id	sid	tid	token	lemma	pos
fnp-2845	1	1	clustering	clustering	NOUN
fnp-2845	1	2	of	of	ADP
fnp-2845	1	3	activated	activate	VERB
fnp-2845	1	4	microglia	microglia	NOUN
fnp-2845	1	5	occurs	occur	VERB
fnp-2845	1	6	before	before	ADP
fnp-2845	1	7	the	the	DET
fnp-2845	1	8	formation	formation	NOUN
fnp-2845	1	9	of	of	ADP
fnp-2845	1	10	dystrophic	dystrophic	ADJ
fnp-2845	1	11	neurites	neurite	NOUN
fnp-2845	1	12	in	in	ADP
fnp-2845	1	13	the	the	DET
fnp-2845	1	14	evolution	evolution	NOUN
fnp-2845	1	15	of	of	ADP
fnp-2845	1	16	aβ	aβ	DET
fnp-2845	1	17	plaques	plaque	NOUN
fnp-2845	1	18	in	in	ADP
fnp-2845	1	19	alzheimer	alzheimer	PROPN
fnp-2845	1	20	’s	’s	PART
fnp-2845	1	21	disease	disease	NOUN
fnp-2845	1	22	.	.	PUNCT
fnp-2845	2	1	feel	feel	VERB
fnp-2845	2	2	free	free	ADJ
fnp-2845	2	3	to	to	PART
fnp-2845	2	4	add	add	VERB
fnp-2845	2	5	comments	comment	NOUN
fnp-2845	2	6	by	by	ADP
fnp-2845	2	7	clicking	click	VERB
fnp-2845	2	8	these	these	DET
fnp-2845	2	9	icons	icon	NOUN
fnp-2845	2	10	on	on	ADP
fnp-2845	2	11	the	the	DET
fnp-2845	2	12	sidebar	sidebar	NOUN
fnp-2845	2	13	free	free	ADJ
fnp-2845	2	14	neuropathology	neuropathology	NOUN
fnp-2845	2	15	1:20	1:20	NUM
fnp-2845	2	16	(	(	PUNCT
fnp-2845	2	17	2020	2020	NUM
fnp-2845	2	18	)	)	PUNCT
fnp-2845	2	19	original	original	ADJ
fnp-2845	2	20	paper	paper	NOUN
fnp-2845	2	21	clustering	clustering	NOUN
fnp-2845	2	22	of	of	ADP
fnp-2845	2	23	activated	activate	VERB
fnp-2845	2	24	microglia	microglia	NOUN
fnp-2845	2	25	occurs	occur	VERB
fnp-2845	2	26	before	before	ADP
fnp-2845	2	27	the	the	DET
fnp-2845	2	28	formation	formation	NOUN
fnp-2845	2	29	of	of	ADP
fnp-2845	2	30	dystrophic	dystrophic	ADJ
fnp-2845	2	31	neurites	neurite	NOUN
fnp-2845	2	32	in	in	ADP
fnp-2845	2	33	the	the	DET
fnp-2845	2	34	evolution	evolution	NOUN
fnp-2845	2	35	of	of	ADP
fnp-2845	2	36	aβ	aβ	DET
fnp-2845	2	37	plaques	plaque	NOUN
fnp-2845	2	38	in	in	ADP
fnp-2845	2	39	alzheimer	alzheimer	PROPN
fnp-2845	2	40	’s	’s	PART
fnp-2845	2	41	disease	disease	NOUN
fnp-2845	2	42	.	.	PUNCT
fnp-2845	3	1	patrick	patrick	PROPN
fnp-2845	3	2	jarmo	jarmo	PROPN
fnp-2845	3	3	paasila	paasila	PROPN
fnp-2845	3	4	2	2	NUM
fnp-2845	3	5	,	,	PUNCT
fnp-2845	3	6	danielle	danielle	PROPN
fnp-2845	3	7	suzanne	suzanne	PROPN
fnp-2845	3	8	davies	davy	NOUN
fnp-2845	3	9	1	1	NUM
fnp-2845	3	10	,	,	PUNCT
fnp-2845	3	11	greg	greg	PROPN
fnp-2845	3	12	trevor	trevor	PROPN
fnp-2845	3	13	sutherland	sutherland	PROPN
fnp-2845	3	14	2	2	NUM
fnp-2845	3	15	,	,	PUNCT
fnp-2845	3	16	claire	claire	NOUN
fnp-2845	3	17	goldsbury	goldsbury	NOUN
fnp-2845	3	18	1	1	NUM
fnp-2845	3	19	1	1	NUM
fnp-2845	3	20	discipline	discipline	NOUN
fnp-2845	3	21	of	of	ADP
fnp-2845	3	22	anatomy	anatomy	NOUN
fnp-2845	3	23	and	and	CCONJ
fnp-2845	3	24	histology	histology	NOUN
fnp-2845	3	25	,	,	PUNCT
fnp-2845	3	26	school	school	NOUN
fnp-2845	3	27	of	of	ADP
fnp-2845	3	28	medical	medical	ADJ
fnp-2845	3	29	sciences	science	NOUN
fnp-2845	3	30	,	,	PUNCT
fnp-2845	3	31	faculty	faculty	NOUN
fnp-2845	3	32	of	of	ADP
fnp-2845	3	33	medicine	medicine	NOUN
fnp-2845	3	34	and	and	CCONJ
fnp-2845	3	35	health	health	NOUN
fnp-2845	3	36	,	,	PUNCT
fnp-2845	3	37	the	the	DET
fnp-2845	3	38	university	university	PROPN
fnp-2845	3	39	of	of	ADP
fnp-2845	3	40	sydney	sydney	PROPN
fnp-2845	3	41	,	,	PUNCT
fnp-2845	3	42	nsw	nsw	PROPN
fnp-2845	3	43	2006	2006	NUM
fnp-2845	3	44	,	,	PUNCT
fnp-2845	3	45	australia	australia	PROPN
fnp-2845	3	46	2	2	NUM
fnp-2845	3	47	discipline	discipline	NOUN
fnp-2845	3	48	of	of	ADP
fnp-2845	3	49	pathology	pathology	NOUN
fnp-2845	3	50	,	,	PUNCT
fnp-2845	3	51	school	school	NOUN
fnp-2845	3	52	of	of	ADP
fnp-2845	3	53	medical	medical	ADJ
fnp-2845	3	54	sciences	science	NOUN
fnp-2845	3	55	,	,	PUNCT
fnp-2845	3	56	faculty	faculty	NOUN
fnp-2845	3	57	of	of	ADP
fnp-2845	3	58	medicine	medicine	NOUN
fnp-2845	3	59	and	and	CCONJ
fnp-2845	3	60	health	health	NOUN
fnp-2845	3	61	,	,	PUNCT
fnp-2845	3	62	the	the	DET
fnp-2845	3	63	university	university	PROPN
fnp-2845	3	64	of	of	ADP
fnp-2845	3	65	sydney	sydney	PROPN
fnp-2845	3	66	,	,	PUNCT
fnp-2845	3	67	nsw	nsw	PROPN
fnp-2845	3	68	2006	2006	NUM
fnp-2845	3	69	,	,	PUNCT
fnp-2845	3	70	australia	australia	PROPN
fnp-2845	3	71	corresponding	corresponding	ADJ
fnp-2845	3	72	author	author	NOUN
fnp-2845	3	73	:	:	PUNCT
fnp-2845	3	74	dr	dr	PROPN
fnp-2845	3	75	claire	claire	PROPN
fnp-2845	3	76	goldsbury	goldsbury	PROPN
fnp-2845	3	77	phd	phd	NOUN
fnp-2845	3	78	·	·	PUNCT
fnp-2845	3	79	brain	brain	NOUN
fnp-2845	3	80	and	and	CCONJ
fnp-2845	3	81	mind	mind	NOUN
fnp-2845	3	82	centre	centre	PROPN
fnp-2845	3	83	·	·	PUNCT
fnp-2845	3	84	94	94	NUM
fnp-2845	3	85	mallett	mallett	PROPN
fnp-2845	3	86	street	street	PROPN
fnp-2845	3	87	·	·	PUNCT
fnp-2845	3	88	camperdown	camperdown	PROPN
fnp-2845	3	89	,	,	PUNCT
fnp-2845	3	90	nsw	nsw	PROPN
fnp-2845	3	91	2050	2050	NUM
fnp-2845	3	92	·	·	PUNCT
fnp-2845	4	1	australia	australia	PROPN
fnp-2845	4	2	·	·	PUNCT
fnp-2845	4	3	tel	tel	PROPN
fnp-2845	4	4	+61	+61	NOUN
fnp-2845	4	5	2	2	NUM
fnp-2845	4	6	9351	9351	NUM
fnp-2845	4	7	0878	0878	NUM
fnp-2845	4	8	claire.goldsbury@sydney.edu.au	claire.goldsbury@sydney.edu.au	PROPN
fnp-2845	4	9	submitted	submit	VERB
fnp-2845	4	10	:	:	PUNCT
fnp-2845	4	11	16	16	NUM
fnp-2845	4	12	june	june	PROPN
fnp-2845	4	13	2020	2020	NUM
fnp-2845	4	14	accepted	accept	VERB
fnp-2845	4	15	:	:	PUNCT
fnp-2845	4	16	29	29	NUM
fnp-2845	4	17	july	july	PROPN
fnp-2845	4	18	2020	2020	NUM
fnp-2845	4	19	copyedited	copyedit	VERB
fnp-2845	4	20	by	by	ADP
fnp-2845	4	21	:	:	PUNCT
fnp-2845	4	22	jeffrey	jeffrey	PROPN
fnp-2845	4	23	nirschl	nirschl	PROPN
fnp-2845	4	24	published	publish	VERB
fnp-2845	4	25	:	:	PUNCT
fnp-2845	5	1	04	04	NUM
fnp-2845	5	2	august	august	PROPN
fnp-2845	5	3	2020	2020	NUM
fnp-2845	5	4	https://doi.org/10.17879/freeneuropathology-2020-2845	https://doi.org/10.17879/freeneuropathology-2020-2845	PROPN
fnp-2845	5	5	keywords	keyword	NOUN
fnp-2845	5	6	:	:	PUNCT
fnp-2845	5	7	alzheimer	alzheimer	PROPN
fnp-2845	5	8	’s	’s	PART
fnp-2845	5	9	disease	disease	NOUN
fnp-2845	5	10	,	,	PUNCT
fnp-2845	5	11	inferior	inferior	ADJ
fnp-2845	5	12	temporal	temporal	ADJ
fnp-2845	5	13	cortex	cortex	NOUN
fnp-2845	5	14	,	,	PUNCT
fnp-2845	5	15	microglia	microglia	ADJ
fnp-2845	5	16	,	,	PUNCT
fnp-2845	5	17	post	post	ADJ
fnp-2845	5	18	-	-	ADJ
fnp-2845	5	19	mortem	mortem	ADJ
fnp-2845	5	20	human	human	ADJ
fnp-2845	5	21	brain	brain	NOUN
fnp-2845	5	22	tissue	tissue	NOUN
fnp-2845	5	23	,	,	PUNCT
fnp-2845	5	24	primary	primary	ADJ
fnp-2845	5	25	motor	motor	NOUN
fnp-2845	5	26	cortex	cortex	PROPN
fnp-2845	5	27	abstract	abstract	PROPN
fnp-2845	5	28	alzheimer	alzheimer	PROPN
fnp-2845	5	29	’s	’s	PART
fnp-2845	5	30	disease	disease	NOUN
fnp-2845	5	31	(	(	PUNCT
fnp-2845	5	32	ad	ad	NOUN
fnp-2845	5	33	)	)	PUNCT
fnp-2845	5	34	is	be	AUX
fnp-2845	5	35	a	a	DET
fnp-2845	5	36	late	late	ADJ
fnp-2845	5	37	-	-	PUNCT
fnp-2845	5	38	onset	onset	NOUN
fnp-2845	5	39	disease	disease	NOUN
fnp-2845	5	40	that	that	PRON
fnp-2845	5	41	has	have	AUX
fnp-2845	5	42	proved	prove	VERB
fnp-2845	5	43	difficult	difficult	ADJ
fnp-2845	5	44	to	to	PART
fnp-2845	5	45	model	model	VERB
fnp-2845	5	46	.	.	PUNCT
fnp-2845	6	1	microglia	microglia	NOUN
fnp-2845	6	2	are	be	AUX
fnp-2845	6	3	implicated	implicate	VERB
fnp-2845	6	4	in	in	ADP
fnp-2845	6	5	ad	ad	NOUN
fnp-2845	6	6	,	,	PUNCT
fnp-2845	6	7	but	but	CCONJ
fnp-2845	6	8	reports	report	NOUN
fnp-2845	6	9	vary	vary	VERB
fnp-2845	6	10	on	on	ADP
fnp-2845	6	11	precisely	precisely	ADV
fnp-2845	6	12	when	when	SCONJ
fnp-2845	6	13	and	and	CCONJ
fnp-2845	6	14	how	how	SCONJ
fnp-2845	6	15	in	in	ADP
fnp-2845	6	16	the	the	DET
fnp-2845	6	17	sequence	sequence	NOUN
fnp-2845	6	18	of	of	ADP
fnp-2845	6	19	pathological	pathological	ADJ
fnp-2845	6	20	changes	change	NOUN
fnp-2845	6	21	they	they	PRON
fnp-2845	6	22	become	become	VERB
fnp-2845	6	23	involved	involve	VERB
fnp-2845	6	24	.	.	PUNCT
fnp-2845	7	1	here	here	ADV
fnp-2845	7	2	,	,	PUNCT
fnp-2845	7	3	post	post	ADJ
fnp-2845	7	4	-	-	ADJ
fnp-2845	7	5	mortem	mortem	ADJ
fnp-2845	7	6	human	human	ADJ
fnp-2845	7	7	tissue	tissue	NOUN
fnp-2845	7	8	from	from	ADP
fnp-2845	7	9	two	two	NUM
fnp-2845	7	10	differentially	differentially	ADV
fnp-2845	7	11	affected	affect	VERB
fnp-2845	7	12	regions	region	NOUN
fnp-2845	7	13	of	of	ADP
fnp-2845	7	14	the	the	DET
fnp-2845	7	15	ad	ad	NOUN
fnp-2845	7	16	brain	brain	NOUN
fnp-2845	7	17	and	and	CCONJ
fnp-2845	7	18	from	from	ADP
fnp-2845	7	19	non	non	ADJ
fnp-2845	7	20	-	-	ADJ
fnp-2845	7	21	demented	demented	ADJ
fnp-2845	7	22	individuals	individual	NOUN
fnp-2845	7	23	with	with	ADP
fnp-2845	7	24	a	a	DET
fnp-2845	7	25	high	high	ADJ
fnp-2845	7	26	load	load	NOUN
fnp-2845	7	27	of	of	ADP
fnp-2845	7	28	ad	ad	NOUN
fnp-2845	7	29	-	-	PUNCT
fnp-2845	7	30	type	type	NOUN
fnp-2845	7	31	pathology	pathology	NOUN
fnp-2845	7	32	(	(	PUNCT
fnp-2845	7	33	high	high	ADJ
fnp-2845	7	34	pathology	pathology	NOUN
fnp-2845	7	35	controls	control	NOUN
fnp-2845	7	36	)	)	PUNCT
fnp-2845	7	37	was	be	AUX
fnp-2845	7	38	used	use	VERB
fnp-2845	7	39	to	to	PART
fnp-2845	7	40	model	model	VERB
fnp-2845	7	41	the	the	DET
fnp-2845	7	42	disease	disease	NOUN
fnp-2845	7	43	time	time	NOUN
fnp-2845	7	44	course	course	NOUN
fnp-2845	7	45	in	in	ADP
fnp-2845	7	46	order	order	NOUN
fnp-2845	7	47	to	to	PART
fnp-2845	7	48	determine	determine	VERB
fnp-2845	7	49	how	how	SCONJ
fnp-2845	7	50	microglial	microglial	ADJ
fnp-2845	7	51	activation	activation	NOUN
fnp-2845	7	52	relates	relate	VERB
fnp-2845	7	53	temporally	temporally	ADV
fnp-2845	7	54	to	to	ADP
fnp-2845	7	55	the	the	DET
fnp-2845	7	56	deposition	deposition	NOUN
fnp-2845	7	57	of	of	ADP
fnp-2845	7	58	hallmark	hallmark	ADJ
fnp-2845	7	59	amyloid	amyloid	NOUN
fnp-2845	7	60	-	-	PUNCT
fnp-2845	7	61	β	β	X
fnp-2845	7	62	(	(	PUNCT
fnp-2845	7	63	aβ	aβ	NOUN
fnp-2845	7	64	)	)	PUNCT
fnp-2845	7	65	and	and	CCONJ
fnp-2845	7	66	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-2845	7	67	microtubule	microtubule	NOUN
fnp-2845	7	68	associated	associate	VERB
fnp-2845	7	69	protein	protein	NOUN
fnp-2845	7	70	tau	tau	PROPN
fnp-2845	7	71	pathology	pathology	NOUN
fnp-2845	7	72	.	.	PUNCT
fnp-2845	8	1	immunofluorescence	immunofluorescence	NOUN
fnp-2845	8	2	against	against	ADP
fnp-2845	8	3	the	the	DET
fnp-2845	8	4	pan	pan	ADJ
fnp-2845	8	5	-	-	ADJ
fnp-2845	8	6	microglial	microglial	ADJ
fnp-2845	8	7	marker	marker	NOUN
fnp-2845	8	8	,	,	PUNCT
fnp-2845	8	9	ionised	ionise	VERB
fnp-2845	8	10	calcium	calcium	NOUN
fnp-2845	8	11	-	-	PUNCT
fnp-2845	8	12	binding	bind	VERB
fnp-2845	8	13	adapter	adapter	NOUN
fnp-2845	8	14	molecule	molecule	NOUN
fnp-2845	8	15	1	1	NUM
fnp-2845	8	16	(	(	PUNCT
fnp-2845	8	17	iba1	iba1	PROPN
fnp-2845	8	18	)	)	PUNCT
fnp-2845	8	19	,	,	PUNCT
fnp-2845	8	20	aβ	aβ	NOUN
fnp-2845	8	21	and	and	CCONJ
fnp-2845	8	22	tau	tau	PROPN
fnp-2845	8	23	,	,	PUNCT
fnp-2845	8	24	was	be	AUX
fnp-2845	8	25	performed	perform	VERB
fnp-2845	8	26	in	in	ADP
fnp-2845	8	27	the	the	DET
fnp-2845	8	28	primary	primary	ADJ
fnp-2845	8	29	motor	motor	NOUN
fnp-2845	8	30	cortex	cortex	NOUN
fnp-2845	8	31	(	(	PUNCT
fnp-2845	8	32	pmc	pmc	PROPN
fnp-2845	8	33	)	)	PUNCT
fnp-2845	8	34	,	,	PUNCT
fnp-2845	8	35	a	a	DET
fnp-2845	8	36	region	region	NOUN
fnp-2845	8	37	relatively	relatively	ADV
fnp-2845	8	38	spared	spare	VERB
fnp-2845	8	39	of	of	ADP
fnp-2845	8	40	ad	ad	NOUN
fnp-2845	8	41	pathological	pathological	ADJ
fnp-2845	8	42	changes	change	NOUN
fnp-2845	8	43	,	,	PUNCT
fnp-2845	8	44	and	and	CCONJ
fnp-2845	8	45	compared	compare	VERB
fnp-2845	8	46	to	to	ADP
fnp-2845	8	47	the	the	DET
fnp-2845	8	48	severely	severely	ADV
fnp-2845	8	49	affected	affect	VERB
fnp-2845	8	50	inferior	inferior	ADJ
fnp-2845	8	51	temporal	temporal	ADJ
fnp-2845	8	52	cortex	cortex	NOUN
fnp-2845	8	53	(	(	PUNCT
fnp-2845	8	54	itc	itc	PROPN
fnp-2845	8	55	)	)	PUNCT
fnp-2845	8	56	in	in	ADP
fnp-2845	8	57	the	the	DET
fnp-2845	8	58	same	same	ADJ
fnp-2845	8	59	cases	case	NOUN
fnp-2845	8	60	.	.	PUNCT
fnp-2845	9	1	unlike	unlike	ADP
fnp-2845	9	2	the	the	DET
fnp-2845	9	3	itc	itc	PROPN
fnp-2845	9	4	,	,	PUNCT
fnp-2845	9	5	the	the	DET
fnp-2845	9	6	pmc	pmc	PROPN
fnp-2845	9	7	in	in	ADP
fnp-2845	9	8	the	the	DET
fnp-2845	9	9	ad	ad	NOUN
fnp-2845	9	10	cases	case	NOUN
fnp-2845	9	11	was	be	AUX
fnp-2845	9	12	spared	spare	VERB
fnp-2845	9	13	of	of	ADP
fnp-2845	9	14	any	any	DET
fnp-2845	9	15	degenerative	degenerative	ADJ
fnp-2845	9	16	changes	change	NOUN
fnp-2845	9	17	in	in	ADP
fnp-2845	9	18	cortical	cortical	ADJ
fnp-2845	9	19	thickness	thickness	NOUN
fnp-2845	9	20	and	and	CCONJ
fnp-2845	9	21	the	the	DET
fnp-2845	9	22	density	density	NOUN
fnp-2845	9	23	of	of	ADP
fnp-2845	9	24	betz	betz	PROPN
fnp-2845	9	25	cells	cell	NOUN
fnp-2845	9	26	and	and	CCONJ
fnp-2845	9	27	total	total	ADJ
fnp-2845	9	28	neurons	neuron	NOUN
fnp-2845	9	29	.	.	PUNCT
fnp-2845	10	1	the	the	DET
fnp-2845	10	2	clustering	clustering	NOUN
fnp-2845	10	3	of	of	ADP
fnp-2845	10	4	activated	activated	ADJ
fnp-2845	10	5	microglia	microglia	NOUN
fnp-2845	10	6	was	be	AUX
fnp-2845	10	7	greatest	great	ADJ
fnp-2845	10	8	in	in	ADP
fnp-2845	10	9	the	the	DET
fnp-2845	10	10	pmc	pmc	PROPN
fnp-2845	10	11	of	of	ADP
fnp-2845	10	12	ad	ad	NOUN
fnp-2845	10	13	cases	case	NOUN
fnp-2845	10	14	and	and	CCONJ
fnp-2845	10	15	high	high	ADJ
fnp-2845	10	16	pathology	pathology	NOUN
fnp-2845	10	17	controls	control	NOUN
fnp-2845	10	18	compared	compare	VERB
fnp-2845	10	19	to	to	ADP
fnp-2845	10	20	the	the	DET
fnp-2845	10	21	itc	itc	PROPN
fnp-2845	10	22	.	.	PUNCT
fnp-2845	11	1	this	this	PRON
fnp-2845	11	2	suggests	suggest	VERB
fnp-2845	11	3	microglial	microglial	ADJ
fnp-2845	11	4	activation	activation	NOUN
fnp-2845	11	5	is	be	AUX
fnp-2845	11	6	most	most	ADV
fnp-2845	11	7	prominent	prominent	ADJ
fnp-2845	11	8	in	in	ADP
fnp-2845	11	9	the	the	DET
fnp-2845	11	10	early	early	ADJ
fnp-2845	11	11	phases	phase	NOUN
fnp-2845	11	12	of	of	ADP
fnp-2845	11	13	ad	ad	NOUN
fnp-2845	11	14	pathophysiology	pathophysiology	NOUN
fnp-2845	11	15	.	.	PUNCT
fnp-2845	12	1	nascent	nascent	ADJ
fnp-2845	12	2	tau	tau	PROPN
fnp-2845	12	3	inclusions	inclusion	NOUN
fnp-2845	12	4	were	be	AUX
fnp-2845	12	5	found	find	VERB
fnp-2845	12	6	in	in	ADP
fnp-2845	12	7	neuritic	neuritic	ADJ
fnp-2845	12	8	plaques	plaque	NOUN
fnp-2845	12	9	in	in	ADP
fnp-2845	12	10	the	the	DET
fnp-2845	12	11	pmc	pmc	NOUN
fnp-2845	12	12	but	but	CCONJ
fnp-2845	12	13	were	be	AUX
fnp-2845	12	14	more	more	ADV
fnp-2845	12	15	numerous	numerous	ADJ
fnp-2845	12	16	in	in	ADP
fnp-2845	12	17	the	the	DET
fnp-2845	12	18	itc	itc	NOUN
fnp-2845	12	19	of	of	ADP
fnp-2845	12	20	the	the	DET
fnp-2845	12	21	same	same	ADJ
fnp-2845	12	22	case	case	NOUN
fnp-2845	12	23	.	.	PUNCT
fnp-2845	13	1	this	this	PRON
fnp-2845	13	2	shows	show	VERB
fnp-2845	13	3	that	that	SCONJ
fnp-2845	13	4	tau	tau	PROPN
fnp-2845	13	5	positive	positive	ADJ
fnp-2845	13	6	neuritic	neuritic	ADJ
fnp-2845	13	7	plaques	plaque	NOUN
fnp-2845	13	8	begin	begin	VERB
fnp-2845	13	9	early	early	ADV
fnp-2845	13	10	in	in	ADP
fnp-2845	13	11	ad	ad	NOUN
fnp-2845	13	12	which	which	PRON
fnp-2845	13	13	is	be	AUX
fnp-2845	13	14	likely	likely	ADJ
fnp-2845	13	15	of	of	ADP
fnp-2845	13	16	pathogenic	pathogenic	ADJ
fnp-2845	13	17	importance	importance	NOUN
fnp-2845	13	18	,	,	PUNCT
fnp-2845	13	19	however	however	ADV
fnp-2845	13	20	major	major	ADJ
fnp-2845	13	21	tau	tau	PROPN
fnp-2845	13	22	deposition	deposition	NOUN
fnp-2845	13	23	follows	follow	VERB
fnp-2845	13	24	the	the	DET
fnp-2845	13	25	accumulation	accumulation	NOUN
fnp-2845	13	26	of	of	ADP
fnp-2845	13	27	aβ	aβ	NOUN
fnp-2845	13	28	and	and	CCONJ
fnp-2845	13	29	clustering	clustering	NOUN
fnp-2845	13	30	of	of	ADP
fnp-2845	13	31	activated	activated	ADJ
fnp-2845	13	32	microglia	microglia	NOUN
fnp-2845	13	33	.	.	PUNCT
fnp-2845	14	1	importantly	importantly	ADV
fnp-2845	14	2	,	,	PUNCT
fnp-2845	14	3	findings	finding	NOUN
fnp-2845	14	4	presented	present	VERB
fnp-2845	14	5	here	here	ADV
fnp-2845	14	6	demonstrate	demonstrate	VERB
fnp-2845	14	7	that	that	SCONJ
fnp-2845	14	8	different	different	ADJ
fnp-2845	14	9	states	state	NOUN
fnp-2845	14	10	of	of	ADP
fnp-2845	14	11	microglial	microglial	ADJ
fnp-2845	14	12	activation	activation	NOUN
fnp-2845	14	13	,	,	PUNCT
fnp-2845	14	14	corresponding	correspond	VERB
fnp-2845	14	15	to	to	ADP
fnp-2845	14	16	regional	regional	ADJ
fnp-2845	14	17	accumulations	accumulation	NOUN
fnp-2845	14	18	of	of	ADP
fnp-2845	14	19	aβ	aβ	PRON
fnp-2845	14	20	and	and	CCONJ
fnp-2845	14	21	tau	tau	PROPN
fnp-2845	14	22	,	,	PUNCT
fnp-2845	14	23	are	be	AUX
fnp-2845	14	24	present	present	ADJ
fnp-2845	14	25	simultaneously	simultaneously	ADV
fnp-2845	14	26	in	in	ADP
fnp-2845	14	27	the	the	DET
fnp-2845	14	28	same	same	ADJ
fnp-2845	14	29	individual	individual	NOUN
fnp-2845	14	30	;	;	PUNCT
fnp-2845	14	31	an	an	DET
fnp-2845	14	32	important	important	ADJ
fnp-2845	14	33	factor	factor	NOUN
fnp-2845	14	34	for	for	ADP
fnp-2845	14	35	consideration	consideration	NOUN
fnp-2845	14	36	if	if	SCONJ
fnp-2845	14	37	targeting	target	VERB
fnp-2845	14	38	these	these	DET
fnp-2845	14	39	cells	cell	NOUN
fnp-2845	14	40	for	for	ADP
fnp-2845	14	41	therapeutic	therapeutic	ADJ
fnp-2845	14	42	intervention	intervention	NOUN
fnp-2845	14	43	.	.	PUNCT
fnp-2845	15	1	introduction	introduction	NOUN
fnp-2845	15	2	alzheimer	alzheimer	PROPN
fnp-2845	15	3	’s	’s	PART
fnp-2845	15	4	disease	disease	NOUN
fnp-2845	15	5	(	(	PUNCT
fnp-2845	15	6	ad	ad	NOUN
fnp-2845	15	7	)	)	PUNCT
fnp-2845	15	8	is	be	AUX
fnp-2845	15	9	neuropathologically	neuropathologically	ADV
fnp-2845	15	10	characterised	characterise	VERB
fnp-2845	15	11	by	by	ADP
fnp-2845	15	12	inclusions	inclusion	NOUN
fnp-2845	15	13	of	of	ADP
fnp-2845	15	14	microtubule	microtubule	NOUN
fnp-2845	15	15	-	-	PUNCT
fnp-2845	15	16	associated	associate	VERB
fnp-2845	15	17	protein	protein	NOUN
fnp-2845	15	18	tau	tau	PROPN
fnp-2845	15	19	(	(	PUNCT
fnp-2845	15	20	tau	tau	PROPN
fnp-2845	15	21	)	)	PUNCT
fnp-2845	15	22	and	and	CCONJ
fnp-2845	15	23	extracellular	extracellular	ADJ
fnp-2845	15	24	deposits	deposit	NOUN
fnp-2845	15	25	of	of	ADP
fnp-2845	15	26	β	β	NOUN
fnp-2845	15	27	-	-	NOUN
fnp-2845	15	28	amyloid	amyloid	NOUN
fnp-2845	15	29	(	(	PUNCT
fnp-2845	15	30	aβ	aβ	NOUN
fnp-2845	15	31	)	)	PUNCT
fnp-2845	15	32	.	.	PUNCT
fnp-2845	16	1	intraneuronal	intraneuronal	PROPN
fnp-2845	16	2	tau	tau	PROPN
fnp-2845	16	3	pathology	pathology	NOUN
fnp-2845	16	4	includes	include	VERB
fnp-2845	16	5	neurofibrillary	neurofibrillary	ADJ
fnp-2845	16	6	tangles	tangle	NOUN
fnp-2845	16	7	(	(	PUNCT
fnp-2845	16	8	nfts	nft	NOUN
fnp-2845	16	9	)	)	PUNCT
fnp-2845	16	10	in	in	ADP
fnp-2845	16	11	the	the	DET
fnp-2845	16	12	cell	cell	NOUN
fnp-2845	16	13	soma	soma	NOUN
fnp-2845	16	14	and	and	CCONJ
fnp-2845	16	15	neuropil	neuropil	NOUN
fnp-2845	16	16	threads	thread	NOUN
fnp-2845	16	17	(	(	PUNCT
fnp-2845	16	18	nts	nt	NOUN
fnp-2845	16	19	)	)	PUNCT
fnp-2845	16	20	,	,	PUNCT
fnp-2845	16	21	which	which	PRON
fnp-2845	16	22	occur	occur	VERB
fnp-2845	16	23	mostly	mostly	ADV
fnp-2845	16	24	in	in	ADP
fnp-2845	16	25	the	the	DET
fnp-2845	16	26	dendritic	dendritic	ADJ
fnp-2845	16	27	compartment	compartment	NOUN
fnp-2845	16	28	,	,	PUNCT
fnp-2845	16	29	but	but	CCONJ
fnp-2845	16	30	also	also	ADV
fnp-2845	16	31	in	in	ADP
fnp-2845	16	32	the	the	DET
fnp-2845	16	33	axonal	axonal	ADJ
fnp-2845	16	34	domain	domain	NOUN
fnp-2845	16	35	though	though	SCONJ
fnp-2845	16	36	to	to	ADP
fnp-2845	16	37	a	a	DET
fnp-2845	16	38	lesser	less	ADJ
fnp-2845	16	39	extent	extent	NOUN
fnp-2845	16	40	(	(	PUNCT
fnp-2845	16	41	1	1	NUM
fnp-2845	16	42	,	,	PUNCT
fnp-2845	16	43	2	2	NUM
fnp-2845	16	44	)	)	PUNCT
fnp-2845	16	45	.	.	PUNCT
fnp-2845	17	1	nfts	nft	NOUN
fnp-2845	17	2	and	and	CCONJ
fnp-2845	17	3	nts	nt	NOUN
fnp-2845	17	4	are	be	AUX
fnp-2845	17	5	both	both	PRON
fnp-2845	17	6	comprised	comprise	VERB
fnp-2845	17	7	of	of	ADP
fnp-2845	17	8	paired	pair	VERB
fnp-2845	17	9	helical	helical	ADJ
fnp-2845	17	10	filaments	filament	NOUN
fnp-2845	17	11	and	and	CCONJ
fnp-2845	17	12	straight	straight	ADJ
fnp-2845	17	13	filaments	filament	NOUN
fnp-2845	17	14	of	of	ADP
fnp-2845	17	15	polymerised	polymerise	VERB
fnp-2845	17	16	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-2845	17	17	tau	tau	PROPN
fnp-2845	17	18	protein	protein	NOUN
fnp-2845	17	19	(	(	PUNCT
fnp-2845	17	20	3	3	NUM
fnp-2845	17	21	,	,	PUNCT
fnp-2845	17	22	4	4	NUM
fnp-2845	17	23	)	)	PUNCT
fnp-2845	17	24	.	.	PUNCT
fnp-2845	18	1	the	the	DET
fnp-2845	18	2	extent	extent	NOUN
fnp-2845	18	3	of	of	ADP
fnp-2845	18	4	tau	tau	PROPN
fnp-2845	18	5	pathology	pathology	NOUN
fnp-2845	18	6	follows	follow	VERB
fnp-2845	18	7	a	a	DET
fnp-2845	18	8	predictable	predictable	ADJ
fnp-2845	18	9	spatiotemporal	spatiotemporal	ADJ
fnp-2845	18	10	progression	progression	NOUN
fnp-2845	18	11	through	through	ADP
fnp-2845	18	12	functionally	functionally	ADV
fnp-2845	18	13	integrated	integrate	VERB
fnp-2845	18	14	brain	brain	NOUN
fnp-2845	18	15	regions	region	NOUN
fnp-2845	18	16	(	(	PUNCT
fnp-2845	18	17	5	5	NUM
fnp-2845	18	18	,	,	PUNCT
fnp-2845	18	19	6	6	NUM
fnp-2845	18	20	)	)	PUNCT
fnp-2845	18	21	and	and	CCONJ
fnp-2845	18	22	there	there	PRON
fnp-2845	18	23	is	be	VERB
fnp-2845	18	24	an	an	DET
fnp-2845	18	25	extensive	extensive	ADJ
fnp-2845	18	26	body	body	NOUN
fnp-2845	18	27	of	of	ADP
fnp-2845	18	28	literature	literature	NOUN
fnp-2845	18	29	that	that	PRON
fnp-2845	18	30	demonstrates	demonstrate	VERB
fnp-2845	18	31	an	an	DET
fnp-2845	18	32	inverse	inverse	NOUN
fnp-2845	18	33	correlation	correlation	NOUN
fnp-2845	18	34	between	between	ADP
fnp-2845	18	35	the	the	DET
fnp-2845	18	36	accumulation	accumulation	NOUN
fnp-2845	18	37	of	of	ADP
fnp-2845	18	38	nfts	nft	NOUN
fnp-2845	18	39	and	and	CCONJ
fnp-2845	18	40	cognitive	cognitive	ADJ
fnp-2845	18	41	status	status	NOUN
fnp-2845	18	42	(	(	PUNCT
fnp-2845	18	43	7	7	NUM
fnp-2845	18	44	)	)	PUNCT
fnp-2845	18	45	such	such	ADJ
fnp-2845	18	46	that	that	SCONJ
fnp-2845	18	47	the	the	DET
fnp-2845	18	48	spread	spread	NOUN
fnp-2845	18	49	and	and	CCONJ
fnp-2845	18	50	regional	regional	ADJ
fnp-2845	18	51	level	level	NOUN
fnp-2845	18	52	of	of	ADP
fnp-2845	18	53	nfts	nft	NOUN
fnp-2845	18	54	reflects	reflect	VERB
fnp-2845	18	55	the	the	DET
fnp-2845	18	56	severity	severity	NOUN
fnp-2845	18	57	of	of	ADP
fnp-2845	18	58	dementia	dementia	NOUN
fnp-2845	18	59	with	with	ADP
fnp-2845	18	60	time	time	NOUN
fnp-2845	18	61	(	(	PUNCT
fnp-2845	18	62	8)	8)	NUM
fnp-2845	18	63	.	.	NOUN
fnp-2845	18	64	contrastingly	contrastingly	ADV
fnp-2845	18	65	,	,	PUNCT
fnp-2845	18	66	aβ	aβ	DET
fnp-2845	18	67	plaques	plaque	NOUN
fnp-2845	18	68	follow	follow	VERB
fnp-2845	18	69	a	a	DET
fnp-2845	18	70	seemingly	seemingly	ADV
fnp-2845	18	71	more	more	ADV
fnp-2845	18	72	haphazard	haphazard	ADJ
fnp-2845	18	73	regional	regional	ADJ
fnp-2845	18	74	pattern	pattern	NOUN
fnp-2845	18	75	of	of	ADP
fnp-2845	18	76	accumulation	accumulation	NOUN
fnp-2845	18	77	throughout	throughout	ADP
fnp-2845	18	78	the	the	DET
fnp-2845	18	79	neocortex	neocortex	NOUN
fnp-2845	18	80	,	,	PUNCT
fnp-2845	18	81	indeed	indeed	ADV
fnp-2845	18	82	plateauing	plateaue	VERB
fnp-2845	18	83	relatively	relatively	ADV
fnp-2845	18	84	early	early	ADV
fnp-2845	18	85	in	in	ADP
fnp-2845	18	86	the	the	DET
fnp-2845	18	87	disease	disease	NOUN
fnp-2845	18	88	time	time	NOUN
fnp-2845	18	89	course	course	NOUN
fnp-2845	18	90	(	(	PUNCT
fnp-2845	18	91	9	9	NUM
fnp-2845	18	92	,	,	PUNCT
fnp-2845	18	93	10	10	NUM
fnp-2845	18	94	)	)	PUNCT
fnp-2845	18	95	,	,	PUNCT
fnp-2845	18	96	and	and	CCONJ
fnp-2845	18	97	therefore	therefore	ADV
fnp-2845	18	98	correlate	correlate	VERB
fnp-2845	18	99	poorly	poorly	ADV
fnp-2845	18	100	with	with	ADP
fnp-2845	18	101	disease	disease	NOUN
fnp-2845	18	102	status	status	NOUN
fnp-2845	18	103	until	until	SCONJ
fnp-2845	18	104	substantial	substantial	ADJ
fnp-2845	18	105	argyrophilic	argyrophilic	ADJ
fnp-2845	18	106	neuritic	neuritic	PROPN
fnp-2845	18	107	tau	tau	PROPN
fnp-2845	18	108	pathology	pathology	NOUN
fnp-2845	18	109	is	be	AUX
fnp-2845	18	110	also	also	ADV
fnp-2845	18	111	present	present	ADJ
fnp-2845	18	112	(	(	PUNCT
fnp-2845	18	113	5	5	NUM
fnp-2845	18	114	,	,	PUNCT
fnp-2845	18	115	7	7	NUM
fnp-2845	18	116	,	,	PUNCT
fnp-2845	18	117	11	11	NUM
fnp-2845	18	118	)	)	PUNCT
fnp-2845	18	119	.	.	PUNCT
fnp-2845	19	1	whilst	whilst	SCONJ
fnp-2845	19	2	aβ	aβ	DET
fnp-2845	19	3	load	load	NOUN
fnp-2845	19	4	may	may	AUX
fnp-2845	19	5	be	be	AUX
fnp-2845	19	6	an	an	DET
fnp-2845	19	7	unreliable	unreliable	ADJ
fnp-2845	19	8	indicator	indicator	NOUN
fnp-2845	19	9	of	of	ADP
fnp-2845	19	10	disease	disease	NOUN
fnp-2845	19	11	severity	severity	NOUN
fnp-2845	19	12	,	,	PUNCT
fnp-2845	19	13	it	it	PRON
fnp-2845	19	14	is	be	AUX
fnp-2845	19	15	generally	generally	ADV
fnp-2845	19	16	accepted	accept	VERB
fnp-2845	19	17	that	that	SCONJ
fnp-2845	19	18	the	the	DET
fnp-2845	19	19	extent	extent	NOUN
fnp-2845	19	20	of	of	ADP
fnp-2845	19	21	its	its	PRON
fnp-2845	19	22	spread	spread	NOUN
fnp-2845	19	23	,	,	PUNCT
fnp-2845	19	24	in	in	ADP
fnp-2845	19	25	combination	combination	NOUN
fnp-2845	19	26	with	with	ADP
fnp-2845	19	27	tau	tau	PROPN
fnp-2845	19	28	pathology	pathology	NOUN
fnp-2845	19	29	,	,	PUNCT
fnp-2845	19	30	is	be	AUX
fnp-2845	19	31	useful	useful	ADJ
fnp-2845	19	32	for	for	ADP
fnp-2845	19	33	staging	stage	VERB
fnp-2845	19	34	purposes	purpose	NOUN
fnp-2845	19	35	(	(	PUNCT
fnp-2845	19	36	9	9	NUM
fnp-2845	19	37	)	)	PUNCT
fnp-2845	19	38	.	.	PUNCT
fnp-2845	20	1	aβ	aβ	PRON
fnp-2845	20	2	plaques	plaque	NOUN
fnp-2845	20	3	can	can	AUX
fnp-2845	20	4	be	be	AUX
fnp-2845	20	5	classified	classify	VERB
fnp-2845	20	6	with	with	ADP
fnp-2845	20	7	immunostaining	immunostaine	VERB
fnp-2845	20	8	into	into	ADP
fnp-2845	20	9	at	at	ADV
fnp-2845	20	10	least	least	ADV
fnp-2845	20	11	three	three	NUM
fnp-2845	20	12	morphologically	morphologically	ADV
fnp-2845	20	13	distinct	distinct	ADJ
fnp-2845	20	14	categories	category	NOUN
fnp-2845	20	15	:	:	PUNCT
fnp-2845	20	16	diffuse	diffuse	ADJ
fnp-2845	20	17	,	,	PUNCT
fnp-2845	20	18	fibrillar	fibrillar	ADJ
fnp-2845	20	19	,	,	PUNCT
fnp-2845	20	20	or	or	CCONJ
fnp-2845	20	21	dense	dense	ADV
fnp-2845	20	22	-	-	PUNCT
fnp-2845	20	23	cored	core	VERB
fnp-2845	20	24	.	.	PUNCT
fnp-2845	21	1	diffuse	diffuse	ADJ
fnp-2845	21	2	plaques	plaque	NOUN
fnp-2845	21	3	have	have	AUX
fnp-2845	21	4	long	long	ADV
fnp-2845	21	5	been	be	AUX
fnp-2845	21	6	proposed	propose	VERB
fnp-2845	21	7	to	to	PART
fnp-2845	21	8	be	be	AUX
fnp-2845	21	9	a	a	DET
fnp-2845	21	10	structural	structural	ADJ
fnp-2845	21	11	precursor	precursor	NOUN
fnp-2845	21	12	of	of	ADP
fnp-2845	21	13	other	other	ADJ
fnp-2845	21	14	plaque	plaque	NOUN
fnp-2845	21	15	forms	form	NOUN
fnp-2845	21	16	,	,	PUNCT
fnp-2845	21	17	but	but	CCONJ
fnp-2845	21	18	whether	whether	SCONJ
fnp-2845	21	19	these	these	DET
fnp-2845	21	20	categories	category	NOUN
fnp-2845	21	21	represent	represent	VERB
fnp-2845	21	22	separate	separate	ADJ
fnp-2845	21	23	entities	entity	NOUN
fnp-2845	21	24	with	with	ADP
fnp-2845	21	25	independent	independent	ADJ
fnp-2845	21	26	mechanisms	mechanism	NOUN
fnp-2845	21	27	of	of	ADP
fnp-2845	21	28	development	development	NOUN
fnp-2845	21	29	or	or	CCONJ
fnp-2845	21	30	are	be	AUX
fnp-2845	21	31	temporally	temporally	ADV
fnp-2845	21	32	linked	link	VERB
fnp-2845	21	33	is	be	AUX
fnp-2845	21	34	still	still	ADV
fnp-2845	21	35	unclear	unclear	ADJ
fnp-2845	21	36	.	.	PUNCT
fnp-2845	22	1	neuritic	neuritic	ADJ
fnp-2845	22	2	plaques	plaque	NOUN
fnp-2845	22	3	(	(	PUNCT
fnp-2845	22	4	nps	nps	PROPN
fnp-2845	22	5	)	)	PUNCT
fnp-2845	22	6	are	be	AUX
fnp-2845	22	7	those	those	DET
fnp-2845	22	8	aβ	aβ	ADP
fnp-2845	22	9	plaques	plaque	NOUN
fnp-2845	22	10	that	that	PRON
fnp-2845	22	11	also	also	ADV
fnp-2845	22	12	feature	feature	VERB
fnp-2845	22	13	dystrophic	dystrophic	ADJ
fnp-2845	22	14	neurites	neurite	NOUN
fnp-2845	22	15	(	(	PUNCT
fnp-2845	22	16	dns	dns	NOUN
fnp-2845	22	17	)	)	PUNCT
fnp-2845	22	18	with	with	ADP
fnp-2845	22	19	silver	silver	NOUN
fnp-2845	22	20	staining	staining	NOUN
fnp-2845	22	21	.	.	PUNCT
fnp-2845	23	1	dns	dns	NOUN
fnp-2845	23	2	can	can	AUX
fnp-2845	23	3	occur	occur	VERB
fnp-2845	23	4	in	in	ADP
fnp-2845	23	5	all	all	DET
fnp-2845	23	6	these	these	DET
fnp-2845	23	7	morphological	morphological	ADJ
fnp-2845	23	8	subtypes	subtype	NOUN
fnp-2845	23	9	of	of	ADP
fnp-2845	23	10	aβ	aβ	DET
fnp-2845	23	11	plaques	plaque	NOUN
fnp-2845	23	12	,	,	PUNCT
fnp-2845	23	13	though	though	SCONJ
fnp-2845	23	14	more	more	ADV
fnp-2845	23	15	commonly	commonly	ADV
fnp-2845	23	16	in	in	ADP
fnp-2845	23	17	dense	dense	ADV
fnp-2845	23	18	-	-	PUNCT
fnp-2845	23	19	cored	core	VERB
fnp-2845	23	20	and	and	CCONJ
fnp-2845	23	21	fibrillar	fibrillar	ADJ
fnp-2845	23	22	plaques	plaque	NOUN
fnp-2845	23	23	than	than	ADP
fnp-2845	23	24	morphologically	morphologically	ADV
fnp-2845	23	25	diffuse	diffuse	ADJ
fnp-2845	23	26	plaques	plaque	NOUN
fnp-2845	23	27	(	(	PUNCT
fnp-2845	23	28	12	12	NUM
fnp-2845	23	29	)	)	PUNCT
fnp-2845	23	30	.	.	PUNCT
fnp-2845	24	1	most	most	ADJ
fnp-2845	24	2	dns	dns	NOUN
fnp-2845	24	3	are	be	AUX
fnp-2845	24	4	tau	tau	NOUN
fnp-2845	24	5	-	-	PUNCT
fnp-2845	24	6	positive	positive	ADJ
fnp-2845	24	7	and	and	CCONJ
fnp-2845	24	8	morphologically	morphologically	ADV
fnp-2845	24	9	similar	similar	ADJ
fnp-2845	24	10	to	to	ADP
fnp-2845	24	11	nts	nt	NOUN
fnp-2845	24	12	which	which	PRON
fnp-2845	24	13	are	be	AUX
fnp-2845	24	14	elongated	elongate	VERB
fnp-2845	24	15	in	in	ADP
fnp-2845	24	16	shape	shape	NOUN
fnp-2845	24	17	,	,	PUNCT
fnp-2845	24	18	but	but	CCONJ
fnp-2845	24	19	may	may	AUX
fnp-2845	24	20	also	also	ADV
fnp-2845	24	21	be	be	AUX
fnp-2845	24	22	globular	globular	ADJ
fnp-2845	24	23	,	,	PUNCT
fnp-2845	24	24	and	and	CCONJ
fnp-2845	24	25	possibly	possibly	ADV
fnp-2845	24	26	represent	represent	VERB
fnp-2845	24	27	swollen	swollen	ADJ
fnp-2845	24	28	presynaptic	presynaptic	ADJ
fnp-2845	24	29	(	(	PUNCT
fnp-2845	24	30	axonal	axonal	ADJ
fnp-2845	24	31	)	)	PUNCT
fnp-2845	24	32	terminals	terminal	NOUN
fnp-2845	24	33	(	(	PUNCT
fnp-2845	24	34	13	13	NUM
fnp-2845	24	35	)	)	PUNCT
fnp-2845	24	36	.	.	PUNCT
fnp-2845	25	1	nps	nps	PROPN
fnp-2845	25	2	that	that	PRON
fnp-2845	25	3	retain	retain	VERB
fnp-2845	25	4	sparse	sparse	ADJ
fnp-2845	25	5	dns	dns	NOUN
fnp-2845	25	6	but	but	CCONJ
fnp-2845	25	7	show	show	VERB
fnp-2845	25	8	minimal	minimal	ADJ
fnp-2845	25	9	aβ	aβ	NOUN
fnp-2845	25	10	staining	stain	VERB
fnp-2845	25	11	have	have	AUX
fnp-2845	25	12	previously	previously	ADV
fnp-2845	25	13	been	be	AUX
fnp-2845	25	14	described	describe	VERB
fnp-2845	25	15	and	and	CCONJ
fnp-2845	25	16	were	be	AUX
fnp-2845	25	17	termed	term	VERB
fnp-2845	25	18	‘	'	PUNCT
fnp-2845	25	19	remnant	remnant	ADJ
fnp-2845	25	20	plaques	plaque	NOUN
fnp-2845	25	21	’	'	PUNCT
fnp-2845	25	22	which	which	PRON
fnp-2845	25	23	were	be	AUX
fnp-2845	25	24	proposed	propose	VERB
fnp-2845	25	25	to	to	PART
fnp-2845	25	26	result	result	VERB
fnp-2845	25	27	from	from	ADP
fnp-2845	25	28	glial	glial	ADJ
fnp-2845	25	29	phagocytosis	phagocytosis	NOUN
fnp-2845	25	30	of	of	ADP
fnp-2845	25	31	insoluble	insoluble	ADJ
fnp-2845	25	32	aβ	aβ	INTJ
fnp-2845	25	33	(	(	PUNCT
fnp-2845	25	34	14	14	NUM
fnp-2845	25	35	)	)	PUNCT
fnp-2845	25	36	.	.	PUNCT
fnp-2845	26	1	there	there	PRON
fnp-2845	26	2	remains	remain	VERB
fnp-2845	26	3	significant	significant	ADJ
fnp-2845	26	4	debate	debate	NOUN
fnp-2845	26	5	as	as	ADP
fnp-2845	26	6	to	to	ADP
fnp-2845	26	7	the	the	DET
fnp-2845	26	8	sequence	sequence	NOUN
fnp-2845	26	9	of	of	ADP
fnp-2845	26	10	the	the	DET
fnp-2845	26	11	neuropathological	neuropathological	ADJ
fnp-2845	26	12	changes	change	NOUN
fnp-2845	26	13	that	that	PRON
fnp-2845	26	14	precede	precede	VERB
fnp-2845	26	15	the	the	DET
fnp-2845	26	16	onset	onset	NOUN
fnp-2845	26	17	of	of	ADP
fnp-2845	26	18	ad	ad	NOUN
fnp-2845	26	19	symptomatology	symptomatology	NOUN
fnp-2845	26	20	.	.	PUNCT
fnp-2845	27	1	the	the	DET
fnp-2845	27	2	amyloid	amyloid	NOUN
fnp-2845	27	3	cascade	cascade	NOUN
fnp-2845	27	4	hypothesis	hypothesis	NOUN
fnp-2845	27	5	posits	posit	NOUN
fnp-2845	27	6	aβ	aβ	VERB
fnp-2845	27	7	,	,	PUNCT
fnp-2845	27	8	and	and	CCONJ
fnp-2845	27	9	in	in	ADP
fnp-2845	27	10	particular	particular	ADJ
fnp-2845	27	11	the	the	DET
fnp-2845	27	12	soluble	soluble	ADJ
fnp-2845	27	13	,	,	PUNCT
fnp-2845	27	14	oligomeric	oligomeric	ADJ
fnp-2845	27	15	,	,	PUNCT
fnp-2845	27	16	non	non	ADJ
fnp-2845	27	17	-	-	ADJ
fnp-2845	27	18	fibrillar	fibrillar	ADJ
fnp-2845	27	19	fraction	fraction	NOUN
fnp-2845	27	20	,	,	PUNCT
fnp-2845	27	21	as	as	ADP
fnp-2845	27	22	the	the	DET
fnp-2845	27	23	initiating	initiate	VERB
fnp-2845	27	24	factor	factor	NOUN
fnp-2845	27	25	(	(	PUNCT
fnp-2845	27	26	15	15	NUM
fnp-2845	27	27	-	-	SYM
fnp-2845	27	28	20	20	NUM
fnp-2845	27	29	)	)	PUNCT
fnp-2845	27	30	.	.	PUNCT
fnp-2845	28	1	a	a	DET
fnp-2845	28	2	competing	compete	VERB
fnp-2845	28	3	view	view	NOUN
fnp-2845	28	4	is	be	AUX
fnp-2845	28	5	offered	offer	VERB
fnp-2845	28	6	by	by	ADP
fnp-2845	28	7	others	other	NOUN
fnp-2845	28	8	who	who	PRON
fnp-2845	28	9	contend	contend	VERB
fnp-2845	28	10	that	that	SCONJ
fnp-2845	28	11	the	the	DET
fnp-2845	28	12	sequence	sequence	NOUN
fnp-2845	28	13	of	of	ADP
fnp-2845	28	14	pathological	pathological	ADJ
fnp-2845	28	15	events	event	NOUN
fnp-2845	28	16	begins	begin	VERB
fnp-2845	28	17	with	with	ADP
fnp-2845	28	18	neurofibrillary	neurofibrillary	ADJ
fnp-2845	28	19	pathology	pathology	NOUN
fnp-2845	28	20	(	(	PUNCT
fnp-2845	28	21	21	21	NUM
fnp-2845	28	22	,	,	PUNCT
fnp-2845	28	23	22	22	NUM
fnp-2845	28	24	)	)	PUNCT
fnp-2845	28	25	which	which	PRON
fnp-2845	28	26	precedes	precede	VERB
fnp-2845	28	27	the	the	DET
fnp-2845	28	28	formation	formation	NOUN
fnp-2845	28	29	of	of	ADP
fnp-2845	28	30	insoluble	insoluble	ADJ
fnp-2845	28	31	aβ	aβ	PRON
fnp-2845	28	32	pathology	pathology	NOUN
fnp-2845	28	33	(	(	PUNCT
fnp-2845	28	34	23	23	NUM
fnp-2845	28	35	)	)	PUNCT
fnp-2845	28	36	.	.	PUNCT
fnp-2845	29	1	indeed	indeed	ADV
fnp-2845	29	2	,	,	PUNCT
fnp-2845	29	3	there	there	PRON
fnp-2845	29	4	is	be	VERB
fnp-2845	29	5	evidence	evidence	NOUN
fnp-2845	29	6	that	that	SCONJ
fnp-2845	29	7	tau	tau	PROPN
fnp-2845	29	8	pathology	pathology	NOUN
fnp-2845	29	9	occurs	occur	VERB
fnp-2845	29	10	prior	prior	ADV
fnp-2845	29	11	to	to	ADP
fnp-2845	29	12	aβ	aβ	DET
fnp-2845	29	13	pathology	pathology	NOUN
fnp-2845	29	14	as	as	SCONJ
fnp-2845	29	15	it	it	PRON
fnp-2845	29	16	is	be	AUX
fnp-2845	29	17	more	more	ADV
fnp-2845	29	18	common	common	ADJ
fnp-2845	29	19	in	in	ADP
fnp-2845	29	20	the	the	DET
fnp-2845	29	21	brains	brain	NOUN
fnp-2845	29	22	of	of	ADP
fnp-2845	29	23	non	non	ADJ
fnp-2845	29	24	-	-	ADJ
fnp-2845	29	25	demented	demented	ADJ
fnp-2845	29	26	individuals	individual	NOUN
fnp-2845	29	27	(	(	PUNCT
fnp-2845	29	28	21	21	NUM
fnp-2845	29	29	)	)	PUNCT
fnp-2845	29	30	but	but	CCONJ
fnp-2845	29	31	this	this	PRON
fnp-2845	29	32	might	might	AUX
fnp-2845	29	33	represent	represent	VERB
fnp-2845	29	34	a	a	DET
fnp-2845	29	35	non	non	ADJ
fnp-2845	29	36	-	-	ADJ
fnp-2845	29	37	ad	ad	ADJ
fnp-2845	29	38	scenario	scenario	NOUN
fnp-2845	29	39	described	describe	VERB
fnp-2845	29	40	as	as	ADP
fnp-2845	29	41	primary	primary	ADJ
fnp-2845	29	42	age	age	NOUN
fnp-2845	29	43	-	-	PUNCT
fnp-2845	29	44	related	relate	VERB
fnp-2845	29	45	tauopathy	tauopathy	NOUN
fnp-2845	29	46	(	(	PUNCT
fnp-2845	29	47	part	part	NOUN
fnp-2845	29	48	)	)	PUNCT
fnp-2845	29	49	(	(	PUNCT
fnp-2845	29	50	24	24	NUM
fnp-2845	29	51	)	)	PUNCT
fnp-2845	29	52	.	.	PUNCT
fnp-2845	30	1	notwithstanding	notwithstanding	ADP
fnp-2845	30	2	the	the	DET
fnp-2845	30	3	order	order	NOUN
fnp-2845	30	4	of	of	ADP
fnp-2845	30	5	events	event	NOUN
fnp-2845	30	6	,	,	PUNCT
fnp-2845	30	7	both	both	DET
fnp-2845	30	8	hypotheses	hypothesis	NOUN
fnp-2845	30	9	suggest	suggest	VERB
fnp-2845	30	10	that	that	SCONJ
fnp-2845	30	11	an	an	DET
fnp-2845	30	12	activated	activate	VERB
fnp-2845	30	13	glial	glial	ADJ
fnp-2845	30	14	response	response	NOUN
fnp-2845	30	15	is	be	AUX
fnp-2845	30	16	an	an	DET
fnp-2845	30	17	integral	integral	ADJ
fnp-2845	30	18	component	component	NOUN
fnp-2845	30	19	of	of	ADP
fnp-2845	30	20	the	the	DET
fnp-2845	30	21	pathogenesis	pathogenesis	NOUN
fnp-2845	30	22	of	of	ADP
fnp-2845	30	23	ad	ad	NOUN
fnp-2845	30	24	.	.	PUNCT
fnp-2845	31	1	the	the	DET
fnp-2845	31	2	study	study	NOUN
fnp-2845	31	3	of	of	ADP
fnp-2845	31	4	microglia	microglia	ADJ
fnp-2845	31	5	morphology	morphology	NOUN
fnp-2845	31	6	in	in	ADP
fnp-2845	31	7	post	post	ADJ
fnp-2845	31	8	-	-	ADJ
fnp-2845	31	9	mortem	mortem	ADJ
fnp-2845	31	10	human	human	ADJ
fnp-2845	31	11	brain	brain	NOUN
fnp-2845	31	12	tissue	tissue	NOUN
fnp-2845	31	13	presents	present	VERB
fnp-2845	31	14	a	a	DET
fnp-2845	31	15	simple	simple	ADJ
fnp-2845	31	16	method	method	NOUN
fnp-2845	31	17	with	with	ADP
fnp-2845	31	18	which	which	PRON
fnp-2845	31	19	to	to	PART
fnp-2845	31	20	gauge	gauge	VERB
fnp-2845	31	21	the	the	DET
fnp-2845	31	22	involvement	involvement	NOUN
fnp-2845	31	23	of	of	ADP
fnp-2845	31	24	microglia	microglia	NOUN
fnp-2845	31	25	in	in	ADP
fnp-2845	31	26	instances	instance	NOUN
fnp-2845	31	27	of	of	ADP
fnp-2845	31	28	changed	change	VERB
fnp-2845	31	29	physiological	physiological	ADJ
fnp-2845	31	30	conditions	condition	NOUN
fnp-2845	31	31	or	or	CCONJ
fnp-2845	31	32	to	to	ADP
fnp-2845	31	33	the	the	DET
fnp-2845	31	34	development	development	NOUN
fnp-2845	31	35	of	of	ADP
fnp-2845	31	36	a	a	DET
fnp-2845	31	37	disease	disease	NOUN
fnp-2845	31	38	.	.	PUNCT
fnp-2845	32	1	microglia	microglia	ADJ
fnp-2845	32	2	with	with	ADP
fnp-2845	32	3	a	a	DET
fnp-2845	32	4	ramified	ramified	ADJ
fnp-2845	32	5	morphology	morphology	NOUN
fnp-2845	32	6	,	,	PUNCT
fnp-2845	32	7	characterised	characterise	VERB
fnp-2845	32	8	by	by	ADP
fnp-2845	32	9	thin	thin	ADJ
fnp-2845	32	10	,	,	PUNCT
fnp-2845	32	11	evenly	evenly	ADV
fnp-2845	32	12	distributed	distribute	VERB
fnp-2845	32	13	,	,	PUNCT
fnp-2845	32	14	highly	highly	ADV
fnp-2845	32	15	branched	branched	ADJ
fnp-2845	32	16	processes	process	NOUN
fnp-2845	32	17	with	with	ADP
fnp-2845	32	18	a	a	DET
fnp-2845	32	19	small	small	ADJ
fnp-2845	32	20	,	,	PUNCT
fnp-2845	32	21	spherical	spherical	ADJ
fnp-2845	32	22	soma	soma	NOUN
fnp-2845	32	23	,	,	PUNCT
fnp-2845	32	24	represent	represent	VERB
fnp-2845	32	25	the	the	DET
fnp-2845	32	26	healthy	healthy	ADJ
fnp-2845	32	27	cell	cell	NOUN
fnp-2845	32	28	population	population	NOUN
fnp-2845	32	29	(	(	PUNCT
fnp-2845	32	30	25	25	NUM
fnp-2845	32	31	-	-	SYM
fnp-2845	32	32	27	27	NUM
fnp-2845	32	33	)	)	PUNCT
fnp-2845	32	34	.	.	PUNCT
fnp-2845	33	1	activated	activate	VERB
fnp-2845	33	2	microglia	microglia	NOUN
fnp-2845	33	3	are	be	AUX
fnp-2845	33	4	characterised	characterise	VERB
fnp-2845	33	5	by	by	ADP
fnp-2845	33	6	reduced	reduce	VERB
fnp-2845	33	7	morphological	morphological	ADJ
fnp-2845	33	8	complexity	complexity	NOUN
fnp-2845	33	9	including	include	VERB
fnp-2845	33	10	hypertrophy	hypertrophy	NOUN
fnp-2845	33	11	of	of	ADP
fnp-2845	33	12	the	the	DET
fnp-2845	33	13	soma	soma	NOUN
fnp-2845	33	14	and	and	CCONJ
fnp-2845	33	15	processes	process	NOUN
fnp-2845	33	16	and	and	CCONJ
fnp-2845	33	17	may	may	AUX
fnp-2845	33	18	also	also	ADV
fnp-2845	33	19	display	display	VERB
fnp-2845	33	20	the	the	DET
fnp-2845	33	21	formation	formation	NOUN
fnp-2845	33	22	of	of	ADP
fnp-2845	33	23	distal	distal	ADJ
fnp-2845	33	24	phagosomes	phagosome	NOUN
fnp-2845	33	25	(	(	PUNCT
fnp-2845	33	26	23	23	NUM
fnp-2845	33	27	,	,	PUNCT
fnp-2845	33	28	25	25	NUM
fnp-2845	33	29	,	,	PUNCT
fnp-2845	33	30	28	28	NUM
fnp-2845	33	31	)	)	PUNCT
fnp-2845	33	32	.	.	PUNCT
fnp-2845	34	1	dystrophic	dystrophic	ADJ
fnp-2845	34	2	microglia	microglia	ADJ
fnp-2845	34	3	display	display	NOUN
fnp-2845	34	4	features	feature	VERB
fnp-2845	34	5	consistent	consistent	ADJ
fnp-2845	34	6	with	with	ADP
fnp-2845	34	7	cellular	cellular	ADJ
fnp-2845	34	8	senescence	senescence	NOUN
fnp-2845	34	9	(	(	PUNCT
fnp-2845	34	10	29	29	NUM
fnp-2845	34	11	)	)	PUNCT
fnp-2845	34	12	,	,	PUNCT
fnp-2845	34	13	including	include	VERB
fnp-2845	34	14	a	a	DET
fnp-2845	34	15	loss	loss	NOUN
fnp-2845	34	16	of	of	ADP
fnp-2845	34	17	processes	process	NOUN
fnp-2845	34	18	,	,	PUNCT
fnp-2845	34	19	tortuosity	tortuosity	NOUN
fnp-2845	34	20	of	of	ADP
fnp-2845	34	21	remaining	remain	VERB
fnp-2845	34	22	processes	process	NOUN
fnp-2845	34	23	,	,	PUNCT
fnp-2845	34	24	and	and	CCONJ
fnp-2845	34	25	discontinuous	discontinuous	ADJ
fnp-2845	34	26	iba1	iba1	NOUN
fnp-2845	34	27	-	-	PUNCT
fnp-2845	34	28	immunolabelling	immunolabelling	NOUN
fnp-2845	34	29	(	(	PUNCT
fnp-2845	34	30	30	30	NUM
fnp-2845	34	31	-	-	SYM
fnp-2845	34	32	32	32	NUM
fnp-2845	34	33	)	)	PUNCT
fnp-2845	34	34	.	.	PUNCT
fnp-2845	35	1	lastly	lastly	ADV
fnp-2845	35	2	,	,	PUNCT
fnp-2845	35	3	clusters	cluster	NOUN
fnp-2845	35	4	of	of	ADP
fnp-2845	35	5	activated	activate	VERB
fnp-2845	35	6	microglia	microglia	NOUN
fnp-2845	35	7	in	in	ADP
fnp-2845	35	8	ad	ad	NOUN
fnp-2845	35	9	have	have	AUX
fnp-2845	35	10	been	be	AUX
fnp-2845	35	11	noted	note	VERB
fnp-2845	35	12	previously	previously	ADV
fnp-2845	35	13	in	in	ADP
fnp-2845	35	14	post	post	ADJ
fnp-2845	35	15	-	-	ADJ
fnp-2845	35	16	mortem	mortem	ADJ
fnp-2845	35	17	human	human	ADJ
fnp-2845	35	18	brain	brain	NOUN
fnp-2845	35	19	tissue	tissue	NOUN
fnp-2845	35	20	and	and	CCONJ
fnp-2845	35	21	represent	represent	VERB
fnp-2845	35	22	the	the	DET
fnp-2845	35	23	direct	direct	ADJ
fnp-2845	35	24	interaction	interaction	NOUN
fnp-2845	35	25	between	between	ADP
fnp-2845	35	26	microglia	microglia	NOUN
fnp-2845	35	27	and	and	CCONJ
fnp-2845	35	28	aβ	aβ	NOUN
fnp-2845	35	29	and	and	CCONJ
fnp-2845	35	30	tau	tau	PROPN
fnp-2845	35	31	pathology	pathology	NOUN
fnp-2845	35	32	(	(	PUNCT
fnp-2845	35	33	10	10	NUM
fnp-2845	35	34	,	,	PUNCT
fnp-2845	35	35	32	32	NUM
fnp-2845	35	36	,	,	PUNCT
fnp-2845	35	37	33	33	NUM
fnp-2845	35	38	)	)	PUNCT
fnp-2845	35	39	.	.	PUNCT
fnp-2845	36	1	by	by	ADP
fnp-2845	36	2	investigating	investigate	VERB
fnp-2845	36	3	brain	brain	NOUN
fnp-2845	36	4	regions	region	NOUN
fnp-2845	36	5	differentially	differentially	ADV
fnp-2845	36	6	affected	affect	VERB
fnp-2845	36	7	by	by	ADP
fnp-2845	36	8	ad	ad	NOUN
fnp-2845	36	9	-	-	PUNCT
fnp-2845	36	10	type	type	NOUN
fnp-2845	36	11	pathology	pathology	NOUN
fnp-2845	36	12	in	in	ADP
fnp-2845	36	13	non	non	ADJ
fnp-2845	36	14	-	-	ADJ
fnp-2845	36	15	demented	demented	ADJ
fnp-2845	36	16	and	and	CCONJ
fnp-2845	36	17	demented	demented	ADJ
fnp-2845	36	18	individuals	individual	NOUN
fnp-2845	36	19	it	it	PRON
fnp-2845	36	20	may	may	AUX
fnp-2845	36	21	be	be	AUX
fnp-2845	36	22	possible	possible	ADJ
fnp-2845	36	23	to	to	PART
fnp-2845	36	24	model	model	VERB
fnp-2845	36	25	the	the	DET
fnp-2845	36	26	sequence	sequence	NOUN
fnp-2845	36	27	of	of	ADP
fnp-2845	36	28	pathological	pathological	ADJ
fnp-2845	36	29	changes	change	NOUN
fnp-2845	36	30	in	in	ADP
fnp-2845	36	31	the	the	DET
fnp-2845	36	32	disease	disease	NOUN
fnp-2845	36	33	,	,	PUNCT
fnp-2845	36	34	in	in	ADP
fnp-2845	36	35	particular	particular	ADJ
fnp-2845	36	36	the	the	DET
fnp-2845	36	37	activated	activate	VERB
fnp-2845	36	38	microglial	microglial	ADJ
fnp-2845	36	39	response	response	NOUN
fnp-2845	36	40	.	.	PUNCT
fnp-2845	37	1	previously	previously	ADV
fnp-2845	37	2	we	we	PRON
fnp-2845	37	3	demonstrated	demonstrate	VERB
fnp-2845	37	4	an	an	DET
fnp-2845	37	5	increased	increase	VERB
fnp-2845	37	6	density	density	NOUN
fnp-2845	37	7	of	of	ADP
fnp-2845	37	8	activated	activated	ADJ
fnp-2845	37	9	microglia	microglia	NOUN
fnp-2845	37	10	in	in	ADP
fnp-2845	37	11	the	the	DET
fnp-2845	37	12	inferior	inferior	ADJ
fnp-2845	37	13	temporal	temporal	ADJ
fnp-2845	37	14	cortex	cortex	NOUN
fnp-2845	37	15	(	(	PUNCT
fnp-2845	37	16	itc	itc	PROPN
fnp-2845	37	17	)	)	PUNCT
fnp-2845	37	18	of	of	ADP
fnp-2845	37	19	non	non	ADJ
fnp-2845	37	20	-	-	ADJ
fnp-2845	37	21	demented	demented	ADJ
fnp-2845	37	22	controls	control	NOUN
fnp-2845	37	23	with	with	ADP
fnp-2845	37	24	similar	similar	ADJ
fnp-2845	37	25	levels	level	NOUN
fnp-2845	37	26	of	of	ADP
fnp-2845	37	27	ad	ad	NOUN
fnp-2845	37	28	-	-	PUNCT
fnp-2845	37	29	type	type	NOUN
fnp-2845	37	30	pathology	pathology	NOUN
fnp-2845	37	31	(	(	PUNCT
fnp-2845	37	32	‘	'	PUNCT
fnp-2845	37	33	high	high	ADJ
fnp-2845	37	34	pathology	pathology	NOUN
fnp-2845	37	35	controls	control	NOUN
fnp-2845	37	36	’	'	PUNCT
fnp-2845	37	37	–	–	PUNCT
fnp-2845	37	38	hpcs	hpcs	PROPN
fnp-2845	37	39	)	)	PUNCT
fnp-2845	37	40	as	as	ADP
fnp-2845	37	41	clinically	clinically	ADV
fnp-2845	37	42	and	and	CCONJ
fnp-2845	37	43	neuropathologically	neuropathologically	ADV
fnp-2845	37	44	-	-	PUNCT
fnp-2845	37	45	confirmed	confirm	VERB
fnp-2845	37	46	ad	ad	NOUN
fnp-2845	37	47	cases	case	NOUN
fnp-2845	37	48	(	(	PUNCT
fnp-2845	37	49	26	26	NUM
fnp-2845	37	50	)	)	PUNCT
fnp-2845	37	51	.	.	PUNCT
fnp-2845	38	1	this	this	PRON
fnp-2845	38	2	suggested	suggest	VERB
fnp-2845	38	3	that	that	SCONJ
fnp-2845	38	4	the	the	DET
fnp-2845	38	5	microglial	microglial	ADJ
fnp-2845	38	6	response	response	NOUN
fnp-2845	38	7	occurs	occur	VERB
fnp-2845	38	8	in	in	ADP
fnp-2845	38	9	the	the	DET
fnp-2845	38	10	preclinical	preclinical	ADJ
fnp-2845	38	11	phases	phase	NOUN
fnp-2845	38	12	of	of	ADP
fnp-2845	38	13	ad	ad	NOUN
fnp-2845	38	14	but	but	CCONJ
fnp-2845	38	15	we	we	PRON
fnp-2845	38	16	wished	wish	VERB
fnp-2845	38	17	to	to	PART
fnp-2845	38	18	confirm	confirm	VERB
fnp-2845	38	19	this	this	DET
fnp-2845	38	20	finding	finding	NOUN
fnp-2845	38	21	in	in	ADP
fnp-2845	38	22	a	a	DET
fnp-2845	38	23	belatedly	belatedly	ADV
fnp-2845	38	24	affected	affect	VERB
fnp-2845	38	25	region	region	NOUN
fnp-2845	38	26	of	of	ADP
fnp-2845	38	27	the	the	DET
fnp-2845	38	28	ad	ad	NOUN
fnp-2845	38	29	brain	brain	NOUN
fnp-2845	38	30	,	,	PUNCT
fnp-2845	38	31	the	the	DET
fnp-2845	38	32	primary	primary	ADJ
fnp-2845	38	33	motor	motor	NOUN
fnp-2845	38	34	cortex	cortex	NOUN
fnp-2845	38	35	(	(	PUNCT
fnp-2845	38	36	pmc	pmc	PROPN
fnp-2845	38	37	)	)	PUNCT
fnp-2845	38	38	,	,	PUNCT
fnp-2845	38	39	compared	compare	VERB
fnp-2845	38	40	to	to	ADP
fnp-2845	38	41	an	an	DET
fnp-2845	38	42	earlier	early	ADJ
fnp-2845	38	43	and	and	CCONJ
fnp-2845	38	44	more	more	ADV
fnp-2845	38	45	severely	severely	ADV
fnp-2845	38	46	affected	affected	ADJ
fnp-2845	38	47	region	region	NOUN
fnp-2845	38	48	,	,	PUNCT
fnp-2845	38	49	the	the	DET
fnp-2845	38	50	itc	itc	PROPN
fnp-2845	38	51	,	,	PUNCT
fnp-2845	38	52	of	of	ADP
fnp-2845	38	53	the	the	DET
fnp-2845	38	54	same	same	ADJ
fnp-2845	38	55	cases	case	NOUN
fnp-2845	38	56	.	.	PUNCT
fnp-2845	39	1	further	far	ADV
fnp-2845	39	2	,	,	PUNCT
fnp-2845	39	3	we	we	PRON
fnp-2845	39	4	wished	wish	VERB
fnp-2845	39	5	to	to	PART
fnp-2845	39	6	determine	determine	VERB
fnp-2845	39	7	the	the	DET
fnp-2845	39	8	sequence	sequence	NOUN
fnp-2845	39	9	of	of	ADP
fnp-2845	39	10	aβ	aβ	PROPN
fnp-2845	39	11	,	,	PUNCT
fnp-2845	39	12	tau	tau	PROPN
fnp-2845	39	13	,	,	PUNCT
fnp-2845	39	14	and	and	CCONJ
fnp-2845	39	15	microglia	microglia	ADJ
fnp-2845	39	16	pathological	pathological	ADJ
fnp-2845	39	17	changes	change	NOUN
fnp-2845	39	18	that	that	PRON
fnp-2845	39	19	occur	occur	VERB
fnp-2845	39	20	in	in	ADP
fnp-2845	39	21	the	the	DET
fnp-2845	39	22	cortex	cortex	NOUN
fnp-2845	39	23	.	.	PUNCT
fnp-2845	40	1	the	the	DET
fnp-2845	40	2	findings	finding	NOUN
fnp-2845	40	3	here	here	ADV
fnp-2845	40	4	demonstrate	demonstrate	VERB
fnp-2845	40	5	that	that	SCONJ
fnp-2845	40	6	nascent	nascent	ADJ
fnp-2845	40	7	nts	nt	NOUN
fnp-2845	40	8	and	and	CCONJ
fnp-2845	40	9	dns	dns	NOUN
fnp-2845	40	10	in	in	ADP
fnp-2845	40	11	the	the	DET
fnp-2845	40	12	pmc	pmc	PROPN
fnp-2845	40	13	begin	begin	VERB
fnp-2845	40	14	early	early	ADV
fnp-2845	40	15	in	in	ADP
fnp-2845	40	16	the	the	DET
fnp-2845	40	17	pathogenesis	pathogenesis	NOUN
fnp-2845	40	18	of	of	ADP
fnp-2845	40	19	ad	ad	NOUN
fnp-2845	40	20	,	,	PUNCT
fnp-2845	40	21	but	but	CCONJ
fnp-2845	40	22	follow	follow	VERB
fnp-2845	40	23	the	the	DET
fnp-2845	40	24	clustering	clustering	NOUN
fnp-2845	40	25	of	of	ADP
fnp-2845	40	26	activated	activated	ADJ
fnp-2845	40	27	microglia	microglia	NOUN
fnp-2845	40	28	.	.	PUNCT
fnp-2845	41	1	by	by	ADP
fnp-2845	41	2	contrast	contrast	NOUN
fnp-2845	41	3	,	,	PUNCT
fnp-2845	41	4	looking	look	VERB
fnp-2845	41	5	at	at	ADP
fnp-2845	41	6	the	the	DET
fnp-2845	41	7	severely	severely	ADV
fnp-2845	41	8	affected	affect	VERB
fnp-2845	41	9	itc	itc	NOUN
fnp-2845	41	10	in	in	ADP
fnp-2845	41	11	the	the	DET
fnp-2845	41	12	same	same	ADJ
fnp-2845	41	13	cases	case	NOUN
fnp-2845	41	14	,	,	PUNCT
fnp-2845	41	15	findings	finding	NOUN
fnp-2845	41	16	suggest	suggest	VERB
fnp-2845	41	17	that	that	SCONJ
fnp-2845	41	18	microglial	microglial	ADJ
fnp-2845	41	19	clustering	clustering	NOUN
fnp-2845	41	20	at	at	ADP
fnp-2845	41	21	plaques	plaque	NOUN
fnp-2845	41	22	dissipates	dissipate	VERB
fnp-2845	41	23	once	once	ADV
fnp-2845	41	24	tau	tau	PROPN
fnp-2845	41	25	and	and	CCONJ
fnp-2845	41	26	aβ	aβ	PRON
fnp-2845	41	27	pathology	pathology	NOUN
fnp-2845	41	28	is	be	AUX
fnp-2845	41	29	long	long	ADV
fnp-2845	41	30	established	establish	VERB
fnp-2845	41	31	and	and	CCONJ
fnp-2845	41	32	there	there	PRON
fnp-2845	41	33	is	be	VERB
fnp-2845	41	34	also	also	ADV
fnp-2845	41	35	a	a	DET
fnp-2845	41	36	substantial	substantial	ADJ
fnp-2845	41	37	loss	loss	NOUN
fnp-2845	41	38	of	of	ADP
fnp-2845	41	39	iba1	iba1	PROPN
fnp-2845	41	40	-	-	PUNCT
fnp-2845	41	41	immunoreactivity	immunoreactivity	PROPN
fnp-2845	41	42	(	(	PUNCT
fnp-2845	41	43	26	26	NUM
fnp-2845	41	44	,	,	PUNCT
fnp-2845	41	45	34	34	NUM
fnp-2845	41	46	)	)	PUNCT
fnp-2845	41	47	.	.	PUNCT
fnp-2845	42	1	although	although	SCONJ
fnp-2845	42	2	an	an	DET
fnp-2845	42	3	early	early	ADJ
fnp-2845	42	4	toxic	toxic	ADJ
fnp-2845	42	5	microglial	microglial	ADJ
fnp-2845	42	6	gain	gain	NOUN
fnp-2845	42	7	of	of	ADP
fnp-2845	42	8	function	function	NOUN
fnp-2845	42	9	can	can	AUX
fnp-2845	42	10	not	not	PART
fnp-2845	42	11	be	be	AUX
fnp-2845	42	12	ruled	rule	VERB
fnp-2845	42	13	out	out	ADP
fnp-2845	42	14	,	,	PUNCT
fnp-2845	42	15	these	these	DET
fnp-2845	42	16	findings	finding	NOUN
fnp-2845	42	17	appear	appear	VERB
fnp-2845	42	18	most	most	ADV
fnp-2845	42	19	consistent	consistent	ADJ
fnp-2845	42	20	with	with	ADP
fnp-2845	42	21	a	a	DET
fnp-2845	42	22	scenario	scenario	NOUN
fnp-2845	42	23	where	where	SCONJ
fnp-2845	42	24	microglial	microglial	ADJ
fnp-2845	42	25	activation	activation	NOUN
fnp-2845	42	26	is	be	AUX
fnp-2845	42	27	neuroprotective	neuroprotective	ADJ
fnp-2845	42	28	early	early	ADV
fnp-2845	42	29	in	in	ADP
fnp-2845	42	30	the	the	DET
fnp-2845	42	31	pathogenesis	pathogenesis	NOUN
fnp-2845	42	32	of	of	ADP
fnp-2845	42	33	ad	ad	NOUN
fnp-2845	42	34	.	.	PUNCT
fnp-2845	43	1	we	we	PRON
fnp-2845	43	2	suggest	suggest	VERB
fnp-2845	43	3	that	that	SCONJ
fnp-2845	43	4	this	this	PRON
fnp-2845	43	5	is	be	AUX
fnp-2845	43	6	followed	follow	VERB
fnp-2845	43	7	by	by	ADP
fnp-2845	43	8	a	a	DET
fnp-2845	43	9	gradual	gradual	ADJ
fnp-2845	43	10	exhaustion	exhaustion	NOUN
fnp-2845	43	11	of	of	ADP
fnp-2845	43	12	microglial	microglial	ADJ
fnp-2845	43	13	function	function	NOUN
fnp-2845	43	14	that	that	PRON
fnp-2845	43	15	contributes	contribute	VERB
fnp-2845	43	16	to	to	ADP
fnp-2845	43	17	cognitive	cognitive	ADJ
fnp-2845	43	18	deterioration	deterioration	NOUN
fnp-2845	43	19	in	in	ADP
fnp-2845	43	20	the	the	DET
fnp-2845	43	21	ad	ad	NOUN
fnp-2845	43	22	brain	brain	NOUN
fnp-2845	43	23	.	.	PUNCT
fnp-2845	44	1	table	table	NOUN
fnp-2845	44	2	1	1	NUM
fnp-2845	44	3	.	.	PUNCT
fnp-2845	45	1	cohort	cohort	NOUN
fnp-2845	45	2	characteristics	characteristic	NOUN
fnp-2845	45	3	methods	method	NOUN
fnp-2845	45	4	this	this	DET
fnp-2845	45	5	study	study	NOUN
fnp-2845	45	6	was	be	AUX
fnp-2845	45	7	approved	approve	VERB
fnp-2845	45	8	by	by	ADP
fnp-2845	45	9	the	the	DET
fnp-2845	45	10	university	university	PROPN
fnp-2845	45	11	of	of	ADP
fnp-2845	45	12	sydney	sydney	PROPN
fnp-2845	45	13	’s	’s	PART
fnp-2845	45	14	human	human	PROPN
fnp-2845	45	15	research	research	PROPN
fnp-2845	45	16	ethics	ethic	NOUN
fnp-2845	45	17	committee	committee	PROPN
fnp-2845	45	18	(	(	PUNCT
fnp-2845	45	19	hrec#2015/477	hrec#2015/477	NOUN
fnp-2845	45	20	)	)	PUNCT
fnp-2845	45	21	.	.	PUNCT
fnp-2845	46	1	all	all	DET
fnp-2845	46	2	tissue	tissue	NOUN
fnp-2845	46	3	samples	sample	NOUN
fnp-2845	46	4	for	for	ADP
fnp-2845	46	5	this	this	DET
fnp-2845	46	6	study	study	NOUN
fnp-2845	46	7	,	,	PUNCT
fnp-2845	46	8	as	as	ADV
fnp-2845	46	9	well	well	ADV
fnp-2845	46	10	as	as	ADP
fnp-2845	46	11	demographic	demographic	ADJ
fnp-2845	46	12	and	and	CCONJ
fnp-2845	46	13	clinical	clinical	ADJ
fnp-2845	46	14	information	information	NOUN
fnp-2845	46	15	,	,	PUNCT
fnp-2845	46	16	were	be	AUX
fnp-2845	46	17	supplied	supply	VERB
fnp-2845	46	18	by	by	ADP
fnp-2845	46	19	the	the	DET
fnp-2845	46	20	new	new	ADJ
fnp-2845	46	21	south	south	PROPN
fnp-2845	46	22	wales	wales	PROPN
fnp-2845	46	23	brain	brain	NOUN
fnp-2845	46	24	tissue	tissue	NOUN
fnp-2845	46	25	resource	resource	NOUN
fnp-2845	46	26	centre	centre	NOUN
fnp-2845	46	27	(	(	PUNCT
fnp-2845	46	28	nswbtrc	nswbtrc	PROPN
fnp-2845	46	29	)	)	PUNCT
fnp-2845	46	30	and	and	CCONJ
fnp-2845	46	31	the	the	DET
fnp-2845	46	32	sydney	sydney	PROPN
fnp-2845	46	33	brain	brain	PROPN
fnp-2845	46	34	bank	bank	PROPN
fnp-2845	46	35	(	(	PUNCT
fnp-2845	46	36	sbb	sbb	PROPN
fnp-2845	46	37	)	)	PUNCT
fnp-2845	46	38	,	,	PUNCT
fnp-2845	46	39	collectively	collectively	ADV
fnp-2845	46	40	the	the	DET
fnp-2845	46	41	new	new	ADJ
fnp-2845	46	42	south	south	PROPN
fnp-2845	46	43	wales	wales	PROPN
fnp-2845	46	44	brain	brain	NOUN
fnp-2845	46	45	banks	bank	NOUN
fnp-2845	46	46	(	(	PUNCT
fnp-2845	46	47	nswbb	nswbb	NUM
fnp-2845	46	48	)	)	PUNCT
fnp-2845	46	49	,	,	PUNCT
fnp-2845	46	50	following	follow	VERB
fnp-2845	46	51	approval	approval	NOUN
fnp-2845	46	52	from	from	ADP
fnp-2845	46	53	their	their	PRON
fnp-2845	46	54	scientific	scientific	ADJ
fnp-2845	46	55	advisory	advisory	ADJ
fnp-2845	46	56	committee	committee	NOUN
fnp-2845	46	57	.	.	PUNCT
fnp-2845	47	1	methods	method	NOUN
fnp-2845	47	2	for	for	ADP
fnp-2845	47	3	case	case	NOUN
fnp-2845	47	4	ascertainment	ascertainment	NOUN
fnp-2845	47	5	and	and	CCONJ
fnp-2845	47	6	tissue	tissue	NOUN
fnp-2845	47	7	preparation	preparation	NOUN
fnp-2845	47	8	by	by	ADP
fnp-2845	47	9	nswbb	nswbb	PROPN
fnp-2845	47	10	have	have	AUX
fnp-2845	47	11	been	be	AUX
fnp-2845	47	12	previously	previously	ADV
fnp-2845	47	13	published	publish	VERB
fnp-2845	47	14	(	(	PUNCT
fnp-2845	47	15	35	35	NUM
fnp-2845	47	16	)	)	PUNCT
fnp-2845	47	17	.	.	PUNCT
fnp-2845	48	1	the	the	DET
fnp-2845	48	2	demographic	demographic	ADJ
fnp-2845	48	3	and	and	CCONJ
fnp-2845	48	4	clinicopathological	clinicopathological	ADJ
fnp-2845	48	5	characteristics	characteristic	NOUN
fnp-2845	48	6	of	of	ADP
fnp-2845	48	7	the	the	DET
fnp-2845	48	8	cohort	cohort	NOUN
fnp-2845	48	9	(	(	PUNCT
fnp-2845	48	10	table	table	NOUN
fnp-2845	48	11	1	1	NUM
fnp-2845	48	12	)	)	PUNCT
fnp-2845	48	13	and	and	CCONJ
fnp-2845	48	14	data	datum	NOUN
fnp-2845	48	15	from	from	ADP
fnp-2845	48	16	the	the	DET
fnp-2845	48	17	itc	itc	PROPN
fnp-2845	48	18	have	have	AUX
fnp-2845	48	19	been	be	AUX
fnp-2845	48	20	previously	previously	ADV
fnp-2845	48	21	published	publish	VERB
fnp-2845	48	22	(	(	PUNCT
fnp-2845	48	23	26	26	NUM
fnp-2845	48	24	)	)	PUNCT
fnp-2845	48	25	.	.	PUNCT
fnp-2845	49	1	immunofluorescence	immunofluorescence	NOUN
fnp-2845	49	2	immunofluorescence	immunofluorescence	NOUN
fnp-2845	49	3	staining	stain	VERB
fnp-2845	49	4	procedures	procedure	NOUN
fnp-2845	49	5	were	be	AUX
fnp-2845	49	6	performed	perform	VERB
fnp-2845	49	7	on	on	ADP
fnp-2845	49	8	free	free	ADV
fnp-2845	49	9	-	-	PUNCT
fnp-2845	49	10	floating	float	VERB
fnp-2845	49	11	45	45	NUM
fnp-2845	49	12	μm	μm	NUM
fnp-2845	49	13	fixed	fix	VERB
fnp-2845	49	14	sections	section	NOUN
fnp-2845	49	15	derived	derive	VERB
fnp-2845	49	16	from	from	ADP
fnp-2845	49	17	the	the	DET
fnp-2845	49	18	caudal	caudal	NOUN
fnp-2845	49	19	aspect	aspect	NOUN
fnp-2845	49	20	of	of	ADP
fnp-2845	49	21	the	the	DET
fnp-2845	49	22	superomedial	superomedial	ADJ
fnp-2845	49	23	area	area	NOUN
fnp-2845	49	24	of	of	ADP
fnp-2845	49	25	the	the	DET
fnp-2845	49	26	pmc	pmc	PROPN
fnp-2845	49	27	of	of	ADP
fnp-2845	49	28	controls	control	NOUN
fnp-2845	49	29	(	(	PUNCT
fnp-2845	49	30	n	n	NOUN
fnp-2845	49	31	=	=	NUM
fnp-2845	49	32	10	10	NUM
fnp-2845	49	33	)	)	PUNCT
fnp-2845	49	34	,	,	PUNCT
fnp-2845	49	35	hpcs	hpc	NOUN
fnp-2845	49	36	(	(	PUNCT
fnp-2845	49	37	n	n	NOUN
fnp-2845	49	38	=	=	SYM
fnp-2845	49	39	5	5	NUM
fnp-2845	49	40	)	)	PUNCT
fnp-2845	49	41	,	,	PUNCT
fnp-2845	49	42	and	and	CCONJ
fnp-2845	49	43	pathologically	pathologically	ADV
fnp-2845	49	44	confirmed	confirm	VERB
fnp-2845	49	45	ad	ad	NOUN
fnp-2845	49	46	cases	case	NOUN
fnp-2845	49	47	(	(	PUNCT
fnp-2845	49	48	n	n	NOUN
fnp-2845	49	49	=	=	SYM
fnp-2845	49	50	8)	8)	NUM
fnp-2845	49	51	as	as	ADP
fnp-2845	49	52	previously	previously	ADV
fnp-2845	49	53	described	describe	VERB
fnp-2845	49	54	(	(	PUNCT
fnp-2845	49	55	26	26	NUM
fnp-2845	49	56	)	)	PUNCT
fnp-2845	49	57	.	.	PUNCT
fnp-2845	50	1	double	double	ADJ
fnp-2845	50	2	-	-	PUNCT
fnp-2845	50	3	labelled	label	VERB
fnp-2845	50	4	sections	section	NOUN
fnp-2845	50	5	using	use	VERB
fnp-2845	50	6	antibodies	antibody	NOUN
fnp-2845	50	7	against	against	ADP
fnp-2845	50	8	aβ	aβ	NOUN
fnp-2845	50	9	,	,	PUNCT
fnp-2845	50	10	total	total	ADJ
fnp-2845	50	11	tau	tau	PROPN
fnp-2845	50	12	(	(	PUNCT
fnp-2845	50	13	ttau	ttau	PROPN
fnp-2845	50	14	)	)	PUNCT
fnp-2845	50	15	,	,	PUNCT
fnp-2845	50	16	and	and	CCONJ
fnp-2845	50	17	the	the	DET
fnp-2845	50	18	pan	pan	ADJ
fnp-2845	50	19	-	-	ADJ
fnp-2845	50	20	microglial	microglial	ADJ
fnp-2845	50	21	marker	marker	NOUN
fnp-2845	50	22	ionised	ionise	VERB
fnp-2845	50	23	calcium	calcium	NOUN
fnp-2845	50	24	-	-	PUNCT
fnp-2845	50	25	binding	bind	VERB
fnp-2845	50	26	adapter	adapter	NOUN
fnp-2845	50	27	molecule	molecule	NOUN
fnp-2845	50	28	1	1	NUM
fnp-2845	50	29	(	(	PUNCT
fnp-2845	50	30	iba1	iba1	PROPN
fnp-2845	50	31	)	)	PUNCT
fnp-2845	50	32	,	,	PUNCT
fnp-2845	50	33	were	be	AUX
fnp-2845	50	34	used	use	VERB
fnp-2845	50	35	for	for	ADP
fnp-2845	50	36	the	the	DET
fnp-2845	50	37	quantification	quantification	NOUN
fnp-2845	50	38	of	of	ADP
fnp-2845	50	39	aβ	aβ	PRON
fnp-2845	50	40	and	and	CCONJ
fnp-2845	50	41	tau	tau	PROPN
fnp-2845	50	42	loads	load	NOUN
fnp-2845	50	43	and	and	CCONJ
fnp-2845	50	44	microglial	microglial	ADJ
fnp-2845	50	45	morphological	morphological	ADJ
fnp-2845	50	46	subtypes	subtype	NOUN
fnp-2845	50	47	.	.	PUNCT
fnp-2845	51	1	for	for	ADP
fnp-2845	51	2	aβ	aβ	PRON
fnp-2845	51	3	and	and	CCONJ
fnp-2845	51	4	iba1	iba1	PROPN
fnp-2845	51	5	quantification	quantification	NOUN
fnp-2845	51	6	,	,	PUNCT
fnp-2845	51	7	heat	heat	NOUN
fnp-2845	51	8	-	-	PUNCT
fnp-2845	51	9	induced	induce	VERB
fnp-2845	51	10	epitope	epitope	NOUN
fnp-2845	51	11	retrieval	retrieval	NOUN
fnp-2845	51	12	was	be	AUX
fnp-2845	51	13	performed	perform	VERB
fnp-2845	51	14	using	use	VERB
fnp-2845	51	15	a	a	DET
fnp-2845	51	16	sodium	sodium	NOUN
fnp-2845	51	17	citrate	citrate	NOUN
fnp-2845	51	18	solution	solution	NOUN
fnp-2845	51	19	(	(	PUNCT
fnp-2845	51	20	ph	ph	NOUN
fnp-2845	51	21	8.5	8.5	NUM
fnp-2845	51	22	)	)	PUNCT
fnp-2845	51	23	at	at	ADP
fnp-2845	51	24	60	60	NUM
fnp-2845	51	25	°	°	NOUN
fnp-2845	51	26	c	c	NOUN
fnp-2845	51	27	overnight	overnight	ADV
fnp-2845	51	28	,	,	PUNCT
fnp-2845	51	29	followed	follow	VERB
fnp-2845	51	30	by	by	ADP
fnp-2845	51	31	a	a	DET
fnp-2845	51	32	12	12	NUM
fnp-2845	51	33	-	-	PUNCT
fnp-2845	51	34	minute	minute	NOUN
fnp-2845	51	35	formic	formic	ADJ
fnp-2845	51	36	acid	acid	NOUN
fnp-2845	51	37	(	(	PUNCT
fnp-2845	51	38	90	90	NUM
fnp-2845	51	39	%	%	NOUN
fnp-2845	51	40	)	)	PUNCT
fnp-2845	51	41	incubation	incubation	NOUN
fnp-2845	51	42	at	at	ADP
fnp-2845	51	43	room	room	NOUN
fnp-2845	51	44	temperature	temperature	NOUN
fnp-2845	51	45	.	.	PUNCT
fnp-2845	52	1	blocking	blocking	NOUN
fnp-2845	52	2	was	be	AUX
fnp-2845	52	3	performed	perform	VERB
fnp-2845	52	4	in	in	ADP
fnp-2845	52	5	10	10	NUM
fnp-2845	52	6	%	%	NOUN
fnp-2845	52	7	normal	normal	ADJ
fnp-2845	52	8	goat	goat	PROPN
fnp-2845	52	9	serum	serum	NOUN
fnp-2845	52	10	(	(	PUNCT
fnp-2845	52	11	gibco	gibco	NOUN
fnp-2845	52	12	#	#	SYM
fnp-2845	52	13	16210072	16210072	NUM
fnp-2845	52	14	)	)	PUNCT
fnp-2845	52	15	,	,	PUNCT
fnp-2845	52	16	and	and	CCONJ
fnp-2845	52	17	primary	primary	ADJ
fnp-2845	52	18	(	(	PUNCT
fnp-2845	52	19	mouse	mouse	NOUN
fnp-2845	52	20	aβ	aβ	PROPN
fnp-2845	52	21	,	,	PUNCT
fnp-2845	52	22	1:1000	1:1000	NUM
fnp-2845	52	23	,	,	PUNCT
fnp-2845	52	24	biolegend	biolegend	NOUN
fnp-2845	52	25	803002	803002	NUM
fnp-2845	52	26	;	;	PUNCT
fnp-2845	52	27	rabbit	rabbit	NOUN
fnp-2845	52	28	iba1	iba1	PROPN
fnp-2845	52	29	,	,	PUNCT
fnp-2845	52	30	1:1000	1:1000	NUM
fnp-2845	52	31	,	,	PUNCT
fnp-2845	52	32	wako	wako	PROPN
fnp-2845	52	33	019	019	NUM
fnp-2845	52	34	-	-	SYM
fnp-2845	52	35	19741	19741	NUM
fnp-2845	52	36	)	)	PUNCT
fnp-2845	52	37	and	and	CCONJ
fnp-2845	52	38	secondary	secondary	ADJ
fnp-2845	52	39	(	(	PUNCT
fnp-2845	52	40	1:200	1:200	NUM
fnp-2845	52	41	;	;	PUNCT
fnp-2845	52	42	thermo	thermo	NOUN
fnp-2845	52	43	scientific	scientific	NOUN
fnp-2845	52	44	:	:	PUNCT
fnp-2845	53	1	alexa	alexa	NOUN
fnp-2845	53	2	fluor	fluor	NOUN
fnp-2845	53	3	(	(	PUNCT
fnp-2845	53	4	af	af	PROPN
fnp-2845	53	5	)	)	PUNCT
fnp-2845	53	6	488	488	NUM
fnp-2845	53	7	goat	goat	PROPN
fnp-2845	53	8	anti	anti	NOUN
fnp-2845	53	9	-	-	NOUN
fnp-2845	53	10	mouse	mouse	ADJ
fnp-2845	53	11	,	,	PUNCT
fnp-2845	53	12	#	#	NOUN
fnp-2845	53	13	a11001	a11001	ADJ
fnp-2845	53	14	;	;	PUNCT
fnp-2845	53	15	af	af	PROPN
fnp-2845	53	16	568	568	NUM
fnp-2845	53	17	goat	goat	PROPN
fnp-2845	53	18	anti	anti	NOUN
fnp-2845	53	19	-	-	NOUN
fnp-2845	53	20	rabbit	rabbit	ADJ
fnp-2845	53	21	,	,	PUNCT
fnp-2845	53	22	#	#	NOUN
fnp-2845	53	23	a11011	a11011	NOUN
fnp-2845	53	24	)	)	PUNCT
fnp-2845	53	25	antibody	antibody	NOUN
fnp-2845	53	26	incubations	incubation	NOUN
fnp-2845	53	27	were	be	AUX
fnp-2845	53	28	performed	perform	VERB
fnp-2845	53	29	at	at	ADP
fnp-2845	53	30	4	4	NUM
fnp-2845	53	31	°	°	ADP
fnp-2845	53	32	c	c	NOUN
fnp-2845	53	33	with	with	ADP
fnp-2845	53	34	gentle	gentle	ADJ
fnp-2845	53	35	agitation	agitation	NOUN
fnp-2845	53	36	.	.	PUNCT
fnp-2845	54	1	nuclear	nuclear	ADJ
fnp-2845	54	2	counterstaining	counterstaining	NOUN
fnp-2845	54	3	was	be	AUX
fnp-2845	54	4	performed	perform	VERB
fnp-2845	54	5	in	in	ADP
fnp-2845	54	6	the	the	DET
fnp-2845	54	7	last	last	ADJ
fnp-2845	54	8	40	40	NUM
fnp-2845	54	9	minutes	minute	NOUN
fnp-2845	54	10	of	of	ADP
fnp-2845	54	11	the	the	DET
fnp-2845	54	12	secondary	secondary	ADJ
fnp-2845	54	13	antibody	antibody	NOUN
fnp-2845	54	14	incubation	incubation	NOUN
fnp-2845	54	15	by	by	ADP
fnp-2845	54	16	the	the	DET
fnp-2845	54	17	addition	addition	NOUN
fnp-2845	54	18	of	of	ADP
fnp-2845	54	19	hoechst	hoechst	ADJ
fnp-2845	54	20	33342	33342	NUM
fnp-2845	54	21	dye	dye	NOUN
fnp-2845	54	22	(	(	PUNCT
fnp-2845	54	23	1	1	NUM
fnp-2845	54	24	µg	µg	NOUN
fnp-2845	54	25	/	/	SYM
fnp-2845	54	26	ml	ml	NOUN
fnp-2845	54	27	;	;	PUNCT
fnp-2845	54	28	thermo	thermo	NOUN
fnp-2845	54	29	scientific	scientific	NOUN
fnp-2845	54	30	62249	62249	NUM
fnp-2845	54	31	)	)	PUNCT
fnp-2845	54	32	.	.	PUNCT
fnp-2845	55	1	sections	section	NOUN
fnp-2845	55	2	were	be	AUX
fnp-2845	55	3	mounted	mount	VERB
fnp-2845	55	4	using	use	VERB
fnp-2845	55	5	prolong	prolong	ADJ
fnp-2845	55	6	diamond	diamond	NOUN
fnp-2845	55	7	antifade	antifade	NOUN
fnp-2845	55	8	(	(	PUNCT
fnp-2845	55	9	invitrogen	invitrogen	PROPN
fnp-2845	55	10	p36961	p36961	PROPN
fnp-2845	55	11	)	)	PUNCT
fnp-2845	55	12	.	.	PUNCT
fnp-2845	56	1	double	double	ADJ
fnp-2845	56	2	-	-	PUNCT
fnp-2845	56	3	immunolabelling	immunolabelling	NOUN
fnp-2845	56	4	of	of	ADP
fnp-2845	56	5	ttau	ttau	PROPN
fnp-2845	56	6	(	(	PUNCT
fnp-2845	56	7	rabbit	rabbit	NOUN
fnp-2845	56	8	;	;	PUNCT
fnp-2845	56	9	1:500	1:500	NUM
fnp-2845	56	10	;	;	PUNCT
fnp-2845	56	11	dako	dako	PROPN
fnp-2845	56	12	k9ja	k9ja	NOUN
fnp-2845	56	13	/	/	SYM
fnp-2845	56	14	a0024	a0024	NOUN
fnp-2845	56	15	)	)	PUNCT
fnp-2845	56	16	and	and	CCONJ
fnp-2845	56	17	iba1	iba1	PROPN
fnp-2845	56	18	(	(	PUNCT
fnp-2845	56	19	mouse	mouse	NOUN
fnp-2845	56	20	;	;	PUNCT
fnp-2845	56	21	1:50	1:50	NUM
fnp-2845	56	22	;	;	PUNCT
fnp-2845	56	23	millipore	millipore	PROPN
fnp-2845	56	24	mabn92	mabn92	PROPN
fnp-2845	56	25	)	)	PUNCT
fnp-2845	56	26	was	be	AUX
fnp-2845	56	27	carried	carry	VERB
fnp-2845	56	28	out	out	ADP
fnp-2845	56	29	as	as	ADP
fnp-2845	56	30	previously	previously	ADV
fnp-2845	56	31	described	describe	VERB
fnp-2845	56	32	(	(	PUNCT
fnp-2845	56	33	34	34	NUM
fnp-2845	56	34	)	)	PUNCT
fnp-2845	56	35	.	.	PUNCT
fnp-2845	57	1	ttau	ttau	AUX
fnp-2845	57	2	immunostaining	immunostaine	VERB
fnp-2845	57	3	of	of	ADP
fnp-2845	57	4	nfts	nft	NOUN
fnp-2845	57	5	,	,	PUNCT
fnp-2845	57	6	nts	nt	NOUN
fnp-2845	57	7	,	,	PUNCT
fnp-2845	57	8	and	and	CCONJ
fnp-2845	57	9	dns	dns	NOUN
fnp-2845	57	10	has	have	AUX
fnp-2845	57	11	previously	previously	ADV
fnp-2845	57	12	been	be	AUX
fnp-2845	57	13	demonstrated	demonstrate	VERB
fnp-2845	57	14	to	to	PART
fnp-2845	57	15	give	give	VERB
fnp-2845	57	16	comparable	comparable	ADJ
fnp-2845	57	17	immunostaining	immunostaining	NOUN
fnp-2845	57	18	to	to	ADP
fnp-2845	57	19	standard	standard	ADJ
fnp-2845	57	20	phosphotau	phosphotau	ADJ
fnp-2845	57	21	antibodies	antibody	NOUN
fnp-2845	57	22	(	(	PUNCT
fnp-2845	57	23	12e8	12e8	NUM
fnp-2845	57	24	and	and	CCONJ
fnp-2845	57	25	at8	at8	PROPN
fnp-2845	57	26	)	)	PUNCT
fnp-2845	57	27	(	(	PUNCT
fnp-2845	57	28	36	36	NUM
fnp-2845	57	29	)	)	PUNCT
fnp-2845	57	30	.	.	PUNCT
fnp-2845	58	1	briefly	briefly	NOUN
fnp-2845	58	2	,	,	PUNCT
fnp-2845	58	3	heat	heat	NOUN
fnp-2845	58	4	-	-	PUNCT
fnp-2845	58	5	retrieval	retrieval	NOUN
fnp-2845	58	6	was	be	AUX
fnp-2845	58	7	performed	perform	VERB
fnp-2845	58	8	with	with	ADP
fnp-2845	58	9	sodium	sodium	NOUN
fnp-2845	58	10	citrate	citrate	NOUN
fnp-2845	58	11	(	(	PUNCT
fnp-2845	58	12	ph	ph	NOUN
fnp-2845	58	13	6.0	6.0	NUM
fnp-2845	58	14	)	)	PUNCT
fnp-2845	58	15	for	for	ADP
fnp-2845	58	16	10	10	NUM
fnp-2845	58	17	minutes	minute	NOUN
fnp-2845	58	18	at	at	ADP
fnp-2845	58	19	100	100	NUM
fnp-2845	58	20	°	°	NOUN
fnp-2845	58	21	c	c	NOUN
fnp-2845	58	22	,	,	PUNCT
fnp-2845	58	23	before	before	ADP
fnp-2845	58	24	permeabilising	permeabilise	VERB
fnp-2845	58	25	,	,	PUNCT
fnp-2845	58	26	blocking	block	VERB
fnp-2845	58	27	with	with	ADP
fnp-2845	58	28	bsa	bsa	NOUN
fnp-2845	58	29	,	,	PUNCT
fnp-2845	58	30	and	and	CCONJ
fnp-2845	58	31	incubating	incubate	VERB
fnp-2845	58	32	in	in	ADP
fnp-2845	58	33	primary	primary	ADJ
fnp-2845	58	34	antibodies	antibody	NOUN
fnp-2845	58	35	for	for	ADP
fnp-2845	58	36	three	three	NUM
fnp-2845	58	37	hours	hour	NOUN
fnp-2845	58	38	at	at	ADP
fnp-2845	58	39	room	room	NOUN
fnp-2845	58	40	temperature	temperature	NOUN
fnp-2845	58	41	or	or	CCONJ
fnp-2845	58	42	overnight	overnight	ADV
fnp-2845	58	43	at	at	ADP
fnp-2845	58	44	4	4	NUM
fnp-2845	58	45	°	°	NOUN
fnp-2845	58	46	c	c	NOUN
fnp-2845	58	47	,	,	PUNCT
fnp-2845	58	48	and	and	CCONJ
fnp-2845	58	49	finally	finally	ADV
fnp-2845	58	50	incubating	incubate	VERB
fnp-2845	58	51	in	in	ADP
fnp-2845	58	52	secondary	secondary	ADJ
fnp-2845	58	53	antibodies	antibody	NOUN
fnp-2845	58	54	(	(	PUNCT
fnp-2845	58	55	1:200	1:200	NUM
fnp-2845	58	56	;	;	PUNCT
fnp-2845	58	57	invitrogen	invitrogen	PROPN
fnp-2845	58	58	:	:	PUNCT
fnp-2845	58	59	af555	af555	PROPN
fnp-2845	58	60	goat	goat	PROPN
fnp-2845	58	61	anti	anti	PROPN
fnp-2845	58	62	-	-	NOUN
fnp-2845	58	63	mouse	mouse	ADJ
fnp-2845	58	64	,	,	PUNCT
fnp-2845	58	65	a214424	a214424	PROPN
fnp-2845	58	66	;	;	PUNCT
fnp-2845	58	67	af647	af647	PROPN
fnp-2845	58	68	goat	goat	PROPN
fnp-2845	58	69	anti	anti	NOUN
fnp-2845	58	70	-	-	NOUN
fnp-2845	58	71	rabbit	rabbit	ADJ
fnp-2845	58	72	,	,	PUNCT
fnp-2845	58	73	a21244	a21244	NOUN
fnp-2845	58	74	)	)	PUNCT
fnp-2845	58	75	.	.	PUNCT
fnp-2845	59	1	hoechst	hoechst	PROPN
fnp-2845	59	2	33342	33342	NUM
fnp-2845	59	3	was	be	AUX
fnp-2845	59	4	added	add	VERB
fnp-2845	59	5	to	to	PART
fnp-2845	59	6	counterstain	counterstain	VERB
fnp-2845	59	7	nuclei	nucleus	NOUN
fnp-2845	59	8	and	and	CCONJ
fnp-2845	59	9	sections	section	NOUN
fnp-2845	59	10	were	be	AUX
fnp-2845	59	11	mounted	mount	VERB
fnp-2845	59	12	in	in	ADP
fnp-2845	59	13	prolong	prolong	ADJ
fnp-2845	59	14	gold	gold	NOUN
fnp-2845	59	15	antifade	antifade	NOUN
fnp-2845	59	16	.	.	PUNCT
fnp-2845	60	1	image	image	NOUN
fnp-2845	60	2	acquisition	acquisition	NOUN
fnp-2845	60	3	and	and	CCONJ
fnp-2845	60	4	analysis	analysis	NOUN
fnp-2845	60	5	aβ	aβ	NOUN
fnp-2845	60	6	and	and	CCONJ
fnp-2845	60	7	iba1	iba1	VERB
fnp-2845	60	8	double	double	ADV
fnp-2845	60	9	-	-	PUNCT
fnp-2845	60	10	labelled	label	VERB
fnp-2845	60	11	sections	section	NOUN
fnp-2845	60	12	were	be	AUX
fnp-2845	60	13	imaged	image	VERB
fnp-2845	60	14	using	use	VERB
fnp-2845	60	15	a	a	DET
fnp-2845	60	16	zeiss	zeiss	PROPN
fnp-2845	60	17	lsm	lsm	PROPN
fnp-2845	60	18	800	800	NUM
fnp-2845	60	19	confocal	confocal	ADJ
fnp-2845	60	20	microscope	microscope	NOUN
fnp-2845	60	21	using	use	VERB
fnp-2845	60	22	the	the	DET
fnp-2845	60	23	‘	'	PUNCT
fnp-2845	60	24	tile	tile	NOUN
fnp-2845	60	25	scan	scan	NOUN
fnp-2845	60	26	’	'	PUNCT
fnp-2845	60	27	function	function	NOUN
fnp-2845	60	28	at	at	ADP
fnp-2845	60	29	the	the	DET
fnp-2845	60	30	advanced	advanced	ADJ
fnp-2845	60	31	microscopy	microscopy	NOUN
fnp-2845	60	32	facility	facility	NOUN
fnp-2845	60	33	,	,	PUNCT
fnp-2845	60	34	bosch	bosch	PROPN
fnp-2845	60	35	institute	institute	PROPN
fnp-2845	60	36	,	,	PUNCT
fnp-2845	60	37	the	the	DET
fnp-2845	60	38	university	university	PROPN
fnp-2845	60	39	of	of	ADP
fnp-2845	60	40	sydney	sydney	PROPN
fnp-2845	60	41	.	.	PUNCT
fnp-2845	61	1	a	a	DET
fnp-2845	61	2	previously	previously	ADV
fnp-2845	61	3	validated	validate	VERB
fnp-2845	61	4	modified	modify	VERB
fnp-2845	61	5	disector	disector	NOUN
fnp-2845	61	6	sampling	sample	VERB
fnp-2845	61	7	approach	approach	NOUN
fnp-2845	61	8	that	that	PRON
fnp-2845	61	9	utilises	utilise	VERB
fnp-2845	61	10	one	one	NUM
fnp-2845	61	11	section	section	NOUN
fnp-2845	61	12	per	per	ADP
fnp-2845	61	13	individual	individual	NOUN
fnp-2845	61	14	was	be	AUX
fnp-2845	61	15	used	use	VERB
fnp-2845	61	16	here	here	ADV
fnp-2845	61	17	for	for	ADP
fnp-2845	61	18	the	the	DET
fnp-2845	61	19	analysis	analysis	NOUN
fnp-2845	61	20	of	of	ADP
fnp-2845	61	21	the	the	DET
fnp-2845	61	22	aβ	aβ	NOUN
fnp-2845	61	23	and	and	CCONJ
fnp-2845	61	24	iba1	iba1	PROPN
fnp-2845	61	25	immunostained	immunostaine	VERB
fnp-2845	61	26	sections	section	NOUN
fnp-2845	61	27	(	(	PUNCT
fnp-2845	61	28	37	37	NUM
fnp-2845	61	29	)	)	PUNCT
fnp-2845	61	30	.	.	PUNCT
fnp-2845	62	1	briefly	briefly	NOUN
fnp-2845	62	2	,	,	PUNCT
fnp-2845	62	3	a	a	DET
fnp-2845	62	4	total	total	NOUN
fnp-2845	62	5	of	of	ADP
fnp-2845	62	6	three	three	NUM
fnp-2845	62	7	cortical	cortical	ADJ
fnp-2845	62	8	strips	strip	NOUN
fnp-2845	62	9	per	per	ADP
fnp-2845	62	10	section	section	NOUN
fnp-2845	62	11	from	from	ADP
fnp-2845	62	12	areas	area	NOUN
fnp-2845	62	13	where	where	SCONJ
fnp-2845	62	14	the	the	DET
fnp-2845	62	15	pial	pial	ADJ
fnp-2845	62	16	surface	surface	NOUN
fnp-2845	62	17	and	and	CCONJ
fnp-2845	62	18	the	the	DET
fnp-2845	62	19	grey	grey	ADJ
fnp-2845	62	20	-	-	PUNCT
fnp-2845	62	21	white	white	ADJ
fnp-2845	62	22	boundary	boundary	NOUN
fnp-2845	62	23	were	be	AUX
fnp-2845	62	24	strictly	strictly	ADV
fnp-2845	62	25	in	in	ADP
fnp-2845	62	26	parallel	parallel	NOUN
fnp-2845	62	27	were	be	AUX
fnp-2845	62	28	acquired	acquire	VERB
fnp-2845	62	29	for	for	ADP
fnp-2845	62	30	the	the	DET
fnp-2845	62	31	quantification	quantification	NOUN
fnp-2845	62	32	of	of	ADP
fnp-2845	62	33	microglia	microglia	NOUN
fnp-2845	62	34	,	,	PUNCT
fnp-2845	62	35	aβ	aβ	DET
fnp-2845	62	36	plaques	plaque	NOUN
fnp-2845	62	37	and	and	CCONJ
fnp-2845	62	38	aβ	aβ	NOUN
fnp-2845	62	39	-	-	PUNCT
fnp-2845	62	40	positive	positive	ADJ
fnp-2845	62	41	pixels	pixel	NOUN
fnp-2845	62	42	.	.	PUNCT
fnp-2845	63	1	these	these	DET
fnp-2845	63	2	cortical	cortical	ADJ
fnp-2845	63	3	strips	strip	NOUN
fnp-2845	63	4	were	be	AUX
fnp-2845	63	5	constructed	construct	VERB
fnp-2845	63	6	of	of	ADP
fnp-2845	63	7	serial	serial	ADJ
fnp-2845	63	8	images	image	NOUN
fnp-2845	63	9	500	500	NUM
fnp-2845	63	10	μm	μm	NOUN
fnp-2845	63	11	in	in	ADP
fnp-2845	63	12	width	width	NOUN
fnp-2845	63	13	,	,	PUNCT
fnp-2845	63	14	6	6	NUM
fnp-2845	63	15	μm	μm	NOUN
fnp-2845	63	16	in	in	ADP
fnp-2845	63	17	z	z	NOUN
fnp-2845	63	18	-	-	PUNCT
fnp-2845	63	19	depth	depth	NOUN
fnp-2845	63	20	with	with	ADP
fnp-2845	63	21	three	three	NUM
fnp-2845	63	22	z	z	NOUN
fnp-2845	63	23	-	-	PUNCT
fnp-2845	63	24	slices	slice	NOUN
fnp-2845	63	25	(	(	PUNCT
fnp-2845	63	26	z	z	NOUN
fnp-2845	63	27	-	-	PUNCT
fnp-2845	63	28	step	step	NOUN
fnp-2845	63	29	=	=	SYM
fnp-2845	63	30	3	3	NUM
fnp-2845	63	31	μm	μm	NUM
fnp-2845	63	32	)	)	PUNCT
fnp-2845	63	33	,	,	PUNCT
fnp-2845	63	34	spanning	span	VERB
fnp-2845	63	35	all	all	PRON
fnp-2845	63	36	of	of	ADP
fnp-2845	63	37	the	the	DET
fnp-2845	63	38	cortical	cortical	ADJ
fnp-2845	63	39	laminae	laminae	NOUN
fnp-2845	63	40	of	of	ADP
fnp-2845	63	41	the	the	DET
fnp-2845	63	42	pmc	pmc	PROPN
fnp-2845	63	43	using	use	VERB
fnp-2845	63	44	a	a	DET
fnp-2845	63	45	20×/0.8	20×/0.8	ADJ
fnp-2845	63	46	numerical	numerical	ADJ
fnp-2845	63	47	aperture	aperture	NOUN
fnp-2845	63	48	(	(	PUNCT
fnp-2845	63	49	na	na	NOUN
fnp-2845	63	50	)	)	PUNCT
fnp-2845	63	51	objective	objective	NOUN
fnp-2845	63	52	.	.	PUNCT
fnp-2845	64	1	clusters	cluster	NOUN
fnp-2845	64	2	of	of	ADP
fnp-2845	64	3	microglia	microglia	ADJ
fnp-2845	64	4	and	and	CCONJ
fnp-2845	64	5	individual	individual	ADJ
fnp-2845	64	6	microglia	microglia	NOUN
fnp-2845	64	7	,	,	PUNCT
fnp-2845	64	8	which	which	PRON
fnp-2845	64	9	were	be	AUX
fnp-2845	64	10	categorised	categorise	VERB
fnp-2845	64	11	as	as	ADP
fnp-2845	64	12	having	have	VERB
fnp-2845	64	13	either	either	CCONJ
fnp-2845	64	14	a	a	DET
fnp-2845	64	15	ramified	ramify	VERB
fnp-2845	64	16	,	,	PUNCT
fnp-2845	64	17	activated	activate	VERB
fnp-2845	64	18	,	,	PUNCT
fnp-2845	64	19	or	or	CCONJ
fnp-2845	64	20	dystrophic	dystrophic	ADJ
fnp-2845	64	21	morphology	morphology	NOUN
fnp-2845	64	22	as	as	SCONJ
fnp-2845	64	23	previously	previously	ADV
fnp-2845	64	24	described	describe	VERB
fnp-2845	64	25	(	(	PUNCT
fnp-2845	64	26	26	26	NUM
fnp-2845	64	27	)	)	PUNCT
fnp-2845	64	28	,	,	PUNCT
fnp-2845	64	29	were	be	AUX
fnp-2845	64	30	enumerated	enumerate	VERB
fnp-2845	64	31	in	in	ADP
fnp-2845	64	32	image	image	NOUN
fnp-2845	64	33	analysis	analysis	NOUN
fnp-2845	64	34	software	software	NOUN
fnp-2845	64	35	(	(	PUNCT
fnp-2845	64	36	fiji	fiji	PROPN
fnp-2845	64	37	;	;	PUNCT
fnp-2845	64	38	nih	nih	PROPN
fnp-2845	64	39	)	)	PUNCT
fnp-2845	64	40	.	.	PUNCT
fnp-2845	65	1	the	the	DET
fnp-2845	65	2	terminology	terminology	NOUN
fnp-2845	65	3	used	use	VERB
fnp-2845	65	4	to	to	PART
fnp-2845	65	5	describe	describe	VERB
fnp-2845	65	6	the	the	DET
fnp-2845	65	7	different	different	ADJ
fnp-2845	65	8	populations	population	NOUN
fnp-2845	65	9	of	of	ADP
fnp-2845	65	10	morphologically	morphologically	ADV
fnp-2845	65	11	diverse	diverse	ADJ
fnp-2845	65	12	populations	population	NOUN
fnp-2845	65	13	of	of	ADP
fnp-2845	65	14	microglia	microglia	NOUN
fnp-2845	65	15	was	be	AUX
fnp-2845	65	16	informed	inform	VERB
fnp-2845	65	17	by	by	ADP
fnp-2845	65	18	previous	previous	ADJ
fnp-2845	65	19	investigations	investigation	NOUN
fnp-2845	65	20	(	(	PUNCT
fnp-2845	65	21	25	25	NUM
fnp-2845	65	22	,	,	PUNCT
fnp-2845	65	23	28	28	NUM
fnp-2845	65	24	,	,	PUNCT
fnp-2845	65	25	30	30	NUM
fnp-2845	65	26	)	)	PUNCT
fnp-2845	65	27	.	.	PUNCT
fnp-2845	66	1	microglia	microglia	ADJ
fnp-2845	66	2	with	with	ADP
fnp-2845	66	3	thin	thin	ADJ
fnp-2845	66	4	,	,	PUNCT
fnp-2845	66	5	highly	highly	ADV
fnp-2845	66	6	branched	branched	ADJ
fnp-2845	66	7	processes	process	NOUN
fnp-2845	66	8	,	,	PUNCT
fnp-2845	66	9	and	and	CCONJ
fnp-2845	66	10	a	a	DET
fnp-2845	66	11	spherical	spherical	ADJ
fnp-2845	66	12	nucleus	nucleus	NOUN
fnp-2845	66	13	were	be	AUX
fnp-2845	66	14	categorised	categorise	VERB
fnp-2845	66	15	as	as	ADP
fnp-2845	66	16	‘	'	PUNCT
fnp-2845	66	17	ramified	ramify	VERB
fnp-2845	66	18	’	'	PUNCT
fnp-2845	66	19	.	.	PUNCT
fnp-2845	67	1	‘	'	PUNCT
fnp-2845	67	2	activated	activate	VERB
fnp-2845	67	3	’	'	PUNCT
fnp-2845	67	4	microglia	microglia	NOUN
fnp-2845	67	5	(	(	PUNCT
fnp-2845	67	6	previously	previously	ADV
fnp-2845	67	7	termed	term	VERB
fnp-2845	67	8	‘	'	PUNCT
fnp-2845	67	9	deramified	deramified	ADJ
fnp-2845	67	10	’	'	PUNCT
fnp-2845	67	11	(	(	PUNCT
fnp-2845	67	12	34	34	NUM
fnp-2845	67	13	)	)	PUNCT
fnp-2845	67	14	)	)	PUNCT
fnp-2845	67	15	included	include	VERB
fnp-2845	67	16	those	those	DET
fnp-2845	67	17	cells	cell	NOUN
fnp-2845	67	18	that	that	PRON
fnp-2845	67	19	displayed	display	VERB
fnp-2845	67	20	hypertrophy	hypertrophy	NOUN
fnp-2845	67	21	of	of	ADP
fnp-2845	67	22	the	the	DET
fnp-2845	67	23	soma	soma	NOUN
fnp-2845	67	24	or	or	CCONJ
fnp-2845	67	25	processes	process	NOUN
fnp-2845	67	26	with	with	ADP
fnp-2845	67	27	retraction	retraction	NOUN
fnp-2845	67	28	of	of	ADP
fnp-2845	67	29	secondary	secondary	ADJ
fnp-2845	67	30	or	or	CCONJ
fnp-2845	67	31	tertiary	tertiary	ADJ
fnp-2845	67	32	processes	process	NOUN
fnp-2845	67	33	.	.	PUNCT
fnp-2845	68	1	‘	'	PUNCT
fnp-2845	68	2	dystrophic	dystrophic	ADJ
fnp-2845	68	3	microglia	microglia	NOUN
fnp-2845	68	4	’	'	PUNCT
fnp-2845	68	5	were	be	AUX
fnp-2845	68	6	identified	identify	VERB
fnp-2845	68	7	on	on	ADP
fnp-2845	68	8	the	the	DET
fnp-2845	68	9	basis	basis	NOUN
fnp-2845	68	10	of	of	ADP
fnp-2845	68	11	a	a	DET
fnp-2845	68	12	loss	loss	NOUN
fnp-2845	68	13	of	of	ADP
fnp-2845	68	14	processes	process	NOUN
fnp-2845	68	15	with	with	ADP
fnp-2845	68	16	the	the	DET
fnp-2845	68	17	remaining	remain	VERB
fnp-2845	68	18	processes	process	NOUN
fnp-2845	68	19	displaying	display	VERB
fnp-2845	68	20	significant	significant	ADJ
fnp-2845	68	21	tortuosities	tortuosity	NOUN
fnp-2845	68	22	or	or	CCONJ
fnp-2845	68	23	discontinuous	discontinuous	ADJ
fnp-2845	68	24	iba1	iba1	NOUN
fnp-2845	68	25	-	-	PUNCT
fnp-2845	68	26	immunolabelling	immunolabelling	NOUN
fnp-2845	68	27	with	with	ADP
fnp-2845	68	28	or	or	CCONJ
fnp-2845	68	29	without	without	ADP
fnp-2845	68	30	blebbing	blebbe	VERB
fnp-2845	68	31	or	or	CCONJ
fnp-2845	68	32	punctate	punctate	VERB
fnp-2845	68	33	iba1	iba1	NOUN
fnp-2845	68	34	-	-	PUNCT
fnp-2845	68	35	labelling	labelling	NOUN
fnp-2845	68	36	(	(	PUNCT
fnp-2845	68	37	previously	previously	ADV
fnp-2845	68	38	dystrophic	dystrophic	ADJ
fnp-2845	68	39	microglia	microglia	NOUN
fnp-2845	68	40	were	be	AUX
fnp-2845	68	41	subcategorised	subcategorise	VERB
fnp-2845	68	42	as	as	ADP
fnp-2845	68	43	either	either	PRON
fnp-2845	68	44	‘	'	PUNCT
fnp-2845	68	45	punctate	punctate	NOUN
fnp-2845	68	46	’	'	PUNCT
fnp-2845	68	47	or	or	CCONJ
fnp-2845	68	48	‘	'	PUNCT
fnp-2845	68	49	discontinuous	discontinuous	ADJ
fnp-2845	68	50	’	'	PUNCT
fnp-2845	68	51	to	to	PART
fnp-2845	68	52	reflect	reflect	VERB
fnp-2845	68	53	these	these	DET
fnp-2845	68	54	observations	observation	NOUN
fnp-2845	68	55	(	(	PUNCT
fnp-2845	68	56	34	34	NUM
fnp-2845	68	57	)	)	PUNCT
fnp-2845	68	58	)	)	PUNCT
fnp-2845	68	59	.	.	PUNCT
fnp-2845	69	1	a	a	DET
fnp-2845	69	2	‘	'	PUNCT
fnp-2845	69	3	cluster	cluster	NOUN
fnp-2845	69	4	of	of	ADP
fnp-2845	69	5	microglia	microglia	NOUN
fnp-2845	69	6	’	'	PUNCT
fnp-2845	69	7	was	be	AUX
fnp-2845	69	8	counted	count	VERB
fnp-2845	69	9	if	if	SCONJ
fnp-2845	69	10	three	three	NUM
fnp-2845	69	11	or	or	CCONJ
fnp-2845	69	12	more	more	ADJ
fnp-2845	69	13	soma	soma	NOUN
fnp-2845	69	14	occurred	occur	VERB
fnp-2845	69	15	within	within	ADV
fnp-2845	69	16	,	,	PUNCT
fnp-2845	69	17	or	or	CCONJ
fnp-2845	69	18	were	be	AUX
fnp-2845	69	19	touching	touch	VERB
fnp-2845	69	20	the	the	DET
fnp-2845	69	21	margins	margin	NOUN
fnp-2845	69	22	of	of	ADP
fnp-2845	69	23	,	,	PUNCT
fnp-2845	69	24	a	a	DET
fnp-2845	69	25	20	20	NUM
fnp-2845	69	26	μm2	μm2	NOUN
fnp-2845	69	27	virtual	virtual	ADJ
fnp-2845	69	28	graticule	graticule	NOUN
fnp-2845	69	29	subregion	subregion	NOUN
fnp-2845	69	30	.	.	PUNCT
fnp-2845	70	1	larger	large	ADJ
fnp-2845	70	2	clusters	cluster	NOUN
fnp-2845	70	3	were	be	AUX
fnp-2845	70	4	counted	count	VERB
fnp-2845	70	5	as	as	ADP
fnp-2845	70	6	one	one	NUM
fnp-2845	70	7	cluster	cluster	NOUN
fnp-2845	70	8	if	if	SCONJ
fnp-2845	70	9	the	the	DET
fnp-2845	70	10	graticule	graticule	NOUN
fnp-2845	70	11	subregion	subregion	NOUN
fnp-2845	70	12	could	could	AUX
fnp-2845	70	13	be	be	AUX
fnp-2845	70	14	moved	move	VERB
fnp-2845	70	15	and	and	CCONJ
fnp-2845	70	16	still	still	ADV
fnp-2845	70	17	incorporate	incorporate	VERB
fnp-2845	70	18	at	at	ADV
fnp-2845	70	19	least	least	ADV
fnp-2845	70	20	three	three	NUM
fnp-2845	70	21	somata	soma	NOUN
fnp-2845	70	22	.	.	PUNCT
fnp-2845	71	1	clusters	cluster	NOUN
fnp-2845	71	2	were	be	AUX
fnp-2845	71	3	counted	count	VERB
fnp-2845	71	4	whilst	whilst	SCONJ
fnp-2845	71	5	visualising	visualise	VERB
fnp-2845	71	6	only	only	ADV
fnp-2845	71	7	the	the	DET
fnp-2845	71	8	568	568	NUM
fnp-2845	71	9	nm	nm	NOUN
fnp-2845	71	10	(	(	PUNCT
fnp-2845	71	11	iba1	iba1	NOUN
fnp-2845	71	12	-	-	PUNCT
fnp-2845	71	13	positive	positive	ADJ
fnp-2845	71	14	)	)	PUNCT
fnp-2845	71	15	channel	channel	NOUN
fnp-2845	71	16	to	to	PART
fnp-2845	71	17	distinguish	distinguish	VERB
fnp-2845	71	18	these	these	PRON
fnp-2845	71	19	from	from	ADP
fnp-2845	71	20	individual	individual	ADJ
fnp-2845	71	21	microglia	microglia	NOUN
fnp-2845	71	22	and	and	CCONJ
fnp-2845	71	23	to	to	PART
fnp-2845	71	24	minimise	minimise	VERB
fnp-2845	71	25	potential	potential	ADJ
fnp-2845	71	26	false	false	ADJ
fnp-2845	71	27	-	-	PUNCT
fnp-2845	71	28	positive	positive	ADJ
fnp-2845	71	29	counts	count	NOUN
fnp-2845	71	30	in	in	ADP
fnp-2845	71	31	the	the	DET
fnp-2845	71	32	presence	presence	NOUN
fnp-2845	71	33	of	of	ADP
fnp-2845	71	34	either	either	DET
fnp-2845	71	35	aβor	aβor	NOUN
fnp-2845	71	36	ttau	ttau	NOUN
fnp-2845	71	37	-	-	PUNCT
fnp-2845	71	38	immunostaining	immunostaine	VERB
fnp-2845	71	39	.	.	PUNCT
fnp-2845	72	1	the	the	DET
fnp-2845	72	2	total	total	ADJ
fnp-2845	72	3	number	number	NOUN
fnp-2845	72	4	of	of	ADP
fnp-2845	72	5	microglia	microglia	NOUN
fnp-2845	72	6	counted	count	VERB
fnp-2845	72	7	per	per	ADP
fnp-2845	72	8	section	section	NOUN
fnp-2845	72	9	averaged	average	VERB
fnp-2845	72	10	519	519	NUM
fnp-2845	72	11	with	with	ADP
fnp-2845	72	12	a	a	DET
fnp-2845	72	13	coefficient	coefficient	NOUN
fnp-2845	72	14	of	of	ADP
fnp-2845	72	15	error	error	NOUN
fnp-2845	72	16	(	(	PUNCT
fnp-2845	72	17	ce	ce	PROPN
fnp-2845	72	18	)	)	PUNCT
fnp-2845	72	19	of	of	ADP
fnp-2845	72	20	≤0.2	≤0.2	ADP
fnp-2845	72	21	for	for	ADP
fnp-2845	72	22	all	all	DET
fnp-2845	72	23	counts	count	NOUN
fnp-2845	72	24	of	of	ADP
fnp-2845	72	25	morphological	morphological	ADJ
fnp-2845	72	26	subtypes	subtype	NOUN
fnp-2845	72	27	,	,	PUNCT
fnp-2845	72	28	with	with	ADP
fnp-2845	72	29	the	the	DET
fnp-2845	72	30	exception	exception	NOUN
fnp-2845	72	31	of	of	ADP
fnp-2845	72	32	microglial	microglial	ADJ
fnp-2845	72	33	clusters	cluster	NOUN
fnp-2845	72	34	(	(	PUNCT
fnp-2845	72	35	ce	ce	PROPN
fnp-2845	72	36	≤0.3	≤0.3	X
fnp-2845	72	37	)	)	PUNCT
fnp-2845	72	38	which	which	PRON
fnp-2845	72	39	were	be	AUX
fnp-2845	72	40	relatively	relatively	ADV
fnp-2845	72	41	rare	rare	ADJ
fnp-2845	72	42	and	and	CCONJ
fnp-2845	72	43	displayed	display	VERB
fnp-2845	72	44	significant	significant	ADJ
fnp-2845	72	45	variance	variance	NOUN
fnp-2845	72	46	between	between	ADP
fnp-2845	72	47	cases	case	NOUN
fnp-2845	72	48	.	.	PUNCT
fnp-2845	73	1	quantification	quantification	NOUN
fnp-2845	73	2	of	of	ADP
fnp-2845	73	3	ttau	ttau	PROPN
fnp-2845	73	4	was	be	AUX
fnp-2845	73	5	carried	carry	VERB
fnp-2845	73	6	out	out	ADP
fnp-2845	73	7	using	use	VERB
fnp-2845	73	8	an	an	DET
fnp-2845	73	9	olympus	olympus	ADJ
fnp-2845	73	10	vs120	vs120	ADJ
fnp-2845	73	11	slide	slide	NOUN
fnp-2845	73	12	scanner	scanner	NOUN
fnp-2845	73	13	at	at	ADP
fnp-2845	73	14	the	the	DET
fnp-2845	73	15	sydney	sydney	PROPN
fnp-2845	73	16	microscopy	microscopy	NOUN
fnp-2845	73	17	and	and	CCONJ
fnp-2845	73	18	microanalysis	microanalysis	NOUN
fnp-2845	73	19	,	,	PUNCT
fnp-2845	73	20	brain	brain	NOUN
fnp-2845	73	21	and	and	CCONJ
fnp-2845	73	22	mind	mind	NOUN
fnp-2845	73	23	centre	centre	NOUN
fnp-2845	73	24	,	,	PUNCT
fnp-2845	73	25	the	the	DET
fnp-2845	73	26	university	university	NOUN
fnp-2845	73	27	of	of	ADP
fnp-2845	73	28	sydney	sydney	PROPN
fnp-2845	73	29	.	.	PUNCT
fnp-2845	74	1	whole	whole	ADJ
fnp-2845	74	2	section	section	NOUN
fnp-2845	74	3	dic	dic	PROPN
fnp-2845	74	4	and	and	CCONJ
fnp-2845	74	5	fluorescence	fluorescence	ADJ
fnp-2845	74	6	overviews	overview	NOUN
fnp-2845	74	7	of	of	ADP
fnp-2845	74	8	a	a	DET
fnp-2845	74	9	single	single	ADJ
fnp-2845	74	10	section	section	NOUN
fnp-2845	74	11	from	from	ADP
fnp-2845	74	12	each	each	DET
fnp-2845	74	13	case	case	NOUN
fnp-2845	74	14	were	be	AUX
fnp-2845	74	15	generated	generate	VERB
fnp-2845	74	16	using	use	VERB
fnp-2845	74	17	a	a	DET
fnp-2845	74	18	10×	10×	NUM
fnp-2845	74	19	objective	objective	NOUN
fnp-2845	74	20	and	and	CCONJ
fnp-2845	74	21	were	be	AUX
fnp-2845	74	22	used	use	VERB
fnp-2845	74	23	to	to	PART
fnp-2845	74	24	systematically	systematically	ADV
fnp-2845	74	25	map	map	VERB
fnp-2845	74	26	out	out	ADP
fnp-2845	74	27	four	four	NUM
fnp-2845	74	28	representative	representative	ADJ
fnp-2845	74	29	500	500	NUM
fnp-2845	74	30	μm2	μm2	NOUN
fnp-2845	74	31	regions	region	NOUN
fnp-2845	74	32	of	of	ADP
fnp-2845	74	33	interest	interest	NOUN
fnp-2845	74	34	(=	(=	ADV
fnp-2845	74	35	1mm2	1mm2	NUM
fnp-2845	74	36	per	per	ADP
fnp-2845	74	37	section	section	NOUN
fnp-2845	74	38	)	)	PUNCT
fnp-2845	74	39	within	within	ADP
fnp-2845	74	40	the	the	DET
fnp-2845	74	41	mid	mid	ADJ
fnp-2845	74	42	-	-	ADJ
fnp-2845	74	43	cortical	cortical	ADJ
fnp-2845	74	44	laminae	laminae	NOUN
fnp-2845	74	45	(	(	PUNCT
fnp-2845	74	46	iii	iii	NOUN
fnp-2845	74	47	-	-	PUNCT
fnp-2845	74	48	v	v	NOUN
fnp-2845	74	49	)	)	PUNCT
fnp-2845	74	50	for	for	ADP
fnp-2845	74	51	manual	manual	ADJ
fnp-2845	74	52	counts	count	NOUN
fnp-2845	74	53	of	of	ADP
fnp-2845	74	54	nfts	nft	NOUN
fnp-2845	74	55	and	and	CCONJ
fnp-2845	74	56	for	for	ADP
fnp-2845	74	57	the	the	DET
fnp-2845	74	58	quantification	quantification	NOUN
fnp-2845	74	59	of	of	ADP
fnp-2845	74	60	ttau	ttau	ADV
fnp-2845	74	61	-	-	PUNCT
fnp-2845	74	62	positive	positive	ADJ
fnp-2845	74	63	pixels	pixel	NOUN
fnp-2845	74	64	.	.	PUNCT
fnp-2845	75	1	individual	individual	ADJ
fnp-2845	75	2	images	image	NOUN
fnp-2845	75	3	were	be	AUX
fnp-2845	75	4	captured	capture	VERB
fnp-2845	75	5	using	use	VERB
fnp-2845	75	6	a	a	DET
fnp-2845	75	7	40×/0.9	40×/0.9	NOUN
fnp-2845	75	8	na	na	NOUN
fnp-2845	75	9	objective	objective	NOUN
fnp-2845	75	10	and	and	CCONJ
fnp-2845	75	11	were	be	AUX
fnp-2845	75	12	comprised	comprise	VERB
fnp-2845	75	13	of	of	ADP
fnp-2845	75	14	seven	seven	NUM
fnp-2845	75	15	z	z	NOUN
fnp-2845	75	16	-	-	PUNCT
fnp-2845	75	17	slices	slice	NOUN
fnp-2845	75	18	with	with	ADP
fnp-2845	75	19	a	a	DET
fnp-2845	75	20	depth	depth	NOUN
fnp-2845	75	21	of	of	ADP
fnp-2845	75	22	6	6	NUM
fnp-2845	75	23	μm	μm	NOUN
fnp-2845	75	24	(	(	PUNCT
fnp-2845	75	25	z	z	NOUN
fnp-2845	75	26	-	-	PUNCT
fnp-2845	75	27	step	step	NOUN
fnp-2845	75	28	=	=	SYM
fnp-2845	75	29	1	1	NUM
fnp-2845	75	30	μm	μm	NUM
fnp-2845	75	31	)	)	PUNCT
fnp-2845	75	32	.	.	PUNCT
fnp-2845	76	1	image	image	NOUN
fnp-2845	76	2	analysis	analysis	NOUN
fnp-2845	76	3	was	be	AUX
fnp-2845	76	4	performed	perform	VERB
fnp-2845	76	5	in	in	ADP
fnp-2845	76	6	fiji	fiji	PROPN
fnp-2845	76	7	using	use	VERB
fnp-2845	76	8	manually	manually	ADV
fnp-2845	76	9	thresholded	thresholde	VERB
fnp-2845	76	10	images	image	NOUN
fnp-2845	76	11	.	.	PUNCT
fnp-2845	77	1	positive	positive	ADJ
fnp-2845	77	2	pixel	pixel	PROPN
fnp-2845	77	3	counts	count	NOUN
fnp-2845	77	4	were	be	AUX
fnp-2845	77	5	generated	generate	VERB
fnp-2845	77	6	for	for	ADP
fnp-2845	77	7	aβ	aβ	PRON
fnp-2845	77	8	and	and	CCONJ
fnp-2845	77	9	ttau	ttau	AUX
fnp-2845	77	10	staining	stain	VERB
fnp-2845	77	11	and	and	CCONJ
fnp-2845	77	12	expressed	express	VERB
fnp-2845	77	13	as	as	ADP
fnp-2845	77	14	a	a	DET
fnp-2845	77	15	percentage	percentage	NOUN
fnp-2845	77	16	of	of	ADP
fnp-2845	77	17	total	total	ADJ
fnp-2845	77	18	pixels	pixel	NOUN
fnp-2845	77	19	(	(	PUNCT
fnp-2845	77	20	%	%	INTJ
fnp-2845	77	21	aβ	aβ	NOUN
fnp-2845	77	22	and	and	CCONJ
fnp-2845	77	23	%	%	INTJ
fnp-2845	77	24	ttau	ttau	ADV
fnp-2845	77	25	respectively	respectively	ADV
fnp-2845	77	26	)	)	PUNCT
fnp-2845	77	27	.	.	PUNCT
fnp-2845	78	1	high	high	ADJ
fnp-2845	78	2	resolution	resolution	NOUN
fnp-2845	78	3	imaging	imaging	NOUN
fnp-2845	78	4	of	of	ADP
fnp-2845	78	5	all	all	DET
fnp-2845	78	6	immunolabelled	immunolabelled	ADJ
fnp-2845	78	7	sections	section	NOUN
fnp-2845	78	8	were	be	AUX
fnp-2845	78	9	carried	carry	VERB
fnp-2845	78	10	out	out	ADP
fnp-2845	78	11	using	use	VERB
fnp-2845	78	12	a	a	DET
fnp-2845	78	13	nikon	nikon	ADJ
fnp-2845	78	14	a1r	a1r	NOUN
fnp-2845	78	15	or	or	CCONJ
fnp-2845	78	16	zeiss	zeiss	VERB
fnp-2845	78	17	lsm	lsm	PROPN
fnp-2845	78	18	710	710	NUM
fnp-2845	78	19	confocal	confocal	ADJ
fnp-2845	78	20	microscope	microscope	NOUN
fnp-2845	78	21	(	(	PUNCT
fnp-2845	78	22	sydney	sydney	NOUN
fnp-2845	78	23	microscopy	microscopy	NOUN
fnp-2845	78	24	and	and	CCONJ
fnp-2845	78	25	microanalysis	microanalysis	NOUN
fnp-2845	78	26	,	,	PUNCT
fnp-2845	78	27	charles	charles	PROPN
fnp-2845	78	28	perkins	perkins	PROPN
fnp-2845	78	29	centre	centre	PROPN
fnp-2845	78	30	and	and	CCONJ
fnp-2845	78	31	brain	brain	NOUN
fnp-2845	78	32	and	and	CCONJ
fnp-2845	78	33	mind	mind	NOUN
fnp-2845	78	34	centre	centre	NOUN
fnp-2845	78	35	,	,	PUNCT
fnp-2845	78	36	the	the	DET
fnp-2845	78	37	university	university	NOUN
fnp-2845	78	38	of	of	ADP
fnp-2845	78	39	sydney	sydney	PROPN
fnp-2845	78	40	)	)	PUNCT
fnp-2845	78	41	.	.	PUNCT
fnp-2845	79	1	features	feature	NOUN
fnp-2845	79	2	were	be	AUX
fnp-2845	79	3	imaged	image	VERB
fnp-2845	79	4	with	with	ADP
fnp-2845	79	5	either	either	CCONJ
fnp-2845	79	6	a	a	DET
fnp-2845	79	7	40×/0.95	40×/0.95	NUM
fnp-2845	79	8	na	na	NOUN
fnp-2845	79	9	or	or	CCONJ
fnp-2845	79	10	100×/1.4	100×/1.4	NUM
fnp-2845	79	11	na	na	NOUN
fnp-2845	79	12	objective	objective	NOUN
fnp-2845	79	13	and	and	CCONJ
fnp-2845	79	14	shown	show	VERB
fnp-2845	79	15	as	as	ADP
fnp-2845	79	16	maximum	maximum	ADJ
fnp-2845	79	17	intensity	intensity	NOUN
fnp-2845	79	18	projections	projection	NOUN
fnp-2845	79	19	.	.	PUNCT
fnp-2845	80	1	nissl	nissl	PROPN
fnp-2845	80	2	staining	stain	VERB
fnp-2845	80	3	nissl	nissl	ADJ
fnp-2845	80	4	stains	stain	NOUN
fnp-2845	80	5	of	of	ADP
fnp-2845	80	6	free	free	ADV
fnp-2845	80	7	-	-	PUNCT
fnp-2845	80	8	floating	float	VERB
fnp-2845	80	9	45	45	NUM
fnp-2845	80	10	μm	μm	NUM
fnp-2845	80	11	thick	thick	ADJ
fnp-2845	80	12	formalin	formalin	NOUN
fnp-2845	80	13	-	-	PUNCT
fnp-2845	80	14	fixed	fix	VERB
fnp-2845	80	15	sections	section	NOUN
fnp-2845	80	16	were	be	AUX
fnp-2845	80	17	performed	perform	VERB
fnp-2845	80	18	for	for	ADP
fnp-2845	80	19	the	the	DET
fnp-2845	80	20	measurement	measurement	NOUN
fnp-2845	80	21	of	of	ADP
fnp-2845	80	22	cortical	cortical	ADJ
fnp-2845	80	23	thickness	thickness	NOUN
fnp-2845	80	24	and	and	CCONJ
fnp-2845	80	25	neuronal	neuronal	ADJ
fnp-2845	80	26	counts	count	NOUN
fnp-2845	80	27	.	.	PUNCT
fnp-2845	81	1	sections	section	NOUN
fnp-2845	81	2	were	be	AUX
fnp-2845	81	3	incubated	incubate	VERB
fnp-2845	81	4	in	in	ADP
fnp-2845	81	5	0.1	0.1	NUM
fnp-2845	81	6	%	%	NOUN
fnp-2845	81	7	cresyl	cresyl	NOUN
fnp-2845	81	8	violet	violet	NOUN
fnp-2845	81	9	acetate	acetate	NOUN
fnp-2845	81	10	(	(	PUNCT
fnp-2845	81	11	0.02	0.02	NUM
fnp-2845	81	12	%	%	NOUN
fnp-2845	81	13	glacial	glacial	ADJ
fnp-2845	81	14	acetic	acetic	ADJ
fnp-2845	81	15	acid	acid	NOUN
fnp-2845	81	16	;	;	PUNCT
fnp-2845	81	17	added	add	VERB
fnp-2845	81	18	immediately	immediately	ADV
fnp-2845	81	19	before	before	ADP
fnp-2845	81	20	use	use	NOUN
fnp-2845	81	21	)	)	PUNCT
fnp-2845	81	22	for	for	ADP
fnp-2845	81	23	15	15	NUM
fnp-2845	81	24	minutes	minute	NOUN
fnp-2845	81	25	at	at	ADP
fnp-2845	81	26	60	60	NUM
fnp-2845	81	27	°	°	NOUN
fnp-2845	81	28	c	c	NOUN
fnp-2845	81	29	.	.	PUNCT
fnp-2845	82	1	differentiation	differentiation	NOUN
fnp-2845	82	2	was	be	AUX
fnp-2845	82	3	achieved	achieve	VERB
fnp-2845	82	4	by	by	ADP
fnp-2845	82	5	sequentially	sequentially	ADV
fnp-2845	82	6	washing	washing	NOUN
fnp-2845	82	7	sections	section	NOUN
fnp-2845	82	8	for	for	ADP
fnp-2845	82	9	three	three	NUM
fnp-2845	82	10	minutes	minute	NOUN
fnp-2845	82	11	in	in	ADP
fnp-2845	82	12	70	70	NUM
fnp-2845	82	13	%	%	NOUN
fnp-2845	82	14	and	and	CCONJ
fnp-2845	82	15	95	95	NUM
fnp-2845	82	16	%	%	NOUN
fnp-2845	82	17	ethanol	ethanol	NOUN
fnp-2845	82	18	.	.	PUNCT
fnp-2845	83	1	the	the	DET
fnp-2845	83	2	final	final	ADJ
fnp-2845	83	3	level	level	NOUN
fnp-2845	83	4	of	of	ADP
fnp-2845	83	5	staining	stain	VERB
fnp-2845	83	6	was	be	AUX
fnp-2845	83	7	adjusted	adjust	VERB
fnp-2845	83	8	by	by	ADP
fnp-2845	83	9	briefly	briefly	NOUN
fnp-2845	83	10	dipping	dipping	NOUN
fnp-2845	83	11	sections	section	NOUN
fnp-2845	83	12	in	in	ADP
fnp-2845	83	13	100	100	NUM
fnp-2845	83	14	%	%	NOUN
fnp-2845	83	15	ethanol	ethanol	NOUN
fnp-2845	83	16	and	and	CCONJ
fnp-2845	83	17	confirmed	confirm	VERB
fnp-2845	83	18	by	by	ADP
fnp-2845	83	19	light	light	ADJ
fnp-2845	83	20	microscopy	microscopy	NOUN
fnp-2845	83	21	before	before	ADP
fnp-2845	83	22	clearing	clear	VERB
fnp-2845	83	23	in	in	ADP
fnp-2845	83	24	xylene	xylene	NOUN
fnp-2845	83	25	for	for	ADP
fnp-2845	83	26	ten	ten	NUM
fnp-2845	83	27	minutes	minute	NOUN
fnp-2845	83	28	and	and	CCONJ
fnp-2845	83	29	mounting	mount	VERB
fnp-2845	83	30	in	in	ADP
fnp-2845	83	31	dpx	dpx	PROPN
fnp-2845	83	32	.	.	PUNCT
fnp-2845	84	1	cortical	cortical	ADJ
fnp-2845	84	2	thickness	thickness	NOUN
fnp-2845	84	3	measurements	measurement	NOUN
fnp-2845	84	4	and	and	CCONJ
fnp-2845	84	5	neuronal	neuronal	ADJ
fnp-2845	84	6	counts	count	NOUN
fnp-2845	84	7	were	be	AUX
fnp-2845	84	8	performed	perform	VERB
fnp-2845	84	9	on	on	ADP
fnp-2845	84	10	three	three	NUM
fnp-2845	84	11	cortical	cortical	ADJ
fnp-2845	84	12	strips	strip	NOUN
fnp-2845	84	13	from	from	ADP
fnp-2845	84	14	one	one	NUM
fnp-2845	84	15	section	section	NOUN
fnp-2845	84	16	per	per	ADP
fnp-2845	84	17	individual	individual	NOUN
fnp-2845	84	18	using	use	VERB
fnp-2845	84	19	an	an	DET
fnp-2845	84	20	eyepiece	eyepiece	NOUN
fnp-2845	84	21	graticule	graticule	NOUN
fnp-2845	84	22	on	on	ADP
fnp-2845	84	23	an	an	DET
fnp-2845	84	24	olympus	olympus	PROPN
fnp-2845	84	25	bx50	bx50	PROPN
fnp-2845	84	26	microscope	microscope	NOUN
fnp-2845	84	27	using	use	VERB
fnp-2845	84	28	a	a	DET
fnp-2845	84	29	20×/0.75	20×/0.75	NUM
fnp-2845	84	30	na	na	ADP
fnp-2845	84	31	objective	objective	NOUN
fnp-2845	84	32	.	.	PUNCT
fnp-2845	85	1	a	a	DET
fnp-2845	85	2	height	height	NOUN
fnp-2845	85	3	measure	measure	NOUN
fnp-2845	85	4	of	of	ADP
fnp-2845	85	5	45	45	NUM
fnp-2845	85	6	μm	μm	NOUN
fnp-2845	85	7	was	be	AUX
fnp-2845	85	8	used	use	VERB
fnp-2845	85	9	in	in	ADP
fnp-2845	85	10	determining	determine	VERB
fnp-2845	85	11	density	density	NOUN
fnp-2845	85	12	estimates	estimate	NOUN
fnp-2845	85	13	to	to	PART
fnp-2845	85	14	eliminate	eliminate	VERB
fnp-2845	85	15	artefactual	artefactual	ADJ
fnp-2845	85	16	tissue	tissue	NOUN
fnp-2845	85	17	shrinkage	shrinkage	NOUN
fnp-2845	85	18	during	during	ADP
fnp-2845	85	19	staining	stain	VERB
fnp-2845	85	20	;	;	PUNCT
fnp-2845	85	21	with	with	SCONJ
fnp-2845	85	22	the	the	DET
fnp-2845	85	23	microtome	microtome	NOUN
fnp-2845	85	24	accuracy	accuracy	NOUN
fnp-2845	85	25	to	to	PART
fnp-2845	85	26	cut	cut	VERB
fnp-2845	85	27	precise	precise	ADJ
fnp-2845	85	28	sections	section	NOUN
fnp-2845	85	29	having	having	AUX
fnp-2845	85	30	been	be	AUX
fnp-2845	85	31	previously	previously	ADV
fnp-2845	85	32	validated	validate	VERB
fnp-2845	85	33	(	(	PUNCT
fnp-2845	85	34	37	37	NUM
fnp-2845	85	35	)	)	PUNCT
fnp-2845	85	36	.	.	PUNCT
fnp-2845	86	1	ces	ce	NOUN
fnp-2845	86	2	using	use	VERB
fnp-2845	86	3	the	the	DET
fnp-2845	86	4	modified	modified	ADJ
fnp-2845	86	5	disector	disector	NOUN
fnp-2845	86	6	technique	technique	NOUN
fnp-2845	86	7	outlined	outline	VERB
fnp-2845	86	8	above	above	ADV
fnp-2845	86	9	were	be	AUX
fnp-2845	86	10	<	<	X
fnp-2845	86	11	0.1	0.1	NUM
fnp-2845	86	12	for	for	ADP
fnp-2845	86	13	cortical	cortical	ADJ
fnp-2845	86	14	thickness	thickness	NOUN
fnp-2845	86	15	and	and	CCONJ
fnp-2845	86	16	<	<	X
fnp-2845	86	17	0.15	0.15	NUM
fnp-2845	86	18	for	for	ADP
fnp-2845	86	19	the	the	DET
fnp-2845	86	20	density	density	NOUN
fnp-2845	86	21	of	of	ADP
fnp-2845	86	22	betz	betz	PROPN
fnp-2845	86	23	cells	cell	NOUN
fnp-2845	86	24	and	and	CCONJ
fnp-2845	86	25	total	total	ADJ
fnp-2845	86	26	neurons	neuron	NOUN
fnp-2845	86	27	.	.	PUNCT
fnp-2845	87	1	statistical	statistical	ADJ
fnp-2845	87	2	analyses	analysis	NOUN
fnp-2845	87	3	the	the	DET
fnp-2845	87	4	normality	normality	NOUN
fnp-2845	87	5	of	of	ADP
fnp-2845	87	6	data	datum	NOUN
fnp-2845	87	7	was	be	AUX
fnp-2845	87	8	tested	test	VERB
fnp-2845	87	9	using	use	VERB
fnp-2845	87	10	the	the	DET
fnp-2845	87	11	shapiro	shapiro	PROPN
fnp-2845	87	12	-	-	PUNCT
fnp-2845	87	13	wilk	wilk	NOUN
fnp-2845	87	14	test	test	NOUN
fnp-2845	87	15	.	.	PUNCT
fnp-2845	88	1	equality	equality	NOUN
fnp-2845	88	2	of	of	ADP
fnp-2845	88	3	variances	variance	NOUN
fnp-2845	88	4	was	be	AUX
fnp-2845	88	5	tested	test	VERB
fnp-2845	88	6	using	use	VERB
fnp-2845	88	7	brown	brown	ADJ
fnp-2845	88	8	-	-	PUNCT
fnp-2845	88	9	forsythe	forsythe	PROPN
fnp-2845	88	10	test	test	NOUN
fnp-2845	88	11	.	.	PUNCT
fnp-2845	89	1	group	group	NOUN
fnp-2845	89	2	differences	difference	NOUN
fnp-2845	89	3	were	be	AUX
fnp-2845	89	4	investigated	investigate	VERB
fnp-2845	89	5	by	by	ADP
fnp-2845	89	6	either	either	DET
fnp-2845	89	7	welch	welch	PROPN
fnp-2845	89	8	’s	’s	PART
fnp-2845	89	9	analysis	analysis	NOUN
fnp-2845	89	10	of	of	ADP
fnp-2845	89	11	variance	variance	NOUN
fnp-2845	89	12	or	or	CCONJ
fnp-2845	89	13	kruskal	kruskal	PROPN
fnp-2845	89	14	-	-	PUNCT
fnp-2845	89	15	wallis	wallis	PROPN
fnp-2845	89	16	test	test	NOUN
fnp-2845	89	17	for	for	ADP
fnp-2845	89	18	non	non	ADJ
fnp-2845	89	19	-	-	ADJ
fnp-2845	89	20	gaussian	gaussian	ADJ
fnp-2845	89	21	distributions	distribution	NOUN
fnp-2845	89	22	,	,	PUNCT
fnp-2845	89	23	with	with	ADP
fnp-2845	89	24	either	either	PRON
fnp-2845	89	25	games	game	NOUN
fnp-2845	89	26	-	-	PUNCT
fnp-2845	89	27	howell	howell	PROPN
fnp-2845	89	28	or	or	CCONJ
fnp-2845	89	29	dunn	dunn	PROPN
fnp-2845	89	30	’s	’s	PART
fnp-2845	89	31	test	test	NOUN
fnp-2845	89	32	,	,	PUNCT
fnp-2845	89	33	respectively	respectively	ADV
fnp-2845	89	34	,	,	PUNCT
fnp-2845	89	35	for	for	ADP
fnp-2845	89	36	pairwise	pairwise	NOUN
fnp-2845	89	37	comparisons	comparison	NOUN
fnp-2845	89	38	.	.	PUNCT
fnp-2845	90	1	regional	regional	ADJ
fnp-2845	90	2	differences	difference	NOUN
fnp-2845	90	3	to	to	ADP
fnp-2845	90	4	the	the	DET
fnp-2845	90	5	previously	previously	ADV
fnp-2845	90	6	reported	report	VERB
fnp-2845	90	7	itc	itc	PROPN
fnp-2845	90	8	(	(	PUNCT
fnp-2845	90	9	26	26	NUM
fnp-2845	90	10	)	)	PUNCT
fnp-2845	90	11	were	be	AUX
fnp-2845	90	12	investigated	investigate	VERB
fnp-2845	90	13	by	by	ADP
fnp-2845	90	14	either	either	DET
fnp-2845	90	15	welch	welch	PROPN
fnp-2845	90	16	’s	’s	PART
fnp-2845	90	17	t	t	PROPN
fnp-2845	90	18	test	test	NOUN
fnp-2845	90	19	or	or	CCONJ
fnp-2845	90	20	wilcoxon	wilcoxon	CCONJ
fnp-2845	90	21	rank	rank	NOUN
fnp-2845	90	22	-	-	PUNCT
fnp-2845	90	23	sum	sum	NOUN
fnp-2845	90	24	test	test	NOUN
fnp-2845	90	25	for	for	ADP
fnp-2845	90	26	non	non	ADJ
fnp-2845	90	27	-	-	ADJ
fnp-2845	90	28	gaussian	gaussian	ADJ
fnp-2845	90	29	distributions	distribution	NOUN
fnp-2845	90	30	.	.	PUNCT
fnp-2845	91	1	the	the	DET
fnp-2845	91	2	pearson	pearson	PROPN
fnp-2845	91	3	correlation	correlation	NOUN
fnp-2845	91	4	coefficient	coefficient	NOUN
fnp-2845	91	5	(	(	PUNCT
fnp-2845	91	6	r	r	NOUN
fnp-2845	91	7	)	)	PUNCT
fnp-2845	91	8	and	and	CCONJ
fnp-2845	91	9	coefficient	coefficient	NOUN
fnp-2845	91	10	of	of	ADP
fnp-2845	91	11	determination	determination	NOUN
fnp-2845	91	12	(	(	PUNCT
fnp-2845	91	13	r2	r2	PROPN
fnp-2845	91	14	)	)	PUNCT
fnp-2845	91	15	,	,	PUNCT
fnp-2845	91	16	or	or	CCONJ
fnp-2845	91	17	spearman	spearman	NOUN
fnp-2845	91	18	rho	rho	PROPN
fnp-2845	91	19	(	(	PUNCT
fnp-2845	91	20	ρ	ρ	PROPN
fnp-2845	91	21	)	)	PUNCT
fnp-2845	91	22	for	for	ADP
fnp-2845	91	23	non	non	ADJ
fnp-2845	91	24	-	-	ADJ
fnp-2845	91	25	gaussian	gaussian	ADJ
fnp-2845	91	26	distributions	distribution	NOUN
fnp-2845	91	27	,	,	PUNCT
fnp-2845	91	28	were	be	AUX
fnp-2845	91	29	calculated	calculate	VERB
fnp-2845	91	30	for	for	ADP
fnp-2845	91	31	univariate	univariate	ADJ
fnp-2845	91	32	correlations	correlation	NOUN
fnp-2845	91	33	to	to	PART
fnp-2845	91	34	investigate	investigate	VERB
fnp-2845	91	35	relationships	relationship	NOUN
fnp-2845	91	36	between	between	ADP
fnp-2845	91	37	ad	ad	NOUN
fnp-2845	91	38	-	-	PUNCT
fnp-2845	91	39	type	type	NOUN
fnp-2845	91	40	pathology	pathology	NOUN
fnp-2845	91	41	,	,	PUNCT
fnp-2845	91	42	microglial	microglial	ADJ
fnp-2845	91	43	morphologies	morphology	NOUN
fnp-2845	91	44	,	,	PUNCT
fnp-2845	91	45	and	and	CCONJ
fnp-2845	91	46	apoe	apoe	ADJ
fnp-2845	91	47	ε4	ε4	PROPN
fnp-2845	91	48	status	status	NOUN
fnp-2845	91	49	.	.	PUNCT
fnp-2845	92	1	stepwise	stepwise	PROPN
fnp-2845	92	2	regression	regression	NOUN
fnp-2845	92	3	models	model	NOUN
fnp-2845	92	4	which	which	PRON
fnp-2845	92	5	included	include	VERB
fnp-2845	92	6	age	age	NOUN
fnp-2845	92	7	,	,	PUNCT
fnp-2845	92	8	sex	sex	NOUN
fnp-2845	92	9	,	,	PUNCT
fnp-2845	92	10	brain	brain	NOUN
fnp-2845	92	11	ph	ph	VERB
fnp-2845	92	12	,	,	PUNCT
fnp-2845	92	13	post	post	ADJ
fnp-2845	92	14	-	-	ADJ
fnp-2845	92	15	mortem	mortem	ADJ
fnp-2845	92	16	interval	interval	NOUN
fnp-2845	92	17	,	,	PUNCT
fnp-2845	92	18	and	and	CCONJ
fnp-2845	92	19	fixation	fixation	NOUN
fnp-2845	92	20	period	period	NOUN
fnp-2845	92	21	were	be	AUX
fnp-2845	92	22	performed	perform	VERB
fnp-2845	92	23	to	to	PART
fnp-2845	92	24	exclude	exclude	VERB
fnp-2845	92	25	effects	effect	NOUN
fnp-2845	92	26	of	of	ADP
fnp-2845	92	27	potential	potential	ADJ
fnp-2845	92	28	confounders	confounder	NOUN
fnp-2845	92	29	.	.	PUNCT
fnp-2845	93	1	a	a	DET
fnp-2845	93	2	p	p	NOUN
fnp-2845	93	3	-	-	PUNCT
fnp-2845	93	4	value	value	NOUN
fnp-2845	93	5	<	<	NOUN
fnp-2845	93	6	0.05	0.05	NUM
fnp-2845	93	7	was	be	AUX
fnp-2845	93	8	considered	consider	VERB
fnp-2845	93	9	statistically	statistically	ADV
fnp-2845	93	10	significant	significant	ADJ
fnp-2845	93	11	.	.	PUNCT
fnp-2845	94	1	all	all	DET
fnp-2845	94	2	statistical	statistical	ADJ
fnp-2845	94	3	analyses	analysis	NOUN
fnp-2845	94	4	were	be	AUX
fnp-2845	94	5	performed	perform	VERB
fnp-2845	94	6	using	use	VERB
fnp-2845	94	7	jmp	jmp	PROPN
fnp-2845	94	8	pro	pro	X
fnp-2845	94	9	14	14	NUM
fnp-2845	94	10	(	(	PUNCT
fnp-2845	94	11	sas	sas	PROPN
fnp-2845	94	12	institute	institute	PROPN
fnp-2845	94	13	inc	inc	PROPN
fnp-2845	94	14	)	)	PUNCT
fnp-2845	94	15	.	.	PUNCT
fnp-2845	95	1	graphs	graph	NOUN
fnp-2845	95	2	were	be	AUX
fnp-2845	95	3	produced	produce	VERB
fnp-2845	95	4	using	use	VERB
fnp-2845	95	5	microsoft	microsoft	PROPN
fnp-2845	95	6	excel	excel	PROPN
fnp-2845	95	7	.	.	PUNCT
fnp-2845	96	1	results	result	VERB
fnp-2845	96	2	the	the	DET
fnp-2845	96	3	alzheimer	alzheimer	PROPN
fnp-2845	96	4	’s	’s	PART
fnp-2845	96	5	disease	disease	NOUN
fnp-2845	96	6	primary	primary	ADJ
fnp-2845	96	7	motor	motor	NOUN
fnp-2845	96	8	cortex	cortex	NOUN
fnp-2845	96	9	exhibits	exhibit	VERB
fnp-2845	96	10	mild	mild	ADJ
fnp-2845	96	11	tau	tau	NOUN
fnp-2845	96	12	and	and	CCONJ
fnp-2845	96	13	β	β	NOUN
fnp-2845	96	14	-	-	ADJ
fnp-2845	96	15	amyloid	amyloid	NOUN
fnp-2845	96	16	deposition	deposition	NOUN
fnp-2845	96	17	but	but	CCONJ
fnp-2845	96	18	no	no	DET
fnp-2845	96	19	evidence	evidence	NOUN
fnp-2845	96	20	of	of	ADP
fnp-2845	96	21	neurodegeneration	neurodegeneration	NOUN
fnp-2845	96	22	this	this	DET
fnp-2845	96	23	study	study	NOUN
fnp-2845	96	24	involved	involve	VERB
fnp-2845	96	25	23	23	NUM
fnp-2845	96	26	autopsy	autopsy	ADJ
fnp-2845	96	27	cases	case	NOUN
fnp-2845	96	28	that	that	PRON
fnp-2845	96	29	had	have	AUX
fnp-2845	96	30	previously	previously	ADV
fnp-2845	96	31	been	be	AUX
fnp-2845	96	32	clinicopathologically	clinicopathologically	ADV
fnp-2845	96	33	characterised	characterise	VERB
fnp-2845	96	34	as	as	ADP
fnp-2845	96	35	‘	'	PUNCT
fnp-2845	96	36	probable	probable	ADJ
fnp-2845	96	37	ad	ad	NOUN
fnp-2845	96	38	’	'	PUNCT
fnp-2845	96	39	or	or	CCONJ
fnp-2845	96	40	controls	control	NOUN
fnp-2845	96	41	based	base	VERB
fnp-2845	96	42	on	on	ADP
fnp-2845	96	43	abc	abc	PROPN
fnp-2845	96	44	score	score	NOUN
fnp-2845	96	45	and	and	CCONJ
fnp-2845	96	46	clinical	clinical	ADJ
fnp-2845	96	47	dementia	dementia	NOUN
fnp-2845	96	48	rating	rating	NOUN
fnp-2845	96	49	(	(	PUNCT
fnp-2845	96	50	table	table	NOUN
fnp-2845	96	51	1	1	NUM
fnp-2845	96	52	)	)	PUNCT
fnp-2845	96	53	(	(	PUNCT
fnp-2845	96	54	39	39	NUM
fnp-2845	96	55	)	)	PUNCT
fnp-2845	96	56	.	.	PUNCT
fnp-2845	97	1	ad	ad	NOUN
fnp-2845	97	2	cases	case	NOUN
fnp-2845	97	3	(	(	PUNCT
fnp-2845	97	4	n=8	n=8	NUM
fnp-2845	97	5	)	)	PUNCT
fnp-2845	97	6	included	include	VERB
fnp-2845	97	7	individuals	individual	NOUN
fnp-2845	97	8	with	with	ADP
fnp-2845	97	9	an	an	DET
fnp-2845	97	10	intermediate	intermediate	ADJ
fnp-2845	97	11	–	–	PUNCT
fnp-2845	97	12	high	high	ADJ
fnp-2845	97	13	likelihood	likelihood	NOUN
fnp-2845	97	14	of	of	ADP
fnp-2845	97	15	ad	ad	NOUN
fnp-2845	97	16	dementia	dementia	NOUN
fnp-2845	97	17	following	follow	VERB
fnp-2845	97	18	routine	routine	ADJ
fnp-2845	97	19	neuropathological	neuropathological	ADJ
fnp-2845	97	20	diagnostic	diagnostic	ADJ
fnp-2845	97	21	testing	testing	NOUN
fnp-2845	97	22	(	(	PUNCT
fnp-2845	97	23	38	38	NUM
fnp-2845	97	24	)	)	PUNCT
fnp-2845	97	25	and	and	CCONJ
fnp-2845	97	26	who	who	PRON
fnp-2845	97	27	presented	present	VERB
fnp-2845	97	28	with	with	ADP
fnp-2845	97	29	typical	typical	ADJ
fnp-2845	97	30	ad	ad	NOUN
fnp-2845	97	31	dementia	dementia	NOUN
fnp-2845	97	32	prior	prior	ADV
fnp-2845	97	33	to	to	ADP
fnp-2845	97	34	death	death	NOUN
fnp-2845	97	35	.	.	PUNCT
fnp-2845	98	1	‘	'	PUNCT
fnp-2845	98	2	high	high	ADJ
fnp-2845	98	3	pathology	pathology	NOUN
fnp-2845	98	4	controls	control	NOUN
fnp-2845	98	5	’	'	PUNCT
fnp-2845	98	6	(	(	PUNCT
fnp-2845	98	7	hpc	hpc	PROPN
fnp-2845	98	8	)	)	PUNCT
fnp-2845	98	9	(	(	PUNCT
fnp-2845	98	10	n=5	n=5	X
fnp-2845	98	11	)	)	PUNCT
fnp-2845	98	12	were	be	AUX
fnp-2845	98	13	grouped	group	VERB
fnp-2845	98	14	as	as	ADV
fnp-2845	98	15	such	such	ADJ
fnp-2845	98	16	on	on	ADP
fnp-2845	98	17	the	the	DET
fnp-2845	98	18	basis	basis	NOUN
fnp-2845	98	19	of	of	ADP
fnp-2845	98	20	no	no	DET
fnp-2845	98	21	cognitive	cognitive	ADJ
fnp-2845	98	22	impairment	impairment	NOUN
fnp-2845	98	23	but	but	CCONJ
fnp-2845	98	24	satisfied	satisfy	VERB
fnp-2845	98	25	a	a	DET
fnp-2845	98	26	diagnosis	diagnosis	NOUN
fnp-2845	98	27	of	of	ADP
fnp-2845	98	28	intermediate	intermediate	ADJ
fnp-2845	98	29	ad	ad	NOUN
fnp-2845	98	30	likelihood	likelihood	NOUN
fnp-2845	98	31	on	on	ADP
fnp-2845	98	32	post	post	ADJ
fnp-2845	98	33	-	-	ADJ
fnp-2845	98	34	mortem	mortem	ADJ
fnp-2845	98	35	examination	examination	NOUN
fnp-2845	98	36	.	.	PUNCT
fnp-2845	99	1	controls	control	NOUN
fnp-2845	99	2	(	(	PUNCT
fnp-2845	99	3	n=10	n=10	NOUN
fnp-2845	99	4	)	)	PUNCT
fnp-2845	99	5	included	include	VERB
fnp-2845	99	6	individuals	individual	NOUN
fnp-2845	99	7	with	with	ADP
fnp-2845	99	8	a	a	DET
fnp-2845	99	9	range	range	NOUN
fnp-2845	99	10	of	of	ADP
fnp-2845	99	11	abc	abc	PROPN
fnp-2845	99	12	scores	score	NOUN
fnp-2845	99	13	(	(	PUNCT
fnp-2845	99	14	a0–3	a0–3	PROPN
fnp-2845	99	15	;	;	PUNCT
fnp-2845	99	16	b0–2	b0–2	X
fnp-2845	99	17	;	;	PUNCT
fnp-2845	99	18	c0–3	c0–3	NOUN
fnp-2845	99	19	)	)	PUNCT
fnp-2845	99	20	,	,	PUNCT
fnp-2845	99	21	though	though	SCONJ
fnp-2845	99	22	only	only	ADV
fnp-2845	99	23	satisfying	satisfy	VERB
fnp-2845	99	24	a	a	DET
fnp-2845	99	25	‘	'	PUNCT
fnp-2845	99	26	not	not	PART
fnp-2845	99	27	’	'	PUNCT
fnp-2845	99	28	or	or	CCONJ
fnp-2845	99	29	‘	'	PUNCT
fnp-2845	99	30	low	low	ADJ
fnp-2845	99	31	’	'	PUNCT
fnp-2845	99	32	outcome	outcome	NOUN
fnp-2845	99	33	after	after	ADP
fnp-2845	99	34	diagnostic	diagnostic	ADJ
fnp-2845	99	35	testing	testing	NOUN
fnp-2845	99	36	.	.	PUNCT
fnp-2845	100	1	there	there	PRON
fnp-2845	100	2	was	be	VERB
fnp-2845	100	3	no	no	DET
fnp-2845	100	4	cortical	cortical	ADJ
fnp-2845	100	5	atrophy	atrophy	NOUN
fnp-2845	100	6	(	(	PUNCT
fnp-2845	100	7	fig	fig	NOUN
fnp-2845	100	8	.	.	PUNCT
fnp-2845	101	1	1a	1a	NOUN
fnp-2845	101	2	)	)	PUNCT
fnp-2845	101	3	or	or	CCONJ
fnp-2845	101	4	neuronal	neuronal	ADJ
fnp-2845	101	5	loss	loss	NOUN
fnp-2845	101	6	(	(	PUNCT
fnp-2845	101	7	fig	fig	NOUN
fnp-2845	101	8	.	.	PUNCT
fnp-2845	101	9	1b	1b	NUM
fnp-2845	101	10	)	)	PUNCT
fnp-2845	101	11	,	,	PUNCT
fnp-2845	101	12	including	include	VERB
fnp-2845	101	13	the	the	DET
fnp-2845	101	14	prominent	prominent	ADJ
fnp-2845	101	15	layer	layer	NOUN
fnp-2845	101	16	vb	vb	ADP
fnp-2845	101	17	betz	betz	PROPN
fnp-2845	101	18	cells	cell	NOUN
fnp-2845	101	19	(	(	PUNCT
fnp-2845	101	20	fig	fig	NOUN
fnp-2845	101	21	.	.	PUNCT
fnp-2845	102	1	1c	1c	NOUN
fnp-2845	102	2	)	)	PUNCT
fnp-2845	102	3	,	,	PUNCT
fnp-2845	102	4	in	in	ADP
fnp-2845	102	5	the	the	DET
fnp-2845	102	6	pmc	pmc	NOUN
fnp-2845	102	7	of	of	ADP
fnp-2845	102	8	ad	ad	NOUN
fnp-2845	102	9	cases	case	NOUN
fnp-2845	102	10	or	or	CCONJ
fnp-2845	102	11	hpcs	hpc	NOUN
fnp-2845	102	12	compared	compare	VERB
fnp-2845	102	13	with	with	ADP
fnp-2845	102	14	controls	control	NOUN
fnp-2845	102	15	.	.	PUNCT
fnp-2845	103	1	following	follow	VERB
fnp-2845	103	2	a	a	DET
fnp-2845	103	3	positive	positive	ADJ
fnp-2845	103	4	pixel	pixel	NOUN
fnp-2845	103	5	analysis	analysis	NOUN
fnp-2845	103	6	,	,	PUNCT
fnp-2845	103	7	grey	grey	NOUN
fnp-2845	103	8	matter	matter	NOUN
fnp-2845	103	9	aβ	aβ	NUM
fnp-2845	103	10	areal	areal	NOUN
fnp-2845	103	11	fraction	fraction	NOUN
fnp-2845	103	12	(	(	PUNCT
fnp-2845	103	13	%	%	INTJ
fnp-2845	103	14	aβ	aβ	NOUN
fnp-2845	103	15	)	)	PUNCT
fnp-2845	103	16	was	be	AUX
fnp-2845	103	17	higher	high	ADJ
fnp-2845	103	18	in	in	ADP
fnp-2845	103	19	the	the	DET
fnp-2845	103	20	pmc	pmc	NOUN
fnp-2845	103	21	of	of	ADP
fnp-2845	103	22	ad	ad	NOUN
fnp-2845	103	23	cases	case	NOUN
fnp-2845	103	24	compared	compare	VERB
fnp-2845	103	25	to	to	ADP
fnp-2845	103	26	controls	control	NOUN
fnp-2845	103	27	(	(	PUNCT
fnp-2845	103	28	p	p	X
fnp-2845	103	29	=	=	NOUN
fnp-2845	103	30	0.0005	0.0005	NUM
fnp-2845	103	31	)	)	PUNCT
fnp-2845	103	32	,	,	PUNCT
fnp-2845	103	33	but	but	CCONJ
fnp-2845	103	34	not	not	PART
fnp-2845	103	35	hpcs	hpc	NOUN
fnp-2845	103	36	(	(	PUNCT
fnp-2845	103	37	p	p	X
fnp-2845	103	38	=	=	NOUN
fnp-2845	103	39	0.07	0.07	NUM
fnp-2845	103	40	)	)	PUNCT
fnp-2845	103	41	.	.	PUNCT
fnp-2845	104	1	the	the	DET
fnp-2845	104	2	density	density	NOUN
fnp-2845	104	3	of	of	ADP
fnp-2845	104	4	total	total	ADJ
fnp-2845	104	5	aβ	aβ	NOUN
fnp-2845	104	6	plaques	plaque	NOUN
fnp-2845	104	7	,	,	PUNCT
fnp-2845	104	8	fibrillar	fibrillar	ADJ
fnp-2845	104	9	,	,	PUNCT
fnp-2845	104	10	and	and	CCONJ
fnp-2845	104	11	dense	dense	ADV
fnp-2845	104	12	-	-	PUNCT
fnp-2845	104	13	cored	core	VERB
fnp-2845	104	14	plaques	plaque	NOUN
fnp-2845	104	15	was	be	AUX
fnp-2845	104	16	also	also	ADV
fnp-2845	104	17	significantly	significantly	ADV
fnp-2845	104	18	higher	high	ADJ
fnp-2845	104	19	in	in	ADP
fnp-2845	104	20	ad	ad	NOUN
fnp-2845	104	21	cases	case	NOUN
fnp-2845	104	22	compared	compare	VERB
fnp-2845	104	23	to	to	ADP
fnp-2845	104	24	controls	control	NOUN
fnp-2845	104	25	(	(	PUNCT
fnp-2845	104	26	totalp	totalp	NOUN
fnp-2845	104	27	=	=	SYM
fnp-2845	104	28	0.003	0.003	NUM
fnp-2845	104	29	;	;	PUNCT
fnp-2845	104	30	fibrillarp	fibrillarp	NOUN
fnp-2845	104	31	=	=	SYM
fnp-2845	104	32	0.002	0.002	NUM
fnp-2845	104	33	;	;	PUNCT
fnp-2845	104	34	dense	dense	ADJ
fnp-2845	104	35	-	-	PUNCT
fnp-2845	104	36	coredp	coredp	ADJ
fnp-2845	104	37	=	=	NOUN
fnp-2845	104	38	0.004	0.004	NUM
fnp-2845	104	39	)	)	PUNCT
fnp-2845	104	40	but	but	CCONJ
fnp-2845	104	41	not	not	PART
fnp-2845	104	42	hpcs	hpc	NOUN
fnp-2845	104	43	(	(	PUNCT
fnp-2845	104	44	totalp	totalp	NOUN
fnp-2845	104	45	=	=	SYM
fnp-2845	104	46	0.1	0.1	NUM
fnp-2845	104	47	;	;	PUNCT
fnp-2845	104	48	fibrillarp	fibrillarp	NOUN
fnp-2845	104	49	=	=	SYM
fnp-2845	104	50	0.06	0.06	NUM
fnp-2845	104	51	;	;	PUNCT
fnp-2845	104	52	dense	dense	ADJ
fnp-2845	104	53	-	-	PUNCT
fnp-2845	104	54	coredp	coredp	ADJ
fnp-2845	104	55	=	=	ADJ
fnp-2845	104	56	0.2	0.2	NUM
fnp-2845	104	57	)	)	PUNCT
fnp-2845	104	58	.	.	PUNCT
fnp-2845	105	1	total	total	ADJ
fnp-2845	105	2	tau	tau	PROPN
fnp-2845	105	3	areal	areal	PROPN
fnp-2845	105	4	fraction	fraction	NOUN
fnp-2845	105	5	(	(	PUNCT
fnp-2845	105	6	%	%	INTJ
fnp-2845	105	7	ttau	ttau	ADJ
fnp-2845	105	8	)	)	PUNCT
fnp-2845	105	9	and	and	CCONJ
fnp-2845	105	10	the	the	DET
fnp-2845	105	11	density	density	NOUN
fnp-2845	105	12	of	of	ADP
fnp-2845	105	13	nfts	nft	NOUN
fnp-2845	105	14	was	be	AUX
fnp-2845	105	15	higher	high	ADJ
fnp-2845	105	16	in	in	ADP
fnp-2845	105	17	the	the	DET
fnp-2845	105	18	pmc	pmc	NOUN
fnp-2845	105	19	of	of	ADP
fnp-2845	105	20	ad	ad	NOUN
fnp-2845	105	21	cases	case	NOUN
fnp-2845	105	22	compared	compare	VERB
fnp-2845	105	23	to	to	ADP
fnp-2845	105	24	controls	control	NOUN
fnp-2845	105	25	(	(	PUNCT
fnp-2845	105	26	%	%	INTJ
fnp-2845	105	27	ttaup	ttaup	NOUN
fnp-2845	105	28	=	=	NOUN
fnp-2845	105	29	0.001	0.001	NUM
fnp-2845	105	30	;	;	PUNCT
fnp-2845	105	31	nftp	nftp	NOUN
fnp-2845	105	32	=	=	NOUN
fnp-2845	105	33	0.001	0.001	NUM
fnp-2845	105	34	)	)	PUNCT
fnp-2845	105	35	and	and	CCONJ
fnp-2845	105	36	hpcs	hpc	NOUN
fnp-2845	105	37	(	(	PUNCT
fnp-2845	105	38	%	%	INTJ
fnp-2845	105	39	ttaup	ttaup	NOUN
fnp-2845	105	40	=	=	NOUN
fnp-2845	105	41	0.007	0.007	NUM
fnp-2845	105	42	;	;	PUNCT
fnp-2845	105	43	nftp	nftp	NOUN
fnp-2845	105	44	=	=	NOUN
fnp-2845	105	45	0.01	0.01	NUM
fnp-2845	105	46	)	)	PUNCT
fnp-2845	105	47	(	(	PUNCT
fnp-2845	105	48	table	table	NOUN
fnp-2845	105	49	2	2	NUM
fnp-2845	105	50	)	)	PUNCT
fnp-2845	105	51	.	.	PUNCT
fnp-2845	106	1	amongst	amongst	ADP
fnp-2845	106	2	the	the	DET
fnp-2845	106	3	ad	ad	NOUN
fnp-2845	106	4	cases	case	NOUN
fnp-2845	106	5	,	,	PUNCT
fnp-2845	106	6	the	the	DET
fnp-2845	106	7	pmc	pmc	PROPN
fnp-2845	106	8	had	have	AUX
fnp-2845	106	9	significantly	significantly	ADV
fnp-2845	106	10	reduced	reduce	VERB
fnp-2845	106	11	%	%	INTJ
fnp-2845	107	1	aβ	aβ	INTJ
fnp-2845	107	2	(	(	PUNCT
fnp-2845	107	3	p	p	NOUN
fnp-2845	107	4	=	=	NOUN
fnp-2845	107	5	0.006	0.006	NUM
fnp-2845	107	6	)	)	PUNCT
fnp-2845	107	7	,	,	PUNCT
fnp-2845	107	8	total	total	NOUN
fnp-2845	107	9	aβ	aβ	PRON
fnp-2845	107	10	plaques	plaque	NOUN
fnp-2845	107	11	(	(	PUNCT
fnp-2845	107	12	0.001	0.001	NUM
fnp-2845	107	13	)	)	PUNCT
fnp-2845	107	14	,	,	PUNCT
fnp-2845	107	15	and	and	CCONJ
fnp-2845	107	16	fibrillar	fibrillar	ADJ
fnp-2845	107	17	plaques	plaque	NOUN
fnp-2845	107	18	(	(	PUNCT
fnp-2845	107	19	p	p	X
fnp-2845	107	20	=	=	NOUN
fnp-2845	107	21	0.0002	0.0002	NUM
fnp-2845	107	22	)	)	PUNCT
fnp-2845	107	23	,	,	PUNCT
fnp-2845	107	24	but	but	CCONJ
fnp-2845	107	25	not	not	PART
fnp-2845	107	26	dense	dense	ADV
fnp-2845	107	27	-	-	PUNCT
fnp-2845	107	28	cored	core	VERB
fnp-2845	107	29	plaques	plaque	NOUN
fnp-2845	107	30	(	(	PUNCT
fnp-2845	107	31	p	p	NOUN
fnp-2845	107	32	=	=	NOUN
fnp-2845	107	33	0.2	0.2	NUM
fnp-2845	107	34	)	)	PUNCT
fnp-2845	107	35	compared	compare	VERB
fnp-2845	107	36	to	to	ADP
fnp-2845	107	37	the	the	DET
fnp-2845	107	38	itc	itc	PROPN
fnp-2845	107	39	.	.	PUNCT
fnp-2845	108	1	the	the	DET
fnp-2845	108	2	%	%	NOUN
fnp-2845	108	3	ttau	ttau	ADV
fnp-2845	108	4	(	(	PUNCT
fnp-2845	108	5	p	p	X
fnp-2845	108	6	=	=	NOUN
fnp-2845	108	7	0.02	0.02	NUM
fnp-2845	108	8	)	)	PUNCT
fnp-2845	108	9	and	and	CCONJ
fnp-2845	108	10	the	the	DET
fnp-2845	108	11	density	density	NOUN
fnp-2845	108	12	of	of	ADP
fnp-2845	108	13	nfts	nft	NOUN
fnp-2845	108	14	(	(	PUNCT
fnp-2845	108	15	p	p	NOUN
fnp-2845	108	16	=	=	NOUN
fnp-2845	108	17	0.02	0.02	NUM
fnp-2845	108	18	)	)	PUNCT
fnp-2845	108	19	were	be	AUX
fnp-2845	108	20	also	also	ADV
fnp-2845	108	21	significantly	significantly	ADV
fnp-2845	108	22	reduced	reduce	VERB
fnp-2845	108	23	in	in	ADP
fnp-2845	108	24	the	the	DET
fnp-2845	108	25	pmc	pmc	NOUN
fnp-2845	108	26	compared	compare	VERB
fnp-2845	108	27	to	to	ADP
fnp-2845	108	28	the	the	DET
fnp-2845	108	29	itc	itc	NOUN
fnp-2845	108	30	of	of	ADP
fnp-2845	108	31	ad	ad	NOUN
fnp-2845	108	32	cases	case	NOUN
fnp-2845	108	33	.	.	PUNCT
fnp-2845	109	1	amongst	amongst	ADP
fnp-2845	109	2	controls	control	VERB
fnp-2845	109	3	the	the	DET
fnp-2845	109	4	%	%	NOUN
fnp-2845	109	5	ttau	ttau	PRON
fnp-2845	109	6	was	be	AUX
fnp-2845	109	7	significantly	significantly	ADV
fnp-2845	109	8	reduced	reduce	VERB
fnp-2845	109	9	in	in	ADP
fnp-2845	109	10	the	the	DET
fnp-2845	109	11	pmc	pmc	NOUN
fnp-2845	109	12	compared	compare	VERB
fnp-2845	109	13	to	to	ADP
fnp-2845	109	14	the	the	DET
fnp-2845	109	15	itc	itc	PROPN
fnp-2845	109	16	(	(	PUNCT
fnp-2845	109	17	p	p	X
fnp-2845	109	18	=	=	NOUN
fnp-2845	109	19	0.04	0.04	NUM
fnp-2845	109	20	)	)	PUNCT
fnp-2845	109	21	.	.	PUNCT
fnp-2845	110	1	there	there	PRON
fnp-2845	110	2	were	be	VERB
fnp-2845	110	3	no	no	DET
fnp-2845	110	4	other	other	ADJ
fnp-2845	110	5	regional	regional	ADJ
fnp-2845	110	6	differences	difference	NOUN
fnp-2845	110	7	in	in	ADP
fnp-2845	110	8	terms	term	NOUN
fnp-2845	110	9	of	of	ADP
fnp-2845	110	10	pathological	pathological	ADJ
fnp-2845	110	11	load	load	NOUN
fnp-2845	110	12	in	in	ADP
fnp-2845	110	13	controls	control	NOUN
fnp-2845	110	14	,	,	PUNCT
fnp-2845	110	15	including	include	VERB
fnp-2845	110	16	amongst	amongst	ADP
fnp-2845	110	17	hpcs	hpc	NOUN
fnp-2845	110	18	(	(	PUNCT
fnp-2845	110	19	table	table	NOUN
fnp-2845	110	20	3	3	NUM
fnp-2845	110	21	)	)	PUNCT
fnp-2845	110	22	.	.	PUNCT
fnp-2845	111	1	in	in	ADP
fnp-2845	111	2	the	the	DET
fnp-2845	111	3	itc	itc	PROPN
fnp-2845	111	4	,	,	PUNCT
fnp-2845	111	5	all	all	PRON
fnp-2845	111	6	of	of	ADP
fnp-2845	111	7	the	the	DET
fnp-2845	111	8	control	control	NOUN
fnp-2845	111	9	,	,	PUNCT
fnp-2845	111	10	hpc	hpc	PROPN
fnp-2845	111	11	,	,	PUNCT
fnp-2845	111	12	and	and	CCONJ
fnp-2845	111	13	ad	ad	NOUN
fnp-2845	111	14	cases	case	NOUN
fnp-2845	111	15	had	have	VERB
fnp-2845	111	16	neuritic	neuritic	ADJ
fnp-2845	111	17	tau	tau	NOUN
fnp-2845	111	18	pathology	pathology	NOUN
fnp-2845	111	19	at	at	ADP
fnp-2845	111	20	varied	varied	ADJ
fnp-2845	111	21	levels	level	NOUN
fnp-2845	111	22	.	.	PUNCT
fnp-2845	112	1	aβ	aβ	DET
fnp-2845	112	2	pathology	pathology	NOUN
fnp-2845	112	3	in	in	ADP
fnp-2845	112	4	the	the	DET
fnp-2845	112	5	itc	itc	PROPN
fnp-2845	112	6	occurred	occur	VERB
fnp-2845	112	7	in	in	ADP
fnp-2845	112	8	4/10	4/10	NUM
fnp-2845	112	9	controls	control	NOUN
fnp-2845	112	10	,	,	PUNCT
fnp-2845	112	11	and	and	CCONJ
fnp-2845	112	12	all	all	DET
fnp-2845	112	13	hpcs	hpc	NOUN
fnp-2845	112	14	and	and	CCONJ
fnp-2845	112	15	ad	ad	NOUN
fnp-2845	112	16	cases	case	NOUN
fnp-2845	112	17	.	.	PUNCT
fnp-2845	113	1	the	the	DET
fnp-2845	113	2	clustering	clustering	NOUN
fnp-2845	113	3	of	of	ADP
fnp-2845	113	4	activated	activated	ADJ
fnp-2845	113	5	microglia	microglia	NOUN
fnp-2845	113	6	in	in	ADP
fnp-2845	113	7	the	the	DET
fnp-2845	113	8	itc	itc	NOUN
fnp-2845	113	9	was	be	AUX
fnp-2845	113	10	apparent	apparent	ADJ
fnp-2845	113	11	in	in	ADP
fnp-2845	113	12	6/10	6/10	NUM
fnp-2845	113	13	controls	control	NOUN
fnp-2845	113	14	(	(	PUNCT
fnp-2845	113	15	including	include	VERB
fnp-2845	113	16	three	three	NUM
fnp-2845	113	17	with	with	ADP
fnp-2845	113	18	only	only	ADJ
fnp-2845	113	19	tau	tau	PROPN
fnp-2845	113	20	pathology	pathology	NOUN
fnp-2845	113	21	)	)	PUNCT
fnp-2845	113	22	,	,	PUNCT
fnp-2845	113	23	and	and	CCONJ
fnp-2845	113	24	all	all	PRON
fnp-2845	113	25	of	of	ADP
fnp-2845	113	26	the	the	DET
fnp-2845	113	27	hpcs	hpc	NOUN
fnp-2845	113	28	and	and	CCONJ
fnp-2845	113	29	ad	ad	NOUN
fnp-2845	113	30	cases	case	NOUN
fnp-2845	113	31	except	except	SCONJ
fnp-2845	113	32	one	one	NUM
fnp-2845	113	33	(	(	PUNCT
fnp-2845	113	34	m12	m12	PROPN
fnp-2845	113	35	)	)	PUNCT
fnp-2845	113	36	(	(	PUNCT
fnp-2845	113	37	itc	itc	PROPN
fnp-2845	113	38	case	case	NOUN
fnp-2845	113	39	data	datum	NOUN
fnp-2845	113	40	is	be	AUX
fnp-2845	113	41	shown	show	VERB
fnp-2845	113	42	in	in	ADP
fnp-2845	113	43	fig	fig	NOUN
fnp-2845	113	44	.	.	PUNCT
fnp-2845	114	1	1d	1d	NUM
fnp-2845	114	2	)	)	PUNCT
fnp-2845	114	3	.	.	PUNCT
fnp-2845	115	1	in	in	ADP
fnp-2845	115	2	the	the	DET
fnp-2845	115	3	pmc	pmc	PROPN
fnp-2845	115	4	,	,	PUNCT
fnp-2845	115	5	neuritic	neuritic	PROPN
fnp-2845	115	6	tau	tau	PROPN
fnp-2845	115	7	pathology	pathology	NOUN
fnp-2845	115	8	was	be	AUX
fnp-2845	115	9	present	present	ADJ
fnp-2845	115	10	in	in	ADP
fnp-2845	115	11	7/10	7/10	NUM
fnp-2845	115	12	controls	control	NOUN
fnp-2845	115	13	,	,	PUNCT
fnp-2845	115	14	4/5	4/5	NUM
fnp-2845	115	15	hpcs	hpc	NOUN
fnp-2845	115	16	,	,	PUNCT
fnp-2845	115	17	and	and	CCONJ
fnp-2845	115	18	all	all	DET
fnp-2845	115	19	ad	ad	NOUN
fnp-2845	115	20	cases	case	NOUN
fnp-2845	115	21	,	,	PUNCT
fnp-2845	115	22	while	while	SCONJ
fnp-2845	115	23	aβ	aβ	PRON
fnp-2845	115	24	deposition	deposition	NOUN
fnp-2845	115	25	in	in	ADP
fnp-2845	115	26	the	the	DET
fnp-2845	115	27	pmc	pmc	PROPN
fnp-2845	115	28	occurred	occur	VERB
fnp-2845	115	29	in	in	ADP
fnp-2845	115	30	6/10	6/10	NUM
fnp-2845	115	31	controls	control	NOUN
fnp-2845	115	32	,	,	PUNCT
fnp-2845	115	33	4/5	4/5	NUM
fnp-2845	115	34	hpcs	hpc	NOUN
fnp-2845	115	35	,	,	PUNCT
fnp-2845	115	36	and	and	CCONJ
fnp-2845	115	37	all	all	DET
fnp-2845	115	38	ad	ad	NOUN
fnp-2845	115	39	cases	case	NOUN
fnp-2845	115	40	.	.	PUNCT
fnp-2845	116	1	microglial	microglial	ADJ
fnp-2845	116	2	clustering	clustering	NOUN
fnp-2845	116	3	in	in	ADP
fnp-2845	116	4	the	the	DET
fnp-2845	116	5	pmc	pmc	PROPN
fnp-2845	116	6	was	be	AUX
fnp-2845	116	7	observed	observe	VERB
fnp-2845	116	8	in	in	ADP
fnp-2845	116	9	5/10	5/10	NUM
fnp-2845	116	10	controls	control	NOUN
fnp-2845	116	11	,	,	PUNCT
fnp-2845	116	12	and	and	CCONJ
fnp-2845	116	13	all	all	PRON
fnp-2845	116	14	of	of	ADP
fnp-2845	116	15	the	the	DET
fnp-2845	116	16	hpcs	hpc	NOUN
fnp-2845	116	17	and	and	CCONJ
fnp-2845	116	18	ad	ad	NOUN
fnp-2845	116	19	cases	case	NOUN
fnp-2845	116	20	,	,	PUNCT
fnp-2845	116	21	with	with	ADP
fnp-2845	116	22	the	the	DET
fnp-2845	116	23	exception	exception	NOUN
fnp-2845	116	24	of	of	ADP
fnp-2845	116	25	one	one	NUM
fnp-2845	116	26	case	case	NOUN
fnp-2845	116	27	(	(	PUNCT
fnp-2845	116	28	m12	m12	PROPN
fnp-2845	116	29	)	)	PUNCT
fnp-2845	116	30	(	(	PUNCT
fnp-2845	116	31	pmc	pmc	NOUN
fnp-2845	116	32	case	case	NOUN
fnp-2845	116	33	data	datum	NOUN
fnp-2845	116	34	is	be	AUX
fnp-2845	116	35	shown	show	VERB
fnp-2845	116	36	in	in	ADP
fnp-2845	116	37	fig	fig	NOUN
fnp-2845	116	38	.	.	PUNCT
fnp-2845	117	1	1e	1e	NUM
fnp-2845	117	2	)	)	PUNCT
fnp-2845	117	3	.	.	PUNCT
fnp-2845	118	1	in	in	ADP
fnp-2845	118	2	controls	control	NOUN
fnp-2845	118	3	,	,	PUNCT
fnp-2845	118	4	the	the	DET
fnp-2845	118	5	%	%	NOUN
fnp-2845	118	6	ttau	ttau	ADV
fnp-2845	118	7	correlated	correlate	VERB
fnp-2845	118	8	with	with	ADP
fnp-2845	118	9	age	age	NOUN
fnp-2845	118	10	in	in	ADP
fnp-2845	118	11	the	the	DET
fnp-2845	118	12	pmc	pmc	PROPN
fnp-2845	118	13	(	(	PUNCT
fnp-2845	118	14	r2	r2	PROPN
fnp-2845	118	15	=	=	SYM
fnp-2845	118	16	0.44	0.44	NUM
fnp-2845	118	17	,	,	PUNCT
fnp-2845	118	18	p	p	X
fnp-2845	118	19	=	=	NOUN
fnp-2845	118	20	0.04	0.04	NUM
fnp-2845	118	21	)	)	PUNCT
fnp-2845	118	22	but	but	CCONJ
fnp-2845	118	23	not	not	PART
fnp-2845	118	24	in	in	ADP
fnp-2845	118	25	the	the	DET
fnp-2845	118	26	itc	itc	PROPN
fnp-2845	118	27	,	,	PUNCT
fnp-2845	118	28	which	which	PRON
fnp-2845	118	29	was	be	AUX
fnp-2845	118	30	near	near	ADP
fnp-2845	118	31	significant	significant	ADJ
fnp-2845	118	32	(	(	PUNCT
fnp-2845	118	33	r2	r2	NOUN
fnp-2845	118	34	=	=	SYM
fnp-2845	118	35	0.39	0.39	NUM
fnp-2845	118	36	,	,	PUNCT
fnp-2845	118	37	p	p	X
fnp-2845	118	38	=	=	NOUN
fnp-2845	118	39	0.05	0.05	NUM
fnp-2845	118	40	)	)	PUNCT
fnp-2845	118	41	.	.	PUNCT
fnp-2845	119	1	figure	figure	VERB
fnp-2845	119	2	1	1	NUM
fnp-2845	119	3	characteristics	characteristic	NOUN
fnp-2845	119	4	of	of	ADP
fnp-2845	119	5	the	the	DET
fnp-2845	119	6	pmc	pmc	PROPN
fnp-2845	119	7	and	and	CCONJ
fnp-2845	119	8	regional	regional	ADJ
fnp-2845	119	9	neuropathological	neuropathological	ADJ
fnp-2845	119	10	comparisons	comparison	NOUN
fnp-2845	119	11	.	.	PUNCT
fnp-2845	120	1	a	a	X
fnp-2845	120	2	–	–	PUNCT
fnp-2845	120	3	c	c	NOUN
fnp-2845	120	4	the	the	DET
fnp-2845	120	5	pmc	pmc	PROPN
fnp-2845	120	6	is	be	AUX
fnp-2845	120	7	spared	spare	VERB
fnp-2845	120	8	of	of	ADP
fnp-2845	120	9	ad	ad	NOUN
fnp-2845	120	10	-	-	PUNCT
fnp-2845	120	11	related	relate	VERB
fnp-2845	120	12	neurodegenerative	neurodegenerative	ADJ
fnp-2845	120	13	changes	change	NOUN
fnp-2845	120	14	as	as	SCONJ
fnp-2845	120	15	measured	measure	VERB
fnp-2845	120	16	by	by	ADP
fnp-2845	120	17	cortical	cortical	ADJ
fnp-2845	120	18	thickness	thickness	NOUN
fnp-2845	120	19	(	(	PUNCT
fnp-2845	120	20	a	a	NOUN
fnp-2845	120	21	)	)	PUNCT
fnp-2845	120	22	,	,	PUNCT
fnp-2845	120	23	total	total	ADJ
fnp-2845	120	24	neuronal	neuronal	ADJ
fnp-2845	120	25	density	density	NOUN
fnp-2845	120	26	(	(	PUNCT
fnp-2845	120	27	b	b	NOUN
fnp-2845	120	28	)	)	PUNCT
fnp-2845	120	29	,	,	PUNCT
fnp-2845	120	30	and	and	CCONJ
fnp-2845	120	31	the	the	DET
fnp-2845	120	32	density	density	NOUN
fnp-2845	120	33	of	of	ADP
fnp-2845	120	34	layer	layer	NOUN
fnp-2845	120	35	vb	vb	PROPN
fnp-2845	120	36	betz	betz	PROPN
fnp-2845	120	37	cells	cell	NOUN
fnp-2845	120	38	(	(	PUNCT
fnp-2845	120	39	inset	inset	NOUN
fnp-2845	120	40	demonstrates	demonstrate	VERB
fnp-2845	120	41	a	a	DET
fnp-2845	120	42	pyramidal	pyramidal	ADJ
fnp-2845	120	43	betz	betz	NOUN
fnp-2845	120	44	cell	cell	NOUN
fnp-2845	120	45	with	with	ADP
fnp-2845	120	46	multiple	multiple	ADJ
fnp-2845	120	47	asymmetrically	asymmetrically	ADV
fnp-2845	120	48	distributed	distribute	VERB
fnp-2845	120	49	perisomatic	perisomatic	ADJ
fnp-2845	120	50	neurites	neurite	NOUN
fnp-2845	120	51	,	,	PUNCT
fnp-2845	120	52	a	a	DET
fnp-2845	120	53	prominent	prominent	ADJ
fnp-2845	120	54	nucleolus	nucleolus	NOUN
fnp-2845	120	55	,	,	PUNCT
fnp-2845	120	56	and	and	CCONJ
fnp-2845	120	57	a	a	DET
fnp-2845	120	58	dark	dark	ADJ
fnp-2845	120	59	dense	dense	ADJ
fnp-2845	120	60	deposit	deposit	NOUN
fnp-2845	120	61	of	of	ADP
fnp-2845	120	62	cytoplasmic	cytoplasmic	ADJ
fnp-2845	120	63	lipofuscin	lipofuscin	PROPN
fnp-2845	120	64	)	)	PUNCT
fnp-2845	120	65	(	(	PUNCT
fnp-2845	120	66	c	c	NOUN
fnp-2845	120	67	)	)	PUNCT
fnp-2845	120	68	.	.	PUNCT
fnp-2845	121	1	d	d	X
fnp-2845	121	2	–	–	PUNCT
fnp-2845	121	3	e	e	X
fnp-2845	121	4	a	a	DET
fnp-2845	121	5	cohort	cohort	NOUN
fnp-2845	121	6	wide	wide	ADJ
fnp-2845	121	7	comparison	comparison	NOUN
fnp-2845	121	8	of	of	ADP
fnp-2845	121	9	the	the	DET
fnp-2845	121	10	percentage	percentage	NOUN
fnp-2845	121	11	of	of	ADP
fnp-2845	121	12	aβ	aβ	NOUN
fnp-2845	121	13	and	and	CCONJ
fnp-2845	121	14	ttau	ttau	AUX
fnp-2845	121	15	immunolabelling	immunolabelle	VERB
fnp-2845	121	16	and	and	CCONJ
fnp-2845	121	17	microglial	microglial	ADJ
fnp-2845	121	18	clustering	clustering	NOUN
fnp-2845	121	19	in	in	ADP
fnp-2845	121	20	the	the	DET
fnp-2845	121	21	itc	itc	PROPN
fnp-2845	121	22	(	(	PUNCT
fnp-2845	121	23	d	d	NOUN
fnp-2845	121	24	)	)	PUNCT
fnp-2845	121	25	and	and	CCONJ
fnp-2845	121	26	pmc	pmc	PROPN
fnp-2845	121	27	(	(	PUNCT
fnp-2845	121	28	e	e	NOUN
fnp-2845	121	29	)	)	PUNCT
fnp-2845	121	30	demonstrates	demonstrate	VERB
fnp-2845	121	31	age	age	NOUN
fnp-2845	121	32	-	-	PUNCT
fnp-2845	121	33	related	relate	VERB
fnp-2845	121	34	tau	tau	NOUN
fnp-2845	121	35	build	build	NOUN
fnp-2845	121	36	-	-	PUNCT
fnp-2845	121	37	up	up	NOUN
fnp-2845	121	38	in	in	ADP
fnp-2845	121	39	a	a	DET
fnp-2845	121	40	majority	majority	NOUN
fnp-2845	121	41	of	of	ADP
fnp-2845	121	42	control	control	NOUN
fnp-2845	121	43	brains	brain	NOUN
fnp-2845	121	44	in	in	ADP
fnp-2845	121	45	both	both	DET
fnp-2845	121	46	regions	region	NOUN
fnp-2845	121	47	and	and	CCONJ
fnp-2845	121	48	an	an	DET
fnp-2845	121	49	early	early	ADJ
fnp-2845	121	50	build	build	NOUN
fnp-2845	121	51	-	-	PUNCT
fnp-2845	121	52	up	up	NOUN
fnp-2845	121	53	of	of	ADP
fnp-2845	121	54	aβ	aβ	PRON
fnp-2845	121	55	in	in	ADP
fnp-2845	121	56	hpcs	hpc	NOUN
fnp-2845	121	57	(	(	PUNCT
fnp-2845	121	58	that	that	PRON
fnp-2845	121	59	were	be	AUX
fnp-2845	121	60	scored	score	VERB
fnp-2845	121	61	as	as	ADP
fnp-2845	121	62	a2	a2	NOUN
fnp-2845	121	63	-	-	PUNCT
fnp-2845	121	64	3	3	NUM
fnp-2845	121	65	,	,	PUNCT
fnp-2845	121	66	b2	b2	NOUN
fnp-2845	121	67	,	,	PUNCT
fnp-2845	121	68	c0	c0	NOUN
fnp-2845	121	69	-	-	PUNCT
fnp-2845	121	70	3	3	NUM
fnp-2845	121	71	on	on	ADP
fnp-2845	121	72	diagnostic	diagnostic	ADJ
fnp-2845	121	73	slides	slide	NOUN
fnp-2845	121	74	)	)	PUNCT
fnp-2845	121	75	with	with	ADP
fnp-2845	121	76	a	a	DET
fnp-2845	121	77	concomitant	concomitant	ADJ
fnp-2845	121	78	microglial	microglial	ADJ
fnp-2845	121	79	clustering	clustering	ADJ
fnp-2845	121	80	response	response	NOUN
fnp-2845	121	81	that	that	PRON
fnp-2845	121	82	is	be	AUX
fnp-2845	121	83	more	more	ADV
fnp-2845	121	84	prevalent	prevalent	ADJ
fnp-2845	121	85	in	in	ADP
fnp-2845	121	86	the	the	DET
fnp-2845	121	87	pmc	pmc	NOUN
fnp-2845	121	88	compared	compare	VERB
fnp-2845	121	89	to	to	ADP
fnp-2845	121	90	the	the	DET
fnp-2845	121	91	itc	itc	PROPN
fnp-2845	121	92	and	and	CCONJ
fnp-2845	121	93	which	which	PRON
fnp-2845	121	94	appears	appear	VERB
fnp-2845	121	95	to	to	PART
fnp-2845	121	96	dissipate	dissipate	VERB
fnp-2845	121	97	with	with	ADP
fnp-2845	121	98	severe	severe	ADJ
fnp-2845	121	99	ad	ad	NOUN
fnp-2845	121	100	pathology	pathology	NOUN
fnp-2845	121	101	in	in	ADP
fnp-2845	121	102	the	the	DET
fnp-2845	121	103	itc	itc	PROPN
fnp-2845	121	104	.	.	PUNCT
fnp-2845	121	105	scale	scale	NOUN
fnp-2845	121	106	bar	bar	NOUN
fnp-2845	121	107	=	=	PUNCT
fnp-2845	121	108	50	50	NUM
fnp-2845	121	109	μm	μm	NOUN
fnp-2845	121	110	(	(	PUNCT
fnp-2845	121	111	c	c	NOUN
fnp-2845	121	112	)	)	PUNCT
fnp-2845	121	113	table	table	NOUN
fnp-2845	121	114	2	2	NUM
fnp-2845	121	115	.	.	X
fnp-2845	122	1	summary	summary	NOUN
fnp-2845	122	2	of	of	ADP
fnp-2845	122	3	neuronal	neuronal	ADJ
fnp-2845	122	4	and	and	CCONJ
fnp-2845	122	5	neuropathological	neuropathological	ADJ
fnp-2845	122	6	data	datum	NOUN
fnp-2845	122	7	of	of	ADP
fnp-2845	122	8	the	the	DET
fnp-2845	122	9	primary	primary	ADJ
fnp-2845	122	10	motor	motor	PROPN
fnp-2845	122	11	cortexa	cortexa	PROPN
fnp-2845	122	12	amean	amean	PROPN
fnp-2845	122	13	±	±	PROPN
fnp-2845	122	14	standard	standard	ADJ
fnp-2845	122	15	deviation	deviation	NOUN
fnp-2845	122	16	.	.	PUNCT
fnp-2845	123	1	banova	banova	PROPN
fnp-2845	123	2	results	result	NOUN
fnp-2845	123	3	;	;	PUNCT
fnp-2845	123	4	see	see	VERB
fnp-2845	123	5	text	text	NOUN
fnp-2845	123	6	for	for	ADP
fnp-2845	123	7	p	p	NOUN
fnp-2845	123	8	-	-	PUNCT
fnp-2845	123	9	values	value	NOUN
fnp-2845	123	10	of	of	ADP
fnp-2845	123	11	pairwise	pairwise	NOUN
fnp-2845	123	12	comparisons	comparison	NOUN
fnp-2845	123	13	.	.	PUNCT
fnp-2845	124	1	cinclusive	cinclusive	PROPN
fnp-2845	124	2	of	of	ADP
fnp-2845	124	3	betz	betz	PROPN
fnp-2845	124	4	cells	cell	NOUN
fnp-2845	124	5	.	.	PUNCT
fnp-2845	125	1	ddensity	ddensity	NOUN
fnp-2845	125	2	of	of	ADP
fnp-2845	125	3	betz	betz	PROPN
fnp-2845	125	4	cells	cell	NOUN
fnp-2845	125	5	in	in	ADP
fnp-2845	125	6	layer	layer	NOUN
fnp-2845	125	7	v.	v.	ADP
fnp-2845	125	8	table	table	NOUN
fnp-2845	125	9	3	3	NUM
fnp-2845	125	10	.	.	X
fnp-2845	126	1	regional	regional	ADJ
fnp-2845	126	2	neuropathological	neuropathological	ADJ
fnp-2845	126	3	comparisonsa	comparisonsa	NOUN
fnp-2845	126	4	amean	amean	PROPN
fnp-2845	126	5	±	±	PROPN
fnp-2845	126	6	standard	standard	ADJ
fnp-2845	126	7	deviation	deviation	NOUN
fnp-2845	126	8	.	.	PUNCT
fnp-2845	127	1	clusters	cluster	NOUN
fnp-2845	127	2	of	of	ADP
fnp-2845	127	3	activated	activate	VERB
fnp-2845	127	4	microglia	microglia	NOUN
fnp-2845	127	5	are	be	AUX
fnp-2845	127	6	more	more	ADV
fnp-2845	127	7	commonly	commonly	ADV
fnp-2845	127	8	found	find	VERB
fnp-2845	127	9	in	in	ADP
fnp-2845	127	10	the	the	DET
fnp-2845	127	11	pmc	pmc	PROPN
fnp-2845	127	12	than	than	ADP
fnp-2845	127	13	the	the	DET
fnp-2845	127	14	itc	itc	PROPN
fnp-2845	127	15	of	of	ADP
fnp-2845	127	16	hpcs	hpc	NOUN
fnp-2845	127	17	and	and	CCONJ
fnp-2845	127	18	ad	ad	NOUN
fnp-2845	127	19	cases	case	NOUN
fnp-2845	127	20	the	the	DET
fnp-2845	127	21	density	density	NOUN
fnp-2845	127	22	of	of	ADP
fnp-2845	127	23	individual	individual	ADJ
fnp-2845	127	24	activated	activate	VERB
fnp-2845	127	25	(	(	PUNCT
fnp-2845	127	26	fig	fig	NOUN
fnp-2845	127	27	.	.	PUNCT
fnp-2845	128	1	2a	2a	NUM
fnp-2845	128	2	–	–	PUNCT
fnp-2845	128	3	e	e	NOUN
fnp-2845	128	4	)	)	PUNCT
fnp-2845	128	5	,	,	PUNCT
fnp-2845	128	6	ramified	ramify	VERB
fnp-2845	128	7	(	(	PUNCT
fnp-2845	128	8	fig	fig	NOUN
fnp-2845	128	9	.	.	PUNCT
fnp-2845	129	1	2f	2f	NUM
fnp-2845	129	2	)	)	PUNCT
fnp-2845	130	1	,	,	PUNCT
fnp-2845	130	2	dystrophic	dystrophic	ADJ
fnp-2845	130	3	(	(	PUNCT
fnp-2845	130	4	fig	fig	NOUN
fnp-2845	130	5	.	.	PUNCT
fnp-2845	131	1	2g	2g	NOUN
fnp-2845	131	2	–	–	PUNCT
fnp-2845	131	3	h	h	NOUN
fnp-2845	131	4	)	)	PUNCT
fnp-2845	131	5	,	,	PUNCT
fnp-2845	131	6	or	or	CCONJ
fnp-2845	131	7	total	total	ADJ
fnp-2845	131	8	microglia	microglia	NOUN
fnp-2845	131	9	did	do	AUX
fnp-2845	131	10	not	not	PART
fnp-2845	131	11	differ	differ	VERB
fnp-2845	131	12	between	between	ADP
fnp-2845	131	13	any	any	PRON
fnp-2845	131	14	of	of	ADP
fnp-2845	131	15	the	the	DET
fnp-2845	131	16	three	three	NUM
fnp-2845	131	17	groups	group	NOUN
fnp-2845	131	18	in	in	ADP
fnp-2845	131	19	the	the	DET
fnp-2845	131	20	pmc	pmc	PROPN
fnp-2845	131	21	(	(	PUNCT
fnp-2845	131	22	table	table	NOUN
fnp-2845	131	23	4	4	NUM
fnp-2845	131	24	)	)	PUNCT
fnp-2845	131	25	.	.	PUNCT
fnp-2845	132	1	microglial	microglial	ADJ
fnp-2845	132	2	clusters	cluster	NOUN
fnp-2845	132	3	(	(	PUNCT
fnp-2845	132	4	fig	fig	NOUN
fnp-2845	132	5	.	.	PUNCT
fnp-2845	132	6	2i	2i	NUM
fnp-2845	132	7	–	–	PUNCT
fnp-2845	132	8	j	j	NOUN
fnp-2845	132	9	)	)	PUNCT
fnp-2845	132	10	,	,	PUNCT
fnp-2845	132	11	although	although	SCONJ
fnp-2845	132	12	a	a	DET
fnp-2845	132	13	small	small	ADJ
fnp-2845	132	14	proportion	proportion	NOUN
fnp-2845	132	15	of	of	ADP
fnp-2845	132	16	total	total	ADJ
fnp-2845	132	17	microglia	microglia	NOUN
fnp-2845	132	18	,	,	PUNCT
fnp-2845	132	19	were	be	AUX
fnp-2845	132	20	significantly	significantly	ADV
fnp-2845	132	21	more	more	ADV
fnp-2845	132	22	common	common	ADJ
fnp-2845	132	23	in	in	ADP
fnp-2845	132	24	hpcs	hpc	NOUN
fnp-2845	132	25	(	(	PUNCT
fnp-2845	132	26	fig	fig	NOUN
fnp-2845	132	27	.	.	PUNCT
fnp-2845	132	28	2k	2k	NUM
fnp-2845	132	29	)	)	PUNCT
fnp-2845	132	30	and	and	CCONJ
fnp-2845	132	31	ad	ad	NOUN
fnp-2845	132	32	(	(	PUNCT
fnp-2845	132	33	fig	fig	NOUN
fnp-2845	132	34	.	.	PUNCT
fnp-2845	133	1	2l	2l	NUM
fnp-2845	133	2	)	)	PUNCT
fnp-2845	133	3	cases	case	NOUN
fnp-2845	133	4	compared	compare	VERB
fnp-2845	133	5	to	to	ADP
fnp-2845	133	6	controls	control	NOUN
fnp-2845	133	7	in	in	ADP
fnp-2845	133	8	the	the	DET
fnp-2845	133	9	pmc	pmc	PROPN
fnp-2845	133	10	(	(	PUNCT
fnp-2845	133	11	hpc	hpc	PROPN
fnp-2845	133	12	p	p	NOUN
fnp-2845	133	13	=	=	PROPN
fnp-2845	133	14	0.01	0.01	NUM
fnp-2845	133	15	;	;	PUNCT
fnp-2845	133	16	ad	ad	NOUN
fnp-2845	133	17	p	p	NOUN
fnp-2845	133	18	=	=	NOUN
fnp-2845	133	19	0.04	0.04	NUM
fnp-2845	133	20	)	)	PUNCT
fnp-2845	133	21	.	.	PUNCT
fnp-2845	134	1	clusters	cluster	NOUN
fnp-2845	134	2	in	in	ADP
fnp-2845	134	3	the	the	DET
fnp-2845	134	4	pmc	pmc	PROPN
fnp-2845	134	5	were	be	AUX
fnp-2845	134	6	also	also	ADV
fnp-2845	134	7	higher	high	ADJ
fnp-2845	134	8	than	than	ADP
fnp-2845	134	9	in	in	ADP
fnp-2845	134	10	the	the	DET
fnp-2845	134	11	itc	itc	NOUN
fnp-2845	134	12	of	of	ADP
fnp-2845	134	13	hpcs	hpc	NOUN
fnp-2845	134	14	(	(	PUNCT
fnp-2845	134	15	p	p	X
fnp-2845	134	16	=	=	NOUN
fnp-2845	134	17	0.02	0.02	NUM
fnp-2845	134	18	)	)	PUNCT
fnp-2845	134	19	and	and	CCONJ
fnp-2845	134	20	ad	ad	NOUN
fnp-2845	134	21	cases	case	NOUN
fnp-2845	134	22	(	(	PUNCT
fnp-2845	134	23	p	p	X
fnp-2845	134	24	=	=	NOUN
fnp-2845	134	25	0.03	0.03	NUM
fnp-2845	134	26	)	)	PUNCT
fnp-2845	134	27	(	(	PUNCT
fnp-2845	134	28	fig	fig	NOUN
fnp-2845	134	29	.	.	PUNCT
fnp-2845	134	30	3a	3a	NUM
fnp-2845	134	31	)	)	PUNCT
fnp-2845	134	32	,	,	PUNCT
fnp-2845	134	33	whilst	whilst	SCONJ
fnp-2845	134	34	the	the	DET
fnp-2845	134	35	density	density	NOUN
fnp-2845	134	36	of	of	ADP
fnp-2845	134	37	total	total	NOUN
fnp-2845	134	38	(	(	PUNCT
fnp-2845	134	39	p	p	X
fnp-2845	134	40	=	=	NOUN
fnp-2845	134	41	0.04	0.04	NUM
fnp-2845	134	42	)	)	PUNCT
fnp-2845	134	43	and	and	CCONJ
fnp-2845	134	44	ramified	ramify	VERB
fnp-2845	134	45	microglia	microglia	NOUN
fnp-2845	134	46	(	(	PUNCT
fnp-2845	134	47	p	p	X
fnp-2845	134	48	=	=	NOUN
fnp-2845	134	49	0.002	0.002	NUM
fnp-2845	134	50	)	)	PUNCT
fnp-2845	134	51	were	be	AUX
fnp-2845	134	52	reduced	reduce	VERB
fnp-2845	134	53	in	in	ADP
fnp-2845	134	54	the	the	DET
fnp-2845	134	55	itc	itc	NOUN
fnp-2845	134	56	compared	compare	VERB
fnp-2845	134	57	to	to	ADP
fnp-2845	134	58	the	the	DET
fnp-2845	134	59	pmc	pmc	PROPN
fnp-2845	134	60	of	of	ADP
fnp-2845	134	61	ad	ad	NOUN
fnp-2845	134	62	cases	case	NOUN
fnp-2845	134	63	.	.	PUNCT
fnp-2845	135	1	immunofluorescent	immunofluorescent	VERB
fnp-2845	135	2	double	double	ADJ
fnp-2845	135	3	-	-	PUNCT
fnp-2845	135	4	labelling	labelling	NOUN
fnp-2845	135	5	for	for	ADP
fnp-2845	135	6	aβ	aβ	PRON
fnp-2845	135	7	and	and	CCONJ
fnp-2845	135	8	iba1	iba1	PROPN
fnp-2845	135	9	in	in	ADP
fnp-2845	135	10	the	the	DET
fnp-2845	135	11	pmc	pmc	PROPN
fnp-2845	135	12	showed	show	VERB
fnp-2845	135	13	that	that	SCONJ
fnp-2845	135	14	the	the	DET
fnp-2845	135	15	clusters	cluster	NOUN
fnp-2845	135	16	of	of	ADP
fnp-2845	135	17	activated	activated	ADJ
fnp-2845	135	18	microglia	microglia	NOUN
fnp-2845	135	19	,	,	PUNCT
fnp-2845	135	20	occurred	occur	VERB
fnp-2845	135	21	preferentially	preferentially	ADV
fnp-2845	135	22	within	within	ADP
fnp-2845	135	23	the	the	DET
fnp-2845	135	24	boundaries	boundary	NOUN
fnp-2845	135	25	of	of	ADP
fnp-2845	135	26	fibrillar	fibrillar	ADJ
fnp-2845	135	27	aβ	aβ	NOUN
fnp-2845	135	28	plaques	plaque	NOUN
fnp-2845	135	29	,	,	PUNCT
fnp-2845	135	30	with	with	ADP
fnp-2845	135	31	a	a	DET
fnp-2845	135	32	significant	significant	ADJ
fnp-2845	135	33	correlation	correlation	NOUN
fnp-2845	135	34	in	in	ADP
fnp-2845	135	35	a	a	DET
fnp-2845	135	36	combined	combine	VERB
fnp-2845	135	37	analysis	analysis	NOUN
fnp-2845	135	38	of	of	ADP
fnp-2845	135	39	control	control	NOUN
fnp-2845	135	40	and	and	CCONJ
fnp-2845	135	41	ad	ad	NOUN
fnp-2845	135	42	brains	brain	NOUN
fnp-2845	135	43	(	(	PUNCT
fnp-2845	135	44	spearman	spearman	NOUN
fnp-2845	135	45	ρ	ρ	PROPN
fnp-2845	135	46	=	=	PROPN
fnp-2845	135	47	0.54	0.54	NUM
fnp-2845	135	48	,	,	PUNCT
fnp-2845	135	49	p	p	X
fnp-2845	135	50	=	=	NOUN
fnp-2845	135	51	0.006	0.006	NUM
fnp-2845	135	52	;	;	PUNCT
fnp-2845	135	53	fig	fig	NOUN
fnp-2845	135	54	.	.	PUNCT
fnp-2845	136	1	3a	3a	NUM
fnp-2845	136	2	)	)	PUNCT
fnp-2845	136	3	.	.	PUNCT
fnp-2845	137	1	the	the	DET
fnp-2845	137	2	percentage	percentage	NOUN
fnp-2845	137	3	of	of	ADP
fnp-2845	137	4	aβ	aβ	DET
fnp-2845	137	5	plaques	plaque	NOUN
fnp-2845	137	6	associated	associate	VERB
fnp-2845	137	7	with	with	ADP
fnp-2845	137	8	a	a	DET
fnp-2845	137	9	cluster	cluster	NOUN
fnp-2845	137	10	of	of	ADP
fnp-2845	137	11	activated	activate	VERB
fnp-2845	137	12	microglia	microglia	NOUN
fnp-2845	137	13	in	in	ADP
fnp-2845	137	14	the	the	DET
fnp-2845	137	15	pmc	pmc	NOUN
fnp-2845	137	16	ranged	range	VERB
fnp-2845	137	17	from	from	ADP
fnp-2845	137	18	a	a	DET
fnp-2845	137	19	mean	mean	NOUN
fnp-2845	137	20	of	of	ADP
fnp-2845	137	21	41	41	NUM
fnp-2845	137	22	%	%	NOUN
fnp-2845	137	23	in	in	ADP
fnp-2845	137	24	controls	control	NOUN
fnp-2845	137	25	and	and	CCONJ
fnp-2845	137	26	43	43	NUM
fnp-2845	137	27	%	%	NOUN
fnp-2845	137	28	in	in	ADP
fnp-2845	137	29	ad	ad	NOUN
fnp-2845	137	30	cases	case	NOUN
fnp-2845	137	31	to	to	ADP
fnp-2845	137	32	60	60	NUM
fnp-2845	137	33	%	%	NOUN
fnp-2845	137	34	in	in	ADP
fnp-2845	137	35	hpcs	hpc	NOUN
fnp-2845	137	36	,	,	PUNCT
fnp-2845	137	37	with	with	ADP
fnp-2845	137	38	one	one	NUM
fnp-2845	137	39	control	control	NOUN
fnp-2845	137	40	(	(	PUNCT
fnp-2845	137	41	m15	m15	NOUN
fnp-2845	137	42	)	)	PUNCT
fnp-2845	137	43	,	,	PUNCT
fnp-2845	137	44	two	two	NUM
fnp-2845	137	45	hpcs	hpc	NOUN
fnp-2845	137	46	(	(	PUNCT
fnp-2845	137	47	m14	m14	NOUN
fnp-2845	137	48	and	and	CCONJ
fnp-2845	137	49	m18	m18	PROPN
fnp-2845	137	50	)	)	PUNCT
fnp-2845	137	51	,	,	PUNCT
fnp-2845	137	52	and	and	CCONJ
fnp-2845	137	53	one	one	NUM
fnp-2845	137	54	ad	ad	NOUN
fnp-2845	137	55	case	case	NOUN
fnp-2845	137	56	(	(	PUNCT
fnp-2845	137	57	m13	m13	NOUN
fnp-2845	137	58	)	)	PUNCT
fnp-2845	137	59	having	have	VERB
fnp-2845	137	60	a	a	DET
fnp-2845	137	61	higher	high	ADJ
fnp-2845	137	62	density	density	NOUN
fnp-2845	137	63	of	of	ADP
fnp-2845	137	64	microglial	microglial	ADJ
fnp-2845	137	65	clusters	cluster	NOUN
fnp-2845	137	66	than	than	ADP
fnp-2845	137	67	aβ	aβ	PRON
fnp-2845	137	68	plaques	plaque	NOUN
fnp-2845	137	69	.	.	PUNCT
fnp-2845	138	1	figure	figure	VERB
fnp-2845	138	2	2	2	NUM
fnp-2845	138	3	response	response	NOUN
fnp-2845	138	4	of	of	ADP
fnp-2845	138	5	microglia	microglia	NOUN
fnp-2845	138	6	to	to	ADP
fnp-2845	138	7	ad	ad	NOUN
fnp-2845	138	8	pathology	pathology	NOUN
fnp-2845	138	9	.	.	PUNCT
fnp-2845	139	1	a	a	X
fnp-2845	139	2	–	–	PUNCT
fnp-2845	139	3	e	e	X
fnp-2845	139	4	a	a	DET
fnp-2845	139	5	spectrum	spectrum	NOUN
fnp-2845	139	6	of	of	ADP
fnp-2845	139	7	microglial	microglial	ADJ
fnp-2845	139	8	activation	activation	NOUN
fnp-2845	139	9	can	can	AUX
fnp-2845	139	10	be	be	AUX
fnp-2845	139	11	identified	identify	VERB
fnp-2845	139	12	by	by	ADP
fnp-2845	139	13	a	a	DET
fnp-2845	139	14	series	series	NOUN
fnp-2845	139	15	of	of	ADP
fnp-2845	139	16	morphological	morphological	ADJ
fnp-2845	139	17	changes	change	NOUN
fnp-2845	139	18	including	include	VERB
fnp-2845	139	19	an	an	DET
fnp-2845	139	20	enrichment	enrichment	NOUN
fnp-2845	139	21	of	of	ADP
fnp-2845	139	22	iba1	iba1	PROPN
fnp-2845	139	23	labelling	labelling	NOUN
fnp-2845	139	24	of	of	ADP
fnp-2845	139	25	the	the	DET
fnp-2845	139	26	soma	soma	NOUN
fnp-2845	139	27	and	and	CCONJ
fnp-2845	139	28	primary	primary	ADJ
fnp-2845	139	29	processes	process	NOUN
fnp-2845	139	30	(	(	PUNCT
fnp-2845	139	31	a	a	X
fnp-2845	139	32	)	)	PUNCT
fnp-2845	139	33	,	,	PUNCT
fnp-2845	139	34	hypertrophy	hypertrophy	NOUN
fnp-2845	139	35	of	of	ADP
fnp-2845	139	36	the	the	DET
fnp-2845	139	37	primary	primary	ADJ
fnp-2845	139	38	processes	process	NOUN
fnp-2845	139	39	(	(	PUNCT
fnp-2845	139	40	b	b	NOUN
fnp-2845	139	41	)	)	PUNCT
fnp-2845	139	42	,	,	PUNCT
fnp-2845	139	43	retraction	retraction	NOUN
fnp-2845	139	44	of	of	ADP
fnp-2845	139	45	tertiary	tertiary	ADJ
fnp-2845	139	46	processes	process	NOUN
fnp-2845	139	47	±	±	NOUN
fnp-2845	139	48	the	the	DET
fnp-2845	139	49	formation	formation	NOUN
fnp-2845	139	50	of	of	ADP
fnp-2845	139	51	morphological	morphological	ADJ
fnp-2845	139	52	features	feature	NOUN
fnp-2845	139	53	consistent	consistent	ADJ
fnp-2845	139	54	with	with	ADP
fnp-2845	139	55	phagosomes	phagosome	NOUN
fnp-2845	139	56	(	(	PUNCT
fnp-2845	139	57	arrow	arrow	NOUN
fnp-2845	139	58	heads	head	NOUN
fnp-2845	139	59	)	)	PUNCT
fnp-2845	139	60	(	(	PUNCT
fnp-2845	139	61	c	c	NOUN
fnp-2845	139	62	)	)	PUNCT
fnp-2845	139	63	,	,	PUNCT
fnp-2845	139	64	further	further	ADJ
fnp-2845	139	65	retraction	retraction	NOUN
fnp-2845	139	66	of	of	ADP
fnp-2845	139	67	secondary	secondary	ADJ
fnp-2845	139	68	processes	process	NOUN
fnp-2845	139	69	(	(	PUNCT
fnp-2845	139	70	d	d	NOUN
fnp-2845	139	71	)	)	PUNCT
fnp-2845	139	72	,	,	PUNCT
fnp-2845	139	73	until	until	ADP
fnp-2845	139	74	amoeboid	amoeboid	NOUN
fnp-2845	139	75	in	in	ADP
fnp-2845	139	76	shape	shape	NOUN
fnp-2845	139	77	(	(	PUNCT
fnp-2845	139	78	e	e	NOUN
fnp-2845	139	79	)	)	PUNCT
fnp-2845	139	80	.	.	PUNCT
fnp-2845	140	1	f	f	X
fnp-2845	140	2	–	–	PUNCT
fnp-2845	140	3	h	h	PRON
fnp-2845	140	4	healthy	healthy	ADJ
fnp-2845	140	5	ramified	ramified	ADJ
fnp-2845	140	6	microglia	microglia	NOUN
fnp-2845	140	7	have	have	VERB
fnp-2845	140	8	a	a	DET
fnp-2845	140	9	small	small	ADJ
fnp-2845	140	10	,	,	PUNCT
fnp-2845	140	11	spherical	spherical	ADJ
fnp-2845	140	12	soma	soma	NOUN
fnp-2845	140	13	and	and	CCONJ
fnp-2845	140	14	thin	thin	ADJ
fnp-2845	140	15	,	,	PUNCT
fnp-2845	140	16	evenly	evenly	ADV
fnp-2845	140	17	distributed	distribute	VERB
fnp-2845	140	18	processes	process	NOUN
fnp-2845	140	19	(	(	PUNCT
fnp-2845	140	20	f	f	X
fnp-2845	140	21	)	)	PUNCT
fnp-2845	140	22	,	,	PUNCT
fnp-2845	140	23	contrasting	contrast	VERB
fnp-2845	140	24	with	with	ADP
fnp-2845	140	25	dystrophic	dystrophic	ADJ
fnp-2845	140	26	microglia	microglia	NOUN
fnp-2845	140	27	that	that	PRON
fnp-2845	140	28	have	have	AUX
fnp-2845	140	29	either	either	CCONJ
fnp-2845	140	30	deramified	deramified	ADJ
fnp-2845	140	31	and	and	CCONJ
fnp-2845	140	32	tortuous	tortuous	ADJ
fnp-2845	140	33	processes	process	NOUN
fnp-2845	140	34	(	(	PUNCT
fnp-2845	140	35	g	g	NOUN
fnp-2845	140	36	)	)	PUNCT
fnp-2845	140	37	or	or	CCONJ
fnp-2845	140	38	pseudo	pseudo	NOUN
fnp-2845	140	39	-	-	NOUN
fnp-2845	140	40	fragmentation	fragmentation	NOUN
fnp-2845	140	41	of	of	ADP
fnp-2845	140	42	processes	process	NOUN
fnp-2845	140	43	when	when	SCONJ
fnp-2845	140	44	marked	mark	VERB
fnp-2845	140	45	with	with	ADP
fnp-2845	140	46	iba1	iba1	PROPN
fnp-2845	140	47	(	(	PUNCT
fnp-2845	140	48	h	h	NOUN
fnp-2845	140	49	)	)	PUNCT
fnp-2845	140	50	.	.	PUNCT
fnp-2845	141	1	i	i	PRON
fnp-2845	141	2	–	–	PUNCT
fnp-2845	141	3	j	j	PROPN
fnp-2845	141	4	microglia	microglia	NOUN
fnp-2845	141	5	that	that	PRON
fnp-2845	141	6	form	form	VERB
fnp-2845	141	7	a	a	DET
fnp-2845	141	8	cluster	cluster	NOUN
fnp-2845	141	9	within	within	ADP
fnp-2845	141	10	the	the	DET
fnp-2845	141	11	boundary	boundary	NOUN
fnp-2845	141	12	of	of	ADP
fnp-2845	141	13	an	an	DET
fnp-2845	141	14	aβ	aβ	NOUN
fnp-2845	141	15	plaque	plaque	NOUN
fnp-2845	141	16	may	may	AUX
fnp-2845	141	17	be	be	AUX
fnp-2845	141	18	either	either	CCONJ
fnp-2845	141	19	dystrophic	dystrophic	ADJ
fnp-2845	141	20	or	or	CCONJ
fnp-2845	141	21	have	have	AUX
fnp-2845	141	22	reached	reach	VERB
fnp-2845	141	23	a	a	DET
fnp-2845	141	24	phase	phase	NOUN
fnp-2845	141	25	of	of	ADP
fnp-2845	141	26	early	early	ADJ
fnp-2845	141	27	(	(	PUNCT
fnp-2845	141	28	i	i	NOUN
fnp-2845	141	29	)	)	PUNCT
fnp-2845	141	30	or	or	CCONJ
fnp-2845	141	31	late	late	ADV
fnp-2845	141	32	/	/	SYM
fnp-2845	141	33	amoeboid	amoeboid	NOUN
fnp-2845	141	34	(	(	PUNCT
fnp-2845	141	35	j	j	NOUN
fnp-2845	141	36	)	)	PUNCT
fnp-2845	141	37	activation	activation	NOUN
fnp-2845	141	38	.	.	PUNCT
fnp-2845	142	1	k	k	X
fnp-2845	142	2	–	–	PUNCT
fnp-2845	142	3	l	l	NOUN
fnp-2845	142	4	mosaics	mosaic	NOUN
fnp-2845	142	5	of	of	ADP
fnp-2845	142	6	iba1	iba1	PROPN
fnp-2845	142	7	staining	stain	VERB
fnp-2845	142	8	demonstrating	demonstrate	VERB
fnp-2845	142	9	the	the	DET
fnp-2845	142	10	size	size	NOUN
fnp-2845	142	11	and	and	CCONJ
fnp-2845	142	12	distribution	distribution	NOUN
fnp-2845	142	13	of	of	ADP
fnp-2845	142	14	microglial	microglial	ADJ
fnp-2845	142	15	clusters	cluster	NOUN
fnp-2845	142	16	(	(	PUNCT
fnp-2845	142	17	arrows	arrow	NOUN
fnp-2845	142	18	)	)	PUNCT
fnp-2845	142	19	,	,	PUNCT
fnp-2845	142	20	defined	define	VERB
fnp-2845	142	21	as	as	ADP
fnp-2845	142	22	three	three	NUM
fnp-2845	142	23	or	or	CCONJ
fnp-2845	142	24	more	more	ADJ
fnp-2845	142	25	somata	somata	ADJ
fnp-2845	142	26	occurring	occur	VERB
fnp-2845	142	27	within	within	ADP
fnp-2845	142	28	,	,	PUNCT
fnp-2845	142	29	or	or	CCONJ
fnp-2845	142	30	touch	touch	VERB
fnp-2845	142	31	the	the	DET
fnp-2845	142	32	boundaries	boundary	NOUN
fnp-2845	142	33	of	of	ADP
fnp-2845	142	34	,	,	PUNCT
fnp-2845	142	35	a	a	DET
fnp-2845	142	36	20	20	NUM
fnp-2845	142	37	μm2	μm2	NOUN
fnp-2845	142	38	virtual	virtual	ADJ
fnp-2845	142	39	graticule	graticule	NOUN
fnp-2845	142	40	subregion	subregion	NOUN
fnp-2845	142	41	,	,	PUNCT
fnp-2845	142	42	in	in	ADP
fnp-2845	142	43	the	the	DET
fnp-2845	142	44	pmc	pmc	NOUN
fnp-2845	142	45	of	of	ADP
fnp-2845	142	46	an	an	DET
fnp-2845	142	47	hpc	hpc	PROPN
fnp-2845	142	48	(	(	PUNCT
fnp-2845	142	49	k	k	NOUN
fnp-2845	142	50	;	;	PUNCT
fnp-2845	142	51	m23	m23	NUM
fnp-2845	142	52	)	)	PUNCT
fnp-2845	142	53	and	and	CCONJ
fnp-2845	142	54	ad	ad	NOUN
fnp-2845	142	55	case	case	NOUN
fnp-2845	142	56	(	(	PUNCT
fnp-2845	142	57	l	l	NOUN
fnp-2845	142	58	;	;	PUNCT
fnp-2845	142	59	m13	m13	NUM
fnp-2845	142	60	)	)	PUNCT
fnp-2845	142	61	.	.	PUNCT
fnp-2845	143	1	scale	scale	NOUN
fnp-2845	143	2	bar	bar	NOUN
fnp-2845	143	3	in	in	ADP
fnp-2845	143	4	j	j	PROPN
fnp-2845	143	5	=	=	SYM
fnp-2845	143	6	40	40	NUM
fnp-2845	143	7	μm	μm	NOUN
fnp-2845	143	8	(	(	PUNCT
fnp-2845	143	9	a	a	PRON
fnp-2845	143	10	–	–	PUNCT
fnp-2845	143	11	j	j	NOUN
fnp-2845	143	12	)	)	PUNCT
fnp-2845	143	13	;	;	PUNCT
fnp-2845	143	14	in	in	ADP
fnp-2845	143	15	l	l	NOUN
fnp-2845	143	16	=	=	PUNCT
fnp-2845	143	17	100	100	NUM
fnp-2845	143	18	μm	μm	NOUN
fnp-2845	143	19	(	(	PUNCT
fnp-2845	143	20	k	k	X
fnp-2845	143	21	–	–	PUNCT
fnp-2845	143	22	l	l	NOUN
fnp-2845	143	23	)	)	PUNCT
fnp-2845	143	24	figure	figure	NOUN
fnp-2845	143	25	3	3	NUM
fnp-2845	143	26	characteristics	characteristic	NOUN
fnp-2845	143	27	of	of	ADP
fnp-2845	143	28	microglial	microglial	ADJ
fnp-2845	143	29	clustering	clustering	NOUN
fnp-2845	143	30	in	in	ADP
fnp-2845	143	31	the	the	DET
fnp-2845	143	32	pmc	pmc	PROPN
fnp-2845	143	33	.	.	PUNCT
fnp-2845	144	1	a	a	DET
fnp-2845	144	2	the	the	DET
fnp-2845	144	3	density	density	NOUN
fnp-2845	144	4	of	of	ADP
fnp-2845	144	5	microglial	microglial	ADJ
fnp-2845	144	6	clusters	cluster	NOUN
fnp-2845	144	7	was	be	AUX
fnp-2845	144	8	significantly	significantly	ADV
fnp-2845	144	9	greater	great	ADJ
fnp-2845	144	10	in	in	ADP
fnp-2845	144	11	the	the	DET
fnp-2845	144	12	pmc	pmc	PROPN
fnp-2845	144	13	of	of	ADP
fnp-2845	144	14	hpcs	hpc	NOUN
fnp-2845	144	15	and	and	CCONJ
fnp-2845	144	16	ad	ad	NOUN
fnp-2845	144	17	cases	case	NOUN
fnp-2845	144	18	compared	compare	VERB
fnp-2845	144	19	to	to	ADP
fnp-2845	144	20	controls	control	NOUN
fnp-2845	144	21	.	.	PUNCT
fnp-2845	145	1	b	b	PRON
fnp-2845	145	2	microglial	microglial	ADJ
fnp-2845	145	3	clusters	cluster	NOUN
fnp-2845	145	4	were	be	AUX
fnp-2845	145	5	more	more	ADV
fnp-2845	145	6	frequently	frequently	ADV
fnp-2845	145	7	associated	associate	VERB
fnp-2845	145	8	with	with	ADP
fnp-2845	145	9	fibrillar	fibrillar	ADJ
fnp-2845	145	10	neuritic	neuritic	ADJ
fnp-2845	145	11	plaques	plaque	NOUN
fnp-2845	145	12	in	in	ADP
fnp-2845	145	13	a	a	DET
fnp-2845	145	14	combined	combine	VERB
fnp-2845	145	15	group	group	NOUN
fnp-2845	145	16	analysis	analysis	NOUN
fnp-2845	145	17	;	;	PUNCT
fnp-2845	145	18	spearman	spearman	NOUN
fnp-2845	145	19	ρ	ρ	PROPN
fnp-2845	145	20	=	=	PROPN
fnp-2845	145	21	0.54	0.54	NUM
fnp-2845	145	22	,	,	PUNCT
fnp-2845	145	23	p	p	X
fnp-2845	145	24	=	=	NOUN
fnp-2845	145	25	0.006	0.006	NUM
fnp-2845	145	26	.	.	PUNCT
fnp-2845	146	1	†significantly	†significantly	ADV
fnp-2845	146	2	reduced	reduce	VERB
fnp-2845	146	3	compared	compare	VERB
fnp-2845	146	4	to	to	ADP
fnp-2845	146	5	pmc	pmc	PROPN
fnp-2845	146	6	of	of	ADP
fnp-2845	146	7	hpcs	hpc	NOUN
fnp-2845	146	8	;	;	PUNCT
fnp-2845	146	9	‡significantly	‡significantly	ADV
fnp-2845	146	10	reduced	reduce	VERB
fnp-2845	146	11	compared	compare	VERB
fnp-2845	146	12	to	to	ADP
fnp-2845	146	13	pmc	pmc	PROPN
fnp-2845	146	14	of	of	ADP
fnp-2845	146	15	ad	ad	NOUN
fnp-2845	146	16	cases	case	NOUN
fnp-2845	146	17	.	.	PUNCT
fnp-2845	147	1	*	*	PUNCT
fnp-2845	147	2	†‡p<0.05	†‡p<0.05	NOUN
fnp-2845	147	3	.	.	PUNCT
fnp-2845	147	4	table	table	NOUN
fnp-2845	147	5	4	4	NUM
fnp-2845	147	6	.	.	PUNCT
fnp-2845	148	1	quantification	quantification	NOUN
fnp-2845	148	2	of	of	ADP
fnp-2845	148	3	the	the	DET
fnp-2845	148	4	morphological	morphological	ADJ
fnp-2845	148	5	subtypes	subtype	NOUN
fnp-2845	148	6	of	of	ADP
fnp-2845	148	7	microglia	microglia	NOUN
fnp-2845	148	8	in	in	ADP
fnp-2845	148	9	the	the	DET
fnp-2845	148	10	primary	primary	ADJ
fnp-2845	148	11	motor	motor	PROPN
fnp-2845	148	12	cortexa	cortexa	PROPN
fnp-2845	148	13	acells	acells	PROPN
fnp-2845	148	14	/	/	SYM
fnp-2845	148	15	mm2	mm2	PROPN
fnp-2845	148	16	;	;	PUNCT
fnp-2845	148	17	mean	mean	ADJ
fnp-2845	148	18	±	±	NUM
fnp-2845	148	19	standard	standard	ADJ
fnp-2845	148	20	deviation	deviation	NOUN
fnp-2845	148	21	.	.	PUNCT
fnp-2845	149	1	banova	banova	PROPN
fnp-2845	149	2	results	result	NOUN
fnp-2845	149	3	;	;	PUNCT
fnp-2845	149	4	see	see	VERB
fnp-2845	149	5	text	text	NOUN
fnp-2845	149	6	for	for	ADP
fnp-2845	149	7	p	p	NOUN
fnp-2845	149	8	-	-	PUNCT
fnp-2845	149	9	values	value	NOUN
fnp-2845	149	10	of	of	ADP
fnp-2845	149	11	pairwise	pairwise	NOUN
fnp-2845	149	12	comparisons	comparison	NOUN
fnp-2845	149	13	of	of	ADP
fnp-2845	149	14	microglial	microglial	ADJ
fnp-2845	149	15	clusters	cluster	NOUN
fnp-2845	149	16	.	.	PUNCT
fnp-2845	150	1	a	a	DET
fnp-2845	150	2	graded	grade	VERB
fnp-2845	150	3	extent	extent	NOUN
fnp-2845	150	4	of	of	ADP
fnp-2845	150	5	neuritic	neuritic	ADJ
fnp-2845	150	6	tau	tau	PROPN
fnp-2845	150	7	pathology	pathology	NOUN
fnp-2845	150	8	and	and	CCONJ
fnp-2845	150	9	clustering	clustering	NOUN
fnp-2845	150	10	of	of	ADP
fnp-2845	150	11	microglia	microglia	NOUN
fnp-2845	150	12	occurs	occur	VERB
fnp-2845	150	13	within	within	ADP
fnp-2845	150	14	nascent	nascent	NOUN
fnp-2845	150	15	aβ	aβ	NOUN
fnp-2845	150	16	plaques	plaque	NOUN
fnp-2845	150	17	,	,	PUNCT
fnp-2845	150	18	with	with	ADP
fnp-2845	150	19	the	the	DET
fnp-2845	150	20	persistence	persistence	NOUN
fnp-2845	150	21	of	of	ADP
fnp-2845	150	22	dystrophic	dystrophic	ADJ
fnp-2845	150	23	neurites	neurite	NOUN
fnp-2845	150	24	and	and	CCONJ
fnp-2845	150	25	the	the	DET
fnp-2845	150	26	loss	loss	NOUN
fnp-2845	150	27	of	of	ADP
fnp-2845	150	28	iba1	iba1	PROPN
fnp-2845	150	29	-	-	PUNCT
fnp-2845	150	30	immunoreactivity	immunoreactivity	PROPN
fnp-2845	150	31	and	and	CCONJ
fnp-2845	150	32	aβ	aβ	NOUN
fnp-2845	150	33	-	-	PUNCT
fnp-2845	150	34	immunoreactivity	immunoreactivity	NOUN
fnp-2845	150	35	occurring	occur	VERB
fnp-2845	150	36	in	in	ADP
fnp-2845	150	37	established	establish	VERB
fnp-2845	150	38	neuritic	neuritic	ADJ
fnp-2845	150	39	plaques	plaque	NOUN
fnp-2845	150	40	all	all	PRON
fnp-2845	150	41	of	of	ADP
fnp-2845	150	42	the	the	DET
fnp-2845	150	43	aβ	aβ	NOUN
fnp-2845	150	44	plaques	plaque	NOUN
fnp-2845	150	45	examined	examine	VERB
fnp-2845	150	46	in	in	ADP
fnp-2845	150	47	the	the	DET
fnp-2845	150	48	itc	itc	PROPN
fnp-2845	150	49	,	,	PUNCT
fnp-2845	150	50	and	and	CCONJ
fnp-2845	150	51	a	a	DET
fnp-2845	150	52	majority	majority	NOUN
fnp-2845	150	53	in	in	ADP
fnp-2845	150	54	the	the	DET
fnp-2845	150	55	pmc	pmc	PROPN
fnp-2845	150	56	,	,	PUNCT
fnp-2845	150	57	contained	contain	VERB
fnp-2845	150	58	dns	dns	NOUN
fnp-2845	150	59	.	.	PUNCT
fnp-2845	151	1	however	however	ADV
fnp-2845	151	2	,	,	PUNCT
fnp-2845	151	3	the	the	DET
fnp-2845	151	4	extent	extent	NOUN
fnp-2845	151	5	of	of	ADP
fnp-2845	151	6	the	the	DET
fnp-2845	151	7	accumulated	accumulate	VERB
fnp-2845	151	8	neuritic	neuritic	ADJ
fnp-2845	151	9	tau	tau	PROPN
fnp-2845	151	10	pathology	pathology	NOUN
fnp-2845	151	11	within	within	ADP
fnp-2845	151	12	each	each	DET
fnp-2845	151	13	plaque	plaque	NOUN
fnp-2845	151	14	was	be	AUX
fnp-2845	151	15	lower	low	ADJ
fnp-2845	151	16	in	in	ADP
fnp-2845	151	17	the	the	DET
fnp-2845	151	18	pmc	pmc	PROPN
fnp-2845	151	19	(	(	PUNCT
fnp-2845	151	20	fig	fig	NOUN
fnp-2845	151	21	.	.	PUNCT
fnp-2845	151	22	4a	4a	NOUN
fnp-2845	151	23	)	)	PUNCT
fnp-2845	151	24	than	than	ADP
fnp-2845	151	25	the	the	DET
fnp-2845	151	26	itc	itc	NOUN
fnp-2845	151	27	of	of	ADP
fnp-2845	151	28	the	the	DET
fnp-2845	151	29	same	same	ADJ
fnp-2845	151	30	case	case	NOUN
fnp-2845	151	31	(	(	PUNCT
fnp-2845	151	32	fig	fig	NOUN
fnp-2845	151	33	.	.	PUNCT
fnp-2845	152	1	4b	4b	PROPN
fnp-2845	152	2	)	)	PUNCT
fnp-2845	152	3	.	.	PUNCT
fnp-2845	153	1	both	both	DET
fnp-2845	153	2	aβ	aβ	DET
fnp-2845	153	3	deposits	deposit	NOUN
fnp-2845	153	4	and	and	CCONJ
fnp-2845	153	5	globular	globular	ADJ
fnp-2845	153	6	dns	dns	NOUN
fnp-2845	153	7	were	be	AUX
fnp-2845	153	8	seen	see	VERB
fnp-2845	153	9	perivascularly	perivascularly	ADV
fnp-2845	153	10	(	(	PUNCT
fnp-2845	153	11	fig	fig	NOUN
fnp-2845	153	12	.	.	PUNCT
fnp-2845	154	1	4c	4c	NOUN
fnp-2845	154	2	)	)	PUNCT
fnp-2845	154	3	,	,	PUNCT
fnp-2845	154	4	consistent	consistent	ADJ
fnp-2845	154	5	with	with	ADP
fnp-2845	154	6	previous	previous	ADJ
fnp-2845	154	7	observations	observation	NOUN
fnp-2845	154	8	(	(	PUNCT
fnp-2845	154	9	39	39	NUM
fnp-2845	154	10	)	)	PUNCT
fnp-2845	154	11	.	.	PUNCT
fnp-2845	155	1	the	the	DET
fnp-2845	155	2	density	density	NOUN
fnp-2845	155	3	of	of	ADP
fnp-2845	155	4	dns	dns	NOUN
fnp-2845	155	5	was	be	AUX
fnp-2845	155	6	greatest	great	ADJ
fnp-2845	155	7	in	in	ADP
fnp-2845	155	8	the	the	DET
fnp-2845	155	9	itc	itc	NOUN
fnp-2845	155	10	of	of	ADP
fnp-2845	155	11	ad	ad	NOUN
fnp-2845	155	12	cases	case	NOUN
fnp-2845	155	13	(	(	PUNCT
fnp-2845	155	14	fig	fig	NOUN
fnp-2845	155	15	.	.	PUNCT
fnp-2845	156	1	4c	4c	NOUN
fnp-2845	156	2	)	)	PUNCT
fnp-2845	156	3	,	,	PUNCT
fnp-2845	156	4	which	which	PRON
fnp-2845	156	5	also	also	ADV
fnp-2845	156	6	had	have	VERB
fnp-2845	156	7	the	the	DET
fnp-2845	156	8	highest	high	ADJ
fnp-2845	156	9	density	density	NOUN
fnp-2845	156	10	of	of	ADP
fnp-2845	156	11	remnant	remnant	ADJ
fnp-2845	156	12	plaques	plaque	NOUN
fnp-2845	156	13	characterised	characterise	VERB
fnp-2845	156	14	by	by	ADP
fnp-2845	156	15	accumulations	accumulation	NOUN
fnp-2845	156	16	of	of	ADP
fnp-2845	156	17	dns	dns	NOUN
fnp-2845	156	18	associated	associate	VERB
fnp-2845	156	19	with	with	ADP
fnp-2845	156	20	weak	weak	ADJ
fnp-2845	156	21	or	or	CCONJ
fnp-2845	156	22	absent	absent	ADJ
fnp-2845	156	23	aβ	aβ	NOUN
fnp-2845	156	24	-	-	PUNCT
fnp-2845	156	25	immunoreactivity	immunoreactivity	NOUN
fnp-2845	156	26	(	(	PUNCT
fnp-2845	156	27	fig	fig	NOUN
fnp-2845	156	28	.	.	PUNCT
fnp-2845	157	1	4d	4d	NUM
fnp-2845	157	2	)	)	PUNCT
fnp-2845	157	3	.	.	PUNCT
fnp-2845	158	1	in	in	ADP
fnp-2845	158	2	the	the	DET
fnp-2845	158	3	itc	itc	PROPN
fnp-2845	158	4	a	a	DET
fnp-2845	158	5	diffuse	diffuse	PROPN
fnp-2845	158	6	lattice	lattice	NOUN
fnp-2845	158	7	of	of	ADP
fnp-2845	158	8	elongated	elongate	VERB
fnp-2845	158	9	nts	nt	NOUN
fnp-2845	158	10	occurred	occur	VERB
fnp-2845	158	11	throughout	throughout	ADP
fnp-2845	158	12	the	the	DET
fnp-2845	158	13	neuropil	neuropil	NOUN
fnp-2845	158	14	and	and	CCONJ
fnp-2845	158	15	independently	independently	ADV
fnp-2845	158	16	of	of	ADP
fnp-2845	158	17	aβ	aβ	DET
fnp-2845	158	18	plaques	plaque	NOUN
fnp-2845	158	19	(	(	PUNCT
fnp-2845	158	20	fig	fig	NOUN
fnp-2845	158	21	.	.	PUNCT
fnp-2845	159	1	4e	4e	NOUN
fnp-2845	159	2	)	)	PUNCT
fnp-2845	159	3	.	.	PUNCT
fnp-2845	160	1	dns	dns	NOUN
fnp-2845	160	2	appeared	appear	VERB
fnp-2845	160	3	radially	radially	ADV
fnp-2845	160	4	projecting	project	VERB
fnp-2845	160	5	from	from	ADP
fnp-2845	160	6	aβ	aβ	DET
fnp-2845	160	7	plaques	plaque	NOUN
fnp-2845	160	8	(	(	PUNCT
fnp-2845	160	9	fig	fig	NOUN
fnp-2845	160	10	.	.	PUNCT
fnp-2845	161	1	4e	4e	NOUN
fnp-2845	161	2	)	)	PUNCT
fnp-2845	162	1	and	and	CCONJ
fnp-2845	162	2	showed	show	VERB
fnp-2845	162	3	either	either	CCONJ
fnp-2845	162	4	elongated	elongate	VERB
fnp-2845	162	5	or	or	CCONJ
fnp-2845	162	6	globular	globular	ADJ
fnp-2845	162	7	morphology	morphology	NOUN
fnp-2845	162	8	(	(	PUNCT
fnp-2845	162	9	fig	fig	NOUN
fnp-2845	162	10	.	.	PUNCT
fnp-2845	163	1	5a	5a	NUM
fnp-2845	163	2	)	)	PUNCT
fnp-2845	163	3	.	.	PUNCT
fnp-2845	164	1	hoechst	hoechst	ADJ
fnp-2845	164	2	dye	dye	NOUN
fnp-2845	164	3	marked	mark	VERB
fnp-2845	164	4	cell	cell	NOUN
fnp-2845	164	5	nuclei	nucleus	NOUN
fnp-2845	164	6	around	around	ADP
fnp-2845	164	7	the	the	DET
fnp-2845	164	8	periphery	periphery	NOUN
fnp-2845	164	9	of	of	ADP
fnp-2845	164	10	aβ	aβ	NOUN
fnp-2845	164	11	plaques	plaque	NOUN
fnp-2845	164	12	and	and	CCONJ
fnp-2845	164	13	also	also	ADV
fnp-2845	164	14	partly	partly	ADV
fnp-2845	164	15	stained	stain	VERB
fnp-2845	164	16	the	the	DET
fnp-2845	164	17	fibrillar	fibrillar	ADJ
fnp-2845	164	18	deposits	deposit	NOUN
fnp-2845	164	19	of	of	ADP
fnp-2845	164	20	aβ	aβ	PROPN
fnp-2845	164	21	(	(	PUNCT
fnp-2845	164	22	fig	fig	NOUN
fnp-2845	164	23	.	.	PUNCT
fnp-2845	165	1	5a	5a	NUM
fnp-2845	165	2	)	)	PUNCT
fnp-2845	165	3	.	.	PUNCT
fnp-2845	166	1	hoechst	hoechst	PROPN
fnp-2845	166	2	has	have	AUX
fnp-2845	166	3	previously	previously	ADV
fnp-2845	166	4	been	be	AUX
fnp-2845	166	5	reported	report	VERB
fnp-2845	166	6	to	to	PART
fnp-2845	166	7	stain	stain	VERB
fnp-2845	166	8	aβ	aβ	DET
fnp-2845	166	9	plaques	plaque	NOUN
fnp-2845	166	10	in	in	ADP
fnp-2845	166	11	transgenic	transgenic	NOUN
fnp-2845	166	12	mice	mouse	NOUN
fnp-2845	166	13	(	(	PUNCT
fnp-2845	166	14	40	40	NUM
fnp-2845	166	15	)	)	PUNCT
fnp-2845	166	16	.	.	PUNCT
fnp-2845	167	1	immunofluorescent	immunofluorescent	VERB
fnp-2845	167	2	double	double	ADJ
fnp-2845	167	3	-	-	PUNCT
fnp-2845	167	4	labelling	labelling	NOUN
fnp-2845	167	5	showed	show	VERB
fnp-2845	167	6	no	no	DET
fnp-2845	167	7	colocalisation	colocalisation	NOUN
fnp-2845	167	8	of	of	ADP
fnp-2845	167	9	aβ	aβ	NOUN
fnp-2845	167	10	and	and	CCONJ
fnp-2845	167	11	ttau	ttau	PRON
fnp-2845	167	12	(	(	PUNCT
fnp-2845	167	13	fig	fig	NOUN
fnp-2845	167	14	.	.	PUNCT
fnp-2845	168	1	5b	5b	NUM
fnp-2845	168	2	)	)	PUNCT
fnp-2845	168	3	.	.	PUNCT
fnp-2845	169	1	figure	figure	VERB
fnp-2845	169	2	4	4	NUM
fnp-2845	169	3	immunofluorescent	immunofluorescent	VERB
fnp-2845	169	4	double	double	ADJ
fnp-2845	169	5	-	-	PUNCT
fnp-2845	169	6	labelling	labelling	NOUN
fnp-2845	169	7	for	for	ADP
fnp-2845	169	8	aβ	aβ	PRON
fnp-2845	169	9	and	and	CCONJ
fnp-2845	169	10	ttau	ttau	VERB
fnp-2845	169	11	.	.	PUNCT
fnp-2845	170	1	a	a	DET
fnp-2845	170	2	–	–	PUNCT
fnp-2845	170	3	c	c	X
fnp-2845	170	4	the	the	DET
fnp-2845	170	5	majority	majority	NOUN
fnp-2845	170	6	of	of	ADP
fnp-2845	170	7	aβ	aβ	DET
fnp-2845	170	8	plaques	plaque	NOUN
fnp-2845	170	9	examined	examine	VERB
fnp-2845	170	10	here	here	ADV
fnp-2845	170	11	were	be	AUX
fnp-2845	170	12	associated	associate	VERB
fnp-2845	170	13	tau	tau	ADJ
fnp-2845	170	14	-	-	PUNCT
fnp-2845	170	15	positive	positive	ADJ
fnp-2845	170	16	dystrophic	dystrophic	ADJ
fnp-2845	170	17	neurites	neurite	NOUN
fnp-2845	170	18	,	,	PUNCT
fnp-2845	170	19	with	with	ADP
fnp-2845	170	20	a	a	DET
fnp-2845	170	21	clear	clear	ADJ
fnp-2845	170	22	gradation	gradation	NOUN
fnp-2845	170	23	visible	visible	ADJ
fnp-2845	170	24	between	between	ADP
fnp-2845	170	25	the	the	DET
fnp-2845	170	26	pmc	pmc	PROPN
fnp-2845	170	27	(	(	PUNCT
fnp-2845	170	28	a	a	NOUN
fnp-2845	170	29	)	)	PUNCT
fnp-2845	170	30	and	and	CCONJ
fnp-2845	170	31	itc	itc	PROPN
fnp-2845	170	32	(	(	PUNCT
fnp-2845	170	33	b	b	NOUN
fnp-2845	170	34	)	)	PUNCT
fnp-2845	170	35	in	in	ADP
fnp-2845	170	36	controls	control	NOUN
fnp-2845	170	37	(	(	PUNCT
fnp-2845	170	38	m01	m01	NUM
fnp-2845	170	39	pictured	picture	VERB
fnp-2845	170	40	in	in	ADP
fnp-2845	170	41	a	a	PRON
fnp-2845	170	42	and	and	CCONJ
fnp-2845	170	43	b	b	NOUN
fnp-2845	170	44	)	)	PUNCT
fnp-2845	170	45	and	and	CCONJ
fnp-2845	170	46	ad	ad	NOUN
fnp-2845	170	47	cases	case	NOUN
fnp-2845	170	48	(	(	PUNCT
fnp-2845	170	49	itc	itc	NOUN
fnp-2845	170	50	of	of	ADP
fnp-2845	170	51	m09	m09	NOUN
fnp-2845	170	52	pictured	picture	VERB
fnp-2845	170	53	in	in	ADP
fnp-2845	170	54	c	c	NOUN
fnp-2845	170	55	)	)	PUNCT
fnp-2845	170	56	.	.	PUNCT
fnp-2845	171	1	ad	ad	NOUN
fnp-2845	171	2	cases	case	NOUN
fnp-2845	171	3	had	have	VERB
fnp-2845	171	4	the	the	DET
fnp-2845	171	5	most	most	ADV
fnp-2845	171	6	extensive	extensive	ADJ
fnp-2845	171	7	build	build	NOUN
fnp-2845	171	8	-	-	PUNCT
fnp-2845	171	9	up	up	NOUN
fnp-2845	171	10	of	of	ADP
fnp-2845	171	11	dns	dns	NOUN
fnp-2845	171	12	in	in	ADP
fnp-2845	171	13	fibrillar	fibrillar	ADJ
fnp-2845	171	14	and	and	CCONJ
fnp-2845	171	15	dense	dense	ADV
fnp-2845	171	16	-	-	PUNCT
fnp-2845	171	17	cored	core	VERB
fnp-2845	171	18	plaques	plaque	NOUN
fnp-2845	171	19	,	,	PUNCT
fnp-2845	171	20	as	as	ADV
fnp-2845	171	21	well	well	ADV
fnp-2845	171	22	as	as	ADP
fnp-2845	171	23	perivascular	perivascular	ADJ
fnp-2845	171	24	(	(	PUNCT
fnp-2845	171	25	capillary	capillary	ADJ
fnp-2845	171	26	)	)	PUNCT
fnp-2845	171	27	aβ	aβ	PRON
fnp-2845	171	28	deposits	deposit	NOUN
fnp-2845	171	29	(	(	PUNCT
fnp-2845	171	30	c	c	NOUN
fnp-2845	171	31	)	)	PUNCT
fnp-2845	171	32	.	.	PUNCT
fnp-2845	172	1	d	d	PRON
fnp-2845	172	2	remnant	remnant	ADJ
fnp-2845	172	3	plaques	plaque	NOUN
fnp-2845	172	4	(	(	PUNCT
fnp-2845	172	5	arrows	arrow	NOUN
fnp-2845	172	6	)	)	PUNCT
fnp-2845	172	7	are	be	AUX
fnp-2845	172	8	characterised	characterise	VERB
fnp-2845	172	9	by	by	ADP
fnp-2845	172	10	absent	absent	ADJ
fnp-2845	172	11	or	or	CCONJ
fnp-2845	172	12	weak	weak	ADJ
fnp-2845	172	13	aβ	aβ	NOUN
fnp-2845	172	14	staining	stain	VERB
fnp-2845	172	15	and	and	CCONJ
fnp-2845	172	16	dense	dense	ADJ
fnp-2845	172	17	accumulations	accumulation	NOUN
fnp-2845	172	18	of	of	ADP
fnp-2845	172	19	tau	tau	PROPN
fnp-2845	172	20	pathology	pathology	NOUN
fnp-2845	172	21	and	and	CCONJ
fnp-2845	172	22	were	be	AUX
fnp-2845	172	23	much	much	ADV
fnp-2845	172	24	more	more	ADV
fnp-2845	172	25	common	common	ADJ
fnp-2845	172	26	in	in	ADP
fnp-2845	172	27	the	the	DET
fnp-2845	172	28	itc	itc	PROPN
fnp-2845	172	29	than	than	ADP
fnp-2845	172	30	the	the	DET
fnp-2845	172	31	pmc	pmc	PROPN
fnp-2845	172	32	(	(	PUNCT
fnp-2845	172	33	also	also	ADV
fnp-2845	172	34	seen	see	VERB
fnp-2845	172	35	in	in	ADP
fnp-2845	172	36	b	b	NOUN
fnp-2845	172	37	)	)	PUNCT
fnp-2845	172	38	.	.	PUNCT
fnp-2845	173	1	e	e	X
fnp-2845	173	2	severely	severely	ADV
fnp-2845	173	3	affected	affect	VERB
fnp-2845	173	4	regions	region	NOUN
fnp-2845	173	5	of	of	ADP
fnp-2845	173	6	the	the	DET
fnp-2845	173	7	ad	ad	NOUN
fnp-2845	173	8	brain	brain	NOUN
fnp-2845	173	9	,	,	PUNCT
fnp-2845	173	10	such	such	ADJ
fnp-2845	173	11	as	as	ADP
fnp-2845	173	12	the	the	DET
fnp-2845	173	13	itc	itc	PROPN
fnp-2845	173	14	,	,	PUNCT
fnp-2845	173	15	showed	show	VERB
fnp-2845	173	16	a	a	DET
fnp-2845	173	17	diffuse	diffuse	ADJ
fnp-2845	173	18	network	network	NOUN
fnp-2845	173	19	of	of	ADP
fnp-2845	173	20	elongated	elongate	VERB
fnp-2845	173	21	nts	nt	NOUN
fnp-2845	173	22	throughout	throughout	ADP
fnp-2845	173	23	the	the	DET
fnp-2845	173	24	parenchyma	parenchyma	NOUN
fnp-2845	173	25	as	as	SCONJ
fnp-2845	173	26	well	well	ADV
fnp-2845	173	27	radially	radially	ADV
fnp-2845	173	28	projecting	project	VERB
fnp-2845	173	29	dns	dns	PROPN
fnp-2845	173	30	.	.	PUNCT
fnp-2845	174	1	scale	scale	NOUN
fnp-2845	174	2	bar	bar	NOUN
fnp-2845	174	3	=	=	PUNCT
fnp-2845	174	4	20	20	NUM
fnp-2845	174	5	μm	μm	NOUN
fnp-2845	174	6	(	(	PUNCT
fnp-2845	174	7	a	a	DET
fnp-2845	174	8	–	–	PUNCT
fnp-2845	174	9	c	c	NOUN
fnp-2845	174	10	)	)	PUNCT
fnp-2845	174	11	,	,	PUNCT
fnp-2845	174	12	60	60	NUM
fnp-2845	174	13	μm	μm	NOUN
fnp-2845	174	14	(	(	PUNCT
fnp-2845	174	15	d	d	NOUN
fnp-2845	174	16	)	)	PUNCT
fnp-2845	174	17	,	,	PUNCT
fnp-2845	174	18	40	40	NUM
fnp-2845	174	19	μm	μm	NOUN
fnp-2845	174	20	(	(	PUNCT
fnp-2845	174	21	e	e	NOUN
fnp-2845	174	22	)	)	PUNCT
fnp-2845	174	23	figure	figure	NOUN
fnp-2845	174	24	5	5	NUM
fnp-2845	174	25	high	high	ADJ
fnp-2845	174	26	power	power	NOUN
fnp-2845	174	27	image	image	NOUN
fnp-2845	174	28	of	of	ADP
fnp-2845	174	29	an	an	DET
fnp-2845	174	30	aβ	aβ	NOUN
fnp-2845	174	31	plaque	plaque	NOUN
fnp-2845	174	32	in	in	ADP
fnp-2845	174	33	ad	ad	NOUN
fnp-2845	174	34	.	.	PUNCT
fnp-2845	175	1	a	a	DET
fnp-2845	175	2	image	image	NOUN
fnp-2845	175	3	panel	panel	NOUN
fnp-2845	175	4	showing	show	VERB
fnp-2845	175	5	a	a	DET
fnp-2845	175	6	fibrillar	fibrillar	ADJ
fnp-2845	175	7	neuritic	neuritic	ADJ
fnp-2845	175	8	plaque	plaque	NOUN
fnp-2845	175	9	in	in	ADP
fnp-2845	175	10	an	an	DET
fnp-2845	175	11	ad	ad	NOUN
fnp-2845	175	12	case	case	NOUN
fnp-2845	175	13	(	(	PUNCT
fnp-2845	175	14	m03	m03	NOUN
fnp-2845	175	15	)	)	PUNCT
fnp-2845	175	16	with	with	ADP
fnp-2845	175	17	globular	globular	ADJ
fnp-2845	175	18	and	and	CCONJ
fnp-2845	175	19	threadlike	threadlike	NOUN
fnp-2845	175	20	dns	dns	NOUN
fnp-2845	175	21	distributed	distribute	VERB
fnp-2845	175	22	throughout	throughout	ADP
fnp-2845	175	23	the	the	DET
fnp-2845	175	24	plaque	plaque	NOUN
fnp-2845	175	25	,	,	PUNCT
fnp-2845	175	26	which	which	PRON
fnp-2845	175	27	is	be	AUX
fnp-2845	175	28	also	also	ADV
fnp-2845	175	29	surrounded	surround	VERB
fnp-2845	175	30	by	by	ADP
fnp-2845	175	31	a	a	DET
fnp-2845	175	32	network	network	NOUN
fnp-2845	175	33	of	of	ADP
fnp-2845	175	34	nts	nt	NOUN
fnp-2845	175	35	(	(	PUNCT
fnp-2845	175	36	dotted	dotted	PROPN
fnp-2845	175	37	box	box	PROPN
fnp-2845	175	38	in	in	ADP
fnp-2845	175	39	merged	merged	ADJ
fnp-2845	175	40	image	image	NOUN
fnp-2845	175	41	demonstrates	demonstrate	VERB
fnp-2845	175	42	roi	roi	NOUN
fnp-2845	175	43	shown	show	VERB
fnp-2845	175	44	in	in	ADP
fnp-2845	175	45	b	b	NOUN
fnp-2845	175	46	)	)	PUNCT
fnp-2845	175	47	.	.	PUNCT
fnp-2845	176	1	hoechst	hoechst	ADJ
fnp-2845	176	2	staining	stain	VERB
fnp-2845	176	3	labelled	label	VERB
fnp-2845	176	4	cell	cell	NOUN
fnp-2845	176	5	nuclei	nucleus	NOUN
fnp-2845	176	6	around	around	ADP
fnp-2845	176	7	the	the	DET
fnp-2845	176	8	periphery	periphery	NOUN
fnp-2845	176	9	of	of	ADP
fnp-2845	176	10	the	the	DET
fnp-2845	176	11	plaque	plaque	NOUN
fnp-2845	176	12	as	as	ADV
fnp-2845	176	13	well	well	ADV
fnp-2845	176	14	as	as	ADP
fnp-2845	176	15	the	the	DET
fnp-2845	176	16	fibrillar	fibrillar	ADJ
fnp-2845	176	17	aβ	aβ	NOUN
fnp-2845	176	18	component	component	NOUN
fnp-2845	176	19	inside	inside	ADP
fnp-2845	176	20	the	the	DET
fnp-2845	176	21	plaque	plaque	NOUN
fnp-2845	176	22	.	.	PUNCT
fnp-2845	177	1	b	b	X
fnp-2845	177	2	colocalisation	colocalisation	NOUN
fnp-2845	177	3	study	study	NOUN
fnp-2845	177	4	showed	show	VERB
fnp-2845	177	5	no	no	DET
fnp-2845	177	6	coincidence	coincidence	NOUN
fnp-2845	177	7	aβ	aβ	NOUN
fnp-2845	177	8	and	and	CCONJ
fnp-2845	177	9	ttau	ttau	AUX
fnp-2845	177	10	staining	stain	VERB
fnp-2845	177	11	in	in	ADP
fnp-2845	177	12	any	any	PRON
fnp-2845	177	13	of	of	ADP
fnp-2845	177	14	the	the	DET
fnp-2845	177	15	sections	section	NOUN
fnp-2845	177	16	examined	examine	VERB
fnp-2845	177	17	here	here	ADV
fnp-2845	177	18	(	(	PUNCT
fnp-2845	177	19	dotted	dotted	ADJ
fnp-2845	177	20	line	line	NOUN
fnp-2845	177	21	represents	represent	VERB
fnp-2845	177	22	a	a	DET
fnp-2845	177	23	6.5	6.5	NUM
fnp-2845	177	24	μm	μm	NOUN
fnp-2845	177	25	length	length	NOUN
fnp-2845	177	26	along	along	ADP
fnp-2845	177	27	which	which	PRON
fnp-2845	177	28	pixel	pixel	PROPN
fnp-2845	177	29	intensities	intensity	NOUN
fnp-2845	177	30	have	have	AUX
fnp-2845	177	31	been	be	AUX
fnp-2845	177	32	compared	compare	VERB
fnp-2845	177	33	in	in	ADP
fnp-2845	177	34	this	this	DET
fnp-2845	177	35	exemplar	exemplar	ADJ
fnp-2845	177	36	roi	roi	NOUN
fnp-2845	177	37	)	)	PUNCT
fnp-2845	177	38	.	.	PUNCT
fnp-2845	178	1	scale	scale	NOUN
fnp-2845	178	2	bar	bar	NOUN
fnp-2845	178	3	=	=	PUNCT
fnp-2845	178	4	20	20	NUM
fnp-2845	178	5	μm	μm	NOUN
fnp-2845	178	6	(	(	PUNCT
fnp-2845	178	7	a	a	NOUN
fnp-2845	178	8	)	)	PUNCT
fnp-2845	178	9	microglia	microglia	ADJ
fnp-2845	178	10	cell	cell	NOUN
fnp-2845	178	11	processes	process	NOUN
fnp-2845	178	12	exhibiting	exhibit	VERB
fnp-2845	178	13	evidence	evidence	NOUN
fnp-2845	178	14	of	of	ADP
fnp-2845	178	15	phagocytic	phagocytic	ADJ
fnp-2845	178	16	activity	activity	NOUN
fnp-2845	178	17	are	be	AUX
fnp-2845	178	18	interspersed	intersperse	VERB
fnp-2845	178	19	around	around	ADP
fnp-2845	178	20	the	the	DET
fnp-2845	178	21	periphery	periphery	NOUN
fnp-2845	178	22	and	and	CCONJ
fnp-2845	178	23	core	core	NOUN
fnp-2845	178	24	of	of	ADP
fnp-2845	178	25	aβ	aβ	NOUN
fnp-2845	178	26	plaques	plaque	NOUN
fnp-2845	178	27	microglia	microglia	NOUN
fnp-2845	178	28	that	that	PRON
fnp-2845	178	29	occurred	occur	VERB
fnp-2845	178	30	in	in	ADP
fnp-2845	178	31	proximity	proximity	NOUN
fnp-2845	178	32	to	to	ADP
fnp-2845	178	33	diffuse	diffuse	VERB
fnp-2845	178	34	,	,	PUNCT
fnp-2845	178	35	fibrillar	fibrillar	ADJ
fnp-2845	178	36	,	,	PUNCT
fnp-2845	178	37	and	and	CCONJ
fnp-2845	178	38	cored	core	VERB
fnp-2845	178	39	plaques	plaque	NOUN
fnp-2845	178	40	commonly	commonly	ADV
fnp-2845	178	41	displayed	display	VERB
fnp-2845	178	42	structures	structure	NOUN
fnp-2845	178	43	morphologically	morphologically	ADV
fnp-2845	178	44	consistent	consistent	ADJ
fnp-2845	178	45	with	with	ADP
fnp-2845	178	46	phagosomes	phagosome	NOUN
fnp-2845	178	47	on	on	ADP
fnp-2845	178	48	distal	distal	ADJ
fnp-2845	178	49	processes	process	NOUN
fnp-2845	178	50	with	with	ADP
fnp-2845	178	51	enriched	enriched	ADJ
fnp-2845	178	52	iba1	iba1	NOUN
fnp-2845	178	53	immunolabelling	immunolabelle	VERB
fnp-2845	178	54	that	that	SCONJ
fnp-2845	178	55	closely	closely	ADV
fnp-2845	178	56	associated	associate	VERB
fnp-2845	178	57	with	with	ADP
fnp-2845	178	58	the	the	DET
fnp-2845	178	59	aβ	aβ	PROPN
fnp-2845	178	60	element	element	NOUN
fnp-2845	178	61	in	in	ADP
fnp-2845	178	62	the	the	DET
fnp-2845	178	63	periphery	periphery	NOUN
fnp-2845	178	64	and	and	CCONJ
fnp-2845	178	65	core	core	NOUN
fnp-2845	178	66	of	of	ADP
fnp-2845	178	67	plaques	plaque	NOUN
fnp-2845	178	68	(	(	PUNCT
fnp-2845	178	69	fig	fig	NOUN
fnp-2845	178	70	.	.	PUNCT
fnp-2845	179	1	6a	6a	NOUN
fnp-2845	179	2	;	;	PUNCT
fnp-2845	179	3	fig	fig	NOUN
fnp-2845	179	4	.	.	PUNCT
fnp-2845	180	1	7a	7a	NUM
fnp-2845	180	2	)	)	PUNCT
fnp-2845	180	3	.	.	PUNCT
fnp-2845	181	1	as	as	SCONJ
fnp-2845	181	2	previously	previously	ADV
fnp-2845	181	3	reported	report	VERB
fnp-2845	181	4	for	for	ADP
fnp-2845	181	5	the	the	DET
fnp-2845	181	6	itc	itc	PROPN
fnp-2845	181	7	,	,	PUNCT
fnp-2845	181	8	superior	superior	ADJ
fnp-2845	181	9	frontal	frontal	ADJ
fnp-2845	181	10	gyrus	gyrus	NOUN
fnp-2845	181	11	,	,	PUNCT
fnp-2845	181	12	and	and	CCONJ
fnp-2845	181	13	primary	primary	ADJ
fnp-2845	181	14	visual	visual	ADJ
fnp-2845	181	15	cortex	cortex	NOUN
fnp-2845	181	16	,	,	PUNCT
fnp-2845	181	17	the	the	DET
fnp-2845	181	18	overall	overall	ADJ
fnp-2845	181	19	density	density	NOUN
fnp-2845	181	20	of	of	ADP
fnp-2845	181	21	dystrophic	dystrophic	ADJ
fnp-2845	181	22	microglia	microglia	NOUN
fnp-2845	181	23	was	be	AUX
fnp-2845	181	24	inversely	inversely	ADV
fnp-2845	181	25	correlated	correlate	VERB
fnp-2845	181	26	with	with	ADP
fnp-2845	181	27	brain	brain	NOUN
fnp-2845	181	28	ph	ph	NOUN
fnp-2845	181	29	in	in	ADP
fnp-2845	181	30	the	the	DET
fnp-2845	181	31	pmc	pmc	PROPN
fnp-2845	181	32	(	(	PUNCT
fnp-2845	181	33	r2	r2	PROPN
fnp-2845	181	34	=	=	PUNCT
fnp-2845	181	35	0.3	0.3	NUM
fnp-2845	181	36	,	,	PUNCT
fnp-2845	181	37	p	p	X
fnp-2845	181	38	=	=	NOUN
fnp-2845	181	39	0.01	0.01	NUM
fnp-2845	181	40	)	)	PUNCT
fnp-2845	181	41	(	(	PUNCT
fnp-2845	181	42	26	26	NUM
fnp-2845	181	43	)	)	PUNCT
fnp-2845	181	44	.	.	PUNCT
fnp-2845	182	1	however	however	ADV
fnp-2845	182	2	,	,	PUNCT
fnp-2845	182	3	it	it	PRON
fnp-2845	182	4	was	be	AUX
fnp-2845	182	5	also	also	ADV
fnp-2845	182	6	noted	note	VERB
fnp-2845	182	7	that	that	SCONJ
fnp-2845	182	8	individual	individual	ADJ
fnp-2845	182	9	plaques	plaque	NOUN
fnp-2845	182	10	with	with	ADP
fnp-2845	182	11	dense	dense	ADJ
fnp-2845	182	12	dns	dns	NOUN
fnp-2845	182	13	,	,	PUNCT
fnp-2845	182	14	that	that	PRON
fnp-2845	182	15	were	be	AUX
fnp-2845	182	16	associated	associate	VERB
fnp-2845	182	17	with	with	ADP
fnp-2845	182	18	weak	weak	ADJ
fnp-2845	182	19	or	or	CCONJ
fnp-2845	182	20	absent	absent	ADJ
fnp-2845	182	21	aβ	aβ	NOUN
fnp-2845	182	22	staining	stain	VERB
fnp-2845	182	23	which	which	PRON
fnp-2845	182	24	were	be	AUX
fnp-2845	182	25	more	more	ADV
fnp-2845	182	26	abundant	abundant	ADJ
fnp-2845	182	27	in	in	ADP
fnp-2845	182	28	the	the	DET
fnp-2845	182	29	itc	itc	PROPN
fnp-2845	182	30	,	,	PUNCT
fnp-2845	182	31	were	be	AUX
fnp-2845	182	32	associated	associate	VERB
fnp-2845	182	33	with	with	ADP
fnp-2845	182	34	dystrophic	dystrophic	ADJ
fnp-2845	182	35	microglia	microglia	NOUN
fnp-2845	182	36	(	(	PUNCT
fnp-2845	182	37	fig	fig	NOUN
fnp-2845	182	38	.	.	PUNCT
fnp-2845	183	1	6b	6b	NOUN
fnp-2845	183	2	)	)	PUNCT
fnp-2845	183	3	rather	rather	ADV
fnp-2845	183	4	than	than	ADP
fnp-2845	183	5	a	a	DET
fnp-2845	183	6	cluster	cluster	NOUN
fnp-2845	183	7	of	of	ADP
fnp-2845	183	8	activated	activate	VERB
fnp-2845	183	9	microglia	microglia	NOUN
fnp-2845	183	10	which	which	PRON
fnp-2845	183	11	more	more	ADV
fnp-2845	183	12	commonly	commonly	ADV
fnp-2845	183	13	occurred	occur	VERB
fnp-2845	183	14	where	where	SCONJ
fnp-2845	183	15	the	the	DET
fnp-2845	183	16	extent	extent	NOUN
fnp-2845	183	17	of	of	ADP
fnp-2845	183	18	dns	dns	NOUN
fnp-2845	183	19	was	be	AUX
fnp-2845	183	20	not	not	PART
fnp-2845	183	21	yet	yet	ADV
fnp-2845	183	22	fully	fully	ADV
fnp-2845	183	23	developed	develop	VERB
fnp-2845	183	24	(	(	PUNCT
fnp-2845	183	25	fig	fig	NOUN
fnp-2845	183	26	.	.	PUNCT
fnp-2845	184	1	6c	6c	NOUN
fnp-2845	184	2	–	–	PUNCT
fnp-2845	184	3	d	d	NOUN
fnp-2845	184	4	)	)	PUNCT
fnp-2845	184	5	.	.	PUNCT
fnp-2845	185	1	confocal	confocal	ADJ
fnp-2845	185	2	views	view	NOUN
fnp-2845	185	3	showed	show	VERB
fnp-2845	185	4	co	co	NOUN
fnp-2845	185	5	-	-	NOUN
fnp-2845	185	6	localisation	localisation	NOUN
fnp-2845	185	7	of	of	ADP
fnp-2845	185	8	microglial	microglial	ADJ
fnp-2845	185	9	cell	cell	NOUN
fnp-2845	185	10	processes	process	NOUN
fnp-2845	185	11	with	with	ADP
fnp-2845	185	12	aβ	aβ	PRON
fnp-2845	185	13	in	in	ADP
fnp-2845	185	14	ad	ad	NOUN
fnp-2845	185	15	(	(	PUNCT
fnp-2845	185	16	fig	fig	NOUN
fnp-2845	185	17	.	.	PUNCT
fnp-2845	186	1	7a	7a	NUM
fnp-2845	186	2	–	–	PUNCT
fnp-2845	186	3	b	b	NOUN
fnp-2845	186	4	)	)	PUNCT
fnp-2845	186	5	,	,	PUNCT
fnp-2845	186	6	but	but	CCONJ
fnp-2845	186	7	no	no	DET
fnp-2845	186	8	co	co	NOUN
fnp-2845	186	9	-	-	NOUN
fnp-2845	186	10	localisation	localisation	NOUN
fnp-2845	186	11	with	with	ADP
fnp-2845	186	12	tau	tau	PROPN
fnp-2845	186	13	pathology	pathology	NOUN
fnp-2845	186	14	(	(	PUNCT
fnp-2845	186	15	fig	fig	NOUN
fnp-2845	186	16	.	.	PUNCT
fnp-2845	187	1	7c	7c	NUM
fnp-2845	187	2	–	–	PUNCT
fnp-2845	187	3	d	d	NOUN
fnp-2845	187	4	)	)	PUNCT
fnp-2845	187	5	.	.	PUNCT
fnp-2845	188	1	figure	figure	VERB
fnp-2845	188	2	6	6	NUM
fnp-2845	188	3	responses	response	NOUN
fnp-2845	188	4	of	of	ADP
fnp-2845	188	5	microglia	microglia	NOUN
fnp-2845	188	6	to	to	ADP
fnp-2845	188	7	ad	ad	NOUN
fnp-2845	188	8	neuropathology	neuropathology	NOUN
fnp-2845	188	9	.	.	PUNCT
fnp-2845	189	1	a	a	DET
fnp-2845	189	2	the	the	DET
fnp-2845	189	3	itc	itc	NOUN
fnp-2845	189	4	of	of	ADP
fnp-2845	189	5	a	a	DET
fnp-2845	189	6	control	control	NOUN
fnp-2845	189	7	case	case	NOUN
fnp-2845	189	8	(	(	PUNCT
fnp-2845	189	9	m01	m01	NUM
fnp-2845	189	10	)	)	PUNCT
fnp-2845	189	11	demonstrating	demonstrating	NOUN
fnp-2845	189	12	activated	activate	VERB
fnp-2845	189	13	microglia	microglia	NOUN
fnp-2845	189	14	with	with	ADP
fnp-2845	189	15	morphological	morphological	ADJ
fnp-2845	189	16	features	feature	NOUN
fnp-2845	189	17	consistent	consistent	ADJ
fnp-2845	189	18	with	with	ADP
fnp-2845	189	19	the	the	DET
fnp-2845	189	20	formation	formation	NOUN
fnp-2845	189	21	of	of	ADP
fnp-2845	189	22	phagosomes	phagosome	NOUN
fnp-2845	189	23	(	(	PUNCT
fnp-2845	189	24	arrows	arrow	NOUN
fnp-2845	189	25	)	)	PUNCT
fnp-2845	189	26	responding	respond	VERB
fnp-2845	189	27	to	to	ADP
fnp-2845	189	28	peripheral	peripheral	ADJ
fnp-2845	189	29	and	and	CCONJ
fnp-2845	189	30	core	core	NOUN
fnp-2845	189	31	elements	element	NOUN
fnp-2845	189	32	of	of	ADP
fnp-2845	189	33	an	an	DET
fnp-2845	189	34	aβ	aβ	NOUN
fnp-2845	189	35	plaque	plaque	NOUN
fnp-2845	189	36	.	.	PUNCT
fnp-2845	190	1	b	b	NOUN
fnp-2845	190	2	in	in	ADP
fnp-2845	190	3	the	the	DET
fnp-2845	190	4	itc	itc	NOUN
fnp-2845	190	5	of	of	ADP
fnp-2845	190	6	ad	ad	NOUN
fnp-2845	190	7	cases	case	NOUN
fnp-2845	190	8	(	(	PUNCT
fnp-2845	190	9	m17	m17	PROPN
fnp-2845	190	10	pictured	picture	VERB
fnp-2845	190	11	)	)	PUNCT
fnp-2845	190	12	,	,	PUNCT
fnp-2845	190	13	dystrophic	dystrophic	ADJ
fnp-2845	190	14	microglia	microglia	NOUN
fnp-2845	190	15	were	be	AUX
fnp-2845	190	16	more	more	ADV
fnp-2845	190	17	commonly	commonly	ADV
fnp-2845	190	18	associated	associate	VERB
fnp-2845	190	19	with	with	ADP
fnp-2845	190	20	plaques	plaque	NOUN
fnp-2845	190	21	that	that	PRON
fnp-2845	190	22	contained	contain	VERB
fnp-2845	190	23	dense	dense	ADJ
fnp-2845	190	24	accumulations	accumulation	NOUN
fnp-2845	190	25	of	of	ADP
fnp-2845	190	26	dystrophic	dystrophic	ADJ
fnp-2845	190	27	neurites	neurite	NOUN
fnp-2845	190	28	,	,	PUNCT
fnp-2845	190	29	however	however	ADV
fnp-2845	190	30	the	the	DET
fnp-2845	190	31	overall	overall	ADJ
fnp-2845	190	32	density	density	NOUN
fnp-2845	190	33	of	of	ADP
fnp-2845	190	34	dystrophic	dystrophic	ADJ
fnp-2845	190	35	microglia	microglia	NOUN
fnp-2845	190	36	was	be	AUX
fnp-2845	190	37	inversely	inversely	ADV
fnp-2845	190	38	correlated	correlate	VERB
fnp-2845	190	39	with	with	ADP
fnp-2845	190	40	brain	brain	NOUN
fnp-2845	190	41	ph	ph	NOUN
fnp-2845	190	42	and	and	CCONJ
fnp-2845	190	43	not	not	PART
fnp-2845	190	44	with	with	ADP
fnp-2845	190	45	ad	ad	NOUN
fnp-2845	190	46	.	.	PUNCT
fnp-2845	191	1	c	c	X
fnp-2845	191	2	–	–	PUNCT
fnp-2845	191	3	d	d	NOUN
fnp-2845	191	4	conversely	conversely	ADV
fnp-2845	191	5	,	,	PUNCT
fnp-2845	191	6	plaques	plaque	NOUN
fnp-2845	191	7	with	with	ADP
fnp-2845	191	8	a	a	DET
fnp-2845	191	9	lower	low	ADJ
fnp-2845	191	10	density	density	NOUN
fnp-2845	191	11	of	of	ADP
fnp-2845	191	12	dystrophic	dystrophic	ADJ
fnp-2845	191	13	neurites	neurite	NOUN
fnp-2845	191	14	were	be	AUX
fnp-2845	191	15	more	more	ADV
fnp-2845	191	16	commonly	commonly	ADV
fnp-2845	191	17	associated	associate	VERB
fnp-2845	191	18	with	with	ADP
fnp-2845	191	19	a	a	DET
fnp-2845	191	20	cluster	cluster	NOUN
fnp-2845	191	21	of	of	ADP
fnp-2845	191	22	activated	activate	VERB
fnp-2845	191	23	microglia	microglia	NOUN
fnp-2845	191	24	(	(	PUNCT
fnp-2845	191	25	m01	m01	PROPN
fnp-2845	191	26	pictured	picture	VERB
fnp-2845	191	27	)	)	PUNCT
fnp-2845	191	28	in	in	ADP
fnp-2845	191	29	both	both	CCONJ
fnp-2845	191	30	the	the	DET
fnp-2845	191	31	pmc	pmc	PROPN
fnp-2845	191	32	(	(	PUNCT
fnp-2845	191	33	c	c	NOUN
fnp-2845	191	34	)	)	PUNCT
fnp-2845	191	35	and	and	CCONJ
fnp-2845	191	36	itc	itc	PROPN
fnp-2845	191	37	(	(	PUNCT
fnp-2845	191	38	d	d	NOUN
fnp-2845	191	39	)	)	PUNCT
fnp-2845	191	40	.	.	PUNCT
fnp-2845	192	1	scale	scale	NOUN
fnp-2845	192	2	bar	bar	NOUN
fnp-2845	192	3	=	=	PUNCT
fnp-2845	192	4	20	20	NUM
fnp-2845	192	5	μm	μm	NOUN
fnp-2845	192	6	(	(	PUNCT
fnp-2845	192	7	a	a	DET
fnp-2845	192	8	–	–	PUNCT
fnp-2845	192	9	d	d	NOUN
fnp-2845	192	10	)	)	PUNCT
fnp-2845	192	11	figure	figure	NOUN
fnp-2845	192	12	7	7	NUM
fnp-2845	192	13	exemplars	exemplar	NOUN
fnp-2845	192	14	from	from	ADP
fnp-2845	192	15	an	an	DET
fnp-2845	192	16	investigation	investigation	NOUN
fnp-2845	192	17	into	into	ADP
fnp-2845	192	18	the	the	DET
fnp-2845	192	19	potential	potential	ADJ
fnp-2845	192	20	internalisation	internalisation	NOUN
fnp-2845	192	21	of	of	ADP
fnp-2845	192	22	aβ	aβ	PRON
fnp-2845	192	23	and	and	CCONJ
fnp-2845	192	24	tau	tau	PROPN
fnp-2845	192	25	pathology	pathology	NOUN
fnp-2845	192	26	by	by	ADP
fnp-2845	192	27	microglia	microglia	PROPN
fnp-2845	192	28	.	.	PUNCT
fnp-2845	193	1	a	a	DET
fnp-2845	193	2	activated	activate	VERB
fnp-2845	193	3	microglia	microglia	NOUN
fnp-2845	193	4	in	in	ADP
fnp-2845	193	5	an	an	DET
fnp-2845	193	6	aβ	aβ	NOUN
fnp-2845	193	7	plaque	plaque	NOUN
fnp-2845	193	8	in	in	ADP
fnp-2845	193	9	the	the	DET
fnp-2845	193	10	itc	itc	NOUN
fnp-2845	193	11	of	of	ADP
fnp-2845	193	12	a	a	DET
fnp-2845	193	13	control	control	NOUN
fnp-2845	193	14	case	case	NOUN
fnp-2845	193	15	with	with	ADP
fnp-2845	193	16	morphological	morphological	ADJ
fnp-2845	193	17	features	feature	NOUN
fnp-2845	193	18	consistent	consistent	ADJ
fnp-2845	193	19	with	with	ADP
fnp-2845	193	20	the	the	DET
fnp-2845	193	21	formation	formation	NOUN
fnp-2845	193	22	of	of	ADP
fnp-2845	193	23	phagosomes	phagosome	NOUN
fnp-2845	193	24	(	(	PUNCT
fnp-2845	193	25	arrows	arrow	NOUN
fnp-2845	193	26	)	)	PUNCT
fnp-2845	193	27	(	(	PUNCT
fnp-2845	193	28	m01	m01	NUM
fnp-2845	193	29	;	;	PUNCT
fnp-2845	193	30	dotted	dotted	PROPN
fnp-2845	193	31	box	box	PROPN
fnp-2845	193	32	represents	represent	VERB
fnp-2845	193	33	region	region	NOUN
fnp-2845	193	34	of	of	ADP
fnp-2845	193	35	interest	interest	NOUN
fnp-2845	193	36	in	in	ADP
fnp-2845	193	37	b	b	NOUN
fnp-2845	193	38	)	)	PUNCT
fnp-2845	193	39	.	.	PUNCT
fnp-2845	194	1	b	b	X
fnp-2845	194	2	coincidence	coincidence	NOUN
fnp-2845	194	3	of	of	ADP
fnp-2845	194	4	aβ	aβ	NOUN
fnp-2845	194	5	and	and	CCONJ
fnp-2845	194	6	iba1	iba1	PROPN
fnp-2845	194	7	pixel	pixel	PROPN
fnp-2845	194	8	intensities	intensity	NOUN
fnp-2845	194	9	along	along	ADP
fnp-2845	194	10	a	a	DET
fnp-2845	194	11	7.8	7.8	NUM
fnp-2845	194	12	μm	μm	NOUN
fnp-2845	194	13	length	length	NOUN
fnp-2845	194	14	(	(	PUNCT
fnp-2845	194	15	dotted	dotted	ADJ
fnp-2845	194	16	line	line	NOUN
fnp-2845	194	17	)	)	PUNCT
fnp-2845	194	18	suggests	suggest	VERB
fnp-2845	194	19	potential	potential	ADJ
fnp-2845	194	20	internalisation	internalisation	NOUN
fnp-2845	194	21	of	of	ADP
fnp-2845	194	22	aβ	aβ	NOUN
fnp-2845	194	23	by	by	ADP
fnp-2845	194	24	microglia	microglia	NOUN
fnp-2845	194	25	.	.	PUNCT
fnp-2845	195	1	c	c	PROPN
fnp-2845	195	2	activated	activate	VERB
fnp-2845	195	3	microglia	microglia	NOUN
fnp-2845	195	4	in	in	ADP
fnp-2845	195	5	close	close	ADJ
fnp-2845	195	6	proximity	proximity	NOUN
fnp-2845	195	7	to	to	ADP
fnp-2845	195	8	tau	tau	NOUN
fnp-2845	195	9	-	-	PUNCT
fnp-2845	195	10	positive	positive	ADJ
fnp-2845	195	11	dns	dns	NOUN
fnp-2845	195	12	in	in	ADP
fnp-2845	195	13	the	the	DET
fnp-2845	195	14	itc	itc	NOUN
fnp-2845	195	15	of	of	ADP
fnp-2845	195	16	an	an	DET
fnp-2845	195	17	ad	ad	NOUN
fnp-2845	195	18	case	case	NOUN
fnp-2845	195	19	(	(	PUNCT
fnp-2845	195	20	m17	m17	NUM
fnp-2845	195	21	;	;	PUNCT
fnp-2845	195	22	dotted	dotted	PROPN
fnp-2845	195	23	box	box	PROPN
fnp-2845	195	24	represents	represent	VERB
fnp-2845	195	25	region	region	NOUN
fnp-2845	195	26	of	of	ADP
fnp-2845	195	27	interest	interest	NOUN
fnp-2845	195	28	in	in	ADP
fnp-2845	195	29	d	d	NOUN
fnp-2845	195	30	)	)	PUNCT
fnp-2845	195	31	.	.	PUNCT
fnp-2845	196	1	d	d	X
fnp-2845	196	2	there	there	PRON
fnp-2845	196	3	was	be	VERB
fnp-2845	196	4	no	no	DET
fnp-2845	196	5	evidence	evidence	NOUN
fnp-2845	196	6	of	of	ADP
fnp-2845	196	7	the	the	DET
fnp-2845	196	8	internalisation	internalisation	NOUN
fnp-2845	196	9	of	of	ADP
fnp-2845	196	10	tau	tau	PROPN
fnp-2845	196	11	pathology	pathology	NOUN
fnp-2845	196	12	by	by	ADP
fnp-2845	196	13	microglia	microglia	NOUN
fnp-2845	196	14	in	in	ADP
fnp-2845	196	15	any	any	PRON
fnp-2845	196	16	of	of	ADP
fnp-2845	196	17	the	the	DET
fnp-2845	196	18	sections	section	NOUN
fnp-2845	196	19	investigated	investigate	VERB
fnp-2845	196	20	here	here	ADV
fnp-2845	196	21	;	;	PUNCT
fnp-2845	196	22	exemplar	exemplar	NOUN
fnp-2845	196	23	shows	show	VERB
fnp-2845	196	24	aβ	aβ	VERB
fnp-2845	196	25	and	and	CCONJ
fnp-2845	196	26	ttau	ttau	AUX
fnp-2845	196	27	staining	stain	VERB
fnp-2845	196	28	intensities	intensity	NOUN
fnp-2845	196	29	over	over	ADP
fnp-2845	196	30	a	a	DET
fnp-2845	196	31	7.2	7.2	NUM
fnp-2845	196	32	μm	μm	NOUN
fnp-2845	196	33	length	length	NOUN
fnp-2845	196	34	(	(	PUNCT
fnp-2845	196	35	dotted	dotted	ADJ
fnp-2845	196	36	line	line	NOUN
fnp-2845	196	37	)	)	PUNCT
fnp-2845	196	38	.	.	PUNCT
fnp-2845	197	1	scale	scale	NOUN
fnp-2845	197	2	bar	bar	NOUN
fnp-2845	197	3	20	20	NUM
fnp-2845	197	4	μm	μm	NOUN
fnp-2845	197	5	(	(	PUNCT
fnp-2845	197	6	a	a	PRON
fnp-2845	197	7	,	,	PUNCT
fnp-2845	197	8	c	c	NOUN
fnp-2845	197	9	)	)	PUNCT
fnp-2845	197	10	discussion	discussion	NOUN
fnp-2845	197	11	ad	ad	NOUN
fnp-2845	197	12	is	be	AUX
fnp-2845	197	13	a	a	DET
fnp-2845	197	14	uniquely	uniquely	ADV
fnp-2845	197	15	human	human	ADJ
fnp-2845	197	16	disease	disease	NOUN
fnp-2845	197	17	with	with	ADP
fnp-2845	197	18	a	a	DET
fnp-2845	197	19	long	long	ADJ
fnp-2845	197	20	prodrome	prodrome	NOUN
fnp-2845	197	21	and	and	CCONJ
fnp-2845	197	22	has	have	AUX
fnp-2845	197	23	proved	prove	VERB
fnp-2845	197	24	difficult	difficult	ADJ
fnp-2845	197	25	to	to	PART
fnp-2845	197	26	model	model	VERB
fnp-2845	197	27	.	.	PUNCT
fnp-2845	198	1	the	the	DET
fnp-2845	198	2	combination	combination	NOUN
fnp-2845	198	3	of	of	ADP
fnp-2845	198	4	using	use	VERB
fnp-2845	198	5	different	different	ADJ
fnp-2845	198	6	regions	region	NOUN
fnp-2845	198	7	of	of	ADP
fnp-2845	198	8	post	post	ADJ
fnp-2845	198	9	-	-	ADJ
fnp-2845	198	10	mortem	mortem	ADJ
fnp-2845	198	11	brain	brain	NOUN
fnp-2845	198	12	tissue	tissue	NOUN
fnp-2845	198	13	from	from	ADP
fnp-2845	198	14	individuals	individual	NOUN
fnp-2845	198	15	with	with	ADP
fnp-2845	198	16	or	or	CCONJ
fnp-2845	198	17	without	without	ADP
fnp-2845	198	18	dementia	dementia	NOUN
fnp-2845	198	19	and	and	CCONJ
fnp-2845	198	20	with	with	ADP
fnp-2845	198	21	variable	variable	ADJ
fnp-2845	198	22	amounts	amount	NOUN
fnp-2845	198	23	of	of	ADP
fnp-2845	198	24	ad	ad	NOUN
fnp-2845	198	25	-	-	PUNCT
fnp-2845	198	26	type	type	NOUN
fnp-2845	198	27	pathology	pathology	NOUN
fnp-2845	198	28	may	may	AUX
fnp-2845	198	29	allow	allow	VERB
fnp-2845	198	30	the	the	DET
fnp-2845	198	31	pathological	pathological	ADJ
fnp-2845	198	32	sequence	sequence	NOUN
fnp-2845	198	33	of	of	ADP
fnp-2845	198	34	events	event	NOUN
fnp-2845	198	35	to	to	PART
fnp-2845	198	36	be	be	AUX
fnp-2845	198	37	elucidated	elucidate	VERB
fnp-2845	198	38	.	.	PUNCT
fnp-2845	199	1	for	for	ADP
fnp-2845	199	2	example	example	NOUN
fnp-2845	199	3	,	,	PUNCT
fnp-2845	199	4	the	the	DET
fnp-2845	199	5	level	level	NOUN
fnp-2845	199	6	of	of	ADP
fnp-2845	199	7	disease	disease	NOUN
fnp-2845	199	8	severity	severity	NOUN
fnp-2845	199	9	could	could	AUX
fnp-2845	199	10	be	be	AUX
fnp-2845	199	11	ordered	order	VERB
fnp-2845	199	12	from	from	ADP
fnp-2845	199	13	lowest	low	ADJ
fnp-2845	199	14	to	to	ADP
fnp-2845	199	15	highest	high	ADJ
fnp-2845	199	16	as	as	SCONJ
fnp-2845	199	17	follows	follow	VERB
fnp-2845	199	18	:	:	PUNCT
fnp-2845	199	19	pmc	pmc	NOUN
fnp-2845	199	20	-	-	PUNCT
fnp-2845	199	21	controls	control	VERB
fnp-2845	199	22	<	<	X
fnp-2845	199	23	itc	itc	PROPN
fnp-2845	199	24	-	-	PUNCT
fnp-2845	199	25	controls	control	NOUN
fnp-2845	199	26	<	<	X
fnp-2845	199	27	pmc	pmc	PROPN
fnp-2845	199	28	-	-	PROPN
fnp-2845	199	29	hpc	hpc	PROPN
fnp-2845	199	30	<	<	X
fnp-2845	199	31	itc	itc	PROPN
fnp-2845	199	32	-	-	PUNCT
fnp-2845	199	33	hpc	hpc	PROPN
fnp-2845	199	34	<	<	X
fnp-2845	199	35	pmc	pmc	PROPN
fnp-2845	199	36	-	-	PUNCT
fnp-2845	199	37	ad	ad	NOUN
fnp-2845	199	38	<	<	X
fnp-2845	199	39	itc	itc	PROPN
fnp-2845	199	40	-	-	PUNCT
fnp-2845	199	41	ad	ad	NOUN
fnp-2845	199	42	.	.	PUNCT
fnp-2845	200	1	in	in	ADP
fnp-2845	200	2	particular	particular	ADJ
fnp-2845	200	3	,	,	PUNCT
fnp-2845	200	4	regions	region	NOUN
fnp-2845	200	5	such	such	ADJ
fnp-2845	200	6	as	as	ADP
fnp-2845	200	7	the	the	DET
fnp-2845	200	8	itc	itc	PROPN
fnp-2845	200	9	in	in	ADP
fnp-2845	200	10	hpcs	hpc	NOUN
fnp-2845	200	11	and	and	CCONJ
fnp-2845	200	12	the	the	DET
fnp-2845	200	13	pmc	pmc	PROPN
fnp-2845	200	14	in	in	ADP
fnp-2845	200	15	ad	ad	NOUN
fnp-2845	200	16	cases	case	NOUN
fnp-2845	200	17	could	could	AUX
fnp-2845	200	18	harbour	harbour	VERB
fnp-2845	200	19	the	the	DET
fnp-2845	200	20	pre	pre	ADJ
fnp-2845	200	21	-	-	ADJ
fnp-2845	200	22	symptomatic	symptomatic	ADJ
fnp-2845	200	23	targets	target	NOUN
fnp-2845	200	24	required	require	VERB
fnp-2845	200	25	to	to	PART
fnp-2845	200	26	therapeutically	therapeutically	ADV
fnp-2845	200	27	delay	delay	VERB
fnp-2845	200	28	or	or	CCONJ
fnp-2845	200	29	prevent	prevent	VERB
fnp-2845	200	30	ad	ad	NOUN
fnp-2845	200	31	.	.	PUNCT
fnp-2845	201	1	prior	prior	ADV
fnp-2845	201	2	to	to	ADP
fnp-2845	201	3	using	use	VERB
fnp-2845	201	4	this	this	DET
fnp-2845	201	5	model	model	NOUN
fnp-2845	201	6	to	to	PART
fnp-2845	201	7	understand	understand	VERB
fnp-2845	201	8	the	the	DET
fnp-2845	201	9	role	role	NOUN
fnp-2845	201	10	of	of	ADP
fnp-2845	201	11	microglia	microglia	NOUN
fnp-2845	201	12	in	in	ADP
fnp-2845	201	13	ad	ad	NOUN
fnp-2845	201	14	,	,	PUNCT
fnp-2845	201	15	a	a	DET
fnp-2845	201	16	quantitative	quantitative	ADJ
fnp-2845	201	17	neuropathological	neuropathological	ADJ
fnp-2845	201	18	analysis	analysis	NOUN
fnp-2845	201	19	of	of	ADP
fnp-2845	201	20	the	the	DET
fnp-2845	201	21	pmc	pmc	PROPN
fnp-2845	201	22	was	be	AUX
fnp-2845	201	23	carried	carry	VERB
fnp-2845	201	24	out	out	ADP
fnp-2845	201	25	to	to	PART
fnp-2845	201	26	ensure	ensure	VERB
fnp-2845	201	27	that	that	SCONJ
fnp-2845	201	28	it	it	PRON
fnp-2845	201	29	met	meet	VERB
fnp-2845	201	30	expectations	expectation	NOUN
fnp-2845	201	31	for	for	ADP
fnp-2845	201	32	being	be	AUX
fnp-2845	201	33	a	a	DET
fnp-2845	201	34	relatively	relatively	ADV
fnp-2845	201	35	unaffected	unaffected	ADJ
fnp-2845	201	36	region	region	NOUN
fnp-2845	201	37	of	of	ADP
fnp-2845	201	38	the	the	DET
fnp-2845	201	39	ad	ad	NOUN
fnp-2845	201	40	brain	brain	NOUN
fnp-2845	201	41	.	.	PUNCT
fnp-2845	202	1	as	as	SCONJ
fnp-2845	202	2	expected	expect	VERB
fnp-2845	202	3	,	,	PUNCT
fnp-2845	202	4	the	the	DET
fnp-2845	202	5	pmc	pmc	PROPN
fnp-2845	202	6	of	of	ADP
fnp-2845	202	7	ad	ad	NOUN
fnp-2845	202	8	cases	case	NOUN
fnp-2845	202	9	had	have	VERB
fnp-2845	202	10	a	a	DET
fnp-2845	202	11	significantly	significantly	ADV
fnp-2845	202	12	higher	high	ADJ
fnp-2845	202	13	%	%	NOUN
fnp-2845	202	14	aβ	aβ	INTJ
fnp-2845	202	15	,	,	PUNCT
fnp-2845	202	16	aβ	aβ	PRON
fnp-2845	202	17	plaque	plaque	NOUN
fnp-2845	202	18	count	count	NOUN
fnp-2845	202	19	,	,	PUNCT
fnp-2845	202	20	%	%	NOUN
fnp-2845	202	21	ttau	ttau	VERB
fnp-2845	202	22	,	,	PUNCT
fnp-2845	202	23	and	and	CCONJ
fnp-2845	202	24	nft	nft	PROPN
fnp-2845	202	25	density	density	NOUN
fnp-2845	202	26	compared	compare	VERB
fnp-2845	202	27	controls	control	NOUN
fnp-2845	202	28	.	.	PUNCT
fnp-2845	203	1	there	there	PRON
fnp-2845	203	2	were	be	VERB
fnp-2845	203	3	no	no	DET
fnp-2845	203	4	nfts	nft	NOUN
fnp-2845	203	5	observed	observe	VERB
fnp-2845	203	6	in	in	ADP
fnp-2845	203	7	the	the	DET
fnp-2845	203	8	pmc	pmc	PROPN
fnp-2845	203	9	of	of	ADP
fnp-2845	203	10	controls	control	NOUN
fnp-2845	203	11	and	and	CCONJ
fnp-2845	203	12	hpcs	hpc	NOUN
fnp-2845	203	13	,	,	PUNCT
fnp-2845	203	14	which	which	PRON
fnp-2845	203	15	also	also	ADV
fnp-2845	203	16	had	have	VERB
fnp-2845	203	17	very	very	ADV
fnp-2845	203	18	similar	similar	ADJ
fnp-2845	203	19	levels	level	NOUN
fnp-2845	203	20	of	of	ADP
fnp-2845	203	21	%	%	NOUN
fnp-2845	203	22	ttau	ttau	PROPN
fnp-2845	203	23	(	(	PUNCT
fnp-2845	203	24	which	which	PRON
fnp-2845	203	25	correlated	correlate	VERB
fnp-2845	203	26	with	with	ADP
fnp-2845	203	27	increasing	increase	VERB
fnp-2845	203	28	age	age	NOUN
fnp-2845	203	29	)	)	PUNCT
fnp-2845	203	30	,	,	PUNCT
fnp-2845	203	31	but	but	CCONJ
fnp-2845	203	32	differed	differ	VERB
fnp-2845	203	33	in	in	ADP
fnp-2845	203	34	their	their	PRON
fnp-2845	203	35	level	level	NOUN
fnp-2845	203	36	of	of	ADP
fnp-2845	203	37	%	%	NOUN
fnp-2845	203	38	aβ	aβ	PROPN
fnp-2845	203	39	.	.	PUNCT
fnp-2845	203	40	hpcs	hpc	NOUN
fnp-2845	203	41	were	be	AUX
fnp-2845	203	42	defined	define	VERB
fnp-2845	203	43	according	accord	VERB
fnp-2845	203	44	to	to	ADP
fnp-2845	203	45	standard	standard	ADJ
fnp-2845	203	46	neuropathological	neuropathological	ADJ
fnp-2845	203	47	diagnostic	diagnostic	ADJ
fnp-2845	203	48	criteria	criterion	NOUN
fnp-2845	203	49	–	–	PUNCT
fnp-2845	203	50	having	have	VERB
fnp-2845	203	51	an	an	DET
fnp-2845	203	52	intermediate	intermediate	ADJ
fnp-2845	203	53	abc	abc	PROPN
fnp-2845	203	54	score	score	NOUN
fnp-2845	203	55	(	(	PUNCT
fnp-2845	203	56	38	38	NUM
fnp-2845	203	57	)	)	PUNCT
fnp-2845	203	58	.	.	PUNCT
fnp-2845	204	1	incidentally	incidentally	ADV
fnp-2845	204	2	,	,	PUNCT
fnp-2845	204	3	hpcs	hpc	NOUN
fnp-2845	204	4	and	and	CCONJ
fnp-2845	204	5	ad	ad	NOUN
fnp-2845	204	6	cases	case	NOUN
fnp-2845	204	7	(	(	PUNCT
fnp-2845	204	8	intermediate	intermediate	ADJ
fnp-2845	204	9	–	–	PUNCT
fnp-2845	204	10	high	high	ADJ
fnp-2845	204	11	abc	abc	PROPN
fnp-2845	204	12	scores	score	NOUN
fnp-2845	204	13	)	)	PUNCT
fnp-2845	204	14	were	be	AUX
fnp-2845	204	15	similar	similar	ADJ
fnp-2845	204	16	in	in	ADP
fnp-2845	204	17	their	their	PRON
fnp-2845	204	18	aβ	aβ	NOUN
fnp-2845	204	19	load	load	NOUN
fnp-2845	204	20	but	but	CCONJ
fnp-2845	204	21	differed	differ	VERB
fnp-2845	204	22	in	in	ADP
fnp-2845	204	23	their	their	PRON
fnp-2845	204	24	tau	tau	PROPN
fnp-2845	204	25	levels	level	NOUN
fnp-2845	204	26	in	in	ADP
fnp-2845	204	27	both	both	DET
fnp-2845	204	28	regions	region	NOUN
fnp-2845	204	29	.	.	PUNCT
fnp-2845	205	1	in	in	ADP
fnp-2845	205	2	contrast	contrast	NOUN
fnp-2845	205	3	to	to	ADP
fnp-2845	205	4	the	the	DET
fnp-2845	205	5	primary	primary	ADJ
fnp-2845	205	6	visual	visual	ADJ
fnp-2845	205	7	cortex	cortex	NOUN
fnp-2845	205	8	previously	previously	ADV
fnp-2845	205	9	investigated	investigate	VERB
fnp-2845	205	10	(	(	PUNCT
fnp-2845	205	11	26	26	NUM
fnp-2845	205	12	)	)	PUNCT
fnp-2845	205	13	,	,	PUNCT
fnp-2845	205	14	the	the	DET
fnp-2845	205	15	pmc	pmc	PROPN
fnp-2845	205	16	in	in	ADP
fnp-2845	205	17	ad	ad	NOUN
fnp-2845	205	18	did	do	AUX
fnp-2845	205	19	have	have	VERB
fnp-2845	205	20	significantly	significantly	ADV
fnp-2845	205	21	reduced	reduce	VERB
fnp-2845	205	22	levels	level	NOUN
fnp-2845	205	23	of	of	ADP
fnp-2845	205	24	aβ	aβ	NOUN
fnp-2845	205	25	and	and	CCONJ
fnp-2845	205	26	overall	overall	ADJ
fnp-2845	205	27	tau	tau	PROPN
fnp-2845	205	28	pathology	pathology	NOUN
fnp-2845	205	29	,	,	PUNCT
fnp-2845	205	30	including	include	VERB
fnp-2845	205	31	nfts	nft	NOUN
fnp-2845	205	32	as	as	ADV
fnp-2845	205	33	well	well	ADV
fnp-2845	205	34	evidenced	evidence	VERB
fnp-2845	205	35	elsewhere	elsewhere	ADV
fnp-2845	205	36	(	(	PUNCT
fnp-2845	205	37	41	41	NUM
fnp-2845	205	38	-	-	SYM
fnp-2845	205	39	46	46	NUM
fnp-2845	205	40	)	)	PUNCT
fnp-2845	205	41	,	,	PUNCT
fnp-2845	205	42	compared	compare	VERB
fnp-2845	205	43	to	to	ADP
fnp-2845	205	44	the	the	DET
fnp-2845	205	45	itc	itc	NOUN
fnp-2845	205	46	of	of	ADP
fnp-2845	205	47	the	the	DET
fnp-2845	205	48	same	same	ADJ
fnp-2845	205	49	cases	case	NOUN
fnp-2845	205	50	.	.	PUNCT
fnp-2845	206	1	overall	overall	ADV
fnp-2845	206	2	there	there	PRON
fnp-2845	206	3	was	be	VERB
fnp-2845	206	4	no	no	DET
fnp-2845	206	5	evidence	evidence	NOUN
fnp-2845	206	6	of	of	ADP
fnp-2845	206	7	neurodegeneration	neurodegeneration	NOUN
fnp-2845	206	8	in	in	ADP
fnp-2845	206	9	the	the	DET
fnp-2845	206	10	pmc	pmc	PROPN
fnp-2845	206	11	of	of	ADP
fnp-2845	206	12	ad	ad	NOUN
fnp-2845	206	13	cases	case	NOUN
fnp-2845	206	14	,	,	PUNCT
fnp-2845	206	15	unlike	unlike	ADP
fnp-2845	206	16	the	the	DET
fnp-2845	206	17	itc	itc	PROPN
fnp-2845	206	18	,	,	PUNCT
fnp-2845	206	19	with	with	ADP
fnp-2845	206	20	cortical	cortical	ADJ
fnp-2845	206	21	thickness	thickness	NOUN
fnp-2845	206	22	,	,	PUNCT
fnp-2845	206	23	number	number	NOUN
fnp-2845	206	24	of	of	ADP
fnp-2845	206	25	total	total	ADJ
fnp-2845	206	26	neurons	neuron	NOUN
fnp-2845	206	27	,	,	PUNCT
fnp-2845	206	28	and	and	CCONJ
fnp-2845	206	29	giant	giant	ADJ
fnp-2845	206	30	layer	layer	NOUN
fnp-2845	206	31	vb	vb	NOUN
fnp-2845	206	32	pyramidal	pyramidal	NOUN
fnp-2845	206	33	betz	betz	NOUN
fnp-2845	206	34	cells	cell	NOUN
fnp-2845	206	35	remaining	remain	VERB
fnp-2845	206	36	unchanged	unchanged	ADJ
fnp-2845	206	37	as	as	SCONJ
fnp-2845	206	38	expected	expect	VERB
fnp-2845	206	39	(	(	PUNCT
fnp-2845	206	40	47	47	NUM
fnp-2845	206	41	,	,	PUNCT
fnp-2845	206	42	48	48	NUM
fnp-2845	206	43	)	)	PUNCT
fnp-2845	206	44	.	.	PUNCT
fnp-2845	207	1	examination	examination	NOUN
fnp-2845	207	2	of	of	ADP
fnp-2845	207	3	the	the	DET
fnp-2845	207	4	microglial	microglial	ADJ
fnp-2845	207	5	morphologies	morphology	NOUN
fnp-2845	207	6	in	in	ADP
fnp-2845	207	7	the	the	DET
fnp-2845	207	8	pmc	pmc	NOUN
fnp-2845	207	9	using	use	VERB
fnp-2845	207	10	the	the	DET
fnp-2845	207	11	previously	previously	ADV
fnp-2845	207	12	validated	validate	VERB
fnp-2845	207	13	modified	modify	VERB
fnp-2845	207	14	disector	disector	NOUN
fnp-2845	207	15	sampling	sample	VERB
fnp-2845	207	16	approach	approach	NOUN
fnp-2845	207	17	across	across	ADP
fnp-2845	207	18	all	all	DET
fnp-2845	207	19	cortical	cortical	ADJ
fnp-2845	207	20	laminae	laminae	NOUN
fnp-2845	207	21	yielded	yield	VERB
fnp-2845	207	22	no	no	DET
fnp-2845	207	23	significant	significant	ADJ
fnp-2845	207	24	differences	difference	NOUN
fnp-2845	207	25	between	between	ADP
fnp-2845	207	26	controls	control	NOUN
fnp-2845	207	27	,	,	PUNCT
fnp-2845	207	28	hpcs	hpc	NOUN
fnp-2845	207	29	,	,	PUNCT
fnp-2845	207	30	and	and	CCONJ
fnp-2845	207	31	ad	ad	NOUN
fnp-2845	207	32	cases	case	NOUN
fnp-2845	207	33	.	.	PUNCT
fnp-2845	208	1	however	however	ADV
fnp-2845	208	2	,	,	PUNCT
fnp-2845	208	3	group	group	NOUN
fnp-2845	208	4	differences	difference	NOUN
fnp-2845	208	5	could	could	AUX
fnp-2845	208	6	be	be	AUX
fnp-2845	208	7	seen	see	VERB
fnp-2845	208	8	locally	locally	ADV
fnp-2845	208	9	around	around	ADP
fnp-2845	208	10	ad	ad	NOUN
fnp-2845	208	11	-	-	PUNCT
fnp-2845	208	12	type	type	NOUN
fnp-2845	208	13	pathology	pathology	NOUN
fnp-2845	208	14	within	within	ADP
fnp-2845	208	15	the	the	DET
fnp-2845	208	16	cortex	cortex	NOUN
fnp-2845	208	17	with	with	ADP
fnp-2845	208	18	an	an	DET
fnp-2845	208	19	increase	increase	NOUN
fnp-2845	208	20	in	in	ADP
fnp-2845	208	21	clustering	clustering	NOUN
fnp-2845	208	22	of	of	ADP
fnp-2845	208	23	activated	activated	ADJ
fnp-2845	208	24	microglia	microglia	NOUN
fnp-2845	208	25	in	in	ADP
fnp-2845	208	26	the	the	DET
fnp-2845	208	27	pmc	pmc	PROPN
fnp-2845	208	28	of	of	ADP
fnp-2845	208	29	hpcs	hpc	NOUN
fnp-2845	208	30	compared	compare	VERB
fnp-2845	208	31	to	to	ADP
fnp-2845	208	32	controls	control	NOUN
fnp-2845	208	33	,	,	PUNCT
fnp-2845	208	34	and	and	CCONJ
fnp-2845	208	35	in	in	ADP
fnp-2845	208	36	the	the	DET
fnp-2845	208	37	pmc	pmc	NOUN
fnp-2845	208	38	compared	compare	VERB
fnp-2845	208	39	to	to	ADP
fnp-2845	208	40	the	the	DET
fnp-2845	208	41	itc	itc	NOUN
fnp-2845	208	42	of	of	ADP
fnp-2845	208	43	ad	ad	NOUN
fnp-2845	208	44	cases	case	NOUN
fnp-2845	208	45	.	.	PUNCT
fnp-2845	209	1	moreover	moreover	ADV
fnp-2845	209	2	,	,	PUNCT
fnp-2845	209	3	a	a	DET
fnp-2845	209	4	higher	high	ADJ
fnp-2845	209	5	percentage	percentage	NOUN
fnp-2845	209	6	of	of	ADP
fnp-2845	209	7	plaques	plaque	NOUN
fnp-2845	209	8	contained	contain	VERB
fnp-2845	209	9	clusters	cluster	NOUN
fnp-2845	209	10	of	of	ADP
fnp-2845	209	11	microglia	microglia	NOUN
fnp-2845	209	12	in	in	ADP
fnp-2845	209	13	hpcs	hpc	NOUN
fnp-2845	209	14	than	than	ADP
fnp-2845	209	15	in	in	ADP
fnp-2845	209	16	ad	ad	NOUN
fnp-2845	209	17	cases	case	NOUN
fnp-2845	209	18	and	and	CCONJ
fnp-2845	209	19	also	also	ADV
fnp-2845	209	20	a	a	DET
fnp-2845	209	21	portion	portion	NOUN
fnp-2845	209	22	of	of	ADP
fnp-2845	209	23	microglia	microglia	ADJ
fnp-2845	209	24	clusters	cluster	NOUN
fnp-2845	209	25	that	that	PRON
fnp-2845	209	26	were	be	AUX
fnp-2845	209	27	not	not	PART
fnp-2845	209	28	spatially	spatially	ADV
fnp-2845	209	29	associated	associate	VERB
fnp-2845	209	30	with	with	ADP
fnp-2845	209	31	aβ	aβ	PROPN
fnp-2845	209	32	.	.	PUNCT
fnp-2845	210	1	the	the	DET
fnp-2845	210	2	presence	presence	NOUN
fnp-2845	210	3	of	of	ADP
fnp-2845	210	4	a	a	DET
fnp-2845	210	5	strong	strong	ADJ
fnp-2845	210	6	microglial	microglial	ADJ
fnp-2845	210	7	clustering	clustering	ADJ
fnp-2845	210	8	response	response	NOUN
fnp-2845	210	9	in	in	ADP
fnp-2845	210	10	the	the	DET
fnp-2845	210	11	pmc	pmc	NOUN
fnp-2845	210	12	of	of	ADP
fnp-2845	210	13	ad	ad	NOUN
fnp-2845	210	14	cases	case	NOUN
fnp-2845	210	15	and	and	CCONJ
fnp-2845	210	16	in	in	ADP
fnp-2845	210	17	the	the	DET
fnp-2845	210	18	hpcs	hpc	NOUN
fnp-2845	210	19	aligns	align	VERB
fnp-2845	210	20	with	with	ADP
fnp-2845	210	21	pet	pet	ADJ
fnp-2845	210	22	imaging	imaging	NOUN
fnp-2845	210	23	studies	study	NOUN
fnp-2845	210	24	demonstrating	demonstrate	VERB
fnp-2845	210	25	early	early	ADJ
fnp-2845	210	26	activation	activation	NOUN
fnp-2845	210	27	of	of	ADP
fnp-2845	210	28	microglia	microglia	NOUN
fnp-2845	210	29	in	in	ADP
fnp-2845	210	30	preclinical	preclinical	ADJ
fnp-2845	210	31	ad	ad	NOUN
fnp-2845	210	32	cases	case	NOUN
fnp-2845	210	33	(	(	PUNCT
fnp-2845	210	34	49	49	NUM
fnp-2845	210	35	)	)	PUNCT
fnp-2845	210	36	.	.	PUNCT
fnp-2845	211	1	although	although	SCONJ
fnp-2845	211	2	the	the	DET
fnp-2845	211	3	presence	presence	NOUN
fnp-2845	211	4	of	of	ADP
fnp-2845	211	5	clusters	cluster	NOUN
fnp-2845	211	6	unrelated	unrelated	ADJ
fnp-2845	211	7	to	to	ADP
fnp-2845	211	8	aβ	aβ	PRON
fnp-2845	211	9	pathology	pathology	NOUN
fnp-2845	211	10	may	may	AUX
fnp-2845	211	11	be	be	AUX
fnp-2845	211	12	a	a	DET
fnp-2845	211	13	non	non	ADJ
fnp-2845	211	14	-	-	ADJ
fnp-2845	211	15	specific	specific	ADJ
fnp-2845	211	16	observation	observation	NOUN
fnp-2845	211	17	,	,	PUNCT
fnp-2845	211	18	it	it	PRON
fnp-2845	211	19	is	be	AUX
fnp-2845	211	20	interesting	interesting	ADJ
fnp-2845	211	21	to	to	PART
fnp-2845	211	22	note	note	VERB
fnp-2845	211	23	that	that	SCONJ
fnp-2845	211	24	a	a	DET
fnp-2845	211	25	previous	previous	ADJ
fnp-2845	211	26	animal	animal	NOUN
fnp-2845	211	27	study	study	NOUN
fnp-2845	211	28	using	use	VERB
fnp-2845	211	29	a	a	DET
fnp-2845	211	30	5×fad	5×fad	NUM
fnp-2845	211	31	model	model	NOUN
fnp-2845	211	32	also	also	ADV
fnp-2845	211	33	reported	report	VERB
fnp-2845	211	34	the	the	DET
fnp-2845	211	35	presence	presence	NOUN
fnp-2845	211	36	of	of	ADP
fnp-2845	211	37	microgliosis	microgliosis	NOUN
fnp-2845	211	38	prior	prior	ADV
fnp-2845	211	39	to	to	ADP
fnp-2845	211	40	the	the	DET
fnp-2845	211	41	formation	formation	NOUN
fnp-2845	211	42	of	of	ADP
fnp-2845	211	43	insoluble	insoluble	ADJ
fnp-2845	211	44	aβ	aβ	PRON
fnp-2845	211	45	plaques	plaque	NOUN
fnp-2845	211	46	(	(	PUNCT
fnp-2845	211	47	50	50	NUM
fnp-2845	211	48	)	)	PUNCT
fnp-2845	211	49	,	,	PUNCT
fnp-2845	211	50	with	with	ADP
fnp-2845	211	51	another	another	DET
fnp-2845	211	52	mouse	mouse	NOUN
fnp-2845	211	53	model	model	NOUN
fnp-2845	211	54	also	also	ADV
fnp-2845	211	55	indicating	indicate	VERB
fnp-2845	211	56	microglial	microglial	ADJ
fnp-2845	211	57	activation	activation	NOUN
fnp-2845	211	58	in	in	ADP
fnp-2845	211	59	relation	relation	NOUN
fnp-2845	211	60	to	to	ADP
fnp-2845	211	61	synaptic	synaptic	ADJ
fnp-2845	211	62	dysfunction	dysfunction	NOUN
fnp-2845	211	63	prior	prior	ADV
fnp-2845	211	64	to	to	ADP
fnp-2845	211	65	aβ	aβ	NOUN
fnp-2845	211	66	deposition	deposition	NOUN
fnp-2845	211	67	(	(	PUNCT
fnp-2845	211	68	51	51	NUM
fnp-2845	211	69	)	)	PUNCT
fnp-2845	211	70	.	.	PUNCT
fnp-2845	212	1	here	here	ADV
fnp-2845	212	2	it	it	PRON
fnp-2845	212	3	is	be	AUX
fnp-2845	212	4	suggested	suggest	VERB
fnp-2845	212	5	that	that	SCONJ
fnp-2845	212	6	clusters	cluster	NOUN
fnp-2845	212	7	of	of	ADP
fnp-2845	212	8	activated	activated	ADJ
fnp-2845	212	9	microglia	microglia	NOUN
fnp-2845	212	10	in	in	ADP
fnp-2845	212	11	the	the	DET
fnp-2845	212	12	pmc	pmc	PROPN
fnp-2845	212	13	represent	represent	VERB
fnp-2845	212	14	a	a	DET
fnp-2845	212	15	neuroprotective	neuroprotective	ADJ
fnp-2845	212	16	response	response	NOUN
fnp-2845	212	17	correlating	correlate	VERB
fnp-2845	212	18	with	with	ADP
fnp-2845	212	19	the	the	DET
fnp-2845	212	20	deposition	deposition	NOUN
fnp-2845	212	21	of	of	ADP
fnp-2845	212	22	aβ	aβ	NOUN
fnp-2845	212	23	.	.	PUNCT
fnp-2845	213	1	we	we	PRON
fnp-2845	213	2	have	have	AUX
fnp-2845	213	3	demonstrated	demonstrate	VERB
fnp-2845	213	4	clusters	cluster	NOUN
fnp-2845	213	5	of	of	ADP
fnp-2845	213	6	activated	activated	ADJ
fnp-2845	213	7	microglia	microglia	NOUN
fnp-2845	213	8	that	that	PRON
fnp-2845	213	9	display	display	VERB
fnp-2845	213	10	phagocytic	phagocytic	ADJ
fnp-2845	213	11	capabilities	capability	NOUN
fnp-2845	213	12	in	in	ADP
fnp-2845	213	13	the	the	DET
fnp-2845	213	14	mildly	mildly	ADV
fnp-2845	213	15	affected	affect	VERB
fnp-2845	213	16	pmc	pmc	PROPN
fnp-2845	213	17	before	before	ADP
fnp-2845	213	18	the	the	DET
fnp-2845	213	19	development	development	NOUN
fnp-2845	213	20	of	of	ADP
fnp-2845	213	21	extensive	extensive	ADJ
fnp-2845	213	22	tau	tau	PROPN
fnp-2845	213	23	pathology	pathology	NOUN
fnp-2845	213	24	.	.	PUNCT
fnp-2845	214	1	it	it	PRON
fnp-2845	214	2	is	be	AUX
fnp-2845	214	3	conceivable	conceivable	ADJ
fnp-2845	214	4	that	that	SCONJ
fnp-2845	214	5	once	once	SCONJ
fnp-2845	214	6	the	the	DET
fnp-2845	214	7	phagocytic	phagocytic	ADJ
fnp-2845	214	8	potential	potential	NOUN
fnp-2845	214	9	of	of	ADP
fnp-2845	214	10	microglia	microglia	NOUN
fnp-2845	214	11	is	be	AUX
fnp-2845	214	12	overwhelmed	overwhelmed	ADJ
fnp-2845	214	13	,	,	PUNCT
fnp-2845	214	14	a	a	DET
fnp-2845	214	15	transition	transition	NOUN
fnp-2845	214	16	to	to	ADP
fnp-2845	214	17	a	a	DET
fnp-2845	214	18	more	more	ADV
fnp-2845	214	19	neurotoxic	neurotoxic	ADJ
fnp-2845	214	20	proinflammatory	proinflammatory	ADJ
fnp-2845	214	21	phenotype	phenotype	NOUN
fnp-2845	214	22	occurs	occur	VERB
fnp-2845	214	23	and	and	CCONJ
fnp-2845	214	24	that	that	SCONJ
fnp-2845	214	25	this	this	PRON
fnp-2845	214	26	represents	represent	VERB
fnp-2845	214	27	a	a	DET
fnp-2845	214	28	pivotal	pivotal	ADJ
fnp-2845	214	29	moment	moment	NOUN
fnp-2845	214	30	preceding	precede	VERB
fnp-2845	214	31	tau	tau	PROPN
fnp-2845	214	32	-	-	PUNCT
fnp-2845	214	33	related	relate	VERB
fnp-2845	214	34	neurofibrillary	neurofibrillary	ADJ
fnp-2845	214	35	degeneration	degeneration	NOUN
fnp-2845	214	36	.	.	PUNCT
fnp-2845	215	1	studies	study	NOUN
fnp-2845	215	2	in	in	ADP
fnp-2845	215	3	mouse	mouse	NOUN
fnp-2845	215	4	models	model	NOUN
fnp-2845	215	5	of	of	ADP
fnp-2845	215	6	aβ	aβ	PRON
fnp-2845	215	7	overexpression	overexpression	NOUN
fnp-2845	215	8	suggest	suggest	VERB
fnp-2845	215	9	proinflammatory	proinflammatory	ADJ
fnp-2845	215	10	microglia	microglia	NOUN
fnp-2845	215	11	,	,	PUNCT
fnp-2845	215	12	which	which	PRON
fnp-2845	215	13	may	may	AUX
fnp-2845	215	14	be	be	AUX
fnp-2845	215	15	induced	induce	VERB
fnp-2845	215	16	by	by	ADP
fnp-2845	215	17	the	the	DET
fnp-2845	215	18	binding	binding	NOUN
fnp-2845	215	19	of	of	ADP
fnp-2845	215	20	oligomeric	oligomeric	ADJ
fnp-2845	215	21	and	and	CCONJ
fnp-2845	215	22	fibrillar	fibrillar	ADJ
fnp-2845	216	1	aβ	aβ	NOUN
fnp-2845	216	2	species	specie	NOUN
fnp-2845	216	3	to	to	ADP
fnp-2845	216	4	nlr	nlr	PROPN
fnp-2845	216	5	family	family	PROPN
fnp-2845	216	6	pyrin	pyrin	NOUN
fnp-2845	216	7	domain	domain	NOUN
fnp-2845	216	8	containing	contain	VERB
fnp-2845	216	9	3	3	NUM
fnp-2845	216	10	,	,	PUNCT
fnp-2845	216	11	receptor	receptor	NOUN
fnp-2845	216	12	for	for	ADP
fnp-2845	216	13	advanced	advanced	ADJ
fnp-2845	216	14	glycation	glycation	NOUN
fnp-2845	216	15	endproducts	endproduct	NOUN
fnp-2845	216	16	,	,	PUNCT
fnp-2845	216	17	scavenger	scavenger	NOUN
fnp-2845	216	18	receptors	receptor	NOUN
fnp-2845	216	19	,	,	PUNCT
fnp-2845	216	20	and	and	CCONJ
fnp-2845	216	21	toll	toll	NOUN
fnp-2845	216	22	-	-	PUNCT
fnp-2845	216	23	like	like	ADJ
fnp-2845	216	24	receptors	receptor	NOUN
fnp-2845	216	25	,	,	PUNCT
fnp-2845	216	26	among	among	ADP
fnp-2845	216	27	others	other	NOUN
fnp-2845	216	28	(	(	PUNCT
fnp-2845	216	29	52	52	NUM
fnp-2845	216	30	-	-	SYM
fnp-2845	216	31	58	58	NUM
fnp-2845	216	32	)	)	PUNCT
fnp-2845	216	33	,	,	PUNCT
fnp-2845	216	34	are	be	AUX
fnp-2845	216	35	associated	associate	VERB
fnp-2845	216	36	with	with	ADP
fnp-2845	216	37	poorer	poor	ADJ
fnp-2845	216	38	cognitive	cognitive	ADJ
fnp-2845	216	39	and	and	CCONJ
fnp-2845	216	40	survival	survival	NOUN
fnp-2845	216	41	outcomes	outcome	NOUN
fnp-2845	216	42	,	,	PUNCT
fnp-2845	216	43	have	have	AUX
fnp-2845	216	44	impaired	impair	VERB
fnp-2845	216	45	phagocytic	phagocytic	ADJ
fnp-2845	216	46	capabilities	capability	NOUN
fnp-2845	216	47	(	(	PUNCT
fnp-2845	216	48	59	59	NUM
fnp-2845	216	49	)	)	PUNCT
fnp-2845	216	50	,	,	PUNCT
fnp-2845	216	51	and	and	CCONJ
fnp-2845	216	52	are	be	AUX
fnp-2845	216	53	capable	capable	ADJ
fnp-2845	216	54	of	of	ADP
fnp-2845	216	55	secreting	secrete	VERB
fnp-2845	216	56	an	an	DET
fnp-2845	216	57	expansive	expansive	ADJ
fnp-2845	216	58	complement	complement	NOUN
fnp-2845	216	59	of	of	ADP
fnp-2845	216	60	neurotoxic	neurotoxic	ADJ
fnp-2845	216	61	compounds	compound	NOUN
fnp-2845	216	62	including	include	VERB
fnp-2845	216	63	reactive	reactive	ADJ
fnp-2845	216	64	oxygen	oxygen	NOUN
fnp-2845	216	65	species	specie	NOUN
fnp-2845	216	66	,	,	PUNCT
fnp-2845	216	67	nitric	nitric	ADJ
fnp-2845	216	68	oxide	oxide	NOUN
fnp-2845	216	69	,	,	PUNCT
fnp-2845	216	70	peroxynitrite	peroxynitrite	ADJ
fnp-2845	216	71	,	,	PUNCT
fnp-2845	216	72	tumour	tumour	NOUN
fnp-2845	216	73	necrosis	necrosis	NOUN
fnp-2845	216	74	factor	factor	NOUN
fnp-2845	216	75	α	α	NOUN
fnp-2845	216	76	,	,	PUNCT
fnp-2845	216	77	interleukin	interleukin	NOUN
fnp-2845	216	78	1	1	NUM
fnp-2845	216	79	β	β	NOUN
fnp-2845	216	80	,	,	PUNCT
fnp-2845	216	81	and	and	CCONJ
fnp-2845	216	82	prostaglandin	prostaglandin	NOUN
fnp-2845	216	83	-	-	PUNCT
fnp-2845	216	84	e2	e2	NOUN
fnp-2845	216	85	(	(	PUNCT
fnp-2845	216	86	60	60	NUM
fnp-2845	216	87	)	)	PUNCT
fnp-2845	216	88	.	.	PUNCT
fnp-2845	217	1	however	however	ADV
fnp-2845	217	2	aβ	aβ	NOUN
fnp-2845	217	3	-	-	PUNCT
fnp-2845	217	4	independent	independent	ADJ
fnp-2845	217	5	mechanisms	mechanism	NOUN
fnp-2845	217	6	of	of	ADP
fnp-2845	217	7	microglia	microglia	ADJ
fnp-2845	217	8	activation	activation	NOUN
fnp-2845	217	9	or	or	CCONJ
fnp-2845	217	10	exhaustion	exhaustion	NOUN
fnp-2845	217	11	in	in	ADP
fnp-2845	217	12	human	human	ADJ
fnp-2845	217	13	ad	ad	NOUN
fnp-2845	217	14	can	can	AUX
fnp-2845	217	15	not	not	PART
fnp-2845	217	16	be	be	AUX
fnp-2845	217	17	excluded	exclude	VERB
fnp-2845	217	18	and	and	CCONJ
fnp-2845	217	19	require	require	VERB
fnp-2845	217	20	further	further	ADJ
fnp-2845	217	21	research	research	NOUN
fnp-2845	217	22	considering	consider	VERB
fnp-2845	217	23	the	the	DET
fnp-2845	217	24	so	so	ADV
fnp-2845	217	25	far	far	ADV
fnp-2845	217	26	limited	limited	ADJ
fnp-2845	217	27	efficacy	efficacy	NOUN
fnp-2845	217	28	of	of	ADP
fnp-2845	217	29	the	the	DET
fnp-2845	217	30	pharmacological	pharmacological	ADJ
fnp-2845	217	31	clearance	clearance	NOUN
fnp-2845	217	32	of	of	ADP
fnp-2845	217	33	aβ	aβ	PRON
fnp-2845	217	34	in	in	ADP
fnp-2845	217	35	clinical	clinical	ADJ
fnp-2845	217	36	trials	trial	NOUN
fnp-2845	217	37	(	(	PUNCT
fnp-2845	217	38	61	61	NUM
fnp-2845	217	39	,	,	PUNCT
fnp-2845	217	40	62	62	NUM
fnp-2845	217	41	)	)	PUNCT
fnp-2845	217	42	.	.	PUNCT
fnp-2845	218	1	activated	activate	VERB
fnp-2845	218	2	microglia	microglia	NOUN
fnp-2845	218	3	tended	tend	VERB
fnp-2845	218	4	to	to	PART
fnp-2845	218	5	be	be	AUX
fnp-2845	218	6	associated	associate	VERB
fnp-2845	218	7	with	with	ADP
fnp-2845	218	8	fibrillar	fibrillar	ADJ
fnp-2845	218	9	nps	nps	PROPN
fnp-2845	218	10	,	,	PUNCT
fnp-2845	218	11	and	and	CCONJ
fnp-2845	218	12	higher	high	ADJ
fnp-2845	218	13	resolution	resolution	NOUN
fnp-2845	218	14	confocal	confocal	ADJ
fnp-2845	218	15	photomicrographs	photomicrograph	NOUN
fnp-2845	218	16	showed	show	VERB
fnp-2845	218	17	evidence	evidence	NOUN
fnp-2845	218	18	of	of	ADP
fnp-2845	218	19	aβ	aβ	DET
fnp-2845	218	20	internalisation	internalisation	NOUN
fnp-2845	218	21	by	by	ADP
fnp-2845	218	22	microglia	microglia	NOUN
fnp-2845	218	23	in	in	ADP
fnp-2845	218	24	both	both	DET
fnp-2845	218	25	regions	region	NOUN
fnp-2845	218	26	.	.	PUNCT
fnp-2845	219	1	the	the	DET
fnp-2845	219	2	latter	latter	ADJ
fnp-2845	219	3	may	may	AUX
fnp-2845	219	4	explain	explain	VERB
fnp-2845	219	5	the	the	DET
fnp-2845	219	6	remnant	remnant	ADJ
fnp-2845	219	7	plaques	plaque	NOUN
fnp-2845	219	8	observed	observe	VERB
fnp-2845	219	9	here	here	ADV
fnp-2845	219	10	(	(	PUNCT
fnp-2845	219	11	that	that	PRON
fnp-2845	219	12	contain	contain	VERB
fnp-2845	219	13	weak	weak	ADJ
fnp-2845	219	14	or	or	CCONJ
fnp-2845	219	15	absent	absent	ADJ
fnp-2845	219	16	aβ	aβ	NOUN
fnp-2845	219	17	-	-	PUNCT
fnp-2845	219	18	immunolabelling	immunolabelling	NOUN
fnp-2845	219	19	;	;	PUNCT
fnp-2845	219	20	in	in	ADP
fnp-2845	219	21	which	which	PRON
fnp-2845	219	22	higher	high	ADJ
fnp-2845	219	23	levels	level	NOUN
fnp-2845	219	24	of	of	ADP
fnp-2845	219	25	aβ	aβ	PRON
fnp-2845	219	26	were	be	AUX
fnp-2845	219	27	associated	associate	VERB
fnp-2845	219	28	with	with	ADP
fnp-2845	219	29	activated	activated	ADJ
fnp-2845	219	30	microglia	microglia	NOUN
fnp-2845	219	31	,	,	PUNCT
fnp-2845	219	32	but	but	CCONJ
fnp-2845	219	33	dystrophic	dystrophic	ADJ
fnp-2845	219	34	microglia	microglia	NOUN
fnp-2845	219	35	where	where	SCONJ
fnp-2845	219	36	aβ	aβ	NOUN
fnp-2845	219	37	-	-	PUNCT
fnp-2845	219	38	immunoreactivity	immunoreactivity	NOUN
fnp-2845	219	39	was	be	AUX
fnp-2845	219	40	very	very	ADV
fnp-2845	219	41	minimal	minimal	ADJ
fnp-2845	219	42	or	or	CCONJ
fnp-2845	219	43	absent	absent	ADJ
fnp-2845	219	44	,	,	PUNCT
fnp-2845	219	45	particularly	particularly	ADV
fnp-2845	219	46	where	where	SCONJ
fnp-2845	219	47	dystrophic	dystrophic	ADJ
fnp-2845	219	48	neurites	neurite	NOUN
fnp-2845	219	49	were	be	AUX
fnp-2845	219	50	extensive	extensive	ADJ
fnp-2845	219	51	)	)	PUNCT
fnp-2845	219	52	and	and	CCONJ
fnp-2845	219	53	described	describe	VERB
fnp-2845	219	54	elsewhere	elsewhere	ADV
fnp-2845	219	55	(	(	PUNCT
fnp-2845	219	56	14	14	NUM
fnp-2845	219	57	)	)	PUNCT
fnp-2845	219	58	and	and	CCONJ
fnp-2845	219	59	is	be	AUX
fnp-2845	219	60	potentially	potentially	ADV
fnp-2845	219	61	relevant	relevant	ADJ
fnp-2845	219	62	to	to	ADP
fnp-2845	219	63	the	the	DET
fnp-2845	219	64	proposed	propose	VERB
fnp-2845	219	65	dynamic	dynamic	ADJ
fnp-2845	219	66	equilibrium	equilibrium	NOUN
fnp-2845	219	67	between	between	ADP
fnp-2845	219	68	soluble	soluble	ADJ
fnp-2845	219	69	aβ	aβ	NOUN
fnp-2845	219	70	oligomers	oligomer	NOUN
fnp-2845	219	71	and	and	CCONJ
fnp-2845	219	72	insoluble	insoluble	ADJ
fnp-2845	219	73	fibrils	fibril	NOUN
fnp-2845	219	74	(	(	PUNCT
fnp-2845	219	75	63	63	NUM
fnp-2845	219	76	)	)	PUNCT
fnp-2845	219	77	.	.	PUNCT
fnp-2845	220	1	however	however	ADV
fnp-2845	220	2	,	,	PUNCT
fnp-2845	220	3	it	it	PRON
fnp-2845	220	4	will	will	AUX
fnp-2845	220	5	be	be	AUX
fnp-2845	220	6	important	important	ADJ
fnp-2845	220	7	to	to	PART
fnp-2845	220	8	confirm	confirm	VERB
fnp-2845	220	9	the	the	DET
fnp-2845	220	10	internalisation	internalisation	NOUN
fnp-2845	220	11	of	of	ADP
fnp-2845	220	12	aβ	aβ	NOUN
fnp-2845	220	13	by	by	ADP
fnp-2845	220	14	microglia	microglia	NOUN
fnp-2845	220	15	with	with	ADP
fnp-2845	220	16	super	super	ADJ
fnp-2845	220	17	resolution	resolution	NOUN
fnp-2845	220	18	techniques	technique	NOUN
fnp-2845	220	19	such	such	ADJ
fnp-2845	220	20	as	as	ADP
fnp-2845	220	21	direct	direct	ADJ
fnp-2845	220	22	stochastic	stochastic	ADJ
fnp-2845	220	23	optical	optical	ADJ
fnp-2845	220	24	reconstruction	reconstruction	NOUN
fnp-2845	220	25	microscopy	microscopy	NOUN
fnp-2845	220	26	(	(	PUNCT
fnp-2845	220	27	dstorm	dstorm	NOUN
fnp-2845	220	28	)	)	PUNCT
fnp-2845	220	29	.	.	PUNCT
fnp-2845	221	1	in	in	ADP
fnp-2845	221	2	contrast	contrast	NOUN
fnp-2845	221	3	,	,	PUNCT
fnp-2845	221	4	microglia	microglia	NOUN
fnp-2845	221	5	did	do	AUX
fnp-2845	221	6	not	not	PART
fnp-2845	221	7	specifically	specifically	ADV
fnp-2845	221	8	cluster	cluster	VERB
fnp-2845	221	9	around	around	ADP
fnp-2845	221	10	any	any	PRON
fnp-2845	221	11	of	of	ADP
fnp-2845	221	12	the	the	DET
fnp-2845	221	13	three	three	NUM
fnp-2845	221	14	forms	form	NOUN
fnp-2845	221	15	of	of	ADP
fnp-2845	221	16	tau	tau	PROPN
fnp-2845	221	17	pathology	pathology	NOUN
fnp-2845	221	18	,	,	PUNCT
fnp-2845	221	19	nfts	nft	NOUN
fnp-2845	221	20	,	,	PUNCT
fnp-2845	221	21	nts	nt	NOUN
fnp-2845	221	22	and	and	CCONJ
fnp-2845	221	23	dns	dns	NOUN
fnp-2845	221	24	,	,	PUNCT
fnp-2845	221	25	nor	nor	CCONJ
fnp-2845	221	26	did	do	AUX
fnp-2845	221	27	they	they	PRON
fnp-2845	221	28	appear	appear	VERB
fnp-2845	221	29	to	to	ADP
fnp-2845	221	30	internalise	internalise	PROPN
fnp-2845	221	31	tau	tau	PROPN
fnp-2845	221	32	in	in	ADP
fnp-2845	221	33	co	co	NOUN
fnp-2845	221	34	-	-	NOUN
fnp-2845	221	35	localisation	localisation	ADJ
fnp-2845	221	36	studies	study	NOUN
fnp-2845	221	37	,	,	PUNCT
fnp-2845	221	38	although	although	SCONJ
fnp-2845	221	39	processes	process	NOUN
fnp-2845	221	40	of	of	ADP
fnp-2845	221	41	microglia	microglia	NOUN
fnp-2845	221	42	were	be	AUX
fnp-2845	221	43	coincidentally	coincidentally	ADV
fnp-2845	221	44	found	find	VERB
fnp-2845	221	45	adjacent	adjacent	ADJ
fnp-2845	221	46	to	to	ADP
fnp-2845	221	47	dns	dns	PROPN
fnp-2845	221	48	.	.	PUNCT
fnp-2845	222	1	the	the	DET
fnp-2845	222	2	microglial	microglial	ADJ
fnp-2845	222	3	clustering	clustering	ADJ
fnp-2845	222	4	response	response	NOUN
fnp-2845	222	5	dissipated	dissipate	VERB
fnp-2845	222	6	over	over	ADP
fnp-2845	222	7	the	the	DET
fnp-2845	222	8	modelled	model	VERB
fnp-2845	222	9	disease	disease	NOUN
fnp-2845	222	10	course	course	NOUN
fnp-2845	222	11	with	with	ADP
fnp-2845	222	12	advanced	advanced	ADJ
fnp-2845	222	13	stages	stage	NOUN
fnp-2845	222	14	,	,	PUNCT
fnp-2845	222	15	represented	represent	VERB
fnp-2845	222	16	by	by	ADP
fnp-2845	222	17	the	the	DET
fnp-2845	222	18	itc	itc	PROPN
fnp-2845	222	19	of	of	ADP
fnp-2845	222	20	ad	ad	NOUN
fnp-2845	222	21	cases	case	NOUN
fnp-2845	222	22	,	,	PUNCT
fnp-2845	222	23	being	be	AUX
fnp-2845	222	24	characterised	characterise	VERB
fnp-2845	222	25	by	by	ADP
fnp-2845	222	26	reduced	reduced	ADJ
fnp-2845	222	27	iba1	iba1	PROPN
fnp-2845	222	28	immunoreactivity	immunoreactivity	NOUN
fnp-2845	222	29	,	,	PUNCT
fnp-2845	222	30	as	as	SCONJ
fnp-2845	222	31	reported	report	VERB
fnp-2845	222	32	elsewhere	elsewhere	ADV
fnp-2845	222	33	(	(	PUNCT
fnp-2845	222	34	31	31	NUM
fnp-2845	222	35	,	,	PUNCT
fnp-2845	222	36	64	64	NUM
fnp-2845	222	37	)	)	PUNCT
fnp-2845	222	38	.	.	PUNCT
fnp-2845	223	1	this	this	PRON
fnp-2845	223	2	suggests	suggest	VERB
fnp-2845	223	3	a	a	DET
fnp-2845	223	4	process	process	NOUN
fnp-2845	223	5	of	of	ADP
fnp-2845	223	6	microglial	microglial	ADJ
fnp-2845	223	7	incapacitation	incapacitation	NOUN
fnp-2845	223	8	in	in	ADP
fnp-2845	223	9	the	the	DET
fnp-2845	223	10	context	context	NOUN
fnp-2845	223	11	of	of	ADP
fnp-2845	223	12	increased	increase	VERB
fnp-2845	223	13	tau	tau	PROPN
fnp-2845	223	14	load	load	NOUN
fnp-2845	223	15	,	,	PUNCT
fnp-2845	223	16	a	a	DET
fnp-2845	223	17	concept	concept	NOUN
fnp-2845	223	18	which	which	PRON
fnp-2845	223	19	is	be	AUX
fnp-2845	223	20	supported	support	VERB
fnp-2845	223	21	by	by	ADP
fnp-2845	223	22	a	a	DET
fnp-2845	223	23	growing	grow	VERB
fnp-2845	223	24	body	body	NOUN
fnp-2845	223	25	of	of	ADP
fnp-2845	223	26	literature	literature	NOUN
fnp-2845	223	27	(	(	PUNCT
fnp-2845	223	28	65	65	NUM
fnp-2845	223	29	,	,	PUNCT
fnp-2845	223	30	66	66	NUM
fnp-2845	223	31	)	)	PUNCT
fnp-2845	223	32	.	.	PUNCT
fnp-2845	224	1	from	from	ADP
fnp-2845	224	2	these	these	DET
fnp-2845	224	3	results	result	NOUN
fnp-2845	224	4	it	it	PRON
fnp-2845	224	5	is	be	AUX
fnp-2845	224	6	hypothesised	hypothesise	VERB
fnp-2845	224	7	that	that	SCONJ
fnp-2845	224	8	the	the	DET
fnp-2845	224	9	activation	activation	NOUN
fnp-2845	224	10	of	of	ADP
fnp-2845	224	11	microglia	microglia	NOUN
fnp-2845	224	12	coincides	coincide	NOUN
fnp-2845	224	13	with	with	ADP
fnp-2845	224	14	cortical	cortical	ADJ
fnp-2845	224	15	aβ	aβ	NOUN
fnp-2845	224	16	deposition	deposition	NOUN
fnp-2845	224	17	.	.	PUNCT
fnp-2845	225	1	neuritic	neuritic	ADJ
fnp-2845	225	2	inclusions	inclusion	NOUN
fnp-2845	225	3	of	of	ADP
fnp-2845	225	4	tau	tau	PROPN
fnp-2845	225	5	in	in	ADP
fnp-2845	225	6	the	the	DET
fnp-2845	225	7	cortex	cortex	NOUN
fnp-2845	225	8	are	be	AUX
fnp-2845	225	9	evident	evident	ADJ
fnp-2845	225	10	early	early	ADV
fnp-2845	225	11	in	in	ADP
fnp-2845	225	12	the	the	DET
fnp-2845	225	13	disease	disease	NOUN
fnp-2845	225	14	process	process	NOUN
fnp-2845	225	15	,	,	PUNCT
fnp-2845	225	16	represented	represent	VERB
fnp-2845	225	17	here	here	ADV
fnp-2845	225	18	by	by	ADP
fnp-2845	225	19	the	the	DET
fnp-2845	225	20	pmc	pmc	PROPN
fnp-2845	225	21	of	of	ADP
fnp-2845	225	22	ad	ad	NOUN
fnp-2845	225	23	cases	case	NOUN
fnp-2845	225	24	,	,	PUNCT
fnp-2845	225	25	but	but	CCONJ
fnp-2845	225	26	mainly	mainly	ADV
fnp-2845	225	27	develop	develop	VERB
fnp-2845	225	28	after	after	ADP
fnp-2845	225	29	the	the	DET
fnp-2845	225	30	deposition	deposition	NOUN
fnp-2845	225	31	aβ	aβ	NOUN
fnp-2845	225	32	and	and	CCONJ
fnp-2845	225	33	the	the	DET
fnp-2845	225	34	activation	activation	NOUN
fnp-2845	225	35	of	of	ADP
fnp-2845	225	36	microglia	microglia	NOUN
fnp-2845	225	37	.	.	PUNCT
fnp-2845	226	1	this	this	DET
fnp-2845	226	2	sequence	sequence	NOUN
fnp-2845	226	3	of	of	ADP
fnp-2845	226	4	pathological	pathological	ADJ
fnp-2845	226	5	changes	change	NOUN
fnp-2845	226	6	is	be	AUX
fnp-2845	226	7	ostensibly	ostensibly	ADV
fnp-2845	226	8	consistent	consistent	ADJ
fnp-2845	226	9	with	with	ADP
fnp-2845	226	10	the	the	DET
fnp-2845	226	11	amyloid	amyloid	NOUN
fnp-2845	226	12	cascade	cascade	NOUN
fnp-2845	226	13	hypothesis	hypothesis	NOUN
fnp-2845	226	14	for	for	ADP
fnp-2845	226	15	ad	ad	NOUN
fnp-2845	226	16	pathogenesis	pathogenesis	NOUN
fnp-2845	226	17	(	(	PUNCT
fnp-2845	226	18	19	19	NUM
fnp-2845	226	19	)	)	PUNCT
fnp-2845	226	20	given	give	VERB
fnp-2845	226	21	the	the	DET
fnp-2845	226	22	presence	presence	NOUN
fnp-2845	226	23	of	of	ADP
fnp-2845	226	24	elevated	elevated	ADJ
fnp-2845	226	25	aβ	aβ	NOUN
fnp-2845	226	26	in	in	ADP
fnp-2845	226	27	the	the	DET
fnp-2845	226	28	pmc	pmc	PROPN
fnp-2845	226	29	of	of	ADP
fnp-2845	226	30	hpcs	hpc	NOUN
fnp-2845	226	31	,	,	PUNCT
fnp-2845	226	32	however	however	ADV
fnp-2845	226	33	it	it	PRON
fnp-2845	226	34	should	should	AUX
fnp-2845	226	35	be	be	AUX
fnp-2845	226	36	stressed	stress	VERB
fnp-2845	226	37	that	that	SCONJ
fnp-2845	226	38	the	the	DET
fnp-2845	226	39	levels	level	NOUN
fnp-2845	226	40	of	of	ADP
fnp-2845	226	41	aβ	aβ	PRON
fnp-2845	226	42	and	and	CCONJ
fnp-2845	226	43	tau	tau	PROPN
fnp-2845	226	44	pathology	pathology	NOUN
fnp-2845	226	45	were	be	AUX
fnp-2845	226	46	present	present	ADJ
fnp-2845	226	47	at	at	ADP
fnp-2845	226	48	similar	similar	ADJ
fnp-2845	226	49	levels	level	NOUN
fnp-2845	226	50	in	in	ADP
fnp-2845	226	51	the	the	DET
fnp-2845	226	52	pmc	pmc	PROPN
fnp-2845	226	53	of	of	ADP
fnp-2845	226	54	confirmed	confirm	VERB
fnp-2845	226	55	ad	ad	NOUN
fnp-2845	226	56	cases	case	NOUN
fnp-2845	226	57	.	.	PUNCT
fnp-2845	227	1	therefore	therefore	ADV
fnp-2845	227	2	it	it	PRON
fnp-2845	227	3	could	could	AUX
fnp-2845	227	4	be	be	AUX
fnp-2845	227	5	argued	argue	VERB
fnp-2845	227	6	that	that	SCONJ
fnp-2845	227	7	insoluble	insoluble	ADJ
fnp-2845	227	8	aβ	aβ	NOUN
fnp-2845	227	9	and	and	CCONJ
fnp-2845	227	10	tau	tau	PROPN
fnp-2845	227	11	deposits	deposit	NOUN
fnp-2845	227	12	begin	begin	VERB
fnp-2845	227	13	forming	form	VERB
fnp-2845	227	14	concurrently	concurrently	ADV
fnp-2845	227	15	in	in	ADP
fnp-2845	227	16	the	the	DET
fnp-2845	227	17	cerebral	cerebral	ADJ
fnp-2845	227	18	cortex	cortex	NOUN
fnp-2845	227	19	of	of	ADP
fnp-2845	227	20	ad	ad	NOUN
fnp-2845	227	21	brains	brain	NOUN
fnp-2845	227	22	.	.	PUNCT
fnp-2845	228	1	this	this	PRON
fnp-2845	228	2	would	would	AUX
fnp-2845	228	3	be	be	AUX
fnp-2845	228	4	consistent	consistent	ADJ
fnp-2845	228	5	with	with	ADP
fnp-2845	228	6	those	those	PRON
fnp-2845	228	7	arguing	argue	VERB
fnp-2845	228	8	in	in	ADP
fnp-2845	228	9	favour	favour	NOUN
fnp-2845	228	10	of	of	ADP
fnp-2845	228	11	the	the	DET
fnp-2845	228	12	pathogenetic	pathogenetic	ADJ
fnp-2845	228	13	importance	importance	NOUN
fnp-2845	228	14	of	of	ADP
fnp-2845	228	15	tau	tau	PROPN
fnp-2845	228	16	deposition	deposition	NOUN
fnp-2845	228	17	(	(	PUNCT
fnp-2845	228	18	22	22	NUM
fnp-2845	228	19	,	,	PUNCT
fnp-2845	228	20	23	23	NUM
fnp-2845	228	21	,	,	PUNCT
fnp-2845	228	22	67	67	NUM
fnp-2845	228	23	,	,	PUNCT
fnp-2845	228	24	68	68	NUM
fnp-2845	228	25	)	)	PUNCT
fnp-2845	228	26	and	and	CCONJ
fnp-2845	228	27	the	the	DET
fnp-2845	228	28	possibility	possibility	NOUN
fnp-2845	228	29	that	that	SCONJ
fnp-2845	228	30	it	it	PRON
fnp-2845	228	31	in	in	ADP
fnp-2845	228	32	fact	fact	NOUN
fnp-2845	228	33	acts	act	VERB
fnp-2845	228	34	as	as	ADP
fnp-2845	228	35	a	a	DET
fnp-2845	228	36	causative	causative	ADJ
fnp-2845	228	37	factor	factor	NOUN
fnp-2845	228	38	behind	behind	ADP
fnp-2845	228	39	ad	ad	NOUN
fnp-2845	228	40	-	-	PUNCT
fnp-2845	228	41	related	relate	VERB
fnp-2845	228	42	microglial	microglial	ADJ
fnp-2845	228	43	activation	activation	NOUN
fnp-2845	228	44	(	(	PUNCT
fnp-2845	228	45	69	69	NUM
fnp-2845	228	46	)	)	PUNCT
fnp-2845	228	47	.	.	PUNCT
fnp-2845	229	1	certainly	certainly	ADV
fnp-2845	229	2	,	,	PUNCT
fnp-2845	229	3	animal	animal	NOUN
fnp-2845	229	4	models	model	NOUN
fnp-2845	229	5	suggest	suggest	VERB
fnp-2845	229	6	that	that	SCONJ
fnp-2845	229	7	microglial	microglial	ADJ
fnp-2845	229	8	activation	activation	NOUN
fnp-2845	229	9	augments	augment	VERB
fnp-2845	229	10	tau	tau	PROPN
fnp-2845	229	11	pathology	pathology	NOUN
fnp-2845	229	12	and	and	CCONJ
fnp-2845	229	13	specifically	specifically	ADV
fnp-2845	229	14	tau	tau	PROPN
fnp-2845	229	15	phosphorylation	phosphorylation	NOUN
fnp-2845	229	16	(	(	PUNCT
fnp-2845	229	17	70	70	NUM
fnp-2845	229	18	)	)	PUNCT
fnp-2845	229	19	.	.	PUNCT
fnp-2845	230	1	this	this	DET
fnp-2845	230	2	scenario	scenario	NOUN
fnp-2845	230	3	would	would	AUX
fnp-2845	230	4	then	then	ADV
fnp-2845	230	5	be	be	AUX
fnp-2845	230	6	consistent	consistent	ADJ
fnp-2845	230	7	with	with	ADP
fnp-2845	230	8	our	our	PRON
fnp-2845	230	9	observation	observation	NOUN
fnp-2845	230	10	that	that	SCONJ
fnp-2845	230	11	microglial	microglial	ADJ
fnp-2845	230	12	activation	activation	NOUN
fnp-2845	230	13	wanes	wane	VERB
fnp-2845	230	14	with	with	ADP
fnp-2845	230	15	increased	increase	VERB
fnp-2845	230	16	tau	tau	PROPN
fnp-2845	230	17	deposition	deposition	NOUN
fnp-2845	230	18	and	and	CCONJ
fnp-2845	230	19	with	with	ADP
fnp-2845	230	20	the	the	DET
fnp-2845	230	21	idea	idea	NOUN
fnp-2845	230	22	that	that	SCONJ
fnp-2845	230	23	ageing	ageing	NOUN
fnp-2845	230	24	impairs	impair	VERB
fnp-2845	230	25	the	the	DET
fnp-2845	230	26	housekeeping	housekeeping	NOUN
fnp-2845	230	27	functions	function	NOUN
fnp-2845	230	28	of	of	ADP
fnp-2845	230	29	microglia	microglia	NOUN
fnp-2845	230	30	(	(	PUNCT
fnp-2845	230	31	71	71	NUM
fnp-2845	230	32	)	)	PUNCT
fnp-2845	230	33	.	.	PUNCT
fnp-2845	231	1	finally	finally	ADV
fnp-2845	231	2	,	,	PUNCT
fnp-2845	231	3	even	even	ADV
fnp-2845	231	4	in	in	ADP
fnp-2845	231	5	the	the	DET
fnp-2845	231	6	presence	presence	NOUN
fnp-2845	231	7	of	of	ADP
fnp-2845	231	8	extensive	extensive	ADJ
fnp-2845	231	9	tau	tau	PROPN
fnp-2845	231	10	pathology	pathology	NOUN
fnp-2845	231	11	,	,	PUNCT
fnp-2845	231	12	the	the	DET
fnp-2845	231	13	increased	increase	VERB
fnp-2845	231	14	presence	presence	NOUN
fnp-2845	231	15	of	of	ADP
fnp-2845	231	16	remnant	remnant	ADJ
fnp-2845	231	17	plaques	plaque	NOUN
fnp-2845	231	18	in	in	ADP
fnp-2845	231	19	the	the	DET
fnp-2845	231	20	itc	itc	PROPN
fnp-2845	231	21	suggests	suggest	VERB
fnp-2845	231	22	that	that	SCONJ
fnp-2845	231	23	microglia	microglia	NOUN
fnp-2845	231	24	retain	retain	VERB
fnp-2845	231	25	the	the	DET
fnp-2845	231	26	ability	ability	NOUN
fnp-2845	231	27	to	to	PART
fnp-2845	231	28	clear	clear	VERB
fnp-2845	231	29	aβ	aβ	DET
fnp-2845	231	30	peptides	peptide	NOUN
fnp-2845	231	31	.	.	PUNCT
fnp-2845	232	1	understanding	understand	VERB
fnp-2845	232	2	the	the	DET
fnp-2845	232	3	functional	functional	ADJ
fnp-2845	232	4	significance	significance	NOUN
fnp-2845	232	5	of	of	ADP
fnp-2845	232	6	these	these	DET
fnp-2845	232	7	dynamic	dynamic	ADJ
fnp-2845	232	8	spatiotemporal	spatiotemporal	ADJ
fnp-2845	232	9	changes	change	NOUN
fnp-2845	232	10	in	in	ADP
fnp-2845	232	11	microglial	microglial	ADJ
fnp-2845	232	12	activity	activity	NOUN
fnp-2845	232	13	along	along	ADP
fnp-2845	232	14	the	the	DET
fnp-2845	232	15	time	time	NOUN
fnp-2845	232	16	course	course	NOUN
fnp-2845	232	17	of	of	ADP
fnp-2845	232	18	ad	ad	NOUN
fnp-2845	232	19	pathophysiology	pathophysiology	NOUN
fnp-2845	232	20	will	will	AUX
fnp-2845	232	21	be	be	AUX
fnp-2845	232	22	critical	critical	ADJ
fnp-2845	232	23	before	before	SCONJ
fnp-2845	232	24	new	new	ADJ
fnp-2845	232	25	treatments	treatment	NOUN
fnp-2845	232	26	targeting	target	VERB
fnp-2845	232	27	these	these	DET
fnp-2845	232	28	cells	cell	NOUN
fnp-2845	232	29	can	can	AUX
fnp-2845	232	30	be	be	AUX
fnp-2845	232	31	imagined	imagine	VERB
fnp-2845	232	32	.	.	PUNCT
fnp-2845	233	1	given	give	VERB
fnp-2845	233	2	that	that	DET
fnp-2845	233	3	microglia	microglia	NOUN
fnp-2845	233	4	of	of	ADP
fnp-2845	233	5	different	different	ADJ
fnp-2845	233	6	brain	brain	NOUN
fnp-2845	233	7	regions	region	NOUN
fnp-2845	233	8	display	display	VERB
fnp-2845	233	9	different	different	ADJ
fnp-2845	233	10	activation	activation	NOUN
fnp-2845	233	11	states	state	NOUN
fnp-2845	233	12	simultaneously	simultaneously	ADV
fnp-2845	233	13	depending	depend	VERB
fnp-2845	233	14	on	on	ADP
fnp-2845	233	15	the	the	DET
fnp-2845	233	16	graded	grade	VERB
fnp-2845	233	17	extent	extent	NOUN
fnp-2845	233	18	of	of	ADP
fnp-2845	233	19	ad	ad	NOUN
fnp-2845	233	20	-	-	PUNCT
fnp-2845	233	21	type	type	NOUN
fnp-2845	233	22	pathology	pathology	NOUN
fnp-2845	233	23	present	present	NOUN
fnp-2845	233	24	,	,	PUNCT
fnp-2845	233	25	the	the	DET
fnp-2845	233	26	implementation	implementation	NOUN
fnp-2845	233	27	of	of	ADP
fnp-2845	233	28	either	either	CCONJ
fnp-2845	233	29	antior	antior	ADJ
fnp-2845	233	30	pro	pro	ADJ
fnp-2845	233	31	-	-	ADJ
fnp-2845	233	32	inflammatory	inflammatory	ADJ
fnp-2845	233	33	microglia	microglia	NOUN
fnp-2845	233	34	-	-	PUNCT
fnp-2845	233	35	based	base	VERB
fnp-2845	233	36	therapies	therapy	NOUN
fnp-2845	233	37	would	would	AUX
fnp-2845	233	38	presumably	presumably	ADV
fnp-2845	233	39	be	be	AUX
fnp-2845	233	40	beneficial	beneficial	ADJ
fnp-2845	233	41	in	in	ADP
fnp-2845	233	42	one	one	NUM
fnp-2845	233	43	brain	brain	NOUN
fnp-2845	233	44	region	region	NOUN
fnp-2845	233	45	but	but	CCONJ
fnp-2845	233	46	detrimental	detrimental	ADJ
fnp-2845	233	47	in	in	ADP
fnp-2845	233	48	another	another	PRON
fnp-2845	233	49	.	.	PUNCT
fnp-2845	234	1	in	in	ADP
fnp-2845	234	2	future	future	ADJ
fnp-2845	234	3	work	work	NOUN
fnp-2845	234	4	the	the	DET
fnp-2845	234	5	genetic	genetic	ADJ
fnp-2845	234	6	characterisation	characterisation	NOUN
fnp-2845	234	7	of	of	ADP
fnp-2845	234	8	subjects	subject	NOUN
fnp-2845	234	9	investigated	investigate	VERB
fnp-2845	234	10	here	here	ADV
fnp-2845	234	11	may	may	AUX
fnp-2845	234	12	also	also	ADV
fnp-2845	234	13	provide	provide	VERB
fnp-2845	234	14	further	further	ADJ
fnp-2845	234	15	insight	insight	NOUN
fnp-2845	234	16	into	into	ADP
fnp-2845	234	17	how	how	SCONJ
fnp-2845	234	18	genotype	genotype	NOUN
fnp-2845	234	19	affects	affect	VERB
fnp-2845	234	20	individual	individual	ADJ
fnp-2845	234	21	susceptibility	susceptibility	NOUN
fnp-2845	234	22	to	to	PART
fnp-2845	234	23	differential	differential	VERB
fnp-2845	234	24	microglial	microglial	ADJ
fnp-2845	234	25	function	function	NOUN
fnp-2845	234	26	,	,	PUNCT
fnp-2845	234	27	represented	represent	VERB
fnp-2845	234	28	by	by	ADP
fnp-2845	234	29	the	the	DET
fnp-2845	234	30	highly	highly	ADV
fnp-2845	234	31	variable	variable	ADJ
fnp-2845	234	32	clustering	clustering	ADJ
fnp-2845	234	33	response	response	NOUN
fnp-2845	234	34	of	of	ADP
fnp-2845	234	35	microglia	microglia	NOUN
fnp-2845	234	36	in	in	ADP
fnp-2845	234	37	hpcs	hpc	NOUN
fnp-2845	234	38	and	and	CCONJ
fnp-2845	234	39	ad	ad	NOUN
fnp-2845	234	40	cases	case	NOUN
fnp-2845	234	41	in	in	ADP
fnp-2845	234	42	particular	particular	ADJ
fnp-2845	234	43	.	.	PUNCT
fnp-2845	235	1	overall	overall	ADV
fnp-2845	235	2	,	,	PUNCT
fnp-2845	235	3	findings	finding	NOUN
fnp-2845	235	4	from	from	ADP
fnp-2845	235	5	the	the	DET
fnp-2845	235	6	post	post	ADJ
fnp-2845	235	7	-	-	ADJ
fnp-2845	235	8	mortem	mortem	ADJ
fnp-2845	235	9	model	model	NOUN
fnp-2845	235	10	used	use	VERB
fnp-2845	235	11	here	here	ADV
fnp-2845	235	12	suggest	suggest	VERB
fnp-2845	235	13	that	that	SCONJ
fnp-2845	235	14	the	the	DET
fnp-2845	235	15	clustering	clustering	NOUN
fnp-2845	235	16	of	of	ADP
fnp-2845	235	17	activated	activate	VERB
fnp-2845	235	18	microglia	microglia	NOUN
fnp-2845	235	19	occurs	occur	VERB
fnp-2845	235	20	concomitantly	concomitantly	ADV
fnp-2845	235	21	with	with	ADP
fnp-2845	235	22	the	the	DET
fnp-2845	235	23	formation	formation	NOUN
fnp-2845	235	24	of	of	ADP
fnp-2845	235	25	aβ	aβ	DET
fnp-2845	235	26	plaques	plaque	NOUN
fnp-2845	235	27	,	,	PUNCT
fnp-2845	235	28	and	and	CCONJ
fnp-2845	235	29	that	that	SCONJ
fnp-2845	235	30	tau	tau	NOUN
fnp-2845	235	31	-	-	PUNCT
fnp-2845	235	32	related	relate	VERB
fnp-2845	235	33	neuritic	neuritic	ADJ
fnp-2845	235	34	degeneration	degeneration	NOUN
fnp-2845	235	35	follows	follow	VERB
fnp-2845	235	36	these	these	DET
fnp-2845	235	37	changes	change	NOUN
fnp-2845	235	38	along	along	ADP
fnp-2845	235	39	with	with	ADP
fnp-2845	235	40	a	a	DET
fnp-2845	235	41	loss	loss	NOUN
fnp-2845	235	42	of	of	ADP
fnp-2845	235	43	clustering	clustering	NOUN
fnp-2845	235	44	.	.	PUNCT
fnp-2845	236	1	acknowledgements	acknowledgement	NOUN
fnp-2845	236	2	the	the	DET
fnp-2845	236	3	authors	author	NOUN
fnp-2845	236	4	would	would	AUX
fnp-2845	236	5	like	like	VERB
fnp-2845	236	6	to	to	PART
fnp-2845	236	7	thank	thank	VERB
fnp-2845	236	8	the	the	DET
fnp-2845	236	9	donors	donor	NOUN
fnp-2845	236	10	and	and	CCONJ
fnp-2845	236	11	their	their	PRON
fnp-2845	236	12	families	family	NOUN
fnp-2845	236	13	for	for	ADP
fnp-2845	236	14	their	their	PRON
fnp-2845	236	15	kind	kind	ADJ
fnp-2845	236	16	gift	gift	NOUN
fnp-2845	236	17	.	.	PUNCT
fnp-2845	237	1	brain	brain	NOUN
fnp-2845	237	2	tissue	tissue	NOUN
fnp-2845	237	3	was	be	AUX
fnp-2845	237	4	received	receive	VERB
fnp-2845	237	5	from	from	ADP
fnp-2845	237	6	the	the	DET
fnp-2845	237	7	nsw	nsw	PROPN
fnp-2845	237	8	brain	brain	NOUN
fnp-2845	237	9	tissue	tissue	NOUN
fnp-2845	237	10	resource	resource	NOUN
fnp-2845	237	11	centre	centre	NOUN
fnp-2845	237	12	and	and	CCONJ
fnp-2845	237	13	sydney	sydney	PROPN
fnp-2845	237	14	brain	brain	PROPN
fnp-2845	237	15	bank	bank	PROPN
fnp-2845	237	16	.	.	PUNCT
fnp-2845	238	1	these	these	DET
fnp-2845	238	2	brain	brain	NOUN
fnp-2845	238	3	banks	bank	NOUN
fnp-2845	238	4	are	be	AUX
fnp-2845	238	5	supported	support	VERB
fnp-2845	238	6	by	by	ADP
fnp-2845	238	7	the	the	DET
fnp-2845	238	8	nhmrc	nhmrc	NOUN
fnp-2845	238	9	of	of	ADP
fnp-2845	238	10	australia	australia	PROPN
fnp-2845	238	11	,	,	PUNCT
fnp-2845	238	12	the	the	DET
fnp-2845	238	13	university	university	NOUN
fnp-2845	238	14	of	of	ADP
fnp-2845	238	15	new	new	ADJ
fnp-2845	238	16	south	south	PROPN
fnp-2845	238	17	wales	wales	PROPN
fnp-2845	238	18	,	,	PUNCT
fnp-2845	238	19	neuroscience	neuroscience	NOUN
fnp-2845	238	20	research	research	NOUN
fnp-2845	238	21	australia	australia	PROPN
fnp-2845	238	22	,	,	PUNCT
fnp-2845	238	23	and	and	CCONJ
fnp-2845	238	24	the	the	DET
fnp-2845	238	25	national	national	PROPN
fnp-2845	238	26	institute	institute	PROPN
fnp-2845	238	27	of	of	ADP
fnp-2845	238	28	alcohol	alcohol	NOUN
fnp-2845	238	29	abuse	abuse	NOUN
fnp-2845	238	30	and	and	CCONJ
fnp-2845	238	31	alcoholism	alcoholism	NOUN
fnp-2845	238	32	(	(	PUNCT
fnp-2845	238	33	nih	nih	PROPN
fnp-2845	238	34	(	(	PUNCT
fnp-2845	238	35	niaaa	niaaa	PROPN
fnp-2845	238	36	)	)	PUNCT
fnp-2845	238	37	r24aa012725	r24aa012725	NUM
fnp-2845	238	38	)	)	PUNCT
fnp-2845	238	39	.	.	PUNCT
fnp-2845	239	1	the	the	DET
fnp-2845	239	2	authors	author	NOUN
fnp-2845	239	3	also	also	ADV
fnp-2845	239	4	acknowledge	acknowledge	VERB
fnp-2845	239	5	the	the	DET
fnp-2845	239	6	facilities	facility	NOUN
fnp-2845	239	7	used	use	VERB
fnp-2845	239	8	at	at	ADP
fnp-2845	239	9	the	the	DET
fnp-2845	239	10	bosch	bosch	PROPN
fnp-2845	239	11	institute	institute	PROPN
fnp-2845	239	12	and	and	CCONJ
fnp-2845	239	13	microscopy	microscopy	PROPN
fnp-2845	239	14	australia	australia	PROPN
fnp-2845	239	15	at	at	ADP
fnp-2845	239	16	the	the	DET
fnp-2845	239	17	australian	australian	ADJ
fnp-2845	239	18	centre	centre	NOUN
fnp-2845	239	19	for	for	ADP
fnp-2845	239	20	microscopy	microscopy	NOUN
fnp-2845	239	21	&	&	CCONJ
fnp-2845	239	22	microanalysis	microanalysis	PROPN
fnp-2845	239	23	both	both	PRON
fnp-2845	239	24	at	at	ADP
fnp-2845	239	25	the	the	DET
fnp-2845	239	26	university	university	PROPN
fnp-2845	239	27	of	of	ADP
fnp-2845	239	28	sydney	sydney	PROPN
fnp-2845	239	29	.	.	PUNCT
fnp-2845	240	1	data	datum	NOUN
fnp-2845	240	2	availability	availability	NOUN
fnp-2845	240	3	statement	statement	NOUN
fnp-2845	240	4	the	the	DET
fnp-2845	240	5	data	datum	NOUN
fnp-2845	240	6	that	that	PRON
fnp-2845	240	7	support	support	VERB
fnp-2845	240	8	the	the	DET
fnp-2845	240	9	findings	finding	NOUN
fnp-2845	240	10	of	of	ADP
fnp-2845	240	11	this	this	DET
fnp-2845	240	12	study	study	NOUN
fnp-2845	240	13	are	be	AUX
fnp-2845	240	14	available	available	ADJ
fnp-2845	240	15	from	from	ADP
fnp-2845	240	16	the	the	DET
fnp-2845	240	17	corresponding	corresponding	ADJ
fnp-2845	240	18	author	author	NOUN
fnp-2845	240	19	upon	upon	SCONJ
fnp-2845	240	20	reasonable	reasonable	ADJ
fnp-2845	240	21	request	request	NOUN
fnp-2845	240	22	.	.	PUNCT
fnp-2845	241	1	references	reference	NOUN
fnp-2845	241	2	1	1	NUM
fnp-2845	241	3	.	.	PUNCT
fnp-2845	241	4	braak	braak	PROPN
fnp-2845	241	5	e	e	NOUN
fnp-2845	241	6	,	,	PUNCT
fnp-2845	241	7	braak	braak	PROPN
fnp-2845	241	8	h	h	PROPN
fnp-2845	241	9	,	,	PUNCT
fnp-2845	241	10	mandelkow	mandelkow	VERB
fnp-2845	241	11	em	em	PRON
fnp-2845	241	12	.	.	PUNCT
fnp-2845	242	1	a	a	DET
fnp-2845	242	2	sequence	sequence	NOUN
fnp-2845	242	3	of	of	ADP
fnp-2845	242	4	cytoskeleton	cytoskeleton	NOUN
fnp-2845	242	5	changes	change	NOUN
fnp-2845	242	6	related	relate	VERB
fnp-2845	242	7	to	to	ADP
fnp-2845	242	8	the	the	DET
fnp-2845	242	9	formation	formation	NOUN
fnp-2845	242	10	of	of	ADP
fnp-2845	242	11	neurofibrillary	neurofibrillary	ADJ
fnp-2845	242	12	tangles	tangle	NOUN
fnp-2845	242	13	and	and	CCONJ
fnp-2845	242	14	neuropil	neuropil	NOUN
fnp-2845	242	15	threads	thread	NOUN
fnp-2845	242	16	.	.	PUNCT
fnp-2845	243	1	acta	acta	PROPN
fnp-2845	243	2	neuropathol	neuropathol	PROPN
fnp-2845	243	3	.	.	PUNCT
fnp-2845	244	1	1994;87(6):554	1994;87(6):554	NUM
fnp-2845	244	2	-	-	PUNCT
fnp-2845	244	3	67	67	NUM
fnp-2845	244	4	.	.	NOUN
fnp-2845	245	1	2	2	NUM
fnp-2845	245	2	.	.	X
fnp-2845	245	3	perry	perry	PROPN
fnp-2845	245	4	g	g	PROPN
fnp-2845	245	5	,	,	PUNCT
fnp-2845	245	6	kawai	kawai	PROPN
fnp-2845	245	7	m	m	PROPN
fnp-2845	245	8	,	,	PUNCT
fnp-2845	245	9	tabaton	tabaton	PROPN
fnp-2845	245	10	m	m	PROPN
fnp-2845	245	11	,	,	PUNCT
fnp-2845	245	12	onorato	onorato	PROPN
fnp-2845	245	13	m	m	PROPN
fnp-2845	245	14	,	,	PUNCT
fnp-2845	245	15	mulvihill	mulvihill	NOUN
fnp-2845	245	16	p	p	X
fnp-2845	245	17	,	,	PUNCT
fnp-2845	245	18	richey	richey	PROPN
fnp-2845	245	19	p	p	PROPN
fnp-2845	245	20	,	,	PUNCT
fnp-2845	246	1	et	et	PROPN
fnp-2845	246	2	al	al	PROPN
fnp-2845	246	3	.	.	PUNCT
fnp-2845	246	4	neuropil	neuropil	PROPN
fnp-2845	246	5	threads	thread	NOUN
fnp-2845	246	6	of	of	ADP
fnp-2845	246	7	alzheimer	alzheimer	PROPN
fnp-2845	246	8	's	's	PART
fnp-2845	246	9	disease	disease	NOUN
fnp-2845	246	10	show	show	VERB
fnp-2845	246	11	a	a	DET
fnp-2845	246	12	marked	mark	VERB
fnp-2845	246	13	alteration	alteration	NOUN
fnp-2845	246	14	of	of	ADP
fnp-2845	246	15	the	the	DET
fnp-2845	246	16	normal	normal	ADJ
fnp-2845	246	17	cytoskeleton	cytoskeleton	NOUN
fnp-2845	246	18	.	.	PUNCT
fnp-2845	247	1	j	j	PROPN
fnp-2845	247	2	neurosci	neurosci	PROPN
fnp-2845	247	3	.	.	PUNCT
fnp-2845	248	1	1991;11(6):1748	1991;11(6):1748	NUM
fnp-2845	248	2	-	-	SYM
fnp-2845	248	3	55	55	NUM
fnp-2845	248	4	.	.	PUNCT
fnp-2845	249	1	3	3	X
fnp-2845	249	2	.	.	X
fnp-2845	249	3	barghorn	barghorn	PROPN
fnp-2845	249	4	s	s	PROPN
fnp-2845	249	5	,	,	PUNCT
fnp-2845	249	6	davies	davy	NOUN
fnp-2845	249	7	p	p	X
fnp-2845	249	8	,	,	PUNCT
fnp-2845	249	9	mandelkow	mandelkow	PROPN
fnp-2845	249	10	e.	e.	PROPN
fnp-2845	249	11	tau	tau	PROPN
fnp-2845	249	12	paired	pair	VERB
fnp-2845	249	13	helical	helical	ADJ
fnp-2845	249	14	filaments	filament	NOUN
fnp-2845	249	15	from	from	ADP
fnp-2845	249	16	alzheimer	alzheimer	PROPN
fnp-2845	249	17	's	's	PART
fnp-2845	249	18	disease	disease	NOUN
fnp-2845	249	19	brain	brain	NOUN
fnp-2845	249	20	and	and	CCONJ
fnp-2845	249	21	assembled	assemble	VERB
fnp-2845	249	22	in	in	ADP
fnp-2845	249	23	vitro	vitro	X
fnp-2845	249	24	are	be	AUX
fnp-2845	249	25	based	base	VERB
fnp-2845	249	26	on	on	ADP
fnp-2845	249	27	beta	beta	NOUN
fnp-2845	249	28	-	-	PUNCT
fnp-2845	249	29	structure	structure	NOUN
fnp-2845	249	30	in	in	ADP
fnp-2845	249	31	the	the	DET
fnp-2845	249	32	core	core	NOUN
fnp-2845	249	33	domain	domain	NOUN
fnp-2845	249	34	.	.	PUNCT
fnp-2845	250	1	biochemistry	biochemistry	NOUN
fnp-2845	250	2	.	.	PUNCT
fnp-2845	251	1	2004;43(6):1694	2004;43(6):1694	NUM
fnp-2845	251	2	-	-	SYM
fnp-2845	251	3	703	703	NUM
fnp-2845	251	4	.	.	NOUN
fnp-2845	252	1	4	4	NUM
fnp-2845	252	2	.	.	X
fnp-2845	252	3	fitzpatrick	fitzpatrick	PROPN
fnp-2845	252	4	awp	awp	PROPN
fnp-2845	252	5	,	,	PUNCT
fnp-2845	252	6	falcon	falcon	PROPN
fnp-2845	252	7	b	b	PROPN
fnp-2845	252	8	,	,	PUNCT
fnp-2845	252	9	he	he	PRON
fnp-2845	252	10	s	s	PROPN
fnp-2845	252	11	,	,	PUNCT
fnp-2845	252	12	murzin	murzin	PROPN
fnp-2845	252	13	ag	ag	PROPN
fnp-2845	252	14	,	,	PUNCT
fnp-2845	252	15	murshudov	murshudov	PROPN
fnp-2845	252	16	g	g	PROPN
fnp-2845	252	17	,	,	PUNCT
fnp-2845	252	18	garringer	garringer	PROPN
fnp-2845	252	19	hj	hj	PROPN
fnp-2845	252	20	,	,	PUNCT
fnp-2845	252	21	et	et	PROPN
fnp-2845	252	22	al	al	PROPN
fnp-2845	252	23	.	.	PUNCT
fnp-2845	253	1	cryo	cryo	PROPN
fnp-2845	253	2	-	-	PUNCT
fnp-2845	253	3	em	em	PRON
fnp-2845	253	4	structures	structure	NOUN
fnp-2845	253	5	of	of	ADP
fnp-2845	253	6	tau	tau	PROPN
fnp-2845	253	7	filaments	filament	NOUN
fnp-2845	253	8	from	from	ADP
fnp-2845	253	9	alzheimer	alzheimer	PROPN
fnp-2845	253	10	's	's	PART
fnp-2845	253	11	disease	disease	NOUN
fnp-2845	253	12	.	.	PUNCT
fnp-2845	254	1	nature	nature	NOUN
fnp-2845	254	2	.	.	PUNCT
fnp-2845	255	1	2017;547(7662):185	2017;547(7662):185	NUM
fnp-2845	255	2	-	-	SYM
fnp-2845	255	3	90	90	NUM
fnp-2845	255	4	.	.	PUNCT
fnp-2845	256	1	5	5	NUM
fnp-2845	256	2	.	.	X
fnp-2845	256	3	braak	braak	PROPN
fnp-2845	256	4	h	h	PROPN
fnp-2845	256	5	,	,	PUNCT
fnp-2845	256	6	braak	braak	PROPN
fnp-2845	256	7	e.	e.	PROPN
fnp-2845	256	8	neuropathological	neuropathological	PROPN
fnp-2845	256	9	stageing	stage	VERB
fnp-2845	256	10	of	of	ADP
fnp-2845	256	11	alzheimer	alzheimer	NOUN
fnp-2845	256	12	-	-	PUNCT
fnp-2845	256	13	related	relate	VERB
fnp-2845	256	14	changes	change	NOUN
fnp-2845	256	15	.	.	PUNCT
fnp-2845	257	1	acta	acta	PROPN
fnp-2845	257	2	neuropathol	neuropathol	PROPN
fnp-2845	257	3	.	.	PUNCT
fnp-2845	258	1	1991;82(4):239	1991;82(4):239	NUM
fnp-2845	258	2	-	-	SYM
fnp-2845	258	3	59	59	NUM
fnp-2845	258	4	.	.	NOUN
fnp-2845	258	5	6	6	NUM
fnp-2845	258	6	.	.	NOUN
fnp-2845	258	7	franzmeier	franzmeier	PROPN
fnp-2845	258	8	n	n	CCONJ
fnp-2845	258	9	,	,	PUNCT
fnp-2845	258	10	neitzel	neitzel	PROPN
fnp-2845	258	11	j	j	PROPN
fnp-2845	258	12	,	,	PUNCT
fnp-2845	258	13	rubinski	rubinski	VERB
fnp-2845	258	14	a	a	PROPN
fnp-2845	258	15	,	,	PUNCT
fnp-2845	258	16	smith	smith	PROPN
fnp-2845	258	17	r	r	PROPN
fnp-2845	258	18	,	,	PUNCT
fnp-2845	258	19	strandberg	strandberg	PROPN
fnp-2845	258	20	o	o	PROPN
fnp-2845	258	21	,	,	PUNCT
fnp-2845	258	22	ossenkoppele	ossenkoppele	PROPN
fnp-2845	258	23	r	r	PROPN
fnp-2845	258	24	,	,	PUNCT
fnp-2845	258	25	et	et	PROPN
fnp-2845	259	1	al	al	PROPN
fnp-2845	259	2	.	.	PROPN
fnp-2845	259	3	functional	functional	ADJ
fnp-2845	259	4	brain	brain	NOUN
fnp-2845	259	5	architecture	architecture	NOUN
fnp-2845	259	6	is	be	AUX
fnp-2845	259	7	associated	associate	VERB
fnp-2845	259	8	with	with	ADP
fnp-2845	259	9	the	the	DET
fnp-2845	259	10	rate	rate	NOUN
fnp-2845	259	11	of	of	ADP
fnp-2845	259	12	tau	tau	PROPN
fnp-2845	259	13	accumulation	accumulation	NOUN
fnp-2845	259	14	in	in	ADP
fnp-2845	259	15	alzheimer	alzheimer	PROPN
fnp-2845	259	16	's	's	PART
fnp-2845	259	17	disease	disease	NOUN
fnp-2845	259	18	.	.	PUNCT
fnp-2845	260	1	nat	nat	PROPN
fnp-2845	260	2	commun	commun	PROPN
fnp-2845	260	3	.	.	PUNCT
fnp-2845	261	1	2020;11(1):347	2020;11(1):347	NOUN
fnp-2845	261	2	.	.	PUNCT
fnp-2845	262	1	7	7	X
fnp-2845	262	2	.	.	X
fnp-2845	262	3	nelson	nelson	PROPN
fnp-2845	262	4	pt	pt	PROPN
fnp-2845	262	5	,	,	PUNCT
fnp-2845	262	6	alafuzoff	alafuzoff	NOUN
fnp-2845	263	1	i	i	PRON
fnp-2845	263	2	,	,	PUNCT
fnp-2845	263	3	bigio	bigio	NOUN
fnp-2845	263	4	eh	eh	INTJ
fnp-2845	263	5	,	,	PUNCT
fnp-2845	263	6	bouras	boura	NOUN
fnp-2845	263	7	c	c	NOUN
fnp-2845	263	8	,	,	PUNCT
fnp-2845	263	9	braak	braak	PROPN
fnp-2845	263	10	h	h	PROPN
fnp-2845	263	11	,	,	PUNCT
fnp-2845	263	12	cairns	cairns	PROPN
fnp-2845	263	13	nj	nj	PROPN
fnp-2845	263	14	,	,	PUNCT
fnp-2845	263	15	et	et	PROPN
fnp-2845	263	16	al	al	PROPN
fnp-2845	263	17	.	.	PUNCT
fnp-2845	263	18	correlation	correlation	NOUN
fnp-2845	263	19	of	of	ADP
fnp-2845	263	20	alzheimer	alzheimer	PROPN
fnp-2845	263	21	disease	disease	PROPN
fnp-2845	263	22	neuropathologic	neuropathologic	NOUN
fnp-2845	263	23	changes	change	NOUN
fnp-2845	263	24	with	with	ADP
fnp-2845	263	25	cognitive	cognitive	ADJ
fnp-2845	263	26	status	status	NOUN
fnp-2845	263	27	:	:	PUNCT
fnp-2845	263	28	a	a	DET
fnp-2845	263	29	review	review	NOUN
fnp-2845	263	30	of	of	ADP
fnp-2845	263	31	the	the	DET
fnp-2845	263	32	literature	literature	NOUN
fnp-2845	263	33	.	.	PUNCT
fnp-2845	264	1	j	j	PROPN
fnp-2845	264	2	neuropathol	neuropathol	PROPN
fnp-2845	264	3	exp	exp	PROPN
fnp-2845	264	4	neurol	neurol	NOUN
fnp-2845	264	5	.	.	PUNCT
fnp-2845	265	1	2012;71	2012;71	NUM
fnp-2845	265	2	.	.	NOUN
fnp-2845	265	3	8	8	NUM
fnp-2845	265	4	.	.	X
fnp-2845	265	5	arriagada	arriagada	PROPN
fnp-2845	265	6	pv	pv	PROPN
fnp-2845	265	7	,	,	PUNCT
fnp-2845	265	8	growdon	growdon	VERB
fnp-2845	265	9	jh	jh	PROPN
fnp-2845	265	10	,	,	PUNCT
fnp-2845	265	11	hedley	hedley	PROPN
fnp-2845	265	12	-	-	PUNCT
fnp-2845	265	13	whyte	whyte	PROPN
fnp-2845	265	14	et	et	PROPN
fnp-2845	265	15	,	,	PUNCT
fnp-2845	265	16	hyman	hyman	PROPN
fnp-2845	265	17	bt	bt	PROPN
fnp-2845	265	18	.	.	PROPN
fnp-2845	265	19	neurofibrillary	neurofibrillary	ADJ
fnp-2845	265	20	tangles	tangle	NOUN
fnp-2845	265	21	but	but	CCONJ
fnp-2845	265	22	not	not	PART
fnp-2845	265	23	senile	senile	ADJ
fnp-2845	265	24	plaques	plaque	NOUN
fnp-2845	265	25	parallel	parallel	ADJ
fnp-2845	265	26	duration	duration	NOUN
fnp-2845	265	27	and	and	CCONJ
fnp-2845	265	28	severity	severity	NOUN
fnp-2845	265	29	of	of	ADP
fnp-2845	265	30	alzheimer	alzheimer	PROPN
fnp-2845	265	31	's	's	PART
fnp-2845	265	32	disease	disease	NOUN
fnp-2845	265	33	.	.	PUNCT
fnp-2845	266	1	neurology	neurology	NOUN
fnp-2845	266	2	.	.	PUNCT
fnp-2845	267	1	1992;42(3	1992;42(3	NUM
fnp-2845	267	2	pt	pt	NOUN
fnp-2845	267	3	1):631	1):631	NUM
fnp-2845	267	4	-	-	PUNCT
fnp-2845	267	5	9	9	NUM
fnp-2845	267	6	.	.	NOUN
fnp-2845	267	7	9	9	NUM
fnp-2845	267	8	.	.	X
fnp-2845	267	9	thal	thal	PROPN
fnp-2845	267	10	dr	dr	PROPN
fnp-2845	267	11	,	,	PUNCT
fnp-2845	267	12	rub	rub	PROPN
fnp-2845	267	13	u	u	NOUN
fnp-2845	267	14	,	,	PUNCT
fnp-2845	267	15	orantes	orantes	PROPN
fnp-2845	267	16	m	m	PROPN
fnp-2845	267	17	,	,	PUNCT
fnp-2845	267	18	braak	braak	PROPN
fnp-2845	267	19	h.	h.	PROPN
fnp-2845	267	20	phases	phase	NOUN
fnp-2845	267	21	of	of	ADP
fnp-2845	267	22	a	a	DET
fnp-2845	267	23	beta	beta	NOUN
fnp-2845	267	24	-	-	PUNCT
fnp-2845	267	25	deposition	deposition	NOUN
fnp-2845	267	26	in	in	ADP
fnp-2845	267	27	the	the	DET
fnp-2845	267	28	human	human	ADJ
fnp-2845	267	29	brain	brain	NOUN
fnp-2845	267	30	and	and	CCONJ
fnp-2845	267	31	its	its	PRON
fnp-2845	267	32	relevance	relevance	NOUN
fnp-2845	267	33	for	for	ADP
fnp-2845	267	34	the	the	DET
fnp-2845	267	35	development	development	NOUN
fnp-2845	267	36	of	of	ADP
fnp-2845	267	37	ad	ad	NOUN
fnp-2845	267	38	.	.	PUNCT
fnp-2845	267	39	neurology	neurology	NOUN
fnp-2845	267	40	.	.	PUNCT
fnp-2845	268	1	2002;58(12):1791	2002;58(12):1791	NUM
fnp-2845	268	2	-	-	SYM
fnp-2845	268	3	800	800	NUM
fnp-2845	268	4	.	.	NOUN
fnp-2845	268	5	10	10	NUM
fnp-2845	268	6	.	.	X
fnp-2845	268	7	serrano	serrano	PROPN
fnp-2845	268	8	-	-	PUNCT
fnp-2845	268	9	pozo	pozo	PROPN
fnp-2845	268	10	a	a	X
fnp-2845	268	11	,	,	PUNCT
fnp-2845	268	12	mielke	mielke	ADJ
fnp-2845	268	13	ml	ml	NOUN
fnp-2845	268	14	,	,	PUNCT
fnp-2845	268	15	gomez	gomez	PROPN
fnp-2845	268	16	-	-	PUNCT
fnp-2845	268	17	isla	isla	PROPN
fnp-2845	268	18	t	t	PROPN
fnp-2845	268	19	,	,	PUNCT
fnp-2845	268	20	betensky	betensky	PROPN
fnp-2845	268	21	ra	ra	PROPN
fnp-2845	268	22	,	,	PUNCT
fnp-2845	268	23	growdon	growdon	VERB
fnp-2845	268	24	jh	jh	PROPN
fnp-2845	268	25	,	,	PUNCT
fnp-2845	268	26	frosch	frosch	PROPN
fnp-2845	268	27	mp	mp	PROPN
fnp-2845	268	28	,	,	PUNCT
fnp-2845	268	29	et	et	PROPN
fnp-2845	268	30	al	al	PROPN
fnp-2845	268	31	.	.	PROPN
fnp-2845	268	32	reactive	reactive	ADJ
fnp-2845	268	33	glia	glia	NOUN
fnp-2845	268	34	not	not	PART
fnp-2845	268	35	only	only	ADV
fnp-2845	268	36	associates	associate	NOUN
fnp-2845	268	37	with	with	ADP
fnp-2845	268	38	plaques	plaque	NOUN
fnp-2845	268	39	but	but	CCONJ
fnp-2845	268	40	also	also	ADV
fnp-2845	268	41	parallels	parallel	VERB
fnp-2845	268	42	tangles	tangle	NOUN
fnp-2845	268	43	in	in	ADP
fnp-2845	268	44	alzheimer	alzheimer	PROPN
fnp-2845	268	45	's	's	PART
fnp-2845	268	46	disease	disease	NOUN
fnp-2845	268	47	.	.	PUNCT
fnp-2845	269	1	am	be	AUX
fnp-2845	269	2	j	j	PROPN
fnp-2845	269	3	pathol	pathol	NOUN
fnp-2845	269	4	.	.	PUNCT
fnp-2845	270	1	2011;179(3):1373	2011;179(3):1373	NUM
fnp-2845	270	2	-	-	SYM
fnp-2845	270	3	84	84	NUM
fnp-2845	270	4	.	.	PUNCT
fnp-2845	271	1	11	11	NUM
fnp-2845	271	2	.	.	PUNCT
fnp-2845	271	3	mirra	mirra	PROPN
fnp-2845	271	4	ss	ss	PROPN
fnp-2845	271	5	,	,	PUNCT
fnp-2845	271	6	heyman	heyman	PROPN
fnp-2845	271	7	a	a	PROPN
fnp-2845	271	8	,	,	PUNCT
fnp-2845	271	9	mckeel	mckeel	NOUN
fnp-2845	271	10	d	d	PROPN
fnp-2845	271	11	,	,	PUNCT
fnp-2845	271	12	sumi	sumi	NOUN
fnp-2845	271	13	sm	sm	PROPN
fnp-2845	271	14	,	,	PUNCT
fnp-2845	271	15	crain	crain	NOUN
fnp-2845	271	16	bj	bj	PROPN
fnp-2845	271	17	,	,	PUNCT
fnp-2845	271	18	brownlee	brownlee	PROPN
fnp-2845	271	19	lm	lm	PROPN
fnp-2845	271	20	,	,	PUNCT
fnp-2845	271	21	et	et	PROPN
fnp-2845	271	22	al	al	PROPN
fnp-2845	271	23	.	.	PUNCT
fnp-2845	272	1	the	the	DET
fnp-2845	272	2	consortium	consortium	NOUN
fnp-2845	272	3	to	to	PART
fnp-2845	272	4	establish	establish	VERB
fnp-2845	272	5	a	a	DET
fnp-2845	272	6	registry	registry	NOUN
fnp-2845	272	7	for	for	ADP
fnp-2845	272	8	alzheimer	alzheimer	PROPN
fnp-2845	272	9	's	's	PART
fnp-2845	272	10	disease	disease	NOUN
fnp-2845	272	11	(	(	PUNCT
fnp-2845	272	12	cerad	cerad	PROPN
fnp-2845	272	13	)	)	PUNCT
fnp-2845	272	14	.	.	PUNCT
fnp-2845	273	1	part	part	PROPN
fnp-2845	273	2	ii	ii	PROPN
fnp-2845	273	3	.	.	PUNCT
fnp-2845	274	1	standardization	standardization	NOUN
fnp-2845	274	2	of	of	ADP
fnp-2845	274	3	the	the	DET
fnp-2845	274	4	neuropathologic	neuropathologic	ADJ
fnp-2845	274	5	assessment	assessment	NOUN
fnp-2845	274	6	of	of	ADP
fnp-2845	274	7	alzheimer	alzheimer	PROPN
fnp-2845	274	8	's	's	PART
fnp-2845	274	9	disease	disease	NOUN
fnp-2845	274	10	.	.	PUNCT
fnp-2845	275	1	neurology	neurology	NOUN
fnp-2845	275	2	.	.	PUNCT
fnp-2845	276	1	1991;41(4):479	1991;41(4):479	PROPN
fnp-2845	276	2	-	-	SYM
fnp-2845	276	3	86	86	NUM
fnp-2845	276	4	.	.	PUNCT
fnp-2845	276	5	12	12	NUM
fnp-2845	276	6	.	.	PUNCT
fnp-2845	277	1	dickson	dickson	PROPN
fnp-2845	277	2	tc	tc	PROPN
fnp-2845	277	3	,	,	PUNCT
fnp-2845	277	4	vickers	vickers	PROPN
fnp-2845	277	5	jc	jc	PROPN
fnp-2845	277	6	.	.	PUNCT
fnp-2845	278	1	the	the	DET
fnp-2845	278	2	morphological	morphological	ADJ
fnp-2845	278	3	phenotype	phenotype	NOUN
fnp-2845	278	4	of	of	ADP
fnp-2845	278	5	beta	beta	NOUN
fnp-2845	278	6	-	-	PUNCT
fnp-2845	278	7	amyloid	amyloid	NOUN
fnp-2845	278	8	plaques	plaque	NOUN
fnp-2845	278	9	and	and	CCONJ
fnp-2845	278	10	associated	associate	VERB
fnp-2845	278	11	neuritic	neuritic	ADJ
fnp-2845	278	12	changes	change	NOUN
fnp-2845	278	13	in	in	ADP
fnp-2845	278	14	alzheimer	alzheimer	PROPN
fnp-2845	278	15	's	's	PART
fnp-2845	278	16	disease	disease	NOUN
fnp-2845	278	17	.	.	PUNCT
fnp-2845	279	1	neuroscience	neuroscience	NOUN
fnp-2845	279	2	.	.	PUNCT
fnp-2845	280	1	2001;105(1):99	2001;105(1):99	NUM
fnp-2845	280	2	-	-	SYM
fnp-2845	280	3	107	107	NUM
fnp-2845	280	4	.	.	PUNCT
fnp-2845	281	1	13	13	NUM
fnp-2845	281	2	.	.	PUNCT
fnp-2845	282	1	yasuhara	yasuhara	PROPN
fnp-2845	282	2	o	o	NOUN
fnp-2845	282	3	,	,	PUNCT
fnp-2845	282	4	kawamata	kawamata	PROPN
fnp-2845	282	5	t	t	PROPN
fnp-2845	282	6	,	,	PUNCT
fnp-2845	282	7	aimi	aimi	PROPN
fnp-2845	282	8	y	y	PROPN
fnp-2845	282	9	,	,	PUNCT
fnp-2845	282	10	mcgeer	mcgeer	PROPN
fnp-2845	282	11	eg	eg	PROPN
fnp-2845	282	12	,	,	PUNCT
fnp-2845	282	13	mcgeer	mcgeer	PROPN
fnp-2845	282	14	pl	pl	PROPN
fnp-2845	282	15	.	.	PROPN
fnp-2845	282	16	two	two	NUM
fnp-2845	282	17	types	type	NOUN
fnp-2845	282	18	of	of	ADP
fnp-2845	282	19	dystrophic	dystrophic	ADJ
fnp-2845	282	20	neurites	neurite	NOUN
fnp-2845	282	21	in	in	ADP
fnp-2845	282	22	senile	senile	ADJ
fnp-2845	282	23	plaques	plaque	NOUN
fnp-2845	282	24	of	of	ADP
fnp-2845	282	25	alzheimer	alzheimer	PROPN
fnp-2845	282	26	disease	disease	NOUN
fnp-2845	282	27	and	and	CCONJ
fnp-2845	282	28	elderly	elderly	ADJ
fnp-2845	282	29	non	non	ADJ
fnp-2845	282	30	-	-	ADJ
fnp-2845	282	31	demented	demented	ADJ
fnp-2845	282	32	cases	case	NOUN
fnp-2845	282	33	.	.	PUNCT
fnp-2845	283	1	neurosci	neurosci	PROPN
fnp-2845	283	2	lett	lett	PROPN
fnp-2845	283	3	.	.	PUNCT
fnp-2845	284	1	1994;171(1	1994;171(1	PROPN
fnp-2845	284	2	-	-	PUNCT
fnp-2845	284	3	2):73	2):73	NUM
fnp-2845	284	4	-	-	PUNCT
fnp-2845	284	5	6	6	NUM
fnp-2845	284	6	.	.	NOUN
fnp-2845	284	7	14	14	NUM
fnp-2845	284	8	.	.	PUNCT
fnp-2845	285	1	oide	oide	PROPN
fnp-2845	285	2	t	t	PROPN
fnp-2845	285	3	,	,	PUNCT
fnp-2845	285	4	kinoshita	kinoshita	PROPN
fnp-2845	285	5	t	t	PROPN
fnp-2845	285	6	,	,	PUNCT
fnp-2845	285	7	arima	arima	PROPN
fnp-2845	285	8	k.	k.	PROPN
fnp-2845	285	9	regression	regression	PROPN
fnp-2845	285	10	stage	stage	NOUN
fnp-2845	285	11	senile	senile	ADJ
fnp-2845	285	12	plaques	plaque	NOUN
fnp-2845	285	13	in	in	ADP
fnp-2845	285	14	the	the	DET
fnp-2845	285	15	natural	natural	ADJ
fnp-2845	285	16	course	course	NOUN
fnp-2845	285	17	of	of	ADP
fnp-2845	285	18	alzheimer	alzheimer	PROPN
fnp-2845	285	19	's	's	PART
fnp-2845	285	20	disease	disease	NOUN
fnp-2845	285	21	.	.	PUNCT
fnp-2845	286	1	neuropathol	neuropathol	PROPN
fnp-2845	286	2	appl	appl	PROPN
fnp-2845	286	3	neurobiol	neurobiol	PROPN
fnp-2845	286	4	.	.	PUNCT
fnp-2845	287	1	2006;32(5):539	2006;32(5):539	NUM
fnp-2845	287	2	-	-	SYM
fnp-2845	287	3	56	56	NUM
fnp-2845	287	4	.	.	NOUN
fnp-2845	287	5	15	15	NUM
fnp-2845	287	6	.	.	PUNCT
fnp-2845	287	7	yu	yu	PROPN
fnp-2845	288	1	l	l	NOUN
fnp-2845	288	2	,	,	PUNCT
fnp-2845	288	3	petyuk	petyuk	PROPN
fnp-2845	288	4	va	va	PROPN
fnp-2845	288	5	,	,	PUNCT
fnp-2845	288	6	tasaki	tasaki	PROPN
fnp-2845	288	7	s	s	PROPN
fnp-2845	288	8	,	,	PUNCT
fnp-2845	288	9	boyle	boyle	PROPN
fnp-2845	288	10	pa	pa	PROPN
fnp-2845	288	11	,	,	PUNCT
fnp-2845	288	12	gaiteri	gaiteri	ADJ
fnp-2845	288	13	c	c	PROPN
fnp-2845	288	14	,	,	PUNCT
fnp-2845	288	15	schneider	schneider	PROPN
fnp-2845	288	16	ja	ja	PROPN
fnp-2845	288	17	,	,	PUNCT
fnp-2845	288	18	et	et	PROPN
fnp-2845	288	19	al	al	PROPN
fnp-2845	288	20	.	.	PROPN
fnp-2845	288	21	association	association	PROPN
fnp-2845	288	22	of	of	ADP
fnp-2845	288	23	cortical	cortical	ADJ
fnp-2845	288	24	beta	beta	NOUN
fnp-2845	288	25	-	-	PUNCT
fnp-2845	288	26	amyloid	amyloid	NOUN
fnp-2845	288	27	protein	protein	NOUN
fnp-2845	288	28	in	in	ADP
fnp-2845	288	29	the	the	DET
fnp-2845	288	30	absence	absence	NOUN
fnp-2845	288	31	of	of	ADP
fnp-2845	288	32	insoluble	insoluble	ADJ
fnp-2845	288	33	deposits	deposit	NOUN
fnp-2845	288	34	with	with	ADP
fnp-2845	288	35	alzheimer	alzheimer	PROPN
fnp-2845	288	36	disease	disease	PROPN
fnp-2845	288	37	.	.	PUNCT
fnp-2845	289	1	jama	jama	PROPN
fnp-2845	289	2	neurol	neurol	PROPN
fnp-2845	289	3	.	.	PUNCT
fnp-2845	290	1	2019	2019	NUM
fnp-2845	290	2	.	.	PUNCT
fnp-2845	291	1	16	16	NUM
fnp-2845	291	2	.	.	PUNCT
fnp-2845	292	1	lesne	lesne	PROPN
fnp-2845	292	2	se	se	PROPN
fnp-2845	292	3	,	,	PUNCT
fnp-2845	292	4	sherman	sherman	PROPN
fnp-2845	292	5	ma	ma	PROPN
fnp-2845	292	6	,	,	PUNCT
fnp-2845	292	7	grant	grant	PROPN
fnp-2845	292	8	m	m	PROPN
fnp-2845	292	9	,	,	PUNCT
fnp-2845	292	10	kuskowski	kuskowski	PROPN
fnp-2845	292	11	m	m	PROPN
fnp-2845	292	12	,	,	PUNCT
fnp-2845	292	13	schneider	schneider	PROPN
fnp-2845	292	14	ja	ja	PROPN
fnp-2845	292	15	,	,	PUNCT
fnp-2845	292	16	bennett	bennett	PROPN
fnp-2845	292	17	da	da	PROPN
fnp-2845	292	18	,	,	PUNCT
fnp-2845	292	19	et	et	PROPN
fnp-2845	292	20	al	al	PROPN
fnp-2845	292	21	.	.	PROPN
fnp-2845	292	22	brain	brain	NOUN
fnp-2845	292	23	amyloid	amyloid	NOUN
fnp-2845	292	24	-	-	PUNCT
fnp-2845	292	25	beta	beta	NOUN
fnp-2845	292	26	oligomers	oligomer	NOUN
fnp-2845	292	27	in	in	ADP
fnp-2845	292	28	ageing	age	VERB
fnp-2845	292	29	and	and	CCONJ
fnp-2845	292	30	alzheimer	alzheimer	NOUN
fnp-2845	292	31	's	's	PART
fnp-2845	292	32	disease	disease	NOUN
fnp-2845	292	33	.	.	PUNCT
fnp-2845	293	1	brain	brain	NOUN
fnp-2845	293	2	.	.	PUNCT
fnp-2845	294	1	2013;136(pt	2013;136(pt	PROPN
fnp-2845	294	2	5):1383	5):1383	PROPN
fnp-2845	294	3	-	-	PUNCT
fnp-2845	294	4	98	98	NUM
fnp-2845	294	5	.	.	PUNCT
fnp-2845	294	6	17	17	NUM
fnp-2845	294	7	.	.	PUNCT
fnp-2845	294	8	lue	lue	PROPN
fnp-2845	294	9	lf	lf	PROPN
fnp-2845	294	10	,	,	PUNCT
fnp-2845	294	11	kuo	kuo	PROPN
fnp-2845	294	12	ym	ym	PROPN
fnp-2845	294	13	,	,	PUNCT
fnp-2845	294	14	roher	roher	ADV
fnp-2845	294	15	ae	ae	PROPN
fnp-2845	294	16	,	,	PUNCT
fnp-2845	294	17	brachova	brachova	PROPN
fnp-2845	294	18	l	l	NOUN
fnp-2845	294	19	,	,	PUNCT
fnp-2845	294	20	shen	shen	PROPN
fnp-2845	294	21	y	y	PROPN
fnp-2845	294	22	,	,	PUNCT
fnp-2845	294	23	sue	sue	PROPN
fnp-2845	294	24	l	l	PROPN
fnp-2845	294	25	,	,	PUNCT
fnp-2845	294	26	et	et	PROPN
fnp-2845	294	27	al	al	PROPN
fnp-2845	294	28	.	.	PROPN
fnp-2845	295	1	soluble	soluble	ADJ
fnp-2845	295	2	amyloid	amyloid	NOUN
fnp-2845	295	3	beta	beta	NOUN
fnp-2845	295	4	peptide	peptide	NOUN
fnp-2845	295	5	concentration	concentration	NOUN
fnp-2845	295	6	as	as	ADP
fnp-2845	295	7	a	a	DET
fnp-2845	295	8	predictor	predictor	NOUN
fnp-2845	295	9	of	of	ADP
fnp-2845	295	10	synaptic	synaptic	ADJ
fnp-2845	295	11	change	change	NOUN
fnp-2845	295	12	in	in	ADP
fnp-2845	295	13	alzheimer	alzheimer	PROPN
fnp-2845	295	14	's	's	PART
fnp-2845	295	15	disease	disease	NOUN
fnp-2845	295	16	.	.	PUNCT
fnp-2845	296	1	am	be	AUX
fnp-2845	296	2	j	j	PROPN
fnp-2845	296	3	pathol	pathol	NOUN
fnp-2845	296	4	.	.	PUNCT
fnp-2845	297	1	1999;155(3):853	1999;155(3):853	NUM
fnp-2845	297	2	-	-	SYM
fnp-2845	297	3	62	62	NUM
fnp-2845	297	4	.	.	PUNCT
fnp-2845	298	1	18	18	NUM
fnp-2845	298	2	.	.	X
fnp-2845	298	3	mclean	mclean	PROPN
fnp-2845	298	4	ca	ca	PROPN
fnp-2845	298	5	,	,	PUNCT
fnp-2845	298	6	cherny	cherny	PROPN
fnp-2845	298	7	ra	ra	PROPN
fnp-2845	298	8	,	,	PUNCT
fnp-2845	298	9	fraser	fraser	PROPN
fnp-2845	298	10	fw	fw	ADJ
fnp-2845	298	11	,	,	PUNCT
fnp-2845	298	12	fuller	full	ADJ
fnp-2845	298	13	sj	sj	PROPN
fnp-2845	298	14	,	,	PUNCT
fnp-2845	298	15	smith	smith	PROPN
fnp-2845	298	16	mj	mj	PROPN
fnp-2845	298	17	,	,	PUNCT
fnp-2845	298	18	beyreuther	beyreuther	PROPN
fnp-2845	298	19	k	k	PROPN
fnp-2845	298	20	,	,	PUNCT
fnp-2845	298	21	et	et	PROPN
fnp-2845	298	22	al	al	PROPN
fnp-2845	298	23	.	.	PROPN
fnp-2845	298	24	soluble	soluble	ADJ
fnp-2845	298	25	pool	pool	NOUN
fnp-2845	298	26	of	of	ADP
fnp-2845	298	27	abeta	abeta	PROPN
fnp-2845	298	28	amyloid	amyloid	NOUN
fnp-2845	298	29	as	as	ADP
fnp-2845	298	30	a	a	DET
fnp-2845	298	31	determinant	determinant	NOUN
fnp-2845	298	32	of	of	ADP
fnp-2845	298	33	severity	severity	NOUN
fnp-2845	298	34	of	of	ADP
fnp-2845	298	35	neurodegeneration	neurodegeneration	NOUN
fnp-2845	298	36	in	in	ADP
fnp-2845	298	37	alzheimer	alzheimer	PROPN
fnp-2845	298	38	's	's	PART
fnp-2845	298	39	disease	disease	NOUN
fnp-2845	298	40	.	.	PUNCT
fnp-2845	299	1	ann	ann	PROPN
fnp-2845	299	2	neurol	neurol	PROPN
fnp-2845	299	3	.	.	PUNCT
fnp-2845	300	1	1999;46(6):860	1999;46(6):860	PROPN
fnp-2845	300	2	-	-	PUNCT
fnp-2845	300	3	6	6	NUM
fnp-2845	300	4	.	.	NOUN
fnp-2845	300	5	19	19	NUM
fnp-2845	300	6	.	.	PUNCT
fnp-2845	301	1	selkoe	selkoe	PROPN
fnp-2845	301	2	dj	dj	NOUN
fnp-2845	301	3	,	,	PUNCT
fnp-2845	301	4	hardy	hardy	ADJ
fnp-2845	301	5	j.	j.	PROPN
fnp-2845	301	6	the	the	DET
fnp-2845	301	7	amyloid	amyloid	NOUN
fnp-2845	301	8	hypothesis	hypothesis	NOUN
fnp-2845	301	9	of	of	ADP
fnp-2845	301	10	alzheimer	alzheimer	PROPN
fnp-2845	301	11	's	's	PART
fnp-2845	301	12	disease	disease	NOUN
fnp-2845	301	13	at	at	ADP
fnp-2845	301	14	25	25	NUM
fnp-2845	301	15	years	year	NOUN
fnp-2845	301	16	.	.	PUNCT
fnp-2845	302	1	embo	embo	NOUN
fnp-2845	302	2	mol	mol	ADP
fnp-2845	302	3	med	med	PROPN
fnp-2845	302	4	.	.	PUNCT
fnp-2845	303	1	2016;8(6):595	2016;8(6):595	NUM
fnp-2845	303	2	-	-	SYM
fnp-2845	303	3	608	608	NUM
fnp-2845	303	4	.	.	PUNCT
fnp-2845	304	1	20	20	NUM
fnp-2845	304	2	.	.	PUNCT
fnp-2845	305	1	hardy	hardy	PROPN
fnp-2845	305	2	j	j	PROPN
fnp-2845	305	3	,	,	PUNCT
fnp-2845	305	4	selkoe	selkoe	PROPN
fnp-2845	305	5	dj	dj	NOUN
fnp-2845	305	6	.	.	PUNCT
fnp-2845	306	1	the	the	DET
fnp-2845	306	2	amyloid	amyloid	NOUN
fnp-2845	306	3	hypothesis	hypothesis	NOUN
fnp-2845	306	4	of	of	ADP
fnp-2845	306	5	alzheimer	alzheimer	PROPN
fnp-2845	306	6	's	's	PART
fnp-2845	306	7	disease	disease	NOUN
fnp-2845	306	8	:	:	PUNCT
fnp-2845	306	9	progress	progress	NOUN
fnp-2845	306	10	and	and	CCONJ
fnp-2845	306	11	problems	problem	NOUN
fnp-2845	306	12	on	on	ADP
fnp-2845	306	13	the	the	DET
fnp-2845	306	14	road	road	NOUN
fnp-2845	306	15	to	to	ADP
fnp-2845	306	16	therapeutics	therapeutic	NOUN
fnp-2845	306	17	.	.	PUNCT
fnp-2845	307	1	science	science	NOUN
fnp-2845	307	2	.	.	PUNCT
fnp-2845	308	1	2002;297(5580):353	2002;297(5580):353	NUM
fnp-2845	308	2	-	-	SYM
fnp-2845	308	3	6	6	NUM
fnp-2845	308	4	.	.	NUM
fnp-2845	308	5	21	21	NUM
fnp-2845	308	6	.	.	PUNCT
fnp-2845	309	1	braak	braak	PROPN
fnp-2845	309	2	h	h	PROPN
fnp-2845	309	3	,	,	PUNCT
fnp-2845	309	4	del	del	PROPN
fnp-2845	309	5	tredici	tredici	PROPN
fnp-2845	309	6	k.	k.	PROPN
fnp-2845	310	1	the	the	DET
fnp-2845	310	2	pathological	pathological	ADJ
fnp-2845	310	3	process	process	NOUN
fnp-2845	310	4	underlying	underlie	VERB
fnp-2845	310	5	alzheimer	alzheimer	NOUN
fnp-2845	310	6	's	's	PART
fnp-2845	310	7	disease	disease	NOUN
fnp-2845	310	8	in	in	ADP
fnp-2845	310	9	individuals	individual	NOUN
fnp-2845	310	10	under	under	ADP
fnp-2845	310	11	thirty	thirty	NUM
fnp-2845	310	12	.	.	PUNCT
fnp-2845	311	1	acta	acta	PROPN
fnp-2845	311	2	neuropathol	neuropathol	PROPN
fnp-2845	311	3	.	.	PUNCT
fnp-2845	312	1	2011;121(2):171	2011;121(2):171	NUM
fnp-2845	312	2	-	-	SYM
fnp-2845	312	3	81	81	NUM
fnp-2845	312	4	.	.	PUNCT
fnp-2845	313	1	22	22	NUM
fnp-2845	313	2	.	.	PUNCT
fnp-2845	314	1	braak	braak	PROPN
fnp-2845	314	2	h	h	PROPN
fnp-2845	314	3	,	,	PUNCT
fnp-2845	314	4	thal	thal	PROPN
fnp-2845	314	5	dr	dr	PROPN
fnp-2845	314	6	,	,	PUNCT
fnp-2845	314	7	ghebremedhin	ghebremedhin	NOUN
fnp-2845	314	8	e	e	NOUN
fnp-2845	314	9	,	,	PUNCT
fnp-2845	314	10	del	del	PROPN
fnp-2845	314	11	tredici	tredici	PROPN
fnp-2845	314	12	k.	k.	PROPN
fnp-2845	314	13	stages	stage	NOUN
fnp-2845	314	14	of	of	ADP
fnp-2845	314	15	the	the	DET
fnp-2845	314	16	pathologic	pathologic	ADJ
fnp-2845	314	17	process	process	NOUN
fnp-2845	314	18	in	in	ADP
fnp-2845	314	19	alzheimer	alzheimer	PROPN
fnp-2845	314	20	disease	disease	NOUN
fnp-2845	314	21	:	:	PUNCT
fnp-2845	314	22	age	age	NOUN
fnp-2845	314	23	categories	category	NOUN
fnp-2845	314	24	from	from	ADP
fnp-2845	314	25	1	1	NUM
fnp-2845	314	26	to	to	PART
fnp-2845	314	27	100	100	NUM
fnp-2845	314	28	years	year	NOUN
fnp-2845	314	29	.	.	PUNCT
fnp-2845	315	1	j	j	PROPN
fnp-2845	315	2	neuropathol	neuropathol	PROPN
fnp-2845	315	3	exp	exp	PROPN
fnp-2845	315	4	neurol	neurol	NOUN
fnp-2845	315	5	.	.	PUNCT
fnp-2845	316	1	2011;70(11):960	2011;70(11):960	NUM
fnp-2845	316	2	-	-	SYM
fnp-2845	316	3	9	9	NUM
fnp-2845	316	4	.	.	NOUN
fnp-2845	316	5	23	23	NUM
fnp-2845	316	6	.	.	PUNCT
fnp-2845	317	1	streit	streit	PROPN
fnp-2845	317	2	wj	wj	PROPN
fnp-2845	317	3	,	,	PUNCT
fnp-2845	317	4	braak	braak	PROPN
fnp-2845	317	5	h	h	PROPN
fnp-2845	317	6	,	,	PUNCT
fnp-2845	317	7	del	del	PROPN
fnp-2845	317	8	tredici	tredici	PROPN
fnp-2845	317	9	k	k	PROPN
fnp-2845	317	10	,	,	PUNCT
fnp-2845	317	11	leyh	leyh	PROPN
fnp-2845	317	12	j	j	PROPN
fnp-2845	317	13	,	,	PUNCT
fnp-2845	317	14	lier	lier	PROPN
fnp-2845	317	15	j	j	PROPN
fnp-2845	317	16	,	,	PUNCT
fnp-2845	317	17	khoshbouei	khoshbouei	PROPN
fnp-2845	317	18	h	h	PROPN
fnp-2845	317	19	,	,	PUNCT
fnp-2845	317	20	et	et	PROPN
fnp-2845	317	21	al	al	PROPN
fnp-2845	317	22	.	.	PROPN
fnp-2845	317	23	microglial	microglial	ADJ
fnp-2845	317	24	activation	activation	NOUN
fnp-2845	317	25	occurs	occur	VERB
fnp-2845	317	26	late	late	ADV
fnp-2845	317	27	during	during	ADP
fnp-2845	317	28	preclinical	preclinical	ADJ
fnp-2845	317	29	alzheimer	alzheimer	NOUN
fnp-2845	317	30	's	's	PART
fnp-2845	317	31	disease	disease	NOUN
fnp-2845	317	32	.	.	PUNCT
fnp-2845	318	1	glia	glia	PROPN
fnp-2845	318	2	.	.	PUNCT
fnp-2845	319	1	2018;66(12):2550	2018;66(12):2550	NUM
fnp-2845	319	2	-	-	SYM
fnp-2845	319	3	62	62	NUM
fnp-2845	319	4	.	.	PUNCT
fnp-2845	320	1	24	24	NUM
fnp-2845	320	2	.	.	PUNCT
fnp-2845	321	1	crary	crary	PROPN
fnp-2845	321	2	jf	jf	PROPN
fnp-2845	321	3	,	,	PUNCT
fnp-2845	321	4	trojanowski	trojanowski	PROPN
fnp-2845	321	5	jq	jq	PROPN
fnp-2845	321	6	,	,	PUNCT
fnp-2845	321	7	schneider	schneider	PROPN
fnp-2845	321	8	ja	ja	PROPN
fnp-2845	321	9	,	,	PUNCT
fnp-2845	321	10	abisambra	abisambra	VERB
fnp-2845	321	11	jf	jf	PROPN
fnp-2845	321	12	,	,	PUNCT
fnp-2845	321	13	abner	abner	PROPN
fnp-2845	321	14	el	el	PROPN
fnp-2845	321	15	,	,	PUNCT
fnp-2845	321	16	alafuzoff	alafuzoff	NOUN
fnp-2845	322	1	i	i	PRON
fnp-2845	322	2	,	,	PUNCT
fnp-2845	322	3	et	et	PROPN
fnp-2845	322	4	al	al	PROPN
fnp-2845	322	5	.	.	PROPN
fnp-2845	323	1	primary	primary	ADJ
fnp-2845	323	2	age	age	NOUN
fnp-2845	323	3	-	-	PUNCT
fnp-2845	323	4	related	relate	VERB
fnp-2845	323	5	tauopathy	tauopathy	NOUN
fnp-2845	323	6	(	(	PUNCT
fnp-2845	323	7	part	part	NOUN
fnp-2845	323	8	):	):	PUNCT
fnp-2845	323	9	a	a	DET
fnp-2845	323	10	common	common	ADJ
fnp-2845	323	11	pathology	pathology	NOUN
fnp-2845	323	12	associated	associate	VERB
fnp-2845	323	13	with	with	ADP
fnp-2845	323	14	human	human	ADJ
fnp-2845	323	15	aging	aging	NOUN
fnp-2845	323	16	.	.	PUNCT
fnp-2845	324	1	acta	acta	PROPN
fnp-2845	324	2	neuropathol	neuropathol	PROPN
fnp-2845	324	3	.	.	PUNCT
fnp-2845	325	1	2014;128(6):755	2014;128(6):755	NUM
fnp-2845	325	2	-	-	SYM
fnp-2845	325	3	66	66	NUM
fnp-2845	325	4	.	.	PUNCT
fnp-2845	326	1	25	25	NUM
fnp-2845	326	2	.	.	PUNCT
fnp-2845	327	1	kettenmann	kettenmann	PROPN
fnp-2845	327	2	h	h	PROPN
fnp-2845	327	3	,	,	PUNCT
fnp-2845	327	4	hanisch	hanisch	PROPN
fnp-2845	327	5	uk	uk	PROPN
fnp-2845	327	6	,	,	PUNCT
fnp-2845	327	7	noda	noda	PROPN
fnp-2845	327	8	m	m	PROPN
fnp-2845	327	9	,	,	PUNCT
fnp-2845	327	10	verkhratsky	verkhratsky	ADJ
fnp-2845	327	11	a.	a.	NOUN
fnp-2845	327	12	physiology	physiology	NOUN
fnp-2845	327	13	of	of	ADP
fnp-2845	327	14	microglia	microglia	PROPN
fnp-2845	327	15	.	.	PUNCT
fnp-2845	328	1	physiol	physiol	PROPN
fnp-2845	328	2	rev	rev	VERB
fnp-2845	328	3	.	.	PUNCT
fnp-2845	329	1	2011;91	2011;91	NUM
fnp-2845	329	2	.	.	NOUN
fnp-2845	330	1	26	26	NUM
fnp-2845	330	2	.	.	PUNCT
fnp-2845	331	1	paasila	paasila	PROPN
fnp-2845	331	2	pj	pj	PROPN
fnp-2845	331	3	,	,	PUNCT
fnp-2845	331	4	davies	davy	NOUN
fnp-2845	331	5	ds	ds	PROPN
fnp-2845	331	6	,	,	PUNCT
fnp-2845	331	7	kril	kril	PROPN
fnp-2845	331	8	jj	jj	PROPN
fnp-2845	331	9	,	,	PUNCT
fnp-2845	331	10	goldsbury	goldsbury	NOUN
fnp-2845	331	11	c	c	PROPN
fnp-2845	331	12	,	,	PUNCT
fnp-2845	331	13	sutherland	sutherland	PROPN
fnp-2845	331	14	gt	gt	PROPN
fnp-2845	331	15	.	.	PUNCT
fnp-2845	332	1	the	the	DET
fnp-2845	332	2	relationship	relationship	NOUN
fnp-2845	332	3	between	between	ADP
fnp-2845	332	4	the	the	DET
fnp-2845	332	5	morphological	morphological	ADJ
fnp-2845	332	6	subtypes	subtype	NOUN
fnp-2845	332	7	of	of	ADP
fnp-2845	332	8	microglia	microglia	NOUN
fnp-2845	332	9	and	and	CCONJ
fnp-2845	332	10	alzheimer	alzheimer	PROPN
fnp-2845	332	11	's	's	PART
fnp-2845	332	12	disease	disease	NOUN
fnp-2845	332	13	neuropathology	neuropathology	NOUN
fnp-2845	332	14	.	.	PUNCT
fnp-2845	333	1	brain	brain	NOUN
fnp-2845	333	2	pathol	pathol	NOUN
fnp-2845	333	3	.	.	PUNCT
fnp-2845	334	1	2019	2019	NUM
fnp-2845	334	2	.	.	PUNCT
fnp-2845	335	1	27	27	NUM
fnp-2845	335	2	.	.	PUNCT
fnp-2845	336	1	bachstetter	bachstetter	PROPN
fnp-2845	336	2	ad	ad	NOUN
fnp-2845	336	3	,	,	PUNCT
fnp-2845	336	4	van	van	PROPN
fnp-2845	336	5	eldik	eldik	NOUN
fnp-2845	336	6	lj	lj	PROPN
fnp-2845	336	7	,	,	PUNCT
fnp-2845	336	8	schmitt	schmitt	PROPN
fnp-2845	336	9	fa	fa	PROPN
fnp-2845	336	10	,	,	PUNCT
fnp-2845	336	11	neltner	neltner	PROPN
fnp-2845	336	12	jh	jh	PROPN
fnp-2845	336	13	,	,	PUNCT
fnp-2845	336	14	ighodaro	ighodaro	VERB
fnp-2845	336	15	et	et	PROPN
fnp-2845	336	16	,	,	PUNCT
fnp-2845	336	17	webster	webster	PROPN
fnp-2845	336	18	sj	sj	PROPN
fnp-2845	336	19	,	,	PUNCT
fnp-2845	336	20	et	et	PROPN
fnp-2845	336	21	al	al	PROPN
fnp-2845	336	22	.	.	PUNCT
fnp-2845	336	23	disease	disease	NOUN
fnp-2845	336	24	-	-	PUNCT
fnp-2845	336	25	related	relate	VERB
fnp-2845	336	26	microglia	microglia	ADJ
fnp-2845	336	27	heterogeneity	heterogeneity	NOUN
fnp-2845	336	28	in	in	ADP
fnp-2845	336	29	the	the	DET
fnp-2845	336	30	hippocampus	hippocampus	NOUN
fnp-2845	336	31	of	of	ADP
fnp-2845	336	32	alzheimer	alzheimer	PROPN
fnp-2845	336	33	's	's	PART
fnp-2845	336	34	disease	disease	NOUN
fnp-2845	336	35	,	,	PUNCT
fnp-2845	336	36	dementia	dementia	NOUN
fnp-2845	336	37	with	with	ADP
fnp-2845	336	38	lewy	lewy	PROPN
fnp-2845	336	39	bodies	body	NOUN
fnp-2845	336	40	,	,	PUNCT
fnp-2845	336	41	and	and	CCONJ
fnp-2845	336	42	hippocampal	hippocampal	ADJ
fnp-2845	336	43	sclerosis	sclerosis	NOUN
fnp-2845	336	44	of	of	ADP
fnp-2845	336	45	aging	aging	NOUN
fnp-2845	336	46	.	.	PUNCT
fnp-2845	337	1	acta	acta	PROPN
fnp-2845	337	2	neuropathol	neuropathol	PROPN
fnp-2845	337	3	commun	commun	PROPN
fnp-2845	337	4	.	.	PUNCT
fnp-2845	338	1	2015;3:32	2015;3:32	NOUN
fnp-2845	338	2	.	.	PUNCT
fnp-2845	339	1	28	28	NUM
fnp-2845	339	2	.	.	PUNCT
fnp-2845	340	1	streit	streit	PROPN
fnp-2845	340	2	wj	wj	PROPN
fnp-2845	340	3	,	,	PUNCT
fnp-2845	340	4	walter	walter	PROPN
fnp-2845	340	5	sa	sa	PROPN
fnp-2845	340	6	,	,	PUNCT
fnp-2845	340	7	pennell	pennell	PROPN
fnp-2845	340	8	na	na	PROPN
fnp-2845	340	9	.	.	PROPN
fnp-2845	340	10	reactive	reactive	ADJ
fnp-2845	340	11	microgliosis	microgliosis	PROPN
fnp-2845	340	12	.	.	PUNCT
fnp-2845	341	1	prog	prog	PROPN
fnp-2845	341	2	neurobiol	neurobiol	PROPN
fnp-2845	341	3	.	.	PUNCT
fnp-2845	342	1	1999;57(6):563	1999;57(6):563	PROPN
fnp-2845	342	2	-	-	PUNCT
fnp-2845	342	3	81	81	NUM
fnp-2845	342	4	.	.	PUNCT
fnp-2845	343	1	29	29	NUM
fnp-2845	343	2	.	.	PUNCT
fnp-2845	344	1	streit	streit	PROPN
fnp-2845	344	2	wj	wj	PROPN
fnp-2845	344	3	,	,	PUNCT
fnp-2845	344	4	sammons	sammons	PROPN
fnp-2845	344	5	nw	nw	PROPN
fnp-2845	344	6	,	,	PUNCT
fnp-2845	344	7	kuhns	kuhns	PROPN
fnp-2845	344	8	aj	aj	PROPN
fnp-2845	344	9	,	,	PUNCT
fnp-2845	344	10	sparks	spark	VERB
fnp-2845	344	11	dl	dl	PROPN
fnp-2845	344	12	.	.	PROPN
fnp-2845	344	13	dystrophic	dystrophic	ADJ
fnp-2845	344	14	microglia	microglia	NOUN
fnp-2845	344	15	in	in	ADP
fnp-2845	344	16	the	the	DET
fnp-2845	344	17	aging	age	VERB
fnp-2845	344	18	human	human	ADJ
fnp-2845	344	19	brain	brain	NOUN
fnp-2845	344	20	.	.	PUNCT
fnp-2845	345	1	glia	glia	NOUN
fnp-2845	345	2	.	.	PUNCT
fnp-2845	346	1	2004;45(2):208	2004;45(2):208	NUM
fnp-2845	346	2	-	-	SYM
fnp-2845	346	3	12	12	NUM
fnp-2845	346	4	.	.	PUNCT
fnp-2845	346	5	30	30	NUM
fnp-2845	346	6	.	.	PUNCT
fnp-2845	347	1	streit	streit	PROPN
fnp-2845	347	2	wj	wj	PROPN
fnp-2845	347	3	,	,	PUNCT
fnp-2845	347	4	braak	braak	PROPN
fnp-2845	347	5	h	h	PROPN
fnp-2845	347	6	,	,	PUNCT
fnp-2845	347	7	xue	xue	PROPN
fnp-2845	347	8	qs	qs	PROPN
fnp-2845	347	9	,	,	PUNCT
fnp-2845	347	10	bechmann	bechmann	PROPN
fnp-2845	347	11	i.	i.	PROPN
fnp-2845	347	12	dystrophic	dystrophic	PROPN
fnp-2845	347	13	(	(	PUNCT
fnp-2845	347	14	senescent	senescent	NOUN
fnp-2845	347	15	)	)	PUNCT
fnp-2845	347	16	rather	rather	ADV
fnp-2845	347	17	than	than	ADP
fnp-2845	347	18	activated	activate	VERB
fnp-2845	347	19	microglial	microglial	ADJ
fnp-2845	347	20	cells	cell	NOUN
fnp-2845	347	21	are	be	AUX
fnp-2845	347	22	associated	associate	VERB
fnp-2845	347	23	with	with	ADP
fnp-2845	347	24	tau	tau	PROPN
fnp-2845	347	25	pathology	pathology	NOUN
fnp-2845	347	26	and	and	CCONJ
fnp-2845	347	27	likely	likely	ADV
fnp-2845	347	28	precede	precede	VERB
fnp-2845	347	29	neurodegeneration	neurodegeneration	NOUN
fnp-2845	347	30	in	in	ADP
fnp-2845	347	31	alzheimer	alzheimer	PROPN
fnp-2845	347	32	's	's	PART
fnp-2845	347	33	disease	disease	NOUN
fnp-2845	347	34	.	.	PUNCT
fnp-2845	348	1	acta	acta	PROPN
fnp-2845	348	2	neuropathol	neuropathol	PROPN
fnp-2845	348	3	.	.	PUNCT
fnp-2845	349	1	2009;118(4):475	2009;118(4):475	NUM
fnp-2845	349	2	-	-	SYM
fnp-2845	349	3	85	85	NUM
fnp-2845	349	4	.	.	PUNCT
fnp-2845	350	1	31	31	NUM
fnp-2845	350	2	.	.	PUNCT
fnp-2845	351	1	tischer	tischer	PROPN
fnp-2845	351	2	j	j	PROPN
fnp-2845	351	3	,	,	PUNCT
fnp-2845	351	4	krueger	krueger	PROPN
fnp-2845	351	5	m	m	PROPN
fnp-2845	351	6	,	,	PUNCT
fnp-2845	351	7	mueller	mueller	PROPN
fnp-2845	351	8	w	w	PROPN
fnp-2845	351	9	,	,	PUNCT
fnp-2845	351	10	staszewski	staszewski	PROPN
fnp-2845	351	11	o	o	PROPN
fnp-2845	351	12	,	,	PUNCT
fnp-2845	351	13	prinz	prinz	PROPN
fnp-2845	351	14	m	m	PROPN
fnp-2845	351	15	,	,	PUNCT
fnp-2845	351	16	streit	streit	PROPN
fnp-2845	351	17	wj	wj	PROPN
fnp-2845	351	18	,	,	PUNCT
fnp-2845	351	19	et	et	PROPN
fnp-2845	351	20	al	al	PROPN
fnp-2845	351	21	.	.	PUNCT
fnp-2845	352	1	inhomogeneous	inhomogeneous	ADJ
fnp-2845	352	2	distribution	distribution	NOUN
fnp-2845	352	3	of	of	ADP
fnp-2845	352	4	iba-1	iba-1	PUNCT
fnp-2845	352	5	characterizes	characterize	VERB
fnp-2845	352	6	microglial	microglial	ADJ
fnp-2845	352	7	pathology	pathology	NOUN
fnp-2845	352	8	in	in	ADP
fnp-2845	352	9	alzheimer	alzheimer	PROPN
fnp-2845	352	10	's	's	PART
fnp-2845	352	11	disease	disease	NOUN
fnp-2845	352	12	.	.	PUNCT
fnp-2845	353	1	glia	glia	PROPN
fnp-2845	353	2	.	.	PUNCT
fnp-2845	354	1	2016;64(9):1562	2016;64(9):1562	NUM
fnp-2845	354	2	-	-	SYM
fnp-2845	354	3	72	72	NUM
fnp-2845	354	4	.	.	PUNCT
fnp-2845	355	1	32	32	NUM
fnp-2845	355	2	.	.	PUNCT
fnp-2845	356	1	sanchez	sanchez	NOUN
fnp-2845	356	2	-	-	PUNCT
fnp-2845	356	3	mejias	mejias	PROPN
fnp-2845	356	4	e	e	NOUN
fnp-2845	356	5	,	,	PUNCT
fnp-2845	356	6	navarro	navarro	PROPN
fnp-2845	356	7	v	v	PROPN
fnp-2845	356	8	,	,	PUNCT
fnp-2845	356	9	jimenez	jimenez	PROPN
fnp-2845	356	10	s	s	PROPN
fnp-2845	356	11	,	,	PUNCT
fnp-2845	356	12	sanchez	sanchez	PROPN
fnp-2845	356	13	-	-	PUNCT
fnp-2845	356	14	mico	mico	PROPN
fnp-2845	356	15	m	m	PROPN
fnp-2845	356	16	,	,	PUNCT
fnp-2845	356	17	sanchez	sanchez	NOUN
fnp-2845	356	18	-	-	PUNCT
fnp-2845	356	19	varo	varo	PROPN
fnp-2845	356	20	r	r	NOUN
fnp-2845	356	21	,	,	PUNCT
fnp-2845	356	22	nunez	nunez	PROPN
fnp-2845	356	23	-	-	PUNCT
fnp-2845	356	24	diaz	diaz	PROPN
fnp-2845	357	1	c	c	AUX
fnp-2845	357	2	,	,	PUNCT
fnp-2845	357	3	et	et	PROPN
fnp-2845	357	4	al	al	PROPN
fnp-2845	357	5	.	.	PROPN
fnp-2845	358	1	soluble	soluble	ADJ
fnp-2845	358	2	phospho	phospho	NOUN
fnp-2845	358	3	-	-	PUNCT
fnp-2845	358	4	tau	tau	PROPN
fnp-2845	358	5	from	from	ADP
fnp-2845	358	6	alzheimer	alzheimer	PROPN
fnp-2845	358	7	's	's	PART
fnp-2845	358	8	disease	disease	NOUN
fnp-2845	358	9	hippocampus	hippocampus	NOUN
fnp-2845	358	10	drives	drive	VERB
fnp-2845	358	11	microglial	microglial	ADJ
fnp-2845	358	12	degeneration	degeneration	NOUN
fnp-2845	358	13	.	.	PUNCT
fnp-2845	359	1	acta	acta	PROPN
fnp-2845	359	2	neuropathol	neuropathol	PROPN
fnp-2845	359	3	.	.	PUNCT
fnp-2845	360	1	2016;132(6):897	2016;132(6):897	NUM
fnp-2845	360	2	-	-	SYM
fnp-2845	360	3	916	916	NUM
fnp-2845	360	4	.	.	PUNCT
fnp-2845	361	1	33	33	NUM
fnp-2845	361	2	.	.	PUNCT
fnp-2845	361	3	walker	walker	PROPN
fnp-2845	361	4	dg	dg	PROPN
fnp-2845	361	5	,	,	PUNCT
fnp-2845	361	6	tang	tang	PROPN
fnp-2845	361	7	tm	tm	PROPN
fnp-2845	361	8	,	,	PUNCT
fnp-2845	361	9	mendsaikhan	mendsaikhan	PROPN
fnp-2845	361	10	a	a	PRON
fnp-2845	361	11	,	,	PUNCT
fnp-2845	361	12	tooyama	tooyama	NOUN
fnp-2845	361	13	i	i	PRON
fnp-2845	361	14	,	,	PUNCT
fnp-2845	361	15	serrano	serrano	PROPN
fnp-2845	361	16	ge	ge	PROPN
fnp-2845	361	17	,	,	PUNCT
fnp-2845	361	18	sue	sue	PROPN
fnp-2845	361	19	li	li	PROPN
fnp-2845	361	20	,	,	PUNCT
fnp-2845	361	21	et	et	PROPN
fnp-2845	361	22	al	al	PROPN
fnp-2845	361	23	.	.	PUNCT
fnp-2845	361	24	patterns	pattern	NOUN
fnp-2845	361	25	of	of	ADP
fnp-2845	361	26	expression	expression	NOUN
fnp-2845	361	27	of	of	ADP
fnp-2845	361	28	purinergic	purinergic	NOUN
fnp-2845	361	29	receptor	receptor	NOUN
fnp-2845	361	30	p2ry12	p2ry12	PROPN
fnp-2845	361	31	,	,	PUNCT
fnp-2845	361	32	a	a	DET
fnp-2845	361	33	putative	putative	ADJ
fnp-2845	361	34	marker	marker	NOUN
fnp-2845	361	35	for	for	ADP
fnp-2845	361	36	non	non	ADJ
fnp-2845	361	37	-	-	ADJ
fnp-2845	361	38	activated	activated	ADJ
fnp-2845	361	39	microglia	microglia	NOUN
fnp-2845	361	40	,	,	PUNCT
fnp-2845	361	41	in	in	ADP
fnp-2845	361	42	aged	aged	ADJ
fnp-2845	361	43	and	and	CCONJ
fnp-2845	361	44	alzheimer	alzheimer	PROPN
fnp-2845	361	45	's	's	PART
fnp-2845	361	46	disease	disease	NOUN
fnp-2845	361	47	brains	brain	NOUN
fnp-2845	361	48	.	.	PUNCT
fnp-2845	362	1	int	int	PROPN
fnp-2845	362	2	j	j	PROPN
fnp-2845	362	3	mol	mol	ADP
fnp-2845	362	4	sci	sci	PROPN
fnp-2845	362	5	.	.	PROPN
fnp-2845	362	6	2020;21(2	2020;21(2	NUM
fnp-2845	362	7	)	)	PUNCT
fnp-2845	362	8	.	.	PUNCT
fnp-2845	363	1	34	34	NUM
fnp-2845	363	2	.	.	PUNCT
fnp-2845	364	1	davies	davy	NOUN
fnp-2845	364	2	ds	ds	PROPN
fnp-2845	364	3	,	,	PUNCT
fnp-2845	364	4	ma	ma	PROPN
fnp-2845	364	5	j	j	PROPN
fnp-2845	364	6	,	,	PUNCT
fnp-2845	364	7	jegathees	jegathees	PROPN
fnp-2845	364	8	t	t	PROPN
fnp-2845	364	9	,	,	PUNCT
fnp-2845	364	10	goldsbury	goldsbury	NOUN
fnp-2845	364	11	c.	c.	PROPN
fnp-2845	364	12	microglia	microglia	PROPN
fnp-2845	364	13	show	show	PROPN
fnp-2845	364	14	altered	alter	VERB
fnp-2845	364	15	morphology	morphology	NOUN
fnp-2845	364	16	and	and	CCONJ
fnp-2845	364	17	reduced	reduce	VERB
fnp-2845	364	18	arborization	arborization	NOUN
fnp-2845	364	19	in	in	ADP
fnp-2845	364	20	human	human	ADJ
fnp-2845	364	21	brain	brain	NOUN
fnp-2845	364	22	during	during	ADP
fnp-2845	364	23	aging	age	VERB
fnp-2845	364	24	and	and	CCONJ
fnp-2845	364	25	alzheimer	alzheimer	NOUN
fnp-2845	364	26	's	's	PART
fnp-2845	364	27	disease	disease	NOUN
fnp-2845	364	28	.	.	PUNCT
fnp-2845	365	1	brain	brain	NOUN
fnp-2845	365	2	pathol	pathol	NOUN
fnp-2845	365	3	.	.	PUNCT
fnp-2845	366	1	2017;27(6):795	2017;27(6):795	NUM
fnp-2845	366	2	-	-	PUNCT
fnp-2845	366	3	808	808	NUM
fnp-2845	366	4	.	.	NOUN
fnp-2845	366	5	35	35	NUM
fnp-2845	366	6	.	.	PUNCT
fnp-2845	367	1	sutherland	sutherland	PROPN
fnp-2845	367	2	gt	gt	PROPN
fnp-2845	367	3	,	,	PUNCT
fnp-2845	367	4	sheedy	sheedy	PROPN
fnp-2845	367	5	d	d	PROPN
fnp-2845	367	6	,	,	PUNCT
fnp-2845	367	7	stevens	stevens	PROPN
fnp-2845	367	8	j	j	PROPN
fnp-2845	367	9	,	,	PUNCT
fnp-2845	367	10	mccrossin	mccrossin	PROPN
fnp-2845	367	11	t	t	PROPN
fnp-2845	367	12	,	,	PUNCT
fnp-2845	367	13	smith	smith	PROPN
fnp-2845	367	14	cc	cc	PROPN
fnp-2845	367	15	,	,	PUNCT
fnp-2845	367	16	van	van	PROPN
fnp-2845	367	17	roijen	roijen	PROPN
fnp-2845	367	18	m	m	PROPN
fnp-2845	367	19	,	,	PUNCT
fnp-2845	367	20	et	et	PROPN
fnp-2845	367	21	al	al	PROPN
fnp-2845	367	22	.	.	PUNCT
fnp-2845	368	1	the	the	DET
fnp-2845	368	2	nsw	nsw	PROPN
fnp-2845	368	3	brain	brain	NOUN
fnp-2845	368	4	tissue	tissue	NOUN
fnp-2845	368	5	resource	resource	NOUN
fnp-2845	368	6	centre	centre	NOUN
fnp-2845	368	7	:	:	PUNCT
fnp-2845	368	8	banking	banking	NOUN
fnp-2845	368	9	for	for	ADP
fnp-2845	368	10	alcohol	alcohol	NOUN
fnp-2845	368	11	and	and	CCONJ
fnp-2845	368	12	major	major	ADJ
fnp-2845	368	13	neuropsychiatric	neuropsychiatric	ADJ
fnp-2845	368	14	disorders	disorder	NOUN
fnp-2845	368	15	research	research	NOUN
fnp-2845	368	16	.	.	PUNCT
fnp-2845	369	1	alcohol	alcohol	NOUN
fnp-2845	369	2	.	.	PUNCT
fnp-2845	370	1	2016:33	2016:33	NUM
fnp-2845	370	2	-	-	SYM
fnp-2845	370	3	9	9	NUM
fnp-2845	370	4	.	.	NUM
fnp-2845	371	1	36	36	NUM
fnp-2845	371	2	.	.	PUNCT
fnp-2845	372	1	rahman	rahman	PROPN
fnp-2845	372	2	t	t	PROPN
fnp-2845	372	3	,	,	PUNCT
fnp-2845	372	4	davies	davy	NOUN
fnp-2845	372	5	ds	ds	PROPN
fnp-2845	372	6	,	,	PUNCT
fnp-2845	372	7	tannenberg	tannenberg	PROPN
fnp-2845	372	8	rk	rk	NOUN
fnp-2845	372	9	,	,	PUNCT
fnp-2845	372	10	fok	fok	NOUN
fnp-2845	372	11	s	s	PROPN
fnp-2845	372	12	,	,	PUNCT
fnp-2845	372	13	shepherd	shepherd	NOUN
fnp-2845	372	14	c	c	NOUN
fnp-2845	372	15	,	,	PUNCT
fnp-2845	372	16	dodd	dodd	PROPN
fnp-2845	372	17	pr	pr	PROPN
fnp-2845	372	18	,	,	PUNCT
fnp-2845	372	19	et	et	PROPN
fnp-2845	372	20	al	al	PROPN
fnp-2845	372	21	.	.	PROPN
fnp-2845	373	1	cofilin	cofilin	PROPN
fnp-2845	373	2	rods	rod	NOUN
fnp-2845	373	3	and	and	CCONJ
fnp-2845	373	4	aggregates	aggregate	NOUN
fnp-2845	373	5	concur	concur	VERB
fnp-2845	373	6	with	with	ADP
fnp-2845	373	7	tau	tau	PROPN
fnp-2845	373	8	pathology	pathology	NOUN
fnp-2845	373	9	and	and	CCONJ
fnp-2845	373	10	the	the	DET
fnp-2845	373	11	development	development	NOUN
fnp-2845	373	12	of	of	ADP
fnp-2845	373	13	alzheimer	alzheimer	PROPN
fnp-2845	373	14	's	's	PART
fnp-2845	373	15	disease	disease	NOUN
fnp-2845	373	16	.	.	PUNCT
fnp-2845	374	1	j	j	PROPN
fnp-2845	374	2	alzheimers	alzheimers	PROPN
fnp-2845	374	3	dis	dis	PROPN
fnp-2845	374	4	.	.	PUNCT
fnp-2845	375	1	2014;42(4):1443	2014;42(4):1443	NUM
fnp-2845	375	2	-	-	PUNCT
fnp-2845	375	3	60	60	NUM
fnp-2845	375	4	.	.	PUNCT
fnp-2845	376	1	37	37	NUM
fnp-2845	376	2	.	.	PUNCT
fnp-2845	377	1	kril	kril	PROPN
fnp-2845	377	2	jj	jj	PROPN
fnp-2845	377	3	,	,	PUNCT
fnp-2845	377	4	halliday	halliday	PROPN
fnp-2845	377	5	gm	gm	PROPN
fnp-2845	377	6	,	,	PUNCT
fnp-2845	377	7	svoboda	svoboda	PROPN
fnp-2845	377	8	md	md	PROPN
fnp-2845	377	9	,	,	PUNCT
fnp-2845	377	10	cartwright	cartwright	PROPN
fnp-2845	377	11	h.	h.	PROPN
fnp-2845	378	1	the	the	DET
fnp-2845	378	2	cerebral	cerebral	ADJ
fnp-2845	378	3	cortex	cortex	NOUN
fnp-2845	378	4	is	be	AUX
fnp-2845	378	5	damaged	damage	VERB
fnp-2845	378	6	in	in	ADP
fnp-2845	378	7	chronic	chronic	ADJ
fnp-2845	378	8	alcoholics	alcoholic	NOUN
fnp-2845	378	9	.	.	PUNCT
fnp-2845	379	1	neuroscience	neuroscience	NOUN
fnp-2845	379	2	.	.	PUNCT
fnp-2845	380	1	1997;79(4):983	1997;79(4):983	NUM
fnp-2845	380	2	-	-	SYM
fnp-2845	380	3	98	98	NUM
fnp-2845	380	4	.	.	PUNCT
fnp-2845	381	1	38	38	NUM
fnp-2845	381	2	.	.	PUNCT
fnp-2845	382	1	montine	montine	PROPN
fnp-2845	382	2	tj	tj	PROPN
fnp-2845	382	3	,	,	PUNCT
fnp-2845	382	4	phelps	phelps	PROPN
fnp-2845	382	5	ch	ch	PROPN
fnp-2845	382	6	,	,	PUNCT
fnp-2845	382	7	beach	beach	PROPN
fnp-2845	382	8	tg	tg	PROPN
fnp-2845	382	9	,	,	PUNCT
fnp-2845	382	10	bigio	bigio	NOUN
fnp-2845	382	11	eh	eh	INTJ
fnp-2845	382	12	,	,	PUNCT
fnp-2845	382	13	cairns	cairns	PROPN
fnp-2845	382	14	nj	nj	PROPN
fnp-2845	382	15	,	,	PUNCT
fnp-2845	382	16	dickson	dickson	PROPN
fnp-2845	382	17	dw	dw	PROPN
fnp-2845	382	18	,	,	PUNCT
fnp-2845	382	19	et	et	PROPN
fnp-2845	382	20	al	al	PROPN
fnp-2845	382	21	.	.	PROPN
fnp-2845	383	1	national	national	PROPN
fnp-2845	383	2	institute	institute	PROPN
fnp-2845	383	3	on	on	ADP
fnp-2845	383	4	aging	age	VERB
fnp-2845	383	5	-	-	PUNCT
fnp-2845	383	6	alzheimer	alzheimer	NOUN
fnp-2845	383	7	's	's	PART
fnp-2845	383	8	association	association	NOUN
fnp-2845	383	9	guidelines	guideline	NOUN
fnp-2845	383	10	for	for	ADP
fnp-2845	383	11	the	the	DET
fnp-2845	383	12	neuropathologic	neuropathologic	ADJ
fnp-2845	383	13	assessment	assessment	NOUN
fnp-2845	383	14	of	of	ADP
fnp-2845	383	15	alzheimer	alzheimer	PROPN
fnp-2845	383	16	's	's	PART
fnp-2845	383	17	disease	disease	NOUN
fnp-2845	383	18	:	:	PUNCT
fnp-2845	383	19	a	a	DET
fnp-2845	383	20	practical	practical	ADJ
fnp-2845	383	21	approach	approach	NOUN
fnp-2845	383	22	.	.	PUNCT
fnp-2845	384	1	acta	acta	PROPN
fnp-2845	384	2	neuropathol	neuropathol	PROPN
fnp-2845	384	3	.	.	PUNCT
fnp-2845	385	1	2012;123(1):1	2012;123(1):1	NUM
fnp-2845	385	2	-	-	SYM
fnp-2845	385	3	11	11	NUM
fnp-2845	385	4	.	.	NOUN
fnp-2845	385	5	39	39	NUM
fnp-2845	385	6	.	.	PUNCT
fnp-2845	386	1	hansra	hansra	PROPN
fnp-2845	386	2	gk	gk	PROPN
fnp-2845	386	3	,	,	PUNCT
fnp-2845	386	4	popov	popov	PROPN
fnp-2845	386	5	g	g	PROPN
fnp-2845	386	6	,	,	PUNCT
fnp-2845	386	7	banaczek	banaczek	PROPN
fnp-2845	386	8	po	po	PROPN
fnp-2845	386	9	,	,	PUNCT
fnp-2845	386	10	vogiatzis	vogiatzis	PROPN
fnp-2845	386	11	m	m	PROPN
fnp-2845	386	12	,	,	PUNCT
fnp-2845	386	13	jegathees	jegathees	PROPN
fnp-2845	386	14	t	t	PROPN
fnp-2845	386	15	,	,	PUNCT
fnp-2845	386	16	goldsbury	goldsbury	PROPN
fnp-2845	386	17	ce	ce	PROPN
fnp-2845	386	18	,	,	PUNCT
fnp-2845	386	19	et	et	PROPN
fnp-2845	386	20	al	al	PROPN
fnp-2845	386	21	.	.	PUNCT
fnp-2845	387	1	the	the	DET
fnp-2845	387	2	neuritic	neuritic	ADJ
fnp-2845	387	3	plaque	plaque	NOUN
fnp-2845	387	4	in	in	ADP
fnp-2845	387	5	alzheimer	alzheimer	PROPN
fnp-2845	387	6	's	's	PART
fnp-2845	387	7	disease	disease	NOUN
fnp-2845	387	8	:	:	PUNCT
fnp-2845	387	9	perivascular	perivascular	ADJ
fnp-2845	387	10	degeneration	degeneration	NOUN
fnp-2845	387	11	of	of	ADP
fnp-2845	387	12	neuronal	neuronal	ADJ
fnp-2845	387	13	processes	process	NOUN
fnp-2845	387	14	.	.	PUNCT
fnp-2845	388	1	neurobiology	neurobiology	NOUN
fnp-2845	388	2	of	of	ADP
fnp-2845	388	3	aging	aging	NOUN
fnp-2845	388	4	.	.	PUNCT
fnp-2845	389	1	2019	2019	NUM
fnp-2845	389	2	.	.	X
fnp-2845	390	1	40	40	NUM
fnp-2845	390	2	.	.	PUNCT
fnp-2845	391	1	uchida	uchida	PROPN
fnp-2845	391	2	y	y	PROPN
fnp-2845	391	3	,	,	PUNCT
fnp-2845	391	4	takahashi	takahashi	PROPN
fnp-2845	391	5	h.	h.	PROPN
fnp-2845	391	6	rapid	rapid	ADJ
fnp-2845	391	7	detection	detection	NOUN
fnp-2845	391	8	of	of	ADP
fnp-2845	391	9	abeta	abeta	NOUN
fnp-2845	391	10	deposits	deposit	NOUN
fnp-2845	391	11	in	in	ADP
fnp-2845	391	12	app	app	NOUN
fnp-2845	391	13	transgenic	transgenic	NOUN
fnp-2845	391	14	mice	mouse	NOUN
fnp-2845	391	15	by	by	ADP
fnp-2845	391	16	hoechst	hoechst	ADJ
fnp-2845	391	17	33342	33342	NUM
fnp-2845	391	18	.	.	PUNCT
fnp-2845	392	1	neurosci	neurosci	PROPN
fnp-2845	392	2	lett	lett	PROPN
fnp-2845	392	3	.	.	PUNCT
fnp-2845	393	1	2008;448(3):279	2008;448(3):279	NUM
fnp-2845	393	2	-	-	SYM
fnp-2845	393	3	81	81	NUM
fnp-2845	393	4	.	.	PUNCT
fnp-2845	394	1	41	41	NUM
fnp-2845	394	2	.	.	PUNCT
fnp-2845	395	1	murray	murray	PROPN
fnp-2845	395	2	me	i	PRON
fnp-2845	395	3	,	,	PUNCT
fnp-2845	395	4	graff	graff	PROPN
fnp-2845	395	5	-	-	PUNCT
fnp-2845	395	6	radford	radford	PROPN
fnp-2845	395	7	nr	nr	PROPN
fnp-2845	395	8	,	,	PUNCT
fnp-2845	395	9	ross	ross	PROPN
fnp-2845	395	10	oa	oa	PROPN
fnp-2845	395	11	,	,	PUNCT
fnp-2845	395	12	petersen	petersen	PROPN
fnp-2845	395	13	rc	rc	PROPN
fnp-2845	395	14	,	,	PUNCT
fnp-2845	395	15	duara	duara	PROPN
fnp-2845	395	16	r	r	PROPN
fnp-2845	395	17	,	,	PUNCT
fnp-2845	395	18	dickson	dickson	PROPN
fnp-2845	395	19	dw	dw	PROPN
fnp-2845	395	20	.	.	PROPN
fnp-2845	395	21	neuropathologically	neuropathologically	ADV
fnp-2845	395	22	defined	define	VERB
fnp-2845	395	23	subtypes	subtype	NOUN
fnp-2845	395	24	of	of	ADP
fnp-2845	395	25	alzheimer	alzheimer	PROPN
fnp-2845	395	26	's	's	PART
fnp-2845	395	27	disease	disease	NOUN
fnp-2845	395	28	with	with	ADP
fnp-2845	395	29	distinct	distinct	ADJ
fnp-2845	395	30	clinical	clinical	ADJ
fnp-2845	395	31	characteristics	characteristic	NOUN
fnp-2845	395	32	:	:	PUNCT
fnp-2845	395	33	a	a	DET
fnp-2845	395	34	retrospective	retrospective	ADJ
fnp-2845	395	35	study	study	NOUN
fnp-2845	395	36	.	.	PUNCT
fnp-2845	396	1	lancet	lancet	PROPN
fnp-2845	396	2	neurol	neurol	PROPN
fnp-2845	396	3	.	.	PUNCT
fnp-2845	397	1	2011;10(9):785	2011;10(9):785	NUM
fnp-2845	397	2	-	-	SYM
fnp-2845	397	3	96	96	NUM
fnp-2845	397	4	.	.	PUNCT
fnp-2845	398	1	42	42	NUM
fnp-2845	398	2	.	.	PUNCT
fnp-2845	399	1	arendt	arendt	PROPN
fnp-2845	399	2	t	t	PROPN
fnp-2845	399	3	,	,	PUNCT
fnp-2845	399	4	bruckner	bruckner	PROPN
fnp-2845	399	5	mk	mk	PROPN
fnp-2845	399	6	,	,	PUNCT
fnp-2845	399	7	gertz	gertz	PROPN
fnp-2845	399	8	hj	hj	PROPN
fnp-2845	399	9	,	,	PUNCT
fnp-2845	399	10	marcova	marcova	PROPN
fnp-2845	399	11	l.	l.	PROPN
fnp-2845	399	12	cortical	cortical	ADJ
fnp-2845	399	13	distribution	distribution	NOUN
fnp-2845	399	14	of	of	ADP
fnp-2845	399	15	neurofibrillary	neurofibrillary	ADJ
fnp-2845	399	16	tangles	tangle	NOUN
fnp-2845	399	17	in	in	ADP
fnp-2845	399	18	alzheimer	alzheimer	PROPN
fnp-2845	399	19	's	's	PART
fnp-2845	399	20	disease	disease	NOUN
fnp-2845	399	21	matches	match	VERB
fnp-2845	399	22	the	the	DET
fnp-2845	399	23	pattern	pattern	NOUN
fnp-2845	399	24	of	of	ADP
fnp-2845	399	25	neurons	neuron	NOUN
fnp-2845	399	26	that	that	PRON
fnp-2845	399	27	retain	retain	VERB
fnp-2845	399	28	their	their	PRON
fnp-2845	399	29	capacity	capacity	NOUN
fnp-2845	399	30	of	of	ADP
fnp-2845	399	31	plastic	plastic	ADJ
fnp-2845	399	32	remodelling	remodelling	NOUN
fnp-2845	399	33	in	in	ADP
fnp-2845	399	34	the	the	DET
fnp-2845	399	35	adult	adult	NOUN
fnp-2845	399	36	brain	brain	NOUN
fnp-2845	399	37	.	.	PUNCT
fnp-2845	400	1	neuroscience	neuroscience	NOUN
fnp-2845	400	2	.	.	PUNCT
fnp-2845	401	1	1998;83(4):991	1998;83(4):991	NUM
fnp-2845	401	2	-	-	PUNCT
fnp-2845	401	3	1002	1002	NUM
fnp-2845	401	4	.	.	PUNCT
fnp-2845	402	1	43	43	NUM
fnp-2845	402	2	.	.	PUNCT
fnp-2845	403	1	geula	geula	PROPN
fnp-2845	403	2	c	c	PROPN
fnp-2845	403	3	,	,	PUNCT
fnp-2845	403	4	mesulam	mesulam	PROPN
fnp-2845	403	5	mm	mm	PROPN
fnp-2845	403	6	,	,	PUNCT
fnp-2845	403	7	saroff	saroff	PROPN
fnp-2845	403	8	dm	dm	PROPN
fnp-2845	403	9	,	,	PUNCT
fnp-2845	403	10	wu	wu	PROPN
fnp-2845	403	11	ck	ck	PROPN
fnp-2845	403	12	.	.	PROPN
fnp-2845	403	13	relationship	relationship	NOUN
fnp-2845	403	14	between	between	ADP
fnp-2845	403	15	plaques	plaque	NOUN
fnp-2845	403	16	,	,	PUNCT
fnp-2845	403	17	tangles	tangle	NOUN
fnp-2845	403	18	,	,	PUNCT
fnp-2845	403	19	and	and	CCONJ
fnp-2845	403	20	loss	loss	NOUN
fnp-2845	403	21	of	of	ADP
fnp-2845	403	22	cortical	cortical	ADJ
fnp-2845	403	23	cholinergic	cholinergic	ADJ
fnp-2845	403	24	fibers	fiber	NOUN
fnp-2845	403	25	in	in	ADP
fnp-2845	403	26	alzheimer	alzheimer	PROPN
fnp-2845	403	27	disease	disease	PROPN
fnp-2845	403	28	.	.	PUNCT
fnp-2845	404	1	j	j	PROPN
fnp-2845	404	2	neuropathol	neuropathol	PROPN
fnp-2845	404	3	exp	exp	PROPN
fnp-2845	404	4	neurol	neurol	NOUN
fnp-2845	404	5	.	.	PUNCT
fnp-2845	405	1	1998;57(1):63	1998;57(1):63	NUM
fnp-2845	405	2	-	-	SYM
fnp-2845	405	3	75	75	NUM
fnp-2845	405	4	.	.	PUNCT
fnp-2845	406	1	44	44	NUM
fnp-2845	406	2	.	.	PUNCT
fnp-2845	407	1	golaz	golaz	PROPN
fnp-2845	407	2	j	j	PROPN
fnp-2845	407	3	,	,	PUNCT
fnp-2845	407	4	bouras	bouras	NOUN
fnp-2845	407	5	c	c	NOUN
fnp-2845	407	6	,	,	PUNCT
fnp-2845	407	7	hof	hof	PROPN
fnp-2845	407	8	pr	pr	PROPN
fnp-2845	407	9	.	.	PUNCT
fnp-2845	408	1	motor	motor	NOUN
fnp-2845	408	2	cortex	cortex	NOUN
fnp-2845	408	3	involvement	involvement	NOUN
fnp-2845	408	4	in	in	ADP
fnp-2845	408	5	presenile	presenile	ADJ
fnp-2845	408	6	dementia	dementia	NOUN
fnp-2845	408	7	:	:	PUNCT
fnp-2845	408	8	report	report	NOUN
fnp-2845	408	9	of	of	ADP
fnp-2845	408	10	a	a	DET
fnp-2845	408	11	case	case	NOUN
fnp-2845	408	12	.	.	PUNCT
fnp-2845	409	1	j	j	PROPN
fnp-2845	409	2	geriatr	geriatr	ADJ
fnp-2845	409	3	psychiatry	psychiatry	NOUN
fnp-2845	409	4	neurol	neurol	NOUN
fnp-2845	409	5	.	.	PUNCT
fnp-2845	410	1	1992;5(2):85	1992;5(2):85	NUM
fnp-2845	410	2	-	-	SYM
fnp-2845	410	3	92	92	NUM
fnp-2845	410	4	.	.	PUNCT
fnp-2845	411	1	45	45	NUM
fnp-2845	411	2	.	.	PUNCT
fnp-2845	412	1	petersen	petersen	PROPN
fnp-2845	412	2	c	c	PROPN
fnp-2845	412	3	,	,	PUNCT
fnp-2845	412	4	nolan	nolan	PROPN
fnp-2845	412	5	al	al	PROPN
fnp-2845	412	6	,	,	PUNCT
fnp-2845	412	7	de	de	PROPN
fnp-2845	412	8	paula	paula	PROPN
fnp-2845	412	9	franca	franca	PROPN
fnp-2845	412	10	resende	resende	PROPN
fnp-2845	412	11	e	e	PROPN
fnp-2845	412	12	,	,	PUNCT
fnp-2845	412	13	miller	miller	PROPN
fnp-2845	412	14	z	z	PROPN
fnp-2845	412	15	,	,	PUNCT
fnp-2845	412	16	ehrenberg	ehrenberg	PROPN
fnp-2845	412	17	aj	aj	PROPN
fnp-2845	412	18	,	,	PUNCT
fnp-2845	412	19	gorno	gorno	PROPN
fnp-2845	412	20	-	-	PUNCT
fnp-2845	412	21	tempini	tempini	PROPN
fnp-2845	412	22	ml	ml	PROPN
fnp-2845	412	23	,	,	PUNCT
fnp-2845	412	24	et	et	PROPN
fnp-2845	412	25	al	al	PROPN
fnp-2845	412	26	.	.	PROPN
fnp-2845	412	27	alzheimer	alzheimer	PROPN
fnp-2845	412	28	's	's	PART
fnp-2845	412	29	disease	disease	NOUN
fnp-2845	412	30	clinical	clinical	ADJ
fnp-2845	412	31	variants	variant	NOUN
fnp-2845	412	32	show	show	VERB
fnp-2845	412	33	distinct	distinct	ADJ
fnp-2845	412	34	regional	regional	ADJ
fnp-2845	412	35	patterns	pattern	NOUN
fnp-2845	412	36	of	of	ADP
fnp-2845	412	37	neurofibrillary	neurofibrillary	ADJ
fnp-2845	412	38	tangle	tangle	NOUN
fnp-2845	412	39	accumulation	accumulation	NOUN
fnp-2845	412	40	.	.	PUNCT
fnp-2845	413	1	acta	acta	PROPN
fnp-2845	413	2	neuropathol	neuropathol	PROPN
fnp-2845	413	3	.	.	PUNCT
fnp-2845	414	1	2019;138(4):597	2019;138(4):597	NUM
fnp-2845	414	2	-	-	SYM
fnp-2845	414	3	612	612	NUM
fnp-2845	414	4	.	.	PUNCT
fnp-2845	415	1	46	46	NUM
fnp-2845	415	2	.	.	PUNCT
fnp-2845	416	1	suva	suva	PROPN
fnp-2845	416	2	d	d	PROPN
fnp-2845	416	3	,	,	PUNCT
fnp-2845	416	4	favre	favre	PROPN
fnp-2845	416	5	i	i	PRON
fnp-2845	416	6	,	,	PUNCT
fnp-2845	416	7	kraftsik	kraftsik	PROPN
fnp-2845	416	8	r	r	PROPN
fnp-2845	416	9	,	,	PUNCT
fnp-2845	416	10	esteban	esteban	PROPN
fnp-2845	416	11	m	m	PROPN
fnp-2845	416	12	,	,	PUNCT
fnp-2845	416	13	lobrinus	lobrinus	ADP
fnp-2845	416	14	a	a	PRON
fnp-2845	416	15	,	,	PUNCT
fnp-2845	416	16	miklossy	miklossy	ADJ
fnp-2845	416	17	j.	j.	PROPN
fnp-2845	416	18	primary	primary	PROPN
fnp-2845	416	19	motor	motor	PROPN
fnp-2845	416	20	cortex	cortex	NOUN
fnp-2845	416	21	involvement	involvement	NOUN
fnp-2845	416	22	in	in	ADP
fnp-2845	416	23	alzheimer	alzheimer	PROPN
fnp-2845	416	24	disease	disease	PROPN
fnp-2845	416	25	.	.	PUNCT
fnp-2845	417	1	j	j	PROPN
fnp-2845	417	2	neuropathol	neuropathol	PROPN
fnp-2845	417	3	exp	exp	PROPN
fnp-2845	417	4	neurol	neurol	PROPN
fnp-2845	417	5	.	.	PUNCT
fnp-2845	418	1	1999;58(11):1125	1999;58(11):1125	NUM
fnp-2845	418	2	-	-	SYM
fnp-2845	418	3	34	34	NUM
fnp-2845	418	4	.	.	PUNCT
fnp-2845	419	1	47	47	NUM
fnp-2845	419	2	.	.	PUNCT
fnp-2845	420	1	arnold	arnold	PROPN
fnp-2845	420	2	se	se	PROPN
fnp-2845	420	3	,	,	PUNCT
fnp-2845	420	4	hyman	hyman	PROPN
fnp-2845	420	5	bt	bt	PROPN
fnp-2845	420	6	,	,	PUNCT
fnp-2845	420	7	flory	flory	PROPN
fnp-2845	420	8	j	j	PROPN
fnp-2845	420	9	,	,	PUNCT
fnp-2845	420	10	damasio	damasio	PROPN
fnp-2845	420	11	ar	ar	PROPN
fnp-2845	420	12	,	,	PUNCT
fnp-2845	420	13	van	van	PROPN
fnp-2845	420	14	hoesen	hoesen	NOUN
fnp-2845	420	15	gw	gw	PROPN
fnp-2845	420	16	.	.	PUNCT
fnp-2845	421	1	the	the	DET
fnp-2845	421	2	topographical	topographical	ADJ
fnp-2845	421	3	and	and	CCONJ
fnp-2845	421	4	neuroanatomical	neuroanatomical	ADJ
fnp-2845	421	5	distribution	distribution	NOUN
fnp-2845	421	6	of	of	ADP
fnp-2845	421	7	neurofibrillary	neurofibrillary	ADJ
fnp-2845	421	8	tangles	tangle	NOUN
fnp-2845	421	9	and	and	CCONJ
fnp-2845	421	10	neuritic	neuritic	ADJ
fnp-2845	421	11	plaques	plaque	NOUN
fnp-2845	421	12	in	in	ADP
fnp-2845	421	13	the	the	DET
fnp-2845	421	14	cerebral	cerebral	ADJ
fnp-2845	421	15	cortex	cortex	NOUN
fnp-2845	421	16	of	of	ADP
fnp-2845	421	17	patients	patient	NOUN
fnp-2845	421	18	with	with	ADP
fnp-2845	421	19	alzheimer	alzheimer	PROPN
fnp-2845	421	20	's	's	PART
fnp-2845	421	21	disease	disease	NOUN
fnp-2845	421	22	.	.	PUNCT
fnp-2845	422	1	cereb	cereb	PROPN
fnp-2845	422	2	cortex	cortex	PROPN
fnp-2845	422	3	.	.	PUNCT
fnp-2845	423	1	1991;1(1):103	1991;1(1):103	NUM
fnp-2845	423	2	-	-	SYM
fnp-2845	423	3	16	16	NUM
fnp-2845	423	4	.	.	PUNCT
fnp-2845	424	1	48	48	NUM
fnp-2845	424	2	.	.	PUNCT
fnp-2845	425	1	genç	genç	PROPN
fnp-2845	425	2	b	b	PROPN
fnp-2845	425	3	,	,	PUNCT
fnp-2845	425	4	jara	jara	PROPN
fnp-2845	425	5	jh	jh	PROPN
fnp-2845	425	6	,	,	PUNCT
fnp-2845	425	7	lagrimas	lagrimas	PROPN
fnp-2845	425	8	akb	akb	PROPN
fnp-2845	425	9	,	,	PUNCT
fnp-2845	425	10	pytel	pytel	NOUN
fnp-2845	425	11	p	p	NOUN
fnp-2845	425	12	,	,	PUNCT
fnp-2845	425	13	roos	roos	PROPN
fnp-2845	425	14	rp	rp	PROPN
fnp-2845	425	15	,	,	PUNCT
fnp-2845	425	16	mesulam	mesulam	PROPN
fnp-2845	425	17	mm	mm	PROPN
fnp-2845	425	18	,	,	PUNCT
fnp-2845	425	19	et	et	PROPN
fnp-2845	425	20	al	al	PROPN
fnp-2845	425	21	.	.	PUNCT
fnp-2845	425	22	apical	apical	ADJ
fnp-2845	425	23	dendrite	dendrite	ADJ
fnp-2845	425	24	degeneration	degeneration	NOUN
fnp-2845	425	25	,	,	PUNCT
fnp-2845	425	26	a	a	DET
fnp-2845	425	27	novel	novel	ADJ
fnp-2845	425	28	cellular	cellular	ADJ
fnp-2845	425	29	pathology	pathology	NOUN
fnp-2845	425	30	for	for	ADP
fnp-2845	425	31	betz	betz	PROPN
fnp-2845	425	32	cells	cell	NOUN
fnp-2845	425	33	in	in	ADP
fnp-2845	425	34	als	al	NOUN
fnp-2845	425	35	.	.	PUNCT
fnp-2845	426	1	scientific	scientific	ADJ
fnp-2845	426	2	reports	report	NOUN
fnp-2845	426	3	.	.	PUNCT
fnp-2845	427	1	2017;7:41765-	2017;7:41765-	X
fnp-2845	427	2	.	.	NOUN
fnp-2845	427	3	49	49	NUM
fnp-2845	427	4	.	.	PUNCT
fnp-2845	428	1	shen	shen	PROPN
fnp-2845	429	1	z	z	PROPN
fnp-2845	429	2	,	,	PUNCT
fnp-2845	429	3	bao	bao	PROPN
fnp-2845	429	4	x	x	PROPN
fnp-2845	429	5	,	,	PUNCT
fnp-2845	429	6	wang	wang	PROPN
fnp-2845	429	7	r.	r.	PROPN
fnp-2845	429	8	clinical	clinical	PROPN
fnp-2845	429	9	pet	pet	ADJ
fnp-2845	429	10	imaging	imaging	NOUN
fnp-2845	429	11	of	of	ADP
fnp-2845	429	12	microglial	microglial	ADJ
fnp-2845	429	13	activation	activation	NOUN
fnp-2845	429	14	:	:	PUNCT
fnp-2845	429	15	implications	implication	NOUN
fnp-2845	429	16	for	for	ADP
fnp-2845	429	17	microglial	microglial	ADJ
fnp-2845	429	18	therapeutics	therapeutic	NOUN
fnp-2845	429	19	in	in	ADP
fnp-2845	429	20	alzheimer	alzheimer	PROPN
fnp-2845	429	21	's	's	PART
fnp-2845	429	22	disease	disease	NOUN
fnp-2845	429	23	.	.	PUNCT
fnp-2845	430	1	front	front	ADJ
fnp-2845	430	2	aging	age	VERB
fnp-2845	430	3	neurosci	neurosci	NOUN
fnp-2845	430	4	.	.	PUNCT
fnp-2845	431	1	2018;10:314-	2018;10:314-	NUM
fnp-2845	431	2	.	.	PROPN
fnp-2845	431	3	50	50	NUM
fnp-2845	431	4	.	.	PUNCT
fnp-2845	432	1	boza	boza	NOUN
fnp-2845	432	2	-	-	PUNCT
fnp-2845	432	3	serrano	serrano	NOUN
fnp-2845	432	4	a	a	NOUN
fnp-2845	432	5	,	,	PUNCT
fnp-2845	432	6	yang	yang	PROPN
fnp-2845	432	7	y	y	PROPN
fnp-2845	432	8	,	,	PUNCT
fnp-2845	432	9	paulus	paulus	PROPN
fnp-2845	432	10	a	a	PROPN
fnp-2845	432	11	,	,	PUNCT
fnp-2845	432	12	deierborg	deierborg	ADJ
fnp-2845	432	13	t.	t.	ADJ
fnp-2845	432	14	innate	innate	ADJ
fnp-2845	432	15	immune	immune	ADJ
fnp-2845	432	16	alterations	alteration	NOUN
fnp-2845	432	17	are	be	AUX
fnp-2845	432	18	elicited	elicit	VERB
fnp-2845	432	19	in	in	ADP
fnp-2845	432	20	microglial	microglial	ADJ
fnp-2845	432	21	cells	cell	NOUN
fnp-2845	432	22	before	before	ADP
fnp-2845	432	23	plaque	plaque	NOUN
fnp-2845	432	24	deposition	deposition	NOUN
fnp-2845	432	25	in	in	ADP
fnp-2845	432	26	the	the	DET
fnp-2845	432	27	alzheimer	alzheimer	PROPN
fnp-2845	432	28	’s	’s	PART
fnp-2845	432	29	disease	disease	NOUN
fnp-2845	432	30	mouse	mouse	PROPN
fnp-2845	432	31	model	model	NOUN
fnp-2845	432	32	5xfad	5xfad	NUM
fnp-2845	432	33	.	.	PUNCT
fnp-2845	433	1	scientific	scientific	ADJ
fnp-2845	433	2	reports	report	NOUN
fnp-2845	433	3	.	.	PUNCT
fnp-2845	434	1	2018;8(1):1550	2018;8(1):1550	X
fnp-2845	434	2	.	.	PROPN
fnp-2845	435	1	51	51	NUM
fnp-2845	435	2	.	.	PUNCT
fnp-2845	436	1	hong	hong	PROPN
fnp-2845	436	2	s	s	PROPN
fnp-2845	436	3	,	,	PUNCT
fnp-2845	436	4	beja	beja	PROPN
fnp-2845	436	5	-	-	PUNCT
fnp-2845	436	6	glasser	glasser	PROPN
fnp-2845	436	7	vf	vf	PROPN
fnp-2845	436	8	,	,	PUNCT
fnp-2845	436	9	nfonoyim	nfonoyim	PROPN
fnp-2845	436	10	bm	bm	PROPN
fnp-2845	436	11	,	,	PUNCT
fnp-2845	436	12	frouin	frouin	PROPN
fnp-2845	436	13	a	a	NOUN
fnp-2845	436	14	,	,	PUNCT
fnp-2845	436	15	li	li	PROPN
fnp-2845	436	16	s	s	PROPN
fnp-2845	436	17	,	,	PUNCT
fnp-2845	436	18	ramakrishnan	ramakrishnan	PROPN
fnp-2845	436	19	s	s	PROPN
fnp-2845	436	20	,	,	PUNCT
fnp-2845	436	21	et	et	PROPN
fnp-2845	436	22	al	al	PROPN
fnp-2845	436	23	.	.	PROPN
fnp-2845	436	24	complement	complement	PROPN
fnp-2845	436	25	and	and	CCONJ
fnp-2845	436	26	microglia	microglia	ADJ
fnp-2845	436	27	mediate	mediate	VERB
fnp-2845	436	28	early	early	ADJ
fnp-2845	436	29	synapse	synapse	NOUN
fnp-2845	436	30	loss	loss	NOUN
fnp-2845	436	31	in	in	ADP
fnp-2845	436	32	alzheimer	alzheimer	PROPN
fnp-2845	436	33	mouse	mouse	NOUN
fnp-2845	436	34	models	model	NOUN
fnp-2845	436	35	.	.	PUNCT
fnp-2845	437	1	science	science	NOUN
fnp-2845	437	2	.	.	PUNCT
fnp-2845	438	1	2016;352(6286):712	2016;352(6286):712	NUM
fnp-2845	438	2	-	-	SYM
fnp-2845	438	3	6	6	NUM
fnp-2845	438	4	.	.	NOUN
fnp-2845	438	5	52	52	NUM
fnp-2845	438	6	.	.	PUNCT
fnp-2845	439	1	cameron	cameron	PROPN
fnp-2845	439	2	b	b	PROPN
fnp-2845	439	3	,	,	PUNCT
fnp-2845	439	4	tse	tse	PROPN
fnp-2845	439	5	w	w	PROPN
fnp-2845	439	6	,	,	PUNCT
fnp-2845	439	7	lamb	lamb	PROPN
fnp-2845	439	8	r	r	PROPN
fnp-2845	439	9	,	,	PUNCT
fnp-2845	439	10	li	li	PROPN
fnp-2845	439	11	x	x	PROPN
fnp-2845	439	12	,	,	PUNCT
fnp-2845	439	13	lamb	lamb	PROPN
fnp-2845	439	14	bt	bt	PROPN
fnp-2845	439	15	,	,	PUNCT
fnp-2845	439	16	landreth	landreth	PROPN
fnp-2845	439	17	ge	ge	PROPN
fnp-2845	439	18	.	.	PUNCT
fnp-2845	440	1	loss	loss	NOUN
fnp-2845	440	2	of	of	ADP
fnp-2845	440	3	interleukin	interleukin	NOUN
fnp-2845	440	4	receptor	receptor	NOUN
fnp-2845	440	5	-	-	PUNCT
fnp-2845	440	6	associated	associate	VERB
fnp-2845	440	7	kinase	kinase	NOUN
fnp-2845	440	8	4	4	NUM
fnp-2845	440	9	signaling	signal	VERB
fnp-2845	440	10	suppresses	suppress	VERB
fnp-2845	440	11	amyloid	amyloid	NOUN
fnp-2845	440	12	pathology	pathology	NOUN
fnp-2845	440	13	and	and	CCONJ
fnp-2845	440	14	alters	alter	VERB
fnp-2845	440	15	microglial	microglial	ADJ
fnp-2845	440	16	phenotype	phenotype	NOUN
fnp-2845	440	17	in	in	ADP
fnp-2845	440	18	a	a	DET
fnp-2845	440	19	mouse	mouse	NOUN
fnp-2845	440	20	model	model	NOUN
fnp-2845	440	21	of	of	ADP
fnp-2845	440	22	alzheimer	alzheimer	PROPN
fnp-2845	440	23	's	's	PART
fnp-2845	440	24	disease	disease	NOUN
fnp-2845	440	25	.	.	PUNCT
fnp-2845	441	1	the	the	DET
fnp-2845	441	2	journal	journal	NOUN
fnp-2845	441	3	of	of	ADP
fnp-2845	441	4	neuroscience	neuroscience	NOUN
fnp-2845	441	5	.	.	PUNCT
fnp-2845	441	6	2012	2012	NUM
fnp-2845	441	7	;	;	PUNCT
fnp-2845	441	8	32(43):15112	32(43):15112	PROPN
fnp-2845	441	9	-	-	SYM
fnp-2845	441	10	23	23	NUM
fnp-2845	441	11	.	.	PUNCT
fnp-2845	442	1	53	53	NUM
fnp-2845	442	2	.	.	PUNCT
fnp-2845	443	1	halle	halle	PROPN
fnp-2845	443	2	a	a	PROPN
fnp-2845	443	3	,	,	PUNCT
fnp-2845	443	4	hornung	hornung	ADJ
fnp-2845	443	5	v	v	NOUN
fnp-2845	443	6	,	,	PUNCT
fnp-2845	443	7	petzold	petzold	PROPN
fnp-2845	443	8	gc	gc	PROPN
fnp-2845	443	9	,	,	PUNCT
fnp-2845	443	10	stewart	stewart	PROPN
fnp-2845	443	11	cr	cr	PROPN
fnp-2845	443	12	,	,	PUNCT
fnp-2845	443	13	monks	monks	PROPN
fnp-2845	443	14	bg	bg	PROPN
fnp-2845	443	15	,	,	PUNCT
fnp-2845	443	16	reinheckel	reinheckel	PROPN
fnp-2845	443	17	t	t	PROPN
fnp-2845	443	18	,	,	PUNCT
fnp-2845	443	19	et	et	PROPN
fnp-2845	443	20	al	al	PROPN
fnp-2845	443	21	.	.	PUNCT
fnp-2845	444	1	the	the	DET
fnp-2845	444	2	nalp3	nalp3	NOUN
fnp-2845	444	3	inflammasome	inflammasome	NOUN
fnp-2845	444	4	is	be	AUX
fnp-2845	444	5	involved	involve	VERB
fnp-2845	444	6	in	in	ADP
fnp-2845	444	7	the	the	DET
fnp-2845	444	8	innate	innate	ADJ
fnp-2845	444	9	immune	immune	ADJ
fnp-2845	444	10	response	response	NOUN
fnp-2845	444	11	to	to	ADP
fnp-2845	444	12	amyloid	amyloid	NOUN
fnp-2845	444	13	-	-	PUNCT
fnp-2845	444	14	beta	beta	NOUN
fnp-2845	444	15	.	.	PUNCT
fnp-2845	445	1	nat	nat	PROPN
fnp-2845	445	2	immunol	immunol	NOUN
fnp-2845	445	3	.	.	PUNCT
fnp-2845	446	1	2008;9(8):857	2008;9(8):857	X
fnp-2845	446	2	-	-	SYM
fnp-2845	446	3	65	65	NUM
fnp-2845	446	4	.	.	PUNCT
fnp-2845	447	1	54	54	NUM
fnp-2845	447	2	.	.	PUNCT
fnp-2845	448	1	salminen	salminen	PROPN
fnp-2845	448	2	a	a	PROPN
fnp-2845	448	3	,	,	PUNCT
fnp-2845	448	4	ojala	ojala	PROPN
fnp-2845	448	5	j	j	PROPN
fnp-2845	448	6	,	,	PUNCT
fnp-2845	448	7	kauppinen	kauppinen	PROPN
fnp-2845	448	8	a	a	X
fnp-2845	448	9	,	,	PUNCT
fnp-2845	448	10	kaarniranta	kaarniranta	NOUN
fnp-2845	448	11	k	k	PROPN
fnp-2845	448	12	,	,	PUNCT
fnp-2845	448	13	suuronen	suuronen	PROPN
fnp-2845	448	14	t.	t.	NOUN
fnp-2845	448	15	inflammation	inflammation	NOUN
fnp-2845	448	16	in	in	ADP
fnp-2845	448	17	alzheimer	alzheimer	PROPN
fnp-2845	448	18	's	's	PART
fnp-2845	448	19	disease	disease	NOUN
fnp-2845	448	20	:	:	PUNCT
fnp-2845	448	21	amyloid	amyloid	NOUN
fnp-2845	448	22	-	-	PUNCT
fnp-2845	448	23	beta	beta	NOUN
fnp-2845	448	24	oligomers	oligomer	NOUN
fnp-2845	448	25	trigger	trigger	NOUN
fnp-2845	448	26	innate	innate	ADJ
fnp-2845	448	27	immunity	immunity	NOUN
fnp-2845	448	28	defence	defence	NOUN
fnp-2845	448	29	via	via	ADP
fnp-2845	448	30	pattern	pattern	NOUN
fnp-2845	448	31	recognition	recognition	NOUN
fnp-2845	448	32	receptors	receptor	NOUN
fnp-2845	448	33	.	.	PUNCT
fnp-2845	449	1	prog	prog	PROPN
fnp-2845	449	2	neurobiol	neurobiol	PROPN
fnp-2845	449	3	.	.	PUNCT
fnp-2845	450	1	2009;87(3):181	2009;87(3):181	PROPN
fnp-2845	450	2	-	-	PUNCT
fnp-2845	450	3	94	94	NUM
fnp-2845	450	4	.	.	PUNCT
fnp-2845	451	1	55	55	NUM
fnp-2845	451	2	.	.	PUNCT
fnp-2845	452	1	heneka	heneka	PROPN
fnp-2845	452	2	mt	mt	PROPN
fnp-2845	452	3	,	,	PUNCT
fnp-2845	452	4	kummer	kummer	PROPN
fnp-2845	452	5	mp	mp	PROPN
fnp-2845	452	6	,	,	PUNCT
fnp-2845	452	7	stutz	stutz	VERB
fnp-2845	452	8	a	a	PRON
fnp-2845	452	9	,	,	PUNCT
fnp-2845	452	10	delekate	delekate	PROPN
fnp-2845	452	11	a	a	X
fnp-2845	452	12	,	,	PUNCT
fnp-2845	452	13	schwartz	schwartz	PROPN
fnp-2845	452	14	s	s	PROPN
fnp-2845	452	15	,	,	PUNCT
fnp-2845	452	16	vieira	vieira	NOUN
fnp-2845	452	17	-	-	PUNCT
fnp-2845	452	18	saecker	saecker	NOUN
fnp-2845	452	19	a	a	PRON
fnp-2845	452	20	,	,	PUNCT
fnp-2845	452	21	et	et	PROPN
fnp-2845	452	22	al	al	PROPN
fnp-2845	452	23	.	.	PUNCT
fnp-2845	453	1	nlrp3	nlrp3	PROPN
fnp-2845	453	2	is	be	AUX
fnp-2845	453	3	activated	activate	VERB
fnp-2845	453	4	in	in	ADP
fnp-2845	453	5	alzheimer	alzheimer	PROPN
fnp-2845	453	6	's	's	PART
fnp-2845	453	7	disease	disease	NOUN
fnp-2845	453	8	and	and	CCONJ
fnp-2845	453	9	contributes	contribute	VERB
fnp-2845	453	10	to	to	ADP
fnp-2845	453	11	pathology	pathology	NOUN
fnp-2845	453	12	in	in	ADP
fnp-2845	453	13	app	app	PROPN
fnp-2845	453	14	/	/	SYM
fnp-2845	453	15	ps1	ps1	NOUN
fnp-2845	453	16	mice	mouse	NOUN
fnp-2845	453	17	.	.	PUNCT
fnp-2845	454	1	nature	nature	NOUN
fnp-2845	454	2	.	.	PUNCT
fnp-2845	455	1	2013	2013	NUM
fnp-2845	455	2	;	;	PUNCT
fnp-2845	455	3	493(7434):674	493(7434):674	NUM
fnp-2845	455	4	-	-	SYM
fnp-2845	455	5	8	8	NUM
fnp-2845	455	6	.	.	X
fnp-2845	456	1	56	56	NUM
fnp-2845	456	2	.	.	PUNCT
fnp-2845	457	1	heneka	heneka	PROPN
fnp-2845	457	2	mt	mt	PROPN
fnp-2845	457	3	,	,	PUNCT
fnp-2845	457	4	golenbock	golenbock	NOUN
fnp-2845	457	5	dt	dt	NOUN
fnp-2845	457	6	,	,	PUNCT
fnp-2845	457	7	latz	latz	ADJ
fnp-2845	457	8	e.	e.	PROPN
fnp-2845	457	9	innate	innate	PROPN
fnp-2845	457	10	immunity	immunity	NOUN
fnp-2845	457	11	in	in	ADP
fnp-2845	457	12	alzheimer	alzheimer	PROPN
fnp-2845	457	13	's	's	PART
fnp-2845	457	14	disease	disease	NOUN
fnp-2845	457	15	.	.	PUNCT
fnp-2845	458	1	nat	nat	PROPN
fnp-2845	458	2	immunol	immunol	NOUN
fnp-2845	458	3	.	.	PUNCT
fnp-2845	459	1	2015;16(3):229	2015;16(3):229	NUM
fnp-2845	459	2	-	-	SYM
fnp-2845	459	3	36	36	NUM
fnp-2845	459	4	.	.	PUNCT
fnp-2845	460	1	57	57	NUM
fnp-2845	460	2	.	.	PUNCT
fnp-2845	461	1	heneka	heneka	PROPN
fnp-2845	461	2	mt	mt	PROPN
fnp-2845	461	3	,	,	PUNCT
fnp-2845	461	4	kummer	kummer	PROPN
fnp-2845	461	5	mp	mp	PROPN
fnp-2845	461	6	,	,	PUNCT
fnp-2845	461	7	latz	latz	ADJ
fnp-2845	461	8	e.	e.	PROPN
fnp-2845	461	9	innate	innate	ADJ
fnp-2845	461	10	immune	immune	ADJ
fnp-2845	461	11	activation	activation	NOUN
fnp-2845	461	12	in	in	ADP
fnp-2845	461	13	neurodegenerative	neurodegenerative	ADJ
fnp-2845	461	14	disease	disease	NOUN
fnp-2845	461	15	.	.	PUNCT
fnp-2845	462	1	nat	nat	PROPN
fnp-2845	462	2	rev	rev	PROPN
fnp-2845	462	3	immunol	immunol	NOUN
fnp-2845	462	4	.	.	PUNCT
fnp-2845	463	1	2014;14(7):463	2014;14(7):463	NUM
fnp-2845	463	2	-	-	SYM
fnp-2845	463	3	77	77	NUM
fnp-2845	463	4	.	.	PUNCT
fnp-2845	464	1	58	58	NUM
fnp-2845	464	2	.	.	PUNCT
fnp-2845	465	1	hanisch	hanisch	PROPN
fnp-2845	465	2	u	u	PROPN
fnp-2845	465	3	-	-	PROPN
fnp-2845	465	4	k	k	PROPN
fnp-2845	465	5	,	,	PUNCT
fnp-2845	465	6	kettenmann	kettenmann	PROPN
fnp-2845	465	7	h.	h.	PROPN
fnp-2845	465	8	microglia	microglia	PROPN
fnp-2845	465	9	:	:	PUNCT
fnp-2845	465	10	active	active	ADJ
fnp-2845	465	11	sensor	sensor	NOUN
fnp-2845	465	12	and	and	CCONJ
fnp-2845	465	13	versatile	versatile	ADJ
fnp-2845	465	14	effector	effector	NOUN
fnp-2845	465	15	cells	cell	NOUN
fnp-2845	465	16	in	in	ADP
fnp-2845	465	17	the	the	DET
fnp-2845	465	18	normal	normal	ADJ
fnp-2845	465	19	and	and	CCONJ
fnp-2845	465	20	pathologic	pathologic	ADJ
fnp-2845	465	21	brain	brain	NOUN
fnp-2845	465	22	.	.	PUNCT
fnp-2845	466	1	nat	nat	PROPN
fnp-2845	466	2	neurosci	neurosci	PROPN
fnp-2845	466	3	.	.	PUNCT
fnp-2845	467	1	2007;10(11):1387	2007;10(11):1387	NUM
fnp-2845	467	2	-	-	SYM
fnp-2845	467	3	94	94	NUM
fnp-2845	467	4	.	.	PUNCT
fnp-2845	468	1	59	59	NUM
fnp-2845	468	2	.	.	PUNCT
fnp-2845	469	1	koenigsknecht	koenigsknecht	NOUN
fnp-2845	469	2	-	-	PUNCT
fnp-2845	469	3	talboo	talboo	NOUN
fnp-2845	469	4	j	j	PROPN
fnp-2845	469	5	,	,	PUNCT
fnp-2845	469	6	landreth	landreth	PROPN
fnp-2845	469	7	ge	ge	PROPN
fnp-2845	469	8	.	.	PUNCT
fnp-2845	470	1	microglial	microglial	ADJ
fnp-2845	470	2	phagocytosis	phagocytosis	NOUN
fnp-2845	470	3	induced	induce	VERB
fnp-2845	470	4	by	by	ADP
fnp-2845	470	5	fibrillar	fibrillar	ADJ
fnp-2845	470	6	beta	beta	NOUN
fnp-2845	470	7	-	-	PUNCT
fnp-2845	470	8	amyloid	amyloid	NOUN
fnp-2845	470	9	and	and	CCONJ
fnp-2845	470	10	iggs	igg	NOUN
fnp-2845	470	11	are	be	AUX
fnp-2845	470	12	differentially	differentially	ADV
fnp-2845	470	13	regulated	regulate	VERB
fnp-2845	470	14	by	by	ADP
fnp-2845	470	15	proinflammatory	proinflammatory	ADJ
fnp-2845	470	16	cytokines	cytokine	NOUN
fnp-2845	470	17	.	.	PUNCT
fnp-2845	471	1	j	j	PROPN
fnp-2845	471	2	neurosci	neurosci	PROPN
fnp-2845	471	3	.	.	PUNCT
fnp-2845	472	1	2005;25(36):8240	2005;25(36):8240	NUM
fnp-2845	472	2	-	-	SYM
fnp-2845	472	3	9	9	NUM
fnp-2845	472	4	.	.	NOUN
fnp-2845	472	5	60	60	NUM
fnp-2845	472	6	.	.	PUNCT
fnp-2845	473	1	block	block	NOUN
fnp-2845	473	2	ml	ml	PROPN
fnp-2845	473	3	,	,	PUNCT
fnp-2845	473	4	zecca	zecca	NOUN
fnp-2845	473	5	l	l	NOUN
fnp-2845	473	6	,	,	PUNCT
fnp-2845	473	7	hong	hong	PROPN
fnp-2845	473	8	js	js	PROPN
fnp-2845	473	9	.	.	PUNCT
fnp-2845	474	1	microglia	microglia	ADJ
fnp-2845	474	2	-	-	PUNCT
fnp-2845	474	3	mediated	mediate	VERB
fnp-2845	474	4	neurotoxicity	neurotoxicity	NOUN
fnp-2845	474	5	:	:	PUNCT
fnp-2845	474	6	uncovering	uncover	VERB
fnp-2845	474	7	the	the	DET
fnp-2845	474	8	molecular	molecular	ADJ
fnp-2845	474	9	mechanisms	mechanism	NOUN
fnp-2845	474	10	.	.	PUNCT
fnp-2845	475	1	nat	nat	PROPN
fnp-2845	475	2	rev	rev	PROPN
fnp-2845	475	3	neurosci	neurosci	PROPN
fnp-2845	475	4	.	.	PUNCT
fnp-2845	476	1	2007;8(1):57	2007;8(1):57	NUM
fnp-2845	476	2	-	-	SYM
fnp-2845	476	3	69	69	NUM
fnp-2845	476	4	.	.	PUNCT
fnp-2845	477	1	61	61	NUM
fnp-2845	477	2	.	.	PUNCT
fnp-2845	478	1	howard	howard	PROPN
fnp-2845	478	2	r	r	PROPN
fnp-2845	478	3	,	,	PUNCT
fnp-2845	478	4	liu	liu	PROPN
fnp-2845	478	5	ky	ky	PROPN
fnp-2845	478	6	.	.	PUNCT
fnp-2845	479	1	questions	question	NOUN
fnp-2845	479	2	emerge	emerge	VERB
fnp-2845	479	3	as	as	ADP
fnp-2845	479	4	biogen	biogen	PROPN
fnp-2845	479	5	claims	claim	NOUN
fnp-2845	479	6	aducanumab	aducanumab	NOUN
fnp-2845	479	7	turnaround	turnaround	NOUN
fnp-2845	479	8	.	.	PUNCT
fnp-2845	480	1	nature	nature	NOUN
fnp-2845	480	2	reviews	review	VERB
fnp-2845	480	3	neurology	neurology	NOUN
fnp-2845	480	4	.	.	PUNCT
fnp-2845	481	1	2020;16(2):63	2020;16(2):63	NUM
fnp-2845	481	2	-	-	SYM
fnp-2845	481	3	4	4	NUM
fnp-2845	481	4	.	.	NUM
fnp-2845	481	5	62	62	NUM
fnp-2845	481	6	.	.	PUNCT
fnp-2845	482	1	cummings	cummings	PROPN
fnp-2845	482	2	j	j	PROPN
fnp-2845	482	3	,	,	PUNCT
fnp-2845	482	4	lee	lee	PROPN
fnp-2845	482	5	g	g	PROPN
fnp-2845	482	6	,	,	PUNCT
fnp-2845	482	7	ritter	ritter	PROPN
fnp-2845	482	8	a	a	PROPN
fnp-2845	482	9	,	,	PUNCT
fnp-2845	482	10	sabbagh	sabbagh	PROPN
fnp-2845	482	11	m	m	PROPN
fnp-2845	482	12	,	,	PUNCT
fnp-2845	482	13	zhong	zhong	PROPN
fnp-2845	482	14	k.	k.	PROPN
fnp-2845	482	15	alzheimer	alzheimer	PROPN
fnp-2845	482	16	's	's	PART
fnp-2845	482	17	disease	disease	NOUN
fnp-2845	482	18	drug	drug	NOUN
fnp-2845	482	19	development	development	NOUN
fnp-2845	482	20	pipeline	pipeline	NOUN
fnp-2845	482	21	:	:	PUNCT
fnp-2845	482	22	2019	2019	NUM
fnp-2845	482	23	.	.	PUNCT
fnp-2845	483	1	alzheimers	alzheimers	PROPN
fnp-2845	483	2	dement	dement	PROPN
fnp-2845	483	3	(	(	PUNCT
fnp-2845	483	4	n	n	NOUN
fnp-2845	483	5	y	y	NOUN
fnp-2845	483	6	)	)	PUNCT
fnp-2845	483	7	.	.	PUNCT
fnp-2845	484	1	2019;5:272	2019;5:272	PROPN
fnp-2845	484	2	-	-	PUNCT
fnp-2845	484	3	93	93	NUM
fnp-2845	484	4	.	.	PUNCT
fnp-2845	485	1	63	63	NUM
fnp-2845	485	2	.	.	PUNCT
fnp-2845	486	1	wang	wang	PROPN
fnp-2845	486	2	zx	zx	PROPN
fnp-2845	486	3	,	,	PUNCT
fnp-2845	486	4	tan	tan	PROPN
fnp-2845	486	5	l	l	PROPN
fnp-2845	486	6	,	,	PUNCT
fnp-2845	486	7	liu	liu	PROPN
fnp-2845	486	8	j	j	PROPN
fnp-2845	486	9	,	,	PUNCT
fnp-2845	486	10	yu	yu	PROPN
fnp-2845	486	11	jt	jt	PROPN
fnp-2845	486	12	.	.	PUNCT
fnp-2845	487	1	the	the	DET
fnp-2845	487	2	essential	essential	ADJ
fnp-2845	487	3	role	role	NOUN
fnp-2845	487	4	of	of	ADP
fnp-2845	487	5	soluble	soluble	ADJ
fnp-2845	487	6	aβ	aβ	NOUN
fnp-2845	487	7	oligomers	oligomer	NOUN
fnp-2845	487	8	in	in	ADP
fnp-2845	487	9	alzheimer	alzheimer	PROPN
fnp-2845	487	10	's	's	PART
fnp-2845	487	11	disease	disease	NOUN
fnp-2845	487	12	.	.	PUNCT
fnp-2845	488	1	mol	mol	ADP
fnp-2845	488	2	neurobiol	neurobiol	NOUN
fnp-2845	488	3	.	.	PUNCT
fnp-2845	489	1	2016;53(3):1905	2016;53(3):1905	NUM
fnp-2845	489	2	-	-	SYM
fnp-2845	489	3	24	24	NUM
fnp-2845	489	4	.	.	PUNCT
fnp-2845	489	5	64	64	NUM
fnp-2845	489	6	.	.	PUNCT
fnp-2845	490	1	minett	minett	PROPN
fnp-2845	490	2	t	t	PROPN
fnp-2845	490	3	,	,	PUNCT
fnp-2845	490	4	classey	classey	PROPN
fnp-2845	490	5	j	j	PROPN
fnp-2845	490	6	,	,	PUNCT
fnp-2845	490	7	matthews	matthews	PROPN
fnp-2845	490	8	fe	fe	PROPN
fnp-2845	490	9	,	,	PUNCT
fnp-2845	490	10	fahrenhold	fahrenhold	PROPN
fnp-2845	490	11	m	m	PROPN
fnp-2845	490	12	,	,	PUNCT
fnp-2845	490	13	taga	taga	PROPN
fnp-2845	490	14	m	m	PROPN
fnp-2845	490	15	,	,	PUNCT
fnp-2845	490	16	brayne	brayne	PROPN
fnp-2845	490	17	c	c	PROPN
fnp-2845	490	18	,	,	PUNCT
fnp-2845	490	19	et	et	PROPN
fnp-2845	490	20	al	al	PROPN
fnp-2845	490	21	.	.	PROPN
fnp-2845	490	22	microglial	microglial	ADJ
fnp-2845	490	23	immunophenotype	immunophenotype	NOUN
fnp-2845	490	24	in	in	ADP
fnp-2845	490	25	dementia	dementia	NOUN
fnp-2845	490	26	with	with	ADP
fnp-2845	490	27	alzheimer	alzheimer	PROPN
fnp-2845	490	28	's	's	PART
fnp-2845	490	29	pathology	pathology	NOUN
fnp-2845	490	30	.	.	PUNCT
fnp-2845	491	1	j	j	PROPN
fnp-2845	491	2	neuroinflammation	neuroinflammation	PROPN
fnp-2845	491	3	.	.	PUNCT
fnp-2845	492	1	2016;13(1):135	2016;13(1):135	NOUN
fnp-2845	492	2	.	.	PUNCT
fnp-2845	493	1	65	65	NUM
fnp-2845	493	2	.	.	PUNCT
fnp-2845	494	1	streit	streit	PROPN
fnp-2845	494	2	wj	wj	PROPN
fnp-2845	494	3	,	,	PUNCT
fnp-2845	494	4	khoshbouei	khoshbouei	PROPN
fnp-2845	494	5	h	h	PROPN
fnp-2845	494	6	,	,	PUNCT
fnp-2845	494	7	bechmann	bechmann	PROPN
fnp-2845	494	8	i.	i.	PROPN
fnp-2845	494	9	dystrophic	dystrophic	PROPN
fnp-2845	494	10	microglia	microglia	NOUN
fnp-2845	494	11	in	in	ADP
fnp-2845	494	12	late	late	ADJ
fnp-2845	494	13	-	-	PUNCT
fnp-2845	494	14	onset	onset	NOUN
fnp-2845	494	15	alzheimer	alzheimer	NOUN
fnp-2845	494	16	's	's	PART
fnp-2845	494	17	disease	disease	NOUN
fnp-2845	494	18	.	.	PUNCT
fnp-2845	495	1	glia	glia	PROPN
fnp-2845	495	2	.	.	PUNCT
fnp-2845	496	1	2020;68(4):845	2020;68(4):845	NUM
fnp-2845	496	2	-	-	SYM
fnp-2845	496	3	54	54	NUM
fnp-2845	496	4	.	.	PUNCT
fnp-2845	497	1	66	66	NUM
fnp-2845	497	2	.	.	PUNCT
fnp-2845	498	1	navarro	navarro	PROPN
fnp-2845	498	2	v	v	PROPN
fnp-2845	498	3	,	,	PUNCT
fnp-2845	498	4	sanchez	sanchez	NOUN
fnp-2845	498	5	-	-	PUNCT
fnp-2845	498	6	mejias	mejias	PROPN
fnp-2845	498	7	e	e	NOUN
fnp-2845	498	8	,	,	PUNCT
fnp-2845	498	9	jimenez	jimenez	PROPN
fnp-2845	498	10	s	s	PROPN
fnp-2845	498	11	,	,	PUNCT
fnp-2845	498	12	muñoz	muñoz	PROPN
fnp-2845	498	13	-	-	PUNCT
fnp-2845	498	14	castro	castro	PROPN
fnp-2845	498	15	c	c	PROPN
fnp-2845	498	16	,	,	PUNCT
fnp-2845	498	17	sanchez	sanchez	NOUN
fnp-2845	498	18	-	-	PUNCT
fnp-2845	498	19	varo	varo	PROPN
fnp-2845	498	20	r	r	PROPN
fnp-2845	498	21	,	,	PUNCT
fnp-2845	498	22	davila	davila	PROPN
fnp-2845	498	23	jc	jc	PROPN
fnp-2845	498	24	,	,	PUNCT
fnp-2845	498	25	et	et	PROPN
fnp-2845	498	26	al	al	PROPN
fnp-2845	498	27	.	.	PUNCT
fnp-2845	499	1	microglia	microglia	PROPN
fnp-2845	499	2	in	in	ADP
fnp-2845	499	3	alzheimer	alzheimer	PROPN
fnp-2845	499	4	's	's	PART
fnp-2845	499	5	disease	disease	NOUN
fnp-2845	499	6	:	:	PUNCT
fnp-2845	500	1	activated	activate	VERB
fnp-2845	500	2	,	,	PUNCT
fnp-2845	500	3	dysfunctional	dysfunctional	ADJ
fnp-2845	500	4	or	or	CCONJ
fnp-2845	500	5	degenerative	degenerative	ADJ
fnp-2845	500	6	.	.	PUNCT
fnp-2845	501	1	front	front	ADJ
fnp-2845	501	2	aging	age	VERB
fnp-2845	501	3	neurosci	neurosci	NOUN
fnp-2845	501	4	.	.	PUNCT
fnp-2845	502	1	2018;10:140	2018;10:140	NUM
fnp-2845	502	2	.	.	PROPN
fnp-2845	502	3	67	67	NUM
fnp-2845	502	4	.	.	PUNCT
fnp-2845	503	1	iqbal	iqbal	PROPN
fnp-2845	503	2	k	k	PROPN
fnp-2845	503	3	,	,	PUNCT
fnp-2845	503	4	liu	liu	PROPN
fnp-2845	503	5	f	f	PROPN
fnp-2845	503	6	,	,	PUNCT
fnp-2845	503	7	gong	gong	PROPN
fnp-2845	503	8	cx	cx	PROPN
fnp-2845	503	9	,	,	PUNCT
fnp-2845	503	10	alonso	alonso	PROPN
fnp-2845	503	11	adel	adel	PROPN
fnp-2845	503	12	c	c	PROPN
fnp-2845	503	13	,	,	PUNCT
fnp-2845	503	14	grundke	grundke	ADJ
fnp-2845	503	15	-	-	PUNCT
fnp-2845	503	16	iqbal	iqbal	PROPN
fnp-2845	503	17	i.	i.	NOUN
fnp-2845	503	18	mechanisms	mechanism	NOUN
fnp-2845	503	19	of	of	ADP
fnp-2845	503	20	tau	tau	NOUN
fnp-2845	503	21	-	-	PUNCT
fnp-2845	503	22	induced	induce	VERB
fnp-2845	503	23	neurodegeneration	neurodegeneration	NOUN
fnp-2845	503	24	.	.	PUNCT
fnp-2845	504	1	acta	acta	PROPN
fnp-2845	504	2	neuropathol	neuropathol	PROPN
fnp-2845	504	3	.	.	PUNCT
fnp-2845	505	1	2009;118(1):53	2009;118(1):53	NUM
fnp-2845	505	2	-	-	SYM
fnp-2845	505	3	69	69	NUM
fnp-2845	505	4	.	.	PUNCT
fnp-2845	506	1	68	68	NUM
fnp-2845	506	2	.	.	X
fnp-2845	507	1	grinberg	grinberg	PROPN
fnp-2845	507	2	lt	lt	PROPN
fnp-2845	507	3	,	,	PUNCT
fnp-2845	507	4	rub	rub	PROPN
fnp-2845	507	5	u	u	PROPN
fnp-2845	507	6	,	,	PUNCT
fnp-2845	507	7	ferretti	ferretti	PROPN
fnp-2845	507	8	re	re	PROPN
fnp-2845	507	9	,	,	PUNCT
fnp-2845	507	10	nitrini	nitrini	PROPN
fnp-2845	507	11	r	r	NOUN
fnp-2845	507	12	,	,	PUNCT
fnp-2845	507	13	farfel	farfel	PROPN
fnp-2845	507	14	jm	jm	PROPN
fnp-2845	507	15	,	,	PUNCT
fnp-2845	507	16	polichiso	polichiso	PROPN
fnp-2845	507	17	l	l	PROPN
fnp-2845	507	18	,	,	PUNCT
fnp-2845	507	19	et	et	PROPN
fnp-2845	507	20	al	al	PROPN
fnp-2845	507	21	.	.	PUNCT
fnp-2845	508	1	the	the	DET
fnp-2845	508	2	dorsal	dorsal	NOUN
fnp-2845	508	3	raphe	raphe	NOUN
fnp-2845	508	4	nucleus	nucleus	PROPN
fnp-2845	508	5	shows	show	VERB
fnp-2845	508	6	phospho	phospho	ADJ
fnp-2845	508	7	-	-	PUNCT
fnp-2845	508	8	tau	tau	NOUN
fnp-2845	508	9	neurofibrillary	neurofibrillary	ADJ
fnp-2845	508	10	changes	change	NOUN
fnp-2845	508	11	before	before	ADP
fnp-2845	508	12	the	the	DET
fnp-2845	508	13	transentorhinal	transentorhinal	ADJ
fnp-2845	508	14	region	region	NOUN
fnp-2845	508	15	in	in	ADP
fnp-2845	508	16	alzheimer	alzheimer	PROPN
fnp-2845	508	17	's	's	PART
fnp-2845	508	18	disease	disease	NOUN
fnp-2845	508	19	.	.	PUNCT
fnp-2845	509	1	a	a	DET
fnp-2845	509	2	precocious	precocious	ADJ
fnp-2845	509	3	onset	onset	NOUN
fnp-2845	509	4	?	?	PUNCT
fnp-2845	510	1	neuropathol	neuropathol	NOUN
fnp-2845	510	2	appl	appl	PROPN
fnp-2845	510	3	neurobiol	neurobiol	PROPN
fnp-2845	510	4	.	.	PUNCT
fnp-2845	511	1	2009;35(4):406	2009;35(4):406	PROPN
fnp-2845	511	2	-	-	SYM
fnp-2845	511	3	16	16	NUM
fnp-2845	511	4	.	.	PUNCT
fnp-2845	512	1	69	69	NUM
fnp-2845	512	2	.	.	PUNCT
fnp-2845	513	1	felsky	felsky	PROPN
fnp-2845	513	2	d	d	PROPN
fnp-2845	513	3	,	,	PUNCT
fnp-2845	513	4	roostaei	roostaei	PROPN
fnp-2845	513	5	t	t	PROPN
fnp-2845	513	6	,	,	PUNCT
fnp-2845	513	7	nho	nho	NOUN
fnp-2845	514	1	k	k	NOUN
fnp-2845	514	2	,	,	PUNCT
fnp-2845	514	3	risacher	risacher	X
fnp-2845	514	4	sl	sl	PROPN
fnp-2845	514	5	,	,	PUNCT
fnp-2845	514	6	bradshaw	bradshaw	PROPN
fnp-2845	514	7	em	em	PRON
fnp-2845	514	8	,	,	PUNCT
fnp-2845	514	9	petyuk	petyuk	NOUN
fnp-2845	514	10	v	v	NOUN
fnp-2845	514	11	,	,	PUNCT
fnp-2845	514	12	et	et	PROPN
fnp-2845	514	13	al	al	PROPN
fnp-2845	514	14	.	.	PUNCT
fnp-2845	515	1	neuropathological	neuropathological	PROPN
fnp-2845	515	2	correlates	correlate	VERB
fnp-2845	515	3	and	and	CCONJ
fnp-2845	515	4	genetic	genetic	ADJ
fnp-2845	515	5	architecture	architecture	NOUN
fnp-2845	515	6	of	of	ADP
fnp-2845	515	7	microglial	microglial	ADJ
fnp-2845	515	8	activation	activation	NOUN
fnp-2845	515	9	in	in	ADP
fnp-2845	515	10	elderly	elderly	ADJ
fnp-2845	515	11	human	human	ADJ
fnp-2845	515	12	brain	brain	NOUN
fnp-2845	515	13	.	.	PUNCT
fnp-2845	516	1	nature	nature	NOUN
fnp-2845	516	2	communications	communication	NOUN
fnp-2845	516	3	.	.	PUNCT
fnp-2845	517	1	2019;10(1):409	2019;10(1):409	NUM
fnp-2845	517	2	.	.	PUNCT
fnp-2845	518	1	70	70	NUM
fnp-2845	518	2	.	.	PUNCT
fnp-2845	519	1	ising	ise	VERB
fnp-2845	519	2	c	c	PROPN
fnp-2845	519	3	,	,	PUNCT
fnp-2845	519	4	venegas	venegas	PROPN
fnp-2845	519	5	c	c	PROPN
fnp-2845	519	6	,	,	PUNCT
fnp-2845	519	7	zhang	zhang	PROPN
fnp-2845	519	8	s	s	PROPN
fnp-2845	519	9	,	,	PUNCT
fnp-2845	519	10	scheiblich	scheiblich	ADJ
fnp-2845	519	11	h	h	NOUN
fnp-2845	519	12	,	,	PUNCT
fnp-2845	519	13	schmidt	schmidt	PROPN
fnp-2845	519	14	sv	sv	PROPN
fnp-2845	519	15	,	,	PUNCT
fnp-2845	519	16	vieira	vieira	NOUN
fnp-2845	519	17	-	-	PUNCT
fnp-2845	519	18	saecker	saecker	NOUN
fnp-2845	519	19	a	a	PRON
fnp-2845	519	20	,	,	PUNCT
fnp-2845	519	21	et	et	PROPN
fnp-2845	519	22	al	al	PROPN
fnp-2845	519	23	.	.	PUNCT
fnp-2845	520	1	nlrp3	nlrp3	PROPN
fnp-2845	520	2	inflammasome	inflammasome	NOUN
fnp-2845	520	3	activation	activation	NOUN
fnp-2845	520	4	drives	drive	VERB
fnp-2845	520	5	tau	tau	PROPN
fnp-2845	520	6	pathology	pathology	PROPN
fnp-2845	520	7	.	.	PUNCT
fnp-2845	521	1	nature	nature	NOUN
fnp-2845	521	2	.	.	PUNCT
fnp-2845	522	1	2019;575(7784):669	2019;575(7784):669	NUM
fnp-2845	522	2	-	-	SYM
fnp-2845	522	3	73	73	NUM
fnp-2845	522	4	.	.	PUNCT
fnp-2845	523	1	71	71	NUM
fnp-2845	523	2	.	.	PUNCT
fnp-2845	524	1	vogels	vogels	PROPN
fnp-2845	524	2	t	t	PROPN
fnp-2845	524	3	,	,	PUNCT
fnp-2845	524	4	murgoci	murgoci	PROPN
fnp-2845	524	5	an	an	DET
fnp-2845	524	6	,	,	PUNCT
fnp-2845	524	7	hromadka	hromadka	NOUN
fnp-2845	524	8	t.	t.	NOUN
fnp-2845	524	9	intersection	intersection	NOUN
fnp-2845	524	10	of	of	ADP
fnp-2845	524	11	pathological	pathological	ADJ
fnp-2845	524	12	tau	tau	NOUN
fnp-2845	524	13	and	and	CCONJ
fnp-2845	524	14	microglia	microglia	NOUN
fnp-2845	524	15	at	at	ADP
fnp-2845	524	16	the	the	DET
fnp-2845	524	17	synapse	synapse	NOUN
fnp-2845	524	18	.	.	PUNCT
fnp-2845	525	1	acta	acta	PROPN
fnp-2845	525	2	neuropathologica	neuropathologica	PROPN
fnp-2845	525	3	communications	communications	PROPN
fnp-2845	525	4	.	.	PUNCT
fnp-2845	526	1	2019;7(1):109	2019;7(1):109	X
fnp-2845	526	2	.	.	PUNCT
fnp-2845	527	1	copyright	copyright	NOUN
fnp-2845	527	2	:	:	PUNCT
fnp-2845	527	3	©	©	PROPN
fnp-2845	527	4	2020	2020	NUM
fnp-2845	527	5	the	the	DET
fnp-2845	527	6	author(s	author(s	NOUN
fnp-2845	527	7	)	)	PUNCT
fnp-2845	527	8	.	.	PUNCT
fnp-2845	528	1	this	this	PRON
fnp-2845	528	2	is	be	AUX
fnp-2845	528	3	an	an	DET
fnp-2845	528	4	open	open	ADJ
fnp-2845	528	5	access	access	NOUN
fnp-2845	528	6	article	article	NOUN
fnp-2845	528	7	distributed	distribute	VERB
fnp-2845	528	8	under	under	ADP
fnp-2845	528	9	the	the	DET
fnp-2845	528	10	terms	term	NOUN
fnp-2845	528	11	of	of	ADP
fnp-2845	528	12	the	the	DET
fnp-2845	528	13	creative	creative	ADJ
fnp-2845	528	14	commons	common	NOUN
fnp-2845	528	15	attribution	attribution	NOUN
fnp-2845	528	16	4.0	4.0	NUM
fnp-2845	528	17	international	international	ADJ
fnp-2845	528	18	license	license	NOUN
fnp-2845	528	19	(	(	PUNCT
fnp-2845	528	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-2845	528	21	)	)	PUNCT
fnp-2845	528	22	,	,	PUNCT
fnp-2845	528	23	which	which	PRON
fnp-2845	528	24	permits	permit	VERB
fnp-2845	528	25	unrestricted	unrestricted	ADJ
fnp-2845	528	26	use	use	NOUN
fnp-2845	528	27	,	,	PUNCT
fnp-2845	528	28	distribution	distribution	NOUN
fnp-2845	528	29	,	,	PUNCT
fnp-2845	528	30	and	and	CCONJ
fnp-2845	528	31	reproduction	reproduction	NOUN
fnp-2845	528	32	in	in	ADP
fnp-2845	528	33	any	any	DET
fnp-2845	528	34	medium	medium	NOUN
fnp-2845	528	35	,	,	PUNCT
fnp-2845	528	36	provided	provide	VERB
fnp-2845	528	37	the	the	DET
fnp-2845	528	38	original	original	ADJ
fnp-2845	528	39	author	author	NOUN
fnp-2845	528	40	and	and	CCONJ
fnp-2845	528	41	source	source	NOUN
fnp-2845	528	42	are	be	AUX
fnp-2845	528	43	credited	credit	VERB
fnp-2845	528	44	,	,	PUNCT
fnp-2845	528	45	a	a	DET
fnp-2845	528	46	link	link	NOUN
fnp-2845	528	47	to	to	ADP
fnp-2845	528	48	the	the	DET
fnp-2845	528	49	creative	creative	ADJ
fnp-2845	528	50	commons	common	NOUN
fnp-2845	528	51	license	license	NOUN
fnp-2845	528	52	is	be	AUX
fnp-2845	528	53	provided	provide	VERB
fnp-2845	528	54	,	,	PUNCT
fnp-2845	528	55	and	and	CCONJ
fnp-2845	528	56	any	any	DET
fnp-2845	528	57	changes	change	NOUN
fnp-2845	528	58	are	be	AUX
fnp-2845	528	59	indicated	indicate	VERB
fnp-2845	528	60	.	.	PUNCT
fnp-2845	529	1	the	the	DET
fnp-2845	529	2	creative	creative	ADJ
fnp-2845	529	3	commons	common	NOUN
fnp-2845	529	4	public	public	ADJ
fnp-2845	529	5	domain	domain	NOUN
fnp-2845	529	6	dedication	dedication	NOUN
fnp-2845	529	7	waiver	waiver	NOUN
fnp-2845	529	8	(	(	PUNCT
fnp-2845	529	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-2845	529	10	)	)	PUNCT
fnp-2845	529	11	applies	apply	VERB
fnp-2845	529	12	to	to	ADP
fnp-2845	529	13	the	the	DET
fnp-2845	529	14	data	datum	NOUN
fnp-2845	529	15	made	make	VERB
fnp-2845	529	16	available	available	ADJ
fnp-2845	529	17	in	in	ADP
fnp-2845	529	18	this	this	DET
fnp-2845	529	19	article	article	NOUN
fnp-2845	529	20	,	,	PUNCT
fnp-2845	529	21	unless	unless	SCONJ
fnp-2845	529	22	otherwise	otherwise	ADV
fnp-2845	529	23	stated	state	VERB
fnp-2845	529	24	.	.	PUNCT