id	sid	tid	token	lemma	pos
fnp-2819	1	1	treatment	treatment	NOUN
fnp-2819	1	2	of	of	ADP
fnp-2819	1	3	autoimmune	autoimmune	ADJ
fnp-2819	1	4	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	1	5	with	with	ADP
fnp-2819	1	6	a	a	DET
fnp-2819	1	7	histone	histone	NOUN
fnp-2819	1	8	deacetylase	deacetylase	NOUN
fnp-2819	1	9	inhibitor	inhibitor	NOUN
fnp-2819	1	10	:	:	PUNCT
fnp-2819	1	11	analyzing	analyze	VERB
fnp-2819	1	12	the	the	DET
fnp-2819	1	13	role	role	NOUN
fnp-2819	1	14	of	of	ADP
fnp-2819	1	15	immune	immune	ADJ
fnp-2819	1	16	-	-	PUNCT
fnp-2819	1	17	response	response	NOUN
fnp-2819	1	18	genes	gene	NOUN
fnp-2819	1	19	feel	feel	VERB
fnp-2819	1	20	free	free	ADJ
fnp-2819	1	21	to	to	PART
fnp-2819	1	22	add	add	VERB
fnp-2819	1	23	comments	comment	NOUN
fnp-2819	1	24	by	by	ADP
fnp-2819	1	25	clicking	click	VERB
fnp-2819	1	26	these	these	DET
fnp-2819	1	27	icons	icon	NOUN
fnp-2819	1	28	on	on	ADP
fnp-2819	1	29	the	the	DET
fnp-2819	1	30	sidebar	sidebar	NOUN
fnp-2819	1	31	free	free	ADJ
fnp-2819	1	32	neuropathology	neuropathology	NOUN
fnp-2819	1	33	1:19	1:19	NUM
fnp-2819	1	34	(	(	PUNCT
fnp-2819	1	35	2020	2020	NUM
fnp-2819	1	36	)	)	PUNCT
fnp-2819	1	37	original	original	ADJ
fnp-2819	1	38	paper	paper	NOUN
fnp-2819	1	39	treatment	treatment	NOUN
fnp-2819	1	40	of	of	ADP
fnp-2819	1	41	autoimmune	autoimmune	ADJ
fnp-2819	1	42	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	1	43	with	with	ADP
fnp-2819	1	44	a	a	DET
fnp-2819	1	45	histone	histone	NOUN
fnp-2819	1	46	deacetylase	deacetylase	NOUN
fnp-2819	1	47	inhibitor	inhibitor	NOUN
fnp-2819	1	48	analyzing	analyze	VERB
fnp-2819	1	49	the	the	DET
fnp-2819	1	50	role	role	NOUN
fnp-2819	1	51	of	of	ADP
fnp-2819	1	52	immune	immune	ADJ
fnp-2819	1	53	-	-	PUNCT
fnp-2819	1	54	response	response	NOUN
fnp-2819	1	55	genes	gene	NOUN
fnp-2819	1	56	arathi	arathi	PROPN
fnp-2819	1	57	k.	k.	PROPN
fnp-2819	1	58	jayaraman	jayaraman	PROPN
fnp-2819	1	59	a	a	PROPN
fnp-2819	1	60	,	,	PUNCT
fnp-2819	1	61	karen	karen	PROPN
fnp-2819	1	62	avgush	avgush	PROPN
fnp-2819	1	63	a	a	PROPN
fnp-2819	1	64	,	,	PUNCT
fnp-2819	1	65	rashad	rashad	VERB
fnp-2819	1	66	kulam	kulam	PROPN
fnp-2819	1	67	a	a	PRON
fnp-2819	1	68	,	,	PUNCT
fnp-2819	1	69	advait	advait	PROPN
fnp-2819	1	70	soni	soni	PROPN
fnp-2819	1	71	a	a	X
fnp-2819	1	72	,	,	PUNCT
fnp-2819	1	73	areeb	areeb	PROPN
fnp-2819	1	74	khan	khan	PROPN
fnp-2819	1	75	a	a	PROPN
fnp-2819	1	76	,	,	PUNCT
fnp-2819	1	77	mourad	mourad	PROPN
fnp-2819	1	78	kerdjoudj	kerdjoudj	PROPN
fnp-2819	1	79	a	a	DET
fnp-2819	1	80	,	,	PUNCT
fnp-2819	1	81	sundararajan	sundararajan	NOUN
fnp-2819	1	82	jayaraman	jayaraman	NOUN
fnp-2819	1	83	a	a	PRON
fnp-2819	1	84	,	,	PUNCT
fnp-2819	1	85	b	b	PROPN
fnp-2819	1	86	a	a	DET
fnp-2819	1	87	dept	dept	NOUN
fnp-2819	1	88	.	.	PROPN
fnp-2819	1	89	of	of	ADP
fnp-2819	1	90	microbiology	microbiology	NOUN
fnp-2819	1	91	&	&	CCONJ
fnp-2819	1	92	immunology	immunology	NOUN
fnp-2819	1	93	,	,	PUNCT
fnp-2819	1	94	the	the	DET
fnp-2819	1	95	university	university	PROPN
fnp-2819	1	96	of	of	ADP
fnp-2819	1	97	illinois	illinois	PROPN
fnp-2819	1	98	at	at	ADP
fnp-2819	1	99	chicago	chicago	PROPN
fnp-2819	1	100	,	,	PUNCT
fnp-2819	1	101	909	909	NUM
fnp-2819	1	102	s	s	PROPN
fnp-2819	1	103	wolcott	wolcott	PROPN
fnp-2819	1	104	avenue	avenue	PROPN
fnp-2819	1	105	,	,	PUNCT
fnp-2819	1	106	chicago	chicago	PROPN
fnp-2819	1	107	,	,	PUNCT
fnp-2819	1	108	il	il	PROPN
fnp-2819	1	109	60612	60612	NUM
fnp-2819	1	110	,	,	PUNCT
fnp-2819	1	111	usa	usa	PROPN
fnp-2819	1	112	b	b	PROPN
fnp-2819	1	113	dept	dept	PROPN
fnp-2819	1	114	.	.	PUNCT
fnp-2819	1	115	of	of	ADP
fnp-2819	1	116	surgery	surgery	NOUN
fnp-2819	1	117	,	,	PUNCT
fnp-2819	1	118	the	the	DET
fnp-2819	1	119	university	university	PROPN
fnp-2819	1	120	of	of	ADP
fnp-2819	1	121	illinois	illinois	PROPN
fnp-2819	1	122	college	college	PROPN
fnp-2819	1	123	of	of	ADP
fnp-2819	1	124	medicine	medicine	NOUN
fnp-2819	1	125	at	at	ADP
fnp-2819	1	126	peoria	peoria	PROPN
fnp-2819	1	127	,	,	PUNCT
fnp-2819	1	128	il	il	PROPN
fnp-2819	1	129	61603	61603	NUM
fnp-2819	1	130	,	,	PUNCT
fnp-2819	1	131	usa	usa	PROPN
fnp-2819	1	132	corresponding	corresponding	PROPN
fnp-2819	1	133	author	author	NOUN
fnp-2819	1	134	:	:	PUNCT
fnp-2819	1	135	sundararajan	sundararajan	NOUN
fnp-2819	1	136	jayaraman	jayaraman	PROPN
fnp-2819	1	137	·	·	PUNCT
fnp-2819	1	138	dept	dept	NOUN
fnp-2819	1	139	.	.	PUNCT
fnp-2819	1	140	of	of	ADP
fnp-2819	1	141	surgery	surgery	NOUN
fnp-2819	1	142	·	·	PUNCT
fnp-2819	1	143	the	the	DET
fnp-2819	1	144	university	university	PROPN
fnp-2819	1	145	of	of	ADP
fnp-2819	1	146	illinois	illinois	PROPN
fnp-2819	1	147	college	college	PROPN
fnp-2819	1	148	of	of	ADP
fnp-2819	1	149	medicine	medicine	NOUN
fnp-2819	1	150	at	at	ADP
fnp-2819	1	151	peoria	peoria	PROPN
fnp-2819	1	152	·	·	PUNCT
fnp-2819	2	1	il	il	PROPN
fnp-2819	2	2	61603	61603	NUM
fnp-2819	2	3	·	·	PUNCT
fnp-2819	2	4	usa	usa	PROPN
fnp-2819	2	5	anue2468@uic.edu	anue2468@uic.edu	PROPN
fnp-2819	2	6	submitted	submit	VERB
fnp-2819	2	7	:	:	PUNCT
fnp-2819	2	8	28	28	NUM
fnp-2819	2	9	may	may	PROPN
fnp-2819	2	10	2020	2020	NUM
fnp-2819	2	11	accepted	accept	VERB
fnp-2819	2	12	:	:	PUNCT
fnp-2819	2	13	08	08	NUM
fnp-2819	2	14	july	july	PROPN
fnp-2819	2	15	2020	2020	NUM
fnp-2819	2	16	copyedited	copyedit	VERB
fnp-2819	2	17	by	by	ADP
fnp-2819	2	18	:	:	PUNCT
fnp-2819	2	19	laura	laura	PROPN
fnp-2819	2	20	peferoen	peferoen	PROPN
fnp-2819	2	21	published	publish	VERB
fnp-2819	2	22	:	:	PUNCT
fnp-2819	3	1	14	14	NUM
fnp-2819	3	2	july	july	PROPN
fnp-2819	3	3	2020	2020	NUM
fnp-2819	3	4	https://doi.org/10.17879/freeneuropathology-2020-2819	https://doi.org/10.17879/freeneuropathology-2020-2819	DET
fnp-2819	3	5	additional	additional	ADJ
fnp-2819	3	6	resources	resource	NOUN
fnp-2819	3	7	and	and	CCONJ
fnp-2819	3	8	electronic	electronic	ADJ
fnp-2819	3	9	supplementary	supplementary	ADJ
fnp-2819	3	10	material	material	NOUN
fnp-2819	3	11	:	:	PUNCT
fnp-2819	3	12	supplementary	supplementary	ADJ
fnp-2819	3	13	material	material	NOUN
fnp-2819	3	14	keywords	keyword	NOUN
fnp-2819	3	15	:	:	PUNCT
fnp-2819	3	16	autoreactive	autoreactive	ADJ
fnp-2819	3	17	t	t	PROPN
fnp-2819	3	18	cells	cell	NOUN
fnp-2819	3	19	,	,	PUNCT
fnp-2819	3	20	epigenetic	epigenetic	ADJ
fnp-2819	3	21	regulation	regulation	NOUN
fnp-2819	3	22	,	,	PUNCT
fnp-2819	3	23	gene	gene	NOUN
fnp-2819	3	24	expression	expression	NOUN
fnp-2819	3	25	,	,	PUNCT
fnp-2819	3	26	experimental	experimental	ADJ
fnp-2819	3	27	autoimmune	autoimmune	ADJ
fnp-2819	3	28	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	3	29	,	,	PUNCT
fnp-2819	3	30	trichostatin	trichostatin	NOUN
fnp-2819	3	31	a	a	PRON
fnp-2819	3	32	,	,	PUNCT
fnp-2819	3	33	multiple	multiple	ADJ
fnp-2819	3	34	sclerosis	sclerosis	NOUN
fnp-2819	3	35	abstract	abstract	NOUN
fnp-2819	3	36	we	we	PRON
fnp-2819	3	37	have	have	AUX
fnp-2819	3	38	previously	previously	ADV
fnp-2819	3	39	shown	show	VERB
fnp-2819	3	40	that	that	SCONJ
fnp-2819	3	41	treatment	treatment	NOUN
fnp-2819	3	42	of	of	ADP
fnp-2819	3	43	female	female	ADJ
fnp-2819	3	44	nod	nod	NOUN
fnp-2819	3	45	mice	mouse	NOUN
fnp-2819	3	46	with	with	ADP
fnp-2819	3	47	a	a	DET
fnp-2819	3	48	potent	potent	ADJ
fnp-2819	3	49	nonselective	nonselective	ADJ
fnp-2819	3	50	histone	histone	NOUN
fnp-2819	3	51	deacetylase	deacetylase	NOUN
fnp-2819	3	52	inhibitor	inhibitor	NOUN
fnp-2819	3	53	attenuated	attenuate	VERB
fnp-2819	3	54	experimental	experimental	ADJ
fnp-2819	3	55	autoimmune	autoimmune	ADJ
fnp-2819	3	56	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	3	57	,	,	PUNCT
fnp-2819	3	58	a	a	DET
fnp-2819	3	59	model	model	NOUN
fnp-2819	3	60	for	for	ADP
fnp-2819	3	61	progressive	progressive	ADJ
fnp-2819	3	62	multiple	multiple	ADJ
fnp-2819	3	63	sclerosis	sclerosis	NOUN
fnp-2819	3	64	.	.	PUNCT
fnp-2819	4	1	herein	herein	NOUN
fnp-2819	4	2	we	we	PRON
fnp-2819	4	3	show	show	VERB
fnp-2819	4	4	that	that	SCONJ
fnp-2819	4	5	immunization	immunization	NOUN
fnp-2819	4	6	with	with	ADP
fnp-2819	4	7	the	the	DET
fnp-2819	4	8	mog35	mog35	NOUN
fnp-2819	4	9	-	-	PUNCT
fnp-2819	4	10	55	55	NUM
fnp-2819	4	11	peptide	peptide	NOUN
fnp-2819	4	12	induced	induce	VERB
fnp-2819	4	13	prolonged	prolonged	ADJ
fnp-2819	4	14	upregulation	upregulation	NOUN
fnp-2819	4	15	of	of	ADP
fnp-2819	4	16	genes	gene	NOUN
fnp-2819	4	17	encoding	encode	VERB
fnp-2819	4	18	interleukin	interleukin	NOUN
fnp-2819	4	19	17a	17a	X
fnp-2819	4	20	(	(	PUNCT
fnp-2819	4	21	il-17a	il-17a	PROPN
fnp-2819	4	22	)	)	PUNCT
fnp-2819	4	23	,	,	PUNCT
fnp-2819	4	24	aryl	aryl	NOUN
fnp-2819	4	25	hydrocarbon	hydrocarbon	NOUN
fnp-2819	4	26	receptor	receptor	NOUN
fnp-2819	4	27	,	,	PUNCT
fnp-2819	4	28	and	and	CCONJ
fnp-2819	4	29	histone	histone	NOUN
fnp-2819	4	30	deacetylase	deacetylase	VERB
fnp-2819	4	31	11	11	NUM
fnp-2819	4	32	in	in	ADP
fnp-2819	4	33	the	the	DET
fnp-2819	4	34	spinal	spinal	ADJ
fnp-2819	4	35	cord	cord	NOUN
fnp-2819	4	36	whereas	whereas	SCONJ
fnp-2819	4	37	the	the	DET
fnp-2819	4	38	subunits	subunit	NOUN
fnp-2819	4	39	of	of	ADP
fnp-2819	4	40	il-27	il-27	NUM
fnp-2819	4	41	,	,	PUNCT
fnp-2819	4	42	il-27p28	il-27p28	PROPN
fnp-2819	4	43	and	and	CCONJ
fnp-2819	4	44	il-27ebi3	il-27ebi3	NOUN
fnp-2819	4	45	were	be	AUX
fnp-2819	4	46	significantly	significantly	ADV
fnp-2819	4	47	increased	increase	VERB
fnp-2819	4	48	in	in	ADP
fnp-2819	4	49	secondary	secondary	ADJ
fnp-2819	4	50	lymphoid	lymphoid	NOUN
fnp-2819	4	51	organs	organ	NOUN
fnp-2819	4	52	after	after	ADP
fnp-2819	4	53	a	a	DET
fnp-2819	4	54	lag	lag	NOUN
fnp-2819	4	55	period	period	NOUN
fnp-2819	4	56	.	.	PUNCT
fnp-2819	5	1	interestingly	interestingly	ADV
fnp-2819	5	2	,	,	PUNCT
fnp-2819	5	3	the	the	DET
fnp-2819	5	4	nitric	nitric	ADJ
fnp-2819	5	5	oxide	oxide	NOUN
fnp-2819	5	6	synthase	synthase	NOUN
fnp-2819	5	7	gene	gene	NOUN
fnp-2819	5	8	was	be	AUX
fnp-2819	5	9	prominently	prominently	ADV
fnp-2819	5	10	expressed	express	VERB
fnp-2819	5	11	in	in	ADP
fnp-2819	5	12	both	both	PRON
fnp-2819	5	13	of	of	ADP
fnp-2819	5	14	these	these	DET
fnp-2819	5	15	anatomic	anatomic	ADJ
fnp-2819	5	16	compartments	compartment	NOUN
fnp-2819	5	17	following	follow	VERB
fnp-2819	5	18	immunization	immunization	NOUN
fnp-2819	5	19	.	.	PUNCT
fnp-2819	6	1	treatment	treatment	NOUN
fnp-2819	6	2	with	with	ADP
fnp-2819	6	3	the	the	DET
fnp-2819	6	4	histone	histone	NOUN
fnp-2819	6	5	modifier	modifier	NOUN
fnp-2819	6	6	repressed	repress	VERB
fnp-2819	6	7	the	the	DET
fnp-2819	6	8	transcription	transcription	NOUN
fnp-2819	6	9	of	of	ADP
fnp-2819	6	10	all	all	PRON
fnp-2819	6	11	of	of	ADP
fnp-2819	6	12	these	these	DET
fnp-2819	6	13	genes	gene	NOUN
fnp-2819	6	14	induced	induce	VERB
fnp-2819	6	15	by	by	ADP
fnp-2819	6	16	immunization	immunization	NOUN
fnp-2819	6	17	.	.	PUNCT
fnp-2819	7	1	moreover	moreover	ADV
fnp-2819	7	2	,	,	PUNCT
fnp-2819	7	3	the	the	DET
fnp-2819	7	4	drug	drug	NOUN
fnp-2819	7	5	suppressed	suppress	VERB
fnp-2819	7	6	the	the	DET
fnp-2819	7	7	steady	steady	ADJ
fnp-2819	7	8	-	-	PUNCT
fnp-2819	7	9	state	state	NOUN
fnp-2819	7	10	levels	level	NOUN
fnp-2819	7	11	of	of	ADP
fnp-2819	7	12	the	the	DET
fnp-2819	7	13	migration	migration	NOUN
fnp-2819	7	14	inhibitory	inhibitory	ADJ
fnp-2819	7	15	factor	factor	NOUN
fnp-2819	7	16	and	and	CCONJ
fnp-2819	7	17	cd274	cd274	PROPN
fnp-2819	7	18	genes	gene	NOUN
fnp-2819	7	19	in	in	ADP
fnp-2819	7	20	both	both	CCONJ
fnp-2819	7	21	the	the	DET
fnp-2819	7	22	spinal	spinal	ADJ
fnp-2819	7	23	cord	cord	NOUN
fnp-2819	7	24	and	and	CCONJ
fnp-2819	7	25	peripheral	peripheral	ADJ
fnp-2819	7	26	lymphoid	lymphoid	ADJ
fnp-2819	7	27	tissues	tissue	NOUN
fnp-2819	7	28	.	.	PUNCT
fnp-2819	8	1	at	at	ADP
fnp-2819	8	2	the	the	DET
fnp-2819	8	3	same	same	ADJ
fnp-2819	8	4	time	time	NOUN
fnp-2819	8	5	,	,	PUNCT
fnp-2819	8	6	the	the	DET
fnp-2819	8	7	cd39	cd39	PROPN
fnp-2819	8	8	gene	gene	NOUN
fnp-2819	8	9	was	be	AUX
fnp-2819	8	10	downregulated	downregulate	VERB
fnp-2819	8	11	only	only	ADV
fnp-2819	8	12	in	in	ADP
fnp-2819	8	13	secondary	secondary	ADJ
fnp-2819	8	14	lymphoid	lymphoid	ADJ
fnp-2819	8	15	organs	organ	NOUN
fnp-2819	8	16	.	.	PUNCT
fnp-2819	9	1	paradoxically	paradoxically	ADV
fnp-2819	9	2	,	,	PUNCT
fnp-2819	9	3	the	the	DET
fnp-2819	9	4	epigenetic	epigenetic	ADJ
fnp-2819	9	5	drug	drug	NOUN
fnp-2819	9	6	enhanced	enhance	VERB
fnp-2819	9	7	the	the	DET
fnp-2819	9	8	expression	expression	NOUN
fnp-2819	9	9	of	of	ADP
fnp-2819	9	10	declin-1	declin-1	PROPN
fnp-2819	9	11	in	in	ADP
fnp-2819	9	12	the	the	DET
fnp-2819	9	13	spinal	spinal	NOUN
fnp-2819	9	14	cord	cord	NOUN
fnp-2819	9	15	,	,	PUNCT
fnp-2819	9	16	suggesting	suggest	VERB
fnp-2819	9	17	a	a	DET
fnp-2819	9	18	protective	protective	ADJ
fnp-2819	9	19	role	role	NOUN
fnp-2819	9	20	in	in	ADP
fnp-2819	9	21	neuronal	neuronal	ADJ
fnp-2819	9	22	disease	disease	NOUN
fnp-2819	9	23	.	.	PUNCT
fnp-2819	10	1	immunization	immunization	NOUN
fnp-2819	10	2	profoundly	profoundly	ADV
fnp-2819	10	3	enhanced	enhance	VERB
fnp-2819	10	4	transcription	transcription	NOUN
fnp-2819	10	5	of	of	ADP
fnp-2819	10	6	the	the	DET
fnp-2819	10	7	chemokine	chemokine	ADJ
fnp-2819	10	8	ccl2	ccl2	NOUN
fnp-2819	10	9	in	in	ADP
fnp-2819	10	10	the	the	DET
fnp-2819	10	11	secondary	secondary	ADJ
fnp-2819	10	12	lymphoid	lymphoid	NOUN
fnp-2819	10	13	tissues	tissue	NOUN
fnp-2819	10	14	without	without	ADP
fnp-2819	10	15	a	a	DET
fnp-2819	10	16	corresponding	corresponding	ADJ
fnp-2819	10	17	increase	increase	NOUN
fnp-2819	10	18	in	in	ADP
fnp-2819	10	19	the	the	DET
fnp-2819	10	20	translation	translation	NOUN
fnp-2819	10	21	of	of	ADP
fnp-2819	10	22	ccl2	ccl2	PROPN
fnp-2819	10	23	protein	protein	NOUN
fnp-2819	10	24	.	.	PUNCT
fnp-2819	11	1	histone	histone	NOUN
fnp-2819	11	2	hyperacetylation	hyperacetylation	NOUN
fnp-2819	11	3	neither	neither	CCONJ
fnp-2819	11	4	altered	alter	VERB
fnp-2819	11	5	the	the	DET
fnp-2819	11	6	transcription	transcription	NOUN
fnp-2819	11	7	of	of	ADP
fnp-2819	11	8	ccl2	ccl2	NOUN
fnp-2819	11	9	nor	nor	CCONJ
fnp-2819	11	10	its	its	PRON
fnp-2819	11	11	cognate	cognate	NOUN
fnp-2819	11	12	receptor	receptor	NOUN
fnp-2819	11	13	ccr2	ccr2	NOUN
fnp-2819	11	14	in	in	ADP
fnp-2819	11	15	the	the	DET
fnp-2819	11	16	central	central	ADJ
fnp-2819	11	17	nervous	nervous	ADJ
fnp-2819	11	18	system	system	NOUN
fnp-2819	11	19	and	and	CCONJ
fnp-2819	11	20	peripheral	peripheral	ADJ
fnp-2819	11	21	lymphoid	lymphoid	ADJ
fnp-2819	11	22	tissues	tissue	NOUN
fnp-2819	11	23	.	.	PUNCT
fnp-2819	12	1	surprisingly	surprisingly	ADV
fnp-2819	12	2	,	,	PUNCT
fnp-2819	12	3	the	the	DET
fnp-2819	12	4	drug	drug	NOUN
fnp-2819	12	5	did	do	AUX
fnp-2819	12	6	not	not	PART
fnp-2819	12	7	exert	exert	VERB
fnp-2819	12	8	modulatory	modulatory	ADJ
fnp-2819	12	9	influence	influence	NOUN
fnp-2819	12	10	on	on	ADP
fnp-2819	12	11	most	most	ADJ
fnp-2819	12	12	other	other	ADJ
fnp-2819	12	13	immune	immune	ADJ
fnp-2819	12	14	response	response	NOUN
fnp-2819	12	15	-	-	PUNCT
fnp-2819	12	16	related	relate	VERB
fnp-2819	12	17	genes	gene	NOUN
fnp-2819	12	18	previously	previously	ADV
fnp-2819	12	19	implicated	implicate	VERB
fnp-2819	12	20	in	in	ADP
fnp-2819	12	21	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	12	22	.	.	PUNCT
fnp-2819	13	1	nevertheless	nevertheless	ADV
fnp-2819	13	2	,	,	PUNCT
fnp-2819	13	3	our	our	PRON
fnp-2819	13	4	data	datum	NOUN
fnp-2819	13	5	uncover	uncover	VERB
fnp-2819	13	6	several	several	ADJ
fnp-2819	13	7	potential	potential	ADJ
fnp-2819	13	8	molecular	molecular	ADJ
fnp-2819	13	9	targets	target	NOUN
fnp-2819	13	10	for	for	ADP
fnp-2819	13	11	the	the	DET
fnp-2819	13	12	intervention	intervention	NOUN
fnp-2819	13	13	of	of	ADP
fnp-2819	13	14	experimental	experimental	ADJ
fnp-2819	13	15	autoimmune	autoimmune	ADJ
fnp-2819	13	16	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	13	17	that	that	PRON
fnp-2819	13	18	have	have	VERB
fnp-2819	13	19	implications	implication	NOUN
fnp-2819	13	20	for	for	ADP
fnp-2819	13	21	the	the	DET
fnp-2819	13	22	treatment	treatment	NOUN
fnp-2819	13	23	of	of	ADP
fnp-2819	13	24	progressive	progressive	ADJ
fnp-2819	13	25	multiple	multiple	ADJ
fnp-2819	13	26	sclerosis	sclerosis	NOUN
fnp-2819	13	27	.	.	PUNCT
fnp-2819	14	1	1	1	X
fnp-2819	14	2	.	.	X
fnp-2819	14	3	introduction	introduction	NOUN
fnp-2819	14	4	multiple	multiple	ADJ
fnp-2819	14	5	sclerosis	sclerosis	NOUN
fnp-2819	14	6	(	(	PUNCT
fnp-2819	14	7	ms	ms	NOUN
fnp-2819	14	8	)	)	PUNCT
fnp-2819	14	9	,	,	PUNCT
fnp-2819	14	10	an	an	DET
fnp-2819	14	11	inflammatory	inflammatory	ADJ
fnp-2819	14	12	disease	disease	NOUN
fnp-2819	14	13	of	of	ADP
fnp-2819	14	14	the	the	DET
fnp-2819	14	15	central	central	ADJ
fnp-2819	14	16	nervous	nervous	ADJ
fnp-2819	14	17	system	system	NOUN
fnp-2819	14	18	(	(	PUNCT
fnp-2819	14	19	cns	cns	NOUN
fnp-2819	14	20	)	)	PUNCT
fnp-2819	14	21	,	,	PUNCT
fnp-2819	14	22	manifests	manifest	VERB
fnp-2819	14	23	commonly	commonly	ADV
fnp-2819	14	24	as	as	ADP
fnp-2819	14	25	the	the	DET
fnp-2819	14	26	relapsing	relapse	VERB
fnp-2819	14	27	-	-	PUNCT
fnp-2819	14	28	remitting	remit	VERB
fnp-2819	14	29	disease	disease	NOUN
fnp-2819	14	30	.	.	PUNCT
fnp-2819	15	1	some	some	DET
fnp-2819	15	2	patients	patient	NOUN
fnp-2819	15	3	develop	develop	VERB
fnp-2819	15	4	primary	primary	ADJ
fnp-2819	15	5	and	and	CCONJ
fnp-2819	15	6	secondary	secondary	ADJ
fnp-2819	15	7	progressive	progressive	ADJ
fnp-2819	15	8	forms	form	NOUN
fnp-2819	15	9	of	of	ADP
fnp-2819	15	10	disease	disease	NOUN
fnp-2819	15	11	(	(	PUNCT
fnp-2819	15	12	dendrou	dendrou	PROPN
fnp-2819	15	13	et	et	PROPN
fnp-2819	15	14	al	al	PROPN
fnp-2819	15	15	.	.	PROPN
fnp-2819	15	16	,	,	PUNCT
fnp-2819	15	17	2015	2015	NUM
fnp-2819	15	18	;	;	PUNCT
fnp-2819	15	19	lassmann	lassmann	PROPN
fnp-2819	15	20	,	,	PUNCT
fnp-2819	15	21	2017	2017	NUM
fnp-2819	15	22	)	)	PUNCT
fnp-2819	15	23	.	.	PUNCT
fnp-2819	16	1	the	the	DET
fnp-2819	16	2	term	term	NOUN
fnp-2819	16	3	‘	'	PUNCT
fnp-2819	16	4	progressive	progressive	ADJ
fnp-2819	16	5	multiple	multiple	ADJ
fnp-2819	16	6	sclerosis	sclerosis	NOUN
fnp-2819	16	7	’	'	PUNCT
fnp-2819	16	8	has	have	AUX
fnp-2819	16	9	been	be	AUX
fnp-2819	16	10	proposed	propose	VERB
fnp-2819	16	11	to	to	PART
fnp-2819	16	12	encompass	encompass	VERB
fnp-2819	16	13	the	the	DET
fnp-2819	16	14	primary	primary	ADJ
fnp-2819	16	15	and	and	CCONJ
fnp-2819	16	16	secondary	secondary	ADJ
fnp-2819	16	17	progressive	progressive	ADJ
fnp-2819	16	18	multiple	multiple	ADJ
fnp-2819	16	19	sclerosis	sclerosis	NOUN
fnp-2819	16	20	since	since	SCONJ
fnp-2819	16	21	there	there	PRON
fnp-2819	16	22	are	be	VERB
fnp-2819	16	23	more	more	ADJ
fnp-2819	16	24	similarities	similarity	NOUN
fnp-2819	16	25	than	than	ADP
fnp-2819	16	26	differences	difference	NOUN
fnp-2819	16	27	between	between	ADP
fnp-2819	16	28	them	they	PRON
fnp-2819	16	29	(	(	PUNCT
fnp-2819	16	30	fox	fox	NOUN
fnp-2819	16	31	and	and	CCONJ
fnp-2819	16	32	chataway	chataway	PROPN
fnp-2819	16	33	,	,	PUNCT
fnp-2819	16	34	2017	2017	NUM
fnp-2819	16	35	)	)	PUNCT
fnp-2819	16	36	.	.	PUNCT
fnp-2819	17	1	although	although	SCONJ
fnp-2819	17	2	many	many	ADJ
fnp-2819	17	3	drugs	drug	NOUN
fnp-2819	17	4	are	be	AUX
fnp-2819	17	5	effective	effective	ADJ
fnp-2819	17	6	in	in	ADP
fnp-2819	17	7	reducing	reduce	VERB
fnp-2819	17	8	relapses	relapse	NOUN
fnp-2819	17	9	,	,	PUNCT
fnp-2819	17	10	they	they	PRON
fnp-2819	17	11	failed	fail	VERB
fnp-2819	17	12	to	to	PART
fnp-2819	17	13	reverse	reverse	VERB
fnp-2819	17	14	axonal	axonal	ADJ
fnp-2819	17	15	degeneration	degeneration	NOUN
fnp-2819	17	16	and	and	CCONJ
fnp-2819	17	17	are	be	AUX
fnp-2819	17	18	sometimes	sometimes	ADV
fnp-2819	17	19	associated	associate	VERB
fnp-2819	17	20	with	with	ADP
fnp-2819	17	21	adverse	adverse	ADJ
fnp-2819	17	22	side	side	NOUN
fnp-2819	17	23	effects	effect	NOUN
fnp-2819	17	24	,	,	PUNCT
fnp-2819	17	25	including	include	VERB
fnp-2819	17	26	progressive	progressive	ADJ
fnp-2819	17	27	multifocal	multifocal	ADJ
fnp-2819	17	28	leukoencephalopathy	leukoencephalopathy	NOUN
fnp-2819	17	29	(	(	PUNCT
fnp-2819	17	30	wingerchuk	wingerchuk	NOUN
fnp-2819	17	31	and	and	CCONJ
fnp-2819	17	32	carter	carter	PROPN
fnp-2819	17	33	,	,	PUNCT
fnp-2819	17	34	2014	2014	NUM
fnp-2819	17	35	;	;	PUNCT
fnp-2819	17	36	tintore	tintore	PROPN
fnp-2819	17	37	et	et	PROPN
fnp-2819	17	38	al	al	PROPN
fnp-2819	17	39	.	.	PROPN
fnp-2819	17	40	,	,	PUNCT
fnp-2819	17	41	2019	2019	NUM
fnp-2819	17	42	)	)	PUNCT
fnp-2819	17	43	.	.	PUNCT
fnp-2819	18	1	thus	thus	ADV
fnp-2819	18	2	,	,	PUNCT
fnp-2819	18	3	effective	effective	ADJ
fnp-2819	18	4	drugs	drug	NOUN
fnp-2819	18	5	for	for	ADP
fnp-2819	18	6	the	the	DET
fnp-2819	18	7	treatment	treatment	NOUN
fnp-2819	18	8	of	of	ADP
fnp-2819	18	9	progressive	progressive	ADJ
fnp-2819	18	10	multiple	multiple	ADJ
fnp-2819	18	11	sclerosis	sclerosis	NOUN
fnp-2819	18	12	remain	remain	VERB
fnp-2819	18	13	an	an	DET
fnp-2819	18	14	unmet	unmet	NOUN
fnp-2819	18	15	need	need	NOUN
fnp-2819	18	16	.	.	PUNCT
fnp-2819	19	1	since	since	SCONJ
fnp-2819	19	2	the	the	DET
fnp-2819	19	3	early	early	ADJ
fnp-2819	19	4	description	description	NOUN
fnp-2819	19	5	of	of	ADP
fnp-2819	19	6	the	the	DET
fnp-2819	19	7	experimental	experimental	ADJ
fnp-2819	19	8	autoimmune	autoimmune	ADJ
fnp-2819	19	9	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	19	10	(	(	PUNCT
fnp-2819	19	11	eae	eae	PROPN
fnp-2819	19	12	)	)	PUNCT
fnp-2819	19	13	in	in	ADP
fnp-2819	19	14	monkeys	monkey	NOUN
fnp-2819	19	15	(	(	PUNCT
fnp-2819	19	16	rivers	river	NOUN
fnp-2819	19	17	et	et	PROPN
fnp-2819	19	18	al	al	PROPN
fnp-2819	19	19	.	.	PROPN
fnp-2819	19	20	,	,	PUNCT
fnp-2819	19	21	1933	1933	NUM
fnp-2819	19	22	)	)	PUNCT
fnp-2819	19	23	,	,	PUNCT
fnp-2819	19	24	monophasic	monophasic	NOUN
fnp-2819	19	25	,	,	PUNCT
fnp-2819	19	26	self	self	NOUN
fnp-2819	19	27	-	-	PUNCT
fnp-2819	19	28	resolving	resolving	NOUN
fnp-2819	19	29	,	,	PUNCT
fnp-2819	19	30	‘	'	PUNCT
fnp-2819	19	31	classic	classic	ADJ
fnp-2819	19	32	’	'	PUNCT
fnp-2819	19	33	eae	eae	PROPN
fnp-2819	19	34	,	,	PUNCT
fnp-2819	19	35	as	as	ADV
fnp-2819	19	36	well	well	ADV
fnp-2819	19	37	as	as	ADP
fnp-2819	19	38	‘	'	PUNCT
fnp-2819	19	39	atypical	atypical	ADJ
fnp-2819	19	40	’	'	PUNCT
fnp-2819	19	41	eae	eae	PROPN
fnp-2819	19	42	,	,	PUNCT
fnp-2819	19	43	have	have	AUX
fnp-2819	19	44	been	be	AUX
fnp-2819	19	45	induced	induce	VERB
fnp-2819	19	46	in	in	ADP
fnp-2819	19	47	rats	rat	NOUN
fnp-2819	19	48	and	and	CCONJ
fnp-2819	19	49	mice	mouse	NOUN
fnp-2819	19	50	using	use	VERB
fnp-2819	19	51	whole	whole	ADJ
fnp-2819	19	52	spinal	spinal	ADJ
fnp-2819	19	53	cord	cord	NOUN
fnp-2819	19	54	homogenates	homogenate	NOUN
fnp-2819	19	55	or	or	CCONJ
fnp-2819	19	56	peptides	peptide	NOUN
fnp-2819	19	57	derived	derive	VERB
fnp-2819	19	58	from	from	ADP
fnp-2819	19	59	the	the	DET
fnp-2819	19	60	cns	cns	PROPN
fnp-2819	19	61	components	component	NOUN
fnp-2819	19	62	such	such	ADJ
fnp-2819	19	63	as	as	ADP
fnp-2819	19	64	myelin	myelin	ADJ
fnp-2819	19	65	oligodendrocyte	oligodendrocyte	ADJ
fnp-2819	19	66	glycoprotein	glycoprotein	NOUN
fnp-2819	19	67	(	(	PUNCT
fnp-2819	19	68	mog	mog	NOUN
fnp-2819	19	69	)	)	PUNCT
fnp-2819	19	70	,	,	PUNCT
fnp-2819	19	71	myelin	myelin	NOUN
fnp-2819	19	72	basic	basic	ADJ
fnp-2819	19	73	protein	protein	NOUN
fnp-2819	19	74	(	(	PUNCT
fnp-2819	19	75	mbp	mbp	NOUN
fnp-2819	19	76	)	)	PUNCT
fnp-2819	19	77	and	and	CCONJ
fnp-2819	19	78	proteolipid	proteolipid	NOUN
fnp-2819	19	79	protein	protein	NOUN
fnp-2819	19	80	(	(	PUNCT
fnp-2819	19	81	plp)(dendrou	plp)(dendrou	PROPN
fnp-2819	19	82	et	et	PROPN
fnp-2819	19	83	al	al	PROPN
fnp-2819	19	84	.	.	PROPN
fnp-2819	19	85	,	,	PUNCT
fnp-2819	19	86	2015	2015	NUM
fnp-2819	19	87	;	;	PUNCT
fnp-2819	19	88	lassmann	lassmann	NOUN
fnp-2819	19	89	and	and	CCONJ
fnp-2819	19	90	bradl	bradl	NOUN
fnp-2819	19	91	,	,	PUNCT
fnp-2819	19	92	2017	2017	NUM
fnp-2819	19	93	)	)	PUNCT
fnp-2819	19	94	.	.	PUNCT
fnp-2819	20	1	autoimmune	autoimmune	ADJ
fnp-2819	20	2	-	-	PUNCT
fnp-2819	20	3	prone	prone	ADJ
fnp-2819	20	4	female	female	ADJ
fnp-2819	20	5	non	non	ADJ
fnp-2819	20	6	-	-	ADJ
fnp-2819	20	7	obese	obese	ADJ
fnp-2819	20	8	diabetic	diabetic	ADJ
fnp-2819	20	9	(	(	PUNCT
fnp-2819	20	10	nod	nod	NOUN
fnp-2819	20	11	)	)	PUNCT
fnp-2819	20	12	mice	mouse	NOUN
fnp-2819	20	13	immunized	immunize	VERB
fnp-2819	20	14	with	with	ADP
fnp-2819	20	15	the	the	DET
fnp-2819	20	16	mog35	mog35	NOUN
fnp-2819	20	17	-	-	PUNCT
fnp-2819	20	18	55	55	NUM
fnp-2819	20	19	peptide	peptide	NOUN
fnp-2819	20	20	consistently	consistently	ADV
fnp-2819	20	21	induced	induce	VERB
fnp-2819	20	22	severe	severe	ADJ
fnp-2819	20	23	and	and	CCONJ
fnp-2819	20	24	long	long	ADV
fnp-2819	20	25	-	-	PUNCT
fnp-2819	20	26	lasting	last	VERB
fnp-2819	20	27	progressive	progressive	ADJ
fnp-2819	20	28	eae	eae	NOUN
fnp-2819	20	29	(	(	PUNCT
fnp-2819	20	30	peae	peae	PROPN
fnp-2819	20	31	)	)	PUNCT
fnp-2819	20	32	in	in	ADP
fnp-2819	20	33	100	100	NUM
fnp-2819	20	34	%	%	NOUN
fnp-2819	20	35	of	of	ADP
fnp-2819	20	36	animals	animal	NOUN
fnp-2819	20	37	characterized	characterize	VERB
fnp-2819	20	38	by	by	ADP
fnp-2819	20	39	paralysis	paralysis	NOUN
fnp-2819	20	40	of	of	ADP
fnp-2819	20	41	fore	fore	NOUN
fnp-2819	20	42	and	and	CCONJ
fnp-2819	20	43	hind	hind	NOUN
fnp-2819	20	44	limbs	limb	NOUN
fnp-2819	20	45	with	with	ADP
fnp-2819	20	46	(	(	PUNCT
fnp-2819	20	47	slavin	slavin	NOUN
fnp-2819	20	48	et	et	PROPN
fnp-2819	20	49	al	al	PROPN
fnp-2819	20	50	.	.	PROPN
fnp-2819	20	51	,	,	PUNCT
fnp-2819	20	52	1998	1998	NUM
fnp-2819	20	53	;	;	PUNCT
fnp-2819	20	54	hidaka	hidaka	PROPN
fnp-2819	20	55	et	et	PROPN
fnp-2819	20	56	al	al	PROPN
fnp-2819	20	57	.	.	PROPN
fnp-2819	20	58	,	,	PUNCT
fnp-2819	20	59	2014	2014	NUM
fnp-2819	20	60	;	;	PUNCT
fnp-2819	20	61	dang	dang	INTJ
fnp-2819	20	62	et	et	PROPN
fnp-2819	20	63	al	al	PROPN
fnp-2819	20	64	.	.	PROPN
fnp-2819	20	65	,	,	PUNCT
fnp-2819	20	66	2015	2015	NUM
fnp-2819	20	67	)	)	PUNCT
fnp-2819	20	68	or	or	CCONJ
fnp-2819	20	69	without	without	ADP
fnp-2819	20	70	discernible	discernible	ADJ
fnp-2819	20	71	remissions	remission	NOUN
fnp-2819	20	72	(	(	PUNCT
fnp-2819	20	73	basso	basso	NOUN
fnp-2819	20	74	et	et	PROPN
fnp-2819	20	75	al	al	PROPN
fnp-2819	20	76	.	.	PROPN
fnp-2819	20	77	,	,	PUNCT
fnp-2819	20	78	2008	2008	NUM
fnp-2819	20	79	;	;	PUNCT
fnp-2819	20	80	jayaraman	jayaraman	NOUN
fnp-2819	20	81	et	et	PROPN
fnp-2819	20	82	al	al	PROPN
fnp-2819	20	83	.	.	PROPN
fnp-2819	20	84	,	,	PUNCT
fnp-2819	20	85	2017	2017	NUM
fnp-2819	20	86	;	;	PUNCT
fnp-2819	20	87	2018	2018	NUM
fnp-2819	20	88	)	)	PUNCT
fnp-2819	20	89	.	.	PUNCT
fnp-2819	21	1	regardless	regardless	ADV
fnp-2819	21	2	,	,	PUNCT
fnp-2819	21	3	peae	peae	PROPN
fnp-2819	21	4	induced	induce	VERB
fnp-2819	21	5	in	in	ADP
fnp-2819	21	6	nod	nod	NOUN
fnp-2819	21	7	mice	mouse	NOUN
fnp-2819	21	8	mimics	mimic	VERB
fnp-2819	21	9	features	feature	NOUN
fnp-2819	21	10	of	of	ADP
fnp-2819	21	11	progressive	progressive	ADJ
fnp-2819	21	12	ms	ms	NOUN
fnp-2819	21	13	including	include	VERB
fnp-2819	21	14	the	the	DET
fnp-2819	21	15	life	life	NOUN
fnp-2819	21	16	-	-	PUNCT
fnp-2819	21	17	long	long	ADJ
fnp-2819	21	18	disease	disease	NOUN
fnp-2819	21	19	,	,	PUNCT
fnp-2819	21	20	prominent	prominent	ADJ
fnp-2819	21	21	demyelination	demyelination	NOUN
fnp-2819	21	22	,	,	PUNCT
fnp-2819	21	23	axonal	axonal	ADJ
fnp-2819	21	24	loss	loss	NOUN
fnp-2819	21	25	,	,	PUNCT
fnp-2819	21	26	and	and	CCONJ
fnp-2819	21	27	astrogliosis	astrogliosis	NOUN
fnp-2819	21	28	(	(	PUNCT
fnp-2819	21	29	slavin	slavin	NOUN
fnp-2819	21	30	et	et	PROPN
fnp-2819	21	31	al	al	PROPN
fnp-2819	21	32	.	.	PROPN
fnp-2819	21	33	,	,	PUNCT
fnp-2819	21	34	1998	1998	NUM
fnp-2819	21	35	;	;	PUNCT
fnp-2819	21	36	basso	basso	PROPN
fnp-2819	21	37	et	et	PROPN
fnp-2819	21	38	al	al	PROPN
fnp-2819	21	39	.	.	PROPN
fnp-2819	21	40	,	,	PUNCT
fnp-2819	21	41	2008	2008	NUM
fnp-2819	21	42	;	;	PUNCT
fnp-2819	21	43	hidaka	hidaka	PROPN
fnp-2819	21	44	et	et	PROPN
fnp-2819	21	45	al	al	PROPN
fnp-2819	21	46	.	.	PROPN
fnp-2819	21	47	,	,	PUNCT
fnp-2819	21	48	2014	2014	NUM
fnp-2819	21	49	;	;	PUNCT
fnp-2819	21	50	dang	dang	INTJ
fnp-2819	21	51	et	et	PROPN
fnp-2819	21	52	al	al	PROPN
fnp-2819	21	53	.	.	PROPN
fnp-2819	21	54	,	,	PUNCT
fnp-2819	21	55	2015	2015	NUM
fnp-2819	21	56	;	;	PUNCT
fnp-2819	21	57	jayaraman	jayaraman	NOUN
fnp-2819	21	58	et	et	PROPN
fnp-2819	21	59	al	al	PROPN
fnp-2819	21	60	.	.	PROPN
fnp-2819	21	61	,	,	PUNCT
fnp-2819	21	62	2017	2017	NUM
fnp-2819	21	63	;	;	PUNCT
fnp-2819	21	64	2018	2018	NUM
fnp-2819	21	65	)	)	PUNCT
fnp-2819	21	66	,	,	PUNCT
fnp-2819	21	67	and	and	CCONJ
fnp-2819	21	68	hence	hence	ADV
fnp-2819	21	69	is	be	AUX
fnp-2819	21	70	ideal	ideal	ADJ
fnp-2819	21	71	for	for	ADP
fnp-2819	21	72	testing	test	VERB
fnp-2819	21	73	the	the	DET
fnp-2819	21	74	efficacy	efficacy	NOUN
fnp-2819	21	75	of	of	ADP
fnp-2819	21	76	new	new	ADJ
fnp-2819	21	77	drugs	drug	NOUN
fnp-2819	21	78	to	to	PART
fnp-2819	21	79	treat	treat	VERB
fnp-2819	21	80	progressive	progressive	ADJ
fnp-2819	21	81	ms	ms	PROPN
fnp-2819	21	82	.	.	PROPN
fnp-2819	22	1	the	the	DET
fnp-2819	22	2	eae	eae	PROPN
fnp-2819	22	3	model	model	NOUN
fnp-2819	22	4	is	be	AUX
fnp-2819	22	5	amenable	amenable	ADJ
fnp-2819	22	6	for	for	ADP
fnp-2819	22	7	the	the	DET
fnp-2819	22	8	investigation	investigation	NOUN
fnp-2819	22	9	of	of	ADP
fnp-2819	22	10	the	the	DET
fnp-2819	22	11	genes	gene	NOUN
fnp-2819	22	12	critically	critically	ADV
fnp-2819	22	13	involved	involve	VERB
fnp-2819	22	14	in	in	ADP
fnp-2819	22	15	ms	ms	ADJ
fnp-2819	22	16	pathogenesis	pathogenesis	NOUN
fnp-2819	22	17	.	.	PUNCT
fnp-2819	23	1	previous	previous	ADJ
fnp-2819	23	2	studies	study	NOUN
fnp-2819	23	3	analyzed	analyze	VERB
fnp-2819	23	4	the	the	DET
fnp-2819	23	5	roles	role	NOUN
fnp-2819	23	6	of	of	ADP
fnp-2819	23	7	various	various	ADJ
fnp-2819	23	8	immune	immune	ADJ
fnp-2819	23	9	response	response	NOUN
fnp-2819	23	10	-	-	PUNCT
fnp-2819	23	11	related	relate	VERB
fnp-2819	23	12	genes	gene	NOUN
fnp-2819	23	13	in	in	ADP
fnp-2819	23	14	eae	eae	PROPN
fnp-2819	23	15	using	use	VERB
fnp-2819	23	16	gene	gene	NOUN
fnp-2819	23	17	knockout	knockout	NOUN
fnp-2819	23	18	mice	mouse	NOUN
fnp-2819	23	19	and	and	CCONJ
fnp-2819	23	20	specific	specific	ADJ
fnp-2819	23	21	neutralizing	neutralizing	ADJ
fnp-2819	23	22	antibodies	antibody	NOUN
fnp-2819	23	23	in	in	ADP
fnp-2819	23	24	wild	wild	ADJ
fnp-2819	23	25	-	-	PUNCT
fnp-2819	23	26	type	type	NOUN
fnp-2819	23	27	mice	mouse	NOUN
fnp-2819	23	28	.	.	PUNCT
fnp-2819	24	1	these	these	DET
fnp-2819	24	2	studies	study	NOUN
fnp-2819	24	3	investigated	investigate	VERB
fnp-2819	24	4	the	the	DET
fnp-2819	24	5	role	role	NOUN
fnp-2819	24	6	of	of	ADP
fnp-2819	24	7	t	t	PROPN
fnp-2819	24	8	helper	helper	NOUN
fnp-2819	24	9	1	1	NUM
fnp-2819	24	10	(	(	PUNCT
fnp-2819	24	11	th1	th1	NOUN
fnp-2819	24	12	)	)	PUNCT
fnp-2819	24	13	,	,	PUNCT
fnp-2819	24	14	th17	th17	PROPN
fnp-2819	24	15	,	,	PUNCT
fnp-2819	24	16	and	and	CCONJ
fnp-2819	24	17	th1	th1	PROPN
fnp-2819	24	18	/	/	SYM
fnp-2819	24	19	th17	th17	PROPN
fnp-2819	24	20	(	(	PUNCT
fnp-2819	24	21	th17.1	th17.1	NUM
fnp-2819	24	22	)	)	PUNCT
fnp-2819	24	23	subsets	subset	NOUN
fnp-2819	24	24	as	as	ADV
fnp-2819	24	25	well	well	ADV
fnp-2819	24	26	as	as	ADP
fnp-2819	24	27	lymphokines	lymphokine	NOUN
fnp-2819	24	28	such	such	ADJ
fnp-2819	24	29	as	as	ADP
fnp-2819	24	30	interferon	interferon	ADJ
fnp-2819	24	31	-	-	PUNCT
fnp-2819	24	32	γ	γ	NOUN
fnp-2819	24	33	(	(	PUNCT
fnp-2819	24	34	ifnγ	ifnγ	NOUN
fnp-2819	24	35	)	)	PUNCT
fnp-2819	24	36	(	(	PUNCT
fnp-2819	24	37	ferber	ferber	PROPN
fnp-2819	24	38	et	et	PROPN
fnp-2819	24	39	al	al	PROPN
fnp-2819	24	40	.	.	PROPN
fnp-2819	24	41	,	,	PUNCT
fnp-2819	24	42	1996	1996	NUM
fnp-2819	24	43	;	;	PUNCT
fnp-2819	24	44	okuda	okuda	NOUN
fnp-2819	24	45	et	et	PROPN
fnp-2819	24	46	al	al	PROPN
fnp-2819	24	47	.	.	PROPN
fnp-2819	24	48	,	,	PUNCT
fnp-2819	24	49	1998	1998	NUM
fnp-2819	24	50	;	;	PUNCT
fnp-2819	24	51	hidaka	hidaka	PROPN
fnp-2819	24	52	et	et	PROPN
fnp-2819	24	53	al	al	PROPN
fnp-2819	24	54	.	.	PROPN
fnp-2819	24	55	,	,	PUNCT
fnp-2819	24	56	2014	2014	NUM
fnp-2819	24	57	)	)	PUNCT
fnp-2819	24	58	,	,	PUNCT
fnp-2819	24	59	interleukin-4	interleukin-4	PROPN
fnp-2819	24	60	(	(	PUNCT
fnp-2819	24	61	il-4	il-4	NUM
fnp-2819	24	62	)	)	PUNCT
fnp-2819	24	63	(	(	PUNCT
fnp-2819	24	64	falcone	falcone	PROPN
fnp-2819	24	65	et	et	PROPN
fnp-2819	24	66	al	al	PROPN
fnp-2819	24	67	.	.	PROPN
fnp-2819	24	68	,	,	PUNCT
fnp-2819	24	69	1998	1998	NUM
fnp-2819	24	70	;	;	PUNCT
fnp-2819	24	71	okuda	okuda	NOUN
fnp-2819	24	72	et	et	PROPN
fnp-2819	24	73	al	al	PROPN
fnp-2819	24	74	.	.	PROPN
fnp-2819	24	75	,	,	PUNCT
fnp-2819	24	76	1998	1998	NUM
fnp-2819	24	77	;	;	PUNCT
fnp-2819	24	78	ponomarev	ponomarev	PROPN
fnp-2819	24	79	et	et	PROPN
fnp-2819	24	80	al	al	PROPN
fnp-2819	24	81	.	.	PROPN
fnp-2819	24	82	,	,	PUNCT
fnp-2819	24	83	2007	2007	NUM
fnp-2819	24	84	)	)	PUNCT
fnp-2819	24	85	,	,	PUNCT
fnp-2819	24	86	il-17a	il-17a	PROPN
fnp-2819	24	87	(	(	PUNCT
fnp-2819	24	88	evangelidou	evangelidou	NOUN
fnp-2819	24	89	et	et	PROPN
fnp-2819	24	90	al	al	PROPN
fnp-2819	24	91	.	.	PROPN
fnp-2819	24	92	,	,	PUNCT
fnp-2819	24	93	2014	2014	NUM
fnp-2819	24	94	)	)	PUNCT
fnp-2819	24	95	,	,	PUNCT
fnp-2819	24	96	il-10	il-10	PRON
fnp-2819	24	97	,	,	PUNCT
fnp-2819	24	98	colony	colony	NOUN
fnp-2819	24	99	-	-	PUNCT
fnp-2819	24	100	stimulating	stimulate	VERB
fnp-2819	24	101	factor	factor	NOUN
fnp-2819	24	102	1	1	NUM
fnp-2819	24	103	(	(	PUNCT
fnp-2819	24	104	borjini	borjini	NOUN
fnp-2819	24	105	et	et	PROPN
fnp-2819	24	106	al	al	PROPN
fnp-2819	24	107	.	.	PROPN
fnp-2819	24	108	,	,	PUNCT
fnp-2819	24	109	2016	2016	NUM
fnp-2819	24	110	)	)	PUNCT
fnp-2819	24	111	,	,	PUNCT
fnp-2819	24	112	il-22	il-22	PUNCT
fnp-2819	24	113	(	(	PUNCT
fnp-2819	24	114	kreymborg	kreymborg	PROPN
fnp-2819	24	115	et	et	PROPN
fnp-2819	24	116	al	al	PROPN
fnp-2819	24	117	.	.	PROPN
fnp-2819	24	118	,	,	PUNCT
fnp-2819	24	119	2007	2007	NUM
fnp-2819	24	120	)	)	PUNCT
fnp-2819	24	121	,	,	PUNCT
fnp-2819	24	122	transforming	transform	VERB
fnp-2819	24	123	growth	growth	NOUN
fnp-2819	24	124	factor	factor	NOUN
fnp-2819	24	125	-	-	PUNCT
fnp-2819	24	126	β	β	X
fnp-2819	24	127	(	(	PUNCT
fnp-2819	24	128	tgf	tgf	PROPN
fnp-2819	24	129	-	-	PUNCT
fnp-2819	24	130	β	β	PROPN
fnp-2819	24	131	(	(	PUNCT
fnp-2819	24	132	okuda	okuda	NOUN
fnp-2819	24	133	et	et	PROPN
fnp-2819	24	134	al	al	PROPN
fnp-2819	24	135	.	.	PROPN
fnp-2819	24	136	,	,	PUNCT
fnp-2819	24	137	1998	1998	NUM
fnp-2819	24	138	)	)	PUNCT
fnp-2819	24	139	and	and	CCONJ
fnp-2819	24	140	il-27	il-27	PROPN
fnp-2819	24	141	(	(	PUNCT
fnp-2819	24	142	li	li	PROPN
fnp-2819	24	143	et	et	PROPN
fnp-2819	24	144	al	al	PROPN
fnp-2819	24	145	.	.	PROPN
fnp-2819	24	146	,	,	PUNCT
fnp-2819	24	147	2005	2005	NUM
fnp-2819	24	148	)	)	PUNCT
fnp-2819	24	149	in	in	ADP
fnp-2819	24	150	eae	eae	PROPN
fnp-2819	24	151	.	.	PUNCT
fnp-2819	25	1	similarly	similarly	ADV
fnp-2819	25	2	,	,	PUNCT
fnp-2819	25	3	the	the	DET
fnp-2819	25	4	importance	importance	NOUN
fnp-2819	25	5	of	of	ADP
fnp-2819	25	6	the	the	DET
fnp-2819	25	7	transcription	transcription	NOUN
fnp-2819	25	8	factors	factor	VERB
fnp-2819	25	9	t	t	NOUN
fnp-2819	25	10	-	-	PUNCT
fnp-2819	25	11	bet	bet	NOUN
fnp-2819	25	12	(	(	PUNCT
fnp-2819	25	13	o’connor	o’connor	ADV
fnp-2819	25	14	et	et	PROPN
fnp-2819	25	15	al	al	PROPN
fnp-2819	25	16	.	.	PROPN
fnp-2819	25	17	,	,	PUNCT
fnp-2819	25	18	2013	2013	NUM
fnp-2819	25	19	)	)	PUNCT
fnp-2819	25	20	,	,	PUNCT
fnp-2819	25	21	gata-3	gata-3	PROPN
fnp-2819	25	22	(	(	PUNCT
fnp-2819	25	23	fernando	fernando	PROPN
fnp-2819	25	24	et	et	PROPN
fnp-2819	25	25	al	al	PROPN
fnp-2819	25	26	.	.	PROPN
fnp-2819	25	27	,	,	PUNCT
fnp-2819	25	28	2014	2014	NUM
fnp-2819	25	29	)	)	PUNCT
fnp-2819	25	30	,	,	PUNCT
fnp-2819	25	31	and	and	CCONJ
fnp-2819	25	32	rorγt	rorγt	NOUN
fnp-2819	25	33	(	(	PUNCT
fnp-2819	25	34	martinez	martinez	PROPN
fnp-2819	25	35	et	et	PROPN
fnp-2819	25	36	al	al	PROPN
fnp-2819	25	37	.	.	PROPN
fnp-2819	25	38	,	,	PUNCT
fnp-2819	25	39	2014	2014	NUM
fnp-2819	25	40	)	)	PUNCT
fnp-2819	25	41	respectively	respectively	ADV
fnp-2819	25	42	,	,	PUNCT
fnp-2819	25	43	involved	involve	VERB
fnp-2819	25	44	in	in	ADP
fnp-2819	25	45	the	the	DET
fnp-2819	25	46	transcription	transcription	NOUN
fnp-2819	25	47	of	of	ADP
fnp-2819	25	48	ifn	ifn	PROPN
fnp-2819	25	49	-	-	PUNCT
fnp-2819	25	50	γ	γ	NOUN
fnp-2819	25	51	,	,	PUNCT
fnp-2819	25	52	il-4	il-4	PRON
fnp-2819	25	53	,	,	PUNCT
fnp-2819	25	54	and	and	CCONJ
fnp-2819	25	55	il-17a	il-17a	PROPN
fnp-2819	25	56	,	,	PUNCT
fnp-2819	25	57	was	be	AUX
fnp-2819	25	58	also	also	ADV
fnp-2819	25	59	studied	study	VERB
fnp-2819	25	60	in	in	ADP
fnp-2819	25	61	eae	eae	PROPN
fnp-2819	25	62	models	model	NOUN
fnp-2819	25	63	.	.	PUNCT
fnp-2819	26	1	moreover	moreover	ADV
fnp-2819	26	2	,	,	PUNCT
fnp-2819	26	3	the	the	DET
fnp-2819	26	4	factors	factor	NOUN
fnp-2819	26	5	required	require	VERB
fnp-2819	26	6	for	for	ADP
fnp-2819	26	7	the	the	DET
fnp-2819	26	8	induction	induction	NOUN
fnp-2819	26	9	of	of	ADP
fnp-2819	26	10	th1	th1	PROPN
fnp-2819	26	11	cells	cell	NOUN
fnp-2819	26	12	such	such	ADJ
fnp-2819	26	13	as	as	ADP
fnp-2819	26	14	il-12	il-12	NOUN
fnp-2819	26	15	(	(	PUNCT
fnp-2819	26	16	gran	gran	PROPN
fnp-2819	26	17	et	et	PROPN
fnp-2819	26	18	al	al	PROPN
fnp-2819	26	19	.	.	PROPN
fnp-2819	26	20	,	,	PUNCT
fnp-2819	26	21	2004	2004	NUM
fnp-2819	26	22	)	)	PUNCT
fnp-2819	26	23	,	,	PUNCT
fnp-2819	26	24	il-18	il-18	PUNCT
fnp-2819	26	25	(	(	PUNCT
fnp-2819	26	26	lalor	lalor	NOUN
fnp-2819	26	27	et	et	PROPN
fnp-2819	26	28	al	al	PROPN
fnp-2819	26	29	.	.	PROPN
fnp-2819	26	30	,	,	PUNCT
fnp-2819	26	31	2011	2011	NUM
fnp-2819	26	32	)	)	PUNCT
fnp-2819	26	33	,	,	PUNCT
fnp-2819	26	34	and	and	CCONJ
fnp-2819	26	35	il-23	il-23	NOUN
fnp-2819	26	36	(	(	PUNCT
fnp-2819	26	37	kreymborg	kreymborg	PROPN
fnp-2819	26	38	et	et	PROPN
fnp-2819	26	39	al	al	PROPN
fnp-2819	26	40	.	.	PROPN
fnp-2819	26	41	,	,	PUNCT
fnp-2819	26	42	2007	2007	NUM
fnp-2819	26	43	;	;	PUNCT
fnp-2819	26	44	el	el	PROPN
fnp-2819	26	45	-	-	PUNCT
fnp-2819	26	46	behi	behi	PROPN
fnp-2819	26	47	et	et	NOUN
fnp-2819	26	48	al	al	PROPN
fnp-2819	26	49	.	.	PROPN
fnp-2819	26	50	,	,	PUNCT
fnp-2819	26	51	2011	2011	NUM
fnp-2819	26	52	)	)	PUNCT
fnp-2819	26	53	critical	critical	ADJ
fnp-2819	26	54	for	for	ADP
fnp-2819	26	55	the	the	DET
fnp-2819	26	56	generation	generation	NOUN
fnp-2819	26	57	of	of	ADP
fnp-2819	26	58	th17	th17	NOUN
fnp-2819	26	59	cells	cell	NOUN
fnp-2819	26	60	were	be	AUX
fnp-2819	26	61	implicated	implicate	VERB
fnp-2819	26	62	in	in	ADP
fnp-2819	26	63	eae	eae	PROPN
fnp-2819	26	64	.	.	PUNCT
fnp-2819	27	1	the	the	DET
fnp-2819	27	2	roles	role	NOUN
fnp-2819	27	3	of	of	ADP
fnp-2819	27	4	the	the	DET
fnp-2819	27	5	pluripotent	pluripotent	ADJ
fnp-2819	27	6	cytokines	cytokine	NOUN
fnp-2819	27	7	,	,	PUNCT
fnp-2819	27	8	namely	namely	ADV
fnp-2819	27	9	the	the	DET
fnp-2819	27	10	tumor	tumor	NOUN
fnp-2819	27	11	necrosis	necrosis	NOUN
fnp-2819	27	12	factor	factor	NOUN
fnp-2819	27	13	-	-	PUNCT
fnp-2819	27	14	α	α	X
fnp-2819	27	15	(	(	PUNCT
fnp-2819	27	16	tnf	tnf	PROPN
fnp-2819	27	17	-	-	PUNCT
fnp-2819	27	18	α	α	NOUN
fnp-2819	27	19	)	)	PUNCT
fnp-2819	27	20	(	(	PUNCT
fnp-2819	27	21	hidaka	hidaka	X
fnp-2819	27	22	et	et	PROPN
fnp-2819	27	23	al	al	PROPN
fnp-2819	27	24	.	.	PROPN
fnp-2819	27	25	,	,	PUNCT
fnp-2819	27	26	2014	2014	NUM
fnp-2819	27	27	;	;	PUNCT
fnp-2819	27	28	borjini	borjini	NOUN
fnp-2819	27	29	et	et	PROPN
fnp-2819	27	30	al	al	PROPN
fnp-2819	27	31	.	.	PROPN
fnp-2819	27	32	,	,	PUNCT
fnp-2819	27	33	2016	2016	NUM
fnp-2819	27	34	)	)	PUNCT
fnp-2819	27	35	and	and	CCONJ
fnp-2819	27	36	granulocyte	granulocyte	ADJ
fnp-2819	27	37	-	-	PUNCT
fnp-2819	27	38	macrophage	macrophage	ADJ
fnp-2819	27	39	-	-	PUNCT
fnp-2819	27	40	colony	colony	NOUN
fnp-2819	27	41	-	-	PUNCT
fnp-2819	27	42	stimulating	stimulate	VERB
fnp-2819	27	43	factor	factor	NOUN
fnp-2819	27	44	(	(	PUNCT
fnp-2819	27	45	gm	gm	NOUN
fnp-2819	27	46	-	-	PUNCT
fnp-2819	27	47	csf	csf	PROPN
fnp-2819	27	48	/	/	SYM
fnp-2819	27	49	csf2	csf2	PROPN
fnp-2819	27	50	)	)	PUNCT
fnp-2819	27	51	(	(	PUNCT
fnp-2819	27	52	mcqualter	mcqualter	NOUN
fnp-2819	27	53	et	et	PROPN
fnp-2819	27	54	al	al	PROPN
fnp-2819	27	55	.	.	PROPN
fnp-2819	27	56	,	,	PUNCT
fnp-2819	27	57	2001	2001	NUM
fnp-2819	27	58	)	)	PUNCT
fnp-2819	27	59	were	be	AUX
fnp-2819	27	60	also	also	ADV
fnp-2819	27	61	studied	study	VERB
fnp-2819	27	62	in	in	ADP
fnp-2819	27	63	eae	eae	PROPN
fnp-2819	27	64	.	.	PUNCT
fnp-2819	28	1	in	in	ADP
fnp-2819	28	2	addition	addition	NOUN
fnp-2819	28	3	to	to	ADP
fnp-2819	28	4	the	the	DET
fnp-2819	28	5	adaptive	adaptive	ADJ
fnp-2819	28	6	immune	immune	ADJ
fnp-2819	28	7	system	system	NOUN
fnp-2819	28	8	,	,	PUNCT
fnp-2819	28	9	the	the	DET
fnp-2819	28	10	innate	innate	ADJ
fnp-2819	28	11	immune	immune	ADJ
fnp-2819	28	12	cells	cell	NOUN
fnp-2819	28	13	such	such	ADJ
fnp-2819	28	14	as	as	ADP
fnp-2819	28	15	neutrophils	neutrophil	NOUN
fnp-2819	28	16	(	(	PUNCT
fnp-2819	28	17	jayaraman	jayaraman	NOUN
fnp-2819	28	18	et	et	PROPN
fnp-2819	28	19	al	al	PROPN
fnp-2819	28	20	.	.	PROPN
fnp-2819	28	21	,	,	PUNCT
fnp-2819	28	22	2018	2018	NUM
fnp-2819	28	23	)	)	PUNCT
fnp-2819	28	24	,	,	PUNCT
fnp-2819	28	25	and	and	CCONJ
fnp-2819	28	26	the	the	DET
fnp-2819	28	27	cns	cns	NOUN
fnp-2819	28	28	-	-	PUNCT
fnp-2819	28	29	resident	resident	NOUN
fnp-2819	28	30	microglia	microglia	NOUN
fnp-2819	28	31	and	and	CCONJ
fnp-2819	28	32	astrocytes	astrocyte	NOUN
fnp-2819	28	33	(	(	PUNCT
fnp-2819	28	34	tran	tran	NOUN
fnp-2819	28	35	et	et	PROPN
fnp-2819	28	36	al	al	PROPN
fnp-2819	28	37	.	.	PROPN
fnp-2819	28	38	,	,	PUNCT
fnp-2819	28	39	1997	1997	NUM
fnp-2819	28	40	)	)	PUNCT
fnp-2819	28	41	appear	appear	VERB
fnp-2819	28	42	to	to	PART
fnp-2819	28	43	contribute	contribute	VERB
fnp-2819	28	44	to	to	ADP
fnp-2819	28	45	eae	eae	PROPN
fnp-2819	28	46	.	.	PUNCT
fnp-2819	29	1	interestingly	interestingly	ADV
fnp-2819	29	2	,	,	PUNCT
fnp-2819	29	3	the	the	DET
fnp-2819	29	4	first	first	ADJ
fnp-2819	29	5	described	describe	VERB
fnp-2819	29	6	and	and	CCONJ
fnp-2819	29	7	phylogenetically	phylogenetically	ADV
fnp-2819	29	8	conserved	conserve	VERB
fnp-2819	29	9	pluripotent	pluripotent	NOUN
fnp-2819	29	10	cytokine	cytokine	NOUN
fnp-2819	29	11	,	,	PUNCT
fnp-2819	29	12	the	the	DET
fnp-2819	29	13	migration	migration	NOUN
fnp-2819	29	14	inhibitory	inhibitory	ADJ
fnp-2819	29	15	factor	factor	NOUN
fnp-2819	29	16	(	(	PUNCT
fnp-2819	29	17	mif	mif	PROPN
fnp-2819	29	18	)	)	PUNCT
fnp-2819	29	19	(	(	PUNCT
fnp-2819	29	20	jayaraman	jayaraman	NOUN
fnp-2819	29	21	and	and	CCONJ
fnp-2819	29	22	muthukkaruppan	muthukkaruppan	NOUN
fnp-2819	29	23	,	,	PUNCT
fnp-2819	29	24	1977	1977	NUM
fnp-2819	29	25	)	)	PUNCT
fnp-2819	29	26	,	,	PUNCT
fnp-2819	29	27	has	have	AUX
fnp-2819	29	28	been	be	AUX
fnp-2819	29	29	implicated	implicate	VERB
fnp-2819	29	30	in	in	ADP
fnp-2819	29	31	ms	ms	PROPN
fnp-2819	29	32	(	(	PUNCT
fnp-2819	29	33	niino	niino	PROPN
fnp-2819	29	34	et	et	PROPN
fnp-2819	29	35	al	al	PROPN
fnp-2819	29	36	.	.	PROPN
fnp-2819	29	37	,	,	PUNCT
fnp-2819	29	38	2000	2000	NUM
fnp-2819	29	39	)	)	PUNCT
fnp-2819	29	40	and	and	CCONJ
fnp-2819	29	41	eae	eae	PROPN
fnp-2819	29	42	(	(	PUNCT
fnp-2819	29	43	powell	powell	PROPN
fnp-2819	29	44	et	et	PROPN
fnp-2819	29	45	al	al	PROPN
fnp-2819	29	46	.	.	PROPN
fnp-2819	29	47	,	,	PUNCT
fnp-2819	29	48	2005	2005	NUM
fnp-2819	29	49	)	)	PUNCT
fnp-2819	29	50	.	.	PUNCT
fnp-2819	30	1	other	other	ADJ
fnp-2819	30	2	determinants	determinant	NOUN
fnp-2819	30	3	critical	critical	ADJ
fnp-2819	30	4	for	for	ADP
fnp-2819	30	5	eae	eae	PROPN
fnp-2819	30	6	include	include	VERB
fnp-2819	30	7	the	the	DET
fnp-2819	30	8	orphan	orphan	NOUN
fnp-2819	30	9	receptor	receptor	NOUN
fnp-2819	30	10	,	,	PUNCT
fnp-2819	30	11	aryl	aryl	NOUN
fnp-2819	30	12	hydrocarbon	hydrocarbon	NOUN
fnp-2819	30	13	receptor	receptor	NOUN
fnp-2819	30	14	(	(	PUNCT
fnp-2819	30	15	ahr	ahr	PROPN
fnp-2819	30	16	)	)	PUNCT
fnp-2819	30	17	(	(	PUNCT
fnp-2819	30	18	nakahama	nakahama	NOUN
fnp-2819	30	19	et	et	PROPN
fnp-2819	30	20	al	al	PROPN
fnp-2819	30	21	.	.	PROPN
fnp-2819	30	22	,	,	PUNCT
fnp-2819	30	23	2017	2017	NUM
fnp-2819	30	24	)	)	PUNCT
fnp-2819	30	25	,	,	PUNCT
fnp-2819	30	26	the	the	DET
fnp-2819	30	27	transcription	transcription	NOUN
fnp-2819	30	28	factors	factor	NOUN
fnp-2819	30	29	eomesodermin	eomesodermin	VERB
fnp-2819	30	30	(	(	PUNCT
fnp-2819	30	31	eomes	eomes	PROPN
fnp-2819	30	32	)	)	PUNCT
fnp-2819	30	33	(	(	PUNCT
fnp-2819	30	34	raveney	raveney	NOUN
fnp-2819	30	35	et	et	PROPN
fnp-2819	30	36	al	al	PROPN
fnp-2819	30	37	.	.	PROPN
fnp-2819	30	38	,	,	PUNCT
fnp-2819	30	39	2015	2015	NUM
fnp-2819	30	40	)	)	PUNCT
fnp-2819	30	41	and	and	CCONJ
fnp-2819	30	42	declin-1	declin-1	PROPN
fnp-2819	30	43	(	(	PUNCT
fnp-2819	30	44	dec1	dec1	PROPN
fnp-2819	30	45	/	/	SYM
fnp-2819	30	46	bhlhe40	bhlhe40	ADV
fnp-2819	30	47	)	)	PUNCT
fnp-2819	31	1	(	(	PUNCT
fnp-2819	31	2	lin	lin	PROPN
fnp-2819	31	3	et	et	PROPN
fnp-2819	31	4	al	al	PROPN
fnp-2819	31	5	.	.	PROPN
fnp-2819	31	6	,	,	PUNCT
fnp-2819	31	7	2016	2016	NUM
fnp-2819	31	8	)	)	PUNCT
fnp-2819	31	9	,	,	PUNCT
fnp-2819	31	10	the	the	DET
fnp-2819	31	11	immunoregulatory	immunoregulatory	ADJ
fnp-2819	31	12	molecule	molecule	NOUN
fnp-2819	31	13	cd39	cd39	PROPN
fnp-2819	31	14	(	(	PUNCT
fnp-2819	31	15	mascanfroni	mascanfroni	VERB
fnp-2819	31	16	et	et	PROPN
fnp-2819	31	17	al	al	PROPN
fnp-2819	31	18	.	.	PROPN
fnp-2819	31	19	,	,	PUNCT
fnp-2819	31	20	2013	2013	NUM
fnp-2819	31	21	)	)	PUNCT
fnp-2819	31	22	,	,	PUNCT
fnp-2819	31	23	matrix	matrix	NOUN
fnp-2819	31	24	metalloproteinases	metalloproteinase	NOUN
fnp-2819	31	25	(	(	PUNCT
fnp-2819	31	26	mmp	mmp	PROPN
fnp-2819	31	27	)	)	PUNCT
fnp-2819	31	28	(	(	PUNCT
fnp-2819	31	29	kandagaddala	kandagaddala	PROPN
fnp-2819	31	30	et	et	PROPN
fnp-2819	31	31	al	al	PROPN
fnp-2819	31	32	.	.	PROPN
fnp-2819	31	33	,	,	PUNCT
fnp-2819	31	34	2012	2012	NUM
fnp-2819	31	35	;	;	PUNCT
fnp-2819	31	36	rempe	rempe	NOUN
fnp-2819	31	37	et	et	PROPN
fnp-2819	31	38	al	al	PROPN
fnp-2819	31	39	.	.	PROPN
fnp-2819	31	40	,	,	PUNCT
fnp-2819	31	41	2016	2016	NUM
fnp-2819	31	42	)	)	PUNCT
fnp-2819	31	43	,	,	PUNCT
fnp-2819	31	44	and	and	CCONJ
fnp-2819	31	45	the	the	DET
fnp-2819	31	46	chemokine	chemokine	ADJ
fnp-2819	31	47	ccl2	ccl2	PROPN
fnp-2819	31	48	(	(	PUNCT
fnp-2819	31	49	mahad	mahad	PROPN
fnp-2819	31	50	et	et	PROPN
fnp-2819	31	51	al	al	PROPN
fnp-2819	31	52	.	.	PROPN
fnp-2819	31	53	,	,	PUNCT
fnp-2819	31	54	2003	2003	NUM
fnp-2819	31	55	;	;	PUNCT
fnp-2819	31	56	moreno	moreno	PROPN
fnp-2819	31	57	et	et	PROPN
fnp-2819	31	58	al	al	PROPN
fnp-2819	31	59	.	.	PROPN
fnp-2819	31	60	,	,	PUNCT
fnp-2819	31	61	2014	2014	NUM
fnp-2819	31	62	;	;	PUNCT
fnp-2819	31	63	hidaka	hidaka	PROPN
fnp-2819	31	64	et	et	PROPN
fnp-2819	31	65	al	al	PROPN
fnp-2819	31	66	.	.	PROPN
fnp-2819	31	67	,	,	PUNCT
fnp-2819	31	68	2014	2014	NUM
fnp-2819	31	69	)	)	PUNCT
fnp-2819	31	70	.	.	PUNCT
fnp-2819	32	1	the	the	DET
fnp-2819	32	2	caveat	caveat	NOUN
fnp-2819	32	3	is	be	AUX
fnp-2819	32	4	the	the	DET
fnp-2819	32	5	lack	lack	NOUN
fnp-2819	32	6	of	of	ADP
fnp-2819	32	7	consensus	consensus	NOUN
fnp-2819	32	8	regarding	regard	VERB
fnp-2819	32	9	the	the	DET
fnp-2819	32	10	critical	critical	ADJ
fnp-2819	32	11	gene(s	gene(s	NOUN
fnp-2819	32	12	)	)	PUNCT
fnp-2819	32	13	involved	involve	VERB
fnp-2819	32	14	in	in	ADP
fnp-2819	32	15	eae	eae	PROPN
fnp-2819	32	16	.	.	PUNCT
fnp-2819	33	1	variations	variation	NOUN
fnp-2819	33	2	including	include	VERB
fnp-2819	33	3	the	the	DET
fnp-2819	33	4	genetic	genetic	ADJ
fnp-2819	33	5	background	background	NOUN
fnp-2819	33	6	of	of	ADP
fnp-2819	33	7	experimental	experimental	ADJ
fnp-2819	33	8	animals	animal	NOUN
fnp-2819	33	9	(	(	PUNCT
fnp-2819	33	10	rats	rat	NOUN
fnp-2819	33	11	and	and	CCONJ
fnp-2819	33	12	mice	mouse	NOUN
fnp-2819	33	13	)	)	PUNCT
fnp-2819	33	14	,	,	PUNCT
fnp-2819	33	15	types	type	NOUN
fnp-2819	33	16	of	of	ADP
fnp-2819	33	17	eae	eae	PROPN
fnp-2819	33	18	models	model	NOUN
fnp-2819	33	19	studied	study	VERB
fnp-2819	33	20	(	(	PUNCT
fnp-2819	33	21	short	short	ADJ
fnp-2819	33	22	-	-	PUNCT
fnp-2819	33	23	term	term	NOUN
fnp-2819	33	24	,	,	PUNCT
fnp-2819	33	25	self	self	NOUN
fnp-2819	33	26	-	-	PUNCT
fnp-2819	33	27	resolving	resolve	VERB
fnp-2819	33	28	‘	'	PUNCT
fnp-2819	33	29	classic	classic	ADJ
fnp-2819	33	30	’	'	PUNCT
fnp-2819	33	31	eae	eae	PROPN
fnp-2819	33	32	,	,	PUNCT
fnp-2819	33	33	‘	'	PUNCT
fnp-2819	33	34	atypical	atypical	ADJ
fnp-2819	33	35	’	'	PUNCT
fnp-2819	33	36	eae	eae	NOUN
fnp-2819	33	37	,	,	PUNCT
fnp-2819	33	38	relapsing	relapse	VERB
fnp-2819	33	39	-	-	PUNCT
fnp-2819	33	40	remitting	remit	VERB
fnp-2819	33	41	eae	eae	NOUN
fnp-2819	33	42	,	,	PUNCT
fnp-2819	33	43	and	and	CCONJ
fnp-2819	33	44	peae	peae	PROPN
fnp-2819	33	45	)	)	PUNCT
fnp-2819	33	46	,	,	PUNCT
fnp-2819	33	47	the	the	DET
fnp-2819	33	48	immunogens	immunogen	NOUN
fnp-2819	33	49	used	use	VERB
fnp-2819	33	50	for	for	ADP
fnp-2819	33	51	eae	eae	PROPN
fnp-2819	33	52	elicitation	elicitation	NOUN
fnp-2819	33	53	(	(	PUNCT
fnp-2819	33	54	whole	whole	ADJ
fnp-2819	33	55	spinal	spinal	ADJ
fnp-2819	33	56	cord	cord	NOUN
fnp-2819	33	57	homogenates	homogenate	NOUN
fnp-2819	33	58	,	,	PUNCT
fnp-2819	33	59	peptides	peptide	NOUN
fnp-2819	33	60	derived	derive	VERB
fnp-2819	33	61	from	from	ADP
fnp-2819	33	62	mog	mog	PROPN
fnp-2819	33	63	,	,	PUNCT
fnp-2819	33	64	mbp	mbp	NOUN
fnp-2819	33	65	and	and	CCONJ
fnp-2819	33	66	plp	plp	NOUN
fnp-2819	33	67	)	)	PUNCT
fnp-2819	33	68	,	,	PUNCT
fnp-2819	33	69	tissues	tissue	NOUN
fnp-2819	33	70	(	(	PUNCT
fnp-2819	33	71	cns	cns	X
fnp-2819	33	72	vs.	vs.	ADP
fnp-2819	33	73	peripheral	peripheral	ADJ
fnp-2819	33	74	lymphoid	lymphoid	ADJ
fnp-2819	33	75	cells	cell	NOUN
fnp-2819	33	76	)	)	PUNCT
fnp-2819	33	77	and	and	CCONJ
fnp-2819	33	78	the	the	DET
fnp-2819	33	79	time	time	NOUN
fnp-2819	33	80	points	point	NOUN
fnp-2819	33	81	(	(	PUNCT
fnp-2819	33	82	peak	peak	NOUN
fnp-2819	33	83	vs.	vs.	X
fnp-2819	33	84	chronic	chronic	ADJ
fnp-2819	33	85	phase	phase	NOUN
fnp-2819	33	86	)	)	PUNCT
fnp-2819	33	87	examined	examine	VERB
fnp-2819	33	88	can	can	AUX
fnp-2819	33	89	contribute	contribute	VERB
fnp-2819	33	90	to	to	ADP
fnp-2819	33	91	the	the	DET
fnp-2819	33	92	uncertainty	uncertainty	NOUN
fnp-2819	33	93	of	of	ADP
fnp-2819	33	94	the	the	DET
fnp-2819	33	95	results	result	NOUN
fnp-2819	33	96	.	.	PUNCT
fnp-2819	34	1	hence	hence	ADV
fnp-2819	34	2	,	,	PUNCT
fnp-2819	34	3	investigation	investigation	NOUN
fnp-2819	34	4	of	of	ADP
fnp-2819	34	5	the	the	DET
fnp-2819	34	6	roles	role	NOUN
fnp-2819	34	7	of	of	ADP
fnp-2819	34	8	these	these	DET
fnp-2819	34	9	various	various	ADJ
fnp-2819	34	10	immune	immune	ADJ
fnp-2819	34	11	response	response	NOUN
fnp-2819	34	12	-	-	PUNCT
fnp-2819	34	13	related	relate	VERB
fnp-2819	34	14	genes	gene	NOUN
fnp-2819	34	15	in	in	ADP
fnp-2819	34	16	a	a	DET
fnp-2819	34	17	well	well	ADV
fnp-2819	34	18	-	-	PUNCT
fnp-2819	34	19	characterized	characterize	VERB
fnp-2819	34	20	model	model	NOUN
fnp-2819	34	21	is	be	AUX
fnp-2819	34	22	likely	likely	ADJ
fnp-2819	34	23	to	to	PART
fnp-2819	34	24	yield	yield	VERB
fnp-2819	34	25	crucial	crucial	ADJ
fnp-2819	34	26	information	information	NOUN
fnp-2819	34	27	on	on	ADP
fnp-2819	34	28	the	the	DET
fnp-2819	34	29	impact	impact	NOUN
fnp-2819	34	30	of	of	ADP
fnp-2819	34	31	these	these	DET
fnp-2819	34	32	genes	gene	NOUN
fnp-2819	34	33	on	on	ADP
fnp-2819	34	34	neurodegeneration	neurodegeneration	NOUN
fnp-2819	34	35	.	.	PUNCT
fnp-2819	35	1	our	our	PRON
fnp-2819	35	2	previous	previous	ADJ
fnp-2819	35	3	work	work	NOUN
fnp-2819	35	4	demonstrated	demonstrate	VERB
fnp-2819	35	5	that	that	SCONJ
fnp-2819	35	6	the	the	DET
fnp-2819	35	7	treatment	treatment	NOUN
fnp-2819	35	8	of	of	ADP
fnp-2819	35	9	mog35	mog35	NOUN
fnp-2819	35	10	-	-	PUNCT
fnp-2819	35	11	55	55	NUM
fnp-2819	35	12	immunized	immunize	VERB
fnp-2819	35	13	female	female	ADJ
fnp-2819	35	14	nod	nod	NOUN
fnp-2819	35	15	mice	mouse	NOUN
fnp-2819	35	16	with	with	ADP
fnp-2819	35	17	the	the	DET
fnp-2819	35	18	most	most	ADV
fnp-2819	35	19	potent	potent	ADJ
fnp-2819	35	20	histone	histone	NOUN
fnp-2819	35	21	deacetylase	deacetylase	PROPN
fnp-2819	35	22	(	(	PUNCT
fnp-2819	35	23	hdac	hdac	NOUN
fnp-2819	35	24	)	)	PUNCT
fnp-2819	35	25	inhibitor	inhibitor	NOUN
fnp-2819	35	26	trichostatin	trichostatin	NOUN
fnp-2819	35	27	a	a	DET
fnp-2819	35	28	(	(	PUNCT
fnp-2819	35	29	tsa	tsa	PROPN
fnp-2819	35	30	)	)	PUNCT
fnp-2819	35	31	(	(	PUNCT
fnp-2819	35	32	de	de	X
fnp-2819	35	33	ruijter	ruijter	NOUN
fnp-2819	35	34	et	et	PROPN
fnp-2819	35	35	al	al	PROPN
fnp-2819	35	36	.	.	PROPN
fnp-2819	35	37	,	,	PUNCT
fnp-2819	35	38	2003	2003	NUM
fnp-2819	35	39	)	)	PUNCT
fnp-2819	35	40	improved	improve	VERB
fnp-2819	35	41	the	the	DET
fnp-2819	35	42	clinical	clinical	ADJ
fnp-2819	35	43	symptoms	symptom	NOUN
fnp-2819	35	44	of	of	ADP
fnp-2819	35	45	peae	peae	PROPN
fnp-2819	35	46	(	(	PUNCT
fnp-2819	35	47	jayaraman	jayaraman	PROPN
fnp-2819	35	48	et	et	PROPN
fnp-2819	35	49	al	al	PROPN
fnp-2819	35	50	.	.	PROPN
fnp-2819	35	51	,	,	PUNCT
fnp-2819	35	52	2017	2017	NUM
fnp-2819	35	53	)	)	PUNCT
fnp-2819	35	54	.	.	PUNCT
fnp-2819	36	1	protection	protection	NOUN
fnp-2819	36	2	from	from	ADP
fnp-2819	36	3	peae	peae	PROPN
fnp-2819	36	4	was	be	AUX
fnp-2819	36	5	accompanied	accompany	VERB
fnp-2819	36	6	by	by	ADP
fnp-2819	36	7	histone	histone	NOUN
fnp-2819	36	8	h3	h3	NOUN
fnp-2819	36	9	hyperacetylation	hyperacetylation	NOUN
fnp-2819	36	10	in	in	ADP
fnp-2819	36	11	the	the	DET
fnp-2819	36	12	spinal	spinal	ADJ
fnp-2819	36	13	cord	cord	NOUN
fnp-2819	36	14	(	(	PUNCT
fnp-2819	36	15	sc	sc	PROPN
fnp-2819	36	16	)	)	PUNCT
fnp-2819	36	17	and	and	CCONJ
fnp-2819	36	18	spleen	spleen	PROPN
fnp-2819	36	19	,	,	PUNCT
fnp-2819	36	20	reduced	reduce	VERB
fnp-2819	36	21	influx	influx	NOUN
fnp-2819	36	22	of	of	ADP
fnp-2819	36	23	t	t	NOUN
fnp-2819	36	24	cells	cell	NOUN
fnp-2819	36	25	,	,	PUNCT
fnp-2819	36	26	and	and	CCONJ
fnp-2819	36	27	neutrophils	neutrophil	NOUN
fnp-2819	36	28	into	into	ADP
fnp-2819	36	29	the	the	DET
fnp-2819	36	30	cns	cns	NOUN
fnp-2819	36	31	as	as	ADV
fnp-2819	36	32	well	well	ADV
fnp-2819	36	33	as	as	ADP
fnp-2819	36	34	diminished	diminish	VERB
fnp-2819	36	35	axonal	axonal	ADJ
fnp-2819	36	36	damage	damage	NOUN
fnp-2819	36	37	of	of	ADP
fnp-2819	36	38	the	the	DET
fnp-2819	36	39	neurons	neuron	NOUN
fnp-2819	36	40	in	in	ADP
fnp-2819	36	41	the	the	DET
fnp-2819	36	42	cns	cns	NOUN
fnp-2819	36	43	(	(	PUNCT
fnp-2819	36	44	jayaraman	jayaraman	NOUN
fnp-2819	36	45	et	et	PROPN
fnp-2819	36	46	al	al	PROPN
fnp-2819	36	47	.	.	PROPN
fnp-2819	36	48	,	,	PUNCT
fnp-2819	36	49	2017	2017	NUM
fnp-2819	36	50	;	;	PUNCT
fnp-2819	36	51	2018	2018	NUM
fnp-2819	36	52	)	)	PUNCT
fnp-2819	36	53	.	.	PUNCT
fnp-2819	37	1	to	to	PART
fnp-2819	37	2	gain	gain	VERB
fnp-2819	37	3	insights	insight	NOUN
fnp-2819	37	4	into	into	ADP
fnp-2819	37	5	the	the	DET
fnp-2819	37	6	roles	role	NOUN
fnp-2819	37	7	of	of	ADP
fnp-2819	37	8	various	various	ADJ
fnp-2819	37	9	genes	gene	NOUN
fnp-2819	37	10	in	in	ADP
fnp-2819	37	11	the	the	DET
fnp-2819	37	12	peae	peae	PROPN
fnp-2819	37	13	model	model	NOUN
fnp-2819	37	14	,	,	PUNCT
fnp-2819	37	15	we	we	PRON
fnp-2819	37	16	studied	study	VERB
fnp-2819	37	17	the	the	DET
fnp-2819	37	18	expression	expression	NOUN
fnp-2819	37	19	profiles	profile	NOUN
fnp-2819	37	20	of	of	ADP
fnp-2819	37	21	41	41	NUM
fnp-2819	37	22	genes	gene	NOUN
fnp-2819	37	23	encoding	encode	VERB
fnp-2819	37	24	lymphokines	lymphokine	NOUN
fnp-2819	37	25	,	,	PUNCT
fnp-2819	37	26	transcription	transcription	NOUN
fnp-2819	37	27	factors	factor	NOUN
fnp-2819	37	28	,	,	PUNCT
fnp-2819	37	29	accessory	accessory	ADJ
fnp-2819	37	30	cell	cell	NOUN
fnp-2819	37	31	-	-	PUNCT
fnp-2819	37	32	associated	associate	VERB
fnp-2819	37	33	determinants	determinant	NOUN
fnp-2819	37	34	,	,	PUNCT
fnp-2819	37	35	and	and	CCONJ
fnp-2819	37	36	chemokines	chemokine	NOUN
fnp-2819	37	37	in	in	ADP
fnp-2819	37	38	the	the	DET
fnp-2819	37	39	cns	cns	NOUN
fnp-2819	37	40	and	and	CCONJ
fnp-2819	37	41	secondary	secondary	ADJ
fnp-2819	37	42	lymphoid	lymphoid	ADJ
fnp-2819	37	43	organs	organ	NOUN
fnp-2819	37	44	(	(	PUNCT
fnp-2819	37	45	slo	slo	PROPN
fnp-2819	37	46	)	)	PUNCT
fnp-2819	37	47	longitudinally	longitudinally	ADV
fnp-2819	37	48	during	during	ADP
fnp-2819	37	49	the	the	DET
fnp-2819	37	50	prolonged	prolonged	ADJ
fnp-2819	37	51	course	course	NOUN
fnp-2819	37	52	of	of	ADP
fnp-2819	37	53	the	the	DET
fnp-2819	37	54	disease	disease	NOUN
fnp-2819	37	55	(	(	PUNCT
fnp-2819	37	56	27	27	NUM
fnp-2819	37	57	-	-	PUNCT
fnp-2819	37	58	weeks	week	NOUN
fnp-2819	37	59	)	)	PUNCT
fnp-2819	37	60	.	.	PUNCT
fnp-2819	38	1	surprisingly	surprisingly	ADV
fnp-2819	38	2	,	,	PUNCT
fnp-2819	38	3	only	only	ADV
fnp-2819	38	4	a	a	DET
fnp-2819	38	5	small	small	ADJ
fnp-2819	38	6	set	set	NOUN
fnp-2819	38	7	of	of	ADP
fnp-2819	38	8	mostly	mostly	ADV
fnp-2819	38	9	non	non	ADJ
fnp-2819	38	10	-	-	ADJ
fnp-2819	38	11	overlapping	overlapping	ADJ
fnp-2819	38	12	genes	gene	NOUN
fnp-2819	38	13	were	be	AUX
fnp-2819	38	14	differentially	differentially	ADV
fnp-2819	38	15	upregulated	upregulate	VERB
fnp-2819	38	16	in	in	ADP
fnp-2819	38	17	the	the	DET
fnp-2819	38	18	cns	cns	PROPN
fnp-2819	38	19	and	and	CCONJ
fnp-2819	38	20	slo	slo	PROPN
fnp-2819	38	21	,	,	PUNCT
fnp-2819	38	22	which	which	PRON
fnp-2819	38	23	were	be	AUX
fnp-2819	38	24	substantially	substantially	ADV
fnp-2819	38	25	repressed	repress	VERB
fnp-2819	38	26	by	by	ADP
fnp-2819	38	27	tsa	tsa	NOUN
fnp-2819	38	28	treatment	treatment	NOUN
fnp-2819	38	29	,	,	PUNCT
fnp-2819	38	30	indicating	indicate	VERB
fnp-2819	38	31	their	their	PRON
fnp-2819	38	32	possible	possible	ADJ
fnp-2819	38	33	roles	role	NOUN
fnp-2819	38	34	in	in	ADP
fnp-2819	38	35	peae	peae	PROPN
fnp-2819	38	36	.	.	PUNCT
fnp-2819	39	1	these	these	DET
fnp-2819	39	2	data	datum	NOUN
fnp-2819	39	3	suggest	suggest	VERB
fnp-2819	39	4	that	that	SCONJ
fnp-2819	39	5	similar	similar	ADJ
fnp-2819	39	6	perturbation	perturbation	NOUN
fnp-2819	39	7	of	of	ADP
fnp-2819	39	8	the	the	DET
fnp-2819	39	9	epigenome	epigenome	NOUN
fnp-2819	39	10	of	of	ADP
fnp-2819	39	11	ms	ms	NOUN
fnp-2819	39	12	patients	patient	NOUN
fnp-2819	39	13	may	may	AUX
fnp-2819	39	14	facilitate	facilitate	VERB
fnp-2819	39	15	the	the	DET
fnp-2819	39	16	identification	identification	NOUN
fnp-2819	39	17	of	of	ADP
fnp-2819	39	18	molecular	molecular	ADJ
fnp-2819	39	19	targets	target	NOUN
fnp-2819	39	20	for	for	ADP
fnp-2819	39	21	the	the	DET
fnp-2819	39	22	development	development	NOUN
fnp-2819	39	23	of	of	ADP
fnp-2819	39	24	novel	novel	ADJ
fnp-2819	39	25	drugs	drug	NOUN
fnp-2819	39	26	to	to	PART
fnp-2819	39	27	treat	treat	VERB
fnp-2819	39	28	this	this	DET
fnp-2819	39	29	debilitating	debilitate	VERB
fnp-2819	39	30	disease	disease	NOUN
fnp-2819	39	31	.	.	PUNCT
fnp-2819	40	1	2	2	X
fnp-2819	40	2	.	.	X
fnp-2819	40	3	material	material	NOUN
fnp-2819	40	4	and	and	CCONJ
fnp-2819	40	5	methods	method	NOUN
fnp-2819	40	6	2.1	2.1	NUM
fnp-2819	40	7	.	.	PUNCT
fnp-2819	41	1	eae	eae	PROPN
fnp-2819	41	2	induction	induction	NOUN
fnp-2819	41	3	and	and	CCONJ
fnp-2819	41	4	treatment	treatment	NOUN
fnp-2819	41	5	this	this	DET
fnp-2819	41	6	study	study	NOUN
fnp-2819	41	7	was	be	AUX
fnp-2819	41	8	approved	approve	VERB
fnp-2819	41	9	by	by	ADP
fnp-2819	41	10	the	the	DET
fnp-2819	41	11	institutional	institutional	ADJ
fnp-2819	41	12	animal	animal	NOUN
fnp-2819	41	13	care	care	NOUN
fnp-2819	41	14	and	and	CCONJ
fnp-2819	41	15	use	use	VERB
fnp-2819	41	16	committee	committee	NOUN
fnp-2819	41	17	of	of	ADP
fnp-2819	41	18	the	the	DET
fnp-2819	41	19	university	university	PROPN
fnp-2819	41	20	of	of	ADP
fnp-2819	41	21	illinois	illinois	PROPN
fnp-2819	41	22	at	at	ADP
fnp-2819	41	23	chicago	chicago	PROPN
fnp-2819	41	24	and	and	CCONJ
fnp-2819	41	25	conducted	conduct	VERB
fnp-2819	41	26	according	accord	VERB
fnp-2819	41	27	to	to	ADP
fnp-2819	41	28	the	the	DET
fnp-2819	41	29	national	national	PROPN
fnp-2819	41	30	institutes	institutes	PROPN
fnp-2819	41	31	of	of	ADP
fnp-2819	41	32	health	health	NOUN
fnp-2819	41	33	guide	guide	NOUN
fnp-2819	41	34	for	for	ADP
fnp-2819	41	35	the	the	DET
fnp-2819	41	36	care	care	NOUN
fnp-2819	41	37	and	and	CCONJ
fnp-2819	41	38	use	use	NOUN
fnp-2819	41	39	of	of	ADP
fnp-2819	41	40	laboratory	laboratory	NOUN
fnp-2819	41	41	animals	animal	NOUN
fnp-2819	41	42	(	(	PUNCT
fnp-2819	41	43	nih	nih	PROPN
fnp-2819	41	44	publications	publication	NOUN
fnp-2819	41	45	no	no	PRON
fnp-2819	41	46	.	.	NOUN
fnp-2819	41	47	8023	8023	NUM
fnp-2819	41	48	,	,	PUNCT
fnp-2819	41	49	revised	revise	VERB
fnp-2819	41	50	1978	1978	NUM
fnp-2819	41	51	)	)	PUNCT
fnp-2819	41	52	.	.	PUNCT
fnp-2819	42	1	female	female	PROPN
fnp-2819	42	2	nod	nod	PROPN
fnp-2819	42	3	/	/	SYM
fnp-2819	42	4	shiltj	shiltj	NOUN
fnp-2819	42	5	mice	mouse	NOUN
fnp-2819	42	6	were	be	AUX
fnp-2819	42	7	purchased	purchase	VERB
fnp-2819	42	8	from	from	ADP
fnp-2819	42	9	the	the	DET
fnp-2819	42	10	jackson	jackson	PROPN
fnp-2819	42	11	laboratories	laboratory	NOUN
fnp-2819	42	12	(	(	PUNCT
fnp-2819	42	13	bar	bar	NOUN
fnp-2819	42	14	harbor	harbor	NOUN
fnp-2819	42	15	,	,	PUNCT
fnp-2819	42	16	me	i	PRON
fnp-2819	42	17	)	)	PUNCT
fnp-2819	42	18	and	and	CCONJ
fnp-2819	42	19	immunized	immunize	VERB
fnp-2819	42	20	subcutaneously	subcutaneously	ADV
fnp-2819	42	21	(	(	PUNCT
fnp-2819	42	22	s.c	s.c	PROPN
fnp-2819	42	23	)	)	PUNCT
fnp-2819	42	24	on	on	ADP
fnp-2819	42	25	the	the	DET
fnp-2819	42	26	flank	flank	NOUN
fnp-2819	42	27	with	with	ADP
fnp-2819	42	28	100	100	NUM
fnp-2819	42	29	µg	µg	NOUN
fnp-2819	42	30	of	of	ADP
fnp-2819	42	31	mouse	mouse	NOUN
fnp-2819	42	32	mog35	mog35	NOUN
fnp-2819	42	33	-	-	PUNCT
fnp-2819	42	34	55	55	NUM
fnp-2819	42	35	peptide	peptide	NOUN
fnp-2819	42	36	(	(	PUNCT
fnp-2819	42	37	tocris	tocris	NOUN
fnp-2819	42	38	bioscience	bioscience	PROPN
fnp-2819	42	39	)	)	PUNCT
fnp-2819	42	40	emulsified	emulsify	VERB
fnp-2819	42	41	in	in	ADP
fnp-2819	42	42	complete	complete	ADJ
fnp-2819	42	43	freund	freund	NOUN
fnp-2819	42	44	's	's	PART
fnp-2819	42	45	adjuvant	adjuvant	NOUN
fnp-2819	42	46	and	and	CCONJ
fnp-2819	42	47	pertussis	pertussis	NOUN
fnp-2819	42	48	toxin	toxin	NOUN
fnp-2819	42	49	was	be	AUX
fnp-2819	42	50	administered	administer	VERB
fnp-2819	42	51	intravenously	intravenously	ADV
fnp-2819	42	52	(	(	PUNCT
fnp-2819	42	53	jayaraman	jayaraman	PROPN
fnp-2819	42	54	et	et	PROPN
fnp-2819	42	55	al	al	PROPN
fnp-2819	42	56	.	.	PROPN
fnp-2819	42	57	,	,	PUNCT
fnp-2819	42	58	2017	2017	NUM
fnp-2819	42	59	;	;	PUNCT
fnp-2819	42	60	2018	2018	NUM
fnp-2819	42	61	)	)	PUNCT
fnp-2819	42	62	.	.	PUNCT
fnp-2819	43	1	randomly	randomly	ADV
fnp-2819	43	2	chosen	choose	VERB
fnp-2819	43	3	littermates	littermate	NOUN
fnp-2819	43	4	were	be	AUX
fnp-2819	43	5	injected	inject	VERB
fnp-2819	43	6	s.c	s.c	PROPN
fnp-2819	43	7	on	on	ADP
fnp-2819	43	8	the	the	DET
fnp-2819	43	9	flank	flank	NOUN
fnp-2819	43	10	with	with	ADP
fnp-2819	43	11	500	500	NUM
fnp-2819	43	12	µg	µg	NOUN
fnp-2819	43	13	of	of	ADP
fnp-2819	43	14	tsa	tsa	NOUN
fnp-2819	43	15	(	(	PUNCT
fnp-2819	43	16	sigma	sigma	PROPN
fnp-2819	43	17	chemical	chemical	PROPN
fnp-2819	43	18	company	company	PROPN
fnp-2819	43	19	,	,	PUNCT
fnp-2819	43	20	st	st	PROPN
fnp-2819	43	21	.	.	PROPN
fnp-2819	43	22	louis	louis	PROPN
fnp-2819	43	23	,	,	PUNCT
fnp-2819	43	24	mo	mo	NOUN
fnp-2819	43	25	)	)	PUNCT
fnp-2819	43	26	per	per	ADP
fnp-2819	43	27	kg	kg	X
fnp-2819	43	28	body	body	NOUN
fnp-2819	43	29	weight	weight	NOUN
fnp-2819	43	30	three	three	NUM
fnp-2819	43	31	times	time	NOUN
fnp-2819	43	32	a	a	DET
fnp-2819	43	33	week	week	NOUN
fnp-2819	43	34	.	.	PUNCT
fnp-2819	44	1	controls	control	NOUN
fnp-2819	44	2	received	receive	VERB
fnp-2819	44	3	the	the	DET
fnp-2819	44	4	same	same	ADJ
fnp-2819	44	5	amount	amount	NOUN
fnp-2819	44	6	of	of	ADP
fnp-2819	44	7	the	the	DET
fnp-2819	44	8	vehicle	vehicle	NOUN
fnp-2819	44	9	,	,	PUNCT
fnp-2819	44	10	dimethyl	dimethyl	NOUN
fnp-2819	44	11	sulfoxide	sulfoxide	NOUN
fnp-2819	44	12	(	(	PUNCT
fnp-2819	44	13	dmso	dmso	PROPN
fnp-2819	44	14	)	)	PUNCT
fnp-2819	44	15	(	(	PUNCT
fnp-2819	44	16	sigma	sigma	PROPN
fnp-2819	44	17	)	)	PUNCT
fnp-2819	44	18	diluted	dilute	VERB
fnp-2819	44	19	in	in	ADP
fnp-2819	44	20	phosphate	phosphate	NOUN
fnp-2819	44	21	-	-	PUNCT
fnp-2819	44	22	buffered	buffer	VERB
fnp-2819	44	23	saline	saline	NOUN
fnp-2819	44	24	(	(	PUNCT
fnp-2819	44	25	pbs	pbs	PROPN
fnp-2819	44	26	)	)	PUNCT
fnp-2819	44	27	.	.	PUNCT
fnp-2819	45	1	the	the	DET
fnp-2819	45	2	body	body	NOUN
fnp-2819	45	3	weight	weight	NOUN
fnp-2819	45	4	,	,	PUNCT
fnp-2819	45	5	blood	blood	NOUN
fnp-2819	45	6	glucose	glucose	NOUN
fnp-2819	45	7	levels	level	NOUN
fnp-2819	45	8	,	,	PUNCT
fnp-2819	45	9	(	(	PUNCT
fnp-2819	45	10	jayaraman	jayaraman	NOUN
fnp-2819	45	11	et	et	PROPN
fnp-2819	45	12	al	al	PROPN
fnp-2819	45	13	.	.	PROPN
fnp-2819	45	14	,	,	PUNCT
fnp-2819	45	15	2010	2010	NUM
fnp-2819	45	16	;	;	PUNCT
fnp-2819	45	17	2013	2013	NUM
fnp-2819	45	18	;	;	PUNCT
fnp-2819	45	19	jayaraman	jayaraman	NOUN
fnp-2819	45	20	and	and	CCONJ
fnp-2819	45	21	jayaraman	jayaraman	NOUN
fnp-2819	45	22	,	,	PUNCT
fnp-2819	45	23	2018	2018	NUM
fnp-2819	45	24	;	;	PUNCT
fnp-2819	45	25	patel	patel	PROPN
fnp-2819	45	26	et	et	PROPN
fnp-2819	45	27	al	al	PROPN
fnp-2819	45	28	.	.	PROPN
fnp-2819	45	29	,	,	PUNCT
fnp-2819	45	30	2011	2011	NUM
fnp-2819	45	31	)	)	PUNCT
fnp-2819	45	32	and	and	CCONJ
fnp-2819	45	33	clinical	clinical	ADJ
fnp-2819	45	34	scores	score	NOUN
fnp-2819	45	35	(	(	PUNCT
fnp-2819	45	36	jayaraman	jayaraman	NOUN
fnp-2819	45	37	et	et	PROPN
fnp-2819	45	38	al	al	PROPN
fnp-2819	45	39	.	.	PROPN
fnp-2819	45	40	,	,	PUNCT
fnp-2819	45	41	2017	2017	NUM
fnp-2819	45	42	;	;	PUNCT
fnp-2819	45	43	2018	2018	NUM
fnp-2819	45	44	)	)	PUNCT
fnp-2819	45	45	were	be	AUX
fnp-2819	45	46	recorded	record	VERB
fnp-2819	45	47	three	three	NUM
fnp-2819	45	48	times	time	NOUN
fnp-2819	45	49	a	a	DET
fnp-2819	45	50	week	week	NOUN
fnp-2819	45	51	.	.	PUNCT
fnp-2819	46	1	the	the	DET
fnp-2819	46	2	eae	eae	PROPN
fnp-2819	46	3	score	score	NOUN
fnp-2819	46	4	was	be	AUX
fnp-2819	46	5	assigned	assign	VERB
fnp-2819	46	6	as	as	SCONJ
fnp-2819	46	7	follows	follow	VERB
fnp-2819	46	8	:	:	PUNCT
fnp-2819	46	9	0	0	NUM
fnp-2819	46	10	,	,	PUNCT
fnp-2819	46	11	healthy	healthy	ADJ
fnp-2819	46	12	,	,	PUNCT
fnp-2819	46	13	1	1	NUM
fnp-2819	46	14	,	,	PUNCT
fnp-2819	46	15	limp	limp	ADJ
fnp-2819	46	16	tail	tail	NOUN
fnp-2819	46	17	,	,	PUNCT
fnp-2819	46	18	2	2	NUM
fnp-2819	46	19	,	,	PUNCT
fnp-2819	46	20	one	one	NUM
fnp-2819	46	21	hind	hind	NOUN
fnp-2819	46	22	limb	limb	NOUN
fnp-2819	46	23	weakness	weakness	NOUN
fnp-2819	46	24	,	,	PUNCT
fnp-2819	46	25	3	3	NUM
fnp-2819	46	26	,	,	PUNCT
fnp-2819	46	27	both	both	DET
fnp-2819	46	28	hind	hind	ADJ
fnp-2819	46	29	limb	limb	NOUN
fnp-2819	46	30	weakness	weakness	NOUN
fnp-2819	46	31	,	,	PUNCT
fnp-2819	46	32	4	4	NUM
fnp-2819	46	33	,	,	PUNCT
fnp-2819	46	34	forelimb	forelimb	ADJ
fnp-2819	46	35	weakness	weakness	NOUN
fnp-2819	46	36	,	,	PUNCT
fnp-2819	46	37	5	5	NUM
fnp-2819	46	38	,	,	PUNCT
fnp-2819	46	39	paralysis	paralysis	NOUN
fnp-2819	46	40	,	,	PUNCT
fnp-2819	46	41	moribund	moribund	ADJ
fnp-2819	46	42	or	or	CCONJ
fnp-2819	46	43	death	death	NOUN
fnp-2819	46	44	(	(	PUNCT
fnp-2819	46	45	jayaraman	jayaraman	NOUN
fnp-2819	46	46	et	et	PROPN
fnp-2819	46	47	al	al	PROPN
fnp-2819	46	48	.	.	PROPN
fnp-2819	46	49	,	,	PUNCT
fnp-2819	46	50	2017	2017	NUM
fnp-2819	46	51	;	;	PUNCT
fnp-2819	46	52	2018	2018	NUM
fnp-2819	46	53	)	)	PUNCT
fnp-2819	46	54	.	.	PUNCT
fnp-2819	47	1	five	five	NUM
fnp-2819	47	2	mice	mouse	NOUN
fnp-2819	47	3	per	per	ADP
fnp-2819	47	4	group	group	NOUN
fnp-2819	47	5	were	be	AUX
fnp-2819	47	6	chosen	choose	VERB
fnp-2819	47	7	based	base	VERB
fnp-2819	47	8	on	on	ADP
fnp-2819	47	9	our	our	PRON
fnp-2819	47	10	previous	previous	ADJ
fnp-2819	47	11	investigations	investigation	NOUN
fnp-2819	47	12	(	(	PUNCT
fnp-2819	47	13	jayaraman	jayaraman	NOUN
fnp-2819	47	14	et	et	PROPN
fnp-2819	47	15	al	al	PROPN
fnp-2819	47	16	.	.	PROPN
fnp-2819	47	17	,	,	PUNCT
fnp-2819	47	18	2017	2017	NUM
fnp-2819	47	19	;	;	PUNCT
fnp-2819	47	20	2018	2018	NUM
fnp-2819	47	21	)	)	PUNCT
fnp-2819	47	22	.	.	PUNCT
fnp-2819	48	1	the	the	DET
fnp-2819	48	2	data	datum	NOUN
fnp-2819	48	3	are	be	AUX
fnp-2819	48	4	presented	present	VERB
fnp-2819	48	5	as	as	ADP
fnp-2819	48	6	the	the	DET
fnp-2819	48	7	mean	mean	PROPN
fnp-2819	48	8	±	±	NUM
fnp-2819	48	9	sem	sem	NOUN
fnp-2819	48	10	for	for	ADP
fnp-2819	48	11	each	each	DET
fnp-2819	48	12	time	time	NOUN
fnp-2819	48	13	point	point	NOUN
fnp-2819	48	14	of	of	ADP
fnp-2819	48	15	observation	observation	NOUN
fnp-2819	48	16	.	.	PUNCT
fnp-2819	49	1	2.2	2.2	NUM
fnp-2819	49	2	.	.	PUNCT
fnp-2819	49	3	gene	gene	NOUN
fnp-2819	49	4	expression	expression	NOUN
fnp-2819	49	5	analysis	analysis	NOUN
fnp-2819	49	6	we	we	PRON
fnp-2819	49	7	analyzed	analyze	VERB
fnp-2819	49	8	the	the	DET
fnp-2819	49	9	expression	expression	NOUN
fnp-2819	49	10	levels	level	NOUN
fnp-2819	49	11	of	of	ADP
fnp-2819	49	12	41	41	NUM
fnp-2819	49	13	genes	gene	NOUN
fnp-2819	49	14	in	in	ADP
fnp-2819	49	15	the	the	DET
fnp-2819	49	16	entire	entire	ADJ
fnp-2819	49	17	sc	sc	NOUN
fnp-2819	49	18	and	and	CCONJ
fnp-2819	49	19	slo	slo	PROPN
fnp-2819	49	20	(	(	PUNCT
fnp-2819	49	21	spleen	spleen	PROPN
fnp-2819	49	22	and	and	CCONJ
fnp-2819	49	23	the	the	DET
fnp-2819	49	24	draining	drain	VERB
fnp-2819	49	25	inguinal	inguinal	ADJ
fnp-2819	49	26	,	,	PUNCT
fnp-2819	49	27	popliteal	popliteal	NOUN
fnp-2819	49	28	,	,	PUNCT
fnp-2819	49	29	axillary	axillary	ADJ
fnp-2819	49	30	and	and	CCONJ
fnp-2819	49	31	cervical	cervical	ADJ
fnp-2819	49	32	lymph	lymph	NOUN
fnp-2819	49	33	nodes	node	NOUN
fnp-2819	49	34	)	)	PUNCT
fnp-2819	49	35	of	of	ADP
fnp-2819	49	36	mice	mouse	NOUN
fnp-2819	49	37	that	that	PRON
fnp-2819	49	38	were	be	AUX
fnp-2819	49	39	immunized	immunize	VERB
fnp-2819	49	40	with	with	ADP
fnp-2819	49	41	mog35	mog35	NOUN
fnp-2819	49	42	-	-	PUNCT
fnp-2819	49	43	55	55	NUM
fnp-2819	49	44	and	and	CCONJ
fnp-2819	49	45	treated	treat	VERB
fnp-2819	49	46	with	with	ADP
fnp-2819	49	47	dmso	dmso	NOUN
fnp-2819	49	48	or	or	CCONJ
fnp-2819	49	49	tsa	tsa	NOUN
fnp-2819	49	50	.	.	PUNCT
fnp-2819	50	1	we	we	PRON
fnp-2819	50	2	have	have	AUX
fnp-2819	50	3	investigated	investigate	VERB
fnp-2819	50	4	60	60	NUM
fnp-2819	50	5	mice	mouse	NOUN
fnp-2819	50	6	(	(	PUNCT
fnp-2819	50	7	five	five	NUM
fnp-2819	50	8	mice	mouse	NOUN
fnp-2819	50	9	treated	treat	VERB
fnp-2819	50	10	with	with	ADP
fnp-2819	50	11	dmso	dmso	NOUN
fnp-2819	50	12	and	and	CCONJ
fnp-2819	50	13	five	five	NUM
fnp-2819	50	14	mice	mouse	NOUN
fnp-2819	50	15	with	with	ADP
fnp-2819	50	16	tsa	tsa	NOUN
fnp-2819	50	17	at	at	ADP
fnp-2819	50	18	six	six	NUM
fnp-2819	50	19	-	-	PUNCT
fnp-2819	50	20	time	time	NOUN
fnp-2819	50	21	points	point	NOUN
fnp-2819	50	22	)	)	PUNCT
fnp-2819	50	23	for	for	ADP
fnp-2819	50	24	the	the	DET
fnp-2819	50	25	expression	expression	NOUN
fnp-2819	50	26	of	of	ADP
fnp-2819	50	27	genes	gene	NOUN
fnp-2819	50	28	in	in	ADP
fnp-2819	50	29	the	the	DET
fnp-2819	50	30	sc	sc	PROPN
fnp-2819	50	31	and	and	CCONJ
fnp-2819	50	32	slo	slo	PROPN
fnp-2819	50	33	concurrently	concurrently	ADV
fnp-2819	50	34	.	.	PUNCT
fnp-2819	51	1	to	to	PART
fnp-2819	51	2	analyze	analyze	VERB
fnp-2819	51	3	the	the	DET
fnp-2819	51	4	effect	effect	NOUN
fnp-2819	51	5	of	of	ADP
fnp-2819	51	6	the	the	DET
fnp-2819	51	7	drug	drug	NOUN
fnp-2819	51	8	on	on	ADP
fnp-2819	51	9	the	the	DET
fnp-2819	51	10	basal	basal	ADJ
fnp-2819	51	11	level	level	NOUN
fnp-2819	51	12	of	of	ADP
fnp-2819	51	13	gene	gene	NOUN
fnp-2819	51	14	transcription	transcription	NOUN
fnp-2819	51	15	regardless	regardless	ADV
fnp-2819	51	16	of	of	ADP
fnp-2819	51	17	immunization	immunization	NOUN
fnp-2819	51	18	,	,	PUNCT
fnp-2819	51	19	we	we	PRON
fnp-2819	51	20	treated	treat	VERB
fnp-2819	51	21	separate	separate	ADJ
fnp-2819	51	22	groups	group	NOUN
fnp-2819	51	23	of	of	ADP
fnp-2819	51	24	10	10	NUM
fnp-2819	51	25	unimmunized	unimmunized	ADJ
fnp-2819	51	26	mice	mouse	NOUN
fnp-2819	51	27	with	with	ADP
fnp-2819	51	28	tsa	tsa	NOUN
fnp-2819	51	29	or	or	CCONJ
fnp-2819	51	30	dmso	dmso	NOUN
fnp-2819	51	31	and	and	CCONJ
fnp-2819	51	32	analyzed	analyze	VERB
fnp-2819	51	33	one	one	NUM
fnp-2819	51	34	day	day	NOUN
fnp-2819	51	35	later	later	ADV
fnp-2819	51	36	since	since	SCONJ
fnp-2819	51	37	tsa	tsa	NOUN
fnp-2819	51	38	acts	act	NOUN
fnp-2819	51	39	within	within	ADP
fnp-2819	51	40	hours	hour	NOUN
fnp-2819	51	41	of	of	ADP
fnp-2819	51	42	treatment	treatment	NOUN
fnp-2819	51	43	(	(	PUNCT
fnp-2819	51	44	van	van	PROPN
fnp-2819	51	45	lint	lint	NOUN
fnp-2819	51	46	et	et	PROPN
fnp-2819	51	47	al	al	PROPN
fnp-2819	51	48	.	.	PROPN
fnp-2819	51	49	,	,	PUNCT
fnp-2819	51	50	1996	1996	NUM
fnp-2819	51	51	;	;	PUNCT
fnp-2819	51	52	de	de	X
fnp-2819	51	53	ruijter	ruijter	NOUN
fnp-2819	51	54	et	et	PROPN
fnp-2819	51	55	al	al	PROPN
fnp-2819	51	56	.	.	PROPN
fnp-2819	51	57	,	,	PUNCT
fnp-2819	51	58	2003	2003	NUM
fnp-2819	51	59	)	)	PUNCT
fnp-2819	51	60	.	.	PUNCT
fnp-2819	52	1	these	these	DET
fnp-2819	52	2	data	datum	NOUN
fnp-2819	52	3	are	be	AUX
fnp-2819	52	4	indicated	indicate	VERB
fnp-2819	52	5	at	at	ADP
fnp-2819	52	6	the	the	DET
fnp-2819	52	7	day	day	NOUN
fnp-2819	52	8	1	1	NUM
fnp-2819	52	9	-	-	PUNCT
fnp-2819	52	10	time	time	NOUN
fnp-2819	52	11	point	point	NOUN
fnp-2819	52	12	in	in	ADP
fnp-2819	52	13	all	all	DET
fnp-2819	52	14	figures	figure	NOUN
fnp-2819	52	15	.	.	PUNCT
fnp-2819	53	1	on	on	ADP
fnp-2819	53	2	the	the	DET
fnp-2819	53	3	other	other	ADJ
fnp-2819	53	4	hand	hand	NOUN
fnp-2819	53	5	,	,	PUNCT
fnp-2819	53	6	treatment	treatment	NOUN
fnp-2819	53	7	groups	group	NOUN
fnp-2819	53	8	received	receive	VERB
fnp-2819	53	9	dmso	dmso	NOUN
fnp-2819	53	10	or	or	CCONJ
fnp-2819	53	11	tsa	tsa	NOUN
fnp-2819	53	12	starting	start	VERB
fnp-2819	53	13	from	from	ADP
fnp-2819	53	14	the	the	DET
fnp-2819	53	15	day	day	NOUN
fnp-2819	53	16	of	of	ADP
fnp-2819	53	17	immunization	immunization	NOUN
fnp-2819	53	18	.	.	PUNCT
fnp-2819	54	1	mice	mouse	NOUN
fnp-2819	54	2	were	be	AUX
fnp-2819	54	3	perfused	perfuse	VERB
fnp-2819	54	4	with	with	ADP
fnp-2819	54	5	pbs	pbs	PROPN
fnp-2819	54	6	before	before	SCONJ
fnp-2819	54	7	the	the	DET
fnp-2819	54	8	spinal	spinal	ADJ
fnp-2819	54	9	cord	cord	NOUN
fnp-2819	54	10	was	be	AUX
fnp-2819	54	11	extracted	extract	VERB
fnp-2819	54	12	to	to	PART
fnp-2819	54	13	avoid	avoid	VERB
fnp-2819	54	14	peripheral	peripheral	ADJ
fnp-2819	54	15	blood	blood	NOUN
fnp-2819	54	16	contamination	contamination	NOUN
fnp-2819	54	17	(	(	PUNCT
fnp-2819	54	18	jayaraman	jayaraman	NOUN
fnp-2819	54	19	et	et	PROPN
fnp-2819	54	20	al	al	PROPN
fnp-2819	54	21	.	.	PROPN
fnp-2819	54	22	,	,	PUNCT
fnp-2819	54	23	2017	2017	NUM
fnp-2819	54	24	;	;	PUNCT
fnp-2819	54	25	2018	2018	NUM
fnp-2819	54	26	)	)	PUNCT
fnp-2819	54	27	.	.	PUNCT
fnp-2819	55	1	total	total	ADJ
fnp-2819	55	2	rna	rna	PROPN
fnp-2819	55	3	was	be	AUX
fnp-2819	55	4	isolated	isolate	VERB
fnp-2819	55	5	from	from	ADP
fnp-2819	55	6	individual	individual	ADJ
fnp-2819	55	7	mice	mouse	NOUN
fnp-2819	55	8	using	use	VERB
fnp-2819	55	9	trizol	trizol	PROPN
fnp-2819	55	10	(	(	PUNCT
fnp-2819	55	11	invitrogen	invitrogen	PROPN
fnp-2819	55	12	,	,	PUNCT
fnp-2819	55	13	carlsbad	carlsbad	PROPN
fnp-2819	55	14	,	,	PUNCT
fnp-2819	55	15	ca	ca	NOUN
fnp-2819	55	16	)	)	PUNCT
fnp-2819	55	17	.	.	PUNCT
fnp-2819	56	1	since	since	SCONJ
fnp-2819	56	2	preliminary	preliminary	ADJ
fnp-2819	56	3	experiments	experiment	NOUN
fnp-2819	56	4	indicated	indicate	VERB
fnp-2819	56	5	similar	similar	ADJ
fnp-2819	56	6	levels	level	NOUN
fnp-2819	56	7	of	of	ADP
fnp-2819	56	8	expression	expression	NOUN
fnp-2819	56	9	of	of	ADP
fnp-2819	56	10	genes	gene	NOUN
fnp-2819	56	11	among	among	ADP
fnp-2819	56	12	different	different	ADJ
fnp-2819	56	13	mice	mouse	NOUN
fnp-2819	56	14	in	in	ADP
fnp-2819	56	15	each	each	DET
fnp-2819	56	16	group	group	NOUN
fnp-2819	56	17	,	,	PUNCT
fnp-2819	56	18	the	the	DET
fnp-2819	56	19	rna	rna	NOUN
fnp-2819	56	20	from	from	ADP
fnp-2819	56	21	five	five	NUM
fnp-2819	56	22	mice	mouse	NOUN
fnp-2819	56	23	per	per	ADP
fnp-2819	56	24	group	group	NOUN
fnp-2819	56	25	at	at	ADP
fnp-2819	56	26	each	each	DET
fnp-2819	56	27	time	time	NOUN
fnp-2819	56	28	point	point	NOUN
fnp-2819	56	29	was	be	AUX
fnp-2819	56	30	pooled	pool	VERB
fnp-2819	56	31	from	from	ADP
fnp-2819	56	32	identical	identical	ADJ
fnp-2819	56	33	tissues	tissue	NOUN
fnp-2819	56	34	to	to	PART
fnp-2819	56	35	minimize	minimize	VERB
fnp-2819	56	36	individual	individual	ADJ
fnp-2819	56	37	variability	variability	NOUN
fnp-2819	56	38	,	,	PUNCT
fnp-2819	56	39	as	as	SCONJ
fnp-2819	56	40	described	describe	VERB
fnp-2819	56	41	previously	previously	ADV
fnp-2819	56	42	(	(	PUNCT
fnp-2819	56	43	jayaraman	jayaraman	NOUN
fnp-2819	56	44	et	et	PROPN
fnp-2819	56	45	al	al	PROPN
fnp-2819	56	46	.	.	PROPN
fnp-2819	56	47	,	,	PUNCT
fnp-2819	56	48	2013	2013	NUM
fnp-2819	56	49	)	)	PUNCT
fnp-2819	56	50	.	.	PUNCT
fnp-2819	57	1	the	the	DET
fnp-2819	57	2	rna	rna	NOUN
fnp-2819	57	3	was	be	AUX
fnp-2819	57	4	treated	treat	VERB
fnp-2819	57	5	with	with	ADP
fnp-2819	57	6	turbo	turbo	NOUN
fnp-2819	57	7	dnase	dnase	NOUN
fnp-2819	57	8	and	and	CCONJ
fnp-2819	57	9	converted	convert	VERB
fnp-2819	57	10	to	to	ADP
fnp-2819	57	11	cdna	cdna	PROPN
fnp-2819	57	12	using	use	VERB
fnp-2819	57	13	the	the	DET
fnp-2819	57	14	high	high	ADJ
fnp-2819	57	15	-	-	PUNCT
fnp-2819	57	16	capacity	capacity	NOUN
fnp-2819	57	17	cdna	cdna	NOUN
fnp-2819	57	18	reverse	reverse	NOUN
fnp-2819	57	19	transcription	transcription	NOUN
fnp-2819	57	20	kit	kit	NOUN
fnp-2819	57	21	(	(	PUNCT
fnp-2819	57	22	applied	apply	VERB
fnp-2819	57	23	biosystems	biosystem	NOUN
fnp-2819	57	24	,	,	PUNCT
fnp-2819	57	25	carlsbad	carlsbad	PROPN
fnp-2819	57	26	,	,	PUNCT
fnp-2819	57	27	ca	ca	NOUN
fnp-2819	57	28	)	)	PUNCT
fnp-2819	57	29	,	,	PUNCT
fnp-2819	57	30	as	as	SCONJ
fnp-2819	57	31	described	describe	VERB
fnp-2819	57	32	earlier	early	ADV
fnp-2819	57	33	(	(	PUNCT
fnp-2819	57	34	jayaraman	jayaraman	NOUN
fnp-2819	57	35	et	et	PROPN
fnp-2819	57	36	al	al	PROPN
fnp-2819	57	37	.	.	PROPN
fnp-2819	57	38	,	,	PUNCT
fnp-2819	57	39	2010	2010	NUM
fnp-2819	57	40	;	;	PUNCT
fnp-2819	57	41	2013	2013	NUM
fnp-2819	57	42	;	;	PUNCT
fnp-2819	57	43	2017	2017	NUM
fnp-2819	57	44	;	;	PUNCT
fnp-2819	57	45	2018	2018	NUM
fnp-2819	57	46	;	;	PUNCT
fnp-2819	58	1	patel	patel	PROPN
fnp-2819	58	2	et	et	PROPN
fnp-2819	58	3	al	al	PROPN
fnp-2819	58	4	.	.	PROPN
fnp-2819	58	5	,	,	PUNCT
fnp-2819	58	6	2011	2011	NUM
fnp-2819	58	7	)	)	PUNCT
fnp-2819	58	8	.	.	PUNCT
fnp-2819	59	1	real	real	ADJ
fnp-2819	59	2	-	-	PUNCT
fnp-2819	59	3	time	time	NOUN
fnp-2819	59	4	quantitative	quantitative	ADJ
fnp-2819	59	5	reverse	reverse	NOUN
fnp-2819	59	6	-	-	PUNCT
fnp-2819	59	7	transcriptase	transcriptase	NOUN
fnp-2819	59	8	mediated	mediate	VERB
fnp-2819	59	9	polymerase	polymerase	NOUN
fnp-2819	59	10	chain	chain	NOUN
fnp-2819	59	11	reaction	reaction	NOUN
fnp-2819	59	12	(	(	PUNCT
fnp-2819	59	13	qrt	qrt	NOUN
fnp-2819	59	14	-	-	PUNCT
fnp-2819	59	15	pcr	pcr	NOUN
fnp-2819	59	16	)	)	PUNCT
fnp-2819	59	17	was	be	AUX
fnp-2819	59	18	performed	perform	VERB
fnp-2819	59	19	using	use	VERB
fnp-2819	59	20	the	the	DET
fnp-2819	59	21	applied	apply	VERB
fnp-2819	59	22	biosystems	biosystem	NOUN
fnp-2819	59	23	viia7	viia7	PROPN
fnp-2819	60	1	real	real	ADJ
fnp-2819	60	2	-	-	PUNCT
fnp-2819	60	3	time	time	NOUN
fnp-2819	60	4	pcr	pcr	ADJ
fnp-2819	60	5	system	system	NOUN
fnp-2819	60	6	.	.	PUNCT
fnp-2819	61	1	the	the	DET
fnp-2819	61	2	cdna	cdna	PROPN
fnp-2819	61	3	equivalent	equivalent	NOUN
fnp-2819	61	4	to	to	ADP
fnp-2819	61	5	100	100	NUM
fnp-2819	61	6	ng	ng	PROPN
fnp-2819	61	7	of	of	ADP
fnp-2819	61	8	total	total	ADJ
fnp-2819	61	9	rna	rna	NOUN
fnp-2819	61	10	was	be	AUX
fnp-2819	61	11	used	use	VERB
fnp-2819	61	12	along	along	ADP
fnp-2819	61	13	with	with	ADP
fnp-2819	61	14	the	the	DET
fnp-2819	61	15	2x	2x	NUM
fnp-2819	61	16	sybr	sybr	X
fnp-2819	61	17	green	green	ADJ
fnp-2819	61	18	master	master	NOUN
fnp-2819	61	19	mix	mix	NOUN
fnp-2819	61	20	in	in	ADP
fnp-2819	61	21	the	the	DET
fnp-2819	61	22	qrt	qrt	NOUN
fnp-2819	61	23	-	-	PUNCT
fnp-2819	61	24	pcr	pcr	NOUN
fnp-2819	61	25	assay	assay	NOUN
fnp-2819	61	26	.	.	PUNCT
fnp-2819	62	1	the	the	DET
fnp-2819	62	2	primer	primer	NOUN
fnp-2819	62	3	sets	set	NOUN
fnp-2819	62	4	were	be	AUX
fnp-2819	62	5	designed	design	VERB
fnp-2819	62	6	,	,	PUNCT
fnp-2819	62	7	and	and	CCONJ
fnp-2819	62	8	specificity	specificity	NOUN
fnp-2819	62	9	validated	validate	VERB
fnp-2819	62	10	using	use	VERB
fnp-2819	62	11	the	the	DET
fnp-2819	62	12	primer3	primer3	ADJ
fnp-2819	62	13	and	and	CCONJ
fnp-2819	62	14	blast	blast	NOUN
fnp-2819	62	15	programs	program	NOUN
fnp-2819	62	16	(	(	PUNCT
fnp-2819	62	17	ncbi.nim.nih.gov	ncbi.nim.nih.gov	NOUN
fnp-2819	62	18	)	)	PUNCT
fnp-2819	62	19	and	and	CCONJ
fnp-2819	62	20	bisearch	bisearch	NOUN
fnp-2819	62	21	web	web	NOUN
fnp-2819	62	22	server	server	NOUN
fnp-2819	62	23	tool	tool	NOUN
fnp-2819	62	24	(	(	PUNCT
fnp-2819	62	25	bisearch.enzim.hu	bisearch.enzim.hu	PROPN
fnp-2819	62	26	)	)	PUNCT
fnp-2819	62	27	.	.	PUNCT
fnp-2819	63	1	the	the	DET
fnp-2819	63	2	mif	mif	PROPN
fnp-2819	63	3	primer	primer	NOUN
fnp-2819	63	4	sets	set	NOUN
fnp-2819	63	5	were	be	AUX
fnp-2819	63	6	purchased	purchase	VERB
fnp-2819	63	7	from	from	ADP
fnp-2819	63	8	the	the	DET
fnp-2819	63	9	integrated	integrate	VERB
fnp-2819	63	10	dna	dna	PROPN
fnp-2819	63	11	technologies	technology	NOUN
fnp-2819	63	12	(	(	PUNCT
fnp-2819	63	13	coralville	coralville	NOUN
fnp-2819	63	14	,	,	PUNCT
fnp-2819	63	15	ia	ia	PROPN
fnp-2819	63	16	)	)	PUNCT
fnp-2819	63	17	,	,	PUNCT
fnp-2819	63	18	and	and	CCONJ
fnp-2819	63	19	the	the	DET
fnp-2819	63	20	custom	custom	NOUN
fnp-2819	63	21	primers	primer	NOUN
fnp-2819	63	22	were	be	AUX
fnp-2819	63	23	synthesized	synthesize	VERB
fnp-2819	63	24	at	at	ADP
fnp-2819	63	25	the	the	DET
fnp-2819	63	26	same	same	ADJ
fnp-2819	63	27	facility	facility	NOUN
fnp-2819	63	28	.	.	PUNCT
fnp-2819	64	1	whereas	whereas	SCONJ
fnp-2819	64	2	the	the	DET
fnp-2819	64	3	primer	primer	NOUN
fnp-2819	64	4	sets	set	VERB
fnp-2819	64	5	for	for	ADP
fnp-2819	64	6	gapdh	gapdh	NOUN
fnp-2819	64	7	,	,	PUNCT
fnp-2819	64	8	il4	il4	PROPN
fnp-2819	64	9	,	,	PUNCT
fnp-2819	64	10	il17a	il17a	PROPN
fnp-2819	64	11	,	,	PUNCT
fnp-2819	64	12	il18	il18	PROPN
fnp-2819	64	13	,	,	PUNCT
fnp-2819	64	14	ifng	ifng	NOUN
fnp-2819	64	15	,	,	PUNCT
fnp-2819	64	16	nos2	nos2	PROPN
fnp-2819	64	17	,	,	PUNCT
fnp-2819	64	18	tnfa	tnfa	PRON
fnp-2819	64	19	,	,	PUNCT
fnp-2819	64	20	tbet	tbet	NOUN
fnp-2819	64	21	,	,	PUNCT
fnp-2819	64	22	rorgt	rorgt	NOUN
fnp-2819	64	23	,	,	PUNCT
fnp-2819	64	24	and	and	CCONJ
fnp-2819	64	25	gata3	gata3	NOUN
fnp-2819	64	26	were	be	AUX
fnp-2819	64	27	described	describe	VERB
fnp-2819	64	28	previously	previously	ADV
fnp-2819	64	29	(	(	PUNCT
fnp-2819	64	30	jayaraman	jayaraman	NOUN
fnp-2819	64	31	et	et	PROPN
fnp-2819	64	32	al	al	PROPN
fnp-2819	64	33	.	.	PROPN
fnp-2819	64	34	,	,	PUNCT
fnp-2819	64	35	2010	2010	NUM
fnp-2819	64	36	;	;	PUNCT
fnp-2819	64	37	2013	2013	NUM
fnp-2819	64	38	)	)	PUNCT
fnp-2819	64	39	,	,	PUNCT
fnp-2819	64	40	other	other	ADJ
fnp-2819	64	41	primer	primer	NOUN
fnp-2819	64	42	sets	set	NOUN
fnp-2819	64	43	are	be	AUX
fnp-2819	64	44	listed	list	VERB
fnp-2819	64	45	in	in	ADP
fnp-2819	64	46	supplementary	supplementary	ADJ
fnp-2819	64	47	table	table	NOUN
fnp-2819	64	48	1	1	NUM
fnp-2819	64	49	.	.	PUNCT
fnp-2819	65	1	every	every	DET
fnp-2819	65	2	cdna	cdna	PROPN
fnp-2819	65	3	sample	sample	NOUN
fnp-2819	65	4	was	be	AUX
fnp-2819	65	5	analyzed	analyze	VERB
fnp-2819	65	6	in	in	ADP
fnp-2819	65	7	triplicate	triplicate	NOUN
fnp-2819	65	8	at	at	ADP
fnp-2819	65	9	each	each	DET
fnp-2819	65	10	time	time	NOUN
fnp-2819	65	11	point	point	NOUN
fnp-2819	65	12	,	,	PUNCT
fnp-2819	65	13	and	and	CCONJ
fnp-2819	65	14	the	the	DET
fnp-2819	65	15	expression	expression	NOUN
fnp-2819	65	16	level	level	NOUN
fnp-2819	65	17	of	of	ADP
fnp-2819	65	18	any	any	DET
fnp-2819	65	19	given	give	VERB
fnp-2819	65	20	gene	gene	NOUN
fnp-2819	65	21	was	be	AUX
fnp-2819	65	22	ascertained	ascertain	VERB
fnp-2819	65	23	using	use	VERB
fnp-2819	65	24	gapdh	gapdh	NOUN
fnp-2819	65	25	as	as	ADP
fnp-2819	65	26	the	the	DET
fnp-2819	65	27	normalizer	normalizer	NOUN
fnp-2819	65	28	(	(	PUNCT
fnp-2819	65	29	jayaraman	jayaraman	PROPN
fnp-2819	65	30	et	et	PROPN
fnp-2819	65	31	al	al	PROPN
fnp-2819	65	32	.	.	PROPN
fnp-2819	65	33	,	,	PUNCT
fnp-2819	65	34	2010	2010	NUM
fnp-2819	65	35	;	;	PUNCT
fnp-2819	65	36	2013	2013	NUM
fnp-2819	65	37	;	;	PUNCT
fnp-2819	65	38	2017	2017	NUM
fnp-2819	65	39	;	;	PUNCT
fnp-2819	65	40	2018	2018	NUM
fnp-2819	65	41	;	;	PUNCT
fnp-2819	65	42	patel	patel	PROPN
fnp-2819	65	43	et	et	PROPN
fnp-2819	65	44	al	al	PROPN
fnp-2819	65	45	.	.	PROPN
fnp-2819	65	46	,	,	PUNCT
fnp-2819	65	47	2011	2011	NUM
fnp-2819	65	48	)	)	PUNCT
fnp-2819	65	49	since	since	SCONJ
fnp-2819	65	50	it	it	PRON
fnp-2819	65	51	was	be	AUX
fnp-2819	65	52	not	not	PART
fnp-2819	65	53	altered	alter	VERB
fnp-2819	65	54	by	by	ADP
fnp-2819	65	55	tsa	tsa	NOUN
fnp-2819	65	56	treatment	treatment	NOUN
fnp-2819	65	57	in	in	ADP
fnp-2819	65	58	vitro	vitro	X
fnp-2819	65	59	(	(	PUNCT
fnp-2819	65	60	van	van	NOUN
fnp-2819	65	61	lint	lint	NOUN
fnp-2819	65	62	et	et	PROPN
fnp-2819	65	63	al	al	PROPN
fnp-2819	65	64	.	.	PROPN
fnp-2819	65	65	,	,	PUNCT
fnp-2819	65	66	1996	1996	NUM
fnp-2819	65	67	)	)	PUNCT
fnp-2819	65	68	.	.	PUNCT
fnp-2819	66	1	the	the	DET
fnp-2819	66	2	same	same	ADJ
fnp-2819	66	3	cdna	cdna	PROPN
fnp-2819	66	4	pool	pool	NOUN
fnp-2819	66	5	was	be	AUX
fnp-2819	66	6	analyzed	analyze	VERB
fnp-2819	66	7	for	for	ADP
fnp-2819	66	8	the	the	DET
fnp-2819	66	9	expression	expression	NOUN
fnp-2819	66	10	levels	level	NOUN
fnp-2819	66	11	of	of	ADP
fnp-2819	66	12	all	all	DET
fnp-2819	66	13	41	41	NUM
fnp-2819	66	14	genes	gene	NOUN
fnp-2819	66	15	.	.	PUNCT
fnp-2819	67	1	the	the	DET
fnp-2819	67	2	gene	gene	NOUN
fnp-2819	67	3	expression	expression	NOUN
fnp-2819	67	4	level	level	NOUN
fnp-2819	67	5	was	be	AUX
fnp-2819	67	6	determined	determine	VERB
fnp-2819	67	7	using	use	VERB
fnp-2819	67	8	the	the	DET
fnp-2819	67	9	2-∆∆ct	2-∆∆ct	PROPN
fnp-2819	67	10	method	method	NOUN
fnp-2819	67	11	(	(	PUNCT
fnp-2819	67	12	jayaraman	jayaraman	NOUN
fnp-2819	67	13	et	et	PROPN
fnp-2819	67	14	al	al	PROPN
fnp-2819	67	15	.	.	PROPN
fnp-2819	67	16	,	,	PUNCT
fnp-2819	67	17	2010	2010	NUM
fnp-2819	67	18	;	;	PUNCT
fnp-2819	67	19	2013	2013	NUM
fnp-2819	67	20	;	;	PUNCT
fnp-2819	67	21	2017	2017	NUM
fnp-2819	67	22	;	;	PUNCT
fnp-2819	67	23	2018	2018	NUM
fnp-2819	67	24	;	;	PUNCT
fnp-2819	67	25	patel	patel	PROPN
fnp-2819	67	26	et	et	PROPN
fnp-2819	67	27	al	al	PROPN
fnp-2819	67	28	.	.	PROPN
fnp-2819	67	29	,	,	PUNCT
fnp-2819	67	30	2011	2011	NUM
fnp-2819	67	31	)	)	PUNCT
fnp-2819	67	32	.	.	PUNCT
fnp-2819	68	1	the	the	DET
fnp-2819	68	2	data	datum	NOUN
fnp-2819	68	3	are	be	AUX
fnp-2819	68	4	represented	represent	VERB
fnp-2819	68	5	as	as	ADP
fnp-2819	68	6	the	the	DET
fnp-2819	68	7	mean	mean	PROPN
fnp-2819	68	8	±	±	NUM
fnp-2819	68	9	sem	sem	NOUN
fnp-2819	68	10	of	of	ADP
fnp-2819	68	11	triplicate	triplicate	VERB
fnp-2819	68	12	technical	technical	ADJ
fnp-2819	68	13	repeats	repeat	NOUN
fnp-2819	68	14	per	per	ADP
fnp-2819	68	15	time	time	NOUN
fnp-2819	68	16	point	point	NOUN
fnp-2819	68	17	.	.	PUNCT
fnp-2819	69	1	the	the	DET
fnp-2819	69	2	outliers	outlier	NOUN
fnp-2819	69	3	that	that	PRON
fnp-2819	69	4	deviated	deviate	VERB
fnp-2819	69	5	>	>	X
fnp-2819	69	6	10	10	NUM
fnp-2819	69	7	%	%	NOUN
fnp-2819	69	8	from	from	ADP
fnp-2819	69	9	other	other	ADJ
fnp-2819	69	10	data	datum	NOUN
fnp-2819	69	11	points	point	NOUN
fnp-2819	69	12	were	be	AUX
fnp-2819	69	13	omitted	omit	VERB
fnp-2819	69	14	,	,	PUNCT
fnp-2819	69	15	and	and	CCONJ
fnp-2819	69	16	the	the	DET
fnp-2819	69	17	samples	sample	NOUN
fnp-2819	69	18	reanalyzed	reanalyze	VERB
fnp-2819	69	19	for	for	ADP
fnp-2819	69	20	gene	gene	NOUN
fnp-2819	69	21	expression	expression	NOUN
fnp-2819	69	22	.	.	PUNCT
fnp-2819	70	1	2.3	2.3	NUM
fnp-2819	70	2	.	.	PUNCT
fnp-2819	70	3	elisa	elisa	PROPN
fnp-2819	70	4	sera	sera	NOUN
fnp-2819	70	5	were	be	AUX
fnp-2819	70	6	collected	collect	VERB
fnp-2819	70	7	from	from	ADP
fnp-2819	70	8	naïve	naïve	ADJ
fnp-2819	70	9	and	and	CCONJ
fnp-2819	70	10	immunized	immunize	VERB
fnp-2819	70	11	mice	mouse	NOUN
fnp-2819	70	12	with	with	ADP
fnp-2819	70	13	or	or	CCONJ
fnp-2819	70	14	without	without	ADP
fnp-2819	70	15	tsa	tsa	NOUN
fnp-2819	70	16	treatment	treatment	NOUN
fnp-2819	70	17	and	and	CCONJ
fnp-2819	70	18	assayed	assayed	ADJ
fnp-2819	70	19	for	for	ADP
fnp-2819	70	20	ccl2	ccl2	NOUN
fnp-2819	70	21	using	use	VERB
fnp-2819	70	22	the	the	DET
fnp-2819	70	23	elisa	elisa	NOUN
fnp-2819	70	24	ready	ready	ADJ
fnp-2819	70	25	-	-	PUNCT
fnp-2819	70	26	set	set	NOUN
fnp-2819	70	27	-	-	PUNCT
fnp-2819	70	28	go	go	NOUN
fnp-2819	70	29	kit	kit	NOUN
fnp-2819	70	30	(	(	PUNCT
fnp-2819	70	31	ebioscience	ebioscience	PROPN
fnp-2819	70	32	,	,	PUNCT
fnp-2819	70	33	san	san	PROPN
fnp-2819	70	34	diego	diego	PROPN
fnp-2819	70	35	,	,	PUNCT
fnp-2819	70	36	ca	ca	NOUN
fnp-2819	70	37	)	)	PUNCT
fnp-2819	70	38	.	.	PUNCT
fnp-2819	71	1	samples	sample	NOUN
fnp-2819	71	2	were	be	AUX
fnp-2819	71	3	pooled	pool	VERB
fnp-2819	71	4	from	from	ADP
fnp-2819	71	5	five	five	NUM
fnp-2819	71	6	mice	mouse	NOUN
fnp-2819	71	7	per	per	ADP
fnp-2819	71	8	group	group	NOUN
fnp-2819	71	9	,	,	PUNCT
fnp-2819	71	10	analyzed	analyze	VERB
fnp-2819	71	11	in	in	ADP
fnp-2819	71	12	duplicate	duplicate	NOUN
fnp-2819	71	13	,	,	PUNCT
fnp-2819	71	14	and	and	CCONJ
fnp-2819	71	15	expressed	express	VERB
fnp-2819	71	16	per	per	ADP
fnp-2819	71	17	mg	mg	PROPN
fnp-2819	71	18	of	of	ADP
fnp-2819	71	19	protein	protein	NOUN
fnp-2819	71	20	.	.	PUNCT
fnp-2819	72	1	2.4	2.4	NUM
fnp-2819	72	2	.	.	PUNCT
fnp-2819	73	1	statistics	statistic	NOUN
fnp-2819	73	2	the	the	DET
fnp-2819	73	3	statistical	statistical	ADJ
fnp-2819	73	4	significance	significance	NOUN
fnp-2819	73	5	of	of	ADP
fnp-2819	73	6	clinical	clinical	ADJ
fnp-2819	73	7	scores	score	NOUN
fnp-2819	73	8	between	between	ADP
fnp-2819	73	9	control	control	NOUN
fnp-2819	73	10	and	and	CCONJ
fnp-2819	73	11	tsa	tsa	NOUN
fnp-2819	73	12	-	-	PUNCT
fnp-2819	73	13	treated	treat	VERB
fnp-2819	73	14	groups	group	NOUN
fnp-2819	73	15	was	be	AUX
fnp-2819	73	16	determined	determine	VERB
fnp-2819	73	17	using	use	VERB
fnp-2819	73	18	the	the	DET
fnp-2819	73	19	area	area	NOUN
fnp-2819	73	20	under	under	ADP
fnp-2819	73	21	the	the	DET
fnp-2819	73	22	roc	roc	PROPN
fnp-2819	73	23	curve	curve	NOUN
fnp-2819	73	24	.	.	PUNCT
fnp-2819	74	1	the	the	DET
fnp-2819	74	2	difference	difference	NOUN
fnp-2819	74	3	in	in	ADP
fnp-2819	74	4	gene	gene	NOUN
fnp-2819	74	5	expression	expression	NOUN
fnp-2819	74	6	was	be	AUX
fnp-2819	74	7	calculated	calculate	VERB
fnp-2819	74	8	using	use	VERB
fnp-2819	74	9	an	an	DET
fnp-2819	74	10	unpaired	unpaired	ADJ
fnp-2819	74	11	two	two	NUM
fnp-2819	74	12	-	-	PUNCT
fnp-2819	74	13	tailed	tail	VERB
fnp-2819	74	14	student	student	NOUN
fnp-2819	74	15	's	's	PART
fnp-2819	74	16	t	t	NOUN
fnp-2819	74	17	-	-	PUNCT
fnp-2819	74	18	test	test	NOUN
fnp-2819	74	19	.	.	PUNCT
fnp-2819	75	1	elisa	elisa	PROPN
fnp-2819	75	2	data	datum	NOUN
fnp-2819	75	3	were	be	AUX
fnp-2819	75	4	analyzed	analyze	VERB
fnp-2819	75	5	for	for	ADP
fnp-2819	75	6	significance	significance	NOUN
fnp-2819	75	7	between	between	ADP
fnp-2819	75	8	groups	group	NOUN
fnp-2819	75	9	by	by	ADP
fnp-2819	75	10	two	two	NUM
fnp-2819	75	11	-	-	PUNCT
fnp-2819	75	12	way	way	NOUN
fnp-2819	75	13	anova	anova	PROPN
fnp-2819	75	14	.	.	PUNCT
fnp-2819	76	1	the	the	DET
fnp-2819	76	2	p	p	NOUN
fnp-2819	76	3	-	-	PUNCT
fnp-2819	76	4	value	value	NOUN
fnp-2819	76	5	of	of	ADP
fnp-2819	76	6	<	<	NOUN
fnp-2819	76	7	0.05	0.05	NUM
fnp-2819	76	8	was	be	AUX
fnp-2819	76	9	considered	consider	VERB
fnp-2819	76	10	significant	significant	ADJ
fnp-2819	76	11	.	.	PUNCT
fnp-2819	77	1	graphpad	graphpad	NOUN
fnp-2819	77	2	prism	prism	NOUN
fnp-2819	77	3	6.0	6.0	NUM
fnp-2819	77	4	software	software	NOUN
fnp-2819	77	5	(	(	PUNCT
fnp-2819	77	6	san	san	PROPN
fnp-2819	77	7	diego	diego	PROPN
fnp-2819	77	8	,	,	PUNCT
fnp-2819	77	9	ca	ca	PROPN
fnp-2819	77	10	)	)	PUNCT
fnp-2819	77	11	was	be	AUX
fnp-2819	77	12	used	use	VERB
fnp-2819	77	13	for	for	ADP
fnp-2819	77	14	all	all	DET
fnp-2819	77	15	statistical	statistical	ADJ
fnp-2819	77	16	analyses	analysis	NOUN
fnp-2819	77	17	.	.	PUNCT
fnp-2819	78	1	3	3	X
fnp-2819	78	2	.	.	NOUN
fnp-2819	78	3	results	result	VERB
fnp-2819	78	4	3.1	3.1	NUM
fnp-2819	78	5	.	.	PUNCT
fnp-2819	79	1	tsa	tsa	NOUN
fnp-2819	79	2	treatment	treatment	NOUN
fnp-2819	79	3	reduced	reduce	VERB
fnp-2819	79	4	the	the	DET
fnp-2819	79	5	clinical	clinical	ADJ
fnp-2819	79	6	manifestation	manifestation	NOUN
fnp-2819	79	7	of	of	ADP
fnp-2819	79	8	peae	peae	PROPN
fnp-2819	79	9	we	we	PRON
fnp-2819	79	10	have	have	AUX
fnp-2819	79	11	reported	report	VERB
fnp-2819	79	12	earlier	early	ADV
fnp-2819	79	13	that	that	SCONJ
fnp-2819	79	14	after	after	ADP
fnp-2819	79	15	immunization	immunization	NOUN
fnp-2819	79	16	with	with	ADP
fnp-2819	79	17	the	the	DET
fnp-2819	79	18	mog35	mog35	NOUN
fnp-2819	79	19	-	-	PUNCT
fnp-2819	79	20	55	55	NUM
fnp-2819	79	21	peptide	peptide	NOUN
fnp-2819	79	22	the	the	DET
fnp-2819	79	23	bodyweight	bodyweight	NOUN
fnp-2819	79	24	declined	decline	VERB
fnp-2819	79	25	transiently	transiently	ADV
fnp-2819	79	26	between	between	ADP
fnp-2819	79	27	13	13	NUM
fnp-2819	79	28	and	and	CCONJ
fnp-2819	79	29	16	16	NUM
fnp-2819	79	30	days	day	NOUN
fnp-2819	79	31	,	,	PUNCT
fnp-2819	79	32	which	which	PRON
fnp-2819	79	33	steadily	steadily	ADV
fnp-2819	79	34	increased	increase	VERB
fnp-2819	79	35	after	after	ADP
fnp-2819	79	36	that	that	PRON
fnp-2819	79	37	regardless	regardless	ADV
fnp-2819	79	38	of	of	ADP
fnp-2819	79	39	treatment	treatment	NOUN
fnp-2819	79	40	with	with	ADP
fnp-2819	79	41	dmso	dmso	NOUN
fnp-2819	79	42	or	or	CCONJ
fnp-2819	79	43	tsa	tsa	NOUN
fnp-2819	79	44	(	(	PUNCT
fnp-2819	79	45	jayaraman	jayaraman	NOUN
fnp-2819	79	46	et	et	PROPN
fnp-2819	79	47	al	al	PROPN
fnp-2819	79	48	.	.	PROPN
fnp-2819	79	49	,	,	PUNCT
fnp-2819	79	50	2017	2017	NUM
fnp-2819	79	51	)	)	PUNCT
fnp-2819	79	52	.	.	PUNCT
fnp-2819	80	1	since	since	SCONJ
fnp-2819	80	2	female	female	ADJ
fnp-2819	80	3	nod	nod	NOUN
fnp-2819	80	4	mice	mouse	NOUN
fnp-2819	80	5	develop	develop	VERB
fnp-2819	80	6	type	type	NOUN
fnp-2819	80	7	1	1	NUM
fnp-2819	80	8	diabetes	diabetes	NOUN
fnp-2819	80	9	in	in	ADP
fnp-2819	80	10	an	an	DET
fnp-2819	80	11	age	age	NOUN
fnp-2819	80	12	-	-	PUNCT
fnp-2819	80	13	dependent	dependent	ADJ
fnp-2819	80	14	manner	manner	NOUN
fnp-2819	80	15	,	,	PUNCT
fnp-2819	80	16	we	we	PRON
fnp-2819	80	17	routinely	routinely	ADV
fnp-2819	80	18	monitored	monitor	VERB
fnp-2819	80	19	blood	blood	NOUN
fnp-2819	80	20	glucose	glucose	NOUN
fnp-2819	80	21	levels	level	NOUN
fnp-2819	80	22	three	three	NUM
fnp-2819	80	23	times	time	NOUN
fnp-2819	80	24	a	a	DET
fnp-2819	80	25	week	week	NOUN
fnp-2819	80	26	throughout	throughout	ADP
fnp-2819	80	27	the	the	DET
fnp-2819	80	28	experiments	experiment	NOUN
fnp-2819	80	29	.	.	PUNCT
fnp-2819	81	1	as	as	SCONJ
fnp-2819	81	2	reported	report	VERB
fnp-2819	81	3	earlier	early	ADV
fnp-2819	81	4	(	(	PUNCT
fnp-2819	81	5	jayaraman	jayaraman	NOUN
fnp-2819	81	6	et	et	PROPN
fnp-2819	81	7	al	al	PROPN
fnp-2819	81	8	.	.	PROPN
fnp-2819	81	9	,	,	PUNCT
fnp-2819	81	10	2010	2010	NUM
fnp-2819	81	11	;	;	PUNCT
fnp-2819	81	12	2013	2013	NUM
fnp-2819	81	13	;	;	PUNCT
fnp-2819	81	14	jayaraman	jayaraman	NOUN
fnp-2819	81	15	and	and	CCONJ
fnp-2819	81	16	jayaraman	jayaraman	NOUN
fnp-2819	81	17	,	,	PUNCT
fnp-2819	81	18	2018	2018	NUM
fnp-2819	81	19	;	;	PUNCT
fnp-2819	81	20	patel	patel	PROPN
fnp-2819	81	21	et	et	PROPN
fnp-2819	81	22	al	al	PROPN
fnp-2819	81	23	.	.	PROPN
fnp-2819	81	24	,	,	PUNCT
fnp-2819	81	25	2011	2011	NUM
fnp-2819	81	26	)	)	PUNCT
fnp-2819	81	27	,	,	PUNCT
fnp-2819	81	28	mice	mouse	NOUN
fnp-2819	81	29	that	that	PRON
fnp-2819	81	30	were	be	AUX
fnp-2819	81	31	9	9	NUM
fnp-2819	81	32	-	-	SYM
fnp-2819	81	33	11	11	NUM
fnp-2819	81	34	weeks	week	NOUN
fnp-2819	81	35	old	old	ADJ
fnp-2819	81	36	(	(	PUNCT
fnp-2819	81	37	fig	fig	NOUN
fnp-2819	81	38	.	.	PUNCT
fnp-2819	82	1	1a	1a	X
fnp-2819	82	2	,	,	PUNCT
fnp-2819	82	3	d	d	X
fnp-2819	82	4	-	-	PUNCT
fnp-2819	82	5	e	e	NOUN
fnp-2819	82	6	)	)	PUNCT
fnp-2819	82	7	were	be	AUX
fnp-2819	82	8	normoglycemic	normoglycemic	ADJ
fnp-2819	82	9	at	at	ADP
fnp-2819	82	10	the	the	DET
fnp-2819	82	11	time	time	NOUN
fnp-2819	82	12	of	of	ADP
fnp-2819	82	13	immunization	immunization	NOUN
fnp-2819	82	14	with	with	ADP
fnp-2819	82	15	mog35	mog35	NOUN
fnp-2819	82	16	-	-	PUNCT
fnp-2819	82	17	55	55	NUM
fnp-2819	82	18	emulsified	emulsify	VERB
fnp-2819	82	19	in	in	ADP
fnp-2819	82	20	complete	complete	ADJ
fnp-2819	82	21	freund	freund	PROPN
fnp-2819	82	22	’s	’s	PART
fnp-2819	82	23	adjuvant	adjuvant	NOUN
fnp-2819	82	24	and	and	CCONJ
fnp-2819	82	25	remained	remain	VERB
fnp-2819	82	26	diabetes	diabetes	NOUN
fnp-2819	82	27	-	-	PUNCT
fnp-2819	82	28	free	free	ADJ
fnp-2819	82	29	throughout	throughout	ADP
fnp-2819	82	30	the	the	DET
fnp-2819	82	31	observation	observation	NOUN
fnp-2819	82	32	,	,	PUNCT
fnp-2819	82	33	12	12	NUM
fnp-2819	82	34	-	-	SYM
fnp-2819	82	35	27	27	NUM
fnp-2819	82	36	weeks	week	NOUN
fnp-2819	82	37	of	of	ADP
fnp-2819	82	38	age	age	NOUN
fnp-2819	82	39	(	(	PUNCT
fnp-2819	82	40	fig	fig	NOUN
fnp-2819	82	41	.	.	PUNCT
fnp-2819	83	1	1a	1a	X
fnp-2819	83	2	,	,	PUNCT
fnp-2819	83	3	d	d	X
fnp-2819	83	4	-	-	PUNCT
fnp-2819	83	5	e	e	NOUN
fnp-2819	83	6	)	)	PUNCT
fnp-2819	83	7	.	.	PUNCT
fnp-2819	84	1	however	however	ADV
fnp-2819	84	2	,	,	PUNCT
fnp-2819	84	3	in	in	ADP
fnp-2819	84	4	two	two	NUM
fnp-2819	84	5	experiments	experiment	NOUN
fnp-2819	84	6	,	,	PUNCT
fnp-2819	84	7	40	40	NUM
fnp-2819	84	8	and	and	CCONJ
fnp-2819	84	9	60	60	NUM
fnp-2819	84	10	%	%	NOUN
fnp-2819	84	11	of	of	ADP
fnp-2819	84	12	17	17	NUM
fnp-2819	84	13	-	-	PUNCT
fnp-2819	84	14	week	week	NOUN
fnp-2819	84	15	old	old	ADJ
fnp-2819	84	16	mice	mouse	NOUN
fnp-2819	84	17	immunized	immunize	VERB
fnp-2819	84	18	and	and	CCONJ
fnp-2819	84	19	treated	treat	VERB
fnp-2819	84	20	with	with	ADP
fnp-2819	84	21	dmso	dmso	NOUN
fnp-2819	84	22	were	be	AUX
fnp-2819	84	23	found	find	VERB
fnp-2819	84	24	to	to	PART
fnp-2819	84	25	be	be	AUX
fnp-2819	84	26	diabetic	diabetic	ADJ
fnp-2819	84	27	.	.	PUNCT
fnp-2819	85	1	tsa	tsa	NOUN
fnp-2819	85	2	treatment	treatment	NOUN
fnp-2819	85	3	reduced	reduce	VERB
fnp-2819	85	4	the	the	DET
fnp-2819	85	5	diabetes	diabetes	NOUN
fnp-2819	85	6	incidence	incidence	NOUN
fnp-2819	85	7	respectively	respectively	ADV
fnp-2819	85	8	to	to	ADP
fnp-2819	85	9	0	0	NUM
fnp-2819	85	10	%	%	NOUN
fnp-2819	85	11	and	and	CCONJ
fnp-2819	85	12	20	20	NUM
fnp-2819	85	13	%	%	NOUN
fnp-2819	85	14	when	when	SCONJ
fnp-2819	85	15	analyzed	analyze	VERB
fnp-2819	85	16	at	at	ADP
fnp-2819	85	17	20	20	NUM
fnp-2819	85	18	and	and	CCONJ
fnp-2819	85	19	21	21	NUM
fnp-2819	85	20	weeks	week	NOUN
fnp-2819	85	21	of	of	ADP
fnp-2819	85	22	age	age	NOUN
fnp-2819	85	23	(	(	PUNCT
fnp-2819	85	24	fig	fig	NOUN
fnp-2819	85	25	.	.	PUNCT
fnp-2819	86	1	1b	1b	NUM
fnp-2819	86	2	-	-	PUNCT
fnp-2819	86	3	c	c	NOUN
fnp-2819	86	4	)	)	PUNCT
fnp-2819	86	5	.	.	PUNCT
fnp-2819	87	1	these	these	DET
fnp-2819	87	2	results	result	NOUN
fnp-2819	87	3	are	be	AUX
fnp-2819	87	4	consistent	consistent	ADJ
fnp-2819	87	5	with	with	ADP
fnp-2819	87	6	our	our	PRON
fnp-2819	87	7	previous	previous	ADJ
fnp-2819	87	8	observations	observation	NOUN
fnp-2819	87	9	that	that	PRON
fnp-2819	87	10	the	the	DET
fnp-2819	87	11	administration	administration	NOUN
fnp-2819	87	12	of	of	ADP
fnp-2819	87	13	complete	complete	PROPN
fnp-2819	87	14	freund	freund	PROPN
fnp-2819	87	15	’s	’s	PART
fnp-2819	87	16	adjuvant	adjuvant	NOUN
fnp-2819	87	17	alone	alone	ADV
fnp-2819	87	18	could	could	AUX
fnp-2819	87	19	effectively	effectively	ADV
fnp-2819	87	20	prevent	prevent	VERB
fnp-2819	87	21	type	type	NOUN
fnp-2819	87	22	1	1	NUM
fnp-2819	87	23	diabetes	diabetes	NOUN
fnp-2819	87	24	in	in	ADP
fnp-2819	87	25	younger	young	ADJ
fnp-2819	87	26	female	female	ADJ
fnp-2819	87	27	nod	nod	NOUN
fnp-2819	87	28	mice	mouse	NOUN
fnp-2819	87	29	.	.	PUNCT
fnp-2819	88	1	in	in	ADP
fnp-2819	88	2	contrast	contrast	NOUN
fnp-2819	88	3	,	,	PUNCT
fnp-2819	88	4	similar	similar	ADJ
fnp-2819	88	5	treatment	treatment	NOUN
fnp-2819	88	6	of	of	ADP
fnp-2819	88	7	older	old	ADJ
fnp-2819	88	8	(	(	PUNCT
fnp-2819	88	9	>	>	SYM
fnp-2819	88	10	13	13	NUM
fnp-2819	88	11	-	-	PUNCT
fnp-2819	88	12	weeks	week	NOUN
fnp-2819	88	13	)	)	PUNCT
fnp-2819	88	14	mice	mouse	NOUN
fnp-2819	88	15	did	do	AUX
fnp-2819	88	16	not	not	PART
fnp-2819	88	17	have	have	VERB
fnp-2819	88	18	the	the	DET
fnp-2819	88	19	same	same	ADJ
fnp-2819	88	20	potency	potency	NOUN
fnp-2819	88	21	in	in	ADP
fnp-2819	88	22	preventing	prevent	VERB
fnp-2819	88	23	diabetes	diabetes	NOUN
fnp-2819	88	24	(	(	PUNCT
fnp-2819	88	25	jayaraman	jayaraman	NOUN
fnp-2819	88	26	and	and	CCONJ
fnp-2819	88	27	jayaraman	jayaraman	NOUN
fnp-2819	88	28	,	,	PUNCT
fnp-2819	88	29	2018	2018	NUM
fnp-2819	88	30	)	)	PUNCT
fnp-2819	88	31	.	.	PUNCT
fnp-2819	89	1	these	these	DET
fnp-2819	89	2	results	result	NOUN
fnp-2819	89	3	indicate	indicate	VERB
fnp-2819	89	4	that	that	SCONJ
fnp-2819	89	5	whereas	whereas	SCONJ
fnp-2819	89	6	the	the	DET
fnp-2819	89	7	development	development	NOUN
fnp-2819	89	8	of	of	ADP
fnp-2819	89	9	type	type	NOUN
fnp-2819	89	10	1	1	NUM
fnp-2819	89	11	diabetes	diabetes	NOUN
fnp-2819	89	12	is	be	AUX
fnp-2819	89	13	age	age	NOUN
fnp-2819	89	14	-	-	PUNCT
fnp-2819	89	15	dependent	dependent	ADJ
fnp-2819	89	16	,	,	PUNCT
fnp-2819	89	17	induction	induction	NOUN
fnp-2819	89	18	of	of	ADP
fnp-2819	89	19	peae	peae	PROPN
fnp-2819	89	20	by	by	ADP
fnp-2819	89	21	immunization	immunization	NOUN
fnp-2819	89	22	with	with	ADP
fnp-2819	89	23	the	the	DET
fnp-2819	89	24	mog35	mog35	NOUN
fnp-2819	89	25	-	-	PUNCT
fnp-2819	89	26	55	55	NUM
fnp-2819	89	27	peptide	peptide	NOUN
fnp-2819	89	28	emulsified	emulsify	VERB
fnp-2819	89	29	in	in	ADP
fnp-2819	89	30	complete	complete	ADJ
fnp-2819	89	31	freund	freund	PROPN
fnp-2819	89	32	’s	’s	PART
fnp-2819	89	33	adjuvant	adjuvant	NOUN
fnp-2819	89	34	is	be	AUX
fnp-2819	89	35	independent	independent	ADJ
fnp-2819	89	36	of	of	ADP
fnp-2819	89	37	the	the	DET
fnp-2819	89	38	age	age	NOUN
fnp-2819	89	39	and	and	CCONJ
fnp-2819	89	40	the	the	DET
fnp-2819	89	41	glycemic	glycemic	ADJ
fnp-2819	89	42	status	status	NOUN
fnp-2819	89	43	of	of	ADP
fnp-2819	89	44	mice	mouse	NOUN
fnp-2819	89	45	.	.	PUNCT
fnp-2819	90	1	fig	fig	NOUN
fnp-2819	90	2	.	.	PUNCT
fnp-2819	91	1	1	1	NUM
fnp-2819	91	2	tsa	tsa	NOUN
fnp-2819	91	3	treatment	treatment	NOUN
fnp-2819	91	4	improved	improve	VERB
fnp-2819	91	5	clinical	clinical	ADJ
fnp-2819	91	6	disease	disease	NOUN
fnp-2819	91	7	.	.	PUNCT
fnp-2819	91	8	  	  	SPACE
fnp-2819	91	9	randomly	randomly	ADV
fnp-2819	91	10	chosen	choose	VERB
fnp-2819	91	11	littermates	littermate	NOUN
fnp-2819	91	12	of	of	ADP
fnp-2819	91	13	female	female	ADJ
fnp-2819	91	14	nod	nod	NOUN
fnp-2819	91	15	mice	mouse	NOUN
fnp-2819	91	16	were	be	AUX
fnp-2819	91	17	immunized	immunize	VERB
fnp-2819	91	18	with	with	ADP
fnp-2819	91	19	mog35	mog35	NOUN
fnp-2819	91	20	-	-	PUNCT
fnp-2819	91	21	55	55	NUM
fnp-2819	91	22	and	and	CCONJ
fnp-2819	91	23	treated	treat	VERB
fnp-2819	91	24	with	with	ADP
fnp-2819	91	25	tsa	tsa	NOUN
fnp-2819	91	26	or	or	CCONJ
fnp-2819	91	27	dmso	dmso	NOUN
fnp-2819	91	28	three	three	NUM
fnp-2819	91	29	times	time	NOUN
fnp-2819	91	30	a	a	DET
fnp-2819	91	31	week	week	NOUN
fnp-2819	91	32	for	for	ADP
fnp-2819	91	33	the	the	DET
fnp-2819	91	34	indicated	indicate	VERB
fnp-2819	91	35	time	time	NOUN
fnp-2819	91	36	interval	interval	NOUN
fnp-2819	91	37	.	.	PUNCT
fnp-2819	92	1	clinical	clinical	ADJ
fnp-2819	92	2	scores	score	NOUN
fnp-2819	92	3	of	of	ADP
fnp-2819	92	4	five	five	NUM
fnp-2819	92	5	mice	mouse	NOUN
fnp-2819	92	6	/	/	SYM
fnp-2819	92	7	group	group	NOUN
fnp-2819	92	8	were	be	AUX
fnp-2819	92	9	determined	determine	VERB
fnp-2819	92	10	on	on	ADP
fnp-2819	92	11	indicated	indicate	VERB
fnp-2819	92	12	time	time	NOUN
fnp-2819	92	13	intervals	interval	NOUN
fnp-2819	92	14	and	and	CCONJ
fnp-2819	92	15	depicted	depict	VERB
fnp-2819	92	16	as	as	ADP
fnp-2819	92	17	mean	mean	PROPN
fnp-2819	92	18	±	±	NUM
fnp-2819	92	19	sem	sem	NOUN
fnp-2819	92	20	.	.	PUNCT
fnp-2819	93	1	the	the	DET
fnp-2819	93	2	statistical	statistical	ADJ
fnp-2819	93	3	significance	significance	NOUN
fnp-2819	93	4	between	between	ADP
fnp-2819	93	5	dmso	dmso	NOUN
fnp-2819	93	6	(	(	PUNCT
fnp-2819	93	7	blank	blank	ADJ
fnp-2819	93	8	bars	bar	NOUN
fnp-2819	93	9	)	)	PUNCT
fnp-2819	93	10	and	and	CCONJ
fnp-2819	93	11	tsa	tsa	NOUN
fnp-2819	93	12	-	-	PUNCT
fnp-2819	93	13	treated	treat	VERB
fnp-2819	93	14	mice	mouse	NOUN
fnp-2819	93	15	(	(	PUNCT
fnp-2819	93	16	hatched	hatch	VERB
fnp-2819	93	17	bars	bar	NOUN
fnp-2819	93	18	)	)	PUNCT
fnp-2819	93	19	was	be	AUX
fnp-2819	93	20	determined	determine	VERB
fnp-2819	93	21	using	use	VERB
fnp-2819	93	22	the	the	DET
fnp-2819	93	23	area	area	NOUN
fnp-2819	93	24	under	under	ADP
fnp-2819	93	25	the	the	DET
fnp-2819	93	26	roc	roc	PROPN
fnp-2819	93	27	curve	curve	NOUN
fnp-2819	93	28	test	test	NOUN
fnp-2819	93	29	and	and	CCONJ
fnp-2819	93	30	indicated	indicate	VERB
fnp-2819	93	31	.	.	PUNCT
fnp-2819	94	1	individual	individual	ADJ
fnp-2819	94	2	data	datum	NOUN
fnp-2819	94	3	for	for	ADP
fnp-2819	94	4	dmso	dmso	NOUN
fnp-2819	94	5	(	(	PUNCT
fnp-2819	94	6	empty	empty	ADJ
fnp-2819	94	7	circles	circle	NOUN
fnp-2819	94	8	)	)	PUNCT
fnp-2819	94	9	and	and	CCONJ
fnp-2819	94	10	tsa	tsa	NOUN
fnp-2819	94	11	-	-	PUNCT
fnp-2819	94	12	treated	treat	VERB
fnp-2819	94	13	(	(	PUNCT
fnp-2819	94	14	empty	empty	ADJ
fnp-2819	94	15	squares	square	NOUN
fnp-2819	94	16	)	)	PUNCT
fnp-2819	94	17	groups	group	NOUN
fnp-2819	94	18	are	be	AUX
fnp-2819	94	19	also	also	ADV
fnp-2819	94	20	indicated	indicate	VERB
fnp-2819	94	21	.	.	PUNCT
fnp-2819	95	1	mice	mouse	NOUN
fnp-2819	95	2	were	be	AUX
fnp-2819	95	3	killed	kill	VERB
fnp-2819	95	4	on	on	ADP
fnp-2819	95	5	day	day	NOUN
fnp-2819	95	6	14	14	NUM
fnp-2819	95	7	(	(	PUNCT
fnp-2819	95	8	a	a	NOUN
fnp-2819	95	9	)	)	PUNCT
fnp-2819	95	10	,	,	PUNCT
fnp-2819	95	11	21	21	NUM
fnp-2819	95	12	(	(	PUNCT
fnp-2819	95	13	b	b	NOUN
fnp-2819	95	14	)	)	PUNCT
fnp-2819	95	15	,	,	PUNCT
fnp-2819	95	16	28	28	NUM
fnp-2819	95	17	(	(	PUNCT
fnp-2819	95	18	c	c	NOUN
fnp-2819	95	19	)	)	PUNCT
fnp-2819	95	20	,	,	PUNCT
fnp-2819	95	21	54	54	NUM
fnp-2819	95	22	(	(	PUNCT
fnp-2819	95	23	d	d	NOUN
fnp-2819	95	24	)	)	PUNCT
fnp-2819	95	25	,	,	PUNCT
fnp-2819	95	26	and	and	CCONJ
fnp-2819	95	27	115	115	NUM
fnp-2819	95	28	(	(	PUNCT
fnp-2819	95	29	e	e	NOUN
fnp-2819	95	30	)	)	PUNCT
fnp-2819	95	31	,	,	PUNCT
fnp-2819	95	32	and	and	CCONJ
fnp-2819	95	33	their	their	PRON
fnp-2819	95	34	spinal	spinal	ADJ
fnp-2819	95	35	cord	cord	NOUN
fnp-2819	95	36	and	and	CCONJ
fnp-2819	95	37	peripheral	peripheral	ADJ
fnp-2819	95	38	lymphoid	lymphoid	ADJ
fnp-2819	95	39	tissues	tissue	NOUN
fnp-2819	95	40	were	be	AUX
fnp-2819	95	41	harvested	harvest	VERB
fnp-2819	95	42	and	and	CCONJ
fnp-2819	95	43	used	use	VERB
fnp-2819	95	44	for	for	ADP
fnp-2819	95	45	gene	gene	NOUN
fnp-2819	95	46	expression	expression	NOUN
fnp-2819	95	47	analysis	analysis	NOUN
fnp-2819	95	48	.	.	PUNCT
fnp-2819	96	1	all	all	PRON
fnp-2819	96	2	of	of	ADP
fnp-2819	96	3	the	the	DET
fnp-2819	96	4	mice	mouse	NOUN
fnp-2819	96	5	immunized	immunize	VERB
fnp-2819	96	6	with	with	ADP
fnp-2819	96	7	mog35	mog35	NOUN
fnp-2819	96	8	-	-	PUNCT
fnp-2819	96	9	55	55	NUM
fnp-2819	96	10	developed	develop	VERB
fnp-2819	96	11	peae	peae	NOUN
fnp-2819	96	12	without	without	ADP
fnp-2819	96	13	discernible	discernible	ADJ
fnp-2819	96	14	remission	remission	NOUN
fnp-2819	96	15	(	(	PUNCT
fnp-2819	96	16	fig	fig	NOUN
fnp-2819	96	17	.	.	PUNCT
fnp-2819	97	1	1a	1a	X
fnp-2819	97	2	-	-	PUNCT
fnp-2819	97	3	e	e	NOUN
fnp-2819	97	4	)	)	PUNCT
fnp-2819	97	5	,	,	PUNCT
fnp-2819	97	6	consistent	consistent	ADJ
fnp-2819	97	7	with	with	ADP
fnp-2819	97	8	earlier	early	ADJ
fnp-2819	97	9	reports	report	NOUN
fnp-2819	97	10	(	(	PUNCT
fnp-2819	97	11	basso	basso	NOUN
fnp-2819	97	12	et	et	PROPN
fnp-2819	97	13	al	al	PROPN
fnp-2819	97	14	.	.	PROPN
fnp-2819	97	15	,	,	PUNCT
fnp-2819	97	16	2008	2008	NUM
fnp-2819	97	17	;	;	PUNCT
fnp-2819	97	18	jayaraman	jayaraman	NOUN
fnp-2819	97	19	et	et	PROPN
fnp-2819	97	20	al	al	PROPN
fnp-2819	97	21	.	.	PROPN
fnp-2819	97	22	,	,	PUNCT
fnp-2819	97	23	2017	2017	NUM
fnp-2819	97	24	;	;	PUNCT
fnp-2819	97	25	2018	2018	NUM
fnp-2819	97	26	)	)	PUNCT
fnp-2819	97	27	.	.	PUNCT
fnp-2819	98	1	the	the	DET
fnp-2819	98	2	overall	overall	ADJ
fnp-2819	98	3	clinical	clinical	ADJ
fnp-2819	98	4	severity	severity	NOUN
fnp-2819	98	5	was	be	AUX
fnp-2819	98	6	comparable	comparable	ADJ
fnp-2819	98	7	in	in	ADP
fnp-2819	98	8	most	most	ADJ
fnp-2819	98	9	instances	instance	NOUN
fnp-2819	98	10	except	except	SCONJ
fnp-2819	98	11	in	in	ADP
fnp-2819	98	12	a	a	DET
fnp-2819	98	13	single	single	ADJ
fnp-2819	98	14	experiment	experiment	NOUN
fnp-2819	98	15	,	,	PUNCT
fnp-2819	98	16	probably	probably	ADV
fnp-2819	98	17	due	due	ADP
fnp-2819	98	18	to	to	ADP
fnp-2819	98	19	the	the	DET
fnp-2819	98	20	difference	difference	NOUN
fnp-2819	98	21	in	in	ADP
fnp-2819	98	22	experimental	experimental	ADJ
fnp-2819	98	23	conditions	condition	NOUN
fnp-2819	98	24	(	(	PUNCT
fnp-2819	98	25	fig	fig	NOUN
fnp-2819	98	26	.	.	PUNCT
fnp-2819	99	1	1c	1c	NOUN
fnp-2819	99	2	)	)	PUNCT
fnp-2819	99	3	.	.	PUNCT
fnp-2819	100	1	treatment	treatment	NOUN
fnp-2819	100	2	with	with	ADP
fnp-2819	100	3	tsa	tsa	NOUN
fnp-2819	100	4	bestowed	bestow	VERB
fnp-2819	100	5	robust	robust	ADJ
fnp-2819	100	6	and	and	CCONJ
fnp-2819	100	7	irreversible	irreversible	ADJ
fnp-2819	100	8	protection	protection	NOUN
fnp-2819	100	9	from	from	ADP
fnp-2819	100	10	peae	peae	PROPN
fnp-2819	100	11	for	for	ADP
fnp-2819	100	12	the	the	DET
fnp-2819	100	13	entire	entire	ADJ
fnp-2819	100	14	period	period	NOUN
fnp-2819	100	15	of	of	ADP
fnp-2819	100	16	observation	observation	NOUN
fnp-2819	100	17	(	(	PUNCT
fnp-2819	100	18	115	115	NUM
fnp-2819	100	19	days	day	NOUN
fnp-2819	100	20	)	)	PUNCT
fnp-2819	100	21	even	even	ADV
fnp-2819	100	22	after	after	ADP
fnp-2819	100	23	the	the	DET
fnp-2819	100	24	cessation	cessation	NOUN
fnp-2819	100	25	of	of	ADP
fnp-2819	100	26	the	the	DET
fnp-2819	100	27	drug	drug	NOUN
fnp-2819	100	28	administration	administration	NOUN
fnp-2819	100	29	on	on	ADP
fnp-2819	100	30	day	day	NOUN
fnp-2819	100	31	45	45	NUM
fnp-2819	100	32	(	(	PUNCT
fnp-2819	100	33	fig	fig	NOUN
fnp-2819	100	34	.	.	PUNCT
fnp-2819	101	1	1e	1e	NUM
fnp-2819	101	2	)	)	PUNCT
fnp-2819	101	3	,	,	PUNCT
fnp-2819	101	4	as	as	SCONJ
fnp-2819	101	5	reported	report	VERB
fnp-2819	101	6	earlier	early	ADV
fnp-2819	101	7	(	(	PUNCT
fnp-2819	101	8	jayaraman	jayaraman	NOUN
fnp-2819	101	9	et	et	PROPN
fnp-2819	101	10	al	al	PROPN
fnp-2819	101	11	.	.	PROPN
fnp-2819	101	12	,	,	PUNCT
fnp-2819	101	13	2017	2017	NUM
fnp-2819	101	14	)	)	PUNCT
fnp-2819	101	15	.	.	PUNCT
fnp-2819	102	1	interestingly	interestingly	ADV
fnp-2819	102	2	,	,	PUNCT
fnp-2819	102	3	the	the	DET
fnp-2819	102	4	administration	administration	NOUN
fnp-2819	102	5	of	of	ADP
fnp-2819	102	6	the	the	DET
fnp-2819	102	7	drug	drug	NOUN
fnp-2819	102	8	for	for	ADP
fnp-2819	102	9	one	one	NUM
fnp-2819	102	10	(	(	PUNCT
fnp-2819	102	11	fig	fig	NOUN
fnp-2819	102	12	.	.	PUNCT
fnp-2819	103	1	1a	1a	NOUN
fnp-2819	103	2	)	)	PUNCT
fnp-2819	103	3	,	,	PUNCT
fnp-2819	103	4	two	two	NUM
fnp-2819	103	5	(	(	PUNCT
fnp-2819	103	6	fig	fig	NOUN
fnp-2819	103	7	.	.	PUNCT
fnp-2819	104	1	1b	1b	NUM
fnp-2819	104	2	,	,	PUNCT
fnp-2819	104	3	c	c	NOUN
fnp-2819	104	4	)	)	PUNCT
fnp-2819	104	5	,	,	PUNCT
fnp-2819	104	6	four	four	NUM
fnp-2819	104	7	(	(	PUNCT
fnp-2819	104	8	fig	fig	NOUN
fnp-2819	104	9	.	.	PUNCT
fnp-2819	105	1	1d	1d	NUM
fnp-2819	105	2	)	)	PUNCT
fnp-2819	105	3	or	or	CCONJ
fnp-2819	105	4	six	six	NUM
fnp-2819	105	5	-	-	PUNCT
fnp-2819	105	6	weeks	week	NOUN
fnp-2819	105	7	(	(	PUNCT
fnp-2819	105	8	fig	fig	NOUN
fnp-2819	105	9	.	.	PUNCT
fnp-2819	106	1	1e	1e	NOUN
fnp-2819	106	2	)	)	PUNCT
fnp-2819	106	3	afforded	afford	VERB
fnp-2819	106	4	a	a	DET
fnp-2819	106	5	comparable	comparable	ADJ
fnp-2819	106	6	level	level	NOUN
fnp-2819	106	7	of	of	ADP
fnp-2819	106	8	protection	protection	NOUN
fnp-2819	106	9	against	against	ADP
fnp-2819	106	10	the	the	DET
fnp-2819	106	11	disease	disease	NOUN
fnp-2819	106	12	.	.	PUNCT
fnp-2819	107	1	in	in	ADP
fnp-2819	107	2	previous	previous	ADJ
fnp-2819	107	3	studies	study	NOUN
fnp-2819	107	4	,	,	PUNCT
fnp-2819	107	5	we	we	PRON
fnp-2819	107	6	have	have	AUX
fnp-2819	107	7	demonstrated	demonstrate	VERB
fnp-2819	107	8	that	that	SCONJ
fnp-2819	107	9	chronic	chronic	ADJ
fnp-2819	107	10	tsa	tsa	NOUN
fnp-2819	107	11	treatment	treatment	NOUN
fnp-2819	107	12	decreased	decrease	VERB
fnp-2819	107	13	the	the	DET
fnp-2819	107	14	influx	influx	NOUN
fnp-2819	107	15	of	of	ADP
fnp-2819	107	16	neutrophils	neutrophil	NOUN
fnp-2819	107	17	and	and	CCONJ
fnp-2819	107	18	cd4	cd4	PROPN
fnp-2819	107	19	+	+	PROPN
fnp-2819	107	20	t	t	NOUN
fnp-2819	107	21	cells	cell	NOUN
fnp-2819	107	22	into	into	ADP
fnp-2819	107	23	the	the	DET
fnp-2819	107	24	sc	sc	PROPN
fnp-2819	107	25	.	.	PUNCT
fnp-2819	107	26	drug	drug	PROPN
fnp-2819	107	27	treatment	treatment	NOUN
fnp-2819	107	28	also	also	ADV
fnp-2819	107	29	reduced	reduce	VERB
fnp-2819	107	30	the	the	DET
fnp-2819	107	31	inflammation	inflammation	NOUN
fnp-2819	107	32	and	and	CCONJ
fnp-2819	107	33	particularly	particularly	ADV
fnp-2819	107	34	axonal	axonal	ADJ
fnp-2819	107	35	damage	damage	NOUN
fnp-2819	107	36	in	in	ADP
fnp-2819	107	37	the	the	DET
fnp-2819	107	38	spinal	spinal	NOUN
fnp-2819	107	39	cord	cord	NOUN
fnp-2819	107	40	,	,	PUNCT
fnp-2819	107	41	indicating	indicate	VERB
fnp-2819	107	42	the	the	DET
fnp-2819	107	43	neuroprotective	neuroprotective	ADJ
fnp-2819	107	44	effect	effect	NOUN
fnp-2819	107	45	of	of	ADP
fnp-2819	107	46	the	the	DET
fnp-2819	107	47	hdac	hdac	NOUN
fnp-2819	107	48	inhibitor	inhibitor	NOUN
fnp-2819	107	49	(	(	PUNCT
fnp-2819	107	50	jayaraman	jayaraman	PROPN
fnp-2819	107	51	et	et	PROPN
fnp-2819	107	52	al	al	PROPN
fnp-2819	107	53	.	.	PROPN
fnp-2819	107	54	,	,	PUNCT
fnp-2819	107	55	2017	2017	NUM
fnp-2819	107	56	;	;	PUNCT
fnp-2819	107	57	2018	2018	NUM
fnp-2819	107	58	)	)	PUNCT
fnp-2819	107	59	.	.	PUNCT
fnp-2819	108	1	to	to	PART
fnp-2819	108	2	understand	understand	VERB
fnp-2819	108	3	the	the	DET
fnp-2819	108	4	underlying	underlying	ADJ
fnp-2819	108	5	mechanisms	mechanism	NOUN
fnp-2819	108	6	of	of	ADP
fnp-2819	108	7	drug	drug	NOUN
fnp-2819	108	8	-	-	PUNCT
fnp-2819	108	9	mediated	mediate	VERB
fnp-2819	108	10	protection	protection	NOUN
fnp-2819	108	11	against	against	ADP
fnp-2819	108	12	peae	peae	PROPN
fnp-2819	108	13	,	,	PUNCT
fnp-2819	108	14	in	in	ADP
fnp-2819	108	15	the	the	DET
fnp-2819	108	16	current	current	ADJ
fnp-2819	108	17	study	study	NOUN
fnp-2819	108	18	,	,	PUNCT
fnp-2819	108	19	we	we	PRON
fnp-2819	108	20	have	have	AUX
fnp-2819	108	21	concurrently	concurrently	ADV
fnp-2819	108	22	profiled	profile	VERB
fnp-2819	108	23	the	the	DET
fnp-2819	108	24	gene	gene	NOUN
fnp-2819	108	25	expression	expression	NOUN
fnp-2819	108	26	in	in	ADP
fnp-2819	108	27	the	the	DET
fnp-2819	108	28	cns	cns	NOUN
fnp-2819	108	29	and	and	CCONJ
fnp-2819	108	30	slo	slo	PROPN
fnp-2819	108	31	at	at	ADP
fnp-2819	108	32	various	various	ADJ
fnp-2819	108	33	time	time	NOUN
fnp-2819	108	34	points	point	NOUN
fnp-2819	108	35	shown	show	VERB
fnp-2819	108	36	in	in	ADP
fnp-2819	108	37	fig	fig	NOUN
fnp-2819	108	38	.	.	PUNCT
fnp-2819	109	1	1a	1a	PROPN
fnp-2819	109	2	-	-	PUNCT
fnp-2819	109	3	e.	e.	PROPN
fnp-2819	109	4	3.2	3.2	NUM
fnp-2819	109	5	.	.	PUNCT
fnp-2819	110	1	differential	differential	ADJ
fnp-2819	110	2	impact	impact	NOUN
fnp-2819	110	3	of	of	ADP
fnp-2819	110	4	the	the	DET
fnp-2819	110	5	histone	histone	NOUN
fnp-2819	110	6	modifier	modifier	NOUN
fnp-2819	110	7	on	on	ADP
fnp-2819	110	8	gene	gene	NOUN
fnp-2819	110	9	expression	expression	NOUN
fnp-2819	110	10	in	in	ADP
fnp-2819	110	11	the	the	DET
fnp-2819	110	12	cns	cns	NOUN
fnp-2819	110	13	the	the	DET
fnp-2819	110	14	neuronal	neuronal	ADJ
fnp-2819	110	15	disease	disease	NOUN
fnp-2819	110	16	induced	induce	VERB
fnp-2819	110	17	in	in	ADP
fnp-2819	110	18	nod	nod	NOUN
fnp-2819	110	19	mice	mouse	NOUN
fnp-2819	110	20	resembled	resemble	VERB
fnp-2819	110	21	the	the	DET
fnp-2819	110	22	‘	'	PUNCT
fnp-2819	110	23	classic	classic	ADJ
fnp-2819	110	24	’	'	PUNCT
fnp-2819	110	25	eae	eae	NOUN
fnp-2819	110	26	except	except	SCONJ
fnp-2819	110	27	that	that	SCONJ
fnp-2819	110	28	it	it	PRON
fnp-2819	110	29	lasted	last	VERB
fnp-2819	110	30	longer	long	ADV
fnp-2819	110	31	than	than	ADP
fnp-2819	110	32	in	in	ADP
fnp-2819	110	33	most	most	ADJ
fnp-2819	110	34	strains	strain	NOUN
fnp-2819	110	35	of	of	ADP
fnp-2819	110	36	mice	mouse	NOUN
fnp-2819	110	37	(	(	PUNCT
fnp-2819	110	38	slavin	slavin	NOUN
fnp-2819	110	39	et	et	PROPN
fnp-2819	110	40	al	al	PROPN
fnp-2819	110	41	.	.	PROPN
fnp-2819	110	42	,	,	PUNCT
fnp-2819	110	43	1998	1998	NUM
fnp-2819	110	44	;	;	PUNCT
fnp-2819	110	45	basso	basso	PROPN
fnp-2819	110	46	et	et	PROPN
fnp-2819	110	47	al	al	PROPN
fnp-2819	110	48	.	.	PROPN
fnp-2819	110	49	,	,	PUNCT
fnp-2819	110	50	2008	2008	NUM
fnp-2819	110	51	;	;	PUNCT
fnp-2819	110	52	hidaka	hidaka	PROPN
fnp-2819	110	53	et	et	PROPN
fnp-2819	110	54	al	al	PROPN
fnp-2819	110	55	.	.	PROPN
fnp-2819	110	56	,	,	PUNCT
fnp-2819	110	57	2014	2014	NUM
fnp-2819	110	58	;	;	PUNCT
fnp-2819	110	59	dang	dang	INTJ
fnp-2819	110	60	et	et	PROPN
fnp-2819	110	61	al	al	PROPN
fnp-2819	110	62	.	.	PROPN
fnp-2819	110	63	,	,	PUNCT
fnp-2819	110	64	2015	2015	NUM
fnp-2819	110	65	;	;	PUNCT
fnp-2819	110	66	jayaraman	jayaraman	NOUN
fnp-2819	110	67	et	et	PROPN
fnp-2819	110	68	al	al	PROPN
fnp-2819	110	69	.	.	PROPN
fnp-2819	110	70	,	,	PUNCT
fnp-2819	110	71	2017	2017	NUM
fnp-2819	110	72	;	;	PUNCT
fnp-2819	110	73	2018	2018	NUM
fnp-2819	110	74	)	)	PUNCT
fnp-2819	110	75	.	.	PUNCT
fnp-2819	111	1	since	since	SCONJ
fnp-2819	111	2	the	the	DET
fnp-2819	111	3	sc	sc	PROPN
fnp-2819	111	4	is	be	AUX
fnp-2819	111	5	thought	think	VERB
fnp-2819	111	6	to	to	PART
fnp-2819	111	7	be	be	AUX
fnp-2819	111	8	the	the	DET
fnp-2819	111	9	primary	primary	ADJ
fnp-2819	111	10	target	target	NOUN
fnp-2819	111	11	of	of	ADP
fnp-2819	111	12	the	the	DET
fnp-2819	111	13	‘	'	PUNCT
fnp-2819	111	14	classic	classic	ADJ
fnp-2819	111	15	’	'	PUNCT
fnp-2819	111	16	eae	eae	PROPN
fnp-2819	111	17	and	and	CCONJ
fnp-2819	111	18	the	the	DET
fnp-2819	111	19	brain	brain	NOUN
fnp-2819	111	20	damage	damage	NOUN
fnp-2819	111	21	was	be	AUX
fnp-2819	111	22	selectively	selectively	ADV
fnp-2819	111	23	observed	observe	VERB
fnp-2819	111	24	in	in	ADP
fnp-2819	111	25	'	'	PUNCT
fnp-2819	111	26	atypical	atypical	ADJ
fnp-2819	111	27	’	'	PUNCT
fnp-2819	111	28	eae	eae	PROPN
fnp-2819	111	29	(	(	PUNCT
fnp-2819	111	30	pierson	pierson	PROPN
fnp-2819	111	31	and	and	CCONJ
fnp-2819	111	32	goverman	goverman	NOUN
fnp-2819	111	33	,	,	PUNCT
fnp-2819	111	34	2017	2017	NUM
fnp-2819	111	35	)	)	PUNCT
fnp-2819	111	36	,	,	PUNCT
fnp-2819	111	37	we	we	PRON
fnp-2819	111	38	profiled	profile	VERB
fnp-2819	111	39	the	the	DET
fnp-2819	111	40	gene	gene	NOUN
fnp-2819	111	41	expression	expression	NOUN
fnp-2819	111	42	in	in	ADP
fnp-2819	111	43	the	the	DET
fnp-2819	111	44	entire	entire	ADJ
fnp-2819	111	45	sc	sc	PROPN
fnp-2819	111	46	.	.	PUNCT
fnp-2819	112	1	expression	expression	NOUN
fnp-2819	112	2	levels	level	NOUN
fnp-2819	112	3	of	of	ADP
fnp-2819	112	4	genes	gene	NOUN
fnp-2819	112	5	encoding	encode	VERB
fnp-2819	112	6	11	11	NUM
fnp-2819	112	7	lymphokines	lymphokine	NOUN
fnp-2819	112	8	,	,	PUNCT
fnp-2819	112	9	four	four	NUM
fnp-2819	112	10	cytokines	cytokine	NOUN
fnp-2819	112	11	,	,	PUNCT
fnp-2819	112	12	seven	seven	NUM
fnp-2819	112	13	accessory	accessory	NOUN
fnp-2819	112	14	cell	cell	NOUN
fnp-2819	112	15	surface	surface	NOUN
fnp-2819	112	16	-	-	PUNCT
fnp-2819	112	17	associated	associate	VERB
fnp-2819	112	18	determinants	determinant	NOUN
fnp-2819	112	19	,	,	PUNCT
fnp-2819	112	20	seven	seven	NUM
fnp-2819	112	21	transcription	transcription	NOUN
fnp-2819	112	22	factors	factor	NOUN
fnp-2819	112	23	,	,	PUNCT
fnp-2819	112	24	and	and	CCONJ
fnp-2819	112	25	11	11	NUM
fnp-2819	112	26	histone	histone	NOUN
fnp-2819	112	27	deacetylases	deacetylase	NOUN
fnp-2819	112	28	(	(	PUNCT
fnp-2819	112	29	hdacs	hdac	NOUN
fnp-2819	112	30	)	)	PUNCT
fnp-2819	112	31	were	be	AUX
fnp-2819	112	32	investigated	investigate	VERB
fnp-2819	112	33	by	by	ADP
fnp-2819	112	34	qrt	qrt	NOUN
fnp-2819	112	35	-	-	PUNCT
fnp-2819	112	36	pcr	pcr	ADJ
fnp-2819	112	37	.	.	PUNCT
fnp-2819	113	1	unimmunized	unimmunized	ADJ
fnp-2819	113	2	mice	mouse	NOUN
fnp-2819	113	3	were	be	AUX
fnp-2819	113	4	separately	separately	ADV
fnp-2819	113	5	treated	treat	VERB
fnp-2819	113	6	with	with	ADP
fnp-2819	113	7	dmso	dmso	NOUN
fnp-2819	113	8	or	or	CCONJ
fnp-2819	113	9	tsa	tsa	NOUN
fnp-2819	113	10	to	to	PART
fnp-2819	113	11	determine	determine	VERB
fnp-2819	113	12	the	the	DET
fnp-2819	113	13	impact	impact	NOUN
fnp-2819	113	14	of	of	ADP
fnp-2819	113	15	drug	drug	NOUN
fnp-2819	113	16	treatment	treatment	NOUN
fnp-2819	113	17	on	on	ADP
fnp-2819	113	18	the	the	DET
fnp-2819	113	19	constitutive	constitutive	ADJ
fnp-2819	113	20	level	level	NOUN
fnp-2819	113	21	of	of	ADP
fnp-2819	113	22	gene	gene	NOUN
fnp-2819	113	23	expression	expression	NOUN
fnp-2819	113	24	.	.	PUNCT
fnp-2819	114	1	the	the	DET
fnp-2819	114	2	data	datum	NOUN
fnp-2819	114	3	are	be	AUX
fnp-2819	114	4	indicated	indicate	VERB
fnp-2819	114	5	at	at	ADP
fnp-2819	114	6	the	the	DET
fnp-2819	114	7	day-1	day-1	NUM
fnp-2819	114	8	time	time	NOUN
fnp-2819	114	9	point	point	NOUN
fnp-2819	114	10	in	in	ADP
fnp-2819	114	11	all	all	DET
fnp-2819	114	12	figures	figure	NOUN
fnp-2819	114	13	.	.	PUNCT
fnp-2819	115	1	mice	mouse	NOUN
fnp-2819	115	2	immunized	immunize	VERB
fnp-2819	115	3	with	with	ADP
fnp-2819	115	4	mog35	mog35	NOUN
fnp-2819	115	5	-	-	PUNCT
fnp-2819	115	6	55	55	NUM
fnp-2819	115	7	were	be	AUX
fnp-2819	115	8	treated	treat	VERB
fnp-2819	115	9	with	with	ADP
fnp-2819	115	10	dmso	dmso	NOUN
fnp-2819	115	11	or	or	CCONJ
fnp-2819	115	12	tsa	tsa	NOUN
fnp-2819	115	13	starting	start	VERB
fnp-2819	115	14	from	from	ADP
fnp-2819	115	15	the	the	DET
fnp-2819	115	16	day	day	NOUN
fnp-2819	115	17	of	of	ADP
fnp-2819	115	18	immunization	immunization	NOUN
fnp-2819	115	19	.	.	PUNCT
fnp-2819	116	1	the	the	DET
fnp-2819	116	2	entire	entire	ADJ
fnp-2819	116	3	data	data	NOUN
fnp-2819	116	4	sets	set	NOUN
fnp-2819	116	5	are	be	AUX
fnp-2819	116	6	presented	present	VERB
fnp-2819	116	7	in	in	ADP
fnp-2819	116	8	supplementary	supplementary	ADJ
fnp-2819	116	9	fig	fig	NOUN
fnp-2819	116	10	.	.	PUNCT
fnp-2819	117	1	1	1	NUM
fnp-2819	117	2	-	-	SYM
fnp-2819	117	3	5	5	NUM
fnp-2819	117	4	.	.	PUNCT
fnp-2819	118	1	only	only	ADV
fnp-2819	118	2	the	the	DET
fnp-2819	118	3	differences	difference	NOUN
fnp-2819	118	4	in	in	ADP
fnp-2819	118	5	gene	gene	NOUN
fnp-2819	118	6	expression	expression	NOUN
fnp-2819	118	7	that	that	PRON
fnp-2819	118	8	occur	occur	VERB
fnp-2819	118	9	consecutively	consecutively	ADV
fnp-2819	118	10	at	at	ADP
fnp-2819	118	11	more	more	ADJ
fnp-2819	118	12	than	than	ADP
fnp-2819	118	13	one	one	NUM
fnp-2819	118	14	-	-	PUNCT
fnp-2819	118	15	time	time	NOUN
fnp-2819	118	16	point	point	NOUN
fnp-2819	118	17	but	but	CCONJ
fnp-2819	118	18	not	not	PART
fnp-2819	118	19	those	those	PRON
fnp-2819	118	20	altered	alter	VERB
fnp-2819	118	21	transiently	transiently	ADV
fnp-2819	118	22	or	or	CCONJ
fnp-2819	118	23	sporadically	sporadically	ADV
fnp-2819	118	24	are	be	AUX
fnp-2819	118	25	highlighted	highlight	VERB
fnp-2819	118	26	herein	herein	NOUN
fnp-2819	118	27	.	.	PUNCT
fnp-2819	119	1	longitudinal	longitudinal	ADJ
fnp-2819	119	2	analysis	analysis	NOUN
fnp-2819	119	3	during	during	ADP
fnp-2819	119	4	chronic	chronic	ADJ
fnp-2819	119	5	peae	peae	PROPN
fnp-2819	119	6	revealed	reveal	VERB
fnp-2819	119	7	that	that	SCONJ
fnp-2819	119	8	some	some	DET
fnp-2819	119	9	immune	immune	ADJ
fnp-2819	119	10	response	response	NOUN
fnp-2819	119	11	-	-	PUNCT
fnp-2819	119	12	related	relate	VERB
fnp-2819	119	13	genes	gene	NOUN
fnp-2819	119	14	were	be	AUX
fnp-2819	119	15	induced	induce	VERB
fnp-2819	119	16	upon	upon	SCONJ
fnp-2819	119	17	mog35	mog35	NOUN
fnp-2819	119	18	-	-	PUNCT
fnp-2819	119	19	55	55	NUM
fnp-2819	119	20	immunization	immunization	NOUN
fnp-2819	119	21	after	after	ADP
fnp-2819	119	22	a	a	DET
fnp-2819	119	23	7	7	NUM
fnp-2819	119	24	-	-	SYM
fnp-2819	119	25	14	14	NUM
fnp-2819	119	26	-	-	PUNCT
fnp-2819	119	27	day	day	NOUN
fnp-2819	119	28	lag	lag	NOUN
fnp-2819	119	29	period	period	NOUN
fnp-2819	119	30	in	in	ADP
fnp-2819	119	31	both	both	CCONJ
fnp-2819	119	32	the	the	DET
fnp-2819	119	33	cns	cns	PROPN
fnp-2819	119	34	and	and	CCONJ
fnp-2819	119	35	slo	slo	PROPN
fnp-2819	119	36	.	.	PUNCT
fnp-2819	120	1	the	the	DET
fnp-2819	120	2	th	th	X
fnp-2819	120	3	cell	cell	NOUN
fnp-2819	120	4	-	-	PUNCT
fnp-2819	120	5	associated	associate	VERB
fnp-2819	120	6	il17a	il17a	PROPN
fnp-2819	120	7	,	,	PUNCT
fnp-2819	120	8	il4	il4	ADJ
fnp-2819	120	9	,	,	PUNCT
fnp-2819	120	10	and	and	CCONJ
fnp-2819	120	11	il22	il22	PROPN
fnp-2819	120	12	and	and	CCONJ
fnp-2819	120	13	the	the	DET
fnp-2819	120	14	inflammatory	inflammatory	ADJ
fnp-2819	120	15	cytokine	cytokine	NOUN
fnp-2819	120	16	gene	gene	NOUN
fnp-2819	120	17	nos2	nos2	NOUN
fnp-2819	120	18	were	be	AUX
fnp-2819	120	19	upregulated	upregulate	VERB
fnp-2819	120	20	for	for	ADP
fnp-2819	120	21	a	a	DET
fnp-2819	120	22	prolonged	prolonged	ADJ
fnp-2819	120	23	period	period	NOUN
fnp-2819	120	24	between	between	ADP
fnp-2819	120	25	21	21	NUM
fnp-2819	120	26	and	and	CCONJ
fnp-2819	120	27	54	54	NUM
fnp-2819	120	28	days	day	NOUN
fnp-2819	120	29	in	in	ADP
fnp-2819	120	30	the	the	DET
fnp-2819	120	31	cns	cns	NOUN
fnp-2819	120	32	in	in	ADP
fnp-2819	120	33	different	different	ADJ
fnp-2819	120	34	experiments	experiment	NOUN
fnp-2819	120	35	(	(	PUNCT
fnp-2819	120	36	fig	fig	NOUN
fnp-2819	120	37	.	.	PUNCT
fnp-2819	121	1	2a	2a	NUM
fnp-2819	121	2	-	-	PUNCT
fnp-2819	121	3	d	d	NOUN
fnp-2819	121	4	)	)	PUNCT
fnp-2819	121	5	.	.	PUNCT
fnp-2819	122	1	the	the	DET
fnp-2819	122	2	epigenetic	epigenetic	ADJ
fnp-2819	122	3	drug	drug	NOUN
fnp-2819	122	4	suppressed	suppress	VERB
fnp-2819	122	5	the	the	DET
fnp-2819	122	6	expression	expression	NOUN
fnp-2819	122	7	of	of	ADP
fnp-2819	122	8	these	these	DET
fnp-2819	122	9	genes	gene	NOUN
fnp-2819	122	10	that	that	PRON
fnp-2819	122	11	were	be	AUX
fnp-2819	122	12	upregulated	upregulate	VERB
fnp-2819	122	13	by	by	ADP
fnp-2819	122	14	immunization	immunization	NOUN
fnp-2819	122	15	.	.	PUNCT
fnp-2819	123	1	surprisingly	surprisingly	ADV
fnp-2819	123	2	,	,	PUNCT
fnp-2819	123	3	the	the	DET
fnp-2819	123	4	constitutive	constitutive	ADJ
fnp-2819	123	5	expression	expression	NOUN
fnp-2819	123	6	of	of	ADP
fnp-2819	123	7	mif	mif	PROPN
fnp-2819	123	8	,	,	PUNCT
fnp-2819	123	9	ahr	ahr	PROPN
fnp-2819	123	10	,	,	PUNCT
fnp-2819	123	11	and	and	CCONJ
fnp-2819	123	12	cd274	cd274	PROPN
fnp-2819	123	13	was	be	AUX
fnp-2819	123	14	also	also	ADV
fnp-2819	123	15	notably	notably	ADV
fnp-2819	123	16	repressed	repress	VERB
fnp-2819	123	17	by	by	ADP
fnp-2819	123	18	tsa	tsa	NOUN
fnp-2819	123	19	treatment	treatment	NOUN
fnp-2819	123	20	during	during	ADP
fnp-2819	123	21	the	the	DET
fnp-2819	123	22	chronic	chronic	ADJ
fnp-2819	123	23	phase	phase	NOUN
fnp-2819	123	24	of	of	ADP
fnp-2819	123	25	the	the	DET
fnp-2819	123	26	disease	disease	NOUN
fnp-2819	123	27	(	(	PUNCT
fnp-2819	123	28	fig	fig	NOUN
fnp-2819	123	29	.	.	PUNCT
fnp-2819	124	1	2e	2e	NUM
fnp-2819	124	2	-	-	PUNCT
fnp-2819	124	3	g	g	NOUN
fnp-2819	124	4	)	)	PUNCT
fnp-2819	124	5	.	.	PUNCT
fnp-2819	125	1	unexpectedly	unexpectedly	ADV
fnp-2819	125	2	,	,	PUNCT
fnp-2819	125	3	the	the	DET
fnp-2819	125	4	pan	pan	PROPN
fnp-2819	125	5	hdac	hdac	PROPN
fnp-2819	125	6	inhibitor	inhibitor	PROPN
fnp-2819	125	7	upregulated	upregulate	VERB
fnp-2819	125	8	the	the	DET
fnp-2819	125	9	expression	expression	NOUN
fnp-2819	125	10	of	of	ADP
fnp-2819	125	11	dec1	dec1	PROPN
fnp-2819	125	12	(	(	PUNCT
fnp-2819	125	13	bhlhe40	bhlhe40	ADV
fnp-2819	125	14	)	)	PUNCT
fnp-2819	125	15	,	,	PUNCT
fnp-2819	125	16	specifically	specifically	ADV
fnp-2819	125	17	during	during	ADP
fnp-2819	125	18	the	the	DET
fnp-2819	125	19	late	late	ADJ
fnp-2819	125	20	stage	stage	NOUN
fnp-2819	125	21	of	of	ADP
fnp-2819	125	22	peae	peae	PROPN
fnp-2819	125	23	(	(	PUNCT
fnp-2819	125	24	fig	fig	NOUN
fnp-2819	125	25	.	.	PUNCT
fnp-2819	126	1	2h	2h	NUM
fnp-2819	126	2	)	)	PUNCT
fnp-2819	126	3	.	.	PUNCT
fnp-2819	127	1	fig	fig	NOUN
fnp-2819	127	2	.	.	PUNCT
fnp-2819	128	1	2	2	NUM
fnp-2819	128	2	differential	differential	NOUN
fnp-2819	128	3	impact	impact	NOUN
fnp-2819	128	4	of	of	ADP
fnp-2819	128	5	the	the	DET
fnp-2819	128	6	histone	histone	NOUN
fnp-2819	128	7	modifier	modifier	NOUN
fnp-2819	128	8	on	on	ADP
fnp-2819	128	9	gene	gene	NOUN
fnp-2819	128	10	expression	expression	NOUN
fnp-2819	128	11	in	in	ADP
fnp-2819	128	12	the	the	DET
fnp-2819	128	13	cns	cns	NOUN
fnp-2819	128	14	.	.	PUNCT
fnp-2819	128	15	  	  	SPACE
fnp-2819	128	16	total	total	ADJ
fnp-2819	128	17	rna	rna	NOUN
fnp-2819	128	18	was	be	AUX
fnp-2819	128	19	extracted	extract	VERB
fnp-2819	128	20	individually	individually	ADV
fnp-2819	128	21	from	from	ADP
fnp-2819	128	22	five	five	NUM
fnp-2819	128	23	mice	mouse	NOUN
fnp-2819	128	24	per	per	ADP
fnp-2819	128	25	group	group	NOUN
fnp-2819	128	26	from	from	ADP
fnp-2819	128	27	the	the	DET
fnp-2819	128	28	spinal	spinal	ADJ
fnp-2819	128	29	cord	cord	NOUN
fnp-2819	128	30	(	(	PUNCT
fnp-2819	128	31	sc	sc	PROPN
fnp-2819	128	32	)	)	PUNCT
fnp-2819	128	33	at	at	ADP
fnp-2819	128	34	various	various	ADJ
fnp-2819	128	35	time	time	NOUN
fnp-2819	128	36	points	point	NOUN
fnp-2819	128	37	.	.	PUNCT
fnp-2819	129	1	at	at	ADP
fnp-2819	129	2	each	each	DET
fnp-2819	129	3	time	time	NOUN
fnp-2819	129	4	point	point	NOUN
fnp-2819	129	5	,	,	PUNCT
fnp-2819	129	6	rna	rna	PROPN
fnp-2819	129	7	pooled	pool	VERB
fnp-2819	129	8	from	from	ADP
fnp-2819	129	9	five	five	NUM
fnp-2819	129	10	mice	mouse	NOUN
fnp-2819	129	11	/	/	SYM
fnp-2819	129	12	group	group	NOUN
fnp-2819	129	13	was	be	AUX
fnp-2819	129	14	analyzed	analyze	VERB
fnp-2819	129	15	in	in	ADP
fnp-2819	129	16	triplicate	triplicate	NOUN
fnp-2819	129	17	.	.	PUNCT
fnp-2819	130	1	the	the	DET
fnp-2819	130	2	expression	expression	NOUN
fnp-2819	130	3	of	of	ADP
fnp-2819	130	4	indicated	indicate	VERB
fnp-2819	130	5	genes	gene	NOUN
fnp-2819	130	6	was	be	AUX
fnp-2819	130	7	normalized	normalize	VERB
fnp-2819	130	8	to	to	ADP
fnp-2819	130	9	the	the	DET
fnp-2819	130	10	housekeeping	housekeeping	NOUN
fnp-2819	130	11	gene	gene	NOUN
fnp-2819	130	12	,	,	PUNCT
fnp-2819	130	13	gapdh	gapdh	NOUN
fnp-2819	130	14	,	,	PUNCT
fnp-2819	130	15	and	and	CCONJ
fnp-2819	130	16	depicted	depict	VERB
fnp-2819	130	17	as	as	ADP
fnp-2819	130	18	mean	mean	PROPN
fnp-2819	130	19	±	±	NUM
fnp-2819	130	20	sem	sem	NOUN
fnp-2819	130	21	of	of	ADP
fnp-2819	130	22	triplicate	triplicate	NOUN
fnp-2819	130	23	samples	sample	NOUN
fnp-2819	130	24	.	.	PUNCT
fnp-2819	131	1	statistical	statistical	ADJ
fnp-2819	131	2	significance	significance	NOUN
fnp-2819	131	3	(	(	PUNCT
fnp-2819	131	4	p<0.05	p<0.05	NOUN
fnp-2819	131	5	)	)	PUNCT
fnp-2819	131	6	between	between	ADP
fnp-2819	131	7	dmso	dmso	NOUN
fnp-2819	131	8	(	(	PUNCT
fnp-2819	131	9	blank	blank	ADJ
fnp-2819	131	10	bars	bar	NOUN
fnp-2819	131	11	)	)	PUNCT
fnp-2819	131	12	and	and	CCONJ
fnp-2819	131	13	drug	drug	NOUN
fnp-2819	131	14	-	-	PUNCT
fnp-2819	131	15	treated	treat	VERB
fnp-2819	131	16	mice	mouse	NOUN
fnp-2819	131	17	(	(	PUNCT
fnp-2819	131	18	hatched	hatch	VERB
fnp-2819	131	19	bars	bar	NOUN
fnp-2819	131	20	)	)	PUNCT
fnp-2819	131	21	was	be	AUX
fnp-2819	131	22	determined	determine	VERB
fnp-2819	131	23	using	use	VERB
fnp-2819	131	24	an	an	DET
fnp-2819	131	25	unpaired	unpaired	ADJ
fnp-2819	131	26	two	two	NUM
fnp-2819	131	27	-	-	PUNCT
fnp-2819	131	28	tailed	tail	VERB
fnp-2819	131	29	t	t	NOUN
fnp-2819	131	30	-	-	PUNCT
fnp-2819	131	31	test	test	NOUN
fnp-2819	131	32	and	and	CCONJ
fnp-2819	131	33	indicated	indicate	VERB
fnp-2819	131	34	by	by	ADP
fnp-2819	131	35	asterisks	asterisk	NOUN
fnp-2819	131	36	.	.	PUNCT
fnp-2819	132	1	individual	individual	ADJ
fnp-2819	132	2	replicates	replicate	NOUN
fnp-2819	132	3	for	for	ADP
fnp-2819	132	4	dmso	dmso	NOUN
fnp-2819	132	5	(	(	PUNCT
fnp-2819	132	6	empty	empty	ADJ
fnp-2819	132	7	circles	circle	NOUN
fnp-2819	132	8	)	)	PUNCT
fnp-2819	132	9	and	and	CCONJ
fnp-2819	132	10	tsa	tsa	NOUN
fnp-2819	132	11	-	-	PUNCT
fnp-2819	132	12	treated	treat	VERB
fnp-2819	132	13	samples	sample	NOUN
fnp-2819	132	14	(	(	PUNCT
fnp-2819	132	15	empty	empty	ADJ
fnp-2819	132	16	squares	square	NOUN
fnp-2819	132	17	)	)	PUNCT
fnp-2819	132	18	are	be	AUX
fnp-2819	132	19	also	also	ADV
fnp-2819	132	20	shown	show	VERB
fnp-2819	132	21	.	.	PUNCT
fnp-2819	133	1	unimmunized	unimmunized	ADJ
fnp-2819	133	2	mice	mouse	NOUN
fnp-2819	133	3	(	(	PUNCT
fnp-2819	133	4	10	10	NUM
fnp-2819	133	5	/	/	SYM
fnp-2819	133	6	group	group	NOUN
fnp-2819	133	7	)	)	PUNCT
fnp-2819	133	8	were	be	AUX
fnp-2819	133	9	treated	treat	VERB
fnp-2819	133	10	with	with	ADP
fnp-2819	133	11	dmso	dmso	NOUN
fnp-2819	133	12	or	or	CCONJ
fnp-2819	133	13	tsa	tsa	NOUN
fnp-2819	133	14	and	and	CCONJ
fnp-2819	133	15	analyzed	analyze	VERB
fnp-2819	133	16	one	one	NUM
fnp-2819	133	17	day	day	NOUN
fnp-2819	133	18	later	later	ADV
fnp-2819	133	19	for	for	SCONJ
fnp-2819	133	20	the	the	DET
fnp-2819	133	21	effect	effect	NOUN
fnp-2819	133	22	of	of	ADP
fnp-2819	133	23	drug	drug	NOUN
fnp-2819	133	24	treatment	treatment	NOUN
fnp-2819	133	25	on	on	ADP
fnp-2819	133	26	the	the	DET
fnp-2819	133	27	basal	basal	ADJ
fnp-2819	133	28	level	level	NOUN
fnp-2819	133	29	expression	expression	NOUN
fnp-2819	133	30	of	of	ADP
fnp-2819	133	31	genes	gene	NOUN
fnp-2819	133	32	irrespective	irrespective	ADV
fnp-2819	133	33	of	of	ADP
fnp-2819	133	34	immunization	immunization	NOUN
fnp-2819	133	35	.	.	PUNCT
fnp-2819	134	1	although	although	SCONJ
fnp-2819	134	2	previous	previous	ADJ
fnp-2819	134	3	studies	study	NOUN
fnp-2819	134	4	implicated	implicate	VERB
fnp-2819	134	5	many	many	ADJ
fnp-2819	134	6	other	other	ADJ
fnp-2819	134	7	genes	gene	NOUN
fnp-2819	134	8	in	in	ADP
fnp-2819	134	9	eae	eae	PROPN
fnp-2819	134	10	,	,	PUNCT
fnp-2819	134	11	those	those	PRON
fnp-2819	134	12	encoding	encode	VERB
fnp-2819	134	13	il-23	il-23	NOUN
fnp-2819	134	14	,	,	PUNCT
fnp-2819	134	15	ifn	ifn	PROPN
fnp-2819	134	16	-	-	PUNCT
fnp-2819	134	17	γ	γ	NOUN
fnp-2819	134	18	,	,	PUNCT
fnp-2819	134	19	il-18	il-18	ADP
fnp-2819	134	20	,	,	PUNCT
fnp-2819	134	21	il-27p28	il-27p28	NOUN
fnp-2819	134	22	,	,	PUNCT
fnp-2819	134	23	il-27ebi3	il-27ebi3	NOUN
fnp-2819	134	24	,	,	PUNCT
fnp-2819	134	25	il-12p35	il-12p35	PROPN
fnp-2819	134	26	,	,	PUNCT
fnp-2819	134	27	il-10	il-10	PRON
fnp-2819	134	28	,	,	PUNCT
fnp-2819	134	29	gm	gm	PROPN
fnp-2819	134	30	-	-	PUNCT
fnp-2819	134	31	csf	csf	PROPN
fnp-2819	134	32	,	,	PUNCT
fnp-2819	134	33	tnf	tnf	PROPN
fnp-2819	134	34	-	-	PUNCT
fnp-2819	134	35	α	α	PROPN
fnp-2819	134	36	,	,	PUNCT
fnp-2819	134	37	and	and	CCONJ
fnp-2819	134	38	tgf	tgf	PROPN
fnp-2819	134	39	-	-	PUNCT
fnp-2819	134	40	β	β	PROPN
fnp-2819	134	41	were	be	AUX
fnp-2819	134	42	not	not	PART
fnp-2819	134	43	transcriptionally	transcriptionally	ADV
fnp-2819	134	44	upregulated	upregulate	VERB
fnp-2819	134	45	in	in	ADP
fnp-2819	134	46	the	the	DET
fnp-2819	134	47	cns	cns	NOUN
fnp-2819	134	48	of	of	ADP
fnp-2819	134	49	peae	peae	PROPN
fnp-2819	134	50	mice	mouse	NOUN
fnp-2819	134	51	(	(	PUNCT
fnp-2819	134	52	see	see	VERB
fnp-2819	134	53	supplementary	supplementary	ADJ
fnp-2819	134	54	fig	fig	NOUN
fnp-2819	134	55	.	.	PUNCT
fnp-2819	135	1	1	1	NUM
fnp-2819	135	2	-	-	SYM
fnp-2819	135	3	2	2	NUM
fnp-2819	135	4	)	)	PUNCT
fnp-2819	135	5	.	.	PUNCT
fnp-2819	136	1	similarly	similarly	ADV
fnp-2819	136	2	,	,	PUNCT
fnp-2819	136	3	the	the	DET
fnp-2819	136	4	mrna	mrna	NOUN
fnp-2819	136	5	of	of	ADP
fnp-2819	136	6	the	the	DET
fnp-2819	136	7	accessory	accessory	NOUN
fnp-2819	136	8	cell	cell	NOUN
fnp-2819	136	9	surface	surface	NOUN
fnp-2819	136	10	-	-	PUNCT
fnp-2819	136	11	associated	associate	VERB
fnp-2819	136	12	determinants	determinant	NOUN
fnp-2819	136	13	,	,	PUNCT
fnp-2819	136	14	mmp9	mmp9	ADJ
fnp-2819	136	15	,	,	PUNCT
fnp-2819	136	16	mmp12	mmp12	ADJ
fnp-2819	136	17	,	,	PUNCT
fnp-2819	136	18	and	and	CCONJ
fnp-2819	136	19	cd74	cd74	PROPN
fnp-2819	136	20	,	,	PUNCT
fnp-2819	136	21	remained	remain	VERB
fnp-2819	136	22	stable	stable	ADJ
fnp-2819	136	23	in	in	ADP
fnp-2819	136	24	the	the	DET
fnp-2819	136	25	cns	cns	NOUN
fnp-2819	136	26	following	follow	VERB
fnp-2819	136	27	immunization	immunization	NOUN
fnp-2819	136	28	(	(	PUNCT
fnp-2819	136	29	supplementary	supplementary	ADJ
fnp-2819	136	30	fig	fig	NOUN
fnp-2819	136	31	.	.	PUNCT
fnp-2819	137	1	3	3	NUM
fnp-2819	137	2	)	)	PUNCT
fnp-2819	137	3	.	.	PUNCT
fnp-2819	138	1	moreover	moreover	ADV
fnp-2819	138	2	,	,	PUNCT
fnp-2819	138	3	the	the	DET
fnp-2819	138	4	transcription	transcription	NOUN
fnp-2819	138	5	factor	factor	NOUN
fnp-2819	138	6	genes	gene	NOUN
fnp-2819	138	7	such	such	ADJ
fnp-2819	138	8	as	as	ADP
fnp-2819	138	9	tbet	tbet	NOUN
fnp-2819	138	10	,	,	PUNCT
fnp-2819	138	11	gata3	gata3	PROPN
fnp-2819	138	12	,	,	PUNCT
fnp-2819	138	13	rorgt	rorgt	NOUN
fnp-2819	138	14	,	,	PUNCT
fnp-2819	138	15	eomes	eome	NOUN
fnp-2819	138	16	,	,	PUNCT
fnp-2819	138	17	and	and	CCONJ
fnp-2819	138	18	foxp3	foxp3	NOUN
fnp-2819	138	19	also	also	ADV
fnp-2819	138	20	remained	remain	VERB
fnp-2819	138	21	unchanged	unchanged	ADJ
fnp-2819	138	22	in	in	ADP
fnp-2819	138	23	the	the	DET
fnp-2819	138	24	sc	sc	PROPN
fnp-2819	138	25	(	(	PUNCT
fnp-2819	138	26	supplementary	supplementary	ADJ
fnp-2819	138	27	fig	fig	NOUN
fnp-2819	138	28	.	.	PUNCT
fnp-2819	139	1	4	4	NUM
fnp-2819	139	2	)	)	PUNCT
fnp-2819	139	3	.	.	PUNCT
fnp-2819	140	1	notably	notably	ADV
fnp-2819	140	2	,	,	PUNCT
fnp-2819	140	3	the	the	DET
fnp-2819	140	4	histone	histone	NOUN
fnp-2819	140	5	modifier	modifier	NOUN
fnp-2819	140	6	failed	fail	VERB
fnp-2819	140	7	to	to	PART
fnp-2819	140	8	alter	alter	VERB
fnp-2819	140	9	the	the	DET
fnp-2819	140	10	transcription	transcription	NOUN
fnp-2819	140	11	of	of	ADP
fnp-2819	140	12	these	these	DET
fnp-2819	140	13	genes	gene	NOUN
fnp-2819	140	14	.	.	PUNCT
fnp-2819	141	1	thus	thus	ADV
fnp-2819	141	2	,	,	PUNCT
fnp-2819	141	3	our	our	PRON
fnp-2819	141	4	comprehensive	comprehensive	ADJ
fnp-2819	141	5	analysis	analysis	NOUN
fnp-2819	141	6	uncovered	uncover	VERB
fnp-2819	141	7	the	the	DET
fnp-2819	141	8	selective	selective	ADJ
fnp-2819	141	9	repression	repression	NOUN
fnp-2819	141	10	of	of	ADP
fnp-2819	141	11	genes	gene	NOUN
fnp-2819	141	12	in	in	ADP
fnp-2819	141	13	the	the	DET
fnp-2819	141	14	cns	cns	NOUN
fnp-2819	141	15	without	without	ADP
fnp-2819	141	16	affecting	affect	VERB
fnp-2819	141	17	the	the	DET
fnp-2819	141	18	levels	level	NOUN
fnp-2819	141	19	of	of	ADP
fnp-2819	141	20	many	many	ADJ
fnp-2819	141	21	other	other	ADJ
fnp-2819	141	22	genes	gene	NOUN
fnp-2819	141	23	previously	previously	ADV
fnp-2819	141	24	implicated	implicate	VERB
fnp-2819	141	25	in	in	ADP
fnp-2819	141	26	neuroinflammation	neuroinflammation	NOUN
fnp-2819	141	27	.	.	PUNCT
fnp-2819	142	1	3.3	3.3	NUM
fnp-2819	142	2	.	.	PUNCT
fnp-2819	143	1	the	the	DET
fnp-2819	143	2	different	different	ADJ
fnp-2819	143	3	patterns	pattern	NOUN
fnp-2819	143	4	of	of	ADP
fnp-2819	143	5	gene	gene	NOUN
fnp-2819	143	6	regulation	regulation	NOUN
fnp-2819	143	7	in	in	ADP
fnp-2819	143	8	the	the	DET
fnp-2819	143	9	slo	slo	PROPN
fnp-2819	143	10	by	by	ADP
fnp-2819	143	11	tsa	tsa	NOUN
fnp-2819	143	12	treatment	treatment	NOUN
fnp-2819	143	13	the	the	DET
fnp-2819	143	14	expression	expression	NOUN
fnp-2819	143	15	of	of	ADP
fnp-2819	143	16	the	the	DET
fnp-2819	143	17	genes	gene	NOUN
fnp-2819	143	18	encoding	encode	VERB
fnp-2819	143	19	the	the	DET
fnp-2819	143	20	subunits	subunit	NOUN
fnp-2819	143	21	of	of	ADP
fnp-2819	143	22	the	the	DET
fnp-2819	143	23	heterodimeric	heterodimeric	ADJ
fnp-2819	143	24	lymphokine	lymphokine	NOUN
fnp-2819	143	25	il-27	il-27	PRON
fnp-2819	143	26	such	such	ADJ
fnp-2819	143	27	as	as	ADP
fnp-2819	143	28	il-27p28	il-27p28	NOUN
fnp-2819	143	29	and	and	CCONJ
fnp-2819	143	30	il-27ebi3	il-27ebi3	NOUN
fnp-2819	143	31	peaked	peak	VERB
fnp-2819	143	32	on	on	ADP
fnp-2819	143	33	day	day	NOUN
fnp-2819	143	34	21	21	NUM
fnp-2819	143	35	and	and	CCONJ
fnp-2819	143	36	subsided	subside	VERB
fnp-2819	143	37	steadily	steadily	ADV
fnp-2819	143	38	thereafter	thereafter	ADV
fnp-2819	143	39	in	in	ADP
fnp-2819	143	40	the	the	DET
fnp-2819	143	41	slo	slo	PROPN
fnp-2819	143	42	(	(	PUNCT
fnp-2819	143	43	fig	fig	NOUN
fnp-2819	143	44	.	.	PUNCT
fnp-2819	144	1	3a	3a	NUM
fnp-2819	144	2	-	-	SYM
fnp-2819	144	3	b	b	NOUN
fnp-2819	144	4	)	)	PUNCT
fnp-2819	144	5	.	.	PUNCT
fnp-2819	145	1	treatment	treatment	NOUN
fnp-2819	145	2	with	with	ADP
fnp-2819	145	3	tsa	tsa	NOUN
fnp-2819	145	4	reduced	reduce	VERB
fnp-2819	145	5	the	the	DET
fnp-2819	145	6	expression	expression	NOUN
fnp-2819	145	7	of	of	ADP
fnp-2819	145	8	these	these	DET
fnp-2819	145	9	genes	gene	NOUN
fnp-2819	145	10	and	and	CCONJ
fnp-2819	145	11	the	the	DET
fnp-2819	145	12	inflammatory	inflammatory	ADJ
fnp-2819	145	13	gene	gene	NOUN
fnp-2819	145	14	nos2	nos2	NOUN
fnp-2819	145	15	(	(	PUNCT
fnp-2819	145	16	fig	fig	NOUN
fnp-2819	145	17	.	.	PUNCT
fnp-2819	146	1	3c	3c	NUM
fnp-2819	146	2	)	)	PUNCT
fnp-2819	146	3	.	.	PUNCT
fnp-2819	147	1	interestingly	interestingly	ADV
fnp-2819	147	2	,	,	PUNCT
fnp-2819	147	3	the	the	DET
fnp-2819	147	4	transcription	transcription	NOUN
fnp-2819	147	5	of	of	ADP
fnp-2819	147	6	mif	mif	PROPN
fnp-2819	147	7	,	,	PUNCT
fnp-2819	147	8	cd274	cd274	PROPN
fnp-2819	147	9	,	,	PUNCT
fnp-2819	147	10	and	and	CCONJ
fnp-2819	147	11	cd39	cd39	PROPN
fnp-2819	147	12	in	in	ADP
fnp-2819	147	13	the	the	DET
fnp-2819	147	14	slo	slo	PROPN
fnp-2819	147	15	was	be	AUX
fnp-2819	147	16	also	also	ADV
fnp-2819	147	17	downregulated	downregulate	VERB
fnp-2819	147	18	by	by	ADP
fnp-2819	147	19	the	the	DET
fnp-2819	147	20	histone	histone	NOUN
fnp-2819	147	21	modifier	modifier	NOUN
fnp-2819	147	22	(	(	PUNCT
fnp-2819	147	23	fig	fig	NOUN
fnp-2819	147	24	.	.	PUNCT
fnp-2819	148	1	3d	3d	NUM
fnp-2819	148	2	-	-	PUNCT
fnp-2819	148	3	f	f	NOUN
fnp-2819	148	4	)	)	PUNCT
fnp-2819	148	5	.	.	PUNCT
fnp-2819	149	1	surprisingly	surprisingly	ADV
fnp-2819	149	2	,	,	PUNCT
fnp-2819	149	3	the	the	DET
fnp-2819	149	4	genes	gene	NOUN
fnp-2819	149	5	encoding	encode	VERB
fnp-2819	149	6	the	the	DET
fnp-2819	149	7	lymphokines	lymphokine	NOUN
fnp-2819	149	8	such	such	ADJ
fnp-2819	149	9	as	as	ADP
fnp-2819	149	10	il-4	il-4	NOUN
fnp-2819	149	11	,	,	PUNCT
fnp-2819	149	12	il-10	il-10	PRON
fnp-2819	149	13	,	,	PUNCT
fnp-2819	149	14	il-17a	il-17a	PROPN
fnp-2819	149	15	,	,	PUNCT
fnp-2819	149	16	il-12p35	il-12p35	PROPN
fnp-2819	149	17	,	,	PUNCT
fnp-2819	149	18	il-18	il-18	PRON
fnp-2819	149	19	,	,	PUNCT
fnp-2819	149	20	il-22	il-22	NOUN
fnp-2819	149	21	,	,	PUNCT
fnp-2819	149	22	il-23	il-23	NOUN
fnp-2819	149	23	,	,	PUNCT
fnp-2819	149	24	ifn	ifn	PROPN
fnp-2819	149	25	-	-	PUNCT
fnp-2819	149	26	γ	γ	NOUN
fnp-2819	149	27	,	,	PUNCT
fnp-2819	149	28	tgfβ	tgfβ	ADJ
fnp-2819	149	29	,	,	PUNCT
fnp-2819	149	30	gm	gm	PROPN
fnp-2819	149	31	-	-	PUNCT
fnp-2819	149	32	csf	csf	ADJ
fnp-2819	149	33	and	and	CCONJ
fnp-2819	149	34	tnf	tnf	PROPN
fnp-2819	149	35	-	-	PUNCT
fnp-2819	149	36	α	α	PROPN
fnp-2819	149	37	(	(	PUNCT
fnp-2819	149	38	supplementary	supplementary	ADJ
fnp-2819	149	39	fig	fig	NOUN
fnp-2819	149	40	.	.	PUNCT
fnp-2819	150	1	1	1	NUM
fnp-2819	150	2	-	-	SYM
fnp-2819	150	3	2	2	NUM
fnp-2819	150	4	)	)	PUNCT
fnp-2819	150	5	,	,	PUNCT
fnp-2819	150	6	as	as	ADV
fnp-2819	150	7	well	well	ADV
fnp-2819	150	8	as	as	ADP
fnp-2819	150	9	the	the	DET
fnp-2819	150	10	macrophage	macrophage	NOUN
fnp-2819	150	11	-	-	PUNCT
fnp-2819	150	12	associated	associate	VERB
fnp-2819	150	13	determinants	determinant	NOUN
fnp-2819	150	14	,	,	PUNCT
fnp-2819	150	15	mmp9	mmp9	PROPN
fnp-2819	150	16	,	,	PUNCT
fnp-2819	150	17	mmp12	mmp12	ADJ
fnp-2819	150	18	,	,	PUNCT
fnp-2819	150	19	arg-1	arg-1	X
fnp-2819	150	20	,	,	PUNCT
fnp-2819	150	21	and	and	CCONJ
fnp-2819	150	22	cd74	cd74	PROPN
fnp-2819	150	23	were	be	AUX
fnp-2819	150	24	neither	neither	CCONJ
fnp-2819	150	25	upregulated	upregulate	VERB
fnp-2819	150	26	during	during	ADP
fnp-2819	150	27	pathogenesis	pathogenesis	NOUN
fnp-2819	150	28	nor	nor	CCONJ
fnp-2819	150	29	repressed	repress	VERB
fnp-2819	150	30	by	by	ADP
fnp-2819	150	31	tsa	tsa	NOUN
fnp-2819	150	32	treatment	treatment	NOUN
fnp-2819	150	33	in	in	ADP
fnp-2819	150	34	the	the	DET
fnp-2819	150	35	slo	slo	PROPN
fnp-2819	150	36	(	(	PUNCT
fnp-2819	150	37	supplementary	supplementary	ADJ
fnp-2819	150	38	fig	fig	NOUN
fnp-2819	150	39	.	.	PUNCT
fnp-2819	151	1	3	3	NUM
fnp-2819	151	2	)	)	PUNCT
fnp-2819	151	3	.	.	PUNCT
fnp-2819	152	1	similarly	similarly	ADV
fnp-2819	152	2	,	,	PUNCT
fnp-2819	152	3	the	the	DET
fnp-2819	152	4	transcription	transcription	NOUN
fnp-2819	152	5	of	of	ADP
fnp-2819	152	6	tbet	tbet	NOUN
fnp-2819	152	7	,	,	PUNCT
fnp-2819	152	8	rorgt	rorgt	NOUN
fnp-2819	152	9	,	,	PUNCT
fnp-2819	152	10	gata3	gata3	PROPN
fnp-2819	152	11	,	,	PUNCT
fnp-2819	152	12	eomes	eome	NOUN
fnp-2819	152	13	,	,	PUNCT
fnp-2819	152	14	dec1	dec1	PROPN
fnp-2819	152	15	,	,	PUNCT
fnp-2819	152	16	ahr	ahr	PROPN
fnp-2819	152	17	,	,	PUNCT
fnp-2819	152	18	and	and	CCONJ
fnp-2819	152	19	foxp3	foxp3	NOUN
fnp-2819	152	20	remained	remain	VERB
fnp-2819	152	21	mostly	mostly	ADV
fnp-2819	152	22	unaffected	unaffected	ADJ
fnp-2819	152	23	by	by	ADP
fnp-2819	152	24	the	the	DET
fnp-2819	152	25	hdac	hdac	NOUN
fnp-2819	152	26	inhibitor	inhibitor	NOUN
fnp-2819	152	27	treatment	treatment	NOUN
fnp-2819	152	28	(	(	PUNCT
fnp-2819	152	29	supplementary	supplementary	ADJ
fnp-2819	152	30	fig	fig	NOUN
fnp-2819	152	31	.	.	PUNCT
fnp-2819	153	1	4	4	NUM
fnp-2819	153	2	)	)	PUNCT
fnp-2819	153	3	.	.	PUNCT
fnp-2819	154	1	thus	thus	ADV
fnp-2819	154	2	,	,	PUNCT
fnp-2819	154	3	the	the	DET
fnp-2819	154	4	antigen	antigen	ADV
fnp-2819	154	5	-	-	PUNCT
fnp-2819	154	6	induced	induce	VERB
fnp-2819	154	7	transcription	transcription	NOUN
fnp-2819	154	8	of	of	ADP
fnp-2819	154	9	il27p28	il27p28	PROPN
fnp-2819	154	10	,	,	PUNCT
fnp-2819	154	11	il27ebi3	il27ebi3	NOUN
fnp-2819	154	12	,	,	PUNCT
fnp-2819	154	13	and	and	CCONJ
fnp-2819	154	14	nos2	nos2	NOUN
fnp-2819	154	15	,	,	PUNCT
fnp-2819	154	16	as	as	ADV
fnp-2819	154	17	well	well	ADV
fnp-2819	154	18	as	as	ADP
fnp-2819	154	19	the	the	DET
fnp-2819	154	20	constitutive	constitutive	ADJ
fnp-2819	154	21	expression	expression	NOUN
fnp-2819	154	22	of	of	ADP
fnp-2819	154	23	mif	mif	PROPN
fnp-2819	154	24	,	,	PUNCT
fnp-2819	154	25	cd274	cd274	PROPN
fnp-2819	154	26	,	,	PUNCT
fnp-2819	154	27	and	and	CCONJ
fnp-2819	154	28	cd39	cd39	PROPN
fnp-2819	154	29	,	,	PUNCT
fnp-2819	154	30	were	be	AUX
fnp-2819	154	31	selectively	selectively	ADV
fnp-2819	154	32	impeded	impede	VERB
fnp-2819	154	33	by	by	ADP
fnp-2819	154	34	tsa	tsa	NOUN
fnp-2819	154	35	treatment	treatment	NOUN
fnp-2819	154	36	in	in	ADP
fnp-2819	154	37	the	the	DET
fnp-2819	154	38	slo	slo	PROPN
fnp-2819	154	39	.	.	PUNCT
fnp-2819	155	1	these	these	DET
fnp-2819	155	2	data	datum	NOUN
fnp-2819	155	3	collectively	collectively	ADV
fnp-2819	155	4	demonstrate	demonstrate	VERB
fnp-2819	155	5	the	the	DET
fnp-2819	155	6	differential	differential	ADJ
fnp-2819	155	7	influence	influence	NOUN
fnp-2819	155	8	of	of	ADP
fnp-2819	155	9	epigenetic	epigenetic	ADJ
fnp-2819	155	10	modulation	modulation	NOUN
fnp-2819	155	11	on	on	ADP
fnp-2819	155	12	gene	gene	NOUN
fnp-2819	155	13	expression	expression	NOUN
fnp-2819	155	14	in	in	ADP
fnp-2819	155	15	the	the	DET
fnp-2819	155	16	cns	cns	NOUN
fnp-2819	155	17	and	and	CCONJ
fnp-2819	155	18	slo	slo	PROPN
fnp-2819	155	19	in	in	ADP
fnp-2819	155	20	the	the	DET
fnp-2819	155	21	peae	peae	PROPN
fnp-2819	155	22	model	model	NOUN
fnp-2819	155	23	.	.	PUNCT
fnp-2819	156	1	fig	fig	NOUN
fnp-2819	156	2	.	.	PUNCT
fnp-2819	157	1	3	3	NUM
fnp-2819	157	2	different	different	ADJ
fnp-2819	157	3	patterns	pattern	NOUN
fnp-2819	157	4	of	of	ADP
fnp-2819	157	5	gene	gene	NOUN
fnp-2819	157	6	regulation	regulation	NOUN
fnp-2819	157	7	in	in	ADP
fnp-2819	157	8	the	the	DET
fnp-2819	157	9	slo	slo	PROPN
fnp-2819	157	10	by	by	ADP
fnp-2819	157	11	tsa	tsa	NOUN
fnp-2819	157	12	treatment	treatment	NOUN
fnp-2819	157	13	.	.	PUNCT
fnp-2819	157	14	  	  	SPACE
fnp-2819	158	1	expression	expression	NOUN
fnp-2819	158	2	levels	level	NOUN
fnp-2819	158	3	of	of	ADP
fnp-2819	158	4	indicated	indicate	VERB
fnp-2819	158	5	genes	gene	NOUN
fnp-2819	158	6	were	be	AUX
fnp-2819	158	7	determined	determine	VERB
fnp-2819	158	8	in	in	ADP
fnp-2819	158	9	control	control	NOUN
fnp-2819	158	10	dmso	dmso	NOUN
fnp-2819	158	11	(	(	PUNCT
fnp-2819	158	12	blank	blank	ADJ
fnp-2819	158	13	bars	bar	NOUN
fnp-2819	158	14	)	)	PUNCT
fnp-2819	158	15	and	and	CCONJ
fnp-2819	158	16	tsa	tsa	NOUN
fnp-2819	158	17	-	-	PUNCT
fnp-2819	158	18	treated	treat	VERB
fnp-2819	158	19	mice	mouse	NOUN
fnp-2819	158	20	(	(	PUNCT
fnp-2819	158	21	hatched	hatch	VERB
fnp-2819	158	22	bars	bar	NOUN
fnp-2819	158	23	)	)	PUNCT
fnp-2819	158	24	using	use	VERB
fnp-2819	158	25	the	the	DET
fnp-2819	158	26	total	total	ADJ
fnp-2819	158	27	rna	rna	NOUN
fnp-2819	158	28	derived	derive	VERB
fnp-2819	158	29	from	from	ADP
fnp-2819	158	30	the	the	DET
fnp-2819	158	31	spleen	spleen	NOUN
fnp-2819	158	32	and	and	CCONJ
fnp-2819	158	33	draining	drain	VERB
fnp-2819	158	34	lymph	lymph	NOUN
fnp-2819	158	35	nodes	node	NOUN
fnp-2819	158	36	(	(	PUNCT
fnp-2819	158	37	sp	sp	NOUN
fnp-2819	158	38	)	)	PUNCT
fnp-2819	158	39	from	from	ADP
fnp-2819	158	40	individual	individual	ADJ
fnp-2819	158	41	mice	mouse	NOUN
fnp-2819	158	42	at	at	ADP
fnp-2819	158	43	the	the	DET
fnp-2819	158	44	indicated	indicate	VERB
fnp-2819	158	45	time	time	NOUN
fnp-2819	158	46	points	point	NOUN
fnp-2819	158	47	.	.	PUNCT
fnp-2819	159	1	at	at	ADP
fnp-2819	159	2	each	each	DET
fnp-2819	159	3	time	time	NOUN
fnp-2819	159	4	point	point	NOUN
fnp-2819	159	5	,	,	PUNCT
fnp-2819	159	6	rna	rna	PROPN
fnp-2819	159	7	pooled	pool	VERB
fnp-2819	159	8	from	from	ADP
fnp-2819	159	9	five	five	NUM
fnp-2819	159	10	mice	mouse	NOUN
fnp-2819	159	11	/	/	SYM
fnp-2819	159	12	group	group	NOUN
fnp-2819	159	13	was	be	AUX
fnp-2819	159	14	analyzed	analyze	VERB
fnp-2819	159	15	in	in	ADP
fnp-2819	159	16	triplicate	triplicate	NOUN
fnp-2819	159	17	.	.	PUNCT
fnp-2819	160	1	individual	individual	ADJ
fnp-2819	160	2	data	datum	NOUN
fnp-2819	160	3	points	point	NOUN
fnp-2819	160	4	for	for	ADP
fnp-2819	160	5	dmso	dmso	NOUN
fnp-2819	160	6	(	(	PUNCT
fnp-2819	160	7	empty	empty	ADJ
fnp-2819	160	8	circles	circle	NOUN
fnp-2819	160	9	)	)	PUNCT
fnp-2819	160	10	and	and	CCONJ
fnp-2819	160	11	tsa	tsa	NOUN
fnp-2819	160	12	-	-	PUNCT
fnp-2819	160	13	treated	treat	VERB
fnp-2819	160	14	(	(	PUNCT
fnp-2819	160	15	empty	empty	ADJ
fnp-2819	160	16	squares	square	NOUN
fnp-2819	160	17	)	)	PUNCT
fnp-2819	160	18	are	be	AUX
fnp-2819	160	19	shown	show	VERB
fnp-2819	160	20	.	.	PUNCT
fnp-2819	161	1	gene	gene	NOUN
fnp-2819	161	2	expression	expression	NOUN
fnp-2819	161	3	was	be	AUX
fnp-2819	161	4	normalized	normalize	VERB
fnp-2819	161	5	to	to	ADP
fnp-2819	161	6	the	the	DET
fnp-2819	161	7	housekeeping	housekeeping	NOUN
fnp-2819	161	8	gene	gene	NOUN
fnp-2819	161	9	,	,	PUNCT
fnp-2819	161	10	gapdh	gapdh	NOUN
fnp-2819	161	11	,	,	PUNCT
fnp-2819	161	12	and	and	CCONJ
fnp-2819	161	13	depicted	depict	VERB
fnp-2819	161	14	as	as	ADP
fnp-2819	161	15	mean	mean	PROPN
fnp-2819	161	16	±	±	NUM
fnp-2819	161	17	sem	sem	NOUN
fnp-2819	161	18	of	of	ADP
fnp-2819	161	19	triplicate	triplicate	NOUN
fnp-2819	161	20	samples	sample	NOUN
fnp-2819	161	21	.	.	PUNCT
fnp-2819	162	1	statistical	statistical	ADJ
fnp-2819	162	2	significance	significance	NOUN
fnp-2819	162	3	(	(	PUNCT
fnp-2819	162	4	p<0.05	p<0.05	NOUN
fnp-2819	162	5	)	)	PUNCT
fnp-2819	162	6	between	between	ADP
fnp-2819	162	7	control	control	NOUN
fnp-2819	162	8	and	and	CCONJ
fnp-2819	162	9	drug	drug	NOUN
fnp-2819	162	10	-	-	PUNCT
fnp-2819	162	11	treated	treat	VERB
fnp-2819	162	12	mice	mouse	NOUN
fnp-2819	162	13	was	be	AUX
fnp-2819	162	14	determined	determine	VERB
fnp-2819	162	15	using	use	VERB
fnp-2819	162	16	an	an	DET
fnp-2819	162	17	unpaired	unpaired	ADJ
fnp-2819	162	18	two	two	NUM
fnp-2819	162	19	-	-	PUNCT
fnp-2819	162	20	tailed	tail	VERB
fnp-2819	162	21	t	t	NOUN
fnp-2819	162	22	-	-	PUNCT
fnp-2819	162	23	test	test	NOUN
fnp-2819	162	24	and	and	CCONJ
fnp-2819	162	25	indicated	indicate	VERB
fnp-2819	162	26	by	by	ADP
fnp-2819	162	27	asterisks	asterisk	NOUN
fnp-2819	162	28	.	.	PUNCT
fnp-2819	163	1	unimmunized	unimmunized	ADJ
fnp-2819	163	2	mice	mouse	NOUN
fnp-2819	163	3	(	(	PUNCT
fnp-2819	163	4	10	10	NUM
fnp-2819	163	5	/	/	SYM
fnp-2819	163	6	group	group	NOUN
fnp-2819	163	7	)	)	PUNCT
fnp-2819	163	8	were	be	AUX
fnp-2819	163	9	treated	treat	VERB
fnp-2819	163	10	with	with	ADP
fnp-2819	163	11	dmso	dmso	NOUN
fnp-2819	163	12	or	or	CCONJ
fnp-2819	163	13	tsa	tsa	NOUN
fnp-2819	163	14	and	and	CCONJ
fnp-2819	163	15	analyzed	analyze	VERB
fnp-2819	163	16	one	one	NUM
fnp-2819	163	17	day	day	NOUN
fnp-2819	163	18	later	later	ADV
fnp-2819	163	19	for	for	SCONJ
fnp-2819	163	20	the	the	DET
fnp-2819	163	21	effect	effect	NOUN
fnp-2819	163	22	of	of	ADP
fnp-2819	163	23	drug	drug	NOUN
fnp-2819	163	24	treatment	treatment	NOUN
fnp-2819	163	25	on	on	ADP
fnp-2819	163	26	the	the	DET
fnp-2819	163	27	basal	basal	ADJ
fnp-2819	163	28	level	level	NOUN
fnp-2819	163	29	expression	expression	NOUN
fnp-2819	163	30	of	of	ADP
fnp-2819	163	31	genes	gene	NOUN
fnp-2819	163	32	irrespective	irrespective	ADV
fnp-2819	163	33	of	of	ADP
fnp-2819	163	34	immunization	immunization	NOUN
fnp-2819	163	35	.	.	PUNCT
fnp-2819	164	1	3.4	3.4	NUM
fnp-2819	164	2	.	.	PUNCT
fnp-2819	164	3	epigenetic	epigenetic	ADJ
fnp-2819	164	4	regulation	regulation	NOUN
fnp-2819	164	5	failed	fail	VERB
fnp-2819	164	6	to	to	PART
fnp-2819	164	7	influence	influence	VERB
fnp-2819	164	8	the	the	DET
fnp-2819	164	9	prominent	prominent	ADJ
fnp-2819	164	10	chemokine	chemokine	ADJ
fnp-2819	164	11	system	system	NOUN
fnp-2819	164	12	since	since	SCONJ
fnp-2819	164	13	previous	previous	ADJ
fnp-2819	164	14	work	work	NOUN
fnp-2819	164	15	indicated	indicate	VERB
fnp-2819	164	16	the	the	DET
fnp-2819	164	17	nonredundant	nonredundant	ADJ
fnp-2819	164	18	roles	role	NOUN
fnp-2819	164	19	of	of	ADP
fnp-2819	164	20	ccl2	ccl2	NOUN
fnp-2819	164	21	and	and	CCONJ
fnp-2819	164	22	ccr2	ccr2	NOUN
fnp-2819	164	23	in	in	ADP
fnp-2819	164	24	recruiting	recruit	VERB
fnp-2819	164	25	the	the	DET
fnp-2819	164	26	inflammatory	inflammatory	ADJ
fnp-2819	164	27	cells	cell	NOUN
fnp-2819	164	28	to	to	ADP
fnp-2819	164	29	the	the	DET
fnp-2819	164	30	cns	cns	PROPN
fnp-2819	164	31	(	(	PUNCT
fnp-2819	164	32	mahad	mahad	PROPN
fnp-2819	164	33	and	and	CCONJ
fnp-2819	164	34	ransohoff	ransohoff	NOUN
fnp-2819	164	35	,	,	PUNCT
fnp-2819	164	36	2003	2003	NUM
fnp-2819	164	37	;	;	PUNCT
fnp-2819	164	38	moreno	moreno	PROPN
fnp-2819	164	39	et	et	PROPN
fnp-2819	164	40	al	al	PROPN
fnp-2819	164	41	.	.	PROPN
fnp-2819	164	42	,	,	PUNCT
fnp-2819	164	43	2014	2014	NUM
fnp-2819	164	44	)	)	PUNCT
fnp-2819	164	45	,	,	PUNCT
fnp-2819	164	46	we	we	PRON
fnp-2819	164	47	surmised	surmise	VERB
fnp-2819	164	48	that	that	SCONJ
fnp-2819	164	49	tsa	tsa	NOUN
fnp-2819	164	50	-	-	PUNCT
fnp-2819	164	51	induced	induce	VERB
fnp-2819	164	52	neuroprotection	neuroprotection	NOUN
fnp-2819	164	53	could	could	AUX
fnp-2819	164	54	also	also	ADV
fnp-2819	164	55	accompany	accompany	VERB
fnp-2819	164	56	modulation	modulation	NOUN
fnp-2819	164	57	of	of	ADP
fnp-2819	164	58	these	these	DET
fnp-2819	164	59	genes	gene	NOUN
fnp-2819	164	60	.	.	PUNCT
fnp-2819	165	1	immunization	immunization	NOUN
fnp-2819	165	2	of	of	ADP
fnp-2819	165	3	nod	nod	NOUN
fnp-2819	165	4	mice	mouse	NOUN
fnp-2819	165	5	with	with	ADP
fnp-2819	165	6	mog35	mog35	NOUN
fnp-2819	165	7	-	-	SYM
fnp-2819	165	8	55	55	NUM
fnp-2819	165	9	did	do	AUX
fnp-2819	165	10	not	not	PART
fnp-2819	165	11	transcriptionally	transcriptionally	ADV
fnp-2819	165	12	upregulate	upregulate	VERB
fnp-2819	165	13	ccl2	ccl2	NOUN
fnp-2819	165	14	in	in	ADP
fnp-2819	165	15	the	the	DET
fnp-2819	165	16	cns	cns	PROPN
fnp-2819	165	17	(	(	PUNCT
fnp-2819	165	18	fig	fig	NOUN
fnp-2819	165	19	.	.	PUNCT
fnp-2819	165	20	4a	4a	NUM
fnp-2819	165	21	)	)	PUNCT
fnp-2819	165	22	.	.	PUNCT
fnp-2819	166	1	on	on	ADP
fnp-2819	166	2	the	the	DET
fnp-2819	166	3	other	other	ADJ
fnp-2819	166	4	hand	hand	NOUN
fnp-2819	166	5	,	,	PUNCT
fnp-2819	166	6	ccl2	ccl2	NOUN
fnp-2819	166	7	transcription	transcription	NOUN
fnp-2819	166	8	increased	increase	VERB
fnp-2819	166	9	dramatically	dramatically	ADV
fnp-2819	166	10	in	in	ADP
fnp-2819	166	11	the	the	DET
fnp-2819	166	12	slo	slo	PROPN
fnp-2819	166	13	between	between	ADP
fnp-2819	166	14	days	day	NOUN
fnp-2819	166	15	14	14	NUM
fnp-2819	166	16	and	and	CCONJ
fnp-2819	166	17	28	28	NUM
fnp-2819	166	18	(	(	PUNCT
fnp-2819	166	19	fig	fig	NOUN
fnp-2819	166	20	.	.	PUNCT
fnp-2819	167	1	4b	4b	PROPN
fnp-2819	167	2	)	)	PUNCT
fnp-2819	167	3	.	.	PUNCT
fnp-2819	168	1	however	however	ADV
fnp-2819	168	2	,	,	PUNCT
fnp-2819	168	3	tsa	tsa	NOUN
fnp-2819	168	4	treatment	treatment	NOUN
fnp-2819	168	5	failed	fail	VERB
fnp-2819	168	6	to	to	PART
fnp-2819	168	7	modulate	modulate	VERB
fnp-2819	168	8	the	the	DET
fnp-2819	168	9	transcription	transcription	NOUN
fnp-2819	168	10	of	of	ADP
fnp-2819	168	11	ccl2	ccl2	NOUN
fnp-2819	168	12	in	in	ADP
fnp-2819	168	13	the	the	DET
fnp-2819	168	14	sc	sc	PROPN
fnp-2819	168	15	or	or	CCONJ
fnp-2819	168	16	slo	slo	PROPN
fnp-2819	168	17	.	.	PUNCT
fnp-2819	169	1	the	the	DET
fnp-2819	169	2	gene	gene	NOUN
fnp-2819	169	3	encoding	encode	VERB
fnp-2819	169	4	the	the	DET
fnp-2819	169	5	cognate	cognate	NOUN
fnp-2819	169	6	receptor	receptor	NOUN
fnp-2819	169	7	of	of	ADP
fnp-2819	169	8	ccl2	ccl2	PROPN
fnp-2819	169	9	,	,	PUNCT
fnp-2819	169	10	ccr2	ccr2	PROPN
fnp-2819	169	11	,	,	PUNCT
fnp-2819	169	12	was	be	AUX
fnp-2819	169	13	not	not	PART
fnp-2819	169	14	distinctively	distinctively	ADV
fnp-2819	169	15	upregulated	upregulate	VERB
fnp-2819	169	16	in	in	ADP
fnp-2819	169	17	either	either	CCONJ
fnp-2819	169	18	the	the	DET
fnp-2819	169	19	sc	sc	PROPN
fnp-2819	169	20	or	or	CCONJ
fnp-2819	169	21	slo	slo	PROPN
fnp-2819	169	22	nor	nor	CCONJ
fnp-2819	169	23	perturbed	perturb	VERB
fnp-2819	169	24	by	by	ADP
fnp-2819	169	25	the	the	DET
fnp-2819	169	26	histone	histone	NOUN
fnp-2819	169	27	modifier	modifier	NOUN
fnp-2819	169	28	(	(	PUNCT
fnp-2819	169	29	fig	fig	NOUN
fnp-2819	169	30	.	.	PUNCT
fnp-2819	170	1	4c	4c	NOUN
fnp-2819	170	2	-	-	PUNCT
fnp-2819	170	3	d	d	NOUN
fnp-2819	170	4	)	)	PUNCT
fnp-2819	170	5	.	.	PUNCT
fnp-2819	171	1	in	in	ADP
fnp-2819	171	2	contrast	contrast	NOUN
fnp-2819	171	3	to	to	ADP
fnp-2819	171	4	the	the	DET
fnp-2819	171	5	robust	robust	ADJ
fnp-2819	171	6	increase	increase	NOUN
fnp-2819	171	7	in	in	ADP
fnp-2819	171	8	the	the	DET
fnp-2819	171	9	ccl2	ccl2	PROPN
fnp-2819	171	10	mrna	mrna	PROPN
fnp-2819	171	11	level	level	NOUN
fnp-2819	171	12	in	in	ADP
fnp-2819	171	13	the	the	DET
fnp-2819	171	14	slo	slo	PROPN
fnp-2819	171	15	,	,	PUNCT
fnp-2819	171	16	the	the	DET
fnp-2819	171	17	amount	amount	NOUN
fnp-2819	171	18	of	of	ADP
fnp-2819	171	19	ccl2	ccl2	NOUN
fnp-2819	171	20	protein	protein	NOUN
fnp-2819	171	21	did	do	AUX
fnp-2819	171	22	not	not	PART
fnp-2819	171	23	increase	increase	VERB
fnp-2819	171	24	in	in	ADP
fnp-2819	171	25	circulation	circulation	NOUN
fnp-2819	171	26	during	during	ADP
fnp-2819	171	27	the	the	DET
fnp-2819	171	28	pre	pre	ADJ
fnp-2819	171	29	-	-	ADJ
fnp-2819	171	30	symptomatic	symptomatic	ADJ
fnp-2819	171	31	period	period	NOUN
fnp-2819	171	32	(	(	PUNCT
fnp-2819	171	33	up	up	ADP
fnp-2819	171	34	to	to	PART
fnp-2819	171	35	16	16	NUM
fnp-2819	171	36	days	day	NOUN
fnp-2819	171	37	)	)	PUNCT
fnp-2819	171	38	as	as	SCONJ
fnp-2819	171	39	assessed	assess	VERB
fnp-2819	171	40	by	by	ADP
fnp-2819	171	41	elisa	elisa	PROPN
fnp-2819	171	42	,	,	PUNCT
fnp-2819	171	43	which	which	PRON
fnp-2819	171	44	remained	remain	VERB
fnp-2819	171	45	unaffected	unaffected	ADJ
fnp-2819	171	46	by	by	ADP
fnp-2819	171	47	tsa	tsa	NOUN
fnp-2819	171	48	treatment	treatment	NOUN
fnp-2819	171	49	(	(	PUNCT
fnp-2819	171	50	fig	fig	NOUN
fnp-2819	171	51	.	.	PUNCT
fnp-2819	172	1	4e	4e	NOUN
fnp-2819	172	2	)	)	PUNCT
fnp-2819	172	3	.	.	PUNCT
fnp-2819	173	1	these	these	DET
fnp-2819	173	2	data	datum	NOUN
fnp-2819	173	3	indicate	indicate	VERB
fnp-2819	173	4	that	that	SCONJ
fnp-2819	173	5	protection	protection	NOUN
fnp-2819	173	6	from	from	ADP
fnp-2819	173	7	peae	peae	PROPN
fnp-2819	173	8	afforded	afford	VERB
fnp-2819	173	9	by	by	ADP
fnp-2819	173	10	the	the	DET
fnp-2819	173	11	cns	cns	NOUN
fnp-2819	173	12	-	-	PUNCT
fnp-2819	173	13	permeant	permeant	ADJ
fnp-2819	173	14	tsa	tsa	NOUN
fnp-2819	173	15	(	(	PUNCT
fnp-2819	173	16	jayaraman	jayaraman	PROPN
fnp-2819	173	17	et	et	PROPN
fnp-2819	173	18	al	al	PROPN
fnp-2819	173	19	.	.	PROPN
fnp-2819	173	20	,	,	PUNCT
fnp-2819	173	21	2017	2017	NUM
fnp-2819	173	22	;	;	PUNCT
fnp-2819	173	23	2018	2018	NUM
fnp-2819	173	24	)	)	PUNCT
fnp-2819	173	25	was	be	AUX
fnp-2819	173	26	not	not	PART
fnp-2819	173	27	associated	associate	VERB
fnp-2819	173	28	with	with	ADP
fnp-2819	173	29	the	the	DET
fnp-2819	173	30	transcriptional	transcriptional	ADJ
fnp-2819	173	31	regulation	regulation	NOUN
fnp-2819	173	32	of	of	ADP
fnp-2819	173	33	the	the	DET
fnp-2819	173	34	prominent	prominent	ADJ
fnp-2819	173	35	chemokine	chemokine	ADJ
fnp-2819	173	36	system	system	NOUN
fnp-2819	173	37	,	,	PUNCT
fnp-2819	173	38	ccl2	ccl2	PROPN
fnp-2819	173	39	:	:	PUNCT
fnp-2819	173	40	ccr2	ccr2	VERB
fnp-2819	173	41	either	either	CCONJ
fnp-2819	173	42	in	in	ADP
fnp-2819	173	43	the	the	DET
fnp-2819	173	44	cns	cns	PROPN
fnp-2819	173	45	or	or	CCONJ
fnp-2819	173	46	slo	slo	PROPN
fnp-2819	173	47	.	.	PROPN
fnp-2819	173	48	fig	fig	PROPN
fnp-2819	173	49	.	.	PUNCT
fnp-2819	174	1	4	4	NUM
fnp-2819	174	2	epigenetic	epigenetic	ADJ
fnp-2819	174	3	regulation	regulation	NOUN
fnp-2819	174	4	failed	fail	VERB
fnp-2819	174	5	to	to	PART
fnp-2819	174	6	influence	influence	VERB
fnp-2819	174	7	the	the	DET
fnp-2819	174	8	prominent	prominent	ADJ
fnp-2819	174	9	chemokine	chemokine	ADJ
fnp-2819	174	10	system	system	NOUN
fnp-2819	174	11	.	.	PUNCT
fnp-2819	174	12	  	  	SPACE
fnp-2819	175	1	expression	expression	NOUN
fnp-2819	175	2	levels	level	NOUN
fnp-2819	175	3	of	of	ADP
fnp-2819	175	4	indicated	indicate	VERB
fnp-2819	175	5	genes	gene	NOUN
fnp-2819	175	6	were	be	AUX
fnp-2819	175	7	determined	determine	VERB
fnp-2819	175	8	in	in	ADP
fnp-2819	175	9	dmso	dmso	NOUN
fnp-2819	175	10	(	(	PUNCT
fnp-2819	175	11	blank	blank	ADJ
fnp-2819	175	12	bars	bar	NOUN
fnp-2819	175	13	)	)	PUNCT
fnp-2819	175	14	and	and	CCONJ
fnp-2819	175	15	tsa	tsa	NOUN
fnp-2819	175	16	-	-	PUNCT
fnp-2819	175	17	treated	treat	VERB
fnp-2819	175	18	mice	mouse	NOUN
fnp-2819	175	19	(	(	PUNCT
fnp-2819	175	20	hatched	hatch	VERB
fnp-2819	175	21	bars	bar	NOUN
fnp-2819	175	22	)	)	PUNCT
fnp-2819	175	23	using	use	VERB
fnp-2819	175	24	the	the	DET
fnp-2819	175	25	total	total	ADJ
fnp-2819	175	26	rna	rna	NOUN
fnp-2819	175	27	derived	derive	VERB
fnp-2819	175	28	from	from	ADP
fnp-2819	175	29	the	the	DET
fnp-2819	175	30	spinal	spinal	ADJ
fnp-2819	175	31	cord	cord	NOUN
fnp-2819	175	32	(	(	PUNCT
fnp-2819	175	33	sc	sc	PROPN
fnp-2819	175	34	)	)	PUNCT
fnp-2819	175	35	(	(	PUNCT
fnp-2819	175	36	a	a	PRON
fnp-2819	175	37	,	,	PUNCT
fnp-2819	175	38	c	c	NOUN
fnp-2819	175	39	)	)	PUNCT
fnp-2819	175	40	and	and	CCONJ
fnp-2819	175	41	peripheral	peripheral	ADJ
fnp-2819	175	42	lymphoid	lymphoid	ADJ
fnp-2819	175	43	tissues	tissue	NOUN
fnp-2819	175	44	(	(	PUNCT
fnp-2819	175	45	sp	sp	NOUN
fnp-2819	175	46	)	)	PUNCT
fnp-2819	175	47	(	(	PUNCT
fnp-2819	175	48	b	b	X
fnp-2819	175	49	,	,	PUNCT
fnp-2819	175	50	d	d	NOUN
fnp-2819	175	51	)	)	PUNCT
fnp-2819	175	52	at	at	ADP
fnp-2819	175	53	various	various	ADJ
fnp-2819	175	54	time	time	NOUN
fnp-2819	175	55	points	point	NOUN
fnp-2819	175	56	.	.	PUNCT
fnp-2819	176	1	at	at	ADP
fnp-2819	176	2	each	each	DET
fnp-2819	176	3	time	time	NOUN
fnp-2819	176	4	point	point	NOUN
fnp-2819	176	5	,	,	PUNCT
fnp-2819	176	6	rna	rna	PROPN
fnp-2819	176	7	was	be	AUX
fnp-2819	176	8	extracted	extract	VERB
fnp-2819	176	9	from	from	ADP
fnp-2819	176	10	five	five	NUM
fnp-2819	176	11	individual	individual	ADJ
fnp-2819	176	12	mice	mouse	NOUN
fnp-2819	176	13	/	/	SYM
fnp-2819	176	14	group	group	NOUN
fnp-2819	176	15	,	,	PUNCT
fnp-2819	176	16	pooled	pool	VERB
fnp-2819	176	17	,	,	PUNCT
fnp-2819	176	18	and	and	CCONJ
fnp-2819	176	19	analyzed	analyze	VERB
fnp-2819	176	20	in	in	ADP
fnp-2819	176	21	triplicate	triplicate	NOUN
fnp-2819	176	22	.	.	PUNCT
fnp-2819	177	1	gene	gene	NOUN
fnp-2819	177	2	expression	expression	NOUN
fnp-2819	177	3	was	be	AUX
fnp-2819	177	4	normalized	normalize	VERB
fnp-2819	177	5	to	to	ADP
fnp-2819	177	6	the	the	DET
fnp-2819	177	7	housekeeping	housekeeping	NOUN
fnp-2819	177	8	gene	gene	NOUN
fnp-2819	177	9	,	,	PUNCT
fnp-2819	177	10	gapdh	gapdh	NOUN
fnp-2819	177	11	,	,	PUNCT
fnp-2819	177	12	and	and	CCONJ
fnp-2819	177	13	depicted	depict	VERB
fnp-2819	177	14	as	as	ADP
fnp-2819	177	15	mean	mean	PROPN
fnp-2819	177	16	±	±	NUM
fnp-2819	177	17	sem	sem	NOUN
fnp-2819	177	18	of	of	ADP
fnp-2819	177	19	triplicate	triplicate	NOUN
fnp-2819	177	20	samples	sample	NOUN
fnp-2819	177	21	.	.	PUNCT
fnp-2819	178	1	individual	individual	ADJ
fnp-2819	178	2	data	datum	NOUN
fnp-2819	178	3	points	point	NOUN
fnp-2819	178	4	are	be	AUX
fnp-2819	178	5	shown	show	VERB
fnp-2819	178	6	for	for	ADP
fnp-2819	178	7	dmso	dmso	NOUN
fnp-2819	178	8	(	(	PUNCT
fnp-2819	178	9	blank	blank	ADJ
fnp-2819	178	10	circles	circle	NOUN
fnp-2819	178	11	)	)	PUNCT
fnp-2819	178	12	and	and	CCONJ
fnp-2819	178	13	tsa	tsa	NOUN
fnp-2819	178	14	-	-	PUNCT
fnp-2819	178	15	treated	treat	VERB
fnp-2819	178	16	(	(	PUNCT
fnp-2819	178	17	empty	empty	ADJ
fnp-2819	178	18	squares	square	NOUN
fnp-2819	178	19	)	)	PUNCT
fnp-2819	178	20	groups	group	NOUN
fnp-2819	178	21	.	.	PUNCT
fnp-2819	179	1	ccl2	ccl2	NOUN
fnp-2819	179	2	protein	protein	NOUN
fnp-2819	179	3	was	be	AUX
fnp-2819	179	4	estimated	estimate	VERB
fnp-2819	179	5	in	in	ADP
fnp-2819	179	6	duplicate	duplicate	NOUN
fnp-2819	179	7	from	from	ADP
fnp-2819	179	8	pooled	pool	VERB
fnp-2819	179	9	sera	sera	NOUN
fnp-2819	179	10	of	of	ADP
fnp-2819	179	11	five	five	NUM
fnp-2819	179	12	mice	mouse	NOUN
fnp-2819	179	13	per	per	ADP
fnp-2819	179	14	group	group	NOUN
fnp-2819	179	15	using	use	VERB
fnp-2819	179	16	elisa	elisa	PROPN
fnp-2819	179	17	(	(	PUNCT
fnp-2819	179	18	e	e	NOUN
fnp-2819	179	19	)	)	PUNCT
fnp-2819	179	20	.	.	PUNCT
fnp-2819	180	1	unimmunized	unimmunized	ADJ
fnp-2819	180	2	mice	mouse	NOUN
fnp-2819	180	3	(	(	PUNCT
fnp-2819	180	4	10	10	NUM
fnp-2819	180	5	/	/	SYM
fnp-2819	180	6	group	group	NOUN
fnp-2819	180	7	)	)	PUNCT
fnp-2819	180	8	were	be	AUX
fnp-2819	180	9	treated	treat	VERB
fnp-2819	180	10	with	with	ADP
fnp-2819	180	11	dmso	dmso	NOUN
fnp-2819	180	12	or	or	CCONJ
fnp-2819	180	13	tsa	tsa	NOUN
fnp-2819	180	14	and	and	CCONJ
fnp-2819	180	15	analyzed	analyze	VERB
fnp-2819	180	16	one	one	NUM
fnp-2819	180	17	day	day	NOUN
fnp-2819	180	18	later	later	ADV
fnp-2819	180	19	for	for	SCONJ
fnp-2819	180	20	the	the	DET
fnp-2819	180	21	effect	effect	NOUN
fnp-2819	180	22	of	of	ADP
fnp-2819	180	23	drug	drug	NOUN
fnp-2819	180	24	treatment	treatment	NOUN
fnp-2819	180	25	on	on	ADP
fnp-2819	180	26	the	the	DET
fnp-2819	180	27	basal	basal	ADJ
fnp-2819	180	28	level	level	NOUN
fnp-2819	180	29	expression	expression	NOUN
fnp-2819	180	30	of	of	ADP
fnp-2819	180	31	genes	gene	NOUN
fnp-2819	180	32	irrespective	irrespective	ADV
fnp-2819	180	33	of	of	ADP
fnp-2819	180	34	immunization	immunization	NOUN
fnp-2819	180	35	.	.	PUNCT
fnp-2819	181	1	statistical	statistical	ADJ
fnp-2819	181	2	significance	significance	NOUN
fnp-2819	181	3	(	(	PUNCT
fnp-2819	181	4	p<0.05	p<0.05	NOUN
fnp-2819	181	5	)	)	PUNCT
fnp-2819	181	6	between	between	ADP
fnp-2819	181	7	control	control	NOUN
fnp-2819	181	8	and	and	CCONJ
fnp-2819	181	9	drug	drug	NOUN
fnp-2819	181	10	-	-	PUNCT
fnp-2819	181	11	treated	treat	VERB
fnp-2819	181	12	mice	mouse	NOUN
fnp-2819	181	13	(	(	PUNCT
fnp-2819	181	14	n	n	CCONJ
fnp-2819	181	15	=	=	SYM
fnp-2819	181	16	five	five	NUM
fnp-2819	181	17	/	/	SYM
fnp-2819	181	18	group	group	NOUN
fnp-2819	181	19	)	)	PUNCT
fnp-2819	181	20	was	be	AUX
fnp-2819	181	21	determined	determine	VERB
fnp-2819	181	22	using	use	VERB
fnp-2819	181	23	an	an	DET
fnp-2819	181	24	unpaired	unpaired	ADJ
fnp-2819	181	25	two	two	NUM
fnp-2819	181	26	-	-	PUNCT
fnp-2819	181	27	tailed	tail	VERB
fnp-2819	181	28	t	t	NOUN
fnp-2819	181	29	-	-	PUNCT
fnp-2819	181	30	test	test	NOUN
fnp-2819	181	31	and	and	CCONJ
fnp-2819	181	32	indicated	indicate	VERB
fnp-2819	181	33	by	by	ADP
fnp-2819	181	34	asterisks	asterisk	NOUN
fnp-2819	181	35	.	.	PUNCT
fnp-2819	182	1	3.5	3.5	NUM
fnp-2819	182	2	.	.	PUNCT
fnp-2819	182	3	tsa	tsa	NOUN
fnp-2819	182	4	treatment	treatment	NOUN
fnp-2819	182	5	repressed	repress	VERB
fnp-2819	182	6	the	the	DET
fnp-2819	182	7	transcription	transcription	NOUN
fnp-2819	182	8	of	of	ADP
fnp-2819	182	9	hdac11	hdac11	NOUN
fnp-2819	182	10	selectively	selectively	ADV
fnp-2819	182	11	in	in	ADP
fnp-2819	182	12	the	the	DET
fnp-2819	182	13	cns	cns	NOUN
fnp-2819	182	14	whereas	whereas	SCONJ
fnp-2819	182	15	tsa	tsa	NOUN
fnp-2819	182	16	can	can	AUX
fnp-2819	182	17	inhibit	inhibit	VERB
fnp-2819	182	18	the	the	DET
fnp-2819	182	19	activity	activity	NOUN
fnp-2819	182	20	of	of	ADP
fnp-2819	182	21	hdac	hdac	PROPN
fnp-2819	182	22	class	class	PROPN
fnp-2819	183	1	i	i	PROPN
fnp-2819	183	2	,	,	PUNCT
fnp-2819	183	3	iia	iia	PROPN
fnp-2819	183	4	,	,	PUNCT
fnp-2819	183	5	and	and	CCONJ
fnp-2819	183	6	iib	iib	NOUN
fnp-2819	183	7	isoenzymes	isoenzyme	VERB
fnp-2819	183	8	with	with	ADP
fnp-2819	183	9	varying	vary	VERB
fnp-2819	183	10	potency	potency	NOUN
fnp-2819	183	11	in	in	ADP
fnp-2819	183	12	vitro	vitro	X
fnp-2819	183	13	(	(	PUNCT
fnp-2819	183	14	bradner	bradner	NOUN
fnp-2819	183	15	et	et	PROPN
fnp-2819	183	16	al	al	PROPN
fnp-2819	183	17	.	.	PROPN
fnp-2819	183	18	,	,	PUNCT
fnp-2819	183	19	2010	2010	NUM
fnp-2819	183	20	)	)	PUNCT
fnp-2819	183	21	,	,	PUNCT
fnp-2819	183	22	its	its	PRON
fnp-2819	183	23	ability	ability	NOUN
fnp-2819	183	24	to	to	PART
fnp-2819	183	25	regulate	regulate	VERB
fnp-2819	183	26	hdac	hdac	NOUN
fnp-2819	183	27	genes	gene	NOUN
fnp-2819	183	28	in	in	ADP
fnp-2819	183	29	vivo	vivo	NOUN
fnp-2819	183	30	has	have	AUX
fnp-2819	183	31	not	not	PART
fnp-2819	183	32	been	be	AUX
fnp-2819	183	33	determined	determine	VERB
fnp-2819	183	34	.	.	PUNCT
fnp-2819	184	1	to	to	PART
fnp-2819	184	2	address	address	VERB
fnp-2819	184	3	this	this	DET
fnp-2819	184	4	issue	issue	NOUN
fnp-2819	184	5	,	,	PUNCT
fnp-2819	184	6	we	we	PRON
fnp-2819	184	7	analyzed	analyze	VERB
fnp-2819	184	8	the	the	DET
fnp-2819	184	9	mrna	mrna	PROPN
fnp-2819	184	10	levels	level	NOUN
fnp-2819	184	11	of	of	ADP
fnp-2819	184	12	class	class	NOUN
fnp-2819	184	13	i	i	PROPN
fnp-2819	184	14	(	(	PUNCT
fnp-2819	184	15	hdac1	hdac1	NOUN
fnp-2819	184	16	,	,	PUNCT
fnp-2819	184	17	hdac2	hdac2	NOUN
fnp-2819	184	18	,	,	PUNCT
fnp-2819	184	19	hdac3	hdac3	NOUN
fnp-2819	184	20	,	,	PUNCT
fnp-2819	184	21	and	and	CCONJ
fnp-2819	184	22	hdac8	hdac8	NOUN
fnp-2819	184	23	)	)	PUNCT
fnp-2819	184	24	,	,	PUNCT
fnp-2819	184	25	class	class	NOUN
fnp-2819	184	26	iia	iia	NOUN
fnp-2819	184	27	(	(	PUNCT
fnp-2819	184	28	hdac4	hdac4	PROPN
fnp-2819	184	29	,	,	PUNCT
fnp-2819	184	30	hdac5	hdac5	PROPN
fnp-2819	184	31	,	,	PUNCT
fnp-2819	184	32	hdac7	hdac7	X
fnp-2819	184	33	,	,	PUNCT
fnp-2819	184	34	and	and	CCONJ
fnp-2819	184	35	hdac9	hdac9	NOUN
fnp-2819	184	36	)	)	PUNCT
fnp-2819	184	37	,	,	PUNCT
fnp-2819	184	38	class	class	NOUN
fnp-2819	184	39	iib	iib	NOUN
fnp-2819	184	40	(	(	PUNCT
fnp-2819	184	41	hdac6	hdac6	PROPN
fnp-2819	184	42	and	and	CCONJ
fnp-2819	184	43	hdac10	hdac10	PROPN
fnp-2819	184	44	)	)	PUNCT
fnp-2819	184	45	,	,	PUNCT
fnp-2819	184	46	and	and	CCONJ
fnp-2819	184	47	class	class	NOUN
fnp-2819	184	48	iv	iv	NUM
fnp-2819	184	49	(	(	PUNCT
fnp-2819	184	50	hdac11	hdac11	NOUN
fnp-2819	184	51	)	)	PUNCT
fnp-2819	184	52	hdacs	hdac	NOUN
fnp-2819	184	53	using	use	VERB
fnp-2819	184	54	validated	validated	ADJ
fnp-2819	184	55	primer	primer	NOUN
fnp-2819	184	56	sets	set	NOUN
fnp-2819	184	57	and	and	CCONJ
fnp-2819	184	58	qrt	qrt	NOUN
fnp-2819	184	59	-	-	PUNCT
fnp-2819	184	60	pcr	pcr	NOUN
fnp-2819	184	61	.	.	PUNCT
fnp-2819	185	1	data	datum	NOUN
fnp-2819	185	2	shown	show	VERB
fnp-2819	185	3	in	in	ADP
fnp-2819	185	4	fig	fig	NOUN
fnp-2819	185	5	.	.	PUNCT
fnp-2819	186	1	5	5	NUM
fnp-2819	186	2	indicate	indicate	VERB
fnp-2819	186	3	that	that	SCONJ
fnp-2819	186	4	immunization	immunization	NOUN
fnp-2819	186	5	of	of	ADP
fnp-2819	186	6	nod	nod	NOUN
fnp-2819	186	7	mice	mouse	NOUN
fnp-2819	186	8	with	with	ADP
fnp-2819	186	9	mog35	mog35	NOUN
fnp-2819	186	10	-	-	PUNCT
fnp-2819	186	11	55	55	NUM
fnp-2819	186	12	steadily	steadily	ADV
fnp-2819	186	13	increased	increase	VERB
fnp-2819	186	14	the	the	DET
fnp-2819	186	15	transcription	transcription	NOUN
fnp-2819	186	16	of	of	ADP
fnp-2819	186	17	the	the	DET
fnp-2819	186	18	class	class	NOUN
fnp-2819	186	19	iv	iv	NUM
fnp-2819	186	20	hdac11	hdac11	NOUN
fnp-2819	186	21	in	in	ADP
fnp-2819	186	22	the	the	DET
fnp-2819	186	23	sc	sc	PROPN
fnp-2819	186	24	,	,	PUNCT
fnp-2819	186	25	which	which	PRON
fnp-2819	186	26	remained	remain	VERB
fnp-2819	186	27	at	at	ADP
fnp-2819	186	28	high	high	ADJ
fnp-2819	186	29	levels	level	NOUN
fnp-2819	186	30	between	between	ADP
fnp-2819	186	31	21	21	NUM
fnp-2819	186	32	and	and	CCONJ
fnp-2819	186	33	54	54	NUM
fnp-2819	186	34	days	day	NOUN
fnp-2819	186	35	postimmunization	postimmunization	NOUN
fnp-2819	186	36	.	.	PUNCT
fnp-2819	187	1	importantly	importantly	ADV
fnp-2819	187	2	,	,	PUNCT
fnp-2819	187	3	tsa	tsa	NOUN
fnp-2819	187	4	treatment	treatment	NOUN
fnp-2819	187	5	reduced	reduce	VERB
fnp-2819	187	6	the	the	DET
fnp-2819	187	7	transcript	transcript	NOUN
fnp-2819	187	8	level	level	NOUN
fnp-2819	187	9	of	of	ADP
fnp-2819	187	10	hdac11	hdac11	NOUN
fnp-2819	187	11	.	.	PUNCT
fnp-2819	188	1	although	although	SCONJ
fnp-2819	188	2	hdac1	hdac1	NOUN
fnp-2819	188	3	,	,	PUNCT
fnp-2819	188	4	hdac4	hdac4	PROPN
fnp-2819	188	5	,	,	PUNCT
fnp-2819	188	6	hdac5	hdac5	PROPN
fnp-2819	188	7	,	,	PUNCT
fnp-2819	188	8	hdac6	hdac6	PROPN
fnp-2819	188	9	,	,	PUNCT
fnp-2819	188	10	hdac8	hdac8	NOUN
fnp-2819	188	11	,	,	PUNCT
fnp-2819	188	12	and	and	CCONJ
fnp-2819	188	13	hdac9	hdac9	NOUN
fnp-2819	188	14	were	be	AUX
fnp-2819	188	15	modestly	modestly	ADV
fnp-2819	188	16	increased	increase	VERB
fnp-2819	188	17	in	in	ADP
fnp-2819	188	18	the	the	DET
fnp-2819	188	19	cns	cns	NOUN
fnp-2819	188	20	with	with	ADP
fnp-2819	188	21	different	different	ADJ
fnp-2819	188	22	kinetics	kinetic	NOUN
fnp-2819	188	23	after	after	ADP
fnp-2819	188	24	immunization	immunization	NOUN
fnp-2819	188	25	,	,	PUNCT
fnp-2819	188	26	they	they	PRON
fnp-2819	188	27	were	be	AUX
fnp-2819	188	28	relatively	relatively	ADV
fnp-2819	188	29	insensitive	insensitive	ADJ
fnp-2819	188	30	to	to	ADP
fnp-2819	188	31	tsa	tsa	NOUN
fnp-2819	188	32	treatment	treatment	NOUN
fnp-2819	188	33	.	.	PUNCT
fnp-2819	189	1	surprisingly	surprisingly	ADV
fnp-2819	189	2	,	,	PUNCT
fnp-2819	189	3	the	the	DET
fnp-2819	189	4	expression	expression	NOUN
fnp-2819	189	5	levels	level	NOUN
fnp-2819	189	6	of	of	ADP
fnp-2819	189	7	hdac	hdac	NOUN
fnp-2819	189	8	genes	gene	NOUN
fnp-2819	189	9	,	,	PUNCT
fnp-2819	189	10	including	include	VERB
fnp-2819	189	11	the	the	DET
fnp-2819	189	12	hdac11	hdac11	NOUN
fnp-2819	189	13	,	,	PUNCT
fnp-2819	189	14	did	do	AUX
fnp-2819	189	15	not	not	PART
fnp-2819	189	16	increase	increase	VERB
fnp-2819	189	17	significantly	significantly	ADV
fnp-2819	189	18	in	in	ADP
fnp-2819	189	19	the	the	DET
fnp-2819	189	20	slo	slo	PROPN
fnp-2819	189	21	of	of	ADP
fnp-2819	189	22	mog35	mog35	PROPN
fnp-2819	189	23	-	-	PUNCT
fnp-2819	189	24	55	55	NUM
fnp-2819	189	25	immunized	immunize	VERB
fnp-2819	189	26	mice	mouse	NOUN
fnp-2819	189	27	nor	nor	CCONJ
fnp-2819	189	28	repressed	repress	VERB
fnp-2819	189	29	by	by	ADP
fnp-2819	189	30	tsa	tsa	NOUN
fnp-2819	189	31	treatment	treatment	NOUN
fnp-2819	189	32	(	(	PUNCT
fnp-2819	189	33	supplementary	supplementary	ADJ
fnp-2819	189	34	fig	fig	NOUN
fnp-2819	189	35	.	.	PUNCT
fnp-2819	190	1	5	5	NUM
fnp-2819	190	2	)	)	PUNCT
fnp-2819	190	3	.	.	PUNCT
fnp-2819	191	1	these	these	DET
fnp-2819	191	2	results	result	NOUN
fnp-2819	191	3	indicate	indicate	VERB
fnp-2819	191	4	that	that	SCONJ
fnp-2819	191	5	mog35	mog35	NOUN
fnp-2819	191	6	-	-	PUNCT
fnp-2819	191	7	55	55	NUM
fnp-2819	191	8	immunization	immunization	NOUN
fnp-2819	191	9	leads	lead	VERB
fnp-2819	191	10	to	to	ADP
fnp-2819	191	11	increased	increase	VERB
fnp-2819	191	12	transcription	transcription	NOUN
fnp-2819	191	13	of	of	ADP
fnp-2819	191	14	hdac11	hdac11	NOUN
fnp-2819	191	15	in	in	ADP
fnp-2819	191	16	a	a	DET
fnp-2819	191	17	cns	cns	NOUN
fnp-2819	191	18	-	-	PUNCT
fnp-2819	191	19	specific	specific	ADJ
fnp-2819	191	20	fashion	fashion	NOUN
fnp-2819	191	21	,	,	PUNCT
fnp-2819	191	22	which	which	PRON
fnp-2819	191	23	is	be	AUX
fnp-2819	191	24	rendered	render	VERB
fnp-2819	191	25	sensitive	sensitive	ADJ
fnp-2819	191	26	to	to	ADP
fnp-2819	191	27	the	the	DET
fnp-2819	191	28	action	action	NOUN
fnp-2819	191	29	of	of	ADP
fnp-2819	191	30	the	the	DET
fnp-2819	191	31	histone	histone	NOUN
fnp-2819	191	32	modifier	modifier	NOUN
fnp-2819	191	33	.	.	PUNCT
fnp-2819	192	1	these	these	DET
fnp-2819	192	2	results	result	NOUN
fnp-2819	192	3	indicate	indicate	VERB
fnp-2819	192	4	the	the	DET
fnp-2819	192	5	possibility	possibility	NOUN
fnp-2819	192	6	that	that	DET
fnp-2819	192	7	hdac11	hdac11	NOUN
fnp-2819	192	8	could	could	AUX
fnp-2819	192	9	represent	represent	VERB
fnp-2819	192	10	a	a	DET
fnp-2819	192	11	novel	novel	ADJ
fnp-2819	192	12	target	target	NOUN
fnp-2819	192	13	for	for	ADP
fnp-2819	192	14	the	the	DET
fnp-2819	192	15	manipulation	manipulation	NOUN
fnp-2819	192	16	of	of	ADP
fnp-2819	192	17	peae	peae	PROPN
fnp-2819	192	18	.	.	PUNCT
fnp-2819	193	1	fig	fig	NOUN
fnp-2819	193	2	.	.	PUNCT
fnp-2819	194	1	5	5	NUM
fnp-2819	194	2	tsa	tsa	NOUN
fnp-2819	194	3	treatment	treatment	NOUN
fnp-2819	194	4	repressed	repress	VERB
fnp-2819	194	5	the	the	DET
fnp-2819	194	6	transcription	transcription	NOUN
fnp-2819	194	7	of	of	ADP
fnp-2819	194	8	hdac11	hdac11	NOUN
fnp-2819	194	9	selectively	selectively	ADV
fnp-2819	194	10	in	in	ADP
fnp-2819	194	11	the	the	DET
fnp-2819	194	12	cns	cns	NOUN
fnp-2819	194	13	.	.	PUNCT
fnp-2819	194	14	  	  	SPACE
fnp-2819	194	15	expression	expression	NOUN
fnp-2819	194	16	levels	level	NOUN
fnp-2819	194	17	of	of	ADP
fnp-2819	194	18	indicated	indicate	VERB
fnp-2819	194	19	hdac	hdac	NOUN
fnp-2819	194	20	genes	gene	NOUN
fnp-2819	194	21	were	be	AUX
fnp-2819	194	22	determined	determine	VERB
fnp-2819	194	23	in	in	ADP
fnp-2819	194	24	dmso	dmso	NOUN
fnp-2819	194	25	(	(	PUNCT
fnp-2819	194	26	blank	blank	ADJ
fnp-2819	194	27	bars	bar	NOUN
fnp-2819	194	28	)	)	PUNCT
fnp-2819	194	29	and	and	CCONJ
fnp-2819	194	30	tsa	tsa	NOUN
fnp-2819	194	31	-	-	PUNCT
fnp-2819	194	32	treated	treat	VERB
fnp-2819	194	33	mice	mouse	NOUN
fnp-2819	194	34	(	(	PUNCT
fnp-2819	194	35	hatched	hatch	VERB
fnp-2819	194	36	bars	bar	NOUN
fnp-2819	194	37	)	)	PUNCT
fnp-2819	194	38	in	in	ADP
fnp-2819	194	39	the	the	DET
fnp-2819	194	40	spinal	spinal	ADJ
fnp-2819	194	41	cord	cord	NOUN
fnp-2819	194	42	as	as	SCONJ
fnp-2819	194	43	shown	show	VERB
fnp-2819	194	44	.	.	PUNCT
fnp-2819	195	1	at	at	ADP
fnp-2819	195	2	each	each	DET
fnp-2819	195	3	time	time	NOUN
fnp-2819	195	4	point	point	NOUN
fnp-2819	195	5	,	,	PUNCT
fnp-2819	195	6	rna	rna	PROPN
fnp-2819	195	7	was	be	AUX
fnp-2819	195	8	isolated	isolate	VERB
fnp-2819	195	9	from	from	ADP
fnp-2819	195	10	five	five	NUM
fnp-2819	195	11	individual	individual	ADJ
fnp-2819	195	12	mice	mouse	NOUN
fnp-2819	195	13	/	/	SYM
fnp-2819	195	14	group	group	NOUN
fnp-2819	195	15	,	,	PUNCT
fnp-2819	195	16	pooled	pool	VERB
fnp-2819	195	17	and	and	CCONJ
fnp-2819	195	18	analyzed	analyze	VERB
fnp-2819	195	19	in	in	ADP
fnp-2819	195	20	triplicate	triplicate	NOUN
fnp-2819	195	21	.	.	PUNCT
fnp-2819	196	1	gene	gene	NOUN
fnp-2819	196	2	expression	expression	NOUN
fnp-2819	196	3	was	be	AUX
fnp-2819	196	4	normalized	normalize	VERB
fnp-2819	196	5	to	to	ADP
fnp-2819	196	6	the	the	DET
fnp-2819	196	7	housekeeping	housekeeping	NOUN
fnp-2819	196	8	gene	gene	NOUN
fnp-2819	196	9	gapdh	gapdh	NOUN
fnp-2819	196	10	and	and	CCONJ
fnp-2819	196	11	depicted	depict	VERB
fnp-2819	196	12	as	as	ADP
fnp-2819	196	13	mean	mean	PROPN
fnp-2819	196	14	±	±	NUM
fnp-2819	196	15	sem	sem	NOUN
fnp-2819	196	16	of	of	ADP
fnp-2819	196	17	triplicate	triplicate	NOUN
fnp-2819	196	18	samples	sample	NOUN
fnp-2819	196	19	.	.	PUNCT
fnp-2819	197	1	individual	individual	ADJ
fnp-2819	197	2	data	datum	NOUN
fnp-2819	197	3	points	point	NOUN
fnp-2819	197	4	are	be	AUX
fnp-2819	197	5	shown	show	VERB
fnp-2819	197	6	for	for	ADP
fnp-2819	197	7	dmso	dmso	NOUN
fnp-2819	197	8	(	(	PUNCT
fnp-2819	197	9	blank	blank	ADJ
fnp-2819	197	10	circles	circle	NOUN
fnp-2819	197	11	)	)	PUNCT
fnp-2819	197	12	and	and	CCONJ
fnp-2819	197	13	tsa	tsa	NOUN
fnp-2819	197	14	-	-	PUNCT
fnp-2819	197	15	treated	treat	VERB
fnp-2819	197	16	(	(	PUNCT
fnp-2819	197	17	empty	empty	ADJ
fnp-2819	197	18	squares	square	NOUN
fnp-2819	197	19	)	)	PUNCT
fnp-2819	197	20	groups	group	NOUN
fnp-2819	197	21	.	.	PUNCT
fnp-2819	198	1	statistical	statistical	ADJ
fnp-2819	198	2	significance	significance	NOUN
fnp-2819	198	3	(	(	PUNCT
fnp-2819	198	4	p<0.05	p<0.05	NOUN
fnp-2819	198	5	)	)	PUNCT
fnp-2819	198	6	between	between	ADP
fnp-2819	198	7	control	control	NOUN
fnp-2819	198	8	and	and	CCONJ
fnp-2819	198	9	the	the	DET
fnp-2819	198	10	drug	drug	NOUN
fnp-2819	198	11	-	-	PUNCT
fnp-2819	198	12	treated	treat	VERB
fnp-2819	198	13	group	group	NOUN
fnp-2819	198	14	was	be	AUX
fnp-2819	198	15	determined	determine	VERB
fnp-2819	198	16	using	use	VERB
fnp-2819	198	17	an	an	DET
fnp-2819	198	18	unpaired	unpaired	ADJ
fnp-2819	198	19	two	two	NUM
fnp-2819	198	20	-	-	PUNCT
fnp-2819	198	21	tailed	tail	VERB
fnp-2819	198	22	t	t	NOUN
fnp-2819	198	23	-	-	PUNCT
fnp-2819	198	24	test	test	NOUN
fnp-2819	198	25	and	and	CCONJ
fnp-2819	198	26	indicated	indicate	VERB
fnp-2819	198	27	by	by	ADP
fnp-2819	198	28	asterisks	asterisk	NOUN
fnp-2819	198	29	.	.	PUNCT
fnp-2819	199	1	ns	n	VERB
fnp-2819	199	2	,	,	PUNCT
fnp-2819	199	3	not	not	PART
fnp-2819	199	4	significant	significant	ADJ
fnp-2819	199	5	.	.	PUNCT
fnp-2819	200	1	unimmunized	unimmunized	ADJ
fnp-2819	200	2	mice	mouse	NOUN
fnp-2819	200	3	(	(	PUNCT
fnp-2819	200	4	10	10	NUM
fnp-2819	200	5	/	/	SYM
fnp-2819	200	6	group	group	NOUN
fnp-2819	200	7	)	)	PUNCT
fnp-2819	200	8	were	be	AUX
fnp-2819	200	9	treated	treat	VERB
fnp-2819	200	10	with	with	ADP
fnp-2819	200	11	dmso	dmso	NOUN
fnp-2819	200	12	or	or	CCONJ
fnp-2819	200	13	tsa	tsa	NOUN
fnp-2819	200	14	and	and	CCONJ
fnp-2819	200	15	analyzed	analyze	VERB
fnp-2819	200	16	one	one	NUM
fnp-2819	200	17	day	day	NOUN
fnp-2819	200	18	later	later	ADV
fnp-2819	200	19	for	for	SCONJ
fnp-2819	200	20	the	the	DET
fnp-2819	200	21	effect	effect	NOUN
fnp-2819	200	22	of	of	ADP
fnp-2819	200	23	drug	drug	NOUN
fnp-2819	200	24	treatment	treatment	NOUN
fnp-2819	200	25	on	on	ADP
fnp-2819	200	26	the	the	DET
fnp-2819	200	27	basal	basal	ADJ
fnp-2819	200	28	level	level	NOUN
fnp-2819	200	29	expression	expression	NOUN
fnp-2819	200	30	of	of	ADP
fnp-2819	200	31	genes	gene	NOUN
fnp-2819	200	32	irrespective	irrespective	ADV
fnp-2819	200	33	of	of	ADP
fnp-2819	200	34	immunization	immunization	NOUN
fnp-2819	200	35	.	.	PUNCT
fnp-2819	201	1	4	4	X
fnp-2819	201	2	.	.	X
fnp-2819	201	3	discussion	discussion	NOUN
fnp-2819	201	4	a	a	DET
fnp-2819	201	5	cardinal	cardinal	ADJ
fnp-2819	201	6	assumption	assumption	NOUN
fnp-2819	201	7	has	have	AUX
fnp-2819	201	8	been	be	AUX
fnp-2819	201	9	that	that	SCONJ
fnp-2819	201	10	the	the	DET
fnp-2819	201	11	t	t	NOUN
fnp-2819	201	12	lymphocytes	lymphocyte	NOUN
fnp-2819	201	13	play	play	VERB
fnp-2819	201	14	a	a	DET
fnp-2819	201	15	crucial	crucial	ADJ
fnp-2819	201	16	role	role	NOUN
fnp-2819	201	17	in	in	ADP
fnp-2819	201	18	the	the	DET
fnp-2819	201	19	induction	induction	NOUN
fnp-2819	201	20	and	and	CCONJ
fnp-2819	201	21	manifestation	manifestation	NOUN
fnp-2819	201	22	of	of	ADP
fnp-2819	201	23	multiple	multiple	ADJ
fnp-2819	201	24	sclerosis	sclerosis	NOUN
fnp-2819	201	25	,	,	PUNCT
fnp-2819	201	26	and	and	CCONJ
fnp-2819	201	27	therefore	therefore	ADV
fnp-2819	201	28	,	,	PUNCT
fnp-2819	201	29	induction	induction	NOUN
fnp-2819	201	30	of	of	ADP
fnp-2819	201	31	antigen	antigen	NOUN
fnp-2819	201	32	-	-	PUNCT
fnp-2819	201	33	specific	specific	ADJ
fnp-2819	201	34	t	t	NOUN
fnp-2819	201	35	cell	cell	NOUN
fnp-2819	201	36	tolerance	tolerance	NOUN
fnp-2819	201	37	is	be	AUX
fnp-2819	201	38	a	a	DET
fnp-2819	201	39	reasonable	reasonable	ADJ
fnp-2819	201	40	approach	approach	NOUN
fnp-2819	201	41	to	to	PART
fnp-2819	201	42	treat	treat	VERB
fnp-2819	201	43	this	this	DET
fnp-2819	201	44	debilitating	debilitate	VERB
fnp-2819	201	45	disease	disease	NOUN
fnp-2819	201	46	.	.	PUNCT
fnp-2819	202	1	many	many	ADJ
fnp-2819	202	2	attempts	attempt	NOUN
fnp-2819	202	3	,	,	PUNCT
fnp-2819	202	4	including	include	VERB
fnp-2819	202	5	immunization	immunization	NOUN
fnp-2819	202	6	with	with	ADP
fnp-2819	202	7	various	various	ADJ
fnp-2819	202	8	neuronal	neuronal	ADJ
fnp-2819	202	9	peptides	peptide	NOUN
fnp-2819	202	10	and	and	CCONJ
fnp-2819	202	11	t	t	NOUN
fnp-2819	202	12	cell	cell	NOUN
fnp-2819	202	13	vaccinations	vaccination	NOUN
fnp-2819	202	14	,	,	PUNCT
fnp-2819	202	15	have	have	AUX
fnp-2819	202	16	failed	fail	VERB
fnp-2819	202	17	to	to	PART
fnp-2819	202	18	induce	induce	VERB
fnp-2819	202	19	t	t	NOUN
fnp-2819	202	20	cell	cell	NOUN
fnp-2819	202	21	tolerance	tolerance	NOUN
fnp-2819	202	22	and	and	CCONJ
fnp-2819	202	23	ameliorate	ameliorate	VERB
fnp-2819	202	24	multiple	multiple	ADJ
fnp-2819	202	25	sclerosis	sclerosis	NOUN
fnp-2819	202	26	symptoms	symptom	NOUN
fnp-2819	202	27	(	(	PUNCT
fnp-2819	202	28	wingerchuk	wingerchuk	NOUN
fnp-2819	202	29	and	and	CCONJ
fnp-2819	202	30	carter	carter	PROPN
fnp-2819	202	31	,	,	PUNCT
fnp-2819	202	32	2014	2014	NUM
fnp-2819	202	33	;	;	PUNCT
fnp-2819	202	34	dendrou	dendrou	PROPN
fnp-2819	202	35	et	et	PROPN
fnp-2819	202	36	al	al	PROPN
fnp-2819	202	37	.	.	PROPN
fnp-2819	202	38	,	,	PUNCT
fnp-2819	202	39	2015	2015	NUM
fnp-2819	202	40	;	;	PUNCT
fnp-2819	202	41	steinman	steinman	NOUN
fnp-2819	202	42	,	,	PUNCT
fnp-2819	202	43	2015	2015	NUM
fnp-2819	202	44	;	;	PUNCT
fnp-2819	202	45	lassmann	lassmann	PROPN
fnp-2819	202	46	,	,	PUNCT
fnp-2819	202	47	2017	2017	NUM
fnp-2819	202	48	)	)	PUNCT
fnp-2819	202	49	.	.	PUNCT
fnp-2819	203	1	however	however	ADV
fnp-2819	203	2	,	,	PUNCT
fnp-2819	203	3	the	the	DET
fnp-2819	203	4	induction	induction	NOUN
fnp-2819	203	5	of	of	ADP
fnp-2819	203	6	antigen	antigen	NOUN
fnp-2819	203	7	-	-	PUNCT
fnp-2819	203	8	specific	specific	ADJ
fnp-2819	203	9	t	t	NOUN
fnp-2819	203	10	cell	cell	NOUN
fnp-2819	203	11	tolerance	tolerance	NOUN
fnp-2819	203	12	using	use	VERB
fnp-2819	203	13	immunomodulatory	immunomodulatory	ADJ
fnp-2819	203	14	drugs	drug	NOUN
fnp-2819	203	15	remains	remain	VERB
fnp-2819	203	16	unexplored	unexplored	ADJ
fnp-2819	203	17	in	in	ADP
fnp-2819	203	18	patients	patient	NOUN
fnp-2819	203	19	with	with	ADP
fnp-2819	203	20	ms	ms	PROPN
fnp-2819	203	21	and	and	CCONJ
fnp-2819	203	22	other	other	ADJ
fnp-2819	203	23	autoimmune	autoimmune	ADJ
fnp-2819	203	24	disorders	disorder	NOUN
fnp-2819	203	25	.	.	PUNCT
fnp-2819	204	1	recently	recently	ADV
fnp-2819	204	2	,	,	PUNCT
fnp-2819	204	3	we	we	PRON
fnp-2819	204	4	have	have	AUX
fnp-2819	204	5	demonstrated	demonstrate	VERB
fnp-2819	204	6	that	that	SCONJ
fnp-2819	204	7	treatment	treatment	NOUN
fnp-2819	204	8	with	with	ADP
fnp-2819	204	9	the	the	DET
fnp-2819	204	10	potent	potent	ADJ
fnp-2819	204	11	hdac	hdac	NOUN
fnp-2819	204	12	inhibitor	inhibitor	NOUN
fnp-2819	204	13	tsa	tsa	NOUN
fnp-2819	204	14	not	not	PART
fnp-2819	204	15	only	only	ADV
fnp-2819	204	16	reduced	reduce	VERB
fnp-2819	204	17	the	the	DET
fnp-2819	204	18	frequencies	frequency	NOUN
fnp-2819	204	19	of	of	ADP
fnp-2819	204	20	th1	th1	PROPN
fnp-2819	204	21	,	,	PUNCT
fnp-2819	204	22	th17	th17	PROPN
fnp-2819	204	23	,	,	PUNCT
fnp-2819	204	24	and	and	CCONJ
fnp-2819	204	25	th1	th1	PROPN
fnp-2819	204	26	/	/	SYM
fnp-2819	204	27	th17	th17	PROPN
fnp-2819	204	28	cells	cell	NOUN
fnp-2819	204	29	in	in	ADP
fnp-2819	204	30	the	the	DET
fnp-2819	204	31	slo	slo	PROPN
fnp-2819	204	32	and	and	CCONJ
fnp-2819	204	33	their	their	PRON
fnp-2819	204	34	influx	influx	NOUN
fnp-2819	204	35	into	into	ADP
fnp-2819	204	36	the	the	DET
fnp-2819	204	37	cns	cns	NOUN
fnp-2819	204	38	but	but	CCONJ
fnp-2819	204	39	also	also	ADV
fnp-2819	204	40	induced	induce	VERB
fnp-2819	204	41	mog35	mog35	NOUN
fnp-2819	204	42	-	-	PUNCT
fnp-2819	204	43	55	55	NUM
fnp-2819	204	44	peptide	peptide	NOUN
fnp-2819	204	45	-	-	PUNCT
fnp-2819	204	46	specific	specific	ADJ
fnp-2819	204	47	t	t	NOUN
fnp-2819	204	48	cell	cell	NOUN
fnp-2819	204	49	tolerance	tolerance	NOUN
fnp-2819	204	50	(	(	PUNCT
fnp-2819	204	51	anergy	anergy	NOUN
fnp-2819	204	52	)	)	PUNCT
fnp-2819	204	53	in	in	ADP
fnp-2819	204	54	nod	nod	NOUN
fnp-2819	204	55	mice	mouse	NOUN
fnp-2819	204	56	(	(	PUNCT
fnp-2819	204	57	jayaraman	jayaraman	NOUN
fnp-2819	204	58	et	et	PROPN
fnp-2819	204	59	al	al	PROPN
fnp-2819	204	60	.	.	PROPN
fnp-2819	204	61	,	,	PUNCT
fnp-2819	204	62	2017	2017	NUM
fnp-2819	204	63	)	)	PUNCT
fnp-2819	204	64	.	.	PUNCT
fnp-2819	205	1	although	although	SCONJ
fnp-2819	205	2	anergy	anergy	PROPN
fnp-2819	205	3	was	be	AUX
fnp-2819	205	4	originally	originally	ADV
fnp-2819	205	5	reported	report	VERB
fnp-2819	205	6	in	in	ADP
fnp-2819	205	7	a	a	DET
fnp-2819	205	8	mouse	mouse	NOUN
fnp-2819	205	9	th1	th1	NOUN
fnp-2819	205	10	clone	clone	NOUN
fnp-2819	205	11	that	that	PRON
fnp-2819	205	12	was	be	AUX
fnp-2819	205	13	suboptimally	suboptimally	ADV
fnp-2819	205	14	activated	activate	VERB
fnp-2819	205	15	without	without	ADP
fnp-2819	205	16	co	co	NOUN
fnp-2819	205	17	-	-	NOUN
fnp-2819	205	18	stimulation	stimulation	NOUN
fnp-2819	205	19	in	in	ADP
fnp-2819	205	20	vitro	vitro	X
fnp-2819	205	21	(	(	PUNCT
fnp-2819	205	22	schwartz	schwartz	PROPN
fnp-2819	205	23	et	et	PROPN
fnp-2819	205	24	al	al	PROPN
fnp-2819	205	25	.	.	PROPN
fnp-2819	205	26	,	,	PUNCT
fnp-2819	205	27	1989	1989	NUM
fnp-2819	205	28	;	;	PUNCT
fnp-2819	205	29	jayaraman	jayaraman	NOUN
fnp-2819	205	30	et	et	PROPN
fnp-2819	205	31	al	al	PROPN
fnp-2819	205	32	.	.	PROPN
fnp-2819	205	33	,	,	PUNCT
fnp-2819	205	34	1992	1992	NUM
fnp-2819	205	35	)	)	PUNCT
fnp-2819	205	36	,	,	PUNCT
fnp-2819	205	37	the	the	DET
fnp-2819	205	38	underlying	underlying	ADJ
fnp-2819	205	39	mechanisms	mechanism	NOUN
fnp-2819	205	40	have	have	AUX
fnp-2819	205	41	not	not	PART
fnp-2819	205	42	been	be	AUX
fnp-2819	205	43	fully	fully	ADV
fnp-2819	205	44	deciphered	decipher	VERB
fnp-2819	205	45	.	.	PUNCT
fnp-2819	206	1	our	our	PRON
fnp-2819	206	2	investigation	investigation	NOUN
fnp-2819	206	3	unraveled	unravel	VERB
fnp-2819	206	4	a	a	DET
fnp-2819	206	5	good	good	ADJ
fnp-2819	206	6	correlation	correlation	NOUN
fnp-2819	206	7	between	between	ADP
fnp-2819	206	8	tsa	tsa	NOUN
fnp-2819	206	9	-	-	PUNCT
fnp-2819	206	10	mediated	mediate	VERB
fnp-2819	206	11	neuroprotection	neuroprotection	NOUN
fnp-2819	206	12	and	and	CCONJ
fnp-2819	206	13	downregulation	downregulation	NOUN
fnp-2819	206	14	of	of	ADP
fnp-2819	206	15	selected	select	VERB
fnp-2819	206	16	immune	immune	ADJ
fnp-2819	206	17	response	response	NOUN
fnp-2819	206	18	-	-	PUNCT
fnp-2819	206	19	related	relate	VERB
fnp-2819	206	20	genes	gene	NOUN
fnp-2819	206	21	both	both	CCONJ
fnp-2819	206	22	in	in	ADP
fnp-2819	206	23	the	the	DET
fnp-2819	206	24	cns	cns	NOUN
fnp-2819	206	25	and	and	CCONJ
fnp-2819	206	26	slo	slo	PROPN
fnp-2819	206	27	.	.	PUNCT
fnp-2819	207	1	whereas	whereas	SCONJ
fnp-2819	207	2	these	these	DET
fnp-2819	207	3	data	datum	NOUN
fnp-2819	207	4	may	may	AUX
fnp-2819	207	5	not	not	PART
fnp-2819	207	6	directly	directly	ADV
fnp-2819	207	7	impinge	impinge	VERB
fnp-2819	207	8	upon	upon	SCONJ
fnp-2819	207	9	histone	histone	NOUN
fnp-2819	207	10	modifier	modifier	NOUN
fnp-2819	207	11	-	-	PUNCT
fnp-2819	207	12	facilitated	facilitate	VERB
fnp-2819	207	13	mog35	mog35	NOUN
fnp-2819	207	14	-	-	PUNCT
fnp-2819	207	15	55	55	NUM
fnp-2819	207	16	peptide	peptide	NOUN
fnp-2819	207	17	-	-	PUNCT
fnp-2819	207	18	specific	specific	ADJ
fnp-2819	207	19	t	t	NOUN
fnp-2819	207	20	cell	cell	NOUN
fnp-2819	207	21	tolerance	tolerance	NOUN
fnp-2819	207	22	,	,	PUNCT
fnp-2819	207	23	they	they	PRON
fnp-2819	207	24	highlight	highlight	VERB
fnp-2819	207	25	the	the	DET
fnp-2819	207	26	possible	possible	ADJ
fnp-2819	207	27	impact	impact	NOUN
fnp-2819	207	28	of	of	ADP
fnp-2819	207	29	differential	differential	ADJ
fnp-2819	207	30	gene	gene	NOUN
fnp-2819	207	31	expression	expression	NOUN
fnp-2819	207	32	on	on	ADP
fnp-2819	207	33	peae	peae	PROPN
fnp-2819	207	34	.	.	PUNCT
fnp-2819	208	1	the	the	DET
fnp-2819	208	2	epigenetic	epigenetic	ADJ
fnp-2819	208	3	approach	approach	NOUN
fnp-2819	208	4	unraveled	unravel	VERB
fnp-2819	208	5	an	an	DET
fnp-2819	208	6	inverse	inverse	NOUN
fnp-2819	208	7	relationship	relationship	NOUN
fnp-2819	208	8	between	between	ADP
fnp-2819	208	9	the	the	DET
fnp-2819	208	10	expression	expression	NOUN
fnp-2819	208	11	levels	level	NOUN
fnp-2819	208	12	of	of	ADP
fnp-2819	208	13	a	a	DET
fnp-2819	208	14	small	small	ADJ
fnp-2819	208	15	set	set	NOUN
fnp-2819	208	16	of	of	ADP
fnp-2819	208	17	genes	gene	NOUN
fnp-2819	208	18	and	and	CCONJ
fnp-2819	208	19	neuroprotection	neuroprotection	NOUN
fnp-2819	208	20	.	.	PUNCT
fnp-2819	209	1	in	in	ADP
fnp-2819	209	2	the	the	DET
fnp-2819	209	3	cns	cns	NOUN
fnp-2819	209	4	of	of	ADP
fnp-2819	209	5	peae	peae	PROPN
fnp-2819	209	6	nod	nod	PROPN
fnp-2819	209	7	mice	mouse	NOUN
fnp-2819	209	8	,	,	PUNCT
fnp-2819	209	9	il17a	il17a	X
fnp-2819	209	10	expression	expression	NOUN
fnp-2819	209	11	was	be	AUX
fnp-2819	209	12	upregulated	upregulate	VERB
fnp-2819	209	13	for	for	ADP
fnp-2819	209	14	over	over	ADP
fnp-2819	209	15	a	a	PRON
fnp-2819	209	16	month	month	NOUN
fnp-2819	209	17	(	(	PUNCT
fnp-2819	209	18	fig	fig	NOUN
fnp-2819	209	19	.	.	PUNCT
fnp-2819	210	1	2	2	NUM
fnp-2819	210	2	)	)	PUNCT
fnp-2819	210	3	,	,	PUNCT
fnp-2819	210	4	unlike	unlike	ADP
fnp-2819	210	5	its	its	PRON
fnp-2819	210	6	expression	expression	NOUN
fnp-2819	210	7	at	at	ADP
fnp-2819	210	8	the	the	DET
fnp-2819	210	9	peak	peak	NOUN
fnp-2819	210	10	of	of	ADP
fnp-2819	210	11	the	the	DET
fnp-2819	210	12	monophasic	monophasic	ADJ
fnp-2819	210	13	eae	eae	PROPN
fnp-2819	210	14	(	(	PUNCT
fnp-2819	210	15	kreymborg	kreymborg	PROPN
fnp-2819	210	16	et	et	PROPN
fnp-2819	210	17	al	al	PROPN
fnp-2819	210	18	.	.	PROPN
fnp-2819	210	19	,	,	PUNCT
fnp-2819	210	20	2007	2007	NUM
fnp-2819	210	21	;	;	PUNCT
fnp-2819	210	22	evangelidou	evangelidou	NOUN
fnp-2819	210	23	et	et	PROPN
fnp-2819	210	24	al	al	PROPN
fnp-2819	210	25	.	.	PROPN
fnp-2819	210	26	,	,	PUNCT
fnp-2819	210	27	2014	2014	NUM
fnp-2819	210	28	;	;	PUNCT
fnp-2819	210	29	borjini	borjini	NOUN
fnp-2819	210	30	et	et	PROPN
fnp-2819	210	31	al	al	PROPN
fnp-2819	210	32	.	.	PROPN
fnp-2819	210	33	,	,	PUNCT
fnp-2819	210	34	2016	2016	NUM
fnp-2819	210	35	)	)	PUNCT
fnp-2819	210	36	.	.	PUNCT
fnp-2819	211	1	prolonged	prolong	VERB
fnp-2819	211	2	expression	expression	NOUN
fnp-2819	211	3	of	of	ADP
fnp-2819	211	4	nos2	nos2	PROPN
fnp-2819	211	5	in	in	ADP
fnp-2819	211	6	the	the	DET
fnp-2819	211	7	cns	cns	PROPN
fnp-2819	211	8	(	(	PUNCT
fnp-2819	211	9	fig	fig	NOUN
fnp-2819	211	10	.	.	PUNCT
fnp-2819	211	11	2b	2b	NOUN
fnp-2819	211	12	)	)	PUNCT
fnp-2819	211	13	is	be	AUX
fnp-2819	211	14	congruent	congruent	ADJ
fnp-2819	211	15	with	with	ADP
fnp-2819	211	16	the	the	DET
fnp-2819	211	17	association	association	NOUN
fnp-2819	211	18	of	of	ADP
fnp-2819	211	19	inos	ino	NOUN
fnp-2819	211	20	-	-	PUNCT
fnp-2819	211	21	positive	positive	ADJ
fnp-2819	211	22	macrophages	macrophage	NOUN
fnp-2819	211	23	and	and	CCONJ
fnp-2819	211	24	glial	glial	ADJ
fnp-2819	211	25	cells	cell	NOUN
fnp-2819	211	26	in	in	ADP
fnp-2819	211	27	demyelinating	demyelinate	VERB
fnp-2819	211	28	pathology	pathology	NOUN
fnp-2819	211	29	(	(	PUNCT
fnp-2819	211	30	tran	tran	PROPN
fnp-2819	211	31	et	et	PROPN
fnp-2819	211	32	al	al	PROPN
fnp-2819	211	33	.	.	PROPN
fnp-2819	211	34	,	,	PUNCT
fnp-2819	211	35	1997	1997	NUM
fnp-2819	211	36	)	)	PUNCT
fnp-2819	211	37	.	.	PUNCT
fnp-2819	212	1	in	in	ADP
fnp-2819	212	2	addition	addition	NOUN
fnp-2819	212	3	to	to	ADP
fnp-2819	212	4	the	the	DET
fnp-2819	212	5	nos2	nos2	NOUN
fnp-2819	212	6	(	(	PUNCT
fnp-2819	212	7	fig	fig	NOUN
fnp-2819	212	8	.	.	PUNCT
fnp-2819	212	9	3c	3c	NUM
fnp-2819	212	10	)	)	PUNCT
fnp-2819	212	11	,	,	PUNCT
fnp-2819	212	12	the	the	DET
fnp-2819	212	13	subunits	subunit	NOUN
fnp-2819	212	14	of	of	ADP
fnp-2819	212	15	il-27	il-27	NUM
fnp-2819	212	16	,	,	PUNCT
fnp-2819	212	17	namely	namely	ADV
fnp-2819	212	18	il-27p28	il-27p28	NOUN
fnp-2819	212	19	,	,	PUNCT
fnp-2819	212	20	and	and	CCONJ
fnp-2819	212	21	il-27ebi3	il-27ebi3	NOUN
fnp-2819	212	22	,	,	PUNCT
fnp-2819	212	23	were	be	AUX
fnp-2819	212	24	prominently	prominently	ADV
fnp-2819	212	25	upregulated	upregulate	VERB
fnp-2819	212	26	at	at	ADP
fnp-2819	212	27	the	the	DET
fnp-2819	212	28	mrna	mrna	PROPN
fnp-2819	212	29	level	level	NOUN
fnp-2819	212	30	in	in	ADP
fnp-2819	212	31	the	the	DET
fnp-2819	212	32	slo	slo	PROPN
fnp-2819	212	33	(	(	PUNCT
fnp-2819	212	34	fig	fig	NOUN
fnp-2819	212	35	.	.	PUNCT
fnp-2819	213	1	3b	3b	NUM
fnp-2819	213	2	-	-	PUNCT
fnp-2819	213	3	c	c	NOUN
fnp-2819	213	4	)	)	PUNCT
fnp-2819	213	5	.	.	PUNCT
fnp-2819	214	1	this	this	PRON
fnp-2819	214	2	is	be	AUX
fnp-2819	214	3	consistent	consistent	ADJ
fnp-2819	214	4	with	with	ADP
fnp-2819	214	5	an	an	DET
fnp-2819	214	6	encephalitogenic	encephalitogenic	ADJ
fnp-2819	214	7	role	role	NOUN
fnp-2819	214	8	of	of	ADP
fnp-2819	214	9	il-27	il-27	NUM
fnp-2819	214	10	suggested	suggest	VERB
fnp-2819	214	11	by	by	ADP
fnp-2819	214	12	the	the	DET
fnp-2819	214	13	suppression	suppression	NOUN
fnp-2819	214	14	of	of	ADP
fnp-2819	214	15	the	the	DET
fnp-2819	214	16	ongoing	ongoing	ADJ
fnp-2819	214	17	eae	eae	PROPN
fnp-2819	214	18	following	follow	VERB
fnp-2819	214	19	administration	administration	NOUN
fnp-2819	214	20	of	of	ADP
fnp-2819	214	21	the	the	DET
fnp-2819	214	22	neutralizing	neutralizing	ADJ
fnp-2819	214	23	antibody	antibody	NOUN
fnp-2819	214	24	against	against	ADP
fnp-2819	214	25	the	the	DET
fnp-2819	214	26	il-27p28	il-27p28	NOUN
fnp-2819	214	27	subunit	subunit	NOUN
fnp-2819	214	28	(	(	PUNCT
fnp-2819	214	29	goldberg	goldberg	PROPN
fnp-2819	214	30	et	et	PROPN
fnp-2819	214	31	al	al	PROPN
fnp-2819	214	32	.	.	PROPN
fnp-2819	214	33	,	,	PUNCT
fnp-2819	214	34	2004	2004	NUM
fnp-2819	214	35	)	)	PUNCT
fnp-2819	214	36	.	.	PUNCT
fnp-2819	215	1	besides	besides	SCONJ
fnp-2819	215	2	,	,	PUNCT
fnp-2819	215	3	tsa	tsa	NOUN
fnp-2819	215	4	treatment	treatment	NOUN
fnp-2819	215	5	reduced	reduce	VERB
fnp-2819	215	6	the	the	DET
fnp-2819	215	7	steady	steady	ADJ
fnp-2819	215	8	-	-	PUNCT
fnp-2819	215	9	state	state	NOUN
fnp-2819	215	10	expression	expression	NOUN
fnp-2819	215	11	of	of	ADP
fnp-2819	215	12	mif	mif	PROPN
fnp-2819	215	13	in	in	ADP
fnp-2819	215	14	both	both	CCONJ
fnp-2819	215	15	the	the	DET
fnp-2819	215	16	cns	cns	PROPN
fnp-2819	215	17	and	and	CCONJ
fnp-2819	215	18	slo	slo	PROPN
fnp-2819	215	19	(	(	PUNCT
fnp-2819	215	20	fig	fig	NOUN
fnp-2819	215	21	.	.	PUNCT
fnp-2819	216	1	2e	2e	NUM
fnp-2819	216	2	,	,	PUNCT
fnp-2819	216	3	fig	fig	NOUN
fnp-2819	216	4	.	.	PUNCT
fnp-2819	217	1	3e	3e	NOUN
fnp-2819	217	2	)	)	PUNCT
fnp-2819	217	3	,	,	PUNCT
fnp-2819	218	1	consistent	consistent	ADJ
fnp-2819	218	2	with	with	ADP
fnp-2819	218	3	a	a	DET
fnp-2819	218	4	proposed	propose	VERB
fnp-2819	218	5	pathogenic	pathogenic	ADJ
fnp-2819	218	6	role	role	NOUN
fnp-2819	218	7	of	of	ADP
fnp-2819	218	8	mif	mif	PROPN
fnp-2819	218	9	in	in	ADP
fnp-2819	218	10	monophasic	monophasic	ADJ
fnp-2819	218	11	eae	eae	PROPN
fnp-2819	218	12	(	(	PUNCT
fnp-2819	218	13	powell	powell	PROPN
fnp-2819	218	14	et	et	PROPN
fnp-2819	218	15	al	al	PROPN
fnp-2819	218	16	.	.	PROPN
fnp-2819	218	17	,	,	PUNCT
fnp-2819	218	18	2005	2005	NUM
fnp-2819	218	19	)	)	PUNCT
fnp-2819	218	20	.	.	PUNCT
fnp-2819	219	1	we	we	PRON
fnp-2819	219	2	have	have	AUX
fnp-2819	219	3	previously	previously	ADV
fnp-2819	219	4	shown	show	VERB
fnp-2819	219	5	that	that	SCONJ
fnp-2819	219	6	tsa	tsa	NOUN
fnp-2819	219	7	treatment	treatment	NOUN
fnp-2819	219	8	diminished	diminish	VERB
fnp-2819	219	9	the	the	DET
fnp-2819	219	10	numbers	number	NOUN
fnp-2819	219	11	of	of	ADP
fnp-2819	219	12	splenocytes	splenocyte	NOUN
fnp-2819	219	13	expressing	express	VERB
fnp-2819	219	14	the	the	DET
fnp-2819	219	15	co	co	ADJ
fnp-2819	219	16	-	-	ADJ
fnp-2819	219	17	inhibitory	inhibitory	ADJ
fnp-2819	219	18	ligand	ligand	NOUN
fnp-2819	219	19	cd274	cd274	PROPN
fnp-2819	219	20	(	(	PUNCT
fnp-2819	219	21	pd	pd	PROPN
fnp-2819	219	22	-	-	PUNCT
fnp-2819	219	23	l1	l1	PROPN
fnp-2819	219	24	)	)	PUNCT
fnp-2819	219	25	(	(	PUNCT
fnp-2819	219	26	jayaraman	jayaraman	NOUN
fnp-2819	219	27	et	et	PROPN
fnp-2819	219	28	al	al	PROPN
fnp-2819	219	29	.	.	PROPN
fnp-2819	219	30	,	,	PUNCT
fnp-2819	219	31	2018	2018	NUM
fnp-2819	219	32	)	)	PUNCT
fnp-2819	219	33	.	.	PUNCT
fnp-2819	220	1	consistently	consistently	ADV
fnp-2819	220	2	,	,	PUNCT
fnp-2819	220	3	the	the	DET
fnp-2819	220	4	cd274	cd274	PROPN
fnp-2819	220	5	mrna	mrna	PROPN
fnp-2819	220	6	level	level	NOUN
fnp-2819	220	7	was	be	AUX
fnp-2819	220	8	also	also	ADV
fnp-2819	220	9	repressed	repress	VERB
fnp-2819	220	10	in	in	ADP
fnp-2819	220	11	the	the	DET
fnp-2819	220	12	cns	cns	PROPN
fnp-2819	220	13	(	(	PUNCT
fnp-2819	220	14	fig	fig	NOUN
fnp-2819	220	15	.	.	PUNCT
fnp-2819	221	1	2	2	NUM
fnp-2819	221	2	g	g	NOUN
fnp-2819	221	3	)	)	PUNCT
fnp-2819	221	4	and	and	CCONJ
fnp-2819	221	5	slo	slo	PROPN
fnp-2819	221	6	(	(	PUNCT
fnp-2819	221	7	fig	fig	PROPN
fnp-2819	221	8	.	.	PUNCT
fnp-2819	221	9	3f	3f	PROPN
fnp-2819	221	10	)	)	PUNCT
fnp-2819	221	11	of	of	ADP
fnp-2819	221	12	tsa	tsa	PROPN
fnp-2819	221	13	-	-	PUNCT
fnp-2819	221	14	treated	treat	VERB
fnp-2819	221	15	peae	peae	ADJ
fnp-2819	221	16	mice	mouse	NOUN
fnp-2819	221	17	,	,	PUNCT
fnp-2819	221	18	suggesting	suggest	VERB
fnp-2819	221	19	a	a	DET
fnp-2819	221	20	role	role	NOUN
fnp-2819	221	21	for	for	ADP
fnp-2819	221	22	this	this	DET
fnp-2819	221	23	co	co	ADJ
fnp-2819	221	24	-	-	ADJ
fnp-2819	221	25	inhibitory	inhibitory	ADJ
fnp-2819	221	26	ligand	ligand	NOUN
fnp-2819	221	27	in	in	ADP
fnp-2819	221	28	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	221	29	,	,	PUNCT
fnp-2819	221	30	as	as	SCONJ
fnp-2819	221	31	proposed	propose	VERB
fnp-2819	221	32	(	(	PUNCT
fnp-2819	221	33	jayaraman	jayaraman	NOUN
fnp-2819	221	34	et	et	PROPN
fnp-2819	221	35	al	al	PROPN
fnp-2819	221	36	.	.	PROPN
fnp-2819	221	37	,	,	PUNCT
fnp-2819	221	38	2018	2018	NUM
fnp-2819	221	39	)	)	PUNCT
fnp-2819	221	40	.	.	PUNCT
fnp-2819	222	1	also	also	ADV
fnp-2819	222	2	,	,	PUNCT
fnp-2819	222	3	the	the	DET
fnp-2819	222	4	expression	expression	NOUN
fnp-2819	222	5	of	of	ADP
fnp-2819	222	6	ahr	ahr	PROPN
fnp-2819	222	7	,	,	PUNCT
fnp-2819	222	8	uniquely	uniquely	ADV
fnp-2819	222	9	required	require	VERB
fnp-2819	222	10	for	for	ADP
fnp-2819	222	11	the	the	DET
fnp-2819	222	12	generation	generation	NOUN
fnp-2819	222	13	of	of	ADP
fnp-2819	222	14	t	t	PROPN
fnp-2819	222	15	cells	cell	NOUN
fnp-2819	222	16	responsible	responsible	ADJ
fnp-2819	222	17	for	for	ADP
fnp-2819	222	18	the	the	DET
fnp-2819	222	19	late	late	ADJ
fnp-2819	222	20	-	-	PUNCT
fnp-2819	222	21	onset	onset	NOUN
fnp-2819	222	22	eae	eae	NOUN
fnp-2819	222	23	(	(	PUNCT
fnp-2819	222	24	nakahama	nakahama	NOUN
fnp-2819	222	25	et	et	PROPN
fnp-2819	222	26	al	al	PROPN
fnp-2819	222	27	.	.	PROPN
fnp-2819	222	28	,	,	PUNCT
fnp-2819	222	29	2013	2013	NUM
fnp-2819	222	30	)	)	PUNCT
fnp-2819	222	31	was	be	AUX
fnp-2819	222	32	diminished	diminish	VERB
fnp-2819	222	33	in	in	ADP
fnp-2819	222	34	mice	mouse	NOUN
fnp-2819	222	35	protected	protect	VERB
fnp-2819	222	36	by	by	ADP
fnp-2819	222	37	tsa	tsa	NOUN
fnp-2819	222	38	treatment	treatment	NOUN
fnp-2819	222	39	(	(	PUNCT
fnp-2819	222	40	fig	fig	NOUN
fnp-2819	222	41	.	.	PUNCT
fnp-2819	223	1	2f	2f	NUM
fnp-2819	223	2	)	)	PUNCT
fnp-2819	223	3	.	.	PUNCT
fnp-2819	224	1	collectively	collectively	ADV
fnp-2819	224	2	,	,	PUNCT
fnp-2819	224	3	the	the	DET
fnp-2819	224	4	tsa	tsa	NOUN
fnp-2819	224	5	-	-	PUNCT
fnp-2819	224	6	mediated	mediate	VERB
fnp-2819	224	7	downregulation	downregulation	NOUN
fnp-2819	224	8	of	of	ADP
fnp-2819	224	9	both	both	CCONJ
fnp-2819	224	10	inducible	inducible	ADJ
fnp-2819	224	11	and	and	CCONJ
fnp-2819	224	12	constitutively	constitutively	ADV
fnp-2819	224	13	expressed	express	VERB
fnp-2819	224	14	genes	gene	NOUN
fnp-2819	224	15	appears	appear	VERB
fnp-2819	224	16	to	to	PART
fnp-2819	224	17	be	be	AUX
fnp-2819	224	18	inversely	inversely	ADV
fnp-2819	224	19	proportional	proportional	ADJ
fnp-2819	224	20	to	to	ADP
fnp-2819	224	21	the	the	DET
fnp-2819	224	22	severity	severity	NOUN
fnp-2819	224	23	of	of	ADP
fnp-2819	224	24	the	the	DET
fnp-2819	224	25	neuronal	neuronal	ADJ
fnp-2819	224	26	disease	disease	NOUN
fnp-2819	224	27	.	.	PUNCT
fnp-2819	225	1	however	however	ADV
fnp-2819	225	2	,	,	PUNCT
fnp-2819	225	3	it	it	PRON
fnp-2819	225	4	remains	remain	VERB
fnp-2819	225	5	to	to	PART
fnp-2819	225	6	be	be	AUX
fnp-2819	225	7	determined	determine	VERB
fnp-2819	225	8	whether	whether	SCONJ
fnp-2819	225	9	the	the	DET
fnp-2819	225	10	expression	expression	NOUN
fnp-2819	225	11	levels	level	NOUN
fnp-2819	225	12	of	of	ADP
fnp-2819	225	13	these	these	DET
fnp-2819	225	14	genes	gene	NOUN
fnp-2819	225	15	may	may	AUX
fnp-2819	225	16	serve	serve	VERB
fnp-2819	225	17	as	as	ADP
fnp-2819	225	18	biomarkers	biomarker	NOUN
fnp-2819	225	19	for	for	ADP
fnp-2819	225	20	the	the	DET
fnp-2819	225	21	diagnosis	diagnosis	NOUN
fnp-2819	225	22	of	of	ADP
fnp-2819	225	23	ms	ms	PROPN
fnp-2819	225	24	.	.	PROPN
fnp-2819	226	1	nevertheless	nevertheless	ADV
fnp-2819	226	2	,	,	PUNCT
fnp-2819	226	3	the	the	DET
fnp-2819	226	4	information	information	NOUN
fnp-2819	226	5	uncovered	uncover	VERB
fnp-2819	226	6	in	in	ADP
fnp-2819	226	7	the	the	DET
fnp-2819	226	8	nod	nod	PROPN
fnp-2819	226	9	mouse	mouse	NOUN
fnp-2819	226	10	model	model	NOUN
fnp-2819	226	11	may	may	AUX
fnp-2819	226	12	provide	provide	VERB
fnp-2819	226	13	a	a	DET
fnp-2819	226	14	framework	framework	NOUN
fnp-2819	226	15	for	for	ADP
fnp-2819	226	16	potential	potential	ADJ
fnp-2819	226	17	ms	ms	PROPN
fnp-2819	226	18	treatment	treatment	NOUN
fnp-2819	226	19	,	,	PUNCT
fnp-2819	226	20	typically	typically	ADV
fnp-2819	226	21	diagnosed	diagnose	VERB
fnp-2819	226	22	as	as	ADP
fnp-2819	226	23	clinically	clinically	ADV
fnp-2819	226	24	isolated	isolate	VERB
fnp-2819	226	25	syndrome	syndrome	NOUN
fnp-2819	226	26	followed	follow	VERB
fnp-2819	226	27	by	by	ADP
fnp-2819	226	28	years	year	NOUN
fnp-2819	226	29	of	of	ADP
fnp-2819	226	30	asymptomatic	asymptomatic	ADJ
fnp-2819	226	31	period	period	NOUN
fnp-2819	226	32	(	(	PUNCT
fnp-2819	226	33	dendrou	dendrou	PROPN
fnp-2819	226	34	et	et	PROPN
fnp-2819	226	35	al	al	PROPN
fnp-2819	226	36	.	.	PROPN
fnp-2819	226	37	,	,	PUNCT
fnp-2819	226	38	2015	2015	NUM
fnp-2819	226	39	)	)	PUNCT
fnp-2819	226	40	.	.	PUNCT
fnp-2819	227	1	the	the	DET
fnp-2819	227	2	upregulation	upregulation	NOUN
fnp-2819	227	3	of	of	ADP
fnp-2819	227	4	the	the	DET
fnp-2819	227	5	transcription	transcription	NOUN
fnp-2819	227	6	of	of	ADP
fnp-2819	227	7	hdac11	hdac11	NOUN
fnp-2819	227	8	in	in	ADP
fnp-2819	227	9	a	a	DET
fnp-2819	227	10	cns	cns	NOUN
fnp-2819	227	11	-	-	PUNCT
fnp-2819	227	12	specific	specific	ADJ
fnp-2819	227	13	fashion	fashion	NOUN
fnp-2819	227	14	in	in	ADP
fnp-2819	227	15	mice	mouse	NOUN
fnp-2819	227	16	immunized	immunize	VERB
fnp-2819	227	17	with	with	ADP
fnp-2819	227	18	mog35	mog35	NOUN
fnp-2819	227	19	-	-	PUNCT
fnp-2819	227	20	55	55	NUM
fnp-2819	227	21	(	(	PUNCT
fnp-2819	227	22	fig	fig	NOUN
fnp-2819	227	23	.	.	PUNCT
fnp-2819	227	24	5	5	NUM
fnp-2819	227	25	)	)	PUNCT
fnp-2819	227	26	represents	represent	VERB
fnp-2819	227	27	the	the	DET
fnp-2819	227	28	first	first	ADJ
fnp-2819	227	29	report	report	NOUN
fnp-2819	227	30	of	of	ADP
fnp-2819	227	31	differential	differential	ADJ
fnp-2819	227	32	expression	expression	NOUN
fnp-2819	227	33	of	of	ADP
fnp-2819	227	34	hdac	hdac	NOUN
fnp-2819	227	35	genes	gene	NOUN
fnp-2819	227	36	in	in	ADP
fnp-2819	227	37	vivo	vivo	NOUN
fnp-2819	227	38	.	.	PUNCT
fnp-2819	228	1	although	although	SCONJ
fnp-2819	228	2	the	the	DET
fnp-2819	228	3	non	non	ADJ
fnp-2819	228	4	-	-	ADJ
fnp-2819	228	5	selective	selective	ADJ
fnp-2819	228	6	hdac	hdac	NOUN
fnp-2819	228	7	inhibitor	inhibitor	NOUN
fnp-2819	228	8	tsa	tsa	NOUN
fnp-2819	228	9	did	do	AUX
fnp-2819	228	10	not	not	PART
fnp-2819	228	11	diminish	diminish	VERB
fnp-2819	228	12	the	the	DET
fnp-2819	228	13	hdac11	hdac11	NOUN
fnp-2819	228	14	enzymatic	enzymatic	ADJ
fnp-2819	228	15	activity	activity	NOUN
fnp-2819	228	16	in	in	ADP
fnp-2819	228	17	vitro	vitro	X
fnp-2819	228	18	(	(	PUNCT
fnp-2819	228	19	bradner	bradner	NOUN
fnp-2819	228	20	et	et	PROPN
fnp-2819	228	21	al	al	PROPN
fnp-2819	228	22	.	.	PROPN
fnp-2819	228	23	,	,	PUNCT
fnp-2819	228	24	2010	2010	NUM
fnp-2819	228	25	)	)	PUNCT
fnp-2819	228	26	,	,	PUNCT
fnp-2819	228	27	our	our	PRON
fnp-2819	228	28	data	datum	NOUN
fnp-2819	228	29	demonstrated	demonstrate	VERB
fnp-2819	228	30	the	the	DET
fnp-2819	228	31	control	control	NOUN
fnp-2819	228	32	of	of	ADP
fnp-2819	228	33	hdac11	hdac11	NOUN
fnp-2819	228	34	by	by	ADP
fnp-2819	228	35	tsa	tsa	NOUN
fnp-2819	228	36	at	at	ADP
fnp-2819	228	37	the	the	DET
fnp-2819	228	38	transcriptional	transcriptional	ADJ
fnp-2819	228	39	level	level	NOUN
fnp-2819	228	40	.	.	PUNCT
fnp-2819	229	1	since	since	SCONJ
fnp-2819	229	2	hdac11	hdac11	NOUN
fnp-2819	229	3	gene	gene	NOUN
fnp-2819	229	4	expression	expression	NOUN
fnp-2819	229	5	was	be	AUX
fnp-2819	229	6	determined	determine	VERB
fnp-2819	229	7	in	in	ADP
fnp-2819	229	8	the	the	DET
fnp-2819	229	9	sc	sc	PROPN
fnp-2819	229	10	devoid	devoid	ADJ
fnp-2819	229	11	of	of	ADP
fnp-2819	229	12	peripheral	peripheral	ADJ
fnp-2819	229	13	blood	blood	NOUN
fnp-2819	229	14	contamination	contamination	NOUN
fnp-2819	229	15	,	,	PUNCT
fnp-2819	229	16	its	its	PRON
fnp-2819	229	17	reduction	reduction	NOUN
fnp-2819	229	18	appears	appear	VERB
fnp-2819	229	19	to	to	PART
fnp-2819	229	20	be	be	AUX
fnp-2819	229	21	a	a	DET
fnp-2819	229	22	direct	direct	ADJ
fnp-2819	229	23	effect	effect	NOUN
fnp-2819	229	24	of	of	ADP
fnp-2819	229	25	tsa	tsa	NOUN
fnp-2819	229	26	on	on	ADP
fnp-2819	229	27	the	the	DET
fnp-2819	229	28	cns	cns	NOUN
fnp-2819	229	29	resident	resident	NOUN
fnp-2819	229	30	cells	cell	NOUN
fnp-2819	229	31	.	.	PUNCT
fnp-2819	230	1	although	although	SCONJ
fnp-2819	230	2	we	we	PRON
fnp-2819	230	3	have	have	AUX
fnp-2819	230	4	not	not	PART
fnp-2819	230	5	identified	identify	VERB
fnp-2819	230	6	the	the	DET
fnp-2819	230	7	cellular	cellular	ADJ
fnp-2819	230	8	source	source	NOUN
fnp-2819	230	9	of	of	ADP
fnp-2819	230	10	hdac11	hdac11	NOUN
fnp-2819	230	11	in	in	ADP
fnp-2819	230	12	the	the	DET
fnp-2819	230	13	spinal	spinal	NOUN
fnp-2819	230	14	cord	cord	NOUN
fnp-2819	230	15	,	,	PUNCT
fnp-2819	230	16	previous	previous	ADJ
fnp-2819	230	17	work	work	NOUN
fnp-2819	230	18	suggested	suggest	VERB
fnp-2819	230	19	that	that	SCONJ
fnp-2819	230	20	hdac11	hdac11	NOUN
fnp-2819	230	21	knockdown	knockdown	NOUN
fnp-2819	230	22	increased	increase	VERB
fnp-2819	230	23	il10	il10	PROPN
fnp-2819	230	24	expression	expression	NOUN
fnp-2819	230	25	in	in	ADP
fnp-2819	230	26	peripheral	peripheral	ADJ
fnp-2819	230	27	antigen	antigen	NOUN
fnp-2819	230	28	-	-	PUNCT
fnp-2819	230	29	presenting	present	VERB
fnp-2819	230	30	cells	cell	NOUN
fnp-2819	230	31	resulting	result	VERB
fnp-2819	230	32	in	in	ADP
fnp-2819	230	33	immunosuppression	immunosuppression	NOUN
fnp-2819	230	34	in	in	ADP
fnp-2819	230	35	vitro	vitro	X
fnp-2819	230	36	(	(	PUNCT
fnp-2819	230	37	villagra	villagra	PROPN
fnp-2819	230	38	et	et	PROPN
fnp-2819	230	39	al	al	PROPN
fnp-2819	230	40	.	.	PROPN
fnp-2819	230	41	,	,	PUNCT
fnp-2819	230	42	2009	2009	NUM
fnp-2819	230	43	)	)	PUNCT
fnp-2819	230	44	.	.	PUNCT
fnp-2819	231	1	in	in	ADP
fnp-2819	231	2	contrast	contrast	NOUN
fnp-2819	231	3	,	,	PUNCT
fnp-2819	231	4	tsa	tsa	NOUN
fnp-2819	231	5	-	-	PUNCT
fnp-2819	231	6	induced	induce	VERB
fnp-2819	231	7	tolerance	tolerance	NOUN
fnp-2819	231	8	in	in	ADP
fnp-2819	231	9	mog35	mog35	NOUN
fnp-2819	231	10	-	-	PUNCT
fnp-2819	231	11	55	55	NUM
fnp-2819	231	12	-	-	PUNCT
fnp-2819	231	13	specific	specific	ADJ
fnp-2819	231	14	t	t	NOUN
fnp-2819	231	15	lymphocytes	lymphocyte	NOUN
fnp-2819	231	16	(	(	PUNCT
fnp-2819	231	17	jayaraman	jayaraman	NOUN
fnp-2819	231	18	et	et	PROPN
fnp-2819	231	19	al	al	PROPN
fnp-2819	231	20	.	.	PROPN
fnp-2819	231	21	,	,	PUNCT
fnp-2819	231	22	2017	2017	NUM
fnp-2819	231	23	)	)	PUNCT
fnp-2819	231	24	did	do	AUX
fnp-2819	231	25	not	not	PART
fnp-2819	231	26	accompany	accompany	VERB
fnp-2819	231	27	the	the	DET
fnp-2819	231	28	upregulated	upregulated	ADJ
fnp-2819	231	29	transcription	transcription	NOUN
fnp-2819	231	30	of	of	ADP
fnp-2819	231	31	il10	il10	PROPN
fnp-2819	231	32	in	in	ADP
fnp-2819	231	33	the	the	DET
fnp-2819	231	34	cns	cns	NOUN
fnp-2819	231	35	or	or	CCONJ
fnp-2819	231	36	slo	slo	PROPN
fnp-2819	231	37	(	(	PUNCT
fnp-2819	231	38	see	see	VERB
fnp-2819	231	39	supplementary	supplementary	ADJ
fnp-2819	231	40	fig	fig	NOUN
fnp-2819	231	41	.	.	PUNCT
fnp-2819	232	1	1	1	NUM
fnp-2819	232	2	)	)	PUNCT
fnp-2819	232	3	.	.	PUNCT
fnp-2819	233	1	although	although	SCONJ
fnp-2819	233	2	the	the	DET
fnp-2819	233	3	deletion	deletion	NOUN
fnp-2819	233	4	of	of	ADP
fnp-2819	233	5	hdac1	hdac1	NOUN
fnp-2819	233	6	selectively	selectively	ADV
fnp-2819	233	7	in	in	ADP
fnp-2819	233	8	t	t	PROPN
fnp-2819	233	9	cells	cell	NOUN
fnp-2819	233	10	was	be	AUX
fnp-2819	233	11	reported	report	VERB
fnp-2819	233	12	to	to	PART
fnp-2819	233	13	prevent	prevent	VERB
fnp-2819	233	14	eae	eae	PROPN
fnp-2819	233	15	(	(	PUNCT
fnp-2819	233	16	göschl	göschl	VERB
fnp-2819	233	17	et	et	PROPN
fnp-2819	233	18	al	al	PROPN
fnp-2819	233	19	.	.	PROPN
fnp-2819	233	20	,	,	PUNCT
fnp-2819	233	21	2018	2018	NUM
fnp-2819	233	22	)	)	PUNCT
fnp-2819	233	23	,	,	PUNCT
fnp-2819	233	24	immunization	immunization	NOUN
fnp-2819	233	25	with	with	ADP
fnp-2819	233	26	mog35	mog35	NOUN
fnp-2819	233	27	-	-	SYM
fnp-2819	233	28	55	55	NUM
fnp-2819	233	29	neither	neither	CCONJ
fnp-2819	233	30	upregulated	upregulate	VERB
fnp-2819	233	31	the	the	DET
fnp-2819	233	32	expression	expression	NOUN
fnp-2819	233	33	of	of	ADP
fnp-2819	233	34	this	this	DET
fnp-2819	233	35	gene	gene	NOUN
fnp-2819	233	36	,	,	PUNCT
fnp-2819	233	37	nor	nor	CCONJ
fnp-2819	233	38	the	the	DET
fnp-2819	233	39	epigenetic	epigenetic	ADJ
fnp-2819	233	40	drug	drug	NOUN
fnp-2819	233	41	influenced	influence	VERB
fnp-2819	233	42	its	its	PRON
fnp-2819	233	43	transcription	transcription	NOUN
fnp-2819	233	44	in	in	ADP
fnp-2819	233	45	the	the	DET
fnp-2819	233	46	slo	slo	PROPN
fnp-2819	233	47	or	or	CCONJ
fnp-2819	233	48	cns	cns	PROPN
fnp-2819	233	49	(	(	PUNCT
fnp-2819	233	50	fig	fig	NOUN
fnp-2819	233	51	.	.	PUNCT
fnp-2819	234	1	5	5	NUM
fnp-2819	234	2	,	,	PUNCT
fnp-2819	234	3	supplementary	supplementary	ADJ
fnp-2819	234	4	fig	fig	NOUN
fnp-2819	234	5	.	.	PUNCT
fnp-2819	235	1	5	5	NUM
fnp-2819	235	2	)	)	PUNCT
fnp-2819	235	3	.	.	PUNCT
fnp-2819	236	1	thus	thus	ADV
fnp-2819	236	2	,	,	PUNCT
fnp-2819	236	3	the	the	DET
fnp-2819	236	4	histone	histone	NOUN
fnp-2819	236	5	hyperacetylating	hyperacetylate	VERB
fnp-2819	236	6	drug	drug	NOUN
fnp-2819	236	7	appears	appear	VERB
fnp-2819	236	8	to	to	PART
fnp-2819	236	9	primarily	primarily	ADV
fnp-2819	236	10	target	target	VERB
fnp-2819	236	11	the	the	DET
fnp-2819	236	12	hdac11	hdac11	NOUN
fnp-2819	236	13	gene	gene	NOUN
fnp-2819	236	14	in	in	ADP
fnp-2819	236	15	the	the	DET
fnp-2819	236	16	cns	cns	NOUN
fnp-2819	236	17	of	of	ADP
fnp-2819	236	18	peae	peae	PROPN
fnp-2819	236	19	mice	mouse	NOUN
fnp-2819	236	20	and	and	CCONJ
fnp-2819	236	21	the	the	DET
fnp-2819	236	22	elucidation	elucidation	NOUN
fnp-2819	236	23	of	of	ADP
fnp-2819	236	24	the	the	DET
fnp-2819	236	25	genes	gene	NOUN
fnp-2819	236	26	that	that	PRON
fnp-2819	236	27	are	be	AUX
fnp-2819	236	28	under	under	ADP
fnp-2819	236	29	the	the	DET
fnp-2819	236	30	control	control	NOUN
fnp-2819	236	31	of	of	ADP
fnp-2819	236	32	hdac11	hdac11	NOUN
fnp-2819	236	33	may	may	AUX
fnp-2819	236	34	provide	provide	VERB
fnp-2819	236	35	novel	novel	ADJ
fnp-2819	236	36	insights	insight	NOUN
fnp-2819	236	37	into	into	ADP
fnp-2819	236	38	the	the	DET
fnp-2819	236	39	mechanisms	mechanism	NOUN
fnp-2819	236	40	of	of	ADP
fnp-2819	236	41	peae	peae	PROPN
fnp-2819	236	42	.	.	PUNCT
fnp-2819	237	1	to	to	ADP
fnp-2819	237	2	our	our	PRON
fnp-2819	237	3	surprise	surprise	NOUN
fnp-2819	237	4	,	,	PUNCT
fnp-2819	237	5	the	the	DET
fnp-2819	237	6	epigenetic	epigenetic	ADJ
fnp-2819	237	7	drug	drug	NOUN
fnp-2819	237	8	treatment	treatment	NOUN
fnp-2819	237	9	failed	fail	VERB
fnp-2819	237	10	to	to	PART
fnp-2819	237	11	validate	validate	VERB
fnp-2819	237	12	the	the	DET
fnp-2819	237	13	purported	purport	VERB
fnp-2819	237	14	roles	role	NOUN
fnp-2819	237	15	of	of	ADP
fnp-2819	237	16	the	the	DET
fnp-2819	237	17	genes	gene	NOUN
fnp-2819	237	18	critical	critical	ADJ
fnp-2819	237	19	for	for	ADP
fnp-2819	237	20	the	the	DET
fnp-2819	237	21	development	development	NOUN
fnp-2819	237	22	of	of	ADP
fnp-2819	237	23	encephalitogenic	encephalitogenic	ADJ
fnp-2819	237	24	th1	th1	NOUN
fnp-2819	237	25	and	and	CCONJ
fnp-2819	237	26	th17	th17	PROPN
fnp-2819	237	27	subsets	subset	NOUN
fnp-2819	237	28	,	,	PUNCT
fnp-2819	237	29	including	include	VERB
fnp-2819	237	30	ifng	ifng	NOUN
fnp-2819	237	31	,	,	PUNCT
fnp-2819	237	32	il12	il12	PROPN
fnp-2819	237	33	,	,	PUNCT
fnp-2819	237	34	il18	il18	PROPN
fnp-2819	237	35	,	,	PUNCT
fnp-2819	237	36	il23	il23	PROPN
fnp-2819	237	37	,	,	PUNCT
fnp-2819	237	38	tbet	tbet	NOUN
fnp-2819	237	39	,	,	PUNCT
fnp-2819	237	40	rorgt	rorgt	NOUN
fnp-2819	237	41	,	,	PUNCT
fnp-2819	237	42	gata3	gata3	PROPN
fnp-2819	237	43	,	,	PUNCT
fnp-2819	237	44	and	and	CCONJ
fnp-2819	237	45	eomes	eome	NOUN
fnp-2819	237	46	.	.	PUNCT
fnp-2819	238	1	the	the	DET
fnp-2819	238	2	disruption	disruption	NOUN
fnp-2819	238	3	of	of	ADP
fnp-2819	238	4	the	the	DET
fnp-2819	238	5	ifn	ifn	PROPN
fnp-2819	238	6	-	-	PUNCT
fnp-2819	238	7	γ	γ	NOUN
fnp-2819	238	8	gene	gene	NOUN
fnp-2819	238	9	failed	fail	VERB
fnp-2819	238	10	to	to	PART
fnp-2819	238	11	influence	influence	VERB
fnp-2819	238	12	eae	eae	PROPN
fnp-2819	238	13	development	development	PROPN
fnp-2819	238	14	(	(	PUNCT
fnp-2819	238	15	ferber	ferber	PROPN
fnp-2819	238	16	et	et	PROPN
fnp-2819	238	17	al	al	PROPN
fnp-2819	238	18	.	.	PROPN
fnp-2819	238	19	,	,	PUNCT
fnp-2819	238	20	1995	1995	NUM
fnp-2819	238	21	)	)	PUNCT
fnp-2819	238	22	,	,	PUNCT
fnp-2819	238	23	indicating	indicate	VERB
fnp-2819	238	24	a	a	DET
fnp-2819	238	25	lack	lack	NOUN
fnp-2819	238	26	of	of	ADP
fnp-2819	238	27	ifn	ifn	PROPN
fnp-2819	238	28	-	-	PUNCT
fnp-2819	238	29	γ	γ	NOUN
fnp-2819	238	30	-	-	PUNCT
fnp-2819	238	31	expressing	express	VERB
fnp-2819	238	32	cells	cell	NOUN
fnp-2819	238	33	in	in	ADP
fnp-2819	238	34	neurodegeneration	neurodegeneration	NOUN
fnp-2819	238	35	.	.	PUNCT
fnp-2819	239	1	consistently	consistently	ADV
fnp-2819	239	2	,	,	PUNCT
fnp-2819	239	3	the	the	DET
fnp-2819	239	4	reduction	reduction	NOUN
fnp-2819	239	5	of	of	ADP
fnp-2819	239	6	clinical	clinical	ADJ
fnp-2819	239	7	symptoms	symptom	NOUN
fnp-2819	239	8	by	by	ADP
fnp-2819	239	9	tsa	tsa	NOUN
fnp-2819	239	10	treatment	treatment	NOUN
fnp-2819	239	11	did	do	AUX
fnp-2819	239	12	not	not	PART
fnp-2819	239	13	accompany	accompany	VERB
fnp-2819	239	14	the	the	DET
fnp-2819	239	15	transcriptional	transcriptional	ADJ
fnp-2819	239	16	repression	repression	NOUN
fnp-2819	239	17	of	of	ADP
fnp-2819	239	18	ifn	ifn	PROPN
fnp-2819	239	19	-	-	PUNCT
fnp-2819	239	20	γ	γ	X
fnp-2819	239	21	(	(	PUNCT
fnp-2819	239	22	supplementary	supplementary	ADJ
fnp-2819	239	23	fig	fig	NOUN
fnp-2819	239	24	.	.	PUNCT
fnp-2819	240	1	1	1	NUM
fnp-2819	240	2	)	)	PUNCT
fnp-2819	240	3	.	.	PUNCT
fnp-2819	241	1	besides	besides	SCONJ
fnp-2819	241	2	,	,	PUNCT
fnp-2819	241	3	the	the	DET
fnp-2819	241	4	drug	drug	NOUN
fnp-2819	241	5	-	-	PUNCT
fnp-2819	241	6	mediated	mediate	VERB
fnp-2819	241	7	tolerance	tolerance	NOUN
fnp-2819	241	8	induction	induction	NOUN
fnp-2819	241	9	was	be	AUX
fnp-2819	241	10	evident	evident	ADJ
fnp-2819	241	11	without	without	ADP
fnp-2819	241	12	repressed	repressed	ADJ
fnp-2819	241	13	transcription	transcription	NOUN
fnp-2819	241	14	of	of	ADP
fnp-2819	241	15	tbet	tbet	NOUN
fnp-2819	241	16	,	,	PUNCT
fnp-2819	241	17	il18	il18	PROPN
fnp-2819	241	18	,	,	PUNCT
fnp-2819	241	19	and	and	CCONJ
fnp-2819	241	20	il12	il12	PROPN
fnp-2819	241	21	genes	gene	NOUN
fnp-2819	241	22	critical	critical	ADJ
fnp-2819	241	23	for	for	ADP
fnp-2819	241	24	th1	th1	PROPN
fnp-2819	241	25	cell	cell	NOUN
fnp-2819	241	26	development	development	NOUN
fnp-2819	241	27	(	(	PUNCT
fnp-2819	241	28	o'connor	o'connor	PROPN
fnp-2819	241	29	et	et	PROPN
fnp-2819	241	30	al	al	PROPN
fnp-2819	241	31	.	.	PROPN
fnp-2819	241	32	,	,	PUNCT
fnp-2819	241	33	2013	2013	NUM
fnp-2819	241	34	;	;	PUNCT
fnp-2819	241	35	lalor	lalor	NOUN
fnp-2819	241	36	et	et	PROPN
fnp-2819	241	37	al	al	PROPN
fnp-2819	241	38	.	.	PROPN
fnp-2819	241	39	,	,	PUNCT
fnp-2819	241	40	2011	2011	NUM
fnp-2819	241	41	;	;	PUNCT
fnp-2819	241	42	gran	gran	PROPN
fnp-2819	241	43	et	et	PROPN
fnp-2819	241	44	al	al	PROPN
fnp-2819	241	45	.	.	PROPN
fnp-2819	241	46	,	,	PUNCT
fnp-2819	241	47	2004	2004	NUM
fnp-2819	241	48	)	)	PUNCT
fnp-2819	241	49	(	(	PUNCT
fnp-2819	241	50	see	see	VERB
fnp-2819	241	51	supplementary	supplementary	ADJ
fnp-2819	241	52	fig	fig	NOUN
fnp-2819	241	53	.	.	PUNCT
fnp-2819	242	1	3	3	NUM
fnp-2819	242	2	)	)	PUNCT
fnp-2819	242	3	.	.	PUNCT
fnp-2819	243	1	moreover	moreover	ADV
fnp-2819	243	2	,	,	PUNCT
fnp-2819	243	3	the	the	DET
fnp-2819	243	4	transcription	transcription	NOUN
fnp-2819	243	5	of	of	ADP
fnp-2819	243	6	il23	il23	PROPN
fnp-2819	243	7	(	(	PUNCT
fnp-2819	243	8	kreymborg	kreymborg	PROPN
fnp-2819	243	9	et	et	PROPN
fnp-2819	243	10	al	al	PROPN
fnp-2819	243	11	.	.	PROPN
fnp-2819	243	12	,	,	PUNCT
fnp-2819	243	13	2007	2007	NUM
fnp-2819	243	14	;	;	PUNCT
fnp-2819	243	15	el	el	PROPN
fnp-2819	243	16	-	-	PUNCT
fnp-2819	243	17	behi	behi	PROPN
fnp-2819	243	18	et	et	NOUN
fnp-2819	243	19	al	al	PROPN
fnp-2819	243	20	.	.	PROPN
fnp-2819	243	21	,	,	PUNCT
fnp-2819	243	22	2011	2011	NUM
fnp-2819	243	23	)	)	PUNCT
fnp-2819	243	24	and	and	CCONJ
fnp-2819	243	25	rorgt	rorgt	NOUN
fnp-2819	243	26	(	(	PUNCT
fnp-2819	243	27	martinez	martinez	PROPN
fnp-2819	243	28	et	et	PROPN
fnp-2819	243	29	al	al	PROPN
fnp-2819	243	30	.	.	PROPN
fnp-2819	243	31	,	,	PUNCT
fnp-2819	243	32	2014	2014	NUM
fnp-2819	243	33	)	)	PUNCT
fnp-2819	243	34	,	,	PUNCT
fnp-2819	243	35	respectively	respectively	ADV
fnp-2819	243	36	,	,	PUNCT
fnp-2819	243	37	involved	involve	VERB
fnp-2819	243	38	in	in	ADP
fnp-2819	243	39	th17	th17	PROPN
fnp-2819	243	40	and	and	CCONJ
fnp-2819	243	41	th2	th2	PROPN
fnp-2819	243	42	cell	cell	NOUN
fnp-2819	243	43	generation	generation	NOUN
fnp-2819	243	44	was	be	AUX
fnp-2819	243	45	also	also	ADV
fnp-2819	243	46	not	not	PART
fnp-2819	243	47	diminished	diminish	VERB
fnp-2819	243	48	by	by	ADP
fnp-2819	243	49	tsa	tsa	NOUN
fnp-2819	243	50	treatment	treatment	NOUN
fnp-2819	243	51	.	.	PUNCT
fnp-2819	244	1	yet	yet	ADV
fnp-2819	244	2	,	,	PUNCT
fnp-2819	244	3	the	the	DET
fnp-2819	244	4	histone	histone	NOUN
fnp-2819	244	5	modifier	modifier	NOUN
fnp-2819	244	6	reduced	reduce	VERB
fnp-2819	244	7	the	the	DET
fnp-2819	244	8	overall	overall	ADJ
fnp-2819	244	9	numbers	number	NOUN
fnp-2819	244	10	of	of	ADP
fnp-2819	244	11	th17	th17	PROPN
fnp-2819	244	12	and	and	CCONJ
fnp-2819	244	13	th1	th1	PROPN
fnp-2819	244	14	/	/	SYM
fnp-2819	244	15	th17	th17	PROPN
fnp-2819	244	16	cells	cell	NOUN
fnp-2819	244	17	in	in	ADP
fnp-2819	244	18	the	the	DET
fnp-2819	244	19	slo	slo	PROPN
fnp-2819	244	20	(	(	PUNCT
fnp-2819	244	21	jayaraman	jayaraman	PROPN
fnp-2819	244	22	et	et	PROPN
fnp-2819	244	23	al	al	PROPN
fnp-2819	244	24	.	.	PROPN
fnp-2819	244	25	,	,	PUNCT
fnp-2819	244	26	2017	2017	NUM
fnp-2819	244	27	)	)	PUNCT
fnp-2819	244	28	.	.	PUNCT
fnp-2819	245	1	furthermore	furthermore	ADV
fnp-2819	245	2	,	,	PUNCT
fnp-2819	245	3	the	the	DET
fnp-2819	245	4	drug	drug	NOUN
fnp-2819	245	5	treatment	treatment	NOUN
fnp-2819	245	6	failed	fail	VERB
fnp-2819	245	7	to	to	PART
fnp-2819	245	8	decrease	decrease	VERB
fnp-2819	245	9	the	the	DET
fnp-2819	245	10	transcription	transcription	NOUN
fnp-2819	245	11	of	of	ADP
fnp-2819	245	12	csf2	csf2	PROPN
fnp-2819	245	13	(	(	PUNCT
fnp-2819	245	14	see	see	VERB
fnp-2819	245	15	supplementary	supplementary	ADJ
fnp-2819	245	16	fig	fig	NOUN
fnp-2819	245	17	.	.	PUNCT
fnp-2819	246	1	2	2	NUM
fnp-2819	246	2	)	)	PUNCT
fnp-2819	246	3	despite	despite	SCONJ
fnp-2819	246	4	the	the	DET
fnp-2819	246	5	diminished	diminished	ADJ
fnp-2819	246	6	numbers	number	NOUN
fnp-2819	246	7	of	of	ADP
fnp-2819	246	8	gm	gm	PROPN
fnp-2819	246	9	-	-	PUNCT
fnp-2819	246	10	csf	csf	PROPN
fnp-2819	246	11	-	-	PUNCT
fnp-2819	246	12	co	co	NOUN
fnp-2819	246	13	-	-	ADJ
fnp-2819	246	14	expressing	express	VERB
fnp-2819	246	15	th1	th1	NOUN
fnp-2819	246	16	and	and	CCONJ
fnp-2819	246	17	th17	th17	PROPN
fnp-2819	246	18	cells	cell	NOUN
fnp-2819	246	19	found	find	VERB
fnp-2819	246	20	in	in	ADP
fnp-2819	246	21	the	the	DET
fnp-2819	246	22	slo	slo	PROPN
fnp-2819	246	23	of	of	ADP
fnp-2819	246	24	tsa	tsa	PROPN
fnp-2819	246	25	-	-	PUNCT
fnp-2819	246	26	treated	treat	VERB
fnp-2819	246	27	mice	mouse	NOUN
fnp-2819	246	28	(	(	PUNCT
fnp-2819	246	29	jayaraman	jayaraman	NOUN
fnp-2819	246	30	et	et	PROPN
fnp-2819	246	31	al	al	PROPN
fnp-2819	246	32	.	.	PROPN
fnp-2819	246	33	,	,	PUNCT
fnp-2819	246	34	2017	2017	NUM
fnp-2819	246	35	)	)	PUNCT
fnp-2819	246	36	.	.	PUNCT
fnp-2819	247	1	these	these	DET
fnp-2819	247	2	data	datum	NOUN
fnp-2819	247	3	indicate	indicate	VERB
fnp-2819	247	4	that	that	SCONJ
fnp-2819	247	5	t	t	PROPN
fnp-2819	247	6	cell	cell	NOUN
fnp-2819	247	7	tolerance	tolerance	NOUN
fnp-2819	247	8	induction	induction	NOUN
fnp-2819	247	9	by	by	ADP
fnp-2819	247	10	epigenetic	epigenetic	ADJ
fnp-2819	247	11	modulation	modulation	NOUN
fnp-2819	247	12	of	of	ADP
fnp-2819	247	13	the	the	DET
fnp-2819	247	14	genome	genome	NOUN
fnp-2819	247	15	does	do	AUX
fnp-2819	247	16	not	not	PART
fnp-2819	247	17	involve	involve	VERB
fnp-2819	247	18	selective	selective	ADJ
fnp-2819	247	19	suppression	suppression	NOUN
fnp-2819	247	20	of	of	ADP
fnp-2819	247	21	genes	gene	NOUN
fnp-2819	247	22	required	require	VERB
fnp-2819	247	23	for	for	ADP
fnp-2819	247	24	the	the	DET
fnp-2819	247	25	generation	generation	NOUN
fnp-2819	247	26	of	of	ADP
fnp-2819	247	27	functionally	functionally	ADV
fnp-2819	247	28	distinct	distinct	ADJ
fnp-2819	247	29	th	th	X
fnp-2819	247	30	cell	cell	NOUN
fnp-2819	247	31	subsets	subset	NOUN
fnp-2819	247	32	.	.	PUNCT
fnp-2819	248	1	further	further	ADJ
fnp-2819	248	2	work	work	NOUN
fnp-2819	248	3	is	be	AUX
fnp-2819	248	4	necessary	necessary	ADJ
fnp-2819	248	5	to	to	PART
fnp-2819	248	6	decipher	decipher	VERB
fnp-2819	248	7	the	the	DET
fnp-2819	248	8	underlying	underlying	ADJ
fnp-2819	248	9	mechanisms	mechanism	NOUN
fnp-2819	248	10	of	of	ADP
fnp-2819	248	11	t	t	PROPN
fnp-2819	248	12	cell	cell	NOUN
fnp-2819	248	13	tolerance	tolerance	NOUN
fnp-2819	248	14	.	.	PUNCT
fnp-2819	249	1	another	another	DET
fnp-2819	249	2	deviation	deviation	NOUN
fnp-2819	249	3	from	from	ADP
fnp-2819	249	4	the	the	DET
fnp-2819	249	5	conventional	conventional	ADJ
fnp-2819	249	6	idea	idea	NOUN
fnp-2819	249	7	of	of	ADP
fnp-2819	249	8	immunoregulation	immunoregulation	NOUN
fnp-2819	249	9	is	be	AUX
fnp-2819	249	10	the	the	DET
fnp-2819	249	11	lack	lack	NOUN
fnp-2819	249	12	of	of	ADP
fnp-2819	249	13	the	the	DET
fnp-2819	249	14	modulation	modulation	NOUN
fnp-2819	249	15	of	of	ADP
fnp-2819	249	16	il10	il10	PROPN
fnp-2819	249	17	and	and	CCONJ
fnp-2819	249	18	foxp3	foxp3	NOUN
fnp-2819	249	19	both	both	CCONJ
fnp-2819	249	20	in	in	ADP
fnp-2819	249	21	the	the	DET
fnp-2819	249	22	cns	cns	PROPN
fnp-2819	249	23	and	and	CCONJ
fnp-2819	249	24	slo	slo	PROPN
fnp-2819	249	25	of	of	ADP
fnp-2819	249	26	tsa	tsa	PROPN
fnp-2819	249	27	-	-	PUNCT
fnp-2819	249	28	treated	treat	VERB
fnp-2819	249	29	mice	mouse	NOUN
fnp-2819	249	30	(	(	PUNCT
fnp-2819	249	31	supplementary	supplementary	ADJ
fnp-2819	249	32	fig	fig	NOUN
fnp-2819	249	33	.	.	PUNCT
fnp-2819	250	1	4	4	NUM
fnp-2819	250	2	)	)	PUNCT
fnp-2819	250	3	.	.	PUNCT
fnp-2819	251	1	although	although	SCONJ
fnp-2819	251	2	foxp3	foxp3	PROPN
fnp-2819	251	3	+	+	SYM
fnp-2819	251	4	t	t	PROPN
fnp-2819	251	5	regulatory	regulatory	ADJ
fnp-2819	251	6	cells	cell	NOUN
fnp-2819	251	7	are	be	AUX
fnp-2819	251	8	considered	consider	VERB
fnp-2819	251	9	critical	critical	ADJ
fnp-2819	251	10	for	for	ADP
fnp-2819	251	11	immunoregulation	immunoregulation	NOUN
fnp-2819	251	12	(	(	PUNCT
fnp-2819	251	13	hori	hori	PROPN
fnp-2819	251	14	et	et	PROPN
fnp-2819	251	15	al	al	PROPN
fnp-2819	251	16	.	.	PROPN
fnp-2819	251	17	,	,	PUNCT
fnp-2819	251	18	2003	2003	NUM
fnp-2819	251	19	)	)	PUNCT
fnp-2819	251	20	,	,	PUNCT
fnp-2819	251	21	their	their	PRON
fnp-2819	251	22	role	role	NOUN
fnp-2819	251	23	in	in	ADP
fnp-2819	251	24	eae	eae	PROPN
fnp-2819	251	25	is	be	AUX
fnp-2819	251	26	less	less	ADV
fnp-2819	251	27	compelling	compelling	ADJ
fnp-2819	251	28	(	(	PUNCT
fnp-2819	251	29	jayaraman	jayaraman	NOUN
fnp-2819	251	30	et	et	PROPN
fnp-2819	251	31	al	al	PROPN
fnp-2819	251	32	.	.	PROPN
fnp-2819	251	33	,	,	PUNCT
fnp-2819	251	34	2017	2017	NUM
fnp-2819	251	35	;	;	PUNCT
fnp-2819	251	36	danikowski	danikowski	PROPN
fnp-2819	251	37	et	et	PROPN
fnp-2819	251	38	al	al	PROPN
fnp-2819	251	39	.	.	PROPN
fnp-2819	251	40	,	,	PUNCT
fnp-2819	251	41	2017	2017	NUM
fnp-2819	251	42	;	;	PUNCT
fnp-2819	251	43	jayaraman	jayaraman	NOUN
fnp-2819	251	44	and	and	CCONJ
fnp-2819	251	45	prabhakar	prabhakar	PROPN
fnp-2819	251	46	,	,	PUNCT
fnp-2819	251	47	2019	2019	NUM
fnp-2819	251	48	)	)	PUNCT
fnp-2819	251	49	.	.	PUNCT
fnp-2819	252	1	whereas	whereas	SCONJ
fnp-2819	252	2	tsa	tsa	NOUN
fnp-2819	252	3	treatment	treatment	NOUN
fnp-2819	252	4	increased	increase	VERB
fnp-2819	252	5	foxp3	foxp3	NOUN
fnp-2819	252	6	expression	expression	NOUN
fnp-2819	252	7	and	and	CCONJ
fnp-2819	252	8	promoted	promote	VERB
fnp-2819	252	9	t	t	PROPN
fnp-2819	252	10	regulatory	regulatory	ADJ
fnp-2819	252	11	cell	cell	NOUN
fnp-2819	252	12	function	function	NOUN
fnp-2819	252	13	via	via	ADP
fnp-2819	252	14	the	the	DET
fnp-2819	252	15	upregulation	upregulation	NOUN
fnp-2819	252	16	of	of	ADP
fnp-2819	252	17	hdac9	hdac9	NOUN
fnp-2819	252	18	in	in	ADP
fnp-2819	252	19	a	a	DET
fnp-2819	252	20	different	different	ADJ
fnp-2819	252	21	experimental	experimental	ADJ
fnp-2819	252	22	model	model	NOUN
fnp-2819	252	23	(	(	PUNCT
fnp-2819	252	24	tao	tao	PROPN
fnp-2819	252	25	et	et	PROPN
fnp-2819	252	26	al	al	PROPN
fnp-2819	252	27	.	.	PROPN
fnp-2819	252	28	,	,	PUNCT
fnp-2819	252	29	2007	2007	NUM
fnp-2819	252	30	)	)	PUNCT
fnp-2819	252	31	,	,	PUNCT
fnp-2819	252	32	our	our	PRON
fnp-2819	252	33	results	result	NOUN
fnp-2819	252	34	contradict	contradict	VERB
fnp-2819	252	35	these	these	DET
fnp-2819	252	36	findings	finding	NOUN
fnp-2819	252	37	.	.	PUNCT
fnp-2819	253	1	it	it	PRON
fnp-2819	253	2	is	be	AUX
fnp-2819	253	3	also	also	ADV
fnp-2819	253	4	noteworthy	noteworthy	ADJ
fnp-2819	253	5	that	that	SCONJ
fnp-2819	253	6	tsa	tsa	NOUN
fnp-2819	253	7	treatment	treatment	NOUN
fnp-2819	253	8	downregulated	downregulate	VERB
fnp-2819	253	9	foxp3	foxp3	NOUN
fnp-2819	253	10	expression	expression	NOUN
fnp-2819	253	11	and	and	CCONJ
fnp-2819	253	12	lowered	lower	VERB
fnp-2819	253	13	the	the	DET
fnp-2819	253	14	numbers	number	NOUN
fnp-2819	253	15	of	of	ADP
fnp-2819	253	16	cd4+cd25	cd4+cd25	NOUN
fnp-2819	253	17	+	+	PROPN
fnp-2819	253	18	t	t	NOUN
fnp-2819	253	19	regulatory	regulatory	ADJ
fnp-2819	253	20	cells	cell	NOUN
fnp-2819	253	21	(	(	PUNCT
fnp-2819	253	22	liu	liu	PROPN
fnp-2819	253	23	et	et	PROPN
fnp-2819	253	24	al	al	PROPN
fnp-2819	253	25	.	.	PROPN
fnp-2819	253	26	,	,	PUNCT
fnp-2819	253	27	2010	2010	NUM
fnp-2819	253	28	)	)	PUNCT
fnp-2819	253	29	.	.	PUNCT
fnp-2819	254	1	nevertheless	nevertheless	ADV
fnp-2819	254	2	,	,	PUNCT
fnp-2819	254	3	our	our	PRON
fnp-2819	254	4	data	datum	NOUN
fnp-2819	254	5	indicate	indicate	VERB
fnp-2819	254	6	that	that	SCONJ
fnp-2819	254	7	tsa	tsa	NOUN
fnp-2819	254	8	-	-	PUNCT
fnp-2819	254	9	mediated	mediate	VERB
fnp-2819	254	10	protection	protection	NOUN
fnp-2819	254	11	from	from	ADP
fnp-2819	254	12	peae	peae	PROPN
fnp-2819	254	13	in	in	ADP
fnp-2819	254	14	autoimmune	autoimmune	ADJ
fnp-2819	254	15	-	-	PUNCT
fnp-2819	254	16	prone	prone	ADJ
fnp-2819	254	17	nod	nod	NOUN
fnp-2819	254	18	mice	mouse	NOUN
fnp-2819	254	19	is	be	AUX
fnp-2819	254	20	independent	independent	ADJ
fnp-2819	254	21	of	of	ADP
fnp-2819	254	22	il-10	il-10	PRON
fnp-2819	254	23	and	and	CCONJ
fnp-2819	254	24	foxp3	foxp3	PROPN
fnp-2819	254	25	+	+	SYM
fnp-2819	254	26	t	t	NOUN
fnp-2819	254	27	regulatory	regulatory	ADJ
fnp-2819	254	28	cells	cell	NOUN
fnp-2819	254	29	.	.	PUNCT
fnp-2819	255	1	differential	differential	ADJ
fnp-2819	255	2	rna	rna	PROPN
fnp-2819	255	3	display	display	NOUN
fnp-2819	255	4	(	(	PUNCT
fnp-2819	255	5	van	van	PROPN
fnp-2819	255	6	lint	lint	NOUN
fnp-2819	255	7	et	et	PROPN
fnp-2819	255	8	al	al	PROPN
fnp-2819	255	9	.	.	PROPN
fnp-2819	255	10	,	,	PUNCT
fnp-2819	255	11	1996	1996	NUM
fnp-2819	255	12	)	)	PUNCT
fnp-2819	255	13	and	and	CCONJ
fnp-2819	255	14	microarray	microarray	VERB
fnp-2819	255	15	analysis	analysis	NOUN
fnp-2819	255	16	of	of	ADP
fnp-2819	255	17	gene	gene	NOUN
fnp-2819	255	18	expression	expression	NOUN
fnp-2819	255	19	(	(	PUNCT
fnp-2819	255	20	jayaraman	jayaraman	NOUN
fnp-2819	255	21	et	et	PROPN
fnp-2819	255	22	al	al	PROPN
fnp-2819	255	23	.	.	PROPN
fnp-2819	255	24	,	,	PUNCT
fnp-2819	255	25	2013	2013	NUM
fnp-2819	255	26	)	)	PUNCT
fnp-2819	255	27	indicated	indicate	VERB
fnp-2819	255	28	that	that	SCONJ
fnp-2819	255	29	histone	histone	NOUN
fnp-2819	255	30	hyperacetylation	hyperacetylation	NOUN
fnp-2819	255	31	by	by	ADP
fnp-2819	255	32	tsa	tsa	NOUN
fnp-2819	255	33	treatment	treatment	NOUN
fnp-2819	255	34	could	could	AUX
fnp-2819	255	35	have	have	VERB
fnp-2819	255	36	positive	positive	ADJ
fnp-2819	255	37	,	,	PUNCT
fnp-2819	255	38	negative	negative	ADJ
fnp-2819	255	39	,	,	PUNCT
fnp-2819	255	40	or	or	CCONJ
fnp-2819	255	41	no	no	DET
fnp-2819	255	42	effect	effect	NOUN
fnp-2819	255	43	on	on	ADP
fnp-2819	255	44	gene	gene	NOUN
fnp-2819	255	45	transcription	transcription	NOUN
fnp-2819	255	46	.	.	PUNCT
fnp-2819	256	1	our	our	PRON
fnp-2819	256	2	qrt	qrt	ADJ
fnp-2819	256	3	-	-	PUNCT
fnp-2819	256	4	pcr	pcr	ADJ
fnp-2819	256	5	analysis	analysis	NOUN
fnp-2819	256	6	showed	show	VERB
fnp-2819	256	7	that	that	SCONJ
fnp-2819	256	8	out	out	ADP
fnp-2819	256	9	of	of	ADP
fnp-2819	256	10	41	41	NUM
fnp-2819	256	11	genes	gene	NOUN
fnp-2819	256	12	interrogated	interrogate	VERB
fnp-2819	256	13	,	,	PUNCT
fnp-2819	256	14	11	11	NUM
fnp-2819	256	15	were	be	AUX
fnp-2819	256	16	consistently	consistently	ADV
fnp-2819	256	17	downregulated	downregulate	VERB
fnp-2819	256	18	over	over	ADP
fnp-2819	256	19	multiple	multiple	ADJ
fnp-2819	256	20	time	time	NOUN
fnp-2819	256	21	points	point	NOUN
fnp-2819	256	22	following	follow	VERB
fnp-2819	256	23	tsa	tsa	NOUN
fnp-2819	256	24	treatment	treatment	NOUN
fnp-2819	256	25	(	(	PUNCT
fnp-2819	256	26	vide	vide	NOUN
fnp-2819	256	27	supra	supra	PROPN
fnp-2819	256	28	)	)	PUNCT
fnp-2819	256	29	.	.	PUNCT
fnp-2819	257	1	rarely	rarely	ADV
fnp-2819	257	2	,	,	PUNCT
fnp-2819	257	3	tsa	tsa	NOUN
fnp-2819	257	4	treatment	treatment	NOUN
fnp-2819	257	5	can	can	AUX
fnp-2819	257	6	also	also	ADV
fnp-2819	257	7	increase	increase	VERB
fnp-2819	257	8	the	the	DET
fnp-2819	257	9	transcription	transcription	NOUN
fnp-2819	257	10	of	of	ADP
fnp-2819	257	11	genes	gene	NOUN
fnp-2819	257	12	due	due	ADP
fnp-2819	257	13	to	to	ADP
fnp-2819	257	14	the	the	DET
fnp-2819	257	15	transcriptional	transcriptional	ADJ
fnp-2819	257	16	suppression	suppression	NOUN
fnp-2819	257	17	of	of	ADP
fnp-2819	257	18	repressor	repressor	NOUN
fnp-2819	257	19	complexes	complex	NOUN
fnp-2819	257	20	that	that	PRON
fnp-2819	257	21	control	control	VERB
fnp-2819	257	22	gene	gene	NOUN
fnp-2819	257	23	expression	expression	NOUN
fnp-2819	257	24	.	.	PUNCT
fnp-2819	258	1	thus	thus	ADV
fnp-2819	258	2	,	,	PUNCT
fnp-2819	258	3	dec1	dec1	PROPN
fnp-2819	258	4	was	be	AUX
fnp-2819	258	5	selectively	selectively	ADV
fnp-2819	258	6	upregulated	upregulate	VERB
fnp-2819	258	7	in	in	ADP
fnp-2819	258	8	the	the	DET
fnp-2819	258	9	cns	cns	NOUN
fnp-2819	258	10	by	by	ADP
fnp-2819	258	11	the	the	DET
fnp-2819	258	12	histone	histone	NOUN
fnp-2819	258	13	modifier	modifier	NOUN
fnp-2819	258	14	,	,	PUNCT
fnp-2819	258	15	suggesting	suggest	VERB
fnp-2819	258	16	a	a	DET
fnp-2819	258	17	role	role	NOUN
fnp-2819	258	18	in	in	ADP
fnp-2819	258	19	protection	protection	NOUN
fnp-2819	258	20	against	against	ADP
fnp-2819	258	21	peae	peae	PROPN
fnp-2819	258	22	(	(	PUNCT
fnp-2819	258	23	fig	fig	NOUN
fnp-2819	258	24	.	.	PUNCT
fnp-2819	259	1	2h	2h	NUM
fnp-2819	259	2	)	)	PUNCT
fnp-2819	259	3	.	.	PUNCT
fnp-2819	260	1	this	this	PRON
fnp-2819	260	2	is	be	AUX
fnp-2819	260	3	in	in	ADP
fnp-2819	260	4	contrast	contrast	NOUN
fnp-2819	260	5	to	to	ADP
fnp-2819	260	6	the	the	DET
fnp-2819	260	7	finding	finding	NOUN
fnp-2819	260	8	that	that	SCONJ
fnp-2819	260	9	the	the	DET
fnp-2819	260	10	genetic	genetic	ADJ
fnp-2819	260	11	deletion	deletion	NOUN
fnp-2819	260	12	of	of	ADP
fnp-2819	260	13	dec1	dec1	PROPN
fnp-2819	260	14	(	(	PUNCT
fnp-2819	260	15	bhlhe40-/-	bhlhe40-/-	NOUN
fnp-2819	260	16	)	)	PUNCT
fnp-2819	260	17	afforded	afford	VERB
fnp-2819	260	18	resistance	resistance	NOUN
fnp-2819	260	19	to	to	ADP
fnp-2819	260	20	eae	eae	PROPN
fnp-2819	260	21	induction	induction	NOUN
fnp-2819	260	22	(	(	PUNCT
fnp-2819	260	23	lin	lin	PROPN
fnp-2819	260	24	et	et	PROPN
fnp-2819	260	25	al	al	PROPN
fnp-2819	260	26	.	.	PROPN
fnp-2819	260	27	,	,	PUNCT
fnp-2819	260	28	2016	2016	NUM
fnp-2819	260	29	)	)	PUNCT
fnp-2819	260	30	.	.	PUNCT
fnp-2819	261	1	like	like	ADP
fnp-2819	261	2	an	an	DET
fnp-2819	261	3	earlier	early	ADJ
fnp-2819	261	4	study	study	NOUN
fnp-2819	261	5	(	(	PUNCT
fnp-2819	261	6	hidaka	hidaka	X
fnp-2819	261	7	et	et	PROPN
fnp-2819	261	8	al	al	PROPN
fnp-2819	261	9	.	.	PROPN
fnp-2819	261	10	,	,	PUNCT
fnp-2819	261	11	2014	2014	NUM
fnp-2819	261	12	)	)	PUNCT
fnp-2819	261	13	,	,	PUNCT
fnp-2819	261	14	we	we	PRON
fnp-2819	261	15	found	find	VERB
fnp-2819	261	16	that	that	SCONJ
fnp-2819	261	17	the	the	DET
fnp-2819	261	18	expression	expression	NOUN
fnp-2819	261	19	of	of	ADP
fnp-2819	261	20	the	the	DET
fnp-2819	261	21	ccl2	ccl2	NOUN
fnp-2819	261	22	gene	gene	NOUN
fnp-2819	261	23	was	be	AUX
fnp-2819	261	24	dramatically	dramatically	ADV
fnp-2819	261	25	increased	increase	VERB
fnp-2819	261	26	in	in	ADP
fnp-2819	261	27	the	the	DET
fnp-2819	261	28	slo	slo	PROPN
fnp-2819	261	29	of	of	ADP
fnp-2819	261	30	mog35	mog35	PROPN
fnp-2819	261	31	-	-	PUNCT
fnp-2819	261	32	55	55	NUM
fnp-2819	261	33	immunized	immunize	VERB
fnp-2819	261	34	nod	nod	NOUN
fnp-2819	261	35	mice	mouse	NOUN
fnp-2819	261	36	(	(	PUNCT
fnp-2819	261	37	fig	fig	NOUN
fnp-2819	261	38	.	.	PUNCT
fnp-2819	262	1	4	4	NUM
fnp-2819	262	2	)	)	PUNCT
fnp-2819	262	3	.	.	PUNCT
fnp-2819	263	1	however	however	ADV
fnp-2819	263	2	,	,	PUNCT
fnp-2819	263	3	tsa	tsa	NOUN
fnp-2819	263	4	treatment	treatment	NOUN
fnp-2819	263	5	failed	fail	VERB
fnp-2819	263	6	to	to	PART
fnp-2819	263	7	influence	influence	VERB
fnp-2819	263	8	its	its	PRON
fnp-2819	263	9	expression	expression	NOUN
fnp-2819	263	10	.	.	PUNCT
fnp-2819	264	1	moreover	moreover	ADV
fnp-2819	264	2	,	,	PUNCT
fnp-2819	264	3	there	there	PRON
fnp-2819	264	4	is	be	VERB
fnp-2819	264	5	a	a	DET
fnp-2819	264	6	disconnect	disconnect	NOUN
fnp-2819	264	7	between	between	ADP
fnp-2819	264	8	the	the	DET
fnp-2819	264	9	ccl2	ccl2	PROPN
fnp-2819	264	10	mrna	mrna	PROPN
fnp-2819	264	11	expression	expression	NOUN
fnp-2819	264	12	in	in	ADP
fnp-2819	264	13	the	the	DET
fnp-2819	264	14	slo	slo	PROPN
fnp-2819	264	15	and	and	CCONJ
fnp-2819	264	16	the	the	DET
fnp-2819	264	17	release	release	NOUN
fnp-2819	264	18	of	of	ADP
fnp-2819	264	19	the	the	DET
fnp-2819	264	20	ccl2	ccl2	NOUN
fnp-2819	264	21	protein	protein	NOUN
fnp-2819	264	22	into	into	ADP
fnp-2819	264	23	the	the	DET
fnp-2819	264	24	peripheral	peripheral	ADJ
fnp-2819	264	25	blood	blood	NOUN
fnp-2819	264	26	.	.	PUNCT
fnp-2819	265	1	it	it	PRON
fnp-2819	265	2	has	have	AUX
fnp-2819	265	3	been	be	AUX
fnp-2819	265	4	proposed	propose	VERB
fnp-2819	265	5	that	that	SCONJ
fnp-2819	265	6	ccl2	ccl2	PROPN
fnp-2819	265	7	expressed	express	VERB
fnp-2819	265	8	by	by	ADP
fnp-2819	265	9	the	the	DET
fnp-2819	265	10	cns	cns	PROPN
fnp-2819	265	11	resident	resident	NOUN
fnp-2819	265	12	astrocytes	astrocyte	NOUN
fnp-2819	265	13	may	may	AUX
fnp-2819	265	14	serve	serve	VERB
fnp-2819	265	15	as	as	ADP
fnp-2819	265	16	a	a	DET
fnp-2819	265	17	target	target	NOUN
fnp-2819	265	18	for	for	ADP
fnp-2819	265	19	ms	ms	PROPN
fnp-2819	265	20	treatment	treatment	PROPN
fnp-2819	265	21	(	(	PUNCT
fnp-2819	265	22	mahad	mahad	PROPN
fnp-2819	265	23	and	and	CCONJ
fnp-2819	265	24	ronsohoff	ronsohoff	NOUN
fnp-2819	265	25	,	,	PUNCT
fnp-2819	265	26	2003	2003	NUM
fnp-2819	265	27	;	;	PUNCT
fnp-2819	266	1	moreno	moreno	PROPN
fnp-2819	266	2	et	et	PROPN
fnp-2819	266	3	al	al	PROPN
fnp-2819	266	4	.	.	PROPN
fnp-2819	266	5	,	,	PUNCT
fnp-2819	266	6	2014	2014	NUM
fnp-2819	266	7	)	)	PUNCT
fnp-2819	266	8	.	.	PUNCT
fnp-2819	267	1	however	however	ADV
fnp-2819	267	2	,	,	PUNCT
fnp-2819	267	3	ccl2	ccl2	PROPN
fnp-2819	267	4	and	and	CCONJ
fnp-2819	267	5	ccr2	ccr2	PROPN
fnp-2819	267	6	genes	gene	NOUN
fnp-2819	267	7	are	be	AUX
fnp-2819	267	8	refractory	refractory	NOUN
fnp-2819	267	9	to	to	ADP
fnp-2819	267	10	histone	histone	NOUN
fnp-2819	267	11	hyperacetylation	hyperacetylation	NOUN
fnp-2819	267	12	,	,	PUNCT
fnp-2819	267	13	and	and	CCONJ
fnp-2819	267	14	therefore	therefore	ADV
fnp-2819	267	15	do	do	AUX
fnp-2819	267	16	not	not	PART
fnp-2819	267	17	appear	appear	VERB
fnp-2819	267	18	to	to	PART
fnp-2819	267	19	be	be	AUX
fnp-2819	267	20	essential	essential	ADJ
fnp-2819	267	21	for	for	ADP
fnp-2819	267	22	peae	peae	ADJ
fnp-2819	267	23	induction	induction	NOUN
fnp-2819	267	24	and	and	CCONJ
fnp-2819	267	25	manifestation	manifestation	NOUN
fnp-2819	267	26	.	.	PUNCT
fnp-2819	268	1	this	this	DET
fnp-2819	268	2	observation	observation	NOUN
fnp-2819	268	3	does	do	AUX
fnp-2819	268	4	not	not	PART
fnp-2819	268	5	come	come	VERB
fnp-2819	268	6	as	as	ADP
fnp-2819	268	7	a	a	DET
fnp-2819	268	8	surprise	surprise	NOUN
fnp-2819	268	9	since	since	SCONJ
fnp-2819	268	10	the	the	DET
fnp-2819	268	11	level	level	NOUN
fnp-2819	268	12	of	of	ADP
fnp-2819	268	13	ccl2	ccl2	NOUN
fnp-2819	268	14	was	be	AUX
fnp-2819	268	15	also	also	ADV
fnp-2819	268	16	reported	report	VERB
fnp-2819	268	17	to	to	PART
fnp-2819	268	18	be	be	AUX
fnp-2819	268	19	lower	low	ADJ
fnp-2819	268	20	in	in	ADP
fnp-2819	268	21	relapsing	relapse	VERB
fnp-2819	268	22	-	-	PUNCT
fnp-2819	268	23	remitting	remit	VERB
fnp-2819	268	24	ms	ms	ADJ
fnp-2819	268	25	patients	patient	NOUN
fnp-2819	268	26	(	(	PUNCT
fnp-2819	268	27	narikawa	narikawa	X
fnp-2819	268	28	et	et	NOUN
fnp-2819	268	29	al	al	PROPN
fnp-2819	268	30	.	.	PROPN
fnp-2819	268	31	,	,	PUNCT
fnp-2819	268	32	2004	2004	NUM
fnp-2819	268	33	;	;	PUNCT
fnp-2819	269	1	moreira	moreira	PROPN
fnp-2819	269	2	et	et	PROPN
fnp-2819	269	3	al	al	PROPN
fnp-2819	269	4	.	.	PROPN
fnp-2819	269	5	,	,	PUNCT
fnp-2819	269	6	2006	2006	NUM
fnp-2819	269	7	)	)	PUNCT
fnp-2819	269	8	,	,	PUNCT
fnp-2819	269	9	and	and	CCONJ
fnp-2819	269	10	the	the	DET
fnp-2819	269	11	ifn	ifn	PROPN
fnp-2819	269	12	-	-	PUNCT
fnp-2819	269	13	beta	beta	NOUN
fnp-2819	269	14	1a	1a	X
fnp-2819	269	15	therapy	therapy	NOUN
fnp-2819	269	16	reduced	reduce	VERB
fnp-2819	269	17	relapses	relapse	NOUN
fnp-2819	269	18	while	while	SCONJ
fnp-2819	269	19	increasing	increase	VERB
fnp-2819	269	20	the	the	DET
fnp-2819	269	21	level	level	NOUN
fnp-2819	269	22	of	of	ADP
fnp-2819	269	23	ccl2	ccl2	NOUN
fnp-2819	269	24	in	in	ADP
fnp-2819	269	25	ms	ms	PROPN
fnp-2819	269	26	patients	patient	NOUN
fnp-2819	269	27	(	(	PUNCT
fnp-2819	269	28	szczuciński	szczuciński	NOUN
fnp-2819	269	29	and	and	CCONJ
fnp-2819	269	30	losy	losy	NOUN
fnp-2819	269	31	,	,	PUNCT
fnp-2819	269	32	2004	2004	NUM
fnp-2819	269	33	)	)	PUNCT
fnp-2819	269	34	.	.	PUNCT
fnp-2819	270	1	thus	thus	ADV
fnp-2819	270	2	,	,	PUNCT
fnp-2819	270	3	these	these	DET
fnp-2819	270	4	data	datum	NOUN
fnp-2819	270	5	do	do	AUX
fnp-2819	270	6	not	not	PART
fnp-2819	270	7	support	support	VERB
fnp-2819	270	8	the	the	DET
fnp-2819	270	9	hypothesis	hypothesis	NOUN
fnp-2819	270	10	that	that	PRON
fnp-2819	270	11	the	the	DET
fnp-2819	270	12	ccl2	ccl2	NOUN
fnp-2819	270	13	:	:	PUNCT
fnp-2819	270	14	ccr2	ccr2	NOUN
fnp-2819	270	15	system	system	NOUN
fnp-2819	270	16	may	may	AUX
fnp-2819	270	17	impact	impact	VERB
fnp-2819	270	18	neurodegeneration	neurodegeneration	NOUN
fnp-2819	270	19	.	.	PUNCT
fnp-2819	271	1	it	it	PRON
fnp-2819	271	2	is	be	AUX
fnp-2819	271	3	noteworthy	noteworthy	ADJ
fnp-2819	271	4	that	that	SCONJ
fnp-2819	271	5	tsa	tsa	NOUN
fnp-2819	271	6	administration	administration	NOUN
fnp-2819	271	7	induced	induce	VERB
fnp-2819	271	8	neuroprotection	neuroprotection	NOUN
fnp-2819	271	9	and	and	CCONJ
fnp-2819	271	10	gene	gene	NOUN
fnp-2819	271	11	regulation	regulation	NOUN
fnp-2819	271	12	similarly	similarly	ADV
fnp-2819	271	13	in	in	ADP
fnp-2819	271	14	prediabetic	prediabetic	ADJ
fnp-2819	271	15	,	,	PUNCT
fnp-2819	271	16	9	9	NUM
fnp-2819	271	17	-	-	SYM
fnp-2819	271	18	13	13	NUM
fnp-2819	271	19	weeks	week	NOUN
fnp-2819	271	20	old	old	ADJ
fnp-2819	271	21	,	,	PUNCT
fnp-2819	271	22	and	and	CCONJ
fnp-2819	271	23	aged	aged	ADJ
fnp-2819	271	24	(	(	PUNCT
fnp-2819	271	25	17	17	NUM
fnp-2819	271	26	-	-	PUNCT
fnp-2819	271	27	weeks	week	NOUN
fnp-2819	271	28	old	old	ADJ
fnp-2819	271	29	)	)	PUNCT
fnp-2819	271	30	mice	mouse	NOUN
fnp-2819	271	31	(	(	PUNCT
fnp-2819	271	32	jayaraman	jayaraman	NOUN
fnp-2819	271	33	et	et	PROPN
fnp-2819	271	34	al	al	PROPN
fnp-2819	271	35	.	.	PROPN
fnp-2819	271	36	,	,	PUNCT
fnp-2819	271	37	2017	2017	NUM
fnp-2819	271	38	;	;	PUNCT
fnp-2819	271	39	fig	fig	NOUN
fnp-2819	271	40	.	.	PUNCT
fnp-2819	272	1	1	1	NUM
fnp-2819	272	2	-	-	SYM
fnp-2819	272	3	5	5	NUM
fnp-2819	272	4	)	)	PUNCT
fnp-2819	272	5	.	.	PUNCT
fnp-2819	273	1	the	the	DET
fnp-2819	273	2	administration	administration	NOUN
fnp-2819	273	3	of	of	ADP
fnp-2819	273	4	the	the	DET
fnp-2819	273	5	epigenetic	epigenetic	ADJ
fnp-2819	273	6	drug	drug	NOUN
fnp-2819	273	7	for	for	ADP
fnp-2819	273	8	one	one	NUM
fnp-2819	273	9	to	to	PART
fnp-2819	273	10	six	six	NUM
fnp-2819	273	11	weeks	week	NOUN
fnp-2819	273	12	bestowed	bestow	VERB
fnp-2819	273	13	comparable	comparable	ADJ
fnp-2819	273	14	neuroprotection	neuroprotection	NOUN
fnp-2819	273	15	and	and	CCONJ
fnp-2819	273	16	gene	gene	NOUN
fnp-2819	273	17	regulation	regulation	NOUN
fnp-2819	273	18	irrespective	irrespective	ADV
fnp-2819	273	19	of	of	ADP
fnp-2819	273	20	the	the	DET
fnp-2819	273	21	age	age	NOUN
fnp-2819	273	22	of	of	ADP
fnp-2819	273	23	the	the	DET
fnp-2819	273	24	mice	mouse	NOUN
fnp-2819	273	25	.	.	PUNCT
fnp-2819	274	1	circumstantial	circumstantial	ADJ
fnp-2819	274	2	evidence	evidence	NOUN
fnp-2819	274	3	also	also	ADV
fnp-2819	274	4	indicates	indicate	VERB
fnp-2819	274	5	the	the	DET
fnp-2819	274	6	lack	lack	NOUN
fnp-2819	274	7	of	of	ADP
fnp-2819	274	8	influence	influence	NOUN
fnp-2819	274	9	of	of	ADP
fnp-2819	274	10	diabetes	diabetes	NOUN
fnp-2819	274	11	on	on	ADP
fnp-2819	274	12	peae	peae	ADJ
fnp-2819	274	13	induction	induction	NOUN
fnp-2819	274	14	.	.	PUNCT
fnp-2819	275	1	as	as	SCONJ
fnp-2819	275	2	expected	expect	VERB
fnp-2819	275	3	,	,	PUNCT
fnp-2819	275	4	the	the	DET
fnp-2819	275	5	prediabetic	prediabetic	ADJ
fnp-2819	275	6	(	(	PUNCT
fnp-2819	275	7	9	9	NUM
fnp-2819	275	8	-	-	SYM
fnp-2819	275	9	13	13	NUM
fnp-2819	275	10	-	-	PUNCT
fnp-2819	275	11	weeks	week	NOUN
fnp-2819	275	12	old	old	ADJ
fnp-2819	275	13	)	)	PUNCT
fnp-2819	275	14	mice	mouse	NOUN
fnp-2819	275	15	were	be	AUX
fnp-2819	275	16	normoglycemic	normoglycemic	ADJ
fnp-2819	275	17	at	at	ADP
fnp-2819	275	18	the	the	DET
fnp-2819	275	19	time	time	NOUN
fnp-2819	275	20	of	of	ADP
fnp-2819	275	21	immunization	immunization	NOUN
fnp-2819	275	22	with	with	ADP
fnp-2819	275	23	mog35	mog35	NOUN
fnp-2819	275	24	-	-	PUNCT
fnp-2819	275	25	55	55	NUM
fnp-2819	275	26	and	and	CCONJ
fnp-2819	275	27	remained	remain	VERB
fnp-2819	275	28	non	non	ADJ
fnp-2819	275	29	-	-	ADJ
fnp-2819	275	30	diabetic	diabetic	ADJ
fnp-2819	275	31	as	as	ADV
fnp-2819	275	32	long	long	ADV
fnp-2819	275	33	as	as	ADP
fnp-2819	275	34	27	27	NUM
fnp-2819	275	35	weeks	week	NOUN
fnp-2819	275	36	of	of	ADP
fnp-2819	275	37	age	age	NOUN
fnp-2819	275	38	.	.	PUNCT
fnp-2819	276	1	the	the	DET
fnp-2819	276	2	lack	lack	NOUN
fnp-2819	276	3	of	of	ADP
fnp-2819	276	4	diabetes	diabetes	NOUN
fnp-2819	276	5	in	in	ADP
fnp-2819	276	6	immunized	immunize	VERB
fnp-2819	276	7	mice	mouse	NOUN
fnp-2819	276	8	could	could	AUX
fnp-2819	276	9	be	be	AUX
fnp-2819	276	10	due	due	ADJ
fnp-2819	276	11	to	to	ADP
fnp-2819	276	12	the	the	DET
fnp-2819	276	13	action	action	NOUN
fnp-2819	276	14	of	of	ADP
fnp-2819	276	15	the	the	DET
fnp-2819	276	16	microbial	microbial	ADJ
fnp-2819	276	17	products	product	NOUN
fnp-2819	276	18	present	present	ADJ
fnp-2819	276	19	in	in	ADP
fnp-2819	276	20	the	the	DET
fnp-2819	276	21	complete	complete	ADJ
fnp-2819	276	22	freund	freund	PROPN
fnp-2819	276	23	’s	’s	PART
fnp-2819	276	24	adjuvant	adjuvant	NOUN
fnp-2819	276	25	.	.	PUNCT
fnp-2819	277	1	in	in	ADP
fnp-2819	277	2	fact	fact	NOUN
fnp-2819	277	3	,	,	PUNCT
fnp-2819	277	4	we	we	PRON
fnp-2819	277	5	have	have	AUX
fnp-2819	277	6	shown	show	VERB
fnp-2819	277	7	that	that	SCONJ
fnp-2819	277	8	the	the	DET
fnp-2819	277	9	administration	administration	NOUN
fnp-2819	277	10	of	of	ADP
fnp-2819	277	11	complete	complete	PROPN
fnp-2819	277	12	freund	freund	PROPN
fnp-2819	277	13	’s	’s	PART
fnp-2819	277	14	adjuvant	adjuvant	NOUN
fnp-2819	277	15	alone	alone	ADV
fnp-2819	277	16	is	be	AUX
fnp-2819	277	17	sufficient	sufficient	ADJ
fnp-2819	277	18	to	to	PART
fnp-2819	277	19	prevent	prevent	VERB
fnp-2819	277	20	prediabetic	prediabetic	ADJ
fnp-2819	277	21	nod	nod	NOUN
fnp-2819	277	22	mice	mouse	NOUN
fnp-2819	277	23	from	from	ADP
fnp-2819	277	24	developing	develop	VERB
fnp-2819	277	25	overt	overt	ADJ
fnp-2819	277	26	diabetes	diabetes	NOUN
fnp-2819	277	27	(	(	PUNCT
fnp-2819	277	28	jayaraman	jayaraman	NOUN
fnp-2819	277	29	and	and	CCONJ
fnp-2819	277	30	jayaraman	jayaraman	NOUN
fnp-2819	277	31	,	,	PUNCT
fnp-2819	277	32	2018	2018	NUM
fnp-2819	277	33	)	)	PUNCT
fnp-2819	277	34	.	.	PUNCT
fnp-2819	278	1	although	although	SCONJ
fnp-2819	278	2	a	a	DET
fnp-2819	278	3	fraction	fraction	NOUN
fnp-2819	278	4	of	of	ADP
fnp-2819	278	5	the	the	DET
fnp-2819	278	6	older	old	ADJ
fnp-2819	278	7	(	(	PUNCT
fnp-2819	278	8	17	17	NUM
fnp-2819	278	9	weeks	week	NOUN
fnp-2819	278	10	old	old	ADJ
fnp-2819	278	11	)	)	PUNCT
fnp-2819	278	12	mice	mouse	NOUN
fnp-2819	278	13	developed	develop	VERB
fnp-2819	278	14	diabetes	diabete	NOUN
fnp-2819	278	15	,	,	PUNCT
fnp-2819	278	16	it	it	PRON
fnp-2819	278	17	did	do	AUX
fnp-2819	278	18	not	not	PART
fnp-2819	278	19	impede	impede	VERB
fnp-2819	278	20	peae	peae	ADJ
fnp-2819	278	21	induction	induction	NOUN
fnp-2819	278	22	(	(	PUNCT
fnp-2819	278	23	fig	fig	NOUN
fnp-2819	278	24	.	.	PUNCT
fnp-2819	279	1	1b	1b	NUM
fnp-2819	279	2	-	-	PUNCT
fnp-2819	279	3	c	c	NOUN
fnp-2819	279	4	)	)	PUNCT
fnp-2819	279	5	nor	nor	CCONJ
fnp-2819	279	6	the	the	DET
fnp-2819	279	7	modulation	modulation	NOUN
fnp-2819	279	8	of	of	ADP
fnp-2819	279	9	gene	gene	NOUN
fnp-2819	279	10	expression	expression	NOUN
fnp-2819	279	11	in	in	ADP
fnp-2819	279	12	response	response	NOUN
fnp-2819	279	13	to	to	ADP
fnp-2819	279	14	tsa	tsa	NOUN
fnp-2819	279	15	treatment	treatment	NOUN
fnp-2819	279	16	(	(	PUNCT
fnp-2819	279	17	fig	fig	NOUN
fnp-2819	279	18	.	.	PUNCT
fnp-2819	280	1	2	2	NUM
fnp-2819	280	2	-	-	SYM
fnp-2819	280	3	5	5	NUM
fnp-2819	280	4	)	)	PUNCT
fnp-2819	280	5	.	.	PUNCT
fnp-2819	281	1	collectively	collectively	ADV
fnp-2819	281	2	,	,	PUNCT
fnp-2819	281	3	these	these	DET
fnp-2819	281	4	data	datum	NOUN
fnp-2819	281	5	demonstrate	demonstrate	VERB
fnp-2819	281	6	that	that	SCONJ
fnp-2819	281	7	the	the	DET
fnp-2819	281	8	induction	induction	NOUN
fnp-2819	281	9	of	of	ADP
fnp-2819	281	10	peae	peae	ADJ
fnp-2819	281	11	and	and	CCONJ
fnp-2819	281	12	epigenetic	epigenetic	ADJ
fnp-2819	281	13	regulation	regulation	NOUN
fnp-2819	281	14	of	of	ADP
fnp-2819	281	15	gene	gene	NOUN
fnp-2819	281	16	expression	expression	NOUN
fnp-2819	281	17	is	be	AUX
fnp-2819	281	18	unrelated	unrelated	ADJ
fnp-2819	281	19	to	to	ADP
fnp-2819	281	20	the	the	DET
fnp-2819	281	21	age	age	NOUN
fnp-2819	281	22	or	or	CCONJ
fnp-2819	281	23	the	the	DET
fnp-2819	281	24	glycemic	glycemic	ADJ
fnp-2819	281	25	status	status	NOUN
fnp-2819	281	26	of	of	ADP
fnp-2819	281	27	mice	mouse	NOUN
fnp-2819	281	28	.	.	PUNCT
fnp-2819	282	1	conclusions	conclusion	NOUN
fnp-2819	282	2	the	the	DET
fnp-2819	282	3	analysis	analysis	NOUN
fnp-2819	282	4	of	of	ADP
fnp-2819	282	5	the	the	DET
fnp-2819	282	6	41	41	NUM
fnp-2819	282	7	genes	gene	NOUN
fnp-2819	282	8	using	use	VERB
fnp-2819	282	9	qrt	qrt	ADJ
fnp-2819	282	10	-	-	PUNCT
fnp-2819	282	11	pcr	pcr	ADJ
fnp-2819	282	12	unraveled	unravel	VERB
fnp-2819	282	13	differential	differential	ADJ
fnp-2819	282	14	regulation	regulation	NOUN
fnp-2819	282	15	of	of	ADP
fnp-2819	282	16	gene	gene	NOUN
fnp-2819	282	17	expression	expression	NOUN
fnp-2819	282	18	in	in	ADP
fnp-2819	282	19	the	the	DET
fnp-2819	282	20	cns	cns	NOUN
fnp-2819	282	21	and	and	CCONJ
fnp-2819	282	22	slo	slo	PROPN
fnp-2819	282	23	by	by	ADP
fnp-2819	282	24	an	an	DET
fnp-2819	282	25	epigenetic	epigenetic	ADJ
fnp-2819	282	26	drug	drug	NOUN
fnp-2819	282	27	.	.	PUNCT
fnp-2819	283	1	this	this	DET
fnp-2819	283	2	study	study	NOUN
fnp-2819	283	3	has	have	AUX
fnp-2819	283	4	highlighted	highlight	VERB
fnp-2819	283	5	the	the	DET
fnp-2819	283	6	roles	role	NOUN
fnp-2819	283	7	of	of	ADP
fnp-2819	283	8	il4	il4	ADJ
fnp-2819	283	9	,	,	PUNCT
fnp-2819	283	10	hdac11	hdac11	NOUN
fnp-2819	283	11	,	,	PUNCT
fnp-2819	283	12	cd274	cd274	PROPN
fnp-2819	283	13	,	,	PUNCT
fnp-2819	283	14	and	and	CCONJ
fnp-2819	283	15	cd39	cd39	PROPN
fnp-2819	283	16	in	in	ADP
fnp-2819	283	17	the	the	DET
fnp-2819	283	18	cns	cns	NOUN
fnp-2819	283	19	in	in	ADP
fnp-2819	283	20	addition	addition	NOUN
fnp-2819	283	21	to	to	ADP
fnp-2819	283	22	validating	validate	VERB
fnp-2819	283	23	previously	previously	ADV
fnp-2819	283	24	implicated	implicate	VERB
fnp-2819	283	25	genes	gene	NOUN
fnp-2819	283	26	,	,	PUNCT
fnp-2819	283	27	il17a	il17a	PROPN
fnp-2819	283	28	,	,	PUNCT
fnp-2819	283	29	il22	il22	PROPN
fnp-2819	283	30	,	,	PUNCT
fnp-2819	283	31	inos	ino	NOUN
fnp-2819	283	32	,	,	PUNCT
fnp-2819	283	33	ahr	ahr	PROPN
fnp-2819	283	34	,	,	PUNCT
fnp-2819	283	35	and	and	CCONJ
fnp-2819	283	36	mif	mif	VERB
fnp-2819	283	37	in	in	ADP
fnp-2819	283	38	neuroinflammation	neuroinflammation	NOUN
fnp-2819	283	39	.	.	PUNCT
fnp-2819	284	1	on	on	ADP
fnp-2819	284	2	the	the	DET
fnp-2819	284	3	other	other	ADJ
fnp-2819	284	4	hand	hand	NOUN
fnp-2819	284	5	,	,	PUNCT
fnp-2819	284	6	in	in	ADP
fnp-2819	284	7	the	the	DET
fnp-2819	284	8	slo	slo	PROPN
fnp-2819	284	9	,	,	PUNCT
fnp-2819	284	10	the	the	DET
fnp-2819	284	11	roles	role	NOUN
fnp-2819	284	12	of	of	ADP
fnp-2819	284	13	il22	il22	PROPN
fnp-2819	284	14	,	,	PUNCT
fnp-2819	284	15	il27	il27	PROPN
fnp-2819	284	16	,	,	PUNCT
fnp-2819	284	17	nos2	nos2	NOUN
fnp-2819	284	18	,	,	PUNCT
fnp-2819	284	19	and	and	CCONJ
fnp-2819	284	20	mif	mif	PROPN
fnp-2819	284	21	were	be	AUX
fnp-2819	284	22	confirmed	confirm	VERB
fnp-2819	284	23	while	while	SCONJ
fnp-2819	284	24	indicating	indicate	VERB
fnp-2819	284	25	the	the	DET
fnp-2819	284	26	participation	participation	NOUN
fnp-2819	284	27	of	of	ADP
fnp-2819	284	28	cd274	cd274	PROPN
fnp-2819	284	29	and	and	CCONJ
fnp-2819	284	30	cd39	cd39	PROPN
fnp-2819	284	31	in	in	ADP
fnp-2819	284	32	peae	peae	PROPN
fnp-2819	284	33	.	.	PUNCT
fnp-2819	285	1	some	some	PRON
fnp-2819	285	2	of	of	ADP
fnp-2819	285	3	these	these	DET
fnp-2819	285	4	genes	gene	NOUN
fnp-2819	285	5	are	be	AUX
fnp-2819	285	6	induced	induce	VERB
fnp-2819	285	7	by	by	ADP
fnp-2819	285	8	immunization	immunization	NOUN
fnp-2819	285	9	,	,	PUNCT
fnp-2819	285	10	while	while	SCONJ
fnp-2819	285	11	others	other	NOUN
fnp-2819	285	12	are	be	AUX
fnp-2819	285	13	constitutively	constitutively	ADV
fnp-2819	285	14	expressed	express	VERB
fnp-2819	285	15	.	.	PUNCT
fnp-2819	286	1	surprisingly	surprisingly	ADV
fnp-2819	286	2	,	,	PUNCT
fnp-2819	286	3	many	many	ADJ
fnp-2819	286	4	other	other	ADJ
fnp-2819	286	5	genes	gene	NOUN
fnp-2819	286	6	previously	previously	ADV
fnp-2819	286	7	implicated	implicate	VERB
fnp-2819	286	8	in	in	ADP
fnp-2819	286	9	eae	eae	PROPN
fnp-2819	286	10	were	be	AUX
fnp-2819	286	11	refractory	refractory	NOUN
fnp-2819	286	12	to	to	ADP
fnp-2819	286	13	histone	histone	NOUN
fnp-2819	286	14	hyperacetylation	hyperacetylation	NOUN
fnp-2819	286	15	mediated	mediate	VERB
fnp-2819	286	16	transcriptional	transcriptional	ADJ
fnp-2819	286	17	regulation	regulation	NOUN
fnp-2819	286	18	.	.	PUNCT
fnp-2819	287	1	hence	hence	ADV
fnp-2819	287	2	,	,	PUNCT
fnp-2819	287	3	it	it	PRON
fnp-2819	287	4	will	will	AUX
fnp-2819	287	5	be	be	AUX
fnp-2819	287	6	difficult	difficult	ADJ
fnp-2819	287	7	to	to	PART
fnp-2819	287	8	conclude	conclude	VERB
fnp-2819	287	9	whether	whether	SCONJ
fnp-2819	287	10	these	these	DET
fnp-2819	287	11	genes	gene	NOUN
fnp-2819	287	12	do	do	AUX
fnp-2819	287	13	not	not	PART
fnp-2819	287	14	contribute	contribute	VERB
fnp-2819	287	15	to	to	ADP
fnp-2819	287	16	neuroinflammation	neuroinflammation	NOUN
fnp-2819	287	17	.	.	PUNCT
fnp-2819	288	1	nevertheless	nevertheless	ADV
fnp-2819	288	2	,	,	PUNCT
fnp-2819	288	3	our	our	PRON
fnp-2819	288	4	data	datum	NOUN
fnp-2819	288	5	suggest	suggest	VERB
fnp-2819	288	6	that	that	SCONJ
fnp-2819	288	7	the	the	DET
fnp-2819	288	8	drug	drug	NOUN
fnp-2819	288	9	-	-	PUNCT
fnp-2819	288	10	induced	induce	VERB
fnp-2819	288	11	histone	histone	NOUN
fnp-2819	288	12	hyperacetylation	hyperacetylation	NOUN
fnp-2819	288	13	is	be	AUX
fnp-2819	288	14	a	a	DET
fnp-2819	288	15	promising	promising	ADJ
fnp-2819	288	16	strategy	strategy	NOUN
fnp-2819	288	17	to	to	PART
fnp-2819	288	18	treat	treat	VERB
fnp-2819	288	19	demyelination	demyelination	NOUN
fnp-2819	288	20	and	and	CCONJ
fnp-2819	288	21	axonal	axonal	ADJ
fnp-2819	288	22	damage	damage	NOUN
fnp-2819	288	23	by	by	ADP
fnp-2819	288	24	modifying	modify	VERB
fnp-2819	288	25	the	the	DET
fnp-2819	288	26	expression	expression	NOUN
fnp-2819	288	27	of	of	ADP
fnp-2819	288	28	selected	select	VERB
fnp-2819	288	29	genes	gene	NOUN
fnp-2819	288	30	.	.	PUNCT
fnp-2819	289	1	although	although	SCONJ
fnp-2819	289	2	the	the	DET
fnp-2819	289	3	therapeutic	therapeutic	ADJ
fnp-2819	289	4	potential	potential	NOUN
fnp-2819	289	5	of	of	ADP
fnp-2819	289	6	hdac	hdac	NOUN
fnp-2819	289	7	inhibitors	inhibitor	NOUN
fnp-2819	289	8	for	for	ADP
fnp-2819	289	9	the	the	DET
fnp-2819	289	10	treatment	treatment	NOUN
fnp-2819	289	11	of	of	ADP
fnp-2819	289	12	multiple	multiple	ADJ
fnp-2819	289	13	sclerosis	sclerosis	NOUN
fnp-2819	289	14	has	have	AUX
fnp-2819	289	15	been	be	AUX
fnp-2819	289	16	entertained	entertain	VERB
fnp-2819	289	17	(	(	PUNCT
fnp-2819	289	18	faraco	faraco	PROPN
fnp-2819	289	19	et	et	PROPN
fnp-2819	289	20	al	al	PROPN
fnp-2819	289	21	.	.	PROPN
fnp-2819	289	22	,	,	PUNCT
fnp-2819	289	23	2011	2011	NUM
fnp-2819	289	24	)	)	PUNCT
fnp-2819	289	25	,	,	PUNCT
fnp-2819	289	26	direct	direct	ADJ
fnp-2819	289	27	evidence	evidence	NOUN
fnp-2819	289	28	is	be	AUX
fnp-2819	289	29	lacking	lack	VERB
fnp-2819	289	30	(	(	PUNCT
fnp-2819	289	31	göbel	göbel	NOUN
fnp-2819	289	32	et	et	PROPN
fnp-2819	289	33	al	al	PROPN
fnp-2819	289	34	.	.	PROPN
fnp-2819	289	35	,	,	PUNCT
fnp-2819	289	36	2018	2018	NUM
fnp-2819	289	37	)	)	PUNCT
fnp-2819	289	38	.	.	PUNCT
fnp-2819	290	1	the	the	DET
fnp-2819	290	2	data	datum	NOUN
fnp-2819	290	3	generated	generate	VERB
fnp-2819	290	4	in	in	ADP
fnp-2819	290	5	the	the	DET
fnp-2819	290	6	nod	nod	PROPN
fnp-2819	290	7	mouse	mouse	NOUN
fnp-2819	290	8	model	model	NOUN
fnp-2819	290	9	provide	provide	VERB
fnp-2819	290	10	a	a	DET
fnp-2819	290	11	framework	framework	NOUN
fnp-2819	290	12	for	for	ADP
fnp-2819	290	13	a	a	DET
fnp-2819	290	14	similar	similar	ADJ
fnp-2819	290	15	pharmacological	pharmacological	ADJ
fnp-2819	290	16	approach	approach	NOUN
fnp-2819	290	17	to	to	PART
fnp-2819	290	18	treat	treat	VERB
fnp-2819	290	19	ms	ms	ADJ
fnp-2819	290	20	patients	patient	NOUN
fnp-2819	290	21	.	.	PUNCT
fnp-2819	291	1	author	author	NOUN
fnp-2819	291	2	contributions	contribution	NOUN
fnp-2819	291	3	aj	aj	PROPN
fnp-2819	291	4	conducted	conduct	VERB
fnp-2819	291	5	experiments	experiment	NOUN
fnp-2819	291	6	,	,	PUNCT
fnp-2819	291	7	collected	collect	VERB
fnp-2819	291	8	data	datum	NOUN
fnp-2819	291	9	,	,	PUNCT
fnp-2819	291	10	edited	edit	VERB
fnp-2819	291	11	the	the	DET
fnp-2819	291	12	graphic	graphic	NOUN
fnp-2819	291	13	and	and	CCONJ
fnp-2819	291	14	the	the	DET
fnp-2819	291	15	manuscript	manuscript	NOUN
fnp-2819	291	16	.	.	PUNCT
fnp-2819	292	1	ka	ka	PROPN
fnp-2819	292	2	,	,	PUNCT
fnp-2819	292	3	rk	rk	INTJ
fnp-2819	292	4	,	,	PUNCT
fnp-2819	292	5	as	as	ADP
fnp-2819	292	6	,	,	PUNCT
fnp-2819	292	7	ak	ak	PROPN
fnp-2819	292	8	,	,	PUNCT
fnp-2819	292	9	and	and	CCONJ
fnp-2819	292	10	mk	mk	NOUN
fnp-2819	292	11	performed	perform	VERB
fnp-2819	292	12	experiments	experiment	NOUN
fnp-2819	292	13	,	,	PUNCT
fnp-2819	292	14	collected	collect	VERB
fnp-2819	292	15	data	datum	NOUN
fnp-2819	292	16	,	,	PUNCT
fnp-2819	292	17	and	and	CCONJ
fnp-2819	292	18	approved	approve	VERB
fnp-2819	292	19	the	the	DET
fnp-2819	292	20	manuscript	manuscript	NOUN
fnp-2819	292	21	.	.	PUNCT
fnp-2819	293	1	sj	sj	PROPN
fnp-2819	293	2	conceived	conceive	VERB
fnp-2819	293	3	the	the	DET
fnp-2819	293	4	project	project	NOUN
fnp-2819	293	5	,	,	PUNCT
fnp-2819	293	6	designed	design	VERB
fnp-2819	293	7	and	and	CCONJ
fnp-2819	293	8	implemented	implement	VERB
fnp-2819	293	9	experiments	experiment	NOUN
fnp-2819	293	10	,	,	PUNCT
fnp-2819	293	11	analyzed	analyze	VERB
fnp-2819	293	12	the	the	DET
fnp-2819	293	13	data	datum	NOUN
fnp-2819	293	14	,	,	PUNCT
fnp-2819	293	15	and	and	CCONJ
fnp-2819	293	16	wrote	write	VERB
fnp-2819	293	17	the	the	DET
fnp-2819	293	18	paper	paper	NOUN
fnp-2819	293	19	.	.	PUNCT
fnp-2819	294	1	funding	fund	VERB
fnp-2819	294	2	this	this	DET
fnp-2819	294	3	research	research	NOUN
fnp-2819	294	4	did	do	AUX
fnp-2819	294	5	not	not	PART
fnp-2819	294	6	receive	receive	VERB
fnp-2819	294	7	any	any	DET
fnp-2819	294	8	specific	specific	ADJ
fnp-2819	294	9	grant	grant	NOUN
fnp-2819	294	10	from	from	ADP
fnp-2819	294	11	funding	fund	VERB
fnp-2819	294	12	agencies	agency	NOUN
fnp-2819	294	13	in	in	ADP
fnp-2819	294	14	the	the	DET
fnp-2819	294	15	public	public	ADJ
fnp-2819	294	16	,	,	PUNCT
fnp-2819	294	17	commercial	commercial	ADJ
fnp-2819	294	18	,	,	PUNCT
fnp-2819	294	19	or	or	CCONJ
fnp-2819	294	20	not	not	PART
fnp-2819	294	21	-	-	PUNCT
fnp-2819	294	22	for	for	ADP
fnp-2819	294	23	-	-	PUNCT
fnp-2819	294	24	profit	profit	NOUN
fnp-2819	294	25	sectors	sector	NOUN
fnp-2819	294	26	.	.	PUNCT
fnp-2819	295	1	acknowledgments	acknowledgment	NOUN
fnp-2819	295	2	mark	mark	PROPN
fnp-2819	295	3	holterman	holterman	PROPN
fnp-2819	295	4	and	and	CCONJ
fnp-2819	295	5	bellur	bellur	PROPN
fnp-2819	295	6	prabhakar	prabhakar	PROPN
fnp-2819	295	7	are	be	AUX
fnp-2819	295	8	acknowledged	acknowledge	VERB
fnp-2819	295	9	for	for	ADP
fnp-2819	295	10	the	the	DET
fnp-2819	295	11	support	support	NOUN
fnp-2819	295	12	of	of	ADP
fnp-2819	295	13	this	this	DET
fnp-2819	295	14	work	work	NOUN
fnp-2819	295	15	.	.	PUNCT
fnp-2819	296	1	references	reference	NOUN
fnp-2819	296	2	basso	basso	NOUN
fnp-2819	296	3	,	,	PUNCT
fnp-2819	296	4	a.s	a.s	PROPN
fnp-2819	296	5	.	.	PROPN
fnp-2819	296	6	,	,	PUNCT
fnp-2819	296	7	frenkel	frenkel	PROPN
fnp-2819	296	8	,	,	PUNCT
fnp-2819	296	9	d.	d.	PROPN
fnp-2819	296	10	,	,	PUNCT
fnp-2819	296	11	quintana	quintana	PROPN
fnp-2819	296	12	,	,	PUNCT
fnp-2819	296	13	f.j	f.j	PROPN
fnp-2819	296	14	.	.	PROPN
fnp-2819	296	15	,	,	PUNCT
fnp-2819	296	16	costa	costa	NOUN
fnp-2819	296	17	-	-	PUNCT
fnp-2819	296	18	pinto	pinto	NOUN
fnp-2819	296	19	,	,	PUNCT
fnp-2819	296	20	f.a	f.a	PROPN
fnp-2819	296	21	.	.	PROPN
fnp-2819	296	22	,	,	PUNCT
fnp-2819	296	23	petrovic	petrovic	PROPN
fnp-2819	296	24	-	-	PUNCT
fnp-2819	296	25	stojkovic	stojkovic	PROPN
fnp-2819	296	26	,	,	PUNCT
fnp-2819	296	27	s.	s.	PROPN
fnp-2819	296	28	,	,	PUNCT
fnp-2819	296	29	puckett	puckett	PROPN
fnp-2819	296	30	,	,	PUNCT
fnp-2819	296	31	l.	l.	PROPN
fnp-2819	296	32	,	,	PUNCT
fnp-2819	296	33	monsonego	monsonego	PROPN
fnp-2819	296	34	,	,	PUNCT
fnp-2819	296	35	a.	a.	NOUN
fnp-2819	296	36	,	,	PUNCT
fnp-2819	296	37	bar	bar	NOUN
fnp-2819	296	38	-	-	PUNCT
fnp-2819	296	39	shir	shir	NOUN
fnp-2819	296	40	a.	a.	NOUN
fnp-2819	296	41	,	,	PUNCT
fnp-2819	296	42	engel	engel	PROPN
fnp-2819	296	43	y.	y.	PROPN
fnp-2819	296	44	,	,	PUNCT
fnp-2819	296	45	gozin	gozin	NOUN
fnp-2819	296	46	m.	m.	NOUN
fnp-2819	296	47	,	,	PUNCT
fnp-2819	296	48	weiner	weiner	NOUN
fnp-2819	296	49	h.l	h.l	PROPN
fnp-2819	296	50	.	.	PROPN
fnp-2819	296	51	,	,	PUNCT
fnp-2819	296	52	2008	2008	NUM
fnp-2819	296	53	.	.	PUNCT
fnp-2819	297	1	reversal	reversal	NOUN
fnp-2819	297	2	of	of	ADP
fnp-2819	297	3	axonal	axonal	ADJ
fnp-2819	297	4	loss	loss	NOUN
fnp-2819	297	5	and	and	CCONJ
fnp-2819	297	6	disability	disability	NOUN
fnp-2819	297	7	in	in	ADP
fnp-2819	297	8	a	a	DET
fnp-2819	297	9	mouse	mouse	NOUN
fnp-2819	297	10	model	model	NOUN
fnp-2819	297	11	of	of	ADP
fnp-2819	297	12	progressive	progressive	ADJ
fnp-2819	297	13	multiple	multiple	ADJ
fnp-2819	297	14	sclerosis	sclerosis	NOUN
fnp-2819	297	15	.	.	PUNCT
fnp-2819	298	1	j.	j.	PROPN
fnp-2819	298	2	clin	clin	PROPN
fnp-2819	298	3	.	.	PUNCT
fnp-2819	299	1	invest	invest	VERB
fnp-2819	299	2	.	.	PUNCT
fnp-2819	300	1	118	118	NUM
fnp-2819	300	2	,	,	PUNCT
fnp-2819	300	3	1532	1532	NUM
fnp-2819	300	4	-	-	SYM
fnp-2819	300	5	1543	1543	NUM
fnp-2819	300	6	.	.	PUNCT
fnp-2819	301	1	https://doi.org/10.1172/jci33464	https://doi.org/10.1172/jci33464	ADV
fnp-2819	301	2	.	.	PUNCT
fnp-2819	302	1	borjini	borjini	PROPN
fnp-2819	302	2	,	,	PUNCT
fnp-2819	302	3	n.	n.	NOUN
fnp-2819	302	4	,	,	PUNCT
fnp-2819	302	5	fernández	fernández	PROPN
fnp-2819	302	6	,	,	PUNCT
fnp-2819	302	7	m.	m.	NOUN
fnp-2819	302	8	,	,	PUNCT
fnp-2819	302	9	giardino	giardino	PROPN
fnp-2819	302	10	l.	l.	PROPN
fnp-2819	302	11	,	,	PUNCT
fnp-2819	302	12	calzà	calzà	NOUN
fnp-2819	302	13	,	,	PUNCT
fnp-2819	302	14	l.	l.	PROPN
fnp-2819	302	15	,	,	PUNCT
fnp-2819	302	16	2016	2016	NUM
fnp-2819	302	17	.	.	PUNCT
fnp-2819	303	1	cytokine	cytokine	VERB
fnp-2819	303	2	and	and	CCONJ
fnp-2819	303	3	chemokine	chemokine	ADJ
fnp-2819	303	4	alterations	alteration	NOUN
fnp-2819	303	5	in	in	ADP
fnp-2819	303	6	tissue	tissue	NOUN
fnp-2819	303	7	,	,	PUNCT
fnp-2819	303	8	csf	csf	NOUN
fnp-2819	303	9	,	,	PUNCT
fnp-2819	303	10	and	and	CCONJ
fnp-2819	303	11	plasma	plasma	NOUN
fnp-2819	303	12	in	in	ADP
fnp-2819	303	13	early	early	ADJ
fnp-2819	303	14	presymptomatic	presymptomatic	ADJ
fnp-2819	303	15	phase	phase	NOUN
fnp-2819	303	16	of	of	ADP
fnp-2819	303	17	experimental	experimental	ADJ
fnp-2819	303	18	allergic	allergic	ADJ
fnp-2819	303	19	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	303	20	(	(	PUNCT
fnp-2819	303	21	eae	eae	PROPN
fnp-2819	303	22	)	)	PUNCT
fnp-2819	303	23	,	,	PUNCT
fnp-2819	303	24	in	in	ADP
fnp-2819	303	25	a	a	DET
fnp-2819	303	26	rat	rat	NOUN
fnp-2819	303	27	model	model	NOUN
fnp-2819	303	28	of	of	ADP
fnp-2819	303	29	multiple	multiple	ADJ
fnp-2819	303	30	sclerosis	sclerosis	NOUN
fnp-2819	303	31	.	.	PUNCT
fnp-2819	304	1	j.	j.	PROPN
fnp-2819	304	2	neuroinflammation	neuroinflammation	PROPN
fnp-2819	304	3	13	13	NUM
fnp-2819	304	4	,	,	PUNCT
fnp-2819	304	5	291	291	NUM
fnp-2819	304	6	.	.	PUNCT
fnp-2819	305	1	https://doi.org.10.1186	https://doi.org.10.1186	PROPN
fnp-2819	305	2	/	/	SYM
fnp-2819	305	3	s12974	s12974	NOUN
fnp-2819	305	4	-	-	PUNCT
fnp-2819	305	5	016	016	NUM
fnp-2819	305	6	-	-	PUNCT
fnp-2819	305	7	0757	0757	NUM
fnp-2819	305	8	-	-	PUNCT
fnp-2819	305	9	6	6	NUM
fnp-2819	305	10	.	.	PUNCT
fnp-2819	306	1	bradner	bradner	NOUN
fnp-2819	306	2	,	,	PUNCT
fnp-2819	306	3	j.e	j.e	PROPN
fnp-2819	306	4	.	.	PROPN
fnp-2819	306	5	,	,	PUNCT
fnp-2819	306	6	west	west	PROPN
fnp-2819	306	7	,	,	PUNCT
fnp-2819	306	8	n.	n.	NOUN
fnp-2819	306	9	,	,	PUNCT
fnp-2819	306	10	grachan	grachan	PROPN
fnp-2819	306	11	,	,	PUNCT
fnp-2819	306	12	m.l	m.l	PROPN
fnp-2819	306	13	.	.	PROPN
fnp-2819	306	14	,	,	PUNCT
fnp-2819	306	15	greenberg	greenberg	PROPN
fnp-2819	306	16	,	,	PUNCT
fnp-2819	306	17	e.f	e.f	PROPN
fnp-2819	306	18	.	.	PROPN
fnp-2819	306	19	,	,	PUNCT
fnp-2819	306	20	haggarty	haggarty	PROPN
fnp-2819	306	21	,	,	PUNCT
fnp-2819	306	22	s.j	s.j	PROPN
fnp-2819	306	23	.	.	PROPN
fnp-2819	306	24	,	,	PUNCT
fnp-2819	306	25	warnow	warnow	PROPN
fnp-2819	306	26	,	,	PUNCT
fnp-2819	306	27	t.	t.	PROPN
fnp-2819	306	28	,	,	PUNCT
fnp-2819	306	29	mazitschek	mazitschek	PROPN
fnp-2819	306	30	,	,	PUNCT
fnp-2819	306	31	r.	r.	PROPN
fnp-2819	306	32	,	,	PUNCT
fnp-2819	306	33	2010	2010	NUM
fnp-2819	306	34	.	.	PUNCT
fnp-2819	307	1	chemical	chemical	ADJ
fnp-2819	307	2	phylogenetics	phylogenetic	NOUN
fnp-2819	307	3	of	of	ADP
fnp-2819	307	4	histone	histone	NOUN
fnp-2819	307	5	deacetylases	deacetylase	NOUN
fnp-2819	307	6	.	.	PUNCT
fnp-2819	308	1	nat	nat	PROPN
fnp-2819	308	2	.	.	PUNCT
fnp-2819	309	1	chem	chem	PROPN
fnp-2819	309	2	.	.	PUNCT
fnp-2819	310	1	biol	biol	PROPN
fnp-2819	310	2	.	.	PUNCT
fnp-2819	311	1	6	6	NUM
fnp-2819	311	2	,	,	PUNCT
fnp-2819	311	3	238	238	NUM
fnp-2819	311	4	-	-	SYM
fnp-2819	311	5	243	243	NUM
fnp-2819	311	6	.	.	PUNCT
fnp-2819	311	7	https://doi.org.10.1038	https://doi.org.10.1038	PROPN
fnp-2819	311	8	/	/	SYM
fnp-2819	311	9	nchembio.313	nchembio.313	PROPN
fnp-2819	311	10	.	.	PUNCT
fnp-2819	312	1	dang	dang	PROPN
fnp-2819	312	2	,	,	PUNCT
fnp-2819	312	3	p.t	p.t	PROPN
fnp-2819	312	4	.	.	PROPN
fnp-2819	312	5	,	,	PUNCT
fnp-2819	312	6	bui	bui	PROPN
fnp-2819	312	7	,	,	PUNCT
fnp-2819	312	8	q.	q.	PROPN
fnp-2819	312	9	,	,	PUNCT
fnp-2819	312	10	d'souza	d'souza	PROPN
fnp-2819	312	11	,	,	PUNCT
fnp-2819	312	12	c.s	c.s	PROPN
fnp-2819	312	13	.	.	PROPN
fnp-2819	312	14	,	,	PUNCT
fnp-2819	312	15	orian	orian	PROPN
fnp-2819	312	16	,	,	PUNCT
fnp-2819	312	17	j.m	j.m	PROPN
fnp-2819	312	18	.	.	PROPN
fnp-2819	312	19	,	,	PUNCT
fnp-2819	312	20	2015	2015	NUM
fnp-2819	312	21	.	.	PUNCT
fnp-2819	313	1	modelling	model	VERB
fnp-2819	313	2	ms	ms	NOUN
fnp-2819	313	3	:	:	PUNCT
fnp-2819	313	4	chronic	chronic	NOUN
fnp-2819	313	5	-	-	PUNCT
fnp-2819	313	6	relapsing	relapse	VERB
fnp-2819	313	7	eae	eae	NOUN
fnp-2819	313	8	in	in	ADP
fnp-2819	313	9	the	the	DET
fnp-2819	313	10	nod	nod	PROPN
fnp-2819	313	11	/	/	SYM
fnp-2819	313	12	lt	lt	PROPN
fnp-2819	313	13	mouse	mouse	NOUN
fnp-2819	313	14	strain	strain	NOUN
fnp-2819	313	15	.	.	PUNCT
fnp-2819	314	1	curr	curr	PROPN
fnp-2819	314	2	.	.	PUNCT
fnp-2819	314	3	top	top	PROPN
fnp-2819	314	4	.	.	PUNCT
fnp-2819	314	5	behav	behav	PROPN
fnp-2819	314	6	.	.	PUNCT
fnp-2819	315	1	neurosci	neurosci	PROPN
fnp-2819	315	2	.	.	PUNCT
fnp-2819	316	1	26	26	NUM
fnp-2819	316	2	,	,	PUNCT
fnp-2819	316	3	143	143	NUM
fnp-2819	316	4	-	-	SYM
fnp-2819	316	5	177	177	NUM
fnp-2819	316	6	.	.	PUNCT
fnp-2819	317	1	https://doi.org.10.1007/7854_2015_378	https://doi.org.10.1007/7854_2015_378	PROPN
fnp-2819	317	2	.	.	PUNCT
fnp-2819	318	1	danikowski	danikowski	PROPN
fnp-2819	318	2	,	,	PUNCT
fnp-2819	318	3	k.m	k.m	PROPN
fnp-2819	318	4	.	.	PROPN
fnp-2819	318	5	,	,	PUNCT
fnp-2819	318	6	jayaraman	jayaraman	NOUN
fnp-2819	318	7	,	,	PUNCT
fnp-2819	318	8	s.	s.	PROPN
fnp-2819	318	9	,	,	PUNCT
fnp-2819	318	10	prabhakar	prabhakar	PROPN
fnp-2819	318	11	,	,	PUNCT
fnp-2819	318	12	b.s	b.s	PROPN
fnp-2819	318	13	.	.	PROPN
fnp-2819	318	14	,	,	PUNCT
fnp-2819	318	15	2017	2017	NUM
fnp-2819	318	16	.	.	PUNCT
fnp-2819	319	1	regulatory	regulatory	ADJ
fnp-2819	319	2	t	t	PROPN
fnp-2819	319	3	cells	cell	NOUN
fnp-2819	319	4	in	in	ADP
fnp-2819	319	5	multiple	multiple	ADJ
fnp-2819	319	6	sclerosis	sclerosis	NOUN
fnp-2819	319	7	and	and	CCONJ
fnp-2819	319	8	myasthenia	myasthenia	NOUN
fnp-2819	319	9	gravis	gravis	PROPN
fnp-2819	319	10	.	.	PUNCT
fnp-2819	320	1	j.	j.	PROPN
fnp-2819	320	2	neuroinflammation	neuroinflammation	PROPN
fnp-2819	320	3	14	14	NUM
fnp-2819	320	4	,	,	PUNCT
fnp-2819	320	5	117	117	NUM
fnp-2819	320	6	.	.	PUNCT
fnp-2819	321	1	https://doi.org.10.1186	https://doi.org.10.1186	PROPN
fnp-2819	321	2	/	/	SYM
fnp-2819	321	3	s12974	s12974	PROPN
fnp-2819	321	4	-	-	PUNCT
fnp-2819	321	5	017	017	NUM
fnp-2819	321	6	-	-	PUNCT
fnp-2819	321	7	0892	0892	NUM
fnp-2819	321	8	-	-	PUNCT
fnp-2819	321	9	8	8	NUM
fnp-2819	321	10	.	.	PUNCT
fnp-2819	322	1	dendrou	dendrou	PROPN
fnp-2819	322	2	,	,	PUNCT
fnp-2819	322	3	c.a	c.a	PROPN
fnp-2819	322	4	.	.	PROPN
fnp-2819	322	5	,	,	PUNCT
fnp-2819	322	6	fugger	fugger	NOUN
fnp-2819	322	7	,	,	PUNCT
fnp-2819	322	8	l.	l.	PROPN
fnp-2819	322	9	,	,	PUNCT
fnp-2819	322	10	friese	friese	PROPN
fnp-2819	322	11	,	,	PUNCT
fnp-2819	322	12	m.a	m.a	PROPN
fnp-2819	322	13	.	.	PROPN
fnp-2819	322	14	,	,	PUNCT
fnp-2819	322	15	2015	2015	NUM
fnp-2819	322	16	.	.	PUNCT
fnp-2819	323	1	immunopathology	immunopathology	NOUN
fnp-2819	323	2	of	of	ADP
fnp-2819	323	3	multiple	multiple	ADJ
fnp-2819	323	4	sclerosis	sclerosis	NOUN
fnp-2819	323	5	.	.	PUNCT
fnp-2819	324	1	nat	nat	PROPN
fnp-2819	324	2	.	.	PUNCT
fnp-2819	325	1	rev	rev	PROPN
fnp-2819	325	2	.	.	PROPN
fnp-2819	325	3	immunol	immunol	NOUN
fnp-2819	325	4	.	.	PUNCT
fnp-2819	326	1	15	15	NUM
fnp-2819	326	2	,	,	PUNCT
fnp-2819	326	3	545	545	NUM
fnp-2819	326	4	-	-	SYM
fnp-2819	326	5	558	558	NUM
fnp-2819	326	6	.	.	PUNCT
fnp-2819	327	1	https://doi.org.10.1038	https://doi.org.10.1038	PROPN
fnp-2819	327	2	/	/	SYM
fnp-2819	327	3	nri3871	nri3871	PROPN
fnp-2819	327	4	.	.	PUNCT
fnp-2819	328	1	de	de	X
fnp-2819	328	2	ruijter	ruijter	PROPN
fnp-2819	328	3	,	,	PUNCT
fnp-2819	328	4	a.j	a.j	PROPN
fnp-2819	328	5	.	.	PROPN
fnp-2819	328	6	,	,	PUNCT
fnp-2819	328	7	van	van	PROPN
fnp-2819	328	8	gennip	gennip	PROPN
fnp-2819	328	9	,	,	PUNCT
fnp-2819	328	10	a.h	a.h	PROPN
fnp-2819	328	11	.	.	PROPN
fnp-2819	328	12	,	,	PUNCT
fnp-2819	328	13	caron	caron	PROPN
fnp-2819	328	14	,	,	PUNCT
fnp-2819	328	15	h.n	h.n	PROPN
fnp-2819	328	16	.	.	PROPN
fnp-2819	328	17	,	,	PUNCT
fnp-2819	328	18	kemp	kemp	PROPN
fnp-2819	328	19	,	,	PUNCT
fnp-2819	328	20	s.	s.	PROPN
fnp-2819	328	21	,	,	PUNCT
fnp-2819	328	22	van	van	PROPN
fnp-2819	328	23	kuilenburg	kuilenburg	PROPN
fnp-2819	328	24	,	,	PUNCT
fnp-2819	328	25	a.b	a.b	PROPN
fnp-2819	328	26	.	.	PROPN
fnp-2819	328	27	,	,	PUNCT
fnp-2819	328	28	2003	2003	NUM
fnp-2819	328	29	.	.	PUNCT
fnp-2819	329	1	histone	histone	NOUN
fnp-2819	329	2	deacetylases	deacetylase	NOUN
fnp-2819	329	3	(	(	PUNCT
fnp-2819	329	4	hdacs	hdac	NOUN
fnp-2819	329	5	):	):	PUNCT
fnp-2819	329	6	characterization	characterization	NOUN
fnp-2819	329	7	of	of	ADP
fnp-2819	329	8	the	the	DET
fnp-2819	329	9	classical	classical	ADJ
fnp-2819	329	10	hdac	hdac	NOUN
fnp-2819	329	11	family	family	NOUN
fnp-2819	329	12	.	.	PUNCT
fnp-2819	330	1	biochem	biochem	PROPN
fnp-2819	330	2	.	.	PUNCT
fnp-2819	331	1	j.	j.	PROPN
fnp-2819	331	2	370	370	NUM
fnp-2819	331	3	,	,	PUNCT
fnp-2819	331	4	737	737	NUM
fnp-2819	331	5	-	-	SYM
fnp-2819	331	6	749	749	NUM
fnp-2819	331	7	.	.	PUNCT
fnp-2819	332	1	pmid:12429021	pmid:12429021	NOUN
fnp-2819	332	2	.	.	PUNCT
fnp-2819	333	1	el	el	PROPN
fnp-2819	333	2	-	-	PUNCT
fnp-2819	333	3	behi	behi	PROPN
fnp-2819	333	4	,	,	PUNCT
fnp-2819	333	5	m.	m.	NOUN
fnp-2819	333	6	,	,	PUNCT
fnp-2819	333	7	ciric	ciric	ADJ
fnp-2819	333	8	,	,	PUNCT
fnp-2819	333	9	b.	b.	PROPN
fnp-2819	333	10	,	,	PUNCT
fnp-2819	333	11	dai	dai	PROPN
fnp-2819	333	12	,	,	PUNCT
fnp-2819	333	13	h.	h.	PROPN
fnp-2819	333	14	,	,	PUNCT
fnp-2819	333	15	yan	yan	PROPN
fnp-2819	333	16	,	,	PUNCT
fnp-2819	333	17	y.	y.	PROPN
fnp-2819	333	18	,	,	PUNCT
fnp-2819	333	19	cullimore	cullimore	PROPN
fnp-2819	333	20	,	,	PUNCT
fnp-2819	333	21	m.	m.	NOUN
fnp-2819	333	22	,	,	PUNCT
fnp-2819	333	23	safavi	safavi	PROPN
fnp-2819	333	24	,	,	PUNCT
fnp-2819	333	25	f.	f.	PROPN
fnp-2819	333	26	,	,	PUNCT
fnp-2819	333	27	zhang	zhang	PROPN
fnp-2819	333	28	,	,	PUNCT
fnp-2819	333	29	g.x	g.x	PROPN
fnp-2819	333	30	.	.	PROPN
fnp-2819	333	31	,	,	PUNCT
fnp-2819	333	32	dittel	dittel	NOUN
fnp-2819	333	33	,	,	PUNCT
fnp-2819	333	34	b.n	b.n	PROPN
fnp-2819	333	35	.	.	PROPN
fnp-2819	333	36	,	,	PUNCT
fnp-2819	333	37	rostami	rostami	PROPN
fnp-2819	333	38	,	,	PUNCT
fnp-2819	333	39	a.	a.	NOUN
fnp-2819	333	40	,	,	PUNCT
fnp-2819	333	41	2011	2011	NUM
fnp-2819	333	42	.	.	PUNCT
fnp-2819	334	1	the	the	DET
fnp-2819	334	2	encephalitogenicity	encephalitogenicity	NOUN
fnp-2819	334	3	of	of	ADP
fnp-2819	334	4	t(h)17	t(h)17	NOUN
fnp-2819	334	5	cells	cell	NOUN
fnp-2819	334	6	is	be	AUX
fnp-2819	334	7	dependent	dependent	ADJ
fnp-2819	334	8	on	on	ADP
fnp-2819	334	9	il-1and	il-1and	DET
fnp-2819	334	10	il-23	il-23	NOUN
fnp-2819	334	11	-	-	PUNCT
fnp-2819	334	12	induced	induce	VERB
fnp-2819	334	13	production	production	NOUN
fnp-2819	334	14	of	of	ADP
fnp-2819	334	15	the	the	DET
fnp-2819	334	16	cytokine	cytokine	NOUN
fnp-2819	334	17	gm	gm	PROPN
fnp-2819	334	18	-	-	PUNCT
fnp-2819	334	19	csf	csf	PROPN
fnp-2819	334	20	.	.	PUNCT
fnp-2819	335	1	nat	nat	PROPN
fnp-2819	335	2	.	.	PUNCT
fnp-2819	336	1	immunol	immunol	NOUN
fnp-2819	336	2	.	.	PUNCT
fnp-2819	337	1	12	12	NUM
fnp-2819	337	2	,	,	PUNCT
fnp-2819	337	3	568	568	NUM
fnp-2819	337	4	-	-	SYM
fnp-2819	337	5	575	575	NUM
fnp-2819	337	6	.	.	PUNCT
fnp-2819	338	1	https://doi.org.10.1038	https://doi.org.10.1038	PROPN
fnp-2819	338	2	/	/	SYM
fnp-2819	338	3	ni.2031	ni.2031	PROPN
fnp-2819	338	4	.	.	PUNCT
fnp-2819	338	5	evangelidou	evangelidou	NOUN
fnp-2819	338	6	,	,	PUNCT
fnp-2819	338	7	m.	m.	NOUN
fnp-2819	338	8	,	,	PUNCT
fnp-2819	338	9	karamita	karamita	PROPN
fnp-2819	338	10	,	,	PUNCT
fnp-2819	338	11	m.	m.	NOUN
fnp-2819	338	12	,	,	PUNCT
fnp-2819	338	13	vamvakas	vamvakas	PROPN
fnp-2819	338	14	,	,	PUNCT
fnp-2819	338	15	s.s	s.s	PROPN
fnp-2819	338	16	.	.	PROPN
fnp-2819	338	17	,	,	PUNCT
fnp-2819	338	18	szymkowski	szymkowski	PROPN
fnp-2819	338	19	,	,	PUNCT
fnp-2819	338	20	d.e	d.e	PROPN
fnp-2819	338	21	.	.	PROPN
fnp-2819	338	22	,	,	PUNCT
fnp-2819	338	23	probert	probert	PROPN
fnp-2819	338	24	,	,	PUNCT
fnp-2819	338	25	l.	l.	PROPN
fnp-2819	338	26	,	,	PUNCT
fnp-2819	338	27	2014	2014	NUM
fnp-2819	338	28	.	.	PUNCT
fnp-2819	339	1	altered	alter	VERB
fnp-2819	339	2	expression	expression	NOUN
fnp-2819	339	3	of	of	ADP
fnp-2819	339	4	oligodendrocyte	oligodendrocyte	ADJ
fnp-2819	339	5	and	and	CCONJ
fnp-2819	339	6	neuronal	neuronal	ADJ
fnp-2819	339	7	marker	marker	NOUN
fnp-2819	339	8	genes	gene	NOUN
fnp-2819	339	9	predicts	predict	VERB
fnp-2819	339	10	the	the	DET
fnp-2819	339	11	clinical	clinical	ADJ
fnp-2819	339	12	onset	onset	NOUN
fnp-2819	339	13	of	of	ADP
fnp-2819	339	14	autoimmune	autoimmune	ADJ
fnp-2819	339	15	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	339	16	and	and	CCONJ
fnp-2819	339	17	indicates	indicate	VERB
fnp-2819	339	18	the	the	DET
fnp-2819	339	19	effectiveness	effectiveness	NOUN
fnp-2819	339	20	of	of	ADP
fnp-2819	339	21	multiple	multiple	ADJ
fnp-2819	339	22	sclerosis	sclerosis	NOUN
fnp-2819	339	23	-	-	PUNCT
fnp-2819	339	24	directed	direct	VERB
fnp-2819	339	25	therapeutics	therapeutic	NOUN
fnp-2819	339	26	.	.	PUNCT
fnp-2819	340	1	j.	j.	PROPN
fnp-2819	340	2	immunol	immunol	PROPN
fnp-2819	340	3	.	.	PUNCT
fnp-2819	341	1	192	192	NUM
fnp-2819	341	2	,	,	PUNCT
fnp-2819	341	3	4122	4122	NUM
fnp-2819	341	4	-	-	SYM
fnp-2819	341	5	3133	3133	NUM
fnp-2819	341	6	.	.	PUNCT
fnp-2819	342	1	https://doi.org.10.4049	https://doi.org.10.4049	PROPN
fnp-2819	342	2	/	/	SYM
fnp-2819	342	3	jimmunol.1300633	jimmunol.1300633	PROPN
fnp-2819	342	4	.	.	PUNCT
fnp-2819	342	5	falcone	falcone	PROPN
fnp-2819	342	6	,	,	PUNCT
fnp-2819	342	7	m.	m.	NOUN
fnp-2819	342	8	,	,	PUNCT
fnp-2819	342	9	rajan	rajan	PROPN
fnp-2819	342	10	,	,	PUNCT
fnp-2819	342	11	a.j	a.j	PROPN
fnp-2819	342	12	.	.	PROPN
fnp-2819	342	13	,	,	PUNCT
fnp-2819	342	14	bloom	bloom	PROPN
fnp-2819	342	15	,	,	PUNCT
fnp-2819	342	16	b.r	b.r	PROPN
fnp-2819	342	17	.	.	PROPN
fnp-2819	342	18	,	,	PUNCT
fnp-2819	342	19	brosnan	brosnan	PROPN
fnp-2819	342	20	,	,	PUNCT
fnp-2819	342	21	c.f	c.f	PROPN
fnp-2819	342	22	.	.	PROPN
fnp-2819	342	23	,	,	PUNCT
fnp-2819	342	24	1998	1998	NUM
fnp-2819	342	25	.	.	PUNCT
fnp-2819	343	1	a	a	DET
fnp-2819	343	2	critical	critical	ADJ
fnp-2819	343	3	role	role	NOUN
fnp-2819	343	4	for	for	ADP
fnp-2819	343	5	il-4	il-4	NOUN
fnp-2819	343	6	in	in	ADP
fnp-2819	343	7	regulating	regulate	VERB
fnp-2819	343	8	disease	disease	NOUN
fnp-2819	343	9	severity	severity	NOUN
fnp-2819	343	10	in	in	ADP
fnp-2819	343	11	experimental	experimental	ADJ
fnp-2819	343	12	allergic	allergic	ADJ
fnp-2819	343	13	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	343	14	as	as	SCONJ
fnp-2819	343	15	demonstrated	demonstrate	VERB
fnp-2819	343	16	in	in	ADP
fnp-2819	343	17	il-4	il-4	NOUN
fnp-2819	343	18	-	-	PUNCT
fnp-2819	343	19	deficient	deficient	ADJ
fnp-2819	343	20	c57bl/6	c57bl/6	NOUN
fnp-2819	343	21	mice	mouse	NOUN
fnp-2819	343	22	and	and	CCONJ
fnp-2819	343	23	balb	balb	VERB
fnp-2819	343	24	/	/	SYM
fnp-2819	343	25	c	c	NOUN
fnp-2819	343	26	mice	mouse	NOUN
fnp-2819	343	27	.	.	PUNCT
fnp-2819	344	1	j.	j.	PROPN
fnp-2819	344	2	immunol	immunol	PROPN
fnp-2819	344	3	.	.	PUNCT
fnp-2819	345	1	160	160	NUM
fnp-2819	345	2	,	,	PUNCT
fnp-2819	345	3	4822–4830	4822–4830	NUM
fnp-2819	345	4	.	.	PUNCT
fnp-2819	346	1	pmid:9590229	pmid:9590229	PROPN
fnp-2819	346	2	.	.	PROPN
fnp-2819	346	3	faraco	faraco	PROPN
fnp-2819	346	4	,	,	PUNCT
fnp-2819	346	5	g.	g.	PROPN
fnp-2819	346	6	,	,	PUNCT
fnp-2819	346	7	cavone	cavone	NOUN
fnp-2819	346	8	l.	l.	PROPN
fnp-2819	346	9	,	,	PUNCT
fnp-2819	346	10	chiarugi	chiarugi	NOUN
fnp-2819	346	11	.	.	PROPN
fnp-2819	346	12	,	,	PUNCT
fnp-2819	346	13	2011	2011	NUM
fnp-2819	346	14	.	.	PUNCT
fnp-2819	347	1	the	the	DET
fnp-2819	347	2	therapeutic	therapeutic	ADJ
fnp-2819	347	3	potential	potential	NOUN
fnp-2819	347	4	of	of	ADP
fnp-2819	347	5	hdac	hdac	NOUN
fnp-2819	347	6	inhibitors	inhibitor	NOUN
fnp-2819	347	7	in	in	ADP
fnp-2819	347	8	the	the	DET
fnp-2819	347	9	treatment	treatment	NOUN
fnp-2819	347	10	of	of	ADP
fnp-2819	347	11	multiple	multiple	ADJ
fnp-2819	347	12	sclerosis	sclerosis	NOUN
fnp-2819	347	13	.	.	PUNCT
fnp-2819	348	1	mol	mol	PROPN
fnp-2819	348	2	.	.	PROPN
fnp-2819	348	3	med	med	PROPN
fnp-2819	348	4	.	.	PROPN
fnp-2819	349	1	17	17	NUM
fnp-2819	349	2	,	,	PUNCT
fnp-2819	349	3	442	442	NUM
fnp-2819	349	4	-	-	SYM
fnp-2819	349	5	447	447	NUM
fnp-2819	349	6	.	.	PUNCT
fnp-2819	350	1	pmid	pmid	PROPN
fnp-2819	350	2	21373721	21373721	NUM
fnp-2819	350	3	.	.	PUNCT
fnp-2819	351	1	ferber	ferber	PROPN
fnp-2819	351	2	,	,	PUNCT
fnp-2819	351	3	i.a	i.a	PROPN
fnp-2819	351	4	.	.	PROPN
fnp-2819	351	5	,	,	PUNCT
fnp-2819	351	6	brocke	brocke	PROPN
fnp-2819	351	7	,	,	PUNCT
fnp-2819	351	8	s.	s.	PROPN
fnp-2819	351	9	,	,	PUNCT
fnp-2819	351	10	taylor	taylor	PROPN
fnp-2819	351	11	-	-	PUNCT
fnp-2819	351	12	edwards	edwards	PROPN
fnp-2819	351	13	,	,	PUNCT
fnp-2819	351	14	c.	c.	PROPN
fnp-2819	351	15	,	,	PUNCT
fnp-2819	351	16	ridgway	ridgway	PROPN
fnp-2819	351	17	,	,	PUNCT
fnp-2819	351	18	w.	w.	PROPN
fnp-2819	351	19	,	,	PUNCT
fnp-2819	351	20	dinisco	dinisco	PROPN
fnp-2819	351	21	,	,	PUNCT
fnp-2819	351	22	c.	c.	PROPN
fnp-2819	351	23	,	,	PUNCT
fnp-2819	351	24	steinman	steinman	PROPN
fnp-2819	351	25	,	,	PUNCT
fnp-2819	351	26	l.	l.	PROPN
fnp-2819	351	27	,	,	PUNCT
fnp-2819	351	28	dalton	dalton	PROPN
fnp-2819	351	29	,	,	PUNCT
fnp-2819	351	30	d.	d.	PROPN
fnp-2819	351	31	,	,	PUNCT
fnp-2819	351	32	fathman	fathman	PROPN
fnp-2819	351	33	,	,	PUNCT
fnp-2819	351	34	c.g	c.g	PROPN
fnp-2819	351	35	.	.	PROPN
fnp-2819	351	36	,	,	PUNCT
fnp-2819	351	37	1996	1996	NUM
fnp-2819	351	38	.	.	PUNCT
fnp-2819	352	1	mice	mouse	NOUN
fnp-2819	352	2	with	with	ADP
fnp-2819	352	3	a	a	DET
fnp-2819	352	4	disrupted	disrupt	VERB
fnp-2819	352	5	ifn	ifn	PROPN
fnp-2819	352	6	-	-	PUNCT
fnp-2819	352	7	gamma	gamma	NOUN
fnp-2819	352	8	gene	gene	NOUN
fnp-2819	352	9	are	be	AUX
fnp-2819	352	10	susceptible	susceptible	ADJ
fnp-2819	352	11	to	to	ADP
fnp-2819	352	12	the	the	DET
fnp-2819	352	13	induction	induction	NOUN
fnp-2819	352	14	of	of	ADP
fnp-2819	352	15	experimental	experimental	ADJ
fnp-2819	352	16	autoimmune	autoimmune	ADJ
fnp-2819	352	17	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	352	18	(	(	PUNCT
fnp-2819	352	19	eae	eae	PROPN
fnp-2819	352	20	)	)	PUNCT
fnp-2819	352	21	.	.	PUNCT
fnp-2819	353	1	j.	j.	PROPN
fnp-2819	353	2	immunol	immunol	PROPN
fnp-2819	353	3	.	.	PUNCT
fnp-2819	354	1	156	156	NUM
fnp-2819	354	2	,	,	PUNCT
fnp-2819	354	3	5	5	NUM
fnp-2819	354	4	-	-	SYM
fnp-2819	354	5	7	7	NUM
fnp-2819	354	6	.	.	NUM
fnp-2819	354	7	pmid:8598493	pmid:8598493	NOUN
fnp-2819	354	8	.	.	PUNCT
fnp-2819	354	9	fernando	fernando	PROPN
fnp-2819	354	10	,	,	PUNCT
fnp-2819	354	11	v.	v.	PROPN
fnp-2819	354	12	,	,	PUNCT
fnp-2819	354	13	omura	omura	PROPN
fnp-2819	354	14	,	,	PUNCT
fnp-2819	354	15	s.	s.	PROPN
fnp-2819	354	16	,	,	PUNCT
fnp-2819	354	17	sato	sato	PROPN
fnp-2819	354	18	,	,	PUNCT
fnp-2819	354	19	f.	f.	PROPN
fnp-2819	354	20	,	,	PUNCT
fnp-2819	354	21	kawai	kawai	PROPN
fnp-2819	354	22	,	,	PUNCT
fnp-2819	354	23	e.	e.	PROPN
fnp-2819	354	24	,	,	PUNCT
fnp-2819	354	25	martinez	martinez	PROPN
fnp-2819	354	26	,	,	PUNCT
fnp-2819	354	27	n.e	n.e	PROPN
fnp-2819	354	28	.	.	PROPN
fnp-2819	354	29	,	,	PUNCT
fnp-2819	354	30	elliott	elliott	PROPN
fnp-2819	354	31	,	,	PUNCT
fnp-2819	354	32	s.f	s.f	PROPN
fnp-2819	354	33	.	.	PROPN
fnp-2819	354	34	,	,	PUNCT
fnp-2819	354	35	yoh	yoh	PROPN
fnp-2819	354	36	,	,	PUNCT
fnp-2819	354	37	k.	k.	PROPN
fnp-2819	354	38	,	,	PUNCT
fnp-2819	354	39	takahashi	takahashi	PROPN
fnp-2819	354	40	,	,	PUNCT
fnp-2819	354	41	s.	s.	PROPN
fnp-2819	354	42	,	,	PUNCT
fnp-2819	354	43	tsunoda	tsunoda	PROPN
fnp-2819	354	44	,	,	PUNCT
fnp-2819	354	45	i.	i.	PROPN
fnp-2819	354	46	,	,	PUNCT
fnp-2819	354	47	2014	2014	NUM
fnp-2819	354	48	.	.	PUNCT
fnp-2819	355	1	regulation	regulation	NOUN
fnp-2819	355	2	of	of	ADP
fnp-2819	355	3	an	an	DET
fnp-2819	355	4	autoimmune	autoimmune	ADJ
fnp-2819	355	5	model	model	NOUN
fnp-2819	355	6	for	for	ADP
fnp-2819	355	7	multiple	multiple	ADJ
fnp-2819	355	8	sclerosis	sclerosis	NOUN
fnp-2819	355	9	in	in	ADP
fnp-2819	355	10	th2	th2	PROPN
fnp-2819	355	11	-	-	PUNCT
fnp-2819	355	12	biased	biased	ADJ
fnp-2819	355	13	gata3	gata3	NOUN
fnp-2819	355	14	transgenic	transgenic	NOUN
fnp-2819	355	15	mice	mouse	NOUN
fnp-2819	355	16	.	.	PUNCT
fnp-2819	356	1	int	int	NOUN
fnp-2819	356	2	.	.	PUNCT
fnp-2819	357	1	j.	j.	PROPN
fnp-2819	357	2	mol	mol	PROPN
fnp-2819	357	3	.	.	PUNCT
fnp-2819	358	1	sci	sci	PROPN
fnp-2819	358	2	.	.	PROPN
fnp-2819	358	3	15	15	NUM
fnp-2819	358	4	,	,	PUNCT
fnp-2819	358	5	1700	1700	NUM
fnp-2819	358	6	-	-	SYM
fnp-2819	358	7	1708	1708	NUM
fnp-2819	358	8	.	.	PUNCT
fnp-2819	359	1	https://doi.org.10.3390	https://doi.org.10.3390	PROPN
fnp-2819	359	2	/	/	SYM
fnp-2819	359	3	ijms15021700	ijms15021700	PROPN
fnp-2819	359	4	.	.	PUNCT
fnp-2819	360	1	fox	fox	PROPN
fnp-2819	360	2	,	,	PUNCT
fnp-2819	360	3	r.j	r.j	PROPN
fnp-2819	360	4	.	.	PROPN
fnp-2819	360	5	,	,	PUNCT
fnp-2819	360	6	chataway	chataway	PROPN
fnp-2819	360	7	,	,	PUNCT
fnp-2819	360	8	j.	j.	PROPN
fnp-2819	360	9	,	,	PUNCT
fnp-2819	360	10	2017	2017	NUM
fnp-2819	360	11	.	.	PUNCT
fnp-2819	361	1	advancing	advance	VERB
fnp-2819	361	2	trial	trial	NOUN
fnp-2819	361	3	design	design	NOUN
fnp-2819	361	4	in	in	ADP
fnp-2819	361	5	progressive	progressive	ADJ
fnp-2819	361	6	multiple	multiple	ADJ
fnp-2819	361	7	sclerosis	sclerosis	NOUN
fnp-2819	361	8	.	.	PUNCT
fnp-2819	362	1	mult	mult	PROPN
fnp-2819	362	2	.	.	PROPN
fnp-2819	362	3	scler	scler	PROPN
fnp-2819	362	4	.	.	PUNCT
fnp-2819	363	1	23	23	NUM
fnp-2819	363	2	,	,	PUNCT
fnp-2819	363	3	1573	1573	NUM
fnp-2819	363	4	-	-	SYM
fnp-2819	363	5	1578	1578	NUM
fnp-2819	363	6	.	.	PUNCT
fnp-2819	364	1	https://doi.org.10.1177/1352458517729768	https://doi.org.10.1177/1352458517729768	NOUN
fnp-2819	364	2	göbel	göbel	PROPN
fnp-2819	364	3	,	,	PUNCT
fnp-2819	364	4	k.	k.	PROPN
fnp-2819	364	5	,	,	PUNCT
fnp-2819	364	6	ruck	ruck	NOUN
fnp-2819	364	7	,	,	PUNCT
fnp-2819	364	8	t.	t.	PROPN
fnp-2819	364	9	,	,	PUNCT
fnp-2819	364	10	meuth	meuth	PROPN
fnp-2819	364	11	,	,	PUNCT
fnp-2819	364	12	s.g	s.g	PROPN
fnp-2819	364	13	.	.	PROPN
fnp-2819	364	14	,	,	PUNCT
fnp-2819	364	15	2018	2018	NUM
fnp-2819	364	16	.	.	PUNCT
fnp-2819	365	1	cytokine	cytokine	NOUN
fnp-2819	365	2	signaling	signal	VERB
fnp-2819	365	3	in	in	ADP
fnp-2819	365	4	multiple	multiple	ADJ
fnp-2819	365	5	sclerosis	sclerosis	NOUN
fnp-2819	365	6	:	:	PUNCT
fnp-2819	365	7	lost	lose	VERB
fnp-2819	365	8	in	in	ADP
fnp-2819	365	9	translation	translation	NOUN
fnp-2819	365	10	.	.	PUNCT
fnp-2819	366	1	mult	mult	PROPN
fnp-2819	366	2	.	.	PROPN
fnp-2819	366	3	scler	scler	PROPN
fnp-2819	366	4	.	.	PUNCT
fnp-2819	367	1	24	24	NUM
fnp-2819	367	2	,	,	PUNCT
fnp-2819	367	3	432	432	NUM
fnp-2819	367	4	-	-	SYM
fnp-2819	367	5	439	439	NUM
fnp-2819	367	6	.	.	PUNCT
fnp-2819	368	1	https://doi.org.10.1177/1352458518763094	https://doi.org.10.1177/1352458518763094	X
fnp-2819	368	2	.	.	PUNCT
fnp-2819	369	1	goldberg	goldberg	PROPN
fnp-2819	369	2	,	,	PUNCT
fnp-2819	369	3	r.	r.	PROPN
fnp-2819	369	4	,	,	PUNCT
fnp-2819	369	5	wildbaum	wildbaum	NOUN
fnp-2819	369	6	,	,	PUNCT
fnp-2819	369	7	g.	g.	PROPN
fnp-2819	369	8	,	,	PUNCT
fnp-2819	369	9	zohar	zohar	PROPN
fnp-2819	369	10	,	,	PUNCT
fnp-2819	369	11	y.	y.	PROPN
fnp-2819	369	12	,	,	PUNCT
fnp-2819	369	13	maor	maor	PROPN
fnp-2819	369	14	,	,	PUNCT
fnp-2819	369	15	g.	g.	PROPN
fnp-2819	369	16	,	,	PUNCT
fnp-2819	369	17	karin	karin	PROPN
fnp-2819	369	18	,	,	PUNCT
fnp-2819	369	19	n.	n.	PROPN
fnp-2819	369	20	,	,	PUNCT
fnp-2819	369	21	2004	2004	NUM
fnp-2819	369	22	.	.	PUNCT
fnp-2819	370	1	suppression	suppression	NOUN
fnp-2819	370	2	of	of	ADP
fnp-2819	370	3	ongoing	ongoing	ADJ
fnp-2819	370	4	experimental	experimental	ADJ
fnp-2819	370	5	autoimmune	autoimmune	ADJ
fnp-2819	370	6	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	370	7	by	by	ADP
fnp-2819	370	8	neutralizing	neutralize	VERB
fnp-2819	370	9	the	the	DET
fnp-2819	370	10	function	function	NOUN
fnp-2819	370	11	of	of	ADP
fnp-2819	370	12	the	the	DET
fnp-2819	370	13	p28	p28	NOUN
fnp-2819	370	14	subunit	subunit	NOUN
fnp-2819	370	15	of	of	ADP
fnp-2819	370	16	il-27	il-27	NUM
fnp-2819	370	17	.	.	PUNCT
fnp-2819	371	1	j.	j.	PROPN
fnp-2819	371	2	immunol	immunol	PROPN
fnp-2819	371	3	.	.	PUNCT
fnp-2819	372	1	173	173	NUM
fnp-2819	372	2	,	,	PUNCT
fnp-2819	372	3	6465	6465	NUM
fnp-2819	372	4	-	-	SYM
fnp-2819	372	5	6471	6471	NUM
fnp-2819	372	6	.	.	PUNCT
fnp-2819	373	1	https://doi.org.10.4049	https://doi.org.10.4049	PROPN
fnp-2819	373	2	/	/	SYM
fnp-2819	373	3	jimmunol.173.10.6465	jimmunol.173.10.6465	NOUN
fnp-2819	373	4	.	.	PUNCT
fnp-2819	374	1	göschl	göschl	ADJ
fnp-2819	374	2	,	,	PUNCT
fnp-2819	374	3	l.	l.	PROPN
fnp-2819	374	4	,	,	PUNCT
fnp-2819	374	5	preglej	preglej	NOUN
fnp-2819	374	6	,	,	PUNCT
fnp-2819	374	7	t.	t.	PROPN
fnp-2819	374	8	,	,	PUNCT
fnp-2819	374	9	hamminger	hamminger	NOUN
fnp-2819	374	10	,	,	PUNCT
fnp-2819	374	11	p.	p.	PROPN
fnp-2819	374	12	,	,	PUNCT
fnp-2819	374	13	bonelli	bonelli	PROPN
fnp-2819	374	14	,	,	PUNCT
fnp-2819	374	15	m.	m.	NOUN
fnp-2819	374	16	,	,	PUNCT
fnp-2819	374	17	andersen	andersen	PROPN
fnp-2819	374	18	,	,	PUNCT
fnp-2819	374	19	l.	l.	PROPN
fnp-2819	374	20	,	,	PUNCT
fnp-2819	374	21	boucheron	boucheron	PROPN
fnp-2819	374	22	,	,	PUNCT
fnp-2819	374	23	n.	n.	NOUN
fnp-2819	374	24	,	,	PUNCT
fnp-2819	374	25	gülich	gülich	PROPN
fnp-2819	374	26	,	,	PUNCT
fnp-2819	374	27	af	af	PROPN
fnp-2819	374	28	.	.	PROPN
fnp-2819	374	29	,	,	PUNCT
fnp-2819	374	30	müller	müller	PROPN
fnp-2819	374	31	,	,	PUNCT
fnp-2819	374	32	l.	l.	PROPN
fnp-2819	374	33	,	,	PUNCT
fnp-2819	374	34	saferding	saferding	NOUN
fnp-2819	374	35	,	,	PUNCT
fnp-2819	374	36	v.	v.	ADV
fnp-2819	374	37	,	,	PUNCT
fnp-2819	374	38	mufazalov	mufazalov	NOUN
fnp-2819	374	39	,	,	PUNCT
fnp-2819	374	40	ia	ia	PROPN
fnp-2819	374	41	.	.	PROPN
fnp-2819	374	42	,	,	PUNCT
fnp-2819	374	43	hirahara	hirahara	PROPN
fnp-2819	374	44	,	,	PUNCT
fnp-2819	374	45	k.	k.	PROPN
fnp-2819	374	46	,	,	PUNCT
fnp-2819	374	47	seiser	seiser	NOUN
fnp-2819	374	48	,	,	PUNCT
fnp-2819	374	49	c.	c.	PROPN
fnp-2819	374	50	,	,	PUNCT
fnp-2819	374	51	matthias	matthias	PROPN
fnp-2819	374	52	,	,	PUNCT
fnp-2819	374	53	p.	p.	NOUN
fnp-2819	374	54	,	,	PUNCT
fnp-2819	374	55	penz	penz	NOUN
fnp-2819	374	56	,	,	PUNCT
fnp-2819	374	57	t.	t.	PROPN
fnp-2819	374	58	,	,	PUNCT
fnp-2819	374	59	schuster	schuster	PROPN
fnp-2819	374	60	,	,	PUNCT
fnp-2819	374	61	m.	m.	NOUN
fnp-2819	374	62	,	,	PUNCT
fnp-2819	374	63	bock	bock	NOUN
fnp-2819	374	64	,	,	PUNCT
fnp-2819	374	65	c.	c.	NOUN
fnp-2819	374	66	,	,	PUNCT
fnp-2819	374	67	waisman	waisman	NOUN
fnp-2819	374	68	,	,	PUNCT
fnp-2819	374	69	a.	a.	NOUN
fnp-2819	374	70	,	,	PUNCT
fnp-2819	374	71	steiner	steiner	NOUN
fnp-2819	374	72	,	,	PUNCT
fnp-2819	374	73	g.	g.	PROPN
fnp-2819	374	74	,	,	PUNCT
fnp-2819	374	75	ellmeier	ellmeier	NOUN
fnp-2819	374	76	,	,	PUNCT
fnp-2819	374	77	w.	w.	PROPN
fnp-2819	374	78	,	,	PUNCT
fnp-2819	374	79	2018	2018	NUM
fnp-2819	374	80	.	.	PUNCT
fnp-2819	375	1	a	a	DET
fnp-2819	375	2	t	t	NOUN
fnp-2819	375	3	cell	cell	NOUN
fnp-2819	375	4	-	-	PUNCT
fnp-2819	375	5	specific	specific	ADJ
fnp-2819	375	6	deletion	deletion	NOUN
fnp-2819	375	7	of	of	ADP
fnp-2819	375	8	hdac1	hdac1	NOUN
fnp-2819	375	9	protects	protect	VERB
fnp-2819	375	10	against	against	ADP
fnp-2819	375	11	experimental	experimental	ADJ
fnp-2819	375	12	autoimmune	autoimmune	ADJ
fnp-2819	375	13	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	375	14	.	.	PUNCT
fnp-2819	376	1	j.	j.	PROPN
fnp-2819	376	2	autoimmun	autoimmun	PROPN
fnp-2819	376	3	.	.	PROPN
fnp-2819	377	1	86	86	NUM
fnp-2819	377	2	,	,	PUNCT
fnp-2819	377	3	51	51	NUM
fnp-2819	377	4	-	-	SYM
fnp-2819	377	5	61	61	NUM
fnp-2819	377	6	.	.	PUNCT
fnp-2819	378	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	378	2	/	/	SYM
fnp-2819	378	3	j.jaut.2017.09.008	j.jaut.2017.09.008	PROPN
fnp-2819	378	4	.	.	PUNCT
fnp-2819	379	1	gran	gran	PROPN
fnp-2819	379	2	,	,	PUNCT
fnp-2819	379	3	b.	b.	PROPN
fnp-2819	379	4	,	,	PUNCT
fnp-2819	379	5	zhang	zhang	PROPN
fnp-2819	379	6	,	,	PUNCT
fnp-2819	379	7	g.x	g.x	PROPN
fnp-2819	379	8	.	.	PROPN
fnp-2819	379	9	,	,	PUNCT
fnp-2819	379	10	rostami	rostami	PROPN
fnp-2819	379	11	,	,	PUNCT
fnp-2819	379	12	a.	a.	NOUN
fnp-2819	379	13	,	,	PUNCT
fnp-2819	379	14	2004	2004	NUM
fnp-2819	379	15	.	.	PUNCT
fnp-2819	380	1	role	role	NOUN
fnp-2819	380	2	of	of	ADP
fnp-2819	380	3	the	the	DET
fnp-2819	380	4	il-12	il-12	NOUN
fnp-2819	380	5	/	/	SYM
fnp-2819	380	6	il-23	il-23	NOUN
fnp-2819	380	7	system	system	NOUN
fnp-2819	380	8	in	in	ADP
fnp-2819	380	9	the	the	DET
fnp-2819	380	10	regulation	regulation	NOUN
fnp-2819	380	11	of	of	ADP
fnp-2819	380	12	t	t	NOUN
fnp-2819	380	13	-	-	PUNCT
fnp-2819	380	14	cell	cell	NOUN
fnp-2819	380	15	responses	response	NOUN
fnp-2819	380	16	in	in	ADP
fnp-2819	380	17	central	central	ADJ
fnp-2819	380	18	nervous	nervous	ADJ
fnp-2819	380	19	system	system	NOUN
fnp-2819	380	20	inflammatory	inflammatory	ADJ
fnp-2819	380	21	demyelination	demyelination	NOUN
fnp-2819	380	22	.	.	PUNCT
fnp-2819	381	1	crit	crit	PROPN
fnp-2819	381	2	.	.	PUNCT
fnp-2819	382	1	rev	rev	PROPN
fnp-2819	382	2	.	.	PROPN
fnp-2819	382	3	immunol	immunol	NOUN
fnp-2819	382	4	.	.	PUNCT
fnp-2819	383	1	24	24	NUM
fnp-2819	383	2	,	,	PUNCT
fnp-2819	383	3	111	111	NUM
fnp-2819	383	4	-	-	SYM
fnp-2819	383	5	128	128	NUM
fnp-2819	383	6	.	.	PUNCT
fnp-2819	383	7	pmid:15581393	pmid:15581393	NOUN
fnp-2819	383	8	.	.	PUNCT
fnp-2819	384	1	hidaka	hidaka	PROPN
fnp-2819	384	2	,	,	PUNCT
fnp-2819	384	3	y.	y.	PROPN
fnp-2819	384	4	,	,	PUNCT
fnp-2819	384	5	inaba	inaba	PROPN
fnp-2819	384	6	,	,	PUNCT
fnp-2819	384	7	y.	y.	PROPN
fnp-2819	384	8	,	,	PUNCT
fnp-2819	384	9	matsuda	matsuda	PROPN
fnp-2819	384	10	,	,	PUNCT
fnp-2819	384	11	k.	k.	PROPN
fnp-2819	384	12	,	,	PUNCT
fnp-2819	384	13	itoh	itoh	PROPN
fnp-2819	384	14	,	,	PUNCT
fnp-2819	384	15	m.	m.	NOUN
fnp-2819	384	16	,	,	PUNCT
fnp-2819	384	17	kaneyama	kaneyama	NOUN
fnp-2819	384	18	,	,	PUNCT
fnp-2819	384	19	t.	t.	PROPN
fnp-2819	384	20	,	,	PUNCT
fnp-2819	384	21	nakazawa	nakazawa	PROPN
fnp-2819	384	22	,	,	PUNCT
fnp-2819	384	23	y.	y.	PROPN
fnp-2819	384	24	,	,	PUNCT
fnp-2819	384	25	koh	koh	PROPN
fnp-2819	384	26	,	,	PUNCT
fnp-2819	384	27	c.s	c.s	PROPN
fnp-2819	384	28	.	.	PROPN
fnp-2819	384	29	,	,	PUNCT
fnp-2819	384	30	ichikawa	ichikawa	PROPN
fnp-2819	384	31	,	,	PUNCT
fnp-2819	384	32	m.	m.	NOUN
fnp-2819	384	33	,	,	PUNCT
fnp-2819	384	34	2014	2014	NUM
fnp-2819	384	35	.	.	PUNCT
fnp-2819	385	1	cytokine	cytokine	ADJ
fnp-2819	385	2	production	production	NOUN
fnp-2819	385	3	proﬁles	proﬁle	NOUN
fnp-2819	385	4	in	in	ADP
fnp-2819	385	5	chronic	chronic	ADJ
fnp-2819	385	6	relapsing	relapsing	NOUN
fnp-2819	385	7	-	-	PUNCT
fnp-2819	385	8	remitting	remit	VERB
fnp-2819	385	9	experimental	experimental	ADJ
fnp-2819	385	10	autoimmune	autoimmune	ADJ
fnp-2819	385	11	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	385	12	:	:	PUNCT
fnp-2819	385	13	ifn	ifn	PROPN
fnp-2819	385	14	-	-	PUNCT
fnp-2819	385	15	γ	γ	X
fnp-2819	385	16	and	and	CCONJ
fnp-2819	385	17	tnf	tnf	PROPN
fnp-2819	385	18	-	-	PUNCT
fnp-2819	385	19	α	α	PROPN
fnp-2819	385	20	are	be	AUX
fnp-2819	385	21	essential	essential	ADJ
fnp-2819	385	22	participants	participant	NOUN
fnp-2819	385	23	in	in	ADP
fnp-2819	385	24	the	the	DET
fnp-2819	385	25	ﬁrst	ﬁrst	ADJ
fnp-2819	385	26	attack	attack	NOUN
fnp-2819	385	27	but	but	CCONJ
fnp-2819	385	28	not	not	PART
fnp-2819	385	29	in	in	ADP
fnp-2819	385	30	the	the	DET
fnp-2819	385	31	relapse	relapse	NOUN
fnp-2819	385	32	.	.	PUNCT
fnp-2819	386	1	j.	j.	PROPN
fnp-2819	386	2	neurol	neurol	PROPN
fnp-2819	386	3	.	.	PUNCT
fnp-2819	387	1	sci	sci	PROPN
fnp-2819	387	2	.	.	PROPN
fnp-2819	387	3	340	340	NUM
fnp-2819	387	4	,	,	PUNCT
fnp-2819	387	5	117	117	NUM
fnp-2819	387	6	-	-	SYM
fnp-2819	387	7	122	122	NUM
fnp-2819	387	8	.	.	PUNCT
fnp-2819	388	1	https://doi.org/10.1016/j.jns.2014.02.039	https://doi.org/10.1016/j.jns.2014.02.039	PROPN
fnp-2819	388	2	.	.	PUNCT
fnp-2819	389	1	hori	hori	PROPN
fnp-2819	389	2	,	,	PUNCT
fnp-2819	389	3	s.	s.	PROPN
fnp-2819	389	4	,	,	PUNCT
fnp-2819	389	5	nomura	nomura	NOUN
fnp-2819	389	6	,	,	PUNCT
fnp-2819	389	7	t.	t.	PROPN
fnp-2819	389	8	,	,	PUNCT
fnp-2819	389	9	sakaguchi	sakaguchi	PROPN
fnp-2819	389	10	,	,	PUNCT
fnp-2819	389	11	s.	s.	PROPN
fnp-2819	389	12	,	,	PUNCT
fnp-2819	389	13	2003	2003	NUM
fnp-2819	389	14	.	.	PUNCT
fnp-2819	390	1	control	control	NOUN
fnp-2819	390	2	of	of	ADP
fnp-2819	390	3	regulatory	regulatory	ADJ
fnp-2819	390	4	t	t	PROPN
fnp-2819	390	5	cell	cell	NOUN
fnp-2819	390	6	development	development	NOUN
fnp-2819	390	7	by	by	ADP
fnp-2819	390	8	the	the	DET
fnp-2819	390	9	transcription	transcription	NOUN
fnp-2819	390	10	factor	factor	NOUN
fnp-2819	390	11	foxp3	foxp3	PROPN
fnp-2819	390	12	.	.	PUNCT
fnp-2819	391	1	science	science	PROPN
fnp-2819	391	2	299	299	NUM
fnp-2819	391	3	,	,	PUNCT
fnp-2819	391	4	1057	1057	NUM
fnp-2819	391	5	-	-	SYM
fnp-2819	391	6	1061	1061	NUM
fnp-2819	391	7	.	.	PUNCT
fnp-2819	392	1	https://doi.org.10.1126	https://doi.org.10.1126	NOUN
fnp-2819	392	2	/	/	SYM
fnp-2819	392	3	science.1079490	science.1079490	PROPN
fnp-2819	392	4	.	.	PROPN
fnp-2819	392	5	jayaraman	jayaraman	NOUN
fnp-2819	392	6	,	,	PUNCT
fnp-2819	392	7	s.	s.	PROPN
fnp-2819	392	8	,	,	PUNCT
fnp-2819	392	9	muthukkaruppan	muthukkaruppan	PROPN
fnp-2819	392	10	,	,	PUNCT
fnp-2819	392	11	v.r	v.r	PROPN
fnp-2819	392	12	.	.	PROPN
fnp-2819	392	13	,	,	PUNCT
fnp-2819	392	14	1977	1977	NUM
fnp-2819	392	15	.	.	PUNCT
fnp-2819	393	1	in	in	ADP
fnp-2819	393	2	vitro	vitro	X
fnp-2819	393	3	correlate	correlate	VERB
fnp-2819	393	4	of	of	ADP
fnp-2819	393	5	transplantation	transplantation	NOUN
fnp-2819	393	6	immunity	immunity	NOUN
fnp-2819	393	7	:	:	PUNCT
fnp-2819	393	8	spleen	spleen	NOUN
fnp-2819	393	9	cell	cell	NOUN
fnp-2819	393	10	migration	migration	NOUN
fnp-2819	393	11	inhibition	inhibition	NOUN
fnp-2819	393	12	in	in	ADP
fnp-2819	393	13	the	the	DET
fnp-2819	393	14	lizard	lizard	NOUN
fnp-2819	393	15	,	,	PUNCT
fnp-2819	393	16	calotes	calote	VERB
fnp-2819	393	17	versicolor	versicolor	NOUN
fnp-2819	393	18	.	.	PUNCT
fnp-2819	394	1	dev	dev	PROPN
fnp-2819	394	2	.	.	PUNCT
fnp-2819	395	1	comp	comp	PROPN
fnp-2819	395	2	.	.	PUNCT
fnp-2819	396	1	immunol	immunol	NOUN
fnp-2819	396	2	.	.	PUNCT
fnp-2819	397	1	1	1	NUM
fnp-2819	397	2	,	,	PUNCT
fnp-2819	397	3	133	133	NUM
fnp-2819	397	4	-	-	SYM
fnp-2819	397	5	143	143	NUM
fnp-2819	397	6	.	.	PUNCT
fnp-2819	398	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	398	2	/	/	SYM
fnp-2819	398	3	s0145	s0145	PROPN
fnp-2819	398	4	-	-	PUNCT
fnp-2819	398	5	305x(77)80006	305x(77)80006	NUM
fnp-2819	398	6	-	-	SYM
fnp-2819	398	7	2	2	NUM
fnp-2819	398	8	.	.	PUNCT
fnp-2819	399	1	jayaraman	jayaraman	NOUN
fnp-2819	399	2	,	,	PUNCT
fnp-2819	399	3	s.	s.	PROPN
fnp-2819	399	4	,	,	PUNCT
fnp-2819	399	5	luo	luo	PROPN
fnp-2819	399	6	,	,	PUNCT
fnp-2819	399	7	y.	y.	PROPN
fnp-2819	399	8	,	,	PUNCT
fnp-2819	399	9	dorf	dorf	PROPN
fnp-2819	399	10	,	,	PUNCT
fnp-2819	399	11	m.e	m.e	PROPN
fnp-2819	399	12	.	.	PROPN
fnp-2819	399	13	,	,	PUNCT
fnp-2819	399	14	1992	1992	NUM
fnp-2819	399	15	.	.	PUNCT
fnp-2819	400	1	tolerance	tolerance	NOUN
fnp-2819	400	2	induction	induction	NOUN
fnp-2819	400	3	in	in	ADP
fnp-2819	400	4	t	t	PROPN
fnp-2819	400	5	helper	helper	NOUN
fnp-2819	400	6	(	(	PUNCT
fnp-2819	400	7	th1	th1	NOUN
fnp-2819	400	8	)	)	PUNCT
fnp-2819	400	9	cells	cell	NOUN
fnp-2819	400	10	by	by	ADP
fnp-2819	400	11	thymic	thymic	ADJ
fnp-2819	400	12	macrophages	macrophage	NOUN
fnp-2819	400	13	.	.	PUNCT
fnp-2819	401	1	j.	j.	PROPN
fnp-2819	401	2	immunol	immunol	PROPN
fnp-2819	401	3	.	.	PUNCT
fnp-2819	402	1	148	148	NUM
fnp-2819	402	2	,	,	PUNCT
fnp-2819	402	3	2672	2672	NUM
fnp-2819	402	4	-	-	SYM
fnp-2819	402	5	2681	2681	NUM
fnp-2819	402	6	.	.	PUNCT
fnp-2819	403	1	pmid:1533409	pmid:1533409	NOUN
fnp-2819	403	2	.	.	PUNCT
fnp-2819	404	1	jayaraman	jayaraman	NOUN
fnp-2819	404	2	,	,	PUNCT
fnp-2819	404	3	s.	s.	PROPN
fnp-2819	404	4	,	,	PUNCT
fnp-2819	404	5	patel	patel	PROPN
fnp-2819	404	6	,	,	PUNCT
fnp-2819	404	7	t.	t.	PROPN
fnp-2819	404	8	,	,	PUNCT
fnp-2819	404	9	patel	patel	PROPN
fnp-2819	404	10	,	,	PUNCT
fnp-2819	404	11	v.	v.	ADV
fnp-2819	404	12	,	,	PUNCT
fnp-2819	404	13	garza	garza	PROPN
fnp-2819	404	14	,	,	PUNCT
fnp-2819	404	15	r.	r.	PROPN
fnp-2819	404	16	,	,	PUNCT
fnp-2819	404	17	ajani	ajani	PROPN
fnp-2819	404	18	,	,	PUNCT
fnp-2819	404	19	s.	s.	PROPN
fnp-2819	404	20	,	,	PUNCT
fnp-2819	404	21	jayaraman	jayaraman	NOUN
fnp-2819	404	22	,	,	PUNCT
fnp-2819	404	23	a.	a.	NOUN
fnp-2819	404	24	,	,	PUNCT
fnp-2819	404	25	singh	singh	PROPN
fnp-2819	404	26	,	,	PUNCT
fnp-2819	404	27	r.	r.	PROPN
fnp-2819	404	28	,	,	PUNCT
fnp-2819	404	29	kwon	kwon	PROPN
fnp-2819	404	30	,	,	PUNCT
fnp-2819	404	31	s.	s.	PROPN
fnp-2819	404	32	,	,	PUNCT
fnp-2819	404	33	rondelli	rondelli	PROPN
fnp-2819	404	34	,	,	PUNCT
fnp-2819	404	35	d.	d.	PROPN
fnp-2819	404	36	,	,	PUNCT
fnp-2819	404	37	prabhakar	prabhakar	PROPN
fnp-2819	404	38	,	,	PUNCT
fnp-2819	404	39	s.	s.	PROPN
fnp-2819	404	40	,	,	PUNCT
fnp-2819	404	41	holterman	holterman	NOUN
fnp-2819	404	42	,	,	PUNCT
fnp-2819	404	43	m.	m.	NOUN
fnp-2819	404	44	,	,	PUNCT
fnp-2819	404	45	2010	2010	NUM
fnp-2819	404	46	.	.	PUNCT
fnp-2819	405	1	transfusion	transfusion	NOUN
fnp-2819	405	2	of	of	ADP
fnp-2819	405	3	nonobese	nonobese	ADJ
fnp-2819	405	4	diabetic	diabetic	ADJ
fnp-2819	405	5	mice	mouse	NOUN
fnp-2819	405	6	with	with	ADP
fnp-2819	405	7	allogeneic	allogeneic	ADJ
fnp-2819	405	8	newborn	newborn	ADJ
fnp-2819	405	9	blood	blood	NOUN
fnp-2819	405	10	ameliorates	ameliorate	VERB
fnp-2819	405	11	autoimmune	autoimmune	ADJ
fnp-2819	405	12	diabetes	diabetes	NOUN
fnp-2819	405	13	and	and	CCONJ
fnp-2819	405	14	modifies	modify	VERB
fnp-2819	405	15	the	the	DET
fnp-2819	405	16	expression	expression	NOUN
fnp-2819	405	17	of	of	ADP
fnp-2819	405	18	selected	select	VERB
fnp-2819	405	19	immune	immune	ADJ
fnp-2819	405	20	response	response	NOUN
fnp-2819	405	21	genes	gene	NOUN
fnp-2819	405	22	.	.	PUNCT
fnp-2819	406	1	j.	j.	PROPN
fnp-2819	406	2	immunol	immunol	PROPN
fnp-2819	406	3	.	.	PUNCT
fnp-2819	407	1	184	184	NUM
fnp-2819	407	2	,	,	PUNCT
fnp-2819	407	3	3008	3008	NUM
fnp-2819	407	4	-	-	SYM
fnp-2819	407	5	3015	3015	NUM
fnp-2819	407	6	.	.	PUNCT
fnp-2819	408	1	pmid:20164427	pmid:20164427	NOUN
fnp-2819	408	2	.	.	PROPN
fnp-2819	408	3	jayaraman	jayaraman	PROPN
fnp-2819	408	4	,	,	PUNCT
fnp-2819	408	5	s.	s.	PROPN
fnp-2819	408	6	,	,	PUNCT
fnp-2819	408	7	patel	patel	PROPN
fnp-2819	408	8	,	,	PUNCT
fnp-2819	408	9	a.	a.	NOUN
fnp-2819	408	10	,	,	PUNCT
fnp-2819	408	11	jayaraman	jayaraman	NOUN
fnp-2819	408	12	,	,	PUNCT
fnp-2819	408	13	a.	a.	NOUN
fnp-2819	408	14	,	,	PUNCT
fnp-2819	408	15	patel	patel	PROPN
fnp-2819	408	16	,	,	PUNCT
fnp-2819	408	17	v.	v.	ADV
fnp-2819	408	18	,	,	PUNCT
fnp-2819	408	19	holterman	holterman	NOUN
fnp-2819	408	20	,	,	PUNCT
fnp-2819	408	21	m.	m.	NOUN
fnp-2819	408	22	,	,	PUNCT
fnp-2819	408	23	prabhakar	prabhakar	PROPN
fnp-2819	408	24	,	,	PUNCT
fnp-2819	408	25	b.	b.	PROPN
fnp-2819	408	26	,	,	PUNCT
fnp-2819	408	27	2013	2013	NUM
fnp-2819	408	28	.	.	PUNCT
fnp-2819	409	1	transcriptome	transcriptome	ADJ
fnp-2819	409	2	analysis	analysis	NOUN
fnp-2819	409	3	of	of	ADP
fnp-2819	409	4	epigenetically	epigenetically	ADV
fnp-2819	409	5	modulated	modulate	VERB
fnp-2819	409	6	genome	genome	NOUN
fnp-2819	409	7	indicates	indicate	VERB
fnp-2819	409	8	signature	signature	NOUN
fnp-2819	409	9	genes	gene	NOUN
fnp-2819	409	10	in	in	ADP
fnp-2819	409	11	manifestation	manifestation	NOUN
fnp-2819	409	12	of	of	ADP
fnp-2819	409	13	type	type	NOUN
fnp-2819	409	14	1	1	NUM
fnp-2819	409	15	diabetes	diabetes	NOUN
fnp-2819	409	16	and	and	CCONJ
fnp-2819	409	17	its	its	PRON
fnp-2819	409	18	prevention	prevention	NOUN
fnp-2819	409	19	in	in	ADP
fnp-2819	409	20	nod	nod	PROPN
fnp-2819	409	21	mice	mouse	NOUN
fnp-2819	409	22	.	.	PUNCT
fnp-2819	410	1	plos	plos	PROPN
fnp-2819	410	2	one	one	NUM
fnp-2819	410	3	8	8	NUM
fnp-2819	410	4	,	,	PUNCT
fnp-2819	410	5	e55074	e55074	NOUN
fnp-2819	410	6	.	.	PUNCT
fnp-2819	411	1	https://doi.org.10.1371	https://doi.org.10.1371	PROPN
fnp-2819	411	2	/	/	SYM
fnp-2819	411	3	journal.pone.0055074	journal.pone.0055074	PROPN
fnp-2819	411	4	.	.	PUNCT
fnp-2819	412	1	jayaraman	jayaraman	PROPN
fnp-2819	412	2	,	,	PUNCT
fnp-2819	412	3	a.	a.	PROPN
fnp-2819	412	4	,	,	PUNCT
fnp-2819	412	5	soni	soni	PROPN
fnp-2819	412	6	,	,	PUNCT
fnp-2819	412	7	a.	a.	PROPN
fnp-2819	412	8	,	,	PUNCT
fnp-2819	412	9	prabhakar	prabhakar	NOUN
fnp-2819	412	10	,	,	PUNCT
fnp-2819	412	11	b.s	b.s	PROPN
fnp-2819	412	12	.	.	PROPN
fnp-2819	412	13	,	,	PUNCT
fnp-2819	412	14	holterman	holterman	NOUN
fnp-2819	412	15	,	,	PUNCT
fnp-2819	412	16	m.	m.	NOUN
fnp-2819	412	17	,	,	PUNCT
fnp-2819	412	18	jayaraman	jayaraman	NOUN
fnp-2819	412	19	,	,	PUNCT
fnp-2819	412	20	s.	s.	PROPN
fnp-2819	412	21	,	,	PUNCT
fnp-2819	412	22	2017	2017	NUM
fnp-2819	412	23	.	.	PUNCT
fnp-2819	413	1	the	the	DET
fnp-2819	413	2	epigenetic	epigenetic	ADJ
fnp-2819	413	3	drug	drug	NOUN
fnp-2819	413	4	trichostatin	trichostatin	NOUN
fnp-2819	413	5	a	a	DET
fnp-2819	413	6	ameliorates	ameliorate	NOUN
fnp-2819	413	7	experimental	experimental	ADJ
fnp-2819	413	8	autoimmune	autoimmune	ADJ
fnp-2819	413	9	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	413	10	via	via	ADP
fnp-2819	413	11	t	t	PROPN
fnp-2819	413	12	cell	cell	NOUN
fnp-2819	413	13	tolerance	tolerance	NOUN
fnp-2819	413	14	induction	induction	NOUN
fnp-2819	413	15	and	and	CCONJ
fnp-2819	413	16	impaired	impaired	ADJ
fnp-2819	413	17	influx	influx	NOUN
fnp-2819	413	18	of	of	ADP
fnp-2819	413	19	t	t	PROPN
fnp-2819	413	20	cells	cell	NOUN
fnp-2819	413	21	into	into	ADP
fnp-2819	413	22	the	the	DET
fnp-2819	413	23	spinal	spinal	ADJ
fnp-2819	413	24	cord	cord	NOUN
fnp-2819	413	25	.	.	PUNCT
fnp-2819	414	1	neurobiol	neurobiol	PROPN
fnp-2819	414	2	.	.	PUNCT
fnp-2819	415	1	dis	dis	PROPN
fnp-2819	415	2	.	.	PUNCT
fnp-2819	416	1	108	108	NUM
fnp-2819	416	2	,	,	PUNCT
fnp-2819	416	3	1	1	NUM
fnp-2819	416	4	-	-	SYM
fnp-2819	416	5	12	12	NUM
fnp-2819	416	6	.	.	PUNCT
fnp-2819	417	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	417	2	/	/	SYM
fnp-2819	417	3	j.nbd.2017.07.015	j.nbd.2017.07.015	PROPN
fnp-2819	417	4	.	.	PUNCT
fnp-2819	418	1	jayaraman	jayaraman	NOUN
fnp-2819	418	2	,	,	PUNCT
fnp-2819	418	3	a.	a.	PROPN
fnp-2819	418	4	,	,	PUNCT
fnp-2819	418	5	sharma	sharma	PROPN
fnp-2819	418	6	,	,	PUNCT
fnp-2819	418	7	m.	m.	NOUN
fnp-2819	418	8	,	,	PUNCT
fnp-2819	418	9	prabhakar	prabhakar	PROPN
fnp-2819	418	10	,	,	PUNCT
fnp-2819	418	11	b.	b.	PROPN
fnp-2819	418	12	,	,	PUNCT
fnp-2819	418	13	holterman	holterman	NOUN
fnp-2819	418	14	,	,	PUNCT
fnp-2819	418	15	m.	m.	NOUN
fnp-2819	418	16	,	,	PUNCT
fnp-2819	418	17	jayaraman	jayaraman	NOUN
fnp-2819	418	18	,	,	PUNCT
fnp-2819	418	19	s.	s.	PROPN
fnp-2819	418	20	,	,	PUNCT
fnp-2819	418	21	2018	2018	NUM
fnp-2819	418	22	.	.	PUNCT
fnp-2819	419	1	amelioration	amelioration	NOUN
fnp-2819	419	2	of	of	ADP
fnp-2819	419	3	progressive	progressive	ADJ
fnp-2819	419	4	autoimmune	autoimmune	ADJ
fnp-2819	419	5	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	419	6	by	by	ADP
fnp-2819	419	7	epigenetic	epigenetic	ADJ
fnp-2819	419	8	regulation	regulation	NOUN
fnp-2819	419	9	involves	involve	VERB
fnp-2819	419	10	selective	selective	ADJ
fnp-2819	419	11	repression	repression	NOUN
fnp-2819	419	12	of	of	ADP
fnp-2819	419	13	mature	mature	ADJ
fnp-2819	419	14	neutrophils	neutrophil	NOUN
fnp-2819	419	15	during	during	ADP
fnp-2819	419	16	the	the	DET
fnp-2819	419	17	preclinical	preclinical	ADJ
fnp-2819	419	18	phase	phase	NOUN
fnp-2819	419	19	.	.	PUNCT
fnp-2819	420	1	exp	exp	NOUN
fnp-2819	420	2	.	.	PUNCT
fnp-2819	421	1	neurol	neurol	PROPN
fnp-2819	421	2	.	.	PUNCT
fnp-2819	422	1	304	304	NUM
fnp-2819	422	2	,	,	PUNCT
fnp-2819	422	3	14	14	NUM
fnp-2819	422	4	-	-	SYM
fnp-2819	422	5	20	20	NUM
fnp-2819	422	6	.	.	PUNCT
fnp-2819	423	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	423	2	/	/	SYM
fnp-2819	423	3	j.expneurol.2018.02.008	j.expneurol.2018.02.008	PROPN
fnp-2819	423	4	.	.	PUNCT
fnp-2819	424	1	jayaraman	jayaraman	PROPN
fnp-2819	424	2	,	,	PUNCT
fnp-2819	424	3	s.	s.	PROPN
fnp-2819	424	4	,	,	PUNCT
fnp-2819	424	5	jayaraman	jayaraman	NOUN
fnp-2819	424	6	,	,	PUNCT
fnp-2819	424	7	a.	a.	NOUN
fnp-2819	424	8	,	,	PUNCT
fnp-2819	424	9	2018	2018	NUM
fnp-2819	424	10	.	.	PUNCT
fnp-2819	425	1	long	long	ADJ
fnp-2819	425	2	-	-	PUNCT
fnp-2819	425	3	term	term	NOUN
fnp-2819	425	4	provision	provision	NOUN
fnp-2819	425	5	of	of	ADP
fnp-2819	425	6	acidified	acidify	VERB
fnp-2819	425	7	drinking	drinking	NOUN
fnp-2819	425	8	water	water	NOUN
fnp-2819	425	9	fails	fail	VERB
fnp-2819	425	10	to	to	PART
fnp-2819	425	11	influence	influence	VERB
fnp-2819	425	12	autoimmune	autoimmune	ADJ
fnp-2819	425	13	diabetes	diabetes	NOUN
fnp-2819	425	14	and	and	CCONJ
fnp-2819	425	15	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	425	16	.	.	PUNCT
fnp-2819	426	1	j.	j.	PROPN
fnp-2819	426	2	diab	diab	PROPN
fnp-2819	426	3	.	.	PUNCT
fnp-2819	427	1	res	re	NOUN
fnp-2819	427	2	.	.	PUNCT
fnp-2819	428	1	2018:3424691	2018:3424691	NUM
fnp-2819	428	2	.	.	PUNCT
fnp-2819	428	3	pmid:30035128	pmid:30035128	NOUN
fnp-2819	428	4	.	.	PUNCT
fnp-2819	429	1	jayaraman	jayaraman	NOUN
fnp-2819	429	2	,	,	PUNCT
fnp-2819	429	3	s.	s.	PROPN
fnp-2819	429	4	,	,	PUNCT
fnp-2819	429	5	prabhakar	prabhakar	PROPN
fnp-2819	429	6	,	,	PUNCT
fnp-2819	429	7	b.s	b.s	PROPN
fnp-2819	429	8	.	.	PROPN
fnp-2819	429	9	,	,	PUNCT
fnp-2819	429	10	2019	2019	NUM
fnp-2819	429	11	.	.	PUNCT
fnp-2819	430	1	immune	immune	ADJ
fnp-2819	430	2	tolerance	tolerance	NOUN
fnp-2819	430	3	in	in	ADP
fnp-2819	430	4	autoimmune	autoimmune	ADJ
fnp-2819	430	5	central	central	ADJ
fnp-2819	430	6	nervous	nervous	ADJ
fnp-2819	430	7	system	system	NOUN
fnp-2819	430	8	disorders	disorder	NOUN
fnp-2819	430	9	.	.	PUNCT
fnp-2819	431	1	in	in	ADP
fnp-2819	431	2	:	:	PUNCT
fnp-2819	431	3	mitoma	mitoma	PROPN
fnp-2819	431	4	,	,	PUNCT
fnp-2819	431	5	h.	h.	PROPN
fnp-2819	431	6	,	,	PUNCT
fnp-2819	431	7	manto	manto	PROPN
fnp-2819	431	8	,	,	PUNCT
fnp-2819	431	9	m.	m.	NOUN
fnp-2819	431	10	,	,	PUNCT
fnp-2819	431	11	(	(	PUNCT
fnp-2819	431	12	eds	ed	NOUN
fnp-2819	431	13	.	.	PUNCT
fnp-2819	431	14	)	)	PUNCT
fnp-2819	431	15	autoimmune	autoimmune	ADJ
fnp-2819	431	16	central	central	ADJ
fnp-2819	431	17	nervous	nervous	ADJ
fnp-2819	431	18	disorders	disorder	NOUN
fnp-2819	431	19	.	.	PUNCT
fnp-2819	432	1	springer	springer	NOUN
fnp-2819	432	2	nature	nature	PROPN
fnp-2819	432	3	,	,	PUNCT
fnp-2819	432	4	london	london	PROPN
fnp-2819	432	5	,	,	PUNCT
fnp-2819	432	6	pp.143	pp.143	NOUN
fnp-2819	432	7	-	-	PUNCT
fnp-2819	432	8	166	166	NUM
fnp-2819	432	9	.	.	PUNCT
fnp-2819	433	1	https://doi.org.10.1007/978	https://doi.org.10.1007/978	NOUN
fnp-2819	433	2	-	-	PUNCT
fnp-2819	433	3	3	3	NUM
fnp-2819	433	4	-	-	PUNCT
fnp-2819	433	5	030	030	NUM
fnp-2819	433	6	-	-	PUNCT
fnp-2819	433	7	19515	19515	NUM
fnp-2819	433	8	-	-	SYM
fnp-2819	433	9	1_5	1_5	NUM
fnp-2819	433	10	.	.	PUNCT
fnp-2819	434	1	kandagaddala	kandagaddala	PROPN
fnp-2819	434	2	,	,	PUNCT
fnp-2819	434	3	l.d	l.d	PROPN
fnp-2819	434	4	.	.	PROPN
fnp-2819	434	5	,	,	PUNCT
fnp-2819	434	6	kang	kang	PROPN
fnp-2819	434	7	,	,	PUNCT
fnp-2819	434	8	m.j	m.j	PROPN
fnp-2819	434	9	.	.	PROPN
fnp-2819	434	10	,	,	PUNCT
fnp-2819	434	11	chung	chung	PROPN
fnp-2819	434	12	,	,	PUNCT
fnp-2819	434	13	b.c	b.c	PROPN
fnp-2819	434	14	.	.	PROPN
fnp-2819	434	15	,	,	PUNCT
fnp-2819	434	16	patterson	patterson	PROPN
fnp-2819	434	17	,	,	PUNCT
fnp-2819	434	18	t.a	t.a	PROPN
fnp-2819	434	19	.	.	PROPN
fnp-2819	434	20	,	,	PUNCT
fnp-2819	434	21	kwon	kwon	PROPN
fnp-2819	434	22	,	,	PUNCT
fnp-2819	434	23	o.s	o.s	PROPN
fnp-2819	434	24	.	.	PROPN
fnp-2819	434	25	,	,	PUNCT
fnp-2819	434	26	2012	2012	NUM
fnp-2819	434	27	.	.	PUNCT
fnp-2819	435	1	expression	expression	NOUN
fnp-2819	435	2	and	and	CCONJ
fnp-2819	435	3	activation	activation	NOUN
fnp-2819	435	4	of	of	ADP
fnp-2819	435	5	matrix	matrix	NOUN
fnp-2819	435	6	metalloproteinase-9	metalloproteinase-9	NUM
fnp-2819	435	7	and	and	CCONJ
fnp-2819	435	8	nadph	nadph	ADJ
fnp-2819	435	9	oxidase	oxidase	NOUN
fnp-2819	435	10	in	in	ADP
fnp-2819	435	11	tissues	tissue	NOUN
fnp-2819	435	12	and	and	CCONJ
fnp-2819	435	13	plasma	plasma	NOUN
fnp-2819	435	14	of	of	ADP
fnp-2819	435	15	experimental	experimental	ADJ
fnp-2819	435	16	autoimmune	autoimmune	ADJ
fnp-2819	435	17	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	435	18	in	in	ADP
fnp-2819	435	19	mice	mouse	NOUN
fnp-2819	435	20	.	.	PUNCT
fnp-2819	436	1	exp	exp	PROPN
fnp-2819	436	2	.	.	PUNCT
fnp-2819	437	1	toxicol	toxicol	PROPN
fnp-2819	437	2	.	.	PUNCT
fnp-2819	438	1	pathol	pathol	PROPN
fnp-2819	438	2	.	.	PUNCT
fnp-2819	439	1	64	64	NUM
fnp-2819	439	2	,	,	PUNCT
fnp-2819	439	3	109	109	NUM
fnp-2819	439	4	-	-	SYM
fnp-2819	439	5	114	114	NUM
fnp-2819	439	6	.	.	PUNCT
fnp-2819	440	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	440	2	/	/	SYM
fnp-2819	440	3	j.etp.2010.07.002	j.etp.2010.07.002	NOUN
fnp-2819	440	4	.	.	PUNCT
fnp-2819	441	1	kreymborg	kreymborg	PROPN
fnp-2819	441	2	,	,	PUNCT
fnp-2819	441	3	k.	k.	PROPN
fnp-2819	441	4	,	,	PUNCT
fnp-2819	441	5	etzensperger	etzensperger	PROPN
fnp-2819	441	6	,	,	PUNCT
fnp-2819	441	7	r.	r.	PROPN
fnp-2819	441	8	,	,	PUNCT
fnp-2819	441	9	dumoutier	dumoutier	NOUN
fnp-2819	441	10	,	,	PUNCT
fnp-2819	441	11	l.	l.	PROPN
fnp-2819	441	12	,	,	PUNCT
fnp-2819	441	13	haak	haak	PROPN
fnp-2819	441	14	,	,	PUNCT
fnp-2819	441	15	s.	s.	PROPN
fnp-2819	441	16	,	,	PUNCT
fnp-2819	441	17	rebollo	rebollo	PROPN
fnp-2819	441	18	,	,	PUNCT
fnp-2819	441	19	a.	a.	NOUN
fnp-2819	441	20	,	,	PUNCT
fnp-2819	441	21	buch	buch	NOUN
fnp-2819	441	22	,	,	PUNCT
fnp-2819	441	23	t.	t.	PROPN
fnp-2819	441	24	,	,	PUNCT
fnp-2819	441	25	heppner	heppner	PROPN
fnp-2819	441	26	,	,	PUNCT
fnp-2819	441	27	f.l	f.l	PROPN
fnp-2819	441	28	.	.	PROPN
fnp-2819	441	29	,	,	PUNCT
fnp-2819	441	30	renauld	renauld	AUX
fnp-2819	441	31	,	,	PUNCT
fnp-2819	441	32	j.c	j.c	PROPN
fnp-2819	441	33	.	.	PROPN
fnp-2819	441	34	,	,	PUNCT
fnp-2819	441	35	becher	becher	PROPN
fnp-2819	441	36	,	,	PUNCT
fnp-2819	441	37	b.	b.	PROPN
fnp-2819	441	38	,	,	PUNCT
fnp-2819	441	39	2007	2007	NUM
fnp-2819	441	40	.	.	PUNCT
fnp-2819	442	1	il-22	il-22	X
fnp-2819	442	2	is	be	AUX
fnp-2819	442	3	expressed	express	VERB
fnp-2819	442	4	by	by	ADP
fnp-2819	442	5	th17	th17	NOUN
fnp-2819	442	6	cells	cell	NOUN
fnp-2819	442	7	in	in	ADP
fnp-2819	442	8	an	an	DET
fnp-2819	442	9	il-23	il-23	NOUN
fnp-2819	442	10	-	-	PUNCT
fnp-2819	442	11	dependent	dependent	ADJ
fnp-2819	442	12	fashion	fashion	NOUN
fnp-2819	442	13	,	,	PUNCT
fnp-2819	442	14	but	but	CCONJ
fnp-2819	442	15	not	not	PART
fnp-2819	442	16	required	require	VERB
fnp-2819	442	17	for	for	ADP
fnp-2819	442	18	the	the	DET
fnp-2819	442	19	development	development	NOUN
fnp-2819	442	20	of	of	ADP
fnp-2819	442	21	autoimmune	autoimmune	ADJ
fnp-2819	442	22	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	442	23	.	.	PUNCT
fnp-2819	443	1	j.	j.	PROPN
fnp-2819	443	2	immunol	immunol	PROPN
fnp-2819	443	3	.	.	PUNCT
fnp-2819	444	1	179	179	NUM
fnp-2819	444	2	,	,	PUNCT
fnp-2819	444	3	8098	8098	NUM
fnp-2819	444	4	-	-	SYM
fnp-2819	444	5	8104	8104	NUM
fnp-2819	444	6	.	.	PUNCT
fnp-2819	445	1	https://doi.org.10.4049	https://doi.org.10.4049	PROPN
fnp-2819	445	2	/	/	SYM
fnp-2819	445	3	jimmunol.179.12.8098	jimmunol.179.12.8098	NOUN
fnp-2819	445	4	.	.	PUNCT
fnp-2819	446	1	lassmann	lassmann	PROPN
fnp-2819	446	2	,	,	PUNCT
fnp-2819	446	3	h.	h.	PROPN
fnp-2819	446	4	,	,	PUNCT
fnp-2819	446	5	2017	2017	NUM
fnp-2819	446	6	.	.	PUNCT
fnp-2819	447	1	targets	target	NOUN
fnp-2819	447	2	of	of	ADP
fnp-2819	447	3	therapy	therapy	NOUN
fnp-2819	447	4	in	in	ADP
fnp-2819	447	5	progressive	progressive	ADJ
fnp-2819	447	6	ms	ms	PROPN
fnp-2819	447	7	.	.	PROPN
fnp-2819	447	8	mult	mult	PROPN
fnp-2819	447	9	.	.	PROPN
fnp-2819	447	10	scler	scler	PROPN
fnp-2819	447	11	.	.	PUNCT
fnp-2819	448	1	23	23	NUM
fnp-2819	448	2	,	,	PUNCT
fnp-2819	448	3	1593	1593	NUM
fnp-2819	448	4	-	-	SYM
fnp-2819	448	5	1599	1599	NUM
fnp-2819	448	6	.	.	PUNCT
fnp-2819	449	1	https://doi.org/10.1177/1352458517729455	https://doi.org/10.1177/1352458517729455	X
fnp-2819	449	2	.	.	PUNCT
fnp-2819	450	1	lassmann	lassmann	PROPN
fnp-2819	450	2	,	,	PUNCT
fnp-2819	450	3	h.	h.	PROPN
fnp-2819	450	4	,	,	PUNCT
fnp-2819	450	5	bradl	bradl	NOUN
fnp-2819	450	6	,	,	PUNCT
fnp-2819	450	7	m.	m.	NOUN
fnp-2819	450	8	,	,	PUNCT
fnp-2819	450	9	2017	2017	NUM
fnp-2819	450	10	.	.	PUNCT
fnp-2819	451	1	multiple	multiple	ADJ
fnp-2819	451	2	sclerosis	sclerosis	NOUN
fnp-2819	451	3	:	:	PUNCT
fnp-2819	451	4	experimental	experimental	ADJ
fnp-2819	451	5	models	model	NOUN
fnp-2819	451	6	and	and	CCONJ
fnp-2819	451	7	reality	reality	NOUN
fnp-2819	451	8	.	.	PUNCT
fnp-2819	452	1	acta	acta	PROPN
fnp-2819	452	2	neuropathol	neuropathol	PROPN
fnp-2819	452	3	.	.	PUNCT
fnp-2819	453	1	133	133	NUM
fnp-2819	453	2	,	,	PUNCT
fnp-2819	453	3	223	223	NUM
fnp-2819	453	4	-	-	SYM
fnp-2819	453	5	244	244	NUM
fnp-2819	453	6	.	.	PUNCT
fnp-2819	454	1	https://doi.org/10.1007/s00401-016-1631-4	https://doi.org/10.1007/s00401-016-1631-4	NOUN
fnp-2819	454	2	.	.	PUNCT
fnp-2819	455	1	lalor	lalor	NOUN
fnp-2819	455	2	,	,	PUNCT
fnp-2819	455	3	s.j	s.j	PROPN
fnp-2819	455	4	.	.	PROPN
fnp-2819	455	5	,	,	PUNCT
fnp-2819	455	6	dungan	dungan	NUM
fnp-2819	455	7	,	,	PUNCT
fnp-2819	455	8	l.s	l.s	PROPN
fnp-2819	455	9	.	.	PROPN
fnp-2819	455	10	,	,	PUNCT
fnp-2819	455	11	sutton	sutton	PROPN
fnp-2819	455	12	,	,	PUNCT
fnp-2819	455	13	c.e	c.e	PROPN
fnp-2819	455	14	.	.	PROPN
fnp-2819	455	15	,	,	PUNCT
fnp-2819	455	16	basdeo	basdeo	PROPN
fnp-2819	455	17	,	,	PUNCT
fnp-2819	455	18	s.a	s.a	PROPN
fnp-2819	455	19	.	.	PROPN
fnp-2819	455	20	,	,	PUNCT
fnp-2819	455	21	fletcher	fletcher	PROPN
fnp-2819	455	22	,	,	PUNCT
fnp-2819	455	23	j.m	j.m	PROPN
fnp-2819	455	24	.	.	PROPN
fnp-2819	455	25	,	,	PUNCT
fnp-2819	455	26	mills	mill	NOUN
fnp-2819	455	27	,	,	PUNCT
fnp-2819	455	28	k.h	k.h	PROPN
fnp-2819	455	29	.	.	PROPN
fnp-2819	455	30	,	,	PUNCT
fnp-2819	455	31	2011	2011	NUM
fnp-2819	455	32	.	.	PUNCT
fnp-2819	456	1	caspase-1	caspase-1	NOUN
fnp-2819	456	2	-	-	PUNCT
fnp-2819	456	3	processed	process	VERB
fnp-2819	456	4	cytokines	cytokine	NOUN
fnp-2819	456	5	il-1beta	il-1beta	ADJ
fnp-2819	456	6	and	and	CCONJ
fnp-2819	456	7	il-18	il-18	ADP
fnp-2819	456	8	promote	promote	VERB
fnp-2819	456	9	il-17	il-17	ADP
fnp-2819	456	10	production	production	NOUN
fnp-2819	456	11	by	by	ADP
fnp-2819	456	12	gammadelta	gammadelta	NOUN
fnp-2819	456	13	and	and	CCONJ
fnp-2819	456	14	cd4	cd4	PROPN
fnp-2819	456	15	t	t	PROPN
fnp-2819	456	16	cells	cell	NOUN
fnp-2819	456	17	that	that	PRON
fnp-2819	456	18	mediate	mediate	VERB
fnp-2819	456	19	autoimmunity	autoimmunity	NOUN
fnp-2819	456	20	.	.	PUNCT
fnp-2819	457	1	j.	j.	PROPN
fnp-2819	457	2	immunol	immunol	PROPN
fnp-2819	457	3	.	.	PUNCT
fnp-2819	458	1	186	186	NUM
fnp-2819	458	2	,	,	PUNCT
fnp-2819	458	3	5738	5738	NUM
fnp-2819	458	4	-	-	SYM
fnp-2819	458	5	5748	5748	NUM
fnp-2819	458	6	.	.	PUNCT
fnp-2819	459	1	https://doi.org.10.4049	https://doi.org.10.4049	PROPN
fnp-2819	459	2	/	/	SYM
fnp-2819	459	3	jimmunol.1003597	jimmunol.1003597	PROPN
fnp-2819	459	4	.	.	PUNCT
fnp-2819	459	5	li	li	PROPN
fnp-2819	459	6	,	,	PUNCT
fnp-2819	459	7	j.	j.	PROPN
fnp-2819	459	8	,	,	PUNCT
fnp-2819	459	9	gran	gran	PROPN
fnp-2819	459	10	,	,	PUNCT
fnp-2819	459	11	b.	b.	PROPN
fnp-2819	459	12	,	,	PUNCT
fnp-2819	459	13	zhang	zhang	PROPN
fnp-2819	459	14	,	,	PUNCT
fnp-2819	459	15	g.x	g.x	PROPN
fnp-2819	459	16	.	.	PROPN
fnp-2819	459	17	,	,	PUNCT
fnp-2819	459	18	rostami	rostami	PROPN
fnp-2819	459	19	,	,	PUNCT
fnp-2819	459	20	a.	a.	NOUN
fnp-2819	459	21	,	,	PUNCT
fnp-2819	459	22	kamoun	kamoun	NOUN
fnp-2819	459	23	,	,	PUNCT
fnp-2819	459	24	m.	m.	NOUN
fnp-2819	459	25	,	,	PUNCT
fnp-2819	459	26	2005	2005	NUM
fnp-2819	459	27	.	.	PUNCT
fnp-2819	460	1	il-27	il-27	PROPN
fnp-2819	460	2	subunits	subunit	NOUN
fnp-2819	460	3	and	and	CCONJ
fnp-2819	460	4	its	its	PRON
fnp-2819	460	5	receptor	receptor	NOUN
fnp-2819	460	6	(	(	PUNCT
fnp-2819	460	7	wsx-1	wsx-1	NOUN
fnp-2819	460	8	)	)	PUNCT
fnp-2819	460	9	mrnas	mrna	NOUN
fnp-2819	460	10	are	be	AUX
fnp-2819	460	11	markedly	markedly	ADV
fnp-2819	460	12	up	up	ADV
fnp-2819	460	13	-	-	PUNCT
fnp-2819	460	14	regulated	regulate	VERB
fnp-2819	460	15	in	in	ADP
fnp-2819	460	16	inflammatory	inflammatory	ADJ
fnp-2819	460	17	cells	cell	NOUN
fnp-2819	460	18	in	in	ADP
fnp-2819	460	19	the	the	DET
fnp-2819	460	20	cns	cns	NOUN
fnp-2819	460	21	during	during	ADP
fnp-2819	460	22	experimental	experimental	ADJ
fnp-2819	460	23	autoimmune	autoimmune	ADJ
fnp-2819	460	24	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	460	25	.	.	PUNCT
fnp-2819	461	1	j.	j.	PROPN
fnp-2819	461	2	neurol	neurol	PROPN
fnp-2819	461	3	.	.	PUNCT
fnp-2819	462	1	sci	sci	PROPN
fnp-2819	462	2	.	.	PROPN
fnp-2819	462	3	232	232	NUM
fnp-2819	462	4	,	,	PUNCT
fnp-2819	462	5	3	3	NUM
fnp-2819	462	6	-	-	SYM
fnp-2819	462	7	9	9	NUM
fnp-2819	462	8	.	.	PUNCT
fnp-2819	463	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	463	2	/	/	SYM
fnp-2819	463	3	j.jns.2004.12.013	j.jns.2004.12.013	PROPN
fnp-2819	463	4	.	.	PUNCT
fnp-2819	464	1	lin	lin	PROPN
fnp-2819	464	2	,	,	PUNCT
fnp-2819	464	3	c.c	c.c	PROPN
fnp-2819	464	4	.	.	PROPN
fnp-2819	464	5	,	,	PUNCT
fnp-2819	464	6	bradstreet	bradstreet	PROPN
fnp-2819	464	7	,	,	PUNCT
fnp-2819	464	8	t.r	t.r	PROPN
fnp-2819	464	9	.	.	PROPN
fnp-2819	464	10	,	,	PUNCT
fnp-2819	464	11	schwarzkopf	schwarzkopf	PROPN
fnp-2819	464	12	,	,	PUNCT
fnp-2819	464	13	e.a	e.a	PROPN
fnp-2819	464	14	.	.	PROPN
fnp-2819	464	15	,	,	PUNCT
fnp-2819	464	16	jarjour	jarjour	PROPN
fnp-2819	464	17	,	,	PUNCT
fnp-2819	464	18	n.n	n.n	PROPN
fnp-2819	464	19	.	.	PROPN
fnp-2819	464	20	,	,	PUNCT
fnp-2819	464	21	chou	chou	PROPN
fnp-2819	464	22	,	,	PUNCT
fnp-2819	464	23	c.	c.	PROPN
fnp-2819	464	24	,	,	PUNCT
fnp-2819	464	25	archambault	archambault	PROPN
fnp-2819	464	26	,	,	PUNCT
fnp-2819	464	27	a.s	a.s	PROPN
fnp-2819	464	28	.	.	PROPN
fnp-2819	464	29	,	,	PUNCT
fnp-2819	464	30	sim	sim	PROPN
fnp-2819	464	31	,	,	PUNCT
fnp-2819	464	32	j.	j.	PROPN
fnp-2819	464	33	,	,	PUNCT
fnp-2819	464	34	zinselmeyer	zinselmeyer	PROPN
fnp-2819	464	35	,	,	PUNCT
fnp-2819	464	36	b.h	b.h	PROPN
fnp-2819	464	37	.	.	PROPN
fnp-2819	464	38	,	,	PUNCT
fnp-2819	464	39	carrero	carrero	PROPN
fnp-2819	464	40	,	,	PUNCT
fnp-2819	464	41	j.a	j.a	PROPN
fnp-2819	464	42	.	.	PROPN
fnp-2819	464	43	,	,	PUNCT
fnp-2819	464	44	wu	wu	PROPN
fnp-2819	464	45	,	,	PUNCT
fnp-2819	464	46	g.f	g.f	PROPN
fnp-2819	464	47	.	.	PROPN
fnp-2819	464	48	,	,	PUNCT
fnp-2819	464	49	taneja	taneja	PROPN
fnp-2819	464	50	,	,	PUNCT
fnp-2819	464	51	r.	r.	PROPN
fnp-2819	464	52	,	,	PUNCT
fnp-2819	464	53	artyomov	artyomov	PROPN
fnp-2819	464	54	,	,	PUNCT
fnp-2819	464	55	m.n	m.n	PROPN
fnp-2819	464	56	.	.	PROPN
fnp-2819	464	57	,	,	PUNCT
fnp-2819	464	58	russell	russell	PROPN
fnp-2819	464	59	,	,	PUNCT
fnp-2819	464	60	j.h	j.h	PROPN
fnp-2819	464	61	.	.	PROPN
fnp-2819	464	62	,	,	PUNCT
fnp-2819	464	63	edelson	edelson	PROPN
fnp-2819	464	64	,	,	PUNCT
fnp-2819	464	65	b.t	b.t	PROPN
fnp-2819	464	66	.	.	PROPN
fnp-2819	464	67	,	,	PUNCT
fnp-2819	464	68	2016	2016	NUM
fnp-2819	464	69	.	.	PUNCT
fnp-2819	465	1	il-1	il-1	ADV
fnp-2819	465	2	-	-	PUNCT
fnp-2819	465	3	induced	induce	VERB
fnp-2819	465	4	bhlhe40	bhlhe40	ADV
fnp-2819	465	5	identifies	identify	VERB
fnp-2819	465	6	pathogenic	pathogenic	ADJ
fnp-2819	465	7	t	t	PROPN
fnp-2819	465	8	helper	helper	NOUN
fnp-2819	465	9	cells	cell	NOUN
fnp-2819	465	10	in	in	ADP
fnp-2819	465	11	a	a	DET
fnp-2819	465	12	model	model	NOUN
fnp-2819	465	13	of	of	ADP
fnp-2819	465	14	autoimmune	autoimmune	ADJ
fnp-2819	465	15	neuroinflammation	neuroinflammation	PROPN
fnp-2819	465	16	.	.	PUNCT
fnp-2819	466	1	j.	j.	PROPN
fnp-2819	466	2	exp	exp	PROPN
fnp-2819	466	3	.	.	PROPN
fnp-2819	466	4	med	med	PROPN
fnp-2819	466	5	.	.	PROPN
fnp-2819	466	6	213	213	NUM
fnp-2819	466	7	,	,	PUNCT
fnp-2819	466	8	251	251	NUM
fnp-2819	466	9	-	-	SYM
fnp-2819	466	10	271	271	NUM
fnp-2819	466	11	.	.	PUNCT
fnp-2819	467	1	https://doi.org.10.1084	https://doi.org.10.1084	NOUN
fnp-2819	467	2	/	/	SYM
fnp-2819	467	3	jem.20150568	jem.20150568	PROPN
fnp-2819	467	4	.	.	PUNCT
fnp-2819	468	1	liu	liu	PROPN
fnp-2819	468	2	,	,	PUNCT
fnp-2819	468	3	z.	z.	PROPN
fnp-2819	468	4	,	,	PUNCT
fnp-2819	468	5	zhang	zhang	PROPN
fnp-2819	468	6	,	,	PUNCT
fnp-2819	468	7	c.	c.	PROPN
fnp-2819	468	8	,	,	PUNCT
fnp-2819	468	9	sun	sun	PROPN
fnp-2819	468	10	,	,	PUNCT
fnp-2819	468	11	j.	j.	PROPN
fnp-2819	468	12	,	,	PUNCT
fnp-2819	468	13	2010	2010	NUM
fnp-2819	468	14	.	.	PUNCT
fnp-2819	468	15	deacetylase	deacetylase	VERB
fnp-2819	468	16	inhibitor	inhibitor	NOUN
fnp-2819	468	17	trichostatin	trichostatin	NOUN
fnp-2819	468	18	a	a	DET
fnp-2819	468	19	down	down	NOUN
fnp-2819	468	20	-	-	PUNCT
fnp-2819	468	21	regulates	regulate	VERB
fnp-2819	468	22	foxp3	foxp3	NOUN
fnp-2819	468	23	expression	expression	NOUN
fnp-2819	468	24	and	and	CCONJ
fnp-2819	468	25	reduces	reduce	VERB
fnp-2819	468	26	cd4+cd25	cd4+cd25	PROPN
fnp-2819	468	27	+	+	NOUN
fnp-2819	468	28	regulatory	regulatory	ADJ
fnp-2819	468	29	t	t	NOUN
fnp-2819	468	30	cells	cell	NOUN
fnp-2819	468	31	.	.	PUNCT
fnp-2819	469	1	biochem	biochem	PROPN
fnp-2819	469	2	.	.	PUNCT
fnp-2819	470	1	biophys	biophy	NOUN
fnp-2819	470	2	.	.	PUNCT
fnp-2819	471	1	res	re	NOUN
fnp-2819	471	2	.	.	PUNCT
fnp-2819	472	1	commun	commun	PROPN
fnp-2819	472	2	.	.	PUNCT
fnp-2819	473	1	400	400	NUM
fnp-2819	473	2	,	,	PUNCT
fnp-2819	473	3	409	409	NUM
fnp-2819	473	4	-	-	SYM
fnp-2819	473	5	412	412	NUM
fnp-2819	473	6	.	.	PUNCT
fnp-2819	474	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	474	2	/	/	SYM
fnp-2819	474	3	j.bbrc.2010.08.090	j.bbrc.2010.08.090	PROPN
fnp-2819	474	4	.	.	PROPN
fnp-2819	475	1	mahad	mahad	PROPN
fnp-2819	475	2	,	,	PUNCT
fnp-2819	475	3	d.j	d.j	PROPN
fnp-2819	475	4	.	.	PROPN
fnp-2819	475	5	,	,	PUNCT
fnp-2819	475	6	ransohoff	ransohoff	PROPN
fnp-2819	475	7	,	,	PUNCT
fnp-2819	475	8	r.m	r.m	PROPN
fnp-2819	475	9	.	.	PROPN
fnp-2819	475	10	,	,	PUNCT
fnp-2819	475	11	2003	2003	NUM
fnp-2819	475	12	.	.	PUNCT
fnp-2819	476	1	the	the	DET
fnp-2819	476	2	role	role	NOUN
fnp-2819	476	3	of	of	ADP
fnp-2819	476	4	mcp-1	mcp-1	X
fnp-2819	476	5	(	(	PUNCT
fnp-2819	476	6	ccl2	ccl2	PROPN
fnp-2819	476	7	)	)	PUNCT
fnp-2819	476	8	and	and	CCONJ
fnp-2819	476	9	ccr2	ccr2	NOUN
fnp-2819	476	10	in	in	ADP
fnp-2819	476	11	multiple	multiple	ADJ
fnp-2819	476	12	sclerosis	sclerosis	NOUN
fnp-2819	476	13	and	and	CCONJ
fnp-2819	476	14	experimental	experimental	ADJ
fnp-2819	476	15	autoimmune	autoimmune	ADJ
fnp-2819	476	16	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	476	17	(	(	PUNCT
fnp-2819	476	18	eae	eae	PROPN
fnp-2819	476	19	)	)	PUNCT
fnp-2819	476	20	.	.	PUNCT
fnp-2819	477	1	semin	semin	PROPN
fnp-2819	477	2	.	.	PUNCT
fnp-2819	478	1	immunol	immunol	PROPN
fnp-2819	478	2	.	.	PUNCT
fnp-2819	479	1	15	15	NUM
fnp-2819	479	2	,	,	PUNCT
fnp-2819	479	3	23	23	NUM
fnp-2819	479	4	-	-	SYM
fnp-2819	479	5	32	32	NUM
fnp-2819	479	6	.	.	PUNCT
fnp-2819	480	1	pmid:12495638	pmid:12495638	NOUN
fnp-2819	480	2	.	.	PUNCT
fnp-2819	481	1	martinez	martinez	PROPN
fnp-2819	481	2	,	,	PUNCT
fnp-2819	481	3	n.e	n.e	PROPN
fnp-2819	481	4	.	.	PROPN
fnp-2819	481	5	,	,	PUNCT
fnp-2819	481	6	sato	sato	PROPN
fnp-2819	481	7	,	,	PUNCT
fnp-2819	481	8	f.	f.	PROPN
fnp-2819	481	9	,	,	PUNCT
fnp-2819	481	10	omura	omura	PROPN
fnp-2819	481	11	,	,	PUNCT
fnp-2819	481	12	s.	s.	PROPN
fnp-2819	481	13	,	,	PUNCT
fnp-2819	481	14	kawai	kawai	PROPN
fnp-2819	481	15	,	,	PUNCT
fnp-2819	481	16	e.	e.	PROPN
fnp-2819	481	17	,	,	PUNCT
fnp-2819	481	18	takahashi	takahashi	PROPN
fnp-2819	481	19	,	,	PUNCT
fnp-2819	481	20	s.	s.	PROPN
fnp-2819	481	21	,	,	PUNCT
fnp-2819	481	22	yoh	yoh	PROPN
fnp-2819	481	23	,	,	PUNCT
fnp-2819	481	24	k.	k.	PROPN
fnp-2819	481	25	,	,	PUNCT
fnp-2819	481	26	tsunoda	tsunoda	PROPN
fnp-2819	481	27	,	,	PUNCT
fnp-2819	481	28	i.	i.	PROPN
fnp-2819	481	29	,	,	PUNCT
fnp-2819	481	30	2014	2014	NUM
fnp-2819	481	31	.	.	PUNCT
fnp-2819	482	1	rorγt	rorγt	NOUN
fnp-2819	482	2	,	,	PUNCT
fnp-2819	482	3	but	but	CCONJ
fnp-2819	482	4	not	not	PART
fnp-2819	482	5	t	t	NOUN
fnp-2819	482	6	-	-	PUNCT
fnp-2819	482	7	bet	bet	NOUN
fnp-2819	482	8	,	,	PUNCT
fnp-2819	482	9	overexpression	overexpression	NOUN
fnp-2819	482	10	exacerbates	exacerbate	VERB
fnp-2819	482	11	an	an	DET
fnp-2819	482	12	autoimmune	autoimmune	ADJ
fnp-2819	482	13	model	model	NOUN
fnp-2819	482	14	for	for	ADP
fnp-2819	482	15	multiple	multiple	ADJ
fnp-2819	482	16	sclerosis	sclerosis	NOUN
fnp-2819	482	17	.	.	PUNCT
fnp-2819	483	1	j.	j.	PROPN
fnp-2819	483	2	neuroimmunol	neuroimmunol	PROPN
fnp-2819	483	3	.	.	PUNCT
fnp-2819	484	1	276	276	NUM
fnp-2819	484	2	,	,	PUNCT
fnp-2819	484	3	142	142	NUM
fnp-2819	484	4	-	-	SYM
fnp-2819	484	5	149	149	NUM
fnp-2819	484	6	.	.	PUNCT
fnp-2819	485	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	485	2	/	/	SYM
fnp-2819	485	3	j.jneuroim.2014.09.006	j.jneuroim.2014.09.006	PROPN
fnp-2819	485	4	.	.	PUNCT
fnp-2819	485	5	mascanfroni	mascanfroni	PROPN
fnp-2819	485	6	,	,	PUNCT
fnp-2819	485	7	i.d	i.d	PROPN
fnp-2819	485	8	.	.	PROPN
fnp-2819	485	9	,	,	PUNCT
fnp-2819	485	10	yeste	yeste	NOUN
fnp-2819	485	11	,	,	PUNCT
fnp-2819	485	12	a.	a.	NOUN
fnp-2819	485	13	,	,	PUNCT
fnp-2819	485	14	vieira	vieira	PROPN
fnp-2819	485	15	,	,	PUNCT
fnp-2819	485	16	s.m	s.m	PROPN
fnp-2819	485	17	.	.	PROPN
fnp-2819	485	18	,	,	PUNCT
fnp-2819	485	19	burns	burn	NOUN
fnp-2819	485	20	,	,	PUNCT
fnp-2819	485	21	e.j	e.j	PROPN
fnp-2819	485	22	.	.	PROPN
fnp-2819	485	23	,	,	PUNCT
fnp-2819	485	24	patel	patel	PROPN
fnp-2819	485	25	,	,	PUNCT
fnp-2819	485	26	b.	b.	PROPN
fnp-2819	485	27	,	,	PUNCT
fnp-2819	485	28	sloma	sloma	NOUN
fnp-2819	485	29	,	,	PUNCT
fnp-2819	485	30	i.	i.	PROPN
fnp-2819	485	31	,	,	PUNCT
fnp-2819	485	32	wu	wu	PROPN
fnp-2819	485	33	,	,	PUNCT
fnp-2819	485	34	y.	y.	PROPN
fnp-2819	485	35	,	,	PUNCT
fnp-2819	485	36	mayo	mayo	NOUN
fnp-2819	485	37	,	,	PUNCT
fnp-2819	485	38	l.	l.	PROPN
fnp-2819	485	39	,	,	PUNCT
fnp-2819	485	40	ben	ben	PROPN
fnp-2819	485	41	-	-	PUNCT
fnp-2819	485	42	hamo	hamo	PROPN
fnp-2819	485	43	,	,	PUNCT
fnp-2819	485	44	r.	r.	PROPN
fnp-2819	485	45	,	,	PUNCT
fnp-2819	485	46	efroni	efroni	ADJ
fnp-2819	485	47	,	,	PUNCT
fnp-2819	485	48	s.	s.	PROPN
fnp-2819	485	49	,	,	PUNCT
fnp-2819	485	50	kuchroo	kuchroo	PROPN
fnp-2819	485	51	,	,	PUNCT
fnp-2819	485	52	v.k	v.k	PROPN
fnp-2819	485	53	.	.	PROPN
fnp-2819	485	54	,	,	PUNCT
fnp-2819	485	55	robson	robson	PROPN
fnp-2819	485	56	,	,	PUNCT
fnp-2819	485	57	s.c	s.c	PROPN
fnp-2819	485	58	.	.	PROPN
fnp-2819	485	59	,	,	PUNCT
fnp-2819	485	60	quintana	quintana	PROPN
fnp-2819	485	61	,	,	PUNCT
fnp-2819	485	62	f.j	f.j	PROPN
fnp-2819	485	63	.	.	PROPN
fnp-2819	485	64	,	,	PUNCT
fnp-2819	485	65	2013	2013	NUM
fnp-2819	485	66	.	.	PUNCT
fnp-2819	486	1	il-27	il-27	PROPN
fnp-2819	486	2	acts	act	VERB
fnp-2819	486	3	on	on	ADP
fnp-2819	486	4	dcs	dcs	PROPN
fnp-2819	486	5	to	to	PART
fnp-2819	486	6	suppress	suppress	VERB
fnp-2819	486	7	the	the	DET
fnp-2819	486	8	t	t	NOUN
fnp-2819	486	9	cell	cell	NOUN
fnp-2819	486	10	response	response	NOUN
fnp-2819	486	11	and	and	CCONJ
fnp-2819	486	12	autoimmunity	autoimmunity	NOUN
fnp-2819	486	13	by	by	ADP
fnp-2819	486	14	inducing	induce	VERB
fnp-2819	486	15	expression	expression	NOUN
fnp-2819	486	16	of	of	ADP
fnp-2819	486	17	the	the	DET
fnp-2819	486	18	immunoregulatory	immunoregulatory	ADJ
fnp-2819	486	19	molecule	molecule	NOUN
fnp-2819	486	20	cd39	cd39	PROPN
fnp-2819	486	21	.	.	PUNCT
fnp-2819	487	1	nat	nat	PROPN
fnp-2819	487	2	.	.	PUNCT
fnp-2819	488	1	immunol	immunol	PROPN
fnp-2819	488	2	.	.	PUNCT
fnp-2819	489	1	14,1054	14,1054	PROPN
fnp-2819	489	2	-	-	PUNCT
fnp-2819	489	3	1063	1063	NUM
fnp-2819	489	4	.	.	PUNCT
fnp-2819	490	1	https://doi.org.10.1038	https://doi.org.10.1038	PROPN
fnp-2819	490	2	/	/	SYM
fnp-2819	490	3	ni.2695	ni.2695	PROPN
fnp-2819	490	4	.	.	PUNCT
fnp-2819	490	5	mcqualter	mcqualter	PROPN
fnp-2819	490	6	,	,	PUNCT
fnp-2819	490	7	j.l	j.l	PROPN
fnp-2819	490	8	.	.	PROPN
fnp-2819	490	9	,	,	PUNCT
fnp-2819	490	10	darwiche	darwiche	PROPN
fnp-2819	490	11	,	,	PUNCT
fnp-2819	490	12	r.	r.	PROPN
fnp-2819	490	13	,	,	PUNCT
fnp-2819	490	14	ewing	ewing	PROPN
fnp-2819	490	15	,	,	PUNCT
fnp-2819	490	16	c.	c.	PROPN
fnp-2819	490	17	,	,	PUNCT
fnp-2819	490	18	onuki	onuki	PROPN
fnp-2819	490	19	,	,	PUNCT
fnp-2819	490	20	m.	m.	NOUN
fnp-2819	490	21	,	,	PUNCT
fnp-2819	490	22	kay	kay	PROPN
fnp-2819	490	23	,	,	PUNCT
fnp-2819	490	24	t.w	t.w	PROPN
fnp-2819	490	25	.	.	PROPN
fnp-2819	490	26	,	,	PUNCT
fnp-2819	490	27	hamilton	hamilton	PROPN
fnp-2819	490	28	,	,	PUNCT
fnp-2819	490	29	j.a	j.a	PROPN
fnp-2819	490	30	,	,	PUNCT
fnp-2819	490	31	reid	reid	PROPN
fnp-2819	490	32	,	,	PUNCT
fnp-2819	490	33	h.h	h.h	PROPN
fnp-2819	490	34	.	.	PROPN
fnp-2819	490	35	,	,	PUNCT
fnp-2819	490	36	bernard	bernard	PROPN
fnp-2819	490	37	,	,	PUNCT
fnp-2819	490	38	c.c	c.c	PROPN
fnp-2819	490	39	.	.	PROPN
fnp-2819	490	40	,	,	PUNCT
fnp-2819	490	41	2001	2001	NUM
fnp-2819	490	42	.	.	PUNCT
fnp-2819	491	1	granulocyte	granulocyte	ADJ
fnp-2819	491	2	macrophage	macrophage	ADJ
fnp-2819	491	3	colony	colony	NOUN
fnp-2819	491	4	-	-	PUNCT
fnp-2819	491	5	stimulating	stimulate	VERB
fnp-2819	491	6	factor	factor	NOUN
fnp-2819	491	7	:	:	PUNCT
fnp-2819	491	8	a	a	DET
fnp-2819	491	9	new	new	ADJ
fnp-2819	491	10	putative	putative	ADJ
fnp-2819	491	11	therapeutic	therapeutic	ADJ
fnp-2819	491	12	target	target	NOUN
fnp-2819	491	13	in	in	ADP
fnp-2819	491	14	multiple	multiple	ADJ
fnp-2819	491	15	sclerosis	sclerosis	NOUN
fnp-2819	491	16	.	.	PUNCT
fnp-2819	492	1	j.	j.	PROPN
fnp-2819	492	2	exp	exp	PROPN
fnp-2819	492	3	.	.	PROPN
fnp-2819	492	4	med	med	PROPN
fnp-2819	492	5	.	.	PROPN
fnp-2819	492	6	194	194	NUM
fnp-2819	492	7	,	,	PUNCT
fnp-2819	492	8	873	873	NUM
fnp-2819	492	9	-	-	SYM
fnp-2819	492	10	882	882	NUM
fnp-2819	492	11	.	.	PUNCT
fnp-2819	493	1	https://doi.org:10.1084	https://doi.org:10.1084	PROPN
fnp-2819	493	2	/	/	SYM
fnp-2819	493	3	jem.194.7.873	jem.194.7.873	PROPN
fnp-2819	493	4	.	.	PUNCT
fnp-2819	494	1	moreira	moreira	PROPN
fnp-2819	494	2	,	,	PUNCT
fnp-2819	494	3	m.a	m.a	PROPN
fnp-2819	494	4	.	.	PROPN
fnp-2819	494	5	,	,	PUNCT
fnp-2819	494	6	tilbery	tilbery	NOUN
fnp-2819	494	7	,	,	PUNCT
fnp-2819	494	8	c.p	c.p	PROPN
fnp-2819	494	9	.	.	PROPN
fnp-2819	494	10	,	,	PUNCT
fnp-2819	494	11	monteiro	monteiro	PROPN
fnp-2819	494	12	,	,	PUNCT
fnp-2819	494	13	l.p	l.p	PROPN
fnp-2819	494	14	.	.	PROPN
fnp-2819	494	15	,	,	PUNCT
fnp-2819	494	16	teixeira	teixeira	PROPN
fnp-2819	494	17	,	,	PUNCT
fnp-2819	494	18	m.m	m.m	PROPN
fnp-2819	494	19	.	.	PROPN
fnp-2819	494	20	,	,	PUNCT
fnp-2819	494	21	teixeira	teixeira	PROPN
fnp-2819	494	22	,	,	PUNCT
fnp-2819	494	23	a.l	a.l	PROPN
fnp-2819	494	24	.	.	PROPN
fnp-2819	494	25	,	,	PUNCT
fnp-2819	494	26	2006	2006	NUM
fnp-2819	494	27	.	.	PUNCT
fnp-2819	495	1	effect	effect	NOUN
fnp-2819	495	2	of	of	ADP
fnp-2819	495	3	the	the	DET
fnp-2819	495	4	treatment	treatment	NOUN
fnp-2819	495	5	with	with	ADP
fnp-2819	495	6	methylprednisolone	methylprednisolone	NOUN
fnp-2819	495	7	on	on	ADP
fnp-2819	495	8	the	the	DET
fnp-2819	495	9	cerebrospinal	cerebrospinal	ADJ
fnp-2819	495	10	fluid	fluid	NOUN
fnp-2819	495	11	and	and	CCONJ
fnp-2819	495	12	serum	serum	NOUN
fnp-2819	495	13	levels	level	NOUN
fnp-2819	495	14	of	of	ADP
fnp-2819	495	15	ccl2	ccl2	NOUN
fnp-2819	495	16	and	and	CCONJ
fnp-2819	495	17	cxcl10	cxcl10	VERB
fnp-2819	495	18	chemokines	chemokine	NOUN
fnp-2819	495	19	in	in	ADP
fnp-2819	495	20	patients	patient	NOUN
fnp-2819	495	21	with	with	ADP
fnp-2819	495	22	active	active	ADJ
fnp-2819	495	23	multiple	multiple	ADJ
fnp-2819	495	24	sclerosis	sclerosis	NOUN
fnp-2819	495	25	.	.	PUNCT
fnp-2819	496	1	acta	acta	PROPN
fnp-2819	496	2	neurol	neurol	PROPN
fnp-2819	496	3	.	.	PUNCT
fnp-2819	497	1	scand	scand	PROPN
fnp-2819	497	2	.	.	PROPN
fnp-2819	498	1	114	114	NUM
fnp-2819	498	2	,	,	PUNCT
fnp-2819	498	3	109	109	NUM
fnp-2819	498	4	-	-	SYM
fnp-2819	498	5	113	113	NUM
fnp-2819	498	6	.	.	PUNCT
fnp-2819	499	1	https://doi.org/10.1111/j.1600-0404.2006.00629	https://doi.org/10.1111/j.1600-0404.2006.00629	PROPN
fnp-2819	499	2	.	.	PUNCT
fnp-2819	500	1	moreno	moreno	PROPN
fnp-2819	500	2	,	,	PUNCT
fnp-2819	500	3	m.	m.	NOUN
fnp-2819	500	4	,	,	PUNCT
fnp-2819	500	5	bannerman	bannerman	PROPN
fnp-2819	500	6	,	,	PUNCT
fnp-2819	500	7	p.	p.	PROPN
fnp-2819	500	8	,	,	PUNCT
fnp-2819	500	9	ma	ma	PROPN
fnp-2819	500	10	,	,	PUNCT
fnp-2819	500	11	j.	j.	PROPN
fnp-2819	500	12	,	,	PUNCT
fnp-2819	500	13	guo	guo	PROPN
fnp-2819	500	14	,	,	PUNCT
fnp-2819	500	15	f.	f.	PROPN
fnp-2819	500	16	,	,	PUNCT
fnp-2819	500	17	miers	miers	PROPN
fnp-2819	500	18	,	,	PUNCT
fnp-2819	500	19	l.	l.	PROPN
fnp-2819	500	20	,	,	PUNCT
fnp-2819	500	21	soulika	soulika	PROPN
fnp-2819	500	22	,	,	PUNCT
fnp-2819	500	23	a.m.	a.m.	ADV
fnp-2819	500	24	,	,	PUNCT
fnp-2819	500	25	pleasure	pleasure	NOUN
fnp-2819	500	26	,	,	PUNCT
fnp-2819	500	27	d.	d.	PROPN
fnp-2819	500	28	,	,	PUNCT
fnp-2819	500	29	2014	2014	NUM
fnp-2819	500	30	.	.	PUNCT
fnp-2819	501	1	conditional	conditional	ADJ
fnp-2819	501	2	ablation	ablation	NOUN
fnp-2819	501	3	of	of	ADP
fnp-2819	501	4	astroglial	astroglial	ADJ
fnp-2819	501	5	ccl2	ccl2	NOUN
fnp-2819	501	6	suppresses	suppress	VERB
fnp-2819	501	7	cns	cns	NOUN
fnp-2819	501	8	accumulation	accumulation	NOUN
fnp-2819	501	9	of	of	ADP
fnp-2819	501	10	m1	m1	PROPN
fnp-2819	501	11	macrophages	macrophage	NOUN
fnp-2819	501	12	and	and	CCONJ
fnp-2819	501	13	preserves	preserve	VERB
fnp-2819	501	14	axons	axon	NOUN
fnp-2819	501	15	in	in	ADP
fnp-2819	501	16	mice	mouse	NOUN
fnp-2819	501	17	with	with	ADP
fnp-2819	501	18	mog	mog	NOUN
fnp-2819	501	19	peptide	peptide	NOUN
fnp-2819	501	20	eae	eae	PROPN
fnp-2819	501	21	.	.	PUNCT
fnp-2819	502	1	j.	j.	PROPN
fnp-2819	502	2	neurosci	neurosci	PROPN
fnp-2819	502	3	.	.	PUNCT
fnp-2819	503	1	34	34	NUM
fnp-2819	503	2	,	,	PUNCT
fnp-2819	503	3	8175	8175	NUM
fnp-2819	503	4	-	-	SYM
fnp-2819	503	5	8185	8185	NUM
fnp-2819	503	6	.	.	PUNCT
fnp-2819	504	1	https://doi.org.10.1523	https://doi.org.10.1523	NOUN
fnp-2819	504	2	/	/	SYM
fnp-2819	504	3	jneurosci.1137	jneurosci.1137	NOUN
fnp-2819	504	4	-	-	PUNCT
fnp-2819	504	5	14.2014	14.2014	NUM
fnp-2819	504	6	.	.	PUNCT
fnp-2819	505	1	nakahama	nakahama	PROPN
fnp-2819	505	2	,	,	PUNCT
fnp-2819	505	3	t.	t.	PROPN
fnp-2819	505	4	,	,	PUNCT
fnp-2819	505	5	hanieh	hanieh	PROPN
fnp-2819	505	6	,	,	PUNCT
fnp-2819	505	7	h.	h.	PROPN
fnp-2819	505	8	,	,	PUNCT
fnp-2819	505	9	nguyen	nguyen	PROPN
fnp-2819	505	10	,	,	PUNCT
fnp-2819	505	11	n.t	n.t	PROPN
fnp-2819	505	12	.	.	PROPN
fnp-2819	505	13	,	,	PUNCT
fnp-2819	505	14	chinen	chinen	PROPN
fnp-2819	505	15	,	,	PUNCT
fnp-2819	505	16	i.	i.	PROPN
fnp-2819	505	17	,	,	PUNCT
fnp-2819	505	18	ripley	ripley	PROPN
fnp-2819	505	19	,	,	PUNCT
fnp-2819	505	20	b.	b.	PROPN
fnp-2819	505	21	,	,	PUNCT
fnp-2819	505	22	millrine	millrine	PROPN
fnp-2819	505	23	,	,	PUNCT
fnp-2819	505	24	d.	d.	PROPN
fnp-2819	505	25	,	,	PUNCT
fnp-2819	505	26	lee	lee	PROPN
fnp-2819	505	27	,	,	PUNCT
fnp-2819	505	28	s.	s.	PROPN
fnp-2819	505	29	,	,	PUNCT
fnp-2819	505	30	nyati	nyati	PROPN
fnp-2819	505	31	,	,	PUNCT
fnp-2819	505	32	k.k	k.k	PROPN
fnp-2819	505	33	.	.	PROPN
fnp-2819	505	34	,	,	PUNCT
fnp-2819	505	35	dubey	dubey	PROPN
fnp-2819	505	36	,	,	PUNCT
fnp-2819	505	37	p.k	p.k	PROPN
fnp-2819	505	38	.	.	PROPN
fnp-2819	505	39	,	,	PUNCT
fnp-2819	505	40	chowdhury	chowdhury	PROPN
fnp-2819	505	41	,	,	PUNCT
fnp-2819	505	42	k.	k.	PROPN
fnp-2819	505	43	,	,	PUNCT
fnp-2819	505	44	kawahara	kawahara	PROPN
fnp-2819	505	45	,	,	PUNCT
fnp-2819	505	46	y.	y.	PROPN
fnp-2819	505	47	,	,	PUNCT
fnp-2819	505	48	kishimoto	kishimoto	PROPN
fnp-2819	505	49	,	,	PUNCT
fnp-2819	505	50	t.	t.	PROPN
fnp-2819	505	51	,	,	PUNCT
fnp-2819	505	52	2013	2013	NUM
fnp-2819	505	53	.	.	PUNCT
fnp-2819	506	1	aryl	aryl	NOUN
fnp-2819	506	2	hydrocarbon	hydrocarbon	NOUN
fnp-2819	506	3	receptor	receptor	NOUN
fnp-2819	506	4	-	-	PUNCT
fnp-2819	506	5	mediated	mediate	VERB
fnp-2819	506	6	induction	induction	NOUN
fnp-2819	506	7	of	of	ADP
fnp-2819	506	8	the	the	DET
fnp-2819	506	9	microrna-132/212	microrna-132/212	ADJ
fnp-2819	506	10	cluster	cluster	NOUN
fnp-2819	506	11	promotes	promote	VERB
fnp-2819	506	12	interleukin-17	interleukin-17	ADV
fnp-2819	506	13	-	-	PUNCT
fnp-2819	506	14	producing	produce	VERB
fnp-2819	506	15	t	t	NOUN
fnp-2819	506	16	-	-	PUNCT
fnp-2819	506	17	helper	helper	NOUN
fnp-2819	506	18	cell	cell	NOUN
fnp-2819	506	19	differentiation	differentiation	NOUN
fnp-2819	506	20	.	.	PUNCT
fnp-2819	507	1	proc	proc	NOUN
fnp-2819	507	2	.	.	PUNCT
fnp-2819	508	1	natl	natl	PROPN
fnp-2819	508	2	.	.	PUNCT
fnp-2819	509	1	acad	acad	PROPN
fnp-2819	509	2	.	.	PUNCT
fnp-2819	510	1	sci	sci	PROPN
fnp-2819	510	2	.	.	PROPN
fnp-2819	510	3	usa	usa	PROPN
fnp-2819	510	4	110	110	NUM
fnp-2819	510	5	,	,	PUNCT
fnp-2819	510	6	11964	11964	NUM
fnp-2819	510	7	-	-	SYM
fnp-2819	510	8	11969	11969	NUM
fnp-2819	510	9	.	.	PUNCT
fnp-2819	511	1	https://doi.org.10.1073	https://doi.org.10.1073	NOUN
fnp-2819	511	2	/	/	SYM
fnp-2819	511	3	pnas.1311087110	pnas.1311087110	PROPN
fnp-2819	511	4	.	.	PUNCT
fnp-2819	511	5	narikawa	narikawa	PROPN
fnp-2819	511	6	,	,	PUNCT
fnp-2819	511	7	k.	k.	PROPN
fnp-2819	511	8	,	,	PUNCT
fnp-2819	511	9	misu	misu	PROPN
fnp-2819	511	10	,	,	PUNCT
fnp-2819	511	11	t.	t.	NOUN
fnp-2819	511	12	,	,	PUNCT
fnp-2819	511	13	fujihara	fujihara	PROPN
fnp-2819	511	14	,	,	PUNCT
fnp-2819	511	15	k.	k.	PROPN
fnp-2819	511	16	,	,	PUNCT
fnp-2819	511	17	nakashima	nakashima	PROPN
fnp-2819	511	18	,	,	PUNCT
fnp-2819	511	19	i.	i.	PROPN
fnp-2819	511	20	,	,	PUNCT
fnp-2819	511	21	sato	sato	PROPN
fnp-2819	511	22	,	,	PUNCT
fnp-2819	511	23	s.	s.	PROPN
fnp-2819	511	24	,	,	PUNCT
fnp-2819	511	25	itoyama	itoyama	NOUN
fnp-2819	511	26	,	,	PUNCT
fnp-2819	511	27	y.	y.	NOUN
fnp-2819	511	28	,	,	PUNCT
fnp-2819	511	29	2004	2004	NUM
fnp-2819	511	30	.	.	PUNCT
fnp-2819	512	1	csf	csf	ADJ
fnp-2819	512	2	chemokine	chemokine	ADJ
fnp-2819	512	3	levels	level	NOUN
fnp-2819	512	4	in	in	ADP
fnp-2819	512	5	relapsing	relapse	VERB
fnp-2819	512	6	neuromyelitis	neuromyelitis	PROPN
fnp-2819	512	7	optica	optica	NOUN
fnp-2819	512	8	and	and	CCONJ
fnp-2819	512	9	multiple	multiple	ADJ
fnp-2819	512	10	sclerosis	sclerosis	NOUN
fnp-2819	512	11	.	.	PUNCT
fnp-2819	513	1	j.	j.	PROPN
fnp-2819	513	2	neuroimmunol	neuroimmunol	PROPN
fnp-2819	513	3	.	.	PUNCT
fnp-2819	514	1	149	149	NUM
fnp-2819	514	2	,	,	PUNCT
fnp-2819	514	3	182	182	NUM
fnp-2819	514	4	-	-	SYM
fnp-2819	514	5	186	186	NUM
fnp-2819	514	6	.	.	PUNCT
fnp-2819	515	1	https://doi.org/	https://doi.org/	NOUN
fnp-2819	515	2	10.1016	10.1016	NUM
fnp-2819	515	3	/	/	SYM
fnp-2819	515	4	j.jneuroim.2003.12.010	j.jneuroim.2003.12.010	PROPN
fnp-2819	515	5	.	.	PUNCT
fnp-2819	516	1	niino	niino	PROPN
fnp-2819	516	2	,	,	PUNCT
fnp-2819	516	3	m.	m.	NOUN
fnp-2819	516	4	,	,	PUNCT
fnp-2819	516	5	ogata	ogata	PROPN
fnp-2819	516	6	,	,	PUNCT
fnp-2819	516	7	a.	a.	PROPN
fnp-2819	516	8	,	,	PUNCT
fnp-2819	516	9	kikuchi	kikuchi	PROPN
fnp-2819	516	10	,	,	PUNCT
fnp-2819	516	11	s.	s.	PROPN
fnp-2819	516	12	,	,	PUNCT
fnp-2819	516	13	tashiro	tashiro	PROPN
fnp-2819	516	14	,	,	PUNCT
fnp-2819	516	15	k.	k.	PROPN
fnp-2819	516	16	,	,	PUNCT
fnp-2819	516	17	nishihira	nishihira	PROPN
fnp-2819	516	18	,	,	PUNCT
fnp-2819	516	19	j.	j.	PROPN
fnp-2819	516	20	,	,	PUNCT
fnp-2819	516	21	2000	2000	NUM
fnp-2819	516	22	.	.	PUNCT
fnp-2819	517	1	macrophage	macrophage	ADJ
fnp-2819	517	2	migration	migration	NOUN
fnp-2819	517	3	inhibitory	inhibitory	ADJ
fnp-2819	517	4	factor	factor	NOUN
fnp-2819	517	5	in	in	ADP
fnp-2819	517	6	the	the	DET
fnp-2819	517	7	cerebrospinal	cerebrospinal	ADJ
fnp-2819	517	8	fluid	fluid	NOUN
fnp-2819	517	9	of	of	ADP
fnp-2819	517	10	patients	patient	NOUN
fnp-2819	517	11	with	with	ADP
fnp-2819	517	12	conventional	conventional	ADJ
fnp-2819	517	13	and	and	CCONJ
fnp-2819	517	14	optic	optic	ADJ
fnp-2819	517	15	-	-	PUNCT
fnp-2819	517	16	spinal	spinal	NOUN
fnp-2819	517	17	forms	form	NOUN
fnp-2819	517	18	of	of	ADP
fnp-2819	517	19	multiple	multiple	ADJ
fnp-2819	517	20	sclerosis	sclerosis	NOUN
fnp-2819	517	21	and	and	CCONJ
fnp-2819	517	22	neuro	neuro	PROPN
fnp-2819	517	23	-	-	PUNCT
fnp-2819	517	24	behçet	behçet	PROPN
fnp-2819	517	25	's	's	PART
fnp-2819	517	26	disease	disease	NOUN
fnp-2819	517	27	.	.	PUNCT
fnp-2819	518	1	j.	j.	PROPN
fnp-2819	518	2	neurol	neurol	PROPN
fnp-2819	518	3	.	.	PUNCT
fnp-2819	519	1	sci	sci	PROPN
fnp-2819	519	2	.	.	PROPN
fnp-2819	519	3	179	179	NUM
fnp-2819	519	4	,	,	PUNCT
fnp-2819	519	5	127	127	NUM
fnp-2819	519	6	-	-	SYM
fnp-2819	519	7	131	131	NUM
fnp-2819	519	8	.	.	PUNCT
fnp-2819	520	1	https://doi.org	https://doi.org	PROPN
fnp-2819	520	2	.	.	PUNCT
fnp-2819	521	1	10.1016	10.1016	NUM
fnp-2819	521	2	/	/	SYM
fnp-2819	521	3	s0022	s0022	NOUN
fnp-2819	521	4	-	-	PUNCT
fnp-2819	521	5	510x(00)00397	510x(00)00397	NUM
fnp-2819	521	6	-	-	PUNCT
fnp-2819	521	7	x.	x.	NOUN
fnp-2819	521	8	o'connor	o'connor	PROPN
fnp-2819	521	9	,	,	PUNCT
fnp-2819	521	10	r.a	r.a	PROPN
fnp-2819	521	11	.	.	PROPN
fnp-2819	521	12	,	,	PUNCT
fnp-2819	521	13	cambrook	cambrook	NOUN
fnp-2819	521	14	,	,	PUNCT
fnp-2819	521	15	h.	h.	PROPN
fnp-2819	521	16	,	,	PUNCT
fnp-2819	521	17	huettner	huettner	PROPN
fnp-2819	521	18	,	,	PUNCT
fnp-2819	521	19	k.	k.	PROPN
fnp-2819	521	20	,	,	PUNCT
fnp-2819	521	21	anderton	anderton	PROPN
fnp-2819	521	22	,	,	PUNCT
fnp-2819	521	23	s.m	s.m	PROPN
fnp-2819	521	24	.	.	PROPN
fnp-2819	521	25	,	,	PUNCT
fnp-2819	521	26	2013	2013	NUM
fnp-2819	521	27	.	.	PUNCT
fnp-2819	522	1	t	t	X
fnp-2819	522	2	-	-	PUNCT
fnp-2819	522	3	bet	bet	NOUN
fnp-2819	522	4	is	be	AUX
fnp-2819	522	5	essential	essential	ADJ
fnp-2819	522	6	for	for	ADP
fnp-2819	522	7	th1	th1	PROPN
fnp-2819	522	8	-	-	PUNCT
fnp-2819	522	9	mediated	mediate	VERB
fnp-2819	522	10	,	,	PUNCT
fnp-2819	522	11	but	but	CCONJ
fnp-2819	522	12	not	not	PART
fnp-2819	522	13	th17	th17	PROPN
fnp-2819	522	14	-	-	PUNCT
fnp-2819	522	15	mediated	mediate	VERB
fnp-2819	522	16	,	,	PUNCT
fnp-2819	522	17	cns	cns	PROPN
fnp-2819	522	18	autoimmune	autoimmune	ADJ
fnp-2819	522	19	disease	disease	NOUN
fnp-2819	522	20	.	.	PUNCT
fnp-2819	523	1	eur	eur	PROPN
fnp-2819	523	2	.	.	PUNCT
fnp-2819	524	1	j.	j.	PROPN
fnp-2819	524	2	immunol	immunol	PROPN
fnp-2819	524	3	.	.	PUNCT
fnp-2819	525	1	43	43	NUM
fnp-2819	525	2	,	,	PUNCT
fnp-2819	525	3	2818	2818	NUM
fnp-2819	525	4	-	-	SYM
fnp-2819	525	5	2823	2823	NUM
fnp-2819	525	6	.	.	PUNCT
fnp-2819	526	1	https://doi.org.10.1002	https://doi.org.10.1002	PROPN
fnp-2819	526	2	/	/	SYM
fnp-2819	526	3	eji.201343689	eji.201343689	PROPN
fnp-2819	526	4	.	.	PROPN
fnp-2819	526	5	okuda	okuda	PROPN
fnp-2819	526	6	,	,	PUNCT
fnp-2819	526	7	y.	y.	PROPN
fnp-2819	526	8	,	,	PUNCT
fnp-2819	526	9	sakoda	sakoda	PROPN
fnp-2819	526	10	,	,	PUNCT
fnp-2819	526	11	s.	s.	PROPN
fnp-2819	526	12	,	,	PUNCT
fnp-2819	526	13	yanagihara	yanagihara	NOUN
fnp-2819	526	14	,	,	PUNCT
fnp-2819	526	15	t.	t.	PROPN
fnp-2819	526	16	,	,	PUNCT
fnp-2819	526	17	1998	1998	NUM
fnp-2819	526	18	.	.	PUNCT
fnp-2819	527	1	the	the	DET
fnp-2819	527	2	pattern	pattern	NOUN
fnp-2819	527	3	of	of	ADP
fnp-2819	527	4	cytokine	cytokine	ADJ
fnp-2819	527	5	gene	gene	NOUN
fnp-2819	527	6	expression	expression	NOUN
fnp-2819	527	7	in	in	ADP
fnp-2819	527	8	lymphoid	lymphoid	ADJ
fnp-2819	527	9	organs	organ	NOUN
fnp-2819	527	10	and	and	CCONJ
fnp-2819	527	11	peripheral	peripheral	ADJ
fnp-2819	527	12	blood	blood	NOUN
fnp-2819	527	13	mononuclear	mononuclear	ADJ
fnp-2819	527	14	cells	cell	NOUN
fnp-2819	527	15	of	of	ADP
fnp-2819	527	16	mice	mouse	NOUN
fnp-2819	527	17	with	with	ADP
fnp-2819	527	18	experimental	experimental	ADJ
fnp-2819	527	19	allergic	allergic	ADJ
fnp-2819	527	20	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	527	21	.	.	PUNCT
fnp-2819	528	1	j.	j.	PROPN
fnp-2819	528	2	neuroimmunol	neuroimmunol	PROPN
fnp-2819	528	3	.	.	PUNCT
fnp-2819	529	1	87	87	NUM
fnp-2819	529	2	,	,	PUNCT
fnp-2819	529	3	147	147	NUM
fnp-2819	529	4	-	-	SYM
fnp-2819	529	5	155	155	NUM
fnp-2819	529	6	.	.	PUNCT
fnp-2819	530	1	pmid:9670856	pmid:9670856	NOUN
fnp-2819	530	2	.	.	PUNCT
fnp-2819	531	1	patel	patel	PROPN
fnp-2819	531	2	,	,	PUNCT
fnp-2819	531	3	t.	t.	PROPN
fnp-2819	531	4	,	,	PUNCT
fnp-2819	531	5	patel	patel	PROPN
fnp-2819	531	6	,	,	PUNCT
fnp-2819	531	7	v.	v.	PROPN
fnp-2819	531	8	,	,	PUNCT
fnp-2819	531	9	singh	singh	PROPN
fnp-2819	531	10	,	,	PUNCT
fnp-2819	531	11	r.	r.	PROPN
fnp-2819	531	12	,	,	PUNCT
fnp-2819	531	13	jayaraman	jayaraman	NOUN
fnp-2819	531	14	,	,	PUNCT
fnp-2819	531	15	s.	s.	PROPN
fnp-2819	531	16	,	,	PUNCT
fnp-2819	531	17	2011	2011	NUM
fnp-2819	531	18	.	.	PUNCT
fnp-2819	532	1	chromatin	chromatin	NOUN
fnp-2819	532	2	remodeling	remodeling	NOUN
fnp-2819	532	3	resets	reset	VERB
fnp-2819	532	4	the	the	DET
fnp-2819	532	5	immune	immune	ADJ
fnp-2819	532	6	system	system	NOUN
fnp-2819	532	7	to	to	PART
fnp-2819	532	8	protect	protect	VERB
fnp-2819	532	9	against	against	ADP
fnp-2819	532	10	autoimmune	autoimmune	ADJ
fnp-2819	532	11	diabetes	diabetes	NOUN
fnp-2819	532	12	in	in	ADP
fnp-2819	532	13	mice	mouse	NOUN
fnp-2819	532	14	.	.	PUNCT
fnp-2819	533	1	immunol	immunol	NOUN
fnp-2819	533	2	.	.	PUNCT
fnp-2819	534	1	cell	cell	NOUN
fnp-2819	534	2	biol	biol	PROPN
fnp-2819	534	3	.	.	PUNCT
fnp-2819	535	1	89:640	89:640	NUM
fnp-2819	535	2	-	-	PUNCT
fnp-2819	535	3	649	649	NUM
fnp-2819	535	4	.	.	PUNCT
fnp-2819	535	5	pmid:21321581	pmid:21321581	NOUN
fnp-2819	535	6	.	.	PUNCT
fnp-2819	535	7	pierson	pierson	PROPN
fnp-2819	535	8	,	,	PUNCT
fnp-2819	535	9	e.r	e.r	PROPN
fnp-2819	535	10	.	.	PROPN
fnp-2819	535	11	,	,	PUNCT
fnp-2819	535	12	goverman	goverman	NOUN
fnp-2819	535	13	,	,	PUNCT
fnp-2819	535	14	j.m	j.m	PROPN
fnp-2819	535	15	.	.	PROPN
fnp-2819	535	16	,	,	PUNCT
fnp-2819	535	17	2017	2017	NUM
fnp-2819	535	18	.	.	PUNCT
fnp-2819	536	1	gm	gm	PROPN
fnp-2819	536	2	-	-	PUNCT
fnp-2819	536	3	csf	csf	NOUN
fnp-2819	536	4	is	be	AUX
fnp-2819	536	5	not	not	PART
fnp-2819	536	6	essential	essential	ADJ
fnp-2819	536	7	for	for	ADP
fnp-2819	536	8	experimental	experimental	ADJ
fnp-2819	536	9	autoimmune	autoimmune	ADJ
fnp-2819	536	10	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	536	11	but	but	CCONJ
fnp-2819	536	12	promotes	promote	VERB
fnp-2819	536	13	brain	brain	NOUN
fnp-2819	536	14	-	-	PUNCT
fnp-2819	536	15	targeted	target	VERB
fnp-2819	536	16	disease	disease	NOUN
fnp-2819	536	17	.	.	PUNCT
fnp-2819	537	1	jci	jci	PROPN
fnp-2819	537	2	insight	insight	PROPN
fnp-2819	537	3	2	2	NUM
fnp-2819	537	4	,	,	PUNCT
fnp-2819	537	5	e92362	e92362	PROPN
fnp-2819	537	6	.	.	PUNCT
fnp-2819	538	1	https://doi.org.10.1172	https://doi.org.10.1172	NOUN
fnp-2819	538	2	/	/	SYM
fnp-2819	538	3	jci.insight.92362	jci.insight.92362	PROPN
fnp-2819	538	4	.	.	PUNCT
fnp-2819	539	1	ponomarev	ponomarev	PROPN
fnp-2819	539	2	,	,	PUNCT
fnp-2819	539	3	e.d	e.d	PROPN
fnp-2819	539	4	.	.	PROPN
fnp-2819	539	5	,	,	PUNCT
fnp-2819	539	6	maresz	maresz	PROPN
fnp-2819	539	7	,	,	PUNCT
fnp-2819	539	8	k.	k.	PROPN
fnp-2819	539	9	,	,	PUNCT
fnp-2819	539	10	tan	tan	PROPN
fnp-2819	539	11	,	,	PUNCT
fnp-2819	539	12	y.	y.	NOUN
fnp-2819	539	13	,	,	PUNCT
fnp-2819	539	14	dittel	dittel	NOUN
fnp-2819	539	15	,	,	PUNCT
fnp-2819	539	16	b.n	b.n	PROPN
fnp-2819	539	17	.	.	PROPN
fnp-2819	539	18	,	,	PUNCT
fnp-2819	539	19	2007	2007	NUM
fnp-2819	539	20	.	.	PUNCT
fnp-2819	540	1	cns	cns	NOUN
fnp-2819	540	2	-	-	PUNCT
fnp-2819	540	3	derived	derive	VERB
fnp-2819	540	4	interleukin-4	interleukin-4	NOUN
fnp-2819	540	5	is	be	AUX
fnp-2819	540	6	essential	essential	ADJ
fnp-2819	540	7	for	for	ADP
fnp-2819	540	8	the	the	DET
fnp-2819	540	9	regulation	regulation	NOUN
fnp-2819	540	10	of	of	ADP
fnp-2819	540	11	autoimmune	autoimmune	ADJ
fnp-2819	540	12	inflammation	inflammation	NOUN
fnp-2819	540	13	and	and	CCONJ
fnp-2819	540	14	induces	induce	VERB
fnp-2819	540	15	a	a	DET
fnp-2819	540	16	state	state	NOUN
fnp-2819	540	17	of	of	ADP
fnp-2819	540	18	alternative	alternative	ADJ
fnp-2819	540	19	activation	activation	NOUN
fnp-2819	540	20	in	in	ADP
fnp-2819	540	21	microglial	microglial	ADJ
fnp-2819	540	22	cells	cell	NOUN
fnp-2819	540	23	.	.	PUNCT
fnp-2819	541	1	j.	j.	PROPN
fnp-2819	541	2	neurosci	neurosci	PROPN
fnp-2819	541	3	.	.	PUNCT
fnp-2819	542	1	27	27	NUM
fnp-2819	542	2	,	,	PUNCT
fnp-2819	542	3	10714	10714	NUM
fnp-2819	542	4	-	-	SYM
fnp-2819	542	5	10721	10721	NUM
fnp-2819	542	6	.	.	PUNCT
fnp-2819	543	1	https://doi.org.10.1523	https://doi.org.10.1523	NOUN
fnp-2819	543	2	/	/	SYM
fnp-2819	543	3	jneurosci.1922	jneurosci.1922	PROPN
fnp-2819	543	4	-	-	PUNCT
fnp-2819	543	5	07.2007	07.2007	NUM
fnp-2819	543	6	.	.	PUNCT
fnp-2819	544	1	powell	powell	PROPN
fnp-2819	544	2	,	,	PUNCT
fnp-2819	544	3	n.d	n.d	PROPN
fnp-2819	544	4	.	.	PROPN
fnp-2819	544	5	,	,	PUNCT
fnp-2819	544	6	papenfuss	papenfuss	ADJ
fnp-2819	544	7	,	,	PUNCT
fnp-2819	544	8	t.l	t.l	PROPN
fnp-2819	544	9	.	.	PROPN
fnp-2819	544	10	,	,	PUNCT
fnp-2819	544	11	mcclain	mcclain	PROPN
fnp-2819	544	12	,	,	PUNCT
fnp-2819	544	13	m.a	m.a	PROPN
fnp-2819	544	14	.	.	PROPN
fnp-2819	544	15	,	,	PUNCT
fnp-2819	544	16	gienapp	gienapp	PROPN
fnp-2819	544	17	,	,	PUNCT
fnp-2819	544	18	i.e	i.e	ADJ
fnp-2819	544	19	,	,	PUNCT
fnp-2819	544	20	shawler	shawler	NOUN
fnp-2819	544	21	,	,	PUNCT
fnp-2819	544	22	t.m	t.m	PROPN
fnp-2819	544	23	.	.	PROPN
fnp-2819	544	24	,	,	PUNCT
fnp-2819	544	25	satoskar	satoskar	PROPN
fnp-2819	544	26	,	,	PUNCT
fnp-2819	544	27	a.r	a.r	PROPN
fnp-2819	544	28	.	.	PROPN
fnp-2819	544	29	,	,	PUNCT
fnp-2819	544	30	whitacre	whitacre	PROPN
fnp-2819	544	31	,	,	PUNCT
fnp-2819	544	32	c.c	c.c	PROPN
fnp-2819	544	33	.	.	PROPN
fnp-2819	544	34	,	,	PUNCT
fnp-2819	544	35	2005	2005	NUM
fnp-2819	544	36	.	.	PUNCT
fnp-2819	545	1	cutting	cut	VERB
fnp-2819	545	2	edge	edge	NOUN
fnp-2819	545	3	:	:	PUNCT
fnp-2819	545	4	macrophage	macrophage	ADJ
fnp-2819	545	5	migration	migration	NOUN
fnp-2819	545	6	inhibitory	inhibitory	ADJ
fnp-2819	545	7	factor	factor	NOUN
fnp-2819	545	8	is	be	AUX
fnp-2819	545	9	necessary	necessary	ADJ
fnp-2819	545	10	for	for	ADP
fnp-2819	545	11	progression	progression	NOUN
fnp-2819	545	12	of	of	ADP
fnp-2819	545	13	experimental	experimental	ADJ
fnp-2819	545	14	autoimmune	autoimmune	ADJ
fnp-2819	545	15	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	545	16	.	.	PUNCT
fnp-2819	546	1	j.	j.	PROPN
fnp-2819	546	2	immunol	immunol	PROPN
fnp-2819	546	3	.	.	PUNCT
fnp-2819	547	1	175	175	NUM
fnp-2819	547	2	,	,	PUNCT
fnp-2819	547	3	5611	5611	NUM
fnp-2819	547	4	-	-	SYM
fnp-2819	547	5	5614	5614	NUM
fnp-2819	547	6	.	.	PUNCT
fnp-2819	548	1	https://doi.org.10.4049	https://doi.org.10.4049	PROPN
fnp-2819	548	2	/	/	SYM
fnp-2819	548	3	jimmunol.175.9.5611	jimmunol.175.9.5611	PROPN
fnp-2819	548	4	.	.	PROPN
fnp-2819	548	5	raveney	raveney	PROPN
fnp-2819	548	6	,	,	PUNCT
fnp-2819	548	7	b.j	b.j	PROPN
fnp-2819	548	8	.	.	PROPN
fnp-2819	548	9	,	,	PUNCT
fnp-2819	548	10	oki	oki	PROPN
fnp-2819	548	11	,	,	PUNCT
fnp-2819	548	12	s.	s.	PROPN
fnp-2819	548	13	,	,	PUNCT
fnp-2819	548	14	hohjoh	hohjoh	PROPN
fnp-2819	548	15	,	,	PUNCT
fnp-2819	548	16	h.	h.	PROPN
fnp-2819	548	17	,	,	PUNCT
fnp-2819	548	18	nakamura	nakamura	PROPN
fnp-2819	548	19	,	,	PUNCT
fnp-2819	548	20	m.	m.	NOUN
fnp-2819	548	21	,	,	PUNCT
fnp-2819	548	22	sato	sato	PROPN
fnp-2819	548	23	,	,	PUNCT
fnp-2819	548	24	w.	w.	PROPN
fnp-2819	548	25	,	,	PUNCT
fnp-2819	548	26	murata	murata	PROPN
fnp-2819	548	27	,	,	PUNCT
fnp-2819	548	28	m.	m.	NOUN
fnp-2819	548	29	,	,	PUNCT
fnp-2819	548	30	yamamura	yamamura	NOUN
fnp-2819	548	31	,	,	PUNCT
fnp-2819	548	32	t.	t.	PROPN
fnp-2819	548	33	,	,	PUNCT
fnp-2819	548	34	2015	2015	NUM
fnp-2819	548	35	.	.	PUNCT
fnp-2819	549	1	eomesodermin	eomesodermin	NOUN
fnp-2819	549	2	-	-	PUNCT
fnp-2819	549	3	expressing	express	VERB
fnp-2819	549	4	t	t	NOUN
fnp-2819	549	5	-	-	PUNCT
fnp-2819	549	6	helper	helper	NOUN
fnp-2819	549	7	cells	cell	NOUN
fnp-2819	549	8	are	be	AUX
fnp-2819	549	9	essential	essential	ADJ
fnp-2819	549	10	for	for	ADP
fnp-2819	549	11	chronic	chronic	ADJ
fnp-2819	549	12	neuroinflammation	neuroinflammation	NOUN
fnp-2819	549	13	.	.	PUNCT
fnp-2819	550	1	nat	nat	PROPN
fnp-2819	550	2	.	.	PUNCT
fnp-2819	551	1	commun	commun	PROPN
fnp-2819	551	2	.	.	PROPN
fnp-2819	552	1	6	6	NUM
fnp-2819	552	2	,	,	PUNCT
fnp-2819	552	3	8437	8437	NUM
fnp-2819	552	4	.	.	PUNCT
fnp-2819	553	1	https://doi.org.10.1038	https://doi.org.10.1038	PROPN
fnp-2819	553	2	/	/	SYM
fnp-2819	553	3	ncomms9437	ncomms9437	PROPN
fnp-2819	553	4	.	.	PUNCT
fnp-2819	554	1	rempe	rempe	PROPN
fnp-2819	554	2	,	,	PUNCT
fnp-2819	554	3	r.g	r.g	PROPN
fnp-2819	554	4	.	.	PROPN
fnp-2819	554	5	,	,	PUNCT
fnp-2819	554	6	hartz	hartz	PROPN
fnp-2819	554	7	,	,	PUNCT
fnp-2819	554	8	a.m	a.m	PROPN
fnp-2819	554	9	,	,	PUNCT
fnp-2819	554	10	bauer	bauer	PROPN
fnp-2819	554	11	,	,	PUNCT
fnp-2819	554	12	b.	b.	PROPN
fnp-2819	554	13	,	,	PUNCT
fnp-2819	554	14	2016	2016	NUM
fnp-2819	554	15	.	.	PUNCT
fnp-2819	555	1	matrix	matrix	NOUN
fnp-2819	555	2	metalloproteinases	metalloproteinase	NOUN
fnp-2819	555	3	in	in	ADP
fnp-2819	555	4	the	the	DET
fnp-2819	555	5	brain	brain	NOUN
fnp-2819	555	6	and	and	CCONJ
fnp-2819	555	7	blood	blood	NOUN
fnp-2819	555	8	-	-	PUNCT
fnp-2819	555	9	brain	brain	NOUN
fnp-2819	555	10	barrier	barrier	NOUN
fnp-2819	555	11	:	:	PUNCT
fnp-2819	555	12	versatile	versatile	ADJ
fnp-2819	555	13	breakers	breaker	NOUN
fnp-2819	555	14	and	and	CCONJ
fnp-2819	555	15	markers	marker	NOUN
fnp-2819	555	16	.	.	PUNCT
fnp-2819	556	1	j.	j.	PROPN
fnp-2819	556	2	cereb	cereb	PROPN
fnp-2819	556	3	.	.	PUNCT
fnp-2819	556	4	blood	blood	NOUN
fnp-2819	556	5	flow	flow	NOUN
fnp-2819	556	6	metab	metab	NOUN
fnp-2819	556	7	.	.	PUNCT
fnp-2819	557	1	36	36	NUM
fnp-2819	557	2	,	,	PUNCT
fnp-2819	557	3	1481	1481	NUM
fnp-2819	557	4	-	-	SYM
fnp-2819	557	5	1507	1507	NUM
fnp-2819	557	6	.	.	PUNCT
fnp-2819	558	1	https://doi.org.10.1177/0271678x16655551	https://doi.org.10.1177/0271678x16655551	PROPN
fnp-2819	558	2	.	.	PROPN
fnp-2819	558	3	rivers	river	NOUN
fnp-2819	558	4	,	,	PUNCT
fnp-2819	558	5	t.m	t.m	PROPN
fnp-2819	558	6	.	.	PROPN
fnp-2819	558	7	,	,	PUNCT
fnp-2819	558	8	sprunt	sprunt	PROPN
fnp-2819	558	9	,	,	PUNCT
fnp-2819	558	10	d.h	d.h	PROPN
fnp-2819	558	11	,	,	PUNCT
fnp-2819	558	12	berry	berry	NOUN
fnp-2819	558	13	,	,	PUNCT
fnp-2819	558	14	g.p	g.p	PROPN
fnp-2819	558	15	.	.	PROPN
fnp-2819	558	16	,	,	PUNCT
fnp-2819	558	17	1933	1933	NUM
fnp-2819	558	18	.	.	PUNCT
fnp-2819	559	1	observations	observation	NOUN
fnp-2819	559	2	on	on	ADP
fnp-2819	559	3	attempts	attempt	NOUN
fnp-2819	559	4	to	to	PART
fnp-2819	559	5	produce	produce	VERB
fnp-2819	559	6	acute	acute	NOUN
fnp-2819	559	7	disseminated	disseminate	VERB
fnp-2819	559	8	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	559	9	in	in	ADP
fnp-2819	559	10	monkeys	monkey	NOUN
fnp-2819	559	11	.	.	PUNCT
fnp-2819	560	1	j.	j.	PROPN
fnp-2819	560	2	exp	exp	PROPN
fnp-2819	560	3	.	.	PROPN
fnp-2819	560	4	med	med	PROPN
fnp-2819	560	5	.	.	PUNCT
fnp-2819	561	1	58	58	NUM
fnp-2819	561	2	,	,	PUNCT
fnp-2819	561	3	39	39	NUM
fnp-2819	561	4	-	-	SYM
fnp-2819	561	5	53	53	NUM
fnp-2819	561	6	.	.	PUNCT
fnp-2819	562	1	https://doi.org.10.1084	https://doi.org.10.1084	NOUN
fnp-2819	562	2	/	/	SYM
fnp-2819	562	3	jem.58.1.39	jem.58.1.39	PROPN
fnp-2819	562	4	.	.	PUNCT
fnp-2819	563	1	schwartz	schwartz	PROPN
fnp-2819	563	2	,	,	PUNCT
fnp-2819	563	3	rh	rh	PROPN
fnp-2819	563	4	.	.	PROPN
fnp-2819	563	5	,	,	PUNCT
fnp-2819	563	6	mueller	mueller	PROPN
fnp-2819	563	7	,	,	PUNCT
fnp-2819	563	8	dl	dl	PROPN
fnp-2819	563	9	.	.	PROPN
fnp-2819	563	10	,	,	PUNCT
fnp-2819	563	11	jenkins	jenkins	PROPN
fnp-2819	563	12	,	,	PUNCT
fnp-2819	563	13	mk	mk	PROPN
fnp-2819	563	14	.	.	PROPN
fnp-2819	563	15	,	,	PUNCT
fnp-2819	563	16	quill	quill	PROPN
fnp-2819	563	17	,	,	PUNCT
fnp-2819	563	18	h.	h.	PROPN
fnp-2819	563	19	,	,	PUNCT
fnp-2819	563	20	1989	1989	NUM
fnp-2819	563	21	.	.	PUNCT
fnp-2819	564	1	t	t	NOUN
fnp-2819	564	2	-	-	PUNCT
fnp-2819	564	3	cell	cell	NOUN
fnp-2819	564	4	clonal	clonal	ADJ
fnp-2819	564	5	anergy	anergy	NOUN
fnp-2819	564	6	.	.	PUNCT
fnp-2819	565	1	cold	cold	ADJ
fnp-2819	565	2	spring	spring	NOUN
fnp-2819	565	3	harb	harb	PROPN
fnp-2819	565	4	.	.	PUNCT
fnp-2819	566	1	symp	symp	PROPN
fnp-2819	566	2	.	.	PUNCT
fnp-2819	567	1	quant	quant	NOUN
fnp-2819	567	2	.	.	PUNCT
fnp-2819	568	1	biol	biol	PROPN
fnp-2819	568	2	.	.	PUNCT
fnp-2819	569	1	54	54	NUM
fnp-2819	569	2	,	,	PUNCT
fnp-2819	569	3	605	605	NUM
fnp-2819	569	4	-	-	SYM
fnp-2819	569	5	610	610	NUM
fnp-2819	569	6	.	.	PUNCT
fnp-2819	570	1	pmid	pmid	PROPN
fnp-2819	570	2	2534840	2534840	NUM
fnp-2819	570	3	.	.	PUNCT
fnp-2819	571	1	slavin	slavin	NOUN
fnp-2819	571	2	,	,	PUNCT
fnp-2819	571	3	a.	a.	NOUN
fnp-2819	571	4	,	,	PUNCT
fnp-2819	571	5	ewing	ewing	PROPN
fnp-2819	571	6	,	,	PUNCT
fnp-2819	571	7	c.	c.	PROPN
fnp-2819	571	8	,	,	PUNCT
fnp-2819	571	9	liu	liu	PROPN
fnp-2819	571	10	,	,	PUNCT
fnp-2819	571	11	j.	j.	PROPN
fnp-2819	571	12	,	,	PUNCT
fnp-2819	571	13	ichikawa	ichikawa	PROPN
fnp-2819	571	14	m.	m.	NOUN
fnp-2819	571	15	,	,	PUNCT
fnp-2819	571	16	slavin	slavin	PROPN
fnp-2819	571	17	j.	j.	PROPN
fnp-2819	571	18	,	,	PUNCT
fnp-2819	571	19	bernanrd	bernanrd	PROPN
fnp-2819	571	20	,	,	PUNCT
fnp-2819	571	21	c.c	c.c	PROPN
fnp-2819	571	22	.	.	PROPN
fnp-2819	571	23	,	,	PUNCT
fnp-2819	571	24	1998	1998	NUM
fnp-2819	571	25	.	.	PUNCT
fnp-2819	572	1	induction	induction	NOUN
fnp-2819	572	2	of	of	ADP
fnp-2819	572	3	a	a	DET
fnp-2819	572	4	multiple	multiple	ADJ
fnp-2819	572	5	sclerosis	sclerosis	NOUN
fnp-2819	572	6	-	-	PUNCT
fnp-2819	572	7	like	like	ADJ
fnp-2819	572	8	disease	disease	NOUN
fnp-2819	572	9	in	in	ADP
fnp-2819	572	10	mice	mouse	NOUN
fnp-2819	572	11	with	with	ADP
fnp-2819	572	12	an	an	DET
fnp-2819	572	13	immunodominant	immunodominant	ADJ
fnp-2819	572	14	epitope	epitope	NOUN
fnp-2819	572	15	of	of	ADP
fnp-2819	572	16	myelin	myelin	ADJ
fnp-2819	572	17	oligodendrocyte	oligodendrocyte	NOUN
fnp-2819	572	18	glycoprotein	glycoprotein	NOUN
fnp-2819	572	19	.	.	PUNCT
fnp-2819	573	1	autoimmunity	autoimmunity	NOUN
fnp-2819	573	2	28	28	NUM
fnp-2819	573	3	,	,	PUNCT
fnp-2819	573	4	109	109	NUM
fnp-2819	573	5	-	-	SYM
fnp-2819	573	6	120	120	NUM
fnp-2819	573	7	.	.	PUNCT
fnp-2819	574	1	https://doi.org.10.3109/08916939809003872	https://doi.org.10.3109/08916939809003872	X
fnp-2819	574	2	.	.	PUNCT
fnp-2819	575	1	steinman	steinman	PROPN
fnp-2819	575	2	,	,	PUNCT
fnp-2819	575	3	l.	l.	PROPN
fnp-2819	575	4	,	,	PUNCT
fnp-2819	575	5	2015	2015	NUM
fnp-2819	575	6	.	.	PUNCT
fnp-2819	576	1	the	the	DET
fnp-2819	576	2	re	re	NOUN
fnp-2819	576	3	-	-	NOUN
fnp-2819	576	4	emergence	emergence	NOUN
fnp-2819	576	5	of	of	ADP
fnp-2819	576	6	antigen	antigen	NOUN
fnp-2819	576	7	-	-	PUNCT
fnp-2819	576	8	specific	specific	ADJ
fnp-2819	576	9	tolerance	tolerance	NOUN
fnp-2819	576	10	as	as	ADP
fnp-2819	576	11	a	a	DET
fnp-2819	576	12	potential	potential	ADJ
fnp-2819	576	13	therapy	therapy	NOUN
fnp-2819	576	14	for	for	ADP
fnp-2819	576	15	ms	ms	PROPN
fnp-2819	576	16	.	.	PROPN
fnp-2819	576	17	mult	mult	PROPN
fnp-2819	576	18	.	.	PROPN
fnp-2819	576	19	scler	scler	PROPN
fnp-2819	576	20	.	.	PUNCT
fnp-2819	577	1	21	21	NUM
fnp-2819	577	2	,	,	PUNCT
fnp-2819	577	3	1223	1223	NUM
fnp-2819	577	4	-	-	SYM
fnp-2819	577	5	1238	1238	NUM
fnp-2819	577	6	.	.	PUNCT
fnp-2819	578	1	https://doi.org.10.1177/1352458515581441	https://doi.org.10.1177/1352458515581441	ADV
fnp-2819	578	2	.	.	PUNCT
fnp-2819	579	1	szczuciński	szczuciński	PROPN
fnp-2819	579	2	,	,	PUNCT
fnp-2819	579	3	a.	a.	NOUN
fnp-2819	579	4	,	,	PUNCT
fnp-2819	579	5	losy	losy	NOUN
fnp-2819	579	6	,	,	PUNCT
fnp-2819	579	7	j.	j.	PROPN
fnp-2819	579	8	,	,	PUNCT
fnp-2819	579	9	2004	2004	NUM
fnp-2819	579	10	.	.	PUNCT
fnp-2819	580	1	long	long	ADJ
fnp-2819	580	2	-	-	PUNCT
fnp-2819	580	3	term	term	NOUN
fnp-2819	580	4	effect	effect	NOUN
fnp-2819	580	5	of	of	ADP
fnp-2819	580	6	ifn	ifn	PROPN
fnp-2819	580	7	-	-	PUNCT
fnp-2819	580	8	beta	beta	NOUN
fnp-2819	580	9	1a	1a	X
fnp-2819	580	10	therapy	therapy	NOUN
fnp-2819	580	11	on	on	ADP
fnp-2819	580	12	ccl2	ccl2	NOUN
fnp-2819	580	13	(	(	PUNCT
fnp-2819	580	14	mcp-1	mcp-1	NOUN
fnp-2819	580	15	)	)	PUNCT
fnp-2819	580	16	chemokine	chemokine	ADJ
fnp-2819	580	17	in	in	ADP
fnp-2819	580	18	patients	patient	NOUN
fnp-2819	580	19	with	with	ADP
fnp-2819	580	20	multiple	multiple	ADJ
fnp-2819	580	21	sclerosis	sclerosis	NOUN
fnp-2819	580	22	.	.	PUNCT
fnp-2819	581	1	folia	folia	PROPN
fnp-2819	581	2	neuropathol	neuropathol	PROPN
fnp-2819	581	3	.	.	PUNCT
fnp-2819	582	1	42	42	NUM
fnp-2819	582	2	,	,	PUNCT
fnp-2819	582	3	15	15	NUM
fnp-2819	582	4	-	-	SYM
fnp-2819	582	5	18	18	NUM
fnp-2819	582	6	.	.	PUNCT
fnp-2819	582	7	pmid:15119740	pmid:15119740	PROPN
fnp-2819	582	8	.	.	PUNCT
fnp-2819	582	9	tao	tao	PROPN
fnp-2819	582	10	,	,	PUNCT
fnp-2819	582	11	r.	r.	PROPN
fnp-2819	582	12	,	,	PUNCT
fnp-2819	582	13	de	de	X
fnp-2819	582	14	zoeten	zoeten	NOUN
fnp-2819	582	15	,	,	PUNCT
fnp-2819	582	16	e.f	e.f	PROPN
fnp-2819	582	17	.	.	PROPN
fnp-2819	582	18	,	,	PUNCT
fnp-2819	582	19	ozkaynak	ozkaynak	PROPN
fnp-2819	582	20	,	,	PUNCT
fnp-2819	582	21	e.	e.	PROPN
fnp-2819	582	22	,	,	PUNCT
fnp-2819	582	23	chen	chen	PROPN
fnp-2819	582	24	,	,	PUNCT
fnp-2819	582	25	c.	c.	PROPN
fnp-2819	582	26	,	,	PUNCT
fnp-2819	582	27	wang	wang	PROPN
fnp-2819	582	28	,	,	PUNCT
fnp-2819	582	29	l.	l.	PROPN
fnp-2819	582	30	,	,	PUNCT
fnp-2819	582	31	porrett	porrett	ADJ
fnp-2819	582	32	,	,	PUNCT
fnp-2819	582	33	p.m.	p.m.	NOUN
fnp-2819	582	34	,	,	PUNCT
fnp-2819	582	35	li	li	PROPN
fnp-2819	582	36	,	,	PUNCT
fnp-2819	582	37	b.	b.	PROPN
fnp-2819	582	38	,	,	PUNCT
fnp-2819	582	39	turka	turka	PROPN
fnp-2819	582	40	,	,	PUNCT
fnp-2819	582	41	l.a	l.a	PROPN
fnp-2819	582	42	.	.	PROPN
fnp-2819	582	43	,	,	PUNCT
fnp-2819	582	44	olson	olson	PROPN
fnp-2819	582	45	,	,	PUNCT
fnp-2819	582	46	e.n	e.n	PROPN
fnp-2819	582	47	.	.	PROPN
fnp-2819	582	48	,	,	PUNCT
fnp-2819	582	49	greene	greene	PROPN
fnp-2819	582	50	,	,	PUNCT
fnp-2819	582	51	m.i	m.i	PROPN
fnp-2819	582	52	.	.	PROPN
fnp-2819	582	53	,	,	PUNCT
fnp-2819	582	54	wells	wells	PROPN
fnp-2819	582	55	,	,	PUNCT
fnp-2819	582	56	a.d	a.d	PROPN
fnp-2819	582	57	.	.	PROPN
fnp-2819	582	58	,	,	PUNCT
fnp-2819	582	59	hancock	hancock	PROPN
fnp-2819	582	60	,	,	PUNCT
fnp-2819	582	61	w.w	w.w	PROPN
fnp-2819	582	62	.	.	PROPN
fnp-2819	582	63	,	,	PUNCT
fnp-2819	582	64	2007	2007	NUM
fnp-2819	582	65	.	.	PUNCT
fnp-2819	583	1	deacetylase	deacetylase	NOUN
fnp-2819	583	2	inhibition	inhibition	NOUN
fnp-2819	583	3	promotes	promote	VERB
fnp-2819	583	4	the	the	DET
fnp-2819	583	5	generation	generation	NOUN
fnp-2819	583	6	and	and	CCONJ
fnp-2819	583	7	function	function	NOUN
fnp-2819	583	8	of	of	ADP
fnp-2819	583	9	regulatory	regulatory	ADJ
fnp-2819	583	10	t	t	NOUN
fnp-2819	583	11	cells	cell	NOUN
fnp-2819	583	12	.	.	PUNCT
fnp-2819	584	1	nat	nat	PROPN
fnp-2819	584	2	.	.	PUNCT
fnp-2819	585	1	med	med	PROPN
fnp-2819	585	2	.	.	PROPN
fnp-2819	585	3	13	13	NUM
fnp-2819	585	4	,	,	PUNCT
fnp-2819	585	5	1299	1299	NUM
fnp-2819	585	6	-	-	SYM
fnp-2819	585	7	1307	1307	NUM
fnp-2819	585	8	.	.	PUNCT
fnp-2819	586	1	https://doi.org.10.1038	https://doi.org.10.1038	PROPN
fnp-2819	586	2	/	/	SYM
fnp-2819	586	3	nm1652	nm1652	PROPN
fnp-2819	586	4	.	.	PUNCT
fnp-2819	587	1	tintore	tintore	NOUN
fnp-2819	587	2	,	,	PUNCT
fnp-2819	587	3	m.	m.	NOUN
fnp-2819	587	4	,	,	PUNCT
fnp-2819	587	5	vidal	vidal	NOUN
fnp-2819	587	6	-	-	PUNCT
fnp-2819	587	7	jordana	jordana	PROPN
fnp-2819	587	8	,	,	PUNCT
fnp-2819	587	9	a.	a.	NOUN
fnp-2819	587	10	,	,	PUNCT
fnp-2819	587	11	sastre	sastre	NOUN
fnp-2819	587	12	-	-	PUNCT
fnp-2819	587	13	garriga	garriga	NOUN
fnp-2819	587	14	,	,	PUNCT
fnp-2819	587	15	j.	j.	PROPN
fnp-2819	587	16	,	,	PUNCT
fnp-2819	587	17	2019	2019	NUM
fnp-2819	587	18	.	.	PUNCT
fnp-2819	588	1	treatment	treatment	NOUN
fnp-2819	588	2	of	of	ADP
fnp-2819	588	3	multiple	multiple	ADJ
fnp-2819	588	4	sclerosis	sclerosis	NOUN
fnp-2819	588	5	success	success	NOUN
fnp-2819	588	6	from	from	ADP
fnp-2819	588	7	bench	bench	NOUN
fnp-2819	588	8	to	to	ADP
fnp-2819	588	9	bedside	bedside	NOUN
fnp-2819	588	10	.	.	PUNCT
fnp-2819	589	1	nat	nat	PROPN
fnp-2819	589	2	.	.	PUNCT
fnp-2819	589	3	rev	rev	PROPN
fnp-2819	589	4	.	.	PUNCT
fnp-2819	590	1	neurol	neurol	PROPN
fnp-2819	590	2	.	.	PUNCT
fnp-2819	591	1	15	15	NUM
fnp-2819	591	2	,	,	PUNCT
fnp-2819	591	3	53	53	NUM
fnp-2819	591	4	-	-	SYM
fnp-2819	591	5	58	58	NUM
fnp-2819	591	6	.	.	PUNCT
fnp-2819	592	1	https://doi.org/10.1038/s41582-018-0082-z	https://doi.org/10.1038/s41582-018-0082-z	NOUN
fnp-2819	592	2	.	.	PUNCT
fnp-2819	593	1	tran	tran	PROPN
fnp-2819	593	2	,	,	PUNCT
fnp-2819	593	3	e.h	e.h	PROPN
fnp-2819	593	4	.	.	PROPN
fnp-2819	593	5	,	,	PUNCT
fnp-2819	593	6	hardin	hardin	PROPN
fnp-2819	593	7	-	-	PUNCT
fnp-2819	593	8	pouzet	pouzet	PROPN
fnp-2819	593	9	,	,	PUNCT
fnp-2819	593	10	h.	h.	PROPN
fnp-2819	593	11	,	,	PUNCT
fnp-2819	593	12	verge	verge	NOUN
fnp-2819	593	13	,	,	PUNCT
fnp-2819	593	14	g.	g.	PROPN
fnp-2819	593	15	,	,	PUNCT
fnp-2819	593	16	owens	owens	PROPN
fnp-2819	593	17	,	,	PUNCT
fnp-2819	593	18	t.	t.	PROPN
fnp-2819	593	19	,	,	PUNCT
fnp-2819	593	20	1997	1997	NUM
fnp-2819	593	21	.	.	PUNCT
fnp-2819	594	1	astrocytes	astrocyte	NOUN
fnp-2819	594	2	and	and	CCONJ
fnp-2819	594	3	microglia	microglia	NOUN
fnp-2819	594	4	express	express	VERB
fnp-2819	594	5	inducible	inducible	ADJ
fnp-2819	594	6	nitric	nitric	ADJ
fnp-2819	594	7	oxide	oxide	NOUN
fnp-2819	594	8	synthase	synthase	NOUN
fnp-2819	594	9	in	in	ADP
fnp-2819	594	10	mice	mouse	NOUN
fnp-2819	594	11	with	with	ADP
fnp-2819	594	12	experimental	experimental	ADJ
fnp-2819	594	13	allergic	allergic	ADJ
fnp-2819	594	14	encephalomyelitis	encephalomyelitis	NOUN
fnp-2819	594	15	.	.	PUNCT
fnp-2819	595	1	j.	j.	PROPN
fnp-2819	595	2	neuroimmunol	neuroimmunol	PROPN
fnp-2819	595	3	.	.	PUNCT
fnp-2819	596	1	74	74	NUM
fnp-2819	596	2	,	,	PUNCT
fnp-2819	596	3	121	121	NUM
fnp-2819	596	4	-	-	SYM
fnp-2819	596	5	129	129	NUM
fnp-2819	596	6	.	.	PUNCT
fnp-2819	597	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	597	2	/	/	SYM
fnp-2819	597	3	s0165	s0165	VERB
fnp-2819	597	4	-	-	PUNCT
fnp-2819	597	5	5728(96)00215	5728(96)00215	NOUN
fnp-2819	597	6	-	-	PUNCT
fnp-2819	597	7	9	9	NUM
fnp-2819	597	8	.	.	PUNCT
fnp-2819	598	1	van	van	NOUN
fnp-2819	598	2	lint	lint	PROPN
fnp-2819	598	3	,	,	PUNCT
fnp-2819	598	4	c.	c.	PROPN
fnp-2819	598	5	,	,	PUNCT
fnp-2819	598	6	emiliani	emiliani	PROPN
fnp-2819	598	7	,	,	PUNCT
fnp-2819	598	8	s.	s.	PROPN
fnp-2819	598	9	,	,	PUNCT
fnp-2819	598	10	verdin	verdin	PROPN
fnp-2819	598	11	,	,	PUNCT
fnp-2819	598	12	e.	e.	PROPN
fnp-2819	598	13	,	,	PUNCT
fnp-2819	598	14	1996	1996	NUM
fnp-2819	598	15	.	.	PUNCT
fnp-2819	599	1	the	the	DET
fnp-2819	599	2	expression	expression	NOUN
fnp-2819	599	3	of	of	ADP
fnp-2819	599	4	a	a	DET
fnp-2819	599	5	small	small	ADJ
fnp-2819	599	6	fraction	fraction	NOUN
fnp-2819	599	7	of	of	ADP
fnp-2819	599	8	cellular	cellular	ADJ
fnp-2819	599	9	genes	gene	NOUN
fnp-2819	599	10	is	be	AUX
fnp-2819	599	11	changed	change	VERB
fnp-2819	599	12	in	in	ADP
fnp-2819	599	13	response	response	NOUN
fnp-2819	599	14	to	to	ADP
fnp-2819	599	15	histone	histone	NOUN
fnp-2819	599	16	hyperacetylation	hyperacetylation	NOUN
fnp-2819	599	17	.	.	PUNCT
fnp-2819	600	1	gene	gene	NOUN
fnp-2819	600	2	expr	expr	NOUN
fnp-2819	600	3	.	.	PUNCT
fnp-2819	601	1	5	5	NUM
fnp-2819	601	2	,	,	PUNCT
fnp-2819	601	3	245	245	NUM
fnp-2819	601	4	-	-	SYM
fnp-2819	601	5	253	253	NUM
fnp-2819	601	6	.	.	PUNCT
fnp-2819	602	1	pmid:8723390	pmid:8723390	NOUN
fnp-2819	602	2	.	.	PUNCT
fnp-2819	603	1	villagra	villagra	PROPN
fnp-2819	603	2	,	,	PUNCT
fnp-2819	603	3	a.	a.	PROPN
fnp-2819	603	4	,	,	PUNCT
fnp-2819	603	5	cheng	cheng	PROPN
fnp-2819	603	6	,	,	PUNCT
fnp-2819	603	7	f.	f.	PROPN
fnp-2819	603	8	,	,	PUNCT
fnp-2819	603	9	wang	wang	PROPN
fnp-2819	603	10	,	,	PUNCT
fnp-2819	603	11	h.w	h.w	PROPN
fnp-2819	603	12	.	.	PROPN
fnp-2819	603	13	,	,	PUNCT
fnp-2819	603	14	suarez	suarez	PROPN
fnp-2819	603	15	,	,	PUNCT
fnp-2819	603	16	i.	i.	PROPN
fnp-2819	603	17	,	,	PUNCT
fnp-2819	603	18	glozak	glozak	PROPN
fnp-2819	603	19	,	,	PUNCT
fnp-2819	603	20	m.	m.	NOUN
fnp-2819	603	21	,	,	PUNCT
fnp-2819	603	22	maurin	maurin	NOUN
fnp-2819	603	23	,	,	PUNCT
fnp-2819	603	24	m.	m.	NOUN
fnp-2819	603	25	,	,	PUNCT
fnp-2819	603	26	nguyen	nguyen	PROPN
fnp-2819	603	27	,	,	PUNCT
fnp-2819	603	28	d.	d.	PROPN
fnp-2819	603	29	,	,	PUNCT
fnp-2819	603	30	wright	wright	PROPN
fnp-2819	603	31	,	,	PUNCT
fnp-2819	603	32	k.l	k.l	PROPN
fnp-2819	603	33	.	.	PROPN
fnp-2819	603	34	,	,	PUNCT
fnp-2819	603	35	atadja	atadja	PROPN
fnp-2819	603	36	,	,	PUNCT
fnp-2819	603	37	p.w	p.w	PROPN
fnp-2819	603	38	.	.	PROPN
fnp-2819	603	39	,	,	PUNCT
fnp-2819	603	40	bhalla	bhalla	PROPN
fnp-2819	603	41	,	,	PUNCT
fnp-2819	603	42	k.	k.	PROPN
fnp-2819	603	43	,	,	PUNCT
fnp-2819	603	44	pinilla	pinilla	NOUN
fnp-2819	603	45	-	-	PUNCT
fnp-2819	603	46	ibarz	ibarz	PROPN
fnp-2819	603	47	,	,	PUNCT
fnp-2819	603	48	j.	j.	PROPN
fnp-2819	603	49	,	,	PUNCT
fnp-2819	603	50	seto	seto	NOUN
fnp-2819	603	51	,	,	PUNCT
fnp-2819	603	52	e.	e.	PROPN
fnp-2819	603	53	,	,	PUNCT
fnp-2819	603	54	sotomayor	sotomayor	PROPN
fnp-2819	603	55	,	,	PUNCT
fnp-2819	603	56	e.m	e.m	PROPN
fnp-2819	603	57	.	.	PROPN
fnp-2819	603	58	,	,	PUNCT
fnp-2819	603	59	2009	2009	NUM
fnp-2819	603	60	.	.	PUNCT
fnp-2819	604	1	the	the	DET
fnp-2819	604	2	histone	histone	PROPN
fnp-2819	604	3	deacetylase	deacetylase	PROPN
fnp-2819	604	4	hdac11	hdac11	NOUN
fnp-2819	604	5	regulates	regulate	VERB
fnp-2819	604	6	the	the	DET
fnp-2819	604	7	expression	expression	NOUN
fnp-2819	604	8	of	of	ADP
fnp-2819	604	9	interleukin	interleukin	NOUN
fnp-2819	604	10	10	10	NUM
fnp-2819	604	11	and	and	CCONJ
fnp-2819	604	12	immune	immune	ADJ
fnp-2819	604	13	tolerance	tolerance	NOUN
fnp-2819	604	14	.	.	PUNCT
fnp-2819	605	1	nat	nat	NOUN
fnp-2819	605	2	.	.	PUNCT
fnp-2819	606	1	immunol	immunol	PROPN
fnp-2819	606	2	.	.	PUNCT
fnp-2819	607	1	10	10	NUM
fnp-2819	607	2	,	,	PUNCT
fnp-2819	607	3	92	92	NUM
fnp-2819	607	4	-	-	SYM
fnp-2819	607	5	100	100	NUM
fnp-2819	607	6	.	.	PUNCT
fnp-2819	607	7	https://doi.org.10.1038	https://doi.org.10.1038	PROPN
fnp-2819	607	8	/	/	SYM
fnp-2819	607	9	ni.1673	ni.1673	PROPN
fnp-2819	607	10	.	.	PROPN
fnp-2819	607	11	wingerchuk	wingerchuk	PROPN
fnp-2819	607	12	,	,	PUNCT
fnp-2819	607	13	d.m	d.m	PROPN
fnp-2819	607	14	.	.	PROPN
fnp-2819	607	15	,	,	PUNCT
fnp-2819	607	16	carter	carter	PROPN
fnp-2819	607	17	,	,	PUNCT
fnp-2819	607	18	j.l	j.l	PROPN
fnp-2819	607	19	.	.	PROPN
fnp-2819	607	20	,	,	PUNCT
fnp-2819	607	21	2014	2014	NUM
fnp-2819	607	22	.	.	PUNCT
fnp-2819	608	1	multiple	multiple	ADJ
fnp-2819	608	2	sclerosis	sclerosis	NOUN
fnp-2819	608	3	:	:	PUNCT
fnp-2819	608	4	current	current	ADJ
fnp-2819	608	5	and	and	CCONJ
fnp-2819	608	6	emerging	emerge	VERB
fnp-2819	608	7	disease	disease	NOUN
fnp-2819	608	8	-	-	PUNCT
fnp-2819	608	9	modifying	modify	VERB
fnp-2819	608	10	therapies	therapy	NOUN
fnp-2819	608	11	and	and	CCONJ
fnp-2819	608	12	treatment	treatment	NOUN
fnp-2819	608	13	strategies	strategy	NOUN
fnp-2819	608	14	.	.	PUNCT
fnp-2819	609	1	mayo	mayo	PROPN
fnp-2819	609	2	clin	clin	PROPN
fnp-2819	609	3	.	.	PUNCT
fnp-2819	610	1	proc	proc	PROPN
fnp-2819	610	2	.	.	PROPN
fnp-2819	610	3	89	89	NUM
fnp-2819	610	4	,	,	PUNCT
fnp-2819	610	5	225	225	NUM
fnp-2819	610	6	-	-	SYM
fnp-2819	610	7	240	240	NUM
fnp-2819	610	8	.	.	PUNCT
fnp-2819	611	1	https://doi.org.10.1016	https://doi.org.10.1016	PROPN
fnp-2819	611	2	/	/	SYM
fnp-2819	611	3	j.mayocp.2013.11.002	j.mayocp.2013.11.002	PROPN
fnp-2819	611	4	.	.	PUNCT
fnp-2819	612	1	copyright	copyright	NOUN
fnp-2819	612	2	:	:	PUNCT
fnp-2819	612	3	©	©	PROPN
fnp-2819	612	4	2020	2020	NUM
fnp-2819	612	5	the	the	DET
fnp-2819	612	6	author(s	author(s	NOUN
fnp-2819	612	7	)	)	PUNCT
fnp-2819	612	8	.	.	PUNCT
fnp-2819	613	1	this	this	PRON
fnp-2819	613	2	is	be	AUX
fnp-2819	613	3	an	an	DET
fnp-2819	613	4	open	open	ADJ
fnp-2819	613	5	access	access	NOUN
fnp-2819	613	6	article	article	NOUN
fnp-2819	613	7	distributed	distribute	VERB
fnp-2819	613	8	under	under	ADP
fnp-2819	613	9	the	the	DET
fnp-2819	613	10	terms	term	NOUN
fnp-2819	613	11	of	of	ADP
fnp-2819	613	12	the	the	DET
fnp-2819	613	13	creative	creative	ADJ
fnp-2819	613	14	commons	common	NOUN
fnp-2819	613	15	attribution	attribution	NOUN
fnp-2819	613	16	4.0	4.0	NUM
fnp-2819	613	17	international	international	ADJ
fnp-2819	613	18	license	license	NOUN
fnp-2819	613	19	(	(	PUNCT
fnp-2819	613	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-2819	613	21	)	)	PUNCT
fnp-2819	613	22	,	,	PUNCT
fnp-2819	613	23	which	which	PRON
fnp-2819	613	24	permits	permit	VERB
fnp-2819	613	25	unrestricted	unrestricted	ADJ
fnp-2819	613	26	use	use	NOUN
fnp-2819	613	27	,	,	PUNCT
fnp-2819	613	28	distribution	distribution	NOUN
fnp-2819	613	29	,	,	PUNCT
fnp-2819	613	30	and	and	CCONJ
fnp-2819	613	31	reproduction	reproduction	NOUN
fnp-2819	613	32	in	in	ADP
fnp-2819	613	33	any	any	DET
fnp-2819	613	34	medium	medium	NOUN
fnp-2819	613	35	,	,	PUNCT
fnp-2819	613	36	provided	provide	VERB
fnp-2819	613	37	the	the	DET
fnp-2819	613	38	original	original	ADJ
fnp-2819	613	39	author	author	NOUN
fnp-2819	613	40	and	and	CCONJ
fnp-2819	613	41	source	source	NOUN
fnp-2819	613	42	are	be	AUX
fnp-2819	613	43	credited	credit	VERB
fnp-2819	613	44	,	,	PUNCT
fnp-2819	613	45	a	a	DET
fnp-2819	613	46	link	link	NOUN
fnp-2819	613	47	to	to	ADP
fnp-2819	613	48	the	the	DET
fnp-2819	613	49	creative	creative	ADJ
fnp-2819	613	50	commons	common	NOUN
fnp-2819	613	51	license	license	NOUN
fnp-2819	613	52	is	be	AUX
fnp-2819	613	53	provided	provide	VERB
fnp-2819	613	54	,	,	PUNCT
fnp-2819	613	55	and	and	CCONJ
fnp-2819	613	56	any	any	DET
fnp-2819	613	57	changes	change	NOUN
fnp-2819	613	58	are	be	AUX
fnp-2819	613	59	indicated	indicate	VERB
fnp-2819	613	60	.	.	PUNCT
fnp-2819	614	1	the	the	DET
fnp-2819	614	2	creative	creative	ADJ
fnp-2819	614	3	commons	common	NOUN
fnp-2819	614	4	public	public	ADJ
fnp-2819	614	5	domain	domain	NOUN
fnp-2819	614	6	dedication	dedication	NOUN
fnp-2819	614	7	waiver	waiver	NOUN
fnp-2819	614	8	(	(	PUNCT
fnp-2819	614	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-2819	614	10	)	)	PUNCT
fnp-2819	614	11	applies	apply	VERB
fnp-2819	614	12	to	to	ADP
fnp-2819	614	13	the	the	DET
fnp-2819	614	14	data	datum	NOUN
fnp-2819	614	15	made	make	VERB
fnp-2819	614	16	available	available	ADJ
fnp-2819	614	17	in	in	ADP
fnp-2819	614	18	this	this	DET
fnp-2819	614	19	article	article	NOUN
fnp-2819	614	20	,	,	PUNCT
fnp-2819	614	21	unless	unless	SCONJ
fnp-2819	614	22	otherwise	otherwise	ADV
fnp-2819	614	23	stated	state	VERB
fnp-2819	614	24	.	.	PUNCT
