id	sid	tid	token	lemma	pos
fnp-2955	1	1	quantitative	quantitative	ADJ
fnp-2955	1	2	proteomic	proteomic	NOUN
fnp-2955	1	3	profiling	profiling	NOUN
fnp-2955	1	4	of	of	ADP
fnp-2955	1	5	white	white	ADJ
fnp-2955	1	6	matter	matter	NOUN
fnp-2955	1	7	in	in	ADP
fnp-2955	1	8	cases	case	NOUN
fnp-2955	1	9	of	of	ADP
fnp-2955	1	10	cerebral	cerebral	ADJ
fnp-2955	1	11	amyloid	amyloid	NOUN
fnp-2955	1	12	angiopathy	angiopathy	NOUN
fnp-2955	1	13	reveals	reveal	VERB
fnp-2955	1	14	upregulation	upregulation	NOUN
fnp-2955	1	15	of	of	ADP
fnp-2955	1	16	extracellular	extracellular	ADJ
fnp-2955	1	17	matrix	matrix	NOUN
fnp-2955	1	18	proteins	protein	NOUN
fnp-2955	1	19	and	and	CCONJ
fnp-2955	1	20	clusterin	clusterin	NOUN
fnp-2955	1	21	feel	feel	VERB
fnp-2955	1	22	free	free	ADJ
fnp-2955	1	23	to	to	PART
fnp-2955	1	24	add	add	VERB
fnp-2955	1	25	comments	comment	NOUN
fnp-2955	1	26	by	by	ADP
fnp-2955	1	27	clicking	click	VERB
fnp-2955	1	28	these	these	DET
fnp-2955	1	29	icons	icon	NOUN
fnp-2955	1	30	on	on	ADP
fnp-2955	1	31	the	the	DET
fnp-2955	1	32	sidebar	sidebar	NOUN
fnp-2955	1	33	free	free	ADJ
fnp-2955	1	34	neuropathology	neuropathology	NOUN
fnp-2955	1	35	1:28	1:28	NUM
fnp-2955	1	36	(	(	PUNCT
fnp-2955	1	37	2020	2020	NUM
fnp-2955	1	38	)	)	PUNCT
fnp-2955	1	39	original	original	ADJ
fnp-2955	1	40	paper	paper	NOUN
fnp-2955	1	41	quantitative	quantitative	ADJ
fnp-2955	1	42	proteomic	proteomic	NOUN
fnp-2955	1	43	profiling	profiling	NOUN
fnp-2955	1	44	of	of	ADP
fnp-2955	1	45	white	white	ADJ
fnp-2955	1	46	matter	matter	NOUN
fnp-2955	1	47	in	in	ADP
fnp-2955	1	48	cases	case	NOUN
fnp-2955	1	49	of	of	ADP
fnp-2955	1	50	cerebral	cerebral	ADJ
fnp-2955	1	51	amyloid	amyloid	NOUN
fnp-2955	1	52	angiopathy	angiopathy	NOUN
fnp-2955	1	53	reveals	reveal	VERB
fnp-2955	1	54	upregulation	upregulation	NOUN
fnp-2955	1	55	of	of	ADP
fnp-2955	1	56	extracellular	extracellular	ADJ
fnp-2955	1	57	matrix	matrix	NOUN
fnp-2955	1	58	proteins	protein	NOUN
fnp-2955	1	59	and	and	CCONJ
fnp-2955	1	60	clusterin	clusterin	NOUN
fnp-2955	1	61	antigoni	antigoni	PROPN
fnp-2955	1	62	manousopoulou1	manousopoulou1	PROPN
fnp-2955	1	63	*	*	PROPN
fnp-2955	1	64	*	*	PROPN
fnp-2955	1	65	,	,	PUNCT
fnp-2955	1	66	ho	ho	PROPN
fnp-2955	1	67	ming	ming	PROPN
fnp-2955	1	68	yuen2	yuen2	PROPN
fnp-2955	2	1	*	*	PROPN
fnp-2955	2	2	*	*	PROPN
fnp-2955	2	3	,	,	PUNCT
fnp-2955	2	4	matthew	matthew	PROPN
fnp-2955	2	5	macgregor	macgregor	PROPN
fnp-2955	2	6	sharp2	sharp2	PROPN
fnp-2955	2	7	,	,	PUNCT
fnp-2955	2	8	satoshi	satoshi	PROPN
fnp-2955	2	9	saito2	saito2	PROPN
fnp-2955	2	10	,	,	PUNCT
fnp-2955	2	11	roxana	roxana	PROPN
fnp-2955	2	12	aldea3	aldea3	PROPN
fnp-2955	2	13	,	,	PUNCT
fnp-2955	2	14	norman	norman	PROPN
fnp-2955	2	15	mazer3	mazer3	PROPN
fnp-2955	2	16	,	,	PUNCT
fnp-2955	2	17	spiros	spiros	PROPN
fnp-2955	2	18	d.	d.	PROPN
fnp-2955	2	19	garbis4	garbis4	PROPN
fnp-2955	2	20	,	,	PUNCT
fnp-2955	2	21	roxana	roxana	PROPN
fnp-2955	2	22	o.	o.	PROPN
fnp-2955	3	1	carare2	carare2	PROPN
fnp-2955	3	2	*	*	PROPN
fnp-2955	3	3	1	1	NUM
fnp-2955	3	4	beckman	beckman	PROPN
fnp-2955	3	5	research	research	PROPN
fnp-2955	3	6	institute	institute	PROPN
fnp-2955	3	7	,	,	PUNCT
fnp-2955	3	8	city	city	NOUN
fnp-2955	3	9	of	of	ADP
fnp-2955	3	10	hope	hope	PROPN
fnp-2955	3	11	,	,	PUNCT
fnp-2955	3	12	duarte	duarte	PROPN
fnp-2955	3	13	,	,	PUNCT
fnp-2955	3	14	ca	ca	PROPN
fnp-2955	3	15	,	,	PUNCT
fnp-2955	3	16	usa	usa	PROPN
fnp-2955	3	17	2	2	NUM
fnp-2955	3	18	faculty	faculty	NOUN
fnp-2955	3	19	of	of	ADP
fnp-2955	3	20	medicine	medicine	NOUN
fnp-2955	3	21	,	,	PUNCT
fnp-2955	3	22	university	university	PROPN
fnp-2955	3	23	of	of	ADP
fnp-2955	3	24	southampton	southampton	PROPN
fnp-2955	3	25	,	,	PUNCT
fnp-2955	3	26	southampton	southampton	PROPN
fnp-2955	3	27	so16	so16	PROPN
fnp-2955	3	28	6	6	NUM
fnp-2955	3	29	yd	yd	NOUN
fnp-2955	3	30	,	,	PUNCT
fnp-2955	3	31	uk	uk	PROPN
fnp-2955	3	32	3	3	NUM
fnp-2955	3	33	roche	roche	PROPN
fnp-2955	3	34	pharma	pharma	PROPN
fnp-2955	3	35	research	research	NOUN
fnp-2955	3	36	and	and	CCONJ
fnp-2955	3	37	early	early	ADJ
fnp-2955	3	38	development	development	NOUN
fnp-2955	3	39	,	,	PUNCT
fnp-2955	3	40	pharmaceutical	pharmaceutical	NOUN
fnp-2955	3	41	sciences	science	NOUN
fnp-2955	3	42	,	,	PUNCT
fnp-2955	3	43	roche	roche	NOUN
fnp-2955	3	44	innovation	innovation	PROPN
fnp-2955	3	45	center	center	PROPN
fnp-2955	3	46	basel	basel	PROPN
fnp-2955	3	47	,	,	PUNCT
fnp-2955	3	48	f.	f.	PROPN
fnp-2955	3	49	hoffmann	hoffmann	PROPN
fnp-2955	3	50	-	-	PUNCT
fnp-2955	3	51	la	la	PROPN
fnp-2955	3	52	roche	roche	PROPN
fnp-2955	3	53	ltd	ltd	PROPN
fnp-2955	3	54	,	,	PUNCT
fnp-2955	3	55	basel	basel	PROPN
fnp-2955	3	56	,	,	PUNCT
fnp-2955	3	57	switzerland	switzerland	PROPN
fnp-2955	3	58	4	4	NUM
fnp-2955	3	59	proteome	proteome	PROPN
fnp-2955	3	60	exploration	exploration	NOUN
fnp-2955	3	61	laboratory	laboratory	NOUN
fnp-2955	3	62	,	,	PUNCT
fnp-2955	3	63	beckman	beckman	PROPN
fnp-2955	3	64	institute	institute	PROPN
fnp-2955	3	65	,	,	PUNCT
fnp-2955	3	66	division	division	NOUN
fnp-2955	3	67	of	of	ADP
fnp-2955	3	68	biology	biology	NOUN
fnp-2955	3	69	and	and	CCONJ
fnp-2955	3	70	biological	biological	ADJ
fnp-2955	3	71	engineering	engineering	NOUN
fnp-2955	3	72	,	,	PUNCT
fnp-2955	3	73	california	california	PROPN
fnp-2955	3	74	institute	institute	PROPN
fnp-2955	3	75	of	of	ADP
fnp-2955	3	76	technology	technology	PROPN
fnp-2955	3	77	,	,	PUNCT
fnp-2955	3	78	pasadena	pasadena	PROPN
fnp-2955	3	79	,	,	PUNCT
fnp-2955	3	80	ca	ca	PROPN
fnp-2955	3	81	,	,	PUNCT
fnp-2955	3	82	usa	usa	PROPN
fnp-2955	3	83	*	*	PROPN
fnp-2955	3	84	*	*	PUNCT
fnp-2955	3	85	authors	author	NOUN
fnp-2955	3	86	contributed	contribute	VERB
fnp-2955	3	87	equally	equally	ADV
fnp-2955	3	88	corresponding	corresponding	ADJ
fnp-2955	3	89	author	author	NOUN
fnp-2955	3	90	:	:	PUNCT
fnp-2955	3	91	prof	prof	PROPN
fnp-2955	3	92	roxana	roxana	PROPN
fnp-2955	3	93	o	o	PROPN
fnp-2955	3	94	carare	carare	PROPN
fnp-2955	3	95	·	·	PUNCT
fnp-2955	3	96	university	university	NOUN
fnp-2955	3	97	of	of	ADP
fnp-2955	3	98	southampton	southampton	PROPN
fnp-2955	3	99	·	·	PUNCT
fnp-2955	3	100	faculty	faculty	NOUN
fnp-2955	3	101	of	of	ADP
fnp-2955	3	102	medicine	medicine	NOUN
fnp-2955	3	103	·	·	PUNCT
fnp-2955	3	104	southampton	southampton	PROPN
fnp-2955	3	105	general	general	PROPN
fnp-2955	3	106	hospital	hospital	PROPN
fnp-2955	3	107	·	·	PUNCT
fnp-2955	3	108	south	south	ADJ
fnp-2955	3	109	academic	academic	ADJ
fnp-2955	3	110	block	block	NOUN
fnp-2955	3	111	,	,	PUNCT
fnp-2955	3	112	mp806	mp806	X
fnp-2955	3	113	·	·	PUNCT
fnp-2955	3	114	tremona	tremona	PROPN
fnp-2955	3	115	road	road	PROPN
fnp-2955	3	116	·	·	PUNCT
fnp-2955	3	117	southampton	southampton	PROPN
fnp-2955	3	118	,	,	PUNCT
fnp-2955	3	119	hampshire	hampshire	PROPN
fnp-2955	3	120	·	·	PUNCT
fnp-2955	4	1	so16	so16	PROPN
fnp-2955	4	2	6	6	NUM
fnp-2955	4	3	yd	yd	NOUN
fnp-2955	4	4	·	·	PUNCT
fnp-2955	4	5	united	united	ADJ
fnp-2955	4	6	kingdom	kingdom	PROPN
fnp-2955	4	7	r.o.carare@soton.ac.uk	r.o.carare@soton.ac.uk	PROPN
fnp-2955	4	8	submitted	submit	VERB
fnp-2955	4	9	:	:	PUNCT
fnp-2955	4	10	14	14	NUM
fnp-2955	4	11	august	august	PROPN
fnp-2955	4	12	2020	2020	NUM
fnp-2955	4	13	accepted	accept	VERB
fnp-2955	4	14	:	:	PUNCT
fnp-2955	4	15	06	06	NUM
fnp-2955	4	16	october	october	PROPN
fnp-2955	4	17	2020	2020	NUM
fnp-2955	4	18	copyedited	copyedit	VERB
fnp-2955	4	19	by	by	ADP
fnp-2955	4	20	:	:	PUNCT
fnp-2955	4	21	biswa	biswa	PROPN
fnp-2955	4	22	ramani	ramani	PROPN
fnp-2955	4	23	published	publish	VERB
fnp-2955	4	24	:	:	PUNCT
fnp-2955	4	25	08	08	NUM
fnp-2955	4	26	october	october	PROPN
fnp-2955	4	27	2020	2020	NUM
fnp-2955	5	1	https://doi.org/10.17879/freeneuropathology-2020-2955	https://doi.org/10.17879/freeneuropathology-2020-2955	VERB
fnp-2955	5	2	additional	additional	ADJ
fnp-2955	5	3	resources	resource	NOUN
fnp-2955	5	4	and	and	CCONJ
fnp-2955	5	5	electronic	electronic	ADJ
fnp-2955	5	6	supplementary	supplementary	ADJ
fnp-2955	5	7	material	material	NOUN
fnp-2955	5	8	:	:	PUNCT
fnp-2955	5	9	supplementary	supplementary	ADJ
fnp-2955	5	10	material	material	NOUN
fnp-2955	5	11	(	(	PUNCT
fnp-2955	5	12	zip	zip	NOUN
fnp-2955	5	13	)	)	PUNCT
fnp-2955	5	14	keywords	keyword	NOUN
fnp-2955	5	15	:	:	PUNCT
fnp-2955	5	16	extracellular	extracellular	ADJ
fnp-2955	5	17	matrix	matrix	NOUN
fnp-2955	5	18	,	,	PUNCT
fnp-2955	5	19	cell	cell	NOUN
fnp-2955	5	20	adhesion	adhesion	NOUN
fnp-2955	5	21	,	,	PUNCT
fnp-2955	5	22	clusterin	clusterin	NOUN
fnp-2955	5	23	,	,	PUNCT
fnp-2955	5	24	cerebral	cerebral	ADJ
fnp-2955	5	25	amyloid	amyloid	NOUN
fnp-2955	5	26	angiopathy	angiopathy	NOUN
fnp-2955	5	27	,	,	PUNCT
fnp-2955	5	28	caa	caa	NOUN
fnp-2955	5	29	,	,	PUNCT
fnp-2955	5	30	white	white	ADJ
fnp-2955	5	31	matter	matter	NOUN
fnp-2955	5	32	,	,	PUNCT
fnp-2955	5	33	proteomics	proteomic	NOUN
fnp-2955	5	34	abstract	abstract	ADJ
fnp-2955	5	35	aims	aim	NOUN
fnp-2955	5	36	:	:	PUNCT
fnp-2955	6	1	cerebral	cerebral	ADJ
fnp-2955	6	2	amyloid	amyloid	NOUN
fnp-2955	6	3	angiopathy	angiopathy	ADJ
fnp-2955	6	4	(	(	PUNCT
fnp-2955	6	5	caa	caa	NOUN
fnp-2955	6	6	)	)	PUNCT
fnp-2955	6	7	is	be	AUX
fnp-2955	6	8	the	the	DET
fnp-2955	6	9	accumulation	accumulation	NOUN
fnp-2955	6	10	of	of	ADP
fnp-2955	6	11	amyloid	amyloid	NOUN
fnp-2955	6	12	beta	beta	NOUN
fnp-2955	6	13	(	(	PUNCT
fnp-2955	6	14	aβ	aβ	NOUN
fnp-2955	6	15	)	)	PUNCT
fnp-2955	6	16	in	in	ADP
fnp-2955	6	17	the	the	DET
fnp-2955	6	18	walls	wall	NOUN
fnp-2955	6	19	of	of	ADP
fnp-2955	6	20	cerebral	cerebral	ADJ
fnp-2955	6	21	arterioles	arteriole	NOUN
fnp-2955	6	22	,	,	PUNCT
fnp-2955	6	23	arteries	artery	NOUN
fnp-2955	6	24	and	and	CCONJ
fnp-2955	6	25	capillaries	capillary	NOUN
fnp-2955	6	26	.	.	PUNCT
fnp-2955	7	1	changes	change	NOUN
fnp-2955	7	2	in	in	ADP
fnp-2955	7	3	the	the	DET
fnp-2955	7	4	white	white	ADJ
fnp-2955	7	5	matter	matter	NOUN
fnp-2955	7	6	in	in	ADP
fnp-2955	7	7	caa	caa	NOUN
fnp-2955	7	8	are	be	AUX
fnp-2955	7	9	observed	observe	VERB
fnp-2955	7	10	as	as	ADP
fnp-2955	7	11	hyperintensities	hyperintensitie	NOUN
fnp-2955	7	12	and	and	CCONJ
fnp-2955	7	13	dilated	dilate	VERB
fnp-2955	7	14	perivascular	perivascular	ADJ
fnp-2955	7	15	spaces	space	NOUN
fnp-2955	7	16	on	on	ADP
fnp-2955	7	17	mri	mri	NOUN
fnp-2955	7	18	suggesting	suggest	VERB
fnp-2955	7	19	impairment	impairment	NOUN
fnp-2955	7	20	of	of	ADP
fnp-2955	7	21	fluid	fluid	ADJ
fnp-2955	7	22	drainage	drainage	NOUN
fnp-2955	7	23	but	but	CCONJ
fnp-2955	7	24	the	the	DET
fnp-2955	7	25	pathophysiology	pathophysiology	NOUN
fnp-2955	7	26	behind	behind	ADP
fnp-2955	7	27	these	these	DET
fnp-2955	7	28	changes	change	NOUN
fnp-2955	7	29	is	be	AUX
fnp-2955	7	30	poorly	poorly	ADV
fnp-2955	7	31	understood	understand	VERB
fnp-2955	7	32	.	.	PUNCT
fnp-2955	8	1	we	we	PRON
fnp-2955	8	2	tested	test	VERB
fnp-2955	8	3	the	the	DET
fnp-2955	8	4	hypothesis	hypothesis	NOUN
fnp-2955	8	5	that	that	PRON
fnp-2955	8	6	proteins	protein	NOUN
fnp-2955	8	7	associated	associate	VERB
fnp-2955	8	8	with	with	ADP
fnp-2955	8	9	clearance	clearance	NOUN
fnp-2955	8	10	of	of	ADP
fnp-2955	8	11	aβ	aβ	NOUN
fnp-2955	8	12	peptides	peptide	NOUN
fnp-2955	8	13	are	be	AUX
fnp-2955	8	14	upregulated	upregulate	VERB
fnp-2955	8	15	in	in	ADP
fnp-2955	8	16	the	the	DET
fnp-2955	8	17	white	white	ADJ
fnp-2955	8	18	matter	matter	NOUN
fnp-2955	8	19	in	in	ADP
fnp-2955	8	20	cases	case	NOUN
fnp-2955	8	21	of	of	ADP
fnp-2955	8	22	caa	caa	NOUN
fnp-2955	8	23	.	.	PUNCT
fnp-2955	9	1	methods	method	NOUN
fnp-2955	9	2	:	:	PUNCT
fnp-2955	9	3	in	in	ADP
fnp-2955	9	4	this	this	DET
fnp-2955	9	5	study	study	NOUN
fnp-2955	9	6	,	,	PUNCT
fnp-2955	9	7	we	we	PRON
fnp-2955	9	8	compare	compare	VERB
fnp-2955	9	9	the	the	DET
fnp-2955	9	10	quantitative	quantitative	ADJ
fnp-2955	9	11	proteomic	proteomic	NOUN
fnp-2955	9	12	profile	profile	NOUN
fnp-2955	9	13	of	of	ADP
fnp-2955	9	14	white	white	ADJ
fnp-2955	9	15	matter	matter	NOUN
fnp-2955	9	16	from	from	ADP
fnp-2955	9	17	post	post	ADJ
fnp-2955	9	18	-	-	ADJ
fnp-2955	9	19	mortem	mortem	ADJ
fnp-2955	9	20	brains	brain	NOUN
fnp-2955	9	21	of	of	ADP
fnp-2955	9	22	patients	patient	NOUN
fnp-2955	9	23	with	with	ADP
fnp-2955	9	24	caa	caa	NOUN
fnp-2955	9	25	and	and	CCONJ
fnp-2955	9	26	age	age	NOUN
fnp-2955	9	27	-	-	PUNCT
fnp-2955	9	28	matched	match	VERB
fnp-2955	9	29	controls	control	NOUN
fnp-2955	9	30	in	in	ADP
fnp-2955	9	31	order	order	NOUN
fnp-2955	9	32	to	to	PART
fnp-2955	9	33	gain	gain	VERB
fnp-2955	9	34	insight	insight	NOUN
fnp-2955	9	35	into	into	ADP
fnp-2955	9	36	the	the	DET
fnp-2955	9	37	cellular	cellular	ADJ
fnp-2955	9	38	processes	process	NOUN
fnp-2955	9	39	and	and	CCONJ
fnp-2955	9	40	key	key	ADJ
fnp-2955	9	41	molecules	molecule	NOUN
fnp-2955	9	42	involved	involve	VERB
fnp-2955	9	43	in	in	ADP
fnp-2955	9	44	the	the	DET
fnp-2955	9	45	pathophysiology	pathophysiology	NOUN
fnp-2955	9	46	of	of	ADP
fnp-2955	9	47	caa	caa	NOUN
fnp-2955	9	48	.	.	PUNCT
fnp-2955	10	1	results	result	NOUN
fnp-2955	10	2	:	:	PUNCT
fnp-2955	10	3	our	our	PRON
fnp-2955	10	4	proteomic	proteomic	ADJ
fnp-2955	10	5	analysis	analysis	NOUN
fnp-2955	10	6	resulted	result	VERB
fnp-2955	10	7	in	in	ADP
fnp-2955	10	8	the	the	DET
fnp-2955	10	9	profiling	profiling	NOUN
fnp-2955	10	10	of	of	ADP
fnp-2955	10	11	3,734	3,734	NUM
fnp-2955	10	12	proteins	protein	NOUN
fnp-2955	10	13	(	(	PUNCT
fnp-2955	10	14	peptide	peptide	NOUN
fnp-2955	10	15	fdr	fdr	PROPN
fnp-2955	10	16	p<0.05	p<0.05	PROPN
fnp-2955	10	17	)	)	PUNCT
fnp-2955	10	18	.	.	PUNCT
fnp-2955	11	1	of	of	ADP
fnp-2955	11	2	these	these	PRON
fnp-2955	11	3	,	,	PUNCT
fnp-2955	11	4	189	189	NUM
fnp-2955	11	5	were	be	AUX
fnp-2955	11	6	differentially	differentially	ADV
fnp-2955	11	7	expressed	express	VERB
fnp-2955	11	8	in	in	ADP
fnp-2955	11	9	caa	caa	NOUN
fnp-2955	11	10	vs.	vs.	ADP
fnp-2955	11	11	control	control	NOUN
fnp-2955	11	12	.	.	PUNCT
fnp-2955	12	1	bioinformatics	bioinformatic	NOUN
fnp-2955	12	2	analysis	analysis	NOUN
fnp-2955	12	3	of	of	ADP
fnp-2955	12	4	these	these	DET
fnp-2955	12	5	proteins	protein	NOUN
fnp-2955	12	6	showed	show	VERB
fnp-2955	12	7	significant	significant	ADJ
fnp-2955	12	8	enrichment	enrichment	NOUN
fnp-2955	12	9	of	of	ADP
fnp-2955	12	10	proteins	protein	NOUN
fnp-2955	12	11	related	relate	VERB
fnp-2955	12	12	to	to	ADP
fnp-2955	12	13	cell	cell	NOUN
fnp-2955	12	14	adhesion	adhesion	NOUN
fnp-2955	12	15	|	|	NOUN
fnp-2955	12	16	cell	cell	NOUN
fnp-2955	12	17	-	-	PUNCT
fnp-2955	12	18	matrix	matrix	NOUN
fnp-2955	12	19	interaction	interaction	NOUN
fnp-2955	12	20	,	,	PUNCT
fnp-2955	12	21	mitochondrial	mitochondrial	ADJ
fnp-2955	12	22	dysfunction	dysfunction	NOUN
fnp-2955	12	23	and	and	CCONJ
fnp-2955	12	24	hypoxia	hypoxia	NOUN
fnp-2955	12	25	.	.	PUNCT
fnp-2955	12	26	upregulated	upregulated	ADJ
fnp-2955	12	27	proteins	protein	NOUN
fnp-2955	12	28	in	in	ADP
fnp-2955	12	29	caa	caa	NOUN
fnp-2955	12	30	included	include	VERB
fnp-2955	12	31	emilin2	emilin2	NOUN
fnp-2955	12	32	,	,	PUNCT
fnp-2955	12	33	col4a2	col4a2	NOUN
fnp-2955	12	34	,	,	PUNCT
fnp-2955	12	35	tln1	tln1	PROPN
fnp-2955	12	36	,	,	PUNCT
fnp-2955	12	37	clu	clu	PROPN
fnp-2955	12	38	,	,	PUNCT
fnp-2955	12	39	hspg2	hspg2	PROPN
fnp-2955	12	40	.	.	PUNCT
fnp-2955	13	1	downregulated	downregulate	VERB
fnp-2955	13	2	proteins	protein	NOUN
fnp-2955	13	3	included	include	VERB
fnp-2955	13	4	dsp	dsp	NOUN
fnp-2955	13	5	,	,	PUNCT
fnp-2955	13	6	ide	ide	NOUN
fnp-2955	13	7	,	,	PUNCT
fnp-2955	13	8	hbg1	hbg1	PROPN
fnp-2955	13	9	.	.	PUNCT
fnp-2955	14	1	conclusions	conclusion	NOUN
fnp-2955	14	2	:	:	PUNCT
fnp-2955	14	3	the	the	DET
fnp-2955	14	4	present	present	ADJ
fnp-2955	14	5	study	study	NOUN
fnp-2955	14	6	reports	report	VERB
fnp-2955	14	7	an	an	DET
fnp-2955	14	8	in	in	ADP
fnp-2955	14	9	-	-	PUNCT
fnp-2955	14	10	depth	depth	NOUN
fnp-2955	14	11	quantitative	quantitative	ADJ
fnp-2955	14	12	proteomic	proteomic	NOUN
fnp-2955	14	13	profiling	profiling	NOUN
fnp-2955	14	14	of	of	ADP
fnp-2955	14	15	white	white	ADJ
fnp-2955	14	16	matter	matter	NOUN
fnp-2955	14	17	from	from	ADP
fnp-2955	14	18	patients	patient	NOUN
fnp-2955	14	19	with	with	ADP
fnp-2955	14	20	caa	caa	NOUN
fnp-2955	14	21	,	,	PUNCT
fnp-2955	14	22	highlighting	highlight	VERB
fnp-2955	14	23	extracellular	extracellular	ADJ
fnp-2955	14	24	matrix	matrix	NOUN
fnp-2955	14	25	proteins	protein	NOUN
fnp-2955	14	26	and	and	CCONJ
fnp-2955	14	27	clusterin	clusterin	NOUN
fnp-2955	14	28	as	as	ADP
fnp-2955	14	29	key	key	ADJ
fnp-2955	14	30	molecules	molecule	NOUN
fnp-2955	14	31	in	in	ADP
fnp-2955	14	32	the	the	DET
fnp-2955	14	33	pathophysiology	pathophysiology	NOUN
fnp-2955	14	34	of	of	ADP
fnp-2955	14	35	white	white	ADJ
fnp-2955	14	36	matter	matter	NOUN
fnp-2955	14	37	changes	change	NOUN
fnp-2955	14	38	in	in	ADP
fnp-2955	14	39	cases	case	NOUN
fnp-2955	14	40	of	of	ADP
fnp-2955	14	41	caa	caa	NOUN
fnp-2955	14	42	.	.	PUNCT
fnp-2955	15	1	abbreviations	abbreviation	NOUN
fnp-2955	15	2	caa	caa	PROPN
fnp-2955	15	3	cerebral	cerebral	ADJ
fnp-2955	15	4	amyloid	amyloid	NOUN
fnp-2955	15	5	angiopathy	angiopathy	NOUN
fnp-2955	15	6	,	,	PUNCT
fnp-2955	15	7	wmh	wmh	NOUN
fnp-2955	15	8	white	white	ADJ
fnp-2955	15	9	matter	matter	NOUN
fnp-2955	15	10	hyperintensities	hyperintensitie	NOUN
fnp-2955	15	11	,	,	PUNCT
fnp-2955	15	12	ipa	ipa	PROPN
fnp-2955	15	13	ingenuity	ingenuity	NOUN
fnp-2955	15	14	pathway	pathway	NOUN
fnp-2955	15	15	analysis	analysis	NOUN
fnp-2955	15	16	,	,	PUNCT
fnp-2955	15	17	col4a2	col4a2	PROPN
fnp-2955	15	18	collagen	collagen	NOUN
fnp-2955	15	19	iv	iv	NUM
fnp-2955	15	20	alpha	alpha	NOUN
fnp-2955	15	21	2	2	NUM
fnp-2955	15	22	,	,	PUNCT
fnp-2955	15	23	hspg2	hspg2	VERB
fnp-2955	16	1	heparan	heparan	ADJ
fnp-2955	16	2	sulfate	sulfate	NOUN
fnp-2955	16	3	proteoglycan	proteoglycan	NOUN
fnp-2955	16	4	2	2	NUM
fnp-2955	16	5	,	,	PUNCT
fnp-2955	16	6	emilin2	emilin2	VERB
fnp-2955	16	7	emi	emi	NOUN
fnp-2955	16	8	domain	domain	NOUN
fnp-2955	16	9	endowed	endow	VERB
fnp-2955	16	10	,	,	PUNCT
fnp-2955	16	11	tln1	tln1	NOUN
fnp-2955	16	12	talin1	talin1	PROPN
fnp-2955	16	13	,	,	PUNCT
fnp-2955	16	14	clu	clu	PROPN
fnp-2955	16	15	clusterin	clusterin	NOUN
fnp-2955	16	16	,	,	PUNCT
fnp-2955	16	17	ide	ide	ADJ
fnp-2955	16	18	insulin	insulin	NOUN
fnp-2955	16	19	degrading	degrade	VERB
fnp-2955	16	20	enzyme	enzyme	NOUN
fnp-2955	16	21	,	,	PUNCT
fnp-2955	16	22	dsp	dsp	NOUN
fnp-2955	16	23	desmoplakin	desmoplakin	NOUN
fnp-2955	16	24	,	,	PUNCT
fnp-2955	16	25	ipad	ipad	NOUN
fnp-2955	16	26	intramural	intramural	ADJ
fnp-2955	16	27	periarterial	periarterial	ADJ
fnp-2955	16	28	drainage	drainage	NOUN
fnp-2955	16	29	.	.	PUNCT
fnp-2955	17	1	introduction	introduction	NOUN
fnp-2955	17	2	cerebral	cerebral	ADJ
fnp-2955	17	3	amyloid	amyloid	NOUN
fnp-2955	17	4	angiopathy	angiopathy	ADJ
fnp-2955	17	5	(	(	PUNCT
fnp-2955	17	6	caa	caa	NOUN
fnp-2955	17	7	)	)	PUNCT
fnp-2955	17	8	is	be	AUX
fnp-2955	17	9	characterized	characterize	VERB
fnp-2955	17	10	by	by	ADP
fnp-2955	17	11	the	the	DET
fnp-2955	17	12	deposition	deposition	NOUN
fnp-2955	17	13	of	of	ADP
fnp-2955	17	14	amyloid	amyloid	NOUN
fnp-2955	17	15	proteins	protein	NOUN
fnp-2955	17	16	including	include	VERB
fnp-2955	17	17	amyloid	amyloid	NOUN
fnp-2955	17	18	beta	beta	NOUN
fnp-2955	17	19	(	(	PUNCT
fnp-2955	17	20	aβ	aβ	NOUN
fnp-2955	17	21	)	)	PUNCT
fnp-2955	17	22	,	,	PUNCT
fnp-2955	17	23	cystatin	cystatin	PROPN
fnp-2955	17	24	c	c	NOUN
fnp-2955	17	25	,	,	PUNCT
fnp-2955	17	26	prion	prion	NOUN
fnp-2955	17	27	protein	protein	NOUN
fnp-2955	17	28	,	,	PUNCT
fnp-2955	17	29	abri	abri	PROPN
fnp-2955	17	30	/	/	SYM
fnp-2955	17	31	adan	adan	PROPN
fnp-2955	17	32	,	,	PUNCT
fnp-2955	17	33	transthyretin	transthyretin	PROPN
fnp-2955	17	34	,	,	PUNCT
fnp-2955	17	35	gelsolin	gelsolin	NOUN
fnp-2955	17	36	and	and	CCONJ
fnp-2955	17	37	immunoglobulin	immunoglobulin	NOUN
fnp-2955	17	38	light	light	NOUN
fnp-2955	17	39	chain	chain	NOUN
fnp-2955	17	40	amyloid	amyloid	NOUN
fnp-2955	17	41	(	(	PUNCT
fnp-2955	17	42	1	1	NUM
fnp-2955	17	43	)	)	PUNCT
fnp-2955	17	44	in	in	ADP
fnp-2955	17	45	the	the	DET
fnp-2955	17	46	walls	wall	NOUN
fnp-2955	17	47	of	of	ADP
fnp-2955	17	48	leptomenigeal	leptomenigeal	ADJ
fnp-2955	17	49	arteries	artery	NOUN
fnp-2955	17	50	and	and	CCONJ
fnp-2955	17	51	cortical	cortical	ADJ
fnp-2955	17	52	arterioles	arteriole	NOUN
fnp-2955	17	53	(	(	PUNCT
fnp-2955	17	54	caa	caa	NOUN
fnp-2955	17	55	-	-	PUNCT
fnp-2955	17	56	type	type	NOUN
fnp-2955	17	57	2	2	NUM
fnp-2955	17	58	)	)	PUNCT
fnp-2955	17	59	(	(	PUNCT
fnp-2955	17	60	2	2	NUM
fnp-2955	17	61	)	)	PUNCT
fnp-2955	17	62	and	and	CCONJ
fnp-2955	17	63	in	in	ADP
fnp-2955	17	64	the	the	DET
fnp-2955	17	65	walls	wall	NOUN
fnp-2955	17	66	of	of	ADP
fnp-2955	17	67	arteries	artery	NOUN
fnp-2955	17	68	or	or	CCONJ
fnp-2955	17	69	capillaries	capillary	NOUN
fnp-2955	17	70	(	(	PUNCT
fnp-2955	17	71	caa	caa	NOUN
fnp-2955	17	72	-	-	PUNCT
fnp-2955	17	73	type	type	NOUN
fnp-2955	17	74	1	1	NUM
fnp-2955	17	75	)	)	PUNCT
fnp-2955	17	76	,	,	PUNCT
fnp-2955	17	77	but	but	CCONJ
fnp-2955	17	78	rarely	rarely	ADV
fnp-2955	17	79	in	in	ADP
fnp-2955	17	80	the	the	DET
fnp-2955	17	81	walls	wall	NOUN
fnp-2955	17	82	of	of	ADP
fnp-2955	17	83	venules	venule	NOUN
fnp-2955	17	84	(	(	PUNCT
fnp-2955	17	85	1	1	NUM
fnp-2955	17	86	-	-	SYM
fnp-2955	17	87	3	3	NUM
fnp-2955	17	88	)	)	PUNCT
fnp-2955	17	89	.	.	PUNCT
fnp-2955	18	1	sporadic	sporadic	ADJ
fnp-2955	18	2	caa	caa	NOUN
fnp-2955	18	3	is	be	AUX
fnp-2955	18	4	a	a	DET
fnp-2955	18	5	common	common	ADJ
fnp-2955	18	6	feature	feature	NOUN
fnp-2955	18	7	of	of	ADP
fnp-2955	18	8	alzheimer	alzheimer	PROPN
fnp-2955	18	9	’s	’s	PART
fnp-2955	18	10	disease	disease	NOUN
fnp-2955	18	11	(	(	PUNCT
fnp-2955	18	12	1	1	NUM
fnp-2955	18	13	-	-	SYM
fnp-2955	18	14	3	3	NUM
fnp-2955	18	15	)	)	PUNCT
fnp-2955	18	16	and	and	CCONJ
fnp-2955	18	17	reflects	reflect	VERB
fnp-2955	18	18	the	the	DET
fnp-2955	18	19	failure	failure	NOUN
fnp-2955	18	20	of	of	ADP
fnp-2955	18	21	clearance	clearance	NOUN
fnp-2955	18	22	of	of	ADP
fnp-2955	18	23	proteins	protein	NOUN
fnp-2955	18	24	and	and	CCONJ
fnp-2955	18	25	interstitial	interstitial	ADJ
fnp-2955	18	26	fluid	fluid	NOUN
fnp-2955	18	27	from	from	ADP
fnp-2955	18	28	the	the	DET
fnp-2955	18	29	ageing	age	VERB
fnp-2955	18	30	brain	brain	NOUN
fnp-2955	18	31	(	(	PUNCT
fnp-2955	18	32	4	4	NUM
fnp-2955	18	33	,	,	PUNCT
fnp-2955	18	34	5	5	NUM
fnp-2955	18	35	)	)	PUNCT
fnp-2955	18	36	.	.	PUNCT
fnp-2955	19	1	although	although	SCONJ
fnp-2955	19	2	caa	caa	NOUN
fnp-2955	19	3	is	be	AUX
fnp-2955	19	4	uncommon	uncommon	ADJ
fnp-2955	19	5	in	in	ADP
fnp-2955	19	6	the	the	DET
fnp-2955	19	7	white	white	ADJ
fnp-2955	19	8	matter	matter	NOUN
fnp-2955	19	9	,	,	PUNCT
fnp-2955	19	10	(	(	PUNCT
fnp-2955	19	11	6	6	X
fnp-2955	19	12	)	)	PUNCT
fnp-2955	19	13	there	there	PRON
fnp-2955	19	14	are	be	VERB
fnp-2955	19	15	radiological	radiological	ADJ
fnp-2955	19	16	features	feature	NOUN
fnp-2955	19	17	in	in	ADP
fnp-2955	19	18	the	the	DET
fnp-2955	19	19	white	white	ADJ
fnp-2955	19	20	matter	matter	NOUN
fnp-2955	19	21	in	in	ADP
fnp-2955	19	22	cases	case	NOUN
fnp-2955	19	23	of	of	ADP
fnp-2955	19	24	caa	caa	NOUN
fnp-2955	19	25	that	that	PRON
fnp-2955	19	26	include	include	VERB
fnp-2955	19	27	white	white	ADJ
fnp-2955	19	28	matter	matter	NOUN
fnp-2955	19	29	hyperintensities	hyperintensitie	NOUN
fnp-2955	19	30	(	(	PUNCT
fnp-2955	19	31	wmh	wmh	NOUN
fnp-2955	19	32	)	)	PUNCT
fnp-2955	19	33	and	and	CCONJ
fnp-2955	19	34	dilated	dilate	VERB
fnp-2955	19	35	perivascular	perivascular	ADJ
fnp-2955	19	36	spaces	space	NOUN
fnp-2955	19	37	(	(	PUNCT
fnp-2955	19	38	7	7	NUM
fnp-2955	19	39	,	,	PUNCT
fnp-2955	19	40	8)	8)	NUM
fnp-2955	19	41	.	.	PUNCT
fnp-2955	20	1	the	the	DET
fnp-2955	20	2	underlining	underlining	ADJ
fnp-2955	20	3	pathophysiology	pathophysiology	NOUN
fnp-2955	20	4	is	be	AUX
fnp-2955	20	5	poorly	poorly	ADV
fnp-2955	20	6	understood	understand	VERB
fnp-2955	20	7	,	,	PUNCT
fnp-2955	20	8	but	but	CCONJ
fnp-2955	20	9	the	the	DET
fnp-2955	20	10	wmh	wmh	NOUN
fnp-2955	20	11	are	be	AUX
fnp-2955	20	12	associated	associate	VERB
fnp-2955	20	13	with	with	ADP
fnp-2955	20	14	small	small	ADJ
fnp-2955	20	15	vessel	vessel	NOUN
fnp-2955	20	16	disease	disease	NOUN
fnp-2955	20	17	(	(	PUNCT
fnp-2955	20	18	9	9	NUM
fnp-2955	20	19	)	)	PUNCT
fnp-2955	20	20	.	.	PUNCT
fnp-2955	21	1	in	in	ADP
fnp-2955	21	2	addition	addition	NOUN
fnp-2955	21	3	to	to	ADP
fnp-2955	21	4	damage	damage	NOUN
fnp-2955	21	5	to	to	ADP
fnp-2955	21	6	nerve	nerve	NOUN
fnp-2955	21	7	fibres	fibre	NOUN
fnp-2955	21	8	particularly	particularly	ADV
fnp-2955	21	9	in	in	ADP
fnp-2955	21	10	the	the	DET
fnp-2955	21	11	deep	deep	ADJ
fnp-2955	21	12	white	white	ADJ
fnp-2955	21	13	matter	matter	NOUN
fnp-2955	21	14	,	,	PUNCT
fnp-2955	21	15	the	the	DET
fnp-2955	21	16	wmh	wmh	NOUN
fnp-2955	21	17	suggest	suggest	VERB
fnp-2955	21	18	that	that	SCONJ
fnp-2955	21	19	there	there	PRON
fnp-2955	21	20	is	be	VERB
fnp-2955	21	21	an	an	DET
fnp-2955	21	22	increase	increase	NOUN
fnp-2955	21	23	in	in	ADP
fnp-2955	21	24	the	the	DET
fnp-2955	21	25	volume	volume	NOUN
fnp-2955	21	26	of	of	ADP
fnp-2955	21	27	interstitial	interstitial	ADJ
fnp-2955	21	28	fluid	fluid	NOUN
fnp-2955	21	29	(	(	PUNCT
fnp-2955	21	30	isf	isf	NOUN
fnp-2955	21	31	)	)	PUNCT
fnp-2955	21	32	in	in	ADP
fnp-2955	21	33	the	the	DET
fnp-2955	21	34	affected	affect	VERB
fnp-2955	21	35	white	white	ADJ
fnp-2955	21	36	matter	matter	NOUN
fnp-2955	21	37	.	.	PUNCT
fnp-2955	22	1	pathologically	pathologically	ADV
fnp-2955	22	2	,	,	PUNCT
fnp-2955	22	3	wmh	wmh	NOUN
fnp-2955	22	4	are	be	AUX
fnp-2955	22	5	characterised	characterise	VERB
fnp-2955	22	6	by	by	ADP
fnp-2955	22	7	pallor	pallor	NOUN
fnp-2955	22	8	of	of	ADP
fnp-2955	22	9	myelin	myelin	NOUN
fnp-2955	22	10	staining	staining	NOUN
fnp-2955	22	11	in	in	ADP
fnp-2955	22	12	the	the	DET
fnp-2955	22	13	affected	affect	VERB
fnp-2955	22	14	white	white	ADJ
fnp-2955	22	15	matter	matter	NOUN
fnp-2955	22	16	with	with	ADP
fnp-2955	22	17	morphological	morphological	ADJ
fnp-2955	22	18	changes	change	NOUN
fnp-2955	22	19	in	in	ADP
fnp-2955	22	20	astrocytes	astrocyte	NOUN
fnp-2955	22	21	and	and	CCONJ
fnp-2955	22	22	axons	axon	NOUN
fnp-2955	22	23	and	and	CCONJ
fnp-2955	22	24	disruption	disruption	NOUN
fnp-2955	22	25	of	of	ADP
fnp-2955	22	26	the	the	DET
fnp-2955	22	27	distribution	distribution	NOUN
fnp-2955	22	28	of	of	ADP
fnp-2955	22	29	aquaporin	aquaporin	NOUN
fnp-2955	22	30	4	4	NUM
fnp-2955	22	31	in	in	ADP
fnp-2955	22	32	astrocyte	astrocyte	NOUN
fnp-2955	22	33	processes	process	NOUN
fnp-2955	22	34	(	(	PUNCT
fnp-2955	22	35	10	10	NUM
fnp-2955	22	36	)	)	PUNCT
fnp-2955	22	37	.	.	PUNCT
fnp-2955	23	1	imaging	image	VERB
fnp-2955	23	2	studies	study	NOUN
fnp-2955	23	3	in	in	ADP
fnp-2955	23	4	the	the	DET
fnp-2955	23	5	early	early	ADJ
fnp-2955	23	6	stages	stage	NOUN
fnp-2955	23	7	of	of	ADP
fnp-2955	23	8	wmh	wmh	NOUN
fnp-2955	23	9	suggest	suggest	VERB
fnp-2955	23	10	that	that	SCONJ
fnp-2955	23	11	the	the	DET
fnp-2955	23	12	lesions	lesion	NOUN
fnp-2955	23	13	are	be	AUX
fnp-2955	23	14	due	due	ADJ
fnp-2955	23	15	to	to	PART
fnp-2955	23	16	altered	alter	VERB
fnp-2955	23	17	interstitial	interstitial	ADJ
fnp-2955	23	18	fluid	fluid	NOUN
fnp-2955	23	19	mobility	mobility	NOUN
fnp-2955	23	20	and	and	CCONJ
fnp-2955	23	21	water	water	NOUN
fnp-2955	23	22	content	content	NOUN
fnp-2955	23	23	that	that	PRON
fnp-2955	23	24	may	may	AUX
fnp-2955	23	25	be	be	AUX
fnp-2955	23	26	reversible	reversible	ADJ
fnp-2955	23	27	(	(	PUNCT
fnp-2955	23	28	11	11	NUM
fnp-2955	23	29	)	)	PUNCT
fnp-2955	23	30	.	.	PUNCT
fnp-2955	24	1	interstitial	interstitial	ADJ
fnp-2955	24	2	fluid	fluid	NOUN
fnp-2955	24	3	and	and	CCONJ
fnp-2955	24	4	aβ	aβ	PRON
fnp-2955	24	5	enter	enter	VERB
fnp-2955	24	6	the	the	DET
fnp-2955	24	7	basement	basement	NOUN
fnp-2955	24	8	membranes	membrane	NOUN
fnp-2955	24	9	of	of	ADP
fnp-2955	24	10	capillaries	capillary	NOUN
fnp-2955	24	11	and	and	CCONJ
fnp-2955	24	12	arteries	artery	NOUN
fnp-2955	24	13	to	to	PART
fnp-2955	24	14	be	be	AUX
fnp-2955	24	15	cleared	clear	VERB
fnp-2955	24	16	from	from	ADP
fnp-2955	24	17	the	the	DET
fnp-2955	24	18	brain	brain	NOUN
fnp-2955	24	19	along	along	ADP
fnp-2955	24	20	the	the	DET
fnp-2955	24	21	intramural	intramural	ADJ
fnp-2955	24	22	periarterial	periarterial	ADJ
fnp-2955	24	23	drainage	drainage	NOUN
fnp-2955	24	24	(	(	PUNCT
fnp-2955	24	25	ipad	ipad	NOUN
fnp-2955	24	26	)	)	PUNCT
fnp-2955	24	27	pathways	pathway	NOUN
fnp-2955	24	28	(	(	PUNCT
fnp-2955	24	29	12	12	NUM
fnp-2955	24	30	,	,	PUNCT
fnp-2955	24	31	13	13	NUM
fnp-2955	24	32	)	)	PUNCT
fnp-2955	24	33	.	.	PUNCT
fnp-2955	25	1	with	with	ADP
fnp-2955	25	2	increasing	increase	VERB
fnp-2955	25	3	age	age	NOUN
fnp-2955	25	4	,	,	PUNCT
fnp-2955	25	5	the	the	DET
fnp-2955	25	6	structure	structure	NOUN
fnp-2955	25	7	of	of	ADP
fnp-2955	25	8	basement	basement	NOUN
fnp-2955	25	9	membranes	membrane	NOUN
fnp-2955	25	10	changes	change	NOUN
fnp-2955	25	11	and	and	CCONJ
fnp-2955	25	12	aβ	aβ	NOUN
fnp-2955	25	13	accumulates	accumulate	VERB
fnp-2955	25	14	in	in	ADP
fnp-2955	25	15	the	the	DET
fnp-2955	25	16	walls	wall	NOUN
fnp-2955	25	17	of	of	ADP
fnp-2955	25	18	arteries	artery	NOUN
fnp-2955	25	19	as	as	ADP
fnp-2955	25	20	caa	caa	NOUN
fnp-2955	25	21	(	(	PUNCT
fnp-2955	25	22	14	14	NUM
fnp-2955	25	23	-	-	SYM
fnp-2955	25	24	16	16	NUM
fnp-2955	25	25	)	)	PUNCT
fnp-2955	25	26	.	.	PUNCT
fnp-2955	26	1	our	our	PRON
fnp-2955	26	2	proteomic	proteomic	ADJ
fnp-2955	26	3	studies	study	NOUN
fnp-2955	26	4	performed	perform	VERB
fnp-2955	26	5	on	on	ADP
fnp-2955	26	6	leptomeningeal	leptomeningeal	NOUN
fnp-2955	26	7	arteries	artery	NOUN
fnp-2955	26	8	from	from	ADP
fnp-2955	26	9	brains	brain	NOUN
fnp-2955	26	10	with	with	ADP
fnp-2955	26	11	caa	caa	NOUN
fnp-2955	26	12	demonstrated	demonstrate	VERB
fnp-2955	26	13	an	an	DET
fnp-2955	26	14	upregulation	upregulation	NOUN
fnp-2955	26	15	of	of	ADP
fnp-2955	26	16	clusterin	clusterin	NOUN
fnp-2955	26	17	(	(	PUNCT
fnp-2955	26	18	apolipoprotein	apolipoprotein	VERB
fnp-2955	26	19	j	j	PROPN
fnp-2955	26	20	)	)	PUNCT
fnp-2955	26	21	and	and	CCONJ
fnp-2955	26	22	tissue	tissue	NOUN
fnp-2955	26	23	inhibitors	inhibitor	NOUN
fnp-2955	26	24	of	of	ADP
fnp-2955	26	25	metalloproteinases	metalloproteinase	NOUN
fnp-2955	26	26	3	3	NUM
fnp-2955	26	27	(	(	PUNCT
fnp-2955	26	28	timp3	timp3	NOUN
fnp-2955	26	29	)	)	PUNCT
fnp-2955	26	30	(	(	PUNCT
fnp-2955	26	31	17	17	NUM
fnp-2955	26	32	)	)	PUNCT
fnp-2955	26	33	.	.	PUNCT
fnp-2955	27	1	the	the	DET
fnp-2955	27	2	aim	aim	NOUN
fnp-2955	27	3	of	of	ADP
fnp-2955	27	4	the	the	DET
fnp-2955	27	5	present	present	ADJ
fnp-2955	27	6	study	study	NOUN
fnp-2955	27	7	was	be	AUX
fnp-2955	27	8	to	to	PART
fnp-2955	27	9	compare	compare	VERB
fnp-2955	27	10	the	the	DET
fnp-2955	27	11	quantitative	quantitative	ADJ
fnp-2955	27	12	proteomic	proteomic	NOUN
fnp-2955	27	13	profile	profile	NOUN
fnp-2955	27	14	of	of	ADP
fnp-2955	27	15	white	white	ADJ
fnp-2955	27	16	matter	matter	NOUN
fnp-2955	27	17	from	from	ADP
fnp-2955	27	18	patients	patient	NOUN
fnp-2955	27	19	with	with	ADP
fnp-2955	27	20	caa	caa	NOUN
fnp-2955	27	21	to	to	ADP
fnp-2955	27	22	the	the	DET
fnp-2955	27	23	corresponding	corresponding	ADJ
fnp-2955	27	24	brain	brain	NOUN
fnp-2955	27	25	region	region	NOUN
fnp-2955	27	26	of	of	ADP
fnp-2955	27	27	age	age	NOUN
fnp-2955	27	28	-	-	PUNCT
fnp-2955	27	29	matched	match	VERB
fnp-2955	27	30	controls	control	NOUN
fnp-2955	27	31	in	in	ADP
fnp-2955	27	32	order	order	NOUN
fnp-2955	27	33	to	to	PART
fnp-2955	27	34	gain	gain	VERB
fnp-2955	27	35	insight	insight	NOUN
fnp-2955	27	36	in	in	ADP
fnp-2955	27	37	the	the	DET
fnp-2955	27	38	pathophysiology	pathophysiology	NOUN
fnp-2955	27	39	of	of	ADP
fnp-2955	27	40	white	white	ADJ
fnp-2955	27	41	matter	matter	NOUN
fnp-2955	27	42	changes	change	NOUN
fnp-2955	27	43	in	in	ADP
fnp-2955	27	44	caa	caa	NOUN
fnp-2955	27	45	and	and	CCONJ
fnp-2955	27	46	to	to	PART
fnp-2955	27	47	identify	identify	VERB
fnp-2955	27	48	novel	novel	ADJ
fnp-2955	27	49	therapeutic	therapeutic	ADJ
fnp-2955	27	50	targets	target	NOUN
fnp-2955	27	51	.	.	PUNCT
fnp-2955	28	1	an	an	DET
fnp-2955	28	2	overview	overview	NOUN
fnp-2955	28	3	of	of	ADP
fnp-2955	28	4	the	the	DET
fnp-2955	28	5	present	present	ADJ
fnp-2955	28	6	study	study	NOUN
fnp-2955	28	7	workflow	workflow	NOUN
fnp-2955	28	8	is	be	AUX
fnp-2955	28	9	presented	present	VERB
fnp-2955	28	10	in	in	ADP
fnp-2955	28	11	figure	figure	NOUN
fnp-2955	28	12	1	1	NUM
fnp-2955	28	13	.	.	PUNCT
fnp-2955	29	1	figure	figure	NOUN
fnp-2955	29	2	1	1	NUM
fnp-2955	29	3	:	:	PUNCT
fnp-2955	29	4	outline	outline	NOUN
fnp-2955	29	5	of	of	ADP
fnp-2955	29	6	experimental	experimental	ADJ
fnp-2955	29	7	workflow	workflow	NOUN
fnp-2955	29	8	.	.	PUNCT
fnp-2955	30	1	labelled	label	VERB
fnp-2955	30	2	peptides	peptide	NOUN
fnp-2955	30	3	were	be	AUX
fnp-2955	30	4	analysed	analyse	VERB
fnp-2955	30	5	using	use	VERB
fnp-2955	30	6	two	two	NUM
fnp-2955	30	7	-	-	PUNCT
fnp-2955	30	8	dimensional	dimensional	ADJ
fnp-2955	30	9	liquid	liquid	ADJ
fnp-2955	30	10	chromatography	chromatography	NOUN
fnp-2955	30	11	and	and	CCONJ
fnp-2955	30	12	tandem	tandem	NOUN
fnp-2955	30	13	mass	mass	PROPN
fnp-2955	30	14	spectrometry	spectrometry	NOUN
fnp-2955	30	15	.	.	PUNCT
fnp-2955	31	1	materials	material	NOUN
fnp-2955	31	2	and	and	CCONJ
fnp-2955	31	3	methods	method	NOUN
fnp-2955	31	4	tissue	tissue	NOUN
fnp-2955	31	5	samples	sample	NOUN
fnp-2955	31	6	fresh	fresh	ADJ
fnp-2955	31	7	frozen	frozen	ADJ
fnp-2955	31	8	white	white	ADJ
fnp-2955	31	9	matter	matter	NOUN
fnp-2955	31	10	from	from	ADP
fnp-2955	31	11	the	the	DET
fnp-2955	31	12	occipital	occipital	NOUN
fnp-2955	31	13	lobe	lobe	NOUN
fnp-2955	31	14	of	of	ADP
fnp-2955	31	15	severe	severe	ADJ
fnp-2955	31	16	caa	caa	NOUN
fnp-2955	31	17	cases	case	NOUN
fnp-2955	31	18	(	(	PUNCT
fnp-2955	31	19	n=6	n=6	NOUN
fnp-2955	31	20	)	)	PUNCT
fnp-2955	31	21	and	and	CCONJ
fnp-2955	31	22	non	non	ADJ
fnp-2955	31	23	-	-	ADJ
fnp-2955	31	24	demented	demented	ADJ
fnp-2955	31	25	aged	aged	ADJ
fnp-2955	31	26	matched	match	VERB
fnp-2955	31	27	controls	control	NOUN
fnp-2955	31	28	(	(	PUNCT
fnp-2955	31	29	n=4	n=4	NOUN
fnp-2955	31	30	)	)	PUNCT
fnp-2955	31	31	was	be	AUX
fnp-2955	31	32	supplied	supply	VERB
fnp-2955	31	33	by	by	ADP
fnp-2955	31	34	newcastle	newcastle	PROPN
fnp-2955	31	35	brain	brain	NOUN
fnp-2955	31	36	tissue	tissue	NOUN
fnp-2955	31	37	resource	resource	NOUN
fnp-2955	31	38	(	(	PUNCT
fnp-2955	31	39	ethics	ethic	NOUN
fnp-2955	31	40	rec	rec	X
fnp-2955	31	41	08	08	NUM
fnp-2955	31	42	/	/	SYM
fnp-2955	31	43	h0906/136	h0906/136	NOUN
fnp-2955	31	44	)	)	PUNCT
fnp-2955	31	45	(	(	PUNCT
fnp-2955	31	46	table	table	NOUN
fnp-2955	31	47	1	1	NUM
fnp-2955	31	48	)	)	PUNCT
fnp-2955	31	49	.	.	PUNCT
fnp-2955	32	1	all	all	DET
fnp-2955	32	2	cases	case	NOUN
fnp-2955	32	3	were	be	AUX
fnp-2955	32	4	diagnosed	diagnose	VERB
fnp-2955	32	5	according	accord	VERB
fnp-2955	32	6	to	to	ADP
fnp-2955	32	7	internationally	internationally	ADV
fnp-2955	32	8	-	-	PUNCT
fnp-2955	32	9	used	use	VERB
fnp-2955	32	10	criteria	criterion	NOUN
fnp-2955	32	11	including	include	VERB
fnp-2955	32	12	neuritic	neuritic	ADJ
fnp-2955	32	13	braak	braak	NOUN
fnp-2955	32	14	stages	stage	NOUN
fnp-2955	32	15	(	(	PUNCT
fnp-2955	32	16	18	18	NUM
fnp-2955	32	17	)	)	PUNCT
fnp-2955	32	18	,	,	PUNCT
fnp-2955	32	19	thal	thal	NOUN
fnp-2955	32	20	amyloid	amyloid	NOUN
fnp-2955	32	21	phases	phase	NOUN
fnp-2955	32	22	(	(	PUNCT
fnp-2955	32	23	19	19	NUM
fnp-2955	32	24	)	)	PUNCT
fnp-2955	32	25	,	,	PUNCT
fnp-2955	32	26	and	and	CCONJ
fnp-2955	32	27	cerad	cerad	PROPN
fnp-2955	32	28	scores	score	NOUN
fnp-2955	32	29	(	(	PUNCT
fnp-2955	32	30	20	20	NUM
fnp-2955	32	31	)	)	PUNCT
fnp-2955	32	32	(	(	PUNCT
fnp-2955	32	33	table	table	NOUN
fnp-2955	32	34	1	1	NUM
fnp-2955	32	35	)	)	PUNCT
fnp-2955	32	36	.	.	PUNCT
fnp-2955	33	1	table	table	NOUN
fnp-2955	33	2	1	1	NUM
fnp-2955	33	3	:	:	PUNCT
fnp-2955	33	4	header	header	NOUN
fnp-2955	33	5	table	table	NOUN
fnp-2955	33	6	1	1	NUM
fnp-2955	33	7	:	:	PUNCT
fnp-2955	33	8	demographics	demographic	NOUN
fnp-2955	33	9	of	of	ADP
fnp-2955	33	10	the	the	DET
fnp-2955	33	11	cases	case	NOUN
fnp-2955	33	12	used	use	VERB
fnp-2955	33	13	for	for	ADP
fnp-2955	33	14	this	this	DET
fnp-2955	33	15	study	study	NOUN
fnp-2955	33	16	.	.	PUNCT
fnp-2955	34	1	pm	pm	NOUN
fnp-2955	34	2	:	:	PUNCT
fnp-2955	34	3	post	post	ADJ
fnp-2955	34	4	-	-	ADJ
fnp-2955	34	5	mortem	mortem	ADJ
fnp-2955	34	6	.	.	PUNCT
fnp-2955	35	1	the	the	DET
fnp-2955	35	2	pm	pm	NOUN
fnp-2955	35	3	delay	delay	NOUN
fnp-2955	35	4	refers	refer	VERB
fnp-2955	35	5	to	to	ADP
fnp-2955	35	6	the	the	DET
fnp-2955	35	7	number	number	NOUN
fnp-2955	35	8	of	of	ADP
fnp-2955	35	9	hours	hour	NOUN
fnp-2955	35	10	post	post	ADJ
fnp-2955	35	11	-	-	ADJ
fnp-2955	35	12	mortem	mortem	ADJ
fnp-2955	35	13	until	until	SCONJ
fnp-2955	35	14	the	the	DET
fnp-2955	35	15	tissue	tissue	NOUN
fnp-2955	35	16	was	be	AUX
fnp-2955	35	17	dissected	dissect	VERB
fnp-2955	35	18	and	and	CCONJ
fnp-2955	35	19	frozen	frozen	ADJ
fnp-2955	35	20	.	.	PUNCT
fnp-2955	36	1	tissue	tissue	NOUN
fnp-2955	36	2	quantitative	quantitative	ADJ
fnp-2955	36	3	proteomics	proteomic	NOUN
fnp-2955	36	4	analysis	analysis	NOUN
fnp-2955	36	5	samples	sample	NOUN
fnp-2955	36	6	of	of	ADP
fnp-2955	36	7	1	1	NUM
fnp-2955	36	8	mg	mg	NOUN
fnp-2955	36	9	per	per	ADP
fnp-2955	36	10	case	case	NOUN
fnp-2955	36	11	were	be	AUX
fnp-2955	36	12	dissolved	dissolve	VERB
fnp-2955	36	13	in	in	ADP
fnp-2955	36	14	0.5	0.5	NUM
fnp-2955	36	15	m	m	NOUN
fnp-2955	36	16	triethylammonium	triethylammonium	NOUN
fnp-2955	36	17	bicarbonate	bicarbonate	NOUN
fnp-2955	36	18	in	in	ADP
fnp-2955	36	19	0.05	0.05	NUM
fnp-2955	36	20	%	%	NOUN
fnp-2955	36	21	sodium	sodium	NOUN
fnp-2955	36	22	dodecyl	dodecyl	NOUN
fnp-2955	36	23	sulphate	sulphate	NOUN
fnp-2955	36	24	.	.	PUNCT
fnp-2955	37	1	these	these	PRON
fnp-2955	37	2	were	be	AUX
fnp-2955	37	3	then	then	ADV
fnp-2955	37	4	subjected	subject	VERB
fnp-2955	37	5	to	to	ADP
fnp-2955	37	6	pulsed	pulsed	ADJ
fnp-2955	37	7	probe	probe	NOUN
fnp-2955	37	8	sonication	sonication	NOUN
fnp-2955	37	9	(	(	PUNCT
fnp-2955	37	10	misonix	misonix	PROPN
fnp-2955	37	11	,	,	PUNCT
fnp-2955	37	12	farmingdale	farmingdale	PROPN
fnp-2955	37	13	,	,	PUNCT
fnp-2955	37	14	ny	ny	PROPN
fnp-2955	37	15	,	,	PUNCT
fnp-2955	37	16	usa	usa	PROPN
fnp-2955	37	17	)	)	PUNCT
fnp-2955	37	18	and	and	CCONJ
fnp-2955	37	19	lysates	lysate	NOUN
fnp-2955	37	20	were	be	AUX
fnp-2955	37	21	centrifuged	centrifuge	VERB
fnp-2955	37	22	(	(	PUNCT
fnp-2955	37	23	16,000	16,000	NUM
fnp-2955	37	24	g	g	NOUN
fnp-2955	37	25	,	,	PUNCT
fnp-2955	37	26	10	10	NUM
fnp-2955	37	27	min	min	NOUN
fnp-2955	37	28	,	,	PUNCT
fnp-2955	37	29	4	4	NUM
fnp-2955	37	30	°	°	NOUN
fnp-2955	37	31	c	c	NOUN
fnp-2955	37	32	)	)	PUNCT
fnp-2955	37	33	.	.	PUNCT
fnp-2955	38	1	supernatants	supernatant	NOUN
fnp-2955	38	2	were	be	AUX
fnp-2955	38	3	measured	measure	VERB
fnp-2955	38	4	for	for	ADP
fnp-2955	38	5	protein	protein	NOUN
fnp-2955	38	6	content	content	NOUN
fnp-2955	38	7	using	use	VERB
fnp-2955	38	8	the	the	DET
fnp-2955	38	9	bicinchoninic	bicinchoninic	ADJ
fnp-2955	38	10	acid	acid	NOUN
fnp-2955	38	11	assay	assay	NOUN
fnp-2955	38	12	(	(	PUNCT
fnp-2955	38	13	pierce	pierce	PROPN
fnp-2955	38	14	bca	bca	PROPN
fnp-2955	38	15	protein	protein	NOUN
fnp-2955	38	16	assay	assay	PROPN
fnp-2955	38	17	kit	kit	PROPN
fnp-2955	38	18	,	,	PUNCT
fnp-2955	38	19	thermo	thermo	NOUN
fnp-2955	38	20	fisher	fisher	PROPN
fnp-2955	38	21	scientific	scientific	PROPN
fnp-2955	38	22	,	,	PUNCT
fnp-2955	38	23	waltham	waltham	PROPN
fnp-2955	38	24	,	,	PUNCT
fnp-2955	38	25	ma	ma	PROPN
fnp-2955	38	26	,	,	PUNCT
fnp-2955	38	27	us	us	PROPN
fnp-2955	38	28	)	)	PUNCT
fnp-2955	38	29	.	.	PUNCT
fnp-2955	39	1	100	100	NUM
fnp-2955	39	2	μg	μg	NOUN
fnp-2955	39	3	of	of	ADP
fnp-2955	39	4	protein	protein	NOUN
fnp-2955	39	5	was	be	AUX
fnp-2955	39	6	used	use	VERB
fnp-2955	39	7	per	per	ADP
fnp-2955	39	8	sample	sample	NOUN
fnp-2955	39	9	,	,	PUNCT
fnp-2955	39	10	adjusted	adjust	VERB
fnp-2955	39	11	to	to	ADP
fnp-2955	39	12	the	the	DET
fnp-2955	39	13	highest	high	ADJ
fnp-2955	39	14	volume	volume	NOUN
fnp-2955	39	15	.	.	PUNCT
fnp-2955	40	1	proteins	protein	NOUN
fnp-2955	40	2	were	be	AUX
fnp-2955	40	3	reduced	reduce	VERB
fnp-2955	40	4	with	with	ADP
fnp-2955	40	5	4μl	4μl	ADJ
fnp-2955	40	6	50	50	NUM
fnp-2955	40	7	mm	mm	NOUN
fnp-2955	40	8	tris(2	tris(2	NOUN
fnp-2955	40	9	-	-	PUNCT
fnp-2955	40	10	carboxyethyl)phosphine	carboxyethyl)phosphine	NOUN
fnp-2955	40	11	hydrochloride	hydrochloride	NOUN
fnp-2955	40	12	at	at	ADP
fnp-2955	40	13	60	60	NUM
fnp-2955	40	14	°	°	ADP
fnp-2955	40	15	c	c	NOUN
fnp-2955	40	16	for	for	ADP
fnp-2955	40	17	1	1	NUM
fnp-2955	40	18	hour	hour	NOUN
fnp-2955	40	19	and	and	CCONJ
fnp-2955	40	20	alkylated	alkylate	VERB
fnp-2955	40	21	using	use	VERB
fnp-2955	40	22	2	2	NUM
fnp-2955	40	23	μl	μl	ADP
fnp-2955	40	24	200	200	NUM
fnp-2955	40	25	mm	mm	NOUN
fnp-2955	40	26	methanethiosulfonate	methanethiosulfonate	NOUN
fnp-2955	40	27	at	at	ADP
fnp-2955	40	28	room	room	NOUN
fnp-2955	40	29	temperature	temperature	NOUN
fnp-2955	40	30	for	for	ADP
fnp-2955	40	31	10	10	NUM
fnp-2955	40	32	min	min	NOUN
fnp-2955	40	33	.	.	NOUN
fnp-2955	40	34	proteins	protein	NOUN
fnp-2955	40	35	were	be	AUX
fnp-2955	40	36	enzymatically	enzymatically	ADV
fnp-2955	40	37	digested	digest	VERB
fnp-2955	40	38	using	use	VERB
fnp-2955	40	39	trypsin	trypsin	NOUN
fnp-2955	40	40	overnight	overnight	ADV
fnp-2955	40	41	in	in	ADP
fnp-2955	40	42	dark	dark	ADJ
fnp-2955	40	43	at	at	ADP
fnp-2955	40	44	37	37	NUM
fnp-2955	41	1	°	°	ADP
fnp-2955	41	2	c	c	NOUN
fnp-2955	41	3	(	(	PUNCT
fnp-2955	41	4	sigma	sigma	PROPN
fnp-2955	41	5	aldrich	aldrich	PROPN
fnp-2955	41	6	,	,	PUNCT
fnp-2955	41	7	st	st	PROPN
fnp-2955	41	8	.	.	PROPN
fnp-2955	41	9	louis	louis	PROPN
fnp-2955	41	10	,	,	PUNCT
fnp-2955	41	11	mo	mo	PROPN
fnp-2955	41	12	,	,	PUNCT
fnp-2955	41	13	usa	usa	PROPN
fnp-2955	41	14	)	)	PUNCT
fnp-2955	41	15	.	.	PUNCT
fnp-2955	42	1	peptides	peptide	NOUN
fnp-2955	42	2	from	from	ADP
fnp-2955	42	3	each	each	DET
fnp-2955	42	4	sample	sample	NOUN
fnp-2955	42	5	were	be	AUX
fnp-2955	42	6	labelled	label	VERB
fnp-2955	42	7	using	use	VERB
fnp-2955	42	8	the	the	DET
fnp-2955	42	9	10plex	10plex	PROPN
fnp-2955	42	10	tandem	tandem	PROPN
fnp-2955	42	11	mass	mass	PROPN
fnp-2955	42	12	tag	tag	NOUN
fnp-2955	42	13	(	(	PUNCT
fnp-2955	42	14	tmt	tmt	PROPN
fnp-2955	42	15	)	)	PUNCT
fnp-2955	42	16	reagent	reagent	ADJ
fnp-2955	42	17	kit	kit	NOUN
fnp-2955	42	18	(	(	PUNCT
fnp-2955	42	19	thermo	thermo	NOUN
fnp-2955	42	20	fisher	fisher	PROPN
fnp-2955	42	21	scientific	scientific	PROPN
fnp-2955	42	22	,	,	PUNCT
fnp-2955	42	23	waltham	waltham	PROPN
fnp-2955	42	24	,	,	PUNCT
fnp-2955	42	25	ma	ma	PROPN
fnp-2955	42	26	,	,	PUNCT
fnp-2955	42	27	us	we	PRON
fnp-2955	42	28	)	)	PUNCT
fnp-2955	42	29	.	.	PUNCT
fnp-2955	43	1	labelled	label	VERB
fnp-2955	43	2	peptides	peptide	NOUN
fnp-2955	43	3	were	be	AUX
fnp-2955	43	4	mixed	mixed	ADJ
fnp-2955	43	5	and	and	CCONJ
fnp-2955	43	6	analyzed	analyze	VERB
fnp-2955	43	7	using	use	VERB
fnp-2955	43	8	two	two	NUM
fnp-2955	43	9	-	-	PUNCT
fnp-2955	43	10	dimensional	dimensional	ADJ
fnp-2955	43	11	liquid	liquid	ADJ
fnp-2955	43	12	chromatography	chromatography	NOUN
fnp-2955	43	13	and	and	CCONJ
fnp-2955	43	14	tandem	tandem	NOUN
fnp-2955	43	15	mass	mass	ADJ
fnp-2955	43	16	spectrometry	spectrometry	NOUN
fnp-2955	43	17	as	as	SCONJ
fnp-2955	43	18	reported	report	VERB
fnp-2955	43	19	previously	previously	ADV
fnp-2955	43	20	(	(	PUNCT
fnp-2955	43	21	17	17	NUM
fnp-2955	43	22	)	)	PUNCT
fnp-2955	43	23	.	.	PUNCT
fnp-2955	44	1	database	database	NOUN
fnp-2955	44	2	searching	search	VERB
fnp-2955	44	3	unprocessed	unprocesse	VERB
fnp-2955	44	4	raw	raw	ADJ
fnp-2955	44	5	files	file	NOUN
fnp-2955	44	6	were	be	AUX
fnp-2955	44	7	submitted	submit	VERB
fnp-2955	44	8	to	to	ADP
fnp-2955	44	9	proteome	proteome	VERB
fnp-2955	44	10	discoverer	discoverer	X
fnp-2955	44	11	1.4	1.4	NUM
fnp-2955	44	12	(	(	PUNCT
fnp-2955	44	13	thermo	thermo	NOUN
fnp-2955	44	14	fisher	fisher	PROPN
fnp-2955	44	15	scientific	scientific	PROPN
fnp-2955	44	16	,	,	PUNCT
fnp-2955	44	17	waltham	waltham	PROPN
fnp-2955	44	18	,	,	PUNCT
fnp-2955	44	19	ma	ma	PROPN
fnp-2955	44	20	,	,	PUNCT
fnp-2955	44	21	us	we	PRON
fnp-2955	44	22	)	)	PUNCT
fnp-2955	44	23	for	for	ADP
fnp-2955	44	24	target	target	NOUN
fnp-2955	44	25	decoy	decoy	NOUN
fnp-2955	44	26	search	search	NOUN
fnp-2955	44	27	using	use	VERB
fnp-2955	44	28	sequest	sequest	NOUN
fnp-2955	44	29	.	.	PUNCT
fnp-2955	45	1	the	the	DET
fnp-2955	45	2	uniprotkb	uniprotkb	ADJ
fnp-2955	45	3	homo	homo	NOUN
fnp-2955	45	4	sapiens	sapiens	PART
fnp-2955	45	5	database	database	NOUN
fnp-2955	45	6	which	which	PRON
fnp-2955	45	7	comprised	comprise	VERB
fnp-2955	45	8	20,159	20,159	NUM
fnp-2955	45	9	entries	entry	NOUN
fnp-2955	45	10	(	(	PUNCT
fnp-2955	45	11	release	release	NOUN
fnp-2955	45	12	date	date	NOUN
fnp-2955	45	13	january	january	PROPN
fnp-2955	45	14	2015	2015	NUM
fnp-2955	45	15	)	)	PUNCT
fnp-2955	45	16	was	be	AUX
fnp-2955	45	17	utilized	utilize	VERB
fnp-2955	45	18	.	.	PUNCT
fnp-2955	46	1	the	the	DET
fnp-2955	46	2	search	search	NOUN
fnp-2955	46	3	allowed	allow	VERB
fnp-2955	46	4	for	for	ADP
fnp-2955	46	5	up	up	ADP
fnp-2955	46	6	to	to	PART
fnp-2955	46	7	two	two	NUM
fnp-2955	46	8	missed	miss	VERB
fnp-2955	46	9	cleavages	cleavage	NOUN
fnp-2955	46	10	,	,	PUNCT
fnp-2955	46	11	a	a	DET
fnp-2955	46	12	precursor	precursor	NOUN
fnp-2955	46	13	mass	mass	NOUN
fnp-2955	46	14	tolerance	tolerance	NOUN
fnp-2955	46	15	of	of	ADP
fnp-2955	46	16	10ppm	10ppm	NOUN
fnp-2955	46	17	,	,	PUNCT
fnp-2955	46	18	a	a	DET
fnp-2955	46	19	minimum	minimum	NOUN
fnp-2955	46	20	peptide	peptide	NOUN
fnp-2955	46	21	length	length	NOUN
fnp-2955	46	22	of	of	ADP
fnp-2955	46	23	six	six	NUM
fnp-2955	46	24	and	and	CCONJ
fnp-2955	46	25	a	a	DET
fnp-2955	46	26	maximum	maximum	NOUN
fnp-2955	46	27	of	of	ADP
fnp-2955	46	28	two	two	NUM
fnp-2955	46	29	variable	variable	NOUN
fnp-2955	46	30	(	(	PUNCT
fnp-2955	46	31	one	one	NUM
fnp-2955	46	32	equal	equal	ADJ
fnp-2955	46	33	)	)	PUNCT
fnp-2955	46	34	modifications	modification	NOUN
fnp-2955	46	35	of	of	ADP
fnp-2955	46	36	;	;	PUNCT
fnp-2955	46	37	oxidation	oxidation	X
fnp-2955	46	38	(	(	PUNCT
fnp-2955	46	39	m	m	NOUN
fnp-2955	46	40	)	)	PUNCT
fnp-2955	46	41	,	,	PUNCT
fnp-2955	46	42	deamidation	deamidation	NOUN
fnp-2955	46	43	(	(	PUNCT
fnp-2955	46	44	n	n	CCONJ
fnp-2955	46	45	,	,	PUNCT
fnp-2955	46	46	q	q	NOUN
fnp-2955	46	47	)	)	PUNCT
fnp-2955	46	48	,	,	PUNCT
fnp-2955	46	49	or	or	CCONJ
fnp-2955	46	50	phosphorylation	phosphorylation	NOUN
fnp-2955	46	51	(	(	PUNCT
fnp-2955	46	52	s	s	PROPN
fnp-2955	46	53	,	,	PUNCT
fnp-2955	46	54	t	t	PROPN
fnp-2955	46	55	,	,	PUNCT
fnp-2955	46	56	y	y	PROPN
fnp-2955	46	57	)	)	PUNCT
fnp-2955	46	58	.	.	PUNCT
fnp-2955	47	1	methylthio	methylthio	NOUN
fnp-2955	47	2	(	(	PUNCT
fnp-2955	47	3	c	c	NOUN
fnp-2955	47	4	)	)	PUNCT
fnp-2955	47	5	and	and	CCONJ
fnp-2955	47	6	tmt	tmt	PROPN
fnp-2955	47	7	6	6	NUM
fnp-2955	47	8	-	-	PUNCT
fnp-2955	47	9	plex	plex	NOUN
fnp-2955	47	10	(	(	PUNCT
fnp-2955	47	11	k	k	X
fnp-2955	47	12	,	,	PUNCT
fnp-2955	47	13	y	y	PROPN
fnp-2955	47	14	and	and	CCONJ
fnp-2955	47	15	n	n	CCONJ
fnp-2955	47	16	-	-	PUNCT
fnp-2955	47	17	terminus	terminus	NOUN
fnp-2955	47	18	)	)	PUNCT
fnp-2955	47	19	were	be	AUX
fnp-2955	47	20	set	set	VERB
fnp-2955	47	21	as	as	ADP
fnp-2955	47	22	fixed	fix	VERB
fnp-2955	47	23	modifications	modification	NOUN
fnp-2955	47	24	.	.	PUNCT
fnp-2955	48	1	false	false	ADJ
fnp-2955	48	2	discovery	discovery	NOUN
fnp-2955	48	3	rate	rate	NOUN
fnp-2955	48	4	(	(	PUNCT
fnp-2955	48	5	fdr	fdr	PROPN
fnp-2955	48	6	)	)	PUNCT
fnp-2955	48	7	corrected	correct	VERB
fnp-2955	48	8	p	p	NOUN
fnp-2955	48	9	value	value	NOUN
fnp-2955	48	10	at	at	ADP
fnp-2955	48	11	the	the	DET
fnp-2955	48	12	peptide	peptide	ADJ
fnp-2955	48	13	level	level	NOUN
fnp-2955	48	14	was	be	AUX
fnp-2955	48	15	set	set	VERB
fnp-2955	48	16	at	at	ADP
fnp-2955	48	17	<	<	X
fnp-2955	48	18	0.05	0.05	NUM
fnp-2955	48	19	.	.	PUNCT
fnp-2955	49	1	percent	percent	NOUN
fnp-2955	49	2	co	co	NOUN
fnp-2955	49	3	-	-	NOUN
fnp-2955	49	4	isolation	isolation	NOUN
fnp-2955	49	5	excluding	exclude	VERB
fnp-2955	49	6	peptides	peptide	NOUN
fnp-2955	49	7	from	from	ADP
fnp-2955	49	8	quantitation	quantitation	NOUN
fnp-2955	49	9	was	be	AUX
fnp-2955	49	10	set	set	VERB
fnp-2955	49	11	at	at	ADP
fnp-2955	49	12	50	50	NUM
fnp-2955	49	13	.	.	PUNCT
fnp-2955	50	1	reporter	reporter	NOUN
fnp-2955	50	2	ion	ion	NOUN
fnp-2955	50	3	ratios	ratio	NOUN
fnp-2955	50	4	from	from	ADP
fnp-2955	50	5	unique	unique	ADJ
fnp-2955	50	6	peptides	peptide	NOUN
fnp-2955	50	7	only	only	ADV
fnp-2955	50	8	were	be	AUX
fnp-2955	50	9	taken	take	VERB
fnp-2955	50	10	into	into	ADP
fnp-2955	50	11	consideration	consideration	NOUN
fnp-2955	50	12	for	for	ADP
fnp-2955	50	13	the	the	DET
fnp-2955	50	14	quantitation	quantitation	NOUN
fnp-2955	50	15	of	of	ADP
fnp-2955	50	16	the	the	DET
fnp-2955	50	17	respective	respective	ADJ
fnp-2955	50	18	protein	protein	NOUN
fnp-2955	50	19	.	.	PUNCT
fnp-2955	51	1	quantitation	quantitation	NOUN
fnp-2955	51	2	per	per	ADP
fnp-2955	51	3	protein	protein	NOUN
fnp-2955	51	4	in	in	ADP
fnp-2955	51	5	each	each	PRON
fnp-2955	51	6	of	of	ADP
fnp-2955	51	7	the	the	DET
fnp-2955	51	8	six	six	NUM
fnp-2955	51	9	caa	caa	NOUN
fnp-2955	51	10	patients	patient	NOUN
fnp-2955	51	11	was	be	AUX
fnp-2955	51	12	divided	divide	VERB
fnp-2955	51	13	by	by	ADP
fnp-2955	51	14	each	each	PRON
fnp-2955	51	15	of	of	ADP
fnp-2955	51	16	the	the	DET
fnp-2955	51	17	two	two	NUM
fnp-2955	51	18	matched	match	VERB
fnp-2955	51	19	same	same	ADJ
fnp-2955	51	20	sex	sex	NOUN
fnp-2955	51	21	controls	control	NOUN
fnp-2955	51	22	,	,	PUNCT
fnp-2955	51	23	which	which	PRON
fnp-2955	51	24	yielded	yield	VERB
fnp-2955	51	25	12	12	NUM
fnp-2955	51	26	quantitative	quantitative	ADJ
fnp-2955	51	27	ratios	ratio	NOUN
fnp-2955	51	28	per	per	ADP
fnp-2955	51	29	protein	protein	NOUN
fnp-2955	51	30	.	.	PUNCT
fnp-2955	52	1	these	these	DET
fnp-2955	52	2	ratios	ratio	NOUN
fnp-2955	52	3	,	,	PUNCT
fnp-2955	52	4	which	which	PRON
fnp-2955	52	5	represent	represent	VERB
fnp-2955	52	6	the	the	DET
fnp-2955	52	7	overall	overall	ADJ
fnp-2955	52	8	fold	fold	ADJ
fnp-2955	52	9	change	change	NOUN
fnp-2955	52	10	in	in	ADP
fnp-2955	52	11	protein	protein	NOUN
fnp-2955	52	12	in	in	ADP
fnp-2955	52	13	the	the	DET
fnp-2955	52	14	caa	caa	NOUN
fnp-2955	52	15	patients	patient	NOUN
fnp-2955	52	16	with	with	ADP
fnp-2955	52	17	respect	respect	NOUN
fnp-2955	52	18	to	to	ADP
fnp-2955	52	19	the	the	DET
fnp-2955	52	20	controls	control	NOUN
fnp-2955	52	21	,	,	PUNCT
fnp-2955	52	22	were	be	AUX
fnp-2955	52	23	median	median	NOUN
fnp-2955	52	24	-	-	PUNCT
fnp-2955	52	25	normalized	normalize	VERB
fnp-2955	52	26	and	and	CCONJ
fnp-2955	52	27	log2	log2	PROPN
fnp-2955	52	28	transformed	transform	VERB
fnp-2955	52	29	.	.	PUNCT
fnp-2955	53	1	we	we	PRON
fnp-2955	53	2	then	then	ADV
fnp-2955	53	3	combined	combine	VERB
fnp-2955	53	4	the	the	DET
fnp-2955	53	5	two	two	NUM
fnp-2955	53	6	respective	respective	ADJ
fnp-2955	53	7	log2	log2	PROPN
fnp-2955	53	8	ratios	ratio	NOUN
fnp-2955	53	9	per	per	ADP
fnp-2955	53	10	caa	caa	NOUN
fnp-2955	53	11	patient	patient	NOUN
fnp-2955	53	12	when	when	SCONJ
fnp-2955	53	13	compared	compare	VERB
fnp-2955	53	14	to	to	ADP
fnp-2955	53	15	the	the	DET
fnp-2955	53	16	two	two	NUM
fnp-2955	53	17	controls	control	NOUN
fnp-2955	53	18	by	by	ADP
fnp-2955	53	19	their	their	PRON
fnp-2955	53	20	mean	mean	NOUN
fnp-2955	53	21	which	which	PRON
fnp-2955	53	22	generated	generate	VERB
fnp-2955	53	23	one	one	NUM
fnp-2955	53	24	observation	observation	NOUN
fnp-2955	53	25	per	per	ADP
fnp-2955	53	26	caa	caa	NOUN
fnp-2955	53	27	patient	patient	NOUN
fnp-2955	53	28	per	per	ADP
fnp-2955	53	29	protein	protein	NOUN
fnp-2955	53	30	(	(	PUNCT
fnp-2955	53	31	see	see	VERB
fnp-2955	53	32	supplementary	supplementary	ADJ
fnp-2955	53	33	table	table	NOUN
fnp-2955	53	34	1	1	NUM
fnp-2955	53	35	)	)	PUNCT
fnp-2955	53	36	.	.	PUNCT
fnp-2955	54	1	due	due	ADP
fnp-2955	54	2	to	to	ADP
fnp-2955	54	3	small	small	ADJ
fnp-2955	54	4	sample	sample	NOUN
fnp-2955	54	5	size	size	NOUN
fnp-2955	54	6	,	,	PUNCT
fnp-2955	54	7	statistical	statistical	ADJ
fnp-2955	54	8	analysis	analysis	NOUN
fnp-2955	54	9	was	be	AUX
fnp-2955	54	10	performed	perform	VERB
fnp-2955	54	11	per	per	ADP
fnp-2955	54	12	protein	protein	NOUN
fnp-2955	54	13	regardless	regardless	ADV
fnp-2955	54	14	of	of	ADP
fnp-2955	54	15	gender	gender	NOUN
fnp-2955	54	16	(	(	PUNCT
fnp-2955	54	17	n=6	n=6	NOUN
fnp-2955	54	18	)	)	PUNCT
fnp-2955	54	19	.	.	PUNCT
fnp-2955	55	1	based	base	VERB
fnp-2955	55	2	on	on	ADP
fnp-2955	55	3	a	a	DET
fnp-2955	55	4	previous	previous	ADJ
fnp-2955	55	5	study	study	NOUN
fnp-2955	55	6	(	(	PUNCT
fnp-2955	55	7	16	16	NUM
fnp-2955	55	8	)	)	PUNCT
fnp-2955	55	9	,	,	PUNCT
fnp-2955	55	10	we	we	PRON
fnp-2955	55	11	set	set	VERB
fnp-2955	55	12	the	the	DET
fnp-2955	55	13	cut	cut	ADJ
fnp-2955	55	14	point	point	NOUN
fnp-2955	55	15	of	of	ADP
fnp-2955	55	16	log2	log2	PROPN
fnp-2955	55	17	ratio	ratio	NOUN
fnp-2955	55	18	higher	high	ADJ
fnp-2955	55	19	than	than	ADP
fnp-2955	55	20	or	or	CCONJ
fnp-2955	55	21	equals	equal	VERB
fnp-2955	55	22	to	to	ADP
fnp-2955	55	23	0.6	0.6	NUM
fnp-2955	55	24	,	,	PUNCT
fnp-2955	55	25	or	or	CCONJ
fnp-2955	55	26	lower	low	ADJ
fnp-2955	55	27	than	than	ADP
fnp-2955	55	28	or	or	CCONJ
fnp-2955	55	29	equals	equal	VERB
fnp-2955	55	30	to	to	ADP
fnp-2955	55	31	-0.6	-0.6	NOUN
fnp-2955	55	32	to	to	PART
fnp-2955	55	33	identify	identify	VERB
fnp-2955	55	34	differentially	differentially	ADV
fnp-2955	55	35	expressed	express	VERB
fnp-2955	55	36	proteins	protein	NOUN
fnp-2955	55	37	(	(	PUNCT
fnp-2955	55	38	deps	dep	NOUN
fnp-2955	55	39	)	)	PUNCT
fnp-2955	55	40	(	(	PUNCT
fnp-2955	55	41	equivalent	equivalent	ADJ
fnp-2955	55	42	to	to	ADP
fnp-2955	55	43	a	a	DET
fnp-2955	55	44	1.5	1.5	NUM
fnp-2955	55	45	-	-	ADJ
fnp-2955	55	46	fold	fold	ADJ
fnp-2955	55	47	change	change	NOUN
fnp-2955	55	48	)	)	PUNCT
fnp-2955	55	49	,	,	PUNCT
fnp-2955	55	50	but	but	CCONJ
fnp-2955	55	51	this	this	PRON
fnp-2955	55	52	was	be	AUX
fnp-2955	55	53	considered	consider	VERB
fnp-2955	55	54	too	too	ADV
fnp-2955	55	55	restrictive	restrictive	ADJ
fnp-2955	55	56	for	for	ADP
fnp-2955	55	57	complex	complex	ADJ
fnp-2955	55	58	structure	structure	NOUN
fnp-2955	55	59	such	such	ADJ
fnp-2955	55	60	as	as	ADP
fnp-2955	55	61	the	the	DET
fnp-2955	55	62	white	white	ADJ
fnp-2955	55	63	matter	matter	NOUN
fnp-2955	55	64	(	(	PUNCT
fnp-2955	55	65	number	number	NOUN
fnp-2955	55	66	of	of	ADP
fnp-2955	55	67	proteins	protein	NOUN
fnp-2955	55	68	included	include	VERB
fnp-2955	55	69	=	=	PROPN
fnp-2955	55	70	51	51	NUM
fnp-2955	55	71	)	)	PUNCT
fnp-2955	55	72	.	.	PUNCT
fnp-2955	56	1	hence	hence	ADV
fnp-2955	56	2	,	,	PUNCT
fnp-2955	56	3	we	we	PRON
fnp-2955	56	4	have	have	AUX
fnp-2955	56	5	narrowed	narrow	VERB
fnp-2955	56	6	the	the	DET
fnp-2955	56	7	gap	gap	NOUN
fnp-2955	56	8	by	by	ADP
fnp-2955	56	9	halving	halve	VERB
fnp-2955	56	10	the	the	DET
fnp-2955	56	11	cut	cut	NOUN
fnp-2955	56	12	point	point	NOUN
fnp-2955	56	13	to	to	ADP
fnp-2955	56	14	±0.3	±0.3	PROPN
fnp-2955	56	15	(	(	PUNCT
fnp-2955	56	16	equivalent	equivalent	ADJ
fnp-2955	56	17	to	to	ADP
fnp-2955	56	18	1.2	1.2	NUM
fnp-2955	56	19	-	-	ADJ
fnp-2955	56	20	fold	fold	ADJ
fnp-2955	56	21	change	change	NOUN
fnp-2955	56	22	)	)	PUNCT
fnp-2955	56	23	instead	instead	ADV
fnp-2955	56	24	in	in	ADP
fnp-2955	56	25	this	this	DET
fnp-2955	56	26	study	study	NOUN
fnp-2955	56	27	(	(	PUNCT
fnp-2955	56	28	number	number	NOUN
fnp-2955	56	29	of	of	ADP
fnp-2955	56	30	proteins	protein	NOUN
fnp-2955	56	31	included	include	VERB
fnp-2955	56	32	=	=	NOUN
fnp-2955	56	33	189	189	NUM
fnp-2955	56	34	)	)	PUNCT
fnp-2955	56	35	.	.	PUNCT
fnp-2955	57	1	proteins	protein	NOUN
fnp-2955	57	2	identified	identify	VERB
fnp-2955	57	3	with	with	ADP
fnp-2955	57	4	at	at	ADV
fnp-2955	57	5	least	least	ADV
fnp-2955	57	6	two	two	NUM
fnp-2955	57	7	unique	unique	ADJ
fnp-2955	57	8	peptides	peptide	NOUN
fnp-2955	57	9	were	be	AUX
fnp-2955	57	10	included	include	VERB
fnp-2955	57	11	in	in	ADP
fnp-2955	57	12	the	the	DET
fnp-2955	57	13	analysis	analysis	NOUN
fnp-2955	57	14	.	.	PUNCT
fnp-2955	58	1	one	one	NUM
fnp-2955	58	2	-	-	PUNCT
fnp-2955	58	3	sample	sample	NOUN
fnp-2955	58	4	t	t	PROPN
fnp-2955	58	5	test	test	NOUN
fnp-2955	58	6	was	be	AUX
fnp-2955	58	7	performed	perform	VERB
fnp-2955	58	8	on	on	ADP
fnp-2955	58	9	these	these	DET
fnp-2955	58	10	log2	log2	PROPN
fnp-2955	58	11	ratios	ratio	NOUN
fnp-2955	58	12	per	per	ADP
fnp-2955	58	13	protein	protein	NOUN
fnp-2955	58	14	,	,	PUNCT
fnp-2955	58	15	comparing	compare	VERB
fnp-2955	58	16	to	to	ADP
fnp-2955	58	17	0	0	NUM
fnp-2955	58	18	,	,	PUNCT
fnp-2955	58	19	to	to	PART
fnp-2955	58	20	identify	identify	VERB
fnp-2955	58	21	the	the	DET
fnp-2955	58	22	proteins	protein	NOUN
fnp-2955	58	23	that	that	PRON
fnp-2955	58	24	were	be	AUX
fnp-2955	58	25	statistically	statistically	ADV
fnp-2955	58	26	significant	significant	ADJ
fnp-2955	58	27	and	and	CCONJ
fnp-2955	58	28	differentially	differentially	ADV
fnp-2955	58	29	expressed	express	VERB
fnp-2955	58	30	in	in	ADP
fnp-2955	58	31	caa	caa	NOUN
fnp-2955	58	32	patients	patient	NOUN
fnp-2955	58	33	comparing	compare	VERB
fnp-2955	58	34	to	to	ADP
fnp-2955	58	35	controls	control	NOUN
fnp-2955	58	36	(	(	PUNCT
fnp-2955	58	37	p	p	X
fnp-2955	58	38	<	<	X
fnp-2955	58	39	0.05	0.05	NUM
fnp-2955	58	40	)	)	PUNCT
fnp-2955	58	41	.	.	PUNCT
fnp-2955	59	1	bioinformatics	bioinformatics	NOUN
fnp-2955	59	2	analysis	analysis	NOUN
fnp-2955	59	3	ingenuity	ingenuity	NOUN
fnp-2955	59	4	pathway	pathway	NOUN
fnp-2955	59	5	analysis	analysis	NOUN
fnp-2955	59	6	(	(	PUNCT
fnp-2955	59	7	ipa	ipa	PROPN
fnp-2955	59	8	)	)	PUNCT
fnp-2955	59	9	(	(	PUNCT
fnp-2955	59	10	qiagen	qiagen	PROPN
fnp-2955	59	11	,	,	PUNCT
fnp-2955	59	12	hilden	hilden	PROPN
fnp-2955	59	13	,	,	PUNCT
fnp-2955	59	14	germany	germany	PROPN
fnp-2955	59	15	)	)	PUNCT
fnp-2955	59	16	and	and	CCONJ
fnp-2955	59	17	metacore	metacore	X
fnp-2955	59	18	(	(	PUNCT
fnp-2955	59	19	clarivate	clarivate	NOUN
fnp-2955	59	20	analytics	analytic	NOUN
fnp-2955	59	21	,	,	PUNCT
fnp-2955	59	22	philadelphia	philadelphia	PROPN
fnp-2955	59	23	,	,	PUNCT
fnp-2955	59	24	pa	pa	PROPN
fnp-2955	59	25	,	,	PUNCT
fnp-2955	59	26	usa	usa	PROPN
fnp-2955	59	27	)	)	PUNCT
fnp-2955	59	28	were	be	AUX
fnp-2955	59	29	used	use	VERB
fnp-2955	59	30	to	to	PART
fnp-2955	59	31	identify	identify	VERB
fnp-2955	59	32	significantly	significantly	ADV
fnp-2955	59	33	enriched	enrich	VERB
fnp-2955	59	34	processes	process	NOUN
fnp-2955	59	35	and	and	CCONJ
fnp-2955	59	36	pathways	pathway	NOUN
fnp-2955	59	37	in	in	ADP
fnp-2955	59	38	the	the	DET
fnp-2955	59	39	differentially	differentially	ADV
fnp-2955	59	40	expressed	express	VERB
fnp-2955	59	41	proteins	protein	NOUN
fnp-2955	59	42	of	of	ADP
fnp-2955	59	43	white	white	ADJ
fnp-2955	59	44	matter	matter	NOUN
fnp-2955	59	45	from	from	ADP
fnp-2955	59	46	patients	patient	NOUN
fnp-2955	59	47	with	with	ADP
fnp-2955	59	48	caa	caa	PROPN
fnp-2955	59	49	vs.	vs.	ADP
fnp-2955	59	50	control	control	NOUN
fnp-2955	59	51	.	.	PUNCT
fnp-2955	60	1	p	p	NOUN
fnp-2955	60	2	values	value	NOUN
fnp-2955	60	3	in	in	ADP
fnp-2955	60	4	the	the	DET
fnp-2955	60	5	context	context	NOUN
fnp-2955	60	6	of	of	ADP
fnp-2955	60	7	canonical	canonical	ADJ
fnp-2955	60	8	pathway	pathway	NOUN
fnp-2955	60	9	analysis	analysis	NOUN
fnp-2955	60	10	reflect	reflect	VERB
fnp-2955	60	11	how	how	SCONJ
fnp-2955	60	12	significantly	significantly	ADV
fnp-2955	60	13	the	the	DET
fnp-2955	60	14	pathway	pathway	NOUN
fnp-2955	60	15	is	be	AUX
fnp-2955	60	16	over	over	ADV
fnp-2955	60	17	-	-	PUNCT
fnp-2955	60	18	represented	represent	VERB
fnp-2955	60	19	in	in	ADP
fnp-2955	60	20	the	the	DET
fnp-2955	60	21	dataset	dataset	NOUN
fnp-2955	60	22	of	of	ADP
fnp-2955	60	23	deps	dep	NOUN
fnp-2955	60	24	in	in	ADP
fnp-2955	60	25	white	white	ADJ
fnp-2955	60	26	matter	matter	NOUN
fnp-2955	60	27	from	from	ADP
fnp-2955	60	28	patients	patient	NOUN
fnp-2955	60	29	with	with	ADP
fnp-2955	60	30	caa	caa	PROPN
fnp-2955	60	31	vs.	vs.	ADP
fnp-2955	60	32	controls	control	NOUN
fnp-2955	60	33	.	.	PUNCT
fnp-2955	61	1	significance	significance	NOUN
fnp-2955	61	2	was	be	AUX
fnp-2955	61	3	set	set	VERB
fnp-2955	61	4	at	at	ADP
fnp-2955	61	5	p	p	NOUN
fnp-2955	61	6	<	<	X
fnp-2955	61	7	0.05	0.05	NUM
fnp-2955	61	8	.	.	PUNCT
fnp-2955	62	1	results	result	VERB
fnp-2955	62	2	the	the	DET
fnp-2955	62	3	global	global	ADJ
fnp-2955	62	4	,	,	PUNCT
fnp-2955	62	5	untargeted	untargeted	ADJ
fnp-2955	62	6	proteomic	proteomic	ADJ
fnp-2955	62	7	analysis	analysis	NOUN
fnp-2955	62	8	resulted	result	VERB
fnp-2955	62	9	in	in	ADP
fnp-2955	62	10	the	the	DET
fnp-2955	62	11	profiling	profiling	NOUN
fnp-2955	62	12	of	of	ADP
fnp-2955	62	13	3,734	3,734	NUM
fnp-2955	62	14	proteins	protein	NOUN
fnp-2955	62	15	(	(	PUNCT
fnp-2955	62	16	peptide	peptide	NOUN
fnp-2955	62	17	fdr	fdr	PROPN
fnp-2955	62	18	p<0.05	p<0.05	PROPN
fnp-2955	62	19	)	)	PUNCT
fnp-2955	62	20	(	(	PUNCT
fnp-2955	62	21	supplementary	supplementary	ADJ
fnp-2955	62	22	tables	table	NOUN
fnp-2955	62	23	1	1	NUM
fnp-2955	62	24	,	,	PUNCT
fnp-2955	62	25	2	2	NUM
fnp-2955	62	26	,	,	PUNCT
fnp-2955	62	27	3	3	NUM
fnp-2955	62	28	)	)	PUNCT
fnp-2955	62	29	.	.	PUNCT
fnp-2955	63	1	of	of	ADP
fnp-2955	63	2	these	these	PRON
fnp-2955	63	3	,	,	PUNCT
fnp-2955	63	4	189	189	NUM
fnp-2955	63	5	were	be	AUX
fnp-2955	63	6	differentially	differentially	ADV
fnp-2955	63	7	expressed	express	VERB
fnp-2955	63	8	in	in	ADP
fnp-2955	63	9	caa	caa	PROPN
fnp-2955	63	10	(	(	PUNCT
fnp-2955	63	11	supplementary	supplementary	ADJ
fnp-2955	63	12	table	table	NOUN
fnp-2955	63	13	4	4	NUM
fnp-2955	63	14	)	)	PUNCT
fnp-2955	63	15	.	.	PUNCT
fnp-2955	64	1	bioinformatics	bioinformatics	NOUN
fnp-2955	64	2	analysis	analysis	NOUN
fnp-2955	64	3	of	of	ADP
fnp-2955	64	4	the	the	DET
fnp-2955	64	5	differentially	differentially	ADV
fnp-2955	64	6	expressed	express	VERB
fnp-2955	64	7	proteins	protein	NOUN
fnp-2955	64	8	(	(	PUNCT
fnp-2955	64	9	deps	dep	NOUN
fnp-2955	64	10	)	)	PUNCT
fnp-2955	64	11	using	use	VERB
fnp-2955	64	12	metacore	metacore	ADV
fnp-2955	64	13	showed	show	VERB
fnp-2955	64	14	significant	significant	ADJ
fnp-2955	64	15	enrichment	enrichment	NOUN
fnp-2955	64	16	of	of	ADP
fnp-2955	64	17	the	the	DET
fnp-2955	64	18	cell	cell	NOUN
fnp-2955	64	19	adhesion	adhesion	NOUN
fnp-2955	64	20	|	|	NOUN
fnp-2955	64	21	cell	cell	NOUN
fnp-2955	64	22	-	-	PUNCT
fnp-2955	64	23	matrix	matrix	NOUN
fnp-2955	64	24	interaction	interaction	NOUN
fnp-2955	64	25	process	process	NOUN
fnp-2955	64	26	(	(	PUNCT
fnp-2955	64	27	figure	figure	NOUN
fnp-2955	64	28	2	2	NUM
fnp-2955	64	29	)	)	PUNCT
fnp-2955	64	30	.	.	PUNCT
fnp-2955	65	1	mapping	mapping	NOUN
fnp-2955	65	2	on	on	ADP
fnp-2955	65	3	this	this	DET
fnp-2955	65	4	process	process	NOUN
fnp-2955	65	5	network	network	NOUN
fnp-2955	65	6	,	,	PUNCT
fnp-2955	65	7	emilin-2	emilin-2	PROPN
fnp-2955	65	8	(	(	PUNCT
fnp-2955	65	9	emilin2	emilin2	NOUN
fnp-2955	65	10	)	)	PUNCT
fnp-2955	65	11	,	,	PUNCT
fnp-2955	65	12	fibrillin-1	fibrillin-1	PROPN
fnp-2955	65	13	(	(	PUNCT
fnp-2955	65	14	fbn1	fbn1	PROPN
fnp-2955	65	15	)	)	PUNCT
fnp-2955	65	16	,	,	PUNCT
fnp-2955	65	17	collagen	collagen	PROPN
fnp-2955	65	18	alpha-2(iv	alpha-2(iv	PROPN
fnp-2955	65	19	)	)	PUNCT
fnp-2955	65	20	(	(	PUNCT
fnp-2955	65	21	col4a2	col4a2	PROPN
fnp-2955	65	22	)	)	PUNCT
fnp-2955	65	23	and	and	CCONJ
fnp-2955	65	24	the	the	DET
fnp-2955	65	25	extracellular	extracellular	ADJ
fnp-2955	65	26	protein	protein	NOUN
fnp-2955	65	27	heparan	heparan	ADJ
fnp-2955	65	28	sulfate	sulfate	NOUN
fnp-2955	65	29	proteoglycan	proteoglycan	NOUN
fnp-2955	65	30	(	(	PUNCT
fnp-2955	65	31	hspg2	hspg2	PROPN
fnp-2955	65	32	)	)	PUNCT
fnp-2955	65	33	were	be	AUX
fnp-2955	65	34	upregulated	upregulate	VERB
fnp-2955	65	35	;	;	PUNCT
fnp-2955	65	36	inter	inter	ADJ
fnp-2955	65	37	-	-	ADJ
fnp-2955	65	38	alpha	alpha	ADJ
fnp-2955	65	39	trypsin	trypsin	NOUN
fnp-2955	65	40	inhibitor	inhibitor	NOUN
fnp-2955	65	41	heavy	heavy	ADJ
fnp-2955	65	42	chain	chain	NOUN
fnp-2955	65	43	h3	h3	NOUN
fnp-2955	65	44	(	(	PUNCT
fnp-2955	65	45	itih3	itih3	NOUN
fnp-2955	65	46	)	)	PUNCT
fnp-2955	65	47	was	be	AUX
fnp-2955	65	48	downregulated	downregulate	VERB
fnp-2955	65	49	in	in	ADP
fnp-2955	65	50	caa	caa	NOUN
fnp-2955	65	51	vs.	vs.	ADP
fnp-2955	65	52	control	control	PROPN
fnp-2955	65	53	.	.	PUNCT
fnp-2955	66	1	figure	figure	NOUN
fnp-2955	66	2	3	3	NUM
fnp-2955	66	3	is	be	AUX
fnp-2955	66	4	a	a	DET
fnp-2955	66	5	bar	bar	NOUN
fnp-2955	66	6	graph	graph	NOUN
fnp-2955	66	7	showing	show	VERB
fnp-2955	66	8	the	the	DET
fnp-2955	66	9	relative	relative	ADJ
fnp-2955	66	10	expression	expression	NOUN
fnp-2955	66	11	levels	level	NOUN
fnp-2955	66	12	of	of	ADP
fnp-2955	66	13	key	key	ADJ
fnp-2955	66	14	upregulated	upregulated	ADJ
fnp-2955	66	15	(	(	PUNCT
fnp-2955	66	16	emilin2	emilin2	NOUN
fnp-2955	66	17	,	,	PUNCT
fnp-2955	66	18	col4a2	col4a2	NOUN
fnp-2955	66	19	,	,	PUNCT
fnp-2955	66	20	talin-1	talin-1	PROPN
fnp-2955	66	21	(	(	PUNCT
fnp-2955	66	22	tln1	tln1	PROPN
fnp-2955	66	23	)	)	PUNCT
fnp-2955	66	24	,	,	PUNCT
fnp-2955	66	25	clusterin	clusterin	NOUN
fnp-2955	66	26	(	(	PUNCT
fnp-2955	66	27	clu	clu	NOUN
fnp-2955	66	28	)	)	PUNCT
fnp-2955	66	29	)	)	PUNCT
fnp-2955	66	30	and	and	CCONJ
fnp-2955	66	31	downregulated	downregulate	VERB
fnp-2955	66	32	(	(	PUNCT
fnp-2955	66	33	desmoplakin	desmoplakin	X
fnp-2955	66	34	(	(	PUNCT
fnp-2955	66	35	dsp	dsp	NOUN
fnp-2955	66	36	)	)	PUNCT
fnp-2955	66	37	,	,	PUNCT
fnp-2955	66	38	insulin	insulin	NOUN
fnp-2955	66	39	-	-	PUNCT
fnp-2955	66	40	degrading	degrade	VERB
fnp-2955	66	41	enzyme	enzyme	NOUN
fnp-2955	66	42	(	(	PUNCT
fnp-2955	66	43	ide	ide	NOUN
fnp-2955	66	44	)	)	PUNCT
fnp-2955	66	45	,	,	PUNCT
fnp-2955	66	46	hemoglobin	hemoglobin	NOUN
fnp-2955	66	47	subunit	subunit	NOUN
fnp-2955	66	48	gamma-1	gamma-1	PROPN
fnp-2955	66	49	(	(	PUNCT
fnp-2955	66	50	hbg1	hbg1	PROPN
fnp-2955	66	51	)	)	PUNCT
fnp-2955	66	52	)	)	PUNCT
fnp-2955	66	53	proteins	protein	NOUN
fnp-2955	66	54	in	in	ADP
fnp-2955	66	55	the	the	DET
fnp-2955	66	56	white	white	ADJ
fnp-2955	66	57	matter	matter	NOUN
fnp-2955	66	58	of	of	ADP
fnp-2955	66	59	patients	patient	NOUN
fnp-2955	66	60	with	with	ADP
fnp-2955	66	61	caa	caa	PROPN
fnp-2955	66	62	vs.	vs.	ADP
fnp-2955	66	63	controls	control	NOUN
fnp-2955	66	64	(	(	PUNCT
fnp-2955	66	65	figure	figure	NOUN
fnp-2955	66	66	3	3	NUM
fnp-2955	66	67	)	)	PUNCT
fnp-2955	66	68	.	.	PUNCT
fnp-2955	67	1	figure	figure	VERB
fnp-2955	67	2	2	2	NUM
fnp-2955	67	3	:	:	PUNCT
fnp-2955	67	4	bioinformatics	bioinformatic	NOUN
fnp-2955	67	5	analysis	analysis	NOUN
fnp-2955	67	6	using	use	VERB
fnp-2955	67	7	metacore	metacore	ADV
fnp-2955	67	8	showed	show	VERB
fnp-2955	67	9	significant	significant	ADJ
fnp-2955	67	10	enrichment	enrichment	NOUN
fnp-2955	67	11	of	of	ADP
fnp-2955	67	12	the	the	DET
fnp-2955	67	13	cell	cell	NOUN
fnp-2955	67	14	-	-	PUNCT
fnp-2955	67	15	adhesion	adhesion	NOUN
fnp-2955	67	16	|	|	NOUN
fnp-2955	67	17	cell	cell	NOUN
fnp-2955	67	18	-	-	PUNCT
fnp-2955	67	19	matrix	matrix	NOUN
fnp-2955	67	20	interaction	interaction	NOUN
fnp-2955	67	21	processes	process	NOUN
fnp-2955	67	22	in	in	ADP
fnp-2955	67	23	the	the	DET
fnp-2955	67	24	differentially	differentially	ADV
fnp-2955	67	25	expressed	express	VERB
fnp-2955	67	26	proteins	protein	NOUN
fnp-2955	67	27	of	of	ADP
fnp-2955	67	28	white	white	ADJ
fnp-2955	67	29	matter	matter	NOUN
fnp-2955	67	30	from	from	ADP
fnp-2955	67	31	patients	patient	NOUN
fnp-2955	67	32	with	with	ADP
fnp-2955	67	33	caa	caa	PROPN
fnp-2955	67	34	vs.	vs.	ADP
fnp-2955	67	35	controls	control	NOUN
fnp-2955	67	36	.	.	PUNCT
fnp-2955	68	1	upregulated	upregulate	VERB
fnp-2955	68	2	proteins	protein	NOUN
fnp-2955	68	3	(	(	PUNCT
fnp-2955	68	4	emilin-2	emilin-2	NUM
fnp-2955	68	5	,	,	PUNCT
fnp-2955	68	6	fibrillin	fibrillin	PROPN
fnp-2955	68	7	,	,	PUNCT
fnp-2955	68	8	collagen	collagen	NOUN
fnp-2955	68	9	iv	iv	NUM
fnp-2955	68	10	,	,	PUNCT
fnp-2955	68	11	perlecan	perlecan	NUM
fnp-2955	68	12	)	)	PUNCT
fnp-2955	68	13	are	be	AUX
fnp-2955	68	14	highlighted	highlight	VERB
fnp-2955	68	15	with	with	ADP
fnp-2955	68	16	a	a	DET
fnp-2955	68	17	red	red	ADJ
fnp-2955	68	18	circle	circle	NOUN
fnp-2955	68	19	whereas	whereas	SCONJ
fnp-2955	68	20	downregulated	downregulate	VERB
fnp-2955	68	21	proteins	protein	NOUN
fnp-2955	68	22	(	(	PUNCT
fnp-2955	68	23	itih3	itih3	NOUN
fnp-2955	68	24	)	)	PUNCT
fnp-2955	68	25	with	with	ADP
fnp-2955	68	26	a	a	DET
fnp-2955	68	27	blue	blue	ADJ
fnp-2955	68	28	circle	circle	NOUN
fnp-2955	68	29	.	.	PUNCT
fnp-2955	69	1	the	the	DET
fnp-2955	69	2	p	p	NOUN
fnp-2955	69	3	represents	represent	VERB
fnp-2955	69	4	significance	significance	NOUN
fnp-2955	69	5	of	of	ADP
fnp-2955	69	6	enrichment	enrichment	NOUN
fnp-2955	69	7	(	(	PUNCT
fnp-2955	69	8	i.e.	i.e.	X
fnp-2955	69	9	this	this	DET
fnp-2955	69	10	pathway	pathway	NOUN
fnp-2955	69	11	is	be	AUX
fnp-2955	69	12	significantly	significantly	ADV
fnp-2955	69	13	enriched	enrich	VERB
fnp-2955	69	14	in	in	ADP
fnp-2955	69	15	the	the	DET
fnp-2955	69	16	list	list	NOUN
fnp-2955	69	17	of	of	ADP
fnp-2955	69	18	differentially	differentially	ADV
fnp-2955	69	19	expressed	express	VERB
fnp-2955	69	20	proteins	protein	NOUN
fnp-2955	69	21	)	)	PUNCT
fnp-2955	69	22	.	.	PUNCT
fnp-2955	70	1	figure	figure	VERB
fnp-2955	70	2	3	3	NUM
fnp-2955	70	3	:	:	PUNCT
fnp-2955	70	4	up	up	ADV
fnp-2955	70	5	-	-	PUNCT
fnp-2955	70	6	regulated	regulate	VERB
fnp-2955	70	7	(	(	PUNCT
fnp-2955	70	8	red	red	ADJ
fnp-2955	70	9	)	)	PUNCT
fnp-2955	70	10	and	and	CCONJ
fnp-2955	70	11	downregulated	downregulate	VERB
fnp-2955	70	12	(	(	PUNCT
fnp-2955	70	13	blue	blue	ADJ
fnp-2955	70	14	)	)	PUNCT
fnp-2955	70	15	proteins	protein	NOUN
fnp-2955	70	16	in	in	ADP
fnp-2955	70	17	white	white	ADJ
fnp-2955	70	18	matter	matter	NOUN
fnp-2955	70	19	from	from	ADP
fnp-2955	70	20	patients	patient	NOUN
fnp-2955	70	21	with	with	ADP
fnp-2955	70	22	caa	caa	PROPN
fnp-2955	70	23	vs.	vs.	ADP
fnp-2955	70	24	controls	control	NOUN
fnp-2955	70	25	.	.	PUNCT
fnp-2955	71	1	a	a	DET
fnp-2955	71	2	positive	positive	ADJ
fnp-2955	71	3	log2ratio	log2ratio	PROPN
fnp-2955	71	4	(	(	PUNCT
fnp-2955	71	5	ratio>1	ratio>1	NOUN
fnp-2955	71	6	)	)	PUNCT
fnp-2955	71	7	reflects	reflect	VERB
fnp-2955	71	8	upwhereas	upwhereas	ADJ
fnp-2955	71	9	a	a	DET
fnp-2955	71	10	negative	negative	ADJ
fnp-2955	71	11	log2ratio	log2ratio	PROPN
fnp-2955	71	12	(	(	PUNCT
fnp-2955	71	13	ratio<1	ratio<1	NOUN
fnp-2955	71	14	)	)	PUNCT
fnp-2955	71	15	reflects	reflect	VERB
fnp-2955	71	16	downregulation	downregulation	NOUN
fnp-2955	71	17	of	of	ADP
fnp-2955	71	18	the	the	DET
fnp-2955	71	19	respective	respective	ADJ
fnp-2955	71	20	protein	protein	NOUN
fnp-2955	71	21	in	in	ADP
fnp-2955	71	22	patients	patient	NOUN
fnp-2955	71	23	with	with	ADP
fnp-2955	71	24	caa	caa	PROPN
fnp-2955	71	25	vs.	vs.	ADP
fnp-2955	71	26	controls	control	NOUN
fnp-2955	71	27	.	.	PUNCT
fnp-2955	72	1	metacore	metacore	ADJ
fnp-2955	72	2	demonstrated	demonstrate	VERB
fnp-2955	72	3	dysregulation	dysregulation	NOUN
fnp-2955	72	4	of	of	ADP
fnp-2955	72	5	the	the	DET
fnp-2955	72	6	hypoxia	hypoxia	NOUN
fnp-2955	72	7	-	-	PUNCT
fnp-2955	72	8	inducible	inducible	ADJ
fnp-2955	72	9	factor	factor	NOUN
fnp-2955	72	10	1alpha	1alpha	NUM
fnp-2955	72	11	(	(	PUNCT
fnp-2955	72	12	hif1a	hif1a	PROPN
fnp-2955	72	13	)	)	PUNCT
fnp-2955	72	14	in	in	ADP
fnp-2955	72	15	caa	caa	NOUN
fnp-2955	72	16	with	with	ADP
fnp-2955	72	17	upregulation	upregulation	NOUN
fnp-2955	72	18	of	of	ADP
fnp-2955	72	19	diamine	diamine	ADJ
fnp-2955	72	20	acetyltransferase	acetyltransferase	NOUN
fnp-2955	72	21	2	2	NUM
fnp-2955	72	22	(	(	PUNCT
fnp-2955	72	23	sat2	sat2	PROPN
fnp-2955	72	24	)	)	PUNCT
fnp-2955	72	25	and	and	CCONJ
fnp-2955	72	26	downregulation	downregulation	NOUN
fnp-2955	72	27	of	of	ADP
fnp-2955	72	28	heat	heat	NOUN
fnp-2955	72	29	shock	shock	NOUN
fnp-2955	72	30	70kda	70kda	NUM
fnp-2955	72	31	protein	protein	NOUN
fnp-2955	72	32	4	4	NUM
fnp-2955	72	33	(	(	PUNCT
fnp-2955	72	34	hspa4	hspa4	PROPN
fnp-2955	72	35	)	)	PUNCT
fnp-2955	72	36	,	,	PUNCT
fnp-2955	72	37	heat	heat	NOUN
fnp-2955	72	38	shock	shock	NOUN
fnp-2955	72	39	70kda	70kda	NUM
fnp-2955	72	40	protein	protein	NOUN
fnp-2955	72	41	1a/1b	1a/1b	NUM
fnp-2955	72	42	(	(	PUNCT
fnp-2955	72	43	hspa1a	hspa1a	PROPN
fnp-2955	72	44	)	)	PUNCT
fnp-2955	72	45	,	,	PUNCT
fnp-2955	72	46	78kda	78kda	NOUN
fnp-2955	72	47	glucose	glucose	NOUN
fnp-2955	72	48	-	-	PUNCT
fnp-2955	72	49	related	relate	VERB
fnp-2955	72	50	protein	protein	NOUN
fnp-2955	72	51	(	(	PUNCT
fnp-2955	72	52	hspa5	hspa5	ADJ
fnp-2955	72	53	)	)	PUNCT
fnp-2955	72	54	,	,	PUNCT
fnp-2955	72	55	endoplasmin	endoplasmin	NOUN
fnp-2955	72	56	(	(	PUNCT
fnp-2955	72	57	hsp90b1	hsp90b1	PROPN
fnp-2955	72	58	)	)	PUNCT
fnp-2955	72	59	,	,	PUNCT
fnp-2955	72	60	transitional	transitional	ADJ
fnp-2955	72	61	endoplasmic	endoplasmic	ADJ
fnp-2955	72	62	reticulum	reticulum	NOUN
fnp-2955	72	63	atpase	atpase	NOUN
fnp-2955	72	64	(	(	PUNCT
fnp-2955	72	65	vcp	vcp	NOUN
fnp-2955	72	66	)	)	PUNCT
fnp-2955	72	67	and	and	CCONJ
fnp-2955	72	68	guanine	guanine	NOUN
fnp-2955	72	69	nucleotide	nucleotide	NOUN
fnp-2955	72	70	binding	bind	VERB
fnp-2955	72	71	protein	protein	NOUN
fnp-2955	72	72	subunit	subunit	NOUN
fnp-2955	72	73	beta-2	beta-2	PROPN
fnp-2955	72	74	-	-	PUNCT
fnp-2955	72	75	like-1	like-1	PROPN
fnp-2955	72	76	(	(	PUNCT
fnp-2955	72	77	gnb2l1	gnb2l1	NOUN
fnp-2955	72	78	)	)	PUNCT
fnp-2955	72	79	,	,	PUNCT
fnp-2955	72	80	suggesting	suggest	VERB
fnp-2955	72	81	altered	altered	ADJ
fnp-2955	72	82	response	response	NOUN
fnp-2955	72	83	to	to	PART
fnp-2955	72	84	hypoxia	hypoxia	VERB
fnp-2955	72	85	in	in	ADP
fnp-2955	72	86	caa	caa	NOUN
fnp-2955	72	87	(	(	PUNCT
fnp-2955	72	88	figure	figure	NOUN
fnp-2955	72	89	4	4	NUM
fnp-2955	72	90	)	)	PUNCT
fnp-2955	72	91	.	.	PUNCT
fnp-2955	73	1	figure	figure	VERB
fnp-2955	73	2	4	4	NUM
fnp-2955	73	3	:	:	PUNCT
fnp-2955	73	4	negative	negative	ADJ
fnp-2955	73	5	regulation	regulation	NOUN
fnp-2955	73	6	of	of	ADP
fnp-2955	73	7	hif1a	hif1a	PROPN
fnp-2955	73	8	was	be	AUX
fnp-2955	73	9	a	a	DET
fnp-2955	73	10	significantly	significantly	ADV
fnp-2955	73	11	enriched	enrich	VERB
fnp-2955	73	12	pathway	pathway	NOUN
fnp-2955	73	13	map	map	NOUN
fnp-2955	73	14	in	in	ADP
fnp-2955	73	15	the	the	DET
fnp-2955	73	16	differentially	differentially	ADV
fnp-2955	73	17	expressed	express	VERB
fnp-2955	73	18	proteins	protein	NOUN
fnp-2955	73	19	of	of	ADP
fnp-2955	73	20	white	white	ADJ
fnp-2955	73	21	matter	matter	NOUN
fnp-2955	73	22	from	from	ADP
fnp-2955	73	23	patients	patient	NOUN
fnp-2955	73	24	with	with	ADP
fnp-2955	73	25	caa	caa	PROPN
fnp-2955	73	26	vs.	vs.	ADP
fnp-2955	73	27	controls	control	NOUN
fnp-2955	73	28	.	.	PUNCT
fnp-2955	74	1	upregulated	upregulate	VERB
fnp-2955	74	2	proteins	protein	NOUN
fnp-2955	74	3	are	be	AUX
fnp-2955	74	4	highlighted	highlight	VERB
fnp-2955	74	5	with	with	ADP
fnp-2955	74	6	a	a	DET
fnp-2955	74	7	red	red	ADJ
fnp-2955	74	8	circle	circle	NOUN
fnp-2955	74	9	whereas	whereas	SCONJ
fnp-2955	74	10	downregulated	downregulate	VERB
fnp-2955	74	11	proteins	protein	NOUN
fnp-2955	74	12	with	with	ADP
fnp-2955	74	13	a	a	DET
fnp-2955	74	14	blue	blue	ADJ
fnp-2955	74	15	circle	circle	NOUN
fnp-2955	74	16	.	.	PUNCT
fnp-2955	75	1	more	more	ADV
fnp-2955	75	2	specifically	specifically	ADV
fnp-2955	75	3	,	,	PUNCT
fnp-2955	75	4	sat2	sat2	PROPN
fnp-2955	75	5	was	be	AUX
fnp-2955	75	6	upregulated	upregulate	VERB
fnp-2955	75	7	whereas	whereas	SCONJ
fnp-2955	75	8	hsp70	hsp70	NOUN
fnp-2955	75	9	,	,	PUNCT
fnp-2955	75	10	hspa4	hspa4	NOUN
fnp-2955	75	11	,	,	PUNCT
fnp-2955	75	12	hsp90	hsp90	NOUN
fnp-2955	75	13	,	,	PUNCT
fnp-2955	75	14	rack1	rack1	NOUN
fnp-2955	75	15	were	be	AUX
fnp-2955	75	16	downregulated	downregulate	VERB
fnp-2955	75	17	in	in	ADP
fnp-2955	75	18	caa	caa	NOUN
fnp-2955	75	19	vs.	vs.	ADP
fnp-2955	75	20	control	control	NOUN
fnp-2955	75	21	.	.	PUNCT
fnp-2955	76	1	the	the	DET
fnp-2955	76	2	p	p	NOUN
fnp-2955	76	3	represents	represent	VERB
fnp-2955	76	4	significance	significance	NOUN
fnp-2955	76	5	of	of	ADP
fnp-2955	76	6	enrichment	enrichment	NOUN
fnp-2955	76	7	(	(	PUNCT
fnp-2955	76	8	i.e.	i.e.	X
fnp-2955	76	9	this	this	DET
fnp-2955	76	10	pathway	pathway	NOUN
fnp-2955	76	11	is	be	AUX
fnp-2955	76	12	significantly	significantly	ADV
fnp-2955	76	13	enriched	enrich	VERB
fnp-2955	76	14	in	in	ADP
fnp-2955	76	15	the	the	DET
fnp-2955	76	16	list	list	NOUN
fnp-2955	76	17	of	of	ADP
fnp-2955	76	18	differentially	differentially	ADV
fnp-2955	76	19	expressed	express	VERB
fnp-2955	76	20	proteins	protein	NOUN
fnp-2955	76	21	)	)	PUNCT
fnp-2955	76	22	.	.	PUNCT
fnp-2955	77	1	mitochondrial	mitochondrial	ADJ
fnp-2955	77	2	function	function	NOUN
fnp-2955	77	3	also	also	ADV
fnp-2955	77	4	appeared	appear	VERB
fnp-2955	77	5	altered	alter	VERB
fnp-2955	77	6	in	in	ADP
fnp-2955	77	7	caa	caa	NOUN
fnp-2955	77	8	with	with	ADP
fnp-2955	77	9	upregulation	upregulation	NOUN
fnp-2955	77	10	of	of	ADP
fnp-2955	77	11	the	the	DET
fnp-2955	77	12	mitochondrial	mitochondrial	ADJ
fnp-2955	77	13	fission	fission	NOUN
fnp-2955	77	14	1	1	NUM
fnp-2955	77	15	protein	protein	NOUN
fnp-2955	77	16	(	(	PUNCT
fnp-2955	77	17	fis1	fis1	PROPN
fnp-2955	77	18	)	)	PUNCT
fnp-2955	77	19	,	,	PUNCT
fnp-2955	77	20	a	a	DET
fnp-2955	77	21	marker	marker	NOUN
fnp-2955	77	22	of	of	ADP
fnp-2955	77	23	mitochondrial	mitochondrial	ADJ
fnp-2955	77	24	and	and	CCONJ
fnp-2955	77	25	mitophagy	mitophagy	NOUN
fnp-2955	77	26	(	(	PUNCT
fnp-2955	77	27	21	21	NUM
fnp-2955	77	28	)	)	PUNCT
fnp-2955	77	29	and	and	CCONJ
fnp-2955	77	30	reductions	reduction	NOUN
fnp-2955	77	31	in	in	ADP
fnp-2955	77	32	proteins	protein	NOUN
fnp-2955	77	33	associated	associate	VERB
fnp-2955	77	34	with	with	ADP
fnp-2955	77	35	the	the	DET
fnp-2955	77	36	normal	normal	ADJ
fnp-2955	77	37	function	function	NOUN
fnp-2955	77	38	of	of	ADP
fnp-2955	77	39	the	the	DET
fnp-2955	77	40	mitochondria	mitochondria	NOUN
fnp-2955	77	41	(	(	PUNCT
fnp-2955	77	42	mitochondrial	mitochondrial	ADJ
fnp-2955	77	43	succinate	succinate	NOUN
fnp-2955	77	44	dehydrogenase	dehydrogenase	NOUN
fnp-2955	77	45	flavoprotein	flavoprotein	ADJ
fnp-2955	77	46	subunit	subunit	NOUN
fnp-2955	77	47	(	(	PUNCT
fnp-2955	77	48	sdha	sdha	NOUN
fnp-2955	77	49	)	)	PUNCT
fnp-2955	77	50	,	,	PUNCT
fnp-2955	77	51	mitochondrial	mitochondrial	ADJ
fnp-2955	77	52	aconitate	aconitate	NOUN
fnp-2955	77	53	hydratase	hydratase	PROPN
fnp-2955	77	54	(	(	PUNCT
fnp-2955	77	55	aco2	aco2	PROPN
fnp-2955	77	56	)	)	PUNCT
fnp-2955	77	57	,	,	PUNCT
fnp-2955	77	58	mitochondrial	mitochondrial	ADJ
fnp-2955	77	59	phospholipid	phospholipid	NOUN
fnp-2955	77	60	hydroperoxide	hydroperoxide	ADP
fnp-2955	77	61	glutathione	glutathione	NOUN
fnp-2955	77	62	peroxidase	peroxidase	NOUN
fnp-2955	77	63	(	(	PUNCT
fnp-2955	77	64	gpx4	gpx4	PROPN
fnp-2955	77	65	)	)	PUNCT
fnp-2955	77	66	,	,	PUNCT
fnp-2955	77	67	mitochondrial	mitochondrial	ADJ
fnp-2955	77	68	atp	atp	NOUN
fnp-2955	77	69	synthase	synthase	NOUN
fnp-2955	77	70	subunit	subunit	NOUN
fnp-2955	77	71	beta	beta	NOUN
fnp-2955	77	72	(	(	PUNCT
fnp-2955	77	73	atp5f1b	atp5f1b	PROPN
fnp-2955	77	74	)	)	PUNCT
fnp-2955	77	75	,	,	PUNCT
fnp-2955	77	76	mitochondrial	mitochondrial	ADJ
fnp-2955	77	77	thioredoxin	thioredoxin	PROPN
fnp-2955	77	78	reductase	reductase	NOUN
fnp-2955	77	79	2	2	NUM
fnp-2955	77	80	(	(	PUNCT
fnp-2955	77	81	txnrd2	txnrd2	NOUN
fnp-2955	77	82	)	)	PUNCT
fnp-2955	77	83	,	,	PUNCT
fnp-2955	77	84	mitogen	mitogen	NOUN
fnp-2955	77	85	-	-	PUNCT
fnp-2955	77	86	activated	activate	VERB
fnp-2955	77	87	protein	protein	NOUN
fnp-2955	77	88	kinase	kinase	NOUN
fnp-2955	77	89	9	9	NUM
fnp-2955	77	90	(	(	PUNCT
fnp-2955	77	91	mapk9	mapk9	PROPN
fnp-2955	77	92	)	)	PUNCT
fnp-2955	77	93	)	)	PUNCT
fnp-2955	77	94	.	.	PUNCT
fnp-2955	78	1	mitochondrial	mitochondrial	ADJ
fnp-2955	78	2	dysfunction	dysfunction	NOUN
fnp-2955	78	3	was	be	AUX
fnp-2955	78	4	a	a	DET
fnp-2955	78	5	significantly	significantly	ADV
fnp-2955	78	6	over	over	ADV
fnp-2955	78	7	-	-	PUNCT
fnp-2955	78	8	represented	represent	VERB
fnp-2955	78	9	canonical	canonical	ADJ
fnp-2955	78	10	pathway	pathway	NOUN
fnp-2955	78	11	(	(	PUNCT
fnp-2955	78	12	figure	figure	NOUN
fnp-2955	78	13	5	5	NUM
fnp-2955	78	14	)	)	PUNCT
fnp-2955	78	15	.	.	PUNCT
fnp-2955	79	1	figure	figure	VERB
fnp-2955	79	2	5	5	NUM
fnp-2955	79	3	:	:	PUNCT
fnp-2955	79	4	mitochondrial	mitochondrial	ADJ
fnp-2955	79	5	dysfunction	dysfunction	NOUN
fnp-2955	79	6	was	be	AUX
fnp-2955	79	7	a	a	DET
fnp-2955	79	8	significantly	significantly	ADV
fnp-2955	79	9	enriched	enrich	VERB
fnp-2955	79	10	canonical	canonical	ADJ
fnp-2955	79	11	pathway	pathway	NOUN
fnp-2955	79	12	in	in	ADP
fnp-2955	79	13	the	the	DET
fnp-2955	79	14	differentially	differentially	ADV
fnp-2955	79	15	expressed	express	VERB
fnp-2955	79	16	proteins	protein	NOUN
fnp-2955	79	17	of	of	ADP
fnp-2955	79	18	white	white	ADJ
fnp-2955	79	19	matter	matter	NOUN
fnp-2955	79	20	from	from	ADP
fnp-2955	79	21	patients	patient	NOUN
fnp-2955	79	22	with	with	ADP
fnp-2955	79	23	caa	caa	PROPN
fnp-2955	79	24	vs.	vs.	ADP
fnp-2955	79	25	controls	control	NOUN
fnp-2955	79	26	.	.	PUNCT
fnp-2955	80	1	upregulated	upregulate	VERB
fnp-2955	80	2	proteins	protein	NOUN
fnp-2955	80	3	are	be	AUX
fnp-2955	80	4	denoted	denote	VERB
fnp-2955	80	5	with	with	ADP
fnp-2955	80	6	red	red	ADJ
fnp-2955	80	7	whereas	whereas	SCONJ
fnp-2955	80	8	downregulated	downregulate	VERB
fnp-2955	80	9	proteins	protein	NOUN
fnp-2955	80	10	with	with	ADP
fnp-2955	80	11	blue	blue	ADJ
fnp-2955	80	12	.	.	PUNCT
fnp-2955	81	1	more	more	ADV
fnp-2955	81	2	specifically	specifically	ADV
fnp-2955	81	3	,	,	PUNCT
fnp-2955	81	4	fis1	fis1	PROPN
fnp-2955	81	5	was	be	AUX
fnp-2955	81	6	upregulated	upregulate	VERB
fnp-2955	81	7	whereas	whereas	SCONJ
fnp-2955	81	8	sdha	sdha	NOUN
fnp-2955	81	9	,	,	PUNCT
fnp-2955	81	10	aco2	aco2	NOUN
fnp-2955	81	11	,	,	PUNCT
fnp-2955	81	12	gpx4	gpx4	PROPN
fnp-2955	81	13	,	,	PUNCT
fnp-2955	81	14	atp5f1b	atp5f1b	PROPN
fnp-2955	81	15	,	,	PUNCT
fnp-2955	81	16	txnrd2	txnrd2	NOUN
fnp-2955	81	17	and	and	CCONJ
fnp-2955	81	18	mapk9	mapk9	NOUN
fnp-2955	81	19	were	be	AUX
fnp-2955	81	20	downregulated	downregulate	VERB
fnp-2955	81	21	in	in	ADP
fnp-2955	81	22	caa	caa	NOUN
fnp-2955	81	23	vs.	vs.	ADP
fnp-2955	81	24	control	control	NOUN
fnp-2955	81	25	.	.	PUNCT
fnp-2955	82	1	the	the	DET
fnp-2955	82	2	p	p	NOUN
fnp-2955	82	3	represents	represent	VERB
fnp-2955	82	4	significance	significance	NOUN
fnp-2955	82	5	of	of	ADP
fnp-2955	82	6	enrichment	enrichment	NOUN
fnp-2955	82	7	(	(	PUNCT
fnp-2955	82	8	i.e.	i.e.	X
fnp-2955	82	9	this	this	DET
fnp-2955	82	10	pathway	pathway	NOUN
fnp-2955	82	11	is	be	AUX
fnp-2955	82	12	significantly	significantly	ADV
fnp-2955	82	13	enriched	enrich	VERB
fnp-2955	82	14	in	in	ADP
fnp-2955	82	15	the	the	DET
fnp-2955	82	16	list	list	NOUN
fnp-2955	82	17	of	of	ADP
fnp-2955	82	18	differentially	differentially	ADV
fnp-2955	82	19	expressed	express	VERB
fnp-2955	82	20	proteins	protein	NOUN
fnp-2955	82	21	)	)	PUNCT
fnp-2955	82	22	.	.	PUNCT
fnp-2955	83	1	discussion	discussion	NOUN
fnp-2955	83	2	the	the	DET
fnp-2955	83	3	present	present	ADJ
fnp-2955	83	4	study	study	NOUN
fnp-2955	83	5	reports	report	VERB
fnp-2955	83	6	a	a	DET
fnp-2955	83	7	comprehensive	comprehensive	ADJ
fnp-2955	83	8	global	global	ADJ
fnp-2955	83	9	proteomic	proteomic	ADJ
fnp-2955	83	10	profile	profile	NOUN
fnp-2955	83	11	of	of	ADP
fnp-2955	83	12	post	post	ADJ
fnp-2955	83	13	-	-	ADJ
fnp-2955	83	14	mortem	mortem	ADJ
fnp-2955	83	15	white	white	ADJ
fnp-2955	83	16	matter	matter	NOUN
fnp-2955	83	17	samples	sample	NOUN
fnp-2955	83	18	from	from	ADP
fnp-2955	83	19	patients	patient	NOUN
fnp-2955	83	20	with	with	ADP
fnp-2955	83	21	caa	caa	NOUN
fnp-2955	83	22	compared	compare	VERB
fnp-2955	83	23	to	to	ADP
fnp-2955	83	24	the	the	DET
fnp-2955	83	25	corresponding	correspond	VERB
fnp-2955	83	26	brain	brain	NOUN
fnp-2955	83	27	region	region	NOUN
fnp-2955	83	28	of	of	ADP
fnp-2955	83	29	age	age	NOUN
fnp-2955	83	30	-	-	PUNCT
fnp-2955	83	31	matched	match	VERB
fnp-2955	83	32	controls	control	NOUN
fnp-2955	83	33	.	.	PUNCT
fnp-2955	84	1	out	out	ADP
fnp-2955	84	2	of	of	ADP
fnp-2955	84	3	189	189	NUM
fnp-2955	84	4	proteins	protein	NOUN
fnp-2955	84	5	identified	identify	VERB
fnp-2955	84	6	as	as	SCONJ
fnp-2955	84	7	differentially	differentially	ADV
fnp-2955	84	8	expressed	express	VERB
fnp-2955	84	9	with	with	ADP
fnp-2955	84	10	both	both	CCONJ
fnp-2955	84	11	metacore	metacore	ADJ
fnp-2955	84	12	and	and	CCONJ
fnp-2955	84	13	ipa	ipa	PROPN
fnp-2955	84	14	,	,	PUNCT
fnp-2955	84	15	several	several	ADJ
fnp-2955	84	16	proteins	protein	NOUN
fnp-2955	84	17	associated	associate	VERB
fnp-2955	84	18	with	with	ADP
fnp-2955	84	19	mitochondrial	mitochondrial	ADJ
fnp-2955	84	20	dysfunction	dysfunction	NOUN
fnp-2955	84	21	,	,	PUNCT
fnp-2955	84	22	hypoxia	hypoxia	NOUN
fnp-2955	84	23	,	,	PUNCT
fnp-2955	84	24	and	and	CCONJ
fnp-2955	84	25	clearance	clearance	NOUN
fnp-2955	84	26	of	of	ADP
fnp-2955	84	27	aβ	aβ	NOUN
fnp-2955	84	28	are	be	AUX
fnp-2955	84	29	significantly	significantly	ADV
fnp-2955	84	30	upor	upor	ADJ
fnp-2955	84	31	downregulated	downregulate	VERB
fnp-2955	84	32	.	.	PUNCT
fnp-2955	85	1	the	the	DET
fnp-2955	85	2	pathways	pathway	NOUN
fnp-2955	85	3	reflecting	reflect	VERB
fnp-2955	85	4	hypoxia	hypoxia	NOUN
fnp-2955	85	5	and	and	CCONJ
fnp-2955	85	6	mitochondrial	mitochondrial	ADJ
fnp-2955	85	7	dysfunction	dysfunction	NOUN
fnp-2955	85	8	have	have	AUX
fnp-2955	85	9	been	be	AUX
fnp-2955	85	10	observed	observe	VERB
fnp-2955	85	11	in	in	ADP
fnp-2955	85	12	previous	previous	ADJ
fnp-2955	85	13	analyses	analysis	NOUN
fnp-2955	85	14	of	of	ADP
fnp-2955	85	15	the	the	DET
fnp-2955	85	16	white	white	ADJ
fnp-2955	85	17	matter	matter	NOUN
fnp-2955	85	18	in	in	ADP
fnp-2955	85	19	alzheimer	alzheimer	PROPN
fnp-2955	85	20	’s	’s	PART
fnp-2955	85	21	disease	disease	NOUN
fnp-2955	85	22	(	(	PUNCT
fnp-2955	85	23	22	22	NUM
fnp-2955	85	24	)	)	PUNCT
fnp-2955	85	25	.	.	PUNCT
fnp-2955	86	1	hypoxia	hypoxia	NOUN
fnp-2955	86	2	-	-	PUNCT
fnp-2955	86	3	inducible	inducible	ADJ
fnp-2955	86	4	factor-1	factor-1	PROPN
fnp-2955	86	5	(	(	PUNCT
fnp-2955	86	6	hif1	hif1	PROPN
fnp-2955	86	7	)	)	PUNCT
fnp-2955	86	8	regulates	regulate	VERB
fnp-2955	86	9	oxygen	oxygen	NOUN
fnp-2955	86	10	homeostasis	homeostasis	NOUN
fnp-2955	86	11	and	and	CCONJ
fnp-2955	86	12	thus	thus	ADV
fnp-2955	86	13	has	have	VERB
fnp-2955	86	14	a	a	DET
fnp-2955	86	15	major	major	ADJ
fnp-2955	86	16	role	role	NOUN
fnp-2955	86	17	in	in	ADP
fnp-2955	86	18	the	the	DET
fnp-2955	86	19	control	control	NOUN
fnp-2955	86	20	of	of	ADP
fnp-2955	86	21	energy	energy	NOUN
fnp-2955	86	22	/	/	SYM
fnp-2955	86	23	metabolism	metabolism	NOUN
fnp-2955	86	24	and	and	CCONJ
fnp-2955	86	25	angiogenesis	angiogenesis	NOUN
fnp-2955	86	26	.	.	PUNCT
fnp-2955	87	1	diamine	diamine	NOUN
fnp-2955	87	2	-	-	PUNCT
fnp-2955	87	3	acetyltransferase-2	acetyltransferase-2	PROPN
fnp-2955	87	4	(	(	PUNCT
fnp-2955	87	5	sat2	sat2	PROPN
fnp-2955	87	6	)	)	PUNCT
fnp-2955	87	7	,	,	PUNCT
fnp-2955	87	8	guanine	guanine	NOUN
fnp-2955	87	9	nucleotide	nucleotide	NOUN
fnp-2955	87	10	binding	bind	VERB
fnp-2955	87	11	protein	protein	NOUN
fnp-2955	87	12	subunit	subunit	NOUN
fnp-2955	87	13	beta-2	beta-2	NOUN
fnp-2955	87	14	-	-	PUNCT
fnp-2955	87	15	like	like	ADJ
fnp-2955	87	16	1	1	NUM
fnp-2955	87	17	(	(	PUNCT
fnp-2955	87	18	gnb2l1	gnb2l1	NOUN
fnp-2955	87	19	)	)	PUNCT
fnp-2955	87	20	and	and	CCONJ
fnp-2955	87	21	heat	heat	NOUN
fnp-2955	87	22	shock	shock	NOUN
fnp-2955	87	23	proteins	protein	NOUN
fnp-2955	87	24	are	be	AUX
fnp-2955	87	25	involved	involve	VERB
fnp-2955	87	26	in	in	ADP
fnp-2955	87	27	the	the	DET
fnp-2955	87	28	degradation	degradation	NOUN
fnp-2955	87	29	of	of	ADP
fnp-2955	87	30	hif1	hif1	PROPN
fnp-2955	87	31	(	(	PUNCT
fnp-2955	87	32	23	23	NUM
fnp-2955	87	33	,	,	PUNCT
fnp-2955	87	34	24	24	NUM
fnp-2955	87	35	)	)	PUNCT
fnp-2955	87	36	and	and	CCONJ
fnp-2955	87	37	they	they	PRON
fnp-2955	87	38	were	be	AUX
fnp-2955	87	39	expressed	express	VERB
fnp-2955	87	40	at	at	ADP
fnp-2955	87	41	altered	altered	ADJ
fnp-2955	87	42	levels	level	NOUN
fnp-2955	87	43	in	in	ADP
fnp-2955	87	44	the	the	DET
fnp-2955	87	45	white	white	ADJ
fnp-2955	87	46	matter	matter	NOUN
fnp-2955	87	47	of	of	ADP
fnp-2955	87	48	caa	caa	NOUN
fnp-2955	87	49	cases	case	NOUN
fnp-2955	87	50	(	(	PUNCT
fnp-2955	87	51	figure	figure	NOUN
fnp-2955	87	52	4	4	NUM
fnp-2955	87	53	)	)	PUNCT
fnp-2955	87	54	.	.	PUNCT
fnp-2955	88	1	in	in	ADP
fnp-2955	88	2	the	the	DET
fnp-2955	88	3	present	present	ADJ
fnp-2955	88	4	study	study	NOUN
fnp-2955	88	5	there	there	PRON
fnp-2955	88	6	was	be	VERB
fnp-2955	88	7	an	an	DET
fnp-2955	88	8	increase	increase	NOUN
fnp-2955	88	9	in	in	ADP
fnp-2955	88	10	fis1	fis1	PROPN
fnp-2955	88	11	,	,	PUNCT
fnp-2955	88	12	a	a	DET
fnp-2955	88	13	marker	marker	NOUN
fnp-2955	88	14	of	of	ADP
fnp-2955	88	15	mitochondrial	mitochondrial	ADJ
fnp-2955	88	16	and	and	CCONJ
fnp-2955	88	17	mitophagy	mitophagy	NOUN
fnp-2955	88	18	(	(	PUNCT
fnp-2955	88	19	21	21	NUM
fnp-2955	88	20	)	)	PUNCT
fnp-2955	88	21	,	,	PUNCT
fnp-2955	88	22	and	and	CCONJ
fnp-2955	88	23	a	a	DET
fnp-2955	88	24	reduction	reduction	NOUN
fnp-2955	88	25	in	in	ADP
fnp-2955	88	26	proteins	protein	NOUN
fnp-2955	88	27	associated	associate	VERB
fnp-2955	88	28	with	with	ADP
fnp-2955	88	29	the	the	DET
fnp-2955	88	30	normal	normal	ADJ
fnp-2955	88	31	function	function	NOUN
fnp-2955	88	32	of	of	ADP
fnp-2955	88	33	the	the	DET
fnp-2955	88	34	mitochondria	mitochondria	NOUN
fnp-2955	88	35	(	(	PUNCT
fnp-2955	88	36	sdha	sdha	PROPN
fnp-2955	88	37	,	,	PUNCT
fnp-2955	88	38	aco2	aco2	NOUN
fnp-2955	88	39	,	,	PUNCT
fnp-2955	88	40	gpx4	gpx4	PROPN
fnp-2955	88	41	,	,	PUNCT
fnp-2955	88	42	atp5f1b	atp5f1b	PROPN
fnp-2955	88	43	,	,	PUNCT
fnp-2955	88	44	txnrd2	txnrd2	NOUN
fnp-2955	88	45	,	,	PUNCT
fnp-2955	88	46	mapk9	mapk9	PROPN
fnp-2955	88	47	)	)	PUNCT
fnp-2955	88	48	,	,	PUNCT
fnp-2955	88	49	suggesting	suggest	VERB
fnp-2955	88	50	an	an	DET
fnp-2955	88	51	overall	overall	ADJ
fnp-2955	88	52	dysregulation	dysregulation	NOUN
fnp-2955	88	53	of	of	ADP
fnp-2955	88	54	the	the	DET
fnp-2955	88	55	functions	function	NOUN
fnp-2955	88	56	of	of	ADP
fnp-2955	88	57	the	the	DET
fnp-2955	88	58	mitochondria	mitochondria	NOUN
fnp-2955	88	59	in	in	ADP
fnp-2955	88	60	the	the	DET
fnp-2955	88	61	white	white	ADJ
fnp-2955	88	62	matter	matter	NOUN
fnp-2955	88	63	from	from	ADP
fnp-2955	88	64	cases	case	NOUN
fnp-2955	88	65	of	of	ADP
fnp-2955	88	66	caa	caa	NOUN
fnp-2955	88	67	(	(	PUNCT
fnp-2955	88	68	figure	figure	NOUN
fnp-2955	88	69	5	5	NUM
fnp-2955	88	70	)	)	PUNCT
fnp-2955	88	71	.	.	PUNCT
fnp-2955	89	1	most	most	ADJ
fnp-2955	89	2	of	of	ADP
fnp-2955	89	3	the	the	DET
fnp-2955	89	4	novel	novel	ADJ
fnp-2955	89	5	proteins	protein	NOUN
fnp-2955	89	6	showing	show	VERB
fnp-2955	89	7	substantial	substantial	ADJ
fnp-2955	89	8	changes	change	NOUN
fnp-2955	89	9	in	in	ADP
fnp-2955	89	10	the	the	DET
fnp-2955	89	11	present	present	ADJ
fnp-2955	89	12	study	study	NOUN
fnp-2955	89	13	of	of	ADP
fnp-2955	89	14	the	the	DET
fnp-2955	89	15	white	white	ADJ
fnp-2955	89	16	matter	matter	NOUN
fnp-2955	89	17	in	in	ADP
fnp-2955	89	18	caa	caa	NOUN
fnp-2955	89	19	were	be	AUX
fnp-2955	89	20	proteins	protein	NOUN
fnp-2955	89	21	associated	associate	VERB
fnp-2955	89	22	with	with	ADP
fnp-2955	89	23	the	the	DET
fnp-2955	89	24	extracellular	extracellular	ADJ
fnp-2955	89	25	matrix	matrix	NOUN
fnp-2955	89	26	constituents	constituent	NOUN
fnp-2955	89	27	and	and	CCONJ
fnp-2955	89	28	clearance	clearance	NOUN
fnp-2955	89	29	of	of	ADP
fnp-2955	89	30	aβ	aβ	NOUN
fnp-2955	89	31	.	.	NOUN
fnp-2955	89	32	proteins	protein	NOUN
fnp-2955	89	33	with	with	ADP
fnp-2955	89	34	increased	increase	VERB
fnp-2955	89	35	expression	expression	NOUN
fnp-2955	89	36	collagen	collagen	NOUN
fnp-2955	89	37	iv	iv	NUM
fnp-2955	89	38	alpha	alpha	NOUN
fnp-2955	89	39	2	2	NUM
fnp-2955	89	40	chain	chain	NOUN
fnp-2955	89	41	(	(	PUNCT
fnp-2955	89	42	col4a2	col4a2	PROPN
fnp-2955	89	43	)	)	PUNCT
fnp-2955	89	44	is	be	AUX
fnp-2955	89	45	a	a	DET
fnp-2955	89	46	highly	highly	ADV
fnp-2955	89	47	conserved	conserved	ADJ
fnp-2955	89	48	protein	protein	NOUN
fnp-2955	89	49	across	across	ADP
fnp-2955	89	50	species	specie	NOUN
fnp-2955	89	51	and	and	CCONJ
fnp-2955	89	52	is	be	AUX
fnp-2955	89	53	present	present	ADJ
fnp-2955	89	54	in	in	ADP
fnp-2955	89	55	almost	almost	ADV
fnp-2955	89	56	all	all	PRON
fnp-2955	89	57	vascular	vascular	ADJ
fnp-2955	89	58	basement	basement	NOUN
fnp-2955	89	59	membranes	membrane	NOUN
fnp-2955	89	60	(	(	PUNCT
fnp-2955	89	61	bm	bm	PROPN
fnp-2955	89	62	)	)	PUNCT
fnp-2955	89	63	(	(	PUNCT
fnp-2955	89	64	25	25	NUM
fnp-2955	89	65	)	)	PUNCT
fnp-2955	89	66	.	.	PUNCT
fnp-2955	90	1	a	a	DET
fnp-2955	90	2	common	common	ADJ
fnp-2955	90	3	variation	variation	NOUN
fnp-2955	90	4	in	in	ADP
fnp-2955	90	5	the	the	DET
fnp-2955	90	6	col4a2	col4a2	NOUN
fnp-2955	90	7	gene	gene	NOUN
fnp-2955	90	8	is	be	AUX
fnp-2955	90	9	associated	associate	VERB
fnp-2955	90	10	with	with	ADP
fnp-2955	90	11	patients	patient	NOUN
fnp-2955	90	12	with	with	ADP
fnp-2955	90	13	intracerebral	intracerebral	ADJ
fnp-2955	90	14	haemorrhage	haemorrhage	NOUN
fnp-2955	90	15	(	(	PUNCT
fnp-2955	90	16	26	26	NUM
fnp-2955	90	17	)	)	PUNCT
fnp-2955	90	18	,	,	PUNCT
fnp-2955	90	19	which	which	PRON
fnp-2955	90	20	is	be	AUX
fnp-2955	90	21	one	one	NUM
fnp-2955	90	22	of	of	ADP
fnp-2955	90	23	the	the	DET
fnp-2955	90	24	most	most	ADV
fnp-2955	90	25	frequent	frequent	ADJ
fnp-2955	90	26	caa	caa	NOUN
fnp-2955	90	27	-	-	PUNCT
fnp-2955	90	28	related	relate	VERB
fnp-2955	90	29	cerebrovascular	cerebrovascular	ADJ
fnp-2955	90	30	complications	complication	NOUN
fnp-2955	90	31	.	.	PUNCT
fnp-2955	91	1	consistent	consistent	ADJ
fnp-2955	91	2	with	with	ADP
fnp-2955	91	3	the	the	DET
fnp-2955	91	4	current	current	ADJ
fnp-2955	91	5	proteomic	proteomic	ADJ
fnp-2955	91	6	results	result	NOUN
fnp-2955	91	7	,	,	PUNCT
fnp-2955	91	8	previous	previous	ADJ
fnp-2955	91	9	studies	study	NOUN
fnp-2955	91	10	have	have	AUX
fnp-2955	91	11	reported	report	VERB
fnp-2955	91	12	increased	increase	VERB
fnp-2955	91	13	collagen	collagen	NOUN
fnp-2955	91	14	iv	iv	NOUN
fnp-2955	91	15	expression	expression	NOUN
fnp-2955	91	16	in	in	ADP
fnp-2955	91	17	cerebral	cerebral	ADJ
fnp-2955	91	18	microvessels	microvessel	NOUN
fnp-2955	91	19	in	in	ADP
fnp-2955	91	20	patients	patient	NOUN
fnp-2955	91	21	with	with	ADP
fnp-2955	91	22	alzheimer	alzheimer	PROPN
fnp-2955	91	23	’s	’s	PART
fnp-2955	91	24	disease	disease	NOUN
fnp-2955	91	25	(	(	PUNCT
fnp-2955	91	26	27	27	NUM
fnp-2955	91	27	)	)	PUNCT
fnp-2955	91	28	and	and	CCONJ
fnp-2955	91	29	increased	increase	VERB
fnp-2955	91	30	collagen	collagen	NOUN
fnp-2955	91	31	iv	iv	ADP
fnp-2955	91	32	immunostaining	immunostaine	VERB
fnp-2955	91	33	in	in	ADP
fnp-2955	91	34	the	the	DET
fnp-2955	91	35	leptomeningeal	leptomeningeal	NOUN
fnp-2955	91	36	arteries	artery	NOUN
fnp-2955	91	37	in	in	ADP
fnp-2955	91	38	hereditary	hereditary	ADJ
fnp-2955	91	39	cystatin	cystatin	NOUN
fnp-2955	91	40	c	c	PROPN
fnp-2955	91	41	amyloid	amyloid	NOUN
fnp-2955	91	42	angiopathy	angiopathy	ADJ
fnp-2955	91	43	(	(	PUNCT
fnp-2955	91	44	28	28	NUM
fnp-2955	91	45	)	)	PUNCT
fnp-2955	91	46	.	.	PUNCT
fnp-2955	92	1	a	a	DET
fnp-2955	92	2	recent	recent	ADJ
fnp-2955	92	3	proteomic	proteomic	ADJ
fnp-2955	92	4	study	study	NOUN
fnp-2955	92	5	of	of	ADP
fnp-2955	92	6	the	the	DET
fnp-2955	92	7	grey	grey	ADJ
fnp-2955	92	8	matter	matter	NOUN
fnp-2955	92	9	in	in	ADP
fnp-2955	92	10	ad	ad	NOUN
fnp-2955	92	11	with	with	ADP
fnp-2955	92	12	caa	caa	NOUN
fnp-2955	92	13	type	type	NOUN
fnp-2955	92	14	1	1	NUM
fnp-2955	92	15	(	(	PUNCT
fnp-2955	92	16	predominantly	predominantly	ADV
fnp-2955	92	17	capillary	capillary	ADJ
fnp-2955	92	18	caa	caa	NOUN
fnp-2955	92	19	)	)	PUNCT
fnp-2955	92	20	has	have	AUX
fnp-2955	92	21	identified	identify	VERB
fnp-2955	92	22	collagen	collagen	NOUN
fnp-2955	92	23	alpha-2(vi	alpha-2(vi	PROPN
fnp-2955	92	24	)	)	PUNCT
fnp-2955	92	25	(	(	PUNCT
fnp-2955	92	26	col6a2	col6a2	NOUN
fnp-2955	92	27	)	)	PUNCT
fnp-2955	92	28	as	as	SCONJ
fnp-2955	92	29	increased	increase	VERB
fnp-2955	92	30	in	in	ADP
fnp-2955	92	31	the	the	DET
fnp-2955	92	32	grey	grey	ADJ
fnp-2955	92	33	matter	matter	NOUN
fnp-2955	92	34	of	of	ADP
fnp-2955	92	35	caa	caa	NOUN
fnp-2955	92	36	type	type	NOUN
fnp-2955	92	37	1(29	1(29	NUM
fnp-2955	92	38	)	)	PUNCT
fnp-2955	92	39	.	.	PUNCT
fnp-2955	93	1	perlecan	perlecan	PROPN
fnp-2955	93	2	is	be	AUX
fnp-2955	93	3	a	a	DET
fnp-2955	93	4	heparan	heparan	ADJ
fnp-2955	93	5	sulfate	sulfate	NOUN
fnp-2955	93	6	proteoglycan	proteoglycan	NOUN
fnp-2955	93	7	2	2	NUM
fnp-2955	93	8	(	(	PUNCT
fnp-2955	93	9	hspg2	hspg2	NOUN
fnp-2955	93	10	)	)	PUNCT
fnp-2955	93	11	,	,	PUNCT
fnp-2955	93	12	also	also	ADV
fnp-2955	93	13	a	a	DET
fnp-2955	93	14	component	component	NOUN
fnp-2955	93	15	of	of	ADP
fnp-2955	93	16	bm	bm	PROPN
fnp-2955	93	17	and	and	CCONJ
fnp-2955	93	18	provides	provide	VERB
fnp-2955	93	19	dynamic	dynamic	ADJ
fnp-2955	93	20	flexibility	flexibility	NOUN
fnp-2955	93	21	to	to	ADP
fnp-2955	93	22	the	the	DET
fnp-2955	93	23	bm	bm	PROPN
fnp-2955	93	24	,	,	PUNCT
fnp-2955	93	25	while	while	SCONJ
fnp-2955	93	26	promoting	promote	VERB
fnp-2955	93	27	the	the	DET
fnp-2955	93	28	aggregation	aggregation	NOUN
fnp-2955	93	29	of	of	ADP
fnp-2955	93	30	aβ	aβ	PROPN
fnp-2955	93	31	(	(	PUNCT
fnp-2955	93	32	30	30	NUM
fnp-2955	93	33	,	,	PUNCT
fnp-2955	93	34	31	31	NUM
fnp-2955	93	35	)	)	PUNCT
fnp-2955	93	36	.	.	PUNCT
fnp-2955	94	1	pathological	pathological	ADJ
fnp-2955	94	2	studies	study	NOUN
fnp-2955	94	3	have	have	AUX
fnp-2955	94	4	reported	report	VERB
fnp-2955	94	5	increased	increase	VERB
fnp-2955	94	6	expression	expression	NOUN
fnp-2955	94	7	of	of	ADP
fnp-2955	94	8	hspg2	hspg2	PROPN
fnp-2955	94	9	in	in	ADP
fnp-2955	94	10	alzheimer	alzheimer	PROPN
fnp-2955	94	11	’s	’s	PART
fnp-2955	94	12	disease	disease	NOUN
fnp-2955	94	13	(	(	PUNCT
fnp-2955	94	14	32	32	NUM
fnp-2955	94	15	)	)	PUNCT
fnp-2955	94	16	with	with	ADP
fnp-2955	94	17	a	a	DET
fnp-2955	94	18	significant	significant	ADJ
fnp-2955	94	19	association	association	NOUN
fnp-2955	94	20	of	of	ADP
fnp-2955	94	21	hspg2	hspg2	PROPN
fnp-2955	94	22	polymorphism	polymorphism	NOUN
fnp-2955	94	23	in	in	ADP
fnp-2955	94	24	apolipoprotein	apolipoprotein	ADJ
fnp-2955	94	25	ε4	ε4	NOUN
fnp-2955	94	26	allele	allele	NOUN
fnp-2955	94	27	carriers	carrier	NOUN
fnp-2955	94	28	(	(	PUNCT
fnp-2955	94	29	33	33	NUM
fnp-2955	94	30	)	)	PUNCT
fnp-2955	94	31	.	.	PUNCT
fnp-2955	95	1	the	the	DET
fnp-2955	95	2	upregulation	upregulation	NOUN
fnp-2955	95	3	of	of	ADP
fnp-2955	95	4	col4a2	col4a2	NOUN
fnp-2955	95	5	and	and	CCONJ
fnp-2955	95	6	hspg2	hspg2	PROPN
fnp-2955	95	7	have	have	AUX
fnp-2955	95	8	been	be	AUX
fnp-2955	95	9	observed	observe	VERB
fnp-2955	95	10	in	in	ADP
fnp-2955	95	11	other	other	ADJ
fnp-2955	95	12	studies	study	NOUN
fnp-2955	95	13	in	in	ADP
fnp-2955	95	14	the	the	DET
fnp-2955	95	15	grey	grey	ADJ
fnp-2955	95	16	matter	matter	NOUN
fnp-2955	95	17	,	,	PUNCT
fnp-2955	95	18	but	but	CCONJ
fnp-2955	95	19	their	their	PRON
fnp-2955	95	20	increase	increase	NOUN
fnp-2955	95	21	in	in	ADP
fnp-2955	95	22	the	the	DET
fnp-2955	95	23	white	white	ADJ
fnp-2955	95	24	matter	matter	NOUN
fnp-2955	95	25	of	of	ADP
fnp-2955	95	26	caa	caa	NOUN
fnp-2955	95	27	cases	case	NOUN
fnp-2955	95	28	in	in	ADP
fnp-2955	95	29	the	the	DET
fnp-2955	95	30	present	present	ADJ
fnp-2955	95	31	study	study	NOUN
fnp-2955	95	32	demonstrate	demonstrate	VERB
fnp-2955	95	33	the	the	DET
fnp-2955	95	34	widespread	widespread	ADJ
fnp-2955	95	35	changes	change	NOUN
fnp-2955	95	36	in	in	ADP
fnp-2955	95	37	the	the	DET
fnp-2955	95	38	extracellular	extracellular	ADJ
fnp-2955	95	39	matrix	matrix	NOUN
fnp-2955	95	40	in	in	ADP
fnp-2955	95	41	the	the	DET
fnp-2955	95	42	brain	brain	NOUN
fnp-2955	95	43	,	,	PUNCT
fnp-2955	95	44	reflected	reflect	VERB
fnp-2955	95	45	in	in	ADP
fnp-2955	95	46	a	a	DET
fnp-2955	95	47	failure	failure	NOUN
fnp-2955	95	48	of	of	ADP
fnp-2955	95	49	intramural	intramural	ADJ
fnp-2955	95	50	periarterial	periarterial	ADJ
fnp-2955	95	51	drainage	drainage	NOUN
fnp-2955	95	52	(	(	PUNCT
fnp-2955	95	53	ipad	ipad	NOUN
fnp-2955	95	54	)	)	PUNCT
fnp-2955	95	55	.	.	PUNCT
fnp-2955	96	1	emilin-2	emilin-2	PROPN
fnp-2955	96	2	was	be	AUX
fnp-2955	96	3	expressed	express	VERB
fnp-2955	96	4	at	at	ADP
fnp-2955	96	5	higher	high	ADJ
fnp-2955	96	6	levels	level	NOUN
fnp-2955	96	7	in	in	ADP
fnp-2955	96	8	the	the	DET
fnp-2955	96	9	white	white	ADJ
fnp-2955	96	10	matter	matter	NOUN
fnp-2955	96	11	from	from	ADP
fnp-2955	96	12	brains	brain	NOUN
fnp-2955	96	13	with	with	ADP
fnp-2955	96	14	caa	caa	NOUN
fnp-2955	96	15	vs.	vs.	ADP
fnp-2955	96	16	controls	control	NOUN
fnp-2955	96	17	.	.	PUNCT
fnp-2955	97	1	emilin-2	emilin-2	PROPN
fnp-2955	97	2	is	be	AUX
fnp-2955	97	3	part	part	NOUN
fnp-2955	97	4	of	of	ADP
fnp-2955	97	5	the	the	DET
fnp-2955	97	6	eden	eden	PROPN
fnp-2955	97	7	(	(	PUNCT
fnp-2955	97	8	emi	emi	NOUN
fnp-2955	97	9	domain	domain	NOUN
fnp-2955	97	10	endowed	endow	VERB
fnp-2955	97	11	)	)	PUNCT
fnp-2955	97	12	spectrum	spectrum	NOUN
fnp-2955	97	13	of	of	ADP
fnp-2955	97	14	proteins	protein	NOUN
fnp-2955	97	15	(	(	PUNCT
fnp-2955	97	16	34	34	NUM
fnp-2955	97	17	)	)	PUNCT
fnp-2955	97	18	,	,	PUNCT
fnp-2955	97	19	with	with	ADP
fnp-2955	97	20	roles	role	NOUN
fnp-2955	97	21	in	in	ADP
fnp-2955	97	22	angiogenesis	angiogenesis	NOUN
fnp-2955	97	23	,	,	PUNCT
fnp-2955	97	24	as	as	ADV
fnp-2955	97	25	well	well	ADV
fnp-2955	97	26	as	as	ADP
fnp-2955	97	27	cell	cell	NOUN
fnp-2955	97	28	adhesion	adhesion	NOUN
fnp-2955	97	29	/	/	SYM
fnp-2955	97	30	migration	migration	NOUN
fnp-2955	97	31	(	(	PUNCT
fnp-2955	97	32	34	34	NUM
fnp-2955	97	33	,	,	PUNCT
fnp-2955	97	34	35	35	NUM
fnp-2955	97	35	)	)	PUNCT
fnp-2955	97	36	.	.	PUNCT
fnp-2955	98	1	emilin-2	emilin-2	PROPN
fnp-2955	98	2	possesses	possess	VERB
fnp-2955	98	3	the	the	DET
fnp-2955	98	4	gc1q	gc1q	NOUN
fnp-2955	98	5	domain	domain	NOUN
fnp-2955	98	6	,	,	PUNCT
fnp-2955	98	7	which	which	PRON
fnp-2955	98	8	interacts	interact	VERB
fnp-2955	98	9	with	with	ADP
fnp-2955	98	10	α4β1	α4β1	ADV
fnp-2955	98	11	integrin	integrin	NOUN
fnp-2955	98	12	,	,	PUNCT
fnp-2955	98	13	which	which	PRON
fnp-2955	98	14	in	in	ADP
fnp-2955	98	15	turn	turn	NOUN
fnp-2955	98	16	binds	bind	VERB
fnp-2955	98	17	to	to	ADP
fnp-2955	98	18	fibronectin	fibronectin	NOUN
fnp-2955	98	19	,	,	PUNCT
fnp-2955	98	20	a	a	DET
fnp-2955	98	21	major	major	ADJ
fnp-2955	98	22	component	component	NOUN
fnp-2955	98	23	of	of	ADP
fnp-2955	98	24	bm	bm	PROPN
fnp-2955	98	25	(	(	PUNCT
fnp-2955	98	26	36	36	NUM
fnp-2955	98	27	)	)	PUNCT
fnp-2955	98	28	.	.	PUNCT
fnp-2955	99	1	recent	recent	ADJ
fnp-2955	99	2	studies	study	NOUN
fnp-2955	99	3	demonstrated	demonstrate	VERB
fnp-2955	99	4	a	a	DET
fnp-2955	99	5	reduction	reduction	NOUN
fnp-2955	99	6	in	in	ADP
fnp-2955	99	7	fibronectin	fibronectin	NOUN
fnp-2955	99	8	in	in	ADP
fnp-2955	99	9	post	post	ADJ
fnp-2955	99	10	-	-	ADJ
fnp-2955	99	11	mortem	mortem	ADJ
fnp-2955	99	12	brains	brain	NOUN
fnp-2955	99	13	with	with	ADP
fnp-2955	99	14	white	white	ADJ
fnp-2955	99	15	matter	matter	NOUN
fnp-2955	99	16	hyperintensities	hyperintensitie	NOUN
fnp-2955	99	17	as	as	ADV
fnp-2955	99	18	well	well	ADV
fnp-2955	99	19	as	as	ADP
fnp-2955	99	20	on	on	ADP
fnp-2955	99	21	cerebrovascular	cerebrovascular	ADJ
fnp-2955	99	22	smooth	smooth	ADJ
fnp-2955	99	23	muscle	muscle	NOUN
fnp-2955	99	24	cell	cell	NOUN
fnp-2955	99	25	cultures	culture	NOUN
fnp-2955	99	26	exposed	expose	VERB
fnp-2955	99	27	to	to	ADP
fnp-2955	99	28	hypercapnia	hypercapnia	PROPN
fnp-2955	99	29	as	as	ADP
fnp-2955	99	30	a	a	DET
fnp-2955	99	31	model	model	NOUN
fnp-2955	99	32	of	of	ADP
fnp-2955	99	33	hypoperfusion	hypoperfusion	NOUN
fnp-2955	99	34	(	(	PUNCT
fnp-2955	99	35	37	37	NUM
fnp-2955	99	36	)	)	PUNCT
fnp-2955	99	37	.	.	PUNCT
fnp-2955	100	1	although	although	SCONJ
fnp-2955	100	2	the	the	DET
fnp-2955	100	3	expression	expression	NOUN
fnp-2955	100	4	of	of	ADP
fnp-2955	100	5	emilin-2	emilin-2	NUM
fnp-2955	100	6	in	in	ADP
fnp-2955	100	7	brain	brain	NOUN
fnp-2955	100	8	is	be	AUX
fnp-2955	100	9	relatively	relatively	ADV
fnp-2955	100	10	small	small	ADJ
fnp-2955	100	11	compared	compare	VERB
fnp-2955	100	12	to	to	ADP
fnp-2955	100	13	other	other	ADJ
fnp-2955	100	14	organs	organ	NOUN
fnp-2955	100	15	and	and	CCONJ
fnp-2955	100	16	the	the	DET
fnp-2955	100	17	physiological	physiological	ADJ
fnp-2955	100	18	role	role	NOUN
fnp-2955	100	19	of	of	ADP
fnp-2955	100	20	emilin-2	emilin-2	NUM
fnp-2955	100	21	is	be	AUX
fnp-2955	100	22	unclear	unclear	ADJ
fnp-2955	100	23	(	(	PUNCT
fnp-2955	100	24	38	38	NUM
fnp-2955	100	25	)	)	PUNCT
fnp-2955	100	26	,	,	PUNCT
fnp-2955	100	27	its	its	PRON
fnp-2955	100	28	association	association	NOUN
fnp-2955	100	29	with	with	ADP
fnp-2955	100	30	bm	bm	PROPN
fnp-2955	100	31	(	(	PUNCT
fnp-2955	100	32	39	39	NUM
fnp-2955	100	33	)	)	PUNCT
fnp-2955	100	34	suggests	suggest	VERB
fnp-2955	100	35	that	that	SCONJ
fnp-2955	100	36	the	the	DET
fnp-2955	100	37	upregulation	upregulation	NOUN
fnp-2955	100	38	of	of	ADP
fnp-2955	100	39	emilin-2	emilin-2	NUM
fnp-2955	100	40	reflects	reflect	VERB
fnp-2955	100	41	a	a	DET
fnp-2955	100	42	compensatory	compensatory	ADJ
fnp-2955	100	43	upregulation	upregulation	NOUN
fnp-2955	100	44	of	of	ADP
fnp-2955	100	45	angiogenesis	angiogenesis	NOUN
fnp-2955	100	46	and	and	CCONJ
fnp-2955	100	47	ipad	ipad	NOUN
fnp-2955	100	48	in	in	ADP
fnp-2955	100	49	the	the	DET
fnp-2955	100	50	face	face	NOUN
fnp-2955	100	51	of	of	ADP
fnp-2955	100	52	the	the	DET
fnp-2955	100	53	hypoperfusion	hypoperfusion	NOUN
fnp-2955	100	54	and	and	CCONJ
fnp-2955	100	55	altered	alter	VERB
fnp-2955	100	56	extracellular	extracellular	ADJ
fnp-2955	100	57	matrix	matrix	NOUN
fnp-2955	100	58	characteristics	characteristic	NOUN
fnp-2955	100	59	of	of	ADP
fnp-2955	100	60	the	the	DET
fnp-2955	100	61	white	white	ADJ
fnp-2955	100	62	matter	matter	NOUN
fnp-2955	100	63	in	in	ADP
fnp-2955	100	64	caa	caa	PROPN
fnp-2955	100	65	(	(	PUNCT
fnp-2955	100	66	15	15	NUM
fnp-2955	100	67	,	,	PUNCT
fnp-2955	100	68	40	40	NUM
fnp-2955	100	69	)	)	PUNCT
fnp-2955	100	70	.	.	PUNCT
fnp-2955	101	1	talin-1	talin-1	PROPN
fnp-2955	101	2	(	(	PUNCT
fnp-2955	101	3	tln1	tln1	PROPN
fnp-2955	101	4	)	)	PUNCT
fnp-2955	101	5	is	be	AUX
fnp-2955	101	6	a	a	DET
fnp-2955	101	7	heavy	heavy	ADJ
fnp-2955	101	8	protein	protein	NOUN
fnp-2955	101	9	that	that	PRON
fnp-2955	101	10	contains	contain	VERB
fnp-2955	101	11	a	a	DET
fnp-2955	101	12	c	c	NOUN
fnp-2955	101	13	-	-	PUNCT
fnp-2955	101	14	terminal	terminal	ADJ
fnp-2955	101	15	flexible	flexible	ADJ
fnp-2955	101	16	rod	rod	NOUN
fnp-2955	101	17	domain	domain	NOUN
fnp-2955	101	18	which	which	PRON
fnp-2955	101	19	binds	bind	VERB
fnp-2955	101	20	to	to	ADP
fnp-2955	101	21	vinculin	vinculin	NOUN
fnp-2955	101	22	and	and	CCONJ
fnp-2955	101	23	actin	actin	NOUN
fnp-2955	101	24	while	while	SCONJ
fnp-2955	101	25	the	the	DET
fnp-2955	101	26	n	n	CCONJ
fnp-2955	101	27	-	-	PUNCT
fnp-2955	101	28	terminal	terminal	ADJ
fnp-2955	101	29	head	head	NOUN
fnp-2955	101	30	binds	bind	VERB
fnp-2955	101	31	to	to	PART
fnp-2955	101	32	integrin	integrin	VERB
fnp-2955	101	33	cytoplasmic	cytoplasmic	ADJ
fnp-2955	101	34	tails	tail	NOUN
fnp-2955	101	35	(	(	PUNCT
fnp-2955	101	36	41	41	NUM
fnp-2955	101	37	-	-	SYM
fnp-2955	101	38	43	43	NUM
fnp-2955	101	39	)	)	PUNCT
fnp-2955	101	40	.	.	PUNCT
fnp-2955	102	1	binding	bind	VERB
fnp-2955	102	2	of	of	ADP
fnp-2955	102	3	the	the	DET
fnp-2955	102	4	talin	talin	NOUN
fnp-2955	102	5	head	head	NOUN
fnp-2955	102	6	to	to	ADP
fnp-2955	102	7	integrin	integrin	PROPN
fnp-2955	102	8	is	be	AUX
fnp-2955	102	9	a	a	DET
fnp-2955	102	10	key	key	ADJ
fnp-2955	102	11	step	step	NOUN
fnp-2955	102	12	required	require	VERB
fnp-2955	102	13	for	for	ADP
fnp-2955	102	14	integrin	integrin	NOUN
fnp-2955	102	15	activation	activation	NOUN
fnp-2955	102	16	(	(	PUNCT
fnp-2955	102	17	44	44	NUM
fnp-2955	102	18	,	,	PUNCT
fnp-2955	102	19	45	45	NUM
fnp-2955	102	20	)	)	PUNCT
fnp-2955	102	21	.	.	PUNCT
fnp-2955	103	1	integrins	integrin	NOUN
fnp-2955	103	2	are	be	AUX
fnp-2955	103	3	essential	essential	ADJ
fnp-2955	103	4	for	for	ADP
fnp-2955	103	5	cell	cell	NOUN
fnp-2955	103	6	adhesion	adhesion	NOUN
fnp-2955	103	7	and	and	CCONJ
fnp-2955	103	8	α5β1	α5β1	NUM
fnp-2955	103	9	is	be	AUX
fnp-2955	103	10	anti	anti	ADJ
fnp-2955	103	11	-	-	ADJ
fnp-2955	103	12	apoptotic	apoptotic	ADJ
fnp-2955	103	13	and	and	CCONJ
fnp-2955	103	14	a	a	DET
fnp-2955	103	15	receptor	receptor	NOUN
fnp-2955	103	16	for	for	ADP
fnp-2955	103	17	aβ	aβ	PROPN
fnp-2955	103	18	(	(	PUNCT
fnp-2955	103	19	46	46	NUM
fnp-2955	103	20	)	)	PUNCT
fnp-2955	103	21	.	.	PUNCT
fnp-2955	104	1	as	as	SCONJ
fnp-2955	104	2	talin	talin	NOUN
fnp-2955	104	3	also	also	ADV
fnp-2955	104	4	promotes	promote	VERB
fnp-2955	104	5	axon	axon	ADJ
fnp-2955	104	6	growth	growth	NOUN
fnp-2955	104	7	(	(	PUNCT
fnp-2955	104	8	47	47	NUM
fnp-2955	104	9	)	)	PUNCT
fnp-2955	104	10	,	,	PUNCT
fnp-2955	104	11	it	it	PRON
fnp-2955	104	12	is	be	AUX
fnp-2955	104	13	possible	possible	ADJ
fnp-2955	104	14	that	that	SCONJ
fnp-2955	104	15	it	it	PRON
fnp-2955	104	16	is	be	AUX
fnp-2955	104	17	upregulated	upregulate	VERB
fnp-2955	104	18	as	as	ADP
fnp-2955	104	19	a	a	DET
fnp-2955	104	20	compensatory	compensatory	ADJ
fnp-2955	104	21	effect	effect	NOUN
fnp-2955	104	22	of	of	ADP
fnp-2955	104	23	axonal	axonal	ADJ
fnp-2955	104	24	and	and	CCONJ
fnp-2955	104	25	synapse	synapse	ADJ
fnp-2955	104	26	destruction	destruction	NOUN
fnp-2955	104	27	in	in	ADP
fnp-2955	104	28	white	white	ADJ
fnp-2955	104	29	matter	matter	NOUN
fnp-2955	104	30	lesions	lesion	NOUN
fnp-2955	104	31	(	(	PUNCT
fnp-2955	104	32	22	22	NUM
fnp-2955	104	33	)	)	PUNCT
fnp-2955	104	34	.	.	PUNCT
fnp-2955	105	1	in	in	ADP
fnp-2955	105	2	the	the	DET
fnp-2955	105	3	present	present	ADJ
fnp-2955	105	4	study	study	NOUN
fnp-2955	105	5	,	,	PUNCT
fnp-2955	105	6	the	the	DET
fnp-2955	105	7	expression	expression	NOUN
fnp-2955	105	8	of	of	ADP
fnp-2955	105	9	clu	clu	PROPN
fnp-2955	105	10	(	(	PUNCT
fnp-2955	105	11	clusterin	clusterin	NOUN
fnp-2955	105	12	)	)	PUNCT
fnp-2955	105	13	was	be	AUX
fnp-2955	105	14	higher	high	ADJ
fnp-2955	105	15	in	in	ADP
fnp-2955	105	16	the	the	DET
fnp-2955	105	17	white	white	ADJ
fnp-2955	105	18	matter	matter	NOUN
fnp-2955	105	19	of	of	ADP
fnp-2955	105	20	caa	caa	NOUN
fnp-2955	105	21	cases	case	NOUN
fnp-2955	105	22	compared	compare	VERB
fnp-2955	105	23	to	to	ADP
fnp-2955	105	24	controls	control	NOUN
fnp-2955	105	25	.	.	PUNCT
fnp-2955	106	1	our	our	PRON
fnp-2955	106	2	own	own	ADJ
fnp-2955	106	3	prior	prior	ADJ
fnp-2955	106	4	proteomic	proteomic	ADJ
fnp-2955	106	5	study	study	NOUN
fnp-2955	106	6	of	of	ADP
fnp-2955	106	7	leptomeningeal	leptomeningeal	ADJ
fnp-2955	106	8	arteries	artery	NOUN
fnp-2955	106	9	in	in	ADP
fnp-2955	106	10	caa	caa	NOUN
fnp-2955	106	11	revealed	reveal	VERB
fnp-2955	106	12	a	a	DET
fnp-2955	106	13	high	high	ADJ
fnp-2955	106	14	expression	expression	NOUN
fnp-2955	106	15	of	of	ADP
fnp-2955	106	16	clu	clu	PROPN
fnp-2955	106	17	,	,	PUNCT
fnp-2955	106	18	and	and	CCONJ
fnp-2955	106	19	a	a	DET
fnp-2955	106	20	recent	recent	ADJ
fnp-2955	106	21	study	study	NOUN
fnp-2955	106	22	on	on	ADP
fnp-2955	106	23	the	the	DET
fnp-2955	106	24	proteomic	proteomic	ADJ
fnp-2955	106	25	expression	expression	NOUN
fnp-2955	106	26	of	of	ADP
fnp-2955	106	27	grey	grey	PROPN
fnp-2955	106	28	matter	matter	NOUN
fnp-2955	106	29	in	in	ADP
fnp-2955	106	30	caa	caa	NOUN
fnp-2955	106	31	also	also	ADV
fnp-2955	106	32	revealed	reveal	VERB
fnp-2955	106	33	an	an	DET
fnp-2955	106	34	increased	increase	VERB
fnp-2955	106	35	expression	expression	NOUN
fnp-2955	106	36	of	of	ADP
fnp-2955	106	37	clu	clu	PROPN
fnp-2955	106	38	(	(	PUNCT
fnp-2955	106	39	17	17	NUM
fnp-2955	106	40	)	)	PUNCT
fnp-2955	106	41	.	.	PUNCT
fnp-2955	107	1	genome	genome	NOUN
fnp-2955	107	2	-	-	PUNCT
fnp-2955	107	3	wide	wide	ADJ
fnp-2955	107	4	association	association	NOUN
fnp-2955	107	5	studies	study	NOUN
fnp-2955	107	6	identified	identify	VERB
fnp-2955	107	7	variations	variation	NOUN
fnp-2955	107	8	in	in	ADP
fnp-2955	107	9	clu	clu	NOUN
fnp-2955	107	10	expression	expression	NOUN
fnp-2955	107	11	associated	associate	VERB
fnp-2955	107	12	with	with	ADP
fnp-2955	107	13	alzheimer	alzheimer	PROPN
fnp-2955	107	14	’s	’s	PART
fnp-2955	107	15	disease	disease	NOUN
fnp-2955	107	16	(	(	PUNCT
fnp-2955	107	17	48	48	NUM
fnp-2955	107	18	,	,	PUNCT
fnp-2955	107	19	49	49	NUM
fnp-2955	107	20	)	)	PUNCT
fnp-2955	107	21	.	.	PUNCT
fnp-2955	108	1	clusterin	clusterin	PROPN
fnp-2955	108	2	may	may	AUX
fnp-2955	108	3	act	act	VERB
fnp-2955	108	4	as	as	ADP
fnp-2955	108	5	a	a	DET
fnp-2955	108	6	chaperone	chaperone	NOUN
fnp-2955	108	7	molecule	molecule	NOUN
fnp-2955	108	8	that	that	PRON
fnp-2955	108	9	facilitates	facilitate	VERB
fnp-2955	108	10	intramural	intramural	ADJ
fnp-2955	108	11	periarterial	periarterial	ADJ
fnp-2955	108	12	drainage	drainage	NOUN
fnp-2955	108	13	of	of	ADP
fnp-2955	108	14	soluble	soluble	ADJ
fnp-2955	108	15	aβ	aβ	NOUN
fnp-2955	108	16	(	(	PUNCT
fnp-2955	108	17	50	50	NUM
fnp-2955	108	18	)	)	PUNCT
fnp-2955	108	19	.	.	PUNCT
fnp-2955	109	1	increased	increase	VERB
fnp-2955	109	2	expression	expression	NOUN
fnp-2955	109	3	of	of	ADP
fnp-2955	109	4	clu	clu	PROPN
fnp-2955	109	5	may	may	AUX
fnp-2955	109	6	be	be	AUX
fnp-2955	109	7	a	a	DET
fnp-2955	109	8	compensatory	compensatory	ADJ
fnp-2955	109	9	mechanism	mechanism	NOUN
fnp-2955	109	10	to	to	ADP
fnp-2955	109	11	the	the	DET
fnp-2955	109	12	cerebrovascular	cerebrovascular	ADJ
fnp-2955	109	13	accumulation	accumulation	NOUN
fnp-2955	109	14	of	of	ADP
fnp-2955	109	15	aβ	aβ	PRON
fnp-2955	109	16	in	in	ADP
fnp-2955	109	17	these	these	DET
fnp-2955	109	18	cases	case	NOUN
fnp-2955	109	19	.	.	PUNCT
fnp-2955	110	1	proteins	protein	NOUN
fnp-2955	110	2	with	with	ADP
fnp-2955	110	3	decreased	decrease	VERB
fnp-2955	110	4	expression	expression	NOUN
fnp-2955	110	5	ide	ide	NOUN
fnp-2955	110	6	(	(	PUNCT
fnp-2955	110	7	insulin	insulin	NOUN
fnp-2955	110	8	-	-	PUNCT
fnp-2955	110	9	degrading	degrade	VERB
fnp-2955	110	10	enzyme	enzyme	NOUN
fnp-2955	110	11	)	)	PUNCT
fnp-2955	110	12	was	be	AUX
fnp-2955	110	13	significantly	significantly	ADV
fnp-2955	110	14	decreased	decrease	VERB
fnp-2955	110	15	in	in	ADP
fnp-2955	110	16	our	our	PRON
fnp-2955	110	17	study	study	NOUN
fnp-2955	110	18	.	.	PUNCT
fnp-2955	111	1	ide	ide	NOUN
fnp-2955	111	2	is	be	AUX
fnp-2955	111	3	a	a	DET
fnp-2955	111	4	key	key	ADJ
fnp-2955	111	5	enzyme	enzyme	NOUN
fnp-2955	111	6	that	that	PRON
fnp-2955	111	7	degrades	degrade	VERB
fnp-2955	111	8	aβ	aβ	PRON
fnp-2955	111	9	in	in	ADP
fnp-2955	111	10	the	the	DET
fnp-2955	111	11	extracellular	extracellular	ADJ
fnp-2955	111	12	spaces	space	NOUN
fnp-2955	111	13	(	(	PUNCT
fnp-2955	111	14	51	51	NUM
fnp-2955	111	15	)	)	PUNCT
fnp-2955	111	16	.	.	PUNCT
fnp-2955	112	1	in	in	ADP
fnp-2955	112	2	diabetes	diabetes	NOUN
fnp-2955	112	3	mellitus	mellitus	NOUN
fnp-2955	112	4	there	there	PRON
fnp-2955	112	5	is	be	VERB
fnp-2955	112	6	inhibition	inhibition	NOUN
fnp-2955	112	7	of	of	ADP
fnp-2955	112	8	aβ	aβ	DET
fnp-2955	112	9	degradation	degradation	NOUN
fnp-2955	112	10	directly	directly	ADV
fnp-2955	112	11	associated	associate	VERB
fnp-2955	112	12	with	with	ADP
fnp-2955	112	13	a	a	DET
fnp-2955	112	14	reduced	reduce	VERB
fnp-2955	112	15	activity	activity	NOUN
fnp-2955	112	16	of	of	ADP
fnp-2955	112	17	ide	ide	NOUN
fnp-2955	112	18	(	(	PUNCT
fnp-2955	112	19	52	52	NUM
fnp-2955	112	20	-	-	SYM
fnp-2955	112	21	54	54	NUM
fnp-2955	112	22	)	)	PUNCT
fnp-2955	112	23	.	.	PUNCT
fnp-2955	113	1	overexpression	overexpression	NOUN
fnp-2955	113	2	of	of	ADP
fnp-2955	113	3	ide	ide	ADJ
fnp-2955	113	4	ameliorates	ameliorate	NOUN
fnp-2955	113	5	aβ	aβ	PRON
fnp-2955	113	6	pathology	pathology	NOUN
fnp-2955	113	7	(	(	PUNCT
fnp-2955	113	8	55	55	NUM
fnp-2955	113	9	)	)	PUNCT
fnp-2955	113	10	.	.	PUNCT
fnp-2955	114	1	ide	ide	NOUN
fnp-2955	114	2	is	be	AUX
fnp-2955	114	3	expressed	express	VERB
fnp-2955	114	4	within	within	ADP
fnp-2955	114	5	the	the	DET
fnp-2955	114	6	vessel	vessel	NOUN
fnp-2955	114	7	walls	wall	NOUN
fnp-2955	114	8	and	and	CCONJ
fnp-2955	114	9	its	its	PRON
fnp-2955	114	10	activity	activity	NOUN
fnp-2955	114	11	is	be	AUX
fnp-2955	114	12	decreased	decrease	VERB
fnp-2955	114	13	in	in	ADP
fnp-2955	114	14	caa	caa	NOUN
fnp-2955	114	15	(	(	PUNCT
fnp-2955	114	16	56	56	NUM
fnp-2955	114	17	)	)	PUNCT
fnp-2955	114	18	.	.	PUNCT
fnp-2955	115	1	the	the	DET
fnp-2955	115	2	decreased	decrease	VERB
fnp-2955	115	3	expression	expression	NOUN
fnp-2955	115	4	of	of	ADP
fnp-2955	115	5	ide	ide	NOUN
fnp-2955	115	6	may	may	AUX
fnp-2955	115	7	reflect	reflect	VERB
fnp-2955	115	8	a	a	DET
fnp-2955	115	9	failure	failure	NOUN
fnp-2955	115	10	of	of	ADP
fnp-2955	115	11	the	the	DET
fnp-2955	115	12	proteolysis	proteolysis	NOUN
fnp-2955	115	13	and	and	CCONJ
fnp-2955	115	14	consequent	consequent	ADJ
fnp-2955	115	15	increased	increase	VERB
fnp-2955	115	16	toxicity	toxicity	NOUN
fnp-2955	115	17	of	of	ADP
fnp-2955	115	18	aβ	aβ	NOUN
fnp-2955	115	19	.	.	PUNCT
fnp-2955	116	1	the	the	DET
fnp-2955	116	2	expression	expression	NOUN
fnp-2955	116	3	of	of	ADP
fnp-2955	116	4	hbg1	hbg1	PROPN
fnp-2955	116	5	,	,	PUNCT
fnp-2955	116	6	the	the	DET
fnp-2955	116	7	γ(a)-globin	γ(a)-globin	PROPN
fnp-2955	116	8	subunit	subunit	NOUN
fnp-2955	116	9	of	of	ADP
fnp-2955	116	10	fetal	fetal	ADJ
fnp-2955	116	11	haemoglobin	haemoglobin	NOUN
fnp-2955	116	12	,	,	PUNCT
fnp-2955	116	13	was	be	AUX
fnp-2955	116	14	also	also	ADV
fnp-2955	116	15	decreased	decrease	VERB
fnp-2955	116	16	in	in	ADP
fnp-2955	116	17	our	our	PRON
fnp-2955	116	18	study	study	NOUN
fnp-2955	116	19	.	.	PUNCT
fnp-2955	117	1	hbg1	hbg1	PROPN
fnp-2955	117	2	is	be	AUX
fnp-2955	117	3	capable	capable	ADJ
fnp-2955	117	4	of	of	ADP
fnp-2955	117	5	strongly	strongly	ADV
fnp-2955	117	6	binding	binding	ADJ
fnp-2955	117	7	to	to	ADP
fnp-2955	117	8	aβ	aβ	PROPN
fnp-2955	117	9	(	(	PUNCT
fnp-2955	117	10	57	57	NUM
fnp-2955	117	11	)	)	PUNCT
fnp-2955	117	12	.	.	PUNCT
fnp-2955	118	1	an	an	DET
fnp-2955	118	2	animal	animal	NOUN
fnp-2955	118	3	model	model	NOUN
fnp-2955	118	4	of	of	ADP
fnp-2955	118	5	caa	caa	PROPN
fnp-2955	118	6	exhibited	exhibit	VERB
fnp-2955	118	7	impaired	impaired	ADJ
fnp-2955	118	8	aβ	aβ	DET
fnp-2955	118	9	transcytosis	transcytosis	NOUN
fnp-2955	118	10	from	from	ADP
fnp-2955	118	11	brain	brain	NOUN
fnp-2955	118	12	to	to	ADP
fnp-2955	118	13	blood	blood	NOUN
fnp-2955	118	14	,	,	PUNCT
fnp-2955	118	15	resulting	result	VERB
fnp-2955	118	16	in	in	ADP
fnp-2955	118	17	decreased	decrease	VERB
fnp-2955	118	18	level	level	NOUN
fnp-2955	118	19	of	of	ADP
fnp-2955	118	20	aβ	aβ	PRON
fnp-2955	118	21	in	in	ADP
fnp-2955	118	22	the	the	DET
fnp-2955	118	23	blood	blood	NOUN
fnp-2955	118	24	(	(	PUNCT
fnp-2955	118	25	58	58	NUM
fnp-2955	118	26	)	)	PUNCT
fnp-2955	118	27	.	.	PUNCT
fnp-2955	119	1	decreased	decrease	VERB
fnp-2955	119	2	expression	expression	NOUN
fnp-2955	119	3	of	of	ADP
fnp-2955	119	4	hbg1	hbg1	PROPN
fnp-2955	119	5	may	may	AUX
fnp-2955	119	6	result	result	VERB
fnp-2955	119	7	from	from	ADP
fnp-2955	119	8	reduced	reduced	ADJ
fnp-2955	119	9	level	level	NOUN
fnp-2955	119	10	of	of	ADP
fnp-2955	119	11	the	the	DET
fnp-2955	119	12	aβ	aβ	NOUN
fnp-2955	119	13	and	and	CCONJ
fnp-2955	119	14	hbg1	hbg1	ADJ
fnp-2955	119	15	complex	complex	NOUN
fnp-2955	119	16	in	in	ADP
fnp-2955	119	17	the	the	DET
fnp-2955	119	18	blood	blood	NOUN
fnp-2955	119	19	in	in	ADP
fnp-2955	119	20	cases	case	NOUN
fnp-2955	119	21	of	of	ADP
fnp-2955	119	22	caa	caa	NOUN
fnp-2955	119	23	.	.	PUNCT
fnp-2955	120	1	desmoplakin	desmoplakin	NOUN
fnp-2955	120	2	(	(	PUNCT
fnp-2955	120	3	dsp	dsp	NOUN
fnp-2955	120	4	)	)	PUNCT
fnp-2955	120	5	is	be	AUX
fnp-2955	120	6	a	a	DET
fnp-2955	120	7	desmosome	desmosome	ADV
fnp-2955	120	8	-	-	PUNCT
fnp-2955	120	9	associated	associate	VERB
fnp-2955	120	10	transmembrane	transmembrane	NOUN
fnp-2955	120	11	glycoprotein	glycoprotein	NOUN
fnp-2955	120	12	and	and	CCONJ
fnp-2955	120	13	maintains	maintain	VERB
fnp-2955	120	14	the	the	DET
fnp-2955	120	15	integrity	integrity	NOUN
fnp-2955	120	16	of	of	ADP
fnp-2955	120	17	the	the	DET
fnp-2955	120	18	epidermis	epidermis	NOUN
fnp-2955	120	19	and	and	CCONJ
fnp-2955	120	20	myocardium	myocardium	ADJ
fnp-2955	120	21	(	(	PUNCT
fnp-2955	120	22	59	59	NUM
fnp-2955	120	23	)	)	PUNCT
fnp-2955	120	24	.	.	PUNCT
fnp-2955	121	1	the	the	DET
fnp-2955	121	2	physiological	physiological	ADJ
fnp-2955	121	3	role	role	NOUN
fnp-2955	121	4	of	of	ADP
fnp-2955	121	5	desmoplakin	desmoplakin	NOUN
fnp-2955	121	6	in	in	ADP
fnp-2955	121	7	the	the	DET
fnp-2955	121	8	brain	brain	NOUN
fnp-2955	121	9	remains	remain	VERB
fnp-2955	121	10	unknown	unknown	ADJ
fnp-2955	121	11	.	.	PUNCT
fnp-2955	122	1	interestingly	interestingly	ADV
fnp-2955	122	2	,	,	PUNCT
fnp-2955	122	3	it	it	PRON
fnp-2955	122	4	was	be	AUX
fnp-2955	122	5	reported	report	VERB
fnp-2955	122	6	that	that	SCONJ
fnp-2955	122	7	desmoplakin	desmoplakin	NOUN
fnp-2955	122	8	is	be	AUX
fnp-2955	122	9	a	a	DET
fnp-2955	122	10	specific	specific	ADJ
fnp-2955	122	11	marker	marker	NOUN
fnp-2955	122	12	of	of	ADP
fnp-2955	122	13	lymphatic	lymphatic	ADJ
fnp-2955	122	14	vessels	vessel	NOUN
fnp-2955	122	15	in	in	ADP
fnp-2955	122	16	human	human	ADJ
fnp-2955	122	17	tongue	tongue	NOUN
fnp-2955	122	18	(	(	PUNCT
fnp-2955	122	19	60	60	NUM
fnp-2955	122	20	)	)	PUNCT
fnp-2955	122	21	.	.	PUNCT
fnp-2955	123	1	since	since	SCONJ
fnp-2955	123	2	ipad	ipad	NOUN
fnp-2955	123	3	represents	represent	VERB
fnp-2955	123	4	the	the	DET
fnp-2955	123	5	lymphatic	lymphatic	ADJ
fnp-2955	123	6	drainage	drainage	NOUN
fnp-2955	123	7	pathways	pathway	NOUN
fnp-2955	123	8	of	of	ADP
fnp-2955	123	9	the	the	DET
fnp-2955	123	10	brain	brain	NOUN
fnp-2955	123	11	parenchyma	parenchyma	NOUN
fnp-2955	123	12	,	,	PUNCT
fnp-2955	123	13	(	(	PUNCT
fnp-2955	123	14	61	61	NUM
fnp-2955	123	15	)	)	PUNCT
fnp-2955	123	16	a	a	DET
fnp-2955	123	17	decreased	decrease	VERB
fnp-2955	123	18	level	level	NOUN
fnp-2955	123	19	of	of	ADP
fnp-2955	123	20	desmoplakin	desmoplakin	NOUN
fnp-2955	123	21	may	may	AUX
fnp-2955	123	22	simply	simply	ADV
fnp-2955	123	23	reflect	reflect	VERB
fnp-2955	123	24	impaired	impaired	ADJ
fnp-2955	123	25	ipad	ipad	NOUN
fnp-2955	123	26	.	.	PUNCT
fnp-2955	124	1	the	the	DET
fnp-2955	124	2	present	present	ADJ
fnp-2955	124	3	study	study	NOUN
fnp-2955	124	4	has	have	VERB
fnp-2955	124	5	some	some	DET
fnp-2955	124	6	limitations	limitation	NOUN
fnp-2955	124	7	:	:	PUNCT
fnp-2955	124	8	firstly	firstly	ADV
fnp-2955	124	9	,	,	PUNCT
fnp-2955	124	10	the	the	DET
fnp-2955	124	11	sample	sample	NOUN
fnp-2955	124	12	size	size	NOUN
fnp-2955	124	13	is	be	AUX
fnp-2955	124	14	low	low	ADJ
fnp-2955	124	15	due	due	ADP
fnp-2955	124	16	to	to	ADP
fnp-2955	124	17	the	the	DET
fnp-2955	124	18	difficulty	difficulty	NOUN
fnp-2955	124	19	in	in	ADP
fnp-2955	124	20	obtaining	obtain	VERB
fnp-2955	124	21	fresh	fresh	ADJ
fnp-2955	124	22	frozen	frozen	ADJ
fnp-2955	124	23	white	white	ADJ
fnp-2955	124	24	matter	matter	NOUN
fnp-2955	124	25	.	.	PUNCT
fnp-2955	125	1	this	this	PRON
fnp-2955	125	2	has	have	AUX
fnp-2955	125	3	also	also	ADV
fnp-2955	125	4	prevented	prevent	VERB
fnp-2955	125	5	us	we	PRON
fnp-2955	125	6	from	from	ADP
fnp-2955	125	7	performing	perform	VERB
fnp-2955	125	8	an	an	DET
fnp-2955	125	9	analysis	analysis	NOUN
fnp-2955	125	10	by	by	ADP
fnp-2955	125	11	sex	sex	NOUN
fnp-2955	125	12	or	or	CCONJ
fnp-2955	125	13	any	any	DET
fnp-2955	125	14	other	other	ADJ
fnp-2955	125	15	stratification	stratification	NOUN
fnp-2955	125	16	.	.	PUNCT
fnp-2955	126	1	secondly	secondly	ADV
fnp-2955	126	2	,	,	PUNCT
fnp-2955	126	3	it	it	PRON
fnp-2955	126	4	was	be	AUX
fnp-2955	126	5	not	not	PART
fnp-2955	126	6	possible	possible	ADJ
fnp-2955	126	7	to	to	PART
fnp-2955	126	8	specifically	specifically	ADV
fnp-2955	126	9	select	select	VERB
fnp-2955	126	10	areas	area	NOUN
fnp-2955	126	11	of	of	ADP
fnp-2955	126	12	wmh	wmh	NOUN
fnp-2955	126	13	from	from	ADP
fnp-2955	126	14	the	the	DET
fnp-2955	126	15	frozen	frozen	ADJ
fnp-2955	126	16	samples	sample	NOUN
fnp-2955	126	17	of	of	ADP
fnp-2955	126	18	brain	brain	NOUN
fnp-2955	126	19	and	and	CCONJ
fnp-2955	126	20	to	to	PART
fnp-2955	126	21	study	study	VERB
fnp-2955	126	22	them	they	PRON
fnp-2955	126	23	separately	separately	ADV
fnp-2955	126	24	.	.	PUNCT
fnp-2955	127	1	nevertheless	nevertheless	ADV
fnp-2955	127	2	,	,	PUNCT
fnp-2955	127	3	our	our	PRON
fnp-2955	127	4	study	study	NOUN
fnp-2955	127	5	has	have	AUX
fnp-2955	127	6	revealed	reveal	VERB
fnp-2955	127	7	generalised	generalised	ADJ
fnp-2955	127	8	changes	change	NOUN
fnp-2955	127	9	in	in	ADP
fnp-2955	127	10	the	the	DET
fnp-2955	127	11	white	white	ADJ
fnp-2955	127	12	matter	matter	NOUN
fnp-2955	127	13	in	in	ADP
fnp-2955	127	14	cases	case	NOUN
fnp-2955	127	15	of	of	ADP
fnp-2955	127	16	caa	caa	NOUN
fnp-2955	127	17	.	.	PUNCT
fnp-2955	128	1	thirdly	thirdly	ADV
fnp-2955	128	2	,	,	PUNCT
fnp-2955	128	3	we	we	PRON
fnp-2955	128	4	have	have	AUX
fnp-2955	128	5	not	not	PART
fnp-2955	128	6	performed	perform	VERB
fnp-2955	128	7	validation	validation	NOUN
fnp-2955	128	8	of	of	ADP
fnp-2955	128	9	the	the	DET
fnp-2955	128	10	results	result	NOUN
fnp-2955	128	11	by	by	ADP
fnp-2955	128	12	immunocytochemistry	immunocytochemistry	NOUN
fnp-2955	128	13	for	for	ADP
fnp-2955	128	14	the	the	DET
fnp-2955	128	15	proteins	protein	NOUN
fnp-2955	128	16	involved	involve	VERB
fnp-2955	128	17	.	.	PUNCT
fnp-2955	129	1	however	however	ADV
fnp-2955	129	2	,	,	PUNCT
fnp-2955	129	3	we	we	PRON
fnp-2955	129	4	have	have	AUX
fnp-2955	129	5	provided	provide	VERB
fnp-2955	129	6	evidence	evidence	NOUN
fnp-2955	129	7	from	from	ADP
fnp-2955	129	8	other	other	ADJ
fnp-2955	129	9	studies	study	NOUN
fnp-2955	129	10	that	that	PRON
fnp-2955	129	11	support	support	VERB
fnp-2955	129	12	our	our	PRON
fnp-2955	129	13	findings	finding	NOUN
fnp-2955	129	14	and	and	CCONJ
fnp-2955	129	15	provide	provide	VERB
fnp-2955	129	16	a	a	DET
fnp-2955	129	17	working	work	VERB
fnp-2955	129	18	hypothesis	hypothesis	NOUN
fnp-2955	129	19	.	.	PUNCT
fnp-2955	130	1	while	while	SCONJ
fnp-2955	130	2	previous	previous	ADJ
fnp-2955	130	3	proteomic	proteomic	ADJ
fnp-2955	130	4	studies	study	NOUN
fnp-2955	130	5	in	in	ADP
fnp-2955	130	6	the	the	DET
fnp-2955	130	7	white	white	ADJ
fnp-2955	130	8	matter	matter	NOUN
fnp-2955	130	9	in	in	ADP
fnp-2955	130	10	alzheimer	alzheimer	PROPN
fnp-2955	130	11	’s	’s	PART
fnp-2955	130	12	disease	disease	NOUN
fnp-2955	130	13	have	have	AUX
fnp-2955	130	14	identified	identify	VERB
fnp-2955	130	15	modifications	modification	NOUN
fnp-2955	130	16	in	in	ADP
fnp-2955	130	17	proteins	protein	NOUN
fnp-2955	130	18	that	that	PRON
fnp-2955	130	19	are	be	AUX
fnp-2955	130	20	involved	involve	VERB
fnp-2955	130	21	in	in	ADP
fnp-2955	130	22	cell	cell	NOUN
fnp-2955	130	23	survival	survival	NOUN
fnp-2955	130	24	and	and	CCONJ
fnp-2955	130	25	cell	cell	NOUN
fnp-2955	130	26	adhesion	adhesion	NOUN
fnp-2955	130	27	(	(	PUNCT
fnp-2955	130	28	22	22	NUM
fnp-2955	130	29	)	)	PUNCT
fnp-2955	130	30	,	,	PUNCT
fnp-2955	130	31	in	in	ADP
fnp-2955	130	32	our	our	PRON
fnp-2955	130	33	study	study	NOUN
fnp-2955	130	34	,	,	PUNCT
fnp-2955	130	35	we	we	PRON
fnp-2955	130	36	highlight	highlight	VERB
fnp-2955	130	37	that	that	SCONJ
fnp-2955	130	38	in	in	ADP
fnp-2955	130	39	the	the	DET
fnp-2955	130	40	white	white	ADJ
fnp-2955	130	41	matter	matter	NOUN
fnp-2955	130	42	of	of	ADP
fnp-2955	130	43	severe	severe	ADJ
fnp-2955	130	44	cases	case	NOUN
fnp-2955	130	45	of	of	ADP
fnp-2955	130	46	caa	caa	NOUN
fnp-2955	130	47	there	there	PRON
fnp-2955	130	48	is	be	VERB
fnp-2955	130	49	upregulation	upregulation	NOUN
fnp-2955	130	50	of	of	ADP
fnp-2955	130	51	the	the	DET
fnp-2955	130	52	proteins	protein	NOUN
fnp-2955	130	53	that	that	PRON
fnp-2955	130	54	mark	mark	VERB
fnp-2955	130	55	cell	cell	NOUN
fnp-2955	130	56	-	-	PUNCT
fnp-2955	130	57	matrix	matrix	NOUN
fnp-2955	130	58	interaction	interaction	NOUN
fnp-2955	130	59	,	,	PUNCT
fnp-2955	130	60	hypoxia	hypoxia	NOUN
fnp-2955	130	61	,	,	PUNCT
fnp-2955	130	62	mitochondrial	mitochondrial	ADJ
fnp-2955	130	63	dysfunction	dysfunction	NOUN
fnp-2955	130	64	and	and	CCONJ
fnp-2955	130	65	intramural	intramural	ADJ
fnp-2955	130	66	periarterial	periarterial	ADJ
fnp-2955	130	67	drainage	drainage	NOUN
fnp-2955	130	68	of	of	ADP
fnp-2955	130	69	soluble	soluble	ADJ
fnp-2955	130	70	aβ	aβ	NOUN
fnp-2955	130	71	.	.	PUNCT
fnp-2955	131	1	the	the	DET
fnp-2955	131	2	study	study	NOUN
fnp-2955	131	3	from	from	ADP
fnp-2955	131	4	castano	castano	PROPN
fnp-2955	131	5	et	et	PROPN
fnp-2955	131	6	al	al	PROPN
fnp-2955	131	7	in	in	ADP
fnp-2955	131	8	2013	2013	NUM
fnp-2955	131	9	used	use	VERB
fnp-2955	131	10	ad	ad	NOUN
fnp-2955	131	11	cases	case	NOUN
fnp-2955	131	12	with	with	ADP
fnp-2955	131	13	a	a	DET
fnp-2955	131	14	very	very	ADV
fnp-2955	131	15	low	low	ADJ
fnp-2955	131	16	caa	caa	NOUN
fnp-2955	131	17	score	score	NOUN
fnp-2955	131	18	(	(	PUNCT
fnp-2955	131	19	2	2	NUM
fnp-2955	131	20	out	out	ADP
fnp-2955	131	21	of	of	ADP
fnp-2955	131	22	a	a	DET
fnp-2955	131	23	maximum	maximum	NOUN
fnp-2955	131	24	of	of	ADP
fnp-2955	131	25	12	12	NUM
fnp-2955	131	26	)	)	PUNCT
fnp-2955	131	27	and	and	CCONJ
fnp-2955	131	28	identified	identify	VERB
fnp-2955	131	29	gfap	gfap	NOUN
fnp-2955	131	30	,	,	PUNCT
fnp-2955	131	31	tropomyosins	tropomyosin	NOUN
fnp-2955	131	32	,	,	PUNCT
fnp-2955	131	33	calmodulin	calmodulin	NOUN
fnp-2955	131	34	,	,	PUNCT
fnp-2955	131	35	annexin	annexin	NOUN
fnp-2955	131	36	1	1	NUM
fnp-2955	131	37	and	and	CCONJ
fnp-2955	131	38	alpha	alpha	NOUN
fnp-2955	131	39	-	-	NOUN
fnp-2955	131	40	internexin	internexin	NOUN
fnp-2955	131	41	as	as	SCONJ
fnp-2955	131	42	significantly	significantly	ADV
fnp-2955	131	43	upregulated	upregulate	VERB
fnp-2955	131	44	,	,	PUNCT
fnp-2955	131	45	while	while	SCONJ
fnp-2955	131	46	ubiquitin	ubiquitin	ADJ
fnp-2955	131	47	carboxyl	carboxyl	NOUN
fnp-2955	131	48	-	-	PUNCT
fnp-2955	131	49	terminal	terminal	ADJ
fnp-2955	131	50	esterase	esterase	NOUN
fnp-2955	131	51	and	and	CCONJ
fnp-2955	131	52	fascin-1	fascin-1	NUM
fnp-2955	131	53	were	be	AUX
fnp-2955	131	54	down	down	ADV
fnp-2955	131	55	-	-	PUNCT
fnp-2955	131	56	regulated	regulate	VERB
fnp-2955	131	57	(	(	PUNCT
fnp-2955	131	58	22	22	NUM
fnp-2955	131	59	)	)	PUNCT
fnp-2955	131	60	.	.	PUNCT
fnp-2955	132	1	the	the	DET
fnp-2955	132	2	upregulated	upregulated	ADJ
fnp-2955	132	3	proteins	protein	NOUN
fnp-2955	132	4	are	be	AUX
fnp-2955	132	5	part	part	NOUN
fnp-2955	132	6	of	of	ADP
fnp-2955	132	7	the	the	DET
fnp-2955	132	8	cytoskeleton	cytoskeleton	PROPN
fnp-2955	132	9	maintenance	maintenance	NOUN
fnp-2955	132	10	,	,	PUNCT
fnp-2955	132	11	calcium	calcium	NOUN
fnp-2955	132	12	metabolism	metabolism	NOUN
fnp-2955	132	13	and	and	CCONJ
fnp-2955	132	14	cell	cell	NOUN
fnp-2955	132	15	survival	survival	NOUN
fnp-2955	132	16	pathways	pathway	NOUN
fnp-2955	132	17	.	.	PUNCT
fnp-2955	133	1	we	we	PRON
fnp-2955	133	2	also	also	ADV
fnp-2955	133	3	have	have	AUX
fnp-2955	133	4	identified	identify	VERB
fnp-2955	133	5	annexin	annexin	NOUN
fnp-2955	133	6	and	and	CCONJ
fnp-2955	133	7	ubiquitin	ubiquitin	ADJ
fnp-2955	133	8	carboxyl	carboxyl	NOUN
fnp-2955	133	9	-	-	PUNCT
fnp-2955	133	10	terminal	terminal	ADJ
fnp-2955	133	11	esterase	esterase	NOUN
fnp-2955	133	12	modified	modify	VERB
fnp-2955	133	13	in	in	ADP
fnp-2955	133	14	the	the	DET
fnp-2955	133	15	same	same	ADJ
fnp-2955	133	16	pattern	pattern	NOUN
fnp-2955	133	17	.	.	PUNCT
fnp-2955	134	1	the	the	DET
fnp-2955	134	2	different	different	ADJ
fnp-2955	134	3	results	result	NOUN
fnp-2955	134	4	between	between	ADP
fnp-2955	134	5	the	the	DET
fnp-2955	134	6	two	two	NUM
fnp-2955	134	7	studies	study	NOUN
fnp-2955	134	8	are	be	AUX
fnp-2955	134	9	likely	likely	ADJ
fnp-2955	134	10	to	to	PART
fnp-2955	134	11	be	be	AUX
fnp-2955	134	12	due	due	ADJ
fnp-2955	134	13	to	to	ADP
fnp-2955	134	14	the	the	DET
fnp-2955	134	15	very	very	ADV
fnp-2955	134	16	different	different	ADJ
fnp-2955	134	17	caa	caa	NOUN
fnp-2955	134	18	status	status	NOUN
fnp-2955	134	19	of	of	ADP
fnp-2955	134	20	the	the	DET
fnp-2955	134	21	cases	case	NOUN
fnp-2955	134	22	;	;	PUNCT
fnp-2955	134	23	the	the	DET
fnp-2955	134	24	present	present	ADJ
fnp-2955	134	25	study	study	NOUN
fnp-2955	134	26	points	point	VERB
fnp-2955	134	27	to	to	ADP
fnp-2955	134	28	pathways	pathway	NOUN
fnp-2955	134	29	that	that	PRON
fnp-2955	134	30	are	be	AUX
fnp-2955	134	31	involved	involve	VERB
fnp-2955	134	32	in	in	ADP
fnp-2955	134	33	the	the	DET
fnp-2955	134	34	clearance	clearance	NOUN
fnp-2955	134	35	of	of	ADP
fnp-2955	134	36	aβ	aβ	PRON
fnp-2955	134	37	along	along	ADP
fnp-2955	134	38	the	the	DET
fnp-2955	134	39	vessel	vessel	NOUN
fnp-2955	134	40	walls	wall	NOUN
fnp-2955	134	41	.	.	PUNCT
fnp-2955	135	1	our	our	PRON
fnp-2955	135	2	results	result	NOUN
fnp-2955	135	3	suggest	suggest	VERB
fnp-2955	135	4	a	a	DET
fnp-2955	135	5	working	work	VERB
fnp-2955	135	6	hypothesis	hypothesis	NOUN
fnp-2955	135	7	that	that	SCONJ
fnp-2955	135	8	there	there	PRON
fnp-2955	135	9	is	be	VERB
fnp-2955	135	10	upregulation	upregulation	NOUN
fnp-2955	135	11	of	of	ADP
fnp-2955	135	12	the	the	DET
fnp-2955	135	13	intramural	intramural	ADJ
fnp-2955	135	14	periarterial	periarterial	ADJ
fnp-2955	135	15	drainage	drainage	NOUN
fnp-2955	135	16	(	(	PUNCT
fnp-2955	135	17	ipad	ipad	NOUN
fnp-2955	135	18	)	)	PUNCT
fnp-2955	135	19	pathways	pathway	NOUN
fnp-2955	135	20	in	in	ADP
fnp-2955	135	21	the	the	DET
fnp-2955	135	22	white	white	ADJ
fnp-2955	135	23	matter	matter	NOUN
fnp-2955	135	24	as	as	ADP
fnp-2955	135	25	a	a	DET
fnp-2955	135	26	compensatory	compensatory	ADJ
fnp-2955	135	27	mechanism	mechanism	NOUN
fnp-2955	135	28	to	to	ADP
fnp-2955	135	29	the	the	DET
fnp-2955	135	30	failure	failure	NOUN
fnp-2955	135	31	of	of	ADP
fnp-2955	135	32	drainage	drainage	NOUN
fnp-2955	135	33	of	of	ADP
fnp-2955	135	34	interstitial	interstitial	ADJ
fnp-2955	135	35	fluid	fluid	NOUN
fnp-2955	135	36	and	and	CCONJ
fnp-2955	135	37	solutes	solute	NOUN
fnp-2955	135	38	from	from	ADP
fnp-2955	135	39	the	the	DET
fnp-2955	135	40	white	white	ADJ
fnp-2955	135	41	matter	matter	NOUN
fnp-2955	135	42	and	and	CCONJ
fnp-2955	135	43	the	the	DET
fnp-2955	135	44	grey	grey	ADJ
fnp-2955	135	45	matter	matter	NOUN
fnp-2955	135	46	that	that	PRON
fnp-2955	135	47	is	be	AUX
fnp-2955	135	48	a	a	DET
fnp-2955	135	49	key	key	ADJ
fnp-2955	135	50	pathogenetic	pathogenetic	ADJ
fnp-2955	135	51	factor	factor	NOUN
fnp-2955	135	52	in	in	ADP
fnp-2955	135	53	caa	caa	NOUN
fnp-2955	135	54	.	.	PUNCT
fnp-2955	136	1	acknowledgments	acknowledgment	NOUN
fnp-2955	136	2	the	the	DET
fnp-2955	136	3	authors	author	NOUN
fnp-2955	136	4	thank	thank	VERB
fnp-2955	136	5	the	the	DET
fnp-2955	136	6	newcastle	newcastle	PROPN
fnp-2955	136	7	brain	brain	NOUN
fnp-2955	136	8	tissue	tissue	NOUN
fnp-2955	136	9	research	research	NOUN
fnp-2955	136	10	facility	facility	NOUN
fnp-2955	136	11	,	,	PUNCT
fnp-2955	136	12	the	the	DET
fnp-2955	136	13	patients	patient	NOUN
fnp-2955	136	14	and	and	CCONJ
fnp-2955	136	15	their	their	PRON
fnp-2955	136	16	families	family	NOUN
fnp-2955	136	17	.	.	PUNCT
fnp-2955	137	1	ethical	ethical	ADJ
fnp-2955	137	2	approval	approval	PROPN
fnp-2955	137	3	newcastle	newcastle	PROPN
fnp-2955	137	4	brain	brain	NOUN
fnp-2955	137	5	tissue	tissue	NOUN
fnp-2955	137	6	resource	resource	NOUN
fnp-2955	137	7	(	(	PUNCT
fnp-2955	137	8	ethics	ethic	NOUN
fnp-2955	137	9	rec	rec	X
fnp-2955	137	10	08	08	NUM
fnp-2955	137	11	/	/	SYM
fnp-2955	137	12	h0906/136	h0906/136	NOUN
fnp-2955	137	13	)	)	PUNCT
fnp-2955	137	14	.	.	PUNCT
fnp-2955	138	1	author	author	NOUN
fnp-2955	138	2	contributions	contribution	NOUN
fnp-2955	138	3	antigoni	antigoni	PROPN
fnp-2955	138	4	manousopoulou	manousopoulou	PROPN
fnp-2955	138	5	performed	perform	VERB
fnp-2955	138	6	the	the	DET
fnp-2955	138	7	proteomic	proteomic	ADJ
fnp-2955	138	8	experiments	experiment	NOUN
fnp-2955	138	9	,	,	PUNCT
fnp-2955	138	10	analysed	analyse	VERB
fnp-2955	138	11	data	datum	NOUN
fnp-2955	138	12	,	,	PUNCT
fnp-2955	138	13	interpreted	interpret	VERB
fnp-2955	138	14	data	datum	NOUN
fnp-2955	138	15	and	and	CCONJ
fnp-2955	138	16	wrote	write	VERB
fnp-2955	138	17	manuscript	manuscript	NOUN
fnp-2955	138	18	;	;	PUNCT
fnp-2955	138	19	roxana	roxana	PROPN
fnp-2955	138	20	o.	o.	PROPN
fnp-2955	138	21	carare	carare	PROPN
fnp-2955	138	22	and	and	CCONJ
fnp-2955	138	23	spiros	spiros	PROPN
fnp-2955	138	24	d.	d.	PROPN
fnp-2955	138	25	garbis	garbis	PROPN
fnp-2955	138	26	designed	design	VERB
fnp-2955	138	27	the	the	DET
fnp-2955	138	28	study	study	NOUN
fnp-2955	138	29	;	;	PUNCT
fnp-2955	138	30	ho	ho	PROPN
fnp-2955	138	31	ming	ming	PROPN
fnp-2955	138	32	yuen	yuen	PROPN
fnp-2955	138	33	assisted	assist	VERB
fnp-2955	138	34	with	with	ADP
fnp-2955	138	35	statistical	statistical	ADJ
fnp-2955	138	36	analysis	analysis	NOUN
fnp-2955	138	37	;	;	PUNCT
fnp-2955	138	38	matthew	matthew	PROPN
fnp-2955	138	39	macgregor	macgregor	PROPN
fnp-2955	138	40	sharp	sharp	PROPN
fnp-2955	138	41	,	,	PUNCT
fnp-2955	138	42	satoshi	satoshi	PROPN
fnp-2955	138	43	saito	saito	PROPN
fnp-2955	138	44	,	,	PUNCT
fnp-2955	138	45	norman	norman	PROPN
fnp-2955	138	46	mazer	mazer	PROPN
fnp-2955	138	47	and	and	CCONJ
fnp-2955	138	48	roxana	roxana	PROPN
fnp-2955	138	49	aldea	aldea	PROPN
fnp-2955	138	50	had	have	VERB
fnp-2955	138	51	important	important	ADJ
fnp-2955	138	52	intellectual	intellectual	ADJ
fnp-2955	138	53	contributions	contribution	NOUN
fnp-2955	138	54	to	to	ADP
fnp-2955	138	55	the	the	DET
fnp-2955	138	56	design	design	NOUN
fnp-2955	138	57	of	of	ADP
fnp-2955	138	58	the	the	DET
fnp-2955	138	59	study	study	NOUN
fnp-2955	138	60	and	and	CCONJ
fnp-2955	138	61	analysis	analysis	NOUN
fnp-2955	138	62	.	.	PUNCT
fnp-2955	139	1	references	reference	NOUN
fnp-2955	139	2	1	1	NUM
fnp-2955	139	3	.	.	PUNCT
fnp-2955	140	1	jellinger	jellinger	PROPN
fnp-2955	140	2	ka	ka	PROPN
fnp-2955	140	3	,	,	PUNCT
fnp-2955	140	4	attems	attem	VERB
fnp-2955	140	5	j.	j.	PROPN
fnp-2955	140	6	prevalence	prevalence	PROPN
fnp-2955	140	7	and	and	CCONJ
fnp-2955	140	8	pathogenic	pathogenic	ADJ
fnp-2955	140	9	role	role	NOUN
fnp-2955	140	10	of	of	ADP
fnp-2955	140	11	cerebrovascular	cerebrovascular	ADJ
fnp-2955	140	12	lesions	lesion	NOUN
fnp-2955	140	13	in	in	ADP
fnp-2955	140	14	alzheimer	alzheimer	PROPN
fnp-2955	140	15	disease	disease	NOUN
fnp-2955	140	16	1	1	NUM
fnp-2955	140	17	.	.	PUNCT
fnp-2955	141	1	j	j	PROPN
fnp-2955	141	2	neurolsci	neurolsci	PROPN
fnp-2955	141	3	.	.	PUNCT
fnp-2955	142	1	2005;229	2005;229	NUM
fnp-2955	142	2	-	-	PUNCT
fnp-2955	142	3	230:37	230:37	PROPN
fnp-2955	142	4	-	-	PUNCT
fnp-2955	142	5	41	41	NUM
fnp-2955	142	6	.	.	NOUN
fnp-2955	143	1	2	2	NUM
fnp-2955	143	2	.	.	X
fnp-2955	143	3	banerjee	banerjee	PROPN
fnp-2955	143	4	g	g	PROPN
fnp-2955	143	5	,	,	PUNCT
fnp-2955	143	6	carare	carare	NOUN
fnp-2955	143	7	r	r	NOUN
fnp-2955	143	8	,	,	PUNCT
fnp-2955	143	9	cordonnier	cordonnier	NOUN
fnp-2955	143	10	c	c	NOUN
fnp-2955	143	11	,	,	PUNCT
fnp-2955	143	12	greenberg	greenberg	PROPN
fnp-2955	143	13	sm	sm	PROPN
fnp-2955	143	14	,	,	PUNCT
fnp-2955	143	15	schneider	schneider	PROPN
fnp-2955	143	16	ja	ja	PROPN
fnp-2955	143	17	,	,	PUNCT
fnp-2955	143	18	smith	smith	PROPN
fnp-2955	143	19	ee	ee	PROPN
fnp-2955	143	20	,	,	PUNCT
fnp-2955	143	21	et	et	PROPN
fnp-2955	143	22	al	al	PROPN
fnp-2955	143	23	.	.	PUNCT
fnp-2955	144	1	the	the	DET
fnp-2955	144	2	increasing	increase	VERB
fnp-2955	144	3	impact	impact	NOUN
fnp-2955	144	4	of	of	ADP
fnp-2955	144	5	cerebral	cerebral	ADJ
fnp-2955	144	6	amyloid	amyloid	NOUN
fnp-2955	144	7	angiopathy	angiopathy	NOUN
fnp-2955	144	8	:	:	PUNCT
fnp-2955	144	9	essential	essential	ADJ
fnp-2955	144	10	new	new	ADJ
fnp-2955	144	11	insights	insight	NOUN
fnp-2955	144	12	for	for	ADP
fnp-2955	144	13	clinical	clinical	ADJ
fnp-2955	144	14	practice	practice	NOUN
fnp-2955	144	15	.	.	PUNCT
fnp-2955	145	1	j	j	PROPN
fnp-2955	145	2	neurol	neurol	PROPN
fnp-2955	145	3	neurosurg	neurosurg	PROPN
fnp-2955	145	4	psychiatry	psychiatry	PROPN
fnp-2955	145	5	.	.	PUNCT
fnp-2955	145	6	.	.	PUNCT
fnp-2955	146	1	2017;88(11):982	2017;88(11):982	NUM
fnp-2955	146	2	-	-	SYM
fnp-2955	146	3	94	94	NUM
fnp-2955	146	4	.	.	PUNCT
fnp-2955	147	1	3	3	X
fnp-2955	147	2	.	.	X
fnp-2955	147	3	schreiber	schreiber	PROPN
fnp-2955	147	4	s	s	PART
fnp-2955	147	5	,	,	PUNCT
fnp-2955	147	6	wilisch	wilisch	ADV
fnp-2955	147	7	-	-	PUNCT
fnp-2955	147	8	neumann	neumann	PROPN
fnp-2955	147	9	a	a	PROPN
fnp-2955	147	10	,	,	PUNCT
fnp-2955	147	11	schreiber	schreiber	PROPN
fnp-2955	147	12	f	f	PROPN
fnp-2955	147	13	,	,	PUNCT
fnp-2955	147	14	assmann	assmann	PROPN
fnp-2955	147	15	a	a	PROPN
fnp-2955	147	16	,	,	PUNCT
fnp-2955	147	17	scheumann	scheumann	PROPN
fnp-2955	147	18	v	v	NOUN
fnp-2955	147	19	,	,	PUNCT
fnp-2955	147	20	perosa	perosa	PROPN
fnp-2955	147	21	v	v	NOUN
fnp-2955	147	22	,	,	PUNCT
fnp-2955	147	23	et	et	PROPN
fnp-2955	147	24	al	al	PROPN
fnp-2955	147	25	.	.	PROPN
fnp-2955	147	26	invited	invite	VERB
fnp-2955	147	27	review	review	NOUN
fnp-2955	147	28	:	:	PUNCT
fnp-2955	147	29	the	the	DET
fnp-2955	147	30	spectrum	spectrum	NOUN
fnp-2955	147	31	of	of	ADP
fnp-2955	147	32	age	age	NOUN
fnp-2955	147	33	-	-	PUNCT
fnp-2955	147	34	related	relate	VERB
fnp-2955	147	35	small	small	ADJ
fnp-2955	147	36	vessel	vessel	NOUN
fnp-2955	147	37	diseases	disease	NOUN
fnp-2955	147	38	:	:	PUNCT
fnp-2955	147	39	potential	potential	ADJ
fnp-2955	147	40	overlap	overlap	NOUN
fnp-2955	147	41	and	and	CCONJ
fnp-2955	147	42	interactions	interaction	NOUN
fnp-2955	147	43	of	of	ADP
fnp-2955	147	44	amyloid	amyloid	NOUN
fnp-2955	147	45	and	and	CCONJ
fnp-2955	147	46	nonamyloid	nonamyloid	NOUN
fnp-2955	147	47	vasculopathies	vasculopathie	NOUN
fnp-2955	147	48	.	.	PUNCT
fnp-2955	148	1	neuropathol	neuropathol	NOUN
fnp-2955	148	2	appl	appl	PROPN
fnp-2955	148	3	neurobiol	neurobiol	PROPN
fnp-2955	148	4	.	.	PUNCT
fnp-2955	149	1	2020;46(3):219	2020;46(3):219	NUM
fnp-2955	149	2	-	-	SYM
fnp-2955	149	3	239	239	NUM
fnp-2955	149	4	.	.	PUNCT
fnp-2955	150	1	4	4	NUM
fnp-2955	150	2	.	.	X
fnp-2955	150	3	carare	carare	PROPN
fnp-2955	150	4	ro	ro	PROPN
fnp-2955	150	5	,	,	PUNCT
fnp-2955	150	6	hawkes	hawkes	PROPN
fnp-2955	150	7	ca	can	AUX
fnp-2955	150	8	,	,	PUNCT
fnp-2955	150	9	jeffrey	jeffrey	PROPN
fnp-2955	150	10	m	m	PROPN
fnp-2955	150	11	,	,	PUNCT
fnp-2955	150	12	kalaria	kalaria	PROPN
fnp-2955	150	13	rn	rn	PROPN
fnp-2955	150	14	,	,	PUNCT
fnp-2955	150	15	weller	weller	PROPN
fnp-2955	150	16	ro	ro	PROPN
fnp-2955	150	17	.	.	PROPN
fnp-2955	151	1	review	review	PROPN
fnp-2955	151	2	:	:	PUNCT
fnp-2955	151	3	cerebral	cerebral	ADJ
fnp-2955	151	4	amyloid	amyloid	NOUN
fnp-2955	151	5	angiopathy	angiopathy	NOUN
fnp-2955	151	6	,	,	PUNCT
fnp-2955	151	7	prion	prion	NOUN
fnp-2955	151	8	angiopathy	angiopathy	NOUN
fnp-2955	151	9	,	,	PUNCT
fnp-2955	151	10	cadasil	cadasil	NOUN
fnp-2955	151	11	and	and	CCONJ
fnp-2955	151	12	the	the	DET
fnp-2955	151	13	spectrum	spectrum	NOUN
fnp-2955	151	14	of	of	ADP
fnp-2955	151	15	protein	protein	NOUN
fnp-2955	151	16	elimination	elimination	NOUN
fnp-2955	151	17	failure	failure	NOUN
fnp-2955	151	18	angiopathies	angiopathy	NOUN
fnp-2955	151	19	(	(	PUNCT
fnp-2955	151	20	pefa	pefa	PROPN
fnp-2955	151	21	)	)	PUNCT
fnp-2955	151	22	in	in	ADP
fnp-2955	151	23	neurodegenerative	neurodegenerative	ADJ
fnp-2955	151	24	disease	disease	NOUN
fnp-2955	151	25	with	with	ADP
fnp-2955	151	26	a	a	DET
fnp-2955	151	27	focus	focus	NOUN
fnp-2955	151	28	on	on	ADP
fnp-2955	151	29	therapy	therapy	NOUN
fnp-2955	151	30	.	.	PUNCT
fnp-2955	152	1	neuropathol	neuropathol	PROPN
fnp-2955	152	2	appl	appl	PROPN
fnp-2955	152	3	neurobio	neurobio	PROPN
fnp-2955	152	4	.	.	PUNCT
fnp-2955	153	1	2013;39(6):593	2013;39(6):593	NUM
fnp-2955	153	2	-	-	SYM
fnp-2955	153	3	611	611	NUM
fnp-2955	153	4	.	.	PUNCT
fnp-2955	154	1	5	5	X
fnp-2955	154	2	.	.	PUNCT
fnp-2955	154	3	weller	weller	PROPN
fnp-2955	154	4	ro	ro	PROPN
fnp-2955	154	5	,	,	PUNCT
fnp-2955	154	6	hawkes	hawkes	PROPN
fnp-2955	154	7	ca	can	AUX
fnp-2955	154	8	,	,	PUNCT
fnp-2955	154	9	kalaria	kalaria	PROPN
fnp-2955	154	10	rn	rn	PROPN
fnp-2955	154	11	,	,	PUNCT
fnp-2955	154	12	werring	werring	NOUN
fnp-2955	154	13	dj	dj	NOUN
fnp-2955	154	14	,	,	PUNCT
fnp-2955	154	15	carare	carare	PROPN
fnp-2955	154	16	ro	ro	X
fnp-2955	154	17	.	.	PROPN
fnp-2955	154	18	white	white	PROPN
fnp-2955	154	19	matter	matter	NOUN
fnp-2955	154	20	changes	change	NOUN
fnp-2955	154	21	in	in	ADP
fnp-2955	154	22	dementia	dementia	NOUN
fnp-2955	154	23	:	:	PUNCT
fnp-2955	154	24	role	role	NOUN
fnp-2955	154	25	of	of	ADP
fnp-2955	154	26	impaired	impaired	ADJ
fnp-2955	154	27	drainage	drainage	NOUN
fnp-2955	154	28	of	of	ADP
fnp-2955	154	29	interstitial	interstitial	ADJ
fnp-2955	154	30	fluid	fluid	NOUN
fnp-2955	154	31	.	.	PUNCT
fnp-2955	155	1	brain	brain	NOUN
fnp-2955	155	2	pathol	pathol	NOUN
fnp-2955	155	3	.	.	PUNCT
fnp-2955	156	1	2015;25(1):63	2015;25(1):63	NUM
fnp-2955	156	2	-	-	SYM
fnp-2955	156	3	78	78	NUM
fnp-2955	156	4	.	.	PUNCT
fnp-2955	157	1	6	6	NUM
fnp-2955	157	2	.	.	X
fnp-2955	157	3	revesz	revesz	PROPN
fnp-2955	157	4	t	t	PROPN
fnp-2955	157	5	,	,	PUNCT
fnp-2955	157	6	holton	holton	PROPN
fnp-2955	157	7	jl	jl	PROPN
fnp-2955	157	8	,	,	PUNCT
fnp-2955	157	9	lashley	lashley	PROPN
fnp-2955	157	10	t	t	PROPN
fnp-2955	157	11	,	,	PUNCT
fnp-2955	157	12	plant	plant	NOUN
fnp-2955	157	13	g	g	NOUN
fnp-2955	157	14	,	,	PUNCT
fnp-2955	157	15	frangione	frangione	NOUN
fnp-2955	157	16	b	b	PROPN
fnp-2955	157	17	,	,	PUNCT
fnp-2955	157	18	rostagno	rostagno	NOUN
fnp-2955	157	19	a	a	X
fnp-2955	157	20	,	,	PUNCT
fnp-2955	157	21	et	et	PROPN
fnp-2955	157	22	al	al	PROPN
fnp-2955	157	23	.	.	PUNCT
fnp-2955	157	24	genetics	genetic	NOUN
fnp-2955	157	25	and	and	CCONJ
fnp-2955	157	26	molecular	molecular	ADJ
fnp-2955	157	27	pathogenesis	pathogenesis	NOUN
fnp-2955	157	28	of	of	ADP
fnp-2955	157	29	sporadic	sporadic	ADJ
fnp-2955	157	30	and	and	CCONJ
fnp-2955	157	31	hereditary	hereditary	ADJ
fnp-2955	157	32	cerebral	cerebral	ADJ
fnp-2955	157	33	amyloid	amyloid	NOUN
fnp-2955	157	34	angiopathies	angiopathy	NOUN
fnp-2955	157	35	.	.	PUNCT
fnp-2955	158	1	acta	acta	PROPN
fnp-2955	158	2	neuropathol	neuropathol	PROPN
fnp-2955	158	3	.	.	PUNCT
fnp-2955	159	1	2009;118(1):115	2009;118(1):115	NUM
fnp-2955	159	2	-	-	SYM
fnp-2955	159	3	30	30	NUM
fnp-2955	159	4	.	.	PUNCT
fnp-2955	160	1	7	7	X
fnp-2955	160	2	.	.	X
fnp-2955	160	3	maniega	maniega	PROPN
fnp-2955	160	4	sm	sm	PROPN
fnp-2955	160	5	,	,	PUNCT
fnp-2955	160	6	valdes	valdes	PROPN
fnp-2955	160	7	hernandez	hernandez	PROPN
fnp-2955	160	8	mc	mc	PROPN
fnp-2955	160	9	,	,	PUNCT
fnp-2955	160	10	clayden	clayden	PROPN
fnp-2955	160	11	jd	jd	PROPN
fnp-2955	160	12	,	,	PUNCT
fnp-2955	160	13	royle	royle	PROPN
fnp-2955	160	14	na	na	PROPN
fnp-2955	160	15	,	,	PUNCT
fnp-2955	160	16	murray	murray	PROPN
fnp-2955	160	17	c	c	PROPN
fnp-2955	160	18	,	,	PUNCT
fnp-2955	160	19	morris	morris	PROPN
fnp-2955	160	20	z	z	PROPN
fnp-2955	160	21	,	,	PUNCT
fnp-2955	160	22	et	et	PROPN
fnp-2955	160	23	al	al	PROPN
fnp-2955	160	24	.	.	PROPN
fnp-2955	160	25	white	white	PROPN
fnp-2955	160	26	matter	matter	PROPN
fnp-2955	160	27	hyperintensities	hyperintensitie	NOUN
fnp-2955	160	28	and	and	CCONJ
fnp-2955	160	29	normal	normal	ADJ
fnp-2955	160	30	-	-	PUNCT
fnp-2955	160	31	appearing	appear	VERB
fnp-2955	160	32	white	white	ADJ
fnp-2955	160	33	matter	matter	NOUN
fnp-2955	160	34	integrity	integrity	NOUN
fnp-2955	160	35	in	in	ADP
fnp-2955	160	36	the	the	DET
fnp-2955	160	37	aging	age	VERB
fnp-2955	160	38	brain	brain	NOUN
fnp-2955	160	39	.	.	PUNCT
fnp-2955	161	1	neurobiol	neurobiol	PROPN
fnp-2955	161	2	aging	aging	NOUN
fnp-2955	161	3	.	.	PUNCT
fnp-2955	162	1	2015;36(2):909	2015;36(2):909	NUM
fnp-2955	162	2	-	-	SYM
fnp-2955	162	3	18	18	NUM
fnp-2955	162	4	.	.	NOUN
fnp-2955	162	5	8	8	NUM
fnp-2955	162	6	.	.	X
fnp-2955	162	7	wardlaw	wardlaw	PROPN
fnp-2955	162	8	jm	jm	PROPN
fnp-2955	162	9	,	,	PUNCT
fnp-2955	162	10	benveniste	benveniste	VERB
fnp-2955	162	11	h	h	NOUN
fnp-2955	162	12	,	,	PUNCT
fnp-2955	162	13	nedergaard	nedergaard	PROPN
fnp-2955	162	14	m	m	PROPN
fnp-2955	162	15	,	,	PUNCT
fnp-2955	162	16	zlokovic	zlokovic	PROPN
fnp-2955	162	17	bv	bv	PROPN
fnp-2955	162	18	,	,	PUNCT
fnp-2955	162	19	mestre	mestre	PROPN
fnp-2955	162	20	h	h	PROPN
fnp-2955	162	21	,	,	PUNCT
fnp-2955	162	22	lee	lee	PROPN
fnp-2955	162	23	h	h	PROPN
fnp-2955	162	24	,	,	PUNCT
fnp-2955	162	25	et	et	PROPN
fnp-2955	162	26	al	al	PROPN
fnp-2955	162	27	.	.	PUNCT
fnp-2955	163	1	perivascular	perivascular	ADJ
fnp-2955	163	2	spaces	space	NOUN
fnp-2955	163	3	in	in	ADP
fnp-2955	163	4	the	the	DET
fnp-2955	163	5	brain	brain	NOUN
fnp-2955	163	6	:	:	PUNCT
fnp-2955	163	7	anatomy	anatomy	NOUN
fnp-2955	163	8	,	,	PUNCT
fnp-2955	163	9	physiology	physiology	NOUN
fnp-2955	163	10	and	and	CCONJ
fnp-2955	163	11	pathology	pathology	NOUN
fnp-2955	163	12	.	.	PUNCT
fnp-2955	164	1	nat	nat	PROPN
fnp-2955	164	2	rev	rev	VERB
fnp-2955	164	3	neurol	neurol	PROPN
fnp-2955	164	4	.	.	PUNCT
fnp-2955	165	1	2020;16(3):137	2020;16(3):137	NUM
fnp-2955	165	2	-	-	SYM
fnp-2955	165	3	53	53	NUM
fnp-2955	165	4	.	.	NOUN
fnp-2955	165	5	9	9	NUM
fnp-2955	165	6	.	.	X
fnp-2955	166	1	al	al	PROPN
fnp-2955	166	2	-	-	PUNCT
fnp-2955	166	3	mashhadi	mashhadi	PROPN
fnp-2955	166	4	s	s	PROPN
fnp-2955	166	5	,	,	PUNCT
fnp-2955	166	6	simpson	simpson	PROPN
fnp-2955	166	7	je	je	PROPN
fnp-2955	166	8	,	,	PUNCT
fnp-2955	166	9	heath	heath	PROPN
fnp-2955	166	10	pr	pr	PROPN
fnp-2955	166	11	,	,	PUNCT
fnp-2955	166	12	dickman	dickman	PROPN
fnp-2955	166	13	m	m	PROPN
fnp-2955	166	14	,	,	PUNCT
fnp-2955	166	15	forster	forster	PROPN
fnp-2955	166	16	g	g	PROPN
fnp-2955	166	17	,	,	PUNCT
fnp-2955	166	18	matthews	matthews	PROPN
fnp-2955	166	19	fe	fe	PROPN
fnp-2955	166	20	,	,	PUNCT
fnp-2955	166	21	et	et	PROPN
fnp-2955	166	22	al	al	PROPN
fnp-2955	166	23	.	.	PROPN
fnp-2955	167	1	oxidative	oxidative	ADJ
fnp-2955	167	2	glial	glial	ADJ
fnp-2955	167	3	cell	cell	NOUN
fnp-2955	167	4	damage	damage	NOUN
fnp-2955	167	5	associated	associate	VERB
fnp-2955	167	6	with	with	ADP
fnp-2955	167	7	white	white	ADJ
fnp-2955	167	8	matter	matter	NOUN
fnp-2955	167	9	lesions	lesion	NOUN
fnp-2955	167	10	in	in	ADP
fnp-2955	167	11	the	the	DET
fnp-2955	167	12	aging	age	VERB
fnp-2955	167	13	human	human	ADJ
fnp-2955	167	14	brain	brain	NOUN
fnp-2955	167	15	.	.	PUNCT
fnp-2955	168	1	brain	brain	NOUN
fnp-2955	168	2	pathol	pathol	NOUN
fnp-2955	168	3	.	.	PUNCT
fnp-2955	169	1	2015;25(5):565	2015;25(5):565	NUM
fnp-2955	169	2	-	-	SYM
fnp-2955	169	3	74	74	NUM
fnp-2955	169	4	.	.	PUNCT
fnp-2955	170	1	10	10	NUM
fnp-2955	170	2	.	.	PUNCT
fnp-2955	171	1	chen	chen	PROPN
fnp-2955	171	2	a	a	DET
fnp-2955	171	3	,	,	PUNCT
fnp-2955	171	4	akinyemi	akinyemi	PROPN
fnp-2955	171	5	ro	ro	PROPN
fnp-2955	171	6	,	,	PUNCT
fnp-2955	171	7	hase	hase	VERB
fnp-2955	171	8	y	y	PROPN
fnp-2955	171	9	,	,	PUNCT
fnp-2955	171	10	firbank	firbank	PROPN
fnp-2955	171	11	mj	mj	PROPN
fnp-2955	171	12	,	,	PUNCT
fnp-2955	171	13	ndung'u	ndung'u	PROPN
fnp-2955	171	14	mn	mn	PROPN
fnp-2955	171	15	,	,	PUNCT
fnp-2955	171	16	foster	foster	ADJ
fnp-2955	171	17	v	v	NOUN
fnp-2955	171	18	,	,	PUNCT
fnp-2955	171	19	et	et	PROPN
fnp-2955	171	20	al	al	PROPN
fnp-2955	171	21	.	.	PROPN
fnp-2955	172	1	frontal	frontal	ADJ
fnp-2955	172	2	white	white	ADJ
fnp-2955	172	3	matter	matter	NOUN
fnp-2955	172	4	hyperintensities	hyperintensitie	NOUN
fnp-2955	172	5	,	,	PUNCT
fnp-2955	172	6	clasmatodendrosis	clasmatodendrosis	NOUN
fnp-2955	172	7	and	and	CCONJ
fnp-2955	172	8	gliovascular	gliovascular	ADJ
fnp-2955	172	9	abnormalities	abnormality	NOUN
fnp-2955	172	10	in	in	ADP
fnp-2955	172	11	ageing	age	VERB
fnp-2955	172	12	and	and	CCONJ
fnp-2955	172	13	post	post	ADJ
fnp-2955	172	14	-	-	ADJ
fnp-2955	172	15	stroke	stroke	ADJ
fnp-2955	172	16	dementia	dementia	NOUN
fnp-2955	172	17	.	.	PUNCT
fnp-2955	173	1	brain	brain	NOUN
fnp-2955	173	2	.	.	PUNCT
fnp-2955	174	1	2016;139(pt	2016;139(pt	PROPN
fnp-2955	174	2	1):242	1):242	PROPN
fnp-2955	174	3	-	-	SYM
fnp-2955	174	4	58	58	NUM
fnp-2955	174	5	.	.	PUNCT
fnp-2955	175	1	11	11	NUM
fnp-2955	175	2	.	.	X
fnp-2955	176	1	wardlaw	wardlaw	PROPN
fnp-2955	176	2	jm	jm	PROPN
fnp-2955	176	3	,	,	PUNCT
fnp-2955	176	4	valdes	valdes	PROPN
fnp-2955	176	5	hernandez	hernandez	PROPN
fnp-2955	176	6	mc	mc	PROPN
fnp-2955	176	7	,	,	PUNCT
fnp-2955	176	8	munoz	munoz	PROPN
fnp-2955	176	9	-	-	PUNCT
fnp-2955	176	10	maniega	maniega	PROPN
fnp-2955	176	11	s.	s.	PROPN
fnp-2955	176	12	what	what	PRON
fnp-2955	176	13	are	be	AUX
fnp-2955	176	14	white	white	ADJ
fnp-2955	176	15	matter	matter	NOUN
fnp-2955	176	16	hyperintensities	hyperintensitie	NOUN
fnp-2955	176	17	made	make	VERB
fnp-2955	176	18	of	of	ADP
fnp-2955	176	19	?	?	PUNCT
fnp-2955	176	20	relevance	relevance	NOUN
fnp-2955	176	21	to	to	PART
fnp-2955	176	22	vascular	vascular	VERB
fnp-2955	176	23	cognitive	cognitive	ADJ
fnp-2955	176	24	impairment	impairment	NOUN
fnp-2955	176	25	.	.	PUNCT
fnp-2955	177	1	j	j	PROPN
fnp-2955	177	2	am	be	AUX
fnp-2955	177	3	heart	heart	NOUN
fnp-2955	177	4	assoc	assoc	NOUN
fnp-2955	177	5	.	.	PUNCT
fnp-2955	178	1	2015;4(6	2015;4(6	NUM
fnp-2955	178	2	)	)	PUNCT
fnp-2955	178	3	.	.	PUNCT
fnp-2955	179	1	12	12	NUM
fnp-2955	179	2	.	.	PUNCT
fnp-2955	180	1	morris	morris	PROPN
fnp-2955	180	2	aw	aw	INTJ
fnp-2955	180	3	,	,	PUNCT
fnp-2955	180	4	sharp	sharp	PROPN
fnp-2955	180	5	mm	mm	PROPN
fnp-2955	180	6	,	,	PUNCT
fnp-2955	180	7	albargothy	albargothy	PROPN
fnp-2955	180	8	nj	nj	PROPN
fnp-2955	180	9	,	,	PUNCT
fnp-2955	180	10	fernandes	fernandes	PROPN
fnp-2955	180	11	r	r	PROPN
fnp-2955	180	12	,	,	PUNCT
fnp-2955	180	13	hawkes	hawke	NOUN
fnp-2955	180	14	ca	can	AUX
fnp-2955	180	15	,	,	PUNCT
fnp-2955	180	16	verma	verma	PROPN
fnp-2955	180	17	a	a	PROPN
fnp-2955	180	18	,	,	PUNCT
fnp-2955	180	19	et	et	PROPN
fnp-2955	180	20	al	al	PROPN
fnp-2955	180	21	.	.	PROPN
fnp-2955	180	22	vascular	vascular	ADJ
fnp-2955	180	23	basement	basement	NOUN
fnp-2955	180	24	membranes	membrane	NOUN
fnp-2955	180	25	as	as	ADP
fnp-2955	180	26	pathways	pathway	NOUN
fnp-2955	180	27	for	for	ADP
fnp-2955	180	28	the	the	DET
fnp-2955	180	29	passage	passage	NOUN
fnp-2955	180	30	of	of	ADP
fnp-2955	180	31	fluid	fluid	NOUN
fnp-2955	180	32	into	into	ADP
fnp-2955	180	33	and	and	CCONJ
fnp-2955	180	34	out	out	ADP
fnp-2955	180	35	of	of	ADP
fnp-2955	180	36	the	the	DET
fnp-2955	180	37	brain	brain	NOUN
fnp-2955	180	38	.	.	PUNCT
fnp-2955	181	1	acta	acta	PROPN
fnp-2955	181	2	neuropathol	neuropathol	PROPN
fnp-2955	181	3	.	.	PUNCT
fnp-2955	182	1	2016;131(5):725	2016;131(5):725	NUM
fnp-2955	182	2	-	-	SYM
fnp-2955	182	3	36	36	NUM
fnp-2955	182	4	.	.	NOUN
fnp-2955	182	5	13	13	NUM
fnp-2955	182	6	.	.	X
fnp-2955	183	1	albargothy	albargothy	PROPN
fnp-2955	183	2	nj	nj	PROPN
fnp-2955	183	3	,	,	PUNCT
fnp-2955	183	4	johnston	johnston	PROPN
fnp-2955	183	5	da	da	PROPN
fnp-2955	183	6	,	,	PUNCT
fnp-2955	183	7	macgregor	macgregor	PROPN
fnp-2955	183	8	-	-	PUNCT
fnp-2955	183	9	sharp	sharp	PROPN
fnp-2955	183	10	m	m	PROPN
fnp-2955	183	11	,	,	PUNCT
fnp-2955	183	12	weller	weller	PROPN
fnp-2955	183	13	ro	ro	PROPN
fnp-2955	183	14	,	,	PUNCT
fnp-2955	183	15	verma	verma	PROPN
fnp-2955	183	16	a	a	PROPN
fnp-2955	183	17	,	,	PUNCT
fnp-2955	183	18	hawkes	hawkes	PROPN
fnp-2955	183	19	ca	can	AUX
fnp-2955	183	20	,	,	PUNCT
fnp-2955	183	21	et	et	PROPN
fnp-2955	183	22	al	al	PROPN
fnp-2955	183	23	.	.	PUNCT
fnp-2955	183	24	convective	convective	ADJ
fnp-2955	183	25	influx	influx	NOUN
fnp-2955	183	26	/	/	SYM
fnp-2955	183	27	glymphatic	glymphatic	ADJ
fnp-2955	183	28	system	system	NOUN
fnp-2955	183	29	:	:	PUNCT
fnp-2955	183	30	tracers	tracer	NOUN
fnp-2955	183	31	injected	inject	VERB
fnp-2955	183	32	into	into	ADP
fnp-2955	183	33	the	the	DET
fnp-2955	183	34	csf	csf	NOUN
fnp-2955	183	35	enter	enter	VERB
fnp-2955	183	36	and	and	CCONJ
fnp-2955	183	37	leave	leave	VERB
fnp-2955	183	38	the	the	DET
fnp-2955	183	39	brain	brain	NOUN
fnp-2955	183	40	along	along	ADP
fnp-2955	183	41	separate	separate	ADJ
fnp-2955	183	42	periarterial	periarterial	ADJ
fnp-2955	183	43	basement	basement	NOUN
fnp-2955	183	44	membrane	membrane	NOUN
fnp-2955	183	45	pathways	pathway	NOUN
fnp-2955	183	46	.	.	PUNCT
fnp-2955	184	1	acta	acta	PROPN
fnp-2955	184	2	neuropathol	neuropathol	PROPN
fnp-2955	184	3	.	.	PUNCT
fnp-2955	185	1	2018;136(1):139	2018;136(1):139	NUM
fnp-2955	185	2	-	-	SYM
fnp-2955	185	3	152	152	NUM
fnp-2955	185	4	.	.	PUNCT
fnp-2955	186	1	14	14	NUM
fnp-2955	186	2	.	.	PUNCT
fnp-2955	187	1	hawkes	hawke	NOUN
fnp-2955	187	2	ca	can	AUX
fnp-2955	187	3	,	,	PUNCT
fnp-2955	187	4	hartig	hartig	PROPN
fnp-2955	187	5	w	w	PROPN
fnp-2955	187	6	,	,	PUNCT
fnp-2955	187	7	kacza	kacza	PROPN
fnp-2955	187	8	j	j	PROPN
fnp-2955	187	9	,	,	PUNCT
fnp-2955	187	10	schliebs	schliebs	ADJ
fnp-2955	187	11	r	r	NOUN
fnp-2955	187	12	,	,	PUNCT
fnp-2955	187	13	weller	weller	PROPN
fnp-2955	187	14	ro	ro	PROPN
fnp-2955	187	15	,	,	PUNCT
fnp-2955	187	16	nicoll	nicoll	PROPN
fnp-2955	187	17	ja	ja	PROPN
fnp-2955	187	18	,	,	PUNCT
fnp-2955	187	19	et	et	PROPN
fnp-2955	187	20	al	al	PROPN
fnp-2955	187	21	.	.	PUNCT
fnp-2955	187	22	perivascular	perivascular	ADJ
fnp-2955	187	23	drainage	drainage	NOUN
fnp-2955	187	24	of	of	ADP
fnp-2955	187	25	solutes	solute	NOUN
fnp-2955	187	26	is	be	AUX
fnp-2955	187	27	impaired	impair	VERB
fnp-2955	187	28	in	in	ADP
fnp-2955	187	29	the	the	DET
fnp-2955	187	30	ageing	age	VERB
fnp-2955	187	31	mouse	mouse	NOUN
fnp-2955	187	32	brain	brain	NOUN
fnp-2955	187	33	and	and	CCONJ
fnp-2955	187	34	in	in	ADP
fnp-2955	187	35	the	the	DET
fnp-2955	187	36	presence	presence	NOUN
fnp-2955	187	37	of	of	ADP
fnp-2955	187	38	cerebral	cerebral	ADJ
fnp-2955	187	39	amyloid	amyloid	NOUN
fnp-2955	187	40	angiopathy	angiopathy	NOUN
fnp-2955	187	41	.	.	PUNCT
fnp-2955	188	1	acta	acta	PROPN
fnp-2955	188	2	neuropathol	neuropathol	PROPN
fnp-2955	188	3	.	.	PUNCT
fnp-2955	189	1	2011;121(4):431	2011;121(4):431	NUM
fnp-2955	189	2	-	-	SYM
fnp-2955	189	3	43	43	NUM
fnp-2955	189	4	.	.	PUNCT
fnp-2955	190	1	15	15	NUM
fnp-2955	190	2	.	.	PUNCT
fnp-2955	191	1	keable	keable	ADJ
fnp-2955	191	2	a	a	DET
fnp-2955	191	3	,	,	PUNCT
fnp-2955	191	4	fenna	fenna	NOUN
fnp-2955	191	5	k	k	NOUN
fnp-2955	191	6	,	,	PUNCT
fnp-2955	191	7	yuen	yuen	PROPN
fnp-2955	191	8	hm	hm	PROPN
fnp-2955	191	9	,	,	PUNCT
fnp-2955	191	10	johnston	johnston	PROPN
fnp-2955	191	11	da	da	PROPN
fnp-2955	191	12	,	,	PUNCT
fnp-2955	191	13	smyth	smyth	PROPN
fnp-2955	191	14	nr	nr	PROPN
fnp-2955	191	15	,	,	PUNCT
fnp-2955	191	16	smith	smith	PROPN
fnp-2955	191	17	c	c	PROPN
fnp-2955	191	18	,	,	PUNCT
fnp-2955	191	19	et	et	PROPN
fnp-2955	191	20	al	al	PROPN
fnp-2955	191	21	.	.	PUNCT
fnp-2955	191	22	deposition	deposition	NOUN
fnp-2955	191	23	of	of	ADP
fnp-2955	191	24	amyloid	amyloid	NOUN
fnp-2955	191	25	beta	beta	NOUN
fnp-2955	191	26	in	in	ADP
fnp-2955	191	27	the	the	DET
fnp-2955	191	28	walls	wall	NOUN
fnp-2955	191	29	of	of	ADP
fnp-2955	191	30	human	human	ADJ
fnp-2955	191	31	leptomeningeal	leptomeningeal	NOUN
fnp-2955	191	32	arteries	artery	NOUN
fnp-2955	191	33	in	in	ADP
fnp-2955	191	34	relation	relation	NOUN
fnp-2955	191	35	to	to	ADP
fnp-2955	191	36	perivascular	perivascular	ADJ
fnp-2955	191	37	drainage	drainage	NOUN
fnp-2955	191	38	pathways	pathway	NOUN
fnp-2955	191	39	in	in	ADP
fnp-2955	191	40	cerebral	cerebral	ADJ
fnp-2955	191	41	amyloid	amyloid	NOUN
fnp-2955	191	42	angiopathy	angiopathy	NOUN
fnp-2955	191	43	.	.	PUNCT
fnp-2955	192	1	biochimica	biochimica	PROPN
fnp-2955	192	2	et	et	PROPN
fnp-2955	192	3	biophysica	biophysica	PROPN
fnp-2955	192	4	acta	acta	PROPN
fnp-2955	192	5	.	.	PUNCT
fnp-2955	193	1	2016;1862(5):1037	2016;1862(5):1037	NUM
fnp-2955	193	2	-	-	SYM
fnp-2955	193	3	46	46	NUM
fnp-2955	193	4	.	.	PUNCT
fnp-2955	194	1	16	16	NUM
fnp-2955	194	2	.	.	PUNCT
fnp-2955	195	1	hawkes	hawkes	PROPN
fnp-2955	195	2	ca	can	AUX
fnp-2955	195	3	,	,	PUNCT
fnp-2955	195	4	gatherer	gatherer	PROPN
fnp-2955	195	5	m	m	PROPN
fnp-2955	195	6	,	,	PUNCT
fnp-2955	195	7	sharp	sharp	PROPN
fnp-2955	195	8	mm	mm	PROPN
fnp-2955	195	9	,	,	PUNCT
fnp-2955	195	10	dorr	dorr	PROPN
fnp-2955	195	11	a	a	PROPN
fnp-2955	195	12	,	,	PUNCT
fnp-2955	195	13	yuen	yuen	PROPN
fnp-2955	195	14	hm	hm	PROPN
fnp-2955	195	15	,	,	PUNCT
fnp-2955	195	16	kalaria	kalaria	PROPN
fnp-2955	195	17	r	r	PROPN
fnp-2955	195	18	,	,	PUNCT
fnp-2955	195	19	et	et	PROPN
fnp-2955	195	20	al	al	PROPN
fnp-2955	195	21	.	.	PUNCT
fnp-2955	196	1	regional	regional	ADJ
fnp-2955	196	2	differences	difference	NOUN
fnp-2955	196	3	in	in	ADP
fnp-2955	196	4	the	the	DET
fnp-2955	196	5	morphological	morphological	ADJ
fnp-2955	196	6	and	and	CCONJ
fnp-2955	196	7	functional	functional	ADJ
fnp-2955	196	8	effects	effect	NOUN
fnp-2955	196	9	of	of	ADP
fnp-2955	196	10	aging	aging	NOUN
fnp-2955	196	11	on	on	ADP
fnp-2955	196	12	cerebral	cerebral	ADJ
fnp-2955	196	13	basement	basement	NOUN
fnp-2955	196	14	membranes	membrane	NOUN
fnp-2955	196	15	and	and	CCONJ
fnp-2955	196	16	perivascular	perivascular	ADJ
fnp-2955	196	17	drainage	drainage	NOUN
fnp-2955	196	18	of	of	ADP
fnp-2955	196	19	amyloid	amyloid	NOUN
fnp-2955	196	20	-	-	PUNCT
fnp-2955	196	21	beta	beta	NOUN
fnp-2955	196	22	from	from	ADP
fnp-2955	196	23	the	the	DET
fnp-2955	196	24	mouse	mouse	NOUN
fnp-2955	196	25	brain	brain	NOUN
fnp-2955	196	26	.	.	PUNCT
fnp-2955	197	1	aging	age	VERB
fnp-2955	197	2	cell	cell	NOUN
fnp-2955	197	3	.	.	PUNCT
fnp-2955	198	1	2013;12(2):224	2013;12(2):224	NUM
fnp-2955	198	2	-	-	SYM
fnp-2955	198	3	36	36	NUM
fnp-2955	198	4	.	.	PUNCT
fnp-2955	198	5	17	17	NUM
fnp-2955	198	6	.	.	PUNCT
fnp-2955	199	1	manousopoulou	manousopoulou	PROPN
fnp-2955	199	2	a	a	PRON
fnp-2955	199	3	,	,	PUNCT
fnp-2955	199	4	gatherer	gatherer	PROPN
fnp-2955	199	5	m	m	PROPN
fnp-2955	199	6	,	,	PUNCT
fnp-2955	199	7	smith	smith	PROPN
fnp-2955	199	8	c	c	PROPN
fnp-2955	199	9	,	,	PUNCT
fnp-2955	199	10	nicoll	nicoll	PROPN
fnp-2955	199	11	ja	ja	PROPN
fnp-2955	199	12	,	,	PUNCT
fnp-2955	199	13	woelk	woelk	PROPN
fnp-2955	199	14	ch	ch	PROPN
fnp-2955	199	15	,	,	PUNCT
fnp-2955	199	16	johnson	johnson	PROPN
fnp-2955	199	17	m	m	PROPN
fnp-2955	199	18	,	,	PUNCT
fnp-2955	199	19	et	et	PROPN
fnp-2955	199	20	al	al	PROPN
fnp-2955	199	21	.	.	PUNCT
fnp-2955	200	1	systems	system	NOUN
fnp-2955	200	2	proteomic	proteomic	ADJ
fnp-2955	200	3	analysis	analysis	NOUN
fnp-2955	200	4	reveals	reveal	VERB
fnp-2955	200	5	that	that	SCONJ
fnp-2955	200	6	clusterin	clusterin	NOUN
fnp-2955	200	7	and	and	CCONJ
fnp-2955	200	8	tissue	tissue	NOUN
fnp-2955	200	9	inhibitor	inhibitor	NOUN
fnp-2955	200	10	of	of	ADP
fnp-2955	200	11	metalloproteinases	metalloproteinase	NOUN
fnp-2955	200	12	3	3	NUM
fnp-2955	200	13	increase	increase	NOUN
fnp-2955	200	14	in	in	ADP
fnp-2955	200	15	leptomeningeal	leptomeningeal	ADJ
fnp-2955	200	16	arteries	artery	NOUN
fnp-2955	200	17	affected	affect	VERB
fnp-2955	200	18	by	by	ADP
fnp-2955	200	19	cerebral	cerebral	ADJ
fnp-2955	200	20	amyloid	amyloid	NOUN
fnp-2955	200	21	angiopathy	angiopathy	NOUN
fnp-2955	200	22	.	.	PUNCT
fnp-2955	201	1	neuropathol	neuropathol	PROPN
fnp-2955	201	2	appl	appl	PROPN
fnp-2955	201	3	neurobiol	neurobiol	PROPN
fnp-2955	201	4	.	.	PUNCT
fnp-2955	202	1	2017	2017	NUM
fnp-2955	202	2	oct;43(6):492	oct;43(6):492	NOUN
fnp-2955	202	3	-	-	PUNCT
fnp-2955	202	4	504	504	NUM
fnp-2955	202	5	.	.	PUNCT
fnp-2955	202	6	18	18	NUM
fnp-2955	202	7	.	.	PUNCT
fnp-2955	203	1	braak	braak	PROPN
fnp-2955	203	2	h	h	PROPN
fnp-2955	203	3	,	,	PUNCT
fnp-2955	203	4	braak	braak	PROPN
fnp-2955	203	5	e.	e.	PROPN
fnp-2955	203	6	neuropathological	neuropathological	PROPN
fnp-2955	203	7	stageing	stage	VERB
fnp-2955	203	8	of	of	ADP
fnp-2955	203	9	alzheimer	alzheimer	NOUN
fnp-2955	203	10	-	-	PUNCT
fnp-2955	203	11	related	relate	VERB
fnp-2955	203	12	changes	change	NOUN
fnp-2955	203	13	.	.	PUNCT
fnp-2955	204	1	acta	acta	PROPN
fnp-2955	204	2	neuropathol	neuropathol	PROPN
fnp-2955	204	3	.	.	PUNCT
fnp-2955	205	1	1991;82:239	1991;82:239	NUM
fnp-2955	205	2	-	-	SYM
fnp-2955	205	3	59	59	NUM
fnp-2955	205	4	.	.	NOUN
fnp-2955	206	1	19	19	NUM
fnp-2955	206	2	.	.	PUNCT
fnp-2955	206	3	thal	thal	PROPN
fnp-2955	206	4	dr	dr	PROPN
fnp-2955	206	5	,	,	PUNCT
fnp-2955	206	6	rub	rub	NOUN
fnp-2955	206	7	u	u	NOUN
fnp-2955	206	8	,	,	PUNCT
fnp-2955	206	9	schultz	schultz	PROPN
fnp-2955	206	10	c	c	PROPN
fnp-2955	206	11	,	,	PUNCT
fnp-2955	206	12	sassin	sassin	VERB
fnp-2955	206	13	i	i	PRON
fnp-2955	206	14	,	,	PUNCT
fnp-2955	206	15	ghebremedhin	ghebremedhin	NOUN
fnp-2955	206	16	e	e	PROPN
fnp-2955	206	17	,	,	PUNCT
fnp-2955	206	18	del	del	PROPN
fnp-2955	206	19	tredici	tredici	PROPN
fnp-2955	206	20	k	k	PROPN
fnp-2955	206	21	,	,	PUNCT
fnp-2955	206	22	et	et	PROPN
fnp-2955	206	23	al	al	PROPN
fnp-2955	206	24	.	.	PROPN
fnp-2955	206	25	sequence	sequence	NOUN
fnp-2955	206	26	of	of	ADP
fnp-2955	206	27	abeta	abeta	ADJ
fnp-2955	206	28	-	-	PUNCT
fnp-2955	206	29	protein	protein	NOUN
fnp-2955	206	30	deposition	deposition	NOUN
fnp-2955	206	31	in	in	ADP
fnp-2955	206	32	the	the	DET
fnp-2955	206	33	human	human	ADJ
fnp-2955	206	34	medial	medial	ADJ
fnp-2955	206	35	temporal	temporal	ADJ
fnp-2955	206	36	lobe	lobe	NOUN
fnp-2955	206	37	.	.	PUNCT
fnp-2955	207	1	journal	journal	NOUN
fnp-2955	207	2	of	of	ADP
fnp-2955	207	3	neuropathology	neuropathology	NOUN
fnp-2955	207	4	and	and	CCONJ
fnp-2955	207	5	experimental	experimental	ADJ
fnp-2955	207	6	neurology	neurology	NOUN
fnp-2955	207	7	.	.	PUNCT
fnp-2955	208	1	2000;59(8):733	2000;59(8):733	NUM
fnp-2955	208	2	-	-	SYM
fnp-2955	208	3	48	48	NUM
fnp-2955	208	4	.	.	PUNCT
fnp-2955	208	5	20	20	NUM
fnp-2955	208	6	.	.	PUNCT
fnp-2955	209	1	morris	morris	PROPN
fnp-2955	209	2	jc	jc	PROPN
fnp-2955	209	3	,	,	PUNCT
fnp-2955	209	4	mohs	mohs	PROPN
fnp-2955	209	5	rc	rc	PROPN
fnp-2955	209	6	,	,	PUNCT
fnp-2955	209	7	rogers	rogers	PROPN
fnp-2955	209	8	h	h	PROPN
fnp-2955	209	9	,	,	PUNCT
fnp-2955	209	10	fillenbaum	fillenbaum	NOUN
fnp-2955	209	11	g	g	PROPN
fnp-2955	209	12	,	,	PUNCT
fnp-2955	209	13	heyman	heyman	PROPN
fnp-2955	209	14	a.	a.	PROPN
fnp-2955	209	15	consortium	consortium	PROPN
fnp-2955	209	16	to	to	PART
fnp-2955	209	17	establish	establish	VERB
fnp-2955	209	18	a	a	DET
fnp-2955	209	19	registry	registry	NOUN
fnp-2955	209	20	for	for	ADP
fnp-2955	209	21	alzheimer	alzheimer	PROPN
fnp-2955	209	22	's	's	PART
fnp-2955	209	23	disease	disease	NOUN
fnp-2955	209	24	(	(	PUNCT
fnp-2955	209	25	cerad	cerad	NOUN
fnp-2955	209	26	)	)	PUNCT
fnp-2955	209	27	clinical	clinical	ADJ
fnp-2955	209	28	and	and	CCONJ
fnp-2955	209	29	neuropsychological	neuropsychological	ADJ
fnp-2955	209	30	assessment	assessment	NOUN
fnp-2955	209	31	of	of	ADP
fnp-2955	209	32	alzheimer	alzheimer	PROPN
fnp-2955	209	33	's	's	PART
fnp-2955	209	34	disease	disease	NOUN
fnp-2955	209	35	.	.	PUNCT
fnp-2955	210	1	psychopharmacol	psychopharmacol	PROPN
fnp-2955	210	2	bull	bull	NOUN
fnp-2955	210	3	.	.	PUNCT
fnp-2955	211	1	1988;24(4):641	1988;24(4):641	NUM
fnp-2955	211	2	-	-	SYM
fnp-2955	211	3	52	52	NUM
fnp-2955	211	4	.	.	PUNCT
fnp-2955	212	1	21	21	NUM
fnp-2955	212	2	.	.	PUNCT
fnp-2955	213	1	gomes	gomes	PROPN
fnp-2955	213	2	lc	lc	PROPN
fnp-2955	213	3	,	,	PUNCT
fnp-2955	213	4	scorrano	scorrano	PROPN
fnp-2955	213	5	l.	l.	PROPN
fnp-2955	213	6	high	high	PROPN
fnp-2955	213	7	levels	level	NOUN
fnp-2955	213	8	of	of	ADP
fnp-2955	213	9	fis1	fis1	PROPN
fnp-2955	213	10	,	,	PUNCT
fnp-2955	213	11	a	a	DET
fnp-2955	213	12	pro	pro	ADJ
fnp-2955	213	13	-	-	ADJ
fnp-2955	213	14	fission	fission	ADJ
fnp-2955	213	15	mitochondrial	mitochondrial	ADJ
fnp-2955	213	16	protein	protein	NOUN
fnp-2955	213	17	,	,	PUNCT
fnp-2955	213	18	trigger	trigger	NOUN
fnp-2955	213	19	autophagy	autophagy	NOUN
fnp-2955	213	20	.	.	PUNCT
fnp-2955	214	1	biochimica	biochimica	PROPN
fnp-2955	214	2	et	et	PROPN
fnp-2955	214	3	biophysica	biophysica	PROPN
fnp-2955	214	4	acta	acta	PROPN
fnp-2955	214	5	.	.	PUNCT
fnp-2955	215	1	2008;1777(7	2008;1777(7	X
fnp-2955	215	2	-	-	PUNCT
fnp-2955	215	3	8):860	8):860	NUM
fnp-2955	215	4	-	-	SYM
fnp-2955	215	5	6	6	NUM
fnp-2955	215	6	.	.	NOUN
fnp-2955	215	7	22	22	NUM
fnp-2955	215	8	.	.	PUNCT
fnp-2955	216	1	castano	castano	PROPN
fnp-2955	216	2	em	em	PRON
fnp-2955	216	3	,	,	PUNCT
fnp-2955	216	4	maarouf	maarouf	CCONJ
fnp-2955	216	5	cl	cl	PROPN
fnp-2955	216	6	,	,	PUNCT
fnp-2955	216	7	wu	wu	PROPN
fnp-2955	216	8	t	t	PROPN
fnp-2955	216	9	,	,	PUNCT
fnp-2955	216	10	leal	leal	PROPN
fnp-2955	216	11	mc	mc	PROPN
fnp-2955	216	12	,	,	PUNCT
fnp-2955	216	13	whiteside	whiteside	PROPN
fnp-2955	216	14	cm	cm	PROPN
fnp-2955	216	15	,	,	PUNCT
fnp-2955	216	16	lue	lue	PROPN
fnp-2955	216	17	lf	lf	PROPN
fnp-2955	216	18	,	,	PUNCT
fnp-2955	216	19	et	et	PROPN
fnp-2955	216	20	al	al	PROPN
fnp-2955	216	21	.	.	PROPN
fnp-2955	216	22	alzheimer	alzheimer	PROPN
fnp-2955	216	23	disease	disease	PROPN
fnp-2955	216	24	periventricular	periventricular	ADJ
fnp-2955	216	25	white	white	ADJ
fnp-2955	216	26	matter	matter	NOUN
fnp-2955	216	27	lesions	lesion	NOUN
fnp-2955	216	28	exhibit	exhibit	VERB
fnp-2955	216	29	specific	specific	ADJ
fnp-2955	216	30	proteomic	proteomic	ADJ
fnp-2955	216	31	profile	profile	NOUN
fnp-2955	216	32	alterations	alteration	NOUN
fnp-2955	216	33	.	.	PUNCT
fnp-2955	217	1	neurochemistry	neurochemistry	PROPN
fnp-2955	217	2	international	international	PROPN
fnp-2955	217	3	.	.	PUNCT
fnp-2955	218	1	2013;62(2):145	2013;62(2):145	NUM
fnp-2955	218	2	-	-	SYM
fnp-2955	218	3	56	56	NUM
fnp-2955	218	4	.	.	NOUN
fnp-2955	218	5	23	23	NUM
fnp-2955	218	6	.	.	PUNCT
fnp-2955	219	1	baek	baek	PROPN
fnp-2955	219	2	jh	jh	PROPN
fnp-2955	219	3	,	,	PUNCT
fnp-2955	219	4	liu	liu	PROPN
fnp-2955	219	5	yv	yv	PROPN
fnp-2955	219	6	,	,	PUNCT
fnp-2955	219	7	mcdonald	mcdonald	PROPN
fnp-2955	219	8	kr	kr	PROPN
fnp-2955	219	9	,	,	PUNCT
fnp-2955	219	10	wesley	wesley	PROPN
fnp-2955	219	11	jb	jb	PROPN
fnp-2955	219	12	,	,	PUNCT
fnp-2955	219	13	hubbi	hubbi	VERB
fnp-2955	219	14	me	i	PRON
fnp-2955	219	15	,	,	PUNCT
fnp-2955	219	16	byun	byun	NOUN
fnp-2955	219	17	h	h	PROPN
fnp-2955	219	18	,	,	PUNCT
fnp-2955	219	19	et	et	PROPN
fnp-2955	219	20	al	al	PROPN
fnp-2955	219	21	.	.	PROPN
fnp-2955	219	22	spermidine	spermidine	PROPN
fnp-2955	219	23	/	/	SYM
fnp-2955	219	24	spermine	spermine	NOUN
fnp-2955	219	25	-	-	PUNCT
fnp-2955	219	26	n1	n1	NOUN
fnp-2955	219	27	-	-	PUNCT
fnp-2955	219	28	acetyltransferase	acetyltransferase	NOUN
fnp-2955	219	29	2	2	NUM
fnp-2955	219	30	is	be	AUX
fnp-2955	219	31	an	an	DET
fnp-2955	219	32	essential	essential	ADJ
fnp-2955	219	33	component	component	NOUN
fnp-2955	219	34	of	of	ADP
fnp-2955	219	35	the	the	DET
fnp-2955	219	36	ubiquitin	ubiquitin	ADJ
fnp-2955	219	37	ligase	ligase	PROPN
fnp-2955	219	38	complex	complex	NOUN
fnp-2955	219	39	that	that	PRON
fnp-2955	219	40	regulates	regulate	VERB
fnp-2955	219	41	hypoxia	hypoxia	NOUN
fnp-2955	219	42	-	-	PUNCT
fnp-2955	219	43	inducible	inducible	ADJ
fnp-2955	219	44	factor	factor	NOUN
fnp-2955	219	45	1alpha	1alpha	NUM
fnp-2955	219	46	.	.	PUNCT
fnp-2955	220	1	j	j	PROPN
fnp-2955	220	2	biol	biol	PROPN
fnp-2955	220	3	chem	chem	NOUN
fnp-2955	220	4	.	.	PUNCT
fnp-2955	221	1	2007;282(32):23572	2007;282(32):23572	X
fnp-2955	221	2	-	-	SYM
fnp-2955	221	3	80	80	NUM
fnp-2955	221	4	.	.	PUNCT
fnp-2955	222	1	24	24	NUM
fnp-2955	222	2	.	.	PUNCT
fnp-2955	223	1	liu	liu	PROPN
fnp-2955	223	2	yv	yv	PROPN
fnp-2955	223	3	,	,	PUNCT
fnp-2955	223	4	semenza	semenza	PROPN
fnp-2955	223	5	gl	gl	PROPN
fnp-2955	223	6	.	.	PROPN
fnp-2955	223	7	rack1	rack1	PROPN
fnp-2955	223	8	vs.	vs.	ADP
fnp-2955	223	9	hsp90	hsp90	NOUN
fnp-2955	223	10	:	:	PUNCT
fnp-2955	223	11	competition	competition	NOUN
fnp-2955	223	12	for	for	ADP
fnp-2955	223	13	hif-1	hif-1	PUNCT
fnp-2955	223	14	alpha	alpha	NOUN
fnp-2955	223	15	degradation	degradation	NOUN
fnp-2955	223	16	vs.	vs.	ADP
fnp-2955	223	17	stabilization	stabilization	NOUN
fnp-2955	223	18	.	.	PUNCT
fnp-2955	224	1	cell	cell	NOUN
fnp-2955	224	2	cycle	cycle	NOUN
fnp-2955	224	3	.	.	PUNCT
fnp-2955	225	1	2007;6(6):656	2007;6(6):656	NUM
fnp-2955	225	2	-	-	SYM
fnp-2955	225	3	9	9	NUM
fnp-2955	225	4	.	.	NUM
fnp-2955	225	5	25	25	NUM
fnp-2955	225	6	.	.	PUNCT
fnp-2955	226	1	khoshnoodi	khoshnoodi	PROPN
fnp-2955	226	2	j	j	PROPN
fnp-2955	226	3	,	,	PUNCT
fnp-2955	226	4	pedchenko	pedchenko	PROPN
fnp-2955	226	5	v	v	NOUN
fnp-2955	226	6	,	,	PUNCT
fnp-2955	226	7	hudson	hudson	PROPN
fnp-2955	226	8	bg	bg	PROPN
fnp-2955	226	9	.	.	PUNCT
fnp-2955	227	1	mammalian	mammalian	PROPN
fnp-2955	227	2	collagen	collagen	PROPN
fnp-2955	227	3	iv	iv	X
fnp-2955	227	4	.	.	PUNCT
fnp-2955	227	5	microsc	microsc	PROPN
fnp-2955	227	6	res	re	NOUN
fnp-2955	227	7	tech	tech	NOUN
fnp-2955	227	8	.	.	PUNCT
fnp-2955	228	1	2008;71(5):357	2008;71(5):357	NUM
fnp-2955	228	2	-	-	PUNCT
fnp-2955	228	3	70	70	NUM
fnp-2955	228	4	.	.	PUNCT
fnp-2955	229	1	26	26	NUM
fnp-2955	229	2	.	.	PUNCT
fnp-2955	229	3	rannikmae	rannikmae	PROPN
fnp-2955	229	4	k	k	PROPN
fnp-2955	229	5	,	,	PUNCT
fnp-2955	229	6	davies	davy	NOUN
fnp-2955	229	7	g	g	PROPN
fnp-2955	229	8	,	,	PUNCT
fnp-2955	229	9	thomson	thomson	PROPN
fnp-2955	229	10	pa	pa	PROPN
fnp-2955	229	11	,	,	PUNCT
fnp-2955	229	12	bevan	bevan	PROPN
fnp-2955	229	13	s	s	PROPN
fnp-2955	229	14	,	,	PUNCT
fnp-2955	229	15	devan	devan	PROPN
fnp-2955	229	16	wj	wj	PROPN
fnp-2955	229	17	,	,	PUNCT
fnp-2955	229	18	falcone	falcone	PROPN
fnp-2955	229	19	gj	gj	PROPN
fnp-2955	229	20	,	,	PUNCT
fnp-2955	229	21	et	et	PROPN
fnp-2955	229	22	al	al	PROPN
fnp-2955	229	23	.	.	PROPN
fnp-2955	230	1	common	common	ADJ
fnp-2955	230	2	variation	variation	NOUN
fnp-2955	230	3	in	in	ADP
fnp-2955	230	4	col4a1	col4a1	PROPN
fnp-2955	230	5	/	/	SYM
fnp-2955	230	6	col4a2	col4a2	PROPN
fnp-2955	230	7	is	be	AUX
fnp-2955	230	8	associated	associate	VERB
fnp-2955	230	9	with	with	ADP
fnp-2955	230	10	sporadic	sporadic	ADJ
fnp-2955	230	11	cerebral	cerebral	ADJ
fnp-2955	230	12	small	small	ADJ
fnp-2955	230	13	vessel	vessel	NOUN
fnp-2955	230	14	disease	disease	NOUN
fnp-2955	230	15	.	.	PUNCT
fnp-2955	231	1	neurology	neurology	NOUN
fnp-2955	231	2	.	.	PUNCT
fnp-2955	232	1	2015;84(9):918	2015;84(9):918	NUM
fnp-2955	232	2	-	-	SYM
fnp-2955	232	3	26	26	NUM
fnp-2955	232	4	.	.	PUNCT
fnp-2955	233	1	27	27	NUM
fnp-2955	233	2	.	.	PUNCT
fnp-2955	234	1	kalaria	kalaria	PROPN
fnp-2955	234	2	rn	rn	PROPN
fnp-2955	234	3	,	,	PUNCT
fnp-2955	234	4	pax	pax	PROPN
fnp-2955	234	5	ab	ab	PROPN
fnp-2955	234	6	.	.	PROPN
fnp-2955	234	7	increased	increase	VERB
fnp-2955	234	8	collagen	collagen	NOUN
fnp-2955	234	9	content	content	NOUN
fnp-2955	234	10	of	of	ADP
fnp-2955	234	11	cerebral	cerebral	ADJ
fnp-2955	234	12	microvessels	microvessel	NOUN
fnp-2955	234	13	in	in	ADP
fnp-2955	234	14	alzheimer	alzheimer	PROPN
fnp-2955	234	15	's	's	PART
fnp-2955	234	16	disease	disease	NOUN
fnp-2955	234	17	.	.	PUNCT
fnp-2955	235	1	brain	brain	NOUN
fnp-2955	235	2	research	research	NOUN
fnp-2955	235	3	.	.	PUNCT
fnp-2955	236	1	1995;705(1	1995;705(1	X
fnp-2955	236	2	-	-	PUNCT
fnp-2955	236	3	2):349	2):349	PROPN
fnp-2955	236	4	-	-	PUNCT
fnp-2955	236	5	52	52	NUM
fnp-2955	236	6	.	.	PUNCT
fnp-2955	237	1	28	28	NUM
fnp-2955	237	2	.	.	PUNCT
fnp-2955	238	1	snorradottir	snorradottir	PROPN
fnp-2955	238	2	ao	ao	PROPN
fnp-2955	238	3	,	,	PUNCT
fnp-2955	238	4	isaksson	isaksson	PROPN
fnp-2955	238	5	hj	hj	PROPN
fnp-2955	238	6	,	,	PUNCT
fnp-2955	238	7	kaeser	kaeser	PROPN
fnp-2955	238	8	sa	sa	PROPN
fnp-2955	238	9	,	,	PUNCT
fnp-2955	238	10	skodras	skodras	PROPN
fnp-2955	238	11	aa	aa	PROPN
fnp-2955	238	12	,	,	PUNCT
fnp-2955	238	13	olafsson	olafsson	NOUN
fnp-2955	238	14	e	e	PROPN
fnp-2955	238	15	,	,	PUNCT
fnp-2955	238	16	palsdottir	palsdottir	PROPN
fnp-2955	238	17	a	a	PRON
fnp-2955	238	18	,	,	PUNCT
fnp-2955	238	19	et	et	PROPN
fnp-2955	238	20	al	al	PROPN
fnp-2955	238	21	.	.	PUNCT
fnp-2955	238	22	deposition	deposition	NOUN
fnp-2955	238	23	of	of	ADP
fnp-2955	238	24	collagen	collagen	NOUN
fnp-2955	238	25	iv	iv	X
fnp-2955	238	26	and	and	CCONJ
fnp-2955	238	27	aggrecan	aggrecan	ADJ
fnp-2955	238	28	in	in	ADP
fnp-2955	238	29	leptomeningeal	leptomeningeal	ADJ
fnp-2955	238	30	arteries	artery	NOUN
fnp-2955	238	31	of	of	ADP
fnp-2955	238	32	hereditary	hereditary	ADJ
fnp-2955	238	33	brain	brain	NOUN
fnp-2955	238	34	haemorrhage	haemorrhage	NOUN
fnp-2955	238	35	with	with	ADP
fnp-2955	238	36	amyloidosis	amyloidosis	NOUN
fnp-2955	238	37	.	.	PUNCT
fnp-2955	239	1	brain	brain	NOUN
fnp-2955	239	2	research	research	NOUN
fnp-2955	239	3	.	.	PUNCT
fnp-2955	240	1	2013;1535:106	2013;1535:106	X
fnp-2955	240	2	-	-	SYM
fnp-2955	240	3	14	14	NUM
fnp-2955	240	4	.	.	PUNCT
fnp-2955	241	1	29	29	NUM
fnp-2955	241	2	.	.	PUNCT
fnp-2955	242	1	hondius	hondius	PROPN
fnp-2955	242	2	dc	dc	PROPN
fnp-2955	242	3	,	,	PUNCT
fnp-2955	242	4	eigenhuis	eigenhuis	PROPN
fnp-2955	242	5	kn	kn	PROPN
fnp-2955	242	6	,	,	PUNCT
fnp-2955	242	7	morrema	morrema	PROPN
fnp-2955	242	8	thj	thj	PROPN
fnp-2955	242	9	,	,	PUNCT
fnp-2955	242	10	van	van	PROPN
fnp-2955	242	11	der	der	PROPN
fnp-2955	242	12	schors	schors	PROPN
fnp-2955	242	13	rc	rc	PROPN
fnp-2955	242	14	,	,	PUNCT
fnp-2955	242	15	van	van	PROPN
fnp-2955	242	16	nierop	nierop	PROPN
fnp-2955	242	17	p	p	X
fnp-2955	242	18	,	,	PUNCT
fnp-2955	242	19	bugiani	bugiani	PROPN
fnp-2955	242	20	m	m	PROPN
fnp-2955	242	21	,	,	PUNCT
fnp-2955	242	22	et	et	PROPN
fnp-2955	242	23	al	al	PROPN
fnp-2955	242	24	.	.	PUNCT
fnp-2955	243	1	proteomics	proteomic	NOUN
fnp-2955	243	2	analysis	analysis	NOUN
fnp-2955	243	3	identifies	identify	VERB
fnp-2955	243	4	new	new	ADJ
fnp-2955	243	5	markers	marker	NOUN
fnp-2955	243	6	associated	associate	VERB
fnp-2955	243	7	with	with	ADP
fnp-2955	243	8	capillary	capillary	ADJ
fnp-2955	243	9	cerebral	cerebral	ADJ
fnp-2955	243	10	amyloid	amyloid	NOUN
fnp-2955	243	11	angiopathy	angiopathy	NOUN
fnp-2955	243	12	in	in	ADP
fnp-2955	243	13	alzheimer	alzheimer	PROPN
fnp-2955	243	14	's	's	PART
fnp-2955	243	15	disease	disease	NOUN
fnp-2955	243	16	.	.	PUNCT
fnp-2955	244	1	acta	acta	PROPN
fnp-2955	244	2	neuropathol	neuropathol	PROPN
fnp-2955	244	3	commun	commun	PROPN
fnp-2955	244	4	.	.	PUNCT
fnp-2955	245	1	2018;6(1):46	2018;6(1):46	NUM
fnp-2955	245	2	.	.	X
fnp-2955	245	3	30	30	NUM
fnp-2955	245	4	.	.	PUNCT
fnp-2955	245	5	trout	trout	PROPN
fnp-2955	245	6	al	al	PROPN
fnp-2955	245	7	,	,	PUNCT
fnp-2955	245	8	rutkai	rutkai	PROPN
fnp-2955	245	9	i	i	PRON
fnp-2955	245	10	,	,	PUNCT
fnp-2955	245	11	biose	biose	ADJ
fnp-2955	245	12	ij	ij	NOUN
fnp-2955	245	13	,	,	PUNCT
fnp-2955	245	14	bix	bix	PROPN
fnp-2955	245	15	gj	gj	PROPN
fnp-2955	245	16	.	.	PUNCT
fnp-2955	246	1	review	review	PROPN
fnp-2955	246	2	of	of	ADP
fnp-2955	246	3	alterations	alteration	NOUN
fnp-2955	246	4	in	in	ADP
fnp-2955	246	5	perlecan	perlecan	NOUN
fnp-2955	246	6	-	-	PUNCT
fnp-2955	246	7	associated	associate	VERB
fnp-2955	246	8	vascular	vascular	ADJ
fnp-2955	246	9	risk	risk	NOUN
fnp-2955	246	10	factors	factor	NOUN
fnp-2955	246	11	in	in	ADP
fnp-2955	246	12	dementia	dementia	NOUN
fnp-2955	246	13	.	.	PUNCT
fnp-2955	247	1	int	int	PROPN
fnp-2955	247	2	j	j	PROPN
fnp-2955	247	3	mol	mol	ADP
fnp-2955	247	4	sci	sci	PROPN
fnp-2955	247	5	.	.	PROPN
fnp-2955	247	6	2020;21(2	2020;21(2	NUM
fnp-2955	247	7	)	)	PUNCT
fnp-2955	247	8	.	.	PUNCT
fnp-2955	248	1	31	31	NUM
fnp-2955	248	2	.	.	PUNCT
fnp-2955	249	1	castillo	castillo	PROPN
fnp-2955	249	2	gm	gm	PROPN
fnp-2955	249	3	,	,	PUNCT
fnp-2955	249	4	ngo	ngo	PROPN
fnp-2955	249	5	c	c	AUX
fnp-2955	249	6	,	,	PUNCT
fnp-2955	249	7	cummings	cummings	PROPN
fnp-2955	249	8	j	j	PROPN
fnp-2955	249	9	,	,	PUNCT
fnp-2955	249	10	wight	wight	PROPN
fnp-2955	249	11	tn	tn	PROPN
fnp-2955	249	12	,	,	PUNCT
fnp-2955	249	13	snow	snow	NOUN
fnp-2955	249	14	ad	ad	NOUN
fnp-2955	249	15	.	.	PUNCT
fnp-2955	250	1	perlecan	perlecan	PROPN
fnp-2955	250	2	binds	bind	VERB
fnp-2955	250	3	to	to	ADP
fnp-2955	250	4	the	the	DET
fnp-2955	250	5	beta	beta	NOUN
fnp-2955	250	6	-	-	PUNCT
fnp-2955	250	7	amyloid	amyloid	NOUN
fnp-2955	250	8	proteins	protein	NOUN
fnp-2955	250	9	(	(	PUNCT
fnp-2955	250	10	a	a	DET
fnp-2955	250	11	beta	beta	NOUN
fnp-2955	250	12	)	)	PUNCT
fnp-2955	250	13	of	of	ADP
fnp-2955	250	14	alzheimer	alzheimer	PROPN
fnp-2955	250	15	's	's	PART
fnp-2955	250	16	disease	disease	NOUN
fnp-2955	250	17	,	,	PUNCT
fnp-2955	250	18	accelerates	accelerate	VERB
fnp-2955	250	19	a	a	DET
fnp-2955	250	20	beta	beta	ADJ
fnp-2955	250	21	fibril	fibril	ADJ
fnp-2955	250	22	formation	formation	NOUN
fnp-2955	250	23	,	,	PUNCT
fnp-2955	250	24	and	and	CCONJ
fnp-2955	250	25	maintains	maintain	VERB
fnp-2955	250	26	a	a	DET
fnp-2955	250	27	beta	beta	ADJ
fnp-2955	250	28	fibril	fibril	ADJ
fnp-2955	250	29	stability	stability	NOUN
fnp-2955	250	30	.	.	PUNCT
fnp-2955	251	1	j	j	PROPN
fnp-2955	251	2	neurochem	neurochem	PROPN
fnp-2955	251	3	.	.	PUNCT
fnp-2955	252	1	1997;69(6):2452	1997;69(6):2452	NUM
fnp-2955	252	2	-	-	SYM
fnp-2955	252	3	65	65	NUM
fnp-2955	252	4	.	.	PUNCT
fnp-2955	252	5	32	32	NUM
fnp-2955	252	6	.	.	PUNCT
fnp-2955	253	1	lepelletier	lepelletier	PROPN
fnp-2955	253	2	fx	fx	PROPN
fnp-2955	253	3	,	,	PUNCT
fnp-2955	253	4	mann	mann	PROPN
fnp-2955	253	5	dm	dm	PROPN
fnp-2955	253	6	,	,	PUNCT
fnp-2955	253	7	robinson	robinson	PROPN
fnp-2955	253	8	ac	ac	PROPN
fnp-2955	253	9	,	,	PUNCT
fnp-2955	253	10	pinteaux	pinteaux	ADJ
fnp-2955	253	11	e	e	NOUN
fnp-2955	253	12	,	,	PUNCT
fnp-2955	253	13	boutin	boutin	PROPN
fnp-2955	253	14	h.	h.	PROPN
fnp-2955	253	15	early	early	ADJ
fnp-2955	253	16	changes	change	NOUN
fnp-2955	253	17	in	in	ADP
fnp-2955	253	18	extracellular	extracellular	ADJ
fnp-2955	253	19	matrix	matrix	NOUN
fnp-2955	253	20	in	in	ADP
fnp-2955	253	21	alzheimer	alzheimer	PROPN
fnp-2955	253	22	's	's	PART
fnp-2955	253	23	disease	disease	NOUN
fnp-2955	253	24	.	.	PUNCT
fnp-2955	254	1	neuropathol	neuropathol	PROPN
fnp-2955	254	2	appl	appl	PROPN
fnp-2955	254	3	neurobiol	neurobiol	PROPN
fnp-2955	254	4	.	.	PUNCT
fnp-2955	255	1	2017;43(2):167	2017;43(2):167	NUM
fnp-2955	255	2	-	-	SYM
fnp-2955	255	3	82	82	NUM
fnp-2955	255	4	.	.	PUNCT
fnp-2955	256	1	33	33	NUM
fnp-2955	256	2	.	.	PUNCT
fnp-2955	257	1	iivonen	iivonen	PROPN
fnp-2955	257	2	s	s	PROPN
fnp-2955	257	3	,	,	PUNCT
fnp-2955	257	4	helisalmi	helisalmi	PROPN
fnp-2955	257	5	s	s	PROPN
fnp-2955	257	6	,	,	PUNCT
fnp-2955	257	7	mannermaa	mannermaa	VERB
fnp-2955	257	8	a	a	DET
fnp-2955	257	9	,	,	PUNCT
fnp-2955	257	10	alafuzoff	alafuzoff	NOUN
fnp-2955	258	1	i	i	PROPN
fnp-2955	258	2	,	,	PUNCT
fnp-2955	258	3	lehtovirta	lehtovirta	PROPN
fnp-2955	258	4	m	m	PROPN
fnp-2955	258	5	,	,	PUNCT
fnp-2955	258	6	soininen	soininen	PROPN
fnp-2955	258	7	h	h	NOUN
fnp-2955	258	8	,	,	PUNCT
fnp-2955	258	9	et	et	PROPN
fnp-2955	258	10	al	al	PROPN
fnp-2955	258	11	.	.	PUNCT
fnp-2955	259	1	heparan	heparan	ADJ
fnp-2955	259	2	sulfate	sulfate	NOUN
fnp-2955	259	3	proteoglycan	proteoglycan	ADJ
fnp-2955	259	4	2	2	NUM
fnp-2955	259	5	polymorphism	polymorphism	NOUN
fnp-2955	259	6	in	in	ADP
fnp-2955	259	7	alzheimer	alzheimer	PROPN
fnp-2955	259	8	's	's	PART
fnp-2955	259	9	disease	disease	NOUN
fnp-2955	259	10	and	and	CCONJ
fnp-2955	259	11	correlation	correlation	NOUN
fnp-2955	259	12	with	with	ADP
fnp-2955	259	13	neuropathology	neuropathology	NOUN
fnp-2955	259	14	.	.	PUNCT
fnp-2955	260	1	neurosci	neurosci	PROPN
fnp-2955	260	2	lett	lett	PROPN
fnp-2955	260	3	.	.	PUNCT
fnp-2955	261	1	2003;352(2):146	2003;352(2):146	X
fnp-2955	261	2	-	-	SYM
fnp-2955	261	3	50	50	NUM
fnp-2955	261	4	.	.	PUNCT
fnp-2955	262	1	34	34	NUM
fnp-2955	262	2	.	.	PUNCT
fnp-2955	263	1	colombatti	colombatti	PROPN
fnp-2955	263	2	a	a	PRON
fnp-2955	263	3	,	,	PUNCT
fnp-2955	263	4	spessotto	spessotto	PROPN
fnp-2955	263	5	p	p	NOUN
fnp-2955	263	6	,	,	PUNCT
fnp-2955	263	7	doliana	doliana	PROPN
fnp-2955	263	8	r	r	NOUN
fnp-2955	263	9	,	,	PUNCT
fnp-2955	263	10	mongiat	mongiat	PROPN
fnp-2955	263	11	m	m	PROPN
fnp-2955	263	12	,	,	PUNCT
fnp-2955	263	13	bressan	bressan	PROPN
fnp-2955	263	14	gm	gm	PROPN
fnp-2955	263	15	,	,	PUNCT
fnp-2955	263	16	esposito	esposito	PROPN
fnp-2955	263	17	g.	g.	PROPN
fnp-2955	263	18	the	the	DET
fnp-2955	263	19	emilin	emilin	PROPN
fnp-2955	263	20	/	/	SYM
fnp-2955	263	21	multimerin	multimerin	PROPN
fnp-2955	263	22	family	family	NOUN
fnp-2955	263	23	.	.	PUNCT
fnp-2955	264	1	front	front	ADJ
fnp-2955	264	2	immunol	immunol	NOUN
fnp-2955	264	3	.	.	PUNCT
fnp-2955	265	1	2012;2:93	2012;2:93	NOUN
fnp-2955	265	2	.	.	PUNCT
fnp-2955	266	1	35	35	NUM
fnp-2955	266	2	.	.	PUNCT
fnp-2955	266	3	paulitti	paulitti	PROPN
fnp-2955	266	4	a	a	PRON
fnp-2955	266	5	,	,	PUNCT
fnp-2955	266	6	andreuzzi	andreuzzi	PROPN
fnp-2955	266	7	e	e	NOUN
fnp-2955	266	8	,	,	PUNCT
fnp-2955	266	9	bizzotto	bizzotto	NOUN
fnp-2955	266	10	d	d	NOUN
fnp-2955	266	11	,	,	PUNCT
fnp-2955	266	12	pellicani	pellicani	ADJ
fnp-2955	266	13	r	r	NOUN
fnp-2955	266	14	,	,	PUNCT
fnp-2955	266	15	tarticchio	tarticchio	VERB
fnp-2955	266	16	g	g	NOUN
fnp-2955	266	17	,	,	PUNCT
fnp-2955	266	18	marastoni	marastoni	PROPN
fnp-2955	266	19	s	s	PART
fnp-2955	266	20	,	,	PUNCT
fnp-2955	266	21	et	et	PROPN
fnp-2955	266	22	al	al	PROPN
fnp-2955	266	23	.	.	PUNCT
fnp-2955	267	1	the	the	DET
fnp-2955	267	2	ablation	ablation	NOUN
fnp-2955	267	3	of	of	ADP
fnp-2955	267	4	the	the	DET
fnp-2955	267	5	matricellular	matricellular	ADJ
fnp-2955	267	6	protein	protein	NOUN
fnp-2955	267	7	emilin2	emilin2	NOUN
fnp-2955	267	8	causes	cause	VERB
fnp-2955	267	9	defective	defective	ADJ
fnp-2955	267	10	vascularization	vascularization	NOUN
fnp-2955	267	11	due	due	ADP
fnp-2955	267	12	to	to	ADP
fnp-2955	267	13	impaired	impaired	ADJ
fnp-2955	267	14	egfr	egfr	ADJ
fnp-2955	267	15	-	-	PUNCT
fnp-2955	267	16	dependent	dependent	ADJ
fnp-2955	267	17	il-8	il-8	NOUN
fnp-2955	267	18	production	production	NOUN
fnp-2955	267	19	affecting	affect	VERB
fnp-2955	267	20	tumor	tumor	NOUN
fnp-2955	267	21	growth	growth	NOUN
fnp-2955	267	22	.	.	PUNCT
fnp-2955	268	1	oncogene	oncogene	NOUN
fnp-2955	268	2	.	.	PUNCT
fnp-2955	269	1	2018;37(25):3399	2018;37(25):3399	NUM
fnp-2955	269	2	-	-	SYM
fnp-2955	269	3	414	414	NUM
fnp-2955	269	4	.	.	PUNCT
fnp-2955	270	1	36	36	NUM
fnp-2955	270	2	.	.	PUNCT
fnp-2955	271	1	danen	danen	PROPN
fnp-2955	271	2	eh	eh	INTJ
fnp-2955	271	3	,	,	PUNCT
fnp-2955	271	4	sonneveld	sonneveld	ADP
fnp-2955	271	5	p	p	PRON
fnp-2955	271	6	,	,	PUNCT
fnp-2955	271	7	brakebusch	brakebusch	NOUN
fnp-2955	271	8	c	c	NOUN
fnp-2955	271	9	,	,	PUNCT
fnp-2955	271	10	fassler	fassler	NOUN
fnp-2955	271	11	r	r	NOUN
fnp-2955	271	12	,	,	PUNCT
fnp-2955	271	13	sonnenberg	sonnenberg	PROPN
fnp-2955	271	14	a.	a.	NOUN
fnp-2955	271	15	the	the	DET
fnp-2955	271	16	fibronectin	fibronectin	NOUN
fnp-2955	271	17	-	-	PUNCT
fnp-2955	271	18	binding	bind	VERB
fnp-2955	271	19	integrins	integrin	NOUN
fnp-2955	271	20	alpha5beta1	alpha5beta1	NOUN
fnp-2955	271	21	and	and	CCONJ
fnp-2955	271	22	alphavbeta3	alphavbeta3	PRON
fnp-2955	271	23	differentially	differentially	ADV
fnp-2955	271	24	modulate	modulate	VERB
fnp-2955	271	25	rhoa	rhoa	PROPN
fnp-2955	271	26	-	-	PUNCT
fnp-2955	271	27	gtp	gtp	NOUN
fnp-2955	271	28	loading	loading	NOUN
fnp-2955	271	29	,	,	PUNCT
fnp-2955	271	30	organization	organization	NOUN
fnp-2955	271	31	of	of	ADP
fnp-2955	271	32	cell	cell	NOUN
fnp-2955	271	33	matrix	matrix	NOUN
fnp-2955	271	34	adhesions	adhesion	NOUN
fnp-2955	271	35	,	,	PUNCT
fnp-2955	271	36	and	and	CCONJ
fnp-2955	271	37	fibronectin	fibronectin	NOUN
fnp-2955	271	38	fibrillogenesis	fibrillogenesis	NOUN
fnp-2955	271	39	.	.	PUNCT
fnp-2955	272	1	j	j	PROPN
fnp-2955	272	2	cell	cell	NOUN
fnp-2955	272	3	biol	biol	PROPN
fnp-2955	272	4	.	.	PUNCT
fnp-2955	273	1	2002;159(6):1071	2002;159(6):1071	NUM
fnp-2955	273	2	-	-	SYM
fnp-2955	273	3	86	86	NUM
fnp-2955	273	4	.	.	PUNCT
fnp-2955	274	1	37	37	NUM
fnp-2955	274	2	.	.	PUNCT
fnp-2955	275	1	macgregor	macgregor	PROPN
fnp-2955	275	2	sharp	sharp	PROPN
fnp-2955	275	3	m	m	PROPN
fnp-2955	275	4	,	,	PUNCT
fnp-2955	275	5	saito	saito	PROPN
fnp-2955	275	6	s	s	PROPN
fnp-2955	275	7	,	,	PUNCT
fnp-2955	275	8	keable	keable	ADJ
fnp-2955	275	9	a	a	PRON
fnp-2955	275	10	,	,	PUNCT
fnp-2955	275	11	gatherer	gatherer	NOUN
fnp-2955	275	12	m	m	PROPN
fnp-2955	275	13	,	,	PUNCT
fnp-2955	275	14	aldea	aldea	PROPN
fnp-2955	275	15	r	r	NOUN
fnp-2955	275	16	,	,	PUNCT
fnp-2955	275	17	agarwal	agarwal	PROPN
fnp-2955	275	18	n	n	CCONJ
fnp-2955	275	19	,	,	PUNCT
fnp-2955	275	20	et	et	PROPN
fnp-2955	275	21	al	al	PROPN
fnp-2955	275	22	.	.	PUNCT
fnp-2955	276	1	demonstrating	demonstrate	VERB
fnp-2955	276	2	a	a	DET
fnp-2955	276	3	reduced	reduce	VERB
fnp-2955	276	4	capacity	capacity	NOUN
fnp-2955	276	5	for	for	ADP
fnp-2955	276	6	removal	removal	NOUN
fnp-2955	276	7	of	of	ADP
fnp-2955	276	8	fluid	fluid	NOUN
fnp-2955	276	9	from	from	ADP
fnp-2955	276	10	cerebral	cerebral	ADJ
fnp-2955	276	11	white	white	ADJ
fnp-2955	276	12	matter	matter	NOUN
fnp-2955	276	13	and	and	CCONJ
fnp-2955	276	14	hypoxia	hypoxia	VERB
fnp-2955	276	15	in	in	ADP
fnp-2955	276	16	areas	area	NOUN
fnp-2955	276	17	of	of	ADP
fnp-2955	276	18	white	white	ADJ
fnp-2955	276	19	matter	matter	NOUN
fnp-2955	276	20	hyperintensity	hyperintensity	NOUN
fnp-2955	276	21	associated	associate	VERB
fnp-2955	276	22	with	with	ADP
fnp-2955	276	23	age	age	NOUN
fnp-2955	276	24	and	and	CCONJ
fnp-2955	276	25	dementia	dementia	NOUN
fnp-2955	276	26	.	.	PUNCT
fnp-2955	277	1	acta	acta	PROPN
fnp-2955	277	2	neuropathol	neuropathol	PROPN
fnp-2955	277	3	commun	commun	PROPN
fnp-2955	277	4	.	.	PUNCT
fnp-2955	278	1	2020;8(1):131	2020;8(1):131	X
fnp-2955	278	2	.	.	PROPN
fnp-2955	279	1	38	38	NUM
fnp-2955	279	2	.	.	PUNCT
fnp-2955	280	1	doliana	doliana	PROPN
fnp-2955	280	2	r	r	NOUN
fnp-2955	280	3	,	,	PUNCT
fnp-2955	280	4	bot	bot	NOUN
fnp-2955	280	5	s	s	PART
fnp-2955	280	6	,	,	PUNCT
fnp-2955	280	7	mungiguerra	mungiguerra	PROPN
fnp-2955	280	8	g	g	PROPN
fnp-2955	280	9	,	,	PUNCT
fnp-2955	280	10	canton	canton	PROPN
fnp-2955	280	11	a	a	PRON
fnp-2955	280	12	,	,	PUNCT
fnp-2955	280	13	cilli	cilli	ADJ
fnp-2955	280	14	sp	sp	NOUN
fnp-2955	280	15	,	,	PUNCT
fnp-2955	280	16	colombatti	colombatti	NOUN
fnp-2955	280	17	a.	a.	NOUN
fnp-2955	280	18	isolation	isolation	NOUN
fnp-2955	280	19	and	and	CCONJ
fnp-2955	280	20	characterization	characterization	NOUN
fnp-2955	280	21	of	of	ADP
fnp-2955	280	22	emilin-2	emilin-2	NUM
fnp-2955	280	23	,	,	PUNCT
fnp-2955	280	24	a	a	DET
fnp-2955	280	25	new	new	ADJ
fnp-2955	280	26	component	component	NOUN
fnp-2955	280	27	of	of	ADP
fnp-2955	280	28	the	the	DET
fnp-2955	280	29	growing	grow	VERB
fnp-2955	280	30	emilins	emilin	NOUN
fnp-2955	280	31	family	family	NOUN
fnp-2955	280	32	and	and	CCONJ
fnp-2955	280	33	a	a	DET
fnp-2955	280	34	member	member	NOUN
fnp-2955	280	35	of	of	ADP
fnp-2955	280	36	the	the	DET
fnp-2955	280	37	emi	emi	NOUN
fnp-2955	280	38	domain	domain	NOUN
fnp-2955	280	39	-	-	PUNCT
fnp-2955	280	40	containing	contain	VERB
fnp-2955	280	41	superfamily	superfamily	NOUN
fnp-2955	280	42	.	.	PUNCT
fnp-2955	281	1	j	j	PROPN
fnp-2955	281	2	biol	biol	PROPN
fnp-2955	281	3	chem	chem	NOUN
fnp-2955	281	4	.	.	PUNCT
fnp-2955	282	1	2001;276(15):12003	2001;276(15):12003	NUM
fnp-2955	282	2	-	-	PROPN
fnp-2955	282	3	11	11	NUM
fnp-2955	282	4	.	.	NOUN
fnp-2955	283	1	39	39	NUM
fnp-2955	283	2	.	.	PUNCT
fnp-2955	284	1	amma	amma	PROPN
fnp-2955	284	2	ll	ll	PROPN
fnp-2955	284	3	,	,	PUNCT
fnp-2955	284	4	goodyear	goodyear	PROPN
fnp-2955	284	5	r	r	PROPN
fnp-2955	284	6	,	,	PUNCT
fnp-2955	284	7	faris	faris	PROPN
fnp-2955	284	8	js	js	PROPN
fnp-2955	284	9	,	,	PUNCT
fnp-2955	284	10	jones	jones	PROPN
fnp-2955	285	1	i	i	PROPN
fnp-2955	285	2	,	,	PUNCT
fnp-2955	285	3	ng	ng	PROPN
fnp-2955	285	4	l	l	PROPN
fnp-2955	285	5	,	,	PUNCT
fnp-2955	285	6	richardson	richardson	PROPN
fnp-2955	285	7	g	g	PROPN
fnp-2955	285	8	,	,	PUNCT
fnp-2955	285	9	et	et	PROPN
fnp-2955	285	10	al	al	PROPN
fnp-2955	285	11	.	.	PUNCT
fnp-2955	286	1	an	an	DET
fnp-2955	286	2	emilin	emilin	NOUN
fnp-2955	286	3	family	family	NOUN
fnp-2955	286	4	extracellular	extracellular	ADJ
fnp-2955	286	5	matrix	matrix	NOUN
fnp-2955	286	6	protein	protein	NOUN
fnp-2955	286	7	identified	identify	VERB
fnp-2955	286	8	in	in	ADP
fnp-2955	286	9	the	the	DET
fnp-2955	286	10	cochlear	cochlear	ADJ
fnp-2955	286	11	basilar	basilar	ADJ
fnp-2955	286	12	membrane	membrane	NOUN
fnp-2955	286	13	.	.	PUNCT
fnp-2955	287	1	mol	mol	ADP
fnp-2955	287	2	cell	cell	NOUN
fnp-2955	287	3	neurosci	neurosci	NOUN
fnp-2955	287	4	.	.	PUNCT
fnp-2955	288	1	2003;23(3):460	2003;23(3):460	NUM
fnp-2955	288	2	-	-	SYM
fnp-2955	288	3	72	72	NUM
fnp-2955	288	4	.	.	PUNCT
fnp-2955	289	1	40	40	NUM
fnp-2955	289	2	.	.	PUNCT
fnp-2955	290	1	okamoto	okamoto	PROPN
fnp-2955	290	2	y	y	PROPN
fnp-2955	290	3	,	,	PUNCT
fnp-2955	290	4	yamamoto	yamamoto	PROPN
fnp-2955	290	5	t	t	PROPN
fnp-2955	290	6	,	,	PUNCT
fnp-2955	290	7	kalaria	kalaria	PROPN
fnp-2955	290	8	rn	rn	PROPN
fnp-2955	290	9	,	,	PUNCT
fnp-2955	290	10	senzaki	senzaki	PROPN
fnp-2955	290	11	h	h	PROPN
fnp-2955	290	12	,	,	PUNCT
fnp-2955	290	13	maki	maki	PROPN
fnp-2955	290	14	t	t	PROPN
fnp-2955	290	15	,	,	PUNCT
fnp-2955	290	16	hase	hase	VERB
fnp-2955	290	17	y	y	PROPN
fnp-2955	290	18	,	,	PUNCT
fnp-2955	290	19	et	et	PROPN
fnp-2955	290	20	al	al	PROPN
fnp-2955	290	21	.	.	PROPN
fnp-2955	291	1	cerebral	cerebral	ADJ
fnp-2955	291	2	hypoperfusion	hypoperfusion	NOUN
fnp-2955	291	3	accelerates	accelerate	VERB
fnp-2955	291	4	cerebral	cerebral	ADJ
fnp-2955	291	5	amyloid	amyloid	NOUN
fnp-2955	291	6	angiopathy	angiopathy	NOUN
fnp-2955	291	7	and	and	CCONJ
fnp-2955	291	8	promotes	promote	VERB
fnp-2955	291	9	cortical	cortical	ADJ
fnp-2955	291	10	microinfarcts	microinfarct	NOUN
fnp-2955	291	11	.	.	PUNCT
fnp-2955	292	1	acta	acta	PROPN
fnp-2955	292	2	neuropathol	neuropathol	PROPN
fnp-2955	292	3	.	.	PUNCT
fnp-2955	293	1	2012;123(3):381	2012;123(3):381	PROPN
fnp-2955	293	2	-	-	SYM
fnp-2955	293	3	94	94	NUM
fnp-2955	293	4	.	.	PUNCT
fnp-2955	294	1	41	41	NUM
fnp-2955	294	2	.	.	PUNCT
fnp-2955	295	1	kim	kim	PROPN
fnp-2955	295	2	c	c	PROPN
fnp-2955	295	3	,	,	PUNCT
fnp-2955	295	4	ye	ye	PRON
fnp-2955	295	5	f	f	PROPN
fnp-2955	295	6	,	,	PUNCT
fnp-2955	295	7	ginsberg	ginsberg	PROPN
fnp-2955	295	8	mh	mh	PROPN
fnp-2955	295	9	.	.	PUNCT
fnp-2955	295	10	regulation	regulation	NOUN
fnp-2955	295	11	of	of	ADP
fnp-2955	295	12	integrin	integrin	NOUN
fnp-2955	295	13	activation	activation	NOUN
fnp-2955	295	14	.	.	PUNCT
fnp-2955	296	1	annu	annu	PROPN
fnp-2955	296	2	rev	rev	PROPN
fnp-2955	296	3	cell	cell	PROPN
fnp-2955	296	4	dev	dev	PROPN
fnp-2955	296	5	biol	biol	NOUN
fnp-2955	296	6	.	.	PUNCT
fnp-2955	297	1	2011;27:321	2011;27:321	NUM
fnp-2955	297	2	-	-	SYM
fnp-2955	297	3	45	45	NUM
fnp-2955	297	4	.	.	PUNCT
fnp-2955	298	1	42	42	NUM
fnp-2955	298	2	.	.	PUNCT
fnp-2955	299	1	ye	ye	PRON
fnp-2955	299	2	f	f	PROPN
fnp-2955	299	3	,	,	PUNCT
fnp-2955	299	4	lagarrigue	lagarrigue	PROPN
fnp-2955	299	5	f	f	PROPN
fnp-2955	299	6	,	,	PUNCT
fnp-2955	299	7	ginsberg	ginsberg	PROPN
fnp-2955	299	8	mh	mh	PROPN
fnp-2955	299	9	.	.	PROPN
fnp-2955	300	1	snapshot	snapshot	PROPN
fnp-2955	300	2	:	:	PUNCT
fnp-2955	300	3	talin	talin	NOUN
fnp-2955	300	4	and	and	CCONJ
fnp-2955	300	5	the	the	DET
fnp-2955	300	6	modular	modular	ADJ
fnp-2955	300	7	nature	nature	NOUN
fnp-2955	300	8	of	of	ADP
fnp-2955	300	9	the	the	DET
fnp-2955	300	10	integrin	integrin	NOUN
fnp-2955	300	11	adhesome	adhesome	NOUN
fnp-2955	300	12	.	.	PUNCT
fnp-2955	301	1	cell	cell	NOUN
fnp-2955	301	2	.	.	PUNCT
fnp-2955	302	1	2014;156(6):1340e1	2014;156(6):1340e1	NUM
fnp-2955	302	2	.	.	X
fnp-2955	303	1	43	43	NUM
fnp-2955	303	2	.	.	PUNCT
fnp-2955	304	1	calderwood	calderwood	PROPN
fnp-2955	304	2	da	da	PROPN
fnp-2955	304	3	,	,	PUNCT
fnp-2955	304	4	campbell	campbell	PROPN
fnp-2955	304	5	i	i	PROPN
fnp-2955	304	6	d	d	PROPN
fnp-2955	304	7	,	,	PUNCT
fnp-2955	304	8	critchley	critchley	PROPN
fnp-2955	304	9	dr	dr	PROPN
fnp-2955	304	10	.	.	PROPN
fnp-2955	304	11	talins	talin	NOUN
fnp-2955	304	12	and	and	CCONJ
fnp-2955	304	13	kindlins	kindlin	NOUN
fnp-2955	304	14	:	:	PUNCT
fnp-2955	304	15	partners	partner	NOUN
fnp-2955	304	16	in	in	ADP
fnp-2955	304	17	integrin	integrin	NOUN
fnp-2955	304	18	-	-	PUNCT
fnp-2955	304	19	mediated	mediate	VERB
fnp-2955	304	20	adhesion	adhesion	NOUN
fnp-2955	304	21	.	.	PUNCT
fnp-2955	305	1	nat	nat	PROPN
fnp-2955	305	2	rev	rev	VERB
fnp-2955	305	3	mol	mol	ADP
fnp-2955	305	4	cell	cell	NOUN
fnp-2955	305	5	biol	biol	NOUN
fnp-2955	305	6	.	.	PUNCT
fnp-2955	306	1	2013;14(8):503	2013;14(8):503	NUM
fnp-2955	306	2	-	-	SYM
fnp-2955	306	3	17.4	17.4	NUM
fnp-2955	306	4	.	.	PUNCT
fnp-2955	307	1	goult	goult	VERB
fnp-2955	307	2	bt	bt	PROPN
fnp-2955	307	3	,	,	PUNCT
fnp-2955	307	4	xu	xu	PROPN
fnp-2955	307	5	xp	xp	PROPN
fnp-2955	307	6	,	,	PUNCT
fnp-2955	307	7	gingras	gingras	PROPN
fnp-2955	307	8	ar	ar	PROPN
fnp-2955	307	9	,	,	PUNCT
fnp-2955	307	10	swift	swift	ADJ
fnp-2955	307	11	m	m	PROPN
fnp-2955	307	12	,	,	PUNCT
fnp-2955	307	13	patel	patel	PROPN
fnp-2955	307	14	b	b	PROPN
fnp-2955	307	15	,	,	PUNCT
fnp-2955	307	16	bate	bate	PROPN
fnp-2955	307	17	n	n	CCONJ
fnp-2955	307	18	,	,	PUNCT
fnp-2955	307	19	et	et	PROPN
fnp-2955	307	20	al	al	PROPN
fnp-2955	307	21	.	.	PROPN
fnp-2955	308	1	structural	structural	ADJ
fnp-2955	308	2	studies	study	NOUN
fnp-2955	308	3	on	on	ADP
fnp-2955	308	4	full	full	ADJ
fnp-2955	308	5	-	-	PUNCT
fnp-2955	308	6	length	length	NOUN
fnp-2955	308	7	talin1	talin1	NOUN
fnp-2955	308	8	reveal	reveal	VERB
fnp-2955	308	9	a	a	DET
fnp-2955	308	10	compact	compact	ADJ
fnp-2955	308	11	auto	auto	NOUN
fnp-2955	308	12	-	-	PUNCT
fnp-2955	308	13	inhibited	inhibit	VERB
fnp-2955	308	14	dimer	dimer	NOUN
fnp-2955	308	15	:	:	PUNCT
fnp-2955	308	16	implications	implication	NOUN
fnp-2955	308	17	for	for	ADP
fnp-2955	308	18	talin	talin	NOUN
fnp-2955	308	19	activation	activation	NOUN
fnp-2955	308	20	.	.	PUNCT
fnp-2955	309	1	j	j	PROPN
fnp-2955	309	2	struct	struct	NOUN
fnp-2955	309	3	biol	biol	PROPN
fnp-2955	309	4	.	.	PUNCT
fnp-2955	310	1	2013;184(1):21	2013;184(1):21	NUM
fnp-2955	310	2	-	-	SYM
fnp-2955	310	3	32	32	NUM
fnp-2955	310	4	.	.	PUNCT
fnp-2955	311	1	45	45	NUM
fnp-2955	311	2	.	.	NUM
fnp-2955	311	3	tadokoro	tadokoro	PROPN
fnp-2955	311	4	s	s	PROPN
fnp-2955	311	5	,	,	PUNCT
fnp-2955	311	6	shattil	shattil	PROPN
fnp-2955	311	7	sj	sj	PROPN
fnp-2955	311	8	,	,	PUNCT
fnp-2955	311	9	eto	eto	PROPN
fnp-2955	311	10	k	k	PROPN
fnp-2955	311	11	,	,	PUNCT
fnp-2955	311	12	tai	tai	PROPN
fnp-2955	311	13	v	v	NOUN
fnp-2955	311	14	,	,	PUNCT
fnp-2955	311	15	liddington	liddington	PROPN
fnp-2955	311	16	rc	rc	PROPN
fnp-2955	311	17	,	,	PUNCT
fnp-2955	311	18	de	de	X
fnp-2955	311	19	pereda	pereda	PROPN
fnp-2955	311	20	jm	jm	PROPN
fnp-2955	311	21	,	,	PUNCT
fnp-2955	311	22	et	et	PROPN
fnp-2955	311	23	al	al	PROPN
fnp-2955	311	24	.	.	PROPN
fnp-2955	312	1	talin	talin	PROPN
fnp-2955	312	2	binding	bind	VERB
fnp-2955	312	3	to	to	AUX
fnp-2955	312	4	integrin	integrin	VERB
fnp-2955	312	5	beta	beta	NOUN
fnp-2955	312	6	tails	tail	NOUN
fnp-2955	312	7	:	:	PUNCT
fnp-2955	312	8	a	a	DET
fnp-2955	312	9	final	final	ADJ
fnp-2955	312	10	common	common	ADJ
fnp-2955	312	11	step	step	NOUN
fnp-2955	312	12	in	in	ADP
fnp-2955	312	13	integrin	integrin	NOUN
fnp-2955	312	14	activation	activation	NOUN
fnp-2955	312	15	.	.	PUNCT
fnp-2955	313	1	science	science	NOUN
fnp-2955	313	2	.	.	PUNCT
fnp-2955	314	1	2003;302(5642):103	2003;302(5642):103	NUM
fnp-2955	314	2	-	-	SYM
fnp-2955	314	3	6	6	NUM
fnp-2955	314	4	.	.	NOUN
fnp-2955	314	5	46	46	NUM
fnp-2955	314	6	.	.	PUNCT
fnp-2955	315	1	matter	matter	PROPN
fnp-2955	315	2	ml	ml	NOUN
fnp-2955	315	3	,	,	PUNCT
fnp-2955	316	1	zhang	zhang	PROPN
fnp-2955	316	2	z	z	PROPN
fnp-2955	316	3	,	,	PUNCT
fnp-2955	316	4	nordstedt	nordstedt	PROPN
fnp-2955	316	5	c	c	PROPN
fnp-2955	316	6	,	,	PUNCT
fnp-2955	316	7	ruoslahti	ruoslahti	PROPN
fnp-2955	316	8	e.	e.	PROPN
fnp-2955	317	1	the	the	DET
fnp-2955	317	2	alpha5beta1	alpha5beta1	PROPN
fnp-2955	317	3	integrin	integrin	NOUN
fnp-2955	317	4	mediates	mediate	VERB
fnp-2955	317	5	elimination	elimination	NOUN
fnp-2955	317	6	of	of	ADP
fnp-2955	317	7	amyloid	amyloid	NOUN
fnp-2955	317	8	-	-	PUNCT
fnp-2955	317	9	beta	beta	NOUN
fnp-2955	317	10	peptide	peptide	NOUN
fnp-2955	317	11	and	and	CCONJ
fnp-2955	317	12	protects	protect	VERB
fnp-2955	317	13	against	against	ADP
fnp-2955	317	14	apoptosis	apoptosis	NOUN
fnp-2955	317	15	.	.	PUNCT
fnp-2955	318	1	j	j	PROPN
fnp-2955	318	2	cell	cell	PROPN
fnp-2955	318	3	bio	bio	PROPN
fnp-2955	318	4	.	.	PUNCT
fnp-2955	319	1	1998;141(4):1019	1998;141(4):1019	NUM
fnp-2955	319	2	-	-	SYM
fnp-2955	319	3	30	30	NUM
fnp-2955	319	4	.	.	PUNCT
fnp-2955	320	1	47	47	NUM
fnp-2955	320	2	.	.	PUNCT
fnp-2955	321	1	tan	tan	PROPN
fnp-2955	321	2	cl	cl	PROPN
fnp-2955	321	3	,	,	PUNCT
fnp-2955	321	4	kwok	kwok	PROPN
fnp-2955	321	5	jc	jc	PROPN
fnp-2955	321	6	,	,	PUNCT
fnp-2955	321	7	patani	patani	ADJ
fnp-2955	321	8	r	r	NOUN
fnp-2955	321	9	,	,	PUNCT
fnp-2955	321	10	ffrench	ffrench	ADJ
fnp-2955	321	11	-	-	PUNCT
fnp-2955	321	12	constant	constant	ADJ
fnp-2955	321	13	c	c	NOUN
fnp-2955	321	14	,	,	PUNCT
fnp-2955	321	15	chandran	chandran	PROPN
fnp-2955	321	16	s	s	PROPN
fnp-2955	321	17	,	,	PUNCT
fnp-2955	321	18	fawcett	fawcett	PROPN
fnp-2955	321	19	jw	jw	PROPN
fnp-2955	321	20	.	.	PROPN
fnp-2955	321	21	integrin	integrin	PROPN
fnp-2955	321	22	activation	activation	NOUN
fnp-2955	321	23	promotes	promote	VERB
fnp-2955	321	24	axon	axon	ADJ
fnp-2955	321	25	growth	growth	NOUN
fnp-2955	321	26	on	on	ADP
fnp-2955	321	27	inhibitory	inhibitory	ADJ
fnp-2955	321	28	chondroitin	chondroitin	NOUN
fnp-2955	321	29	sulfate	sulfate	NOUN
fnp-2955	321	30	proteoglycans	proteoglycan	NOUN
fnp-2955	321	31	by	by	ADP
fnp-2955	321	32	enhancing	enhance	VERB
fnp-2955	321	33	integrin	integrin	NOUN
fnp-2955	321	34	signaling	signal	VERB
fnp-2955	321	35	.	.	PUNCT
fnp-2955	322	1	j	j	PROPN
fnp-2955	322	2	neurosci	neurosci	PROPN
fnp-2955	322	3	.	.	PUNCT
fnp-2955	323	1	2011;31(17):6289	2011;31(17):6289	NUM
fnp-2955	323	2	-	-	SYM
fnp-2955	323	3	95	95	NUM
fnp-2955	323	4	.	.	PUNCT
fnp-2955	324	1	48	48	NUM
fnp-2955	324	2	.	.	PUNCT
fnp-2955	325	1	lambert	lambert	PROPN
fnp-2955	325	2	jc	jc	PROPN
fnp-2955	325	3	,	,	PUNCT
fnp-2955	325	4	heath	heath	PROPN
fnp-2955	325	5	s	s	PROPN
fnp-2955	325	6	,	,	PUNCT
fnp-2955	325	7	even	even	ADV
fnp-2955	325	8	g	g	PROPN
fnp-2955	325	9	,	,	PUNCT
fnp-2955	325	10	campion	campion	NOUN
fnp-2955	325	11	d	d	PROPN
fnp-2955	325	12	,	,	PUNCT
fnp-2955	325	13	sleegers	sleeger	NOUN
fnp-2955	325	14	k	k	PROPN
fnp-2955	325	15	,	,	PUNCT
fnp-2955	325	16	hiltunen	hiltunen	PROPN
fnp-2955	325	17	m	m	PROPN
fnp-2955	325	18	,	,	PUNCT
fnp-2955	325	19	et	et	PROPN
fnp-2955	325	20	al	al	PROPN
fnp-2955	325	21	.	.	PUNCT
fnp-2955	325	22	genome	genome	NOUN
fnp-2955	325	23	-	-	PUNCT
fnp-2955	325	24	wide	wide	ADJ
fnp-2955	325	25	association	association	NOUN
fnp-2955	325	26	study	study	NOUN
fnp-2955	325	27	identifies	identify	VERB
fnp-2955	325	28	variants	variant	NOUN
fnp-2955	325	29	at	at	ADP
fnp-2955	325	30	clu	clu	PROPN
fnp-2955	325	31	and	and	CCONJ
fnp-2955	325	32	cr1	cr1	PROPN
fnp-2955	325	33	associated	associate	VERB
fnp-2955	325	34	with	with	ADP
fnp-2955	325	35	alzheimer	alzheimer	PROPN
fnp-2955	325	36	's	's	PART
fnp-2955	325	37	disease	disease	NOUN
fnp-2955	325	38	.	.	PUNCT
fnp-2955	326	1	nat	nat	PROPN
fnp-2955	326	2	genet	genet	PROPN
fnp-2955	326	3	.	.	PUNCT
fnp-2955	327	1	2009;41(10):1094	2009;41(10):1094	NUM
fnp-2955	327	2	-	-	SYM
fnp-2955	327	3	9	9	NUM
fnp-2955	327	4	.	.	NUM
fnp-2955	327	5	49	49	NUM
fnp-2955	327	6	.	.	PUNCT
fnp-2955	328	1	harold	harold	PROPN
fnp-2955	328	2	d	d	PROPN
fnp-2955	328	3	,	,	PUNCT
fnp-2955	328	4	abraham	abraham	PROPN
fnp-2955	328	5	r	r	PROPN
fnp-2955	328	6	,	,	PUNCT
fnp-2955	328	7	hollingworth	hollingworth	NOUN
fnp-2955	328	8	p	p	NOUN
fnp-2955	328	9	,	,	PUNCT
fnp-2955	328	10	sims	sim	NOUN
fnp-2955	328	11	r	r	NOUN
fnp-2955	328	12	,	,	PUNCT
fnp-2955	328	13	gerrish	gerrish	VERB
fnp-2955	328	14	a	a	PRON
fnp-2955	328	15	,	,	PUNCT
fnp-2955	328	16	hamshere	hamshere	NOUN
fnp-2955	328	17	ml	ml	NOUN
fnp-2955	328	18	,	,	PUNCT
fnp-2955	328	19	et	et	PROPN
fnp-2955	328	20	al	al	PROPN
fnp-2955	328	21	.	.	PUNCT
fnp-2955	328	22	genome	genome	NOUN
fnp-2955	328	23	-	-	PUNCT
fnp-2955	328	24	wide	wide	ADJ
fnp-2955	328	25	association	association	NOUN
fnp-2955	328	26	study	study	NOUN
fnp-2955	328	27	identifies	identify	VERB
fnp-2955	328	28	variants	variant	NOUN
fnp-2955	328	29	at	at	ADP
fnp-2955	328	30	clu	clu	PROPN
fnp-2955	328	31	and	and	CCONJ
fnp-2955	328	32	picalm	picalm	NOUN
fnp-2955	328	33	associated	associate	VERB
fnp-2955	328	34	with	with	ADP
fnp-2955	328	35	alzheimer	alzheimer	PROPN
fnp-2955	328	36	's	's	PART
fnp-2955	328	37	disease	disease	NOUN
fnp-2955	328	38	.	.	PUNCT
fnp-2955	329	1	nat	nat	PROPN
fnp-2955	329	2	genet	genet	PROPN
fnp-2955	329	3	.	.	PUNCT
fnp-2955	330	1	2009;41(10):1088	2009;41(10):1088	NUM
fnp-2955	330	2	-	-	SYM
fnp-2955	330	3	93	93	NUM
fnp-2955	330	4	.	.	PUNCT
fnp-2955	331	1	50	50	NUM
fnp-2955	331	2	.	.	PUNCT
fnp-2955	332	1	wojtas	wojtas	PROPN
fnp-2955	332	2	am	be	AUX
fnp-2955	332	3	,	,	PUNCT
fnp-2955	332	4	kang	kang	PROPN
fnp-2955	332	5	ss	ss	PROPN
fnp-2955	332	6	,	,	PUNCT
fnp-2955	332	7	olley	olley	PROPN
fnp-2955	332	8	bm	bm	PROPN
fnp-2955	332	9	,	,	PUNCT
fnp-2955	332	10	gatherer	gatherer	PROPN
fnp-2955	332	11	m	m	PROPN
fnp-2955	332	12	,	,	PUNCT
fnp-2955	332	13	shinohara	shinohara	PROPN
fnp-2955	332	14	m	m	PROPN
fnp-2955	332	15	,	,	PUNCT
fnp-2955	332	16	lozano	lozano	PROPN
fnp-2955	332	17	pa	pa	PROPN
fnp-2955	332	18	,	,	PUNCT
fnp-2955	332	19	et	et	PROPN
fnp-2955	332	20	al	al	PROPN
fnp-2955	332	21	.	.	PUNCT
fnp-2955	332	22	loss	loss	PROPN
fnp-2955	332	23	of	of	ADP
fnp-2955	332	24	clusterin	clusterin	ADJ
fnp-2955	332	25	shifts	shift	NOUN
fnp-2955	332	26	amyloid	amyloid	VERB
fnp-2955	332	27	deposition	deposition	NOUN
fnp-2955	332	28	to	to	ADP
fnp-2955	332	29	the	the	DET
fnp-2955	332	30	cerebrovasculature	cerebrovasculature	NOUN
fnp-2955	332	31	via	via	ADP
fnp-2955	332	32	disruption	disruption	NOUN
fnp-2955	332	33	of	of	ADP
fnp-2955	332	34	perivascular	perivascular	ADJ
fnp-2955	332	35	drainage	drainage	NOUN
fnp-2955	332	36	pathways	pathway	NOUN
fnp-2955	332	37	.	.	PUNCT
fnp-2955	333	1	proc	proc	PROPN
fnp-2955	333	2	natl	natl	PROPN
fnp-2955	333	3	acad	acad	PROPN
fnp-2955	333	4	sci	sci	PROPN
fnp-2955	333	5	u	u	PROPN
fnp-2955	333	6	s	s	VERB
fnp-2955	333	7	a	a	PRON
fnp-2955	333	8	.	.	PUNCT
fnp-2955	334	1	2017;114(33):e6962	2017;114(33):e6962	NUM
fnp-2955	334	2	-	-	PUNCT
fnp-2955	334	3	e71	e71	NOUN
fnp-2955	334	4	.	.	PUNCT
fnp-2955	335	1	51	51	NUM
fnp-2955	335	2	.	.	PUNCT
fnp-2955	336	1	saito	saito	PROPN
fnp-2955	336	2	s	s	PROPN
fnp-2955	336	3	,	,	PUNCT
fnp-2955	336	4	ihara	ihara	PROPN
fnp-2955	336	5	m.	m.	NOUN
fnp-2955	336	6	new	new	ADJ
fnp-2955	336	7	therapeutic	therapeutic	ADJ
fnp-2955	336	8	approaches	approach	NOUN
fnp-2955	336	9	for	for	ADP
fnp-2955	336	10	alzheimer	alzheimer	NOUN
fnp-2955	336	11	's	's	PART
fnp-2955	336	12	disease	disease	NOUN
fnp-2955	336	13	and	and	CCONJ
fnp-2955	336	14	cerebral	cerebral	ADJ
fnp-2955	336	15	amyloid	amyloid	NOUN
fnp-2955	336	16	angiopathy	angiopathy	NOUN
fnp-2955	336	17	.	.	PUNCT
fnp-2955	337	1	front	front	ADJ
fnp-2955	337	2	aging	age	VERB
fnp-2955	337	3	neurosci	neurosci	NOUN
fnp-2955	337	4	.	.	PUNCT
fnp-2955	338	1	2014;6:290	2014;6:290	NUM
fnp-2955	338	2	.	.	PUNCT
fnp-2955	339	1	52	52	NUM
fnp-2955	339	2	.	.	PUNCT
fnp-2955	340	1	qiu	qiu	PROPN
fnp-2955	340	2	wq	wq	PROPN
fnp-2955	340	3	,	,	PUNCT
fnp-2955	340	4	folstein	folstein	ADV
fnp-2955	340	5	mf	mf	X
fnp-2955	340	6	.	.	PUNCT
fnp-2955	340	7	insulin	insulin	NOUN
fnp-2955	340	8	,	,	PUNCT
fnp-2955	340	9	insulin	insulin	NOUN
fnp-2955	340	10	-	-	PUNCT
fnp-2955	340	11	degrading	degrade	VERB
fnp-2955	340	12	enzyme	enzyme	NOUN
fnp-2955	340	13	and	and	CCONJ
fnp-2955	340	14	amyloid	amyloid	NOUN
fnp-2955	340	15	-	-	PUNCT
fnp-2955	340	16	beta	beta	NOUN
fnp-2955	340	17	peptide	peptide	NOUN
fnp-2955	340	18	in	in	ADP
fnp-2955	340	19	alzheimer	alzheimer	PROPN
fnp-2955	340	20	's	's	PART
fnp-2955	340	21	disease	disease	NOUN
fnp-2955	340	22	:	:	PUNCT
fnp-2955	340	23	review	review	NOUN
fnp-2955	340	24	and	and	CCONJ
fnp-2955	340	25	hypothesis	hypothesis	NOUN
fnp-2955	340	26	.	.	PUNCT
fnp-2955	341	1	neurobiol	neurobiol	PROPN
fnp-2955	341	2	aging	aging	NOUN
fnp-2955	341	3	.	.	PUNCT
fnp-2955	342	1	2006;27(2):190	2006;27(2):190	NUM
fnp-2955	342	2	-	-	SYM
fnp-2955	342	3	8	8	NUM
fnp-2955	342	4	.	.	X
fnp-2955	342	5	53	53	NUM
fnp-2955	342	6	.	.	PUNCT
fnp-2955	343	1	craft	craft	PROPN
fnp-2955	343	2	s	s	PROPN
fnp-2955	343	3	,	,	PUNCT
fnp-2955	343	4	watson	watson	PROPN
fnp-2955	343	5	gs	gs	PROPN
fnp-2955	343	6	.	.	PUNCT
fnp-2955	343	7	insulin	insulin	NOUN
fnp-2955	343	8	and	and	CCONJ
fnp-2955	343	9	neurodegenerative	neurodegenerative	ADJ
fnp-2955	343	10	disease	disease	NOUN
fnp-2955	343	11	:	:	PUNCT
fnp-2955	343	12	shared	share	VERB
fnp-2955	343	13	and	and	CCONJ
fnp-2955	343	14	specific	specific	ADJ
fnp-2955	343	15	mechanisms	mechanism	NOUN
fnp-2955	343	16	.	.	PUNCT
fnp-2955	344	1	lancet	lancet	PROPN
fnp-2955	344	2	neurol	neurol	PROPN
fnp-2955	344	3	.	.	PUNCT
fnp-2955	345	1	2004;3(3):169	2004;3(3):169	NUM
fnp-2955	345	2	-	-	SYM
fnp-2955	345	3	78	78	NUM
fnp-2955	345	4	.	.	PUNCT
fnp-2955	346	1	54	54	NUM
fnp-2955	346	2	.	.	PUNCT
fnp-2955	347	1	farris	farris	PROPN
fnp-2955	347	2	w	w	PROPN
fnp-2955	347	3	,	,	PUNCT
fnp-2955	347	4	mansourian	mansourian	PROPN
fnp-2955	347	5	s	s	PROPN
fnp-2955	347	6	,	,	PUNCT
fnp-2955	347	7	chang	chang	PROPN
fnp-2955	347	8	y	y	PROPN
fnp-2955	347	9	,	,	PUNCT
fnp-2955	347	10	lindsley	lindsley	PROPN
fnp-2955	347	11	l	l	NOUN
fnp-2955	347	12	,	,	PUNCT
fnp-2955	347	13	eckman	eckman	NOUN
fnp-2955	347	14	ea	ea	PROPN
fnp-2955	347	15	,	,	PUNCT
fnp-2955	347	16	frosch	frosch	PROPN
fnp-2955	347	17	mp	mp	PROPN
fnp-2955	347	18	,	,	PUNCT
fnp-2955	347	19	et	et	PROPN
fnp-2955	347	20	al	al	PROPN
fnp-2955	347	21	.	.	PUNCT
fnp-2955	348	1	insulin	insulin	NOUN
fnp-2955	348	2	-	-	PUNCT
fnp-2955	348	3	degrading	degrade	VERB
fnp-2955	348	4	enzyme	enzyme	NOUN
fnp-2955	348	5	regulates	regulate	VERB
fnp-2955	348	6	the	the	DET
fnp-2955	348	7	levels	level	NOUN
fnp-2955	348	8	of	of	ADP
fnp-2955	348	9	insulin	insulin	NOUN
fnp-2955	348	10	,	,	PUNCT
fnp-2955	348	11	amyloid	amyloid	NOUN
fnp-2955	348	12	beta	beta	NOUN
fnp-2955	348	13	-	-	PUNCT
fnp-2955	348	14	protein	protein	NOUN
fnp-2955	348	15	,	,	PUNCT
fnp-2955	348	16	and	and	CCONJ
fnp-2955	348	17	the	the	DET
fnp-2955	348	18	beta	beta	NOUN
fnp-2955	348	19	-	-	PUNCT
fnp-2955	348	20	amyloid	amyloid	NOUN
fnp-2955	348	21	precursor	precursor	NOUN
fnp-2955	348	22	protein	protein	NOUN
fnp-2955	348	23	intracellular	intracellular	ADJ
fnp-2955	348	24	domain	domain	NOUN
fnp-2955	348	25	in	in	ADP
fnp-2955	348	26	vivo	vivo	NOUN
fnp-2955	348	27	.	.	PUNCT
fnp-2955	349	1	proc	proc	PROPN
fnp-2955	349	2	natl	natl	PROPN
fnp-2955	349	3	acad	acad	PROPN
fnp-2955	349	4	sci	sci	PROPN
fnp-2955	349	5	u	u	PROPN
fnp-2955	349	6	s	s	NOUN
fnp-2955	349	7	a.	a.	NOUN
fnp-2955	349	8	2003;100(7):4162	2003;100(7):4162	NUM
fnp-2955	349	9	-	-	SYM
fnp-2955	349	10	7	7	NUM
fnp-2955	349	11	.	.	NUM
fnp-2955	349	12	55	55	NUM
fnp-2955	349	13	.	.	PUNCT
fnp-2955	350	1	leissring	leissring	PROPN
fnp-2955	350	2	ma	ma	PROPN
fnp-2955	350	3	,	,	PUNCT
fnp-2955	350	4	farris	farris	PROPN
fnp-2955	350	5	w	w	PROPN
fnp-2955	350	6	,	,	PUNCT
fnp-2955	350	7	chang	chang	PROPN
fnp-2955	350	8	ay	ay	PROPN
fnp-2955	350	9	,	,	PUNCT
fnp-2955	350	10	walsh	walsh	PROPN
fnp-2955	350	11	dm	dm	PROPN
fnp-2955	350	12	,	,	PUNCT
fnp-2955	350	13	wu	wu	PROPN
fnp-2955	350	14	x	x	PROPN
fnp-2955	350	15	,	,	PUNCT
fnp-2955	350	16	sun	sun	PROPN
fnp-2955	350	17	x	x	AUX
fnp-2955	350	18	,	,	PUNCT
fnp-2955	350	19	et	et	PROPN
fnp-2955	350	20	al	al	PROPN
fnp-2955	350	21	.	.	PROPN
fnp-2955	350	22	enhanced	enhance	VERB
fnp-2955	350	23	proteolysis	proteolysis	NOUN
fnp-2955	350	24	of	of	ADP
fnp-2955	350	25	beta	beta	NOUN
fnp-2955	350	26	-	-	PUNCT
fnp-2955	350	27	amyloid	amyloid	NOUN
fnp-2955	350	28	in	in	ADP
fnp-2955	350	29	app	app	NOUN
fnp-2955	350	30	transgenic	transgenic	NOUN
fnp-2955	350	31	mice	mouse	NOUN
fnp-2955	350	32	prevents	prevent	VERB
fnp-2955	350	33	plaque	plaque	NOUN
fnp-2955	350	34	formation	formation	NOUN
fnp-2955	350	35	,	,	PUNCT
fnp-2955	350	36	secondary	secondary	ADJ
fnp-2955	350	37	pathology	pathology	NOUN
fnp-2955	350	38	,	,	PUNCT
fnp-2955	350	39	and	and	CCONJ
fnp-2955	350	40	premature	premature	ADJ
fnp-2955	350	41	death	death	NOUN
fnp-2955	350	42	.	.	PUNCT
fnp-2955	351	1	neuron	neuron	PROPN
fnp-2955	351	2	.	.	PUNCT
fnp-2955	352	1	2003;40(6):1087	2003;40(6):1087	NUM
fnp-2955	352	2	-	-	SYM
fnp-2955	352	3	93	93	NUM
fnp-2955	352	4	.	.	PUNCT
fnp-2955	353	1	56	56	NUM
fnp-2955	353	2	.	.	X
fnp-2955	353	3	morelli	morelli	PROPN
fnp-2955	353	4	l	l	PROPN
fnp-2955	353	5	,	,	PUNCT
fnp-2955	353	6	llovera	llovera	ADJ
fnp-2955	353	7	re	re	ADP
fnp-2955	353	8	,	,	PUNCT
fnp-2955	353	9	mathov	mathov	PROPN
fnp-2955	353	10	i	i	PROPN
fnp-2955	353	11	,	,	PUNCT
fnp-2955	353	12	lue	lue	PROPN
fnp-2955	353	13	lf	lf	PROPN
fnp-2955	353	14	,	,	PUNCT
fnp-2955	353	15	frangione	frangione	NOUN
fnp-2955	353	16	b	b	PROPN
fnp-2955	353	17	,	,	PUNCT
fnp-2955	353	18	ghiso	ghiso	PROPN
fnp-2955	353	19	j	j	PROPN
fnp-2955	353	20	,	,	PUNCT
fnp-2955	353	21	et	et	PROPN
fnp-2955	353	22	al	al	PROPN
fnp-2955	353	23	.	.	PUNCT
fnp-2955	354	1	insulin	insulin	NOUN
fnp-2955	354	2	-	-	PUNCT
fnp-2955	354	3	degrading	degrade	VERB
fnp-2955	354	4	enzyme	enzyme	NOUN
fnp-2955	354	5	in	in	ADP
fnp-2955	354	6	brain	brain	NOUN
fnp-2955	354	7	microvessels	microvessel	NOUN
fnp-2955	354	8	:	:	PUNCT
fnp-2955	354	9	proteolysis	proteolysis	NOUN
fnp-2955	354	10	of	of	ADP
fnp-2955	354	11	amyloid	amyloid	NOUN
fnp-2955	354	12	{	{	PUNCT
fnp-2955	354	13	beta	beta	NOUN
fnp-2955	354	14	}	}	PUNCT
fnp-2955	354	15	vasculotropic	vasculotropic	NOUN
fnp-2955	354	16	variants	variant	NOUN
fnp-2955	354	17	and	and	CCONJ
fnp-2955	354	18	reduced	reduced	ADJ
fnp-2955	354	19	activity	activity	NOUN
fnp-2955	354	20	in	in	ADP
fnp-2955	354	21	cerebral	cerebral	ADJ
fnp-2955	354	22	amyloid	amyloid	NOUN
fnp-2955	354	23	angiopathy	angiopathy	NOUN
fnp-2955	354	24	.	.	PUNCT
fnp-2955	355	1	j	j	PROPN
fnp-2955	355	2	biol	biol	PROPN
fnp-2955	355	3	chem	chem	NOUN
fnp-2955	355	4	.	.	PUNCT
fnp-2955	356	1	2004;279(53):56004	2004;279(53):56004	NUM
fnp-2955	356	2	-	-	SYM
fnp-2955	356	3	13	13	NUM
fnp-2955	356	4	.	.	PUNCT
fnp-2955	357	1	57	57	NUM
fnp-2955	357	2	.	.	X
fnp-2955	357	3	perry	perry	PROPN
fnp-2955	357	4	rt	rt	PROPN
fnp-2955	357	5	,	,	PUNCT
fnp-2955	357	6	gearhart	gearhart	PROPN
fnp-2955	357	7	da	da	PROPN
fnp-2955	357	8	,	,	PUNCT
fnp-2955	357	9	wiener	wiener	NOUN
fnp-2955	357	10	hw	hw	PROPN
fnp-2955	357	11	,	,	PUNCT
fnp-2955	357	12	harrell	harrell	PROPN
fnp-2955	357	13	le	le	PROPN
fnp-2955	357	14	,	,	PUNCT
fnp-2955	357	15	barton	barton	PROPN
fnp-2955	357	16	jc	jc	PROPN
fnp-2955	357	17	,	,	PUNCT
fnp-2955	357	18	kutlar	kutlar	ADJ
fnp-2955	357	19	a	a	PRON
fnp-2955	357	20	,	,	PUNCT
fnp-2955	357	21	et	et	PROPN
fnp-2955	357	22	al	al	PROPN
fnp-2955	357	23	.	.	PROPN
fnp-2955	357	24	hemoglobin	hemoglobin	PROPN
fnp-2955	357	25	binding	bind	VERB
fnp-2955	357	26	to	to	ADP
fnp-2955	357	27	a	a	DET
fnp-2955	357	28	beta	beta	NOUN
fnp-2955	357	29	and	and	CCONJ
fnp-2955	357	30	hbg2	hbg2	PROPN
fnp-2955	357	31	snp	snp	PROPN
fnp-2955	357	32	association	association	PROPN
fnp-2955	357	33	suggest	suggest	VERB
fnp-2955	357	34	a	a	DET
fnp-2955	357	35	role	role	NOUN
fnp-2955	357	36	in	in	ADP
fnp-2955	357	37	alzheimer	alzheimer	PROPN
fnp-2955	357	38	's	's	PART
fnp-2955	357	39	disease	disease	NOUN
fnp-2955	357	40	.	.	PUNCT
fnp-2955	358	1	neurobiol	neurobiol	PROPN
fnp-2955	358	2	aging	aging	NOUN
fnp-2955	358	3	.	.	PUNCT
fnp-2955	359	1	2008;29(2):185	2008;29(2):185	NUM
fnp-2955	359	2	-	-	PUNCT
fnp-2955	359	3	93	93	NUM
fnp-2955	359	4	.	.	PUNCT
fnp-2955	360	1	58	58	NUM
fnp-2955	360	2	.	.	PUNCT
fnp-2955	361	1	davis	davis	PROPN
fnp-2955	361	2	j	j	PROPN
fnp-2955	361	3	,	,	PUNCT
fnp-2955	361	4	xu	xu	PROPN
fnp-2955	362	1	f	f	PROPN
fnp-2955	362	2	,	,	PUNCT
fnp-2955	362	3	miao	miao	PROPN
fnp-2955	362	4	j	j	PROPN
fnp-2955	362	5	,	,	PUNCT
fnp-2955	362	6	previti	previti	NOUN
fnp-2955	362	7	ml	ml	PROPN
fnp-2955	362	8	,	,	PUNCT
fnp-2955	362	9	romanov	romanov	PROPN
fnp-2955	362	10	g	g	PROPN
fnp-2955	362	11	,	,	PUNCT
fnp-2955	362	12	ziegler	ziegler	PROPN
fnp-2955	362	13	k	k	PROPN
fnp-2955	362	14	,	,	PUNCT
fnp-2955	362	15	et	et	PROPN
fnp-2955	362	16	al	al	PROPN
fnp-2955	362	17	.	.	PROPN
fnp-2955	362	18	deficient	deficient	ADJ
fnp-2955	362	19	cerebral	cerebral	ADJ
fnp-2955	362	20	clearance	clearance	NOUN
fnp-2955	362	21	of	of	ADP
fnp-2955	362	22	vasculotropic	vasculotropic	ADJ
fnp-2955	362	23	mutant	mutant	ADJ
fnp-2955	362	24	dutch	dutch	PROPN
fnp-2955	362	25	/	/	SYM
fnp-2955	362	26	iowa	iowa	PROPN
fnp-2955	362	27	double	double	ADJ
fnp-2955	362	28	aβ	aβ	NOUN
fnp-2955	362	29	in	in	ADP
fnp-2955	362	30	human	human	ADJ
fnp-2955	362	31	aβpp	aβpp	NOUN
fnp-2955	362	32	transgenic	transgenic	NOUN
fnp-2955	362	33	mice	mouse	NOUN
fnp-2955	362	34	.	.	PUNCT
fnp-2955	363	1	neurobiol	neurobiol	PROPN
fnp-2955	363	2	aging	aging	NOUN
fnp-2955	363	3	.	.	PUNCT
fnp-2955	364	1	2006;27(7):946	2006;27(7):946	NUM
fnp-2955	364	2	-	-	SYM
fnp-2955	364	3	54	54	NUM
fnp-2955	364	4	.	.	PUNCT
fnp-2955	365	1	59	59	NUM
fnp-2955	365	2	.	.	PUNCT
fnp-2955	366	1	kam	kam	PROPN
fnp-2955	366	2	cy	cy	PROPN
fnp-2955	366	3	,	,	PUNCT
fnp-2955	366	4	dubash	dubash	NOUN
fnp-2955	366	5	ad	ad	NOUN
fnp-2955	366	6	,	,	PUNCT
fnp-2955	366	7	magistrati	magistrati	NOUN
fnp-2955	366	8	e	e	NOUN
fnp-2955	366	9	,	,	PUNCT
fnp-2955	366	10	polo	polo	NOUN
fnp-2955	366	11	s	s	PART
fnp-2955	366	12	,	,	PUNCT
fnp-2955	366	13	satchell	satchell	PROPN
fnp-2955	366	14	kjf	kjf	PROPN
fnp-2955	366	15	,	,	PUNCT
fnp-2955	366	16	sheikh	sheikh	PROPN
fnp-2955	366	17	f	f	PROPN
fnp-2955	366	18	,	,	PUNCT
fnp-2955	366	19	et	et	PROPN
fnp-2955	366	20	al	al	PROPN
fnp-2955	366	21	.	.	PROPN
fnp-2955	366	22	desmoplakin	desmoplakin	PROPN
fnp-2955	366	23	maintains	maintain	VERB
fnp-2955	366	24	gap	gap	NOUN
fnp-2955	366	25	junctions	junction	NOUN
fnp-2955	366	26	by	by	ADP
fnp-2955	366	27	inhibiting	inhibit	VERB
fnp-2955	366	28	ras	ras	NOUN
fnp-2955	366	29	/	/	SYM
fnp-2955	366	30	mapk	mapk	NOUN
fnp-2955	366	31	and	and	CCONJ
fnp-2955	366	32	lysosomal	lysosomal	ADJ
fnp-2955	366	33	degradation	degradation	NOUN
fnp-2955	366	34	of	of	ADP
fnp-2955	366	35	connexin-43	connexin-43	PROPN
fnp-2955	366	36	.	.	PROPN
fnp-2955	366	37	j	j	PROPN
fnp-2955	366	38	cell	cell	PROPN
fnp-2955	366	39	biol	biol	PROPN
fnp-2955	366	40	.	.	PUNCT
fnp-2955	367	1	2018;217(9):3219	2018;217(9):3219	NUM
fnp-2955	367	2	-	-	SYM
fnp-2955	367	3	35	35	NUM
fnp-2955	367	4	.	.	PUNCT
fnp-2955	368	1	60	60	NUM
fnp-2955	368	2	.	.	PUNCT
fnp-2955	369	1	ebata	ebata	PROPN
fnp-2955	369	2	n	n	CCONJ
fnp-2955	369	3	,	,	PUNCT
fnp-2955	369	4	nodasaka	nodasaka	PROPN
fnp-2955	369	5	y	y	PROPN
fnp-2955	369	6	,	,	PUNCT
fnp-2955	369	7	sawa	sawa	PROPN
fnp-2955	369	8	y	y	PROPN
fnp-2955	369	9	,	,	PUNCT
fnp-2955	369	10	yamaoka	yamaoka	PROPN
fnp-2955	369	11	y	y	PROPN
fnp-2955	369	12	,	,	PUNCT
fnp-2955	369	13	makino	makino	PROPN
fnp-2955	369	14	s	s	PROPN
fnp-2955	369	15	,	,	PUNCT
fnp-2955	369	16	totsuka	totsuka	PROPN
fnp-2955	369	17	y	y	PROPN
fnp-2955	369	18	,	,	PUNCT
fnp-2955	369	19	et	et	PROPN
fnp-2955	369	20	al	al	PROPN
fnp-2955	369	21	.	.	PROPN
fnp-2955	369	22	desmoplakin	desmoplakin	PROPN
fnp-2955	369	23	as	as	ADP
fnp-2955	369	24	a	a	DET
fnp-2955	369	25	specific	specific	ADJ
fnp-2955	369	26	marker	marker	NOUN
fnp-2955	369	27	of	of	ADP
fnp-2955	369	28	lymphatic	lymphatic	ADJ
fnp-2955	369	29	vessels	vessel	NOUN
fnp-2955	369	30	.	.	PUNCT
fnp-2955	370	1	microvasc	microvasc	PROPN
fnp-2955	370	2	res	re	NOUN
fnp-2955	370	3	.	.	PUNCT
fnp-2955	371	1	2001;61(1):40	2001;61(1):40	NUM
fnp-2955	371	2	-	-	SYM
fnp-2955	371	3	8	8	NUM
fnp-2955	371	4	.	.	NOUN
fnp-2955	372	1	61	61	NUM
fnp-2955	372	2	.	.	PUNCT
fnp-2955	373	1	engelhardt	engelhardt	PROPN
fnp-2955	373	2	b	b	PROPN
fnp-2955	373	3	,	,	PUNCT
fnp-2955	373	4	carare	carare	PROPN
fnp-2955	373	5	ro	ro	NOUN
fnp-2955	373	6	,	,	PUNCT
fnp-2955	373	7	bechmann	bechmann	PROPN
fnp-2955	373	8	i	i	PRON
fnp-2955	373	9	,	,	PUNCT
fnp-2955	373	10	flugel	flugel	X
fnp-2955	373	11	a	a	PRON
fnp-2955	373	12	,	,	PUNCT
fnp-2955	373	13	laman	laman	PROPN
fnp-2955	373	14	jd	jd	PROPN
fnp-2955	373	15	,	,	PUNCT
fnp-2955	373	16	weller	weller	PROPN
fnp-2955	373	17	ro	ro	NOUN
fnp-2955	373	18	.	.	PROPN
fnp-2955	374	1	vascular	vascular	ADJ
fnp-2955	374	2	,	,	PUNCT
fnp-2955	374	3	glial	glial	ADJ
fnp-2955	374	4	,	,	PUNCT
fnp-2955	374	5	and	and	CCONJ
fnp-2955	374	6	lymphatic	lymphatic	ADJ
fnp-2955	374	7	immune	immune	ADJ
fnp-2955	374	8	gateways	gateway	NOUN
fnp-2955	374	9	of	of	ADP
fnp-2955	374	10	the	the	DET
fnp-2955	374	11	central	central	ADJ
fnp-2955	374	12	nervous	nervous	ADJ
fnp-2955	374	13	system	system	NOUN
fnp-2955	374	14	.	.	PUNCT
fnp-2955	375	1	acta	acta	PROPN
fnp-2955	375	2	neuropathol	neuropathol	PROPN
fnp-2955	375	3	.	.	PUNCT
fnp-2955	376	1	2016;132(3):317	2016;132(3):317	NUM
fnp-2955	376	2	-	-	SYM
fnp-2955	376	3	38	38	NUM
fnp-2955	376	4	.	.	PUNCT
fnp-2955	377	1	copyright	copyright	NOUN
fnp-2955	377	2	:	:	PUNCT
fnp-2955	377	3	©	©	PROPN
fnp-2955	377	4	2020	2020	NUM
fnp-2955	377	5	the	the	DET
fnp-2955	377	6	author(s	author(s	NOUN
fnp-2955	377	7	)	)	PUNCT
fnp-2955	377	8	.	.	PUNCT
fnp-2955	378	1	this	this	PRON
fnp-2955	378	2	is	be	AUX
fnp-2955	378	3	an	an	DET
fnp-2955	378	4	open	open	ADJ
fnp-2955	378	5	access	access	NOUN
fnp-2955	378	6	article	article	NOUN
fnp-2955	378	7	distributed	distribute	VERB
fnp-2955	378	8	under	under	ADP
fnp-2955	378	9	the	the	DET
fnp-2955	378	10	terms	term	NOUN
fnp-2955	378	11	of	of	ADP
fnp-2955	378	12	the	the	DET
fnp-2955	378	13	creative	creative	ADJ
fnp-2955	378	14	commons	common	NOUN
fnp-2955	378	15	attribution	attribution	NOUN
fnp-2955	378	16	4.0	4.0	NUM
fnp-2955	378	17	international	international	ADJ
fnp-2955	378	18	license	license	NOUN
fnp-2955	378	19	(	(	PUNCT
fnp-2955	378	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-2955	378	21	)	)	PUNCT
fnp-2955	378	22	,	,	PUNCT
fnp-2955	378	23	which	which	PRON
fnp-2955	378	24	permits	permit	VERB
fnp-2955	378	25	unrestricted	unrestricted	ADJ
fnp-2955	378	26	use	use	NOUN
fnp-2955	378	27	,	,	PUNCT
fnp-2955	378	28	distribution	distribution	NOUN
fnp-2955	378	29	,	,	PUNCT
fnp-2955	378	30	and	and	CCONJ
fnp-2955	378	31	reproduction	reproduction	NOUN
fnp-2955	378	32	in	in	ADP
fnp-2955	378	33	any	any	DET
fnp-2955	378	34	medium	medium	NOUN
fnp-2955	378	35	,	,	PUNCT
fnp-2955	378	36	provided	provide	VERB
fnp-2955	378	37	the	the	DET
fnp-2955	378	38	original	original	ADJ
fnp-2955	378	39	author	author	NOUN
fnp-2955	378	40	and	and	CCONJ
fnp-2955	378	41	source	source	NOUN
fnp-2955	378	42	are	be	AUX
fnp-2955	378	43	credited	credit	VERB
fnp-2955	378	44	,	,	PUNCT
fnp-2955	378	45	a	a	DET
fnp-2955	378	46	link	link	NOUN
fnp-2955	378	47	to	to	ADP
fnp-2955	378	48	the	the	DET
fnp-2955	378	49	creative	creative	ADJ
fnp-2955	378	50	commons	common	NOUN
fnp-2955	378	51	license	license	NOUN
fnp-2955	378	52	is	be	AUX
fnp-2955	378	53	provided	provide	VERB
fnp-2955	378	54	,	,	PUNCT
fnp-2955	378	55	and	and	CCONJ
fnp-2955	378	56	any	any	DET
fnp-2955	378	57	changes	change	NOUN
fnp-2955	378	58	are	be	AUX
fnp-2955	378	59	indicated	indicate	VERB
fnp-2955	378	60	.	.	PUNCT
fnp-2955	379	1	the	the	DET
fnp-2955	379	2	creative	creative	ADJ
fnp-2955	379	3	commons	common	NOUN
fnp-2955	379	4	public	public	ADJ
fnp-2955	379	5	domain	domain	NOUN
fnp-2955	379	6	dedication	dedication	NOUN
fnp-2955	379	7	waiver	waiver	NOUN
fnp-2955	379	8	(	(	PUNCT
fnp-2955	379	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-2955	379	10	)	)	PUNCT
fnp-2955	379	11	applies	apply	VERB
fnp-2955	379	12	to	to	ADP
fnp-2955	379	13	the	the	DET
fnp-2955	379	14	data	datum	NOUN
fnp-2955	379	15	made	make	VERB
fnp-2955	379	16	available	available	ADJ
fnp-2955	379	17	in	in	ADP
fnp-2955	379	18	this	this	DET
fnp-2955	379	19	article	article	NOUN
fnp-2955	379	20	,	,	PUNCT
fnp-2955	379	21	unless	unless	SCONJ
fnp-2955	379	22	otherwise	otherwise	ADV
fnp-2955	379	23	stated	state	VERB
fnp-2955	379	24	.	.	PUNCT