id	sid	tid	token	lemma	pos
fnp-2920	1	1	enteric	enteric	ADJ
fnp-2920	1	2	synucleinopathy	synucleinopathy	NOUN
fnp-2920	1	3	:	:	PUNCT
fnp-2920	1	4	from	from	ADP
fnp-2920	1	5	trendy	trendy	ADJ
fnp-2920	1	6	concept	concept	NOUN
fnp-2920	1	7	to	to	ADP
fnp-2920	1	8	real	real	ADJ
fnp-2920	1	9	entity	entity	NOUN
fnp-2920	1	10	.	.	PUNCT
fnp-2920	2	1	feel	feel	VERB
fnp-2920	2	2	free	free	ADJ
fnp-2920	2	3	to	to	PART
fnp-2920	2	4	add	add	VERB
fnp-2920	2	5	comments	comment	NOUN
fnp-2920	2	6	by	by	ADP
fnp-2920	2	7	clicking	click	VERB
fnp-2920	2	8	these	these	DET
fnp-2920	2	9	icons	icon	NOUN
fnp-2920	2	10	on	on	ADP
fnp-2920	2	11	the	the	DET
fnp-2920	2	12	sidebar	sidebar	NOUN
fnp-2920	2	13	free	free	ADJ
fnp-2920	2	14	neuropathology	neuropathology	NOUN
fnp-2920	2	15	1:26	1:26	NUM
fnp-2920	2	16	(	(	PUNCT
fnp-2920	2	17	2020	2020	NUM
fnp-2920	2	18	)	)	PUNCT
fnp-2920	2	19	opinion	opinion	NOUN
fnp-2920	2	20	piece	piece	NOUN
fnp-2920	2	21	enteric	enteric	NOUN
fnp-2920	2	22	synucleinopathy	synucleinopathy	NOUN
fnp-2920	2	23	:	:	PUNCT
fnp-2920	2	24	from	from	ADP
fnp-2920	2	25	trendy	trendy	ADJ
fnp-2920	2	26	concept	concept	NOUN
fnp-2920	2	27	to	to	ADP
fnp-2920	2	28	real	real	ADJ
fnp-2920	2	29	entity	entity	NOUN
fnp-2920	2	30	.	.	PUNCT
fnp-2920	3	1	adrien	adrien	PROPN
fnp-2920	3	2	de	de	PROPN
fnp-2920	3	3	guilhem	guilhem	PROPN
fnp-2920	3	4	de	de	X
fnp-2920	3	5	lataillade	lataillade	PROPN
fnp-2920	3	6	1,2	1,2	NUM
fnp-2920	3	7	,	,	PUNCT
fnp-2920	3	8	thibaud	thibaud	ADJ
fnp-2920	3	9	lebouvier	lebouvi	ADJ
fnp-2920	3	10	3	3	NUM
fnp-2920	3	11	,	,	PUNCT
fnp-2920	3	12	wendy	wendy	PROPN
fnp-2920	3	13	noble	noble	ADJ
fnp-2920	3	14	4	4	NUM
fnp-2920	3	15	,	,	PUNCT
fnp-2920	3	16	laurène	laurène	PROPN
fnp-2920	3	17	leclair	leclair	PROPN
fnp-2920	3	18	-	-	PUNCT
fnp-2920	3	19	visonneau	visonneau	PROPN
fnp-2920	3	20	1	1	NUM
fnp-2920	3	21	,	,	PUNCT
fnp-2920	3	22	pascal	pascal	ADJ
fnp-2920	3	23	derkinderen	derkinderen	NOUN
fnp-2920	3	24	1,2	1,2	NUM
fnp-2920	3	25	1	1	NUM
fnp-2920	3	26	université	université	X
fnp-2920	3	27	de	de	X
fnp-2920	3	28	nantes	nante	NOUN
fnp-2920	3	29	,	,	PUNCT
fnp-2920	3	30	inserm	inserm	NOUN
fnp-2920	3	31	,	,	PUNCT
fnp-2920	3	32	tens	ten	NOUN
fnp-2920	3	33	,	,	PUNCT
fnp-2920	3	34	the	the	DET
fnp-2920	3	35	enteric	enteric	ADJ
fnp-2920	3	36	nervous	nervous	ADJ
fnp-2920	3	37	system	system	NOUN
fnp-2920	3	38	in	in	ADP
fnp-2920	3	39	gut	gut	NOUN
fnp-2920	3	40	and	and	CCONJ
fnp-2920	3	41	brain	brain	NOUN
fnp-2920	3	42	diseases	disease	NOUN
fnp-2920	3	43	,	,	PUNCT
fnp-2920	3	44	imad	imad	NOUN
fnp-2920	3	45	,	,	PUNCT
fnp-2920	3	46	nantes	nante	NOUN
fnp-2920	3	47	,	,	PUNCT
fnp-2920	3	48	france	france	PROPN
fnp-2920	3	49	2	2	NUM
fnp-2920	3	50	chu	chu	PROPN
fnp-2920	3	51	nantes	nante	NOUN
fnp-2920	3	52	,	,	PUNCT
fnp-2920	3	53	department	department	NOUN
fnp-2920	3	54	of	of	ADP
fnp-2920	3	55	neurology	neurology	NOUN
fnp-2920	3	56	,	,	PUNCT
fnp-2920	3	57	nantes	nante	NOUN
fnp-2920	3	58	,	,	PUNCT
fnp-2920	3	59	f-44093	f-44093	PROPN
fnp-2920	3	60	,	,	PUNCT
fnp-2920	3	61	france	france	PROPN
fnp-2920	3	62	3	3	NUM
fnp-2920	3	63	univ	univ	PROPN
fnp-2920	3	64	.	.	PUNCT
fnp-2920	4	1	lille	lille	PROPN
fnp-2920	4	2	,	,	PUNCT
fnp-2920	4	3	inserm	inserm	NOUN
fnp-2920	4	4	urm_s1172	urm_s1172	NOUN
fnp-2920	4	5	,	,	PUNCT
fnp-2920	4	6	chu	chu	PROPN
fnp-2920	4	7	lille	lille	PROPN
fnp-2920	4	8	,	,	PUNCT
fnp-2920	4	9	distalz	distalz	ADJ
fnp-2920	4	10	,	,	PUNCT
fnp-2920	4	11	licend	licend	INTJ
fnp-2920	4	12	,	,	PUNCT
fnp-2920	4	13	f-59000	f-59000	PROPN
fnp-2920	4	14	lille	lille	PROPN
fnp-2920	4	15	,	,	PUNCT
fnp-2920	4	16	france	france	PROPN
fnp-2920	4	17	4	4	NUM
fnp-2920	4	18	king	king	PROPN
fnp-2920	4	19	’s	’s	PART
fnp-2920	4	20	college	college	PROPN
fnp-2920	4	21	london	london	PROPN
fnp-2920	4	22	,	,	PUNCT
fnp-2920	4	23	institute	institute	PROPN
fnp-2920	4	24	of	of	ADP
fnp-2920	4	25	psychiatry	psychiatry	NOUN
fnp-2920	4	26	,	,	PUNCT
fnp-2920	4	27	psychology	psychology	NOUN
fnp-2920	4	28	and	and	CCONJ
fnp-2920	4	29	neuroscience	neuroscience	NOUN
fnp-2920	4	30	,	,	PUNCT
fnp-2920	4	31	department	department	NOUN
fnp-2920	4	32	of	of	ADP
fnp-2920	4	33	basic	basic	ADJ
fnp-2920	4	34	and	and	CCONJ
fnp-2920	4	35	clinical	clinical	ADJ
fnp-2920	4	36	neuroscience	neuroscience	NOUN
fnp-2920	4	37	,	,	PUNCT
fnp-2920	4	38	maurice	maurice	NOUN
fnp-2920	4	39	wohl	wohl	VERB
fnp-2920	4	40	clinical	clinical	ADJ
fnp-2920	4	41	neuroscience	neuroscience	PROPN
fnp-2920	4	42	institute	institute	NOUN
fnp-2920	4	43	,	,	PUNCT
fnp-2920	4	44	5	5	NUM
fnp-2920	4	45	cutcombe	cutcombe	NOUN
fnp-2920	4	46	road	road	NOUN
fnp-2920	4	47	,	,	PUNCT
fnp-2920	4	48	camberwell	camberwell	PROPN
fnp-2920	4	49	,	,	PUNCT
fnp-2920	4	50	london	london	PROPN
fnp-2920	4	51	.	.	PUNCT
fnp-2920	5	1	se5	se5	PROPN
fnp-2920	5	2	9rx	9rx	NOUN
fnp-2920	5	3	,	,	PUNCT
fnp-2920	5	4	uk	uk	PROPN
fnp-2920	5	5	corresponding	corresponding	ADJ
fnp-2920	5	6	author	author	NOUN
fnp-2920	5	7	:	:	PUNCT
fnp-2920	5	8	pascal	pascal	PROPN
fnp-2920	5	9	derkinderen	derkinderen	PROPN
fnp-2920	5	10	·	·	PUNCT
fnp-2920	5	11	inserm	inserm	NOUN
fnp-2920	5	12	u1235	u1235	PROPN
fnp-2920	5	13	nantes	nante	NOUN
fnp-2920	5	14	·	·	PUNCT
fnp-2920	5	15	1	1	NUM
fnp-2920	5	16	rue	rue	X
fnp-2920	5	17	gaston	gaston	PROPN
fnp-2920	5	18	veil	veil	PROPN
fnp-2920	5	19	·	·	PUNCT
fnp-2920	5	20	44035	44035	NUM
fnp-2920	5	21	nantes	nante	VERB
fnp-2920	5	22	·	·	PUNCT
fnp-2920	5	23	france	france	PROPN
fnp-2920	5	24	·	·	PUNCT
fnp-2920	6	1	tel	tel	ADP
fnp-2920	6	2	:	:	PUNCT
fnp-2920	6	3	+33(0)240165202	+33(0)240165202	PROPN
fnp-2920	6	4	·	·	PUNCT
fnp-2920	6	5	fax	fax	NOUN
fnp-2920	6	6	:	:	PUNCT
fnp-2920	6	7	+33(0)240165203	+33(0)240165203	PROPN
fnp-2920	6	8	pascal.derkinderen@chu-nantes.fr	pascal.derkinderen@chu-nantes.fr	PROPN
fnp-2920	6	9	submitted	submit	VERB
fnp-2920	6	10	:	:	PUNCT
fnp-2920	6	11	29	29	NUM
fnp-2920	6	12	july	july	PROPN
fnp-2920	6	13	2020	2020	NUM
fnp-2920	6	14	accepted	accept	VERB
fnp-2920	6	15	:	:	PUNCT
fnp-2920	6	16	23	23	NUM
fnp-2920	6	17	august	august	PROPN
fnp-2920	6	18	2020	2020	NUM
fnp-2920	6	19	copyedited	copyedit	VERB
fnp-2920	6	20	by	by	ADP
fnp-2920	6	21	:	:	PUNCT
fnp-2920	7	1	aivi	aivi	PROPN
fnp-2920	7	2	t.	t.	PROPN
fnp-2920	7	3	nguyen	nguyen	PROPN
fnp-2920	7	4	published	publish	VERB
fnp-2920	7	5	:	:	PUNCT
fnp-2920	7	6	28	28	NUM
fnp-2920	7	7	august	august	NOUN
fnp-2920	7	8	2020	2020	NUM
fnp-2920	7	9	https://doi.org/10.17879/freeneuropathology-2020-2920	https://doi.org/10.17879/freeneuropathology-2020-2920	NOUN
fnp-2920	7	10	keywords	keyword	NOUN
fnp-2920	7	11	:	:	PUNCT
fnp-2920	7	12	synucleinopathies	synucleinopathie	NOUN
fnp-2920	7	13	,	,	PUNCT
fnp-2920	7	14	tauopathies	tauopathie	NOUN
fnp-2920	7	15	,	,	PUNCT
fnp-2920	7	16	enteric	enteric	ADJ
fnp-2920	7	17	nervous	nervous	ADJ
fnp-2920	7	18	system	system	NOUN
fnp-2920	7	19	,	,	PUNCT
fnp-2920	7	20	aggregates	aggregate	NOUN
fnp-2920	7	21	,	,	PUNCT
fnp-2920	7	22	alpha	alpha	NOUN
fnp-2920	7	23	-	-	PUNCT
fnp-2920	7	24	synuclein	synuclein	NOUN
fnp-2920	7	25	,	,	PUNCT
fnp-2920	7	26	parkinson	parkinson	NOUN
fnp-2920	7	27	’s	’s	PART
fnp-2920	7	28	disease	disease	NOUN
fnp-2920	7	29	abstract	abstract	NOUN
fnp-2920	7	30	an	an	DET
fnp-2920	7	31	accumulating	accumulate	VERB
fnp-2920	7	32	body	body	NOUN
fnp-2920	7	33	of	of	ADP
fnp-2920	7	34	literature	literature	NOUN
fnp-2920	7	35	has	have	AUX
fnp-2920	7	36	emerged	emerge	VERB
fnp-2920	7	37	in	in	ADP
fnp-2920	7	38	the	the	DET
fnp-2920	7	39	past	past	ADJ
fnp-2920	7	40	25	25	NUM
fnp-2920	7	41	years	year	NOUN
fnp-2920	7	42	to	to	PART
fnp-2920	7	43	show	show	VERB
fnp-2920	7	44	that	that	DET
fnp-2920	7	45	parkinson	parkinson	NOUN
fnp-2920	7	46	’s	’s	PART
fnp-2920	7	47	disease	disease	NOUN
fnp-2920	7	48	(	(	PUNCT
fnp-2920	7	49	pd	pd	NOUN
fnp-2920	7	50	)	)	PUNCT
fnp-2920	7	51	is	be	AUX
fnp-2920	7	52	not	not	PART
fnp-2920	7	53	only	only	ADV
fnp-2920	7	54	a	a	DET
fnp-2920	7	55	disorder	disorder	NOUN
fnp-2920	7	56	of	of	ADP
fnp-2920	7	57	the	the	DET
fnp-2920	7	58	brain	brain	NOUN
fnp-2920	7	59	but	but	CCONJ
fnp-2920	7	60	also	also	ADV
fnp-2920	7	61	of	of	ADP
fnp-2920	7	62	the	the	DET
fnp-2920	7	63	gastrointestinal	gastrointestinal	ADJ
fnp-2920	7	64	tract	tract	NOUN
fnp-2920	7	65	and	and	CCONJ
fnp-2920	7	66	more	more	ADV
fnp-2920	7	67	generally	generally	ADV
fnp-2920	7	68	of	of	ADP
fnp-2920	7	69	the	the	DET
fnp-2920	7	70	gut	gut	NOUN
fnp-2920	7	71	-	-	PUNCT
fnp-2920	7	72	brain	brain	NOUN
fnp-2920	7	73	axis	axis	NOUN
fnp-2920	7	74	.	.	PUNCT
fnp-2920	8	1	gastrointestinal	gastrointestinal	ADJ
fnp-2920	8	2	symptoms	symptom	NOUN
fnp-2920	8	3	occur	occur	VERB
fnp-2920	8	4	in	in	ADP
fnp-2920	8	5	almost	almost	ADV
fnp-2920	8	6	every	every	PRON
fnp-2920	8	7	pd	pd	NOUN
fnp-2920	8	8	patient	patient	NOUN
fnp-2920	8	9	at	at	ADP
fnp-2920	8	10	some	some	DET
fnp-2920	8	11	point	point	NOUN
fnp-2920	8	12	and	and	CCONJ
fnp-2920	8	13	in	in	ADP
fnp-2920	8	14	nearly	nearly	ADV
fnp-2920	8	15	every	every	PRON
fnp-2920	8	16	case	case	NOUN
fnp-2920	8	17	examined	examine	VERB
fnp-2920	8	18	pathologically	pathologically	ADV
fnp-2920	8	19	autopsy	autopsy	ADJ
fnp-2920	8	20	studies	study	NOUN
fnp-2920	8	21	find	find	VERB
fnp-2920	8	22	alpha	alpha	NOUN
fnp-2920	8	23	-	-	PUNCT
fnp-2920	8	24	synuclein	synuclein	NOUN
fnp-2920	8	25	deposits	deposit	NOUN
fnp-2920	8	26	,	,	PUNCT
fnp-2920	8	27	the	the	DET
fnp-2920	8	28	pathological	pathological	ADJ
fnp-2920	8	29	hallmarks	hallmark	NOUN
fnp-2920	8	30	of	of	ADP
fnp-2920	8	31	pd	pd	PROPN
fnp-2920	8	32	,	,	PUNCT
fnp-2920	8	33	in	in	ADP
fnp-2920	8	34	the	the	DET
fnp-2920	8	35	enteric	enteric	ADJ
fnp-2920	8	36	nervous	nervous	ADJ
fnp-2920	8	37	system	system	NOUN
fnp-2920	8	38	.	.	PUNCT
fnp-2920	9	1	this	this	DET
fnp-2920	9	2	concept	concept	NOUN
fnp-2920	9	3	of	of	ADP
fnp-2920	9	4	‘	'	PUNCT
fnp-2920	9	5	enteric	enteric	ADJ
fnp-2920	9	6	synucleinopathy	synucleinopathy	NOUN
fnp-2920	9	7	’	'	PUNCT
fnp-2920	9	8	led	lead	VERB
fnp-2920	9	9	to	to	ADP
fnp-2920	9	10	the	the	DET
fnp-2920	9	11	hypothesis	hypothesis	NOUN
fnp-2920	9	12	that	that	PRON
fnp-2920	9	13	the	the	DET
fnp-2920	9	14	enteric	enteric	ADJ
fnp-2920	9	15	nervous	nervous	ADJ
fnp-2920	9	16	system	system	NOUN
fnp-2920	9	17	might	might	AUX
fnp-2920	9	18	play	play	VERB
fnp-2920	9	19	a	a	DET
fnp-2920	9	20	pivotal	pivotal	ADJ
fnp-2920	9	21	role	role	NOUN
fnp-2920	9	22	in	in	ADP
fnp-2920	9	23	the	the	DET
fnp-2920	9	24	initiation	initiation	NOUN
fnp-2920	9	25	and	and	CCONJ
fnp-2920	9	26	spreading	spread	VERB
fnp-2920	9	27	of	of	ADP
fnp-2920	9	28	pd	pd	PROPN
fnp-2920	9	29	.	.	PUNCT
fnp-2920	10	1	although	although	SCONJ
fnp-2920	10	2	this	this	DET
fnp-2920	10	3	hypothesis	hypothesis	NOUN
fnp-2920	10	4	opens	open	VERB
fnp-2920	10	5	up	up	ADP
fnp-2920	10	6	interesting	interesting	ADJ
fnp-2920	10	7	perspectives	perspective	NOUN
fnp-2920	10	8	on	on	ADP
fnp-2920	10	9	the	the	DET
fnp-2920	10	10	pathogenesis	pathogenesis	NOUN
fnp-2920	10	11	of	of	ADP
fnp-2920	10	12	neurodegenerative	neurodegenerative	ADJ
fnp-2920	10	13	disorders	disorder	NOUN
fnp-2920	10	14	,	,	PUNCT
fnp-2920	10	15	some	some	DET
fnp-2920	10	16	important	important	ADJ
fnp-2920	10	17	questions	question	NOUN
fnp-2920	10	18	are	be	AUX
fnp-2920	10	19	still	still	ADV
fnp-2920	10	20	pending	pende	VERB
fnp-2920	10	21	.	.	PUNCT
fnp-2920	11	1	the	the	DET
fnp-2920	11	2	present	present	ADJ
fnp-2920	11	3	opinion	opinion	NOUN
fnp-2920	11	4	paper	paper	NOUN
fnp-2920	11	5	describes	describe	VERB
fnp-2920	11	6	and	and	CCONJ
fnp-2920	11	7	compares	compare	VERB
fnp-2920	11	8	the	the	DET
fnp-2920	11	9	physiological	physiological	ADJ
fnp-2920	11	10	and	and	CCONJ
fnp-2920	11	11	pathophysiological	pathophysiological	ADJ
fnp-2920	11	12	properties	property	NOUN
fnp-2920	11	13	of	of	ADP
fnp-2920	11	14	alpha	alpha	NOUN
fnp-2920	11	15	-	-	PUNCT
fnp-2920	11	16	synuclein	synuclein	NOUN
fnp-2920	11	17	in	in	ADP
fnp-2920	11	18	the	the	DET
fnp-2920	11	19	brain	brain	NOUN
fnp-2920	11	20	and	and	CCONJ
fnp-2920	11	21	the	the	DET
fnp-2920	11	22	enteric	enteric	ADJ
fnp-2920	11	23	nervous	nervous	ADJ
fnp-2920	11	24	system	system	NOUN
fnp-2920	11	25	.	.	PUNCT
fnp-2920	12	1	we	we	PRON
fnp-2920	12	2	conclude	conclude	VERB
fnp-2920	12	3	that	that	SCONJ
fnp-2920	12	4	the	the	DET
fnp-2920	12	5	existing	exist	VERB
fnp-2920	12	6	data	datum	NOUN
fnp-2920	12	7	supports	support	VERB
fnp-2920	12	8	the	the	DET
fnp-2920	12	9	existence	existence	NOUN
fnp-2920	12	10	of	of	ADP
fnp-2920	12	11	pathological	pathological	ADJ
fnp-2920	12	12	alpha	alpha	NOUN
fnp-2920	12	13	-	-	PUNCT
fnp-2920	12	14	synuclein	synuclein	NOUN
fnp-2920	12	15	species	specie	NOUN
fnp-2920	12	16	in	in	ADP
fnp-2920	12	17	the	the	DET
fnp-2920	12	18	gut	gut	NOUN
fnp-2920	12	19	in	in	ADP
fnp-2920	12	20	pd	pd	PROPN
fnp-2920	12	21	.	.	PUNCT
fnp-2920	13	1	we	we	PRON
fnp-2920	13	2	also	also	ADV
fnp-2920	13	3	discuss	discuss	VERB
fnp-2920	13	4	if	if	SCONJ
fnp-2920	13	5	gut	gut	NOUN
fnp-2920	13	6	-	-	PUNCT
fnp-2920	13	7	brain	brain	NOUN
fnp-2920	13	8	interactions	interaction	NOUN
fnp-2920	13	9	are	be	AUX
fnp-2920	13	10	important	important	ADJ
fnp-2920	13	11	in	in	ADP
fnp-2920	13	12	other	other	ADJ
fnp-2920	13	13	neurodegenerative	neurodegenerative	ADJ
fnp-2920	13	14	disorders	disorder	NOUN
fnp-2920	13	15	.	.	PUNCT
fnp-2920	14	1	abbreviations	abbreviation	NOUN
fnp-2920	14	2	ad	ad	PROPN
fnp-2920	14	3	alzheimer	alzheimer	PROPN
fnp-2920	14	4	’s	’s	PART
fnp-2920	14	5	disease	disease	NOUN
fnp-2920	14	6	,	,	PUNCT
fnp-2920	14	7	ens	en	NOUN
fnp-2920	14	8	enteric	enteric	ADJ
fnp-2920	14	9	nervous	nervous	ADJ
fnp-2920	14	10	system	system	NOUN
fnp-2920	14	11	,	,	PUNCT
fnp-2920	14	12	gi	gi	VERB
fnp-2920	14	13	gastrointestinal	gastrointestinal	ADJ
fnp-2920	14	14	,	,	PUNCT
fnp-2920	14	15	lb	lb	DET
fnp-2920	14	16	lewy	lewy	PROPN
fnp-2920	14	17	bodies	body	NOUN
fnp-2920	14	18	,	,	PUNCT
fnp-2920	14	19	ln	ln	PROPN
fnp-2920	14	20	lewy	lewy	PROPN
fnp-2920	14	21	neurites	neurites	PROPN
fnp-2920	14	22	,	,	PUNCT
fnp-2920	14	23	pd	pd	PROPN
fnp-2920	14	24	parkinson	parkinson	NOUN
fnp-2920	14	25	’s	’s	PART
fnp-2920	14	26	disease	disease	NOUN
fnp-2920	14	27	,	,	PUNCT
fnp-2920	14	28	pmca	pmca	NOUN
fnp-2920	14	29	protein	protein	NOUN
fnp-2920	14	30	misfolding	misfolde	VERB
fnp-2920	14	31	cyclic	cyclic	ADJ
fnp-2920	14	32	amplification	amplification	NOUN
fnp-2920	14	33	,	,	PUNCT
fnp-2920	14	34	psp	psp	NOUN
fnp-2920	14	35	progressive	progressive	ADJ
fnp-2920	14	36	supranuclear	supranuclear	ADJ
fnp-2920	14	37	palsy	palsy	ADJ
fnp-2920	14	38	the	the	DET
fnp-2920	14	39	enteric	enteric	ADJ
fnp-2920	14	40	nervous	nervous	ADJ
fnp-2920	14	41	system	system	NOUN
fnp-2920	14	42	(	(	PUNCT
fnp-2920	14	43	ens	ens	PROPN
fnp-2920	14	44	)	)	PUNCT
fnp-2920	14	45	is	be	AUX
fnp-2920	14	46	an	an	DET
fnp-2920	14	47	intricate	intricate	ADJ
fnp-2920	14	48	neural	neural	ADJ
fnp-2920	14	49	network	network	NOUN
fnp-2920	14	50	embedded	embed	VERB
fnp-2920	14	51	within	within	ADP
fnp-2920	14	52	the	the	DET
fnp-2920	14	53	gastrointestinal	gastrointestinal	ADJ
fnp-2920	14	54	(	(	PUNCT
fnp-2920	14	55	gi	gi	NOUN
fnp-2920	14	56	)	)	PUNCT
fnp-2920	14	57	tract	tract	NOUN
fnp-2920	14	58	and	and	CCONJ
fnp-2920	14	59	distributed	distribute	VERB
fnp-2920	14	60	from	from	ADP
fnp-2920	14	61	the	the	DET
fnp-2920	14	62	lower	low	ADJ
fnp-2920	14	63	oesophagus	oesophagus	NOUN
fnp-2920	14	64	to	to	ADP
fnp-2920	14	65	the	the	DET
fnp-2920	14	66	rectum	rectum	NOUN
fnp-2920	14	67	.	.	PUNCT
fnp-2920	15	1	compared	compare	VERB
fnp-2920	15	2	to	to	ADP
fnp-2920	15	3	other	other	ADJ
fnp-2920	15	4	components	component	NOUN
fnp-2920	15	5	of	of	ADP
fnp-2920	15	6	the	the	DET
fnp-2920	15	7	peripheral	peripheral	ADJ
fnp-2920	15	8	nervous	nervous	ADJ
fnp-2920	15	9	system	system	NOUN
fnp-2920	15	10	,	,	PUNCT
fnp-2920	15	11	the	the	DET
fnp-2920	15	12	ens	ens	NOUN
fnp-2920	15	13	shows	show	VERB
fnp-2920	15	14	some	some	DET
fnp-2920	15	15	unique	unique	ADJ
fnp-2920	15	16	features	feature	NOUN
fnp-2920	15	17	that	that	PRON
fnp-2920	15	18	closely	closely	ADV
fnp-2920	15	19	resemble	resemble	VERB
fnp-2920	15	20	the	the	DET
fnp-2920	15	21	cns	cns	NOUN
fnp-2920	15	22	and	and	CCONJ
fnp-2920	15	23	therefore	therefore	ADV
fnp-2920	15	24	it	it	PRON
fnp-2920	15	25	is	be	AUX
fnp-2920	15	26	sometimes	sometimes	ADV
fnp-2920	15	27	referred	refer	VERB
fnp-2920	15	28	to	to	ADP
fnp-2920	15	29	as	as	ADP
fnp-2920	15	30	‘	'	PUNCT
fnp-2920	15	31	the	the	DET
fnp-2920	15	32	brain	brain	NOUN
fnp-2920	15	33	-	-	PUNCT
fnp-2920	15	34	in	in	ADP
fnp-2920	15	35	-	-	PUNCT
fnp-2920	15	36	the	the	DET
fnp-2920	15	37	-	-	PUNCT
fnp-2920	15	38	gut	gut	NOUN
fnp-2920	15	39	’	'	PUNCT
fnp-2920	15	40	or	or	CCONJ
fnp-2920	15	41	the	the	DET
fnp-2920	15	42	‘	'	PUNCT
fnp-2920	15	43	second	second	ADJ
fnp-2920	15	44	brain	brain	NOUN
fnp-2920	15	45	’	'	PUNCT
fnp-2920	16	1	[	[	X
fnp-2920	16	2	1	1	NUM
fnp-2920	16	3	]	]	PUNCT
fnp-2920	16	4	(	(	PUNCT
fnp-2920	16	5	figure	figure	NOUN
fnp-2920	16	6	1	1	NUM
fnp-2920	16	7	)	)	PUNCT
fnp-2920	16	8	.	.	PUNCT
fnp-2920	17	1	this	this	DET
fnp-2920	17	2	close	close	ADJ
fnp-2920	17	3	homology	homology	NOUN
fnp-2920	17	4	between	between	ADP
fnp-2920	17	5	the	the	DET
fnp-2920	17	6	cns	cns	NOUN
fnp-2920	17	7	and	and	CCONJ
fnp-2920	17	8	ens	ens	PROPN
fnp-2920	17	9	suggests	suggest	VERB
fnp-2920	17	10	that	that	SCONJ
fnp-2920	17	11	a	a	DET
fnp-2920	17	12	disease	disease	NOUN
fnp-2920	17	13	process	process	NOUN
fnp-2920	17	14	affecting	affect	VERB
fnp-2920	17	15	the	the	DET
fnp-2920	17	16	cns	cns	NOUN
fnp-2920	17	17	could	could	AUX
fnp-2920	17	18	also	also	ADV
fnp-2920	17	19	involve	involve	VERB
fnp-2920	17	20	its	its	PRON
fnp-2920	17	21	enteric	enteric	ADJ
fnp-2920	17	22	counterpart	counterpart	NOUN
fnp-2920	17	23	.	.	PUNCT
fnp-2920	18	1	parkinson	parkinson	NOUN
fnp-2920	18	2	’s	’s	PART
fnp-2920	18	3	disease	disease	NOUN
fnp-2920	18	4	(	(	PUNCT
fnp-2920	18	5	pd	pd	NOUN
fnp-2920	18	6	)	)	PUNCT
fnp-2920	18	7	is	be	AUX
fnp-2920	18	8	the	the	DET
fnp-2920	18	9	best	good	ADJ
fnp-2920	18	10	example	example	NOUN
fnp-2920	18	11	of	of	ADP
fnp-2920	18	12	this	this	DET
fnp-2920	18	13	assumption	assumption	NOUN
fnp-2920	18	14	.	.	PUNCT
fnp-2920	19	1	pd	pd	PROPN
fnp-2920	19	2	is	be	AUX
fnp-2920	19	3	the	the	DET
fnp-2920	19	4	most	most	ADV
fnp-2920	19	5	common	common	ADJ
fnp-2920	19	6	synucleinopathy	synucleinopathy	NOUN
fnp-2920	19	7	(	(	PUNCT
fnp-2920	19	8	or	or	CCONJ
fnp-2920	19	9	synuclein	synuclein	VERB
fnp-2920	19	10	proteinopathy	proteinopathy	ADJ
fnp-2920	19	11	)	)	PUNCT
fnp-2920	19	12	,	,	PUNCT
fnp-2920	19	13	a	a	DET
fnp-2920	19	14	group	group	NOUN
fnp-2920	19	15	of	of	ADP
fnp-2920	19	16	neurodegenerative	neurodegenerative	ADJ
fnp-2920	19	17	disorders	disorder	NOUN
fnp-2920	19	18	characterized	characterize	VERB
fnp-2920	19	19	by	by	ADP
fnp-2920	19	20	a	a	DET
fnp-2920	19	21	common	common	ADJ
fnp-2920	19	22	pathological	pathological	ADJ
fnp-2920	19	23	lesion	lesion	NOUN
fnp-2920	19	24	composed	compose	VERB
fnp-2920	19	25	of	of	ADP
fnp-2920	19	26	aggregates	aggregate	NOUN
fnp-2920	19	27	of	of	ADP
fnp-2920	19	28	alpha	alpha	NOUN
fnp-2920	19	29	-	-	PUNCT
fnp-2920	19	30	synuclein	synuclein	NOUN
fnp-2920	19	31	in	in	ADP
fnp-2920	19	32	selectively	selectively	ADV
fnp-2920	19	33	vulnerable	vulnerable	ADJ
fnp-2920	19	34	neuron	neuron	NOUN
fnp-2920	19	35	populations	population	NOUN
fnp-2920	19	36	in	in	ADP
fnp-2920	19	37	the	the	DET
fnp-2920	19	38	cns	cns	NOUN
fnp-2920	20	1	[	[	X
fnp-2920	20	2	2	2	NUM
fnp-2920	20	3	]	]	PUNCT
fnp-2920	20	4	.	.	PUNCT
fnp-2920	21	1	although	although	SCONJ
fnp-2920	21	2	pd	pd	PROPN
fnp-2920	21	3	has	have	AUX
fnp-2920	21	4	traditionally	traditionally	ADV
fnp-2920	21	5	been	be	AUX
fnp-2920	21	6	considered	consider	VERB
fnp-2920	21	7	a	a	DET
fnp-2920	21	8	disease	disease	NOUN
fnp-2920	21	9	of	of	ADP
fnp-2920	21	10	dopaminergic	dopaminergic	ADJ
fnp-2920	21	11	neurons	neuron	NOUN
fnp-2920	21	12	in	in	ADP
fnp-2920	21	13	the	the	DET
fnp-2920	21	14	substantia	substantia	NOUN
fnp-2920	21	15	nigra	nigra	NOUN
fnp-2920	21	16	,	,	PUNCT
fnp-2920	21	17	analyses	analysis	NOUN
fnp-2920	21	18	of	of	ADP
fnp-2920	21	19	gi	gi	NOUN
fnp-2920	21	20	samples	sample	NOUN
fnp-2920	21	21	from	from	ADP
fnp-2920	21	22	pd	pd	PROPN
fnp-2920	21	23	patients	patient	NOUN
fnp-2920	21	24	have	have	AUX
fnp-2920	21	25	consistently	consistently	ADV
fnp-2920	21	26	found	find	VERB
fnp-2920	21	27	neural	neural	ADJ
fnp-2920	21	28	pathology	pathology	NOUN
fnp-2920	21	29	,	,	PUNCT
fnp-2920	21	30	with	with	SCONJ
fnp-2920	21	31	the	the	DET
fnp-2920	21	32	presence	presence	NOUN
fnp-2920	21	33	of	of	ADP
fnp-2920	21	34	alpha	alpha	NOUN
fnp-2920	21	35	-	-	PUNCT
fnp-2920	21	36	synuclein	synuclein	NOUN
fnp-2920	21	37	deposits	deposit	NOUN
fnp-2920	21	38	being	be	AUX
fnp-2920	21	39	detected	detect	VERB
fnp-2920	21	40	in	in	ADP
fnp-2920	21	41	the	the	DET
fnp-2920	21	42	ens	ens	NOUN
fnp-2920	21	43	in	in	ADP
fnp-2920	21	44	nearly	nearly	ADV
fnp-2920	21	45	every	every	PRON
fnp-2920	21	46	pd	pd	NOUN
fnp-2920	21	47	patient	patient	NOUN
fnp-2920	21	48	examined	examine	VERB
fnp-2920	21	49	[	[	X
fnp-2920	21	50	3–11	3–11	NOUN
fnp-2920	21	51	]	]	PUNCT
fnp-2920	21	52	.	.	PUNCT
fnp-2920	22	1	this	this	PRON
fnp-2920	22	2	has	have	AUX
fnp-2920	22	3	led	lead	VERB
fnp-2920	22	4	to	to	ADP
fnp-2920	22	5	the	the	DET
fnp-2920	22	6	emerging	emerge	VERB
fnp-2920	22	7	concept	concept	NOUN
fnp-2920	22	8	of	of	ADP
fnp-2920	22	9	enteric	enteric	ADJ
fnp-2920	22	10	synucleinopathy	synucleinopathy	NOUN
fnp-2920	22	11	.	.	PUNCT
fnp-2920	23	1	although	although	SCONJ
fnp-2920	23	2	these	these	DET
fnp-2920	23	3	observations	observation	NOUN
fnp-2920	23	4	open	open	VERB
fnp-2920	23	5	up	up	ADP
fnp-2920	23	6	interesting	interesting	ADJ
fnp-2920	23	7	perspectives	perspective	NOUN
fnp-2920	23	8	on	on	ADP
fnp-2920	23	9	the	the	DET
fnp-2920	23	10	pathogenesis	pathogenesis	NOUN
fnp-2920	23	11	of	of	ADP
fnp-2920	23	12	neurodegenerative	neurodegenerative	ADJ
fnp-2920	23	13	disorders	disorder	NOUN
fnp-2920	23	14	,	,	PUNCT
fnp-2920	23	15	some	some	DET
fnp-2920	23	16	important	important	ADJ
fnp-2920	23	17	questions	question	NOUN
fnp-2920	23	18	are	be	AUX
fnp-2920	23	19	still	still	ADV
fnp-2920	23	20	pending	pende	VERB
fnp-2920	23	21	,	,	PUNCT
fnp-2920	23	22	among	among	ADP
fnp-2920	23	23	which	which	PRON
fnp-2920	23	24	are	be	AUX
fnp-2920	23	25	:	:	PUNCT
fnp-2920	23	26	what	what	PRON
fnp-2920	23	27	are	be	AUX
fnp-2920	23	28	the	the	DET
fnp-2920	23	29	biochemical	biochemical	ADJ
fnp-2920	23	30	and	and	CCONJ
fnp-2920	23	31	pathological	pathological	ADJ
fnp-2920	23	32	characteristics	characteristic	NOUN
fnp-2920	23	33	of	of	ADP
fnp-2920	23	34	alpha	alpha	NOUN
fnp-2920	23	35	-	-	PUNCT
fnp-2920	23	36	synuclein	synuclein	NOUN
fnp-2920	23	37	deposits	deposit	NOUN
fnp-2920	23	38	in	in	ADP
fnp-2920	23	39	the	the	DET
fnp-2920	23	40	ens	en	NOUN
fnp-2920	23	41	?	?	PROPN
fnp-2920	24	1	are	be	AUX
fnp-2920	24	2	they	they	PRON
fnp-2920	24	3	similar	similar	ADJ
fnp-2920	24	4	to	to	ADP
fnp-2920	24	5	those	those	PRON
fnp-2920	24	6	observed	observe	VERB
fnp-2920	24	7	in	in	ADP
fnp-2920	24	8	the	the	DET
fnp-2920	24	9	cns	cns	NOUN
fnp-2920	24	10	?	?	PUNCT
fnp-2920	25	1	is	be	AUX
fnp-2920	25	2	there	there	PRON
fnp-2920	25	3	any	any	DET
fnp-2920	25	4	neuronal	neuronal	ADJ
fnp-2920	25	5	loss	loss	NOUN
fnp-2920	25	6	in	in	ADP
fnp-2920	25	7	the	the	DET
fnp-2920	25	8	ens	ens	NOUN
fnp-2920	25	9	in	in	ADP
fnp-2920	25	10	pd	pd	PROPN
fnp-2920	25	11	?	?	PROPN
fnp-2920	26	1	besides	besides	SCONJ
fnp-2920	26	2	pd	pd	PROPN
fnp-2920	26	3	,	,	PUNCT
fnp-2920	26	4	are	be	AUX
fnp-2920	26	5	gut	gut	NOUN
fnp-2920	26	6	-	-	PUNCT
fnp-2920	26	7	brain	brain	NOUN
fnp-2920	26	8	interactions	interaction	NOUN
fnp-2920	26	9	important	important	ADJ
fnp-2920	26	10	in	in	ADP
fnp-2920	26	11	other	other	ADJ
fnp-2920	26	12	neurodegenerative	neurodegenerative	ADJ
fnp-2920	26	13	disorders	disorder	NOUN
fnp-2920	26	14	?	?	PUNCT
fnp-2920	27	1	here	here	ADV
fnp-2920	27	2	,	,	PUNCT
fnp-2920	27	3	we	we	PRON
fnp-2920	27	4	first	first	ADV
fnp-2920	27	5	provide	provide	VERB
fnp-2920	27	6	a	a	DET
fnp-2920	27	7	brief	brief	ADJ
fnp-2920	27	8	overview	overview	NOUN
fnp-2920	27	9	of	of	ADP
fnp-2920	27	10	the	the	DET
fnp-2920	27	11	normal	normal	ADJ
fnp-2920	27	12	expression	expression	NOUN
fnp-2920	27	13	profiles	profile	NOUN
fnp-2920	27	14	of	of	ADP
fnp-2920	27	15	alpha	alpha	NOUN
fnp-2920	27	16	-	-	PUNCT
fnp-2920	27	17	synuclein	synuclein	NOUN
fnp-2920	27	18	in	in	ADP
fnp-2920	27	19	the	the	DET
fnp-2920	27	20	ens	en	NOUN
fnp-2920	27	21	,	,	PUNCT
fnp-2920	27	22	before	before	ADP
fnp-2920	27	23	discussing	discuss	VERB
fnp-2920	27	24	these	these	DET
fnp-2920	27	25	questions	question	NOUN
fnp-2920	27	26	and	and	CCONJ
fnp-2920	27	27	the	the	DET
fnp-2920	27	28	arguments	argument	NOUN
fnp-2920	27	29	for	for	ADP
fnp-2920	27	30	and	and	CCONJ
fnp-2920	27	31	against	against	ADP
fnp-2920	27	32	the	the	DET
fnp-2920	27	33	existence	existence	NOUN
fnp-2920	27	34	of	of	ADP
fnp-2920	27	35	enteric	enteric	ADJ
fnp-2920	27	36	synucleinopathies	synucleinopathie	NOUN
fnp-2920	27	37	.	.	PUNCT
fnp-2920	28	1	figure	figure	NOUN
fnp-2920	28	2	1	1	NUM
fnp-2920	28	3	.	.	PUNCT
fnp-2920	28	4	anatomical	anatomical	ADJ
fnp-2920	28	5	organisation	organisation	NOUN
fnp-2920	28	6	and	and	CCONJ
fnp-2920	28	7	local	local	ADJ
fnp-2920	28	8	reflexes	reflex	NOUN
fnp-2920	28	9	of	of	ADP
fnp-2920	28	10	the	the	DET
fnp-2920	28	11	enteric	enteric	ADJ
fnp-2920	28	12	nervous	nervous	ADJ
fnp-2920	28	13	system	system	NOUN
fnp-2920	28	14	.	.	PUNCT
fnp-2920	29	1	the	the	DET
fnp-2920	29	2	ens	ens	PROPN
fnp-2920	29	3	is	be	AUX
fnp-2920	29	4	a	a	DET
fnp-2920	29	5	neuronal	neuronal	ADJ
fnp-2920	29	6	network	network	NOUN
fnp-2920	29	7	embedded	embed	VERB
fnp-2920	29	8	within	within	ADP
fnp-2920	29	9	the	the	DET
fnp-2920	29	10	gi	gi	NOUN
fnp-2920	29	11	tract	tract	NOUN
fnp-2920	29	12	and	and	CCONJ
fnp-2920	29	13	distributed	distribute	VERB
fnp-2920	29	14	from	from	ADP
fnp-2920	29	15	the	the	DET
fnp-2920	29	16	lower	low	ADJ
fnp-2920	29	17	oesophagus	oesophagus	NOUN
fnp-2920	29	18	to	to	ADP
fnp-2920	29	19	the	the	DET
fnp-2920	29	20	rectum	rectum	NOUN
fnp-2920	29	21	.	.	PUNCT
fnp-2920	30	1	it	it	PRON
fnp-2920	30	2	is	be	AUX
fnp-2920	30	3	organized	organize	VERB
fnp-2920	30	4	in	in	ADP
fnp-2920	30	5	two	two	NUM
fnp-2920	30	6	major	major	ADJ
fnp-2920	30	7	ganglionated	ganglionate	VERB
fnp-2920	30	8	plexuses	plexus	NOUN
fnp-2920	30	9	,	,	PUNCT
fnp-2920	30	10	the	the	DET
fnp-2920	30	11	myenteric	myenteric	ADJ
fnp-2920	30	12	(	(	PUNCT
fnp-2920	30	13	mp	mp	PROPN
fnp-2920	30	14	or	or	CCONJ
fnp-2920	30	15	auerbach	auerbach	VERB
fnp-2920	30	16	’s	’s	PART
fnp-2920	30	17	plexus	plexus	NOUN
fnp-2920	30	18	)	)	PUNCT
fnp-2920	30	19	mainly	mainly	ADV
fnp-2920	30	20	involved	involve	VERB
fnp-2920	30	21	in	in	ADP
fnp-2920	30	22	the	the	DET
fnp-2920	30	23	control	control	NOUN
fnp-2920	30	24	of	of	ADP
fnp-2920	30	25	smooth	smooth	ADJ
fnp-2920	30	26	muscle	muscle	NOUN
fnp-2920	30	27	activity	activity	NOUN
fnp-2920	30	28	,	,	PUNCT
fnp-2920	30	29	and	and	CCONJ
fnp-2920	30	30	the	the	DET
fnp-2920	30	31	submucosal	submucosal	NOUN
fnp-2920	30	32	(	(	PUNCT
fnp-2920	30	33	smp	smp	PROPN
fnp-2920	30	34	or	or	CCONJ
fnp-2920	30	35	meissner	meissner	PROPN
fnp-2920	30	36	’s	’s	PART
fnp-2920	30	37	plexus	plexus	NOUN
fnp-2920	30	38	)	)	PUNCT
fnp-2920	30	39	,	,	PUNCT
fnp-2920	30	40	which	which	PRON
fnp-2920	30	41	regulates	regulate	VERB
fnp-2920	30	42	secretion	secretion	NOUN
fnp-2920	30	43	(	(	PUNCT
fnp-2920	30	44	sn	sn	NOUN
fnp-2920	30	45	,	,	PUNCT
fnp-2920	30	46	secretory	secretory	ADJ
fnp-2920	30	47	neurons	neuron	NOUN
fnp-2920	30	48	)	)	PUNCT
fnp-2920	30	49	and	and	CCONJ
fnp-2920	30	50	microvasculature	microvasculature	NOUN
fnp-2920	30	51	.	.	PUNCT
fnp-2920	31	1	compared	compare	VERB
fnp-2920	31	2	to	to	ADP
fnp-2920	31	3	other	other	ADJ
fnp-2920	31	4	sections	section	NOUN
fnp-2920	31	5	of	of	ADP
fnp-2920	31	6	the	the	DET
fnp-2920	31	7	peripheral	peripheral	ADJ
fnp-2920	31	8	nervous	nervous	ADJ
fnp-2920	31	9	system	system	NOUN
fnp-2920	31	10	,	,	PUNCT
fnp-2920	31	11	the	the	DET
fnp-2920	31	12	ens	ens	NOUN
fnp-2920	31	13	shows	show	VERB
fnp-2920	31	14	unique	unique	ADJ
fnp-2920	31	15	features	feature	NOUN
fnp-2920	31	16	that	that	PRON
fnp-2920	31	17	closely	closely	ADV
fnp-2920	31	18	resemble	resemble	VERB
fnp-2920	31	19	some	some	PRON
fnp-2920	31	20	of	of	ADP
fnp-2920	31	21	the	the	DET
fnp-2920	31	22	cns	cns	NOUN
fnp-2920	31	23	:	:	PUNCT
fnp-2920	31	24	it	it	PRON
fnp-2920	31	25	contains	contain	VERB
fnp-2920	31	26	a	a	DET
fnp-2920	31	27	variety	variety	NOUN
fnp-2920	31	28	of	of	ADP
fnp-2920	31	29	functionally	functionally	ADV
fnp-2920	31	30	distinct	distinct	ADJ
fnp-2920	31	31	enteric	enteric	ADJ
fnp-2920	31	32	neurons	neuron	NOUN
fnp-2920	31	33	along	along	ADP
fnp-2920	31	34	with	with	ADP
fnp-2920	31	35	a	a	DET
fnp-2920	31	36	vast	vast	ADJ
fnp-2920	31	37	repertoire	repertoire	NOUN
fnp-2920	31	38	of	of	ADP
fnp-2920	31	39	neurotransmitters	neurotransmitter	NOUN
fnp-2920	31	40	and	and	CCONJ
fnp-2920	31	41	intercellular	intercellular	ADJ
fnp-2920	31	42	messengers	messenger	NOUN
fnp-2920	31	43	which	which	PRON
fnp-2920	31	44	are	be	AUX
fnp-2920	31	45	the	the	DET
fnp-2920	31	46	basis	basis	NOUN
fnp-2920	31	47	for	for	ADP
fnp-2920	31	48	enteric	enteric	ADJ
fnp-2920	31	49	neurotransmission	neurotransmission	NOUN
fnp-2920	31	50	.	.	PUNCT
fnp-2920	32	1	it	it	PRON
fnp-2920	32	2	also	also	ADV
fnp-2920	32	3	harbours	harbour	VERB
fnp-2920	32	4	a	a	DET
fnp-2920	32	5	prominent	prominent	ADJ
fnp-2920	32	6	component	component	NOUN
fnp-2920	32	7	of	of	ADP
fnp-2920	32	8	glial	glial	ADJ
fnp-2920	32	9	cells	cell	NOUN
fnp-2920	32	10	(	(	PUNCT
fnp-2920	32	11	egc	egc	ADJ
fnp-2920	32	12	for	for	ADP
fnp-2920	32	13	enteric	enteric	ADJ
fnp-2920	32	14	glial	glial	ADJ
fnp-2920	32	15	cells	cell	NOUN
fnp-2920	32	16	)	)	PUNCT
fnp-2920	32	17	which	which	PRON
fnp-2920	32	18	,	,	PUNCT
fnp-2920	32	19	like	like	ADP
fnp-2920	32	20	astrocytes	astrocyte	NOUN
fnp-2920	32	21	in	in	ADP
fnp-2920	32	22	the	the	DET
fnp-2920	32	23	cns	cns	NOUN
fnp-2920	32	24	,	,	PUNCT
fnp-2920	32	25	contribute	contribute	VERB
fnp-2920	32	26	to	to	ADP
fnp-2920	32	27	support	support	NOUN
fnp-2920	32	28	,	,	PUNCT
fnp-2920	32	29	protection	protection	NOUN
fnp-2920	32	30	and	and	CCONJ
fnp-2920	32	31	maintenance	maintenance	NOUN
fnp-2920	32	32	of	of	ADP
fnp-2920	32	33	the	the	DET
fnp-2920	32	34	neural	neural	ADJ
fnp-2920	32	35	networks	network	NOUN
fnp-2920	32	36	.	.	PUNCT
fnp-2920	33	1	local	local	ADJ
fnp-2920	33	2	distention	distention	NOUN
fnp-2920	33	3	of	of	ADP
fnp-2920	33	4	the	the	DET
fnp-2920	33	5	intestinal	intestinal	ADJ
fnp-2920	33	6	wall	wall	NOUN
fnp-2920	33	7	and	and	CCONJ
fnp-2920	33	8	chemical	chemical	ADJ
fnp-2920	33	9	contents	content	NOUN
fnp-2920	33	10	in	in	ADP
fnp-2920	33	11	the	the	DET
fnp-2920	33	12	gut	gut	NOUN
fnp-2920	33	13	lumen	luman	NOUN
fnp-2920	33	14	activate	activate	VERB
fnp-2920	33	15	intrinsic	intrinsic	ADJ
fnp-2920	33	16	primary	primary	ADJ
fnp-2920	33	17	afferent	afferent	NOUN
fnp-2920	33	18	neurons	neuron	NOUN
fnp-2920	33	19	(	(	PUNCT
fnp-2920	33	20	ipan	ipan	NOUN
fnp-2920	33	21	)	)	PUNCT
fnp-2920	33	22	located	locate	VERB
fnp-2920	33	23	in	in	ADP
fnp-2920	33	24	both	both	CCONJ
fnp-2920	33	25	the	the	DET
fnp-2920	33	26	smp	smp	NOUN
fnp-2920	33	27	and	and	CCONJ
fnp-2920	33	28	mp	mp	PROPN
fnp-2920	33	29	.	.	PUNCT
fnp-2920	34	1	the	the	DET
fnp-2920	34	2	ipan	ipan	NOUN
fnp-2920	34	3	projects	project	VERB
fnp-2920	34	4	both	both	CCONJ
fnp-2920	34	5	in	in	ADP
fnp-2920	34	6	oral	oral	ADJ
fnp-2920	34	7	and	and	CCONJ
fnp-2920	34	8	anal	anal	ADJ
fnp-2920	34	9	directions	direction	NOUN
fnp-2920	34	10	to	to	PART
fnp-2920	34	11	synapse	synapse	VERB
fnp-2920	34	12	with	with	ADP
fnp-2920	34	13	interneurons	interneuron	NOUN
fnp-2920	34	14	(	(	PUNCT
fnp-2920	34	15	in	in	ADP
fnp-2920	34	16	)	)	PUNCT
fnp-2920	34	17	and	and	CCONJ
fnp-2920	34	18	motor	motor	NOUN
fnp-2920	34	19	neurons	neuron	NOUN
fnp-2920	34	20	(	(	PUNCT
fnp-2920	34	21	mn	mn	PROPN
fnp-2920	34	22	)	)	PUNCT
fnp-2920	34	23	.	.	PUNCT
fnp-2920	35	1	cholinergic	cholinergic	NOUN
fnp-2920	35	2	(	(	PUNCT
fnp-2920	35	3	ach	ach	PROPN
fnp-2920	35	4	)	)	PUNCT
fnp-2920	35	5	mn	mn	PROPN
fnp-2920	35	6	in	in	ADP
fnp-2920	35	7	red	red	PROPN
fnp-2920	35	8	are	be	AUX
fnp-2920	35	9	excitatory	excitatory	ADJ
fnp-2920	35	10	while	while	SCONJ
fnp-2920	35	11	nitrergic	nitrergic	ADJ
fnp-2920	35	12	(	(	PUNCT
fnp-2920	35	13	no	no	INTJ
fnp-2920	35	14	)	)	PUNCT
fnp-2920	35	15	mn	mn	PROPN
fnp-2920	35	16	in	in	ADP
fnp-2920	35	17	green	green	PROPN
fnp-2920	35	18	are	be	AUX
fnp-2920	35	19	inhibitory	inhibitory	ADJ
fnp-2920	35	20	.	.	PUNCT
fnp-2920	36	1	the	the	DET
fnp-2920	36	2	peristaltic	peristaltic	ADJ
fnp-2920	36	3	reflex	reflex	NOUN
fnp-2920	36	4	includes	include	VERB
fnp-2920	36	5	an	an	DET
fnp-2920	36	6	ascending	ascend	VERB
fnp-2920	36	7	excitatory	excitatory	NOUN
fnp-2920	36	8	reflex	reflex	NOUN
fnp-2920	36	9	mediated	mediate	VERB
fnp-2920	36	10	by	by	ADP
fnp-2920	36	11	cholinergic	cholinergic	PROPN
fnp-2920	36	12	mn	mn	PROPN
fnp-2920	36	13	and	and	CCONJ
fnp-2920	36	14	elicits	elicit	VERB
fnp-2920	36	15	contraction	contraction	NOUN
fnp-2920	36	16	of	of	ADP
fnp-2920	36	17	the	the	DET
fnp-2920	36	18	circular	circular	ADJ
fnp-2920	36	19	or	or	CCONJ
fnp-2920	36	20	longitudinal	longitudinal	ADJ
fnp-2920	36	21	smooth	smooth	ADJ
fnp-2920	36	22	muscles	muscle	NOUN
fnp-2920	36	23	located	locate	VERB
fnp-2920	36	24	orally	orally	ADV
fnp-2920	36	25	to	to	ADP
fnp-2920	36	26	the	the	DET
fnp-2920	36	27	site	site	NOUN
fnp-2920	36	28	of	of	ADP
fnp-2920	36	29	stimulation	stimulation	NOUN
fnp-2920	36	30	.	.	PUNCT
fnp-2920	37	1	the	the	DET
fnp-2920	37	2	descending	descend	VERB
fnp-2920	37	3	inhibitory	inhibitory	ADJ
fnp-2920	37	4	reflex	reflex	NOUN
fnp-2920	37	5	involves	involve	VERB
fnp-2920	37	6	inhibitory	inhibitory	ADJ
fnp-2920	37	7	nitrergic	nitrergic	ADJ
fnp-2920	37	8	mn	mn	PROPN
fnp-2920	37	9	that	that	PRON
fnp-2920	37	10	elicit	elicit	VERB
fnp-2920	37	11	relaxation	relaxation	NOUN
fnp-2920	37	12	of	of	ADP
fnp-2920	37	13	the	the	DET
fnp-2920	37	14	circular	circular	ADJ
fnp-2920	37	15	muscles	muscle	NOUN
fnp-2920	37	16	and	and	CCONJ
fnp-2920	37	17	longitudinal	longitudinal	ADJ
fnp-2920	37	18	muscles	muscle	NOUN
fnp-2920	37	19	located	locate	VERB
fnp-2920	37	20	anally	anally	ADV
fnp-2920	37	21	to	to	ADP
fnp-2920	37	22	the	the	DET
fnp-2920	37	23	site	site	NOUN
fnp-2920	37	24	of	of	ADP
fnp-2920	37	25	stimulation	stimulation	NOUN
fnp-2920	37	26	.	.	PUNCT
fnp-2920	38	1	alpha	alpha	NOUN
fnp-2920	38	2	-	-	PUNCT
fnp-2920	38	3	synuclein	synuclein	NOUN
fnp-2920	38	4	is	be	AUX
fnp-2920	38	5	physiologically	physiologically	ADV
fnp-2920	38	6	expressed	express	VERB
fnp-2920	38	7	by	by	ADP
fnp-2920	38	8	enteric	enteric	ADJ
fnp-2920	38	9	neurons	neuron	NOUN
fnp-2920	38	10	alpha	alpha	NOUN
fnp-2920	38	11	-	-	PUNCT
fnp-2920	38	12	synuclein	synuclein	NOUN
fnp-2920	38	13	was	be	AUX
fnp-2920	38	14	first	first	ADV
fnp-2920	38	15	isolated	isolate	VERB
fnp-2920	38	16	in	in	ADP
fnp-2920	38	17	1988	1988	NUM
fnp-2920	38	18	from	from	ADP
fnp-2920	38	19	the	the	DET
fnp-2920	38	20	electric	electric	ADJ
fnp-2920	38	21	organ	organ	NOUN
fnp-2920	38	22	of	of	ADP
fnp-2920	38	23	the	the	DET
fnp-2920	38	24	pacific	pacific	PROPN
fnp-2920	38	25	electric	electric	PROPN
fnp-2920	38	26	ray	ray	PROPN
fnp-2920	38	27	torpedo	torpedo	NOUN
fnp-2920	38	28	californica	californica	NOUN
fnp-2920	38	29	.	.	PUNCT
fnp-2920	39	1	in	in	ADP
fnp-2920	39	2	addition	addition	NOUN
fnp-2920	39	3	to	to	ADP
fnp-2920	39	4	its	its	PRON
fnp-2920	39	5	strong	strong	ADJ
fnp-2920	39	6	presynaptic	presynaptic	ADJ
fnp-2920	39	7	localisation	localisation	NOUN
fnp-2920	39	8	,	,	PUNCT
fnp-2920	39	9	maroteaux	maroteaux	INTJ
fnp-2920	39	10	et	et	PROPN
fnp-2920	39	11	al	al	PROPN
fnp-2920	39	12	.	.	PROPN
fnp-2920	39	13	,	,	PUNCT
fnp-2920	39	14	also	also	ADV
fnp-2920	39	15	identified	identify	VERB
fnp-2920	39	16	alpha	alpha	NOUN
fnp-2920	39	17	-	-	PUNCT
fnp-2920	39	18	synuclein	synuclein	NOUN
fnp-2920	39	19	in	in	ADP
fnp-2920	39	20	the	the	DET
fnp-2920	39	21	nucleus	nucleus	NOUN
fnp-2920	39	22	,	,	PUNCT
fnp-2920	39	23	thus	thus	ADV
fnp-2920	39	24	accounting	account	VERB
fnp-2920	39	25	for	for	ADP
fnp-2920	39	26	the	the	DET
fnp-2920	39	27	name	name	NOUN
fnp-2920	39	28	‘	'	PUNCT
fnp-2920	39	29	synuclein	synuclein	NOUN
fnp-2920	39	30	’	'	PUNCT
fnp-2920	39	31	(	(	PUNCT
fnp-2920	39	32	synapse	synapse	VERB
fnp-2920	39	33	+	+	CCONJ
fnp-2920	39	34	nucleus	nucleus	NOUN
fnp-2920	39	35	)	)	PUNCT
fnp-2920	40	1	[	[	X
fnp-2920	40	2	12	12	NUM
fnp-2920	40	3	]	]	PUNCT
fnp-2920	40	4	.	.	PUNCT
fnp-2920	41	1	several	several	ADJ
fnp-2920	41	2	studies	study	NOUN
fnp-2920	41	3	have	have	AUX
fnp-2920	41	4	documented	document	VERB
fnp-2920	41	5	the	the	DET
fnp-2920	41	6	physiological	physiological	ADJ
fnp-2920	41	7	function	function	NOUN
fnp-2920	41	8	of	of	ADP
fnp-2920	41	9	alpha	alpha	NOUN
fnp-2920	41	10	-	-	PUNCT
fnp-2920	41	11	synuclein	synuclein	NOUN
fnp-2920	41	12	in	in	ADP
fnp-2920	41	13	modulating	modulate	VERB
fnp-2920	41	14	synaptic	synaptic	ADJ
fnp-2920	41	15	vesicle	vesicle	NOUN
fnp-2920	41	16	release	release	NOUN
fnp-2920	41	17	[	[	X
fnp-2920	41	18	13	13	NUM
fnp-2920	41	19	]	]	PUNCT
fnp-2920	41	20	.	.	PUNCT
fnp-2920	42	1	human	human	ADJ
fnp-2920	42	2	alpha	alpha	PROPN
fnp-2920	42	3	-	-	PUNCT
fnp-2920	42	4	synuclein	synuclein	NOUN
fnp-2920	42	5	,	,	PUNCT
fnp-2920	42	6	140	140	NUM
fnp-2920	42	7	amino	amino	NOUN
fnp-2920	42	8	acids	acid	NOUN
fnp-2920	42	9	in	in	ADP
fnp-2920	42	10	length	length	NOUN
fnp-2920	42	11	,	,	PUNCT
fnp-2920	42	12	is	be	AUX
fnp-2920	42	13	mainly	mainly	ADV
fnp-2920	42	14	expressed	express	VERB
fnp-2920	42	15	by	by	ADP
fnp-2920	42	16	cns	cns	NOUN
fnp-2920	42	17	neurons	neuron	NOUN
fnp-2920	42	18	and	and	CCONJ
fnp-2920	42	19	erythrocytes	erythrocyte	NOUN
fnp-2920	42	20	and	and	CCONJ
fnp-2920	42	21	is	be	AUX
fnp-2920	42	22	composed	compose	VERB
fnp-2920	42	23	of	of	ADP
fnp-2920	42	24	3	3	NUM
fnp-2920	42	25	different	different	ADJ
fnp-2920	42	26	functional	functional	ADJ
fnp-2920	42	27	regions	region	NOUN
fnp-2920	42	28	(	(	PUNCT
fnp-2920	42	29	figure	figure	NOUN
fnp-2920	42	30	2a	2a	NUM
fnp-2920	42	31	)	)	PUNCT
fnp-2920	43	1	[	[	X
fnp-2920	43	2	13	13	NUM
fnp-2920	43	3	]	]	PUNCT
fnp-2920	43	4	.	.	PUNCT
fnp-2920	44	1	there	there	PRON
fnp-2920	44	2	is	be	VERB
fnp-2920	44	3	still	still	ADV
fnp-2920	44	4	open	open	ADJ
fnp-2920	44	5	debate	debate	NOUN
fnp-2920	44	6	about	about	ADP
fnp-2920	44	7	the	the	DET
fnp-2920	44	8	physiological	physiological	ADJ
fnp-2920	44	9	structure	structure	NOUN
fnp-2920	44	10	of	of	ADP
fnp-2920	44	11	brain	brain	NOUN
fnp-2920	44	12	alpha	alpha	NOUN
fnp-2920	44	13	–	–	PUNCT
fnp-2920	44	14	synuclein	synuclein	NOUN
fnp-2920	44	15	as	as	SCONJ
fnp-2920	44	16	some	some	DET
fnp-2920	44	17	research	research	NOUN
fnp-2920	44	18	groups	group	NOUN
fnp-2920	44	19	concluded	conclude	VERB
fnp-2920	44	20	that	that	SCONJ
fnp-2920	44	21	it	it	PRON
fnp-2920	44	22	occurs	occur	VERB
fnp-2920	44	23	as	as	ADP
fnp-2920	44	24	a	a	DET
fnp-2920	44	25	helically	helically	ADV
fnp-2920	44	26	folded	fold	VERB
fnp-2920	44	27	tetramer	tetramer	PROPN
fnp-2920	45	1	[	[	X
fnp-2920	45	2	14	14	NUM
fnp-2920	45	3	]	]	PUNCT
fnp-2920	45	4	,	,	PUNCT
fnp-2920	45	5	while	while	SCONJ
fnp-2920	45	6	others	other	NOUN
fnp-2920	45	7	counterclaim	counterclaim	VERB
fnp-2920	45	8	that	that	SCONJ
fnp-2920	45	9	it	it	PRON
fnp-2920	45	10	exists	exist	VERB
fnp-2920	45	11	primarily	primarily	ADV
fnp-2920	45	12	as	as	ADP
fnp-2920	45	13	a	a	DET
fnp-2920	45	14	disordered	disordered	ADJ
fnp-2920	45	15	monomer	monomer	NOUN
fnp-2920	45	16	[	[	X
fnp-2920	45	17	15	15	NUM
fnp-2920	45	18	]	]	PUNCT
fnp-2920	45	19	.	.	PUNCT
fnp-2920	46	1	alpha	alpha	PROPN
fnp-2920	46	2	-	-	PUNCT
fnp-2920	46	3	synuclein	synuclein	PROPN
fnp-2920	46	4	has	have	VERB
fnp-2920	46	5	a	a	DET
fnp-2920	46	6	natural	natural	ADJ
fnp-2920	46	7	propensity	propensity	NOUN
fnp-2920	46	8	to	to	PART
fnp-2920	46	9	aggregate	aggregate	VERB
fnp-2920	46	10	as	as	ADP
fnp-2920	46	11	amyloid	amyloid	NOUN
fnp-2920	46	12	structures	structure	NOUN
fnp-2920	46	13	in	in	ADP
fnp-2920	46	14	a	a	DET
fnp-2920	46	15	nucleation	nucleation	NOUN
fnp-2920	46	16	-	-	PUNCT
fnp-2920	46	17	dependent	dependent	ADJ
fnp-2920	46	18	process	process	NOUN
fnp-2920	46	19	in	in	ADP
fnp-2920	46	20	which	which	PRON
fnp-2920	46	21	monomers	monomer	NOUN
fnp-2920	46	22	assemble	assemble	VERB
fnp-2920	46	23	via	via	ADP
fnp-2920	46	24	oligomers	oligomer	NOUN
fnp-2920	46	25	into	into	ADP
fnp-2920	46	26	fibrils	fibril	NOUN
fnp-2920	46	27	[	[	X
fnp-2920	46	28	16	16	NUM
fnp-2920	46	29	]	]	PUNCT
fnp-2920	46	30	(	(	PUNCT
fnp-2920	46	31	figure	figure	NOUN
fnp-2920	46	32	2b	2b	NOUN
fnp-2920	46	33	)	)	PUNCT
fnp-2920	46	34	.	.	PUNCT
fnp-2920	47	1	figure	figure	NOUN
fnp-2920	47	2	2	2	NUM
fnp-2920	47	3	.	.	PUNCT
fnp-2920	47	4	alpha	alpha	NOUN
fnp-2920	47	5	-	-	PUNCT
fnp-2920	47	6	synuclein	synuclein	NOUN
fnp-2920	47	7	structure	structure	NOUN
fnp-2920	47	8	and	and	CCONJ
fnp-2920	47	9	molecular	molecular	ADJ
fnp-2920	47	10	mechanism	mechanism	NOUN
fnp-2920	47	11	of	of	ADP
fnp-2920	47	12	its	its	PRON
fnp-2920	47	13	oligomerisation	oligomerisation	NOUN
fnp-2920	47	14	and	and	CCONJ
fnp-2920	47	15	fibrillogenesis	fibrillogenesis	NOUN
fnp-2920	47	16	.	.	PUNCT
fnp-2920	48	1	(	(	PUNCT
fnp-2920	48	2	a	a	X
fnp-2920	48	3	)	)	PUNCT
fnp-2920	48	4	schematic	schematic	ADJ
fnp-2920	48	5	representation	representation	NOUN
fnp-2920	48	6	of	of	ADP
fnp-2920	48	7	alpha	alpha	NOUN
fnp-2920	48	8	-	-	PUNCT
fnp-2920	48	9	synuclein	synuclein	NOUN
fnp-2920	48	10	,	,	PUNCT
fnp-2920	48	11	which	which	PRON
fnp-2920	48	12	is	be	AUX
fnp-2920	48	13	composed	compose	VERB
fnp-2920	48	14	of	of	ADP
fnp-2920	48	15	3	3	NUM
fnp-2920	48	16	distinct	distinct	ADJ
fnp-2920	48	17	regions	region	NOUN
fnp-2920	48	18	:	:	PUNCT
fnp-2920	48	19	(	(	PUNCT
fnp-2920	48	20	i	i	NOUN
fnp-2920	48	21	)	)	PUNCT
fnp-2920	48	22	an	an	DET
fnp-2920	48	23	n	n	CCONJ
fnp-2920	48	24	-	-	PUNCT
fnp-2920	48	25	terminal	terminal	ADJ
fnp-2920	48	26	domain	domain	NOUN
fnp-2920	48	27	(	(	PUNCT
fnp-2920	48	28	amino	amino	NOUN
fnp-2920	48	29	acids	acid	NOUN
fnp-2920	48	30	1–60	1–60	PROPN
fnp-2920	48	31	)	)	PUNCT
fnp-2920	48	32	that	that	PRON
fnp-2920	48	33	binds	bind	VERB
fnp-2920	48	34	lipids	lipid	NOUN
fnp-2920	48	35	and	and	CCONJ
fnp-2920	48	36	contains	contain	VERB
fnp-2920	48	37	the	the	DET
fnp-2920	48	38	lysines	lysine	NOUN
fnp-2920	48	39	that	that	PRON
fnp-2920	48	40	are	be	AUX
fnp-2920	48	41	ubiquitinated	ubiquitinated	ADJ
fnp-2920	48	42	(	(	PUNCT
fnp-2920	48	43	ii	ii	NOUN
fnp-2920	48	44	)	)	PUNCT
fnp-2920	48	45	a	a	DET
fnp-2920	48	46	central	central	ADJ
fnp-2920	48	47	domain	domain	NOUN
fnp-2920	48	48	known	know	VERB
fnp-2920	48	49	as	as	ADP
fnp-2920	48	50	the	the	DET
fnp-2920	48	51	non	non	ADJ
fnp-2920	48	52	-	-	ADJ
fnp-2920	48	53	amyloid	amyloid	ADJ
fnp-2920	48	54	component	component	NOUN
fnp-2920	48	55	(	(	PUNCT
fnp-2920	48	56	nac	nac	PROPN
fnp-2920	48	57	)	)	PUNCT
fnp-2920	48	58	(	(	PUNCT
fnp-2920	48	59	amino	amino	NOUN
fnp-2920	48	60	acids	acid	NOUN
fnp-2920	48	61	61–95	61–95	NUM
fnp-2920	48	62	)	)	PUNCT
fnp-2920	48	63	which	which	PRON
fnp-2920	48	64	is	be	AUX
fnp-2920	48	65	involved	involve	VERB
fnp-2920	48	66	in	in	ADP
fnp-2920	48	67	aggregation	aggregation	NOUN
fnp-2920	48	68	,	,	PUNCT
fnp-2920	48	69	and	and	CCONJ
fnp-2920	48	70	(	(	PUNCT
fnp-2920	48	71	iii	iii	NOUN
fnp-2920	48	72	)	)	PUNCT
fnp-2920	48	73	a	a	DET
fnp-2920	48	74	c	c	NOUN
fnp-2920	48	75	-	-	PUNCT
fnp-2920	48	76	terminal	terminal	ADJ
fnp-2920	48	77	acidic	acidic	ADJ
fnp-2920	48	78	tail	tail	NOUN
fnp-2920	48	79	(	(	PUNCT
fnp-2920	48	80	amino	amino	NOUN
fnp-2920	48	81	acids	acid	NOUN
fnp-2920	48	82	96–140	96–140	NUM
fnp-2920	48	83	)	)	PUNCT
fnp-2920	48	84	accountable	accountable	ADJ
fnp-2920	48	85	for	for	ADP
fnp-2920	48	86	most	most	ADJ
fnp-2920	48	87	interactions	interaction	NOUN
fnp-2920	48	88	with	with	ADP
fnp-2920	48	89	other	other	ADJ
fnp-2920	48	90	proteins	protein	NOUN
fnp-2920	48	91	and	and	CCONJ
fnp-2920	48	92	small	small	ADJ
fnp-2920	48	93	molecules	molecule	NOUN
fnp-2920	48	94	and	and	CCONJ
fnp-2920	48	95	that	that	PRON
fnp-2920	48	96	contains	contain	VERB
fnp-2920	48	97	most	most	ADJ
fnp-2920	48	98	of	of	ADP
fnp-2920	48	99	the	the	DET
fnp-2920	48	100	phosphorylation	phosphorylation	NOUN
fnp-2920	48	101	sites	site	NOUN
fnp-2920	48	102	including	include	VERB
fnp-2920	48	103	serine	serine	NOUN
fnp-2920	48	104	129	129	NUM
fnp-2920	48	105	.	.	PUNCT
fnp-2920	49	1	some	some	PRON
fnp-2920	49	2	of	of	ADP
fnp-2920	49	3	the	the	DET
fnp-2920	49	4	truncated	truncated	ADJ
fnp-2920	49	5	c	c	PROPN
fnp-2920	49	6	terminal	terminal	ADJ
fnp-2920	49	7	forms	form	NOUN
fnp-2920	49	8	of	of	ADP
fnp-2920	49	9	alpha	alpha	NOUN
fnp-2920	49	10	-	-	PUNCT
fnp-2920	49	11	synuclein	synuclein	NOUN
fnp-2920	49	12	are	be	AUX
fnp-2920	49	13	also	also	ADV
fnp-2920	49	14	shown	show	VERB
fnp-2920	49	15	.	.	PUNCT
fnp-2920	50	1	(	(	PUNCT
fnp-2920	50	2	b	b	X
fnp-2920	50	3	)	)	PUNCT
fnp-2920	50	4	illustration	illustration	NOUN
fnp-2920	50	5	of	of	ADP
fnp-2920	50	6	the	the	DET
fnp-2920	50	7	molecular	molecular	ADJ
fnp-2920	50	8	steps	step	NOUN
fnp-2920	50	9	involved	involve	VERB
fnp-2920	50	10	in	in	ADP
fnp-2920	50	11	alpha	alpha	NOUN
fnp-2920	50	12	-	-	PUNCT
fnp-2920	50	13	synuclein	synuclein	NOUN
fnp-2920	50	14	oligomerisation	oligomerisation	NOUN
fnp-2920	50	15	and	and	CCONJ
fnp-2920	50	16	fibrillogenesis	fibrillogenesis	NOUN
fnp-2920	50	17	leading	lead	VERB
fnp-2920	50	18	to	to	ADP
fnp-2920	50	19	lewy	lewy	PROPN
fnp-2920	50	20	body	body	NOUN
fnp-2920	50	21	formation	formation	NOUN
fnp-2920	50	22	.	.	PUNCT
fnp-2920	51	1	soluble	soluble	ADJ
fnp-2920	51	2	alpha	alpha	NOUN
fnp-2920	51	3	-	-	PUNCT
fnp-2920	51	4	synuclein	synuclein	NOUN
fnp-2920	51	5	is	be	AUX
fnp-2920	51	6	natively	natively	ADV
fnp-2920	51	7	unstructured	unstructured	ADJ
fnp-2920	51	8	and	and	CCONJ
fnp-2920	51	9	monomeric	monomeric	ADJ
fnp-2920	51	10	.	.	PUNCT
fnp-2920	52	1	under	under	ADP
fnp-2920	52	2	pathological	pathological	ADJ
fnp-2920	52	3	conditions	condition	NOUN
fnp-2920	52	4	,	,	PUNCT
fnp-2920	52	5	soluble	soluble	ADJ
fnp-2920	52	6	α	α	NOUN
fnp-2920	52	7	-	-	PUNCT
fnp-2920	52	8	synuclein	synuclein	NOUN
fnp-2920	52	9	forms	form	NOUN
fnp-2920	52	10	β	β	NOUN
fnp-2920	52	11	-	-	ADJ
fnp-2920	52	12	sheet	sheet	NOUN
fnp-2920	52	13	-	-	PUNCT
fnp-2920	52	14	like	like	ADJ
fnp-2920	52	15	oligomers	oligomer	NOUN
fnp-2920	52	16	(	(	PUNCT
fnp-2920	52	17	protofibrils	protofibril	NOUN
fnp-2920	52	18	)	)	PUNCT
fnp-2920	52	19	,	,	PUNCT
fnp-2920	52	20	which	which	PRON
fnp-2920	52	21	convert	convert	VERB
fnp-2920	52	22	into	into	ADP
fnp-2920	52	23	amyloid	amyloid	NOUN
fnp-2920	52	24	fibrils	fibril	NOUN
fnp-2920	52	25	and	and	CCONJ
fnp-2920	52	26	eventually	eventually	ADV
fnp-2920	52	27	deposit	deposit	VERB
fnp-2920	52	28	in	in	ADP
fnp-2920	52	29	lewy	lewy	PROPN
fnp-2920	52	30	bodies	body	NOUN
fnp-2920	52	31	.	.	PUNCT
fnp-2920	53	1	alpha	alpha	NOUN
fnp-2920	53	2	-	-	PUNCT
fnp-2920	53	3	synuclein	synuclein	NOUN
fnp-2920	53	4	is	be	AUX
fnp-2920	53	5	also	also	ADV
fnp-2920	53	6	expressed	express	VERB
fnp-2920	53	7	by	by	ADP
fnp-2920	53	8	enteric	enteric	ADJ
fnp-2920	53	9	neurons	neuron	NOUN
fnp-2920	53	10	.	.	PUNCT
fnp-2920	54	1	in	in	ADP
fnp-2920	54	2	rodents	rodent	NOUN
fnp-2920	54	3	,	,	PUNCT
fnp-2920	54	4	guinea	guinea	NOUN
fnp-2920	54	5	-	-	PUNCT
fnp-2920	54	6	pigs	pig	NOUN
fnp-2920	54	7	and	and	CCONJ
fnp-2920	54	8	human	human	ADJ
fnp-2920	54	9	alpha	alpha	NOUN
fnp-2920	54	10	-	-	PUNCT
fnp-2920	54	11	synuclein	synuclein	NOUN
fnp-2920	54	12	positive	positive	ADJ
fnp-2920	54	13	neurons	neuron	NOUN
fnp-2920	54	14	are	be	AUX
fnp-2920	54	15	present	present	ADJ
fnp-2920	54	16	in	in	ADP
fnp-2920	54	17	the	the	DET
fnp-2920	54	18	two	two	NUM
fnp-2920	54	19	plexuses	plexus	NOUN
fnp-2920	54	20	of	of	ADP
fnp-2920	54	21	the	the	DET
fnp-2920	54	22	ens	en	NOUN
fnp-2920	54	23	and	and	CCONJ
fnp-2920	54	24	along	along	ADP
fnp-2920	54	25	the	the	DET
fnp-2920	54	26	entire	entire	ADJ
fnp-2920	54	27	digestive	digestive	ADJ
fnp-2920	54	28	tract	tract	NOUN
fnp-2920	55	1	[	[	X
fnp-2920	55	2	5	5	NUM
fnp-2920	55	3	,	,	PUNCT
fnp-2920	55	4	17	17	NUM
fnp-2920	55	5	,	,	PUNCT
fnp-2920	55	6	18	18	NUM
fnp-2920	55	7	]	]	PUNCT
fnp-2920	55	8	(	(	PUNCT
fnp-2920	55	9	figure	figure	NOUN
fnp-2920	55	10	3	3	NUM
fnp-2920	55	11	)	)	PUNCT
fnp-2920	55	12	.	.	PUNCT
fnp-2920	56	1	using	use	VERB
fnp-2920	56	2	amine	amine	NOUN
fnp-2920	56	3	-	-	PUNCT
fnp-2920	56	4	reactive	reactive	ADJ
fnp-2920	56	5	cross	cross	NOUN
fnp-2920	56	6	-	-	ADJ
fnp-2920	56	7	linking	linking	ADJ
fnp-2920	56	8	,	,	PUNCT
fnp-2920	56	9	we	we	PRON
fnp-2920	56	10	showed	show	VERB
fnp-2920	56	11	that	that	SCONJ
fnp-2920	56	12	,	,	PUNCT
fnp-2920	56	13	unlike	unlike	ADP
fnp-2920	56	14	brain	brain	NOUN
fnp-2920	56	15	neurons	neuron	NOUN
fnp-2920	56	16	,	,	PUNCT
fnp-2920	56	17	alpha	alpha	NOUN
fnp-2920	56	18	-	-	PUNCT
fnp-2920	56	19	synuclein	synuclein	NOUN
fnp-2920	56	20	exists	exist	VERB
fnp-2920	56	21	primarily	primarily	ADV
fnp-2920	56	22	as	as	ADP
fnp-2920	56	23	a	a	DET
fnp-2920	56	24	monomer	monomer	NOUN
fnp-2920	56	25	in	in	ADP
fnp-2920	56	26	enteric	enteric	ADJ
fnp-2920	56	27	neurons	neuron	NOUN
fnp-2920	56	28	[	[	X
fnp-2920	56	29	19	19	NUM
fnp-2920	56	30	]	]	PUNCT
fnp-2920	56	31	.	.	PUNCT
fnp-2920	57	1	as	as	ADV
fnp-2920	57	2	far	far	ADV
fnp-2920	57	3	as	as	SCONJ
fnp-2920	57	4	we	we	PRON
fnp-2920	57	5	know	know	VERB
fnp-2920	57	6	,	,	PUNCT
fnp-2920	57	7	the	the	DET
fnp-2920	57	8	expression	expression	NOUN
fnp-2920	57	9	of	of	ADP
fnp-2920	57	10	alpha	alpha	NOUN
fnp-2920	57	11	-	-	PUNCT
fnp-2920	57	12	synuclein	synuclein	NOUN
fnp-2920	57	13	by	by	ADP
fnp-2920	57	14	enteric	enteric	ADJ
fnp-2920	57	15	glial	glial	ADJ
fnp-2920	57	16	cells	cell	NOUN
fnp-2920	57	17	,	,	PUNCT
fnp-2920	57	18	the	the	DET
fnp-2920	57	19	enteric	enteric	ADJ
fnp-2920	57	20	counterpart	counterpart	NOUN
fnp-2920	57	21	of	of	ADP
fnp-2920	57	22	cns	cns	PROPN
fnp-2920	57	23	astrocytes	astrocyte	NOUN
fnp-2920	57	24	,	,	PUNCT
fnp-2920	57	25	has	have	AUX
fnp-2920	57	26	not	not	PART
fnp-2920	57	27	been	be	AUX
fnp-2920	57	28	evaluated	evaluate	VERB
fnp-2920	57	29	.	.	PUNCT
fnp-2920	58	1	detailed	detailed	ADJ
fnp-2920	58	2	immunohistochemical	immunohistochemical	ADJ
fnp-2920	58	3	characterisation	characterisation	NOUN
fnp-2920	58	4	showed	show	VERB
fnp-2920	58	5	that	that	SCONJ
fnp-2920	58	6	alpha	alpha	NOUN
fnp-2920	58	7	-	-	PUNCT
fnp-2920	58	8	synuclein	synuclein	NOUN
fnp-2920	58	9	immunoreactive	immunoreactive	ADJ
fnp-2920	58	10	neurons	neuron	NOUN
fnp-2920	58	11	are	be	AUX
fnp-2920	58	12	mostly	mostly	ADV
fnp-2920	58	13	cholinergic	cholinergic	ADJ
fnp-2920	58	14	[	[	X
fnp-2920	58	15	17	17	NUM
fnp-2920	58	16	,	,	PUNCT
fnp-2920	58	17	18	18	NUM
fnp-2920	58	18	]	]	PUNCT
fnp-2920	58	19	(	(	PUNCT
fnp-2920	58	20	figure	figure	NOUN
fnp-2920	58	21	1	1	NUM
fnp-2920	58	22	)	)	PUNCT
fnp-2920	58	23	and	and	CCONJ
fnp-2920	58	24	that	that	SCONJ
fnp-2920	58	25	alpha	alpha	NOUN
fnp-2920	58	26	-	-	PUNCT
fnp-2920	58	27	synuclein	synuclein	NOUN
fnp-2920	58	28	is	be	AUX
fnp-2920	58	29	closely	closely	ADV
fnp-2920	58	30	associated	associate	VERB
fnp-2920	58	31	with	with	ADP
fnp-2920	58	32	the	the	DET
fnp-2920	58	33	vesicular	vesicular	ADJ
fnp-2920	58	34	apparatus	apparatus	NOUN
fnp-2920	58	35	[	[	X
fnp-2920	58	36	20	20	NUM
fnp-2920	58	37	]	]	PUNCT
fnp-2920	58	38	.	.	PUNCT
fnp-2920	59	1	although	although	SCONJ
fnp-2920	59	2	the	the	DET
fnp-2920	59	3	role	role	NOUN
fnp-2920	59	4	of	of	ADP
fnp-2920	59	5	alpha	alpha	NOUN
fnp-2920	59	6	-	-	PUNCT
fnp-2920	59	7	synuclein	synuclein	NOUN
fnp-2920	59	8	in	in	ADP
fnp-2920	59	9	the	the	DET
fnp-2920	59	10	ens	ens	NOUN
fnp-2920	59	11	is	be	AUX
fnp-2920	59	12	still	still	ADV
fnp-2920	59	13	mostly	mostly	ADV
fnp-2920	59	14	unknown	unknown	ADJ
fnp-2920	59	15	,	,	PUNCT
fnp-2920	59	16	a	a	DET
fnp-2920	59	17	recent	recent	ADJ
fnp-2920	59	18	study	study	NOUN
fnp-2920	59	19	suggested	suggest	VERB
fnp-2920	59	20	that	that	SCONJ
fnp-2920	59	21	it	it	PRON
fnp-2920	59	22	is	be	AUX
fnp-2920	59	23	involved	involve	VERB
fnp-2920	59	24	in	in	ADP
fnp-2920	59	25	the	the	DET
fnp-2920	59	26	development	development	NOUN
fnp-2920	59	27	and	and	CCONJ
fnp-2920	59	28	electrophysiological	electrophysiological	ADJ
fnp-2920	59	29	properties	property	NOUN
fnp-2920	59	30	of	of	ADP
fnp-2920	59	31	enteric	enteric	ADJ
fnp-2920	59	32	cholinergic	cholinergic	ADJ
fnp-2920	59	33	neurons	neuron	NOUN
fnp-2920	59	34	[	[	X
fnp-2920	59	35	21	21	NUM
fnp-2920	59	36	]	]	PUNCT
fnp-2920	59	37	.	.	PUNCT
fnp-2920	60	1	figure	figure	NOUN
fnp-2920	60	2	3	3	NUM
fnp-2920	60	3	.	.	PUNCT
fnp-2920	60	4	physiological	physiological	ADJ
fnp-2920	60	5	expression	expression	NOUN
fnp-2920	60	6	of	of	ADP
fnp-2920	60	7	alpha	alpha	NOUN
fnp-2920	60	8	-	-	PUNCT
fnp-2920	60	9	synuclein	synuclein	NOUN
fnp-2920	60	10	and	and	CCONJ
fnp-2920	60	11	phospho	phospho	ADJ
fnp-2920	60	12	-	-	PUNCT
fnp-2920	60	13	alpha	alpha	NOUN
fnp-2920	60	14	-	-	PUNCT
fnp-2920	60	15	synuclein	synuclein	NOUN
fnp-2920	60	16	histopathology	histopathology	NOUN
fnp-2920	60	17	in	in	ADP
fnp-2920	60	18	the	the	DET
fnp-2920	60	19	ens	ens	PROPN
fnp-2920	60	20	.	.	PROPN
fnp-2920	61	1	left	leave	VERB
fnp-2920	61	2	:	:	PUNCT
fnp-2920	61	3	anti	anti	ADJ
fnp-2920	61	4	-	-	ADJ
fnp-2920	61	5	alpha	alpha	ADJ
fnp-2920	61	6	-	-	PUNCT
fnp-2920	61	7	synuclein	synuclein	NOUN
fnp-2920	61	8	antibody	antibody	NOUN
fnp-2920	61	9	syn-1	syn-1	PUNCT
fnp-2920	61	10	was	be	AUX
fnp-2920	61	11	used	use	VERB
fnp-2920	61	12	to	to	PART
fnp-2920	61	13	detect	detect	VERB
fnp-2920	61	14	alpha	alpha	NOUN
fnp-2920	61	15	-	-	PUNCT
fnp-2920	61	16	synuclein	synuclein	NOUN
fnp-2920	61	17	in	in	ADP
fnp-2920	61	18	the	the	DET
fnp-2920	61	19	myenteric	myenteric	ADJ
fnp-2920	61	20	ganglia	ganglia	NOUN
fnp-2920	61	21	(	(	PUNCT
fnp-2920	61	22	colon	colon	NOUN
fnp-2920	61	23	)	)	PUNCT
fnp-2920	61	24	in	in	ADP
fnp-2920	61	25	a	a	DET
fnp-2920	61	26	control	control	NOUN
fnp-2920	61	27	subject	subject	NOUN
fnp-2920	61	28	devoid	devoid	ADJ
fnp-2920	61	29	of	of	ADP
fnp-2920	61	30	neurodegenerative	neurodegenerative	ADJ
fnp-2920	61	31	disorders	disorder	NOUN
fnp-2920	61	32	;	;	PUNCT
fnp-2920	61	33	βiii	βiii	PRON
fnp-2920	61	34	tubulin	tubulin	NOUN
fnp-2920	61	35	antibody	antibody	NOUN
fnp-2920	61	36	was	be	AUX
fnp-2920	61	37	used	use	VERB
fnp-2920	61	38	to	to	PART
fnp-2920	61	39	label	label	VERB
fnp-2920	61	40	the	the	DET
fnp-2920	61	41	neuronal	neuronal	ADJ
fnp-2920	61	42	network	network	NOUN
fnp-2920	61	43	.	.	PUNCT
fnp-2920	62	1	scale	scale	NOUN
fnp-2920	62	2	bar	bar	NOUN
fnp-2920	62	3	is	be	AUX
fnp-2920	62	4	50	50	NUM
fnp-2920	62	5	µm	µm	NOUN
fnp-2920	62	6	.	.	PUNCT
fnp-2920	63	1	right	right	ADJ
fnp-2920	63	2	:	:	PUNCT
fnp-2920	63	3	the	the	DET
fnp-2920	63	4	colon	colon	NOUN
fnp-2920	63	5	from	from	ADP
fnp-2920	63	6	a	a	DET
fnp-2920	63	7	pd	pd	NOUN
fnp-2920	63	8	patient	patient	NOUN
fnp-2920	63	9	was	be	AUX
fnp-2920	63	10	microdissected	microdissecte	VERB
fnp-2920	63	11	into	into	ADP
fnp-2920	63	12	mucosa	mucosa	NOUN
fnp-2920	63	13	,	,	PUNCT
fnp-2920	63	14	whole	whole	ADJ
fnp-2920	63	15	mount	mount	PROPN
fnp-2920	63	16	of	of	ADP
fnp-2920	63	17	submucosa	submucosa	PROPN
fnp-2920	63	18	and	and	CCONJ
fnp-2920	63	19	myenteric	myenteric	ADJ
fnp-2920	63	20	plexus	plexus	NOUN
fnp-2920	63	21	.	.	PUNCT
fnp-2920	64	1	each	each	DET
fnp-2920	64	2	part	part	NOUN
fnp-2920	64	3	was	be	AUX
fnp-2920	64	4	stained	stain	VERB
fnp-2920	64	5	with	with	ADP
fnp-2920	64	6	an	an	DET
fnp-2920	64	7	antibody	antibody	NOUN
fnp-2920	64	8	specific	specific	ADJ
fnp-2920	64	9	for	for	ADP
fnp-2920	64	10	the	the	DET
fnp-2920	64	11	phosphorylated	phosphorylate	VERB
fnp-2920	64	12	form	form	NOUN
fnp-2920	64	13	of	of	ADP
fnp-2920	64	14	alpha	alpha	NOUN
fnp-2920	64	15	-	-	PUNCT
fnp-2920	64	16	synuclein	synuclein	NOUN
fnp-2920	64	17	.	.	PUNCT
fnp-2920	65	1	phospho	phospho	ADJ
fnp-2920	65	2	-	-	PUNCT
fnp-2920	65	3	alpha	alpha	NOUN
fnp-2920	65	4	-	-	PUNCT
fnp-2920	65	5	synuclein	synuclein	NOUN
fnp-2920	65	6	histopathology	histopathology	NOUN
fnp-2920	65	7	with	with	ADP
fnp-2920	65	8	a	a	DET
fnp-2920	65	9	ln	ln	ADJ
fnp-2920	65	10	-	-	PUNCT
fnp-2920	65	11	like	like	ADJ
fnp-2920	65	12	pattern	pattern	NOUN
fnp-2920	65	13	is	be	AUX
fnp-2920	65	14	observed	observe	VERB
fnp-2920	65	15	in	in	ADP
fnp-2920	65	16	the	the	DET
fnp-2920	65	17	mucosa	mucosa	NOUN
fnp-2920	65	18	(	(	PUNCT
fnp-2920	65	19	arrow	arrow	NOUN
fnp-2920	65	20	,	,	PUNCT
fnp-2920	65	21	the	the	DET
fnp-2920	65	22	asterisk	asterisk	NOUN
fnp-2920	65	23	is	be	AUX
fnp-2920	65	24	for	for	ADP
fnp-2920	65	25	the	the	DET
fnp-2920	65	26	crypt	crypt	NOUN
fnp-2920	65	27	)	)	PUNCT
fnp-2920	65	28	and	and	CCONJ
fnp-2920	65	29	submucosa	submucosa	NOUN
fnp-2920	65	30	,	,	PUNCT
fnp-2920	65	31	while	while	SCONJ
fnp-2920	65	32	a	a	DET
fnp-2920	65	33	lb	lb	ADJ
fnp-2920	65	34	-	-	PUNCT
fnp-2920	65	35	like	like	ADJ
fnp-2920	65	36	structure	structure	NOUN
fnp-2920	65	37	is	be	AUX
fnp-2920	65	38	found	find	VERB
fnp-2920	65	39	in	in	ADP
fnp-2920	65	40	the	the	DET
fnp-2920	65	41	myenteric	myenteric	ADJ
fnp-2920	65	42	plexus	plexus	NOUN
fnp-2920	65	43	.	.	PUNCT
fnp-2920	66	1	scale	scale	NOUN
fnp-2920	66	2	bar	bar	NOUN
fnp-2920	66	3	is	be	AUX
fnp-2920	66	4	40	40	NUM
fnp-2920	66	5	µm	µm	NOUN
fnp-2920	66	6	.	.	PUNCT
fnp-2920	67	1	does	do	AUX
fnp-2920	67	2	the	the	DET
fnp-2920	67	3	ens	en	NOUN
fnp-2920	67	4	contain	contain	VERB
fnp-2920	67	5	pathological	pathological	ADJ
fnp-2920	67	6	aggregated	aggregate	VERB
fnp-2920	67	7	forms	form	NOUN
fnp-2920	67	8	of	of	ADP
fnp-2920	67	9	alpha	alpha	NOUN
fnp-2920	67	10	-	-	PUNCT
fnp-2920	67	11	synuclein	synuclein	NOUN
fnp-2920	67	12	?	?	PUNCT
fnp-2920	68	1	lewy	lewy	PROPN
fnp-2920	68	2	bodies	body	NOUN
fnp-2920	68	3	(	(	PUNCT
fnp-2920	68	4	lb	lb	NOUN
fnp-2920	68	5	)	)	PUNCT
fnp-2920	68	6	and	and	CCONJ
fnp-2920	68	7	lewy	lewy	PROPN
fnp-2920	68	8	neurites	neurites	PROPN
fnp-2920	68	9	(	(	PUNCT
fnp-2920	68	10	ln	ln	ADJ
fnp-2920	68	11	)	)	PUNCT
fnp-2920	68	12	are	be	AUX
fnp-2920	68	13	the	the	DET
fnp-2920	68	14	defining	define	VERB
fnp-2920	68	15	neuropathological	neuropathological	ADJ
fnp-2920	68	16	characteristics	characteristic	NOUN
fnp-2920	68	17	of	of	ADP
fnp-2920	68	18	pd	pd	PROPN
fnp-2920	68	19	.	.	PROPN
fnp-2920	68	20	lb	lb	PROPN
fnp-2920	68	21	typically	typically	ADV
fnp-2920	68	22	appear	appear	VERB
fnp-2920	68	23	in	in	ADP
fnp-2920	68	24	neuronal	neuronal	ADJ
fnp-2920	68	25	somata	somata	NOUN
fnp-2920	68	26	as	as	ADP
fnp-2920	68	27	eosinophilic	eosinophilic	ADJ
fnp-2920	68	28	,	,	PUNCT
fnp-2920	68	29	rounded	rounded	ADJ
fnp-2920	68	30	inclusions	inclusion	NOUN
fnp-2920	68	31	while	while	SCONJ
fnp-2920	68	32	ln	ln	ADV
fnp-2920	68	33	are	be	AUX
fnp-2920	68	34	strand	strand	NOUN
fnp-2920	68	35	-	-	PUNCT
fnp-2920	68	36	like	like	ADJ
fnp-2920	68	37	structures	structure	NOUN
fnp-2920	68	38	observed	observe	VERB
fnp-2920	68	39	in	in	ADP
fnp-2920	68	40	axons	axon	NOUN
fnp-2920	68	41	.	.	PUNCT
fnp-2920	69	1	in	in	ADP
fnp-2920	69	2	1997	1997	NUM
fnp-2920	69	3	,	,	PUNCT
fnp-2920	69	4	it	it	PRON
fnp-2920	69	5	was	be	AUX
fnp-2920	69	6	demonstrated	demonstrate	VERB
fnp-2920	69	7	that	that	SCONJ
fnp-2920	69	8	lb	lb	NUM
fnp-2920	69	9	and	and	CCONJ
fnp-2920	69	10	ln	ln	ADV
fnp-2920	69	11	isolated	isolate	VERB
fnp-2920	69	12	from	from	ADP
fnp-2920	69	13	pd	pd	PROPN
fnp-2920	69	14	brain	brain	NOUN
fnp-2920	69	15	were	be	AUX
fnp-2920	69	16	highly	highly	ADV
fnp-2920	69	17	immunoreactive	immunoreactive	ADJ
fnp-2920	69	18	for	for	ADP
fnp-2920	69	19	alpha	alpha	NOUN
fnp-2920	69	20	-	-	PUNCT
fnp-2920	69	21	synuclein	synuclein	NOUN
fnp-2920	69	22	,	,	PUNCT
fnp-2920	69	23	thereby	thereby	ADV
fnp-2920	69	24	suggesting	suggest	VERB
fnp-2920	69	25	that	that	SCONJ
fnp-2920	69	26	this	this	DET
fnp-2920	69	27	protein	protein	NOUN
fnp-2920	69	28	was	be	AUX
fnp-2920	69	29	one	one	NUM
fnp-2920	69	30	of	of	ADP
fnp-2920	69	31	the	the	DET
fnp-2920	69	32	main	main	ADJ
fnp-2920	69	33	components	component	NOUN
fnp-2920	69	34	of	of	ADP
fnp-2920	69	35	lewy	lewy	PROPN
fnp-2920	69	36	pathology	pathology	PROPN
fnp-2920	70	1	[	[	X
fnp-2920	70	2	22	22	NUM
fnp-2920	70	3	]	]	PUNCT
fnp-2920	70	4	.	.	PUNCT
fnp-2920	71	1	subsequent	subsequent	ADJ
fnp-2920	71	2	work	work	NOUN
fnp-2920	71	3	showed	show	VERB
fnp-2920	71	4	that	that	SCONJ
fnp-2920	71	5	alpha	alpha	NOUN
fnp-2920	71	6	-	-	PUNCT
fnp-2920	71	7	synuclein	synuclein	NOUN
fnp-2920	71	8	in	in	ADP
fnp-2920	71	9	lb	lb	NUM
fnp-2920	71	10	and	and	CCONJ
fnp-2920	71	11	ln	ln	ADJ
fnp-2920	71	12	was	be	AUX
fnp-2920	71	13	hyperphosphorylated	hyperphosphorylate	VERB
fnp-2920	71	14	at	at	ADP
fnp-2920	71	15	serine	serine	ADJ
fnp-2920	71	16	residue	residue	NOUN
fnp-2920	71	17	129	129	NUM
fnp-2920	71	18	[	[	X
fnp-2920	71	19	23	23	NUM
fnp-2920	71	20	]	]	PUNCT
fnp-2920	71	21	(	(	PUNCT
fnp-2920	71	22	figure	figure	NOUN
fnp-2920	71	23	2	2	NUM
fnp-2920	71	24	)	)	PUNCT
fnp-2920	71	25	.	.	PUNCT
fnp-2920	72	1	because	because	SCONJ
fnp-2920	72	2	alpha	alpha	NOUN
fnp-2920	72	3	and	and	CCONJ
fnp-2920	72	4	phospho	phospho	ADJ
fnp-2920	72	5	-	-	PUNCT
fnp-2920	72	6	alpha	alpha	NOUN
fnp-2920	72	7	-	-	PUNCT
fnp-2920	72	8	synuclein	synuclein	NOUN
fnp-2920	72	9	immunohistochemical	immunohistochemical	ADJ
fnp-2920	72	10	staining	staining	NOUN
fnp-2920	72	11	has	have	VERB
fnp-2920	72	12	a	a	DET
fnp-2920	72	13	much	much	ADV
fnp-2920	72	14	greater	great	ADJ
fnp-2920	72	15	sensitivity	sensitivity	NOUN
fnp-2920	72	16	than	than	ADP
fnp-2920	72	17	hematoxylin	hematoxylin	NOUN
fnp-2920	72	18	and	and	CCONJ
fnp-2920	72	19	eosin	eosin	NOUN
fnp-2920	72	20	staining	stain	VERB
fnp-2920	72	21	for	for	ADP
fnp-2920	72	22	the	the	DET
fnp-2920	72	23	detection	detection	NOUN
fnp-2920	72	24	of	of	ADP
fnp-2920	72	25	lb	lb	PRON
fnp-2920	72	26	[	[	X
fnp-2920	72	27	24	24	NUM
fnp-2920	72	28	]	]	PUNCT
fnp-2920	72	29	,	,	PUNCT
fnp-2920	72	30	this	this	DET
fnp-2920	72	31	method	method	NOUN
fnp-2920	72	32	quickly	quickly	ADV
fnp-2920	72	33	became	become	VERB
fnp-2920	72	34	the	the	DET
fnp-2920	72	35	method	method	NOUN
fnp-2920	72	36	of	of	ADP
fnp-2920	72	37	choice	choice	NOUN
fnp-2920	72	38	for	for	ADP
fnp-2920	72	39	the	the	DET
fnp-2920	72	40	neuropathological	neuropathological	ADJ
fnp-2920	72	41	diagnosis	diagnosis	NOUN
fnp-2920	72	42	of	of	ADP
fnp-2920	72	43	pd	pd	NOUN
fnp-2920	72	44	[	[	X
fnp-2920	72	45	25	25	NUM
fnp-2920	72	46	]	]	PUNCT
fnp-2920	72	47	.	.	PUNCT
fnp-2920	73	1	using	use	VERB
fnp-2920	73	2	this	this	DET
fnp-2920	73	3	approach	approach	NOUN
fnp-2920	73	4	,	,	PUNCT
fnp-2920	73	5	several	several	ADJ
fnp-2920	73	6	neuropathology	neuropathology	NOUN
fnp-2920	73	7	laboratories	laboratory	NOUN
fnp-2920	73	8	demonstrated	demonstrate	VERB
fnp-2920	73	9	that	that	SCONJ
fnp-2920	73	10	lb	lb	NUM
fnp-2920	73	11	and	and	CCONJ
fnp-2920	73	12	ln	ln	ADJ
fnp-2920	73	13	-	-	PUNCT
fnp-2920	73	14	like	like	ADJ
fnp-2920	73	15	structures	structure	NOUN
fnp-2920	73	16	were	be	AUX
fnp-2920	73	17	observed	observe	VERB
fnp-2920	73	18	in	in	ADP
fnp-2920	73	19	the	the	DET
fnp-2920	73	20	ens	ens	NOUN
fnp-2920	73	21	(	(	PUNCT
fnp-2920	73	22	in	in	ADP
fnp-2920	73	23	both	both	CCONJ
fnp-2920	73	24	the	the	DET
fnp-2920	73	25	myenteric	myenteric	ADJ
fnp-2920	73	26	and	and	CCONJ
fnp-2920	73	27	submucosal	submucosal	NOUN
fnp-2920	73	28	plexus	plexus	NOUN
fnp-2920	73	29	)	)	PUNCT
fnp-2920	73	30	in	in	ADP
fnp-2920	73	31	the	the	DET
fnp-2920	73	32	vast	vast	ADJ
fnp-2920	73	33	majority	majority	NOUN
fnp-2920	73	34	of	of	ADP
fnp-2920	73	35	pd	pd	PROPN
fnp-2920	73	36	patients	patient	NOUN
fnp-2920	73	37	[	[	X
fnp-2920	73	38	3–7	3–7	NOUN
fnp-2920	73	39	]	]	X
fnp-2920	73	40	(	(	PUNCT
fnp-2920	73	41	figure	figure	NOUN
fnp-2920	73	42	3	3	NUM
fnp-2920	73	43	)	)	PUNCT
fnp-2920	73	44	.	.	PUNCT
fnp-2920	74	1	in	in	ADP
fnp-2920	74	2	some	some	PRON
fnp-2920	74	3	of	of	ADP
fnp-2920	74	4	these	these	DET
fnp-2920	74	5	studies	study	NOUN
fnp-2920	74	6	,	,	PUNCT
fnp-2920	74	7	proteinase	proteinase	NOUN
fnp-2920	74	8	k	k	PROPN
fnp-2920	75	1	[	[	X
fnp-2920	75	2	3	3	NUM
fnp-2920	75	3	]	]	PUNCT
fnp-2920	75	4	or	or	CCONJ
fnp-2920	75	5	alkaline	alkaline	ADJ
fnp-2920	75	6	protease	protease	NOUN
fnp-2920	75	7	[	[	X
fnp-2920	75	8	7	7	NUM
fnp-2920	75	9	]	]	X
fnp-2920	75	10	pre	pre	NOUN
fnp-2920	75	11	-	-	NOUN
fnp-2920	75	12	treatments	treatment	NOUN
fnp-2920	75	13	were	be	AUX
fnp-2920	75	14	used	use	VERB
fnp-2920	75	15	primarily	primarily	ADV
fnp-2920	75	16	to	to	PART
fnp-2920	75	17	unmask	unmask	VERB
fnp-2920	75	18	antigens	antigen	NOUN
fnp-2920	75	19	and	and	CCONJ
fnp-2920	75	20	enhance	enhance	VERB
fnp-2920	75	21	immunolabeling	immunolabeling	NOUN
fnp-2920	75	22	,	,	PUNCT
fnp-2920	75	23	but	but	CCONJ
fnp-2920	75	24	such	such	ADJ
fnp-2920	75	25	treatments	treatment	NOUN
fnp-2920	75	26	might	might	AUX
fnp-2920	75	27	also	also	ADV
fnp-2920	75	28	allow	allow	VERB
fnp-2920	75	29	protease	protease	NOUN
fnp-2920	75	30	-	-	PUNCT
fnp-2920	75	31	resistant	resistant	ADJ
fnp-2920	75	32	misfolded	misfolded	NOUN
fnp-2920	75	33	,	,	PUNCT
fnp-2920	75	34	aggregated	aggregate	VERB
fnp-2920	75	35	and	and	CCONJ
fnp-2920	75	36	hyperphosphorylated	hyperphosphorylate	VERB
fnp-2920	75	37	alpha	alpha	NOUN
fnp-2920	75	38	-	-	PUNCT
fnp-2920	75	39	synuclein	synuclein	NOUN
fnp-2920	75	40	to	to	PART
fnp-2920	75	41	be	be	AUX
fnp-2920	75	42	distinguished	distinguish	VERB
fnp-2920	75	43	from	from	ADP
fnp-2920	75	44	soluble	soluble	ADJ
fnp-2920	75	45	forms	form	NOUN
fnp-2920	75	46	of	of	ADP
fnp-2920	75	47	the	the	DET
fnp-2920	75	48	protein	protein	NOUN
fnp-2920	75	49	.	.	PUNCT
fnp-2920	76	1	on	on	ADP
fnp-2920	76	2	the	the	DET
fnp-2920	76	3	whole	whole	NOUN
fnp-2920	76	4	these	these	DET
fnp-2920	76	5	findings	finding	NOUN
fnp-2920	76	6	suggest	suggest	VERB
fnp-2920	76	7	that	that	SCONJ
fnp-2920	76	8	pathological	pathological	ADJ
fnp-2920	76	9	aggregated	aggregate	VERB
fnp-2920	76	10	alpha	alpha	NOUN
fnp-2920	76	11	-	-	PUNCT
fnp-2920	76	12	synuclein	synuclein	NOUN
fnp-2920	76	13	is	be	AUX
fnp-2920	76	14	present	present	ADJ
fnp-2920	76	15	within	within	ADP
fnp-2920	76	16	the	the	DET
fnp-2920	76	17	gi	gi	PROPN
fnp-2920	76	18	tract	tract	NOUN
fnp-2920	76	19	of	of	ADP
fnp-2920	76	20	pd	pd	NOUN
fnp-2920	76	21	subjects	subject	NOUN
fnp-2920	76	22	.	.	PUNCT
fnp-2920	77	1	two	two	NUM
fnp-2920	77	2	key	key	ADJ
fnp-2920	77	3	issues	issue	NOUN
fnp-2920	77	4	should	should	AUX
fnp-2920	77	5	however	however	ADV
fnp-2920	77	6	be	be	AUX
fnp-2920	77	7	borne	bear	VERB
fnp-2920	77	8	in	in	ADP
fnp-2920	77	9	mind	mind	NOUN
fnp-2920	77	10	.	.	PUNCT
fnp-2920	78	1	first	first	ADV
fnp-2920	78	2	,	,	PUNCT
fnp-2920	78	3	the	the	DET
fnp-2920	78	4	mere	mere	ADJ
fnp-2920	78	5	detection	detection	NOUN
fnp-2920	78	6	of	of	ADP
fnp-2920	78	7	alpha	alpha	NOUN
fnp-2920	78	8	-	-	PUNCT
fnp-2920	78	9	synuclein	synuclein	NOUN
fnp-2920	78	10	phosphorylated	phosphorylate	VERB
fnp-2920	78	11	at	at	ADP
fnp-2920	78	12	serine	serine	NOUN
fnp-2920	78	13	129	129	NUM
fnp-2920	78	14	is	be	AUX
fnp-2920	78	15	not	not	PART
fnp-2920	78	16	synonymous	synonymous	ADJ
fnp-2920	78	17	with	with	ADP
fnp-2920	78	18	aggregation	aggregation	NOUN
fnp-2920	78	19	since	since	SCONJ
fnp-2920	78	20	soluble	soluble	ADJ
fnp-2920	78	21	alpha	alpha	NOUN
fnp-2920	78	22	-	-	PUNCT
fnp-2920	78	23	synuclein	synuclein	NOUN
fnp-2920	78	24	is	be	AUX
fnp-2920	78	25	also	also	ADV
fnp-2920	78	26	physiologically	physiologically	ADV
fnp-2920	78	27	phosphorylated	phosphorylate	VERB
fnp-2920	78	28	at	at	ADP
fnp-2920	78	29	this	this	DET
fnp-2920	78	30	residue	residue	NOUN
fnp-2920	78	31	[	[	X
fnp-2920	78	32	26	26	NUM
fnp-2920	78	33	]	]	PUNCT
fnp-2920	78	34	.	.	PUNCT
fnp-2920	79	1	secondly	secondly	ADV
fnp-2920	79	2	,	,	PUNCT
fnp-2920	79	3	immunohistochemical	immunohistochemical	ADJ
fnp-2920	79	4	approaches	approach	NOUN
fnp-2920	79	5	are	be	AUX
fnp-2920	79	6	not	not	PART
fnp-2920	79	7	sufficient	sufficient	ADJ
fnp-2920	79	8	to	to	PART
fnp-2920	79	9	show	show	VERB
fnp-2920	79	10	that	that	SCONJ
fnp-2920	79	11	alpha	alpha	NOUN
fnp-2920	79	12	-	-	PUNCT
fnp-2920	79	13	synuclein	synuclein	NOUN
fnp-2920	79	14	is	be	AUX
fnp-2920	79	15	misfolded	misfolde	VERB
fnp-2920	79	16	/	/	SYM
fnp-2920	79	17	aggregated	aggregate	VERB
fnp-2920	79	18	;	;	PUNCT
fnp-2920	79	19	biochemical	biochemical	ADJ
fnp-2920	79	20	confirmation	confirmation	NOUN
fnp-2920	79	21	of	of	ADP
fnp-2920	79	22	altered	altered	ADJ
fnp-2920	79	23	solubility	solubility	NOUN
fnp-2920	79	24	is	be	AUX
fnp-2920	79	25	required	require	VERB
fnp-2920	79	26	.	.	PUNCT
fnp-2920	80	1	indeed	indeed	ADV
fnp-2920	80	2	,	,	PUNCT
fnp-2920	80	3	in	in	ADP
fnp-2920	80	4	the	the	DET
fnp-2920	80	5	cns	cns	NOUN
fnp-2920	80	6	,	,	PUNCT
fnp-2920	80	7	a	a	DET
fnp-2920	80	8	comprehensive	comprehensive	ADJ
fnp-2920	80	9	biochemical	biochemical	ADJ
fnp-2920	80	10	characterisation	characterisation	NOUN
fnp-2920	80	11	of	of	ADP
fnp-2920	80	12	alpha	alpha	NOUN
fnp-2920	80	13	-	-	PUNCT
fnp-2920	80	14	synuclein	synuclein	NOUN
fnp-2920	80	15	forms	form	NOUN
fnp-2920	80	16	in	in	ADP
fnp-2920	80	17	lb	lb	NUM
fnp-2920	80	18	has	have	AUX
fnp-2920	80	19	already	already	ADV
fnp-2920	80	20	been	be	AUX
fnp-2920	80	21	carried	carry	VERB
fnp-2920	80	22	out	out	ADP
fnp-2920	80	23	.	.	PUNCT
fnp-2920	81	1	using	use	VERB
fnp-2920	81	2	one	one	NUM
fnp-2920	81	3	and	and	CCONJ
fnp-2920	81	4	two	two	NUM
fnp-2920	81	5	-	-	PUNCT
fnp-2920	81	6	dimensional	dimensional	ADJ
fnp-2920	81	7	immunoblot	immunoblot	NOUN
fnp-2920	81	8	analysis	analysis	NOUN
fnp-2920	81	9	with	with	ADP
fnp-2920	81	10	modification	modification	NOUN
fnp-2920	81	11	-	-	PUNCT
fnp-2920	81	12	specific	specific	ADJ
fnp-2920	81	13	synuclein	synuclein	NOUN
fnp-2920	81	14	antibodies	antibody	NOUN
fnp-2920	81	15	and	and	CCONJ
fnp-2920	81	16	mass	mass	NOUN
fnp-2920	81	17	spectroscopy	spectroscopy	NOUN
fnp-2920	81	18	,	,	PUNCT
fnp-2920	81	19	anderson	anderson	PROPN
fnp-2920	81	20	et	et	PROPN
fnp-2920	81	21	al	al	PROPN
fnp-2920	81	22	.	.	PROPN
fnp-2920	81	23	confirmed	confirm	VERB
fnp-2920	81	24	that	that	SCONJ
fnp-2920	81	25	the	the	DET
fnp-2920	81	26	predominant	predominant	ADJ
fnp-2920	81	27	modification	modification	NOUN
fnp-2920	81	28	of	of	ADP
fnp-2920	81	29	alpha	alpha	NOUN
fnp-2920	81	30	-	-	PUNCT
fnp-2920	81	31	synuclein	synuclein	NOUN
fnp-2920	81	32	in	in	ADP
fnp-2920	81	33	lb	lb	NUM
fnp-2920	81	34	was	be	AUX
fnp-2920	81	35	phosphorylation	phosphorylation	NOUN
fnp-2920	81	36	at	at	ADP
fnp-2920	81	37	serine	serine	NOUN
fnp-2920	81	38	129	129	NUM
fnp-2920	81	39	.	.	PUNCT
fnp-2920	82	1	they	they	PRON
fnp-2920	82	2	also	also	ADV
fnp-2920	82	3	found	find	VERB
fnp-2920	82	4	a	a	DET
fnp-2920	82	5	set	set	NOUN
fnp-2920	82	6	of	of	ADP
fnp-2920	82	7	additional	additional	ADJ
fnp-2920	82	8	characteristic	characteristic	ADJ
fnp-2920	82	9	modifications	modification	NOUN
fnp-2920	82	10	including	include	VERB
fnp-2920	82	11	ubiquitination	ubiquitination	NOUN
fnp-2920	82	12	at	at	ADP
fnp-2920	82	13	amino	amino	NOUN
fnp-2920	82	14	-	-	PUNCT
fnp-2920	82	15	terminal	terminal	ADJ
fnp-2920	82	16	lysine	lysine	NOUN
fnp-2920	82	17	residues	residue	NOUN
fnp-2920	82	18	and	and	CCONJ
fnp-2920	82	19	specific	specific	ADJ
fnp-2920	82	20	carboxy	carboxy	ADJ
fnp-2920	82	21	-	-	PUNCT
fnp-2920	82	22	terminal	terminal	ADJ
fnp-2920	82	23	truncations	truncation	NOUN
fnp-2920	82	24	[	[	X
fnp-2920	82	25	27	27	NUM
fnp-2920	82	26	]	]	PUNCT
fnp-2920	82	27	(	(	PUNCT
fnp-2920	82	28	figure	figure	NOUN
fnp-2920	82	29	2	2	NUM
fnp-2920	82	30	)	)	PUNCT
fnp-2920	82	31	.	.	PUNCT
fnp-2920	83	1	an	an	DET
fnp-2920	83	2	additional	additional	ADJ
fnp-2920	83	3	property	property	NOUN
fnp-2920	83	4	of	of	ADP
fnp-2920	83	5	alpha	alpha	NOUN
fnp-2920	83	6	-	-	PUNCT
fnp-2920	83	7	synuclein	synuclein	NOUN
fnp-2920	83	8	aggregates	aggregate	NOUN
fnp-2920	83	9	found	find	VERB
fnp-2920	83	10	in	in	ADP
fnp-2920	83	11	diseased	diseased	ADJ
fnp-2920	83	12	brains	brain	NOUN
fnp-2920	83	13	is	be	AUX
fnp-2920	83	14	their	their	PRON
fnp-2920	83	15	seeding	seeding	NOUN
fnp-2920	83	16	ability	ability	NOUN
fnp-2920	83	17	:	:	PUNCT
fnp-2920	83	18	the	the	DET
fnp-2920	83	19	amyloid	amyloid	NOUN
fnp-2920	83	20	fibrils	fibril	NOUN
fnp-2920	83	21	formed	form	VERB
fnp-2920	83	22	by	by	ADP
fnp-2920	83	23	alpha	alpha	NOUN
fnp-2920	83	24	-	-	PUNCT
fnp-2920	83	25	synuclein	synuclein	NOUN
fnp-2920	83	26	aggregates	aggregate	NOUN
fnp-2920	83	27	can	can	AUX
fnp-2920	83	28	act	act	VERB
fnp-2920	83	29	as	as	ADP
fnp-2920	83	30	templates	template	NOUN
fnp-2920	83	31	for	for	ADP
fnp-2920	83	32	the	the	DET
fnp-2920	83	33	conversion	conversion	NOUN
fnp-2920	83	34	of	of	ADP
fnp-2920	83	35	physiological	physiological	ADJ
fnp-2920	83	36	alpha	alpha	NOUN
fnp-2920	83	37	-	-	PUNCT
fnp-2920	83	38	synuclein	synuclein	NOUN
fnp-2920	83	39	,	,	PUNCT
fnp-2920	83	40	resulting	result	VERB
fnp-2920	83	41	in	in	ADP
fnp-2920	83	42	the	the	DET
fnp-2920	83	43	growth	growth	NOUN
fnp-2920	83	44	of	of	ADP
fnp-2920	83	45	the	the	DET
fnp-2920	83	46	fibrils	fibril	NOUN
fnp-2920	83	47	and	and	CCONJ
fnp-2920	83	48	spread	spread	VERB
fnp-2920	83	49	of	of	ADP
fnp-2920	83	50	alpha	alpha	NOUN
fnp-2920	83	51	-	-	PUNCT
fnp-2920	83	52	synuclein	synuclein	NOUN
fnp-2920	83	53	pathology	pathology	NOUN
fnp-2920	83	54	[	[	X
fnp-2920	83	55	28	28	NUM
fnp-2920	83	56	]	]	PUNCT
fnp-2920	83	57	.	.	PUNCT
fnp-2920	84	1	how	how	SCONJ
fnp-2920	84	2	about	about	ADP
fnp-2920	84	3	the	the	DET
fnp-2920	84	4	biochemical	biochemical	ADJ
fnp-2920	84	5	characterisation	characterisation	NOUN
fnp-2920	84	6	of	of	ADP
fnp-2920	84	7	alpha	alpha	NOUN
fnp-2920	84	8	-	-	PUNCT
fnp-2920	84	9	synuclein	synuclein	NOUN
fnp-2920	84	10	in	in	ADP
fnp-2920	84	11	diseased	diseased	ADJ
fnp-2920	84	12	ens	ens	NOUN
fnp-2920	84	13	?	?	PUNCT
fnp-2920	85	1	there	there	PRON
fnp-2920	85	2	are	be	VERB
fnp-2920	85	3	some	some	DET
fnp-2920	85	4	existing	exist	VERB
fnp-2920	85	5	data	datum	NOUN
fnp-2920	85	6	but	but	CCONJ
fnp-2920	85	7	it	it	PRON
fnp-2920	85	8	is	be	AUX
fnp-2920	85	9	definitely	definitely	ADV
fnp-2920	85	10	less	less	ADV
fnp-2920	85	11	complete	complete	ADJ
fnp-2920	85	12	and	and	CCONJ
fnp-2920	85	13	robust	robust	ADJ
fnp-2920	85	14	than	than	ADP
fnp-2920	85	15	those	those	PRON
fnp-2920	85	16	available	available	ADJ
fnp-2920	85	17	for	for	ADP
fnp-2920	85	18	the	the	DET
fnp-2920	85	19	cns	cns	NOUN
fnp-2920	85	20	.	.	PUNCT
fnp-2920	86	1	using	use	VERB
fnp-2920	86	2	one	one	NUM
fnp-2920	86	3	and	and	CCONJ
fnp-2920	86	4	two	two	NUM
fnp-2920	86	5	-	-	PUNCT
fnp-2920	86	6	dimensional	dimensional	ADJ
fnp-2920	86	7	analysis	analysis	NOUN
fnp-2920	86	8	of	of	ADP
fnp-2920	86	9	colonic	colonic	ADJ
fnp-2920	86	10	biopsies	biopsy	NOUN
fnp-2920	86	11	,	,	PUNCT
fnp-2920	86	12	we	we	PRON
fnp-2920	86	13	were	be	AUX
fnp-2920	86	14	unable	unable	ADJ
fnp-2920	86	15	to	to	PART
fnp-2920	86	16	detect	detect	VERB
fnp-2920	86	17	any	any	DET
fnp-2920	86	18	differences	difference	NOUN
fnp-2920	86	19	in	in	ADP
fnp-2920	86	20	the	the	DET
fnp-2920	86	21	expression	expression	NOUN
fnp-2920	86	22	levels	level	NOUN
fnp-2920	86	23	,	,	PUNCT
fnp-2920	86	24	phosphorylation	phosphorylation	NOUN
fnp-2920	86	25	or	or	CCONJ
fnp-2920	86	26	aggregation	aggregation	NOUN
fnp-2920	86	27	status	status	NOUN
fnp-2920	86	28	of	of	ADP
fnp-2920	86	29	alpha	alpha	NOUN
fnp-2920	86	30	-	-	PUNCT
fnp-2920	86	31	synuclein	synuclein	NOUN
fnp-2920	86	32	between	between	ADP
fnp-2920	86	33	controls	control	NOUN
fnp-2920	86	34	and	and	CCONJ
fnp-2920	86	35	pd	pd	NOUN
fnp-2920	86	36	specimens	specimen	NOUN
fnp-2920	86	37	[	[	X
fnp-2920	86	38	29	29	NUM
fnp-2920	86	39	]	]	PUNCT
fnp-2920	86	40	.	.	PUNCT
fnp-2920	87	1	these	these	DET
fnp-2920	87	2	negative	negative	ADJ
fnp-2920	87	3	findings	finding	NOUN
fnp-2920	87	4	might	might	AUX
fnp-2920	87	5	however	however	ADV
fnp-2920	87	6	be	be	AUX
fnp-2920	87	7	explained	explain	VERB
fnp-2920	87	8	by	by	ADP
fnp-2920	87	9	the	the	DET
fnp-2920	87	10	relative	relative	ADJ
fnp-2920	87	11	sparsity	sparsity	NOUN
fnp-2920	87	12	of	of	ADP
fnp-2920	87	13	neuronal	neuronal	ADJ
fnp-2920	87	14	structures	structure	NOUN
fnp-2920	87	15	and/or	and/or	CCONJ
fnp-2920	87	16	alpha	alpha	NOUN
fnp-2920	87	17	-	-	PUNCT
fnp-2920	87	18	synuclein	synuclein	NOUN
fnp-2920	87	19	inclusions	inclusion	NOUN
fnp-2920	87	20	in	in	ADP
fnp-2920	87	21	the	the	DET
fnp-2920	87	22	gi	gi	NOUN
fnp-2920	87	23	samples	sample	NOUN
fnp-2920	87	24	that	that	PRON
fnp-2920	87	25	were	be	AUX
fnp-2920	87	26	used	use	VERB
fnp-2920	87	27	;	;	PUNCT
fnp-2920	87	28	due	due	ADP
fnp-2920	87	29	to	to	ADP
fnp-2920	87	30	a	a	DET
fnp-2920	87	31	shortage	shortage	NOUN
fnp-2920	87	32	of	of	ADP
fnp-2920	87	33	samples	sample	NOUN
fnp-2920	87	34	,	,	PUNCT
fnp-2920	87	35	only	only	ADV
fnp-2920	87	36	2	2	NUM
fnp-2920	87	37	routine	routine	ADJ
fnp-2920	87	38	colonic	colonic	NOUN
fnp-2920	87	39	biopsies	biopsy	NOUN
fnp-2920	87	40	per	per	ADP
fnp-2920	87	41	subject	subject	NOUN
fnp-2920	87	42	were	be	AUX
fnp-2920	87	43	pooled	pool	VERB
fnp-2920	87	44	and	and	CCONJ
fnp-2920	87	45	analysed	analyse	VERB
fnp-2920	87	46	.	.	PUNCT
fnp-2920	88	1	however	however	ADV
fnp-2920	88	2	,	,	PUNCT
fnp-2920	88	3	when	when	SCONJ
fnp-2920	88	4	we	we	PRON
fnp-2920	88	5	had	have	VERB
fnp-2920	88	6	the	the	DET
fnp-2920	88	7	opportunity	opportunity	NOUN
fnp-2920	88	8	to	to	PART
fnp-2920	88	9	analyse	analyse	VERB
fnp-2920	88	10	4	4	NUM
fnp-2920	88	11	pooled	pool	VERB
fnp-2920	88	12	biopsies	biopsy	NOUN
fnp-2920	88	13	per	per	ADP
fnp-2920	88	14	subject	subject	NOUN
fnp-2920	88	15	,	,	PUNCT
fnp-2920	88	16	we	we	PRON
fnp-2920	88	17	were	be	AUX
fnp-2920	88	18	able	able	ADJ
fnp-2920	88	19	to	to	PART
fnp-2920	88	20	detect	detect	VERB
fnp-2920	88	21	acidic	acidic	ADJ
fnp-2920	88	22	and	and	CCONJ
fnp-2920	88	23	high	high	ADJ
fnp-2920	88	24	molecular	molecular	ADJ
fnp-2920	88	25	weight	weight	NOUN
fnp-2920	88	26	alpha	alpha	NOUN
fnp-2920	88	27	-	-	PUNCT
fnp-2920	88	28	synuclein	synuclein	NOUN
fnp-2920	88	29	species	specie	NOUN
fnp-2920	88	30	in	in	ADP
fnp-2920	88	31	the	the	DET
fnp-2920	88	32	gi	gi	NOUN
fnp-2920	88	33	tract	tract	NOUN
fnp-2920	88	34	of	of	ADP
fnp-2920	88	35	pd	pd	NOUN
fnp-2920	88	36	patients	patient	NOUN
fnp-2920	88	37	but	but	CCONJ
fnp-2920	88	38	not	not	PART
fnp-2920	88	39	controls	control	NOUN
fnp-2920	88	40	,	,	PUNCT
fnp-2920	88	41	which	which	PRON
fnp-2920	88	42	likely	likely	ADV
fnp-2920	88	43	represent	represent	VERB
fnp-2920	88	44	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-2920	88	45	and	and	CCONJ
fnp-2920	88	46	aggregated	aggregate	VERB
fnp-2920	88	47	forms	form	NOUN
fnp-2920	88	48	of	of	ADP
fnp-2920	88	49	the	the	DET
fnp-2920	88	50	protein	protein	NOUN
fnp-2920	88	51	,	,	PUNCT
fnp-2920	88	52	respectively	respectively	ADV
fnp-2920	88	53	(	(	PUNCT
fnp-2920	88	54	lebouvier	lebouvier	ADV
fnp-2920	88	55	-	-	PUNCT
fnp-2920	88	56	derkinderen	derkinderen	NOUN
fnp-2920	88	57	unpublished	unpublished	ADJ
fnp-2920	88	58	results	result	NOUN
fnp-2920	88	59	,	,	PUNCT
fnp-2920	88	60	figure	figure	NOUN
fnp-2920	88	61	4	4	NUM
fnp-2920	88	62	)	)	PUNCT
fnp-2920	88	63	.	.	PUNCT
fnp-2920	89	1	such	such	DET
fnp-2920	89	2	a	a	DET
fnp-2920	89	3	pattern	pattern	NOUN
fnp-2920	89	4	is	be	AUX
fnp-2920	89	5	reminiscent	reminiscent	ADJ
fnp-2920	89	6	of	of	ADP
fnp-2920	89	7	that	that	PRON
fnp-2920	89	8	observed	observe	VERB
fnp-2920	89	9	in	in	ADP
fnp-2920	89	10	pd	pd	PROPN
fnp-2920	89	11	brain	brain	NOUN
fnp-2920	89	12	[	[	X
fnp-2920	89	13	27	27	NUM
fnp-2920	89	14	]	]	PUNCT
fnp-2920	89	15	(	(	PUNCT
fnp-2920	89	16	figure	figure	NOUN
fnp-2920	89	17	4	4	NUM
fnp-2920	89	18	)	)	PUNCT
fnp-2920	89	19	.	.	PUNCT
fnp-2920	90	1	the	the	DET
fnp-2920	90	2	limitations	limitation	NOUN
fnp-2920	90	3	of	of	ADP
fnp-2920	90	4	the	the	DET
fnp-2920	90	5	two	two	NUM
fnp-2920	90	6	-	-	PUNCT
fnp-2920	90	7	dimensional	dimensional	ADJ
fnp-2920	90	8	immunoblotting	immunoblotte	VERB
fnp-2920	90	9	technique	technique	NOUN
fnp-2920	90	10	prompted	prompt	VERB
fnp-2920	90	11	us	we	PRON
fnp-2920	90	12	to	to	PART
fnp-2920	90	13	use	use	VERB
fnp-2920	90	14	more	more	ADV
fnp-2920	90	15	sensitive	sensitive	ADJ
fnp-2920	90	16	approaches	approach	NOUN
fnp-2920	90	17	,	,	PUNCT
fnp-2920	90	18	based	base	VERB
fnp-2920	90	19	on	on	ADP
fnp-2920	90	20	the	the	DET
fnp-2920	90	21	seeding	seed	VERB
fnp-2920	90	22	efficiency	efficiency	NOUN
fnp-2920	90	23	of	of	ADP
fnp-2920	90	24	alpha	alpha	NOUN
fnp-2920	90	25	-	-	PUNCT
fnp-2920	90	26	synuclein	synuclein	NOUN
fnp-2920	90	27	.	.	PUNCT
fnp-2920	91	1	using	use	VERB
fnp-2920	91	2	an	an	DET
fnp-2920	91	3	assay	assay	NOUN
fnp-2920	91	4	inspired	inspire	VERB
fnp-2920	91	5	by	by	ADP
fnp-2920	91	6	the	the	DET
fnp-2920	91	7	protein	protein	NOUN
fnp-2920	91	8	misfolding	misfolde	VERB
fnp-2920	91	9	cyclic	cyclic	ADJ
fnp-2920	91	10	amplification	amplification	NOUN
fnp-2920	91	11	(	(	PUNCT
fnp-2920	91	12	pmca	pmca	NOUN
fnp-2920	91	13	)	)	PUNCT
fnp-2920	91	14	assay	assay	PROPN
fnp-2920	91	15	,	,	PUNCT
fnp-2920	91	16	we	we	PRON
fnp-2920	91	17	showed	show	VERB
fnp-2920	91	18	that	that	SCONJ
fnp-2920	91	19	gi	gi	NOUN
fnp-2920	91	20	biopsies	biopsy	NOUN
fnp-2920	91	21	from	from	ADP
fnp-2920	91	22	pd	pd	PROPN
fnp-2920	91	23	patients	patient	NOUN
fnp-2920	91	24	(	(	PUNCT
fnp-2920	91	25	2	2	NUM
fnp-2920	91	26	to	to	PART
fnp-2920	91	27	4	4	NUM
fnp-2920	91	28	biopsies	biopsy	NOUN
fnp-2920	91	29	per	per	ADP
fnp-2920	91	30	subject	subject	NOUN
fnp-2920	91	31	taken	take	VERB
fnp-2920	91	32	from	from	ADP
fnp-2920	91	33	the	the	DET
fnp-2920	91	34	upper	upper	ADJ
fnp-2920	91	35	or	or	CCONJ
fnp-2920	91	36	lower	low	ADJ
fnp-2920	91	37	gi	gi	NOUN
fnp-2920	91	38	tract	tract	NOUN
fnp-2920	91	39	)	)	PUNCT
fnp-2920	91	40	seeded	seed	VERB
fnp-2920	91	41	alpha	alpha	NOUN
fnp-2920	91	42	-	-	PUNCT
fnp-2920	91	43	synuclein	synuclein	NOUN
fnp-2920	91	44	aggregation	aggregation	NOUN
fnp-2920	91	45	in	in	ADP
fnp-2920	91	46	10	10	NUM
fnp-2920	91	47	out	out	ADP
fnp-2920	91	48	of	of	ADP
fnp-2920	91	49	18	18	NUM
fnp-2920	91	50	cases	case	NOUN
fnp-2920	91	51	[	[	X
fnp-2920	91	52	30	30	NUM
fnp-2920	91	53	]	]	PUNCT
fnp-2920	91	54	.	.	PUNCT
fnp-2920	92	1	more	more	ADV
fnp-2920	92	2	recently	recently	ADV
fnp-2920	92	3	,	,	PUNCT
fnp-2920	92	4	viviane	viviane	PROPN
fnp-2920	92	5	labrie	labrie	PROPN
fnp-2920	92	6	and	and	CCONJ
fnp-2920	92	7	patrik	patrik	PROPN
fnp-2920	92	8	brundin	brundin	PROPN
fnp-2920	92	9	’s	’s	PART
fnp-2920	92	10	group	group	NOUN
fnp-2920	92	11	focused	focus	VERB
fnp-2920	92	12	on	on	ADP
fnp-2920	92	13	the	the	DET
fnp-2920	92	14	vermiform	vermiform	NOUN
fnp-2920	92	15	appendix	appendix	NOUN
fnp-2920	92	16	,	,	PUNCT
fnp-2920	92	17	a	a	DET
fnp-2920	92	18	structure	structure	NOUN
fnp-2920	92	19	which	which	PRON
fnp-2920	92	20	is	be	AUX
fnp-2920	92	21	particularly	particularly	ADV
fnp-2920	92	22	enriched	enrich	VERB
fnp-2920	92	23	in	in	ADP
fnp-2920	92	24	alpha	alpha	NOUN
fnp-2920	92	25	-	-	PUNCT
fnp-2920	92	26	synuclein	synuclein	NOUN
fnp-2920	92	27	[	[	X
fnp-2920	92	28	31	31	NUM
fnp-2920	92	29	]	]	PUNCT
fnp-2920	92	30	.	.	PUNCT
fnp-2920	93	1	using	use	VERB
fnp-2920	93	2	mass	mass	ADJ
fnp-2920	93	3	spectrometry	spectrometry	NOUN
fnp-2920	93	4	,	,	PUNCT
fnp-2920	93	5	they	they	PRON
fnp-2920	93	6	identified	identify	VERB
fnp-2920	93	7	full	full	ADJ
fnp-2920	93	8	-	-	PUNCT
fnp-2920	93	9	length	length	NOUN
fnp-2920	93	10	alpha	alpha	NOUN
fnp-2920	93	11	-	-	PUNCT
fnp-2920	93	12	synuclein	synuclein	NOUN
fnp-2920	93	13	together	together	ADV
fnp-2920	93	14	with	with	ADP
fnp-2920	93	15	a	a	DET
fnp-2920	93	16	set	set	NOUN
fnp-2920	93	17	of	of	ADP
fnp-2920	93	18	10	10	NUM
fnp-2920	93	19	truncated	truncated	ADJ
fnp-2920	93	20	forms	form	NOUN
fnp-2920	93	21	in	in	ADP
fnp-2920	93	22	the	the	DET
fnp-2920	93	23	healthy	healthy	ADJ
fnp-2920	93	24	human	human	ADJ
fnp-2920	93	25	appendix	appendix	NOUN
fnp-2920	93	26	[	[	X
fnp-2920	93	27	32	32	NUM
fnp-2920	93	28	]	]	PUNCT
fnp-2920	93	29	.	.	PUNCT
fnp-2920	94	1	additional	additional	ADJ
fnp-2920	94	2	experiments	experiment	NOUN
fnp-2920	94	3	performed	perform	VERB
fnp-2920	94	4	with	with	ADP
fnp-2920	94	5	an	an	DET
fnp-2920	94	6	in	in	ADP
fnp-2920	94	7	vitro	vitro	X
fnp-2920	94	8	shaking	shake	VERB
fnp-2920	94	9	assay	assay	ADV
fnp-2920	94	10	(	(	PUNCT
fnp-2920	94	11	also	also	ADV
fnp-2920	94	12	inspired	inspire	VERB
fnp-2920	94	13	by	by	ADP
fnp-2920	94	14	the	the	DET
fnp-2920	94	15	pmca	pmca	NOUN
fnp-2920	94	16	approach	approach	NOUN
fnp-2920	94	17	)	)	PUNCT
fnp-2920	94	18	,	,	PUNCT
fnp-2920	94	19	showed	show	VERB
fnp-2920	94	20	that	that	SCONJ
fnp-2920	94	21	appendix	appendix	ADJ
fnp-2920	94	22	lysates	lysate	NOUN
fnp-2920	94	23	from	from	ADP
fnp-2920	94	24	either	either	CCONJ
fnp-2920	94	25	control	control	NOUN
fnp-2920	94	26	or	or	CCONJ
fnp-2920	94	27	pd	pd	NOUN
fnp-2920	94	28	subjects	subject	NOUN
fnp-2920	94	29	seeded	seed	VERB
fnp-2920	94	30	aggregation	aggregation	NOUN
fnp-2920	94	31	and	and	CCONJ
fnp-2920	94	32	truncation	truncation	NOUN
fnp-2920	94	33	of	of	ADP
fnp-2920	94	34	alpha	alpha	NOUN
fnp-2920	94	35	-	-	PUNCT
fnp-2920	94	36	synuclein	synuclein	NOUN
fnp-2920	94	37	.	.	PUNCT
fnp-2920	95	1	these	these	DET
fnp-2920	95	2	intriguing	intriguing	ADJ
fnp-2920	95	3	and	and	CCONJ
fnp-2920	95	4	provocative	provocative	ADJ
fnp-2920	95	5	findings	finding	NOUN
fnp-2920	95	6	suggest	suggest	VERB
fnp-2920	95	7	that	that	SCONJ
fnp-2920	95	8	aggregated	aggregate	VERB
fnp-2920	95	9	and	and	CCONJ
fnp-2920	95	10	truncated	truncated	ADJ
fnp-2920	95	11	alpha	alpha	NOUN
fnp-2920	95	12	-	-	PUNCT
fnp-2920	95	13	synuclein	synuclein	NOUN
fnp-2920	95	14	are	be	AUX
fnp-2920	95	15	consistently	consistently	ADV
fnp-2920	95	16	found	find	VERB
fnp-2920	95	17	in	in	ADP
fnp-2920	95	18	the	the	DET
fnp-2920	95	19	human	human	ADJ
fnp-2920	95	20	healthy	healthy	ADJ
fnp-2920	95	21	appendix	appendix	NOUN
fnp-2920	95	22	,	,	PUNCT
fnp-2920	95	23	thereby	thereby	ADV
fnp-2920	95	24	supporting	support	VERB
fnp-2920	95	25	the	the	DET
fnp-2920	95	26	assumption	assumption	NOUN
fnp-2920	95	27	that	that	SCONJ
fnp-2920	95	28	the	the	DET
fnp-2920	95	29	appendix	appendix	NOUN
fnp-2920	95	30	may	may	AUX
fnp-2920	95	31	act	act	VERB
fnp-2920	95	32	as	as	ADP
fnp-2920	95	33	a	a	DET
fnp-2920	95	34	reservoir	reservoir	NOUN
fnp-2920	95	35	for	for	ADP
fnp-2920	95	36	pathogenic	pathogenic	ADJ
fnp-2920	95	37	forms	form	NOUN
fnp-2920	95	38	of	of	ADP
fnp-2920	95	39	alpha	alpha	NOUN
fnp-2920	95	40	-	-	PUNCT
fnp-2920	95	41	synuclein	synuclein	NOUN
fnp-2920	96	1	[	[	X
fnp-2920	96	2	31	31	NUM
fnp-2920	96	3	,	,	PUNCT
fnp-2920	96	4	32	32	NUM
fnp-2920	96	5	]	]	PUNCT
fnp-2920	96	6	.	.	PUNCT
fnp-2920	97	1	figure	figure	VERB
fnp-2920	97	2	4	4	NUM
fnp-2920	97	3	.	.	PUNCT
fnp-2920	97	4	high	high	ADJ
fnp-2920	97	5	molecular	molecular	ADJ
fnp-2920	97	6	weight	weight	NOUN
fnp-2920	97	7	and	and	CCONJ
fnp-2920	97	8	post	post	ADJ
fnp-2920	97	9	-	-	ADJ
fnp-2920	97	10	translationally	translationally	ADV
fnp-2920	97	11	modified	modify	VERB
fnp-2920	97	12	alpha	alpha	NOUN
fnp-2920	97	13	-	-	PUNCT
fnp-2920	97	14	synuclein	synuclein	NOUN
fnp-2920	97	15	species	specie	NOUN
fnp-2920	97	16	in	in	ADP
fnp-2920	97	17	the	the	DET
fnp-2920	97	18	gi	gi	NOUN
fnp-2920	97	19	tract	tract	NOUN
fnp-2920	97	20	of	of	ADP
fnp-2920	97	21	pd	pd	PROPN
fnp-2920	97	22	patients	patient	NOUN
fnp-2920	97	23	.	.	PUNCT
fnp-2920	98	1	immunoblots	immunoblot	NOUN
fnp-2920	98	2	of	of	ADP
fnp-2920	98	3	total	total	ADJ
fnp-2920	98	4	mesencephalon	mesencephalon	NOUN
fnp-2920	98	5	lysates	lysate	NOUN
fnp-2920	98	6	(	(	PUNCT
fnp-2920	98	7	a	a	PRON
fnp-2920	98	8	and	and	CCONJ
fnp-2920	98	9	b	b	NOUN
fnp-2920	98	10	)	)	PUNCT
fnp-2920	98	11	from	from	ADP
fnp-2920	98	12	a	a	DET
fnp-2920	98	13	control	control	NOUN
fnp-2920	98	14	(	(	PUNCT
fnp-2920	98	15	a	a	NOUN
fnp-2920	98	16	)	)	PUNCT
fnp-2920	98	17	and	and	CCONJ
fnp-2920	98	18	a	a	DET
fnp-2920	98	19	pd	pd	NOUN
fnp-2920	98	20	patient	patient	ADJ
fnp-2920	98	21	autopsy	autopsy	ADJ
fnp-2920	98	22	sample	sample	NOUN
fnp-2920	98	23	(	(	PUNCT
fnp-2920	98	24	b	b	NOUN
fnp-2920	98	25	)	)	PUNCT
fnp-2920	98	26	,	,	PUNCT
fnp-2920	98	27	and	and	CCONJ
fnp-2920	98	28	immunoblots	immunoblot	NOUN
fnp-2920	98	29	of	of	ADP
fnp-2920	98	30	colonic	colonic	ADJ
fnp-2920	98	31	biopsy	biopsy	NOUN
fnp-2920	98	32	lysates	lysate	NOUN
fnp-2920	98	33	(	(	PUNCT
fnp-2920	98	34	c	c	NOUN
fnp-2920	98	35	and	and	CCONJ
fnp-2920	98	36	d	d	NOUN
fnp-2920	98	37	)	)	PUNCT
fnp-2920	98	38	from	from	ADP
fnp-2920	98	39	a	a	DET
fnp-2920	98	40	control	control	NOUN
fnp-2920	98	41	(	(	PUNCT
fnp-2920	98	42	c	c	NOUN
fnp-2920	98	43	)	)	PUNCT
fnp-2920	98	44	and	and	CCONJ
fnp-2920	98	45	pd	pd	PROPN
fnp-2920	98	46	patient	patient	NOUN
fnp-2920	98	47	(	(	PUNCT
fnp-2920	98	48	d	d	NOUN
fnp-2920	98	49	)	)	PUNCT
fnp-2920	98	50	were	be	AUX
fnp-2920	98	51	resolved	resolve	VERB
fnp-2920	98	52	by	by	ADP
fnp-2920	98	53	two	two	NUM
fnp-2920	98	54	-	-	PUNCT
fnp-2920	98	55	dimensional	dimensional	ADJ
fnp-2920	98	56	page	page	NOUN
fnp-2920	98	57	using	use	VERB
fnp-2920	98	58	ph	ph	ADJ
fnp-2920	98	59	3–10	3–10	NOUN
fnp-2920	98	60	ief	ief	NOUN
fnp-2920	98	61	gradients	gradient	NOUN
fnp-2920	98	62	.	.	PUNCT
fnp-2920	99	1	immunoblots	immunoblot	NOUN
fnp-2920	99	2	were	be	AUX
fnp-2920	99	3	probed	probe	VERB
fnp-2920	99	4	with	with	ADP
fnp-2920	99	5	the	the	DET
fnp-2920	99	6	alpha	alpha	NOUN
fnp-2920	99	7	-	-	PUNCT
fnp-2920	99	8	synuclein	synuclein	NOUN
fnp-2920	99	9	antibody	antibody	NOUN
fnp-2920	99	10	syn-1	syn-1	NOUN
fnp-2920	99	11	.	.	PUNCT
fnp-2920	100	1	white	white	ADJ
fnp-2920	100	2	asterisks	asterisk	NOUN
fnp-2920	100	3	mark	mark	VERB
fnp-2920	100	4	full	full	ADJ
fnp-2920	100	5	-	-	PUNCT
fnp-2920	100	6	length	length	NOUN
fnp-2920	100	7	synuclein	synuclein	NOUN
fnp-2920	100	8	.	.	PUNCT
fnp-2920	101	1	boxes	box	NOUN
fnp-2920	101	2	highlight	highlight	VERB
fnp-2920	101	3	differences	difference	NOUN
fnp-2920	101	4	between	between	ADP
fnp-2920	101	5	pd	pd	NOUN
fnp-2920	101	6	patients	patient	NOUN
fnp-2920	101	7	and	and	CCONJ
fnp-2920	101	8	controls	control	NOUN
fnp-2920	101	9	:	:	PUNCT
fnp-2920	101	10	acidic	acidic	ADJ
fnp-2920	101	11	modifications	modification	NOUN
fnp-2920	101	12	of	of	ADP
fnp-2920	101	13	full	full	ADJ
fnp-2920	101	14	-	-	PUNCT
fnp-2920	101	15	length	length	NOUN
fnp-2920	101	16	monomer	monomer	NOUN
fnp-2920	101	17	(	(	PUNCT
fnp-2920	101	18	solid	solid	ADJ
fnp-2920	101	19	boxes	box	NOUN
fnp-2920	101	20	)	)	PUNCT
fnp-2920	101	21	,	,	PUNCT
fnp-2920	101	22	and	and	CCONJ
fnp-2920	101	23	high	high	ADJ
fnp-2920	101	24	molecular	molecular	ADJ
fnp-2920	101	25	weight	weight	NOUN
fnp-2920	101	26	species	specie	NOUN
fnp-2920	101	27	(	(	PUNCT
fnp-2920	101	28	dotted	dot	VERB
fnp-2920	101	29	boxes	box	NOUN
fnp-2920	101	30	)	)	PUNCT
fnp-2920	101	31	are	be	AUX
fnp-2920	101	32	present	present	ADJ
fnp-2920	101	33	in	in	ADP
fnp-2920	101	34	pd	pd	PROPN
fnp-2920	101	35	patients	patient	NOUN
fnp-2920	101	36	and	and	CCONJ
fnp-2920	101	37	absent	absent	ADJ
fnp-2920	101	38	in	in	ADP
fnp-2920	101	39	controls	control	NOUN
fnp-2920	101	40	,	,	PUNCT
fnp-2920	101	41	in	in	ADP
fnp-2920	101	42	both	both	PRON
fnp-2920	101	43	substantia	substantia	NOUN
fnp-2920	101	44	nigra	nigra	NOUN
fnp-2920	101	45	and	and	CCONJ
fnp-2920	101	46	colonic	colonic	NOUN
fnp-2920	101	47	biopsies	biopsy	NOUN
fnp-2920	101	48	(	(	PUNCT
fnp-2920	101	49	n=2	n=2	ADV
fnp-2920	101	50	)	)	PUNCT
fnp-2920	101	51	;	;	PUNCT
fnp-2920	101	52	pi	pi	NOUN
fnp-2920	101	53	values	value	NOUN
fnp-2920	101	54	and	and	CCONJ
fnp-2920	101	55	positions	position	NOUN
fnp-2920	101	56	of	of	ADP
fnp-2920	101	57	molecular	molecular	ADJ
fnp-2920	101	58	weight	weight	NOUN
fnp-2920	101	59	standards	standard	NOUN
fnp-2920	101	60	are	be	AUX
fnp-2920	101	61	indicated	indicate	VERB
fnp-2920	101	62	.	.	PUNCT
fnp-2920	102	1	an	an	DET
fnp-2920	102	2	equivalent	equivalent	ADJ
fnp-2920	102	3	amount	amount	NOUN
fnp-2920	102	4	of	of	ADP
fnp-2920	102	5	protein	protein	NOUN
fnp-2920	102	6	was	be	AUX
fnp-2920	102	7	loaded	load	VERB
fnp-2920	102	8	in	in	ADP
fnp-2920	102	9	a	a	DET
fnp-2920	102	10	-	-	PUNCT
fnp-2920	102	11	b	b	NOUN
fnp-2920	102	12	and	and	CCONJ
fnp-2920	102	13	c	c	NOUN
fnp-2920	102	14	-	-	SYM
fnp-2920	102	15	d	d	NOUN
fnp-2920	102	16	,	,	PUNCT
fnp-2920	102	17	respectively	respectively	ADV
fnp-2920	102	18	.	.	PUNCT
fnp-2920	103	1	it	it	PRON
fnp-2920	103	2	has	have	AUX
fnp-2920	103	3	also	also	ADV
fnp-2920	103	4	been	be	AUX
fnp-2920	103	5	shown	show	VERB
fnp-2920	103	6	that	that	SCONJ
fnp-2920	103	7	pathological	pathological	ADJ
fnp-2920	103	8	alpha	alpha	NOUN
fnp-2920	103	9	-	-	PUNCT
fnp-2920	103	10	synuclein	synuclein	NOUN
fnp-2920	103	11	obtained	obtain	VERB
fnp-2920	103	12	from	from	ADP
fnp-2920	103	13	pd	pd	PROPN
fnp-2920	103	14	brain	brain	NOUN
fnp-2920	103	15	has	have	VERB
fnp-2920	103	16	the	the	DET
fnp-2920	103	17	ability	ability	NOUN
fnp-2920	103	18	to	to	PART
fnp-2920	103	19	trigger	trigger	VERB
fnp-2920	103	20	alpha	alpha	NOUN
fnp-2920	103	21	-	-	PUNCT
fnp-2920	103	22	synuclein	synuclein	NOUN
fnp-2920	103	23	pathology	pathology	NOUN
fnp-2920	103	24	in	in	ADP
fnp-2920	103	25	the	the	DET
fnp-2920	103	26	cns	cns	NOUN
fnp-2920	103	27	of	of	ADP
fnp-2920	103	28	rodents	rodent	NOUN
fnp-2920	103	29	and	and	CCONJ
fnp-2920	103	30	non	non	ADJ
fnp-2920	103	31	-	-	ADJ
fnp-2920	103	32	human	human	ADJ
fnp-2920	103	33	primates	primate	NOUN
fnp-2920	103	34	[	[	X
fnp-2920	103	35	33	33	NUM
fnp-2920	103	36	,	,	PUNCT
fnp-2920	103	37	34	34	NUM
fnp-2920	103	38	]	]	PUNCT
fnp-2920	103	39	.	.	PUNCT
fnp-2920	104	1	for	for	ADP
fnp-2920	104	2	example	example	NOUN
fnp-2920	104	3	,	,	PUNCT
fnp-2920	104	4	the	the	DET
fnp-2920	104	5	intranigral	intranigral	ADJ
fnp-2920	104	6	inoculation	inoculation	NOUN
fnp-2920	104	7	of	of	ADP
fnp-2920	104	8	alpha	alpha	NOUN
fnp-2920	104	9	-	-	PUNCT
fnp-2920	104	10	synuclein	synuclein	NOUN
fnp-2920	104	11	-	-	PUNCT
fnp-2920	104	12	containing	contain	VERB
fnp-2920	104	13	lb	lb	PRON
fnp-2920	104	14	extracts	extract	NOUN
fnp-2920	104	15	obtained	obtain	VERB
fnp-2920	104	16	from	from	ADP
fnp-2920	104	17	pd	pd	PROPN
fnp-2920	104	18	brains	brain	NOUN
fnp-2920	104	19	leads	lead	VERB
fnp-2920	104	20	to	to	ADP
fnp-2920	104	21	widespread	widespread	ADJ
fnp-2920	104	22	alpha	alpha	NOUN
fnp-2920	104	23	-	-	PUNCT
fnp-2920	104	24	synuclein	synuclein	NOUN
fnp-2920	104	25	pathology	pathology	NOUN
fnp-2920	104	26	together	together	ADV
fnp-2920	104	27	with	with	ADP
fnp-2920	104	28	dopaminergic	dopaminergic	ADJ
fnp-2920	104	29	neurodegeneration	neurodegeneration	NOUN
fnp-2920	104	30	in	in	ADP
fnp-2920	104	31	mice	mouse	NOUN
fnp-2920	104	32	and	and	CCONJ
fnp-2920	104	33	monkeys	monkey	NOUN
fnp-2920	104	34	[	[	X
fnp-2920	104	35	35	35	NUM
fnp-2920	104	36	]	]	PUNCT
fnp-2920	104	37	.	.	PUNCT
fnp-2920	105	1	for	for	ADP
fnp-2920	105	2	the	the	DET
fnp-2920	105	3	sake	sake	NOUN
fnp-2920	105	4	of	of	ADP
fnp-2920	105	5	comparisons	comparison	NOUN
fnp-2920	105	6	between	between	ADP
fnp-2920	105	7	brain	brain	NOUN
fnp-2920	105	8	and	and	CCONJ
fnp-2920	105	9	enteric	enteric	ADJ
fnp-2920	105	10	alpha	alpha	NOUN
fnp-2920	105	11	-	-	PUNCT
fnp-2920	105	12	synuclein	synuclein	NOUN
fnp-2920	105	13	,	,	PUNCT
fnp-2920	105	14	it	it	PRON
fnp-2920	105	15	is	be	AUX
fnp-2920	105	16	important	important	ADJ
fnp-2920	105	17	to	to	PART
fnp-2920	105	18	know	know	VERB
fnp-2920	105	19	if	if	SCONJ
fnp-2920	105	20	pathological	pathological	ADJ
fnp-2920	105	21	alpha	alpha	NOUN
fnp-2920	105	22	-	-	PUNCT
fnp-2920	105	23	synuclein	synuclein	NOUN
fnp-2920	105	24	obtained	obtain	VERB
fnp-2920	105	25	from	from	ADP
fnp-2920	105	26	the	the	DET
fnp-2920	105	27	gi	gi	PROPN
fnp-2920	105	28	tract	tract	NOUN
fnp-2920	105	29	shares	share	NOUN
fnp-2920	105	30	the	the	DET
fnp-2920	105	31	same	same	ADJ
fnp-2920	105	32	pathogenic	pathogenic	ADJ
fnp-2920	105	33	capacity	capacity	NOUN
fnp-2920	105	34	.	.	PUNCT
fnp-2920	106	1	although	although	SCONJ
fnp-2920	106	2	the	the	DET
fnp-2920	106	3	precise	precise	ADJ
fnp-2920	106	4	answer	answer	NOUN
fnp-2920	106	5	to	to	ADP
fnp-2920	106	6	this	this	DET
fnp-2920	106	7	question	question	NOUN
fnp-2920	106	8	remains	remain	VERB
fnp-2920	106	9	unknown	unknown	ADJ
fnp-2920	106	10	,	,	PUNCT
fnp-2920	106	11	a	a	DET
fnp-2920	106	12	recent	recent	ADJ
fnp-2920	106	13	study	study	NOUN
fnp-2920	106	14	evaluated	evaluate	VERB
fnp-2920	106	15	the	the	DET
fnp-2920	106	16	effects	effect	NOUN
fnp-2920	106	17	of	of	ADP
fnp-2920	106	18	alpha	alpha	NOUN
fnp-2920	106	19	-	-	PUNCT
fnp-2920	106	20	synuclein	synuclein	NOUN
fnp-2920	106	21	aggregates	aggregate	NOUN
fnp-2920	106	22	from	from	ADP
fnp-2920	106	23	post	post	ADJ
fnp-2920	106	24	-	-	ADJ
fnp-2920	106	25	mortem	mortem	ADJ
fnp-2920	106	26	pd	pd	NOUN
fnp-2920	106	27	stellate	stellate	ADJ
fnp-2920	106	28	ganglia	ganglia	NOUN
fnp-2920	106	29	(	(	PUNCT
fnp-2920	106	30	pooled	pool	VERB
fnp-2920	106	31	from	from	ADP
fnp-2920	106	32	3	3	NUM
fnp-2920	106	33	patients	patient	NOUN
fnp-2920	106	34	)	)	PUNCT
fnp-2920	106	35	injected	inject	VERB
fnp-2920	106	36	into	into	ADP
fnp-2920	106	37	mouse	mouse	NOUN
fnp-2920	106	38	brain	brain	NOUN
fnp-2920	107	1	[	[	X
fnp-2920	107	2	36	36	NUM
fnp-2920	107	3	]	]	PUNCT
fnp-2920	107	4	.	.	PUNCT
fnp-2920	108	1	stellate	stellate	ADJ
fnp-2920	108	2	ganglion	ganglion	NOUN
fnp-2920	108	3	is	be	AUX
fnp-2920	108	4	a	a	DET
fnp-2920	108	5	paravertebral	paravertebral	ADJ
fnp-2920	108	6	ganglion	ganglion	NOUN
fnp-2920	108	7	,	,	PUNCT
fnp-2920	108	8	which	which	PRON
fnp-2920	108	9	like	like	ADP
fnp-2920	108	10	the	the	DET
fnp-2920	108	11	gut	gut	NOUN
fnp-2920	108	12	,	,	PUNCT
fnp-2920	108	13	exhibits	exhibit	VERB
fnp-2920	108	14	marked	mark	VERB
fnp-2920	108	15	lewy	lewy	PROPN
fnp-2920	108	16	pathology	pathology	NOUN
fnp-2920	108	17	in	in	ADP
fnp-2920	108	18	almost	almost	ADV
fnp-2920	108	19	all	all	PRON
fnp-2920	108	20	pd	pd	NOUN
fnp-2920	108	21	subjects	subject	NOUN
fnp-2920	108	22	[	[	X
fnp-2920	108	23	4	4	NUM
fnp-2920	108	24	,	,	PUNCT
fnp-2920	108	25	37	37	NUM
fnp-2920	108	26	]	]	PUNCT
fnp-2920	108	27	.	.	PUNCT
fnp-2920	109	1	in	in	ADP
fnp-2920	109	2	contrast	contrast	NOUN
fnp-2920	109	3	to	to	ADP
fnp-2920	109	4	the	the	DET
fnp-2920	109	5	findings	finding	NOUN
fnp-2920	109	6	obtained	obtain	VERB
fnp-2920	109	7	with	with	ADP
fnp-2920	109	8	substantia	substantia	NOUN
fnp-2920	109	9	nigra	nigra	NOUN
fnp-2920	109	10	-	-	PUNCT
fnp-2920	109	11	derived	derive	VERB
fnp-2920	109	12	alpha	alpha	NOUN
fnp-2920	109	13	-	-	PUNCT
fnp-2920	109	14	synuclein	synuclein	NOUN
fnp-2920	109	15	,	,	PUNCT
fnp-2920	109	16	no	no	DET
fnp-2920	109	17	pathological	pathological	ADJ
fnp-2920	109	18	effects	effect	NOUN
fnp-2920	109	19	were	be	AUX
fnp-2920	109	20	observed	observe	VERB
fnp-2920	109	21	when	when	SCONJ
fnp-2920	109	22	peripheral	peripheral	ADJ
fnp-2920	109	23	aggregates	aggregate	NOUN
fnp-2920	109	24	from	from	ADP
fnp-2920	109	25	stellate	stellate	ADJ
fnp-2920	109	26	ganglion	ganglion	NOUN
fnp-2920	109	27	were	be	AUX
fnp-2920	109	28	injected	inject	VERB
fnp-2920	109	29	into	into	ADP
fnp-2920	109	30	the	the	DET
fnp-2920	109	31	brain	brain	NOUN
fnp-2920	109	32	of	of	ADP
fnp-2920	109	33	wild	wild	ADJ
fnp-2920	109	34	-	-	PUNCT
fnp-2920	109	35	type	type	NOUN
fnp-2920	109	36	mice	mouse	NOUN
fnp-2920	109	37	,	,	PUNCT
fnp-2920	109	38	at	at	ADP
fnp-2920	109	39	least	least	ADJ
fnp-2920	109	40	up	up	ADP
fnp-2920	109	41	to	to	PART
fnp-2920	109	42	6	6	NUM
fnp-2920	109	43	months	month	NOUN
fnp-2920	109	44	following	follow	VERB
fnp-2920	109	45	injection	injection	NOUN
fnp-2920	109	46	[	[	X
fnp-2920	109	47	36	36	NUM
fnp-2920	109	48	]	]	PUNCT
fnp-2920	109	49	.	.	PUNCT
fnp-2920	110	1	this	this	DET
fnp-2920	110	2	intriguing	intriguing	ADJ
fnp-2920	110	3	observation	observation	NOUN
fnp-2920	110	4	,	,	PUNCT
fnp-2920	110	5	which	which	PRON
fnp-2920	110	6	casts	cast	VERB
fnp-2920	110	7	doubt	doubt	NOUN
fnp-2920	110	8	on	on	ADP
fnp-2920	110	9	the	the	DET
fnp-2920	110	10	pathogenicity	pathogenicity	NOUN
fnp-2920	110	11	of	of	ADP
fnp-2920	110	12	peripheral	peripheral	ADJ
fnp-2920	110	13	alpha	alpha	NOUN
fnp-2920	110	14	-	-	PUNCT
fnp-2920	110	15	synuclein	synuclein	NOUN
fnp-2920	110	16	,	,	PUNCT
fnp-2920	110	17	requires	require	VERB
fnp-2920	110	18	replication	replication	NOUN
fnp-2920	110	19	using	use	VERB
fnp-2920	110	20	extracts	extract	NOUN
fnp-2920	110	21	from	from	ADP
fnp-2920	110	22	other	other	ADJ
fnp-2920	110	23	peripheral	peripheral	ADJ
fnp-2920	110	24	organs	organ	NOUN
fnp-2920	110	25	affected	affect	VERB
fnp-2920	110	26	by	by	ADP
fnp-2920	110	27	lewy	lewy	PROPN
fnp-2920	110	28	pathology	pathology	PROPN
fnp-2920	110	29	,	,	PUNCT
fnp-2920	110	30	such	such	ADJ
fnp-2920	110	31	as	as	ADP
fnp-2920	110	32	the	the	DET
fnp-2920	110	33	gi	gi	PROPN
fnp-2920	110	34	tract	tract	NOUN
fnp-2920	110	35	or	or	CCONJ
fnp-2920	110	36	the	the	DET
fnp-2920	110	37	salivary	salivary	ADJ
fnp-2920	110	38	glands	gland	NOUN
fnp-2920	111	1	[	[	X
fnp-2920	111	2	3	3	NUM
fnp-2920	111	3	,	,	PUNCT
fnp-2920	111	4	38	38	NUM
fnp-2920	111	5	]	]	PUNCT
fnp-2920	111	6	.	.	PUNCT
fnp-2920	112	1	is	be	AUX
fnp-2920	112	2	there	there	PRON
fnp-2920	112	3	any	any	DET
fnp-2920	112	4	enteric	enteric	ADJ
fnp-2920	112	5	neuronal	neuronal	ADJ
fnp-2920	112	6	loss	loss	NOUN
fnp-2920	112	7	in	in	ADP
fnp-2920	112	8	pd	pd	PROPN
fnp-2920	112	9	?	?	PROPN
fnp-2920	113	1	in	in	ADP
fnp-2920	113	2	the	the	DET
fnp-2920	113	3	substantia	substantia	NOUN
fnp-2920	113	4	nigra	nigra	NOUN
fnp-2920	113	5	of	of	ADP
fnp-2920	113	6	pd	pd	PROPN
fnp-2920	113	7	subjects	subject	NOUN
fnp-2920	113	8	,	,	PUNCT
fnp-2920	113	9	the	the	DET
fnp-2920	113	10	presence	presence	NOUN
fnp-2920	113	11	of	of	ADP
fnp-2920	113	12	alpha	alpha	NOUN
fnp-2920	113	13	-	-	PUNCT
fnp-2920	113	14	synuclein	synuclein	NOUN
fnp-2920	113	15	aggregates	aggregate	NOUN
fnp-2920	113	16	is	be	AUX
fnp-2920	113	17	accompanied	accompany	VERB
fnp-2920	113	18	by	by	ADP
fnp-2920	113	19	severe	severe	ADJ
fnp-2920	113	20	neuronal	neuronal	ADJ
fnp-2920	113	21	loss	loss	NOUN
fnp-2920	113	22	and	and	CCONJ
fnp-2920	113	23	clinicopathological	clinicopathological	ADJ
fnp-2920	113	24	findings	finding	NOUN
fnp-2920	113	25	strongly	strongly	ADV
fnp-2920	113	26	suggest	suggest	VERB
fnp-2920	113	27	that	that	SCONJ
fnp-2920	113	28	the	the	DET
fnp-2920	113	29	classical	classical	ADJ
fnp-2920	113	30	pd	pd	NOUN
fnp-2920	113	31	motor	motor	NOUN
fnp-2920	113	32	symptoms	symptom	NOUN
fnp-2920	113	33	,	,	PUNCT
fnp-2920	113	34	including	include	VERB
fnp-2920	113	35	bradykinesia	bradykinesia	PROPN
fnp-2920	113	36	and	and	CCONJ
fnp-2920	113	37	hypertonia	hypertonia	PROPN
fnp-2920	113	38	,	,	PUNCT
fnp-2920	113	39	are	be	AUX
fnp-2920	113	40	driven	drive	VERB
fnp-2920	113	41	primarily	primarily	ADV
fnp-2920	113	42	by	by	ADP
fnp-2920	113	43	neuronal	neuronal	ADJ
fnp-2920	113	44	loss	loss	NOUN
fnp-2920	113	45	rather	rather	ADV
fnp-2920	113	46	than	than	ADP
fnp-2920	113	47	only	only	ADV
fnp-2920	113	48	the	the	DET
fnp-2920	113	49	aggregation	aggregation	NOUN
fnp-2920	113	50	of	of	ADP
fnp-2920	113	51	alpha	alpha	NOUN
fnp-2920	113	52	-	-	PUNCT
fnp-2920	113	53	synuclein	synuclein	NOUN
fnp-2920	113	54	[	[	X
fnp-2920	113	55	39	39	NUM
fnp-2920	113	56	]	]	PUNCT
fnp-2920	113	57	.	.	PUNCT
fnp-2920	114	1	as	as	ADP
fnp-2920	114	2	such	such	ADJ
fnp-2920	114	3	,	,	PUNCT
fnp-2920	114	4	the	the	DET
fnp-2920	114	5	quantitative	quantitative	ADJ
fnp-2920	114	6	evaluation	evaluation	NOUN
fnp-2920	114	7	of	of	ADP
fnp-2920	114	8	enteric	enteric	ADJ
fnp-2920	114	9	neuron	neuron	NOUN
fnp-2920	114	10	populations	population	NOUN
fnp-2920	114	11	is	be	AUX
fnp-2920	114	12	important	important	ADJ
fnp-2920	114	13	to	to	PART
fnp-2920	114	14	determine	determine	VERB
fnp-2920	114	15	the	the	DET
fnp-2920	114	16	pathological	pathological	ADJ
fnp-2920	114	17	underpinnings	underpinning	NOUN
fnp-2920	114	18	of	of	ADP
fnp-2920	114	19	gi	gi	NOUN
fnp-2920	114	20	symptoms	symptom	NOUN
fnp-2920	114	21	,	,	PUNCT
fnp-2920	114	22	which	which	PRON
fnp-2920	114	23	are	be	AUX
fnp-2920	114	24	so	so	ADV
fnp-2920	114	25	frequently	frequently	ADV
fnp-2920	114	26	observed	observe	VERB
fnp-2920	114	27	in	in	ADP
fnp-2920	114	28	pd	pd	PROPN
fnp-2920	114	29	[	[	X
fnp-2920	114	30	40	40	NUM
fnp-2920	114	31	]	]	PUNCT
fnp-2920	114	32	.	.	PUNCT
fnp-2920	115	1	with	with	SCONJ
fnp-2920	115	2	that	that	PRON
fnp-2920	115	3	said	say	VERB
fnp-2920	115	4	,	,	PUNCT
fnp-2920	115	5	and	and	CCONJ
fnp-2920	115	6	despite	despite	SCONJ
fnp-2920	115	7	the	the	DET
fnp-2920	115	8	publication	publication	NOUN
fnp-2920	115	9	of	of	ADP
fnp-2920	115	10	proposed	propose	VERB
fnp-2920	115	11	guidelines	guideline	NOUN
fnp-2920	115	12	and	and	CCONJ
fnp-2920	115	13	consensus	consensus	NOUN
fnp-2920	115	14	techniques	technique	NOUN
fnp-2920	115	15	,	,	PUNCT
fnp-2920	115	16	the	the	DET
fnp-2920	115	17	quantification	quantification	NOUN
fnp-2920	115	18	of	of	ADP
fnp-2920	115	19	submucosal	submucosal	NOUN
fnp-2920	115	20	and	and	CCONJ
fnp-2920	115	21	myenteric	myenteric	ADJ
fnp-2920	115	22	neuron	neuron	NOUN
fnp-2920	115	23	number	number	NOUN
fnp-2920	115	24	remains	remains	AUX
fnp-2920	115	25	challenging	challenge	VERB
fnp-2920	115	26	[	[	X
fnp-2920	115	27	41	41	NUM
fnp-2920	115	28	]	]	PUNCT
fnp-2920	115	29	,	,	PUNCT
fnp-2920	115	30	mainly	mainly	ADV
fnp-2920	115	31	because	because	SCONJ
fnp-2920	115	32	of	of	ADP
fnp-2920	115	33	the	the	DET
fnp-2920	115	34	fishnet	fishnet	NOUN
fnp-2920	115	35	-	-	PUNCT
fnp-2920	115	36	like	like	ADJ
fnp-2920	115	37	architecture	architecture	NOUN
fnp-2920	115	38	of	of	ADP
fnp-2920	115	39	the	the	DET
fnp-2920	115	40	ens	en	NOUN
fnp-2920	115	41	plexus	plexus	NOUN
fnp-2920	115	42	.	.	PUNCT
fnp-2920	116	1	in	in	ADP
fnp-2920	116	2	the	the	DET
fnp-2920	116	3	most	most	ADV
fnp-2920	116	4	comprehensive	comprehensive	ADJ
fnp-2920	116	5	post	post	ADJ
fnp-2920	116	6	-	-	ADJ
fnp-2920	116	7	mortem	mortem	ADJ
fnp-2920	116	8	study	study	NOUN
fnp-2920	116	9	to	to	ADP
fnp-2920	116	10	date	date	NOUN
fnp-2920	116	11	,	,	PUNCT
fnp-2920	116	12	annerino	annerino	PROPN
fnp-2920	116	13	et	et	PROPN
fnp-2920	116	14	al	al	PROPN
fnp-2920	116	15	.	.	PROPN
fnp-2920	116	16	used	use	VERB
fnp-2920	116	17	formalin	formalin	NOUN
fnp-2920	116	18	-	-	PUNCT
fnp-2920	116	19	fixed	fix	VERB
fnp-2920	116	20	paraffin	paraffin	NOUN
fnp-2920	116	21	embedded	embed	VERB
fnp-2920	116	22	sections	section	NOUN
fnp-2920	116	23	to	to	PART
fnp-2920	116	24	compare	compare	VERB
fnp-2920	116	25	myenteric	myenteric	ADJ
fnp-2920	116	26	neuron	neuron	NOUN
fnp-2920	116	27	density	density	NOUN
fnp-2920	116	28	along	along	ADP
fnp-2920	116	29	the	the	DET
fnp-2920	116	30	length	length	NOUN
fnp-2920	116	31	of	of	ADP
fnp-2920	116	32	the	the	DET
fnp-2920	116	33	gi	gi	NOUN
fnp-2920	116	34	tract	tract	NOUN
fnp-2920	116	35	in	in	ADP
fnp-2920	116	36	6	6	NUM
fnp-2920	116	37	patients	patient	NOUN
fnp-2920	116	38	with	with	ADP
fnp-2920	116	39	pd	pd	PROPN
fnp-2920	116	40	and	and	CCONJ
fnp-2920	116	41	12	12	NUM
fnp-2920	116	42	controls	control	NOUN
fnp-2920	116	43	.	.	PUNCT
fnp-2920	117	1	there	there	PRON
fnp-2920	117	2	were	be	VERB
fnp-2920	117	3	no	no	DET
fnp-2920	117	4	differences	difference	NOUN
fnp-2920	117	5	in	in	ADP
fnp-2920	117	6	total	total	ADJ
fnp-2920	117	7	myenteric	myenteric	ADJ
fnp-2920	117	8	neuron	neuron	NOUN
fnp-2920	117	9	density	density	NOUN
fnp-2920	117	10	between	between	ADP
fnp-2920	117	11	controls	control	NOUN
fnp-2920	117	12	or	or	CCONJ
fnp-2920	117	13	patients	patient	NOUN
fnp-2920	117	14	in	in	ADP
fnp-2920	117	15	any	any	DET
fnp-2920	117	16	segment	segment	NOUN
fnp-2920	117	17	examined	examine	VERB
fnp-2920	117	18	[	[	PUNCT
fnp-2920	117	19	42	42	NUM
fnp-2920	117	20	]	]	PUNCT
fnp-2920	117	21	.	.	PUNCT
fnp-2920	118	1	similarly	similarly	ADV
fnp-2920	118	2	,	,	PUNCT
fnp-2920	118	3	when	when	SCONJ
fnp-2920	118	4	whole	whole	ADJ
fnp-2920	118	5	mounts	mount	NOUN
fnp-2920	118	6	of	of	ADP
fnp-2920	118	7	submucosa	submucosa	PROPN
fnp-2920	118	8	obtained	obtain	VERB
fnp-2920	118	9	from	from	ADP
fnp-2920	118	10	colonic	colonic	ADJ
fnp-2920	118	11	biopsies	biopsy	NOUN
fnp-2920	118	12	were	be	AUX
fnp-2920	118	13	analysed	analyse	VERB
fnp-2920	118	14	by	by	ADP
fnp-2920	118	15	immunohistochemistry	immunohistochemistry	NOUN
fnp-2920	118	16	,	,	PUNCT
fnp-2920	118	17	no	no	DET
fnp-2920	118	18	major	major	ADJ
fnp-2920	118	19	decrease	decrease	NOUN
fnp-2920	118	20	in	in	ADP
fnp-2920	118	21	neuronal	neuronal	ADJ
fnp-2920	118	22	density	density	NOUN
fnp-2920	118	23	was	be	AUX
fnp-2920	118	24	observed	observe	VERB
fnp-2920	118	25	in	in	ADP
fnp-2920	118	26	pd	pd	PROPN
fnp-2920	118	27	relative	relative	ADJ
fnp-2920	118	28	to	to	ADP
fnp-2920	118	29	controls	control	NOUN
fnp-2920	118	30	in	in	ADP
fnp-2920	118	31	two	two	NUM
fnp-2920	118	32	independent	independent	ADJ
fnp-2920	118	33	studies	study	NOUN
fnp-2920	118	34	that	that	PRON
fnp-2920	118	35	included	include	VERB
fnp-2920	118	36	a	a	DET
fnp-2920	118	37	total	total	NOUN
fnp-2920	118	38	of	of	ADP
fnp-2920	118	39	58	58	NUM
fnp-2920	118	40	pd	pd	NOUN
fnp-2920	118	41	and	and	CCONJ
fnp-2920	118	42	30	30	NUM
fnp-2920	118	43	control	control	NOUN
fnp-2920	118	44	cases	case	NOUN
fnp-2920	118	45	[	[	X
fnp-2920	118	46	8	8	NUM
fnp-2920	118	47	,	,	PUNCT
fnp-2920	118	48	43	43	NUM
fnp-2920	118	49	]	]	PUNCT
fnp-2920	118	50	.	.	PUNCT
fnp-2920	119	1	on	on	ADP
fnp-2920	119	2	the	the	DET
fnp-2920	119	3	whole	whole	NOUN
fnp-2920	119	4	,	,	PUNCT
fnp-2920	119	5	these	these	DET
fnp-2920	119	6	data	datum	NOUN
fnp-2920	119	7	strongly	strongly	ADV
fnp-2920	119	8	suggest	suggest	VERB
fnp-2920	119	9	that	that	SCONJ
fnp-2920	119	10	enteric	enteric	ADJ
fnp-2920	119	11	neuron	neuron	NOUN
fnp-2920	119	12	loss	loss	NOUN
fnp-2920	119	13	is	be	AUX
fnp-2920	119	14	not	not	PART
fnp-2920	119	15	a	a	DET
fnp-2920	119	16	feature	feature	NOUN
fnp-2920	119	17	of	of	ADP
fnp-2920	119	18	pd	pd	PROPN
fnp-2920	119	19	.	.	PROPN
fnp-2920	119	20	besides	besides	SCONJ
fnp-2920	119	21	alpha	alpha	NOUN
fnp-2920	119	22	-	-	PUNCT
fnp-2920	119	23	synuclein	synuclein	NOUN
fnp-2920	119	24	,	,	PUNCT
fnp-2920	119	25	are	be	AUX
fnp-2920	119	26	other	other	ADJ
fnp-2920	119	27	aggregated	aggregate	VERB
fnp-2920	119	28	proteins	protein	NOUN
fnp-2920	119	29	found	find	VERB
fnp-2920	119	30	in	in	ADP
fnp-2920	119	31	the	the	DET
fnp-2920	119	32	ens	en	NOUN
fnp-2920	119	33	?	?	PUNCT
fnp-2920	120	1	the	the	DET
fnp-2920	120	2	observation	observation	NOUN
fnp-2920	120	3	that	that	SCONJ
fnp-2920	120	4	alpha	alpha	NOUN
fnp-2920	120	5	-	-	PUNCT
fnp-2920	120	6	synuclein	synuclein	NOUN
fnp-2920	120	7	deposits	deposit	NOUN
fnp-2920	120	8	are	be	AUX
fnp-2920	120	9	a	a	DET
fnp-2920	120	10	feature	feature	NOUN
fnp-2920	120	11	of	of	ADP
fnp-2920	120	12	pd	pd	PROPN
fnp-2920	120	13	gut	gut	PROPN
fnp-2920	120	14	logically	logically	ADV
fnp-2920	120	15	leads	lead	VERB
fnp-2920	120	16	to	to	ADP
fnp-2920	120	17	speculation	speculation	NOUN
fnp-2920	120	18	that	that	SCONJ
fnp-2920	120	19	such	such	DET
fnp-2920	120	20	a	a	DET
fnp-2920	120	21	phenomenon	phenomenon	NOUN
fnp-2920	120	22	might	might	AUX
fnp-2920	120	23	also	also	ADV
fnp-2920	120	24	occur	occur	VERB
fnp-2920	120	25	in	in	ADP
fnp-2920	120	26	other	other	ADJ
fnp-2920	120	27	neurodegenerative	neurodegenerative	ADJ
fnp-2920	120	28	disorders	disorder	NOUN
fnp-2920	120	29	such	such	ADJ
fnp-2920	120	30	as	as	ADP
fnp-2920	120	31	tauopathies	tauopathie	NOUN
fnp-2920	120	32	.	.	PUNCT
fnp-2920	121	1	like	like	ADP
fnp-2920	121	2	alpha	alpha	NOUN
fnp-2920	121	3	-	-	PUNCT
fnp-2920	121	4	synuclein	synuclein	NOUN
fnp-2920	121	5	,	,	PUNCT
fnp-2920	121	6	tau	tau	PROPN
fnp-2920	121	7	is	be	AUX
fnp-2920	121	8	physiologically	physiologically	ADV
fnp-2920	121	9	expressed	express	VERB
fnp-2920	121	10	by	by	ADP
fnp-2920	121	11	enteric	enteric	ADJ
fnp-2920	121	12	neurons	neuron	NOUN
fnp-2920	121	13	.	.	PUNCT
fnp-2920	122	1	however	however	ADV
fnp-2920	122	2	,	,	PUNCT
fnp-2920	122	3	in	in	ADP
fnp-2920	122	4	contrast	contrast	NOUN
fnp-2920	122	5	to	to	ADP
fnp-2920	122	6	the	the	DET
fnp-2920	122	7	cns	cns	PROPN
fnp-2920	122	8	neurons	neuron	NOUN
fnp-2920	122	9	that	that	PRON
fnp-2920	122	10	express	express	VERB
fnp-2920	122	11	all	all	DET
fnp-2920	122	12	six	six	NUM
fnp-2920	122	13	tau	tau	NOUN
fnp-2920	122	14	isoforms	isoform	NOUN
fnp-2920	122	15	,	,	PUNCT
fnp-2920	122	16	adult	adult	NOUN
fnp-2920	122	17	human	human	NOUN
fnp-2920	122	18	ens	ens	NOUN
fnp-2920	122	19	primarily	primarily	ADV
fnp-2920	122	20	express	express	VERB
fnp-2920	122	21	only	only	ADV
fnp-2920	122	22	two	two	NUM
fnp-2920	122	23	tau	tau	NOUN
fnp-2920	122	24	isoforms	isoform	VERB
fnp-2920	122	25	[	[	X
fnp-2920	122	26	44	44	NUM
fnp-2920	122	27	]	]	PUNCT
fnp-2920	122	28	.	.	PUNCT
fnp-2920	123	1	tau	tau	PROPN
fnp-2920	123	2	aggregates	aggregate	NOUN
fnp-2920	123	3	found	find	VERB
fnp-2920	123	4	in	in	ADP
fnp-2920	123	5	tauopathies	tauopathie	NOUN
fnp-2920	123	6	generally	generally	ADV
fnp-2920	123	7	contain	contain	VERB
fnp-2920	123	8	tau	tau	PROPN
fnp-2920	123	9	in	in	ADP
fnp-2920	123	10	an	an	DET
fnp-2920	123	11	elevated	elevated	ADJ
fnp-2920	123	12	state	state	NOUN
fnp-2920	123	13	of	of	ADP
fnp-2920	123	14	phosphorylation	phosphorylation	NOUN
fnp-2920	123	15	that	that	PRON
fnp-2920	123	16	is	be	AUX
fnp-2920	123	17	often	often	ADV
fnp-2920	123	18	aberrantly	aberrantly	ADV
fnp-2920	123	19	cleaved	cleave	VERB
fnp-2920	123	20	[	[	X
fnp-2920	123	21	45	45	NUM
fnp-2920	123	22	]	]	PUNCT
fnp-2920	123	23	.	.	PUNCT
fnp-2920	124	1	in	in	ADP
fnp-2920	124	2	a	a	DET
fnp-2920	124	3	preliminary	preliminary	ADJ
fnp-2920	124	4	report	report	NOUN
fnp-2920	124	5	,	,	PUNCT
fnp-2920	124	6	we	we	PRON
fnp-2920	124	7	analysed	analyse	VERB
fnp-2920	124	8	by	by	ADP
fnp-2920	124	9	western	western	ADJ
fnp-2920	124	10	blot	blot	NOUN
fnp-2920	124	11	colonic	colonic	NOUN
fnp-2920	124	12	biopsies	biopsy	NOUN
fnp-2920	124	13	from	from	ADP
fnp-2920	124	14	5	5	NUM
fnp-2920	124	15	patients	patient	NOUN
fnp-2920	124	16	with	with	ADP
fnp-2920	124	17	probable	probable	ADJ
fnp-2920	124	18	progressive	progressive	ADJ
fnp-2920	124	19	supranuclear	supranuclear	ADJ
fnp-2920	124	20	palsy	palsy	ADJ
fnp-2920	124	21	(	(	PUNCT
fnp-2920	124	22	psp	psp	NOUN
fnp-2920	124	23	)	)	PUNCT
fnp-2920	124	24	using	use	VERB
fnp-2920	124	25	2	2	NUM
fnp-2920	124	26	different	different	ADJ
fnp-2920	124	27	phospho	phospho	NOUN
fnp-2920	124	28	-	-	PUNCT
fnp-2920	124	29	tau	tau	NOUN
fnp-2920	124	30	antibodies	antibody	NOUN
fnp-2920	124	31	and	and	CCONJ
fnp-2920	124	32	one	one	NUM
fnp-2920	124	33	antibody	antibody	NOUN
fnp-2920	124	34	specific	specific	ADJ
fnp-2920	124	35	for	for	ADP
fnp-2920	124	36	caspase	caspase	NOUN
fnp-2920	124	37	-	-	PUNCT
fnp-2920	124	38	cleaved	cleave	VERB
fnp-2920	124	39	tau	tau	NOUN
fnp-2920	125	1	[	[	X
fnp-2920	125	2	44	44	NUM
fnp-2920	125	3	]	]	PUNCT
fnp-2920	125	4	.	.	PUNCT
fnp-2920	126	1	the	the	DET
fnp-2920	126	2	phosphorylation	phosphorylation	NOUN
fnp-2920	126	3	and	and	CCONJ
fnp-2920	126	4	truncation	truncation	NOUN
fnp-2920	126	5	patterns	pattern	NOUN
fnp-2920	126	6	of	of	ADP
fnp-2920	126	7	tau	tau	PROPN
fnp-2920	126	8	in	in	ADP
fnp-2920	126	9	psp	psp	NOUN
fnp-2920	126	10	were	be	AUX
fnp-2920	126	11	indistinguishable	indistinguishable	ADJ
fnp-2920	126	12	from	from	ADP
fnp-2920	126	13	those	those	PRON
fnp-2920	126	14	in	in	ADP
fnp-2920	126	15	controls	control	NOUN
fnp-2920	126	16	[	[	X
fnp-2920	126	17	44	44	NUM
fnp-2920	126	18	]	]	PUNCT
fnp-2920	126	19	.	.	PUNCT
fnp-2920	127	1	in	in	ADP
fnp-2920	127	2	a	a	DET
fnp-2920	127	3	subsequent	subsequent	ADJ
fnp-2920	127	4	study	study	NOUN
fnp-2920	127	5	,	,	PUNCT
fnp-2920	127	6	brittany	brittany	PROPN
fnp-2920	127	7	dugger	dugger	PROPN
fnp-2920	127	8	et	et	PROPN
fnp-2920	127	9	al	al	PROPN
fnp-2920	127	10	.	.	PROPN
fnp-2920	127	11	performed	perform	VERB
fnp-2920	127	12	a	a	DET
fnp-2920	127	13	comprehensive	comprehensive	ADJ
fnp-2920	127	14	immunohistochemical	immunohistochemical	ADJ
fnp-2920	127	15	analysis	analysis	NOUN
fnp-2920	127	16	of	of	ADP
fnp-2920	127	17	the	the	DET
fnp-2920	127	18	ens	ens	NOUN
fnp-2920	127	19	in	in	ADP
fnp-2920	127	20	tauopathies	tauopathie	NOUN
fnp-2920	127	21	.	.	PUNCT
fnp-2920	128	1	using	use	VERB
fnp-2920	128	2	formalin	formalin	NOUN
fnp-2920	128	3	fixed	fix	VERB
fnp-2920	128	4	paraffin	paraffin	NOUN
fnp-2920	128	5	embedded	embed	VERB
fnp-2920	128	6	sections	section	NOUN
fnp-2920	128	7	,	,	PUNCT
fnp-2920	128	8	they	they	PRON
fnp-2920	128	9	examined	examine	VERB
fnp-2920	128	10	the	the	DET
fnp-2920	128	11	sigmoid	sigmoid	NOUN
fnp-2920	128	12	colon	colon	NOUN
fnp-2920	128	13	in	in	ADP
fnp-2920	128	14	26	26	NUM
fnp-2920	128	15	psp	psp	NOUN
fnp-2920	128	16	,	,	PUNCT
fnp-2920	128	17	21	21	NUM
fnp-2920	128	18	ad	ad	NOUN
fnp-2920	128	19	and	and	CCONJ
fnp-2920	128	20	19	19	NUM
fnp-2920	128	21	controls	control	NOUN
fnp-2920	128	22	using	use	VERB
fnp-2920	128	23	one	one	NUM
fnp-2920	128	24	antibody	antibody	NOUN
fnp-2920	128	25	for	for	ADP
fnp-2920	128	26	total	total	ADJ
fnp-2920	128	27	tau	tau	PROPN
fnp-2920	128	28	and	and	CCONJ
fnp-2920	128	29	two	two	NUM
fnp-2920	128	30	phospho	phospho	ADJ
fnp-2920	128	31	-	-	PUNCT
fnp-2920	128	32	tau	tau	NOUN
fnp-2920	128	33	antibodies	antibodie	VERB
fnp-2920	128	34	[	[	X
fnp-2920	128	35	46	46	NUM
fnp-2920	128	36	]	]	PUNCT
fnp-2920	128	37	.	.	PUNCT
fnp-2920	129	1	no	no	DET
fnp-2920	129	2	differences	difference	NOUN
fnp-2920	129	3	in	in	ADP
fnp-2920	129	4	the	the	DET
fnp-2920	129	5	staining	stain	VERB
fnp-2920	129	6	pattern	pattern	NOUN
fnp-2920	129	7	were	be	AUX
fnp-2920	129	8	observed	observe	VERB
fnp-2920	129	9	between	between	ADP
fnp-2920	129	10	colonic	colonic	ADJ
fnp-2920	129	11	specimen	speciman	NOUN
fnp-2920	129	12	from	from	ADP
fnp-2920	129	13	tauopathy	tauopathy	ADJ
fnp-2920	129	14	patients	patient	NOUN
fnp-2920	129	15	and	and	CCONJ
fnp-2920	129	16	controls	control	VERB
fnp-2920	129	17	[	[	X
fnp-2920	129	18	46	46	NUM
fnp-2920	129	19	]	]	PUNCT
fnp-2920	129	20	.	.	PUNCT
fnp-2920	130	1	so	so	ADV
fnp-2920	130	2	,	,	PUNCT
fnp-2920	130	3	enteric	enteric	ADJ
fnp-2920	130	4	synucleinopathy	synucleinopathy	NOUN
fnp-2920	130	5	:	:	PUNCT
fnp-2920	130	6	myth	myth	NOUN
fnp-2920	130	7	or	or	CCONJ
fnp-2920	130	8	reality	reality	NOUN
fnp-2920	130	9	?	?	PUNCT
fnp-2920	131	1	even	even	ADV
fnp-2920	131	2	if	if	SCONJ
fnp-2920	131	3	they	they	PRON
fnp-2920	131	4	are	be	AUX
fnp-2920	131	5	still	still	ADV
fnp-2920	131	6	preliminary	preliminary	ADJ
fnp-2920	131	7	,	,	PUNCT
fnp-2920	131	8	recent	recent	ADJ
fnp-2920	131	9	findings	finding	NOUN
fnp-2920	131	10	and	and	CCONJ
fnp-2920	131	11	in	in	ADP
fnp-2920	131	12	particular	particular	ADJ
fnp-2920	131	13	the	the	DET
fnp-2920	131	14	ones	one	NOUN
fnp-2920	131	15	obtained	obtain	VERB
fnp-2920	131	16	with	with	ADP
fnp-2920	131	17	ultrasensitive	ultrasensitive	ADJ
fnp-2920	131	18	amplification	amplification	NOUN
fnp-2920	131	19	techniques	technique	NOUN
fnp-2920	131	20	such	such	ADJ
fnp-2920	131	21	as	as	ADP
fnp-2920	131	22	pmca	pmca	NOUN
fnp-2920	131	23	,	,	PUNCT
fnp-2920	131	24	convincingly	convincingly	ADV
fnp-2920	131	25	showed	show	VERB
fnp-2920	131	26	that	that	SCONJ
fnp-2920	131	27	alpha	alpha	NOUN
fnp-2920	131	28	-	-	PUNCT
fnp-2920	131	29	synuclein	synuclein	NOUN
fnp-2920	131	30	aggregates	aggregate	NOUN
fnp-2920	131	31	with	with	ADP
fnp-2920	131	32	seeding	seeding	NOUN
fnp-2920	131	33	capacity	capacity	NOUN
fnp-2920	131	34	are	be	AUX
fnp-2920	131	35	found	find	VERB
fnp-2920	131	36	in	in	ADP
fnp-2920	131	37	the	the	DET
fnp-2920	131	38	ens	ens	NOUN
fnp-2920	131	39	[	[	X
fnp-2920	131	40	30	30	NUM
fnp-2920	131	41	,	,	PUNCT
fnp-2920	131	42	32	32	NUM
fnp-2920	131	43	]	]	PUNCT
fnp-2920	131	44	.	.	PUNCT
fnp-2920	132	1	it	it	PRON
fnp-2920	132	2	therefore	therefore	ADV
fnp-2920	132	3	seems	seem	VERB
fnp-2920	132	4	justified	justified	ADJ
fnp-2920	132	5	to	to	PART
fnp-2920	132	6	use	use	VERB
fnp-2920	132	7	the	the	DET
fnp-2920	132	8	word	word	NOUN
fnp-2920	132	9	‘	'	PUNCT
fnp-2920	132	10	enteric	enteric	ADJ
fnp-2920	132	11	synucleinopathy	synucleinopathy	NOUN
fnp-2920	132	12	’	'	PUNCT
fnp-2920	132	13	.	.	PUNCT
fnp-2920	133	1	that	that	PRON
fnp-2920	133	2	said	say	VERB
fnp-2920	133	3	,	,	PUNCT
fnp-2920	133	4	some	some	DET
fnp-2920	133	5	outstanding	outstanding	ADJ
fnp-2920	133	6	questions	question	NOUN
fnp-2920	133	7	remain	remain	VERB
fnp-2920	133	8	:	:	PUNCT
fnp-2920	133	9	(	(	PUNCT
fnp-2920	133	10	i	i	NOUN
fnp-2920	133	11	)	)	PUNCT
fnp-2920	133	12	existing	exist	VERB
fnp-2920	133	13	findings	finding	NOUN
fnp-2920	133	14	suggest	suggest	VERB
fnp-2920	133	15	that	that	SCONJ
fnp-2920	133	16	enteric	enteric	ADJ
fnp-2920	133	17	neuron	neuron	NOUN
fnp-2920	133	18	loss	loss	NOUN
fnp-2920	133	19	is	be	AUX
fnp-2920	133	20	not	not	PART
fnp-2920	133	21	a	a	DET
fnp-2920	133	22	feature	feature	NOUN
fnp-2920	133	23	of	of	ADP
fnp-2920	133	24	pd	pd	NOUN
fnp-2920	133	25	but	but	CCONJ
fnp-2920	133	26	there	there	PRON
fnp-2920	133	27	could	could	AUX
fnp-2920	133	28	be	be	AUX
fnp-2920	133	29	more	more	ADV
fnp-2920	133	30	subtle	subtle	ADJ
fnp-2920	133	31	morphologic	morphologic	ADJ
fnp-2920	133	32	changes	change	NOUN
fnp-2920	133	33	[	[	X
fnp-2920	133	34	47	47	NUM
fnp-2920	133	35	]	]	PUNCT
fnp-2920	133	36	that	that	PRON
fnp-2920	133	37	could	could	AUX
fnp-2920	133	38	be	be	AUX
fnp-2920	133	39	evaluated	evaluate	VERB
fnp-2920	133	40	in	in	ADP
fnp-2920	133	41	the	the	DET
fnp-2920	133	42	future	future	NOUN
fnp-2920	133	43	using	use	VERB
fnp-2920	133	44	computer	computer	NOUN
fnp-2920	133	45	-	-	PUNCT
fnp-2920	133	46	assisted	assist	VERB
fnp-2920	133	47	analysis	analysis	NOUN
fnp-2920	133	48	of	of	ADP
fnp-2920	133	49	the	the	DET
fnp-2920	133	50	enteric	enteric	ADJ
fnp-2920	133	51	neurons	neuron	NOUN
fnp-2920	134	1	[	[	X
fnp-2920	134	2	48	48	NUM
fnp-2920	134	3	]	]	PUNCT
fnp-2920	134	4	(	(	PUNCT
fnp-2920	134	5	ii	ii	NOUN
fnp-2920	134	6	)	)	PUNCT
fnp-2920	134	7	a	a	DET
fnp-2920	134	8	comprehensive	comprehensive	ADJ
fnp-2920	134	9	inventory	inventory	NOUN
fnp-2920	134	10	of	of	ADP
fnp-2920	134	11	alpha	alpha	NOUN
fnp-2920	134	12	-	-	PUNCT
fnp-2920	134	13	synuclein	synuclein	NOUN
fnp-2920	134	14	forms	form	NOUN
fnp-2920	134	15	present	present	VERB
fnp-2920	134	16	the	the	DET
fnp-2920	134	17	ens	ens	NOUN
fnp-2920	134	18	from	from	ADP
fnp-2920	134	19	patients	patient	NOUN
fnp-2920	134	20	with	with	ADP
fnp-2920	134	21	pd	pd	PROPN
fnp-2920	134	22	still	still	ADV
fnp-2920	134	23	need	need	VERB
fnp-2920	134	24	to	to	PART
fnp-2920	134	25	be	be	AUX
fnp-2920	134	26	carried	carry	VERB
fnp-2920	134	27	out	out	ADP
fnp-2920	134	28	,	,	PUNCT
fnp-2920	134	29	as	as	SCONJ
fnp-2920	134	30	has	have	AUX
fnp-2920	134	31	already	already	ADV
fnp-2920	134	32	been	be	AUX
fnp-2920	134	33	performed	perform	VERB
fnp-2920	134	34	for	for	ADP
fnp-2920	134	35	the	the	DET
fnp-2920	134	36	cns	cns	NOUN
fnp-2920	135	1	[	[	X
fnp-2920	135	2	27	27	NUM
fnp-2920	135	3	]	]	SYM
fnp-2920	135	4	(	(	PUNCT
fnp-2920	135	5	iii	iii	X
fnp-2920	135	6	)	)	PUNCT
fnp-2920	135	7	the	the	DET
fnp-2920	135	8	results	result	NOUN
fnp-2920	135	9	obtained	obtain	VERB
fnp-2920	135	10	with	with	ADP
fnp-2920	135	11	pmca	pmca	NOUN
fnp-2920	135	12	need	need	VERB
fnp-2920	135	13	to	to	PART
fnp-2920	135	14	be	be	AUX
fnp-2920	135	15	independently	independently	ADV
fnp-2920	135	16	replicated	replicate	VERB
fnp-2920	135	17	and	and	CCONJ
fnp-2920	135	18	confirmed	confirm	VERB
fnp-2920	135	19	by	by	ADP
fnp-2920	135	20	others	other	NOUN
fnp-2920	135	21	amplification	amplification	NOUN
fnp-2920	135	22	techniques	technique	NOUN
fnp-2920	135	23	such	such	ADJ
fnp-2920	135	24	as	as	ADP
fnp-2920	135	25	rt	rt	NOUN
fnp-2920	135	26	-	-	PUNCT
fnp-2920	135	27	quic	quic	PROPN
fnp-2920	135	28	(	(	PUNCT
fnp-2920	135	29	real	real	ADJ
fnp-2920	135	30	-	-	PUNCT
fnp-2920	135	31	time	time	NOUN
fnp-2920	135	32	quaking	quake	VERB
fnp-2920	135	33	-	-	PUNCT
fnp-2920	135	34	induced	induce	VERB
fnp-2920	135	35	conversion	conversion	NOUN
fnp-2920	135	36	)	)	PUNCT
fnp-2920	136	1	[	[	X
fnp-2920	136	2	49	49	NUM
fnp-2920	136	3	]	]	PUNCT
fnp-2920	136	4	.	.	PUNCT
fnp-2920	137	1	in	in	ADP
fnp-2920	137	2	addition	addition	NOUN
fnp-2920	137	3	,	,	PUNCT
fnp-2920	137	4	it	it	PRON
fnp-2920	137	5	still	still	ADV
fnp-2920	137	6	remains	remain	VERB
fnp-2920	137	7	to	to	PART
fnp-2920	137	8	be	be	AUX
fnp-2920	137	9	determined	determine	VERB
fnp-2920	137	10	if	if	SCONJ
fnp-2920	137	11	pathological	pathological	ADJ
fnp-2920	137	12	alpha	alpha	NOUN
fnp-2920	137	13	-	-	PUNCT
fnp-2920	137	14	synuclein	synuclein	NOUN
fnp-2920	137	15	purified	purify	VERB
fnp-2920	137	16	from	from	ADP
fnp-2920	137	17	the	the	DET
fnp-2920	137	18	ens	ens	NOUN
fnp-2920	137	19	is	be	AUX
fnp-2920	137	20	capable	capable	ADJ
fnp-2920	137	21	of	of	ADP
fnp-2920	137	22	promoting	promote	VERB
fnp-2920	137	23	alpha	alpha	NOUN
fnp-2920	137	24	-	-	PUNCT
fnp-2920	137	25	synuclein	synuclein	NOUN
fnp-2920	137	26	pathology	pathology	NOUN
fnp-2920	137	27	when	when	SCONJ
fnp-2920	137	28	intracerebrally	intracerebrally	ADV
fnp-2920	137	29	inoculated	inoculate	VERB
fnp-2920	137	30	,	,	PUNCT
fnp-2920	137	31	as	as	SCONJ
fnp-2920	137	32	already	already	ADV
fnp-2920	137	33	demonstrated	demonstrate	VERB
fnp-2920	137	34	for	for	ADP
fnp-2920	137	35	cns	cns	NOUN
fnp-2920	137	36	-	-	PUNCT
fnp-2920	137	37	derived	derive	VERB
fnp-2920	137	38	alpha	alpha	NOUN
fnp-2920	137	39	-	-	PUNCT
fnp-2920	137	40	synuclein	synuclein	NOUN
fnp-2920	137	41	aggregates	aggregate	NOUN
fnp-2920	137	42	[	[	X
fnp-2920	137	43	50	50	NUM
fnp-2920	137	44	]	]	PUNCT
fnp-2920	137	45	.	.	PUNCT
fnp-2920	138	1	this	this	PRON
fnp-2920	138	2	is	be	AUX
fnp-2920	138	3	a	a	DET
fnp-2920	138	4	critical	critical	ADJ
fnp-2920	138	5	issue	issue	NOUN
fnp-2920	138	6	with	with	ADP
fnp-2920	138	7	regard	regard	NOUN
fnp-2920	138	8	to	to	ADP
fnp-2920	138	9	pd	pd	NOUN
fnp-2920	138	10	pathogenesis	pathogenesis	NOUN
fnp-2920	138	11	as	as	SCONJ
fnp-2920	138	12	it	it	PRON
fnp-2920	138	13	has	have	AUX
fnp-2920	138	14	been	be	AUX
fnp-2920	138	15	speculated	speculate	VERB
fnp-2920	138	16	that	that	SCONJ
fnp-2920	138	17	enteric	enteric	ADJ
fnp-2920	138	18	alpha	alpha	NOUN
fnp-2920	138	19	-	-	PUNCT
fnp-2920	138	20	synuclein	synuclein	NOUN
fnp-2920	138	21	aggregates	aggregate	NOUN
fnp-2920	138	22	may	may	AUX
fnp-2920	138	23	spread	spread	VERB
fnp-2920	138	24	to	to	ADP
fnp-2920	138	25	the	the	DET
fnp-2920	138	26	cns	cns	NOUN
fnp-2920	138	27	via	via	ADP
fnp-2920	138	28	the	the	DET
fnp-2920	138	29	vagal	vagal	ADJ
fnp-2920	138	30	connections	connection	NOUN
fnp-2920	138	31	.	.	PUNCT
fnp-2920	139	1	however	however	ADV
fnp-2920	139	2	,	,	PUNCT
fnp-2920	139	3	performing	perform	VERB
fnp-2920	139	4	such	such	ADJ
fnp-2920	139	5	experiments	experiment	NOUN
fnp-2920	139	6	,	,	PUNCT
fnp-2920	139	7	which	which	PRON
fnp-2920	139	8	require	require	VERB
fnp-2920	139	9	purification	purification	NOUN
fnp-2920	139	10	of	of	ADP
fnp-2920	139	11	lb	lb	ADV
fnp-2920	139	12	-	-	PUNCT
fnp-2920	139	13	containing	contain	VERB
fnp-2920	139	14	fractions	fraction	NOUN
fnp-2920	139	15	from	from	ADP
fnp-2920	139	16	the	the	DET
fnp-2920	139	17	gut	gut	NOUN
fnp-2920	139	18	,	,	PUNCT
fnp-2920	139	19	can	can	AUX
fnp-2920	139	20	be	be	AUX
fnp-2920	139	21	challenging	challenge	VERB
fnp-2920	139	22	due	due	ADJ
fnp-2920	139	23	to	to	ADP
fnp-2920	139	24	the	the	DET
fnp-2920	139	25	low	low	ADJ
fnp-2920	139	26	frequency	frequency	NOUN
fnp-2920	139	27	and	and	CCONJ
fnp-2920	139	28	density	density	NOUN
fnp-2920	139	29	of	of	ADP
fnp-2920	139	30	aggregated	aggregate	VERB
fnp-2920	139	31	alpha	alpha	NOUN
fnp-2920	139	32	-	-	PUNCT
fnp-2920	139	33	synuclein	synuclein	NOUN
fnp-2920	139	34	in	in	ADP
fnp-2920	139	35	the	the	DET
fnp-2920	139	36	ens	ens	NOUN
fnp-2920	140	1	[	[	X
fnp-2920	140	2	3	3	NUM
fnp-2920	140	3	,	,	PUNCT
fnp-2920	140	4	51	51	NUM
fnp-2920	140	5	]	]	PUNCT
fnp-2920	140	6	.	.	PUNCT
fnp-2920	141	1	on	on	ADP
fnp-2920	141	2	the	the	DET
fnp-2920	141	3	whole	whole	NOUN
fnp-2920	141	4	,	,	PUNCT
fnp-2920	141	5	current	current	ADJ
fnp-2920	141	6	knowledge	knowledge	NOUN
fnp-2920	141	7	strongly	strongly	ADV
fnp-2920	141	8	supports	support	VERB
fnp-2920	141	9	the	the	DET
fnp-2920	141	10	existence	existence	NOUN
fnp-2920	141	11	of	of	ADP
fnp-2920	141	12	enteric	enteric	ADJ
fnp-2920	141	13	synucleinopathy	synucleinopathy	NOUN
fnp-2920	141	14	and	and	CCONJ
fnp-2920	141	15	these	these	DET
fnp-2920	141	16	data	datum	NOUN
fnp-2920	141	17	encourage	encourage	VERB
fnp-2920	141	18	future	future	ADJ
fnp-2920	141	19	studies	study	NOUN
fnp-2920	141	20	aimed	aim	VERB
fnp-2920	141	21	at	at	ADP
fnp-2920	141	22	expanding	expand	VERB
fnp-2920	141	23	our	our	PRON
fnp-2920	141	24	knowledge	knowledge	NOUN
fnp-2920	141	25	of	of	ADP
fnp-2920	141	26	peripheral	peripheral	ADJ
fnp-2920	141	27	pathology	pathology	NOUN
fnp-2920	141	28	in	in	ADP
fnp-2920	141	29	neurodegenerative	neurodegenerative	ADJ
fnp-2920	141	30	disorders	disorder	NOUN
fnp-2920	141	31	to	to	PART
fnp-2920	141	32	gain	gain	VERB
fnp-2920	141	33	clues	clue	NOUN
fnp-2920	141	34	that	that	PRON
fnp-2920	141	35	enable	enable	VERB
fnp-2920	141	36	further	further	ADJ
fnp-2920	141	37	understanding	understanding	NOUN
fnp-2920	141	38	of	of	ADP
fnp-2920	141	39	the	the	DET
fnp-2920	141	40	differential	differential	ADJ
fnp-2920	141	41	pathogenesis	pathogenesis	NOUN
fnp-2920	141	42	of	of	ADP
fnp-2920	141	43	these	these	DET
fnp-2920	141	44	disorders	disorder	NOUN
fnp-2920	141	45	.	.	PUNCT
fnp-2920	142	1	references	reference	NOUN
fnp-2920	142	2	1	1	NUM
fnp-2920	142	3	.	.	PUNCT
fnp-2920	143	1	schemann	schemann	PROPN
fnp-2920	143	2	m	m	PROPN
fnp-2920	143	3	,	,	PUNCT
fnp-2920	143	4	frieling	friele	VERB
fnp-2920	143	5	t	t	PROPN
fnp-2920	143	6	,	,	PUNCT
fnp-2920	143	7	enck	enck	ADV
fnp-2920	143	8	p	p	X
fnp-2920	143	9	(	(	PUNCT
fnp-2920	143	10	2020	2020	NUM
fnp-2920	143	11	)	)	PUNCT
fnp-2920	143	12	to	to	PART
fnp-2920	143	13	learn	learn	VERB
fnp-2920	143	14	,	,	PUNCT
fnp-2920	143	15	to	to	PART
fnp-2920	143	16	remember	remember	VERB
fnp-2920	143	17	,	,	PUNCT
fnp-2920	143	18	to	to	PART
fnp-2920	143	19	forget	forget	VERB
fnp-2920	143	20	-	-	PUNCT
fnp-2920	143	21	how	how	SCONJ
fnp-2920	143	22	smart	smart	ADJ
fnp-2920	143	23	is	be	AUX
fnp-2920	143	24	the	the	DET
fnp-2920	143	25	gut	gut	NOUN
fnp-2920	143	26	?	?	PUNCT
fnp-2920	144	1	acta	acta	PROPN
fnp-2920	144	2	physiol	physiol	PROPN
fnp-2920	144	3	(	(	PUNCT
fnp-2920	144	4	oxf	oxf	PROPN
fnp-2920	144	5	)	)	PUNCT
fnp-2920	144	6	228	228	NUM
fnp-2920	144	7	:	:	PUNCT
fnp-2920	144	8	e13296	e13296	NOUN
fnp-2920	144	9	.	.	NOUN
fnp-2920	144	10	https://doi.org/10.1111/apha.13296	https://doi.org/10.1111/apha.13296	NOUN
fnp-2920	144	11	2	2	X
fnp-2920	144	12	.	.	PUNCT
fnp-2920	145	1	goedert	goedert	PROPN
fnp-2920	145	2	m	m	PROPN
fnp-2920	145	3	,	,	PUNCT
fnp-2920	145	4	spillantini	spillantini	PROPN
fnp-2920	145	5	mg	mg	PROPN
fnp-2920	145	6	(	(	PUNCT
fnp-2920	145	7	1998	1998	NUM
fnp-2920	145	8	)	)	PUNCT
fnp-2920	145	9	lewy	lewy	PROPN
fnp-2920	145	10	body	body	NOUN
fnp-2920	145	11	diseases	disease	NOUN
fnp-2920	145	12	and	and	CCONJ
fnp-2920	145	13	multiple	multiple	ADJ
fnp-2920	145	14	system	system	NOUN
fnp-2920	145	15	atrophy	atrophy	NOUN
fnp-2920	145	16	as	as	ADP
fnp-2920	145	17	alpha	alpha	NOUN
fnp-2920	145	18	-	-	PUNCT
fnp-2920	145	19	synucleinopathies	synucleinopathie	NOUN
fnp-2920	145	20	.	.	PUNCT
fnp-2920	146	1	mol	mol	ADP
fnp-2920	146	2	psychiatry	psychiatry	NOUN
fnp-2920	146	3	3:462–465	3:462–465	PROPN
fnp-2920	146	4	.	.	PUNCT
fnp-2920	147	1	https://doi.org/10.1038/sj.mp.4000458	https://doi.org/10.1038/sj.mp.4000458	PROPN
fnp-2920	147	2	3	3	NUM
fnp-2920	147	3	.	.	PUNCT
fnp-2920	147	4	beach	beach	PROPN
fnp-2920	147	5	tg	tg	PROPN
fnp-2920	147	6	,	,	PUNCT
fnp-2920	147	7	adler	adler	PROPN
fnp-2920	147	8	ch	ch	PROPN
fnp-2920	147	9	,	,	PUNCT
fnp-2920	147	10	sue	sue	PROPN
fnp-2920	147	11	li	li	PROPN
fnp-2920	147	12	,	,	PUNCT
fnp-2920	147	13	et	et	PROPN
fnp-2920	147	14	al	al	PROPN
fnp-2920	147	15	(	(	PUNCT
fnp-2920	147	16	2010	2010	NUM
fnp-2920	147	17	)	)	PUNCT
fnp-2920	147	18	multi	multi	ADJ
fnp-2920	147	19	-	-	ADJ
fnp-2920	147	20	organ	organ	ADJ
fnp-2920	147	21	distribution	distribution	NOUN
fnp-2920	147	22	of	of	ADP
fnp-2920	147	23	phosphorylated	phosphorylate	VERB
fnp-2920	147	24	alpha	alpha	NOUN
fnp-2920	147	25	-	-	PUNCT
fnp-2920	147	26	synuclein	synuclein	NOUN
fnp-2920	147	27	histopathology	histopathology	NOUN
fnp-2920	147	28	in	in	ADP
fnp-2920	147	29	subjects	subject	NOUN
fnp-2920	147	30	with	with	ADP
fnp-2920	147	31	lewy	lewy	ADJ
fnp-2920	147	32	body	body	NOUN
fnp-2920	147	33	disorders	disorder	NOUN
fnp-2920	147	34	.	.	PUNCT
fnp-2920	148	1	acta	acta	PROPN
fnp-2920	148	2	neuropathol	neuropathol	PROPN
fnp-2920	148	3	119:689–702	119:689–702	PROPN
fnp-2920	148	4	.	.	PUNCT
fnp-2920	149	1	https://doi.org/10.1007/s00401-010-0664-3	https://doi.org/10.1007/s00401-010-0664-3	NUM
fnp-2920	150	1	4	4	NUM
fnp-2920	150	2	.	.	X
fnp-2920	150	3	gelpi	gelpi	NOUN
fnp-2920	150	4	e	e	NOUN
fnp-2920	150	5	,	,	PUNCT
fnp-2920	150	6	navarro	navarro	PROPN
fnp-2920	150	7	-	-	PUNCT
fnp-2920	150	8	otano	otano	PROPN
fnp-2920	150	9	j	j	PROPN
fnp-2920	150	10	,	,	PUNCT
fnp-2920	150	11	tolosa	tolosa	NOUN
fnp-2920	150	12	e	e	NOUN
fnp-2920	150	13	,	,	PUNCT
fnp-2920	150	14	et	et	PROPN
fnp-2920	150	15	al	al	PROPN
fnp-2920	150	16	(	(	PUNCT
fnp-2920	150	17	2014	2014	NUM
fnp-2920	150	18	)	)	PUNCT
fnp-2920	150	19	multiple	multiple	ADJ
fnp-2920	150	20	organ	organ	NOUN
fnp-2920	150	21	involvement	involvement	NOUN
fnp-2920	150	22	by	by	ADP
fnp-2920	150	23	alpha	alpha	NOUN
fnp-2920	150	24	-	-	PUNCT
fnp-2920	150	25	synuclein	synuclein	NOUN
fnp-2920	150	26	pathology	pathology	NOUN
fnp-2920	150	27	in	in	ADP
fnp-2920	150	28	lewy	lewy	PROPN
fnp-2920	150	29	body	body	NOUN
fnp-2920	150	30	disorders	disorder	NOUN
fnp-2920	150	31	.	.	PUNCT
fnp-2920	151	1	mov	mov	NOUN
fnp-2920	151	2	disord	disord	NOUN
fnp-2920	151	3	29:1010–1018	29:1010–1018	PROPN
fnp-2920	151	4	.	.	PUNCT
fnp-2920	152	1	https://doi.org/10.1002/mds.25776	https://doi.org/10.1002/mds.25776	PROPN
fnp-2920	152	2	5	5	NUM
fnp-2920	152	3	.	.	PUNCT
fnp-2920	152	4	punsoni	punsoni	PROPN
fnp-2920	152	5	m	m	PROPN
fnp-2920	152	6	,	,	PUNCT
fnp-2920	152	7	friedman	friedman	PROPN
fnp-2920	152	8	jh	jh	PROPN
fnp-2920	152	9	,	,	PUNCT
fnp-2920	152	10	resnick	resnick	PROPN
fnp-2920	152	11	m	m	PROPN
fnp-2920	152	12	,	,	PUNCT
fnp-2920	152	13	et	et	PROPN
fnp-2920	152	14	al	al	PROPN
fnp-2920	152	15	(	(	PUNCT
fnp-2920	152	16	2019	2019	NUM
fnp-2920	152	17	)	)	PUNCT
fnp-2920	152	18	enteric	enteric	ADJ
fnp-2920	152	19	pathologic	pathologic	ADJ
fnp-2920	152	20	manifestations	manifestation	NOUN
fnp-2920	152	21	of	of	ADP
fnp-2920	152	22	alpha	alpha	NOUN
fnp-2920	152	23	-	-	PUNCT
fnp-2920	152	24	synucleinopathies	synucleinopathie	NOUN
fnp-2920	152	25	.	.	PUNCT
fnp-2920	153	1	appl	appl	PROPN
fnp-2920	153	2	immunohistochem	immunohistochem	PROPN
fnp-2920	153	3	mol	mol	ADP
fnp-2920	153	4	morphol	morphol	PROPN
fnp-2920	153	5	27:543–548	27:543–548	NUM
fnp-2920	153	6	.	.	PUNCT
fnp-2920	154	1	https://doi.org/10.1097/pai.0000000000000613	https://doi.org/10.1097/pai.0000000000000613	PROPN
fnp-2920	154	2	6	6	NUM
fnp-2920	154	3	.	.	PUNCT
fnp-2920	155	1	aldecoa	aldecoa	PROPN
fnp-2920	155	2	i	i	PRON
fnp-2920	155	3	,	,	PUNCT
fnp-2920	155	4	navarro	navarro	PROPN
fnp-2920	155	5	-	-	PUNCT
fnp-2920	155	6	otano	otano	PROPN
fnp-2920	155	7	j	j	PROPN
fnp-2920	155	8	,	,	PUNCT
fnp-2920	155	9	stefanova	stefanova	PROPN
fnp-2920	155	10	n	n	CCONJ
fnp-2920	155	11	,	,	PUNCT
fnp-2920	155	12	et	et	PROPN
fnp-2920	155	13	al	al	PROPN
fnp-2920	155	14	(	(	PUNCT
fnp-2920	155	15	2015	2015	NUM
fnp-2920	155	16	)	)	PUNCT
fnp-2920	155	17	alpha	alpha	NOUN
fnp-2920	155	18	-	-	PUNCT
fnp-2920	155	19	synuclein	synuclein	NOUN
fnp-2920	155	20	immunoreactivity	immunoreactivity	NOUN
fnp-2920	155	21	patterns	pattern	NOUN
fnp-2920	155	22	in	in	ADP
fnp-2920	155	23	the	the	DET
fnp-2920	155	24	enteric	enteric	ADJ
fnp-2920	155	25	nervous	nervous	ADJ
fnp-2920	155	26	system	system	NOUN
fnp-2920	155	27	.	.	PUNCT
fnp-2920	156	1	neurosci	neurosci	PROPN
fnp-2920	156	2	lett	lett	PROPN
fnp-2920	156	3	602:145–149	602:145–149	NUM
fnp-2920	156	4	.	.	PUNCT
fnp-2920	157	1	https://doi.org/10.1016/j.neulet.2015.07.005	https://doi.org/10.1016/j.neulet.2015.07.005	VERB
fnp-2920	157	2	7	7	NUM
fnp-2920	157	3	.	.	PUNCT
fnp-2920	157	4	stokholm	stokholm	PROPN
fnp-2920	157	5	mg	mg	PROPN
fnp-2920	157	6	,	,	PUNCT
fnp-2920	157	7	danielsen	danielsen	VERB
fnp-2920	157	8	eh	eh	INTJ
fnp-2920	157	9	,	,	PUNCT
fnp-2920	157	10	hamilton	hamilton	PROPN
fnp-2920	157	11	-	-	PUNCT
fnp-2920	157	12	dutoit	dutoit	PROPN
fnp-2920	157	13	sj	sj	PROPN
fnp-2920	157	14	,	,	PUNCT
fnp-2920	157	15	borghammer	borghammer	NOUN
fnp-2920	157	16	p	p	PROPN
fnp-2920	157	17	(	(	PUNCT
fnp-2920	157	18	2016	2016	NUM
fnp-2920	157	19	)	)	PUNCT
fnp-2920	157	20	pathological	pathological	ADJ
fnp-2920	157	21	α	α	NOUN
fnp-2920	157	22	-	-	PUNCT
fnp-2920	157	23	synuclein	synuclein	NOUN
fnp-2920	157	24	in	in	ADP
fnp-2920	157	25	gastrointestinal	gastrointestinal	ADJ
fnp-2920	157	26	tissues	tissue	NOUN
fnp-2920	157	27	from	from	ADP
fnp-2920	157	28	prodromal	prodromal	ADJ
fnp-2920	157	29	parkinson	parkinson	NOUN
fnp-2920	157	30	disease	disease	NOUN
fnp-2920	157	31	patients	patient	NOUN
fnp-2920	157	32	.	.	PUNCT
fnp-2920	158	1	ann	ann	PROPN
fnp-2920	158	2	neurol	neurol	PROPN
fnp-2920	158	3	79:940–949	79:940–949	PROPN
fnp-2920	158	4	.	.	PUNCT
fnp-2920	159	1	https://doi.org/10.1002/ana.24648	https://doi.org/10.1002/ana.24648	PROPN
fnp-2920	159	2	8	8	NUM
fnp-2920	159	3	.	.	PUNCT
fnp-2920	159	4	lebouvier	lebouvier	PROPN
fnp-2920	159	5	t	t	PROPN
fnp-2920	159	6	,	,	PUNCT
fnp-2920	159	7	neunlist	neunlist	PROPN
fnp-2920	159	8	m	m	PROPN
fnp-2920	159	9	,	,	PUNCT
fnp-2920	159	10	bruley	bruley	PROPN
fnp-2920	159	11	des	des	PROPN
fnp-2920	159	12	varannes	varannes	PROPN
fnp-2920	159	13	s	s	PART
fnp-2920	159	14	,	,	PUNCT
fnp-2920	159	15	et	et	PROPN
fnp-2920	159	16	al	al	PROPN
fnp-2920	159	17	(	(	PUNCT
fnp-2920	159	18	2010	2010	NUM
fnp-2920	159	19	)	)	PUNCT
fnp-2920	159	20	colonic	colonic	NOUN
fnp-2920	159	21	biopsies	biopsy	NOUN
fnp-2920	159	22	to	to	PART
fnp-2920	159	23	assess	assess	VERB
fnp-2920	159	24	the	the	DET
fnp-2920	159	25	neuropathology	neuropathology	NOUN
fnp-2920	159	26	of	of	ADP
fnp-2920	159	27	parkinson	parkinson	NOUN
fnp-2920	159	28	’s	’s	PART
fnp-2920	159	29	disease	disease	NOUN
fnp-2920	159	30	and	and	CCONJ
fnp-2920	159	31	its	its	PRON
fnp-2920	159	32	relationship	relationship	NOUN
fnp-2920	159	33	with	with	ADP
fnp-2920	159	34	symptoms	symptom	NOUN
fnp-2920	159	35	.	.	PUNCT
fnp-2920	160	1	plos	plos	PROPN
fnp-2920	160	2	one	one	NUM
fnp-2920	160	3	5	5	NUM
fnp-2920	160	4	:	:	PUNCT
fnp-2920	160	5	e12728	e12728	NOUN
fnp-2920	160	6	.	.	PUNCT
fnp-2920	161	1	https://doi.org/10.1371/journal.pone.0012728	https://doi.org/10.1371/journal.pone.0012728	NOUN
fnp-2920	161	2	9	9	NUM
fnp-2920	161	3	.	.	PUNCT
fnp-2920	162	1	braak	braak	PROPN
fnp-2920	162	2	h	h	PROPN
fnp-2920	162	3	,	,	PUNCT
fnp-2920	162	4	de	de	PROPN
fnp-2920	162	5	vos	vos	PROPN
fnp-2920	162	6	rai	rai	PROPN
fnp-2920	162	7	,	,	PUNCT
fnp-2920	162	8	bohl	bohl	PROPN
fnp-2920	162	9	j	j	PROPN
fnp-2920	162	10	,	,	PUNCT
fnp-2920	162	11	del	del	PROPN
fnp-2920	162	12	tredici	tredici	PROPN
fnp-2920	162	13	k	k	PROPN
fnp-2920	162	14	(	(	PUNCT
fnp-2920	162	15	2006	2006	NUM
fnp-2920	162	16	)	)	PUNCT
fnp-2920	162	17	gastric	gastric	ADJ
fnp-2920	162	18	alpha	alpha	NOUN
fnp-2920	162	19	-	-	PUNCT
fnp-2920	162	20	synuclein	synuclein	NOUN
fnp-2920	162	21	immunoreactive	immunoreactive	ADJ
fnp-2920	162	22	inclusions	inclusion	NOUN
fnp-2920	162	23	in	in	ADP
fnp-2920	162	24	meissner	meissner	PROPN
fnp-2920	162	25	’s	’s	PART
fnp-2920	162	26	and	and	CCONJ
fnp-2920	162	27	auerbach	auerbach	VERB
fnp-2920	162	28	’s	’s	PART
fnp-2920	162	29	plexuses	plexus	NOUN
fnp-2920	162	30	in	in	ADP
fnp-2920	162	31	cases	case	NOUN
fnp-2920	162	32	staged	stage	VERB
fnp-2920	162	33	for	for	ADP
fnp-2920	162	34	parkinson	parkinson	NOUN
fnp-2920	162	35	’s	’s	PART
fnp-2920	162	36	disease	disease	NOUN
fnp-2920	162	37	-	-	PUNCT
fnp-2920	162	38	related	relate	VERB
fnp-2920	162	39	brain	brain	NOUN
fnp-2920	162	40	pathology	pathology	NOUN
fnp-2920	162	41	.	.	PUNCT
fnp-2920	163	1	neurosci	neurosci	PROPN
fnp-2920	163	2	lett	lett	PROPN
fnp-2920	163	3	396:67–72	396:67–72	NUM
fnp-2920	163	4	.	.	PUNCT
fnp-2920	164	1	https://doi.org/10.1016/j.neulet.2005.11.012	https://doi.org/10.1016/j.neulet.2005.11.012	NOUN
fnp-2920	164	2	10	10	NUM
fnp-2920	164	3	.	.	PUNCT
fnp-2920	165	1	qualman	qualman	NOUN
fnp-2920	165	2	sj	sj	PROPN
fnp-2920	165	3	,	,	PUNCT
fnp-2920	165	4	haupt	haupt	PROPN
fnp-2920	165	5	hm	hm	PROPN
fnp-2920	165	6	,	,	PUNCT
fnp-2920	165	7	yang	yang	PROPN
fnp-2920	165	8	p	p	PROPN
fnp-2920	165	9	,	,	PUNCT
fnp-2920	165	10	hamilton	hamilton	PROPN
fnp-2920	165	11	sr	sr	PROPN
fnp-2920	165	12	(	(	PUNCT
fnp-2920	165	13	1984	1984	NUM
fnp-2920	165	14	)	)	PUNCT
fnp-2920	165	15	esophageal	esophageal	NOUN
fnp-2920	165	16	lewy	lewy	ADJ
fnp-2920	165	17	bodies	body	NOUN
fnp-2920	165	18	associated	associate	VERB
fnp-2920	165	19	with	with	ADP
fnp-2920	165	20	ganglion	ganglion	NOUN
fnp-2920	165	21	cell	cell	NOUN
fnp-2920	165	22	loss	loss	NOUN
fnp-2920	165	23	in	in	ADP
fnp-2920	165	24	achalasia	achalasia	PROPN
fnp-2920	165	25	.	.	PUNCT
fnp-2920	166	1	similarity	similarity	NOUN
fnp-2920	166	2	to	to	AUX
fnp-2920	166	3	parkinson	parkinson	NOUN
fnp-2920	166	4	’s	’s	PART
fnp-2920	166	5	disease	disease	NOUN
fnp-2920	166	6	.	.	PUNCT
fnp-2920	167	1	gastroenterology	gastroenterology	NOUN
fnp-2920	167	2	87:848–856	87:848–856	PROPN
fnp-2920	167	3	.	.	PUNCT
fnp-2920	168	1	https://doi.org/10.1016/0016-5085(84)90079-9	https://doi.org/10.1016/0016-5085(84)90079-9	PROPN
fnp-2920	168	2	11	11	NUM
fnp-2920	168	3	.	.	PUNCT
fnp-2920	168	4	wakabayashi	wakabayashi	PROPN
fnp-2920	169	1	k	k	PROPN
fnp-2920	169	2	,	,	PUNCT
fnp-2920	169	3	takahashi	takahashi	PROPN
fnp-2920	169	4	h	h	PROPN
fnp-2920	169	5	,	,	PUNCT
fnp-2920	169	6	takeda	takeda	PROPN
fnp-2920	169	7	s	s	PART
fnp-2920	169	8	,	,	PUNCT
fnp-2920	169	9	et	et	PROPN
fnp-2920	169	10	al	al	PROPN
fnp-2920	169	11	(	(	PUNCT
fnp-2920	169	12	1988	1988	NUM
fnp-2920	169	13	)	)	PUNCT
fnp-2920	169	14	parkinson	parkinson	NOUN
fnp-2920	169	15	’s	’s	PART
fnp-2920	169	16	disease	disease	NOUN
fnp-2920	169	17	:	:	PUNCT
fnp-2920	169	18	the	the	DET
fnp-2920	169	19	presence	presence	NOUN
fnp-2920	169	20	of	of	ADP
fnp-2920	169	21	lewy	lewy	PROPN
fnp-2920	169	22	bodies	body	NOUN
fnp-2920	169	23	in	in	ADP
fnp-2920	169	24	auerbach	auerbach	PROPN
fnp-2920	169	25	’s	’s	PART
fnp-2920	169	26	and	and	CCONJ
fnp-2920	169	27	meissner	meissner	PROPN
fnp-2920	169	28	’s	’s	PART
fnp-2920	169	29	plexuses	plexus	NOUN
fnp-2920	169	30	.	.	PUNCT
fnp-2920	170	1	acta	acta	PROPN
fnp-2920	170	2	neuropathol	neuropathol	PROPN
fnp-2920	170	3	76:217–221	76:217–221	PROPN
fnp-2920	170	4	.	.	PUNCT
fnp-2920	171	1	https://doi.org/10.1007/bf00687767	https://doi.org/10.1007/bf00687767	NOUN
fnp-2920	171	2	12	12	NUM
fnp-2920	171	3	.	.	PUNCT
fnp-2920	172	1	maroteaux	maroteaux	PROPN
fnp-2920	172	2	l	l	PROPN
fnp-2920	172	3	,	,	PUNCT
fnp-2920	172	4	campanelli	campanelli	PROPN
fnp-2920	172	5	jt	jt	PROPN
fnp-2920	172	6	,	,	PUNCT
fnp-2920	172	7	scheller	scheller	PROPN
fnp-2920	172	8	rh	rh	PROPN
fnp-2920	172	9	(	(	PUNCT
fnp-2920	172	10	1988	1988	NUM
fnp-2920	172	11	)	)	PUNCT
fnp-2920	172	12	synuclein	synuclein	NOUN
fnp-2920	172	13	:	:	PUNCT
fnp-2920	172	14	a	a	DET
fnp-2920	172	15	neuron	neuron	NOUN
fnp-2920	172	16	-	-	PUNCT
fnp-2920	172	17	specific	specific	ADJ
fnp-2920	172	18	protein	protein	NOUN
fnp-2920	172	19	localized	localize	VERB
fnp-2920	172	20	to	to	ADP
fnp-2920	172	21	the	the	DET
fnp-2920	172	22	nucleus	nucleus	NOUN
fnp-2920	172	23	and	and	CCONJ
fnp-2920	172	24	presynaptic	presynaptic	ADJ
fnp-2920	172	25	nerve	nerve	NOUN
fnp-2920	172	26	terminal	terminal	NOUN
fnp-2920	172	27	.	.	PUNCT
fnp-2920	173	1	j	j	PROPN
fnp-2920	173	2	neurosci	neurosci	PROPN
fnp-2920	173	3	8:2804–2815	8:2804–2815	PROPN
fnp-2920	173	4	.	.	PUNCT
fnp-2920	174	1	https://doi.org/10.1523/jneurosci.08-08-02804.1988	https://doi.org/10.1523/jneurosci.08-08-02804.1988	ADJ
fnp-2920	174	2	13	13	NUM
fnp-2920	174	3	.	.	PUNCT
fnp-2920	175	1	burré	burré	PROPN
fnp-2920	175	2	j	j	PROPN
fnp-2920	175	3	,	,	PUNCT
fnp-2920	175	4	sharma	sharma	PROPN
fnp-2920	175	5	m	m	PROPN
fnp-2920	175	6	,	,	PUNCT
fnp-2920	175	7	südhof	südhof	VERB
fnp-2920	175	8	tc	tc	X
fnp-2920	175	9	(	(	PUNCT
fnp-2920	175	10	2018	2018	NUM
fnp-2920	175	11	)	)	PUNCT
fnp-2920	175	12	cell	cell	NOUN
fnp-2920	175	13	biology	biology	NOUN
fnp-2920	175	14	and	and	CCONJ
fnp-2920	175	15	pathophysiology	pathophysiology	NOUN
fnp-2920	175	16	of	of	ADP
fnp-2920	175	17	α	α	NOUN
fnp-2920	175	18	-	-	PUNCT
fnp-2920	175	19	synuclein	synuclein	NOUN
fnp-2920	175	20	.	.	PUNCT
fnp-2920	176	1	cold	cold	ADJ
fnp-2920	176	2	spring	spring	NOUN
fnp-2920	176	3	harb	harb	PROPN
fnp-2920	176	4	perspect	perspect	VERB
fnp-2920	176	5	med	med	PROPN
fnp-2920	176	6	8(3):a024091	8(3):a024091	NUM
fnp-2920	176	7	.	.	PUNCT
fnp-2920	177	1	https://doi.org/10.1101/cshperspect.a024091	https://doi.org/10.1101/cshperspect.a024091	PROPN
fnp-2920	177	2	14	14	NUM
fnp-2920	177	3	.	.	PUNCT
fnp-2920	178	1	bartels	bartels	PROPN
fnp-2920	178	2	t	t	PROPN
fnp-2920	178	3	,	,	PUNCT
fnp-2920	178	4	choi	choi	PROPN
fnp-2920	178	5	jg	jg	PROPN
fnp-2920	178	6	,	,	PUNCT
fnp-2920	178	7	selkoe	selkoe	ADJ
fnp-2920	178	8	dj	dj	X
fnp-2920	178	9	(	(	PUNCT
fnp-2920	178	10	2011	2011	NUM
fnp-2920	178	11	)	)	PUNCT
fnp-2920	178	12	α	α	X
fnp-2920	178	13	-	-	PUNCT
fnp-2920	178	14	synuclein	synuclein	NOUN
fnp-2920	178	15	occurs	occur	VERB
fnp-2920	178	16	physiologically	physiologically	ADV
fnp-2920	178	17	as	as	ADP
fnp-2920	178	18	a	a	DET
fnp-2920	178	19	helically	helically	ADV
fnp-2920	178	20	folded	fold	VERB
fnp-2920	178	21	tetramer	tetramer	PROPN
fnp-2920	178	22	that	that	SCONJ
fnp-2920	178	23	resists	resist	VERB
fnp-2920	178	24	aggregation	aggregation	NOUN
fnp-2920	178	25	.	.	PUNCT
fnp-2920	179	1	nature	nature	PROPN
fnp-2920	179	2	477:107–110	477:107–110	PROPN
fnp-2920	179	3	.	.	PUNCT
fnp-2920	180	1	ttps://doi.org/10.1038/nature10324	ttps://doi.org/10.1038/nature10324	ADJ
fnp-2920	180	2	15	15	NUM
fnp-2920	180	3	.	.	PUNCT
fnp-2920	181	1	fauvet	fauvet	PROPN
fnp-2920	181	2	b	b	PROPN
fnp-2920	181	3	,	,	PUNCT
fnp-2920	181	4	mbefo	mbefo	PROPN
fnp-2920	181	5	mk	mk	PROPN
fnp-2920	181	6	,	,	PUNCT
fnp-2920	181	7	fares	fare	NOUN
fnp-2920	181	8	m	m	PROPN
fnp-2920	181	9	-	-	PUNCT
fnp-2920	181	10	b	b	PROPN
fnp-2920	181	11	,	,	PUNCT
fnp-2920	181	12	et	et	PROPN
fnp-2920	181	13	al	al	PROPN
fnp-2920	181	14	(	(	PUNCT
fnp-2920	181	15	2012	2012	NUM
fnp-2920	181	16	)	)	PUNCT
fnp-2920	182	1	α	α	X
fnp-2920	182	2	-	-	PUNCT
fnp-2920	182	3	synuclein	synuclein	NOUN
fnp-2920	182	4	in	in	ADP
fnp-2920	182	5	central	central	ADJ
fnp-2920	182	6	nervous	nervous	ADJ
fnp-2920	182	7	system	system	NOUN
fnp-2920	182	8	and	and	CCONJ
fnp-2920	182	9	from	from	ADP
fnp-2920	182	10	erythrocytes	erythrocytes	ADJ
fnp-2920	182	11	,	,	PUNCT
fnp-2920	182	12	mammalian	mammalian	ADJ
fnp-2920	182	13	cells	cell	NOUN
fnp-2920	182	14	,	,	PUNCT
fnp-2920	182	15	and	and	CCONJ
fnp-2920	182	16	escherichia	escherichia	NOUN
fnp-2920	182	17	coli	coli	NOUN
fnp-2920	182	18	exists	exist	VERB
fnp-2920	182	19	predominantly	predominantly	ADV
fnp-2920	182	20	as	as	ADP
fnp-2920	182	21	disordered	disordered	ADJ
fnp-2920	182	22	monomer	monomer	NOUN
fnp-2920	182	23	.	.	PUNCT
fnp-2920	183	1	j	j	PROPN
fnp-2920	183	2	biol	biol	PROPN
fnp-2920	183	3	chem	chem	NOUN
fnp-2920	183	4	287:15345–15364	287:15345–15364	NOUN
fnp-2920	183	5	.	.	PUNCT
fnp-2920	184	1	https://doi.org/10.1074/jbc.m111.318949	https://doi.org/10.1074/jbc.m111.318949	PROPN
fnp-2920	184	2	16	16	NUM
fnp-2920	184	3	.	.	PUNCT
fnp-2920	185	1	conway	conway	PROPN
fnp-2920	185	2	ka	ka	PROPN
fnp-2920	185	3	,	,	PUNCT
fnp-2920	185	4	harper	harper	PROPN
fnp-2920	185	5	jd	jd	PROPN
fnp-2920	185	6	,	,	PUNCT
fnp-2920	185	7	lansbury	lansbury	PROPN
fnp-2920	185	8	pt	pt	PROPN
fnp-2920	185	9	(	(	PUNCT
fnp-2920	185	10	2000	2000	NUM
fnp-2920	185	11	)	)	PUNCT
fnp-2920	185	12	fibrils	fibril	NOUN
fnp-2920	185	13	formed	form	VERB
fnp-2920	185	14	in	in	ADP
fnp-2920	185	15	vitro	vitro	X
fnp-2920	185	16	from	from	ADP
fnp-2920	185	17	alpha	alpha	NOUN
fnp-2920	185	18	-	-	PUNCT
fnp-2920	185	19	synuclein	synuclein	NOUN
fnp-2920	185	20	and	and	CCONJ
fnp-2920	185	21	two	two	NUM
fnp-2920	185	22	mutant	mutant	ADJ
fnp-2920	185	23	forms	form	NOUN
fnp-2920	185	24	linked	link	VERB
fnp-2920	185	25	to	to	ADP
fnp-2920	185	26	parkinson	parkinson	NOUN
fnp-2920	185	27	’s	’s	PART
fnp-2920	185	28	disease	disease	NOUN
fnp-2920	185	29	are	be	AUX
fnp-2920	185	30	typical	typical	ADJ
fnp-2920	185	31	amyloid	amyloid	NOUN
fnp-2920	185	32	.	.	PUNCT
fnp-2920	186	1	biochemistry	biochemistry	PROPN
fnp-2920	186	2	39:2552–2563	39:2552–2563	PROPN
fnp-2920	186	3	.	.	PUNCT
fnp-2920	187	1	https://doi.org/10.1021/bi991447r	https://doi.org/10.1021/bi991447r	PROPN
fnp-2920	187	2	17	17	NUM
fnp-2920	187	3	.	.	PUNCT
fnp-2920	188	1	sharrad	sharrad	PROPN
fnp-2920	188	2	df	df	PROPN
fnp-2920	188	3	,	,	PUNCT
fnp-2920	188	4	de	de	PROPN
fnp-2920	188	5	vries	vries	PROPN
fnp-2920	188	6	e	e	PROPN
fnp-2920	188	7	,	,	PUNCT
fnp-2920	188	8	brookes	brook	VERB
fnp-2920	188	9	sjh	sjh	PROPN
fnp-2920	188	10	(	(	PUNCT
fnp-2920	188	11	2013	2013	NUM
fnp-2920	188	12	)	)	PUNCT
fnp-2920	188	13	selective	selective	ADJ
fnp-2920	188	14	expression	expression	NOUN
fnp-2920	188	15	of	of	ADP
fnp-2920	188	16	α	α	NOUN
fnp-2920	188	17	-	-	PUNCT
fnp-2920	188	18	synuclein	synuclein	NOUN
fnp-2920	188	19	-	-	PUNCT
fnp-2920	188	20	immunoreactivity	immunoreactivity	NOUN
fnp-2920	188	21	in	in	ADP
fnp-2920	188	22	vesicular	vesicular	ADJ
fnp-2920	188	23	acetylcholine	acetylcholine	NOUN
fnp-2920	188	24	transporter	transporter	NOUN
fnp-2920	188	25	-	-	PUNCT
fnp-2920	188	26	immunoreactive	immunoreactive	ADJ
fnp-2920	188	27	axons	axon	NOUN
fnp-2920	188	28	in	in	ADP
fnp-2920	188	29	the	the	DET
fnp-2920	188	30	guinea	guinea	NOUN
fnp-2920	188	31	pig	pig	NOUN
fnp-2920	188	32	rectum	rectum	NOUN
fnp-2920	188	33	and	and	CCONJ
fnp-2920	188	34	human	human	ADJ
fnp-2920	188	35	colon	colon	NOUN
fnp-2920	188	36	.	.	PUNCT
fnp-2920	189	1	j	j	PROPN
fnp-2920	189	2	comp	comp	PROPN
fnp-2920	189	3	neurol	neurol	PROPN
fnp-2920	189	4	521:657–676	521:657–676	NUM
fnp-2920	189	5	.	.	PUNCT
fnp-2920	190	1	https://doi.org/10.1002/cne.23198	https://doi.org/10.1002/cne.23198	NOUN
fnp-2920	190	2	18	18	NUM
fnp-2920	190	3	.	.	PUNCT
fnp-2920	191	1	phillips	phillips	PROPN
fnp-2920	191	2	rj	rj	PROPN
fnp-2920	191	3	,	,	PUNCT
fnp-2920	191	4	walter	walter	PROPN
fnp-2920	191	5	gc	gc	PROPN
fnp-2920	191	6	,	,	PUNCT
fnp-2920	191	7	wilder	wilder	ADJ
fnp-2920	191	8	sl	sl	NOUN
fnp-2920	191	9	,	,	PUNCT
fnp-2920	191	10	et	et	PROPN
fnp-2920	191	11	al	al	PROPN
fnp-2920	191	12	(	(	PUNCT
fnp-2920	191	13	2008	2008	NUM
fnp-2920	191	14	)	)	PUNCT
fnp-2920	191	15	alpha	alpha	NOUN
fnp-2920	191	16	-	-	PUNCT
fnp-2920	191	17	synuclein	synuclein	NOUN
fnp-2920	191	18	-	-	PUNCT
fnp-2920	191	19	immunopositive	immunopositive	ADJ
fnp-2920	191	20	myenteric	myenteric	ADJ
fnp-2920	191	21	neurons	neuron	NOUN
fnp-2920	191	22	and	and	CCONJ
fnp-2920	191	23	vagal	vagal	ADJ
fnp-2920	191	24	preganglionic	preganglionic	ADJ
fnp-2920	191	25	terminals	terminal	NOUN
fnp-2920	191	26	:	:	PUNCT
fnp-2920	191	27	autonomic	autonomic	ADJ
fnp-2920	191	28	pathway	pathway	NOUN
fnp-2920	191	29	implicated	implicate	VERB
fnp-2920	191	30	in	in	ADP
fnp-2920	191	31	parkinson	parkinson	NOUN
fnp-2920	191	32	’s	’s	PART
fnp-2920	191	33	disease	disease	NOUN
fnp-2920	191	34	?	?	PUNCT
fnp-2920	192	1	neuroscience	neuroscience	NOUN
fnp-2920	192	2	153:733–750	153:733–750	NUM
fnp-2920	192	3	.	.	PUNCT
fnp-2920	193	1	https://doi.org/10.1016/j.neuroscience.2008.02.074	https://doi.org/10.1016/j.neuroscience.2008.02.074	ADJ
fnp-2920	193	2	19	19	NUM
fnp-2920	193	3	.	.	NUM
fnp-2920	193	4	corbillé	corbillé	VERB
fnp-2920	193	5	a	a	DET
fnp-2920	193	6	-	-	PUNCT
fnp-2920	193	7	g	g	NOUN
fnp-2920	193	8	,	,	PUNCT
fnp-2920	193	9	neunlist	neunlist	NOUN
fnp-2920	193	10	m	m	PROPN
fnp-2920	193	11	,	,	PUNCT
fnp-2920	193	12	derkinderen	derkinderen	VERB
fnp-2920	193	13	p	p	PROPN
fnp-2920	193	14	(	(	PUNCT
fnp-2920	193	15	2016	2016	NUM
fnp-2920	193	16	)	)	PUNCT
fnp-2920	193	17	cross	cross	NOUN
fnp-2920	193	18	-	-	ADJ
fnp-2920	193	19	linking	link	VERB
fnp-2920	193	20	for	for	ADP
fnp-2920	193	21	the	the	DET
fnp-2920	193	22	analysis	analysis	NOUN
fnp-2920	193	23	of	of	ADP
fnp-2920	193	24	α	α	NOUN
fnp-2920	193	25	-	-	PUNCT
fnp-2920	193	26	synuclein	synuclein	NOUN
fnp-2920	193	27	in	in	ADP
fnp-2920	193	28	the	the	DET
fnp-2920	193	29	enteric	enteric	ADJ
fnp-2920	193	30	nervous	nervous	ADJ
fnp-2920	193	31	system	system	NOUN
fnp-2920	193	32	.	.	PUNCT
fnp-2920	194	1	j	j	PROPN
fnp-2920	194	2	neurochem	neurochem	PROPN
fnp-2920	194	3	139:839–847	139:839–847	NUM
fnp-2920	194	4	.	.	PUNCT
fnp-2920	195	1	https://doi.org/10.1111/jnc.13845	https://doi.org/10.1111/jnc.13845	NOUN
fnp-2920	195	2	20	20	NUM
fnp-2920	195	3	.	.	PUNCT
fnp-2920	196	1	böttner	böttner	PROPN
fnp-2920	196	2	m	m	PROPN
fnp-2920	196	3	,	,	PUNCT
fnp-2920	196	4	fricke	fricke	PROPN
fnp-2920	196	5	t	t	PROPN
fnp-2920	196	6	,	,	PUNCT
fnp-2920	196	7	müller	müller	PROPN
fnp-2920	196	8	m	m	PROPN
fnp-2920	196	9	,	,	PUNCT
fnp-2920	196	10	et	et	PROPN
fnp-2920	196	11	al	al	PROPN
fnp-2920	196	12	(	(	PUNCT
fnp-2920	196	13	2015	2015	NUM
fnp-2920	196	14	)	)	PUNCT
fnp-2920	196	15	alpha	alpha	NOUN
fnp-2920	196	16	-	-	PUNCT
fnp-2920	196	17	synuclein	synuclein	NOUN
fnp-2920	196	18	is	be	AUX
fnp-2920	196	19	associated	associate	VERB
fnp-2920	196	20	with	with	ADP
fnp-2920	196	21	the	the	DET
fnp-2920	196	22	synaptic	synaptic	ADJ
fnp-2920	196	23	vesicle	vesicle	NOUN
fnp-2920	196	24	apparatus	apparatus	NOUN
fnp-2920	196	25	in	in	ADP
fnp-2920	196	26	the	the	DET
fnp-2920	196	27	human	human	ADJ
fnp-2920	196	28	and	and	CCONJ
fnp-2920	196	29	rat	rat	NOUN
fnp-2920	196	30	enteric	enteric	ADJ
fnp-2920	196	31	nervous	nervous	ADJ
fnp-2920	196	32	system	system	NOUN
fnp-2920	196	33	.	.	PUNCT
fnp-2920	197	1	brain	brain	NOUN
fnp-2920	197	2	res	re	NOUN
fnp-2920	197	3	1614:51–59	1614:51–59	PROPN
fnp-2920	197	4	.	.	PUNCT
fnp-2920	198	1	https://doi.org/10.1016/j.brainres.2015.04.015	https://doi.org/10.1016/j.brainres.2015.04.015	PROPN
fnp-2920	198	2	21	21	NUM
fnp-2920	198	3	.	.	PUNCT
fnp-2920	199	1	swaminathan	swaminathan	PROPN
fnp-2920	199	2	m	m	PROPN
fnp-2920	199	3	,	,	PUNCT
fnp-2920	199	4	fung	fung	PROPN
fnp-2920	199	5	c	c	PROPN
fnp-2920	199	6	,	,	PUNCT
fnp-2920	199	7	finkelstein	finkelstein	PROPN
fnp-2920	199	8	di	di	PROPN
fnp-2920	199	9	,	,	PUNCT
fnp-2920	199	10	et	et	PROPN
fnp-2920	199	11	al	al	PROPN
fnp-2920	199	12	(	(	PUNCT
fnp-2920	199	13	2019	2019	NUM
fnp-2920	199	14	)	)	PUNCT
fnp-2920	199	15	α	α	X
fnp-2920	199	16	-	-	PUNCT
fnp-2920	199	17	synuclein	synuclein	NOUN
fnp-2920	199	18	regulates	regulate	VERB
fnp-2920	199	19	development	development	NOUN
fnp-2920	199	20	and	and	CCONJ
fnp-2920	199	21	function	function	NOUN
fnp-2920	199	22	of	of	ADP
fnp-2920	199	23	cholinergic	cholinergic	ADJ
fnp-2920	199	24	enteric	enteric	ADJ
fnp-2920	199	25	neurons	neuron	NOUN
fnp-2920	199	26	in	in	ADP
fnp-2920	199	27	the	the	DET
fnp-2920	199	28	mouse	mouse	NOUN
fnp-2920	199	29	colon	colon	NOUN
fnp-2920	199	30	.	.	PUNCT
fnp-2920	200	1	neuroscience	neuroscience	PROPN
fnp-2920	200	2	423:76–85	423:76–85	PROPN
fnp-2920	200	3	.	.	PUNCT
fnp-2920	201	1	https://doi.org/10.1016/j.neuroscience.2019.10.029	https://doi.org/10.1016/j.neuroscience.2019.10.029	PROPN
fnp-2920	201	2	22	22	NUM
fnp-2920	201	3	.	.	PUNCT
fnp-2920	202	1	spillantini	spillantini	PROPN
fnp-2920	202	2	mg	mg	PROPN
fnp-2920	202	3	,	,	PUNCT
fnp-2920	202	4	schmidt	schmidt	PROPN
fnp-2920	202	5	ml	ml	PROPN
fnp-2920	202	6	,	,	PUNCT
fnp-2920	202	7	lee	lee	PROPN
fnp-2920	202	8	vm	vm	PROPN
fnp-2920	202	9	,	,	PUNCT
fnp-2920	202	10	et	et	PROPN
fnp-2920	202	11	al	al	PROPN
fnp-2920	202	12	(	(	PUNCT
fnp-2920	202	13	1997	1997	NUM
fnp-2920	202	14	)	)	PUNCT
fnp-2920	202	15	alpha	alpha	NOUN
fnp-2920	202	16	-	-	PUNCT
fnp-2920	202	17	synuclein	synuclein	NOUN
fnp-2920	202	18	in	in	ADP
fnp-2920	202	19	lewy	lewy	PROPN
fnp-2920	202	20	bodies	body	NOUN
fnp-2920	202	21	.	.	PUNCT
fnp-2920	203	1	nature	nature	NOUN
fnp-2920	203	2	388:839–840	388:839–840	NUM
fnp-2920	203	3	.	.	PUNCT
fnp-2920	204	1	https://doi.org/10.1038/42166	https://doi.org/10.1038/42166	ADV
fnp-2920	204	2	23	23	NUM
fnp-2920	204	3	.	.	PUNCT
fnp-2920	205	1	fujiwara	fujiwara	PROPN
fnp-2920	205	2	h	h	PROPN
fnp-2920	205	3	,	,	PUNCT
fnp-2920	205	4	hasegawa	hasegawa	PROPN
fnp-2920	205	5	m	m	PROPN
fnp-2920	205	6	,	,	PUNCT
fnp-2920	205	7	dohmae	dohmae	PROPN
fnp-2920	205	8	n	n	PRON
fnp-2920	205	9	,	,	PUNCT
fnp-2920	205	10	et	et	PROPN
fnp-2920	205	11	al	al	PROPN
fnp-2920	205	12	(	(	PUNCT
fnp-2920	205	13	2002	2002	NUM
fnp-2920	205	14	)	)	PUNCT
fnp-2920	205	15	alpha	alpha	NOUN
fnp-2920	205	16	-	-	PUNCT
fnp-2920	205	17	synuclein	synuclein	NOUN
fnp-2920	205	18	is	be	AUX
fnp-2920	205	19	phosphorylated	phosphorylate	VERB
fnp-2920	205	20	in	in	ADP
fnp-2920	205	21	synucleinopathy	synucleinopathy	ADJ
fnp-2920	205	22	lesions	lesion	NOUN
fnp-2920	205	23	.	.	PUNCT
fnp-2920	206	1	nat	nat	NOUN
fnp-2920	206	2	cell	cell	NOUN
fnp-2920	206	3	biol	biol	PROPN
fnp-2920	206	4	4:160–164	4:160–164	NOUN
fnp-2920	206	5	.	.	PUNCT
fnp-2920	207	1	https://doi.org/10.1038/ncb748	https://doi.org/10.1038/ncb748	PROPN
fnp-2920	207	2	24	24	NUM
fnp-2920	207	3	.	.	PUNCT
fnp-2920	208	1	kuusisto	kuusisto	PROPN
fnp-2920	208	2	e	e	PROPN
fnp-2920	208	3	,	,	PUNCT
fnp-2920	208	4	parkkinen	parkkinen	NOUN
fnp-2920	208	5	l	l	PROPN
fnp-2920	208	6	,	,	PUNCT
fnp-2920	208	7	alafuzoff	alafuzoff	NOUN
fnp-2920	209	1	i	i	PRON
fnp-2920	209	2	(	(	PUNCT
fnp-2920	209	3	2003	2003	NUM
fnp-2920	209	4	)	)	PUNCT
fnp-2920	209	5	morphogenesis	morphogenesis	NOUN
fnp-2920	209	6	of	of	ADP
fnp-2920	209	7	lewy	lewy	ADJ
fnp-2920	209	8	bodies	body	NOUN
fnp-2920	209	9	:	:	PUNCT
fnp-2920	209	10	dissimilar	dissimilar	ADJ
fnp-2920	209	11	incorporation	incorporation	NOUN
fnp-2920	209	12	of	of	ADP
fnp-2920	209	13	alpha	alpha	NOUN
fnp-2920	209	14	-	-	PUNCT
fnp-2920	209	15	synuclein	synuclein	NOUN
fnp-2920	209	16	,	,	PUNCT
fnp-2920	209	17	ubiquitin	ubiquitin	ADJ
fnp-2920	209	18	,	,	PUNCT
fnp-2920	209	19	and	and	CCONJ
fnp-2920	209	20	p62	p62	NOUN
fnp-2920	209	21	.	.	PUNCT
fnp-2920	210	1	j	j	PROPN
fnp-2920	210	2	neuropathol	neuropathol	PROPN
fnp-2920	210	3	exp	exp	PROPN
fnp-2920	210	4	neurol	neurol	PROPN
fnp-2920	210	5	62:1241–1253	62:1241–1253	NUM
fnp-2920	210	6	.	.	PUNCT
fnp-2920	210	7	https://doi.org/10.1093/jnen/62.12.1241	https://doi.org/10.1093/jnen/62.12.1241	PROPN
fnp-2920	211	1	25	25	NUM
fnp-2920	211	2	.	.	PUNCT
fnp-2920	211	3	beach	beach	PROPN
fnp-2920	211	4	tg	tg	PROPN
fnp-2920	211	5	,	,	PUNCT
fnp-2920	211	6	white	white	ADJ
fnp-2920	211	7	cl	cl	NOUN
fnp-2920	211	8	,	,	PUNCT
fnp-2920	211	9	hamilton	hamilton	PROPN
fnp-2920	211	10	rl	rl	PROPN
fnp-2920	211	11	,	,	PUNCT
fnp-2920	211	12	et	et	PROPN
fnp-2920	211	13	al	al	PROPN
fnp-2920	211	14	(	(	PUNCT
fnp-2920	211	15	2008	2008	NUM
fnp-2920	211	16	)	)	PUNCT
fnp-2920	211	17	evaluation	evaluation	NOUN
fnp-2920	211	18	of	of	ADP
fnp-2920	211	19	alpha	alpha	NOUN
fnp-2920	211	20	-	-	PUNCT
fnp-2920	211	21	synuclein	synuclein	NOUN
fnp-2920	211	22	immunohistochemical	immunohistochemical	ADJ
fnp-2920	211	23	methods	method	NOUN
fnp-2920	211	24	used	use	VERB
fnp-2920	211	25	by	by	ADP
fnp-2920	211	26	invited	invite	VERB
fnp-2920	211	27	experts	expert	NOUN
fnp-2920	211	28	.	.	PUNCT
fnp-2920	212	1	acta	acta	PROPN
fnp-2920	212	2	neuropathol	neuropathol	PROPN
fnp-2920	212	3	116:277–288	116:277–288	NUM
fnp-2920	212	4	.	.	PUNCT
fnp-2920	213	1	https://doi.org/10.1007/s00401-008-0409-8	https://doi.org/10.1007/s00401-008-0409-8	PRON
fnp-2920	213	2	26	26	NUM
fnp-2920	213	3	.	.	PUNCT
fnp-2920	214	1	muntané	muntané	VERB
fnp-2920	214	2	g	g	PROPN
fnp-2920	214	3	,	,	PUNCT
fnp-2920	214	4	ferrer	ferrer	PROPN
fnp-2920	214	5	i	i	PROPN
fnp-2920	214	6	,	,	PUNCT
fnp-2920	214	7	martinez	martinez	PROPN
fnp-2920	214	8	-	-	PUNCT
fnp-2920	214	9	vicente	vicente	PROPN
fnp-2920	214	10	m	m	PROPN
fnp-2920	214	11	(	(	PUNCT
fnp-2920	214	12	2012	2012	NUM
fnp-2920	214	13	)	)	PUNCT
fnp-2920	214	14	α	α	X
fnp-2920	214	15	-	-	PUNCT
fnp-2920	214	16	synuclein	synuclein	NOUN
fnp-2920	214	17	phosphorylation	phosphorylation	NOUN
fnp-2920	214	18	and	and	CCONJ
fnp-2920	214	19	truncation	truncation	NOUN
fnp-2920	214	20	are	be	AUX
fnp-2920	214	21	normal	normal	ADJ
fnp-2920	214	22	events	event	NOUN
fnp-2920	214	23	in	in	ADP
fnp-2920	214	24	the	the	DET
fnp-2920	214	25	adult	adult	NOUN
fnp-2920	214	26	human	human	ADJ
fnp-2920	214	27	brain	brain	NOUN
fnp-2920	214	28	.	.	PUNCT
fnp-2920	215	1	neuroscience	neuroscience	NOUN
fnp-2920	215	2	200:106–119	200:106–119	NUM
fnp-2920	215	3	.	.	PUNCT
fnp-2920	216	1	https://doi.org/10.1016/j.neuroscience.2011.10.042	https://doi.org/10.1016/j.neuroscience.2011.10.042	ADJ
fnp-2920	216	2	27	27	NUM
fnp-2920	216	3	.	.	PUNCT
fnp-2920	217	1	anderson	anderson	PROPN
fnp-2920	217	2	jp	jp	PROPN
fnp-2920	217	3	,	,	PUNCT
fnp-2920	217	4	walker	walker	PROPN
fnp-2920	217	5	de	de	PROPN
fnp-2920	217	6	,	,	PUNCT
fnp-2920	217	7	goldstein	goldstein	PROPN
fnp-2920	217	8	jm	jm	PROPN
fnp-2920	217	9	,	,	PUNCT
fnp-2920	217	10	et	et	PROPN
fnp-2920	217	11	al	al	PROPN
fnp-2920	217	12	(	(	PUNCT
fnp-2920	217	13	2006	2006	NUM
fnp-2920	217	14	)	)	PUNCT
fnp-2920	217	15	phosphorylation	phosphorylation	NOUN
fnp-2920	217	16	of	of	ADP
fnp-2920	217	17	ser-129	ser-129	PROPN
fnp-2920	217	18	is	be	AUX
fnp-2920	217	19	the	the	DET
fnp-2920	217	20	dominant	dominant	ADJ
fnp-2920	217	21	pathological	pathological	ADJ
fnp-2920	217	22	modification	modification	NOUN
fnp-2920	217	23	of	of	ADP
fnp-2920	217	24	alpha	alpha	NOUN
fnp-2920	217	25	-	-	PUNCT
fnp-2920	217	26	synuclein	synuclein	NOUN
fnp-2920	217	27	in	in	ADP
fnp-2920	217	28	familial	familial	ADJ
fnp-2920	217	29	and	and	CCONJ
fnp-2920	217	30	sporadic	sporadic	ADJ
fnp-2920	217	31	lewy	lewy	PROPN
fnp-2920	217	32	body	body	NOUN
fnp-2920	217	33	disease	disease	NOUN
fnp-2920	217	34	.	.	PUNCT
fnp-2920	218	1	j	j	PROPN
fnp-2920	218	2	biol	biol	PROPN
fnp-2920	218	3	chem	chem	NOUN
fnp-2920	218	4	281:29739–29752	281:29739–29752	PRON
fnp-2920	218	5	.	.	PUNCT
fnp-2920	219	1	https://doi.org/10.1074/jbc.m600933200	https://doi.org/10.1074/jbc.m600933200	PRON
fnp-2920	219	2	28	28	NUM
fnp-2920	219	3	.	.	PUNCT
fnp-2920	220	1	jung	jung	PROPN
fnp-2920	220	2	bc	bc	PROPN
fnp-2920	220	3	,	,	PUNCT
fnp-2920	220	4	lim	lim	PROPN
fnp-2920	220	5	y	y	PROPN
fnp-2920	220	6	-	-	PUNCT
fnp-2920	220	7	j	j	PROPN
fnp-2920	220	8	,	,	PUNCT
fnp-2920	220	9	bae	bae	PROPN
fnp-2920	220	10	e	e	PROPN
fnp-2920	220	11	-	-	PROPN
fnp-2920	220	12	j	j	PROPN
fnp-2920	220	13	,	,	PUNCT
fnp-2920	220	14	et	et	PROPN
fnp-2920	220	15	al	al	PROPN
fnp-2920	220	16	(	(	PUNCT
fnp-2920	220	17	2017	2017	NUM
fnp-2920	220	18	)	)	PUNCT
fnp-2920	220	19	amplification	amplification	NOUN
fnp-2920	220	20	of	of	ADP
fnp-2920	220	21	distinct	distinct	ADJ
fnp-2920	220	22	α	α	NOUN
fnp-2920	220	23	-	-	PUNCT
fnp-2920	220	24	synuclein	synuclein	NOUN
fnp-2920	220	25	fibril	fibril	ADJ
fnp-2920	220	26	conformers	conformer	NOUN
fnp-2920	220	27	through	through	ADP
fnp-2920	220	28	protein	protein	NOUN
fnp-2920	220	29	misfolding	misfolde	VERB
fnp-2920	220	30	cyclic	cyclic	ADJ
fnp-2920	220	31	amplification	amplification	NOUN
fnp-2920	220	32	.	.	PUNCT
fnp-2920	221	1	exp	exp	NOUN
fnp-2920	221	2	mol	mol	ADP
fnp-2920	221	3	med	med	PROPN
fnp-2920	221	4	49	49	NUM
fnp-2920	221	5	:	:	PUNCT
fnp-2920	221	6	e314	e314	NUM
fnp-2920	221	7	.	.	PUNCT
fnp-2920	222	1	https://doi.org/10.1038/emm.2017.1	https://doi.org/10.1038/emm.2017.1	PROPN
fnp-2920	222	2	29	29	NUM
fnp-2920	222	3	.	.	PUNCT
fnp-2920	222	4	corbillé	corbillé	VERB
fnp-2920	222	5	a	a	DET
fnp-2920	222	6	-	-	PUNCT
fnp-2920	222	7	g	g	NOUN
fnp-2920	222	8	,	,	PUNCT
fnp-2920	222	9	preterre	preterre	NOUN
fnp-2920	222	10	c	c	NOUN
fnp-2920	222	11	,	,	PUNCT
fnp-2920	222	12	rolli	rolli	ADV
fnp-2920	222	13	-	-	PUNCT
fnp-2920	222	14	derkinderen	derkinderen	NOUN
fnp-2920	222	15	m	m	PROPN
fnp-2920	222	16	,	,	PUNCT
fnp-2920	222	17	et	et	PROPN
fnp-2920	222	18	al	al	PROPN
fnp-2920	222	19	(	(	PUNCT
fnp-2920	222	20	2017	2017	NUM
fnp-2920	222	21	)	)	PUNCT
fnp-2920	222	22	biochemical	biochemical	ADJ
fnp-2920	222	23	analysis	analysis	NOUN
fnp-2920	222	24	of	of	ADP
fnp-2920	222	25	α	α	NOUN
fnp-2920	222	26	-	-	PUNCT
fnp-2920	222	27	synuclein	synuclein	NOUN
fnp-2920	222	28	extracted	extract	VERB
fnp-2920	222	29	from	from	ADP
fnp-2920	222	30	control	control	NOUN
fnp-2920	222	31	and	and	CCONJ
fnp-2920	222	32	parkinson	parkinson	NOUN
fnp-2920	222	33	’s	’s	PART
fnp-2920	222	34	disease	disease	NOUN
fnp-2920	222	35	colonic	colonic	NOUN
fnp-2920	222	36	biopsies	biopsy	NOUN
fnp-2920	222	37	.	.	PUNCT
fnp-2920	223	1	neurosci	neurosci	PROPN
fnp-2920	223	2	lett	lett	PROPN
fnp-2920	223	3	641:81–86	641:81–86	NUM
fnp-2920	223	4	.	.	PUNCT
fnp-2920	224	1	https://doi.org/10.1016/j.neulet.2017.01.050	https://doi.org/10.1016/j.neulet.2017.01.050	PROPN
fnp-2920	224	2	30	30	NUM
fnp-2920	224	3	.	.	PUNCT
fnp-2920	225	1	fenyi	fenyi	PROPN
fnp-2920	225	2	a	a	PRON
fnp-2920	225	3	,	,	PUNCT
fnp-2920	225	4	leclair	leclair	PROPN
fnp-2920	225	5	-	-	PUNCT
fnp-2920	225	6	visonneau	visonneau	NOUN
fnp-2920	225	7	l	l	NOUN
fnp-2920	225	8	,	,	PUNCT
fnp-2920	225	9	clairembault	clairembault	VERB
fnp-2920	225	10	t	t	PROPN
fnp-2920	225	11	,	,	PUNCT
fnp-2920	225	12	et	et	PROPN
fnp-2920	225	13	al	al	PROPN
fnp-2920	225	14	(	(	PUNCT
fnp-2920	225	15	2019	2019	NUM
fnp-2920	225	16	)	)	PUNCT
fnp-2920	225	17	detection	detection	NOUN
fnp-2920	225	18	of	of	ADP
fnp-2920	225	19	alpha	alpha	NOUN
fnp-2920	225	20	-	-	PUNCT
fnp-2920	225	21	synuclein	synuclein	NOUN
fnp-2920	225	22	aggregates	aggregate	NOUN
fnp-2920	225	23	in	in	ADP
fnp-2920	225	24	gastrointestinal	gastrointestinal	ADJ
fnp-2920	225	25	biopsies	biopsy	NOUN
fnp-2920	225	26	by	by	ADP
fnp-2920	225	27	protein	protein	NOUN
fnp-2920	225	28	misfolding	misfolde	VERB
fnp-2920	225	29	cyclic	cyclic	ADJ
fnp-2920	225	30	amplification	amplification	NOUN
fnp-2920	225	31	.	.	PUNCT
fnp-2920	226	1	neurobiol	neurobiol	PROPN
fnp-2920	226	2	dis	dis	PROPN
fnp-2920	227	1	129:38–43	129:38–43	NUM
fnp-2920	227	2	.	.	PUNCT
fnp-2920	227	3	https://doi.org/10.1016/j.nbd.2019.05.002	https://doi.org/10.1016/j.nbd.2019.05.002	PROPN
fnp-2920	227	4	31	31	NUM
fnp-2920	227	5	.	.	PUNCT
fnp-2920	228	1	gray	gray	PROPN
fnp-2920	228	2	mt	mt	PROPN
fnp-2920	228	3	,	,	PUNCT
fnp-2920	228	4	munoz	munoz	PROPN
fnp-2920	228	5	dg	dg	PROPN
fnp-2920	228	6	,	,	PUNCT
fnp-2920	228	7	gray	gray	ADJ
fnp-2920	228	8	da	da	PROPN
fnp-2920	228	9	,	,	PUNCT
fnp-2920	228	10	et	et	PROPN
fnp-2920	228	11	al	al	PROPN
fnp-2920	228	12	(	(	PUNCT
fnp-2920	228	13	2014	2014	NUM
fnp-2920	228	14	)	)	PUNCT
fnp-2920	228	15	alpha	alpha	NOUN
fnp-2920	228	16	-	-	PUNCT
fnp-2920	228	17	synuclein	synuclein	NOUN
fnp-2920	228	18	in	in	ADP
fnp-2920	228	19	the	the	DET
fnp-2920	228	20	appendiceal	appendiceal	ADJ
fnp-2920	228	21	mucosa	mucosa	NOUN
fnp-2920	228	22	of	of	ADP
fnp-2920	228	23	neurologically	neurologically	ADV
fnp-2920	228	24	intact	intact	ADJ
fnp-2920	228	25	subjects	subject	NOUN
fnp-2920	228	26	.	.	PUNCT
fnp-2920	229	1	mov	mov	NOUN
fnp-2920	229	2	disord	disord	NOUN
fnp-2920	229	3	29:991–998	29:991–998	PROPN
fnp-2920	229	4	.	.	PUNCT
fnp-2920	230	1	https://doi.org/10.1002/mds.25779	https://doi.org/10.1002/mds.25779	PROPN
fnp-2920	230	2	32	32	NUM
fnp-2920	230	3	.	.	PUNCT
fnp-2920	231	1	killinger	killinger	PROPN
fnp-2920	231	2	ba	ba	PROPN
fnp-2920	231	3	,	,	PUNCT
fnp-2920	231	4	madaj	madaj	VERB
fnp-2920	231	5	z	z	PROPN
fnp-2920	231	6	,	,	PUNCT
fnp-2920	231	7	sikora	sikora	PROPN
fnp-2920	231	8	jw	jw	PROPN
fnp-2920	231	9	,	,	PUNCT
fnp-2920	231	10	et	et	PROPN
fnp-2920	231	11	al	al	PROPN
fnp-2920	231	12	(	(	PUNCT
fnp-2920	231	13	2018	2018	NUM
fnp-2920	231	14	)	)	PUNCT
fnp-2920	231	15	the	the	DET
fnp-2920	231	16	vermiform	vermiform	ADJ
fnp-2920	231	17	appendix	appendix	NOUN
fnp-2920	231	18	impacts	impact	VERB
fnp-2920	231	19	the	the	DET
fnp-2920	231	20	risk	risk	NOUN
fnp-2920	231	21	of	of	ADP
fnp-2920	231	22	developing	develop	VERB
fnp-2920	231	23	parkinson	parkinson	NOUN
fnp-2920	231	24	’s	’s	PART
fnp-2920	231	25	disease	disease	NOUN
fnp-2920	231	26	.	.	PUNCT
fnp-2920	232	1	sci	sci	PROPN
fnp-2920	232	2	transl	transl	PROPN
fnp-2920	232	3	med	med	PROPN
fnp-2920	232	4	10(465):earr5280	10(465):earr5280	PROPN
fnp-2920	232	5	.	.	PUNCT
fnp-2920	233	1	https://doi.org/10.1126/scitranslmed.aar5280	https://doi.org/10.1126/scitranslmed.aar5280	PROPN
fnp-2920	233	2	33	33	NUM
fnp-2920	233	3	.	.	PUNCT
fnp-2920	234	1	recasens	recasen	NOUN
fnp-2920	234	2	a	a	PRON
fnp-2920	234	3	,	,	PUNCT
fnp-2920	234	4	ulusoy	ulusoy	NOUN
fnp-2920	234	5	a	a	PRON
fnp-2920	234	6	,	,	PUNCT
fnp-2920	234	7	kahle	kahle	PROPN
fnp-2920	234	8	pj	pj	PROPN
fnp-2920	234	9	,	,	PUNCT
fnp-2920	234	10	et	et	PROPN
fnp-2920	234	11	al	al	PROPN
fnp-2920	234	12	(	(	PUNCT
fnp-2920	234	13	2018	2018	NUM
fnp-2920	234	14	)	)	PUNCT
fnp-2920	234	15	in	in	ADP
fnp-2920	234	16	vivo	vivo	NOUN
fnp-2920	234	17	models	model	NOUN
fnp-2920	234	18	of	of	ADP
fnp-2920	234	19	alpha	alpha	NOUN
fnp-2920	234	20	-	-	PUNCT
fnp-2920	234	21	synuclein	synuclein	NOUN
fnp-2920	234	22	transmission	transmission	NOUN
fnp-2920	234	23	and	and	CCONJ
fnp-2920	234	24	propagation	propagation	NOUN
fnp-2920	234	25	.	.	PUNCT
fnp-2920	235	1	cell	cell	NOUN
fnp-2920	235	2	tissue	tissue	NOUN
fnp-2920	235	3	res	re	VERB
fnp-2920	235	4	373:183–193	373:183–193	NUM
fnp-2920	235	5	.	.	PUNCT
fnp-2920	236	1	https://doi.org/10.1007/s00441-017-2730-9	https://doi.org/10.1007/s00441-017-2730-9	VERB
fnp-2920	236	2	34	34	NUM
fnp-2920	236	3	.	.	PUNCT
fnp-2920	237	1	dehay	dehay	PROPN
fnp-2920	237	2	b	b	PROPN
fnp-2920	237	3	,	,	PUNCT
fnp-2920	237	4	vila	vila	PROPN
fnp-2920	237	5	m	m	PROPN
fnp-2920	237	6	,	,	PUNCT
fnp-2920	237	7	bezard	bezard	PROPN
fnp-2920	237	8	e	e	NOUN
fnp-2920	237	9	,	,	PUNCT
fnp-2920	237	10	et	et	PROPN
fnp-2920	237	11	al	al	PROPN
fnp-2920	237	12	(	(	PUNCT
fnp-2920	237	13	2016	2016	NUM
fnp-2920	237	14	)	)	PUNCT
fnp-2920	237	15	alpha	alpha	NOUN
fnp-2920	237	16	-	-	PUNCT
fnp-2920	237	17	synuclein	synuclein	NOUN
fnp-2920	237	18	propagation	propagation	NOUN
fnp-2920	237	19	:	:	PUNCT
fnp-2920	237	20	new	new	ADJ
fnp-2920	237	21	insights	insight	NOUN
fnp-2920	237	22	from	from	ADP
fnp-2920	237	23	animal	animal	NOUN
fnp-2920	237	24	models	model	NOUN
fnp-2920	237	25	.	.	PUNCT
fnp-2920	238	1	mov	mov	NOUN
fnp-2920	238	2	disord	disord	NOUN
fnp-2920	238	3	31:161–168	31:161–168	PROPN
fnp-2920	238	4	.	.	PUNCT
fnp-2920	239	1	https://doi.org/10.1002/mds.26370	https://doi.org/10.1002/mds.26370	PROPN
fnp-2920	239	2	35	35	NUM
fnp-2920	239	3	.	.	PUNCT
fnp-2920	240	1	recasens	recasen	NOUN
fnp-2920	240	2	a	a	PRON
fnp-2920	240	3	,	,	PUNCT
fnp-2920	240	4	dehay	dehay	PROPN
fnp-2920	240	5	b	b	PROPN
fnp-2920	240	6	,	,	PUNCT
fnp-2920	240	7	bové	bové	PROPN
fnp-2920	240	8	j	j	PROPN
fnp-2920	240	9	,	,	PUNCT
fnp-2920	240	10	et	et	PROPN
fnp-2920	240	11	al	al	PROPN
fnp-2920	240	12	(	(	PUNCT
fnp-2920	240	13	2014	2014	NUM
fnp-2920	240	14	)	)	PUNCT
fnp-2920	240	15	lewy	lewy	ADJ
fnp-2920	240	16	body	body	NOUN
fnp-2920	240	17	extracts	extract	NOUN
fnp-2920	240	18	from	from	ADP
fnp-2920	240	19	parkinson	parkinson	NOUN
fnp-2920	240	20	disease	disease	NOUN
fnp-2920	240	21	brains	brain	NOUN
fnp-2920	240	22	trigger	trigger	VERB
fnp-2920	240	23	α	α	NOUN
fnp-2920	240	24	-	-	PUNCT
fnp-2920	240	25	synuclein	synuclein	NOUN
fnp-2920	240	26	pathology	pathology	NOUN
fnp-2920	240	27	and	and	CCONJ
fnp-2920	240	28	neurodegeneration	neurodegeneration	NOUN
fnp-2920	240	29	in	in	ADP
fnp-2920	240	30	mice	mouse	NOUN
fnp-2920	240	31	and	and	CCONJ
fnp-2920	240	32	monkeys	monkey	NOUN
fnp-2920	240	33	.	.	PUNCT
fnp-2920	241	1	ann	ann	PROPN
fnp-2920	241	2	neurol	neurol	PROPN
fnp-2920	241	3	75:351–362	75:351–362	PROPN
fnp-2920	241	4	.	.	PUNCT
fnp-2920	242	1	https://doi.org/10.1002/ana.24066	https://doi.org/10.1002/ana.24066	PROPN
fnp-2920	242	2	36	36	NUM
fnp-2920	242	3	.	.	PUNCT
fnp-2920	243	1	recasens	recasen	NOUN
fnp-2920	243	2	a	a	PRON
fnp-2920	243	3	,	,	PUNCT
fnp-2920	243	4	carballo	carballo	NOUN
fnp-2920	243	5	-	-	PUNCT
fnp-2920	243	6	carbajal	carbajal	NOUN
fnp-2920	243	7	i	i	NOUN
fnp-2920	243	8	,	,	PUNCT
fnp-2920	243	9	parent	parent	PROPN
fnp-2920	243	10	a	a	NOUN
fnp-2920	243	11	,	,	PUNCT
fnp-2920	243	12	et	et	PROPN
fnp-2920	243	13	al	al	PROPN
fnp-2920	243	14	(	(	PUNCT
fnp-2920	243	15	2018	2018	NUM
fnp-2920	243	16	)	)	PUNCT
fnp-2920	243	17	lack	lack	NOUN
fnp-2920	243	18	of	of	ADP
fnp-2920	243	19	pathogenic	pathogenic	ADJ
fnp-2920	243	20	potential	potential	NOUN
fnp-2920	243	21	of	of	ADP
fnp-2920	243	22	peripheral	peripheral	ADJ
fnp-2920	243	23	α	α	NOUN
fnp-2920	243	24	-	-	PUNCT
fnp-2920	243	25	synuclein	synuclein	NOUN
fnp-2920	243	26	aggregates	aggregate	NOUN
fnp-2920	243	27	from	from	ADP
fnp-2920	243	28	parkinson	parkinson	NOUN
fnp-2920	243	29	’s	’s	PART
fnp-2920	243	30	disease	disease	NOUN
fnp-2920	243	31	patients	patient	NOUN
fnp-2920	243	32	.	.	PUNCT
fnp-2920	244	1	acta	acta	PROPN
fnp-2920	244	2	neuropathol	neuropathol	PROPN
fnp-2920	244	3	commun	commun	PROPN
fnp-2920	244	4	6:8	6:8	NUM
fnp-2920	244	5	.	.	PUNCT
fnp-2920	245	1	https://doi.org/10.1186/s40478-018-0509-1	https://doi.org/10.1186/s40478-018-0509-1	NUM
fnp-2920	245	2	37	37	NUM
fnp-2920	245	3	.	.	PUNCT
fnp-2920	245	4	forno	forno	PROPN
fnp-2920	245	5	ls	ls	PROPN
fnp-2920	245	6	,	,	PUNCT
fnp-2920	245	7	norville	norville	PROPN
fnp-2920	245	8	rl	rl	X
fnp-2920	245	9	(	(	PUNCT
fnp-2920	245	10	1976	1976	NUM
fnp-2920	245	11	)	)	PUNCT
fnp-2920	245	12	ultrastructure	ultrastructure	NOUN
fnp-2920	245	13	of	of	ADP
fnp-2920	245	14	lewy	lewy	PROPN
fnp-2920	245	15	bodies	body	NOUN
fnp-2920	245	16	in	in	ADP
fnp-2920	245	17	the	the	DET
fnp-2920	245	18	stellate	stellate	ADJ
fnp-2920	245	19	ganglion	ganglion	NOUN
fnp-2920	245	20	.	.	PUNCT
fnp-2920	246	1	acta	acta	PROPN
fnp-2920	246	2	neuropathol	neuropathol	PROPN
fnp-2920	246	3	34:183–197	34:183–197	PROPN
fnp-2920	246	4	.	.	PUNCT
fnp-2920	247	1	https://doi	https://doi	NOUN
fnp-2920	247	2	.	.	PUNCT
fnp-2920	247	3	org/10.1007	org/10.1007	PROPN
fnp-2920	247	4	/	/	SYM
fnp-2920	247	5	bf00688674	bf00688674	ADJ
fnp-2920	247	6	38	38	NUM
fnp-2920	247	7	.	.	PUNCT
fnp-2920	248	1	del	del	PROPN
fnp-2920	248	2	tredici	tredici	PROPN
fnp-2920	248	3	k	k	PROPN
fnp-2920	248	4	,	,	PUNCT
fnp-2920	248	5	hawkes	hawkes	PROPN
fnp-2920	248	6	ch	ch	PROPN
fnp-2920	248	7	,	,	PUNCT
fnp-2920	248	8	ghebremedhin	ghebremedhin	NOUN
fnp-2920	248	9	e	e	NOUN
fnp-2920	248	10	,	,	PUNCT
fnp-2920	248	11	braak	braak	PROPN
fnp-2920	248	12	h	h	PROPN
fnp-2920	248	13	(	(	PUNCT
fnp-2920	248	14	2010	2010	NUM
fnp-2920	248	15	)	)	PUNCT
fnp-2920	248	16	lewy	lewy	PROPN
fnp-2920	248	17	pathology	pathology	NOUN
fnp-2920	248	18	in	in	ADP
fnp-2920	248	19	the	the	DET
fnp-2920	248	20	submandibular	submandibular	ADJ
fnp-2920	248	21	gland	gland	NOUN
fnp-2920	248	22	of	of	ADP
fnp-2920	248	23	individuals	individual	NOUN
fnp-2920	248	24	with	with	ADP
fnp-2920	248	25	incidental	incidental	ADJ
fnp-2920	248	26	lewy	lewy	ADJ
fnp-2920	248	27	body	body	NOUN
fnp-2920	248	28	disease	disease	NOUN
fnp-2920	248	29	and	and	CCONJ
fnp-2920	248	30	sporadic	sporadic	ADJ
fnp-2920	248	31	parkinson	parkinson	NOUN
fnp-2920	248	32	’s	’s	PART
fnp-2920	248	33	disease	disease	NOUN
fnp-2920	248	34	.	.	PUNCT
fnp-2920	249	1	acta	acta	PROPN
fnp-2920	249	2	neuropathol	neuropathol	PROPN
fnp-2920	249	3	119:703–713	119:703–713	NUM
fnp-2920	249	4	.	.	PUNCT
fnp-2920	250	1	https://doi.org/10.1007/s00401-010-0665-2	https://doi.org/10.1007/s00401-010-0665-2	VERB
fnp-2920	250	2	39	39	NUM
fnp-2920	250	3	.	.	PUNCT
fnp-2920	251	1	greffard	greffard	PROPN
fnp-2920	251	2	s	s	PROPN
fnp-2920	251	3	,	,	PUNCT
fnp-2920	251	4	verny	verny	PROPN
fnp-2920	251	5	m	m	PROPN
fnp-2920	251	6	,	,	PUNCT
fnp-2920	251	7	bonnet	bonnet	VERB
fnp-2920	251	8	a	a	PROPN
fnp-2920	251	9	-	-	PUNCT
fnp-2920	251	10	m	m	NOUN
fnp-2920	251	11	,	,	PUNCT
fnp-2920	251	12	et	et	PROPN
fnp-2920	251	13	al	al	PROPN
fnp-2920	251	14	(	(	PUNCT
fnp-2920	251	15	2006	2006	NUM
fnp-2920	251	16	)	)	PUNCT
fnp-2920	251	17	motor	motor	NOUN
fnp-2920	251	18	score	score	NOUN
fnp-2920	251	19	of	of	ADP
fnp-2920	251	20	the	the	DET
fnp-2920	251	21	unified	unified	ADJ
fnp-2920	251	22	parkinson	parkinson	NOUN
fnp-2920	251	23	disease	disease	NOUN
fnp-2920	251	24	rating	rating	NOUN
fnp-2920	251	25	scale	scale	NOUN
fnp-2920	251	26	as	as	ADP
fnp-2920	251	27	a	a	DET
fnp-2920	251	28	good	good	ADJ
fnp-2920	251	29	predictor	predictor	NOUN
fnp-2920	251	30	of	of	ADP
fnp-2920	251	31	lewy	lewy	PROPN
fnp-2920	251	32	body	body	NOUN
fnp-2920	251	33	-	-	PUNCT
fnp-2920	251	34	associated	associate	VERB
fnp-2920	251	35	neuronal	neuronal	ADJ
fnp-2920	251	36	loss	loss	NOUN
fnp-2920	251	37	in	in	ADP
fnp-2920	251	38	the	the	DET
fnp-2920	251	39	substantia	substantia	NOUN
fnp-2920	251	40	nigra	nigra	NOUN
fnp-2920	251	41	.	.	PUNCT
fnp-2920	252	1	arch	arch	ADJ
fnp-2920	252	2	neurol	neurol	PROPN
fnp-2920	252	3	63:584–588	63:584–588	PROPN
fnp-2920	252	4	.	.	PUNCT
fnp-2920	253	1	https://doi.org/10.1001/archneur	https://doi.org/10.1001/archneur	PROPN
fnp-2920	253	2	.	.	PUNCT
fnp-2920	254	1	63.4.584	63.4.584	NUM
fnp-2920	254	2	40	40	NUM
fnp-2920	254	3	.	.	PUNCT
fnp-2920	255	1	edwards	edwards	PROPN
fnp-2920	255	2	ll	ll	PROPN
fnp-2920	255	3	,	,	PUNCT
fnp-2920	255	4	quigley	quigley	VERB
fnp-2920	255	5	em	em	PRON
fnp-2920	255	6	,	,	PUNCT
fnp-2920	255	7	pfeiffer	pfeiffer	PROPN
fnp-2920	255	8	rf	rf	ADJ
fnp-2920	255	9	(	(	PUNCT
fnp-2920	255	10	1992	1992	NUM
fnp-2920	255	11	)	)	PUNCT
fnp-2920	255	12	gastrointestinal	gastrointestinal	ADJ
fnp-2920	255	13	dysfunction	dysfunction	NOUN
fnp-2920	255	14	in	in	ADP
fnp-2920	255	15	parkinson	parkinson	NOUN
fnp-2920	255	16	’s	’s	PART
fnp-2920	255	17	disease	disease	NOUN
fnp-2920	255	18	:	:	PUNCT
fnp-2920	255	19	frequency	frequency	NOUN
fnp-2920	255	20	and	and	CCONJ
fnp-2920	255	21	pathophysiology	pathophysiology	NOUN
fnp-2920	255	22	.	.	PUNCT
fnp-2920	256	1	neurology	neurology	NOUN
fnp-2920	256	2	42:726–732	42:726–732	PROPN
fnp-2920	256	3	.	.	PUNCT
fnp-2920	257	1	https://doi.org/10.1212/wnl.42.4.726	https://doi.org/10.1212/wnl.42.4.726	PROPN
fnp-2920	257	2	41	41	NUM
fnp-2920	257	3	.	.	PUNCT
fnp-2920	258	1	knowles	knowles	PROPN
fnp-2920	258	2	ch	ch	PROPN
fnp-2920	258	3	,	,	PUNCT
fnp-2920	258	4	de	de	X
fnp-2920	258	5	giorgio	giorgio	PROPN
fnp-2920	258	6	r	r	PROPN
fnp-2920	258	7	,	,	PUNCT
fnp-2920	258	8	kapur	kapur	PROPN
fnp-2920	258	9	rp	rp	PROPN
fnp-2920	258	10	,	,	PUNCT
fnp-2920	258	11	et	et	PROPN
fnp-2920	258	12	al	al	PROPN
fnp-2920	258	13	(	(	PUNCT
fnp-2920	258	14	2009	2009	NUM
fnp-2920	258	15	)	)	PUNCT
fnp-2920	258	16	gastrointestinal	gastrointestinal	ADJ
fnp-2920	258	17	neuromuscular	neuromuscular	ADJ
fnp-2920	258	18	pathology	pathology	NOUN
fnp-2920	258	19	:	:	PUNCT
fnp-2920	258	20	guidelines	guideline	NOUN
fnp-2920	258	21	for	for	ADP
fnp-2920	258	22	histological	histological	ADJ
fnp-2920	258	23	techniques	technique	NOUN
fnp-2920	258	24	and	and	CCONJ
fnp-2920	258	25	reporting	report	VERB
fnp-2920	258	26	on	on	ADP
fnp-2920	258	27	behalf	behalf	NOUN
fnp-2920	258	28	of	of	ADP
fnp-2920	258	29	the	the	DET
fnp-2920	258	30	gastro	gastro	ADJ
fnp-2920	258	31	2009	2009	NUM
fnp-2920	258	32	international	international	ADJ
fnp-2920	258	33	working	working	NOUN
fnp-2920	258	34	group	group	NOUN
fnp-2920	258	35	.	.	PUNCT
fnp-2920	259	1	acta	acta	PROPN
fnp-2920	259	2	neuropathol	neuropathol	PROPN
fnp-2920	259	3	118:271–301	118:271–301	NUM
fnp-2920	259	4	.	.	PUNCT
fnp-2920	260	1	https://doi.org/10.1007/s00401-009-0527-y	https://doi.org/10.1007/s00401-009-0527-y	PROPN
fnp-2920	260	2	42	42	NUM
fnp-2920	260	3	.	.	PUNCT
fnp-2920	261	1	annerino	annerino	PROPN
fnp-2920	261	2	dm	dm	PROPN
fnp-2920	261	3	,	,	PUNCT
fnp-2920	261	4	arshad	arshad	PROPN
fnp-2920	261	5	s	s	PROPN
fnp-2920	261	6	,	,	PUNCT
fnp-2920	261	7	taylor	taylor	PROPN
fnp-2920	261	8	gm	gm	PROPN
fnp-2920	261	9	,	,	PUNCT
fnp-2920	261	10	et	et	PROPN
fnp-2920	261	11	al	al	PROPN
fnp-2920	261	12	(	(	PUNCT
fnp-2920	261	13	2012	2012	NUM
fnp-2920	261	14	)	)	PUNCT
fnp-2920	261	15	parkinson	parkinson	NOUN
fnp-2920	261	16	’s	’s	PART
fnp-2920	261	17	disease	disease	NOUN
fnp-2920	261	18	is	be	AUX
fnp-2920	261	19	not	not	PART
fnp-2920	261	20	associated	associate	VERB
fnp-2920	261	21	with	with	ADP
fnp-2920	261	22	gastrointestinal	gastrointestinal	ADJ
fnp-2920	261	23	myenteric	myenteric	ADJ
fnp-2920	261	24	ganglion	ganglion	NOUN
fnp-2920	261	25	neuron	neuron	PROPN
fnp-2920	261	26	loss	loss	NOUN
fnp-2920	261	27	.	.	PUNCT
fnp-2920	262	1	acta	acta	PROPN
fnp-2920	262	2	neuropathol	neuropathol	PROPN
fnp-2920	262	3	124:665–680	124:665–680	NUM
fnp-2920	262	4	.	.	PUNCT
fnp-2920	263	1	https://doi.org/10.1007/s00401-012-1040-2	https://doi.org/10.1007/s00401-012-1040-2	NUM
fnp-2920	263	2	43	43	NUM
fnp-2920	263	3	.	.	PUNCT
fnp-2920	264	1	giancola	giancola	PROPN
fnp-2920	264	2	f	f	PROPN
fnp-2920	264	3	,	,	PUNCT
fnp-2920	264	4	torresan	torresan	PROPN
fnp-2920	264	5	f	f	X
fnp-2920	264	6	,	,	PUNCT
fnp-2920	264	7	repossi	repossi	ADJ
fnp-2920	264	8	r	r	NOUN
fnp-2920	264	9	,	,	PUNCT
fnp-2920	264	10	et	et	PROPN
fnp-2920	264	11	al	al	PROPN
fnp-2920	264	12	(	(	PUNCT
fnp-2920	264	13	2017	2017	NUM
fnp-2920	264	14	)	)	PUNCT
fnp-2920	264	15	downregulation	downregulation	NOUN
fnp-2920	264	16	of	of	ADP
fnp-2920	264	17	neuronal	neuronal	ADJ
fnp-2920	264	18	vasoactive	vasoactive	ADJ
fnp-2920	264	19	intestinal	intestinal	ADJ
fnp-2920	264	20	polypeptide	polypeptide	NOUN
fnp-2920	264	21	in	in	ADP
fnp-2920	264	22	parkinson	parkinson	NOUN
fnp-2920	264	23	’s	’s	PART
fnp-2920	264	24	disease	disease	NOUN
fnp-2920	264	25	and	and	CCONJ
fnp-2920	264	26	chronic	chronic	ADJ
fnp-2920	264	27	constipation	constipation	NOUN
fnp-2920	264	28	.	.	PUNCT
fnp-2920	265	1	neurogastroenterol	neurogastroenterol	NOUN
fnp-2920	265	2	motil	motil	PROPN
fnp-2920	265	3	29(5):10.1111	29(5):10.1111	PROPN
fnp-2920	265	4	.	.	PUNCT
fnp-2920	266	1	https://doi.org/10.1111/nmo.12995	https://doi.org/10.1111/nmo.12995	PROPN
fnp-2920	266	2	44	44	NUM
fnp-2920	266	3	.	.	PUNCT
fnp-2920	267	1	lionnet	lionnet	PROPN
fnp-2920	267	2	a	a	PROPN
fnp-2920	267	3	,	,	PUNCT
fnp-2920	267	4	wade	wade	PROPN
fnp-2920	267	5	ma	ma	PROPN
fnp-2920	267	6	,	,	PUNCT
fnp-2920	267	7	corbillé	corbillé	VERB
fnp-2920	267	8	a	a	DET
fnp-2920	267	9	-	-	PUNCT
fnp-2920	267	10	g	g	NOUN
fnp-2920	267	11	,	,	PUNCT
fnp-2920	267	12	et	et	PROPN
fnp-2920	267	13	al	al	PROPN
fnp-2920	267	14	(	(	PUNCT
fnp-2920	267	15	2018	2018	NUM
fnp-2920	267	16	)	)	PUNCT
fnp-2920	267	17	characterisation	characterisation	NOUN
fnp-2920	267	18	of	of	ADP
fnp-2920	267	19	tau	tau	PROPN
fnp-2920	267	20	in	in	ADP
fnp-2920	267	21	the	the	DET
fnp-2920	267	22	human	human	ADJ
fnp-2920	267	23	and	and	CCONJ
fnp-2920	267	24	rodent	rodent	ADJ
fnp-2920	267	25	enteric	enteric	ADJ
fnp-2920	267	26	nervous	nervous	ADJ
fnp-2920	267	27	system	system	NOUN
fnp-2920	267	28	under	under	ADP
fnp-2920	267	29	physiological	physiological	ADJ
fnp-2920	267	30	conditions	condition	NOUN
fnp-2920	267	31	and	and	CCONJ
fnp-2920	267	32	in	in	ADP
fnp-2920	267	33	tauopathy	tauopathy	NOUN
fnp-2920	267	34	.	.	PUNCT
fnp-2920	268	1	acta	acta	PROPN
fnp-2920	268	2	neuropathol	neuropathol	PROPN
fnp-2920	268	3	commun	commun	PROPN
fnp-2920	268	4	6:65	6:65	PROPN
fnp-2920	268	5	.	.	PUNCT
fnp-2920	269	1	https://doi.org/10.1186/s40478-018-0568-3	https://doi.org/10.1186/s40478-018-0568-3	NUM
fnp-2920	269	2	45	45	NUM
fnp-2920	269	3	.	.	PUNCT
fnp-2920	270	1	guo	guo	PROPN
fnp-2920	270	2	t	t	PROPN
fnp-2920	270	3	,	,	PUNCT
fnp-2920	270	4	noble	noble	ADJ
fnp-2920	270	5	w	w	NOUN
fnp-2920	270	6	,	,	PUNCT
fnp-2920	270	7	hanger	hanger	NOUN
fnp-2920	270	8	dp	dp	NOUN
fnp-2920	270	9	(	(	PUNCT
fnp-2920	270	10	2017	2017	NUM
fnp-2920	270	11	)	)	PUNCT
fnp-2920	270	12	roles	role	NOUN
fnp-2920	270	13	of	of	ADP
fnp-2920	270	14	tau	tau	PROPN
fnp-2920	270	15	protein	protein	NOUN
fnp-2920	270	16	in	in	ADP
fnp-2920	270	17	health	health	NOUN
fnp-2920	270	18	and	and	CCONJ
fnp-2920	270	19	disease	disease	NOUN
fnp-2920	270	20	.	.	PUNCT
fnp-2920	271	1	acta	acta	PROPN
fnp-2920	271	2	neuropathol	neuropathol	PROPN
fnp-2920	271	3	133:665–704	133:665–704	NUM
fnp-2920	271	4	.	.	PUNCT
fnp-2920	272	1	https://doi.org/10.1007/s00401-017-1707-9	https://doi.org/10.1007/s00401-017-1707-9	NOUN
fnp-2920	272	2	46	46	NUM
fnp-2920	272	3	.	.	PUNCT
fnp-2920	273	1	dugger	dugger	PROPN
fnp-2920	273	2	bn	bn	PROPN
fnp-2920	273	3	,	,	PUNCT
fnp-2920	273	4	hoffman	hoffman	PROPN
fnp-2920	273	5	br	br	PROPN
fnp-2920	273	6	,	,	PUNCT
fnp-2920	273	7	scroggins	scroggins	PROPN
fnp-2920	273	8	a	a	PROPN
fnp-2920	273	9	,	,	PUNCT
fnp-2920	273	10	et	et	PROPN
fnp-2920	273	11	al	al	PROPN
fnp-2920	273	12	(	(	PUNCT
fnp-2920	273	13	2019	2019	NUM
fnp-2920	273	14	)	)	PUNCT
fnp-2920	274	1	tau	tau	PROPN
fnp-2920	274	2	immunoreactivity	immunoreactivity	NOUN
fnp-2920	274	3	in	in	ADP
fnp-2920	274	4	peripheral	peripheral	ADJ
fnp-2920	274	5	tissues	tissue	NOUN
fnp-2920	274	6	of	of	ADP
fnp-2920	274	7	human	human	ADJ
fnp-2920	274	8	aging	aging	NOUN
fnp-2920	274	9	and	and	CCONJ
fnp-2920	274	10	select	select	ADJ
fnp-2920	274	11	tauopathies	tauopathie	NOUN
fnp-2920	274	12	.	.	PUNCT
fnp-2920	275	1	neurosci	neurosci	PROPN
fnp-2920	275	2	lett	lett	PROPN
fnp-2920	275	3	696:132–139	696:132–139	PROPN
fnp-2920	275	4	.	.	PUNCT
fnp-2920	276	1	https://doi.org/10.1016/j.neulet.2018.12.031	https://doi.org/10.1016/j.neulet.2018.12.031	PROPN
fnp-2920	276	2	47	47	NUM
fnp-2920	276	3	.	.	PUNCT
fnp-2920	277	1	ohlsson	ohlsson	PROPN
fnp-2920	277	2	b	b	PROPN
fnp-2920	277	3	,	,	PUNCT
fnp-2920	277	4	englund	englund	PROPN
fnp-2920	277	5	e	e	PROPN
fnp-2920	277	6	(	(	PUNCT
fnp-2920	277	7	2019	2019	NUM
fnp-2920	277	8	)	)	PUNCT
fnp-2920	277	9	atrophic	atrophic	ADJ
fnp-2920	277	10	myenteric	myenteric	ADJ
fnp-2920	277	11	and	and	CCONJ
fnp-2920	277	12	submucosal	submucosal	NOUN
fnp-2920	277	13	neurons	neuron	NOUN
fnp-2920	277	14	are	be	AUX
fnp-2920	277	15	observed	observe	VERB
fnp-2920	277	16	in	in	ADP
fnp-2920	277	17	parkinson	parkinson	NOUN
fnp-2920	277	18	’s	’s	PART
fnp-2920	277	19	disease	disease	NOUN
fnp-2920	277	20	.	.	PUNCT
fnp-2920	278	1	parkinsons	parkinson	NOUN
fnp-2920	278	2	dis	dis	PROPN
fnp-2920	278	3	2019:7935820	2019:7935820	NUM
fnp-2920	278	4	.	.	PUNCT
fnp-2920	279	1	https://doi.org/10.1155/2019/7935820	https://doi.org/10.1155/2019/7935820	NOUN
fnp-2920	279	2	48	48	NUM
fnp-2920	279	3	.	.	PUNCT
fnp-2920	280	1	ozawa	ozawa	PROPN
fnp-2920	280	2	t	t	PROPN
fnp-2920	280	3	,	,	PUNCT
fnp-2920	280	4	shimizu	shimizu	PROPN
fnp-2920	280	5	h	h	PROPN
fnp-2920	280	6	,	,	PUNCT
fnp-2920	280	7	matsui	matsui	PROPN
fnp-2920	280	8	h	h	PROPN
fnp-2920	280	9	,	,	PUNCT
fnp-2920	280	10	et	et	PROPN
fnp-2920	280	11	al	al	PROPN
fnp-2920	280	12	(	(	PUNCT
fnp-2920	280	13	2019	2019	NUM
fnp-2920	280	14	)	)	PUNCT
fnp-2920	280	15	shrinkage	shrinkage	NOUN
fnp-2920	280	16	of	of	ADP
fnp-2920	280	17	the	the	DET
fnp-2920	280	18	myenteric	myenteric	ADJ
fnp-2920	280	19	neurons	neuron	NOUN
fnp-2920	280	20	of	of	ADP
fnp-2920	280	21	the	the	DET
fnp-2920	280	22	small	small	ADJ
fnp-2920	280	23	intestine	intestine	NOUN
fnp-2920	280	24	in	in	ADP
fnp-2920	280	25	patients	patient	NOUN
fnp-2920	280	26	with	with	ADP
fnp-2920	280	27	multiple	multiple	ADJ
fnp-2920	280	28	system	system	NOUN
fnp-2920	280	29	atrophy	atrophy	NOUN
fnp-2920	280	30	.	.	PUNCT
fnp-2920	281	1	auton	auton	PROPN
fnp-2920	281	2	neurosci	neurosci	PROPN
fnp-2920	281	3	221:102583	221:102583	X
fnp-2920	281	4	.	.	PUNCT
fnp-2920	282	1	https://doi.org/10.1016/j.autneu.2019.102583	https://doi.org/10.1016/j.autneu.2019.102583	PROPN
fnp-2920	282	2	49	49	NUM
fnp-2920	282	3	.	.	PUNCT
fnp-2920	283	1	rossi	rossi	PROPN
fnp-2920	283	2	m	m	PROPN
fnp-2920	283	3	,	,	PUNCT
fnp-2920	283	4	candelise	candelise	VERB
fnp-2920	283	5	n	n	CCONJ
fnp-2920	283	6	,	,	PUNCT
fnp-2920	283	7	baiardi	baiardi	PROPN
fnp-2920	283	8	s	s	PART
fnp-2920	283	9	,	,	PUNCT
fnp-2920	283	10	et	et	PROPN
fnp-2920	283	11	al	al	PROPN
fnp-2920	283	12	(	(	PUNCT
fnp-2920	283	13	2020	2020	NUM
fnp-2920	283	14	)	)	PUNCT
fnp-2920	283	15	ultrasensitive	ultrasensitive	ADJ
fnp-2920	283	16	rt	rt	PROPN
fnp-2920	283	17	-	-	PUNCT
fnp-2920	283	18	quic	quic	PROPN
fnp-2920	283	19	assay	assay	VERB
fnp-2920	283	20	with	with	ADP
fnp-2920	283	21	high	high	ADJ
fnp-2920	283	22	sensitivity	sensitivity	NOUN
fnp-2920	283	23	and	and	CCONJ
fnp-2920	283	24	specificity	specificity	NOUN
fnp-2920	283	25	for	for	ADP
fnp-2920	283	26	lewy	lewy	ADJ
fnp-2920	283	27	body	body	NOUN
fnp-2920	283	28	-	-	PUNCT
fnp-2920	283	29	associated	associate	VERB
fnp-2920	283	30	synucleinopathies	synucleinopathie	NOUN
fnp-2920	283	31	.	.	PUNCT
fnp-2920	284	1	acta	acta	PROPN
fnp-2920	284	2	neuropathol	neuropathol	PROPN
fnp-2920	284	3	140:49–62	140:49–62	NUM
fnp-2920	284	4	.	.	PROPN
fnp-2920	285	1	https://doi.org/10.1007/s00401-020-02160-8	https://doi.org/10.1007/s00401-020-02160-8	NUM
fnp-2920	285	2	50	50	NUM
fnp-2920	285	3	.	.	PUNCT
fnp-2920	286	1	arotcarena	arotcarena	PROPN
fnp-2920	286	2	m	m	PROPN
fnp-2920	286	3	-	-	PUNCT
fnp-2920	286	4	l	l	NOUN
fnp-2920	286	5	,	,	PUNCT
fnp-2920	286	6	dovero	dovero	NOUN
fnp-2920	286	7	s	s	PROPN
fnp-2920	286	8	,	,	PUNCT
fnp-2920	286	9	prigent	prigent	NOUN
fnp-2920	286	10	a	a	X
fnp-2920	286	11	,	,	PUNCT
fnp-2920	286	12	et	et	PROPN
fnp-2920	286	13	al	al	PROPN
fnp-2920	286	14	(	(	PUNCT
fnp-2920	286	15	2020	2020	NUM
fnp-2920	286	16	)	)	PUNCT
fnp-2920	286	17	bidirectional	bidirectional	ADJ
fnp-2920	286	18	gut	gut	NOUN
fnp-2920	286	19	-	-	PUNCT
fnp-2920	286	20	to	to	ADP
fnp-2920	286	21	-	-	PUNCT
fnp-2920	286	22	brain	brain	NOUN
fnp-2920	286	23	and	and	CCONJ
fnp-2920	286	24	brain	brain	NOUN
fnp-2920	286	25	-	-	PUNCT
fnp-2920	286	26	to	to	ADP
fnp-2920	286	27	-	-	PUNCT
fnp-2920	286	28	gut	gut	NOUN
fnp-2920	286	29	propagation	propagation	NOUN
fnp-2920	286	30	of	of	ADP
fnp-2920	286	31	synucleinopathy	synucleinopathy	NOUN
fnp-2920	286	32	in	in	ADP
fnp-2920	286	33	non	non	ADJ
fnp-2920	286	34	-	-	ADJ
fnp-2920	286	35	human	human	ADJ
fnp-2920	286	36	primates	primate	NOUN
fnp-2920	286	37	.	.	PUNCT
fnp-2920	287	1	brain	brain	NOUN
fnp-2920	287	2	143:1462–1475	143:1462–1475	NUM
fnp-2920	287	3	.	.	PUNCT
fnp-2920	288	1	https://doi.org/10.1093/brain/awaa096	https://doi.org/10.1093/brain/awaa096	PROPN
fnp-2920	288	2	51	51	NUM
fnp-2920	288	3	.	.	PUNCT
fnp-2920	288	4	beach	beach	PROPN
fnp-2920	288	5	tg	tg	PROPN
fnp-2920	288	6	,	,	PUNCT
fnp-2920	288	7	corbillé	corbillé	VERB
fnp-2920	288	8	a	a	DET
fnp-2920	288	9	-	-	PUNCT
fnp-2920	288	10	g	g	NOUN
fnp-2920	288	11	,	,	PUNCT
fnp-2920	288	12	letournel	letournel	NOUN
fnp-2920	288	13	f	f	PROPN
fnp-2920	288	14	,	,	PUNCT
fnp-2920	288	15	et	et	PROPN
fnp-2920	288	16	al	al	PROPN
fnp-2920	288	17	(	(	PUNCT
fnp-2920	288	18	2016	2016	NUM
fnp-2920	288	19	)	)	PUNCT
fnp-2920	288	20	multicenter	multicenter	ADJ
fnp-2920	288	21	assessment	assessment	NOUN
fnp-2920	288	22	of	of	ADP
fnp-2920	288	23	immunohistochemical	immunohistochemical	ADJ
fnp-2920	288	24	methods	method	NOUN
fnp-2920	288	25	for	for	ADP
fnp-2920	288	26	pathological	pathological	ADJ
fnp-2920	288	27	alpha	alpha	NOUN
fnp-2920	288	28	-	-	PUNCT
fnp-2920	288	29	synuclein	synuclein	NOUN
fnp-2920	288	30	in	in	ADP
fnp-2920	288	31	sigmoid	sigmoid	NOUN
fnp-2920	288	32	colon	colon	NOUN
fnp-2920	288	33	of	of	ADP
fnp-2920	288	34	autopsied	autopsied	ADJ
fnp-2920	288	35	parkinson	parkinson	NOUN
fnp-2920	288	36	’s	’s	PART
fnp-2920	288	37	disease	disease	NOUN
fnp-2920	288	38	and	and	CCONJ
fnp-2920	288	39	control	control	NOUN
fnp-2920	288	40	subjects	subject	NOUN
fnp-2920	288	41	.	.	PUNCT
fnp-2920	289	1	j	j	PROPN
fnp-2920	289	2	parkinsons	parkinson	NOUN
fnp-2920	289	3	dis	dis	PROPN
fnp-2920	289	4	6:761–770	6:761–770	VERB
fnp-2920	289	5	.	.	PUNCT
fnp-2920	290	1	https://doi.org/10.3233/jpd-160888	https://doi.org/10.3233/jpd-160888	X
fnp-2920	290	2	copyright	copyright	NOUN
fnp-2920	290	3	:	:	PUNCT
fnp-2920	290	4	©	©	PROPN
fnp-2920	290	5	2020	2020	NUM
fnp-2920	290	6	the	the	DET
fnp-2920	290	7	author(s	author(s	NOUN
fnp-2920	290	8	)	)	PUNCT
fnp-2920	290	9	.	.	PUNCT
fnp-2920	291	1	this	this	PRON
fnp-2920	291	2	is	be	AUX
fnp-2920	291	3	an	an	DET
fnp-2920	291	4	open	open	ADJ
fnp-2920	291	5	access	access	NOUN
fnp-2920	291	6	article	article	NOUN
fnp-2920	291	7	distributed	distribute	VERB
fnp-2920	291	8	under	under	ADP
fnp-2920	291	9	the	the	DET
fnp-2920	291	10	terms	term	NOUN
fnp-2920	291	11	of	of	ADP
fnp-2920	291	12	the	the	DET
fnp-2920	291	13	creative	creative	ADJ
fnp-2920	291	14	commons	common	NOUN
fnp-2920	291	15	attribution	attribution	NOUN
fnp-2920	291	16	4.0	4.0	NUM
fnp-2920	291	17	international	international	ADJ
fnp-2920	291	18	license	license	NOUN
fnp-2920	291	19	(	(	PUNCT
fnp-2920	291	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-2920	291	21	)	)	PUNCT
fnp-2920	291	22	,	,	PUNCT
fnp-2920	291	23	which	which	PRON
fnp-2920	291	24	permits	permit	VERB
fnp-2920	291	25	unrestricted	unrestricted	ADJ
fnp-2920	291	26	use	use	NOUN
fnp-2920	291	27	,	,	PUNCT
fnp-2920	291	28	distribution	distribution	NOUN
fnp-2920	291	29	,	,	PUNCT
fnp-2920	291	30	and	and	CCONJ
fnp-2920	291	31	reproduction	reproduction	NOUN
fnp-2920	291	32	in	in	ADP
fnp-2920	291	33	any	any	DET
fnp-2920	291	34	medium	medium	NOUN
fnp-2920	291	35	,	,	PUNCT
fnp-2920	291	36	provided	provide	VERB
fnp-2920	291	37	the	the	DET
fnp-2920	291	38	original	original	ADJ
fnp-2920	291	39	author	author	NOUN
fnp-2920	291	40	and	and	CCONJ
fnp-2920	291	41	source	source	NOUN
fnp-2920	291	42	are	be	AUX
fnp-2920	291	43	credited	credit	VERB
fnp-2920	291	44	,	,	PUNCT
fnp-2920	291	45	a	a	DET
fnp-2920	291	46	link	link	NOUN
fnp-2920	291	47	to	to	ADP
fnp-2920	291	48	the	the	DET
fnp-2920	291	49	creative	creative	ADJ
fnp-2920	291	50	commons	common	NOUN
fnp-2920	291	51	license	license	NOUN
fnp-2920	291	52	is	be	AUX
fnp-2920	291	53	provided	provide	VERB
fnp-2920	291	54	,	,	PUNCT
fnp-2920	291	55	and	and	CCONJ
fnp-2920	291	56	any	any	DET
fnp-2920	291	57	changes	change	NOUN
fnp-2920	291	58	are	be	AUX
fnp-2920	291	59	indicated	indicate	VERB
fnp-2920	291	60	.	.	PUNCT
fnp-2920	292	1	the	the	DET
fnp-2920	292	2	creative	creative	ADJ
fnp-2920	292	3	commons	common	NOUN
fnp-2920	292	4	public	public	ADJ
fnp-2920	292	5	domain	domain	NOUN
fnp-2920	292	6	dedication	dedication	NOUN
fnp-2920	292	7	waiver	waiver	NOUN
fnp-2920	292	8	(	(	PUNCT
fnp-2920	292	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-2920	292	10	)	)	PUNCT
fnp-2920	292	11	applies	apply	VERB
fnp-2920	292	12	to	to	ADP
fnp-2920	292	13	the	the	DET
fnp-2920	292	14	data	datum	NOUN
fnp-2920	292	15	made	make	VERB
fnp-2920	292	16	available	available	ADJ
fnp-2920	292	17	in	in	ADP
fnp-2920	292	18	this	this	DET
fnp-2920	292	19	article	article	NOUN
fnp-2920	292	20	,	,	PUNCT
fnp-2920	292	21	unless	unless	SCONJ
fnp-2920	292	22	otherwise	otherwise	ADV
fnp-2920	292	23	stated	state	VERB
fnp-2920	292	24	.	.	PUNCT
