id	sid	tid	token	lemma	pos
fnp-2971	1	1	loss	loss	NOUN
fnp-2971	1	2	of	of	ADP
fnp-2971	1	3	ramified	ramified	ADJ
fnp-2971	1	4	microglia	microglia	NOUN
fnp-2971	1	5	precedes	precede	VERB
fnp-2971	1	6	axonal	axonal	ADJ
fnp-2971	1	7	spheroid	spheroid	NOUN
fnp-2971	1	8	formation	formation	NOUN
fnp-2971	1	9	in	in	ADP
fnp-2971	1	10	adult	adult	NOUN
fnp-2971	1	11	-	-	PUNCT
fnp-2971	1	12	onset	onset	NOUN
fnp-2971	1	13	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	1	14	with	with	ADP
fnp-2971	1	15	axonal	axonal	ADJ
fnp-2971	1	16	spheroids	spheroid	NOUN
fnp-2971	1	17	.	.	PUNCT
fnp-2971	1	18	feel	feel	VERB
fnp-2971	1	19	free	free	ADJ
fnp-2971	1	20	to	to	PART
fnp-2971	1	21	add	add	VERB
fnp-2971	1	22	comments	comment	NOUN
fnp-2971	1	23	by	by	ADP
fnp-2971	1	24	clicking	click	VERB
fnp-2971	1	25	these	these	DET
fnp-2971	1	26	icons	icon	NOUN
fnp-2971	1	27	on	on	ADP
fnp-2971	1	28	the	the	DET
fnp-2971	1	29	sidebar	sidebar	NOUN
fnp-2971	1	30	free	free	ADJ
fnp-2971	1	31	neuropathology	neuropathology	NOUN
fnp-2971	1	32	1:27	1:27	NUM
fnp-2971	1	33	(	(	PUNCT
fnp-2971	1	34	2020	2020	NUM
fnp-2971	1	35	)	)	PUNCT
fnp-2971	1	36	original	original	ADJ
fnp-2971	1	37	paper	paper	NOUN
fnp-2971	1	38	loss	loss	NOUN
fnp-2971	1	39	of	of	ADP
fnp-2971	1	40	ramified	ramified	ADJ
fnp-2971	1	41	microglia	microglia	NOUN
fnp-2971	1	42	precedes	precede	VERB
fnp-2971	1	43	axonal	axonal	ADJ
fnp-2971	1	44	spheroid	spheroid	NOUN
fnp-2971	1	45	formation	formation	NOUN
fnp-2971	1	46	in	in	ADP
fnp-2971	1	47	adult	adult	NOUN
fnp-2971	1	48	-	-	PUNCT
fnp-2971	1	49	onset	onset	NOUN
fnp-2971	1	50	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	1	51	with	with	ADP
fnp-2971	1	52	axonal	axonal	ADJ
fnp-2971	1	53	spheroids	spheroid	NOUN
fnp-2971	1	54	.	.	PUNCT
fnp-2971	1	55	murad	murad	NOUN
fnp-2971	1	56	alturkustani	alturkustani	PROPN
fnp-2971	1	57	1,2,3	1,2,3	NUM
fnp-2971	1	58	,	,	PUNCT
fnp-2971	1	59	qi	qi	PROPN
fnp-2971	1	60	zhang	zhang	PROPN
fnp-2971	1	61	2,3	2,3	NUM
fnp-2971	1	62	,	,	PUNCT
fnp-2971	1	63	basma	basma	VERB
fnp-2971	1	64	alyamany	alyamany	NOUN
fnp-2971	1	65	2,3	2,3	NUM
fnp-2971	1	66	,	,	PUNCT
fnp-2971	1	67	lee	lee	PROPN
fnp-2971	1	68	-	-	PUNCT
fnp-2971	1	69	cyn	cyn	PROPN
fnp-2971	1	70	ang	ang	NOUN
fnp-2971	1	71	2,3	2,3	NUM
fnp-2971	1	72	1	1	NUM
fnp-2971	1	73	department	department	NOUN
fnp-2971	1	74	of	of	ADP
fnp-2971	1	75	pathology	pathology	PROPN
fnp-2971	1	76	,	,	PUNCT
fnp-2971	1	77	king	king	PROPN
fnp-2971	1	78	abdulaziz	abdulaziz	PROPN
fnp-2971	1	79	university	university	PROPN
fnp-2971	1	80	,	,	PUNCT
fnp-2971	1	81	jeddah	jeddah	PROPN
fnp-2971	1	82	,	,	PUNCT
fnp-2971	1	83	saudi	saudi	PROPN
fnp-2971	1	84	arabia	arabia	PROPN
fnp-2971	1	85	2	2	NUM
fnp-2971	1	86	london	london	PROPN
fnp-2971	1	87	health	health	NOUN
fnp-2971	1	88	sciences	sciences	PROPN
fnp-2971	1	89	centre	centre	PROPN
fnp-2971	1	90	,	,	PUNCT
fnp-2971	1	91	london	london	PROPN
fnp-2971	1	92	,	,	PUNCT
fnp-2971	1	93	ontario	ontario	PROPN
fnp-2971	1	94	,	,	PUNCT
fnp-2971	1	95	canada	canada	PROPN
fnp-2971	1	96	3	3	NUM
fnp-2971	1	97	western	western	PROPN
fnp-2971	1	98	university	university	PROPN
fnp-2971	1	99	,	,	PUNCT
fnp-2971	1	100	london	london	PROPN
fnp-2971	1	101	,	,	PUNCT
fnp-2971	1	102	ontario	ontario	PROPN
fnp-2971	1	103	,	,	PUNCT
fnp-2971	1	104	canada	canada	PROPN
fnp-2971	1	105	corresponding	corresponding	PROPN
fnp-2971	1	106	author	author	NOUN
fnp-2971	1	107	:	:	PUNCT
fnp-2971	1	108	murad	murad	NOUN
fnp-2971	1	109	alturkustani	alturkustani	PROPN
fnp-2971	1	110	·	·	PUNCT
fnp-2971	1	111	pathology	pathology	PROPN
fnp-2971	1	112	department	department	PROPN
fnp-2971	1	113	·	·	PUNCT
fnp-2971	1	114	king	king	PROPN
fnp-2971	1	115	abdulaziz	abdulaziz	PROPN
fnp-2971	1	116	university	university	PROPN
fnp-2971	1	117	·	·	PUNCT
fnp-2971	1	118	abdullah	abdullah	PROPN
fnp-2971	1	119	sulayman	sulayman	PROPN
fnp-2971	1	120	,	,	PUNCT
fnp-2971	1	121	po	po	PROPN
fnp-2971	1	122	box	box	PROPN
fnp-2971	1	123	80205	80205	NUM
fnp-2971	1	124	·	·	PUNCT
fnp-2971	2	1	jeddah	jeddah	PROPN
fnp-2971	2	2	·	·	PUNCT
fnp-2971	2	3	saudi	saudi	PROPN
fnp-2971	2	4	arabia	arabia	PROPN
fnp-2971	2	5	alturkustani.murad@gmail.com	alturkustani.murad@gmail.com	X
fnp-2971	2	6	submitted	submit	VERB
fnp-2971	2	7	:	:	PUNCT
fnp-2971	2	8	22	22	NUM
fnp-2971	2	9	august	august	PROPN
fnp-2971	2	10	2020	2020	NUM
fnp-2971	2	11	accepted	accept	VERB
fnp-2971	2	12	:	:	PUNCT
fnp-2971	2	13	9	9	NUM
fnp-2971	2	14	september	september	PROPN
fnp-2971	2	15	2020	2020	NUM
fnp-2971	2	16	copyedited	copyedit	VERB
fnp-2971	2	17	by	by	ADP
fnp-2971	2	18	:	:	PUNCT
fnp-2971	2	19	deanna	deanna	PROPN
fnp-2971	2	20	c.	c.	PROPN
fnp-2971	2	21	fang	fang	PROPN
fnp-2971	2	22	and	and	CCONJ
fnp-2971	2	23	henry	henry	PROPN
fnp-2971	2	24	robbert	robbert	PROPN
fnp-2971	2	25	published	publish	VERB
fnp-2971	2	26	:	:	PUNCT
fnp-2971	2	27	5	5	NUM
fnp-2971	2	28	october	october	NOUN
fnp-2971	2	29	2020	2020	NUM
fnp-2971	2	30	https://doi.org/10.17879/freeneuropathology-2020-2971	https://doi.org/10.17879/freeneuropathology-2020-2971	VERB
fnp-2971	2	31	additional	additional	ADJ
fnp-2971	2	32	resources	resource	NOUN
fnp-2971	2	33	and	and	CCONJ
fnp-2971	2	34	electronic	electronic	ADJ
fnp-2971	2	35	supplementary	supplementary	ADJ
fnp-2971	2	36	material	material	NOUN
fnp-2971	2	37	:	:	PUNCT
fnp-2971	2	38	supplementary	supplementary	ADJ
fnp-2971	2	39	material	material	NOUN
fnp-2971	2	40	keywords	keyword	NOUN
fnp-2971	2	41	:	:	PUNCT
fnp-2971	2	42	adult	adult	NOUN
fnp-2971	2	43	-	-	PUNCT
fnp-2971	2	44	onset	onset	NOUN
fnp-2971	2	45	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	2	46	with	with	ADP
fnp-2971	2	47	axonal	axonal	ADJ
fnp-2971	2	48	spheroids	spheroid	NOUN
fnp-2971	2	49	,	,	PUNCT
fnp-2971	2	50	leukodystrophy	leukodystrophy	NOUN
fnp-2971	2	51	,	,	PUNCT
fnp-2971	2	52	microglia	microglia	ADJ
fnp-2971	2	53	,	,	PUNCT
fnp-2971	2	54	axonal	axonal	ADJ
fnp-2971	2	55	spheroids	spheroid	NOUN
fnp-2971	2	56	,	,	PUNCT
fnp-2971	2	57	white	white	ADJ
fnp-2971	2	58	matter	matter	NOUN
fnp-2971	2	59	,	,	PUNCT
fnp-2971	2	60	hdls	hdls	PROPN
fnp-2971	2	61	,	,	PUNCT
fnp-2971	2	62	alsp	alsp	PROPN
fnp-2971	2	63	abstract	abstract	ADJ
fnp-2971	2	64	two	two	NUM
fnp-2971	2	65	different	different	ADJ
fnp-2971	2	66	pathological	pathological	ADJ
fnp-2971	2	67	mechanisms	mechanism	NOUN
fnp-2971	2	68	have	have	AUX
fnp-2971	2	69	been	be	AUX
fnp-2971	2	70	suggested	suggest	VERB
fnp-2971	2	71	to	to	PART
fnp-2971	2	72	underlie	underlie	VERB
fnp-2971	2	73	adult	adult	NOUN
fnp-2971	2	74	-	-	PUNCT
fnp-2971	2	75	onset	onset	NOUN
fnp-2971	2	76	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	2	77	with	with	ADP
fnp-2971	2	78	axonal	axonal	ADJ
fnp-2971	2	79	spheroids	spheroid	NOUN
fnp-2971	2	80	(	(	PUNCT
fnp-2971	2	81	alas	alas	INTJ
fnp-2971	2	82	)	)	PUNCT
fnp-2971	2	83	.	.	PUNCT
fnp-2971	3	1	pathological	pathological	ADJ
fnp-2971	3	2	studies	study	NOUN
fnp-2971	3	3	have	have	AUX
fnp-2971	3	4	suggested	suggest	VERB
fnp-2971	3	5	that	that	SCONJ
fnp-2971	3	6	alas	alas	PROPN
fnp-2971	3	7	involves	involve	VERB
fnp-2971	3	8	primary	primary	ADJ
fnp-2971	3	9	axonopathy	axonopathy	NOUN
fnp-2971	3	10	with	with	ADP
fnp-2971	3	11	secondary	secondary	ADJ
fnp-2971	3	12	demyelination	demyelination	NOUN
fnp-2971	3	13	.	.	PUNCT
fnp-2971	4	1	however	however	ADV
fnp-2971	4	2	,	,	PUNCT
fnp-2971	4	3	the	the	DET
fnp-2971	4	4	identification	identification	NOUN
fnp-2971	4	5	of	of	ADP
fnp-2971	4	6	mutations	mutation	NOUN
fnp-2971	4	7	in	in	ADP
fnp-2971	4	8	colony	colony	NOUN
fnp-2971	4	9	stimulating	stimulate	VERB
fnp-2971	4	10	factor	factor	NOUN
fnp-2971	4	11	1	1	NUM
fnp-2971	4	12	receptor	receptor	NOUN
fnp-2971	4	13	(	(	PUNCT
fnp-2971	4	14	csf1r	csf1r	NOUN
fnp-2971	4	15	)	)	PUNCT
fnp-2971	4	16	,	,	PUNCT
fnp-2971	4	17	important	important	ADJ
fnp-2971	4	18	for	for	ADP
fnp-2971	4	19	microglial	microglial	ADJ
fnp-2971	4	20	survival	survival	NOUN
fnp-2971	4	21	,	,	PUNCT
fnp-2971	4	22	has	have	AUX
fnp-2971	4	23	suggested	suggest	VERB
fnp-2971	4	24	that	that	SCONJ
fnp-2971	4	25	alas	alas	PRON
fnp-2971	4	26	is	be	AUX
fnp-2971	4	27	a	a	DET
fnp-2971	4	28	microgliopathy	microgliopathy	NOUN
fnp-2971	4	29	.	.	PUNCT
fnp-2971	5	1	this	this	DET
fnp-2971	5	2	study	study	NOUN
fnp-2971	5	3	examines	examine	VERB
fnp-2971	5	4	the	the	DET
fnp-2971	5	5	correlation	correlation	NOUN
fnp-2971	5	6	between	between	ADP
fnp-2971	5	7	microglial	microglial	ADJ
fnp-2971	5	8	changes	change	NOUN
fnp-2971	5	9	and	and	CCONJ
fnp-2971	5	10	axonopathy	axonopathy	NOUN
fnp-2971	5	11	in	in	ADP
fnp-2971	5	12	alas	alas	INTJ
fnp-2971	5	13	.	.	PUNCT
fnp-2971	6	1	a	a	DET
fnp-2971	6	2	total	total	NOUN
fnp-2971	6	3	of	of	ADP
fnp-2971	6	4	6	6	NUM
fnp-2971	6	5	alas	alas	PRON
fnp-2971	6	6	cases	case	NOUN
fnp-2971	6	7	were	be	AUX
fnp-2971	6	8	studied	study	VERB
fnp-2971	6	9	.	.	PUNCT
fnp-2971	7	1	white	white	ADJ
fnp-2971	7	2	matter	matter	PROPN
fnp-2971	7	3	lesions	lesion	NOUN
fnp-2971	7	4	were	be	AUX
fnp-2971	7	5	classified	classify	VERB
fnp-2971	7	6	into	into	ADP
fnp-2971	7	7	three	three	NUM
fnp-2971	7	8	evolving	evolve	VERB
fnp-2971	7	9	stages	stage	NOUN
fnp-2971	7	10	:	:	PUNCT
fnp-2971	7	11	1	1	X
fnp-2971	7	12	)	)	PUNCT
fnp-2971	7	13	numerous	numerous	ADJ
fnp-2971	7	14	axonal	axonal	ADJ
fnp-2971	7	15	spheroids	spheroid	NOUN
fnp-2971	7	16	among	among	ADP
fnp-2971	7	17	well	well	ADV
fnp-2971	7	18	-	-	PUNCT
fnp-2971	7	19	myelinated	myelinate	VERB
fnp-2971	7	20	fibers	fiber	NOUN
fnp-2971	7	21	;	;	PUNCT
fnp-2971	7	22	2	2	X
fnp-2971	7	23	)	)	PUNCT
fnp-2971	7	24	moderate	moderate	ADJ
fnp-2971	7	25	loss	loss	NOUN
fnp-2971	7	26	of	of	ADP
fnp-2971	7	27	myelinated	myelinated	ADJ
fnp-2971	7	28	fibers	fiber	NOUN
fnp-2971	7	29	with	with	ADP
fnp-2971	7	30	or	or	CCONJ
fnp-2971	7	31	without	without	ADP
fnp-2971	7	32	axonal	axonal	ADJ
fnp-2971	7	33	spheroids	spheroid	NOUN
fnp-2971	7	34	;	;	PUNCT
fnp-2971	7	35	and	and	CCONJ
fnp-2971	7	36	3	3	X
fnp-2971	7	37	)	)	PUNCT
fnp-2971	7	38	a	a	DET
fnp-2971	7	39	leukodystrophy	leukodystrophy	NOUN
fnp-2971	7	40	-	-	PUNCT
fnp-2971	7	41	like	like	ADJ
fnp-2971	7	42	pattern	pattern	NOUN
fnp-2971	7	43	of	of	ADP
fnp-2971	7	44	severe	severe	ADJ
fnp-2971	7	45	confluent	confluent	ADJ
fnp-2971	7	46	axonal	axonal	ADJ
fnp-2971	7	47	and	and	CCONJ
fnp-2971	7	48	myelin	myelin	NOUN
fnp-2971	7	49	loss	loss	NOUN
fnp-2971	7	50	.	.	PUNCT
fnp-2971	8	1	axonal	axonal	ADJ
fnp-2971	8	2	spheroids	spheroid	NOUN
fnp-2971	8	3	and	and	CCONJ
fnp-2971	8	4	ramified	ramify	VERB
fnp-2971	8	5	microglia	microglia	NOUN
fnp-2971	8	6	were	be	AUX
fnp-2971	8	7	semi	semi	ADJ
fnp-2971	8	8	-	-	ADJ
fnp-2971	8	9	quantified	quantified	ADJ
fnp-2971	8	10	and	and	CCONJ
fnp-2971	8	11	the	the	DET
fnp-2971	8	12	lesions	lesion	NOUN
fnp-2971	8	13	were	be	AUX
fnp-2971	8	14	assigned	assign	VERB
fnp-2971	8	15	a	a	DET
fnp-2971	8	16	score	score	NOUN
fnp-2971	8	17	of	of	ADP
fnp-2971	8	18	0–3	0–3	NUM
fnp-2971	8	19	.	.	PUNCT
fnp-2971	9	1	we	we	PRON
fnp-2971	9	2	found	find	VERB
fnp-2971	9	3	a	a	DET
fnp-2971	9	4	strong	strong	ADJ
fnp-2971	9	5	correlation	correlation	NOUN
fnp-2971	9	6	between	between	ADP
fnp-2971	9	7	the	the	DET
fnp-2971	9	8	preponderance	preponderance	NOUN
fnp-2971	9	9	of	of	ADP
fnp-2971	9	10	axonal	axonal	ADJ
fnp-2971	9	11	spheroids	spheroid	NOUN
fnp-2971	9	12	and	and	CCONJ
fnp-2971	9	13	ramified	ramify	VERB
fnp-2971	9	14	microglial	microglial	ADJ
fnp-2971	9	15	loss	loss	NOUN
fnp-2971	9	16	.	.	PUNCT
fnp-2971	10	1	all	all	DET
fnp-2971	10	2	areas	area	NOUN
fnp-2971	10	3	with	with	ADP
fnp-2971	10	4	a	a	DET
fnp-2971	10	5	predominance	predominance	NOUN
fnp-2971	10	6	of	of	ADP
fnp-2971	10	7	axonal	axonal	ADJ
fnp-2971	10	8	spheroids	spheroid	NOUN
fnp-2971	10	9	showed	show	VERB
fnp-2971	10	10	a	a	DET
fnp-2971	10	11	near	near	ADV
fnp-2971	10	12	-	-	PUNCT
fnp-2971	10	13	complete	complete	ADJ
fnp-2971	10	14	absence	absence	NOUN
fnp-2971	10	15	of	of	ADP
fnp-2971	10	16	ramified	ramified	ADJ
fnp-2971	10	17	microglia	microglia	NOUN
fnp-2971	10	18	,	,	PUNCT
fnp-2971	10	19	which	which	PRON
fnp-2971	10	20	was	be	AUX
fnp-2971	10	21	also	also	ADV
fnp-2971	10	22	apparent	apparent	ADJ
fnp-2971	10	23	in	in	ADP
fnp-2971	10	24	small	small	ADJ
fnp-2971	10	25	cortical	cortical	ADJ
fnp-2971	10	26	and	and	CCONJ
fnp-2971	10	27	white	white	ADJ
fnp-2971	10	28	matter	matter	NOUN
fnp-2971	10	29	lesions	lesion	NOUN
fnp-2971	10	30	.	.	PUNCT
fnp-2971	11	1	in	in	ADP
fnp-2971	11	2	contrast	contrast	NOUN
fnp-2971	11	3	,	,	PUNCT
fnp-2971	11	4	some	some	DET
fnp-2971	11	5	areas	area	NOUN
fnp-2971	11	6	with	with	ADP
fnp-2971	11	7	no	no	DET
fnp-2971	11	8	ramified	ramified	ADJ
fnp-2971	11	9	microglia	microglia	NOUN
fnp-2971	11	10	showed	show	VERB
fnp-2971	11	11	no	no	DET
fnp-2971	11	12	axonal	axonal	ADJ
fnp-2971	11	13	pathology	pathology	NOUN
fnp-2971	11	14	.	.	PUNCT
fnp-2971	12	1	our	our	PRON
fnp-2971	12	2	findings	finding	NOUN
fnp-2971	12	3	support	support	VERB
fnp-2971	12	4	the	the	DET
fnp-2971	12	5	suggestion	suggestion	NOUN
fnp-2971	12	6	that	that	SCONJ
fnp-2971	12	7	ramified	ramify	VERB
fnp-2971	12	8	microglia	microglia	ADJ
fnp-2971	12	9	loss	loss	NOUN
fnp-2971	12	10	precedes	precede	VERB
fnp-2971	12	11	axonal	axonal	ADJ
fnp-2971	12	12	spheroids	spheroid	NOUN
fnp-2971	12	13	formation	formation	NOUN
fnp-2971	12	14	.	.	PUNCT
fnp-2971	13	1	this	this	DET
fnp-2971	13	2	observation	observation	NOUN
fnp-2971	13	3	will	will	AUX
fnp-2971	13	4	help	help	VERB
fnp-2971	13	5	to	to	PART
fnp-2971	13	6	better	well	ADV
fnp-2971	13	7	understand	understand	VERB
fnp-2971	13	8	the	the	DET
fnp-2971	13	9	pathogenesis	pathogenesis	NOUN
fnp-2971	13	10	of	of	ADP
fnp-2971	13	11	alas	alas	PRON
fnp-2971	13	12	and	and	CCONJ
fnp-2971	13	13	suggests	suggest	VERB
fnp-2971	13	14	a	a	DET
fnp-2971	13	15	protective	protective	ADJ
fnp-2971	13	16	role	role	NOUN
fnp-2971	13	17	of	of	ADP
fnp-2971	13	18	microglia	microglia	NOUN
fnp-2971	13	19	.	.	PUNCT
fnp-2971	14	1	introduction	introduction	NOUN
fnp-2971	14	2	two	two	NUM
fnp-2971	14	3	different	different	ADJ
fnp-2971	14	4	pathological	pathological	ADJ
fnp-2971	14	5	mechanisms	mechanism	NOUN
fnp-2971	14	6	have	have	AUX
fnp-2971	14	7	been	be	AUX
fnp-2971	14	8	suggested	suggest	VERB
fnp-2971	14	9	to	to	PART
fnp-2971	14	10	underlie	underlie	VERB
fnp-2971	14	11	adult	adult	NOUN
fnp-2971	14	12	-	-	PUNCT
fnp-2971	14	13	onset	onset	NOUN
fnp-2971	14	14	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	14	15	with	with	ADP
fnp-2971	14	16	axonal	axonal	ADJ
fnp-2971	14	17	spheroids	spheroid	NOUN
fnp-2971	14	18	(	(	PUNCT
fnp-2971	14	19	alas	alas	INTJ
fnp-2971	14	20	)	)	PUNCT
fnp-2971	14	21	.	.	PUNCT
fnp-2971	15	1	pathological	pathological	ADJ
fnp-2971	15	2	studies	study	NOUN
fnp-2971	15	3	have	have	AUX
fnp-2971	15	4	proposed	propose	VERB
fnp-2971	15	5	a	a	DET
fnp-2971	15	6	primary	primary	ADJ
fnp-2971	15	7	axonopathy	axonopathy	NOUN
fnp-2971	15	8	with	with	ADP
fnp-2971	15	9	secondary	secondary	ADJ
fnp-2971	15	10	demyelination	demyelination	NOUN
fnp-2971	15	11	(	(	PUNCT
fnp-2971	15	12	1	1	NUM
fnp-2971	15	13	,	,	PUNCT
fnp-2971	15	14	2	2	NUM
fnp-2971	15	15	)	)	PUNCT
fnp-2971	15	16	,	,	PUNCT
fnp-2971	15	17	while	while	SCONJ
fnp-2971	15	18	genetic	genetic	ADJ
fnp-2971	15	19	/	/	SYM
fnp-2971	15	20	molecular	molecular	ADJ
fnp-2971	15	21	studies	study	NOUN
fnp-2971	15	22	have	have	AUX
fnp-2971	15	23	identified	identify	VERB
fnp-2971	15	24	a	a	DET
fnp-2971	15	25	mutation	mutation	NOUN
fnp-2971	15	26	in	in	ADP
fnp-2971	15	27	a	a	DET
fnp-2971	15	28	gene	gene	NOUN
fnp-2971	15	29	important	important	ADJ
fnp-2971	15	30	for	for	ADP
fnp-2971	15	31	microglial	microglial	ADJ
fnp-2971	15	32	function	function	NOUN
fnp-2971	15	33	and	and	CCONJ
fnp-2971	15	34	,	,	PUNCT
fnp-2971	15	35	hence	hence	ADV
fnp-2971	15	36	,	,	PUNCT
fnp-2971	15	37	implied	imply	VERB
fnp-2971	15	38	that	that	SCONJ
fnp-2971	15	39	alas	alas	PRON
fnp-2971	15	40	is	be	AUX
fnp-2971	15	41	a	a	DET
fnp-2971	15	42	microgliopathy	microgliopathy	ADJ
fnp-2971	15	43	(	(	PUNCT
fnp-2971	15	44	3	3	NUM
fnp-2971	15	45	)	)	PUNCT
fnp-2971	15	46	.	.	PUNCT
fnp-2971	16	1	moreover	moreover	ADV
fnp-2971	16	2	,	,	PUNCT
fnp-2971	16	3	a	a	DET
fnp-2971	16	4	recent	recent	ADJ
fnp-2971	16	5	pathological	pathological	ADJ
fnp-2971	16	6	study	study	NOUN
fnp-2971	16	7	has	have	AUX
fnp-2971	16	8	identified	identify	VERB
fnp-2971	16	9	a	a	DET
fnp-2971	16	10	microglial	microglial	ADJ
fnp-2971	16	11	morphological	morphological	ADJ
fnp-2971	16	12	alteration	alteration	NOUN
fnp-2971	16	13	(	(	PUNCT
fnp-2971	16	14	i.e.	i.e.	X
fnp-2971	16	15	“	"	PUNCT
fnp-2971	16	16	dysplastic	dysplastic	ADJ
fnp-2971	16	17	”	"	PUNCT
fnp-2971	16	18	microglia	microglia	NOUN
fnp-2971	16	19	)	)	PUNCT
fnp-2971	16	20	as	as	ADP
fnp-2971	16	21	the	the	DET
fnp-2971	16	22	pathological	pathological	ADJ
fnp-2971	16	23	correlate	correlate	NOUN
fnp-2971	16	24	for	for	ADP
fnp-2971	16	25	microgliopathy	microgliopathy	ADJ
fnp-2971	16	26	(	(	PUNCT
fnp-2971	16	27	4	4	NUM
fnp-2971	16	28	)	)	PUNCT
fnp-2971	16	29	.	.	PUNCT
fnp-2971	17	1	alas	ala	NOUN
fnp-2971	17	2	is	be	AUX
fnp-2971	17	3	also	also	ADV
fnp-2971	17	4	known	know	VERB
fnp-2971	17	5	by	by	ADP
fnp-2971	17	6	other	other	ADJ
fnp-2971	17	7	names	name	NOUN
fnp-2971	17	8	in	in	ADP
fnp-2971	17	9	the	the	DET
fnp-2971	17	10	literature	literature	NOUN
fnp-2971	17	11	with	with	ADP
fnp-2971	17	12	most	most	ADJ
fnp-2971	17	13	common	common	ADJ
fnp-2971	17	14	ones	one	NOUN
fnp-2971	17	15	being	be	AUX
fnp-2971	17	16	hereditary	hereditary	ADJ
fnp-2971	17	17	diffuse	diffuse	NOUN
fnp-2971	17	18	leukoencephalopathy	leukoencephalopathy	ADJ
fnp-2971	17	19	with	with	ADP
fnp-2971	17	20	spheroids	spheroid	NOUN
fnp-2971	17	21	(	(	PUNCT
fnp-2971	17	22	hdls	hdls	X
fnp-2971	17	23	)	)	PUNCT
fnp-2971	17	24	and	and	CCONJ
fnp-2971	17	25	adult	adult	NOUN
fnp-2971	17	26	-	-	PUNCT
fnp-2971	17	27	onset	onset	NOUN
fnp-2971	17	28	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	17	29	with	with	ADP
fnp-2971	17	30	axonal	axonal	ADJ
fnp-2971	17	31	spheroids	spheroid	NOUN
fnp-2971	17	32	and	and	CCONJ
fnp-2971	17	33	pigmented	pigmented	ADJ
fnp-2971	17	34	glia	glia	NOUN
fnp-2971	17	35	(	(	PUNCT
fnp-2971	17	36	alsp	alsp	PROPN
fnp-2971	17	37	)	)	PUNCT
fnp-2971	17	38	.	.	PUNCT
fnp-2971	18	1	recent	recent	ADJ
fnp-2971	18	2	advances	advance	NOUN
fnp-2971	18	3	in	in	ADP
fnp-2971	18	4	our	our	PRON
fnp-2971	18	5	understanding	understanding	NOUN
fnp-2971	18	6	of	of	ADP
fnp-2971	18	7	the	the	DET
fnp-2971	18	8	biology	biology	NOUN
fnp-2971	18	9	and	and	CCONJ
fnp-2971	18	10	functions	function	NOUN
fnp-2971	18	11	of	of	ADP
fnp-2971	18	12	microglia	microglia	NOUN
fnp-2971	18	13	have	have	AUX
fnp-2971	18	14	demonstrated	demonstrate	VERB
fnp-2971	18	15	both	both	DET
fnp-2971	18	16	its	its	PRON
fnp-2971	18	17	beneficial	beneficial	ADJ
fnp-2971	18	18	and	and	CCONJ
fnp-2971	18	19	harmful	harmful	ADJ
fnp-2971	18	20	effects	effect	NOUN
fnp-2971	18	21	on	on	ADP
fnp-2971	18	22	various	various	ADJ
fnp-2971	18	23	diseases	disease	NOUN
fnp-2971	18	24	(	(	PUNCT
fnp-2971	18	25	5	5	NUM
fnp-2971	18	26	)	)	PUNCT
fnp-2971	18	27	.	.	PUNCT
fnp-2971	19	1	investigating	investigate	VERB
fnp-2971	19	2	the	the	DET
fnp-2971	19	3	relationship	relationship	NOUN
fnp-2971	19	4	between	between	ADP
fnp-2971	19	5	microgliopathy	microgliopathy	NOUN
fnp-2971	19	6	and	and	CCONJ
fnp-2971	19	7	axonopathy	axonopathy	NOUN
fnp-2971	19	8	in	in	ADP
fnp-2971	19	9	the	the	DET
fnp-2971	19	10	pathogenesis	pathogenesis	NOUN
fnp-2971	19	11	of	of	ADP
fnp-2971	19	12	alas	alas	PRON
fnp-2971	19	13	may	may	AUX
fnp-2971	19	14	provide	provide	VERB
fnp-2971	19	15	better	well	ADJ
fnp-2971	19	16	insight	insight	NOUN
fnp-2971	19	17	into	into	ADP
fnp-2971	19	18	the	the	DET
fnp-2971	19	19	role	role	NOUN
fnp-2971	19	20	of	of	ADP
fnp-2971	19	21	microglia	microglia	NOUN
fnp-2971	19	22	in	in	ADP
fnp-2971	19	23	this	this	DET
fnp-2971	19	24	disease	disease	NOUN
fnp-2971	19	25	.	.	PUNCT
fnp-2971	20	1	recent	recent	ADJ
fnp-2971	20	2	attempts	attempt	NOUN
fnp-2971	20	3	to	to	PART
fnp-2971	20	4	explain	explain	VERB
fnp-2971	20	5	the	the	DET
fnp-2971	20	6	pathogenesis	pathogenesis	NOUN
fnp-2971	20	7	yielded	yield	VERB
fnp-2971	20	8	different	different	ADJ
fnp-2971	20	9	conclusions	conclusion	NOUN
fnp-2971	20	10	:	:	PUNCT
fnp-2971	20	11	1	1	NUM
fnp-2971	20	12	)	)	PUNCT
fnp-2971	20	13	generalized	generalized	ADJ
fnp-2971	20	14	colony	colony	NOUN
fnp-2971	20	15	stimulating	stimulate	VERB
fnp-2971	20	16	factor	factor	NOUN
fnp-2971	20	17	1	1	NUM
fnp-2971	20	18	receptor	receptor	NOUN
fnp-2971	20	19	(	(	PUNCT
fnp-2971	20	20	csf1r	csf1r	NOUN
fnp-2971	20	21	)	)	PUNCT
fnp-2971	20	22	signaling	signal	VERB
fnp-2971	20	23	impairment	impairment	NOUN
fnp-2971	20	24	in	in	ADP
fnp-2971	20	25	cd68	cd68	PROPN
fnp-2971	20	26	-	-	PUNCT
fnp-2971	20	27	immunopositive	immunopositive	ADJ
fnp-2971	20	28	microglia	microglia	NOUN
fnp-2971	20	29	is	be	AUX
fnp-2971	20	30	followed	follow	VERB
fnp-2971	20	31	by	by	ADP
fnp-2971	20	32	multifocal	multifocal	ADJ
fnp-2971	20	33	axonal	axonal	ADJ
fnp-2971	20	34	degeneration	degeneration	NOUN
fnp-2971	20	35	(	(	PUNCT
fnp-2971	20	36	6	6	NUM
fnp-2971	20	37	)	)	PUNCT
fnp-2971	20	38	;	;	PUNCT
fnp-2971	20	39	2	2	X
fnp-2971	20	40	)	)	PUNCT
fnp-2971	20	41	increase	increase	NOUN
fnp-2971	20	42	in	in	ADP
fnp-2971	20	43	ionizing	ionize	VERB
fnp-2971	20	44	calcium	calcium	NOUN
fnp-2971	20	45	-	-	PUNCT
fnp-2971	20	46	binding	bind	VERB
fnp-2971	20	47	molecule	molecule	NOUN
fnp-2971	20	48	1	1	NUM
fnp-2971	20	49	(	(	PUNCT
fnp-2971	20	50	iba1	iba1	PROPN
fnp-2971	20	51	)	)	PUNCT
fnp-2971	20	52	and	and	CCONJ
fnp-2971	20	53	cd68	cd68	PROPN
fnp-2971	20	54	-	-	PUNCT
fnp-2971	20	55	immunopositive	immunopositive	ADJ
fnp-2971	20	56	cell	cell	NOUN
fnp-2971	20	57	numbers	number	NOUN
fnp-2971	20	58	precedes	precede	VERB
fnp-2971	20	59	axonal	axonal	ADJ
fnp-2971	20	60	pathology	pathology	NOUN
fnp-2971	20	61	(	(	PUNCT
fnp-2971	20	62	7	7	NUM
fnp-2971	20	63	)	)	PUNCT
fnp-2971	20	64	;	;	PUNCT
fnp-2971	20	65	3	3	X
fnp-2971	20	66	)	)	PUNCT
fnp-2971	20	67	uneven	uneven	ADJ
fnp-2971	20	68	distribution	distribution	NOUN
fnp-2971	20	69	of	of	ADP
fnp-2971	20	70	iba1	iba1	PROPN
fnp-2971	20	71	-	-	PUNCT
fnp-2971	20	72	immunopositive	immunopositive	ADJ
fnp-2971	20	73	cells	cell	NOUN
fnp-2971	20	74	in	in	ADP
fnp-2971	20	75	the	the	DET
fnp-2971	20	76	white	white	ADJ
fnp-2971	20	77	matter	matter	NOUN
fnp-2971	20	78	precludes	preclude	VERB
fnp-2971	20	79	any	any	DET
fnp-2971	20	80	firm	firm	ADJ
fnp-2971	20	81	conclusions	conclusion	NOUN
fnp-2971	20	82	regarding	regard	VERB
fnp-2971	20	83	the	the	DET
fnp-2971	20	84	role	role	NOUN
fnp-2971	20	85	of	of	ADP
fnp-2971	20	86	these	these	DET
fnp-2971	20	87	cells	cell	NOUN
fnp-2971	20	88	in	in	ADP
fnp-2971	20	89	the	the	DET
fnp-2971	20	90	pathology	pathology	NOUN
fnp-2971	20	91	(	(	PUNCT
fnp-2971	20	92	4	4	NUM
fnp-2971	20	93	)	)	PUNCT
fnp-2971	20	94	;	;	PUNCT
fnp-2971	20	95	and	and	CCONJ
fnp-2971	20	96	4	4	X
fnp-2971	20	97	)	)	PUNCT
fnp-2971	20	98	csf1r	csf1r	PROPN
fnp-2971	20	99	mutations	mutation	NOUN
fnp-2971	20	100	lead	lead	VERB
fnp-2971	20	101	to	to	ADP
fnp-2971	20	102	aberrant	aberrant	ADJ
fnp-2971	20	103	microglia	microglia	ADJ
fnp-2971	20	104	density	density	NOUN
fnp-2971	20	105	and	and	CCONJ
fnp-2971	20	106	distribution	distribution	NOUN
fnp-2971	20	107	,	,	PUNCT
fnp-2971	20	108	and	and	CCONJ
fnp-2971	20	109	regional	regional	ADJ
fnp-2971	20	110	loss	loss	NOUN
fnp-2971	20	111	of	of	ADP
fnp-2971	20	112	microglia	microglia	NOUN
fnp-2971	20	113	(	(	PUNCT
fnp-2971	20	114	8)	8)	NUM
fnp-2971	20	115	.	.	PUNCT
fnp-2971	21	1	in	in	ADP
fnp-2971	21	2	this	this	DET
fnp-2971	21	3	study	study	NOUN
fnp-2971	21	4	,	,	PUNCT
fnp-2971	21	5	we	we	PRON
fnp-2971	21	6	investigated	investigate	VERB
fnp-2971	21	7	the	the	DET
fnp-2971	21	8	relationship	relationship	NOUN
fnp-2971	21	9	between	between	ADP
fnp-2971	21	10	axonal	axonal	ADJ
fnp-2971	21	11	pathology	pathology	NOUN
fnp-2971	21	12	and	and	CCONJ
fnp-2971	21	13	microglial	microglial	ADJ
fnp-2971	21	14	changes	change	NOUN
fnp-2971	21	15	in	in	ADP
fnp-2971	21	16	alas	ala	NOUN
fnp-2971	21	17	using	use	VERB
fnp-2971	21	18	the	the	DET
fnp-2971	21	19	pathological	pathological	ADJ
fnp-2971	21	20	staging	staging	NOUN
fnp-2971	21	21	system	system	NOUN
fnp-2971	21	22	of	of	ADP
fnp-2971	21	23	alas	alas	PRON
fnp-2971	21	24	proposed	propose	VERB
fnp-2971	21	25	by	by	ADP
fnp-2971	21	26	alturkustani	alturkustani	PROPN
fnp-2971	21	27	et	et	PROPN
fnp-2971	21	28	al	al	PROPN
fnp-2971	21	29	.	.	PROPN
fnp-2971	22	1	(	(	PUNCT
fnp-2971	22	2	1	1	NUM
fnp-2971	22	3	)	)	PUNCT
fnp-2971	22	4	.	.	PUNCT
fnp-2971	23	1	this	this	DET
fnp-2971	23	2	system	system	NOUN
fnp-2971	23	3	focuses	focus	VERB
fnp-2971	23	4	on	on	ADP
fnp-2971	23	5	the	the	DET
fnp-2971	23	6	specific	specific	ADJ
fnp-2971	23	7	stages	stage	NOUN
fnp-2971	23	8	of	of	ADP
fnp-2971	23	9	the	the	DET
fnp-2971	23	10	lesions	lesion	NOUN
fnp-2971	23	11	rather	rather	ADV
fnp-2971	23	12	than	than	ADP
fnp-2971	23	13	the	the	DET
fnp-2971	23	14	overall	overall	ADJ
fnp-2971	23	15	pathological	pathological	ADJ
fnp-2971	23	16	stage	stage	NOUN
fnp-2971	23	17	of	of	ADP
fnp-2971	23	18	the	the	DET
fnp-2971	23	19	entire	entire	ADJ
fnp-2971	23	20	case	case	NOUN
fnp-2971	23	21	at	at	ADP
fnp-2971	23	22	a	a	DET
fnp-2971	23	23	point	point	NOUN
fnp-2971	23	24	in	in	ADP
fnp-2971	23	25	time	time	NOUN
fnp-2971	23	26	(	(	PUNCT
fnp-2971	23	27	7	7	NUM
fnp-2971	23	28	)	)	PUNCT
fnp-2971	23	29	and	and	CCONJ
fnp-2971	23	30	should	should	AUX
fnp-2971	23	31	provide	provide	VERB
fnp-2971	23	32	a	a	DET
fnp-2971	23	33	more	more	ADV
fnp-2971	23	34	precise	precise	ADJ
fnp-2971	23	35	correlation	correlation	NOUN
fnp-2971	23	36	.	.	PUNCT
fnp-2971	24	1	materials	material	NOUN
fnp-2971	24	2	and	and	CCONJ
fnp-2971	24	3	methods	method	NOUN
fnp-2971	24	4	a	a	DET
fnp-2971	24	5	formal	formal	ADJ
fnp-2971	24	6	autopsy	autopsy	ADJ
fnp-2971	24	7	consent	consent	NOUN
fnp-2971	24	8	was	be	AUX
fnp-2971	24	9	provided	provide	VERB
fnp-2971	24	10	in	in	ADP
fnp-2971	24	11	all	all	DET
fnp-2971	24	12	cases	case	NOUN
fnp-2971	24	13	and	and	CCONJ
fnp-2971	24	14	the	the	DET
fnp-2971	24	15	western	western	ADJ
fnp-2971	24	16	university	university	PROPN
fnp-2971	24	17	research	research	NOUN
fnp-2971	24	18	ethics	ethic	NOUN
fnp-2971	24	19	board	board	PROPN
fnp-2971	24	20	approved	approve	VERB
fnp-2971	24	21	the	the	DET
fnp-2971	24	22	study	study	NOUN
fnp-2971	24	23	.	.	PUNCT
fnp-2971	25	1	a	a	DET
fnp-2971	25	2	total	total	NOUN
fnp-2971	25	3	of	of	ADP
fnp-2971	25	4	6	6	NUM
fnp-2971	25	5	alas	alas	PRON
fnp-2971	25	6	cases	case	NOUN
fnp-2971	25	7	were	be	AUX
fnp-2971	25	8	studied	study	VERB
fnp-2971	25	9	.	.	PUNCT
fnp-2971	26	1	four	four	NUM
fnp-2971	26	2	cases	case	NOUN
fnp-2971	26	3	were	be	AUX
fnp-2971	26	4	described	describe	VERB
fnp-2971	26	5	before	before	ADV
fnp-2971	26	6	(	(	PUNCT
fnp-2971	26	7	cases	case	NOUN
fnp-2971	26	8	1–4	1–4	NUM
fnp-2971	26	9	)	)	PUNCT
fnp-2971	26	10	(	(	PUNCT
fnp-2971	26	11	1	1	NUM
fnp-2971	26	12	)	)	PUNCT
fnp-2971	26	13	.	.	PUNCT
fnp-2971	27	1	two	two	NUM
fnp-2971	27	2	additional	additional	ADJ
fnp-2971	27	3	cases	case	NOUN
fnp-2971	27	4	of	of	ADP
fnp-2971	27	5	alas	ala	NOUN
fnp-2971	27	6	were	be	AUX
fnp-2971	27	7	referred	refer	VERB
fnp-2971	27	8	to	to	ADP
fnp-2971	27	9	the	the	DET
fnp-2971	27	10	london	london	PROPN
fnp-2971	27	11	health	health	PROPN
fnp-2971	27	12	sciences	sciences	PROPN
fnp-2971	27	13	center	center	PROPN
fnp-2971	27	14	laboratory	laboratory	NOUN
fnp-2971	27	15	in	in	ADP
fnp-2971	27	16	2013–2017	2013–2017	NUM
fnp-2971	27	17	.	.	PUNCT
fnp-2971	28	1	the	the	DET
fnp-2971	28	2	brains	brain	NOUN
fnp-2971	28	3	were	be	AUX
fnp-2971	28	4	fixed	fix	VERB
fnp-2971	28	5	and	and	CCONJ
fnp-2971	28	6	prepared	prepare	VERB
fnp-2971	28	7	as	as	SCONJ
fnp-2971	28	8	described	describe	VERB
fnp-2971	28	9	before	before	ADV
fnp-2971	28	10	(	(	PUNCT
fnp-2971	28	11	1	1	NUM
fnp-2971	28	12	)	)	PUNCT
fnp-2971	28	13	.	.	PUNCT
fnp-2971	29	1	representative	representative	ADJ
fnp-2971	29	2	samples	sample	NOUN
fnp-2971	29	3	were	be	AUX
fnp-2971	29	4	submitted	submit	VERB
fnp-2971	29	5	for	for	ADP
fnp-2971	29	6	microscopic	microscopic	ADJ
fnp-2971	29	7	examination	examination	NOUN
fnp-2971	29	8	and	and	CCONJ
fnp-2971	29	9	staining	stain	VERB
fnp-2971	29	10	,	,	PUNCT
fnp-2971	29	11	and	and	CCONJ
fnp-2971	29	12	immunostaining	immunostaining	NOUN
fnp-2971	29	13	procedures	procedure	NOUN
fnp-2971	29	14	were	be	AUX
fnp-2971	29	15	performed	perform	VERB
fnp-2971	29	16	as	as	SCONJ
fnp-2971	29	17	described	describe	VERB
fnp-2971	29	18	previously	previously	ADV
fnp-2971	29	19	(	(	PUNCT
fnp-2971	29	20	1	1	NUM
fnp-2971	29	21	)	)	PUNCT
fnp-2971	29	22	.	.	PUNCT
fnp-2971	30	1	these	these	DET
fnp-2971	30	2	procedures	procedure	NOUN
fnp-2971	30	3	include	include	VERB
fnp-2971	30	4	luxol	luxol	NOUN
fnp-2971	30	5	fast	fast	PROPN
fnp-2971	30	6	blue	blue	ADJ
fnp-2971	30	7	(	(	PUNCT
fnp-2971	30	8	lfb	lfb	PROPN
fnp-2971	30	9	)	)	PUNCT
fnp-2971	30	10	with	with	ADP
fnp-2971	30	11	hematoxylin	hematoxylin	NOUN
fnp-2971	30	12	and	and	CCONJ
fnp-2971	30	13	eosin	eosin	NOUN
fnp-2971	30	14	(	(	PUNCT
fnp-2971	30	15	he	he	PRON
fnp-2971	30	16	)	)	PUNCT
fnp-2971	30	17	staining	stain	VERB
fnp-2971	30	18	.	.	PUNCT
fnp-2971	31	1	for	for	ADP
fnp-2971	31	2	immunohistochemistry	immunohistochemistry	NOUN
fnp-2971	31	3	,	,	PUNCT
fnp-2971	31	4	the	the	DET
fnp-2971	31	5	primary	primary	ADJ
fnp-2971	31	6	antibodies	antibody	NOUN
fnp-2971	31	7	used	use	VERB
fnp-2971	31	8	were	be	AUX
fnp-2971	31	9	anti	anti	ADJ
fnp-2971	31	10	-	-	ADJ
fnp-2971	31	11	amyloid	amyloid	ADJ
fnp-2971	31	12	precursor	precursor	NOUN
fnp-2971	31	13	protein	protein	NOUN
fnp-2971	31	14	(	(	PUNCT
fnp-2971	31	15	app	app	X
fnp-2971	31	16	;	;	PUNCT
fnp-2971	31	17	chemicon	chemicon	NOUN
fnp-2971	31	18	,	,	PUNCT
fnp-2971	31	19	temecula	temecula	PROPN
fnp-2971	31	20	,	,	PUNCT
fnp-2971	31	21	ca	ca	NOUN
fnp-2971	31	22	)	)	PUNCT
fnp-2971	31	23	,	,	PUNCT
fnp-2971	31	24	anti	anti	ADJ
fnp-2971	31	25	-	-	ADJ
fnp-2971	31	26	phosphorylated	phosphorylated	ADJ
fnp-2971	31	27	neurofilament	neurofilament	NOUN
fnp-2971	31	28	(	(	PUNCT
fnp-2971	31	29	smi31	smi31	NOUN
fnp-2971	31	30	;	;	PUNCT
fnp-2971	31	31	covance	covance	NOUN
fnp-2971	31	32	,	,	PUNCT
fnp-2971	31	33	berkeley	berkeley	PROPN
fnp-2971	31	34	,	,	PUNCT
fnp-2971	31	35	ca	ca	NOUN
fnp-2971	31	36	)	)	PUNCT
fnp-2971	31	37	,	,	PUNCT
fnp-2971	31	38	and	and	CCONJ
fnp-2971	31	39	anti	anti	ADJ
fnp-2971	31	40	-	-	ADJ
fnp-2971	31	41	glial	glial	ADJ
fnp-2971	31	42	fibrillary	fibrillary	ADJ
fnp-2971	31	43	acidic	acidic	ADJ
fnp-2971	31	44	protein	protein	NOUN
fnp-2971	31	45	(	(	PUNCT
fnp-2971	31	46	dako	dako	PROPN
fnp-2971	31	47	,	,	PUNCT
fnp-2971	31	48	carpinteria	carpinteria	PROPN
fnp-2971	31	49	,	,	PUNCT
fnp-2971	31	50	ca	ca	NOUN
fnp-2971	31	51	)	)	PUNCT
fnp-2971	31	52	.	.	PUNCT
fnp-2971	32	1	mouse	mouse	NOUN
fnp-2971	32	2	monoclonal	monoclonal	ADJ
fnp-2971	32	3	anti	anti	ADJ
fnp-2971	32	4	-	-	ADJ
fnp-2971	32	5	hla	hla	ADJ
fnp-2971	32	6	-	-	PUNCT
fnp-2971	32	7	dr	dr	NOUN
fnp-2971	32	8	antibody	antibody	NOUN
fnp-2971	32	9	(	(	PUNCT
fnp-2971	32	10	1:200	1:200	NUM
fnp-2971	32	11	;	;	PUNCT
fnp-2971	32	12	clone	clone	NOUN
fnp-2971	32	13	cr3/43	cr3/43	NOUN
fnp-2971	32	14	;	;	PUNCT
fnp-2971	32	15	dako	dako	PROPN
fnp-2971	32	16	,	,	PUNCT
fnp-2971	32	17	carpinteria	carpinteria	PROPN
fnp-2971	32	18	,	,	PUNCT
fnp-2971	32	19	ca	ca	NOUN
fnp-2971	32	20	)	)	PUNCT
fnp-2971	32	21	was	be	AUX
fnp-2971	32	22	used	use	VERB
fnp-2971	32	23	to	to	PART
fnp-2971	32	24	label	label	VERB
fnp-2971	32	25	microglial	microglial	ADJ
fnp-2971	32	26	cells	cell	NOUN
fnp-2971	32	27	.	.	PUNCT
fnp-2971	33	1	anti	anti	ADJ
fnp-2971	33	2	-	-	ADJ
fnp-2971	33	3	ionized	ionized	ADJ
fnp-2971	33	4	calcium	calcium	NOUN
fnp-2971	33	5	binding	bind	VERB
fnp-2971	33	6	adaptor	adaptor	NOUN
fnp-2971	33	7	molecule	molecule	NOUN
fnp-2971	33	8	1	1	NUM
fnp-2971	33	9	(	(	PUNCT
fnp-2971	33	10	iba1	iba1	PROPN
fnp-2971	33	11	)	)	PUNCT
fnp-2971	33	12	antibody	antibody	NOUN
fnp-2971	33	13	(	(	PUNCT
fnp-2971	33	14	1:500	1:500	NUM
fnp-2971	33	15	,	,	PUNCT
fnp-2971	33	16	019	019	NUM
fnp-2971	33	17	-	-	SYM
fnp-2971	33	18	19741	19741	NUM
fnp-2971	33	19	,	,	PUNCT
fnp-2971	33	20	wako	wako	PROPN
fnp-2971	33	21	)	)	PUNCT
fnp-2971	33	22	was	be	AUX
fnp-2971	33	23	stained	stain	VERB
fnp-2971	33	24	in	in	ADP
fnp-2971	33	25	dr	dr	PROPN
fnp-2971	33	26	.	.	PROPN
fnp-2971	34	1	v.	v.	PROPN
fnp-2971	34	2	wee	wee	PROPN
fnp-2971	34	3	yong	yong	PROPN
fnp-2971	34	4	’s	’s	PROPN
fnp-2971	34	5	laboratory	laboratory	PROPN
fnp-2971	34	6	(	(	PUNCT
fnp-2971	34	7	calgary	calgary	PROPN
fnp-2971	34	8	,	,	PUNCT
fnp-2971	34	9	canada	canada	PROPN
fnp-2971	34	10	)	)	PUNCT
fnp-2971	35	1	following	follow	VERB
fnp-2971	35	2	their	their	PRON
fnp-2971	35	3	previously	previously	ADV
fnp-2971	35	4	published	publish	VERB
fnp-2971	35	5	protocol	protocol	NOUN
fnp-2971	35	6	(	(	PUNCT
fnp-2971	35	7	9	9	NUM
fnp-2971	35	8	)	)	PUNCT
fnp-2971	35	9	.	.	PUNCT
fnp-2971	36	1	the	the	DET
fnp-2971	36	2	white	white	ADJ
fnp-2971	36	3	matter	matter	NOUN
fnp-2971	36	4	lesions	lesion	NOUN
fnp-2971	36	5	were	be	AUX
fnp-2971	36	6	classified	classify	VERB
fnp-2971	36	7	into	into	ADP
fnp-2971	36	8	three	three	NUM
fnp-2971	36	9	evolving	evolve	VERB
fnp-2971	36	10	stages	stage	NOUN
fnp-2971	36	11	,	,	PUNCT
fnp-2971	36	12	as	as	SCONJ
fnp-2971	36	13	discussed	discuss	VERB
fnp-2971	36	14	in	in	ADP
fnp-2971	36	15	our	our	PRON
fnp-2971	36	16	previous	previous	ADJ
fnp-2971	36	17	work	work	NOUN
fnp-2971	36	18	(	(	PUNCT
fnp-2971	36	19	1	1	NUM
fnp-2971	36	20	):	):	SYM
fnp-2971	36	21	1	1	NUM
fnp-2971	36	22	)	)	PUNCT
fnp-2971	36	23	numerous	numerous	ADJ
fnp-2971	36	24	axonal	axonal	ADJ
fnp-2971	36	25	spheroids	spheroid	NOUN
fnp-2971	36	26	within	within	ADP
fnp-2971	36	27	well	well	ADV
fnp-2971	36	28	-	-	PUNCT
fnp-2971	36	29	myelinated	myelinate	VERB
fnp-2971	36	30	fibers	fiber	NOUN
fnp-2971	36	31	;	;	PUNCT
fnp-2971	36	32	2	2	X
fnp-2971	36	33	)	)	PUNCT
fnp-2971	36	34	moderate	moderate	ADJ
fnp-2971	36	35	loss	loss	NOUN
fnp-2971	36	36	of	of	ADP
fnp-2971	36	37	myelinated	myelinated	ADJ
fnp-2971	36	38	fibers	fiber	NOUN
fnp-2971	36	39	with	with	ADP
fnp-2971	36	40	or	or	CCONJ
fnp-2971	36	41	without	without	ADP
fnp-2971	36	42	axonal	axonal	ADJ
fnp-2971	36	43	spheroids	spheroid	NOUN
fnp-2971	36	44	;	;	PUNCT
fnp-2971	36	45	and	and	CCONJ
fnp-2971	36	46	3	3	X
fnp-2971	36	47	)	)	PUNCT
fnp-2971	36	48	a	a	DET
fnp-2971	36	49	leukodystrophy	leukodystrophy	NOUN
fnp-2971	36	50	-	-	PUNCT
fnp-2971	36	51	like	like	ADJ
fnp-2971	36	52	pattern	pattern	NOUN
fnp-2971	36	53	with	with	ADP
fnp-2971	36	54	severe	severe	ADJ
fnp-2971	36	55	confluent	confluent	ADJ
fnp-2971	36	56	axonal	axonal	ADJ
fnp-2971	36	57	and	and	CCONJ
fnp-2971	36	58	myelin	myelin	NOUN
fnp-2971	36	59	loss	loss	NOUN
fnp-2971	36	60	.	.	PUNCT
fnp-2971	37	1	digital	digital	ADJ
fnp-2971	37	2	images	image	NOUN
fnp-2971	37	3	of	of	ADP
fnp-2971	37	4	lfb	lfb	PROPN
fnp-2971	37	5	-	-	PUNCT
fnp-2971	37	6	he	he	PRON
fnp-2971	37	7	,	,	PUNCT
fnp-2971	37	8	app	app	PROPN
fnp-2971	37	9	,	,	PUNCT
fnp-2971	37	10	hla	hla	PROPN
fnp-2971	37	11	-	-	PUNCT
fnp-2971	37	12	dr	dr	PROPN
fnp-2971	37	13	,	,	PUNCT
fnp-2971	37	14	iba1	iba1	PROPN
fnp-2971	37	15	,	,	PUNCT
fnp-2971	37	16	and	and	CCONJ
fnp-2971	37	17	smi31	smi31	NOUN
fnp-2971	37	18	staining	stain	VERB
fnp-2971	37	19	slides	slide	NOUN
fnp-2971	37	20	were	be	AUX
fnp-2971	37	21	obtained	obtain	VERB
fnp-2971	37	22	using	use	VERB
fnp-2971	37	23	the	the	DET
fnp-2971	37	24	aperio	aperio	NOUN
fnp-2971	37	25	system	system	NOUN
fnp-2971	37	26	.	.	PUNCT
fnp-2971	38	1	particular	particular	ADJ
fnp-2971	38	2	areas	area	NOUN
fnp-2971	38	3	of	of	ADP
fnp-2971	38	4	interest	interest	NOUN
fnp-2971	38	5	were	be	AUX
fnp-2971	38	6	demarcated	demarcate	VERB
fnp-2971	38	7	on	on	ADP
fnp-2971	38	8	the	the	DET
fnp-2971	38	9	computer	computer	NOUN
fnp-2971	38	10	screen	screen	NOUN
fnp-2971	38	11	of	of	ADP
fnp-2971	38	12	these	these	DET
fnp-2971	38	13	digital	digital	ADJ
fnp-2971	38	14	images	image	NOUN
fnp-2971	38	15	.	.	PUNCT
fnp-2971	39	1	at	at	ADV
fnp-2971	39	2	least	least	ADJ
fnp-2971	39	3	five	five	NUM
fnp-2971	39	4	areas	area	NOUN
fnp-2971	39	5	for	for	ADP
fnp-2971	39	6	each	each	DET
fnp-2971	39	7	pathological	pathological	ADJ
fnp-2971	39	8	stage	stage	NOUN
fnp-2971	39	9	from	from	ADP
fnp-2971	39	10	each	each	DET
fnp-2971	39	11	case	case	NOUN
fnp-2971	39	12	were	be	AUX
fnp-2971	39	13	examined	examine	VERB
fnp-2971	39	14	.	.	PUNCT
fnp-2971	40	1	the	the	DET
fnp-2971	40	2	pathological	pathological	ADJ
fnp-2971	40	3	features	feature	NOUN
fnp-2971	40	4	,	,	PUNCT
fnp-2971	40	5	regardless	regardless	ADV
fnp-2971	40	6	of	of	ADP
fnp-2971	40	7	the	the	DET
fnp-2971	40	8	size	size	NOUN
fnp-2971	40	9	of	of	ADP
fnp-2971	40	10	the	the	DET
fnp-2971	40	11	lesion	lesion	NOUN
fnp-2971	40	12	,	,	PUNCT
fnp-2971	40	13	defined	define	VERB
fnp-2971	40	14	the	the	DET
fnp-2971	40	15	pathological	pathological	ADJ
fnp-2971	40	16	stages	stage	NOUN
fnp-2971	40	17	.	.	PUNCT
fnp-2971	41	1	any	any	DET
fnp-2971	41	2	lesion	lesion	NOUN
fnp-2971	41	3	can	can	AUX
fnp-2971	41	4	range	range	VERB
fnp-2971	41	5	from	from	ADP
fnp-2971	41	6	very	very	ADV
fnp-2971	41	7	small	small	ADJ
fnp-2971	41	8	areas	area	NOUN
fnp-2971	41	9	(	(	PUNCT
fnp-2971	41	10	usually	usually	ADV
fnp-2971	41	11	in	in	ADP
fnp-2971	41	12	stage	stage	NOUN
fnp-2971	41	13	1	1	NUM
fnp-2971	41	14	pathology	pathology	NOUN
fnp-2971	41	15	)	)	PUNCT
fnp-2971	41	16	to	to	ADP
fnp-2971	41	17	very	very	ADV
fnp-2971	41	18	large	large	ADJ
fnp-2971	41	19	(	(	PUNCT
fnp-2971	41	20	common	common	ADJ
fnp-2971	41	21	in	in	ADP
fnp-2971	41	22	stage	stage	NOUN
fnp-2971	41	23	3	3	NUM
fnp-2971	41	24	pathology	pathology	NOUN
fnp-2971	41	25	)	)	PUNCT
fnp-2971	41	26	.	.	PUNCT
fnp-2971	42	1	a	a	DET
fnp-2971	42	2	single	single	ADJ
fnp-2971	42	3	area	area	NOUN
fnp-2971	42	4	in	in	ADP
fnp-2971	42	5	the	the	DET
fnp-2971	42	6	white	white	ADJ
fnp-2971	42	7	matter	matter	NOUN
fnp-2971	42	8	could	could	AUX
fnp-2971	42	9	contain	contain	VERB
fnp-2971	42	10	more	more	ADJ
fnp-2971	42	11	than	than	ADP
fnp-2971	42	12	one	one	NUM
fnp-2971	42	13	pathological	pathological	ADJ
fnp-2971	42	14	stage	stage	NOUN
fnp-2971	42	15	.	.	PUNCT
fnp-2971	43	1	axonal	axonal	ADJ
fnp-2971	43	2	spheroids	spheroid	NOUN
fnp-2971	43	3	and	and	CCONJ
fnp-2971	43	4	the	the	DET
fnp-2971	43	5	hla	hla	PROPN
fnp-2971	43	6	-	-	PUNCT
fnp-2971	43	7	dr	dr	NOUN
fnp-2971	43	8	-	-	PUNCT
fnp-2971	43	9	expressing	express	VERB
fnp-2971	43	10	cells	cell	NOUN
fnp-2971	43	11	were	be	AUX
fnp-2971	43	12	semi	semi	ADJ
fnp-2971	43	13	-	-	ADJ
fnp-2971	43	14	quantified	quantified	ADJ
fnp-2971	43	15	(	(	PUNCT
fnp-2971	43	16	see	see	VERB
fnp-2971	43	17	supplemental	supplemental	ADJ
fnp-2971	43	18	figure	figure	NOUN
fnp-2971	43	19	1	1	NUM
fnp-2971	43	20	)	)	PUNCT
fnp-2971	43	21	and	and	CCONJ
fnp-2971	43	22	lesions	lesion	NOUN
fnp-2971	43	23	were	be	AUX
fnp-2971	43	24	assigned	assign	VERB
fnp-2971	43	25	a	a	DET
fnp-2971	43	26	score	score	NOUN
fnp-2971	43	27	of	of	ADP
fnp-2971	43	28	0–3	0–3	PROPN
fnp-2971	43	29	.	.	PUNCT
fnp-2971	44	1	the	the	DET
fnp-2971	44	2	scoring	scoring	NOUN
fnp-2971	44	3	for	for	ADP
fnp-2971	44	4	axonal	axonal	ADJ
fnp-2971	44	5	spheroids	spheroid	NOUN
fnp-2971	44	6	was	be	AUX
fnp-2971	44	7	as	as	SCONJ
fnp-2971	44	8	follows	follow	VERB
fnp-2971	44	9	:	:	PUNCT
fnp-2971	44	10	0	0	NUM
fnp-2971	44	11	=	=	SYM
fnp-2971	44	12	absence	absence	NOUN
fnp-2971	44	13	of	of	ADP
fnp-2971	44	14	axonal	axonal	ADJ
fnp-2971	44	15	spheroids	spheroid	NOUN
fnp-2971	44	16	;	;	PUNCT
fnp-2971	44	17	1	1	NUM
fnp-2971	44	18	=	=	SYM
fnp-2971	44	19	few	few	ADJ
fnp-2971	44	20	axonal	axonal	ADJ
fnp-2971	44	21	spheroids	spheroid	NOUN
fnp-2971	44	22	(	(	PUNCT
fnp-2971	44	23	1–2	1–2	NUM
fnp-2971	44	24	/	/	SYM
fnp-2971	44	25	high	high	ADJ
fnp-2971	44	26	power	power	NOUN
fnp-2971	44	27	field	field	NOUN
fnp-2971	44	28	;	;	PUNCT
fnp-2971	44	29	hpf	hpf	PROPN
fnp-2971	44	30	)	)	PUNCT
fnp-2971	44	31	;	;	PUNCT
fnp-2971	44	32	2	2	NUM
fnp-2971	44	33	=	=	SYM
fnp-2971	44	34	moderate	moderate	ADJ
fnp-2971	44	35	number	number	NOUN
fnp-2971	44	36	of	of	ADP
fnp-2971	44	37	axonal	axonal	ADJ
fnp-2971	44	38	spheroids	spheroid	NOUN
fnp-2971	44	39	(	(	PUNCT
fnp-2971	44	40	3–5	3–5	PROPN
fnp-2971	44	41	/	/	SYM
fnp-2971	44	42	hpf	hpf	NOUN
fnp-2971	44	43	)	)	PUNCT
fnp-2971	44	44	;	;	PUNCT
fnp-2971	44	45	and	and	CCONJ
fnp-2971	44	46	3	3	X
fnp-2971	44	47	=	=	SYM
fnp-2971	44	48	frequent	frequent	ADJ
fnp-2971	44	49	axonal	axonal	ADJ
fnp-2971	44	50	spheroids	spheroid	NOUN
fnp-2971	44	51	(	(	PUNCT
fnp-2971	44	52	6	6	NUM
fnp-2971	44	53	or	or	CCONJ
fnp-2971	44	54	more	more	ADJ
fnp-2971	44	55	/	/	SYM
fnp-2971	44	56	hpf	hpf	NOUN
fnp-2971	44	57	)	)	PUNCT
fnp-2971	44	58	.	.	PUNCT
fnp-2971	45	1	for	for	ADP
fnp-2971	45	2	the	the	DET
fnp-2971	45	3	hla	hla	PROPN
fnp-2971	45	4	-	-	PUNCT
fnp-2971	45	5	dr	dr	PROPN
fnp-2971	45	6	and/or	and/or	CCONJ
fnp-2971	45	7	iba1	iba1	NOUN
fnp-2971	45	8	-	-	PUNCT
fnp-2971	45	9	expressing	express	VERB
fnp-2971	45	10	cells	cell	NOUN
fnp-2971	45	11	,	,	PUNCT
fnp-2971	45	12	we	we	PRON
fnp-2971	45	13	subdivided	subdivide	VERB
fnp-2971	45	14	them	they	PRON
fnp-2971	45	15	into	into	ADP
fnp-2971	45	16	ramified	ramified	ADJ
fnp-2971	45	17	-	-	PUNCT
fnp-2971	45	18	phenotype	phenotype	NOUN
fnp-2971	45	19	and	and	CCONJ
fnp-2971	45	20	amoeboid	amoeboid	NOUN
fnp-2971	45	21	-	-	PUNCT
fnp-2971	45	22	phenotype	phenotype	NOUN
fnp-2971	45	23	.	.	PUNCT
fnp-2971	46	1	their	their	PRON
fnp-2971	46	2	numbers	number	NOUN
fnp-2971	46	3	were	be	AUX
fnp-2971	46	4	scored	score	VERB
fnp-2971	46	5	in	in	ADP
fnp-2971	46	6	the	the	DET
fnp-2971	46	7	following	follow	VERB
fnp-2971	46	8	manner	manner	NOUN
fnp-2971	46	9	:	:	PUNCT
fnp-2971	46	10	0	0	NUM
fnp-2971	46	11	=	=	SYM
fnp-2971	46	12	no	no	DET
fnp-2971	46	13	hla	hla	PROPN
fnp-2971	46	14	-	-	PUNCT
fnp-2971	46	15	dr	dr	PROPN
fnp-2971	46	16	staining	staining	NOUN
fnp-2971	46	17	;	;	PUNCT
fnp-2971	46	18	1=	1=	NUM
fnp-2971	46	19	few	few	ADJ
fnp-2971	46	20	cells	cell	NOUN
fnp-2971	46	21	(	(	PUNCT
fnp-2971	46	22	1–9	1–9	PROPN
fnp-2971	46	23	/	/	SYM
fnp-2971	46	24	hpf	hpf	NOUN
fnp-2971	46	25	)	)	PUNCT
fnp-2971	46	26	;	;	PUNCT
fnp-2971	46	27	2	2	NUM
fnp-2971	46	28	=	=	SYM
fnp-2971	46	29	moderate	moderate	ADJ
fnp-2971	46	30	number	number	NOUN
fnp-2971	46	31	of	of	ADP
fnp-2971	46	32	cells	cell	NOUN
fnp-2971	46	33	(	(	PUNCT
fnp-2971	46	34	10–19	10–19	NUM
fnp-2971	46	35	/	/	SYM
fnp-2971	46	36	hpf	hpf	NOUN
fnp-2971	46	37	)	)	PUNCT
fnp-2971	46	38	;	;	PUNCT
fnp-2971	46	39	and	and	CCONJ
fnp-2971	46	40	3	3	NUM
fnp-2971	46	41	=	=	SYM
fnp-2971	46	42	frequent	frequent	ADJ
fnp-2971	46	43	cells	cell	NOUN
fnp-2971	46	44	(	(	PUNCT
fnp-2971	46	45	20	20	NUM
fnp-2971	46	46	or	or	CCONJ
fnp-2971	46	47	more	more	ADJ
fnp-2971	46	48	/	/	SYM
fnp-2971	46	49	hpf	hpf	NOUN
fnp-2971	46	50	)	)	PUNCT
fnp-2971	46	51	.	.	PUNCT
fnp-2971	47	1	several	several	ADJ
fnp-2971	47	2	morphological	morphological	ADJ
fnp-2971	47	3	shapes	shape	NOUN
fnp-2971	47	4	of	of	ADP
fnp-2971	47	5	microglia	microglia	NOUN
fnp-2971	47	6	have	have	AUX
fnp-2971	47	7	been	be	AUX
fnp-2971	47	8	identified	identify	VERB
fnp-2971	47	9	(	(	PUNCT
fnp-2971	47	10	10	10	NUM
fnp-2971	47	11	)	)	PUNCT
fnp-2971	47	12	.	.	PUNCT
fnp-2971	48	1	however	however	ADV
fnp-2971	48	2	,	,	PUNCT
fnp-2971	48	3	for	for	ADP
fnp-2971	48	4	the	the	DET
fnp-2971	48	5	sake	sake	NOUN
fnp-2971	48	6	of	of	ADP
fnp-2971	48	7	simplicity	simplicity	NOUN
fnp-2971	48	8	,	,	PUNCT
fnp-2971	48	9	in	in	ADP
fnp-2971	48	10	this	this	DET
fnp-2971	48	11	study	study	NOUN
fnp-2971	48	12	we	we	PRON
fnp-2971	48	13	divided	divide	VERB
fnp-2971	48	14	microglia	microglia	NOUN
fnp-2971	48	15	into	into	ADP
fnp-2971	48	16	two	two	NUM
fnp-2971	48	17	different	different	ADJ
fnp-2971	48	18	types	type	NOUN
fnp-2971	48	19	:	:	PUNCT
fnp-2971	48	20	1	1	X
fnp-2971	48	21	)	)	PUNCT
fnp-2971	48	22	ramified	ramify	VERB
fnp-2971	48	23	microglia	microglia	NOUN
fnp-2971	48	24	with	with	ADP
fnp-2971	48	25	a	a	DET
fnp-2971	48	26	small	small	ADJ
fnp-2971	48	27	cell	cell	NOUN
fnp-2971	48	28	body	body	NOUN
fnp-2971	48	29	with	with	ADP
fnp-2971	48	30	branching	branch	VERB
fnp-2971	48	31	processes	process	NOUN
fnp-2971	48	32	radiating	radiate	VERB
fnp-2971	48	33	from	from	ADP
fnp-2971	48	34	the	the	DET
fnp-2971	48	35	cell	cell	NOUN
fnp-2971	48	36	bodies	body	NOUN
fnp-2971	48	37	,	,	PUNCT
fnp-2971	48	38	including	include	VERB
fnp-2971	48	39	a	a	DET
fnp-2971	48	40	broad	broad	ADJ
fnp-2971	48	41	spectrum	spectrum	NOUN
fnp-2971	48	42	of	of	ADP
fnp-2971	48	43	reactive	reactive	ADJ
fnp-2971	48	44	microglial	microglial	ADJ
fnp-2971	48	45	shapes	shape	NOUN
fnp-2971	48	46	with	with	ADP
fnp-2971	48	47	varying	vary	VERB
fnp-2971	48	48	lengths	length	NOUN
fnp-2971	48	49	and	and	CCONJ
fnp-2971	48	50	thicknesses	thickness	NOUN
fnp-2971	48	51	of	of	ADP
fnp-2971	48	52	processes	process	NOUN
fnp-2971	48	53	and	and	CCONJ
fnp-2971	48	54	different	different	ADJ
fnp-2971	48	55	cell	cell	NOUN
fnp-2971	48	56	body	body	NOUN
fnp-2971	48	57	dimensions	dimension	NOUN
fnp-2971	48	58	;	;	PUNCT
fnp-2971	48	59	and	and	CCONJ
fnp-2971	48	60	2	2	X
fnp-2971	48	61	)	)	PUNCT
fnp-2971	48	62	amoeboid	amoeboid	ADJ
fnp-2971	48	63	microglia	microglia	NOUN
fnp-2971	48	64	with	with	ADP
fnp-2971	48	65	a	a	DET
fnp-2971	48	66	macrophage	macrophage	NOUN
fnp-2971	48	67	-	-	PUNCT
fnp-2971	48	68	like	like	ADJ
fnp-2971	48	69	or	or	CCONJ
fnp-2971	48	70	amoeboid	amoeboid	ADJ
fnp-2971	48	71	phenotype	phenotype	NOUN
fnp-2971	48	72	characterized	characterize	VERB
fnp-2971	48	73	by	by	ADP
fnp-2971	48	74	a	a	DET
fnp-2971	48	75	round	round	ADJ
fnp-2971	48	76	cytoplasm	cytoplasm	NOUN
fnp-2971	48	77	with	with	ADP
fnp-2971	48	78	no	no	DET
fnp-2971	48	79	processes	process	NOUN
fnp-2971	48	80	.	.	PUNCT
fnp-2971	49	1	the	the	DET
fnp-2971	49	2	white	white	ADJ
fnp-2971	49	3	matter	matter	NOUN
fnp-2971	49	4	from	from	ADP
fnp-2971	49	5	the	the	DET
fnp-2971	49	6	same	same	ADJ
fnp-2971	49	7	autopsy	autopsy	ADJ
fnp-2971	49	8	tissue	tissue	NOUN
fnp-2971	49	9	in	in	ADP
fnp-2971	49	10	the	the	DET
fnp-2971	49	11	areas	area	NOUN
fnp-2971	49	12	adjacent	adjacent	ADJ
fnp-2971	49	13	to	to	ADP
fnp-2971	49	14	the	the	DET
fnp-2971	49	15	affected	affect	VERB
fnp-2971	49	16	white	white	ADJ
fnp-2971	49	17	matter	matter	NOUN
fnp-2971	49	18	and	and	CCONJ
fnp-2971	49	19	separate	separate	ADJ
fnp-2971	49	20	from	from	ADP
fnp-2971	49	21	it	it	PRON
fnp-2971	49	22	was	be	AUX
fnp-2971	49	23	used	use	VERB
fnp-2971	49	24	as	as	ADP
fnp-2971	49	25	control	control	NOUN
fnp-2971	49	26	tissue	tissue	NOUN
fnp-2971	49	27	to	to	PART
fnp-2971	49	28	confirm	confirm	VERB
fnp-2971	49	29	the	the	DET
fnp-2971	49	30	reliability	reliability	NOUN
fnp-2971	49	31	of	of	ADP
fnp-2971	49	32	the	the	DET
fnp-2971	49	33	immunostains	immunostain	NOUN
fnp-2971	49	34	(	(	PUNCT
fnp-2971	49	35	i.e.	i.e.	X
fnp-2971	49	36	internal	internal	ADJ
fnp-2971	49	37	positive	positive	ADJ
fnp-2971	49	38	control	control	NOUN
fnp-2971	49	39	)	)	PUNCT
fnp-2971	49	40	used	use	VERB
fnp-2971	49	41	in	in	ADP
fnp-2971	49	42	this	this	DET
fnp-2971	49	43	study	study	NOUN
fnp-2971	49	44	.	.	PUNCT
fnp-2971	50	1	as	as	SCONJ
fnp-2971	50	2	the	the	DET
fnp-2971	50	3	autopsy	autopsy	ADJ
fnp-2971	50	4	brain	brain	NOUN
fnp-2971	50	5	tissue	tissue	NOUN
fnp-2971	50	6	from	from	ADP
fnp-2971	50	7	relatively	relatively	ADV
fnp-2971	50	8	normal	normal	ADJ
fnp-2971	50	9	cases	case	NOUN
fnp-2971	50	10	was	be	AUX
fnp-2971	50	11	not	not	PART
fnp-2971	50	12	expected	expect	VERB
fnp-2971	50	13	to	to	PART
fnp-2971	50	14	show	show	VERB
fnp-2971	50	15	axonal	axonal	ADJ
fnp-2971	50	16	spheroids	spheroid	NOUN
fnp-2971	50	17	,	,	PUNCT
fnp-2971	50	18	we	we	PRON
fnp-2971	50	19	did	do	AUX
fnp-2971	50	20	not	not	PART
fnp-2971	50	21	use	use	VERB
fnp-2971	50	22	such	such	ADJ
fnp-2971	50	23	controls	control	NOUN
fnp-2971	50	24	in	in	ADP
fnp-2971	50	25	our	our	PRON
fnp-2971	50	26	study	study	NOUN
fnp-2971	50	27	.	.	PUNCT
fnp-2971	51	1	results	result	VERB
fnp-2971	51	2	the	the	DET
fnp-2971	51	3	clinical	clinical	ADJ
fnp-2971	51	4	information	information	NOUN
fnp-2971	51	5	for	for	ADP
fnp-2971	51	6	the	the	DET
fnp-2971	51	7	first	first	ADJ
fnp-2971	51	8	four	four	NUM
fnp-2971	51	9	cases	case	NOUN
fnp-2971	51	10	has	have	AUX
fnp-2971	51	11	been	be	AUX
fnp-2971	51	12	discussed	discuss	VERB
fnp-2971	51	13	before	before	ADV
fnp-2971	51	14	(	(	PUNCT
fnp-2971	51	15	1	1	NUM
fnp-2971	51	16	)	)	PUNCT
fnp-2971	51	17	and	and	CCONJ
fnp-2971	51	18	is	be	AUX
fnp-2971	51	19	summarized	summarize	VERB
fnp-2971	51	20	in	in	ADP
fnp-2971	51	21	table	table	NOUN
fnp-2971	51	22	1	1	NUM
fnp-2971	51	23	.	.	PUNCT
fnp-2971	52	1	in	in	ADP
fnp-2971	52	2	general	general	ADJ
fnp-2971	52	3	,	,	PUNCT
fnp-2971	52	4	clinical	clinical	ADJ
fnp-2971	52	5	presentations	presentation	NOUN
fnp-2971	52	6	were	be	AUX
fnp-2971	52	7	dependent	dependent	ADJ
fnp-2971	52	8	on	on	ADP
fnp-2971	52	9	the	the	DET
fnp-2971	52	10	location	location	NOUN
fnp-2971	52	11	of	of	ADP
fnp-2971	52	12	the	the	DET
fnp-2971	52	13	white	white	ADJ
fnp-2971	52	14	matter	matter	NOUN
fnp-2971	52	15	areas	area	NOUN
fnp-2971	52	16	affected	affect	VERB
fnp-2971	52	17	,	,	PUNCT
fnp-2971	52	18	which	which	PRON
fnp-2971	52	19	were	be	AUX
fnp-2971	52	20	preferentially	preferentially	ADV
fnp-2971	52	21	frontotemporal	frontotemporal	ADJ
fnp-2971	52	22	.	.	PUNCT
fnp-2971	53	1	case	case	NOUN
fnp-2971	53	2	5	5	NUM
fnp-2971	53	3	was	be	AUX
fnp-2971	53	4	a	a	DET
fnp-2971	53	5	57	57	NUM
fnp-2971	53	6	-	-	PUNCT
fnp-2971	53	7	year	year	NOUN
fnp-2971	53	8	-	-	PUNCT
fnp-2971	53	9	old	old	ADJ
fnp-2971	53	10	female	female	NOUN
fnp-2971	53	11	who	who	PRON
fnp-2971	53	12	had	have	VERB
fnp-2971	53	13	a	a	DET
fnp-2971	53	14	rapid	rapid	ADJ
fnp-2971	53	15	2	2	NUM
fnp-2971	53	16	-	-	PUNCT
fnp-2971	53	17	year	year	NOUN
fnp-2971	53	18	progression	progression	NOUN
fnp-2971	53	19	of	of	ADP
fnp-2971	53	20	neurobehavioral	neurobehavioral	ADJ
fnp-2971	53	21	symptoms	symptom	NOUN
fnp-2971	53	22	(	(	PUNCT
fnp-2971	53	23	self	self	NOUN
fnp-2971	53	24	-	-	PUNCT
fnp-2971	53	25	neglect	neglect	NOUN
fnp-2971	53	26	and	and	CCONJ
fnp-2971	53	27	apathy	apathy	NOUN
fnp-2971	53	28	)	)	PUNCT
fnp-2971	53	29	and	and	CCONJ
fnp-2971	53	30	seizures	seizure	NOUN
fnp-2971	53	31	until	until	ADP
fnp-2971	53	32	death	death	NOUN
fnp-2971	53	33	.	.	PUNCT
fnp-2971	54	1	she	she	PRON
fnp-2971	54	2	had	have	VERB
fnp-2971	54	3	a	a	DET
fnp-2971	54	4	sister	sister	NOUN
fnp-2971	54	5	with	with	ADP
fnp-2971	54	6	cognitive	cognitive	ADJ
fnp-2971	54	7	impairments	impairment	NOUN
fnp-2971	54	8	,	,	PUNCT
fnp-2971	54	9	but	but	CCONJ
fnp-2971	54	10	slower	slow	ADJ
fnp-2971	54	11	progression	progression	NOUN
fnp-2971	54	12	.	.	PUNCT
fnp-2971	55	1	both	both	DET
fnp-2971	55	2	patients	patient	NOUN
fnp-2971	55	3	had	have	VERB
fnp-2971	55	4	a	a	DET
fnp-2971	55	5	previously	previously	ADV
fnp-2971	55	6	unreported	unreported	ADJ
fnp-2971	55	7	variant	variant	NOUN
fnp-2971	55	8	of	of	ADP
fnp-2971	55	9	csf1r	csf1r	X
fnp-2971	55	10	(	(	PUNCT
fnp-2971	55	11	c.2563	c.2563	PROPN
fnp-2971	55	12	c	c	PROPN
fnp-2971	55	13	>	>	PROPN
fnp-2971	55	14	t	t	PROPN
fnp-2971	55	15	)	)	PUNCT
fnp-2971	55	16	mutation	mutation	NOUN
fnp-2971	55	17	(	(	PUNCT
fnp-2971	55	18	11	11	NUM
fnp-2971	55	19	)	)	PUNCT
fnp-2971	55	20	.	.	PUNCT
fnp-2971	56	1	their	their	PRON
fnp-2971	56	2	mother	mother	NOUN
fnp-2971	56	3	had	have	VERB
fnp-2971	56	4	a	a	DET
fnp-2971	56	5	history	history	NOUN
fnp-2971	56	6	of	of	ADP
fnp-2971	56	7	early	early	ADJ
fnp-2971	56	8	-	-	PUNCT
fnp-2971	56	9	onset	onset	NOUN
fnp-2971	56	10	dementia	dementia	NOUN
fnp-2971	56	11	.	.	PUNCT
fnp-2971	57	1	case	case	NOUN
fnp-2971	57	2	6	6	NUM
fnp-2971	57	3	was	be	AUX
fnp-2971	57	4	a	a	DET
fnp-2971	57	5	38	38	NUM
fnp-2971	57	6	-	-	PUNCT
fnp-2971	57	7	year	year	NOUN
fnp-2971	57	8	-	-	PUNCT
fnp-2971	57	9	old	old	ADJ
fnp-2971	57	10	female	female	NOUN
fnp-2971	57	11	with	with	ADP
fnp-2971	57	12	a	a	DET
fnp-2971	57	13	rapid	rapid	ADJ
fnp-2971	57	14	decline	decline	NOUN
fnp-2971	57	15	in	in	ADP
fnp-2971	57	16	cognition	cognition	NOUN
fnp-2971	57	17	and	and	CCONJ
fnp-2971	57	18	shortand	shortand	NOUN
fnp-2971	57	19	long	long	ADJ
fnp-2971	57	20	-	-	PUNCT
fnp-2971	57	21	term	term	NOUN
fnp-2971	57	22	memory	memory	NOUN
fnp-2971	57	23	impairment	impairment	NOUN
fnp-2971	57	24	.	.	PUNCT
fnp-2971	58	1	she	she	PRON
fnp-2971	58	2	was	be	AUX
fnp-2971	58	3	placed	place	VERB
fnp-2971	58	4	in	in	ADP
fnp-2971	58	5	a	a	DET
fnp-2971	58	6	nursing	nursing	NOUN
fnp-2971	58	7	home	home	NOUN
fnp-2971	58	8	as	as	SCONJ
fnp-2971	58	9	she	she	PRON
fnp-2971	58	10	required	require	VERB
fnp-2971	58	11	assistance	assistance	NOUN
fnp-2971	58	12	for	for	ADP
fnp-2971	58	13	daily	daily	ADJ
fnp-2971	58	14	life	life	NOUN
fnp-2971	58	15	activities	activity	NOUN
fnp-2971	58	16	and	and	CCONJ
fnp-2971	58	17	died	die	VERB
fnp-2971	58	18	two	two	NUM
fnp-2971	58	19	years	year	NOUN
fnp-2971	58	20	after	after	ADP
fnp-2971	58	21	the	the	DET
fnp-2971	58	22	initial	initial	ADJ
fnp-2971	58	23	presentation	presentation	NOUN
fnp-2971	58	24	.	.	PUNCT
fnp-2971	59	1	her	her	PRON
fnp-2971	59	2	first	first	ADJ
fnp-2971	59	3	-	-	PUNCT
fnp-2971	59	4	degree	degree	NOUN
fnp-2971	59	5	relatives	relative	NOUN
fnp-2971	59	6	had	have	VERB
fnp-2971	59	7	a	a	DET
fnp-2971	59	8	positive	positive	ADJ
fnp-2971	59	9	history	history	NOUN
fnp-2971	59	10	of	of	ADP
fnp-2971	59	11	dementia	dementia	NOUN
fnp-2971	59	12	.	.	PUNCT
fnp-2971	60	1	she	she	PRON
fnp-2971	60	2	had	have	VERB
fnp-2971	60	3	another	another	DET
fnp-2971	60	4	novel	novel	ADJ
fnp-2971	60	5	variant	variant	NOUN
fnp-2971	60	6	of	of	ADP
fnp-2971	60	7	csf1r	csf1r	X
fnp-2971	60	8	(	(	PUNCT
fnp-2971	60	9	c.2377a	c.2377a	NOUN
fnp-2971	60	10	>	>	NOUN
fnp-2971	60	11	g	g	NOUN
fnp-2971	60	12	)	)	PUNCT
fnp-2971	60	13	mutation	mutation	NOUN
fnp-2971	60	14	.	.	PUNCT
fnp-2971	61	1	the	the	DET
fnp-2971	61	2	csf1r	csf1r	PROPN
fnp-2971	61	3	gene	gene	NOUN
fnp-2971	61	4	mutational	mutational	ADJ
fnp-2971	61	5	analysis	analysis	NOUN
fnp-2971	61	6	for	for	ADP
fnp-2971	61	7	the	the	DET
fnp-2971	61	8	first	first	ADJ
fnp-2971	61	9	4	4	NUM
fnp-2971	61	10	cases	case	NOUN
fnp-2971	61	11	was	be	AUX
fnp-2971	61	12	unsuccessful	unsuccessful	ADJ
fnp-2971	61	13	as	as	SCONJ
fnp-2971	61	14	the	the	DET
fnp-2971	61	15	quality	quality	NOUN
fnp-2971	61	16	of	of	ADP
fnp-2971	61	17	the	the	DET
fnp-2971	61	18	dna	dna	PROPN
fnp-2971	61	19	extracted	extract	VERB
fnp-2971	61	20	from	from	ADP
fnp-2971	61	21	fixed	fixed	ADJ
fnp-2971	61	22	tissue	tissue	NOUN
fnp-2971	61	23	was	be	AUX
fnp-2971	61	24	inadequate	inadequate	ADJ
fnp-2971	61	25	,	,	PUNCT
fnp-2971	61	26	as	as	SCONJ
fnp-2971	61	27	discussed	discuss	VERB
fnp-2971	61	28	before	before	ADV
fnp-2971	61	29	(	(	PUNCT
fnp-2971	61	30	1	1	NUM
fnp-2971	61	31	)	)	PUNCT
fnp-2971	61	32	.	.	PUNCT
fnp-2971	62	1	both	both	DET
fnp-2971	62	2	mutations	mutation	NOUN
fnp-2971	62	3	were	be	AUX
fnp-2971	62	4	analyzed	analyze	VERB
fnp-2971	62	5	via	via	ADP
fnp-2971	62	6	the	the	DET
fnp-2971	62	7	varsome	varsome	NOUN
fnp-2971	62	8	website	website	NOUN
fnp-2971	62	9	(	(	PUNCT
fnp-2971	62	10	https://varsome.com/variant/hg19/nm_005211.3%3ac.2563c%3et	https://varsome.com/variant/hg19/nm_005211.3%3ac.2563c%3et	NOUN
fnp-2971	62	11	and	and	CCONJ
fnp-2971	62	12	https://varsome.com/variant/hg19/nm_005211.3%3ac.2377a%3eg	https://varsome.com/variant/hg19/nm_005211.3%3ac.2377a%3eg	ADJ
fnp-2971	62	13	)	)	PUNCT
fnp-2971	62	14	.	.	PUNCT
fnp-2971	63	1	various	various	ADJ
fnp-2971	63	2	software	software	NOUN
fnp-2971	63	3	tools	tool	NOUN
fnp-2971	63	4	including	include	VERB
fnp-2971	63	5	dann	dann	NOUN
fnp-2971	63	6	(	(	PUNCT
fnp-2971	63	7	score	score	NOUN
fnp-2971	63	8	0.9991	0.9991	NUM
fnp-2971	63	9	and	and	CCONJ
fnp-2971	63	10	0.9989	0.9989	NUM
fnp-2971	63	11	,	,	PUNCT
fnp-2971	63	12	respectively	respectively	ADV
fnp-2971	63	13	)	)	PUNCT
fnp-2971	63	14	,	,	PUNCT
fnp-2971	63	15	mutationtaster	mutationtaster	NOUN
fnp-2971	63	16	(	(	PUNCT
fnp-2971	63	17	disease	disease	NOUN
fnp-2971	63	18	causing	cause	VERB
fnp-2971	63	19	)	)	PUNCT
fnp-2971	63	20	,	,	PUNCT
fnp-2971	63	21	fathmm	fathmm	NOUN
fnp-2971	63	22	(	(	PUNCT
fnp-2971	63	23	damaging	damaging	ADJ
fnp-2971	63	24	)	)	PUNCT
fnp-2971	63	25	,	,	PUNCT
fnp-2971	63	26	fathmm	fathmm	NOUN
fnp-2971	63	27	-	-	PUNCT
fnp-2971	63	28	mkl	mkl	PROPN
fnp-2971	63	29	(	(	PUNCT
fnp-2971	63	30	damaging	damaging	NOUN
fnp-2971	63	31	)	)	PUNCT
fnp-2971	63	32	,	,	PUNCT
fnp-2971	63	33	metasvm	metasvm	ADJ
fnp-2971	63	34	(	(	PUNCT
fnp-2971	63	35	damaging	damaging	ADJ
fnp-2971	63	36	)	)	PUNCT
fnp-2971	63	37	,	,	PUNCT
fnp-2971	63	38	and	and	CCONJ
fnp-2971	63	39	metalr	metalr	NOUN
fnp-2971	63	40	(	(	PUNCT
fnp-2971	63	41	damaging	damaging	ADJ
fnp-2971	63	42	)	)	PUNCT
fnp-2971	63	43	predicted	predict	VERB
fnp-2971	63	44	pathogenicity	pathogenicity	NOUN
fnp-2971	63	45	,	,	PUNCT
fnp-2971	63	46	which	which	PRON
fnp-2971	63	47	was	be	AUX
fnp-2971	63	48	supported	support	VERB
fnp-2971	63	49	by	by	ADP
fnp-2971	63	50	locations	location	NOUN
fnp-2971	63	51	within	within	ADP
fnp-2971	63	52	the	the	DET
fnp-2971	63	53	protein	protein	NOUN
fnp-2971	63	54	kinase	kinase	NOUN
fnp-2971	63	55	functional	functional	ADJ
fnp-2971	63	56	domain	domain	NOUN
fnp-2971	63	57	.	.	PUNCT
fnp-2971	64	1	antibodies	antibodie	VERB
fnp-2971	64	2	against	against	ADP
fnp-2971	64	3	hla	hla	PROPN
fnp-2971	64	4	-	-	PUNCT
fnp-2971	64	5	dr	dr	PROPN
fnp-2971	64	6	and	and	CCONJ
fnp-2971	64	7	iba1	iba1	PROPN
fnp-2971	64	8	are	be	AUX
fnp-2971	64	9	considered	consider	VERB
fnp-2971	64	10	the	the	DET
fnp-2971	64	11	most	most	ADV
fnp-2971	64	12	sensitive	sensitive	ADJ
fnp-2971	64	13	markers	marker	NOUN
fnp-2971	64	14	for	for	ADP
fnp-2971	64	15	microglia	microglia	NOUN
fnp-2971	64	16	as	as	SCONJ
fnp-2971	64	17	both	both	DET
fnp-2971	64	18	stain	stain	NOUN
fnp-2971	64	19	all	all	DET
fnp-2971	64	20	the	the	DET
fnp-2971	64	21	morphological	morphological	ADJ
fnp-2971	64	22	forms	form	NOUN
fnp-2971	64	23	of	of	ADP
fnp-2971	64	24	activated	activated	ADJ
fnp-2971	64	25	microglia	microglia	ADJ
fnp-2971	64	26	,	,	PUNCT
fnp-2971	64	27	phagocytic	phagocytic	ADJ
fnp-2971	64	28	,	,	PUNCT
fnp-2971	64	29	and	and	CCONJ
fnp-2971	64	30	dystrophic	dystrophic	ADJ
fnp-2971	64	31	microglia	microglia	NOUN
fnp-2971	64	32	(	(	PUNCT
fnp-2971	64	33	5	5	NUM
fnp-2971	64	34	)	)	PUNCT
fnp-2971	64	35	.	.	PUNCT
fnp-2971	65	1	although	although	SCONJ
fnp-2971	65	2	iba1	iba1	PROPN
fnp-2971	65	3	may	may	AUX
fnp-2971	65	4	be	be	AUX
fnp-2971	65	5	considered	consider	VERB
fnp-2971	65	6	to	to	PART
fnp-2971	65	7	be	be	AUX
fnp-2971	65	8	a	a	DET
fnp-2971	65	9	more	more	ADV
fnp-2971	65	10	sensitive	sensitive	ADJ
fnp-2971	65	11	marker	marker	NOUN
fnp-2971	65	12	for	for	ADP
fnp-2971	65	13	these	these	DET
fnp-2971	65	14	microglia	microglia	NOUN
fnp-2971	65	15	by	by	ADP
fnp-2971	65	16	some	some	DET
fnp-2971	65	17	authors	author	NOUN
fnp-2971	65	18	(	(	PUNCT
fnp-2971	65	19	5	5	NUM
fnp-2971	65	20	)	)	PUNCT
fnp-2971	65	21	,	,	PUNCT
fnp-2971	65	22	we	we	PRON
fnp-2971	65	23	found	find	VERB
fnp-2971	65	24	that	that	SCONJ
fnp-2971	65	25	hla	hla	PROPN
fnp-2971	65	26	-	-	PUNCT
fnp-2971	65	27	dr	dr	PROPN
fnp-2971	65	28	is	be	AUX
fnp-2971	65	29	more	more	ADV
fnp-2971	65	30	sensitive	sensitive	ADJ
fnp-2971	65	31	for	for	ADP
fnp-2971	65	32	microglia	microglia	NOUN
fnp-2971	65	33	staining	stain	VERB
fnp-2971	65	34	in	in	ADP
fnp-2971	65	35	the	the	DET
fnp-2971	65	36	white	white	ADJ
fnp-2971	65	37	matter	matter	NOUN
fnp-2971	65	38	and	and	CCONJ
fnp-2971	65	39	comparable	comparable	ADJ
fnp-2971	65	40	to	to	ADP
fnp-2971	65	41	iba1	iba1	PROPN
fnp-2971	65	42	staining	stain	VERB
fnp-2971	65	43	in	in	ADP
fnp-2971	65	44	the	the	DET
fnp-2971	65	45	gray	gray	ADJ
fnp-2971	65	46	matter	matter	NOUN
fnp-2971	65	47	.	.	PUNCT
fnp-2971	66	1	iba1	iba1	PROPN
fnp-2971	66	2	immunostaining	immunostaining	NOUN
fnp-2971	66	3	also	also	ADV
fnp-2971	66	4	showed	show	VERB
fnp-2971	66	5	background	background	NOUN
fnp-2971	66	6	staining	stain	VERB
fnp-2971	66	7	,	,	PUNCT
fnp-2971	66	8	requiring	require	VERB
fnp-2971	66	9	careful	careful	ADJ
fnp-2971	66	10	examination	examination	NOUN
fnp-2971	66	11	to	to	PART
fnp-2971	66	12	distinguish	distinguish	VERB
fnp-2971	66	13	the	the	DET
fnp-2971	66	14	immunopositive	immunopositive	ADJ
fnp-2971	66	15	cells	cell	NOUN
fnp-2971	66	16	from	from	ADP
fnp-2971	66	17	the	the	DET
fnp-2971	66	18	background	background	NOUN
fnp-2971	66	19	(	(	PUNCT
fnp-2971	66	20	see	see	VERB
fnp-2971	66	21	supplemental	supplemental	ADJ
fnp-2971	66	22	figure	figure	NOUN
fnp-2971	66	23	2	2	NUM
fnp-2971	66	24	)	)	PUNCT
fnp-2971	66	25	.	.	PUNCT
fnp-2971	67	1	this	this	PRON
fnp-2971	67	2	resulted	result	VERB
fnp-2971	67	3	in	in	ADP
fnp-2971	67	4	an	an	DET
fnp-2971	67	5	inferior	inferior	ADJ
fnp-2971	67	6	quality	quality	NOUN
fnp-2971	67	7	of	of	ADP
fnp-2971	67	8	images	image	NOUN
fnp-2971	67	9	for	for	ADP
fnp-2971	67	10	analysis	analysis	NOUN
fnp-2971	67	11	.	.	PUNCT
fnp-2971	68	1	the	the	DET
fnp-2971	68	2	following	follow	VERB
fnp-2971	68	3	results	result	NOUN
fnp-2971	68	4	were	be	AUX
fnp-2971	68	5	confirmed	confirm	VERB
fnp-2971	68	6	by	by	ADP
fnp-2971	68	7	both	both	PRON
fnp-2971	68	8	hla	hla	PROPN
fnp-2971	68	9	-	-	PUNCT
fnp-2971	68	10	dr	dr	PROPN
fnp-2971	68	11	and	and	CCONJ
fnp-2971	68	12	iba1	iba1	PROPN
fnp-2971	68	13	immunostains	immunostain	NOUN
fnp-2971	68	14	but	but	CCONJ
fnp-2971	68	15	are	be	AUX
fnp-2971	68	16	better	well	ADV
fnp-2971	68	17	demonstrated	demonstrate	VERB
fnp-2971	68	18	with	with	ADP
fnp-2971	68	19	the	the	DET
fnp-2971	68	20	hla	hla	PROPN
fnp-2971	68	21	-	-	PUNCT
fnp-2971	68	22	dr	dr	PROPN
fnp-2971	68	23	images	image	NOUN
fnp-2971	68	24	,	,	PUNCT
fnp-2971	68	25	which	which	PRON
fnp-2971	68	26	we	we	PRON
fnp-2971	68	27	will	will	AUX
fnp-2971	68	28	utilize	utilize	VERB
fnp-2971	68	29	in	in	ADP
fnp-2971	68	30	the	the	DET
fnp-2971	68	31	rest	rest	NOUN
fnp-2971	68	32	of	of	ADP
fnp-2971	68	33	this	this	DET
fnp-2971	68	34	article	article	NOUN
fnp-2971	68	35	.	.	PUNCT
fnp-2971	69	1	hla	hla	PROPN
fnp-2971	69	2	-	-	PUNCT
fnp-2971	69	3	dr	dr	PROPN
fnp-2971	69	4	and	and	CCONJ
fnp-2971	69	5	iba1	iba1	PROPN
fnp-2971	69	6	immunostaining	immunostaining	NOUN
fnp-2971	69	7	showed	show	VERB
fnp-2971	69	8	a	a	DET
fnp-2971	69	9	wide	wide	ADJ
fnp-2971	69	10	variation	variation	NOUN
fnp-2971	69	11	of	of	ADP
fnp-2971	69	12	microglial	microglial	ADJ
fnp-2971	69	13	morphology	morphology	NOUN
fnp-2971	69	14	in	in	ADP
fnp-2971	69	15	both	both	CCONJ
fnp-2971	69	16	gray	gray	ADJ
fnp-2971	69	17	and	and	CCONJ
fnp-2971	69	18	white	white	ADJ
fnp-2971	69	19	matter	matter	NOUN
fnp-2971	69	20	in	in	ADP
fnp-2971	69	21	all	all	DET
fnp-2971	69	22	cases	case	NOUN
fnp-2971	69	23	.	.	PUNCT
fnp-2971	70	1	microglial	microglial	ADJ
fnp-2971	70	2	processes	process	NOUN
fnp-2971	70	3	showed	show	VERB
fnp-2971	70	4	variations	variation	NOUN
fnp-2971	70	5	in	in	ADP
fnp-2971	70	6	number	number	NOUN
fnp-2971	70	7	(	(	PUNCT
fnp-2971	70	8	single	single	ADJ
fnp-2971	70	9	to	to	ADP
fnp-2971	70	10	multiple	multiple	ADJ
fnp-2971	70	11	)	)	PUNCT
fnp-2971	70	12	,	,	PUNCT
fnp-2971	70	13	thickness	thickness	NOUN
fnp-2971	70	14	,	,	PUNCT
fnp-2971	70	15	and	and	CCONJ
fnp-2971	70	16	length	length	NOUN
fnp-2971	70	17	.	.	PUNCT
fnp-2971	71	1	some	some	PRON
fnp-2971	71	2	of	of	ADP
fnp-2971	71	3	the	the	DET
fnp-2971	71	4	processes	process	NOUN
fnp-2971	71	5	showed	show	VERB
fnp-2971	71	6	discontinuous	discontinuous	ADJ
fnp-2971	71	7	staining	staining	NOUN
fnp-2971	71	8	and	and	CCONJ
fnp-2971	71	9	some	some	DET
fnp-2971	71	10	areas	area	NOUN
fnp-2971	71	11	showed	show	VERB
fnp-2971	71	12	only	only	ADV
fnp-2971	71	13	fragmented	fragmented	ADJ
fnp-2971	71	14	processes	process	NOUN
fnp-2971	71	15	,	,	PUNCT
fnp-2971	71	16	which	which	PRON
fnp-2971	71	17	could	could	AUX
fnp-2971	71	18	be	be	AUX
fnp-2971	71	19	considered	consider	VERB
fnp-2971	71	20	dysplastic	dysplastic	ADJ
fnp-2971	71	21	(	(	PUNCT
fnp-2971	71	22	4	4	NUM
fnp-2971	71	23	)	)	PUNCT
fnp-2971	71	24	or	or	CCONJ
fnp-2971	71	25	dystrophic	dystrophic	ADJ
fnp-2971	71	26	(	(	PUNCT
fnp-2971	71	27	5	5	NUM
fnp-2971	71	28	)	)	PUNCT
fnp-2971	71	29	.	.	PUNCT
fnp-2971	72	1	microglia	microglia	ADJ
fnp-2971	72	2	with	with	ADP
fnp-2971	72	3	fragmented	fragmented	ADJ
fnp-2971	72	4	processes	process	NOUN
fnp-2971	72	5	were	be	AUX
fnp-2971	72	6	observed	observe	VERB
fnp-2971	72	7	along	along	ADP
fnp-2971	72	8	with	with	ADP
fnp-2971	72	9	those	those	PRON
fnp-2971	72	10	with	with	ADP
fnp-2971	72	11	intact	intact	ADJ
fnp-2971	72	12	processes	process	NOUN
fnp-2971	72	13	in	in	ADP
fnp-2971	72	14	areas	area	NOUN
fnp-2971	72	15	of	of	ADP
fnp-2971	72	16	normal	normal	ADJ
fnp-2971	72	17	-	-	PUNCT
fnp-2971	72	18	appearing	appear	VERB
fnp-2971	72	19	white	white	ADJ
fnp-2971	72	20	matter	matter	NOUN
fnp-2971	72	21	.	.	PUNCT
fnp-2971	73	1	this	this	DET
fnp-2971	73	2	wide	wide	ADJ
fnp-2971	73	3	morphological	morphological	ADJ
fnp-2971	73	4	variation	variation	NOUN
fnp-2971	73	5	made	make	VERB
fnp-2971	73	6	it	it	PRON
fnp-2971	73	7	difficult	difficult	ADJ
fnp-2971	73	8	to	to	PART
fnp-2971	73	9	correlate	correlate	VERB
fnp-2971	73	10	between	between	ADP
fnp-2971	73	11	microglial	microglial	ADJ
fnp-2971	73	12	morphology	morphology	NOUN
fnp-2971	73	13	and	and	CCONJ
fnp-2971	73	14	axonal	axonal	ADJ
fnp-2971	73	15	spheroids	spheroid	NOUN
fnp-2971	73	16	.	.	PUNCT
fnp-2971	74	1	therefore	therefore	ADV
fnp-2971	74	2	,	,	PUNCT
fnp-2971	74	3	as	as	SCONJ
fnp-2971	74	4	indicated	indicate	VERB
fnp-2971	74	5	in	in	ADP
fnp-2971	74	6	materials	material	NOUN
fnp-2971	74	7	and	and	CCONJ
fnp-2971	74	8	methods	method	NOUN
fnp-2971	74	9	,	,	PUNCT
fnp-2971	74	10	we	we	PRON
fnp-2971	74	11	only	only	ADV
fnp-2971	74	12	considered	consider	VERB
fnp-2971	74	13	microglia	microglia	ADJ
fnp-2971	74	14	with	with	ADP
fnp-2971	74	15	the	the	DET
fnp-2971	74	16	amoeboid	amoeboid	ADJ
fnp-2971	74	17	phenotype	phenotype	NOUN
fnp-2971	74	18	(	(	PUNCT
fnp-2971	74	19	i.e.	i.e.	X
fnp-2971	74	20	globular	globular	ADJ
fnp-2971	74	21	cytoplasm	cytoplasm	NOUN
fnp-2971	74	22	with	with	ADP
fnp-2971	74	23	no	no	DET
fnp-2971	74	24	processes	process	NOUN
fnp-2971	74	25	)	)	PUNCT
fnp-2971	74	26	as	as	ADP
fnp-2971	74	27	a	a	DET
fnp-2971	74	28	separate	separate	ADJ
fnp-2971	74	29	form	form	NOUN
fnp-2971	74	30	of	of	ADP
fnp-2971	74	31	microglia	microglia	NOUN
fnp-2971	74	32	.	.	PUNCT
fnp-2971	75	1	all	all	DET
fnp-2971	75	2	other	other	ADJ
fnp-2971	75	3	morphological	morphological	ADJ
fnp-2971	75	4	variations	variation	NOUN
fnp-2971	75	5	of	of	ADP
fnp-2971	75	6	microglia	microglia	NOUN
fnp-2971	75	7	,	,	PUNCT
fnp-2971	75	8	including	include	VERB
fnp-2971	75	9	those	those	PRON
fnp-2971	75	10	with	with	ADP
fnp-2971	75	11	fragmented	fragmented	ADJ
fnp-2971	75	12	processes	process	NOUN
fnp-2971	75	13	,	,	PUNCT
fnp-2971	75	14	were	be	AUX
fnp-2971	75	15	considered	consider	VERB
fnp-2971	75	16	ramified	ramified	ADJ
fnp-2971	75	17	/	/	SYM
fnp-2971	75	18	reactive	reactive	ADJ
fnp-2971	75	19	microglia	microglia	NOUN
fnp-2971	75	20	.	.	PUNCT
fnp-2971	76	1	using	use	VERB
fnp-2971	76	2	this	this	DET
fnp-2971	76	3	simplified	simplified	ADJ
fnp-2971	76	4	categorization	categorization	NOUN
fnp-2971	76	5	of	of	ADP
fnp-2971	76	6	hla	hla	PROPN
fnp-2971	76	7	-	-	PUNCT
fnp-2971	76	8	dr	dr	PROPN
fnp-2971	76	9	and	and	CCONJ
fnp-2971	76	10	iba1	iba1	NOUN
fnp-2971	76	11	-	-	PUNCT
fnp-2971	76	12	expressing	express	VERB
fnp-2971	76	13	cells	cell	NOUN
fnp-2971	76	14	(	(	PUNCT
fnp-2971	76	15	ramified	ramify	VERB
fnp-2971	76	16	vs.	vs.	ADP
fnp-2971	76	17	amoeboid	amoeboid	ADJ
fnp-2971	76	18	phenotype	phenotype	NOUN
fnp-2971	76	19	)	)	PUNCT
fnp-2971	76	20	,	,	PUNCT
fnp-2971	76	21	we	we	PRON
fnp-2971	76	22	consistently	consistently	ADV
fnp-2971	76	23	detected	detect	VERB
fnp-2971	76	24	the	the	DET
fnp-2971	76	25	following	follow	VERB
fnp-2971	76	26	changes	change	NOUN
fnp-2971	76	27	in	in	ADP
fnp-2971	76	28	all	all	DET
fnp-2971	76	29	6	6	NUM
fnp-2971	76	30	cases	case	NOUN
fnp-2971	76	31	(	(	PUNCT
fnp-2971	76	32	table	table	NOUN
fnp-2971	76	33	2	2	NUM
fnp-2971	76	34	):	):	PUNCT
fnp-2971	76	35	the	the	DET
fnp-2971	76	36	white	white	ADJ
fnp-2971	76	37	matter	matter	NOUN
fnp-2971	76	38	lesions	lesion	NOUN
fnp-2971	76	39	classified	classify	VERB
fnp-2971	76	40	as	as	ADP
fnp-2971	76	41	stage	stage	NOUN
fnp-2971	76	42	1	1	NUM
fnp-2971	76	43	pathology	pathology	NOUN
fnp-2971	76	44	showed	show	VERB
fnp-2971	76	45	well	well	ADV
fnp-2971	76	46	-	-	PUNCT
fnp-2971	76	47	myelinated	myelinate	VERB
fnp-2971	76	48	areas	area	NOUN
fnp-2971	76	49	with	with	ADP
fnp-2971	76	50	moderate	moderate	ADJ
fnp-2971	76	51	to	to	PART
fnp-2971	76	52	frequent	frequent	ADJ
fnp-2971	76	53	(	(	PUNCT
fnp-2971	76	54	score	score	NOUN
fnp-2971	76	55	2–3	2–3	NOUN
fnp-2971	76	56	)	)	PUNCT
fnp-2971	76	57	axonal	axonal	ADJ
fnp-2971	76	58	spheroids	spheroid	NOUN
fnp-2971	76	59	and	and	CCONJ
fnp-2971	76	60	a	a	DET
fnp-2971	76	61	consistent	consistent	ADJ
fnp-2971	76	62	loss	loss	NOUN
fnp-2971	76	63	of	of	ADP
fnp-2971	76	64	hla	hla	PROPN
fnp-2971	76	65	-	-	PUNCT
fnp-2971	76	66	dr	dr	NOUN
fnp-2971	76	67	-	-	PUNCT
fnp-2971	76	68	expressing	express	VERB
fnp-2971	76	69	cells	cell	NOUN
fnp-2971	76	70	with	with	ADP
fnp-2971	76	71	ramified	ramified	ADJ
fnp-2971	76	72	morphology	morphology	NOUN
fnp-2971	76	73	(	(	PUNCT
fnp-2971	76	74	score	score	NOUN
fnp-2971	76	75	0	0	NUM
fnp-2971	76	76	)	)	PUNCT
fnp-2971	76	77	in	in	ADP
fnp-2971	76	78	close	close	ADJ
fnp-2971	76	79	proximity	proximity	NOUN
fnp-2971	76	80	to	to	ADP
fnp-2971	76	81	the	the	DET
fnp-2971	76	82	axonal	axonal	ADJ
fnp-2971	76	83	spheroids	spheroid	NOUN
fnp-2971	76	84	(	(	PUNCT
fnp-2971	76	85	figure	figure	NOUN
fnp-2971	76	86	1a	1a	NOUN
fnp-2971	76	87	–	–	PUNCT
fnp-2971	76	88	f	f	X
fnp-2971	76	89	)	)	PUNCT
fnp-2971	76	90	.	.	PUNCT
fnp-2971	77	1	some	some	DET
fnp-2971	77	2	areas	area	NOUN
fnp-2971	77	3	had	have	VERB
fnp-2971	77	4	a	a	DET
fnp-2971	77	5	few	few	ADJ
fnp-2971	77	6	(	(	PUNCT
fnp-2971	77	7	score	score	NOUN
fnp-2971	77	8	1	1	NUM
fnp-2971	77	9	)	)	PUNCT
fnp-2971	77	10	hla	hla	PROPN
fnp-2971	77	11	-	-	PUNCT
fnp-2971	77	12	dr	dr	NOUN
fnp-2971	77	13	-	-	PUNCT
fnp-2971	77	14	expressing	express	VERB
fnp-2971	77	15	microglia	microglia	NOUN
fnp-2971	77	16	with	with	ADP
fnp-2971	77	17	amoeboid	amoeboid	ADJ
fnp-2971	77	18	phenotype	phenotype	NOUN
fnp-2971	77	19	,	,	PUNCT
fnp-2971	77	20	while	while	SCONJ
fnp-2971	77	21	others	other	NOUN
fnp-2971	77	22	showed	show	VERB
fnp-2971	77	23	none	none	NOUN
fnp-2971	77	24	(	(	PUNCT
fnp-2971	77	25	score	score	NOUN
fnp-2971	77	26	0	0	NUM
fnp-2971	77	27	)	)	PUNCT
fnp-2971	77	28	.	.	PUNCT
fnp-2971	78	1	this	this	PRON
fnp-2971	78	2	may	may	AUX
fnp-2971	78	3	indicate	indicate	VERB
fnp-2971	78	4	that	that	SCONJ
fnp-2971	78	5	these	these	DET
fnp-2971	78	6	areas	area	NOUN
fnp-2971	78	7	had	have	VERB
fnp-2971	78	8	a	a	DET
fnp-2971	78	9	slightly	slightly	ADV
fnp-2971	78	10	longer	long	ADJ
fnp-2971	78	11	pathology	pathology	NOUN
fnp-2971	78	12	duration	duration	NOUN
fnp-2971	78	13	than	than	ADP
fnp-2971	78	14	the	the	DET
fnp-2971	78	15	areas	area	NOUN
fnp-2971	78	16	without	without	ADP
fnp-2971	78	17	these	these	DET
fnp-2971	78	18	cells	cell	NOUN
fnp-2971	78	19	.	.	PUNCT
fnp-2971	79	1	the	the	DET
fnp-2971	79	2	white	white	ADJ
fnp-2971	79	3	matter	matter	NOUN
fnp-2971	79	4	adjacent	adjacent	ADJ
fnp-2971	79	5	to	to	ADP
fnp-2971	79	6	the	the	DET
fnp-2971	79	7	affected	affect	VERB
fnp-2971	79	8	areas	area	NOUN
fnp-2971	79	9	was	be	AUX
fnp-2971	79	10	unremarkable	unremarkable	ADJ
fnp-2971	79	11	,	,	PUNCT
fnp-2971	79	12	with	with	ADP
fnp-2971	79	13	no	no	DET
fnp-2971	79	14	axonal	axonal	ADJ
fnp-2971	79	15	spheroids	spheroid	NOUN
fnp-2971	79	16	,	,	PUNCT
fnp-2971	79	17	no	no	DET
fnp-2971	79	18	pigmented	pigmented	ADJ
fnp-2971	79	19	microglia	microglia	NOUN
fnp-2971	79	20	,	,	PUNCT
fnp-2971	79	21	or	or	CCONJ
fnp-2971	79	22	other	other	ADJ
fnp-2971	79	23	abnormality	abnormality	NOUN
fnp-2971	79	24	(	(	PUNCT
fnp-2971	79	25	figure	figure	NOUN
fnp-2971	79	26	1	1	NUM
fnp-2971	79	27	g	g	NOUN
fnp-2971	79	28	)	)	PUNCT
fnp-2971	79	29	.	.	PUNCT
fnp-2971	80	1	however	however	ADV
fnp-2971	80	2	,	,	PUNCT
fnp-2971	80	3	hla	hla	PROPN
fnp-2971	80	4	-	-	PUNCT
fnp-2971	80	5	dr	dr	PROPN
fnp-2971	80	6	immunostaining	immunostaining	NOUN
fnp-2971	80	7	showed	show	VERB
fnp-2971	80	8	denser	dense	ADJ
fnp-2971	80	9	forms	form	NOUN
fnp-2971	80	10	of	of	ADP
fnp-2971	80	11	“	"	PUNCT
fnp-2971	80	12	ramified	ramified	ADJ
fnp-2971	80	13	”	"	PUNCT
fnp-2971	80	14	microglia	microglia	NOUN
fnp-2971	80	15	(	(	PUNCT
fnp-2971	80	16	figure	figure	NOUN
fnp-2971	80	17	1h	1h	NUM
fnp-2971	80	18	)	)	PUNCT
fnp-2971	80	19	.	.	PUNCT
fnp-2971	81	1	the	the	DET
fnp-2971	81	2	remarkable	remarkable	ADJ
fnp-2971	81	3	association	association	NOUN
fnp-2971	81	4	of	of	ADP
fnp-2971	81	5	axonal	axonal	ADJ
fnp-2971	81	6	spheroids	spheroid	NOUN
fnp-2971	81	7	and	and	CCONJ
fnp-2971	81	8	the	the	DET
fnp-2971	81	9	complete	complete	ADJ
fnp-2971	81	10	loss	loss	NOUN
fnp-2971	81	11	of	of	ADP
fnp-2971	81	12	ramified	ramified	ADJ
fnp-2971	81	13	microglia	microglia	NOUN
fnp-2971	81	14	was	be	AUX
fnp-2971	81	15	also	also	ADV
fnp-2971	81	16	evident	evident	ADJ
fnp-2971	81	17	in	in	ADP
fnp-2971	81	18	the	the	DET
fnp-2971	81	19	affected	affected	ADJ
fnp-2971	81	20	cortex	cortex	NOUN
fnp-2971	81	21	(	(	PUNCT
fnp-2971	81	22	figure	figure	NOUN
fnp-2971	81	23	2a	2a	NUM
fnp-2971	81	24	–	–	PUNCT
fnp-2971	81	25	d	d	NOUN
fnp-2971	81	26	)	)	PUNCT
fnp-2971	81	27	.	.	PUNCT
fnp-2971	82	1	this	this	DET
fnp-2971	82	2	association	association	NOUN
fnp-2971	82	3	was	be	AUX
fnp-2971	82	4	apparent	apparent	ADJ
fnp-2971	82	5	even	even	ADV
fnp-2971	82	6	in	in	ADP
fnp-2971	82	7	a	a	DET
fnp-2971	82	8	very	very	ADV
fnp-2971	82	9	small	small	ADJ
fnp-2971	82	10	area	area	NOUN
fnp-2971	82	11	of	of	ADP
fnp-2971	82	12	cortical	cortical	ADJ
fnp-2971	82	13	involvement	involvement	NOUN
fnp-2971	82	14	,	,	PUNCT
fnp-2971	82	15	while	while	SCONJ
fnp-2971	82	16	the	the	DET
fnp-2971	82	17	immediately	immediately	ADV
fnp-2971	82	18	adjacent	adjacent	ADJ
fnp-2971	82	19	area	area	NOUN
fnp-2971	82	20	showed	show	VERB
fnp-2971	82	21	ramified	ramified	ADJ
fnp-2971	82	22	microglia	microglia	NOUN
fnp-2971	82	23	(	(	PUNCT
fnp-2971	82	24	figure	figure	NOUN
fnp-2971	82	25	2e	2e	NUM
fnp-2971	82	26	–	–	PUNCT
fnp-2971	82	27	h	h	NOUN
fnp-2971	82	28	)	)	PUNCT
fnp-2971	82	29	.	.	PUNCT
fnp-2971	83	1	in	in	ADP
fnp-2971	83	2	stage	stage	NOUN
fnp-2971	83	3	2	2	NUM
fnp-2971	83	4	pathology	pathology	NOUN
fnp-2971	83	5	,	,	PUNCT
fnp-2971	83	6	white	white	ADJ
fnp-2971	83	7	matter	matter	NOUN
fnp-2971	83	8	showed	show	VERB
fnp-2971	83	9	reduced	reduce	VERB
fnp-2971	83	10	myelin	myelin	NOUN
fnp-2971	83	11	staining	stain	VERB
fnp-2971	83	12	(	(	PUNCT
fnp-2971	83	13	figure	figure	NOUN
fnp-2971	83	14	3a	3a	NUM
fnp-2971	83	15	–	–	PUNCT
fnp-2971	83	16	b	b	NOUN
fnp-2971	83	17	)	)	PUNCT
fnp-2971	83	18	,	,	PUNCT
fnp-2971	83	19	a	a	DET
fnp-2971	83	20	variable	variable	ADJ
fnp-2971	83	21	number	number	NOUN
fnp-2971	83	22	of	of	ADP
fnp-2971	83	23	axonal	axonal	ADJ
fnp-2971	83	24	spheroids	spheroid	NOUN
fnp-2971	83	25	ranging	range	VERB
fnp-2971	83	26	from	from	ADP
fnp-2971	83	27	none	none	NOUN
fnp-2971	83	28	to	to	ADP
fnp-2971	83	29	frequent	frequent	ADJ
fnp-2971	83	30	(	(	PUNCT
fnp-2971	83	31	score	score	NOUN
fnp-2971	83	32	0–3	0–3	PROPN
fnp-2971	83	33	)	)	PUNCT
fnp-2971	83	34	,	,	PUNCT
fnp-2971	83	35	moderate	moderate	ADJ
fnp-2971	83	36	to	to	ADP
fnp-2971	83	37	frequent	frequent	ADJ
fnp-2971	83	38	amoeboid	amoeboid	ADJ
fnp-2971	83	39	microglia	microglia	NOUN
fnp-2971	83	40	(	(	PUNCT
fnp-2971	83	41	score	score	NOUN
fnp-2971	83	42	2–3	2–3	NUM
fnp-2971	83	43	)	)	PUNCT
fnp-2971	83	44	,	,	PUNCT
fnp-2971	83	45	and	and	CCONJ
fnp-2971	83	46	none	none	NOUN
fnp-2971	83	47	to	to	ADP
fnp-2971	83	48	few	few	ADJ
fnp-2971	83	49	ramified	ramified	ADJ
fnp-2971	83	50	microglia	microglia	NOUN
fnp-2971	83	51	.	.	PUNCT
fnp-2971	84	1	according	accord	VERB
fnp-2971	84	2	to	to	ADP
fnp-2971	84	3	the	the	DET
fnp-2971	84	4	distribution	distribution	NOUN
fnp-2971	84	5	of	of	ADP
fnp-2971	84	6	axonal	axonal	ADJ
fnp-2971	84	7	spheroids	spheroid	NOUN
fnp-2971	84	8	,	,	PUNCT
fnp-2971	84	9	these	these	DET
fnp-2971	84	10	areas	area	NOUN
fnp-2971	84	11	were	be	AUX
fnp-2971	84	12	subclassified	subclassifie	VERB
fnp-2971	84	13	into	into	ADP
fnp-2971	84	14	three	three	NUM
fnp-2971	84	15	components	component	NOUN
fnp-2971	84	16	:	:	PUNCT
fnp-2971	84	17	1	1	NUM
fnp-2971	84	18	)	)	PUNCT
fnp-2971	84	19	areas	area	NOUN
fnp-2971	84	20	with	with	ADP
fnp-2971	84	21	axonal	axonal	ADJ
fnp-2971	84	22	spheroids	spheroid	NOUN
fnp-2971	84	23	(	(	PUNCT
fnp-2971	84	24	score	score	NOUN
fnp-2971	84	25	1–3	1–3	NUM
fnp-2971	84	26	)	)	PUNCT
fnp-2971	84	27	,	,	PUNCT
fnp-2971	84	28	showing	show	VERB
fnp-2971	84	29	no	no	DET
fnp-2971	84	30	ramified	ramified	ADJ
fnp-2971	84	31	microglia	microglia	NOUN
fnp-2971	84	32	(	(	PUNCT
fnp-2971	84	33	score	score	NOUN
fnp-2971	84	34	0	0	NUM
fnp-2971	84	35	)	)	PUNCT
fnp-2971	84	36	,	,	PUNCT
fnp-2971	84	37	but	but	CCONJ
fnp-2971	84	38	moderate	moderate	ADJ
fnp-2971	84	39	to	to	ADP
fnp-2971	84	40	frequent	frequent	ADJ
fnp-2971	84	41	amoeboid	amoeboid	ADJ
fnp-2971	84	42	microglia	microglia	NOUN
fnp-2971	84	43	(	(	PUNCT
fnp-2971	84	44	score	score	NOUN
fnp-2971	84	45	2–3	2–3	NUM
fnp-2971	84	46	)	)	PUNCT
fnp-2971	84	47	.	.	PUNCT
fnp-2971	85	1	these	these	DET
fnp-2971	85	2	areas	area	NOUN
fnp-2971	85	3	may	may	AUX
fnp-2971	85	4	represent	represent	VERB
fnp-2971	85	5	an	an	DET
fnp-2971	85	6	“	"	PUNCT
fnp-2971	85	7	active	active	ADJ
fnp-2971	85	8	/	/	SYM
fnp-2971	85	9	ongoing	ongoing	ADJ
fnp-2971	85	10	injury	injury	NOUN
fnp-2971	85	11	.	.	PUNCT
fnp-2971	85	12	”	"	PUNCT
fnp-2971	86	1	the	the	DET
fnp-2971	86	2	white	white	ADJ
fnp-2971	86	3	matter	matter	NOUN
fnp-2971	86	4	surrounding	surround	VERB
fnp-2971	86	5	these	these	DET
fnp-2971	86	6	areas	area	NOUN
fnp-2971	86	7	showed	show	VERB
fnp-2971	86	8	widespread	widespread	ADJ
fnp-2971	86	9	dense	dense	ADJ
fnp-2971	86	10	ramified	ramified	ADJ
fnp-2971	86	11	microglia	microglia	NOUN
fnp-2971	86	12	(	(	PUNCT
fnp-2971	86	13	score	score	NOUN
fnp-2971	86	14	3	3	NUM
fnp-2971	86	15	)	)	PUNCT
fnp-2971	86	16	,	,	PUNCT
fnp-2971	86	17	while	while	SCONJ
fnp-2971	86	18	cells	cell	NOUN
fnp-2971	86	19	with	with	ADP
fnp-2971	86	20	amoeboid	amoeboid	NOUN
fnp-2971	86	21	-	-	PUNCT
fnp-2971	86	22	phenotype	phenotype	NOUN
fnp-2971	86	23	were	be	AUX
fnp-2971	86	24	present	present	ADJ
fnp-2971	86	25	in	in	ADP
fnp-2971	86	26	the	the	DET
fnp-2971	86	27	central	central	ADJ
fnp-2971	86	28	area	area	NOUN
fnp-2971	86	29	(	(	PUNCT
fnp-2971	86	30	score	score	NOUN
fnp-2971	86	31	2–3	2–3	NUM
fnp-2971	86	32	)	)	PUNCT
fnp-2971	86	33	,	,	PUNCT
fnp-2971	86	34	and	and	CCONJ
fnp-2971	86	35	the	the	DET
fnp-2971	86	36	surrounding	surround	VERB
fnp-2971	86	37	white	white	ADJ
fnp-2971	86	38	matter	matter	NOUN
fnp-2971	86	39	(	(	PUNCT
fnp-2971	86	40	figure	figure	VERB
fnp-2971	86	41	3c	3c	NUM
fnp-2971	86	42	–	–	PUNCT
fnp-2971	86	43	f	f	NOUN
fnp-2971	86	44	)	)	PUNCT
fnp-2971	86	45	,	,	PUNCT
fnp-2971	86	46	used	use	VERB
fnp-2971	86	47	as	as	ADP
fnp-2971	86	48	an	an	DET
fnp-2971	86	49	internal	internal	ADJ
fnp-2971	86	50	control	control	NOUN
fnp-2971	86	51	for	for	ADP
fnp-2971	86	52	hla	hla	PROPN
fnp-2971	86	53	-	-	PUNCT
fnp-2971	86	54	dr	dr	PROPN
fnp-2971	86	55	immunostaining	immunostaining	NOUN
fnp-2971	86	56	.	.	PUNCT
fnp-2971	87	1	2	2	X
fnp-2971	87	2	)	)	PUNCT
fnp-2971	87	3	areas	area	NOUN
fnp-2971	87	4	with	with	ADP
fnp-2971	87	5	no	no	DET
fnp-2971	87	6	axonal	axonal	ADJ
fnp-2971	87	7	spheroids	spheroid	NOUN
fnp-2971	87	8	(	(	PUNCT
fnp-2971	87	9	score	score	NOUN
fnp-2971	87	10	0	0	NUM
fnp-2971	87	11	)	)	PUNCT
fnp-2971	87	12	,	,	PUNCT
fnp-2971	87	13	few	few	ADJ
fnp-2971	87	14	-	-	PUNCT
fnp-2971	87	15	moderate	moderate	ADJ
fnp-2971	87	16	amoeboid	amoeboid	ADJ
fnp-2971	87	17	microglia	microglia	NOUN
fnp-2971	87	18	(	(	PUNCT
fnp-2971	87	19	score	score	NOUN
fnp-2971	87	20	1–2	1–2	NUM
fnp-2971	87	21	)	)	PUNCT
fnp-2971	87	22	,	,	PUNCT
fnp-2971	87	23	and	and	CCONJ
fnp-2971	87	24	no	no	DET
fnp-2971	87	25	ramified	ramified	ADJ
fnp-2971	87	26	microglia	microglia	NOUN
fnp-2971	87	27	(	(	PUNCT
fnp-2971	87	28	score	score	NOUN
fnp-2971	87	29	0	0	NUM
fnp-2971	87	30	;	;	PUNCT
fnp-2971	87	31	figure	figure	NOUN
fnp-2971	87	32	3g	3g	NOUN
fnp-2971	87	33	–	–	PUNCT
fnp-2971	87	34	h	h	NOUN
fnp-2971	87	35	)	)	PUNCT
fnp-2971	87	36	.	.	PUNCT
fnp-2971	88	1	these	these	PRON
fnp-2971	88	2	can	can	AUX
fnp-2971	88	3	be	be	AUX
fnp-2971	88	4	considered	consider	VERB
fnp-2971	88	5	“	"	PUNCT
fnp-2971	88	6	susceptible	susceptible	ADJ
fnp-2971	88	7	areas	area	NOUN
fnp-2971	88	8	”	"	PUNCT
fnp-2971	88	9	and	and	CCONJ
fnp-2971	88	10	can	can	AUX
fnp-2971	88	11	have	have	VERB
fnp-2971	88	12	a	a	DET
fnp-2971	88	13	different	different	ADJ
fnp-2971	88	14	degree	degree	NOUN
fnp-2971	88	15	of	of	ADP
fnp-2971	88	16	myelinated	myelinated	ADJ
fnp-2971	88	17	axons	axon	NOUN
fnp-2971	88	18	loss	loss	NOUN
fnp-2971	88	19	.	.	PUNCT
fnp-2971	89	1	3	3	X
fnp-2971	89	2	)	)	PUNCT
fnp-2971	89	3	areas	area	NOUN
fnp-2971	89	4	with	with	ADP
fnp-2971	89	5	no	no	DET
fnp-2971	89	6	axonal	axonal	ADJ
fnp-2971	89	7	spheroids	spheroid	NOUN
fnp-2971	89	8	(	(	PUNCT
fnp-2971	89	9	score	score	NOUN
fnp-2971	89	10	0	0	NUM
fnp-2971	89	11	)	)	PUNCT
fnp-2971	89	12	,	,	PUNCT
fnp-2971	89	13	few	few	ADJ
fnp-2971	89	14	-	-	PUNCT
fnp-2971	89	15	moderate	moderate	ADJ
fnp-2971	89	16	amoeboid	amoeboid	ADJ
fnp-2971	89	17	microglia	microglia	NOUN
fnp-2971	89	18	(	(	PUNCT
fnp-2971	89	19	score	score	NOUN
fnp-2971	89	20	1–2	1–2	NUM
fnp-2971	89	21	)	)	PUNCT
fnp-2971	89	22	,	,	PUNCT
fnp-2971	89	23	and	and	CCONJ
fnp-2971	89	24	none	none	NOUN
fnp-2971	89	25	to	to	ADP
fnp-2971	89	26	few	few	ADJ
fnp-2971	89	27	ramified	ramify	VERB
fnp-2971	89	28	microglial	microglial	ADJ
fnp-2971	89	29	cells	cell	NOUN
fnp-2971	89	30	(	(	PUNCT
fnp-2971	89	31	score	score	NOUN
fnp-2971	89	32	1	1	NUM
fnp-2971	89	33	)	)	PUNCT
fnp-2971	89	34	.	.	PUNCT
fnp-2971	90	1	these	these	PRON
fnp-2971	90	2	may	may	AUX
fnp-2971	90	3	represent	represent	VERB
fnp-2971	90	4	areas	area	NOUN
fnp-2971	90	5	of	of	ADP
fnp-2971	90	6	secondary	secondary	ADJ
fnp-2971	90	7	axonal	axonal	ADJ
fnp-2971	90	8	degeneration	degeneration	NOUN
fnp-2971	90	9	.	.	PUNCT
fnp-2971	91	1	figure	figure	NOUN
fnp-2971	91	2	1	1	NUM
fnp-2971	91	3	.	.	PUNCT
fnp-2971	92	1	microglia	microglia	ADJ
fnp-2971	92	2	and	and	CCONJ
fnp-2971	92	3	axonal	axonal	ADJ
fnp-2971	92	4	spheroids	spheroid	NOUN
fnp-2971	92	5	in	in	ADP
fnp-2971	92	6	stage	stage	NOUN
fnp-2971	92	7	1	1	NUM
fnp-2971	92	8	pathology	pathology	NOUN
fnp-2971	92	9	.	.	PUNCT
fnp-2971	93	1	(	(	PUNCT
fnp-2971	93	2	a	a	X
fnp-2971	93	3	)	)	PUNCT
fnp-2971	93	4	normal	normal	ADV
fnp-2971	93	5	-	-	PUNCT
fnp-2971	93	6	appearing	appear	VERB
fnp-2971	93	7	white	white	ADJ
fnp-2971	93	8	matter	matter	NOUN
fnp-2971	93	9	with	with	ADP
fnp-2971	93	10	frequent	frequent	ADJ
fnp-2971	93	11	spheroids	spheroid	NOUN
fnp-2971	93	12	inside	inside	ADP
fnp-2971	93	13	the	the	DET
fnp-2971	93	14	rectangular	rectangular	ADJ
fnp-2971	93	15	inset	inset	NOUN
fnp-2971	93	16	(	(	PUNCT
fnp-2971	93	17	lfb	lfb	PROPN
fnp-2971	93	18	-	-	PUNCT
fnp-2971	93	19	he	he	PRON
fnp-2971	93	20	;	;	PUNCT
fnp-2971	93	21	scale	scale	NOUN
fnp-2971	93	22	bar	bar	NOUN
fnp-2971	93	23	:	:	PUNCT
fnp-2971	93	24	500	500	NUM
fnp-2971	93	25	µm	µm	NUM
fnp-2971	93	26	)	)	PUNCT
fnp-2971	93	27	.	.	PUNCT
fnp-2971	94	1	(	(	PUNCT
fnp-2971	94	2	b	b	X
fnp-2971	94	3	)	)	PUNCT
fnp-2971	94	4	higher	high	ADJ
fnp-2971	94	5	magnification	magnification	NOUN
fnp-2971	94	6	of	of	ADP
fnp-2971	94	7	(	(	PUNCT
fnp-2971	94	8	a	a	PRON
fnp-2971	94	9	)	)	PUNCT
fnp-2971	94	10	shows	show	VERB
fnp-2971	94	11	many	many	ADJ
fnp-2971	94	12	spheroids	spheroid	NOUN
fnp-2971	94	13	and	and	CCONJ
fnp-2971	94	14	no	no	DET
fnp-2971	94	15	pigmented	pigmented	ADJ
fnp-2971	94	16	microglia	microglia	NOUN
fnp-2971	94	17	(	(	PUNCT
fnp-2971	94	18	lfb	lfb	PROPN
fnp-2971	94	19	-	-	PUNCT
fnp-2971	94	20	he	he	PRON
fnp-2971	94	21	;	;	PUNCT
fnp-2971	94	22	scale	scale	NOUN
fnp-2971	94	23	bar	bar	NOUN
fnp-2971	94	24	:	:	PUNCT
fnp-2971	94	25	50	50	NUM
fnp-2971	94	26	µm	µm	NOUN
fnp-2971	94	27	)	)	PUNCT
fnp-2971	94	28	.	.	PUNCT
fnp-2971	95	1	(	(	PUNCT
fnp-2971	95	2	c	c	X
fnp-2971	95	3	)	)	PUNCT
fnp-2971	95	4	app	app	NOUN
fnp-2971	95	5	immunostaining	immunostaine	VERB
fnp-2971	95	6	highlights	highlight	NOUN
fnp-2971	95	7	frequent	frequent	ADJ
fnp-2971	95	8	axonal	axonal	ADJ
fnp-2971	95	9	spheroids	spheroid	NOUN
fnp-2971	95	10	inside	inside	ADP
fnp-2971	95	11	the	the	DET
fnp-2971	95	12	rectangular	rectangular	ADJ
fnp-2971	95	13	inset	inset	NOUN
fnp-2971	95	14	(	(	PUNCT
fnp-2971	95	15	app	app	ADJ
fnp-2971	95	16	;	;	PUNCT
fnp-2971	95	17	scale	scale	NOUN
fnp-2971	95	18	bar	bar	NOUN
fnp-2971	95	19	:	:	PUNCT
fnp-2971	95	20	500	500	NUM
fnp-2971	95	21	µm	µm	NUM
fnp-2971	95	22	)	)	PUNCT
fnp-2971	95	23	.	.	PUNCT
fnp-2971	96	1	(	(	PUNCT
fnp-2971	96	2	d	d	X
fnp-2971	96	3	)	)	PUNCT
fnp-2971	96	4	higher	high	ADJ
fnp-2971	96	5	magnification	magnification	NOUN
fnp-2971	96	6	of	of	ADP
fnp-2971	96	7	(	(	PUNCT
fnp-2971	96	8	c	c	NOUN
fnp-2971	96	9	)	)	PUNCT
fnp-2971	96	10	(	(	PUNCT
fnp-2971	96	11	app	app	X
fnp-2971	96	12	;	;	PUNCT
fnp-2971	96	13	scale	scale	NOUN
fnp-2971	96	14	bar	bar	NOUN
fnp-2971	96	15	:	:	PUNCT
fnp-2971	96	16	100	100	NUM
fnp-2971	96	17	µm	µm	NOUN
fnp-2971	96	18	)	)	PUNCT
fnp-2971	96	19	.	.	PUNCT
fnp-2971	97	1	(	(	PUNCT
fnp-2971	97	2	e	e	X
fnp-2971	97	3	)	)	PUNCT
fnp-2971	97	4	the	the	DET
fnp-2971	97	5	affected	affected	ADJ
fnp-2971	97	6	area	area	NOUN
fnp-2971	97	7	in	in	ADP
fnp-2971	97	8	(	(	PUNCT
fnp-2971	97	9	c	c	NOUN
fnp-2971	97	10	)	)	PUNCT
fnp-2971	97	11	with	with	ADP
fnp-2971	97	12	many	many	ADJ
fnp-2971	97	13	axonal	axonal	ADJ
fnp-2971	97	14	spheroids	spheroid	NOUN
fnp-2971	97	15	in	in	ADP
fnp-2971	97	16	the	the	DET
fnp-2971	97	17	white	white	ADJ
fnp-2971	97	18	matter	matter	NOUN
fnp-2971	97	19	and	and	CCONJ
fnp-2971	97	20	a	a	DET
fnp-2971	97	21	small	small	ADJ
fnp-2971	97	22	area	area	NOUN
fnp-2971	97	23	of	of	ADP
fnp-2971	97	24	adjacent	adjacent	ADJ
fnp-2971	97	25	cortex	cortex	NOUN
fnp-2971	97	26	that	that	PRON
fnp-2971	97	27	shows	show	VERB
fnp-2971	97	28	a	a	DET
fnp-2971	97	29	nearly	nearly	ADV
fnp-2971	97	30	complete	complete	ADJ
fnp-2971	97	31	loss	loss	NOUN
fnp-2971	97	32	of	of	ADP
fnp-2971	97	33	hla	hla	PROPN
fnp-2971	97	34	-	-	PUNCT
fnp-2971	97	35	dr	dr	NOUN
fnp-2971	97	36	-	-	PUNCT
fnp-2971	97	37	expressing	express	VERB
fnp-2971	97	38	ramified	ramified	ADJ
fnp-2971	97	39	microglia	microglia	NOUN
fnp-2971	97	40	(	(	PUNCT
fnp-2971	97	41	inside	inside	ADP
fnp-2971	97	42	the	the	DET
fnp-2971	97	43	polygonal	polygonal	ADJ
fnp-2971	97	44	inset	inset	NOUN
fnp-2971	97	45	)	)	PUNCT
fnp-2971	97	46	and	and	CCONJ
fnp-2971	97	47	only	only	ADV
fnp-2971	97	48	a	a	DET
fnp-2971	97	49	few	few	ADJ
fnp-2971	97	50	scattered	scatter	VERB
fnp-2971	97	51	hla	hla	PROPN
fnp-2971	97	52	-	-	PUNCT
fnp-2971	97	53	dr	dr	NOUN
fnp-2971	97	54	-	-	PUNCT
fnp-2971	97	55	expressing	express	VERB
fnp-2971	97	56	amoeboid	amoeboid	ADJ
fnp-2971	97	57	-	-	PUNCT
fnp-2971	97	58	phenotype	phenotype	NOUN
fnp-2971	97	59	cells	cell	NOUN
fnp-2971	97	60	.	.	PUNCT
fnp-2971	98	1	the	the	DET
fnp-2971	98	2	adjacent	adjacent	ADJ
fnp-2971	98	3	normal	normal	ADJ
fnp-2971	98	4	-	-	PUNCT
fnp-2971	98	5	appearing	appear	VERB
fnp-2971	98	6	areas	area	NOUN
fnp-2971	98	7	show	show	VERB
fnp-2971	98	8	an	an	DET
fnp-2971	98	9	increased	increase	VERB
fnp-2971	98	10	expression	expression	NOUN
fnp-2971	98	11	of	of	ADP
fnp-2971	98	12	hla	hla	PROPN
fnp-2971	98	13	-	-	PUNCT
fnp-2971	98	14	dr	dr	NOUN
fnp-2971	98	15	-	-	ADJ
fnp-2971	98	16	positive	positive	ADJ
fnp-2971	98	17	ramified	ramified	ADJ
fnp-2971	98	18	microglia	microglia	NOUN
fnp-2971	98	19	(	(	PUNCT
fnp-2971	98	20	hla	hla	PROPN
fnp-2971	98	21	-	-	PUNCT
fnp-2971	98	22	dr	dr	PROPN
fnp-2971	98	23	;	;	PUNCT
fnp-2971	98	24	scale	scale	NOUN
fnp-2971	98	25	bar	bar	NOUN
fnp-2971	98	26	:	:	PUNCT
fnp-2971	98	27	1	1	NUM
fnp-2971	98	28	mm	mm	NOUN
fnp-2971	98	29	)	)	PUNCT
fnp-2971	98	30	.	.	PUNCT
fnp-2971	99	1	(	(	PUNCT
fnp-2971	99	2	f	f	X
fnp-2971	99	3	)	)	PUNCT
fnp-2971	99	4	higher	high	ADJ
fnp-2971	99	5	magnification	magnification	NOUN
fnp-2971	99	6	of	of	ADP
fnp-2971	99	7	(	(	PUNCT
fnp-2971	99	8	e	e	NOUN
fnp-2971	99	9	)	)	PUNCT
fnp-2971	99	10	(	(	PUNCT
fnp-2971	99	11	hla	hla	PROPN
fnp-2971	99	12	-	-	PUNCT
fnp-2971	99	13	dr	dr	PROPN
fnp-2971	99	14	;	;	PUNCT
fnp-2971	99	15	scale	scale	NOUN
fnp-2971	99	16	bar	bar	NOUN
fnp-2971	99	17	:	:	PUNCT
fnp-2971	99	18	500	500	NUM
fnp-2971	99	19	µm	µm	NUM
fnp-2971	99	20	)	)	PUNCT
fnp-2971	99	21	.	.	PUNCT
fnp-2971	100	1	(	(	PUNCT
fnp-2971	100	2	g	g	NOUN
fnp-2971	100	3	)	)	PUNCT
fnp-2971	100	4	normal	normal	ADV
fnp-2971	100	5	-	-	PUNCT
fnp-2971	100	6	appearing	appear	VERB
fnp-2971	100	7	white	white	ADJ
fnp-2971	100	8	matter	matter	NOUN
fnp-2971	100	9	adjacent	adjacent	ADJ
fnp-2971	100	10	to	to	ADP
fnp-2971	100	11	the	the	DET
fnp-2971	100	12	affected	affected	ADJ
fnp-2971	100	13	area	area	NOUN
fnp-2971	100	14	shows	show	VERB
fnp-2971	100	15	no	no	DET
fnp-2971	100	16	recognizable	recognizable	ADJ
fnp-2971	100	17	abnormalities	abnormality	NOUN
fnp-2971	100	18	(	(	PUNCT
fnp-2971	100	19	lfb	lfb	PROPN
fnp-2971	100	20	-	-	PUNCT
fnp-2971	100	21	he	he	PRON
fnp-2971	100	22	;	;	PUNCT
fnp-2971	100	23	scale	scale	NOUN
fnp-2971	100	24	bar	bar	NOUN
fnp-2971	100	25	:	:	PUNCT
fnp-2971	100	26	50	50	NUM
fnp-2971	100	27	µm	µm	NOUN
fnp-2971	100	28	)	)	PUNCT
fnp-2971	100	29	.	.	PUNCT
fnp-2971	101	1	(	(	PUNCT
fnp-2971	101	2	h	h	NOUN
fnp-2971	101	3	):	):	PUNCT
fnp-2971	101	4	hla	hla	PROPN
fnp-2971	101	5	-	-	PUNCT
fnp-2971	101	6	dr	dr	PROPN
fnp-2971	101	7	immunostaining	immunostaining	NOUN
fnp-2971	101	8	shows	show	VERB
fnp-2971	101	9	a	a	DET
fnp-2971	101	10	frequent	frequent	ADJ
fnp-2971	101	11	expression	expression	NOUN
fnp-2971	101	12	of	of	ADP
fnp-2971	101	13	hla	hla	PROPN
fnp-2971	101	14	-	-	PUNCT
fnp-2971	101	15	dr	dr	PROPN
fnp-2971	101	16	-	-	PUNCT
fnp-2971	101	17	immunopositive	immunopositive	ADJ
fnp-2971	101	18	ramified	ramified	ADJ
fnp-2971	101	19	microglia	microglia	NOUN
fnp-2971	101	20	(	(	PUNCT
fnp-2971	101	21	hla	hla	PROPN
fnp-2971	101	22	-	-	PUNCT
fnp-2971	101	23	dr	dr	PROPN
fnp-2971	101	24	;	;	PUNCT
fnp-2971	101	25	scale	scale	NOUN
fnp-2971	101	26	bar	bar	NOUN
fnp-2971	101	27	:	:	PUNCT
fnp-2971	101	28	50	50	NUM
fnp-2971	101	29	µm	µm	NOUN
fnp-2971	101	30	)	)	PUNCT
fnp-2971	101	31	.	.	PUNCT
fnp-2971	102	1	all	all	DET
fnp-2971	102	2	images	image	NOUN
fnp-2971	102	3	in	in	ADP
fnp-2971	102	4	this	this	DET
fnp-2971	102	5	figure	figure	NOUN
fnp-2971	102	6	are	be	AUX
fnp-2971	102	7	representative	representative	ADJ
fnp-2971	102	8	of	of	ADP
fnp-2971	102	9	case	case	NOUN
fnp-2971	102	10	2	2	NUM
fnp-2971	102	11	.	.	PUNCT
fnp-2971	102	12	figure	figure	NOUN
fnp-2971	102	13	2	2	NUM
fnp-2971	102	14	.	.	PUNCT
fnp-2971	102	15	cortical	cortical	ADJ
fnp-2971	102	16	involvement	involvement	NOUN
fnp-2971	102	17	in	in	ADP
fnp-2971	102	18	alas	alas	INTJ
fnp-2971	102	19	.	.	PUNCT
fnp-2971	103	1	(	(	PUNCT
fnp-2971	103	2	a	a	X
fnp-2971	103	3	)	)	PUNCT
fnp-2971	103	4	focal	focal	ADJ
fnp-2971	103	5	involvement	involvement	NOUN
fnp-2971	103	6	of	of	ADP
fnp-2971	103	7	the	the	DET
fnp-2971	103	8	upper	upper	ADJ
fnp-2971	103	9	cortex	cortex	NOUN
fnp-2971	103	10	with	with	ADP
fnp-2971	103	11	frequent	frequent	ADJ
fnp-2971	103	12	axonal	axonal	ADJ
fnp-2971	103	13	spheroids	spheroid	NOUN
fnp-2971	103	14	(	(	PUNCT
fnp-2971	103	15	inside	inside	ADP
fnp-2971	103	16	ellipse	ellipse	NOUN
fnp-2971	103	17	)	)	PUNCT
fnp-2971	103	18	compared	compare	VERB
fnp-2971	103	19	to	to	ADP
fnp-2971	103	20	the	the	DET
fnp-2971	103	21	cortex	cortex	NOUN
fnp-2971	103	22	on	on	ADP
fnp-2971	103	23	the	the	DET
fnp-2971	103	24	right	right	ADJ
fnp-2971	103	25	side	side	NOUN
fnp-2971	103	26	.	.	PUNCT
fnp-2971	104	1	the	the	DET
fnp-2971	104	2	underlying	underlie	VERB
fnp-2971	104	3	u	u	NOUN
fnp-2971	104	4	-	-	NOUN
fnp-2971	104	5	fibers	fiber	NOUN
fnp-2971	104	6	are	be	AUX
fnp-2971	104	7	also	also	ADV
fnp-2971	104	8	affected	affect	VERB
fnp-2971	104	9	(	(	PUNCT
fnp-2971	104	10	lfb	lfb	PROPN
fnp-2971	104	11	-	-	PUNCT
fnp-2971	104	12	he	he	PRON
fnp-2971	104	13	;	;	PUNCT
fnp-2971	104	14	scale	scale	NOUN
fnp-2971	104	15	bar	bar	NOUN
fnp-2971	104	16	:	:	PUNCT
fnp-2971	104	17	500	500	NUM
fnp-2971	104	18	µm	µm	NUM
fnp-2971	104	19	)	)	PUNCT
fnp-2971	104	20	.	.	PUNCT
fnp-2971	105	1	(	(	PUNCT
fnp-2971	105	2	b	b	X
fnp-2971	105	3	)	)	PUNCT
fnp-2971	105	4	higher	high	ADJ
fnp-2971	105	5	magnification	magnification	NOUN
fnp-2971	105	6	of	of	ADP
fnp-2971	105	7	(	(	PUNCT
fnp-2971	105	8	a	a	NOUN
fnp-2971	105	9	)	)	PUNCT
fnp-2971	105	10	from	from	ADP
fnp-2971	105	11	the	the	DET
fnp-2971	105	12	cortical	cortical	ADJ
fnp-2971	105	13	area	area	NOUN
fnp-2971	105	14	inside	inside	ADP
fnp-2971	105	15	the	the	DET
fnp-2971	105	16	ellipse	ellipse	NOUN
fnp-2971	105	17	(	(	PUNCT
fnp-2971	105	18	lfb	lfb	PROPN
fnp-2971	105	19	-	-	PUNCT
fnp-2971	105	20	he	he	PRON
fnp-2971	105	21	;	;	PUNCT
fnp-2971	105	22	scale	scale	NOUN
fnp-2971	105	23	bar	bar	NOUN
fnp-2971	105	24	:	:	PUNCT
fnp-2971	105	25	50	50	NUM
fnp-2971	105	26	µm	µm	NOUN
fnp-2971	105	27	)	)	PUNCT
fnp-2971	105	28	.	.	PUNCT
fnp-2971	106	1	(	(	PUNCT
fnp-2971	106	2	a	a	X
fnp-2971	106	3	)	)	PUNCT
fnp-2971	106	4	and	and	CCONJ
fnp-2971	106	5	(	(	PUNCT
fnp-2971	106	6	b	b	X
fnp-2971	106	7	)	)	PUNCT
fnp-2971	106	8	represent	represent	VERB
fnp-2971	106	9	an	an	DET
fnp-2971	106	10	inset	inset	NOUN
fnp-2971	106	11	(	(	PUNCT
fnp-2971	106	12	higher	high	ADJ
fnp-2971	106	13	magnification	magnification	NOUN
fnp-2971	106	14	of	of	ADP
fnp-2971	106	15	the	the	DET
fnp-2971	106	16	upper	upper	ADJ
fnp-2971	106	17	rectangle	rectangle	NOUN
fnp-2971	106	18	)	)	PUNCT
fnp-2971	106	19	in	in	ADP
fnp-2971	106	20	figure	figure	NOUN
fnp-2971	106	21	4a	4a	NOUN
fnp-2971	106	22	.	.	PUNCT
fnp-2971	107	1	(	(	PUNCT
fnp-2971	107	2	c	c	X
fnp-2971	107	3	)	)	PUNCT
fnp-2971	107	4	hla	hla	PROPN
fnp-2971	107	5	-	-	PUNCT
fnp-2971	107	6	dr	dr	PROPN
fnp-2971	107	7	immunostaining	immunostaining	NOUN
fnp-2971	107	8	shows	show	VERB
fnp-2971	107	9	a	a	DET
fnp-2971	107	10	complete	complete	ADJ
fnp-2971	107	11	focal	focal	ADJ
fnp-2971	107	12	loss	loss	NOUN
fnp-2971	107	13	of	of	ADP
fnp-2971	107	14	staining	stain	VERB
fnp-2971	107	15	in	in	ADP
fnp-2971	107	16	the	the	DET
fnp-2971	107	17	area	area	NOUN
fnp-2971	107	18	with	with	ADP
fnp-2971	107	19	frequent	frequent	ADJ
fnp-2971	107	20	axonal	axonal	ADJ
fnp-2971	107	21	spheroids	spheroid	NOUN
fnp-2971	107	22	(	(	PUNCT
fnp-2971	107	23	inside	inside	ADP
fnp-2971	107	24	ellipse	ellipse	NOUN
fnp-2971	107	25	)	)	PUNCT
fnp-2971	107	26	(	(	PUNCT
fnp-2971	107	27	hla	hla	PROPN
fnp-2971	107	28	-	-	PUNCT
fnp-2971	107	29	dr	dr	PROPN
fnp-2971	107	30	;	;	PUNCT
fnp-2971	107	31	scale	scale	NOUN
fnp-2971	107	32	bar	bar	NOUN
fnp-2971	107	33	:	:	PUNCT
fnp-2971	107	34	500	500	NUM
fnp-2971	107	35	µm	µm	NUM
fnp-2971	107	36	)	)	PUNCT
fnp-2971	107	37	.	.	PUNCT
fnp-2971	108	1	(	(	PUNCT
fnp-2971	108	2	d	d	X
fnp-2971	108	3	)	)	PUNCT
fnp-2971	108	4	higher	high	ADJ
fnp-2971	108	5	magnification	magnification	NOUN
fnp-2971	108	6	of	of	ADP
fnp-2971	108	7	(	(	PUNCT
fnp-2971	108	8	c	c	NOUN
fnp-2971	108	9	)	)	PUNCT
fnp-2971	108	10	to	to	PART
fnp-2971	108	11	highlight	highlight	VERB
fnp-2971	108	12	the	the	DET
fnp-2971	108	13	presence	presence	NOUN
fnp-2971	108	14	of	of	ADP
fnp-2971	108	15	axonal	axonal	ADJ
fnp-2971	108	16	spheroids	spheroid	NOUN
fnp-2971	108	17	(	(	PUNCT
fnp-2971	108	18	arrows	arrow	NOUN
fnp-2971	108	19	)	)	PUNCT
fnp-2971	108	20	associated	associate	VERB
fnp-2971	108	21	with	with	ADP
fnp-2971	108	22	a	a	DET
fnp-2971	108	23	complete	complete	ADJ
fnp-2971	108	24	absence	absence	NOUN
fnp-2971	108	25	of	of	ADP
fnp-2971	108	26	hla	hla	PROPN
fnp-2971	108	27	-	-	PUNCT
fnp-2971	108	28	dr	dr	NOUN
fnp-2971	108	29	-	-	PUNCT
fnp-2971	108	30	expressing	express	VERB
fnp-2971	108	31	ramified	ramified	ADJ
fnp-2971	108	32	microglia	microglia	NOUN
fnp-2971	108	33	(	(	PUNCT
fnp-2971	108	34	hla	hla	PROPN
fnp-2971	108	35	-	-	PUNCT
fnp-2971	108	36	dr	dr	PROPN
fnp-2971	108	37	;	;	PUNCT
fnp-2971	108	38	scale	scale	NOUN
fnp-2971	108	39	bar	bar	NOUN
fnp-2971	108	40	:	:	PUNCT
fnp-2971	108	41	50	50	NUM
fnp-2971	108	42	µm	µm	NOUN
fnp-2971	108	43	)	)	PUNCT
fnp-2971	108	44	.	.	PUNCT
fnp-2971	109	1	(	(	PUNCT
fnp-2971	109	2	e	e	NOUN
fnp-2971	109	3	):	):	PUNCT
fnp-2971	109	4	a	a	DET
fnp-2971	109	5	small	small	ADJ
fnp-2971	109	6	cortical	cortical	ADJ
fnp-2971	109	7	area	area	NOUN
fnp-2971	109	8	(	(	PUNCT
fnp-2971	109	9	inside	inside	ADP
fnp-2971	109	10	the	the	DET
fnp-2971	109	11	rectangle	rectangle	NOUN
fnp-2971	109	12	)	)	PUNCT
fnp-2971	109	13	with	with	ADP
fnp-2971	109	14	frequent	frequent	ADJ
fnp-2971	109	15	axonal	axonal	ADJ
fnp-2971	109	16	spheroids	spheroid	NOUN
fnp-2971	109	17	(	(	PUNCT
fnp-2971	109	18	app	app	ADJ
fnp-2971	109	19	;	;	PUNCT
fnp-2971	109	20	scale	scale	NOUN
fnp-2971	109	21	bar	bar	NOUN
fnp-2971	109	22	:	:	PUNCT
fnp-2971	109	23	500	500	NUM
fnp-2971	109	24	µm	µm	NUM
fnp-2971	109	25	)	)	PUNCT
fnp-2971	109	26	.	.	PUNCT
fnp-2971	110	1	(	(	PUNCT
fnp-2971	110	2	f	f	X
fnp-2971	110	3	)	)	PUNCT
fnp-2971	110	4	higher	high	ADJ
fnp-2971	110	5	magnification	magnification	NOUN
fnp-2971	110	6	of	of	ADP
fnp-2971	110	7	(	(	PUNCT
fnp-2971	110	8	e	e	NOUN
fnp-2971	110	9	)	)	PUNCT
fnp-2971	110	10	(	(	PUNCT
fnp-2971	110	11	app	app	X
fnp-2971	110	12	;	;	PUNCT
fnp-2971	110	13	scale	scale	NOUN
fnp-2971	110	14	bar	bar	NOUN
fnp-2971	110	15	:	:	PUNCT
fnp-2971	110	16	50	50	NUM
fnp-2971	110	17	µm	µm	NOUN
fnp-2971	110	18	.	.	PUNCT
fnp-2971	110	19	)	)	PUNCT
fnp-2971	110	20	.	.	PUNCT
fnp-2971	111	1	(	(	PUNCT
fnp-2971	111	2	g	g	NOUN
fnp-2971	111	3	)	)	PUNCT
fnp-2971	111	4	hla	hla	PROPN
fnp-2971	111	5	-	-	PUNCT
fnp-2971	111	6	dr	dr	PROPN
fnp-2971	111	7	loss	loss	NOUN
fnp-2971	111	8	is	be	AUX
fnp-2971	111	9	limited	limit	VERB
fnp-2971	111	10	to	to	ADP
fnp-2971	111	11	the	the	DET
fnp-2971	111	12	very	very	ADV
fnp-2971	111	13	small	small	ADJ
fnp-2971	111	14	affected	affected	ADJ
fnp-2971	111	15	area	area	NOUN
fnp-2971	111	16	(	(	PUNCT
fnp-2971	111	17	inside	inside	ADP
fnp-2971	111	18	the	the	DET
fnp-2971	111	19	rectangle	rectangle	NOUN
fnp-2971	111	20	)	)	PUNCT
fnp-2971	111	21	,	,	PUNCT
fnp-2971	111	22	while	while	SCONJ
fnp-2971	111	23	the	the	DET
fnp-2971	111	24	surrounding	surround	VERB
fnp-2971	111	25	cortical	cortical	ADJ
fnp-2971	111	26	areas	area	NOUN
fnp-2971	111	27	show	show	VERB
fnp-2971	111	28	hla	hla	PROPN
fnp-2971	111	29	-	-	PUNCT
fnp-2971	111	30	dr	dr	NOUN
fnp-2971	111	31	-	-	PUNCT
fnp-2971	111	32	expressing	express	VERB
fnp-2971	111	33	ramified	ramified	ADJ
fnp-2971	111	34	microglia	microglia	NOUN
fnp-2971	111	35	(	(	PUNCT
fnp-2971	111	36	hla	hla	PROPN
fnp-2971	111	37	-	-	PUNCT
fnp-2971	111	38	dr	dr	PROPN
fnp-2971	111	39	;	;	PUNCT
fnp-2971	111	40	scale	scale	NOUN
fnp-2971	111	41	bar	bar	NOUN
fnp-2971	111	42	:	:	PUNCT
fnp-2971	111	43	500	500	NUM
fnp-2971	111	44	µm	µm	NUM
fnp-2971	111	45	)	)	PUNCT
fnp-2971	111	46	.	.	PUNCT
fnp-2971	112	1	(	(	PUNCT
fnp-2971	112	2	h	h	NOUN
fnp-2971	112	3	)	)	PUNCT
fnp-2971	112	4	higher	high	ADJ
fnp-2971	112	5	magnification	magnification	NOUN
fnp-2971	112	6	of	of	ADP
fnp-2971	112	7	(	(	PUNCT
fnp-2971	112	8	g	g	NOUN
fnp-2971	112	9	)	)	PUNCT
fnp-2971	112	10	(	(	PUNCT
fnp-2971	112	11	hla	hla	PROPN
fnp-2971	112	12	-	-	PUNCT
fnp-2971	112	13	dr	dr	PROPN
fnp-2971	112	14	;	;	PUNCT
fnp-2971	112	15	scale	scale	NOUN
fnp-2971	112	16	bar	bar	NOUN
fnp-2971	112	17	:	:	PUNCT
fnp-2971	112	18	200	200	NUM
fnp-2971	112	19	µm	µm	NOUN
fnp-2971	112	20	)	)	PUNCT
fnp-2971	112	21	.	.	PUNCT
fnp-2971	113	1	all	all	DET
fnp-2971	113	2	images	image	NOUN
fnp-2971	113	3	in	in	ADP
fnp-2971	113	4	this	this	DET
fnp-2971	113	5	figure	figure	NOUN
fnp-2971	113	6	are	be	AUX
fnp-2971	113	7	representative	representative	ADJ
fnp-2971	113	8	of	of	ADP
fnp-2971	113	9	case	case	NOUN
fnp-2971	113	10	6	6	NUM
fnp-2971	113	11	.	.	PUNCT
fnp-2971	113	12	figure	figure	NOUN
fnp-2971	113	13	3	3	NUM
fnp-2971	113	14	.	.	PUNCT
fnp-2971	113	15	microglia	microglia	ADJ
fnp-2971	113	16	and	and	CCONJ
fnp-2971	113	17	axonal	axonal	ADJ
fnp-2971	113	18	spheroids	spheroid	NOUN
fnp-2971	113	19	in	in	ADP
fnp-2971	113	20	stage	stage	NOUN
fnp-2971	113	21	2	2	NUM
fnp-2971	113	22	pathology	pathology	NOUN
fnp-2971	113	23	.	.	PUNCT
fnp-2971	114	1	(	(	PUNCT
fnp-2971	114	2	a	a	X
fnp-2971	114	3	)	)	PUNCT
fnp-2971	114	4	decreased	decrease	VERB
fnp-2971	114	5	myelin	myelin	NOUN
fnp-2971	114	6	staining	staining	NOUN
fnp-2971	114	7	in	in	ADP
fnp-2971	114	8	the	the	DET
fnp-2971	114	9	deep	deep	ADJ
fnp-2971	114	10	subcortical	subcortical	ADJ
fnp-2971	114	11	white	white	ADJ
fnp-2971	114	12	matter	matter	NOUN
fnp-2971	114	13	(	(	PUNCT
fnp-2971	114	14	mostly	mostly	ADV
fnp-2971	114	15	inside	inside	ADP
fnp-2971	114	16	the	the	DET
fnp-2971	114	17	inset	inset	NOUN
fnp-2971	114	18	)	)	PUNCT
fnp-2971	114	19	compared	compare	VERB
fnp-2971	114	20	to	to	ADP
fnp-2971	114	21	the	the	DET
fnp-2971	114	22	surrounding	surround	VERB
fnp-2971	114	23	subcortical	subcortical	ADJ
fnp-2971	114	24	u	u	NOUN
fnp-2971	114	25	-	-	NOUN
fnp-2971	114	26	fibers	fiber	NOUN
fnp-2971	114	27	(	(	PUNCT
fnp-2971	114	28	lfb	lfb	PROPN
fnp-2971	114	29	-	-	PUNCT
fnp-2971	114	30	he	he	PRON
fnp-2971	114	31	,	,	PUNCT
fnp-2971	114	32	scale	scale	NOUN
fnp-2971	114	33	bar	bar	NOUN
fnp-2971	114	34	:	:	PUNCT
fnp-2971	114	35	500	500	NUM
fnp-2971	114	36	µm	µm	NUM
fnp-2971	114	37	)	)	PUNCT
fnp-2971	114	38	.	.	PUNCT
fnp-2971	115	1	(	(	PUNCT
fnp-2971	115	2	b	b	X
fnp-2971	115	3	)	)	PUNCT
fnp-2971	115	4	higher	high	ADJ
fnp-2971	115	5	magnification	magnification	NOUN
fnp-2971	115	6	of	of	ADP
fnp-2971	115	7	(	(	PUNCT
fnp-2971	115	8	a	a	NOUN
fnp-2971	115	9	)	)	PUNCT
fnp-2971	115	10	(	(	PUNCT
fnp-2971	115	11	lfb	lfb	PROPN
fnp-2971	115	12	-	-	PUNCT
fnp-2971	115	13	he	he	PRON
fnp-2971	115	14	;	;	PUNCT
fnp-2971	115	15	,	,	PUNCT
fnp-2971	115	16	scale	scale	NOUN
fnp-2971	115	17	bar	bar	NOUN
fnp-2971	115	18	:	:	PUNCT
fnp-2971	115	19	200	200	NUM
fnp-2971	115	20	µm	µm	NUM
fnp-2971	115	21	)	)	PUNCT
fnp-2971	115	22	.	.	PUNCT
fnp-2971	116	1	(	(	PUNCT
fnp-2971	116	2	c	c	X
fnp-2971	116	3	)	)	PUNCT
fnp-2971	116	4	the	the	DET
fnp-2971	116	5	area	area	NOUN
fnp-2971	116	6	showing	show	VERB
fnp-2971	116	7	decreased	decrease	VERB
fnp-2971	116	8	myelin	myelin	NOUN
fnp-2971	116	9	staining	staining	NOUN
fnp-2971	116	10	in	in	ADP
fnp-2971	116	11	(	(	PUNCT
fnp-2971	116	12	a	a	X
fnp-2971	116	13	)	)	PUNCT
fnp-2971	116	14	shows	show	VERB
fnp-2971	116	15	a	a	DET
fnp-2971	116	16	complete	complete	ADJ
fnp-2971	116	17	loss	loss	NOUN
fnp-2971	116	18	of	of	ADP
fnp-2971	116	19	hla	hla	PROPN
fnp-2971	116	20	-	-	PUNCT
fnp-2971	116	21	dr	dr	NOUN
fnp-2971	116	22	-	-	PUNCT
fnp-2971	116	23	expressing	express	VERB
fnp-2971	116	24	ramified	ramified	ADJ
fnp-2971	116	25	microglia	microglia	NOUN
fnp-2971	116	26	(	(	PUNCT
fnp-2971	116	27	mostly	mostly	ADV
fnp-2971	116	28	inside	inside	ADP
fnp-2971	116	29	the	the	DET
fnp-2971	116	30	inset	inset	NOUN
fnp-2971	116	31	)	)	PUNCT
fnp-2971	116	32	but	but	CCONJ
fnp-2971	116	33	moderate	moderate	ADJ
fnp-2971	116	34	numbers	number	NOUN
fnp-2971	116	35	of	of	ADP
fnp-2971	116	36	hla	hla	PROPN
fnp-2971	116	37	-	-	PUNCT
fnp-2971	116	38	dr	dr	PROPN
fnp-2971	116	39	-	-	PUNCT
fnp-2971	116	40	immunopositive	immunopositive	ADJ
fnp-2971	116	41	cells	cell	NOUN
fnp-2971	116	42	with	with	ADP
fnp-2971	116	43	amoeboid	amoeboid	ADJ
fnp-2971	116	44	phenotype	phenotype	NOUN
fnp-2971	116	45	.	.	PUNCT
fnp-2971	117	1	the	the	DET
fnp-2971	117	2	adjacent	adjacent	ADJ
fnp-2971	117	3	white	white	ADJ
fnp-2971	117	4	matter	matter	NOUN
fnp-2971	117	5	shows	show	VERB
fnp-2971	117	6	frequent	frequent	ADJ
fnp-2971	117	7	hla	hla	PROPN
fnp-2971	117	8	-	-	PUNCT
fnp-2971	117	9	dr	dr	NOUN
fnp-2971	117	10	-	-	PUNCT
fnp-2971	117	11	expressing	express	VERB
fnp-2971	117	12	ramified	ramified	ADJ
fnp-2971	117	13	microglia	microglia	NOUN
fnp-2971	117	14	(	(	PUNCT
fnp-2971	117	15	hla	hla	PROPN
fnp-2971	117	16	-	-	PUNCT
fnp-2971	117	17	dr	dr	PROPN
fnp-2971	117	18	;	;	PUNCT
fnp-2971	117	19	scale	scale	NOUN
fnp-2971	117	20	bar	bar	NOUN
fnp-2971	117	21	:	:	PUNCT
fnp-2971	117	22	500	500	NUM
fnp-2971	117	23	µm	µm	NUM
fnp-2971	117	24	)	)	PUNCT
fnp-2971	117	25	.	.	PUNCT
fnp-2971	118	1	(	(	PUNCT
fnp-2971	118	2	d	d	X
fnp-2971	118	3	)	)	PUNCT
fnp-2971	118	4	higher	high	ADJ
fnp-2971	118	5	magnification	magnification	NOUN
fnp-2971	118	6	of	of	ADP
fnp-2971	118	7	(	(	PUNCT
fnp-2971	118	8	c	c	NOUN
fnp-2971	118	9	)	)	PUNCT
fnp-2971	118	10	(	(	PUNCT
fnp-2971	118	11	scale	scale	NOUN
fnp-2971	118	12	bar	bar	NOUN
fnp-2971	118	13	:	:	PUNCT
fnp-2971	118	14	200	200	NUM
fnp-2971	118	15	µm	µm	NOUN
fnp-2971	118	16	)	)	PUNCT
fnp-2971	118	17	.	.	PUNCT
fnp-2971	119	1	(	(	PUNCT
fnp-2971	119	2	e	e	X
fnp-2971	119	3	)	)	PUNCT
fnp-2971	119	4	app	app	ADJ
fnp-2971	119	5	-	-	PUNCT
fnp-2971	119	6	immunopositive	immunopositive	ADJ
fnp-2971	119	7	axonal	axonal	ADJ
fnp-2971	119	8	spheroids	spheroid	NOUN
fnp-2971	119	9	are	be	AUX
fnp-2971	119	10	limited	limit	VERB
fnp-2971	119	11	to	to	ADP
fnp-2971	119	12	the	the	DET
fnp-2971	119	13	area	area	NOUN
fnp-2971	119	14	(	(	PUNCT
fnp-2971	119	15	mostly	mostly	ADV
fnp-2971	119	16	inside	inside	ADP
fnp-2971	119	17	the	the	DET
fnp-2971	119	18	inset	inset	NOUN
fnp-2971	119	19	)	)	PUNCT
fnp-2971	119	20	showing	show	VERB
fnp-2971	119	21	an	an	DET
fnp-2971	119	22	extensive	extensive	ADJ
fnp-2971	119	23	loss	loss	NOUN
fnp-2971	119	24	of	of	ADP
fnp-2971	119	25	ramified	ramified	ADJ
fnp-2971	119	26	microglia	microglia	NOUN
fnp-2971	119	27	and	and	CCONJ
fnp-2971	119	28	presence	presence	NOUN
fnp-2971	119	29	of	of	ADP
fnp-2971	119	30	hla	hla	PROPN
fnp-2971	119	31	-	-	PUNCT
fnp-2971	119	32	dr	dr	PROPN
fnp-2971	119	33	expressing	express	VERB
fnp-2971	119	34	cells	cell	NOUN
fnp-2971	119	35	with	with	ADP
fnp-2971	119	36	amoeboid	amoeboid	ADJ
fnp-2971	119	37	phenotype	phenotype	NOUN
fnp-2971	119	38	(	(	PUNCT
fnp-2971	119	39	app	app	ADJ
fnp-2971	119	40	;	;	PUNCT
fnp-2971	119	41	scale	scale	NOUN
fnp-2971	119	42	bar	bar	NOUN
fnp-2971	119	43	:	:	PUNCT
fnp-2971	119	44	500	500	NUM
fnp-2971	119	45	µm	µm	NUM
fnp-2971	119	46	)	)	PUNCT
fnp-2971	119	47	.	.	PUNCT
fnp-2971	120	1	(	(	PUNCT
fnp-2971	120	2	f	f	X
fnp-2971	120	3	)	)	PUNCT
fnp-2971	120	4	higher	high	ADJ
fnp-2971	120	5	magnification	magnification	NOUN
fnp-2971	120	6	of	of	ADP
fnp-2971	120	7	(	(	PUNCT
fnp-2971	120	8	e	e	NOUN
fnp-2971	120	9	)	)	PUNCT
fnp-2971	120	10	(	(	PUNCT
fnp-2971	120	11	app	app	X
fnp-2971	120	12	;	;	PUNCT
fnp-2971	120	13	scale	scale	NOUN
fnp-2971	120	14	bar	bar	NOUN
fnp-2971	120	15	:	:	PUNCT
fnp-2971	120	16	200	200	NUM
fnp-2971	120	17	µm	µm	NUM
fnp-2971	120	18	)	)	PUNCT
fnp-2971	120	19	.	.	PUNCT
fnp-2971	121	1	(	(	PUNCT
fnp-2971	121	2	g	g	NOUN
fnp-2971	121	3	):	):	PUNCT
fnp-2971	121	4	another	another	DET
fnp-2971	121	5	area	area	NOUN
fnp-2971	121	6	with	with	ADP
fnp-2971	121	7	decreased	decrease	VERB
fnp-2971	121	8	myelin	myelin	NOUN
fnp-2971	121	9	staining	staining	NOUN
fnp-2971	121	10	due	due	ADP
fnp-2971	121	11	to	to	ADP
fnp-2971	121	12	a	a	DET
fnp-2971	121	13	prominent	prominent	ADJ
fnp-2971	121	14	loss	loss	NOUN
fnp-2971	121	15	of	of	ADP
fnp-2971	121	16	myelinated	myelinated	ADJ
fnp-2971	121	17	fibers	fiber	NOUN
fnp-2971	121	18	but	but	CCONJ
fnp-2971	121	19	without	without	ADP
fnp-2971	121	20	axonal	axonal	ADJ
fnp-2971	121	21	spheroids	spheroid	NOUN
fnp-2971	121	22	(	(	PUNCT
fnp-2971	121	23	lfb	lfb	PROPN
fnp-2971	121	24	-	-	PUNCT
fnp-2971	121	25	he	he	PRON
fnp-2971	121	26	;	;	PUNCT
fnp-2971	121	27	scale	scale	NOUN
fnp-2971	121	28	bar	bar	NOUN
fnp-2971	121	29	:	:	PUNCT
fnp-2971	121	30	50	50	NUM
fnp-2971	121	31	µm	µm	NOUN
fnp-2971	121	32	)	)	PUNCT
fnp-2971	121	33	.	.	PUNCT
fnp-2971	122	1	(	(	PUNCT
fnp-2971	122	2	h	h	NOUN
fnp-2971	122	3	)	)	PUNCT
fnp-2971	122	4	scattered	scatter	VERB
fnp-2971	122	5	hla	hla	PROPN
fnp-2971	122	6	-	-	PUNCT
fnp-2971	122	7	dr	dr	PROPN
fnp-2971	122	8	-	-	PUNCT
fnp-2971	122	9	immunopositive	immunopositive	ADJ
fnp-2971	122	10	cells	cell	NOUN
fnp-2971	122	11	with	with	ADP
fnp-2971	122	12	amoeboid	amoeboid	ADJ
fnp-2971	122	13	phenotype	phenotype	NOUN
fnp-2971	122	14	in	in	ADP
fnp-2971	122	15	the	the	DET
fnp-2971	122	16	same	same	ADJ
fnp-2971	122	17	area	area	NOUN
fnp-2971	122	18	(	(	PUNCT
fnp-2971	122	19	hla	hla	PROPN
fnp-2971	122	20	-	-	PUNCT
fnp-2971	122	21	dr	dr	PROPN
fnp-2971	122	22	;	;	PUNCT
fnp-2971	122	23	scale	scale	NOUN
fnp-2971	122	24	bar	bar	NOUN
fnp-2971	122	25	:	:	PUNCT
fnp-2971	122	26	100	100	NUM
fnp-2971	122	27	µm	µm	NOUN
fnp-2971	122	28	)	)	PUNCT
fnp-2971	122	29	.	.	PUNCT
fnp-2971	123	1	all	all	DET
fnp-2971	123	2	images	image	NOUN
fnp-2971	123	3	in	in	ADP
fnp-2971	123	4	this	this	DET
fnp-2971	123	5	figure	figure	NOUN
fnp-2971	123	6	are	be	AUX
fnp-2971	123	7	representative	representative	ADJ
fnp-2971	123	8	of	of	ADP
fnp-2971	123	9	case	case	NOUN
fnp-2971	123	10	5	5	NUM
fnp-2971	123	11	.	.	PUNCT
fnp-2971	124	1	in	in	ADP
fnp-2971	124	2	stage	stage	NOUN
fnp-2971	124	3	3	3	NUM
fnp-2971	124	4	pathology	pathology	NOUN
fnp-2971	124	5	,	,	PUNCT
fnp-2971	124	6	the	the	DET
fnp-2971	124	7	white	white	ADJ
fnp-2971	124	8	matter	matter	NOUN
fnp-2971	124	9	showed	show	VERB
fnp-2971	124	10	a	a	DET
fnp-2971	124	11	marked	mark	VERB
fnp-2971	124	12	loss	loss	NOUN
fnp-2971	124	13	of	of	ADP
fnp-2971	124	14	myelinated	myelinated	ADJ
fnp-2971	124	15	axons	axon	NOUN
fnp-2971	124	16	and	and	CCONJ
fnp-2971	124	17	a	a	DET
fnp-2971	124	18	relative	relative	ADJ
fnp-2971	124	19	preservation	preservation	NOUN
fnp-2971	124	20	of	of	ADP
fnp-2971	124	21	the	the	DET
fnp-2971	124	22	subcortical	subcortical	ADJ
fnp-2971	124	23	u	u	NOUN
fnp-2971	124	24	-	-	NOUN
fnp-2971	124	25	fibers	fiber	NOUN
fnp-2971	124	26	(	(	PUNCT
fnp-2971	124	27	figure	figure	NOUN
fnp-2971	124	28	4a	4a	NUM
fnp-2971	124	29	)	)	PUNCT
fnp-2971	124	30	,	,	PUNCT
fnp-2971	124	31	which	which	PRON
fnp-2971	124	32	was	be	AUX
fnp-2971	124	33	classified	classify	VERB
fnp-2971	124	34	as	as	ADP
fnp-2971	124	35	a	a	DET
fnp-2971	124	36	“	"	PUNCT
fnp-2971	124	37	leukodystrophy	leukodystrophy	NOUN
fnp-2971	124	38	-	-	PUNCT
fnp-2971	124	39	like	like	ADJ
fnp-2971	124	40	”	"	PUNCT
fnp-2971	124	41	pattern	pattern	NOUN
fnp-2971	124	42	.	.	PUNCT
fnp-2971	125	1	although	although	SCONJ
fnp-2971	125	2	the	the	DET
fnp-2971	125	3	white	white	ADJ
fnp-2971	125	4	matter	matter	NOUN
fnp-2971	125	5	in	in	ADP
fnp-2971	125	6	this	this	DET
fnp-2971	125	7	area	area	NOUN
fnp-2971	125	8	as	as	ADP
fnp-2971	125	9	a	a	DET
fnp-2971	125	10	whole	whole	NOUN
fnp-2971	125	11	was	be	AUX
fnp-2971	125	12	considered	consider	VERB
fnp-2971	125	13	stage	stage	NOUN
fnp-2971	125	14	3	3	NUM
fnp-2971	125	15	pathology	pathology	NOUN
fnp-2971	125	16	,	,	PUNCT
fnp-2971	125	17	hla	hla	PROPN
fnp-2971	125	18	-	-	PUNCT
fnp-2971	125	19	dr	dr	PROPN
fnp-2971	125	20	immunostaining	immunostaining	NOUN
fnp-2971	125	21	highlighted	highlight	VERB
fnp-2971	125	22	different	different	ADJ
fnp-2971	125	23	patterns	pattern	NOUN
fnp-2971	125	24	of	of	ADP
fnp-2971	125	25	staining	stain	VERB
fnp-2971	125	26	(	(	PUNCT
fnp-2971	125	27	figure	figure	NOUN
fnp-2971	125	28	4b	4b	PROPN
fnp-2971	125	29	)	)	PUNCT
fnp-2971	125	30	,	,	PUNCT
fnp-2971	125	31	which	which	PRON
fnp-2971	125	32	allowed	allow	VERB
fnp-2971	125	33	us	we	PRON
fnp-2971	125	34	to	to	PART
fnp-2971	125	35	appreciate	appreciate	VERB
fnp-2971	125	36	variations	variation	NOUN
fnp-2971	125	37	in	in	ADP
fnp-2971	125	38	the	the	DET
fnp-2971	125	39	preservation	preservation	NOUN
fnp-2971	125	40	of	of	ADP
fnp-2971	125	41	the	the	DET
fnp-2971	125	42	white	white	ADJ
fnp-2971	125	43	matter	matter	NOUN
fnp-2971	125	44	and	and	CCONJ
fnp-2971	125	45	the	the	DET
fnp-2971	125	46	distribution	distribution	NOUN
fnp-2971	125	47	of	of	ADP
fnp-2971	125	48	hla	hla	PROPN
fnp-2971	125	49	-	-	PUNCT
fnp-2971	125	50	dr	dr	NOUN
fnp-2971	125	51	-	-	PUNCT
fnp-2971	125	52	expressing	express	VERB
fnp-2971	125	53	cells	cell	NOUN
fnp-2971	125	54	in	in	ADP
fnp-2971	125	55	stage	stage	NOUN
fnp-2971	125	56	3	3	NUM
fnp-2971	125	57	.	.	PUNCT
fnp-2971	126	1	we	we	PRON
fnp-2971	126	2	could	could	AUX
fnp-2971	126	3	observe	observe	VERB
fnp-2971	126	4	areas	area	NOUN
fnp-2971	126	5	of	of	ADP
fnp-2971	126	6	compact	compact	ADJ
fnp-2971	126	7	neuropil	neuropil	NOUN
fnp-2971	126	8	in	in	ADP
fnp-2971	126	9	the	the	DET
fnp-2971	126	10	background	background	NOUN
fnp-2971	126	11	,	,	PUNCT
fnp-2971	126	12	few	few	ADJ
fnp-2971	126	13	small	small	ADJ
fnp-2971	126	14	myelinated	myelinated	ADJ
fnp-2971	126	15	axons	axon	NOUN
fnp-2971	126	16	,	,	PUNCT
fnp-2971	126	17	a	a	DET
fnp-2971	126	18	moderate	moderate	ADJ
fnp-2971	126	19	number	number	NOUN
fnp-2971	126	20	of	of	ADP
fnp-2971	126	21	oligodendrocytes	oligodendrocyte	NOUN
fnp-2971	126	22	,	,	PUNCT
fnp-2971	126	23	and	and	CCONJ
fnp-2971	126	24	mild	mild	ADJ
fnp-2971	126	25	to	to	ADP
fnp-2971	126	26	moderate	moderate	ADJ
fnp-2971	126	27	gliosis	gliosis	NOUN
fnp-2971	126	28	(	(	PUNCT
fnp-2971	126	29	figure	figure	VERB
fnp-2971	126	30	4c	4c	NOUN
fnp-2971	126	31	–	–	PUNCT
fnp-2971	126	32	e	e	NOUN
fnp-2971	126	33	)	)	PUNCT
fnp-2971	126	34	along	along	ADP
fnp-2971	126	35	with	with	ADP
fnp-2971	126	36	rarefied	rarefied	ADJ
fnp-2971	126	37	areas	area	NOUN
fnp-2971	126	38	showing	show	VERB
fnp-2971	126	39	a	a	DET
fnp-2971	126	40	marked	mark	VERB
fnp-2971	126	41	loss	loss	NOUN
fnp-2971	126	42	of	of	ADP
fnp-2971	126	43	oligodendrocytes	oligodendrocyte	NOUN
fnp-2971	126	44	and	and	CCONJ
fnp-2971	126	45	moderate	moderate	ADJ
fnp-2971	126	46	gliosis	gliosis	NOUN
fnp-2971	126	47	(	(	PUNCT
fnp-2971	126	48	figure	figure	NOUN
fnp-2971	126	49	4	4	NUM
fnp-2971	126	50	g	g	NOUN
fnp-2971	126	51	)	)	PUNCT
fnp-2971	126	52	.	.	PUNCT
fnp-2971	127	1	hla	hla	PROPN
fnp-2971	127	2	-	-	PUNCT
fnp-2971	127	3	dr	dr	PROPN
fnp-2971	127	4	immunostaining	immunostaining	NOUN
fnp-2971	127	5	highlighted	highlight	VERB
fnp-2971	127	6	dense	dense	ADJ
fnp-2971	127	7	(	(	PUNCT
fnp-2971	127	8	score	score	NOUN
fnp-2971	127	9	3	3	NUM
fnp-2971	127	10	)	)	PUNCT
fnp-2971	127	11	ramified	ramify	VERB
fnp-2971	127	12	microglia	microglia	NOUN
fnp-2971	127	13	in	in	ADP
fnp-2971	127	14	the	the	DET
fnp-2971	127	15	areas	area	NOUN
fnp-2971	127	16	showing	show	VERB
fnp-2971	127	17	higher	high	ADJ
fnp-2971	127	18	white	white	ADJ
fnp-2971	127	19	matter	matter	NOUN
fnp-2971	127	20	preservation	preservation	NOUN
fnp-2971	127	21	and	and	CCONJ
fnp-2971	127	22	in	in	ADP
fnp-2971	127	23	the	the	DET
fnp-2971	127	24	relatively	relatively	ADV
fnp-2971	127	25	preserved	preserve	VERB
fnp-2971	127	26	myelinated	myelinated	ADJ
fnp-2971	127	27	subcortical	subcortical	ADJ
fnp-2971	127	28	u	u	NOUN
fnp-2971	127	29	-	-	NOUN
fnp-2971	127	30	fibers	fiber	NOUN
fnp-2971	127	31	(	(	PUNCT
fnp-2971	127	32	figure	figure	NOUN
fnp-2971	127	33	4b	4b	PROPN
fnp-2971	127	34	,	,	PUNCT
fnp-2971	127	35	d	d	PROPN
fnp-2971	127	36	,	,	PUNCT
fnp-2971	127	37	f	f	PROPN
fnp-2971	127	38	)	)	PUNCT
fnp-2971	127	39	,	,	PUNCT
fnp-2971	127	40	while	while	SCONJ
fnp-2971	127	41	rarefied	rarefied	ADJ
fnp-2971	127	42	areas	area	NOUN
fnp-2971	127	43	showed	show	VERB
fnp-2971	127	44	no	no	DET
fnp-2971	127	45	ramified	ramified	ADJ
fnp-2971	127	46	microglia	microglia	NOUN
fnp-2971	127	47	(	(	PUNCT
fnp-2971	127	48	score	score	NOUN
fnp-2971	127	49	0	0	NUM
fnp-2971	127	50	)	)	PUNCT
fnp-2971	127	51	and	and	CCONJ
fnp-2971	127	52	a	a	DET
fnp-2971	127	53	few	few	ADJ
fnp-2971	127	54	to	to	PART
fnp-2971	127	55	moderate	moderate	VERB
fnp-2971	127	56	(	(	PUNCT
fnp-2971	127	57	score	score	NOUN
fnp-2971	127	58	1–2	1–2	NUM
fnp-2971	127	59	)	)	PUNCT
fnp-2971	127	60	amoeboid	amoeboid	ADJ
fnp-2971	127	61	microglia	microglia	NOUN
fnp-2971	127	62	(	(	PUNCT
fnp-2971	127	63	figure	figure	NOUN
fnp-2971	127	64	4h	4h	NUM
fnp-2971	127	65	)	)	PUNCT
fnp-2971	127	66	.	.	PUNCT
fnp-2971	128	1	axonal	axonal	ADJ
fnp-2971	128	2	spheroids	spheroid	NOUN
fnp-2971	128	3	were	be	AUX
fnp-2971	128	4	absent	absent	ADJ
fnp-2971	128	5	(	(	PUNCT
fnp-2971	128	6	score	score	NOUN
fnp-2971	128	7	0	0	NUM
fnp-2971	128	8	)	)	PUNCT
fnp-2971	128	9	in	in	ADP
fnp-2971	128	10	most	most	ADJ
fnp-2971	128	11	areas	area	NOUN
fnp-2971	128	12	,	,	PUNCT
fnp-2971	128	13	yet	yet	ADV
fnp-2971	128	14	scattered	scatter	VERB
fnp-2971	128	15	and	and	CCONJ
fnp-2971	128	16	rare	rare	ADJ
fnp-2971	128	17	(	(	PUNCT
fnp-2971	128	18	score	score	NOUN
fnp-2971	128	19	1	1	NUM
fnp-2971	128	20	)	)	PUNCT
fnp-2971	128	21	in	in	ADP
fnp-2971	128	22	others	other	NOUN
fnp-2971	128	23	.	.	PUNCT
fnp-2971	129	1	unfortunately	unfortunately	ADV
fnp-2971	129	2	,	,	PUNCT
fnp-2971	129	3	the	the	DET
fnp-2971	129	4	imaging	imaging	NOUN
fnp-2971	129	5	characteristics	characteristic	NOUN
fnp-2971	129	6	are	be	AUX
fnp-2971	129	7	not	not	PART
fnp-2971	129	8	available	available	ADJ
fnp-2971	129	9	for	for	ADP
fnp-2971	129	10	the	the	DET
fnp-2971	129	11	radiological	radiological	ADJ
fnp-2971	129	12	-	-	PUNCT
fnp-2971	129	13	pathological	pathological	ADJ
fnp-2971	129	14	correlation	correlation	NOUN
fnp-2971	129	15	.	.	PUNCT
fnp-2971	130	1	in	in	ADP
fnp-2971	130	2	general	general	ADJ
fnp-2971	130	3	,	,	PUNCT
fnp-2971	130	4	stage	stage	NOUN
fnp-2971	130	5	3	3	NUM
fnp-2971	130	6	pathology	pathology	NOUN
fnp-2971	130	7	,	,	PUNCT
fnp-2971	130	8	which	which	PRON
fnp-2971	130	9	denotes	denote	VERB
fnp-2971	130	10	long	long	ADV
fnp-2971	130	11	-	-	PUNCT
fnp-2971	130	12	standing	stand	VERB
fnp-2971	130	13	lesions	lesion	NOUN
fnp-2971	130	14	,	,	PUNCT
fnp-2971	130	15	are	be	AUX
fnp-2971	130	16	prominent	prominent	ADJ
fnp-2971	130	17	in	in	ADP
fnp-2971	130	18	frontal	frontal	ADJ
fnp-2971	130	19	and	and	CCONJ
fnp-2971	130	20	temporal	temporal	ADJ
fnp-2971	130	21	lobes	lobe	NOUN
fnp-2971	130	22	,	,	PUNCT
fnp-2971	130	23	less	less	ADV
fnp-2971	130	24	prominent	prominent	ADJ
fnp-2971	130	25	in	in	ADP
fnp-2971	130	26	parietal	parietal	ADJ
fnp-2971	130	27	lobes	lobe	NOUN
fnp-2971	130	28	,	,	PUNCT
fnp-2971	130	29	and	and	CCONJ
fnp-2971	130	30	rare	rare	ADJ
fnp-2971	130	31	in	in	ADP
fnp-2971	130	32	occipital	occipital	ADJ
fnp-2971	130	33	lobes	lobe	NOUN
fnp-2971	130	34	.	.	PUNCT
fnp-2971	131	1	discussion	discussion	NOUN
fnp-2971	131	2	axonal	axonal	ADJ
fnp-2971	131	3	spheroids	spheroid	NOUN
fnp-2971	131	4	and	and	CCONJ
fnp-2971	131	5	ramified	ramify	VERB
fnp-2971	131	6	microglia	microglia	NOUN
fnp-2971	131	7	we	we	PRON
fnp-2971	131	8	found	find	VERB
fnp-2971	131	9	a	a	DET
fnp-2971	131	10	strong	strong	ADJ
fnp-2971	131	11	association	association	NOUN
fnp-2971	131	12	between	between	ADP
fnp-2971	131	13	the	the	DET
fnp-2971	131	14	presence	presence	NOUN
fnp-2971	131	15	of	of	ADP
fnp-2971	131	16	axonal	axonal	ADJ
fnp-2971	131	17	spheroids	spheroid	NOUN
fnp-2971	131	18	and	and	CCONJ
fnp-2971	131	19	a	a	DET
fnp-2971	131	20	complete	complete	ADJ
fnp-2971	131	21	loss	loss	NOUN
fnp-2971	131	22	of	of	ADP
fnp-2971	131	23	ramified	ramified	ADJ
fnp-2971	131	24	microglia	microglia	NOUN
fnp-2971	131	25	in	in	ADP
fnp-2971	131	26	all	all	DET
fnp-2971	131	27	pathological	pathological	ADJ
fnp-2971	131	28	stages	stage	NOUN
fnp-2971	131	29	of	of	ADP
fnp-2971	131	30	alas	alas	DET
fnp-2971	131	31	lesions	lesion	NOUN
fnp-2971	131	32	.	.	PUNCT
fnp-2971	132	1	this	this	DET
fnp-2971	132	2	association	association	NOUN
fnp-2971	132	3	was	be	AUX
fnp-2971	132	4	also	also	ADV
fnp-2971	132	5	apparent	apparent	ADJ
fnp-2971	132	6	in	in	ADP
fnp-2971	132	7	very	very	ADV
fnp-2971	132	8	small	small	ADJ
fnp-2971	132	9	areas	area	NOUN
fnp-2971	132	10	with	with	ADP
fnp-2971	132	11	frequent	frequent	ADJ
fnp-2971	132	12	axonal	axonal	ADJ
fnp-2971	132	13	spheroids	spheroid	NOUN
fnp-2971	132	14	and	and	CCONJ
fnp-2971	132	15	in	in	ADP
fnp-2971	132	16	focal	focal	ADJ
fnp-2971	132	17	cortical	cortical	ADJ
fnp-2971	132	18	lesions	lesion	NOUN
fnp-2971	132	19	,	,	PUNCT
fnp-2971	132	20	strengthening	strengthen	VERB
fnp-2971	132	21	the	the	DET
fnp-2971	132	22	reliability	reliability	NOUN
fnp-2971	132	23	of	of	ADP
fnp-2971	132	24	the	the	DET
fnp-2971	132	25	findings	finding	NOUN
fnp-2971	132	26	.	.	PUNCT
fnp-2971	133	1	although	although	SCONJ
fnp-2971	133	2	this	this	PRON
fnp-2971	133	3	was	be	AUX
fnp-2971	133	4	a	a	DET
fnp-2971	133	5	semi	semi	ADJ
fnp-2971	133	6	-	-	ADJ
fnp-2971	133	7	quantitative	quantitative	ADJ
fnp-2971	133	8	study	study	NOUN
fnp-2971	133	9	,	,	PUNCT
fnp-2971	133	10	our	our	PRON
fnp-2971	133	11	findings	finding	NOUN
fnp-2971	133	12	demonstrate	demonstrate	VERB
fnp-2971	133	13	a	a	DET
fnp-2971	133	14	strong	strong	ADJ
fnp-2971	133	15	correlation	correlation	NOUN
fnp-2971	133	16	between	between	ADP
fnp-2971	133	17	the	the	DET
fnp-2971	133	18	complete	complete	ADJ
fnp-2971	133	19	absence	absence	NOUN
fnp-2971	133	20	of	of	ADP
fnp-2971	133	21	ramified	ramified	ADJ
fnp-2971	133	22	microglia	microglia	NOUN
fnp-2971	133	23	(	(	PUNCT
fnp-2971	133	24	score	score	NOUN
fnp-2971	133	25	0	0	NUM
fnp-2971	133	26	)	)	PUNCT
fnp-2971	133	27	and	and	CCONJ
fnp-2971	133	28	the	the	DET
fnp-2971	133	29	presence	presence	NOUN
fnp-2971	133	30	of	of	ADP
fnp-2971	133	31	axonal	axonal	ADJ
fnp-2971	133	32	spheroids	spheroid	NOUN
fnp-2971	133	33	in	in	ADP
fnp-2971	133	34	affected	affected	ADJ
fnp-2971	133	35	areas	area	NOUN
fnp-2971	133	36	.	.	PUNCT
fnp-2971	134	1	this	this	DET
fnp-2971	134	2	finding	finding	NOUN
fnp-2971	134	3	could	could	AUX
fnp-2971	134	4	be	be	AUX
fnp-2971	134	5	considered	consider	VERB
fnp-2971	134	6	“	"	PUNCT
fnp-2971	134	7	quantitative	quantitative	ADJ
fnp-2971	134	8	”	"	PUNCT
fnp-2971	134	9	,	,	PUNCT
fnp-2971	134	10	as	as	SCONJ
fnp-2971	134	11	score	score	NOUN
fnp-2971	134	12	0	0	NUM
fnp-2971	134	13	denotes	denote	VERB
fnp-2971	134	14	a	a	DET
fnp-2971	134	15	complete	complete	ADJ
fnp-2971	134	16	absence	absence	NOUN
fnp-2971	134	17	of	of	ADP
fnp-2971	134	18	the	the	DET
fnp-2971	134	19	ramified	ramified	ADJ
fnp-2971	134	20	microglia	microglia	NOUN
fnp-2971	134	21	.	.	PUNCT
fnp-2971	135	1	in	in	ADP
fnp-2971	135	2	stage	stage	NOUN
fnp-2971	135	3	3	3	NUM
fnp-2971	135	4	,	,	PUNCT
fnp-2971	135	5	the	the	DET
fnp-2971	135	6	presence	presence	NOUN
fnp-2971	135	7	of	of	ADP
fnp-2971	135	8	ramified	ramified	ADJ
fnp-2971	135	9	microglia	microglia	NOUN
fnp-2971	135	10	was	be	AUX
fnp-2971	135	11	associated	associate	VERB
fnp-2971	135	12	with	with	ADP
fnp-2971	135	13	areas	area	NOUN
fnp-2971	135	14	of	of	ADP
fnp-2971	135	15	better	well	ADJ
fnp-2971	135	16	white	white	ADJ
fnp-2971	135	17	matter	matter	NOUN
fnp-2971	135	18	preservation	preservation	NOUN
fnp-2971	135	19	.	.	PUNCT
fnp-2971	136	1	these	these	DET
fnp-2971	136	2	findings	finding	NOUN
fnp-2971	136	3	provide	provide	VERB
fnp-2971	136	4	a	a	DET
fnp-2971	136	5	link	link	NOUN
fnp-2971	136	6	between	between	ADP
fnp-2971	136	7	pathological	pathological	ADJ
fnp-2971	136	8	features	feature	NOUN
fnp-2971	136	9	observed	observe	VERB
fnp-2971	136	10	(	(	PUNCT
fnp-2971	136	11	i.e.	i.e.	X
fnp-2971	136	12	axonopathy	axonopathy	ADJ
fnp-2971	136	13	)	)	PUNCT
fnp-2971	136	14	and	and	CCONJ
fnp-2971	136	15	the	the	DET
fnp-2971	136	16	genetic	genetic	ADJ
fnp-2971	136	17	abnormality	abnormality	NOUN
fnp-2971	136	18	identified	identify	VERB
fnp-2971	136	19	(	(	PUNCT
fnp-2971	136	20	i.e.	i.e.	X
fnp-2971	136	21	microgliopathy	microgliopathy	NOUN
fnp-2971	136	22	)	)	PUNCT
fnp-2971	136	23	in	in	ADP
fnp-2971	136	24	alas	ala	NOUN
fnp-2971	136	25	,	,	PUNCT
fnp-2971	136	26	supporting	support	VERB
fnp-2971	136	27	the	the	DET
fnp-2971	136	28	beneficial	beneficial	ADJ
fnp-2971	136	29	effects	effect	NOUN
fnp-2971	136	30	of	of	ADP
fnp-2971	136	31	the	the	DET
fnp-2971	136	32	reactive	reactive	NOUN
fnp-2971	136	33	ramified	ramify	VERB
fnp-2971	136	34	microglia	microglia	NOUN
fnp-2971	136	35	in	in	ADP
fnp-2971	136	36	maintaining	maintain	VERB
fnp-2971	136	37	axonal	axonal	ADJ
fnp-2971	136	38	integrity	integrity	NOUN
fnp-2971	136	39	.	.	PUNCT
fnp-2971	137	1	csf1r	csf1r	PROPN
fnp-2971	137	2	and	and	CCONJ
fnp-2971	137	3	alas	alas	PRON
fnp-2971	137	4	identifying	identify	VERB
fnp-2971	137	5	csf1r	csf1r	PROPN
fnp-2971	137	6	mutations	mutation	NOUN
fnp-2971	137	7	as	as	ADP
fnp-2971	137	8	the	the	DET
fnp-2971	137	9	underlying	underlying	ADJ
fnp-2971	137	10	genetic	genetic	ADJ
fnp-2971	137	11	abnormality	abnormality	NOUN
fnp-2971	137	12	in	in	ADP
fnp-2971	137	13	alas	alas	PRON
fnp-2971	137	14	suggested	suggest	VERB
fnp-2971	137	15	microgliopathy	microgliopathy	ADJ
fnp-2971	137	16	as	as	ADP
fnp-2971	137	17	the	the	DET
fnp-2971	137	18	underlying	underlying	ADJ
fnp-2971	137	19	abnormality	abnormality	NOUN
fnp-2971	137	20	(	(	PUNCT
fnp-2971	137	21	3	3	NUM
fnp-2971	137	22	,	,	PUNCT
fnp-2971	137	23	12	12	NUM
fnp-2971	137	24	)	)	PUNCT
fnp-2971	137	25	in	in	ADP
fnp-2971	137	26	alas	alas	INTJ
fnp-2971	137	27	.	.	PUNCT
fnp-2971	138	1	as	as	SCONJ
fnp-2971	138	2	it	it	PRON
fnp-2971	138	3	is	be	AUX
fnp-2971	138	4	the	the	DET
fnp-2971	138	5	most	most	ADV
fnp-2971	138	6	common	common	ADJ
fnp-2971	138	7	mutation	mutation	NOUN
fnp-2971	138	8	in	in	ADP
fnp-2971	138	9	alas	alas	PROPN
fnp-2971	138	10	,	,	PUNCT
fnp-2971	138	11	konno	konno	PROPN
fnp-2971	138	12	et	et	PROPN
fnp-2971	138	13	al	al	PROPN
fnp-2971	138	14	.	.	PROPN
fnp-2971	138	15	proposed	propose	VERB
fnp-2971	138	16	the	the	DET
fnp-2971	138	17	term	term	NOUN
fnp-2971	138	18	“	"	PUNCT
fnp-2971	138	19	csf1r	csf1r	NOUN
fnp-2971	138	20	-	-	PUNCT
fnp-2971	138	21	related	relate	VERB
fnp-2971	138	22	leukoencephalopathy	leukoencephalopathy	NOUN
fnp-2971	138	23	”	"	PUNCT
fnp-2971	138	24	for	for	ADP
fnp-2971	138	25	this	this	DET
fnp-2971	138	26	entity	entity	NOUN
fnp-2971	138	27	(	(	PUNCT
fnp-2971	138	28	13	13	NUM
fnp-2971	138	29	)	)	PUNCT
fnp-2971	138	30	.	.	PUNCT
fnp-2971	139	1	as	as	SCONJ
fnp-2971	139	2	the	the	DET
fnp-2971	139	3	pathological	pathological	ADJ
fnp-2971	139	4	features	feature	NOUN
fnp-2971	139	5	are	be	AUX
fnp-2971	139	6	the	the	DET
fnp-2971	139	7	gold	gold	ADJ
fnp-2971	139	8	standard	standard	NOUN
fnp-2971	139	9	for	for	ADP
fnp-2971	139	10	alas	alas	DET
fnp-2971	139	11	diagnosis	diagnosis	NOUN
fnp-2971	139	12	and	and	CCONJ
fnp-2971	139	13	not	not	PART
fnp-2971	139	14	all	all	PRON
fnp-2971	139	15	alas	alas	DET
fnp-2971	139	16	cases	case	NOUN
fnp-2971	139	17	have	have	VERB
fnp-2971	139	18	csf1r	csf1r	PROPN
fnp-2971	139	19	alterations	alteration	NOUN
fnp-2971	139	20	,	,	PUNCT
fnp-2971	139	21	this	this	DET
fnp-2971	139	22	term	term	NOUN
fnp-2971	139	23	would	would	AUX
fnp-2971	139	24	be	be	AUX
fnp-2971	139	25	specific	specific	ADJ
fnp-2971	139	26	to	to	ADP
fnp-2971	139	27	cases	case	NOUN
fnp-2971	139	28	with	with	ADP
fnp-2971	139	29	confirmed	confirm	VERB
fnp-2971	139	30	csf1r	csf1r	PROPN
fnp-2971	139	31	mutations	mutation	NOUN
fnp-2971	139	32	only	only	ADV
fnp-2971	139	33	and	and	CCONJ
fnp-2971	139	34	would	would	AUX
fnp-2971	139	35	not	not	PART
fnp-2971	139	36	be	be	AUX
fnp-2971	139	37	suitable	suitable	ADJ
fnp-2971	139	38	for	for	ADP
fnp-2971	139	39	all	all	PRON
fnp-2971	139	40	alas	alas	DET
fnp-2971	139	41	cases	case	NOUN
fnp-2971	139	42	.	.	PUNCT
fnp-2971	140	1	aars2	aars2	NOUN
fnp-2971	140	2	mutations	mutation	NOUN
fnp-2971	140	3	have	have	AUX
fnp-2971	140	4	been	be	AUX
fnp-2971	140	5	described	describe	VERB
fnp-2971	140	6	in	in	ADP
fnp-2971	140	7	cases	case	NOUN
fnp-2971	140	8	suspected	suspect	VERB
fnp-2971	140	9	to	to	PART
fnp-2971	140	10	represent	represent	VERB
fnp-2971	140	11	alas	ala	NOUN
fnp-2971	140	12	,	,	PUNCT
fnp-2971	140	13	including	include	VERB
fnp-2971	140	14	one	one	NUM
fnp-2971	140	15	case	case	NOUN
fnp-2971	140	16	with	with	ADP
fnp-2971	140	17	biopsy	biopsy	NOUN
fnp-2971	140	18	findings	finding	NOUN
fnp-2971	140	19	supportive	supportive	ADJ
fnp-2971	140	20	of	of	ADP
fnp-2971	140	21	this	this	DET
fnp-2971	140	22	diagnosis	diagnosis	NOUN
fnp-2971	140	23	(	(	PUNCT
fnp-2971	140	24	14	14	NUM
fnp-2971	140	25	)	)	PUNCT
fnp-2971	140	26	.	.	PUNCT
fnp-2971	141	1	however	however	ADV
fnp-2971	141	2	,	,	PUNCT
fnp-2971	141	3	we	we	PRON
fnp-2971	141	4	concur	concur	VERB
fnp-2971	141	5	with	with	ADP
fnp-2971	141	6	konno	konno	PROPN
fnp-2971	141	7	et	et	PROPN
fnp-2971	141	8	al	al	PROPN
fnp-2971	141	9	.	.	PUNCT
fnp-2971	142	1	that	that	SCONJ
fnp-2971	142	2	“	"	PUNCT
fnp-2971	142	3	further	further	ADJ
fnp-2971	142	4	studies	study	NOUN
fnp-2971	142	5	,	,	PUNCT
fnp-2971	142	6	including	include	VERB
fnp-2971	142	7	detailed	detailed	ADJ
fnp-2971	142	8	analyses	analysis	NOUN
fnp-2971	142	9	of	of	ADP
fnp-2971	142	10	autopsied	autopsie	VERB
fnp-2971	142	11	brains	brain	NOUN
fnp-2971	142	12	,	,	PUNCT
fnp-2971	142	13	are	be	AUX
fnp-2971	142	14	required	require	VERB
fnp-2971	142	15	to	to	PART
fnp-2971	142	16	characterize	characterize	VERB
fnp-2971	142	17	aars2	aars2	NOUN
fnp-2971	142	18	associated	associate	VERB
fnp-2971	142	19	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	142	20	”	"	PUNCT
fnp-2971	142	21	(	(	PUNCT
fnp-2971	142	22	13	13	NUM
fnp-2971	142	23	)	)	PUNCT
fnp-2971	142	24	.	.	PUNCT
fnp-2971	143	1	csf1r	csf1r	PROPN
fnp-2971	143	2	is	be	AUX
fnp-2971	143	3	a	a	DET
fnp-2971	143	4	tyrosine	tyrosine	NOUN
fnp-2971	143	5	kinase	kinase	NOUN
fnp-2971	143	6	receptor	receptor	NOUN
fnp-2971	143	7	whose	whose	DET
fnp-2971	143	8	signaling	signal	VERB
fnp-2971	143	9	is	be	AUX
fnp-2971	143	10	fundamental	fundamental	ADJ
fnp-2971	143	11	for	for	ADP
fnp-2971	143	12	microglial	microglial	ADJ
fnp-2971	143	13	survival	survival	NOUN
fnp-2971	143	14	(	(	PUNCT
fnp-2971	143	15	15	15	NUM
fnp-2971	143	16	)	)	PUNCT
fnp-2971	143	17	.	.	PUNCT
fnp-2971	144	1	two	two	NUM
fnp-2971	144	2	different	different	ADJ
fnp-2971	144	3	mechanisms	mechanism	NOUN
fnp-2971	144	4	have	have	AUX
fnp-2971	144	5	been	be	AUX
fnp-2971	144	6	proposed	propose	VERB
fnp-2971	144	7	for	for	SCONJ
fnp-2971	144	8	csf1r	csf1r	PROPN
fnp-2971	144	9	mutations	mutation	NOUN
fnp-2971	144	10	to	to	PART
fnp-2971	144	11	affect	affect	VERB
fnp-2971	144	12	the	the	DET
fnp-2971	144	13	function	function	NOUN
fnp-2971	144	14	of	of	ADP
fnp-2971	144	15	microglia	microglia	NOUN
fnp-2971	144	16	in	in	ADP
fnp-2971	144	17	patients	patient	NOUN
fnp-2971	144	18	with	with	ADP
fnp-2971	144	19	alas	alas	PRON
fnp-2971	144	20	:	:	PUNCT
fnp-2971	144	21	1	1	NUM
fnp-2971	144	22	)	)	PUNCT
fnp-2971	144	23	haploinsufficiency	haploinsufficiency	NOUN
fnp-2971	144	24	mechanism	mechanism	NOUN
fnp-2971	144	25	that	that	PRON
fnp-2971	144	26	results	result	VERB
fnp-2971	144	27	in	in	ADP
fnp-2971	144	28	a	a	DET
fnp-2971	144	29	loss	loss	NOUN
fnp-2971	144	30	of	of	ADP
fnp-2971	144	31	function	function	NOUN
fnp-2971	144	32	of	of	ADP
fnp-2971	144	33	csf1r	csf1r	X
fnp-2971	144	34	(	(	PUNCT
fnp-2971	144	35	8	8	NUM
fnp-2971	144	36	,	,	PUNCT
fnp-2971	144	37	16	16	NUM
fnp-2971	144	38	,	,	PUNCT
fnp-2971	144	39	17	17	NUM
fnp-2971	144	40	)	)	PUNCT
fnp-2971	144	41	,	,	PUNCT
fnp-2971	144	42	and	and	CCONJ
fnp-2971	144	43	2	2	X
fnp-2971	144	44	)	)	PUNCT
fnp-2971	144	45	a	a	DET
fnp-2971	144	46	dominant	dominant	ADJ
fnp-2971	144	47	-	-	PUNCT
fnp-2971	144	48	negative	negative	ADJ
fnp-2971	144	49	model	model	NOUN
fnp-2971	144	50	(	(	PUNCT
fnp-2971	144	51	18	18	NUM
fnp-2971	144	52	)	)	PUNCT
fnp-2971	144	53	.	.	PUNCT
fnp-2971	145	1	it	it	PRON
fnp-2971	145	2	is	be	AUX
fnp-2971	145	3	still	still	ADV
fnp-2971	145	4	unclear	unclear	ADJ
fnp-2971	145	5	what	what	PRON
fnp-2971	145	6	the	the	DET
fnp-2971	145	7	lost	lose	VERB
fnp-2971	145	8	functions	function	NOUN
fnp-2971	145	9	are	be	AUX
fnp-2971	145	10	or	or	CCONJ
fnp-2971	145	11	what	what	PRON
fnp-2971	145	12	is	be	AUX
fnp-2971	145	13	constitutive	constitutive	ADJ
fnp-2971	145	14	of	of	ADP
fnp-2971	145	15	the	the	DET
fnp-2971	145	16	dominant	dominant	ADJ
fnp-2971	145	17	-	-	PUNCT
fnp-2971	145	18	negative	negative	ADJ
fnp-2971	145	19	effect	effect	NOUN
fnp-2971	145	20	on	on	ADP
fnp-2971	145	21	the	the	DET
fnp-2971	145	22	microglia	microglia	NOUN
fnp-2971	145	23	.	.	PUNCT
fnp-2971	146	1	oosterhof	oosterhof	PROPN
fnp-2971	146	2	et	et	PROPN
fnp-2971	146	3	al	al	PROPN
fnp-2971	146	4	.	.	PROPN
fnp-2971	146	5	concluded	conclude	VERB
fnp-2971	146	6	that	that	SCONJ
fnp-2971	146	7	the	the	DET
fnp-2971	146	8	haploinsufficiency	haploinsufficiency	NOUN
fnp-2971	146	9	resulted	result	VERB
fnp-2971	146	10	in	in	ADP
fnp-2971	146	11	the	the	DET
fnp-2971	146	12	maldistribution	maldistribution	NOUN
fnp-2971	146	13	of	of	ADP
fnp-2971	146	14	microglia	microglia	NOUN
fnp-2971	146	15	that	that	PRON
fnp-2971	146	16	leads	lead	VERB
fnp-2971	146	17	to	to	ADP
fnp-2971	146	18	their	their	PRON
fnp-2971	146	19	local	local	ADJ
fnp-2971	146	20	loss	loss	NOUN
fnp-2971	146	21	(	(	PUNCT
fnp-2971	146	22	8)	8)	NUM
fnp-2971	146	23	.	.	PUNCT
fnp-2971	147	1	their	their	PRON
fnp-2971	147	2	recent	recent	ADJ
fnp-2971	147	3	work	work	NOUN
fnp-2971	147	4	showed	show	VERB
fnp-2971	147	5	that	that	SCONJ
fnp-2971	147	6	homozygous	homozygous	ADJ
fnp-2971	147	7	mutations	mutation	NOUN
fnp-2971	147	8	in	in	ADP
fnp-2971	147	9	csf1r	csf1r	PROPN
fnp-2971	147	10	could	could	AUX
fnp-2971	147	11	result	result	VERB
fnp-2971	147	12	in	in	ADP
fnp-2971	147	13	the	the	DET
fnp-2971	147	14	complete	complete	ADJ
fnp-2971	147	15	absence	absence	NOUN
fnp-2971	147	16	of	of	ADP
fnp-2971	147	17	microglia	microglia	NOUN
fnp-2971	147	18	in	in	ADP
fnp-2971	147	19	pediatric	pediatric	ADJ
fnp-2971	147	20	-	-	PUNCT
fnp-2971	147	21	onset	onset	NOUN
fnp-2971	147	22	leukodystrophy	leukodystrophy	NOUN
fnp-2971	147	23	(	(	PUNCT
fnp-2971	147	24	19	19	NUM
fnp-2971	147	25	)	)	PUNCT
fnp-2971	147	26	.	.	PUNCT
fnp-2971	148	1	our	our	PRON
fnp-2971	148	2	results	result	NOUN
fnp-2971	148	3	confirmed	confirm	VERB
fnp-2971	148	4	the	the	DET
fnp-2971	148	5	regional	regional	ADJ
fnp-2971	148	6	loss	loss	NOUN
fnp-2971	148	7	of	of	ADP
fnp-2971	148	8	ramified	ramified	ADJ
fnp-2971	148	9	microglia	microglia	NOUN
fnp-2971	148	10	in	in	ADP
fnp-2971	148	11	alas	alas	PRON
fnp-2971	148	12	and	and	CCONJ
fnp-2971	148	13	found	find	VERB
fnp-2971	148	14	that	that	SCONJ
fnp-2971	148	15	the	the	DET
fnp-2971	148	16	axonal	axonal	ADJ
fnp-2971	148	17	pathology	pathology	NOUN
fnp-2971	148	18	is	be	AUX
fnp-2971	148	19	mostly	mostly	ADV
fnp-2971	148	20	limited	limit	VERB
fnp-2971	148	21	to	to	ADP
fnp-2971	148	22	these	these	DET
fnp-2971	148	23	areas	area	NOUN
fnp-2971	148	24	,	,	PUNCT
fnp-2971	148	25	supporting	support	VERB
fnp-2971	148	26	the	the	DET
fnp-2971	148	27	importance	importance	NOUN
fnp-2971	148	28	of	of	ADP
fnp-2971	148	29	microglia	microglia	NOUN
fnp-2971	148	30	in	in	ADP
fnp-2971	148	31	alas	alas	INTJ
fnp-2971	148	32	’	'	PUNCT
fnp-2971	148	33	pathogenesis	pathogenesis	NOUN
fnp-2971	148	34	and	and	CCONJ
fnp-2971	148	35	suggesting	suggest	VERB
fnp-2971	148	36	a	a	DET
fnp-2971	148	37	protective	protective	ADJ
fnp-2971	148	38	role	role	NOUN
fnp-2971	148	39	of	of	ADP
fnp-2971	148	40	ramified	ramified	ADJ
fnp-2971	148	41	microglia	microglia	NOUN
fnp-2971	148	42	.	.	PUNCT
fnp-2971	149	1	figure	figure	NOUN
fnp-2971	149	2	4	4	NUM
fnp-2971	149	3	.	.	PUNCT
fnp-2971	149	4	microglia	microglia	ADJ
fnp-2971	149	5	and	and	CCONJ
fnp-2971	149	6	axonal	axonal	ADJ
fnp-2971	149	7	spheroids	spheroid	NOUN
fnp-2971	149	8	in	in	ADP
fnp-2971	149	9	stage	stage	NOUN
fnp-2971	149	10	3	3	NUM
fnp-2971	149	11	pathology	pathology	NOUN
fnp-2971	149	12	.	.	PUNCT
fnp-2971	150	1	(	(	PUNCT
fnp-2971	150	2	a	a	X
fnp-2971	150	3	)	)	PUNCT
fnp-2971	150	4	marked	mark	VERB
fnp-2971	150	5	loss	loss	NOUN
fnp-2971	150	6	of	of	ADP
fnp-2971	150	7	myelinated	myelinated	ADJ
fnp-2971	150	8	fibers	fiber	NOUN
fnp-2971	150	9	in	in	ADP
fnp-2971	150	10	the	the	DET
fnp-2971	150	11	deep	deep	ADJ
fnp-2971	150	12	white	white	ADJ
fnp-2971	150	13	matter	matter	NOUN
fnp-2971	150	14	with	with	ADP
fnp-2971	150	15	relative	relative	ADJ
fnp-2971	150	16	preservation	preservation	NOUN
fnp-2971	150	17	of	of	ADP
fnp-2971	150	18	the	the	DET
fnp-2971	150	19	subcortical	subcortical	ADJ
fnp-2971	150	20	u	u	NOUN
fnp-2971	150	21	-	-	NOUN
fnp-2971	150	22	fibers	fiber	NOUN
fnp-2971	150	23	(	(	PUNCT
fnp-2971	150	24	lfb	lfb	PROPN
fnp-2971	150	25	-	-	PUNCT
fnp-2971	150	26	he	he	PRON
fnp-2971	150	27	;	;	PUNCT
fnp-2971	150	28	scale	scale	NOUN
fnp-2971	150	29	bar	bar	NOUN
fnp-2971	150	30	:	:	PUNCT
fnp-2971	150	31	5	5	NUM
fnp-2971	150	32	mm	mm	NOUN
fnp-2971	150	33	)	)	PUNCT
fnp-2971	150	34	.	.	PUNCT
fnp-2971	151	1	(	(	PUNCT
fnp-2971	151	2	b	b	X
fnp-2971	151	3	)	)	PUNCT
fnp-2971	151	4	variable	variable	ADJ
fnp-2971	151	5	degree	degree	NOUN
fnp-2971	151	6	of	of	ADP
fnp-2971	151	7	hla	hla	PROPN
fnp-2971	151	8	-	-	PUNCT
fnp-2971	151	9	dr	dr	NOUN
fnp-2971	151	10	expression	expression	NOUN
fnp-2971	151	11	in	in	ADP
fnp-2971	151	12	the	the	DET
fnp-2971	151	13	subcortical	subcortical	ADJ
fnp-2971	151	14	deep	deep	ADJ
fnp-2971	151	15	white	white	ADJ
fnp-2971	151	16	matter	matter	NOUN
fnp-2971	151	17	with	with	ADP
fnp-2971	151	18	multifocal	multifocal	ADJ
fnp-2971	151	19	areas	area	NOUN
fnp-2971	151	20	containing	contain	VERB
fnp-2971	151	21	hla	hla	PROPN
fnp-2971	151	22	-	-	PUNCT
fnp-2971	151	23	dr	dr	NOUN
fnp-2971	151	24	-	-	PUNCT
fnp-2971	151	25	expressing	express	VERB
fnp-2971	151	26	ramified	ramified	ADJ
fnp-2971	151	27	microglia	microglia	NOUN
fnp-2971	151	28	.	.	PUNCT
fnp-2971	152	1	these	these	DET
fnp-2971	152	2	areas	area	NOUN
fnp-2971	152	3	are	be	AUX
fnp-2971	152	4	found	find	VERB
fnp-2971	152	5	mainly	mainly	ADV
fnp-2971	152	6	in	in	ADP
fnp-2971	152	7	the	the	DET
fnp-2971	152	8	subcortical	subcortical	ADJ
fnp-2971	152	9	u	u	NOUN
fnp-2971	152	10	-	-	NOUN
fnp-2971	152	11	fibers	fiber	NOUN
fnp-2971	152	12	and	and	CCONJ
fnp-2971	152	13	small	small	ADJ
fnp-2971	152	14	foci	focus	NOUN
fnp-2971	152	15	of	of	ADP
fnp-2971	152	16	the	the	DET
fnp-2971	152	17	adjacent	adjacent	ADJ
fnp-2971	152	18	white	white	ADJ
fnp-2971	152	19	matter	matter	NOUN
fnp-2971	152	20	.	.	PUNCT
fnp-2971	153	1	the	the	DET
fnp-2971	153	2	deeper	deep	ADJ
fnp-2971	153	3	white	white	ADJ
fnp-2971	153	4	matter	matter	NOUN
fnp-2971	153	5	shows	show	VERB
fnp-2971	153	6	only	only	ADV
fnp-2971	153	7	scattered	scatter	VERB
fnp-2971	153	8	hla	hla	PROPN
fnp-2971	153	9	-	-	PUNCT
fnp-2971	153	10	dr	dr	NOUN
fnp-2971	153	11	-	-	PUNCT
fnp-2971	153	12	expressing	express	VERB
fnp-2971	153	13	ramified	ramified	ADJ
fnp-2971	153	14	microglia	microglia	NOUN
fnp-2971	153	15	(	(	PUNCT
fnp-2971	153	16	hla	hla	PROPN
fnp-2971	153	17	-	-	PUNCT
fnp-2971	153	18	dr	dr	PROPN
fnp-2971	153	19	;	;	PUNCT
fnp-2971	153	20	scale	scale	NOUN
fnp-2971	153	21	bar	bar	NOUN
fnp-2971	153	22	:	:	PUNCT
fnp-2971	153	23	5	5	NUM
fnp-2971	153	24	mm	mm	NOUN
fnp-2971	153	25	)	)	PUNCT
fnp-2971	153	26	.	.	PUNCT
fnp-2971	154	1	(	(	PUNCT
fnp-2971	154	2	c	c	X
fnp-2971	154	3	)	)	PUNCT
fnp-2971	154	4	higher	high	ADJ
fnp-2971	154	5	magnification	magnification	NOUN
fnp-2971	154	6	of	of	ADP
fnp-2971	154	7	the	the	DET
fnp-2971	154	8	area	area	NOUN
fnp-2971	154	9	within	within	ADP
fnp-2971	154	10	the	the	DET
fnp-2971	154	11	lower	low	ADJ
fnp-2971	154	12	rectangle	rectangle	NOUN
fnp-2971	154	13	outlined	outline	VERB
fnp-2971	154	14	in	in	ADP
fnp-2971	154	15	(	(	PUNCT
fnp-2971	154	16	a	a	NOUN
fnp-2971	154	17	)	)	PUNCT
fnp-2971	154	18	.	.	PUNCT
fnp-2971	155	1	the	the	DET
fnp-2971	155	2	deep	deep	ADJ
fnp-2971	155	3	white	white	ADJ
fnp-2971	155	4	matter	matter	NOUN
fnp-2971	155	5	shows	show	VERB
fnp-2971	155	6	a	a	DET
fnp-2971	155	7	variable	variable	ADJ
fnp-2971	155	8	loss	loss	NOUN
fnp-2971	155	9	of	of	ADP
fnp-2971	155	10	myelinated	myelinated	ADJ
fnp-2971	155	11	fibers	fiber	NOUN
fnp-2971	155	12	.	.	PUNCT
fnp-2971	156	1	areas	area	NOUN
fnp-2971	156	2	of	of	ADP
fnp-2971	156	3	prominent	prominent	ADJ
fnp-2971	156	4	loss	loss	NOUN
fnp-2971	156	5	show	show	NOUN
fnp-2971	156	6	marked	mark	VERB
fnp-2971	156	7	rarefaction	rarefaction	NOUN
fnp-2971	156	8	,	,	PUNCT
fnp-2971	156	9	while	while	SCONJ
fnp-2971	156	10	areas	area	NOUN
fnp-2971	156	11	with	with	ADP
fnp-2971	156	12	better	well	ADV
fnp-2971	156	13	preserved	preserve	VERB
fnp-2971	156	14	myelinated	myelinated	ADJ
fnp-2971	156	15	fibers	fiber	NOUN
fnp-2971	156	16	in	in	ADP
fnp-2971	156	17	the	the	DET
fnp-2971	156	18	center	center	NOUN
fnp-2971	156	19	show	show	VERB
fnp-2971	156	20	a	a	DET
fnp-2971	156	21	more	more	ADV
fnp-2971	156	22	compact	compact	ADJ
fnp-2971	156	23	parenchyma	parenchyma	NOUN
fnp-2971	156	24	(	(	PUNCT
fnp-2971	156	25	lfb	lfb	PROPN
fnp-2971	156	26	-	-	PUNCT
fnp-2971	156	27	he	he	PRON
fnp-2971	156	28	;	;	PUNCT
fnp-2971	156	29	scale	scale	NOUN
fnp-2971	156	30	bar	bar	NOUN
fnp-2971	156	31	:	:	PUNCT
fnp-2971	156	32	500	500	NUM
fnp-2971	156	33	µm	µm	NUM
fnp-2971	156	34	)	)	PUNCT
fnp-2971	156	35	.	.	PUNCT
fnp-2971	157	1	(	(	PUNCT
fnp-2971	157	2	d	d	X
fnp-2971	157	3	)	)	PUNCT
fnp-2971	157	4	a	a	DET
fnp-2971	157	5	better	well	ADV
fnp-2971	157	6	-	-	PUNCT
fnp-2971	157	7	preserved	preserve	VERB
fnp-2971	157	8	central	central	ADJ
fnp-2971	157	9	area	area	NOUN
fnp-2971	157	10	in	in	ADP
fnp-2971	157	11	(	(	PUNCT
fnp-2971	157	12	c	c	X
fnp-2971	157	13	)	)	PUNCT
fnp-2971	157	14	shows	show	VERB
fnp-2971	157	15	a	a	DET
fnp-2971	157	16	marked	mark	VERB
fnp-2971	157	17	expression	expression	NOUN
fnp-2971	157	18	of	of	ADP
fnp-2971	157	19	hla	hla	PROPN
fnp-2971	157	20	-	-	PUNCT
fnp-2971	157	21	dr	dr	PROPN
fnp-2971	157	22	ramified	ramified	ADJ
fnp-2971	157	23	microglia	microglia	NOUN
fnp-2971	157	24	,	,	PUNCT
fnp-2971	157	25	while	while	SCONJ
fnp-2971	157	26	rarefied	rarefied	ADJ
fnp-2971	157	27	areas	area	NOUN
fnp-2971	157	28	show	show	VERB
fnp-2971	157	29	only	only	ADV
fnp-2971	157	30	scattered	scatter	VERB
fnp-2971	157	31	hla	hla	PROPN
fnp-2971	157	32	-	-	PUNCT
fnp-2971	157	33	dr	dr	NOUN
fnp-2971	157	34	-	-	PUNCT
fnp-2971	157	35	expressing	express	VERB
fnp-2971	157	36	ramified	ramified	ADJ
fnp-2971	157	37	microglia	microglia	NOUN
fnp-2971	157	38	and	and	CCONJ
fnp-2971	157	39	moderate	moderate	ADJ
fnp-2971	157	40	to	to	ADP
fnp-2971	157	41	frequent	frequent	ADJ
fnp-2971	157	42	hla	hla	PROPN
fnp-2971	157	43	-	-	PUNCT
fnp-2971	157	44	dr	dr	NOUN
fnp-2971	157	45	-	-	PUNCT
fnp-2971	157	46	expressing	express	VERB
fnp-2971	157	47	cells	cell	NOUN
fnp-2971	157	48	with	with	ADP
fnp-2971	157	49	amoeboid	amoeboid	ADJ
fnp-2971	157	50	phenotype	phenotype	NOUN
fnp-2971	157	51	(	(	PUNCT
fnp-2971	157	52	hla	hla	PROPN
fnp-2971	157	53	-	-	PUNCT
fnp-2971	157	54	dr	dr	PROPN
fnp-2971	157	55	;	;	PUNCT
fnp-2971	157	56	scale	scale	NOUN
fnp-2971	157	57	bar	bar	NOUN
fnp-2971	157	58	:	:	PUNCT
fnp-2971	157	59	500	500	NUM
fnp-2971	157	60	µm	µm	NUM
fnp-2971	157	61	)	)	PUNCT
fnp-2971	157	62	.	.	PUNCT
fnp-2971	158	1	(	(	PUNCT
fnp-2971	158	2	e	e	NOUN
fnp-2971	158	3	)	)	PUNCT
fnp-2971	158	4	higher	high	ADJ
fnp-2971	158	5	magnification	magnification	NOUN
fnp-2971	158	6	of	of	ADP
fnp-2971	158	7	the	the	DET
fnp-2971	158	8	better	well	ADV
fnp-2971	158	9	-	-	PUNCT
fnp-2971	158	10	preserved	preserve	VERB
fnp-2971	158	11	area	area	NOUN
fnp-2971	158	12	in	in	ADP
fnp-2971	158	13	(	(	PUNCT
fnp-2971	158	14	c	c	NOUN
fnp-2971	158	15	)	)	PUNCT
fnp-2971	158	16	.	.	PUNCT
fnp-2971	159	1	although	although	SCONJ
fnp-2971	159	2	there	there	PRON
fnp-2971	159	3	is	be	VERB
fnp-2971	159	4	a	a	DET
fnp-2971	159	5	marked	mark	VERB
fnp-2971	159	6	loss	loss	NOUN
fnp-2971	159	7	of	of	ADP
fnp-2971	159	8	myelinated	myelinated	ADJ
fnp-2971	159	9	fibers	fiber	NOUN
fnp-2971	159	10	,	,	PUNCT
fnp-2971	159	11	a	a	DET
fnp-2971	159	12	few	few	ADJ
fnp-2971	159	13	scattered	scatter	VERB
fnp-2971	159	14	myelinated	myelinated	ADJ
fnp-2971	159	15	fibers	fiber	NOUN
fnp-2971	159	16	remain	remain	VERB
fnp-2971	159	17	,	,	PUNCT
fnp-2971	159	18	neuropil	neuropil	PROPN
fnp-2971	159	19	appears	appear	VERB
fnp-2971	159	20	more	more	ADV
fnp-2971	159	21	compacted	compact	VERB
fnp-2971	159	22	,	,	PUNCT
fnp-2971	159	23	and	and	CCONJ
fnp-2971	159	24	the	the	DET
fnp-2971	159	25	loss	loss	NOUN
fnp-2971	159	26	of	of	ADP
fnp-2971	159	27	oligodendrocytes	oligodendrocyte	NOUN
fnp-2971	159	28	is	be	AUX
fnp-2971	159	29	mild	mild	ADJ
fnp-2971	159	30	to	to	AUX
fnp-2971	159	31	moderate	moderate	ADJ
fnp-2971	159	32	(	(	PUNCT
fnp-2971	159	33	lfb	lfb	PROPN
fnp-2971	159	34	-	-	PUNCT
fnp-2971	159	35	he	he	PRON
fnp-2971	159	36	;	;	PUNCT
fnp-2971	159	37	scale	scale	NOUN
fnp-2971	159	38	bar	bar	NOUN
fnp-2971	159	39	:	:	PUNCT
fnp-2971	159	40	50	50	NUM
fnp-2971	159	41	µm	µm	NOUN
fnp-2971	159	42	)	)	PUNCT
fnp-2971	159	43	.	.	PUNCT
fnp-2971	160	1	(	(	PUNCT
fnp-2971	160	2	f	f	X
fnp-2971	160	3	)	)	PUNCT
fnp-2971	160	4	higher	high	ADJ
fnp-2971	160	5	magnification	magnification	NOUN
fnp-2971	160	6	of	of	ADP
fnp-2971	160	7	the	the	DET
fnp-2971	160	8	central	central	ADJ
fnp-2971	160	9	area	area	NOUN
fnp-2971	160	10	in	in	ADP
fnp-2971	160	11	(	(	PUNCT
fnp-2971	160	12	d	d	NOUN
fnp-2971	160	13	)	)	PUNCT
fnp-2971	160	14	(	(	PUNCT
fnp-2971	160	15	hla	hla	PROPN
fnp-2971	160	16	-	-	PUNCT
fnp-2971	160	17	dr	dr	PROPN
fnp-2971	160	18	;	;	PUNCT
fnp-2971	160	19	scale	scale	NOUN
fnp-2971	160	20	bar	bar	NOUN
fnp-2971	160	21	:	:	PUNCT
fnp-2971	160	22	50	50	NUM
fnp-2971	160	23	µm	µm	NOUN
fnp-2971	160	24	)	)	PUNCT
fnp-2971	160	25	.	.	PUNCT
fnp-2971	161	1	(	(	PUNCT
fnp-2971	161	2	g	g	NOUN
fnp-2971	161	3	)	)	PUNCT
fnp-2971	161	4	the	the	DET
fnp-2971	161	5	rarefied	rarefy	VERB
fnp-2971	161	6	white	white	ADJ
fnp-2971	161	7	matter	matter	NOUN
fnp-2971	161	8	areas	area	NOUN
fnp-2971	161	9	show	show	VERB
fnp-2971	161	10	only	only	ADV
fnp-2971	161	11	occasional	occasional	ADJ
fnp-2971	161	12	myelinated	myelinated	ADJ
fnp-2971	161	13	fibers	fiber	NOUN
fnp-2971	161	14	,	,	PUNCT
fnp-2971	161	15	the	the	DET
fnp-2971	161	16	neuropil	neuropil	NOUN
fnp-2971	161	17	is	be	AUX
fnp-2971	161	18	rarefied	rarefy	VERB
fnp-2971	161	19	and	and	CCONJ
fnp-2971	161	20	mainly	mainly	ADV
fnp-2971	161	21	formed	form	VERB
fnp-2971	161	22	by	by	ADP
fnp-2971	161	23	astrocytic	astrocytic	ADJ
fnp-2971	161	24	processes	process	NOUN
fnp-2971	161	25	,	,	PUNCT
fnp-2971	161	26	and	and	CCONJ
fnp-2971	161	27	oligodendrocytes	oligodendrocyte	VERB
fnp-2971	161	28	loss	loss	NOUN
fnp-2971	161	29	is	be	AUX
fnp-2971	161	30	moderate	moderate	ADJ
fnp-2971	161	31	to	to	ADP
fnp-2971	161	32	severe	severe	ADJ
fnp-2971	161	33	(	(	PUNCT
fnp-2971	161	34	lfb	lfb	PROPN
fnp-2971	161	35	-	-	PUNCT
fnp-2971	161	36	he	he	PRON
fnp-2971	161	37	;	;	PUNCT
fnp-2971	161	38	scale	scale	NOUN
fnp-2971	161	39	bar	bar	NOUN
fnp-2971	161	40	:	:	PUNCT
fnp-2971	161	41	50	50	NUM
fnp-2971	161	42	µm	µm	NOUN
fnp-2971	161	43	)	)	PUNCT
fnp-2971	161	44	.	.	PUNCT
fnp-2971	162	1	(	(	PUNCT
fnp-2971	162	2	h	h	X
fnp-2971	162	3	)	)	PUNCT
fnp-2971	162	4	hla	hla	PROPN
fnp-2971	162	5	-	-	PUNCT
fnp-2971	162	6	dr	dr	PROPN
fnp-2971	162	7	immunostaining	immunostaining	NOUN
fnp-2971	162	8	of	of	ADP
fnp-2971	162	9	the	the	DET
fnp-2971	162	10	area	area	NOUN
fnp-2971	162	11	in	in	ADP
fnp-2971	162	12	(	(	PUNCT
fnp-2971	162	13	g	g	NOUN
fnp-2971	162	14	)	)	PUNCT
fnp-2971	162	15	shows	show	VERB
fnp-2971	162	16	mainly	mainly	ADV
fnp-2971	162	17	microglia	microglia	ADJ
fnp-2971	162	18	with	with	ADP
fnp-2971	162	19	the	the	DET
fnp-2971	162	20	amoeboid	amoeboid	ADJ
fnp-2971	162	21	phenotype	phenotype	NOUN
fnp-2971	162	22	(	(	PUNCT
fnp-2971	162	23	hla	hla	PROPN
fnp-2971	162	24	-	-	PUNCT
fnp-2971	162	25	dr	dr	PROPN
fnp-2971	162	26	;	;	PUNCT
fnp-2971	162	27	scale	scale	NOUN
fnp-2971	162	28	bar	bar	NOUN
fnp-2971	162	29	:	:	PUNCT
fnp-2971	162	30	100	100	NUM
fnp-2971	162	31	µm	µm	NOUN
fnp-2971	162	32	)	)	PUNCT
fnp-2971	162	33	.	.	PUNCT
fnp-2971	163	1	all	all	DET
fnp-2971	163	2	images	image	NOUN
fnp-2971	163	3	in	in	ADP
fnp-2971	163	4	this	this	DET
fnp-2971	163	5	figure	figure	NOUN
fnp-2971	163	6	are	be	AUX
fnp-2971	163	7	representative	representative	ADJ
fnp-2971	163	8	of	of	ADP
fnp-2971	163	9	case	case	NOUN
fnp-2971	163	10	6	6	NUM
fnp-2971	163	11	.	.	PUNCT
fnp-2971	163	12	morphological	morphological	ADJ
fnp-2971	163	13	correlation	correlation	NOUN
fnp-2971	163	14	of	of	ADP
fnp-2971	163	15	microglia	microglia	ADJ
fnp-2971	163	16	and	and	CCONJ
fnp-2971	163	17	axonal	axonal	ADJ
fnp-2971	163	18	degeneration	degeneration	NOUN
fnp-2971	163	19	tada	tada	PROPN
fnp-2971	163	20	et	et	PROPN
fnp-2971	163	21	al	al	PROPN
fnp-2971	163	22	.	.	PROPN
fnp-2971	163	23	described	describe	VERB
fnp-2971	163	24	“	"	PUNCT
fnp-2971	163	25	dysplastic	dysplastic	ADJ
fnp-2971	163	26	”	"	PUNCT
fnp-2971	163	27	microglia	microglia	NOUN
fnp-2971	163	28	in	in	ADP
fnp-2971	163	29	brain	brain	NOUN
fnp-2971	163	30	samples	sample	NOUN
fnp-2971	163	31	from	from	ADP
fnp-2971	163	32	six	six	NUM
fnp-2971	163	33	patients	patient	NOUN
fnp-2971	163	34	with	with	ADP
fnp-2971	163	35	confirmed	confirm	VERB
fnp-2971	163	36	csf1r	csf1r	PROPN
fnp-2971	163	37	mutations	mutation	NOUN
fnp-2971	163	38	(	(	PUNCT
fnp-2971	163	39	4	4	NUM
fnp-2971	163	40	)	)	PUNCT
fnp-2971	163	41	.	.	PUNCT
fnp-2971	164	1	these	these	DET
fnp-2971	164	2	dysplastic	dysplastic	ADJ
fnp-2971	164	3	microglia	microglia	NOUN
fnp-2971	164	4	were	be	AUX
fnp-2971	164	5	interpreted	interpret	VERB
fnp-2971	164	6	as	as	ADP
fnp-2971	164	7	the	the	DET
fnp-2971	164	8	morphological	morphological	ADJ
fnp-2971	164	9	manifestation	manifestation	NOUN
fnp-2971	164	10	of	of	ADP
fnp-2971	164	11	the	the	DET
fnp-2971	164	12	csf1r	csf1r	PROPN
fnp-2971	164	13	mutation	mutation	NOUN
fnp-2971	164	14	,	,	PUNCT
fnp-2971	164	15	but	but	CCONJ
fnp-2971	164	16	no	no	DET
fnp-2971	164	17	association	association	NOUN
fnp-2971	164	18	with	with	ADP
fnp-2971	164	19	axonal	axonal	ADJ
fnp-2971	164	20	spheroids	spheroid	NOUN
fnp-2971	164	21	was	be	AUX
fnp-2971	164	22	established	establish	VERB
fnp-2971	164	23	.	.	PUNCT
fnp-2971	165	1	in	in	ADP
fnp-2971	165	2	this	this	DET
fnp-2971	165	3	study	study	NOUN
fnp-2971	165	4	,	,	PUNCT
fnp-2971	165	5	we	we	PRON
fnp-2971	165	6	observed	observe	VERB
fnp-2971	165	7	various	various	ADJ
fnp-2971	165	8	reactive	reactive	ADJ
fnp-2971	165	9	microglia	microglia	NOUN
fnp-2971	165	10	morphologies	morphology	NOUN
fnp-2971	165	11	,	,	PUNCT
fnp-2971	165	12	including	include	VERB
fnp-2971	165	13	some	some	PRON
fnp-2971	165	14	that	that	PRON
fnp-2971	165	15	can	can	AUX
fnp-2971	165	16	be	be	AUX
fnp-2971	165	17	considered	consider	VERB
fnp-2971	165	18	“	"	PUNCT
fnp-2971	165	19	dystrophic”/“dysplastic	dystrophic”/“dysplastic	NOUN
fnp-2971	165	20	”	"	PUNCT
fnp-2971	165	21	.	.	PUNCT
fnp-2971	166	1	however	however	ADV
fnp-2971	166	2	,	,	PUNCT
fnp-2971	166	3	the	the	DET
fnp-2971	166	4	significance	significance	NOUN
fnp-2971	166	5	of	of	ADP
fnp-2971	166	6	these	these	DET
fnp-2971	166	7	changes	change	NOUN
fnp-2971	166	8	was	be	AUX
fnp-2971	166	9	hard	hard	ADJ
fnp-2971	166	10	to	to	PART
fnp-2971	166	11	interpret	interpret	VERB
fnp-2971	166	12	and	and	CCONJ
fnp-2971	166	13	to	to	PART
fnp-2971	166	14	correlate	correlate	VERB
fnp-2971	166	15	with	with	ADP
fnp-2971	166	16	the	the	DET
fnp-2971	166	17	pathology	pathology	NOUN
fnp-2971	166	18	.	.	PUNCT
fnp-2971	167	1	a	a	DET
fnp-2971	167	2	different	different	ADJ
fnp-2971	167	3	sequence	sequence	NOUN
fnp-2971	167	4	of	of	ADP
fnp-2971	167	5	events	event	NOUN
fnp-2971	167	6	in	in	ADP
fnp-2971	167	7	the	the	DET
fnp-2971	167	8	pathogenesis	pathogenesis	NOUN
fnp-2971	167	9	of	of	ADP
fnp-2971	167	10	alas	alas	PRON
fnp-2971	167	11	has	have	AUX
fnp-2971	167	12	been	be	AUX
fnp-2971	167	13	suggested	suggest	VERB
fnp-2971	167	14	.	.	PUNCT
fnp-2971	168	1	riku	riku	NOUN
fnp-2971	168	2	et	et	PROPN
fnp-2971	168	3	al	al	PROPN
fnp-2971	168	4	.	.	PROPN
fnp-2971	168	5	concluded	conclude	VERB
fnp-2971	168	6	that	that	SCONJ
fnp-2971	168	7	broad	broad	ADJ
fnp-2971	168	8	microglial	microglial	ADJ
fnp-2971	168	9	impairment	impairment	NOUN
fnp-2971	168	10	and	and	CCONJ
fnp-2971	168	11	low	low	ADJ
fnp-2971	168	12	csf1r	csf1r	NOUN
fnp-2971	168	13	expression	expression	NOUN
fnp-2971	168	14	on	on	ADP
fnp-2971	168	15	microglia	microglia	ADJ
fnp-2971	168	16	preceded	precede	VERB
fnp-2971	168	17	multifocal	multifocal	ADJ
fnp-2971	168	18	axonal	axonal	ADJ
fnp-2971	168	19	degeneration	degeneration	NOUN
fnp-2971	168	20	(	(	PUNCT
fnp-2971	168	21	6	6	NUM
fnp-2971	168	22	)	)	PUNCT
fnp-2971	168	23	.	.	PUNCT
fnp-2971	169	1	meanwhile	meanwhile	ADV
fnp-2971	169	2	,	,	PUNCT
fnp-2971	169	3	oyanagi	oyanagi	PROPN
fnp-2971	169	4	et	et	PROPN
fnp-2971	169	5	al	al	PROPN
fnp-2971	169	6	.	.	PROPN
fnp-2971	169	7	concluded	conclude	VERB
fnp-2971	169	8	that	that	SCONJ
fnp-2971	169	9	microglia	microglia	ADJ
fnp-2971	169	10	proliferation	proliferation	NOUN
fnp-2971	169	11	preceded	precede	VERB
fnp-2971	169	12	axonal	axonal	ADJ
fnp-2971	169	13	swelling	swelling	NOUN
fnp-2971	169	14	and	and	CCONJ
fnp-2971	169	15	loss	loss	NOUN
fnp-2971	169	16	.	.	PUNCT
fnp-2971	170	1	this	this	DET
fnp-2971	170	2	conclusion	conclusion	NOUN
fnp-2971	170	3	suggests	suggest	VERB
fnp-2971	170	4	that	that	SCONJ
fnp-2971	170	5	microglial	microglial	ADJ
fnp-2971	170	6	proliferation	proliferation	NOUN
fnp-2971	170	7	rather	rather	ADV
fnp-2971	170	8	than	than	ADP
fnp-2971	170	9	loss	loss	NOUN
fnp-2971	170	10	leads	lead	VERB
fnp-2971	170	11	to	to	ADP
fnp-2971	170	12	pathology	pathology	NOUN
fnp-2971	170	13	(	(	PUNCT
fnp-2971	170	14	i.e.	i.e.	X
fnp-2971	170	15	microglia	microglia	NOUN
fnp-2971	170	16	is	be	AUX
fnp-2971	170	17	harmful	harmful	ADJ
fnp-2971	170	18	and	and	CCONJ
fnp-2971	170	19	not	not	PART
fnp-2971	170	20	beneficial	beneficial	ADJ
fnp-2971	170	21	;	;	PUNCT
fnp-2971	170	22	7	7	X
fnp-2971	170	23	)	)	PUNCT
fnp-2971	170	24	,	,	PUNCT
fnp-2971	170	25	which	which	PRON
fnp-2971	170	26	stands	stand	VERB
fnp-2971	170	27	in	in	ADP
fnp-2971	170	28	contrast	contrast	NOUN
fnp-2971	170	29	to	to	ADP
fnp-2971	170	30	our	our	PRON
fnp-2971	170	31	conclusions	conclusion	NOUN
fnp-2971	170	32	.	.	PUNCT
fnp-2971	171	1	in	in	ADP
fnp-2971	171	2	this	this	DET
fnp-2971	171	3	study	study	NOUN
fnp-2971	171	4	,	,	PUNCT
fnp-2971	171	5	we	we	PRON
fnp-2971	171	6	concluded	conclude	VERB
fnp-2971	171	7	that	that	SCONJ
fnp-2971	171	8	microglial	microglial	ADJ
fnp-2971	171	9	loss	loss	NOUN
fnp-2971	171	10	preceded	precede	VERB
fnp-2971	171	11	axonal	axonal	ADJ
fnp-2971	171	12	degeneration	degeneration	NOUN
fnp-2971	171	13	based	base	VERB
fnp-2971	171	14	on	on	ADP
fnp-2971	171	15	the	the	DET
fnp-2971	171	16	following	follow	VERB
fnp-2971	171	17	observations	observation	NOUN
fnp-2971	171	18	:	:	PUNCT
fnp-2971	171	19	1	1	X
fnp-2971	171	20	)	)	PUNCT
fnp-2971	171	21	there	there	PRON
fnp-2971	171	22	is	be	VERB
fnp-2971	171	23	a	a	DET
fnp-2971	171	24	consistent	consistent	ADJ
fnp-2971	171	25	complete	complete	ADJ
fnp-2971	171	26	loss	loss	NOUN
fnp-2971	171	27	of	of	ADP
fnp-2971	171	28	ramified	ramified	ADJ
fnp-2971	171	29	microglia	microglia	NOUN
fnp-2971	171	30	(	(	PUNCT
fnp-2971	171	31	by	by	ADP
fnp-2971	171	32	both	both	PRON
fnp-2971	171	33	hla	hla	PROPN
fnp-2971	171	34	-	-	PUNCT
fnp-2971	171	35	dr	dr	PROPN
fnp-2971	171	36	&	&	CCONJ
fnp-2971	171	37	iba1	iba1	PROPN
fnp-2971	171	38	immunostains	immunostain	NOUN
fnp-2971	171	39	)	)	PUNCT
fnp-2971	171	40	in	in	ADP
fnp-2971	171	41	all	all	DET
fnp-2971	171	42	areas	area	NOUN
fnp-2971	171	43	with	with	ADP
fnp-2971	171	44	axonal	axonal	ADJ
fnp-2971	171	45	spheroids	spheroid	NOUN
fnp-2971	171	46	.	.	PUNCT
fnp-2971	172	1	as	as	SCONJ
fnp-2971	172	2	we	we	PRON
fnp-2971	172	3	did	do	AUX
fnp-2971	172	4	not	not	PART
fnp-2971	172	5	observe	observe	VERB
fnp-2971	172	6	any	any	DET
fnp-2971	172	7	area	area	NOUN
fnp-2971	172	8	with	with	ADP
fnp-2971	172	9	axonal	axonal	ADJ
fnp-2971	172	10	spheroids	spheroid	NOUN
fnp-2971	172	11	to	to	PART
fnp-2971	172	12	have	have	VERB
fnp-2971	172	13	reactive	reactive	ADJ
fnp-2971	172	14	ramified	ramify	VERB
fnp-2971	172	15	microglia	microglia	NOUN
fnp-2971	172	16	,	,	PUNCT
fnp-2971	172	17	it	it	PRON
fnp-2971	172	18	is	be	AUX
fnp-2971	172	19	unlikely	unlikely	ADJ
fnp-2971	172	20	that	that	SCONJ
fnp-2971	172	21	axonal	axonal	ADJ
fnp-2971	172	22	spheroids	spheroid	NOUN
fnp-2971	172	23	precede	precede	VERB
fnp-2971	172	24	microglia	microglia	ADJ
fnp-2971	172	25	loss	loss	NOUN
fnp-2971	172	26	.	.	PUNCT
fnp-2971	173	1	2	2	X
fnp-2971	173	2	)	)	PUNCT
fnp-2971	173	3	there	there	PRON
fnp-2971	173	4	is	be	VERB
fnp-2971	173	5	a	a	DET
fnp-2971	173	6	presence	presence	NOUN
fnp-2971	173	7	of	of	ADP
fnp-2971	173	8	“	"	PUNCT
fnp-2971	173	9	susceptible	susceptible	ADJ
fnp-2971	173	10	areas	area	NOUN
fnp-2971	173	11	”	"	PUNCT
fnp-2971	173	12	in	in	ADP
fnp-2971	173	13	stage	stage	NOUN
fnp-2971	173	14	2	2	NUM
fnp-2971	173	15	(	(	PUNCT
fnp-2971	173	16	i.e.	i.e.	X
fnp-2971	173	17	areas	area	NOUN
fnp-2971	173	18	with	with	ADP
fnp-2971	173	19	no	no	DET
fnp-2971	173	20	ramified	ramified	ADJ
fnp-2971	173	21	microglia	microglia	NOUN
fnp-2971	173	22	and	and	CCONJ
fnp-2971	173	23	no	no	DET
fnp-2971	173	24	axonal	axonal	ADJ
fnp-2971	173	25	spheroids	spheroid	NOUN
fnp-2971	173	26	)	)	PUNCT
fnp-2971	173	27	.	.	PUNCT
fnp-2971	174	1	ramified	ramify	VERB
fnp-2971	174	2	microglia	microglia	ADJ
fnp-2971	174	3	loss	loss	NOUN
fnp-2971	174	4	in	in	ADP
fnp-2971	174	5	these	these	DET
fnp-2971	174	6	areas	area	NOUN
fnp-2971	174	7	are	be	AUX
fnp-2971	174	8	significant	significant	ADJ
fnp-2971	174	9	as	as	SCONJ
fnp-2971	174	10	reactive	reactive	ADJ
fnp-2971	174	11	microglia	microglia	NOUN
fnp-2971	174	12	should	should	AUX
fnp-2971	174	13	be	be	AUX
fnp-2971	174	14	present	present	ADJ
fnp-2971	174	15	in	in	ADP
fnp-2971	174	16	areas	area	NOUN
fnp-2971	174	17	with	with	ADP
fnp-2971	174	18	white	white	ADJ
fnp-2971	174	19	matter	matter	NOUN
fnp-2971	174	20	pathology	pathology	NOUN
fnp-2971	174	21	.	.	PUNCT
fnp-2971	175	1	the	the	DET
fnp-2971	175	2	presence	presence	NOUN
fnp-2971	175	3	of	of	ADP
fnp-2971	175	4	microglia	microglia	NOUN
fnp-2971	175	5	with	with	ADP
fnp-2971	175	6	amoeboid	amoeboid	ADJ
fnp-2971	175	7	phenotypes	phenotype	NOUN
fnp-2971	175	8	in	in	ADP
fnp-2971	175	9	these	these	DET
fnp-2971	175	10	areas	area	NOUN
fnp-2971	175	11	confirm	confirm	VERB
fnp-2971	175	12	the	the	DET
fnp-2971	175	13	reliability	reliability	NOUN
fnp-2971	175	14	of	of	ADP
fnp-2971	175	15	microglia	microglia	NOUN
fnp-2971	175	16	immunostaining	immunostaine	VERB
fnp-2971	175	17	in	in	ADP
fnp-2971	175	18	these	these	DET
fnp-2971	175	19	sections	section	NOUN
fnp-2971	175	20	.	.	PUNCT
fnp-2971	176	1	3	3	X
fnp-2971	176	2	)	)	PUNCT
fnp-2971	176	3	there	there	PRON
fnp-2971	176	4	is	be	VERB
fnp-2971	176	5	a	a	DET
fnp-2971	176	6	presence	presence	NOUN
fnp-2971	176	7	of	of	ADP
fnp-2971	176	8	morphologically	morphologically	ADV
fnp-2971	176	9	abnormal	abnormal	ADJ
fnp-2971	176	10	microglia	microglia	NOUN
fnp-2971	176	11	in	in	ADP
fnp-2971	176	12	normal	normal	ADJ
fnp-2971	176	13	-	-	PUNCT
fnp-2971	176	14	appearing	appear	VERB
fnp-2971	176	15	white	white	ADJ
fnp-2971	176	16	matter	matter	NOUN
fnp-2971	176	17	.	.	PUNCT
fnp-2971	177	1	tada	tada	PROPN
fnp-2971	177	2	et	et	PROPN
fnp-2971	177	3	al	al	PROPN
fnp-2971	177	4	.	.	PROPN
fnp-2971	177	5	,	,	PUNCT
fnp-2971	177	6	using	use	VERB
fnp-2971	177	7	ultrastructural	ultrastructural	ADJ
fnp-2971	177	8	examination	examination	NOUN
fnp-2971	177	9	,	,	PUNCT
fnp-2971	177	10	considered	consider	VERB
fnp-2971	177	11	these	these	DET
fnp-2971	177	12	dysplastic	dysplastic	ADJ
fnp-2971	177	13	(	(	PUNCT
fnp-2971	177	14	4	4	NUM
fnp-2971	177	15	)	)	PUNCT
fnp-2971	177	16	.	.	PUNCT
fnp-2971	178	1	methodological	methodological	ADJ
fnp-2971	178	2	differences	difference	NOUN
fnp-2971	178	3	between	between	ADP
fnp-2971	178	4	the	the	DET
fnp-2971	178	5	studies	study	NOUN
fnp-2971	178	6	might	might	AUX
fnp-2971	178	7	explain	explain	VERB
fnp-2971	178	8	the	the	DET
fnp-2971	178	9	difference	difference	NOUN
fnp-2971	178	10	in	in	ADP
fnp-2971	178	11	conclusions	conclusion	NOUN
fnp-2971	178	12	between	between	ADP
fnp-2971	178	13	this	this	DET
fnp-2971	178	14	study	study	NOUN
fnp-2971	178	15	and	and	CCONJ
fnp-2971	178	16	previous	previous	ADJ
fnp-2971	178	17	studies	study	NOUN
fnp-2971	178	18	.	.	PUNCT
fnp-2971	179	1	in	in	ADP
fnp-2971	179	2	this	this	DET
fnp-2971	179	3	study	study	NOUN
fnp-2971	179	4	we	we	PRON
fnp-2971	179	5	described	describe	VERB
fnp-2971	179	6	the	the	DET
fnp-2971	179	7	correlation	correlation	NOUN
fnp-2971	179	8	between	between	ADP
fnp-2971	179	9	the	the	DET
fnp-2971	179	10	axonal	axonal	ADJ
fnp-2971	179	11	spheroids	spheroid	NOUN
fnp-2971	179	12	and	and	CCONJ
fnp-2971	179	13	ramified	ramify	VERB
fnp-2971	179	14	microglia	microglia	NOUN
fnp-2971	179	15	in	in	ADP
fnp-2971	179	16	each	each	DET
fnp-2971	179	17	lesion	lesion	NOUN
fnp-2971	179	18	based	base	VERB
fnp-2971	179	19	on	on	ADP
fnp-2971	179	20	its	its	PRON
fnp-2971	179	21	stage	stage	NOUN
fnp-2971	179	22	rather	rather	ADV
fnp-2971	179	23	than	than	ADP
fnp-2971	179	24	the	the	DET
fnp-2971	179	25	overall	overall	ADJ
fnp-2971	179	26	brain	brain	NOUN
fnp-2971	179	27	pathology	pathology	NOUN
fnp-2971	179	28	used	use	VERB
fnp-2971	179	29	by	by	ADP
fnp-2971	179	30	oyanagi	oyanagi	PROPN
fnp-2971	179	31	et	et	PROPN
fnp-2971	179	32	al	al	PROPN
fnp-2971	179	33	.	.	PUNCT
fnp-2971	180	1	the	the	DET
fnp-2971	180	2	latter	latter	ADJ
fnp-2971	180	3	system	system	NOUN
fnp-2971	180	4	is	be	AUX
fnp-2971	180	5	useful	useful	ADJ
fnp-2971	180	6	for	for	ADP
fnp-2971	180	7	the	the	DET
fnp-2971	180	8	correlation	correlation	NOUN
fnp-2971	180	9	of	of	ADP
fnp-2971	180	10	clinical	clinical	ADJ
fnp-2971	180	11	findings	finding	NOUN
fnp-2971	180	12	and	and	CCONJ
fnp-2971	180	13	the	the	DET
fnp-2971	180	14	duration	duration	NOUN
fnp-2971	180	15	of	of	ADP
fnp-2971	180	16	pathology	pathology	NOUN
fnp-2971	180	17	,	,	PUNCT
fnp-2971	180	18	while	while	SCONJ
fnp-2971	180	19	the	the	DET
fnp-2971	180	20	former	former	NOUN
fnp-2971	180	21	is	be	AUX
fnp-2971	180	22	more	more	ADV
fnp-2971	180	23	suitable	suitable	ADJ
fnp-2971	180	24	to	to	PART
fnp-2971	180	25	evaluate	evaluate	VERB
fnp-2971	180	26	the	the	DET
fnp-2971	180	27	mechanisms	mechanism	NOUN
fnp-2971	180	28	of	of	ADP
fnp-2971	180	29	a	a	DET
fnp-2971	180	30	multifocal	multifocal	ADJ
fnp-2971	180	31	disease	disease	NOUN
fnp-2971	180	32	showing	show	VERB
fnp-2971	180	33	lesions	lesion	NOUN
fnp-2971	180	34	with	with	ADP
fnp-2971	180	35	different	different	ADJ
fnp-2971	180	36	pathological	pathological	ADJ
fnp-2971	180	37	stages	stage	NOUN
fnp-2971	180	38	.	.	PUNCT
fnp-2971	181	1	similar	similar	ADJ
fnp-2971	181	2	limitations	limitation	NOUN
fnp-2971	181	3	may	may	AUX
fnp-2971	181	4	also	also	ADV
fnp-2971	181	5	apply	apply	VERB
fnp-2971	181	6	to	to	ADP
fnp-2971	181	7	the	the	DET
fnp-2971	181	8	conclusion	conclusion	NOUN
fnp-2971	181	9	drawn	draw	VERB
fnp-2971	181	10	by	by	ADP
fnp-2971	181	11	tada	tada	PROPN
fnp-2971	181	12	et	et	PROPN
fnp-2971	181	13	al	al	PROPN
fnp-2971	181	14	.	.	PROPN
fnp-2971	182	1	on	on	ADP
fnp-2971	182	2	the	the	DET
fnp-2971	182	3	microglial	microglial	ADJ
fnp-2971	182	4	distribution	distribution	NOUN
fnp-2971	182	5	in	in	ADP
fnp-2971	182	6	alas	alas	DET
fnp-2971	182	7	patients	patient	NOUN
fnp-2971	182	8	.	.	PUNCT
fnp-2971	183	1	they	they	PRON
fnp-2971	183	2	described	describe	VERB
fnp-2971	183	3	spatial	spatial	ADJ
fnp-2971	183	4	differences	difference	NOUN
fnp-2971	183	5	in	in	ADP
fnp-2971	183	6	microglia	microglia	ADJ
fnp-2971	183	7	distribution	distribution	NOUN
fnp-2971	183	8	with	with	ADP
fnp-2971	183	9	areas	area	NOUN
fnp-2971	183	10	showing	show	VERB
fnp-2971	183	11	reduced	reduce	VERB
fnp-2971	183	12	numbers	number	NOUN
fnp-2971	183	13	of	of	ADP
fnp-2971	183	14	microglia	microglia	NOUN
fnp-2971	183	15	and	and	CCONJ
fnp-2971	183	16	others	other	NOUN
fnp-2971	183	17	showing	show	VERB
fnp-2971	183	18	microgliosis	microgliosis	NOUN
fnp-2971	183	19	in	in	ADP
fnp-2971	183	20	both	both	CCONJ
fnp-2971	183	21	the	the	DET
fnp-2971	183	22	cortex	cortex	NOUN
fnp-2971	183	23	and	and	CCONJ
fnp-2971	183	24	the	the	DET
fnp-2971	183	25	white	white	ADJ
fnp-2971	183	26	matter	matter	NOUN
fnp-2971	183	27	.	.	PUNCT
fnp-2971	184	1	they	they	PRON
fnp-2971	184	2	concluded	conclude	VERB
fnp-2971	184	3	that	that	SCONJ
fnp-2971	184	4	this	this	DET
fnp-2971	184	5	differential	differential	ADJ
fnp-2971	184	6	distribution	distribution	NOUN
fnp-2971	184	7	interferes	interfere	VERB
fnp-2971	184	8	with	with	ADP
fnp-2971	184	9	any	any	DET
fnp-2971	184	10	meaningful	meaningful	ADJ
fnp-2971	184	11	quantitative	quantitative	ADJ
fnp-2971	184	12	statistical	statistical	ADJ
fnp-2971	184	13	study	study	NOUN
fnp-2971	184	14	of	of	ADP
fnp-2971	184	15	microglia	microglia	NOUN
fnp-2971	184	16	depending	depend	VERB
fnp-2971	184	17	on	on	ADP
fnp-2971	184	18	the	the	DET
fnp-2971	184	19	area	area	NOUN
fnp-2971	184	20	examined	examine	VERB
fnp-2971	184	21	(	(	PUNCT
fnp-2971	184	22	4	4	NUM
fnp-2971	184	23	)	)	PUNCT
fnp-2971	184	24	.	.	PUNCT
fnp-2971	185	1	this	this	DET
fnp-2971	185	2	conclusion	conclusion	NOUN
fnp-2971	185	3	is	be	AUX
fnp-2971	185	4	valid	valid	ADJ
fnp-2971	185	5	if	if	SCONJ
fnp-2971	185	6	all	all	DET
fnp-2971	185	7	lesions	lesion	NOUN
fnp-2971	185	8	are	be	AUX
fnp-2971	185	9	studied	study	VERB
fnp-2971	185	10	together	together	ADV
fnp-2971	185	11	as	as	ADP
fnp-2971	185	12	one	one	NUM
fnp-2971	185	13	stage	stage	NOUN
fnp-2971	185	14	but	but	CCONJ
fnp-2971	185	15	not	not	PART
fnp-2971	185	16	specifically	specifically	ADV
fnp-2971	185	17	for	for	ADP
fnp-2971	185	18	the	the	DET
fnp-2971	185	19	stage	stage	NOUN
fnp-2971	185	20	of	of	ADP
fnp-2971	185	21	the	the	DET
fnp-2971	185	22	individual	individual	ADJ
fnp-2971	185	23	lesion	lesion	NOUN
fnp-2971	185	24	as	as	SCONJ
fnp-2971	185	25	analyzed	analyze	VERB
fnp-2971	185	26	in	in	ADP
fnp-2971	185	27	this	this	DET
fnp-2971	185	28	study	study	NOUN
fnp-2971	185	29	.	.	PUNCT
fnp-2971	186	1	we	we	PRON
fnp-2971	186	2	found	find	VERB
fnp-2971	186	3	that	that	SCONJ
fnp-2971	186	4	this	this	DET
fnp-2971	186	5	spatial	spatial	ADJ
fnp-2971	186	6	distribution	distribution	NOUN
fnp-2971	186	7	did	do	AUX
fnp-2971	186	8	correlate	correlate	VERB
fnp-2971	186	9	with	with	ADP
fnp-2971	186	10	the	the	DET
fnp-2971	186	11	axonal	axonal	ADJ
fnp-2971	186	12	pathology	pathology	NOUN
fnp-2971	186	13	in	in	ADP
fnp-2971	186	14	alas	alas	PROPN
fnp-2971	186	15	.	.	PUNCT
fnp-2971	187	1	the	the	DET
fnp-2971	187	2	second	second	ADJ
fnp-2971	187	3	significant	significant	ADJ
fnp-2971	187	4	difference	difference	NOUN
fnp-2971	187	5	between	between	ADP
fnp-2971	187	6	the	the	DET
fnp-2971	187	7	previous	previous	ADJ
fnp-2971	187	8	studies	study	NOUN
fnp-2971	187	9	and	and	CCONJ
fnp-2971	187	10	our	our	PRON
fnp-2971	187	11	study	study	NOUN
fnp-2971	187	12	is	be	AUX
fnp-2971	187	13	that	that	SCONJ
fnp-2971	187	14	the	the	DET
fnp-2971	187	15	other	other	ADJ
fnp-2971	187	16	authors	author	NOUN
fnp-2971	187	17	did	do	AUX
fnp-2971	187	18	not	not	PART
fnp-2971	187	19	distinguish	distinguish	VERB
fnp-2971	187	20	between	between	ADP
fnp-2971	187	21	ramified	ramify	VERB
fnp-2971	187	22	microglia	microglia	NOUN
fnp-2971	187	23	and	and	CCONJ
fnp-2971	187	24	those	those	PRON
fnp-2971	187	25	with	with	ADP
fnp-2971	187	26	amoeboid	amoeboid	ADJ
fnp-2971	187	27	phenotype	phenotype	NOUN
fnp-2971	187	28	.	.	PUNCT
fnp-2971	188	1	many	many	ADJ
fnp-2971	188	2	morphological	morphological	ADJ
fnp-2971	188	3	variations	variation	NOUN
fnp-2971	188	4	of	of	ADP
fnp-2971	188	5	microglia	microglia	NOUN
fnp-2971	188	6	have	have	AUX
fnp-2971	188	7	been	be	AUX
fnp-2971	188	8	identified	identify	VERB
fnp-2971	188	9	(	(	PUNCT
fnp-2971	188	10	10	10	NUM
fnp-2971	188	11	)	)	PUNCT
fnp-2971	188	12	.	.	PUNCT
fnp-2971	189	1	although	although	SCONJ
fnp-2971	189	2	morphology	morphology	NOUN
fnp-2971	189	3	is	be	AUX
fnp-2971	189	4	not	not	PART
fnp-2971	189	5	a	a	DET
fnp-2971	189	6	reliable	reliable	ADJ
fnp-2971	189	7	predictor	predictor	NOUN
fnp-2971	189	8	of	of	ADP
fnp-2971	189	9	function	function	NOUN
fnp-2971	189	10	,	,	PUNCT
fnp-2971	189	11	microglia	microglia	ADJ
fnp-2971	189	12	with	with	ADP
fnp-2971	189	13	amoeboid	amoeboid	ADJ
fnp-2971	189	14	phenotype	phenotype	NOUN
fnp-2971	189	15	is	be	AUX
fnp-2971	189	16	an	an	DET
fnp-2971	189	17	exception	exception	NOUN
fnp-2971	189	18	as	as	SCONJ
fnp-2971	189	19	it	it	PRON
fnp-2971	189	20	is	be	AUX
fnp-2971	189	21	consistently	consistently	ADV
fnp-2971	189	22	associated	associate	VERB
fnp-2971	189	23	with	with	ADP
fnp-2971	189	24	phagocytosis	phagocytosis	NOUN
fnp-2971	189	25	(	(	PUNCT
fnp-2971	189	26	10	10	NUM
fnp-2971	189	27	)	)	PUNCT
fnp-2971	189	28	.	.	PUNCT
fnp-2971	190	1	therefore	therefore	ADV
fnp-2971	190	2	,	,	PUNCT
fnp-2971	190	3	we	we	PRON
fnp-2971	190	4	suggest	suggest	VERB
fnp-2971	190	5	that	that	SCONJ
fnp-2971	190	6	at	at	ADP
fnp-2971	190	7	least	least	ADJ
fnp-2971	190	8	the	the	DET
fnp-2971	190	9	microglia	microglia	NOUN
fnp-2971	190	10	with	with	ADP
fnp-2971	190	11	amoeboid	amoeboid	ADJ
fnp-2971	190	12	phenotype	phenotype	NOUN
fnp-2971	190	13	should	should	AUX
fnp-2971	190	14	be	be	AUX
fnp-2971	190	15	distinguished	distinguish	VERB
fnp-2971	190	16	from	from	ADP
fnp-2971	190	17	other	other	ADJ
fnp-2971	190	18	phenotypes	phenotype	NOUN
fnp-2971	190	19	.	.	PUNCT
fnp-2971	191	1	microglia	microglia	ADJ
fnp-2971	191	2	functions	function	NOUN
fnp-2971	191	3	and	and	CCONJ
fnp-2971	191	4	pathology	pathology	NOUN
fnp-2971	191	5	microglia	microglia	NOUN
fnp-2971	191	6	are	be	AUX
fnp-2971	191	7	regarded	regard	VERB
fnp-2971	191	8	as	as	ADP
fnp-2971	191	9	immune	immune	ADJ
fnp-2971	191	10	cells	cell	NOUN
fnp-2971	191	11	of	of	ADP
fnp-2971	191	12	the	the	DET
fnp-2971	191	13	central	central	ADJ
fnp-2971	191	14	nervous	nervous	ADJ
fnp-2971	191	15	system	system	NOUN
fnp-2971	191	16	(	(	PUNCT
fnp-2971	191	17	cns	cns	NOUN
fnp-2971	191	18	)	)	PUNCT
fnp-2971	191	19	and	and	CCONJ
fnp-2971	191	20	play	play	VERB
fnp-2971	191	21	a	a	DET
fnp-2971	191	22	role	role	NOUN
fnp-2971	191	23	in	in	ADP
fnp-2971	191	24	tackling	tackle	VERB
fnp-2971	191	25	viruses	virus	NOUN
fnp-2971	191	26	,	,	PUNCT
fnp-2971	191	27	phagocytosis	phagocytosis	NOUN
fnp-2971	191	28	,	,	PUNCT
fnp-2971	191	29	and	and	CCONJ
fnp-2971	191	30	as	as	ADP
fnp-2971	191	31	antigen	antigen	ADV
fnp-2971	191	32	-	-	PUNCT
fnp-2971	191	33	presenting	present	VERB
fnp-2971	191	34	cells	cell	NOUN
fnp-2971	191	35	(	(	PUNCT
fnp-2971	191	36	10	10	NUM
fnp-2971	191	37	,	,	PUNCT
fnp-2971	191	38	20	20	NUM
fnp-2971	191	39	)	)	PUNCT
fnp-2971	191	40	.	.	PUNCT
fnp-2971	192	1	recently	recently	ADV
fnp-2971	192	2	,	,	PUNCT
fnp-2971	192	3	additional	additional	ADJ
fnp-2971	192	4	functions	function	NOUN
fnp-2971	192	5	have	have	AUX
fnp-2971	192	6	been	be	AUX
fnp-2971	192	7	demonstrated	demonstrate	VERB
fnp-2971	192	8	,	,	PUNCT
fnp-2971	192	9	such	such	ADJ
fnp-2971	192	10	as	as	ADP
fnp-2971	192	11	active	active	ADJ
fnp-2971	192	12	surveillance	surveillance	NOUN
fnp-2971	192	13	of	of	ADP
fnp-2971	192	14	synaptic	synaptic	ADJ
fnp-2971	192	15	integrity	integrity	NOUN
fnp-2971	192	16	,	,	PUNCT
fnp-2971	192	17	regulation	regulation	NOUN
fnp-2971	192	18	of	of	ADP
fnp-2971	192	19	brain	brain	NOUN
fnp-2971	192	20	development	development	NOUN
fnp-2971	192	21	and	and	CCONJ
fnp-2971	192	22	potentially	potentially	ADV
fnp-2971	192	23	in	in	ADP
fnp-2971	192	24	blood	blood	NOUN
fnp-2971	192	25	vessel	vessel	NOUN
fnp-2971	192	26	formation	formation	NOUN
fnp-2971	192	27	(	(	PUNCT
fnp-2971	192	28	10	10	NUM
fnp-2971	192	29	,	,	PUNCT
fnp-2971	192	30	20	20	NUM
fnp-2971	192	31	)	)	PUNCT
fnp-2971	192	32	.	.	PUNCT
fnp-2971	193	1	microglia	microglia	NOUN
fnp-2971	193	2	have	have	AUX
fnp-2971	193	3	been	be	AUX
fnp-2971	193	4	considered	consider	VERB
fnp-2971	193	5	both	both	DET
fnp-2971	193	6	pro	pro	ADJ
fnp-2971	193	7	-	-	ADJ
fnp-2971	193	8	inflammatory	inflammatory	ADJ
fnp-2971	193	9	and	and	CCONJ
fnp-2971	193	10	anti	anti	ADJ
fnp-2971	193	11	-	-	ADJ
fnp-2971	193	12	inflammatory	inflammatory	ADJ
fnp-2971	193	13	as	as	ADV
fnp-2971	193	14	well	well	ADV
fnp-2971	193	15	as	as	ADP
fnp-2971	193	16	neurotoxic	neurotoxic	ADJ
fnp-2971	193	17	and	and	CCONJ
fnp-2971	193	18	neuroprotective	neuroprotective	ADJ
fnp-2971	193	19	depending	depend	VERB
fnp-2971	193	20	on	on	ADP
fnp-2971	193	21	their	their	PRON
fnp-2971	193	22	functional	functional	ADJ
fnp-2971	193	23	profiles	profile	NOUN
fnp-2971	193	24	(	(	PUNCT
fnp-2971	193	25	10	10	NUM
fnp-2971	193	26	,	,	PUNCT
fnp-2971	193	27	20	20	NUM
fnp-2971	193	28	)	)	PUNCT
fnp-2971	193	29	.	.	PUNCT
fnp-2971	194	1	the	the	DET
fnp-2971	194	2	beneficial	beneficial	ADJ
fnp-2971	194	3	effects	effect	NOUN
fnp-2971	194	4	of	of	ADP
fnp-2971	194	5	microglia	microglia	NOUN
fnp-2971	194	6	described	describe	VERB
fnp-2971	194	7	include	include	VERB
fnp-2971	194	8	limiting	limit	VERB
fnp-2971	194	9	the	the	DET
fnp-2971	194	10	effects	effect	NOUN
fnp-2971	194	11	of	of	ADP
fnp-2971	194	12	cerebral	cerebral	ADJ
fnp-2971	194	13	ischemia	ischemia	NOUN
fnp-2971	194	14	in	in	ADP
fnp-2971	194	15	animal	animal	NOUN
fnp-2971	194	16	models	model	NOUN
fnp-2971	194	17	since	since	SCONJ
fnp-2971	194	18	their	their	PRON
fnp-2971	194	19	absence	absence	NOUN
fnp-2971	194	20	through	through	ADP
fnp-2971	194	21	csf1r	csf1r	PROPN
fnp-2971	194	22	blockade	blockade	NOUN
fnp-2971	194	23	results	result	NOUN
fnp-2971	194	24	in	in	ADP
fnp-2971	194	25	increased	increase	VERB
fnp-2971	194	26	infarct	infarct	NOUN
fnp-2971	194	27	size	size	NOUN
fnp-2971	194	28	(	(	PUNCT
fnp-2971	194	29	21–23	21–23	NUM
fnp-2971	194	30	)	)	PUNCT
fnp-2971	194	31	,	,	PUNCT
fnp-2971	194	32	while	while	SCONJ
fnp-2971	194	33	microglial	microglial	ADJ
fnp-2971	194	34	repopulation	repopulation	NOUN
fnp-2971	194	35	reverses	reverse	VERB
fnp-2971	194	36	this	this	DET
fnp-2971	194	37	effect	effect	NOUN
fnp-2971	194	38	(	(	PUNCT
fnp-2971	194	39	23	23	NUM
fnp-2971	194	40	)	)	PUNCT
fnp-2971	194	41	.	.	PUNCT
fnp-2971	195	1	microglial	microglial	ADJ
fnp-2971	195	2	loss	loss	NOUN
fnp-2971	195	3	due	due	ADP
fnp-2971	195	4	to	to	ADP
fnp-2971	195	5	absence	absence	NOUN
fnp-2971	195	6	of	of	ADP
fnp-2971	195	7	csf1r	csf1r	PROPN
fnp-2971	195	8	affects	affect	VERB
fnp-2971	195	9	brain	brain	NOUN
fnp-2971	195	10	development	development	NOUN
fnp-2971	195	11	and	and	CCONJ
fnp-2971	195	12	results	result	NOUN
fnp-2971	195	13	in	in	ADP
fnp-2971	195	14	olfactory	olfactory	ADJ
fnp-2971	195	15	deficits	deficit	NOUN
fnp-2971	195	16	in	in	ADP
fnp-2971	195	17	mice	mouse	NOUN
fnp-2971	195	18	(	(	PUNCT
fnp-2971	195	19	24	24	NUM
fnp-2971	195	20	)	)	PUNCT
fnp-2971	195	21	.	.	PUNCT
fnp-2971	196	1	most	most	ADJ
fnp-2971	196	2	harmful	harmful	ADJ
fnp-2971	196	3	effects	effect	NOUN
fnp-2971	196	4	of	of	ADP
fnp-2971	196	5	microglia	microglia	NOUN
fnp-2971	196	6	are	be	AUX
fnp-2971	196	7	associated	associate	VERB
fnp-2971	196	8	with	with	ADP
fnp-2971	196	9	the	the	DET
fnp-2971	196	10	concept	concept	NOUN
fnp-2971	196	11	of	of	ADP
fnp-2971	196	12	neuroinflammation	neuroinflammation	NOUN
fnp-2971	196	13	,	,	PUNCT
fnp-2971	196	14	especially	especially	ADV
fnp-2971	196	15	in	in	ADP
fnp-2971	196	16	multiple	multiple	ADJ
fnp-2971	196	17	sclerosis	sclerosis	NOUN
fnp-2971	196	18	(	(	PUNCT
fnp-2971	196	19	25	25	NUM
fnp-2971	196	20	)	)	PUNCT
fnp-2971	196	21	,	,	PUNCT
fnp-2971	196	22	and	and	CCONJ
fnp-2971	196	23	after	after	ADP
fnp-2971	196	24	traumatic	traumatic	ADJ
fnp-2971	196	25	brain	brain	NOUN
fnp-2971	196	26	injury	injury	NOUN
fnp-2971	196	27	(	(	PUNCT
fnp-2971	196	28	26	26	NUM
fnp-2971	196	29	,	,	PUNCT
fnp-2971	196	30	27	27	NUM
fnp-2971	196	31	)	)	PUNCT
fnp-2971	196	32	.	.	PUNCT
fnp-2971	197	1	however	however	ADV
fnp-2971	197	2	,	,	PUNCT
fnp-2971	197	3	the	the	DET
fnp-2971	197	4	term	term	NOUN
fnp-2971	197	5	and	and	CCONJ
fnp-2971	197	6	the	the	DET
fnp-2971	197	7	concept	concept	NOUN
fnp-2971	197	8	of	of	ADP
fnp-2971	197	9	neuroinflammation	neuroinflammation	NOUN
fnp-2971	197	10	should	should	AUX
fnp-2971	197	11	be	be	AUX
fnp-2971	197	12	used	use	VERB
fnp-2971	197	13	with	with	ADP
fnp-2971	197	14	extreme	extreme	ADJ
fnp-2971	197	15	caution	caution	NOUN
fnp-2971	197	16	,	,	PUNCT
fnp-2971	197	17	as	as	SCONJ
fnp-2971	197	18	suggested	suggest	VERB
fnp-2971	197	19	by	by	ADP
fnp-2971	197	20	graeber	graeber	NOUN
fnp-2971	197	21	and	and	CCONJ
fnp-2971	197	22	streit	streit	PROPN
fnp-2971	197	23	(	(	PUNCT
fnp-2971	197	24	20	20	NUM
fnp-2971	197	25	)	)	PUNCT
fnp-2971	197	26	.	.	PUNCT
fnp-2971	198	1	microglia	microglia	ADJ
fnp-2971	198	2	and	and	CCONJ
fnp-2971	198	3	axonal	axonal	ADJ
fnp-2971	198	4	pathology	pathology	NOUN
fnp-2971	198	5	there	there	PRON
fnp-2971	198	6	are	be	VERB
fnp-2971	198	7	only	only	ADV
fnp-2971	198	8	few	few	ADJ
fnp-2971	198	9	studies	study	NOUN
fnp-2971	198	10	that	that	PRON
fnp-2971	198	11	deal	deal	VERB
fnp-2971	198	12	with	with	ADP
fnp-2971	198	13	the	the	DET
fnp-2971	198	14	association	association	NOUN
fnp-2971	198	15	between	between	ADP
fnp-2971	198	16	the	the	DET
fnp-2971	198	17	axonal	axonal	ADJ
fnp-2971	198	18	pathology	pathology	NOUN
fnp-2971	198	19	and	and	CCONJ
fnp-2971	198	20	microglial	microglial	ADJ
fnp-2971	198	21	reaction	reaction	NOUN
fnp-2971	198	22	.	.	PUNCT
fnp-2971	199	1	in	in	ADP
fnp-2971	199	2	the	the	DET
fnp-2971	199	3	experimental	experimental	ADJ
fnp-2971	199	4	micropig	micropig	PROPN
fnp-2971	199	5	model	model	NOUN
fnp-2971	199	6	for	for	ADP
fnp-2971	199	7	mild	mild	ADJ
fnp-2971	199	8	traumatic	traumatic	ADJ
fnp-2971	199	9	brain	brain	NOUN
fnp-2971	199	10	injury	injury	NOUN
fnp-2971	199	11	,	,	PUNCT
fnp-2971	199	12	lafrenaye	lafrenaye	VERB
fnp-2971	199	13	et	et	PROPN
fnp-2971	199	14	al	al	PROPN
fnp-2971	199	15	.	.	PROPN
fnp-2971	199	16	found	find	VERB
fnp-2971	199	17	that	that	SCONJ
fnp-2971	199	18	activated	activate	VERB
fnp-2971	199	19	microglia	microglia	NOUN
fnp-2971	199	20	contacted	contact	VERB
fnp-2971	199	21	the	the	DET
fnp-2971	199	22	proximal	proximal	ADJ
fnp-2971	199	23	segments	segment	NOUN
fnp-2971	199	24	of	of	ADP
fnp-2971	199	25	injured	injure	VERB
fnp-2971	199	26	axons	axon	NOUN
fnp-2971	199	27	(	(	PUNCT
fnp-2971	199	28	i.e.	i.e.	X
fnp-2971	199	29	axonal	axonal	ADJ
fnp-2971	199	30	spheroids	spheroid	NOUN
fnp-2971	199	31	)	)	PUNCT
fnp-2971	199	32	within	within	ADP
fnp-2971	199	33	6	6	NUM
fnp-2971	199	34	hours	hour	NOUN
fnp-2971	199	35	of	of	ADP
fnp-2971	199	36	the	the	DET
fnp-2971	199	37	induced	induced	ADJ
fnp-2971	199	38	injury	injury	NOUN
fnp-2971	199	39	(	(	PUNCT
fnp-2971	199	40	28	28	NUM
fnp-2971	199	41	)	)	PUNCT
fnp-2971	199	42	.	.	PUNCT
fnp-2971	200	1	lafrenaye	lafrenaye	VERB
fnp-2971	200	2	et	et	PROPN
fnp-2971	200	3	al	al	PROPN
fnp-2971	200	4	.	.	PROPN
fnp-2971	200	5	suggested	suggest	VERB
fnp-2971	200	6	that	that	SCONJ
fnp-2971	200	7	microglia	microglia	ADJ
fnp-2971	200	8	activation	activation	NOUN
fnp-2971	200	9	is	be	AUX
fnp-2971	200	10	beneficial	beneficial	ADJ
fnp-2971	200	11	and	and	CCONJ
fnp-2971	200	12	may	may	AUX
fnp-2971	200	13	enhance	enhance	VERB
fnp-2971	200	14	axonal	axonal	ADJ
fnp-2971	200	15	regeneration	regeneration	NOUN
fnp-2971	200	16	through	through	ADP
fnp-2971	200	17	this	this	DET
fnp-2971	200	18	contact	contact	NOUN
fnp-2971	200	19	(	(	PUNCT
fnp-2971	200	20	29	29	NUM
fnp-2971	200	21	)	)	PUNCT
fnp-2971	200	22	.	.	PUNCT
fnp-2971	201	1	in	in	ADP
fnp-2971	201	2	a	a	DET
fnp-2971	201	3	human	human	ADJ
fnp-2971	201	4	study	study	NOUN
fnp-2971	201	5	,	,	PUNCT
fnp-2971	201	6	microglia	microglia	ADJ
fnp-2971	201	7	activation	activation	NOUN
fnp-2971	201	8	and	and	CCONJ
fnp-2971	201	9	microglia	microglia	ADJ
fnp-2971	201	10	nodules	nodule	NOUN
fnp-2971	201	11	were	be	AUX
fnp-2971	201	12	associated	associate	VERB
fnp-2971	201	13	with	with	ADP
fnp-2971	201	14	axonal	axonal	ADJ
fnp-2971	201	15	swelling	swelling	NOUN
fnp-2971	201	16	in	in	ADP
fnp-2971	201	17	the	the	DET
fnp-2971	201	18	perilesional	perilesional	ADJ
fnp-2971	201	19	white	white	ADJ
fnp-2971	201	20	matter	matter	NOUN
fnp-2971	201	21	.	.	PUNCT
fnp-2971	202	1	these	these	DET
fnp-2971	202	2	changes	change	NOUN
fnp-2971	202	3	were	be	AUX
fnp-2971	202	4	demonstrated	demonstrate	VERB
fnp-2971	202	5	in	in	ADP
fnp-2971	202	6	the	the	DET
fnp-2971	202	7	periplaque	periplaque	ADJ
fnp-2971	202	8	white	white	ADJ
fnp-2971	202	9	matter	matter	NOUN
fnp-2971	202	10	lesions	lesion	NOUN
fnp-2971	202	11	in	in	ADP
fnp-2971	202	12	multiple	multiple	ADJ
fnp-2971	202	13	sclerosis	sclerosis	NOUN
fnp-2971	202	14	,	,	PUNCT
fnp-2971	202	15	in	in	ADP
fnp-2971	202	16	white	white	ADJ
fnp-2971	202	17	matter	matter	NOUN
fnp-2971	202	18	areas	area	NOUN
fnp-2971	202	19	adjacent	adjacent	ADJ
fnp-2971	202	20	to	to	ADP
fnp-2971	202	21	infarcts	infarct	NOUN
fnp-2971	202	22	,	,	PUNCT
fnp-2971	202	23	and	and	CCONJ
fnp-2971	202	24	in	in	ADP
fnp-2971	202	25	traumatic	traumatic	ADJ
fnp-2971	202	26	brain	brain	NOUN
fnp-2971	202	27	injury	injury	NOUN
fnp-2971	202	28	(	(	PUNCT
fnp-2971	202	29	30	30	NUM
fnp-2971	202	30	)	)	PUNCT
fnp-2971	202	31	.	.	PUNCT
fnp-2971	203	1	in	in	ADP
fnp-2971	203	2	this	this	DET
fnp-2971	203	3	study	study	NOUN
fnp-2971	203	4	,	,	PUNCT
fnp-2971	203	5	the	the	DET
fnp-2971	203	6	preferred	preferred	ADJ
fnp-2971	203	7	hypothesis	hypothesis	NOUN
fnp-2971	203	8	was	be	AUX
fnp-2971	203	9	that	that	PRON
fnp-2971	203	10	microglial	microglial	ADJ
fnp-2971	203	11	reaction	reaction	NOUN
fnp-2971	203	12	/	/	SYM
fnp-2971	203	13	nodules	nodule	NOUN
fnp-2971	203	14	resulted	result	VERB
fnp-2971	203	15	in	in	ADP
fnp-2971	203	16	the	the	DET
fnp-2971	203	17	axonal	axonal	ADJ
fnp-2971	203	18	damage	damage	NOUN
fnp-2971	203	19	(	(	PUNCT
fnp-2971	203	20	30	30	NUM
fnp-2971	203	21	)	)	PUNCT
fnp-2971	203	22	.	.	PUNCT
fnp-2971	204	1	however	however	ADV
fnp-2971	204	2	,	,	PUNCT
fnp-2971	204	3	no	no	DET
fnp-2971	204	4	evidence	evidence	NOUN
fnp-2971	204	5	of	of	ADP
fnp-2971	204	6	the	the	DET
fnp-2971	204	7	timing	timing	NOUN
fnp-2971	204	8	of	of	ADP
fnp-2971	204	9	the	the	DET
fnp-2971	204	10	events	event	NOUN
fnp-2971	204	11	was	be	AUX
fnp-2971	204	12	provided	provide	VERB
fnp-2971	204	13	to	to	PART
fnp-2971	204	14	support	support	VERB
fnp-2971	204	15	this	this	DET
fnp-2971	204	16	conclusion	conclusion	NOUN
fnp-2971	204	17	.	.	PUNCT
fnp-2971	205	1	both	both	DET
fnp-2971	205	2	studies	study	NOUN
fnp-2971	205	3	(	(	PUNCT
fnp-2971	205	4	29	29	NUM
fnp-2971	205	5	,	,	PUNCT
fnp-2971	205	6	30	30	NUM
fnp-2971	205	7	)	)	PUNCT
fnp-2971	205	8	showed	show	VERB
fnp-2971	205	9	the	the	DET
fnp-2971	205	10	close	close	ADJ
fnp-2971	205	11	association	association	NOUN
fnp-2971	205	12	of	of	ADP
fnp-2971	205	13	reactive	reactive	ADJ
fnp-2971	205	14	microglia	microglia	NOUN
fnp-2971	205	15	to	to	ADP
fnp-2971	205	16	the	the	DET
fnp-2971	205	17	axonal	axonal	ADJ
fnp-2971	205	18	spheroids	spheroid	NOUN
fnp-2971	205	19	in	in	ADP
fnp-2971	205	20	affected	affect	VERB
fnp-2971	205	21	white	white	ADJ
fnp-2971	205	22	matter	matter	NOUN
fnp-2971	205	23	areas	area	NOUN
fnp-2971	205	24	.	.	PUNCT
fnp-2971	206	1	the	the	DET
fnp-2971	206	2	interpretation	interpretation	NOUN
fnp-2971	206	3	is	be	AUX
fnp-2971	206	4	quite	quite	ADV
fnp-2971	206	5	different	different	ADJ
fnp-2971	206	6	as	as	SCONJ
fnp-2971	206	7	the	the	DET
fnp-2971	206	8	latter	latter	ADJ
fnp-2971	206	9	study	study	NOUN
fnp-2971	206	10	suggested	suggest	VERB
fnp-2971	206	11	that	that	SCONJ
fnp-2971	206	12	neuroinflammation	neuroinflammation	NOUN
fnp-2971	206	13	(	(	PUNCT
fnp-2971	206	14	defined	define	VERB
fnp-2971	206	15	as	as	ADP
fnp-2971	206	16	a	a	DET
fnp-2971	206	17	microglial	microglial	ADJ
fnp-2971	206	18	reaction	reaction	NOUN
fnp-2971	206	19	)	)	PUNCT
fnp-2971	206	20	resulted	result	VERB
fnp-2971	206	21	in	in	ADP
fnp-2971	206	22	the	the	DET
fnp-2971	206	23	axonal	axonal	ADJ
fnp-2971	206	24	pathology	pathology	NOUN
fnp-2971	206	25	(	(	PUNCT
fnp-2971	206	26	30	30	NUM
fnp-2971	206	27	)	)	PUNCT
fnp-2971	206	28	,	,	PUNCT
fnp-2971	206	29	while	while	SCONJ
fnp-2971	206	30	the	the	DET
fnp-2971	206	31	former	former	ADJ
fnp-2971	206	32	study	study	NOUN
fnp-2971	206	33	found	find	VERB
fnp-2971	206	34	that	that	SCONJ
fnp-2971	206	35	microglia	microglia	ADJ
fnp-2971	206	36	reaction	reaction	NOUN
fnp-2971	206	37	is	be	AUX
fnp-2971	206	38	secondary	secondary	ADJ
fnp-2971	206	39	to	to	ADP
fnp-2971	206	40	axonal	axonal	ADJ
fnp-2971	206	41	injury	injury	NOUN
fnp-2971	206	42	and	and	CCONJ
fnp-2971	206	43	suggested	suggest	VERB
fnp-2971	206	44	a	a	DET
fnp-2971	206	45	neuroprotective	neuroprotective	ADJ
fnp-2971	206	46	function	function	NOUN
fnp-2971	206	47	to	to	ADP
fnp-2971	206	48	these	these	DET
fnp-2971	206	49	activated	activate	VERB
fnp-2971	206	50	microglia	microglia	NOUN
fnp-2971	206	51	.	.	PUNCT
fnp-2971	207	1	our	our	PRON
fnp-2971	207	2	study	study	NOUN
fnp-2971	207	3	described	describe	VERB
fnp-2971	207	4	a	a	DET
fnp-2971	207	5	different	different	ADJ
fnp-2971	207	6	association	association	NOUN
fnp-2971	207	7	between	between	ADP
fnp-2971	207	8	the	the	DET
fnp-2971	207	9	axonal	axonal	ADJ
fnp-2971	207	10	pathology	pathology	NOUN
fnp-2971	207	11	and	and	CCONJ
fnp-2971	207	12	the	the	DET
fnp-2971	207	13	ramified	ramified	ADJ
fnp-2971	207	14	microglia	microglia	NOUN
fnp-2971	207	15	,	,	PUNCT
fnp-2971	207	16	which	which	PRON
fnp-2971	207	17	,	,	PUNCT
fnp-2971	207	18	to	to	ADP
fnp-2971	207	19	our	our	PRON
fnp-2971	207	20	knowledge	knowledge	NOUN
fnp-2971	207	21	,	,	PUNCT
fnp-2971	207	22	has	have	AUX
fnp-2971	207	23	not	not	PART
fnp-2971	207	24	been	be	AUX
fnp-2971	207	25	described	describe	VERB
fnp-2971	207	26	before	before	ADV
fnp-2971	207	27	,	,	PUNCT
fnp-2971	207	28	and	and	CCONJ
fnp-2971	207	29	in	in	ADP
fnp-2971	207	30	which	which	PRON
fnp-2971	207	31	axonal	axonal	ADJ
fnp-2971	207	32	spheroids	spheroid	NOUN
fnp-2971	207	33	were	be	AUX
fnp-2971	207	34	associated	associate	VERB
fnp-2971	207	35	with	with	ADP
fnp-2971	207	36	loss	loss	NOUN
fnp-2971	207	37	of	of	ADP
fnp-2971	207	38	ramified	ramified	ADJ
fnp-2971	207	39	microglia	microglia	NOUN
fnp-2971	207	40	.	.	PUNCT
fnp-2971	208	1	the	the	DET
fnp-2971	208	2	remarkable	remarkable	ADJ
fnp-2971	208	3	restriction	restriction	NOUN
fnp-2971	208	4	of	of	ADP
fnp-2971	208	5	axonal	axonal	ADJ
fnp-2971	208	6	spheroids	spheroid	NOUN
fnp-2971	208	7	to	to	ADP
fnp-2971	208	8	these	these	DET
fnp-2971	208	9	areas	area	NOUN
fnp-2971	208	10	,	,	PUNCT
fnp-2971	208	11	best	well	ADV
fnp-2971	208	12	appreciated	appreciate	VERB
fnp-2971	208	13	in	in	ADP
fnp-2971	208	14	the	the	DET
fnp-2971	208	15	small	small	ADJ
fnp-2971	208	16	early	early	ADJ
fnp-2971	208	17	lesions	lesion	NOUN
fnp-2971	208	18	(	(	PUNCT
fnp-2971	208	19	i.e.	i.e.	X
fnp-2971	208	20	stage	stage	NOUN
fnp-2971	208	21	1	1	NUM
fnp-2971	208	22	pathology	pathology	NOUN
fnp-2971	208	23	)	)	PUNCT
fnp-2971	208	24	,	,	PUNCT
fnp-2971	208	25	suggests	suggest	VERB
fnp-2971	208	26	that	that	SCONJ
fnp-2971	208	27	the	the	DET
fnp-2971	208	28	loss	loss	NOUN
fnp-2971	208	29	of	of	ADP
fnp-2971	208	30	microglia	microglia	NOUN
fnp-2971	208	31	is	be	AUX
fnp-2971	208	32	protective	protective	ADJ
fnp-2971	208	33	in	in	ADP
fnp-2971	208	34	preventing	prevent	VERB
fnp-2971	208	35	this	this	DET
fnp-2971	208	36	pathology	pathology	NOUN
fnp-2971	208	37	.	.	PUNCT
fnp-2971	209	1	pathogenesis	pathogenesis	NOUN
fnp-2971	209	2	of	of	ADP
fnp-2971	209	3	alas	alas	PRON
fnp-2971	209	4	the	the	DET
fnp-2971	209	5	focus	focus	NOUN
fnp-2971	209	6	on	on	ADP
fnp-2971	209	7	the	the	DET
fnp-2971	209	8	pathogenesis	pathogenesis	NOUN
fnp-2971	209	9	of	of	ADP
fnp-2971	209	10	alas	alas	PRON
fnp-2971	209	11	has	have	AUX
fnp-2971	209	12	changed	change	VERB
fnp-2971	209	13	in	in	ADP
fnp-2971	209	14	the	the	DET
fnp-2971	209	15	literature	literature	NOUN
fnp-2971	209	16	since	since	SCONJ
fnp-2971	209	17	the	the	DET
fnp-2971	209	18	recognition	recognition	NOUN
fnp-2971	209	19	of	of	ADP
fnp-2971	209	20	csf1r	csf1r	PROPN
fnp-2971	209	21	mutations	mutation	NOUN
fnp-2971	209	22	in	in	ADP
fnp-2971	209	23	alas	alas	INTJ
fnp-2971	209	24	.	.	PUNCT
fnp-2971	210	1	previous	previous	ADJ
fnp-2971	210	2	pathological	pathological	ADJ
fnp-2971	210	3	studies	study	NOUN
fnp-2971	210	4	focused	focus	VERB
fnp-2971	210	5	on	on	ADP
fnp-2971	210	6	the	the	DET
fnp-2971	210	7	role	role	NOUN
fnp-2971	210	8	of	of	ADP
fnp-2971	210	9	axonal	axonal	ADJ
fnp-2971	210	10	pathology	pathology	NOUN
fnp-2971	210	11	in	in	ADP
fnp-2971	210	12	the	the	DET
fnp-2971	210	13	pathogenesis	pathogenesis	NOUN
fnp-2971	210	14	.	.	PUNCT
fnp-2971	211	1	the	the	DET
fnp-2971	211	2	most	most	ADV
fnp-2971	211	3	relevant	relevant	ADJ
fnp-2971	211	4	conclusions	conclusion	NOUN
fnp-2971	211	5	were	be	AUX
fnp-2971	211	6	:	:	PUNCT
fnp-2971	211	7	1	1	X
fnp-2971	211	8	)	)	PUNCT
fnp-2971	211	9	the	the	DET
fnp-2971	211	10	pathological	pathological	ADJ
fnp-2971	211	11	features	feature	NOUN
fnp-2971	211	12	of	of	ADP
fnp-2971	211	13	the	the	DET
fnp-2971	211	14	affected	affect	VERB
fnp-2971	211	15	white	white	ADJ
fnp-2971	211	16	matter	matter	NOUN
fnp-2971	211	17	suggest	suggest	VERB
fnp-2971	211	18	that	that	SCONJ
fnp-2971	211	19	the	the	DET
fnp-2971	211	20	main	main	ADJ
fnp-2971	211	21	pathological	pathological	ADJ
fnp-2971	211	22	process	process	NOUN
fnp-2971	211	23	is	be	AUX
fnp-2971	211	24	axonal	axonal	ADJ
fnp-2971	211	25	degeneration	degeneration	NOUN
fnp-2971	211	26	with	with	ADP
fnp-2971	211	27	secondary	secondary	ADJ
fnp-2971	211	28	demyelination	demyelination	NOUN
fnp-2971	211	29	(	(	PUNCT
fnp-2971	211	30	1	1	NUM
fnp-2971	211	31	)	)	PUNCT
fnp-2971	211	32	;	;	PUNCT
fnp-2971	211	33	2	2	X
fnp-2971	211	34	)	)	PUNCT
fnp-2971	211	35	the	the	DET
fnp-2971	211	36	recurring	recurring	NOUN
fnp-2971	211	37	or	or	CCONJ
fnp-2971	211	38	ongoing	ongoing	ADJ
fnp-2971	211	39	nature	nature	NOUN
fnp-2971	211	40	of	of	ADP
fnp-2971	211	41	the	the	DET
fnp-2971	211	42	pathology	pathology	NOUN
fnp-2971	211	43	is	be	AUX
fnp-2971	211	44	supported	support	VERB
fnp-2971	211	45	by	by	ADP
fnp-2971	211	46	the	the	DET
fnp-2971	211	47	gradual	gradual	ADJ
fnp-2971	211	48	progression	progression	NOUN
fnp-2971	211	49	of	of	ADP
fnp-2971	211	50	the	the	DET
fnp-2971	211	51	white	white	ADJ
fnp-2971	211	52	matter	matter	NOUN
fnp-2971	211	53	pathologic	pathologic	ADJ
fnp-2971	211	54	processes	process	NOUN
fnp-2971	211	55	(	(	PUNCT
fnp-2971	211	56	31	31	NUM
fnp-2971	211	57	,	,	PUNCT
fnp-2971	211	58	32	32	NUM
fnp-2971	211	59	)	)	PUNCT
fnp-2971	211	60	;	;	PUNCT
fnp-2971	211	61	and	and	CCONJ
fnp-2971	211	62	3	3	X
fnp-2971	211	63	)	)	PUNCT
fnp-2971	211	64	a	a	DET
fnp-2971	211	65	possible	possible	ADJ
fnp-2971	211	66	role	role	NOUN
fnp-2971	211	67	of	of	ADP
fnp-2971	211	68	hypoxic	hypoxic	ADJ
fnp-2971	211	69	-	-	PUNCT
fnp-2971	211	70	ischemic	ischemic	ADJ
fnp-2971	211	71	injuries	injury	NOUN
fnp-2971	211	72	in	in	ADP
fnp-2971	211	73	the	the	DET
fnp-2971	211	74	pathogenesis	pathogenesis	NOUN
fnp-2971	211	75	of	of	ADP
fnp-2971	211	76	alas	alas	PROPN
fnp-2971	211	77	(	(	PUNCT
fnp-2971	211	78	32	32	NUM
fnp-2971	211	79	,	,	PUNCT
fnp-2971	211	80	33	33	NUM
fnp-2971	211	81	)	)	PUNCT
fnp-2971	211	82	.	.	PUNCT
fnp-2971	212	1	studies	study	NOUN
fnp-2971	212	2	after	after	SCONJ
fnp-2971	212	3	the	the	DET
fnp-2971	212	4	discovery	discovery	NOUN
fnp-2971	212	5	of	of	ADP
fnp-2971	212	6	csf1r	csf1r	PROPN
fnp-2971	212	7	mutations	mutation	NOUN
fnp-2971	212	8	in	in	ADP
fnp-2971	212	9	alas	alas	PRON
fnp-2971	212	10	focused	focus	VERB
fnp-2971	212	11	on	on	ADP
fnp-2971	212	12	the	the	DET
fnp-2971	212	13	effect	effect	NOUN
fnp-2971	212	14	of	of	ADP
fnp-2971	212	15	these	these	DET
fnp-2971	212	16	mutations	mutation	NOUN
fnp-2971	212	17	on	on	ADP
fnp-2971	212	18	microglia	microglia	NOUN
fnp-2971	212	19	and	and	CCONJ
fnp-2971	212	20	the	the	DET
fnp-2971	212	21	morphological	morphological	ADJ
fnp-2971	212	22	changes	change	NOUN
fnp-2971	212	23	of	of	ADP
fnp-2971	212	24	microglia	microglia	NOUN
fnp-2971	212	25	in	in	ADP
fnp-2971	212	26	alas	alas	INTJ
fnp-2971	212	27	.	.	PUNCT
fnp-2971	213	1	the	the	DET
fnp-2971	213	2	most	most	ADV
fnp-2971	213	3	relevant	relevant	ADJ
fnp-2971	213	4	conclusions	conclusion	NOUN
fnp-2971	213	5	from	from	ADP
fnp-2971	213	6	these	these	DET
fnp-2971	213	7	studies	study	NOUN
fnp-2971	213	8	include	include	VERB
fnp-2971	213	9	:	:	PUNCT
fnp-2971	213	10	1	1	X
fnp-2971	213	11	)	)	PUNCT
fnp-2971	213	12	csf1r	csf1r	PROPN
fnp-2971	213	13	mutations	mutation	NOUN
fnp-2971	213	14	can	can	AUX
fnp-2971	213	15	affect	affect	VERB
fnp-2971	213	16	microglia	microglia	NOUN
fnp-2971	213	17	through	through	ADP
fnp-2971	213	18	loss	loss	NOUN
fnp-2971	213	19	of	of	ADP
fnp-2971	213	20	function	function	NOUN
fnp-2971	213	21	(	(	PUNCT
fnp-2971	213	22	haploinsufficiency	haploinsufficiency	PROPN
fnp-2971	213	23	model	model	NOUN
fnp-2971	213	24	;	;	PUNCT
fnp-2971	213	25	17	17	NUM
fnp-2971	213	26	)	)	PUNCT
fnp-2971	213	27	or	or	CCONJ
fnp-2971	213	28	dominant	dominant	ADJ
fnp-2971	213	29	-	-	PUNCT
fnp-2971	213	30	negative	negative	ADJ
fnp-2971	213	31	effect	effect	NOUN
fnp-2971	213	32	(	(	PUNCT
fnp-2971	213	33	18	18	NUM
fnp-2971	213	34	)	)	PUNCT
fnp-2971	213	35	;	;	PUNCT
fnp-2971	213	36	2	2	X
fnp-2971	213	37	)	)	PUNCT
fnp-2971	213	38	demonstration	demonstration	NOUN
fnp-2971	213	39	of	of	ADP
fnp-2971	213	40	dystrophic	dystrophic	ADJ
fnp-2971	213	41	microglia	microglia	NOUN
fnp-2971	213	42	as	as	ADP
fnp-2971	213	43	the	the	DET
fnp-2971	213	44	possible	possible	ADJ
fnp-2971	213	45	pathological	pathological	ADJ
fnp-2971	213	46	correlate	correlate	NOUN
fnp-2971	213	47	of	of	ADP
fnp-2971	213	48	these	these	DET
fnp-2971	213	49	mutations	mutation	NOUN
fnp-2971	213	50	(	(	PUNCT
fnp-2971	213	51	4	4	NUM
fnp-2971	213	52	)	)	PUNCT
fnp-2971	213	53	;	;	PUNCT
fnp-2971	213	54	3	3	X
fnp-2971	213	55	)	)	PUNCT
fnp-2971	213	56	change	change	NOUN
fnp-2971	213	57	of	of	ADP
fnp-2971	213	58	microglia	microglia	ADJ
fnp-2971	213	59	density	density	NOUN
fnp-2971	213	60	precedes	precede	VERB
fnp-2971	213	61	the	the	DET
fnp-2971	213	62	white	white	ADJ
fnp-2971	213	63	matter	matter	NOUN
fnp-2971	213	64	pathology	pathology	NOUN
fnp-2971	213	65	,	,	PUNCT
fnp-2971	213	66	but	but	CCONJ
fnp-2971	213	67	with	with	ADP
fnp-2971	213	68	contradicting	contradict	VERB
fnp-2971	213	69	results	result	NOUN
fnp-2971	213	70	.	.	PUNCT
fnp-2971	214	1	oyanagi	oyanagi	NOUN
fnp-2971	214	2	et	et	PROPN
fnp-2971	214	3	al	al	PROPN
fnp-2971	214	4	.	.	PROPN
fnp-2971	214	5	proposed	propose	VERB
fnp-2971	214	6	that	that	SCONJ
fnp-2971	214	7	microglia	microglia	ADJ
fnp-2971	214	8	proliferation	proliferation	NOUN
fnp-2971	214	9	preceded	precede	VERB
fnp-2971	214	10	axonal	axonal	ADJ
fnp-2971	214	11	degeneration	degeneration	NOUN
fnp-2971	214	12	(	(	PUNCT
fnp-2971	214	13	7	7	NUM
fnp-2971	214	14	)	)	PUNCT
fnp-2971	214	15	,	,	PUNCT
fnp-2971	214	16	while	while	SCONJ
fnp-2971	214	17	oosterhof	oosterhof	ADV
fnp-2971	214	18	et	et	PROPN
fnp-2971	214	19	al	al	PROPN
fnp-2971	214	20	.	.	PROPN
fnp-2971	214	21	found	find	VERB
fnp-2971	214	22	that	that	SCONJ
fnp-2971	214	23	microglia	microglia	ADJ
fnp-2971	214	24	loss	loss	NOUN
fnp-2971	214	25	preceded	precede	VERB
fnp-2971	214	26	it	it	PRON
fnp-2971	214	27	(	(	PUNCT
fnp-2971	214	28	8)	8)	NUM
fnp-2971	214	29	;	;	PUNCT
fnp-2971	214	30	and	and	CCONJ
fnp-2971	214	31	4	4	X
fnp-2971	214	32	)	)	PUNCT
fnp-2971	214	33	csf1r	csf1r	NOUN
fnp-2971	214	34	haploinsufficiency	haploinsufficiency	NOUN
fnp-2971	214	35	may	may	AUX
fnp-2971	214	36	lead	lead	VERB
fnp-2971	214	37	to	to	ADP
fnp-2971	214	38	the	the	DET
fnp-2971	214	39	maldistribution	maldistribution	NOUN
fnp-2971	214	40	of	of	ADP
fnp-2971	214	41	microglia	microglia	NOUN
fnp-2971	214	42	and	and	CCONJ
fnp-2971	214	43	result	result	VERB
fnp-2971	214	44	in	in	ADP
fnp-2971	214	45	the	the	DET
fnp-2971	214	46	regional	regional	ADJ
fnp-2971	214	47	loss	loss	NOUN
fnp-2971	214	48	(	(	PUNCT
fnp-2971	214	49	8)	8)	NUM
fnp-2971	214	50	.	.	PUNCT
fnp-2971	215	1	there	there	PRON
fnp-2971	215	2	are	be	VERB
fnp-2971	215	3	many	many	ADJ
fnp-2971	215	4	different	different	ADJ
fnp-2971	215	5	ways	way	NOUN
fnp-2971	215	6	to	to	PART
fnp-2971	215	7	associate	associate	VERB
fnp-2971	215	8	the	the	DET
fnp-2971	215	9	previous	previous	ADJ
fnp-2971	215	10	observations	observation	NOUN
fnp-2971	215	11	and	and	CCONJ
fnp-2971	215	12	conclusions	conclusion	NOUN
fnp-2971	215	13	about	about	ADP
fnp-2971	215	14	the	the	DET
fnp-2971	215	15	lesions	lesion	NOUN
fnp-2971	215	16	in	in	ADP
fnp-2971	215	17	alas	ala	NOUN
fnp-2971	215	18	with	with	ADP
fnp-2971	215	19	meaningful	meaningful	ADJ
fnp-2971	215	20	pathogenesis	pathogenesis	NOUN
fnp-2971	215	21	.	.	PUNCT
fnp-2971	216	1	we	we	PRON
fnp-2971	216	2	propose	propose	VERB
fnp-2971	216	3	the	the	DET
fnp-2971	216	4	following	follow	VERB
fnp-2971	216	5	pathogenesis	pathogenesis	NOUN
fnp-2971	216	6	:	:	PUNCT
fnp-2971	216	7	microglia	microglia	ADJ
fnp-2971	216	8	loss	loss	NOUN
fnp-2971	216	9	precedes	precede	VERB
fnp-2971	216	10	the	the	DET
fnp-2971	216	11	axonal	axonal	ADJ
fnp-2971	216	12	pathology	pathology	NOUN
fnp-2971	216	13	and	and	CCONJ
fnp-2971	216	14	most	most	ADV
fnp-2971	216	15	likely	likely	ADV
fnp-2971	216	16	represents	represent	VERB
fnp-2971	216	17	an	an	DET
fnp-2971	216	18	early	early	ADJ
fnp-2971	216	19	stage	stage	NOUN
fnp-2971	216	20	of	of	ADP
fnp-2971	216	21	the	the	DET
fnp-2971	216	22	pathology	pathology	NOUN
fnp-2971	216	23	.	.	PUNCT
fnp-2971	217	1	however	however	ADV
fnp-2971	217	2	,	,	PUNCT
fnp-2971	217	3	it	it	PRON
fnp-2971	217	4	is	be	AUX
fnp-2971	217	5	still	still	ADV
fnp-2971	217	6	unclear	unclear	ADJ
fnp-2971	217	7	what	what	PRON
fnp-2971	217	8	causes	cause	VERB
fnp-2971	217	9	axonal	axonal	ADJ
fnp-2971	217	10	injuries	injury	NOUN
fnp-2971	217	11	to	to	PART
fnp-2971	217	12	develop	develop	VERB
fnp-2971	217	13	in	in	ADP
fnp-2971	217	14	these	these	DET
fnp-2971	217	15	restricted	restrict	VERB
fnp-2971	217	16	areas	area	NOUN
fnp-2971	217	17	(	(	PUNCT
fnp-2971	217	18	and	and	CCONJ
fnp-2971	217	19	how	how	SCONJ
fnp-2971	217	20	)	)	PUNCT
fnp-2971	217	21	,	,	PUNCT
fnp-2971	217	22	and	and	CCONJ
fnp-2971	217	23	whether	whether	SCONJ
fnp-2971	217	24	this	this	DET
fnp-2971	217	25	progression	progression	NOUN
fnp-2971	217	26	occurs	occur	VERB
fnp-2971	217	27	with	with	ADP
fnp-2971	217	28	time	time	NOUN
fnp-2971	217	29	only	only	ADV
fnp-2971	217	30	(	(	PUNCT
fnp-2971	217	31	e.g.	e.g.	ADV
fnp-2971	217	32	aging	age	VERB
fnp-2971	217	33	process	process	NOUN
fnp-2971	217	34	)	)	PUNCT
fnp-2971	217	35	or	or	CCONJ
fnp-2971	217	36	if	if	SCONJ
fnp-2971	217	37	an	an	DET
fnp-2971	217	38	additional	additional	ADJ
fnp-2971	217	39	etiology	etiology	NOUN
fnp-2971	217	40	(	(	PUNCT
fnp-2971	217	41	e.g.	e.g.	ADV
fnp-2971	217	42	hypoperfusion	hypoperfusion	NOUN
fnp-2971	217	43	)	)	PUNCT
fnp-2971	217	44	is	be	AUX
fnp-2971	217	45	required	require	VERB
fnp-2971	217	46	.	.	PUNCT
fnp-2971	218	1	axonal	axonal	ADJ
fnp-2971	218	2	injuries	injury	NOUN
fnp-2971	218	3	that	that	PRON
fnp-2971	218	4	result	result	VERB
fnp-2971	218	5	in	in	ADP
fnp-2971	218	6	axonal	axonal	ADJ
fnp-2971	218	7	spheroids	spheroid	NOUN
fnp-2971	218	8	formation	formation	NOUN
fnp-2971	218	9	have	have	VERB
fnp-2971	218	10	many	many	ADJ
fnp-2971	218	11	causes	cause	NOUN
fnp-2971	218	12	,	,	PUNCT
fnp-2971	218	13	including	include	VERB
fnp-2971	218	14	hypoxic	hypoxic	ADV
fnp-2971	218	15	-	-	PUNCT
fnp-2971	218	16	ischemic	ischemic	ADJ
fnp-2971	218	17	,	,	PUNCT
fnp-2971	218	18	metabolic	metabolic	NOUN
fnp-2971	218	19	,	,	PUNCT
fnp-2971	218	20	toxic	toxic	ADJ
fnp-2971	218	21	,	,	PUNCT
fnp-2971	218	22	and	and	CCONJ
fnp-2971	218	23	traumatic	traumatic	ADJ
fnp-2971	218	24	causes	cause	NOUN
fnp-2971	218	25	.	.	PUNCT
fnp-2971	219	1	in	in	ADP
fnp-2971	219	2	previous	previous	ADJ
fnp-2971	219	3	studies	study	NOUN
fnp-2971	219	4	of	of	ADP
fnp-2971	219	5	alas	ala	NOUN
fnp-2971	219	6	,	,	PUNCT
fnp-2971	219	7	evidence	evidence	NOUN
fnp-2971	219	8	of	of	ADP
fnp-2971	219	9	oxidative	oxidative	ADJ
fnp-2971	219	10	stress	stress	NOUN
fnp-2971	219	11	caused	cause	VERB
fnp-2971	219	12	by	by	ADP
fnp-2971	219	13	hypoxic	hypoxic	ADJ
fnp-2971	219	14	-	-	PUNCT
fnp-2971	219	15	ischemic	ischemic	ADJ
fnp-2971	219	16	etiology	etiology	NOUN
fnp-2971	219	17	was	be	AUX
fnp-2971	219	18	presented	present	VERB
fnp-2971	219	19	(	(	PUNCT
fnp-2971	219	20	32	32	NUM
fnp-2971	219	21	,	,	PUNCT
fnp-2971	219	22	33	33	NUM
fnp-2971	219	23	)	)	PUNCT
fnp-2971	219	24	and	and	CCONJ
fnp-2971	219	25	this	this	PRON
fnp-2971	219	26	may	may	AUX
fnp-2971	219	27	represent	represent	VERB
fnp-2971	219	28	possible	possible	ADJ
fnp-2971	219	29	additional	additional	ADJ
fnp-2971	219	30	etiological	etiological	ADJ
fnp-2971	219	31	factors	factor	NOUN
fnp-2971	219	32	in	in	ADP
fnp-2971	219	33	the	the	DET
fnp-2971	219	34	pathogenesis	pathogenesis	NOUN
fnp-2971	219	35	of	of	ADP
fnp-2971	219	36	alas	alas	INTJ
fnp-2971	219	37	.	.	PUNCT
fnp-2971	220	1	the	the	DET
fnp-2971	220	2	effects	effect	NOUN
fnp-2971	220	3	of	of	ADP
fnp-2971	220	4	hypoxic	hypoxic	ADJ
fnp-2971	220	5	-	-	PUNCT
fnp-2971	220	6	ischemic	ischemic	ADJ
fnp-2971	220	7	injury	injury	NOUN
fnp-2971	220	8	depend	depend	VERB
fnp-2971	220	9	on	on	ADP
fnp-2971	220	10	the	the	DET
fnp-2971	220	11	severity	severity	NOUN
fnp-2971	220	12	and	and	CCONJ
fnp-2971	220	13	the	the	DET
fnp-2971	220	14	duration	duration	NOUN
fnp-2971	220	15	of	of	ADP
fnp-2971	220	16	the	the	DET
fnp-2971	220	17	hypoxic	hypoxic	ADJ
fnp-2971	220	18	-	-	PUNCT
fnp-2971	220	19	ischemic	ischemic	ADJ
fnp-2971	220	20	events	event	NOUN
fnp-2971	220	21	.	.	PUNCT
fnp-2971	221	1	as	as	SCONJ
fnp-2971	221	2	there	there	PRON
fnp-2971	221	3	are	be	VERB
fnp-2971	221	4	no	no	DET
fnp-2971	221	5	morphological	morphological	ADJ
fnp-2971	221	6	features	feature	NOUN
fnp-2971	221	7	of	of	ADP
fnp-2971	221	8	moderate	moderate	ADJ
fnp-2971	221	9	to	to	ADP
fnp-2971	221	10	severe	severe	ADJ
fnp-2971	221	11	hypoxic	hypoxic	ADJ
fnp-2971	221	12	-	-	PUNCT
fnp-2971	221	13	ischemic	ischemic	ADJ
fnp-2971	221	14	injury	injury	NOUN
fnp-2971	221	15	in	in	ADP
fnp-2971	221	16	alas	alas	INTJ
fnp-2971	221	17	,	,	PUNCT
fnp-2971	221	18	and	and	CCONJ
fnp-2971	221	19	the	the	DET
fnp-2971	221	20	axonal	axonal	ADJ
fnp-2971	221	21	injuries	injury	NOUN
fnp-2971	221	22	are	be	AUX
fnp-2971	221	23	limited	limit	VERB
fnp-2971	221	24	to	to	ADP
fnp-2971	221	25	areas	area	NOUN
fnp-2971	221	26	of	of	ADP
fnp-2971	221	27	microglia	microglia	ADJ
fnp-2971	221	28	loss	loss	NOUN
fnp-2971	221	29	,	,	PUNCT
fnp-2971	221	30	we	we	PRON
fnp-2971	221	31	concluded	conclude	VERB
fnp-2971	221	32	that	that	SCONJ
fnp-2971	221	33	this	this	PRON
fnp-2971	221	34	should	should	AUX
fnp-2971	221	35	be	be	AUX
fnp-2971	221	36	viewed	view	VERB
fnp-2971	221	37	as	as	ADP
fnp-2971	221	38	a	a	DET
fnp-2971	221	39	mild	mild	ADJ
fnp-2971	221	40	form	form	NOUN
fnp-2971	221	41	of	of	ADP
fnp-2971	221	42	injury	injury	NOUN
fnp-2971	221	43	.	.	PUNCT
fnp-2971	222	1	one	one	NUM
fnp-2971	222	2	possible	possible	ADJ
fnp-2971	222	3	cause	cause	NOUN
fnp-2971	222	4	of	of	ADP
fnp-2971	222	5	mild	mild	ADJ
fnp-2971	222	6	hypoxic	hypoxic	ADJ
fnp-2971	222	7	-	-	PUNCT
fnp-2971	222	8	ischemic	ischemic	ADJ
fnp-2971	222	9	events	event	NOUN
fnp-2971	222	10	that	that	PRON
fnp-2971	222	11	occur	occur	VERB
fnp-2971	222	12	with	with	ADP
fnp-2971	222	13	aging	aging	NOUN
fnp-2971	222	14	is	be	AUX
fnp-2971	222	15	age	age	NOUN
fnp-2971	222	16	-	-	PUNCT
fnp-2971	222	17	related	relate	VERB
fnp-2971	222	18	cerebral	cerebral	ADJ
fnp-2971	222	19	hypoperfusion	hypoperfusion	NOUN
fnp-2971	222	20	(	(	PUNCT
fnp-2971	222	21	34	34	NUM
fnp-2971	222	22	)	)	PUNCT
fnp-2971	222	23	,	,	PUNCT
fnp-2971	222	24	which	which	PRON
fnp-2971	222	25	could	could	AUX
fnp-2971	222	26	potentially	potentially	ADV
fnp-2971	222	27	explain	explain	VERB
fnp-2971	222	28	the	the	DET
fnp-2971	222	29	delayed	delay	VERB
fnp-2971	222	30	presentation	presentation	NOUN
fnp-2971	222	31	and	and	CCONJ
fnp-2971	222	32	progression	progression	NOUN
fnp-2971	222	33	of	of	ADP
fnp-2971	222	34	lesions	lesion	NOUN
fnp-2971	222	35	in	in	ADP
fnp-2971	222	36	alas	alas	INTJ
fnp-2971	222	37	.	.	PUNCT
fnp-2971	223	1	we	we	PRON
fnp-2971	223	2	emphasize	emphasize	VERB
fnp-2971	223	3	that	that	SCONJ
fnp-2971	223	4	this	this	PRON
fnp-2971	223	5	is	be	AUX
fnp-2971	223	6	speculative	speculative	ADJ
fnp-2971	223	7	,	,	PUNCT
fnp-2971	223	8	and	and	CCONJ
fnp-2971	223	9	not	not	PART
fnp-2971	223	10	a	a	DET
fnp-2971	223	11	conclusion	conclusion	NOUN
fnp-2971	223	12	of	of	ADP
fnp-2971	223	13	this	this	DET
fnp-2971	223	14	study	study	NOUN
fnp-2971	223	15	,	,	PUNCT
fnp-2971	223	16	but	but	CCONJ
fnp-2971	223	17	it	it	PRON
fnp-2971	223	18	might	might	AUX
fnp-2971	223	19	be	be	AUX
fnp-2971	223	20	an	an	DET
fnp-2971	223	21	explanation	explanation	NOUN
fnp-2971	223	22	of	of	ADP
fnp-2971	223	23	the	the	DET
fnp-2971	223	24	observed	observe	VERB
fnp-2971	223	25	correlation	correlation	NOUN
fnp-2971	223	26	between	between	ADP
fnp-2971	223	27	the	the	DET
fnp-2971	223	28	axonal	axonal	ADJ
fnp-2971	223	29	pathology	pathology	NOUN
fnp-2971	223	30	and	and	CCONJ
fnp-2971	223	31	the	the	DET
fnp-2971	223	32	microglial	microglial	ADJ
fnp-2971	223	33	loss	loss	NOUN
fnp-2971	223	34	.	.	PUNCT
fnp-2971	224	1	however	however	ADV
fnp-2971	224	2	,	,	PUNCT
fnp-2971	224	3	this	this	DET
fnp-2971	224	4	proposed	propose	VERB
fnp-2971	224	5	pathogenesis	pathogenesis	NOUN
fnp-2971	224	6	indicates	indicate	VERB
fnp-2971	224	7	that	that	SCONJ
fnp-2971	224	8	progression	progression	NOUN
fnp-2971	224	9	of	of	ADP
fnp-2971	224	10	alas	alas	PRON
fnp-2971	224	11	is	be	AUX
fnp-2971	224	12	potentially	potentially	ADV
fnp-2971	224	13	preventable	preventable	ADJ
fnp-2971	224	14	through	through	ADP
fnp-2971	224	15	:	:	SYM
fnp-2971	224	16	1	1	NUM
fnp-2971	224	17	)	)	PUNCT
fnp-2971	224	18	replacement	replacement	NOUN
fnp-2971	224	19	of	of	ADP
fnp-2971	224	20	the	the	DET
fnp-2971	224	21	lost	lose	VERB
fnp-2971	224	22	ramified	ramified	ADJ
fnp-2971	224	23	microglia	microglia	NOUN
fnp-2971	224	24	to	to	PART
fnp-2971	224	25	prevent	prevent	VERB
fnp-2971	224	26	further	further	ADJ
fnp-2971	224	27	damage	damage	NOUN
fnp-2971	224	28	through	through	ADP
fnp-2971	224	29	their	their	PRON
fnp-2971	224	30	protective	protective	ADJ
fnp-2971	224	31	function	function	NOUN
fnp-2971	224	32	,	,	PUNCT
fnp-2971	224	33	and	and	CCONJ
fnp-2971	224	34	2	2	X
fnp-2971	224	35	)	)	PUNCT
fnp-2971	224	36	improving	improve	VERB
fnp-2971	224	37	or	or	CCONJ
fnp-2971	224	38	preventing	prevent	VERB
fnp-2971	224	39	the	the	DET
fnp-2971	224	40	reduced	reduce	VERB
fnp-2971	224	41	cerebral	cerebral	ADJ
fnp-2971	224	42	blood	blood	NOUN
fnp-2971	224	43	flow	flow	NOUN
fnp-2971	224	44	associated	associate	VERB
fnp-2971	224	45	with	with	ADP
fnp-2971	224	46	aging	aging	NOUN
fnp-2971	224	47	.	.	PUNCT
fnp-2971	225	1	the	the	DET
fnp-2971	225	2	first	first	ADJ
fnp-2971	225	3	suggestion	suggestion	NOUN
fnp-2971	225	4	supports	support	VERB
fnp-2971	225	5	the	the	DET
fnp-2971	225	6	promising	promising	ADJ
fnp-2971	225	7	results	result	NOUN
fnp-2971	225	8	from	from	ADP
fnp-2971	225	9	allogeneic	allogeneic	ADJ
fnp-2971	225	10	haematopoietic	haematopoietic	ADJ
fnp-2971	225	11	stem	stem	NOUN
fnp-2971	225	12	cell	cell	NOUN
fnp-2971	225	13	transplantation	transplantation	NOUN
fnp-2971	225	14	(	(	PUNCT
fnp-2971	225	15	to	to	PART
fnp-2971	225	16	repopulate	repopulate	VERB
fnp-2971	225	17	the	the	DET
fnp-2971	225	18	microglial	microglial	ADJ
fnp-2971	225	19	niche	niche	NOUN
fnp-2971	225	20	)	)	PUNCT
fnp-2971	225	21	in	in	ADP
fnp-2971	225	22	patients	patient	NOUN
fnp-2971	225	23	with	with	ADP
fnp-2971	225	24	alas	alas	PROPN
fnp-2971	225	25	(	(	PUNCT
fnp-2971	225	26	35	35	NUM
fnp-2971	225	27	,	,	PUNCT
fnp-2971	225	28	36	36	NUM
fnp-2971	225	29	)	)	PUNCT
fnp-2971	225	30	.	.	PUNCT
fnp-2971	226	1	the	the	DET
fnp-2971	226	2	second	second	ADJ
fnp-2971	226	3	suggestion	suggestion	NOUN
fnp-2971	226	4	is	be	AUX
fnp-2971	226	5	currently	currently	ADV
fnp-2971	226	6	unpractical	unpractical	ADJ
fnp-2971	226	7	,	,	PUNCT
fnp-2971	226	8	even	even	ADV
fnp-2971	226	9	in	in	ADP
fnp-2971	226	10	the	the	DET
fnp-2971	226	11	animal	animal	NOUN
fnp-2971	226	12	model	model	NOUN
fnp-2971	226	13	,	,	PUNCT
fnp-2971	226	14	but	but	CCONJ
fnp-2971	226	15	this	this	PRON
fnp-2971	226	16	may	may	AUX
fnp-2971	226	17	change	change	VERB
fnp-2971	226	18	in	in	ADP
fnp-2971	226	19	the	the	DET
fnp-2971	226	20	future	future	NOUN
fnp-2971	226	21	.	.	PUNCT
fnp-2971	227	1	limitation	limitation	NOUN
fnp-2971	227	2	of	of	ADP
fnp-2971	227	3	the	the	DET
fnp-2971	227	4	study	study	NOUN
fnp-2971	227	5	the	the	DET
fnp-2971	227	6	major	major	ADJ
fnp-2971	227	7	limitation	limitation	NOUN
fnp-2971	227	8	of	of	ADP
fnp-2971	227	9	this	this	DET
fnp-2971	227	10	study	study	NOUN
fnp-2971	227	11	was	be	AUX
fnp-2971	227	12	the	the	DET
fnp-2971	227	13	inability	inability	NOUN
fnp-2971	227	14	to	to	PART
fnp-2971	227	15	test	test	VERB
fnp-2971	227	16	for	for	ADP
fnp-2971	227	17	csf1r	csf1r	PROPN
fnp-2971	227	18	mutation	mutation	NOUN
fnp-2971	227	19	from	from	ADP
fnp-2971	227	20	the	the	DET
fnp-2971	227	21	paraffin	paraffin	NOUN
fnp-2971	227	22	sections	section	NOUN
fnp-2971	227	23	in	in	ADP
fnp-2971	227	24	four	four	NUM
fnp-2971	227	25	of	of	ADP
fnp-2971	227	26	the	the	DET
fnp-2971	227	27	six	six	NUM
fnp-2971	227	28	cases	case	NOUN
fnp-2971	227	29	.	.	PUNCT
fnp-2971	228	1	however	however	ADV
fnp-2971	228	2	,	,	PUNCT
fnp-2971	228	3	the	the	DET
fnp-2971	228	4	histopathological	histopathological	ADJ
fnp-2971	228	5	diagnosis	diagnosis	NOUN
fnp-2971	228	6	of	of	ADP
fnp-2971	228	7	alas	alas	PRON
fnp-2971	228	8	is	be	AUX
fnp-2971	228	9	reliable	reliable	ADJ
fnp-2971	228	10	and	and	CCONJ
fnp-2971	228	11	considered	consider	VERB
fnp-2971	228	12	the	the	DET
fnp-2971	228	13	current	current	ADJ
fnp-2971	228	14	gold	gold	NOUN
fnp-2971	228	15	standard	standard	NOUN
fnp-2971	228	16	as	as	SCONJ
fnp-2971	228	17	new	new	ADJ
fnp-2971	228	18	mutations	mutation	NOUN
fnp-2971	228	19	in	in	ADP
fnp-2971	228	20	different	different	ADJ
fnp-2971	228	21	genes	gene	NOUN
fnp-2971	228	22	are	be	AUX
fnp-2971	228	23	being	be	AUX
fnp-2971	228	24	discovered	discover	VERB
fnp-2971	228	25	in	in	ADP
fnp-2971	228	26	alas	alas	INTJ
fnp-2971	228	27	.	.	PUNCT
fnp-2971	229	1	the	the	DET
fnp-2971	229	2	pathological	pathological	ADJ
fnp-2971	229	3	features	feature	NOUN
fnp-2971	229	4	of	of	ADP
fnp-2971	229	5	all	all	DET
fnp-2971	229	6	cases	case	NOUN
fnp-2971	229	7	were	be	AUX
fnp-2971	229	8	similar	similar	ADJ
fnp-2971	229	9	and	and	CCONJ
fnp-2971	229	10	the	the	DET
fnp-2971	229	11	characteristic	characteristic	ADJ
fnp-2971	229	12	three	three	NUM
fnp-2971	229	13	pathological	pathological	ADJ
fnp-2971	229	14	stages	stage	NOUN
fnp-2971	229	15	were	be	AUX
fnp-2971	229	16	present	present	ADJ
fnp-2971	229	17	in	in	ADP
fnp-2971	229	18	all	all	DET
fnp-2971	229	19	cases	case	NOUN
fnp-2971	229	20	.	.	PUNCT
fnp-2971	230	1	there	there	PRON
fnp-2971	230	2	was	be	VERB
fnp-2971	230	3	no	no	DET
fnp-2971	230	4	difference	difference	NOUN
fnp-2971	230	5	in	in	ADP
fnp-2971	230	6	the	the	DET
fnp-2971	230	7	morphological	morphological	ADJ
fnp-2971	230	8	features	feature	NOUN
fnp-2971	230	9	between	between	ADP
fnp-2971	230	10	cases	case	NOUN
fnp-2971	230	11	with	with	ADP
fnp-2971	230	12	confirmed	confirm	VERB
fnp-2971	230	13	csf1r	csf1r	PROPN
fnp-2971	230	14	alterations	alteration	NOUN
fnp-2971	230	15	(	(	PUNCT
fnp-2971	230	16	case	case	NOUN
fnp-2971	230	17	5	5	NUM
fnp-2971	230	18	and	and	CCONJ
fnp-2971	230	19	6	6	NUM
fnp-2971	230	20	)	)	PUNCT
fnp-2971	230	21	,	,	PUNCT
fnp-2971	230	22	and	and	CCONJ
fnp-2971	230	23	cases	case	NOUN
fnp-2971	230	24	with	with	ADP
fnp-2971	230	25	no	no	DET
fnp-2971	230	26	genetic	genetic	ADJ
fnp-2971	230	27	confirmation	confirmation	NOUN
fnp-2971	230	28	(	(	PUNCT
fnp-2971	230	29	cases	case	NOUN
fnp-2971	230	30	1–4	1–4	NUM
fnp-2971	230	31	)	)	PUNCT
fnp-2971	230	32	.	.	PUNCT
fnp-2971	231	1	the	the	DET
fnp-2971	231	2	association	association	NOUN
fnp-2971	231	3	of	of	ADP
fnp-2971	231	4	microglia	microglia	ADJ
fnp-2971	231	5	distribution	distribution	NOUN
fnp-2971	231	6	to	to	ADP
fnp-2971	231	7	the	the	DET
fnp-2971	231	8	axonal	axonal	ADJ
fnp-2971	231	9	spheroids	spheroid	NOUN
fnp-2971	231	10	and	and	CCONJ
fnp-2971	231	11	the	the	DET
fnp-2971	231	12	pathological	pathological	ADJ
fnp-2971	231	13	stages	stage	NOUN
fnp-2971	231	14	were	be	AUX
fnp-2971	231	15	similar	similar	ADJ
fnp-2971	231	16	in	in	ADP
fnp-2971	231	17	all	all	DET
fnp-2971	231	18	cases	case	NOUN
fnp-2971	231	19	,	,	PUNCT
fnp-2971	231	20	as	as	ADV
fnp-2971	231	21	well	well	ADV
fnp-2971	231	22	(	(	PUNCT
fnp-2971	231	23	table	table	NOUN
fnp-2971	231	24	2	2	NUM
fnp-2971	231	25	)	)	PUNCT
fnp-2971	231	26	.	.	PUNCT
fnp-2971	232	1	our	our	PRON
fnp-2971	232	2	results	result	NOUN
fnp-2971	232	3	and	and	CCONJ
fnp-2971	232	4	conclusions	conclusion	NOUN
fnp-2971	232	5	in	in	ADP
fnp-2971	232	6	this	this	DET
fnp-2971	232	7	study	study	NOUN
fnp-2971	232	8	(	(	PUNCT
fnp-2971	232	9	i.e.	i.e.	X
fnp-2971	232	10	the	the	DET
fnp-2971	232	11	correlation	correlation	NOUN
fnp-2971	232	12	between	between	ADP
fnp-2971	232	13	microglia	microglia	ADJ
fnp-2971	232	14	loss	loss	NOUN
fnp-2971	232	15	and	and	CCONJ
fnp-2971	232	16	axonal	axonal	ADJ
fnp-2971	232	17	spheroids	spheroid	NOUN
fnp-2971	232	18	)	)	PUNCT
fnp-2971	232	19	are	be	AUX
fnp-2971	232	20	based	base	VERB
fnp-2971	232	21	on	on	ADP
fnp-2971	232	22	the	the	DET
fnp-2971	232	23	pathological	pathological	ADJ
fnp-2971	232	24	findings	finding	NOUN
fnp-2971	232	25	only	only	ADV
fnp-2971	232	26	,	,	PUNCT
fnp-2971	232	27	regardless	regardless	ADV
fnp-2971	232	28	of	of	ADP
fnp-2971	232	29	the	the	DET
fnp-2971	232	30	underlying	underlying	ADJ
fnp-2971	232	31	genetic	genetic	ADJ
fnp-2971	232	32	alterations	alteration	NOUN
fnp-2971	232	33	.	.	PUNCT
fnp-2971	233	1	as	as	ADP
fnp-2971	233	2	such	such	ADJ
fnp-2971	233	3	,	,	PUNCT
fnp-2971	233	4	this	this	DET
fnp-2971	233	5	limitation	limitation	NOUN
fnp-2971	233	6	should	should	AUX
fnp-2971	233	7	not	not	PART
fnp-2971	233	8	depreciate	depreciate	VERB
fnp-2971	233	9	our	our	PRON
fnp-2971	233	10	results	result	NOUN
fnp-2971	233	11	and	and	CCONJ
fnp-2971	233	12	conclusions	conclusion	NOUN
fnp-2971	233	13	.	.	PUNCT
fnp-2971	234	1	however	however	ADV
fnp-2971	234	2	,	,	PUNCT
fnp-2971	234	3	it	it	PRON
fnp-2971	234	4	restricted	restrict	VERB
fnp-2971	234	5	our	our	PRON
fnp-2971	234	6	ability	ability	NOUN
fnp-2971	234	7	to	to	PART
fnp-2971	234	8	study	study	VERB
fnp-2971	234	9	the	the	DET
fnp-2971	234	10	correlation	correlation	NOUN
fnp-2971	234	11	between	between	ADP
fnp-2971	234	12	csf1r	csf1r	PROPN
fnp-2971	234	13	mutation	mutation	NOUN
fnp-2971	234	14	and	and	CCONJ
fnp-2971	234	15	the	the	DET
fnp-2971	234	16	morphological	morphological	ADJ
fnp-2971	234	17	changes	change	NOUN
fnp-2971	234	18	.	.	PUNCT
fnp-2971	235	1	conclusions	conclusion	NOUN
fnp-2971	235	2	the	the	DET
fnp-2971	235	3	main	main	ADJ
fnp-2971	235	4	finding	finding	NOUN
fnp-2971	235	5	of	of	ADP
fnp-2971	235	6	this	this	DET
fnp-2971	235	7	study	study	NOUN
fnp-2971	235	8	is	be	AUX
fnp-2971	235	9	a	a	DET
fnp-2971	235	10	multifocal	multifocal	ADJ
fnp-2971	235	11	loss	loss	NOUN
fnp-2971	235	12	of	of	ADP
fnp-2971	235	13	ramified	ramified	ADJ
fnp-2971	235	14	microglia	microglia	NOUN
fnp-2971	235	15	in	in	ADP
fnp-2971	235	16	alas	alas	INTJ
fnp-2971	235	17	.	.	PUNCT
fnp-2971	236	1	this	this	DET
fnp-2971	236	2	loss	loss	NOUN
fnp-2971	236	3	was	be	AUX
fnp-2971	236	4	seen	see	VERB
fnp-2971	236	5	in	in	ADP
fnp-2971	236	6	the	the	DET
fnp-2971	236	7	affected	affect	VERB
fnp-2971	236	8	areas	area	NOUN
fnp-2971	236	9	of	of	ADP
fnp-2971	236	10	all	all	DET
fnp-2971	236	11	pathological	pathological	ADJ
fnp-2971	236	12	stages	stage	NOUN
fnp-2971	236	13	and	and	CCONJ
fnp-2971	236	14	best	well	ADV
fnp-2971	236	15	correlated	correlate	VERB
fnp-2971	236	16	with	with	ADP
fnp-2971	236	17	the	the	DET
fnp-2971	236	18	presence	presence	NOUN
fnp-2971	236	19	of	of	ADP
fnp-2971	236	20	axonal	axonal	ADJ
fnp-2971	236	21	spheroids	spheroid	NOUN
fnp-2971	236	22	.	.	PUNCT
fnp-2971	237	1	the	the	DET
fnp-2971	237	2	presence	presence	NOUN
fnp-2971	237	3	of	of	ADP
fnp-2971	237	4	dense	dense	ADJ
fnp-2971	237	5	ramified	ramified	ADJ
fnp-2971	237	6	microglia	microglia	NOUN
fnp-2971	237	7	was	be	AUX
fnp-2971	237	8	associated	associate	VERB
fnp-2971	237	9	with	with	ADP
fnp-2971	237	10	better	well	ADJ
fnp-2971	237	11	preservation	preservation	NOUN
fnp-2971	237	12	of	of	ADP
fnp-2971	237	13	the	the	DET
fnp-2971	237	14	white	white	ADJ
fnp-2971	237	15	matter	matter	NOUN
fnp-2971	237	16	.	.	PUNCT
fnp-2971	238	1	we	we	PRON
fnp-2971	238	2	concluded	conclude	VERB
fnp-2971	238	3	that	that	SCONJ
fnp-2971	238	4	ramified	ramify	VERB
fnp-2971	238	5	microglia	microglia	NOUN
fnp-2971	238	6	most	most	ADV
fnp-2971	238	7	likely	likely	ADV
fnp-2971	238	8	have	have	VERB
fnp-2971	238	9	a	a	DET
fnp-2971	238	10	protective	protective	ADJ
fnp-2971	238	11	function	function	NOUN
fnp-2971	238	12	for	for	ADP
fnp-2971	238	13	the	the	DET
fnp-2971	238	14	white	white	ADJ
fnp-2971	238	15	matter	matter	NOUN
fnp-2971	238	16	and	and	CCONJ
fnp-2971	238	17	that	that	SCONJ
fnp-2971	238	18	their	their	PRON
fnp-2971	238	19	absence	absence	NOUN
fnp-2971	238	20	contributes	contribute	VERB
fnp-2971	238	21	to	to	ADP
fnp-2971	238	22	axonal	axonal	ADJ
fnp-2971	238	23	pathology	pathology	NOUN
fnp-2971	238	24	observed	observe	VERB
fnp-2971	238	25	in	in	ADP
fnp-2971	238	26	alas	alas	INTJ
fnp-2971	238	27	.	.	PUNCT
fnp-2971	239	1	these	these	DET
fnp-2971	239	2	findings	finding	NOUN
fnp-2971	239	3	will	will	AUX
fnp-2971	239	4	contribute	contribute	VERB
fnp-2971	239	5	to	to	ADP
fnp-2971	239	6	a	a	DET
fnp-2971	239	7	better	well	ADJ
fnp-2971	239	8	understanding	understanding	NOUN
fnp-2971	239	9	of	of	ADP
fnp-2971	239	10	the	the	DET
fnp-2971	239	11	pathogenesis	pathogenesis	NOUN
fnp-2971	239	12	of	of	ADP
fnp-2971	239	13	alas	alas	PRON
fnp-2971	239	14	and	and	CCONJ
fnp-2971	239	15	the	the	DET
fnp-2971	239	16	protective	protective	ADJ
fnp-2971	239	17	roles	role	NOUN
fnp-2971	239	18	of	of	ADP
fnp-2971	239	19	microglia	microglia	NOUN
fnp-2971	239	20	,	,	PUNCT
fnp-2971	239	21	thus	thus	ADV
fnp-2971	239	22	providing	provide	VERB
fnp-2971	239	23	possible	possible	ADJ
fnp-2971	239	24	areas	area	NOUN
fnp-2971	239	25	of	of	ADP
fnp-2971	239	26	intervention	intervention	NOUN
fnp-2971	239	27	to	to	PART
fnp-2971	239	28	prevent	prevent	VERB
fnp-2971	239	29	the	the	DET
fnp-2971	239	30	progression	progression	NOUN
fnp-2971	239	31	of	of	ADP
fnp-2971	239	32	the	the	DET
fnp-2971	239	33	disease	disease	NOUN
fnp-2971	239	34	.	.	PUNCT
fnp-2971	240	1	acknowledgments	acknowledgment	NOUN
fnp-2971	240	2	we	we	PRON
fnp-2971	240	3	are	be	AUX
fnp-2971	240	4	grateful	grateful	ADJ
fnp-2971	240	5	for	for	ADP
fnp-2971	240	6	the	the	DET
fnp-2971	240	7	contributions	contribution	NOUN
fnp-2971	240	8	of	of	ADP
fnp-2971	240	9	professor	professor	NOUN
fnp-2971	240	10	v.	v.	PROPN
fnp-2971	240	11	wee	wee	PROPN
fnp-2971	240	12	yong	yong	PROPN
fnp-2971	240	13	,	,	PUNCT
fnp-2971	240	14	university	university	PROPN
fnp-2971	240	15	of	of	ADP
fnp-2971	240	16	calgary	calgary	PROPN
fnp-2971	240	17	and	and	CCONJ
fnp-2971	240	18	hotchkiss	hotchkiss	PROPN
fnp-2971	240	19	brain	brain	PROPN
fnp-2971	240	20	institute	institute	PROPN
fnp-2971	240	21	,	,	PUNCT
fnp-2971	240	22	alberta	alberta	PROPN
fnp-2971	240	23	,	,	PUNCT
fnp-2971	240	24	canada	canada	PROPN
fnp-2971	240	25	(	(	PUNCT
fnp-2971	240	26	performing	perform	VERB
fnp-2971	240	27	iba1	iba1	PROPN
fnp-2971	240	28	immunohistochemistry	immunohistochemistry	NOUN
fnp-2971	240	29	)	)	PUNCT
fnp-2971	240	30	,	,	PUNCT
fnp-2971	240	31	the	the	DET
fnp-2971	240	32	neuropathology	neuropathology	NOUN
fnp-2971	240	33	technologists	technologist	NOUN
fnp-2971	240	34	at	at	ADP
fnp-2971	240	35	the	the	DET
fnp-2971	240	36	london	london	PROPN
fnp-2971	240	37	health	health	PROPN
fnp-2971	240	38	sciences	sciences	PROPN
fnp-2971	240	39	centre	centre	PROPN
fnp-2971	240	40	,	,	PUNCT
fnp-2971	240	41	ontario	ontario	PROPN
fnp-2971	240	42	,	,	PUNCT
fnp-2971	240	43	canada	canada	PROPN
fnp-2971	240	44	(	(	PUNCT
fnp-2971	240	45	technical	technical	ADJ
fnp-2971	240	46	support	support	NOUN
fnp-2971	240	47	)	)	PUNCT
fnp-2971	240	48	,	,	PUNCT
fnp-2971	240	49	dr	dr	PROPN
fnp-2971	240	50	.	.	PROPN
fnp-2971	240	51	ashraf	ashraf	PROPN
fnp-2971	240	52	dallol	dallol	PROPN
fnp-2971	240	53	,	,	PUNCT
fnp-2971	240	54	king	king	PROPN
fnp-2971	240	55	abdulaziz	abdulaziz	PROPN
fnp-2971	240	56	university	university	PROPN
fnp-2971	240	57	,	,	PUNCT
fnp-2971	240	58	jeddah	jeddah	PROPN
fnp-2971	240	59	,	,	PUNCT
fnp-2971	240	60	saudi	saudi	PROPN
fnp-2971	240	61	arabia	arabia	PROPN
fnp-2971	240	62	(	(	PUNCT
fnp-2971	240	63	interpretation	interpretation	NOUN
fnp-2971	240	64	of	of	ADP
fnp-2971	240	65	genetic	genetic	ADJ
fnp-2971	240	66	data	datum	NOUN
fnp-2971	240	67	)	)	PUNCT
fnp-2971	240	68	and	and	CCONJ
fnp-2971	240	69	the	the	DET
fnp-2971	240	70	department	department	NOUN
fnp-2971	240	71	of	of	ADP
fnp-2971	240	72	pathology	pathology	PROPN
fnp-2971	240	73	,	,	PUNCT
fnp-2971	240	74	western	western	ADJ
fnp-2971	240	75	university	university	NOUN
fnp-2971	240	76	,	,	PUNCT
fnp-2971	240	77	ontario	ontario	PROPN
fnp-2971	240	78	,	,	PUNCT
fnp-2971	240	79	canada	canada	PROPN
fnp-2971	240	80	(	(	PUNCT
fnp-2971	240	81	research	research	NOUN
fnp-2971	240	82	funding	funding	NOUN
fnp-2971	240	83	for	for	ADP
fnp-2971	240	84	lee	lee	PROPN
fnp-2971	240	85	-	-	PUNCT
fnp-2971	240	86	cyn	cyn	PROPN
fnp-2971	240	87	ang	ang	PROPN
fnp-2971	240	88	)	)	PUNCT
fnp-2971	240	89	.	.	PUNCT
fnp-2971	241	1	part	part	NOUN
fnp-2971	241	2	of	of	ADP
fnp-2971	241	3	this	this	DET
fnp-2971	241	4	work	work	NOUN
fnp-2971	241	5	was	be	AUX
fnp-2971	241	6	presented	present	VERB
fnp-2971	241	7	as	as	ADP
fnp-2971	241	8	a	a	DET
fnp-2971	241	9	poster	poster	NOUN
fnp-2971	241	10	at	at	ADP
fnp-2971	241	11	the	the	DET
fnp-2971	241	12	xixth	xixth	PROPN
fnp-2971	241	13	international	international	PROPN
fnp-2971	241	14	congress	congress	PROPN
fnp-2971	241	15	of	of	ADP
fnp-2971	241	16	neuropathology	neuropathology	NOUN
fnp-2971	241	17	,	,	PUNCT
fnp-2971	241	18	tokyo	tokyo	PROPN
fnp-2971	241	19	,	,	PUNCT
fnp-2971	241	20	september	september	PROPN
fnp-2971	241	21	23–27	23–27	NUM
fnp-2971	241	22	,	,	PUNCT
fnp-2971	241	23	2018	2018	NUM
fnp-2971	241	24	.	.	PUNCT
fnp-2971	242	1	references	reference	NOUN
fnp-2971	242	2	1	1	NUM
fnp-2971	242	3	.	.	PUNCT
fnp-2971	242	4	alturkustani	alturkustani	PROPN
fnp-2971	242	5	m	m	PROPN
fnp-2971	242	6	,	,	PUNCT
fnp-2971	242	7	keith	keith	PROPN
fnp-2971	242	8	j	j	PROPN
fnp-2971	242	9	,	,	PUNCT
fnp-2971	242	10	hazrati	hazrati	PROPN
fnp-2971	242	11	ln	ln	PROPN
fnp-2971	242	12	,	,	PUNCT
fnp-2971	242	13	rademakers	rademaker	NOUN
fnp-2971	242	14	r	r	NOUN
fnp-2971	242	15	,	,	PUNCT
fnp-2971	242	16	ang	ang	PROPN
fnp-2971	242	17	lc	lc	PROPN
fnp-2971	242	18	.	.	PUNCT
fnp-2971	242	19	pathologic	pathologic	ADJ
fnp-2971	242	20	staging	staging	NOUN
fnp-2971	242	21	of	of	ADP
fnp-2971	242	22	white	white	ADJ
fnp-2971	242	23	matter	matter	NOUN
fnp-2971	242	24	lesions	lesion	NOUN
fnp-2971	242	25	in	in	ADP
fnp-2971	242	26	adult	adult	NOUN
fnp-2971	242	27	-	-	PUNCT
fnp-2971	242	28	onset	onset	NOUN
fnp-2971	242	29	leukoencephalopathy	leukoencephalopathy	ADJ
fnp-2971	242	30	/	/	SYM
fnp-2971	242	31	leukodystrophy	leukodystrophy	NOUN
fnp-2971	242	32	with	with	ADP
fnp-2971	242	33	axonal	axonal	ADJ
fnp-2971	242	34	spheroids	spheroid	NOUN
fnp-2971	242	35	.	.	PUNCT
fnp-2971	243	1	j	j	PROPN
fnp-2971	243	2	neuropathol	neuropathol	PROPN
fnp-2971	243	3	exp	exp	PROPN
fnp-2971	243	4	neurol	neurol	PROPN
fnp-2971	243	5	2015:74;233	2015:74;233	NUM
fnp-2971	243	6	-	-	SYM
fnp-2971	243	7	40	40	NUM
fnp-2971	243	8	.	.	PUNCT
fnp-2971	244	1	2	2	X
fnp-2971	244	2	.	.	X
fnp-2971	244	3	alturkustani	alturkustani	PROPN
fnp-2971	244	4	m	m	PROPN
fnp-2971	244	5	,	,	PUNCT
fnp-2971	244	6	sharma	sharma	PROPN
fnp-2971	244	7	m	m	PROPN
fnp-2971	244	8	,	,	PUNCT
fnp-2971	244	9	hammond	hammond	PROPN
fnp-2971	244	10	r	r	PROPN
fnp-2971	244	11	,	,	PUNCT
fnp-2971	244	12	ang	ang	PROPN
fnp-2971	244	13	lc	lc	PROPN
fnp-2971	244	14	.	.	PUNCT
fnp-2971	244	15	adult	adult	NOUN
fnp-2971	244	16	-	-	PUNCT
fnp-2971	244	17	onset	onset	NOUN
fnp-2971	244	18	leukodystrophy	leukodystrophy	NOUN
fnp-2971	244	19	:	:	PUNCT
fnp-2971	244	20	review	review	NOUN
fnp-2971	244	21	of	of	ADP
fnp-2971	244	22	3	3	NUM
fnp-2971	244	23	clinicopathologic	clinicopathologic	ADJ
fnp-2971	244	24	phenotypes	phenotype	NOUN
fnp-2971	244	25	and	and	CCONJ
fnp-2971	244	26	a	a	DET
fnp-2971	244	27	proposed	propose	VERB
fnp-2971	244	28	classification	classification	NOUN
fnp-2971	244	29	.	.	PUNCT
fnp-2971	245	1	j	j	PROPN
fnp-2971	245	2	neuropathol	neuropathol	PROPN
fnp-2971	245	3	exp	exp	PROPN
fnp-2971	245	4	neurol	neurol	NOUN
fnp-2971	245	5	2013:72;1090	2013:72;1090	PROPN
fnp-2971	245	6	-	-	SYM
fnp-2971	245	7	103	103	NUM
fnp-2971	245	8	.	.	PUNCT
fnp-2971	246	1	3	3	X
fnp-2971	246	2	.	.	X
fnp-2971	246	3	rademakers	rademaker	NOUN
fnp-2971	246	4	r	r	NOUN
fnp-2971	246	5	,	,	PUNCT
fnp-2971	246	6	baker	baker	PROPN
fnp-2971	246	7	m	m	PROPN
fnp-2971	246	8	,	,	PUNCT
fnp-2971	246	9	nicholson	nicholson	PROPN
fnp-2971	246	10	am	be	AUX
fnp-2971	246	11	,	,	PUNCT
fnp-2971	246	12	rutherford	rutherford	PROPN
fnp-2971	246	13	nj	nj	PROPN
fnp-2971	246	14	,	,	PUNCT
fnp-2971	246	15	finch	finch	PROPN
fnp-2971	246	16	n	n	CCONJ
fnp-2971	246	17	,	,	PUNCT
fnp-2971	246	18	soto	soto	NOUN
fnp-2971	246	19	-	-	PUNCT
fnp-2971	246	20	ortolaza	ortolaza	PROPN
fnp-2971	246	21	a	a	PRON
fnp-2971	246	22	,	,	PUNCT
fnp-2971	246	23	lash	lash	PROPN
fnp-2971	246	24	j	j	PROPN
fnp-2971	246	25	,	,	PUNCT
fnp-2971	246	26	wider	wide	ADJ
fnp-2971	246	27	c	c	NOUN
fnp-2971	246	28	,	,	PUNCT
fnp-2971	246	29	wojtas	wojta	NOUN
fnp-2971	246	30	a	a	PRON
fnp-2971	246	31	,	,	PUNCT
fnp-2971	246	32	dejesus	dejesus	PROPN
fnp-2971	246	33	-	-	PUNCT
fnp-2971	246	34	hernandez	hernandez	PROPN
fnp-2971	246	35	m	m	PROPN
fnp-2971	246	36	,	,	PUNCT
fnp-2971	246	37	adamson	adamson	PROPN
fnp-2971	246	38	j	j	PROPN
fnp-2971	246	39	,	,	PUNCT
fnp-2971	246	40	kouri	kouri	PROPN
fnp-2971	246	41	n	n	PROPN
fnp-2971	246	42	,	,	PUNCT
fnp-2971	246	43	sundal	sundal	NOUN
fnp-2971	246	44	c	c	NOUN
fnp-2971	246	45	,	,	PUNCT
fnp-2971	246	46	shuster	shuster	PROPN
fnp-2971	246	47	ea	ea	PROPN
fnp-2971	246	48	,	,	PUNCT
fnp-2971	246	49	aasly	aasly	ADV
fnp-2971	246	50	j	j	PROPN
fnp-2971	246	51	,	,	PUNCT
fnp-2971	246	52	mackenzie	mackenzie	PROPN
fnp-2971	246	53	j	j	PROPN
fnp-2971	246	54	,	,	PUNCT
fnp-2971	246	55	roeber	roeber	PROPN
fnp-2971	246	56	s	s	PROPN
fnp-2971	246	57	,	,	PUNCT
fnp-2971	246	58	kretzschmar	kretzschmar	PROPN
fnp-2971	246	59	ha	ha	PROPN
fnp-2971	246	60	,	,	PUNCT
fnp-2971	246	61	boeve	boeve	PROPN
fnp-2971	246	62	bf	bf	NOUN
fnp-2971	246	63	,	,	PUNCT
fnp-2971	246	64	knopman	knopman	NOUN
fnp-2971	246	65	ds	ds	PROPN
fnp-2971	246	66	,	,	PUNCT
fnp-2971	246	67	petersen	petersen	PROPN
fnp-2971	246	68	rc	rc	PROPN
fnp-2971	246	69	,	,	PUNCT
fnp-2971	246	70	cairns	cairns	PROPN
fnp-2971	246	71	nj	nj	PROPN
fnp-2971	246	72	,	,	PUNCT
fnp-2971	246	73	ghetti	ghetti	PROPN
fnp-2971	246	74	b	b	PROPN
fnp-2971	246	75	,	,	PUNCT
fnp-2971	246	76	spina	spina	NOUN
fnp-2971	246	77	s	s	PART
fnp-2971	246	78	,	,	PUNCT
fnp-2971	246	79	garbern	garbern	ADJ
fnp-2971	246	80	j	j	PROPN
fnp-2971	246	81	,	,	PUNCT
fnp-2971	246	82	tselis	tselis	PROPN
fnp-2971	246	83	ac	ac	PROPN
fnp-2971	246	84	,	,	PUNCT
fnp-2971	246	85	uitti	uitti	ADJ
fnp-2971	246	86	r	r	NOUN
fnp-2971	246	87	,	,	PUNCT
fnp-2971	246	88	das	das	PROPN
fnp-2971	246	89	p	p	X
fnp-2971	246	90	,	,	PUNCT
fnp-2971	246	91	van	van	PROPN
fnp-2971	246	92	gerpen	gerpen	PROPN
fnp-2971	246	93	ja	ja	PROPN
fnp-2971	246	94	,	,	PUNCT
fnp-2971	246	95	meschia	meschia	PROPN
fnp-2971	246	96	jf	jf	PROPN
fnp-2971	246	97	,	,	PUNCT
fnp-2971	246	98	levy	levy	NOUN
fnp-2971	246	99	s	s	PROPN
fnp-2971	246	100	,	,	PUNCT
fnp-2971	246	101	broderick	broderick	PROPN
fnp-2971	246	102	df	df	PROPN
fnp-2971	246	103	,	,	PUNCT
fnp-2971	246	104	graff	graff	PROPN
fnp-2971	246	105	-	-	PUNCT
fnp-2971	246	106	radford	radford	PROPN
fnp-2971	246	107	n	n	CCONJ
fnp-2971	246	108	,	,	PUNCT
fnp-2971	246	109	ross	ross	PROPN
fnp-2971	246	110	oa	oa	PROPN
fnp-2971	246	111	,	,	PUNCT
fnp-2971	246	112	miller	miller	PROPN
fnp-2971	246	113	bb	bb	PROPN
fnp-2971	246	114	,	,	PUNCT
fnp-2971	246	115	swerdlow	swerdlow	NOUN
fnp-2971	246	116	rh	rh	PROPN
fnp-2971	246	117	,	,	PUNCT
fnp-2971	246	118	dickson	dickson	PROPN
fnp-2971	246	119	dw	dw	PROPN
fnp-2971	246	120	,	,	PUNCT
fnp-2971	246	121	wszolek	wszolek	VERB
fnp-2971	246	122	zk	zk	PROPN
fnp-2971	246	123	.	.	PUNCT
fnp-2971	247	1	mutations	mutation	NOUN
fnp-2971	247	2	in	in	ADP
fnp-2971	247	3	the	the	DET
fnp-2971	247	4	colony	colony	NOUN
fnp-2971	247	5	stimulating	stimulate	VERB
fnp-2971	247	6	factor	factor	NOUN
fnp-2971	247	7	1	1	NUM
fnp-2971	247	8	receptor	receptor	NOUN
fnp-2971	247	9	(	(	PUNCT
fnp-2971	247	10	csf1r	csf1r	NOUN
fnp-2971	247	11	)	)	PUNCT
fnp-2971	247	12	gene	gene	NOUN
fnp-2971	247	13	cause	cause	VERB
fnp-2971	247	14	hereditary	hereditary	ADJ
fnp-2971	247	15	diffuse	diffuse	NOUN
fnp-2971	247	16	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	247	17	with	with	ADP
fnp-2971	247	18	spheroids	spheroid	NOUN
fnp-2971	247	19	.	.	PUNCT
fnp-2971	248	1	nat	nat	PROPN
fnp-2971	248	2	genet	genet	PROPN
fnp-2971	248	3	2012:44;200	2012:44;200	NUM
fnp-2971	248	4	-	-	SYM
fnp-2971	248	5	5	5	NUM
fnp-2971	248	6	.	.	NOUN
fnp-2971	248	7	4	4	NUM
fnp-2971	248	8	.	.	X
fnp-2971	248	9	tada	tada	PROPN
fnp-2971	248	10	m	m	PROPN
fnp-2971	248	11	,	,	PUNCT
fnp-2971	248	12	konno	konno	PROPN
fnp-2971	248	13	t	t	PROPN
fnp-2971	248	14	,	,	PUNCT
fnp-2971	248	15	tada	tada	PROPN
fnp-2971	248	16	m	m	PROPN
fnp-2971	248	17	,	,	PUNCT
fnp-2971	248	18	tezuka	tezuka	PROPN
fnp-2971	248	19	t	t	PROPN
fnp-2971	248	20	,	,	PUNCT
fnp-2971	248	21	miura	miura	PROPN
fnp-2971	248	22	t	t	PROPN
fnp-2971	248	23	,	,	PUNCT
fnp-2971	248	24	mezaki	mezaki	PROPN
fnp-2971	248	25	n	n	CCONJ
fnp-2971	248	26	,	,	PUNCT
fnp-2971	248	27	okazaki	okazaki	PROPN
fnp-2971	248	28	k	k	PROPN
fnp-2971	248	29	,	,	PUNCT
fnp-2971	248	30	arakawa	arakawa	PROPN
fnp-2971	248	31	m	m	PROPN
fnp-2971	248	32	,	,	PUNCT
fnp-2971	248	33	itoh	itoh	PROPN
fnp-2971	248	34	k	k	PROPN
fnp-2971	248	35	,	,	PUNCT
fnp-2971	248	36	yamamoto	yamamoto	PROPN
fnp-2971	248	37	t	t	PROPN
fnp-2971	248	38	,	,	PUNCT
fnp-2971	248	39	yokoo	yokoo	PROPN
fnp-2971	248	40	h	h	PROPN
fnp-2971	248	41	,	,	PUNCT
fnp-2971	248	42	yoshikura	yoshikura	NOUN
fnp-2971	248	43	n	n	NOUN
fnp-2971	248	44	,	,	PUNCT
fnp-2971	248	45	ishihara	ishihara	PROPN
fnp-2971	248	46	k	k	PROPN
fnp-2971	248	47	,	,	PUNCT
fnp-2971	248	48	horie	horie	PROPN
fnp-2971	248	49	m	m	PROPN
fnp-2971	248	50	,	,	PUNCT
fnp-2971	248	51	takebayashi	takebayashi	PROPN
fnp-2971	248	52	h	h	PROPN
fnp-2971	248	53	,	,	PUNCT
fnp-2971	248	54	toyoshima	toyoshima	PROPN
fnp-2971	248	55	y	y	PROPN
fnp-2971	248	56	,	,	PUNCT
fnp-2971	248	57	naito	naito	PROPN
fnp-2971	248	58	m	m	PROPN
fnp-2971	248	59	,	,	PUNCT
fnp-2971	248	60	onodera	onodera	NOUN
fnp-2971	248	61	o	o	NOUN
fnp-2971	248	62	,	,	PUNCT
fnp-2971	248	63	nishizawa	nishizawa	PROPN
fnp-2971	248	64	m	m	PROPN
fnp-2971	248	65	,	,	PUNCT
fnp-2971	248	66	takahashi	takahashi	PROPN
fnp-2971	248	67	h	h	PROPN
fnp-2971	248	68	,	,	PUNCT
fnp-2971	248	69	ikeuchi	ikeuchi	PROPN
fnp-2971	248	70	t	t	PROPN
fnp-2971	248	71	,	,	PUNCT
fnp-2971	248	72	kakita	kakita	PROPN
fnp-2971	248	73	a.	a.	PROPN
fnp-2971	248	74	characteristic	characteristic	PROPN
fnp-2971	248	75	microglial	microglial	ADJ
fnp-2971	248	76	features	feature	NOUN
fnp-2971	248	77	in	in	ADP
fnp-2971	248	78	patients	patient	NOUN
fnp-2971	248	79	with	with	ADP
fnp-2971	248	80	hereditary	hereditary	ADJ
fnp-2971	248	81	diffuse	diffuse	NOUN
fnp-2971	248	82	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	248	83	with	with	ADP
fnp-2971	248	84	spheroids	spheroid	NOUN
fnp-2971	248	85	.	.	PUNCT
fnp-2971	249	1	ann	ann	PROPN
fnp-2971	249	2	neurol	neurol	PROPN
fnp-2971	249	3	2016:80;554	2016:80;554	NUM
fnp-2971	249	4	-	-	SYM
fnp-2971	249	5	65	65	NUM
fnp-2971	249	6	.	.	PUNCT
fnp-2971	249	7	5	5	NUM
fnp-2971	249	8	.	.	X
fnp-2971	249	9	streit	streit	PROPN
fnp-2971	249	10	wj	wj	PROPN
fnp-2971	249	11	,	,	PUNCT
fnp-2971	249	12	xue	xue	PROPN
fnp-2971	249	13	qs	qs	PROPN
fnp-2971	249	14	,	,	PUNCT
fnp-2971	249	15	tischer	tischer	PROPN
fnp-2971	249	16	j	j	PROPN
fnp-2971	249	17	,	,	PUNCT
fnp-2971	249	18	bechmann	bechmann	PROPN
fnp-2971	249	19	i.	i.	PROPN
fnp-2971	249	20	microglial	microglial	PROPN
fnp-2971	249	21	pathology	pathology	PROPN
fnp-2971	249	22	.	.	PUNCT
fnp-2971	250	1	acta	acta	PROPN
fnp-2971	250	2	neuropathol	neuropathol	PROPN
fnp-2971	250	3	commun	commun	PROPN
fnp-2971	250	4	2014:2;142	2014:2;142	PROPN
fnp-2971	250	5	.	.	PUNCT
fnp-2971	251	1	6	6	X
fnp-2971	251	2	.	.	X
fnp-2971	251	3	riku	riku	PROPN
fnp-2971	251	4	y	y	PROPN
fnp-2971	251	5	,	,	PUNCT
fnp-2971	251	6	ando	ando	PROPN
fnp-2971	251	7	t	t	PROPN
fnp-2971	251	8	,	,	PUNCT
fnp-2971	251	9	goto	goto	NOUN
fnp-2971	251	10	y	y	PROPN
fnp-2971	251	11	,	,	PUNCT
fnp-2971	251	12	mano	mano	PROPN
fnp-2971	251	13	k	k	PROPN
fnp-2971	251	14	,	,	PUNCT
fnp-2971	251	15	iwasaki	iwasaki	PROPN
fnp-2971	251	16	y	y	PROPN
fnp-2971	251	17	,	,	PUNCT
fnp-2971	251	18	sobue	sobue	NOUN
fnp-2971	251	19	g	g	PROPN
fnp-2971	251	20	,	,	PUNCT
fnp-2971	251	21	yoshida	yoshida	PROPN
fnp-2971	251	22	m.	m.	PROPN
fnp-2971	251	23	early	early	ADJ
fnp-2971	251	24	pathologic	pathologic	ADJ
fnp-2971	251	25	changes	change	NOUN
fnp-2971	251	26	in	in	ADP
fnp-2971	251	27	hereditary	hereditary	ADJ
fnp-2971	251	28	diffuse	diffuse	NOUN
fnp-2971	251	29	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	251	30	with	with	ADP
fnp-2971	251	31	spheroids	spheroid	NOUN
fnp-2971	251	32	.	.	PUNCT
fnp-2971	252	1	j	j	PROPN
fnp-2971	252	2	neuropathol	neuropathol	PROPN
fnp-2971	252	3	exp	exp	PROPN
fnp-2971	252	4	neurol	neurol	PROPN
fnp-2971	252	5	2014:73;1183	2014:73;1183	NUM
fnp-2971	252	6	-	-	SYM
fnp-2971	252	7	90	90	NUM
fnp-2971	252	8	.	.	PUNCT
fnp-2971	253	1	7	7	X
fnp-2971	253	2	.	.	X
fnp-2971	253	3	oyanagi	oyanagi	PROPN
fnp-2971	253	4	k	k	PROPN
fnp-2971	253	5	,	,	PUNCT
fnp-2971	253	6	kinoshita	kinoshita	PROPN
fnp-2971	253	7	m	m	PROPN
fnp-2971	253	8	,	,	PUNCT
fnp-2971	253	9	suzuki	suzuki	PROPN
fnp-2971	253	10	-	-	NOUN
fnp-2971	253	11	kouyama	kouyama	PROPN
fnp-2971	253	12	e	e	NOUN
fnp-2971	253	13	,	,	PUNCT
fnp-2971	253	14	inoue	inoue	PROPN
fnp-2971	253	15	t	t	PROPN
fnp-2971	253	16	,	,	PUNCT
fnp-2971	253	17	nakahara	nakahara	ADJ
fnp-2971	253	18	a	a	PRON
fnp-2971	253	19	,	,	PUNCT
fnp-2971	253	20	tokiwai	tokiwai	PROPN
fnp-2971	253	21	m	m	PROPN
fnp-2971	253	22	,	,	PUNCT
fnp-2971	253	23	arai	arai	PROPN
fnp-2971	253	24	n	n	CCONJ
fnp-2971	253	25	,	,	PUNCT
fnp-2971	253	26	satoh	satoh	PROPN
fnp-2971	253	27	ji	ji	PROPN
fnp-2971	253	28	,	,	PUNCT
fnp-2971	253	29	aoki	aoki	PROPN
fnp-2971	253	30	n	n	PROPN
fnp-2971	253	31	,	,	PUNCT
fnp-2971	253	32	jinnai	jinnai	PROPN
fnp-2971	253	33	k	k	PROPN
fnp-2971	253	34	,	,	PUNCT
fnp-2971	253	35	yazawa	yazawa	PROPN
fnp-2971	254	1	i	i	PRON
fnp-2971	254	2	,	,	PUNCT
fnp-2971	254	3	arai	arai	PROPN
fnp-2971	254	4	k	k	PROPN
fnp-2971	254	5	,	,	PUNCT
fnp-2971	254	6	ishihara	ishihara	PROPN
fnp-2971	254	7	k	k	PROPN
fnp-2971	254	8	,	,	PUNCT
fnp-2971	254	9	kawamura	kawamura	PROPN
fnp-2971	254	10	m	m	PROPN
fnp-2971	254	11	,	,	PUNCT
fnp-2971	254	12	ishizawa	ishizawa	PROPN
fnp-2971	254	13	k	k	PROPN
fnp-2971	254	14	,	,	PUNCT
fnp-2971	254	15	hasegawa	hasegawa	PROPN
fnp-2971	254	16	k	k	PROPN
fnp-2971	254	17	,	,	PUNCT
fnp-2971	254	18	yagisita	yagisita	PROPN
fnp-2971	254	19	s	s	PROPN
fnp-2971	254	20	,	,	PUNCT
fnp-2971	254	21	amano	amano	PROPN
fnp-2971	254	22	n	n	PROPN
fnp-2971	254	23	,	,	PUNCT
fnp-2971	254	24	yoshida	yoshida	PROPN
fnp-2971	254	25	k	k	PROPN
fnp-2971	254	26	,	,	PUNCT
fnp-2971	254	27	terada	terada	PROPN
fnp-2971	254	28	s	s	PROPN
fnp-2971	254	29	,	,	PUNCT
fnp-2971	254	30	yoshida	yoshida	PROPN
fnp-2971	254	31	m	m	PROPN
fnp-2971	254	32	,	,	PUNCT
fnp-2971	254	33	akiyama	akiyama	PROPN
fnp-2971	254	34	h	h	PROPN
fnp-2971	254	35	,	,	PUNCT
fnp-2971	254	36	mitsuyama	mitsuyama	PROPN
fnp-2971	254	37	y	y	PROPN
fnp-2971	254	38	,	,	PUNCT
fnp-2971	254	39	ikeda	ikeda	PROPN
fnp-2971	254	40	si	si	PROPN
fnp-2971	254	41	.	.	PROPN
fnp-2971	254	42	adult	adult	NOUN
fnp-2971	254	43	onset	onset	NOUN
fnp-2971	254	44	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	254	45	with	with	ADP
fnp-2971	254	46	axonal	axonal	ADJ
fnp-2971	254	47	spheroids	spheroid	NOUN
fnp-2971	254	48	and	and	CCONJ
fnp-2971	254	49	pigmented	pigmented	ADJ
fnp-2971	254	50	glia	glia	NOUN
fnp-2971	254	51	(	(	PUNCT
fnp-2971	254	52	alsp	alsp	PROPN
fnp-2971	254	53	)	)	PUNCT
fnp-2971	254	54	and	and	CCONJ
fnp-2971	254	55	nasu	nasu	PROPN
fnp-2971	254	56	-	-	PUNCT
fnp-2971	254	57	hakola	hakola	PROPN
fnp-2971	254	58	disease	disease	NOUN
fnp-2971	254	59	:	:	PUNCT
fnp-2971	254	60	lesion	lesion	NOUN
fnp-2971	254	61	staging	staging	NOUN
fnp-2971	254	62	and	and	CCONJ
fnp-2971	254	63	dynamic	dynamic	ADJ
fnp-2971	254	64	changes	change	NOUN
fnp-2971	254	65	of	of	ADP
fnp-2971	254	66	axons	axon	NOUN
fnp-2971	254	67	and	and	CCONJ
fnp-2971	254	68	microglial	microglial	ADJ
fnp-2971	254	69	subsets	subset	NOUN
fnp-2971	254	70	.	.	PUNCT
fnp-2971	255	1	brain	brain	NOUN
fnp-2971	255	2	pathol	pathol	NOUN
fnp-2971	255	3	2017:27;748	2017:27;748	NUM
fnp-2971	255	4	-	-	SYM
fnp-2971	255	5	69	69	NUM
fnp-2971	255	6	.	.	PUNCT
fnp-2971	256	1	8	8	NUM
fnp-2971	256	2	.	.	NOUN
fnp-2971	256	3	oosterhof	oosterhof	NOUN
fnp-2971	256	4	n	n	CCONJ
fnp-2971	256	5	,	,	PUNCT
fnp-2971	256	6	kuil	kuil	PROPN
fnp-2971	256	7	le	le	PROPN
fnp-2971	256	8	,	,	PUNCT
fnp-2971	256	9	van	van	PROPN
fnp-2971	256	10	der	der	NOUN
fnp-2971	256	11	linde	linde	PROPN
fnp-2971	256	12	hc	hc	PROPN
fnp-2971	256	13	,	,	PUNCT
fnp-2971	256	14	burm	burm	PROPN
fnp-2971	256	15	sm	sm	PROPN
fnp-2971	256	16	,	,	PUNCT
fnp-2971	256	17	berdowski	berdowski	VERB
fnp-2971	256	18	w	w	PROPN
fnp-2971	256	19	,	,	PUNCT
fnp-2971	256	20	van	van	PROPN
fnp-2971	256	21	ijcken	ijcken	VERB
fnp-2971	256	22	wfj	wfj	PROPN
fnp-2971	256	23	,	,	PUNCT
fnp-2971	256	24	van	van	PROPN
fnp-2971	256	25	swieten	swieten	PROPN
fnp-2971	256	26	jc	jc	PROPN
fnp-2971	256	27	,	,	PUNCT
fnp-2971	256	28	hol	hol	VERB
fnp-2971	256	29	em	em	PRON
fnp-2971	256	30	,	,	PUNCT
fnp-2971	256	31	verheijen	verheijen	PROPN
fnp-2971	256	32	mhg	mhg	PROPN
fnp-2971	256	33	,	,	PUNCT
fnp-2971	256	34	van	van	PROPN
fnp-2971	256	35	ham	ham	PROPN
fnp-2971	256	36	tj	tj	PROPN
fnp-2971	256	37	.	.	PUNCT
fnp-2971	256	38	colony	colony	NOUN
fnp-2971	256	39	-	-	PUNCT
fnp-2971	256	40	stimulating	stimulate	VERB
fnp-2971	256	41	factor	factor	NOUN
fnp-2971	256	42	1	1	NUM
fnp-2971	256	43	receptor	receptor	NOUN
fnp-2971	256	44	(	(	PUNCT
fnp-2971	256	45	csf1r	csf1r	NOUN
fnp-2971	256	46	)	)	PUNCT
fnp-2971	256	47	regulates	regulate	VERB
fnp-2971	256	48	microglia	microglia	ADJ
fnp-2971	256	49	density	density	NOUN
fnp-2971	256	50	and	and	CCONJ
fnp-2971	256	51	distribution	distribution	NOUN
fnp-2971	256	52	,	,	PUNCT
fnp-2971	256	53	but	but	CCONJ
fnp-2971	256	54	not	not	PART
fnp-2971	256	55	microglia	microglia	ADJ
fnp-2971	256	56	differentiation	differentiation	NOUN
fnp-2971	256	57	in	in	ADP
fnp-2971	256	58	vivo	vivo	NOUN
fnp-2971	256	59	.	.	PUNCT
fnp-2971	257	1	cell	cell	NOUN
fnp-2971	257	2	rep	rep	PROPN
fnp-2971	257	3	2018:24;1203	2018:24;1203	NUM
fnp-2971	257	4	-	-	SYM
fnp-2971	257	5	17	17	NUM
fnp-2971	257	6	e6	e6	NOUN
fnp-2971	257	7	.	.	PUNCT
fnp-2971	258	1	9	9	X
fnp-2971	258	2	.	.	X
fnp-2971	259	1	sarkar	sarkar	PROPN
fnp-2971	259	2	s	s	PROPN
fnp-2971	259	3	,	,	PUNCT
fnp-2971	259	4	doring	dore	VERB
fnp-2971	259	5	a	a	DET
fnp-2971	259	6	,	,	PUNCT
fnp-2971	259	7	zemp	zemp	PROPN
fnp-2971	259	8	fj	fj	PROPN
fnp-2971	259	9	,	,	PUNCT
fnp-2971	259	10	silva	silva	PROPN
fnp-2971	259	11	c	c	PROPN
fnp-2971	259	12	,	,	PUNCT
fnp-2971	259	13	lun	lun	PROPN
fnp-2971	259	14	x	x	X
fnp-2971	259	15	,	,	PUNCT
fnp-2971	259	16	wang	wang	PROPN
fnp-2971	259	17	x	x	PROPN
fnp-2971	259	18	,	,	PUNCT
fnp-2971	259	19	kelly	kelly	PROPN
fnp-2971	259	20	j	j	PROPN
fnp-2971	259	21	,	,	PUNCT
fnp-2971	259	22	hader	hader	PROPN
fnp-2971	259	23	w	w	PROPN
fnp-2971	259	24	,	,	PUNCT
fnp-2971	259	25	hamilton	hamilton	PROPN
fnp-2971	259	26	m	m	PROPN
fnp-2971	259	27	,	,	PUNCT
fnp-2971	259	28	mercier	merci	ADJ
fnp-2971	259	29	p	p	PROPN
fnp-2971	259	30	,	,	PUNCT
fnp-2971	259	31	dunn	dunn	PROPN
fnp-2971	259	32	jf	jf	PROPN
fnp-2971	259	33	,	,	PUNCT
fnp-2971	259	34	kinniburgh	kinniburgh	PROPN
fnp-2971	259	35	d	d	PROPN
fnp-2971	259	36	,	,	PUNCT
fnp-2971	259	37	van	van	PROPN
fnp-2971	259	38	rooijen	rooijen	PROPN
fnp-2971	259	39	n	n	PROPN
fnp-2971	259	40	,	,	PUNCT
fnp-2971	259	41	robbins	robbins	PROPN
fnp-2971	259	42	s	s	PROPN
fnp-2971	259	43	,	,	PUNCT
fnp-2971	259	44	forsyth	forsyth	PROPN
fnp-2971	259	45	p	p	PROPN
fnp-2971	259	46	,	,	PUNCT
fnp-2971	259	47	cairncross	cairncross	ADV
fnp-2971	259	48	g	g	PROPN
fnp-2971	259	49	,	,	PUNCT
fnp-2971	259	50	weiss	weiss	PROPN
fnp-2971	259	51	s	s	PROPN
fnp-2971	259	52	,	,	PUNCT
fnp-2971	259	53	yong	yong	PROPN
fnp-2971	259	54	vw	vw	PROPN
fnp-2971	259	55	.	.	PUNCT
fnp-2971	260	1	therapeutic	therapeutic	ADJ
fnp-2971	260	2	activation	activation	NOUN
fnp-2971	260	3	of	of	ADP
fnp-2971	260	4	macrophages	macrophage	NOUN
fnp-2971	260	5	and	and	CCONJ
fnp-2971	260	6	microglia	microglia	ADJ
fnp-2971	260	7	to	to	PART
fnp-2971	260	8	suppress	suppress	VERB
fnp-2971	260	9	brain	brain	NOUN
fnp-2971	260	10	tumor	tumor	NOUN
fnp-2971	260	11	-	-	PUNCT
fnp-2971	260	12	initiating	initiate	VERB
fnp-2971	260	13	cells	cell	NOUN
fnp-2971	260	14	.	.	PUNCT
fnp-2971	261	1	nat	nat	PROPN
fnp-2971	261	2	neurosci	neurosci	PROPN
fnp-2971	261	3	2014:17;46	2014:17;46	PROPN
fnp-2971	261	4	-	-	SYM
fnp-2971	261	5	55	55	NUM
fnp-2971	261	6	.	.	PUNCT
fnp-2971	262	1	10	10	NUM
fnp-2971	262	2	.	.	PUNCT
fnp-2971	262	3	boche	boche	PROPN
fnp-2971	262	4	d	d	PROPN
fnp-2971	262	5	,	,	PUNCT
fnp-2971	262	6	perry	perry	PROPN
fnp-2971	262	7	vh	vh	PROPN
fnp-2971	262	8	,	,	PUNCT
fnp-2971	262	9	nicoll	nicoll	PROPN
fnp-2971	262	10	ja	ja	PROPN
fnp-2971	262	11	.	.	PROPN
fnp-2971	263	1	review	review	NOUN
fnp-2971	263	2	:	:	PUNCT
fnp-2971	263	3	activation	activation	NOUN
fnp-2971	263	4	patterns	pattern	NOUN
fnp-2971	263	5	of	of	ADP
fnp-2971	263	6	microglia	microglia	NOUN
fnp-2971	263	7	and	and	CCONJ
fnp-2971	263	8	their	their	PRON
fnp-2971	263	9	identification	identification	NOUN
fnp-2971	263	10	in	in	ADP
fnp-2971	263	11	the	the	DET
fnp-2971	263	12	human	human	ADJ
fnp-2971	263	13	brain	brain	NOUN
fnp-2971	263	14	.	.	PUNCT
fnp-2971	264	1	neuropathol	neuropathol	PROPN
fnp-2971	264	2	appl	appl	PROPN
fnp-2971	264	3	neurobiol	neurobiol	PROPN
fnp-2971	264	4	2013:39;3	2013:39;3	PROPN
fnp-2971	264	5	-	-	SYM
fnp-2971	264	6	18	18	NUM
fnp-2971	264	7	.	.	PUNCT
fnp-2971	264	8	11	11	NUM
fnp-2971	264	9	.	.	PUNCT
fnp-2971	265	1	taylor	taylor	PROPN
fnp-2971	265	2	r	r	PROPN
fnp-2971	265	3	,	,	PUNCT
fnp-2971	265	4	alyamany	alyamany	NOUN
fnp-2971	265	5	b	b	NUM
fnp-2971	265	6	,	,	PUNCT
fnp-2971	265	7	pandey	pandey	PROPN
fnp-2971	265	8	s	s	PROPN
fnp-2971	265	9	,	,	PUNCT
fnp-2971	265	10	kertesz	kertesz	NOUN
fnp-2971	265	11	a	a	NOUN
fnp-2971	265	12	,	,	PUNCT
fnp-2971	265	13	ang	ang	PROPN
fnp-2971	265	14	lc	lc	PROPN
fnp-2971	265	15	,	,	PUNCT
fnp-2971	266	1	finger	finger	PROPN
fnp-2971	266	2	e.	e.	PROPN
fnp-2971	266	3	two	two	NUM
fnp-2971	266	4	distinct	distinct	ADJ
fnp-2971	266	5	clinical	clinical	ADJ
fnp-2971	266	6	phenotypes	phenotype	NOUN
fnp-2971	266	7	in	in	ADP
fnp-2971	266	8	a	a	DET
fnp-2971	266	9	family	family	NOUN
fnp-2971	266	10	with	with	ADP
fnp-2971	266	11	alsp	alsp	PROPN
fnp-2971	266	12	caused	cause	VERB
fnp-2971	266	13	by	by	ADP
fnp-2971	266	14	a	a	DET
fnp-2971	266	15	novel	novel	ADJ
fnp-2971	266	16	csf-1r	csf-1r	NOUN
fnp-2971	266	17	mutation.(p2	mutation.(p2	PROPN
fnp-2971	266	18	.	.	PUNCT
fnp-2971	266	19	176	176	NUM
fnp-2971	266	20	)	)	PUNCT
fnp-2971	266	21	.	.	PUNCT
fnp-2971	267	1	aan	aan	PROPN
fnp-2971	267	2	enterprises	enterprise	NOUN
fnp-2971	267	3	,	,	PUNCT
fnp-2971	267	4	2018	2018	NUM
fnp-2971	267	5	.	.	PUNCT
fnp-2971	268	1	12	12	NUM
fnp-2971	268	2	.	.	PUNCT
fnp-2971	269	1	van	van	PROPN
fnp-2971	269	2	der	der	PROPN
fnp-2971	269	3	knaap	knaap	PROPN
fnp-2971	269	4	ms	ms	PROPN
fnp-2971	269	5	,	,	PUNCT
fnp-2971	269	6	bugiani	bugiani	PROPN
fnp-2971	269	7	m.	m.	PROPN
fnp-2971	269	8	leukodystrophies	leukodystrophies	PROPN
fnp-2971	269	9	:	:	PUNCT
fnp-2971	269	10	a	a	DET
fnp-2971	269	11	proposed	propose	VERB
fnp-2971	269	12	classification	classification	NOUN
fnp-2971	269	13	system	system	NOUN
fnp-2971	269	14	based	base	VERB
fnp-2971	269	15	on	on	ADP
fnp-2971	269	16	pathological	pathological	ADJ
fnp-2971	269	17	changes	change	NOUN
fnp-2971	269	18	and	and	CCONJ
fnp-2971	269	19	pathogenetic	pathogenetic	ADJ
fnp-2971	269	20	mechanisms	mechanism	NOUN
fnp-2971	269	21	.	.	PUNCT
fnp-2971	270	1	acta	acta	PROPN
fnp-2971	270	2	neuropathol	neuropathol	PROPN
fnp-2971	270	3	2017:134;351	2017:134;351	PROPN
fnp-2971	270	4	-	-	SYM
fnp-2971	270	5	82	82	NUM
fnp-2971	270	6	.	.	NOUN
fnp-2971	270	7	13	13	NUM
fnp-2971	270	8	.	.	PUNCT
fnp-2971	271	1	konno	konno	PROPN
fnp-2971	271	2	t	t	PROPN
fnp-2971	271	3	,	,	PUNCT
fnp-2971	271	4	kasanuki	kasanuki	PROPN
fnp-2971	271	5	k	k	PROPN
fnp-2971	271	6	,	,	PUNCT
fnp-2971	271	7	ikeuchi	ikeuchi	PROPN
fnp-2971	271	8	t	t	PROPN
fnp-2971	271	9	,	,	PUNCT
fnp-2971	271	10	dickson	dickson	PROPN
fnp-2971	271	11	dw	dw	PROPN
fnp-2971	271	12	,	,	PUNCT
fnp-2971	271	13	wszolek	wszolek	VERB
fnp-2971	271	14	zk	zk	PROPN
fnp-2971	271	15	.	.	PUNCT
fnp-2971	272	1	csf1r	csf1r	PROPN
fnp-2971	272	2	-	-	PUNCT
fnp-2971	272	3	related	relate	VERB
fnp-2971	272	4	leukoencephalopathy	leukoencephalopathy	NOUN
fnp-2971	272	5	:	:	PUNCT
fnp-2971	272	6	a	a	DET
fnp-2971	272	7	major	major	ADJ
fnp-2971	272	8	player	player	NOUN
fnp-2971	272	9	in	in	ADP
fnp-2971	272	10	primary	primary	ADJ
fnp-2971	272	11	microgliopathies	microgliopathie	NOUN
fnp-2971	272	12	.	.	PUNCT
fnp-2971	273	1	neurology	neurology	NOUN
fnp-2971	273	2	2018:91;1092	2018:91;1092	PROPN
fnp-2971	273	3	-	-	SYM
fnp-2971	273	4	104	104	NUM
fnp-2971	273	5	.	.	PUNCT
fnp-2971	273	6	14	14	NUM
fnp-2971	273	7	.	.	PUNCT
fnp-2971	274	1	lynch	lynch	PROPN
fnp-2971	274	2	ds	ds	PROPN
fnp-2971	274	3	,	,	PUNCT
fnp-2971	274	4	zhang	zhang	PROPN
fnp-2971	274	5	wj	wj	PROPN
fnp-2971	274	6	,	,	PUNCT
fnp-2971	274	7	lakshmanan	lakshmanan	PROPN
fnp-2971	274	8	r	r	PROPN
fnp-2971	274	9	,	,	PUNCT
fnp-2971	274	10	kinsella	kinsella	PROPN
fnp-2971	274	11	ja	ja	PROPN
fnp-2971	274	12	,	,	PUNCT
fnp-2971	274	13	uzun	uzun	PROPN
fnp-2971	274	14	ga	ga	PROPN
fnp-2971	274	15	,	,	PUNCT
fnp-2971	274	16	karbay	karbay	PROPN
fnp-2971	274	17	m	m	PROPN
fnp-2971	274	18	,	,	PUNCT
fnp-2971	274	19	tufekcioglu	tufekcioglu	PROPN
fnp-2971	274	20	z	z	PROPN
fnp-2971	274	21	,	,	PUNCT
fnp-2971	274	22	hanagasi	hanagasi	PROPN
fnp-2971	274	23	h	h	PROPN
fnp-2971	274	24	,	,	PUNCT
fnp-2971	274	25	burke	burke	PROPN
fnp-2971	274	26	g	g	PROPN
fnp-2971	274	27	,	,	PUNCT
fnp-2971	274	28	foulds	fould	NOUN
fnp-2971	274	29	n	n	CCONJ
fnp-2971	274	30	,	,	PUNCT
fnp-2971	274	31	hammans	hammans	PROPN
fnp-2971	274	32	sr	sr	PROPN
fnp-2971	274	33	,	,	PUNCT
fnp-2971	274	34	bhattacharjee	bhattacharjee	PROPN
fnp-2971	274	35	a	a	PROPN
fnp-2971	274	36	,	,	PUNCT
fnp-2971	274	37	wilson	wilson	PROPN
fnp-2971	274	38	h	h	PROPN
fnp-2971	274	39	,	,	PUNCT
fnp-2971	274	40	adams	adams	PROPN
fnp-2971	274	41	m	m	PROPN
fnp-2971	274	42	,	,	PUNCT
fnp-2971	274	43	walker	walker	PROPN
fnp-2971	274	44	m	m	PROPN
fnp-2971	274	45	,	,	PUNCT
fnp-2971	274	46	nicoll	nicoll	PROPN
fnp-2971	274	47	ja	ja	PROPN
fnp-2971	274	48	,	,	PUNCT
fnp-2971	274	49	chataway	chataway	PROPN
fnp-2971	274	50	j	j	PROPN
fnp-2971	274	51	,	,	PUNCT
fnp-2971	274	52	fox	fox	PROPN
fnp-2971	274	53	n	n	CCONJ
fnp-2971	274	54	,	,	PUNCT
fnp-2971	274	55	davagnanam	davagnanam	NOUN
fnp-2971	274	56	i	i	PRON
fnp-2971	274	57	,	,	PUNCT
fnp-2971	274	58	phadke	phadke	ADJ
fnp-2971	274	59	r	r	NOUN
fnp-2971	274	60	,	,	PUNCT
fnp-2971	274	61	houlden	houlden	ADJ
fnp-2971	274	62	h.	h.	NOUN
fnp-2971	274	63	analysis	analysis	NOUN
fnp-2971	274	64	of	of	ADP
fnp-2971	274	65	mutations	mutation	NOUN
fnp-2971	274	66	in	in	ADP
fnp-2971	274	67	aars2	aars2	NOUN
fnp-2971	274	68	in	in	ADP
fnp-2971	274	69	a	a	DET
fnp-2971	274	70	series	series	NOUN
fnp-2971	274	71	of	of	ADP
fnp-2971	274	72	csf1r	csf1r	NOUN
fnp-2971	274	73	-	-	ADJ
fnp-2971	274	74	negative	negative	ADJ
fnp-2971	274	75	patients	patient	NOUN
fnp-2971	274	76	with	with	ADP
fnp-2971	274	77	adult	adult	NOUN
fnp-2971	274	78	-	-	PUNCT
fnp-2971	274	79	onset	onset	NOUN
fnp-2971	274	80	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	274	81	with	with	ADP
fnp-2971	274	82	axonal	axonal	ADJ
fnp-2971	274	83	spheroids	spheroid	NOUN
fnp-2971	274	84	and	and	CCONJ
fnp-2971	274	85	pigmented	pigmented	ADJ
fnp-2971	274	86	glia	glia	NOUN
fnp-2971	274	87	.	.	PUNCT
fnp-2971	275	1	jama	jama	PROPN
fnp-2971	275	2	neurol	neurol	PROPN
fnp-2971	275	3	2016:73;1433	2016:73;1433	NUM
fnp-2971	275	4	-	-	SYM
fnp-2971	275	5	9	9	NUM
fnp-2971	275	6	.	.	NOUN
fnp-2971	275	7	15	15	NUM
fnp-2971	275	8	.	.	PUNCT
fnp-2971	276	1	elmore	elmore	NOUN
fnp-2971	276	2	mr	mr	PROPN
fnp-2971	276	3	,	,	PUNCT
fnp-2971	276	4	najafi	najafi	PROPN
fnp-2971	276	5	ar	ar	PROPN
fnp-2971	276	6	,	,	PUNCT
fnp-2971	276	7	koike	koike	PROPN
fnp-2971	276	8	ma	ma	PROPN
fnp-2971	276	9	,	,	PUNCT
fnp-2971	276	10	dagher	dagher	PROPN
fnp-2971	276	11	nn	nn	PROPN
fnp-2971	276	12	,	,	PUNCT
fnp-2971	276	13	spangenberg	spangenberg	PROPN
fnp-2971	276	14	ee	ee	PROPN
fnp-2971	276	15	,	,	PUNCT
fnp-2971	276	16	rice	rice	PROPN
fnp-2971	276	17	ra	ra	PROPN
fnp-2971	276	18	,	,	PUNCT
fnp-2971	276	19	kitazawa	kitazawa	PROPN
fnp-2971	276	20	m	m	PROPN
fnp-2971	276	21	,	,	PUNCT
fnp-2971	276	22	matusow	matusow	PROPN
fnp-2971	276	23	b	b	PROPN
fnp-2971	276	24	,	,	PUNCT
fnp-2971	276	25	nguyen	nguyen	PROPN
fnp-2971	276	26	h	h	PROPN
fnp-2971	276	27	,	,	PUNCT
fnp-2971	276	28	west	west	PROPN
fnp-2971	276	29	bl	bl	PROPN
fnp-2971	276	30	,	,	PUNCT
fnp-2971	276	31	green	green	PROPN
fnp-2971	276	32	kn	kn	PROPN
fnp-2971	276	33	.	.	PUNCT
fnp-2971	276	34	colony	colony	NOUN
fnp-2971	276	35	-	-	PUNCT
fnp-2971	276	36	stimulating	stimulate	VERB
fnp-2971	276	37	factor	factor	NOUN
fnp-2971	276	38	1	1	NUM
fnp-2971	276	39	receptor	receptor	NOUN
fnp-2971	276	40	signaling	signal	VERB
fnp-2971	276	41	is	be	AUX
fnp-2971	276	42	necessary	necessary	ADJ
fnp-2971	276	43	for	for	ADP
fnp-2971	276	44	microglia	microglia	ADJ
fnp-2971	276	45	viability	viability	NOUN
fnp-2971	276	46	,	,	PUNCT
fnp-2971	276	47	unmasking	unmask	VERB
fnp-2971	276	48	a	a	DET
fnp-2971	276	49	microglia	microglia	ADJ
fnp-2971	276	50	progenitor	progenitor	NOUN
fnp-2971	276	51	cell	cell	NOUN
fnp-2971	276	52	in	in	ADP
fnp-2971	276	53	the	the	DET
fnp-2971	276	54	adult	adult	NOUN
fnp-2971	276	55	brain	brain	NOUN
fnp-2971	276	56	.	.	PUNCT
fnp-2971	276	57	neuron	neuron	PROPN
fnp-2971	277	1	2014:82;380	2014:82;380	PROPN
fnp-2971	277	2	-	-	SYM
fnp-2971	277	3	97	97	NUM
fnp-2971	277	4	.	.	PUNCT
fnp-2971	277	5	16	16	NUM
fnp-2971	277	6	.	.	PUNCT
fnp-2971	278	1	pridans	pridan	NOUN
fnp-2971	278	2	c	c	X
fnp-2971	278	3	,	,	PUNCT
fnp-2971	278	4	sauter	sauter	PROPN
fnp-2971	278	5	ka	ka	PROPN
fnp-2971	278	6	,	,	PUNCT
fnp-2971	278	7	baer	baer	PROPN
fnp-2971	278	8	k	k	PROPN
fnp-2971	278	9	,	,	PUNCT
fnp-2971	278	10	kissel	kissel	PROPN
fnp-2971	278	11	h	h	PROPN
fnp-2971	278	12	,	,	PUNCT
fnp-2971	278	13	hume	hume	PROPN
fnp-2971	278	14	da	da	PROPN
fnp-2971	278	15	.	.	PUNCT
fnp-2971	279	1	csf1r	csf1r	PROPN
fnp-2971	279	2	mutations	mutation	NOUN
fnp-2971	279	3	in	in	ADP
fnp-2971	279	4	hereditary	hereditary	ADJ
fnp-2971	279	5	diffuse	diffuse	NOUN
fnp-2971	279	6	leukoencephalopathy	leukoencephalopathy	ADJ
fnp-2971	279	7	with	with	ADP
fnp-2971	279	8	spheroids	spheroid	NOUN
fnp-2971	279	9	are	be	AUX
fnp-2971	279	10	loss	loss	NOUN
fnp-2971	279	11	of	of	ADP
fnp-2971	279	12	function	function	NOUN
fnp-2971	279	13	.	.	PUNCT
fnp-2971	280	1	sci	sci	PROPN
fnp-2971	280	2	rep	rep	PROPN
fnp-2971	280	3	2013:3;3013	2013:3;3013	PROPN
fnp-2971	280	4	.	.	PROPN
fnp-2971	281	1	17	17	NUM
fnp-2971	281	2	.	.	PUNCT
fnp-2971	281	3	konno	konno	PROPN
fnp-2971	281	4	t	t	PROPN
fnp-2971	281	5	,	,	PUNCT
fnp-2971	281	6	tada	tada	PROPN
fnp-2971	281	7	m	m	PROPN
fnp-2971	281	8	,	,	PUNCT
fnp-2971	281	9	tada	tada	PROPN
fnp-2971	281	10	m	m	PROPN
fnp-2971	281	11	,	,	PUNCT
fnp-2971	281	12	koyama	koyama	PROPN
fnp-2971	281	13	a	a	PRON
fnp-2971	281	14	,	,	PUNCT
fnp-2971	281	15	nozaki	nozaki	NOUN
fnp-2971	281	16	h	h	NOUN
fnp-2971	281	17	,	,	PUNCT
fnp-2971	281	18	harigaya	harigaya	PROPN
fnp-2971	281	19	y	y	PROPN
fnp-2971	281	20	,	,	PUNCT
fnp-2971	281	21	nishimiya	nishimiya	PROPN
fnp-2971	281	22	j	j	PROPN
fnp-2971	281	23	,	,	PUNCT
fnp-2971	281	24	matsunaga	matsunaga	NOUN
fnp-2971	281	25	a	a	PRON
fnp-2971	281	26	,	,	PUNCT
fnp-2971	281	27	yoshikura	yoshikura	NOUN
fnp-2971	281	28	n	n	NOUN
fnp-2971	281	29	,	,	PUNCT
fnp-2971	281	30	ishihara	ishihara	PROPN
fnp-2971	281	31	k	k	PROPN
fnp-2971	281	32	,	,	PUNCT
fnp-2971	281	33	arakawa	arakawa	PROPN
fnp-2971	281	34	m	m	PROPN
fnp-2971	281	35	,	,	PUNCT
fnp-2971	281	36	isami	isami	VERB
fnp-2971	281	37	a	a	PRON
fnp-2971	281	38	,	,	PUNCT
fnp-2971	281	39	okazaki	okazaki	PROPN
fnp-2971	281	40	k	k	PROPN
fnp-2971	281	41	,	,	PUNCT
fnp-2971	281	42	yokoo	yokoo	PROPN
fnp-2971	281	43	h	h	PROPN
fnp-2971	281	44	,	,	PUNCT
fnp-2971	281	45	itoh	itoh	PROPN
fnp-2971	281	46	k	k	PROPN
fnp-2971	281	47	,	,	PUNCT
fnp-2971	281	48	yoneda	yoneda	PROPN
fnp-2971	281	49	m	m	PROPN
fnp-2971	281	50	,	,	PUNCT
fnp-2971	281	51	kawamura	kawamura	PROPN
fnp-2971	281	52	m	m	PROPN
fnp-2971	281	53	,	,	PUNCT
fnp-2971	281	54	inuzuka	inuzuka	PROPN
fnp-2971	281	55	t	t	PROPN
fnp-2971	281	56	,	,	PUNCT
fnp-2971	281	57	takahashi	takahashi	PROPN
fnp-2971	281	58	h	h	PROPN
fnp-2971	281	59	,	,	PUNCT
fnp-2971	281	60	nishizawa	nishizawa	PROPN
fnp-2971	281	61	m	m	PROPN
fnp-2971	281	62	,	,	PUNCT
fnp-2971	281	63	onodera	onodera	NOUN
fnp-2971	281	64	o	o	NOUN
fnp-2971	281	65	,	,	PUNCT
fnp-2971	281	66	kakita	kakita	PROPN
fnp-2971	281	67	a	a	X
fnp-2971	281	68	,	,	PUNCT
fnp-2971	281	69	ikeuchi	ikeuchi	ADJ
fnp-2971	281	70	t.	t.	PROPN
fnp-2971	281	71	haploinsufficiency	haploinsufficiency	NOUN
fnp-2971	281	72	of	of	ADP
fnp-2971	281	73	csf-1r	csf-1r	NOUN
fnp-2971	281	74	and	and	CCONJ
fnp-2971	281	75	clinicopathologic	clinicopathologic	ADJ
fnp-2971	281	76	characterization	characterization	NOUN
fnp-2971	281	77	in	in	ADP
fnp-2971	281	78	patients	patient	NOUN
fnp-2971	281	79	with	with	ADP
fnp-2971	281	80	hdls	hdls	PROPN
fnp-2971	281	81	.	.	PUNCT
fnp-2971	282	1	neurology	neurology	NOUN
fnp-2971	282	2	2014:82;139	2014:82;139	NUM
fnp-2971	282	3	-	-	SYM
fnp-2971	282	4	48	48	NUM
fnp-2971	282	5	.	.	PUNCT
fnp-2971	282	6	18	18	NUM
fnp-2971	282	7	.	.	PUNCT
fnp-2971	283	1	hume	hume	PROPN
fnp-2971	283	2	da	da	PROPN
fnp-2971	283	3	,	,	PUNCT
fnp-2971	283	4	caruso	caruso	PROPN
fnp-2971	283	5	m	m	PROPN
fnp-2971	283	6	,	,	PUNCT
fnp-2971	283	7	ferrari	ferrari	PROPN
fnp-2971	283	8	-	-	PUNCT
fnp-2971	283	9	cestari	cestari	PROPN
fnp-2971	283	10	m	m	PROPN
fnp-2971	283	11	,	,	PUNCT
fnp-2971	283	12	summers	summer	NOUN
fnp-2971	283	13	km	km	PROPN
fnp-2971	283	14	,	,	PUNCT
fnp-2971	283	15	pridans	pridan	NOUN
fnp-2971	283	16	c	c	PROPN
fnp-2971	283	17	,	,	PUNCT
fnp-2971	283	18	irvine	irvine	PROPN
fnp-2971	283	19	km	km	PROPN
fnp-2971	283	20	.	.	PUNCT
fnp-2971	284	1	phenotypic	phenotypic	ADJ
fnp-2971	284	2	impacts	impact	NOUN
fnp-2971	284	3	of	of	ADP
fnp-2971	284	4	csf1r	csf1r	PROPN
fnp-2971	284	5	deficiencies	deficiency	NOUN
fnp-2971	284	6	in	in	ADP
fnp-2971	284	7	humans	human	NOUN
fnp-2971	284	8	and	and	CCONJ
fnp-2971	284	9	model	model	NOUN
fnp-2971	284	10	organisms	organism	NOUN
fnp-2971	284	11	.	.	PUNCT
fnp-2971	285	1	j	j	PROPN
fnp-2971	285	2	leukoc	leukoc	VERB
fnp-2971	285	3	biol	biol	PROPN
fnp-2971	285	4	2019	2019	NUM
fnp-2971	285	5	.	.	PUNCT
fnp-2971	286	1	19	19	NUM
fnp-2971	286	2	.	.	NOUN
fnp-2971	286	3	oosterhof	oosterhof	PROPN
fnp-2971	286	4	n	n	CCONJ
fnp-2971	286	5	,	,	PUNCT
fnp-2971	286	6	chang	chang	PROPN
fnp-2971	286	7	ij	ij	PROPN
fnp-2971	286	8	,	,	PUNCT
fnp-2971	286	9	karimiani	karimiani	PROPN
fnp-2971	286	10	eg	eg	PROPN
fnp-2971	286	11	,	,	PUNCT
fnp-2971	286	12	kuil	kuil	PROPN
fnp-2971	286	13	le	le	PROPN
fnp-2971	286	14	,	,	PUNCT
fnp-2971	286	15	jensen	jensen	PROPN
fnp-2971	286	16	dm	dm	PROPN
fnp-2971	286	17	,	,	PUNCT
fnp-2971	286	18	daza	daza	PROPN
fnp-2971	286	19	r	r	PROPN
fnp-2971	286	20	,	,	PUNCT
fnp-2971	286	21	young	young	ADJ
fnp-2971	286	22	e	e	NOUN
fnp-2971	286	23	,	,	PUNCT
fnp-2971	286	24	astle	astle	PROPN
fnp-2971	286	25	l	l	PROPN
fnp-2971	286	26	,	,	PUNCT
fnp-2971	286	27	van	van	PROPN
fnp-2971	286	28	der	der	NOUN
fnp-2971	286	29	linde	linde	PROPN
fnp-2971	286	30	hc	hc	PROPN
fnp-2971	286	31	,	,	PUNCT
fnp-2971	286	32	shivaram	shivaram	PROPN
fnp-2971	286	33	gm	gm	PROPN
fnp-2971	286	34	,	,	PUNCT
fnp-2971	286	35	demmers	demmer	VERB
fnp-2971	286	36	j	j	PROPN
fnp-2971	286	37	,	,	PUNCT
fnp-2971	286	38	latimer	latimer	PROPN
fnp-2971	286	39	cs	cs	PROPN
fnp-2971	286	40	,	,	PUNCT
fnp-2971	286	41	keene	keene	PROPN
fnp-2971	286	42	cd	cd	PROPN
fnp-2971	286	43	,	,	PUNCT
fnp-2971	286	44	loter	lot	ADJ
fnp-2971	286	45	e	e	NOUN
fnp-2971	286	46	,	,	PUNCT
fnp-2971	286	47	maroofian	maroofian	ADJ
fnp-2971	286	48	r	r	NOUN
fnp-2971	286	49	,	,	PUNCT
fnp-2971	286	50	van	van	PROPN
fnp-2971	286	51	ham	ham	PROPN
fnp-2971	286	52	tj	tj	PROPN
fnp-2971	286	53	,	,	PUNCT
fnp-2971	286	54	hevner	hevner	NOUN
fnp-2971	286	55	rf	rf	NOUN
fnp-2971	286	56	,	,	PUNCT
fnp-2971	286	57	bennett	bennett	PROPN
fnp-2971	286	58	jt	jt	PROPN
fnp-2971	286	59	.	.	PUNCT
fnp-2971	287	1	homozygous	homozygous	ADJ
fnp-2971	287	2	mutations	mutation	NOUN
fnp-2971	287	3	in	in	ADP
fnp-2971	287	4	csf1r	csf1r	PROPN
fnp-2971	287	5	cause	cause	VERB
fnp-2971	287	6	a	a	DET
fnp-2971	287	7	pediatric	pediatric	ADJ
fnp-2971	287	8	-	-	PUNCT
fnp-2971	287	9	onset	onset	NOUN
fnp-2971	287	10	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	287	11	and	and	CCONJ
fnp-2971	287	12	can	can	AUX
fnp-2971	287	13	result	result	VERB
fnp-2971	287	14	in	in	ADP
fnp-2971	287	15	congenital	congenital	ADJ
fnp-2971	287	16	absence	absence	NOUN
fnp-2971	287	17	of	of	ADP
fnp-2971	287	18	microglia	microglia	NOUN
fnp-2971	287	19	.	.	PUNCT
fnp-2971	287	20	am	be	AUX
fnp-2971	287	21	j	j	PROPN
fnp-2971	287	22	hum	hum	PROPN
fnp-2971	287	23	genet	genet	PROPN
fnp-2971	287	24	2019:104;936	2019:104;936	NUM
fnp-2971	287	25	-	-	SYM
fnp-2971	287	26	47	47	NUM
fnp-2971	287	27	.	.	PUNCT
fnp-2971	288	1	20	20	NUM
fnp-2971	288	2	.	.	PUNCT
fnp-2971	289	1	graeber	graeber	PROPN
fnp-2971	289	2	mb	mb	PROPN
fnp-2971	289	3	,	,	PUNCT
fnp-2971	289	4	streit	streit	PROPN
fnp-2971	289	5	wj	wj	PROPN
fnp-2971	289	6	.	.	PUNCT
fnp-2971	290	1	microglia	microglia	ADJ
fnp-2971	290	2	:	:	PUNCT
fnp-2971	290	3	biology	biology	NOUN
fnp-2971	290	4	and	and	CCONJ
fnp-2971	290	5	pathology	pathology	NOUN
fnp-2971	290	6	.	.	PUNCT
fnp-2971	291	1	acta	acta	PROPN
fnp-2971	291	2	neuropathol	neuropathol	PROPN
fnp-2971	292	1	2010:119;89	2010:119;89	PROPN
fnp-2971	292	2	-	-	SYM
fnp-2971	292	3	105	105	NUM
fnp-2971	292	4	.	.	PUNCT
fnp-2971	293	1	21	21	NUM
fnp-2971	293	2	.	.	PUNCT
fnp-2971	294	1	berezovskaya	berezovskaya	PROPN
fnp-2971	294	2	o	o	NOUN
fnp-2971	294	3	,	,	PUNCT
fnp-2971	294	4	maysinger	maysinger	PROPN
fnp-2971	294	5	d	d	NOUN
fnp-2971	294	6	,	,	PUNCT
fnp-2971	294	7	fedoroff	fedoroff	PROPN
fnp-2971	294	8	s.	s.	PROPN
fnp-2971	294	9	colony	colony	PROPN
fnp-2971	294	10	stimulating	stimulate	VERB
fnp-2971	294	11	factor-1	factor-1	NUM
fnp-2971	294	12	potentiates	potentiate	VERB
fnp-2971	294	13	neuronal	neuronal	ADJ
fnp-2971	294	14	survival	survival	NOUN
fnp-2971	294	15	in	in	ADP
fnp-2971	294	16	cerebral	cerebral	ADJ
fnp-2971	294	17	cortex	cortex	NOUN
fnp-2971	294	18	ischemic	ischemic	ADJ
fnp-2971	294	19	lesion	lesion	NOUN
fnp-2971	294	20	.	.	PUNCT
fnp-2971	295	1	acta	acta	PROPN
fnp-2971	295	2	neuropathol	neuropathol	PROPN
fnp-2971	295	3	1996:92;479	1996:92;479	PROPN
fnp-2971	295	4	-	-	SYM
fnp-2971	295	5	86	86	NUM
fnp-2971	295	6	.	.	PUNCT
fnp-2971	296	1	22	22	NUM
fnp-2971	296	2	.	.	PUNCT
fnp-2971	297	1	fedoroff	fedoroff	PROPN
fnp-2971	297	2	s	s	PROPN
fnp-2971	297	3	,	,	PUNCT
fnp-2971	297	4	berezovskaya	berezovskaya	NOUN
fnp-2971	297	5	o	o	NOUN
fnp-2971	297	6	,	,	PUNCT
fnp-2971	297	7	maysinger	maysinger	PROPN
fnp-2971	297	8	d.	d.	PROPN
fnp-2971	297	9	role	role	NOUN
fnp-2971	297	10	of	of	ADP
fnp-2971	297	11	colony	colony	NOUN
fnp-2971	297	12	stimulating	stimulate	VERB
fnp-2971	297	13	factor-1	factor-1	PROPN
fnp-2971	297	14	in	in	ADP
fnp-2971	297	15	brain	brain	NOUN
fnp-2971	297	16	damage	damage	NOUN
fnp-2971	297	17	caused	cause	VERB
fnp-2971	297	18	by	by	ADP
fnp-2971	297	19	ischemia	ischemia	NOUN
fnp-2971	297	20	.	.	PUNCT
fnp-2971	298	1	neurosci	neurosci	PROPN
fnp-2971	298	2	biobehav	biobehav	PROPN
fnp-2971	298	3	rev	rev	VERB
fnp-2971	298	4	1997:21;187	1997:21;187	NUM
fnp-2971	298	5	-	-	SYM
fnp-2971	298	6	91	91	NUM
fnp-2971	298	7	.	.	PUNCT
fnp-2971	299	1	23	23	NUM
fnp-2971	299	2	.	.	PUNCT
fnp-2971	300	1	szalay	szalay	NOUN
fnp-2971	300	2	g	g	NOUN
fnp-2971	300	3	,	,	PUNCT
fnp-2971	300	4	martinecz	martinecz	PROPN
fnp-2971	300	5	b	b	NOUN
fnp-2971	300	6	,	,	PUNCT
fnp-2971	300	7	lenart	lenart	ADJ
fnp-2971	300	8	n	n	CCONJ
fnp-2971	300	9	,	,	PUNCT
fnp-2971	300	10	kornyei	kornyei	PROPN
fnp-2971	300	11	z	z	PROPN
fnp-2971	300	12	,	,	PUNCT
fnp-2971	300	13	orsolits	orsolit	NOUN
fnp-2971	300	14	b	b	PROPN
fnp-2971	300	15	,	,	PUNCT
fnp-2971	300	16	judak	judak	PROPN
fnp-2971	300	17	l	l	PROPN
fnp-2971	300	18	,	,	PUNCT
fnp-2971	300	19	csaszar	csaszar	VERB
fnp-2971	300	20	e	e	NOUN
fnp-2971	300	21	,	,	PUNCT
fnp-2971	300	22	fekete	fekete	PROPN
fnp-2971	300	23	r	r	PROPN
fnp-2971	300	24	,	,	PUNCT
fnp-2971	300	25	west	west	PROPN
fnp-2971	300	26	bl	bl	PROPN
fnp-2971	300	27	,	,	PUNCT
fnp-2971	300	28	katona	katona	PROPN
fnp-2971	300	29	g	g	PROPN
fnp-2971	300	30	,	,	PUNCT
fnp-2971	300	31	rozsa	rozsa	NOUN
fnp-2971	300	32	b	b	PROPN
fnp-2971	300	33	,	,	PUNCT
fnp-2971	300	34	denes	dene	VERB
fnp-2971	300	35	a.	a.	NOUN
fnp-2971	300	36	microglia	microglia	ADJ
fnp-2971	300	37	protect	protect	NOUN
fnp-2971	300	38	against	against	ADP
fnp-2971	300	39	brain	brain	NOUN
fnp-2971	300	40	injury	injury	NOUN
fnp-2971	300	41	and	and	CCONJ
fnp-2971	300	42	their	their	PRON
fnp-2971	300	43	selective	selective	ADJ
fnp-2971	300	44	elimination	elimination	NOUN
fnp-2971	300	45	dysregulates	dysregulate	VERB
fnp-2971	300	46	neuronal	neuronal	ADJ
fnp-2971	300	47	network	network	NOUN
fnp-2971	300	48	activity	activity	NOUN
fnp-2971	300	49	after	after	ADP
fnp-2971	300	50	stroke	stroke	NOUN
fnp-2971	300	51	.	.	PUNCT
fnp-2971	301	1	nat	nat	PROPN
fnp-2971	301	2	commun	commun	PROPN
fnp-2971	301	3	2016:7;11499	2016:7;11499	NUM
fnp-2971	301	4	.	.	PUNCT
fnp-2971	302	1	24	24	NUM
fnp-2971	302	2	.	.	PUNCT
fnp-2971	302	3	erblich	erblich	PROPN
fnp-2971	302	4	b	b	PROPN
fnp-2971	302	5	,	,	PUNCT
fnp-2971	302	6	zhu	zhu	PROPN
fnp-2971	302	7	l	l	NOUN
fnp-2971	302	8	,	,	PUNCT
fnp-2971	302	9	etgen	etgen	PROPN
fnp-2971	302	10	am	am	PROPN
fnp-2971	302	11	,	,	PUNCT
fnp-2971	302	12	dobrenis	dobrenis	PROPN
fnp-2971	302	13	k	k	PROPN
fnp-2971	302	14	,	,	PUNCT
fnp-2971	302	15	pollard	pollard	PROPN
fnp-2971	302	16	jw	jw	PROPN
fnp-2971	302	17	.	.	PROPN
fnp-2971	302	18	absence	absence	NOUN
fnp-2971	302	19	of	of	ADP
fnp-2971	302	20	colony	colony	NOUN
fnp-2971	302	21	stimulation	stimulation	NOUN
fnp-2971	302	22	factor-1	factor-1	NOUN
fnp-2971	302	23	receptor	receptor	NOUN
fnp-2971	302	24	results	result	NOUN
fnp-2971	302	25	in	in	ADP
fnp-2971	302	26	loss	loss	NOUN
fnp-2971	302	27	of	of	ADP
fnp-2971	302	28	microglia	microglia	NOUN
fnp-2971	302	29	,	,	PUNCT
fnp-2971	302	30	disrupted	disrupt	VERB
fnp-2971	302	31	brain	brain	NOUN
fnp-2971	302	32	development	development	NOUN
fnp-2971	302	33	and	and	CCONJ
fnp-2971	302	34	olfactory	olfactory	ADJ
fnp-2971	302	35	deficits	deficit	NOUN
fnp-2971	302	36	.	.	PUNCT
fnp-2971	303	1	plos	plos	PROPN
fnp-2971	303	2	one	one	NUM
fnp-2971	303	3	2011:6;e26317	2011:6;e26317	NUM
fnp-2971	303	4	.	.	PUNCT
fnp-2971	304	1	25	25	NUM
fnp-2971	304	2	.	.	PUNCT
fnp-2971	305	1	lassmann	lassmann	PROPN
fnp-2971	305	2	h.	h.	PROPN
fnp-2971	305	3	mechanisms	mechanism	NOUN
fnp-2971	305	4	of	of	ADP
fnp-2971	305	5	white	white	ADJ
fnp-2971	305	6	matter	matter	NOUN
fnp-2971	305	7	damage	damage	NOUN
fnp-2971	305	8	in	in	ADP
fnp-2971	305	9	multiple	multiple	ADJ
fnp-2971	305	10	sclerosis	sclerosis	NOUN
fnp-2971	305	11	.	.	PUNCT
fnp-2971	306	1	glia	glia	PROPN
fnp-2971	306	2	2014:62;1816	2014:62;1816	PROPN
fnp-2971	306	3	-	-	SYM
fnp-2971	306	4	30	30	NUM
fnp-2971	306	5	.	.	PUNCT
fnp-2971	306	6	26	26	NUM
fnp-2971	306	7	.	.	PUNCT
fnp-2971	307	1	ramlackhansingh	ramlackhansingh	PROPN
fnp-2971	307	2	af	af	PROPN
fnp-2971	307	3	,	,	PUNCT
fnp-2971	307	4	brooks	brooks	PROPN
fnp-2971	307	5	dj	dj	PROPN
fnp-2971	307	6	,	,	PUNCT
fnp-2971	307	7	greenwood	greenwood	PROPN
fnp-2971	307	8	rj	rj	PROPN
fnp-2971	307	9	,	,	PUNCT
fnp-2971	307	10	bose	bose	PROPN
fnp-2971	307	11	sk	sk	PROPN
fnp-2971	307	12	,	,	PUNCT
fnp-2971	307	13	turkheimer	turkheimer	NOUN
fnp-2971	307	14	fe	fe	PROPN
fnp-2971	307	15	,	,	PUNCT
fnp-2971	307	16	kinnunen	kinnunen	PROPN
fnp-2971	307	17	km	km	PROPN
fnp-2971	307	18	,	,	PUNCT
fnp-2971	307	19	gentleman	gentleman	NOUN
fnp-2971	307	20	s	s	PROPN
fnp-2971	307	21	,	,	PUNCT
fnp-2971	307	22	heckemann	heckemann	PROPN
fnp-2971	307	23	ra	ra	PROPN
fnp-2971	307	24	,	,	PUNCT
fnp-2971	307	25	gunanayagam	gunanayagam	PROPN
fnp-2971	307	26	k	k	NOUN
fnp-2971	307	27	,	,	PUNCT
fnp-2971	307	28	gelosa	gelosa	PROPN
fnp-2971	307	29	g	g	PROPN
fnp-2971	307	30	,	,	PUNCT
fnp-2971	307	31	sharp	sharp	ADJ
fnp-2971	307	32	dj	dj	NOUN
fnp-2971	307	33	.	.	PUNCT
fnp-2971	308	1	inflammation	inflammation	NOUN
fnp-2971	308	2	after	after	ADP
fnp-2971	308	3	trauma	trauma	NOUN
fnp-2971	308	4	:	:	PUNCT
fnp-2971	308	5	microglial	microglial	ADJ
fnp-2971	308	6	activation	activation	NOUN
fnp-2971	308	7	and	and	CCONJ
fnp-2971	308	8	traumatic	traumatic	ADJ
fnp-2971	308	9	brain	brain	NOUN
fnp-2971	308	10	injury	injury	NOUN
fnp-2971	308	11	.	.	PUNCT
fnp-2971	309	1	ann	ann	PROPN
fnp-2971	309	2	neurol	neurol	PROPN
fnp-2971	309	3	2011:70;374	2011:70;374	PROPN
fnp-2971	309	4	-	-	SYM
fnp-2971	309	5	83	83	NUM
fnp-2971	309	6	.	.	PUNCT
fnp-2971	309	7	27	27	NUM
fnp-2971	309	8	.	.	PUNCT
fnp-2971	310	1	cherry	cherry	PROPN
fnp-2971	310	2	jd	jd	PROPN
fnp-2971	310	3	,	,	PUNCT
fnp-2971	310	4	tripodis	tripodis	PROPN
fnp-2971	310	5	y	y	PROPN
fnp-2971	310	6	,	,	PUNCT
fnp-2971	310	7	alvarez	alvarez	PROPN
fnp-2971	310	8	ve	ve	PROPN
fnp-2971	310	9	,	,	PUNCT
fnp-2971	310	10	huber	huber	PROPN
fnp-2971	310	11	b	b	PROPN
fnp-2971	310	12	,	,	PUNCT
fnp-2971	310	13	kiernan	kiernan	PROPN
fnp-2971	310	14	pt	pt	PROPN
fnp-2971	310	15	,	,	PUNCT
fnp-2971	310	16	daneshvar	daneshvar	NOUN
fnp-2971	310	17	dh	dh	NOUN
fnp-2971	310	18	,	,	PUNCT
fnp-2971	310	19	mez	mez	PROPN
fnp-2971	310	20	j	j	PROPN
fnp-2971	310	21	,	,	PUNCT
fnp-2971	310	22	montenigro	montenigro	ADJ
fnp-2971	310	23	ph	ph	PROPN
fnp-2971	310	24	,	,	PUNCT
fnp-2971	310	25	solomon	solomon	PROPN
fnp-2971	310	26	tm	tm	PROPN
fnp-2971	310	27	,	,	PUNCT
fnp-2971	310	28	alosco	alosco	PROPN
fnp-2971	310	29	ml	ml	PROPN
fnp-2971	310	30	,	,	PUNCT
fnp-2971	310	31	stern	stern	PROPN
fnp-2971	310	32	ra	ra	PROPN
fnp-2971	310	33	,	,	PUNCT
fnp-2971	310	34	mckee	mckee	PROPN
fnp-2971	310	35	ac	ac	PROPN
fnp-2971	310	36	,	,	PUNCT
fnp-2971	310	37	stein	stein	PROPN
fnp-2971	310	38	td	td	PROPN
fnp-2971	310	39	.	.	PUNCT
fnp-2971	311	1	microglial	microglial	ADJ
fnp-2971	311	2	neuroinflammation	neuroinflammation	NOUN
fnp-2971	311	3	contributes	contribute	VERB
fnp-2971	311	4	to	to	ADP
fnp-2971	311	5	tau	tau	PROPN
fnp-2971	311	6	accumulation	accumulation	NOUN
fnp-2971	311	7	in	in	ADP
fnp-2971	311	8	chronic	chronic	ADJ
fnp-2971	311	9	traumatic	traumatic	ADJ
fnp-2971	311	10	encephalopathy	encephalopathy	NOUN
fnp-2971	311	11	.	.	PUNCT
fnp-2971	312	1	acta	acta	PROPN
fnp-2971	312	2	neuropathol	neuropathol	PROPN
fnp-2971	312	3	commun	commun	PROPN
fnp-2971	312	4	2016:4;112	2016:4;112	PROPN
fnp-2971	312	5	.	.	PUNCT
fnp-2971	313	1	28	28	NUM
fnp-2971	313	2	.	.	PUNCT
fnp-2971	313	3	lafrenaye	lafrenaye	VERB
fnp-2971	313	4	ad	ad	NOUN
fnp-2971	313	5	,	,	PUNCT
fnp-2971	313	6	todani	todani	PROPN
fnp-2971	313	7	m	m	PROPN
fnp-2971	313	8	,	,	PUNCT
fnp-2971	313	9	walker	walker	PROPN
fnp-2971	313	10	sa	sa	PROPN
fnp-2971	313	11	,	,	PUNCT
fnp-2971	313	12	povlishock	povlishock	PROPN
fnp-2971	313	13	jt	jt	PROPN
fnp-2971	313	14	.	.	PUNCT
fnp-2971	314	1	microglia	microglia	ADJ
fnp-2971	314	2	processes	process	NOUN
fnp-2971	314	3	associate	associate	ADJ
fnp-2971	314	4	with	with	ADP
fnp-2971	314	5	diffusely	diffusely	ADV
fnp-2971	314	6	injured	injure	VERB
fnp-2971	314	7	axons	axon	NOUN
fnp-2971	314	8	following	follow	VERB
fnp-2971	314	9	mild	mild	ADJ
fnp-2971	314	10	traumatic	traumatic	ADJ
fnp-2971	314	11	brain	brain	NOUN
fnp-2971	314	12	injury	injury	NOUN
fnp-2971	314	13	in	in	ADP
fnp-2971	314	14	the	the	DET
fnp-2971	314	15	micro	micro	PROPN
fnp-2971	314	16	pig	pig	PROPN
fnp-2971	314	17	.	.	PUNCT
fnp-2971	315	1	j	j	PROPN
fnp-2971	315	2	neuroinflammation	neuroinflammation	PROPN
fnp-2971	315	3	2015:12;186	2015:12;186	PROPN
fnp-2971	315	4	.	.	PUNCT
fnp-2971	316	1	29	29	NUM
fnp-2971	316	2	.	.	PUNCT
fnp-2971	316	3	lafrenaye	lafrenaye	VERB
fnp-2971	316	4	ad	ad	NOUN
fnp-2971	316	5	.	.	PUNCT
fnp-2971	317	1	physical	physical	ADJ
fnp-2971	317	2	interactions	interaction	NOUN
fnp-2971	317	3	between	between	ADP
fnp-2971	317	4	activated	activate	VERB
fnp-2971	317	5	microglia	microglia	NOUN
fnp-2971	317	6	and	and	CCONJ
fnp-2971	317	7	injured	injured	ADJ
fnp-2971	317	8	axons	axon	NOUN
fnp-2971	317	9	:	:	PUNCT
fnp-2971	317	10	do	do	AUX
fnp-2971	317	11	all	all	DET
fnp-2971	317	12	contacts	contact	NOUN
fnp-2971	317	13	lead	lead	VERB
fnp-2971	317	14	to	to	PART
fnp-2971	317	15	phagocytosis	phagocytosis	VERB
fnp-2971	317	16	?	?	PUNCT
fnp-2971	318	1	neural	neural	ADJ
fnp-2971	318	2	regen	regen	PROPN
fnp-2971	318	3	res	res	PROPN
fnp-2971	318	4	2016:11;538	2016:11;538	NUM
fnp-2971	318	5	-	-	SYM
fnp-2971	318	6	40	40	NUM
fnp-2971	318	7	.	.	PUNCT
fnp-2971	318	8	30	30	NUM
fnp-2971	318	9	.	.	PUNCT
fnp-2971	319	1	singh	singh	PROPN
fnp-2971	319	2	s	s	PROPN
fnp-2971	319	3	,	,	PUNCT
fnp-2971	319	4	metz	metz	PROPN
fnp-2971	319	5	i	i	PROPN
fnp-2971	319	6	,	,	PUNCT
fnp-2971	319	7	amor	amor	PROPN
fnp-2971	319	8	s	s	PROPN
fnp-2971	319	9	,	,	PUNCT
fnp-2971	319	10	van	van	PROPN
fnp-2971	319	11	der	der	PROPN
fnp-2971	319	12	valk	valk	PROPN
fnp-2971	319	13	p	p	NOUN
fnp-2971	319	14	,	,	PUNCT
fnp-2971	319	15	stadelmann	stadelmann	PROPN
fnp-2971	319	16	c	c	AUX
fnp-2971	319	17	,	,	PUNCT
fnp-2971	319	18	bruck	bruck	PROPN
fnp-2971	319	19	w.	w.	PROPN
fnp-2971	319	20	microglial	microglial	ADJ
fnp-2971	319	21	nodules	nodule	NOUN
fnp-2971	319	22	in	in	ADP
fnp-2971	319	23	early	early	ADJ
fnp-2971	319	24	multiple	multiple	ADJ
fnp-2971	319	25	sclerosis	sclerosis	NOUN
fnp-2971	319	26	white	white	ADJ
fnp-2971	319	27	matter	matter	NOUN
fnp-2971	319	28	are	be	AUX
fnp-2971	319	29	associated	associate	VERB
fnp-2971	319	30	with	with	ADP
fnp-2971	319	31	degenerating	degenerate	VERB
fnp-2971	319	32	axons	axon	NOUN
fnp-2971	319	33	.	.	PUNCT
fnp-2971	320	1	acta	acta	PROPN
fnp-2971	320	2	neuropathol	neuropathol	PROPN
fnp-2971	320	3	2013:125;595	2013:125;595	PROPN
fnp-2971	320	4	-	-	SYM
fnp-2971	320	5	608	608	NUM
fnp-2971	320	6	.	.	PUNCT
fnp-2971	321	1	31	31	NUM
fnp-2971	321	2	.	.	PUNCT
fnp-2971	322	1	yamashita	yamashita	PROPN
fnp-2971	322	2	m	m	PROPN
fnp-2971	322	3	,	,	PUNCT
fnp-2971	322	4	yamamoto	yamamoto	PROPN
fnp-2971	322	5	t.	t.	PROPN
fnp-2971	322	6	neuroaxonal	neuroaxonal	PROPN
fnp-2971	322	7	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	322	8	with	with	ADP
fnp-2971	322	9	axonal	axonal	ADJ
fnp-2971	322	10	spheroids	spheroid	NOUN
fnp-2971	322	11	.	.	PUNCT
fnp-2971	323	1	eur	eur	PROPN
fnp-2971	323	2	neurol	neurol	PROPN
fnp-2971	323	3	2002:48;20	2002:48;20	NOUN
fnp-2971	323	4	-	-	SYM
fnp-2971	323	5	5	5	NUM
fnp-2971	323	6	.	.	NOUN
fnp-2971	323	7	32	32	NUM
fnp-2971	323	8	.	.	PUNCT
fnp-2971	324	1	freeman	freeman	PROPN
fnp-2971	324	2	sh	sh	PROPN
fnp-2971	324	3	,	,	PUNCT
fnp-2971	324	4	hyman	hyman	PROPN
fnp-2971	324	5	bt	bt	PROPN
fnp-2971	324	6	,	,	PUNCT
fnp-2971	324	7	sims	sims	PROPN
fnp-2971	324	8	kb	kb	PROPN
fnp-2971	324	9	,	,	PUNCT
fnp-2971	324	10	hedley	hedley	PROPN
fnp-2971	324	11	-	-	PUNCT
fnp-2971	324	12	whyte	whyte	PROPN
fnp-2971	324	13	et	et	PROPN
fnp-2971	324	14	,	,	PUNCT
fnp-2971	324	15	vossough	vossough	PROPN
fnp-2971	324	16	a	a	PRON
fnp-2971	324	17	,	,	PUNCT
fnp-2971	324	18	frosch	frosch	PROPN
fnp-2971	324	19	mp	mp	PROPN
fnp-2971	324	20	,	,	PUNCT
fnp-2971	324	21	schmahmann	schmahmann	PROPN
fnp-2971	324	22	jd	jd	PROPN
fnp-2971	324	23	.	.	PROPN
fnp-2971	324	24	adult	adult	NOUN
fnp-2971	324	25	onset	onset	NOUN
fnp-2971	324	26	leukodystrophy	leukodystrophy	NOUN
fnp-2971	324	27	with	with	ADP
fnp-2971	324	28	neuroaxonal	neuroaxonal	ADJ
fnp-2971	324	29	spheroids	spheroid	NOUN
fnp-2971	324	30	:	:	PUNCT
fnp-2971	324	31	clinical	clinical	ADJ
fnp-2971	324	32	,	,	PUNCT
fnp-2971	324	33	neuroimaging	neuroimaging	ADJ
fnp-2971	324	34	and	and	CCONJ
fnp-2971	324	35	neuropathologic	neuropathologic	ADJ
fnp-2971	324	36	observations	observation	NOUN
fnp-2971	324	37	.	.	PUNCT
fnp-2971	325	1	brain	brain	NOUN
fnp-2971	325	2	pathol	pathol	NOUN
fnp-2971	325	3	2009:19;39	2009:19;39	NOUN
fnp-2971	325	4	-	-	SYM
fnp-2971	325	5	47	47	NUM
fnp-2971	325	6	.	.	PUNCT
fnp-2971	326	1	33	33	NUM
fnp-2971	326	2	.	.	PUNCT
fnp-2971	327	1	ali	ali	PROPN
fnp-2971	327	2	zs	zs	PROPN
fnp-2971	327	3	,	,	PUNCT
fnp-2971	327	4	van	van	PROPN
fnp-2971	327	5	der	der	PROPN
fnp-2971	327	6	voorn	voorn	PROPN
fnp-2971	327	7	jp	jp	PROPN
fnp-2971	327	8	,	,	PUNCT
fnp-2971	327	9	powers	powers	PROPN
fnp-2971	327	10	jm	jm	PROPN
fnp-2971	327	11	.	.	PROPN
fnp-2971	328	1	a	a	DET
fnp-2971	328	2	comparative	comparative	ADJ
fnp-2971	328	3	morphologic	morphologic	ADJ
fnp-2971	328	4	analysis	analysis	NOUN
fnp-2971	328	5	of	of	ADP
fnp-2971	328	6	adult	adult	NOUN
fnp-2971	328	7	onset	onset	NOUN
fnp-2971	328	8	leukodystrophy	leukodystrophy	NOUN
fnp-2971	328	9	with	with	ADP
fnp-2971	328	10	neuroaxonal	neuroaxonal	ADJ
fnp-2971	328	11	spheroids	spheroid	NOUN
fnp-2971	328	12	and	and	CCONJ
fnp-2971	328	13	pigmented	pigmented	ADJ
fnp-2971	328	14	glia	glia	NOUN
fnp-2971	328	15	--	--	PUNCT
fnp-2971	328	16	a	a	DET
fnp-2971	328	17	role	role	NOUN
fnp-2971	328	18	for	for	ADP
fnp-2971	328	19	oxidative	oxidative	ADJ
fnp-2971	328	20	damage	damage	NOUN
fnp-2971	328	21	.	.	PUNCT
fnp-2971	329	1	j	j	PROPN
fnp-2971	329	2	neuropathol	neuropathol	PROPN
fnp-2971	329	3	exp	exp	PROPN
fnp-2971	329	4	neurol	neurol	PROPN
fnp-2971	329	5	2007:66;660	2007:66;660	NUM
fnp-2971	329	6	-	-	SYM
fnp-2971	329	7	72	72	NUM
fnp-2971	329	8	.	.	PUNCT
fnp-2971	330	1	34	34	NUM
fnp-2971	330	2	.	.	PUNCT
fnp-2971	330	3	tarumi	tarumi	PROPN
fnp-2971	330	4	t	t	PROPN
fnp-2971	330	5	,	,	PUNCT
fnp-2971	330	6	zhang	zhang	PROPN
fnp-2971	330	7	r.	r.	PROPN
fnp-2971	330	8	cerebral	cerebral	PROPN
fnp-2971	330	9	blood	blood	NOUN
fnp-2971	330	10	flow	flow	NOUN
fnp-2971	330	11	in	in	ADP
fnp-2971	330	12	normal	normal	ADJ
fnp-2971	330	13	aging	age	VERB
fnp-2971	330	14	adults	adult	NOUN
fnp-2971	330	15	:	:	PUNCT
fnp-2971	330	16	cardiovascular	cardiovascular	ADJ
fnp-2971	330	17	determinants	determinant	NOUN
fnp-2971	330	18	,	,	PUNCT
fnp-2971	330	19	clinical	clinical	ADJ
fnp-2971	330	20	implications	implication	NOUN
fnp-2971	330	21	,	,	PUNCT
fnp-2971	330	22	and	and	CCONJ
fnp-2971	330	23	aerobic	aerobic	ADJ
fnp-2971	330	24	fitness	fitness	NOUN
fnp-2971	330	25	.	.	PUNCT
fnp-2971	331	1	j	j	PROPN
fnp-2971	332	1	neurochem	neurochem	PROPN
fnp-2971	332	2	2018:144;595	2018:144;595	PROPN
fnp-2971	332	3	-	-	SYM
fnp-2971	332	4	608	608	NUM
fnp-2971	332	5	.	.	PUNCT
fnp-2971	332	6	35	35	NUM
fnp-2971	332	7	.	.	PUNCT
fnp-2971	332	8	eichler	eichler	PROPN
fnp-2971	332	9	fs	fs	PROPN
fnp-2971	332	10	,	,	PUNCT
fnp-2971	332	11	li	li	PROPN
fnp-2971	332	12	j	j	PROPN
fnp-2971	332	13	,	,	PUNCT
fnp-2971	332	14	guo	guo	PROPN
fnp-2971	332	15	y	y	PROPN
fnp-2971	332	16	,	,	PUNCT
fnp-2971	332	17	caruso	caruso	PROPN
fnp-2971	332	18	pa	pa	PROPN
fnp-2971	332	19	,	,	PUNCT
fnp-2971	332	20	bjonnes	bjonnes	PROPN
fnp-2971	332	21	ac	ac	PROPN
fnp-2971	332	22	,	,	PUNCT
fnp-2971	332	23	pan	pan	PROPN
fnp-2971	332	24	j	j	PROPN
fnp-2971	332	25	,	,	PUNCT
fnp-2971	332	26	booker	booker	PROPN
fnp-2971	332	27	jk	jk	PROPN
fnp-2971	332	28	,	,	PUNCT
fnp-2971	332	29	lane	lane	PROPN
fnp-2971	332	30	jm	jm	PROPN
fnp-2971	332	31	,	,	PUNCT
fnp-2971	332	32	tare	tare	PROPN
fnp-2971	332	33	a	a	PRON
fnp-2971	332	34	,	,	PUNCT
fnp-2971	332	35	vlasac	vlasac	NOUN
fnp-2971	332	36	i	i	PROPN
fnp-2971	332	37	,	,	PUNCT
fnp-2971	332	38	hakonarson	hakonarson	PROPN
fnp-2971	332	39	h	h	PROPN
fnp-2971	332	40	,	,	PUNCT
fnp-2971	332	41	gusella	gusella	PROPN
fnp-2971	332	42	jf	jf	PROPN
fnp-2971	332	43	,	,	PUNCT
fnp-2971	332	44	zhang	zhang	PROPN
fnp-2971	332	45	j	j	PROPN
fnp-2971	332	46	,	,	PUNCT
fnp-2971	332	47	keating	keating	NOUN
fnp-2971	332	48	bj	bj	PROPN
fnp-2971	332	49	,	,	PUNCT
fnp-2971	332	50	saxena	saxena	PROPN
fnp-2971	332	51	r.	r.	PROPN
fnp-2971	332	52	csf1r	csf1r	PROPN
fnp-2971	332	53	mosaicism	mosaicism	NOUN
fnp-2971	332	54	in	in	ADP
fnp-2971	332	55	a	a	DET
fnp-2971	332	56	family	family	NOUN
fnp-2971	332	57	with	with	ADP
fnp-2971	332	58	hereditary	hereditary	ADJ
fnp-2971	332	59	diffuse	diffuse	NOUN
fnp-2971	332	60	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	332	61	with	with	ADP
fnp-2971	332	62	spheroids	spheroid	NOUN
fnp-2971	332	63	.	.	PUNCT
fnp-2971	333	1	brain	brain	PROPN
fnp-2971	333	2	2016:139;1666	2016:139;1666	PROPN
fnp-2971	333	3	-	-	PUNCT
fnp-2971	333	4	72	72	NUM
fnp-2971	333	5	.	.	PUNCT
fnp-2971	334	1	36	36	NUM
fnp-2971	334	2	.	.	PUNCT
fnp-2971	335	1	gelfand	gelfand	PROPN
fnp-2971	335	2	jm	jm	PROPN
fnp-2971	335	3	,	,	PUNCT
fnp-2971	335	4	greenfield	greenfield	PROPN
fnp-2971	335	5	al	al	PROPN
fnp-2971	335	6	,	,	PUNCT
fnp-2971	335	7	barkovich	barkovich	PROPN
fnp-2971	335	8	m	m	PROPN
fnp-2971	335	9	,	,	PUNCT
fnp-2971	335	10	mendelsohn	mendelsohn	PROPN
fnp-2971	335	11	ba	ba	PROPN
fnp-2971	335	12	,	,	PUNCT
fnp-2971	335	13	van	van	PROPN
fnp-2971	335	14	haren	haren	PROPN
fnp-2971	335	15	k	k	PROPN
fnp-2971	335	16	,	,	PUNCT
fnp-2971	335	17	hess	hess	PROPN
fnp-2971	335	18	cp	cp	PROPN
fnp-2971	335	19	,	,	PUNCT
fnp-2971	335	20	mannis	mannis	PROPN
fnp-2971	335	21	gn	gn	PROPN
fnp-2971	335	22	.	.	PROPN
fnp-2971	335	23	allogeneic	allogeneic	PROPN
fnp-2971	335	24	hsct	hsct	PROPN
fnp-2971	335	25	for	for	ADP
fnp-2971	335	26	adult	adult	NOUN
fnp-2971	335	27	-	-	PUNCT
fnp-2971	335	28	onset	onset	NOUN
fnp-2971	335	29	leukoencephalopathy	leukoencephalopathy	ADV
fnp-2971	335	30	with	with	ADP
fnp-2971	335	31	spheroids	spheroid	NOUN
fnp-2971	335	32	and	and	CCONJ
fnp-2971	335	33	pigmented	pigmented	ADJ
fnp-2971	335	34	glia	glia	NOUN
fnp-2971	335	35	.	.	PUNCT
fnp-2971	336	1	brain	brain	NOUN
fnp-2971	336	2	2020:143;503	2020:143;503	NUM
fnp-2971	336	3	-	-	SYM
fnp-2971	336	4	11	11	NUM
fnp-2971	336	5	.	.	PUNCT
fnp-2971	337	1	copyright	copyright	NOUN
fnp-2971	337	2	:	:	PUNCT
fnp-2971	337	3	©	©	PROPN
fnp-2971	337	4	2020	2020	NUM
fnp-2971	337	5	the	the	DET
fnp-2971	337	6	author(s	author(s	NOUN
fnp-2971	337	7	)	)	PUNCT
fnp-2971	337	8	.	.	PUNCT
fnp-2971	338	1	this	this	PRON
fnp-2971	338	2	is	be	AUX
fnp-2971	338	3	an	an	DET
fnp-2971	338	4	open	open	ADJ
fnp-2971	338	5	access	access	NOUN
fnp-2971	338	6	article	article	NOUN
fnp-2971	338	7	distributed	distribute	VERB
fnp-2971	338	8	under	under	ADP
fnp-2971	338	9	the	the	DET
fnp-2971	338	10	terms	term	NOUN
fnp-2971	338	11	of	of	ADP
fnp-2971	338	12	the	the	DET
fnp-2971	338	13	creative	creative	ADJ
fnp-2971	338	14	commons	common	NOUN
fnp-2971	338	15	attribution	attribution	NOUN
fnp-2971	338	16	4.0	4.0	NUM
fnp-2971	338	17	international	international	ADJ
fnp-2971	338	18	license	license	NOUN
fnp-2971	338	19	(	(	PUNCT
fnp-2971	338	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-2971	338	21	)	)	PUNCT
fnp-2971	338	22	,	,	PUNCT
fnp-2971	338	23	which	which	PRON
fnp-2971	338	24	permits	permit	VERB
fnp-2971	338	25	unrestricted	unrestricted	ADJ
fnp-2971	338	26	use	use	NOUN
fnp-2971	338	27	,	,	PUNCT
fnp-2971	338	28	distribution	distribution	NOUN
fnp-2971	338	29	,	,	PUNCT
fnp-2971	338	30	and	and	CCONJ
fnp-2971	338	31	reproduction	reproduction	NOUN
fnp-2971	338	32	in	in	ADP
fnp-2971	338	33	any	any	DET
fnp-2971	338	34	medium	medium	NOUN
fnp-2971	338	35	,	,	PUNCT
fnp-2971	338	36	provided	provide	VERB
fnp-2971	338	37	the	the	DET
fnp-2971	338	38	original	original	ADJ
fnp-2971	338	39	author	author	NOUN
fnp-2971	338	40	and	and	CCONJ
fnp-2971	338	41	source	source	NOUN
fnp-2971	338	42	are	be	AUX
fnp-2971	338	43	credited	credit	VERB
fnp-2971	338	44	,	,	PUNCT
fnp-2971	338	45	a	a	DET
fnp-2971	338	46	link	link	NOUN
fnp-2971	338	47	to	to	ADP
fnp-2971	338	48	the	the	DET
fnp-2971	338	49	creative	creative	ADJ
fnp-2971	338	50	commons	common	NOUN
fnp-2971	338	51	license	license	NOUN
fnp-2971	338	52	is	be	AUX
fnp-2971	338	53	provided	provide	VERB
fnp-2971	338	54	,	,	PUNCT
fnp-2971	338	55	and	and	CCONJ
fnp-2971	338	56	any	any	DET
fnp-2971	338	57	changes	change	NOUN
fnp-2971	338	58	are	be	AUX
fnp-2971	338	59	indicated	indicate	VERB
fnp-2971	338	60	.	.	PUNCT
fnp-2971	339	1	the	the	DET
fnp-2971	339	2	creative	creative	ADJ
fnp-2971	339	3	commons	common	NOUN
fnp-2971	339	4	public	public	ADJ
fnp-2971	339	5	domain	domain	NOUN
fnp-2971	339	6	dedication	dedication	NOUN
fnp-2971	339	7	waiver	waiver	NOUN
fnp-2971	339	8	(	(	PUNCT
fnp-2971	339	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-2971	339	10	)	)	PUNCT
fnp-2971	339	11	applies	apply	VERB
fnp-2971	339	12	to	to	ADP
fnp-2971	339	13	the	the	DET
fnp-2971	339	14	data	datum	NOUN
fnp-2971	339	15	made	make	VERB
fnp-2971	339	16	available	available	ADJ
fnp-2971	339	17	in	in	ADP
fnp-2971	339	18	this	this	DET
fnp-2971	339	19	article	article	NOUN
fnp-2971	339	20	,	,	PUNCT
fnp-2971	339	21	unless	unless	SCONJ
fnp-2971	339	22	otherwise	otherwise	ADV
fnp-2971	339	23	stated	state	VERB
