id	sid	tid	token	lemma	pos
fnp-3025	1	1	aβ	aβ	PRON
fnp-3025	1	2	plaques	plaque	NOUN
fnp-3025	1	3	feel	feel	VERB
fnp-3025	1	4	free	free	ADJ
fnp-3025	1	5	to	to	PART
fnp-3025	1	6	add	add	VERB
fnp-3025	1	7	comments	comment	NOUN
fnp-3025	1	8	by	by	ADP
fnp-3025	1	9	clicking	click	VERB
fnp-3025	1	10	these	these	DET
fnp-3025	1	11	icons	icon	NOUN
fnp-3025	1	12	on	on	ADP
fnp-3025	1	13	the	the	DET
fnp-3025	1	14	sidebar	sidebar	NOUN
fnp-3025	1	15	free	free	ADJ
fnp-3025	1	16	neuropathology	neuropathology	NOUN
fnp-3025	1	17	1:31	1:31	NUM
fnp-3025	1	18	(	(	PUNCT
fnp-3025	1	19	2020	2020	NUM
fnp-3025	1	20	)	)	PUNCT
fnp-3025	1	21	review	review	VERB
fnp-3025	2	1	aβ	aβ	PRON
fnp-3025	2	2	plaques	plaque	NOUN
fnp-3025	2	3	lary	lary	PROPN
fnp-3025	2	4	c.	c.	PROPN
fnp-3025	2	5	walker	walker	PROPN
fnp-3025	2	6	department	department	PROPN
fnp-3025	2	7	of	of	ADP
fnp-3025	2	8	neurology	neurology	NOUN
fnp-3025	2	9	and	and	CCONJ
fnp-3025	2	10	yerkes	yerke	VERB
fnp-3025	2	11	national	national	ADJ
fnp-3025	2	12	primate	primate	NOUN
fnp-3025	2	13	research	research	NOUN
fnp-3025	2	14	center	center	NOUN
fnp-3025	2	15	,	,	PUNCT
fnp-3025	2	16	emory	emory	PROPN
fnp-3025	2	17	university	university	PROPN
fnp-3025	2	18	corresponding	corresponding	ADJ
fnp-3025	2	19	author	author	NOUN
fnp-3025	2	20	:	:	PUNCT
fnp-3025	2	21	lary	lary	PROPN
fnp-3025	2	22	c.	c.	PROPN
fnp-3025	2	23	walker	walker	PROPN
fnp-3025	2	24	·	·	PUNCT
fnp-3025	2	25	department	department	PROPN
fnp-3025	2	26	of	of	ADP
fnp-3025	2	27	neurology	neurology	NOUN
fnp-3025	2	28	·	·	SYM
fnp-3025	2	29	emory	emory	PROPN
fnp-3025	2	30	university	university	PROPN
fnp-3025	2	31	·	·	PUNCT
fnp-3025	2	32	505	505	NUM
fnp-3025	2	33	whitehead	whitehead	PROPN
fnp-3025	2	34	biomedical	biomedical	ADJ
fnp-3025	2	35	research	research	PROPN
fnp-3025	2	36	building	building	PROPN
fnp-3025	2	37	·	·	PUNCT
fnp-3025	2	38	615	615	NUM
fnp-3025	2	39	michael	michael	PROPN
fnp-3025	2	40	st	st	PROPN
fnp-3025	2	41	·	·	PROPN
fnp-3025	2	42	atlanta	atlanta	PROPN
fnp-3025	2	43	,	,	PUNCT
fnp-3025	2	44	ga	ga	PROPN
fnp-3025	2	45	30322	30322	NUM
fnp-3025	2	46	·	·	PUNCT
fnp-3025	2	47	usa	usa	PROPN
fnp-3025	2	48	lary.walker@emory.edu	lary.walker@emory.edu	PROPN
fnp-3025	2	49	submitted	submit	VERB
fnp-3025	2	50	:	:	PUNCT
fnp-3025	2	51	27	27	NUM
fnp-3025	2	52	september	september	PROPN
fnp-3025	2	53	2020	2020	NUM
fnp-3025	2	54	accepted	accept	VERB
fnp-3025	2	55	:	:	PUNCT
fnp-3025	2	56	23	23	NUM
fnp-3025	2	57	october	october	PROPN
fnp-3025	2	58	2020	2020	NUM
fnp-3025	2	59	copyedited	copyedit	VERB
fnp-3025	2	60	by	by	ADP
fnp-3025	2	61	:	:	PUNCT
fnp-3025	2	62	bert	bert	PROPN
fnp-3025	2	63	m.	m.	PROPN
fnp-3025	2	64	verheijen	verheijen	PROPN
fnp-3025	2	65	published	publish	VERB
fnp-3025	2	66	:	:	PUNCT
fnp-3025	2	67	30	30	NUM
fnp-3025	2	68	october	october	NOUN
fnp-3025	2	69	2020	2020	NUM
fnp-3025	2	70	https://doi.org/10.17879/freeneuropathology-2020-3025	https://doi.org/10.17879/freeneuropathology-2020-3025	PROPN
fnp-3025	2	71	keywords	keyword	NOUN
fnp-3025	2	72	:	:	PUNCT
fnp-3025	2	73	alzheimer	alzheimer	PROPN
fnp-3025	2	74	’s	’s	PART
fnp-3025	2	75	disease	disease	NOUN
fnp-3025	2	76	,	,	PUNCT
fnp-3025	2	77	amyloid	amyloid	NOUN
fnp-3025	2	78	,	,	PUNCT
fnp-3025	2	79	neuritic	neuritic	ADJ
fnp-3025	2	80	plaques	plaque	NOUN
fnp-3025	2	81	,	,	PUNCT
fnp-3025	2	82	neurofibrillary	neurofibrillary	ADJ
fnp-3025	2	83	tangles	tangle	NOUN
fnp-3025	2	84	,	,	PUNCT
fnp-3025	2	85	senile	senile	ADJ
fnp-3025	2	86	plaques	plaque	NOUN
fnp-3025	2	87	abstract	abstract	ADV
fnp-3025	2	88	aβ	aβ	DET
fnp-3025	2	89	plaques	plaque	NOUN
fnp-3025	2	90	are	be	AUX
fnp-3025	2	91	one	one	NUM
fnp-3025	2	92	of	of	ADP
fnp-3025	2	93	the	the	DET
fnp-3025	2	94	two	two	NUM
fnp-3025	2	95	lesions	lesion	NOUN
fnp-3025	2	96	in	in	ADP
fnp-3025	2	97	the	the	DET
fnp-3025	2	98	brain	brain	NOUN
fnp-3025	2	99	that	that	PRON
fnp-3025	2	100	define	define	VERB
fnp-3025	2	101	the	the	DET
fnp-3025	2	102	neuropathological	neuropathological	ADJ
fnp-3025	2	103	diagnosis	diagnosis	NOUN
fnp-3025	2	104	of	of	ADP
fnp-3025	2	105	alzheimer	alzheimer	PROPN
fnp-3025	2	106	’s	’s	PART
fnp-3025	2	107	disease	disease	NOUN
fnp-3025	2	108	.	.	PUNCT
fnp-3025	3	1	plaques	plaque	NOUN
fnp-3025	3	2	are	be	AUX
fnp-3025	3	3	highly	highly	ADV
fnp-3025	3	4	diverse	diverse	ADJ
fnp-3025	3	5	structures	structure	NOUN
fnp-3025	3	6	;	;	PUNCT
fnp-3025	3	7	many	many	ADJ
fnp-3025	3	8	of	of	ADP
fnp-3025	3	9	them	they	PRON
fnp-3025	3	10	include	include	VERB
fnp-3025	3	11	massed	mass	VERB
fnp-3025	3	12	,	,	PUNCT
fnp-3025	3	13	fibrillar	fibrillar	ADJ
fnp-3025	3	14	polymers	polymer	NOUN
fnp-3025	3	15	of	of	ADP
fnp-3025	3	16	the	the	DET
fnp-3025	3	17	aβ	aβ	NOUN
fnp-3025	3	18	protein	protein	NOUN
fnp-3025	3	19	referred	refer	VERB
fnp-3025	3	20	to	to	ADP
fnp-3025	3	21	as	as	ADP
fnp-3025	3	22	aβ	aβ	NOUN
fnp-3025	3	23	-	-	PUNCT
fnp-3025	3	24	amyloid	amyloid	NOUN
fnp-3025	3	25	,	,	PUNCT
fnp-3025	3	26	but	but	CCONJ
fnp-3025	3	27	some	some	PRON
fnp-3025	3	28	lack	lack	VERB
fnp-3025	3	29	the	the	DET
fnp-3025	3	30	defining	define	VERB
fnp-3025	3	31	features	feature	NOUN
fnp-3025	3	32	of	of	ADP
fnp-3025	3	33	amyloid	amyloid	NOUN
fnp-3025	3	34	.	.	PUNCT
fnp-3025	4	1	cellular	cellular	ADJ
fnp-3025	4	2	elements	element	NOUN
fnp-3025	4	3	in	in	ADP
fnp-3025	4	4	‘	'	PUNCT
fnp-3025	4	5	classical	classical	ADJ
fnp-3025	4	6	’	'	PUNCT
fnp-3025	4	7	plaques	plaque	NOUN
fnp-3025	4	8	include	include	VERB
fnp-3025	4	9	abnormal	abnormal	ADJ
fnp-3025	4	10	neuronal	neuronal	ADJ
fnp-3025	4	11	processes	process	NOUN
fnp-3025	4	12	and	and	CCONJ
fnp-3025	4	13	reactive	reactive	ADJ
fnp-3025	4	14	glial	glial	ADJ
fnp-3025	4	15	cells	cell	NOUN
fnp-3025	4	16	,	,	PUNCT
fnp-3025	4	17	but	but	CCONJ
fnp-3025	4	18	these	these	PRON
fnp-3025	4	19	are	be	AUX
fnp-3025	4	20	not	not	PART
fnp-3025	4	21	present	present	ADJ
fnp-3025	4	22	in	in	ADP
fnp-3025	4	23	all	all	DET
fnp-3025	4	24	plaques	plaque	NOUN
fnp-3025	4	25	.	.	PUNCT
fnp-3025	5	1	plaques	plaque	NOUN
fnp-3025	5	2	have	have	AUX
fnp-3025	5	3	been	be	AUX
fnp-3025	5	4	given	give	VERB
fnp-3025	5	5	various	various	ADJ
fnp-3025	5	6	names	name	NOUN
fnp-3025	5	7	since	since	SCONJ
fnp-3025	5	8	their	their	PRON
fnp-3025	5	9	discovery	discovery	NOUN
fnp-3025	5	10	in	in	ADP
fnp-3025	5	11	1892	1892	NUM
fnp-3025	5	12	,	,	PUNCT
fnp-3025	5	13	including	include	VERB
fnp-3025	5	14	senile	senile	ADJ
fnp-3025	5	15	plaques	plaque	NOUN
fnp-3025	5	16	,	,	PUNCT
fnp-3025	5	17	amyloid	amyloid	NOUN
fnp-3025	5	18	plaques	plaque	NOUN
fnp-3025	5	19	,	,	PUNCT
fnp-3025	5	20	and	and	CCONJ
fnp-3025	5	21	neuritic	neuritic	ADJ
fnp-3025	5	22	plaques	plaque	NOUN
fnp-3025	5	23	.	.	PUNCT
fnp-3025	6	1	however	however	ADV
fnp-3025	6	2	,	,	PUNCT
fnp-3025	6	3	with	with	ADP
fnp-3025	6	4	the	the	DET
fnp-3025	6	5	identification	identification	NOUN
fnp-3025	6	6	in	in	ADP
fnp-3025	6	7	the	the	DET
fnp-3025	6	8	1980s	1980	NOUN
fnp-3025	6	9	of	of	ADP
fnp-3025	6	10	aβ	aβ	NOUN
fnp-3025	6	11	as	as	ADP
fnp-3025	6	12	the	the	DET
fnp-3025	6	13	obligatory	obligatory	ADJ
fnp-3025	6	14	and	and	CCONJ
fnp-3025	6	15	universal	universal	ADJ
fnp-3025	6	16	component	component	NOUN
fnp-3025	6	17	of	of	ADP
fnp-3025	6	18	plaques	plaque	NOUN
fnp-3025	6	19	,	,	PUNCT
fnp-3025	6	20	the	the	DET
fnp-3025	6	21	term	term	NOUN
fnp-3025	6	22	‘	'	PUNCT
fnp-3025	6	23	aβ	aβ	DET
fnp-3025	6	24	plaques	plaque	NOUN
fnp-3025	6	25	’	'	PUNCT
fnp-3025	6	26	has	have	AUX
fnp-3025	6	27	become	become	VERB
fnp-3025	6	28	a	a	DET
fnp-3025	6	29	unifying	unifying	ADJ
fnp-3025	6	30	term	term	NOUN
fnp-3025	6	31	for	for	ADP
fnp-3025	6	32	these	these	DET
fnp-3025	6	33	heterogeneous	heterogeneous	ADJ
fnp-3025	6	34	formations	formation	NOUN
fnp-3025	6	35	.	.	PUNCT
fnp-3025	7	1	tauopathy	tauopathy	PROPN
fnp-3025	7	2	,	,	PUNCT
fnp-3025	7	3	the	the	DET
fnp-3025	7	4	second	second	ADJ
fnp-3025	7	5	essential	essential	ADJ
fnp-3025	7	6	lesion	lesion	NOUN
fnp-3025	7	7	of	of	ADP
fnp-3025	7	8	the	the	DET
fnp-3025	7	9	alzheimer	alzheimer	PROPN
fnp-3025	7	10	’s	’s	PART
fnp-3025	7	11	disease	disease	NOUN
fnp-3025	7	12	diagnostic	diagnostic	ADJ
fnp-3025	7	13	dyad	dyad	NOUN
fnp-3025	7	14	,	,	PUNCT
fnp-3025	7	15	is	be	AUX
fnp-3025	7	16	downstream	downstream	ADJ
fnp-3025	7	17	of	of	ADP
fnp-3025	7	18	aβ	aβ	NOUN
fnp-3025	7	19	-	-	PUNCT
fnp-3025	7	20	proteopathy	proteopathy	ADJ
fnp-3025	7	21	,	,	PUNCT
fnp-3025	7	22	but	but	CCONJ
fnp-3025	7	23	it	it	PRON
fnp-3025	7	24	is	be	AUX
fnp-3025	7	25	critically	critically	ADV
fnp-3025	7	26	important	important	ADJ
fnp-3025	7	27	for	for	ADP
fnp-3025	7	28	the	the	DET
fnp-3025	7	29	manifestation	manifestation	NOUN
fnp-3025	7	30	of	of	ADP
fnp-3025	7	31	dementia	dementia	NOUN
fnp-3025	7	32	.	.	PUNCT
fnp-3025	8	1	the	the	DET
fnp-3025	8	2	etiologic	etiologic	ADJ
fnp-3025	8	3	link	link	NOUN
fnp-3025	8	4	between	between	ADP
fnp-3025	8	5	aβ	aβ	NOUN
fnp-3025	8	6	-	-	PUNCT
fnp-3025	8	7	proteopathy	proteopathy	ADJ
fnp-3025	8	8	and	and	CCONJ
fnp-3025	8	9	tauopathy	tauopathy	NOUN
fnp-3025	8	10	in	in	ADP
fnp-3025	8	11	alzheimer	alzheimer	PROPN
fnp-3025	8	12	’s	’s	PART
fnp-3025	8	13	disease	disease	NOUN
fnp-3025	8	14	remains	remain	VERB
fnp-3025	8	15	largely	largely	ADV
fnp-3025	8	16	undefined	undefined	ADJ
fnp-3025	8	17	.	.	PUNCT
fnp-3025	9	1	aβ	aβ	DET
fnp-3025	9	2	plaques	plaque	NOUN
fnp-3025	9	3	develop	develop	VERB
fnp-3025	9	4	and	and	CCONJ
fnp-3025	9	5	propagate	propagate	VERB
fnp-3025	9	6	via	via	ADP
fnp-3025	9	7	the	the	DET
fnp-3025	9	8	misfolding	misfolding	ADJ
fnp-3025	9	9	,	,	PUNCT
fnp-3025	9	10	self	self	NOUN
fnp-3025	9	11	-	-	PUNCT
fnp-3025	9	12	assembly	assembly	NOUN
fnp-3025	9	13	and	and	CCONJ
fnp-3025	9	14	spread	spread	NOUN
fnp-3025	9	15	of	of	ADP
fnp-3025	9	16	aβ	aβ	NOUN
fnp-3025	9	17	by	by	ADP
fnp-3025	9	18	the	the	DET
fnp-3025	9	19	prion	prion	NOUN
fnp-3025	9	20	-	-	PUNCT
fnp-3025	9	21	like	like	ADJ
fnp-3025	9	22	mechanism	mechanism	NOUN
fnp-3025	9	23	of	of	ADP
fnp-3025	9	24	seeded	seeded	ADJ
fnp-3025	9	25	protein	protein	NOUN
fnp-3025	9	26	aggregation	aggregation	NOUN
fnp-3025	9	27	.	.	PUNCT
fnp-3025	10	1	partially	partially	ADV
fnp-3025	10	2	overlapping	overlap	VERB
fnp-3025	10	3	sets	set	NOUN
fnp-3025	10	4	of	of	ADP
fnp-3025	10	5	risk	risk	NOUN
fnp-3025	10	6	factors	factor	NOUN
fnp-3025	10	7	and	and	CCONJ
fnp-3025	10	8	sequelae	sequelae	NOUN
fnp-3025	10	9	,	,	PUNCT
fnp-3025	10	10	including	include	VERB
fnp-3025	10	11	inflammation	inflammation	NOUN
fnp-3025	10	12	,	,	PUNCT
fnp-3025	10	13	genetic	genetic	ADJ
fnp-3025	10	14	variations	variation	NOUN
fnp-3025	10	15	,	,	PUNCT
fnp-3025	10	16	and	and	CCONJ
fnp-3025	10	17	various	various	ADJ
fnp-3025	10	18	environmental	environmental	ADJ
fnp-3025	10	19	triggers	trigger	NOUN
fnp-3025	10	20	have	have	AUX
fnp-3025	10	21	been	be	AUX
fnp-3025	10	22	linked	link	VERB
fnp-3025	10	23	to	to	ADP
fnp-3025	10	24	plaque	plaque	NOUN
fnp-3025	10	25	development	development	NOUN
fnp-3025	10	26	and	and	CCONJ
fnp-3025	10	27	idiopathic	idiopathic	ADJ
fnp-3025	10	28	alzheimer	alzheimer	PROPN
fnp-3025	10	29	’s	’s	PART
fnp-3025	10	30	disease	disease	NOUN
fnp-3025	10	31	,	,	PUNCT
fnp-3025	10	32	but	but	CCONJ
fnp-3025	10	33	no	no	DET
fnp-3025	10	34	single	single	ADJ
fnp-3025	10	35	factor	factor	NOUN
fnp-3025	10	36	has	have	AUX
fnp-3025	10	37	emerged	emerge	VERB
fnp-3025	10	38	as	as	ADP
fnp-3025	10	39	a	a	DET
fnp-3025	10	40	requisite	requisite	ADJ
fnp-3025	10	41	cause	cause	NOUN
fnp-3025	10	42	.	.	PUNCT
fnp-3025	11	1	the	the	DET
fnp-3025	11	2	value	value	NOUN
fnp-3025	11	3	of	of	ADP
fnp-3025	11	4	aβ	aβ	ADP
fnp-3025	11	5	plaques	plaque	NOUN
fnp-3025	11	6	per	per	ADV
fnp-3025	11	7	se	se	ADV
fnp-3025	11	8	as	as	ADP
fnp-3025	11	9	therapeutic	therapeutic	ADJ
fnp-3025	11	10	targets	target	NOUN
fnp-3025	11	11	is	be	AUX
fnp-3025	11	12	uncertain	uncertain	ADJ
fnp-3025	11	13	;	;	PUNCT
fnp-3025	11	14	although	although	SCONJ
fnp-3025	11	15	some	some	DET
fnp-3025	11	16	plaques	plaque	NOUN
fnp-3025	11	17	are	be	AUX
fnp-3025	11	18	sites	site	NOUN
fnp-3025	11	19	of	of	ADP
fnp-3025	11	20	focal	focal	ADJ
fnp-3025	11	21	gliosis	gliosis	NOUN
fnp-3025	11	22	and	and	CCONJ
fnp-3025	11	23	inflammation	inflammation	NOUN
fnp-3025	11	24	,	,	PUNCT
fnp-3025	11	25	the	the	DET
fnp-3025	11	26	complexity	complexity	NOUN
fnp-3025	11	27	of	of	ADP
fnp-3025	11	28	inflammatory	inflammatory	ADJ
fnp-3025	11	29	biology	biology	NOUN
fnp-3025	11	30	presents	present	VERB
fnp-3025	11	31	challenges	challenge	NOUN
fnp-3025	11	32	to	to	ADP
fnp-3025	11	33	glia	glia	NOUN
fnp-3025	11	34	-	-	PUNCT
fnp-3025	11	35	directed	direct	VERB
fnp-3025	11	36	intervention	intervention	NOUN
fnp-3025	11	37	.	.	PUNCT
fnp-3025	12	1	small	small	ADJ
fnp-3025	12	2	,	,	PUNCT
fnp-3025	12	3	soluble	soluble	ADJ
fnp-3025	12	4	,	,	PUNCT
fnp-3025	12	5	oligomeric	oligomeric	ADJ
fnp-3025	12	6	assemblies	assembly	NOUN
fnp-3025	12	7	of	of	ADP
fnp-3025	12	8	aβ	aβ	PRON
fnp-3025	12	9	are	be	AUX
fnp-3025	12	10	enriched	enrich	VERB
fnp-3025	12	11	in	in	ADP
fnp-3025	12	12	the	the	DET
fnp-3025	12	13	vicinity	vicinity	NOUN
fnp-3025	12	14	of	of	ADP
fnp-3025	12	15	plaques	plaque	NOUN
fnp-3025	12	16	,	,	PUNCT
fnp-3025	12	17	and	and	CCONJ
fnp-3025	12	18	these	these	PRON
fnp-3025	12	19	probably	probably	ADV
fnp-3025	12	20	contribute	contribute	VERB
fnp-3025	12	21	to	to	ADP
fnp-3025	12	22	the	the	DET
fnp-3025	12	23	toxic	toxic	ADJ
fnp-3025	12	24	impact	impact	NOUN
fnp-3025	12	25	of	of	ADP
fnp-3025	12	26	aβ	aβ	DET
fnp-3025	12	27	aggregation	aggregation	NOUN
fnp-3025	12	28	on	on	ADP
fnp-3025	12	29	the	the	DET
fnp-3025	12	30	brain	brain	NOUN
fnp-3025	12	31	.	.	PUNCT
fnp-3025	13	1	measures	measure	NOUN
fnp-3025	13	2	designed	design	VERB
fnp-3025	13	3	to	to	PART
fnp-3025	13	4	reduce	reduce	VERB
fnp-3025	13	5	the	the	DET
fnp-3025	13	6	production	production	NOUN
fnp-3025	13	7	or	or	CCONJ
fnp-3025	13	8	seeded	seeded	ADJ
fnp-3025	13	9	self	self	NOUN
fnp-3025	13	10	-	-	PUNCT
fnp-3025	13	11	assembly	assembly	NOUN
fnp-3025	13	12	of	of	ADP
fnp-3025	13	13	aβ	aβ	NOUN
fnp-3025	13	14	can	can	AUX
fnp-3025	13	15	impede	impede	VERB
fnp-3025	13	16	the	the	DET
fnp-3025	13	17	formation	formation	NOUN
fnp-3025	13	18	of	of	ADP
fnp-3025	13	19	aβ	aβ	PRON
fnp-3025	13	20	plaques	plaque	NOUN
fnp-3025	13	21	and	and	CCONJ
fnp-3025	13	22	oligomers	oligomer	NOUN
fnp-3025	13	23	,	,	PUNCT
fnp-3025	13	24	along	along	ADP
fnp-3025	13	25	with	with	ADP
fnp-3025	13	26	their	their	PRON
fnp-3025	13	27	accompanying	accompany	VERB
fnp-3025	13	28	abnormalities	abnormality	NOUN
fnp-3025	13	29	;	;	PUNCT
fnp-3025	13	30	given	give	VERB
fnp-3025	13	31	the	the	DET
fnp-3025	13	32	apparent	apparent	ADJ
fnp-3025	13	33	long	long	ADJ
fnp-3025	13	34	timecourse	timecourse	NOUN
fnp-3025	13	35	of	of	ADP
fnp-3025	13	36	the	the	DET
fnp-3025	13	37	emergence	emergence	NOUN
fnp-3025	13	38	,	,	PUNCT
fnp-3025	13	39	maturation	maturation	NOUN
fnp-3025	13	40	and	and	CCONJ
fnp-3025	13	41	proliferation	proliferation	NOUN
fnp-3025	13	42	of	of	ADP
fnp-3025	13	43	aβ	aβ	DET
fnp-3025	13	44	plaques	plaque	NOUN
fnp-3025	13	45	in	in	ADP
fnp-3025	13	46	humans	human	NOUN
fnp-3025	13	47	,	,	PUNCT
fnp-3025	13	48	such	such	ADJ
fnp-3025	13	49	therapies	therapy	NOUN
fnp-3025	13	50	are	be	AUX
fnp-3025	13	51	likely	likely	ADJ
fnp-3025	13	52	to	to	PART
fnp-3025	13	53	be	be	AUX
fnp-3025	13	54	most	most	ADV
fnp-3025	13	55	effective	effective	ADJ
fnp-3025	13	56	when	when	SCONJ
fnp-3025	13	57	begun	begin	VERB
fnp-3025	13	58	early	early	ADV
fnp-3025	13	59	in	in	ADP
fnp-3025	13	60	the	the	DET
fnp-3025	13	61	pathogenic	pathogenic	ADJ
fnp-3025	13	62	process	process	NOUN
fnp-3025	13	63	,	,	PUNCT
fnp-3025	13	64	before	before	SCONJ
fnp-3025	13	65	significant	significant	ADJ
fnp-3025	13	66	damage	damage	NOUN
fnp-3025	13	67	has	have	AUX
fnp-3025	13	68	been	be	AUX
fnp-3025	13	69	done	do	VERB
fnp-3025	13	70	to	to	ADP
fnp-3025	13	71	the	the	DET
fnp-3025	13	72	brain	brain	NOUN
fnp-3025	13	73	.	.	PUNCT
fnp-3025	14	1	since	since	SCONJ
fnp-3025	14	2	their	their	PRON
fnp-3025	14	3	discovery	discovery	NOUN
fnp-3025	14	4	in	in	ADP
fnp-3025	14	5	the	the	DET
fnp-3025	14	6	late	late	ADJ
fnp-3025	14	7	19th	19th	ADJ
fnp-3025	14	8	century	century	NOUN
fnp-3025	14	9	,	,	PUNCT
fnp-3025	14	10	aβ	aβ	DET
fnp-3025	14	11	plaques	plaque	NOUN
fnp-3025	14	12	have	have	VERB
fnp-3025	14	13	,	,	PUNCT
fnp-3025	14	14	time	time	NOUN
fnp-3025	14	15	and	and	CCONJ
fnp-3025	14	16	again	again	ADV
fnp-3025	14	17	,	,	PUNCT
fnp-3025	14	18	illuminated	illuminate	VERB
fnp-3025	14	19	fundamental	fundamental	ADJ
fnp-3025	14	20	mechanisms	mechanism	NOUN
fnp-3025	14	21	driving	drive	VERB
fnp-3025	14	22	neurodegeneration	neurodegeneration	NOUN
fnp-3025	14	23	,	,	PUNCT
fnp-3025	14	24	and	and	CCONJ
fnp-3025	14	25	they	they	PRON
fnp-3025	14	26	should	should	AUX
fnp-3025	14	27	remain	remain	VERB
fnp-3025	14	28	at	at	ADP
fnp-3025	14	29	the	the	DET
fnp-3025	14	30	forefront	forefront	NOUN
fnp-3025	14	31	of	of	ADP
fnp-3025	14	32	efforts	effort	NOUN
fnp-3025	14	33	to	to	PART
fnp-3025	14	34	understand	understand	VERB
fnp-3025	14	35	,	,	PUNCT
fnp-3025	14	36	and	and	CCONJ
fnp-3025	14	37	therefore	therefore	ADV
fnp-3025	14	38	treat	treat	VERB
fnp-3025	14	39	,	,	PUNCT
fnp-3025	14	40	alzheimer	alzheimer	PROPN
fnp-3025	14	41	’s	’s	PART
fnp-3025	14	42	disease	disease	NOUN
fnp-3025	14	43	.	.	PUNCT
fnp-3025	15	1	1	1	X
fnp-3025	15	2	.	.	X
fnp-3025	15	3	aβ	aβ	PROPN
fnp-3025	15	4	,	,	PUNCT
fnp-3025	15	5	amyloid	amyloid	NOUN
fnp-3025	15	6	,	,	PUNCT
fnp-3025	15	7	and	and	CCONJ
fnp-3025	15	8	alzheimer	alzheimer	PROPN
fnp-3025	15	9	’s	’s	PART
fnp-3025	15	10	disease	disease	NOUN
fnp-3025	15	11	the	the	DET
fnp-3025	15	12	most	most	ADV
fnp-3025	15	13	striking	striking	ADJ
fnp-3025	15	14	and	and	CCONJ
fnp-3025	15	15	yet	yet	ADV
fnp-3025	15	16	still	still	ADV
fnp-3025	15	17	enigmatic	enigmatic	ADJ
fnp-3025	15	18	pathologic	pathologic	ADJ
fnp-3025	15	19	features	feature	NOUN
fnp-3025	15	20	of	of	ADP
fnp-3025	15	21	alzheimer	alzheimer	PROPN
fnp-3025	15	22	’s	’s	PART
fnp-3025	15	23	disease	disease	NOUN
fnp-3025	15	24	(	(	PUNCT
fnp-3025	15	25	ad	ad	NOUN
fnp-3025	15	26	)	)	PUNCT
fnp-3025	15	27	are	be	AUX
fnp-3025	15	28	lesions	lesion	NOUN
fnp-3025	15	29	known	know	VERB
fnp-3025	15	30	for	for	ADP
fnp-3025	15	31	over	over	ADP
fnp-3025	15	32	a	a	PRON
fnp-3025	15	33	century	century	NOUN
fnp-3025	15	34	as	as	ADP
fnp-3025	15	35	senile	senile	ADJ
fnp-3025	15	36	plaques	plaque	NOUN
fnp-3025	15	37	microscopic	microscopic	ADJ
fnp-3025	15	38	anomalies	anomaly	NOUN
fnp-3025	15	39	in	in	ADP
fnp-3025	15	40	the	the	DET
fnp-3025	15	41	parenchyma	parenchyma	NOUN
fnp-3025	15	42	of	of	ADP
fnp-3025	15	43	the	the	DET
fnp-3025	15	44	brain	brain	NOUN
fnp-3025	15	45	consisting	consist	VERB
fnp-3025	15	46	of	of	ADP
fnp-3025	15	47	an	an	DET
fnp-3025	15	48	abnormal	abnormal	ADJ
fnp-3025	15	49	accumulation	accumulation	NOUN
fnp-3025	15	50	of	of	ADP
fnp-3025	15	51	protein	protein	NOUN
fnp-3025	15	52	decorated	decorate	VERB
fnp-3025	15	53	by	by	ADP
fnp-3025	15	54	various	various	ADJ
fnp-3025	15	55	molecules	molecule	NOUN
fnp-3025	15	56	,	,	PUNCT
fnp-3025	15	57	and	and	CCONJ
fnp-3025	15	58	often	often	ADV
fnp-3025	15	59	including	include	VERB
fnp-3025	15	60	dystrophic	dystrophic	ADJ
fnp-3025	15	61	neuronal	neuronal	ADJ
fnp-3025	15	62	processes	process	NOUN
fnp-3025	15	63	and	and	CCONJ
fnp-3025	15	64	reactive	reactive	ADJ
fnp-3025	15	65	glial	glial	ADJ
fnp-3025	15	66	cells	cell	NOUN
fnp-3025	15	67	(	(	PUNCT
fnp-3025	15	68	figure	figure	NOUN
fnp-3025	15	69	1	1	NUM
fnp-3025	15	70	)	)	PUNCT
fnp-3025	15	71	.	.	PUNCT
fnp-3025	16	1	although	although	SCONJ
fnp-3025	16	2	plaques	plaque	NOUN
fnp-3025	16	3	are	be	AUX
fnp-3025	16	4	a	a	DET
fnp-3025	16	5	frequent	frequent	ADJ
fnp-3025	16	6	feature	feature	NOUN
fnp-3025	16	7	of	of	ADP
fnp-3025	16	8	the	the	DET
fnp-3025	16	9	senescent	senescent	ADJ
fnp-3025	16	10	brain	brain	NOUN
fnp-3025	16	11	and	and	CCONJ
fnp-3025	16	12	,	,	PUNCT
fnp-3025	16	13	when	when	SCONJ
fnp-3025	16	14	particularly	particularly	ADV
fnp-3025	16	15	numerous	numerous	ADJ
fnp-3025	16	16	,	,	PUNCT
fnp-3025	16	17	an	an	DET
fnp-3025	16	18	obligatory	obligatory	ADJ
fnp-3025	16	19	diagnostic	diagnostic	ADJ
fnp-3025	16	20	marker	marker	NOUN
fnp-3025	16	21	of	of	ADP
fnp-3025	16	22	ad	ad	NOUN
fnp-3025	16	23	[	[	X
fnp-3025	16	24	1	1	NUM
fnp-3025	16	25	]	]	PUNCT
fnp-3025	16	26	,	,	PUNCT
fnp-3025	16	27	the	the	DET
fnp-3025	16	28	identity	identity	NOUN
fnp-3025	16	29	of	of	ADP
fnp-3025	16	30	the	the	DET
fnp-3025	16	31	principal	principal	ADJ
fnp-3025	16	32	protein	protein	NOUN
fnp-3025	16	33	in	in	ADP
fnp-3025	16	34	the	the	DET
fnp-3025	16	35	plaque	plaque	NOUN
fnp-3025	16	36	core	core	NOUN
fnp-3025	16	37	remained	remain	VERB
fnp-3025	16	38	unknown	unknown	ADJ
fnp-3025	16	39	until	until	ADP
fnp-3025	16	40	the	the	DET
fnp-3025	16	41	1980s	1980s	NUM
fnp-3025	16	42	.	.	PUNCT
fnp-3025	17	1	then	then	ADV
fnp-3025	17	2	,	,	PUNCT
fnp-3025	17	3	glenner	glenner	NOUN
fnp-3025	17	4	and	and	CCONJ
fnp-3025	17	5	wong	wong	PROPN
fnp-3025	17	6	established	establish	VERB
fnp-3025	17	7	a	a	DET
fnp-3025	17	8	partial	partial	ADJ
fnp-3025	17	9	amino	amino	NOUN
fnp-3025	17	10	acid	acid	NOUN
fnp-3025	17	11	sequence	sequence	NOUN
fnp-3025	17	12	of	of	ADP
fnp-3025	17	13	the	the	DET
fnp-3025	17	14	protein	protein	NOUN
fnp-3025	17	15	in	in	ADP
fnp-3025	17	16	cerebral	cerebral	ADJ
fnp-3025	17	17	amyloid	amyloid	NOUN
fnp-3025	17	18	angiopathy	angiopathy	ADJ
fnp-3025	17	19	(	(	PUNCT
fnp-3025	17	20	caa	caa	NOUN
fnp-3025	17	21	)	)	PUNCT
fnp-3025	17	22	from	from	ADP
fnp-3025	17	23	patients	patient	NOUN
fnp-3025	17	24	with	with	ADP
fnp-3025	17	25	ad	ad	NOUN
fnp-3025	17	26	and	and	CCONJ
fnp-3025	17	27	down	down	ADP
fnp-3025	17	28	syndrome	syndrome	NOUN
fnp-3025	17	29	[	[	X
fnp-3025	17	30	2	2	NUM
fnp-3025	17	31	,	,	PUNCT
fnp-3025	17	32	3	3	NUM
fnp-3025	17	33	]	]	PUNCT
fnp-3025	17	34	,	,	PUNCT
fnp-3025	17	35	and	and	CCONJ
fnp-3025	17	36	masters	master	NOUN
fnp-3025	17	37	and	and	CCONJ
fnp-3025	17	38	beyreuther	beyreuther	NOUN
fnp-3025	17	39	[	[	X
fnp-3025	17	40	4	4	NUM
fnp-3025	17	41	,	,	PUNCT
fnp-3025	17	42	5	5	NUM
fnp-3025	17	43	]	]	PUNCT
fnp-3025	17	44	determined	determine	VERB
fnp-3025	17	45	that	that	SCONJ
fnp-3025	17	46	the	the	DET
fnp-3025	17	47	same	same	ADJ
fnp-3025	17	48	protein	protein	NOUN
fnp-3025	17	49	is	be	AUX
fnp-3025	17	50	a	a	DET
fnp-3025	17	51	key	key	ADJ
fnp-3025	17	52	component	component	NOUN
fnp-3025	17	53	of	of	ADP
fnp-3025	17	54	plaques	plaque	NOUN
fnp-3025	17	55	.	.	PUNCT
fnp-3025	18	1	initially	initially	ADV
fnp-3025	18	2	referred	refer	VERB
fnp-3025	18	3	to	to	ADP
fnp-3025	18	4	as	as	ADP
fnp-3025	18	5	the	the	DET
fnp-3025	18	6	β	β	NOUN
fnp-3025	18	7	protein	protein	NOUN
fnp-3025	18	8	,	,	PUNCT
fnp-3025	18	9	a4	a4	PROPN
fnp-3025	18	10	,	,	PUNCT
fnp-3025	18	11	or	or	CCONJ
fnp-3025	18	12	β	β	X
fnp-3025	18	13	/	/	SYM
fnp-3025	18	14	a4	a4	PROPN
fnp-3025	18	15	,	,	PUNCT
fnp-3025	18	16	the	the	DET
fnp-3025	18	17	protein	protein	NOUN
fnp-3025	18	18	now	now	ADV
fnp-3025	18	19	is	be	AUX
fnp-3025	18	20	commonly	commonly	ADV
fnp-3025	18	21	designated	designate	VERB
fnp-3025	18	22	aβ	aβ	ADP
fnp-3025	19	1	[	[	X
fnp-3025	19	2	6	6	NUM
fnp-3025	19	3	]	]	PUNCT
fnp-3025	19	4	.	.	PUNCT
fnp-3025	20	1	collectively	collectively	ADV
fnp-3025	20	2	,	,	PUNCT
fnp-3025	20	3	these	these	DET
fnp-3025	20	4	lesions	lesion	NOUN
fnp-3025	20	5	are	be	AUX
fnp-3025	20	6	increasingly	increasingly	ADV
fnp-3025	20	7	referred	refer	VERB
fnp-3025	20	8	to	to	ADP
fnp-3025	20	9	as	as	ADP
fnp-3025	20	10	aβ	aβ	PRON
fnp-3025	20	11	plaques	plaque	NOUN
fnp-3025	20	12	(	(	PUNCT
fnp-3025	20	13	see	see	VERB
fnp-3025	20	14	section	section	NOUN
fnp-3025	20	15	3	3	NUM
fnp-3025	20	16	)	)	PUNCT
fnp-3025	20	17	.	.	PUNCT
fnp-3025	21	1	figure	figure	VERB
fnp-3025	21	2	1	1	NUM
fnp-3025	21	3	.	.	PUNCT
fnp-3025	22	1	'	'	PUNCT
fnp-3025	22	2	classical	classical	ADJ
fnp-3025	22	3	'	'	PUNCT
fnp-3025	22	4	aβ	aβ	NOUN
fnp-3025	22	5	(	(	PUNCT
fnp-3025	22	6	senile	senile	NOUN
fnp-3025	22	7	)	)	PUNCT
fnp-3025	22	8	plaques	plaque	NOUN
fnp-3025	22	9	in	in	ADP
fnp-3025	22	10	the	the	DET
fnp-3025	22	11	cortex	cortex	NOUN
fnp-3025	22	12	of	of	ADP
fnp-3025	22	13	persons	person	NOUN
fnp-3025	22	14	who	who	PRON
fnp-3025	22	15	had	have	AUX
fnp-3025	22	16	died	die	VERB
fnp-3025	22	17	with	with	ADP
fnp-3025	22	18	alzheimer	alzheimer	PROPN
fnp-3025	22	19	's	's	PART
fnp-3025	22	20	disease	disease	NOUN
fnp-3025	22	21	(	(	PUNCT
fnp-3025	22	22	ad	ad	NOUN
fnp-3025	22	23	)	)	PUNCT
fnp-3025	22	24	.	.	PUNCT
fnp-3025	23	1	left	leave	VERB
fnp-3025	23	2	,	,	PUNCT
fnp-3025	23	3	a	a	DET
fnp-3025	23	4	plaque	plaque	NOUN
fnp-3025	23	5	stained	stain	VERB
fnp-3025	23	6	with	with	ADP
fnp-3025	23	7	the	the	DET
fnp-3025	23	8	naoumenko	naoumenko	NOUN
fnp-3025	23	9	-	-	PUNCT
fnp-3025	23	10	feigin	feigin	NOUN
fnp-3025	23	11	silver	silver	NOUN
fnp-3025	23	12	method	method	NOUN
fnp-3025	23	13	and	and	CCONJ
fnp-3025	23	14	periodic	periodic	ADJ
fnp-3025	23	15	acid	acid	NOUN
fnp-3025	23	16	-	-	PUNCT
fnp-3025	23	17	schiff	schiff	NOUN
fnp-3025	23	18	(	(	PUNCT
fnp-3025	23	19	pas	pas	NOUN
fnp-3025	23	20	)	)	PUNCT
fnp-3025	23	21	counterstain	counterstain	NOUN
fnp-3025	23	22	;	;	PUNCT
fnp-3025	23	23	an	an	DET
fnp-3025	23	24	amyloid	amyloid	NOUN
fnp-3025	23	25	core	core	NOUN
fnp-3025	23	26	(	(	PUNCT
fnp-3025	23	27	dark	dark	ADV
fnp-3025	23	28	pink	pink	ADJ
fnp-3025	23	29	)	)	PUNCT
fnp-3025	23	30	is	be	AUX
fnp-3025	23	31	surrounded	surround	VERB
fnp-3025	23	32	by	by	ADP
fnp-3025	23	33	profuse	profuse	PROPN
fnp-3025	23	34	abnormal	abnormal	ADJ
fnp-3025	23	35	neurites	neurite	NOUN
fnp-3025	23	36	(	(	PUNCT
fnp-3025	23	37	black	black	NOUN
fnp-3025	23	38	)	)	PUNCT
fnp-3025	23	39	.	.	PUNCT
fnp-3025	24	1	right	right	ADJ
fnp-3025	24	2	,	,	PUNCT
fnp-3025	24	3	a	a	DET
fnp-3025	24	4	plaque	plaque	NOUN
fnp-3025	24	5	immunostained	immunostaine	VERB
fnp-3025	24	6	with	with	ADP
fnp-3025	24	7	antibody	antibody	NOUN
fnp-3025	24	8	4g8	4g8	NUM
fnp-3025	24	9	to	to	ADP
fnp-3025	24	10	the	the	DET
fnp-3025	24	11	aβ	aβ	NOUN
fnp-3025	24	12	protein	protein	NOUN
fnp-3025	24	13	(	(	PUNCT
fnp-3025	24	14	brown	brown	NOUN
fnp-3025	24	15	)	)	PUNCT
fnp-3025	24	16	along	along	ADP
fnp-3025	24	17	with	with	ADP
fnp-3025	24	18	a	a	DET
fnp-3025	24	19	nissl	nissl	ADJ
fnp-3025	24	20	counterstain	counterstain	NOUN
fnp-3025	24	21	(	(	PUNCT
fnp-3025	24	22	blue	blue	NOUN
fnp-3025	24	23	)	)	PUNCT
fnp-3025	24	24	;	;	PUNCT
fnp-3025	24	25	glial	glial	ADJ
fnp-3025	24	26	nuclei	nucleus	NOUN
fnp-3025	24	27	are	be	AUX
fnp-3025	24	28	visible	visible	ADJ
fnp-3025	24	29	in	in	ADP
fnp-3025	24	30	the	the	DET
fnp-3025	24	31	region	region	NOUN
fnp-3025	24	32	between	between	ADP
fnp-3025	24	33	the	the	DET
fnp-3025	24	34	plaque	plaque	NOUN
fnp-3025	24	35	core	core	NOUN
fnp-3025	24	36	and	and	CCONJ
fnp-3025	24	37	outer	outer	ADJ
fnp-3025	24	38	corona	corona	NOUN
fnp-3025	24	39	,	,	PUNCT
fnp-3025	24	40	and	and	CCONJ
fnp-3025	24	41	within	within	ADP
fnp-3025	24	42	and	and	CCONJ
fnp-3025	24	43	surrounding	surround	VERB
fnp-3025	24	44	the	the	DET
fnp-3025	24	45	corona	corona	NOUN
fnp-3025	24	46	.	.	PUNCT
fnp-3025	25	1	bar	bar	NOUN
fnp-3025	25	2	=	=	SYM
fnp-3025	25	3	20μm	20μm	NOUN
fnp-3025	25	4	for	for	ADP
fnp-3025	25	5	both	both	DET
fnp-3025	25	6	panels	panel	NOUN
fnp-3025	25	7	.	.	PUNCT
fnp-3025	26	1	1.1	1.1	NUM
fnp-3025	26	2	aβ	aβ	NOUN
fnp-3025	26	3	aβ	aβ	NOUN
fnp-3025	26	4	is	be	AUX
fnp-3025	26	5	a	a	DET
fnp-3025	26	6	cleavage	cleavage	NOUN
fnp-3025	26	7	product	product	NOUN
fnp-3025	26	8	of	of	ADP
fnp-3025	26	9	the	the	DET
fnp-3025	26	10	aβ	aβ	NOUN
fnp-3025	26	11	-	-	PUNCT
fnp-3025	26	12	precursor	precursor	NOUN
fnp-3025	26	13	protein	protein	NOUN
fnp-3025	26	14	(	(	PUNCT
fnp-3025	26	15	app	app	PROPN
fnp-3025	26	16	)	)	PUNCT
fnp-3025	26	17	,	,	PUNCT
fnp-3025	26	18	a	a	DET
fnp-3025	26	19	695–770	695–770	NUM
fnp-3025	26	20	amino	amino	ADJ
fnp-3025	26	21	acid	acid	NOUN
fnp-3025	26	22	,	,	PUNCT
fnp-3025	26	23	single	single	ADJ
fnp-3025	26	24	membrane	membrane	NOUN
fnp-3025	26	25	-	-	PUNCT
fnp-3025	26	26	spanning	span	VERB
fnp-3025	26	27	protein	protein	NOUN
fnp-3025	26	28	that	that	PRON
fnp-3025	26	29	is	be	AUX
fnp-3025	26	30	strongly	strongly	ADV
fnp-3025	26	31	expressed	express	VERB
fnp-3025	26	32	in	in	ADP
fnp-3025	26	33	the	the	DET
fnp-3025	26	34	nervous	nervous	ADJ
fnp-3025	26	35	system	system	NOUN
fnp-3025	26	36	[	[	X
fnp-3025	26	37	7	7	NUM
fnp-3025	26	38	,	,	PUNCT
fnp-3025	26	39	8	8	NUM
fnp-3025	26	40	]	]	PUNCT
fnp-3025	26	41	.	.	PUNCT
fnp-3025	27	1	aβ	aβ	PRON
fnp-3025	27	2	is	be	AUX
fnp-3025	27	3	generated	generate	VERB
fnp-3025	27	4	mainly	mainly	ADV
fnp-3025	27	5	in	in	ADP
fnp-3025	27	6	endosomes	endosome	NOUN
fnp-3025	27	7	,	,	PUNCT
fnp-3025	27	8	and	and	CCONJ
fnp-3025	27	9	its	its	PRON
fnp-3025	27	10	release	release	NOUN
fnp-3025	27	11	into	into	ADP
fnp-3025	27	12	the	the	DET
fnp-3025	27	13	extracellular	extracellular	ADJ
fnp-3025	27	14	space	space	NOUN
fnp-3025	27	15	is	be	AUX
fnp-3025	27	16	influenced	influence	VERB
fnp-3025	27	17	by	by	ADP
fnp-3025	27	18	synaptic	synaptic	ADJ
fnp-3025	27	19	activity	activity	NOUN
fnp-3025	28	1	[	[	X
fnp-3025	28	2	9	9	NUM
fnp-3025	28	3	]	]	PUNCT
fnp-3025	28	4	.	.	PUNCT
fnp-3025	29	1	to	to	PART
fnp-3025	29	2	produce	produce	VERB
fnp-3025	29	3	aβ	aβ	NOUN
fnp-3025	29	4	,	,	PUNCT
fnp-3025	29	5	app	app	PROPN
fnp-3025	29	6	is	be	AUX
fnp-3025	29	7	sequentially	sequentially	ADV
fnp-3025	29	8	cleaved	cleave	VERB
fnp-3025	29	9	by	by	ADP
fnp-3025	29	10	the	the	DET
fnp-3025	29	11	enzymes	enzyme	NOUN
fnp-3025	29	12	β	β	NOUN
fnp-3025	29	13	-	-	NOUN
fnp-3025	29	14	secretase	secretase	NOUN
fnp-3025	29	15	[	[	X
fnp-3025	29	16	or	or	CCONJ
fnp-3025	29	17	β	β	NOUN
fnp-3025	29	18	-	-	ADJ
fnp-3025	29	19	amyloid	amyloid	ADJ
fnp-3025	29	20	cleaving	cleave	VERB
fnp-3025	29	21	enzyme	enzyme	NOUN
fnp-3025	29	22	(	(	PUNCT
fnp-3025	29	23	bace	bace	NOUN
fnp-3025	29	24	)	)	PUNCT
fnp-3025	29	25	]	]	PUNCT
fnp-3025	29	26	and	and	CCONJ
fnp-3025	29	27	γ	γ	NOUN
fnp-3025	29	28	-	-	NOUN
fnp-3025	29	29	secretase	secretase	NOUN
fnp-3025	29	30	[	[	X
fnp-3025	29	31	8	8	NUM
fnp-3025	29	32	]	]	PUNCT
fnp-3025	29	33	,	,	PUNCT
fnp-3025	29	34	resulting	result	VERB
fnp-3025	29	35	in	in	ADP
fnp-3025	29	36	aβ	aβ	ADP
fnp-3025	29	37	proteins	protein	NOUN
fnp-3025	29	38	that	that	PRON
fnp-3025	29	39	are	be	AUX
fnp-3025	29	40	most	most	ADV
fnp-3025	29	41	often	often	ADV
fnp-3025	29	42	40	40	NUM
fnp-3025	29	43	or	or	CCONJ
fnp-3025	29	44	42	42	NUM
fnp-3025	29	45	amino	amino	NOUN
fnp-3025	29	46	acids	acid	NOUN
fnp-3025	29	47	in	in	ADP
fnp-3025	29	48	length	length	NOUN
fnp-3025	29	49	(	(	PUNCT
fnp-3025	29	50	‘	'	PUNCT
fnp-3025	29	51	aβ40	aβ40	PROPN
fnp-3025	29	52	’	'	PUNCT
fnp-3025	29	53	and	and	CCONJ
fnp-3025	29	54	‘	'	PUNCT
fnp-3025	29	55	aβ42	aβ42	PROPN
fnp-3025	29	56	’	'	PUNCT
fnp-3025	29	57	)	)	PUNCT
fnp-3025	29	58	,	,	PUNCT
fnp-3025	29	59	although	although	SCONJ
fnp-3025	29	60	many	many	ADJ
fnp-3025	29	61	c	c	NOUN
fnp-3025	29	62	-	-	PUNCT
fnp-3025	29	63	terminally	terminally	ADV
fnp-3025	29	64	and	and	CCONJ
fnp-3025	29	65	n	n	CCONJ
fnp-3025	29	66	-	-	PUNCT
fnp-3025	29	67	terminally	terminally	ADV
fnp-3025	29	68	variant	variant	NOUN
fnp-3025	29	69	and/or	and/or	CCONJ
fnp-3025	29	70	chemically	chemically	ADV
fnp-3025	29	71	modified	modify	VERB
fnp-3025	29	72	aβ	aβ	ADP
fnp-3025	29	73	fragments	fragment	NOUN
fnp-3025	29	74	also	also	ADV
fnp-3025	29	75	occur	occur	VERB
fnp-3025	29	76	[	[	X
fnp-3025	29	77	7	7	NUM
fnp-3025	29	78	,	,	PUNCT
fnp-3025	29	79	10	10	NUM
fnp-3025	29	80	-	-	SYM
fnp-3025	29	81	16	16	NUM
fnp-3025	29	82	]	]	PUNCT
fnp-3025	29	83	.	.	PUNCT
fnp-3025	30	1	different	different	ADJ
fnp-3025	30	2	lengths	length	NOUN
fnp-3025	30	3	of	of	ADP
fnp-3025	30	4	aβ	aβ	NOUN
fnp-3025	30	5	can	can	AUX
fnp-3025	30	6	derive	derive	VERB
fnp-3025	30	7	from	from	ADP
fnp-3025	30	8	their	their	PRON
fnp-3025	30	9	differential	differential	ADJ
fnp-3025	30	10	excision	excision	NOUN
fnp-3025	30	11	from	from	ADP
fnp-3025	30	12	app	app	NOUN
fnp-3025	30	13	by	by	ADP
fnp-3025	30	14	secretases	secretase	NOUN
fnp-3025	30	15	or	or	CCONJ
fnp-3025	30	16	from	from	ADP
fnp-3025	30	17	post	post	ADJ
fnp-3025	30	18	-	-	ADJ
fnp-3025	30	19	translational	translational	ADJ
fnp-3025	30	20	trimming	trimming	NOUN
fnp-3025	30	21	of	of	ADP
fnp-3025	30	22	aβ	aβ	NOUN
fnp-3025	30	23	by	by	ADP
fnp-3025	30	24	exopeptidases	exopeptidase	NOUN
fnp-3025	30	25	[	[	X
fnp-3025	30	26	10	10	NUM
fnp-3025	30	27	]	]	PUNCT
fnp-3025	30	28	.	.	PUNCT
fnp-3025	31	1	potential	potential	ADJ
fnp-3025	31	2	post	post	ADJ
fnp-3025	31	3	-	-	ADJ
fnp-3025	31	4	translational	translational	ADJ
fnp-3025	31	5	chemical	chemical	NOUN
fnp-3025	31	6	modifications	modification	NOUN
fnp-3025	31	7	of	of	ADP
fnp-3025	31	8	aβ	aβ	PRON
fnp-3025	31	9	include	include	VERB
fnp-3025	31	10	pyroglutamylation	pyroglutamylation	NOUN
fnp-3025	31	11	,	,	PUNCT
fnp-3025	31	12	racemization	racemization	NOUN
fnp-3025	31	13	,	,	PUNCT
fnp-3025	31	14	isomerization	isomerization	NOUN
fnp-3025	31	15	,	,	PUNCT
fnp-3025	31	16	oxidation	oxidation	NOUN
fnp-3025	31	17	,	,	PUNCT
fnp-3025	31	18	phosphorylation	phosphorylation	NOUN
fnp-3025	31	19	,	,	PUNCT
fnp-3025	31	20	n	n	CCONJ
fnp-3025	31	21	-	-	PUNCT
fnp-3025	31	22	homocysteinylation	homocysteinylation	NOUN
fnp-3025	31	23	,	,	PUNCT
fnp-3025	31	24	nitration	nitration	NOUN
fnp-3025	31	25	,	,	PUNCT
fnp-3025	31	26	and	and	CCONJ
fnp-3025	31	27	glycosylation	glycosylation	NOUN
fnp-3025	31	28	[	[	X
fnp-3025	31	29	11	11	NUM
fnp-3025	31	30	,	,	PUNCT
fnp-3025	31	31	17	17	NUM
fnp-3025	31	32	-	-	SYM
fnp-3025	31	33	19	19	NUM
fnp-3025	31	34	]	]	PUNCT
fnp-3025	31	35	(	(	PUNCT
fnp-3025	31	36	see	see	VERB
fnp-3025	31	37	also	also	ADV
fnp-3025	31	38	section	section	NOUN
fnp-3025	31	39	7	7	NUM
fnp-3025	31	40	,	,	PUNCT
fnp-3025	31	41	below	below	ADV
fnp-3025	31	42	)	)	PUNCT
fnp-3025	31	43	.	.	PUNCT
fnp-3025	32	1	how	how	SCONJ
fnp-3025	32	2	post	post	ADJ
fnp-3025	32	3	-	-	ADJ
fnp-3025	32	4	translational	translational	ADJ
fnp-3025	32	5	modifications	modification	NOUN
fnp-3025	32	6	influence	influence	VERB
fnp-3025	32	7	the	the	DET
fnp-3025	32	8	process	process	NOUN
fnp-3025	32	9	of	of	ADP
fnp-3025	32	10	protein	protein	NOUN
fnp-3025	32	11	aggregation	aggregation	NOUN
fnp-3025	32	12	in	in	ADP
fnp-3025	32	13	general	general	ADJ
fnp-3025	32	14	remains	remain	VERB
fnp-3025	32	15	poorly	poorly	ADV
fnp-3025	32	16	understood	understand	VERB
fnp-3025	32	17	[	[	X
fnp-3025	32	18	20	20	NUM
fnp-3025	32	19	,	,	PUNCT
fnp-3025	32	20	21	21	NUM
fnp-3025	32	21	]	]	PUNCT
fnp-3025	32	22	.	.	PUNCT
fnp-3025	33	1	aβ40	aβ40	PROPN
fnp-3025	33	2	is	be	AUX
fnp-3025	33	3	the	the	DET
fnp-3025	33	4	isoform	isoform	NOUN
fnp-3025	33	5	of	of	ADP
fnp-3025	33	6	aβ	aβ	PRON
fnp-3025	33	7	that	that	PRON
fnp-3025	33	8	is	be	AUX
fnp-3025	33	9	most	most	ADV
fnp-3025	33	10	abundantly	abundantly	ADV
fnp-3025	33	11	generated	generate	VERB
fnp-3025	33	12	by	by	ADP
fnp-3025	33	13	neurons	neuron	NOUN
fnp-3025	33	14	,	,	PUNCT
fnp-3025	33	15	but	but	CCONJ
fnp-3025	33	16	two	two	NUM
fnp-3025	33	17	c	c	ADJ
fnp-3025	33	18	-	-	PUNCT
fnp-3025	33	19	terminal	terminal	ADJ
fnp-3025	33	20	hydrophobic	hydrophobic	NOUN
fnp-3025	33	21	residues	residue	NOUN
fnp-3025	33	22	in	in	ADP
fnp-3025	33	23	aβ42	aβ42	PROPN
fnp-3025	33	24	augment	augment	VERB
fnp-3025	33	25	its	its	PRON
fnp-3025	33	26	tendency	tendency	NOUN
fnp-3025	33	27	to	to	PART
fnp-3025	33	28	self	self	NOUN
fnp-3025	33	29	-	-	PUNCT
fnp-3025	33	30	assemble	assemble	VERB
fnp-3025	33	31	into	into	ADP
fnp-3025	33	32	amyloid	amyloid	NOUN
fnp-3025	33	33	[	[	X
fnp-3025	33	34	7	7	NUM
fnp-3025	33	35	,	,	PUNCT
fnp-3025	33	36	22	22	NUM
fnp-3025	33	37	]	]	PUNCT
fnp-3025	33	38	.	.	PUNCT
fnp-3025	34	1	as	as	ADP
fnp-3025	34	2	a	a	DET
fnp-3025	34	3	result	result	NOUN
fnp-3025	34	4	,	,	PUNCT
fnp-3025	34	5	more	more	ADJ
fnp-3025	34	6	plaques	plaque	NOUN
fnp-3025	34	7	are	be	AUX
fnp-3025	34	8	immunoreactive	immunoreactive	ADJ
fnp-3025	34	9	for	for	ADP
fnp-3025	34	10	aβ42	aβ42	PROPN
fnp-3025	34	11	than	than	ADP
fnp-3025	34	12	for	for	ADP
fnp-3025	34	13	aβ40	aβ40	PROPN
fnp-3025	34	14	(	(	PUNCT
fnp-3025	34	15	figure	figure	NOUN
fnp-3025	34	16	2	2	NUM
fnp-3025	34	17	)	)	PUNCT
fnp-3025	34	18	,	,	PUNCT
fnp-3025	34	19	although	although	SCONJ
fnp-3025	34	20	the	the	DET
fnp-3025	34	21	relative	relative	ADJ
fnp-3025	34	22	amounts	amount	NOUN
fnp-3025	34	23	of	of	ADP
fnp-3025	34	24	plaques	plaque	NOUN
fnp-3025	34	25	stained	stain	VERB
fnp-3025	34	26	for	for	ADP
fnp-3025	34	27	aβ40	aβ40	PROPN
fnp-3025	34	28	and	and	CCONJ
fnp-3025	34	29	aβ42	aβ42	PROPN
fnp-3025	34	30	vary	vary	VERB
fnp-3025	34	31	.	.	PUNCT
fnp-3025	35	1	figure	figure	NOUN
fnp-3025	35	2	2	2	NUM
fnp-3025	35	3	.	.	PUNCT
fnp-3025	35	4	adjacent	adjacent	ADJ
fnp-3025	35	5	cortical	cortical	ADJ
fnp-3025	35	6	tissue	tissue	NOUN
fnp-3025	35	7	sections	section	NOUN
fnp-3025	35	8	from	from	ADP
fnp-3025	35	9	an	an	DET
fnp-3025	35	10	ad	ad	NOUN
fnp-3025	35	11	patient	patient	NOUN
fnp-3025	35	12	,	,	PUNCT
fnp-3025	35	13	immunostained	immunostaine	VERB
fnp-3025	35	14	with	with	ADP
fnp-3025	35	15	antibodies	antibody	NOUN
fnp-3025	35	16	r398	r398	PROPN
fnp-3025	35	17	to	to	ADP
fnp-3025	35	18	aβ42	aβ42	PROPN
fnp-3025	35	19	(	(	PUNCT
fnp-3025	35	20	top	top	NOUN
fnp-3025	35	21	)	)	PUNCT
fnp-3025	35	22	and	and	CCONJ
fnp-3025	35	23	r361	r361	PROPN
fnp-3025	35	24	to	to	ADP
fnp-3025	35	25	aβ40	aβ40	PROPN
fnp-3025	35	26	(	(	PUNCT
fnp-3025	35	27	bottom	bottom	NOUN
fnp-3025	35	28	)	)	PUNCT
fnp-3025	35	29	.	.	PUNCT
fnp-3025	36	1	two	two	NUM
fnp-3025	36	2	of	of	ADP
fnp-3025	36	3	the	the	DET
fnp-3025	36	4	plaques	plaque	NOUN
fnp-3025	36	5	that	that	PRON
fnp-3025	36	6	are	be	AUX
fnp-3025	36	7	present	present	ADJ
fnp-3025	36	8	in	in	ADP
fnp-3025	36	9	both	both	DET
fnp-3025	36	10	sections	section	NOUN
fnp-3025	36	11	are	be	AUX
fnp-3025	36	12	denoted	denote	VERB
fnp-3025	36	13	by	by	ADP
fnp-3025	36	14	arrows	arrow	NOUN
fnp-3025	36	15	.	.	PUNCT
fnp-3025	37	1	asterisks	asterisk	NOUN
fnp-3025	37	2	mark	mark	VERB
fnp-3025	37	3	a	a	DET
fnp-3025	37	4	blood	blood	NOUN
fnp-3025	37	5	vessel	vessel	NOUN
fnp-3025	37	6	for	for	ADP
fnp-3025	37	7	reference	reference	NOUN
fnp-3025	37	8	.	.	PUNCT
fnp-3025	38	1	bar	bar	NOUN
fnp-3025	38	2	=	=	SYM
fnp-3025	38	3	100μm	100μm	NOUN
fnp-3025	38	4	.	.	PUNCT
fnp-3025	39	1	unlike	unlike	ADP
fnp-3025	39	2	plaques	plaque	NOUN
fnp-3025	39	3	,	,	PUNCT
fnp-3025	39	4	cerebral	cerebral	ADJ
fnp-3025	39	5	aβ	aβ	NOUN
fnp-3025	39	6	-	-	PUNCT
fnp-3025	39	7	amyloid	amyloid	NOUN
fnp-3025	39	8	angiopathy	angiopathy	NOUN
fnp-3025	39	9	(	(	PUNCT
fnp-3025	39	10	aβ	aβ	NOUN
fnp-3025	39	11	-	-	PUNCT
fnp-3025	39	12	caa	caa	NOUN
fnp-3025	39	13	)	)	PUNCT
fnp-3025	39	14	in	in	ADP
fnp-3025	39	15	large	large	ADJ
fnp-3025	39	16	vessels	vessel	NOUN
fnp-3025	39	17	is	be	AUX
fnp-3025	39	18	more	more	ADV
fnp-3025	39	19	consistently	consistently	ADV
fnp-3025	39	20	positive	positive	ADJ
fnp-3025	39	21	for	for	ADP
fnp-3025	39	22	aβ40	aβ40	PROPN
fnp-3025	39	23	,	,	PUNCT
fnp-3025	39	24	though	though	SCONJ
fnp-3025	39	25	aβ42	aβ42	PROPN
fnp-3025	39	26	also	also	ADV
fnp-3025	39	27	is	be	AUX
fnp-3025	39	28	generally	generally	ADV
fnp-3025	39	29	present	present	ADJ
fnp-3025	39	30	[	[	X
fnp-3025	39	31	23	23	NUM
fnp-3025	39	32	]	]	PUNCT
fnp-3025	39	33	.	.	PUNCT
fnp-3025	40	1	the	the	DET
fnp-3025	40	2	staining	stain	VERB
fnp-3025	40	3	patterns	pattern	NOUN
fnp-3025	40	4	of	of	ADP
fnp-3025	40	5	the	the	DET
fnp-3025	40	6	two	two	NUM
fnp-3025	40	7	isoforms	isoform	NOUN
fnp-3025	40	8	differ	differ	VERB
fnp-3025	40	9	in	in	ADP
fnp-3025	40	10	capillary	capillary	ADJ
fnp-3025	40	11	aβ	aβ	NOUN
fnp-3025	40	12	-	-	PUNCT
fnp-3025	40	13	caa	caa	NOUN
fnp-3025	40	14	compared	compare	VERB
fnp-3025	40	15	to	to	ADP
fnp-3025	40	16	large	large	ADJ
fnp-3025	40	17	-	-	PUNCT
fnp-3025	40	18	vessel	vessel	NOUN
fnp-3025	40	19	aβ	aβ	NOUN
fnp-3025	40	20	-	-	PUNCT
fnp-3025	40	21	caa	caa	NOUN
fnp-3025	40	22	[	[	X
fnp-3025	40	23	24	24	NUM
fnp-3025	40	24	,	,	PUNCT
fnp-3025	40	25	25	25	NUM
fnp-3025	40	26	]	]	PUNCT
fnp-3025	40	27	,	,	PUNCT
fnp-3025	40	28	and	and	CCONJ
fnp-3025	40	29	in	in	ADP
fnp-3025	40	30	the	the	DET
fnp-3025	40	31	vessel	vessel	NOUN
fnp-3025	40	32	wall	wall	NOUN
fnp-3025	40	33	compared	compare	VERB
fnp-3025	40	34	to	to	ADP
fnp-3025	40	35	the	the	DET
fnp-3025	40	36	diffuse	diffuse	NOUN
fnp-3025	40	37	aβ	aβ	INTJ
fnp-3025	40	38	that	that	PRON
fnp-3025	40	39	sometimes	sometimes	ADV
fnp-3025	40	40	extends	extend	VERB
fnp-3025	40	41	from	from	ADP
fnp-3025	40	42	the	the	DET
fnp-3025	40	43	wall	wall	NOUN
fnp-3025	40	44	into	into	ADP
fnp-3025	40	45	the	the	DET
fnp-3025	40	46	surrounding	surround	VERB
fnp-3025	40	47	parenchyma	parenchyma	NOUN
fnp-3025	40	48	(	(	PUNCT
fnp-3025	40	49	dyshoric	dyshoric	ADJ
fnp-3025	40	50	amyloid	amyloid	NOUN
fnp-3025	40	51	angiopathy	angiopathy	NOUN
fnp-3025	40	52	)	)	PUNCT
fnp-3025	41	1	[	[	X
fnp-3025	41	2	25	25	NUM
fnp-3025	41	3	,	,	PUNCT
fnp-3025	41	4	26	26	NUM
fnp-3025	41	5	]	]	PUNCT
fnp-3025	41	6	.	.	PUNCT
fnp-3025	42	1	the	the	DET
fnp-3025	42	2	mechanisms	mechanism	NOUN
fnp-3025	42	3	governing	govern	VERB
fnp-3025	42	4	the	the	DET
fnp-3025	42	5	ontogeny	ontogeny	NOUN
fnp-3025	42	6	of	of	ADP
fnp-3025	42	7	plaques	plaque	NOUN
fnp-3025	42	8	and	and	CCONJ
fnp-3025	42	9	aβ	aβ	NOUN
fnp-3025	42	10	-	-	PUNCT
fnp-3025	42	11	caa	caa	NOUN
fnp-3025	42	12	also	also	ADV
fnp-3025	42	13	probably	probably	ADV
fnp-3025	42	14	differ	differ	VERB
fnp-3025	42	15	to	to	ADP
fnp-3025	42	16	some	some	DET
fnp-3025	42	17	extent	extent	NOUN
fnp-3025	42	18	(	(	PUNCT
fnp-3025	42	19	see	see	VERB
fnp-3025	42	20	section	section	NOUN
fnp-3025	42	21	5.3	5.3	NUM
fnp-3025	42	22	)	)	PUNCT
fnp-3025	42	23	.	.	PUNCT
fnp-3025	43	1	in	in	ADP
fnp-3025	43	2	addition	addition	NOUN
fnp-3025	43	3	to	to	ADP
fnp-3025	43	4	plaques	plaque	NOUN
fnp-3025	43	5	and	and	CCONJ
fnp-3025	43	6	amyloid	amyloid	NOUN
fnp-3025	43	7	angiopathy	angiopathy	NOUN
fnp-3025	43	8	,	,	PUNCT
fnp-3025	43	9	aβ	aβ	PRON
fnp-3025	43	10	multimerizes	multimerize	NOUN
fnp-3025	43	11	into	into	ADP
fnp-3025	43	12	a	a	DET
fnp-3025	43	13	range	range	NOUN
fnp-3025	43	14	of	of	ADP
fnp-3025	43	15	oligomeric	oligomeric	ADJ
fnp-3025	43	16	species	specie	NOUN
fnp-3025	43	17	[	[	X
fnp-3025	43	18	27	27	NUM
fnp-3025	43	19	,	,	PUNCT
fnp-3025	43	20	28	28	NUM
fnp-3025	43	21	]	]	PUNCT
fnp-3025	43	22	that	that	PRON
fnp-3025	43	23	can	can	AUX
fnp-3025	43	24	interact	interact	VERB
fnp-3025	43	25	with	with	ADP
fnp-3025	43	26	cells	cell	NOUN
fnp-3025	43	27	and	and	CCONJ
fnp-3025	43	28	impair	impair	VERB
fnp-3025	43	29	brain	brain	NOUN
fnp-3025	43	30	function	function	NOUN
fnp-3025	43	31	[	[	X
fnp-3025	43	32	27	27	NUM
fnp-3025	43	33	,	,	PUNCT
fnp-3025	43	34	29	29	NUM
fnp-3025	43	35	-	-	SYM
fnp-3025	43	36	35	35	NUM
fnp-3025	43	37	]	]	PUNCT
fnp-3025	43	38	.	.	PUNCT
fnp-3025	44	1	oligomers	oligomer	NOUN
fnp-3025	44	2	appear	appear	VERB
fnp-3025	44	3	to	to	PART
fnp-3025	44	4	be	be	AUX
fnp-3025	44	5	an	an	DET
fnp-3025	44	6	important	important	ADJ
fnp-3025	44	7	intermediate	intermediate	ADJ
fnp-3025	44	8	step	step	NOUN
fnp-3025	44	9	in	in	ADP
fnp-3025	44	10	the	the	DET
fnp-3025	44	11	assembly	assembly	NOUN
fnp-3025	44	12	of	of	ADP
fnp-3025	44	13	polymeric	polymeric	ADJ
fnp-3025	44	14	amyloid	amyloid	NOUN
fnp-3025	44	15	of	of	ADP
fnp-3025	44	16	all	all	DET
fnp-3025	44	17	types	type	NOUN
fnp-3025	44	18	[	[	X
fnp-3025	44	19	20	20	NUM
fnp-3025	44	20	]	]	PUNCT
fnp-3025	44	21	.	.	PUNCT
fnp-3025	45	1	comparison	comparison	NOUN
fnp-3025	45	2	of	of	ADP
fnp-3025	45	3	subjects	subject	NOUN
fnp-3025	45	4	expressing	express	VERB
fnp-3025	45	5	ad	ad	NOUN
fnp-3025	45	6	-	-	PUNCT
fnp-3025	45	7	type	type	NOUN
fnp-3025	45	8	dementia	dementia	NOUN
fnp-3025	45	9	to	to	ADP
fnp-3025	45	10	nondemented	nondemente	VERB
fnp-3025	45	11	subjects	subject	NOUN
fnp-3025	45	12	with	with	ADP
fnp-3025	45	13	high	high	ADJ
fnp-3025	45	14	aβ	aβ	NOUN
fnp-3025	45	15	plaque	plaque	NOUN
fnp-3025	45	16	pathology	pathology	NOUN
fnp-3025	45	17	,	,	PUNCT
fnp-3025	45	18	the	the	DET
fnp-3025	45	19	amount	amount	NOUN
fnp-3025	45	20	of	of	ADP
fnp-3025	45	21	oligomeric	oligomeric	ADJ
fnp-3025	45	22	aβ	aβ	NOUN
fnp-3025	45	23	correlates	correlate	VERB
fnp-3025	45	24	more	more	ADV
fnp-3025	45	25	strongly	strongly	ADV
fnp-3025	45	26	with	with	ADP
fnp-3025	45	27	cognitive	cognitive	ADJ
fnp-3025	45	28	decline	decline	NOUN
fnp-3025	45	29	than	than	SCONJ
fnp-3025	45	30	does	do	VERB
fnp-3025	45	31	the	the	DET
fnp-3025	45	32	number	number	NOUN
fnp-3025	45	33	of	of	ADP
fnp-3025	45	34	plaques	plaque	NOUN
fnp-3025	45	35	per	per	ADP
fnp-3025	45	36	se	se	X
fnp-3025	46	1	[	[	X
fnp-3025	46	2	36	36	NUM
fnp-3025	46	3	]	]	PUNCT
fnp-3025	46	4	.	.	PUNCT
fnp-3025	47	1	experimental	experimental	ADJ
fnp-3025	47	2	studies	study	NOUN
fnp-3025	47	3	indicate	indicate	VERB
fnp-3025	47	4	that	that	SCONJ
fnp-3025	47	5	aβ	aβ	DET
fnp-3025	47	6	plaques	plaque	NOUN
fnp-3025	47	7	include	include	VERB
fnp-3025	47	8	abundant	abundant	ADJ
fnp-3025	47	9	oligomers	oligomer	NOUN
fnp-3025	47	10	[	[	X
fnp-3025	47	11	36	36	NUM
fnp-3025	47	12	,	,	PUNCT
fnp-3025	47	13	37	37	NUM
fnp-3025	47	14	]	]	PUNCT
fnp-3025	47	15	,	,	PUNCT
fnp-3025	47	16	and	and	CCONJ
fnp-3025	47	17	that	that	SCONJ
fnp-3025	47	18	some	some	DET
fnp-3025	47	19	plaques	plaque	NOUN
fnp-3025	47	20	shed	shed	VERB
fnp-3025	47	21	toxic	toxic	ADJ
fnp-3025	47	22	oligomers	oligomer	NOUN
fnp-3025	47	23	into	into	ADP
fnp-3025	47	24	the	the	DET
fnp-3025	47	25	surrounding	surround	VERB
fnp-3025	47	26	parenchyma	parenchyma	NOUN
fnp-3025	47	27	[	[	X
fnp-3025	47	28	37	37	NUM
fnp-3025	47	29	-	-	SYM
fnp-3025	47	30	39	39	NUM
fnp-3025	47	31	]	]	PUNCT
fnp-3025	47	32	.	.	PUNCT
fnp-3025	48	1	aβ42	aβ42	NOUN
fnp-3025	48	2	-	-	PUNCT
fnp-3025	48	3	oligomers	oligomer	NOUN
fnp-3025	48	4	have	have	AUX
fnp-3025	48	5	been	be	AUX
fnp-3025	48	6	shown	show	VERB
fnp-3025	48	7	to	to	PART
fnp-3025	48	8	arise	arise	VERB
fnp-3025	48	9	from	from	ADP
fnp-3025	48	10	secondary	secondary	ADJ
fnp-3025	48	11	nucleation	nucleation	NOUN
fnp-3025	48	12	on	on	ADP
fnp-3025	48	13	aβ	aβ	ADJ
fnp-3025	48	14	-	-	PUNCT
fnp-3025	48	15	amyloid	amyloid	NOUN
fnp-3025	48	16	fibrils	fibril	NOUN
fnp-3025	48	17	during	during	ADP
fnp-3025	48	18	protein	protein	NOUN
fnp-3025	48	19	aggregation	aggregation	NOUN
fnp-3025	48	20	,	,	PUNCT
fnp-3025	48	21	directly	directly	ADV
fnp-3025	48	22	linking	link	VERB
fnp-3025	48	23	them	they	PRON
fnp-3025	48	24	to	to	ADP
fnp-3025	48	25	the	the	DET
fnp-3025	48	26	process	process	NOUN
fnp-3025	48	27	of	of	ADP
fnp-3025	48	28	amyloidogenesis	amyloidogenesis	NOUN
fnp-3025	48	29	[	[	X
fnp-3025	48	30	34	34	NUM
fnp-3025	48	31	]	]	PUNCT
fnp-3025	48	32	.	.	PUNCT
fnp-3025	49	1	at	at	ADP
fnp-3025	49	2	least	least	ADJ
fnp-3025	49	3	some	some	PRON
fnp-3025	49	4	aβ	aβ	NOUN
fnp-3025	49	5	-	-	PUNCT
fnp-3025	49	6	oligomers	oligomer	NOUN
fnp-3025	49	7	are	be	AUX
fnp-3025	49	8	particularly	particularly	ADV
fnp-3025	49	9	potent	potent	ADJ
fnp-3025	49	10	seeds	seed	NOUN
fnp-3025	49	11	for	for	ADP
fnp-3025	49	12	the	the	DET
fnp-3025	49	13	formation	formation	NOUN
fnp-3025	49	14	of	of	ADP
fnp-3025	49	15	aβ	aβ	DET
fnp-3025	49	16	plaques	plaque	NOUN
fnp-3025	49	17	[	[	X
fnp-3025	49	18	40	40	NUM
fnp-3025	49	19	,	,	PUNCT
fnp-3025	49	20	41	41	NUM
fnp-3025	49	21	]	]	PUNCT
fnp-3025	49	22	,	,	PUNCT
fnp-3025	49	23	although	although	SCONJ
fnp-3025	49	24	whether	whether	SCONJ
fnp-3025	49	25	there	there	PRON
fnp-3025	49	26	are	be	VERB
fnp-3025	49	27	seed	seed	NOUN
fnp-3025	49	28	-	-	PUNCT
fnp-3025	49	29	active	active	ADJ
fnp-3025	49	30	oligomers	oligomer	NOUN
fnp-3025	49	31	that	that	PRON
fnp-3025	49	32	differ	differ	VERB
fnp-3025	49	33	from	from	ADP
fnp-3025	49	34	toxic	toxic	ADJ
fnp-3025	49	35	oligomers	oligomer	NOUN
fnp-3025	49	36	,	,	PUNCT
fnp-3025	49	37	as	as	SCONJ
fnp-3025	49	38	has	have	AUX
fnp-3025	49	39	been	be	AUX
fnp-3025	49	40	found	find	VERB
fnp-3025	49	41	for	for	ADP
fnp-3025	49	42	prions	prion	NOUN
fnp-3025	49	43	[	[	X
fnp-3025	49	44	42	42	NUM
fnp-3025	49	45	]	]	PUNCT
fnp-3025	49	46	,	,	PUNCT
fnp-3025	49	47	is	be	AUX
fnp-3025	49	48	unknown	unknown	ADJ
fnp-3025	49	49	.	.	PUNCT
fnp-3025	50	1	the	the	DET
fnp-3025	50	2	relationship	relationship	NOUN
fnp-3025	50	3	between	between	ADP
fnp-3025	50	4	aβ	aβ	NOUN
fnp-3025	50	5	-	-	PUNCT
fnp-3025	50	6	oligomers	oligomer	NOUN
fnp-3025	50	7	and	and	CCONJ
fnp-3025	50	8	the	the	DET
fnp-3025	50	9	diverse	diverse	ADJ
fnp-3025	50	10	plaque	plaque	NOUN
fnp-3025	50	11	types	type	NOUN
fnp-3025	50	12	[	[	X
fnp-3025	50	13	31	31	NUM
fnp-3025	50	14	,	,	PUNCT
fnp-3025	50	15	33	33	NUM
fnp-3025	50	16	,	,	PUNCT
fnp-3025	50	17	38	38	NUM
fnp-3025	50	18	]	]	PUNCT
fnp-3025	50	19	in	in	ADP
fnp-3025	50	20	the	the	DET
fnp-3025	50	21	human	human	ADJ
fnp-3025	50	22	brain	brain	NOUN
fnp-3025	50	23	e.g.	e.g.	ADV
fnp-3025	50	24	,	,	PUNCT
fnp-3025	50	25	dense	dense	ADJ
fnp-3025	50	26	-	-	PUNCT
fnp-3025	50	27	core	core	NOUN
fnp-3025	50	28	vs	vs	ADP
fnp-3025	50	29	diffuse	diffuse	NOUN
fnp-3025	50	30	also	also	ADV
fnp-3025	50	31	is	be	AUX
fnp-3025	50	32	an	an	DET
fnp-3025	50	33	issue	issue	NOUN
fnp-3025	50	34	that	that	PRON
fnp-3025	50	35	remains	remains	AUX
fnp-3025	50	36	incompletely	incompletely	ADV
fnp-3025	50	37	defined	define	VERB
fnp-3025	50	38	.	.	PUNCT
fnp-3025	51	1	indeed	indeed	ADV
fnp-3025	51	2	,	,	PUNCT
fnp-3025	51	3	owing	owe	VERB
fnp-3025	51	4	to	to	ADP
fnp-3025	51	5	their	their	PRON
fnp-3025	51	6	dynamicity	dynamicity	NOUN
fnp-3025	51	7	and	and	CCONJ
fnp-3025	51	8	heterogeneity	heterogeneity	NOUN
fnp-3025	51	9	,	,	PUNCT
fnp-3025	51	10	the	the	DET
fnp-3025	51	11	analysis	analysis	NOUN
fnp-3025	51	12	of	of	ADP
fnp-3025	51	13	oligomers	oligomer	NOUN
fnp-3025	51	14	as	as	SCONJ
fnp-3025	51	15	they	they	PRON
fnp-3025	51	16	occur	occur	VERB
fnp-3025	51	17	in	in	ADP
fnp-3025	51	18	living	living	NOUN
fnp-3025	51	19	systems	system	NOUN
fnp-3025	51	20	is	be	AUX
fnp-3025	51	21	technically	technically	ADV
fnp-3025	51	22	challenging	challenge	VERB
fnp-3025	51	23	[	[	X
fnp-3025	51	24	20	20	NUM
fnp-3025	51	25	]	]	PUNCT
fnp-3025	51	26	(	(	PUNCT
fnp-3025	51	27	see	see	AUX
fnp-3025	51	28	also	also	ADV
fnp-3025	51	29	benilova	benilova	VERB
fnp-3025	51	30	et	et	PROPN
fnp-3025	51	31	al	al	PROPN
fnp-3025	51	32	.	.	PUNCT
fnp-3025	52	1	[	[	X
fnp-3025	52	2	43	43	NUM
fnp-3025	52	3	]	]	PUNCT
fnp-3025	52	4	for	for	ADP
fnp-3025	52	5	a	a	DET
fnp-3025	52	6	critique	critique	NOUN
fnp-3025	52	7	of	of	ADP
fnp-3025	52	8	oligomers	oligomer	NOUN
fnp-3025	52	9	as	as	ADP
fnp-3025	52	10	toxic	toxic	ADJ
fnp-3025	52	11	agents	agent	NOUN
fnp-3025	52	12	)	)	PUNCT
fnp-3025	52	13	.	.	PUNCT
fnp-3025	53	1	regardless	regardless	ADV
fnp-3025	53	2	of	of	ADP
fnp-3025	53	3	the	the	DET
fnp-3025	53	4	relative	relative	ADJ
fnp-3025	53	5	contribution	contribution	NOUN
fnp-3025	53	6	of	of	ADP
fnp-3025	53	7	aβ	aβ	NOUN
fnp-3025	53	8	-	-	PUNCT
fnp-3025	53	9	oligomers	oligomer	NOUN
fnp-3025	53	10	and	and	CCONJ
fnp-3025	53	11	amyloid	amyloid	NOUN
fnp-3025	53	12	fibrils	fibril	NOUN
fnp-3025	53	13	to	to	ADP
fnp-3025	53	14	disease	disease	NOUN
fnp-3025	53	15	,	,	PUNCT
fnp-3025	53	16	both	both	PRON
fnp-3025	53	17	of	of	ADP
fnp-3025	53	18	these	these	DET
fnp-3025	53	19	multimeric	multimeric	PROPN
fnp-3025	53	20	states	state	NOUN
fnp-3025	53	21	denote	denote	VERB
fnp-3025	53	22	the	the	DET
fnp-3025	53	23	presence	presence	NOUN
fnp-3025	53	24	of	of	ADP
fnp-3025	53	25	an	an	DET
fnp-3025	53	26	abnormal	abnormal	ADJ
fnp-3025	53	27	condition	condition	NOUN
fnp-3025	53	28	in	in	ADP
fnp-3025	53	29	the	the	DET
fnp-3025	53	30	brain	brain	NOUN
fnp-3025	53	31	,	,	PUNCT
fnp-3025	53	32	i.e.	i.e.	X
fnp-3025	53	33	,	,	PUNCT
fnp-3025	53	34	the	the	DET
fnp-3025	53	35	misfolding	misfolding	NOUN
fnp-3025	53	36	and	and	CCONJ
fnp-3025	53	37	accumulation	accumulation	NOUN
fnp-3025	53	38	of	of	ADP
fnp-3025	53	39	the	the	DET
fnp-3025	53	40	aβ	aβ	NOUN
fnp-3025	53	41	protein	protein	NOUN
fnp-3025	53	42	.	.	PUNCT
fnp-3025	54	1	aβ	aβ	PRON
fnp-3025	54	2	has	have	AUX
fnp-3025	54	3	assumed	assume	VERB
fnp-3025	54	4	a	a	DET
fnp-3025	54	5	prominent	prominent	ADJ
fnp-3025	54	6	position	position	NOUN
fnp-3025	54	7	in	in	ADP
fnp-3025	54	8	alzheimer	alzheimer	PROPN
fnp-3025	54	9	research	research	NOUN
fnp-3025	54	10	because	because	SCONJ
fnp-3025	54	11	all	all	DET
fnp-3025	54	12	identified	identify	VERB
fnp-3025	54	13	risk	risk	NOUN
fnp-3025	54	14	factors	factor	NOUN
fnp-3025	54	15	for	for	ADP
fnp-3025	54	16	ad	ad	NOUN
fnp-3025	54	17	increase	increase	VERB
fnp-3025	54	18	its	its	PRON
fnp-3025	54	19	quantity	quantity	NOUN
fnp-3025	54	20	and/or	and/or	CCONJ
fnp-3025	54	21	tendency	tendency	NOUN
fnp-3025	54	22	to	to	PART
fnp-3025	54	23	aggregate	aggregate	VERB
fnp-3025	54	24	[	[	X
fnp-3025	54	25	33	33	NUM
fnp-3025	54	26	,	,	PUNCT
fnp-3025	54	27	44	44	NUM
fnp-3025	54	28	,	,	PUNCT
fnp-3025	54	29	45	45	NUM
fnp-3025	54	30	]	]	PUNCT
fnp-3025	54	31	.	.	PUNCT
fnp-3025	55	1	most	most	ADV
fnp-3025	55	2	notably	notably	ADV
fnp-3025	55	3	,	,	PUNCT
fnp-3025	55	4	mutations	mutation	NOUN
fnp-3025	55	5	in	in	ADP
fnp-3025	55	6	app	app	NOUN
fnp-3025	55	7	and	and	CCONJ
fnp-3025	55	8	the	the	DET
fnp-3025	55	9	presenilins	presenilin	NOUN
fnp-3025	55	10	(	(	PUNCT
fnp-3025	55	11	components	component	NOUN
fnp-3025	55	12	of	of	ADP
fnp-3025	55	13	the	the	DET
fnp-3025	55	14	γ	γ	PROPN
fnp-3025	55	15	-	-	PUNCT
fnp-3025	55	16	secretase	secretase	ADJ
fnp-3025	55	17	complex	complex	NOUN
fnp-3025	55	18	)	)	PUNCT
fnp-3025	56	1	[	[	X
fnp-3025	56	2	22	22	NUM
fnp-3025	56	3	]	]	PUNCT
fnp-3025	56	4	are	be	AUX
fnp-3025	56	5	the	the	DET
fnp-3025	56	6	only	only	ADV
fnp-3025	56	7	known	know	VERB
fnp-3025	56	8	autosomal	autosomal	ADJ
fnp-3025	56	9	dominant	dominant	ADJ
fnp-3025	56	10	causes	cause	NOUN
fnp-3025	56	11	of	of	ADP
fnp-3025	56	12	ad	ad	NOUN
fnp-3025	56	13	,	,	PUNCT
fnp-3025	56	14	and	and	CCONJ
fnp-3025	56	15	a	a	DET
fnp-3025	56	16	superfluous	superfluous	ADJ
fnp-3025	56	17	app	app	NOUN
fnp-3025	56	18	gene	gene	NOUN
fnp-3025	56	19	due	due	ADP
fnp-3025	56	20	to	to	ADP
fnp-3025	56	21	trisomic	trisomic	ADJ
fnp-3025	56	22	chromosome	chromosome	NOUN
fnp-3025	56	23	21	21	NUM
fnp-3025	56	24	in	in	ADP
fnp-3025	56	25	down	down	ADP
fnp-3025	56	26	syndrome	syndrome	NOUN
fnp-3025	56	27	frequently	frequently	ADV
fnp-3025	56	28	leads	lead	VERB
fnp-3025	56	29	to	to	ADP
fnp-3025	56	30	early	early	ADJ
fnp-3025	56	31	-	-	PUNCT
fnp-3025	56	32	onset	onset	NOUN
fnp-3025	56	33	ad	ad	NOUN
fnp-3025	56	34	[	[	X
fnp-3025	56	35	35	35	NUM
fnp-3025	56	36	,	,	PUNCT
fnp-3025	56	37	46	46	NUM
fnp-3025	56	38	,	,	PUNCT
fnp-3025	56	39	47	47	NUM
fnp-3025	56	40	]	]	PUNCT
fnp-3025	56	41	.	.	PUNCT
fnp-3025	57	1	furthermore	furthermore	ADV
fnp-3025	57	2	,	,	PUNCT
fnp-3025	57	3	a	a	DET
fnp-3025	57	4	rare	rare	ADJ
fnp-3025	57	5	mutation	mutation	NOUN
fnp-3025	57	6	that	that	PRON
fnp-3025	57	7	substitutes	substitute	VERB
fnp-3025	57	8	a	a	DET
fnp-3025	57	9	threonine	threonine	NOUN
fnp-3025	57	10	for	for	ADP
fnp-3025	57	11	alanine	alanine	NOUN
fnp-3025	57	12	(	(	PUNCT
fnp-3025	57	13	a673	a673	PROPN
fnp-3025	57	14	t	t	PROPN
fnp-3025	57	15	)	)	PUNCT
fnp-3025	57	16	at	at	ADP
fnp-3025	57	17	position	position	NOUN
fnp-3025	57	18	2	2	NUM
fnp-3025	57	19	of	of	ADP
fnp-3025	57	20	aβ	aβ	NOUN
fnp-3025	57	21	lowers	lower	VERB
fnp-3025	57	22	both	both	DET
fnp-3025	57	23	the	the	DET
fnp-3025	57	24	production	production	NOUN
fnp-3025	57	25	of	of	ADP
fnp-3025	57	26	aβ	aβ	NOUN
fnp-3025	57	27	[	[	X
fnp-3025	57	28	48	48	NUM
fnp-3025	57	29	]	]	PUNCT
fnp-3025	57	30	and	and	CCONJ
fnp-3025	57	31	its	its	PRON
fnp-3025	57	32	propensity	propensity	NOUN
fnp-3025	57	33	to	to	PART
fnp-3025	57	34	aggregate	aggregate	VERB
fnp-3025	57	35	[	[	X
fnp-3025	57	36	49	49	NUM
fnp-3025	57	37	]	]	PUNCT
fnp-3025	57	38	;	;	PUNCT
fnp-3025	57	39	this	this	DET
fnp-3025	57	40	mutation	mutation	NOUN
fnp-3025	57	41	is	be	AUX
fnp-3025	57	42	associated	associate	VERB
fnp-3025	57	43	with	with	ADP
fnp-3025	57	44	a	a	DET
fnp-3025	57	45	reduced	reduced	ADJ
fnp-3025	57	46	risk	risk	NOUN
fnp-3025	57	47	of	of	ADP
fnp-3025	57	48	manifesting	manifest	VERB
fnp-3025	57	49	ad	ad	NOUN
fnp-3025	57	50	[	[	X
fnp-3025	57	51	48	48	NUM
fnp-3025	57	52	]	]	PUNCT
fnp-3025	57	53	and	and	CCONJ
fnp-3025	57	54	possibly	possibly	ADV
fnp-3025	57	55	parenchymal	parenchymal	ADJ
fnp-3025	57	56	plaques	plaque	NOUN
fnp-3025	57	57	as	as	ADV
fnp-3025	57	58	well	well	ADV
fnp-3025	58	1	[	[	X
fnp-3025	58	2	50	50	NUM
fnp-3025	58	3	]	]	PUNCT
fnp-3025	58	4	.	.	PUNCT
fnp-3025	59	1	contrariwise	contrariwise	ADV
fnp-3025	59	2	,	,	PUNCT
fnp-3025	59	3	when	when	SCONJ
fnp-3025	59	4	a	a	DET
fnp-3025	59	5	valine	valine	NOUN
fnp-3025	59	6	replaces	replace	VERB
fnp-3025	59	7	alanine	alanine	NOUN
fnp-3025	59	8	at	at	ADP
fnp-3025	59	9	position	position	NOUN
fnp-3025	59	10	2	2	NUM
fnp-3025	59	11	(	(	PUNCT
fnp-3025	59	12	a673v	a673v	NOUN
fnp-3025	59	13	)	)	PUNCT
fnp-3025	59	14	,	,	PUNCT
fnp-3025	59	15	aβ	aβ	PRON
fnp-3025	59	16	generation	generation	NOUN
fnp-3025	59	17	is	be	AUX
fnp-3025	59	18	increased	increase	VERB
fnp-3025	59	19	,	,	PUNCT
fnp-3025	59	20	and	and	CCONJ
fnp-3025	59	21	the	the	DET
fnp-3025	59	22	protein	protein	NOUN
fnp-3025	59	23	is	be	AUX
fnp-3025	59	24	more	more	ADV
fnp-3025	59	25	prone	prone	ADJ
fnp-3025	59	26	to	to	PART
fnp-3025	59	27	aggregate	aggregate	VERB
fnp-3025	59	28	,	,	PUNCT
fnp-3025	59	29	resulting	result	VERB
fnp-3025	59	30	in	in	ADP
fnp-3025	59	31	an	an	DET
fnp-3025	59	32	autosomal	autosomal	ADJ
fnp-3025	59	33	recessive	recessive	ADJ
fnp-3025	59	34	form	form	NOUN
fnp-3025	59	35	of	of	ADP
fnp-3025	59	36	ad	ad	NOUN
fnp-3025	59	37	[	[	X
fnp-3025	59	38	51	51	NUM
fnp-3025	59	39	]	]	PUNCT
fnp-3025	59	40	.	.	PUNCT
fnp-3025	60	1	thus	thus	ADV
fnp-3025	60	2	,	,	PUNCT
fnp-3025	60	3	there	there	PRON
fnp-3025	60	4	is	be	VERB
fnp-3025	60	5	little	little	ADJ
fnp-3025	60	6	doubt	doubt	NOUN
fnp-3025	60	7	that	that	SCONJ
fnp-3025	60	8	aβ	aβ	NOUN
fnp-3025	60	9	is	be	AUX
fnp-3025	60	10	intimately	intimately	ADV
fnp-3025	60	11	involved	involve	VERB
fnp-3025	60	12	in	in	ADP
fnp-3025	60	13	the	the	DET
fnp-3025	60	14	pathogenesis	pathogenesis	NOUN
fnp-3025	60	15	of	of	ADP
fnp-3025	60	16	ad	ad	NOUN
fnp-3025	60	17	,	,	PUNCT
fnp-3025	60	18	although	although	SCONJ
fnp-3025	60	19	many	many	ADJ
fnp-3025	60	20	questions	question	NOUN
fnp-3025	60	21	remain	remain	VERB
fnp-3025	60	22	about	about	ADP
fnp-3025	60	23	how	how	SCONJ
fnp-3025	60	24	plaques	plaque	NOUN
fnp-3025	60	25	per	per	X
fnp-3025	60	26	se	se	X
fnp-3025	60	27	participate	participate	VERB
fnp-3025	60	28	in	in	ADP
fnp-3025	60	29	the	the	DET
fnp-3025	60	30	neurodegenerative	neurodegenerative	ADJ
fnp-3025	60	31	process	process	NOUN
fnp-3025	60	32	.	.	PUNCT
fnp-3025	61	1	1.2	1.2	NUM
fnp-3025	61	2	amyloid	amyloid	NOUN
fnp-3025	61	3	a	a	DET
fnp-3025	61	4	persistent	persistent	ADJ
fnp-3025	61	5	source	source	NOUN
fnp-3025	61	6	of	of	ADP
fnp-3025	61	7	misunderstanding	misunderstanding	NOUN
fnp-3025	61	8	regarding	regard	VERB
fnp-3025	61	9	the	the	DET
fnp-3025	61	10	role	role	NOUN
fnp-3025	61	11	of	of	ADP
fnp-3025	61	12	aβ	aβ	PRON
fnp-3025	61	13	in	in	ADP
fnp-3025	61	14	ad	ad	NOUN
fnp-3025	61	15	is	be	AUX
fnp-3025	61	16	the	the	DET
fnp-3025	61	17	common	common	ADJ
fnp-3025	61	18	use	use	NOUN
fnp-3025	61	19	of	of	ADP
fnp-3025	61	20	the	the	DET
fnp-3025	61	21	generic	generic	ADJ
fnp-3025	61	22	term	term	NOUN
fnp-3025	61	23	‘	'	PUNCT
fnp-3025	61	24	amyloid	amyloid	NOUN
fnp-3025	61	25	’	'	PUNCT
fnp-3025	61	26	to	to	PART
fnp-3025	61	27	refer	refer	VERB
fnp-3025	61	28	to	to	ADP
fnp-3025	61	29	the	the	DET
fnp-3025	61	30	protein	protein	NOUN
fnp-3025	61	31	aβ	aβ	NOUN
fnp-3025	61	32	.	.	PUNCT
fnp-3025	62	1	in	in	ADP
fnp-3025	62	2	pathology	pathology	NOUN
fnp-3025	62	3	,	,	PUNCT
fnp-3025	62	4	amyloid	amyloid	NOUN
fnp-3025	62	5	refers	refer	VERB
fnp-3025	62	6	to	to	ADP
fnp-3025	62	7	‘	'	PUNCT
fnp-3025	62	8	mainly	mainly	ADV
fnp-3025	62	9	extracellular	extracellular	ADJ
fnp-3025	62	10	tissue	tissue	NOUN
fnp-3025	62	11	deposits	deposit	NOUN
fnp-3025	62	12	of	of	ADP
fnp-3025	62	13	protein	protein	NOUN
fnp-3025	62	14	fibrils	fibril	NOUN
fnp-3025	62	15	,	,	PUNCT
fnp-3025	62	16	recognized	recognize	VERB
fnp-3025	62	17	by	by	ADP
fnp-3025	62	18	certain	certain	ADJ
fnp-3025	62	19	properties	property	NOUN
fnp-3025	62	20	,	,	PUNCT
fnp-3025	62	21	such	such	ADJ
fnp-3025	62	22	as	as	ADP
fnp-3025	62	23	green	green	ADJ
fnp-3025	62	24	-	-	PUNCT
fnp-3025	62	25	yellow	yellow	NOUN
fnp-3025	62	26	birefringence	birefringence	NOUN
fnp-3025	62	27	after	after	ADP
fnp-3025	62	28	staining	stain	VERB
fnp-3025	62	29	with	with	ADP
fnp-3025	62	30	congo	congo	NOUN
fnp-3025	62	31	red	red	ADJ
fnp-3025	62	32	’	'	PUNCT
fnp-3025	63	1	[	[	X
fnp-3025	63	2	6	6	NUM
fnp-3025	63	3	]	]	PUNCT
fnp-3025	63	4	(	(	PUNCT
fnp-3025	63	5	for	for	ADP
fnp-3025	63	6	historical	historical	ADJ
fnp-3025	63	7	considerations	consideration	NOUN
fnp-3025	63	8	of	of	ADP
fnp-3025	63	9	amyloid	amyloid	NOUN
fnp-3025	63	10	,	,	PUNCT
fnp-3025	63	11	see	see	VERB
fnp-3025	63	12	[	[	X
fnp-3025	63	13	20	20	NUM
fnp-3025	63	14	,	,	PUNCT
fnp-3025	63	15	52	52	NUM
fnp-3025	63	16	-	-	SYM
fnp-3025	63	17	55	55	NUM
fnp-3025	63	18	]	]	PUNCT
fnp-3025	63	19	,	,	PUNCT
fnp-3025	63	20	and	and	CCONJ
fnp-3025	63	21	for	for	ADP
fnp-3025	63	22	more	more	ADJ
fnp-3025	63	23	on	on	ADP
fnp-3025	63	24	the	the	DET
fnp-3025	63	25	definition	definition	NOUN
fnp-3025	63	26	of	of	ADP
fnp-3025	63	27	amyloid	amyloid	NOUN
fnp-3025	63	28	see	see	VERB
fnp-3025	63	29	[	[	X
fnp-3025	63	30	20	20	NUM
fnp-3025	63	31	,	,	PUNCT
fnp-3025	63	32	56	56	NUM
fnp-3025	63	33	,	,	PUNCT
fnp-3025	63	34	57	57	NUM
fnp-3025	63	35	]	]	PUNCT
fnp-3025	63	36	.	.	PUNCT
fnp-3025	64	1	amyloid	amyloid	NOUN
fnp-3025	64	2	can	can	AUX
fnp-3025	64	3	arise	arise	VERB
fnp-3025	64	4	from	from	ADP
fnp-3025	64	5	over	over	ADP
fnp-3025	64	6	30	30	NUM
fnp-3025	64	7	different	different	ADJ
fnp-3025	64	8	proteins	protein	NOUN
fnp-3025	64	9	in	in	ADP
fnp-3025	64	10	various	various	ADJ
fnp-3025	64	11	parts	part	NOUN
fnp-3025	64	12	of	of	ADP
fnp-3025	64	13	the	the	DET
fnp-3025	64	14	body	body	NOUN
fnp-3025	64	15	in	in	ADP
fnp-3025	64	16	different	different	ADJ
fnp-3025	64	17	human	human	ADJ
fnp-3025	64	18	diseases	disease	NOUN
fnp-3025	64	19	[	[	X
fnp-3025	64	20	6	6	NUM
fnp-3025	64	21	,	,	PUNCT
fnp-3025	64	22	58	58	NUM
fnp-3025	64	23	]	]	PUNCT
fnp-3025	64	24	.	.	PUNCT
fnp-3025	65	1	hence	hence	ADV
fnp-3025	65	2	,	,	PUNCT
fnp-3025	65	3	‘	'	PUNCT
fnp-3025	65	4	aβ	aβ	X
fnp-3025	65	5	’	'	PUNCT
fnp-3025	65	6	the	the	DET
fnp-3025	65	7	molecule	molecule	NOUN
fnp-3025	65	8	and	and	CCONJ
fnp-3025	65	9	‘	'	PUNCT
fnp-3025	65	10	amyloid	amyloid	NOUN
fnp-3025	65	11	’	'	PUNCT
fnp-3025	65	12	the	the	DET
fnp-3025	65	13	fibrillar	fibrillar	ADJ
fnp-3025	65	14	mass	mass	NOUN
fnp-3025	65	15	are	be	AUX
fnp-3025	65	16	not	not	PART
fnp-3025	65	17	synonymous	synonymous	ADJ
fnp-3025	65	18	.	.	PUNCT
fnp-3025	66	1	aβ	aβ	PRON
fnp-3025	66	2	refers	refer	VERB
fnp-3025	66	3	exclusively	exclusively	ADV
fnp-3025	66	4	to	to	ADP
fnp-3025	66	5	the	the	DET
fnp-3025	66	6	protein	protein	NOUN
fnp-3025	66	7	that	that	PRON
fnp-3025	66	8	,	,	PUNCT
fnp-3025	66	9	when	when	SCONJ
fnp-3025	66	10	aggregated	aggregate	VERB
fnp-3025	66	11	into	into	ADP
fnp-3025	66	12	distinctive	distinctive	ADJ
fnp-3025	66	13	fibrils	fibril	NOUN
fnp-3025	66	14	,	,	PUNCT
fnp-3025	66	15	constitutes	constitute	VERB
fnp-3025	66	16	the	the	DET
fnp-3025	66	17	specific	specific	ADJ
fnp-3025	66	18	type	type	NOUN
fnp-3025	66	19	of	of	ADP
fnp-3025	66	20	amyloid	amyloid	NOUN
fnp-3025	66	21	that	that	PRON
fnp-3025	66	22	most	most	ADV
fnp-3025	66	23	commonly	commonly	ADV
fnp-3025	66	24	accumulates	accumulate	VERB
fnp-3025	66	25	in	in	ADP
fnp-3025	66	26	the	the	DET
fnp-3025	66	27	aging	age	VERB
fnp-3025	66	28	brain	brain	NOUN
fnp-3025	66	29	.	.	PUNCT
fnp-3025	67	1	the	the	DET
fnp-3025	67	2	formation	formation	NOUN
fnp-3025	67	3	of	of	ADP
fnp-3025	67	4	amyloid	amyloid	NOUN
fnp-3025	67	5	involves	involve	VERB
fnp-3025	67	6	the	the	DET
fnp-3025	67	7	misfolding	misfolding	ADJ
fnp-3025	67	8	and	and	CCONJ
fnp-3025	67	9	self	self	NOUN
fnp-3025	67	10	-	-	PUNCT
fnp-3025	67	11	assembly	assembly	NOUN
fnp-3025	67	12	of	of	ADP
fnp-3025	67	13	a	a	DET
fnp-3025	67	14	particular	particular	ADJ
fnp-3025	67	15	protein	protein	NOUN
fnp-3025	67	16	into	into	ADP
fnp-3025	67	17	filamentous	filamentous	ADJ
fnp-3025	67	18	structures	structure	NOUN
fnp-3025	67	19	with	with	ADP
fnp-3025	67	20	a	a	DET
fnp-3025	67	21	distinctive	distinctive	ADJ
fnp-3025	67	22	cross	cross	NOUN
fnp-3025	67	23	-	-	ADJ
fnp-3025	67	24	β	β	ADJ
fnp-3025	67	25	architecture	architecture	NOUN
fnp-3025	67	26	that	that	PRON
fnp-3025	67	27	is	be	AUX
fnp-3025	67	28	stabilized	stabilize	VERB
fnp-3025	67	29	by	by	ADP
fnp-3025	67	30	a	a	DET
fnp-3025	67	31	‘	'	PUNCT
fnp-3025	67	32	steric	steric	ADJ
fnp-3025	67	33	zipper	zipper	NOUN
fnp-3025	67	34	’	'	PUNCT
fnp-3025	67	35	molecular	molecular	ADJ
fnp-3025	67	36	motif	motif	NOUN
fnp-3025	67	37	[	[	X
fnp-3025	67	38	20	20	NUM
fnp-3025	67	39	,	,	PUNCT
fnp-3025	67	40	59	59	NUM
fnp-3025	67	41	]	]	PUNCT
fnp-3025	67	42	.	.	PUNCT
fnp-3025	68	1	the	the	DET
fnp-3025	68	2	misfolded	misfolded	ADJ
fnp-3025	68	3	protein	protein	NOUN
fnp-3025	68	4	has	have	VERB
fnp-3025	68	5	two	two	NUM
fnp-3025	68	6	notable	notable	ADJ
fnp-3025	68	7	characteristics	characteristic	NOUN
fnp-3025	68	8	that	that	PRON
fnp-3025	68	9	contribute	contribute	VERB
fnp-3025	68	10	to	to	ADP
fnp-3025	68	11	its	its	PRON
fnp-3025	68	12	amyloidogenicity	amyloidogenicity	NOUN
fnp-3025	68	13	:	:	PUNCT
fnp-3025	68	14	1	1	X
fnp-3025	68	15	)	)	PUNCT
fnp-3025	68	16	it	it	PRON
fnp-3025	68	17	compels	compel	VERB
fnp-3025	68	18	unfolded	unfold	VERB
fnp-3025	68	19	molecules	molecule	NOUN
fnp-3025	68	20	of	of	ADP
fnp-3025	68	21	the	the	DET
fnp-3025	68	22	same	same	ADJ
fnp-3025	68	23	protein	protein	NOUN
fnp-3025	68	24	to	to	PART
fnp-3025	68	25	similarly	similarly	ADV
fnp-3025	68	26	misfold	misfold	VERB
fnp-3025	68	27	by	by	ADP
fnp-3025	68	28	means	mean	NOUN
fnp-3025	68	29	of	of	ADP
fnp-3025	68	30	permissive	permissive	ADJ
fnp-3025	68	31	templating	templating	NOUN
fnp-3025	68	32	[	[	X
fnp-3025	68	33	60	60	NUM
fnp-3025	68	34	]	]	PUNCT
fnp-3025	68	35	;	;	PUNCT
fnp-3025	68	36	and	and	CCONJ
fnp-3025	68	37	2	2	X
fnp-3025	68	38	)	)	PUNCT
fnp-3025	68	39	the	the	DET
fnp-3025	68	40	β	β	NOUN
fnp-3025	68	41	-	-	NOUN
fnp-3025	68	42	sheets	sheet	NOUN
fnp-3025	68	43	in	in	ADP
fnp-3025	68	44	separate	separate	ADJ
fnp-3025	68	45	molecules	molecule	NOUN
fnp-3025	68	46	hydrogen	hydrogen	NOUN
fnp-3025	68	47	-	-	PUNCT
fnp-3025	68	48	bond	bond	NOUN
fnp-3025	68	49	to	to	ADP
fnp-3025	68	50	one	one	NUM
fnp-3025	68	51	another	another	DET
fnp-3025	68	52	to	to	PART
fnp-3025	68	53	form	form	VERB
fnp-3025	68	54	stable	stable	ADJ
fnp-3025	68	55	,	,	PUNCT
fnp-3025	68	56	filiform	filiform	NOUN
fnp-3025	68	57	polymers	polymer	NOUN
fnp-3025	68	58	with	with	ADP
fnp-3025	68	59	the	the	DET
fnp-3025	68	60	β	β	NOUN
fnp-3025	68	61	-	-	PUNCT
fnp-3025	68	62	sheets	sheet	NOUN
fnp-3025	68	63	oriented	orient	VERB
fnp-3025	68	64	perpendicular	perpendicular	NOUN
fnp-3025	68	65	to	to	ADP
fnp-3025	68	66	the	the	DET
fnp-3025	68	67	long	long	ADJ
fnp-3025	68	68	axis	axis	NOUN
fnp-3025	68	69	of	of	ADP
fnp-3025	68	70	the	the	DET
fnp-3025	68	71	polymer	polymer	NOUN
fnp-3025	68	72	[	[	X
fnp-3025	68	73	59	59	NUM
fnp-3025	68	74	]	]	PUNCT
fnp-3025	68	75	.	.	PUNCT
fnp-3025	69	1	in	in	ADP
fnp-3025	69	2	this	this	DET
fnp-3025	69	3	way	way	NOUN
fnp-3025	69	4	,	,	PUNCT
fnp-3025	69	5	the	the	DET
fnp-3025	69	6	misshapen	misshapen	ADJ
fnp-3025	69	7	proteins	protein	NOUN
fnp-3025	69	8	both	both	CCONJ
fnp-3025	69	9	corrupt	corrupt	ADJ
fnp-3025	69	10	and	and	CCONJ
fnp-3025	69	11	capture	capture	VERB
fnp-3025	69	12	like	like	ADP
fnp-3025	69	13	proteins	protein	NOUN
fnp-3025	69	14	,	,	PUNCT
fnp-3025	69	15	which	which	PRON
fnp-3025	69	16	stack	stack	VERB
fnp-3025	69	17	into	into	ADP
fnp-3025	69	18	protofilaments	protofilament	NOUN
fnp-3025	69	19	that	that	PRON
fnp-3025	69	20	wind	wind	VERB
fnp-3025	69	21	together	together	ADV
fnp-3025	69	22	to	to	PART
fnp-3025	69	23	build	build	VERB
fnp-3025	69	24	long	long	ADJ
fnp-3025	69	25	,	,	PUNCT
fnp-3025	69	26	non	non	ADJ
fnp-3025	69	27	-	-	ADJ
fnp-3025	69	28	branching	branching	ADJ
fnp-3025	69	29	fibrils	fibril	NOUN
fnp-3025	69	30	that	that	SCONJ
fnp-3025	69	31	typically	typically	ADV
fnp-3025	69	32	range	range	VERB
fnp-3025	69	33	from	from	ADP
fnp-3025	69	34	~6	~6	NUM
fnp-3025	69	35	to	to	ADP
fnp-3025	69	36	13	13	NUM
fnp-3025	69	37	nm	nm	NOUN
fnp-3025	69	38	in	in	ADP
fnp-3025	69	39	diameter	diameter	NOUN
fnp-3025	69	40	[	[	X
fnp-3025	69	41	54	54	NUM
fnp-3025	69	42	]	]	PUNCT
fnp-3025	69	43	.	.	PUNCT
fnp-3025	70	1	these	these	DET
fnp-3025	70	2	fibrils	fibril	NOUN
fnp-3025	70	3	are	be	AUX
fnp-3025	70	4	characteristic	characteristic	ADJ
fnp-3025	70	5	of	of	ADP
fnp-3025	70	6	amyloid	amyloid	NOUN
fnp-3025	70	7	in	in	ADP
fnp-3025	70	8	general	general	ADJ
fnp-3025	70	9	[	[	X
fnp-3025	70	10	6	6	NUM
fnp-3025	70	11	]	]	PUNCT
fnp-3025	70	12	.	.	PUNCT
fnp-3025	71	1	despite	despite	SCONJ
fnp-3025	71	2	their	their	PRON
fnp-3025	71	3	shared	share	VERB
fnp-3025	71	4	cross	cross	NOUN
fnp-3025	71	5	-	-	NOUN
fnp-3025	71	6	β	β	ADJ
fnp-3025	71	7	backbone	backbone	NOUN
fnp-3025	71	8	and	and	CCONJ
fnp-3025	71	9	similar	similar	ADJ
fnp-3025	71	10	appearance	appearance	NOUN
fnp-3025	71	11	by	by	ADP
fnp-3025	71	12	conventional	conventional	ADJ
fnp-3025	71	13	transmission	transmission	NOUN
fnp-3025	71	14	electron	electron	NOUN
fnp-3025	71	15	microscopy	microscopy	NOUN
fnp-3025	71	16	,	,	PUNCT
fnp-3025	71	17	however	however	ADV
fnp-3025	71	18	,	,	PUNCT
fnp-3025	71	19	amyloid	amyloid	NOUN
fnp-3025	71	20	fibrils	fibril	NOUN
fnp-3025	71	21	are	be	AUX
fnp-3025	71	22	polymorphic	polymorphic	ADJ
fnp-3025	71	23	at	at	ADP
fnp-3025	71	24	the	the	DET
fnp-3025	71	25	molecular	molecular	ADJ
fnp-3025	71	26	level	level	NOUN
fnp-3025	71	27	[	[	X
fnp-3025	71	28	20	20	NUM
fnp-3025	71	29	,	,	PUNCT
fnp-3025	71	30	61	61	NUM
fnp-3025	71	31	-	-	SYM
fnp-3025	71	32	68	68	NUM
fnp-3025	71	33	]	]	PUNCT
fnp-3025	71	34	.	.	PUNCT
fnp-3025	72	1	although	although	SCONJ
fnp-3025	72	2	amyloid	amyloid	NOUN
fnp-3025	72	3	was	be	AUX
fnp-3025	72	4	long	long	ADV
fnp-3025	72	5	defined	define	VERB
fnp-3025	72	6	as	as	ADP
fnp-3025	72	7	an	an	DET
fnp-3025	72	8	exclusively	exclusively	ADV
fnp-3025	72	9	extracellular	extracellular	ADJ
fnp-3025	72	10	substance	substance	NOUN
fnp-3025	72	11	[	[	X
fnp-3025	72	12	69	69	NUM
fnp-3025	72	13	-	-	SYM
fnp-3025	72	14	71	71	NUM
fnp-3025	72	15	]	]	PUNCT
fnp-3025	72	16	,	,	PUNCT
fnp-3025	72	17	it	it	PRON
fnp-3025	72	18	is	be	AUX
fnp-3025	72	19	now	now	ADV
fnp-3025	72	20	recognized	recognize	VERB
fnp-3025	72	21	to	to	PART
fnp-3025	72	22	occur	occur	VERB
fnp-3025	72	23	intracellularly	intracellularly	ADV
fnp-3025	72	24	as	as	ADP
fnp-3025	72	25	certain	certain	ADJ
fnp-3025	72	26	types	type	NOUN
fnp-3025	72	27	of	of	ADP
fnp-3025	72	28	inclusion	inclusion	NOUN
fnp-3025	72	29	[	[	X
fnp-3025	72	30	6	6	NUM
fnp-3025	72	31	,	,	PUNCT
fnp-3025	72	32	20	20	NUM
fnp-3025	72	33	]	]	PUNCT
fnp-3025	72	34	.	.	PUNCT
fnp-3025	73	1	the	the	DET
fnp-3025	73	2	tau	tau	PROPN
fnp-3025	73	3	protein	protein	NOUN
fnp-3025	73	4	that	that	PRON
fnp-3025	73	5	polymerizes	polymerize	VERB
fnp-3025	73	6	into	into	ADP
fnp-3025	73	7	neurofibrillary	neurofibrillary	ADJ
fnp-3025	73	8	tangles	tangle	NOUN
fnp-3025	73	9	the	the	DET
fnp-3025	73	10	second	second	ADJ
fnp-3025	73	11	mandatory	mandatory	ADJ
fnp-3025	73	12	pathologic	pathologic	ADJ
fnp-3025	73	13	hallmark	hallmark	NOUN
fnp-3025	73	14	of	of	ADP
fnp-3025	73	15	ad	ad	NOUN
fnp-3025	73	16	(	(	PUNCT
fnp-3025	73	17	figure	figure	NOUN
fnp-3025	73	18	3	3	NUM
fnp-3025	73	19	)	)	PUNCT
fnp-3025	73	20	has	have	VERB
fnp-3025	73	21	attributes	attribute	NOUN
fnp-3025	73	22	of	of	ADP
fnp-3025	73	23	amyloid	amyloid	NOUN
fnp-3025	73	24	[	[	X
fnp-3025	73	25	72	72	NUM
fnp-3025	73	26	]	]	PUNCT
fnp-3025	73	27	.	.	PUNCT
fnp-3025	74	1	thus	thus	ADV
fnp-3025	74	2	,	,	PUNCT
fnp-3025	74	3	the	the	DET
fnp-3025	74	4	two	two	NUM
fnp-3025	74	5	lesions	lesion	NOUN
fnp-3025	74	6	that	that	PRON
fnp-3025	74	7	characterize	characterize	VERB
fnp-3025	74	8	ad	ad	NOUN
fnp-3025	74	9	pathologically	pathologically	ADV
fnp-3025	74	10	plaques	plaque	NOUN
fnp-3025	74	11	and	and	CCONJ
fnp-3025	74	12	tangles	tangle	NOUN
fnp-3025	74	13	arise	arise	VERB
fnp-3025	74	14	from	from	ADP
fnp-3025	74	15	two	two	NUM
fnp-3025	74	16	different	different	ADJ
fnp-3025	74	17	proteins	protein	NOUN
fnp-3025	74	18	aβ	aβ	NOUN
fnp-3025	74	19	and	and	CCONJ
fnp-3025	74	20	tau	tau	PROPN
fnp-3025	74	21	both	both	PRON
fnp-3025	74	22	of	of	ADP
fnp-3025	74	23	which	which	PRON
fnp-3025	74	24	can	can	AUX
fnp-3025	74	25	misfold	misfold	VERB
fnp-3025	74	26	and	and	CCONJ
fnp-3025	74	27	self	self	NOUN
fnp-3025	74	28	-	-	PUNCT
fnp-3025	74	29	assemble	assemble	NOUN
fnp-3025	74	30	into	into	ADP
fnp-3025	74	31	amyloid	amyloid	NOUN
fnp-3025	74	32	.	.	PUNCT
fnp-3025	75	1	figure	figure	NOUN
fnp-3025	75	2	3	3	NUM
fnp-3025	75	3	.	.	PUNCT
fnp-3025	76	1	an	an	DET
fnp-3025	76	2	aβ	aβ	NOUN
fnp-3025	76	3	plaque	plaque	NOUN
fnp-3025	76	4	(	(	PUNCT
fnp-3025	76	5	brown	brown	NOUN
fnp-3025	76	6	)	)	PUNCT
fnp-3025	76	7	alongside	alongside	ADP
fnp-3025	76	8	intracellular	intracellular	ADJ
fnp-3025	76	9	tau	tau	PROPN
fnp-3025	76	10	tangles	tangle	NOUN
fnp-3025	76	11	(	(	PUNCT
fnp-3025	76	12	purple	purple	ADJ
fnp-3025	76	13	)	)	PUNCT
fnp-3025	76	14	in	in	ADP
fnp-3025	76	15	the	the	DET
fnp-3025	76	16	cortex	cortex	NOUN
fnp-3025	76	17	of	of	ADP
fnp-3025	76	18	an	an	DET
fnp-3025	76	19	ad	ad	NOUN
fnp-3025	76	20	patient	patient	NOUN
fnp-3025	76	21	.	.	PUNCT
fnp-3025	77	1	combined	combine	VERB
fnp-3025	77	2	polyclonal	polyclonal	ADJ
fnp-3025	77	3	antibodies	antibodie	VERB
fnp-3025	77	4	r398+r361	r398+r361	NOUN
fnp-3025	77	5	to	to	ADP
fnp-3025	77	6	aβ40	aβ40	PROPN
fnp-3025	77	7	+	+	PROPN
fnp-3025	77	8	42	42	NUM
fnp-3025	77	9	plus	plus	CCONJ
fnp-3025	77	10	monoclonal	monoclonal	NOUN
fnp-3025	77	11	antibody	antibody	NOUN
fnp-3025	77	12	cp13	cp13	PROPN
fnp-3025	77	13	to	to	PART
fnp-3025	77	14	hyperphosphorylated	hyperphosphorylated	VERB
fnp-3025	77	15	tau	tau	PROPN
fnp-3025	77	16	.	.	PUNCT
fnp-3025	78	1	bar	bar	NOUN
fnp-3025	78	2	=	=	PUNCT
fnp-3025	78	3	20μm	20μm	NOUN
fnp-3025	78	4	.	.	PUNCT
fnp-3025	79	1	despite	despite	SCONJ
fnp-3025	79	2	genetic	genetic	ADJ
fnp-3025	79	3	,	,	PUNCT
fnp-3025	79	4	biomarker	biomarker	NOUN
fnp-3025	79	5	and	and	CCONJ
fnp-3025	79	6	pathologic	pathologic	ADJ
fnp-3025	79	7	findings	finding	NOUN
fnp-3025	79	8	implicating	implicate	VERB
fnp-3025	79	9	aberrant	aberrant	ADJ
fnp-3025	79	10	aβ	aβ	NOUN
fnp-3025	79	11	in	in	ADP
fnp-3025	79	12	the	the	DET
fnp-3025	79	13	initiation	initiation	NOUN
fnp-3025	79	14	of	of	ADP
fnp-3025	79	15	ad	ad	NOUN
fnp-3025	79	16	[	[	X
fnp-3025	79	17	9	9	NUM
fnp-3025	79	18	,	,	PUNCT
fnp-3025	79	19	33	33	NUM
fnp-3025	79	20	,	,	PUNCT
fnp-3025	79	21	44	44	NUM
fnp-3025	79	22	]	]	PUNCT
fnp-3025	79	23	,	,	PUNCT
fnp-3025	79	24	tauopathy	tauopathy	NOUN
fnp-3025	79	25	is	be	AUX
fnp-3025	79	26	more	more	ADV
fnp-3025	79	27	strongly	strongly	ADV
fnp-3025	79	28	correlated	correlate	VERB
fnp-3025	79	29	with	with	ADP
fnp-3025	79	30	cognitive	cognitive	ADJ
fnp-3025	79	31	decline	decline	NOUN
fnp-3025	79	32	than	than	SCONJ
fnp-3025	79	33	are	be	AUX
fnp-3025	79	34	plaques	plaque	NOUN
fnp-3025	79	35	[	[	X
fnp-3025	79	36	73	73	NUM
fnp-3025	79	37	-	-	SYM
fnp-3025	79	38	78	78	NUM
fnp-3025	79	39	]	]	PUNCT
fnp-3025	79	40	.	.	PUNCT
fnp-3025	80	1	in	in	ADP
fnp-3025	80	2	the	the	DET
fnp-3025	80	3	forebrain	forebrain	NOUN
fnp-3025	80	4	,	,	PUNCT
fnp-3025	80	5	tangles	tangle	NOUN
fnp-3025	80	6	first	first	ADV
fnp-3025	80	7	appear	appear	VERB
fnp-3025	80	8	in	in	ADP
fnp-3025	80	9	the	the	DET
fnp-3025	80	10	medial	medial	ADJ
fnp-3025	80	11	temporal	temporal	ADJ
fnp-3025	80	12	lobe	lobe	NOUN
fnp-3025	80	13	[	[	X
fnp-3025	80	14	79	79	NUM
fnp-3025	80	15	,	,	PUNCT
fnp-3025	80	16	80	80	NUM
fnp-3025	80	17	]	]	PUNCT
fnp-3025	80	18	,	,	PUNCT
fnp-3025	80	19	but	but	CCONJ
fnp-3025	80	20	the	the	DET
fnp-3025	80	21	dementia	dementia	NOUN
fnp-3025	80	22	of	of	ADP
fnp-3025	80	23	ad	ad	NOUN
fnp-3025	80	24	is	be	AUX
fnp-3025	80	25	fully	fully	ADV
fnp-3025	80	26	apparent	apparent	ADJ
fnp-3025	80	27	only	only	ADV
fnp-3025	80	28	when	when	SCONJ
fnp-3025	80	29	tauopathy	tauopathy	ADJ
fnp-3025	80	30	becomes	become	VERB
fnp-3025	80	31	severe	severe	ADJ
fnp-3025	80	32	in	in	ADP
fnp-3025	80	33	much	much	ADJ
fnp-3025	80	34	of	of	ADP
fnp-3025	80	35	the	the	DET
fnp-3025	80	36	neocortex	neocortex	NOUN
fnp-3025	81	1	[	[	X
fnp-3025	81	2	1	1	NUM
fnp-3025	81	3	,	,	PUNCT
fnp-3025	81	4	81	81	NUM
fnp-3025	81	5	]	]	PUNCT
fnp-3025	81	6	,	,	PUNCT
fnp-3025	81	7	a	a	DET
fnp-3025	81	8	process	process	NOUN
fnp-3025	81	9	that	that	PRON
fnp-3025	81	10	is	be	AUX
fnp-3025	81	11	facilitated	facilitate	VERB
fnp-3025	81	12	by	by	ADP
fnp-3025	81	13	the	the	DET
fnp-3025	81	14	presence	presence	NOUN
fnp-3025	81	15	of	of	ADP
fnp-3025	81	16	aβ	aβ	DET
fnp-3025	81	17	pathology	pathology	NOUN
fnp-3025	81	18	[	[	X
fnp-3025	81	19	9	9	NUM
fnp-3025	81	20	]	]	PUNCT
fnp-3025	81	21	(	(	PUNCT
fnp-3025	81	22	see	see	VERB
fnp-3025	81	23	also	also	ADV
fnp-3025	81	24	[	[	X
fnp-3025	81	25	82	82	NUM
fnp-3025	81	26	]	]	NUM
fnp-3025	81	27	)	)	PUNCT
fnp-3025	81	28	.	.	PUNCT
fnp-3025	82	1	the	the	DET
fnp-3025	82	2	precise	precise	ADJ
fnp-3025	82	3	nature	nature	NOUN
fnp-3025	82	4	of	of	ADP
fnp-3025	82	5	the	the	DET
fnp-3025	82	6	mechanistic	mechanistic	PROPN
fnp-3025	82	7	link	link	NOUN
fnp-3025	82	8	between	between	ADP
fnp-3025	82	9	aβ	aβ	NOUN
fnp-3025	82	10	-	-	PUNCT
fnp-3025	82	11	proteopathy	proteopathy	ADJ
fnp-3025	82	12	and	and	CCONJ
fnp-3025	82	13	tauopathy	tauopathy	NOUN
fnp-3025	82	14	in	in	ADP
fnp-3025	82	15	ad	ad	NOUN
fnp-3025	82	16	,	,	PUNCT
fnp-3025	82	17	however	however	ADV
fnp-3025	82	18	,	,	PUNCT
fnp-3025	82	19	remains	remain	VERB
fnp-3025	82	20	a	a	DET
fnp-3025	82	21	critical	critical	ADJ
fnp-3025	82	22	unsolved	unsolved	ADJ
fnp-3025	82	23	problem	problem	NOUN
fnp-3025	82	24	[	[	X
fnp-3025	82	25	45	45	NUM
fnp-3025	82	26	,	,	PUNCT
fnp-3025	82	27	83	83	NUM
fnp-3025	82	28	,	,	PUNCT
fnp-3025	82	29	84	84	NUM
fnp-3025	82	30	]	]	PUNCT
fnp-3025	82	31	.	.	PUNCT
fnp-3025	83	1	2	2	X
fnp-3025	83	2	.	.	X
fnp-3025	83	3	the	the	DET
fnp-3025	83	4	discovery	discovery	NOUN
fnp-3025	83	5	and	and	CCONJ
fnp-3025	83	6	early	early	ADJ
fnp-3025	83	7	exploration	exploration	NOUN
fnp-3025	83	8	of	of	ADP
fnp-3025	83	9	plaques	plaque	NOUN
fnp-3025	83	10	the	the	DET
fnp-3025	83	11	late	late	ADJ
fnp-3025	83	12	19th	19th	NOUN
fnp-3025	83	13	and	and	CCONJ
fnp-3025	83	14	early	early	ADJ
fnp-3025	83	15	20th	20th	ADJ
fnp-3025	83	16	centuries	century	NOUN
fnp-3025	83	17	saw	see	VERB
fnp-3025	83	18	a	a	DET
fnp-3025	83	19	profusion	profusion	NOUN
fnp-3025	83	20	of	of	ADP
fnp-3025	83	21	new	new	ADJ
fnp-3025	83	22	staining	staining	ADJ
fnp-3025	83	23	methods	method	NOUN
fnp-3025	83	24	that	that	PRON
fnp-3025	83	25	selectively	selectively	ADV
fnp-3025	83	26	revealed	reveal	VERB
fnp-3025	83	27	various	various	ADJ
fnp-3025	83	28	elements	element	NOUN
fnp-3025	83	29	in	in	ADP
fnp-3025	83	30	cells	cell	NOUN
fnp-3025	83	31	and	and	CCONJ
fnp-3025	83	32	tissues	tissue	NOUN
fnp-3025	83	33	[	[	X
fnp-3025	83	34	85	85	NUM
fnp-3025	83	35	]	]	PUNCT
fnp-3025	83	36	.	.	PUNCT
fnp-3025	84	1	accordingly	accordingly	ADV
fnp-3025	84	2	,	,	PUNCT
fnp-3025	84	3	the	the	DET
fnp-3025	84	4	original	original	ADJ
fnp-3025	84	5	depictions	depiction	NOUN
fnp-3025	84	6	of	of	ADP
fnp-3025	84	7	plaques	plaque	NOUN
fnp-3025	84	8	reflected	reflect	VERB
fnp-3025	84	9	what	what	PRON
fnp-3025	84	10	was	be	AUX
fnp-3025	84	11	disclosed	disclose	VERB
fnp-3025	84	12	by	by	ADP
fnp-3025	84	13	histologic	histologic	ADJ
fnp-3025	84	14	stains	stain	NOUN
fnp-3025	84	15	and	and	CCONJ
fnp-3025	84	16	viewed	view	VERB
fnp-3025	84	17	with	with	ADP
fnp-3025	84	18	the	the	DET
fnp-3025	84	19	light	light	ADJ
fnp-3025	84	20	microscope	microscope	NOUN
fnp-3025	84	21	.	.	PUNCT
fnp-3025	85	1	in	in	ADP
fnp-3025	85	2	1892	1892	NUM
fnp-3025	85	3	,	,	PUNCT
fnp-3025	85	4	paul	paul	PROPN
fnp-3025	85	5	blocq	blocq	PROPN
fnp-3025	85	6	and	and	CCONJ
fnp-3025	85	7	georges	georges	PROPN
fnp-3025	85	8	marinesco	marinesco	PROPN
fnp-3025	85	9	at	at	ADP
fnp-3025	85	10	the	the	DET
fnp-3025	85	11	salpêtrière	salpêtrière	PROPN
fnp-3025	85	12	hospital	hospital	NOUN
fnp-3025	85	13	in	in	ADP
fnp-3025	85	14	paris	paris	PROPN
fnp-3025	85	15	reported	report	VERB
fnp-3025	85	16	microscopic	microscopic	ADJ
fnp-3025	85	17	‘	'	PUNCT
fnp-3025	85	18	amas	amas	ADJ
fnp-3025	85	19	ronds	rond	NOUN
fnp-3025	85	20	’	'	PUNCT
fnp-3025	85	21	(	(	PUNCT
fnp-3025	85	22	‘	'	PUNCT
fnp-3025	85	23	round	round	ADJ
fnp-3025	85	24	clusters	cluster	NOUN
fnp-3025	85	25	’	'	PUNCT
fnp-3025	85	26	,	,	PUNCT
fnp-3025	85	27	or	or	CCONJ
fnp-3025	85	28	‘	'	PUNCT
fnp-3025	85	29	round	round	ADJ
fnp-3025	85	30	heaps	heap	NOUN
fnp-3025	85	31	’	'	PUNCT
fnp-3025	85	32	)	)	PUNCT
fnp-3025	85	33	or	or	CCONJ
fnp-3025	85	34	‘	'	PUNCT
fnp-3025	85	35	nodules	nodule	NOUN
fnp-3025	85	36	de	de	ADP
fnp-3025	85	37	sclérose	sclérose	NOUN
fnp-3025	85	38	névroglique	névroglique	NOUN
fnp-3025	85	39	’	'	PUNCT
fnp-3025	85	40	(	(	PUNCT
fnp-3025	85	41	‘	'	PUNCT
fnp-3025	85	42	nodules	nodule	NOUN
fnp-3025	85	43	of	of	ADP
fnp-3025	85	44	neuroglial	neuroglial	ADJ
fnp-3025	85	45	sclerosis	sclerosis	NOUN
fnp-3025	85	46	’	'	PUNCT
fnp-3025	85	47	)	)	PUNCT
fnp-3025	85	48	in	in	ADP
fnp-3025	85	49	the	the	DET
fnp-3025	85	50	brains	brain	NOUN
fnp-3025	85	51	of	of	ADP
fnp-3025	85	52	older	old	ADJ
fnp-3025	85	53	epileptic	epileptic	ADJ
fnp-3025	85	54	patients	patient	NOUN
fnp-3025	85	55	[	[	X
fnp-3025	85	56	86].1	86].1	NUM
fnp-3025	85	57	this	this	DET
fnp-3025	85	58	report	report	NOUN
fnp-3025	85	59	is	be	AUX
fnp-3025	85	60	generally	generally	ADV
fnp-3025	85	61	considered	consider	VERB
fnp-3025	85	62	to	to	PART
fnp-3025	85	63	be	be	AUX
fnp-3025	85	64	the	the	DET
fnp-3025	85	65	first	first	ADJ
fnp-3025	85	66	unambiguous	unambiguous	ADJ
fnp-3025	85	67	identification	identification	NOUN
fnp-3025	85	68	of	of	ADP
fnp-3025	85	69	plaques	plaque	NOUN
fnp-3025	85	70	in	in	ADP
fnp-3025	85	71	the	the	DET
fnp-3025	85	72	senescent	senescent	ADJ
fnp-3025	85	73	brain	brain	NOUN
fnp-3025	86	1	[	[	X
fnp-3025	86	2	81	81	NUM
fnp-3025	86	3	,	,	PUNCT
fnp-3025	86	4	87	87	NUM
fnp-3025	86	5	]	]	PUNCT
fnp-3025	86	6	.	.	PUNCT
fnp-3025	87	1	in	in	ADP
fnp-3025	87	2	1898	1898	NUM
fnp-3025	87	3	,	,	PUNCT
fnp-3025	87	4	emil	emil	PROPN
fnp-3025	87	5	redlich	redlich	PROPN
fnp-3025	87	6	published	publish	VERB
fnp-3025	87	7	evidence	evidence	NOUN
fnp-3025	87	8	linking	link	VERB
fnp-3025	87	9	plaques	plaque	NOUN
fnp-3025	87	10	to	to	ADP
fnp-3025	87	11	dementia	dementia	NOUN
fnp-3025	87	12	[	[	X
fnp-3025	87	13	88	88	NUM
fnp-3025	87	14	]	]	PUNCT
fnp-3025	87	15	;	;	PUNCT
fnp-3025	87	16	in	in	ADP
fnp-3025	87	17	the	the	DET
fnp-3025	87	18	brains	brain	NOUN
fnp-3025	87	19	of	of	ADP
fnp-3025	87	20	three	three	NUM
fnp-3025	87	21	elderly	elderly	ADJ
fnp-3025	87	22	subjects	subject	NOUN
fnp-3025	87	23	,	,	PUNCT
fnp-3025	87	24	two	two	NUM
fnp-3025	87	25	of	of	ADP
fnp-3025	87	26	whom	whom	PRON
fnp-3025	87	27	had	have	AUX
fnp-3025	87	28	died	die	VERB
fnp-3025	87	29	with	with	ADP
fnp-3025	87	30	clinically	clinically	ADV
fnp-3025	87	31	confirmed	confirm	VERB
fnp-3025	87	32	dementia	dementia	NOUN
fnp-3025	87	33	,	,	PUNCT
fnp-3025	87	34	redlich	redlich	PROPN
fnp-3025	87	35	described	describe	VERB
fnp-3025	87	36	the	the	DET
fnp-3025	87	37	structures	structure	NOUN
fnp-3025	87	38	as	as	ADP
fnp-3025	87	39	consisting	consist	VERB
fnp-3025	87	40	of	of	ADP
fnp-3025	87	41	a	a	DET
fnp-3025	87	42	core	core	NOUN
fnp-3025	87	43	of	of	ADP
fnp-3025	87	44	uncertain	uncertain	ADJ
fnp-3025	87	45	substance	substance	NOUN
fnp-3025	87	46	along	along	ADP
fnp-3025	87	47	with	with	ADP
fnp-3025	87	48	surrounding	surround	VERB
fnp-3025	87	49	astrocytes	astrocyte	NOUN
fnp-3025	87	50	(	(	PUNCT
fnp-3025	87	51	‘	'	PUNCT
fnp-3025	87	52	spinnenzellen	spinnenzellen	ADJ
fnp-3025	87	53	’	'	PUNCT
fnp-3025	87	54	)	)	PUNCT
fnp-3025	87	55	and	and	CCONJ
fnp-3025	87	56	their	their	PRON
fnp-3025	87	57	processes	process	NOUN
fnp-3025	87	58	.	.	PUNCT
fnp-3025	88	1	because	because	SCONJ
fnp-3025	88	2	they	they	PRON
fnp-3025	88	3	resembled	resemble	VERB
fnp-3025	88	4	millet	millet	NOUN
fnp-3025	88	5	seeds	seed	NOUN
fnp-3025	88	6	under	under	ADP
fnp-3025	88	7	the	the	DET
fnp-3025	88	8	microscope	microscope	NOUN
fnp-3025	88	9	,	,	PUNCT
fnp-3025	88	10	he	he	PRON
fnp-3025	88	11	referred	refer	VERB
fnp-3025	88	12	to	to	ADP
fnp-3025	88	13	these	these	DET
fnp-3025	88	14	collective	collective	ADJ
fnp-3025	88	15	lesions	lesion	NOUN
fnp-3025	88	16	as	as	ADP
fnp-3025	88	17	‘	'	PUNCT
fnp-3025	88	18	miliary	miliary	ADJ
fnp-3025	88	19	sclerosis	sclerosis	NOUN
fnp-3025	88	20	’	'	PUNCT
fnp-3025	88	21	(	(	PUNCT
fnp-3025	88	22	‘	'	PUNCT
fnp-3025	88	23	miliare	miliare	NOUN
fnp-3025	88	24	sklerose	sklerose	ADJ
fnp-3025	88	25	’	'	PUNCT
fnp-3025	88	26	)	)	PUNCT
fnp-3025	88	27	.	.	PUNCT
fnp-3025	89	1	notably	notably	ADV
fnp-3025	89	2	,	,	PUNCT
fnp-3025	89	3	redlich	redlich	PROPN
fnp-3025	89	4	also	also	ADV
fnp-3025	89	5	dubbed	dub	VERB
fnp-3025	89	6	them	they	PRON
fnp-3025	89	7	‘	'	PUNCT
fnp-3025	89	8	plaques	plaque	NOUN
fnp-3025	89	9	’	'	PUNCT
fnp-3025	89	10	,	,	PUNCT
fnp-3025	89	11	a	a	DET
fnp-3025	89	12	term	term	NOUN
fnp-3025	89	13	that	that	PRON
fnp-3025	89	14	was	be	AUX
fnp-3025	89	15	expanded	expand	VERB
fnp-3025	89	16	to	to	ADP
fnp-3025	89	17	‘	'	PUNCT
fnp-3025	89	18	senile	senile	ADJ
fnp-3025	89	19	plaques	plaque	NOUN
fnp-3025	89	20	’	'	PUNCT
fnp-3025	89	21	by	by	ADP
fnp-3025	89	22	simchowicz	simchowicz	NOUN
fnp-3025	89	23	in	in	ADP
fnp-3025	89	24	1911	1911	NUM
fnp-3025	89	25	[	[	X
fnp-3025	89	26	89	89	NUM
fnp-3025	89	27	]	]	PUNCT
fnp-3025	89	28	.	.	PUNCT
fnp-3025	90	1	furthermore	furthermore	ADV
fnp-3025	90	2	,	,	PUNCT
fnp-3025	90	3	redlich	redlich	PROPN
fnp-3025	90	4	noted	note	VERB
fnp-3025	90	5	that	that	SCONJ
fnp-3025	90	6	some	some	DET
fnp-3025	90	7	smaller	small	ADJ
fnp-3025	90	8	lesions	lesion	NOUN
fnp-3025	90	9	consisted	consist	VERB
fnp-3025	90	10	of	of	ADP
fnp-3025	90	11	fine	fine	ADJ
fnp-3025	90	12	fibers	fiber	NOUN
fnp-3025	90	13	with	with	ADP
fnp-3025	90	14	a	a	DET
fnp-3025	90	15	cotton	cotton	NOUN
fnp-3025	90	16	-	-	PUNCT
fnp-3025	90	17	like	like	ADJ
fnp-3025	90	18	appearance	appearance	NOUN
fnp-3025	90	19	[	[	X
fnp-3025	90	20	88	88	NUM
fnp-3025	90	21	]	]	PUNCT
fnp-3025	90	22	,	,	PUNCT
fnp-3025	90	23	anticipating	anticipate	VERB
fnp-3025	90	24	the	the	DET
fnp-3025	90	25	use	use	NOUN
fnp-3025	90	26	of	of	ADP
fnp-3025	90	27	the	the	DET
fnp-3025	90	28	term	term	NOUN
fnp-3025	90	29	‘	'	PUNCT
fnp-3025	90	30	cotton	cotton	NOUN
fnp-3025	90	31	-	-	PUNCT
fnp-3025	90	32	wool	wool	NOUN
fnp-3025	90	33	plaques	plaque	NOUN
fnp-3025	90	34	’	'	PUNCT
fnp-3025	90	35	to	to	PART
fnp-3025	90	36	depict	depict	VERB
fnp-3025	90	37	certain	certain	ADJ
fnp-3025	90	38	types	type	NOUN
fnp-3025	90	39	of	of	ADP
fnp-3025	90	40	deposit	deposit	NOUN
fnp-3025	90	41	today	today	NOUN
fnp-3025	90	42	[	[	X
fnp-3025	90	43	90	90	NUM
fnp-3025	90	44	-	-	SYM
fnp-3025	90	45	94	94	NUM
fnp-3025	90	46	]	]	PUNCT
fnp-3025	90	47	.	.	PUNCT
fnp-3025	91	1	although	although	SCONJ
fnp-3025	91	2	alois	alois	PROPN
fnp-3025	91	3	alzheimer	alzheimer	PROPN
fnp-3025	91	4	is	be	AUX
fnp-3025	91	5	often	often	ADV
fnp-3025	91	6	credited	credit	VERB
fnp-3025	91	7	with	with	ADP
fnp-3025	91	8	instigating	instigate	VERB
fnp-3025	91	9	the	the	DET
fnp-3025	91	10	burst	burst	NOUN
fnp-3025	91	11	of	of	ADP
fnp-3025	91	12	scientific	scientific	ADJ
fnp-3025	91	13	analyses	analysis	NOUN
fnp-3025	91	14	of	of	ADP
fnp-3025	91	15	plaques	plaque	NOUN
fnp-3025	91	16	with	with	ADP
fnp-3025	91	17	his	his	PRON
fnp-3025	91	18	1906	1906	NUM
fnp-3025	91	19	conference	conference	NOUN
fnp-3025	91	20	presentation	presentation	NOUN
fnp-3025	91	21	in	in	ADP
fnp-3025	91	22	tübingen	tübingen	PROPN
fnp-3025	91	23	(	(	PUNCT
fnp-3025	91	24	published	publish	VERB
fnp-3025	91	25	in	in	ADP
fnp-3025	91	26	1907	1907	NUM
fnp-3025	91	27	)	)	PUNCT
fnp-3025	92	1	[	[	X
fnp-3025	92	2	95	95	NUM
fnp-3025	92	3	]	]	PUNCT
fnp-3025	92	4	,	,	PUNCT
fnp-3025	92	5	his	his	PRON
fnp-3025	92	6	report	report	NOUN
fnp-3025	92	7	was	be	AUX
fnp-3025	92	8	brief	brief	ADJ
fnp-3025	92	9	,	,	PUNCT
fnp-3025	92	10	and	and	CCONJ
fnp-3025	92	11	plaques	plaque	NOUN
fnp-3025	92	12	(	(	PUNCT
fnp-3025	92	13	‘	'	PUNCT
fnp-3025	92	14	miliary	miliary	ADJ
fnp-3025	92	15	foci	focus	NOUN
fnp-3025	92	16	’	'	PUNCT
fnp-3025	92	17	)	)	PUNCT
fnp-3025	92	18	were	be	AUX
fnp-3025	92	19	only	only	ADV
fnp-3025	92	20	superficially	superficially	ADV
fnp-3025	92	21	mentioned.2	mentioned.2	VERB
fnp-3025	92	22	he	he	PRON
fnp-3025	92	23	did	do	AUX
fnp-3025	92	24	not	not	PART
fnp-3025	92	25	issue	issue	VERB
fnp-3025	92	26	his	his	PRON
fnp-3025	92	27	first	first	ADJ
fnp-3025	92	28	detailed	detailed	ADJ
fnp-3025	92	29	histopathologic	histopathologic	NOUN
fnp-3025	92	30	examination	examination	NOUN
fnp-3025	92	31	of	of	ADP
fnp-3025	92	32	plaques	plaque	NOUN
fnp-3025	92	33	until	until	ADP
fnp-3025	92	34	1911	1911	NUM
fnp-3025	93	1	[	[	X
fnp-3025	93	2	96	96	NUM
fnp-3025	93	3	]	]	PUNCT
fnp-3025	93	4	.	.	PUNCT
fnp-3025	94	1	in	in	ADP
fnp-3025	94	2	fact	fact	NOUN
fnp-3025	94	3	,	,	PUNCT
fnp-3025	94	4	along	along	ADP
fnp-3025	94	5	with	with	ADP
fnp-3025	94	6	redlich	redlich	NOUN
fnp-3025	94	7	[	[	X
fnp-3025	94	8	88	88	NUM
fnp-3025	94	9	]	]	PUNCT
fnp-3025	94	10	,	,	PUNCT
fnp-3025	94	11	a	a	DET
fnp-3025	94	12	good	good	ADJ
fnp-3025	94	13	case	case	NOUN
fnp-3025	94	14	can	can	AUX
fnp-3025	94	15	be	be	AUX
fnp-3025	94	16	made	make	VERB
fnp-3025	94	17	that	that	SCONJ
fnp-3025	94	18	oskar	oskar	PROPN
fnp-3025	94	19	fischer	fischer	PROPN
fnp-3025	94	20	deserves	deserve	VERB
fnp-3025	94	21	the	the	DET
fnp-3025	94	22	credit	credit	NOUN
fnp-3025	94	23	for	for	ADP
fnp-3025	94	24	initiating	initiate	VERB
fnp-3025	94	25	the	the	DET
fnp-3025	94	26	modern	modern	ADJ
fnp-3025	94	27	histopathologic	histopathologic	ADJ
fnp-3025	94	28	analysis	analysis	NOUN
fnp-3025	94	29	of	of	ADP
fnp-3025	94	30	dementia	dementia	NOUN
fnp-3025	94	31	with	with	ADP
fnp-3025	94	32	a	a	DET
fnp-3025	94	33	comprehensive	comprehensive	ADJ
fnp-3025	94	34	series	series	NOUN
fnp-3025	94	35	of	of	ADP
fnp-3025	94	36	reports	report	NOUN
fnp-3025	94	37	published	publish	VERB
fnp-3025	94	38	in	in	ADP
fnp-3025	94	39	1907	1907	NUM
fnp-3025	94	40	,	,	PUNCT
fnp-3025	94	41	1910	1910	NUM
fnp-3025	94	42	,	,	PUNCT
fnp-3025	94	43	and	and	CCONJ
fnp-3025	94	44	1912	1912	NUM
fnp-3025	95	1	[	[	X
fnp-3025	95	2	87	87	NUM
fnp-3025	95	3	]	]	PUNCT
fnp-3025	95	4	.	.	PUNCT
fnp-3025	96	1	several	several	ADJ
fnp-3025	96	2	other	other	ADJ
fnp-3025	96	3	researchers	researcher	NOUN
fnp-3025	96	4	contributed	contribute	VERB
fnp-3025	96	5	to	to	ADP
fnp-3025	96	6	the	the	DET
fnp-3025	96	7	literature	literature	NOUN
fnp-3025	96	8	on	on	ADP
fnp-3025	96	9	plaques	plaque	NOUN
fnp-3025	96	10	during	during	ADP
fnp-3025	96	11	this	this	DET
fnp-3025	96	12	period	period	NOUN
fnp-3025	96	13	,	,	PUNCT
fnp-3025	96	14	including	include	VERB
fnp-3025	96	15	,	,	PUNCT
fnp-3025	96	16	among	among	ADP
fnp-3025	96	17	others	other	NOUN
fnp-3025	96	18	,	,	PUNCT
fnp-3025	96	19	miyake	miyake	PROPN
fnp-3025	96	20	[	[	X
fnp-3025	96	21	97	97	NUM
fnp-3025	96	22	]	]	PUNCT
fnp-3025	96	23	,	,	PUNCT
fnp-3025	96	24	lafora	lafora	PROPN
fnp-3025	97	1	[	[	X
fnp-3025	97	2	98	98	NUM
fnp-3025	97	3	]	]	PUNCT
fnp-3025	97	4	,	,	PUNCT
fnp-3025	97	5	bonfiglio	bonfiglio	PROPN
fnp-3025	98	1	[	[	X
fnp-3025	98	2	99	99	NUM
fnp-3025	98	3	]	]	PUNCT
fnp-3025	98	4	,	,	PUNCT
fnp-3025	98	5	hübner	hübner	NOUN
fnp-3025	98	6	[	[	X
fnp-3025	98	7	100	100	NUM
fnp-3025	98	8	]	]	PUNCT
fnp-3025	98	9	,	,	PUNCT
fnp-3025	98	10	perusini	perusini	PROPN
fnp-3025	98	11	[	[	X
fnp-3025	98	12	101	101	NUM
fnp-3025	98	13	]	]	PUNCT
fnp-3025	98	14	,	,	PUNCT
fnp-3025	98	15	fuller	full	ADJ
fnp-3025	98	16	[	[	X
fnp-3025	98	17	102	102	NUM
fnp-3025	98	18	]	]	PUNCT
fnp-3025	98	19	,	,	PUNCT
fnp-3025	98	20	bielschowsky	bielschowsky	NOUN
fnp-3025	98	21	[	[	X
fnp-3025	98	22	103	103	NUM
fnp-3025	98	23	]	]	PUNCT
fnp-3025	98	24	,	,	PUNCT
fnp-3025	98	25	barrett	barrett	PROPN
fnp-3025	99	1	[	[	X
fnp-3025	99	2	104	104	NUM
fnp-3025	99	3	]	]	PUNCT
fnp-3025	99	4	,	,	PUNCT
fnp-3025	99	5	simchowicz	simchowicz	ADJ
fnp-3025	99	6	[	[	X
fnp-3025	99	7	105	105	NUM
fnp-3025	99	8	]	]	PUNCT
fnp-3025	99	9	and	and	CCONJ
fnp-3025	99	10	marinesco	marinesco	NOUN
fnp-3025	99	11	and	and	CCONJ
fnp-3025	99	12	minea	minea	ADJ
fnp-3025	99	13	[	[	X
fnp-3025	99	14	106	106	NUM
fnp-3025	99	15	]	]	PUNCT
fnp-3025	99	16	(	(	PUNCT
fnp-3025	99	17	see	see	AUX
fnp-3025	99	18	also	also	ADV
fnp-3025	99	19	christen	christen	VERB
fnp-3025	99	20	[	[	X
fnp-3025	99	21	107	107	NUM
fnp-3025	99	22	]	]	PUNCT
fnp-3025	99	23	for	for	ADP
fnp-3025	99	24	a	a	DET
fnp-3025	99	25	brief	brief	ADJ
fnp-3025	99	26	historical	historical	ADJ
fnp-3025	99	27	perspective	perspective	NOUN
fnp-3025	99	28	on	on	ADP
fnp-3025	99	29	this	this	DET
fnp-3025	99	30	period	period	NOUN
fnp-3025	99	31	of	of	ADP
fnp-3025	99	32	research	research	NOUN
fnp-3025	99	33	into	into	ADP
fnp-3025	99	34	what	what	PRON
fnp-3025	99	35	we	we	PRON
fnp-3025	99	36	now	now	ADV
fnp-3025	99	37	call	call	VERB
fnp-3025	99	38	ad	ad	NOUN
fnp-3025	99	39	)	)	PUNCT
fnp-3025	99	40	.	.	PUNCT
fnp-3025	100	1	both	both	DET
fnp-3025	100	2	alzheimer	alzheimer	PROPN
fnp-3025	100	3	and	and	CCONJ
fnp-3025	100	4	fischer	fischer	PROPN
fnp-3025	100	5	excelled	excel	VERB
fnp-3025	100	6	in	in	ADP
fnp-3025	100	7	their	their	PRON
fnp-3025	100	8	analysis	analysis	NOUN
fnp-3025	100	9	of	of	ADP
fnp-3025	100	10	plaques	plaque	NOUN
fnp-3025	100	11	by	by	ADP
fnp-3025	100	12	implementing	implement	VERB
fnp-3025	100	13	a	a	DET
fnp-3025	100	14	silver	silver	NOUN
fnp-3025	100	15	-	-	PUNCT
fnp-3025	100	16	based	base	VERB
fnp-3025	100	17	staining	staining	ADJ
fnp-3025	100	18	method	method	NOUN
fnp-3025	100	19	introduced	introduce	VERB
fnp-3025	100	20	by	by	ADP
fnp-3025	100	21	max	max	PROPN
fnp-3025	100	22	bielschowsky	bielschowsky	PROPN
fnp-3025	100	23	[	[	X
fnp-3025	100	24	87	87	NUM
fnp-3025	100	25	]	]	PUNCT
fnp-3025	100	26	(	(	PUNCT
fnp-3025	100	27	see	see	VERB
fnp-3025	100	28	braak	braak	NOUN
fnp-3025	100	29	and	and	CCONJ
fnp-3025	100	30	braak	braak	VERB
fnp-3025	101	1	[	[	X
fnp-3025	101	2	108	108	NUM
fnp-3025	101	3	]	]	PUNCT
fnp-3025	101	4	for	for	ADP
fnp-3025	101	5	a	a	DET
fnp-3025	101	6	nice	nice	ADJ
fnp-3025	101	7	summary	summary	NOUN
fnp-3025	101	8	of	of	ADP
fnp-3025	101	9	the	the	DET
fnp-3025	101	10	early	early	ADJ
fnp-3025	101	11	development	development	NOUN
fnp-3025	101	12	of	of	ADP
fnp-3025	101	13	silver	silver	NOUN
fnp-3025	101	14	stains).3	stains).3	PROPN
fnp-3025	101	15	alzheimer	alzheimer	PROPN
fnp-3025	101	16	did	do	VERB
fnp-3025	101	17	,	,	PUNCT
fnp-3025	101	18	however	however	ADV
fnp-3025	101	19	,	,	PUNCT
fnp-3025	101	20	correctly	correctly	ADV
fnp-3025	101	21	anticipate	anticipate	VERB
fnp-3025	101	22	the	the	DET
fnp-3025	101	23	evolution	evolution	NOUN
fnp-3025	101	24	of	of	ADP
fnp-3025	101	25	neurology	neurology	NOUN
fnp-3025	101	26	in	in	ADP
fnp-3025	101	27	his	his	PRON
fnp-3025	101	28	1907	1907	NUM
fnp-3025	101	29	publication	publication	NOUN
fnp-3025	101	30	,	,	PUNCT
fnp-3025	101	31	in	in	ADP
fnp-3025	101	32	which	which	PRON
fnp-3025	101	33	he	he	PRON
fnp-3025	101	34	contended	contend	VERB
fnp-3025	101	35	that	that	SCONJ
fnp-3025	101	36	the	the	DET
fnp-3025	101	37	time	time	NOUN
fnp-3025	101	38	had	have	AUX
fnp-3025	101	39	come	come	VERB
fnp-3025	101	40	to	to	PART
fnp-3025	101	41	define	define	VERB
fnp-3025	101	42	neurologic	neurologic	ADJ
fnp-3025	101	43	diseases	disease	NOUN
fnp-3025	101	44	based	base	VERB
fnp-3025	101	45	on	on	ADP
fnp-3025	101	46	both	both	DET
fnp-3025	101	47	their	their	PRON
fnp-3025	101	48	clinical	clinical	ADJ
fnp-3025	101	49	and	and	CCONJ
fnp-3025	101	50	histologic	histologic	ADJ
fnp-3025	101	51	characteristics	characteristic	NOUN
fnp-3025	101	52	[	[	X
fnp-3025	101	53	95].4	95].4	NUM
fnp-3025	101	54	this	this	DET
fnp-3025	101	55	view	view	NOUN
fnp-3025	101	56	has	have	VERB
fnp-3025	101	57	a	a	DET
fnp-3025	101	58	contemporary	contemporary	ADJ
fnp-3025	101	59	parallel	parallel	NOUN
fnp-3025	101	60	in	in	ADP
fnp-3025	101	61	the	the	DET
fnp-3025	101	62	call	call	NOUN
fnp-3025	101	63	by	by	ADP
fnp-3025	101	64	an	an	DET
fnp-3025	101	65	international	international	ADJ
fnp-3025	101	66	group	group	NOUN
fnp-3025	101	67	of	of	ADP
fnp-3025	101	68	experts	expert	NOUN
fnp-3025	101	69	for	for	ADP
fnp-3025	101	70	a	a	DET
fnp-3025	101	71	biological	biological	ADJ
fnp-3025	101	72	,	,	PUNCT
fnp-3025	101	73	rather	rather	ADV
fnp-3025	101	74	than	than	ADP
fnp-3025	101	75	syndromic	syndromic	ADJ
fnp-3025	101	76	,	,	PUNCT
fnp-3025	101	77	definition	definition	NOUN
fnp-3025	101	78	of	of	ADP
fnp-3025	101	79	ad	ad	NOUN
fnp-3025	101	80	[	[	X
fnp-3025	101	81	109	109	NUM
fnp-3025	101	82	]	]	PUNCT
fnp-3025	101	83	.	.	PUNCT
fnp-3025	102	1	furthermore	furthermore	ADV
fnp-3025	102	2	,	,	PUNCT
fnp-3025	102	3	alzheimer	alzheimer	PROPN
fnp-3025	102	4	noted	note	VERB
fnp-3025	102	5	in	in	ADP
fnp-3025	102	6	1911	1911	NUM
fnp-3025	102	7	the	the	DET
fnp-3025	102	8	prevailing	prevail	VERB
fnp-3025	102	9	technical	technical	ADJ
fnp-3025	102	10	inability	inability	NOUN
fnp-3025	102	11	to	to	PART
fnp-3025	102	12	identify	identify	VERB
fnp-3025	102	13	the	the	DET
fnp-3025	102	14	substance	substance	NOUN
fnp-3025	102	15	in	in	ADP
fnp-3025	102	16	the	the	DET
fnp-3025	102	17	plaque	plaque	NOUN
fnp-3025	102	18	core	core	NOUN
fnp-3025	102	19	:	:	PUNCT
fnp-3025	102	20	‘	'	PUNCT
fnp-3025	102	21	...	...	PUNCT
fnp-3025	102	22	we	we	PRON
fnp-3025	102	23	have	have	VERB
fnp-3025	102	24	to	to	PART
fnp-3025	102	25	consider	consider	VERB
fnp-3025	102	26	the	the	DET
fnp-3025	102	27	core	core	NOUN
fnp-3025	102	28	of	of	ADP
fnp-3025	102	29	the	the	DET
fnp-3025	102	30	plaque	plaque	NOUN
fnp-3025	102	31	as	as	ADP
fnp-3025	102	32	an	an	DET
fnp-3025	102	33	unorganized	unorganized	ADJ
fnp-3025	102	34	mass	mass	NOUN
fnp-3025	102	35	which	which	PRON
fnp-3025	102	36	emerges	emerge	VERB
fnp-3025	102	37	differently	differently	ADV
fnp-3025	102	38	with	with	ADP
fnp-3025	102	39	different	different	ADJ
fnp-3025	102	40	staining	stain	VERB
fnp-3025	102	41	methods	method	NOUN
fnp-3025	102	42	...	...	PUNCT
fnp-3025	102	43	as	as	SCONJ
fnp-3025	102	44	perusini	perusini	PROPN
fnp-3025	102	45	and	and	CCONJ
fnp-3025	102	46	fischer	fischer	NOUN
fnp-3025	102	47	have	have	AUX
fnp-3025	102	48	already	already	ADV
fnp-3025	102	49	explained	explain	VERB
fnp-3025	102	50	,	,	PUNCT
fnp-3025	102	51	we	we	PRON
fnp-3025	102	52	are	be	AUX
fnp-3025	102	53	not	not	PART
fnp-3025	102	54	at	at	ADP
fnp-3025	102	55	present	present	ADJ
fnp-3025	102	56	able	able	ADJ
fnp-3025	102	57	to	to	PART
fnp-3025	102	58	identify	identify	VERB
fnp-3025	102	59	this	this	DET
fnp-3025	102	60	mass	mass	NOUN
fnp-3025	102	61	with	with	ADP
fnp-3025	102	62	any	any	PRON
fnp-3025	102	63	of	of	ADP
fnp-3025	102	64	the	the	DET
fnp-3025	102	65	substances	substance	NOUN
fnp-3025	102	66	known	know	VERB
fnp-3025	102	67	in	in	ADP
fnp-3025	102	68	pathological	pathological	ADJ
fnp-3025	102	69	anatomy	anatomy	NOUN
fnp-3025	102	70	’	'	PUNCT
fnp-3025	102	71	(	(	PUNCT
fnp-3025	102	72	translation	translation	NOUN
fnp-3025	102	73	from	from	ADP
fnp-3025	102	74	[	[	X
fnp-3025	102	75	110	110	NUM
fnp-3025	102	76	]	]	PUNCT
fnp-3025	102	77	)	)	PUNCT
fnp-3025	102	78	.	.	PUNCT
fnp-3025	103	1	in	in	ADP
fnp-3025	103	2	addition	addition	NOUN
fnp-3025	103	3	,	,	PUNCT
fnp-3025	103	4	alzheimer	alzheimer	PROPN
fnp-3025	103	5	highlighted	highlight	VERB
fnp-3025	103	6	the	the	DET
fnp-3025	103	7	prominence	prominence	NOUN
fnp-3025	103	8	of	of	ADP
fnp-3025	103	9	glial	glial	ADJ
fnp-3025	103	10	cells	cell	NOUN
fnp-3025	103	11	in	in	ADP
fnp-3025	103	12	the	the	DET
fnp-3025	103	13	composition	composition	NOUN
fnp-3025	103	14	of	of	ADP
fnp-3025	103	15	plaques	plaque	NOUN
fnp-3025	103	16	[	[	X
fnp-3025	103	17	96	96	NUM
fnp-3025	103	18	]	]	X
fnp-3025	103	19	,	,	PUNCT
fnp-3025	103	20	a	a	DET
fnp-3025	103	21	subject	subject	NOUN
fnp-3025	103	22	that	that	PRON
fnp-3025	103	23	has	have	AUX
fnp-3025	103	24	gained	gain	VERB
fnp-3025	103	25	momentum	momentum	NOUN
fnp-3025	103	26	in	in	ADP
fnp-3025	103	27	the	the	DET
fnp-3025	103	28	21st	21st	ADJ
fnp-3025	103	29	century	century	NOUN
fnp-3025	103	30	,	,	PUNCT
fnp-3025	103	31	owing	owe	VERB
fnp-3025	103	32	in	in	ADP
fnp-3025	103	33	part	part	NOUN
fnp-3025	103	34	to	to	ADP
fnp-3025	103	35	the	the	DET
fnp-3025	103	36	identification	identification	NOUN
fnp-3025	103	37	of	of	ADP
fnp-3025	103	38	compelling	compelling	ADJ
fnp-3025	103	39	,	,	PUNCT
fnp-3025	103	40	glia	glia	NOUN
fnp-3025	103	41	-	-	PUNCT
fnp-3025	103	42	related	relate	VERB
fnp-3025	103	43	genetic	genetic	ADJ
fnp-3025	103	44	risk	risk	NOUN
fnp-3025	103	45	factors	factor	NOUN
fnp-3025	103	46	for	for	ADP
fnp-3025	103	47	ad	ad	NOUN
fnp-3025	103	48	[	[	X
fnp-3025	103	49	111	111	NUM
fnp-3025	103	50	-	-	SYM
fnp-3025	103	51	115	115	NUM
fnp-3025	103	52	]	]	PUNCT
fnp-3025	103	53	(	(	PUNCT
fnp-3025	103	54	see	see	VERB
fnp-3025	103	55	section	section	NOUN
fnp-3025	103	56	6.2	6.2	NUM
fnp-3025	103	57	)	)	PUNCT
fnp-3025	103	58	.	.	PUNCT
fnp-3025	104	1	from	from	ADP
fnp-3025	104	2	the	the	DET
fnp-3025	104	3	early	early	ADJ
fnp-3025	104	4	20th	20th	ADJ
fnp-3025	104	5	century	century	NOUN
fnp-3025	104	6	on	on	ADV
fnp-3025	104	7	,	,	PUNCT
fnp-3025	104	8	researchers	researcher	NOUN
fnp-3025	104	9	widely	widely	ADV
fnp-3025	104	10	agreed	agree	VERB
fnp-3025	104	11	that	that	SCONJ
fnp-3025	104	12	the	the	DET
fnp-3025	104	13	main	main	ADJ
fnp-3025	104	14	structural	structural	ADJ
fnp-3025	104	15	elements	element	NOUN
fnp-3025	104	16	comprising	comprise	VERB
fnp-3025	104	17	plaques	plaque	NOUN
fnp-3025	104	18	are	be	AUX
fnp-3025	104	19	abnormal	abnormal	ADJ
fnp-3025	104	20	neuronal	neuronal	ADJ
fnp-3025	104	21	processes	process	NOUN
fnp-3025	104	22	,	,	PUNCT
fnp-3025	104	23	altered	alter	VERB
fnp-3025	104	24	glial	glial	ADJ
fnp-3025	104	25	cells	cell	NOUN
fnp-3025	104	26	,	,	PUNCT
fnp-3025	104	27	and	and	CCONJ
fnp-3025	104	28	a	a	DET
fnp-3025	104	29	central	central	ADJ
fnp-3025	104	30	,	,	PUNCT
fnp-3025	104	31	disordered	disordered	ADJ
fnp-3025	104	32	mass	mass	NOUN
fnp-3025	104	33	of	of	ADP
fnp-3025	104	34	unidentified	unidentified	ADJ
fnp-3025	104	35	material	material	NOUN
fnp-3025	104	36	.	.	PUNCT
fnp-3025	105	1	in	in	ADP
fnp-3025	105	2	a	a	DET
fnp-3025	105	3	1929	1929	NUM
fnp-3025	105	4	review	review	NOUN
fnp-3025	105	5	,	,	PUNCT
fnp-3025	105	6	macdonald	macdonald	PROPN
fnp-3025	105	7	critchley	critchley	PROPN
fnp-3025	105	8	[	[	X
fnp-3025	105	9	116	116	X
fnp-3025	105	10	]	]	PUNCT
fnp-3025	105	11	wrote	write	VERB
fnp-3025	105	12	that	that	SCONJ
fnp-3025	105	13	the	the	DET
fnp-3025	105	14	‘	'	PUNCT
fnp-3025	105	15	modern	modern	ADJ
fnp-3025	105	16	conception	conception	NOUN
fnp-3025	105	17	of	of	ADP
fnp-3025	105	18	the	the	DET
fnp-3025	105	19	plaque	plaque	NOUN
fnp-3025	105	20	is	be	AUX
fnp-3025	105	21	that	that	PRON
fnp-3025	105	22	of	of	ADP
fnp-3025	105	23	a	a	DET
fnp-3025	105	24	reactionary	reactionary	ADJ
fnp-3025	105	25	change	change	NOUN
fnp-3025	105	26	directed	direct	VERB
fnp-3025	105	27	against	against	ADP
fnp-3025	105	28	a	a	DET
fnp-3025	105	29	specific	specific	ADJ
fnp-3025	105	30	metabolic	metabolic	NOUN
fnp-3025	105	31	process	process	NOUN
fnp-3025	105	32	of	of	ADP
fnp-3025	105	33	a	a	DET
fnp-3025	105	34	toxic	toxic	ADJ
fnp-3025	105	35	nature	nature	NOUN
fnp-3025	105	36	’	'	PUNCT
fnp-3025	105	37	(	(	PUNCT
fnp-3025	105	38	a	a	DET
fnp-3025	105	39	description	description	NOUN
fnp-3025	105	40	that	that	PRON
fnp-3025	105	41	,	,	PUNCT
fnp-3025	105	42	if	if	SCONJ
fnp-3025	105	43	we	we	PRON
fnp-3025	105	44	consider	consider	VERB
fnp-3025	105	45	the	the	DET
fnp-3025	105	46	material	material	NOUN
fnp-3025	105	47	in	in	ADP
fnp-3025	105	48	the	the	DET
fnp-3025	105	49	core	core	NOUN
fnp-3025	105	50	to	to	PART
fnp-3025	105	51	be	be	AUX
fnp-3025	105	52	the	the	DET
fnp-3025	105	53	key	key	ADJ
fnp-3025	105	54	toxic	toxic	ADJ
fnp-3025	105	55	substance	substance	NOUN
fnp-3025	105	56	,	,	PUNCT
fnp-3025	105	57	resonates	resonate	VERB
fnp-3025	105	58	with	with	ADP
fnp-3025	105	59	leading	lead	VERB
fnp-3025	105	60	21st	21st	ADJ
fnp-3025	105	61	century	century	NOUN
fnp-3025	105	62	concepts	concept	NOUN
fnp-3025	105	63	)	)	PUNCT
fnp-3025	105	64	.	.	PUNCT
fnp-3025	106	1	many	many	ADJ
fnp-3025	106	2	pioneering	pioneering	ADJ
fnp-3025	106	3	scientists	scientist	NOUN
fnp-3025	106	4	attempted	attempt	VERB
fnp-3025	106	5	to	to	PART
fnp-3025	106	6	explain	explain	VERB
fnp-3025	106	7	the	the	DET
fnp-3025	106	8	origin	origin	NOUN
fnp-3025	106	9	and	and	CCONJ
fnp-3025	106	10	nature	nature	NOUN
fnp-3025	106	11	of	of	ADP
fnp-3025	106	12	plaques	plaque	NOUN
fnp-3025	106	13	based	base	VERB
fnp-3025	106	14	on	on	ADP
fnp-3025	106	15	their	their	PRON
fnp-3025	106	16	interpretations	interpretation	NOUN
fnp-3025	106	17	of	of	ADP
fnp-3025	106	18	static	static	ADJ
fnp-3025	106	19	images	image	NOUN
fnp-3025	106	20	in	in	ADP
fnp-3025	106	21	selectively	selectively	ADV
fnp-3025	106	22	stained	stain	VERB
fnp-3025	106	23	tissue	tissue	NOUN
fnp-3025	106	24	sections	section	NOUN
fnp-3025	106	25	.	.	PUNCT
fnp-3025	107	1	not	not	PART
fnp-3025	107	2	surprisingly	surprisingly	ADV
fnp-3025	107	3	,	,	PUNCT
fnp-3025	107	4	disagreement	disagreement	NOUN
fnp-3025	107	5	was	be	AUX
fnp-3025	107	6	common	common	ADJ
fnp-3025	107	7	(	(	PUNCT
fnp-3025	107	8	see	see	VERB
fnp-3025	107	9	,	,	PUNCT
fnp-3025	107	10	e.g.	e.g.	ADV
fnp-3025	107	11	,	,	PUNCT
fnp-3025	107	12	[	[	X
fnp-3025	107	13	99	99	NUM
fnp-3025	107	14	]	]	PUNCT
fnp-3025	107	15	,	,	PUNCT
fnp-3025	107	16	[	[	X
fnp-3025	107	17	101	101	NUM
fnp-3025	107	18	]	]	PUNCT
fnp-3025	107	19	,	,	PUNCT
fnp-3025	107	20	[	[	X
fnp-3025	107	21	102	102	NUM
fnp-3025	107	22	]	]	PUNCT
fnp-3025	107	23	,	,	PUNCT
fnp-3025	107	24	[	[	X
fnp-3025	107	25	117	117	NUM
fnp-3025	107	26	]	]	NUM
fnp-3025	107	27	)	)	PUNCT
fnp-3025	107	28	.	.	PUNCT
fnp-3025	108	1	ferraro	ferraro	PROPN
fnp-3025	108	2	(	(	PUNCT
fnp-3025	108	3	1931	1931	NUM
fnp-3025	108	4	)	)	PUNCT
fnp-3025	108	5	summarized	summarize	VERB
fnp-3025	108	6	this	this	DET
fnp-3025	108	7	lack	lack	NOUN
fnp-3025	108	8	of	of	ADP
fnp-3025	108	9	consensus	consensus	NOUN
fnp-3025	108	10	:	:	PUNCT
fnp-3025	108	11	‘	'	PUNCT
fnp-3025	108	12	...	...	PUNCT
fnp-3025	108	13	one	one	NUM
fnp-3025	108	14	group	group	NOUN
fnp-3025	108	15	of	of	ADP
fnp-3025	108	16	investigators	investigator	NOUN
fnp-3025	108	17	favors	favor	VERB
fnp-3025	108	18	the	the	DET
fnp-3025	108	19	theory	theory	NOUN
fnp-3025	108	20	that	that	SCONJ
fnp-3025	108	21	[	[	X
fnp-3025	108	22	the	the	DET
fnp-3025	108	23	plaque	plaque	NOUN
fnp-3025	108	24	]	]	PUNCT
fnp-3025	108	25	originates	originate	NOUN
fnp-3025	108	26	from	from	ADP
fnp-3025	108	27	nerve	nerve	NOUN
fnp-3025	108	28	cells	cell	NOUN
fnp-3025	108	29	,	,	PUNCT
fnp-3025	108	30	another	another	PRON
fnp-3025	108	31	that	that	SCONJ
fnp-3025	108	32	it	it	PRON
fnp-3025	108	33	originates	originate	VERB
fnp-3025	108	34	from	from	ADP
fnp-3025	108	35	neuroglial	neuroglial	ADJ
fnp-3025	108	36	elements	element	NOUN
fnp-3025	108	37	,	,	PUNCT
fnp-3025	108	38	another	another	PRON
fnp-3025	108	39	from	from	ADP
fnp-3025	108	40	axis	axis	ADJ
fnp-3025	108	41	cylinders	cylinder	NOUN
fnp-3025	108	42	,	,	PUNCT
fnp-3025	108	43	and	and	CCONJ
fnp-3025	108	44	still	still	ADV
fnp-3025	108	45	another	another	PRON
fnp-3025	108	46	,	,	PUNCT
fnp-3025	108	47	from	from	ADP
fnp-3025	108	48	the	the	DET
fnp-3025	108	49	intercellular	intercellular	ADJ
fnp-3025	108	50	ground	ground	NOUN
fnp-3025	108	51	substance	substance	NOUN
fnp-3025	108	52	’	'	PUNCT
fnp-3025	109	1	[	[	X
fnp-3025	109	2	118	118	NUM
fnp-3025	109	3	]	]	PUNCT
fnp-3025	109	4	.	.	PUNCT
fnp-3025	110	1	soniat	soniat	PROPN
fnp-3025	110	2	remarked	remark	VERB
fnp-3025	110	3	in	in	ADP
fnp-3025	110	4	1941	1941	NUM
fnp-3025	110	5	that	that	SCONJ
fnp-3025	110	6	‘	'	PUNCT
fnp-3025	110	7	no	no	DET
fnp-3025	110	8	less	less	ADJ
fnp-3025	110	9	than	than	ADP
fnp-3025	110	10	twenty	twenty	NUM
fnp-3025	110	11	different	different	ADJ
fnp-3025	110	12	concepts	concept	NOUN
fnp-3025	110	13	concerning	concern	VERB
fnp-3025	110	14	their	their	PRON
fnp-3025	110	15	origin	origin	NOUN
fnp-3025	110	16	have	have	AUX
fnp-3025	110	17	appeared	appear	VERB
fnp-3025	110	18	in	in	ADP
fnp-3025	110	19	the	the	DET
fnp-3025	110	20	literature	literature	NOUN
fnp-3025	110	21	’	'	PUNCT
fnp-3025	111	1	[	[	X
fnp-3025	111	2	119	119	NUM
fnp-3025	111	3	]	]	PUNCT
fnp-3025	111	4	.	.	PUNCT
fnp-3025	112	1	as	as	ADV
fnp-3025	112	2	late	late	ADV
fnp-3025	112	3	as	as	ADP
fnp-3025	112	4	1960	1960	NUM
fnp-3025	112	5	,	,	PUNCT
fnp-3025	112	6	liss	liss	PROPN
fnp-3025	112	7	wrote	write	VERB
fnp-3025	112	8	,	,	PUNCT
fnp-3025	112	9	citing	cite	VERB
fnp-3025	112	10	three	three	NUM
fnp-3025	112	11	influential	influential	ADJ
fnp-3025	112	12	textbooks	textbook	NOUN
fnp-3025	112	13	on	on	ADP
fnp-3025	112	14	pathology	pathology	NOUN
fnp-3025	112	15	,	,	PUNCT
fnp-3025	112	16	that	that	SCONJ
fnp-3025	112	17	the	the	DET
fnp-3025	112	18	‘	'	PUNCT
fnp-3025	112	19	morphogenesis	morphogenesis	NOUN
fnp-3025	112	20	of	of	ADP
fnp-3025	112	21	senile	senile	ADJ
fnp-3025	112	22	plaques	plaque	NOUN
fnp-3025	112	23	remains	remain	VERB
fnp-3025	112	24	still	still	ADV
fnp-3025	112	25	an	an	DET
fnp-3025	112	26	unsettled	unsettled	ADJ
fnp-3025	112	27	and	and	CCONJ
fnp-3025	112	28	controversial	controversial	ADJ
fnp-3025	112	29	matter	matter	NOUN
fnp-3025	112	30	’	'	PUNCT
fnp-3025	112	31	[	[	X
fnp-3025	112	32	120	120	NUM
fnp-3025	112	33	]	]	PUNCT
fnp-3025	112	34	.	.	PUNCT
fnp-3025	113	1	a	a	DET
fnp-3025	113	2	crucial	crucial	ADJ
fnp-3025	113	3	question	question	NOUN
fnp-3025	113	4	,	,	PUNCT
fnp-3025	113	5	and	and	CCONJ
fnp-3025	113	6	a	a	DET
fnp-3025	113	7	source	source	NOUN
fnp-3025	113	8	of	of	ADP
fnp-3025	113	9	much	much	ADJ
fnp-3025	113	10	of	of	ADP
fnp-3025	113	11	the	the	DET
fnp-3025	113	12	discord	discord	NOUN
fnp-3025	113	13	among	among	ADP
fnp-3025	113	14	researchers	researcher	NOUN
fnp-3025	113	15	,	,	PUNCT
fnp-3025	113	16	was	be	AUX
fnp-3025	113	17	the	the	DET
fnp-3025	113	18	nature	nature	NOUN
fnp-3025	113	19	of	of	ADP
fnp-3025	113	20	the	the	DET
fnp-3025	113	21	plaque	plaque	NOUN
fnp-3025	113	22	core	core	NOUN
fnp-3025	113	23	what	what	PRON
fnp-3025	113	24	does	do	AUX
fnp-3025	113	25	it	it	PRON
fnp-3025	113	26	consist	consist	VERB
fnp-3025	113	27	of	of	ADP
fnp-3025	113	28	,	,	PUNCT
fnp-3025	113	29	how	how	SCONJ
fnp-3025	113	30	does	do	AUX
fnp-3025	113	31	it	it	PRON
fnp-3025	113	32	arise	arise	VERB
fnp-3025	113	33	,	,	PUNCT
fnp-3025	113	34	what	what	DET
fnp-3025	113	35	impact	impact	NOUN
fnp-3025	113	36	does	do	AUX
fnp-3025	113	37	it	it	PRON
fnp-3025	113	38	have	have	VERB
fnp-3025	113	39	,	,	PUNCT
fnp-3025	113	40	and	and	CCONJ
fnp-3025	113	41	what	what	PRON
fnp-3025	113	42	governs	govern	VERB
fnp-3025	113	43	the	the	DET
fnp-3025	113	44	proliferation	proliferation	NOUN
fnp-3025	113	45	of	of	ADP
fnp-3025	113	46	plaques	plaque	NOUN
fnp-3025	113	47	in	in	ADP
fnp-3025	113	48	the	the	DET
fnp-3025	113	49	brain	brain	NOUN
fnp-3025	113	50	?	?	PUNCT
fnp-3025	114	1	the	the	DET
fnp-3025	114	2	answers	answer	NOUN
fnp-3025	114	3	to	to	ADP
fnp-3025	114	4	these	these	DET
fnp-3025	114	5	questions	question	NOUN
fnp-3025	114	6	would	would	AUX
fnp-3025	114	7	not	not	PART
fnp-3025	114	8	begin	begin	VERB
fnp-3025	114	9	to	to	PART
fnp-3025	114	10	emerge	emerge	VERB
fnp-3025	114	11	for	for	ADP
fnp-3025	114	12	another	another	DET
fnp-3025	114	13	half	half	ADJ
fnp-3025	114	14	century	century	NOUN
fnp-3025	114	15	.	.	PUNCT
fnp-3025	115	1	in	in	ADP
fnp-3025	115	2	fact	fact	NOUN
fnp-3025	115	3	,	,	PUNCT
fnp-3025	115	4	no	no	DET
fnp-3025	115	5	compelling	compelling	ADJ
fnp-3025	115	6	conceptual	conceptual	ADJ
fnp-3025	115	7	insights	insight	NOUN
fnp-3025	115	8	immediately	immediately	ADV
fnp-3025	115	9	followed	follow	VERB
fnp-3025	115	10	the	the	DET
fnp-3025	115	11	initial	initial	ADJ
fnp-3025	115	12	flurry	flurry	NOUN
fnp-3025	115	13	of	of	ADP
fnp-3025	115	14	histopathological	histopathological	ADJ
fnp-3025	115	15	investigations	investigation	NOUN
fnp-3025	115	16	of	of	ADP
fnp-3025	115	17	plaques	plaque	NOUN
fnp-3025	115	18	,	,	PUNCT
fnp-3025	115	19	which	which	PRON
fnp-3025	115	20	,	,	PUNCT
fnp-3025	115	21	ultimately	ultimately	ADV
fnp-3025	115	22	,	,	PUNCT
fnp-3025	115	23	were	be	AUX
fnp-3025	115	24	hampered	hamper	VERB
fnp-3025	115	25	by	by	ADP
fnp-3025	115	26	limitations	limitation	NOUN
fnp-3025	115	27	in	in	ADP
fnp-3025	115	28	the	the	DET
fnp-3025	115	29	available	available	ADJ
fnp-3025	115	30	methods	method	NOUN
fnp-3025	115	31	[	[	X
fnp-3025	115	32	119	119	NUM
fnp-3025	115	33	,	,	PUNCT
fnp-3025	115	34	121	121	NUM
fnp-3025	115	35	]	]	PUNCT
fnp-3025	115	36	.	.	PUNCT
fnp-3025	116	1	beginning	begin	VERB
fnp-3025	116	2	in	in	ADP
fnp-3025	116	3	the	the	DET
fnp-3025	116	4	1960s	1960	NOUN
fnp-3025	116	5	,	,	PUNCT
fnp-3025	116	6	theoretical	theoretical	ADJ
fnp-3025	116	7	and	and	CCONJ
fnp-3025	116	8	analytical	analytical	ADJ
fnp-3025	116	9	advances	advance	NOUN
fnp-3025	116	10	accelerated	accelerate	VERB
fnp-3025	116	11	;	;	PUNCT
fnp-3025	116	12	electron	electron	NOUN
fnp-3025	116	13	-	-	PUNCT
fnp-3025	116	14	microscopic	microscopic	NOUN
fnp-3025	116	15	studies	study	NOUN
fnp-3025	116	16	showed	show	VERB
fnp-3025	116	17	that	that	SCONJ
fnp-3025	116	18	the	the	DET
fnp-3025	116	19	mature	mature	ADJ
fnp-3025	116	20	plaque	plaque	NOUN
fnp-3025	116	21	core	core	NOUN
fnp-3025	116	22	consists	consist	NOUN
fnp-3025	116	23	of	of	ADP
fnp-3025	116	24	amyloid	amyloid	NOUN
fnp-3025	116	25	fibrils	fibril	NOUN
fnp-3025	116	26	structurally	structurally	ADV
fnp-3025	116	27	similar	similar	ADJ
fnp-3025	116	28	to	to	ADP
fnp-3025	116	29	those	those	PRON
fnp-3025	116	30	in	in	ADP
fnp-3025	116	31	corporeal	corporeal	ADJ
fnp-3025	116	32	amyloidoses	amyloidose	NOUN
fnp-3025	116	33	[	[	X
fnp-3025	116	34	122	122	NUM
fnp-3025	116	35	,	,	PUNCT
fnp-3025	116	36	123	123	NUM
fnp-3025	116	37	]	]	PUNCT
fnp-3025	116	38	,	,	PUNCT
fnp-3025	116	39	and	and	CCONJ
fnp-3025	116	40	quantitative	quantitative	ADJ
fnp-3025	116	41	analyses	analysis	NOUN
fnp-3025	116	42	confirmed	confirm	VERB
fnp-3025	116	43	that	that	SCONJ
fnp-3025	116	44	plaque	plaque	NOUN
fnp-3025	116	45	load	load	NOUN
fnp-3025	116	46	in	in	ADP
fnp-3025	116	47	the	the	DET
fnp-3025	116	48	brain	brain	NOUN
fnp-3025	116	49	is	be	AUX
fnp-3025	116	50	linked	link	VERB
fnp-3025	116	51	to	to	ADP
fnp-3025	116	52	dementia	dementia	NOUN
fnp-3025	116	53	[	[	X
fnp-3025	116	54	124	124	NUM
fnp-3025	116	55	]	]	X
fnp-3025	116	56	.	.	PUNCT
fnp-3025	117	1	most	most	ADV
fnp-3025	117	2	important	important	ADJ
fnp-3025	117	3	,	,	PUNCT
fnp-3025	117	4	however	however	ADV
fnp-3025	117	5	,	,	PUNCT
fnp-3025	117	6	was	be	AUX
fnp-3025	117	7	the	the	DET
fnp-3025	117	8	molecular	molecular	ADJ
fnp-3025	117	9	decipherment	decipherment	NOUN
fnp-3025	117	10	of	of	ADP
fnp-3025	117	11	aβ	aβ	PRON
fnp-3025	117	12	as	as	ADP
fnp-3025	117	13	the	the	DET
fnp-3025	117	14	primary	primary	ADJ
fnp-3025	117	15	protein	protein	NOUN
fnp-3025	117	16	in	in	ADP
fnp-3025	117	17	cerebral	cerebral	ADJ
fnp-3025	117	18	amyloid	amyloid	NOUN
fnp-3025	117	19	by	by	ADP
fnp-3025	117	20	glenner	glenner	NOUN
fnp-3025	117	21	and	and	CCONJ
fnp-3025	117	22	wong	wong	PROPN
fnp-3025	118	1	[	[	X
fnp-3025	118	2	2	2	NUM
fnp-3025	118	3	,	,	PUNCT
fnp-3025	118	4	3	3	NUM
fnp-3025	118	5	]	]	PUNCT
fnp-3025	118	6	and	and	CCONJ
fnp-3025	118	7	masters	master	NOUN
fnp-3025	118	8	and	and	CCONJ
fnp-3025	118	9	colleagues	colleague	NOUN
fnp-3025	119	1	[	[	X
fnp-3025	119	2	4	4	NUM
fnp-3025	119	3	]	]	PUNCT
fnp-3025	119	4	.	.	PUNCT
fnp-3025	120	1	the	the	DET
fnp-3025	120	2	genetic	genetic	ADJ
fnp-3025	120	3	insights	insight	NOUN
fnp-3025	120	4	and	and	CCONJ
fnp-3025	120	5	technical	technical	ADJ
fnp-3025	120	6	tools	tool	NOUN
fnp-3025	120	7	resulting	result	VERB
fnp-3025	120	8	from	from	ADP
fnp-3025	120	9	this	this	DET
fnp-3025	120	10	discovery	discovery	NOUN
fnp-3025	120	11	ultimately	ultimately	ADV
fnp-3025	120	12	established	establish	VERB
fnp-3025	120	13	aβ	aβ	NOUN
fnp-3025	120	14	as	as	ADP
fnp-3025	120	15	a	a	DET
fnp-3025	120	16	critical	critical	ADJ
fnp-3025	120	17	player	player	NOUN
fnp-3025	120	18	in	in	ADP
fnp-3025	120	19	the	the	DET
fnp-3025	120	20	pathogenesis	pathogenesis	NOUN
fnp-3025	120	21	of	of	ADP
fnp-3025	120	22	ad	ad	NOUN
fnp-3025	120	23	,	,	PUNCT
fnp-3025	120	24	and	and	CCONJ
fnp-3025	120	25	the	the	DET
fnp-3025	120	26	plaques	plaque	NOUN
fnp-3025	120	27	that	that	PRON
fnp-3025	120	28	occur	occur	VERB
fnp-3025	120	29	in	in	ADP
fnp-3025	120	30	normal	normal	ADJ
fnp-3025	120	31	aging	aging	NOUN
fnp-3025	120	32	and	and	CCONJ
fnp-3025	120	33	ad	ad	NOUN
fnp-3025	120	34	could	could	AUX
fnp-3025	120	35	,	,	PUNCT
fnp-3025	120	36	for	for	ADP
fnp-3025	120	37	the	the	DET
fnp-3025	120	38	first	first	ADJ
fnp-3025	120	39	time	time	NOUN
fnp-3025	120	40	,	,	PUNCT
fnp-3025	120	41	be	be	AUX
fnp-3025	120	42	unified	unify	VERB
fnp-3025	120	43	by	by	ADP
fnp-3025	120	44	a	a	DET
fnp-3025	120	45	single	single	ADJ
fnp-3025	120	46	,	,	PUNCT
fnp-3025	120	47	omnipresent	omnipresent	NOUN
fnp-3025	120	48	component	component	NOUN
fnp-3025	120	49	aberrant	aberrant	NOUN
fnp-3025	120	50	aβ	aβ	PROPN
fnp-3025	120	51	.	.	PROPN
fnp-3025	120	52	1	1	NUM
fnp-3025	120	53	‘	'	PUNCT
fnp-3025	120	54	il	il	X
fnp-3025	120	55	existe	existe	PROPN
fnp-3025	120	56	de	de	PROPN
fnp-3025	120	57	plus	plus	CCONJ
fnp-3025	120	58	,	,	PUNCT
fnp-3025	120	59	disséminés	disséminés	NOUN
fnp-3025	120	60	dans	dan	NOUN
fnp-3025	120	61	les	les	X
fnp-3025	120	62	diverses	diverses	X
fnp-3025	120	63	couches	couch	NOUN
fnp-3025	120	64	de	de	ADP
fnp-3025	120	65	l’écorce	l’écorce	PROPN
fnp-3025	120	66	,	,	PUNCT
fnp-3025	120	67	de	de	X
fnp-3025	120	68	petits	petits	X
fnp-3025	120	69	amas	amas	PROPN
fnp-3025	120	70	ronds	rond	NOUN
fnp-3025	120	71	d’un	d’un	NOUN
fnp-3025	120	72	diamètre	diamètre	NOUN
fnp-3025	120	73	de	de	PROPN
fnp-3025	120	74	60	60	NUM
fnp-3025	120	75	µ	µ	X
fnp-3025	120	76	environ	environ	X
fnp-3025	120	77	,	,	PUNCT
fnp-3025	120	78	se	se	X
fnp-3025	120	79	distinguant	distinguant	PROPN
fnp-3025	120	80	du	du	PROPN
fnp-3025	120	81	reste	reste	PROPN
fnp-3025	120	82	du	du	PROPN
fnp-3025	120	83	tissu	tissu	PROPN
fnp-3025	120	84	par	par	PROPN
fnp-3025	120	85	une	une	PROPN
fnp-3025	120	86	coloration	coloration	PROPN
fnp-3025	120	87	beaucoup	beaucoup	NOUN
fnp-3025	120	88	plus	plus	CCONJ
fnp-3025	120	89	intense	intense	ADJ
fnp-3025	120	90	,	,	PUNCT
fnp-3025	120	91	à	à	X
fnp-3025	120	92	contours	contours	NOUN
fnp-3025	120	93	réguliers	régulier	NOUN
fnp-3025	120	94	.	.	PUNCT
fnp-3025	121	1	ils	ils	PROPN
fnp-3025	121	2	apparaissent	apparaissent	PROPN
fnp-3025	121	3	ainsi	ainsi	PROPN
fnp-3025	121	4	,	,	PUNCT
fnp-3025	121	5	parsemant	parsemant	PROPN
fnp-3025	121	6	discrètement	discrètement	NOUN
fnp-3025	121	7	le	le	X
fnp-3025	121	8	fond	fond	PROPN
fnp-3025	121	9	des	des	PROPN
fnp-3025	121	10	préparations	préparation	NOUN
fnp-3025	121	11	,	,	PUNCT
fnp-3025	121	12	d’une	d’une	ADJ
fnp-3025	121	13	structure	structure	NOUN
fnp-3025	121	14	vaguement	vaguement	NOUN
fnp-3025	121	15	pointillée	pointillée	NOUN
fnp-3025	121	16	,	,	PUNCT
fnp-3025	121	17	ce	ce	PROPN
fnp-3025	121	18	pourquoi	pourquoi	PROPN
fnp-3025	121	19	il	il	PROPN
fnp-3025	121	20	est	est	X
fnp-3025	121	21	permis	permis	PROPN
fnp-3025	121	22	de	de	PROPN
fnp-3025	121	23	considérer	considérer	PROPN
fnp-3025	121	24	quelques	quelques	PROPN
fnp-3025	121	25	-	-	PUNCT
fnp-3025	121	26	uns	uns	PROPN
fnp-3025	121	27	d’entre	d’entre	PROPN
fnp-3025	121	28	eux	eux	PROPN
fnp-3025	121	29	,	,	PUNCT
fnp-3025	121	30	au	au	PROPN
fnp-3025	121	31	moins	moins	PROPN
fnp-3025	121	32	,	,	PUNCT
fnp-3025	121	33	comme	comme	PROPN
fnp-3025	121	34	de	de	PROPN
fnp-3025	121	35	véritables	véritables	PROPN
fnp-3025	121	36	nodules	nodule	NOUN
fnp-3025	121	37	de	de	ADP
fnp-3025	121	38	sclérose	sclérose	PROPN
fnp-3025	121	39	névroglique	névroglique	ADJ
fnp-3025	121	40	(	(	PUNCT
fnp-3025	121	41	?	?	PUNCT
fnp-3025	121	42	)	)	PUNCT
fnp-3025	121	43	.	.	PUNCT
fnp-3025	121	44	’	'	PUNCT
fnp-3025	122	1	(	(	PUNCT
fnp-3025	122	2	question	question	NOUN
fnp-3025	122	3	mark	mark	NOUN
fnp-3025	122	4	is	be	AUX
fnp-3025	122	5	in	in	ADP
fnp-3025	122	6	the	the	DET
fnp-3025	122	7	original	original	ADJ
fnp-3025	122	8	)	)	PUNCT
fnp-3025	122	9	2	2	NUM
fnp-3025	122	10	‘	'	PUNCT
fnp-3025	122	11	über	über	NOUN
fnp-3025	122	12	die	die	NOUN
fnp-3025	122	13	ganze	ganze	PROPN
fnp-3025	122	14	rinde	rinde	PROPN
fnp-3025	122	15	zerstreut	zerstreut	PROPN
fnp-3025	122	16	,	,	PUNCT
fnp-3025	122	17	besonders	besonder	NOUN
fnp-3025	122	18	zahlreich	zahlreich	PRON
fnp-3025	122	19	in	in	ADP
fnp-3025	122	20	den	den	PROPN
fnp-3025	122	21	oberen	oberen	PROPN
fnp-3025	122	22	schichten	schichten	VERB
fnp-3025	122	23	,	,	PUNCT
fnp-3025	122	24	findet	findet	NOUN
fnp-3025	122	25	man	man	PROPN
fnp-3025	122	26	miliare	miliare	PROPN
fnp-3025	122	27	herdchen	herdchen	PROPN
fnp-3025	122	28	,	,	PUNCT
fnp-3025	122	29	welche	welche	PROPN
fnp-3025	122	30	durch	durch	PROPN
fnp-3025	122	31	einlagerung	einlagerung	PROPN
fnp-3025	122	32	eines	eine	NOUN
fnp-3025	122	33	eigenartigen	eigenartigen	ADJ
fnp-3025	122	34	stoffes	stoffe	NOUN
fnp-3025	122	35	in	in	ADP
fnp-3025	122	36	die	die	VERB
fnp-3025	122	37	hirnrinde	hirnrinde	ADJ
fnp-3025	122	38	bedingt	bedingt	ADJ
fnp-3025	122	39	sind	sind	NOUN
fnp-3025	122	40	.	.	PUNCT
fnp-3025	123	1	er	er	INTJ
fnp-3025	123	2	lässt	lässt	ADJ
fnp-3025	123	3	sich	sich	PROPN
fnp-3025	123	4	schon	schon	PROPN
fnp-3025	123	5	ohne	ohne	PROPN
fnp-3025	123	6	färbung	färbung	PROPN
fnp-3025	123	7	erkennen	erkennen	PROPN
fnp-3025	123	8	,	,	PUNCT
fnp-3025	123	9	ist	ist	ADJ
fnp-3025	123	10	aber	aber	PROPN
fnp-3025	123	11	färbungen	färbungen	PROPN
fnp-3025	123	12	gegenüber	gegenüber	PROPN
fnp-3025	123	13	sehr	sehr	PROPN
fnp-3025	123	14	refractär	refractär	PROPN
fnp-3025	123	15	.	.	PUNCT
fnp-3025	123	16	’	'	PUNCT
fnp-3025	124	1	3	3	NUM
fnp-3025	124	2	many	many	ADJ
fnp-3025	124	3	different	different	ADJ
fnp-3025	124	4	silver	silver	NOUN
fnp-3025	124	5	stains	stain	NOUN
fnp-3025	124	6	have	have	AUX
fnp-3025	124	7	been	be	AUX
fnp-3025	124	8	developed	develop	VERB
fnp-3025	124	9	to	to	PART
fnp-3025	124	10	detect	detect	VERB
fnp-3025	124	11	ad	ad	NOUN
fnp-3025	124	12	pathology	pathology	NOUN
fnp-3025	124	13	.	.	PUNCT
fnp-3025	125	1	each	each	DET
fnp-3025	125	2	method	method	NOUN
fnp-3025	125	3	selectively	selectively	ADV
fnp-3025	125	4	reveals	reveal	VERB
fnp-3025	125	5	certain	certain	ADJ
fnp-3025	125	6	elements	element	NOUN
fnp-3025	125	7	in	in	ADP
fnp-3025	125	8	the	the	DET
fnp-3025	125	9	plaques	plaque	NOUN
fnp-3025	125	10	,	,	PUNCT
fnp-3025	125	11	and	and	CCONJ
fnp-3025	125	12	they	they	PRON
fnp-3025	125	13	are	be	AUX
fnp-3025	125	14	sometimes	sometimes	ADV
fnp-3025	125	15	considered	consider	VERB
fnp-3025	125	16	to	to	PART
fnp-3025	125	17	be	be	AUX
fnp-3025	125	18	less	less	ADV
fnp-3025	125	19	sensitive	sensitive	ADJ
fnp-3025	125	20	than	than	SCONJ
fnp-3025	125	21	is	be	AUX
fnp-3025	125	22	immunostaining	immunostaine	VERB
fnp-3025	125	23	with	with	ADP
fnp-3025	125	24	antibodies	antibody	NOUN
fnp-3025	125	25	to	to	ADP
fnp-3025	125	26	aβ	aβ	PROPN
fnp-3025	125	27	.	.	PUNCT
fnp-3025	126	1	some	some	DET
fnp-3025	126	2	silver	silver	ADJ
fnp-3025	126	3	stains	stain	NOUN
fnp-3025	126	4	,	,	PUNCT
fnp-3025	126	5	however	however	ADV
fnp-3025	126	6	,	,	PUNCT
fnp-3025	126	7	are	be	AUX
fnp-3025	126	8	exquisitely	exquisitely	ADV
fnp-3025	126	9	sensitive	sensitive	ADJ
fnp-3025	126	10	even	even	ADV
fnp-3025	126	11	to	to	AUX
fnp-3025	126	12	small	small	ADJ
fnp-3025	126	13	,	,	PUNCT
fnp-3025	126	14	diffuse	diffuse	VERB
fnp-3025	126	15	aβ	aβ	ADP
fnp-3025	126	16	deposits	deposit	NOUN
fnp-3025	126	17	,	,	PUNCT
fnp-3025	126	18	which	which	PRON
fnp-3025	126	19	have	have	AUX
fnp-3025	126	20	been	be	AUX
fnp-3025	126	21	recognized	recognize	VERB
fnp-3025	126	22	in	in	ADP
fnp-3025	126	23	ad	ad	NOUN
fnp-3025	126	24	tissue	tissue	NOUN
fnp-3025	126	25	since	since	SCONJ
fnp-3025	126	26	the	the	DET
fnp-3025	126	27	early	early	ADJ
fnp-3025	126	28	20th	20th	ADJ
fnp-3025	126	29	century	century	NOUN
fnp-3025	126	30	(	(	PUNCT
fnp-3025	126	31	see	see	VERB
fnp-3025	126	32	,	,	PUNCT
fnp-3025	126	33	e.g.	e.g.	ADV
fnp-3025	126	34	,	,	PUNCT
fnp-3025	126	35	marinesco	marinesco	ADJ
fnp-3025	126	36	and	and	CCONJ
fnp-3025	126	37	minea	minea	ADJ
fnp-3025	126	38	[	[	X
fnp-3025	126	39	1912	1912	NUM
fnp-3025	126	40	]	]	PUNCT
fnp-3025	127	1	[	[	X
fnp-3025	127	2	reference	reference	NOUN
fnp-3025	127	3	106	106	NUM
fnp-3025	127	4	]	]	PUNCT
fnp-3025	127	5	and	and	CCONJ
fnp-3025	127	6	cowe	cowe	NOUN
fnp-3025	127	7	,	,	PUNCT
fnp-3025	127	8	a.	a.	NOUN
fnp-3025	128	1	[	[	X
fnp-3025	128	2	1915	1915	NUM
fnp-3025	128	3	]	]	PUNCT
fnp-3025	129	1	[	[	X
fnp-3025	129	2	reference	reference	NOUN
fnp-3025	129	3	508	508	NUM
fnp-3025	129	4	]	]	PUNCT
fnp-3025	129	5	)	)	PUNCT
fnp-3025	129	6	.	.	PUNCT
fnp-3025	130	1	note	note	NOUN
fnp-3025	130	2	also	also	ADV
fnp-3025	130	3	figure	figure	VERB
fnp-3025	130	4	23	23	NUM
fnp-3025	130	5	.	.	NOUN
fnp-3025	131	1	4	4	NUM
fnp-3025	131	2	‘	'	PUNCT
fnp-3025	131	3	es	es	X
fnp-3025	131	4	gibt	gibt	PROPN
fnp-3025	131	5	ganz	ganz	PROPN
fnp-3025	131	6	zweifellos	zweifellos	PROPN
fnp-3025	131	7	viel	viel	PROPN
fnp-3025	131	8	mehr	mehr	NOUN
fnp-3025	131	9	psychische	psychische	NOUN
fnp-3025	131	10	krankheiten	krankheiten	VERB
fnp-3025	131	11	,	,	PUNCT
fnp-3025	131	12	als	als	VERB
fnp-3025	131	13	sie	sie	PROPN
fnp-3025	131	14	unsere	unsere	PROPN
fnp-3025	131	15	lehrbücher	lehrbücher	PROPN
fnp-3025	131	16	aufführen	aufführen	PROPN
fnp-3025	131	17	.	.	PUNCT
fnp-3025	132	1	in	in	ADP
fnp-3025	132	2	manchen	manchen	PROPN
fnp-3025	132	3	solchen	solchen	PROPN
fnp-3025	132	4	fällen	fällen	ADJ
fnp-3025	132	5	wird	wird	NOUN
fnp-3025	132	6	dann	dann	PROPN
fnp-3025	132	7	eine	eine	PROPN
fnp-3025	132	8	spätere	spätere	ADP
fnp-3025	132	9	histologische	histologische	PROPN
fnp-3025	132	10	untersuchung	untersuchung	PROPN
fnp-3025	132	11	die	die	VERB
fnp-3025	132	12	besonderheit	besonderheit	PROPN
fnp-3025	132	13	des	des	PROPN
fnp-3025	132	14	falles	falles	PROPN
fnp-3025	132	15	feststellen	feststellen	PROPN
fnp-3025	132	16	lassen	lassen	PROPN
fnp-3025	132	17	.	.	PUNCT
fnp-3025	133	1	dann	dann	PROPN
fnp-3025	133	2	werden	werden	PROPN
fnp-3025	133	3	wir	wir	PROPN
fnp-3025	133	4	aber	aber	PROPN
fnp-3025	133	5	auch	auch	PROPN
fnp-3025	133	6	allmählich	allmählich	ADP
fnp-3025	133	7	dazu	dazu	PROPN
fnp-3025	133	8	kommen	kommen	PROPN
fnp-3025	133	9	,	,	PUNCT
fnp-3025	133	10	von	von	PROPN
fnp-3025	133	11	den	den	PROPN
fnp-3025	133	12	großen	großen	PROPN
fnp-3025	133	13	krankheitsgruppen	krankheitsgruppen	PROPN
fnp-3025	133	14	unserer	unserer	PROPN
fnp-3025	133	15	lehrbücher	lehrbücher	PROPN
fnp-3025	133	16	einzelne	einzelne	PROPN
fnp-3025	133	17	krankeiten	krankeiten	PROPN
fnp-3025	133	18	(	(	PUNCT
fnp-3025	133	19	sic	sic	ADJ
fnp-3025	133	20	)	)	PUNCT
fnp-3025	133	21	klinisch	klinisch	PROPN
fnp-3025	133	22	abzuscheiden	abzuscheiden	VERB
fnp-3025	133	23	und	und	PROPN
fnp-3025	133	24	jene	jene	PROPN
fnp-3025	133	25	selbst	selbst	PROPN
fnp-3025	133	26	klinisch	klinisch	VERB
fnp-3025	133	27	schärfer	schärfer	DET
fnp-3025	133	28	zu	zu	ADV
fnp-3025	133	29	umgrenzen	umgrenzen	ADJ
fnp-3025	133	30	.	.	PUNCT
fnp-3025	133	31	’	'	PUNCT
fnp-3025	134	1	3	3	X
fnp-3025	134	2	.	.	PUNCT
fnp-3025	134	3	plaque	plaque	ADJ
fnp-3025	134	4	nomenclature	nomenclature	NOUN
fnp-3025	134	5	:	:	PUNCT
fnp-3025	134	6	the	the	DET
fnp-3025	134	7	case	case	NOUN
fnp-3025	134	8	for	for	ADP
fnp-3025	134	9	‘	'	PUNCT
fnp-3025	134	10	aβ	aβ	DET
fnp-3025	134	11	plaques	plaque	NOUN
fnp-3025	134	12	’	'	PUNCT
fnp-3025	134	13	the	the	DET
fnp-3025	134	14	term	term	NOUN
fnp-3025	134	15	‘	'	PUNCT
fnp-3025	134	16	plaque	plaque	NOUN
fnp-3025	134	17	’	'	PUNCT
fnp-3025	134	18	(	(	PUNCT
fnp-3025	134	19	which	which	PRON
fnp-3025	134	20	historically	historically	ADV
fnp-3025	134	21	has	have	AUX
fnp-3025	134	22	referred	refer	VERB
fnp-3025	134	23	to	to	ADP
fnp-3025	134	24	a	a	DET
fnp-3025	134	25	flat	flat	ADJ
fnp-3025	134	26	object	object	NOUN
fnp-3025	134	27	such	such	ADJ
fnp-3025	134	28	as	as	ADP
fnp-3025	134	29	a	a	DET
fnp-3025	134	30	disk	disk	NOUN
fnp-3025	134	31	or	or	CCONJ
fnp-3025	134	32	tablet	tablet	NOUN
fnp-3025	134	33	)	)	PUNCT
fnp-3025	134	34	was	be	AUX
fnp-3025	134	35	adopted	adopt	VERB
fnp-3025	134	36	by	by	ADP
fnp-3025	134	37	the	the	DET
fnp-3025	134	38	medical	medical	ADJ
fnp-3025	134	39	community	community	NOUN
fnp-3025	134	40	in	in	ADP
fnp-3025	134	41	the	the	DET
fnp-3025	134	42	mid	mid	PROPN
fnp-3025	134	43	-	-	PUNCT
fnp-3025	134	44	to	to	ADP
fnp-3025	134	45	-	-	PUNCT
fnp-3025	134	46	late	late	ADV
fnp-3025	134	47	late	late	ADJ
fnp-3025	134	48	1800s	1800	NOUN
fnp-3025	134	49	to	to	PART
fnp-3025	134	50	designate	designate	VERB
fnp-3025	134	51	patch	patch	ADJ
fnp-3025	134	52	-	-	PUNCT
fnp-3025	134	53	like	like	ADJ
fnp-3025	134	54	abnormalities	abnormality	NOUN
fnp-3025	134	55	such	such	ADJ
fnp-3025	134	56	as	as	ADP
fnp-3025	134	57	atherosclerotic	atherosclerotic	ADJ
fnp-3025	134	58	plaque	plaque	NOUN
fnp-3025	134	59	or	or	CCONJ
fnp-3025	134	60	dental	dental	ADJ
fnp-3025	134	61	plaque.5	plaque.5	VERB
fnp-3025	134	62	redlich	redlich	NOUN
fnp-3025	134	63	[	[	X
fnp-3025	134	64	88	88	NUM
fnp-3025	134	65	]	]	PUNCT
fnp-3025	134	66	used	use	VERB
fnp-3025	134	67	the	the	DET
fnp-3025	134	68	term	term	NOUN
fnp-3025	134	69	to	to	PART
fnp-3025	134	70	describe	describe	VERB
fnp-3025	134	71	carmine	carmine	NOUN
fnp-3025	134	72	-	-	PUNCT
fnp-3025	134	73	stained	stain	VERB
fnp-3025	134	74	densities	density	NOUN
fnp-3025	134	75	(	(	PUNCT
fnp-3025	134	76	‘	'	PUNCT
fnp-3025	134	77	intensiv	intensiv	NOUN
fnp-3025	134	78	gefärbten	gefärbten	VERB
fnp-3025	134	79	plaques	plaque	NOUN
fnp-3025	134	80	’	'	PUNCT
fnp-3025	134	81	)	)	PUNCT
fnp-3025	134	82	,	,	PUNCT
fnp-3025	134	83	and	and	CCONJ
fnp-3025	134	84	simchowicz	simchowicz	NOUN
fnp-3025	135	1	[	[	X
fnp-3025	135	2	105	105	NUM
fnp-3025	135	3	]	]	PUNCT
fnp-3025	135	4	added	add	VERB
fnp-3025	135	5	the	the	DET
fnp-3025	135	6	modifier	modifier	NOUN
fnp-3025	135	7	‘	'	PUNCT
fnp-3025	135	8	senile	senile	NOUN
fnp-3025	135	9	’	'	PUNCT
fnp-3025	135	10	to	to	PART
fnp-3025	135	11	denote	denote	VERB
fnp-3025	135	12	their	their	PRON
fnp-3025	135	13	frequency	frequency	NOUN
fnp-3025	135	14	in	in	ADP
fnp-3025	135	15	senescent	senescent	ADJ
fnp-3025	135	16	brains	brain	NOUN
fnp-3025	135	17	,	,	PUNCT
fnp-3025	135	18	particularly	particularly	ADV
fnp-3025	135	19	in	in	ADP
fnp-3025	135	20	patients	patient	NOUN
fnp-3025	135	21	with	with	ADP
fnp-3025	135	22	senile	senile	ADJ
fnp-3025	135	23	dementia	dementia	NOUN
fnp-3025	135	24	[	[	X
fnp-3025	135	25	89	89	NUM
fnp-3025	135	26	]	]	PUNCT
fnp-3025	135	27	.	.	PUNCT
fnp-3025	136	1	most	most	ADJ
fnp-3025	136	2	plaques	plaque	NOUN
fnp-3025	136	3	in	in	ADP
fnp-3025	136	4	the	the	DET
fnp-3025	136	5	brain	brain	NOUN
fnp-3025	136	6	(	(	PUNCT
fnp-3025	136	7	unlike	unlike	ADP
fnp-3025	136	8	dental	dental	ADJ
fnp-3025	136	9	or	or	CCONJ
fnp-3025	136	10	atherosclerotic	atherosclerotic	ADJ
fnp-3025	136	11	plaque	plaque	NOUN
fnp-3025	136	12	)	)	PUNCT
fnp-3025	136	13	are	be	AUX
fnp-3025	136	14	not	not	PART
fnp-3025	136	15	planar	planar	ADJ
fnp-3025	136	16	(	(	PUNCT
fnp-3025	136	17	one	one	NUM
fnp-3025	136	18	exception	exception	NOUN
fnp-3025	136	19	being	be	AUX
fnp-3025	136	20	the	the	DET
fnp-3025	136	21	band	band	NOUN
fnp-3025	136	22	-	-	PUNCT
fnp-3025	136	23	like	like	ADJ
fnp-3025	136	24	subpial	subpial	ADJ
fnp-3025	136	25	deposits	deposit	NOUN
fnp-3025	136	26	[	[	X
fnp-3025	136	27	see	see	VERB
fnp-3025	136	28	figure	figure	NOUN
fnp-3025	136	29	9	9	NUM
fnp-3025	136	30	]	]	PUNCT
fnp-3025	136	31	)	)	PUNCT
fnp-3025	136	32	.	.	PUNCT
fnp-3025	137	1	of	of	ADP
fnp-3025	137	2	course	course	NOUN
fnp-3025	137	3	,	,	PUNCT
fnp-3025	137	4	spheroidal	spheroidal	NOUN
fnp-3025	137	5	plaques	plaque	NOUN
fnp-3025	137	6	appear	appear	VERB
fnp-3025	137	7	discoid	discoid	ADJ
fnp-3025	137	8	in	in	ADP
fnp-3025	137	9	histologic	histologic	ADJ
fnp-3025	137	10	sections	section	NOUN
fnp-3025	137	11	,	,	PUNCT
fnp-3025	137	12	and	and	CCONJ
fnp-3025	137	13	their	their	PRON
fnp-3025	137	14	apparent	apparent	ADJ
fnp-3025	137	15	size	size	NOUN
fnp-3025	137	16	and	and	CCONJ
fnp-3025	137	17	composition	composition	NOUN
fnp-3025	137	18	are	be	AUX
fnp-3025	137	19	influenced	influence	VERB
fnp-3025	137	20	by	by	ADP
fnp-3025	137	21	the	the	DET
fnp-3025	137	22	plane	plane	NOUN
fnp-3025	137	23	through	through	ADP
fnp-3025	137	24	which	which	PRON
fnp-3025	137	25	they	they	PRON
fnp-3025	137	26	are	be	AUX
fnp-3025	137	27	cut	cut	VERB
fnp-3025	137	28	(	(	PUNCT
fnp-3025	137	29	figure	figure	NOUN
fnp-3025	137	30	4	4	NUM
fnp-3025	137	31	)	)	PUNCT
fnp-3025	137	32	.	.	PUNCT
fnp-3025	138	1	figure	figure	VERB
fnp-3025	138	2	4	4	NUM
fnp-3025	138	3	.	.	PUNCT
fnp-3025	139	1	a	a	DET
fnp-3025	139	2	neuritic	neuritic	ADJ
fnp-3025	139	3	aβ	aβ	NOUN
fnp-3025	139	4	plaque	plaque	NOUN
fnp-3025	139	5	in	in	ADP
fnp-3025	139	6	consecutive	consecutive	ADJ
fnp-3025	139	7	sections	section	NOUN
fnp-3025	139	8	of	of	ADP
fnp-3025	139	9	the	the	DET
fnp-3025	139	10	cortex	cortex	NOUN
fnp-3025	139	11	from	from	ADP
fnp-3025	139	12	an	an	DET
fnp-3025	139	13	ad	ad	NOUN
fnp-3025	139	14	patient	patient	NOUN
fnp-3025	139	15	;	;	PUNCT
fnp-3025	139	16	the	the	DET
fnp-3025	139	17	core	core	NOUN
fnp-3025	139	18	is	be	AUX
fnp-3025	139	19	evident	evident	ADJ
fnp-3025	139	20	in	in	ADP
fnp-3025	139	21	the	the	DET
fnp-3025	139	22	left	left	ADJ
fnp-3025	139	23	-	-	PUNCT
fnp-3025	139	24	hand	hand	NOUN
fnp-3025	139	25	image	image	NOUN
fnp-3025	139	26	,	,	PUNCT
fnp-3025	139	27	whereas	whereas	SCONJ
fnp-3025	139	28	sections	section	NOUN
fnp-3025	139	29	through	through	ADP
fnp-3025	139	30	the	the	DET
fnp-3025	139	31	periphery	periphery	NOUN
fnp-3025	139	32	(	(	PUNCT
fnp-3025	139	33	middle	middle	ADJ
fnp-3025	139	34	and	and	CCONJ
fnp-3025	139	35	right	right	ADJ
fnp-3025	139	36	)	)	PUNCT
fnp-3025	139	37	reveal	reveal	VERB
fnp-3025	139	38	only	only	ADV
fnp-3025	139	39	neurites	neurite	NOUN
fnp-3025	139	40	(	(	PUNCT
fnp-3025	139	41	black	black	NOUN
fnp-3025	139	42	)	)	PUNCT
fnp-3025	139	43	.	.	PUNCT
fnp-3025	140	1	serial	serial	ADJ
fnp-3025	140	2	sections	section	NOUN
fnp-3025	140	3	may	may	AUX
fnp-3025	140	4	be	be	AUX
fnp-3025	140	5	required	require	VERB
fnp-3025	140	6	to	to	PART
fnp-3025	140	7	unequivocally	unequivocally	ADV
fnp-3025	140	8	identify	identify	VERB
fnp-3025	140	9	plaque	plaque	NOUN
fnp-3025	140	10	types	type	NOUN
fnp-3025	140	11	(	(	PUNCT
fnp-3025	140	12	a	a	DET
fnp-3025	140	13	technical	technical	ADJ
fnp-3025	140	14	caveat	caveat	NOUN
fnp-3025	140	15	noted	note	VERB
fnp-3025	140	16	by	by	ADP
fnp-3025	140	17	,	,	PUNCT
fnp-3025	140	18	among	among	ADP
fnp-3025	140	19	others	other	NOUN
fnp-3025	140	20	,	,	PUNCT
fnp-3025	140	21	alzheimer	alzheimer	PROPN
fnp-3025	141	1	[	[	X
fnp-3025	141	2	1911	1911	NUM
fnp-3025	141	3	]	]	PUNCT
fnp-3025	142	1	[	[	X
fnp-3025	142	2	reference	reference	NOUN
fnp-3025	142	3	96	96	NUM
fnp-3025	142	4	]	]	PUNCT
fnp-3025	142	5	)	)	PUNCT
fnp-3025	142	6	.	.	PUNCT
fnp-3025	143	1	naoumenko	naoumenko	NOUN
fnp-3025	143	2	-	-	PUNCT
fnp-3025	143	3	feigin	feigin	NOUN
fnp-3025	143	4	(	(	PUNCT
fnp-3025	143	5	silver	silver	NOUN
fnp-3025	143	6	)	)	PUNCT
fnp-3025	143	7	and	and	CCONJ
fnp-3025	143	8	periodic	periodic	ADJ
fnp-3025	143	9	-	-	PUNCT
fnp-3025	143	10	schiff	schiff	NOUN
fnp-3025	143	11	stains	stain	NOUN
fnp-3025	143	12	.	.	PUNCT
fnp-3025	144	1	bar	bar	NOUN
fnp-3025	144	2	=	=	PUNCT
fnp-3025	144	3	20	20	NUM
fnp-3025	144	4	μm	μm	NOUN
fnp-3025	144	5	for	for	ADP
fnp-3025	144	6	all	all	DET
fnp-3025	144	7	images	image	NOUN
fnp-3025	144	8	.	.	PUNCT
fnp-3025	145	1	some	some	PRON
fnp-3025	145	2	of	of	ADP
fnp-3025	145	3	the	the	DET
fnp-3025	145	4	designations	designation	NOUN
fnp-3025	145	5	for	for	ADP
fnp-3025	145	6	plaques	plaque	NOUN
fnp-3025	145	7	derive	derive	ADJ
fnp-3025	145	8	from	from	ADP
fnp-3025	145	9	their	their	PRON
fnp-3025	145	10	staining	stain	VERB
fnp-3025	145	11	characteristics	characteristic	NOUN
fnp-3025	145	12	.	.	PUNCT
fnp-3025	146	1	following	follow	VERB
fnp-3025	146	2	divry	divry	PROPN
fnp-3025	146	3	’s	’s	PART
fnp-3025	146	4	discovery	discovery	NOUN
fnp-3025	146	5	that	that	SCONJ
fnp-3025	146	6	certain	certain	ADJ
fnp-3025	146	7	plaques	plaque	NOUN
fnp-3025	146	8	show	show	VERB
fnp-3025	146	9	amyloid	amyloid	NOUN
fnp-3025	146	10	-	-	PUNCT
fnp-3025	146	11	type	type	NOUN
fnp-3025	146	12	birefringence	birefringence	NOUN
fnp-3025	146	13	after	after	ADP
fnp-3025	146	14	staining	stain	VERB
fnp-3025	146	15	with	with	ADP
fnp-3025	146	16	the	the	DET
fnp-3025	146	17	dye	dye	NOUN
fnp-3025	146	18	congo	congo	NOUN
fnp-3025	146	19	red	red	NOUN
fnp-3025	146	20	[	[	X
fnp-3025	146	21	125	125	NUM
fnp-3025	146	22	]	]	PUNCT
fnp-3025	146	23	,	,	PUNCT
fnp-3025	146	24	the	the	DET
fnp-3025	146	25	terms	term	NOUN
fnp-3025	146	26	‘	'	PUNCT
fnp-3025	146	27	congophilic	congophilic	ADJ
fnp-3025	146	28	plaques	plaque	NOUN
fnp-3025	146	29	’	'	PUNCT
fnp-3025	146	30	or	or	CCONJ
fnp-3025	146	31	‘	'	PUNCT
fnp-3025	146	32	amyloid	amyloid	NOUN
fnp-3025	146	33	plaques	plaque	NOUN
fnp-3025	146	34	’	'	PUNCT
fnp-3025	146	35	became	become	VERB
fnp-3025	146	36	common	common	ADJ
fnp-3025	146	37	.	.	PUNCT
fnp-3025	147	1	the	the	DET
fnp-3025	147	2	term	term	NOUN
fnp-3025	147	3	‘	'	PUNCT
fnp-3025	147	4	argyrophilic	argyrophilic	ADJ
fnp-3025	147	5	plaques	plaque	NOUN
fnp-3025	147	6	’	'	PUNCT
fnp-3025	147	7	also	also	ADV
fnp-3025	147	8	has	have	AUX
fnp-3025	147	9	been	be	AUX
fnp-3025	147	10	employed	employ	VERB
fnp-3025	147	11	,	,	PUNCT
fnp-3025	147	12	owing	owe	VERB
fnp-3025	147	13	to	to	ADP
fnp-3025	147	14	their	their	PRON
fnp-3025	147	15	detectability	detectability	NOUN
fnp-3025	147	16	by	by	ADP
fnp-3025	147	17	various	various	ADJ
fnp-3025	147	18	silver	silver	NOUN
fnp-3025	147	19	-	-	PUNCT
fnp-3025	147	20	based	base	VERB
fnp-3025	147	21	staining	staining	ADJ
fnp-3025	147	22	methods	method	NOUN
fnp-3025	147	23	[	[	X
fnp-3025	147	24	81	81	NUM
fnp-3025	147	25	]	]	PUNCT
fnp-3025	147	26	.	.	PUNCT
fnp-3025	148	1	other	other	ADJ
fnp-3025	148	2	labels	label	NOUN
fnp-3025	148	3	such	such	ADJ
fnp-3025	148	4	as	as	ADP
fnp-3025	148	5	‘	'	PUNCT
fnp-3025	148	6	miliary	miliary	ADJ
fnp-3025	148	7	plaques	plaque	NOUN
fnp-3025	148	8	’	'	PUNCT
fnp-3025	148	9	,	,	PUNCT
fnp-3025	148	10	‘	'	PUNCT
fnp-3025	148	11	drusen’,6	drusen’,6	VERB
fnp-3025	148	12	and	and	CCONJ
fnp-3025	148	13	‘	'	PUNCT
fnp-3025	148	14	redlich	redlich	NOUN
fnp-3025	148	15	-	-	PUNCT
fnp-3025	148	16	fischer	fischer	PROPN
fnp-3025	148	17	plaques	plaque	NOUN
fnp-3025	148	18	’	'	PUNCT
fnp-3025	148	19	can	can	AUX
fnp-3025	148	20	be	be	AUX
fnp-3025	148	21	found	find	VERB
fnp-3025	148	22	in	in	ADP
fnp-3025	148	23	the	the	DET
fnp-3025	148	24	earlier	early	ADJ
fnp-3025	148	25	literature	literature	NOUN
fnp-3025	148	26	[	[	X
fnp-3025	148	27	116	116	NUM
fnp-3025	148	28	]	]	PUNCT
fnp-3025	148	29	.	.	PUNCT
fnp-3025	149	1	in	in	ADP
fnp-3025	149	2	1972	1972	NUM
fnp-3025	149	3	,	,	PUNCT
fnp-3025	149	4	wisniewski	wisniewski	PROPN
fnp-3025	149	5	and	and	CCONJ
fnp-3025	149	6	terry	terry	PROPN
fnp-3025	149	7	introduced	introduce	VERB
fnp-3025	149	8	the	the	DET
fnp-3025	149	9	term	term	NOUN
fnp-3025	149	10	‘	'	PUNCT
fnp-3025	149	11	neuritic	neuritic	ADJ
fnp-3025	149	12	plaques	plaque	NOUN
fnp-3025	149	13	’	'	PUNCT
fnp-3025	149	14	in	in	ADP
fnp-3025	149	15	recognition	recognition	NOUN
fnp-3025	149	16	of	of	ADP
fnp-3025	149	17	the	the	DET
fnp-3025	149	18	profusion	profusion	NOUN
fnp-3025	149	19	of	of	ADP
fnp-3025	149	20	abnormal	abnormal	ADJ
fnp-3025	149	21	neuronal	neuronal	ADJ
fnp-3025	149	22	processes	process	NOUN
fnp-3025	149	23	that	that	PRON
fnp-3025	149	24	invest	invest	VERB
fnp-3025	149	25	many	many	ADJ
fnp-3025	149	26	plaques	plaque	NOUN
fnp-3025	149	27	.	.	PUNCT
fnp-3025	150	1	with	with	ADP
fnp-3025	150	2	the	the	DET
fnp-3025	150	3	identification	identification	NOUN
fnp-3025	150	4	of	of	ADP
fnp-3025	150	5	the	the	DET
fnp-3025	150	6	aβ	aβ	NOUN
fnp-3025	150	7	protein	protein	NOUN
fnp-3025	150	8	in	in	ADP
fnp-3025	150	9	plaques	plaque	NOUN
fnp-3025	150	10	,	,	PUNCT
fnp-3025	150	11	the	the	DET
fnp-3025	150	12	term	term	NOUN
fnp-3025	150	13	‘	'	PUNCT
fnp-3025	150	14	aβ	aβ	DET
fnp-3025	150	15	plaques	plaque	NOUN
fnp-3025	150	16	’	'	PUNCT
fnp-3025	150	17	is	be	AUX
fnp-3025	150	18	increasingly	increasingly	ADV
fnp-3025	150	19	common	common	ADJ
fnp-3025	150	20	.	.	PUNCT
fnp-3025	151	1	for	for	ADP
fnp-3025	151	2	the	the	DET
fnp-3025	151	3	following	follow	VERB
fnp-3025	151	4	reasons	reason	NOUN
fnp-3025	151	5	,	,	PUNCT
fnp-3025	151	6	‘	'	PUNCT
fnp-3025	151	7	aβ	aβ	DET
fnp-3025	151	8	plaques	plaque	NOUN
fnp-3025	151	9	’	'	PUNCT
fnp-3025	151	10	is	be	AUX
fnp-3025	151	11	recommended	recommend	VERB
fnp-3025	151	12	as	as	ADP
fnp-3025	151	13	the	the	DET
fnp-3025	151	14	inclusive	inclusive	ADJ
fnp-3025	151	15	term	term	NOUN
fnp-3025	151	16	that	that	PRON
fnp-3025	151	17	succinctly	succinctly	ADV
fnp-3025	151	18	encompasses	encompass	VERB
fnp-3025	151	19	the	the	DET
fnp-3025	151	20	multiplicity	multiplicity	NOUN
fnp-3025	151	21	of	of	ADP
fnp-3025	151	22	these	these	DET
fnp-3025	151	23	lesions	lesion	NOUN
fnp-3025	151	24	under	under	ADP
fnp-3025	151	25	the	the	DET
fnp-3025	151	26	umbrella	umbrella	NOUN
fnp-3025	151	27	of	of	ADP
fnp-3025	151	28	their	their	PRON
fnp-3025	151	29	shared	share	VERB
fnp-3025	151	30	feature	feature	NOUN
fnp-3025	151	31	aβ	aβ	ADP
fnp-3025	151	32	deposition:7	deposition:7	PROPN
fnp-3025	151	33	1	1	NUM
fnp-3025	151	34	)	)	PUNCT
fnp-3025	151	35	aβ	aβ	NOUN
fnp-3025	151	36	is	be	AUX
fnp-3025	151	37	present	present	ADJ
fnp-3025	151	38	in	in	ADP
fnp-3025	151	39	all	all	PRON
fnp-3025	151	40	of	of	ADP
fnp-3025	151	41	the	the	DET
fnp-3025	151	42	plaques	plaque	NOUN
fnp-3025	151	43	that	that	PRON
fnp-3025	151	44	are	be	AUX
fnp-3025	151	45	linked	link	VERB
fnp-3025	151	46	to	to	ADP
fnp-3025	151	47	‘	'	PUNCT
fnp-3025	151	48	normal	normal	ADJ
fnp-3025	151	49	’	'	PUNCT
fnp-3025	151	50	aging	aging	NOUN
fnp-3025	151	51	and	and	CCONJ
fnp-3025	151	52	ad	ad	NOUN
fnp-3025	151	53	,	,	PUNCT
fnp-3025	151	54	regardless	regardless	ADV
fnp-3025	151	55	of	of	ADP
fnp-3025	151	56	size	size	NOUN
fnp-3025	151	57	,	,	PUNCT
fnp-3025	151	58	shape	shape	NOUN
fnp-3025	151	59	,	,	PUNCT
fnp-3025	151	60	aggregation	aggregation	NOUN
fnp-3025	151	61	state	state	NOUN
fnp-3025	151	62	,	,	PUNCT
fnp-3025	151	63	location	location	NOUN
fnp-3025	151	64	,	,	PUNCT
fnp-3025	151	65	or	or	CCONJ
fnp-3025	151	66	overall	overall	ADJ
fnp-3025	151	67	composition	composition	NOUN
fnp-3025	151	68	.	.	PUNCT
fnp-3025	152	1	2	2	X
fnp-3025	152	2	)	)	PUNCT
fnp-3025	152	3	the	the	DET
fnp-3025	152	4	term	term	NOUN
fnp-3025	152	5	‘	'	PUNCT
fnp-3025	152	6	senile	senile	NOUN
fnp-3025	152	7	’	'	PUNCT
fnp-3025	152	8	is	be	AUX
fnp-3025	152	9	vague	vague	ADJ
fnp-3025	152	10	and	and	CCONJ
fnp-3025	152	11	arbitrary	arbitrary	ADJ
fnp-3025	152	12	,	,	PUNCT
fnp-3025	152	13	and	and	CCONJ
fnp-3025	152	14	not	not	PART
fnp-3025	152	15	all	all	DET
fnp-3025	152	16	plaques	plaque	NOUN
fnp-3025	152	17	occur	occur	VERB
fnp-3025	152	18	in	in	ADP
fnp-3025	152	19	‘	'	PUNCT
fnp-3025	152	20	senile	senile	ADJ
fnp-3025	152	21	’	'	PUNCT
fnp-3025	152	22	humans	human	NOUN
fnp-3025	152	23	.	.	PUNCT
fnp-3025	153	1	although	although	SCONJ
fnp-3025	153	2	aβ	aβ	PRON
fnp-3025	153	3	plaques	plaque	NOUN
fnp-3025	153	4	become	become	VERB
fnp-3025	153	5	more	more	ADV
fnp-3025	153	6	common	common	ADJ
fnp-3025	153	7	at	at	ADP
fnp-3025	153	8	older	old	ADJ
fnp-3025	153	9	ages	age	NOUN
fnp-3025	153	10	,	,	PUNCT
fnp-3025	153	11	they	they	PRON
fnp-3025	153	12	can	can	AUX
fnp-3025	153	13	emerge	emerge	VERB
fnp-3025	153	14	in	in	ADP
fnp-3025	153	15	the	the	DET
fnp-3025	153	16	4th	4th	ADJ
fnp-3025	153	17	decade	decade	NOUN
fnp-3025	153	18	of	of	ADP
fnp-3025	153	19	life	life	NOUN
fnp-3025	153	20	or	or	CCONJ
fnp-3025	153	21	earlier	early	ADV
fnp-3025	153	22	,	,	PUNCT
fnp-3025	153	23	especially	especially	ADV
fnp-3025	153	24	in	in	ADP
fnp-3025	153	25	people	people	NOUN
fnp-3025	153	26	with	with	ADP
fnp-3025	153	27	some	some	DET
fnp-3025	153	28	autosomal	autosomal	ADJ
fnp-3025	153	29	dominant	dominant	ADJ
fnp-3025	153	30	forms	form	NOUN
fnp-3025	153	31	of	of	ADP
fnp-3025	153	32	ad	ad	NOUN
fnp-3025	153	33	[	[	X
fnp-3025	153	34	126].8	126].8	NOUN
fnp-3025	153	35	3	3	NUM
fnp-3025	153	36	)	)	PUNCT
fnp-3025	153	37	plaques	plaque	NOUN
fnp-3025	153	38	that	that	PRON
fnp-3025	153	39	are	be	AUX
fnp-3025	153	40	structurally	structurally	ADV
fnp-3025	153	41	similar	similar	ADJ
fnp-3025	153	42	to	to	ADP
fnp-3025	153	43	aβ	aβ	PRON
fnp-3025	153	44	plaques	plaque	NOUN
fnp-3025	153	45	occur	occur	VERB
fnp-3025	153	46	in	in	ADP
fnp-3025	153	47	other	other	ADJ
fnp-3025	153	48	neurodegenerative	neurodegenerative	ADJ
fnp-3025	153	49	disorders	disorder	NOUN
fnp-3025	153	50	,	,	PUNCT
fnp-3025	153	51	yet	yet	CCONJ
fnp-3025	153	52	these	these	DET
fnp-3025	153	53	result	result	VERB
fnp-3025	153	54	from	from	ADP
fnp-3025	153	55	the	the	DET
fnp-3025	153	56	misfolding	misfolding	NOUN
fnp-3025	153	57	and	and	CCONJ
fnp-3025	153	58	aggregation	aggregation	NOUN
fnp-3025	153	59	of	of	ADP
fnp-3025	153	60	different	different	ADJ
fnp-3025	153	61	proteins	protein	NOUN
fnp-3025	153	62	.	.	PUNCT
fnp-3025	154	1	such	such	ADJ
fnp-3025	154	2	plaque	plaque	NOUN
fnp-3025	154	3	-	-	PUNCT
fnp-3025	154	4	forming	form	VERB
fnp-3025	154	5	proteins	protein	NOUN
fnp-3025	154	6	include	include	VERB
fnp-3025	154	7	the	the	DET
fnp-3025	154	8	prion	prion	NOUN
fnp-3025	154	9	protein	protein	NOUN
fnp-3025	154	10	(	(	PUNCT
fnp-3025	154	11	prp	prp	PROPN
fnp-3025	154	12	)	)	PUNCT
fnp-3025	154	13	in	in	ADP
fnp-3025	154	14	certain	certain	ADJ
fnp-3025	154	15	spongiform	spongiform	NOUN
fnp-3025	154	16	encephalopathies	encephalopathy	NOUN
fnp-3025	154	17	[	[	X
fnp-3025	154	18	127	127	NUM
fnp-3025	154	19	,	,	PUNCT
fnp-3025	154	20	128	128	NUM
fnp-3025	154	21	]	]	PUNCT
fnp-3025	154	22	,	,	PUNCT
fnp-3025	154	23	the	the	DET
fnp-3025	154	24	abri	abri	ADJ
fnp-3025	154	25	protein	protein	NOUN
fnp-3025	154	26	in	in	ADP
fnp-3025	154	27	familial	familial	ADJ
fnp-3025	154	28	british	british	ADJ
fnp-3025	154	29	dementia	dementia	NOUN
fnp-3025	154	30	[	[	X
fnp-3025	154	31	129	129	NUM
fnp-3025	154	32	,	,	PUNCT
fnp-3025	154	33	130	130	NUM
fnp-3025	154	34	]	]	PUNCT
fnp-3025	154	35	,	,	PUNCT
fnp-3025	154	36	and	and	CCONJ
fnp-3025	154	37	the	the	DET
fnp-3025	154	38	adan	adan	PROPN
fnp-3025	154	39	protein	protein	NOUN
fnp-3025	154	40	in	in	ADP
fnp-3025	154	41	familial	familial	ADJ
fnp-3025	154	42	danish	danish	ADJ
fnp-3025	154	43	dementia	dementia	NOUN
fnp-3025	154	44	[	[	X
fnp-3025	154	45	131	131	NUM
fnp-3025	154	46	,	,	PUNCT
fnp-3025	154	47	132	132	NUM
fnp-3025	154	48	]	]	PUNCT
fnp-3025	154	49	.	.	PUNCT
fnp-3025	155	1	4	4	X
fnp-3025	155	2	)	)	PUNCT
fnp-3025	155	3	not	not	PART
fnp-3025	155	4	all	all	PRON
fnp-3025	155	5	aβ	aβ	DET
fnp-3025	155	6	deposits	deposit	NOUN
fnp-3025	155	7	incorporate	incorporate	VERB
fnp-3025	155	8	abnormal	abnormal	ADJ
fnp-3025	155	9	neurites	neurite	NOUN
fnp-3025	155	10	,	,	PUNCT
fnp-3025	155	11	which	which	PRON
fnp-3025	155	12	often	often	ADV
fnp-3025	155	13	are	be	AUX
fnp-3025	155	14	sparse	sparse	ADJ
fnp-3025	155	15	or	or	CCONJ
fnp-3025	155	16	absent	absent	ADJ
fnp-3025	155	17	in	in	ADP
fnp-3025	155	18	diffuse	diffuse	ADJ
fnp-3025	155	19	plaques	plaque	NOUN
fnp-3025	156	1	[	[	X
fnp-3025	156	2	133	133	NUM
fnp-3025	156	3	]	]	PUNCT
fnp-3025	156	4	including	include	VERB
fnp-3025	156	5	cotton	cotton	NOUN
fnp-3025	156	6	-	-	PUNCT
fnp-3025	156	7	wool	wool	NOUN
fnp-3025	156	8	plaques	plaque	NOUN
fnp-3025	157	1	[	[	X
fnp-3025	157	2	90	90	NUM
fnp-3025	157	3	,	,	PUNCT
fnp-3025	157	4	93	93	NUM
fnp-3025	157	5	,	,	PUNCT
fnp-3025	157	6	134	134	NUM
fnp-3025	157	7	]	]	PUNCT
fnp-3025	157	8	(	(	PUNCT
fnp-3025	157	9	see	see	VERB
fnp-3025	157	10	below	below	ADV
fnp-3025	157	11	)	)	PUNCT
fnp-3025	157	12	.	.	PUNCT
fnp-3025	158	1	the	the	DET
fnp-3025	158	2	term	term	NOUN
fnp-3025	158	3	‘	'	PUNCT
fnp-3025	158	4	neuritic	neuritic	ADJ
fnp-3025	158	5	plaques	plaque	NOUN
fnp-3025	158	6	’	'	PUNCT
fnp-3025	158	7	is	be	AUX
fnp-3025	158	8	suitable	suitable	ADJ
fnp-3025	158	9	for	for	ADP
fnp-3025	158	10	the	the	DET
fnp-3025	158	11	lesions	lesion	NOUN
fnp-3025	158	12	that	that	PRON
fnp-3025	158	13	contain	contain	VERB
fnp-3025	158	14	neurites	neurite	NOUN
fnp-3025	158	15	,	,	PUNCT
fnp-3025	158	16	but	but	CCONJ
fnp-3025	158	17	these	these	PRON
fnp-3025	158	18	are	be	AUX
fnp-3025	158	19	only	only	ADV
fnp-3025	158	20	a	a	DET
fnp-3025	158	21	subset	subset	NOUN
fnp-3025	158	22	of	of	ADP
fnp-3025	158	23	the	the	DET
fnp-3025	158	24	entire	entire	ADJ
fnp-3025	158	25	family	family	NOUN
fnp-3025	158	26	of	of	ADP
fnp-3025	158	27	aβ	aβ	DET
fnp-3025	158	28	plaques	plaque	NOUN
fnp-3025	158	29	.	.	PUNCT
fnp-3025	159	1	5	5	X
fnp-3025	159	2	)	)	PUNCT
fnp-3025	159	3	the	the	DET
fnp-3025	159	4	aβ	aβ	NOUN
fnp-3025	159	5	in	in	ADP
fnp-3025	159	6	plaques	plaque	NOUN
fnp-3025	159	7	does	do	AUX
fnp-3025	159	8	not	not	PART
fnp-3025	159	9	always	always	ADV
fnp-3025	159	10	meet	meet	VERB
fnp-3025	159	11	all	all	PRON
fnp-3025	159	12	of	of	ADP
fnp-3025	159	13	the	the	DET
fnp-3025	159	14	criteria	criterion	NOUN
fnp-3025	159	15	for	for	ADP
fnp-3025	159	16	amyloid	amyloid	NOUN
fnp-3025	159	17	[	[	X
fnp-3025	159	18	6	6	NUM
fnp-3025	159	19	]	]	PUNCT
fnp-3025	159	20	(	(	PUNCT
fnp-3025	159	21	see	see	VERB
fnp-3025	159	22	section	section	NOUN
fnp-3025	159	23	1.2	1.2	NUM
fnp-3025	159	24	)	)	PUNCT
fnp-3025	159	25	.	.	PUNCT
fnp-3025	160	1	many	many	ADJ
fnp-3025	160	2	diffuse	diffuse	VERB
fnp-3025	160	3	aβ	aβ	NUM
fnp-3025	160	4	deposits	deposit	NOUN
fnp-3025	160	5	in	in	ADP
fnp-3025	160	6	the	the	DET
fnp-3025	160	7	aging	age	VERB
fnp-3025	160	8	brain	brain	NOUN
fnp-3025	160	9	do	do	AUX
fnp-3025	160	10	not	not	PART
fnp-3025	160	11	show	show	VERB
fnp-3025	160	12	birefringence	birefringence	NOUN
fnp-3025	160	13	after	after	ADP
fnp-3025	160	14	staining	stain	VERB
fnp-3025	160	15	with	with	ADP
fnp-3025	160	16	congo	congo	NOUN
fnp-3025	160	17	red	red	ADJ
fnp-3025	160	18	.	.	PUNCT
fnp-3025	161	1	in	in	ADP
fnp-3025	161	2	addition	addition	NOUN
fnp-3025	161	3	,	,	PUNCT
fnp-3025	161	4	large	large	ADJ
fnp-3025	161	5	,	,	PUNCT
fnp-3025	161	6	cotton	cotton	NOUN
fnp-3025	161	7	-	-	PUNCT
fnp-3025	161	8	wool	wool	NOUN
fnp-3025	161	9	aβ	aβ	ADP
fnp-3025	161	10	plaques	plaque	NOUN
fnp-3025	161	11	lacking	lack	VERB
fnp-3025	161	12	amyloid	amyloid	NOUN
fnp-3025	161	13	cores	core	NOUN
fnp-3025	161	14	are	be	AUX
fnp-3025	161	15	abundant	abundant	ADJ
fnp-3025	161	16	in	in	ADP
fnp-3025	161	17	certain	certain	ADJ
fnp-3025	161	18	presenilin-1	presenilin-1	NUM
fnp-3025	161	19	mutant	mutant	ADJ
fnp-3025	161	20	cases	case	NOUN
fnp-3025	161	21	of	of	ADP
fnp-3025	161	22	autosomal	autosomal	ADJ
fnp-3025	161	23	dominant	dominant	ADJ
fnp-3025	161	24	ad	ad	NOUN
fnp-3025	161	25	[	[	X
fnp-3025	161	26	90	90	NUM
fnp-3025	161	27	,	,	PUNCT
fnp-3025	161	28	91	91	NUM
fnp-3025	161	29	,	,	PUNCT
fnp-3025	161	30	93	93	NUM
fnp-3025	161	31	,	,	PUNCT
fnp-3025	161	32	94	94	NUM
fnp-3025	161	33	,	,	PUNCT
fnp-3025	161	34	134	134	NUM
fnp-3025	161	35	]	]	PUNCT
fnp-3025	161	36	and	and	CCONJ
fnp-3025	161	37	in	in	ADP
fnp-3025	161	38	some	some	DET
fnp-3025	161	39	non	non	ADJ
fnp-3025	161	40	-	-	ADJ
fnp-3025	161	41	familial	familial	ADJ
fnp-3025	161	42	cases	case	NOUN
fnp-3025	161	43	[	[	X
fnp-3025	161	44	92	92	NUM
fnp-3025	161	45	]	]	PUNCT
fnp-3025	161	46	.	.	PUNCT
fnp-3025	162	1	(	(	PUNCT
fnp-3025	162	2	the	the	DET
fnp-3025	162	3	aβ	aβ	NOUN
fnp-3025	162	4	in	in	ADP
fnp-3025	162	5	non	non	ADJ
fnp-3025	162	6	-	-	ADJ
fnp-3025	162	7	amyloid	amyloid	ADJ
fnp-3025	162	8	plaques	plaque	NOUN
fnp-3025	162	9	from	from	ADP
fnp-3025	162	10	some	some	DET
fnp-3025	162	11	presenilin-1	presenilin-1	NUM
fnp-3025	162	12	mutant	mutant	ADJ
fnp-3025	162	13	cases	case	NOUN
fnp-3025	162	14	is	be	AUX
fnp-3025	162	15	unusual	unusual	ADJ
fnp-3025	162	16	in	in	SCONJ
fnp-3025	162	17	that	that	SCONJ
fnp-3025	162	18	it	it	PRON
fnp-3025	162	19	consists	consist	VERB
fnp-3025	162	20	mostly	mostly	ADV
fnp-3025	162	21	of	of	ADP
fnp-3025	162	22	n	n	ADV
fnp-3025	162	23	-	-	PUNCT
fnp-3025	162	24	terminally	terminally	ADV
fnp-3025	162	25	truncated	truncate	VERB
fnp-3025	162	26	aβ	aβ	NOUN
fnp-3025	163	1	[	[	X
fnp-3025	163	2	94	94	NUM
fnp-3025	163	3	]	]	PUNCT
fnp-3025	163	4	,	,	PUNCT
fnp-3025	163	5	as	as	SCONJ
fnp-3025	163	6	do	do	AUX
fnp-3025	163	7	diffuse	diffuse	VERB
fnp-3025	163	8	deposits	deposit	NOUN
fnp-3025	163	9	in	in	ADP
fnp-3025	163	10	the	the	DET
fnp-3025	163	11	cerebellum	cerebellum	NOUN
fnp-3025	163	12	in	in	ADP
fnp-3025	163	13	ad	ad	NOUN
fnp-3025	164	1	[	[	X
fnp-3025	164	2	135	135	NUM
fnp-3025	164	3	]	]	PUNCT
fnp-3025	164	4	and	and	CCONJ
fnp-3025	164	5	down	down	ADP
fnp-3025	164	6	syndrome	syndrome	NOUN
fnp-3025	165	1	[	[	X
fnp-3025	165	2	135	135	NUM
fnp-3025	165	3	,	,	PUNCT
fnp-3025	165	4	136	136	NUM
fnp-3025	165	5	]	]	PUNCT
fnp-3025	165	6	)	)	PUNCT
fnp-3025	165	7	.	.	PUNCT
fnp-3025	166	1	the	the	DET
fnp-3025	166	2	term	term	NOUN
fnp-3025	166	3	‘	'	PUNCT
fnp-3025	166	4	amyloid	amyloid	NOUN
fnp-3025	166	5	plaques	plaque	NOUN
fnp-3025	166	6	’	'	PUNCT
fnp-3025	166	7	,	,	PUNCT
fnp-3025	166	8	like	like	ADP
fnp-3025	166	9	‘	'	PUNCT
fnp-3025	166	10	neuritic	neuritic	ADJ
fnp-3025	166	11	plaques	plaque	NOUN
fnp-3025	166	12	’	'	PUNCT
fnp-3025	166	13	,	,	PUNCT
fnp-3025	166	14	is	be	AUX
fnp-3025	166	15	appropriate	appropriate	ADJ
fnp-3025	166	16	for	for	ADP
fnp-3025	166	17	a	a	DET
fnp-3025	166	18	subgroup	subgroup	NOUN
fnp-3025	166	19	of	of	ADP
fnp-3025	166	20	the	the	DET
fnp-3025	166	21	lesions	lesion	NOUN
fnp-3025	166	22	,	,	PUNCT
fnp-3025	166	23	but	but	CCONJ
fnp-3025	166	24	the	the	DET
fnp-3025	166	25	universal	universal	ADJ
fnp-3025	166	26	constituent	constituent	NOUN
fnp-3025	166	27	is	be	AUX
fnp-3025	166	28	aβ	aβ	ADP
fnp-3025	166	29	,	,	PUNCT
fnp-3025	166	30	whether	whether	SCONJ
fnp-3025	166	31	it	it	PRON
fnp-3025	166	32	is	be	AUX
fnp-3025	166	33	in	in	ADP
fnp-3025	166	34	the	the	DET
fnp-3025	166	35	form	form	NOUN
fnp-3025	166	36	of	of	ADP
fnp-3025	166	37	amyloid	amyloid	NOUN
fnp-3025	166	38	or	or	CCONJ
fnp-3025	166	39	not	not	PART
fnp-3025	166	40	;	;	PUNCT
fnp-3025	166	41	hence	hence	ADV
fnp-3025	166	42	,	,	PUNCT
fnp-3025	166	43	more	more	ADV
fnp-3025	166	44	precise	precise	ADJ
fnp-3025	166	45	designations	designation	NOUN
fnp-3025	166	46	of	of	ADP
fnp-3025	166	47	plaque	plaque	NOUN
fnp-3025	166	48	subtypes	subtype	NOUN
fnp-3025	166	49	would	would	AUX
fnp-3025	166	50	be	be	AUX
fnp-3025	166	51	,	,	PUNCT
fnp-3025	166	52	for	for	ADP
fnp-3025	166	53	example	example	NOUN
fnp-3025	166	54	,	,	PUNCT
fnp-3025	166	55	‘	'	PUNCT
fnp-3025	166	56	aβ	aβ	PRON
fnp-3025	166	57	-	-	PUNCT
fnp-3025	166	58	amyloid	amyloid	NOUN
fnp-3025	166	59	plaques	plaque	NOUN
fnp-3025	166	60	’	'	PUNCT
fnp-3025	166	61	and	and	CCONJ
fnp-3025	166	62	‘	'	PUNCT
fnp-3025	166	63	neuritic	neuritic	ADJ
fnp-3025	166	64	aβ	aβ	NOUN
fnp-3025	166	65	plaques	plaque	NOUN
fnp-3025	166	66	’	'	PUNCT
fnp-3025	166	67	.	.	PUNCT
fnp-3025	167	1	note	note	VERB
fnp-3025	167	2	that	that	SCONJ
fnp-3025	167	3	‘	'	PUNCT
fnp-3025	167	4	diffuse	diffuse	ADJ
fnp-3025	167	5	plaques	plaque	NOUN
fnp-3025	167	6	’	'	PUNCT
fnp-3025	167	7	here	here	ADV
fnp-3025	167	8	refers	refer	VERB
fnp-3025	167	9	to	to	ADP
fnp-3025	167	10	the	the	DET
fnp-3025	167	11	fact	fact	NOUN
fnp-3025	167	12	that	that	SCONJ
fnp-3025	167	13	the	the	DET
fnp-3025	167	14	aβ	aβ	NOUN
fnp-3025	167	15	accumulation	accumulation	NOUN
fnp-3025	167	16	is	be	AUX
fnp-3025	167	17	‘	'	PUNCT
fnp-3025	167	18	widely	widely	ADV
fnp-3025	167	19	spread	spread	ADJ
fnp-3025	167	20	or	or	CCONJ
fnp-3025	167	21	scattered	scatter	VERB
fnp-3025	167	22	;	;	PUNCT
fnp-3025	167	23	not	not	PART
fnp-3025	167	24	concentrated	concentrate	VERB
fnp-3025	167	25	’	'	PUNCT
fnp-3025	168	1	[	[	X
fnp-3025	168	2	137	137	NUM
fnp-3025	168	3	]	]	PUNCT
fnp-3025	168	4	,	,	PUNCT
fnp-3025	168	5	without	without	ADP
fnp-3025	168	6	consideration	consideration	NOUN
fnp-3025	168	7	of	of	ADP
fnp-3025	168	8	the	the	DET
fnp-3025	168	9	nature	nature	NOUN
fnp-3025	168	10	of	of	ADP
fnp-3025	168	11	the	the	DET
fnp-3025	168	12	aβ	aβ	NOUN
fnp-3025	168	13	deposits	deposit	NOUN
fnp-3025	168	14	,	,	PUNCT
fnp-3025	168	15	e.g.	e.g.	ADV
fnp-3025	168	16	,	,	PUNCT
fnp-3025	168	17	thread	thread	NOUN
fnp-3025	168	18	-	-	PUNCT
fnp-3025	168	19	like	like	NOUN
fnp-3025	168	20	or	or	CCONJ
fnp-3025	168	21	punctate	punctate	VERB
fnp-3025	168	22	.	.	PUNCT
fnp-3025	169	1	‘	'	PUNCT
fnp-3025	169	2	diffuse	diffuse	NOUN
fnp-3025	169	3	’	'	PUNCT
fnp-3025	169	4	thus	thus	ADV
fnp-3025	169	5	denotes	denote	VERB
fnp-3025	169	6	only	only	ADV
fnp-3025	169	7	the	the	DET
fnp-3025	169	8	characteristics	characteristic	NOUN
fnp-3025	169	9	of	of	ADP
fnp-3025	169	10	the	the	DET
fnp-3025	169	11	aβ	aβ	NOUN
fnp-3025	169	12	deposits	deposit	NOUN
fnp-3025	169	13	,	,	PUNCT
fnp-3025	169	14	and	and	CCONJ
fnp-3025	169	15	not	not	PART
fnp-3025	169	16	the	the	DET
fnp-3025	169	17	dysmorphic	dysmorphic	ADJ
fnp-3025	169	18	neurites	neurite	NOUN
fnp-3025	169	19	or	or	CCONJ
fnp-3025	169	20	any	any	DET
fnp-3025	169	21	other	other	ADJ
fnp-3025	169	22	component	component	NOUN
fnp-3025	169	23	of	of	ADP
fnp-3025	169	24	the	the	DET
fnp-3025	169	25	plaques	plaque	NOUN
fnp-3025	169	26	.	.	PUNCT
fnp-3025	170	1	also	also	ADV
fnp-3025	170	2	,	,	PUNCT
fnp-3025	170	3	when	when	SCONJ
fnp-3025	170	4	analyzing	analyze	VERB
fnp-3025	170	5	aβ	aβ	ADP
fnp-3025	170	6	plaques	plaque	NOUN
fnp-3025	170	7	histologically	histologically	ADV
fnp-3025	170	8	,	,	PUNCT
fnp-3025	170	9	it	it	PRON
fnp-3025	170	10	is	be	AUX
fnp-3025	170	11	useful	useful	ADJ
fnp-3025	170	12	to	to	PART
fnp-3025	170	13	be	be	AUX
fnp-3025	170	14	cognizant	cognizant	ADJ
fnp-3025	170	15	of	of	ADP
fnp-3025	170	16	the	the	DET
fnp-3025	170	17	plane	plane	NOUN
fnp-3025	170	18	of	of	ADP
fnp-3025	170	19	section	section	NOUN
fnp-3025	170	20	,	,	PUNCT
fnp-3025	170	21	thickness	thickness	NOUN
fnp-3025	170	22	of	of	ADP
fnp-3025	170	23	the	the	DET
fnp-3025	170	24	tissue	tissue	NOUN
fnp-3025	170	25	,	,	PUNCT
fnp-3025	170	26	and	and	CCONJ
fnp-3025	170	27	the	the	DET
fnp-3025	170	28	limitations	limitation	NOUN
fnp-3025	170	29	of	of	ADP
fnp-3025	170	30	a	a	DET
fnp-3025	170	31	given	give	VERB
fnp-3025	170	32	staining	stain	VERB
fnp-3025	170	33	protocol	protocol	NOUN
fnp-3025	170	34	.	.	PUNCT
fnp-3025	171	1	plaques	plaque	NOUN
fnp-3025	171	2	are	be	AUX
fnp-3025	171	3	3	3	NUM
fnp-3025	171	4	-	-	PUNCT
fnp-3025	171	5	dimensional	dimensional	ADJ
fnp-3025	171	6	structures	structure	NOUN
fnp-3025	171	7	that	that	PRON
fnp-3025	171	8	,	,	PUNCT
fnp-3025	171	9	when	when	SCONJ
fnp-3025	171	10	large	large	ADJ
fnp-3025	171	11	enough	enough	ADV
fnp-3025	171	12	,	,	PUNCT
fnp-3025	171	13	are	be	AUX
fnp-3025	171	14	only	only	ADV
fnp-3025	171	15	partially	partially	ADV
fnp-3025	171	16	captured	capture	VERB
fnp-3025	171	17	in	in	ADP
fnp-3025	171	18	thin	thin	ADJ
fnp-3025	171	19	histologic	histologic	ADJ
fnp-3025	171	20	sections	section	NOUN
fnp-3025	171	21	(	(	PUNCT
fnp-3025	171	22	figure	figure	NOUN
fnp-3025	171	23	4	4	NUM
fnp-3025	171	24	)	)	PUNCT
fnp-3025	171	25	.	.	PUNCT
fnp-3025	172	1	furthermore	furthermore	ADV
fnp-3025	172	2	,	,	PUNCT
fnp-3025	172	3	different	different	ADJ
fnp-3025	172	4	stains	stain	NOUN
fnp-3025	172	5	recognize	recognize	VERB
fnp-3025	172	6	different	different	ADJ
fnp-3025	172	7	components	component	NOUN
fnp-3025	172	8	of	of	ADP
fnp-3025	172	9	plaques	plaque	NOUN
fnp-3025	172	10	.	.	PUNCT
fnp-3025	173	1	consequently	consequently	ADV
fnp-3025	173	2	,	,	PUNCT
fnp-3025	173	3	a	a	DET
fnp-3025	173	4	comprehensive	comprehensive	ADJ
fnp-3025	173	5	assessment	assessment	NOUN
fnp-3025	173	6	of	of	ADP
fnp-3025	173	7	plaques	plaque	NOUN
fnp-3025	173	8	requires	require	VERB
fnp-3025	173	9	their	their	PRON
fnp-3025	173	10	full	full	ADJ
fnp-3025	173	11	reconstruction	reconstruction	NOUN
fnp-3025	173	12	and	and	CCONJ
fnp-3025	173	13	the	the	DET
fnp-3025	173	14	application	application	NOUN
fnp-3025	173	15	of	of	ADP
fnp-3025	173	16	suitable	suitable	ADJ
fnp-3025	173	17	markers	marker	NOUN
fnp-3025	173	18	for	for	ADP
fnp-3025	173	19	potential	potential	ADJ
fnp-3025	173	20	components	component	NOUN
fnp-3025	173	21	.	.	PUNCT
fnp-3025	174	1	in	in	ADP
fnp-3025	174	2	congruence	congruence	NOUN
fnp-3025	174	3	with	with	ADP
fnp-3025	174	4	the	the	DET
fnp-3025	174	5	trend	trend	NOUN
fnp-3025	174	6	to	to	PART
fnp-3025	174	7	define	define	VERB
fnp-3025	174	8	ad	ad	NOUN
fnp-3025	174	9	according	accord	VERB
fnp-3025	174	10	to	to	ADP
fnp-3025	174	11	its	its	PRON
fnp-3025	174	12	molecular	molecular	ADJ
fnp-3025	174	13	underpinnings	underpinning	NOUN
fnp-3025	174	14	[	[	X
fnp-3025	174	15	109	109	NUM
fnp-3025	174	16	]	]	PUNCT
fnp-3025	174	17	,	,	PUNCT
fnp-3025	174	18	defining	define	VERB
fnp-3025	174	19	the	the	DET
fnp-3025	174	20	plaques	plaque	NOUN
fnp-3025	174	21	that	that	PRON
fnp-3025	174	22	occur	occur	VERB
fnp-3025	174	23	in	in	ADP
fnp-3025	174	24	aging	aging	NOUN
fnp-3025	174	25	and	and	CCONJ
fnp-3025	174	26	ad	ad	NOUN
fnp-3025	174	27	based	base	VERB
fnp-3025	174	28	on	on	ADP
fnp-3025	174	29	their	their	PRON
fnp-3025	174	30	principal	principal	ADJ
fnp-3025	174	31	proteinaceous	proteinaceous	ADJ
fnp-3025	174	32	component	component	NOUN
fnp-3025	174	33	unambiguously	unambiguously	ADV
fnp-3025	174	34	distinguishes	distinguish	VERB
fnp-3025	174	35	them	they	PRON
fnp-3025	174	36	from	from	ADP
fnp-3025	174	37	similar	similar	ADJ
fnp-3025	174	38	lesions	lesion	NOUN
fnp-3025	174	39	in	in	ADP
fnp-3025	174	40	other	other	ADJ
fnp-3025	174	41	disorders	disorder	NOUN
fnp-3025	174	42	.	.	PUNCT
fnp-3025	175	1	in	in	ADP
fnp-3025	175	2	addition	addition	NOUN
fnp-3025	175	3	,	,	PUNCT
fnp-3025	175	4	this	this	DET
fnp-3025	175	5	molecularly	molecularly	ADV
fnp-3025	175	6	grounded	ground	VERB
fnp-3025	175	7	moniker	moniker	NOUN
fnp-3025	175	8	explicitly	explicitly	ADV
fnp-3025	175	9	specifies	specify	VERB
fnp-3025	175	10	the	the	DET
fnp-3025	175	11	attribute	attribute	NOUN
fnp-3025	175	12	that	that	PRON
fnp-3025	175	13	defines	define	VERB
fnp-3025	175	14	these	these	DET
fnp-3025	175	15	plaques	plaque	NOUN
fnp-3025	175	16	as	as	ADP
fnp-3025	175	17	unique	unique	ADJ
fnp-3025	175	18	pathologic	pathologic	ADJ
fnp-3025	175	19	entities	entity	NOUN
fnp-3025	175	20	:	:	PUNCT
fnp-3025	175	21	the	the	DET
fnp-3025	175	22	misfolding	misfolding	ADJ
fnp-3025	175	23	and	and	CCONJ
fnp-3025	175	24	abnormal	abnormal	ADJ
fnp-3025	175	25	accumulation	accumulation	NOUN
fnp-3025	175	26	of	of	ADP
fnp-3025	175	27	the	the	DET
fnp-3025	175	28	aβ	aβ	NOUN
fnp-3025	175	29	protein	protein	NOUN
fnp-3025	175	30	.	.	PUNCT
fnp-3025	176	1	5	5	NUM
fnp-3025	176	2	‘	'	PUNCT
fnp-3025	176	3	plaque	plaque	NOUN
fnp-3025	176	4	(	(	PUNCT
fnp-3025	176	5	subject	subject	NOUN
fnp-3025	176	6	:	:	PUNCT
fnp-3025	176	7	medicine	medicine	NOUN
fnp-3025	176	8	and	and	CCONJ
fnp-3025	176	9	health	health	NOUN
fnp-3025	176	10	):	):	PUNCT
fnp-3025	176	11	any	any	DET
fnp-3025	176	12	small	small	ADJ
fnp-3025	176	13	patch	patch	NOUN
fnp-3025	176	14	or	or	CCONJ
fnp-3025	176	15	region	region	NOUN
fnp-3025	176	16	of	of	ADP
fnp-3025	176	17	abnormal	abnormal	ADJ
fnp-3025	176	18	tissue	tissue	NOUN
fnp-3025	176	19	within	within	ADP
fnp-3025	176	20	the	the	DET
fnp-3025	176	21	body	body	NOUN
fnp-3025	176	22	.	.	PUNCT
fnp-3025	177	1	see	see	VERB
fnp-3025	177	2	amyloid	amyloid	NOUN
fnp-3025	177	3	plaque	plaque	NOUN
fnp-3025	177	4	,	,	PUNCT
fnp-3025	177	5	gliosis	gliosis	NOUN
fnp-3025	177	6	.	.	PUNCT
fnp-3025	178	1	[	[	X
fnp-3025	178	2	from	from	SCONJ
fnp-3025	178	3	french	french	ADJ
fnp-3025	178	4	plaquer	plaquer	NOUN
fnp-3025	178	5	to	to	PART
fnp-3025	178	6	plate	plate	VERB
fnp-3025	178	7	,	,	PUNCT
fnp-3025	178	8	from	from	ADP
fnp-3025	178	9	middle	middle	PROPN
fnp-3025	178	10	dutch	dutch	PROPN
fnp-3025	178	11	placken	placken	VERB
fnp-3025	178	12	to	to	PART
fnp-3025	178	13	beat	beat	VERB
fnp-3025	178	14	metal	metal	NOUN
fnp-3025	178	15	]	]	PUNCT
fnp-3025	178	16	.	.	PUNCT
fnp-3025	178	17	’	'	PUNCT
fnp-3025	179	1	from	from	ADP
fnp-3025	179	2	:	:	PUNCT
fnp-3025	179	3	oxford	oxford	PROPN
fnp-3025	179	4	dictionary	dictionary	NOUN
fnp-3025	179	5	of	of	ADP
fnp-3025	179	6	word	word	NOUN
fnp-3025	179	7	origins	origin	NOUN
fnp-3025	179	8	:	:	PUNCT
fnp-3025	179	9	https://www.oxfordreference.com/view/10.1093/acref/9780199547920.001.0001/acref-9780199547920	https://www.oxfordreference.com/view/10.1093/acref/9780199547920.001.0001/acref-9780199547920	PROPN
fnp-3025	179	10	6	6	NUM
fnp-3025	179	11	note	note	NOUN
fnp-3025	179	12	that	that	SCONJ
fnp-3025	179	13	‘	'	PUNCT
fnp-3025	179	14	druse	druse	NOUN
fnp-3025	179	15	’	'	PUNCT
fnp-3025	179	16	(	(	PUNCT
fnp-3025	179	17	‘	'	PUNCT
fnp-3025	179	18	geode	geode	NOUN
fnp-3025	179	19	’	'	PUNCT
fnp-3025	179	20	)	)	PUNCT
fnp-3025	179	21	differs	differ	VERB
fnp-3025	179	22	from	from	ADP
fnp-3025	179	23	‘	'	PUNCT
fnp-3025	179	24	drüse	drüse	NOUN
fnp-3025	179	25	’	'	PUNCT
fnp-3025	179	26	(	(	PUNCT
fnp-3025	179	27	with	with	ADP
fnp-3025	179	28	umlaut	umlaut	NOUN
fnp-3025	179	29	)	)	PUNCT
fnp-3025	179	30	,	,	PUNCT
fnp-3025	179	31	which	which	PRON
fnp-3025	179	32	refers	refer	VERB
fnp-3025	179	33	to	to	ADP
fnp-3025	179	34	a	a	DET
fnp-3025	179	35	‘	'	PUNCT
fnp-3025	179	36	gland	gland	NOUN
fnp-3025	179	37	’	'	PUNCT
fnp-3025	179	38	.	.	PUNCT
fnp-3025	180	1	7	7	NUM
fnp-3025	180	2	because	because	SCONJ
fnp-3025	180	3	‘	'	PUNCT
fnp-3025	180	4	aβ	aβ	NUM
fnp-3025	180	5	’	'	PUNCT
fnp-3025	180	6	and	and	CCONJ
fnp-3025	180	7	‘	'	PUNCT
fnp-3025	180	8	plaque	plaque	NOUN
fnp-3025	180	9	’	'	PUNCT
fnp-3025	180	10	are	be	AUX
fnp-3025	180	11	both	both	DET
fnp-3025	180	12	nouns	noun	NOUN
fnp-3025	180	13	,	,	PUNCT
fnp-3025	180	14	they	they	PRON
fnp-3025	180	15	could	could	AUX
fnp-3025	180	16	be	be	AUX
fnp-3025	180	17	connected	connect	VERB
fnp-3025	180	18	by	by	ADP
fnp-3025	180	19	a	a	DET
fnp-3025	180	20	hyphen	hyphen	ADV
fnp-3025	180	21	(	(	PUNCT
fnp-3025	180	22	aβ	aβ	NOUN
fnp-3025	180	23	-	-	PUNCT
fnp-3025	180	24	plaque	plaque	NOUN
fnp-3025	180	25	)	)	PUNCT
fnp-3025	180	26	.	.	PUNCT
fnp-3025	181	1	i	i	PRON
fnp-3025	181	2	have	have	AUX
fnp-3025	181	3	chosen	choose	VERB
fnp-3025	181	4	not	not	PART
fnp-3025	181	5	to	to	PART
fnp-3025	181	6	include	include	VERB
fnp-3025	181	7	the	the	DET
fnp-3025	181	8	hyphen	hyphen	ADV
fnp-3025	181	9	(	(	PUNCT
fnp-3025	181	10	the	the	DET
fnp-3025	181	11	‘	'	PUNCT
fnp-3025	181	12	open	open	ADJ
fnp-3025	181	13	form	form	NOUN
fnp-3025	181	14	’	'	PUNCT
fnp-3025	181	15	)	)	PUNCT
fnp-3025	181	16	in	in	ADP
fnp-3025	181	17	order	order	NOUN
fnp-3025	181	18	to	to	PART
fnp-3025	181	19	simplify	simplify	VERB
fnp-3025	181	20	usage	usage	NOUN
fnp-3025	181	21	.	.	PUNCT
fnp-3025	182	1	in	in	ADP
fnp-3025	182	2	some	some	DET
fnp-3025	182	3	cases	case	NOUN
fnp-3025	182	4	(	(	PUNCT
fnp-3025	182	5	such	such	ADJ
fnp-3025	182	6	as	as	ADP
fnp-3025	182	7	aβ	aβ	NOUN
fnp-3025	182	8	-	-	PUNCT
fnp-3025	182	9	caa	caa	NOUN
fnp-3025	182	10	&	&	CCONJ
fnp-3025	182	11	aβ	aβ	NOUN
fnp-3025	182	12	-	-	PUNCT
fnp-3025	182	13	oligomers	oligomer	NOUN
fnp-3025	182	14	)	)	PUNCT
fnp-3025	182	15	,	,	PUNCT
fnp-3025	182	16	i	i	PRON
fnp-3025	182	17	have	have	AUX
fnp-3025	182	18	retained	retain	VERB
fnp-3025	182	19	the	the	DET
fnp-3025	182	20	hyphen	hyphen	NOUN
fnp-3025	182	21	for	for	ADP
fnp-3025	182	22	clarity	clarity	NOUN
fnp-3025	182	23	.	.	PUNCT
fnp-3025	183	1	8	8	NUM
fnp-3025	183	2	w.h	w.h	PROPN
fnp-3025	183	3	.	.	PROPN
fnp-3025	183	4	mcmenemey	mcmenemey	PROPN
fnp-3025	183	5	opined	opine	VERB
fnp-3025	183	6	in	in	ADP
fnp-3025	183	7	1963	1963	NUM
fnp-3025	183	8	:	:	PUNCT
fnp-3025	183	9	‘	'	PUNCT
fnp-3025	183	10	...	...	PUNCT
fnp-3025	183	11	the	the	DET
fnp-3025	183	12	structures	structure	NOUN
fnp-3025	183	13	first	first	ADV
fnp-3025	183	14	observed	observe	VERB
fnp-3025	183	15	by	by	ADP
fnp-3025	183	16	blocq	blocq	NOUN
fnp-3025	183	17	&	&	CCONJ
fnp-3025	183	18	marinesco	marinesco	PROPN
fnp-3025	183	19	(	(	PUNCT
fnp-3025	183	20	1892	1892	NUM
fnp-3025	183	21	)	)	PUNCT
fnp-3025	183	22	and	and	CCONJ
fnp-3025	183	23	thought	think	VERB
fnp-3025	183	24	by	by	ADP
fnp-3025	183	25	them	they	PRON
fnp-3025	183	26	to	to	PART
fnp-3025	183	27	be	be	AUX
fnp-3025	183	28	nodules	nodule	NOUN
fnp-3025	183	29	of	of	ADP
fnp-3025	183	30	glial	glial	ADJ
fnp-3025	183	31	sclerosis	sclerosis	NOUN
fnp-3025	183	32	were	be	AUX
fnp-3025	183	33	called	call	VERB
fnp-3025	183	34	by	by	ADP
fnp-3025	183	35	simchowicz	simchowicz	NOUN
fnp-3025	183	36	(	(	PUNCT
fnp-3025	183	37	1910	1910	NUM
fnp-3025	183	38	)	)	PUNCT
fnp-3025	183	39	‘	'	PUNCT
fnp-3025	183	40	senile	senile	ADJ
fnp-3025	183	41	plaques	plaque	NOUN
fnp-3025	183	42	’	'	PUNCT
fnp-3025	183	43	an	an	DET
fnp-3025	183	44	unfortunate	unfortunate	ADJ
fnp-3025	183	45	choice	choice	NOUN
fnp-3025	183	46	of	of	ADP
fnp-3025	183	47	name	name	NOUN
fnp-3025	183	48	for	for	ADP
fnp-3025	183	49	it	it	PRON
fnp-3025	183	50	has	have	AUX
fnp-3025	183	51	coloured	colour	VERB
fnp-3025	183	52	our	our	PRON
fnp-3025	183	53	thinking	thinking	NOUN
fnp-3025	183	54	for	for	ADP
fnp-3025	183	55	the	the	DET
fnp-3025	183	56	past	past	ADJ
fnp-3025	183	57	fifty	fifty	NUM
fnp-3025	183	58	years	year	NOUN
fnp-3025	183	59	’	'	PUNCT
fnp-3025	184	1	[	[	X
fnp-3025	184	2	reference	reference	NOUN
fnp-3025	184	3	509	509	NUM
fnp-3025	184	4	]	]	PUNCT
fnp-3025	184	5	.	.	PUNCT
fnp-3025	185	1	4	4	X
fnp-3025	185	2	.	.	X
fnp-3025	185	3	the	the	DET
fnp-3025	185	4	anatomic	anatomic	ADJ
fnp-3025	185	5	distribution	distribution	NOUN
fnp-3025	185	6	of	of	ADP
fnp-3025	185	7	aβ	aβ	PRON
fnp-3025	185	8	plaques	plaque	NOUN
fnp-3025	185	9	4.1	4.1	NUM
fnp-3025	185	10	histology	histology	NOUN
fnp-3025	185	11	determination	determination	NOUN
fnp-3025	185	12	of	of	ADP
fnp-3025	185	13	the	the	DET
fnp-3025	185	14	amino	amino	NOUN
fnp-3025	185	15	acid	acid	NOUN
fnp-3025	185	16	sequence	sequence	NOUN
fnp-3025	185	17	of	of	ADP
fnp-3025	185	18	aβ	aβ	NOUN
fnp-3025	185	19	[	[	X
fnp-3025	185	20	2	2	NUM
fnp-3025	185	21	-	-	SYM
fnp-3025	185	22	4	4	NUM
fnp-3025	185	23	]	]	PUNCT
fnp-3025	185	24	prompted	prompt	VERB
fnp-3025	185	25	the	the	DET
fnp-3025	185	26	development	development	NOUN
fnp-3025	185	27	of	of	ADP
fnp-3025	185	28	sensitive	sensitive	ADJ
fnp-3025	185	29	and	and	CCONJ
fnp-3025	185	30	specific	specific	ADJ
fnp-3025	185	31	antibodies	antibody	NOUN
fnp-3025	185	32	that	that	PRON
fnp-3025	185	33	have	have	AUX
fnp-3025	185	34	facilitated	facilitate	VERB
fnp-3025	185	35	the	the	DET
fnp-3025	185	36	investigation	investigation	NOUN
fnp-3025	185	37	of	of	ADP
fnp-3025	185	38	the	the	DET
fnp-3025	185	39	anatomic	anatomic	ADJ
fnp-3025	185	40	localization	localization	NOUN
fnp-3025	185	41	,	,	PUNCT
fnp-3025	185	42	structural	structural	ADJ
fnp-3025	185	43	diversity	diversity	NOUN
fnp-3025	185	44	,	,	PUNCT
fnp-3025	185	45	and	and	CCONJ
fnp-3025	185	46	biochemical	biochemical	ADJ
fnp-3025	185	47	composition	composition	NOUN
fnp-3025	185	48	of	of	ADP
fnp-3025	185	49	aβ	aβ	DET
fnp-3025	185	50	deposits	deposit	NOUN
fnp-3025	185	51	in	in	ADP
fnp-3025	185	52	the	the	DET
fnp-3025	185	53	brain	brain	NOUN
fnp-3025	185	54	.	.	PUNCT
fnp-3025	186	1	aβ	aβ	PRON
fnp-3025	186	2	plaques	plaque	NOUN
fnp-3025	186	3	become	become	VERB
fnp-3025	186	4	increasingly	increasingly	ADV
fnp-3025	186	5	frequent	frequent	ADJ
fnp-3025	186	6	as	as	SCONJ
fnp-3025	186	7	age	age	NOUN
fnp-3025	186	8	advances	advance	NOUN
fnp-3025	186	9	[	[	X
fnp-3025	186	10	80	80	NUM
fnp-3025	186	11	,	,	PUNCT
fnp-3025	186	12	138	138	NUM
fnp-3025	186	13	]	]	PUNCT
fnp-3025	186	14	,	,	PUNCT
fnp-3025	186	15	but	but	CCONJ
fnp-3025	186	16	they	they	PRON
fnp-3025	186	17	are	be	AUX
fnp-3025	186	18	especially	especially	ADV
fnp-3025	186	19	numerous	numerous	ADJ
fnp-3025	186	20	in	in	ADP
fnp-3025	186	21	ad	ad	NOUN
fnp-3025	186	22	patients	patient	NOUN
fnp-3025	186	23	.	.	PUNCT
fnp-3025	187	1	the	the	DET
fnp-3025	187	2	anatomic	anatomic	ADJ
fnp-3025	187	3	distribution	distribution	NOUN
fnp-3025	187	4	of	of	ADP
fnp-3025	187	5	aβ	aβ	DET
fnp-3025	187	6	plaques	plaque	NOUN
fnp-3025	187	7	is	be	AUX
fnp-3025	187	8	variable	variable	ADJ
fnp-3025	187	9	,	,	PUNCT
fnp-3025	187	10	and	and	CCONJ
fnp-3025	187	11	it	it	PRON
fnp-3025	187	12	differs	differ	VERB
fnp-3025	187	13	both	both	PRON
fnp-3025	187	14	among	among	ADP
fnp-3025	187	15	individuals	individual	NOUN
fnp-3025	187	16	and	and	CCONJ
fnp-3025	187	17	among	among	ADP
fnp-3025	187	18	brain	brain	NOUN
fnp-3025	187	19	regions	region	NOUN
fnp-3025	187	20	in	in	ADP
fnp-3025	187	21	a	a	DET
fnp-3025	187	22	given	give	VERB
fnp-3025	187	23	person	person	NOUN
fnp-3025	187	24	[	[	X
fnp-3025	187	25	139	139	NUM
fnp-3025	187	26	-	-	SYM
fnp-3025	187	27	141	141	NUM
fnp-3025	187	28	]	]	PUNCT
fnp-3025	187	29	(	(	PUNCT
fnp-3025	187	30	figure	figure	NOUN
fnp-3025	187	31	5	5	NUM
fnp-3025	187	32	)	)	PUNCT
fnp-3025	187	33	.	.	PUNCT
fnp-3025	188	1	in	in	ADP
fnp-3025	188	2	general	general	ADJ
fnp-3025	188	3	,	,	PUNCT
fnp-3025	188	4	association	association	NOUN
fnp-3025	188	5	areas	area	NOUN
fnp-3025	188	6	of	of	ADP
fnp-3025	188	7	the	the	DET
fnp-3025	188	8	neocortex	neocortex	NOUN
fnp-3025	188	9	are	be	AUX
fnp-3025	188	10	more	more	ADV
fnp-3025	188	11	vulnerable	vulnerable	ADJ
fnp-3025	188	12	and/or	and/or	CCONJ
fnp-3025	188	13	affected	affect	VERB
fnp-3025	188	14	earlier	early	ADV
fnp-3025	188	15	than	than	SCONJ
fnp-3025	188	16	are	be	AUX
fnp-3025	188	17	primary	primary	ADJ
fnp-3025	188	18	motor	motor	NOUN
fnp-3025	188	19	and	and	CCONJ
fnp-3025	188	20	sensory	sensory	ADJ
fnp-3025	188	21	areas	area	NOUN
fnp-3025	188	22	[	[	X
fnp-3025	188	23	140	140	NUM
fnp-3025	188	24	]	]	PUNCT
fnp-3025	188	25	.	.	PUNCT
fnp-3025	189	1	aβ	aβ	PRON
fnp-3025	189	2	deposition	deposition	NOUN
fnp-3025	189	3	is	be	AUX
fnp-3025	189	4	particularly	particularly	ADV
fnp-3025	189	5	profuse	profuse	NOUN
fnp-3025	189	6	in	in	ADP
fnp-3025	189	7	the	the	DET
fnp-3025	189	8	default	default	NOUN
fnp-3025	189	9	mode	mode	NOUN
fnp-3025	189	10	network	network	NOUN
fnp-3025	189	11	,	,	PUNCT
fnp-3025	189	12	an	an	DET
fnp-3025	189	13	interconnected	interconnected	ADJ
fnp-3025	189	14	assemblage	assemblage	NOUN
fnp-3025	189	15	of	of	ADP
fnp-3025	189	16	brain	brain	NOUN
fnp-3025	189	17	regions	region	NOUN
fnp-3025	189	18	that	that	PRON
fnp-3025	189	19	maintain	maintain	VERB
fnp-3025	189	20	vigorous	vigorous	ADJ
fnp-3025	189	21	metabolic	metabolic	NOUN
fnp-3025	189	22	activity	activity	NOUN
fnp-3025	189	23	when	when	SCONJ
fnp-3025	189	24	the	the	DET
fnp-3025	189	25	brain	brain	NOUN
fnp-3025	189	26	is	be	AUX
fnp-3025	189	27	in	in	ADP
fnp-3025	189	28	an	an	DET
fnp-3025	189	29	otherwise	otherwise	ADV
fnp-3025	189	30	resting	rest	VERB
fnp-3025	189	31	state	state	NOUN
fnp-3025	189	32	[	[	X
fnp-3025	189	33	142	142	NUM
fnp-3025	189	34	]	]	PUNCT
fnp-3025	189	35	.	.	PUNCT
fnp-3025	190	1	the	the	DET
fnp-3025	190	2	structure	structure	NOUN
fnp-3025	190	3	of	of	ADP
fnp-3025	190	4	aβ	aβ	DET
fnp-3025	190	5	plaques	plaque	NOUN
fnp-3025	190	6	is	be	AUX
fnp-3025	190	7	influenced	influence	VERB
fnp-3025	190	8	in	in	ADP
fnp-3025	190	9	part	part	NOUN
fnp-3025	190	10	by	by	ADP
fnp-3025	190	11	the	the	DET
fnp-3025	190	12	architectonic	architectonic	ADJ
fnp-3025	190	13	characteristics	characteristic	NOUN
fnp-3025	190	14	of	of	ADP
fnp-3025	190	15	the	the	DET
fnp-3025	190	16	areas	area	NOUN
fnp-3025	190	17	in	in	ADP
fnp-3025	190	18	which	which	PRON
fnp-3025	190	19	they	they	PRON
fnp-3025	190	20	form	form	VERB
fnp-3025	190	21	[	[	X
fnp-3025	190	22	139	139	NUM
fnp-3025	190	23	,	,	PUNCT
fnp-3025	190	24	143	143	NUM
fnp-3025	190	25	]	]	PUNCT
fnp-3025	190	26	,	,	PUNCT
fnp-3025	190	27	but	but	CCONJ
fnp-3025	190	28	it	it	PRON
fnp-3025	190	29	is	be	AUX
fnp-3025	190	30	usual	usual	ADJ
fnp-3025	190	31	for	for	SCONJ
fnp-3025	190	32	several	several	ADJ
fnp-3025	190	33	kinds	kind	NOUN
fnp-3025	190	34	of	of	ADP
fnp-3025	190	35	plaque	plaque	NOUN
fnp-3025	190	36	to	to	PART
fnp-3025	190	37	intermix	intermix	VERB
fnp-3025	190	38	within	within	ADP
fnp-3025	190	39	a	a	DET
fnp-3025	190	40	given	give	VERB
fnp-3025	190	41	site	site	NOUN
fnp-3025	190	42	(	(	PUNCT
fnp-3025	190	43	figure	figure	NOUN
fnp-3025	190	44	6	6	NUM
fnp-3025	190	45	)	)	PUNCT
fnp-3025	190	46	.	.	PUNCT
fnp-3025	191	1	in	in	ADP
fnp-3025	191	2	the	the	DET
fnp-3025	191	3	neocortex	neocortex	NOUN
fnp-3025	191	4	,	,	PUNCT
fnp-3025	191	5	the	the	DET
fnp-3025	191	6	laminar	laminar	ADJ
fnp-3025	191	7	distribution	distribution	NOUN
fnp-3025	191	8	of	of	ADP
fnp-3025	191	9	diverse	diverse	ADJ
fnp-3025	191	10	aβ	aβ	PRON
fnp-3025	191	11	plaques	plaque	NOUN
fnp-3025	191	12	can	can	AUX
fnp-3025	191	13	vary	vary	VERB
fnp-3025	191	14	markedly	markedly	ADV
fnp-3025	191	15	[	[	X
fnp-3025	191	16	140	140	NUM
fnp-3025	191	17	]	]	PUNCT
fnp-3025	191	18	(	(	PUNCT
fnp-3025	191	19	figure	figure	NOUN
fnp-3025	191	20	5	5	NUM
fnp-3025	191	21	)	)	PUNCT
fnp-3025	191	22	.	.	PUNCT
fnp-3025	192	1	figure	figure	NOUN
fnp-3025	192	2	5	5	NUM
fnp-3025	192	3	.	.	PUNCT
fnp-3025	192	4	variation	variation	NOUN
fnp-3025	192	5	in	in	ADP
fnp-3025	192	6	aβ	aβ	ADJ
fnp-3025	192	7	deposition	deposition	NOUN
fnp-3025	192	8	in	in	ADP
fnp-3025	192	9	adjacent	adjacent	ADJ
fnp-3025	192	10	cortical	cortical	ADJ
fnp-3025	192	11	gyri	gyri	NOUN
fnp-3025	192	12	from	from	ADP
fnp-3025	192	13	an	an	DET
fnp-3025	192	14	ad	ad	NOUN
fnp-3025	192	15	patient	patient	NOUN
fnp-3025	192	16	.	.	PUNCT
fnp-3025	193	1	antibody	antibody	NOUN
fnp-3025	193	2	4g8	4g8	NUM
fnp-3025	193	3	,	,	PUNCT
fnp-3025	193	4	nissl	nissl	ADJ
fnp-3025	193	5	counterstain	counterstain	NOUN
fnp-3025	193	6	.	.	PUNCT
fnp-3025	194	1	bar	bar	NOUN
fnp-3025	194	2	=	=	SYM
fnp-3025	194	3	500μm	500μm	NOUN
fnp-3025	194	4	.	.	PUNCT
fnp-3025	195	1	figure	figure	VERB
fnp-3025	195	2	6	6	NUM
fnp-3025	195	3	.	.	PUNCT
fnp-3025	195	4	variable	variable	ADJ
fnp-3025	195	5	morphology	morphology	NOUN
fnp-3025	195	6	of	of	ADP
fnp-3025	195	7	aβ	aβ	DET
fnp-3025	195	8	plaques	plaque	NOUN
fnp-3025	195	9	in	in	ADP
fnp-3025	195	10	the	the	DET
fnp-3025	195	11	cortex	cortex	NOUN
fnp-3025	195	12	of	of	ADP
fnp-3025	195	13	an	an	DET
fnp-3025	195	14	ad	ad	NOUN
fnp-3025	195	15	patient	patient	NOUN
fnp-3025	195	16	.	.	PUNCT
fnp-3025	196	1	classical	classical	ADJ
fnp-3025	196	2	dense	dense	ADV
fnp-3025	196	3	-	-	PUNCT
fnp-3025	196	4	cored	core	VERB
fnp-3025	196	5	plaques	plaque	NOUN
fnp-3025	196	6	with	with	ADP
fnp-3025	196	7	the	the	DET
fnp-3025	196	8	core	core	NOUN
fnp-3025	196	9	-	-	PUNCT
fnp-3025	196	10	space	space	NOUN
fnp-3025	196	11	-	-	PUNCT
fnp-3025	196	12	corona	corona	NOUN
fnp-3025	196	13	pattern	pattern	NOUN
fnp-3025	196	14	are	be	AUX
fnp-3025	196	15	in	in	ADP
fnp-3025	196	16	the	the	DET
fnp-3025	196	17	upper	upper	ADJ
fnp-3025	196	18	left	left	NOUN
fnp-3025	196	19	and	and	CCONJ
fnp-3025	196	20	lower	low	ADJ
fnp-3025	196	21	right	right	ADJ
fnp-3025	196	22	,	,	PUNCT
fnp-3025	196	23	and	and	CCONJ
fnp-3025	196	24	an	an	DET
fnp-3025	196	25	irregular	irregular	ADJ
fnp-3025	196	26	cloud	cloud	NOUN
fnp-3025	196	27	of	of	ADP
fnp-3025	196	28	diffuse	diffuse	PROPN
fnp-3025	196	29	material	material	NOUN
fnp-3025	196	30	is	be	AUX
fnp-3025	196	31	near	near	ADP
fnp-3025	196	32	the	the	DET
fnp-3025	196	33	center	center	NOUN
fnp-3025	196	34	,	,	PUNCT
fnp-3025	196	35	along	along	ADP
fnp-3025	196	36	with	with	ADP
fnp-3025	196	37	numerous	numerous	ADJ
fnp-3025	196	38	very	very	ADV
fnp-3025	196	39	small	small	ADJ
fnp-3025	196	40	patches	patch	NOUN
fnp-3025	196	41	.	.	PUNCT
fnp-3025	197	1	antibody	antibody	NOUN
fnp-3025	197	2	4g8	4g8	NUM
fnp-3025	197	3	;	;	PUNCT
fnp-3025	197	4	nissl	nissl	ADJ
fnp-3025	197	5	counterstain	counterstain	NOUN
fnp-3025	197	6	.	.	PUNCT
fnp-3025	198	1	bar	bar	NOUN
fnp-3025	198	2	=	=	SYM
fnp-3025	198	3	50μm	50μm	NOUN
fnp-3025	198	4	.	.	PUNCT
fnp-3025	199	1	based	base	VERB
fnp-3025	199	2	on	on	ADP
fnp-3025	199	3	an	an	DET
fnp-3025	199	4	analysis	analysis	NOUN
fnp-3025	199	5	of	of	ADP
fnp-3025	199	6	human	human	ADJ
fnp-3025	199	7	brains	brain	NOUN
fnp-3025	199	8	with	with	ADP
fnp-3025	199	9	different	different	ADJ
fnp-3025	199	10	degrees	degree	NOUN
fnp-3025	199	11	of	of	ADP
fnp-3025	199	12	plaque	plaque	NOUN
fnp-3025	199	13	accumulation	accumulation	NOUN
fnp-3025	199	14	,	,	PUNCT
fnp-3025	199	15	a	a	DET
fnp-3025	199	16	spatiotemporal	spatiotemporal	ADJ
fnp-3025	199	17	course	course	NOUN
fnp-3025	199	18	of	of	ADP
fnp-3025	199	19	aβ	aβ	DET
fnp-3025	199	20	plaque	plaque	NOUN
fnp-3025	199	21	formation	formation	NOUN
fnp-3025	199	22	has	have	AUX
fnp-3025	199	23	been	be	AUX
fnp-3025	199	24	proposed	propose	VERB
fnp-3025	199	25	[	[	X
fnp-3025	199	26	19	19	NUM
fnp-3025	199	27	,	,	PUNCT
fnp-3025	199	28	144	144	NUM
fnp-3025	199	29	,	,	PUNCT
fnp-3025	199	30	145	145	NUM
fnp-3025	199	31	]	]	PUNCT
fnp-3025	199	32	.	.	PUNCT
fnp-3025	200	1	there	there	PRON
fnp-3025	200	2	is	be	VERB
fnp-3025	200	3	general	general	ADJ
fnp-3025	200	4	agreement	agreement	NOUN
fnp-3025	200	5	that	that	PRON
fnp-3025	200	6	diffuse	diffuse	VERB
fnp-3025	200	7	plaques	plaque	NOUN
fnp-3025	200	8	are	be	AUX
fnp-3025	200	9	the	the	DET
fnp-3025	200	10	earliest	early	ADJ
fnp-3025	200	11	type	type	NOUN
fnp-3025	200	12	to	to	PART
fnp-3025	200	13	emerge	emerge	VERB
fnp-3025	200	14	,	,	PUNCT
fnp-3025	200	15	followed	follow	VERB
fnp-3025	200	16	later	later	ADV
fnp-3025	200	17	by	by	ADP
fnp-3025	200	18	cored	cored	PROPN
fnp-3025	200	19	(	(	PUNCT
fnp-3025	200	20	amyloid	amyloid	NOUN
fnp-3025	200	21	)	)	PUNCT
fnp-3025	200	22	plaques	plaque	NOUN
fnp-3025	200	23	[	[	X
fnp-3025	200	24	146	146	NUM
fnp-3025	200	25	]	]	PUNCT
fnp-3025	200	26	.	.	PUNCT
fnp-3025	201	1	according	accord	VERB
fnp-3025	201	2	to	to	ADP
fnp-3025	201	3	thal	thal	NOUN
fnp-3025	201	4	and	and	CCONJ
fnp-3025	201	5	colleagues	colleague	NOUN
fnp-3025	201	6	,	,	PUNCT
fnp-3025	201	7	in	in	ADP
fnp-3025	201	8	the	the	DET
fnp-3025	201	9	first	first	ADJ
fnp-3025	201	10	phase	phase	NOUN
fnp-3025	201	11	of	of	ADP
fnp-3025	201	12	the	the	DET
fnp-3025	201	13	process	process	NOUN
fnp-3025	201	14	,	,	PUNCT
fnp-3025	201	15	diffuse	diffuse	VERB
fnp-3025	201	16	aβ	aβ	ADP
fnp-3025	201	17	plaques	plaque	NOUN
fnp-3025	201	18	appear	appear	VERB
fnp-3025	201	19	in	in	ADP
fnp-3025	201	20	the	the	DET
fnp-3025	201	21	neo(iso)cortex	neo(iso)cortex	NOUN
fnp-3025	201	22	;	;	PUNCT
fnp-3025	201	23	in	in	ADP
fnp-3025	201	24	the	the	DET
fnp-3025	201	25	second	second	ADJ
fnp-3025	201	26	phase	phase	NOUN
fnp-3025	201	27	,	,	PUNCT
fnp-3025	201	28	allocortex	allocortex	NOUN
fnp-3025	201	29	,	,	PUNCT
fnp-3025	201	30	the	the	DET
fnp-3025	201	31	hippocampal	hippocampal	ADJ
fnp-3025	201	32	formation	formation	NOUN
fnp-3025	201	33	and	and	CCONJ
fnp-3025	201	34	amygdala	amygdala	NOUN
fnp-3025	201	35	are	be	AUX
fnp-3025	201	36	affected	affect	VERB
fnp-3025	201	37	;	;	PUNCT
fnp-3025	201	38	in	in	ADP
fnp-3025	201	39	the	the	DET
fnp-3025	201	40	third	third	ADJ
fnp-3025	201	41	phase	phase	NOUN
fnp-3025	201	42	,	,	PUNCT
fnp-3025	201	43	plaques	plaque	NOUN
fnp-3025	201	44	arise	arise	VERB
fnp-3025	201	45	in	in	ADP
fnp-3025	201	46	the	the	DET
fnp-3025	201	47	basal	basal	ADJ
fnp-3025	201	48	ganglia	ganglia	NOUN
fnp-3025	201	49	and	and	CCONJ
fnp-3025	201	50	diencephalon	diencephalon	NOUN
fnp-3025	201	51	;	;	PUNCT
fnp-3025	201	52	in	in	ADP
fnp-3025	201	53	the	the	DET
fnp-3025	201	54	fourth	fourth	ADJ
fnp-3025	201	55	phase	phase	NOUN
fnp-3025	201	56	they	they	PRON
fnp-3025	201	57	appear	appear	VERB
fnp-3025	201	58	in	in	ADP
fnp-3025	201	59	the	the	DET
fnp-3025	201	60	midbrain	midbrain	NOUN
fnp-3025	201	61	and	and	CCONJ
fnp-3025	201	62	medulla	medulla	NOUN
fnp-3025	201	63	oblongata	oblongata	NOUN
fnp-3025	201	64	;	;	PUNCT
fnp-3025	201	65	and	and	CCONJ
fnp-3025	201	66	in	in	ADP
fnp-3025	201	67	the	the	DET
fnp-3025	201	68	fifth	fifth	ADJ
fnp-3025	201	69	phase	phase	NOUN
fnp-3025	201	70	,	,	PUNCT
fnp-3025	201	71	the	the	DET
fnp-3025	201	72	pons	pon	NOUN
fnp-3025	201	73	and	and	CCONJ
fnp-3025	201	74	cerebellum	cerebellum	NOUN
fnp-3025	201	75	are	be	AUX
fnp-3025	201	76	affected	affect	VERB
fnp-3025	201	77	[	[	X
fnp-3025	201	78	19	19	NUM
fnp-3025	201	79	,	,	PUNCT
fnp-3025	201	80	144	144	NUM
fnp-3025	201	81	,	,	PUNCT
fnp-3025	201	82	145	145	NUM
fnp-3025	201	83	]	]	PUNCT
fnp-3025	201	84	(	(	PUNCT
fnp-3025	201	85	figure	figure	NOUN
fnp-3025	201	86	7	7	NUM
fnp-3025	201	87	)	)	PUNCT
fnp-3025	201	88	.	.	PUNCT
fnp-3025	202	1	these	these	DET
fnp-3025	202	2	stages	stage	NOUN
fnp-3025	202	3	have	have	AUX
fnp-3025	202	4	been	be	AUX
fnp-3025	202	5	consolidated	consolidate	VERB
fnp-3025	202	6	by	by	ADP
fnp-3025	202	7	serrano	serrano	PROPN
fnp-3025	202	8	-	-	PUNCT
fnp-3025	202	9	pozo	pozo	PROPN
fnp-3025	202	10	and	and	CCONJ
fnp-3025	202	11	colleagues	colleague	NOUN
fnp-3025	202	12	[	[	X
fnp-3025	202	13	133	133	NUM
fnp-3025	202	14	]	]	PUNCT
fnp-3025	202	15	into	into	ADP
fnp-3025	202	16	an	an	DET
fnp-3025	202	17	isocortical	isocortical	ADJ
fnp-3025	202	18	stage	stage	NOUN
fnp-3025	202	19	1	1	NUM
fnp-3025	202	20	,	,	PUNCT
fnp-3025	202	21	allocortical	allocortical	ADJ
fnp-3025	202	22	/	/	SYM
fnp-3025	202	23	limbic	limbic	ADJ
fnp-3025	202	24	stage	stage	NOUN
fnp-3025	202	25	2	2	NUM
fnp-3025	202	26	,	,	PUNCT
fnp-3025	202	27	and	and	CCONJ
fnp-3025	202	28	subcortical	subcortical	ADJ
fnp-3025	202	29	stage	stage	NOUN
fnp-3025	202	30	3	3	NUM
fnp-3025	202	31	.	.	PUNCT
fnp-3025	203	1	this	this	DET
fnp-3025	203	2	general	general	ADJ
fnp-3025	203	3	pattern	pattern	NOUN
fnp-3025	203	4	of	of	ADP
fnp-3025	203	5	spread	spread	NOUN
fnp-3025	203	6	has	have	AUX
fnp-3025	203	7	been	be	AUX
fnp-3025	203	8	confirmed	confirm	VERB
fnp-3025	203	9	by	by	ADP
fnp-3025	203	10	a	a	DET
fnp-3025	203	11	cross	cross	ADJ
fnp-3025	203	12	-	-	ADJ
fnp-3025	203	13	sectional	sectional	ADJ
fnp-3025	203	14	in	in	ADP
fnp-3025	203	15	vivo	vivo	ADJ
fnp-3025	203	16	analysis	analysis	NOUN
fnp-3025	203	17	of	of	ADP
fnp-3025	203	18	aβ	aβ	NOUN
fnp-3025	203	19	-	-	PUNCT
fnp-3025	203	20	amyloid	amyloid	NOUN
fnp-3025	203	21	deposition	deposition	NOUN
fnp-3025	203	22	profiles	profile	NOUN
fnp-3025	203	23	using	use	VERB
fnp-3025	203	24	florbetapir	florbetapir	NOUN
fnp-3025	203	25	-	-	PUNCT
fnp-3025	203	26	pet	pet	NOUN
fnp-3025	203	27	imaging	imaging	NOUN
fnp-3025	203	28	[	[	X
fnp-3025	203	29	147	147	NUM
fnp-3025	203	30	]	]	PUNCT
fnp-3025	203	31	.	.	PUNCT
fnp-3025	204	1	thus	thus	ADV
fnp-3025	204	2	,	,	PUNCT
fnp-3025	204	3	in	in	ADP
fnp-3025	204	4	the	the	DET
fnp-3025	204	5	end	end	NOUN
fnp-3025	204	6	-	-	PUNCT
fnp-3025	204	7	stage	stage	NOUN
fnp-3025	204	8	of	of	ADP
fnp-3025	204	9	ad	ad	NOUN
fnp-3025	204	10	,	,	PUNCT
fnp-3025	204	11	most	most	ADJ
fnp-3025	204	12	brain	brain	NOUN
fnp-3025	204	13	areas	area	NOUN
fnp-3025	204	14	exhibit	exhibit	VERB
fnp-3025	204	15	at	at	ADP
fnp-3025	204	16	least	least	ADJ
fnp-3025	204	17	some	some	PRON
fnp-3025	204	18	aβ	aβ	NOUN
fnp-3025	204	19	deposition	deposition	NOUN
fnp-3025	204	20	.	.	PUNCT
fnp-3025	205	1	the	the	DET
fnp-3025	205	2	spinal	spinal	ADJ
fnp-3025	205	3	cord	cord	NOUN
fnp-3025	205	4	has	have	AUX
fnp-3025	205	5	been	be	AUX
fnp-3025	205	6	less	less	ADV
fnp-3025	205	7	studied	study	VERB
fnp-3025	205	8	;	;	PUNCT
fnp-3025	205	9	while	while	SCONJ
fnp-3025	205	10	it	it	PRON
fnp-3025	205	11	appears	appear	VERB
fnp-3025	205	12	to	to	PART
fnp-3025	205	13	be	be	AUX
fnp-3025	205	14	largely	largely	ADV
fnp-3025	205	15	spared	spare	VERB
fnp-3025	205	16	,	,	PUNCT
fnp-3025	205	17	plaques	plaque	NOUN
fnp-3025	205	18	there	there	ADV
fnp-3025	205	19	have	have	AUX
fnp-3025	205	20	been	be	AUX
fnp-3025	205	21	reported	report	VERB
fnp-3025	205	22	in	in	ADP
fnp-3025	205	23	some	some	DET
fnp-3025	205	24	instances	instance	NOUN
fnp-3025	205	25	[	[	X
fnp-3025	205	26	93	93	NUM
fnp-3025	205	27	,	,	PUNCT
fnp-3025	205	28	148	148	NUM
fnp-3025	205	29	]	]	PUNCT
fnp-3025	205	30	.	.	PUNCT
fnp-3025	206	1	figure	figure	NOUN
fnp-3025	206	2	7	7	NUM
fnp-3025	206	3	.	.	PUNCT
fnp-3025	207	1	the	the	DET
fnp-3025	207	2	phases	phase	NOUN
fnp-3025	207	3	of	of	ADP
fnp-3025	207	4	aβ	aβ	NOUN
fnp-3025	207	5	plaque	plaque	NOUN
fnp-3025	207	6	distribution	distribution	NOUN
fnp-3025	207	7	in	in	ADP
fnp-3025	207	8	the	the	DET
fnp-3025	207	9	brain	brain	NOUN
fnp-3025	208	1	[	[	X
fnp-3025	208	2	references	reference	NOUN
fnp-3025	208	3	19	19	NUM
fnp-3025	208	4	,	,	PUNCT
fnp-3025	208	5	145	145	NUM
fnp-3025	208	6	]	]	PUNCT
fnp-3025	208	7	;	;	PUNCT
fnp-3025	208	8	illustration	illustration	NOUN
fnp-3025	208	9	courtesy	courtesy	NOUN
fnp-3025	208	10	of	of	ADP
fnp-3025	208	11	dietmar	dietmar	PROPN
fnp-3025	208	12	thal	thal	PROPN
fnp-3025	208	13	,	,	PUNCT
fnp-3025	208	14	ku	ku	PROPN
fnp-3025	208	15	leuven	leuven	PROPN
fnp-3025	208	16	.	.	PUNCT
fnp-3025	209	1	4.2	4.2	NUM
fnp-3025	209	2	.	.	PUNCT
fnp-3025	210	1	in	in	ADP
fnp-3025	210	2	vivo	vivo	ADJ
fnp-3025	210	3	imaging	imaging	NOUN
fnp-3025	210	4	at	at	ADP
fnp-3025	210	5	the	the	DET
fnp-3025	210	6	turn	turn	NOUN
fnp-3025	210	7	of	of	ADP
fnp-3025	210	8	the	the	DET
fnp-3025	210	9	21st	21st	ADJ
fnp-3025	210	10	century	century	NOUN
fnp-3025	210	11	,	,	PUNCT
fnp-3025	210	12	the	the	DET
fnp-3025	210	13	first	first	ADJ
fnp-3025	210	14	imaging	imaging	ADJ
fnp-3025	210	15	agents	agent	NOUN
fnp-3025	210	16	were	be	AUX
fnp-3025	210	17	introduced	introduce	VERB
fnp-3025	210	18	to	to	PART
fnp-3025	210	19	detect	detect	VERB
fnp-3025	210	20	amyloid	amyloid	NOUN
fnp-3025	210	21	in	in	ADP
fnp-3025	210	22	the	the	DET
fnp-3025	210	23	living	live	VERB
fnp-3025	210	24	human	human	ADJ
fnp-3025	210	25	brain	brain	NOUN
fnp-3025	210	26	via	via	ADP
fnp-3025	210	27	positron	positron	NOUN
fnp-3025	210	28	emission	emission	NOUN
fnp-3025	210	29	tomography	tomography	NOUN
fnp-3025	210	30	[	[	X
fnp-3025	210	31	149	149	NUM
fnp-3025	210	32	,	,	PUNCT
fnp-3025	210	33	150	150	NUM
fnp-3025	210	34	]	]	PUNCT
fnp-3025	210	35	.	.	PUNCT
fnp-3025	211	1	jorge	jorge	PROPN
fnp-3025	211	2	barrio	barrio	PROPN
fnp-3025	211	3	and	and	CCONJ
fnp-3025	211	4	colleagues	colleague	NOUN
fnp-3025	211	5	introduced	introduce	VERB
fnp-3025	211	6	2-(1-[[6-[(2-[18f]fluoroethyl)(methyl)amino]-2	2-(1-[[6-[(2-[18f]fluoroethyl)(methyl)amino]-2	PROPN
fnp-3025	211	7	-	-	PUNCT
fnp-3025	211	8	naphthyl]]ethylidene	naphthyl]]ethylidene	NUM
fnp-3025	211	9	)	)	PUNCT
fnp-3025	211	10	malononitrile	malononitrile	NOUN
fnp-3025	211	11	(	(	PUNCT
fnp-3025	211	12	[	[	X
fnp-3025	211	13	18f]fddnp	18f]fddnp	NUM
fnp-3025	211	14	)	)	PUNCT
fnp-3025	211	15	,	,	PUNCT
fnp-3025	211	16	which	which	PRON
fnp-3025	211	17	binds	bind	VERB
fnp-3025	211	18	to	to	ADP
fnp-3025	211	19	both	both	PRON
fnp-3025	211	20	aβ	aβ	NOUN
fnp-3025	211	21	-	-	PUNCT
fnp-3025	211	22	amyloid	amyloid	NOUN
fnp-3025	211	23	and	and	CCONJ
fnp-3025	211	24	tau	tau	PROPN
fnp-3025	211	25	tangles	tangle	NOUN
fnp-3025	211	26	,	,	PUNCT
fnp-3025	211	27	and	and	CCONJ
fnp-3025	211	28	which	which	PRON
fnp-3025	211	29	has	have	AUX
fnp-3025	211	30	achieved	achieve	VERB
fnp-3025	211	31	some	some	DET
fnp-3025	211	32	utility	utility	NOUN
fnp-3025	211	33	in	in	ADP
fnp-3025	211	34	diagnosing	diagnose	VERB
fnp-3025	211	35	tauopathies	tauopathie	NOUN
fnp-3025	212	1	[	[	X
fnp-3025	212	2	151	151	NUM
fnp-3025	212	3	-	-	SYM
fnp-3025	212	4	153	153	NUM
fnp-3025	212	5	]	]	PUNCT
fnp-3025	212	6	.	.	PUNCT
fnp-3025	213	1	a	a	DET
fnp-3025	213	2	more	more	ADV
fnp-3025	213	3	aβ	aβ	NOUN
fnp-3025	213	4	-	-	PUNCT
fnp-3025	213	5	selective	selective	ADJ
fnp-3025	213	6	ligand	ligand	NOUN
fnp-3025	213	7	,	,	PUNCT
fnp-3025	213	8	developed	develop	VERB
fnp-3025	213	9	by	by	ADP
fnp-3025	213	10	william	william	PROPN
fnp-3025	213	11	klunk	klunk	PROPN
fnp-3025	213	12	,	,	PUNCT
fnp-3025	213	13	chester	chester	PROPN
fnp-3025	213	14	mathis	mathis	PROPN
fnp-3025	213	15	and	and	CCONJ
fnp-3025	213	16	colleagues	colleague	NOUN
fnp-3025	213	17	,	,	PUNCT
fnp-3025	213	18	is	be	AUX
fnp-3025	213	19	2-(4’-[11c]methylamino	2-(4’-[11c]methylamino	NUM
fnp-3025	213	20	-	-	PUNCT
fnp-3025	213	21	phenyl)-6	phenyl)-6	NOUN
fnp-3025	213	22	-	-	PUNCT
fnp-3025	213	23	hydroxybenzothiazole	hydroxybenzothiazole	NOUN
fnp-3025	213	24	(	(	PUNCT
fnp-3025	213	25	pittsburgh	pittsburgh	PROPN
fnp-3025	213	26	compound	compound	PROPN
fnp-3025	213	27	-	-	PUNCT
fnp-3025	213	28	b	b	NOUN
fnp-3025	214	1	[	[	X
fnp-3025	214	2	pib	pib	NOUN
fnp-3025	214	3	]	]	X
fnp-3025	214	4	)	)	PUNCT
fnp-3025	215	1	[	[	X
fnp-3025	215	2	149	149	NUM
fnp-3025	215	3	,	,	PUNCT
fnp-3025	215	4	154	154	NUM
fnp-3025	215	5	]	]	PUNCT
fnp-3025	215	6	.	.	PUNCT
fnp-3025	216	1	derived	derive	VERB
fnp-3025	216	2	from	from	ADP
fnp-3025	216	3	the	the	DET
fnp-3025	216	4	chemical	chemical	NOUN
fnp-3025	216	5	structure	structure	NOUN
fnp-3025	216	6	of	of	ADP
fnp-3025	216	7	the	the	DET
fnp-3025	216	8	histologic	histologic	NOUN
fnp-3025	216	9	staining	stain	VERB
fnp-3025	216	10	agent	agent	NOUN
fnp-3025	216	11	thioflavin	thioflavin	PROPN
fnp-3025	216	12	-	-	PUNCT
fnp-3025	216	13	t	t	PROPN
fnp-3025	216	14	,	,	PUNCT
fnp-3025	216	15	pib	pib	PROPN
fnp-3025	216	16	crosses	cross	VERB
fnp-3025	216	17	the	the	DET
fnp-3025	216	18	blood	blood	NOUN
fnp-3025	216	19	-	-	PUNCT
fnp-3025	216	20	brain	brain	NOUN
fnp-3025	216	21	barrier	barrier	NOUN
fnp-3025	216	22	and	and	CCONJ
fnp-3025	216	23	binds	bind	VERB
fnp-3025	216	24	with	with	ADP
fnp-3025	216	25	high	high	ADJ
fnp-3025	216	26	affinity	affinity	NOUN
fnp-3025	216	27	and	and	CCONJ
fnp-3025	216	28	selectivity	selectivity	NOUN
fnp-3025	216	29	to	to	ADP
fnp-3025	216	30	aβ	aβ	NOUN
fnp-3025	216	31	deposits	deposit	NOUN
fnp-3025	216	32	in	in	ADP
fnp-3025	216	33	plaques	plaque	NOUN
fnp-3025	216	34	and	and	CCONJ
fnp-3025	216	35	caa	caa	VERB
fnp-3025	217	1	[	[	X
fnp-3025	217	2	154].9	154].9	NUM
fnp-3025	217	3	pib	pib	NOUN
fnp-3025	217	4	(	(	PUNCT
fnp-3025	217	5	which	which	PRON
fnp-3025	217	6	is	be	AUX
fnp-3025	217	7	labeled	label	VERB
fnp-3025	217	8	with	with	ADP
fnp-3025	217	9	carbon-11	carbon-11	PROPN
fnp-3025	217	10	)	)	PUNCT
fnp-3025	217	11	,	,	PUNCT
fnp-3025	217	12	was	be	AUX
fnp-3025	217	13	followed	follow	VERB
fnp-3025	217	14	by	by	ADP
fnp-3025	217	15	similar	similar	ADJ
fnp-3025	217	16	pet	pet	ADJ
fnp-3025	217	17	ligands	ligand	NOUN
fnp-3025	217	18	labeled	label	VERB
fnp-3025	217	19	with	with	ADP
fnp-3025	217	20	fluorine-18	fluorine-18	PROPN
fnp-3025	217	21	(	(	PUNCT
fnp-3025	217	22	a	a	DET
fnp-3025	217	23	radiolabel	radiolabel	NOUN
fnp-3025	217	24	with	with	ADP
fnp-3025	217	25	a	a	DET
fnp-3025	217	26	longer	long	ADJ
fnp-3025	217	27	half	half	ADJ
fnp-3025	217	28	-	-	PUNCT
fnp-3025	217	29	life	life	NOUN
fnp-3025	217	30	than	than	ADP
fnp-3025	217	31	carbon-11	carbon-11	PROPN
fnp-3025	217	32	):	):	PUNCT
fnp-3025	217	33	florbetapir	florbetapir	NOUN
fnp-3025	217	34	(	(	PUNCT
fnp-3025	217	35	amy	amy	NOUN
fnp-3025	217	36	-	-	PUNCT
fnp-3025	217	37	vid	vid	NOUN
fnp-3025	217	38	)	)	PUNCT
fnp-3025	218	1	[	[	X
fnp-3025	218	2	155	155	NUM
fnp-3025	218	3	,	,	PUNCT
fnp-3025	218	4	156	156	NUM
fnp-3025	218	5	]	]	PUNCT
fnp-3025	218	6	,	,	PUNCT
fnp-3025	218	7	florbetaben	florbetaben	PROPN
fnp-3025	218	8	(	(	PUNCT
fnp-3025	218	9	neuraceq	neuraceq	PROPN
fnp-3025	218	10	)	)	PUNCT
fnp-3025	219	1	[	[	X
fnp-3025	219	2	157	157	NUM
fnp-3025	219	3	]	]	PUNCT
fnp-3025	219	4	,	,	PUNCT
fnp-3025	219	5	and	and	CCONJ
fnp-3025	219	6	flutemetamol	flutemetamol	PROPN
fnp-3025	219	7	(	(	PUNCT
fnp-3025	219	8	vizamyl	vizamyl	NOUN
fnp-3025	219	9	)	)	PUNCT
fnp-3025	220	1	[	[	X
fnp-3025	220	2	158	158	NUM
fnp-3025	220	3	]	]	PUNCT
fnp-3025	220	4	.	.	PUNCT
fnp-3025	221	1	by	by	ADP
fnp-3025	221	2	assessing	assess	VERB
fnp-3025	221	3	aβ	aβ	NOUN
fnp-3025	221	4	-	-	PUNCT
fnp-3025	221	5	amyloid	amyloid	NOUN
fnp-3025	221	6	load	load	NOUN
fnp-3025	221	7	in	in	ADP
fnp-3025	221	8	living	living	NOUN
fnp-3025	221	9	subjects	subject	NOUN
fnp-3025	221	10	,	,	PUNCT
fnp-3025	221	11	these	these	DET
fnp-3025	221	12	imaging	imaging	NOUN
fnp-3025	221	13	agents	agent	NOUN
fnp-3025	221	14	have	have	AUX
fnp-3025	221	15	facilitated	facilitate	VERB
fnp-3025	221	16	the	the	DET
fnp-3025	221	17	differential	differential	ADJ
fnp-3025	221	18	diagnosis	diagnosis	NOUN
fnp-3025	221	19	of	of	ADP
fnp-3025	221	20	ad	ad	NOUN
fnp-3025	221	21	and	and	CCONJ
fnp-3025	221	22	the	the	DET
fnp-3025	221	23	longitudinal	longitudinal	ADJ
fnp-3025	221	24	tracking	tracking	NOUN
fnp-3025	221	25	of	of	ADP
fnp-3025	221	26	aβ	aβ	PRON
fnp-3025	221	27	accumulation	accumulation	NOUN
fnp-3025	221	28	.	.	PUNCT
fnp-3025	222	1	they	they	PRON
fnp-3025	222	2	are	be	AUX
fnp-3025	222	3	particularly	particularly	ADV
fnp-3025	222	4	sensitive	sensitive	ADJ
fnp-3025	222	5	in	in	ADP
fnp-3025	222	6	detecting	detect	VERB
fnp-3025	222	7	dense	dense	ADJ
fnp-3025	222	8	-	-	PUNCT
fnp-3025	222	9	core	core	NOUN
fnp-3025	222	10	aβ	aβ	NOUN
fnp-3025	222	11	plaques	plaque	NOUN
fnp-3025	222	12	,	,	PUNCT
fnp-3025	222	13	although	although	SCONJ
fnp-3025	222	14	they	they	PRON
fnp-3025	222	15	also	also	ADV
fnp-3025	222	16	bind	bind	VERB
fnp-3025	222	17	to	to	ADP
fnp-3025	222	18	some	some	DET
fnp-3025	222	19	extent	extent	NOUN
fnp-3025	222	20	to	to	ADP
fnp-3025	222	21	aβ	aβ	NOUN
fnp-3025	222	22	-	-	PUNCT
fnp-3025	222	23	caa	caa	NOUN
fnp-3025	222	24	and	and	CCONJ
fnp-3025	222	25	diffuse	diffuse	VERB
fnp-3025	222	26	aβ	aβ	NOUN
fnp-3025	222	27	deposits	deposit	NOUN
fnp-3025	223	1	[	[	X
fnp-3025	223	2	47	47	NUM
fnp-3025	223	3	,	,	PUNCT
fnp-3025	223	4	159	159	NUM
fnp-3025	223	5	-	-	SYM
fnp-3025	223	6	161	161	NUM
fnp-3025	223	7	]	]	PUNCT
fnp-3025	223	8	.	.	PUNCT
fnp-3025	224	1	histochemical	histochemical	ADJ
fnp-3025	224	2	analysis	analysis	NOUN
fnp-3025	224	3	of	of	ADP
fnp-3025	224	4	fluorescently	fluorescently	ADV
fnp-3025	224	5	labeled	label	VERB
fnp-3025	224	6	(	(	PUNCT
fnp-3025	224	7	‘	'	PUNCT
fnp-3025	224	8	clicked	click	VERB
fnp-3025	224	9	’	'	PUNCT
fnp-3025	224	10	)	)	PUNCT
fnp-3025	224	11	pib	pib	NOUN
fnp-3025	224	12	applied	apply	VERB
fnp-3025	224	13	to	to	ADP
fnp-3025	224	14	ad	ad	NOUN
fnp-3025	224	15	tissue	tissue	NOUN
fnp-3025	224	16	sections	section	NOUN
fnp-3025	224	17	confirms	confirm	VERB
fnp-3025	224	18	the	the	DET
fnp-3025	224	19	preference	preference	NOUN
fnp-3025	224	20	of	of	ADP
fnp-3025	224	21	pib	pib	NOUN
fnp-3025	224	22	at	at	ADP
fnp-3025	224	23	low	low	ADJ
fnp-3025	224	24	concentration	concentration	NOUN
fnp-3025	224	25	(	(	PUNCT
fnp-3025	224	26	100	100	NUM
fnp-3025	224	27	nm	nm	NOUN
fnp-3025	224	28	)	)	PUNCT
fnp-3025	224	29	for	for	ADP
fnp-3025	224	30	dense	dense	ADJ
fnp-3025	224	31	-	-	PUNCT
fnp-3025	224	32	core	core	NOUN
fnp-3025	224	33	plaques	plaque	NOUN
fnp-3025	225	1	[	[	X
fnp-3025	225	2	162	162	NUM
fnp-3025	225	3	]	]	PUNCT
fnp-3025	225	4	.	.	PUNCT
fnp-3025	226	1	interestingly	interestingly	ADV
fnp-3025	226	2	,	,	PUNCT
fnp-3025	226	3	pib	pib	PROPN
fnp-3025	226	4	does	do	AUX
fnp-3025	226	5	not	not	PART
fnp-3025	226	6	show	show	VERB
fnp-3025	226	7	significant	significant	ADJ
fnp-3025	226	8	high	high	ADJ
fnp-3025	226	9	-	-	PUNCT
fnp-3025	226	10	affinity	affinity	NOUN
fnp-3025	226	11	binding	bind	VERB
fnp-3025	226	12	to	to	ADP
fnp-3025	226	13	aβ	aβ	NOUN
fnp-3025	226	14	-	-	PUNCT
fnp-3025	226	15	amyloid	amyloid	NOUN
fnp-3025	226	16	deposits	deposit	NOUN
fnp-3025	226	17	in	in	ADP
fnp-3025	226	18	aged	aged	ADJ
fnp-3025	226	19	nonhuman	nonhuman	ADJ
fnp-3025	226	20	primates	primate	NOUN
fnp-3025	226	21	with	with	ADP
fnp-3025	226	22	substantial	substantial	ADJ
fnp-3025	226	23	aβ	aβ	NOUN
fnp-3025	226	24	burden	burden	NOUN
fnp-3025	226	25	[	[	X
fnp-3025	226	26	163	163	NUM
fnp-3025	226	27	]	]	PUNCT
fnp-3025	226	28	,	,	PUNCT
fnp-3025	226	29	even	even	ADV
fnp-3025	226	30	though	though	SCONJ
fnp-3025	226	31	the	the	DET
fnp-3025	226	32	amino	amino	NOUN
fnp-3025	226	33	acid	acid	NOUN
fnp-3025	226	34	sequence	sequence	NOUN
fnp-3025	226	35	is	be	AUX
fnp-3025	226	36	identical	identical	ADJ
fnp-3025	226	37	to	to	ADP
fnp-3025	226	38	that	that	PRON
fnp-3025	226	39	of	of	ADP
fnp-3025	226	40	humans	human	NOUN
fnp-3025	226	41	(	(	PUNCT
fnp-3025	226	42	see	see	VERB
fnp-3025	226	43	section	section	NOUN
fnp-3025	226	44	10	10	NUM
fnp-3025	226	45	)	)	PUNCT
fnp-3025	226	46	.	.	PUNCT
fnp-3025	227	1	(	(	PUNCT
fnp-3025	227	2	note	note	VERB
fnp-3025	227	3	that	that	SCONJ
fnp-3025	227	4	binding	bind	VERB
fnp-3025	227	5	of	of	ADP
fnp-3025	227	6	ligands	ligand	NOUN
fnp-3025	227	7	can	can	AUX
fnp-3025	227	8	vary	vary	VERB
fnp-3025	227	9	among	among	ADP
fnp-3025	227	10	humans	human	NOUN
fnp-3025	227	11	;	;	PUNCT
fnp-3025	227	12	for	for	ADP
fnp-3025	227	13	example	example	NOUN
fnp-3025	227	14	,	,	PUNCT
fnp-3025	227	15	a	a	DET
fnp-3025	227	16	case	case	NOUN
fnp-3025	227	17	of	of	ADP
fnp-3025	227	18	end	end	NOUN
fnp-3025	227	19	-	-	PUNCT
fnp-3025	227	20	stage	stage	NOUN
fnp-3025	227	21	ad	ad	NOUN
fnp-3025	227	22	has	have	AUX
fnp-3025	227	23	been	be	AUX
fnp-3025	227	24	reported	report	VERB
fnp-3025	227	25	with	with	ADP
fnp-3025	227	26	extraordinarily	extraordinarily	ADV
fnp-3025	227	27	high	high	ADJ
fnp-3025	227	28	aβ	aβ	NOUN
fnp-3025	227	29	load	load	NOUN
fnp-3025	227	30	,	,	PUNCT
fnp-3025	227	31	a	a	DET
fnp-3025	227	32	predominance	predominance	NOUN
fnp-3025	227	33	of	of	ADP
fnp-3025	227	34	aβ40	aβ40	PROPN
fnp-3025	227	35	,	,	PUNCT
fnp-3025	227	36	and	and	CCONJ
fnp-3025	227	37	minimal	minimal	ADJ
fnp-3025	227	38	high	high	ADJ
fnp-3025	227	39	-	-	PUNCT
fnp-3025	227	40	affinity	affinity	NOUN
fnp-3025	227	41	binding	binding	NOUN
fnp-3025	227	42	of	of	ADP
fnp-3025	227	43	pib	pib	NOUN
fnp-3025	227	44	[	[	X
fnp-3025	227	45	164	164	NUM
fnp-3025	227	46	]	]	PUNCT
fnp-3025	227	47	)	)	PUNCT
fnp-3025	227	48	.	.	PUNCT
fnp-3025	228	1	since	since	SCONJ
fnp-3025	228	2	neither	neither	CCONJ
fnp-3025	228	3	ad	ad	NOUN
fnp-3025	228	4	-	-	PUNCT
fnp-3025	228	5	like	like	ADJ
fnp-3025	228	6	tauopathy	tauopathy	NOUN
fnp-3025	228	7	nor	nor	CCONJ
fnp-3025	228	8	dementia	dementia	NOUN
fnp-3025	228	9	has	have	AUX
fnp-3025	228	10	been	be	AUX
fnp-3025	228	11	reported	report	VERB
fnp-3025	228	12	in	in	ADP
fnp-3025	228	13	nonhuman	nonhuman	ADJ
fnp-3025	228	14	primates	primate	NOUN
fnp-3025	228	15	[	[	X
fnp-3025	228	16	165	165	NUM
fnp-3025	228	17	]	]	PUNCT
fnp-3025	228	18	,	,	PUNCT
fnp-3025	228	19	comparative	comparative	ADJ
fnp-3025	228	20	analysis	analysis	NOUN
fnp-3025	228	21	of	of	ADP
fnp-3025	228	22	ligand	ligand	ADJ
fnp-3025	228	23	binding	bind	VERB
fnp-3025	228	24	could	could	AUX
fnp-3025	228	25	be	be	AUX
fnp-3025	228	26	useful	useful	ADJ
fnp-3025	228	27	in	in	ADP
fnp-3025	228	28	defining	define	VERB
fnp-3025	228	29	the	the	DET
fnp-3025	228	30	variant	variant	ADJ
fnp-3025	228	31	molecular	molecular	ADJ
fnp-3025	228	32	characteristics	characteristic	NOUN
fnp-3025	228	33	of	of	ADP
fnp-3025	228	34	aβ	aβ	NOUN
fnp-3025	228	35	deposits	deposit	NOUN
fnp-3025	228	36	and	and	CCONJ
fnp-3025	228	37	their	their	PRON
fnp-3025	228	38	relationship	relationship	NOUN
fnp-3025	228	39	to	to	ADP
fnp-3025	228	40	disease	disease	NOUN
fnp-3025	228	41	phenotype	phenotype	NOUN
fnp-3025	228	42	(	(	PUNCT
fnp-3025	228	43	see	see	VERB
fnp-3025	228	44	sections	section	NOUN
fnp-3025	228	45	5.2	5.2	NUM
fnp-3025	228	46	and	and	CCONJ
fnp-3025	228	47	10	10	NUM
fnp-3025	228	48	)	)	PUNCT
fnp-3025	228	49	.	.	PUNCT
fnp-3025	229	1	9	9	NUM
fnp-3025	229	2	in	in	ADP
fnp-3025	229	3	the	the	DET
fnp-3025	229	4	1920s	1920s	NUM
fnp-3025	229	5	,	,	PUNCT
fnp-3025	229	6	congo	congo	PROPN
fnp-3025	229	7	red	red	NOUN
fnp-3025	229	8	was	be	AUX
fnp-3025	229	9	introduced	introduce	VERB
fnp-3025	229	10	as	as	ADP
fnp-3025	229	11	an	an	DET
fnp-3025	229	12	in	in	ADP
fnp-3025	229	13	vivo	vivo	ADJ
fnp-3025	229	14	diagnostic	diagnostic	ADJ
fnp-3025	229	15	agent	agent	NOUN
fnp-3025	229	16	for	for	ADP
fnp-3025	229	17	non	non	ADJ
fnp-3025	229	18	-	-	ADJ
fnp-3025	229	19	cerebral	cerebral	ADJ
fnp-3025	229	20	amyloidosis	amyloidosis	NOUN
fnp-3025	229	21	.	.	PUNCT
fnp-3025	230	1	following	follow	VERB
fnp-3025	230	2	intravenous	intravenous	ADJ
fnp-3025	230	3	injection	injection	NOUN
fnp-3025	230	4	,	,	PUNCT
fnp-3025	230	5	the	the	DET
fnp-3025	230	6	rate	rate	NOUN
fnp-3025	230	7	at	at	ADP
fnp-3025	230	8	which	which	PRON
fnp-3025	230	9	congo	congo	NOUN
fnp-3025	230	10	red	red	NOUN
fnp-3025	230	11	was	be	AUX
fnp-3025	230	12	cleared	clear	VERB
fnp-3025	230	13	from	from	ADP
fnp-3025	230	14	the	the	DET
fnp-3025	230	15	blood	blood	NOUN
fnp-3025	230	16	was	be	AUX
fnp-3025	230	17	thought	think	VERB
fnp-3025	230	18	to	to	PART
fnp-3025	230	19	reflect	reflect	VERB
fnp-3025	230	20	amyloid	amyloid	NOUN
fnp-3025	230	21	burden	burden	NOUN
fnp-3025	230	22	in	in	ADP
fnp-3025	230	23	affected	affected	ADJ
fnp-3025	230	24	organs	organ	NOUN
fnp-3025	230	25	(	(	PUNCT
fnp-3025	230	26	the	the	PRON
fnp-3025	230	27	more	more	ADJ
fnp-3025	230	28	amyloid	amyloid	NOUN
fnp-3025	230	29	to	to	PART
fnp-3025	230	30	bind	bind	VERB
fnp-3025	230	31	the	the	DET
fnp-3025	230	32	dye	dye	NOUN
fnp-3025	230	33	,	,	PUNCT
fnp-3025	230	34	the	the	DET
fnp-3025	230	35	more	more	ADV
fnp-3025	230	36	rapid	rapid	ADJ
fnp-3025	230	37	its	its	PRON
fnp-3025	230	38	clearance	clearance	NOUN
fnp-3025	230	39	from	from	ADP
fnp-3025	230	40	blood	blood	NOUN
fnp-3025	230	41	)	)	PUNCT
fnp-3025	230	42	.	.	PUNCT
fnp-3025	231	1	for	for	ADP
fnp-3025	231	2	various	various	ADJ
fnp-3025	231	3	reasons	reason	NOUN
fnp-3025	231	4	,	,	PUNCT
fnp-3025	231	5	the	the	DET
fnp-3025	231	6	test	test	NOUN
fnp-3025	231	7	never	never	ADV
fnp-3025	231	8	achieved	achieve	VERB
fnp-3025	231	9	widespread	widespread	ADJ
fnp-3025	231	10	use	use	NOUN
fnp-3025	231	11	(	(	PUNCT
fnp-3025	231	12	see	see	VERB
fnp-3025	231	13	buxbaum	buxbaum	NOUN
fnp-3025	231	14	and	and	CCONJ
fnp-3025	231	15	linke	linke	VERB
fnp-3025	231	16	[	[	PRON
fnp-3025	231	17	2012	2012	NUM
fnp-3025	231	18	]	]	PUNCT
fnp-3025	232	1	[	[	X
fnp-3025	232	2	reference	reference	NOUN
fnp-3025	232	3	52	52	NUM
fnp-3025	232	4	]	]	PUNCT
fnp-3025	232	5	)	)	PUNCT
fnp-3025	232	6	.	.	PUNCT
fnp-3025	233	1	5	5	X
fnp-3025	233	2	.	.	X
fnp-3025	233	3	the	the	DET
fnp-3025	233	4	variety	variety	NOUN
fnp-3025	233	5	of	of	ADP
fnp-3025	233	6	aβ	aβ	PRON
fnp-3025	233	7	deposits	deposit	NOUN
fnp-3025	233	8	5.1	5.1	NUM
fnp-3025	234	1	aβ	aβ	NOUN
fnp-3025	234	2	plaques	plaque	VERB
fnp-3025	234	3	the	the	DET
fnp-3025	234	4	histologic	histologic	ADJ
fnp-3025	234	5	implementation	implementation	NOUN
fnp-3025	234	6	of	of	ADP
fnp-3025	234	7	specific	specific	ADJ
fnp-3025	234	8	antibodies	antibody	NOUN
fnp-3025	234	9	in	in	ADP
fnp-3025	234	10	the	the	DET
fnp-3025	234	11	1980s	1980s	NUM
fnp-3025	234	12	firmly	firmly	ADV
fnp-3025	234	13	established	establish	VERB
fnp-3025	234	14	that	that	SCONJ
fnp-3025	234	15	aβ	aβ	PRON
fnp-3025	234	16	plaques	plaque	NOUN
fnp-3025	234	17	in	in	ADP
fnp-3025	234	18	the	the	DET
fnp-3025	234	19	brains	brain	NOUN
fnp-3025	234	20	of	of	ADP
fnp-3025	234	21	alzheimer	alzheimer	PROPN
fnp-3025	234	22	patients	patient	NOUN
fnp-3025	234	23	comprise	comprise	VERB
fnp-3025	234	24	a	a	DET
fnp-3025	234	25	remarkable	remarkable	ADJ
fnp-3025	234	26	variety	variety	NOUN
fnp-3025	234	27	of	of	ADP
fnp-3025	234	28	morphologies	morphology	NOUN
fnp-3025	235	1	[	[	X
fnp-3025	235	2	143	143	NUM
fnp-3025	235	3	,	,	PUNCT
fnp-3025	235	4	166	166	NUM
fnp-3025	235	5	-	-	SYM
fnp-3025	235	6	172	172	NUM
fnp-3025	235	7	]	]	PUNCT
fnp-3025	235	8	.	.	PUNCT
fnp-3025	236	1	several	several	ADJ
fnp-3025	236	2	modern	modern	ADJ
fnp-3025	236	3	classification	classification	NOUN
fnp-3025	236	4	schemes	scheme	NOUN
fnp-3025	236	5	have	have	AUX
fnp-3025	236	6	been	be	AUX
fnp-3025	236	7	proposed	propose	VERB
fnp-3025	236	8	(	(	PUNCT
fnp-3025	236	9	e.g.	e.g.	ADV
fnp-3025	236	10	,	,	PUNCT
fnp-3025	236	11	[	[	X
fnp-3025	236	12	143	143	NUM
fnp-3025	236	13	,	,	PUNCT
fnp-3025	236	14	166	166	NUM
fnp-3025	236	15	,	,	PUNCT
fnp-3025	236	16	173	173	NUM
fnp-3025	236	17	-	-	SYM
fnp-3025	236	18	176	176	NUM
fnp-3025	236	19	]	]	PUNCT
fnp-3025	236	20	)	)	PUNCT
fnp-3025	236	21	,	,	PUNCT
fnp-3025	236	22	and	and	CCONJ
fnp-3025	236	23	while	while	SCONJ
fnp-3025	236	24	there	there	PRON
fnp-3025	236	25	is	be	VERB
fnp-3025	236	26	not	not	PART
fnp-3025	236	27	universal	universal	ADJ
fnp-3025	236	28	agreement	agreement	NOUN
fnp-3025	236	29	on	on	ADP
fnp-3025	236	30	some	some	PRON
fnp-3025	236	31	of	of	ADP
fnp-3025	236	32	the	the	DET
fnp-3025	236	33	terms	term	NOUN
fnp-3025	236	34	,	,	PUNCT
fnp-3025	236	35	aβ	aβ	DET
fnp-3025	236	36	plaques	plaque	NOUN
fnp-3025	236	37	can	can	AUX
fnp-3025	236	38	be	be	AUX
fnp-3025	236	39	broadly	broadly	ADV
fnp-3025	236	40	categorized	categorize	VERB
fnp-3025	236	41	into	into	ADP
fnp-3025	236	42	amyloid	amyloid	NOUN
fnp-3025	236	43	plaques	plaque	NOUN
fnp-3025	236	44	per	per	ADP
fnp-3025	236	45	se	se	X
fnp-3025	236	46	(	(	PUNCT
fnp-3025	236	47	with	with	ADP
fnp-3025	236	48	dense	dense	ADJ
fnp-3025	236	49	,	,	PUNCT
fnp-3025	236	50	congophilic	congophilic	ADJ
fnp-3025	236	51	cores	core	NOUN
fnp-3025	236	52	)	)	PUNCT
fnp-3025	236	53	,	,	PUNCT
fnp-3025	236	54	and	and	CCONJ
fnp-3025	236	55	a	a	DET
fnp-3025	236	56	range	range	NOUN
fnp-3025	236	57	of	of	ADP
fnp-3025	236	58	more	more	ADV
fnp-3025	236	59	loosely	loosely	ADV
fnp-3025	236	60	organized	organize	VERB
fnp-3025	236	61	deposits	deposit	NOUN
fnp-3025	236	62	of	of	ADP
fnp-3025	236	63	myriad	myriad	ADJ
fnp-3025	236	64	sizes	size	NOUN
fnp-3025	236	65	,	,	PUNCT
fnp-3025	236	66	shapes	shape	NOUN
fnp-3025	236	67	,	,	PUNCT
fnp-3025	236	68	densities	density	NOUN
fnp-3025	236	69	and	and	CCONJ
fnp-3025	236	70	locations	location	NOUN
fnp-3025	236	71	[	[	X
fnp-3025	236	72	133	133	NUM
fnp-3025	236	73	]	]	PUNCT
fnp-3025	236	74	(	(	PUNCT
fnp-3025	236	75	figures	figure	NOUN
fnp-3025	236	76	5	5	NUM
fnp-3025	236	77	,	,	PUNCT
fnp-3025	236	78	6	6	NUM
fnp-3025	236	79	,	,	PUNCT
fnp-3025	236	80	8	8	NUM
fnp-3025	236	81	,	,	PUNCT
fnp-3025	236	82	9	9	NUM
fnp-3025	236	83	)	)	PUNCT
fnp-3025	236	84	.	.	PUNCT
fnp-3025	237	1	it	it	PRON
fnp-3025	237	2	is	be	AUX
fnp-3025	237	3	noteworthy	noteworthy	ADJ
fnp-3025	237	4	that	that	SCONJ
fnp-3025	237	5	different	different	ADJ
fnp-3025	237	6	genetic	genetic	ADJ
fnp-3025	237	7	mutations	mutation	NOUN
fnp-3025	237	8	can	can	AUX
fnp-3025	237	9	be	be	AUX
fnp-3025	237	10	associated	associate	VERB
fnp-3025	237	11	with	with	ADP
fnp-3025	237	12	particular	particular	ADJ
fnp-3025	237	13	predominant	predominant	ADJ
fnp-3025	237	14	plaque	plaque	NOUN
fnp-3025	237	15	morphologies	morphology	NOUN
fnp-3025	237	16	,	,	PUNCT
fnp-3025	237	17	as	as	ADV
fnp-3025	237	18	well	well	ADV
fnp-3025	237	19	as	as	ADP
fnp-3025	237	20	the	the	DET
fnp-3025	237	21	presence	presence	NOUN
fnp-3025	237	22	of	of	ADP
fnp-3025	237	23	caa	caa	NOUN
fnp-3025	237	24	(	(	PUNCT
fnp-3025	237	25	see	see	VERB
fnp-3025	237	26	alzforum	alzforum	NOUN
fnp-3025	237	27	for	for	ADP
fnp-3025	237	28	a	a	DET
fnp-3025	237	29	list	list	NOUN
fnp-3025	237	30	of	of	ADP
fnp-3025	237	31	alzheimer	alzheimer	PROPN
fnp-3025	237	32	-	-	PUNCT
fnp-3025	237	33	associated	associate	VERB
fnp-3025	237	34	mutations	mutation	NOUN
fnp-3025	237	35	(	(	PUNCT
fnp-3025	237	36	https://www.alzforum.org/mutations	https://www.alzforum.org/mutation	NOUN
fnp-3025	237	37	)	)	PUNCT
fnp-3025	237	38	.	.	PUNCT
fnp-3025	238	1	note	note	VERB
fnp-3025	238	2	also	also	ADV
fnp-3025	238	3	that	that	SCONJ
fnp-3025	238	4	relatively	relatively	ADV
fnp-3025	238	5	few	few	ADJ
fnp-3025	238	6	of	of	ADP
fnp-3025	238	7	the	the	DET
fnp-3025	238	8	mutant	mutant	ADJ
fnp-3025	238	9	forms	form	NOUN
fnp-3025	238	10	of	of	ADP
fnp-3025	238	11	ad	ad	NOUN
fnp-3025	238	12	have	have	AUX
fnp-3025	238	13	been	be	AUX
fnp-3025	238	14	thoroughly	thoroughly	ADV
fnp-3025	238	15	scrutinized	scrutinize	VERB
fnp-3025	238	16	neuropathologically	neuropathologically	ADV
fnp-3025	238	17	.	.	PUNCT
fnp-3025	239	1	within	within	ADP
fnp-3025	239	2	the	the	DET
fnp-3025	239	3	general	general	ADJ
fnp-3025	239	4	categories	category	NOUN
fnp-3025	239	5	of	of	ADP
fnp-3025	239	6	plaque	plaque	NOUN
fnp-3025	239	7	structure	structure	NOUN
fnp-3025	239	8	,	,	PUNCT
fnp-3025	239	9	the	the	DET
fnp-3025	239	10	aβ	aβ	NOUN
fnp-3025	239	11	-	-	PUNCT
fnp-3025	239	12	amyloid	amyloid	NOUN
fnp-3025	239	13	plaques	plaque	NOUN
fnp-3025	239	14	are	be	AUX
fnp-3025	239	15	more	more	ADV
fnp-3025	239	16	or	or	CCONJ
fnp-3025	239	17	less	less	ADJ
fnp-3025	239	18	spheroidal	spheroidal	NOUN
fnp-3025	239	19	lesions	lesion	NOUN
fnp-3025	239	20	that	that	PRON
fnp-3025	239	21	include	include	VERB
fnp-3025	239	22	‘	'	PUNCT
fnp-3025	239	23	classical	classical	ADJ
fnp-3025	239	24	’	'	PUNCT
fnp-3025	239	25	or	or	CCONJ
fnp-3025	239	26	‘	'	PUNCT
fnp-3025	239	27	mature	mature	ADJ
fnp-3025	239	28	’	'	PUNCT
fnp-3025	239	29	plaques	plaque	NOUN
fnp-3025	239	30	and	and	CCONJ
fnp-3025	239	31	so	so	ADV
fnp-3025	239	32	-	-	PUNCT
fnp-3025	239	33	called	call	VERB
fnp-3025	239	34	‘	'	PUNCT
fnp-3025	239	35	burned	burn	VERB
fnp-3025	239	36	-	-	PUNCT
fnp-3025	239	37	out	out	NOUN
fnp-3025	239	38	’	'	PUNCT
fnp-3025	239	39	or	or	CCONJ
fnp-3025	239	40	‘	'	PUNCT
fnp-3025	239	41	compact	compact	ADJ
fnp-3025	239	42	’	'	PUNCT
fnp-3025	239	43	plaques	plaque	NOUN
fnp-3025	239	44	[	[	X
fnp-3025	239	45	177	177	NUM
fnp-3025	239	46	,	,	PUNCT
fnp-3025	239	47	178	178	NUM
fnp-3025	239	48	]	]	PUNCT
fnp-3025	239	49	.	.	PUNCT
fnp-3025	240	1	recently	recently	ADV
fnp-3025	240	2	,	,	PUNCT
fnp-3025	240	3	a	a	DET
fnp-3025	240	4	‘	'	PUNCT
fnp-3025	240	5	coarse	coarse	ADJ
fnp-3025	240	6	-	-	PUNCT
fnp-3025	240	7	grain	grain	NOUN
fnp-3025	240	8	’	'	PUNCT
fnp-3025	240	9	plaque	plaque	NOUN
fnp-3025	240	10	type	type	NOUN
fnp-3025	240	11	with	with	ADP
fnp-3025	240	12	multiple	multiple	ADJ
fnp-3025	240	13	small	small	ADJ
fnp-3025	240	14	cores	core	NOUN
fnp-3025	240	15	and	and	CCONJ
fnp-3025	240	16	a	a	DET
fnp-3025	240	17	predominance	predominance	NOUN
fnp-3025	240	18	of	of	ADP
fnp-3025	240	19	aβ40	aβ40	PROPN
fnp-3025	240	20	has	have	AUX
fnp-3025	240	21	been	be	AUX
fnp-3025	240	22	described	describe	VERB
fnp-3025	240	23	in	in	ADP
fnp-3025	240	24	advanced	advanced	ADJ
fnp-3025	240	25	ad	ad	NOUN
fnp-3025	240	26	cases	case	NOUN
fnp-3025	240	27	,	,	PUNCT
fnp-3025	240	28	often	often	ADV
fnp-3025	240	29	in	in	ADP
fnp-3025	240	30	association	association	NOUN
fnp-3025	240	31	with	with	ADP
fnp-3025	240	32	apoe4	apoe4	PROPN
fnp-3025	240	33	homozygosity	homozygosity	NOUN
fnp-3025	240	34	and	and	CCONJ
fnp-3025	240	35	caa	caa	NOUN
fnp-3025	240	36	[	[	X
fnp-3025	240	37	179	179	NUM
fnp-3025	240	38	]	]	PUNCT
fnp-3025	240	39	.	.	PUNCT
fnp-3025	241	1	diffuse	diffuse	VERB
fnp-3025	241	2	aβ	aβ	DET
fnp-3025	241	3	plaques	plaque	NOUN
fnp-3025	241	4	are	be	AUX
fnp-3025	241	5	much	much	ADV
fnp-3025	241	6	more	more	ADV
fnp-3025	241	7	numerous	numerous	ADJ
fnp-3025	241	8	than	than	SCONJ
fnp-3025	241	9	are	be	AUX
fnp-3025	241	10	amyloid	amyloid	NOUN
fnp-3025	241	11	plaques	plaque	NOUN
fnp-3025	241	12	in	in	ADP
fnp-3025	241	13	the	the	DET
fnp-3025	241	14	alzheimeric	alzheimeric	ADJ
fnp-3025	241	15	brain	brain	NOUN
fnp-3025	242	1	[	[	X
fnp-3025	242	2	143	143	NUM
fnp-3025	242	3	]	]	PUNCT
fnp-3025	242	4	(	(	PUNCT
fnp-3025	242	5	figures	figure	NOUN
fnp-3025	242	6	6	6	NUM
fnp-3025	242	7	,	,	PUNCT
fnp-3025	242	8	8)	8)	NUM
fnp-3025	242	9	,	,	PUNCT
fnp-3025	242	10	and	and	CCONJ
fnp-3025	242	11	they	they	PRON
fnp-3025	242	12	span	span	VERB
fnp-3025	242	13	a	a	DET
fnp-3025	242	14	range	range	NOUN
fnp-3025	242	15	of	of	ADP
fnp-3025	242	16	compactness	compactness	NOUN
fnp-3025	242	17	from	from	ADP
fnp-3025	242	18	vaguely	vaguely	ADV
fnp-3025	242	19	aβ	aβ	NOUN
fnp-3025	242	20	-	-	PUNCT
fnp-3025	242	21	immunoreactive	immunoreactive	ADJ
fnp-3025	242	22	,	,	PUNCT
fnp-3025	242	23	congo	congo	ADJ
fnp-3025	242	24	red	red	ADJ
fnp-3025	242	25	-	-	PUNCT
fnp-3025	242	26	negative	negative	ADJ
fnp-3025	242	27	regions	region	NOUN
fnp-3025	242	28	(	(	PUNCT
fnp-3025	242	29	e.g.	e.g.	ADV
fnp-3025	242	30	,	,	PUNCT
fnp-3025	242	31	‘	'	PUNCT
fnp-3025	242	32	fleecy	fleecy	NOUN
fnp-3025	242	33	’	'	PUNCT
fnp-3025	242	34	plaques	plaque	NOUN
fnp-3025	242	35	[	[	X
fnp-3025	242	36	180	180	NUM
fnp-3025	242	37	]	]	PUNCT
fnp-3025	242	38	)	)	PUNCT
fnp-3025	242	39	to	to	ADP
fnp-3025	242	40	clusters	cluster	NOUN
fnp-3025	242	41	of	of	ADP
fnp-3025	242	42	loose	loose	ADJ
fnp-3025	242	43	fibrillar	fibrillar	ADJ
fnp-3025	242	44	material	material	NOUN
fnp-3025	242	45	that	that	PRON
fnp-3025	242	46	sometimes	sometimes	ADV
fnp-3025	242	47	are	be	AUX
fnp-3025	242	48	weakly	weakly	ADV
fnp-3025	242	49	congophilic	congophilic	ADJ
fnp-3025	243	1	[	[	X
fnp-3025	243	2	139	139	NUM
fnp-3025	243	3	,	,	PUNCT
fnp-3025	243	4	166	166	NUM
fnp-3025	243	5	]	]	PUNCT
fnp-3025	243	6	.	.	PUNCT
fnp-3025	244	1	ultrastructurally	ultrastructurally	ADV
fnp-3025	244	2	,	,	PUNCT
fnp-3025	244	3	some	some	PRON
fnp-3025	244	4	of	of	ADP
fnp-3025	244	5	these	these	DET
fnp-3025	244	6	diffuse	diffuse	NOUN
fnp-3025	244	7	deposits	deposit	NOUN
fnp-3025	244	8	have	have	AUX
fnp-3025	244	9	been	be	AUX
fnp-3025	244	10	shown	show	VERB
fnp-3025	244	11	to	to	PART
fnp-3025	244	12	include	include	VERB
fnp-3025	244	13	amyloid	amyloid	NOUN
fnp-3025	244	14	fibrils	fibril	NOUN
fnp-3025	244	15	[	[	X
fnp-3025	244	16	181	181	NUM
fnp-3025	244	17	-	-	SYM
fnp-3025	244	18	183	183	NUM
fnp-3025	244	19	]	]	PUNCT
fnp-3025	244	20	,	,	PUNCT
fnp-3025	244	21	whereas	whereas	SCONJ
fnp-3025	244	22	others	other	NOUN
fnp-3025	244	23	do	do	VERB
fnp-3025	244	24	not	not	PART
fnp-3025	245	1	[	[	X
fnp-3025	245	2	183	183	NUM
fnp-3025	245	3	]	]	PUNCT
fnp-3025	245	4	,	,	PUNCT
fnp-3025	245	5	the	the	DET
fnp-3025	245	6	latter	latter	NOUN
fnp-3025	245	7	possibly	possibly	ADV
fnp-3025	245	8	representing	represent	VERB
fnp-3025	245	9	a	a	DET
fnp-3025	245	10	pre	pre	ADJ
fnp-3025	245	11	-	-	ADJ
fnp-3025	245	12	amyloid	amyloid	ADJ
fnp-3025	245	13	stage	stage	NOUN
fnp-3025	245	14	of	of	ADP
fnp-3025	245	15	aβ	aβ	DET
fnp-3025	245	16	aggregation	aggregation	NOUN
fnp-3025	245	17	[	[	X
fnp-3025	245	18	139	139	NUM
fnp-3025	245	19	]	]	PUNCT
fnp-3025	245	20	.	.	PUNCT
fnp-3025	246	1	figure	figure	NOUN
fnp-3025	246	2	8	8	NUM
fnp-3025	246	3	.	.	PUNCT
fnp-3025	247	1	small	small	ADJ
fnp-3025	247	2	,	,	PUNCT
fnp-3025	247	3	often	often	ADV
fnp-3025	247	4	stellate	stellate	VERB
fnp-3025	247	5	aβ	aβ	ADP
fnp-3025	247	6	deposits	deposit	NOUN
fnp-3025	247	7	in	in	ADP
fnp-3025	247	8	the	the	DET
fnp-3025	247	9	cortex	cortex	NOUN
fnp-3025	247	10	of	of	ADP
fnp-3025	247	11	an	an	DET
fnp-3025	247	12	ad	ad	NOUN
fnp-3025	247	13	patient	patient	NOUN
fnp-3025	247	14	.	.	PUNCT
fnp-3025	248	1	some	some	DET
fnp-3025	248	2	aβ	aβ	VERB
fnp-3025	248	3	accumulates	accumulate	VERB
fnp-3025	248	4	within	within	ADP
fnp-3025	248	5	glial	glial	ADJ
fnp-3025	248	6	cells	cell	NOUN
fnp-3025	248	7	,	,	PUNCT
fnp-3025	248	8	most	most	ADV
fnp-3025	248	9	likely	likely	ADJ
fnp-3025	248	10	astrocytes	astrocyte	NOUN
fnp-3025	248	11	(	(	PUNCT
fnp-3025	248	12	right	right	ADJ
fnp-3025	248	13	)	)	PUNCT
fnp-3025	248	14	.	.	PUNCT
fnp-3025	249	1	antibody	antibody	NOUN
fnp-3025	249	2	4g8	4g8	NUM
fnp-3025	249	3	;	;	PUNCT
fnp-3025	249	4	nissl	nissl	ADJ
fnp-3025	249	5	counterstain	counterstain	PROPN
fnp-3025	249	6	.	.	PUNCT
fnp-3025	250	1	bars	bar	NOUN
fnp-3025	250	2	=	=	NOUN
fnp-3025	250	3	20μm	20μm	NOUN
fnp-3025	250	4	.	.	PUNCT
fnp-3025	251	1	figure	figure	NOUN
fnp-3025	251	2	9	9	NUM
fnp-3025	251	3	.	.	PUNCT
fnp-3025	252	1	band	band	NOUN
fnp-3025	252	2	-	-	PUNCT
fnp-3025	252	3	like	like	ADJ
fnp-3025	252	4	subpial	subpial	ADJ
fnp-3025	252	5	aβ	aβ	INTJ
fnp-3025	252	6	(	(	PUNCT
fnp-3025	252	7	left	left	ADJ
fnp-3025	252	8	)	)	PUNCT
fnp-3025	252	9	in	in	ADP
fnp-3025	252	10	neocortical	neocortical	ADJ
fnp-3025	252	11	layer	layer	NOUN
fnp-3025	252	12	1	1	NUM
fnp-3025	252	13	and	and	CCONJ
fnp-3025	252	14	presubicular	presubicular	PROPN
fnp-3025	252	15	lake	lake	NOUN
fnp-3025	252	16	-	-	PUNCT
fnp-3025	252	17	like	like	ADJ
fnp-3025	252	18	aβ	aβ	NOUN
fnp-3025	252	19	(	(	PUNCT
fnp-3025	252	20	right	right	NOUN
fnp-3025	252	21	)	)	PUNCT
fnp-3025	252	22	from	from	ADP
fnp-3025	252	23	two	two	NUM
fnp-3025	252	24	cases	case	NOUN
fnp-3025	252	25	of	of	ADP
fnp-3025	252	26	ad	ad	NOUN
fnp-3025	252	27	.	.	PUNCT
fnp-3025	253	1	the	the	DET
fnp-3025	253	2	subpial	subpial	ADJ
fnp-3025	253	3	aβ	aβ	NOUN
fnp-3025	253	4	can	can	AUX
fnp-3025	253	5	be	be	AUX
fnp-3025	253	6	discontinuous	discontinuous	ADJ
fnp-3025	253	7	,	,	PUNCT
fnp-3025	253	8	confluent	confluent	ADJ
fnp-3025	253	9	,	,	PUNCT
fnp-3025	253	10	or	or	CCONJ
fnp-3025	253	11	punctate	punctate	NOUN
fnp-3025	253	12	.	.	PUNCT
fnp-3025	254	1	antibodies	antibodie	VERB
fnp-3025	254	2	4g8	4g8	NUM
fnp-3025	254	3	(	(	PUNCT
fnp-3025	254	4	left	leave	VERB
fnp-3025	254	5	)	)	PUNCT
fnp-3025	254	6	and	and	CCONJ
fnp-3025	254	7	6e10	6e10	NOUN
fnp-3025	254	8	(	(	PUNCT
fnp-3025	254	9	right	right	ADJ
fnp-3025	254	10	)	)	PUNCT
fnp-3025	254	11	;	;	PUNCT
fnp-3025	254	12	nissl	nissl	ADJ
fnp-3025	254	13	counterstain	counterstain	NOUN
fnp-3025	254	14	.	.	PUNCT
fnp-3025	255	1	bar	bar	NOUN
fnp-3025	255	2	=	=	SYM
fnp-3025	255	3	100μm	100μm	PROPN
fnp-3025	255	4	for	for	ADP
fnp-3025	255	5	both	both	DET
fnp-3025	255	6	images	image	NOUN
fnp-3025	255	7	.	.	PUNCT
fnp-3025	256	1	diffuse	diffuse	VERB
fnp-3025	256	2	aβ	aβ	NOUN
fnp-3025	256	3	plaques	plaque	NOUN
fnp-3025	256	4	comprise	comprise	VERB
fnp-3025	256	5	very	very	ADV
fnp-3025	256	6	small	small	ADJ
fnp-3025	256	7	,	,	PUNCT
fnp-3025	256	8	often	often	ADV
fnp-3025	256	9	stellate	stellate	ADJ
fnp-3025	256	10	assemblies	assembly	NOUN
fnp-3025	256	11	scattered	scatter	VERB
fnp-3025	256	12	about	about	ADP
fnp-3025	256	13	the	the	DET
fnp-3025	256	14	parenchyma	parenchyma	NOUN
fnp-3025	256	15	(	(	PUNCT
fnp-3025	256	16	figure	figure	NOUN
fnp-3025	256	17	8)	8)	NUM
fnp-3025	256	18	,	,	PUNCT
fnp-3025	256	19	a	a	DET
fnp-3025	256	20	sheet	sheet	NOUN
fnp-3025	256	21	-	-	PUNCT
fnp-3025	256	22	like	like	ADJ
fnp-3025	256	23	band	band	NOUN
fnp-3025	256	24	of	of	ADP
fnp-3025	256	25	sometimes	sometimes	ADV
fnp-3025	256	26	confluent	confluent	ADJ
fnp-3025	256	27	,	,	PUNCT
fnp-3025	256	28	sometimes	sometimes	ADV
fnp-3025	256	29	patchy	patchy	ADJ
fnp-3025	256	30	material	material	NOUN
fnp-3025	256	31	in	in	ADP
fnp-3025	256	32	the	the	DET
fnp-3025	256	33	subpial	subpial	ADJ
fnp-3025	256	34	cortex	cortex	NOUN
fnp-3025	256	35	(	(	PUNCT
fnp-3025	256	36	figure	figure	NOUN
fnp-3025	256	37	9	9	NUM
fnp-3025	256	38	)	)	PUNCT
fnp-3025	256	39	,	,	PUNCT
fnp-3025	256	40	large	large	ADJ
fnp-3025	256	41	‘	'	PUNCT
fnp-3025	256	42	cotton	cotton	NOUN
fnp-3025	256	43	-	-	PUNCT
fnp-3025	256	44	wool	wool	NOUN
fnp-3025	256	45	’	'	PUNCT
fnp-3025	256	46	plaques	plaque	NOUN
fnp-3025	256	47	,	,	PUNCT
fnp-3025	256	48	and	and	CCONJ
fnp-3025	256	49	very	very	ADV
fnp-3025	256	50	large	large	ADJ
fnp-3025	256	51	‘	'	PUNCT
fnp-3025	256	52	lake	lake	NOUN
fnp-3025	256	53	-	-	PUNCT
fnp-3025	256	54	like	like	ADJ
fnp-3025	256	55	’	'	PUNCT
fnp-3025	256	56	patches	patch	NOUN
fnp-3025	256	57	,	,	PUNCT
fnp-3025	256	58	including	include	VERB
fnp-3025	256	59	a	a	DET
fnp-3025	256	60	distinctive	distinctive	ADJ
fnp-3025	256	61	cribriform	cribriform	NOUN
fnp-3025	256	62	deposit	deposit	NOUN
fnp-3025	256	63	in	in	ADP
fnp-3025	256	64	the	the	DET
fnp-3025	256	65	subicular	subicular	ADJ
fnp-3025	256	66	complex	complex	NOUN
fnp-3025	257	1	[	[	X
fnp-3025	257	2	143	143	NUM
fnp-3025	257	3	,	,	PUNCT
fnp-3025	257	4	171	171	NUM
fnp-3025	257	5	,	,	PUNCT
fnp-3025	257	6	176	176	NUM
fnp-3025	257	7	,	,	PUNCT
fnp-3025	257	8	184	184	NUM
fnp-3025	257	9	]	]	PUNCT
fnp-3025	257	10	(	(	PUNCT
fnp-3025	257	11	figure	figure	NOUN
fnp-3025	257	12	9	9	NUM
fnp-3025	257	13	)	)	PUNCT
fnp-3025	257	14	.	.	PUNCT
fnp-3025	258	1	abnormal	abnormal	ADJ
fnp-3025	258	2	neurites	neurite	NOUN
fnp-3025	258	3	generally	generally	ADV
fnp-3025	258	4	are	be	AUX
fnp-3025	258	5	absent	absent	ADJ
fnp-3025	258	6	or	or	CCONJ
fnp-3025	258	7	sparse	sparse	ADJ
fnp-3025	258	8	in	in	ADP
fnp-3025	258	9	diffuse	diffuse	ADJ
fnp-3025	258	10	deposits	deposit	NOUN
fnp-3025	258	11	[	[	X
fnp-3025	258	12	139	139	NUM
fnp-3025	258	13	]	]	PUNCT
fnp-3025	258	14	,	,	PUNCT
fnp-3025	258	15	and	and	CCONJ
fnp-3025	258	16	this	this	PRON
fnp-3025	258	17	includes	include	VERB
fnp-3025	258	18	the	the	DET
fnp-3025	258	19	cotton	cotton	NOUN
fnp-3025	258	20	-	-	PUNCT
fnp-3025	258	21	wool	wool	NOUN
fnp-3025	258	22	plaques	plaque	NOUN
fnp-3025	258	23	that	that	PRON
fnp-3025	258	24	are	be	AUX
fnp-3025	258	25	characteristic	characteristic	ADJ
fnp-3025	258	26	of	of	ADP
fnp-3025	258	27	some	some	DET
fnp-3025	258	28	advanced	advanced	ADJ
fnp-3025	258	29	ad	ad	NOUN
fnp-3025	258	30	cases	case	NOUN
fnp-3025	258	31	[	[	X
fnp-3025	258	32	90	90	NUM
fnp-3025	258	33	-	-	SYM
fnp-3025	258	34	94	94	NUM
fnp-3025	258	35	,	,	PUNCT
fnp-3025	258	36	134	134	NUM
fnp-3025	258	37	]	]	PUNCT
fnp-3025	258	38	.	.	PUNCT
fnp-3025	259	1	despite	despite	SCONJ
fnp-3025	259	2	their	their	PRON
fnp-3025	259	3	abundance	abundance	NOUN
fnp-3025	259	4	in	in	ADP
fnp-3025	259	5	the	the	DET
fnp-3025	259	6	alzheimeric	alzheimeric	ADJ
fnp-3025	259	7	brain	brain	NOUN
fnp-3025	259	8	,	,	PUNCT
fnp-3025	259	9	very	very	ADV
fnp-3025	259	10	small	small	ADJ
fnp-3025	259	11	diffuse	diffuse	NOUN
fnp-3025	259	12	deposits	deposit	NOUN
fnp-3025	259	13	have	have	AUX
fnp-3025	259	14	received	receive	VERB
fnp-3025	259	15	remarkably	remarkably	ADV
fnp-3025	259	16	little	little	ADJ
fnp-3025	259	17	scientific	scientific	ADJ
fnp-3025	259	18	attention	attention	NOUN
fnp-3025	259	19	[	[	X
fnp-3025	259	20	175	175	NUM
fnp-3025	259	21	]	]	PUNCT
fnp-3025	259	22	.	.	PUNCT
fnp-3025	260	1	these	these	PRON
fnp-3025	260	2	probably	probably	ADV
fnp-3025	260	3	correspond	correspond	VERB
fnp-3025	260	4	to	to	ADP
fnp-3025	260	5	the	the	DET
fnp-3025	260	6	small	small	ADJ
fnp-3025	260	7	(	(	PUNCT
fnp-3025	260	8	~2μm	~2μm	NUM
fnp-3025	260	9	diameter	diameter	NOUN
fnp-3025	260	10	)	)	PUNCT
fnp-3025	260	11	‘	'	PUNCT
fnp-3025	260	12	sternchen	sternchen	ADV
fnp-3025	260	13	’	'	PUNCT
fnp-3025	260	14	which	which	PRON
fnp-3025	260	15	fischer	fischer	NOUN
fnp-3025	260	16	in	in	ADP
fnp-3025	260	17	1910	1910	NUM
fnp-3025	260	18	considered	consider	VERB
fnp-3025	260	19	to	to	PART
fnp-3025	260	20	be	be	AUX
fnp-3025	260	21	the	the	DET
fnp-3025	260	22	first	first	ADJ
fnp-3025	260	23	stage	stage	NOUN
fnp-3025	260	24	of	of	ADP
fnp-3025	260	25	plaque	plaque	NOUN
fnp-3025	260	26	formation	formation	NOUN
fnp-3025	261	1	[	[	X
fnp-3025	261	2	185	185	NUM
fnp-3025	261	3	]	]	PUNCT
fnp-3025	261	4	.	.	PUNCT
fnp-3025	262	1	at	at	ADP
fnp-3025	262	2	least	least	ADJ
fnp-3025	262	3	some	some	PRON
fnp-3025	262	4	of	of	ADP
fnp-3025	262	5	them	they	PRON
fnp-3025	262	6	appear	appear	VERB
fnp-3025	262	7	to	to	PART
fnp-3025	262	8	be	be	AUX
fnp-3025	262	9	related	relate	VERB
fnp-3025	262	10	to	to	ADP
fnp-3025	262	11	astrocytes	astrocyte	NOUN
fnp-3025	262	12	[	[	X
fnp-3025	262	13	175	175	NUM
fnp-3025	262	14	,	,	PUNCT
fnp-3025	262	15	186	186	NUM
fnp-3025	262	16	]	]	PUNCT
fnp-3025	262	17	(	(	PUNCT
fnp-3025	262	18	figure	figure	NOUN
fnp-3025	262	19	8)	8)	NUM
fnp-3025	262	20	,	,	PUNCT
fnp-3025	262	21	but	but	CCONJ
fnp-3025	262	22	the	the	DET
fnp-3025	262	23	absence	absence	NOUN
fnp-3025	262	24	of	of	ADP
fnp-3025	262	25	systematic	systematic	ADJ
fnp-3025	262	26	research	research	NOUN
fnp-3025	262	27	on	on	ADP
fnp-3025	262	28	these	these	DET
fnp-3025	262	29	ubiquitous	ubiquitous	ADJ
fnp-3025	262	30	lesions	lesion	NOUN
fnp-3025	262	31	currently	currently	ADV
fnp-3025	262	32	precludes	preclude	VERB
fnp-3025	262	33	meaningful	meaningful	ADJ
fnp-3025	262	34	consideration	consideration	NOUN
fnp-3025	262	35	of	of	ADP
fnp-3025	262	36	their	their	PRON
fnp-3025	262	37	involvement	involvement	NOUN
fnp-3025	262	38	in	in	ADP
fnp-3025	262	39	the	the	DET
fnp-3025	262	40	proteopathic	proteopathic	ADJ
fnp-3025	262	41	process	process	NOUN
fnp-3025	262	42	.	.	PUNCT
fnp-3025	263	1	similarly	similarly	ADV
fnp-3025	263	2	,	,	PUNCT
fnp-3025	263	3	the	the	DET
fnp-3025	263	4	immunoreactivity	immunoreactivity	NOUN
fnp-3025	263	5	of	of	ADP
fnp-3025	263	6	some	some	DET
fnp-3025	263	7	vestigial	vestigial	NOUN
fnp-3025	263	8	(	(	PUNCT
fnp-3025	263	9	extracellular	extracellular	ADJ
fnp-3025	263	10	)	)	PUNCT
fnp-3025	263	11	neurofibrillary	neurofibrillary	ADJ
fnp-3025	263	12	tangles	tangle	NOUN
fnp-3025	263	13	with	with	ADP
fnp-3025	263	14	antibodies	antibody	NOUN
fnp-3025	263	15	to	to	ADP
fnp-3025	263	16	aβ	aβ	PRON
fnp-3025	263	17	[	[	X
fnp-3025	263	18	187	187	NUM
fnp-3025	263	19	-	-	SYM
fnp-3025	263	20	194	194	NUM
fnp-3025	263	21	]	]	PUNCT
fnp-3025	263	22	(	(	PUNCT
fnp-3025	263	23	figure	figure	NOUN
fnp-3025	263	24	10	10	NUM
fnp-3025	263	25	)	)	PUNCT
fnp-3025	263	26	remains	remain	VERB
fnp-3025	263	27	mechanistically	mechanistically	ADV
fnp-3025	263	28	undefined	undefined	ADJ
fnp-3025	263	29	.	.	PUNCT
fnp-3025	264	1	figure	figure	NOUN
fnp-3025	264	2	10	10	NUM
fnp-3025	264	3	.	.	PUNCT
fnp-3025	265	1	neurofibrillary	neurofibrillary	ADJ
fnp-3025	265	2	tangles	tangle	NOUN
fnp-3025	265	3	in	in	ADP
fnp-3025	265	4	the	the	DET
fnp-3025	265	5	cortex	cortex	NOUN
fnp-3025	265	6	of	of	ADP
fnp-3025	265	7	an	an	DET
fnp-3025	265	8	ad	ad	NOUN
fnp-3025	265	9	patient	patient	NOUN
fnp-3025	265	10	immunostained	immunostaine	VERB
fnp-3025	265	11	with	with	ADP
fnp-3025	265	12	an	an	DET
fnp-3025	265	13	antibody	antibody	NOUN
fnp-3025	265	14	to	to	ADP
fnp-3025	265	15	aβ40	aβ40	PROPN
fnp-3025	265	16	.	.	PUNCT
fnp-3025	266	1	when	when	SCONJ
fnp-3025	266	2	present	present	ADJ
fnp-3025	266	3	,	,	PUNCT
fnp-3025	266	4	this	this	DET
fnp-3025	266	5	colocalization	colocalization	NOUN
fnp-3025	266	6	occurs	occur	VERB
fnp-3025	266	7	mostly	mostly	ADV
fnp-3025	266	8	on	on	ADP
fnp-3025	266	9	extracellular	extracellular	ADJ
fnp-3025	266	10	(	(	PUNCT
fnp-3025	266	11	'	'	PUNCT
fnp-3025	266	12	ghost	ghost	NOUN
fnp-3025	266	13	'	'	PUNCT
fnp-3025	266	14	)	)	PUNCT
fnp-3025	266	15	tangles	tangle	NOUN
fnp-3025	266	16	.	.	PUNCT
fnp-3025	267	1	nissl	nissl	ADJ
fnp-3025	267	2	counterstain	counterstain	NOUN
fnp-3025	267	3	.	.	PUNCT
fnp-3025	268	1	bar	bar	NOUN
fnp-3025	268	2	=	=	SYM
fnp-3025	268	3	50μm	50μm	NOUN
fnp-3025	268	4	.	.	PUNCT
fnp-3025	269	1	certain	certain	ADJ
fnp-3025	269	2	types	type	NOUN
fnp-3025	269	3	of	of	ADP
fnp-3025	269	4	aβ	aβ	NOUN
fnp-3025	269	5	plaque	plaque	NOUN
fnp-3025	269	6	are	be	AUX
fnp-3025	269	7	typical	typical	ADJ
fnp-3025	269	8	of	of	ADP
fnp-3025	269	9	the	the	DET
fnp-3025	269	10	brain	brain	NOUN
fnp-3025	269	11	compartments	compartment	NOUN
fnp-3025	269	12	in	in	ADP
fnp-3025	269	13	which	which	PRON
fnp-3025	269	14	they	they	PRON
fnp-3025	269	15	develop	develop	VERB
fnp-3025	269	16	,	,	PUNCT
fnp-3025	269	17	e.g.	e.g.	ADV
fnp-3025	269	18	,	,	PUNCT
fnp-3025	269	19	in	in	ADP
fnp-3025	269	20	the	the	DET
fnp-3025	269	21	cerebellum	cerebellum	NOUN
fnp-3025	269	22	,	,	PUNCT
fnp-3025	269	23	basal	basal	ADJ
fnp-3025	269	24	ganglia	ganglia	NOUN
fnp-3025	269	25	,	,	PUNCT
fnp-3025	269	26	or	or	CCONJ
fnp-3025	269	27	different	different	ADJ
fnp-3025	269	28	cortical	cortical	ADJ
fnp-3025	269	29	regions	region	NOUN
fnp-3025	269	30	and	and	CCONJ
fnp-3025	269	31	laminae	laminae	NOUN
fnp-3025	269	32	(	(	PUNCT
fnp-3025	269	33	see	see	VERB
fnp-3025	269	34	[	[	X
fnp-3025	269	35	139	139	NUM
fnp-3025	269	36	]	]	PUNCT
fnp-3025	269	37	)	)	PUNCT
fnp-3025	269	38	.	.	PUNCT
fnp-3025	270	1	in	in	ADP
fnp-3025	270	2	the	the	DET
fnp-3025	270	3	white	white	ADJ
fnp-3025	270	4	matter	matter	NOUN
fnp-3025	270	5	,	,	PUNCT
fnp-3025	270	6	distinctive	distinctive	ADJ
fnp-3025	270	7	granular	granular	ADJ
fnp-3025	270	8	accumulations	accumulation	NOUN
fnp-3025	270	9	of	of	ADP
fnp-3025	270	10	aβ	aβ	NOUN
fnp-3025	270	11	[	[	X
fnp-3025	270	12	143	143	NUM
fnp-3025	270	13	]	]	PUNCT
fnp-3025	270	14	occur	occur	VERB
fnp-3025	270	15	to	to	ADP
fnp-3025	270	16	varying	vary	VERB
fnp-3025	270	17	degrees	degree	NOUN
fnp-3025	270	18	(	(	PUNCT
fnp-3025	270	19	figure	figure	NOUN
fnp-3025	270	20	11	11	NUM
fnp-3025	270	21	)	)	PUNCT
fnp-3025	270	22	.	.	PUNCT
fnp-3025	271	1	these	these	DET
fnp-3025	271	2	clusters	cluster	NOUN
fnp-3025	271	3	consist	consist	VERB
fnp-3025	271	4	of	of	ADP
fnp-3025	271	5	fibrillar	fibrillar	ADJ
fnp-3025	271	6	aβ	aβ	NOUN
fnp-3025	271	7	lying	lie	VERB
fnp-3025	271	8	outside	outside	ADP
fnp-3025	271	9	of	of	ADP
fnp-3025	271	10	the	the	DET
fnp-3025	271	11	axons	axon	NOUN
fnp-3025	271	12	,	,	PUNCT
fnp-3025	271	13	and	and	CCONJ
fnp-3025	271	14	they	they	PRON
fnp-3025	271	15	appear	appear	VERB
fnp-3025	271	16	not	not	PART
fnp-3025	271	17	to	to	PART
fnp-3025	271	18	be	be	AUX
fnp-3025	271	19	associated	associate	VERB
fnp-3025	271	20	with	with	ADP
fnp-3025	271	21	obvious	obvious	ADJ
fnp-3025	271	22	tauopathy	tauopathy	NOUN
fnp-3025	271	23	or	or	CCONJ
fnp-3025	271	24	other	other	ADJ
fnp-3025	271	25	abnormalities	abnormality	NOUN
fnp-3025	271	26	of	of	ADP
fnp-3025	271	27	the	the	DET
fnp-3025	271	28	axons	axon	NOUN
fnp-3025	271	29	themselves	themselves	PRON
fnp-3025	272	1	[	[	X
fnp-3025	272	2	143	143	NUM
fnp-3025	272	3	]	]	X
fnp-3025	272	4	,	,	PUNCT
fnp-3025	272	5	although	although	SCONJ
fnp-3025	272	6	their	their	PRON
fnp-3025	272	7	functional	functional	ADJ
fnp-3025	272	8	significance	significance	NOUN
fnp-3025	272	9	is	be	AUX
fnp-3025	272	10	largely	largely	ADV
fnp-3025	272	11	unexplored	unexplored	ADJ
fnp-3025	272	12	.	.	PUNCT
fnp-3025	273	1	the	the	DET
fnp-3025	273	2	core	core	NOUN
fnp-3025	273	3	-	-	PUNCT
fnp-3025	273	4	space	space	NOUN
fnp-3025	273	5	-	-	PUNCT
fnp-3025	273	6	corona	corona	NOUN
fnp-3025	273	7	arrangement	arrangement	NOUN
fnp-3025	273	8	of	of	ADP
fnp-3025	273	9	aβ	aβ	NOUN
fnp-3025	273	10	is	be	AUX
fnp-3025	273	11	a	a	DET
fnp-3025	273	12	notable	notable	ADJ
fnp-3025	273	13	structural	structural	ADJ
fnp-3025	273	14	feature	feature	NOUN
fnp-3025	273	15	of	of	ADP
fnp-3025	273	16	classical	classical	ADJ
fnp-3025	273	17	aβ	aβ	NOUN
fnp-3025	273	18	plaques	plaque	NOUN
fnp-3025	273	19	that	that	PRON
fnp-3025	273	20	was	be	AUX
fnp-3025	273	21	noted	note	VERB
fnp-3025	273	22	in	in	ADP
fnp-3025	273	23	several	several	ADJ
fnp-3025	273	24	early	early	ADJ
fnp-3025	273	25	investigations	investigation	NOUN
fnp-3025	273	26	(	(	PUNCT
fnp-3025	273	27	reviewed	review	VERB
fnp-3025	273	28	in	in	ADP
fnp-3025	273	29	[	[	X
fnp-3025	273	30	116	116	NUM
fnp-3025	273	31	,	,	PUNCT
fnp-3025	273	32	119	119	NUM
fnp-3025	273	33	,	,	PUNCT
fnp-3025	273	34	120	120	NUM
fnp-3025	273	35	]	]	PUNCT
fnp-3025	273	36	)	)	PUNCT
fnp-3025	273	37	.	.	PUNCT
fnp-3025	274	1	these	these	DET
fnp-3025	274	2	subdivisions	subdivision	NOUN
fnp-3025	274	3	of	of	ADP
fnp-3025	274	4	plaques	plaque	NOUN
fnp-3025	274	5	have	have	AUX
fnp-3025	274	6	been	be	AUX
fnp-3025	274	7	given	give	VERB
fnp-3025	274	8	various	various	ADJ
fnp-3025	274	9	designations	designation	NOUN
fnp-3025	274	10	in	in	ADP
fnp-3025	274	11	the	the	DET
fnp-3025	274	12	early	early	ADJ
fnp-3025	274	13	literature	literature	NOUN
fnp-3025	274	14	,	,	PUNCT
fnp-3025	274	15	for	for	ADP
fnp-3025	274	16	instance	instance	NOUN
fnp-3025	274	17	zentrum	zentrum	PROPN
fnp-3025	274	18	or	or	CCONJ
fnp-3025	274	19	kern	kern	PROPN
fnp-3025	274	20	,	,	PUNCT
fnp-3025	274	21	hof	hof	NOUN
fnp-3025	274	22	,	,	PUNCT
fnp-3025	274	23	ring	ring	NOUN
fnp-3025	274	24	,	,	PUNCT
fnp-3025	274	25	etc.10	etc.10	NOUN
fnp-3025	274	26	in	in	ADP
fnp-3025	274	27	tissue	tissue	NOUN
fnp-3025	274	28	that	that	PRON
fnp-3025	274	29	has	have	AUX
fnp-3025	274	30	been	be	AUX
fnp-3025	274	31	immunostained	immunostaine	VERB
fnp-3025	274	32	for	for	ADP
fnp-3025	274	33	aβ	aβ	NOUN
fnp-3025	274	34	,	,	PUNCT
fnp-3025	274	35	classical	classical	ADJ
fnp-3025	274	36	aβ	aβ	DET
fnp-3025	274	37	plaques	plaque	NOUN
fnp-3025	274	38	have	have	VERB
fnp-3025	274	39	a	a	DET
fnp-3025	274	40	condensed	condense	VERB
fnp-3025	274	41	core	core	NOUN
fnp-3025	274	42	of	of	ADP
fnp-3025	274	43	aβ	aβ	NOUN
fnp-3025	274	44	-	-	PUNCT
fnp-3025	274	45	amyloid	amyloid	NOUN
fnp-3025	274	46	surrounded	surround	VERB
fnp-3025	274	47	by	by	ADP
fnp-3025	274	48	an	an	DET
fnp-3025	274	49	optically	optically	ADV
fnp-3025	274	50	clear	clear	ADJ
fnp-3025	274	51	region	region	NOUN
fnp-3025	274	52	with	with	ADP
fnp-3025	274	53	little	little	ADJ
fnp-3025	274	54	aβ	aβ	NOUN
fnp-3025	274	55	,	,	PUNCT
fnp-3025	274	56	and	and	CCONJ
fnp-3025	274	57	then	then	ADV
fnp-3025	274	58	an	an	DET
fnp-3025	274	59	outer	outer	ADJ
fnp-3025	274	60	corona	corona	NOUN
fnp-3025	274	61	of	of	ADP
fnp-3025	274	62	more	more	ADJ
fnp-3025	274	63	diffuse	diffuse	NOUN
fnp-3025	274	64	aβ	aβ	ADP
fnp-3025	275	1	[	[	X
fnp-3025	275	2	195	195	NUM
fnp-3025	275	3	]	]	PUNCT
fnp-3025	275	4	(	(	PUNCT
fnp-3025	275	5	see	see	VERB
fnp-3025	275	6	figure	figure	NOUN
fnp-3025	275	7	1	1	NUM
fnp-3025	275	8	)	)	PUNCT
fnp-3025	275	9	;	;	PUNCT
fnp-3025	275	10	the	the	DET
fnp-3025	275	11	relatively	relatively	ADV
fnp-3025	275	12	clear	clear	ADJ
fnp-3025	275	13	intermediate	intermediate	ADJ
fnp-3025	275	14	space	space	NOUN
fnp-3025	275	15	and	and	CCONJ
fnp-3025	275	16	the	the	DET
fnp-3025	275	17	outer	outer	ADJ
fnp-3025	275	18	corona	corona	NOUN
fnp-3025	275	19	are	be	AUX
fnp-3025	275	20	occupied	occupy	VERB
fnp-3025	275	21	by	by	ADP
fnp-3025	275	22	neuronal	neuronal	ADJ
fnp-3025	275	23	and	and	CCONJ
fnp-3025	275	24	glial	glial	ADJ
fnp-3025	275	25	elements	element	NOUN
fnp-3025	275	26	(	(	PUNCT
fnp-3025	275	27	which	which	PRON
fnp-3025	275	28	are	be	AUX
fnp-3025	275	29	considered	consider	VERB
fnp-3025	275	30	in	in	ADP
fnp-3025	275	31	more	more	ADJ
fnp-3025	275	32	detail	detail	NOUN
fnp-3025	275	33	in	in	ADP
fnp-3025	275	34	section	section	NOUN
fnp-3025	275	35	6	6	NUM
fnp-3025	275	36	)	)	PUNCT
fnp-3025	275	37	.	.	PUNCT
fnp-3025	276	1	figure	figure	VERB
fnp-3025	276	2	11	11	NUM
fnp-3025	276	3	.	.	PUNCT
fnp-3025	277	1	aβ	aβ	DET
fnp-3025	277	2	deposits	deposit	NOUN
fnp-3025	277	3	in	in	ADP
fnp-3025	277	4	white	white	ADJ
fnp-3025	277	5	matter	matter	NOUN
fnp-3025	277	6	of	of	ADP
fnp-3025	277	7	an	an	DET
fnp-3025	277	8	ad	ad	NOUN
fnp-3025	277	9	patient	patient	NOUN
fnp-3025	277	10	comprise	comprise	NOUN
fnp-3025	277	11	clusters	cluster	NOUN
fnp-3025	277	12	of	of	ADP
fnp-3025	277	13	small	small	ADJ
fnp-3025	277	14	puncta	puncta	NOUN
fnp-3025	277	15	and	and	CCONJ
fnp-3025	277	16	filamentous	filamentous	ADJ
fnp-3025	277	17	bundles	bundle	NOUN
fnp-3025	277	18	.	.	PUNCT
fnp-3025	278	1	left	leave	VERB
fnp-3025	278	2	:	:	PUNCT
fnp-3025	278	3	light	light	ADJ
fnp-3025	278	4	-	-	PUNCT
fnp-3025	278	5	micrograph	micrograph	NOUN
fnp-3025	278	6	of	of	ADP
fnp-3025	278	7	a	a	DET
fnp-3025	278	8	cluster	cluster	NOUN
fnp-3025	278	9	immunolabeled	immunolabele	VERB
fnp-3025	278	10	with	with	ADP
fnp-3025	278	11	antibody	antibody	NOUN
fnp-3025	278	12	4g8	4g8	NUM
fnp-3025	278	13	(	(	PUNCT
fnp-3025	278	14	nissl	nissl	ADJ
fnp-3025	278	15	counterstain	counterstain	NOUN
fnp-3025	278	16	)	)	PUNCT
fnp-3025	278	17	.	.	PUNCT
fnp-3025	279	1	right	right	INTJ
fnp-3025	279	2	,	,	PUNCT
fnp-3025	279	3	electron	electron	NOUN
fnp-3025	279	4	micrograph	micrograph	NOUN
fnp-3025	279	5	of	of	ADP
fnp-3025	279	6	a	a	DET
fnp-3025	279	7	punctum	punctum	NOUN
fnp-3025	279	8	immunolabeled	immunolabele	VERB
fnp-3025	279	9	with	with	ADP
fnp-3025	279	10	antibody	antibody	NOUN
fnp-3025	279	11	4g8	4g8	NUM
fnp-3025	279	12	(	(	PUNCT
fnp-3025	279	13	black	black	ADJ
fnp-3025	279	14	dots	dot	NOUN
fnp-3025	279	15	are	be	AUX
fnp-3025	279	16	gold	gold	ADJ
fnp-3025	279	17	particles	particle	NOUN
fnp-3025	279	18	bound	bind	VERB
fnp-3025	279	19	to	to	ADP
fnp-3025	279	20	the	the	DET
fnp-3025	279	21	secondary	secondary	ADJ
fnp-3025	279	22	antibody	antibody	NOUN
fnp-3025	279	23	)	)	PUNCT
fnp-3025	279	24	.	.	PUNCT
fnp-3025	280	1	bars	bar	NOUN
fnp-3025	281	1	=	=	SYM
fnp-3025	281	2	20μm	20μm	NOUN
fnp-3025	281	3	(	(	PUNCT
fnp-3025	281	4	left	left	ADJ
fnp-3025	281	5	)	)	PUNCT
fnp-3025	281	6	and	and	CCONJ
fnp-3025	281	7	200	200	NUM
fnp-3025	281	8	nm	nm	NOUN
fnp-3025	281	9	(	(	PUNCT
fnp-3025	281	10	right	right	NOUN
fnp-3025	281	11	)	)	PUNCT
fnp-3025	281	12	.	.	PUNCT
fnp-3025	282	1	viewed	view	VERB
fnp-3025	282	2	in	in	ADP
fnp-3025	282	3	the	the	DET
fnp-3025	282	4	electron	electron	NOUN
fnp-3025	282	5	microscope	microscope	NOUN
fnp-3025	282	6	,	,	PUNCT
fnp-3025	282	7	aβ	aβ	NOUN
fnp-3025	282	8	-	-	PUNCT
fnp-3025	282	9	amyloid	amyloid	NOUN
fnp-3025	282	10	fibrils	fibril	NOUN
fnp-3025	282	11	in	in	ADP
fnp-3025	282	12	the	the	DET
fnp-3025	282	13	plaque	plaque	NOUN
fnp-3025	282	14	core	core	NOUN
fnp-3025	282	15	are	be	AUX
fnp-3025	282	16	densely	densely	ADV
fnp-3025	282	17	packed	pack	VERB
fnp-3025	282	18	and	and	CCONJ
fnp-3025	282	19	often	often	ADV
fnp-3025	282	20	bundled	bundle	VERB
fnp-3025	282	21	to	to	PART
fnp-3025	282	22	form	form	VERB
fnp-3025	282	23	a	a	DET
fnp-3025	282	24	patchy	patchy	ADJ
fnp-3025	282	25	matrix	matrix	NOUN
fnp-3025	282	26	,	,	PUNCT
fnp-3025	282	27	and	and	CCONJ
fnp-3025	282	28	viable	viable	ADJ
fnp-3025	282	29	cellular	cellular	ADJ
fnp-3025	282	30	processes	process	NOUN
fnp-3025	282	31	there	there	PRON
fnp-3025	282	32	are	be	VERB
fnp-3025	282	33	largely	largely	ADV
fnp-3025	282	34	absent	absent	ADJ
fnp-3025	282	35	.	.	PUNCT
fnp-3025	283	1	the	the	DET
fnp-3025	283	2	more	more	ADV
fnp-3025	283	3	loosely	loosely	ADV
fnp-3025	283	4	organized	organize	VERB
fnp-3025	283	5	aβ	aβ	NOUN
fnp-3025	283	6	-	-	PUNCT
fnp-3025	283	7	amyloid	amyloid	NOUN
fnp-3025	283	8	sheaves	sheaf	NOUN
fnp-3025	283	9	in	in	ADP
fnp-3025	283	10	the	the	DET
fnp-3025	283	11	space	space	NOUN
fnp-3025	283	12	and	and	CCONJ
fnp-3025	283	13	corona	corona	NOUN
fnp-3025	283	14	interdigitate	interdigitate	NOUN
fnp-3025	283	15	with	with	ADP
fnp-3025	283	16	cellular	cellular	ADJ
fnp-3025	283	17	elements	element	NOUN
fnp-3025	283	18	such	such	ADJ
fnp-3025	283	19	as	as	ADP
fnp-3025	283	20	glial	glial	ADJ
fnp-3025	283	21	processes	process	NOUN
fnp-3025	283	22	and	and	CCONJ
fnp-3025	283	23	neurites	neurite	NOUN
fnp-3025	283	24	(	(	PUNCT
fnp-3025	283	25	figure	figure	NOUN
fnp-3025	283	26	12	12	NUM
fnp-3025	283	27	;	;	PUNCT
fnp-3025	283	28	see	see	VERB
fnp-3025	283	29	also	also	ADV
fnp-3025	283	30	figures	figure	VERB
fnp-3025	283	31	18	18	NUM
fnp-3025	283	32	and	and	CCONJ
fnp-3025	283	33	20	20	NUM
fnp-3025	283	34	)	)	PUNCT
fnp-3025	283	35	.	.	PUNCT
fnp-3025	284	1	embedded	embed	VERB
fnp-3025	284	2	in	in	ADP
fnp-3025	284	3	the	the	DET
fnp-3025	284	4	fibrillar	fibrillar	ADJ
fnp-3025	284	5	meshwork	meshwork	NOUN
fnp-3025	284	6	of	of	ADP
fnp-3025	284	7	amyloid	amyloid	NOUN
fnp-3025	284	8	in	in	ADP
fnp-3025	284	9	plaques	plaque	NOUN
fnp-3025	284	10	,	,	PUNCT
fnp-3025	284	11	various	various	ADJ
fnp-3025	284	12	small	small	ADJ
fnp-3025	284	13	,	,	PUNCT
fnp-3025	284	14	spherical	spherical	ADJ
fnp-3025	284	15	particles	particle	NOUN
fnp-3025	284	16	can	can	AUX
fnp-3025	284	17	be	be	AUX
fnp-3025	284	18	seen	see	VERB
fnp-3025	284	19	(	(	PUNCT
fnp-3025	284	20	figure	figure	NOUN
fnp-3025	284	21	13	13	NUM
fnp-3025	284	22	)	)	PUNCT
fnp-3025	284	23	.	.	PUNCT
fnp-3025	285	1	the	the	DET
fnp-3025	285	2	origin	origin	NOUN
fnp-3025	285	3	and	and	CCONJ
fnp-3025	285	4	significance	significance	NOUN
fnp-3025	285	5	of	of	ADP
fnp-3025	285	6	this	this	DET
fnp-3025	285	7	material	material	NOUN
fnp-3025	285	8	is	be	AUX
fnp-3025	285	9	obscure	obscure	ADJ
fnp-3025	285	10	,	,	PUNCT
fnp-3025	285	11	but	but	CCONJ
fnp-3025	285	12	it	it	PRON
fnp-3025	285	13	could	could	AUX
fnp-3025	285	14	account	account	VERB
fnp-3025	285	15	for	for	ADP
fnp-3025	285	16	some	some	PRON
fnp-3025	285	17	of	of	ADP
fnp-3025	285	18	the	the	DET
fnp-3025	285	19	non	non	ADJ
fnp-3025	285	20	-	-	ADJ
fnp-3025	285	21	aβ	aβ	ADJ
fnp-3025	285	22	substances	substance	NOUN
fnp-3025	285	23	that	that	PRON
fnp-3025	285	24	have	have	AUX
fnp-3025	285	25	been	be	AUX
fnp-3025	285	26	detected	detect	VERB
fnp-3025	285	27	in	in	ADP
fnp-3025	285	28	the	the	DET
fnp-3025	285	29	cores	core	NOUN
fnp-3025	285	30	of	of	ADP
fnp-3025	285	31	aβ	aβ	DET
fnp-3025	285	32	plaques	plaque	NOUN
fnp-3025	285	33	(	(	PUNCT
fnp-3025	285	34	see	see	VERB
fnp-3025	285	35	section	section	NOUN
fnp-3025	285	36	7	7	NUM
fnp-3025	285	37	)	)	PUNCT
fnp-3025	285	38	.	.	PUNCT
fnp-3025	286	1	one	one	NUM
fnp-3025	286	2	possibility	possibility	NOUN
fnp-3025	286	3	is	be	AUX
fnp-3025	286	4	that	that	SCONJ
fnp-3025	286	5	these	these	DET
fnp-3025	286	6	vesicles	vesicle	NOUN
fnp-3025	286	7	originate	originate	VERB
fnp-3025	286	8	from	from	ADP
fnp-3025	286	9	intracellular	intracellular	ADJ
fnp-3025	286	10	multivesicular	multivesicular	ADJ
fnp-3025	286	11	bodies	body	NOUN
fnp-3025	286	12	,	,	PUNCT
fnp-3025	286	13	which	which	PRON
fnp-3025	286	14	have	have	AUX
fnp-3025	286	15	been	be	AUX
fnp-3025	286	16	shown	show	VERB
fnp-3025	286	17	experimentally	experimentally	ADV
fnp-3025	286	18	to	to	PART
fnp-3025	286	19	be	be	AUX
fnp-3025	286	20	an	an	DET
fnp-3025	286	21	important	important	ADJ
fnp-3025	286	22	site	site	NOUN
fnp-3025	286	23	of	of	ADP
fnp-3025	286	24	app	app	PROPN
fnp-3025	286	25	/	/	SYM
fnp-3025	286	26	aβ	aβ	NOUN
fnp-3025	286	27	biology	biology	NOUN
fnp-3025	286	28	[	[	X
fnp-3025	286	29	196	196	NUM
fnp-3025	286	30	-	-	SYM
fnp-3025	286	31	201	201	NUM
fnp-3025	286	32	]	]	PUNCT
fnp-3025	286	33	.	.	PUNCT
fnp-3025	287	1	in	in	ADP
fnp-3025	287	2	this	this	DET
fnp-3025	287	3	regard	regard	NOUN
fnp-3025	287	4	,	,	PUNCT
fnp-3025	287	5	vesicular	vesicular	ADJ
fnp-3025	287	6	structures	structure	NOUN
fnp-3025	287	7	ranging	range	VERB
fnp-3025	287	8	from	from	ADP
fnp-3025	287	9	50	50	NUM
fnp-3025	287	10	to	to	PART
fnp-3025	287	11	300	300	NUM
fnp-3025	287	12	nm	nm	NOUN
fnp-3025	287	13	in	in	ADP
fnp-3025	287	14	diameter	diameter	NOUN
fnp-3025	287	15	have	have	AUX
fnp-3025	287	16	been	be	AUX
fnp-3025	287	17	reported	report	VERB
fnp-3025	287	18	among	among	ADP
fnp-3025	287	19	the	the	DET
fnp-3025	287	20	amyloid	amyloid	NOUN
fnp-3025	287	21	fibrils	fibril	NOUN
fnp-3025	287	22	in	in	ADP
fnp-3025	287	23	a	a	DET
fnp-3025	287	24	cell	cell	NOUN
fnp-3025	287	25	culture	culture	NOUN
fnp-3025	287	26	model	model	NOUN
fnp-3025	287	27	of	of	ADP
fnp-3025	287	28	aβ	aβ	DET
fnp-3025	287	29	amyloid	amyloid	NOUN
fnp-3025	287	30	deposition	deposition	NOUN
fnp-3025	288	1	[	[	X
fnp-3025	288	2	202	202	NUM
fnp-3025	288	3	]	]	PUNCT
fnp-3025	288	4	.	.	PUNCT
fnp-3025	289	1	the	the	DET
fnp-3025	289	2	center	center	NOUN
fnp-3025	289	3	of	of	ADP
fnp-3025	289	4	the	the	DET
fnp-3025	289	5	compact	compact	ADJ
fnp-3025	289	6	core	core	NOUN
fnp-3025	289	7	in	in	ADP
fnp-3025	289	8	some	some	DET
fnp-3025	289	9	aβ	aβ	NOUN
fnp-3025	289	10	-	-	PUNCT
fnp-3025	289	11	amyloid	amyloid	NOUN
fnp-3025	289	12	plaques	plaque	NOUN
fnp-3025	289	13	is	be	AUX
fnp-3025	289	14	refractory	refractory	NOUN
fnp-3025	289	15	to	to	ADP
fnp-3025	289	16	aβ	aβ	VERB
fnp-3025	289	17	-	-	PUNCT
fnp-3025	289	18	immunostaining	immunostaine	VERB
fnp-3025	289	19	(	(	PUNCT
fnp-3025	289	20	figure	figure	NOUN
fnp-3025	289	21	14	14	NUM
fnp-3025	289	22	)	)	PUNCT
fnp-3025	289	23	,	,	PUNCT
fnp-3025	289	24	even	even	ADV
fnp-3025	289	25	though	though	SCONJ
fnp-3025	289	26	it	it	PRON
fnp-3025	289	27	is	be	AUX
fnp-3025	289	28	positive	positive	ADJ
fnp-3025	289	29	for	for	ADP
fnp-3025	289	30	the	the	DET
fnp-3025	289	31	amyloid	amyloid	NOUN
fnp-3025	289	32	-	-	PUNCT
fnp-3025	289	33	selective	selective	ADJ
fnp-3025	289	34	dyes	dye	NOUN
fnp-3025	289	35	thioflavin	thioflavin	PROPN
fnp-3025	289	36	-	-	PUNCT
fnp-3025	289	37	s	s	NOUN
fnp-3025	289	38	and	and	CCONJ
fnp-3025	289	39	congo	congo	NOUN
fnp-3025	289	40	red	red	ADJ
fnp-3025	289	41	[	[	X
fnp-3025	289	42	203	203	NUM
fnp-3025	289	43	]	]	PUNCT
fnp-3025	289	44	.	.	PUNCT
fnp-3025	290	1	ultrastructural	ultrastructural	ADJ
fnp-3025	290	2	analysis	analysis	NOUN
fnp-3025	290	3	indicates	indicate	VERB
fnp-3025	290	4	that	that	SCONJ
fnp-3025	290	5	the	the	DET
fnp-3025	290	6	material	material	NOUN
fnp-3025	290	7	in	in	ADP
fnp-3025	290	8	the	the	DET
fnp-3025	290	9	center	center	NOUN
fnp-3025	290	10	of	of	ADP
fnp-3025	290	11	fully	fully	ADV
fnp-3025	290	12	developed	develop	VERB
fnp-3025	290	13	plaques	plaque	NOUN
fnp-3025	290	14	often	often	ADV
fnp-3025	290	15	has	have	VERB
fnp-3025	290	16	a	a	DET
fnp-3025	290	17	more	more	ADV
fnp-3025	290	18	granular	granular	ADJ
fnp-3025	290	19	,	,	PUNCT
fnp-3025	290	20	amorphous	amorphous	ADJ
fnp-3025	290	21	appearance	appearance	NOUN
fnp-3025	290	22	(	(	PUNCT
fnp-3025	290	23	figure	figure	NOUN
fnp-3025	290	24	13	13	NUM
fnp-3025	290	25	)	)	PUNCT
fnp-3025	290	26	than	than	ADP
fnp-3025	290	27	the	the	DET
fnp-3025	290	28	obvious	obvious	ADJ
fnp-3025	290	29	fibrils	fibril	NOUN
fnp-3025	290	30	in	in	ADP
fnp-3025	290	31	the	the	DET
fnp-3025	290	32	mantle	mantle	NOUN
fnp-3025	290	33	of	of	ADP
fnp-3025	290	34	the	the	DET
fnp-3025	290	35	core	core	NOUN
fnp-3025	290	36	and	and	CCONJ
fnp-3025	290	37	in	in	ADP
fnp-3025	290	38	the	the	DET
fnp-3025	290	39	periphery	periphery	NOUN
fnp-3025	290	40	.	.	PUNCT
fnp-3025	291	1	classical	classical	ADJ
fnp-3025	291	2	aβ	aβ	NOUN
fnp-3025	291	3	-	-	PUNCT
fnp-3025	291	4	amyloid	amyloid	NOUN
fnp-3025	291	5	plaques	plaque	NOUN
fnp-3025	291	6	are	be	AUX
fnp-3025	291	7	often	often	ADV
fnp-3025	291	8	ascribed	ascribe	VERB
fnp-3025	291	9	special	special	ADJ
fnp-3025	291	10	relevance	relevance	NOUN
fnp-3025	291	11	to	to	ADP
fnp-3025	291	12	neurodegeneration	neurodegeneration	NOUN
fnp-3025	291	13	[	[	X
fnp-3025	291	14	1	1	NUM
fnp-3025	291	15	,	,	PUNCT
fnp-3025	291	16	204	204	NUM
fnp-3025	291	17	]	]	PUNCT
fnp-3025	291	18	,	,	PUNCT
fnp-3025	291	19	as	as	SCONJ
fnp-3025	291	20	they	they	PRON
fnp-3025	291	21	are	be	AUX
fnp-3025	291	22	much	much	ADV
fnp-3025	291	23	more	more	ADV
fnp-3025	291	24	likely	likely	ADJ
fnp-3025	291	25	to	to	PART
fnp-3025	291	26	involve	involve	VERB
fnp-3025	291	27	neuritic	neuritic	ADJ
fnp-3025	291	28	malformation	malformation	NOUN
fnp-3025	291	29	and	and	CCONJ
fnp-3025	291	30	reactive	reactive	ADJ
fnp-3025	291	31	gliosis	gliosis	NOUN
fnp-3025	291	32	than	than	SCONJ
fnp-3025	291	33	are	be	AUX
fnp-3025	291	34	the	the	DET
fnp-3025	291	35	diffuse	diffuse	PROPN
fnp-3025	291	36	deposits	deposit	NOUN
fnp-3025	291	37	[	[	X
fnp-3025	291	38	133	133	NUM
fnp-3025	291	39	]	]	PUNCT
fnp-3025	291	40	.	.	PUNCT
fnp-3025	292	1	in	in	ADP
fnp-3025	292	2	this	this	DET
fnp-3025	292	3	regard	regard	NOUN
fnp-3025	292	4	,	,	PUNCT
fnp-3025	292	5	it	it	PRON
fnp-3025	292	6	is	be	AUX
fnp-3025	292	7	noteworthy	noteworthy	ADJ
fnp-3025	292	8	that	that	SCONJ
fnp-3025	292	9	cognitively	cognitively	ADV
fnp-3025	292	10	normal	normal	ADJ
fnp-3025	292	11	elderly	elderly	ADJ
fnp-3025	292	12	subjects	subject	NOUN
fnp-3025	292	13	with	with	ADP
fnp-3025	292	14	abundant	abundant	ADJ
fnp-3025	292	15	aβ	aβ	DET
fnp-3025	292	16	plaques	plaque	NOUN
fnp-3025	292	17	tend	tend	VERB
fnp-3025	292	18	to	to	PART
fnp-3025	292	19	have	have	AUX
fnp-3025	292	20	mostly	mostly	ADV
fnp-3025	292	21	diffuse	diffuse	VERB
fnp-3025	292	22	plaques	plaque	NOUN
fnp-3025	293	1	[	[	X
fnp-3025	293	2	1	1	X
fnp-3025	293	3	]	]	PUNCT
fnp-3025	293	4	with	with	ADP
fnp-3025	293	5	few	few	ADJ
fnp-3025	293	6	neurites	neurite	NOUN
fnp-3025	293	7	and	and	CCONJ
fnp-3025	293	8	little	little	ADJ
fnp-3025	293	9	glial	glial	ADJ
fnp-3025	293	10	reactivity	reactivity	NOUN
fnp-3025	293	11	[	[	X
fnp-3025	293	12	139	139	NUM
fnp-3025	293	13	]	]	PUNCT
fnp-3025	293	14	.	.	PUNCT
fnp-3025	294	1	however	however	ADV
fnp-3025	294	2	,	,	PUNCT
fnp-3025	294	3	as	as	SCONJ
fnp-3025	294	4	noted	note	VERB
fnp-3025	294	5	above	above	ADV
fnp-3025	294	6	,	,	PUNCT
fnp-3025	294	7	there	there	PRON
fnp-3025	294	8	are	be	VERB
fnp-3025	294	9	rare	rare	ADJ
fnp-3025	294	10	cases	case	NOUN
fnp-3025	294	11	of	of	ADP
fnp-3025	294	12	advanced	advanced	ADJ
fnp-3025	294	13	ad	ad	NOUN
fnp-3025	294	14	in	in	ADP
fnp-3025	294	15	which	which	PRON
fnp-3025	294	16	classical	classical	ADJ
fnp-3025	294	17	plaques	plaque	NOUN
fnp-3025	294	18	or	or	CCONJ
fnp-3025	294	19	dense	dense	ADV
fnp-3025	294	20	-	-	PUNCT
fnp-3025	294	21	cored	core	VERB
fnp-3025	294	22	plaques	plaque	NOUN
fnp-3025	294	23	are	be	AUX
fnp-3025	294	24	infrequent	infrequent	ADJ
fnp-3025	295	1	[	[	X
fnp-3025	295	2	90	90	NUM
fnp-3025	295	3	-	-	SYM
fnp-3025	295	4	93	93	NUM
fnp-3025	295	5	]	]	PUNCT
fnp-3025	295	6	,	,	PUNCT
fnp-3025	295	7	suggesting	suggest	VERB
fnp-3025	295	8	that	that	SCONJ
fnp-3025	295	9	amyloid	amyloid	NOUN
fnp-3025	295	10	per	per	X
fnp-3025	295	11	se	se	X
fnp-3025	295	12	is	be	AUX
fnp-3025	295	13	not	not	PART
fnp-3025	295	14	essential	essential	ADJ
fnp-3025	295	15	to	to	ADP
fnp-3025	295	16	the	the	DET
fnp-3025	295	17	development	development	NOUN
fnp-3025	295	18	of	of	ADP
fnp-3025	295	19	dementia	dementia	NOUN
fnp-3025	295	20	.	.	PUNCT
fnp-3025	296	1	a	a	DET
fnp-3025	296	2	similar	similar	ADJ
fnp-3025	296	3	situation	situation	NOUN
fnp-3025	296	4	holds	hold	VERB
fnp-3025	296	5	for	for	ADP
fnp-3025	296	6	prion	prion	NOUN
fnp-3025	296	7	diseases	disease	NOUN
fnp-3025	296	8	,	,	PUNCT
fnp-3025	296	9	all	all	PRON
fnp-3025	296	10	of	of	ADP
fnp-3025	296	11	which	which	PRON
fnp-3025	296	12	are	be	AUX
fnp-3025	296	13	linked	link	VERB
fnp-3025	296	14	to	to	ADP
fnp-3025	296	15	the	the	DET
fnp-3025	296	16	misfolding	misfolding	ADJ
fnp-3025	296	17	and	and	CCONJ
fnp-3025	296	18	self	self	NOUN
fnp-3025	296	19	-	-	PUNCT
fnp-3025	296	20	assembly	assembly	NOUN
fnp-3025	296	21	of	of	ADP
fnp-3025	296	22	prp	prp	NOUN
fnp-3025	297	1	[	[	X
fnp-3025	297	2	205	205	NUM
fnp-3025	297	3	,	,	PUNCT
fnp-3025	297	4	206	206	NUM
fnp-3025	297	5	]	]	PUNCT
fnp-3025	297	6	;	;	PUNCT
fnp-3025	297	7	in	in	ADP
fnp-3025	297	8	some	some	DET
fnp-3025	297	9	prionoses	prionose	NOUN
fnp-3025	297	10	(	(	PUNCT
fnp-3025	297	11	such	such	ADJ
fnp-3025	297	12	as	as	ADP
fnp-3025	297	13	gerstmann	gerstmann	NOUN
fnp-3025	297	14	-	-	PUNCT
fnp-3025	297	15	sträussler	sträussler	NOUN
fnp-3025	297	16	-	-	PUNCT
fnp-3025	297	17	scheinker	scheinker	NOUN
fnp-3025	297	18	syndrome	syndrome	NOUN
fnp-3025	297	19	and	and	CCONJ
fnp-3025	297	20	new	new	ADJ
fnp-3025	297	21	-	-	PUNCT
fnp-3025	297	22	variant	variant	NOUN
fnp-3025	297	23	creutzfeldt	creutzfeldt	ADJ
fnp-3025	297	24	-	-	PUNCT
fnp-3025	297	25	jakob	jakob	ADJ
fnp-3025	297	26	disease	disease	NOUN
fnp-3025	297	27	)	)	PUNCT
fnp-3025	297	28	,	,	PUNCT
fnp-3025	297	29	prp	prp	NOUN
fnp-3025	297	30	-	-	PUNCT
fnp-3025	297	31	amyloid	amyloid	NOUN
fnp-3025	297	32	plaques	plaque	NOUN
fnp-3025	297	33	can	can	AUX
fnp-3025	297	34	be	be	AUX
fnp-3025	297	35	numerous	numerous	ADJ
fnp-3025	297	36	,	,	PUNCT
fnp-3025	297	37	whereas	whereas	SCONJ
fnp-3025	297	38	in	in	ADP
fnp-3025	297	39	others	other	NOUN
fnp-3025	297	40	,	,	PUNCT
fnp-3025	297	41	little	little	ADJ
fnp-3025	297	42	if	if	SCONJ
fnp-3025	297	43	any	any	DET
fnp-3025	297	44	amyloid	amyloid	NOUN
fnp-3025	297	45	is	be	AUX
fnp-3025	297	46	present	present	ADJ
fnp-3025	298	1	[	[	X
fnp-3025	298	2	127	127	NUM
fnp-3025	298	3	]	]	PUNCT
fnp-3025	298	4	.	.	PUNCT
fnp-3025	299	1	in	in	ADP
fnp-3025	299	2	these	these	DET
fnp-3025	299	3	instances	instance	NOUN
fnp-3025	299	4	,	,	PUNCT
fnp-3025	299	5	oligomeric	oligomeric	ADJ
fnp-3025	299	6	species	specie	NOUN
fnp-3025	299	7	of	of	ADP
fnp-3025	299	8	the	the	DET
fnp-3025	299	9	proteins	protein	NOUN
fnp-3025	299	10	may	may	AUX
fnp-3025	299	11	have	have	VERB
fnp-3025	299	12	particular	particular	ADJ
fnp-3025	299	13	importance	importance	NOUN
fnp-3025	299	14	[	[	X
fnp-3025	299	15	20	20	NUM
fnp-3025	299	16	]	]	PUNCT
fnp-3025	299	17	,	,	PUNCT
fnp-3025	299	18	although	although	SCONJ
fnp-3025	299	19	this	this	PRON
fnp-3025	299	20	has	have	AUX
fnp-3025	299	21	not	not	PART
fnp-3025	299	22	been	be	AUX
fnp-3025	299	23	definitely	definitely	ADV
fnp-3025	299	24	established	establish	VERB
fnp-3025	299	25	.	.	PUNCT
fnp-3025	300	1	figure	figure	NOUN
fnp-3025	300	2	12	12	NUM
fnp-3025	300	3	.	.	PUNCT
fnp-3025	301	1	ultrastructure	ultrastructure	NOUN
fnp-3025	301	2	of	of	ADP
fnp-3025	301	3	fibrillar	fibrillar	ADJ
fnp-3025	301	4	aβ	aβ	NOUN
fnp-3025	301	5	in	in	ADP
fnp-3025	301	6	the	the	DET
fnp-3025	301	7	plaque	plaque	NOUN
fnp-3025	301	8	corona	corona	NOUN
fnp-3025	301	9	(	(	PUNCT
fnp-3025	301	10	left	left	ADJ
fnp-3025	301	11	)	)	PUNCT
fnp-3025	301	12	and	and	CCONJ
fnp-3025	301	13	core	core	NOUN
fnp-3025	301	14	(	(	PUNCT
fnp-3025	301	15	right	right	ADJ
fnp-3025	301	16	)	)	PUNCT
fnp-3025	301	17	in	in	ADP
fnp-3025	301	18	an	an	DET
fnp-3025	301	19	ad	ad	NOUN
fnp-3025	301	20	patient	patient	NOUN
fnp-3025	301	21	.	.	PUNCT
fnp-3025	302	1	bar	bar	NOUN
fnp-3025	302	2	=	=	PUNCT
fnp-3025	302	3	500	500	NUM
fnp-3025	302	4	nm	nm	NOUN
fnp-3025	302	5	for	for	ADP
fnp-3025	302	6	both	both	DET
fnp-3025	302	7	images	image	NOUN
fnp-3025	302	8	.	.	PUNCT
fnp-3025	303	1	a	a	DET
fnp-3025	303	2	small	small	ADJ
fnp-3025	303	3	proportion	proportion	NOUN
fnp-3025	303	4	of	of	ADP
fnp-3025	303	5	aβ	aβ	NOUN
fnp-3025	303	6	-	-	PUNCT
fnp-3025	303	7	amyloid	amyloid	NOUN
fnp-3025	303	8	plaques	plaque	NOUN
fnp-3025	303	9	lack	lack	VERB
fnp-3025	303	10	the	the	DET
fnp-3025	303	11	outer	outer	ADJ
fnp-3025	303	12	corona	corona	NOUN
fnp-3025	303	13	and	and	CCONJ
fnp-3025	303	14	have	have	VERB
fnp-3025	303	15	few	few	ADJ
fnp-3025	303	16	or	or	CCONJ
fnp-3025	303	17	no	no	PRON
fnp-3025	303	18	neurites	neurite	NOUN
fnp-3025	303	19	;	;	PUNCT
fnp-3025	303	20	these	these	DET
fnp-3025	303	21	relatively	relatively	ADV
fnp-3025	303	22	plain	plain	ADJ
fnp-3025	303	23	structures	structure	NOUN
fnp-3025	303	24	have	have	AUX
fnp-3025	303	25	been	be	AUX
fnp-3025	303	26	thought	think	VERB
fnp-3025	303	27	to	to	PART
fnp-3025	303	28	represent	represent	VERB
fnp-3025	303	29	an	an	DET
fnp-3025	303	30	end	end	NOUN
fnp-3025	303	31	-	-	PUNCT
fnp-3025	303	32	stage	stage	NOUN
fnp-3025	303	33	in	in	ADP
fnp-3025	303	34	the	the	DET
fnp-3025	303	35	evolution	evolution	NOUN
fnp-3025	303	36	of	of	ADP
fnp-3025	303	37	plaques	plaque	NOUN
fnp-3025	303	38	,	,	PUNCT
fnp-3025	303	39	and	and	CCONJ
fnp-3025	303	40	so	so	ADV
fnp-3025	303	41	were	be	AUX
fnp-3025	303	42	dubbed	dub	VERB
fnp-3025	303	43	‘	'	PUNCT
fnp-3025	303	44	burned	burn	VERB
fnp-3025	303	45	out	out	ADP
fnp-3025	303	46	’	'	PUNCT
fnp-3025	303	47	plaques	plaque	NOUN
fnp-3025	303	48	[	[	X
fnp-3025	303	49	143	143	NUM
fnp-3025	303	50	,	,	PUNCT
fnp-3025	303	51	178	178	NUM
fnp-3025	303	52	]	]	PUNCT
fnp-3025	303	53	.	.	PUNCT
fnp-3025	304	1	based	base	VERB
fnp-3025	304	2	on	on	ADP
fnp-3025	304	3	their	their	PRON
fnp-3025	304	4	apparent	apparent	ADJ
fnp-3025	304	5	sequential	sequential	ADJ
fnp-3025	304	6	appearance	appearance	NOUN
fnp-3025	304	7	ance	ance	NOUN
fnp-3025	304	8	in	in	ADP
fnp-3025	304	9	the	the	DET
fnp-3025	304	10	ad	ad	NOUN
fnp-3025	304	11	brain	brain	NOUN
fnp-3025	304	12	,	,	PUNCT
fnp-3025	304	13	a	a	DET
fnp-3025	304	14	progression	progression	NOUN
fnp-3025	304	15	has	have	AUX
fnp-3025	304	16	been	be	AUX
fnp-3025	304	17	proposed	propose	VERB
fnp-3025	304	18	in	in	ADP
fnp-3025	304	19	which	which	PRON
fnp-3025	304	20	plaques	plaque	NOUN
fnp-3025	304	21	originate	originate	VERB
fnp-3025	304	22	as	as	ADP
fnp-3025	304	23	diffuse	diffuse	ADJ
fnp-3025	304	24	(	(	PUNCT
fnp-3025	304	25	‘	'	PUNCT
fnp-3025	304	26	primitive	primitive	ADJ
fnp-3025	304	27	’	'	PUNCT
fnp-3025	304	28	or	or	CCONJ
fnp-3025	304	29	‘	'	PUNCT
fnp-3025	304	30	immature	immature	ADJ
fnp-3025	304	31	’	'	PUNCT
fnp-3025	304	32	)	)	PUNCT
fnp-3025	304	33	deposits	deposit	NOUN
fnp-3025	304	34	that	that	PRON
fnp-3025	304	35	evolve	evolve	VERB
fnp-3025	304	36	into	into	ADP
fnp-3025	304	37	classical	classical	ADJ
fnp-3025	304	38	(	(	PUNCT
fnp-3025	304	39	or	or	CCONJ
fnp-3025	304	40	‘	'	PUNCT
fnp-3025	304	41	mature	mature	ADJ
fnp-3025	304	42	’	'	PUNCT
fnp-3025	304	43	)	)	PUNCT
fnp-3025	305	1	aβ	aβ	ADP
fnp-3025	305	2	plaques	plaque	NOUN
fnp-3025	305	3	and	and	CCONJ
fnp-3025	305	4	then	then	ADV
fnp-3025	305	5	finally	finally	ADV
fnp-3025	305	6	into	into	ADP
fnp-3025	305	7	burned	burn	VERB
fnp-3025	305	8	-	-	PUNCT
fnp-3025	305	9	out	out	ADP
fnp-3025	305	10	plaques	plaque	NOUN
fnp-3025	306	1	[	[	X
fnp-3025	306	2	143].11	143].11	NUM
fnp-3025	306	3	while	while	SCONJ
fnp-3025	306	4	longitudinal	longitudinal	ADJ
fnp-3025	306	5	studies	study	NOUN
fnp-3025	306	6	in	in	ADP
fnp-3025	306	7	mouse	mouse	NOUN
fnp-3025	306	8	models	model	NOUN
fnp-3025	306	9	of	of	ADP
fnp-3025	306	10	cerebral	cerebral	ADJ
fnp-3025	306	11	aβ	aβ	NOUN
fnp-3025	306	12	accumulation	accumulation	NOUN
fnp-3025	306	13	have	have	AUX
fnp-3025	306	14	begun	begin	VERB
fnp-3025	306	15	to	to	PART
fnp-3025	306	16	shed	shed	VERB
fnp-3025	306	17	light	light	NOUN
fnp-3025	306	18	on	on	ADP
fnp-3025	306	19	the	the	DET
fnp-3025	306	20	time	time	NOUN
fnp-3025	306	21	-	-	PUNCT
fnp-3025	306	22	course	course	NOUN
fnp-3025	306	23	of	of	ADP
fnp-3025	306	24	plaque	plaque	NOUN
fnp-3025	306	25	development	development	NOUN
fnp-3025	306	26	(	(	PUNCT
fnp-3025	306	27	see	see	VERB
fnp-3025	306	28	section	section	NOUN
fnp-3025	306	29	10.2	10.2	NUM
fnp-3025	306	30	)	)	PUNCT
fnp-3025	306	31	,	,	PUNCT
fnp-3025	306	32	the	the	DET
fnp-3025	306	33	order	order	NOUN
fnp-3025	306	34	of	of	ADP
fnp-3025	306	35	events	event	NOUN
fnp-3025	306	36	in	in	ADP
fnp-3025	306	37	the	the	DET
fnp-3025	306	38	human	human	ADJ
fnp-3025	306	39	brain	brain	NOUN
fnp-3025	306	40	is	be	AUX
fnp-3025	306	41	still	still	ADV
fnp-3025	306	42	speculative	speculative	ADJ
fnp-3025	306	43	[	[	X
fnp-3025	306	44	207	207	NUM
fnp-3025	306	45	]	]	PUNCT
fnp-3025	306	46	.	.	PUNCT
fnp-3025	307	1	figure	figure	NOUN
fnp-3025	307	2	13	13	NUM
fnp-3025	307	3	.	.	PUNCT
fnp-3025	308	1	high	high	ADJ
fnp-3025	308	2	-	-	PUNCT
fnp-3025	308	3	magnification	magnification	NOUN
fnp-3025	308	4	electron	electron	NOUN
fnp-3025	308	5	micrograph	micrograph	NOUN
fnp-3025	308	6	of	of	ADP
fnp-3025	308	7	a	a	DET
fnp-3025	308	8	portion	portion	NOUN
fnp-3025	308	9	of	of	ADP
fnp-3025	308	10	the	the	DET
fnp-3025	308	11	core	core	NOUN
fnp-3025	308	12	of	of	ADP
fnp-3025	308	13	an	an	DET
fnp-3025	308	14	aβ	aβ	NOUN
fnp-3025	308	15	-	-	PUNCT
fnp-3025	308	16	amyloid	amyloid	NOUN
fnp-3025	308	17	plaque	plaque	NOUN
fnp-3025	308	18	in	in	ADP
fnp-3025	308	19	an	an	DET
fnp-3025	308	20	ad	ad	NOUN
fnp-3025	308	21	patient	patient	NOUN
fnp-3025	308	22	.	.	PUNCT
fnp-3025	309	1	the	the	DET
fnp-3025	309	2	fibrillarity	fibrillarity	NOUN
fnp-3025	309	3	of	of	ADP
fnp-3025	309	4	the	the	DET
fnp-3025	309	5	material	material	NOUN
fnp-3025	309	6	is	be	AUX
fnp-3025	309	7	less	less	ADV
fnp-3025	309	8	evident	evident	ADJ
fnp-3025	309	9	than	than	ADP
fnp-3025	309	10	in	in	ADP
fnp-3025	309	11	more	more	ADJ
fnp-3025	309	12	peripheral	peripheral	ADJ
fnp-3025	309	13	zones	zone	NOUN
fnp-3025	309	14	.	.	PUNCT
fnp-3025	310	1	unidentified	unidentified	ADJ
fnp-3025	310	2	particles	particle	NOUN
fnp-3025	310	3	(	(	PUNCT
fnp-3025	310	4	2	2	NUM
fnp-3025	310	5	are	be	AUX
fnp-3025	310	6	marked	mark	VERB
fnp-3025	310	7	by	by	ADP
fnp-3025	310	8	arrows	arrow	NOUN
fnp-3025	310	9	)	)	PUNCT
fnp-3025	310	10	of	of	ADP
fnp-3025	310	11	various	various	ADJ
fnp-3025	310	12	sizes	size	NOUN
fnp-3025	310	13	and	and	CCONJ
fnp-3025	310	14	densities	density	NOUN
fnp-3025	310	15	are	be	AUX
fnp-3025	310	16	interspersed	intersperse	VERB
fnp-3025	310	17	among	among	ADP
fnp-3025	310	18	the	the	DET
fnp-3025	310	19	amyloid	amyloid	NOUN
fnp-3025	310	20	fibrils	fibril	NOUN
fnp-3025	310	21	;	;	PUNCT
fnp-3025	310	22	these	these	PRON
fnp-3025	310	23	can	can	AUX
fnp-3025	310	24	be	be	AUX
fnp-3025	310	25	found	find	VERB
fnp-3025	310	26	both	both	PRON
fnp-3025	310	27	in	in	ADP
fnp-3025	310	28	the	the	DET
fnp-3025	310	29	core	core	NOUN
fnp-3025	310	30	and	and	CCONJ
fnp-3025	310	31	corona	corona	NOUN
fnp-3025	310	32	.	.	PUNCT
fnp-3025	311	1	bar	bar	NOUN
fnp-3025	311	2	=	=	PUNCT
fnp-3025	311	3	200	200	NUM
fnp-3025	311	4	nm	nm	NOUN
fnp-3025	311	5	.	.	PUNCT
fnp-3025	312	1	figure	figure	NOUN
fnp-3025	312	2	14	14	NUM
fnp-3025	312	3	.	.	PUNCT
fnp-3025	313	1	aβ	aβ	PRON
fnp-3025	313	2	plaque	plaque	NOUN
fnp-3025	313	3	with	with	ADP
fnp-3025	313	4	an	an	DET
fnp-3025	313	5	antibody	antibody	NOUN
fnp-3025	313	6	-	-	PUNCT
fnp-3025	313	7	refractory	refractory	NOUN
fnp-3025	313	8	central	central	ADJ
fnp-3025	313	9	core	core	NOUN
fnp-3025	313	10	in	in	ADP
fnp-3025	313	11	an	an	DET
fnp-3025	313	12	ad	ad	NOUN
fnp-3025	313	13	patient	patient	NOUN
fnp-3025	313	14	.	.	PUNCT
fnp-3025	314	1	antibody	antibody	NOUN
fnp-3025	314	2	6e10	6e10	NOUN
fnp-3025	314	3	;	;	PUNCT
fnp-3025	314	4	nissl	nissl	ADJ
fnp-3025	314	5	counterstain	counterstain	NOUN
fnp-3025	314	6	.	.	PUNCT
fnp-3025	315	1	bar	bar	NOUN
fnp-3025	315	2	=	=	SYM
fnp-3025	315	3	20μm	20μm	NOUN
fnp-3025	315	4	.	.	PUNCT
fnp-3025	316	1	biochemical	biochemical	ADJ
fnp-3025	316	2	determination	determination	NOUN
fnp-3025	316	3	of	of	ADP
fnp-3025	316	4	the	the	DET
fnp-3025	316	5	age	age	NOUN
fnp-3025	316	6	of	of	ADP
fnp-3025	316	7	aβ	aβ	PRON
fnp-3025	316	8	deposits	deposit	NOUN
fnp-3025	316	9	indicates	indicate	VERB
fnp-3025	316	10	that	that	SCONJ
fnp-3025	316	11	the	the	DET
fnp-3025	316	12	amyloid	amyloid	NOUN
fnp-3025	316	13	core	core	NOUN
fnp-3025	316	14	is	be	AUX
fnp-3025	316	15	older	old	ADJ
fnp-3025	316	16	than	than	ADP
fnp-3025	316	17	the	the	DET
fnp-3025	316	18	diffuse	diffuse	NOUN
fnp-3025	316	19	aβ	aβ	NOUN
fnp-3025	316	20	in	in	ADP
fnp-3025	316	21	the	the	DET
fnp-3025	316	22	corona	corona	NOUN
fnp-3025	316	23	and	and	CCONJ
fnp-3025	316	24	in	in	ADP
fnp-3025	316	25	diffuse	diffuse	ADJ
fnp-3025	316	26	plaques	plaque	NOUN
fnp-3025	316	27	[	[	X
fnp-3025	316	28	208	208	NUM
fnp-3025	316	29	,	,	PUNCT
fnp-3025	316	30	209	209	NUM
fnp-3025	316	31	]	]	PUNCT
fnp-3025	316	32	.	.	PUNCT
fnp-3025	317	1	armstrong	armstrong	PROPN
fnp-3025	318	1	[	[	X
fnp-3025	318	2	173	173	NUM
fnp-3025	318	3	]	]	PUNCT
fnp-3025	318	4	has	have	AUX
fnp-3025	318	5	suggested	suggest	VERB
fnp-3025	318	6	that	that	SCONJ
fnp-3025	318	7	the	the	DET
fnp-3025	318	8	major	major	ADJ
fnp-3025	318	9	plaque	plaque	NOUN
fnp-3025	318	10	types	type	NOUN
fnp-3025	318	11	mostly	mostly	ADV
fnp-3025	318	12	arise	arise	VERB
fnp-3025	318	13	independently	independently	ADV
fnp-3025	318	14	,	,	PUNCT
fnp-3025	318	15	rather	rather	ADV
fnp-3025	318	16	than	than	ADP
fnp-3025	318	17	in	in	ADP
fnp-3025	318	18	an	an	DET
fnp-3025	318	19	evolutionary	evolutionary	ADJ
fnp-3025	318	20	progression	progression	NOUN
fnp-3025	318	21	.	.	PUNCT
fnp-3025	319	1	in	in	ADP
fnp-3025	319	2	any	any	DET
fnp-3025	319	3	case	case	NOUN
fnp-3025	319	4	,	,	PUNCT
fnp-3025	319	5	the	the	DET
fnp-3025	319	6	transformation	transformation	NOUN
fnp-3025	319	7	of	of	ADP
fnp-3025	319	8	diffuse	diffuse	ADJ
fnp-3025	319	9	plaques	plaque	NOUN
fnp-3025	319	10	into	into	ADP
fnp-3025	319	11	compact	compact	ADJ
fnp-3025	319	12	amyloid	amyloid	NOUN
fnp-3025	319	13	might	might	AUX
fnp-3025	319	14	not	not	PART
fnp-3025	319	15	be	be	AUX
fnp-3025	319	16	an	an	DET
fnp-3025	319	17	inevitable	inevitable	ADJ
fnp-3025	319	18	occurrence	occurrence	NOUN
fnp-3025	319	19	;	;	PUNCT
fnp-3025	319	20	for	for	ADP
fnp-3025	319	21	instance	instance	NOUN
fnp-3025	319	22	,	,	PUNCT
fnp-3025	319	23	it	it	PRON
fnp-3025	319	24	appears	appear	VERB
fnp-3025	319	25	that	that	SCONJ
fnp-3025	319	26	diffuse	diffuse	VERB
fnp-3025	319	27	aβ	aβ	ADP
fnp-3025	319	28	deposits	deposit	NOUN
fnp-3025	319	29	such	such	ADJ
fnp-3025	319	30	as	as	ADP
fnp-3025	319	31	the	the	DET
fnp-3025	319	32	lake	lake	NOUN
fnp-3025	319	33	-	-	PUNCT
fnp-3025	319	34	like	like	ADJ
fnp-3025	319	35	cloud	cloud	NOUN
fnp-3025	319	36	of	of	ADP
fnp-3025	319	37	aβ	aβ	PRON
fnp-3025	319	38	in	in	ADP
fnp-3025	319	39	the	the	DET
fnp-3025	319	40	subicular	subicular	ADJ
fnp-3025	319	41	complex	complex	NOUN
fnp-3025	319	42	(	(	PUNCT
fnp-3025	319	43	figure	figure	NOUN
fnp-3025	319	44	9	9	NUM
fnp-3025	319	45	)	)	PUNCT
fnp-3025	319	46	do	do	AUX
fnp-3025	319	47	not	not	PART
fnp-3025	319	48	progress	progress	VERB
fnp-3025	319	49	into	into	ADP
fnp-3025	319	50	dense	dense	ADJ
fnp-3025	319	51	masses	masse	NOUN
fnp-3025	319	52	of	of	ADP
fnp-3025	319	53	amyloid	amyloid	NOUN
fnp-3025	319	54	,	,	PUNCT
fnp-3025	319	55	and	and	CCONJ
fnp-3025	319	56	this	this	PRON
fnp-3025	319	57	may	may	AUX
fnp-3025	319	58	be	be	AUX
fnp-3025	319	59	true	true	ADJ
fnp-3025	319	60	also	also	ADV
fnp-3025	319	61	for	for	ADP
fnp-3025	319	62	cotton	cotton	NOUN
fnp-3025	319	63	-	-	PUNCT
fnp-3025	319	64	wool	wool	NOUN
fnp-3025	319	65	plaques	plaque	NOUN
fnp-3025	319	66	in	in	ADP
fnp-3025	319	67	ad	ad	NOUN
fnp-3025	319	68	cases	case	NOUN
fnp-3025	319	69	with	with	ADP
fnp-3025	319	70	certain	certain	ADJ
fnp-3025	319	71	presenilin-1	presenilin-1	NUM
fnp-3025	319	72	mutations	mutation	NOUN
fnp-3025	319	73	[	[	X
fnp-3025	319	74	90	90	NUM
fnp-3025	319	75	,	,	PUNCT
fnp-3025	319	76	91	91	NUM
fnp-3025	319	77	,	,	PUNCT
fnp-3025	319	78	93	93	NUM
fnp-3025	319	79	]	]	PUNCT
fnp-3025	319	80	.	.	PUNCT
fnp-3025	320	1	finally	finally	ADV
fnp-3025	320	2	,	,	PUNCT
fnp-3025	320	3	it	it	PRON
fnp-3025	320	4	should	should	AUX
fnp-3025	320	5	be	be	AUX
fnp-3025	320	6	emphasized	emphasize	VERB
fnp-3025	320	7	that	that	SCONJ
fnp-3025	320	8	the	the	DET
fnp-3025	320	9	relative	relative	ADJ
fnp-3025	320	10	pathogenicity	pathogenicity	NOUN
fnp-3025	320	11	of	of	ADP
fnp-3025	320	12	the	the	DET
fnp-3025	320	13	many	many	ADJ
fnp-3025	320	14	different	different	ADJ
fnp-3025	320	15	aβ	aβ	NOUN
fnp-3025	320	16	plaque	plaque	NOUN
fnp-3025	320	17	types	type	NOUN
fnp-3025	320	18	in	in	ADP
fnp-3025	320	19	the	the	DET
fnp-3025	320	20	aging	age	VERB
fnp-3025	320	21	human	human	ADJ
fnp-3025	320	22	brain	brain	NOUN
fnp-3025	320	23	remains	remain	VERB
fnp-3025	320	24	ambiguous	ambiguous	ADJ
fnp-3025	320	25	.	.	PUNCT
fnp-3025	321	1	it	it	PRON
fnp-3025	321	2	is	be	AUX
fnp-3025	321	3	fairly	fairly	ADV
fnp-3025	321	4	certain	certain	ADJ
fnp-3025	321	5	that	that	SCONJ
fnp-3025	321	6	reactive	reactive	ADJ
fnp-3025	321	7	gliosis	gliosis	NOUN
fnp-3025	321	8	/	/	SYM
fnp-3025	321	9	inflammation	inflammation	NOUN
fnp-3025	321	10	and	and	CCONJ
fnp-3025	321	11	the	the	DET
fnp-3025	321	12	local	local	ADJ
fnp-3025	321	13	disruption	disruption	NOUN
fnp-3025	321	14	of	of	ADP
fnp-3025	321	15	neuronal	neuronal	ADJ
fnp-3025	321	16	processes	process	NOUN
fnp-3025	321	17	in	in	ADP
fnp-3025	321	18	classical	classical	ADJ
fnp-3025	321	19	aβ	aβ	NOUN
fnp-3025	321	20	plaques	plaque	NOUN
fnp-3025	321	21	are	be	AUX
fnp-3025	321	22	deleterious	deleterious	ADJ
fnp-3025	321	23	to	to	ADP
fnp-3025	321	24	brain	brain	NOUN
fnp-3025	321	25	function	function	NOUN
fnp-3025	321	26	(	(	PUNCT
fnp-3025	321	27	see	see	VERB
fnp-3025	321	28	section	section	NOUN
fnp-3025	321	29	6	6	NUM
fnp-3025	321	30	)	)	PUNCT
fnp-3025	321	31	,	,	PUNCT
fnp-3025	321	32	but	but	CCONJ
fnp-3025	321	33	it	it	PRON
fnp-3025	321	34	is	be	AUX
fnp-3025	321	35	likely	likely	ADJ
fnp-3025	321	36	that	that	SCONJ
fnp-3025	321	37	oligomeric	oligomeric	ADJ
fnp-3025	321	38	agents	agent	NOUN
fnp-3025	321	39	are	be	AUX
fnp-3025	321	40	the	the	DET
fnp-3025	321	41	more	more	ADV
fnp-3025	321	42	directly	directly	ADV
fnp-3025	321	43	injurious	injurious	ADJ
fnp-3025	321	44	manifestation	manifestation	NOUN
fnp-3025	321	45	of	of	ADP
fnp-3025	321	46	misfolded	misfolded	ADJ
fnp-3025	321	47	proteins	protein	NOUN
fnp-3025	321	48	(	(	PUNCT
fnp-3025	321	49	see	see	VERB
fnp-3025	321	50	section	section	NOUN
fnp-3025	321	51	1.1	1.1	NUM
fnp-3025	321	52	)	)	PUNCT
fnp-3025	321	53	.	.	PUNCT
fnp-3025	322	1	in	in	ADP
fnp-3025	322	2	fact	fact	NOUN
fnp-3025	322	3	,	,	PUNCT
fnp-3025	322	4	while	while	SCONJ
fnp-3025	322	5	the	the	DET
fnp-3025	322	6	plaques	plaque	NOUN
fnp-3025	322	7	themselves	themselves	PRON
fnp-3025	322	8	are	be	AUX
fnp-3025	322	9	indicative	indicative	ADJ
fnp-3025	322	10	of	of	ADP
fnp-3025	322	11	a	a	DET
fnp-3025	322	12	pathogenic	pathogenic	ADJ
fnp-3025	322	13	molecular	molecular	ADJ
fnp-3025	322	14	process	process	NOUN
fnp-3025	322	15	,	,	PUNCT
fnp-3025	322	16	in	in	ADP
fnp-3025	322	17	and	and	CCONJ
fnp-3025	322	18	of	of	ADP
fnp-3025	322	19	themselves	themselves	PRON
fnp-3025	322	20	they	they	PRON
fnp-3025	322	21	may	may	AUX
fnp-3025	322	22	be	be	AUX
fnp-3025	322	23	relatively	relatively	ADV
fnp-3025	322	24	benign	benign	ADJ
fnp-3025	322	25	or	or	CCONJ
fnp-3025	322	26	even	even	ADV
fnp-3025	322	27	protective	protective	ADJ
fnp-3025	322	28	[	[	NOUN
fnp-3025	322	29	210	210	NUM
fnp-3025	322	30	,	,	PUNCT
fnp-3025	322	31	211	211	NUM
fnp-3025	322	32	]	]	PUNCT
fnp-3025	322	33	,	,	PUNCT
fnp-3025	322	34	at	at	ADP
fnp-3025	322	35	least	least	ADJ
fnp-3025	322	36	when	when	SCONJ
fnp-3025	322	37	inflammation	inflammation	NOUN
fnp-3025	322	38	and	and	CCONJ
fnp-3025	322	39	surrounding	surround	VERB
fnp-3025	322	40	oligomers	oligomer	NOUN
fnp-3025	322	41	are	be	AUX
fnp-3025	322	42	negligible	negligible	ADJ
fnp-3025	322	43	(	(	PUNCT
fnp-3025	322	44	see	see	VERB
fnp-3025	322	45	sections	section	NOUN
fnp-3025	322	46	1.1	1.1	NUM
fnp-3025	322	47	and	and	CCONJ
fnp-3025	322	48	6	6	NUM
fnp-3025	322	49	)	)	PUNCT
fnp-3025	322	50	.	.	PUNCT
fnp-3025	323	1	10	10	NUM
fnp-3025	323	2	fischer	fischer	NOUN
fnp-3025	323	3	[	[	X
fnp-3025	323	4	1910	1910	NUM
fnp-3025	323	5	]	]	PUNCT
fnp-3025	324	1	[	[	X
fnp-3025	324	2	reference	reference	NOUN
fnp-3025	324	3	185	185	NUM
fnp-3025	324	4	]	]	PUNCT
fnp-3025	324	5	referred	refer	VERB
fnp-3025	324	6	to	to	ADP
fnp-3025	324	7	the	the	DET
fnp-3025	324	8	central	central	ADJ
fnp-3025	324	9	core	core	NOUN
fnp-3025	324	10	as	as	ADP
fnp-3025	324	11	the	the	DET
fnp-3025	324	12	‘	'	PUNCT
fnp-3025	324	13	morgenstern	morgenstern	ADJ
fnp-3025	324	14	’	'	PUNCT
fnp-3025	324	15	(	(	PUNCT
fnp-3025	324	16	morning	morning	NOUN
fnp-3025	324	17	star	star	PROPN
fnp-3025	324	18	)	)	PUNCT
fnp-3025	324	19	,	,	PUNCT
fnp-3025	324	20	and	and	CCONJ
fnp-3025	324	21	described	describe	VERB
fnp-3025	324	22	the	the	DET
fnp-3025	324	23	structure	structure	NOUN
fnp-3025	324	24	of	of	ADP
fnp-3025	324	25	one	one	NUM
fnp-3025	324	26	type	type	NOUN
fnp-3025	324	27	of	of	ADP
fnp-3025	324	28	plaque	plaque	NOUN
fnp-3025	324	29	thusly	thusly	ADV
fnp-3025	324	30	:	:	PUNCT
fnp-3025	324	31	‘	'	PUNCT
fnp-3025	324	32	auch	auch	ADJ
fnp-3025	324	33	hier	hier	NOUN
fnp-3025	324	34	ist	ist	NOUN
fnp-3025	324	35	ein	ein	PROPN
fnp-3025	324	36	zentraler	zentraler	PROPN
fnp-3025	324	37	morgenstern	morgenstern	PROPN
fnp-3025	324	38	,	,	PUNCT
fnp-3025	324	39	aus	aus	PROPN
fnp-3025	324	40	dem	dem	PROPN
fnp-3025	324	41	mehr	mehr	NOUN
fnp-3025	324	42	oder	oder	NOUN
fnp-3025	324	43	weniger	weniger	NOUN
fnp-3025	324	44	lange	lange	PROPN
fnp-3025	324	45	büschel	büschel	PROPN
fnp-3025	324	46	entspringen	entspringen	PROPN
fnp-3025	324	47	;	;	PUNCT
fnp-3025	324	48	der	der	ADJ
fnp-3025	324	49	fädchenring	fädchenre	VERB
fnp-3025	324	50	ist	ist	NOUN
fnp-3025	324	51	ziemlich	ziemlich	PROPN
fnp-3025	324	52	weit	weit	PROPN
fnp-3025	324	53	vom	vom	PROPN
fnp-3025	324	54	zentrum	zentrum	PROPN
fnp-3025	324	55	entfernt	entfernt	PROPN
fnp-3025	324	56	,	,	PUNCT
fnp-3025	324	57	so	so	ADV
fnp-3025	324	58	dass	dass	PROPN
fnp-3025	324	59	ein	ein	PROPN
fnp-3025	324	60	grosser	gross	ADJ
fnp-3025	324	61	hof	hof	PROPN
fnp-3025	324	62	entsteht	entsteht	PROPN
fnp-3025	324	63	,	,	PUNCT
fnp-3025	324	64	der	der	PROPN
fnp-3025	324	65	von	von	PROPN
fnp-3025	324	66	den	den	PROPN
fnp-3025	324	67	strähnchen	strähnchen	PROPN
fnp-3025	324	68	durchzogen	durchzogen	PROPN
fnp-3025	324	69	wird	wird	PROPN
fnp-3025	324	70	’	'	PUNCT
fnp-3025	324	71	11	11	NUM
fnp-3025	324	72	diffuse	diffuse	NOUN
fnp-3025	324	73	plaques	plaque	NOUN
fnp-3025	324	74	have	have	AUX
fnp-3025	324	75	long	long	ADV
fnp-3025	324	76	been	be	AUX
fnp-3025	324	77	considered	consider	VERB
fnp-3025	324	78	an	an	DET
fnp-3025	324	79	early	early	ADJ
fnp-3025	324	80	stage	stage	NOUN
fnp-3025	324	81	in	in	ADP
fnp-3025	324	82	plaque	plaque	NOUN
fnp-3025	324	83	formation	formation	NOUN
fnp-3025	324	84	(	(	PUNCT
fnp-3025	324	85	see	see	VERB
fnp-3025	324	86	,	,	PUNCT
fnp-3025	324	87	e.g.	e.g.	ADV
fnp-3025	324	88	,	,	PUNCT
fnp-3025	324	89	critchley	critchley	NOUN
fnp-3025	324	90	[	[	X
fnp-3025	324	91	1929	1929	NUM
fnp-3025	324	92	]	]	PUNCT
fnp-3025	325	1	[	[	X
fnp-3025	325	2	reference	reference	NOUN
fnp-3025	325	3	116	116	NUM
fnp-3025	325	4	]	]	PUNCT
fnp-3025	325	5	)	)	PUNCT
fnp-3025	325	6	.	.	PUNCT
fnp-3025	326	1	5.2	5.2	NUM
fnp-3025	326	2	aβ	aβ	NOUN
fnp-3025	326	3	strains	strain	NOUN
fnp-3025	326	4	in	in	ADP
fnp-3025	326	5	ad	ad	NOUN
fnp-3025	326	6	,	,	PUNCT
fnp-3025	326	7	the	the	DET
fnp-3025	326	8	diverse	diverse	ADJ
fnp-3025	326	9	morphological	morphological	ADJ
fnp-3025	326	10	attributes	attribute	NOUN
fnp-3025	326	11	of	of	ADP
fnp-3025	326	12	plaques	plaque	NOUN
fnp-3025	326	13	might	might	AUX
fnp-3025	326	14	reflect	reflect	VERB
fnp-3025	326	15	,	,	PUNCT
fnp-3025	326	16	in	in	ADP
fnp-3025	326	17	addition	addition	NOUN
fnp-3025	326	18	to	to	ADP
fnp-3025	326	19	the	the	DET
fnp-3025	326	20	local	local	ADJ
fnp-3025	326	21	tissue	tissue	NOUN
fnp-3025	326	22	organization	organization	NOUN
fnp-3025	326	23	,	,	PUNCT
fnp-3025	326	24	the	the	DET
fnp-3025	326	25	variable	variable	ADJ
fnp-3025	326	26	truncation	truncation	NOUN
fnp-3025	326	27	,	,	PUNCT
fnp-3025	326	28	folding	folding	NOUN
fnp-3025	326	29	,	,	PUNCT
fnp-3025	326	30	and	and	CCONJ
fnp-3025	326	31	molecular	molecular	ADJ
fnp-3025	326	32	architecture	architecture	NOUN
fnp-3025	326	33	of	of	ADP
fnp-3025	326	34	aβ	aβ	NOUN
fnp-3025	326	35	[	[	X
fnp-3025	326	36	212	212	NUM
fnp-3025	326	37	,	,	PUNCT
fnp-3025	326	38	213	213	NUM
fnp-3025	326	39	]	]	PUNCT
fnp-3025	326	40	.	.	PUNCT
fnp-3025	327	1	these	these	DET
fnp-3025	327	2	variants	variant	NOUN
fnp-3025	327	3	are	be	AUX
fnp-3025	327	4	referred	refer	VERB
fnp-3025	327	5	to	to	ADP
fnp-3025	327	6	as	as	ADP
fnp-3025	327	7	proteopathic	proteopathic	ADJ
fnp-3025	327	8	strains	strain	NOUN
fnp-3025	327	9	,	,	PUNCT
fnp-3025	327	10	a	a	DET
fnp-3025	327	11	biological	biological	ADJ
fnp-3025	327	12	concept	concept	NOUN
fnp-3025	327	13	that	that	PRON
fnp-3025	327	14	was	be	AUX
fnp-3025	327	15	adopted	adopt	VERB
fnp-3025	327	16	by	by	ADP
fnp-3025	327	17	the	the	DET
fnp-3025	327	18	spongiform	spongiform	NOUN
fnp-3025	327	19	encephalopathy	encephalopathy	ADJ
fnp-3025	327	20	community	community	NOUN
fnp-3025	327	21	to	to	PART
fnp-3025	327	22	explain	explain	VERB
fnp-3025	327	23	the	the	DET
fnp-3025	327	24	alternative	alternative	ADJ
fnp-3025	327	25	disease	disease	NOUN
fnp-3025	327	26	phenotypes	phenotype	NOUN
fnp-3025	327	27	resulting	result	VERB
fnp-3025	327	28	from	from	ADP
fnp-3025	327	29	prion	prion	NOUN
fnp-3025	327	30	infections	infection	NOUN
fnp-3025	327	31	[	[	X
fnp-3025	327	32	214	214	NUM
fnp-3025	327	33	,	,	PUNCT
fnp-3025	327	34	215	215	NUM
fnp-3025	327	35	]	]	PUNCT
fnp-3025	327	36	.	.	PUNCT
fnp-3025	328	1	at	at	ADP
fnp-3025	328	2	the	the	DET
fnp-3025	328	3	molecular	molecular	ADJ
fnp-3025	328	4	level	level	NOUN
fnp-3025	328	5	,	,	PUNCT
fnp-3025	328	6	the	the	DET
fnp-3025	328	7	formation	formation	NOUN
fnp-3025	328	8	and	and	CCONJ
fnp-3025	328	9	propagation	propagation	NOUN
fnp-3025	328	10	of	of	ADP
fnp-3025	328	11	aβ	aβ	DET
fnp-3025	328	12	aggregates	aggregate	NOUN
fnp-3025	328	13	(	(	PUNCT
fnp-3025	328	14	as	as	ADV
fnp-3025	328	15	well	well	ADV
fnp-3025	328	16	as	as	ADP
fnp-3025	328	17	the	the	DET
fnp-3025	328	18	proteins	protein	NOUN
fnp-3025	328	19	involved	involve	VERB
fnp-3025	328	20	in	in	ADP
fnp-3025	328	21	several	several	ADJ
fnp-3025	328	22	other	other	ADJ
fnp-3025	328	23	proteopathies	proteopathie	NOUN
fnp-3025	328	24	[	[	X
fnp-3025	328	25	216	216	NUM
fnp-3025	328	26	]	]	NUM
fnp-3025	328	27	)	)	PUNCT
fnp-3025	328	28	,	,	PUNCT
fnp-3025	328	29	constitute	constitute	VERB
fnp-3025	328	30	a	a	DET
fnp-3025	328	31	mechanism	mechanism	NOUN
fnp-3025	328	32	that	that	PRON
fnp-3025	328	33	is	be	AUX
fnp-3025	328	34	fundamentally	fundamentally	ADV
fnp-3025	328	35	similar	similar	ADJ
fnp-3025	328	36	to	to	ADP
fnp-3025	328	37	that	that	PRON
fnp-3025	328	38	of	of	ADP
fnp-3025	328	39	prions	prion	NOUN
fnp-3025	328	40	[	[	X
fnp-3025	328	41	217	217	NUM
fnp-3025	328	42	,	,	PUNCT
fnp-3025	328	43	218	218	NUM
fnp-3025	328	44	]	]	PUNCT
fnp-3025	328	45	(	(	PUNCT
fnp-3025	328	46	see	see	VERB
fnp-3025	328	47	section	section	NOUN
fnp-3025	328	48	9	9	NUM
fnp-3025	328	49	)	)	PUNCT
fnp-3025	328	50	.	.	PUNCT
fnp-3025	329	1	the	the	DET
fnp-3025	329	2	capacity	capacity	NOUN
fnp-3025	329	3	to	to	PART
fnp-3025	329	4	spawn	spawn	VERB
fnp-3025	329	5	distinct	distinct	ADJ
fnp-3025	329	6	strains	strain	NOUN
fnp-3025	329	7	is	be	AUX
fnp-3025	329	8	considered	consider	VERB
fnp-3025	329	9	to	to	PART
fnp-3025	329	10	be	be	AUX
fnp-3025	329	11	a	a	DET
fnp-3025	329	12	shared	share	VERB
fnp-3025	329	13	property	property	NOUN
fnp-3025	329	14	of	of	ADP
fnp-3025	329	15	proteins	protein	NOUN
fnp-3025	329	16	that	that	PRON
fnp-3025	329	17	are	be	AUX
fnp-3025	329	18	prone	prone	ADJ
fnp-3025	329	19	to	to	ADP
fnp-3025	329	20	misfolding	misfolding	NOUN
fnp-3025	329	21	and	and	CCONJ
fnp-3025	329	22	self	self	NOUN
fnp-3025	329	23	-	-	PUNCT
fnp-3025	329	24	assembly	assembly	NOUN
fnp-3025	329	25	[	[	X
fnp-3025	329	26	56	56	NUM
fnp-3025	329	27	,	,	PUNCT
fnp-3025	329	28	59	59	NUM
fnp-3025	329	29	,	,	PUNCT
fnp-3025	329	30	219	219	NUM
fnp-3025	329	31	]	]	PUNCT
fnp-3025	329	32	.	.	PUNCT
fnp-3025	330	1	in	in	ADP
fnp-3025	330	2	vitro	vitro	X
fnp-3025	330	3	,	,	PUNCT
fnp-3025	330	4	a	a	DET
fnp-3025	330	5	given	give	VERB
fnp-3025	330	6	protein	protein	NOUN
fnp-3025	330	7	can	can	AUX
fnp-3025	330	8	create	create	VERB
fnp-3025	330	9	morphologically	morphologically	ADV
fnp-3025	330	10	diverse	diverse	ADJ
fnp-3025	330	11	amyloid	amyloid	NOUN
fnp-3025	330	12	fibrils	fibril	NOUN
fnp-3025	330	13	under	under	ADP
fnp-3025	330	14	different	different	ADJ
fnp-3025	330	15	environmental	environmental	ADJ
fnp-3025	330	16	influences	influence	NOUN
fnp-3025	330	17	,	,	PUNCT
fnp-3025	330	18	for	for	ADP
fnp-3025	330	19	example	example	NOUN
fnp-3025	330	20	temperature	temperature	NOUN
fnp-3025	330	21	,	,	PUNCT
fnp-3025	330	22	ph	ph	ADJ
fnp-3025	330	23	,	,	PUNCT
fnp-3025	330	24	ionic	ionic	ADJ
fnp-3025	330	25	strength	strength	NOUN
fnp-3025	330	26	,	,	PUNCT
fnp-3025	330	27	protein	protein	NOUN
fnp-3025	330	28	concentration	concentration	NOUN
fnp-3025	330	29	[	[	X
fnp-3025	330	30	220	220	NUM
fnp-3025	330	31	,	,	PUNCT
fnp-3025	330	32	221	221	NUM
fnp-3025	330	33	]	]	PUNCT
fnp-3025	330	34	and	and	CCONJ
fnp-3025	330	35	agitation	agitation	NOUN
fnp-3025	330	36	[	[	X
fnp-3025	330	37	67	67	NUM
fnp-3025	330	38	,	,	PUNCT
fnp-3025	330	39	222	222	NUM
fnp-3025	330	40	]	]	PUNCT
fnp-3025	330	41	.	.	PUNCT
fnp-3025	331	1	strain	strain	NOUN
fnp-3025	331	2	properties	property	NOUN
fnp-3025	331	3	can	can	AUX
fnp-3025	331	4	be	be	AUX
fnp-3025	331	5	conveyed	convey	VERB
fnp-3025	331	6	to	to	ADP
fnp-3025	331	7	newly	newly	ADV
fnp-3025	331	8	forming	form	VERB
fnp-3025	331	9	amyloid	amyloid	NOUN
fnp-3025	331	10	fibrils	fibril	NOUN
fnp-3025	331	11	;	;	PUNCT
fnp-3025	331	12	in	in	ADP
fnp-3025	331	13	vivo	vivo	NOUN
fnp-3025	331	14	,	,	PUNCT
fnp-3025	331	15	it	it	PRON
fnp-3025	331	16	is	be	AUX
fnp-3025	331	17	thought	think	VERB
fnp-3025	331	18	that	that	SCONJ
fnp-3025	331	19	proteopathic	proteopathic	ADJ
fnp-3025	331	20	strains	strain	NOUN
fnp-3025	331	21	undergo	undergo	VERB
fnp-3025	331	22	conformational	conformational	ADJ
fnp-3025	331	23	selection	selection	NOUN
fnp-3025	331	24	by	by	ADP
fnp-3025	331	25	which	which	PRON
fnp-3025	331	26	the	the	DET
fnp-3025	331	27	strain	strain	NOUN
fnp-3025	331	28	best	well	ADV
fnp-3025	331	29	suited	suit	VERB
fnp-3025	331	30	to	to	ADP
fnp-3025	331	31	a	a	DET
fnp-3025	331	32	given	give	VERB
fnp-3025	331	33	environment	environment	NOUN
fnp-3025	331	34	predominates	predominate	VERB
fnp-3025	331	35	[	[	X
fnp-3025	331	36	215	215	NUM
fnp-3025	331	37	,	,	PUNCT
fnp-3025	331	38	220	220	NUM
fnp-3025	331	39	,	,	PUNCT
fnp-3025	331	40	223	223	NUM
fnp-3025	331	41	,	,	PUNCT
fnp-3025	331	42	224	224	NUM
fnp-3025	331	43	]	]	PUNCT
fnp-3025	331	44	.	.	PUNCT
fnp-3025	332	1	studies	study	NOUN
fnp-3025	332	2	in	in	ADP
fnp-3025	332	3	genetically	genetically	ADV
fnp-3025	332	4	modified	modify	VERB
fnp-3025	332	5	mouse	mouse	NOUN
fnp-3025	332	6	models	model	NOUN
fnp-3025	332	7	(	(	PUNCT
fnp-3025	332	8	which	which	PRON
fnp-3025	332	9	can	can	AUX
fnp-3025	332	10	be	be	AUX
fnp-3025	332	11	customized	customize	VERB
fnp-3025	332	12	to	to	PART
fnp-3025	332	13	make	make	VERB
fnp-3025	332	14	various	various	ADJ
fnp-3025	332	15	types	type	NOUN
fnp-3025	332	16	of	of	ADP
fnp-3025	332	17	aβ	aβ	NOUN
fnp-3025	332	18	)	)	PUNCT
fnp-3025	332	19	can	can	AUX
fnp-3025	332	20	shed	shed	VERB
fnp-3025	332	21	light	light	NOUN
fnp-3025	332	22	on	on	ADP
fnp-3025	332	23	the	the	DET
fnp-3025	332	24	factors	factor	NOUN
fnp-3025	332	25	that	that	PRON
fnp-3025	332	26	govern	govern	VERB
fnp-3025	332	27	alternative	alternative	ADJ
fnp-3025	332	28	plaque	plaque	NOUN
fnp-3025	332	29	morphologies	morphology	NOUN
fnp-3025	332	30	in	in	ADP
fnp-3025	332	31	the	the	DET
fnp-3025	332	32	living	live	VERB
fnp-3025	332	33	brain	brain	NOUN
fnp-3025	332	34	[	[	X
fnp-3025	332	35	225	225	NUM
fnp-3025	332	36	]	]	PUNCT
fnp-3025	332	37	.	.	PUNCT
fnp-3025	333	1	the	the	DET
fnp-3025	333	2	generation	generation	NOUN
fnp-3025	333	3	of	of	ADP
fnp-3025	333	4	aβ	aβ	PRON
fnp-3025	333	5	strains	strain	NOUN
fnp-3025	333	6	is	be	AUX
fnp-3025	333	7	influenced	influence	VERB
fnp-3025	333	8	by	by	ADP
fnp-3025	333	9	characteristics	characteristic	NOUN
fnp-3025	333	10	of	of	ADP
fnp-3025	333	11	the	the	DET
fnp-3025	333	12	aggregating	aggregating	NOUN
fnp-3025	333	13	aβ	aβ	NOUN
fnp-3025	333	14	such	such	ADJ
fnp-3025	333	15	as	as	ADP
fnp-3025	333	16	mutations	mutation	NOUN
fnp-3025	333	17	,	,	PUNCT
fnp-3025	333	18	truncations	truncation	NOUN
fnp-3025	333	19	and	and	CCONJ
fnp-3025	333	20	chemical	chemical	NOUN
fnp-3025	333	21	modifications	modification	NOUN
fnp-3025	333	22	(	(	PUNCT
fnp-3025	333	23	see	see	VERB
fnp-3025	333	24	sections	section	NOUN
fnp-3025	333	25	1	1	NUM
fnp-3025	333	26	and	and	CCONJ
fnp-3025	333	27	7	7	NUM
fnp-3025	333	28	)	)	PUNCT
fnp-3025	333	29	.	.	PUNCT
fnp-3025	334	1	aβ	aβ	PRON
fnp-3025	334	2	forms	form	VERB
fnp-3025	334	3	distinct	distinct	ADJ
fnp-3025	334	4	structural	structural	ADJ
fnp-3025	334	5	strains	strain	NOUN
fnp-3025	334	6	in	in	ADP
fnp-3025	334	7	different	different	ADJ
fnp-3025	334	8	subtypes	subtype	NOUN
fnp-3025	334	9	of	of	ADP
fnp-3025	334	10	ad	ad	NOUN
fnp-3025	334	11	[	[	X
fnp-3025	334	12	226	226	NUM
fnp-3025	334	13	-	-	SYM
fnp-3025	334	14	231	231	NUM
fnp-3025	334	15	]	]	PUNCT
fnp-3025	334	16	.	.	PUNCT
fnp-3025	335	1	investigations	investigation	NOUN
fnp-3025	335	2	of	of	ADP
fnp-3025	335	3	the	the	DET
fnp-3025	335	4	molecular	molecular	ADJ
fnp-3025	335	5	configuration	configuration	NOUN
fnp-3025	335	6	of	of	ADP
fnp-3025	335	7	aβ	aβ	NOUN
fnp-3025	335	8	fibrils	fibril	NOUN
fnp-3025	335	9	in	in	ADP
fnp-3025	335	10	vitro	vitro	ADJ
fnp-3025	335	11	have	have	AUX
fnp-3025	335	12	yielded	yield	VERB
fnp-3025	335	13	insights	insight	NOUN
fnp-3025	335	14	into	into	ADP
fnp-3025	335	15	potential	potential	ADJ
fnp-3025	335	16	determinants	determinant	NOUN
fnp-3025	335	17	of	of	ADP
fnp-3025	335	18	aβ	aβ	DET
fnp-3025	335	19	strains	strain	NOUN
fnp-3025	335	20	(	(	PUNCT
fnp-3025	335	21	see	see	VERB
fnp-3025	335	22	,	,	PUNCT
fnp-3025	335	23	e.g.	e.g.	ADV
fnp-3025	335	24	,	,	PUNCT
fnp-3025	335	25	[	[	X
fnp-3025	335	26	228	228	NUM
fnp-3025	335	27	,	,	PUNCT
fnp-3025	335	28	232	232	NUM
fnp-3025	335	29	-	-	SYM
fnp-3025	335	30	235	235	NUM
fnp-3025	335	31	]	]	PUNCT
fnp-3025	335	32	)	)	PUNCT
fnp-3025	335	33	,	,	PUNCT
fnp-3025	335	34	but	but	CCONJ
fnp-3025	335	35	cryo	cryo	NOUN
fnp-3025	335	36	-	-	PUNCT
fnp-3025	335	37	electron	electron	NOUN
fnp-3025	335	38	microscopic	microscopic	ADJ
fnp-3025	335	39	analysis	analysis	NOUN
fnp-3025	335	40	of	of	ADP
fnp-3025	335	41	meningovascular	meningovascular	ADJ
fnp-3025	335	42	aβ	aβ	NOUN
fnp-3025	335	43	-	-	PUNCT
fnp-3025	335	44	amyloid	amyloid	NOUN
fnp-3025	335	45	indicates	indicate	VERB
fnp-3025	335	46	that	that	SCONJ
fnp-3025	335	47	aβ	aβ	NOUN
fnp-3025	335	48	-	-	PUNCT
fnp-3025	335	49	caa	caa	NOUN
fnp-3025	335	50	fibrils	fibril	NOUN
fnp-3025	335	51	formed	form	VERB
fnp-3025	335	52	in	in	ADP
fnp-3025	335	53	vivo	vivo	NOUN
fnp-3025	335	54	,	,	PUNCT
fnp-3025	335	55	though	though	SCONJ
fnp-3025	335	56	polymorphic	polymorphic	ADJ
fnp-3025	335	57	,	,	PUNCT
fnp-3025	335	58	differ	differ	VERB
fnp-3025	335	59	in	in	ADP
fnp-3025	335	60	important	important	ADJ
fnp-3025	335	61	ways	way	NOUN
fnp-3025	335	62	from	from	ADP
fnp-3025	335	63	those	those	PRON
fnp-3025	335	64	formed	form	VERB
fnp-3025	335	65	in	in	ADP
fnp-3025	335	66	vitro	vitro	X
fnp-3025	336	1	[	[	X
fnp-3025	336	2	66	66	NUM
fnp-3025	336	3	]	]	PUNCT
fnp-3025	336	4	.	.	PUNCT
fnp-3025	337	1	a	a	DET
fnp-3025	337	2	similar	similar	ADJ
fnp-3025	337	3	analytic	analytic	ADJ
fnp-3025	337	4	comparison	comparison	NOUN
fnp-3025	337	5	of	of	ADP
fnp-3025	337	6	aβ	aβ	NOUN
fnp-3025	337	7	fibrils	fibril	NOUN
fnp-3025	337	8	from	from	ADP
fnp-3025	337	9	plaques	plaque	NOUN
fnp-3025	337	10	in	in	ADP
fnp-3025	337	11	the	the	DET
fnp-3025	337	12	brain	brain	NOUN
fnp-3025	337	13	parenchyma	parenchyma	NOUN
fnp-3025	337	14	and	and	CCONJ
fnp-3025	337	15	caa	caa	NOUN
fnp-3025	337	16	could	could	AUX
fnp-3025	337	17	help	help	VERB
fnp-3025	337	18	to	to	PART
fnp-3025	337	19	explain	explain	VERB
fnp-3025	337	20	the	the	DET
fnp-3025	337	21	inconsistent	inconsistent	ADJ
fnp-3025	337	22	co	co	NOUN
fnp-3025	337	23	-	-	NOUN
fnp-3025	337	24	presence	presence	NOUN
fnp-3025	337	25	of	of	ADP
fnp-3025	337	26	plaques	plaque	NOUN
fnp-3025	337	27	and	and	CCONJ
fnp-3025	337	28	amyloid	amyloid	VERB
fnp-3025	337	29	angiopathy	angiopathy	NOUN
fnp-3025	337	30	in	in	ADP
fnp-3025	337	31	ad	ad	NOUN
fnp-3025	337	32	.	.	PUNCT
fnp-3025	338	1	5.3	5.3	NUM
fnp-3025	338	2	cerebral	cerebral	ADJ
fnp-3025	338	3	aβ	aβ	NOUN
fnp-3025	338	4	-	-	PUNCT
fnp-3025	338	5	amyloid	amyloid	NOUN
fnp-3025	338	6	angiopathy	angiopathy	NOUN
fnp-3025	338	7	(	(	PUNCT
fnp-3025	338	8	aβ	aβ	NOUN
fnp-3025	338	9	-	-	PUNCT
fnp-3025	338	10	caa	caa	NOUN
fnp-3025	338	11	)	)	PUNCT
fnp-3025	338	12	several	several	ADJ
fnp-3025	338	13	different	different	ADJ
fnp-3025	338	14	proteins	protein	NOUN
fnp-3025	338	15	can	can	AUX
fnp-3025	338	16	form	form	VERB
fnp-3025	338	17	caa	caa	NOUN
fnp-3025	338	18	in	in	ADP
fnp-3025	338	19	different	different	ADJ
fnp-3025	338	20	disorders	disorder	NOUN
fnp-3025	338	21	,	,	PUNCT
fnp-3025	338	22	but	but	CCONJ
fnp-3025	338	23	aβ	aβ	PRON
fnp-3025	338	24	is	be	AUX
fnp-3025	338	25	the	the	DET
fnp-3025	338	26	most	most	ADV
fnp-3025	338	27	common	common	ADJ
fnp-3025	338	28	source	source	NOUN
fnp-3025	338	29	of	of	ADP
fnp-3025	338	30	caa	caa	NOUN
fnp-3025	338	31	in	in	ADP
fnp-3025	338	32	the	the	DET
fnp-3025	338	33	elderly	elderly	ADJ
fnp-3025	338	34	[	[	X
fnp-3025	338	35	236	236	NUM
fnp-3025	338	36	]	]	PUNCT
fnp-3025	338	37	.	.	PUNCT
fnp-3025	339	1	aβ	aβ	PRON
fnp-3025	339	2	accumulates	accumulate	VERB
fnp-3025	339	3	in	in	ADP
fnp-3025	339	4	the	the	DET
fnp-3025	339	5	vascular	vascular	ADJ
fnp-3025	339	6	wall	wall	NOUN
fnp-3025	339	7	and	and	CCONJ
fnp-3025	339	8	perivascular	perivascular	ADJ
fnp-3025	339	9	zone	zone	NOUN
fnp-3025	339	10	in	in	ADP
fnp-3025	339	11	cases	case	NOUN
fnp-3025	339	12	of	of	ADP
fnp-3025	339	13	primary	primary	ADJ
fnp-3025	339	14	aβ	aβ	NOUN
fnp-3025	339	15	-	-	PUNCT
fnp-3025	339	16	caa	caa	NOUN
fnp-3025	339	17	involving	involve	VERB
fnp-3025	339	18	mutations	mutation	NOUN
fnp-3025	339	19	in	in	ADP
fnp-3025	339	20	the	the	DET
fnp-3025	339	21	gene	gene	NOUN
fnp-3025	339	22	for	for	ADP
fnp-3025	339	23	app	app	NOUN
fnp-3025	339	24	[	[	X
fnp-3025	339	25	21	21	NUM
fnp-3025	339	26	,	,	PUNCT
fnp-3025	339	27	237	237	NUM
fnp-3025	339	28	-	-	SYM
fnp-3025	339	29	240	240	NUM
fnp-3025	339	30	]	]	PUNCT
fnp-3025	339	31	and	and	CCONJ
fnp-3025	339	32	to	to	ADP
fnp-3025	339	33	varying	vary	VERB
fnp-3025	339	34	degrees	degree	NOUN
fnp-3025	339	35	in	in	ADP
fnp-3025	339	36	nearly	nearly	ADV
fnp-3025	339	37	all	all	PRON
fnp-3025	339	38	cases	case	NOUN
fnp-3025	339	39	of	of	ADP
fnp-3025	339	40	ad	ad	NOUN
fnp-3025	339	41	[	[	X
fnp-3025	339	42	241	241	NUM
fnp-3025	339	43	-	-	SYM
fnp-3025	339	44	244	244	NUM
fnp-3025	339	45	]	]	PUNCT
fnp-3025	339	46	.	.	PUNCT
fnp-3025	340	1	ad	ad	NOUN
fnp-3025	340	2	and	and	CCONJ
fnp-3025	340	3	aβ	aβ	NOUN
fnp-3025	340	4	-	-	PUNCT
fnp-3025	340	5	caa	caa	NOUN
fnp-3025	340	6	share	share	VERB
fnp-3025	340	7	many	many	ADJ
fnp-3025	340	8	genetic	genetic	ADJ
fnp-3025	340	9	risk	risk	NOUN
fnp-3025	340	10	factors	factor	NOUN
fnp-3025	340	11	,	,	PUNCT
fnp-3025	340	12	and	and	CCONJ
fnp-3025	340	13	like	like	INTJ
fnp-3025	340	14	aβ	aβ	DET
fnp-3025	340	15	plaques	plaque	NOUN
fnp-3025	340	16	,	,	PUNCT
fnp-3025	340	17	idiopathic	idiopathic	ADJ
fnp-3025	340	18	aβ	aβ	NOUN
fnp-3025	340	19	-	-	PUNCT
fnp-3025	340	20	caa	caa	NOUN
fnp-3025	340	21	sometimes	sometimes	ADV
fnp-3025	340	22	is	be	AUX
fnp-3025	340	23	present	present	ADJ
fnp-3025	340	24	in	in	ADP
fnp-3025	340	25	the	the	DET
fnp-3025	340	26	nondemented	nondemented	ADJ
fnp-3025	340	27	elderly	elderly	ADJ
fnp-3025	340	28	[	[	X
fnp-3025	340	29	240	240	NUM
fnp-3025	340	30	,	,	PUNCT
fnp-3025	340	31	241	241	NUM
fnp-3025	340	32	]	]	PUNCT
fnp-3025	340	33	.	.	PUNCT
fnp-3025	341	1	caa	caa	PROPN
fnp-3025	341	2	is	be	AUX
fnp-3025	341	3	a	a	DET
fnp-3025	341	4	significant	significant	ADJ
fnp-3025	341	5	risk	risk	NOUN
fnp-3025	341	6	factor	factor	NOUN
fnp-3025	341	7	for	for	ADP
fnp-3025	341	8	lobar	lobar	ADJ
fnp-3025	341	9	hemorrhage	hemorrhage	NOUN
fnp-3025	341	10	[	[	X
fnp-3025	341	11	236	236	NUM
fnp-3025	341	12	,	,	PUNCT
fnp-3025	341	13	245	245	NUM
fnp-3025	341	14	]	]	PUNCT
fnp-3025	341	15	,	,	PUNCT
fnp-3025	341	16	particularly	particularly	ADV
fnp-3025	341	17	in	in	ADP
fnp-3025	341	18	individuals	individual	NOUN
fnp-3025	341	19	with	with	ADP
fnp-3025	341	20	hypertension	hypertension	NOUN
fnp-3025	341	21	[	[	X
fnp-3025	341	22	246	246	NUM
fnp-3025	341	23	]	]	PUNCT
fnp-3025	341	24	.	.	PUNCT
fnp-3025	342	1	in	in	ADP
fnp-3025	342	2	end	end	NOUN
fnp-3025	342	3	-	-	PUNCT
fnp-3025	342	4	stage	stage	NOUN
fnp-3025	342	5	ad	ad	NOUN
fnp-3025	342	6	,	,	PUNCT
fnp-3025	342	7	the	the	DET
fnp-3025	342	8	amount	amount	NOUN
fnp-3025	342	9	of	of	ADP
fnp-3025	342	10	aβ	aβ	NOUN
fnp-3025	342	11	-	-	PUNCT
fnp-3025	342	12	caa	caa	NOUN
fnp-3025	342	13	varies	vary	VERB
fnp-3025	342	14	widely	widely	ADV
fnp-3025	342	15	,	,	PUNCT
fnp-3025	342	16	even	even	ADV
fnp-3025	342	17	in	in	ADP
fnp-3025	342	18	the	the	DET
fnp-3025	342	19	presence	presence	NOUN
fnp-3025	342	20	of	of	ADP
fnp-3025	342	21	copious	copious	ADJ
fnp-3025	342	22	plaques	plaque	NOUN
fnp-3025	342	23	[	[	X
fnp-3025	342	24	247	247	NUM
fnp-3025	342	25	]	]	PUNCT
fnp-3025	342	26	,	,	PUNCT
fnp-3025	342	27	although	although	SCONJ
fnp-3025	342	28	the	the	DET
fnp-3025	342	29	severity	severity	NOUN
fnp-3025	342	30	of	of	ADP
fnp-3025	342	31	aβ	aβ	NOUN
fnp-3025	342	32	-	-	PUNCT
fnp-3025	342	33	caa	caa	NOUN
fnp-3025	342	34	tends	tend	VERB
fnp-3025	342	35	to	to	PART
fnp-3025	342	36	increase	increase	VERB
fnp-3025	342	37	with	with	ADP
fnp-3025	342	38	increasing	increase	VERB
fnp-3025	342	39	plaque	plaque	NOUN
fnp-3025	342	40	load	load	NOUN
fnp-3025	342	41	[	[	X
fnp-3025	342	42	21	21	NUM
fnp-3025	342	43	]	]	PUNCT
fnp-3025	342	44	.	.	PUNCT
fnp-3025	343	1	furthermore	furthermore	ADV
fnp-3025	343	2	,	,	PUNCT
fnp-3025	343	3	in	in	ADP
fnp-3025	343	4	some	some	DET
fnp-3025	343	5	instances	instance	NOUN
fnp-3025	343	6	,	,	PUNCT
fnp-3025	343	7	aβ	aβ	PRON
fnp-3025	343	8	-	-	PUNCT
fnp-3025	343	9	caa	caa	NOUN
fnp-3025	343	10	can	can	AUX
fnp-3025	343	11	emerge	emerge	VERB
fnp-3025	343	12	in	in	ADP
fnp-3025	343	13	the	the	DET
fnp-3025	343	14	absence	absence	NOUN
fnp-3025	343	15	or	or	CCONJ
fnp-3025	343	16	near	near	ADP
fnp-3025	343	17	absence	absence	NOUN
fnp-3025	343	18	of	of	ADP
fnp-3025	343	19	aβ	aβ	DET
fnp-3025	343	20	plaques	plaque	NOUN
fnp-3025	343	21	,	,	PUNCT
fnp-3025	343	22	notably	notably	ADV
fnp-3025	343	23	in	in	ADP
fnp-3025	343	24	an	an	DET
fnp-3025	343	25	autosomal	autosomal	ADJ
fnp-3025	343	26	dominant	dominant	ADJ
fnp-3025	343	27	form	form	NOUN
fnp-3025	343	28	of	of	ADP
fnp-3025	343	29	aβ	aβ	NOUN
fnp-3025	343	30	-	-	PUNCT
fnp-3025	343	31	caa	caa	NOUN
fnp-3025	343	32	known	know	VERB
fnp-3025	343	33	as	as	ADP
fnp-3025	343	34	hereditary	hereditary	ADJ
fnp-3025	343	35	cerebral	cerebral	ADJ
fnp-3025	343	36	hemorrhage	hemorrhage	NOUN
fnp-3025	343	37	with	with	ADP
fnp-3025	343	38	amyloidosis	amyloidosis	NOUN
fnp-3025	343	39	(	(	PUNCT
fnp-3025	343	40	dutch	dutch	ADJ
fnp-3025	343	41	type	type	NOUN
fnp-3025	343	42	)	)	PUNCT
fnp-3025	343	43	(	(	PUNCT
fnp-3025	343	44	hchwa	hchwa	PROPN
fnp-3025	343	45	-	-	PUNCT
fnp-3025	343	46	d	d	NOUN
fnp-3025	343	47	)	)	PUNCT
fnp-3025	344	1	[	[	X
fnp-3025	344	2	239	239	NUM
fnp-3025	344	3	,	,	PUNCT
fnp-3025	344	4	248	248	NUM
fnp-3025	344	5	,	,	PUNCT
fnp-3025	344	6	249	249	NUM
fnp-3025	344	7	]	]	PUNCT
fnp-3025	344	8	.	.	PUNCT
fnp-3025	345	1	there	there	PRON
fnp-3025	345	2	is	be	VERB
fnp-3025	345	3	evidence	evidence	NOUN
fnp-3025	345	4	for	for	ADP
fnp-3025	345	5	some	some	DET
fnp-3025	345	6	diffuse	diffuse	ADJ
fnp-3025	345	7	parenchymal	parenchymal	ADJ
fnp-3025	345	8	aβ	aβ	NOUN
fnp-3025	345	9	deposition	deposition	NOUN
fnp-3025	345	10	[	[	X
fnp-3025	345	11	250	250	NUM
fnp-3025	345	12	,	,	PUNCT
fnp-3025	345	13	251	251	NUM
fnp-3025	345	14	]	]	PUNCT
fnp-3025	345	15	and	and	CCONJ
fnp-3025	345	16	cognitive	cognitive	ADJ
fnp-3025	345	17	decline	decline	NOUN
fnp-3025	345	18	[	[	X
fnp-3025	345	19	238	238	NUM
fnp-3025	345	20	,	,	PUNCT
fnp-3025	345	21	252	252	NUM
fnp-3025	345	22	]	]	PUNCT
fnp-3025	345	23	in	in	ADP
fnp-3025	345	24	these	these	DET
fnp-3025	345	25	cases	case	NOUN
fnp-3025	345	26	,	,	PUNCT
fnp-3025	345	27	but	but	CCONJ
fnp-3025	345	28	the	the	DET
fnp-3025	345	29	clinical	clinical	ADJ
fnp-3025	345	30	phenotype	phenotype	NOUN
fnp-3025	345	31	probably	probably	ADV
fnp-3025	345	32	reflects	reflect	VERB
fnp-3025	345	33	the	the	DET
fnp-3025	345	34	vascular	vascular	ADJ
fnp-3025	345	35	pathology	pathology	NOUN
fnp-3025	345	36	more	more	ADJ
fnp-3025	345	37	than	than	ADP
fnp-3025	345	38	an	an	DET
fnp-3025	345	39	ad	ad	NOUN
fnp-3025	345	40	-	-	PUNCT
fnp-3025	345	41	like	like	ADJ
fnp-3025	345	42	disorder	disorder	NOUN
fnp-3025	345	43	in	in	ADP
fnp-3025	345	44	which	which	PRON
fnp-3025	345	45	plaques	plaque	NOUN
fnp-3025	345	46	and	and	CCONJ
fnp-3025	345	47	tangles	tangle	NOUN
fnp-3025	345	48	are	be	AUX
fnp-3025	345	49	abundant	abundant	ADJ
fnp-3025	345	50	[	[	X
fnp-3025	345	51	253	253	NUM
fnp-3025	345	52	]	]	PUNCT
fnp-3025	345	53	.	.	PUNCT
fnp-3025	346	1	cognitive	cognitive	ADJ
fnp-3025	346	2	dysfunction	dysfunction	NOUN
fnp-3025	346	3	[	[	X
fnp-3025	346	4	254	254	NUM
fnp-3025	346	5	-	-	SYM
fnp-3025	346	6	258	258	NUM
fnp-3025	346	7	]	]	PUNCT
fnp-3025	346	8	and	and	CCONJ
fnp-3025	346	9	neurodegenerative	neurodegenerative	ADJ
fnp-3025	346	10	changes	change	NOUN
fnp-3025	346	11	[	[	X
fnp-3025	346	12	259	259	NUM
fnp-3025	346	13	]	]	PUNCT
fnp-3025	346	14	also	also	ADV
fnp-3025	346	15	have	have	AUX
fnp-3025	346	16	been	be	AUX
fnp-3025	346	17	associated	associate	VERB
fnp-3025	346	18	with	with	ADP
fnp-3025	346	19	idiopathic	idiopathic	ADJ
fnp-3025	346	20	aβ	aβ	NOUN
fnp-3025	346	21	-	-	PUNCT
fnp-3025	346	22	caa	caa	NOUN
fnp-3025	346	23	.	.	PUNCT
fnp-3025	347	1	in	in	ADP
fnp-3025	347	2	approximately	approximately	ADV
fnp-3025	347	3	25	25	NUM
fnp-3025	347	4	%	%	NOUN
fnp-3025	347	5	of	of	ADP
fnp-3025	347	6	end	end	NOUN
fnp-3025	347	7	-	-	PUNCT
fnp-3025	347	8	stage	stage	NOUN
fnp-3025	347	9	ad	ad	NOUN
fnp-3025	347	10	patients	patient	NOUN
fnp-3025	347	11	,	,	PUNCT
fnp-3025	347	12	aβ	aβ	PRON
fnp-3025	347	13	-	-	PUNCT
fnp-3025	347	14	caa	caa	NOUN
fnp-3025	347	15	affecting	affect	VERB
fnp-3025	347	16	large	large	ADJ
fnp-3025	347	17	vessels	vessel	NOUN
fnp-3025	347	18	is	be	AUX
fnp-3025	347	19	considered	consider	VERB
fnp-3025	347	20	to	to	PART
fnp-3025	347	21	be	be	AUX
fnp-3025	347	22	severe	severe	ADJ
fnp-3025	347	23	(	(	PUNCT
fnp-3025	347	24	arterioles	arteriole	NOUN
fnp-3025	347	25	are	be	AUX
fnp-3025	347	26	more	more	ADV
fnp-3025	347	27	often	often	ADV
fnp-3025	347	28	afflicted	afflict	VERB
fnp-3025	347	29	than	than	SCONJ
fnp-3025	347	30	are	be	AUX
fnp-3025	347	31	veins	vein	NOUN
fnp-3025	347	32	)	)	PUNCT
fnp-3025	347	33	;	;	PUNCT
fnp-3025	347	34	capillary	capillary	ADJ
fnp-3025	347	35	aβ	aβ	NOUN
fnp-3025	347	36	-	-	PUNCT
fnp-3025	347	37	caa	caa	NOUN
fnp-3025	347	38	is	be	AUX
fnp-3025	347	39	less	less	ADV
fnp-3025	347	40	common	common	ADJ
fnp-3025	347	41	,	,	PUNCT
fnp-3025	347	42	being	be	AUX
fnp-3025	347	43	severe	severe	ADJ
fnp-3025	347	44	in	in	ADP
fnp-3025	347	45	approximately	approximately	ADV
fnp-3025	347	46	10	10	NUM
fnp-3025	347	47	%	%	NOUN
fnp-3025	347	48	of	of	ADP
fnp-3025	347	49	cases	case	NOUN
fnp-3025	347	50	[	[	X
fnp-3025	347	51	247	247	NUM
fnp-3025	347	52	]	]	PUNCT
fnp-3025	347	53	.	.	PUNCT
fnp-3025	348	1	in	in	ADP
fnp-3025	348	2	advanced	advanced	ADJ
fnp-3025	348	3	aβ	aβ	NOUN
fnp-3025	348	4	-	-	PUNCT
fnp-3025	348	5	caa	caa	NOUN
fnp-3025	348	6	,	,	PUNCT
fnp-3025	348	7	the	the	DET
fnp-3025	348	8	amyloid	amyloid	NOUN
fnp-3025	348	9	often	often	ADV
fnp-3025	348	10	extends	extend	VERB
fnp-3025	348	11	through	through	ADP
fnp-3025	348	12	the	the	DET
fnp-3025	348	13	tunica	tunica	PROPN
fnp-3025	348	14	adventitia	adventitia	PROPN
fnp-3025	348	15	and	and	CCONJ
fnp-3025	348	16	into	into	ADP
fnp-3025	348	17	the	the	DET
fnp-3025	348	18	surrounding	surround	VERB
fnp-3025	348	19	parenchyma	parenchyma	NOUN
fnp-3025	348	20	,	,	PUNCT
fnp-3025	348	21	where	where	SCONJ
fnp-3025	348	22	it	it	PRON
fnp-3025	348	23	is	be	AUX
fnp-3025	348	24	pervaded	pervade	VERB
fnp-3025	348	25	by	by	ADP
fnp-3025	348	26	tau	tau	PROPN
fnp-3025	348	27	-	-	PUNCT
fnp-3025	348	28	immunoreactive	immunoreactive	ADJ
fnp-3025	348	29	abnormal	abnormal	ADJ
fnp-3025	348	30	neurites	neurite	NOUN
fnp-3025	348	31	[	[	X
fnp-3025	348	32	25	25	NUM
fnp-3025	348	33	,	,	PUNCT
fnp-3025	348	34	260	260	NUM
fnp-3025	348	35	,	,	PUNCT
fnp-3025	348	36	261	261	NUM
fnp-3025	348	37	]	]	PUNCT
fnp-3025	348	38	(	(	PUNCT
fnp-3025	348	39	figure	figure	NOUN
fnp-3025	348	40	15	15	NUM
fnp-3025	348	41	)	)	PUNCT
fnp-3025	348	42	.	.	PUNCT
fnp-3025	349	1	for	for	ADP
fnp-3025	349	2	unknown	unknown	ADJ
fnp-3025	349	3	reasons	reason	NOUN
fnp-3025	349	4	,	,	PUNCT
fnp-3025	349	5	in	in	ADP
fnp-3025	349	6	regions	region	NOUN
fnp-3025	349	7	of	of	ADP
fnp-3025	349	8	the	the	DET
fnp-3025	349	9	neocortex	neocortex	NOUN
fnp-3025	349	10	where	where	SCONJ
fnp-3025	349	11	capillary	capillary	ADJ
fnp-3025	349	12	aβ	aβ	NOUN
fnp-3025	349	13	-	-	PUNCT
fnp-3025	349	14	caa	caa	NOUN
fnp-3025	349	15	is	be	AUX
fnp-3025	349	16	focally	focally	ADV
fnp-3025	349	17	abundant	abundant	ADJ
fnp-3025	349	18	,	,	PUNCT
fnp-3025	349	19	aβ	aβ	DET
fnp-3025	349	20	plaques	plaque	NOUN
fnp-3025	349	21	are	be	AUX
fnp-3025	349	22	relatively	relatively	ADV
fnp-3025	349	23	scarce	scarce	ADJ
fnp-3025	349	24	[	[	X
fnp-3025	349	25	25	25	NUM
fnp-3025	349	26	,	,	PUNCT
fnp-3025	349	27	247	247	NUM
fnp-3025	349	28	,	,	PUNCT
fnp-3025	349	29	262	262	NUM
fnp-3025	349	30	]	]	PUNCT
fnp-3025	349	31	.	.	PUNCT
fnp-3025	350	1	figure	figure	NOUN
fnp-3025	350	2	15	15	NUM
fnp-3025	350	3	.	.	PUNCT
fnp-3025	351	1	fluorescence	fluorescence	NOUN
fnp-3025	351	2	-	-	PUNCT
fnp-3025	351	3	immunolabeled	immunolabele	VERB
fnp-3025	351	4	dyshoric	dyshoric	ADJ
fnp-3025	351	5	cerebral	cerebral	ADJ
fnp-3025	351	6	aβ	aβ	NOUN
fnp-3025	351	7	-	-	PUNCT
fnp-3025	351	8	amyloid	amyloid	NOUN
fnp-3025	351	9	angiopathy	angiopathy	NOUN
fnp-3025	351	10	(	(	PUNCT
fnp-3025	351	11	red	red	ADJ
fnp-3025	351	12	;	;	PUNCT
fnp-3025	351	13	antibody	antibody	NOUN
fnp-3025	351	14	r398	r398	PROPN
fnp-3025	351	15	)	)	PUNCT
fnp-3025	351	16	and	and	CCONJ
fnp-3025	351	17	tau	tau	PROPN
fnp-3025	351	18	-	-	PUNCT
fnp-3025	351	19	immunoreactive	immunoreactive	ADJ
fnp-3025	351	20	neurites	neurite	NOUN
fnp-3025	351	21	(	(	PUNCT
fnp-3025	351	22	green	green	ADJ
fnp-3025	351	23	;	;	PUNCT
fnp-3025	351	24	antibody	antibody	NOUN
fnp-3025	351	25	cp13	cp13	PROPN
fnp-3025	351	26	)	)	PUNCT
fnp-3025	351	27	in	in	ADP
fnp-3025	351	28	the	the	DET
fnp-3025	351	29	cortex	cortex	NOUN
fnp-3025	351	30	of	of	ADP
fnp-3025	351	31	an	an	DET
fnp-3025	351	32	ad	ad	NOUN
fnp-3025	351	33	patient	patient	NOUN
fnp-3025	351	34	.	.	PUNCT
fnp-3025	352	1	bar	bar	NOUN
fnp-3025	352	2	=	=	SYM
fnp-3025	352	3	50μm	50μm	NOUN
fnp-3025	352	4	.	.	PUNCT
fnp-3025	353	1	in	in	ADP
fnp-3025	353	2	the	the	DET
fnp-3025	353	3	early	early	ADJ
fnp-3025	353	4	stages	stage	NOUN
fnp-3025	353	5	of	of	ADP
fnp-3025	353	6	large	large	ADJ
fnp-3025	353	7	-	-	PUNCT
fnp-3025	353	8	vessel	vessel	NOUN
fnp-3025	353	9	aβ	aβ	NOUN
fnp-3025	353	10	-	-	PUNCT
fnp-3025	353	11	caa	caa	NOUN
fnp-3025	353	12	,	,	PUNCT
fnp-3025	353	13	aβ42	aβ42	PROPN
fnp-3025	353	14	is	be	AUX
fnp-3025	353	15	more	more	ADV
fnp-3025	353	16	commonly	commonly	ADV
fnp-3025	353	17	present	present	ADJ
fnp-3025	353	18	than	than	SCONJ
fnp-3025	353	19	is	be	AUX
fnp-3025	353	20	aβ40	aβ40	PROPN
fnp-3025	353	21	[	[	PUNCT
fnp-3025	353	22	263	263	NUM
fnp-3025	353	23	]	]	PUNCT
fnp-3025	353	24	,	,	PUNCT
fnp-3025	353	25	but	but	CCONJ
fnp-3025	353	26	in	in	ADP
fnp-3025	353	27	later	later	ADJ
fnp-3025	353	28	stages	stage	NOUN
fnp-3025	353	29	aβ40	aβ40	PROPN
fnp-3025	353	30	predominates	predominate	VERB
fnp-3025	353	31	[	[	X
fnp-3025	353	32	263	263	NUM
fnp-3025	353	33	,	,	PUNCT
fnp-3025	353	34	264	264	NUM
fnp-3025	353	35	]	]	PUNCT
fnp-3025	353	36	.	.	PUNCT
fnp-3025	354	1	capillary	capillary	ADJ
fnp-3025	354	2	aβ	aβ	NOUN
fnp-3025	354	3	-	-	PUNCT
fnp-3025	354	4	caa	caa	NOUN
fnp-3025	354	5	,	,	PUNCT
fnp-3025	354	6	however	however	ADV
fnp-3025	354	7	,	,	PUNCT
fnp-3025	354	8	more	more	ADV
fnp-3025	354	9	often	often	ADV
fnp-3025	354	10	is	be	AUX
fnp-3025	354	11	positive	positive	ADJ
fnp-3025	354	12	for	for	ADP
fnp-3025	354	13	aβ42	aβ42	PROPN
fnp-3025	354	14	than	than	ADP
fnp-3025	354	15	for	for	ADP
fnp-3025	354	16	aβ40	aβ40	PROPN
fnp-3025	354	17	[	[	PUNCT
fnp-3025	354	18	263	263	NUM
fnp-3025	354	19	]	]	PUNCT
fnp-3025	354	20	.	.	PUNCT
fnp-3025	355	1	it	it	PRON
fnp-3025	355	2	has	have	AUX
fnp-3025	355	3	been	be	AUX
fnp-3025	355	4	suggested	suggest	VERB
fnp-3025	355	5	that	that	SCONJ
fnp-3025	355	6	the	the	DET
fnp-3025	355	7	deposition	deposition	NOUN
fnp-3025	355	8	of	of	ADP
fnp-3025	355	9	aβ	aβ	PRON
fnp-3025	355	10	in	in	ADP
fnp-3025	355	11	capillaries	capillary	NOUN
fnp-3025	355	12	transpires	transpire	NOUN
fnp-3025	355	13	by	by	ADP
fnp-3025	355	14	a	a	DET
fnp-3025	355	15	different	different	ADJ
fnp-3025	355	16	mechanism	mechanism	NOUN
fnp-3025	355	17	than	than	ADP
fnp-3025	355	18	that	that	PRON
fnp-3025	355	19	in	in	ADP
fnp-3025	355	20	large	large	ADJ
fnp-3025	355	21	vessels	vessel	NOUN
fnp-3025	355	22	and	and	CCONJ
fnp-3025	355	23	aβ	aβ	PRON
fnp-3025	355	24	plaques	plaque	NOUN
fnp-3025	355	25	[	[	X
fnp-3025	355	26	25	25	NUM
fnp-3025	355	27	,	,	PUNCT
fnp-3025	355	28	26	26	NUM
fnp-3025	355	29	]	]	PUNCT
fnp-3025	355	30	.	.	PUNCT
fnp-3025	356	1	quantitative	quantitative	ADJ
fnp-3025	356	2	spatial	spatial	ADJ
fnp-3025	356	3	analysis	analysis	NOUN
fnp-3025	356	4	has	have	AUX
fnp-3025	356	5	largely	largely	ADV
fnp-3025	356	6	refuted	refute	VERB
fnp-3025	356	7	the	the	DET
fnp-3025	356	8	hypothesis	hypothesis	NOUN
fnp-3025	356	9	that	that	PRON
fnp-3025	356	10	cerebral	cerebral	ADJ
fnp-3025	356	11	capillaries	capillary	NOUN
fnp-3025	356	12	are	be	AUX
fnp-3025	356	13	the	the	DET
fnp-3025	356	14	nidus	nidus	PROPN
fnp-3025	356	15	of	of	ADP
fnp-3025	356	16	aβ	aβ	NOUN
fnp-3025	356	17	plaque	plaque	NOUN
fnp-3025	356	18	formation	formation	NOUN
fnp-3025	356	19	[	[	X
fnp-3025	356	20	265	265	NUM
fnp-3025	356	21	]	]	PUNCT
fnp-3025	356	22	.	.	PUNCT
fnp-3025	357	1	interestingly	interestingly	ADV
fnp-3025	357	2	,	,	PUNCT
fnp-3025	357	3	‘	'	PUNCT
fnp-3025	357	4	coarse	coarse	ADJ
fnp-3025	357	5	-	-	PUNCT
fnp-3025	357	6	grain	grain	NOUN
fnp-3025	357	7	’	'	PUNCT
fnp-3025	357	8	plaques	plaque	NOUN
fnp-3025	357	9	,	,	PUNCT
fnp-3025	357	10	a	a	DET
fnp-3025	357	11	special	special	ADJ
fnp-3025	357	12	type	type	NOUN
fnp-3025	357	13	of	of	ADP
fnp-3025	357	14	lesion	lesion	NOUN
fnp-3025	357	15	(	(	PUNCT
fnp-3025	357	16	see	see	VERB
fnp-3025	357	17	section	section	NOUN
fnp-3025	357	18	5.1	5.1	NUM
fnp-3025	357	19	)	)	PUNCT
fnp-3025	357	20	,	,	PUNCT
fnp-3025	357	21	are	be	AUX
fnp-3025	357	22	more	more	ADV
fnp-3025	357	23	common	common	ADJ
fnp-3025	357	24	in	in	ADP
fnp-3025	357	25	cases	case	NOUN
fnp-3025	357	26	with	with	ADP
fnp-3025	357	27	abundant	abundant	ADJ
fnp-3025	357	28	aβ	aβ	NOUN
fnp-3025	357	29	-	-	PUNCT
fnp-3025	357	30	caa	caa	NOUN
fnp-3025	357	31	,	,	PUNCT
fnp-3025	357	32	particularly	particularly	ADV
fnp-3025	357	33	capillary	capillary	ADJ
fnp-3025	357	34	aβ	aβ	NOUN
fnp-3025	357	35	-	-	PUNCT
fnp-3025	357	36	caa	caa	NOUN
fnp-3025	357	37	[	[	X
fnp-3025	357	38	179	179	NUM
fnp-3025	357	39	]	]	PUNCT
fnp-3025	357	40	.	.	PUNCT
fnp-3025	358	1	aβ	aβ	X
fnp-3025	358	2	-	-	PUNCT
fnp-3025	358	3	caa	caa	NOUN
fnp-3025	358	4	,	,	PUNCT
fnp-3025	358	5	like	like	ADP
fnp-3025	358	6	aβ	aβ	NOUN
fnp-3025	358	7	-	-	NOUN
fnp-3025	358	8	plaques	plaque	NOUN
fnp-3025	358	9	,	,	PUNCT
fnp-3025	358	10	is	be	AUX
fnp-3025	358	11	associated	associate	VERB
fnp-3025	358	12	with	with	ADP
fnp-3025	358	13	reactive	reactive	ADJ
fnp-3025	358	14	gliosis	gliosis	NOUN
fnp-3025	358	15	and	and	CCONJ
fnp-3025	358	16	a	a	DET
fnp-3025	358	17	perivascular	perivascular	ADJ
fnp-3025	358	18	inflammatory	inflammatory	ADJ
fnp-3025	358	19	response	response	NOUN
fnp-3025	358	20	[	[	X
fnp-3025	358	21	240	240	NUM
fnp-3025	358	22	,	,	PUNCT
fnp-3025	358	23	260	260	NUM
fnp-3025	358	24	]	]	PUNCT
fnp-3025	358	25	,	,	PUNCT
fnp-3025	358	26	although	although	SCONJ
fnp-3025	358	27	the	the	DET
fnp-3025	358	28	presence	presence	NOUN
fnp-3025	358	29	of	of	ADP
fnp-3025	358	30	frank	frank	ADJ
fnp-3025	358	31	perivascular	perivascular	ADJ
fnp-3025	358	32	inflammation	inflammation	NOUN
fnp-3025	358	33	is	be	AUX
fnp-3025	358	34	inconsistent	inconsistent	ADJ
fnp-3025	358	35	[	[	X
fnp-3025	358	36	25	25	NUM
fnp-3025	358	37	,	,	PUNCT
fnp-3025	358	38	266	266	NUM
fnp-3025	358	39	]	]	PUNCT
fnp-3025	358	40	.	.	PUNCT
fnp-3025	359	1	aβ	aβ	X
fnp-3025	359	2	-	-	PUNCT
fnp-3025	359	3	amyloid	amyloid	NOUN
fnp-3025	359	4	plaques	plaque	NOUN
fnp-3025	359	5	are	be	AUX
fnp-3025	359	6	occasionally	occasionally	ADV
fnp-3025	359	7	confluent	confluent	ADJ
fnp-3025	359	8	with	with	ADP
fnp-3025	359	9	aβ	aβ	NOUN
fnp-3025	359	10	-	-	PUNCT
fnp-3025	359	11	caa	caa	NOUN
fnp-3025	359	12	(	(	PUNCT
fnp-3025	359	13	‘	'	PUNCT
fnp-3025	359	14	juxtavascular	juxtavascular	ADJ
fnp-3025	359	15	plaques	plaque	NOUN
fnp-3025	359	16	’	'	PUNCT
fnp-3025	359	17	;	;	PUNCT
fnp-3025	359	18	figure	figure	VERB
fnp-3025	359	19	16	16	NUM
fnp-3025	359	20	)	)	PUNCT
fnp-3025	359	21	,	,	PUNCT
fnp-3025	359	22	but	but	CCONJ
fnp-3025	359	23	the	the	DET
fnp-3025	359	24	etiologic	etiologic	ADJ
fnp-3025	359	25	relationship	relationship	NOUN
fnp-3025	359	26	between	between	ADP
fnp-3025	359	27	these	these	DET
fnp-3025	359	28	merged	merge	VERB
fnp-3025	359	29	lesions	lesion	NOUN
fnp-3025	359	30	is	be	AUX
fnp-3025	359	31	uncertain	uncertain	ADJ
fnp-3025	359	32	.	.	PUNCT
fnp-3025	360	1	figure	figure	NOUN
fnp-3025	360	2	16	16	NUM
fnp-3025	360	3	.	.	PUNCT
fnp-3025	361	1	juxtavascular	juxtavascular	ADJ
fnp-3025	361	2	aβ	aβ	NOUN
fnp-3025	361	3	-	-	PUNCT
fnp-3025	361	4	plaque	plaque	NOUN
fnp-3025	361	5	(	(	PUNCT
fnp-3025	361	6	arrow	arrow	NOUN
fnp-3025	361	7	)	)	PUNCT
fnp-3025	361	8	in	in	ADP
fnp-3025	361	9	the	the	DET
fnp-3025	361	10	cortex	cortex	NOUN
fnp-3025	361	11	of	of	ADP
fnp-3025	361	12	an	an	DET
fnp-3025	361	13	ad	ad	NOUN
fnp-3025	361	14	patient	patient	NOUN
fnp-3025	361	15	.	.	PUNCT
fnp-3025	362	1	antibody	antibody	NOUN
fnp-3025	362	2	4g8	4g8	NUM
fnp-3025	362	3	,	,	PUNCT
fnp-3025	362	4	nissl	nissl	ADJ
fnp-3025	362	5	counterstain	counterstain	NOUN
fnp-3025	362	6	.	.	PUNCT
fnp-3025	363	1	bar	bar	NOUN
fnp-3025	363	2	=	=	SYM
fnp-3025	363	3	20μm	20μm	NOUN
fnp-3025	363	4	.	.	PUNCT
fnp-3025	364	1	various	various	ADJ
fnp-3025	364	2	genetic	genetic	ADJ
fnp-3025	364	3	,	,	PUNCT
fnp-3025	364	4	biochemical	biochemical	ADJ
fnp-3025	364	5	and	and	CCONJ
fnp-3025	364	6	pathophysiologic	pathophysiologic	ADJ
fnp-3025	364	7	factors	factor	NOUN
fnp-3025	364	8	appear	appear	VERB
fnp-3025	364	9	to	to	PART
fnp-3025	364	10	influence	influence	VERB
fnp-3025	364	11	how	how	SCONJ
fnp-3025	364	12	the	the	DET
fnp-3025	364	13	misfolding	misfolding	NOUN
fnp-3025	364	14	and	and	CCONJ
fnp-3025	364	15	aggregation	aggregation	NOUN
fnp-3025	364	16	of	of	ADP
fnp-3025	364	17	the	the	DET
fnp-3025	364	18	same	same	ADJ
fnp-3025	364	19	protein	protein	NOUN
fnp-3025	364	20	aβ	aβ	NOUN
fnp-3025	364	21	can	can	AUX
fnp-3025	364	22	lead	lead	VERB
fnp-3025	364	23	to	to	ADP
fnp-3025	364	24	two	two	NUM
fnp-3025	364	25	different	different	ADJ
fnp-3025	364	26	phenotypic	phenotypic	ADJ
fnp-3025	364	27	presentations	presentation	NOUN
fnp-3025	364	28	parenchymal	parenchymal	ADJ
fnp-3025	364	29	plaques	plaque	NOUN
fnp-3025	364	30	and	and	CCONJ
fnp-3025	364	31	vascular	vascular	ADJ
fnp-3025	364	32	amyloid	amyloid	NOUN
fnp-3025	365	1	[	[	X
fnp-3025	365	2	21	21	NUM
fnp-3025	365	3	]	]	PUNCT
fnp-3025	365	4	.	.	PUNCT
fnp-3025	366	1	while	while	SCONJ
fnp-3025	366	2	many	many	ADJ
fnp-3025	366	3	auxiliary	auxiliary	ADJ
fnp-3025	366	4	molecules	molecule	NOUN
fnp-3025	366	5	are	be	AUX
fnp-3025	366	6	present	present	ADJ
fnp-3025	366	7	in	in	ADP
fnp-3025	366	8	both	both	PRON
fnp-3025	366	9	aβ	aβ	ADP
fnp-3025	366	10	plaques	plaque	NOUN
fnp-3025	366	11	and	and	CCONJ
fnp-3025	366	12	aβ	aβ	NOUN
fnp-3025	366	13	-	-	PUNCT
fnp-3025	366	14	caa	caa	NOUN
fnp-3025	366	15	,	,	PUNCT
fnp-3025	366	16	some	some	PRON
fnp-3025	366	17	are	be	AUX
fnp-3025	366	18	not	not	PART
fnp-3025	366	19	shared	share	VERB
fnp-3025	366	20	by	by	ADP
fnp-3025	366	21	the	the	DET
fnp-3025	366	22	two	two	NUM
fnp-3025	366	23	lesions	lesion	NOUN
fnp-3025	366	24	[	[	X
fnp-3025	366	25	267	267	NUM
fnp-3025	366	26	]	]	PUNCT
fnp-3025	366	27	.	.	PUNCT
fnp-3025	367	1	thus	thus	ADV
fnp-3025	367	2	,	,	PUNCT
fnp-3025	367	3	aβ	aβ	PRON
fnp-3025	367	4	-	-	PUNCT
fnp-3025	367	5	caa	caa	NOUN
fnp-3025	367	6	and	and	CCONJ
fnp-3025	367	7	aβ	aβ	NOUN
fnp-3025	367	8	plaques	plaque	NOUN
fnp-3025	367	9	likely	likely	ADV
fnp-3025	367	10	result	result	VERB
fnp-3025	367	11	from	from	ADP
fnp-3025	367	12	at	at	ADV
fnp-3025	367	13	least	least	ADJ
fnp-3025	367	14	partially	partially	ADV
fnp-3025	367	15	distinct	distinct	ADJ
fnp-3025	367	16	ontogenetic	ontogenetic	ADJ
fnp-3025	367	17	pathways	pathway	NOUN
fnp-3025	367	18	[	[	X
fnp-3025	367	19	21	21	NUM
fnp-3025	367	20	]	]	X
fnp-3025	367	21	(	(	PUNCT
fnp-3025	367	22	in	in	ADP
fnp-3025	367	23	this	this	DET
fnp-3025	367	24	regard	regard	NOUN
fnp-3025	367	25	,	,	PUNCT
fnp-3025	367	26	it	it	PRON
fnp-3025	367	27	is	be	AUX
fnp-3025	367	28	noteworthy	noteworthy	ADJ
fnp-3025	367	29	that	that	SCONJ
fnp-3025	367	30	the	the	DET
fnp-3025	367	31	disappearance	disappearance	NOUN
fnp-3025	367	32	of	of	ADP
fnp-3025	367	33	plaques	plaque	NOUN
fnp-3025	367	34	in	in	ADP
fnp-3025	367	35	alzheimer	alzheimer	PROPN
fnp-3025	367	36	patients	patient	NOUN
fnp-3025	367	37	immunized	immunize	VERB
fnp-3025	367	38	against	against	ADP
fnp-3025	367	39	aβ	aβ	PRON
fnp-3025	367	40	is	be	AUX
fnp-3025	367	41	accompanied	accompany	VERB
fnp-3025	367	42	by	by	ADP
fnp-3025	367	43	a	a	DET
fnp-3025	367	44	[	[	X
fnp-3025	367	45	possibly	possibly	ADV
fnp-3025	367	46	transient	transient	NOUN
fnp-3025	367	47	]	]	PUNCT
fnp-3025	367	48	increase	increase	NOUN
fnp-3025	367	49	in	in	ADP
fnp-3025	367	50	aβ	aβ	NOUN
fnp-3025	367	51	-	-	PUNCT
fnp-3025	367	52	caa	caa	NOUN
fnp-3025	367	53	,	,	PUNCT
fnp-3025	367	54	suggesting	suggest	VERB
fnp-3025	367	55	a	a	DET
fnp-3025	367	56	transfer	transfer	NOUN
fnp-3025	367	57	of	of	ADP
fnp-3025	367	58	aβ	aβ	NOUN
fnp-3025	367	59	from	from	ADP
fnp-3025	367	60	the	the	DET
fnp-3025	367	61	parenchyma	parenchyma	NOUN
fnp-3025	367	62	to	to	ADP
fnp-3025	367	63	the	the	DET
fnp-3025	367	64	walls	wall	NOUN
fnp-3025	367	65	of	of	ADP
fnp-3025	367	66	blood	blood	NOUN
fnp-3025	367	67	vessels	vessel	NOUN
fnp-3025	367	68	[	[	X
fnp-3025	367	69	268	268	NUM
fnp-3025	367	70	]	]	PUNCT
fnp-3025	367	71	)	)	PUNCT
fnp-3025	367	72	.	.	PUNCT
fnp-3025	368	1	for	for	ADP
fnp-3025	368	2	in	in	ADP
fnp-3025	368	3	depth	depth	NOUN
fnp-3025	368	4	reviews	review	NOUN
fnp-3025	368	5	of	of	ADP
fnp-3025	368	6	caa	caa	NOUN
fnp-3025	368	7	,	,	PUNCT
fnp-3025	368	8	see	see	VERB
fnp-3025	368	9	[	[	X
fnp-3025	368	10	21	21	NUM
fnp-3025	368	11	,	,	PUNCT
fnp-3025	368	12	236	236	NUM
fnp-3025	368	13	,	,	PUNCT
fnp-3025	368	14	237	237	NUM
fnp-3025	368	15	,	,	PUNCT
fnp-3025	368	16	240	240	NUM
fnp-3025	368	17	,	,	PUNCT
fnp-3025	368	18	241	241	NUM
fnp-3025	368	19	,	,	PUNCT
fnp-3025	368	20	260	260	NUM
fnp-3025	368	21	,	,	PUNCT
fnp-3025	368	22	269	269	NUM
fnp-3025	368	23	]	]	PUNCT
fnp-3025	368	24	.	.	PUNCT
fnp-3025	369	1	6	6	X
fnp-3025	369	2	.	.	X
fnp-3025	369	3	cellular	cellular	ADJ
fnp-3025	369	4	components	component	NOUN
fnp-3025	369	5	of	of	ADP
fnp-3025	369	6	aβ	aβ	NOUN
fnp-3025	369	7	plaques	plaque	NOUN
fnp-3025	369	8	the	the	DET
fnp-3025	369	9	main	main	ADJ
fnp-3025	369	10	cellular	cellular	ADJ
fnp-3025	369	11	elements	element	NOUN
fnp-3025	369	12	neuronal	neuronal	ADJ
fnp-3025	369	13	processes	process	NOUN
fnp-3025	369	14	and	and	CCONJ
fnp-3025	369	15	glial	glial	ADJ
fnp-3025	369	16	cells	cell	NOUN
fnp-3025	369	17	in	in	ADP
fnp-3025	369	18	classical	classical	ADJ
fnp-3025	369	19	plaques	plaque	NOUN
fnp-3025	369	20	were	be	AUX
fnp-3025	369	21	well	well	ADV
fnp-3025	369	22	-	-	PUNCT
fnp-3025	369	23	documented	document	VERB
fnp-3025	369	24	by	by	ADP
fnp-3025	369	25	pioneering	pioneer	VERB
fnp-3025	369	26	investigators	investigator	NOUN
fnp-3025	369	27	in	in	ADP
fnp-3025	369	28	the	the	DET
fnp-3025	369	29	field	field	NOUN
fnp-3025	369	30	(	(	PUNCT
fnp-3025	369	31	see	see	VERB
fnp-3025	369	32	[	[	X
fnp-3025	369	33	116]),12	116]),12	NUM
fnp-3025	369	34	although	although	SCONJ
fnp-3025	369	35	the	the	DET
fnp-3025	369	36	nature	nature	NOUN
fnp-3025	369	37	of	of	ADP
fnp-3025	369	38	their	their	PRON
fnp-3025	369	39	involvement	involvement	NOUN
fnp-3025	369	40	,	,	PUNCT
fnp-3025	369	41	and	and	CCONJ
fnp-3025	369	42	their	their	PRON
fnp-3025	369	43	functional	functional	ADJ
fnp-3025	369	44	relationship	relationship	NOUN
fnp-3025	369	45	to	to	ADP
fnp-3025	369	46	the	the	DET
fnp-3025	369	47	core	core	NOUN
fnp-3025	369	48	,	,	PUNCT
fnp-3025	369	49	have	have	AUX
fnp-3025	369	50	been	be	AUX
fnp-3025	369	51	a	a	DET
fnp-3025	369	52	persistent	persistent	ADJ
fnp-3025	369	53	matter	matter	NOUN
fnp-3025	369	54	of	of	ADP
fnp-3025	369	55	speculation	speculation	NOUN
fnp-3025	369	56	[	[	X
fnp-3025	369	57	207	207	NUM
fnp-3025	369	58	]	]	PUNCT
fnp-3025	369	59	.	.	PUNCT
fnp-3025	370	1	diffuse	diffuse	VERB
fnp-3025	370	2	deposits	deposit	NOUN
fnp-3025	370	3	of	of	ADP
fnp-3025	370	4	aβ	aβ	PRON
fnp-3025	370	5	mostly	mostly	ADV
fnp-3025	370	6	lack	lack	VERB
fnp-3025	370	7	obvious	obvious	ADJ
fnp-3025	370	8	changes	change	NOUN
fnp-3025	370	9	in	in	ADP
fnp-3025	370	10	local	local	ADJ
fnp-3025	370	11	neurons	neuron	NOUN
fnp-3025	370	12	and	and	CCONJ
fnp-3025	370	13	glial	glial	ADJ
fnp-3025	370	14	cells	cell	NOUN
fnp-3025	370	15	,	,	PUNCT
fnp-3025	370	16	whereas	whereas	SCONJ
fnp-3025	370	17	these	these	DET
fnp-3025	370	18	cells	cell	NOUN
fnp-3025	370	19	are	be	AUX
fnp-3025	370	20	conspicuously	conspicuously	ADV
fnp-3025	370	21	altered	alter	VERB
fnp-3025	370	22	in	in	ADP
fnp-3025	370	23	classical	classical	ADJ
fnp-3025	370	24	aβ	aβ	NOUN
fnp-3025	370	25	plaques	plaque	NOUN
fnp-3025	370	26	.	.	PUNCT
fnp-3025	371	1	since	since	SCONJ
fnp-3025	371	2	classical	classical	ADJ
fnp-3025	371	3	plaques	plaque	NOUN
fnp-3025	371	4	are	be	AUX
fnp-3025	371	5	especially	especially	ADV
fnp-3025	371	6	numerous	numerous	ADJ
fnp-3025	371	7	in	in	ADP
fnp-3025	371	8	most	most	ADJ
fnp-3025	371	9	cases	case	NOUN
fnp-3025	371	10	of	of	ADP
fnp-3025	371	11	late	late	ADJ
fnp-3025	371	12	-	-	PUNCT
fnp-3025	371	13	stage	stage	NOUN
fnp-3025	371	14	ad	ad	NOUN
fnp-3025	371	15	,	,	PUNCT
fnp-3025	371	16	the	the	DET
fnp-3025	371	17	associated	associated	ADJ
fnp-3025	371	18	abnormal	abnormal	ADJ
fnp-3025	371	19	neurites	neurite	NOUN
fnp-3025	371	20	and	and	CCONJ
fnp-3025	371	21	activated	activate	VERB
fnp-3025	371	22	glial	glial	ADJ
fnp-3025	371	23	cells	cell	NOUN
fnp-3025	371	24	probably	probably	ADV
fnp-3025	371	25	contribute	contribute	VERB
fnp-3025	371	26	to	to	ADP
fnp-3025	371	27	the	the	DET
fnp-3025	371	28	disturbance	disturbance	NOUN
fnp-3025	371	29	of	of	ADP
fnp-3025	371	30	brain	brain	NOUN
fnp-3025	371	31	function	function	NOUN
fnp-3025	371	32	by	by	ADP
fnp-3025	371	33	the	the	DET
fnp-3025	371	34	plaques	plaque	NOUN
fnp-3025	371	35	[	[	X
fnp-3025	371	36	133	133	NUM
fnp-3025	371	37	]	]	PUNCT
fnp-3025	371	38	.	.	PUNCT
fnp-3025	372	1	12	12	NUM
fnp-3025	372	2	early	early	ADJ
fnp-3025	372	3	descriptions	description	NOUN
fnp-3025	372	4	of	of	ADP
fnp-3025	372	5	plaques	plaque	NOUN
fnp-3025	372	6	included	include	VERB
fnp-3025	372	7	drawings	drawing	NOUN
fnp-3025	372	8	that	that	PRON
fnp-3025	372	9	enabled	enable	VERB
fnp-3025	372	10	the	the	DET
fnp-3025	372	11	artist	artist	NOUN
fnp-3025	372	12	to	to	PART
fnp-3025	372	13	clearly	clearly	ADV
fnp-3025	372	14	depict	depict	VERB
fnp-3025	372	15	all	all	DET
fnp-3025	372	16	cellular	cellular	ADJ
fnp-3025	372	17	elements	element	NOUN
fnp-3025	372	18	throughout	throughout	ADP
fnp-3025	372	19	the	the	DET
fnp-3025	372	20	depth	depth	NOUN
fnp-3025	372	21	of	of	ADP
fnp-3025	372	22	the	the	DET
fnp-3025	372	23	tissue	tissue	NOUN
fnp-3025	372	24	sections	section	NOUN
fnp-3025	372	25	in	in	ADP
fnp-3025	372	26	a	a	DET
fnp-3025	372	27	way	way	NOUN
fnp-3025	372	28	that	that	PRON
fnp-3025	372	29	photomicrography	photomicrography	NOUN
fnp-3025	372	30	,	,	PUNCT
fnp-3025	372	31	still	still	ADV
fnp-3025	372	32	in	in	ADP
fnp-3025	372	33	its	its	PRON
fnp-3025	372	34	infancy	infancy	NOUN
fnp-3025	372	35	,	,	PUNCT
fnp-3025	372	36	could	could	AUX
fnp-3025	372	37	not	not	PART
fnp-3025	372	38	.	.	PUNCT
fnp-3025	373	1	the	the	DET
fnp-3025	373	2	result	result	NOUN
fnp-3025	373	3	was	be	AUX
fnp-3025	373	4	sometimes	sometimes	ADV
fnp-3025	373	5	striking	strike	VERB
fnp-3025	373	6	images	image	NOUN
fnp-3025	373	7	that	that	PRON
fnp-3025	373	8	have	have	AUX
fnp-3025	373	9	been	be	AUX
fnp-3025	373	10	difficult	difficult	ADJ
fnp-3025	373	11	to	to	PART
fnp-3025	373	12	surpass	surpass	VERB
fnp-3025	373	13	in	in	ADP
fnp-3025	373	14	the	the	DET
fnp-3025	373	15	century	century	NOUN
fnp-3025	373	16	-	-	PUNCT
fnp-3025	373	17	plus	plus	CCONJ
fnp-3025	373	18	since	since	SCONJ
fnp-3025	373	19	(	(	PUNCT
fnp-3025	373	20	see	see	VERB
fnp-3025	373	21	,	,	PUNCT
fnp-3025	373	22	e.g.	e.g.	ADV
fnp-3025	373	23	,	,	PUNCT
fnp-3025	373	24	the	the	DET
fnp-3025	373	25	fine	fine	ADJ
fnp-3025	373	26	reproductions	reproduction	NOUN
fnp-3025	373	27	in	in	ADP
fnp-3025	373	28	defelipe	defelipe	NOUN
fnp-3025	373	29	[	[	X
fnp-3025	373	30	2010	2010	NUM
fnp-3025	373	31	]	]	PUNCT
fnp-3025	374	1	[	[	X
fnp-3025	374	2	reference	reference	NOUN
fnp-3025	374	3	510	510	NUM
fnp-3025	374	4	]	]	PUNCT
fnp-3025	374	5	)	)	PUNCT
fnp-3025	374	6	.	.	PUNCT
fnp-3025	375	1	6.1	6.1	NUM
fnp-3025	375	2	.	.	X
fnp-3025	375	3	abnormal	abnormal	ADJ
fnp-3025	375	4	neurites	neurite	NOUN
fnp-3025	375	5	in	in	ADP
fnp-3025	375	6	advanced	advanced	ADJ
fnp-3025	375	7	ad	ad	NOUN
fnp-3025	375	8	,	,	PUNCT
fnp-3025	375	9	many	many	ADJ
fnp-3025	375	10	aβ	aβ	NOUN
fnp-3025	375	11	plaques	plaque	NOUN
fnp-3025	375	12	are	be	AUX
fnp-3025	375	13	decorated	decorate	VERB
fnp-3025	375	14	with	with	ADP
fnp-3025	375	15	an	an	DET
fnp-3025	375	16	impressive	impressive	ADJ
fnp-3025	375	17	profusion	profusion	NOUN
fnp-3025	375	18	of	of	ADP
fnp-3025	375	19	dysmorphic	dysmorphic	ADJ
fnp-3025	375	20	neurites	neurite	NOUN
fnp-3025	375	21	(	(	PUNCT
fnp-3025	375	22	figures	figure	NOUN
fnp-3025	375	23	1	1	NUM
fnp-3025	375	24	,	,	PUNCT
fnp-3025	375	25	4	4	NUM
fnp-3025	375	26	,	,	PUNCT
fnp-3025	375	27	17	17	NUM
fnp-3025	375	28	)	)	PUNCT
fnp-3025	375	29	.	.	PUNCT
fnp-3025	376	1	both	both	DET
fnp-3025	376	2	axons	axon	NOUN
fnp-3025	376	3	and	and	CCONJ
fnp-3025	376	4	dendrites	dendrite	NOUN
fnp-3025	376	5	contribute	contribute	VERB
fnp-3025	376	6	neurites	neurite	NOUN
fnp-3025	376	7	to	to	ADP
fnp-3025	376	8	plaques	plaque	NOUN
fnp-3025	376	9	[	[	X
fnp-3025	376	10	207	207	NUM
fnp-3025	376	11	,	,	PUNCT
fnp-3025	376	12	270	270	NUM
fnp-3025	376	13	]	]	PUNCT
fnp-3025	376	14	.	.	PUNCT
fnp-3025	377	1	although	although	SCONJ
fnp-3025	377	2	most	most	ADJ
fnp-3025	377	3	swollen	swollen	ADJ
fnp-3025	377	4	neurites	neurite	NOUN
fnp-3025	377	5	have	have	AUX
fnp-3025	377	6	been	be	AUX
fnp-3025	377	7	reported	report	VERB
fnp-3025	377	8	to	to	PART
fnp-3025	377	9	be	be	AUX
fnp-3025	377	10	axonal	axonal	ADJ
fnp-3025	377	11	in	in	ADP
fnp-3025	377	12	origin	origin	NOUN
fnp-3025	377	13	[	[	X
fnp-3025	377	14	138	138	NUM
fnp-3025	377	15	,	,	PUNCT
fnp-3025	377	16	178	178	NUM
fnp-3025	377	17	,	,	PUNCT
fnp-3025	377	18	207	207	NUM
fnp-3025	377	19	]	]	PUNCT
fnp-3025	377	20	,	,	PUNCT
fnp-3025	377	21	a	a	DET
fnp-3025	377	22	quantitative	quantitative	ADJ
fnp-3025	377	23	analysis	analysis	NOUN
fnp-3025	377	24	of	of	ADP
fnp-3025	377	25	plaques	plaque	NOUN
fnp-3025	377	26	in	in	ADP
fnp-3025	377	27	humans	human	NOUN
fnp-3025	377	28	using	use	VERB
fnp-3025	377	29	axonand	axonand	ADJ
fnp-3025	377	30	dendrite	dendrite	ADJ
fnp-3025	377	31	-	-	PUNCT
fnp-3025	377	32	specific	specific	ADJ
fnp-3025	377	33	markers	marker	NOUN
fnp-3025	377	34	is	be	AUX
fnp-3025	377	35	needed	need	VERB
fnp-3025	377	36	to	to	PART
fnp-3025	377	37	establish	establish	VERB
fnp-3025	377	38	the	the	DET
fnp-3025	377	39	relative	relative	ADJ
fnp-3025	377	40	involvement	involvement	NOUN
fnp-3025	377	41	of	of	ADP
fnp-3025	377	42	these	these	DET
fnp-3025	377	43	neuronal	neuronal	ADJ
fnp-3025	377	44	processes	process	NOUN
fnp-3025	377	45	.	.	PUNCT
fnp-3025	378	1	tortuous	tortuous	ADJ
fnp-3025	378	2	,	,	PUNCT
fnp-3025	378	3	atypical	atypical	ADJ
fnp-3025	378	4	neurites	neurite	NOUN
fnp-3025	378	5	that	that	PRON
fnp-3025	378	6	are	be	AUX
fnp-3025	378	7	not	not	PART
fnp-3025	378	8	spatially	spatially	ADV
fnp-3025	378	9	associated	associate	VERB
fnp-3025	378	10	with	with	ADP
fnp-3025	378	11	plaques	plaque	NOUN
fnp-3025	378	12	are	be	AUX
fnp-3025	378	13	fairly	fairly	ADV
fnp-3025	378	14	common	common	ADJ
fnp-3025	378	15	in	in	ADP
fnp-3025	378	16	the	the	DET
fnp-3025	378	17	aging	age	VERB
fnp-3025	378	18	brain	brain	NOUN
fnp-3025	378	19	[	[	X
fnp-3025	378	20	139	139	NUM
fnp-3025	378	21	]	]	PUNCT
fnp-3025	378	22	,	,	PUNCT
fnp-3025	378	23	but	but	CCONJ
fnp-3025	378	24	neuritic	neuritic	ADJ
fnp-3025	378	25	pathology	pathology	NOUN
fnp-3025	378	26	is	be	AUX
fnp-3025	378	27	particularly	particularly	ADV
fnp-3025	378	28	evident	evident	ADJ
fnp-3025	378	29	in	in	ADP
fnp-3025	378	30	many	many	ADJ
fnp-3025	378	31	aβ	aβ	NOUN
fnp-3025	378	32	-	-	PUNCT
fnp-3025	378	33	amyloid	amyloid	NOUN
fnp-3025	378	34	plaques	plaque	NOUN
fnp-3025	378	35	.	.	PUNCT
fnp-3025	379	1	by	by	ADP
fnp-3025	379	2	disrupting	disrupt	VERB
fnp-3025	379	3	the	the	DET
fnp-3025	379	4	structure	structure	NOUN
fnp-3025	379	5	and	and	CCONJ
fnp-3025	379	6	trajectory	trajectory	NOUN
fnp-3025	379	7	of	of	ADP
fnp-3025	379	8	neuronal	neuronal	ADJ
fnp-3025	379	9	processes	process	NOUN
fnp-3025	379	10	,	,	PUNCT
fnp-3025	379	11	aβ	aβ	DET
fnp-3025	379	12	plaques	plaque	NOUN
fnp-3025	379	13	are	be	AUX
fnp-3025	379	14	thought	think	VERB
fnp-3025	379	15	to	to	PART
fnp-3025	379	16	interfere	interfere	VERB
fnp-3025	379	17	with	with	ADP
fnp-3025	379	18	the	the	DET
fnp-3025	379	19	connectivity	connectivity	NOUN
fnp-3025	379	20	and	and	CCONJ
fnp-3025	379	21	network	network	NOUN
fnp-3025	379	22	functionality	functionality	NOUN
fnp-3025	379	23	of	of	ADP
fnp-3025	379	24	the	the	DET
fnp-3025	379	25	brain	brain	NOUN
fnp-3025	380	1	[	[	X
fnp-3025	380	2	38	38	NUM
fnp-3025	380	3	]	]	PUNCT
fnp-3025	380	4	.	.	PUNCT
fnp-3025	381	1	figure	figure	NOUN
fnp-3025	381	2	17	17	NUM
fnp-3025	381	3	.	.	PUNCT
fnp-3025	382	1	abnormal	abnormal	ADJ
fnp-3025	382	2	neurites	neurite	NOUN
fnp-3025	382	3	associated	associate	VERB
fnp-3025	382	4	with	with	ADP
fnp-3025	382	5	cortical	cortical	ADJ
fnp-3025	382	6	aβ	aβ	NOUN
fnp-3025	382	7	plaques	plaque	NOUN
fnp-3025	382	8	in	in	ADP
fnp-3025	382	9	two	two	NUM
fnp-3025	382	10	ad	ad	NOUN
fnp-3025	382	11	patients	patient	NOUN
fnp-3025	382	12	.	.	PUNCT
fnp-3025	383	1	left	leave	VERB
fnp-3025	383	2	:	:	PUNCT
fnp-3025	383	3	immunostain	immunostain	VERB
fnp-3025	383	4	for	for	ADP
fnp-3025	383	5	neurofilament	neurofilament	NOUN
fnp-3025	383	6	-	-	PUNCT
fnp-3025	383	7	h	h	NOUN
fnp-3025	383	8	(	(	PUNCT
fnp-3025	383	9	antibody	antibody	NOUN
fnp-3025	383	10	smi31	smi31	NOUN
fnp-3025	383	11	)	)	PUNCT
fnp-3025	383	12	with	with	ADP
fnp-3025	383	13	a	a	DET
fnp-3025	383	14	nissl	nissl	ADJ
fnp-3025	383	15	counterstain	counterstain	NOUN
fnp-3025	383	16	;	;	PUNCT
fnp-3025	383	17	right	right	ADJ
fnp-3025	383	18	,	,	PUNCT
fnp-3025	383	19	immunostain	immunostain	VERB
fnp-3025	383	20	for	for	ADP
fnp-3025	383	21	a	a	DET
fnp-3025	383	22	conformational	conformational	ADJ
fnp-3025	383	23	epitope	epitope	NOUN
fnp-3025	383	24	on	on	ADP
fnp-3025	383	25	tau	tau	PROPN
fnp-3025	383	26	filaments	filament	NOUN
fnp-3025	383	27	(	(	PUNCT
fnp-3025	383	28	antibody	antibody	NOUN
fnp-3025	383	29	mc1	mc1	PROPN
fnp-3025	383	30	)	)	PUNCT
fnp-3025	383	31	.	.	PUNCT
fnp-3025	384	1	the	the	DET
fnp-3025	384	2	presence	presence	NOUN
fnp-3025	384	3	of	of	ADP
fnp-3025	384	4	aberrant	aberrant	ADJ
fnp-3025	384	5	neurites	neurite	NOUN
fnp-3025	384	6	that	that	PRON
fnp-3025	384	7	are	be	AUX
fnp-3025	384	8	immunoreactive	immunoreactive	ADJ
fnp-3025	384	9	for	for	ADP
fnp-3025	384	10	these	these	DET
fnp-3025	384	11	antigens	antigen	NOUN
fnp-3025	384	12	in	in	ADP
fnp-3025	384	13	plaques	plaque	NOUN
fnp-3025	384	14	is	be	AUX
fnp-3025	384	15	variable	variable	ADJ
fnp-3025	384	16	.	.	PUNCT
fnp-3025	385	1	bar	bar	NOUN
fnp-3025	385	2	=	=	SYM
fnp-3025	385	3	25μm	25μm	ADJ
fnp-3025	385	4	(	(	PUNCT
fnp-3025	385	5	right	right	NOUN
fnp-3025	385	6	)	)	PUNCT
fnp-3025	385	7	and	and	CCONJ
fnp-3025	385	8	50μm	50μm	ADJ
fnp-3025	385	9	(	(	PUNCT
fnp-3025	385	10	left	leave	VERB
fnp-3025	385	11	)	)	PUNCT
fnp-3025	385	12	.	.	PUNCT
fnp-3025	386	1	abnormal	abnormal	ADJ
fnp-3025	386	2	neurites	neurite	NOUN
fnp-3025	386	3	are	be	AUX
fnp-3025	386	4	heterogeneous	heterogeneous	ADJ
fnp-3025	386	5	in	in	ADP
fnp-3025	386	6	size	size	NOUN
fnp-3025	386	7	,	,	PUNCT
fnp-3025	386	8	shape	shape	NOUN
fnp-3025	386	9	and	and	CCONJ
fnp-3025	386	10	content	content	NOUN
fnp-3025	386	11	.	.	PUNCT
fnp-3025	387	1	ultrastructurally	ultrastructurally	ADV
fnp-3025	387	2	,	,	PUNCT
fnp-3025	387	3	plaque	plaque	NOUN
fnp-3025	387	4	-	-	PUNCT
fnp-3025	387	5	associated	associate	VERB
fnp-3025	387	6	neurites	neurite	NOUN
fnp-3025	387	7	may	may	AUX
fnp-3025	387	8	contain	contain	VERB
fnp-3025	387	9	any	any	PRON
fnp-3025	387	10	of	of	ADP
fnp-3025	387	11	a	a	DET
fnp-3025	387	12	number	number	NOUN
fnp-3025	387	13	of	of	ADP
fnp-3025	387	14	inclusions	inclusion	NOUN
fnp-3025	387	15	,	,	PUNCT
fnp-3025	387	16	including	include	VERB
fnp-3025	387	17	,	,	PUNCT
fnp-3025	387	18	in	in	ADP
fnp-3025	387	19	addition	addition	NOUN
fnp-3025	387	20	to	to	ADP
fnp-3025	387	21	paired	pair	VERB
fnp-3025	387	22	helical	helical	ADJ
fnp-3025	387	23	filaments	filament	NOUN
fnp-3025	387	24	,	,	PUNCT
fnp-3025	387	25	profuse	profuse	NOUN
fnp-3025	387	26	mitochondria	mitochondria	PROPN
fnp-3025	387	27	,	,	PUNCT
fnp-3025	387	28	various	various	ADJ
fnp-3025	387	29	dense	dense	ADJ
fnp-3025	387	30	bodies	body	NOUN
fnp-3025	387	31	,	,	PUNCT
fnp-3025	387	32	membranes	membrane	NOUN
fnp-3025	387	33	,	,	PUNCT
fnp-3025	387	34	and	and	CCONJ
fnp-3025	387	35	multivesicular	multivesicular	ADJ
fnp-3025	387	36	profiles	profile	NOUN
fnp-3025	387	37	[	[	X
fnp-3025	387	38	139	139	NUM
fnp-3025	387	39	,	,	PUNCT
fnp-3025	387	40	178	178	NUM
fnp-3025	387	41	]	]	PUNCT
fnp-3025	387	42	(	(	PUNCT
fnp-3025	387	43	figure	figure	NOUN
fnp-3025	387	44	18	18	NUM
fnp-3025	387	45	)	)	PUNCT
fnp-3025	387	46	.	.	PUNCT
fnp-3025	388	1	the	the	DET
fnp-3025	388	2	mitochondria	mitochondria	PROPN
fnp-3025	388	3	appear	appear	VERB
fnp-3025	388	4	to	to	PART
fnp-3025	388	5	be	be	AUX
fnp-3025	388	6	in	in	ADP
fnp-3025	388	7	different	different	ADJ
fnp-3025	388	8	stages	stage	NOUN
fnp-3025	388	9	of	of	ADP
fnp-3025	388	10	degeneration	degeneration	NOUN
fnp-3025	388	11	,	,	PUNCT
fnp-3025	388	12	and	and	CCONJ
fnp-3025	388	13	they	they	PRON
fnp-3025	388	14	have	have	AUX
fnp-3025	388	15	been	be	AUX
fnp-3025	388	16	hypothesized	hypothesize	VERB
fnp-3025	388	17	to	to	PART
fnp-3025	388	18	be	be	AUX
fnp-3025	388	19	a	a	DET
fnp-3025	388	20	source	source	NOUN
fnp-3025	388	21	of	of	ADP
fnp-3025	388	22	the	the	DET
fnp-3025	388	23	aβ	aβ	NOUN
fnp-3025	388	24	-	-	PUNCT
fnp-3025	388	25	amyloid	amyloid	NOUN
fnp-3025	388	26	in	in	ADP
fnp-3025	388	27	plaques	plaque	NOUN
fnp-3025	388	28	[	[	X
fnp-3025	388	29	207	207	NUM
fnp-3025	388	30	]	]	PUNCT
fnp-3025	388	31	,	,	PUNCT
fnp-3025	388	32	as	as	SCONJ
fnp-3025	388	33	have	have	VERB
fnp-3025	388	34	multivesicular	multivesicular	ADJ
fnp-3025	388	35	bodies	body	NOUN
fnp-3025	388	36	[	[	X
fnp-3025	388	37	199	199	NUM
fnp-3025	388	38	,	,	PUNCT
fnp-3025	388	39	271	271	NUM
fnp-3025	388	40	,	,	PUNCT
fnp-3025	388	41	272	272	NUM
fnp-3025	388	42	]	]	PUNCT
fnp-3025	388	43	.	.	PUNCT
fnp-3025	389	1	the	the	DET
fnp-3025	389	2	cytoskeleton	cytoskeleton	PROPN
fnp-3025	389	3	is	be	AUX
fnp-3025	389	4	disrupted	disrupt	VERB
fnp-3025	389	5	in	in	ADP
fnp-3025	389	6	swollen	swollen	ADJ
fnp-3025	389	7	neurites	neurite	NOUN
fnp-3025	389	8	[	[	X
fnp-3025	389	9	273	273	NUM
fnp-3025	389	10	]	]	PUNCT
fnp-3025	389	11	,	,	PUNCT
fnp-3025	389	12	and	and	CCONJ
fnp-3025	389	13	studies	study	NOUN
fnp-3025	389	14	of	of	ADP
fnp-3025	389	15	mouse	mouse	NOUN
fnp-3025	389	16	models	model	NOUN
fnp-3025	389	17	found	find	VERB
fnp-3025	389	18	that	that	SCONJ
fnp-3025	389	19	neuritic	neuritic	ADJ
fnp-3025	389	20	calcium	calcium	NOUN
fnp-3025	389	21	(	(	PUNCT
fnp-3025	389	22	ca2	ca2	PROPN
fnp-3025	389	23	+	+	NOUN
fnp-3025	389	24	)	)	PUNCT
fnp-3025	389	25	homeostasis	homeostasis	NOUN
fnp-3025	389	26	[	[	X
fnp-3025	389	27	274	274	NUM
fnp-3025	389	28	]	]	PUNCT
fnp-3025	389	29	and	and	CCONJ
fnp-3025	389	30	autophagy	autophagy	NOUN
fnp-3025	390	1	[	[	X
fnp-3025	390	2	275	275	NUM
fnp-3025	390	3	]	]	PUNCT
fnp-3025	390	4	are	be	AUX
fnp-3025	390	5	dysregulated	dysregulate	VERB
fnp-3025	390	6	in	in	ADP
fnp-3025	390	7	them	they	PRON
fnp-3025	390	8	.	.	PUNCT
fnp-3025	391	1	dickson	dickson	PROPN
fnp-3025	392	1	[	[	X
fnp-3025	392	2	139	139	NUM
fnp-3025	392	3	]	]	X
fnp-3025	392	4	divided	divide	VERB
fnp-3025	392	5	abnormal	abnormal	ADJ
fnp-3025	392	6	neurites	neurite	NOUN
fnp-3025	392	7	into	into	ADP
fnp-3025	392	8	paired	pair	VERB
fnp-3025	392	9	helical	helical	ADJ
fnp-3025	392	10	filament	filament	NOUN
fnp-3025	392	11	(	(	PUNCT
fnp-3025	392	12	phf)-type	phf)-type	PROPN
fnp-3025	392	13	neurites	neurite	NOUN
fnp-3025	392	14	,	,	PUNCT
fnp-3025	392	15	which	which	PRON
fnp-3025	392	16	are	be	AUX
fnp-3025	392	17	characteristic	characteristic	ADJ
fnp-3025	392	18	of	of	ADP
fnp-3025	392	19	advanced	advanced	ADJ
fnp-3025	392	20	ad	ad	NOUN
fnp-3025	392	21	,	,	PUNCT
fnp-3025	392	22	and	and	CCONJ
fnp-3025	392	23	dystrophic	dystrophic	ADJ
fnp-3025	392	24	-	-	PUNCT
fnp-3025	392	25	type	type	NOUN
fnp-3025	392	26	neurites	neurite	NOUN
fnp-3025	392	27	,	,	PUNCT
fnp-3025	392	28	which	which	PRON
fnp-3025	392	29	are	be	AUX
fnp-3025	392	30	relatively	relatively	ADV
fnp-3025	392	31	more	more	ADV
fnp-3025	392	32	frequent	frequent	ADJ
fnp-3025	392	33	in	in	ADP
fnp-3025	392	34	the	the	DET
fnp-3025	392	35	plaques	plaque	NOUN
fnp-3025	392	36	found	find	VERB
fnp-3025	392	37	in	in	ADP
fnp-3025	392	38	aged	aged	ADJ
fnp-3025	392	39	,	,	PUNCT
fnp-3025	392	40	non	non	ADJ
fnp-3025	392	41	-	-	ADJ
fnp-3025	392	42	demented	demented	ADJ
fnp-3025	392	43	subjects	subject	NOUN
fnp-3025	392	44	(	(	PUNCT
fnp-3025	392	45	and	and	CCONJ
fnp-3025	392	46	in	in	ADP
fnp-3025	392	47	animal	animal	NOUN
fnp-3025	392	48	models	model	NOUN
fnp-3025	392	49	,	,	PUNCT
fnp-3025	392	50	in	in	ADP
fnp-3025	392	51	which	which	PRON
fnp-3025	392	52	phfs	phfs	NOUN
fnp-3025	392	53	per	per	X
fnp-3025	392	54	se	se	X
fnp-3025	392	55	are	be	AUX
fnp-3025	392	56	rare	rare	ADJ
fnp-3025	392	57	or	or	CCONJ
fnp-3025	392	58	absent	absent	ADJ
fnp-3025	392	59	[	[	PUNCT
fnp-3025	392	60	165	165	NUM
fnp-3025	392	61	]	]	PUNCT
fnp-3025	392	62	;	;	PUNCT
fnp-3025	392	63	see	see	VERB
fnp-3025	392	64	section	section	NOUN
fnp-3025	392	65	10	10	NUM
fnp-3025	392	66	)	)	PUNCT
fnp-3025	392	67	.	.	PUNCT
fnp-3025	393	1	dickson	dickson	PROPN
fnp-3025	393	2	also	also	ADV
fnp-3025	393	3	notes	note	VERB
fnp-3025	393	4	,	,	PUNCT
fnp-3025	393	5	however	however	ADV
fnp-3025	393	6	,	,	PUNCT
fnp-3025	393	7	that	that	SCONJ
fnp-3025	393	8	many	many	ADJ
fnp-3025	393	9	neurites	neurite	NOUN
fnp-3025	393	10	have	have	VERB
fnp-3025	393	11	the	the	DET
fnp-3025	393	12	properties	property	NOUN
fnp-3025	393	13	of	of	ADP
fnp-3025	393	14	both	both	DET
fnp-3025	393	15	types	type	NOUN
fnp-3025	393	16	,	,	PUNCT
fnp-3025	393	17	and	and	CCONJ
fnp-3025	393	18	that	that	SCONJ
fnp-3025	393	19	abnormal	abnormal	ADJ
fnp-3025	393	20	neurites	neurite	NOUN
fnp-3025	393	21	tend	tend	VERB
fnp-3025	393	22	to	to	PART
fnp-3025	393	23	arise	arise	VERB
fnp-3025	393	24	from	from	ADP
fnp-3025	393	25	axons	axon	NOUN
fnp-3025	393	26	or	or	CCONJ
fnp-3025	393	27	dendrites	dendrite	NOUN
fnp-3025	393	28	that	that	PRON
fnp-3025	393	29	just	just	ADV
fnp-3025	393	30	happen	happen	VERB
fnp-3025	393	31	to	to	PART
fnp-3025	393	32	be	be	AUX
fnp-3025	393	33	in	in	ADP
fnp-3025	393	34	the	the	DET
fnp-3025	393	35	vicinity	vicinity	NOUN
fnp-3025	393	36	of	of	ADP
fnp-3025	393	37	the	the	DET
fnp-3025	393	38	plaque	plaque	NOUN
fnp-3025	393	39	[	[	X
fnp-3025	393	40	139	139	NUM
fnp-3025	393	41	]	]	PUNCT
fnp-3025	393	42	.	.	PUNCT
fnp-3025	394	1	this	this	PRON
fnp-3025	394	2	is	be	AUX
fnp-3025	394	3	likely	likely	ADJ
fnp-3025	394	4	to	to	PART
fnp-3025	394	5	be	be	AUX
fnp-3025	394	6	a	a	DET
fnp-3025	394	7	general	general	ADJ
fnp-3025	394	8	rule	rule	NOUN
fnp-3025	394	9	for	for	ADP
fnp-3025	394	10	the	the	DET
fnp-3025	394	11	presence	presence	NOUN
fnp-3025	394	12	of	of	ADP
fnp-3025	394	13	specific	specific	ADJ
fnp-3025	394	14	types	type	NOUN
fnp-3025	394	15	of	of	ADP
fnp-3025	394	16	neurites	neurite	NOUN
fnp-3025	394	17	in	in	ADP
fnp-3025	394	18	plaques	plaque	NOUN
fnp-3025	394	19	,	,	PUNCT
fnp-3025	394	20	including	include	VERB
fnp-3025	394	21	those	those	PRON
fnp-3025	394	22	containing	contain	VERB
fnp-3025	394	23	markers	marker	NOUN
fnp-3025	394	24	for	for	ADP
fnp-3025	394	25	diverse	diverse	ADJ
fnp-3025	394	26	neurotransmitters	neurotransmitter	NOUN
fnp-3025	394	27	(	(	PUNCT
fnp-3025	394	28	see	see	VERB
fnp-3025	394	29	below	below	ADV
fnp-3025	394	30	)	)	PUNCT
fnp-3025	394	31	and	and	CCONJ
fnp-3025	394	32	,	,	PUNCT
fnp-3025	394	33	e.g.	e.g.	ADV
fnp-3025	394	34	,	,	PUNCT
fnp-3025	394	35	the	the	DET
fnp-3025	394	36	alpha	alpha	NOUN
fnp-3025	394	37	-	-	PUNCT
fnp-3025	394	38	synuclein	synuclein	NOUN
fnp-3025	394	39	-	-	ADJ
fnp-3025	394	40	positive	positive	ADJ
fnp-3025	394	41	neurites	neurite	NOUN
fnp-3025	394	42	in	in	ADP
fnp-3025	394	43	aβ	aβ	ADP
fnp-3025	394	44	plaques	plaque	NOUN
fnp-3025	394	45	that	that	PRON
fnp-3025	394	46	are	be	AUX
fnp-3025	394	47	sometimes	sometimes	ADV
fnp-3025	394	48	co	co	ADJ
fnp-3025	394	49	-	-	NOUN
fnp-3025	394	50	morbid	morbid	ADJ
fnp-3025	394	51	with	with	ADP
fnp-3025	394	52	synucleinopathy	synucleinopathy	NOUN
fnp-3025	394	53	in	in	ADP
fnp-3025	394	54	lewy	lewy	ADJ
fnp-3025	394	55	body	body	NOUN
fnp-3025	394	56	disease	disease	NOUN
fnp-3025	394	57	[	[	X
fnp-3025	394	58	276	276	NUM
fnp-3025	394	59	]	]	PUNCT
fnp-3025	394	60	.	.	PUNCT
fnp-3025	395	1	figure	figure	NOUN
fnp-3025	395	2	18	18	NUM
fnp-3025	395	3	.	.	PUNCT
fnp-3025	395	4	abnormal	abnormal	ADJ
fnp-3025	395	5	neurite	neurite	NOUN
fnp-3025	395	6	(	(	PUNCT
fnp-3025	395	7	top	top	ADJ
fnp-3025	395	8	)	)	PUNCT
fnp-3025	395	9	containing	contain	VERB
fnp-3025	395	10	organelles	organelle	NOUN
fnp-3025	395	11	/debris	/debris	PUNCT
fnp-3025	395	12	adjacent	adjacent	ADJ
fnp-3025	395	13	to	to	ADP
fnp-3025	395	14	fibrillar	fibrillar	ADJ
fnp-3025	395	15	amyloid	amyloid	NOUN
fnp-3025	395	16	(	(	PUNCT
fnp-3025	395	17	bottom	bottom	NOUN
fnp-3025	395	18	)	)	PUNCT
fnp-3025	395	19	in	in	ADP
fnp-3025	395	20	the	the	DET
fnp-3025	395	21	plaque	plaque	NOUN
fnp-3025	395	22	corona	corona	NOUN
fnp-3025	395	23	of	of	ADP
fnp-3025	395	24	a	a	DET
fnp-3025	395	25	patient	patient	NOUN
fnp-3025	395	26	with	with	ADP
fnp-3025	395	27	ad	ad	NOUN
fnp-3025	395	28	.	.	PUNCT
fnp-3025	396	1	bar	bar	NOUN
fnp-3025	396	2	=	=	PUNCT
fnp-3025	396	3	500	500	NUM
fnp-3025	396	4	nm	nm	NOUN
fnp-3025	396	5	.	.	PUNCT
fnp-3025	397	1	histochemically	histochemically	ADV
fnp-3025	397	2	,	,	PUNCT
fnp-3025	397	3	lysosomal	lysosomal	ADJ
fnp-3025	397	4	enzyme	enzyme	NOUN
fnp-3025	397	5	activity	activity	NOUN
fnp-3025	397	6	is	be	AUX
fnp-3025	397	7	pronounced	pronounce	VERB
fnp-3025	397	8	in	in	ADP
fnp-3025	397	9	dystrophic	dystrophic	ADJ
fnp-3025	397	10	neurites	neurite	NOUN
fnp-3025	397	11	,	,	PUNCT
fnp-3025	397	12	as	as	SCONJ
fnp-3025	397	13	is	be	AUX
fnp-3025	397	14	histochemical	histochemical	ADJ
fnp-3025	397	15	reactivity	reactivity	NOUN
fnp-3025	397	16	for	for	ADP
fnp-3025	397	17	app	app	NOUN
fnp-3025	397	18	and	and	CCONJ
fnp-3025	397	19	markers	marker	NOUN
fnp-3025	397	20	of	of	ADP
fnp-3025	397	21	degeneration	degeneration	NOUN
fnp-3025	397	22	such	such	ADJ
fnp-3025	397	23	as	as	ADP
fnp-3025	397	24	chromogranin	chromogranin	NOUN
fnp-3025	397	25	-	-	PUNCT
fnp-3025	397	26	a	a	NOUN
fnp-3025	397	27	and	and	CCONJ
fnp-3025	397	28	ubiquitin	ubiquitin	ADJ
fnp-3025	397	29	[	[	X
fnp-3025	397	30	139	139	NUM
fnp-3025	397	31	]	]	PUNCT
fnp-3025	397	32	.	.	PUNCT
fnp-3025	398	1	the	the	DET
fnp-3025	398	2	chemical	chemical	ADJ
fnp-3025	398	3	variability	variability	NOUN
fnp-3025	398	4	of	of	ADP
fnp-3025	398	5	neurites	neurite	NOUN
fnp-3025	398	6	may	may	AUX
fnp-3025	398	7	reflect	reflect	VERB
fnp-3025	398	8	,	,	PUNCT
fnp-3025	398	9	in	in	ADP
fnp-3025	398	10	addition	addition	NOUN
fnp-3025	398	11	to	to	ADP
fnp-3025	398	12	the	the	DET
fnp-3025	398	13	neurons	neuron	NOUN
fnp-3025	398	14	of	of	ADP
fnp-3025	398	15	origin	origin	NOUN
fnp-3025	398	16	,	,	PUNCT
fnp-3025	398	17	their	their	PRON
fnp-3025	398	18	stage	stage	NOUN
fnp-3025	398	19	of	of	ADP
fnp-3025	398	20	development	development	NOUN
fnp-3025	398	21	and	and	CCONJ
fnp-3025	398	22	their	their	PRON
fnp-3025	398	23	response	response	NOUN
fnp-3025	398	24	to	to	ADP
fnp-3025	398	25	injury	injury	NOUN
fnp-3025	398	26	or	or	CCONJ
fnp-3025	398	27	stress	stress	NOUN
fnp-3025	398	28	[	[	X
fnp-3025	398	29	277	277	NUM
fnp-3025	398	30	]	]	PUNCT
fnp-3025	398	31	.	.	PUNCT
fnp-3025	399	1	several	several	ADJ
fnp-3025	399	2	early	early	ADJ
fnp-3025	399	3	researchers	researcher	NOUN
fnp-3025	399	4	,	,	PUNCT
fnp-3025	399	5	including	include	VERB
fnp-3025	399	6	fischer	fischer	NOUN
fnp-3025	399	7	[	[	X
fnp-3025	399	8	117	117	NUM
fnp-3025	399	9	]	]	PUNCT
fnp-3025	399	10	and	and	CCONJ
fnp-3025	399	11	ramon	ramon	PROPN
fnp-3025	399	12	y	y	PROPN
fnp-3025	399	13	cajal	cajal	ADV
fnp-3025	399	14	(	(	PUNCT
fnp-3025	399	15	see	see	VERB
fnp-3025	399	16	[	[	X
fnp-3025	399	17	278	278	NUM
fnp-3025	399	18	]	]	PUNCT
fnp-3025	399	19	)	)	PUNCT
fnp-3025	399	20	,	,	PUNCT
fnp-3025	399	21	thought	think	VERB
fnp-3025	399	22	that	that	SCONJ
fnp-3025	399	23	the	the	DET
fnp-3025	399	24	swollen	swollen	ADJ
fnp-3025	399	25	neurites	neurite	NOUN
fnp-3025	399	26	in	in	ADP
fnp-3025	399	27	plaques	plaque	NOUN
fnp-3025	399	28	represented	represent	VERB
fnp-3025	399	29	an	an	DET
fnp-3025	399	30	attempt	attempt	NOUN
fnp-3025	399	31	by	by	ADP
fnp-3025	399	32	the	the	DET
fnp-3025	399	33	neuronal	neuronal	ADJ
fnp-3025	399	34	processes	process	NOUN
fnp-3025	399	35	to	to	ADP
fnp-3025	399	36	sprout	sprout	NOUN
fnp-3025	399	37	.	.	PUNCT
fnp-3025	400	1	since	since	SCONJ
fnp-3025	400	2	then	then	ADV
fnp-3025	400	3	,	,	PUNCT
fnp-3025	400	4	multiple	multiple	ADJ
fnp-3025	400	5	growth	growth	NOUN
fnp-3025	400	6	-	-	PUNCT
fnp-3025	400	7	promoting	promote	VERB
fnp-3025	400	8	factors	factor	NOUN
fnp-3025	400	9	have	have	AUX
fnp-3025	400	10	been	be	AUX
fnp-3025	400	11	detected	detect	VERB
fnp-3025	400	12	in	in	ADP
fnp-3025	400	13	these	these	DET
fnp-3025	400	14	neurites	neurite	NOUN
fnp-3025	400	15	[	[	X
fnp-3025	400	16	278	278	NUM
fnp-3025	400	17	,	,	PUNCT
fnp-3025	400	18	279	279	NUM
fnp-3025	400	19	]	]	PUNCT
fnp-3025	400	20	,	,	PUNCT
fnp-3025	400	21	and	and	CCONJ
fnp-3025	400	22	aβ	aβ	DET
fnp-3025	400	23	deposits	deposit	NOUN
fnp-3025	400	24	have	have	AUX
fnp-3025	400	25	been	be	AUX
fnp-3025	400	26	shown	show	VERB
fnp-3025	400	27	experimentally	experimentally	ADV
fnp-3025	400	28	to	to	PART
fnp-3025	400	29	induce	induce	VERB
fnp-3025	400	30	axonal	axonal	ADJ
fnp-3025	400	31	sprouting	sprouting	NOUN
fnp-3025	400	32	in	in	ADP
fnp-3025	400	33	the	the	DET
fnp-3025	400	34	mouse	mouse	NOUN
fnp-3025	400	35	brain	brain	NOUN
fnp-3025	401	1	[	[	X
fnp-3025	401	2	280	280	NUM
fnp-3025	401	3	]	]	PUNCT
fnp-3025	401	4	.	.	PUNCT
fnp-3025	402	1	considered	consider	VERB
fnp-3025	402	2	as	as	ADP
fnp-3025	402	3	a	a	DET
fnp-3025	402	4	whole	whole	NOUN
fnp-3025	402	5	,	,	PUNCT
fnp-3025	402	6	these	these	DET
fnp-3025	402	7	observations	observation	NOUN
fnp-3025	402	8	indicate	indicate	VERB
fnp-3025	402	9	the	the	DET
fnp-3025	402	10	presence	presence	NOUN
fnp-3025	402	11	of	of	ADP
fnp-3025	402	12	both	both	CCONJ
fnp-3025	402	13	degenerative	degenerative	ADJ
fnp-3025	402	14	and	and	CCONJ
fnp-3025	402	15	regenerative	regenerative	ADJ
fnp-3025	402	16	mechanisms	mechanism	NOUN
fnp-3025	402	17	in	in	ADP
fnp-3025	402	18	the	the	DET
fnp-3025	402	19	aberrant	aberrant	ADJ
fnp-3025	402	20	neuronal	neuronal	ADJ
fnp-3025	402	21	processes	process	NOUN
fnp-3025	402	22	that	that	PRON
fnp-3025	402	23	are	be	AUX
fnp-3025	402	24	associated	associate	VERB
fnp-3025	402	25	with	with	ADP
fnp-3025	402	26	aβ	aβ	ADP
fnp-3025	402	27	plaques	plaque	NOUN
fnp-3025	402	28	[	[	X
fnp-3025	402	29	133	133	NUM
fnp-3025	402	30	,	,	PUNCT
fnp-3025	402	31	279	279	NUM
fnp-3025	402	32	]	]	PUNCT
fnp-3025	402	33	.	.	PUNCT
fnp-3025	403	1	analyses	analysis	NOUN
fnp-3025	403	2	of	of	ADP
fnp-3025	403	3	aβ	aβ	DET
fnp-3025	403	4	plaques	plaque	NOUN
fnp-3025	403	5	in	in	ADP
fnp-3025	403	6	humans	human	NOUN
fnp-3025	403	7	and	and	CCONJ
fnp-3025	403	8	aged	age	VERB
fnp-3025	403	9	nonhuman	nonhuman	ADJ
fnp-3025	403	10	primates	primate	NOUN
fnp-3025	403	11	found	find	VERB
fnp-3025	403	12	that	that	SCONJ
fnp-3025	403	13	many	many	ADJ
fnp-3025	403	14	different	different	ADJ
fnp-3025	403	15	neurotransmitter	neurotransmitter	NOUN
fnp-3025	403	16	systems	system	NOUN
fnp-3025	403	17	contribute	contribute	VERB
fnp-3025	403	18	anomalous	anomalous	ADJ
fnp-3025	403	19	neurites	neurite	NOUN
fnp-3025	403	20	to	to	PART
fnp-3025	403	21	plaques	plaque	NOUN
fnp-3025	403	22	[	[	X
fnp-3025	403	23	281	281	NUM
fnp-3025	403	24	-	-	SYM
fnp-3025	403	25	287	287	NUM
fnp-3025	403	26	]	]	PUNCT
fnp-3025	403	27	,	,	PUNCT
fnp-3025	403	28	and	and	CCONJ
fnp-3025	403	29	that	that	SCONJ
fnp-3025	403	30	an	an	DET
fnp-3025	403	31	individual	individual	ADJ
fnp-3025	403	32	plaque	plaque	NOUN
fnp-3025	403	33	can	can	AUX
fnp-3025	403	34	contain	contain	VERB
fnp-3025	403	35	neurites	neurite	NOUN
fnp-3025	403	36	from	from	ADP
fnp-3025	403	37	multiple	multiple	ADJ
fnp-3025	403	38	sources	source	NOUN
fnp-3025	403	39	[	[	X
fnp-3025	403	40	288	288	NUM
fnp-3025	403	41	,	,	PUNCT
fnp-3025	403	42	289	289	NUM
fnp-3025	403	43	]	]	PUNCT
fnp-3025	403	44	.	.	PUNCT
fnp-3025	404	1	these	these	DET
fnp-3025	404	2	studies	study	NOUN
fnp-3025	404	3	cast	cast	VERB
fnp-3025	404	4	doubt	doubt	NOUN
fnp-3025	404	5	on	on	ADP
fnp-3025	404	6	the	the	DET
fnp-3025	404	7	hypothesis	hypothesis	NOUN
fnp-3025	404	8	[	[	X
fnp-3025	404	9	290	290	NUM
fnp-3025	404	10	]	]	PUNCT
fnp-3025	404	11	that	that	PRON
fnp-3025	404	12	plaques	plaque	NOUN
fnp-3025	404	13	emerge	emerge	VERB
fnp-3025	404	14	from	from	ADP
fnp-3025	404	15	the	the	DET
fnp-3025	404	16	regression	regression	NOUN
fnp-3025	404	17	of	of	ADP
fnp-3025	404	18	neurites	neurite	NOUN
fnp-3025	404	19	from	from	ADP
fnp-3025	404	20	a	a	DET
fnp-3025	404	21	specific	specific	ADJ
fnp-3025	404	22	transmitter	transmitter	NOUN
fnp-3025	404	23	system	system	NOUN
fnp-3025	404	24	,	,	PUNCT
fnp-3025	404	25	in	in	ADP
fnp-3025	404	26	particular	particular	ADJ
fnp-3025	404	27	the	the	DET
fnp-3025	404	28	acetylcholinergic	acetylcholinergic	NOUN
fnp-3025	404	29	neurons	neuron	NOUN
fnp-3025	404	30	of	of	ADP
fnp-3025	404	31	the	the	DET
fnp-3025	404	32	basal	basal	ADJ
fnp-3025	404	33	forebrain	forebrain	NOUN
fnp-3025	405	1	[	[	X
fnp-3025	405	2	141	141	NUM
fnp-3025	405	3	]	]	PUNCT
fnp-3025	405	4	.	.	PUNCT
fnp-3025	406	1	rather	rather	ADV
fnp-3025	406	2	,	,	PUNCT
fnp-3025	406	3	they	they	PRON
fnp-3025	406	4	highlight	highlight	VERB
fnp-3025	406	5	the	the	DET
fnp-3025	406	6	probable	probable	ADJ
fnp-3025	406	7	role	role	NOUN
fnp-3025	406	8	of	of	ADP
fnp-3025	406	9	a	a	DET
fnp-3025	406	10	common	common	ADJ
fnp-3025	406	11	catalyst	catalyst	NOUN
fnp-3025	406	12	(	(	PUNCT
fnp-3025	406	13	e.g.	e.g.	ADV
fnp-3025	406	14	,	,	PUNCT
fnp-3025	406	15	misfolded	misfolde	VERB
fnp-3025	406	16	aβ	aβ	PRON
fnp-3025	406	17	and/or	and/or	CCONJ
fnp-3025	406	18	reactive	reactive	ADJ
fnp-3025	406	19	glia	glia	PROPN
fnp-3025	406	20	)	)	PUNCT
fnp-3025	406	21	in	in	ADP
fnp-3025	406	22	driving	drive	VERB
fnp-3025	406	23	neuritic	neuritic	ADJ
fnp-3025	406	24	dystrophy	dystrophy	NOUN
fnp-3025	407	1	[	[	X
fnp-3025	407	2	139	139	NUM
fnp-3025	407	3	,	,	PUNCT
fnp-3025	407	4	289	289	NUM
fnp-3025	407	5	,	,	PUNCT
fnp-3025	407	6	291	291	NUM
fnp-3025	407	7	]	]	PUNCT
fnp-3025	407	8	.	.	PUNCT
fnp-3025	408	1	indeed	indeed	ADV
fnp-3025	408	2	,	,	PUNCT
fnp-3025	408	3	the	the	DET
fnp-3025	408	4	influential	influential	ADJ
fnp-3025	408	5	model	model	NOUN
fnp-3025	408	6	proposed	propose	VERB
fnp-3025	408	7	by	by	ADP
fnp-3025	408	8	wisniewski	wisniewski	PROPN
fnp-3025	408	9	and	and	CCONJ
fnp-3025	408	10	terry	terry	PROPN
fnp-3025	409	1	[	[	X
fnp-3025	409	2	178	178	NUM
fnp-3025	409	3	]	]	PUNCT
fnp-3025	409	4	(	(	PUNCT
fnp-3025	409	5	see	see	VERB
fnp-3025	409	6	also	also	ADV
fnp-3025	409	7	[	[	X
fnp-3025	409	8	81	81	NUM
fnp-3025	409	9	]	]	PUNCT
fnp-3025	409	10	)	)	PUNCT
fnp-3025	409	11	that	that	SCONJ
fnp-3025	409	12	posited	posit	VERB
fnp-3025	409	13	neuritic	neuritic	ADJ
fnp-3025	409	14	abnormalities	abnormality	NOUN
fnp-3025	409	15	in	in	ADP
fnp-3025	409	16	general	general	ADJ
fnp-3025	409	17	as	as	ADP
fnp-3025	409	18	the	the	DET
fnp-3025	409	19	initial	initial	ADJ
fnp-3025	409	20	stage	stage	NOUN
fnp-3025	409	21	of	of	ADP
fnp-3025	409	22	plaque	plaque	NOUN
fnp-3025	409	23	ontogeny	ontogeny	NOUN
fnp-3025	409	24	now	now	ADV
fnp-3025	409	25	seems	seem	VERB
fnp-3025	409	26	untenable	untenable	ADJ
fnp-3025	409	27	,	,	PUNCT
fnp-3025	409	28	especially	especially	ADV
fnp-3025	409	29	in	in	ADP
fnp-3025	409	30	light	light	NOUN
fnp-3025	409	31	of	of	ADP
fnp-3025	409	32	genetic	genetic	ADJ
fnp-3025	409	33	findings	finding	NOUN
fnp-3025	409	34	implicating	implicate	VERB
fnp-3025	409	35	aβ	aβ	PRON
fnp-3025	409	36	as	as	ADP
fnp-3025	409	37	the	the	DET
fnp-3025	409	38	prime	prime	ADJ
fnp-3025	409	39	mover	mover	NOUN
fnp-3025	409	40	in	in	ADP
fnp-3025	409	41	the	the	DET
fnp-3025	409	42	pathogenesis	pathogenesis	NOUN
fnp-3025	409	43	of	of	ADP
fnp-3025	409	44	ad	ad	NOUN
fnp-3025	409	45	[	[	X
fnp-3025	409	46	9	9	NUM
fnp-3025	409	47	,	,	PUNCT
fnp-3025	409	48	22	22	NUM
fnp-3025	409	49	,	,	PUNCT
fnp-3025	409	50	44	44	NUM
fnp-3025	409	51	,	,	PUNCT
fnp-3025	409	52	45	45	NUM
fnp-3025	409	53	,	,	PUNCT
fnp-3025	409	54	212	212	NUM
fnp-3025	409	55	]	]	PUNCT
fnp-3025	409	56	.	.	PUNCT
fnp-3025	410	1	even	even	ADV
fnp-3025	410	2	so	so	ADV
fnp-3025	410	3	,	,	PUNCT
fnp-3025	410	4	dysmorphic	dysmorphic	ADJ
fnp-3025	410	5	neurites	neurite	NOUN
fnp-3025	410	6	do	do	AUX
fnp-3025	410	7	influence	influence	VERB
fnp-3025	410	8	the	the	DET
fnp-3025	410	9	pathologic	pathologic	ADJ
fnp-3025	410	10	plaque	plaque	NOUN
fnp-3025	410	11	milieu	milieu	NOUN
fnp-3025	410	12	[	[	X
fnp-3025	410	13	207	207	NUM
fnp-3025	410	14	]	]	PUNCT
fnp-3025	410	15	,	,	PUNCT
fnp-3025	410	16	and	and	CCONJ
fnp-3025	410	17	it	it	PRON
fnp-3025	410	18	is	be	AUX
fnp-3025	410	19	possible	possible	ADJ
fnp-3025	410	20	that	that	SCONJ
fnp-3025	410	21	,	,	PUNCT
fnp-3025	410	22	by	by	ADP
fnp-3025	410	23	releasing	release	VERB
fnp-3025	410	24	aβ	aβ	NOUN
fnp-3025	410	25	into	into	ADP
fnp-3025	410	26	the	the	DET
fnp-3025	410	27	extracellular	extracellular	ADJ
fnp-3025	410	28	space	space	NOUN
fnp-3025	410	29	,	,	PUNCT
fnp-3025	410	30	they	they	PRON
fnp-3025	410	31	contribute	contribute	VERB
fnp-3025	410	32	to	to	ADP
fnp-3025	410	33	the	the	DET
fnp-3025	410	34	growth	growth	NOUN
fnp-3025	410	35	of	of	ADP
fnp-3025	410	36	plaques	plaque	NOUN
fnp-3025	410	37	[	[	X
fnp-3025	410	38	272	272	NUM
fnp-3025	410	39	]	]	PUNCT
fnp-3025	410	40	.	.	PUNCT
fnp-3025	411	1	in	in	ADP
fnp-3025	411	2	addition	addition	NOUN
fnp-3025	411	3	,	,	PUNCT
fnp-3025	411	4	neuritic	neuritic	ADJ
fnp-3025	411	5	aβ	aβ	NOUN
fnp-3025	411	6	plaques	plaque	NOUN
fnp-3025	411	7	are	be	AUX
fnp-3025	411	8	generally	generally	ADV
fnp-3025	411	9	more	more	ADV
fnp-3025	411	10	strongly	strongly	ADV
fnp-3025	411	11	associated	associate	VERB
fnp-3025	411	12	with	with	ADP
fnp-3025	411	13	dementia	dementia	NOUN
fnp-3025	411	14	than	than	SCONJ
fnp-3025	411	15	are	be	AUX
fnp-3025	411	16	diffuse	diffuse	ADJ
fnp-3025	411	17	plaques	plaque	NOUN
fnp-3025	411	18	[	[	X
fnp-3025	411	19	1	1	NUM
fnp-3025	411	20	,	,	PUNCT
fnp-3025	411	21	133	133	NUM
fnp-3025	411	22	,	,	PUNCT
fnp-3025	411	23	204	204	NUM
fnp-3025	411	24	]	]	PUNCT
fnp-3025	411	25	.	.	PUNCT
fnp-3025	412	1	finally	finally	ADV
fnp-3025	412	2	,	,	PUNCT
fnp-3025	412	3	the	the	DET
fnp-3025	412	4	loss	loss	NOUN
fnp-3025	412	5	of	of	ADP
fnp-3025	412	6	synapses	synapsis	NOUN
fnp-3025	412	7	correlates	correlate	VERB
fnp-3025	412	8	strongly	strongly	ADV
fnp-3025	412	9	with	with	ADP
fnp-3025	412	10	the	the	DET
fnp-3025	412	11	degree	degree	NOUN
fnp-3025	412	12	of	of	ADP
fnp-3025	412	13	dementia	dementia	NOUN
fnp-3025	412	14	in	in	ADP
fnp-3025	412	15	ad	ad	NOUN
fnp-3025	412	16	[	[	X
fnp-3025	412	17	292	292	NUM
fnp-3025	412	18	-	-	SYM
fnp-3025	412	19	295	295	NUM
fnp-3025	412	20	]	]	PUNCT
fnp-3025	412	21	;	;	PUNCT
fnp-3025	412	22	synaptic	synaptic	ADJ
fnp-3025	412	23	pathology	pathology	NOUN
fnp-3025	412	24	is	be	AUX
fnp-3025	412	25	especially	especially	ADV
fnp-3025	412	26	evident	evident	ADJ
fnp-3025	412	27	in	in	ADP
fnp-3025	412	28	the	the	DET
fnp-3025	412	29	immediate	immediate	ADJ
fnp-3025	412	30	vicinity	vicinity	NOUN
fnp-3025	412	31	of	of	ADP
fnp-3025	412	32	aβ	aβ	DET
fnp-3025	412	33	plaques	plaque	NOUN
fnp-3025	412	34	(	(	PUNCT
fnp-3025	412	35	see	see	VERB
fnp-3025	412	36	[	[	X
fnp-3025	412	37	296	296	NUM
fnp-3025	412	38	,	,	PUNCT
fnp-3025	412	39	297	297	NUM
fnp-3025	412	40	]	]	PUNCT
fnp-3025	412	41	,	,	PUNCT
fnp-3025	412	42	possibly	possibly	ADV
fnp-3025	412	43	owing	owe	VERB
fnp-3025	412	44	to	to	ADP
fnp-3025	412	45	increased	increase	VERB
fnp-3025	412	46	oligomeric	oligomeric	ADJ
fnp-3025	412	47	aβ	aβ	NOUN
fnp-3025	412	48	in	in	ADP
fnp-3025	412	49	this	this	DET
fnp-3025	412	50	region	region	NOUN
fnp-3025	413	1	[	[	X
fnp-3025	413	2	297	297	NUM
fnp-3025	413	3	]	]	PUNCT
fnp-3025	413	4	.	.	PUNCT
fnp-3025	414	1	6.2	6.2	NUM
fnp-3025	414	2	glial	glial	ADJ
fnp-3025	414	3	cells	cell	NOUN
fnp-3025	414	4	of	of	ADP
fnp-3025	414	5	the	the	DET
fnp-3025	414	6	many	many	ADJ
fnp-3025	414	7	genetic	genetic	ADJ
fnp-3025	414	8	risk	risk	NOUN
fnp-3025	414	9	factors	factor	NOUN
fnp-3025	414	10	for	for	ADP
fnp-3025	414	11	ad	ad	NOUN
fnp-3025	414	12	[	[	X
fnp-3025	414	13	298	298	NUM
fnp-3025	414	14	]	]	PUNCT
fnp-3025	414	15	,	,	PUNCT
fnp-3025	414	16	two	two	NUM
fnp-3025	414	17	of	of	ADP
fnp-3025	414	18	the	the	DET
fnp-3025	414	19	most	most	ADV
fnp-3025	414	20	potent	potent	ADJ
fnp-3025	414	21	variant	variant	ADJ
fnp-3025	414	22	genes	gene	NOUN
fnp-3025	414	23	apoe	apoe	ADJ
fnp-3025	414	24	(	(	PUNCT
fnp-3025	414	25	apolipoprotein	apolipoprotein	ADJ
fnp-3025	414	26	e	e	NOUN
fnp-3025	414	27	)	)	PUNCT
fnp-3025	414	28	and	and	CCONJ
fnp-3025	414	29	trem2	trem2	NOUN
fnp-3025	414	30	(	(	PUNCT
fnp-3025	414	31	triggering	trigger	VERB
fnp-3025	414	32	receptor	receptor	NOUN
fnp-3025	414	33	expressed	express	VERB
fnp-3025	414	34	on	on	ADP
fnp-3025	414	35	myeloid	myeloid	NOUN
fnp-3025	414	36	cells-2	cells-2	PROPN
fnp-3025	414	37	)	)	PUNCT
fnp-3025	414	38	are	be	AUX
fnp-3025	414	39	highly	highly	ADV
fnp-3025	414	40	expressed	express	VERB
fnp-3025	414	41	in	in	ADP
fnp-3025	414	42	glial	glial	ADJ
fnp-3025	414	43	cells	cell	NOUN
fnp-3025	414	44	[	[	X
fnp-3025	414	45	115	115	NUM
fnp-3025	414	46	]	]	PUNCT
fnp-3025	414	47	,	,	PUNCT
fnp-3025	414	48	as	as	SCONJ
fnp-3025	414	49	are	be	AUX
fnp-3025	414	50	several	several	ADJ
fnp-3025	414	51	other	other	ADJ
fnp-3025	414	52	ad	ad	NOUN
fnp-3025	414	53	-	-	PUNCT
fnp-3025	414	54	associated	associate	VERB
fnp-3025	414	55	genes	gene	NOUN
fnp-3025	414	56	[	[	X
fnp-3025	414	57	299	299	NUM
fnp-3025	414	58	-	-	SYM
fnp-3025	414	59	301	301	NUM
fnp-3025	414	60	]	]	PUNCT
fnp-3025	414	61	.	.	PUNCT
fnp-3025	415	1	astrocytes	astrocyte	NOUN
fnp-3025	415	2	and	and	CCONJ
fnp-3025	415	3	microglia	microglia	NOUN
fnp-3025	415	4	are	be	AUX
fnp-3025	415	5	protean	protean	ADJ
fnp-3025	415	6	and	and	CCONJ
fnp-3025	415	7	interactive	interactive	ADJ
fnp-3025	415	8	components	component	NOUN
fnp-3025	415	9	of	of	ADP
fnp-3025	415	10	the	the	DET
fnp-3025	415	11	homeostatic	homeostatic	ADJ
fnp-3025	415	12	intrinsic	intrinsic	ADJ
fnp-3025	415	13	immune	immune	ADJ
fnp-3025	415	14	system	system	NOUN
fnp-3025	415	15	in	in	ADP
fnp-3025	415	16	the	the	DET
fnp-3025	415	17	brain	brain	NOUN
fnp-3025	415	18	and	and	CCONJ
fnp-3025	415	19	spinal	spinal	ADJ
fnp-3025	415	20	cord	cord	NOUN
fnp-3025	416	1	[	[	X
fnp-3025	416	2	299	299	NUM
fnp-3025	416	3	,	,	PUNCT
fnp-3025	416	4	302	302	NUM
fnp-3025	416	5	,	,	PUNCT
fnp-3025	416	6	303	303	NUM
fnp-3025	416	7	]	]	PUNCT
fnp-3025	416	8	.	.	PUNCT
fnp-3025	417	1	histologic	histologic	ADJ
fnp-3025	417	2	,	,	PUNCT
fnp-3025	417	3	genetic	genetic	ADJ
fnp-3025	417	4	,	,	PUNCT
fnp-3025	417	5	biochemical	biochemical	ADJ
fnp-3025	417	6	and	and	CCONJ
fnp-3025	417	7	physiological	physiological	ADJ
fnp-3025	417	8	findings	finding	NOUN
fnp-3025	417	9	strongly	strongly	ADV
fnp-3025	417	10	implicate	implicate	VERB
fnp-3025	417	11	them	they	PRON
fnp-3025	417	12	in	in	ADP
fnp-3025	417	13	the	the	DET
fnp-3025	417	14	pathogenesis	pathogenesis	NOUN
fnp-3025	417	15	of	of	ADP
fnp-3025	417	16	ad	ad	NOUN
fnp-3025	417	17	[	[	X
fnp-3025	417	18	111	111	NUM
fnp-3025	417	19	-	-	SYM
fnp-3025	417	20	115	115	NUM
fnp-3025	417	21	,	,	PUNCT
fnp-3025	417	22	299	299	NUM
fnp-3025	417	23	,	,	PUNCT
fnp-3025	417	24	303	303	NUM
fnp-3025	417	25	-	-	SYM
fnp-3025	417	26	310	310	NUM
fnp-3025	417	27	]	]	PUNCT
fnp-3025	417	28	(	(	PUNCT
fnp-3025	417	29	figure	figure	NOUN
fnp-3025	417	30	19	19	NUM
fnp-3025	417	31	)	)	PUNCT
fnp-3025	417	32	.	.	PUNCT
fnp-3025	418	1	microglia	microglia	NOUN
fnp-3025	418	2	and	and	CCONJ
fnp-3025	418	3	astrocytes	astrocyte	NOUN
fnp-3025	418	4	do	do	AUX
fnp-3025	418	5	not	not	PART
fnp-3025	418	6	operate	operate	VERB
fnp-3025	418	7	independently	independently	ADV
fnp-3025	418	8	of	of	ADP
fnp-3025	418	9	one	one	NUM
fnp-3025	418	10	another	another	DET
fnp-3025	418	11	,	,	PUNCT
fnp-3025	418	12	but	but	CCONJ
fnp-3025	418	13	rather	rather	ADV
fnp-3025	418	14	jointly	jointly	ADV
fnp-3025	418	15	influence	influence	VERB
fnp-3025	418	16	aβ	aβ	NOUN
fnp-3025	418	17	processing	processing	NOUN
fnp-3025	418	18	and	and	CCONJ
fnp-3025	418	19	plaque	plaque	NOUN
fnp-3025	418	20	biology	biology	NOUN
fnp-3025	418	21	[	[	X
fnp-3025	418	22	311	311	NUM
fnp-3025	418	23	,	,	PUNCT
fnp-3025	418	24	312	312	NUM
fnp-3025	418	25	]	]	PUNCT
fnp-3025	418	26	.	.	PUNCT
fnp-3025	419	1	in	in	ADP
fnp-3025	419	2	the	the	DET
fnp-3025	419	3	vicinity	vicinity	NOUN
fnp-3025	419	4	of	of	ADP
fnp-3025	419	5	aβ	aβ	NOUN
fnp-3025	419	6	-	-	PUNCT
fnp-3025	419	7	amyloid	amyloid	NOUN
fnp-3025	419	8	,	,	PUNCT
fnp-3025	419	9	these	these	DET
fnp-3025	419	10	glial	glial	ADJ
fnp-3025	419	11	cells	cell	NOUN
fnp-3025	419	12	together	together	ADV
fnp-3025	419	13	form	form	VERB
fnp-3025	419	14	a	a	DET
fnp-3025	419	15	partially	partially	ADV
fnp-3025	419	16	integrated	integrated	ADJ
fnp-3025	419	17	‘	'	PUNCT
fnp-3025	419	18	reactive	reactive	ADJ
fnp-3025	419	19	glial	glial	ADJ
fnp-3025	419	20	net	net	NOUN
fnp-3025	419	21	’	'	PUNCT
fnp-3025	419	22	[	[	X
fnp-3025	419	23	313	313	NUM
fnp-3025	419	24	]	]	PUNCT
fnp-3025	419	25	that	that	PRON
fnp-3025	419	26	,	,	PUNCT
fnp-3025	419	27	while	while	SCONJ
fnp-3025	419	28	considered	consider	VERB
fnp-3025	419	29	to	to	PART
fnp-3025	419	30	be	be	AUX
fnp-3025	419	31	an	an	DET
fnp-3025	419	32	attempt	attempt	NOUN
fnp-3025	419	33	to	to	PART
fnp-3025	419	34	shield	shield	VERB
fnp-3025	419	35	nearby	nearby	ADJ
fnp-3025	419	36	neurons	neuron	NOUN
fnp-3025	419	37	from	from	ADP
fnp-3025	419	38	aβ	aβ	DET
fnp-3025	419	39	aggregates	aggregate	NOUN
fnp-3025	419	40	[	[	X
fnp-3025	419	41	314	314	NUM
fnp-3025	419	42	]	]	PUNCT
fnp-3025	419	43	,	,	PUNCT
fnp-3025	419	44	ultimately	ultimately	ADV
fnp-3025	419	45	engenders	engender	VERB
fnp-3025	419	46	a	a	DET
fnp-3025	419	47	neurotoxic	neurotoxic	ADJ
fnp-3025	419	48	inflammatory	inflammatory	ADJ
fnp-3025	419	49	microenvironment	microenvironment	NOUN
fnp-3025	419	50	[	[	X
fnp-3025	419	51	313	313	NUM
fnp-3025	419	52	]	]	PUNCT
fnp-3025	419	53	.	.	PUNCT
fnp-3025	420	1	figure	figure	NOUN
fnp-3025	420	2	19	19	NUM
fnp-3025	420	3	.	.	PUNCT
fnp-3025	421	1	reactive	reactive	ADJ
fnp-3025	421	2	astrocytes	astrocyte	NOUN
fnp-3025	421	3	(	(	PUNCT
fnp-3025	421	4	left	leave	VERB
fnp-3025	421	5	;	;	PUNCT
fnp-3025	421	6	antibody	antibody	NOUN
fnp-3025	421	7	to	to	ADP
fnp-3025	421	8	gfap	gfap	ADJ
fnp-3025	421	9	)	)	PUNCT
fnp-3025	421	10	and	and	CCONJ
fnp-3025	421	11	microglia	microglia	ADJ
fnp-3025	421	12	(	(	PUNCT
fnp-3025	421	13	right	right	ADJ
fnp-3025	421	14	;	;	PUNCT
fnp-3025	421	15	antibody	antibody	NOUN
fnp-3025	421	16	to	to	ADP
fnp-3025	421	17	iba1	iba1	PROPN
fnp-3025	421	18	)	)	PUNCT
fnp-3025	421	19	in	in	ADP
fnp-3025	421	20	cortical	cortical	ADJ
fnp-3025	421	21	aβ	aβ	NOUN
fnp-3025	421	22	plaques	plaque	NOUN
fnp-3025	421	23	of	of	ADP
fnp-3025	421	24	two	two	NUM
fnp-3025	421	25	ad	ad	NOUN
fnp-3025	421	26	patients	patient	NOUN
fnp-3025	421	27	.	.	PUNCT
fnp-3025	422	1	despite	despite	SCONJ
fnp-3025	422	2	some	some	DET
fnp-3025	422	3	overlap	overlap	NOUN
fnp-3025	422	4	of	of	ADP
fnp-3025	422	5	the	the	DET
fnp-3025	422	6	two	two	NUM
fnp-3025	422	7	cell	cell	NOUN
fnp-3025	422	8	types	type	NOUN
fnp-3025	422	9	within	within	ADP
fnp-3025	422	10	plaques	plaque	NOUN
fnp-3025	422	11	,	,	PUNCT
fnp-3025	422	12	astrocytic	astrocytic	ADJ
fnp-3025	422	13	somata	somata	NOUN
fnp-3025	422	14	tend	tend	VERB
fnp-3025	422	15	to	to	PART
fnp-3025	422	16	be	be	AUX
fnp-3025	422	17	more	more	ADV
fnp-3025	422	18	peripherally	peripherally	ADV
fnp-3025	422	19	located	locate	VERB
fnp-3025	422	20	than	than	SCONJ
fnp-3025	422	21	are	be	AUX
fnp-3025	422	22	microglial	microglial	ADJ
fnp-3025	422	23	somata	somata	NOUN
fnp-3025	422	24	.	.	PUNCT
fnp-3025	423	1	bar	bar	NOUN
fnp-3025	423	2	=	=	SYM
fnp-3025	423	3	20μm	20μm	NOUN
fnp-3025	423	4	for	for	ADP
fnp-3025	423	5	both	both	DET
fnp-3025	423	6	panels	panel	NOUN
fnp-3025	423	7	.	.	PUNCT
fnp-3025	424	1	inflammation	inflammation	NOUN
fnp-3025	424	2	is	be	AUX
fnp-3025	424	3	both	both	CCONJ
fnp-3025	424	4	a	a	DET
fnp-3025	424	5	risk	risk	NOUN
fnp-3025	424	6	factor	factor	NOUN
fnp-3025	424	7	for	for	ADP
fnp-3025	424	8	,	,	PUNCT
fnp-3025	424	9	and	and	CCONJ
fnp-3025	424	10	a	a	DET
fnp-3025	424	11	result	result	NOUN
fnp-3025	424	12	of	of	ADP
fnp-3025	424	13	,	,	PUNCT
fnp-3025	424	14	the	the	DET
fnp-3025	424	15	deposition	deposition	NOUN
fnp-3025	424	16	of	of	ADP
fnp-3025	424	17	aβ	aβ	PRON
fnp-3025	424	18	in	in	ADP
fnp-3025	424	19	the	the	DET
fnp-3025	424	20	brain	brain	NOUN
fnp-3025	425	1	[	[	X
fnp-3025	425	2	45	45	NUM
fnp-3025	425	3	,	,	PUNCT
fnp-3025	425	4	315	315	NUM
fnp-3025	425	5	]	]	PUNCT
fnp-3025	425	6	.	.	PUNCT
fnp-3025	426	1	the	the	DET
fnp-3025	426	2	recruitment	recruitment	NOUN
fnp-3025	426	3	and	and	CCONJ
fnp-3025	426	4	activation	activation	NOUN
fnp-3025	426	5	of	of	ADP
fnp-3025	426	6	glial	glial	ADJ
fnp-3025	426	7	cells	cell	NOUN
fnp-3025	426	8	by	by	ADP
fnp-3025	426	9	aβ	aβ	DET
fnp-3025	426	10	plaques	plaque	NOUN
fnp-3025	426	11	has	have	AUX
fnp-3025	426	12	been	be	AUX
fnp-3025	426	13	likened	liken	VERB
fnp-3025	426	14	to	to	ADP
fnp-3025	426	15	a	a	DET
fnp-3025	426	16	local	local	ADJ
fnp-3025	426	17	inflammatory	inflammatory	ADJ
fnp-3025	426	18	reaction	reaction	NOUN
fnp-3025	426	19	to	to	ADP
fnp-3025	426	20	a	a	DET
fnp-3025	426	21	foreign	foreign	ADJ
fnp-3025	426	22	body	body	NOUN
fnp-3025	426	23	[	[	X
fnp-3025	426	24	138	138	NUM
fnp-3025	426	25	,	,	PUNCT
fnp-3025	426	26	139	139	NUM
fnp-3025	426	27	]	]	PUNCT
fnp-3025	426	28	,	,	PUNCT
fnp-3025	426	29	although	although	SCONJ
fnp-3025	426	30	glia	glia	NOUN
fnp-3025	426	31	contribute	contribute	VERB
fnp-3025	426	32	to	to	ADP
fnp-3025	426	33	the	the	DET
fnp-3025	426	34	pathobiology	pathobiology	NOUN
fnp-3025	426	35	of	of	ADP
fnp-3025	426	36	plaques	plaque	NOUN
fnp-3025	426	37	in	in	ADP
fnp-3025	426	38	complex	complex	ADJ
fnp-3025	426	39	ways	way	NOUN
fnp-3025	426	40	[	[	X
fnp-3025	426	41	299	299	NUM
fnp-3025	426	42	,	,	PUNCT
fnp-3025	426	43	302	302	NUM
fnp-3025	426	44	,	,	PUNCT
fnp-3025	426	45	305	305	NUM
fnp-3025	426	46	,	,	PUNCT
fnp-3025	426	47	309	309	NUM
fnp-3025	426	48	,	,	PUNCT
fnp-3025	426	49	312	312	NUM
fnp-3025	426	50	,	,	PUNCT
fnp-3025	426	51	316	316	NUM
fnp-3025	426	52	-	-	SYM
fnp-3025	426	53	318	318	NUM
fnp-3025	426	54	]	]	PUNCT
fnp-3025	426	55	.	.	PUNCT
fnp-3025	427	1	mouse	mouse	NOUN
fnp-3025	427	2	models	model	NOUN
fnp-3025	427	3	have	have	AUX
fnp-3025	427	4	enabled	enable	VERB
fnp-3025	427	5	a	a	DET
fnp-3025	427	6	dynamic	dynamic	ADJ
fnp-3025	427	7	view	view	NOUN
fnp-3025	427	8	of	of	ADP
fnp-3025	427	9	glial	glial	ADJ
fnp-3025	427	10	function	function	NOUN
fnp-3025	427	11	and	and	CCONJ
fnp-3025	427	12	the	the	DET
fnp-3025	427	13	general	general	ADJ
fnp-3025	427	14	biology	biology	NOUN
fnp-3025	427	15	of	of	ADP
fnp-3025	427	16	plaques	plaque	NOUN
fnp-3025	427	17	,	,	PUNCT
fnp-3025	427	18	whereas	whereas	SCONJ
fnp-3025	427	19	the	the	DET
fnp-3025	427	20	genetic	genetic	ADJ
fnp-3025	427	21	and	and	CCONJ
fnp-3025	427	22	physiologic	physiologic	ADJ
fnp-3025	427	23	analysis	analysis	NOUN
fnp-3025	427	24	of	of	ADP
fnp-3025	427	25	glia	glia	NOUN
fnp-3025	427	26	in	in	ADP
fnp-3025	427	27	human	human	ADJ
fnp-3025	427	28	ad	ad	NOUN
fnp-3025	427	29	is	be	AUX
fnp-3025	427	30	much	much	ADV
fnp-3025	427	31	less	less	ADV
fnp-3025	427	32	advanced	advanced	ADJ
fnp-3025	427	33	[	[	X
fnp-3025	427	34	299	299	NUM
fnp-3025	427	35	]	]	PUNCT
fnp-3025	427	36	.	.	PUNCT
fnp-3025	428	1	even	even	ADV
fnp-3025	428	2	given	give	VERB
fnp-3025	428	3	the	the	DET
fnp-3025	428	4	caveat	caveat	NOUN
fnp-3025	428	5	that	that	SCONJ
fnp-3025	428	6	glia	glia	NOUN
fnp-3025	428	7	differ	differ	VERB
fnp-3025	428	8	in	in	ADP
fnp-3025	428	9	humans	human	NOUN
fnp-3025	428	10	compared	compare	VERB
fnp-3025	428	11	to	to	ADP
fnp-3025	428	12	other	other	ADJ
fnp-3025	428	13	species	specie	NOUN
fnp-3025	428	14	[	[	X
fnp-3025	428	15	316	316	NUM
fnp-3025	428	16	,	,	PUNCT
fnp-3025	428	17	319	319	NUM
fnp-3025	428	18	,	,	PUNCT
fnp-3025	428	19	320	320	NUM
fnp-3025	428	20	]	]	PUNCT
fnp-3025	428	21	,	,	PUNCT
fnp-3025	428	22	mice	mouse	NOUN
fnp-3025	428	23	have	have	AUX
fnp-3025	428	24	furnished	furnish	VERB
fnp-3025	428	25	unique	unique	ADJ
fnp-3025	428	26	insights	insight	NOUN
fnp-3025	428	27	into	into	ADP
fnp-3025	428	28	glial	glial	ADJ
fnp-3025	428	29	functionality	functionality	NOUN
fnp-3025	428	30	in	in	ADP
fnp-3025	428	31	the	the	DET
fnp-3025	428	32	living	live	VERB
fnp-3025	428	33	brain	brain	NOUN
fnp-3025	429	1	[	[	X
fnp-3025	429	2	304	304	NUM
fnp-3025	429	3	,	,	PUNCT
fnp-3025	429	4	316	316	NUM
fnp-3025	429	5	,	,	PUNCT
fnp-3025	429	6	321	321	NUM
fnp-3025	429	7	-	-	SYM
fnp-3025	429	8	324	324	NUM
fnp-3025	429	9	]	]	PUNCT
fnp-3025	429	10	.	.	PUNCT
fnp-3025	430	1	a	a	DET
fnp-3025	430	2	growing	grow	VERB
fnp-3025	430	3	literature	literature	NOUN
fnp-3025	430	4	underscores	underscore	VERB
fnp-3025	430	5	the	the	DET
fnp-3025	430	6	ability	ability	NOUN
fnp-3025	430	7	of	of	ADP
fnp-3025	430	8	both	both	DET
fnp-3025	430	9	microglia	microglia	NOUN
fnp-3025	430	10	and	and	CCONJ
fnp-3025	430	11	astrocytes	astrocyte	NOUN
fnp-3025	430	12	to	to	PART
fnp-3025	430	13	adopt	adopt	VERB
fnp-3025	430	14	different	different	ADJ
fnp-3025	430	15	physiologic	physiologic	ADJ
fnp-3025	430	16	states	state	NOUN
fnp-3025	430	17	that	that	PRON
fnp-3025	430	18	influence	influence	VERB
fnp-3025	430	19	how	how	SCONJ
fnp-3025	430	20	they	they	PRON
fnp-3025	430	21	contribute	contribute	VERB
fnp-3025	430	22	positively	positively	ADV
fnp-3025	430	23	or	or	CCONJ
fnp-3025	430	24	negatively	negatively	ADV
fnp-3025	430	25	to	to	ADP
fnp-3025	430	26	ad	ad	NOUN
fnp-3025	430	27	(	(	PUNCT
fnp-3025	430	28	see	see	VERB
fnp-3025	430	29	,	,	PUNCT
fnp-3025	430	30	e.g.	e.g.	ADV
fnp-3025	430	31	,	,	PUNCT
fnp-3025	430	32	[	[	X
fnp-3025	430	33	299	299	NUM
fnp-3025	430	34	,	,	PUNCT
fnp-3025	430	35	303	303	NUM
fnp-3025	430	36	,	,	PUNCT
fnp-3025	430	37	306	306	NUM
fnp-3025	430	38	]	]	PUNCT
fnp-3025	430	39	)	)	PUNCT
fnp-3025	430	40	.	.	PUNCT
fnp-3025	431	1	current	current	ADJ
fnp-3025	431	2	views	view	NOUN
fnp-3025	431	3	of	of	ADP
fnp-3025	431	4	glial	glial	ADJ
fnp-3025	431	5	cells	cell	NOUN
fnp-3025	431	6	thus	thus	ADV
fnp-3025	431	7	emphasize	emphasize	VERB
fnp-3025	431	8	their	their	PRON
fnp-3025	431	9	dual	dual	ADJ
fnp-3025	431	10	role	role	NOUN
fnp-3025	431	11	in	in	ADP
fnp-3025	431	12	the	the	DET
fnp-3025	431	13	pathobiology	pathobiology	NOUN
fnp-3025	431	14	of	of	ADP
fnp-3025	431	15	ad	ad	NOUN
fnp-3025	431	16	:	:	PUNCT
fnp-3025	431	17	they	they	PRON
fnp-3025	431	18	participate	participate	VERB
fnp-3025	431	19	in	in	ADP
fnp-3025	431	20	the	the	DET
fnp-3025	431	21	clearance	clearance	NOUN
fnp-3025	431	22	of	of	ADP
fnp-3025	431	23	aberrant	aberrant	ADJ
fnp-3025	431	24	aβ	aβ	ADP
fnp-3025	431	25	and	and	CCONJ
fnp-3025	431	26	other	other	ADJ
fnp-3025	431	27	debris	debris	NOUN
fnp-3025	431	28	,	,	PUNCT
fnp-3025	431	29	but	but	CCONJ
fnp-3025	431	30	they	they	PRON
fnp-3025	431	31	also	also	ADV
fnp-3025	431	32	can	can	AUX
fnp-3025	431	33	secrete	secrete	VERB
fnp-3025	431	34	a	a	DET
fnp-3025	431	35	variety	variety	NOUN
fnp-3025	431	36	of	of	ADP
fnp-3025	431	37	inflammationand	inflammationand	PROPN
fnp-3025	431	38	cell	cell	NOUN
fnp-3025	431	39	-	-	PUNCT
fnp-3025	431	40	stress	stress	NOUN
fnp-3025	431	41	-	-	PUNCT
fnp-3025	431	42	related	relate	VERB
fnp-3025	431	43	molecules	molecule	NOUN
fnp-3025	431	44	[	[	X
fnp-3025	431	45	304	304	NUM
fnp-3025	431	46	,	,	PUNCT
fnp-3025	431	47	325	325	NUM
fnp-3025	431	48	,	,	PUNCT
fnp-3025	431	49	326	326	NUM
fnp-3025	431	50	]	]	PUNCT
fnp-3025	431	51	.	.	PUNCT
fnp-3025	432	1	much	much	ADJ
fnp-3025	432	2	contemporary	contemporary	ADJ
fnp-3025	432	3	research	research	NOUN
fnp-3025	432	4	seeks	seek	VERB
fnp-3025	432	5	to	to	PART
fnp-3025	432	6	define	define	VERB
fnp-3025	432	7	and	and	CCONJ
fnp-3025	432	8	disentangle	disentangle	VERB
fnp-3025	432	9	these	these	DET
fnp-3025	432	10	intricate	intricate	ADJ
fnp-3025	432	11	and	and	CCONJ
fnp-3025	432	12	seemingly	seemingly	ADV
fnp-3025	432	13	incompatible	incompatible	ADJ
fnp-3025	432	14	mechanisms	mechanism	NOUN
fnp-3025	432	15	.	.	PUNCT
fnp-3025	433	1	6.2.1	6.2.1	NUM
fnp-3025	433	2	microglia	microglia	NOUN
fnp-3025	433	3	activated	activate	VERB
fnp-3025	433	4	microglia	microglia	NOUN
fnp-3025	433	5	are	be	AUX
fnp-3025	433	6	intimately	intimately	ADV
fnp-3025	433	7	associated	associate	VERB
fnp-3025	433	8	with	with	ADP
fnp-3025	433	9	the	the	DET
fnp-3025	433	10	fibrillar	fibrillar	ADJ
fnp-3025	433	11	aβ	aβ	NOUN
fnp-3025	433	12	in	in	ADP
fnp-3025	433	13	classical	classical	ADJ
fnp-3025	433	14	aβ	aβ	DET
fnp-3025	433	15	plaques	plaque	NOUN
fnp-3025	433	16	[	[	X
fnp-3025	433	17	139	139	NUM
fnp-3025	433	18	,	,	PUNCT
fnp-3025	433	19	327	327	NUM
fnp-3025	433	20	-	-	SYM
fnp-3025	433	21	330	330	NUM
fnp-3025	433	22	]	]	PUNCT
fnp-3025	433	23	(	(	PUNCT
fnp-3025	433	24	figure	figure	NOUN
fnp-3025	433	25	20	20	NUM
fnp-3025	433	26	)	)	PUNCT
fnp-3025	433	27	.	.	PUNCT
fnp-3025	434	1	they	they	PRON
fnp-3025	434	2	occupy	occupy	VERB
fnp-3025	434	3	much	much	ADJ
fnp-3025	434	4	of	of	ADP
fnp-3025	434	5	the	the	DET
fnp-3025	434	6	space	space	NOUN
fnp-3025	434	7	between	between	ADP
fnp-3025	434	8	the	the	DET
fnp-3025	434	9	plaque	plaque	NOUN
fnp-3025	434	10	core	core	NOUN
fnp-3025	434	11	and	and	CCONJ
fnp-3025	434	12	outer	outer	ADJ
fnp-3025	434	13	corona	corona	NOUN
fnp-3025	434	14	,	,	PUNCT
fnp-3025	434	15	and	and	CCONJ
fnp-3025	434	16	their	their	PRON
fnp-3025	434	17	processes	process	NOUN
fnp-3025	434	18	interdigitate	interdigitate	VERB
fnp-3025	434	19	with	with	ADP
fnp-3025	434	20	the	the	DET
fnp-3025	434	21	bundles	bundle	NOUN
fnp-3025	434	22	of	of	ADP
fnp-3025	434	23	amyloid	amyloid	NOUN
fnp-3025	434	24	[	[	X
fnp-3025	434	25	311	311	NUM
fnp-3025	434	26	,	,	PUNCT
fnp-3025	434	27	327	327	NUM
fnp-3025	434	28	]	]	PUNCT
fnp-3025	434	29	.	.	PUNCT
fnp-3025	435	1	the	the	DET
fnp-3025	435	2	discovery	discovery	NOUN
fnp-3025	435	3	that	that	PRON
fnp-3025	435	4	loss	loss	NOUN
fnp-3025	435	5	of	of	ADP
fnp-3025	435	6	function	function	NOUN
fnp-3025	435	7	mutations	mutation	NOUN
fnp-3025	435	8	in	in	ADP
fnp-3025	435	9	trem2	trem2	NOUN
fnp-3025	435	10	are	be	AUX
fnp-3025	435	11	a	a	DET
fnp-3025	435	12	strong	strong	ADJ
fnp-3025	435	13	risk	risk	NOUN
fnp-3025	435	14	factor	factor	NOUN
fnp-3025	435	15	for	for	ADP
fnp-3025	435	16	ad	ad	NOUN
fnp-3025	435	17	has	have	AUX
fnp-3025	435	18	heightened	heighten	VERB
fnp-3025	435	19	interest	interest	NOUN
fnp-3025	435	20	in	in	ADP
fnp-3025	435	21	the	the	DET
fnp-3025	435	22	role	role	NOUN
fnp-3025	435	23	of	of	ADP
fnp-3025	435	24	microglia	microglia	NOUN
fnp-3025	435	25	in	in	ADP
fnp-3025	435	26	neurodegeneration	neurodegeneration	NOUN
fnp-3025	435	27	[	[	X
fnp-3025	435	28	299	299	NUM
fnp-3025	435	29	,	,	PUNCT
fnp-3025	435	30	306	306	NUM
fnp-3025	435	31	]	]	PUNCT
fnp-3025	435	32	.	.	PUNCT
fnp-3025	436	1	trem2	trem2	NOUN
fnp-3025	436	2	is	be	AUX
fnp-3025	436	3	a	a	DET
fnp-3025	436	4	cell	cell	NOUN
fnp-3025	436	5	-	-	PUNCT
fnp-3025	436	6	surface	surface	NOUN
fnp-3025	436	7	immune	immune	ADJ
fnp-3025	436	8	receptor	receptor	NOUN
fnp-3025	436	9	on	on	ADP
fnp-3025	436	10	many	many	ADJ
fnp-3025	436	11	myeloid	myeloid	ADJ
fnp-3025	436	12	cells	cell	NOUN
fnp-3025	436	13	,	,	PUNCT
fnp-3025	436	14	including	include	VERB
fnp-3025	436	15	microglia	microglia	NOUN
fnp-3025	436	16	,	,	PUNCT
fnp-3025	436	17	which	which	PRON
fnp-3025	436	18	exclusively	exclusively	ADV
fnp-3025	436	19	express	express	VERB
fnp-3025	436	20	trem2	trem2	NOUN
fnp-3025	436	21	in	in	ADP
fnp-3025	436	22	the	the	DET
fnp-3025	436	23	brain	brain	NOUN
fnp-3025	437	1	[	[	X
fnp-3025	437	2	306	306	NUM
fnp-3025	437	3	]	]	PUNCT
fnp-3025	437	4	.	.	PUNCT
fnp-3025	438	1	the	the	DET
fnp-3025	438	2	production	production	NOUN
fnp-3025	438	3	of	of	ADP
fnp-3025	438	4	trem2	trem2	NOUN
fnp-3025	438	5	is	be	AUX
fnp-3025	438	6	increased	increase	VERB
fnp-3025	438	7	in	in	ADP
fnp-3025	438	8	ad	ad	NOUN
fnp-3025	438	9	[	[	X
fnp-3025	438	10	331	331	NUM
fnp-3025	438	11	]	]	PUNCT
fnp-3025	438	12	,	,	PUNCT
fnp-3025	438	13	and	and	CCONJ
fnp-3025	438	14	it	it	PRON
fnp-3025	438	15	mediates	mediate	VERB
fnp-3025	438	16	the	the	DET
fnp-3025	438	17	activation	activation	NOUN
fnp-3025	438	18	and	and	CCONJ
fnp-3025	438	19	responsiveness	responsiveness	NOUN
fnp-3025	438	20	of	of	ADP
fnp-3025	438	21	microglia	microglia	NOUN
fnp-3025	438	22	to	to	ADP
fnp-3025	438	23	aβ	aβ	NOUN
fnp-3025	438	24	-	-	PUNCT
fnp-3025	438	25	amyloid	amyloid	NOUN
fnp-3025	438	26	plaques	plaque	NOUN
fnp-3025	439	1	[	[	X
fnp-3025	439	2	332	332	NUM
fnp-3025	439	3	]	]	PUNCT
fnp-3025	439	4	.	.	PUNCT
fnp-3025	440	1	microglia	microglia	NOUN
fnp-3025	440	2	have	have	AUX
fnp-3025	440	3	been	be	AUX
fnp-3025	440	4	thought	think	VERB
fnp-3025	440	5	to	to	ADP
fnp-3025	440	6	either	either	CCONJ
fnp-3025	440	7	phagocytose	phagocytose	VERB
fnp-3025	440	8	[	[	X
fnp-3025	440	9	139	139	NUM
fnp-3025	440	10	]	]	PUNCT
fnp-3025	440	11	or	or	CCONJ
fnp-3025	440	12	produce	produce	VERB
fnp-3025	440	13	[	[	X
fnp-3025	440	14	311	311	NUM
fnp-3025	440	15	]	]	X
fnp-3025	440	16	multimeric	multimeric	PROPN
fnp-3025	440	17	aβ	aβ	PROPN
fnp-3025	440	18	,	,	PUNCT
fnp-3025	440	19	and	and	CCONJ
fnp-3025	440	20	their	their	PRON
fnp-3025	440	21	functional	functional	ADJ
fnp-3025	440	22	variability	variability	NOUN
fnp-3025	440	23	makes	make	VERB
fnp-3025	440	24	both	both	DET
fnp-3025	440	25	actions	action	NOUN
fnp-3025	440	26	conceivable	conceivable	ADJ
fnp-3025	440	27	,	,	PUNCT
fnp-3025	440	28	depending	depend	VERB
fnp-3025	440	29	on	on	ADP
fnp-3025	440	30	the	the	DET
fnp-3025	440	31	circumstances	circumstance	NOUN
fnp-3025	440	32	.	.	PUNCT
fnp-3025	441	1	on	on	ADP
fnp-3025	441	2	the	the	DET
fnp-3025	441	3	one	one	NUM
fnp-3025	441	4	hand	hand	NOUN
fnp-3025	441	5	,	,	PUNCT
fnp-3025	441	6	there	there	PRON
fnp-3025	441	7	is	be	VERB
fnp-3025	441	8	evidence	evidence	NOUN
fnp-3025	441	9	that	that	SCONJ
fnp-3025	441	10	microglia	microglia	NOUN
fnp-3025	441	11	normally	normally	ADV
fnp-3025	441	12	impede	impede	VERB
fnp-3025	441	13	the	the	DET
fnp-3025	441	14	generation	generation	NOUN
fnp-3025	441	15	of	of	ADP
fnp-3025	441	16	aβ	aβ	NOUN
fnp-3025	441	17	plaques	plaque	NOUN
fnp-3025	441	18	;	;	PUNCT
fnp-3025	441	19	inhibition	inhibition	NOUN
fnp-3025	441	20	of	of	ADP
fnp-3025	441	21	microglial	microglial	ADJ
fnp-3025	441	22	functionality	functionality	NOUN
fnp-3025	441	23	in	in	ADP
fnp-3025	441	24	mice	mouse	NOUN
fnp-3025	441	25	was	be	AUX
fnp-3025	441	26	found	find	VERB
fnp-3025	441	27	to	to	PART
fnp-3025	441	28	increase	increase	VERB
fnp-3025	441	29	plaque	plaque	NOUN
fnp-3025	441	30	load	load	NOUN
fnp-3025	441	31	[	[	X
fnp-3025	441	32	333	333	NUM
fnp-3025	441	33	,	,	PUNCT
fnp-3025	441	34	334	334	NUM
fnp-3025	441	35	]	]	PUNCT
fnp-3025	441	36	,	,	PUNCT
fnp-3025	441	37	and	and	CCONJ
fnp-3025	441	38	microglia	microglia	NOUN
fnp-3025	441	39	contribute	contribute	VERB
fnp-3025	441	40	to	to	ADP
fnp-3025	441	41	the	the	DET
fnp-3025	441	42	clearance	clearance	NOUN
fnp-3025	441	43	of	of	ADP
fnp-3025	441	44	dense	dense	ADJ
fnp-3025	441	45	-	-	PUNCT
fnp-3025	441	46	core	core	NOUN
fnp-3025	441	47	plaques	plaque	NOUN
fnp-3025	441	48	following	follow	VERB
fnp-3025	441	49	anti	anti	ADJ
fnp-3025	441	50	-	-	ADJ
fnp-3025	441	51	aβ	aβ	ADJ
fnp-3025	441	52	immunization	immunization	NOUN
fnp-3025	441	53	therapy	therapy	NOUN
fnp-3025	441	54	[	[	X
fnp-3025	441	55	335	335	NUM
fnp-3025	441	56	]	]	PUNCT
fnp-3025	441	57	(	(	PUNCT
fnp-3025	441	58	see	see	VERB
fnp-3025	441	59	also	also	ADV
fnp-3025	441	60	the	the	DET
fnp-3025	441	61	analysis	analysis	NOUN
fnp-3025	441	62	of	of	ADP
fnp-3025	441	63	immunized	immunize	VERB
fnp-3025	441	64	humans	human	NOUN
fnp-3025	441	65	by	by	ADP
fnp-3025	441	66	nicoll	nicoll	PROPN
fnp-3025	441	67	and	and	CCONJ
fnp-3025	441	68	colleagues	colleague	NOUN
fnp-3025	441	69	[	[	X
fnp-3025	441	70	336	336	NUM
fnp-3025	441	71	]	]	PUNCT
fnp-3025	441	72	)	)	PUNCT
fnp-3025	441	73	.	.	PUNCT
fnp-3025	442	1	additionally	additionally	ADV
fnp-3025	442	2	,	,	PUNCT
fnp-3025	442	3	studies	study	NOUN
fnp-3025	442	4	in	in	ADP
fnp-3025	442	5	mice	mouse	NOUN
fnp-3025	442	6	indicate	indicate	VERB
fnp-3025	442	7	that	that	SCONJ
fnp-3025	442	8	trem2	trem2	NOUN
fnp-3025	442	9	signaling	signal	VERB
fnp-3025	442	10	transforms	transform	VERB
fnp-3025	442	11	homeostatic	homeostatic	ADJ
fnp-3025	442	12	microglia	microglia	NOUN
fnp-3025	442	13	into	into	ADP
fnp-3025	442	14	disease	disease	NOUN
fnp-3025	442	15	-	-	PUNCT
fnp-3025	442	16	associated	associate	VERB
fnp-3025	442	17	microglia	microglia	NOUN
fnp-3025	442	18	(	(	PUNCT
fnp-3025	442	19	dam	dam	NOUN
fnp-3025	442	20	)	)	PUNCT
fnp-3025	442	21	,	,	PUNCT
fnp-3025	442	22	in	in	ADP
fnp-3025	442	23	which	which	DET
fnp-3025	442	24	state	state	NOUN
fnp-3025	442	25	they	they	PRON
fnp-3025	442	26	phagocytose	phagocytose	VERB
fnp-3025	442	27	aβ	aβ	PRON
fnp-3025	442	28	in	in	ADP
fnp-3025	442	29	plaques	plaque	NOUN
fnp-3025	443	1	[	[	X
fnp-3025	443	2	306	306	NUM
fnp-3025	443	3	,	,	PUNCT
fnp-3025	443	4	337	337	NUM
fnp-3025	443	5	]	]	PUNCT
fnp-3025	443	6	.	.	PUNCT
fnp-3025	444	1	impeding	impede	VERB
fnp-3025	444	2	trem2	trem2	NOUN
fnp-3025	444	3	functionality	functionality	NOUN
fnp-3025	444	4	in	in	ADP
fnp-3025	444	5	microglia	microglia	ADJ
fnp-3025	444	6	reduces	reduce	VERB
fnp-3025	444	7	the	the	DET
fnp-3025	444	8	binding	binding	NOUN
fnp-3025	444	9	of	of	ADP
fnp-3025	444	10	apoe	apoe	NOUN
fnp-3025	444	11	to	to	ADP
fnp-3025	444	12	aβ	aβ	NOUN
fnp-3025	444	13	-	-	PUNCT
fnp-3025	444	14	amyloid	amyloid	NOUN
fnp-3025	444	15	in	in	ADP
fnp-3025	444	16	plaques	plaque	NOUN
fnp-3025	444	17	and	and	CCONJ
fnp-3025	444	18	augments	augment	VERB
fnp-3025	444	19	the	the	DET
fnp-3025	444	20	seeded	seeded	ADJ
fnp-3025	444	21	propagation	propagation	NOUN
fnp-3025	444	22	of	of	ADP
fnp-3025	444	23	aβ	aβ	NOUN
fnp-3025	444	24	-	-	PUNCT
fnp-3025	444	25	amyloid	amyloid	NOUN
fnp-3025	444	26	[	[	X
fnp-3025	444	27	338	338	NUM
fnp-3025	444	28	]	]	PUNCT
fnp-3025	444	29	.	.	PUNCT
fnp-3025	445	1	(	(	PUNCT
fnp-3025	445	2	genetic	genetic	ADJ
fnp-3025	445	3	knockout	knockout	NOUN
fnp-3025	445	4	of	of	ADP
fnp-3025	445	5	trem2	trem2	NOUN
fnp-3025	445	6	also	also	ADV
fnp-3025	445	7	promotes	promote	VERB
fnp-3025	445	8	the	the	DET
fnp-3025	445	9	seeded	seeded	ADJ
fnp-3025	445	10	aggregation	aggregation	NOUN
fnp-3025	445	11	and	and	CCONJ
fnp-3025	445	12	spread	spread	NOUN
fnp-3025	445	13	of	of	ADP
fnp-3025	445	14	tau	tau	PROPN
fnp-3025	445	15	in	in	ADP
fnp-3025	445	16	neuritic	neuritic	ADJ
fnp-3025	445	17	aβ	aβ	ADP
fnp-3025	445	18	plaques	plaque	NOUN
fnp-3025	445	19	[	[	X
fnp-3025	445	20	339	339	NUM
fnp-3025	445	21	]	]	PUNCT
fnp-3025	445	22	)	)	PUNCT
fnp-3025	445	23	.	.	PUNCT
fnp-3025	446	1	on	on	ADP
fnp-3025	446	2	the	the	DET
fnp-3025	446	3	other	other	ADJ
fnp-3025	446	4	hand	hand	NOUN
fnp-3025	446	5	,	,	PUNCT
fnp-3025	446	6	ultrastructural	ultrastructural	ADJ
fnp-3025	446	7	[	[	X
fnp-3025	446	8	311	311	NUM
fnp-3025	446	9	,	,	PUNCT
fnp-3025	446	10	340	340	NUM
fnp-3025	446	11	,	,	PUNCT
fnp-3025	446	12	341	341	NUM
fnp-3025	446	13	]	]	PUNCT
fnp-3025	446	14	and	and	CCONJ
fnp-3025	446	15	experimental	experimental	ADJ
fnp-3025	446	16	[	[	X
fnp-3025	446	17	342	342	NUM
fnp-3025	446	18	]	]	PUNCT
fnp-3025	446	19	investigations	investigation	NOUN
fnp-3025	446	20	have	have	AUX
fnp-3025	446	21	suggested	suggest	VERB
fnp-3025	446	22	that	that	SCONJ
fnp-3025	446	23	microglia	microglia	NOUN
fnp-3025	446	24	can	can	AUX
fnp-3025	446	25	generate	generate	VERB
fnp-3025	446	26	aβ	aβ	NOUN
fnp-3025	446	27	-	-	PUNCT
fnp-3025	446	28	amyloid	amyloid	NOUN
fnp-3025	446	29	fibrils	fibril	NOUN
fnp-3025	446	30	.	.	PUNCT
fnp-3025	447	1	in	in	ADP
fnp-3025	447	2	support	support	NOUN
fnp-3025	447	3	of	of	ADP
fnp-3025	447	4	this	this	DET
fnp-3025	447	5	hypothesis	hypothesis	NOUN
fnp-3025	447	6	,	,	PUNCT
fnp-3025	447	7	sustained	sustain	VERB
fnp-3025	447	8	pharmacologic	pharmacologic	ADJ
fnp-3025	447	9	reduction	reduction	NOUN
fnp-3025	447	10	of	of	ADP
fnp-3025	447	11	microglia	microglia	NOUN
fnp-3025	447	12	significantly	significantly	ADV
fnp-3025	447	13	diminished	diminish	VERB
fnp-3025	447	14	aβ	aβ	PRON
fnp-3025	447	15	plaque	plaque	NOUN
fnp-3025	447	16	load	load	NOUN
fnp-3025	447	17	in	in	ADP
fnp-3025	447	18	a	a	DET
fnp-3025	447	19	transgenic	transgenic	NOUN
fnp-3025	447	20	mouse	mouse	NOUN
fnp-3025	447	21	model	model	NOUN
fnp-3025	447	22	[	[	X
fnp-3025	447	23	343	343	NUM
fnp-3025	447	24	]	]	PUNCT
fnp-3025	447	25	.	.	PUNCT
fnp-3025	448	1	the	the	DET
fnp-3025	448	2	ability	ability	NOUN
fnp-3025	448	3	of	of	ADP
fnp-3025	448	4	microglia	microglia	NOUN
fnp-3025	448	5	to	to	PART
fnp-3025	448	6	assume	assume	VERB
fnp-3025	448	7	multiple	multiple	ADJ
fnp-3025	448	8	phenotypic	phenotypic	ADJ
fnp-3025	448	9	states	state	NOUN
fnp-3025	448	10	underscores	underscore	VERB
fnp-3025	448	11	the	the	DET
fnp-3025	448	12	complexity	complexity	NOUN
fnp-3025	448	13	of	of	ADP
fnp-3025	448	14	their	their	PRON
fnp-3025	448	15	participation	participation	NOUN
fnp-3025	448	16	in	in	ADP
fnp-3025	448	17	the	the	DET
fnp-3025	448	18	biology	biology	NOUN
fnp-3025	448	19	of	of	ADP
fnp-3025	448	20	aβ	aβ	DET
fnp-3025	448	21	plaques	plaque	NOUN
fnp-3025	448	22	[	[	X
fnp-3025	448	23	299	299	NUM
fnp-3025	448	24	,	,	PUNCT
fnp-3025	448	25	300	300	NUM
fnp-3025	448	26	,	,	PUNCT
fnp-3025	448	27	305	305	NUM
fnp-3025	448	28	,	,	PUNCT
fnp-3025	448	29	344	344	NUM
fnp-3025	448	30	-	-	SYM
fnp-3025	448	31	346	346	NUM
fnp-3025	448	32	]	]	PUNCT
fnp-3025	448	33	;	;	PUNCT
fnp-3025	448	34	they	they	PRON
fnp-3025	448	35	contribute	contribute	VERB
fnp-3025	448	36	to	to	ADP
fnp-3025	448	37	normal	normal	ADJ
fnp-3025	448	38	brain	brain	NOUN
fnp-3025	448	39	homeostasis	homeostasis	NOUN
fnp-3025	448	40	,	,	PUNCT
fnp-3025	448	41	but	but	CCONJ
fnp-3025	448	42	they	they	PRON
fnp-3025	448	43	also	also	ADV
fnp-3025	448	44	have	have	VERB
fnp-3025	448	45	injurious	injurious	ADJ
fnp-3025	448	46	properties	property	NOUN
fnp-3025	448	47	,	,	PUNCT
fnp-3025	448	48	particularly	particularly	ADV
fnp-3025	448	49	when	when	SCONJ
fnp-3025	448	50	activated	activate	VERB
fnp-3025	448	51	[	[	X
fnp-3025	448	52	299	299	NUM
fnp-3025	448	53	,	,	PUNCT
fnp-3025	448	54	300	300	NUM
fnp-3025	448	55	]	]	PUNCT
fnp-3025	448	56	.	.	PUNCT
fnp-3025	449	1	in	in	ADP
fnp-3025	449	2	mice	mouse	NOUN
fnp-3025	449	3	,	,	PUNCT
fnp-3025	449	4	microglia	microglia	NOUN
fnp-3025	449	5	have	have	AUX
fnp-3025	449	6	been	be	AUX
fnp-3025	449	7	found	find	VERB
fnp-3025	449	8	to	to	PART
fnp-3025	449	9	exhibit	exhibit	VERB
fnp-3025	449	10	a	a	DET
fnp-3025	449	11	range	range	NOUN
fnp-3025	449	12	of	of	ADP
fnp-3025	449	13	activation	activation	NOUN
fnp-3025	449	14	states	state	NOUN
fnp-3025	449	15	,	,	PUNCT
fnp-3025	449	16	each	each	PRON
fnp-3025	449	17	of	of	ADP
fnp-3025	449	18	which	which	PRON
fnp-3025	449	19	involves	involve	VERB
fnp-3025	449	20	the	the	DET
fnp-3025	449	21	expression	expression	NOUN
fnp-3025	449	22	of	of	ADP
fnp-3025	449	23	distinct	distinct	ADJ
fnp-3025	449	24	gene	gene	NOUN
fnp-3025	449	25	modules	module	NOUN
fnp-3025	449	26	[	[	X
fnp-3025	449	27	299	299	NUM
fnp-3025	449	28	]	]	PUNCT
fnp-3025	449	29	.	.	PUNCT
fnp-3025	450	1	microglia	microglia	NOUN
fnp-3025	450	2	become	become	VERB
fnp-3025	450	3	activated	activate	VERB
fnp-3025	450	4	in	in	ADP
fnp-3025	450	5	the	the	DET
fnp-3025	450	6	presence	presence	NOUN
fnp-3025	450	7	of	of	ADP
fnp-3025	450	8	aggregated	aggregated	ADJ
fnp-3025	450	9	aβ	aβ	NOUN
fnp-3025	450	10	,	,	PUNCT
fnp-3025	450	11	and	and	CCONJ
fnp-3025	450	12	in	in	ADP
fnp-3025	450	13	this	this	DET
fnp-3025	450	14	condition	condition	NOUN
fnp-3025	450	15	they	they	PRON
fnp-3025	450	16	can	can	AUX
fnp-3025	450	17	harm	harm	VERB
fnp-3025	450	18	the	the	DET
fnp-3025	450	19	brain	brain	NOUN
fnp-3025	450	20	both	both	CCONJ
fnp-3025	450	21	through	through	ADP
fnp-3025	450	22	the	the	DET
fnp-3025	450	23	secretion	secretion	NOUN
fnp-3025	450	24	of	of	ADP
fnp-3025	450	25	pro	pro	ADJ
fnp-3025	450	26	-	-	ADJ
fnp-3025	450	27	inflammatory	inflammatory	ADJ
fnp-3025	450	28	agents	agent	NOUN
fnp-3025	450	29	and	and	CCONJ
fnp-3025	450	30	the	the	DET
fnp-3025	450	31	elimination	elimination	NOUN
fnp-3025	450	32	of	of	ADP
fnp-3025	450	33	synapses	synapsis	NOUN
fnp-3025	450	34	[	[	X
fnp-3025	450	35	300	300	NUM
fnp-3025	450	36	]	]	PUNCT
fnp-3025	450	37	.	.	PUNCT
fnp-3025	451	1	to	to	PART
fnp-3025	451	2	complicate	complicate	VERB
fnp-3025	451	3	matters	matter	NOUN
fnp-3025	451	4	further	far	ADV
fnp-3025	451	5	,	,	PUNCT
fnp-3025	451	6	a	a	DET
fnp-3025	451	7	variety	variety	NOUN
fnp-3025	451	8	of	of	ADP
fnp-3025	451	9	microglial	microglial	ADJ
fnp-3025	451	10	phenotypes	phenotype	NOUN
fnp-3025	451	11	are	be	AUX
fnp-3025	451	12	simultaneously	simultaneously	ADV
fnp-3025	451	13	present	present	ADJ
fnp-3025	451	14	within	within	ADP
fnp-3025	451	15	the	the	DET
fnp-3025	451	16	same	same	ADJ
fnp-3025	451	17	brain	brain	NOUN
fnp-3025	452	1	[	[	X
fnp-3025	452	2	345	345	NUM
fnp-3025	452	3	]	]	PUNCT
fnp-3025	452	4	,	,	PUNCT
fnp-3025	452	5	and	and	CCONJ
fnp-3025	452	6	the	the	DET
fnp-3025	452	7	involvement	involvement	NOUN
fnp-3025	452	8	of	of	ADP
fnp-3025	452	9	microglia	microglia	NOUN
fnp-3025	452	10	in	in	ADP
fnp-3025	452	11	plaques	plaque	NOUN
fnp-3025	452	12	differs	differ	VERB
fnp-3025	452	13	as	as	ADP
fnp-3025	452	14	a	a	DET
fnp-3025	452	15	function	function	NOUN
fnp-3025	452	16	of	of	ADP
fnp-3025	452	17	age	age	NOUN
fnp-3025	452	18	and	and	CCONJ
fnp-3025	452	19	disease	disease	NOUN
fnp-3025	452	20	stage	stage	NOUN
fnp-3025	452	21	[	[	X
fnp-3025	452	22	299	299	NUM
fnp-3025	452	23	]	]	PUNCT
fnp-3025	452	24	.	.	PUNCT
fnp-3025	453	1	finally	finally	ADV
fnp-3025	453	2	,	,	PUNCT
fnp-3025	453	3	while	while	SCONJ
fnp-3025	453	4	the	the	DET
fnp-3025	453	5	discovery	discovery	NOUN
fnp-3025	453	6	of	of	ADP
fnp-3025	453	7	microglial	microglial	ADJ
fnp-3025	453	8	risk	risk	NOUN
fnp-3025	453	9	factors	factor	NOUN
fnp-3025	453	10	for	for	ADP
fnp-3025	453	11	ad	ad	NOUN
fnp-3025	453	12	emerged	emerge	VERB
fnp-3025	453	13	from	from	ADP
fnp-3025	453	14	human	human	ADJ
fnp-3025	453	15	genetic	genetic	ADJ
fnp-3025	453	16	analyses	analysis	NOUN
fnp-3025	453	17	[	[	X
fnp-3025	453	18	306	306	NUM
fnp-3025	453	19	]	]	PUNCT
fnp-3025	453	20	,	,	PUNCT
fnp-3025	453	21	we	we	PRON
fnp-3025	453	22	know	know	VERB
fnp-3025	453	23	far	far	ADV
fnp-3025	453	24	more	more	ADV
fnp-3025	453	25	about	about	ADP
fnp-3025	453	26	microglia	microglia	NOUN
fnp-3025	453	27	in	in	ADP
fnp-3025	453	28	rodent	rodent	ADJ
fnp-3025	453	29	models	model	NOUN
fnp-3025	453	30	than	than	ADP
fnp-3025	453	31	in	in	ADP
fnp-3025	453	32	human	human	ADJ
fnp-3025	453	33	ad	ad	NOUN
fnp-3025	453	34	,	,	PUNCT
fnp-3025	453	35	and	and	CCONJ
fnp-3025	453	36	current	current	ADJ
fnp-3025	453	37	evidence	evidence	NOUN
fnp-3025	453	38	suggests	suggest	VERB
fnp-3025	453	39	that	that	SCONJ
fnp-3025	453	40	there	there	PRON
fnp-3025	453	41	are	be	VERB
fnp-3025	453	42	important	important	ADJ
fnp-3025	453	43	differences	difference	NOUN
fnp-3025	453	44	that	that	PRON
fnp-3025	453	45	can	can	AUX
fnp-3025	453	46	not	not	PART
fnp-3025	453	47	be	be	AUX
fnp-3025	453	48	overlooked	overlook	VERB
fnp-3025	453	49	[	[	X
fnp-3025	453	50	299	299	NUM
fnp-3025	453	51	,	,	PUNCT
fnp-3025	453	52	347	347	NUM
fnp-3025	453	53	-	-	SYM
fnp-3025	453	54	349	349	NUM
fnp-3025	453	55	]	]	PUNCT
fnp-3025	453	56	.	.	PUNCT
fnp-3025	454	1	these	these	DET
fnp-3025	454	2	findings	finding	NOUN
fnp-3025	454	3	collectively	collectively	ADV
fnp-3025	454	4	highlight	highlight	VERB
fnp-3025	454	5	the	the	DET
fnp-3025	454	6	challenges	challenge	NOUN
fnp-3025	454	7	presented	present	VERB
fnp-3025	454	8	by	by	ADP
fnp-3025	454	9	microglia	microglia	NOUN
fnp-3025	454	10	as	as	ADP
fnp-3025	454	11	therapeutic	therapeutic	ADJ
fnp-3025	454	12	targets	target	NOUN
fnp-3025	454	13	in	in	ADP
fnp-3025	454	14	ad	ad	NOUN
fnp-3025	454	15	.	.	PUNCT
fnp-3025	455	1	figure	figure	NOUN
fnp-3025	455	2	20	20	NUM
fnp-3025	455	3	.	.	PUNCT
fnp-3025	455	4	electron	electron	NOUN
fnp-3025	455	5	micrographs	micrograph	NOUN
fnp-3025	455	6	of	of	ADP
fnp-3025	455	7	a	a	DET
fnp-3025	455	8	microglial	microglial	ADJ
fnp-3025	455	9	cell	cell	NOUN
fnp-3025	455	10	in	in	ADP
fnp-3025	455	11	an	an	DET
fnp-3025	455	12	aβ	aβ	NOUN
fnp-3025	455	13	-	-	PUNCT
fnp-3025	455	14	amyloid	amyloid	NOUN
fnp-3025	455	15	plaque	plaque	NOUN
fnp-3025	455	16	of	of	ADP
fnp-3025	455	17	an	an	DET
fnp-3025	455	18	ad	ad	NOUN
fnp-3025	455	19	patient	patient	NOUN
fnp-3025	455	20	.	.	PUNCT
fnp-3025	456	1	the	the	DET
fnp-3025	456	2	white	white	PROPN
fnp-3025	456	3	box	box	PROPN
fnp-3025	456	4	in	in	ADP
fnp-3025	456	5	the	the	DET
fnp-3025	456	6	image	image	NOUN
fnp-3025	456	7	on	on	ADP
fnp-3025	456	8	the	the	DET
fnp-3025	456	9	left	left	ADJ
fnp-3025	456	10	denotes	denote	VERB
fnp-3025	456	11	the	the	DET
fnp-3025	456	12	region	region	NOUN
fnp-3025	456	13	at	at	ADP
fnp-3025	456	14	higher	high	ADJ
fnp-3025	456	15	magnification	magnification	NOUN
fnp-3025	456	16	on	on	ADP
fnp-3025	456	17	the	the	DET
fnp-3025	456	18	right	right	NOUN
fnp-3025	456	19	.	.	PUNCT
fnp-3025	457	1	the	the	DET
fnp-3025	457	2	fibrillar	fibrillar	ADJ
fnp-3025	457	3	bundles	bundle	NOUN
fnp-3025	457	4	of	of	ADP
fnp-3025	457	5	aβ	aβ	NOUN
fnp-3025	457	6	interdigitate	interdigitate	NOUN
fnp-3025	457	7	with	with	ADP
fnp-3025	457	8	the	the	DET
fnp-3025	457	9	microglial	microglial	ADJ
fnp-3025	457	10	soma	soma	NOUN
fnp-3025	457	11	.	.	PUNCT
fnp-3025	458	1	note	note	VERB
fnp-3025	458	2	that	that	SCONJ
fnp-3025	458	3	the	the	DET
fnp-3025	458	4	microglial	microglial	ADJ
fnp-3025	458	5	cytoplasm	cytoplasm	NOUN
fnp-3025	458	6	appears	appear	VERB
fnp-3025	458	7	artifactually	artifactually	ADV
fnp-3025	458	8	rarefied	rarefy	VERB
fnp-3025	458	9	in	in	ADP
fnp-3025	458	10	this	this	DET
fnp-3025	458	11	autopsy	autopsy	ADJ
fnp-3025	458	12	-	-	PUNCT
fnp-3025	458	13	derived	derive	VERB
fnp-3025	458	14	tissue	tissue	NOUN
fnp-3025	458	15	.	.	PUNCT
fnp-3025	459	1	bar	bar	NOUN
fnp-3025	459	2	=	=	SYM
fnp-3025	459	3	500	500	NUM
fnp-3025	459	4	nm	nm	NOUN
fnp-3025	459	5	(	(	PUNCT
fnp-3025	459	6	right	right	NOUN
fnp-3025	459	7	)	)	PUNCT
fnp-3025	459	8	,	,	PUNCT
fnp-3025	459	9	2.8μm	2.8μm	NUM
fnp-3025	459	10	(	(	PUNCT
fnp-3025	459	11	left	leave	VERB
fnp-3025	459	12	)	)	PUNCT
fnp-3025	459	13	.	.	PUNCT
fnp-3025	460	1	6.2.2	6.2.2	NUM
fnp-3025	460	2	astrocytes	astrocyte	VERB
fnp-3025	460	3	in	in	ADP
fnp-3025	460	4	the	the	DET
fnp-3025	460	5	vicinity	vicinity	NOUN
fnp-3025	460	6	of	of	ADP
fnp-3025	460	7	many	many	ADJ
fnp-3025	460	8	aβ	aβ	NOUN
fnp-3025	460	9	-	-	PUNCT
fnp-3025	460	10	amyloid	amyloid	NOUN
fnp-3025	460	11	plaques	plaque	NOUN
fnp-3025	460	12	,	,	PUNCT
fnp-3025	460	13	astrocytes	astrocyte	VERB
fnp-3025	460	14	hypertrophy	hypertrophy	NOUN
fnp-3025	460	15	and	and	CCONJ
fnp-3025	460	16	increase	increase	VERB
fnp-3025	460	17	their	their	PRON
fnp-3025	460	18	expression	expression	NOUN
fnp-3025	460	19	of	of	ADP
fnp-3025	460	20	glial	glial	ADJ
fnp-3025	460	21	fibrillary	fibrillary	ADJ
fnp-3025	460	22	acidic	acidic	ADJ
fnp-3025	460	23	protein	protein	NOUN
fnp-3025	460	24	(	(	PUNCT
fnp-3025	460	25	gfap	gfap	ADJ
fnp-3025	460	26	)	)	PUNCT
fnp-3025	461	1	[	[	X
fnp-3025	461	2	316	316	NUM
fnp-3025	461	3	]	]	PUNCT
fnp-3025	461	4	(	(	PUNCT
fnp-3025	461	5	figure	figure	NOUN
fnp-3025	461	6	19	19	NUM
fnp-3025	461	7	)	)	PUNCT
fnp-3025	461	8	.	.	PUNCT
fnp-3025	462	1	the	the	DET
fnp-3025	462	2	degree	degree	NOUN
fnp-3025	462	3	of	of	ADP
fnp-3025	462	4	astrocytic	astrocytic	ADJ
fnp-3025	462	5	hypertrophy	hypertrophy	NOUN
fnp-3025	462	6	surrounding	surround	VERB
fnp-3025	462	7	plaques	plaque	NOUN
fnp-3025	462	8	,	,	PUNCT
fnp-3025	462	9	however	however	ADV
fnp-3025	462	10	,	,	PUNCT
fnp-3025	462	11	is	be	AUX
fnp-3025	462	12	inconsistent	inconsistent	ADJ
fnp-3025	462	13	[	[	X
fnp-3025	462	14	317	317	NUM
fnp-3025	462	15	]	]	PUNCT
fnp-3025	462	16	.	.	PUNCT
fnp-3025	463	1	gfap	gfap	ADJ
fnp-3025	463	2	expression	expression	NOUN
fnp-3025	463	3	is	be	AUX
fnp-3025	463	4	a	a	DET
fnp-3025	463	5	reasonably	reasonably	ADV
fnp-3025	463	6	reliable	reliable	ADJ
fnp-3025	463	7	index	index	NOUN
fnp-3025	463	8	of	of	ADP
fnp-3025	463	9	astrocytic	astrocytic	ADJ
fnp-3025	463	10	reactivity	reactivity	NOUN
fnp-3025	463	11	,	,	PUNCT
fnp-3025	463	12	but	but	CCONJ
fnp-3025	463	13	gfap	gfap	NOUN
fnp-3025	463	14	is	be	AUX
fnp-3025	463	15	not	not	PART
fnp-3025	463	16	detectable	detectable	ADJ
fnp-3025	463	17	in	in	ADP
fnp-3025	463	18	many	many	ADJ
fnp-3025	463	19	healthy	healthy	ADJ
fnp-3025	463	20	astrocytes	astrocyte	NOUN
fnp-3025	463	21	,	,	PUNCT
fnp-3025	463	22	and	and	CCONJ
fnp-3025	463	23	its	its	PRON
fnp-3025	463	24	expression	expression	NOUN
fnp-3025	463	25	varies	vary	VERB
fnp-3025	463	26	in	in	ADP
fnp-3025	463	27	different	different	ADJ
fnp-3025	463	28	parts	part	NOUN
fnp-3025	463	29	of	of	ADP
fnp-3025	463	30	the	the	DET
fnp-3025	463	31	brain	brain	NOUN
fnp-3025	463	32	,	,	PUNCT
fnp-3025	463	33	in	in	ADP
fnp-3025	463	34	different	different	ADJ
fnp-3025	463	35	animal	animal	NOUN
fnp-3025	463	36	species	specie	NOUN
fnp-3025	463	37	,	,	PUNCT
fnp-3025	463	38	and	and	CCONJ
fnp-3025	463	39	as	as	ADP
fnp-3025	463	40	a	a	DET
fnp-3025	463	41	function	function	NOUN
fnp-3025	463	42	of	of	ADP
fnp-3025	463	43	age.13	age.13	PRON
fnp-3025	463	44	compared	compare	VERB
fnp-3025	463	45	to	to	ADP
fnp-3025	463	46	microglia	microglia	ADJ
fnp-3025	463	47	,	,	PUNCT
fnp-3025	463	48	astrocytic	astrocytic	ADJ
fnp-3025	463	49	somata	somata	NOUN
fnp-3025	463	50	tend	tend	VERB
fnp-3025	463	51	to	to	PART
fnp-3025	463	52	localize	localize	VERB
fnp-3025	463	53	more	more	ADV
fnp-3025	463	54	peripherally	peripherally	ADV
fnp-3025	463	55	to	to	ADP
fnp-3025	463	56	the	the	DET
fnp-3025	463	57	aggregated	aggregate	VERB
fnp-3025	463	58	aβ	aβ	NOUN
fnp-3025	463	59	in	in	ADP
fnp-3025	463	60	plaques	plaque	NOUN
fnp-3025	463	61	[	[	X
fnp-3025	463	62	175	175	NUM
fnp-3025	463	63	,	,	PUNCT
fnp-3025	463	64	302	302	NUM
fnp-3025	463	65	,	,	PUNCT
fnp-3025	463	66	311	311	NUM
fnp-3025	463	67	,	,	PUNCT
fnp-3025	463	68	313	313	NUM
fnp-3025	463	69	,	,	PUNCT
fnp-3025	463	70	327	327	NUM
fnp-3025	463	71	,	,	PUNCT
fnp-3025	463	72	330	330	NUM
fnp-3025	463	73	]	]	PUNCT
fnp-3025	463	74	,	,	PUNCT
fnp-3025	463	75	whence	whence	SCONJ
fnp-3025	463	76	their	their	PRON
fnp-3025	463	77	processes	process	NOUN
fnp-3025	463	78	penetrate	penetrate	VERB
fnp-3025	463	79	and	and	CCONJ
fnp-3025	463	80	to	to	ADP
fnp-3025	463	81	some	some	DET
fnp-3025	463	82	extent	extent	NOUN
fnp-3025	463	83	encapsulate	encapsulate	VERB
fnp-3025	463	84	the	the	DET
fnp-3025	463	85	plaques	plaque	NOUN
fnp-3025	463	86	(	(	PUNCT
fnp-3025	463	87	figure	figure	NOUN
fnp-3025	463	88	19	19	NUM
fnp-3025	463	89	)	)	PUNCT
fnp-3025	463	90	.	.	PUNCT
fnp-3025	464	1	despite	despite	SCONJ
fnp-3025	464	2	their	their	PRON
fnp-3025	464	3	tendency	tendency	NOUN
fnp-3025	464	4	to	to	PART
fnp-3025	464	5	partially	partially	ADV
fnp-3025	464	6	segregate	segregate	VERB
fnp-3025	464	7	,	,	PUNCT
fnp-3025	464	8	astrocytes	astrocyte	NOUN
fnp-3025	464	9	and	and	CCONJ
fnp-3025	464	10	microglia	microglia	NOUN
fnp-3025	464	11	show	show	VERB
fnp-3025	464	12	some	some	DET
fnp-3025	464	13	spatial	spatial	ADJ
fnp-3025	464	14	overlap	overlap	NOUN
fnp-3025	464	15	,	,	PUNCT
fnp-3025	464	16	and	and	CCONJ
fnp-3025	464	17	physical	physical	ADJ
fnp-3025	464	18	and	and	CCONJ
fnp-3025	464	19	chemical	chemical	ADJ
fnp-3025	464	20	interactions	interaction	NOUN
fnp-3025	464	21	between	between	ADP
fnp-3025	464	22	them	they	PRON
fnp-3025	464	23	help	help	VERB
fnp-3025	464	24	to	to	PART
fnp-3025	464	25	define	define	VERB
fnp-3025	464	26	the	the	DET
fnp-3025	464	27	inflammatory	inflammatory	ADJ
fnp-3025	464	28	state	state	NOUN
fnp-3025	464	29	of	of	ADP
fnp-3025	464	30	plaques	plaque	NOUN
fnp-3025	464	31	[	[	X
fnp-3025	464	32	304	304	NUM
fnp-3025	464	33	]	]	PUNCT
fnp-3025	464	34	.	.	PUNCT
fnp-3025	465	1	activated	activate	VERB
fnp-3025	465	2	astrocytes	astrocyte	NOUN
fnp-3025	465	3	promote	promote	VERB
fnp-3025	465	4	the	the	DET
fnp-3025	465	5	inflammatory	inflammatory	ADJ
fnp-3025	465	6	milieu	milieu	NOUN
fnp-3025	465	7	around	around	ADP
fnp-3025	465	8	plaques	plaque	NOUN
fnp-3025	465	9	through	through	ADP
fnp-3025	465	10	the	the	DET
fnp-3025	465	11	generation	generation	NOUN
fnp-3025	465	12	of	of	ADP
fnp-3025	465	13	pro	pro	ADJ
fnp-3025	465	14	-	-	ADJ
fnp-3025	465	15	inflammatory	inflammatory	ADJ
fnp-3025	465	16	substances	substance	NOUN
fnp-3025	465	17	,	,	PUNCT
fnp-3025	465	18	including	include	VERB
fnp-3025	465	19	cytokines	cytokine	NOUN
fnp-3025	465	20	/	/	SYM
fnp-3025	465	21	chemokines	chemokine	NOUN
fnp-3025	465	22	,	,	PUNCT
fnp-3025	465	23	activation	activation	NOUN
fnp-3025	465	24	of	of	ADP
fnp-3025	465	25	the	the	DET
fnp-3025	465	26	complement	complement	NOUN
fnp-3025	465	27	cascade	cascade	NOUN
fnp-3025	465	28	,	,	PUNCT
fnp-3025	465	29	and	and	CCONJ
fnp-3025	465	30	reactive	reactive	ADJ
fnp-3025	465	31	nitrogen	nitrogen	NOUN
fnp-3025	465	32	and	and	CCONJ
fnp-3025	465	33	oxygen	oxygen	NOUN
fnp-3025	465	34	species	specie	NOUN
fnp-3025	465	35	[	[	X
fnp-3025	465	36	316	316	NUM
fnp-3025	465	37	]	]	PUNCT
fnp-3025	465	38	.	.	PUNCT
fnp-3025	466	1	as	as	ADP
fnp-3025	466	2	in	in	ADP
fnp-3025	466	3	the	the	DET
fnp-3025	466	4	case	case	NOUN
fnp-3025	466	5	of	of	ADP
fnp-3025	466	6	microglia	microglia	NOUN
fnp-3025	466	7	,	,	PUNCT
fnp-3025	466	8	the	the	DET
fnp-3025	466	9	role	role	NOUN
fnp-3025	466	10	of	of	ADP
fnp-3025	466	11	astrocytes	astrocyte	NOUN
fnp-3025	466	12	in	in	ADP
fnp-3025	466	13	neurodegeneration	neurodegeneration	NOUN
fnp-3025	466	14	is	be	AUX
fnp-3025	466	15	complicated	complicate	VERB
fnp-3025	466	16	by	by	ADP
fnp-3025	466	17	their	their	PRON
fnp-3025	466	18	variable	variable	NOUN
fnp-3025	466	19	and	and	CCONJ
fnp-3025	466	20	sometimes	sometimes	ADV
fnp-3025	466	21	paradoxical	paradoxical	ADJ
fnp-3025	466	22	phenotypes	phenotype	NOUN
fnp-3025	466	23	[	[	X
fnp-3025	466	24	317	317	NUM
fnp-3025	466	25	]	]	PUNCT
fnp-3025	466	26	.	.	PUNCT
fnp-3025	467	1	in	in	ADP
fnp-3025	467	2	ad	ad	NOUN
fnp-3025	467	3	,	,	PUNCT
fnp-3025	467	4	astrocytes	astrocyte	NOUN
fnp-3025	467	5	can	can	AUX
fnp-3025	467	6	both	both	PRON
fnp-3025	467	7	gain	gain	VERB
fnp-3025	467	8	a	a	DET
fnp-3025	467	9	toxic	toxic	ADJ
fnp-3025	467	10	function	function	NOUN
fnp-3025	467	11	and	and	CCONJ
fnp-3025	467	12	lose	lose	VERB
fnp-3025	467	13	their	their	PRON
fnp-3025	467	14	normal	normal	ADJ
fnp-3025	467	15	physiologic	physiologic	ADJ
fnp-3025	467	16	function	function	NOUN
fnp-3025	467	17	[	[	X
fnp-3025	467	18	316	316	NUM
fnp-3025	467	19	,	,	PUNCT
fnp-3025	467	20	350	350	NUM
fnp-3025	467	21	,	,	PUNCT
fnp-3025	467	22	351	351	NUM
fnp-3025	467	23	]	]	PUNCT
fnp-3025	467	24	.	.	PUNCT
fnp-3025	468	1	astrocytes	astrocyte	NOUN
fnp-3025	468	2	have	have	AUX
fnp-3025	468	3	been	be	AUX
fnp-3025	468	4	shown	show	VERB
fnp-3025	468	5	experimentally	experimentally	ADV
fnp-3025	468	6	to	to	PART
fnp-3025	468	7	take	take	VERB
fnp-3025	468	8	up	up	ADP
fnp-3025	468	9	and	and	CCONJ
fnp-3025	468	10	degrade	degrade	VERB
fnp-3025	468	11	aβ	aβ	PRON
fnp-3025	468	12	[	[	X
fnp-3025	468	13	315	315	NUM
fnp-3025	468	14	]	]	PUNCT
fnp-3025	468	15	.	.	PUNCT
fnp-3025	469	1	they	they	PRON
fnp-3025	469	2	also	also	ADV
fnp-3025	469	3	are	be	AUX
fnp-3025	469	4	capable	capable	ADJ
fnp-3025	469	5	of	of	ADP
fnp-3025	469	6	expressing	express	VERB
fnp-3025	469	7	aβ	aβ	PRON
fnp-3025	470	1	[	[	X
fnp-3025	470	2	352	352	NUM
fnp-3025	470	3	]	]	PUNCT
fnp-3025	470	4	,	,	PUNCT
fnp-3025	470	5	and	and	CCONJ
fnp-3025	470	6	astrocytes	astrocyte	NOUN
fnp-3025	470	7	containing	contain	VERB
fnp-3025	470	8	ample	ample	ADJ
fnp-3025	470	9	aβ	aβ	NOUN
fnp-3025	470	10	are	be	AUX
fnp-3025	470	11	present	present	ADJ
fnp-3025	470	12	in	in	ADP
fnp-3025	470	13	the	the	DET
fnp-3025	470	14	alzheimeric	alzheimeric	ADJ
fnp-3025	470	15	brain	brain	NOUN
fnp-3025	471	1	[	[	X
fnp-3025	471	2	186	186	NUM
fnp-3025	471	3	,	,	PUNCT
fnp-3025	471	4	316	316	NUM
fnp-3025	471	5	,	,	PUNCT
fnp-3025	471	6	353	353	NUM
fnp-3025	471	7	,	,	PUNCT
fnp-3025	471	8	354	354	NUM
fnp-3025	471	9	]	]	PUNCT
fnp-3025	471	10	(	(	PUNCT
fnp-3025	471	11	figure	figure	NOUN
fnp-3025	471	12	8)	8)	NUM
fnp-3025	471	13	.	.	PUNCT
fnp-3025	472	1	in	in	ADP
fnp-3025	472	2	addition	addition	NOUN
fnp-3025	472	3	,	,	PUNCT
fnp-3025	472	4	the	the	DET
fnp-3025	472	5	extent	extent	NOUN
fnp-3025	472	6	of	of	ADP
fnp-3025	472	7	peri	peri	NOUN
fnp-3025	472	8	-	-	PUNCT
fnp-3025	472	9	plaque	plaque	NOUN
fnp-3025	472	10	reactive	reactive	NOUN
fnp-3025	472	11	astrocytosis	astrocytosis	NOUN
fnp-3025	472	12	is	be	AUX
fnp-3025	472	13	positively	positively	ADV
fnp-3025	472	14	correlated	correlate	VERB
fnp-3025	472	15	with	with	ADP
fnp-3025	472	16	cognitive	cognitive	ADJ
fnp-3025	472	17	status	status	NOUN
fnp-3025	472	18	in	in	ADP
fnp-3025	472	19	aged	aged	ADJ
fnp-3025	472	20	subjects	subject	NOUN
fnp-3025	472	21	,	,	PUNCT
fnp-3025	472	22	and	and	CCONJ
fnp-3025	472	23	their	their	PRON
fnp-3025	472	24	abundance	abundance	NOUN
fnp-3025	472	25	is	be	AUX
fnp-3025	472	26	reduced	reduce	VERB
fnp-3025	472	27	in	in	ADP
fnp-3025	472	28	persons	person	NOUN
fnp-3025	472	29	expressing	express	VERB
fnp-3025	472	30	apolipoprotein	apolipoprotein	ADJ
fnp-3025	472	31	e4	e4	PROPN
fnp-3025	472	32	,	,	PUNCT
fnp-3025	472	33	a	a	DET
fnp-3025	472	34	major	major	ADJ
fnp-3025	472	35	risk	risk	NOUN
fnp-3025	472	36	factor	factor	NOUN
fnp-3025	472	37	for	for	ADP
fnp-3025	472	38	ad	ad	NOUN
fnp-3025	472	39	[	[	X
fnp-3025	472	40	316	316	NUM
fnp-3025	472	41	]	]	PUNCT
fnp-3025	472	42	.	.	PUNCT
fnp-3025	473	1	in	in	ADP
fnp-3025	473	2	summary	summary	NOUN
fnp-3025	473	3	,	,	PUNCT
fnp-3025	473	4	research	research	NOUN
fnp-3025	473	5	on	on	ADP
fnp-3025	473	6	microglia	microglia	NOUN
fnp-3025	473	7	and	and	CCONJ
fnp-3025	473	8	astrocytes	astrocyte	NOUN
fnp-3025	473	9	has	have	AUX
fnp-3025	473	10	disclosed	disclose	VERB
fnp-3025	473	11	the	the	DET
fnp-3025	473	12	extraordinary	extraordinary	ADJ
fnp-3025	473	13	malleability	malleability	NOUN
fnp-3025	473	14	of	of	ADP
fnp-3025	473	15	these	these	DET
fnp-3025	473	16	glial	glial	ADJ
fnp-3025	473	17	cells	cell	NOUN
fnp-3025	473	18	,	,	PUNCT
fnp-3025	473	19	the	the	DET
fnp-3025	473	20	complexity	complexity	NOUN
fnp-3025	473	21	of	of	ADP
fnp-3025	473	22	their	their	PRON
fnp-3025	473	23	involvement	involvement	NOUN
fnp-3025	473	24	in	in	ADP
fnp-3025	473	25	plaques	plaque	NOUN
fnp-3025	473	26	,	,	PUNCT
fnp-3025	473	27	and	and	CCONJ
fnp-3025	473	28	thus	thus	ADV
fnp-3025	473	29	the	the	DET
fnp-3025	473	30	attendant	attendant	ADJ
fnp-3025	473	31	difficulties	difficulty	NOUN
fnp-3025	473	32	in	in	ADP
fnp-3025	473	33	targeting	target	VERB
fnp-3025	473	34	them	they	PRON
fnp-3025	473	35	therapeutically	therapeutically	ADV
fnp-3025	473	36	.	.	PUNCT
fnp-3025	474	1	interventions	intervention	NOUN
fnp-3025	474	2	that	that	PRON
fnp-3025	474	3	modulate	modulate	VERB
fnp-3025	474	4	the	the	DET
fnp-3025	474	5	activity	activity	NOUN
fnp-3025	474	6	of	of	ADP
fnp-3025	474	7	glia	glia	NOUN
fnp-3025	474	8	could	could	AUX
fnp-3025	474	9	either	either	CCONJ
fnp-3025	474	10	promote	promote	VERB
fnp-3025	474	11	or	or	CCONJ
fnp-3025	474	12	hinder	hinder	VERB
fnp-3025	474	13	disease	disease	NOUN
fnp-3025	474	14	progression	progression	NOUN
fnp-3025	474	15	,	,	PUNCT
fnp-3025	474	16	depending	depend	VERB
fnp-3025	474	17	on	on	ADP
fnp-3025	474	18	the	the	DET
fnp-3025	474	19	state	state	NOUN
fnp-3025	474	20	of	of	ADP
fnp-3025	474	21	the	the	DET
fnp-3025	474	22	cells	cell	NOUN
fnp-3025	474	23	in	in	ADP
fnp-3025	474	24	different	different	ADJ
fnp-3025	474	25	brain	brain	NOUN
fnp-3025	474	26	areas	area	NOUN
fnp-3025	474	27	,	,	PUNCT
fnp-3025	474	28	their	their	PRON
fnp-3025	474	29	relative	relative	ADJ
fnp-3025	474	30	abundance	abundance	NOUN
fnp-3025	474	31	,	,	PUNCT
fnp-3025	474	32	and	and	CCONJ
fnp-3025	474	33	the	the	DET
fnp-3025	474	34	timing	timing	NOUN
fnp-3025	474	35	of	of	ADP
fnp-3025	474	36	therapeutic	therapeutic	ADJ
fnp-3025	474	37	delivery	delivery	NOUN
fnp-3025	474	38	in	in	ADP
fnp-3025	474	39	the	the	DET
fnp-3025	474	40	protracted	protract	VERB
fnp-3025	474	41	course	course	NOUN
fnp-3025	474	42	of	of	ADP
fnp-3025	474	43	ad	ad	NOUN
fnp-3025	474	44	.	.	PUNCT
fnp-3025	475	1	nevertheless	nevertheless	ADV
fnp-3025	475	2	,	,	PUNCT
fnp-3025	475	3	the	the	DET
fnp-3025	475	4	obvious	obvious	ADJ
fnp-3025	475	5	importance	importance	NOUN
fnp-3025	475	6	of	of	ADP
fnp-3025	475	7	microglia	microglia	NOUN
fnp-3025	475	8	and	and	CCONJ
fnp-3025	475	9	astrocytes	astrocyte	NOUN
fnp-3025	475	10	in	in	ADP
fnp-3025	475	11	the	the	DET
fnp-3025	475	12	pathobiology	pathobiology	NOUN
fnp-3025	475	13	of	of	ADP
fnp-3025	475	14	ad	ad	NOUN
fnp-3025	475	15	justifies	justify	VERB
fnp-3025	475	16	continued	continued	ADJ
fnp-3025	475	17	efforts	effort	NOUN
fnp-3025	475	18	to	to	PART
fnp-3025	475	19	decipher	decipher	VERB
fnp-3025	475	20	the	the	DET
fnp-3025	475	21	mechanisms	mechanism	NOUN
fnp-3025	475	22	by	by	ADP
fnp-3025	475	23	which	which	PRON
fnp-3025	475	24	they	they	PRON
fnp-3025	475	25	interact	interact	VERB
fnp-3025	475	26	with	with	ADP
fnp-3025	475	27	aβ	aβ	NOUN
fnp-3025	475	28	and	and	CCONJ
fnp-3025	475	29	with	with	ADP
fnp-3025	475	30	the	the	DET
fnp-3025	475	31	other	other	ADJ
fnp-3025	475	32	cellular	cellular	ADJ
fnp-3025	475	33	components	component	NOUN
fnp-3025	475	34	of	of	ADP
fnp-3025	475	35	plaques	plaque	NOUN
fnp-3025	475	36	.	.	PUNCT
fnp-3025	476	1	for	for	ADP
fnp-3025	476	2	additional	additional	ADJ
fnp-3025	476	3	reviews	review	NOUN
fnp-3025	476	4	of	of	ADP
fnp-3025	476	5	microglia	microglia	NOUN
fnp-3025	476	6	and	and	CCONJ
fnp-3025	476	7	astrocytes	astrocyte	NOUN
fnp-3025	476	8	in	in	ADP
fnp-3025	476	9	aging	aging	NOUN
fnp-3025	476	10	and	and	CCONJ
fnp-3025	476	11	ad	ad	NOUN
fnp-3025	476	12	,	,	PUNCT
fnp-3025	476	13	see	see	VERB
fnp-3025	476	14	[	[	X
fnp-3025	476	15	312	312	NUM
fnp-3025	476	16	,	,	PUNCT
fnp-3025	476	17	355	355	NUM
fnp-3025	476	18	-	-	SYM
fnp-3025	476	19	357	357	NUM
fnp-3025	476	20	]	]	PUNCT
fnp-3025	476	21	.	.	PUNCT
fnp-3025	477	1	13	13	NUM
fnp-3025	478	1	the	the	DET
fnp-3025	478	2	authors	author	NOUN
fnp-3025	478	3	note	note	VERB
fnp-3025	478	4	that	that	SCONJ
fnp-3025	478	5	the	the	DET
fnp-3025	478	6	findings	finding	NOUN
fnp-3025	478	7	should	should	AUX
fnp-3025	478	8	be	be	AUX
fnp-3025	478	9	interpreted	interpret	VERB
fnp-3025	478	10	cautiously	cautiously	ADV
fnp-3025	478	11	in	in	ADP
fnp-3025	478	12	light	light	NOUN
fnp-3025	478	13	of	of	ADP
fnp-3025	478	14	the	the	DET
fnp-3025	478	15	pitfalls	pitfall	NOUN
fnp-3025	478	16	associated	associate	VERB
fnp-3025	478	17	with	with	ADP
fnp-3025	478	18	histochemical	histochemical	ADJ
fnp-3025	478	19	methods	method	NOUN
fnp-3025	478	20	(	(	PUNCT
fnp-3025	478	21	garwood	garwood	PROPN
fnp-3025	478	22	et	et	PROPN
fnp-3025	478	23	al	al	PROPN
fnp-3025	478	24	.	.	PUNCT
fnp-3025	479	1	[	[	X
fnp-3025	479	2	2017	2017	NUM
fnp-3025	479	3	]	]	PUNCT
fnp-3025	480	1	[	[	X
fnp-3025	480	2	reference	reference	NOUN
fnp-3025	480	3	316	316	NUM
fnp-3025	480	4	]	]	PUNCT
fnp-3025	480	5	)	)	PUNCT
fnp-3025	480	6	.	.	PUNCT
fnp-3025	481	1	this	this	DET
fnp-3025	481	2	advice	advice	NOUN
fnp-3025	481	3	applies	apply	VERB
fnp-3025	481	4	to	to	ADP
fnp-3025	481	5	histologic	histologic	ADJ
fnp-3025	481	6	analyses	analysis	NOUN
fnp-3025	481	7	in	in	ADP
fnp-3025	481	8	general	general	ADJ
fnp-3025	481	9	,	,	PUNCT
fnp-3025	481	10	as	as	SCONJ
fnp-3025	481	11	methods	method	NOUN
fnp-3025	481	12	and	and	CCONJ
fnp-3025	481	13	interpretations	interpretation	NOUN
fnp-3025	481	14	can	can	AUX
fnp-3025	481	15	vary	vary	VERB
fnp-3025	481	16	among	among	ADP
fnp-3025	481	17	laboratories	laboratory	NOUN
fnp-3025	481	18	(	(	PUNCT
fnp-3025	481	19	e.g.	e.g.	ADV
fnp-3025	481	20	,	,	PUNCT
fnp-3025	481	21	alafuzoff	alafuzoff	NOUN
fnp-3025	481	22	et	et	PROPN
fnp-3025	481	23	al	al	PROPN
fnp-3025	481	24	.	.	PUNCT
fnp-3025	482	1	[	[	X
fnp-3025	482	2	2008	2008	NUM
fnp-3025	482	3	]	]	PUNCT
fnp-3025	483	1	[	[	X
fnp-3025	483	2	reference	reference	NOUN
fnp-3025	483	3	511	511	NUM
fnp-3025	483	4	]	]	PUNCT
fnp-3025	483	5	)	)	PUNCT
fnp-3025	483	6	.	.	PUNCT
fnp-3025	484	1	6.2.3	6.2.3	NUM
fnp-3025	484	2	oligodendrocytes	oligodendrocyte	NOUN
fnp-3025	484	3	compared	compare	VERB
fnp-3025	484	4	to	to	ADP
fnp-3025	484	5	microglia	microglia	ADJ
fnp-3025	484	6	and	and	CCONJ
fnp-3025	484	7	astrocytes	astrocyte	NOUN
fnp-3025	484	8	,	,	PUNCT
fnp-3025	484	9	oligodendrocytes	oligodendrocyte	NOUN
fnp-3025	484	10	have	have	AUX
fnp-3025	484	11	been	be	AUX
fnp-3025	484	12	less	less	ADV
fnp-3025	484	13	studied	study	VERB
fnp-3025	484	14	in	in	ADP
fnp-3025	484	15	ad	ad	NOUN
fnp-3025	484	16	[	[	X
fnp-3025	484	17	358	358	NUM
fnp-3025	484	18	]	]	PUNCT
fnp-3025	484	19	.	.	PUNCT
fnp-3025	485	1	their	their	PRON
fnp-3025	485	2	involvement	involvement	NOUN
fnp-3025	485	3	in	in	ADP
fnp-3025	485	4	plaques	plaque	NOUN
fnp-3025	485	5	has	have	AUX
fnp-3025	485	6	long	long	ADV
fnp-3025	485	7	been	be	AUX
fnp-3025	485	8	debated	debate	VERB
fnp-3025	485	9	(	(	PUNCT
fnp-3025	485	10	see	see	VERB
fnp-3025	485	11	,	,	PUNCT
fnp-3025	485	12	e.g.	e.g.	ADV
fnp-3025	485	13	,	,	PUNCT
fnp-3025	485	14	the	the	DET
fnp-3025	485	15	contrasting	contrast	VERB
fnp-3025	485	16	views	view	NOUN
fnp-3025	485	17	of	of	ADP
fnp-3025	485	18	critchley	critchley	NOUN
fnp-3025	485	19	[	[	X
fnp-3025	485	20	116	116	X
fnp-3025	485	21	]	]	PUNCT
fnp-3025	485	22	and	and	CCONJ
fnp-3025	485	23	ferraro	ferraro	NOUN
fnp-3025	486	1	[	[	X
fnp-3025	486	2	118	118	NUM
fnp-3025	486	3	]	]	NUM
fnp-3025	486	4	:	:	PUNCT
fnp-3025	486	5	‘	'	PUNCT
fnp-3025	486	6	oligodendroglia	oligodendroglia	NOUN
fnp-3025	486	7	apparently	apparently	ADV
fnp-3025	486	8	does	do	AUX
fnp-3025	486	9	not	not	PART
fnp-3025	486	10	participate	participate	VERB
fnp-3025	486	11	in	in	ADP
fnp-3025	486	12	the	the	DET
fnp-3025	486	13	structure	structure	NOUN
fnp-3025	486	14	of	of	ADP
fnp-3025	486	15	plaques	plaque	NOUN
fnp-3025	486	16	’	'	PUNCT
fnp-3025	486	17	[	[	X
fnp-3025	486	18	critchley	critchley	NOUN
fnp-3025	486	19	,	,	PUNCT
fnp-3025	486	20	1929	1929	NUM
fnp-3025	486	21	]	]	PUNCT
fnp-3025	486	22	;	;	PUNCT
fnp-3025	486	23	‘	'	PUNCT
fnp-3025	486	24	it	it	PRON
fnp-3025	486	25	is	be	AUX
fnp-3025	486	26	certain	certain	ADJ
fnp-3025	486	27	,	,	PUNCT
fnp-3025	486	28	then	then	ADV
fnp-3025	486	29	,	,	PUNCT
fnp-3025	486	30	that	that	SCONJ
fnp-3025	486	31	both	both	DET
fnp-3025	486	32	oligodendroglia	oligodendroglia	NOUN
fnp-3025	486	33	and	and	CCONJ
fnp-3025	486	34	microglia	microglia	ADJ
fnp-3025	486	35	cells	cell	NOUN
fnp-3025	486	36	are	be	AUX
fnp-3025	486	37	usual	usual	ADJ
fnp-3025	486	38	components	component	NOUN
fnp-3025	486	39	of	of	ADP
fnp-3025	486	40	senile	senile	ADJ
fnp-3025	486	41	plaques	plaque	NOUN
fnp-3025	486	42	’	'	PUNCT
fnp-3025	487	1	[	[	X
fnp-3025	487	2	ferraro	ferraro	NOUN
fnp-3025	487	3	,	,	PUNCT
fnp-3025	487	4	1931	1931	NUM
fnp-3025	487	5	]	]	PUNCT
fnp-3025	487	6	)	)	PUNCT
fnp-3025	487	7	.	.	PUNCT
fnp-3025	488	1	soniat	soniat	PROPN
fnp-3025	488	2	contended	contend	VERB
fnp-3025	488	3	that	that	SCONJ
fnp-3025	488	4	oligodendrocytes	oligodendrocyte	NOUN
fnp-3025	488	5	are	be	AUX
fnp-3025	488	6	not	not	PART
fnp-3025	488	7	integral	integral	ADJ
fnp-3025	488	8	to	to	ADP
fnp-3025	488	9	the	the	DET
fnp-3025	488	10	formation	formation	NOUN
fnp-3025	488	11	of	of	ADP
fnp-3025	488	12	plaques	plaque	NOUN
fnp-3025	488	13	,	,	PUNCT
fnp-3025	488	14	but	but	CCONJ
fnp-3025	488	15	rather	rather	ADV
fnp-3025	488	16	,	,	PUNCT
fnp-3025	488	17	when	when	SCONJ
fnp-3025	488	18	present	present	ADJ
fnp-3025	488	19	,	,	PUNCT
fnp-3025	488	20	their	their	PRON
fnp-3025	488	21	presence	presence	NOUN
fnp-3025	488	22	is	be	AUX
fnp-3025	488	23	purely	purely	ADV
fnp-3025	488	24	coincidental	coincidental	ADJ
fnp-3025	488	25	[	[	X
fnp-3025	488	26	119	119	NUM
fnp-3025	488	27	]	]	PUNCT
fnp-3025	488	28	.	.	PUNCT
fnp-3025	489	1	a	a	DET
fnp-3025	489	2	recent	recent	ADJ
fnp-3025	489	3	analysis	analysis	NOUN
fnp-3025	489	4	,	,	PUNCT
fnp-3025	489	5	however	however	ADV
fnp-3025	489	6	,	,	PUNCT
fnp-3025	489	7	has	have	AUX
fnp-3025	489	8	revealed	reveal	VERB
fnp-3025	489	9	oligodendrocyte	oligodendrocyte	ADJ
fnp-3025	489	10	progenitor	progenitor	NOUN
fnp-3025	489	11	cells	cell	NOUN
fnp-3025	489	12	in	in	ADP
fnp-3025	489	13	aβ	aβ	ADP
fnp-3025	489	14	plaques	plaque	NOUN
fnp-3025	489	15	that	that	PRON
fnp-3025	489	16	become	become	VERB
fnp-3025	489	17	senescent	senescent	ADJ
fnp-3025	489	18	and	and	CCONJ
fnp-3025	489	19	pro	pro	ADJ
fnp-3025	489	20	-	-	ADJ
fnp-3025	489	21	inflammatory	inflammatory	ADJ
fnp-3025	489	22	,	,	PUNCT
fnp-3025	489	23	in	in	ADP
fnp-3025	489	24	which	which	DET
fnp-3025	489	25	state	state	NOUN
fnp-3025	489	26	they	they	PRON
fnp-3025	489	27	are	be	AUX
fnp-3025	489	28	thought	think	VERB
fnp-3025	489	29	to	to	PART
fnp-3025	489	30	augment	augment	VERB
fnp-3025	489	31	the	the	DET
fnp-3025	489	32	pathogenicity	pathogenicity	NOUN
fnp-3025	489	33	of	of	ADP
fnp-3025	489	34	aberrant	aberrant	NOUN
fnp-3025	489	35	aβ	aβ	NOUN
fnp-3025	490	1	[	[	X
fnp-3025	490	2	359	359	NUM
fnp-3025	490	3	]	]	PUNCT
fnp-3025	490	4	.	.	PUNCT
fnp-3025	491	1	more	more	ADJ
fnp-3025	491	2	work	work	NOUN
fnp-3025	491	3	on	on	ADP
fnp-3025	491	4	oligodendrocytes	oligodendrocyte	NOUN
fnp-3025	491	5	in	in	ADP
fnp-3025	491	6	association	association	NOUN
fnp-3025	491	7	with	with	ADP
fnp-3025	491	8	aβ	aβ	DET
fnp-3025	491	9	plaques	plaque	NOUN
fnp-3025	491	10	is	be	AUX
fnp-3025	491	11	clearly	clearly	ADV
fnp-3025	491	12	needed	need	VERB
fnp-3025	491	13	.	.	PUNCT
fnp-3025	492	1	7	7	X
fnp-3025	492	2	.	.	X
fnp-3025	492	3	the	the	DET
fnp-3025	492	4	broader	broad	ADJ
fnp-3025	492	5	biochemistry	biochemistry	NOUN
fnp-3025	492	6	of	of	ADP
fnp-3025	492	7	aβ	aβ	PRON
fnp-3025	492	8	in	in	ADP
fnp-3025	492	9	plaques	plaque	NOUN
fnp-3025	492	10	the	the	DET
fnp-3025	492	11	number	number	NOUN
fnp-3025	492	12	of	of	ADP
fnp-3025	492	13	molecules	molecule	NOUN
fnp-3025	492	14	that	that	PRON
fnp-3025	492	15	have	have	AUX
fnp-3025	492	16	been	be	AUX
fnp-3025	492	17	linked	link	VERB
fnp-3025	492	18	in	in	ADP
fnp-3025	492	19	some	some	DET
fnp-3025	492	20	way	way	NOUN
fnp-3025	492	21	to	to	ADP
fnp-3025	492	22	aβ	aβ	VERB
fnp-3025	492	23	plaques	plaque	NOUN
fnp-3025	492	24	is	be	AUX
fnp-3025	492	25	considerable	considerable	ADJ
fnp-3025	492	26	(	(	PUNCT
fnp-3025	492	27	see	see	VERB
fnp-3025	492	28	,	,	PUNCT
fnp-3025	492	29	e.g.	e.g.	ADV
fnp-3025	492	30	,	,	PUNCT
fnp-3025	492	31	[	[	X
fnp-3025	492	32	139	139	NUM
fnp-3025	492	33	,	,	PUNCT
fnp-3025	492	34	175	175	NUM
fnp-3025	492	35	,	,	PUNCT
fnp-3025	492	36	278	278	NUM
fnp-3025	492	37	,	,	PUNCT
fnp-3025	492	38	279	279	NUM
fnp-3025	492	39	,	,	PUNCT
fnp-3025	492	40	360	360	NUM
fnp-3025	492	41	-	-	SYM
fnp-3025	492	42	364	364	NUM
fnp-3025	492	43	]	]	PUNCT
fnp-3025	492	44	)	)	PUNCT
fnp-3025	492	45	,	,	PUNCT
fnp-3025	492	46	creating	create	VERB
fnp-3025	492	47	fertile	fertile	ADJ
fnp-3025	492	48	ground	ground	NOUN
fnp-3025	492	49	for	for	ADP
fnp-3025	492	50	hypotheses	hypothesis	NOUN
fnp-3025	492	51	on	on	ADP
fnp-3025	492	52	both	both	CCONJ
fnp-3025	492	53	the	the	DET
fnp-3025	492	54	origin	origin	NOUN
fnp-3025	492	55	of	of	ADP
fnp-3025	492	56	plaques	plaque	NOUN
fnp-3025	492	57	and	and	CCONJ
fnp-3025	492	58	the	the	DET
fnp-3025	492	59	nature	nature	NOUN
fnp-3025	492	60	of	of	ADP
fnp-3025	492	61	ad	ad	NOUN
fnp-3025	492	62	.	.	PUNCT
fnp-3025	493	1	along	along	ADP
fnp-3025	493	2	with	with	ADP
fnp-3025	493	3	the	the	DET
fnp-3025	493	4	many	many	ADJ
fnp-3025	493	5	substances	substance	NOUN
fnp-3025	493	6	directly	directly	ADV
fnp-3025	493	7	associated	associate	VERB
fnp-3025	493	8	with	with	ADP
fnp-3025	493	9	neurons	neuron	NOUN
fnp-3025	493	10	and	and	CCONJ
fnp-3025	493	11	glia	glia	PROPN
fnp-3025	493	12	,	,	PUNCT
fnp-3025	493	13	aggregated	aggregate	VERB
fnp-3025	493	14	aβ	aβ	ADP
fnp-3025	493	15	itself	itself	PRON
fnp-3025	493	16	is	be	AUX
fnp-3025	493	17	rich	rich	ADJ
fnp-3025	493	18	in	in	ADP
fnp-3025	493	19	accompanying	accompany	VERB
fnp-3025	493	20	molecules	molecule	NOUN
fnp-3025	493	21	.	.	PUNCT
fnp-3025	494	1	amyloid	amyloid	NOUN
fnp-3025	494	2	p	p	PROPN
fnp-3025	494	3	component	component	NOUN
fnp-3025	494	4	is	be	AUX
fnp-3025	494	5	present	present	ADJ
fnp-3025	494	6	in	in	ADP
fnp-3025	494	7	different	different	ADJ
fnp-3025	494	8	types	type	NOUN
fnp-3025	494	9	of	of	ADP
fnp-3025	494	10	amyloid	amyloid	NOUN
fnp-3025	494	11	throughout	throughout	ADP
fnp-3025	494	12	the	the	DET
fnp-3025	494	13	body	body	NOUN
fnp-3025	494	14	[	[	X
fnp-3025	494	15	6	6	NUM
fnp-3025	494	16	,	,	PUNCT
fnp-3025	494	17	365	365	NUM
fnp-3025	494	18	]	]	PUNCT
fnp-3025	494	19	,	,	PUNCT
fnp-3025	494	20	including	include	VERB
fnp-3025	494	21	aβ	aβ	ADP
fnp-3025	494	22	plaques	plaque	NOUN
fnp-3025	494	23	[	[	X
fnp-3025	494	24	364	364	NUM
fnp-3025	494	25	,	,	PUNCT
fnp-3025	494	26	366	366	NUM
fnp-3025	494	27	,	,	PUNCT
fnp-3025	494	28	367	367	NUM
fnp-3025	494	29	]	]	PUNCT
fnp-3025	494	30	.	.	PUNCT
fnp-3025	495	1	other	other	ADJ
fnp-3025	495	2	molecules	molecule	NOUN
fnp-3025	495	3	that	that	PRON
fnp-3025	495	4	have	have	AUX
fnp-3025	495	5	been	be	AUX
fnp-3025	495	6	reported	report	VERB
fnp-3025	495	7	to	to	PART
fnp-3025	495	8	directly	directly	ADV
fnp-3025	495	9	co	co	VERB
fnp-3025	495	10	-	-	VERB
fnp-3025	495	11	localize	localize	VERB
fnp-3025	495	12	with	with	ADP
fnp-3025	495	13	at	at	ADP
fnp-3025	495	14	least	least	ADJ
fnp-3025	495	15	some	some	PRON
fnp-3025	495	16	aβ	aβ	NOUN
fnp-3025	495	17	deposits	deposit	NOUN
fnp-3025	495	18	include	include	VERB
fnp-3025	495	19	proteoglycans	proteoglycan	NOUN
fnp-3025	495	20	[	[	X
fnp-3025	495	21	6	6	NUM
fnp-3025	495	22	,	,	PUNCT
fnp-3025	495	23	364	364	NUM
fnp-3025	495	24	,	,	PUNCT
fnp-3025	495	25	368	368	NUM
fnp-3025	495	26	,	,	PUNCT
fnp-3025	495	27	369	369	NUM
fnp-3025	495	28	]	]	PUNCT
fnp-3025	495	29	,	,	PUNCT
fnp-3025	495	30	complement	complement	NOUN
fnp-3025	495	31	proteins	protein	NOUN
fnp-3025	495	32	[	[	X
fnp-3025	495	33	370	370	NUM
fnp-3025	495	34	-	-	SYM
fnp-3025	495	35	373	373	NUM
fnp-3025	495	36	]	]	PUNCT
fnp-3025	495	37	,	,	PUNCT
fnp-3025	495	38	apolipoprotein	apolipoprotein	ADJ
fnp-3025	495	39	e	e	PROPN
fnp-3025	496	1	[	[	X
fnp-3025	496	2	374	374	NUM
fnp-3025	496	3	,	,	PUNCT
fnp-3025	496	4	375	375	NUM
fnp-3025	496	5	]	]	PUNCT
fnp-3025	496	6	,	,	PUNCT
fnp-3025	496	7	alpha-1	alpha-1	PRON
fnp-3025	496	8	antichymotrypsin	antichymotrypsin	VERB
fnp-3025	496	9	[	[	X
fnp-3025	496	10	376	376	NUM
fnp-3025	496	11	]	]	PUNCT
fnp-3025	496	12	and	and	CCONJ
fnp-3025	496	13	advanced	advanced	ADJ
fnp-3025	496	14	glycation	glycation	NOUN
fnp-3025	496	15	end	end	NOUN
fnp-3025	496	16	products	product	NOUN
fnp-3025	496	17	[	[	X
fnp-3025	496	18	377	377	NUM
fnp-3025	496	19	,	,	PUNCT
fnp-3025	496	20	378	378	NUM
fnp-3025	496	21	]	]	PUNCT
fnp-3025	496	22	,	,	PUNCT
fnp-3025	496	23	along	along	ADP
fnp-3025	496	24	with	with	ADP
fnp-3025	496	25	lipids	lipid	NOUN
fnp-3025	496	26	,	,	PUNCT
fnp-3025	496	27	metal	metal	NOUN
fnp-3025	496	28	ions	ion	NOUN
fnp-3025	496	29	,	,	PUNCT
fnp-3025	496	30	reactive	reactive	ADJ
fnp-3025	496	31	oxygen	oxygen	NOUN
fnp-3025	496	32	species	specie	NOUN
fnp-3025	496	33	and	and	CCONJ
fnp-3025	496	34	nucleic	nucleic	ADJ
fnp-3025	496	35	acids	acid	NOUN
fnp-3025	496	36	(	(	PUNCT
fnp-3025	496	37	see	see	VERB
fnp-3025	496	38	stewart	stewart	PROPN
fnp-3025	496	39	and	and	CCONJ
fnp-3025	496	40	radford	radford	PROPN
fnp-3025	497	1	[	[	X
fnp-3025	497	2	364	364	NUM
fnp-3025	497	3	]	]	PUNCT
fnp-3025	497	4	)	)	PUNCT
fnp-3025	497	5	.	.	PUNCT
fnp-3025	498	1	how	how	SCONJ
fnp-3025	498	2	aβ	aβ	NOUN
fnp-3025	498	3	-	-	PUNCT
fnp-3025	498	4	linked	link	VERB
fnp-3025	498	5	substances	substance	NOUN
fnp-3025	498	6	might	might	AUX
fnp-3025	498	7	be	be	AUX
fnp-3025	498	8	involved	involve	VERB
fnp-3025	498	9	in	in	ADP
fnp-3025	498	10	the	the	DET
fnp-3025	498	11	pathobiology	pathobiology	NOUN
fnp-3025	498	12	of	of	ADP
fnp-3025	498	13	plaques	plaque	NOUN
fnp-3025	498	14	is	be	AUX
fnp-3025	498	15	attracting	attract	VERB
fnp-3025	498	16	increasing	increase	VERB
fnp-3025	498	17	attention	attention	NOUN
fnp-3025	498	18	.	.	PUNCT
fnp-3025	499	1	for	for	ADP
fnp-3025	499	2	instance	instance	NOUN
fnp-3025	499	3	,	,	PUNCT
fnp-3025	499	4	a	a	DET
fnp-3025	499	5	study	study	NOUN
fnp-3025	499	6	in	in	ADP
fnp-3025	499	7	mice	mouse	NOUN
fnp-3025	499	8	found	find	VERB
fnp-3025	499	9	that	that	SCONJ
fnp-3025	499	10	aβ	aβ	PRON
fnp-3025	499	11	bound	bind	VERB
fnp-3025	499	12	to	to	ADP
fnp-3025	499	13	nucleic	nucleic	ADJ
fnp-3025	499	14	acids	acid	NOUN
fnp-3025	499	15	acts	act	NOUN
fnp-3025	499	16	as	as	ADP
fnp-3025	499	17	an	an	DET
fnp-3025	499	18	immune	immune	ADJ
fnp-3025	499	19	signal	signal	NOUN
fnp-3025	499	20	,	,	PUNCT
fnp-3025	499	21	stimulating	stimulate	VERB
fnp-3025	499	22	an	an	DET
fnp-3025	499	23	antiviral	antiviral	ADJ
fnp-3025	499	24	response	response	NOUN
fnp-3025	499	25	in	in	ADP
fnp-3025	499	26	microglia	microglia	NOUN
fnp-3025	499	27	and	and	CCONJ
fnp-3025	499	28	astrocytes	astrocyte	NOUN
fnp-3025	499	29	that	that	PRON
fnp-3025	499	30	instigates	instigate	VERB
fnp-3025	499	31	the	the	DET
fnp-3025	499	32	complement	complement	NOUN
fnp-3025	499	33	-	-	PUNCT
fnp-3025	499	34	mediated	mediate	VERB
fnp-3025	499	35	elimination	elimination	NOUN
fnp-3025	499	36	of	of	ADP
fnp-3025	499	37	local	local	ADJ
fnp-3025	499	38	synapses	synapsis	NOUN
fnp-3025	499	39	[	[	X
fnp-3025	499	40	379	379	NUM
fnp-3025	499	41	]	]	PUNCT
fnp-3025	499	42	.	.	PUNCT
fnp-3025	500	1	the	the	DET
fnp-3025	500	2	plaque	plaque	NOUN
fnp-3025	500	3	-	-	PUNCT
fnp-3025	500	4	associated	associate	VERB
fnp-3025	500	5	proteome	proteome	NOUN
fnp-3025	500	6	can	can	AUX
fnp-3025	500	7	be	be	AUX
fnp-3025	500	8	interrogated	interrogate	VERB
fnp-3025	500	9	by	by	ADP
fnp-3025	500	10	laser	laser	NOUN
fnp-3025	500	11	-	-	PUNCT
fnp-3025	500	12	microdissection	microdissection	NOUN
fnp-3025	500	13	of	of	ADP
fnp-3025	500	14	aβ	aβ	PRON
fnp-3025	500	15	plaques	plaque	NOUN
fnp-3025	500	16	followed	follow	VERB
fnp-3025	500	17	by	by	ADP
fnp-3025	500	18	mass	mass	ADJ
fnp-3025	500	19	-	-	PUNCT
fnp-3025	500	20	spectrometric	spectrometric	ADJ
fnp-3025	500	21	analysis	analysis	NOUN
fnp-3025	500	22	[	[	X
fnp-3025	500	23	380	380	NUM
fnp-3025	500	24	-	-	SYM
fnp-3025	500	25	385	385	NUM
fnp-3025	500	26	]	]	PUNCT
fnp-3025	500	27	.	.	PUNCT
fnp-3025	501	1	these	these	DET
fnp-3025	501	2	studies	study	NOUN
fnp-3025	501	3	have	have	AUX
fnp-3025	501	4	identified	identify	VERB
fnp-3025	501	5	numerous	numerous	ADJ
fnp-3025	501	6	proteins	protein	NOUN
fnp-3025	501	7	that	that	PRON
fnp-3025	501	8	are	be	AUX
fnp-3025	501	9	enriched	enrich	VERB
fnp-3025	501	10	in	in	ADP
fnp-3025	501	11	plaques	plaque	NOUN
fnp-3025	501	12	,	,	PUNCT
fnp-3025	501	13	though	though	SCONJ
fnp-3025	501	14	whether	whether	SCONJ
fnp-3025	501	15	they	they	PRON
fnp-3025	501	16	are	be	AUX
fnp-3025	501	17	directly	directly	ADV
fnp-3025	501	18	associated	associate	VERB
fnp-3025	501	19	with	with	ADP
fnp-3025	501	20	multimeric	multimeric	ADJ
fnp-3025	501	21	aβ	aβ	NOUN
fnp-3025	501	22	or	or	CCONJ
fnp-3025	501	23	with	with	ADP
fnp-3025	501	24	the	the	DET
fnp-3025	501	25	cellular	cellular	ADJ
fnp-3025	501	26	constituents	constituent	NOUN
fnp-3025	501	27	is	be	AUX
fnp-3025	501	28	sometimes	sometimes	ADV
fnp-3025	501	29	undefined	undefined	ADJ
fnp-3025	501	30	.	.	PUNCT
fnp-3025	502	1	it	it	PRON
fnp-3025	502	2	has	have	AUX
fnp-3025	502	3	been	be	AUX
fnp-3025	502	4	proposed	propose	VERB
fnp-3025	502	5	that	that	SCONJ
fnp-3025	502	6	plaques	plaque	NOUN
fnp-3025	502	7	mature	mature	VERB
fnp-3025	502	8	through	through	ADP
fnp-3025	502	9	three	three	NUM
fnp-3025	502	10	biochemical	biochemical	ADJ
fnp-3025	502	11	stages	stage	NOUN
fnp-3025	502	12	within	within	ADP
fnp-3025	502	13	which	which	PRON
fnp-3025	502	14	the	the	DET
fnp-3025	502	15	toxicity	toxicity	NOUN
fnp-3025	502	16	of	of	ADP
fnp-3025	502	17	the	the	DET
fnp-3025	502	18	aggregates	aggregate	NOUN
fnp-3025	502	19	may	may	AUX
fnp-3025	502	20	differ	differ	VERB
fnp-3025	502	21	;	;	PUNCT
fnp-3025	502	22	in	in	ADP
fnp-3025	502	23	stage	stage	NOUN
fnp-3025	502	24	1	1	NUM
fnp-3025	502	25	,	,	PUNCT
fnp-3025	502	26	the	the	DET
fnp-3025	502	27	aggregates	aggregate	NOUN
fnp-3025	502	28	lack	lack	VERB
fnp-3025	502	29	both	both	DET
fnp-3025	502	30	pyroglutamation	pyroglutamation	NOUN
fnp-3025	502	31	at	at	ADP
fnp-3025	502	32	residue	residue	NOUN
fnp-3025	502	33	3	3	NUM
fnp-3025	502	34	(	(	PUNCT
fnp-3025	502	35	aβnp3e	aβnp3e	NOUN
fnp-3025	502	36	)	)	PUNCT
fnp-3025	502	37	and	and	CCONJ
fnp-3025	502	38	phosphorylation	phosphorylation	NOUN
fnp-3025	502	39	at	at	ADP
fnp-3025	502	40	residue	residue	NOUN
fnp-3025	502	41	8	8	NUM
fnp-3025	502	42	(	(	PUNCT
fnp-3025	502	43	pser8aβ	pser8aβ	NOUN
fnp-3025	502	44	)	)	PUNCT
fnp-3025	502	45	;	;	PUNCT
fnp-3025	502	46	in	in	ADP
fnp-3025	502	47	stage	stage	NOUN
fnp-3025	502	48	2	2	NUM
fnp-3025	502	49	,	,	PUNCT
fnp-3025	502	50	aβnp3e	aβnp3e	PRON
fnp-3025	502	51	appears	appear	VERB
fnp-3025	502	52	,	,	PUNCT
fnp-3025	502	53	and	and	CCONJ
fnp-3025	502	54	in	in	ADP
fnp-3025	502	55	stage	stage	NOUN
fnp-3025	502	56	3	3	NUM
fnp-3025	502	57	,	,	PUNCT
fnp-3025	502	58	both	both	PRON
fnp-3025	502	59	aβnp3e	aβnp3e	NOUN
fnp-3025	502	60	and	and	CCONJ
fnp-3025	502	61	pser8aβ	pser8aβ	NOUN
fnp-3025	502	62	are	be	AUX
fnp-3025	502	63	present	present	ADJ
fnp-3025	502	64	[	[	X
fnp-3025	502	65	19	19	NUM
fnp-3025	502	66	,	,	PUNCT
fnp-3025	502	67	386	386	NUM
fnp-3025	502	68	]	]	PUNCT
fnp-3025	502	69	.	.	PUNCT
fnp-3025	503	1	post	post	ADJ
fnp-3025	503	2	-	-	ADJ
fnp-3025	503	3	translational	translational	ADJ
fnp-3025	503	4	chemical	chemical	NOUN
fnp-3025	503	5	modifications	modification	NOUN
fnp-3025	503	6	of	of	ADP
fnp-3025	503	7	aβ	aβ	PRON
fnp-3025	503	8	can	can	AUX
fnp-3025	503	9	influence	influence	VERB
fnp-3025	503	10	the	the	DET
fnp-3025	503	11	aggregation	aggregation	NOUN
fnp-3025	503	12	of	of	ADP
fnp-3025	503	13	the	the	DET
fnp-3025	503	14	protein	protein	NOUN
fnp-3025	503	15	along	along	ADP
fnp-3025	503	16	with	with	ADP
fnp-3025	503	17	the	the	DET
fnp-3025	503	18	type	type	NOUN
fnp-3025	503	19	of	of	ADP
fnp-3025	503	20	deposit	deposit	NOUN
fnp-3025	503	21	that	that	PRON
fnp-3025	503	22	is	be	AUX
fnp-3025	503	23	formed	form	VERB
fnp-3025	503	24	in	in	ADP
fnp-3025	503	25	the	the	DET
fnp-3025	503	26	brain	brain	NOUN
fnp-3025	503	27	[	[	X
fnp-3025	503	28	19	19	NUM
fnp-3025	503	29	,	,	PUNCT
fnp-3025	503	30	387	387	NUM
fnp-3025	503	31	-	-	SYM
fnp-3025	503	32	391	391	NUM
fnp-3025	503	33	]	]	PUNCT
fnp-3025	503	34	,	,	PUNCT
fnp-3025	503	35	but	but	CCONJ
fnp-3025	503	36	the	the	DET
fnp-3025	503	37	mechanisms	mechanism	NOUN
fnp-3025	503	38	are	be	AUX
fnp-3025	503	39	,	,	PUNCT
fnp-3025	503	40	in	in	ADP
fnp-3025	503	41	many	many	ADJ
fnp-3025	503	42	cases	case	NOUN
fnp-3025	503	43	,	,	PUNCT
fnp-3025	503	44	still	still	ADV
fnp-3025	503	45	uncertain	uncertain	ADJ
fnp-3025	503	46	.	.	PUNCT
fnp-3025	504	1	8	8	X
fnp-3025	504	2	.	.	X
fnp-3025	504	3	microbes	microbe	NOUN
fnp-3025	504	4	and	and	CCONJ
fnp-3025	504	5	plaques	plaque	VERB
fnp-3025	504	6	the	the	DET
fnp-3025	504	7	notion	notion	NOUN
fnp-3025	504	8	that	that	SCONJ
fnp-3025	504	9	microbes	microbe	NOUN
fnp-3025	504	10	might	might	AUX
fnp-3025	504	11	participate	participate	VERB
fnp-3025	504	12	in	in	ADP
fnp-3025	504	13	the	the	DET
fnp-3025	504	14	genesis	genesis	NOUN
fnp-3025	504	15	of	of	ADP
fnp-3025	504	16	plaques	plaque	NOUN
fnp-3025	504	17	has	have	AUX
fnp-3025	504	18	been	be	AUX
fnp-3025	504	19	considered	consider	VERB
fnp-3025	504	20	at	at	ADP
fnp-3025	504	21	least	least	ADJ
fnp-3025	504	22	since	since	SCONJ
fnp-3025	504	23	the	the	DET
fnp-3025	504	24	early	early	ADJ
fnp-3025	504	25	20th	20th	ADJ
fnp-3025	504	26	century.14	century.14	NOUN
fnp-3025	504	27	fischer	fischer	PROPN
fnp-3025	504	28	likened	liken	VERB
fnp-3025	504	29	mature	mature	ADJ
fnp-3025	504	30	plaques	plaque	NOUN
fnp-3025	504	31	to	to	ADP
fnp-3025	504	32	actinomyces	actinomyce	NOUN
fnp-3025	504	33	‘	'	PUNCT
fnp-3025	504	34	drusen	drusen	PROPN
fnp-3025	504	35	’	'	PUNCT
fnp-3025	504	36	,	,	PUNCT
fnp-3025	504	37	although	although	SCONJ
fnp-3025	504	38	he	he	PRON
fnp-3025	504	39	noted	note	VERB
fnp-3025	504	40	that	that	SCONJ
fnp-3025	504	41	they	they	PRON
fnp-3025	504	42	were	be	AUX
fnp-3025	504	43	negative	negative	ADJ
fnp-3025	504	44	for	for	ADP
fnp-3025	504	45	multiple	multiple	ADJ
fnp-3025	504	46	bacterial	bacterial	ADJ
fnp-3025	504	47	stains	stain	NOUN
fnp-3025	504	48	[	[	X
fnp-3025	504	49	117	117	NUM
fnp-3025	504	50	]	]	PUNCT
fnp-3025	504	51	.	.	PUNCT
fnp-3025	505	1	critchley	critchley	PROPN
fnp-3025	505	2	remarked	remark	VERB
fnp-3025	505	3	in	in	ADP
fnp-3025	505	4	1929	1929	NUM
fnp-3025	505	5	that	that	SCONJ
fnp-3025	505	6	the	the	DET
fnp-3025	505	7	microbial	microbial	ADJ
fnp-3025	505	8	origin	origin	NOUN
fnp-3025	505	9	hypothesis	hypothesis	NOUN
fnp-3025	505	10	had	have	AUX
fnp-3025	505	11	failed	fail	VERB
fnp-3025	505	12	to	to	PART
fnp-3025	505	13	gain	gain	VERB
fnp-3025	505	14	traction	traction	NOUN
fnp-3025	506	1	[	[	X
fnp-3025	506	2	116	116	NUM
fnp-3025	506	3	]	]	PUNCT
fnp-3025	506	4	.	.	PUNCT
fnp-3025	507	1	despite	despite	SCONJ
fnp-3025	507	2	more	more	ADV
fnp-3025	507	3	recent	recent	ADJ
fnp-3025	507	4	claims	claim	NOUN
fnp-3025	507	5	that	that	SCONJ
fnp-3025	507	6	senile	senile	ADJ
fnp-3025	507	7	plaques	plaque	NOUN
fnp-3025	507	8	in	in	ADP
fnp-3025	507	9	ad	ad	NOUN
fnp-3025	507	10	‘	'	PUNCT
fnp-3025	507	11	are	be	AUX
fnp-3025	507	12	made	make	VERB
fnp-3025	507	13	up	up	ADP
fnp-3025	507	14	by	by	ADP
fnp-3025	507	15	spirochetes	spirochete	NOUN
fnp-3025	507	16	’	'	PUNCT
fnp-3025	508	1	[	[	X
fnp-3025	508	2	392	392	NUM
fnp-3025	508	3	]	]	PUNCT
fnp-3025	508	4	,	,	PUNCT
fnp-3025	508	5	there	there	PRON
fnp-3025	508	6	is	be	VERB
fnp-3025	508	7	still	still	ADV
fnp-3025	508	8	no	no	DET
fnp-3025	508	9	credible	credible	ADJ
fnp-3025	508	10	evidence	evidence	NOUN
fnp-3025	508	11	that	that	SCONJ
fnp-3025	508	12	aβ	aβ	DET
fnp-3025	508	13	plaques	plaque	NOUN
fnp-3025	508	14	are	be	AUX
fnp-3025	508	15	primarily	primarily	ADV
fnp-3025	508	16	collections	collection	NOUN
fnp-3025	508	17	of	of	ADP
fnp-3025	508	18	microbes	microbe	NOUN
fnp-3025	508	19	or	or	CCONJ
fnp-3025	508	20	their	their	PRON
fnp-3025	508	21	remains	remain	NOUN
fnp-3025	508	22	.	.	PUNCT
fnp-3025	509	1	that	that	PRON
fnp-3025	509	2	said	say	VERB
fnp-3025	509	3	,	,	PUNCT
fnp-3025	509	4	there	there	PRON
fnp-3025	509	5	is	be	VERB
fnp-3025	509	6	fairly	fairly	ADV
fnp-3025	509	7	compelling	compelling	ADJ
fnp-3025	509	8	evidence	evidence	NOUN
fnp-3025	509	9	that	that	SCONJ
fnp-3025	509	10	certain	certain	ADJ
fnp-3025	509	11	microbial	microbial	ADJ
fnp-3025	509	12	infections	infection	NOUN
fnp-3025	509	13	are	be	AUX
fnp-3025	509	14	risk	risk	NOUN
fnp-3025	509	15	factors	factor	NOUN
fnp-3025	509	16	for	for	ADP
fnp-3025	509	17	ad	ad	NOUN
fnp-3025	509	18	[	[	X
fnp-3025	509	19	393	393	NUM
fnp-3025	509	20	-	-	SYM
fnp-3025	509	21	395	395	NUM
fnp-3025	509	22	]	]	PUNCT
fnp-3025	509	23	.	.	PUNCT
fnp-3025	510	1	perhaps	perhaps	ADV
fnp-3025	510	2	the	the	DET
fnp-3025	510	3	best	good	ADJ
fnp-3025	510	4	evidence	evidence	NOUN
fnp-3025	510	5	indicates	indicate	VERB
fnp-3025	510	6	that	that	SCONJ
fnp-3025	510	7	some	some	DET
fnp-3025	510	8	herpesviridae	herpesviridae	NOUN
fnp-3025	510	9	increase	increase	VERB
fnp-3025	510	10	the	the	DET
fnp-3025	510	11	probability	probability	NOUN
fnp-3025	510	12	of	of	ADP
fnp-3025	510	13	developing	develop	VERB
fnp-3025	510	14	ad	ad	NOUN
fnp-3025	510	15	[	[	X
fnp-3025	510	16	394	394	NUM
fnp-3025	510	17	,	,	PUNCT
fnp-3025	510	18	396	396	NUM
fnp-3025	510	19	,	,	PUNCT
fnp-3025	510	20	397	397	NUM
fnp-3025	510	21	]	]	PUNCT
fnp-3025	510	22	.	.	PUNCT
fnp-3025	511	1	over	over	ADP
fnp-3025	511	2	15	15	NUM
fnp-3025	511	3	different	different	ADJ
fnp-3025	511	4	microbes	microbe	NOUN
fnp-3025	511	5	have	have	AUX
fnp-3025	511	6	been	be	AUX
fnp-3025	511	7	linked	link	VERB
fnp-3025	511	8	to	to	ADP
fnp-3025	511	9	ad	ad	NOUN
fnp-3025	511	10	by	by	ADP
fnp-3025	511	11	various	various	ADJ
fnp-3025	511	12	researchers	researcher	NOUN
fnp-3025	511	13	[	[	X
fnp-3025	511	14	398	398	NUM
fnp-3025	511	15	]	]	PUNCT
fnp-3025	511	16	,	,	PUNCT
fnp-3025	511	17	but	but	CCONJ
fnp-3025	511	18	in	in	ADP
fnp-3025	511	19	many	many	ADJ
fnp-3025	511	20	instances	instance	NOUN
fnp-3025	511	21	the	the	DET
fnp-3025	511	22	findings	finding	NOUN
fnp-3025	511	23	are	be	AUX
fnp-3025	511	24	weak	weak	ADJ
fnp-3025	511	25	or	or	CCONJ
fnp-3025	511	26	contradictory	contradictory	ADJ
fnp-3025	511	27	(	(	PUNCT
fnp-3025	511	28	see	see	ADJ
fnp-3025	511	29	,	,	PUNCT
fnp-3025	511	30	e.g.	e.g.	ADV
fnp-3025	511	31	,	,	PUNCT
fnp-3025	511	32	[	[	X
fnp-3025	511	33	399	399	NUM
fnp-3025	511	34	,	,	PUNCT
fnp-3025	511	35	400	400	NUM
fnp-3025	511	36	]	]	PUNCT
fnp-3025	511	37	)	)	PUNCT
fnp-3025	511	38	.	.	PUNCT
fnp-3025	512	1	in	in	ADP
fnp-3025	512	2	addition	addition	NOUN
fnp-3025	512	3	,	,	PUNCT
fnp-3025	512	4	it	it	PRON
fnp-3025	512	5	is	be	AUX
fnp-3025	512	6	important	important	ADJ
fnp-3025	512	7	to	to	PART
fnp-3025	512	8	distinguish	distinguish	VERB
fnp-3025	512	9	cases	case	NOUN
fnp-3025	512	10	of	of	ADP
fnp-3025	512	11	dementia	dementia	NOUN
fnp-3025	512	12	in	in	ADP
fnp-3025	512	13	general	general	ADJ
fnp-3025	512	14	(	(	PUNCT
fnp-3025	512	15	for	for	ADP
fnp-3025	512	16	which	which	PRON
fnp-3025	512	17	there	there	PRON
fnp-3025	512	18	are	be	VERB
fnp-3025	512	19	over	over	ADP
fnp-3025	512	20	50	50	NUM
fnp-3025	512	21	different	different	ADJ
fnp-3025	512	22	causes	cause	NOUN
fnp-3025	512	23	[	[	X
fnp-3025	512	24	330	330	NUM
fnp-3025	512	25	]	]	PUNCT
fnp-3025	512	26	)	)	PUNCT
fnp-3025	512	27	from	from	ADP
fnp-3025	512	28	cases	case	NOUN
fnp-3025	512	29	of	of	ADP
fnp-3025	512	30	dementia	dementia	NOUN
fnp-3025	512	31	specifically	specifically	ADV
fnp-3025	512	32	due	due	ADP
fnp-3025	512	33	to	to	ADP
fnp-3025	512	34	the	the	DET
fnp-3025	512	35	pathology	pathology	NOUN
fnp-3025	512	36	of	of	ADP
fnp-3025	512	37	ad	ad	NOUN
fnp-3025	512	38	(	(	PUNCT
fnp-3025	512	39	as	as	SCONJ
fnp-3025	512	40	defined	define	VERB
fnp-3025	512	41	by	by	ADP
fnp-3025	512	42	jack	jack	NOUN
fnp-3025	512	43	and	and	CCONJ
fnp-3025	512	44	colleagues	colleague	NOUN
fnp-3025	512	45	[	[	X
fnp-3025	512	46	109	109	NUM
fnp-3025	512	47	]	]	PUNCT
fnp-3025	512	48	)	)	PUNCT
fnp-3025	512	49	.	.	PUNCT
fnp-3025	513	1	it	it	PRON
fnp-3025	513	2	is	be	AUX
fnp-3025	513	3	fair	fair	ADJ
fnp-3025	513	4	to	to	PART
fnp-3025	513	5	say	say	VERB
fnp-3025	513	6	that	that	SCONJ
fnp-3025	513	7	no	no	DET
fnp-3025	513	8	known	know	VERB
fnp-3025	513	9	infectious	infectious	ADJ
fnp-3025	513	10	agent	agent	NOUN
fnp-3025	513	11	is	be	AUX
fnp-3025	513	12	universally	universally	ADV
fnp-3025	513	13	and	and	CCONJ
fnp-3025	513	14	exclusively	exclusively	ADV
fnp-3025	513	15	associated	associate	VERB
fnp-3025	513	16	with	with	ADP
fnp-3025	513	17	ad	ad	NOUN
fnp-3025	513	18	[	[	X
fnp-3025	513	19	395	395	NUM
fnp-3025	513	20	]	]	PUNCT
fnp-3025	513	21	,	,	PUNCT
fnp-3025	513	22	but	but	CCONJ
fnp-3025	513	23	it	it	PRON
fnp-3025	513	24	seems	seem	VERB
fnp-3025	513	25	likely	likely	ADJ
fnp-3025	513	26	that	that	SCONJ
fnp-3025	513	27	any	any	PRON
fnp-3025	513	28	of	of	ADP
fnp-3025	513	29	several	several	ADJ
fnp-3025	513	30	types	type	NOUN
fnp-3025	513	31	of	of	ADP
fnp-3025	513	32	brain	brain	NOUN
fnp-3025	513	33	infection	infection	NOUN
fnp-3025	513	34	(	(	PUNCT
fnp-3025	513	35	including	include	VERB
fnp-3025	513	36	chronic	chronic	ADJ
fnp-3025	513	37	infection	infection	NOUN
fnp-3025	513	38	and/or	and/or	CCONJ
fnp-3025	513	39	reactivation	reactivation	NOUN
fnp-3025	513	40	of	of	ADP
fnp-3025	513	41	resident	resident	ADJ
fnp-3025	513	42	microbes	microbe	NOUN
fnp-3025	513	43	)	)	PUNCT
fnp-3025	513	44	can	can	AUX
fnp-3025	513	45	accelerate	accelerate	VERB
fnp-3025	513	46	plaque	plaque	NOUN
fnp-3025	513	47	formation	formation	NOUN
fnp-3025	513	48	and	and	CCONJ
fnp-3025	513	49	the	the	DET
fnp-3025	513	50	pathogenesis	pathogenesis	NOUN
fnp-3025	513	51	of	of	ADP
fnp-3025	513	52	ad	ad	NOUN
fnp-3025	513	53	[	[	X
fnp-3025	513	54	394	394	NUM
fnp-3025	513	55	,	,	PUNCT
fnp-3025	513	56	395	395	NUM
fnp-3025	513	57	,	,	PUNCT
fnp-3025	513	58	401	401	NUM
fnp-3025	513	59	,	,	PUNCT
fnp-3025	513	60	402	402	NUM
fnp-3025	513	61	]	]	PUNCT
fnp-3025	513	62	.	.	PUNCT
fnp-3025	514	1	in	in	ADP
fnp-3025	514	2	other	other	ADJ
fnp-3025	514	3	words	word	NOUN
fnp-3025	514	4	,	,	PUNCT
fnp-3025	514	5	at	at	ADP
fnp-3025	514	6	least	least	ADJ
fnp-3025	514	7	in	in	ADP
fnp-3025	514	8	some	some	DET
fnp-3025	514	9	instances	instance	NOUN
fnp-3025	514	10	the	the	DET
fnp-3025	514	11	development	development	NOUN
fnp-3025	514	12	of	of	ADP
fnp-3025	514	13	plaques	plaque	NOUN
fnp-3025	514	14	may	may	AUX
fnp-3025	514	15	represent	represent	VERB
fnp-3025	514	16	a	a	DET
fnp-3025	514	17	non	non	ADJ
fnp-3025	514	18	-	-	ADJ
fnp-3025	514	19	specific	specific	ADJ
fnp-3025	514	20	response	response	NOUN
fnp-3025	514	21	to	to	ADP
fnp-3025	514	22	various	various	ADJ
fnp-3025	514	23	infectious	infectious	ADJ
fnp-3025	514	24	organisms	organism	NOUN
fnp-3025	514	25	.	.	PUNCT
fnp-3025	515	1	aggregated	aggregate	VERB
fnp-3025	515	2	aβ	aβ	ADP
fnp-3025	515	3	has	have	VERB
fnp-3025	515	4	antimicrobial	antimicrobial	ADJ
fnp-3025	515	5	properties	property	NOUN
fnp-3025	515	6	[	[	X
fnp-3025	515	7	395	395	NUM
fnp-3025	515	8	,	,	PUNCT
fnp-3025	515	9	403	403	NUM
fnp-3025	515	10	,	,	PUNCT
fnp-3025	515	11	404	404	NUM
fnp-3025	515	12	]	]	PUNCT
fnp-3025	515	13	,	,	PUNCT
fnp-3025	515	14	and	and	CCONJ
fnp-3025	515	15	some	some	DET
fnp-3025	515	16	microbial	microbial	ADJ
fnp-3025	515	17	antigens	antigen	NOUN
fnp-3025	515	18	have	have	AUX
fnp-3025	515	19	been	be	AUX
fnp-3025	515	20	reported	report	VERB
fnp-3025	515	21	in	in	ADP
fnp-3025	515	22	aβ	aβ	ADP
fnp-3025	515	23	plaques	plaque	NOUN
fnp-3025	516	1	[	[	X
fnp-3025	516	2	392	392	NUM
fnp-3025	516	3	,	,	PUNCT
fnp-3025	516	4	405	405	NUM
fnp-3025	516	5	]	]	PUNCT
fnp-3025	516	6	,	,	PUNCT
fnp-3025	516	7	but	but	CCONJ
fnp-3025	516	8	a	a	DET
fnp-3025	516	9	systematic	systematic	ADJ
fnp-3025	516	10	and	and	CCONJ
fnp-3025	516	11	comprehensive	comprehensive	ADJ
fnp-3025	516	12	survey	survey	NOUN
fnp-3025	516	13	of	of	ADP
fnp-3025	516	14	microbial	microbial	ADJ
fnp-3025	516	15	markers	marker	NOUN
fnp-3025	516	16	in	in	ADP
fnp-3025	516	17	different	different	ADJ
fnp-3025	516	18	types	type	NOUN
fnp-3025	516	19	of	of	ADP
fnp-3025	516	20	plaques	plaque	NOUN
fnp-3025	516	21	and	and	CCONJ
fnp-3025	516	22	aβ	aβ	NOUN
fnp-3025	516	23	-	-	PUNCT
fnp-3025	516	24	caa	caa	NOUN
fnp-3025	516	25	throughout	throughout	ADP
fnp-3025	516	26	the	the	DET
fnp-3025	516	27	central	central	ADJ
fnp-3025	516	28	nervous	nervous	ADJ
fnp-3025	516	29	system	system	NOUN
fnp-3025	516	30	has	have	AUX
fnp-3025	516	31	not	not	PART
fnp-3025	516	32	been	be	AUX
fnp-3025	516	33	reported	report	VERB
fnp-3025	516	34	.	.	PUNCT
fnp-3025	517	1	app	app	ADJ
fnp-3025	517	2	-	-	PUNCT
fnp-3025	517	3	transgenic	transgenic	NOUN
fnp-3025	517	4	mice	mouse	NOUN
fnp-3025	517	5	raised	raise	VERB
fnp-3025	517	6	in	in	ADP
fnp-3025	517	7	a	a	DET
fnp-3025	517	8	germ	germ	NOUN
fnp-3025	517	9	-	-	PUNCT
fnp-3025	517	10	free	free	ADJ
fnp-3025	517	11	environment	environment	NOUN
fnp-3025	517	12	develop	develop	VERB
fnp-3025	517	13	some	some	PRON
fnp-3025	517	14	aβ	aβ	NOUN
fnp-3025	517	15	plaques	plaque	NOUN
fnp-3025	517	16	as	as	SCONJ
fnp-3025	517	17	they	they	PRON
fnp-3025	517	18	age	age	VERB
fnp-3025	517	19	,	,	PUNCT
fnp-3025	517	20	albeit	albeit	SCONJ
fnp-3025	517	21	fewer	few	ADJ
fnp-3025	517	22	than	than	ADP
fnp-3025	517	23	mice	mouse	NOUN
fnp-3025	517	24	raised	raise	VERB
fnp-3025	517	25	in	in	ADP
fnp-3025	517	26	normal	normal	ADJ
fnp-3025	517	27	caging	caging	NOUN
fnp-3025	517	28	[	[	X
fnp-3025	517	29	406	406	NUM
fnp-3025	517	30	]	]	PUNCT
fnp-3025	517	31	.	.	PUNCT
fnp-3025	518	1	with	with	ADP
fnp-3025	518	2	the	the	DET
fnp-3025	518	3	caveat	caveat	NOUN
fnp-3025	518	4	that	that	SCONJ
fnp-3025	518	5	the	the	DET
fnp-3025	518	6	mice	mouse	NOUN
fnp-3025	518	7	strongly	strongly	ADV
fnp-3025	518	8	overexpress	overexpress	ADJ
fnp-3025	518	9	transgenic	transgenic	NOUN
fnp-3025	518	10	aβ	aβ	NOUN
fnp-3025	518	11	,	,	PUNCT
fnp-3025	518	12	the	the	DET
fnp-3025	518	13	findings	finding	NOUN
fnp-3025	518	14	suggest	suggest	VERB
fnp-3025	518	15	that	that	SCONJ
fnp-3025	518	16	infection	infection	NOUN
fnp-3025	518	17	is	be	AUX
fnp-3025	518	18	not	not	PART
fnp-3025	518	19	required	require	VERB
fnp-3025	518	20	for	for	ADP
fnp-3025	518	21	plaque	plaque	NOUN
fnp-3025	518	22	formation	formation	NOUN
fnp-3025	518	23	,	,	PUNCT
fnp-3025	518	24	but	but	CCONJ
fnp-3025	518	25	that	that	SCONJ
fnp-3025	518	26	it	it	PRON
fnp-3025	518	27	can	can	AUX
fnp-3025	518	28	trigger	trigger	VERB
fnp-3025	518	29	and/or	and/or	CCONJ
fnp-3025	518	30	accelerate	accelerate	VERB
fnp-3025	518	31	the	the	DET
fnp-3025	518	32	process	process	NOUN
fnp-3025	518	33	.	.	PUNCT
fnp-3025	519	1	the	the	DET
fnp-3025	519	2	role	role	NOUN
fnp-3025	519	3	of	of	ADP
fnp-3025	519	4	infection	infection	NOUN
fnp-3025	519	5	in	in	ADP
fnp-3025	519	6	the	the	DET
fnp-3025	519	7	causation	causation	NOUN
fnp-3025	519	8	of	of	ADP
fnp-3025	519	9	aβ	aβ	DET
fnp-3025	519	10	plaques	plaque	NOUN
fnp-3025	519	11	and	and	CCONJ
fnp-3025	519	12	as	as	ADP
fnp-3025	519	13	a	a	DET
fnp-3025	519	14	risk	risk	NOUN
fnp-3025	519	15	factor	factor	NOUN
fnp-3025	519	16	for	for	ADP
fnp-3025	519	17	ad	ad	NOUN
fnp-3025	519	18	is	be	AUX
fnp-3025	519	19	an	an	DET
fnp-3025	519	20	intriguing	intriguing	ADJ
fnp-3025	519	21	topic	topic	NOUN
fnp-3025	519	22	with	with	ADP
fnp-3025	519	23	potential	potential	ADJ
fnp-3025	519	24	implications	implication	NOUN
fnp-3025	519	25	for	for	ADP
fnp-3025	519	26	prevention	prevention	NOUN
fnp-3025	519	27	and	and	CCONJ
fnp-3025	519	28	therapy	therapy	NOUN
fnp-3025	519	29	,	,	PUNCT
fnp-3025	519	30	but	but	CCONJ
fnp-3025	519	31	supporting	support	VERB
fnp-3025	519	32	evidence	evidence	NOUN
fnp-3025	519	33	for	for	ADP
fnp-3025	519	34	a	a	DET
fnp-3025	519	35	specific	specific	ADJ
fnp-3025	519	36	role	role	NOUN
fnp-3025	519	37	of	of	ADP
fnp-3025	519	38	specific	specific	ADJ
fnp-3025	519	39	microbes	microbe	NOUN
fnp-3025	519	40	in	in	ADP
fnp-3025	519	41	pathogenesis	pathogenesis	NOUN
fnp-3025	519	42	is	be	AUX
fnp-3025	519	43	needed	need	VERB
fnp-3025	519	44	.	.	PUNCT
fnp-3025	520	1	for	for	ADP
fnp-3025	520	2	a	a	DET
fnp-3025	520	3	critical	critical	ADJ
fnp-3025	520	4	consideration	consideration	NOUN
fnp-3025	520	5	of	of	ADP
fnp-3025	520	6	the	the	DET
fnp-3025	520	7	state	state	NOUN
fnp-3025	520	8	of	of	ADP
fnp-3025	520	9	the	the	DET
fnp-3025	520	10	field	field	NOUN
fnp-3025	520	11	,	,	PUNCT
fnp-3025	520	12	see	see	VERB
fnp-3025	520	13	[	[	X
fnp-3025	520	14	393	393	NUM
fnp-3025	520	15	]	]	PUNCT
fnp-3025	520	16	.	.	PUNCT
fnp-3025	521	1	14	14	NUM
fnp-3025	521	2	i	i	PRON
fnp-3025	521	3	use	use	VERB
fnp-3025	521	4	the	the	DET
fnp-3025	521	5	term	term	NOUN
fnp-3025	521	6	‘	'	PUNCT
fnp-3025	521	7	microbe	microbe	NOUN
fnp-3025	521	8	’	'	PUNCT
fnp-3025	521	9	here	here	ADV
fnp-3025	521	10	to	to	PART
fnp-3025	521	11	include	include	VERB
fnp-3025	521	12	both	both	PRON
fnp-3025	521	13	conventional	conventional	ADJ
fnp-3025	521	14	(	(	PUNCT
fnp-3025	521	15	living	living	NOUN
fnp-3025	521	16	)	)	PUNCT
fnp-3025	521	17	microorganisms	microorganism	NOUN
fnp-3025	521	18	and	and	CCONJ
fnp-3025	521	19	viruses	virus	NOUN
fnp-3025	521	20	(	(	PUNCT
fnp-3025	521	21	but	but	CCONJ
fnp-3025	521	22	not	not	PART
fnp-3025	521	23	prions	prion	NOUN
fnp-3025	521	24	)	)	PUNCT
fnp-3025	521	25	.	.	PUNCT
fnp-3025	522	1	9	9	X
fnp-3025	522	2	.	.	X
fnp-3025	522	3	the	the	DET
fnp-3025	522	4	seeded	seeded	ADJ
fnp-3025	522	5	induction	induction	NOUN
fnp-3025	522	6	of	of	ADP
fnp-3025	522	7	aβ	aβ	DET
fnp-3025	522	8	plaque	plaque	NOUN
fnp-3025	522	9	formation	formation	NOUN
fnp-3025	522	10	the	the	DET
fnp-3025	522	11	prion	prion	NOUN
fnp-3025	522	12	paradigm	paradigm	NOUN
fnp-3025	522	13	has	have	AUX
fnp-3025	522	14	become	become	VERB
fnp-3025	522	15	the	the	DET
fnp-3025	522	16	dominant	dominant	ADJ
fnp-3025	522	17	mechanistic	mechanistic	ADJ
fnp-3025	522	18	explanation	explanation	NOUN
fnp-3025	522	19	for	for	ADP
fnp-3025	522	20	the	the	DET
fnp-3025	522	21	aberrant	aberrant	ADJ
fnp-3025	522	22	self	self	NOUN
fnp-3025	522	23	-	-	PUNCT
fnp-3025	522	24	assembly	assembly	NOUN
fnp-3025	522	25	and	and	CCONJ
fnp-3025	522	26	propagation	propagation	NOUN
fnp-3025	522	27	of	of	ADP
fnp-3025	522	28	misfolded	misfolde	VERB
fnp-3025	522	29	proteins	protein	NOUN
fnp-3025	522	30	in	in	ADP
fnp-3025	522	31	the	the	DET
fnp-3025	522	32	brain	brain	NOUN
fnp-3025	522	33	and	and	CCONJ
fnp-3025	522	34	elsewhere	elsewhere	ADV
fnp-3025	522	35	in	in	ADP
fnp-3025	522	36	the	the	DET
fnp-3025	522	37	body	body	NOUN
fnp-3025	522	38	[	[	X
fnp-3025	522	39	58	58	NUM
fnp-3025	522	40	,	,	PUNCT
fnp-3025	522	41	205	205	NUM
fnp-3025	522	42	,	,	PUNCT
fnp-3025	522	43	218	218	NUM
fnp-3025	522	44	,	,	PUNCT
fnp-3025	522	45	407	407	NUM
fnp-3025	522	46	-	-	SYM
fnp-3025	522	47	409	409	NUM
fnp-3025	522	48	]	]	PUNCT
fnp-3025	522	49	.	.	PUNCT
fnp-3025	523	1	at	at	ADP
fnp-3025	523	2	the	the	DET
fnp-3025	523	3	molecular	molecular	ADJ
fnp-3025	523	4	level	level	NOUN
fnp-3025	523	5	,	,	PUNCT
fnp-3025	523	6	the	the	DET
fnp-3025	523	7	prion	prion	NOUN
fnp-3025	523	8	paradigm	paradigm	NOUN
fnp-3025	523	9	postulates	postulate	NOUN
fnp-3025	523	10	that	that	PRON
fnp-3025	523	11	misfolded	misfolde	VERB
fnp-3025	523	12	,	,	PUNCT
fnp-3025	523	13	β	β	NOUN
fnp-3025	523	14	-	-	ADJ
fnp-3025	523	15	sheet	sheet	NOUN
fnp-3025	523	16	-	-	PUNCT
fnp-3025	523	17	rich	rich	ADJ
fnp-3025	523	18	proteins	protein	NOUN
fnp-3025	523	19	aggregate	aggregate	VERB
fnp-3025	523	20	into	into	ADP
fnp-3025	523	21	oligomeric	oligomeric	ADJ
fnp-3025	523	22	/	/	SYM
fnp-3025	523	23	polymeric	polymeric	ADJ
fnp-3025	523	24	assemblies	assembly	NOUN
fnp-3025	523	25	that	that	PRON
fnp-3025	523	26	can	can	AUX
fnp-3025	523	27	induce	induce	VERB
fnp-3025	523	28	protein	protein	NOUN
fnp-3025	523	29	molecules	molecule	NOUN
fnp-3025	523	30	of	of	ADP
fnp-3025	523	31	the	the	DET
fnp-3025	523	32	same	same	ADJ
fnp-3025	523	33	type	type	NOUN
fnp-3025	523	34	to	to	PART
fnp-3025	523	35	adopt	adopt	VERB
fnp-3025	523	36	a	a	DET
fnp-3025	523	37	similar	similar	ADJ
fnp-3025	523	38	conformation	conformation	NOUN
fnp-3025	523	39	.	.	PUNCT
fnp-3025	524	1	in	in	ADP
fnp-3025	524	2	this	this	DET
fnp-3025	524	3	condition	condition	NOUN
fnp-3025	524	4	,	,	PUNCT
fnp-3025	524	5	the	the	DET
fnp-3025	524	6	proteins	protein	NOUN
fnp-3025	524	7	tend	tend	VERB
fnp-3025	524	8	to	to	PART
fnp-3025	524	9	stick	stick	VERB
fnp-3025	524	10	together	together	ADV
fnp-3025	524	11	,	,	PUNCT
fnp-3025	524	12	with	with	ADP
fnp-3025	524	13	the	the	DET
fnp-3025	524	14	assemblies	assembly	NOUN
fnp-3025	524	15	often	often	ADV
fnp-3025	524	16	(	(	PUNCT
fnp-3025	524	17	but	but	CCONJ
fnp-3025	524	18	not	not	PART
fnp-3025	524	19	always	always	ADV
fnp-3025	524	20	)	)	PUNCT
fnp-3025	524	21	amassing	amass	VERB
fnp-3025	524	22	into	into	ADP
fnp-3025	524	23	amyloid	amyloid	NOUN
fnp-3025	524	24	deposits	deposit	NOUN
fnp-3025	524	25	.	.	PUNCT
fnp-3025	525	1	in	in	ADP
fnp-3025	525	2	the	the	DET
fnp-3025	525	3	prion	prion	NOUN
fnp-3025	525	4	diseases	disease	NOUN
fnp-3025	525	5	,	,	PUNCT
fnp-3025	525	6	misfolded	misfolde	VERB
fnp-3025	525	7	prp	prp	PROPN
fnp-3025	525	8	self	self	NOUN
fnp-3025	525	9	-	-	PUNCT
fnp-3025	525	10	assembles	assemble	NOUN
fnp-3025	525	11	into	into	ADP
fnp-3025	525	12	highly	highly	ADV
fnp-3025	525	13	stable	stable	ADJ
fnp-3025	525	14	multimers	multimer	NOUN
fnp-3025	525	15	that	that	PRON
fnp-3025	525	16	are	be	AUX
fnp-3025	525	17	transmissible	transmissible	ADJ
fnp-3025	525	18	from	from	ADP
fnp-3025	525	19	one	one	NUM
fnp-3025	525	20	organism	organism	NOUN
fnp-3025	525	21	to	to	ADP
fnp-3025	525	22	another	another	PRON
fnp-3025	525	23	the	the	DET
fnp-3025	525	24	first	first	ADJ
fnp-3025	525	25	verified	verify	VERB
fnp-3025	525	26	instance	instance	NOUN
fnp-3025	525	27	of	of	ADP
fnp-3025	525	28	an	an	DET
fnp-3025	525	29	infectious	infectious	ADJ
fnp-3025	525	30	protein	protein	NOUN
fnp-3025	525	31	particle	particle	NOUN
fnp-3025	525	32	(	(	PUNCT
fnp-3025	525	33	‘	'	PUNCT
fnp-3025	525	34	prion	prion	NOUN
fnp-3025	525	35	’	'	PUNCT
fnp-3025	525	36	)	)	PUNCT
fnp-3025	526	1	[	[	X
fnp-3025	526	2	410	410	NUM
fnp-3025	526	3	,	,	PUNCT
fnp-3025	526	4	411	411	NUM
fnp-3025	526	5	]	]	PUNCT
fnp-3025	526	6	.	.	PUNCT
fnp-3025	527	1	human	human	ADJ
fnp-3025	527	2	prion	prion	NOUN
fnp-3025	527	3	diseases	disease	NOUN
fnp-3025	527	4	also	also	ADV
fnp-3025	527	5	originate	originate	VERB
fnp-3025	527	6	spontaneously	spontaneously	ADV
fnp-3025	527	7	or	or	CCONJ
fnp-3025	527	8	as	as	ADP
fnp-3025	527	9	a	a	DET
fnp-3025	527	10	result	result	NOUN
fnp-3025	527	11	of	of	ADP
fnp-3025	527	12	mutations	mutation	NOUN
fnp-3025	527	13	in	in	ADP
fnp-3025	527	14	the	the	DET
fnp-3025	527	15	gene	gene	NOUN
fnp-3025	527	16	for	for	ADP
fnp-3025	527	17	prp	prp	NOUN
fnp-3025	527	18	[	[	X
fnp-3025	527	19	412	412	NUM
fnp-3025	527	20	]	]	PUNCT
fnp-3025	527	21	.	.	PUNCT
fnp-3025	528	1	the	the	DET
fnp-3025	528	2	pathological	pathological	ADJ
fnp-3025	528	3	signature	signature	NOUN
fnp-3025	528	4	of	of	ADP
fnp-3025	528	5	the	the	DET
fnp-3025	528	6	prion	prion	NOUN
fnp-3025	528	7	diseases	disease	NOUN
fnp-3025	528	8	varies	vary	VERB
fnp-3025	528	9	considerably	considerably	ADV
fnp-3025	529	1	[	[	X
fnp-3025	529	2	127	127	NUM
fnp-3025	529	3	,	,	PUNCT
fnp-3025	529	4	128	128	NUM
fnp-3025	529	5	]	]	PUNCT
fnp-3025	529	6	,	,	PUNCT
fnp-3025	529	7	but	but	CCONJ
fnp-3025	529	8	,	,	PUNCT
fnp-3025	529	9	as	as	ADP
fnp-3025	529	10	in	in	ADP
fnp-3025	529	11	ad	ad	NOUN
fnp-3025	529	12	,	,	PUNCT
fnp-3025	529	13	the	the	DET
fnp-3025	529	14	universal	universal	ADJ
fnp-3025	529	15	feature	feature	NOUN
fnp-3025	529	16	of	of	ADP
fnp-3025	529	17	prionopathies	prionopathie	NOUN
fnp-3025	529	18	is	be	AUX
fnp-3025	529	19	the	the	DET
fnp-3025	529	20	accumulation	accumulation	NOUN
fnp-3025	529	21	of	of	ADP
fnp-3025	529	22	an	an	DET
fnp-3025	529	23	abnormally	abnormally	ADV
fnp-3025	529	24	folded	fold	VERB
fnp-3025	529	25	protein	protein	NOUN
fnp-3025	529	26	in	in	ADP
fnp-3025	529	27	this	this	DET
fnp-3025	529	28	case	case	NOUN
fnp-3025	529	29	prp	prp	NOUN
fnp-3025	529	30	in	in	ADP
fnp-3025	529	31	the	the	DET
fnp-3025	529	32	nervous	nervous	ADJ
fnp-3025	529	33	system	system	NOUN
fnp-3025	529	34	.	.	PUNCT
fnp-3025	530	1	systematic	systematic	ADJ
fnp-3025	530	2	studies	study	NOUN
fnp-3025	530	3	in	in	ADP
fnp-3025	530	4	transgenic	transgenic	NOUN
fnp-3025	530	5	mouse	mouse	NOUN
fnp-3025	530	6	models	model	NOUN
fnp-3025	530	7	expressing	express	VERB
fnp-3025	530	8	human	human	ADJ
fnp-3025	530	9	app	app	NOUN
fnp-3025	530	10	have	have	AUX
fnp-3025	530	11	determined	determine	VERB
fnp-3025	530	12	that	that	SCONJ
fnp-3025	530	13	aβ	aβ	PRON
fnp-3025	530	14	plaque	plaque	NOUN
fnp-3025	530	15	formation	formation	NOUN
fnp-3025	530	16	is	be	AUX
fnp-3025	530	17	driven	drive	VERB
fnp-3025	530	18	by	by	ADP
fnp-3025	530	19	a	a	DET
fnp-3025	530	20	molecular	molecular	ADJ
fnp-3025	530	21	process	process	NOUN
fnp-3025	530	22	that	that	PRON
fnp-3025	530	23	is	be	AUX
fnp-3025	530	24	indistinguishable	indistinguishable	ADJ
fnp-3025	530	25	from	from	ADP
fnp-3025	530	26	the	the	DET
fnp-3025	530	27	mechanism	mechanism	NOUN
fnp-3025	530	28	by	by	ADP
fnp-3025	530	29	which	which	PRON
fnp-3025	530	30	prions	prion	NOUN
fnp-3025	530	31	instigate	instigate	VERB
fnp-3025	530	32	disease	disease	NOUN
fnp-3025	530	33	[	[	X
fnp-3025	530	34	217	217	NUM
fnp-3025	530	35	,	,	PUNCT
fnp-3025	530	36	218	218	NUM
fnp-3025	530	37	,	,	PUNCT
fnp-3025	530	38	413	413	NUM
fnp-3025	530	39	-	-	SYM
fnp-3025	530	40	415	415	NUM
fnp-3025	530	41	]	]	PUNCT
fnp-3025	530	42	(	(	PUNCT
fnp-3025	530	43	figure	figure	NOUN
fnp-3025	530	44	21	21	NUM
fnp-3025	530	45	)	)	PUNCT
fnp-3025	530	46	.	.	PUNCT
fnp-3025	531	1	in	in	ADP
fnp-3025	531	2	this	this	DET
fnp-3025	531	3	paradigm	paradigm	NOUN
fnp-3025	531	4	,	,	PUNCT
fnp-3025	531	5	brain	brain	NOUN
fnp-3025	531	6	extracts	extract	NOUN
fnp-3025	531	7	containing	contain	VERB
fnp-3025	531	8	aggregated	aggregate	VERB
fnp-3025	531	9	aβ	aβ	NUM
fnp-3025	531	10	are	be	AUX
fnp-3025	531	11	infused	infuse	VERB
fnp-3025	531	12	into	into	ADP
fnp-3025	531	13	the	the	DET
fnp-3025	531	14	brains	brain	NOUN
fnp-3025	531	15	of	of	ADP
fnp-3025	531	16	susceptible	susceptible	ADJ
fnp-3025	531	17	mice	mouse	NOUN
fnp-3025	531	18	,	,	PUNCT
fnp-3025	531	19	instigating	instigate	VERB
fnp-3025	531	20	aβ	aβ	PRON
fnp-3025	531	21	plaque	plaque	NOUN
fnp-3025	531	22	development	development	NOUN
fnp-3025	531	23	in	in	ADP
fnp-3025	531	24	a	a	DET
fnp-3025	531	25	model-	model-	NOUN
fnp-3025	531	26	,	,	PUNCT
fnp-3025	531	27	doseand	doseand	VERB
fnp-3025	531	28	time	time	NOUN
fnp-3025	531	29	-	-	PUNCT
fnp-3025	531	30	dependent	dependent	ADJ
fnp-3025	531	31	fashion	fashion	NOUN
fnp-3025	532	1	[	[	X
fnp-3025	532	2	218	218	NUM
fnp-3025	532	3	,	,	PUNCT
fnp-3025	532	4	407	407	NUM
fnp-3025	532	5	]	]	PUNCT
fnp-3025	532	6	.	.	PUNCT
fnp-3025	533	1	analyses	analysis	NOUN
fnp-3025	533	2	of	of	ADP
fnp-3025	533	3	seeded	seeded	ADJ
fnp-3025	533	4	aggregation	aggregation	NOUN
fnp-3025	533	5	in	in	ADP
fnp-3025	533	6	experimental	experimental	ADJ
fnp-3025	533	7	systems	system	NOUN
fnp-3025	533	8	have	have	AUX
fnp-3025	533	9	demonstrated	demonstrate	VERB
fnp-3025	533	10	that	that	SCONJ
fnp-3025	533	11	aβ	aβ	PRON
fnp-3025	533	12	seeds	seed	NOUN
fnp-3025	533	13	share	share	VERB
fnp-3025	533	14	key	key	ADJ
fnp-3025	533	15	properties	property	NOUN
fnp-3025	533	16	with	with	ADP
fnp-3025	533	17	prions	prion	NOUN
fnp-3025	533	18	:	:	PUNCT
fnp-3025	533	19	1	1	X
fnp-3025	533	20	)	)	PUNCT
fnp-3025	533	21	they	they	PRON
fnp-3025	533	22	are	be	AUX
fnp-3025	533	23	protein	protein	NOUN
fnp-3025	533	24	-	-	PUNCT
fnp-3025	533	25	only	only	ADJ
fnp-3025	533	26	agents	agent	NOUN
fnp-3025	533	27	that	that	PRON
fnp-3025	533	28	are	be	AUX
fnp-3025	533	29	resistant	resistant	ADJ
fnp-3025	533	30	to	to	ADP
fnp-3025	533	31	destruction	destruction	NOUN
fnp-3025	533	32	by	by	ADP
fnp-3025	533	33	heat	heat	NOUN
fnp-3025	533	34	and	and	CCONJ
fnp-3025	533	35	formaldehyde	formaldehyde	NOUN
fnp-3025	533	36	;	;	PUNCT
fnp-3025	533	37	2	2	X
fnp-3025	533	38	)	)	PUNCT
fnp-3025	533	39	they	they	PRON
fnp-3025	533	40	incite	incite	VERB
fnp-3025	533	41	the	the	DET
fnp-3025	533	42	formation	formation	NOUN
fnp-3025	533	43	of	of	ADP
fnp-3025	533	44	cerebral	cerebral	ADJ
fnp-3025	533	45	aβ	aβ	NOUN
fnp-3025	533	46	plaques	plaque	NOUN
fnp-3025	533	47	and	and	CCONJ
fnp-3025	533	48	aβ	aβ	NOUN
fnp-3025	533	49	-	-	PUNCT
fnp-3025	533	50	amyloid	amyloid	NOUN
fnp-3025	533	51	angiopathy	angiopathy	NOUN
fnp-3025	533	52	when	when	SCONJ
fnp-3025	533	53	introduced	introduce	VERB
fnp-3025	533	54	into	into	ADP
fnp-3025	533	55	the	the	DET
fnp-3025	533	56	brain	brain	NOUN
fnp-3025	533	57	or	or	CCONJ
fnp-3025	533	58	into	into	ADP
fnp-3025	533	59	the	the	DET
fnp-3025	533	60	periphery	periphery	NOUN
fnp-3025	533	61	;	;	PUNCT
fnp-3025	533	62	3	3	X
fnp-3025	533	63	)	)	PUNCT
fnp-3025	533	64	they	they	PRON
fnp-3025	533	65	exist	exist	VERB
fnp-3025	533	66	in	in	ADP
fnp-3025	533	67	multiple	multiple	ADJ
fnp-3025	533	68	sizes	size	NOUN
fnp-3025	533	69	;	;	PUNCT
fnp-3025	533	70	and	and	CCONJ
fnp-3025	533	71	4	4	X
fnp-3025	533	72	)	)	PUNCT
fnp-3025	533	73	they	they	PRON
fnp-3025	533	74	can	can	AUX
fnp-3025	533	75	fold	fold	VERB
fnp-3025	533	76	into	into	ADP
fnp-3025	533	77	different	different	ADJ
fnp-3025	533	78	molecular	molecular	ADJ
fnp-3025	533	79	variants	variant	NOUN
fnp-3025	533	80	referred	refer	VERB
fnp-3025	533	81	to	to	ADP
fnp-3025	533	82	as	as	ADP
fnp-3025	533	83	proteopathic	proteopathic	ADJ
fnp-3025	533	84	strains	strain	NOUN
fnp-3025	533	85	[	[	X
fnp-3025	533	86	212	212	NUM
fnp-3025	533	87	,	,	PUNCT
fnp-3025	533	88	213	213	NUM
fnp-3025	533	89	,	,	PUNCT
fnp-3025	533	90	217	217	NUM
fnp-3025	533	91	,	,	PUNCT
fnp-3025	533	92	218	218	NUM
fnp-3025	533	93	,	,	PUNCT
fnp-3025	533	94	407	407	NUM
fnp-3025	533	95	]	]	PUNCT
fnp-3025	533	96	(	(	PUNCT
fnp-3025	533	97	see	see	VERB
fnp-3025	533	98	section	section	NOUN
fnp-3025	533	99	5.2	5.2	NUM
fnp-3025	533	100	)	)	PUNCT
fnp-3025	533	101	.	.	PUNCT
fnp-3025	534	1	the	the	DET
fnp-3025	534	2	strain	strain	NOUN
fnp-3025	534	3	-	-	PUNCT
fnp-3025	534	4	like	like	ADJ
fnp-3025	534	5	properties	property	NOUN
fnp-3025	534	6	of	of	ADP
fnp-3025	534	7	aβ	aβ	PRON
fnp-3025	534	8	deriving	derive	VERB
fnp-3025	534	9	from	from	ADP
fnp-3025	534	10	different	different	ADJ
fnp-3025	534	11	subtypes	subtype	NOUN
fnp-3025	534	12	of	of	ADP
fnp-3025	534	13	ad	ad	NOUN
fnp-3025	534	14	can	can	AUX
fnp-3025	534	15	be	be	AUX
fnp-3025	534	16	partially	partially	ADV
fnp-3025	534	17	transmitted	transmit	VERB
fnp-3025	534	18	to	to	ADP
fnp-3025	534	19	plaques	plaque	NOUN
fnp-3025	534	20	via	via	ADP
fnp-3025	534	21	exogenous	exogenous	ADJ
fnp-3025	534	22	seeding	seeding	NOUN
fnp-3025	534	23	in	in	ADP
fnp-3025	534	24	mouse	mouse	NOUN
fnp-3025	534	25	models	model	NOUN
fnp-3025	534	26	[	[	X
fnp-3025	534	27	227	227	NUM
fnp-3025	534	28	,	,	PUNCT
fnp-3025	534	29	230	230	NUM
fnp-3025	534	30	]	]	PUNCT
fnp-3025	534	31	.	.	PUNCT
fnp-3025	535	1	figure	figure	NOUN
fnp-3025	535	2	21	21	NUM
fnp-3025	535	3	.	.	PUNCT
fnp-3025	536	1	seeded	seed	VERB
fnp-3025	536	2	aβ	aβ	NOUN
fnp-3025	536	3	deposition	deposition	NOUN
fnp-3025	536	4	in	in	ADP
fnp-3025	536	5	the	the	DET
fnp-3025	536	6	hippocampal	hippocampal	ADJ
fnp-3025	536	7	formation	formation	NOUN
fnp-3025	536	8	of	of	ADP
fnp-3025	536	9	a	a	DET
fnp-3025	536	10	tg2576	tg2576	PROPN
fnp-3025	536	11	app	app	ADJ
fnp-3025	536	12	-	-	PUNCT
fnp-3025	536	13	transgenic	transgenic	ADJ
fnp-3025	536	14	mouse	mouse	NOUN
fnp-3025	536	15	5	5	NUM
fnp-3025	536	16	-	-	PUNCT
fnp-3025	536	17	months	month	NOUN
fnp-3025	536	18	following	follow	VERB
fnp-3025	536	19	unilateral	unilateral	ADJ
fnp-3025	536	20	injection	injection	NOUN
fnp-3025	536	21	of	of	ADP
fnp-3025	536	22	dilute	dilute	ADJ
fnp-3025	536	23	ad	ad	NOUN
fnp-3025	536	24	brain	brain	NOUN
fnp-3025	536	25	extract	extract	NOUN
fnp-3025	536	26	into	into	ADP
fnp-3025	536	27	one	one	NUM
fnp-3025	536	28	hemisphere	hemisphere	NOUN
fnp-3025	536	29	(	(	PUNCT
fnp-3025	536	30	left	left	ADV
fnp-3025	536	31	)	)	PUNCT
fnp-3025	536	32	.	.	PUNCT
fnp-3025	537	1	the	the	DET
fnp-3025	537	2	contralateral	contralateral	ADJ
fnp-3025	537	3	hippocampus	hippocampus	NOUN
fnp-3025	537	4	in	in	ADP
fnp-3025	537	5	the	the	DET
fnp-3025	537	6	same	same	ADJ
fnp-3025	537	7	tissue	tissue	NOUN
fnp-3025	537	8	section	section	NOUN
fnp-3025	537	9	is	be	AUX
fnp-3025	537	10	on	on	ADP
fnp-3025	537	11	the	the	DET
fnp-3025	537	12	right	right	NOUN
fnp-3025	537	13	.	.	PUNCT
fnp-3025	538	1	antibody	antibody	NOUN
fnp-3025	538	2	4g8	4g8	NUM
fnp-3025	538	3	;	;	PUNCT
fnp-3025	538	4	bar	bar	NOUN
fnp-3025	538	5	=	=	SYM
fnp-3025	538	6	100μm	100μm	NOUN
fnp-3025	538	7	.	.	PUNCT
fnp-3025	539	1	these	these	DET
fnp-3025	539	2	investigations	investigation	NOUN
fnp-3025	539	3	highlight	highlight	VERB
fnp-3025	539	4	the	the	DET
fnp-3025	539	5	prion	prion	NOUN
fnp-3025	539	6	-	-	PUNCT
fnp-3025	539	7	like	like	ADJ
fnp-3025	539	8	seeded	seeded	ADJ
fnp-3025	539	9	aggregation	aggregation	NOUN
fnp-3025	539	10	of	of	ADP
fnp-3025	539	11	aβ	aβ	PRON
fnp-3025	539	12	as	as	ADP
fnp-3025	539	13	the	the	DET
fnp-3025	539	14	propulsive	propulsive	ADJ
fnp-3025	539	15	mechanism	mechanism	NOUN
fnp-3025	539	16	behind	behind	ADP
fnp-3025	539	17	the	the	DET
fnp-3025	539	18	formation	formation	NOUN
fnp-3025	539	19	of	of	ADP
fnp-3025	539	20	aβ	aβ	DET
fnp-3025	539	21	plaques	plaque	NOUN
fnp-3025	539	22	.	.	PUNCT
fnp-3025	540	1	since	since	SCONJ
fnp-3025	540	2	there	there	PRON
fnp-3025	540	3	is	be	VERB
fnp-3025	540	4	currently	currently	ADV
fnp-3025	540	5	no	no	DET
fnp-3025	540	6	evidence	evidence	NOUN
fnp-3025	540	7	that	that	SCONJ
fnp-3025	540	8	ad	ad	NOUN
fnp-3025	540	9	or	or	CCONJ
fnp-3025	540	10	other	other	ADJ
fnp-3025	540	11	cerebral	cerebral	ADJ
fnp-3025	540	12	proteopathies	proteopathie	NOUN
fnp-3025	540	13	are	be	AUX
fnp-3025	540	14	infectious	infectious	ADJ
fnp-3025	540	15	under	under	ADP
fnp-3025	540	16	ordinary	ordinary	ADJ
fnp-3025	540	17	circumstances	circumstance	NOUN
fnp-3025	540	18	[	[	X
fnp-3025	540	19	416	416	NUM
fnp-3025	540	20	,	,	PUNCT
fnp-3025	540	21	417	417	NUM
fnp-3025	540	22	]	]	PUNCT
fnp-3025	540	23	,	,	PUNCT
fnp-3025	540	24	it	it	PRON
fnp-3025	540	25	is	be	AUX
fnp-3025	540	26	likely	likely	ADJ
fnp-3025	540	27	that	that	SCONJ
fnp-3025	540	28	plaques	plaque	NOUN
fnp-3025	540	29	ordinarily	ordinarily	ADV
fnp-3025	540	30	arise	arise	VERB
fnp-3025	540	31	endogenously	endogenously	ADV
fnp-3025	540	32	with	with	ADP
fnp-3025	540	33	the	the	DET
fnp-3025	540	34	stochastic	stochastic	ADJ
fnp-3025	540	35	emergence	emergence	NOUN
fnp-3025	540	36	,	,	PUNCT
fnp-3025	540	37	persistence	persistence	NOUN
fnp-3025	540	38	and	and	CCONJ
fnp-3025	540	39	spread	spread	NOUN
fnp-3025	540	40	of	of	ADP
fnp-3025	540	41	aβ	aβ	ADP
fnp-3025	540	42	seeds	seed	NOUN
fnp-3025	540	43	.	.	PUNCT
fnp-3025	541	1	this	this	DET
fnp-3025	541	2	process	process	NOUN
fnp-3025	541	3	can	can	AUX
fnp-3025	541	4	be	be	AUX
fnp-3025	541	5	advanced	advance	VERB
fnp-3025	541	6	by	by	ADP
fnp-3025	541	7	various	various	ADJ
fnp-3025	541	8	environmental	environmental	ADJ
fnp-3025	541	9	and	and	CCONJ
fnp-3025	541	10	endogenous	endogenous	ADJ
fnp-3025	541	11	risk	risk	NOUN
fnp-3025	541	12	factors	factor	NOUN
fnp-3025	541	13	that	that	PRON
fnp-3025	541	14	influence	influence	VERB
fnp-3025	541	15	the	the	DET
fnp-3025	541	16	likelihood	likelihood	NOUN
fnp-3025	541	17	that	that	SCONJ
fnp-3025	541	18	aβ	aβ	PRON
fnp-3025	541	19	will	will	AUX
fnp-3025	541	20	misfold	misfold	VERB
fnp-3025	541	21	and	and	CCONJ
fnp-3025	541	22	propagate	propagate	VERB
fnp-3025	541	23	in	in	ADP
fnp-3025	541	24	the	the	DET
fnp-3025	541	25	brain	brain	NOUN
fnp-3025	542	1	[	[	X
fnp-3025	542	2	45	45	NUM
fnp-3025	542	3	]	]	PUNCT
fnp-3025	542	4	.	.	PUNCT
fnp-3025	543	1	under	under	ADP
fnp-3025	543	2	extraordinary	extraordinary	ADJ
fnp-3025	543	3	circumstances	circumstance	NOUN
fnp-3025	543	4	,	,	PUNCT
fnp-3025	543	5	however	however	ADV
fnp-3025	543	6	,	,	PUNCT
fnp-3025	543	7	aβ	aβ	ADP
fnp-3025	543	8	plaques	plaque	NOUN
fnp-3025	543	9	and	and	CCONJ
fnp-3025	543	10	aβ	aβ	NOUN
fnp-3025	543	11	-	-	PUNCT
fnp-3025	543	12	caa	caa	NOUN
fnp-3025	543	13	can	can	AUX
fnp-3025	543	14	be	be	AUX
fnp-3025	543	15	instigated	instigate	VERB
fnp-3025	543	16	by	by	ADP
fnp-3025	543	17	exogenous	exogenous	ADJ
fnp-3025	543	18	aβ	aβ	NOUN
fnp-3025	543	19	seeds	seed	NOUN
fnp-3025	543	20	in	in	ADP
fnp-3025	543	21	humans	human	NOUN
fnp-3025	543	22	[	[	X
fnp-3025	543	23	417	417	NUM
fnp-3025	543	24	]	]	PUNCT
fnp-3025	543	25	.	.	PUNCT
fnp-3025	544	1	treatment	treatment	NOUN
fnp-3025	544	2	of	of	ADP
fnp-3025	544	3	young	young	ADJ
fnp-3025	544	4	people	people	NOUN
fnp-3025	544	5	with	with	ADP
fnp-3025	544	6	growth	growth	NOUN
fnp-3025	544	7	hormone	hormone	NOUN
fnp-3025	544	8	derived	derive	VERB
fnp-3025	544	9	from	from	ADP
fnp-3025	544	10	cadaveric	cadaveric	ADJ
fnp-3025	544	11	human	human	ADJ
fnp-3025	544	12	pituitary	pituitary	ADJ
fnp-3025	544	13	glands	gland	NOUN
fnp-3025	544	14	,	,	PUNCT
fnp-3025	544	15	beginning	begin	VERB
fnp-3025	544	16	in	in	ADP
fnp-3025	544	17	the	the	DET
fnp-3025	544	18	late	late	ADJ
fnp-3025	544	19	1950s	1950s	NUM
fnp-3025	544	20	,	,	PUNCT
fnp-3025	544	21	resulted	result	VERB
fnp-3025	544	22	unexpectedly	unexpectedly	ADV
fnp-3025	544	23	in	in	ADP
fnp-3025	544	24	the	the	DET
fnp-3025	544	25	development	development	NOUN
fnp-3025	544	26	of	of	ADP
fnp-3025	544	27	prion	prion	NOUN
fnp-3025	544	28	disease	disease	NOUN
fnp-3025	544	29	(	(	PUNCT
fnp-3025	544	30	creutzfeldt	creutzfeldt	ADJ
fnp-3025	544	31	-	-	PUNCT
fnp-3025	544	32	jakob	jakob	ADJ
fnp-3025	544	33	disease	disease	NOUN
fnp-3025	544	34	)	)	PUNCT
fnp-3025	544	35	many	many	ADJ
fnp-3025	544	36	years	year	NOUN
fnp-3025	544	37	later	later	ADV
fnp-3025	544	38	[	[	X
fnp-3025	544	39	418	418	NUM
fnp-3025	544	40	,	,	PUNCT
fnp-3025	544	41	419	419	NUM
fnp-3025	544	42	]	]	PUNCT
fnp-3025	544	43	.	.	PUNCT
fnp-3025	545	1	the	the	DET
fnp-3025	545	2	apparent	apparent	ADJ
fnp-3025	545	3	cause	cause	NOUN
fnp-3025	545	4	was	be	AUX
fnp-3025	545	5	the	the	DET
fnp-3025	545	6	presence	presence	NOUN
fnp-3025	545	7	of	of	ADP
fnp-3025	545	8	infectious	infectious	ADJ
fnp-3025	545	9	prions	prion	NOUN
fnp-3025	545	10	in	in	ADP
fnp-3025	545	11	the	the	DET
fnp-3025	545	12	preparations	preparation	NOUN
fnp-3025	545	13	,	,	PUNCT
fnp-3025	545	14	probably	probably	ADV
fnp-3025	545	15	because	because	SCONJ
fnp-3025	545	16	the	the	DET
fnp-3025	545	17	large	large	ADJ
fnp-3025	545	18	batches	batch	NOUN
fnp-3025	545	19	of	of	ADP
fnp-3025	545	20	pituitaries	pituitary	NOUN
fnp-3025	545	21	that	that	PRON
fnp-3025	545	22	were	be	AUX
fnp-3025	545	23	homogenized	homogenize	VERB
fnp-3025	545	24	for	for	ADP
fnp-3025	545	25	extraction	extraction	NOUN
fnp-3025	545	26	of	of	ADP
fnp-3025	545	27	growth	growth	NOUN
fnp-3025	545	28	hormone	hormone	NOUN
fnp-3025	545	29	contained	contain	VERB
fnp-3025	545	30	some	some	DET
fnp-3025	545	31	glands	gland	NOUN
fnp-3025	545	32	from	from	ADP
fnp-3025	545	33	decedents	decedent	NOUN
fnp-3025	545	34	with	with	ADP
fnp-3025	545	35	prion	prion	NOUN
fnp-3025	545	36	disease	disease	NOUN
fnp-3025	545	37	.	.	PUNCT
fnp-3025	546	1	researchers	researcher	NOUN
fnp-3025	546	2	in	in	ADP
fnp-3025	546	3	england	england	PROPN
fnp-3025	546	4	later	later	ADV
fnp-3025	546	5	found	find	VERB
fnp-3025	546	6	that	that	SCONJ
fnp-3025	546	7	both	both	PRON
fnp-3025	546	8	aβ	aβ	ADP
fnp-3025	546	9	plaques	plaque	NOUN
fnp-3025	546	10	and	and	CCONJ
fnp-3025	546	11	aβ	aβ	NOUN
fnp-3025	546	12	-	-	PUNCT
fnp-3025	546	13	caa	caa	NOUN
fnp-3025	546	14	were	be	AUX
fnp-3025	546	15	much	much	ADV
fnp-3025	546	16	more	more	ADV
fnp-3025	546	17	common	common	ADJ
fnp-3025	546	18	in	in	ADP
fnp-3025	546	19	human	human	ADJ
fnp-3025	546	20	growth	growth	NOUN
fnp-3025	546	21	hormone	hormone	NOUN
fnp-3025	546	22	-	-	PUNCT
fnp-3025	546	23	treated	treat	VERB
fnp-3025	546	24	subjects	subject	NOUN
fnp-3025	546	25	than	than	ADP
fnp-3025	546	26	in	in	ADP
fnp-3025	546	27	non	non	ADJ
fnp-3025	546	28	-	-	ADJ
fnp-3025	546	29	treated	treat	VERB
fnp-3025	546	30	controls	control	NOUN
fnp-3025	546	31	[	[	X
fnp-3025	546	32	420	420	NUM
fnp-3025	546	33	]	]	PUNCT
fnp-3025	546	34	.	.	PUNCT
fnp-3025	547	1	furthermore	furthermore	ADV
fnp-3025	547	2	,	,	PUNCT
fnp-3025	547	3	aβ	aβ	DET
fnp-3025	547	4	deposition	deposition	NOUN
fnp-3025	547	5	was	be	AUX
fnp-3025	547	6	precipitated	precipitate	VERB
fnp-3025	547	7	both	both	CCONJ
fnp-3025	547	8	in	in	ADP
fnp-3025	547	9	growth	growth	NOUN
fnp-3025	547	10	hormone	hormone	NOUN
fnp-3025	547	11	recipients	recipient	NOUN
fnp-3025	547	12	dying	die	VERB
fnp-3025	547	13	with	with	ADP
fnp-3025	547	14	[	[	X
fnp-3025	547	15	420	420	NUM
fnp-3025	547	16	]	]	PUNCT
fnp-3025	547	17	or	or	CCONJ
fnp-3025	547	18	without	without	ADP
fnp-3025	547	19	[	[	X
fnp-3025	547	20	421	421	NUM
fnp-3025	547	21	]	]	X
fnp-3025	547	22	creutzfeldt	creutzfeldt	ADJ
fnp-3025	547	23	-	-	PUNCT
fnp-3025	547	24	jakob	jakob	ADJ
fnp-3025	547	25	disease	disease	NOUN
fnp-3025	547	26	.	.	PUNCT
fnp-3025	548	1	an	an	DET
fnp-3025	548	2	increase	increase	NOUN
fnp-3025	548	3	in	in	ADP
fnp-3025	548	4	aβ	aβ	NOUN
fnp-3025	548	5	-	-	PUNCT
fnp-3025	548	6	proteopathy	proteopathy	ADJ
fnp-3025	548	7	also	also	ADV
fnp-3025	548	8	has	have	AUX
fnp-3025	548	9	been	be	AUX
fnp-3025	548	10	reported	report	VERB
fnp-3025	548	11	in	in	ADP
fnp-3025	548	12	a	a	DET
fnp-3025	548	13	subset	subset	NOUN
fnp-3025	548	14	of	of	ADP
fnp-3025	548	15	people	people	NOUN
fnp-3025	548	16	who	who	PRON
fnp-3025	548	17	had	have	AUX
fnp-3025	548	18	received	receive	VERB
fnp-3025	548	19	cadaveric	cadaveric	ADJ
fnp-3025	548	20	dura	dura	NOUN
fnp-3025	548	21	mater	mater	NOUN
fnp-3025	548	22	transplants	transplant	NOUN
fnp-3025	548	23	[	[	X
fnp-3025	548	24	422	422	NUM
fnp-3025	548	25	,	,	PUNCT
fnp-3025	548	26	423	423	NUM
fnp-3025	548	27	]	]	PUNCT
fnp-3025	548	28	.	.	PUNCT
fnp-3025	549	1	the	the	DET
fnp-3025	549	2	most	most	ADV
fnp-3025	549	3	parsimonious	parsimonious	ADJ
fnp-3025	549	4	explanation	explanation	NOUN
fnp-3025	549	5	for	for	ADP
fnp-3025	549	6	these	these	DET
fnp-3025	549	7	findings	finding	NOUN
fnp-3025	549	8	is	be	AUX
fnp-3025	549	9	that	that	SCONJ
fnp-3025	549	10	some	some	DET
fnp-3025	549	11	batches	batch	NOUN
fnp-3025	549	12	of	of	ADP
fnp-3025	549	13	therapeutic	therapeutic	ADJ
fnp-3025	549	14	growth	growth	NOUN
fnp-3025	549	15	hormone	hormone	NOUN
fnp-3025	549	16	and	and	CCONJ
fnp-3025	549	17	dura	dura	NOUN
fnp-3025	549	18	mater	mater	NOUN
fnp-3025	549	19	were	be	AUX
fnp-3025	549	20	tainted	taint	VERB
fnp-3025	549	21	by	by	ADP
fnp-3025	549	22	aβ	aβ	DET
fnp-3025	549	23	seeds	seed	NOUN
fnp-3025	549	24	that	that	PRON
fnp-3025	549	25	were	be	AUX
fnp-3025	549	26	present	present	ADJ
fnp-3025	549	27	in	in	ADP
fnp-3025	549	28	the	the	DET
fnp-3025	549	29	tissues	tissue	NOUN
fnp-3025	549	30	taken	take	VERB
fnp-3025	549	31	from	from	ADP
fnp-3025	549	32	donors	donor	NOUN
fnp-3025	549	33	with	with	ADP
fnp-3025	549	34	ad	ad	NOUN
fnp-3025	549	35	(	(	PUNCT
fnp-3025	549	36	or	or	CCONJ
fnp-3025	549	37	incipient	incipient	ADJ
fnp-3025	549	38	ad	ad	NOUN
fnp-3025	549	39	)	)	PUNCT
fnp-3025	550	1	[	[	X
fnp-3025	550	2	417	417	NUM
fnp-3025	550	3	]	]	PUNCT
fnp-3025	550	4	.	.	PUNCT
fnp-3025	551	1	this	this	DET
fnp-3025	551	2	possibility	possibility	NOUN
fnp-3025	551	3	is	be	AUX
fnp-3025	551	4	reinforced	reinforce	VERB
fnp-3025	551	5	by	by	ADP
fnp-3025	551	6	the	the	DET
fnp-3025	551	7	demonstrable	demonstrable	ADJ
fnp-3025	551	8	presence	presence	NOUN
fnp-3025	551	9	of	of	ADP
fnp-3025	551	10	aggregated	aggregate	VERB
fnp-3025	551	11	aβ	aβ	NOUN
fnp-3025	551	12	in	in	ADP
fnp-3025	551	13	some	some	DET
fnp-3025	551	14	pituitary	pituitary	ADJ
fnp-3025	551	15	glands	gland	NOUN
fnp-3025	551	16	[	[	X
fnp-3025	551	17	424	424	NUM
fnp-3025	551	18	]	]	PUNCT
fnp-3025	551	19	and	and	CCONJ
fnp-3025	551	20	dura	dura	NOUN
fnp-3025	551	21	mater	mater	NOUN
fnp-3025	551	22	[	[	NOUN
fnp-3025	551	23	425	425	NUM
fnp-3025	551	24	]	]	PUNCT
fnp-3025	551	25	from	from	ADP
fnp-3025	551	26	ad	ad	NOUN
fnp-3025	551	27	patients	patient	NOUN
fnp-3025	551	28	.	.	PUNCT
fnp-3025	552	1	furthermore	furthermore	ADV
fnp-3025	552	2	,	,	PUNCT
fnp-3025	552	3	aβ	aβ	PRON
fnp-3025	552	4	was	be	AUX
fnp-3025	552	5	detected	detect	VERB
fnp-3025	552	6	in	in	ADP
fnp-3025	552	7	archival	archival	NOUN
fnp-3025	552	8	samples	sample	NOUN
fnp-3025	552	9	of	of	ADP
fnp-3025	552	10	cadaveric	cadaveric	ADJ
fnp-3025	552	11	human	human	ADJ
fnp-3025	552	12	growth	growth	NOUN
fnp-3025	552	13	hormone	hormone	NOUN
fnp-3025	553	1	[	[	X
fnp-3025	553	2	426	426	NUM
fnp-3025	553	3	]	]	X
fnp-3025	553	4	,	,	PUNCT
fnp-3025	553	5	and	and	CCONJ
fnp-3025	553	6	stored	store	VERB
fnp-3025	553	7	hormone	hormone	NOUN
fnp-3025	553	8	was	be	AUX
fnp-3025	553	9	shown	show	VERB
fnp-3025	553	10	to	to	PART
fnp-3025	553	11	stimulate	stimulate	VERB
fnp-3025	553	12	cerebral	cerebral	ADJ
fnp-3025	554	1	aβ	aβ	NOUN
fnp-3025	554	2	deposition	deposition	NOUN
fnp-3025	554	3	when	when	SCONJ
fnp-3025	554	4	injected	inject	VERB
fnp-3025	554	5	intracerebrally	intracerebrally	ADV
fnp-3025	554	6	into	into	ADP
fnp-3025	554	7	app	app	ADJ
fnp-3025	554	8	-	-	PUNCT
fnp-3025	554	9	transgenic	transgenic	NOUN
fnp-3025	554	10	mice	mouse	NOUN
fnp-3025	555	1	[	[	X
fnp-3025	555	2	427	427	NUM
fnp-3025	555	3	]	]	PUNCT
fnp-3025	555	4	.	.	PUNCT
fnp-3025	556	1	interestingly	interestingly	ADV
fnp-3025	556	2	,	,	PUNCT
fnp-3025	556	3	tauopathy	tauopathy	NOUN
fnp-3025	556	4	was	be	AUX
fnp-3025	556	5	not	not	PART
fnp-3025	556	6	apparent	apparent	ADJ
fnp-3025	556	7	in	in	ADP
fnp-3025	556	8	most	most	ADJ
fnp-3025	556	9	of	of	ADP
fnp-3025	556	10	these	these	DET
fnp-3025	556	11	cases	case	NOUN
fnp-3025	556	12	(	(	PUNCT
fnp-3025	556	13	even	even	ADV
fnp-3025	556	14	though	though	SCONJ
fnp-3025	556	15	some	some	DET
fnp-3025	556	16	abnormal	abnormal	ADJ
fnp-3025	556	17	tau	tau	PROPN
fnp-3025	556	18	is	be	AUX
fnp-3025	556	19	present	present	ADJ
fnp-3025	556	20	in	in	ADP
fnp-3025	556	21	alzheimeric	alzheimeric	ADJ
fnp-3025	556	22	pituitaries	pituitary	NOUN
fnp-3025	556	23	)	)	PUNCT
fnp-3025	556	24	,	,	PUNCT
fnp-3025	556	25	and	and	CCONJ
fnp-3025	556	26	no	no	DET
fnp-3025	556	27	recipients	recipient	NOUN
fnp-3025	556	28	of	of	ADP
fnp-3025	556	29	cadaveric	cadaveric	ADJ
fnp-3025	556	30	growth	growth	NOUN
fnp-3025	556	31	hormone	hormone	NOUN
fnp-3025	556	32	or	or	CCONJ
fnp-3025	556	33	dura	dura	NOUN
fnp-3025	556	34	mater	mater	NOUN
fnp-3025	556	35	have	have	AUX
fnp-3025	556	36	yet	yet	ADV
fnp-3025	556	37	been	be	AUX
fnp-3025	556	38	found	find	VERB
fnp-3025	556	39	to	to	PART
fnp-3025	556	40	develop	develop	VERB
fnp-3025	556	41	full	full	ADV
fnp-3025	556	42	-	-	PUNCT
fnp-3025	556	43	blown	blow	VERB
fnp-3025	556	44	ad	ad	NOUN
fnp-3025	556	45	.	.	PUNCT
fnp-3025	557	1	whether	whether	SCONJ
fnp-3025	557	2	this	this	PRON
fnp-3025	557	3	will	will	AUX
fnp-3025	557	4	happen	happen	VERB
fnp-3025	557	5	as	as	SCONJ
fnp-3025	557	6	the	the	DET
fnp-3025	557	7	subjects	subject	NOUN
fnp-3025	557	8	age	age	NOUN
fnp-3025	557	9	further	far	ADV
fnp-3025	557	10	remains	remain	VERB
fnp-3025	557	11	to	to	PART
fnp-3025	557	12	be	be	AUX
fnp-3025	557	13	determined	determine	VERB
fnp-3025	557	14	.	.	PUNCT
fnp-3025	558	1	10	10	NUM
fnp-3025	558	2	.	.	PUNCT
fnp-3025	559	1	aβ	aβ	NOUN
fnp-3025	559	2	plaques	plaque	NOUN
fnp-3025	559	3	in	in	ADP
fnp-3025	559	4	nonhuman	nonhuman	ADJ
fnp-3025	559	5	species	specie	NOUN
fnp-3025	559	6	10.1	10.1	NUM
fnp-3025	559	7	native	native	ADJ
fnp-3025	559	8	aβ	aβ	NOUN
fnp-3025	559	9	plaques	plaque	NOUN
fnp-3025	559	10	naturally	naturally	ADV
fnp-3025	559	11	occurring	occur	VERB
fnp-3025	559	12	aβ	aβ	DET
fnp-3025	559	13	plaques	plaque	NOUN
fnp-3025	559	14	and/or	and/or	CCONJ
fnp-3025	559	15	aβ	aβ	NOUN
fnp-3025	559	16	-	-	PUNCT
fnp-3025	559	17	caa	caa	NOUN
fnp-3025	559	18	have	have	AUX
fnp-3025	559	19	been	be	AUX
fnp-3025	559	20	identified	identify	VERB
fnp-3025	559	21	in	in	ADP
fnp-3025	559	22	aged	aged	ADJ
fnp-3025	559	23	animals	animal	NOUN
fnp-3025	559	24	of	of	ADP
fnp-3025	559	25	many	many	ADJ
fnp-3025	559	26	species	specie	NOUN
fnp-3025	559	27	,	,	PUNCT
fnp-3025	559	28	including	include	VERB
fnp-3025	559	29	such	such	ADJ
fnp-3025	559	30	diverse	diverse	ADJ
fnp-3025	559	31	creatures	creature	NOUN
fnp-3025	559	32	as	as	ADP
fnp-3025	559	33	woodpeckers	woodpecker	NOUN
fnp-3025	559	34	[	[	X
fnp-3025	559	35	428	428	NUM
fnp-3025	559	36	]	]	PUNCT
fnp-3025	559	37	,	,	PUNCT
fnp-3025	559	38	bears	bear	VERB
fnp-3025	559	39	[	[	PUNCT
fnp-3025	559	40	429	429	NUM
fnp-3025	559	41	-	-	SYM
fnp-3025	559	42	431	431	NUM
fnp-3025	559	43	]	]	PUNCT
fnp-3025	559	44	,	,	PUNCT
fnp-3025	559	45	dogs	dog	NOUN
fnp-3025	559	46	[	[	X
fnp-3025	559	47	432	432	NUM
fnp-3025	559	48	-	-	SYM
fnp-3025	559	49	435	435	NUM
fnp-3025	559	50	]	]	PUNCT
fnp-3025	559	51	,	,	PUNCT
fnp-3025	559	52	cats	cat	NOUN
fnp-3025	559	53	[	[	X
fnp-3025	559	54	436	436	NUM
fnp-3025	559	55	]	]	PUNCT
fnp-3025	559	56	,	,	PUNCT
fnp-3025	559	57	camels	camel	NOUN
fnp-3025	559	58	[	[	X
fnp-3025	559	59	437	437	NUM
fnp-3025	559	60	]	]	PUNCT
fnp-3025	559	61	wolverines	wolverine	NOUN
fnp-3025	560	1	[	[	X
fnp-3025	560	2	438	438	NUM
fnp-3025	560	3	]	]	PUNCT
fnp-3025	560	4	,	,	PUNCT
fnp-3025	560	5	and	and	CCONJ
fnp-3025	560	6	all	all	DET
fnp-3025	560	7	species	specie	NOUN
fnp-3025	560	8	of	of	ADP
fnp-3025	560	9	nonhuman	nonhuman	ADJ
fnp-3025	560	10	primate	primate	NOUN
fnp-3025	560	11	examined	examine	VERB
fnp-3025	560	12	to	to	ADP
fnp-3025	560	13	date	date	NOUN
fnp-3025	560	14	[	[	X
fnp-3025	560	15	165	165	NUM
fnp-3025	560	16	,	,	PUNCT
fnp-3025	560	17	435	435	NUM
fnp-3025	560	18	,	,	PUNCT
fnp-3025	560	19	439	439	NUM
fnp-3025	560	20	]	]	PUNCT
fnp-3025	560	21	.	.	PUNCT
fnp-3025	561	1	the	the	DET
fnp-3025	561	2	mammalian	mammalian	ADJ
fnp-3025	561	3	mainstays	mainstay	NOUN
fnp-3025	561	4	of	of	ADP
fnp-3025	561	5	experimental	experimental	ADJ
fnp-3025	561	6	biology	biology	NOUN
fnp-3025	561	7	rats	rat	NOUN
fnp-3025	561	8	and	and	CCONJ
fnp-3025	561	9	mice	mouse	NOUN
fnp-3025	561	10	do	do	AUX
fnp-3025	561	11	not	not	PART
fnp-3025	561	12	normally	normally	ADV
fnp-3025	561	13	manifest	manifest	VERB
fnp-3025	561	14	plaques	plaque	NOUN
fnp-3025	561	15	in	in	ADP
fnp-3025	561	16	old	old	ADJ
fnp-3025	561	17	age	age	NOUN
fnp-3025	561	18	,	,	PUNCT
fnp-3025	561	19	possibly	possibly	ADV
fnp-3025	561	20	owing	owe	VERB
fnp-3025	561	21	to	to	ADP
fnp-3025	561	22	3	3	NUM
fnp-3025	561	23	amino	amino	NOUN
fnp-3025	561	24	acid	acid	NOUN
fnp-3025	561	25	differences	difference	NOUN
fnp-3025	561	26	in	in	ADP
fnp-3025	561	27	the	the	DET
fnp-3025	561	28	n	n	CCONJ
fnp-3025	561	29	-	-	PUNCT
fnp-3025	561	30	terminal	terminal	ADJ
fnp-3025	561	31	segment	segment	NOUN
fnp-3025	561	32	of	of	ADP
fnp-3025	561	33	aβ	aβ	PRON
fnp-3025	561	34	that	that	PRON
fnp-3025	561	35	render	render	VERB
fnp-3025	561	36	the	the	DET
fnp-3025	561	37	protein	protein	NOUN
fnp-3025	561	38	less	less	ADV
fnp-3025	561	39	likely	likely	ADJ
fnp-3025	561	40	to	to	PART
fnp-3025	561	41	aggregate	aggregate	VERB
fnp-3025	561	42	[	[	X
fnp-3025	561	43	440	440	NUM
fnp-3025	561	44	,	,	PUNCT
fnp-3025	561	45	441	441	NUM
fnp-3025	561	46	]	]	PUNCT
fnp-3025	561	47	.	.	PUNCT
fnp-3025	562	1	most	most	ADJ
fnp-3025	562	2	research	research	NOUN
fnp-3025	562	3	on	on	ADP
fnp-3025	562	4	native	native	ADJ
fnp-3025	562	5	aβ	aβ	NOUN
fnp-3025	562	6	plaques	plaque	NOUN
fnp-3025	562	7	in	in	ADP
fnp-3025	562	8	nonhuman	nonhuman	ADJ
fnp-3025	562	9	species	specie	NOUN
fnp-3025	562	10	has	have	AUX
fnp-3025	562	11	focused	focus	VERB
fnp-3025	562	12	on	on	ADP
fnp-3025	562	13	primates	primate	NOUN
fnp-3025	562	14	ranging	range	VERB
fnp-3025	562	15	from	from	ADP
fnp-3025	562	16	prosimians	prosimian	NOUN
fnp-3025	562	17	to	to	ADP
fnp-3025	562	18	monkeys	monkey	NOUN
fnp-3025	562	19	and	and	CCONJ
fnp-3025	562	20	apes	ape	NOUN
fnp-3025	562	21	[	[	X
fnp-3025	562	22	439	439	NUM
fnp-3025	562	23	]	]	PUNCT
fnp-3025	562	24	,	,	PUNCT
fnp-3025	562	25	work	work	NOUN
fnp-3025	562	26	that	that	PRON
fnp-3025	562	27	has	have	AUX
fnp-3025	562	28	yielded	yield	VERB
fnp-3025	562	29	insights	insight	NOUN
fnp-3025	562	30	into	into	ADP
fnp-3025	562	31	the	the	DET
fnp-3025	562	32	pathobiology	pathobiology	NOUN
fnp-3025	562	33	of	of	ADP
fnp-3025	562	34	the	the	DET
fnp-3025	562	35	lesions	lesion	NOUN
fnp-3025	562	36	[	[	X
fnp-3025	562	37	178	178	NUM
fnp-3025	562	38	,	,	PUNCT
fnp-3025	562	39	439	439	NUM
fnp-3025	562	40	,	,	PUNCT
fnp-3025	562	41	442	442	NUM
fnp-3025	562	42	-	-	SYM
fnp-3025	562	43	444	444	NUM
fnp-3025	562	44	]	]	PUNCT
fnp-3025	562	45	.	.	PUNCT
fnp-3025	563	1	nonhuman	nonhuman	ADJ
fnp-3025	563	2	primates	primate	NOUN
fnp-3025	563	3	express	express	VERB
fnp-3025	563	4	aβ	aβ	NOUN
fnp-3025	563	5	with	with	ADP
fnp-3025	563	6	the	the	DET
fnp-3025	563	7	same	same	ADJ
fnp-3025	563	8	sequence	sequence	NOUN
fnp-3025	563	9	of	of	ADP
fnp-3025	563	10	amino	amino	ADJ
fnp-3025	563	11	acids	acid	NOUN
fnp-3025	563	12	as	as	ADP
fnp-3025	563	13	in	in	ADP
fnp-3025	563	14	humans	human	NOUN
fnp-3025	563	15	,	,	PUNCT
fnp-3025	563	16	and	and	CCONJ
fnp-3025	563	17	both	both	CCONJ
fnp-3025	563	18	diffuse	diffuse	ADJ
fnp-3025	563	19	and	and	CCONJ
fnp-3025	563	20	dense	dense	ADJ
fnp-3025	563	21	-	-	PUNCT
fnp-3025	563	22	core	core	NOUN
fnp-3025	563	23	aβ	aβ	NOUN
fnp-3025	563	24	plaques	plaque	NOUN
fnp-3025	563	25	can	can	AUX
fnp-3025	563	26	be	be	AUX
fnp-3025	563	27	abundant	abundant	ADJ
fnp-3025	563	28	in	in	ADP
fnp-3025	563	29	aged	aged	ADJ
fnp-3025	563	30	primates	primate	NOUN
fnp-3025	563	31	[	[	X
fnp-3025	563	32	439	439	NUM
fnp-3025	563	33	]	]	PUNCT
fnp-3025	563	34	(	(	PUNCT
fnp-3025	563	35	figure	figure	NOUN
fnp-3025	563	36	22	22	NUM
fnp-3025	563	37	)	)	PUNCT
fnp-3025	563	38	.	.	PUNCT
fnp-3025	564	1	some	some	PRON
fnp-3025	564	2	of	of	ADP
fnp-3025	564	3	the	the	DET
fnp-3025	564	4	plaques	plaque	NOUN
fnp-3025	564	5	include	include	VERB
fnp-3025	564	6	reactive	reactive	ADJ
fnp-3025	564	7	glial	glial	ADJ
fnp-3025	564	8	cells	cell	NOUN
fnp-3025	564	9	and	and	CCONJ
fnp-3025	564	10	dysmorphic	dysmorphic	ADJ
fnp-3025	564	11	neurites	neurite	NOUN
fnp-3025	564	12	[	[	X
fnp-3025	564	13	444	444	NUM
fnp-3025	564	14	]	]	PUNCT
fnp-3025	564	15	.	.	PUNCT
fnp-3025	565	1	mass	mass	ADJ
fnp-3025	565	2	-	-	PUNCT
fnp-3025	565	3	spectrometry	spectrometry	NOUN
fnp-3025	565	4	has	have	AUX
fnp-3025	565	5	shown	show	VERB
fnp-3025	565	6	that	that	SCONJ
fnp-3025	565	7	post	post	ADJ
fnp-3025	565	8	-	-	ADJ
fnp-3025	565	9	translational	translational	ADJ
fnp-3025	565	10	modifications	modification	NOUN
fnp-3025	565	11	of	of	ADP
fnp-3025	565	12	aβ	aβ	NOUN
fnp-3025	565	13	are	be	AUX
fnp-3025	565	14	similar	similar	ADJ
fnp-3025	565	15	in	in	ADP
fnp-3025	565	16	humans	human	NOUN
fnp-3025	565	17	and	and	CCONJ
fnp-3025	565	18	squirrel	squirrel	NOUN
fnp-3025	565	19	monkeys	monkey	NOUN
fnp-3025	565	20	(	(	PUNCT
fnp-3025	565	21	saimiri	saimiri	NOUN
fnp-3025	565	22	sciureus	sciureus	PROPN
fnp-3025	565	23	)	)	PUNCT
fnp-3025	565	24	,	,	PUNCT
fnp-3025	565	25	and	and	CCONJ
fnp-3025	565	26	by	by	ADP
fnp-3025	565	27	elisa	elisa	PROPN
fnp-3025	565	28	,	,	PUNCT
fnp-3025	565	29	the	the	DET
fnp-3025	565	30	amount	amount	NOUN
fnp-3025	565	31	of	of	ADP
fnp-3025	565	32	aβ	aβ	NOUN
fnp-3025	565	33	in	in	ADP
fnp-3025	565	34	the	the	DET
fnp-3025	565	35	nonhuman	nonhuman	ADJ
fnp-3025	565	36	primate	primate	NOUN
fnp-3025	565	37	brain	brain	NOUN
fnp-3025	565	38	sometimes	sometimes	ADV
fnp-3025	565	39	exceeds	exceed	VERB
fnp-3025	565	40	that	that	SCONJ
fnp-3025	565	41	in	in	ADP
fnp-3025	565	42	humans	human	NOUN
fnp-3025	565	43	with	with	ADP
fnp-3025	565	44	ad	ad	NOUN
fnp-3025	565	45	[	[	X
fnp-3025	565	46	163	163	NUM
fnp-3025	565	47	]	]	PUNCT
fnp-3025	565	48	.	.	PUNCT
fnp-3025	566	1	despite	despite	SCONJ
fnp-3025	566	2	the	the	DET
fnp-3025	566	3	presence	presence	NOUN
fnp-3025	566	4	of	of	ADP
fnp-3025	566	5	copious	copious	ADJ
fnp-3025	566	6	aberrant	aberrant	NOUN
fnp-3025	566	7	aβ	aβ	NOUN
fnp-3025	566	8	,	,	PUNCT
fnp-3025	566	9	no	no	DET
fnp-3025	566	10	nonhuman	nonhuman	ADJ
fnp-3025	566	11	species	specie	NOUN
fnp-3025	566	12	has	have	AUX
fnp-3025	566	13	yet	yet	ADV
fnp-3025	566	14	been	be	AUX
fnp-3025	566	15	found	find	VERB
fnp-3025	566	16	to	to	PART
fnp-3025	566	17	exhibit	exhibit	VERB
fnp-3025	566	18	the	the	DET
fnp-3025	566	19	full	full	ADJ
fnp-3025	566	20	clinicopathologic	clinicopathologic	ADJ
fnp-3025	566	21	phenotype	phenotype	NOUN
fnp-3025	566	22	of	of	ADP
fnp-3025	566	23	ad	ad	NOUN
fnp-3025	566	24	as	as	SCONJ
fnp-3025	566	25	it	it	PRON
fnp-3025	566	26	occurs	occur	VERB
fnp-3025	566	27	in	in	ADP
fnp-3025	566	28	humans	human	NOUN
fnp-3025	566	29	[	[	X
fnp-3025	566	30	165	165	NUM
fnp-3025	566	31	]	]	PUNCT
fnp-3025	566	32	.	.	PUNCT
fnp-3025	567	1	specifically	specifically	ADV
fnp-3025	567	2	,	,	PUNCT
fnp-3025	567	3	a	a	DET
fnp-3025	567	4	dementia	dementia	NOUN
fnp-3025	567	5	-	-	PUNCT
fnp-3025	567	6	like	like	ADJ
fnp-3025	567	7	condition	condition	NOUN
fnp-3025	567	8	has	have	AUX
fnp-3025	567	9	not	not	PART
fnp-3025	567	10	yet	yet	ADV
fnp-3025	567	11	been	be	AUX
fnp-3025	567	12	identified	identify	VERB
fnp-3025	567	13	,	,	PUNCT
fnp-3025	567	14	and	and	CCONJ
fnp-3025	567	15	tauopathy	tauopathy	ADJ
fnp-3025	567	16	,	,	PUNCT
fnp-3025	567	17	though	though	SCONJ
fnp-3025	567	18	often	often	ADV
fnp-3025	567	19	present	present	ADJ
fnp-3025	567	20	,	,	PUNCT
fnp-3025	567	21	is	be	AUX
fnp-3025	567	22	generally	generally	ADV
fnp-3025	567	23	mild	mild	ADJ
fnp-3025	567	24	,	,	PUNCT
fnp-3025	567	25	even	even	ADV
fnp-3025	567	26	in	in	ADP
fnp-3025	567	27	the	the	DET
fnp-3025	567	28	presence	presence	NOUN
fnp-3025	567	29	of	of	ADP
fnp-3025	567	30	profuse	profuse	NOUN
fnp-3025	567	31	aβ	aβ	NOUN
fnp-3025	567	32	plaques	plaque	NOUN
fnp-3025	567	33	.	.	PUNCT
fnp-3025	568	1	for	for	ADP
fnp-3025	568	2	unknown	unknown	ADJ
fnp-3025	568	3	reasons	reason	NOUN
fnp-3025	568	4	,	,	PUNCT
fnp-3025	568	5	aβ	aβ	NOUN
fnp-3025	568	6	-	-	PUNCT
fnp-3025	568	7	caa	caa	NOUN
fnp-3025	568	8	,	,	PUNCT
fnp-3025	568	9	especially	especially	ADV
fnp-3025	568	10	capillary	capillary	ADJ
fnp-3025	568	11	aβ	aβ	NOUN
fnp-3025	568	12	-	-	PUNCT
fnp-3025	568	13	caa	caa	NOUN
fnp-3025	568	14	,	,	PUNCT
fnp-3025	568	15	is	be	AUX
fnp-3025	568	16	more	more	ADV
fnp-3025	568	17	commonly	commonly	ADV
fnp-3025	568	18	present	present	ADJ
fnp-3025	568	19	in	in	ADP
fnp-3025	568	20	nonhuman	nonhuman	ADJ
fnp-3025	568	21	primates	primate	NOUN
fnp-3025	568	22	than	than	ADP
fnp-3025	568	23	in	in	ADP
fnp-3025	568	24	humans	human	NOUN
fnp-3025	568	25	[	[	X
fnp-3025	568	26	439	439	NUM
fnp-3025	568	27	,	,	PUNCT
fnp-3025	568	28	445	445	NUM
fnp-3025	568	29	,	,	PUNCT
fnp-3025	568	30	446	446	NUM
fnp-3025	568	31	]	]	PUNCT
fnp-3025	568	32	.	.	PUNCT
fnp-3025	569	1	although	although	SCONJ
fnp-3025	569	2	congophilic	congophilic	ADJ
fnp-3025	569	3	aβ	aβ	DET
fnp-3025	569	4	plaques	plaque	NOUN
fnp-3025	569	5	occur	occur	VERB
fnp-3025	569	6	,	,	PUNCT
fnp-3025	569	7	human	human	NOUN
fnp-3025	569	8	-	-	PUNCT
fnp-3025	569	9	like	like	ADJ
fnp-3025	569	10	classical	classical	ADJ
fnp-3025	569	11	plaques	plaque	NOUN
fnp-3025	569	12	with	with	ADP
fnp-3025	569	13	an	an	DET
fnp-3025	569	14	aβ	aβ	NOUN
fnp-3025	569	15	core	core	NOUN
fnp-3025	569	16	,	,	PUNCT
fnp-3025	569	17	space	space	NOUN
fnp-3025	569	18	,	,	PUNCT
fnp-3025	569	19	and	and	CCONJ
fnp-3025	569	20	outer	outer	ADJ
fnp-3025	569	21	corona	corona	NOUN
fnp-3025	569	22	(	(	PUNCT
fnp-3025	569	23	see	see	VERB
fnp-3025	569	24	figure	figure	NOUN
fnp-3025	569	25	1	1	NUM
fnp-3025	569	26	)	)	PUNCT
fnp-3025	569	27	are	be	AUX
fnp-3025	569	28	rare	rare	ADJ
fnp-3025	569	29	,	,	PUNCT
fnp-3025	569	30	if	if	SCONJ
fnp-3025	569	31	they	they	PRON
fnp-3025	569	32	can	can	AUX
fnp-3025	569	33	be	be	AUX
fnp-3025	569	34	found	find	VERB
fnp-3025	569	35	at	at	ADV
fnp-3025	569	36	all	all	ADV
fnp-3025	569	37	,	,	PUNCT
fnp-3025	569	38	in	in	ADP
fnp-3025	569	39	prosimians	prosimian	NOUN
fnp-3025	569	40	and	and	CCONJ
fnp-3025	569	41	monkeys	monkey	NOUN
fnp-3025	569	42	(	(	PUNCT
fnp-3025	569	43	we	we	PRON
fnp-3025	569	44	can	can	AUX
fnp-3025	569	45	not	not	PART
fnp-3025	569	46	yet	yet	ADV
fnp-3025	569	47	rule	rule	VERB
fnp-3025	569	48	out	out	ADP
fnp-3025	569	49	such	such	ADJ
fnp-3025	569	50	lesions	lesion	NOUN
fnp-3025	569	51	in	in	ADP
fnp-3025	569	52	great	great	ADJ
fnp-3025	569	53	apes	ape	NOUN
fnp-3025	569	54	,	,	PUNCT
fnp-3025	569	55	as	as	SCONJ
fnp-3025	569	56	relatively	relatively	ADV
fnp-3025	569	57	few	few	ADJ
fnp-3025	569	58	have	have	AUX
fnp-3025	569	59	been	be	AUX
fnp-3025	569	60	examined	examine	VERB
fnp-3025	569	61	in	in	ADP
fnp-3025	569	62	advanced	advanced	ADJ
fnp-3025	569	63	old	old	ADJ
fnp-3025	569	64	age	age	NOUN
fnp-3025	569	65	)	)	PUNCT
fnp-3025	569	66	.	.	PUNCT
fnp-3025	570	1	surprisingly	surprisingly	ADV
fnp-3025	570	2	,	,	PUNCT
fnp-3025	570	3	there	there	PRON
fnp-3025	570	4	is	be	VERB
fnp-3025	570	5	little	little	ADJ
fnp-3025	570	6	high	high	ADJ
fnp-3025	570	7	-	-	PUNCT
fnp-3025	570	8	affinity	affinity	NOUN
fnp-3025	570	9	binding	binding	NOUN
fnp-3025	570	10	of	of	ADP
fnp-3025	570	11	the	the	DET
fnp-3025	570	12	aβ	aβ	NOUN
fnp-3025	570	13	-	-	PUNCT
fnp-3025	570	14	amyloid	amyloid	NOUN
fnp-3025	570	15	-	-	PUNCT
fnp-3025	570	16	imaging	image	VERB
fnp-3025	570	17	agent	agent	NOUN
fnp-3025	570	18	pittsburgh	pittsburgh	PROPN
fnp-3025	570	19	compound	compound	PROPN
fnp-3025	570	20	-	-	PUNCT
fnp-3025	570	21	b	b	PROPN
fnp-3025	570	22	(	(	PUNCT
fnp-3025	570	23	pib	pib	NOUN
fnp-3025	570	24	)	)	PUNCT
fnp-3025	570	25	to	to	ADP
fnp-3025	570	26	aβ	aβ	VERB
fnp-3025	570	27	plaques	plaque	NOUN
fnp-3025	570	28	in	in	ADP
fnp-3025	570	29	nonhuman	nonhuman	ADJ
fnp-3025	570	30	primates	primate	NOUN
fnp-3025	570	31	,	,	PUNCT
fnp-3025	570	32	suggesting	suggest	VERB
fnp-3025	570	33	biochemical	biochemical	ADJ
fnp-3025	570	34	and/or	and/or	CCONJ
fnp-3025	570	35	conformational	conformational	ADJ
fnp-3025	570	36	differences	difference	NOUN
fnp-3025	570	37	in	in	ADP
fnp-3025	570	38	the	the	DET
fnp-3025	570	39	protein	protein	NOUN
fnp-3025	570	40	between	between	ADP
fnp-3025	570	41	humans	human	NOUN
fnp-3025	570	42	and	and	CCONJ
fnp-3025	570	43	other	other	ADJ
fnp-3025	570	44	primates	primate	NOUN
fnp-3025	570	45	[	[	X
fnp-3025	570	46	447	447	NUM
fnp-3025	570	47	]	]	PUNCT
fnp-3025	570	48	.	.	PUNCT
fnp-3025	571	1	it	it	PRON
fnp-3025	571	2	is	be	AUX
fnp-3025	571	3	necessary	necessary	ADJ
fnp-3025	571	4	to	to	PART
fnp-3025	571	5	determine	determine	VERB
fnp-3025	571	6	how	how	SCONJ
fnp-3025	571	7	differences	difference	NOUN
fnp-3025	571	8	in	in	ADP
fnp-3025	571	9	lifespan	lifespan	NOUN
fnp-3025	571	10	and	and	CCONJ
fnp-3025	571	11	environmental	environmental	ADJ
fnp-3025	571	12	and	and	CCONJ
fnp-3025	571	13	genetic	genetic	ADJ
fnp-3025	571	14	risk	risk	NOUN
fnp-3025	571	15	factors	factor	NOUN
fnp-3025	571	16	might	might	AUX
fnp-3025	571	17	influence	influence	VERB
fnp-3025	571	18	the	the	DET
fnp-3025	571	19	apparent	apparent	ADJ
fnp-3025	571	20	species	specie	NOUN
fnp-3025	571	21	-	-	PUNCT
fnp-3025	571	22	specificity	specificity	NOUN
fnp-3025	571	23	of	of	ADP
fnp-3025	571	24	ad	ad	NOUN
fnp-3025	571	25	and	and	CCONJ
fnp-3025	571	26	the	the	DET
fnp-3025	571	27	aβ	aβ	NOUN
fnp-3025	571	28	-	-	PUNCT
fnp-3025	571	29	deposition	deposition	NOUN
fnp-3025	571	30	phenotype	phenotype	NOUN
fnp-3025	571	31	.	.	PUNCT
fnp-3025	572	1	however	however	ADV
fnp-3025	572	2	,	,	PUNCT
fnp-3025	572	3	current	current	ADJ
fnp-3025	572	4	evidence	evidence	NOUN
fnp-3025	572	5	suggests	suggest	VERB
fnp-3025	572	6	that	that	SCONJ
fnp-3025	572	7	,	,	PUNCT
fnp-3025	572	8	despite	despite	SCONJ
fnp-3025	572	9	similarities	similarity	NOUN
fnp-3025	572	10	in	in	ADP
fnp-3025	572	11	the	the	DET
fnp-3025	572	12	sequence	sequence	NOUN
fnp-3025	572	13	,	,	PUNCT
fnp-3025	572	14	expression	expression	NOUN
fnp-3025	572	15	,	,	PUNCT
fnp-3025	572	16	modification	modification	NOUN
fnp-3025	572	17	,	,	PUNCT
fnp-3025	572	18	and	and	CCONJ
fnp-3025	572	19	deposition	deposition	NOUN
fnp-3025	572	20	of	of	ADP
fnp-3025	572	21	aβ	aβ	NOUN
fnp-3025	572	22	,	,	PUNCT
fnp-3025	572	23	nonhuman	nonhuman	ADJ
fnp-3025	572	24	primates	primate	NOUN
fnp-3025	572	25	lack	lack	VERB
fnp-3025	572	26	the	the	DET
fnp-3025	572	27	permissive	permissive	ADJ
fnp-3025	572	28	connection	connection	NOUN
fnp-3025	572	29	between	between	ADP
fnp-3025	572	30	aβ	aβ	NOUN
fnp-3025	572	31	-	-	PUNCT
fnp-3025	572	32	proteopathy	proteopathy	ADJ
fnp-3025	572	33	and	and	CCONJ
fnp-3025	572	34	tauopathy	tauopathy	NOUN
fnp-3025	572	35	that	that	PRON
fnp-3025	572	36	is	be	AUX
fnp-3025	572	37	critical	critical	ADJ
fnp-3025	572	38	to	to	ADP
fnp-3025	572	39	the	the	DET
fnp-3025	572	40	occurrence	occurrence	NOUN
fnp-3025	572	41	of	of	ADP
fnp-3025	572	42	ad	ad	NOUN
fnp-3025	572	43	in	in	ADP
fnp-3025	572	44	humans	human	NOUN
fnp-3025	572	45	[	[	X
fnp-3025	572	46	165	165	NUM
fnp-3025	572	47	]	]	PUNCT
fnp-3025	572	48	.	.	PUNCT
fnp-3025	573	1	clarifying	clarify	VERB
fnp-3025	573	2	the	the	DET
fnp-3025	573	3	nature	nature	NOUN
fnp-3025	573	4	of	of	ADP
fnp-3025	573	5	this	this	PRON
fnp-3025	573	6	naturally	naturally	ADV
fnp-3025	573	7	occurring	occur	VERB
fnp-3025	573	8	interruption	interruption	NOUN
fnp-3025	573	9	of	of	ADP
fnp-3025	573	10	the	the	DET
fnp-3025	573	11	aβ	aβ	NOUN
fnp-3025	573	12	cascade	cascade	NOUN
fnp-3025	573	13	in	in	ADP
fnp-3025	573	14	nonhuman	nonhuman	ADJ
fnp-3025	573	15	species	specie	NOUN
fnp-3025	573	16	could	could	AUX
fnp-3025	573	17	reveal	reveal	VERB
fnp-3025	573	18	new	new	ADJ
fnp-3025	573	19	pathogenic	pathogenic	ADJ
fnp-3025	573	20	pathways	pathway	NOUN
fnp-3025	573	21	for	for	ADP
fnp-3025	573	22	therapeutic	therapeutic	ADJ
fnp-3025	573	23	intervention	intervention	NOUN
fnp-3025	573	24	in	in	ADP
fnp-3025	573	25	ad	ad	NOUN
fnp-3025	573	26	.	.	PUNCT
fnp-3025	574	1	figure	figure	NOUN
fnp-3025	574	2	22	22	NUM
fnp-3025	574	3	.	.	PUNCT
fnp-3025	575	1	aβ	aβ	PRON
fnp-3025	575	2	deposition	deposition	NOUN
fnp-3025	575	3	(	(	PUNCT
fnp-3025	575	4	left	leave	VERB
fnp-3025	575	5	)	)	PUNCT
fnp-3025	575	6	in	in	ADP
fnp-3025	575	7	the	the	DET
fnp-3025	575	8	superior	superior	ADJ
fnp-3025	575	9	temporal	temporal	ADJ
fnp-3025	575	10	gyrus	gyrus	NOUN
fnp-3025	575	11	and	and	CCONJ
fnp-3025	575	12	a	a	DET
fnp-3025	575	13	neuritic	neuritic	ADJ
fnp-3025	575	14	plaque	plaque	NOUN
fnp-3025	575	15	(	(	PUNCT
fnp-3025	575	16	right	right	ADJ
fnp-3025	575	17	)	)	PUNCT
fnp-3025	575	18	in	in	ADP
fnp-3025	575	19	the	the	DET
fnp-3025	575	20	hippocampal	hippocampal	ADJ
fnp-3025	575	21	formation	formation	NOUN
fnp-3025	575	22	of	of	ADP
fnp-3025	575	23	two	two	NUM
fnp-3025	575	24	aged	aged	ADJ
fnp-3025	575	25	rhesus	rhesus	NOUN
fnp-3025	575	26	monkeys	monkey	NOUN
fnp-3025	575	27	(	(	PUNCT
fnp-3025	575	28	macaca	macaca	NOUN
fnp-3025	575	29	mulatta	mulatta	PROPN
fnp-3025	575	30	;	;	PUNCT
fnp-3025	575	31	35	35	NUM
fnp-3025	575	32	years	year	NOUN
fnp-3025	575	33	and	and	CCONJ
fnp-3025	575	34	~30	~30	NUM
fnp-3025	575	35	years	year	NOUN
fnp-3025	575	36	,	,	PUNCT
fnp-3025	575	37	respectively	respectively	ADV
fnp-3025	575	38	)	)	PUNCT
fnp-3025	575	39	.	.	PUNCT
fnp-3025	576	1	left	leave	VERB
fnp-3025	576	2	:	:	PUNCT
fnp-3025	576	3	antibody	antibody	NOUN
fnp-3025	576	4	82e1	82e1	NUM
fnp-3025	576	5	to	to	ADP
fnp-3025	576	6	the	the	DET
fnp-3025	576	7	n	n	CCONJ
fnp-3025	576	8	-	-	PUNCT
fnp-3025	576	9	terminal	terminal	ADJ
fnp-3025	576	10	segment	segment	NOUN
fnp-3025	576	11	of	of	ADP
fnp-3025	576	12	aβ	aβ	NOUN
fnp-3025	576	13	,	,	PUNCT
fnp-3025	576	14	nissl	nissl	ADJ
fnp-3025	576	15	counterstain	counterstain	NOUN
fnp-3025	576	16	;	;	PUNCT
fnp-3025	576	17	right	right	ADJ
fnp-3025	576	18	:	:	PUNCT
fnp-3025	576	19	antibody	antibody	NOUN
fnp-3025	576	20	06	06	NUM
fnp-3025	576	21	-	-	SYM
fnp-3025	576	22	17	17	NUM
fnp-3025	576	23	to	to	ADP
fnp-3025	576	24	phosphorylated	phosphorylate	VERB
fnp-3025	576	25	neurofilaments	neurofilament	NOUN
fnp-3025	576	26	.	.	PUNCT
fnp-3025	577	1	bars	bar	NOUN
fnp-3025	577	2	=	=	SYM
fnp-3025	577	3	200μm	200μm	NOUN
fnp-3025	577	4	(	(	PUNCT
fnp-3025	577	5	left	leave	VERB
fnp-3025	577	6	)	)	PUNCT
fnp-3025	577	7	and	and	CCONJ
fnp-3025	577	8	25μm	25μm	NUM
fnp-3025	577	9	(	(	PUNCT
fnp-3025	577	10	right	right	NOUN
fnp-3025	577	11	)	)	PUNCT
fnp-3025	577	12	.	.	PUNCT
fnp-3025	578	1	the	the	DET
fnp-3025	578	2	maximum	maximum	ADV
fnp-3025	578	3	known	know	VERB
fnp-3025	578	4	lifespan	lifespan	NOUN
fnp-3025	578	5	of	of	ADP
fnp-3025	578	6	rhesus	rhesus	NOUN
fnp-3025	578	7	monkeys	monkey	NOUN
fnp-3025	578	8	is	be	AUX
fnp-3025	578	9	44	44	NUM
fnp-3025	578	10	years	year	NOUN
fnp-3025	578	11	(	(	PUNCT
fnp-3025	578	12	see	see	VERB
fnp-3025	578	13	stonebarger	stonebarger	NOUN
fnp-3025	578	14	et	et	PROPN
fnp-3025	578	15	al	al	PROPN
fnp-3025	578	16	.	.	PUNCT
fnp-3025	579	1	[	[	X
fnp-3025	579	2	2020	2020	NUM
fnp-3025	579	3	]	]	X
fnp-3025	580	1	[	[	X
fnp-3025	580	2	reference	reference	NOUN
fnp-3025	580	3	512	512	NUM
fnp-3025	580	4	]	]	PUNCT
fnp-3025	580	5	)	)	PUNCT
fnp-3025	580	6	.	.	PUNCT
fnp-3025	581	1	figure	figure	VERB
fnp-3025	581	2	23	23	NUM
fnp-3025	581	3	.	.	PUNCT
fnp-3025	582	1	aβ	aβ	PRON
fnp-3025	582	2	plaques	plaque	NOUN
fnp-3025	582	3	in	in	ADP
fnp-3025	582	4	an	an	DET
fnp-3025	582	5	aged	aged	ADJ
fnp-3025	582	6	(	(	PUNCT
fnp-3025	582	7	28	28	NUM
fnp-3025	582	8	months	month	NOUN
fnp-3025	582	9	)	)	PUNCT
fnp-3025	582	10	tg2576	tg2576	PROPN
fnp-3025	582	11	app	app	ADJ
fnp-3025	582	12	-	-	PUNCT
fnp-3025	582	13	transgenic	transgenic	NOUN
fnp-3025	582	14	mouse	mouse	NOUN
fnp-3025	582	15	.	.	PUNCT
fnp-3025	583	1	diffuse	diffuse	ADJ
fnp-3025	583	2	deposits	deposit	NOUN
fnp-3025	583	3	are	be	AUX
fnp-3025	583	4	black	black	ADJ
fnp-3025	583	5	,	,	PUNCT
fnp-3025	583	6	and	and	CCONJ
fnp-3025	583	7	some	some	DET
fnp-3025	583	8	dense	dense	ADJ
fnp-3025	583	9	deposits	deposit	NOUN
fnp-3025	583	10	have	have	VERB
fnp-3025	583	11	a	a	DET
fnp-3025	583	12	golden	golden	ADJ
fnp-3025	583	13	core	core	NOUN
fnp-3025	583	14	(	(	PUNCT
fnp-3025	583	15	one	one	NUM
fnp-3025	583	16	in	in	ADP
fnp-3025	583	17	the	the	DET
fnp-3025	583	18	frontal	frontal	ADJ
fnp-3025	583	19	cortex	cortex	NOUN
fnp-3025	583	20	is	be	AUX
fnp-3025	583	21	magnified	magnify	VERB
fnp-3025	583	22	at	at	ADP
fnp-3025	583	23	right	right	NOUN
fnp-3025	583	24	)	)	PUNCT
fnp-3025	583	25	.	.	PUNCT
fnp-3025	584	1	campbell	campbell	PROPN
fnp-3025	584	2	-	-	PUNCT
fnp-3025	584	3	gallyas	gallyas	PROPN
fnp-3025	584	4	silver	silver	NOUN
fnp-3025	584	5	stain	stain	NOUN
fnp-3025	584	6	.	.	PUNCT
fnp-3025	585	1	bars	bar	NOUN
fnp-3025	585	2	=	=	PUNCT
fnp-3025	586	1	1	1	NUM
fnp-3025	586	2	mm	mm	NOUN
fnp-3025	586	3	(	(	PUNCT
fnp-3025	586	4	left	left	ADJ
fnp-3025	586	5	)	)	PUNCT
fnp-3025	586	6	and	and	CCONJ
fnp-3025	586	7	50μm	50μm	NOUN
fnp-3025	586	8	(	(	PUNCT
fnp-3025	586	9	right	right	NOUN
fnp-3025	586	10	)	)	PUNCT
fnp-3025	586	11	.	.	PUNCT
fnp-3025	587	1	10.2	10.2	NUM
fnp-3025	588	1	aβ	aβ	NOUN
fnp-3025	588	2	plaques	plaque	NOUN
fnp-3025	588	3	in	in	ADP
fnp-3025	588	4	genetically	genetically	ADV
fnp-3025	588	5	modified	modify	VERB
fnp-3025	588	6	animals	animal	NOUN
fnp-3025	588	7	studies	study	NOUN
fnp-3025	588	8	of	of	ADP
fnp-3025	588	9	naturally	naturally	ADV
fnp-3025	588	10	occurring	occur	VERB
fnp-3025	588	11	plaques	plaque	NOUN
fnp-3025	588	12	in	in	ADP
fnp-3025	588	13	various	various	ADJ
fnp-3025	588	14	species	specie	NOUN
fnp-3025	588	15	have	have	AUX
fnp-3025	588	16	shed	shed	VERB
fnp-3025	588	17	some	some	DET
fnp-3025	588	18	light	light	NOUN
fnp-3025	588	19	on	on	ADP
fnp-3025	588	20	the	the	DET
fnp-3025	588	21	lesions	lesion	NOUN
fnp-3025	588	22	,	,	PUNCT
fnp-3025	588	23	but	but	CCONJ
fnp-3025	588	24	there	there	PRON
fnp-3025	588	25	was	be	VERB
fnp-3025	588	26	no	no	DET
fnp-3025	588	27	practical	practical	ADJ
fnp-3025	588	28	model	model	NOUN
fnp-3025	588	29	in	in	ADP
fnp-3025	588	30	which	which	PRON
fnp-3025	588	31	plaques	plaque	NOUN
fnp-3025	588	32	could	could	AUX
fnp-3025	588	33	be	be	AUX
fnp-3025	588	34	experimentally	experimentally	ADV
fnp-3025	588	35	investigated	investigate	VERB
fnp-3025	588	36	until	until	ADP
fnp-3025	588	37	the	the	DET
fnp-3025	588	38	mid-1990s	mid-1990	NOUN
fnp-3025	588	39	.	.	PUNCT
fnp-3025	589	1	then	then	ADV
fnp-3025	589	2	,	,	PUNCT
fnp-3025	589	3	transgenic	transgenic	NOUN
fnp-3025	589	4	mice	mouse	NOUN
fnp-3025	589	5	were	be	AUX
fnp-3025	589	6	introduced	introduce	VERB
fnp-3025	589	7	that	that	SCONJ
fnp-3025	589	8	overexpress	overexpress	NOUN
fnp-3025	589	9	human	human	ADJ
fnp-3025	589	10	app	app	PROPN
fnp-3025	589	11	with	with	ADP
fnp-3025	589	12	genetic	genetic	ADJ
fnp-3025	589	13	mutations	mutation	NOUN
fnp-3025	589	14	linked	link	VERB
fnp-3025	589	15	to	to	ADP
fnp-3025	589	16	ad	ad	NOUN
fnp-3025	589	17	[	[	X
fnp-3025	589	18	448	448	NUM
fnp-3025	589	19	-	-	SYM
fnp-3025	589	20	450	450	NUM
fnp-3025	589	21	]	]	PUNCT
fnp-3025	589	22	.	.	PUNCT
fnp-3025	590	1	with	with	ADP
fnp-3025	590	2	age	age	NOUN
fnp-3025	590	3	,	,	PUNCT
fnp-3025	590	4	these	these	DET
fnp-3025	590	5	app	app	ADJ
fnp-3025	590	6	-	-	PUNCT
fnp-3025	590	7	transgenic	transgenic	ADJ
fnp-3025	590	8	mice	mouse	NOUN
fnp-3025	590	9	deposit	deposit	NOUN
fnp-3025	590	10	copious	copious	ADJ
fnp-3025	590	11	aβ	aβ	NOUN
fnp-3025	590	12	in	in	ADP
fnp-3025	590	13	the	the	DET
fnp-3025	590	14	brain	brain	NOUN
fnp-3025	590	15	(	(	PUNCT
fnp-3025	590	16	figure	figure	NOUN
fnp-3025	590	17	23	23	NUM
fnp-3025	590	18	)	)	PUNCT
fnp-3025	590	19	.	.	PUNCT
fnp-3025	591	1	they	they	PRON
fnp-3025	591	2	were	be	AUX
fnp-3025	591	3	followed	follow	VERB
fnp-3025	591	4	by	by	ADP
fnp-3025	591	5	a	a	DET
fnp-3025	591	6	wealth	wealth	NOUN
fnp-3025	591	7	of	of	ADP
fnp-3025	591	8	additional	additional	ADJ
fnp-3025	591	9	models	model	NOUN
fnp-3025	591	10	in	in	ADP
fnp-3025	591	11	various	various	ADJ
fnp-3025	591	12	mouse	mouse	NOUN
fnp-3025	591	13	(	(	PUNCT
fnp-3025	591	14	and	and	CCONJ
fnp-3025	591	15	later	later	ADV
fnp-3025	591	16	rat	rat	NOUN
fnp-3025	591	17	)	)	PUNCT
fnp-3025	591	18	strains	strain	VERB
fnp-3025	591	19	with	with	ADP
fnp-3025	591	20	diverse	diverse	ADJ
fnp-3025	591	21	genetic	genetic	ADJ
fnp-3025	591	22	alterations	alteration	NOUN
fnp-3025	591	23	,	,	PUNCT
fnp-3025	591	24	transgene	transgene	ADJ
fnp-3025	591	25	expression	expression	NOUN
fnp-3025	591	26	levels	level	NOUN
fnp-3025	591	27	,	,	PUNCT
fnp-3025	591	28	and	and	CCONJ
fnp-3025	591	29	the	the	DET
fnp-3025	591	30	expression	expression	NOUN
fnp-3025	591	31	or	or	CCONJ
fnp-3025	591	32	deletion	deletion	NOUN
fnp-3025	591	33	of	of	ADP
fnp-3025	591	34	interacting	interact	VERB
fnp-3025	591	35	molecules	molecule	NOUN
fnp-3025	592	1	[	[	X
fnp-3025	592	2	451	451	NUM
fnp-3025	592	3	-	-	SYM
fnp-3025	592	4	453	453	NUM
fnp-3025	592	5	]	]	PUNCT
fnp-3025	592	6	;	;	PUNCT
fnp-3025	592	7	see	see	VERB
fnp-3025	592	8	alzforum	alzforum	NOUN
fnp-3025	592	9	for	for	ADP
fnp-3025	592	10	a	a	DET
fnp-3025	592	11	list	list	NOUN
fnp-3025	592	12	of	of	ADP
fnp-3025	592	13	rodent	rodent	ADJ
fnp-3025	592	14	models	model	NOUN
fnp-3025	592	15	of	of	ADP
fnp-3025	592	16	ad	ad	NOUN
fnp-3025	592	17	-	-	PUNCT
fnp-3025	592	18	like	like	ADJ
fnp-3025	592	19	pathology	pathology	NOUN
fnp-3025	592	20	:	:	PUNCT
fnp-3025	592	21	https://www.alzforum.org/research-models/alzheimers-disease	https://www.alzforum.org/research-models/alzheimers-disease	NOUN
fnp-3025	592	22	)	)	PUNCT
fnp-3025	592	23	.	.	PUNCT
fnp-3025	593	1	not	not	PART
fnp-3025	593	2	surprisingly	surprisingly	ADV
fnp-3025	593	3	,	,	PUNCT
fnp-3025	593	4	the	the	DET
fnp-3025	593	5	sundry	sundry	ADJ
fnp-3025	593	6	genetically	genetically	ADV
fnp-3025	593	7	modified	modify	VERB
fnp-3025	593	8	animals	animal	NOUN
fnp-3025	593	9	exhibit	exhibit	VERB
fnp-3025	593	10	many	many	ADJ
fnp-3025	593	11	plaque	plaque	NOUN
fnp-3025	593	12	(	(	PUNCT
fnp-3025	593	13	and	and	CCONJ
fnp-3025	593	14	caa	caa	NOUN
fnp-3025	593	15	)	)	PUNCT
fnp-3025	593	16	phenotypes	phenotype	NOUN
fnp-3025	593	17	.	.	PUNCT
fnp-3025	594	1	no	no	DET
fnp-3025	594	2	genetically	genetically	ADV
fnp-3025	594	3	modified	modify	VERB
fnp-3025	594	4	rodent	rodent	NOUN
fnp-3025	594	5	,	,	PUNCT
fnp-3025	594	6	including	include	VERB
fnp-3025	594	7	those	those	PRON
fnp-3025	594	8	with	with	ADP
fnp-3025	594	9	multiple	multiple	ADJ
fnp-3025	594	10	modifications	modification	NOUN
fnp-3025	594	11	,	,	PUNCT
fnp-3025	594	12	has	have	AUX
fnp-3025	594	13	manifested	manifest	VERB
fnp-3025	594	14	fully	fully	ADV
fnp-3025	594	15	ad	ad	NOUN
fnp-3025	594	16	-	-	PUNCT
fnp-3025	594	17	like	like	ADJ
fnp-3025	594	18	aβ	aβ	NOUN
fnp-3025	594	19	plaques	plaque	NOUN
fnp-3025	594	20	.	.	PUNCT
fnp-3025	595	1	as	as	ADP
fnp-3025	595	2	in	in	ADP
fnp-3025	595	3	nonhuman	nonhuman	ADJ
fnp-3025	595	4	primates	primate	NOUN
fnp-3025	595	5	,	,	PUNCT
fnp-3025	595	6	the	the	DET
fnp-3025	595	7	core	core	NOUN
fnp-3025	595	8	-	-	PUNCT
fnp-3025	595	9	space	space	NOUN
fnp-3025	595	10	-	-	PUNCT
fnp-3025	595	11	corona	corona	NOUN
fnp-3025	595	12	type	type	NOUN
fnp-3025	595	13	of	of	ADP
fnp-3025	595	14	plaque	plaque	NOUN
fnp-3025	595	15	is	be	AUX
fnp-3025	595	16	not	not	PART
fnp-3025	595	17	typical	typical	ADJ
fnp-3025	595	18	of	of	ADP
fnp-3025	595	19	the	the	DET
fnp-3025	595	20	transgenic	transgenic	NOUN
fnp-3025	595	21	rodent	rodent	NOUN
fnp-3025	595	22	models	model	NOUN
fnp-3025	595	23	.	.	PUNCT
fnp-3025	596	1	the	the	DET
fnp-3025	596	2	plaques	plaque	NOUN
fnp-3025	596	3	do	do	AUX
fnp-3025	596	4	,	,	PUNCT
fnp-3025	596	5	however	however	ADV
fnp-3025	596	6	,	,	PUNCT
fnp-3025	596	7	share	share	VERB
fnp-3025	596	8	several	several	ADJ
fnp-3025	596	9	key	key	ADJ
fnp-3025	596	10	features	feature	NOUN
fnp-3025	596	11	with	with	ADP
fnp-3025	596	12	those	those	PRON
fnp-3025	596	13	in	in	ADP
fnp-3025	596	14	humans	human	NOUN
fnp-3025	596	15	;	;	PUNCT
fnp-3025	596	16	they	they	PRON
fnp-3025	596	17	exhibit	exhibit	VERB
fnp-3025	596	18	a	a	DET
fnp-3025	596	19	range	range	NOUN
fnp-3025	596	20	of	of	ADP
fnp-3025	596	21	morphologies	morphology	NOUN
fnp-3025	596	22	,	,	PUNCT
fnp-3025	596	23	many	many	ADJ
fnp-3025	596	24	have	have	AUX
fnp-3025	596	25	bona	bona	X
fnp-3025	596	26	fide	fide	VERB
fnp-3025	596	27	amyloid	amyloid	NOUN
fnp-3025	596	28	cores	core	NOUN
fnp-3025	596	29	,	,	PUNCT
fnp-3025	596	30	and	and	CCONJ
fnp-3025	596	31	they	they	PRON
fnp-3025	596	32	are	be	AUX
fnp-3025	596	33	invested	invest	VERB
fnp-3025	596	34	by	by	ADP
fnp-3025	596	35	aberrant	aberrant	ADJ
fnp-3025	596	36	neurites	neurite	NOUN
fnp-3025	596	37	and	and	CCONJ
fnp-3025	596	38	glial	glial	ADJ
fnp-3025	596	39	cells	cell	NOUN
fnp-3025	596	40	[	[	X
fnp-3025	596	41	452	452	NUM
fnp-3025	596	42	]	]	PUNCT
fnp-3025	596	43	.	.	PUNCT
fnp-3025	597	1	tau	tau	PROPN
fnp-3025	597	2	abnormalities	abnormality	NOUN
fnp-3025	597	3	occur	occur	VERB
fnp-3025	597	4	,	,	PUNCT
fnp-3025	597	5	but	but	CCONJ
fnp-3025	597	6	human	human	ADJ
fnp-3025	597	7	-	-	PUNCT
fnp-3025	597	8	like	like	ADJ
fnp-3025	597	9	neurofibrillary	neurofibrillary	ADJ
fnp-3025	597	10	tangles	tangle	NOUN
fnp-3025	597	11	have	have	AUX
fnp-3025	597	12	not	not	PART
fnp-3025	597	13	yet	yet	ADV
fnp-3025	597	14	been	be	AUX
fnp-3025	597	15	generated	generate	VERB
fnp-3025	597	16	in	in	ADP
fnp-3025	597	17	rodents	rodent	NOUN
fnp-3025	597	18	.	.	PUNCT
fnp-3025	598	1	nonvertebrate	nonvertebrate	VERB
fnp-3025	598	2	transgenic	transgenic	NOUN
fnp-3025	598	3	animals	animal	NOUN
fnp-3025	598	4	such	such	ADJ
fnp-3025	598	5	as	as	ADP
fnp-3025	598	6	fruit	fruit	NOUN
fnp-3025	598	7	flies	fly	NOUN
fnp-3025	598	8	(	(	PUNCT
fnp-3025	598	9	drosophila	drosophila	NOUN
fnp-3025	598	10	melanogaster	melanogaster	NOUN
fnp-3025	598	11	)	)	PUNCT
fnp-3025	599	1	[	[	X
fnp-3025	599	2	454	454	NUM
fnp-3025	599	3	-	-	SYM
fnp-3025	599	4	456	456	NUM
fnp-3025	599	5	]	]	PUNCT
fnp-3025	599	6	and	and	CCONJ
fnp-3025	599	7	roundworms	roundworm	NOUN
fnp-3025	599	8	(	(	PUNCT
fnp-3025	599	9	caenorhabditis	caenorhabditis	NOUN
fnp-3025	599	10	elegans	elegans	PROPN
fnp-3025	599	11	)	)	PUNCT
fnp-3025	600	1	[	[	X
fnp-3025	600	2	457	457	NUM
fnp-3025	600	3	,	,	PUNCT
fnp-3025	600	4	458	458	NUM
fnp-3025	600	5	]	]	PUNCT
fnp-3025	600	6	have	have	AUX
fnp-3025	600	7	been	be	AUX
fnp-3025	600	8	developed	develop	VERB
fnp-3025	600	9	to	to	PART
fnp-3025	600	10	study	study	VERB
fnp-3025	600	11	the	the	DET
fnp-3025	600	12	pathobiology	pathobiology	NOUN
fnp-3025	600	13	of	of	ADP
fnp-3025	600	14	aβ	aβ	NOUN
fnp-3025	600	15	.	.	PUNCT
fnp-3025	601	1	these	these	DET
fnp-3025	601	2	models	model	NOUN
fnp-3025	601	3	can	can	AUX
fnp-3025	601	4	be	be	AUX
fnp-3025	601	5	useful	useful	ADJ
fnp-3025	601	6	for	for	ADP
fnp-3025	601	7	analyzing	analyze	VERB
fnp-3025	601	8	molecular	molecular	ADJ
fnp-3025	601	9	mechanisms	mechanism	NOUN
fnp-3025	601	10	and	and	CCONJ
fnp-3025	601	11	for	for	ADP
fnp-3025	601	12	studying	study	VERB
fnp-3025	601	13	the	the	DET
fnp-3025	601	14	early	early	ADJ
fnp-3025	601	15	-	-	PUNCT
fnp-3025	601	16	stage	stage	NOUN
fnp-3025	601	17	efficacy	efficacy	NOUN
fnp-3025	601	18	and	and	CCONJ
fnp-3025	601	19	toxicity	toxicity	NOUN
fnp-3025	601	20	of	of	ADP
fnp-3025	601	21	investigational	investigational	ADJ
fnp-3025	601	22	agents	agent	NOUN
fnp-3025	601	23	,	,	PUNCT
fnp-3025	601	24	but	but	CCONJ
fnp-3025	601	25	no	no	DET
fnp-3025	601	26	nonvertebrate	nonvertebrate	NOUN
fnp-3025	601	27	model	model	NOUN
fnp-3025	601	28	has	have	AUX
fnp-3025	601	29	yet	yet	ADV
fnp-3025	601	30	generated	generate	VERB
fnp-3025	601	31	aβ	aβ	ADP
fnp-3025	601	32	plaques	plaque	NOUN
fnp-3025	601	33	that	that	PRON
fnp-3025	601	34	remotely	remotely	ADV
fnp-3025	601	35	resemble	resemble	VERB
fnp-3025	601	36	those	those	PRON
fnp-3025	601	37	in	in	ADP
fnp-3025	601	38	humans	human	NOUN
fnp-3025	601	39	.	.	PUNCT
fnp-3025	602	1	it	it	PRON
fnp-3025	602	2	is	be	AUX
fnp-3025	602	3	difficult	difficult	ADJ
fnp-3025	602	4	to	to	PART
fnp-3025	602	5	overstate	overstate	VERB
fnp-3025	602	6	the	the	DET
fnp-3025	602	7	impact	impact	NOUN
fnp-3025	602	8	that	that	PRON
fnp-3025	602	9	the	the	DET
fnp-3025	602	10	introduction	introduction	NOUN
fnp-3025	602	11	of	of	ADP
fnp-3025	602	12	genetically	genetically	ADV
fnp-3025	602	13	modified	modify	VERB
fnp-3025	602	14	animals	animal	NOUN
fnp-3025	602	15	has	have	AUX
fnp-3025	602	16	had	have	VERB
fnp-3025	602	17	on	on	ADP
fnp-3025	602	18	the	the	DET
fnp-3025	602	19	course	course	NOUN
fnp-3025	602	20	of	of	ADP
fnp-3025	602	21	research	research	NOUN
fnp-3025	602	22	on	on	ADP
fnp-3025	602	23	the	the	DET
fnp-3025	602	24	mechanisms	mechanism	NOUN
fnp-3025	602	25	underlying	underlie	VERB
fnp-3025	602	26	plaque	plaque	NOUN
fnp-3025	602	27	formation	formation	NOUN
fnp-3025	602	28	and	and	CCONJ
fnp-3025	602	29	ad	ad	NOUN
fnp-3025	602	30	.	.	PUNCT
fnp-3025	603	1	for	for	ADP
fnp-3025	603	2	example	example	NOUN
fnp-3025	603	3	,	,	PUNCT
fnp-3025	603	4	transgenic	transgenic	NOUN
fnp-3025	603	5	rodents	rodent	NOUN
fnp-3025	603	6	were	be	AUX
fnp-3025	603	7	used	use	VERB
fnp-3025	603	8	to	to	PART
fnp-3025	603	9	establish	establish	VERB
fnp-3025	603	10	the	the	DET
fnp-3025	603	11	prion	prion	NOUN
fnp-3025	603	12	paradigm	paradigm	NOUN
fnp-3025	603	13	as	as	ADP
fnp-3025	603	14	the	the	DET
fnp-3025	603	15	pre	pre	ADJ
fnp-3025	603	16	-	-	ADJ
fnp-3025	603	17	eminent	eminent	ADJ
fnp-3025	603	18	theory	theory	NOUN
fnp-3025	603	19	of	of	ADP
fnp-3025	603	20	plaque	plaque	NOUN
fnp-3025	603	21	ontogeny	ontogeny	NOUN
fnp-3025	603	22	and	and	CCONJ
fnp-3025	603	23	spread	spread	VERB
fnp-3025	603	24	[	[	X
fnp-3025	603	25	217	217	NUM
fnp-3025	603	26	,	,	PUNCT
fnp-3025	603	27	218	218	NUM
fnp-3025	603	28	,	,	PUNCT
fnp-3025	603	29	407	407	NUM
fnp-3025	603	30	]	]	PUNCT
fnp-3025	603	31	(	(	PUNCT
fnp-3025	603	32	see	see	VERB
fnp-3025	603	33	section	section	NOUN
fnp-3025	603	34	9	9	NUM
fnp-3025	603	35	)	)	PUNCT
fnp-3025	603	36	,	,	PUNCT
fnp-3025	603	37	they	they	PRON
fnp-3025	603	38	are	be	AUX
fnp-3025	603	39	being	be	AUX
fnp-3025	603	40	used	use	VERB
fnp-3025	603	41	to	to	PART
fnp-3025	603	42	probe	probe	VERB
fnp-3025	603	43	the	the	DET
fnp-3025	603	44	role	role	NOUN
fnp-3025	603	45	of	of	ADP
fnp-3025	603	46	glial	glial	ADJ
fnp-3025	603	47	cells	cell	NOUN
fnp-3025	603	48	and	and	CCONJ
fnp-3025	603	49	neuritic	neuritic	ADJ
fnp-3025	603	50	dystrophy	dystrophy	NOUN
fnp-3025	603	51	in	in	ADP
fnp-3025	603	52	plaque	plaque	NOUN
fnp-3025	603	53	pathophysiology	pathophysiology	NOUN
fnp-3025	603	54	(	(	PUNCT
fnp-3025	603	55	see	see	VERB
fnp-3025	603	56	section	section	NOUN
fnp-3025	603	57	6	6	NUM
fnp-3025	603	58	)	)	PUNCT
fnp-3025	603	59	,	,	PUNCT
fnp-3025	603	60	and	and	CCONJ
fnp-3025	603	61	they	they	PRON
fnp-3025	603	62	are	be	AUX
fnp-3025	603	63	a	a	DET
fnp-3025	603	64	vital	vital	ADJ
fnp-3025	603	65	tool	tool	NOUN
fnp-3025	603	66	in	in	ADP
fnp-3025	603	67	the	the	DET
fnp-3025	603	68	preclinical	preclinical	ADJ
fnp-3025	603	69	testing	testing	NOUN
fnp-3025	603	70	of	of	ADP
fnp-3025	603	71	new	new	ADJ
fnp-3025	603	72	therapeutic	therapeutic	ADJ
fnp-3025	603	73	and	and	CCONJ
fnp-3025	603	74	diagnostic	diagnostic	ADJ
fnp-3025	603	75	strategies	strategy	NOUN
fnp-3025	603	76	[	[	X
fnp-3025	603	77	452	452	NUM
fnp-3025	603	78	,	,	PUNCT
fnp-3025	603	79	459	459	NUM
fnp-3025	603	80	-	-	SYM
fnp-3025	603	81	463	463	NUM
fnp-3025	603	82	]	]	PUNCT
fnp-3025	603	83	.	.	PUNCT
fnp-3025	604	1	for	for	ADP
fnp-3025	604	2	instance	instance	NOUN
fnp-3025	604	3	,	,	PUNCT
fnp-3025	604	4	whereas	whereas	SCONJ
fnp-3025	604	5	the	the	DET
fnp-3025	604	6	first	first	ADJ
fnp-3025	604	7	evidence	evidence	NOUN
fnp-3025	604	8	that	that	SCONJ
fnp-3025	604	9	aβ	aβ	PRON
fnp-3025	604	10	plaques	plaque	NOUN
fnp-3025	604	11	and	and	CCONJ
fnp-3025	604	12	aβ	aβ	NOUN
fnp-3025	604	13	-	-	PUNCT
fnp-3025	604	14	caa	caa	NOUN
fnp-3025	604	15	could	could	AUX
fnp-3025	604	16	be	be	AUX
fnp-3025	604	17	targeted	target	VERB
fnp-3025	604	18	by	by	ADP
fnp-3025	604	19	anti	anti	ADJ
fnp-3025	604	20	-	-	ADJ
fnp-3025	604	21	aβ	aβ	ADJ
fnp-3025	604	22	antibodies	antibody	NOUN
fnp-3025	604	23	in	in	ADP
fnp-3025	604	24	the	the	DET
fnp-3025	604	25	living	live	VERB
fnp-3025	604	26	brain	brain	NOUN
fnp-3025	604	27	came	come	VERB
fnp-3025	604	28	from	from	ADP
fnp-3025	604	29	experiments	experiment	NOUN
fnp-3025	604	30	in	in	ADP
fnp-3025	604	31	nonhuman	nonhuman	ADJ
fnp-3025	604	32	primates	primate	NOUN
fnp-3025	604	33	[	[	X
fnp-3025	604	34	464	464	NUM
fnp-3025	604	35	]	]	X
fnp-3025	604	36	,	,	PUNCT
fnp-3025	604	37	genetically	genetically	ADV
fnp-3025	604	38	modified	modify	VERB
fnp-3025	604	39	mice	mouse	NOUN
fnp-3025	604	40	enabled	enable	VERB
fnp-3025	604	41	the	the	DET
fnp-3025	604	42	development	development	NOUN
fnp-3025	604	43	of	of	ADP
fnp-3025	604	44	aβ	aβ	NOUN
fnp-3025	604	45	-	-	PUNCT
fnp-3025	604	46	immunization	immunization	NOUN
fnp-3025	604	47	as	as	ADP
fnp-3025	604	48	a	a	DET
fnp-3025	604	49	strategy	strategy	NOUN
fnp-3025	604	50	for	for	ADP
fnp-3025	604	51	the	the	DET
fnp-3025	604	52	prevention	prevention	NOUN
fnp-3025	604	53	or	or	CCONJ
fnp-3025	604	54	treatment	treatment	NOUN
fnp-3025	604	55	of	of	ADP
fnp-3025	604	56	ad	ad	NOUN
fnp-3025	604	57	[	[	X
fnp-3025	604	58	465	465	NUM
fnp-3025	604	59	]	]	PUNCT
fnp-3025	604	60	.	.	PUNCT
fnp-3025	605	1	the	the	DET
fnp-3025	605	2	application	application	NOUN
fnp-3025	605	3	of	of	ADP
fnp-3025	605	4	longitudinal	longitudinal	ADJ
fnp-3025	605	5	,	,	PUNCT
fnp-3025	605	6	in	in	ADP
fnp-3025	605	7	vivo	vivo	NOUN
fnp-3025	605	8	-	-	PUNCT
fnp-3025	605	9	imaging	imaging	NOUN
fnp-3025	605	10	studies	study	NOUN
fnp-3025	605	11	in	in	ADP
fnp-3025	605	12	murine	murine	ADJ
fnp-3025	605	13	models	model	NOUN
fnp-3025	605	14	has	have	AUX
fnp-3025	605	15	facilitated	facilitate	VERB
fnp-3025	605	16	unique	unique	ADJ
fnp-3025	605	17	insights	insight	NOUN
fnp-3025	605	18	into	into	ADP
fnp-3025	605	19	the	the	DET
fnp-3025	605	20	dynamics	dynamic	NOUN
fnp-3025	605	21	of	of	ADP
fnp-3025	605	22	aβ	aβ	DET
fnp-3025	605	23	plaques	plaque	NOUN
fnp-3025	605	24	and	and	CCONJ
fnp-3025	605	25	their	their	PRON
fnp-3025	605	26	cellular	cellular	ADJ
fnp-3025	605	27	constituents	constituent	NOUN
fnp-3025	605	28	(	(	PUNCT
fnp-3025	605	29	e.g.	e.g.	ADV
fnp-3025	605	30	,	,	PUNCT
fnp-3025	605	31	[	[	X
fnp-3025	605	32	323	323	NUM
fnp-3025	605	33	,	,	PUNCT
fnp-3025	605	34	324	324	NUM
fnp-3025	605	35	,	,	PUNCT
fnp-3025	605	36	466	466	NUM
fnp-3025	605	37	-	-	SYM
fnp-3025	605	38	469	469	NUM
fnp-3025	605	39	]	]	NUM
fnp-3025	605	40	)	)	PUNCT
fnp-3025	605	41	,	,	PUNCT
fnp-3025	605	42	as	as	ADV
fnp-3025	605	43	well	well	ADV
fnp-3025	605	44	as	as	ADP
fnp-3025	605	45	the	the	DET
fnp-3025	605	46	response	response	NOUN
fnp-3025	605	47	of	of	ADP
fnp-3025	605	48	plaques	plaque	NOUN
fnp-3025	605	49	and	and	CCONJ
fnp-3025	605	50	aβ	aβ	NOUN
fnp-3025	605	51	-	-	PUNCT
fnp-3025	605	52	caa	caa	NOUN
fnp-3025	605	53	to	to	ADP
fnp-3025	605	54	therapeutic	therapeutic	ADJ
fnp-3025	605	55	intervention	intervention	NOUN
fnp-3025	606	1	[	[	X
fnp-3025	606	2	451	451	NUM
fnp-3025	606	3	,	,	PUNCT
fnp-3025	606	4	452	452	NUM
fnp-3025	606	5	,	,	PUNCT
fnp-3025	606	6	470	470	NUM
fnp-3025	606	7	]	]	PUNCT
fnp-3025	606	8	.	.	PUNCT
fnp-3025	607	1	currently	currently	ADV
fnp-3025	607	2	,	,	PUNCT
fnp-3025	607	3	genetically	genetically	ADV
fnp-3025	607	4	modified	modify	VERB
fnp-3025	607	5	nonhuman	nonhuman	ADJ
fnp-3025	607	6	primates	primate	NOUN
fnp-3025	607	7	are	be	AUX
fnp-3025	607	8	being	be	AUX
fnp-3025	607	9	created	create	VERB
fnp-3025	607	10	with	with	ADP
fnp-3025	607	11	the	the	DET
fnp-3025	607	12	hope	hope	NOUN
fnp-3025	607	13	that	that	SCONJ
fnp-3025	607	14	they	they	PRON
fnp-3025	607	15	will	will	AUX
fnp-3025	607	16	more	more	ADV
fnp-3025	607	17	completely	completely	ADV
fnp-3025	607	18	recapitulate	recapitulate	VERB
fnp-3025	607	19	a	a	DET
fnp-3025	607	20	human	human	NOUN
fnp-3025	607	21	-	-	PUNCT
fnp-3025	607	22	like	like	ADJ
fnp-3025	607	23	ad	ad	NOUN
fnp-3025	607	24	phenotype	phenotype	NOUN
fnp-3025	607	25	[	[	X
fnp-3025	607	26	471	471	NUM
fnp-3025	607	27	,	,	PUNCT
fnp-3025	607	28	472	472	NUM
fnp-3025	607	29	]	]	PUNCT
fnp-3025	607	30	,	,	PUNCT
fnp-3025	607	31	but	but	CCONJ
fnp-3025	607	32	no	no	DET
fnp-3025	607	33	histopathologic	histopathologic	NOUN
fnp-3025	607	34	findings	finding	NOUN
fnp-3025	607	35	have	have	AUX
fnp-3025	607	36	yet	yet	ADV
fnp-3025	607	37	been	be	AUX
fnp-3025	607	38	reported	report	VERB
fnp-3025	607	39	.	.	PUNCT
fnp-3025	608	1	despite	despite	SCONJ
fnp-3025	608	2	the	the	DET
fnp-3025	608	3	limitation	limitation	NOUN
fnp-3025	608	4	that	that	PRON
fnp-3025	608	5	genetically	genetically	ADV
fnp-3025	608	6	modified	modify	VERB
fnp-3025	608	7	animals	animal	NOUN
fnp-3025	608	8	do	do	AUX
fnp-3025	608	9	not	not	PART
fnp-3025	608	10	yet	yet	ADV
fnp-3025	608	11	fully	fully	ADV
fnp-3025	608	12	recapitulate	recapitulate	VERB
fnp-3025	608	13	ad	ad	NOUN
fnp-3025	608	14	,	,	PUNCT
fnp-3025	608	15	they	they	PRON
fnp-3025	608	16	will	will	AUX
fnp-3025	608	17	continue	continue	VERB
fnp-3025	608	18	to	to	PART
fnp-3025	608	19	play	play	VERB
fnp-3025	608	20	an	an	DET
fnp-3025	608	21	important	important	ADJ
fnp-3025	608	22	part	part	NOUN
fnp-3025	608	23	in	in	ADP
fnp-3025	608	24	deciphering	decipher	VERB
fnp-3025	608	25	the	the	DET
fnp-3025	608	26	pathobiology	pathobiology	NOUN
fnp-3025	608	27	of	of	ADP
fnp-3025	608	28	aβ	aβ	DET
fnp-3025	608	29	plaques	plaque	NOUN
fnp-3025	608	30	.	.	PUNCT
fnp-3025	609	1	11	11	NUM
fnp-3025	609	2	.	.	PUNCT
fnp-3025	610	1	conclusions	conclusion	NOUN
fnp-3025	610	2	:	:	PUNCT
fnp-3025	610	3	aβ	aβ	NOUN
fnp-3025	610	4	plaques	plaque	NOUN
fnp-3025	610	5	as	as	ADP
fnp-3025	610	6	a	a	DET
fnp-3025	610	7	therapeutic	therapeutic	ADJ
fnp-3025	610	8	objective	objective	NOUN
fnp-3025	610	9	aβ	aβ	NOUN
fnp-3025	610	10	plaques	plaque	NOUN
fnp-3025	610	11	are	be	AUX
fnp-3025	610	12	an	an	DET
fnp-3025	610	13	obligatory	obligatory	ADJ
fnp-3025	610	14	component	component	NOUN
fnp-3025	610	15	of	of	ADP
fnp-3025	610	16	the	the	DET
fnp-3025	610	17	pathobiology	pathobiology	NOUN
fnp-3025	610	18	of	of	ADP
fnp-3025	610	19	ad	ad	NOUN
fnp-3025	610	20	,	,	PUNCT
fnp-3025	610	21	and	and	CCONJ
fnp-3025	610	22	as	as	ADP
fnp-3025	610	23	such	such	ADJ
fnp-3025	610	24	,	,	PUNCT
fnp-3025	610	25	strategies	strategy	NOUN
fnp-3025	610	26	to	to	PART
fnp-3025	610	27	reduce	reduce	VERB
fnp-3025	610	28	or	or	CCONJ
fnp-3025	610	29	neutralize	neutralize	VERB
fnp-3025	610	30	plaques	plaque	NOUN
fnp-3025	610	31	intersect	intersect	ADJ
fnp-3025	610	32	with	with	ADP
fnp-3025	610	33	general	general	ADJ
fnp-3025	610	34	strategies	strategy	NOUN
fnp-3025	610	35	to	to	PART
fnp-3025	610	36	prevent	prevent	VERB
fnp-3025	610	37	or	or	CCONJ
fnp-3025	610	38	treat	treat	VERB
fnp-3025	610	39	ad	ad	NOUN
fnp-3025	610	40	.	.	PUNCT
fnp-3025	611	1	however	however	ADV
fnp-3025	611	2	,	,	PUNCT
fnp-3025	611	3	the	the	DET
fnp-3025	611	4	value	value	NOUN
fnp-3025	611	5	of	of	ADP
fnp-3025	611	6	plaques	plaque	NOUN
fnp-3025	611	7	,	,	PUNCT
fnp-3025	611	8	in	in	ADP
fnp-3025	611	9	and	and	CCONJ
fnp-3025	611	10	of	of	ADP
fnp-3025	611	11	themselves	themselves	PRON
fnp-3025	611	12	,	,	PUNCT
fnp-3025	611	13	as	as	SCONJ
fnp-3025	611	14	therapeutic	therapeutic	ADJ
fnp-3025	611	15	targets	target	NOUN
fnp-3025	611	16	is	be	AUX
fnp-3025	611	17	uncertain	uncertain	ADJ
fnp-3025	611	18	.	.	PUNCT
fnp-3025	612	1	there	there	PRON
fnp-3025	612	2	is	be	VERB
fnp-3025	612	3	little	little	ADJ
fnp-3025	612	4	question	question	NOUN
fnp-3025	612	5	that	that	SCONJ
fnp-3025	612	6	aβ	aβ	DET
fnp-3025	612	7	plaques	plaque	NOUN
fnp-3025	612	8	,	,	PUNCT
fnp-3025	612	9	especially	especially	ADV
fnp-3025	612	10	in	in	ADP
fnp-3025	612	11	their	their	PRON
fnp-3025	612	12	more	more	ADV
fnp-3025	612	13	elaborate	elaborate	ADJ
fnp-3025	612	14	states	state	NOUN
fnp-3025	612	15	,	,	PUNCT
fnp-3025	612	16	are	be	AUX
fnp-3025	612	17	deleterious	deleterious	ADJ
fnp-3025	612	18	to	to	ADP
fnp-3025	612	19	brain	brain	NOUN
fnp-3025	612	20	tissue	tissue	NOUN
fnp-3025	612	21	;	;	PUNCT
fnp-3025	612	22	they	they	PRON
fnp-3025	612	23	disrupt	disrupt	VERB
fnp-3025	612	24	neuronal	neuronal	ADJ
fnp-3025	612	25	processes	process	NOUN
fnp-3025	612	26	and	and	CCONJ
fnp-3025	612	27	synapses	synapsis	NOUN
fnp-3025	612	28	,	,	PUNCT
fnp-3025	612	29	they	they	PRON
fnp-3025	612	30	can	can	AUX
fnp-3025	612	31	be	be	AUX
fnp-3025	612	32	a	a	DET
fnp-3025	612	33	source	source	NOUN
fnp-3025	612	34	of	of	ADP
fnp-3025	612	35	harmful	harmful	ADJ
fnp-3025	612	36	aβ	aβ	NOUN
fnp-3025	612	37	-	-	PUNCT
fnp-3025	612	38	oligomers	oligomer	NOUN
fnp-3025	612	39	,	,	PUNCT
fnp-3025	612	40	and	and	CCONJ
fnp-3025	612	41	local	local	ADJ
fnp-3025	612	42	glial	glial	ADJ
fnp-3025	612	43	cells	cell	NOUN
fnp-3025	612	44	create	create	VERB
fnp-3025	612	45	a	a	DET
fnp-3025	612	46	toxic	toxic	ADJ
fnp-3025	612	47	inflammatory	inflammatory	ADJ
fnp-3025	612	48	environment	environment	NOUN
fnp-3025	612	49	.	.	PUNCT
fnp-3025	613	1	therapeutically	therapeutically	ADV
fnp-3025	613	2	targeting	target	VERB
fnp-3025	613	3	plaques	plaque	NOUN
fnp-3025	613	4	thus	thus	ADV
fnp-3025	613	5	presents	present	VERB
fnp-3025	613	6	both	both	DET
fnp-3025	613	7	opportunity	opportunity	NOUN
fnp-3025	613	8	and	and	CCONJ
fnp-3025	613	9	obstacles	obstacle	NOUN
fnp-3025	613	10	.	.	PUNCT
fnp-3025	614	1	first	first	ADV
fnp-3025	614	2	,	,	PUNCT
fnp-3025	614	3	given	give	VERB
fnp-3025	614	4	the	the	DET
fnp-3025	614	5	long	long	ADJ
fnp-3025	614	6	,	,	PUNCT
fnp-3025	614	7	pre	pre	ADJ
fnp-3025	614	8	-	-	ADJ
fnp-3025	614	9	symptomatic	symptomatic	ADJ
fnp-3025	614	10	emergence	emergence	NOUN
fnp-3025	614	11	and	and	CCONJ
fnp-3025	614	12	proliferation	proliferation	NOUN
fnp-3025	614	13	of	of	ADP
fnp-3025	614	14	aβ	aβ	DET
fnp-3025	614	15	plaques	plaque	NOUN
fnp-3025	614	16	(	(	PUNCT
fnp-3025	614	17	and	and	CCONJ
fnp-3025	614	18	neurofibrillary	neurofibrillary	ADJ
fnp-3025	614	19	tangles	tangle	NOUN
fnp-3025	614	20	)	)	PUNCT
fnp-3025	614	21	in	in	ADP
fnp-3025	614	22	the	the	DET
fnp-3025	614	23	brain	brain	NOUN
fnp-3025	615	1	[	[	X
fnp-3025	615	2	109	109	NUM
fnp-3025	615	3	,	,	PUNCT
fnp-3025	615	4	473	473	NUM
fnp-3025	615	5	]	]	PUNCT
fnp-3025	615	6	,	,	PUNCT
fnp-3025	615	7	as	as	ADV
fnp-3025	615	8	well	well	ADV
fnp-3025	615	9	as	as	ADP
fnp-3025	615	10	evidence	evidence	NOUN
fnp-3025	615	11	of	of	ADP
fnp-3025	615	12	extensive	extensive	ADJ
fnp-3025	615	13	brain	brain	NOUN
fnp-3025	615	14	damage	damage	NOUN
fnp-3025	615	15	by	by	ADP
fnp-3025	615	16	the	the	DET
fnp-3025	615	17	time	time	NOUN
fnp-3025	615	18	dementia	dementia	NOUN
fnp-3025	615	19	sets	set	VERB
fnp-3025	615	20	in	in	ADP
fnp-3025	615	21	,	,	PUNCT
fnp-3025	615	22	early	early	ADJ
fnp-3025	615	23	prevention	prevention	NOUN
fnp-3025	615	24	is	be	AUX
fnp-3025	615	25	likely	likely	ADJ
fnp-3025	615	26	to	to	PART
fnp-3025	615	27	be	be	AUX
fnp-3025	615	28	the	the	DET
fnp-3025	615	29	most	most	ADV
fnp-3025	615	30	effective	effective	ADJ
fnp-3025	615	31	strategy	strategy	NOUN
fnp-3025	615	32	for	for	ADP
fnp-3025	615	33	subduing	subdue	VERB
fnp-3025	615	34	ad	ad	NOUN
fnp-3025	616	1	[	[	X
fnp-3025	616	2	474	474	NUM
fnp-3025	616	3	,	,	PUNCT
fnp-3025	616	4	475	475	NUM
fnp-3025	616	5	]	]	PUNCT
fnp-3025	616	6	.	.	PUNCT
fnp-3025	617	1	the	the	DET
fnp-3025	617	2	promise	promise	NOUN
fnp-3025	617	3	of	of	ADP
fnp-3025	617	4	prevention	prevention	NOUN
fnp-3025	617	5	is	be	AUX
fnp-3025	617	6	underscored	underscore	VERB
fnp-3025	617	7	by	by	ADP
fnp-3025	617	8	the	the	DET
fnp-3025	617	9	protective	protective	ADJ
fnp-3025	617	10	effects	effect	NOUN
fnp-3025	617	11	of	of	ADP
fnp-3025	617	12	the	the	DET
fnp-3025	617	13	a673	a673	PROPN
fnp-3025	617	14	t	t	NOUN
fnp-3025	617	15	mutation	mutation	NOUN
fnp-3025	617	16	in	in	ADP
fnp-3025	617	17	app	app	PROPN
fnp-3025	617	18	,	,	PUNCT
fnp-3025	617	19	which	which	PRON
fnp-3025	617	20	diminishes	diminish	VERB
fnp-3025	617	21	aβ	aβ	PRON
fnp-3025	617	22	production	production	NOUN
fnp-3025	617	23	throughout	throughout	ADP
fnp-3025	617	24	life	life	NOUN
fnp-3025	617	25	and	and	CCONJ
fnp-3025	617	26	lowers	lower	VERB
fnp-3025	617	27	the	the	DET
fnp-3025	617	28	risk	risk	NOUN
fnp-3025	617	29	of	of	ADP
fnp-3025	617	30	ad	ad	NOUN
fnp-3025	617	31	[	[	X
fnp-3025	617	32	48	48	NUM
fnp-3025	617	33	]	]	PUNCT
fnp-3025	617	34	.	.	PUNCT
fnp-3025	618	1	since	since	SCONJ
fnp-3025	618	2	the	the	DET
fnp-3025	618	3	most	most	ADV
fnp-3025	618	4	effective	effective	ADJ
fnp-3025	618	5	preventive	preventive	ADJ
fnp-3025	618	6	protocol	protocol	NOUN
fnp-3025	618	7	should	should	AUX
fnp-3025	618	8	be	be	AUX
fnp-3025	618	9	initiated	initiate	VERB
fnp-3025	618	10	years	year	NOUN
fnp-3025	618	11	,	,	PUNCT
fnp-3025	618	12	and	and	CCONJ
fnp-3025	618	13	possibly	possibly	ADV
fnp-3025	618	14	decades	decade	NOUN
fnp-3025	618	15	,	,	PUNCT
fnp-3025	618	16	before	before	ADP
fnp-3025	618	17	the	the	DET
fnp-3025	618	18	predicted	predict	VERB
fnp-3025	618	19	onset	onset	NOUN
fnp-3025	618	20	of	of	ADP
fnp-3025	618	21	dementia	dementia	NOUN
fnp-3025	618	22	,	,	PUNCT
fnp-3025	618	23	testing	test	VERB
fnp-3025	618	24	for	for	ADP
fnp-3025	618	25	long	long	ADJ
fnp-3025	618	26	-	-	PUNCT
fnp-3025	618	27	term	term	NOUN
fnp-3025	618	28	safety	safety	NOUN
fnp-3025	618	29	and	and	CCONJ
fnp-3025	618	30	efficacy	efficacy	NOUN
fnp-3025	618	31	will	will	AUX
fnp-3025	618	32	be	be	AUX
fnp-3025	618	33	challenging	challenge	VERB
fnp-3025	618	34	.	.	PUNCT
fnp-3025	619	1	additionally	additionally	ADV
fnp-3025	619	2	,	,	PUNCT
fnp-3025	619	3	it	it	PRON
fnp-3025	619	4	is	be	AUX
fnp-3025	619	5	not	not	PART
fnp-3025	619	6	known	know	VERB
fnp-3025	619	7	when	when	SCONJ
fnp-3025	619	8	,	,	PUNCT
fnp-3025	619	9	in	in	ADP
fnp-3025	619	10	the	the	DET
fnp-3025	619	11	course	course	NOUN
fnp-3025	619	12	of	of	ADP
fnp-3025	619	13	life	life	NOUN
fnp-3025	619	14	,	,	PUNCT
fnp-3025	619	15	therapy	therapy	NOUN
fnp-3025	619	16	must	must	AUX
fnp-3025	619	17	begin	begin	VERB
fnp-3025	619	18	to	to	PART
fnp-3025	619	19	effectively	effectively	ADV
fnp-3025	619	20	prevent	prevent	VERB
fnp-3025	619	21	or	or	CCONJ
fnp-3025	619	22	delay	delay	VERB
fnp-3025	619	23	ad	ad	NOUN
fnp-3025	619	24	.	.	PUNCT
fnp-3025	620	1	second	second	ADJ
fnp-3025	620	2	,	,	PUNCT
fnp-3025	620	3	it	it	PRON
fnp-3025	620	4	is	be	AUX
fnp-3025	620	5	possible	possible	ADJ
fnp-3025	620	6	that	that	SCONJ
fnp-3025	620	7	some	some	PRON
fnp-3025	620	8	,	,	PUNCT
fnp-3025	620	9	if	if	SCONJ
fnp-3025	620	10	not	not	PART
fnp-3025	620	11	most	most	ADJ
fnp-3025	620	12	,	,	PUNCT
fnp-3025	620	13	of	of	ADP
fnp-3025	620	14	the	the	DET
fnp-3025	620	15	direct	direct	ADJ
fnp-3025	620	16	toxic	toxic	ADJ
fnp-3025	620	17	influence	influence	NOUN
fnp-3025	620	18	of	of	ADP
fnp-3025	620	19	the	the	DET
fnp-3025	620	20	aβ	aβ	NOUN
fnp-3025	620	21	is	be	AUX
fnp-3025	620	22	mediated	mediate	VERB
fnp-3025	620	23	by	by	ADP
fnp-3025	620	24	oligomeric	oligomeric	ADJ
fnp-3025	620	25	aβ	aβ	NOUN
fnp-3025	620	26	rather	rather	ADV
fnp-3025	620	27	than	than	ADP
fnp-3025	620	28	by	by	ADP
fnp-3025	620	29	fibrillar	fibrillar	ADJ
fnp-3025	620	30	amyloid	amyloid	NOUN
fnp-3025	620	31	per	per	ADP
fnp-3025	620	32	se	se	X
fnp-3025	620	33	.	.	PUNCT
fnp-3025	621	1	evidence	evidence	NOUN
fnp-3025	621	2	that	that	SCONJ
fnp-3025	621	3	aβ	aβ	DET
fnp-3025	621	4	plaques	plaque	NOUN
fnp-3025	621	5	can	can	AUX
fnp-3025	621	6	serve	serve	VERB
fnp-3025	621	7	as	as	ADP
fnp-3025	621	8	a	a	DET
fnp-3025	621	9	source	source	NOUN
fnp-3025	621	10	of	of	ADP
fnp-3025	621	11	oligomers	oligomer	NOUN
fnp-3025	621	12	(	(	PUNCT
fnp-3025	621	13	section	section	NOUN
fnp-3025	621	14	1.1	1.1	NUM
fnp-3025	621	15	)	)	PUNCT
fnp-3025	621	16	argues	argue	VERB
fnp-3025	621	17	that	that	SCONJ
fnp-3025	621	18	some	some	DET
fnp-3025	621	19	benefit	benefit	NOUN
fnp-3025	621	20	can	can	AUX
fnp-3025	621	21	be	be	AUX
fnp-3025	621	22	achieved	achieve	VERB
fnp-3025	621	23	by	by	ADP
fnp-3025	621	24	reducing	reduce	VERB
fnp-3025	621	25	plaque	plaque	NOUN
fnp-3025	621	26	burden	burden	NOUN
fnp-3025	621	27	and	and	CCONJ
fnp-3025	621	28	thus	thus	ADV
fnp-3025	621	29	the	the	DET
fnp-3025	621	30	accompanying	accompanying	ADJ
fnp-3025	621	31	oligomers	oligomer	NOUN
fnp-3025	621	32	.	.	PUNCT
fnp-3025	622	1	it	it	PRON
fnp-3025	622	2	is	be	AUX
fnp-3025	622	3	encouraging	encouraging	ADJ
fnp-3025	622	4	that	that	SCONJ
fnp-3025	622	5	several	several	ADJ
fnp-3025	622	6	of	of	ADP
fnp-3025	622	7	the	the	DET
fnp-3025	622	8	more	more	ADV
fnp-3025	622	9	promising	promising	ADJ
fnp-3025	622	10	antibodies	antibody	NOUN
fnp-3025	622	11	currently	currently	ADV
fnp-3025	622	12	in	in	ADP
fnp-3025	622	13	clinical	clinical	ADJ
fnp-3025	622	14	trials	trial	NOUN
fnp-3025	622	15	for	for	ADP
fnp-3025	622	16	ad	ad	NOUN
fnp-3025	622	17	show	show	NOUN
fnp-3025	622	18	activity	activity	NOUN
fnp-3025	622	19	against	against	ADP
fnp-3025	622	20	oligomeric	oligomeric	ADJ
fnp-3025	622	21	aβ	aβ	NOUN
fnp-3025	623	1	[	[	X
fnp-3025	623	2	475	475	NUM
fnp-3025	623	3	,	,	PUNCT
fnp-3025	623	4	476	476	NUM
fnp-3025	623	5	]	]	PUNCT
fnp-3025	623	6	.	.	PUNCT
fnp-3025	624	1	a	a	DET
fnp-3025	624	2	recent	recent	ADJ
fnp-3025	624	3	study	study	NOUN
fnp-3025	624	4	in	in	ADP
fnp-3025	624	5	mice	mouse	NOUN
fnp-3025	624	6	indicates	indicate	VERB
fnp-3025	624	7	that	that	SCONJ
fnp-3025	624	8	the	the	DET
fnp-3025	624	9	short	short	ADJ
fnp-3025	624	10	-	-	PUNCT
fnp-3025	624	11	term	term	NOUN
fnp-3025	624	12	neutralization	neutralization	NOUN
fnp-3025	624	13	of	of	ADP
fnp-3025	624	14	oligomeric	oligomeric	ADJ
fnp-3025	624	15	aβ	aβ	NOUN
fnp-3025	624	16	seeds	seed	NOUN
fnp-3025	624	17	early	early	ADV
fnp-3025	624	18	in	in	ADP
fnp-3025	624	19	life	life	NOUN
fnp-3025	624	20	diminishes	diminish	VERB
fnp-3025	624	21	plaque	plaque	NOUN
fnp-3025	624	22	formation	formation	NOUN
fnp-3025	624	23	as	as	ADP
fnp-3025	624	24	the	the	DET
fnp-3025	624	25	animals	animal	NOUN
fnp-3025	624	26	age	age	NOUN
fnp-3025	624	27	[	[	X
fnp-3025	624	28	477	477	NUM
fnp-3025	624	29	]	]	PUNCT
fnp-3025	624	30	.	.	PUNCT
fnp-3025	625	1	however	however	ADV
fnp-3025	625	2	,	,	PUNCT
fnp-3025	625	3	whether	whether	SCONJ
fnp-3025	625	4	mitigating	mitigate	VERB
fnp-3025	625	5	the	the	DET
fnp-3025	625	6	production	production	NOUN
fnp-3025	625	7	,	,	PUNCT
fnp-3025	625	8	seeding	seed	VERB
fnp-3025	625	9	potential	potential	NOUN
fnp-3025	625	10	or	or	CCONJ
fnp-3025	625	11	toxicity	toxicity	NOUN
fnp-3025	625	12	of	of	ADP
fnp-3025	625	13	oligomeric	oligomeric	ADJ
fnp-3025	625	14	aβ	aβ	NOUN
fnp-3025	625	15	will	will	AUX
fnp-3025	625	16	be	be	AUX
fnp-3025	625	17	beneficial	beneficial	ADJ
fnp-3025	625	18	in	in	ADP
fnp-3025	625	19	humans	human	NOUN
fnp-3025	625	20	,	,	PUNCT
fnp-3025	625	21	either	either	CCONJ
fnp-3025	625	22	as	as	ADP
fnp-3025	625	23	a	a	DET
fnp-3025	625	24	preventive	preventive	ADJ
fnp-3025	625	25	or	or	CCONJ
fnp-3025	625	26	as	as	ADP
fnp-3025	625	27	a	a	DET
fnp-3025	625	28	treatment	treatment	NOUN
fnp-3025	625	29	for	for	ADP
fnp-3025	625	30	discernible	discernible	ADJ
fnp-3025	625	31	dementia	dementia	NOUN
fnp-3025	625	32	,	,	PUNCT
fnp-3025	625	33	remains	remain	VERB
fnp-3025	625	34	to	to	PART
fnp-3025	625	35	be	be	AUX
fnp-3025	625	36	determined	determine	VERB
fnp-3025	625	37	.	.	PUNCT
fnp-3025	626	1	it	it	PRON
fnp-3025	626	2	is	be	AUX
fnp-3025	626	3	also	also	ADV
fnp-3025	626	4	important	important	ADJ
fnp-3025	626	5	to	to	PART
fnp-3025	626	6	consider	consider	VERB
fnp-3025	626	7	the	the	DET
fnp-3025	626	8	possibility	possibility	NOUN
fnp-3025	626	9	that	that	SCONJ
fnp-3025	626	10	treatments	treatment	VERB
fnp-3025	626	11	that	that	PRON
fnp-3025	626	12	block	block	VERB
fnp-3025	626	13	aβ	aβ	NOUN
fnp-3025	626	14	-	-	PUNCT
fnp-3025	626	15	amyloid	amyloid	NOUN
fnp-3025	626	16	fibril	fibril	ADJ
fnp-3025	626	17	assembly	assembly	NOUN
fnp-3025	626	18	,	,	PUNCT
fnp-3025	626	19	or	or	CCONJ
fnp-3025	626	20	that	that	DET
fnp-3025	626	21	disassemble	disassemble	ADJ
fnp-3025	626	22	plaques	plaque	NOUN
fnp-3025	626	23	,	,	PUNCT
fnp-3025	626	24	might	might	AUX
fnp-3025	626	25	inadvertently	inadvertently	ADV
fnp-3025	626	26	increase	increase	VERB
fnp-3025	626	27	the	the	DET
fnp-3025	626	28	presence	presence	NOUN
fnp-3025	626	29	of	of	ADP
fnp-3025	626	30	toxic	toxic	ADJ
fnp-3025	626	31	oligomers	oligomer	NOUN
fnp-3025	626	32	.	.	PUNCT
fnp-3025	627	1	third	third	ADJ
fnp-3025	627	2	,	,	PUNCT
fnp-3025	627	3	the	the	DET
fnp-3025	627	4	inability	inability	NOUN
fnp-3025	627	5	of	of	ADP
fnp-3025	627	6	anti	anti	ADJ
fnp-3025	627	7	-	-	ADJ
fnp-3025	627	8	aβ	aβ	ADJ
fnp-3025	627	9	immunotherapies	immunotherapy	NOUN
fnp-3025	627	10	to	to	PART
fnp-3025	627	11	substantially	substantially	ADV
fnp-3025	627	12	impede	impede	VERB
fnp-3025	627	13	dementia	dementia	NOUN
fnp-3025	627	14	in	in	ADP
fnp-3025	627	15	symptomatic	symptomatic	ADJ
fnp-3025	627	16	subjects	subject	NOUN
fnp-3025	627	17	,	,	PUNCT
fnp-3025	627	18	even	even	ADV
fnp-3025	627	19	when	when	SCONJ
fnp-3025	627	20	aβ	aβ	PRON
fnp-3025	627	21	plaques	plaque	NOUN
fnp-3025	627	22	are	be	AUX
fnp-3025	627	23	reduced	reduce	VERB
fnp-3025	627	24	in	in	ADP
fnp-3025	627	25	number	number	NOUN
fnp-3025	627	26	[	[	X
fnp-3025	627	27	336	336	NUM
fnp-3025	627	28	,	,	PUNCT
fnp-3025	627	29	476	476	NUM
fnp-3025	627	30	,	,	PUNCT
fnp-3025	627	31	478	478	NUM
fnp-3025	627	32	,	,	PUNCT
fnp-3025	627	33	479	479	NUM
fnp-3025	627	34	]	]	PUNCT
fnp-3025	627	35	,	,	PUNCT
fnp-3025	627	36	suggests	suggest	VERB
fnp-3025	627	37	that	that	SCONJ
fnp-3025	627	38	the	the	DET
fnp-3025	627	39	dis	dis	PROPN
fnp-3025	627	40	-	-	PUNCT
fnp-3025	627	41	integration	integration	NOUN
fnp-3025	627	42	of	of	ADP
fnp-3025	627	43	the	the	DET
fnp-3025	627	44	cerebral	cerebral	ADJ
fnp-3025	627	45	connectome	connectome	PROPN
fnp-3025	627	46	caused	cause	VERB
fnp-3025	627	47	by	by	ADP
fnp-3025	627	48	plaques	plaque	NOUN
fnp-3025	627	49	and	and	CCONJ
fnp-3025	627	50	tangles	tangle	NOUN
fnp-3025	627	51	is	be	AUX
fnp-3025	627	52	pronounced	pronounce	VERB
fnp-3025	627	53	and	and	CCONJ
fnp-3025	627	54	largely	largely	ADV
fnp-3025	627	55	irreversible	irreversible	ADJ
fnp-3025	627	56	once	once	SCONJ
fnp-3025	627	57	dementia	dementia	NOUN
fnp-3025	627	58	commences	commence	VERB
fnp-3025	627	59	[	[	X
fnp-3025	627	60	9	9	NUM
fnp-3025	627	61	,	,	PUNCT
fnp-3025	627	62	474	474	NUM
fnp-3025	627	63	]	]	PUNCT
fnp-3025	627	64	.	.	PUNCT
fnp-3025	628	1	furthermore	furthermore	ADV
fnp-3025	628	2	,	,	PUNCT
fnp-3025	628	3	tauopathy	tauopathy	ADJ
fnp-3025	628	4	is	be	AUX
fnp-3025	628	5	an	an	DET
fnp-3025	628	6	essential	essential	ADJ
fnp-3025	628	7	contributor	contributor	NOUN
fnp-3025	628	8	to	to	PART
fnp-3025	628	9	dementia	dementia	VERB
fnp-3025	628	10	that	that	PRON
fnp-3025	628	11	itself	itself	PRON
fnp-3025	628	12	progresses	progress	VERB
fnp-3025	628	13	by	by	ADP
fnp-3025	628	14	a	a	DET
fnp-3025	628	15	prion	prion	NOUN
fnp-3025	628	16	-	-	PUNCT
fnp-3025	628	17	like	like	ADJ
fnp-3025	628	18	mechanism	mechanism	NOUN
fnp-3025	628	19	[	[	X
fnp-3025	628	20	480	480	NUM
fnp-3025	628	21	,	,	PUNCT
fnp-3025	628	22	481	481	NUM
fnp-3025	628	23	]	]	PUNCT
fnp-3025	628	24	that	that	PRON
fnp-3025	628	25	may	may	AUX
fnp-3025	628	26	be	be	AUX
fnp-3025	628	27	at	at	ADV
fnp-3025	628	28	least	least	ADJ
fnp-3025	628	29	partly	partly	ADV
fnp-3025	628	30	independent	independent	ADJ
fnp-3025	628	31	of	of	ADP
fnp-3025	628	32	aβ	aβ	NOUN
fnp-3025	628	33	-	-	PUNCT
fnp-3025	628	34	proteopathy	proteopathy	ADJ
fnp-3025	628	35	[	[	X
fnp-3025	628	36	336	336	NUM
fnp-3025	628	37	]	]	PUNCT
fnp-3025	628	38	.	.	PUNCT
fnp-3025	629	1	whether	whether	SCONJ
fnp-3025	629	2	the	the	DET
fnp-3025	629	3	alternative	alternative	ADJ
fnp-3025	629	4	approach	approach	NOUN
fnp-3025	629	5	of	of	ADP
fnp-3025	629	6	lowering	lower	VERB
fnp-3025	629	7	the	the	DET
fnp-3025	629	8	inflammatory	inflammatory	ADJ
fnp-3025	629	9	state	state	NOUN
fnp-3025	629	10	associated	associate	VERB
fnp-3025	629	11	with	with	ADP
fnp-3025	629	12	plaques	plaque	NOUN
fnp-3025	629	13	will	will	AUX
fnp-3025	629	14	meaningfully	meaningfully	ADV
fnp-3025	629	15	improve	improve	VERB
fnp-3025	629	16	behavior	behavior	NOUN
fnp-3025	629	17	at	at	ADP
fnp-3025	629	18	this	this	DET
fnp-3025	629	19	later	later	ADJ
fnp-3025	629	20	stage	stage	NOUN
fnp-3025	629	21	of	of	ADP
fnp-3025	629	22	disease	disease	NOUN
fnp-3025	629	23	also	also	ADV
fnp-3025	629	24	has	have	AUX
fnp-3025	629	25	not	not	PART
fnp-3025	629	26	been	be	AUX
fnp-3025	629	27	established	establish	VERB
fnp-3025	629	28	.	.	PUNCT
fnp-3025	630	1	in	in	ADP
fnp-3025	630	2	short	short	ADJ
fnp-3025	630	3	,	,	PUNCT
fnp-3025	630	4	once	once	SCONJ
fnp-3025	630	5	aβ	aβ	NOUN
fnp-3025	630	6	-	-	PUNCT
fnp-3025	630	7	amyloid	amyloid	NOUN
fnp-3025	630	8	plaques	plaque	NOUN
fnp-3025	630	9	and	and	CCONJ
fnp-3025	630	10	tauopathy	tauopathy	NOUN
fnp-3025	630	11	become	become	VERB
fnp-3025	630	12	widespread	widespread	ADJ
fnp-3025	630	13	,	,	PUNCT
fnp-3025	630	14	especially	especially	ADV
fnp-3025	630	15	in	in	ADP
fnp-3025	630	16	neocortical	neocortical	ADJ
fnp-3025	630	17	regions	region	NOUN
fnp-3025	630	18	[	[	X
fnp-3025	630	19	1	1	NUM
fnp-3025	630	20	]	]	PUNCT
fnp-3025	630	21	,	,	PUNCT
fnp-3025	630	22	removing	remove	VERB
fnp-3025	630	23	the	the	DET
fnp-3025	630	24	plaques	plaque	NOUN
fnp-3025	630	25	is	be	AUX
fnp-3025	630	26	unlikely	unlikely	ADJ
fnp-3025	630	27	to	to	PART
fnp-3025	630	28	significantly	significantly	ADV
fnp-3025	630	29	reverse	reverse	VERB
fnp-3025	630	30	the	the	DET
fnp-3025	630	31	course	course	NOUN
fnp-3025	630	32	of	of	ADP
fnp-3025	630	33	dementia	dementia	NOUN
fnp-3025	630	34	.	.	PUNCT
fnp-3025	631	1	even	even	ADV
fnp-3025	631	2	so	so	ADV
fnp-3025	631	3	,	,	PUNCT
fnp-3025	631	4	there	there	PRON
fnp-3025	631	5	is	be	VERB
fnp-3025	631	6	evidence	evidence	NOUN
fnp-3025	631	7	that	that	SCONJ
fnp-3025	631	8	a	a	DET
fnp-3025	631	9	reduction	reduction	NOUN
fnp-3025	631	10	of	of	ADP
fnp-3025	631	11	tauopathy	tauopathy	NOUN
fnp-3025	631	12	[	[	X
fnp-3025	631	13	336	336	NUM
fnp-3025	631	14	]	]	PUNCT
fnp-3025	631	15	,	,	PUNCT
fnp-3025	631	16	and	and	CCONJ
fnp-3025	631	17	possibly	possibly	ADV
fnp-3025	631	18	some	some	DET
fnp-3025	631	19	cognitive	cognitive	ADJ
fnp-3025	631	20	benefit	benefit	NOUN
fnp-3025	631	21	,	,	PUNCT
fnp-3025	631	22	can	can	AUX
fnp-3025	631	23	be	be	AUX
fnp-3025	631	24	achieved	achieve	VERB
fnp-3025	631	25	in	in	ADP
fnp-3025	631	26	symptomatic	symptomatic	ADJ
fnp-3025	631	27	patients	patient	NOUN
fnp-3025	631	28	by	by	ADP
fnp-3025	631	29	anti	anti	ADJ
fnp-3025	631	30	-	-	ADJ
fnp-3025	631	31	aβ	aβ	ADJ
fnp-3025	631	32	immunotherapy	immunotherapy	NOUN
fnp-3025	631	33	[	[	X
fnp-3025	631	34	476	476	NUM
fnp-3025	631	35	,	,	PUNCT
fnp-3025	631	36	482	482	NUM
fnp-3025	631	37	-	-	SYM
fnp-3025	631	38	484	484	NUM
fnp-3025	631	39	]	]	PUNCT
fnp-3025	631	40	.	.	PUNCT
fnp-3025	632	1	indeed	indeed	ADV
fnp-3025	632	2	,	,	PUNCT
fnp-3025	632	3	active	active	ADJ
fnp-3025	632	4	immunization	immunization	NOUN
fnp-3025	632	5	with	with	ADP
fnp-3025	632	6	an1792	an1792	NOUN
fnp-3025	632	7	,	,	PUNCT
fnp-3025	632	8	which	which	PRON
fnp-3025	632	9	targets	target	VERB
fnp-3025	632	10	both	both	PRON
fnp-3025	632	11	aβ	aβ	ADP
fnp-3025	632	12	plaques	plaque	NOUN
fnp-3025	632	13	and	and	CCONJ
fnp-3025	632	14	oligomers	oligomer	NOUN
fnp-3025	632	15	,	,	PUNCT
fnp-3025	632	16	resulted	result	VERB
fnp-3025	632	17	in	in	ADP
fnp-3025	632	18	a	a	DET
fnp-3025	632	19	long	long	ADJ
fnp-3025	632	20	-	-	PUNCT
fnp-3025	632	21	term	term	NOUN
fnp-3025	632	22	decrease	decrease	NOUN
fnp-3025	632	23	in	in	ADP
fnp-3025	632	24	all	all	DET
fnp-3025	632	25	components	component	NOUN
fnp-3025	632	26	of	of	ADP
fnp-3025	632	27	the	the	DET
fnp-3025	632	28	plaques	plaque	NOUN
fnp-3025	632	29	aggregated	aggregate	VERB
fnp-3025	632	30	aβ	aβ	ADP
fnp-3025	632	31	,	,	PUNCT
fnp-3025	632	32	aberrant	aberrant	ADJ
fnp-3025	632	33	neurites	neurite	NOUN
fnp-3025	632	34	,	,	PUNCT
fnp-3025	632	35	tauopathy	tauopathy	ADJ
fnp-3025	632	36	,	,	PUNCT
fnp-3025	632	37	and	and	CCONJ
fnp-3025	632	38	focal	focal	ADJ
fnp-3025	632	39	gliopathy	gliopathy	NOUN
fnp-3025	632	40	along	along	ADP
fnp-3025	632	41	with	with	ADP
fnp-3025	632	42	improved	improved	ADJ
fnp-3025	632	43	indices	index	NOUN
fnp-3025	632	44	of	of	ADP
fnp-3025	632	45	‘	'	PUNCT
fnp-3025	632	46	neuronal	neuronal	ADJ
fnp-3025	632	47	health	health	NOUN
fnp-3025	632	48	’	'	PUNCT
fnp-3025	633	1	[	[	X
fnp-3025	633	2	336	336	NUM
fnp-3025	633	3	]	]	PUNCT
fnp-3025	633	4	.	.	PUNCT
fnp-3025	634	1	thus	thus	ADV
fnp-3025	634	2	,	,	PUNCT
fnp-3025	634	3	notwithstanding	notwithstanding	ADP
fnp-3025	634	4	the	the	DET
fnp-3025	634	5	mostly	mostly	ADV
fnp-3025	634	6	disheartening	disheartening	ADJ
fnp-3025	634	7	outcome	outcome	NOUN
fnp-3025	634	8	of	of	ADP
fnp-3025	634	9	therapeutic	therapeutic	ADJ
fnp-3025	634	10	trials	trial	NOUN
fnp-3025	634	11	to	to	ADP
fnp-3025	634	12	date	date	NOUN
fnp-3025	634	13	,	,	PUNCT
fnp-3025	634	14	current	current	ADJ
fnp-3025	634	15	preclinical	preclinical	ADJ
fnp-3025	634	16	and	and	CCONJ
fnp-3025	634	17	clinical	clinical	ADJ
fnp-3025	634	18	data	datum	NOUN
fnp-3025	634	19	indicate	indicate	VERB
fnp-3025	634	20	that	that	SCONJ
fnp-3025	634	21	the	the	DET
fnp-3025	634	22	right	right	ADJ
fnp-3025	634	23	anti	anti	ADJ
fnp-3025	634	24	-	-	ADJ
fnp-3025	634	25	aβ	aβ	ADJ
fnp-3025	634	26	treatment	treatment	NOUN
fnp-3025	634	27	,	,	PUNCT
fnp-3025	634	28	at	at	ADP
fnp-3025	634	29	the	the	DET
fnp-3025	634	30	right	right	ADJ
fnp-3025	634	31	time	time	NOUN
fnp-3025	634	32	,	,	PUNCT
fnp-3025	634	33	has	have	VERB
fnp-3025	634	34	a	a	DET
fnp-3025	634	35	good	good	ADJ
fnp-3025	634	36	chance	chance	NOUN
fnp-3025	634	37	of	of	ADP
fnp-3025	634	38	delaying	delay	VERB
fnp-3025	634	39	or	or	CCONJ
fnp-3025	634	40	preventing	prevent	VERB
fnp-3025	634	41	ad	ad	NOUN
fnp-3025	634	42	.	.	PUNCT
fnp-3025	635	1	finally	finally	ADV
fnp-3025	635	2	,	,	PUNCT
fnp-3025	635	3	it	it	PRON
fnp-3025	635	4	is	be	AUX
fnp-3025	635	5	imperative	imperative	ADJ
fnp-3025	635	6	to	to	PART
fnp-3025	635	7	remain	remain	VERB
fnp-3025	635	8	vigilant	vigilant	ADJ
fnp-3025	635	9	to	to	ADP
fnp-3025	635	10	the	the	DET
fnp-3025	635	11	impact	impact	NOUN
fnp-3025	635	12	of	of	ADP
fnp-3025	635	13	environmental	environmental	ADJ
fnp-3025	635	14	factors	factor	NOUN
fnp-3025	635	15	and	and	CCONJ
fnp-3025	635	16	the	the	DET
fnp-3025	635	17	microbiome	microbiome	NOUN
fnp-3025	635	18	[	[	X
fnp-3025	635	19	485	485	NUM
fnp-3025	635	20	,	,	PUNCT
fnp-3025	635	21	486	486	NUM
fnp-3025	635	22	]	]	PUNCT
fnp-3025	635	23	on	on	ADP
fnp-3025	635	24	the	the	DET
fnp-3025	635	25	risk	risk	NOUN
fnp-3025	635	26	of	of	ADP
fnp-3025	635	27	developing	develop	VERB
fnp-3025	635	28	ad	ad	NOUN
fnp-3025	635	29	.	.	PUNCT
fnp-3025	636	1	for	for	ADP
fnp-3025	636	2	instance	instance	NOUN
fnp-3025	636	3	,	,	PUNCT
fnp-3025	636	4	if	if	SCONJ
fnp-3025	636	5	specific	specific	ADJ
fnp-3025	636	6	microbes	microbe	NOUN
fnp-3025	636	7	are	be	AUX
fnp-3025	636	8	convincingly	convincingly	ADV
fnp-3025	636	9	found	find	VERB
fnp-3025	636	10	to	to	PART
fnp-3025	636	11	increase	increase	VERB
fnp-3025	636	12	the	the	DET
fnp-3025	636	13	risk	risk	NOUN
fnp-3025	636	14	of	of	ADP
fnp-3025	636	15	plaque	plaque	NOUN
fnp-3025	636	16	formation	formation	NOUN
fnp-3025	636	17	and	and	CCONJ
fnp-3025	636	18	ad	ad	NOUN
fnp-3025	636	19	,	,	PUNCT
fnp-3025	636	20	early	early	ADJ
fnp-3025	636	21	immunization	immunization	NOUN
fnp-3025	636	22	against	against	ADP
fnp-3025	636	23	this	this	DET
fnp-3025	636	24	infectious	infectious	ADJ
fnp-3025	636	25	agent	agent	NOUN
fnp-3025	636	26	could	could	AUX
fnp-3025	636	27	be	be	AUX
fnp-3025	636	28	an	an	DET
fnp-3025	636	29	effective	effective	ADJ
fnp-3025	636	30	preventive	preventive	ADJ
fnp-3025	636	31	measure	measure	NOUN
fnp-3025	636	32	.	.	PUNCT
fnp-3025	637	1	it	it	PRON
fnp-3025	637	2	is	be	AUX
fnp-3025	637	3	important	important	ADJ
fnp-3025	637	4	also	also	ADV
fnp-3025	637	5	to	to	PART
fnp-3025	637	6	consider	consider	VERB
fnp-3025	637	7	the	the	DET
fnp-3025	637	8	possibility	possibility	NOUN
fnp-3025	637	9	that	that	SCONJ
fnp-3025	637	10	interactions	interaction	NOUN
fnp-3025	637	11	among	among	ADP
fnp-3025	637	12	genetic	genetic	ADJ
fnp-3025	637	13	,	,	PUNCT
fnp-3025	637	14	microbiomic	microbiomic	ADJ
fnp-3025	637	15	and/or	and/or	CCONJ
fnp-3025	637	16	environmental	environmental	ADJ
fnp-3025	637	17	influences	influence	NOUN
fnp-3025	637	18	could	could	AUX
fnp-3025	637	19	raise	raise	VERB
fnp-3025	637	20	disease	disease	NOUN
fnp-3025	637	21	risk	risk	NOUN
fnp-3025	637	22	well	well	ADV
fnp-3025	637	23	above	above	ADP
fnp-3025	637	24	the	the	DET
fnp-3025	637	25	additive	additive	ADJ
fnp-3025	637	26	impact	impact	NOUN
fnp-3025	637	27	of	of	ADP
fnp-3025	637	28	individual	individual	ADJ
fnp-3025	637	29	risk	risk	NOUN
fnp-3025	637	30	factors	factor	NOUN
fnp-3025	637	31	.	.	PUNCT
fnp-3025	638	1	the	the	DET
fnp-3025	638	2	search	search	NOUN
fnp-3025	638	3	for	for	ADP
fnp-3025	638	4	disease	disease	NOUN
fnp-3025	638	5	-	-	PUNCT
fnp-3025	638	6	modifying	modify	VERB
fnp-3025	638	7	therapies	therapy	NOUN
fnp-3025	638	8	for	for	ADP
fnp-3025	638	9	ad	ad	NOUN
fnp-3025	638	10	is	be	AUX
fnp-3025	638	11	a	a	DET
fnp-3025	638	12	broad	broad	ADJ
fnp-3025	638	13	and	and	CCONJ
fnp-3025	638	14	rapidly	rapidly	ADV
fnp-3025	638	15	evolving	evolve	VERB
fnp-3025	638	16	endeavor	endeavor	NOUN
fnp-3025	638	17	that	that	PRON
fnp-3025	638	18	has	have	AUX
fnp-3025	638	19	been	be	AUX
fnp-3025	638	20	extensively	extensively	ADV
fnp-3025	638	21	reviewed	review	VERB
fnp-3025	638	22	(	(	PUNCT
fnp-3025	638	23	see	see	VERB
fnp-3025	638	24	,	,	PUNCT
fnp-3025	638	25	e.g.	e.g.	ADV
fnp-3025	638	26	,	,	PUNCT
fnp-3025	638	27	[	[	X
fnp-3025	638	28	9	9	NUM
fnp-3025	638	29	,	,	PUNCT
fnp-3025	638	30	33	33	NUM
fnp-3025	638	31	,	,	PUNCT
fnp-3025	638	32	476	476	NUM
fnp-3025	638	33	,	,	PUNCT
fnp-3025	638	34	479	479	NUM
fnp-3025	638	35	,	,	PUNCT
fnp-3025	638	36	487	487	NUM
fnp-3025	638	37	-	-	SYM
fnp-3025	638	38	491	491	NUM
fnp-3025	638	39	]	]	PUNCT
fnp-3025	638	40	.	.	PUNCT
fnp-3025	639	1	in	in	ADP
fnp-3025	639	2	addition	addition	NOUN
fnp-3025	639	3	to	to	ADP
fnp-3025	639	4	small	small	ADJ
fnp-3025	639	5	molecules	molecule	NOUN
fnp-3025	639	6	,	,	PUNCT
fnp-3025	639	7	we	we	PRON
fnp-3025	639	8	have	have	AUX
fnp-3025	639	9	entered	enter	VERB
fnp-3025	639	10	a	a	DET
fnp-3025	639	11	phase	phase	NOUN
fnp-3025	639	12	in	in	ADP
fnp-3025	639	13	medicine	medicine	NOUN
fnp-3025	639	14	in	in	ADP
fnp-3025	639	15	which	which	PRON
fnp-3025	639	16	biologics	biologic	NOUN
fnp-3025	639	17	such	such	ADJ
fnp-3025	639	18	as	as	ADP
fnp-3025	639	19	antibodies	antibody	NOUN
fnp-3025	639	20	[	[	X
fnp-3025	639	21	492	492	NUM
fnp-3025	639	22	,	,	PUNCT
fnp-3025	639	23	493	493	NUM
fnp-3025	639	24	]	]	PUNCT
fnp-3025	639	25	and	and	CCONJ
fnp-3025	639	26	nucleic	nucleic	ADJ
fnp-3025	639	27	acid	acid	NOUN
fnp-3025	639	28	-	-	PUNCT
fnp-3025	639	29	based	base	VERB
fnp-3025	639	30	agents	agent	NOUN
fnp-3025	639	31	[	[	X
fnp-3025	639	32	494	494	NUM
fnp-3025	639	33	,	,	PUNCT
fnp-3025	639	34	495	495	NUM
fnp-3025	639	35	]	]	PUNCT
fnp-3025	639	36	have	have	VERB
fnp-3025	639	37	unprecedented	unprecedented	ADJ
fnp-3025	639	38	potential	potential	NOUN
fnp-3025	639	39	to	to	PART
fnp-3025	639	40	treat	treat	VERB
fnp-3025	639	41	neurodegenerative	neurodegenerative	ADJ
fnp-3025	639	42	diseases	disease	NOUN
fnp-3025	639	43	.	.	PUNCT
fnp-3025	640	1	for	for	ADP
fnp-3025	640	2	well	well	ADV
fnp-3025	640	3	over	over	ADP
fnp-3025	640	4	a	a	DET
fnp-3025	640	5	century	century	NOUN
fnp-3025	640	6	,	,	PUNCT
fnp-3025	640	7	aβ	aβ	DET
fnp-3025	640	8	plaques	plaque	NOUN
fnp-3025	640	9	have	have	AUX
fnp-3025	640	10	been	be	AUX
fnp-3025	640	11	recognized	recognize	VERB
fnp-3025	640	12	as	as	ADP
fnp-3025	640	13	an	an	DET
fnp-3025	640	14	important	important	ADJ
fnp-3025	640	15	correlate	correlate	NOUN
fnp-3025	640	16	of	of	ADP
fnp-3025	640	17	dementia	dementia	NOUN
fnp-3025	640	18	in	in	ADP
fnp-3025	640	19	the	the	DET
fnp-3025	640	20	aging	age	VERB
fnp-3025	640	21	brain	brain	NOUN
fnp-3025	640	22	.	.	PUNCT
fnp-3025	641	1	revealing	reveal	VERB
fnp-3025	641	2	the	the	DET
fnp-3025	641	3	mechanisms	mechanism	NOUN
fnp-3025	641	4	by	by	ADP
fnp-3025	641	5	which	which	PRON
fnp-3025	641	6	plaques	plaque	NOUN
fnp-3025	641	7	arise	arise	VERB
fnp-3025	641	8	,	,	PUNCT
fnp-3025	641	9	proliferate	proliferate	VERB
fnp-3025	641	10	,	,	PUNCT
fnp-3025	641	11	and	and	CCONJ
fnp-3025	641	12	interact	interact	VERB
fnp-3025	641	13	with	with	ADP
fnp-3025	641	14	molecular	molecular	ADJ
fnp-3025	641	15	and	and	CCONJ
fnp-3025	641	16	cellular	cellular	ADJ
fnp-3025	641	17	elements	element	NOUN
fnp-3025	641	18	in	in	ADP
fnp-3025	641	19	the	the	DET
fnp-3025	641	20	nervous	nervous	ADJ
fnp-3025	641	21	system	system	NOUN
fnp-3025	641	22	will	will	AUX
fnp-3025	641	23	continue	continue	VERB
fnp-3025	641	24	to	to	PART
fnp-3025	641	25	yield	yield	VERB
fnp-3025	641	26	insights	insight	NOUN
fnp-3025	641	27	into	into	ADP
fnp-3025	641	28	both	both	CCONJ
fnp-3025	641	29	the	the	DET
fnp-3025	641	30	ontogeny	ontogeny	NOUN
fnp-3025	641	31	and	and	CCONJ
fnp-3025	641	32	treatment	treatment	NOUN
fnp-3025	641	33	of	of	ADP
fnp-3025	641	34	ad	ad	NOUN
fnp-3025	641	35	.	.	PUNCT
fnp-3025	642	1	12	12	NUM
fnp-3025	642	2	.	.	PUNCT
fnp-3025	643	1	methods	method	NOUN
fnp-3025	643	2	tissue	tissue	NOUN
fnp-3025	643	3	samples	sample	NOUN
fnp-3025	643	4	were	be	AUX
fnp-3025	643	5	collected	collect	VERB
fnp-3025	643	6	from	from	ADP
fnp-3025	643	7	human	human	ADJ
fnp-3025	643	8	subjects	subject	NOUN
fnp-3025	643	9	with	with	ADP
fnp-3025	643	10	end	end	NOUN
fnp-3025	643	11	-	-	PUNCT
fnp-3025	643	12	stage	stage	NOUN
fnp-3025	643	13	ad	ad	NOUN
fnp-3025	643	14	(	(	PUNCT
fnp-3025	643	15	figures	figure	NOUN
fnp-3025	643	16	1	1	NUM
fnp-3025	643	17	-	-	SYM
fnp-3025	643	18	6	6	NUM
fnp-3025	643	19	,	,	PUNCT
fnp-3025	643	20	8	8	NUM
fnp-3025	643	21	-	-	SYM
fnp-3025	643	22	20	20	NUM
fnp-3025	643	23	)	)	PUNCT
fnp-3025	643	24	and	and	CCONJ
fnp-3025	643	25	from	from	ADP
fnp-3025	643	26	aged	aged	ADJ
fnp-3025	643	27	nonhuman	nonhuman	ADJ
fnp-3025	643	28	species	specie	NOUN
fnp-3025	643	29	with	with	ADP
fnp-3025	643	30	cerebral	cerebral	ADJ
fnp-3025	643	31	aβ	aβ	NOUN
fnp-3025	643	32	deposition	deposition	NOUN
fnp-3025	643	33	(	(	PUNCT
fnp-3025	643	34	figures	figure	NOUN
fnp-3025	643	35	21	21	NUM
fnp-3025	643	36	-	-	SYM
fnp-3025	643	37	23	23	NUM
fnp-3025	643	38	)	)	PUNCT
fnp-3025	643	39	.	.	PUNCT
fnp-3025	644	1	postmortem	postmortem	NOUN
fnp-3025	644	2	collection	collection	NOUN
fnp-3025	644	3	of	of	ADP
fnp-3025	644	4	samples	sample	NOUN
fnp-3025	644	5	by	by	ADP
fnp-3025	644	6	the	the	DET
fnp-3025	644	7	emory	emory	PROPN
fnp-3025	644	8	university	university	PROPN
fnp-3025	644	9	goizueta	goizueta	PROPN
fnp-3025	644	10	alzheimer	alzheimer	PROPN
fnp-3025	644	11	’s	’s	PART
fnp-3025	644	12	disease	disease	PROPN
fnp-3025	644	13	research	research	NOUN
fnp-3025	644	14	center	center	PROPN
fnp-3025	644	15	brain	brain	NOUN
fnp-3025	644	16	bank	bank	PROPN
fnp-3025	644	17	was	be	AUX
fnp-3025	644	18	approved	approve	VERB
fnp-3025	644	19	by	by	ADP
fnp-3025	644	20	the	the	DET
fnp-3025	644	21	emory	emory	PROPN
fnp-3025	644	22	institutional	institutional	PROPN
fnp-3025	644	23	review	review	PROPN
fnp-3025	644	24	board	board	NOUN
fnp-3025	644	25	.	.	PUNCT
fnp-3025	645	1	tissues	tissue	NOUN
fnp-3025	645	2	from	from	ADP
fnp-3025	645	3	mice	mouse	NOUN
fnp-3025	645	4	and	and	CCONJ
fnp-3025	645	5	monkeys	monkey	NOUN
fnp-3025	645	6	were	be	AUX
fnp-3025	645	7	collected	collect	VERB
fnp-3025	645	8	at	at	ADP
fnp-3025	645	9	emory	emory	PROPN
fnp-3025	645	10	’s	’s	PART
fnp-3025	645	11	yerkes	yerke	NOUN
fnp-3025	645	12	national	national	ADJ
fnp-3025	645	13	primate	primate	NOUN
fnp-3025	645	14	research	research	NOUN
fnp-3025	645	15	center	center	NOUN
fnp-3025	645	16	in	in	ADP
fnp-3025	645	17	accordance	accordance	NOUN
fnp-3025	645	18	with	with	ADP
fnp-3025	645	19	federal	federal	ADJ
fnp-3025	645	20	and	and	CCONJ
fnp-3025	645	21	institutional	institutional	ADJ
fnp-3025	645	22	guidelines	guideline	NOUN
fnp-3025	645	23	for	for	ADP
fnp-3025	645	24	the	the	DET
fnp-3025	645	25	humane	humane	ADJ
fnp-3025	645	26	care	care	NOUN
fnp-3025	645	27	and	and	CCONJ
fnp-3025	645	28	use	use	NOUN
fnp-3025	645	29	of	of	ADP
fnp-3025	645	30	experimental	experimental	ADJ
fnp-3025	645	31	animals	animal	NOUN
fnp-3025	645	32	.	.	PUNCT
fnp-3025	646	1	the	the	DET
fnp-3025	646	2	yerkes	yerke	NOUN
fnp-3025	646	3	center	center	NOUN
fnp-3025	646	4	is	be	AUX
fnp-3025	646	5	fully	fully	ADV
fnp-3025	646	6	accredited	accredit	VERB
fnp-3025	646	7	by	by	ADP
fnp-3025	646	8	aaalac	aaalac	PROPN
fnp-3025	646	9	international	international	PROPN
fnp-3025	646	10	.	.	PUNCT
fnp-3025	647	1	12.1	12.1	NUM
fnp-3025	647	2	immunohistochemistry	immunohistochemistry	NOUN
fnp-3025	647	3	for	for	ADP
fnp-3025	647	4	light	light	ADJ
fnp-3025	647	5	-	-	PUNCT
fnp-3025	647	6	microscopy	microscopy	NOUN
fnp-3025	647	7	,	,	PUNCT
fnp-3025	647	8	tissue	tissue	NOUN
fnp-3025	647	9	blocks	block	NOUN
fnp-3025	647	10	were	be	AUX
fnp-3025	647	11	embedded	embed	VERB
fnp-3025	647	12	,	,	PUNCT
fnp-3025	647	13	sectioned	section	VERB
fnp-3025	647	14	at	at	ADP
fnp-3025	647	15	8	8	NUM
fnp-3025	647	16	-	-	SYM
fnp-3025	647	17	10	10	NUM
fnp-3025	647	18	μm	μm	NUM
fnp-3025	647	19	thickness	thickness	NOUN
fnp-3025	647	20	,	,	PUNCT
fnp-3025	647	21	and	and	CCONJ
fnp-3025	647	22	mounted	mount	VERB
fnp-3025	647	23	onto	onto	ADP
fnp-3025	647	24	glass	glass	NOUN
fnp-3025	647	25	slides	slide	NOUN
fnp-3025	647	26	for	for	ADP
fnp-3025	647	27	staining	stain	VERB
fnp-3025	647	28	.	.	PUNCT
fnp-3025	648	1	the	the	DET
fnp-3025	648	2	following	follow	VERB
fnp-3025	648	3	antibodies	antibody	NOUN
fnp-3025	648	4	were	be	AUX
fnp-3025	648	5	used	use	VERB
fnp-3025	648	6	for	for	ADP
fnp-3025	648	7	immunohistochemistry	immunohistochemistry	NOUN
fnp-3025	648	8	:	:	PUNCT
fnp-3025	648	9	4g8	4g8	NUM
fnp-3025	648	10	,	,	PUNCT
fnp-3025	648	11	mouse	mouse	NOUN
fnp-3025	648	12	monoclonal	monoclonal	NOUN
fnp-3025	648	13	antibody	antibody	NOUN
fnp-3025	648	14	from	from	ADP
fnp-3025	648	15	covance	covance	NOUN
fnp-3025	648	16	(	(	PUNCT
fnp-3025	648	17	princeton	princeton	PROPN
fnp-3025	648	18	,	,	PUNCT
fnp-3025	648	19	nj	nj	PROPN
fnp-3025	648	20	)	)	PUNCT
fnp-3025	648	21	raised	raise	VERB
fnp-3025	648	22	against	against	ADP
fnp-3025	648	23	residues	residue	NOUN
fnp-3025	648	24	17	17	NUM
fnp-3025	648	25	-	-	SYM
fnp-3025	648	26	24	24	NUM
fnp-3025	648	27	of	of	ADP
fnp-3025	648	28	aβ	aβ	NOUN
fnp-3025	648	29	peptide	peptide	NOUN
fnp-3025	648	30	,	,	PUNCT
fnp-3025	648	31	with	with	ADP
fnp-3025	648	32	an	an	DET
fnp-3025	648	33	epitope	epitope	NOUN
fnp-3025	648	34	at	at	ADP
fnp-3025	648	35	residues	residue	NOUN
fnp-3025	648	36	18	18	NUM
fnp-3025	648	37	-	-	SYM
fnp-3025	648	38	22	22	NUM
fnp-3025	649	1	[	[	X
fnp-3025	649	2	496	496	NUM
fnp-3025	649	3	]	]	X
fnp-3025	649	4	;	;	PUNCT
fnp-3025	649	5	6e10	6e10	NOUN
fnp-3025	649	6	,	,	PUNCT
fnp-3025	649	7	mouse	mouse	NOUN
fnp-3025	649	8	monoclonal	monoclonal	NOUN
fnp-3025	649	9	antibody	antibody	NOUN
fnp-3025	649	10	from	from	ADP
fnp-3025	649	11	covance	covance	NOUN
fnp-3025	649	12	raised	raise	VERB
fnp-3025	649	13	against	against	ADP
fnp-3025	649	14	residues	residue	NOUN
fnp-3025	649	15	1	1	NUM
fnp-3025	649	16	-	-	SYM
fnp-3025	649	17	16	16	NUM
fnp-3025	649	18	of	of	ADP
fnp-3025	649	19	the	the	DET
fnp-3025	649	20	aβ	aβ	NOUN
fnp-3025	649	21	peptide	peptide	NOUN
fnp-3025	649	22	,	,	PUNCT
fnp-3025	649	23	with	with	ADP
fnp-3025	649	24	an	an	DET
fnp-3025	649	25	epitope	epitope	NOUN
fnp-3025	649	26	at	at	ADP
fnp-3025	649	27	residues	residue	NOUN
fnp-3025	649	28	3	3	NUM
fnp-3025	649	29	-	-	SYM
fnp-3025	649	30	8	8	NUM
fnp-3025	649	31	[	[	X
fnp-3025	649	32	496	496	NUM
fnp-3025	649	33	]	]	X
fnp-3025	649	34	;	;	PUNCT
fnp-3025	649	35	rabbit	rabbit	NOUN
fnp-3025	649	36	polyclonal	polyclonal	NOUN
fnp-3025	649	37	antibodies	antibodie	VERB
fnp-3025	649	38	r361	r361	PROPN
fnp-3025	649	39	and	and	CCONJ
fnp-3025	649	40	r398	r398	PROPN
fnp-3025	649	41	,	,	PUNCT
fnp-3025	649	42	kindly	kindly	ADV
fnp-3025	649	43	provided	provide	VERB
fnp-3025	649	44	by	by	ADP
fnp-3025	649	45	dr	dr	PROPN
fnp-3025	649	46	.	.	PROPN
fnp-3025	649	47	pankaj	pankaj	PROPN
fnp-3025	649	48	mehta	mehta	PROPN
fnp-3025	649	49	(	(	PUNCT
fnp-3025	649	50	institute	institute	NOUN
fnp-3025	649	51	for	for	ADP
fnp-3025	649	52	basic	basic	ADJ
fnp-3025	649	53	research	research	NOUN
fnp-3025	649	54	on	on	ADP
fnp-3025	649	55	developmental	developmental	ADJ
fnp-3025	649	56	disabilities	disability	NOUN
fnp-3025	649	57	,	,	PUNCT
fnp-3025	649	58	staten	staten	PROPN
fnp-3025	649	59	island	island	NOUN
fnp-3025	649	60	,	,	PUNCT
fnp-3025	649	61	ny	ny	PROPN
fnp-3025	649	62	)	)	PUNCT
fnp-3025	649	63	,	,	PUNCT
fnp-3025	649	64	were	be	AUX
fnp-3025	649	65	raised	raise	VERB
fnp-3025	649	66	against	against	ADP
fnp-3025	649	67	synthetic	synthetic	ADJ
fnp-3025	649	68	aβ32	aβ32	PROPN
fnp-3025	649	69	-	-	PUNCT
fnp-3025	649	70	40	40	NUM
fnp-3025	649	71	and	and	CCONJ
fnp-3025	649	72	aβ33	aβ33	PROPN
fnp-3025	649	73	-	-	PUNCT
fnp-3025	649	74	42	42	NUM
fnp-3025	649	75	,	,	PUNCT
fnp-3025	649	76	respectively	respectively	ADV
fnp-3025	649	77	[	[	X
fnp-3025	649	78	497	497	NUM
fnp-3025	649	79	]	]	X
fnp-3025	649	80	;	;	PUNCT
fnp-3025	649	81	82e1	82e1	NUM
fnp-3025	649	82	,	,	PUNCT
fnp-3025	649	83	mouse	mouse	NOUN
fnp-3025	649	84	monoclonal	monoclonal	NOUN
fnp-3025	649	85	antibody	antibody	NOUN
fnp-3025	649	86	raised	raise	VERB
fnp-3025	649	87	against	against	ADP
fnp-3025	649	88	residues	residue	NOUN
fnp-3025	649	89	1	1	NUM
fnp-3025	649	90	-	-	SYM
fnp-3025	649	91	16	16	NUM
fnp-3025	649	92	of	of	ADP
fnp-3025	649	93	synthetic	synthetic	NOUN
fnp-3025	649	94	aβ	aβ	NOUN
fnp-3025	650	1	[	[	X
fnp-3025	650	2	498	498	NUM
fnp-3025	650	3	]	]	PUNCT
fnp-3025	650	4	,	,	PUNCT
fnp-3025	650	5	from	from	ADP
fnp-3025	650	6	ibl	ibl	PROPN
fnp-3025	650	7	(	(	PUNCT
fnp-3025	650	8	gunma	gunma	PROPN
fnp-3025	650	9	,	,	PUNCT
fnp-3025	650	10	japan	japan	PROPN
fnp-3025	650	11	)	)	PUNCT
fnp-3025	650	12	;	;	PUNCT
fnp-3025	650	13	cp13	cp13	PROPN
fnp-3025	650	14	,	,	PUNCT
fnp-3025	650	15	mouse	mouse	NOUN
fnp-3025	650	16	monoclonal	monoclonal	NOUN
fnp-3025	650	17	antibody	antibody	NOUN
fnp-3025	650	18	kindly	kindly	ADV
fnp-3025	650	19	provided	provide	VERB
fnp-3025	650	20	by	by	ADP
fnp-3025	650	21	dr	dr	PROPN
fnp-3025	650	22	.	.	PROPN
fnp-3025	650	23	peter	peter	PROPN
fnp-3025	650	24	davies	davies	PROPN
fnp-3025	650	25	(	(	PUNCT
fnp-3025	650	26	feinstein	feinstein	PROPN
fnp-3025	650	27	institutes	institutes	PROPN
fnp-3025	650	28	for	for	ADP
fnp-3025	650	29	medical	medical	ADJ
fnp-3025	650	30	research	research	NOUN
fnp-3025	650	31	,	,	PUNCT
fnp-3025	650	32	manhasset	manhasset	PROPN
fnp-3025	650	33	,	,	PUNCT
fnp-3025	650	34	ny	ny	PROPN
fnp-3025	650	35	)	)	PUNCT
fnp-3025	650	36	,	,	PUNCT
fnp-3025	650	37	was	be	AUX
fnp-3025	650	38	raised	raise	VERB
fnp-3025	650	39	against	against	ADP
fnp-3025	650	40	a	a	DET
fnp-3025	650	41	synthetic	synthetic	ADJ
fnp-3025	650	42	peptide	peptide	NOUN
fnp-3025	650	43	representing	represent	VERB
fnp-3025	650	44	the	the	DET
fnp-3025	650	45	region	region	NOUN
fnp-3025	650	46	around	around	ADP
fnp-3025	650	47	phosphorylated	phosphorylate	VERB
fnp-3025	650	48	serine	serine	NOUN
fnp-3025	650	49	residue	residue	NOUN
fnp-3025	650	50	202	202	NUM
fnp-3025	650	51	on	on	ADP
fnp-3025	650	52	the	the	DET
fnp-3025	650	53	tau	tau	PROPN
fnp-3025	650	54	protein	protein	NOUN
fnp-3025	650	55	[	[	X
fnp-3025	650	56	499	499	NUM
fnp-3025	650	57	]	]	PUNCT
fnp-3025	650	58	;	;	PUNCT
fnp-3025	650	59	mc1	mc1	PROPN
fnp-3025	650	60	,	,	PUNCT
fnp-3025	650	61	mouse	mouse	NOUN
fnp-3025	650	62	monoclonal	monoclonal	NOUN
fnp-3025	650	63	antibody	antibody	NOUN
fnp-3025	650	64	,	,	PUNCT
fnp-3025	650	65	also	also	ADV
fnp-3025	650	66	from	from	ADP
fnp-3025	650	67	dr	dr	PROPN
fnp-3025	650	68	.	.	PROPN
fnp-3025	650	69	davies	davy	NOUN
fnp-3025	650	70	,	,	PUNCT
fnp-3025	650	71	was	be	AUX
fnp-3025	650	72	raised	raise	VERB
fnp-3025	650	73	against	against	ADP
fnp-3025	650	74	alz50	alz50	PROPN
fnp-3025	650	75	-	-	PUNCT
fnp-3025	650	76	immunopurified	immunopurifie	VERB
fnp-3025	650	77	paired	pair	VERB
fnp-3025	650	78	helical	helical	ADJ
fnp-3025	650	79	filaments	filament	NOUN
fnp-3025	650	80	and	and	CCONJ
fnp-3025	650	81	then	then	ADV
fnp-3025	650	82	epitope	epitope	NOUN
fnp-3025	650	83	-	-	PUNCT
fnp-3025	650	84	mapped	map	VERB
fnp-3025	650	85	to	to	ADP
fnp-3025	650	86	similar	similar	ADJ
fnp-3025	650	87	conformation	conformation	NOUN
fnp-3025	650	88	-	-	PUNCT
fnp-3025	650	89	specific	specific	ADJ
fnp-3025	650	90	regions	region	NOUN
fnp-3025	650	91	as	as	ADP
fnp-3025	650	92	alz50	alz50	NOUN
fnp-3025	650	93	[	[	X
fnp-3025	650	94	500	500	NUM
fnp-3025	650	95	]	]	PUNCT
fnp-3025	650	96	;	;	PUNCT
fnp-3025	650	97	anti	anti	ADJ
fnp-3025	650	98	-	-	ADJ
fnp-3025	650	99	gfap	gfap	ADJ
fnp-3025	650	100	,	,	PUNCT
fnp-3025	650	101	purified	purified	ADJ
fnp-3025	650	102	immunoglobulin	immunoglobulin	NOUN
fnp-3025	650	103	fraction	fraction	NOUN
fnp-3025	650	104	of	of	ADP
fnp-3025	650	105	rabbit	rabbit	NOUN
fnp-3025	650	106	antiserum	antiserum	NOUN
fnp-3025	650	107	from	from	ADP
fnp-3025	650	108	dako	dako	PROPN
fnp-3025	650	109	(	(	PUNCT
fnp-3025	650	110	carpinteria	carpinteria	PROPN
fnp-3025	650	111	,	,	PUNCT
fnp-3025	650	112	ca	ca	NOUN
fnp-3025	650	113	)	)	PUNCT
fnp-3025	650	114	(	(	PUNCT
fnp-3025	650	115	catalog	catalog	NOUN
fnp-3025	650	116	no	no	NOUN
fnp-3025	650	117	.	.	PUNCT
fnp-3025	650	118	z0334	z0334	NUM
fnp-3025	650	119	)	)	PUNCT
fnp-3025	650	120	,	,	PUNCT
fnp-3025	650	121	raised	raise	VERB
fnp-3025	650	122	against	against	ADP
fnp-3025	650	123	gfap	gfap	NOUN
fnp-3025	650	124	isolated	isolate	VERB
fnp-3025	650	125	from	from	ADP
fnp-3025	650	126	cow	cow	NOUN
fnp-3025	650	127	spinal	spinal	NOUN
fnp-3025	650	128	cord	cord	NOUN
fnp-3025	650	129	and	and	CCONJ
fnp-3025	650	130	purified	purify	VERB
fnp-3025	650	131	by	by	ADP
fnp-3025	650	132	solid	solid	ADJ
fnp-3025	650	133	-	-	PUNCT
fnp-3025	650	134	phase	phase	NOUN
fnp-3025	650	135	absorption	absorption	NOUN
fnp-3025	650	136	with	with	ADP
fnp-3025	650	137	human	human	ADJ
fnp-3025	650	138	and	and	CCONJ
fnp-3025	650	139	cow	cow	NOUN
fnp-3025	650	140	serum	serum	NOUN
fnp-3025	650	141	proteins	protein	NOUN
fnp-3025	650	142	;	;	PUNCT
fnp-3025	650	143	anti	anti	ADJ
fnp-3025	650	144	-	-	ADJ
fnp-3025	650	145	iba1	iba1	ADJ
fnp-3025	650	146	,	,	PUNCT
fnp-3025	650	147	rabbit	rabbit	NOUN
fnp-3025	650	148	polyclonal	polyclonal	ADJ
fnp-3025	650	149	antibody	antibody	NOUN
fnp-3025	650	150	from	from	ADP
fnp-3025	650	151	wako	wako	PROPN
fnp-3025	650	152	(	(	PUNCT
fnp-3025	650	153	osaka	osaka	PROPN
fnp-3025	650	154	,	,	PUNCT
fnp-3025	650	155	japan	japan	PROPN
fnp-3025	650	156	)	)	PUNCT
fnp-3025	650	157	,	,	PUNCT
fnp-3025	650	158	raised	raise	VERB
fnp-3025	650	159	against	against	ADP
fnp-3025	650	160	a	a	DET
fnp-3025	650	161	synthetic	synthetic	ADJ
fnp-3025	650	162	peptide	peptide	NOUN
fnp-3025	650	163	corresponding	correspond	VERB
fnp-3025	650	164	to	to	ADP
fnp-3025	650	165	the	the	DET
fnp-3025	650	166	c	c	NOUN
fnp-3025	650	167	-	-	PUNCT
fnp-3025	650	168	terminus	terminus	NOUN
fnp-3025	650	169	of	of	ADP
fnp-3025	650	170	ionized	ionized	ADJ
fnp-3025	650	171	calcium	calcium	NOUN
fnp-3025	650	172	-	-	PUNCT
fnp-3025	650	173	binding	bind	VERB
fnp-3025	650	174	adapter	adapter	NOUN
fnp-3025	650	175	molecule	molecule	NOUN
fnp-3025	650	176	1	1	NUM
fnp-3025	650	177	(	(	PUNCT
fnp-3025	650	178	iba1	iba1	PROPN
fnp-3025	650	179	)	)	PUNCT
fnp-3025	650	180	,	,	PUNCT
fnp-3025	650	181	a	a	DET
fnp-3025	650	182	17	17	NUM
fnp-3025	650	183	-	-	PUNCT
fnp-3025	650	184	kda	kda	NOUN
fnp-3025	650	185	protein	protein	NOUN
fnp-3025	650	186	that	that	PRON
fnp-3025	650	187	is	be	AUX
fnp-3025	650	188	specifically	specifically	ADV
fnp-3025	650	189	expressed	express	VERB
fnp-3025	650	190	in	in	ADP
fnp-3025	650	191	macrophages	macrophage	NOUN
fnp-3025	650	192	/	/	SYM
fnp-3025	650	193	microglia	microglia	NOUN
fnp-3025	650	194	and	and	CCONJ
fnp-3025	650	195	is	be	AUX
fnp-3025	650	196	upregulated	upregulate	VERB
fnp-3025	650	197	during	during	ADP
fnp-3025	650	198	the	the	DET
fnp-3025	650	199	activation	activation	NOUN
fnp-3025	650	200	of	of	ADP
fnp-3025	650	201	these	these	DET
fnp-3025	650	202	cells	cell	NOUN
fnp-3025	650	203	[	[	X
fnp-3025	650	204	501	501	NUM
fnp-3025	650	205	,	,	PUNCT
fnp-3025	650	206	502	502	NUM
fnp-3025	650	207	]	]	X
fnp-3025	650	208	;	;	PUNCT
fnp-3025	650	209	smi-31	smi-31	NOUN
fnp-3025	650	210	,	,	PUNCT
fnp-3025	650	211	mouse	mouse	NOUN
fnp-3025	650	212	monoclonal	monoclonal	NOUN
fnp-3025	650	213	antibody	antibody	NOUN
fnp-3025	650	214	raised	raise	VERB
fnp-3025	650	215	against	against	ADP
fnp-3025	650	216	a	a	DET
fnp-3025	650	217	phosphorylated	phosphorylate	VERB
fnp-3025	650	218	epitope	epitope	NOUN
fnp-3025	650	219	on	on	ADP
fnp-3025	650	220	the	the	DET
fnp-3025	650	221	neurofilament	neurofilament	ADJ
fnp-3025	650	222	heavy	heavy	ADJ
fnp-3025	650	223	subunit	subunit	NOUN
fnp-3025	650	224	(	(	PUNCT
fnp-3025	650	225	nf	nf	NOUN
fnp-3025	650	226	-	-	PUNCT
fnp-3025	650	227	h	h	NOUN
fnp-3025	650	228	)	)	PUNCT
fnp-3025	651	1	[	[	X
fnp-3025	651	2	503	503	NUM
fnp-3025	651	3	]	]	PUNCT
fnp-3025	651	4	from	from	ADP
fnp-3025	651	5	biolegend	biolegend	PROPN
fnp-3025	651	6	(	(	PUNCT
fnp-3025	651	7	san	san	PROPN
fnp-3025	651	8	diego	diego	PROPN
fnp-3025	651	9	,	,	PUNCT
fnp-3025	651	10	ca	ca	NOUN
fnp-3025	651	11	)	)	PUNCT
fnp-3025	651	12	;	;	PUNCT
fnp-3025	651	13	and	and	CCONJ
fnp-3025	651	14	06	06	NUM
fnp-3025	651	15	-	-	SYM
fnp-3025	651	16	17	17	NUM
fnp-3025	651	17	,	,	PUNCT
fnp-3025	651	18	mouse	mouse	NOUN
fnp-3025	651	19	monoclonal	monoclonal	NOUN
fnp-3025	651	20	antibody	antibody	NOUN
fnp-3025	651	21	to	to	ADP
fnp-3025	651	22	a	a	DET
fnp-3025	651	23	phosphorylated	phosphorylate	VERB
fnp-3025	651	24	epitope	epitope	NOUN
fnp-3025	651	25	shared	share	VERB
fnp-3025	651	26	by	by	ADP
fnp-3025	651	27	the	the	DET
fnp-3025	651	28	heavy	heavy	ADJ
fnp-3025	651	29	and	and	CCONJ
fnp-3025	651	30	medium	medium	ADJ
fnp-3025	651	31	kda	kda	NOUN
fnp-3025	651	32	neurofilament	neurofilament	NOUN
fnp-3025	651	33	polypeptides	polypeptide	NOUN
fnp-3025	651	34	(	(	PUNCT
fnp-3025	651	35	generous	generous	ADJ
fnp-3025	651	36	gift	gift	NOUN
fnp-3025	651	37	of	of	ADP
fnp-3025	651	38	drs	dr	NOUN
fnp-3025	651	39	.	.	PUNCT
fnp-3025	652	1	ludwig	ludwig	PROPN
fnp-3025	652	2	and	and	CCONJ
fnp-3025	652	3	nancy	nancy	PROPN
fnp-3025	652	4	sternberger	sternberger	PROPN
fnp-3025	652	5	,	,	PUNCT
fnp-3025	652	6	university	university	PROPN
fnp-3025	652	7	of	of	ADP
fnp-3025	652	8	maryland	maryland	PROPN
fnp-3025	652	9	,	,	PUNCT
fnp-3025	652	10	baltimore	baltimore	PROPN
fnp-3025	652	11	)	)	PUNCT
fnp-3025	653	1	[	[	X
fnp-3025	653	2	504	504	NUM
fnp-3025	653	3	,	,	PUNCT
fnp-3025	653	4	505	505	NUM
fnp-3025	653	5	]	]	PUNCT
fnp-3025	653	6	.	.	PUNCT
fnp-3025	654	1	vectastain	vectastain	NOUN
fnp-3025	654	2	elite	elite	ADJ
fnp-3025	654	3	kits	kit	NOUN
fnp-3025	654	4	(	(	PUNCT
fnp-3025	654	5	vector	vector	NOUN
fnp-3025	654	6	laboratories	laboratory	NOUN
fnp-3025	654	7	,	,	PUNCT
fnp-3025	654	8	burlingame	burlingame	PROPN
fnp-3025	654	9	,	,	PUNCT
fnp-3025	654	10	ca	ca	NOUN
fnp-3025	654	11	)	)	PUNCT
fnp-3025	654	12	were	be	AUX
fnp-3025	654	13	used	use	VERB
fnp-3025	654	14	for	for	ADP
fnp-3025	654	15	abc	abc	PROPN
fnp-3025	654	16	-	-	PUNCT
fnp-3025	654	17	based	base	VERB
fnp-3025	654	18	immunodetection	immunodetection	NOUN
fnp-3025	654	19	of	of	ADP
fnp-3025	654	20	antigen	antigen	NOUN
fnp-3025	654	21	-	-	PUNCT
fnp-3025	654	22	antibody	antibody	NOUN
fnp-3025	654	23	complexes	complex	NOUN
fnp-3025	654	24	according	accord	VERB
fnp-3025	654	25	to	to	ADP
fnp-3025	654	26	the	the	DET
fnp-3025	654	27	manufacturer	manufacturer	NOUN
fnp-3025	654	28	’s	’s	PART
fnp-3025	654	29	instructions	instruction	NOUN
fnp-3025	654	30	,	,	PUNCT
fnp-3025	654	31	with	with	ADP
fnp-3025	654	32	diaminobenzidine	diaminobenzidine	NOUN
fnp-3025	654	33	(	(	PUNCT
fnp-3025	654	34	dab	dab	PROPN
fnp-3025	654	35	)	)	PUNCT
fnp-3025	654	36	as	as	ADP
fnp-3025	654	37	coloring	color	VERB
fnp-3025	654	38	agent	agent	NOUN
fnp-3025	654	39	for	for	ADP
fnp-3025	654	40	images	image	NOUN
fnp-3025	654	41	in	in	ADP
fnp-3025	654	42	figures	figure	NOUN
fnp-3025	654	43	1	1	NUM
fnp-3025	654	44	,	,	PUNCT
fnp-3025	654	45	2	2	NUM
fnp-3025	654	46	,	,	PUNCT
fnp-3025	654	47	5	5	NUM
fnp-3025	654	48	,	,	PUNCT
fnp-3025	654	49	6	6	NUM
fnp-3025	654	50	,	,	PUNCT
fnp-3025	654	51	8	8	NUM
fnp-3025	654	52	-	-	SYM
fnp-3025	654	53	11	11	NUM
fnp-3025	654	54	,	,	PUNCT
fnp-3025	654	55	14	14	NUM
fnp-3025	654	56	,	,	PUNCT
fnp-3025	654	57	16	16	NUM
fnp-3025	654	58	,	,	PUNCT
fnp-3025	654	59	17	17	NUM
fnp-3025	654	60	,	,	PUNCT
fnp-3025	654	61	19	19	NUM
fnp-3025	654	62	,	,	PUNCT
fnp-3025	654	63	21	21	NUM
fnp-3025	654	64	,	,	PUNCT
fnp-3025	654	65	&	&	CCONJ
fnp-3025	654	66	22	22	NUM
fnp-3025	654	67	.	.	PUNCT
fnp-3025	655	1	in	in	ADP
fnp-3025	655	2	most	most	ADJ
fnp-3025	655	3	cases	case	NOUN
fnp-3025	655	4	,	,	PUNCT
fnp-3025	655	5	a	a	DET
fnp-3025	655	6	nissl	nissl	ADJ
fnp-3025	655	7	counterstain	counterstain	NOUN
fnp-3025	655	8	was	be	AUX
fnp-3025	655	9	applied	apply	VERB
fnp-3025	655	10	after	after	ADP
fnp-3025	655	11	immunostaining	immunostaine	VERB
fnp-3025	655	12	,	,	PUNCT
fnp-3025	655	13	as	as	SCONJ
fnp-3025	655	14	noted	note	VERB
fnp-3025	655	15	.	.	PUNCT
fnp-3025	656	1	for	for	ADP
fnp-3025	656	2	dual	dual	ADJ
fnp-3025	656	3	fluorescence	fluorescence	NOUN
fnp-3025	656	4	immunostaining	immunostaine	VERB
fnp-3025	656	5	(	(	PUNCT
fnp-3025	656	6	figure	figure	NOUN
fnp-3025	656	7	15	15	NUM
fnp-3025	656	8	)	)	PUNCT
fnp-3025	656	9	,	,	PUNCT
fnp-3025	656	10	the	the	DET
fnp-3025	656	11	section	section	NOUN
fnp-3025	656	12	was	be	AUX
fnp-3025	656	13	incubated	incubate	VERB
fnp-3025	656	14	in	in	ADP
fnp-3025	656	15	mouse	mouse	NOUN
fnp-3025	656	16	monoclonal	monoclonal	NOUN
fnp-3025	656	17	antibody	antibody	NOUN
fnp-3025	656	18	cp13	cp13	PROPN
fnp-3025	656	19	(	(	PUNCT
fnp-3025	656	20	diluted	dilute	VERB
fnp-3025	656	21	in	in	ADP
fnp-3025	656	22	2	2	NUM
fnp-3025	656	23	%	%	NOUN
fnp-3025	656	24	normal	normal	ADJ
fnp-3025	656	25	goat	goat	PROPN
fnp-3025	656	26	serum	serum	PROPN
fnp-3025	656	27	)	)	PUNCT
fnp-3025	656	28	overnight	overnight	ADV
fnp-3025	656	29	at	at	ADP
fnp-3025	656	30	4	4	NUM
fnp-3025	656	31	°	°	NOUN
fnp-3025	656	32	c	c	NOUN
fnp-3025	656	33	,	,	PUNCT
fnp-3025	656	34	rinsed	rinse	VERB
fnp-3025	656	35	,	,	PUNCT
fnp-3025	656	36	and	and	CCONJ
fnp-3025	656	37	then	then	ADV
fnp-3025	656	38	incubated	incubate	VERB
fnp-3025	656	39	for	for	ADP
fnp-3025	656	40	90	90	NUM
fnp-3025	656	41	minutes	minute	NOUN
fnp-3025	656	42	in	in	ADP
fnp-3025	656	43	cy2	cy2	PROPN
fnp-3025	656	44	-	-	PUNCT
fnp-3025	656	45	conjugated	conjugate	VERB
fnp-3025	656	46	anti	anti	ADJ
fnp-3025	656	47	-	-	ADJ
fnp-3025	656	48	mouse	mouse	ADJ
fnp-3025	656	49	secondary	secondary	ADJ
fnp-3025	656	50	antibody	antibody	NOUN
fnp-3025	656	51	(	(	PUNCT
fnp-3025	656	52	green	green	ADJ
fnp-3025	656	53	;	;	PUNCT
fnp-3025	656	54	jackson	jackson	PROPN
fnp-3025	656	55	labs	labs	PROPN
fnp-3025	656	56	,	,	PUNCT
fnp-3025	656	57	west	west	PROPN
fnp-3025	656	58	grove	grove	PROPN
fnp-3025	656	59	,	,	PUNCT
fnp-3025	656	60	pa	pa	PROPN
fnp-3025	656	61	)	)	PUNCT
fnp-3025	656	62	.	.	PUNCT
fnp-3025	657	1	the	the	DET
fnp-3025	657	2	section	section	NOUN
fnp-3025	657	3	was	be	AUX
fnp-3025	657	4	rinsed	rinse	VERB
fnp-3025	657	5	thoroughly	thoroughly	ADV
fnp-3025	657	6	,	,	PUNCT
fnp-3025	657	7	incubated	incubate	VERB
fnp-3025	657	8	overnight	overnight	ADV
fnp-3025	657	9	in	in	ADP
fnp-3025	657	10	diluted	diluted	ADJ
fnp-3025	657	11	rabbit	rabbit	NOUN
fnp-3025	657	12	polyclonal	polyclonal	ADJ
fnp-3025	657	13	antibody	antibody	NOUN
fnp-3025	657	14	r398	r398	PROPN
fnp-3025	657	15	at	at	ADP
fnp-3025	657	16	4	4	NUM
fnp-3025	657	17	°	°	NOUN
fnp-3025	657	18	c	c	NOUN
fnp-3025	657	19	,	,	PUNCT
fnp-3025	657	20	rinsed	rinse	VERB
fnp-3025	657	21	,	,	PUNCT
fnp-3025	657	22	and	and	CCONJ
fnp-3025	657	23	placed	place	VERB
fnp-3025	657	24	for	for	ADP
fnp-3025	657	25	90	90	NUM
fnp-3025	657	26	minutes	minute	NOUN
fnp-3025	657	27	in	in	ADP
fnp-3025	657	28	rhodamine	rhodamine	ADJ
fnp-3025	657	29	-	-	PUNCT
fnp-3025	657	30	red	red	VERB
fnp-3025	657	31	-	-	PUNCT
fnp-3025	657	32	x	x	PROPN
fnp-3025	657	33	goat	goat	PROPN
fnp-3025	657	34	anti	anti	ADJ
fnp-3025	657	35	-	-	ADJ
fnp-3025	657	36	rabbit	rabbit	ADJ
fnp-3025	657	37	secondary	secondary	ADJ
fnp-3025	657	38	antibody	antibody	NOUN
fnp-3025	657	39	(	(	PUNCT
fnp-3025	657	40	jackson	jackson	PROPN
fnp-3025	657	41	labs	labs	PROPN
fnp-3025	657	42	)	)	PUNCT
fnp-3025	657	43	.	.	PUNCT
fnp-3025	658	1	for	for	ADP
fnp-3025	658	2	dual	dual	ADJ
fnp-3025	658	3	immunostaining	immunostaine	VERB
fnp-3025	658	4	by	by	ADP
fnp-3025	658	5	standard	standard	ADJ
fnp-3025	658	6	transillumination	transillumination	NOUN
fnp-3025	658	7	light	light	NOUN
fnp-3025	658	8	microscopy	microscopy	NOUN
fnp-3025	658	9	(	(	PUNCT
fnp-3025	658	10	figure	figure	NOUN
fnp-3025	658	11	3	3	NUM
fnp-3025	658	12	)	)	PUNCT
fnp-3025	658	13	,	,	PUNCT
fnp-3025	658	14	antibodies	antibodie	VERB
fnp-3025	658	15	were	be	AUX
fnp-3025	658	16	sequentially	sequentially	ADV
fnp-3025	658	17	applied	apply	VERB
fnp-3025	658	18	as	as	SCONJ
fnp-3025	658	19	described	describe	VERB
fnp-3025	658	20	above	above	ADV
fnp-3025	658	21	except	except	SCONJ
fnp-3025	658	22	that	that	SCONJ
fnp-3025	658	23	the	the	DET
fnp-3025	658	24	polyclonal	polyclonal	ADJ
fnp-3025	658	25	anti	anti	ADJ
fnp-3025	658	26	-	-	ADJ
fnp-3025	658	27	aβ	aβ	ADJ
fnp-3025	658	28	antibodies	antibodie	VERB
fnp-3025	658	29	r398+r361	r398+r361	NOUN
fnp-3025	658	30	were	be	AUX
fnp-3025	658	31	colored	color	VERB
fnp-3025	658	32	with	with	ADP
fnp-3025	658	33	dab	dab	PROPN
fnp-3025	658	34	(	(	PUNCT
fnp-3025	658	35	brown	brown	PROPN
fnp-3025	658	36	)	)	PUNCT
fnp-3025	658	37	,	,	PUNCT
fnp-3025	658	38	and	and	CCONJ
fnp-3025	658	39	the	the	DET
fnp-3025	658	40	anti	anti	ADJ
fnp-3025	658	41	-	-	ADJ
fnp-3025	658	42	tau	tau	ADJ
fnp-3025	658	43	monoclonal	monoclonal	NOUN
fnp-3025	658	44	antibody	antibody	NOUN
fnp-3025	658	45	cp13	cp13	PROPN
fnp-3025	658	46	was	be	AUX
fnp-3025	658	47	colored	color	VERB
fnp-3025	658	48	with	with	ADP
fnp-3025	658	49	vip	vip	NOUN
fnp-3025	658	50	(	(	PUNCT
fnp-3025	658	51	purple	purple	ADJ
fnp-3025	658	52	;	;	PUNCT
fnp-3025	658	53	vector	vector	NOUN
fnp-3025	658	54	laboratories	laboratory	NOUN
fnp-3025	658	55	)	)	PUNCT
fnp-3025	658	56	.	.	PUNCT
fnp-3025	659	1	non	non	ADJ
fnp-3025	659	2	-	-	ADJ
fnp-3025	659	3	immune	immune	ADJ
fnp-3025	659	4	mouse	mouse	NOUN
fnp-3025	659	5	igg	igg	NOUN
fnp-3025	659	6	or	or	CCONJ
fnp-3025	659	7	rabbit	rabbit	NOUN
fnp-3025	659	8	sera	sera	NOUN
fnp-3025	659	9	were	be	AUX
fnp-3025	659	10	used	use	VERB
fnp-3025	659	11	in	in	ADP
fnp-3025	659	12	place	place	NOUN
fnp-3025	659	13	of	of	ADP
fnp-3025	659	14	the	the	DET
fnp-3025	659	15	primary	primary	ADJ
fnp-3025	659	16	antibodies	antibody	NOUN
fnp-3025	659	17	as	as	ADP
fnp-3025	659	18	negative	negative	ADJ
fnp-3025	659	19	controls	control	NOUN
fnp-3025	659	20	.	.	PUNCT
fnp-3025	660	1	tissues	tissue	NOUN
fnp-3025	660	2	shown	show	VERB
fnp-3025	660	3	in	in	ADP
fnp-3025	660	4	figures	figure	NOUN
fnp-3025	660	5	1	1	NUM
fnp-3025	660	6	(	(	PUNCT
fnp-3025	660	7	left	leave	VERB
fnp-3025	660	8	)	)	PUNCT
fnp-3025	660	9	and	and	CCONJ
fnp-3025	660	10	4	4	NUM
fnp-3025	660	11	were	be	AUX
fnp-3025	660	12	stained	stain	VERB
fnp-3025	660	13	with	with	ADP
fnp-3025	660	14	the	the	DET
fnp-3025	660	15	naoumenko	naoumenko	NOUN
fnp-3025	660	16	-	-	PUNCT
fnp-3025	660	17	feigin	feigin	NOUN
fnp-3025	660	18	silver	silver	NOUN
fnp-3025	660	19	stain	stain	NOUN
fnp-3025	660	20	[	[	X
fnp-3025	660	21	506	506	NUM
fnp-3025	660	22	]	]	PUNCT
fnp-3025	660	23	followed	follow	VERB
fnp-3025	660	24	by	by	ADP
fnp-3025	660	25	a	a	DET
fnp-3025	660	26	periodic	periodic	ADJ
fnp-3025	660	27	acid	acid	NOUN
fnp-3025	660	28	-	-	PUNCT
fnp-3025	660	29	schiff	schiff	NOUN
fnp-3025	660	30	(	(	PUNCT
fnp-3025	660	31	pas	pas	NOUN
fnp-3025	660	32	)	)	PUNCT
fnp-3025	660	33	counterstain	counterstain	NOUN
fnp-3025	660	34	.	.	PUNCT
fnp-3025	661	1	figure	figure	NOUN
fnp-3025	661	2	23	23	NUM
fnp-3025	661	3	was	be	AUX
fnp-3025	661	4	stained	stain	VERB
fnp-3025	661	5	with	with	ADP
fnp-3025	661	6	the	the	DET
fnp-3025	661	7	campbell	campbell	PROPN
fnp-3025	661	8	-	-	PUNCT
fnp-3025	661	9	gallyas	gallyas	PROPN
fnp-3025	661	10	silver	silver	NOUN
fnp-3025	661	11	stain	stain	NOUN
fnp-3025	661	12	[	[	X
fnp-3025	661	13	507	507	NUM
fnp-3025	661	14	]	]	PUNCT
fnp-3025	661	15	.	.	PUNCT
fnp-3025	662	1	light	light	ADJ
fnp-3025	662	2	-	-	PUNCT
fnp-3025	662	3	microscopic	microscopic	ADJ
fnp-3025	662	4	photomicrographs	photomicrograph	NOUN
fnp-3025	662	5	were	be	AUX
fnp-3025	662	6	taken	take	VERB
fnp-3025	662	7	with	with	ADP
fnp-3025	662	8	a	a	DET
fnp-3025	662	9	leica	leica	PROPN
fnp-3025	662	10	dmlb	dmlb	PROPN
fnp-3025	662	11	or	or	CCONJ
fnp-3025	662	12	dmls	dmls	VERB
fnp-3025	662	13	microscope	microscope	NOUN
fnp-3025	662	14	(	(	PUNCT
fnp-3025	662	15	wetzlar	wetzlar	ADJ
fnp-3025	662	16	,	,	PUNCT
fnp-3025	662	17	germany	germany	PROPN
fnp-3025	662	18	)	)	PUNCT
fnp-3025	662	19	and	and	CCONJ
fnp-3025	662	20	a	a	DET
fnp-3025	662	21	spot	spot	NOUN
fnp-3025	662	22	flex	flex	ADJ
fnp-3025	662	23	(	(	PUNCT
fnp-3025	662	24	diagnostic	diagnostic	ADJ
fnp-3025	662	25	instruments	instrument	NOUN
fnp-3025	662	26	,	,	PUNCT
fnp-3025	662	27	sterling	sterling	NOUN
fnp-3025	662	28	heights	height	NOUN
fnp-3025	662	29	,	,	PUNCT
fnp-3025	662	30	mi	mi	NOUN
fnp-3025	662	31	)	)	PUNCT
fnp-3025	662	32	or	or	CCONJ
fnp-3025	662	33	moticam	moticam	VERB
fnp-3025	662	34	5	5	NUM
fnp-3025	662	35	+	+	CCONJ
fnp-3025	662	36	(	(	PUNCT
fnp-3025	662	37	motic	motic	ADJ
fnp-3025	662	38	,	,	PUNCT
fnp-3025	662	39	hong	hong	PROPN
fnp-3025	662	40	kong	kong	PROPN
fnp-3025	662	41	)	)	PUNCT
fnp-3025	662	42	digital	digital	ADJ
fnp-3025	662	43	camera	camera	NOUN
fnp-3025	662	44	.	.	PUNCT
fnp-3025	663	1	12.2	12.2	NUM
fnp-3025	663	2	electron	electron	NOUN
fnp-3025	663	3	microscopy	microscopy	NOUN
fnp-3025	663	4	for	for	ADP
fnp-3025	663	5	conventional	conventional	ADJ
fnp-3025	663	6	ultrastructural	ultrastructural	ADJ
fnp-3025	663	7	analysis	analysis	NOUN
fnp-3025	663	8	(	(	PUNCT
fnp-3025	663	9	figures	figure	NOUN
fnp-3025	663	10	12	12	NUM
fnp-3025	663	11	,	,	PUNCT
fnp-3025	663	12	13	13	NUM
fnp-3025	663	13	,	,	PUNCT
fnp-3025	663	14	18	18	NUM
fnp-3025	663	15	,	,	PUNCT
fnp-3025	663	16	20	20	NUM
fnp-3025	663	17	)	)	PUNCT
fnp-3025	663	18	,	,	PUNCT
fnp-3025	663	19	small	small	ADJ
fnp-3025	663	20	blocks	block	NOUN
fnp-3025	663	21	of	of	ADP
fnp-3025	663	22	cortex	cortex	NOUN
fnp-3025	663	23	were	be	AUX
fnp-3025	663	24	sub	sub	ADJ
fnp-3025	663	25	-	-	ADJ
fnp-3025	663	26	dissected	dissected	ADJ
fnp-3025	663	27	from	from	ADP
fnp-3025	663	28	larger	large	ADJ
fnp-3025	663	29	,	,	PUNCT
fnp-3025	663	30	autopsy	autopsy	ADJ
fnp-3025	663	31	-	-	PUNCT
fnp-3025	663	32	derived	derive	VERB
fnp-3025	663	33	tissue	tissue	NOUN
fnp-3025	663	34	blocks	block	NOUN
fnp-3025	663	35	that	that	PRON
fnp-3025	663	36	had	have	AUX
fnp-3025	663	37	been	be	AUX
fnp-3025	663	38	immersion	immersion	NOUN
fnp-3025	663	39	-	-	PUNCT
fnp-3025	663	40	fixed	fix	VERB
fnp-3025	663	41	in	in	ADP
fnp-3025	663	42	10	10	NUM
fnp-3025	663	43	%	%	NOUN
fnp-3025	663	44	neutral	neutral	ADJ
fnp-3025	663	45	buffered	buffer	VERB
fnp-3025	663	46	formalin	formalin	NOUN
fnp-3025	663	47	.	.	PUNCT
fnp-3025	664	1	the	the	DET
fnp-3025	664	2	tissue	tissue	NOUN
fnp-3025	664	3	samples	sample	NOUN
fnp-3025	664	4	were	be	AUX
fnp-3025	664	5	washed	wash	VERB
fnp-3025	664	6	in	in	ADP
fnp-3025	664	7	phosphate	phosphate	ADJ
fnp-3025	664	8	buffer	buffer	NOUN
fnp-3025	664	9	(	(	PUNCT
fnp-3025	664	10	0.1	0.1	NUM
fnp-3025	664	11	m	m	NOUN
fnp-3025	664	12	,	,	PUNCT
fnp-3025	664	13	ph	ph	VERB
fnp-3025	664	14	7.4	7.4	NUM
fnp-3025	664	15	)	)	PUNCT
fnp-3025	664	16	and	and	CCONJ
fnp-3025	664	17	immersed	immerse	VERB
fnp-3025	664	18	in	in	ADP
fnp-3025	664	19	osmium	osmium	NOUN
fnp-3025	664	20	tetroxide	tetroxide	NOUN
fnp-3025	664	21	(	(	PUNCT
fnp-3025	664	22	1	1	NUM
fnp-3025	664	23	%	%	NOUN
fnp-3025	664	24	in	in	ADP
fnp-3025	664	25	phosphate	phosphate	ADJ
fnp-3025	664	26	buffer	buffer	NOUN
fnp-3025	664	27	)	)	PUNCT
fnp-3025	664	28	for	for	ADP
fnp-3025	664	29	20	20	NUM
fnp-3025	664	30	minutes	minute	NOUN
fnp-3025	664	31	.	.	PUNCT
fnp-3025	665	1	they	they	PRON
fnp-3025	665	2	were	be	AUX
fnp-3025	665	3	then	then	ADV
fnp-3025	665	4	rinsed	rinse	VERB
fnp-3025	665	5	in	in	ADP
fnp-3025	665	6	phosphate	phosphate	ADJ
fnp-3025	665	7	buffer	buffer	NOUN
fnp-3025	665	8	and	and	CCONJ
fnp-3025	665	9	dehydrated	dehydrate	VERB
fnp-3025	665	10	in	in	ADP
fnp-3025	665	11	a	a	DET
fnp-3025	665	12	graded	grade	VERB
fnp-3025	665	13	series	series	NOUN
fnp-3025	665	14	of	of	ADP
fnp-3025	665	15	ethanol	ethanol	NOUN
fnp-3025	665	16	and	and	CCONJ
fnp-3025	665	17	propylene	propylene	NOUN
fnp-3025	665	18	oxide	oxide	NOUN
fnp-3025	665	19	.	.	PUNCT
fnp-3025	666	1	uranyl	uranyl	NOUN
fnp-3025	666	2	acetate	acetate	NOUN
fnp-3025	666	3	(	(	PUNCT
fnp-3025	666	4	1	1	NUM
fnp-3025	666	5	%	%	NOUN
fnp-3025	666	6	)	)	PUNCT
fnp-3025	666	7	was	be	AUX
fnp-3025	666	8	added	add	VERB
fnp-3025	666	9	to	to	ADP
fnp-3025	666	10	the	the	DET
fnp-3025	666	11	70	70	NUM
fnp-3025	666	12	%	%	NOUN
fnp-3025	666	13	ethanol	ethanol	NOUN
fnp-3025	666	14	(	(	PUNCT
fnp-3025	666	15	35	35	NUM
fnp-3025	666	16	minute	minute	NOUN
fnp-3025	666	17	immersion	immersion	NOUN
fnp-3025	666	18	)	)	PUNCT
fnp-3025	666	19	to	to	PART
fnp-3025	666	20	improve	improve	VERB
fnp-3025	666	21	contrast	contrast	NOUN
fnp-3025	666	22	in	in	ADP
fnp-3025	666	23	the	the	DET
fnp-3025	666	24	electron	electron	NOUN
fnp-3025	666	25	microscope	microscope	NOUN
fnp-3025	666	26	.	.	PUNCT
fnp-3025	667	1	the	the	DET
fnp-3025	667	2	sections	section	NOUN
fnp-3025	667	3	were	be	AUX
fnp-3025	667	4	then	then	ADV
fnp-3025	667	5	embedded	embed	VERB
fnp-3025	667	6	in	in	ADP
fnp-3025	667	7	epoxy	epoxy	NOUN
fnp-3025	667	8	resin	resin	NOUN
fnp-3025	667	9	(	(	PUNCT
fnp-3025	667	10	durcupan	durcupan	VERB
fnp-3025	667	11	acm	acm	NOUN
fnp-3025	667	12	;	;	PUNCT
fnp-3025	667	13	fluka	fluka	NOUN
fnp-3025	667	14	,	,	PUNCT
fnp-3025	667	15	ft	ft	PROPN
fnp-3025	667	16	.	.	PROPN
fnp-3025	667	17	washington	washington	PROPN
fnp-3025	667	18	,	,	PUNCT
fnp-3025	667	19	pa	pa	PROPN
fnp-3025	667	20	)	)	PUNCT
fnp-3025	667	21	on	on	ADP
fnp-3025	667	22	microscope	microscope	NOUN
fnp-3025	667	23	slides	slide	NOUN
fnp-3025	667	24	and	and	CCONJ
fnp-3025	667	25	heated	heat	VERB
fnp-3025	667	26	for	for	ADP
fnp-3025	667	27	48	48	NUM
fnp-3025	667	28	hours	hour	NOUN
fnp-3025	667	29	at	at	ADP
fnp-3025	667	30	60	60	NUM
fnp-3025	667	31	°	°	NOUN
fnp-3025	667	32	c	c	NOUN
fnp-3025	667	33	.	.	PUNCT
fnp-3025	668	1	areas	area	NOUN
fnp-3025	668	2	of	of	ADP
fnp-3025	668	3	interest	interest	NOUN
fnp-3025	668	4	were	be	AUX
fnp-3025	668	5	selected	select	VERB
fnp-3025	668	6	,	,	PUNCT
fnp-3025	668	7	excised	excise	VERB
fnp-3025	668	8	from	from	ADP
fnp-3025	668	9	the	the	DET
fnp-3025	668	10	slide	slide	NOUN
fnp-3025	668	11	and	and	CCONJ
fnp-3025	668	12	glued	glue	VERB
fnp-3025	668	13	onto	onto	ADP
fnp-3025	668	14	resin	resin	NOUN
fnp-3025	668	15	blocks	block	NOUN
fnp-3025	668	16	.	.	PUNCT
fnp-3025	669	1	ultrathin	ultrathin	ADJ
fnp-3025	669	2	sections	section	NOUN
fnp-3025	669	3	were	be	AUX
fnp-3025	669	4	cut	cut	VERB
fnp-3025	669	5	with	with	ADP
fnp-3025	669	6	a	a	DET
fnp-3025	669	7	leica	leica	PROPN
fnp-3025	669	8	ultracut	ultracut	VERB
fnp-3025	669	9	t2	t2	PROPN
fnp-3025	669	10	(	(	PUNCT
fnp-3025	669	11	nussloch	nussloch	PROPN
fnp-3025	669	12	,	,	PUNCT
fnp-3025	669	13	germany	germany	PROPN
fnp-3025	669	14	)	)	PUNCT
fnp-3025	669	15	,	,	PUNCT
fnp-3025	669	16	collected	collect	VERB
fnp-3025	669	17	onto	onto	ADP
fnp-3025	669	18	single	single	ADJ
fnp-3025	669	19	-	-	PUNCT
fnp-3025	669	20	slot	slot	NOUN
fnp-3025	669	21	copper	copper	NOUN
fnp-3025	669	22	grids	grid	NOUN
fnp-3025	669	23	,	,	PUNCT
fnp-3025	669	24	and	and	CCONJ
fnp-3025	669	25	stained	stain	VERB
fnp-3025	669	26	with	with	ADP
fnp-3025	669	27	lead	lead	ADJ
fnp-3025	669	28	citrate	citrate	NOUN
fnp-3025	669	29	.	.	PUNCT
fnp-3025	670	1	for	for	ADP
fnp-3025	670	2	immunogold	immunogold	ADJ
fnp-3025	670	3	em	em	PRON
fnp-3025	670	4	(	(	PUNCT
fnp-3025	670	5	figure	figure	NOUN
fnp-3025	670	6	11	11	NUM
fnp-3025	670	7	,	,	PUNCT
fnp-3025	670	8	right	right	ADJ
fnp-3025	670	9	)	)	PUNCT
fnp-3025	670	10	,	,	PUNCT
fnp-3025	670	11	sections	section	NOUN
fnp-3025	670	12	were	be	AUX
fnp-3025	670	13	preincubated	preincubate	VERB
fnp-3025	670	14	in	in	ADP
fnp-3025	670	15	pbs	pbs	NOUN
fnp-3025	670	16	containing	contain	VERB
fnp-3025	670	17	5	5	NUM
fnp-3025	670	18	%	%	NOUN
fnp-3025	670	19	nonfat	nonfat	NOUN
fnp-3025	670	20	dry	dry	ADJ
fnp-3025	670	21	milk	milk	NOUN
fnp-3025	670	22	and	and	CCONJ
fnp-3025	670	23	then	then	ADV
fnp-3025	670	24	washed	wash	VERB
fnp-3025	670	25	in	in	ADP
fnp-3025	670	26	tris	tris	ADJ
fnp-3025	670	27	-	-	PUNCT
fnp-3025	670	28	buffered	buffer	VERB
fnp-3025	670	29	saline	saline	NOUN
fnp-3025	670	30	(	(	PUNCT
fnp-3025	670	31	tbs)-gelatin	tbs)-gelatin	ADJ
fnp-3025	670	32	buffer	buffer	NOUN
fnp-3025	670	33	(	(	PUNCT
fnp-3025	670	34	0.02	0.02	NUM
fnp-3025	670	35	m	m	NOUN
fnp-3025	670	36	tris	tris	NOUN
fnp-3025	670	37	,	,	PUNCT
fnp-3025	670	38	0.15	0.15	NUM
fnp-3025	670	39	m	m	NOUN
fnp-3025	670	40	nacl	nacl	ADJ
fnp-3025	670	41	,	,	PUNCT
fnp-3025	670	42	1	1	NUM
fnp-3025	670	43	μl	μl	PRON
fnp-3025	670	44	/	/	SYM
fnp-3025	670	45	ml	ml	NOUN
fnp-3025	670	46	fish	fish	NOUN
fnp-3025	670	47	gelatin	gelatin	NOUN
fnp-3025	670	48	,	,	PUNCT
fnp-3025	670	49	ph	ph	NOUN
fnp-3025	670	50	7.6	7.6	NUM
fnp-3025	670	51	)	)	PUNCT
fnp-3025	670	52	to	to	PART
fnp-3025	670	53	block	block	VERB
fnp-3025	670	54	nonspecific	nonspecific	ADJ
fnp-3025	670	55	sites	site	NOUN
fnp-3025	670	56	.	.	PUNCT
fnp-3025	671	1	sections	section	NOUN
fnp-3025	671	2	were	be	AUX
fnp-3025	671	3	then	then	ADV
fnp-3025	671	4	incubated	incubate	VERB
fnp-3025	671	5	for	for	ADP
fnp-3025	671	6	48	48	NUM
fnp-3025	671	7	hours	hour	NOUN
fnp-3025	671	8	at	at	ADP
fnp-3025	671	9	4	4	NUM
fnp-3025	671	10	°	°	ADP
fnp-3025	671	11	c	c	NOUN
fnp-3025	671	12	with	with	ADP
fnp-3025	671	13	antibody	antibody	NOUN
fnp-3025	671	14	4g8	4g8	NUM
fnp-3025	671	15	diluted	dilute	VERB
fnp-3025	671	16	in	in	ADP
fnp-3025	671	17	pbs	pbs	PROPN
fnp-3025	671	18	-	-	PUNCT
fnp-3025	671	19	bsa	bsa	PROPN
fnp-3025	671	20	,	,	PUNCT
fnp-3025	671	21	rinsed	rinse	VERB
fnp-3025	671	22	in	in	ADP
fnp-3025	671	23	tbs	tbs	NOUN
fnp-3025	671	24	-	-	PUNCT
fnp-3025	671	25	gelatin	gelatin	NOUN
fnp-3025	671	26	,	,	PUNCT
fnp-3025	671	27	and	and	CCONJ
fnp-3025	671	28	incubated	incubate	VERB
fnp-3025	671	29	for	for	ADP
fnp-3025	671	30	2	2	NUM
fnp-3025	671	31	hours	hour	NOUN
fnp-3025	671	32	at	at	ADP
fnp-3025	671	33	room	room	NOUN
fnp-3025	671	34	temperature	temperature	NOUN
fnp-3025	671	35	in	in	ADP
fnp-3025	671	36	gold	gold	NOUN
fnp-3025	671	37	-	-	PUNCT
fnp-3025	671	38	conjugated	conjugate	VERB
fnp-3025	671	39	goat	goat	PROPN
fnp-3025	671	40	anti	anti	ADJ
fnp-3025	671	41	-	-	ADJ
fnp-3025	671	42	mouse	mouse	ADJ
fnp-3025	671	43	fab	fab	NOUN
fnp-3025	671	44	’	'	PUNCT
fnp-3025	671	45	fragments	fragment	NOUN
fnp-3025	671	46	(	(	PUNCT
fnp-3025	671	47	dilution	dilution	NOUN
fnp-3025	671	48	1:100	1:100	NUM
fnp-3025	671	49	;	;	PUNCT
fnp-3025	671	50	nanogold	nanogold	PROPN
fnp-3025	671	51	[	[	X
fnp-3025	671	52	nanoprobes	nanoprobes	PROPN
fnp-3025	671	53	inc	inc	PROPN
fnp-3025	671	54	.	.	PROPN
fnp-3025	671	55	,	,	PUNCT
fnp-3025	671	56	yaphank	yaphank	PROPN
fnp-3025	671	57	,	,	PUNCT
fnp-3025	671	58	ny	ny	PROPN
fnp-3025	671	59	]	]	NOUN
fnp-3025	671	60	)	)	PUNCT
fnp-3025	671	61	.	.	PUNCT
fnp-3025	672	1	gold	gold	NOUN
fnp-3025	672	2	particles	particle	NOUN
fnp-3025	672	3	were	be	AUX
fnp-3025	672	4	silver	silver	NOUN
fnp-3025	672	5	-	-	PUNCT
fnp-3025	672	6	enhanced	enhance	VERB
fnp-3025	672	7	with	with	ADP
fnp-3025	672	8	the	the	DET
fnp-3025	672	9	hq	hq	NOUN
fnp-3025	672	10	silver	silver	NOUN
fnp-3025	672	11	kit	kit	NOUN
fnp-3025	672	12	(	(	PUNCT
fnp-3025	672	13	nanoprobes	nanoprobe	NOUN
fnp-3025	672	14	)	)	PUNCT
fnp-3025	672	15	.	.	PUNCT
fnp-3025	673	1	the	the	DET
fnp-3025	673	2	tissue	tissue	NOUN
fnp-3025	673	3	was	be	AUX
fnp-3025	673	4	then	then	ADV
fnp-3025	673	5	embedded	embed	VERB
fnp-3025	673	6	and	and	CCONJ
fnp-3025	673	7	cut	cut	VERB
fnp-3025	673	8	as	as	SCONJ
fnp-3025	673	9	described	describe	VERB
fnp-3025	673	10	above	above	ADV
fnp-3025	673	11	.	.	PUNCT
fnp-3025	674	1	thin	thin	ADJ
fnp-3025	674	2	sections	section	NOUN
fnp-3025	674	3	were	be	AUX
fnp-3025	674	4	examined	examine	VERB
fnp-3025	674	5	with	with	ADP
fnp-3025	674	6	a	a	DET
fnp-3025	674	7	zeiss	zeiss	PROPN
fnp-3025	674	8	em10	em10	PROPN
fnp-3025	674	9	-	-	PUNCT
fnp-3025	674	10	c	c	PROPN
fnp-3025	674	11	electron	electron	NOUN
fnp-3025	674	12	microscope	microscope	NOUN
fnp-3025	674	13	(	(	PUNCT
fnp-3025	674	14	oberkochen	oberkochen	PROPN
fnp-3025	674	15	,	,	PUNCT
fnp-3025	674	16	germany	germany	PROPN
fnp-3025	674	17	)	)	PUNCT
fnp-3025	674	18	and	and	CCONJ
fnp-3025	674	19	digital	digital	ADJ
fnp-3025	674	20	images	image	NOUN
fnp-3025	674	21	were	be	AUX
fnp-3025	674	22	captured	capture	VERB
fnp-3025	674	23	using	use	VERB
fnp-3025	674	24	a	a	DET
fnp-3025	674	25	dual	dual	ADJ
fnp-3025	674	26	view	view	NOUN
fnp-3025	674	27	camera	camera	NOUN
fnp-3025	674	28	(	(	PUNCT
fnp-3025	674	29	gatan	gatan	PROPN
fnp-3025	674	30	inc	inc	PROPN
fnp-3025	674	31	.	.	PROPN
fnp-3025	674	32	,	,	PUNCT
fnp-3025	674	33	pleasanton	pleasanton	PROPN
fnp-3025	674	34	,	,	PUNCT
fnp-3025	674	35	ca	ca	NOUN
fnp-3025	674	36	)	)	PUNCT
fnp-3025	674	37	.	.	PUNCT
fnp-3025	675	1	acknowledgements	acknowledgement	NOUN
fnp-3025	675	2	i	i	PRON
fnp-3025	675	3	gratefully	gratefully	ADV
fnp-3025	675	4	acknowledge	acknowledge	VERB
fnp-3025	675	5	enlightening	enlightening	ADJ
fnp-3025	675	6	discussions	discussion	NOUN
fnp-3025	675	7	with	with	ADP
fnp-3025	675	8	mathias	mathias	PROPN
fnp-3025	675	9	jucker	jucker	PROPN
fnp-3025	675	10	,	,	PUNCT
fnp-3025	675	11	dietmar	dietmar	PROPN
fnp-3025	675	12	thal	thal	PROPN
fnp-3025	675	13	,	,	PUNCT
fnp-3025	675	14	marla	marla	PROPN
fnp-3025	675	15	gearing	gearing	PROPN
fnp-3025	675	16	,	,	PUNCT
fnp-3025	675	17	harry	harry	PROPN
fnp-3025	675	18	levine	levine	PROPN
fnp-3025	675	19	,	,	PUNCT
fnp-3025	675	20	rebecca	rebecca	PROPN
fnp-3025	675	21	rosen	rosen	PROPN
fnp-3025	675	22	,	,	PUNCT
fnp-3025	675	23	amaryllis	amaryllis	PROPN
fnp-3025	675	24	cintron	cintron	PROPN
fnp-3025	675	25	,	,	PUNCT
fnp-3025	675	26	eric	eric	PROPN
fnp-3025	675	27	heuer	heuer	PROPN
fnp-3025	675	28	,	,	PUNCT
fnp-3025	675	29	david	david	PROPN
fnp-3025	675	30	lynn	lynn	PROPN
fnp-3025	675	31	,	,	PUNCT
fnp-3025	675	32	yury	yury	PROPN
fnp-3025	675	33	chernoff	chernoff	PROPN
fnp-3025	675	34	,	,	PUNCT
fnp-3025	675	35	rolf	rolf	PROPN
fnp-3025	675	36	warzok	warzok	PROPN
fnp-3025	675	37	,	,	PUNCT
fnp-3025	675	38	silke	silke	PROPN
fnp-3025	675	39	vogelgesang	vogelgesang	PROPN
fnp-3025	675	40	,	,	PUNCT
fnp-3025	675	41	sanjeev	sanjeev	PROPN
fnp-3025	675	42	gumber	gumber	PROPN
fnp-3025	675	43	,	,	PUNCT
fnp-3025	675	44	linda	linda	PROPN
fnp-3025	675	45	cork	cork	PROPN
fnp-3025	675	46	,	,	PUNCT
fnp-3025	675	47	allan	allan	PROPN
fnp-3025	675	48	levey	levey	PROPN
fnp-3025	675	49	and	and	CCONJ
fnp-3025	675	50	james	james	PROPN
fnp-3025	675	51	lah	lah	PROPN
fnp-3025	675	52	.	.	PUNCT
fnp-3025	676	1	hailian	hailian	PROPN
fnp-3025	676	2	xiao	xiao	PROPN
fnp-3025	676	3	,	,	PUNCT
fnp-3025	676	4	jean	jean	PROPN
fnp-3025	676	5	-	-	PUNCT
fnp-3025	676	6	françois	françois	PROPN
fnp-3025	676	7	paré	paré	NOUN
fnp-3025	676	8	,	,	PUNCT
fnp-3025	676	9	and	and	CCONJ
fnp-3025	676	10	jeromy	jeromy	PROPN
fnp-3025	676	11	dooyema	dooyema	PROPN
fnp-3025	676	12	provided	provide	VERB
fnp-3025	676	13	expert	expert	NOUN
fnp-3025	676	14	technical	technical	ADJ
fnp-3025	676	15	assistance	assistance	NOUN
fnp-3025	676	16	.	.	PUNCT
fnp-3025	677	1	portions	portion	NOUN
fnp-3025	677	2	of	of	ADP
fnp-3025	677	3	this	this	DET
fnp-3025	677	4	work	work	NOUN
fnp-3025	677	5	were	be	AUX
fnp-3025	677	6	supported	support	VERB
fnp-3025	677	7	by	by	ADP
fnp-3025	677	8	the	the	DET
fnp-3025	677	9	metlife	metlife	PROPN
fnp-3025	677	10	foundation	foundation	PROPN
fnp-3025	677	11	,	,	PUNCT
fnp-3025	677	12	cart	cart	NOUN
fnp-3025	677	13	foundation	foundation	PROPN
fnp-3025	677	14	,	,	PUNCT
fnp-3025	677	15	alexander	alexander	PROPN
fnp-3025	677	16	von	von	PROPN
fnp-3025	677	17	humboldt	humboldt	PROPN
fnp-3025	677	18	stiftung	stiftung	PROPN
fnp-3025	677	19	,	,	PUNCT
fnp-3025	677	20	and	and	CCONJ
fnp-3025	677	21	by	by	ADP
fnp-3025	677	22	national	national	ADJ
fnp-3025	677	23	institutes	institutes	PROPN
fnp-3025	677	24	of	of	ADP
fnp-3025	677	25	health	health	PROPN
fnp-3025	677	26	(	(	PUNCT
fnp-3025	677	27	nih	nih	NOUN
fnp-3025	677	28	)	)	PUNCT
fnp-3025	677	29	grants	grant	VERB
fnp-3025	677	30	p01	p01	NOUN
fnp-3025	677	31	ag026423	ag026423	NOUN
fnp-3025	677	32	,	,	PUNCT
fnp-3025	677	33	p50	p50	NOUN
fnp-3025	677	34	ag025688	ag025688	NOUN
fnp-3025	677	35	,	,	PUNCT
fnp-3025	677	36	r21	r21	NOUN
fnp-3025	677	37	ns077049	ns077049	PROPN
fnp-3025	677	38	,	,	PUNCT
fnp-3025	677	39	and	and	CCONJ
fnp-3025	677	40	orip	orip	NOUN
fnp-3025	677	41	/	/	SYM
fnp-3025	677	42	od	od	PROPN
fnp-3025	677	43	p51	p51	PROPN
fnp-3025	677	44	od011132	od011132	PROPN
fnp-3025	677	45	.	.	PUNCT
fnp-3025	678	1	references	reference	NOUN
fnp-3025	678	2	1	1	NUM
fnp-3025	678	3	.	.	PUNCT
fnp-3025	679	1	nelson	nelson	PROPN
fnp-3025	679	2	,	,	PUNCT
fnp-3025	679	3	p.t	p.t	PROPN
fnp-3025	679	4	.	.	PROPN
fnp-3025	679	5	,	,	PUNCT
fnp-3025	679	6	et	et	PROPN
fnp-3025	679	7	al	al	PROPN
fnp-3025	679	8	.	.	PROPN
fnp-3025	679	9	,	,	PUNCT
fnp-3025	679	10	correlation	correlation	NOUN
fnp-3025	679	11	of	of	ADP
fnp-3025	679	12	alzheimer	alzheimer	PROPN
fnp-3025	679	13	disease	disease	PROPN
fnp-3025	679	14	neuropathologic	neuropathologic	NOUN
fnp-3025	679	15	changes	change	NOUN
fnp-3025	679	16	with	with	ADP
fnp-3025	679	17	cognitive	cognitive	ADJ
fnp-3025	679	18	status	status	NOUN
fnp-3025	679	19	:	:	PUNCT
fnp-3025	679	20	a	a	DET
fnp-3025	679	21	review	review	NOUN
fnp-3025	679	22	of	of	ADP
fnp-3025	679	23	the	the	DET
fnp-3025	679	24	literature	literature	NOUN
fnp-3025	679	25	.	.	PUNCT
fnp-3025	680	1	j	j	PROPN
fnp-3025	680	2	neuropathol	neuropathol	PROPN
fnp-3025	680	3	exp	exp	PROPN
fnp-3025	680	4	neurol	neurol	NOUN
fnp-3025	680	5	,	,	PUNCT
fnp-3025	680	6	2012	2012	NUM
fnp-3025	680	7	.	.	PUNCT
fnp-3025	681	1	71(5	71(5	NUM
fnp-3025	681	2	):	):	PUNCT
fnp-3025	682	1	p.	p.	NOUN
fnp-3025	682	2	362	362	NUM
fnp-3025	682	3	-	-	SYM
fnp-3025	682	4	81	81	NUM
fnp-3025	682	5	.	.	NOUN
fnp-3025	682	6	2	2	NUM
fnp-3025	682	7	.	.	X
fnp-3025	682	8	glenner	glenner	NOUN
fnp-3025	682	9	,	,	PUNCT
fnp-3025	682	10	g.g	g.g	PROPN
fnp-3025	682	11	.	.	PROPN
fnp-3025	682	12	and	and	CCONJ
fnp-3025	682	13	c.w	c.w	PROPN
fnp-3025	682	14	.	.	PROPN
fnp-3025	682	15	wong	wong	PROPN
fnp-3025	682	16	,	,	PUNCT
fnp-3025	682	17	alzheimer	alzheimer	PROPN
fnp-3025	682	18	’s	’s	PART
fnp-3025	682	19	disease	disease	NOUN
fnp-3025	682	20	and	and	CCONJ
fnp-3025	682	21	down	down	ADP
fnp-3025	682	22	’s	’s	PART
fnp-3025	682	23	syndrome	syndrome	NOUN
fnp-3025	682	24	:	:	PUNCT
fnp-3025	682	25	sharing	sharing	NOUN
fnp-3025	682	26	of	of	ADP
fnp-3025	682	27	a	a	DET
fnp-3025	682	28	unique	unique	ADJ
fnp-3025	682	29	cerebrovascular	cerebrovascular	ADJ
fnp-3025	682	30	amyloid	amyloid	NOUN
fnp-3025	682	31	fibril	fibril	ADJ
fnp-3025	682	32	protein	protein	NOUN
fnp-3025	682	33	.	.	PUNCT
fnp-3025	683	1	biochem	biochem	PROPN
fnp-3025	683	2	biophys	biophys	PROPN
fnp-3025	683	3	res	re	NOUN
fnp-3025	683	4	commun	commun	PROPN
fnp-3025	683	5	,	,	PUNCT
fnp-3025	683	6	1984	1984	NUM
fnp-3025	683	7	.	.	PUNCT
fnp-3025	684	1	122(3	122(3	NUM
fnp-3025	684	2	):	):	PUNCT
fnp-3025	684	3	p.	p.	NOUN
fnp-3025	684	4	1131	1131	NUM
fnp-3025	684	5	-	-	SYM
fnp-3025	684	6	5	5	NUM
fnp-3025	684	7	.	.	NOUN
fnp-3025	684	8	3	3	NUM
fnp-3025	684	9	.	.	X
fnp-3025	684	10	glenner	glenner	NOUN
fnp-3025	684	11	,	,	PUNCT
fnp-3025	684	12	g.g	g.g	PROPN
fnp-3025	684	13	.	.	PROPN
fnp-3025	684	14	and	and	CCONJ
fnp-3025	684	15	c.w	c.w	PROPN
fnp-3025	684	16	.	.	PROPN
fnp-3025	684	17	wong	wong	PROPN
fnp-3025	684	18	,	,	PUNCT
fnp-3025	684	19	alzheimer	alzheimer	PROPN
fnp-3025	684	20	’s	’s	PART
fnp-3025	684	21	disease	disease	NOUN
fnp-3025	684	22	:	:	PUNCT
fnp-3025	684	23	initial	initial	ADJ
fnp-3025	684	24	report	report	NOUN
fnp-3025	684	25	of	of	ADP
fnp-3025	684	26	the	the	DET
fnp-3025	684	27	purification	purification	NOUN
fnp-3025	684	28	and	and	CCONJ
fnp-3025	684	29	characterization	characterization	NOUN
fnp-3025	684	30	of	of	ADP
fnp-3025	684	31	a	a	DET
fnp-3025	684	32	novel	novel	ADJ
fnp-3025	684	33	cerebrovascular	cerebrovascular	ADJ
fnp-3025	684	34	amyloid	amyloid	NOUN
fnp-3025	684	35	protein	protein	NOUN
fnp-3025	684	36	.	.	PUNCT
fnp-3025	685	1	biochem	biochem	PROPN
fnp-3025	685	2	biophys	biophys	PROPN
fnp-3025	685	3	res	re	NOUN
fnp-3025	685	4	commun	commun	PROPN
fnp-3025	685	5	,	,	PUNCT
fnp-3025	685	6	1984	1984	NUM
fnp-3025	685	7	.	.	PUNCT
fnp-3025	686	1	120(3	120(3	NUM
fnp-3025	686	2	):	):	PUNCT
fnp-3025	686	3	p.	p.	NOUN
fnp-3025	686	4	885	885	NUM
fnp-3025	686	5	-	-	SYM
fnp-3025	686	6	90	90	NUM
fnp-3025	686	7	.	.	PUNCT
fnp-3025	687	1	4	4	NUM
fnp-3025	687	2	.	.	X
fnp-3025	688	1	masters	master	NOUN
fnp-3025	688	2	,	,	PUNCT
fnp-3025	688	3	c.l	c.l	PROPN
fnp-3025	688	4	.	.	PROPN
fnp-3025	688	5	,	,	PUNCT
fnp-3025	688	6	et	et	PROPN
fnp-3025	688	7	al	al	PROPN
fnp-3025	688	8	.	.	PROPN
fnp-3025	688	9	,	,	PUNCT
fnp-3025	688	10	amyloid	amyloid	NOUN
fnp-3025	688	11	plaque	plaque	NOUN
fnp-3025	688	12	core	core	NOUN
fnp-3025	688	13	protein	protein	NOUN
fnp-3025	688	14	in	in	ADP
fnp-3025	688	15	alzheimer	alzheimer	NOUN
fnp-3025	688	16	disease	disease	NOUN
fnp-3025	688	17	and	and	CCONJ
fnp-3025	688	18	down	down	ADP
fnp-3025	688	19	syndrome	syndrome	NOUN
fnp-3025	688	20	.	.	PUNCT
fnp-3025	689	1	proc	proc	PROPN
fnp-3025	689	2	natl	natl	PROPN
fnp-3025	689	3	acad	acad	PROPN
fnp-3025	689	4	sci	sci	PROPN
fnp-3025	689	5	u	u	PROPN
fnp-3025	689	6	s	s	PROPN
fnp-3025	689	7	a	a	PRON
fnp-3025	689	8	,	,	PUNCT
fnp-3025	689	9	1985	1985	NUM
fnp-3025	689	10	.	.	PUNCT
fnp-3025	690	1	82(12	82(12	NUM
fnp-3025	690	2	):	):	PUNCT
fnp-3025	690	3	p.	p.	NOUN
fnp-3025	690	4	4245	4245	NUM
fnp-3025	690	5	-	-	SYM
fnp-3025	690	6	9	9	NUM
fnp-3025	690	7	.	.	NOUN
fnp-3025	690	8	5	5	NUM
fnp-3025	690	9	.	.	X
fnp-3025	691	1	masters	master	NOUN
fnp-3025	691	2	,	,	PUNCT
fnp-3025	691	3	c.l	c.l	PROPN
fnp-3025	691	4	.	.	PROPN
fnp-3025	691	5	and	and	CCONJ
fnp-3025	691	6	k.	k.	PROPN
fnp-3025	691	7	beyreuther	beyreuther	PROPN
fnp-3025	691	8	,	,	PUNCT
fnp-3025	691	9	pathways	pathway	NOUN
fnp-3025	691	10	to	to	ADP
fnp-3025	691	11	the	the	DET
fnp-3025	691	12	discovery	discovery	NOUN
fnp-3025	691	13	of	of	ADP
fnp-3025	691	14	the	the	DET
fnp-3025	691	15	abeta	abeta	PROPN
fnp-3025	691	16	amyloid	amyloid	NOUN
fnp-3025	691	17	of	of	ADP
fnp-3025	691	18	alzheimer	alzheimer	PROPN
fnp-3025	691	19	’s	’s	PART
fnp-3025	691	20	disease	disease	NOUN
fnp-3025	691	21	.	.	PUNCT
fnp-3025	692	1	j	j	PROPN
fnp-3025	692	2	alzheimers	alzheimers	PROPN
fnp-3025	692	3	dis	dis	PROPN
fnp-3025	692	4	,	,	PUNCT
fnp-3025	692	5	2006	2006	NUM
fnp-3025	692	6	.	.	PUNCT
fnp-3025	693	1	9(3	9(3	NUM
fnp-3025	693	2	suppl	suppl	PROPN
fnp-3025	693	3	):	):	PUNCT
fnp-3025	693	4	p.	p.	NOUN
fnp-3025	693	5	155	155	NUM
fnp-3025	693	6	-	-	SYM
fnp-3025	693	7	61	61	NUM
fnp-3025	693	8	.	.	PUNCT
fnp-3025	694	1	6	6	NUM
fnp-3025	694	2	.	.	X
fnp-3025	695	1	benson	benson	PROPN
fnp-3025	695	2	,	,	PUNCT
fnp-3025	695	3	m.d	m.d	PROPN
fnp-3025	695	4	.	.	PROPN
fnp-3025	695	5	,	,	PUNCT
fnp-3025	695	6	et	et	PROPN
fnp-3025	695	7	al	al	PROPN
fnp-3025	695	8	.	.	PROPN
fnp-3025	695	9	,	,	PUNCT
fnp-3025	695	10	amyloid	amyloid	NOUN
fnp-3025	695	11	nomenclature	nomenclature	NOUN
fnp-3025	695	12	2018	2018	NUM
fnp-3025	695	13	:	:	PUNCT
fnp-3025	695	14	recommendations	recommendation	NOUN
fnp-3025	695	15	by	by	ADP
fnp-3025	695	16	the	the	DET
fnp-3025	695	17	international	international	ADJ
fnp-3025	695	18	society	society	NOUN
fnp-3025	695	19	of	of	ADP
fnp-3025	695	20	amyloidosis	amyloidosis	NOUN
fnp-3025	695	21	(	(	PUNCT
fnp-3025	695	22	isa	isa	NOUN
fnp-3025	695	23	)	)	PUNCT
fnp-3025	695	24	nomenclature	nomenclature	NOUN
fnp-3025	695	25	committee	committee	NOUN
fnp-3025	695	26	.	.	PUNCT
fnp-3025	696	1	amyloid	amyloid	NOUN
fnp-3025	696	2	,	,	PUNCT
fnp-3025	696	3	2018	2018	NUM
fnp-3025	696	4	.	.	PUNCT
fnp-3025	697	1	25(4	25(4	NOUN
fnp-3025	697	2	):	):	PUNCT
fnp-3025	697	3	p.	p.	NOUN
fnp-3025	697	4	215	215	NUM
fnp-3025	697	5	-	-	SYM
fnp-3025	697	6	219	219	NUM
fnp-3025	697	7	.	.	PUNCT
fnp-3025	698	1	7	7	X
fnp-3025	698	2	.	.	X
fnp-3025	698	3	selkoe	selkoe	PROPN
fnp-3025	698	4	,	,	PUNCT
fnp-3025	698	5	d.j	d.j	PROPN
fnp-3025	698	6	.	.	PROPN
fnp-3025	698	7	,	,	PUNCT
fnp-3025	698	8	biology	biology	NOUN
fnp-3025	698	9	of	of	ADP
fnp-3025	698	10	β	β	NOUN
fnp-3025	698	11	-	-	ADJ
fnp-3025	698	12	amyloid	amyloid	ADJ
fnp-3025	698	13	precursor	precursor	NOUN
fnp-3025	698	14	protein	protein	NOUN
fnp-3025	698	15	and	and	CCONJ
fnp-3025	698	16	the	the	DET
fnp-3025	698	17	mechanism	mechanism	NOUN
fnp-3025	698	18	of	of	ADP
fnp-3025	698	19	alzheimer	alzheimer	PROPN
fnp-3025	698	20	disease	disease	PROPN
fnp-3025	698	21	,	,	PUNCT
fnp-3025	698	22	in	in	ADP
fnp-3025	698	23	alzheimer	alzheimer	PROPN
fnp-3025	698	24	disease	disease	PROPN
fnp-3025	698	25	,	,	PUNCT
fnp-3025	698	26	r.d	r.d	PROPN
fnp-3025	698	27	.	.	PROPN
fnp-3025	698	28	terry	terry	PROPN
fnp-3025	698	29	,	,	PUNCT
fnp-3025	698	30	et	et	PROPN
fnp-3025	698	31	al	al	PROPN
fnp-3025	698	32	.	.	PROPN
fnp-3025	698	33	,	,	PUNCT
fnp-3025	698	34	editors	editor	NOUN
fnp-3025	698	35	.	.	PUNCT
fnp-3025	699	1	1999	1999	NUM
fnp-3025	699	2	,	,	PUNCT
fnp-3025	699	3	lippincott	lippincott	PROPN
fnp-3025	699	4	,	,	PUNCT
fnp-3025	699	5	williams	williams	PROPN
fnp-3025	699	6	,	,	PUNCT
fnp-3025	699	7	and	and	CCONJ
fnp-3025	699	8	wilkins	wilkins	PROPN
fnp-3025	699	9	philadelphia	philadelphia	PROPN
fnp-3025	699	10	.	.	PUNCT
fnp-3025	700	1	p.	p.	NOUN
fnp-3025	700	2	293	293	NUM
fnp-3025	700	3	-	-	SYM
fnp-3025	700	4	310	310	NUM
fnp-3025	700	5	.	.	NOUN
fnp-3025	700	6	8	8	NUM
fnp-3025	700	7	.	.	X
fnp-3025	700	8	haass	haass	PROPN
fnp-3025	700	9	,	,	PUNCT
fnp-3025	700	10	c.	c.	PROPN
fnp-3025	700	11	,	,	PUNCT
fnp-3025	700	12	et	et	PROPN
fnp-3025	700	13	al	al	PROPN
fnp-3025	700	14	.	.	PROPN
fnp-3025	700	15	,	,	PUNCT
fnp-3025	700	16	trafficking	traffic	VERB
fnp-3025	700	17	and	and	CCONJ
fnp-3025	700	18	proteolytic	proteolytic	ADJ
fnp-3025	700	19	processing	processing	NOUN
fnp-3025	700	20	of	of	ADP
fnp-3025	700	21	app	app	PROPN
fnp-3025	700	22	.	.	PUNCT
fnp-3025	701	1	cold	cold	ADJ
fnp-3025	701	2	spring	spring	NOUN
fnp-3025	701	3	harb	harb	PROPN
fnp-3025	701	4	perspect	perspect	PROPN
fnp-3025	701	5	med	med	PROPN
fnp-3025	701	6	,	,	PUNCT
fnp-3025	701	7	2012	2012	NUM
fnp-3025	701	8	.	.	PUNCT
fnp-3025	702	1	2(5	2(5	NUM
fnp-3025	702	2	):	):	PUNCT
fnp-3025	702	3	p.	p.	PROPN
fnp-3025	702	4	a006270	a006270	PROPN
fnp-3025	702	5	.	.	PROPN
fnp-3025	703	1	9	9	NUM
fnp-3025	703	2	.	.	X
fnp-3025	704	1	long	long	ADJ
fnp-3025	704	2	,	,	PUNCT
fnp-3025	704	3	j.m	j.m	PROPN
fnp-3025	704	4	.	.	PROPN
fnp-3025	704	5	and	and	CCONJ
fnp-3025	704	6	d.m	d.m	PROPN
fnp-3025	704	7	.	.	PROPN
fnp-3025	704	8	holtzman	holtzman	PROPN
fnp-3025	704	9	,	,	PUNCT
fnp-3025	704	10	alzheimer	alzheimer	PROPN
fnp-3025	704	11	disease	disease	PROPN
fnp-3025	704	12	:	:	PUNCT
fnp-3025	704	13	an	an	DET
fnp-3025	704	14	update	update	NOUN
fnp-3025	704	15	on	on	ADP
fnp-3025	704	16	pathobiology	pathobiology	NOUN
fnp-3025	704	17	and	and	CCONJ
fnp-3025	704	18	treatment	treatment	NOUN
fnp-3025	704	19	strategies	strategy	NOUN
fnp-3025	704	20	.	.	PUNCT
fnp-3025	705	1	cell	cell	NOUN
fnp-3025	705	2	,	,	PUNCT
fnp-3025	705	3	2019	2019	NUM
fnp-3025	705	4	.	.	PUNCT
fnp-3025	706	1	179(2	179(2	NUM
fnp-3025	706	2	):	):	PUNCT
fnp-3025	706	3	p.	p.	NOUN
fnp-3025	706	4	312	312	NUM
fnp-3025	706	5	-	-	SYM
fnp-3025	706	6	339	339	NUM
fnp-3025	706	7	.	.	NOUN
fnp-3025	706	8	10	10	NUM
fnp-3025	706	9	.	.	PUNCT
fnp-3025	707	1	dunys	dunys	PROPN
fnp-3025	707	2	,	,	PUNCT
fnp-3025	707	3	j.	j.	PROPN
fnp-3025	707	4	,	,	PUNCT
fnp-3025	707	5	a.	a.	PROPN
fnp-3025	707	6	valverde	valverde	PROPN
fnp-3025	707	7	,	,	PUNCT
fnp-3025	707	8	and	and	CCONJ
fnp-3025	707	9	f.	f.	PROPN
fnp-3025	707	10	checler	checler	PROPN
fnp-3025	707	11	,	,	PUNCT
fnp-3025	707	12	are	be	AUX
fnp-3025	707	13	nand	nand	ADJ
fnp-3025	707	14	c	c	X
fnp-3025	707	15	-	-	PUNCT
fnp-3025	707	16	terminally	terminally	ADV
fnp-3025	707	17	truncated	truncate	VERB
fnp-3025	707	18	abeta	abeta	NOUN
fnp-3025	707	19	species	specie	NOUN
fnp-3025	707	20	key	key	ADJ
fnp-3025	707	21	pathological	pathological	ADJ
fnp-3025	707	22	triggers	trigger	NOUN
fnp-3025	707	23	in	in	ADP
fnp-3025	707	24	alzheimer	alzheimer	PROPN
fnp-3025	707	25	’s	’s	PART
fnp-3025	707	26	disease	disease	NOUN
fnp-3025	707	27	?	?	PUNCT
fnp-3025	708	1	j	j	PROPN
fnp-3025	708	2	biol	biol	PROPN
fnp-3025	708	3	chem	chem	NOUN
fnp-3025	708	4	,	,	PUNCT
fnp-3025	708	5	2018	2018	NUM
fnp-3025	708	6	.	.	PUNCT
fnp-3025	709	1	293(40	293(40	NUM
fnp-3025	709	2	):	):	PUNCT
fnp-3025	709	3	p.	p.	NOUN
fnp-3025	709	4	15419	15419	NUM
fnp-3025	709	5	-	-	SYM
fnp-3025	709	6	15428	15428	NUM
fnp-3025	709	7	.	.	PUNCT
fnp-3025	710	1	11	11	NUM
fnp-3025	710	2	.	.	PUNCT
fnp-3025	711	1	kummer	kummer	NOUN
fnp-3025	711	2	,	,	PUNCT
fnp-3025	711	3	m.p	m.p	PROPN
fnp-3025	711	4	.	.	PROPN
fnp-3025	711	5	and	and	CCONJ
fnp-3025	711	6	m.t	m.t	PROPN
fnp-3025	711	7	.	.	PROPN
fnp-3025	711	8	heneka	heneka	PROPN
fnp-3025	711	9	,	,	PUNCT
fnp-3025	711	10	truncated	truncate	VERB
fnp-3025	711	11	and	and	CCONJ
fnp-3025	711	12	modified	modify	VERB
fnp-3025	711	13	amyloid	amyloid	NOUN
fnp-3025	711	14	-	-	PUNCT
fnp-3025	711	15	beta	beta	NOUN
fnp-3025	711	16	species	specie	NOUN
fnp-3025	711	17	.	.	PUNCT
fnp-3025	712	1	alzheimers	alzheimer	NOUN
fnp-3025	712	2	res	re	VERB
fnp-3025	712	3	ther	ther	ADV
fnp-3025	712	4	,	,	PUNCT
fnp-3025	712	5	2014	2014	NUM
fnp-3025	712	6	.	.	PUNCT
fnp-3025	713	1	6(3	6(3	NUM
fnp-3025	713	2	):	):	PUNCT
fnp-3025	713	3	p.	p.	NOUN
fnp-3025	713	4	28	28	NUM
fnp-3025	713	5	.	.	PUNCT
fnp-3025	714	1	12	12	NUM
fnp-3025	714	2	.	.	PUNCT
fnp-3025	714	3	portelius	portelius	NOUN
fnp-3025	714	4	,	,	PUNCT
fnp-3025	714	5	e.	e.	PROPN
fnp-3025	714	6	,	,	PUNCT
fnp-3025	714	7	et	et	PROPN
fnp-3025	714	8	al	al	PROPN
fnp-3025	714	9	.	.	PROPN
fnp-3025	714	10	,	,	PUNCT
fnp-3025	714	11	mass	mass	NOUN
fnp-3025	714	12	spectrometric	spectrometric	ADJ
fnp-3025	714	13	characterization	characterization	NOUN
fnp-3025	714	14	of	of	ADP
fnp-3025	714	15	brain	brain	NOUN
fnp-3025	714	16	amyloid	amyloid	NOUN
fnp-3025	714	17	beta	beta	ADJ
fnp-3025	714	18	isoform	isoform	NOUN
fnp-3025	714	19	signatures	signature	NOUN
fnp-3025	714	20	in	in	ADP
fnp-3025	714	21	familial	familial	ADJ
fnp-3025	714	22	and	and	CCONJ
fnp-3025	714	23	sporadic	sporadic	ADJ
fnp-3025	714	24	alzheimer	alzheimer	PROPN
fnp-3025	714	25	’s	’s	PART
fnp-3025	714	26	disease	disease	NOUN
fnp-3025	714	27	.	.	PUNCT
fnp-3025	715	1	acta	acta	PROPN
fnp-3025	715	2	neuropathol	neuropathol	PROPN
fnp-3025	715	3	,	,	PUNCT
fnp-3025	715	4	2010	2010	NUM
fnp-3025	715	5	.	.	PUNCT
fnp-3025	716	1	120(2	120(2	NUM
fnp-3025	716	2	):	):	PUNCT
fnp-3025	717	1	p.	p.	NOUN
fnp-3025	717	2	185	185	NUM
fnp-3025	717	3	-	-	SYM
fnp-3025	717	4	93	93	NUM
fnp-3025	717	5	.	.	PUNCT
fnp-3025	718	1	13	13	NUM
fnp-3025	718	2	.	.	X
fnp-3025	718	3	portelius	portelius	NOUN
fnp-3025	718	4	,	,	PUNCT
fnp-3025	718	5	e.	e.	PROPN
fnp-3025	718	6	,	,	PUNCT
fnp-3025	718	7	et	et	PROPN
fnp-3025	718	8	al	al	PROPN
fnp-3025	718	9	.	.	PROPN
fnp-3025	718	10	,	,	PUNCT
fnp-3025	718	11	brain	brain	NOUN
fnp-3025	718	12	amyloid	amyloid	NOUN
fnp-3025	718	13	-	-	PUNCT
fnp-3025	718	14	beta	beta	ADJ
fnp-3025	718	15	fragment	fragment	NOUN
fnp-3025	718	16	signatures	signature	NOUN
fnp-3025	718	17	in	in	ADP
fnp-3025	718	18	pathological	pathological	ADJ
fnp-3025	718	19	ageing	ageing	NOUN
fnp-3025	718	20	and	and	CCONJ
fnp-3025	718	21	alzheimer	alzheimer	NOUN
fnp-3025	718	22	’s	’s	PART
fnp-3025	718	23	disease	disease	NOUN
fnp-3025	718	24	by	by	ADP
fnp-3025	718	25	hybrid	hybrid	ADJ
fnp-3025	718	26	immunoprecipitation	immunoprecipitation	NOUN
fnp-3025	718	27	mass	mass	NOUN
fnp-3025	718	28	spectrometry	spectrometry	NOUN
fnp-3025	718	29	.	.	PUNCT
fnp-3025	719	1	neurodegener	neurodegener	PROPN
fnp-3025	719	2	dis	dis	PROPN
fnp-3025	719	3	,	,	PUNCT
fnp-3025	719	4	2015	2015	NUM
fnp-3025	719	5	.	.	PUNCT
fnp-3025	720	1	15(1	15(1	NUM
fnp-3025	720	2	):	):	PUNCT
fnp-3025	720	3	p.	p.	NOUN
fnp-3025	720	4	50	50	NUM
fnp-3025	720	5	-	-	SYM
fnp-3025	720	6	7	7	NUM
fnp-3025	720	7	.	.	NOUN
fnp-3025	720	8	14	14	NUM
fnp-3025	720	9	.	.	X
fnp-3025	721	1	saido	saido	PROPN
fnp-3025	721	2	,	,	PUNCT
fnp-3025	721	3	t.c	t.c	PROPN
fnp-3025	721	4	.	.	PROPN
fnp-3025	721	5	,	,	PUNCT
fnp-3025	721	6	et	et	PROPN
fnp-3025	721	7	al	al	PROPN
fnp-3025	721	8	.	.	PROPN
fnp-3025	721	9	,	,	PUNCT
fnp-3025	721	10	aminoand	aminoand	PROPN
fnp-3025	721	11	carboxyl	carboxyl	NOUN
fnp-3025	721	12	-	-	PUNCT
fnp-3025	721	13	terminal	terminal	ADJ
fnp-3025	721	14	heterogeneity	heterogeneity	NOUN
fnp-3025	721	15	of	of	ADP
fnp-3025	721	16	beta	beta	NOUN
fnp-3025	721	17	-	-	PUNCT
fnp-3025	721	18	amyloid	amyloid	NOUN
fnp-3025	721	19	peptides	peptide	NOUN
fnp-3025	721	20	deposited	deposit	VERB
fnp-3025	721	21	in	in	ADP
fnp-3025	721	22	human	human	ADJ
fnp-3025	721	23	brain	brain	NOUN
fnp-3025	721	24	.	.	PUNCT
fnp-3025	722	1	neurosci	neurosci	PROPN
fnp-3025	722	2	lett	lett	PROPN
fnp-3025	722	3	,	,	PUNCT
fnp-3025	722	4	1996	1996	NUM
fnp-3025	722	5	.	.	PUNCT
fnp-3025	723	1	215(3	215(3	NUM
fnp-3025	723	2	):	):	PUNCT
fnp-3025	723	3	p.	p.	NOUN
fnp-3025	723	4	173	173	NUM
fnp-3025	723	5	-	-	SYM
fnp-3025	723	6	6	6	NUM
fnp-3025	723	7	.	.	NOUN
fnp-3025	723	8	15	15	NUM
fnp-3025	723	9	.	.	PUNCT
fnp-3025	724	1	takami	takami	NOUN
fnp-3025	724	2	,	,	PUNCT
fnp-3025	724	3	m.	m.	NOUN
fnp-3025	724	4	,	,	PUNCT
fnp-3025	724	5	et	et	PROPN
fnp-3025	724	6	al	al	PROPN
fnp-3025	724	7	.	.	PROPN
fnp-3025	724	8	,	,	PUNCT
fnp-3025	724	9	gamma	gamma	NOUN
fnp-3025	724	10	-	-	PUNCT
fnp-3025	724	11	secretase	secretase	NOUN
fnp-3025	724	12	:	:	PUNCT
fnp-3025	724	13	successive	successive	ADJ
fnp-3025	724	14	tripeptide	tripeptide	ADV
fnp-3025	724	15	and	and	CCONJ
fnp-3025	724	16	tetrapeptide	tetrapeptide	ADJ
fnp-3025	724	17	release	release	NOUN
fnp-3025	724	18	from	from	ADP
fnp-3025	724	19	the	the	DET
fnp-3025	724	20	transmembrane	transmembrane	ADJ
fnp-3025	724	21	domain	domain	NOUN
fnp-3025	724	22	of	of	ADP
fnp-3025	724	23	beta	beta	NOUN
fnp-3025	724	24	-	-	PUNCT
fnp-3025	724	25	carboxyl	carboxyl	NOUN
fnp-3025	724	26	terminal	terminal	NOUN
fnp-3025	724	27	fragment	fragment	NOUN
fnp-3025	724	28	.	.	PUNCT
fnp-3025	725	1	j	j	PROPN
fnp-3025	725	2	neurosci	neurosci	PROPN
fnp-3025	725	3	,	,	PUNCT
fnp-3025	725	4	2009	2009	NUM
fnp-3025	725	5	.	.	PUNCT
fnp-3025	726	1	29(41	29(41	NUM
fnp-3025	726	2	):	):	PUNCT
fnp-3025	726	3	p.	p.	NOUN
fnp-3025	726	4	13042	13042	NUM
fnp-3025	726	5	-	-	SYM
fnp-3025	726	6	52	52	NUM
fnp-3025	726	7	.	.	PUNCT
fnp-3025	727	1	16	16	NUM
fnp-3025	727	2	.	.	PUNCT
fnp-3025	728	1	tekirian	tekirian	ADJ
fnp-3025	728	2	,	,	PUNCT
fnp-3025	728	3	t.l	t.l	PROPN
fnp-3025	728	4	.	.	PROPN
fnp-3025	728	5	,	,	PUNCT
fnp-3025	728	6	et	et	PROPN
fnp-3025	728	7	al	al	PROPN
fnp-3025	728	8	.	.	PROPN
fnp-3025	728	9	,	,	PUNCT
fnp-3025	728	10	n	n	CCONJ
fnp-3025	728	11	-	-	PUNCT
fnp-3025	728	12	terminal	terminal	ADJ
fnp-3025	728	13	heterogeneity	heterogeneity	NOUN
fnp-3025	728	14	of	of	ADP
fnp-3025	728	15	parenchymal	parenchymal	ADJ
fnp-3025	728	16	and	and	CCONJ
fnp-3025	728	17	cerebrovascular	cerebrovascular	ADJ
fnp-3025	728	18	abeta	abeta	NOUN
fnp-3025	728	19	deposits	deposit	NOUN
fnp-3025	728	20	.	.	PUNCT
fnp-3025	729	1	j	j	PROPN
fnp-3025	729	2	neuropathol	neuropathol	PROPN
fnp-3025	729	3	exp	exp	PROPN
fnp-3025	729	4	neurol	neurol	PROPN
fnp-3025	729	5	,	,	PUNCT
fnp-3025	729	6	1998	1998	NUM
fnp-3025	729	7	.	.	PUNCT
fnp-3025	730	1	57(1	57(1	NUM
fnp-3025	730	2	):	):	PUNCT
fnp-3025	731	1	p.	p.	NOUN
fnp-3025	731	2	76	76	NUM
fnp-3025	731	3	-	-	SYM
fnp-3025	731	4	94	94	NUM
fnp-3025	731	5	.	.	PUNCT
fnp-3025	731	6	17	17	NUM
fnp-3025	731	7	.	.	PUNCT
fnp-3025	732	1	moro	moro	PROPN
fnp-3025	732	2	,	,	PUNCT
fnp-3025	732	3	m.l	m.l	PROPN
fnp-3025	732	4	.	.	PROPN
fnp-3025	732	5	,	,	PUNCT
fnp-3025	732	6	et	et	PROPN
fnp-3025	732	7	al	al	PROPN
fnp-3025	732	8	.	.	PROPN
fnp-3025	732	9	,	,	PUNCT
fnp-3025	732	10	pyroglutamate	pyroglutamate	NOUN
fnp-3025	732	11	and	and	CCONJ
fnp-3025	732	12	isoaspartate	isoaspartate	ADJ
fnp-3025	732	13	modified	modify	VERB
fnp-3025	732	14	amyloid	amyloid	NOUN
fnp-3025	732	15	-	-	PUNCT
fnp-3025	732	16	beta	beta	NOUN
fnp-3025	732	17	in	in	ADP
fnp-3025	732	18	ageing	ageing	NOUN
fnp-3025	732	19	and	and	CCONJ
fnp-3025	732	20	alzheimer	alzheimer	NOUN
fnp-3025	732	21	’s	’s	PART
fnp-3025	732	22	disease	disease	NOUN
fnp-3025	732	23	.	.	PUNCT
fnp-3025	733	1	acta	acta	PROPN
fnp-3025	733	2	neuropathol	neuropathol	PROPN
fnp-3025	733	3	commun	commun	PROPN
fnp-3025	733	4	,	,	PUNCT
fnp-3025	733	5	2018	2018	NUM
fnp-3025	733	6	.	.	PUNCT
fnp-3025	734	1	6(1	6(1	NUM
fnp-3025	734	2	):	):	PUNCT
fnp-3025	735	1	p.	p.	NOUN
fnp-3025	735	2	3	3	NUM
fnp-3025	735	3	.	.	PROPN
fnp-3025	735	4	18	18	NUM
fnp-3025	735	5	.	.	PUNCT
fnp-3025	736	1	schaffert	schaffert	PROPN
fnp-3025	736	2	,	,	PUNCT
fnp-3025	736	3	l.n	l.n	PROPN
fnp-3025	736	4	.	.	PROPN
fnp-3025	736	5	and	and	CCONJ
fnp-3025	736	6	w.g	w.g	PROPN
fnp-3025	736	7	.	.	PROPN
fnp-3025	736	8	carter	carter	PROPN
fnp-3025	736	9	,	,	PUNCT
fnp-3025	736	10	do	do	VERB
fnp-3025	736	11	post	post	ADJ
fnp-3025	736	12	-	-	ADJ
fnp-3025	736	13	translational	translational	ADJ
fnp-3025	736	14	modifications	modification	NOUN
fnp-3025	736	15	influence	influence	NOUN
fnp-3025	736	16	protein	protein	NOUN
fnp-3025	736	17	aggregation	aggregation	NOUN
fnp-3025	736	18	in	in	ADP
fnp-3025	736	19	neurodegenerative	neurodegenerative	ADJ
fnp-3025	736	20	diseases	disease	NOUN
fnp-3025	736	21	:	:	PUNCT
fnp-3025	736	22	a	a	DET
fnp-3025	736	23	systematic	systematic	ADJ
fnp-3025	736	24	review	review	NOUN
fnp-3025	736	25	.	.	PUNCT
fnp-3025	737	1	brain	brain	PROPN
fnp-3025	737	2	sci	sci	PROPN
fnp-3025	737	3	,	,	PUNCT
fnp-3025	737	4	2020	2020	NUM
fnp-3025	737	5	.	.	PUNCT
fnp-3025	738	1	10(4	10(4	NUM
fnp-3025	738	2	):	):	PUNCT
fnp-3025	738	3	p.	p.	NOUN
fnp-3025	738	4	232	232	NUM
fnp-3025	738	5	.	.	PUNCT
fnp-3025	739	1	19	19	NUM
fnp-3025	739	2	.	.	X
fnp-3025	739	3	thal	thal	PROPN
fnp-3025	739	4	,	,	PUNCT
fnp-3025	739	5	d.r	d.r	PROPN
fnp-3025	739	6	.	.	PROPN
fnp-3025	739	7	,	,	PUNCT
fnp-3025	739	8	et	et	PROPN
fnp-3025	739	9	al	al	PROPN
fnp-3025	739	10	.	.	PROPN
fnp-3025	739	11	,	,	PUNCT
fnp-3025	739	12	neuropathology	neuropathology	NOUN
fnp-3025	739	13	and	and	CCONJ
fnp-3025	739	14	biochemistry	biochemistry	NOUN
fnp-3025	739	15	of	of	ADP
fnp-3025	739	16	abeta	abeta	PROPN
fnp-3025	739	17	and	and	CCONJ
fnp-3025	739	18	its	its	PRON
fnp-3025	739	19	aggregates	aggregate	NOUN
fnp-3025	739	20	in	in	ADP
fnp-3025	739	21	alzheimer	alzheimer	PROPN
fnp-3025	739	22	’s	’s	PART
fnp-3025	739	23	disease	disease	NOUN
fnp-3025	739	24	.	.	PUNCT
fnp-3025	740	1	acta	acta	PROPN
fnp-3025	740	2	neuropathol	neuropathol	PROPN
fnp-3025	740	3	,	,	PUNCT
fnp-3025	740	4	2015	2015	NUM
fnp-3025	740	5	.	.	PUNCT
fnp-3025	741	1	129(2	129(2	NUM
fnp-3025	741	2	):	):	PUNCT
fnp-3025	741	3	p.	p.	NOUN
fnp-3025	741	4	167	167	NUM
fnp-3025	741	5	-	-	SYM
fnp-3025	741	6	82	82	NUM
fnp-3025	741	7	.	.	NOUN
fnp-3025	741	8	20	20	NUM
fnp-3025	741	9	.	.	PUNCT
fnp-3025	742	1	ke	ke	PROPN
fnp-3025	742	2	,	,	PUNCT
fnp-3025	742	3	p.c	p.c	PROPN
fnp-3025	742	4	.	.	PROPN
fnp-3025	742	5	,	,	PUNCT
fnp-3025	742	6	et	et	PROPN
fnp-3025	742	7	al	al	PROPN
fnp-3025	742	8	.	.	PROPN
fnp-3025	742	9	,	,	PUNCT
fnp-3025	742	10	half	half	DET
fnp-3025	742	11	a	a	DET
fnp-3025	742	12	century	century	NOUN
fnp-3025	742	13	of	of	ADP
fnp-3025	742	14	amyloids	amyloid	NOUN
fnp-3025	742	15	:	:	PUNCT
fnp-3025	742	16	past	past	ADJ
fnp-3025	742	17	,	,	PUNCT
fnp-3025	742	18	present	present	ADJ
fnp-3025	742	19	and	and	CCONJ
fnp-3025	742	20	future	future	ADJ
fnp-3025	742	21	.	.	PUNCT
fnp-3025	743	1	chem	chem	NOUN
fnp-3025	743	2	soc	soc	PROPN
fnp-3025	743	3	rev	rev	VERB
fnp-3025	743	4	,	,	PUNCT
fnp-3025	743	5	2020	2020	NUM
fnp-3025	743	6	.	.	PUNCT
fnp-3025	744	1	49(15	49(15	NUM
fnp-3025	744	2	):	):	PUNCT
fnp-3025	744	3	p.	p.	NOUN
fnp-3025	744	4	5473	5473	NUM
fnp-3025	744	5	-	-	SYM
fnp-3025	744	6	5509	5509	NUM
fnp-3025	744	7	.	.	PUNCT
fnp-3025	745	1	21	21	NUM
fnp-3025	745	2	.	.	PUNCT
fnp-3025	745	3	greenberg	greenberg	PROPN
fnp-3025	745	4	,	,	PUNCT
fnp-3025	745	5	s.m	s.m	PROPN
fnp-3025	745	6	.	.	PROPN
fnp-3025	745	7	,	,	PUNCT
fnp-3025	745	8	et	et	PROPN
fnp-3025	745	9	al	al	PROPN
fnp-3025	745	10	.	.	PROPN
fnp-3025	745	11	,	,	PUNCT
fnp-3025	745	12	cerebral	cerebral	ADJ
fnp-3025	745	13	amyloid	amyloid	NOUN
fnp-3025	745	14	angiopathy	angiopathy	ADJ
fnp-3025	745	15	and	and	CCONJ
fnp-3025	745	16	alzheimer	alzheimer	NOUN
fnp-3025	745	17	disease	disease	NOUN
fnp-3025	745	18	one	one	NUM
fnp-3025	745	19	peptide	peptide	NOUN
fnp-3025	745	20	,	,	PUNCT
fnp-3025	745	21	two	two	NUM
fnp-3025	745	22	pathways	pathway	NOUN
fnp-3025	745	23	.	.	PUNCT
fnp-3025	746	1	nat	nat	PROPN
fnp-3025	746	2	rev	rev	PROPN
fnp-3025	746	3	neurol	neurol	PROPN
fnp-3025	746	4	,	,	PUNCT
fnp-3025	746	5	2020	2020	NUM
fnp-3025	746	6	.	.	PUNCT
fnp-3025	747	1	16(1	16(1	NUM
fnp-3025	747	2	):	):	PUNCT
fnp-3025	748	1	p.	p.	NOUN
fnp-3025	748	2	30	30	NUM
fnp-3025	748	3	-	-	SYM
fnp-3025	748	4	42	42	NUM
fnp-3025	748	5	.	.	PUNCT
fnp-3025	749	1	22	22	NUM
fnp-3025	749	2	.	.	PUNCT
fnp-3025	750	1	holtzman	holtzman	PROPN
fnp-3025	750	2	,	,	PUNCT
fnp-3025	750	3	d.m	d.m	PROPN
fnp-3025	750	4	.	.	PROPN
fnp-3025	750	5	,	,	PUNCT
fnp-3025	750	6	j.c	j.c	PROPN
fnp-3025	750	7	.	.	PROPN
fnp-3025	750	8	morris	morris	PROPN
fnp-3025	750	9	,	,	PUNCT
fnp-3025	750	10	and	and	CCONJ
fnp-3025	750	11	a.m.	a.m.	PROPN
fnp-3025	750	12	goate	goate	PROPN
fnp-3025	750	13	,	,	PUNCT
fnp-3025	750	14	alzheimer	alzheimer	PROPN
fnp-3025	750	15	’s	’s	PART
fnp-3025	750	16	disease	disease	NOUN
fnp-3025	750	17	:	:	PUNCT
fnp-3025	750	18	the	the	DET
fnp-3025	750	19	challenge	challenge	NOUN
fnp-3025	750	20	of	of	ADP
fnp-3025	750	21	the	the	DET
fnp-3025	750	22	second	second	ADJ
fnp-3025	750	23	century	century	NOUN
fnp-3025	750	24	.	.	PUNCT
fnp-3025	751	1	sci	sci	PROPN
fnp-3025	751	2	transl	transl	PROPN
fnp-3025	751	3	med	med	PROPN
fnp-3025	751	4	,	,	PUNCT
fnp-3025	751	5	2011	2011	NUM
fnp-3025	751	6	.	.	PUNCT
fnp-3025	752	1	3(77	3(77	NUM
fnp-3025	752	2	):	):	PUNCT
fnp-3025	753	1	p.	p.	NOUN
fnp-3025	753	2	77sr1	77sr1	NUM
fnp-3025	753	3	.	.	PUNCT
fnp-3025	753	4	23	23	NUM
fnp-3025	753	5	.	.	PUNCT
fnp-3025	754	1	roher	roher	PROPN
fnp-3025	754	2	,	,	PUNCT
fnp-3025	754	3	a.e	a.e	PROPN
fnp-3025	754	4	.	.	PROPN
fnp-3025	754	5	,	,	PUNCT
fnp-3025	754	6	et	et	PROPN
fnp-3025	754	7	al	al	PROPN
fnp-3025	754	8	.	.	PROPN
fnp-3025	754	9	,	,	PUNCT
fnp-3025	754	10	beta	beta	NOUN
fnp-3025	754	11	-	-	PUNCT
fnp-3025	754	12	amyloid-(1	amyloid-(1	NOUN
fnp-3025	754	13	-	-	PUNCT
fnp-3025	754	14	42	42	NUM
fnp-3025	754	15	)	)	PUNCT
fnp-3025	754	16	is	be	AUX
fnp-3025	754	17	a	a	DET
fnp-3025	754	18	major	major	ADJ
fnp-3025	754	19	component	component	NOUN
fnp-3025	754	20	of	of	ADP
fnp-3025	754	21	cerebrovascular	cerebrovascular	ADJ
fnp-3025	754	22	amyloid	amyloid	NOUN
fnp-3025	754	23	deposits	deposit	NOUN
fnp-3025	754	24	:	:	PUNCT
fnp-3025	754	25	implications	implication	NOUN
fnp-3025	754	26	for	for	ADP
fnp-3025	754	27	the	the	DET
fnp-3025	754	28	pathology	pathology	NOUN
fnp-3025	754	29	of	of	ADP
fnp-3025	754	30	alzheimer	alzheimer	PROPN
fnp-3025	754	31	disease	disease	PROPN
fnp-3025	754	32	.	.	PUNCT
fnp-3025	755	1	proc	proc	PROPN
fnp-3025	755	2	natl	natl	PROPN
fnp-3025	755	3	acad	acad	PROPN
fnp-3025	755	4	sci	sci	PROPN
fnp-3025	755	5	u	u	PROPN
fnp-3025	755	6	s	s	PROPN
fnp-3025	755	7	a	a	PRON
fnp-3025	755	8	,	,	PUNCT
fnp-3025	755	9	1993	1993	NUM
fnp-3025	755	10	.	.	PUNCT
fnp-3025	756	1	90(22	90(22	NOUN
fnp-3025	756	2	):	):	PUNCT
fnp-3025	756	3	p.	p.	NOUN
fnp-3025	756	4	10836	10836	NUM
fnp-3025	756	5	-	-	SYM
fnp-3025	756	6	40	40	NUM
fnp-3025	756	7	.	.	PUNCT
fnp-3025	757	1	24	24	NUM
fnp-3025	757	2	.	.	PUNCT
fnp-3025	757	3	attems	attems	PROPN
fnp-3025	757	4	,	,	PUNCT
fnp-3025	757	5	j.	j.	PROPN
fnp-3025	757	6	,	,	PUNCT
fnp-3025	757	7	f.	f.	PROPN
fnp-3025	757	8	lintner	lintner	PROPN
fnp-3025	757	9	,	,	PUNCT
fnp-3025	757	10	and	and	CCONJ
fnp-3025	757	11	k.a	k.a	PROPN
fnp-3025	757	12	.	.	PUNCT
fnp-3025	758	1	jellinger	jellinger	PROPN
fnp-3025	758	2	,	,	PUNCT
fnp-3025	758	3	amyloid	amyloid	NOUN
fnp-3025	758	4	beta	beta	NOUN
fnp-3025	758	5	peptide	peptide	NOUN
fnp-3025	758	6	1	1	NUM
fnp-3025	758	7	-	-	SYM
fnp-3025	758	8	42	42	NUM
fnp-3025	758	9	highly	highly	ADV
fnp-3025	758	10	correlates	correlate	VERB
fnp-3025	758	11	with	with	ADP
fnp-3025	758	12	capillary	capillary	ADJ
fnp-3025	758	13	cerebral	cerebral	ADJ
fnp-3025	758	14	amyloid	amyloid	NOUN
fnp-3025	758	15	angiopathy	angiopathy	ADJ
fnp-3025	758	16	and	and	CCONJ
fnp-3025	758	17	alzheimer	alzheimer	PROPN
fnp-3025	758	18	disease	disease	PROPN
fnp-3025	758	19	pathology	pathology	PROPN
fnp-3025	758	20	.	.	PUNCT
fnp-3025	759	1	acta	acta	PROPN
fnp-3025	759	2	neuropathol	neuropathol	PROPN
fnp-3025	759	3	,	,	PUNCT
fnp-3025	759	4	2004	2004	NUM
fnp-3025	759	5	.	.	PUNCT
fnp-3025	760	1	107(4	107(4	NUM
fnp-3025	760	2	):	):	PUNCT
fnp-3025	760	3	p.	p.	NOUN
fnp-3025	760	4	283	283	NUM
fnp-3025	760	5	-	-	SYM
fnp-3025	760	6	91	91	NUM
fnp-3025	760	7	.	.	PUNCT
fnp-3025	761	1	25	25	NUM
fnp-3025	761	2	.	.	PUNCT
fnp-3025	762	1	richard	richard	PROPN
fnp-3025	762	2	,	,	PUNCT
fnp-3025	762	3	e.	e.	PROPN
fnp-3025	762	4	,	,	PUNCT
fnp-3025	762	5	et	et	PROPN
fnp-3025	762	6	al	al	PROPN
fnp-3025	762	7	.	.	PROPN
fnp-3025	762	8	,	,	PUNCT
fnp-3025	762	9	characteristics	characteristic	NOUN
fnp-3025	762	10	of	of	ADP
fnp-3025	762	11	dyshoric	dyshoric	ADJ
fnp-3025	762	12	capillary	capillary	ADJ
fnp-3025	762	13	cerebral	cerebral	ADJ
fnp-3025	762	14	amyloid	amyloid	NOUN
fnp-3025	762	15	angiopathy	angiopathy	NOUN
fnp-3025	762	16	.	.	PUNCT
fnp-3025	763	1	j	j	PROPN
fnp-3025	763	2	neuropathol	neuropathol	PROPN
fnp-3025	763	3	exp	exp	PROPN
fnp-3025	763	4	neurol	neurol	PROPN
fnp-3025	763	5	,	,	PUNCT
fnp-3025	763	6	2010	2010	NUM
fnp-3025	763	7	.	.	PUNCT
fnp-3025	764	1	69(11	69(11	NUM
fnp-3025	764	2	):	):	PUNCT
fnp-3025	764	3	p.	p.	NOUN
fnp-3025	764	4	1158	1158	NUM
fnp-3025	764	5	-	-	SYM
fnp-3025	764	6	67	67	NUM
fnp-3025	764	7	.	.	PUNCT
fnp-3025	765	1	26	26	NUM
fnp-3025	765	2	.	.	PUNCT
fnp-3025	765	3	attems	attems	PROPN
fnp-3025	765	4	,	,	PUNCT
fnp-3025	765	5	j.	j.	PROPN
fnp-3025	765	6	,	,	PUNCT
fnp-3025	765	7	et	et	PROPN
fnp-3025	765	8	al	al	PROPN
fnp-3025	765	9	.	.	PROPN
fnp-3025	765	10	,	,	PUNCT
fnp-3025	765	11	capillary	capillary	ADJ
fnp-3025	765	12	caa	caa	NOUN
fnp-3025	765	13	and	and	CCONJ
fnp-3025	765	14	perivascular	perivascular	ADJ
fnp-3025	765	15	abeta	abeta	NOUN
fnp-3025	765	16	-	-	PUNCT
fnp-3025	765	17	deposition	deposition	NOUN
fnp-3025	765	18	:	:	PUNCT
fnp-3025	765	19	two	two	NUM
fnp-3025	765	20	distinct	distinct	ADJ
fnp-3025	765	21	features	feature	NOUN
fnp-3025	765	22	of	of	ADP
fnp-3025	765	23	alzheimer	alzheimer	PROPN
fnp-3025	765	24	’s	’s	PART
fnp-3025	765	25	disease	disease	NOUN
fnp-3025	765	26	pathology	pathology	PROPN
fnp-3025	765	27	.	.	PUNCT
fnp-3025	766	1	j	j	PROPN
fnp-3025	766	2	neurol	neurol	PROPN
fnp-3025	766	3	sci	sci	PROPN
fnp-3025	766	4	,	,	PUNCT
fnp-3025	766	5	2010	2010	NUM
fnp-3025	766	6	.	.	PUNCT
fnp-3025	767	1	299(1	299(1	NUM
fnp-3025	767	2	-	-	SYM
fnp-3025	767	3	2	2	NUM
fnp-3025	767	4	):	):	PUNCT
fnp-3025	767	5	p.	p.	NOUN
fnp-3025	767	6	155	155	NUM
fnp-3025	767	7	-	-	SYM
fnp-3025	767	8	62	62	NUM
fnp-3025	767	9	.	.	PUNCT
fnp-3025	768	1	27	27	NUM
fnp-3025	768	2	.	.	PUNCT
fnp-3025	769	1	catalano	catalano	PROPN
fnp-3025	769	2	,	,	PUNCT
fnp-3025	769	3	s.m	s.m	PROPN
fnp-3025	769	4	.	.	PROPN
fnp-3025	769	5	,	,	PUNCT
fnp-3025	769	6	et	et	PROPN
fnp-3025	769	7	al	al	PROPN
fnp-3025	769	8	.	.	PROPN
fnp-3025	769	9	,	,	PUNCT
fnp-3025	769	10	the	the	DET
fnp-3025	769	11	role	role	NOUN
fnp-3025	769	12	of	of	ADP
fnp-3025	769	13	amyloid	amyloid	NOUN
fnp-3025	769	14	-	-	PUNCT
fnp-3025	769	15	beta	beta	NOUN
fnp-3025	769	16	derived	derive	VERB
fnp-3025	769	17	diffusible	diffusible	ADJ
fnp-3025	769	18	ligands	ligand	NOUN
fnp-3025	769	19	(	(	PUNCT
fnp-3025	769	20	addls	addls	PROPN
fnp-3025	769	21	)	)	PUNCT
fnp-3025	769	22	in	in	ADP
fnp-3025	769	23	alzheimer	alzheimer	PROPN
fnp-3025	769	24	’s	’s	PART
fnp-3025	769	25	disease	disease	NOUN
fnp-3025	769	26	.	.	PUNCT
fnp-3025	770	1	curr	curr	PROPN
fnp-3025	770	2	top	top	ADJ
fnp-3025	770	3	med	med	PROPN
fnp-3025	770	4	chem	chem	NOUN
fnp-3025	770	5	,	,	PUNCT
fnp-3025	770	6	2006	2006	NUM
fnp-3025	770	7	.	.	PUNCT
fnp-3025	771	1	6(6	6(6	NUM
fnp-3025	771	2	):	):	PUNCT
fnp-3025	771	3	p.	p.	NOUN
fnp-3025	771	4	597	597	NUM
fnp-3025	771	5	-	-	SYM
fnp-3025	771	6	608	608	NUM
fnp-3025	771	7	.	.	PUNCT
fnp-3025	771	8	28	28	NUM
fnp-3025	771	9	.	.	PUNCT
fnp-3025	772	1	kuo	kuo	PROPN
fnp-3025	772	2	,	,	PUNCT
fnp-3025	772	3	y.m	y.m	PROPN
fnp-3025	772	4	.	.	PROPN
fnp-3025	772	5	,	,	PUNCT
fnp-3025	772	6	et	et	PROPN
fnp-3025	772	7	al	al	PROPN
fnp-3025	772	8	.	.	PROPN
fnp-3025	772	9	,	,	PUNCT
fnp-3025	772	10	water	water	NOUN
fnp-3025	772	11	-	-	PUNCT
fnp-3025	772	12	soluble	soluble	ADJ
fnp-3025	772	13	abeta	abeta	NOUN
fnp-3025	772	14	(	(	PUNCT
fnp-3025	772	15	n-40	n-40	PROPN
fnp-3025	772	16	,	,	PUNCT
fnp-3025	772	17	n-42	n-42	NUM
fnp-3025	772	18	)	)	PUNCT
fnp-3025	772	19	oligomers	oligomer	NOUN
fnp-3025	772	20	in	in	ADP
fnp-3025	772	21	normal	normal	ADJ
fnp-3025	772	22	and	and	CCONJ
fnp-3025	772	23	alzheimer	alzheimer	NOUN
fnp-3025	772	24	disease	disease	NOUN
fnp-3025	772	25	brains	brain	NOUN
fnp-3025	772	26	.	.	PUNCT
fnp-3025	773	1	j	j	PROPN
fnp-3025	773	2	biol	biol	PROPN
fnp-3025	773	3	chem	chem	NOUN
fnp-3025	773	4	,	,	PUNCT
fnp-3025	773	5	1996	1996	NUM
fnp-3025	773	6	.	.	PUNCT
fnp-3025	774	1	271(8	271(8	NUM
fnp-3025	774	2	):	):	PUNCT
fnp-3025	774	3	p.	p.	NOUN
fnp-3025	774	4	4077	4077	NUM
fnp-3025	774	5	-	-	SYM
fnp-3025	774	6	81	81	NUM
fnp-3025	774	7	.	.	PUNCT
fnp-3025	774	8	29	29	NUM
fnp-3025	774	9	.	.	X
fnp-3025	775	1	cline	cline	PROPN
fnp-3025	775	2	,	,	PUNCT
fnp-3025	775	3	e.n	e.n	PROPN
fnp-3025	775	4	.	.	PROPN
fnp-3025	775	5	,	,	PUNCT
fnp-3025	775	6	et	et	PROPN
fnp-3025	775	7	al	al	PROPN
fnp-3025	775	8	.	.	PROPN
fnp-3025	775	9	,	,	PUNCT
fnp-3025	775	10	the	the	DET
fnp-3025	775	11	amyloid	amyloid	NOUN
fnp-3025	775	12	-	-	PUNCT
fnp-3025	775	13	beta	beta	ADJ
fnp-3025	775	14	oligomer	oligomer	ADJ
fnp-3025	775	15	hypothesis	hypothesis	NOUN
fnp-3025	775	16	:	:	PUNCT
fnp-3025	775	17	beginning	begin	VERB
fnp-3025	775	18	of	of	ADP
fnp-3025	775	19	the	the	DET
fnp-3025	775	20	third	third	ADJ
fnp-3025	775	21	decade	decade	NOUN
fnp-3025	775	22	.	.	PUNCT
fnp-3025	776	1	j	j	PROPN
fnp-3025	776	2	alzheimers	alzheimers	PROPN
fnp-3025	776	3	dis	dis	PROPN
fnp-3025	776	4	,	,	PUNCT
fnp-3025	776	5	2018	2018	NUM
fnp-3025	776	6	.	.	PUNCT
fnp-3025	777	1	64(s1	64(s1	X
fnp-3025	777	2	):	):	PUNCT
fnp-3025	777	3	p.	p.	NOUN
fnp-3025	777	4	s567	s567	PROPN
fnp-3025	777	5	-	-	PUNCT
fnp-3025	777	6	s610	s610	PROPN
fnp-3025	777	7	.	.	PUNCT
fnp-3025	777	8	30	30	NUM
fnp-3025	777	9	.	.	PUNCT
fnp-3025	778	1	ferreira	ferreira	PROPN
fnp-3025	778	2	,	,	PUNCT
fnp-3025	778	3	s.t	s.t	PROPN
fnp-3025	778	4	.	.	PROPN
fnp-3025	778	5	,	,	PUNCT
fnp-3025	778	6	et	et	PROPN
fnp-3025	778	7	al	al	PROPN
fnp-3025	778	8	.	.	PROPN
fnp-3025	778	9	,	,	PUNCT
fnp-3025	778	10	soluble	soluble	ADJ
fnp-3025	778	11	amyloid	amyloid	NOUN
fnp-3025	778	12	-	-	PUNCT
fnp-3025	778	13	beta	beta	NOUN
fnp-3025	778	14	oligomers	oligomer	NOUN
fnp-3025	778	15	as	as	ADP
fnp-3025	778	16	synaptotoxins	synaptotoxin	NOUN
fnp-3025	778	17	leading	lead	VERB
fnp-3025	778	18	to	to	ADP
fnp-3025	778	19	cognitive	cognitive	ADJ
fnp-3025	778	20	impairment	impairment	NOUN
fnp-3025	778	21	in	in	ADP
fnp-3025	778	22	alzheimer	alzheimer	PROPN
fnp-3025	778	23	’s	’s	PART
fnp-3025	778	24	disease	disease	NOUN
fnp-3025	778	25	.	.	PUNCT
fnp-3025	779	1	front	front	ADJ
fnp-3025	779	2	cell	cell	NOUN
fnp-3025	779	3	neurosci	neurosci	NOUN
fnp-3025	779	4	,	,	PUNCT
fnp-3025	779	5	2015	2015	NUM
fnp-3025	779	6	.	.	PUNCT
fnp-3025	780	1	9	9	NUM
fnp-3025	780	2	:	:	PUNCT
fnp-3025	780	3	p.	p.	NOUN
fnp-3025	780	4	191	191	NUM
fnp-3025	780	5	.	.	PUNCT
fnp-3025	781	1	31	31	NUM
fnp-3025	781	2	.	.	PUNCT
fnp-3025	782	1	haass	haass	PROPN
fnp-3025	782	2	,	,	PUNCT
fnp-3025	782	3	c.	c.	PROPN
fnp-3025	782	4	and	and	CCONJ
fnp-3025	782	5	d.j	d.j	PROPN
fnp-3025	782	6	.	.	PROPN
fnp-3025	782	7	selkoe	selkoe	PROPN
fnp-3025	782	8	,	,	PUNCT
fnp-3025	782	9	soluble	soluble	ADJ
fnp-3025	782	10	protein	protein	NOUN
fnp-3025	782	11	oligomers	oligomer	NOUN
fnp-3025	782	12	in	in	ADP
fnp-3025	782	13	neurodegeneration	neurodegeneration	NOUN
fnp-3025	782	14	:	:	PUNCT
fnp-3025	782	15	lessons	lesson	NOUN
fnp-3025	782	16	from	from	ADP
fnp-3025	782	17	the	the	DET
fnp-3025	782	18	alzheimer	alzheimer	PROPN
fnp-3025	782	19	’s	’s	PART
fnp-3025	782	20	amyloid	amyloid	NOUN
fnp-3025	782	21	beta	beta	NOUN
fnp-3025	782	22	-	-	PUNCT
fnp-3025	782	23	peptide	peptide	NOUN
fnp-3025	782	24	.	.	PUNCT
fnp-3025	783	1	nat	nat	PROPN
fnp-3025	783	2	rev	rev	VERB
fnp-3025	783	3	mol	mol	ADP
fnp-3025	783	4	cell	cell	NOUN
fnp-3025	783	5	biol	biol	NOUN
fnp-3025	783	6	,	,	PUNCT
fnp-3025	783	7	2007	2007	NUM
fnp-3025	783	8	.	.	PUNCT
fnp-3025	784	1	8(2	8(2	NUM
fnp-3025	784	2	):	):	PUNCT
fnp-3025	785	1	p.	p.	NOUN
fnp-3025	785	2	101	101	NUM
fnp-3025	785	3	-	-	SYM
fnp-3025	785	4	12	12	NUM
fnp-3025	785	5	.	.	PUNCT
fnp-3025	786	1	32	32	NUM
fnp-3025	786	2	.	.	PUNCT
fnp-3025	787	1	tomiyama	tomiyama	PROPN
fnp-3025	787	2	,	,	PUNCT
fnp-3025	787	3	t.	t.	PROPN
fnp-3025	787	4	and	and	CCONJ
fnp-3025	787	5	h.	h.	PROPN
fnp-3025	787	6	shimada	shimada	PROPN
fnp-3025	787	7	,	,	PUNCT
fnp-3025	787	8	app	app	PROPN
fnp-3025	787	9	osaka	osaka	PROPN
fnp-3025	787	10	mutation	mutation	NOUN
fnp-3025	787	11	in	in	ADP
fnp-3025	787	12	familial	familial	ADJ
fnp-3025	787	13	alzheimer	alzheimer	PROPN
fnp-3025	787	14	’s	’s	PART
fnp-3025	787	15	disease	disease	NOUN
fnp-3025	787	16	-	-	PUNCT
fnp-3025	787	17	its	its	PRON
fnp-3025	787	18	discovery	discovery	NOUN
fnp-3025	787	19	,	,	PUNCT
fnp-3025	787	20	phenotypes	phenotype	NOUN
fnp-3025	787	21	,	,	PUNCT
fnp-3025	787	22	and	and	CCONJ
fnp-3025	787	23	mechanism	mechanism	NOUN
fnp-3025	787	24	of	of	ADP
fnp-3025	787	25	recessive	recessive	ADJ
fnp-3025	787	26	inheritance	inheritance	NOUN
fnp-3025	787	27	.	.	PUNCT
fnp-3025	788	1	int	int	PROPN
fnp-3025	788	2	j	j	PROPN
fnp-3025	788	3	mol	mol	ADP
fnp-3025	788	4	sci	sci	PROPN
fnp-3025	788	5	,	,	PUNCT
fnp-3025	788	6	2020	2020	NUM
fnp-3025	788	7	.	.	PUNCT
fnp-3025	789	1	21(4	21(4	NUM
fnp-3025	789	2	):	):	PUNCT
fnp-3025	789	3	p.	p.	NOUN
fnp-3025	789	4	1413	1413	NUM
fnp-3025	789	5	.	.	PUNCT
fnp-3025	790	1	33	33	NUM
fnp-3025	790	2	.	.	PUNCT
fnp-3025	791	1	walsh	walsh	PROPN
fnp-3025	791	2	,	,	PUNCT
fnp-3025	791	3	d.m	d.m	PROPN
fnp-3025	791	4	.	.	PROPN
fnp-3025	791	5	and	and	CCONJ
fnp-3025	791	6	d.j	d.j	PROPN
fnp-3025	791	7	.	.	PROPN
fnp-3025	791	8	selkoe	selkoe	PROPN
fnp-3025	791	9	,	,	PUNCT
fnp-3025	791	10	amyloid	amyloid	NOUN
fnp-3025	791	11	beta	beta	NOUN
fnp-3025	791	12	-	-	PUNCT
fnp-3025	791	13	protein	protein	NOUN
fnp-3025	791	14	and	and	CCONJ
fnp-3025	791	15	beyond	beyond	ADP
fnp-3025	791	16	:	:	PUNCT
fnp-3025	791	17	the	the	DET
fnp-3025	791	18	path	path	NOUN
fnp-3025	791	19	forward	forward	ADV
fnp-3025	791	20	in	in	ADP
fnp-3025	791	21	alzheimer	alzheimer	PROPN
fnp-3025	791	22	’s	’s	PART
fnp-3025	791	23	disease	disease	NOUN
fnp-3025	791	24	.	.	PUNCT
fnp-3025	792	1	curr	curr	PROPN
fnp-3025	792	2	opin	opin	PROPN
fnp-3025	792	3	neurobiol	neurobiol	PROPN
fnp-3025	792	4	,	,	PUNCT
fnp-3025	792	5	2020	2020	NUM
fnp-3025	792	6	.	.	PUNCT
fnp-3025	793	1	61	61	NUM
fnp-3025	793	2	:	:	PUNCT
fnp-3025	793	3	p.	p.	NOUN
fnp-3025	793	4	116	116	NUM
fnp-3025	793	5	-	-	SYM
fnp-3025	793	6	124	124	NUM
fnp-3025	793	7	.	.	PUNCT
fnp-3025	793	8	34	34	NUM
fnp-3025	793	9	.	.	PUNCT
fnp-3025	793	10	flagmeier	flagmeier	NOUN
fnp-3025	793	11	,	,	PUNCT
fnp-3025	793	12	p.	p.	PROPN
fnp-3025	793	13	,	,	PUNCT
fnp-3025	793	14	et	et	PROPN
fnp-3025	793	15	al	al	PROPN
fnp-3025	793	16	.	.	PROPN
fnp-3025	793	17	,	,	PUNCT
fnp-3025	793	18	direct	direct	ADJ
fnp-3025	793	19	measurement	measurement	NOUN
fnp-3025	793	20	of	of	ADP
fnp-3025	793	21	lipid	lipid	ADJ
fnp-3025	793	22	membrane	membrane	NOUN
fnp-3025	793	23	disruption	disruption	NOUN
fnp-3025	793	24	connects	connect	VERB
fnp-3025	793	25	kinetics	kinetic	NOUN
fnp-3025	793	26	and	and	CCONJ
fnp-3025	793	27	toxicity	toxicity	NOUN
fnp-3025	793	28	of	of	ADP
fnp-3025	793	29	abeta42	abeta42	NOUN
fnp-3025	793	30	aggregation	aggregation	NOUN
fnp-3025	793	31	.	.	PUNCT
fnp-3025	794	1	nat	nat	PROPN
fnp-3025	794	2	struct	struct	NOUN
fnp-3025	794	3	mol	mol	ADP
fnp-3025	794	4	biol	biol	PROPN
fnp-3025	794	5	,	,	PUNCT
fnp-3025	794	6	2020	2020	NUM
fnp-3025	794	7	.	.	PUNCT
fnp-3025	795	1	27(10	27(10	NUM
fnp-3025	795	2	):	):	PUNCT
fnp-3025	795	3	p.	p.	NOUN
fnp-3025	795	4	886	886	NUM
fnp-3025	795	5	-	-	SYM
fnp-3025	795	6	891	891	NUM
fnp-3025	795	7	.	.	PUNCT
fnp-3025	795	8	35	35	NUM
fnp-3025	795	9	.	.	PUNCT
fnp-3025	796	1	chen	chen	PROPN
fnp-3025	796	2	,	,	PUNCT
fnp-3025	796	3	x.q	x.q	PROPN
fnp-3025	796	4	.	.	PROPN
fnp-3025	796	5	and	and	CCONJ
fnp-3025	796	6	w.c	w.c	PROPN
fnp-3025	796	7	.	.	PROPN
fnp-3025	796	8	mobley	mobley	PROPN
fnp-3025	796	9	,	,	PUNCT
fnp-3025	796	10	alzheimer	alzheimer	PROPN
fnp-3025	796	11	disease	disease	NOUN
fnp-3025	796	12	pathogenesis	pathogenesis	NOUN
fnp-3025	796	13	:	:	PUNCT
fnp-3025	796	14	insights	insight	NOUN
fnp-3025	796	15	from	from	ADP
fnp-3025	796	16	molecular	molecular	ADJ
fnp-3025	796	17	and	and	CCONJ
fnp-3025	796	18	cellular	cellular	ADJ
fnp-3025	796	19	biology	biology	NOUN
fnp-3025	796	20	studies	study	NOUN
fnp-3025	796	21	of	of	ADP
fnp-3025	796	22	oligomeric	oligomeric	ADJ
fnp-3025	796	23	abeta	abeta	NOUN
fnp-3025	796	24	and	and	CCONJ
fnp-3025	796	25	tau	tau	PROPN
fnp-3025	796	26	species	specie	NOUN
fnp-3025	796	27	.	.	PUNCT
fnp-3025	797	1	front	front	ADJ
fnp-3025	797	2	neurosci	neurosci	PROPN
fnp-3025	797	3	,	,	PUNCT
fnp-3025	797	4	2019	2019	NUM
fnp-3025	797	5	.	.	PUNCT
fnp-3025	798	1	13	13	NUM
fnp-3025	798	2	:	:	PUNCT
fnp-3025	799	1	p.	p.	NOUN
fnp-3025	799	2	659	659	NUM
fnp-3025	799	3	.	.	PUNCT
fnp-3025	799	4	36	36	NUM
fnp-3025	799	5	.	.	PUNCT
fnp-3025	800	1	esparza	esparza	PROPN
fnp-3025	800	2	,	,	PUNCT
fnp-3025	800	3	t.j	t.j	PROPN
fnp-3025	800	4	.	.	PROPN
fnp-3025	800	5	,	,	PUNCT
fnp-3025	800	6	et	et	PROPN
fnp-3025	800	7	al	al	PROPN
fnp-3025	800	8	.	.	PROPN
fnp-3025	800	9	,	,	PUNCT
fnp-3025	800	10	amyloid	amyloid	NOUN
fnp-3025	800	11	-	-	PUNCT
fnp-3025	800	12	beta	beta	NOUN
fnp-3025	800	13	oligomerization	oligomerization	NOUN
fnp-3025	800	14	in	in	ADP
fnp-3025	800	15	alzheimer	alzheimer	PROPN
fnp-3025	800	16	dementia	dementia	NOUN
fnp-3025	800	17	versus	versus	ADP
fnp-3025	800	18	high	high	ADJ
fnp-3025	800	19	-	-	PUNCT
fnp-3025	800	20	pathology	pathology	NOUN
fnp-3025	800	21	controls	control	NOUN
fnp-3025	800	22	.	.	PUNCT
fnp-3025	801	1	ann	ann	PROPN
fnp-3025	801	2	neurol	neurol	PROPN
fnp-3025	801	3	,	,	PUNCT
fnp-3025	801	4	2013	2013	NUM
fnp-3025	801	5	.	.	PUNCT
fnp-3025	802	1	73(1	73(1	NUM
fnp-3025	802	2	):	):	PUNCT
fnp-3025	803	1	p.	p.	NOUN
fnp-3025	803	2	104	104	NUM
fnp-3025	803	3	-	-	SYM
fnp-3025	803	4	19	19	NUM
fnp-3025	803	5	.	.	PUNCT
fnp-3025	803	6	37	37	NUM
fnp-3025	803	7	.	.	PUNCT
fnp-3025	804	1	shankar	shankar	PROPN
fnp-3025	804	2	,	,	PUNCT
fnp-3025	804	3	g.m	g.m	PROPN
fnp-3025	804	4	.	.	PROPN
fnp-3025	804	5	,	,	PUNCT
fnp-3025	804	6	et	et	PROPN
fnp-3025	804	7	al	al	PROPN
fnp-3025	804	8	.	.	PROPN
fnp-3025	804	9	,	,	PUNCT
fnp-3025	804	10	amyloid	amyloid	NOUN
fnp-3025	804	11	-	-	PUNCT
fnp-3025	804	12	beta	beta	NOUN
fnp-3025	804	13	protein	protein	NOUN
fnp-3025	804	14	dimers	dimer	NOUN
fnp-3025	804	15	isolated	isolate	VERB
fnp-3025	804	16	directly	directly	ADV
fnp-3025	804	17	from	from	ADP
fnp-3025	804	18	alzheimer	alzheimer	PROPN
fnp-3025	804	19	’s	’s	PART
fnp-3025	804	20	brains	brain	NOUN
fnp-3025	804	21	impair	impair	VERB
fnp-3025	804	22	synaptic	synaptic	ADJ
fnp-3025	804	23	plasticity	plasticity	NOUN
fnp-3025	804	24	and	and	CCONJ
fnp-3025	804	25	memory	memory	NOUN
fnp-3025	804	26	.	.	PUNCT
fnp-3025	805	1	nat	nat	PROPN
fnp-3025	805	2	med	med	PROPN
fnp-3025	805	3	,	,	PUNCT
fnp-3025	805	4	2008	2008	NUM
fnp-3025	805	5	.	.	PUNCT
fnp-3025	806	1	14(8	14(8	X
fnp-3025	806	2	):	):	PUNCT
fnp-3025	807	1	p.	p.	NOUN
fnp-3025	807	2	837	837	NUM
fnp-3025	807	3	-	-	SYM
fnp-3025	807	4	42	42	NUM
fnp-3025	807	5	.	.	PUNCT
fnp-3025	807	6	38	38	NUM
fnp-3025	807	7	.	.	PUNCT
fnp-3025	808	1	hyman	hyman	PROPN
fnp-3025	808	2	,	,	PUNCT
fnp-3025	808	3	b.t	b.t	PROPN
fnp-3025	808	4	.	.	PROPN
fnp-3025	808	5	,	,	PUNCT
fnp-3025	808	6	anatomical	anatomical	ADJ
fnp-3025	808	7	changes	change	NOUN
fnp-3025	808	8	underlying	underlie	VERB
fnp-3025	808	9	dementia	dementia	NOUN
fnp-3025	808	10	in	in	ADP
fnp-3025	808	11	alzheimer	alzheimer	PROPN
fnp-3025	808	12	’s	’s	PART
fnp-3025	808	13	disease	disease	NOUN
fnp-3025	808	14	,	,	PUNCT
fnp-3025	808	15	in	in	ADP
fnp-3025	808	16	alzheimer	alzheimer	PROPN
fnp-3025	808	17	:	:	PUNCT
fnp-3025	808	18	100	100	NUM
fnp-3025	808	19	years	year	NOUN
fnp-3025	808	20	and	and	CCONJ
fnp-3025	808	21	beyond	beyond	ADP
fnp-3025	808	22	,	,	PUNCT
fnp-3025	808	23	m.	m.	NOUN
fnp-3025	808	24	jucker	jucker	NOUN
fnp-3025	808	25	,	,	PUNCT
fnp-3025	808	26	et	et	PROPN
fnp-3025	808	27	al	al	PROPN
fnp-3025	808	28	.	.	PROPN
fnp-3025	808	29	,	,	PUNCT
fnp-3025	808	30	editors	editor	NOUN
fnp-3025	808	31	.	.	PUNCT
fnp-3025	809	1	2006	2006	NUM
fnp-3025	809	2	,	,	PUNCT
fnp-3025	809	3	springer	springer	NOUN
fnp-3025	809	4	-	-	PUNCT
fnp-3025	809	5	verlag	verlag	PROPN
fnp-3025	809	6	:	:	PUNCT
fnp-3025	809	7	berlin	berlin	PROPN
fnp-3025	809	8	heidelberg	heidelberg	PROPN
fnp-3025	809	9	new	new	PROPN
fnp-3025	809	10	york	york	PROPN
fnp-3025	809	11	.	.	PUNCT
fnp-3025	810	1	p.	p.	NOUN
fnp-3025	810	2	89	89	NUM
fnp-3025	810	3	-	-	SYM
fnp-3025	810	4	94	94	NUM
fnp-3025	810	5	.	.	PUNCT
fnp-3025	810	6	39	39	NUM
fnp-3025	810	7	.	.	PUNCT
fnp-3025	811	1	koffie	koffie	PROPN
fnp-3025	811	2	,	,	PUNCT
fnp-3025	811	3	r.m	r.m	PROPN
fnp-3025	811	4	.	.	PROPN
fnp-3025	811	5	,	,	PUNCT
fnp-3025	811	6	et	et	PROPN
fnp-3025	811	7	al	al	PROPN
fnp-3025	811	8	.	.	PROPN
fnp-3025	811	9	,	,	PUNCT
fnp-3025	811	10	oligomeric	oligomeric	ADJ
fnp-3025	811	11	amyloid	amyloid	NOUN
fnp-3025	811	12	beta	beta	ADJ
fnp-3025	811	13	associates	associate	NOUN
fnp-3025	811	14	with	with	ADP
fnp-3025	811	15	postsynaptic	postsynaptic	ADJ
fnp-3025	811	16	densities	density	NOUN
fnp-3025	811	17	and	and	CCONJ
fnp-3025	811	18	correlates	correlate	VERB
fnp-3025	811	19	with	with	ADP
fnp-3025	811	20	excitatory	excitatory	ADJ
fnp-3025	811	21	synapse	synapse	NOUN
fnp-3025	811	22	loss	loss	NOUN
fnp-3025	811	23	near	near	ADP
fnp-3025	811	24	senile	senile	ADJ
fnp-3025	811	25	plaques	plaque	NOUN
fnp-3025	811	26	.	.	PUNCT
fnp-3025	812	1	proc	proc	PROPN
fnp-3025	812	2	natl	natl	PROPN
fnp-3025	812	3	acad	acad	PROPN
fnp-3025	812	4	sci	sci	PROPN
fnp-3025	812	5	u	u	PROPN
fnp-3025	812	6	s	s	PROPN
fnp-3025	812	7	a	a	PRON
fnp-3025	812	8	,	,	PUNCT
fnp-3025	812	9	2009	2009	NUM
fnp-3025	812	10	.	.	PUNCT
fnp-3025	813	1	106(10	106(10	NUM
fnp-3025	813	2	):	):	PUNCT
fnp-3025	813	3	p.	p.	NOUN
fnp-3025	813	4	4012	4012	NUM
fnp-3025	813	5	-	-	SYM
fnp-3025	813	6	7	7	NUM
fnp-3025	813	7	.	.	NUM
fnp-3025	813	8	40	40	NUM
fnp-3025	813	9	.	.	PUNCT
fnp-3025	814	1	katzmarski	katzmarski	PROPN
fnp-3025	814	2	,	,	PUNCT
fnp-3025	814	3	n.	n.	PROPN
fnp-3025	814	4	,	,	PUNCT
fnp-3025	814	5	et	et	PROPN
fnp-3025	814	6	al	al	PROPN
fnp-3025	814	7	.	.	PROPN
fnp-3025	814	8	,	,	PUNCT
fnp-3025	814	9	abeta	abeta	PROPN
fnp-3025	814	10	oligomers	oligomer	NOUN
fnp-3025	814	11	trigger	trigger	NOUN
fnp-3025	814	12	and	and	CCONJ
fnp-3025	814	13	accelerate	accelerate	VERB
fnp-3025	814	14	abeta	abeta	NOUN
fnp-3025	814	15	seeding	seeding	NOUN
fnp-3025	814	16	.	.	PUNCT
fnp-3025	815	1	brain	brain	NOUN
fnp-3025	815	2	pathol	pathol	NOUN
fnp-3025	815	3	,	,	PUNCT
fnp-3025	815	4	2020	2020	NUM
fnp-3025	815	5	.	.	PUNCT
fnp-3025	816	1	30(1	30(1	NUM
fnp-3025	816	2	):	):	PUNCT
fnp-3025	817	1	p.	p.	NOUN
fnp-3025	817	2	36	36	NUM
fnp-3025	817	3	-	-	SYM
fnp-3025	817	4	45	45	NUM
fnp-3025	817	5	.	.	NOUN
fnp-3025	817	6	41	41	NUM
fnp-3025	817	7	.	.	PUNCT
fnp-3025	818	1	langer	langer	PROPN
fnp-3025	818	2	,	,	PUNCT
fnp-3025	818	3	f.	f.	PROPN
fnp-3025	818	4	,	,	PUNCT
fnp-3025	818	5	et	et	PROPN
fnp-3025	818	6	al	al	PROPN
fnp-3025	818	7	.	.	PROPN
fnp-3025	818	8	,	,	PUNCT
fnp-3025	818	9	soluble	soluble	ADJ
fnp-3025	818	10	abeta	abeta	NOUN
fnp-3025	818	11	seeds	seed	NOUN
fnp-3025	818	12	are	be	AUX
fnp-3025	818	13	potent	potent	ADJ
fnp-3025	818	14	inducers	inducer	NOUN
fnp-3025	818	15	of	of	ADP
fnp-3025	818	16	cerebral	cerebral	ADJ
fnp-3025	818	17	beta	beta	NOUN
fnp-3025	818	18	-	-	PUNCT
fnp-3025	818	19	amyloid	amyloid	NOUN
fnp-3025	818	20	deposition	deposition	NOUN
fnp-3025	818	21	.	.	PUNCT
fnp-3025	819	1	j	j	PROPN
fnp-3025	819	2	neurosci	neurosci	PROPN
fnp-3025	819	3	,	,	PUNCT
fnp-3025	819	4	2011	2011	NUM
fnp-3025	819	5	.	.	PUNCT
fnp-3025	820	1	31(41	31(41	NUM
fnp-3025	820	2	):	):	PUNCT
fnp-3025	820	3	p.	p.	NOUN
fnp-3025	820	4	14488	14488	NUM
fnp-3025	820	5	-	-	SYM
fnp-3025	820	6	95	95	NUM
fnp-3025	820	7	.	.	PUNCT
fnp-3025	821	1	42	42	NUM
fnp-3025	821	2	.	.	PUNCT
fnp-3025	822	1	benilova	benilova	PROPN
fnp-3025	822	2	,	,	PUNCT
fnp-3025	822	3	i.	i.	PROPN
fnp-3025	822	4	,	,	PUNCT
fnp-3025	822	5	et	et	PROPN
fnp-3025	822	6	al	al	PROPN
fnp-3025	822	7	.	.	PROPN
fnp-3025	822	8	,	,	PUNCT
fnp-3025	822	9	highly	highly	ADV
fnp-3025	822	10	infectious	infectious	ADJ
fnp-3025	822	11	prions	prion	NOUN
fnp-3025	822	12	are	be	AUX
fnp-3025	822	13	not	not	PART
fnp-3025	822	14	directly	directly	ADV
fnp-3025	822	15	neurotoxic	neurotoxic	ADJ
fnp-3025	822	16	.	.	PUNCT
fnp-3025	823	1	proc	proc	PROPN
fnp-3025	823	2	natl	natl	PROPN
fnp-3025	823	3	acad	acad	PROPN
fnp-3025	823	4	sci	sci	PROPN
fnp-3025	823	5	u	u	PROPN
fnp-3025	823	6	s	s	PROPN
fnp-3025	823	7	a	a	PRON
fnp-3025	823	8	,	,	PUNCT
fnp-3025	823	9	2020	2020	NUM
fnp-3025	823	10	.	.	PUNCT
fnp-3025	824	1	117(38	117(38	NUM
fnp-3025	824	2	):	):	PUNCT
fnp-3025	824	3	p.	p.	NOUN
fnp-3025	824	4	23815	23815	NUM
fnp-3025	824	5	-	-	SYM
fnp-3025	824	6	23822	23822	NUM
fnp-3025	824	7	.	.	PUNCT
fnp-3025	825	1	43	43	NUM
fnp-3025	825	2	.	.	PUNCT
fnp-3025	826	1	benilova	benilova	PROPN
fnp-3025	826	2	,	,	PUNCT
fnp-3025	826	3	i.	i.	PROPN
fnp-3025	826	4	,	,	PUNCT
fnp-3025	826	5	e.	e.	PROPN
fnp-3025	826	6	karran	karran	PROPN
fnp-3025	826	7	,	,	PUNCT
fnp-3025	826	8	and	and	CCONJ
fnp-3025	826	9	b.	b.	PROPN
fnp-3025	826	10	de	de	PROPN
fnp-3025	826	11	strooper	strooper	PROPN
fnp-3025	826	12	,	,	PUNCT
fnp-3025	826	13	the	the	DET
fnp-3025	826	14	toxic	toxic	ADJ
fnp-3025	826	15	abeta	abeta	NOUN
fnp-3025	826	16	oligomer	oligomer	PROPN
fnp-3025	826	17	and	and	CCONJ
fnp-3025	826	18	alzheimer	alzheimer	PROPN
fnp-3025	826	19	’s	’s	PART
fnp-3025	826	20	disease	disease	NOUN
fnp-3025	826	21	:	:	PUNCT
fnp-3025	826	22	an	an	DET
fnp-3025	826	23	emperor	emperor	NOUN
fnp-3025	826	24	in	in	ADP
fnp-3025	826	25	need	need	NOUN
fnp-3025	826	26	of	of	ADP
fnp-3025	826	27	clothes	clothe	NOUN
fnp-3025	826	28	.	.	PUNCT
fnp-3025	827	1	nat	nat	PROPN
fnp-3025	827	2	neurosci	neurosci	PROPN
fnp-3025	827	3	,	,	PUNCT
fnp-3025	827	4	2012	2012	NUM
fnp-3025	827	5	.	.	PUNCT
fnp-3025	827	6	15(3	15(3	NUM
fnp-3025	827	7	):	):	PUNCT
fnp-3025	827	8	p.	p.	NOUN
fnp-3025	827	9	349	349	NUM
fnp-3025	827	10	-	-	SYM
fnp-3025	827	11	57	57	NUM
fnp-3025	827	12	.	.	PUNCT
fnp-3025	827	13	44	44	NUM
fnp-3025	827	14	.	.	PUNCT
fnp-3025	828	1	hardy	hardy	ADJ
fnp-3025	828	2	,	,	PUNCT
fnp-3025	828	3	j.	j.	PROPN
fnp-3025	828	4	and	and	CCONJ
fnp-3025	828	5	d.j	d.j	PROPN
fnp-3025	828	6	.	.	PROPN
fnp-3025	828	7	selkoe	selkoe	PROPN
fnp-3025	828	8	,	,	PUNCT
fnp-3025	828	9	the	the	DET
fnp-3025	828	10	amyloid	amyloid	NOUN
fnp-3025	828	11	hypothesis	hypothesis	NOUN
fnp-3025	828	12	of	of	ADP
fnp-3025	828	13	alzheimer	alzheimer	PROPN
fnp-3025	828	14	’s	’s	PART
fnp-3025	828	15	disease	disease	NOUN
fnp-3025	828	16	:	:	PUNCT
fnp-3025	828	17	progress	progress	NOUN
fnp-3025	828	18	and	and	CCONJ
fnp-3025	828	19	problems	problem	NOUN
fnp-3025	828	20	on	on	ADP
fnp-3025	828	21	the	the	DET
fnp-3025	828	22	road	road	NOUN
fnp-3025	828	23	to	to	ADP
fnp-3025	828	24	therapeutics	therapeutic	NOUN
fnp-3025	828	25	.	.	PUNCT
fnp-3025	829	1	science	science	NOUN
fnp-3025	829	2	,	,	PUNCT
fnp-3025	829	3	2002	2002	NUM
fnp-3025	829	4	.	.	PUNCT
fnp-3025	830	1	297(5580	297(5580	NUM
fnp-3025	830	2	):	):	PUNCT
fnp-3025	831	1	p.	p.	NOUN
fnp-3025	831	2	353	353	NUM
fnp-3025	831	3	-	-	SYM
fnp-3025	831	4	6	6	NUM
fnp-3025	831	5	.	.	X
fnp-3025	831	6	45	45	NUM
fnp-3025	831	7	.	.	X
fnp-3025	831	8	walker	walker	PROPN
fnp-3025	831	9	,	,	PUNCT
fnp-3025	831	10	l.c	l.c	PROPN
fnp-3025	831	11	.	.	PROPN
fnp-3025	831	12	,	,	PUNCT
fnp-3025	831	13	d.g	d.g	PROPN
fnp-3025	831	14	.	.	PROPN
fnp-3025	831	15	lynn	lynn	PROPN
fnp-3025	831	16	,	,	PUNCT
fnp-3025	831	17	and	and	CCONJ
fnp-3025	831	18	y.o	y.o	PROPN
fnp-3025	831	19	.	.	PROPN
fnp-3025	831	20	chernoff	chernoff	PROPN
fnp-3025	831	21	,	,	PUNCT
fnp-3025	831	22	a	a	DET
fnp-3025	831	23	standard	standard	ADJ
fnp-3025	831	24	model	model	NOUN
fnp-3025	831	25	of	of	ADP
fnp-3025	831	26	alzheimer	alzheimer	PROPN
fnp-3025	831	27	’s	’s	PART
fnp-3025	831	28	disease	disease	NOUN
fnp-3025	831	29	?	?	PUNCT
fnp-3025	832	1	prion	prion	NOUN
fnp-3025	832	2	,	,	PUNCT
fnp-3025	832	3	2018	2018	NUM
fnp-3025	832	4	.	.	PUNCT
fnp-3025	833	1	12(5	12(5	NUM
fnp-3025	833	2	-	-	SYM
fnp-3025	833	3	6	6	NUM
fnp-3025	833	4	):	):	PUNCT
fnp-3025	833	5	p.	p.	NOUN
fnp-3025	833	6	261	261	NUM
fnp-3025	833	7	-	-	SYM
fnp-3025	833	8	265	265	NUM
fnp-3025	833	9	.	.	PUNCT
fnp-3025	834	1	46	46	NUM
fnp-3025	834	2	.	.	PUNCT
fnp-3025	835	1	wiseman	wiseman	PROPN
fnp-3025	835	2	,	,	PUNCT
fnp-3025	835	3	f.k	f.k	PROPN
fnp-3025	835	4	.	.	PROPN
fnp-3025	835	5	,	,	PUNCT
fnp-3025	835	6	et	et	PROPN
fnp-3025	835	7	al	al	PROPN
fnp-3025	835	8	.	.	PROPN
fnp-3025	835	9	,	,	PUNCT
fnp-3025	835	10	a	a	DET
fnp-3025	835	11	genetic	genetic	ADJ
fnp-3025	835	12	cause	cause	NOUN
fnp-3025	835	13	of	of	ADP
fnp-3025	835	14	alzheimer	alzheimer	PROPN
fnp-3025	835	15	disease	disease	PROPN
fnp-3025	835	16	:	:	PUNCT
fnp-3025	835	17	mechanistic	mechanistic	ADJ
fnp-3025	835	18	insights	insight	NOUN
fnp-3025	835	19	from	from	ADP
fnp-3025	835	20	down	down	ADP
fnp-3025	835	21	syndrome	syndrome	NOUN
fnp-3025	835	22	.	.	PUNCT
fnp-3025	836	1	nat	nat	PROPN
fnp-3025	836	2	rev	rev	PROPN
fnp-3025	836	3	neurosci	neurosci	PROPN
fnp-3025	836	4	,	,	PUNCT
fnp-3025	836	5	2015	2015	NUM
fnp-3025	836	6	.	.	PUNCT
fnp-3025	837	1	16(9	16(9	NUM
fnp-3025	837	2	):	):	PUNCT
fnp-3025	838	1	p.	p.	NOUN
fnp-3025	838	2	564	564	NUM
fnp-3025	838	3	-	-	SYM
fnp-3025	838	4	74	74	NUM
fnp-3025	838	5	.	.	PUNCT
fnp-3025	839	1	47	47	NUM
fnp-3025	839	2	.	.	PUNCT
fnp-3025	840	1	abrahamson	abrahamson	PROPN
fnp-3025	840	2	,	,	PUNCT
fnp-3025	840	3	e.e	e.e	PROPN
fnp-3025	840	4	.	.	PROPN
fnp-3025	840	5	,	,	PUNCT
fnp-3025	840	6	et	et	PROPN
fnp-3025	840	7	al	al	PROPN
fnp-3025	840	8	.	.	PROPN
fnp-3025	840	9	,	,	PUNCT
fnp-3025	840	10	neuropathological	neuropathological	PROPN
fnp-3025	840	11	correlates	correlate	VERB
fnp-3025	840	12	of	of	ADP
fnp-3025	840	13	amyloid	amyloid	NOUN
fnp-3025	840	14	pet	pet	ADJ
fnp-3025	840	15	imaging	imaging	NOUN
fnp-3025	840	16	in	in	ADP
fnp-3025	840	17	down	down	ADP
fnp-3025	840	18	syndrome	syndrome	NOUN
fnp-3025	840	19	.	.	PUNCT
fnp-3025	841	1	dev	dev	PROPN
fnp-3025	841	2	neurobiol	neurobiol	PROPN
fnp-3025	841	3	,	,	PUNCT
fnp-3025	841	4	2019	2019	NUM
fnp-3025	841	5	.	.	PUNCT
fnp-3025	842	1	79(7	79(7	NUM
fnp-3025	842	2	):	):	PUNCT
fnp-3025	842	3	p.	p.	NOUN
fnp-3025	842	4	750	750	NUM
fnp-3025	842	5	-	-	SYM
fnp-3025	842	6	766	766	NUM
fnp-3025	842	7	.	.	PUNCT
fnp-3025	843	1	48	48	NUM
fnp-3025	843	2	.	.	PUNCT
fnp-3025	844	1	jonsson	jonsson	PROPN
fnp-3025	844	2	,	,	PUNCT
fnp-3025	844	3	t.	t.	PROPN
fnp-3025	844	4	,	,	PUNCT
fnp-3025	844	5	et	et	PROPN
fnp-3025	844	6	al	al	PROPN
fnp-3025	844	7	.	.	PROPN
fnp-3025	844	8	,	,	PUNCT
fnp-3025	844	9	a	a	DET
fnp-3025	844	10	mutation	mutation	NOUN
fnp-3025	844	11	in	in	ADP
fnp-3025	844	12	app	app	PROPN
fnp-3025	844	13	protects	protect	NOUN
fnp-3025	844	14	against	against	ADP
fnp-3025	844	15	alzheimer	alzheimer	PROPN
fnp-3025	844	16	’s	’s	PART
fnp-3025	844	17	disease	disease	NOUN
fnp-3025	844	18	and	and	CCONJ
fnp-3025	844	19	age	age	NOUN
fnp-3025	844	20	-	-	PUNCT
fnp-3025	844	21	related	relate	VERB
fnp-3025	844	22	cognitive	cognitive	ADJ
fnp-3025	844	23	decline	decline	NOUN
fnp-3025	844	24	.	.	PUNCT
fnp-3025	845	1	nature	nature	NOUN
fnp-3025	845	2	,	,	PUNCT
fnp-3025	845	3	2012	2012	NUM
fnp-3025	845	4	.	.	PUNCT
fnp-3025	846	1	488(7409	488(7409	NUM
fnp-3025	846	2	):	):	PUNCT
fnp-3025	846	3	p.	p.	NOUN
fnp-3025	846	4	96	96	NUM
fnp-3025	846	5	-	-	SYM
fnp-3025	846	6	9	9	NUM
fnp-3025	846	7	.	.	NUM
fnp-3025	846	8	49	49	NUM
fnp-3025	846	9	.	.	PUNCT
fnp-3025	847	1	benilova	benilova	PROPN
fnp-3025	847	2	,	,	PUNCT
fnp-3025	847	3	i.	i.	PROPN
fnp-3025	847	4	,	,	PUNCT
fnp-3025	847	5	et	et	PROPN
fnp-3025	847	6	al	al	PROPN
fnp-3025	847	7	.	.	PROPN
fnp-3025	847	8	,	,	PUNCT
fnp-3025	847	9	the	the	DET
fnp-3025	847	10	alzheimer	alzheimer	PROPN
fnp-3025	847	11	disease	disease	PROPN
fnp-3025	847	12	protective	protective	ADJ
fnp-3025	847	13	mutation	mutation	NOUN
fnp-3025	847	14	a2	a2	PROPN
fnp-3025	847	15	t	t	NOUN
fnp-3025	847	16	modulates	modulate	NOUN
fnp-3025	847	17	kinetic	kinetic	ADJ
fnp-3025	847	18	and	and	CCONJ
fnp-3025	847	19	thermodynamic	thermodynamic	ADJ
fnp-3025	847	20	properties	property	NOUN
fnp-3025	847	21	of	of	ADP
fnp-3025	847	22	amyloid	amyloid	NOUN
fnp-3025	847	23	-	-	PUNCT
fnp-3025	847	24	beta	beta	NOUN
fnp-3025	847	25	(	(	PUNCT
fnp-3025	847	26	abeta	abeta	ADJ
fnp-3025	847	27	)	)	PUNCT
fnp-3025	847	28	aggregation	aggregation	NOUN
fnp-3025	847	29	.	.	PUNCT
fnp-3025	848	1	j	j	PROPN
fnp-3025	848	2	biol	biol	PROPN
fnp-3025	848	3	chem	chem	PROPN
fnp-3025	848	4	,	,	PUNCT
fnp-3025	848	5	2014	2014	NUM
fnp-3025	848	6	.	.	PUNCT
fnp-3025	849	1	289(45	289(45	NUM
fnp-3025	849	2	):	):	PUNCT
fnp-3025	849	3	p.	p.	NOUN
fnp-3025	849	4	30977	30977	NUM
fnp-3025	849	5	-	-	SYM
fnp-3025	849	6	89	89	NUM
fnp-3025	849	7	.	.	PUNCT
fnp-3025	850	1	50	50	NUM
fnp-3025	850	2	.	.	X
fnp-3025	851	1	kero	kero	PROPN
fnp-3025	851	2	,	,	PUNCT
fnp-3025	851	3	m.	m.	NOUN
fnp-3025	851	4	,	,	PUNCT
fnp-3025	851	5	et	et	PROPN
fnp-3025	851	6	al	al	PROPN
fnp-3025	851	7	.	.	PROPN
fnp-3025	851	8	,	,	PUNCT
fnp-3025	851	9	amyloid	amyloid	NOUN
fnp-3025	851	10	precursor	precursor	NOUN
fnp-3025	851	11	protein	protein	NOUN
fnp-3025	851	12	(	(	PUNCT
fnp-3025	851	13	app	app	NOUN
fnp-3025	851	14	)	)	PUNCT
fnp-3025	851	15	a673	a673	PROPN
fnp-3025	851	16	t	t	NOUN
fnp-3025	851	17	mutation	mutation	NOUN
fnp-3025	851	18	in	in	ADP
fnp-3025	851	19	the	the	DET
fnp-3025	851	20	elderly	elderly	ADJ
fnp-3025	851	21	finnish	finnish	ADJ
fnp-3025	851	22	population	population	NOUN
fnp-3025	851	23	.	.	PUNCT
fnp-3025	852	1	neurobiol	neurobiol	PROPN
fnp-3025	852	2	aging	aging	NOUN
fnp-3025	852	3	,	,	PUNCT
fnp-3025	852	4	2013	2013	NUM
fnp-3025	852	5	.	.	PUNCT
fnp-3025	853	1	34(5	34(5	NUM
fnp-3025	853	2	):	):	PUNCT
fnp-3025	854	1	p.	p.	NOUN
fnp-3025	854	2	1518	1518	NUM
fnp-3025	854	3	e1	e1	NOUN
fnp-3025	854	4	-	-	PUNCT
fnp-3025	854	5	3	3	NUM
fnp-3025	854	6	.	.	NOUN
fnp-3025	854	7	51	51	NUM
fnp-3025	854	8	.	.	PUNCT
fnp-3025	854	9	di	di	PROPN
fnp-3025	854	10	fede	fede	PROPN
fnp-3025	854	11	,	,	PUNCT
fnp-3025	854	12	g.	g.	PROPN
fnp-3025	854	13	,	,	PUNCT
fnp-3025	854	14	et	et	PROPN
fnp-3025	854	15	al	al	PROPN
fnp-3025	854	16	.	.	PROPN
fnp-3025	854	17	,	,	PUNCT
fnp-3025	854	18	a	a	DET
fnp-3025	854	19	recessive	recessive	ADJ
fnp-3025	854	20	mutation	mutation	NOUN
fnp-3025	854	21	in	in	ADP
fnp-3025	854	22	the	the	DET
fnp-3025	854	23	app	app	NOUN
fnp-3025	854	24	gene	gene	NOUN
fnp-3025	854	25	with	with	ADP
fnp-3025	854	26	dominant	dominant	ADJ
fnp-3025	854	27	-	-	PUNCT
fnp-3025	854	28	negative	negative	ADJ
fnp-3025	854	29	effect	effect	NOUN
fnp-3025	854	30	on	on	ADP
fnp-3025	854	31	amyloidogenesis	amyloidogenesis	NOUN
fnp-3025	854	32	.	.	PUNCT
fnp-3025	855	1	science	science	NOUN
fnp-3025	855	2	,	,	PUNCT
fnp-3025	855	3	2009	2009	NUM
fnp-3025	855	4	.	.	PUNCT
fnp-3025	856	1	323(5920	323(5920	NUM
fnp-3025	856	2	):	):	PUNCT
fnp-3025	856	3	p.	p.	NOUN
fnp-3025	856	4	1473	1473	NUM
fnp-3025	856	5	-	-	SYM
fnp-3025	856	6	7	7	NUM
fnp-3025	856	7	.	.	NOUN
fnp-3025	856	8	52	52	NUM
fnp-3025	856	9	.	.	PUNCT
fnp-3025	857	1	buxbaum	buxbaum	PROPN
fnp-3025	857	2	,	,	PUNCT
fnp-3025	857	3	j.n	j.n	PROPN
fnp-3025	857	4	.	.	PROPN
fnp-3025	857	5	and	and	CCONJ
fnp-3025	857	6	r.p	r.p	PROPN
fnp-3025	857	7	.	.	PROPN
fnp-3025	857	8	linke	linke	PROPN
fnp-3025	857	9	,	,	PUNCT
fnp-3025	857	10	a	a	DET
fnp-3025	857	11	molecular	molecular	ADJ
fnp-3025	857	12	history	history	NOUN
fnp-3025	857	13	of	of	ADP
fnp-3025	857	14	the	the	DET
fnp-3025	857	15	amyloidoses	amyloidose	NOUN
fnp-3025	857	16	.	.	PUNCT
fnp-3025	858	1	j	j	PROPN
fnp-3025	858	2	mol	mol	ADP
fnp-3025	858	3	biol	biol	PROPN
fnp-3025	858	4	,	,	PUNCT
fnp-3025	858	5	2012	2012	NUM
fnp-3025	858	6	.	.	PUNCT
fnp-3025	859	1	421(2	421(2	NUM
fnp-3025	859	2	-	-	SYM
fnp-3025	859	3	3	3	NUM
fnp-3025	859	4	):	):	PUNCT
fnp-3025	859	5	p.	p.	NOUN
fnp-3025	859	6	142	142	NUM
fnp-3025	859	7	-	-	SYM
fnp-3025	859	8	59	59	NUM
fnp-3025	859	9	.	.	PUNCT
fnp-3025	860	1	53	53	NUM
fnp-3025	860	2	.	.	PUNCT
fnp-3025	860	3	puchtler	puchtler	NOUN
fnp-3025	860	4	,	,	PUNCT
fnp-3025	860	5	h.	h.	PROPN
fnp-3025	860	6	and	and	CCONJ
fnp-3025	860	7	f.	f.	PROPN
fnp-3025	860	8	sweat	sweat	PROPN
fnp-3025	860	9	,	,	PUNCT
fnp-3025	860	10	a	a	DET
fnp-3025	860	11	review	review	NOUN
fnp-3025	860	12	of	of	ADP
fnp-3025	860	13	early	early	ADJ
fnp-3025	860	14	concepts	concept	NOUN
fnp-3025	860	15	of	of	ADP
fnp-3025	860	16	amyloid	amyloid	NOUN
fnp-3025	860	17	in	in	ADP
fnp-3025	860	18	context	context	NOUN
fnp-3025	860	19	with	with	ADP
fnp-3025	860	20	contemporary	contemporary	ADJ
fnp-3025	860	21	chemical	chemical	PROPN
fnp-3025	860	22	literature	literature	NOUN
fnp-3025	860	23	from	from	ADP
fnp-3025	860	24	1839	1839	NUM
fnp-3025	860	25	to	to	ADP
fnp-3025	860	26	1859	1859	NUM
fnp-3025	860	27	.	.	PUNCT
fnp-3025	861	1	j	j	PROPN
fnp-3025	861	2	histochem	histochem	PROPN
fnp-3025	861	3	cytochem	cytochem	PROPN
fnp-3025	861	4	,	,	PUNCT
fnp-3025	861	5	1966	1966	NUM
fnp-3025	861	6	.	.	PUNCT
fnp-3025	862	1	14(2	14(2	NUM
fnp-3025	862	2	):	):	PUNCT
fnp-3025	862	3	p.	p.	NOUN
fnp-3025	862	4	123	123	NUM
fnp-3025	862	5	-	-	SYM
fnp-3025	862	6	34	34	NUM
fnp-3025	862	7	.	.	PUNCT
fnp-3025	862	8	54	54	NUM
fnp-3025	862	9	.	.	PUNCT
fnp-3025	863	1	sipe	sipe	PROPN
fnp-3025	863	2	,	,	PUNCT
fnp-3025	863	3	j.d	j.d	PROPN
fnp-3025	863	4	.	.	PROPN
fnp-3025	863	5	and	and	CCONJ
fnp-3025	863	6	a.s	a.s	PROPN
fnp-3025	863	7	.	.	PROPN
fnp-3025	863	8	cohen	cohen	PROPN
fnp-3025	863	9	,	,	PUNCT
fnp-3025	863	10	review	review	NOUN
fnp-3025	863	11	:	:	PUNCT
fnp-3025	863	12	history	history	NOUN
fnp-3025	863	13	of	of	ADP
fnp-3025	863	14	the	the	DET
fnp-3025	863	15	amyloid	amyloid	NOUN
fnp-3025	863	16	fibril	fibril	NOUN
fnp-3025	863	17	.	.	PUNCT
fnp-3025	864	1	j	j	PROPN
fnp-3025	864	2	struct	struct	NOUN
fnp-3025	864	3	biol	biol	PROPN
fnp-3025	864	4	,	,	PUNCT
fnp-3025	864	5	2000	2000	NUM
fnp-3025	864	6	.	.	PUNCT
fnp-3025	865	1	130(2	130(2	NUM
fnp-3025	865	2	-	-	SYM
fnp-3025	865	3	3	3	NUM
fnp-3025	865	4	):	):	PUNCT
fnp-3025	865	5	p.	p.	NOUN
fnp-3025	865	6	88	88	NUM
fnp-3025	865	7	-	-	SYM
fnp-3025	865	8	98	98	NUM
fnp-3025	865	9	.	.	PUNCT
fnp-3025	866	1	55	55	NUM
fnp-3025	866	2	.	.	X
fnp-3025	867	1	yakupova	yakupova	PROPN
fnp-3025	867	2	,	,	PUNCT
fnp-3025	867	3	e.i	e.i	PROPN
fnp-3025	867	4	.	.	PROPN
fnp-3025	867	5	,	,	PUNCT
fnp-3025	867	6	et	et	PROPN
fnp-3025	867	7	al	al	PROPN
fnp-3025	867	8	.	.	PROPN
fnp-3025	867	9	,	,	PUNCT
fnp-3025	867	10	congo	congo	PROPN
fnp-3025	867	11	red	red	NOUN
fnp-3025	867	12	and	and	CCONJ
fnp-3025	867	13	amyloids	amyloids	PROPN
fnp-3025	867	14	:	:	PUNCT
fnp-3025	867	15	history	history	NOUN
fnp-3025	867	16	and	and	CCONJ
fnp-3025	867	17	relationship	relationship	NOUN
fnp-3025	867	18	.	.	PUNCT
fnp-3025	868	1	biosci	biosci	PROPN
fnp-3025	868	2	rep	rep	PROPN
fnp-3025	868	3	,	,	PUNCT
fnp-3025	868	4	2019	2019	NUM
fnp-3025	868	5	.	.	PUNCT
fnp-3025	869	1	39(1	39(1	NUM
fnp-3025	869	2	):	):	PUNCT
fnp-3025	870	1	p.	p.	NOUN
fnp-3025	870	2	bsr20181415	bsr20181415	NOUN
fnp-3025	870	3	.	.	PUNCT
fnp-3025	871	1	56	56	NUM
fnp-3025	871	2	.	.	PUNCT
fnp-3025	872	1	chiti	chiti	PROPN
fnp-3025	872	2	,	,	PUNCT
fnp-3025	872	3	f.	f.	PROPN
fnp-3025	872	4	and	and	CCONJ
fnp-3025	872	5	c.m	c.m	PROPN
fnp-3025	872	6	.	.	PROPN
fnp-3025	872	7	dobson	dobson	PROPN
fnp-3025	872	8	,	,	PUNCT
fnp-3025	872	9	protein	protein	NOUN
fnp-3025	872	10	misfolding	misfolding	NOUN
fnp-3025	872	11	,	,	PUNCT
fnp-3025	872	12	functional	functional	ADJ
fnp-3025	872	13	amyloid	amyloid	NOUN
fnp-3025	872	14	,	,	PUNCT
fnp-3025	872	15	and	and	CCONJ
fnp-3025	872	16	human	human	ADJ
fnp-3025	872	17	disease	disease	NOUN
fnp-3025	872	18	.	.	PUNCT
fnp-3025	873	1	annu	annu	PROPN
fnp-3025	873	2	rev	rev	VERB
fnp-3025	873	3	biochem	biochem	PROPN
fnp-3025	873	4	,	,	PUNCT
fnp-3025	873	5	2006	2006	NUM
fnp-3025	873	6	.	.	PUNCT
fnp-3025	874	1	75	75	NUM
fnp-3025	874	2	:	:	PUNCT
fnp-3025	875	1	p.	p.	NOUN
fnp-3025	875	2	333	333	NUM
fnp-3025	875	3	-	-	SYM
fnp-3025	875	4	66	66	NUM
fnp-3025	875	5	.	.	PUNCT
fnp-3025	875	6	57	57	NUM
fnp-3025	875	7	.	.	PUNCT
fnp-3025	876	1	fandrich	fandrich	PROPN
fnp-3025	876	2	,	,	PUNCT
fnp-3025	876	3	m.	m.	NOUN
fnp-3025	876	4	,	,	PUNCT
fnp-3025	876	5	on	on	ADP
fnp-3025	876	6	the	the	DET
fnp-3025	876	7	structural	structural	ADJ
fnp-3025	876	8	definition	definition	NOUN
fnp-3025	876	9	of	of	ADP
fnp-3025	876	10	amyloid	amyloid	NOUN
fnp-3025	876	11	fibrils	fibril	NOUN
fnp-3025	876	12	and	and	CCONJ
fnp-3025	876	13	other	other	ADJ
fnp-3025	876	14	polypeptide	polypeptide	ADJ
fnp-3025	876	15	aggregates	aggregate	NOUN
fnp-3025	876	16	.	.	PUNCT
fnp-3025	877	1	cell	cell	NOUN
fnp-3025	877	2	mol	mol	ADP
fnp-3025	877	3	life	life	PROPN
fnp-3025	877	4	sci	sci	PROPN
fnp-3025	877	5	,	,	PUNCT
fnp-3025	877	6	2007	2007	NUM
fnp-3025	877	7	.	.	PUNCT
fnp-3025	878	1	64(16	64(16	NUM
fnp-3025	878	2	):	):	PUNCT
fnp-3025	878	3	p.	p.	NOUN
fnp-3025	878	4	2066	2066	NUM
fnp-3025	878	5	-	-	SYM
fnp-3025	878	6	78	78	NUM
fnp-3025	878	7	.	.	PUNCT
fnp-3025	879	1	58	58	NUM
fnp-3025	879	2	.	.	PUNCT
fnp-3025	880	1	westermark	westermark	PROPN
fnp-3025	880	2	,	,	PUNCT
fnp-3025	880	3	g.t	g.t	PROPN
fnp-3025	880	4	.	.	PROPN
fnp-3025	880	5	,	,	PUNCT
fnp-3025	880	6	et	et	PROPN
fnp-3025	880	7	al	al	PROPN
fnp-3025	880	8	.	.	PROPN
fnp-3025	880	9	,	,	PUNCT
fnp-3025	880	10	noncerebral	noncerebral	ADJ
fnp-3025	880	11	amyloidoses	amyloidose	NOUN
fnp-3025	880	12	:	:	PUNCT
fnp-3025	880	13	aspects	aspect	NOUN
fnp-3025	880	14	on	on	ADP
fnp-3025	880	15	seeding	seeding	NOUN
fnp-3025	880	16	,	,	PUNCT
fnp-3025	880	17	cross	cross	ADJ
fnp-3025	880	18	-	-	ADJ
fnp-3025	880	19	seeding	seeding	ADJ
fnp-3025	880	20	,	,	PUNCT
fnp-3025	880	21	and	and	CCONJ
fnp-3025	880	22	transmission	transmission	NOUN
fnp-3025	880	23	.	.	PUNCT
fnp-3025	881	1	cold	cold	ADJ
fnp-3025	881	2	spring	spring	NOUN
fnp-3025	881	3	harb	harb	PROPN
fnp-3025	881	4	perspect	perspect	PROPN
fnp-3025	881	5	med	me	VERB
fnp-3025	881	6	,	,	PUNCT
fnp-3025	881	7	2018	2018	NUM
fnp-3025	881	8	.	.	PUNCT
fnp-3025	882	1	8(1	8(1	NOUN
fnp-3025	882	2	):	):	PUNCT
fnp-3025	882	3	p.	p.	PROPN
fnp-3025	882	4	a024323	a024323	PROPN
fnp-3025	882	5	.	.	PUNCT
fnp-3025	883	1	59	59	NUM
fnp-3025	883	2	.	.	PUNCT
fnp-3025	884	1	eisenberg	eisenberg	PROPN
fnp-3025	884	2	,	,	PUNCT
fnp-3025	884	3	d.	d.	PROPN
fnp-3025	884	4	and	and	CCONJ
fnp-3025	884	5	m.	m.	PROPN
fnp-3025	884	6	jucker	jucker	PROPN
fnp-3025	884	7	,	,	PUNCT
fnp-3025	884	8	the	the	DET
fnp-3025	884	9	amyloid	amyloid	NOUN
fnp-3025	884	10	state	state	NOUN
fnp-3025	884	11	of	of	ADP
fnp-3025	884	12	proteins	protein	NOUN
fnp-3025	884	13	in	in	ADP
fnp-3025	884	14	human	human	ADJ
fnp-3025	884	15	diseases	disease	NOUN
fnp-3025	884	16	.	.	PUNCT
fnp-3025	885	1	cell	cell	NOUN
fnp-3025	885	2	,	,	PUNCT
fnp-3025	885	3	2012	2012	NUM
fnp-3025	885	4	.	.	PUNCT
fnp-3025	886	1	148(6	148(6	NUM
fnp-3025	886	2	):	):	PUNCT
fnp-3025	887	1	p.	p.	NOUN
fnp-3025	887	2	1188	1188	NUM
fnp-3025	887	3	-	-	SYM
fnp-3025	887	4	203	203	NUM
fnp-3025	887	5	.	.	PUNCT
fnp-3025	887	6	60	60	NUM
fnp-3025	887	7	.	.	PUNCT
fnp-3025	888	1	hardy	hardy	ADJ
fnp-3025	888	2	,	,	PUNCT
fnp-3025	888	3	j.	j.	PROPN
fnp-3025	888	4	,	,	PUNCT
fnp-3025	888	5	expression	expression	NOUN
fnp-3025	888	6	of	of	ADP
fnp-3025	888	7	normal	normal	ADJ
fnp-3025	888	8	sequence	sequence	NOUN
fnp-3025	888	9	pathogenic	pathogenic	ADJ
fnp-3025	888	10	proteins	protein	NOUN
fnp-3025	888	11	for	for	ADP
fnp-3025	888	12	neurodegenerative	neurodegenerative	ADJ
fnp-3025	888	13	disease	disease	NOUN
fnp-3025	888	14	contributes	contribute	VERB
fnp-3025	888	15	to	to	ADP
fnp-3025	888	16	disease	disease	NOUN
fnp-3025	888	17	risk	risk	NOUN
fnp-3025	888	18	:	:	PUNCT
fnp-3025	888	19	‘	'	PUNCT
fnp-3025	888	20	permissive	permissive	ADJ
fnp-3025	888	21	templating	templating	NOUN
fnp-3025	888	22	’	'	PUNCT
fnp-3025	888	23	as	as	ADP
fnp-3025	888	24	a	a	DET
fnp-3025	888	25	general	general	ADJ
fnp-3025	888	26	mechanism	mechanism	NOUN
fnp-3025	888	27	underlying	underlie	VERB
fnp-3025	888	28	neurodegeneration	neurodegeneration	NOUN
fnp-3025	888	29	.	.	PUNCT
fnp-3025	889	1	biochem	biochem	PROPN
fnp-3025	889	2	soc	soc	PROPN
fnp-3025	889	3	trans	trans	PROPN
fnp-3025	889	4	,	,	PUNCT
fnp-3025	889	5	2005	2005	NUM
fnp-3025	889	6	.	.	PUNCT
fnp-3025	890	1	33(pt	33(pt	NUM
fnp-3025	890	2	4	4	NUM
fnp-3025	890	3	):	):	PUNCT
fnp-3025	890	4	p.	p.	NOUN
fnp-3025	890	5	578	578	NUM
fnp-3025	890	6	-	-	SYM
fnp-3025	890	7	81	81	NUM
fnp-3025	890	8	.	.	PUNCT
fnp-3025	890	9	61	61	NUM
fnp-3025	890	10	.	.	X
fnp-3025	891	1	annamalai	annamalai	PROPN
fnp-3025	891	2	,	,	PUNCT
fnp-3025	891	3	k.	k.	PROPN
fnp-3025	891	4	,	,	PUNCT
fnp-3025	891	5	et	et	PROPN
fnp-3025	891	6	al	al	PROPN
fnp-3025	891	7	.	.	PROPN
fnp-3025	891	8	,	,	PUNCT
fnp-3025	891	9	polymorphism	polymorphism	NOUN
fnp-3025	891	10	of	of	ADP
fnp-3025	891	11	amyloid	amyloid	NOUN
fnp-3025	891	12	fibrils	fibril	NOUN
fnp-3025	891	13	in	in	ADP
fnp-3025	891	14	vivo	vivo	NOUN
fnp-3025	891	15	.	.	PUNCT
fnp-3025	892	1	angew	angew	PROPN
fnp-3025	892	2	chem	chem	PROPN
fnp-3025	892	3	int	int	PROPN
fnp-3025	892	4	ed	ed	PROPN
fnp-3025	892	5	engl	engl	PROPN
fnp-3025	892	6	,	,	PUNCT
fnp-3025	892	7	2016	2016	NUM
fnp-3025	892	8	.	.	PUNCT
fnp-3025	893	1	55(15	55(15	NUM
fnp-3025	893	2	):	):	PUNCT
fnp-3025	893	3	p.	p.	NOUN
fnp-3025	893	4	4822	4822	NUM
fnp-3025	893	5	-	-	SYM
fnp-3025	893	6	5	5	NUM
fnp-3025	893	7	.	.	NUM
fnp-3025	893	8	62	62	NUM
fnp-3025	893	9	.	.	PUNCT
fnp-3025	894	1	eisenberg	eisenberg	PROPN
fnp-3025	894	2	,	,	PUNCT
fnp-3025	894	3	d.s	d.s	PROPN
fnp-3025	894	4	.	.	PROPN
fnp-3025	894	5	and	and	CCONJ
fnp-3025	894	6	m.r	m.r	PROPN
fnp-3025	894	7	.	.	PROPN
fnp-3025	894	8	sawaya	sawaya	PROPN
fnp-3025	894	9	,	,	PUNCT
fnp-3025	894	10	structural	structural	ADJ
fnp-3025	894	11	studies	study	NOUN
fnp-3025	894	12	of	of	ADP
fnp-3025	894	13	amyloid	amyloid	NOUN
fnp-3025	894	14	proteins	protein	NOUN
fnp-3025	894	15	at	at	ADP
fnp-3025	894	16	the	the	DET
fnp-3025	894	17	molecular	molecular	ADJ
fnp-3025	894	18	level	level	NOUN
fnp-3025	894	19	.	.	PUNCT
fnp-3025	895	1	annu	annu	PROPN
fnp-3025	895	2	rev	rev	VERB
fnp-3025	895	3	biochem	biochem	PROPN
fnp-3025	895	4	,	,	PUNCT
fnp-3025	895	5	2017	2017	NUM
fnp-3025	895	6	.	.	PUNCT
fnp-3025	896	1	86	86	NUM
fnp-3025	896	2	:	:	PUNCT
fnp-3025	897	1	p.	p.	NOUN
fnp-3025	897	2	69	69	NUM
fnp-3025	897	3	-	-	SYM
fnp-3025	897	4	95	95	NUM
fnp-3025	897	5	.	.	PUNCT
fnp-3025	898	1	63	63	NUM
fnp-3025	898	2	.	.	PUNCT
fnp-3025	899	1	fandrich	fandrich	PROPN
fnp-3025	899	2	,	,	PUNCT
fnp-3025	899	3	m.	m.	NOUN
fnp-3025	899	4	,	,	PUNCT
fnp-3025	899	5	j.	j.	PROPN
fnp-3025	899	6	meinhardt	meinhardt	PROPN
fnp-3025	899	7	,	,	PUNCT
fnp-3025	899	8	and	and	CCONJ
fnp-3025	899	9	n.	n.	PROPN
fnp-3025	899	10	grigorieff	grigorieff	PROPN
fnp-3025	899	11	,	,	PUNCT
fnp-3025	899	12	structural	structural	ADJ
fnp-3025	899	13	polymorphism	polymorphism	NOUN
fnp-3025	899	14	of	of	ADP
fnp-3025	899	15	alzheimer	alzheimer	PROPN
fnp-3025	899	16	abeta	abeta	PROPN
fnp-3025	899	17	and	and	CCONJ
fnp-3025	899	18	other	other	ADJ
fnp-3025	899	19	amyloid	amyloid	NOUN
fnp-3025	899	20	fibrils	fibril	NOUN
fnp-3025	899	21	.	.	PUNCT
fnp-3025	900	1	prion	prion	NOUN
fnp-3025	900	2	,	,	PUNCT
fnp-3025	900	3	2009	2009	NUM
fnp-3025	900	4	.	.	PUNCT
fnp-3025	901	1	3(2	3(2	NUM
fnp-3025	901	2	):	):	PUNCT
fnp-3025	902	1	p.	p.	NOUN
fnp-3025	902	2	89	89	NUM
fnp-3025	902	3	-	-	SYM
fnp-3025	902	4	93	93	NUM
fnp-3025	902	5	.	.	PUNCT
fnp-3025	903	1	64	64	NUM
fnp-3025	903	2	.	.	PUNCT
fnp-3025	904	1	fitzpatrick	fitzpatrick	PROPN
fnp-3025	904	2	,	,	PUNCT
fnp-3025	904	3	a.w.p	a.w.p	NOUN
fnp-3025	904	4	.	.	PUNCT
fnp-3025	904	5	,	,	PUNCT
fnp-3025	904	6	et	et	PROPN
fnp-3025	904	7	al	al	PROPN
fnp-3025	904	8	.	.	PROPN
fnp-3025	904	9	,	,	PUNCT
fnp-3025	904	10	cryo	cryo	PROPN
fnp-3025	904	11	-	-	PUNCT
fnp-3025	904	12	em	em	PRON
fnp-3025	904	13	structures	structure	NOUN
fnp-3025	904	14	of	of	ADP
fnp-3025	904	15	tau	tau	PROPN
fnp-3025	904	16	filaments	filament	NOUN
fnp-3025	904	17	from	from	ADP
fnp-3025	904	18	alzheimer	alzheimer	PROPN
fnp-3025	904	19	’s	’s	PART
fnp-3025	904	20	disease	disease	NOUN
fnp-3025	904	21	.	.	PUNCT
fnp-3025	905	1	nature	nature	NOUN
fnp-3025	905	2	,	,	PUNCT
fnp-3025	905	3	2017	2017	NUM
fnp-3025	905	4	.	.	PUNCT
fnp-3025	906	1	547(7662	547(7662	NUM
fnp-3025	906	2	):	):	PUNCT
fnp-3025	906	3	p.	p.	NOUN
fnp-3025	906	4	185	185	NUM
fnp-3025	906	5	-	-	SYM
fnp-3025	906	6	190	190	NUM
fnp-3025	906	7	.	.	PUNCT
fnp-3025	906	8	65	65	NUM
fnp-3025	906	9	.	.	PUNCT
fnp-3025	907	1	iadanza	iadanza	NOUN
fnp-3025	907	2	,	,	PUNCT
fnp-3025	907	3	m.g	m.g	PROPN
fnp-3025	907	4	.	.	PROPN
fnp-3025	907	5	,	,	PUNCT
fnp-3025	907	6	et	et	PROPN
fnp-3025	907	7	al	al	PROPN
fnp-3025	907	8	.	.	PROPN
fnp-3025	907	9	,	,	PUNCT
fnp-3025	907	10	the	the	DET
fnp-3025	907	11	structure	structure	NOUN
fnp-3025	907	12	of	of	ADP
fnp-3025	907	13	a	a	DET
fnp-3025	907	14	beta2	beta2	PROPN
fnp-3025	907	15	-	-	PUNCT
fnp-3025	907	16	microglobulin	microglobulin	PROPN
fnp-3025	907	17	fibril	fibril	PROPN
fnp-3025	907	18	suggests	suggest	VERB
fnp-3025	907	19	a	a	DET
fnp-3025	907	20	molecular	molecular	ADJ
fnp-3025	907	21	basis	basis	NOUN
fnp-3025	907	22	for	for	ADP
fnp-3025	907	23	its	its	PRON
fnp-3025	907	24	amyloid	amyloid	NOUN
fnp-3025	907	25	polymorphism	polymorphism	NOUN
fnp-3025	907	26	.	.	PUNCT
fnp-3025	908	1	nat	nat	PROPN
fnp-3025	908	2	commun	commun	PROPN
fnp-3025	908	3	,	,	PUNCT
fnp-3025	908	4	2018	2018	NUM
fnp-3025	908	5	.	.	PUNCT
fnp-3025	909	1	9(1	9(1	NUM
fnp-3025	909	2	):	):	PUNCT
fnp-3025	909	3	p.	p.	NOUN
fnp-3025	909	4	4517	4517	NUM
fnp-3025	909	5	.	.	PUNCT
fnp-3025	910	1	66	66	NUM
fnp-3025	910	2	.	.	PUNCT
fnp-3025	911	1	kollmer	kollmer	NOUN
fnp-3025	911	2	,	,	PUNCT
fnp-3025	911	3	m.	m.	NOUN
fnp-3025	911	4	,	,	PUNCT
fnp-3025	911	5	et	et	PROPN
fnp-3025	911	6	al	al	PROPN
fnp-3025	911	7	.	.	PROPN
fnp-3025	911	8	,	,	PUNCT
fnp-3025	911	9	cryo	cryo	PROPN
fnp-3025	911	10	-	-	PUNCT
fnp-3025	911	11	em	em	PROPN
fnp-3025	911	12	structure	structure	NOUN
fnp-3025	911	13	and	and	CCONJ
fnp-3025	911	14	polymorphism	polymorphism	NOUN
fnp-3025	911	15	of	of	ADP
fnp-3025	911	16	abeta	abeta	PROPN
fnp-3025	911	17	amyloid	amyloid	NOUN
fnp-3025	911	18	fibrils	fibril	NOUN
fnp-3025	911	19	purified	purify	VERB
fnp-3025	911	20	from	from	ADP
fnp-3025	911	21	alzheimer	alzheimer	PROPN
fnp-3025	911	22	’s	’s	PART
fnp-3025	911	23	brain	brain	NOUN
fnp-3025	911	24	tissue	tissue	NOUN
fnp-3025	911	25	.	.	PUNCT
fnp-3025	912	1	nat	nat	PROPN
fnp-3025	912	2	commun	commun	PROPN
fnp-3025	912	3	,	,	PUNCT
fnp-3025	912	4	2019	2019	NUM
fnp-3025	912	5	.	.	PUNCT
fnp-3025	913	1	10(1	10(1	NUM
fnp-3025	913	2	):	):	PUNCT
fnp-3025	913	3	p.	p.	NOUN
fnp-3025	913	4	4760	4760	NUM
fnp-3025	913	5	.	.	PUNCT
fnp-3025	914	1	67	67	NUM
fnp-3025	914	2	.	.	PUNCT
fnp-3025	915	1	petkova	petkova	PROPN
fnp-3025	915	2	,	,	PUNCT
fnp-3025	915	3	a.t	a.t	PROPN
fnp-3025	915	4	.	.	PROPN
fnp-3025	915	5	,	,	PUNCT
fnp-3025	915	6	et	et	PROPN
fnp-3025	915	7	al	al	PROPN
fnp-3025	915	8	.	.	PROPN
fnp-3025	915	9	,	,	PUNCT
fnp-3025	915	10	self	self	NOUN
fnp-3025	915	11	-	-	PUNCT
fnp-3025	915	12	propagating	propagate	VERB
fnp-3025	915	13	,	,	PUNCT
fnp-3025	915	14	molecular	molecular	ADJ
fnp-3025	915	15	-	-	PUNCT
fnp-3025	915	16	level	level	NOUN
fnp-3025	915	17	polymorphism	polymorphism	NOUN
fnp-3025	915	18	in	in	ADP
fnp-3025	915	19	alzheimer	alzheimer	PROPN
fnp-3025	915	20	’s	’s	PART
fnp-3025	915	21	beta	beta	NOUN
fnp-3025	915	22	-	-	PUNCT
fnp-3025	915	23	amyloid	amyloid	NOUN
fnp-3025	915	24	fibrils	fibril	NOUN
fnp-3025	915	25	.	.	PUNCT
fnp-3025	916	1	science	science	NOUN
fnp-3025	916	2	,	,	PUNCT
fnp-3025	916	3	2005	2005	NUM
fnp-3025	916	4	.	.	PUNCT
fnp-3025	917	1	307(5707	307(5707	NUM
fnp-3025	917	2	):	):	PUNCT
fnp-3025	917	3	p.	p.	NOUN
fnp-3025	917	4	262	262	NUM
fnp-3025	917	5	-	-	SYM
fnp-3025	917	6	5	5	NUM
fnp-3025	917	7	.	.	NUM
fnp-3025	917	8	68	68	NUM
fnp-3025	917	9	.	.	PUNCT
fnp-3025	918	1	roeder	roeder	PROPN
fnp-3025	918	2	,	,	PUNCT
fnp-3025	918	3	c.	c.	PROPN
fnp-3025	918	4	,	,	PUNCT
fnp-3025	918	5	et	et	PROPN
fnp-3025	918	6	al	al	PROPN
fnp-3025	918	7	.	.	PROPN
fnp-3025	918	8	,	,	PUNCT
fnp-3025	918	9	cryo	cryo	PROPN
fnp-3025	918	10	-	-	PUNCT
fnp-3025	918	11	em	em	PROPN
fnp-3025	918	12	structure	structure	NOUN
fnp-3025	918	13	of	of	ADP
fnp-3025	918	14	islet	islet	NOUN
fnp-3025	918	15	amyloid	amyloid	NOUN
fnp-3025	918	16	polypeptide	polypeptide	ADJ
fnp-3025	918	17	fibrils	fibril	NOUN
fnp-3025	918	18	reveals	reveal	VERB
fnp-3025	918	19	similarities	similarity	NOUN
fnp-3025	918	20	with	with	ADP
fnp-3025	918	21	amyloid	amyloid	NOUN
fnp-3025	918	22	-	-	PUNCT
fnp-3025	918	23	β	β	NOUN
fnp-3025	918	24	fibrils	fibril	NOUN
fnp-3025	918	25	.	.	PUNCT
fnp-3025	919	1	nat	nat	PROPN
fnp-3025	919	2	struct	struct	NOUN
fnp-3025	919	3	mol	mol	ADP
fnp-3025	919	4	biol	biol	PROPN
fnp-3025	919	5	,	,	PUNCT
fnp-3025	919	6	2020	2020	NUM
fnp-3025	919	7	.	.	PUNCT
fnp-3025	920	1	27(7	27(7	NOUN
fnp-3025	920	2	):	):	PUNCT
fnp-3025	921	1	p.	p.	NOUN
fnp-3025	921	2	660	660	NUM
fnp-3025	921	3	-	-	SYM
fnp-3025	921	4	667	667	NUM
fnp-3025	921	5	.	.	PUNCT
fnp-3025	921	6	69	69	NUM
fnp-3025	921	7	.	.	PUNCT
fnp-3025	922	1	pepys	pepys	PROPN
fnp-3025	922	2	,	,	PUNCT
fnp-3025	922	3	m.b	m.b	PROPN
fnp-3025	922	4	.	.	PROPN
fnp-3025	922	5	,	,	PUNCT
fnp-3025	922	6	pathogenesis	pathogenesis	NOUN
fnp-3025	922	7	,	,	PUNCT
fnp-3025	922	8	diagnosis	diagnosis	NOUN
fnp-3025	922	9	and	and	CCONJ
fnp-3025	922	10	treatment	treatment	NOUN
fnp-3025	922	11	of	of	ADP
fnp-3025	922	12	systemic	systemic	ADJ
fnp-3025	922	13	amyloidosis	amyloidosis	NOUN
fnp-3025	922	14	.	.	PUNCT
fnp-3025	923	1	philos	philos	PROPN
fnp-3025	923	2	trans	trans	PROPN
fnp-3025	923	3	r	r	PROPN
fnp-3025	923	4	soc	soc	PROPN
fnp-3025	923	5	lond	lond	PROPN
fnp-3025	923	6	b	b	PROPN
fnp-3025	923	7	biol	biol	PROPN
fnp-3025	923	8	sci	sci	PROPN
fnp-3025	923	9	,	,	PUNCT
fnp-3025	923	10	2001	2001	NUM
fnp-3025	923	11	.	.	PUNCT
fnp-3025	924	1	356(1406	356(1406	NUM
fnp-3025	924	2	):	):	PUNCT
fnp-3025	924	3	p.	p.	NOUN
fnp-3025	924	4	203	203	NUM
fnp-3025	924	5	-	-	SYM
fnp-3025	924	6	10	10	NUM
fnp-3025	924	7	;	;	PUNCT
fnp-3025	924	8	discussion	discussion	NOUN
fnp-3025	924	9	210	210	NUM
fnp-3025	924	10	-	-	SYM
fnp-3025	924	11	1	1	NUM
fnp-3025	924	12	.	.	NOUN
fnp-3025	924	13	70	70	NUM
fnp-3025	924	14	.	.	PUNCT
fnp-3025	925	1	pinney	pinney	NOUN
fnp-3025	925	2	,	,	PUNCT
fnp-3025	925	3	j.h	j.h	PROPN
fnp-3025	925	4	.	.	PROPN
fnp-3025	925	5	and	and	CCONJ
fnp-3025	925	6	p.n	p.n	PROPN
fnp-3025	925	7	.	.	PROPN
fnp-3025	925	8	hawkins	hawkins	PROPN
fnp-3025	925	9	,	,	PUNCT
fnp-3025	925	10	amyloidosis	amyloidosis	NOUN
fnp-3025	925	11	.	.	PUNCT
fnp-3025	926	1	ann	ann	PROPN
fnp-3025	926	2	clin	clin	PROPN
fnp-3025	926	3	biochem	biochem	PROPN
fnp-3025	926	4	,	,	PUNCT
fnp-3025	926	5	2012	2012	NUM
fnp-3025	926	6	.	.	PUNCT
fnp-3025	927	1	49(pt	49(pt	NUM
fnp-3025	928	1	3	3	NUM
fnp-3025	928	2	):	):	PUNCT
fnp-3025	928	3	p.	p.	NOUN
fnp-3025	928	4	229	229	NUM
fnp-3025	928	5	-	-	SYM
fnp-3025	928	6	41	41	NUM
fnp-3025	928	7	.	.	PUNCT
fnp-3025	929	1	71	71	NUM
fnp-3025	929	2	.	.	PUNCT
fnp-3025	930	1	bridger	bridger	PROPN
fnp-3025	930	2	,	,	PUNCT
fnp-3025	930	3	j.	j.	PROPN
fnp-3025	930	4	and	and	CCONJ
fnp-3025	930	5	n.a	n.a	PROPN
fnp-3025	930	6	.	.	PROPN
fnp-3025	930	7	wright	wright	PROPN
fnp-3025	930	8	,	,	PUNCT
fnp-3025	930	9	amyloidosis	amyloidosis	NOUN
fnp-3025	930	10	,	,	PUNCT
fnp-3025	930	11	in	in	ADP
fnp-3025	930	12	oxford	oxford	PROPN
fnp-3025	930	13	textbook	textbook	NOUN
fnp-3025	930	14	of	of	ADP
fnp-3025	930	15	pathology	pathology	NOUN
fnp-3025	930	16	,	,	PUNCT
fnp-3025	930	17	j.o.d	j.o.d	PROPN
fnp-3025	930	18	.	.	PUNCT
fnp-3025	931	1	mcgee	mcgee	PROPN
fnp-3025	931	2	,	,	PUNCT
fnp-3025	931	3	p.g	p.g	PROPN
fnp-3025	931	4	.	.	PROPN
fnp-3025	931	5	isaacson	isaacson	PROPN
fnp-3025	931	6	,	,	PUNCT
fnp-3025	931	7	and	and	CCONJ
fnp-3025	931	8	n.a	n.a	PROPN
fnp-3025	931	9	.	.	PROPN
fnp-3025	931	10	wright	wright	PROPN
fnp-3025	931	11	,	,	PUNCT
fnp-3025	931	12	editors	editor	NOUN
fnp-3025	931	13	.	.	PUNCT
fnp-3025	931	14	1992	1992	NUM
fnp-3025	931	15	,	,	PUNCT
fnp-3025	931	16	oxford	oxford	PROPN
fnp-3025	931	17	university	university	PROPN
fnp-3025	931	18	press	press	NOUN
fnp-3025	931	19	:	:	PUNCT
fnp-3025	931	20	new	new	PROPN
fnp-3025	931	21	york	york	PROPN
fnp-3025	931	22	.	.	PUNCT
fnp-3025	932	1	p.	p.	NOUN
fnp-3025	932	2	406	406	NUM
fnp-3025	932	3	-	-	SYM
fnp-3025	932	4	412	412	NUM
fnp-3025	932	5	.	.	PUNCT
fnp-3025	932	6	72	72	NUM
fnp-3025	932	7	.	.	PUNCT
fnp-3025	933	1	chen	chen	PROPN
fnp-3025	933	2	,	,	PUNCT
fnp-3025	933	3	d.	d.	PROPN
fnp-3025	933	4	,	,	PUNCT
fnp-3025	933	5	et	et	PROPN
fnp-3025	933	6	al	al	PROPN
fnp-3025	933	7	.	.	PROPN
fnp-3025	933	8	,	,	PUNCT
fnp-3025	933	9	tau	tau	PROPN
fnp-3025	933	10	local	local	ADJ
fnp-3025	933	11	structure	structure	NOUN
fnp-3025	933	12	shields	shield	VERB
fnp-3025	933	13	an	an	DET
fnp-3025	933	14	amyloid	amyloid	NOUN
fnp-3025	933	15	-	-	PUNCT
fnp-3025	933	16	forming	form	VERB
fnp-3025	933	17	motif	motif	NOUN
fnp-3025	933	18	and	and	CCONJ
fnp-3025	933	19	controls	control	VERB
fnp-3025	933	20	aggregation	aggregation	NOUN
fnp-3025	933	21	propensity	propensity	NOUN
fnp-3025	933	22	.	.	PUNCT
fnp-3025	934	1	nat	nat	PROPN
fnp-3025	934	2	commun	commun	PROPN
fnp-3025	934	3	,	,	PUNCT
fnp-3025	934	4	2019	2019	NUM
fnp-3025	934	5	.	.	PUNCT
fnp-3025	935	1	10(1	10(1	NUM
fnp-3025	935	2	):	):	PUNCT
fnp-3025	935	3	p.	p.	NOUN
fnp-3025	935	4	2493	2493	NUM
fnp-3025	935	5	.	.	PUNCT
fnp-3025	936	1	73	73	NUM
fnp-3025	936	2	.	.	PUNCT
fnp-3025	936	3	arriagada	arriagada	PROPN
fnp-3025	936	4	,	,	PUNCT
fnp-3025	936	5	p.v	p.v	PROPN
fnp-3025	936	6	.	.	PROPN
fnp-3025	936	7	,	,	PUNCT
fnp-3025	936	8	et	et	PROPN
fnp-3025	936	9	al	al	PROPN
fnp-3025	936	10	.	.	PROPN
fnp-3025	936	11	,	,	PUNCT
fnp-3025	936	12	neurofibrillary	neurofibrillary	ADJ
fnp-3025	936	13	tangles	tangle	NOUN
fnp-3025	936	14	but	but	CCONJ
fnp-3025	936	15	not	not	PART
fnp-3025	936	16	senile	senile	ADJ
fnp-3025	936	17	plaques	plaque	NOUN
fnp-3025	936	18	parallel	parallel	ADJ
fnp-3025	936	19	duration	duration	NOUN
fnp-3025	936	20	and	and	CCONJ
fnp-3025	936	21	severity	severity	NOUN
fnp-3025	936	22	of	of	ADP
fnp-3025	936	23	alzheimer	alzheimer	PROPN
fnp-3025	936	24	’s	’s	PART
fnp-3025	936	25	disease	disease	NOUN
fnp-3025	936	26	.	.	PUNCT
fnp-3025	937	1	neurology	neurology	NOUN
fnp-3025	937	2	,	,	PUNCT
fnp-3025	937	3	1992	1992	NUM
fnp-3025	937	4	.	.	PUNCT
fnp-3025	938	1	42(3	42(3	NUM
fnp-3025	938	2	pt	pt	NOUN
fnp-3025	938	3	1	1	NUM
fnp-3025	938	4	):	):	PUNCT
fnp-3025	938	5	p.	p.	NOUN
fnp-3025	938	6	631	631	NUM
fnp-3025	938	7	-	-	SYM
fnp-3025	938	8	9	9	NUM
fnp-3025	938	9	.	.	X
fnp-3025	938	10	74	74	NUM
fnp-3025	939	1	.	.	PUNCT
fnp-3025	939	2	bierer	bierer	NOUN
fnp-3025	939	3	,	,	PUNCT
fnp-3025	939	4	l.m	l.m	PROPN
fnp-3025	939	5	.	.	PROPN
fnp-3025	939	6	,	,	PUNCT
fnp-3025	939	7	et	et	PROPN
fnp-3025	939	8	al	al	PROPN
fnp-3025	939	9	.	.	PROPN
fnp-3025	939	10	,	,	PUNCT
fnp-3025	939	11	neocortical	neocortical	ADJ
fnp-3025	939	12	neurofibrillary	neurofibrillary	ADJ
fnp-3025	939	13	tangles	tangle	NOUN
fnp-3025	939	14	correlate	correlate	VERB
fnp-3025	939	15	with	with	ADP
fnp-3025	939	16	dementia	dementia	NOUN
fnp-3025	939	17	severity	severity	NOUN
fnp-3025	939	18	in	in	ADP
fnp-3025	939	19	alzheimer	alzheimer	PROPN
fnp-3025	939	20	’s	’s	PART
fnp-3025	939	21	disease	disease	NOUN
fnp-3025	939	22	.	.	PUNCT
fnp-3025	940	1	arch	arch	ADJ
fnp-3025	940	2	neurol	neurol	NOUN
fnp-3025	940	3	,	,	PUNCT
fnp-3025	940	4	1995	1995	NUM
fnp-3025	940	5	.	.	PUNCT
fnp-3025	941	1	52(1	52(1	NUM
fnp-3025	941	2	):	):	PUNCT
fnp-3025	941	3	p.	p.	NOUN
fnp-3025	941	4	81	81	NUM
fnp-3025	941	5	-	-	SYM
fnp-3025	941	6	8	8	NUM
fnp-3025	941	7	.	.	X
fnp-3025	942	1	75	75	NUM
fnp-3025	942	2	.	.	PUNCT
fnp-3025	943	1	crystal	crystal	PROPN
fnp-3025	943	2	,	,	PUNCT
fnp-3025	943	3	h.	h.	PROPN
fnp-3025	943	4	,	,	PUNCT
fnp-3025	943	5	et	et	PROPN
fnp-3025	943	6	al	al	PROPN
fnp-3025	943	7	.	.	PROPN
fnp-3025	943	8	,	,	PUNCT
fnp-3025	943	9	clinico	clinico	ADJ
fnp-3025	943	10	-	-	PUNCT
fnp-3025	943	11	pathologic	pathologic	ADJ
fnp-3025	943	12	studies	study	NOUN
fnp-3025	943	13	in	in	ADP
fnp-3025	943	14	dementia	dementia	PROPN
fnp-3025	943	15	:	:	PUNCT
fnp-3025	943	16	nondemented	nondemente	VERB
fnp-3025	943	17	subjects	subject	NOUN
fnp-3025	943	18	with	with	ADP
fnp-3025	943	19	pathologically	pathologically	ADV
fnp-3025	943	20	confirmed	confirm	VERB
fnp-3025	943	21	alzheimer	alzheimer	PROPN
fnp-3025	943	22	’s	’s	PART
fnp-3025	943	23	disease	disease	NOUN
fnp-3025	943	24	.	.	PUNCT
fnp-3025	944	1	neurology	neurology	NOUN
fnp-3025	944	2	,	,	PUNCT
fnp-3025	944	3	1988	1988	NUM
fnp-3025	944	4	.	.	PUNCT
fnp-3025	945	1	38(11	38(11	NUM
fnp-3025	945	2	):	):	PUNCT
fnp-3025	945	3	p.	p.	NOUN
fnp-3025	945	4	1682	1682	NUM
fnp-3025	945	5	-	-	SYM
fnp-3025	945	6	7	7	NUM
fnp-3025	945	7	.	.	NUM
fnp-3025	945	8	76	76	NUM
fnp-3025	945	9	.	.	PUNCT
fnp-3025	946	1	gold	gold	NOUN
fnp-3025	946	2	,	,	PUNCT
fnp-3025	946	3	g.	g.	PROPN
fnp-3025	946	4	,	,	PUNCT
fnp-3025	946	5	et	et	PROPN
fnp-3025	946	6	al	al	PROPN
fnp-3025	946	7	.	.	PROPN
fnp-3025	946	8	,	,	PUNCT
fnp-3025	946	9	clinical	clinical	ADJ
fnp-3025	946	10	validity	validity	NOUN
fnp-3025	946	11	of	of	ADP
fnp-3025	946	12	a	a	DET
fnp-3025	946	13	beta	beta	NOUN
fnp-3025	946	14	-	-	PUNCT
fnp-3025	946	15	protein	protein	NOUN
fnp-3025	946	16	deposition	deposition	NOUN
fnp-3025	946	17	staging	staging	NOUN
fnp-3025	946	18	in	in	ADP
fnp-3025	946	19	brain	brain	NOUN
fnp-3025	946	20	aging	aging	NOUN
fnp-3025	946	21	and	and	CCONJ
fnp-3025	946	22	alzheimer	alzheimer	NOUN
fnp-3025	946	23	disease	disease	NOUN
fnp-3025	946	24	.	.	PUNCT
fnp-3025	947	1	j	j	PROPN
fnp-3025	947	2	neuropathol	neuropathol	PROPN
fnp-3025	947	3	exp	exp	PROPN
fnp-3025	947	4	neurol	neurol	PROPN
fnp-3025	947	5	,	,	PUNCT
fnp-3025	947	6	2001	2001	NUM
fnp-3025	947	7	.	.	PUNCT
fnp-3025	948	1	60(10	60(10	NUM
fnp-3025	948	2	):	):	PUNCT
fnp-3025	948	3	p.	p.	NOUN
fnp-3025	948	4	946	946	NUM
fnp-3025	948	5	-	-	SYM
fnp-3025	948	6	52	52	NUM
fnp-3025	948	7	.	.	PUNCT
fnp-3025	949	1	77	77	NUM
fnp-3025	949	2	.	.	PUNCT
fnp-3025	950	1	nagy	nagy	PROPN
fnp-3025	950	2	,	,	PUNCT
fnp-3025	950	3	z.	z.	PROPN
fnp-3025	950	4	,	,	PUNCT
fnp-3025	950	5	et	et	PROPN
fnp-3025	950	6	al	al	PROPN
fnp-3025	950	7	.	.	PROPN
fnp-3025	950	8	,	,	PUNCT
fnp-3025	950	9	relative	relative	ADJ
fnp-3025	950	10	roles	role	NOUN
fnp-3025	950	11	of	of	ADP
fnp-3025	950	12	plaques	plaque	NOUN
fnp-3025	950	13	and	and	CCONJ
fnp-3025	950	14	tangles	tangle	NOUN
fnp-3025	950	15	in	in	ADP
fnp-3025	950	16	the	the	DET
fnp-3025	950	17	dementia	dementia	NOUN
fnp-3025	950	18	of	of	ADP
fnp-3025	950	19	alzheimer	alzheimer	PROPN
fnp-3025	950	20	’s	’s	PART
fnp-3025	950	21	disease	disease	NOUN
fnp-3025	950	22	:	:	PUNCT
fnp-3025	950	23	correlations	correlation	NOUN
fnp-3025	950	24	using	use	VERB
fnp-3025	950	25	three	three	NUM
fnp-3025	950	26	sets	set	NOUN
fnp-3025	950	27	of	of	ADP
fnp-3025	950	28	neuropathological	neuropathological	ADJ
fnp-3025	950	29	criteria	criterion	NOUN
fnp-3025	950	30	.	.	PUNCT
fnp-3025	951	1	dementia	dementia	NOUN
fnp-3025	951	2	,	,	PUNCT
fnp-3025	951	3	1995	1995	NUM
fnp-3025	951	4	.	.	PUNCT
fnp-3025	952	1	6(1	6(1	NUM
fnp-3025	952	2	):	):	PUNCT
fnp-3025	953	1	p.	p.	NOUN
fnp-3025	953	2	21	21	NUM
fnp-3025	953	3	-	-	SYM
fnp-3025	953	4	31	31	NUM
fnp-3025	953	5	.	.	PUNCT
fnp-3025	954	1	78	78	NUM
fnp-3025	954	2	.	.	PUNCT
fnp-3025	955	1	wilcock	wilcock	PROPN
fnp-3025	955	2	,	,	PUNCT
fnp-3025	955	3	g.k	g.k	PROPN
fnp-3025	955	4	.	.	PROPN
fnp-3025	955	5	and	and	CCONJ
fnp-3025	955	6	m.m	m.m	PROPN
fnp-3025	955	7	.	.	PROPN
fnp-3025	955	8	esiri	esiri	PROPN
fnp-3025	955	9	,	,	PUNCT
fnp-3025	955	10	plaques	plaque	NOUN
fnp-3025	955	11	,	,	PUNCT
fnp-3025	955	12	tangles	tangle	NOUN
fnp-3025	955	13	and	and	CCONJ
fnp-3025	955	14	dementia	dementia	NOUN
fnp-3025	955	15	.	.	PUNCT
fnp-3025	956	1	a	a	DET
fnp-3025	956	2	quantitative	quantitative	ADJ
fnp-3025	956	3	study	study	NOUN
fnp-3025	956	4	.	.	PUNCT
fnp-3025	957	1	j	j	PROPN
fnp-3025	957	2	neurol	neurol	PROPN
fnp-3025	957	3	sci	sci	PROPN
fnp-3025	957	4	,	,	PUNCT
fnp-3025	957	5	1982	1982	NUM
fnp-3025	957	6	.	.	PUNCT
fnp-3025	958	1	56(2	56(2	NUM
fnp-3025	958	2	-	-	PUNCT
fnp-3025	958	3	3	3	NUM
fnp-3025	958	4	):	):	PUNCT
fnp-3025	958	5	p.	p.	NOUN
fnp-3025	958	6	343	343	NUM
fnp-3025	958	7	-	-	SYM
fnp-3025	958	8	56	56	NUM
fnp-3025	958	9	.	.	NOUN
fnp-3025	958	10	79	79	NUM
fnp-3025	958	11	.	.	PUNCT
fnp-3025	959	1	braak	braak	PROPN
fnp-3025	959	2	,	,	PUNCT
fnp-3025	959	3	h.	h.	PROPN
fnp-3025	959	4	and	and	CCONJ
fnp-3025	959	5	e.	e.	PROPN
fnp-3025	959	6	braak	braak	PROPN
fnp-3025	959	7	,	,	PUNCT
fnp-3025	959	8	neuropathological	neuropathological	ADJ
fnp-3025	959	9	stageing	stageing	NOUN
fnp-3025	959	10	of	of	ADP
fnp-3025	959	11	alzheimer	alzheimer	NOUN
fnp-3025	959	12	-	-	PUNCT
fnp-3025	959	13	related	relate	VERB
fnp-3025	959	14	changes	change	NOUN
fnp-3025	959	15	.	.	PUNCT
fnp-3025	960	1	acta	acta	PROPN
fnp-3025	960	2	neuropathol	neuropathol	PROPN
fnp-3025	960	3	,	,	PUNCT
fnp-3025	960	4	1991	1991	NUM
fnp-3025	960	5	.	.	PUNCT
fnp-3025	961	1	82(4	82(4	NUM
fnp-3025	961	2	):	):	PUNCT
fnp-3025	962	1	p.	p.	NOUN
fnp-3025	962	2	239	239	NUM
fnp-3025	962	3	-	-	SYM
fnp-3025	962	4	59	59	NUM
fnp-3025	962	5	.	.	PUNCT
fnp-3025	962	6	80	80	NUM
fnp-3025	962	7	.	.	PUNCT
fnp-3025	963	1	braak	braak	PROPN
fnp-3025	963	2	,	,	PUNCT
fnp-3025	963	3	h.	h.	PROPN
fnp-3025	963	4	and	and	CCONJ
fnp-3025	963	5	e.	e.	PROPN
fnp-3025	963	6	braak	braak	PROPN
fnp-3025	963	7	,	,	PUNCT
fnp-3025	963	8	frequency	frequency	NOUN
fnp-3025	963	9	of	of	ADP
fnp-3025	963	10	stages	stage	NOUN
fnp-3025	963	11	of	of	ADP
fnp-3025	963	12	alzheimer	alzheimer	NOUN
fnp-3025	963	13	-	-	PUNCT
fnp-3025	963	14	related	relate	VERB
fnp-3025	963	15	lesions	lesion	NOUN
fnp-3025	963	16	in	in	ADP
fnp-3025	963	17	different	different	ADJ
fnp-3025	963	18	age	age	NOUN
fnp-3025	963	19	categories	category	NOUN
fnp-3025	963	20	.	.	PUNCT
fnp-3025	964	1	neurobiol	neurobiol	PROPN
fnp-3025	964	2	aging	aging	NOUN
fnp-3025	964	3	,	,	PUNCT
fnp-3025	964	4	1997	1997	NUM
fnp-3025	964	5	.	.	PUNCT
fnp-3025	965	1	18(4	18(4	NUM
fnp-3025	965	2	):	):	PUNCT
fnp-3025	965	3	p.	p.	NOUN
fnp-3025	965	4	351	351	NUM
fnp-3025	965	5	-	-	SYM
fnp-3025	965	6	7	7	NUM
fnp-3025	965	7	.	.	NUM
fnp-3025	965	8	81	81	NUM
fnp-3025	965	9	.	.	PUNCT
fnp-3025	966	1	tomlinson	tomlinson	PROPN
fnp-3025	966	2	,	,	PUNCT
fnp-3025	966	3	b.e	b.e	PROPN
fnp-3025	966	4	.	.	PROPN
fnp-3025	966	5	and	and	CCONJ
fnp-3025	966	6	j.a.n	j.a.n	PROPN
fnp-3025	966	7	.	.	PUNCT
fnp-3025	966	8	corsellis	corsellis	PROPN
fnp-3025	966	9	,	,	PUNCT
fnp-3025	966	10	ageing	ageing	NOUN
fnp-3025	966	11	and	and	CCONJ
fnp-3025	966	12	the	the	DET
fnp-3025	966	13	dementias	dementia	NOUN
fnp-3025	966	14	,	,	PUNCT
fnp-3025	966	15	in	in	ADP
fnp-3025	966	16	greenfield	greenfield	NOUN
fnp-3025	966	17	’s	’s	PART
fnp-3025	966	18	neuropathology	neuropathology	NOUN
fnp-3025	966	19	,	,	PUNCT
fnp-3025	966	20	j.h	j.h	PROPN
fnp-3025	966	21	.	.	PROPN
fnp-3025	966	22	adams	adams	PROPN
fnp-3025	966	23	,	,	PUNCT
fnp-3025	966	24	j.a.n	j.a.n	PROPN
fnp-3025	966	25	.	.	PUNCT
fnp-3025	966	26	corsellis	corsellis	PROPN
fnp-3025	966	27	,	,	PUNCT
fnp-3025	966	28	and	and	CCONJ
fnp-3025	967	1	l.w	l.w	PROPN
fnp-3025	967	2	.	.	PROPN
fnp-3025	967	3	duchen	duchen	PROPN
fnp-3025	967	4	,	,	PUNCT
fnp-3025	967	5	editors	editor	NOUN
fnp-3025	967	6	.	.	PUNCT
fnp-3025	968	1	1984	1984	NUM
fnp-3025	968	2	,	,	PUNCT
fnp-3025	968	3	john	john	PROPN
fnp-3025	968	4	wiley	wiley	PROPN
fnp-3025	968	5	and	and	CCONJ
fnp-3025	968	6	sons	son	NOUN
fnp-3025	968	7	:	:	PUNCT
fnp-3025	968	8	new	new	PROPN
fnp-3025	968	9	york	york	PROPN
fnp-3025	968	10	.	.	PUNCT
fnp-3025	969	1	p.	p.	NOUN
fnp-3025	969	2	951	951	NUM
fnp-3025	969	3	-	-	SYM
fnp-3025	969	4	1025	1025	NUM
fnp-3025	969	5	.	.	PUNCT
fnp-3025	970	1	82	82	NUM
fnp-3025	970	2	.	.	PUNCT
fnp-3025	971	1	he	he	PRON
fnp-3025	971	2	,	,	PUNCT
fnp-3025	971	3	z.	z.	PROPN
fnp-3025	971	4	,	,	PUNCT
fnp-3025	971	5	et	et	PROPN
fnp-3025	971	6	al	al	PROPN
fnp-3025	971	7	.	.	PROPN
fnp-3025	971	8	,	,	PUNCT
fnp-3025	971	9	amyloid	amyloid	NOUN
fnp-3025	971	10	-	-	PUNCT
fnp-3025	971	11	beta	beta	NOUN
fnp-3025	971	12	plaques	plaque	NOUN
fnp-3025	971	13	enhance	enhance	VERB
fnp-3025	971	14	alzheimer	alzheimer	PROPN
fnp-3025	971	15	’s	’s	PART
fnp-3025	971	16	brain	brain	NOUN
fnp-3025	971	17	tau	tau	NOUN
fnp-3025	971	18	-	-	PUNCT
fnp-3025	971	19	seeded	seed	VERB
fnp-3025	971	20	pathologies	pathology	NOUN
fnp-3025	971	21	by	by	ADP
fnp-3025	971	22	facilitating	facilitate	VERB
fnp-3025	971	23	neuritic	neuritic	ADJ
fnp-3025	971	24	plaque	plaque	NOUN
fnp-3025	971	25	tau	tau	PROPN
fnp-3025	971	26	aggregation	aggregation	NOUN
fnp-3025	971	27	.	.	PUNCT
fnp-3025	972	1	nat	nat	PROPN
fnp-3025	972	2	med	med	PROPN
fnp-3025	972	3	,	,	PUNCT
fnp-3025	972	4	2018	2018	NUM
fnp-3025	972	5	.	.	PUNCT
fnp-3025	973	1	24(1	24(1	NUM
fnp-3025	973	2	):	):	PUNCT
fnp-3025	973	3	p.	p.	NOUN
fnp-3025	973	4	29	29	NUM
fnp-3025	973	5	-	-	SYM
fnp-3025	973	6	38	38	NUM
fnp-3025	973	7	.	.	PUNCT
fnp-3025	973	8	83	83	NUM
fnp-3025	973	9	.	.	PUNCT
fnp-3025	974	1	stancu	stancu	PROPN
fnp-3025	974	2	,	,	PUNCT
fnp-3025	974	3	i.c	i.c	PROPN
fnp-3025	974	4	.	.	PROPN
fnp-3025	974	5	,	,	PUNCT
fnp-3025	974	6	et	et	PROPN
fnp-3025	974	7	al	al	PROPN
fnp-3025	974	8	.	.	PROPN
fnp-3025	974	9	,	,	PUNCT
fnp-3025	974	10	models	model	NOUN
fnp-3025	974	11	of	of	ADP
fnp-3025	974	12	beta	beta	NOUN
fnp-3025	974	13	-	-	PUNCT
fnp-3025	974	14	amyloid	amyloid	NOUN
fnp-3025	974	15	induced	induce	VERB
fnp-3025	974	16	tau	tau	NOUN
fnp-3025	974	17	-	-	PUNCT
fnp-3025	974	18	pathology	pathology	NOUN
fnp-3025	974	19	:	:	PUNCT
fnp-3025	974	20	the	the	DET
fnp-3025	974	21	long	long	ADJ
fnp-3025	974	22	and	and	CCONJ
fnp-3025	974	23	"	"	PUNCT
fnp-3025	974	24	folded	folded	ADJ
fnp-3025	974	25	"	"	PUNCT
fnp-3025	974	26	road	road	NOUN
fnp-3025	974	27	to	to	PART
fnp-3025	974	28	understand	understand	VERB
fnp-3025	974	29	the	the	DET
fnp-3025	974	30	mechanism	mechanism	NOUN
fnp-3025	974	31	.	.	PUNCT
fnp-3025	975	1	mol	mol	ADP
fnp-3025	975	2	neurodegener	neurodegener	NOUN
fnp-3025	975	3	,	,	PUNCT
fnp-3025	975	4	2014	2014	NUM
fnp-3025	975	5	.	.	PUNCT
fnp-3025	976	1	9	9	NUM
fnp-3025	976	2	:	:	PUNCT
fnp-3025	976	3	p.	p.	NOUN
fnp-3025	976	4	51	51	NUM
fnp-3025	976	5	.	.	PUNCT
fnp-3025	976	6	84	84	NUM
fnp-3025	976	7	.	.	PUNCT
fnp-3025	977	1	busche	busche	NOUN
fnp-3025	977	2	,	,	PUNCT
fnp-3025	977	3	m.a	m.a	PROPN
fnp-3025	977	4	.	.	PROPN
fnp-3025	977	5	and	and	CCONJ
fnp-3025	977	6	b.t	b.t	PROPN
fnp-3025	977	7	.	.	PROPN
fnp-3025	977	8	hyman	hyman	PROPN
fnp-3025	977	9	,	,	PUNCT
fnp-3025	977	10	synergy	synergy	NOUN
fnp-3025	977	11	between	between	ADP
fnp-3025	977	12	amyloid	amyloid	NOUN
fnp-3025	977	13	-	-	PUNCT
fnp-3025	977	14	beta	beta	NOUN
fnp-3025	977	15	and	and	CCONJ
fnp-3025	977	16	tau	tau	PROPN
fnp-3025	977	17	in	in	ADP
fnp-3025	977	18	alzheimer	alzheimer	PROPN
fnp-3025	977	19	’s	’s	PART
fnp-3025	977	20	disease	disease	NOUN
fnp-3025	977	21	.	.	PUNCT
fnp-3025	978	1	nat	nat	PROPN
fnp-3025	978	2	neurosci	neurosci	PROPN
fnp-3025	978	3	,	,	PUNCT
fnp-3025	978	4	2020	2020	NUM
fnp-3025	978	5	.	.	PUNCT
fnp-3025	979	1	23(10	23(10	NUM
fnp-3025	979	2	):	):	PUNCT
fnp-3025	979	3	p.	p.	NOUN
fnp-3025	979	4	1183	1183	NUM
fnp-3025	979	5	-	-	SYM
fnp-3025	979	6	1193	1193	NUM
fnp-3025	979	7	.	.	PUNCT
fnp-3025	979	8	85	85	NUM
fnp-3025	979	9	.	.	PUNCT
fnp-3025	980	1	cook	cook	VERB
fnp-3025	980	2	,	,	PUNCT
fnp-3025	980	3	h.c	h.c	PROPN
fnp-3025	980	4	.	.	PROPN
fnp-3025	980	5	,	,	PUNCT
fnp-3025	980	6	origins	origin	NOUN
fnp-3025	980	7	of	of	ADP
fnp-3025	980	8	...	...	PUNCT
fnp-3025	980	9	tinctorial	tinctorial	ADJ
fnp-3025	980	10	methods	method	NOUN
fnp-3025	980	11	in	in	ADP
fnp-3025	980	12	histology	histology	NOUN
fnp-3025	980	13	.	.	PUNCT
fnp-3025	981	1	j	j	PROPN
fnp-3025	981	2	clin	clin	PROPN
fnp-3025	981	3	pathol	pathol	PROPN
fnp-3025	981	4	,	,	PUNCT
fnp-3025	981	5	1997	1997	NUM
fnp-3025	981	6	.	.	PUNCT
fnp-3025	982	1	50(9	50(9	NUM
fnp-3025	982	2	):	):	PUNCT
fnp-3025	982	3	p.	p.	NOUN
fnp-3025	982	4	716	716	NUM
fnp-3025	982	5	-	-	SYM
fnp-3025	982	6	20	20	NUM
fnp-3025	982	7	.	.	PUNCT
fnp-3025	983	1	86	86	NUM
fnp-3025	983	2	.	.	PUNCT
fnp-3025	983	3	blocq	blocq	NOUN
fnp-3025	983	4	,	,	PUNCT
fnp-3025	983	5	p.	p.	NOUN
fnp-3025	983	6	and	and	CCONJ
fnp-3025	983	7	g.	g.	PROPN
fnp-3025	983	8	marinesco	marinesco	PROPN
fnp-3025	983	9	,	,	PUNCT
fnp-3025	983	10	sur	sur	PROPN
fnp-3025	983	11	les	les	PROPN
fnp-3025	983	12	lésions	lésion	NOUN
fnp-3025	983	13	et	et	PROPN
fnp-3025	983	14	la	la	PROPN
fnp-3025	983	15	pathogénie	pathogénie	PROPN
fnp-3025	983	16	de	de	PROPN
fnp-3025	983	17	l’épilepsie	l’épilepsie	X
fnp-3025	983	18	dite	dite	PROPN
fnp-3025	983	19	essentielle	essentielle	X
fnp-3025	983	20	.	.	PUNCT
fnp-3025	984	1	la	la	PROPN
fnp-3025	984	2	semaine	semaine	PROPN
fnp-3025	984	3	médicale	médicale	PROPN
fnp-3025	984	4	,	,	PUNCT
fnp-3025	984	5	1892	1892	NUM
fnp-3025	984	6	.	.	PUNCT
fnp-3025	985	1	p.	p.	NOUN
fnp-3025	985	2	445	445	NUM
fnp-3025	986	1	-	-	SYM
fnp-3025	986	2	446	446	NUM
fnp-3025	986	3	.	.	PUNCT
fnp-3025	987	1	87	87	NUM
fnp-3025	987	2	.	.	PUNCT
fnp-3025	988	1	goedert	goedert	NOUN
fnp-3025	988	2	,	,	PUNCT
fnp-3025	988	3	m.	m.	NOUN
fnp-3025	988	4	,	,	PUNCT
fnp-3025	988	5	oskar	oskar	PROPN
fnp-3025	988	6	fischer	fischer	PROPN
fnp-3025	988	7	and	and	CCONJ
fnp-3025	988	8	the	the	DET
fnp-3025	988	9	study	study	NOUN
fnp-3025	988	10	of	of	ADP
fnp-3025	988	11	dementia	dementia	NOUN
fnp-3025	988	12	.	.	PUNCT
fnp-3025	989	1	brain	brain	NOUN
fnp-3025	989	2	,	,	PUNCT
fnp-3025	989	3	2009	2009	NUM
fnp-3025	989	4	.	.	PUNCT
fnp-3025	990	1	132(pt	132(pt	NUM
fnp-3025	990	2	4	4	NUM
fnp-3025	990	3	):	):	PUNCT
fnp-3025	990	4	p.	p.	NOUN
fnp-3025	990	5	1102	1102	NUM
fnp-3025	990	6	-	-	SYM
fnp-3025	990	7	11	11	NUM
fnp-3025	990	8	.	.	PUNCT
fnp-3025	990	9	88	88	NUM
fnp-3025	990	10	.	.	PUNCT
fnp-3025	991	1	redlich	redlich	PROPN
fnp-3025	991	2	,	,	PUNCT
fnp-3025	991	3	e.	e.	PROPN
fnp-3025	991	4	,	,	PUNCT
fnp-3025	991	5	ueber	ueber	PROPN
fnp-3025	991	6	miliare	miliare	NOUN
fnp-3025	991	7	sklerose	sklerose	ADJ
fnp-3025	991	8	der	der	ADJ
fnp-3025	991	9	hirnrinde	hirnrinde	NOUN
fnp-3025	991	10	bei	bei	NOUN
fnp-3025	991	11	seniler	seniler	NOUN
fnp-3025	991	12	atrophie	atrophie	NOUN
fnp-3025	991	13	.	.	PUNCT
fnp-3025	992	1	jahrbücher	jahrbücher	PROPN
fnp-3025	992	2	für	für	PROPN
fnp-3025	992	3	psychiatrie	psychiatrie	PROPN
fnp-3025	992	4	und	und	PROPN
fnp-3025	992	5	neurologie	neurologie	NOUN
fnp-3025	992	6	,	,	PUNCT
fnp-3025	992	7	1898	1898	NUM
fnp-3025	992	8	.	.	PUNCT
fnp-3025	993	1	17	17	NUM
fnp-3025	993	2	:	:	PUNCT
fnp-3025	994	1	p.	p.	NOUN
fnp-3025	994	2	208	208	NUM
fnp-3025	994	3	-	-	SYM
fnp-3025	994	4	216	216	NUM
fnp-3025	994	5	.	.	PUNCT
fnp-3025	994	6	89	89	NUM
fnp-3025	994	7	.	.	PUNCT
fnp-3025	995	1	ohry	ohry	PROPN
fnp-3025	995	2	,	,	PUNCT
fnp-3025	995	3	a.	a.	NOUN
fnp-3025	995	4	and	and	CCONJ
fnp-3025	995	5	o.	o.	PROPN
fnp-3025	995	6	buda	buda	PROPN
fnp-3025	995	7	,	,	PUNCT
fnp-3025	995	8	teofil	teofil	PROPN
fnp-3025	995	9	simchowicz	simchowicz	PROPN
fnp-3025	995	10	(	(	PUNCT
fnp-3025	995	11	1879	1879	NUM
fnp-3025	995	12	-	-	SYM
fnp-3025	995	13	1957	1957	NUM
fnp-3025	995	14	):	):	PUNCT
fnp-3025	995	15	the	the	DET
fnp-3025	995	16	scientist	scientist	NOUN
fnp-3025	995	17	who	who	PRON
fnp-3025	995	18	coined	coin	VERB
fnp-3025	995	19	senile	senile	ADJ
fnp-3025	995	20	plaques	plaque	NOUN
fnp-3025	995	21	in	in	ADP
fnp-3025	995	22	neuropathology	neuropathology	NOUN
fnp-3025	995	23	.	.	PUNCT
fnp-3025	996	1	rom	rom	PROPN
fnp-3025	997	1	j	j	PROPN
fnp-3025	997	2	morphol	morphol	NOUN
fnp-3025	997	3	embryol	embryol	NOUN
fnp-3025	997	4	,	,	PUNCT
fnp-3025	997	5	2015	2015	NUM
fnp-3025	997	6	.	.	PUNCT
fnp-3025	998	1	56(4	56(4	NUM
fnp-3025	998	2	):	):	PUNCT
fnp-3025	998	3	p.	p.	NOUN
fnp-3025	998	4	1545	1545	NUM
fnp-3025	998	5	-	-	SYM
fnp-3025	998	6	8	8	NUM
fnp-3025	998	7	.	.	X
fnp-3025	999	1	90	90	NUM
fnp-3025	999	2	.	.	X
fnp-3025	999	3	crook	crook	NOUN
fnp-3025	999	4	,	,	PUNCT
fnp-3025	999	5	r.	r.	PROPN
fnp-3025	999	6	,	,	PUNCT
fnp-3025	999	7	et	et	PROPN
fnp-3025	999	8	al	al	PROPN
fnp-3025	999	9	.	.	PROPN
fnp-3025	999	10	,	,	PUNCT
fnp-3025	999	11	a	a	DET
fnp-3025	999	12	variant	variant	NOUN
fnp-3025	999	13	of	of	ADP
fnp-3025	999	14	alzheimer	alzheimer	PROPN
fnp-3025	999	15	’s	’s	PART
fnp-3025	999	16	disease	disease	NOUN
fnp-3025	999	17	with	with	ADP
fnp-3025	999	18	spastic	spastic	ADJ
fnp-3025	999	19	paraparesis	paraparesis	NOUN
fnp-3025	999	20	and	and	CCONJ
fnp-3025	999	21	unusual	unusual	ADJ
fnp-3025	999	22	plaques	plaque	NOUN
fnp-3025	999	23	due	due	ADP
fnp-3025	999	24	to	to	ADP
fnp-3025	999	25	deletion	deletion	NOUN
fnp-3025	999	26	of	of	ADP
fnp-3025	999	27	exon	exon	NOUN
fnp-3025	999	28	9	9	NUM
fnp-3025	999	29	of	of	ADP
fnp-3025	999	30	presenilin	presenilin	PROPN
fnp-3025	999	31	1	1	NUM
fnp-3025	999	32	.	.	PUNCT
fnp-3025	1000	1	nat	nat	PROPN
fnp-3025	1000	2	med	med	PROPN
fnp-3025	1000	3	,	,	PUNCT
fnp-3025	1000	4	1998	1998	NUM
fnp-3025	1000	5	.	.	PUNCT
fnp-3025	1001	1	4(4	4(4	NUM
fnp-3025	1001	2	):	):	PUNCT
fnp-3025	1002	1	p.	p.	NOUN
fnp-3025	1002	2	452	452	NUM
fnp-3025	1002	3	-	-	SYM
fnp-3025	1002	4	5	5	NUM
fnp-3025	1002	5	.	.	NOUN
fnp-3025	1002	6	91	91	NUM
fnp-3025	1002	7	.	.	PUNCT
fnp-3025	1003	1	houlden	houlden	PROPN
fnp-3025	1003	2	,	,	PUNCT
fnp-3025	1003	3	h.	h.	PROPN
fnp-3025	1003	4	,	,	PUNCT
fnp-3025	1003	5	et	et	PROPN
fnp-3025	1003	6	al	al	PROPN
fnp-3025	1003	7	.	.	PROPN
fnp-3025	1003	8	,	,	PUNCT
fnp-3025	1003	9	variant	variant	PROPN
fnp-3025	1003	10	alzheimer	alzheimer	PROPN
fnp-3025	1003	11	’s	’s	PART
fnp-3025	1003	12	disease	disease	NOUN
fnp-3025	1003	13	with	with	ADP
fnp-3025	1003	14	spastic	spastic	ADJ
fnp-3025	1003	15	paraparesis	paraparesis	NOUN
fnp-3025	1003	16	and	and	CCONJ
fnp-3025	1003	17	cotton	cotton	NOUN
fnp-3025	1003	18	wool	wool	NOUN
fnp-3025	1003	19	plaques	plaque	NOUN
fnp-3025	1003	20	is	be	AUX
fnp-3025	1003	21	caused	cause	VERB
fnp-3025	1003	22	by	by	ADP
fnp-3025	1003	23	ps-1	ps-1	NOUN
fnp-3025	1003	24	mutations	mutation	NOUN
fnp-3025	1003	25	that	that	PRON
fnp-3025	1003	26	lead	lead	VERB
fnp-3025	1003	27	to	to	ADP
fnp-3025	1003	28	exceptionally	exceptionally	ADV
fnp-3025	1003	29	high	high	ADJ
fnp-3025	1003	30	amyloid	amyloid	NOUN
fnp-3025	1003	31	-	-	PUNCT
fnp-3025	1003	32	beta	beta	NOUN
fnp-3025	1003	33	concentrations	concentration	NOUN
fnp-3025	1003	34	.	.	PUNCT
fnp-3025	1004	1	ann	ann	PROPN
fnp-3025	1004	2	neurol	neurol	PROPN
fnp-3025	1004	3	,	,	PUNCT
fnp-3025	1004	4	2000	2000	NUM
fnp-3025	1004	5	.	.	PUNCT
fnp-3025	1005	1	48(5	48(5	PRON
fnp-3025	1005	2	):	):	PUNCT
fnp-3025	1005	3	p.	p.	NOUN
fnp-3025	1005	4	806	806	NUM
fnp-3025	1005	5	-	-	SYM
fnp-3025	1005	6	8	8	NUM
fnp-3025	1005	7	.	.	X
fnp-3025	1006	1	92	92	NUM
fnp-3025	1006	2	.	.	PUNCT
fnp-3025	1007	1	le	le	X
fnp-3025	1007	2	,	,	PUNCT
fnp-3025	1007	3	t.v	t.v	PROPN
fnp-3025	1007	4	.	.	PROPN
fnp-3025	1007	5	,	,	PUNCT
fnp-3025	1007	6	et	et	PROPN
fnp-3025	1007	7	al	al	PROPN
fnp-3025	1007	8	.	.	PROPN
fnp-3025	1007	9	,	,	PUNCT
fnp-3025	1007	10	cotton	cotton	NOUN
fnp-3025	1007	11	wool	wool	NOUN
fnp-3025	1007	12	plaques	plaque	NOUN
fnp-3025	1007	13	in	in	ADP
fnp-3025	1007	14	non	non	ADJ
fnp-3025	1007	15	-	-	ADJ
fnp-3025	1007	16	familial	familial	ADJ
fnp-3025	1007	17	late	late	ADJ
fnp-3025	1007	18	-	-	PUNCT
fnp-3025	1007	19	onset	onset	NOUN
fnp-3025	1007	20	alzheimer	alzheimer	NOUN
fnp-3025	1007	21	disease	disease	NOUN
fnp-3025	1007	22	.	.	PUNCT
fnp-3025	1008	1	j	j	PROPN
fnp-3025	1008	2	neuropathol	neuropathol	PROPN
fnp-3025	1008	3	exp	exp	PROPN
fnp-3025	1008	4	neurol	neurol	PROPN
fnp-3025	1008	5	,	,	PUNCT
fnp-3025	1008	6	2001	2001	NUM
fnp-3025	1008	7	.	.	PUNCT
fnp-3025	1009	1	60(11	60(11	NUM
fnp-3025	1009	2	):	):	PUNCT
fnp-3025	1009	3	p.	p.	NOUN
fnp-3025	1009	4	1051	1051	NUM
fnp-3025	1009	5	-	-	SYM
fnp-3025	1009	6	61	61	NUM
fnp-3025	1009	7	.	.	PUNCT
fnp-3025	1010	1	93	93	NUM
fnp-3025	1010	2	.	.	PUNCT
fnp-3025	1011	1	miki	miki	PROPN
fnp-3025	1011	2	,	,	PUNCT
fnp-3025	1011	3	t.	t.	PROPN
fnp-3025	1011	4	,	,	PUNCT
fnp-3025	1011	5	et	et	PROPN
fnp-3025	1011	6	al	al	PROPN
fnp-3025	1011	7	.	.	PROPN
fnp-3025	1011	8	,	,	PUNCT
fnp-3025	1011	9	young	young	ADJ
fnp-3025	1011	10	adult	adult	NOUN
fnp-3025	1011	11	-	-	PUNCT
fnp-3025	1011	12	onset	onset	NOUN
fnp-3025	1011	13	,	,	PUNCT
fnp-3025	1011	14	very	very	ADV
fnp-3025	1011	15	slowly	slowly	ADV
fnp-3025	1011	16	progressive	progressive	ADJ
fnp-3025	1011	17	cognitive	cognitive	ADJ
fnp-3025	1011	18	decline	decline	NOUN
fnp-3025	1011	19	with	with	ADP
fnp-3025	1011	20	spastic	spastic	ADJ
fnp-3025	1011	21	paraparesis	paraparesis	NOUN
fnp-3025	1011	22	in	in	ADP
fnp-3025	1011	23	alzheimer	alzheimer	PROPN
fnp-3025	1011	24	’s	’s	PART
fnp-3025	1011	25	disease	disease	NOUN
fnp-3025	1011	26	with	with	ADP
fnp-3025	1011	27	cotton	cotton	NOUN
fnp-3025	1011	28	wool	wool	NOUN
fnp-3025	1011	29	plaques	plaque	NOUN
fnp-3025	1011	30	due	due	ADJ
fnp-3025	1011	31	to	to	ADP
fnp-3025	1011	32	a	a	DET
fnp-3025	1011	33	novel	novel	ADJ
fnp-3025	1011	34	presenilin1	presenilin1	NOUN
fnp-3025	1011	35	g417s	g417s	PROPN
fnp-3025	1011	36	mutation	mutation	NOUN
fnp-3025	1011	37	.	.	PUNCT
fnp-3025	1012	1	acta	acta	PROPN
fnp-3025	1012	2	neuropathol	neuropathol	PROPN
fnp-3025	1012	3	commun	commun	PROPN
fnp-3025	1012	4	,	,	PUNCT
fnp-3025	1012	5	2019	2019	NUM
fnp-3025	1012	6	.	.	PUNCT
fnp-3025	1013	1	7(1	7(1	NUM
fnp-3025	1013	2	):	):	PUNCT
fnp-3025	1013	3	p.	p.	NOUN
fnp-3025	1013	4	19	19	NUM
fnp-3025	1013	5	.	.	PUNCT
fnp-3025	1014	1	94	94	NUM
fnp-3025	1014	2	.	.	PUNCT
fnp-3025	1015	1	miravalle	miravalle	PROPN
fnp-3025	1015	2	,	,	PUNCT
fnp-3025	1015	3	l.	l.	PROPN
fnp-3025	1015	4	,	,	PUNCT
fnp-3025	1015	5	et	et	PROPN
fnp-3025	1015	6	al	al	PROPN
fnp-3025	1015	7	.	.	PROPN
fnp-3025	1015	8	,	,	PUNCT
fnp-3025	1015	9	amino	amino	NOUN
fnp-3025	1015	10	-	-	PUNCT
fnp-3025	1015	11	terminally	terminally	ADV
fnp-3025	1015	12	truncated	truncated	ADJ
fnp-3025	1015	13	abeta	abeta	PROPN
fnp-3025	1015	14	peptide	peptide	NOUN
fnp-3025	1015	15	species	specie	NOUN
fnp-3025	1015	16	are	be	AUX
fnp-3025	1015	17	the	the	DET
fnp-3025	1015	18	main	main	ADJ
fnp-3025	1015	19	component	component	NOUN
fnp-3025	1015	20	of	of	ADP
fnp-3025	1015	21	cotton	cotton	NOUN
fnp-3025	1015	22	wool	wool	NOUN
fnp-3025	1015	23	plaques	plaque	NOUN
fnp-3025	1015	24	.	.	PUNCT
fnp-3025	1016	1	biochemistry	biochemistry	NOUN
fnp-3025	1016	2	,	,	PUNCT
fnp-3025	1016	3	2005	2005	NUM
fnp-3025	1016	4	.	.	PUNCT
fnp-3025	1017	1	44(32	44(32	NUM
fnp-3025	1017	2	):	):	PUNCT
fnp-3025	1017	3	p.	p.	NOUN
fnp-3025	1017	4	10810	10810	NUM
fnp-3025	1017	5	-	-	SYM
fnp-3025	1017	6	21	21	NUM
fnp-3025	1017	7	.	.	PUNCT
fnp-3025	1018	1	95	95	NUM
fnp-3025	1018	2	.	.	PUNCT
fnp-3025	1019	1	alzheimer	alzheimer	PROPN
fnp-3025	1019	2	,	,	PUNCT
fnp-3025	1019	3	a.	a.	PROPN
fnp-3025	1019	4	,	,	PUNCT
fnp-3025	1019	5	über	über	PROPN
fnp-3025	1019	6	eine	eine	PROPN
fnp-3025	1019	7	eigenartige	eigenartige	PROPN
fnp-3025	1019	8	erkrankung	erkrankung	PROPN
fnp-3025	1019	9	der	der	ADJ
fnp-3025	1019	10	hirnrinde	hirnrinde	NOUN
fnp-3025	1019	11	.	.	PUNCT
fnp-3025	1020	1	allgemeine	allgemeine	PROPN
fnp-3025	1020	2	zeitschrift	zeitschrift	PROPN
fnp-3025	1020	3	für	für	PROPN
fnp-3025	1020	4	psychiatrie	psychiatrie	PROPN
fnp-3025	1020	5	,	,	PUNCT
fnp-3025	1020	6	1907	1907	NUM
fnp-3025	1020	7	.	.	PUNCT
fnp-3025	1021	1	64	64	NUM
fnp-3025	1021	2	:	:	PUNCT
fnp-3025	1022	1	p.	p.	NOUN
fnp-3025	1022	2	146	146	NUM
fnp-3025	1022	3	-	-	SYM
fnp-3025	1022	4	148	148	NUM
fnp-3025	1022	5	.	.	PUNCT
fnp-3025	1023	1	96	96	NUM
fnp-3025	1023	2	.	.	PUNCT
fnp-3025	1023	3	alzheimer	alzheimer	PROPN
fnp-3025	1023	4	,	,	PUNCT
fnp-3025	1023	5	a.	a.	PROPN
fnp-3025	1023	6	,	,	PUNCT
fnp-3025	1023	7	über	über	PROPN
fnp-3025	1023	8	eigenartige	eigenartige	PROPN
fnp-3025	1023	9	krankheitsfälle	krankheitsfälle	PROPN
fnp-3025	1023	10	des	des	PROPN
fnp-3025	1023	11	späteren	späteren	PROPN
fnp-3025	1023	12	alters	alter	VERB
fnp-3025	1023	13	.	.	PUNCT
fnp-3025	1024	1	zeitschrift	zeitschrift	PROPN
fnp-3025	1024	2	für	für	PROPN
fnp-3025	1024	3	die	die	VERB
fnp-3025	1024	4	gesamte	gesamte	PROPN
fnp-3025	1024	5	neurologie	neurologie	X
fnp-3025	1024	6	und	und	VERB
fnp-3025	1024	7	psychiatrie	psychiatrie	NOUN
fnp-3025	1024	8	,	,	PUNCT
fnp-3025	1024	9	1911	1911	NUM
fnp-3025	1024	10	.	.	PUNCT
fnp-3025	1025	1	4	4	NUM
fnp-3025	1025	2	:	:	PUNCT
fnp-3025	1025	3	p.	p.	NOUN
fnp-3025	1025	4	356	356	NUM
fnp-3025	1025	5	-	-	SYM
fnp-3025	1025	6	385	385	NUM
fnp-3025	1025	7	.	.	PUNCT
fnp-3025	1026	1	97	97	NUM
fnp-3025	1026	2	.	.	PUNCT
fnp-3025	1027	1	miyake	miyake	PROPN
fnp-3025	1027	2	,	,	PUNCT
fnp-3025	1027	3	k.	k.	PROPN
fnp-3025	1027	4	,	,	PUNCT
fnp-3025	1027	5	beiträge	beiträge	PROPN
fnp-3025	1027	6	zur	zur	NOUN
fnp-3025	1027	7	kenntnis	kenntnis	NOUN
fnp-3025	1027	8	der	der	ADJ
fnp-3025	1027	9	altersveränderungen	altersveränderungen	PROPN
fnp-3025	1027	10	der	der	NOUN
fnp-3025	1027	11	menschilchen	menschilchen	PROPN
fnp-3025	1027	12	hirnrinde	hirnrinde	PROPN
fnp-3025	1027	13	.	.	PUNCT
fnp-3025	1028	1	arbeiten	arbeiten	VERB
fnp-3025	1028	2	obersteinerschen	obersteinerschen	PROPN
fnp-3025	1028	3	neurologische	neurologische	PROPN
fnp-3025	1028	4	institut	institut	PROPN
fnp-3025	1028	5	wien	wien	PROPN
fnp-3025	1028	6	,	,	PUNCT
fnp-3025	1028	7	1906	1906	NUM
fnp-3025	1028	8	.	.	PUNCT
fnp-3025	1029	1	13	13	NUM
fnp-3025	1029	2	:	:	PUNCT
fnp-3025	1029	3	p.	p.	NOUN
fnp-3025	1029	4	212	212	NUM
fnp-3025	1029	5	-	-	SYM
fnp-3025	1029	6	259	259	NUM
fnp-3025	1029	7	.	.	NOUN
fnp-3025	1029	8	98	98	NUM
fnp-3025	1029	9	.	.	PUNCT
fnp-3025	1030	1	lafora	lafora	PROPN
fnp-3025	1030	2	,	,	PUNCT
fnp-3025	1030	3	g.r	g.r	PROPN
fnp-3025	1030	4	.	.	PROPN
fnp-3025	1030	5	,	,	PUNCT
fnp-3025	1031	1	beitrag	beitrag	PROPN
fnp-3025	1031	2	zur	zur	PROPN
fnp-3025	1031	3	kenntnis	kenntnis	PROPN
fnp-3025	1031	4	der	der	PROPN
fnp-3025	1031	5	alzheimerschen	alzheimerschen	ADV
fnp-3025	1031	6	krankheit	krankheit	PROPN
fnp-3025	1031	7	oder	oder	VERB
fnp-3025	1031	8	präsenilen	präsenilen	VERB
fnp-3025	1031	9	demenz	demenz	ADP
fnp-3025	1031	10	mit	mit	NOUN
fnp-3025	1031	11	herdsymptomen	herdsymptoman	NOUN
fnp-3025	1031	12	.	.	PUNCT
fnp-3025	1032	1	zeitschrift	zeitschrift	PROPN
fnp-3025	1032	2	für	für	PROPN
fnp-3025	1032	3	die	die	VERB
fnp-3025	1032	4	gesamte	gesamte	PROPN
fnp-3025	1032	5	neurologie	neurologie	X
fnp-3025	1032	6	und	und	VERB
fnp-3025	1032	7	psychiatrie	psychiatrie	NOUN
fnp-3025	1032	8	,	,	PUNCT
fnp-3025	1032	9	1911	1911	NUM
fnp-3025	1032	10	.	.	PUNCT
fnp-3025	1033	1	6(1	6(1	NUM
fnp-3025	1033	2	):	):	PUNCT
fnp-3025	1034	1	p.	p.	NOUN
fnp-3025	1034	2	15	15	NUM
fnp-3025	1034	3	.	.	PUNCT
fnp-3025	1034	4	99	99	NUM
fnp-3025	1034	5	.	.	PUNCT
fnp-3025	1035	1	bonfiglio	bonfiglio	PROPN
fnp-3025	1035	2	,	,	PUNCT
fnp-3025	1035	3	f.	f.	PROPN
fnp-3025	1035	4	,	,	PUNCT
fnp-3025	1035	5	di	di	PROPN
fnp-3025	1035	6	speciali	speciali	PROPN
fnp-3025	1035	7	reperti	reperti	PROPN
fnp-3025	1035	8	in	in	ADP
fnp-3025	1035	9	un	un	PROPN
fnp-3025	1035	10	caso	caso	PROPN
fnp-3025	1035	11	di	di	X
fnp-3025	1035	12	probabile	probabile	NOUN
fnp-3025	1035	13	sifilide	sifilide	PROPN
fnp-3025	1035	14	cerebrale	cerebrale	NOUN
fnp-3025	1035	15	.	.	PUNCT
fnp-3025	1036	1	rivista	rivista	NOUN
fnp-3025	1036	2	sperimentale	sperimentale	PROPN
fnp-3025	1036	3	di	di	PROPN
fnp-3025	1036	4	feniatria	feniatria	PROPN
fnp-3025	1036	5	1908	1908	NUM
fnp-3025	1036	6	.	.	PUNCT
fnp-3025	1037	1	34	34	NUM
fnp-3025	1037	2	:	:	PUNCT
fnp-3025	1038	1	p.	p.	NOUN
fnp-3025	1038	2	196	196	NUM
fnp-3025	1038	3	-	-	SYM
fnp-3025	1038	4	206	206	NUM
fnp-3025	1038	5	.	.	PUNCT
fnp-3025	1038	6	100	100	NUM
fnp-3025	1038	7	.	.	PUNCT
fnp-3025	1039	1	hübner	hübner	NOUN
fnp-3025	1039	2	,	,	PUNCT
fnp-3025	1039	3	a.h	a.h	PROPN
fnp-3025	1039	4	.	.	PROPN
fnp-3025	1039	5	,	,	PUNCT
fnp-3025	1039	6	zur	zur	NOUN
fnp-3025	1039	7	histopathologie	histopathologie	X
fnp-3025	1039	8	der	der	ADJ
fnp-3025	1039	9	senilen	senilen	ADJ
fnp-3025	1039	10	hirnrinde	hirnrinde	NOUN
fnp-3025	1039	11	.	.	PUNCT
fnp-3025	1040	1	archiv	archiv	PROPN
fnp-3025	1040	2	für	für	PROPN
fnp-3025	1040	3	psychiatrie	psychiatrie	PROPN
fnp-3025	1040	4	und	und	PROPN
fnp-3025	1040	5	nervenkrankheiten	nervenkrankheiten	VERB
fnp-3025	1040	6	,	,	PUNCT
fnp-3025	1040	7	1909	1909	NUM
fnp-3025	1040	8	.	.	PUNCT
fnp-3025	1041	1	46(2	46(2	NUM
fnp-3025	1041	2	):	):	PUNCT
fnp-3025	1042	1	p.	p.	NOUN
fnp-3025	1042	2	598	598	NUM
fnp-3025	1042	3	-	-	SYM
fnp-3025	1042	4	609	609	NUM
fnp-3025	1042	5	.	.	PUNCT
fnp-3025	1043	1	101	101	NUM
fnp-3025	1043	2	.	.	PUNCT
fnp-3025	1043	3	perusini	perusini	PROPN
fnp-3025	1043	4	,	,	PUNCT
fnp-3025	1043	5	g.	g.	PROPN
fnp-3025	1043	6	,	,	PUNCT
fnp-3025	1043	7	über	über	PROPN
fnp-3025	1043	8	klinisch	klinisch	PROPN
fnp-3025	1043	9	und	und	VERB
fnp-3025	1043	10	histologisch	histologisch	PROPN
fnp-3025	1043	11	eigenartige	eigenartige	PROPN
fnp-3025	1043	12	psychische	psychische	PROPN
fnp-3025	1043	13	erkrankungen	erkrankungen	PROPN
fnp-3025	1043	14	des	des	PROPN
fnp-3025	1043	15	höheren	höheren	PROPN
fnp-3025	1043	16	lebensalters	lebensalters	PROPN
fnp-3025	1043	17	,	,	PUNCT
fnp-3025	1043	18	in	in	ADP
fnp-3025	1043	19	histologische	histologische	PROPN
fnp-3025	1043	20	und	und	PROPN
fnp-3025	1043	21	histopathologische	histopathologische	PROPN
fnp-3025	1043	22	arbeiten	arbeiten	PROPN
fnp-3025	1043	23	über	über	PROPN
fnp-3025	1043	24	die	die	NOUN
fnp-3025	1043	25	grosshirnrinde	grosshirnrinde	NOUN
fnp-3025	1043	26	,	,	PUNCT
fnp-3025	1043	27	f.	f.	PROPN
fnp-3025	1043	28	nissl	nissl	PROPN
fnp-3025	1043	29	and	and	CCONJ
fnp-3025	1043	30	a.	a.	PROPN
fnp-3025	1043	31	alzheimer	alzheimer	PROPN
fnp-3025	1043	32	,	,	PUNCT
fnp-3025	1043	33	editors	editor	NOUN
fnp-3025	1043	34	.	.	PUNCT
fnp-3025	1044	1	1910	1910	NUM
fnp-3025	1044	2	,	,	PUNCT
fnp-3025	1044	3	fischer	fischer	PROPN
fnp-3025	1044	4	-	-	PUNCT
fnp-3025	1044	5	verlag	verlag	PROPN
fnp-3025	1044	6	:	:	PUNCT
fnp-3025	1044	7	jena	jena	PROPN
fnp-3025	1044	8	.	.	PUNCT
fnp-3025	1045	1	p.	p.	NOUN
fnp-3025	1045	2	297	297	NUM
fnp-3025	1045	3	-	-	SYM
fnp-3025	1045	4	351	351	NUM
fnp-3025	1045	5	.	.	PUNCT
fnp-3025	1045	6	102	102	NUM
fnp-3025	1045	7	.	.	PUNCT
fnp-3025	1046	1	fuller	full	ADJ
fnp-3025	1046	2	,	,	PUNCT
fnp-3025	1046	3	s.c	s.c	PROPN
fnp-3025	1046	4	.	.	PROPN
fnp-3025	1046	5	,	,	PUNCT
fnp-3025	1046	6	a	a	DET
fnp-3025	1046	7	study	study	NOUN
fnp-3025	1046	8	of	of	ADP
fnp-3025	1046	9	the	the	DET
fnp-3025	1046	10	miliary	miliary	ADJ
fnp-3025	1046	11	plaques	plaque	NOUN
fnp-3025	1046	12	found	find	VERB
fnp-3025	1046	13	in	in	ADP
fnp-3025	1046	14	brains	brain	NOUN
fnp-3025	1046	15	of	of	ADP
fnp-3025	1046	16	the	the	DET
fnp-3025	1046	17	aged	age	VERB
fnp-3025	1046	18	.	.	PUNCT
fnp-3025	1047	1	american	american	PROPN
fnp-3025	1047	2	journal	journal	PROPN
fnp-3025	1047	3	of	of	ADP
fnp-3025	1047	4	insanity	insanity	NOUN
fnp-3025	1047	5	,	,	PUNCT
fnp-3025	1047	6	1911	1911	NUM
fnp-3025	1047	7	.	.	PUNCT
fnp-3025	1048	1	68(2	68(2	NOUN
fnp-3025	1048	2	):	):	PUNCT
fnp-3025	1048	3	p.	p.	NOUN
fnp-3025	1048	4	147	147	NUM
fnp-3025	1048	5	-	-	SYM
fnp-3025	1048	6	219	219	NUM
fnp-3025	1048	7	.	.	PUNCT
fnp-3025	1049	1	103	103	NUM
fnp-3025	1049	2	.	.	PUNCT
fnp-3025	1050	1	bielschowsky	bielschowsky	NOUN
fnp-3025	1050	2	,	,	PUNCT
fnp-3025	1050	3	m.	m.	NOUN
fnp-3025	1050	4	,	,	PUNCT
fnp-3025	1050	5	zur	zur	NOUN
fnp-3025	1050	6	kenntnis	kenntnis	NOUN
fnp-3025	1050	7	der	der	NOUN
fnp-3025	1050	8	alzheimerschen	alzheimerschen	PROPN
fnp-3025	1050	9	krankheit	krankheit	PROPN
fnp-3025	1050	10	(	(	PUNCT
fnp-3025	1050	11	präsenilen	präsenilen	VERB
fnp-3025	1050	12	demenz	demenz	ADP
fnp-3025	1050	13	mit	mit	NOUN
fnp-3025	1050	14	herdsymptomen	herdsymptoman	NOUN
fnp-3025	1050	15	)	)	PUNCT
fnp-3025	1050	16	.	.	PUNCT
fnp-3025	1051	1	journal	journal	PROPN
fnp-3025	1051	2	für	für	PROPN
fnp-3025	1051	3	psychologie	psychologie	PROPN
fnp-3025	1051	4	und	und	PROPN
fnp-3025	1051	5	neurologie	neurologie	PROPN
fnp-3025	1051	6	1911	1911	NUM
fnp-3025	1051	7	.	.	PUNCT
fnp-3025	1052	1	18	18	NUM
fnp-3025	1052	2	:	:	PUNCT
fnp-3025	1052	3	p.	p.	NOUN
fnp-3025	1052	4	1	1	NUM
fnp-3025	1052	5	-	-	SYM
fnp-3025	1052	6	20	20	NUM
fnp-3025	1052	7	.	.	PUNCT
fnp-3025	1052	8	104	104	NUM
fnp-3025	1052	9	.	.	PUNCT
fnp-3025	1053	1	barrett	barrett	PROPN
fnp-3025	1053	2	,	,	PUNCT
fnp-3025	1053	3	a.m.	a.m.	ADV
fnp-3025	1053	4	,	,	PUNCT
fnp-3025	1053	5	degeneration	degeneration	NOUN
fnp-3025	1053	6	of	of	ADP
fnp-3025	1053	7	intracellular	intracellular	ADJ
fnp-3025	1053	8	neurofibrils	neurofibril	NOUN
fnp-3025	1053	9	with	with	ADP
fnp-3025	1053	10	miliary	miliary	ADJ
fnp-3025	1053	11	gliosis	gliosis	NOUN
fnp-3025	1053	12	in	in	ADP
fnp-3025	1053	13	psychoses	psychosis	NOUN
fnp-3025	1053	14	of	of	ADP
fnp-3025	1053	15	the	the	DET
fnp-3025	1053	16	senile	senile	ADJ
fnp-3025	1053	17	period	period	NOUN
fnp-3025	1053	18	.	.	PUNCT
fnp-3025	1054	1	american	american	ADJ
fnp-3025	1054	2	journal	journal	PROPN
fnp-3025	1054	3	of	of	ADP
fnp-3025	1054	4	insanity	insanity	NOUN
fnp-3025	1054	5	,	,	PUNCT
fnp-3025	1054	6	1911	1911	NUM
fnp-3025	1054	7	.	.	PUNCT
fnp-3025	1055	1	67(3	67(3	NUM
fnp-3025	1055	2	):	):	PUNCT
fnp-3025	1056	1	p.	p.	NOUN
fnp-3025	1056	2	503	503	NUM
fnp-3025	1056	3	-	-	SYM
fnp-3025	1056	4	516	516	NUM
fnp-3025	1056	5	.	.	PUNCT
fnp-3025	1056	6	105	105	NUM
fnp-3025	1056	7	.	.	PUNCT
fnp-3025	1057	1	simchowicz	simchowicz	ADJ
fnp-3025	1057	2	,	,	PUNCT
fnp-3025	1057	3	t.	t.	PROPN
fnp-3025	1057	4	,	,	PUNCT
fnp-3025	1057	5	histologische	histologische	PROPN
fnp-3025	1057	6	studien	studien	PROPN
fnp-3025	1057	7	über	über	PROPN
fnp-3025	1057	8	die	die	VERB
fnp-3025	1057	9	senile	senile	ADJ
fnp-3025	1057	10	demenz	demenz	PROPN
fnp-3025	1057	11	,	,	PUNCT
fnp-3025	1057	12	in	in	ADP
fnp-3025	1057	13	histologische	histologische	PROPN
fnp-3025	1057	14	und	und	PROPN
fnp-3025	1057	15	histopathologische	histopathologische	PROPN
fnp-3025	1057	16	arbeiten	arbeiten	PROPN
fnp-3025	1057	17	über	über	PROPN
fnp-3025	1057	18	die	die	NOUN
fnp-3025	1057	19	grosshirnrinde	grosshirnrinde	NOUN
fnp-3025	1057	20	,	,	PUNCT
fnp-3025	1057	21	f.	f.	PROPN
fnp-3025	1057	22	nissl	nissl	PROPN
fnp-3025	1057	23	and	and	CCONJ
fnp-3025	1057	24	a.	a.	PROPN
fnp-3025	1057	25	alzheimer	alzheimer	PROPN
fnp-3025	1057	26	,	,	PUNCT
fnp-3025	1057	27	editors	editor	NOUN
fnp-3025	1057	28	.	.	PUNCT
fnp-3025	1058	1	1911	1911	NUM
fnp-3025	1058	2	,	,	PUNCT
fnp-3025	1058	3	fischer	fischer	PROPN
fnp-3025	1058	4	-	-	PUNCT
fnp-3025	1058	5	verlag	verlag	PROPN
fnp-3025	1058	6	:	:	PUNCT
fnp-3025	1058	7	jena	jena	PROPN
fnp-3025	1058	8	.	.	PUNCT
fnp-3025	1059	1	p.	p.	NOUN
fnp-3025	1059	2	267	267	NUM
fnp-3025	1059	3	-	-	SYM
fnp-3025	1059	4	444	444	NUM
fnp-3025	1059	5	.	.	NOUN
fnp-3025	1059	6	106	106	NUM
fnp-3025	1059	7	.	.	PUNCT
fnp-3025	1060	1	marinesco	marinesco	PROPN
fnp-3025	1060	2	,	,	PUNCT
fnp-3025	1060	3	g.	g.	PROPN
fnp-3025	1060	4	and	and	CCONJ
fnp-3025	1060	5	j.	j.	PROPN
fnp-3025	1060	6	minea	minea	PROPN
fnp-3025	1060	7	,	,	PUNCT
fnp-3025	1060	8	untersuchungen	untersuchungen	PROPN
fnp-3025	1060	9	über	über	PROPN
fnp-3025	1060	10	die	die	VERB
fnp-3025	1060	11	“	"	PUNCT
fnp-3025	1060	12	senilen	senilen	ADJ
fnp-3025	1060	13	plaques	plaque	NOUN
fnp-3025	1060	14	”	"	PUNCT
fnp-3025	1060	15	.	.	PUNCT
fnp-3025	1061	1	monatschrift	monatschrift	PROPN
fnp-3025	1061	2	für	für	PROPN
fnp-3025	1061	3	psychiatrie	psychiatrie	PROPN
fnp-3025	1061	4	und	und	PROPN
fnp-3025	1061	5	neurologie	neurologie	NOUN
fnp-3025	1061	6	,	,	PUNCT
fnp-3025	1061	7	1912	1912	NUM
fnp-3025	1061	8	.	.	PUNCT
fnp-3025	1062	1	31	31	NUM
fnp-3025	1062	2	:	:	PUNCT
fnp-3025	1062	3	p.	p.	NOUN
fnp-3025	1062	4	79	79	NUM
fnp-3025	1062	5	-	-	SYM
fnp-3025	1062	6	91	91	NUM
fnp-3025	1062	7	.	.	PUNCT
fnp-3025	1062	8	107	107	NUM
fnp-3025	1062	9	.	.	PUNCT
fnp-3025	1063	1	christen	christen	VERB
fnp-3025	1063	2	,	,	PUNCT
fnp-3025	1063	3	y.	y.	PROPN
fnp-3025	1063	4	,	,	PUNCT
fnp-3025	1063	5	alois	alois	PROPN
fnp-3025	1063	6	alzheimer	alzheimer	PROPN
fnp-3025	1063	7	and	and	CCONJ
fnp-3025	1063	8	the	the	DET
fnp-3025	1063	9	myth	myth	NOUN
fnp-3025	1063	10	of	of	ADP
fnp-3025	1063	11	the	the	DET
fnp-3025	1063	12	pioneer	pioneer	NOUN
fnp-3025	1063	13	,	,	PUNCT
fnp-3025	1063	14	in	in	ADP
fnp-3025	1063	15	alzheimer	alzheimer	PROPN
fnp-3025	1063	16	:	:	PUNCT
fnp-3025	1063	17	100	100	NUM
fnp-3025	1063	18	years	year	NOUN
fnp-3025	1063	19	and	and	CCONJ
fnp-3025	1063	20	beyond	beyond	ADP
fnp-3025	1063	21	,	,	PUNCT
fnp-3025	1063	22	m.	m.	NOUN
fnp-3025	1063	23	jucker	jucker	NOUN
fnp-3025	1063	24	,	,	PUNCT
fnp-3025	1063	25	et	et	PROPN
fnp-3025	1063	26	al	al	PROPN
fnp-3025	1063	27	.	.	PROPN
fnp-3025	1063	28	,	,	PUNCT
fnp-3025	1063	29	editors	editor	NOUN
fnp-3025	1063	30	.	.	PUNCT
fnp-3025	1064	1	2006	2006	NUM
fnp-3025	1064	2	,	,	PUNCT
fnp-3025	1064	3	springer	springer	NOUN
fnp-3025	1064	4	:	:	PUNCT
fnp-3025	1064	5	berlin	berlin	PROPN
fnp-3025	1064	6	heidelberg	heidelberg	PROPN
fnp-3025	1064	7	new	new	PROPN
fnp-3025	1064	8	york	york	PROPN
fnp-3025	1064	9	.	.	PUNCT
fnp-3025	1065	1	p.	p.	NOUN
fnp-3025	1065	2	51	51	NUM
fnp-3025	1066	1	-	-	SYM
fnp-3025	1066	2	55	55	NUM
fnp-3025	1066	3	.	.	PUNCT
fnp-3025	1067	1	108	108	NUM
fnp-3025	1067	2	.	.	PUNCT
fnp-3025	1068	1	braak	braak	PROPN
fnp-3025	1068	2	,	,	PUNCT
fnp-3025	1068	3	h.	h.	PROPN
fnp-3025	1068	4	and	and	CCONJ
fnp-3025	1068	5	e.	e.	PROPN
fnp-3025	1068	6	braak	braak	PROPN
fnp-3025	1068	7	,	,	PUNCT
fnp-3025	1068	8	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1068	9	changes	change	NOUN
fnp-3025	1068	10	:	:	PUNCT
fnp-3025	1068	11	the	the	DET
fnp-3025	1068	12	hallmark	hallmark	NOUN
fnp-3025	1068	13	of	of	ADP
fnp-3025	1068	14	alzheimer	alzheimer	PROPN
fnp-3025	1068	15	disease	disease	PROPN
fnp-3025	1068	16	,	,	PUNCT
fnp-3025	1068	17	in	in	ADP
fnp-3025	1068	18	concepts	concept	NOUN
fnp-3025	1068	19	of	of	ADP
fnp-3025	1068	20	alzheimer	alzheimer	PROPN
fnp-3025	1068	21	disease	disease	PROPN
fnp-3025	1068	22	:	:	PUNCT
fnp-3025	1068	23	biological	biological	ADJ
fnp-3025	1068	24	,	,	PUNCT
fnp-3025	1068	25	clinical	clinical	ADJ
fnp-3025	1068	26	and	and	CCONJ
fnp-3025	1068	27	cultural	cultural	ADJ
fnp-3025	1068	28	perspectives	perspective	NOUN
fnp-3025	1068	29	,	,	PUNCT
fnp-3025	1068	30	p.j	p.j	PROPN
fnp-3025	1068	31	.	.	PROPN
fnp-3025	1068	32	whitehouse	whitehouse	PROPN
fnp-3025	1068	33	,	,	PUNCT
fnp-3025	1068	34	k.	k.	PROPN
fnp-3025	1068	35	mauer	mauer	PROPN
fnp-3025	1068	36	,	,	PUNCT
fnp-3025	1068	37	and	and	CCONJ
fnp-3025	1068	38	j.	j.	PROPN
fnp-3025	1068	39	ballenger	ballenger	PROPN
fnp-3025	1068	40	,	,	PUNCT
fnp-3025	1068	41	editors	editor	NOUN
fnp-3025	1068	42	.	.	PUNCT
fnp-3025	1069	1	2000	2000	NUM
fnp-3025	1069	2	,	,	PUNCT
fnp-3025	1069	3	johns	johns	PROPN
fnp-3025	1069	4	hopkins	hopkins	PROPN
fnp-3025	1069	5	university	university	PROPN
fnp-3025	1069	6	press	press	NOUN
fnp-3025	1069	7	:	:	PUNCT
fnp-3025	1069	8	baltimore	baltimore	PROPN
fnp-3025	1069	9	.	.	PUNCT
fnp-3025	1070	1	p.	p.	NOUN
fnp-3025	1070	2	53	53	NUM
fnp-3025	1071	1	-	-	SYM
fnp-3025	1071	2	71	71	NUM
fnp-3025	1071	3	.	.	PUNCT
fnp-3025	1072	1	109	109	NUM
fnp-3025	1072	2	.	.	PUNCT
fnp-3025	1073	1	jack	jack	PROPN
fnp-3025	1073	2	,	,	PUNCT
fnp-3025	1073	3	c.r	c.r	PROPN
fnp-3025	1073	4	.	.	PROPN
fnp-3025	1073	5	,	,	PUNCT
fnp-3025	1073	6	jr	jr	PROPN
fnp-3025	1073	7	.	.	PROPN
fnp-3025	1073	8	,	,	PUNCT
fnp-3025	1073	9	et	et	PROPN
fnp-3025	1073	10	al	al	PROPN
fnp-3025	1073	11	.	.	PROPN
fnp-3025	1073	12	,	,	PUNCT
fnp-3025	1073	13	nia	nia	PROPN
fnp-3025	1073	14	-	-	PUNCT
fnp-3025	1073	15	aa	aa	PROPN
fnp-3025	1073	16	research	research	NOUN
fnp-3025	1073	17	framework	framework	NOUN
fnp-3025	1073	18	:	:	PUNCT
fnp-3025	1073	19	toward	toward	ADP
fnp-3025	1073	20	a	a	DET
fnp-3025	1073	21	biological	biological	ADJ
fnp-3025	1073	22	definition	definition	NOUN
fnp-3025	1073	23	of	of	ADP
fnp-3025	1073	24	alzheimer	alzheimer	PROPN
fnp-3025	1073	25	’s	’s	PART
fnp-3025	1073	26	disease	disease	NOUN
fnp-3025	1073	27	.	.	PUNCT
fnp-3025	1074	1	alzheimers	alzheimers	PROPN
fnp-3025	1074	2	dement	dement	PROPN
fnp-3025	1074	3	,	,	PUNCT
fnp-3025	1074	4	2018	2018	NUM
fnp-3025	1074	5	.	.	PUNCT
fnp-3025	1075	1	14(4	14(4	NOUN
fnp-3025	1075	2	):	):	PUNCT
fnp-3025	1075	3	p.	p.	NOUN
fnp-3025	1075	4	535	535	NUM
fnp-3025	1075	5	-	-	SYM
fnp-3025	1075	6	562	562	NUM
fnp-3025	1075	7	.	.	PUNCT
fnp-3025	1076	1	110	110	NUM
fnp-3025	1076	2	.	.	X
fnp-3025	1077	1	bick	bick	PROPN
fnp-3025	1077	2	,	,	PUNCT
fnp-3025	1077	3	k.	k.	PROPN
fnp-3025	1077	4	,	,	PUNCT
fnp-3025	1077	5	l.	l.	PROPN
fnp-3025	1077	6	amaducci	amaducci	PROPN
fnp-3025	1077	7	,	,	PUNCT
fnp-3025	1077	8	and	and	CCONJ
fnp-3025	1077	9	g.	g.	PROPN
fnp-3025	1077	10	pepeu	pepeu	PROPN
fnp-3025	1077	11	,	,	PUNCT
fnp-3025	1077	12	the	the	DET
fnp-3025	1077	13	early	early	ADJ
fnp-3025	1077	14	story	story	NOUN
fnp-3025	1077	15	of	of	ADP
fnp-3025	1077	16	alzheimer	alzheimer	PROPN
fnp-3025	1077	17	’s	’s	PART
fnp-3025	1077	18	disease	disease	NOUN
fnp-3025	1077	19	.	.	PUNCT
fnp-3025	1078	1	1987	1987	NUM
fnp-3025	1078	2	,	,	PUNCT
fnp-3025	1078	3	philadelphia	philadelphia	PROPN
fnp-3025	1078	4	:	:	PUNCT
fnp-3025	1078	5	lippincott	lippincott	PROPN
fnp-3025	1078	6	williams	williams	PROPN
fnp-3025	1078	7	and	and	CCONJ
fnp-3025	1078	8	wilkins	wilkin	NOUN
fnp-3025	1078	9	.	.	PUNCT
fnp-3025	1079	1	111	111	NUM
fnp-3025	1079	2	.	.	X
fnp-3025	1079	3	de	de	X
fnp-3025	1079	4	strooper	strooper	PROPN
fnp-3025	1079	5	,	,	PUNCT
fnp-3025	1079	6	b.	b.	PROPN
fnp-3025	1079	7	and	and	CCONJ
fnp-3025	1079	8	e.	e.	PROPN
fnp-3025	1079	9	karran	karran	PROPN
fnp-3025	1079	10	,	,	PUNCT
fnp-3025	1079	11	the	the	DET
fnp-3025	1079	12	cellular	cellular	ADJ
fnp-3025	1079	13	phase	phase	NOUN
fnp-3025	1079	14	of	of	ADP
fnp-3025	1079	15	alzheimer	alzheimer	PROPN
fnp-3025	1079	16	’s	’s	PART
fnp-3025	1079	17	disease	disease	NOUN
fnp-3025	1079	18	.	.	PUNCT
fnp-3025	1080	1	cell	cell	NOUN
fnp-3025	1080	2	,	,	PUNCT
fnp-3025	1080	3	2016	2016	NUM
fnp-3025	1080	4	.	.	PUNCT
fnp-3025	1081	1	164(4	164(4	NUM
fnp-3025	1081	2	):	):	PUNCT
fnp-3025	1081	3	p.	p.	NOUN
fnp-3025	1081	4	603	603	NUM
fnp-3025	1081	5	-	-	SYM
fnp-3025	1081	6	15	15	NUM
fnp-3025	1081	7	.	.	PUNCT
fnp-3025	1081	8	112	112	NUM
fnp-3025	1081	9	.	.	PUNCT
fnp-3025	1082	1	gleichman	gleichman	NOUN
fnp-3025	1082	2	,	,	PUNCT
fnp-3025	1082	3	a.j	a.j	PROPN
fnp-3025	1082	4	.	.	PROPN
fnp-3025	1082	5	and	and	CCONJ
fnp-3025	1082	6	s.t	s.t	PROPN
fnp-3025	1082	7	.	.	PROPN
fnp-3025	1082	8	carmichael	carmichael	PROPN
fnp-3025	1082	9	,	,	PUNCT
fnp-3025	1082	10	glia	glia	NOUN
fnp-3025	1082	11	in	in	ADP
fnp-3025	1082	12	neurodegeneration	neurodegeneration	NOUN
fnp-3025	1082	13	:	:	PUNCT
fnp-3025	1082	14	drivers	driver	NOUN
fnp-3025	1082	15	of	of	ADP
fnp-3025	1082	16	disease	disease	NOUN
fnp-3025	1082	17	or	or	CCONJ
fnp-3025	1082	18	along	along	ADP
fnp-3025	1082	19	for	for	ADP
fnp-3025	1082	20	the	the	DET
fnp-3025	1082	21	ride	ride	NOUN
fnp-3025	1082	22	?	?	PUNCT
fnp-3025	1083	1	neurobiol	neurobiol	PROPN
fnp-3025	1083	2	dis	dis	PROPN
fnp-3025	1083	3	,	,	PUNCT
fnp-3025	1083	4	2020	2020	NUM
fnp-3025	1083	5	.	.	PUNCT
fnp-3025	1084	1	142	142	NUM
fnp-3025	1084	2	:	:	PUNCT
fnp-3025	1084	3	p.	p.	NOUN
fnp-3025	1084	4	104957	104957	NUM
fnp-3025	1084	5	.	.	PUNCT
fnp-3025	1085	1	113	113	NUM
fnp-3025	1085	2	.	.	PUNCT
fnp-3025	1085	3	heneka	heneka	PROPN
fnp-3025	1085	4	,	,	PUNCT
fnp-3025	1085	5	m.t	m.t	PROPN
fnp-3025	1085	6	.	.	PROPN
fnp-3025	1085	7	,	,	PUNCT
fnp-3025	1085	8	et	et	PROPN
fnp-3025	1085	9	al	al	PROPN
fnp-3025	1085	10	.	.	PROPN
fnp-3025	1085	11	,	,	PUNCT
fnp-3025	1085	12	neuroinflammation	neuroinflammation	NOUN
fnp-3025	1085	13	in	in	ADP
fnp-3025	1085	14	alzheimer	alzheimer	PROPN
fnp-3025	1085	15	’s	’s	PART
fnp-3025	1085	16	disease	disease	NOUN
fnp-3025	1085	17	.	.	PUNCT
fnp-3025	1086	1	lancet	lancet	PROPN
fnp-3025	1086	2	neurol	neurol	PROPN
fnp-3025	1086	3	,	,	PUNCT
fnp-3025	1086	4	2015	2015	NUM
fnp-3025	1086	5	.	.	PUNCT
fnp-3025	1087	1	14(4	14(4	NOUN
fnp-3025	1087	2	):	):	PUNCT
fnp-3025	1087	3	p.	p.	NOUN
fnp-3025	1087	4	388	388	NUM
fnp-3025	1087	5	-	-	SYM
fnp-3025	1087	6	405	405	NUM
fnp-3025	1087	7	.	.	PUNCT
fnp-3025	1087	8	114	114	NUM
fnp-3025	1087	9	.	.	PUNCT
fnp-3025	1088	1	newcombe	newcombe	PROPN
fnp-3025	1088	2	,	,	PUNCT
fnp-3025	1088	3	e.a	e.a	PROPN
fnp-3025	1088	4	.	.	PROPN
fnp-3025	1088	5	,	,	PUNCT
fnp-3025	1088	6	et	et	PROPN
fnp-3025	1088	7	al	al	PROPN
fnp-3025	1088	8	.	.	PROPN
fnp-3025	1088	9	,	,	PUNCT
fnp-3025	1088	10	inflammation	inflammation	NOUN
fnp-3025	1088	11	:	:	PUNCT
fnp-3025	1088	12	the	the	DET
fnp-3025	1088	13	link	link	NOUN
fnp-3025	1088	14	between	between	ADP
fnp-3025	1088	15	comorbidities	comorbiditie	NOUN
fnp-3025	1088	16	,	,	PUNCT
fnp-3025	1088	17	genetics	genetic	NOUN
fnp-3025	1088	18	,	,	PUNCT
fnp-3025	1088	19	and	and	CCONJ
fnp-3025	1088	20	alzheimer	alzheimer	PROPN
fnp-3025	1088	21	’s	’s	PART
fnp-3025	1088	22	disease	disease	NOUN
fnp-3025	1088	23	.	.	PUNCT
fnp-3025	1089	1	j	j	PROPN
fnp-3025	1089	2	neuroinflammation	neuroinflammation	PROPN
fnp-3025	1089	3	,	,	PUNCT
fnp-3025	1089	4	2018	2018	NUM
fnp-3025	1089	5	.	.	PUNCT
fnp-3025	1090	1	15(1	15(1	NUM
fnp-3025	1090	2	):	):	PUNCT
fnp-3025	1090	3	p.	p.	NOUN
fnp-3025	1090	4	276	276	NUM
fnp-3025	1090	5	.	.	PUNCT
fnp-3025	1091	1	115	115	NUM
fnp-3025	1091	2	.	.	PUNCT
fnp-3025	1092	1	shi	shi	PROPN
fnp-3025	1092	2	,	,	PUNCT
fnp-3025	1092	3	y.	y.	PROPN
fnp-3025	1092	4	and	and	CCONJ
fnp-3025	1092	5	d.m	d.m	PROPN
fnp-3025	1092	6	.	.	PROPN
fnp-3025	1092	7	holtzman	holtzman	PROPN
fnp-3025	1092	8	,	,	PUNCT
fnp-3025	1092	9	interplay	interplay	NOUN
fnp-3025	1092	10	between	between	ADP
fnp-3025	1092	11	innate	innate	ADJ
fnp-3025	1092	12	immunity	immunity	NOUN
fnp-3025	1092	13	and	and	CCONJ
fnp-3025	1092	14	alzheimer	alzheimer	NOUN
fnp-3025	1092	15	disease	disease	PROPN
fnp-3025	1092	16	:	:	PUNCT
fnp-3025	1092	17	apoe	apoe	ADJ
fnp-3025	1092	18	and	and	CCONJ
fnp-3025	1092	19	trem2	trem2	NOUN
fnp-3025	1092	20	in	in	ADP
fnp-3025	1092	21	the	the	DET
fnp-3025	1092	22	spotlight	spotlight	NOUN
fnp-3025	1092	23	.	.	PUNCT
fnp-3025	1093	1	nat	nat	PROPN
fnp-3025	1093	2	rev	rev	PROPN
fnp-3025	1093	3	immunol	immunol	NOUN
fnp-3025	1093	4	,	,	PUNCT
fnp-3025	1093	5	2018	2018	NUM
fnp-3025	1093	6	.	.	PUNCT
fnp-3025	1094	1	18(12	18(12	NUM
fnp-3025	1094	2	):	):	PUNCT
fnp-3025	1094	3	p.	p.	NOUN
fnp-3025	1094	4	759	759	NUM
fnp-3025	1094	5	-	-	SYM
fnp-3025	1094	6	772	772	NUM
fnp-3025	1094	7	.	.	NOUN
fnp-3025	1095	1	116	116	NUM
fnp-3025	1095	2	.	.	PUNCT
fnp-3025	1096	1	critchley	critchley	NOUN
fnp-3025	1096	2	,	,	PUNCT
fnp-3025	1096	3	m.	m.	NOUN
fnp-3025	1096	4	,	,	PUNCT
fnp-3025	1096	5	critical	critical	ADJ
fnp-3025	1096	6	review	review	NOUN
fnp-3025	1096	7	:	:	PUNCT
fnp-3025	1096	8	the	the	DET
fnp-3025	1096	9	nature	nature	NOUN
fnp-3025	1096	10	and	and	CCONJ
fnp-3025	1096	11	significance	significance	NOUN
fnp-3025	1096	12	of	of	ADP
fnp-3025	1096	13	senile	senile	ADJ
fnp-3025	1096	14	plaques	plaque	NOUN
fnp-3025	1096	15	.	.	PUNCT
fnp-3025	1097	1	journal	journal	NOUN
fnp-3025	1097	2	of	of	ADP
fnp-3025	1097	3	neurology	neurology	NOUN
fnp-3025	1097	4	and	and	CCONJ
fnp-3025	1097	5	psychopathology	psychopathology	NOUN
fnp-3025	1097	6	,	,	PUNCT
fnp-3025	1097	7	1929	1929	NUM
fnp-3025	1097	8	.	.	PUNCT
fnp-3025	1098	1	10(38	10(38	NUM
fnp-3025	1098	2	):	):	PUNCT
fnp-3025	1098	3	p.	p.	NOUN
fnp-3025	1098	4	124	124	NUM
fnp-3025	1098	5	-	-	SYM
fnp-3025	1098	6	39	39	NUM
fnp-3025	1098	7	.	.	PUNCT
fnp-3025	1099	1	117	117	NUM
fnp-3025	1099	2	.	.	PUNCT
fnp-3025	1100	1	fischer	fischer	PROPN
fnp-3025	1100	2	,	,	PUNCT
fnp-3025	1100	3	o.	o.	PROPN
fnp-3025	1100	4	,	,	PUNCT
fnp-3025	1100	5	miliare	miliare	NOUN
fnp-3025	1100	6	nekrosen	nekrosen	PROPN
fnp-3025	1100	7	mit	mit	PROPN
fnp-3025	1101	1	drusigen	drusigen	NOUN
fnp-3025	1101	2	wucherungen	wucherungen	NOUN
fnp-3025	1101	3	der	der	PROPN
fnp-3025	1101	4	neurofibrillen	neurofibrillen	PROPN
fnp-3025	1101	5	,	,	PUNCT
fnp-3025	1101	6	eine	eine	PROPN
fnp-3025	1101	7	regelmässige	regelmässige	PROPN
fnp-3025	1101	8	veränderung	veränderung	PROPN
fnp-3025	1101	9	der	der	PROPN
fnp-3025	1101	10	hirnrinde	hirnrinde	NOUN
fnp-3025	1101	11	bei	bei	NOUN
fnp-3025	1101	12	seniler	seniler	NOUN
fnp-3025	1101	13	demenz	demenz	PROPN
fnp-3025	1101	14	.	.	PUNCT
fnp-3025	1102	1	monatsschrift	monatsschrift	PROPN
fnp-3025	1102	2	für	für	PROPN
fnp-3025	1102	3	psychiatrie	psychiatrie	PROPN
fnp-3025	1102	4	und	und	PROPN
fnp-3025	1102	5	neurologie	neurologie	NOUN
fnp-3025	1102	6	,	,	PUNCT
fnp-3025	1102	7	1907	1907	NUM
fnp-3025	1102	8	.	.	PUNCT
fnp-3025	1103	1	22	22	NUM
fnp-3025	1103	2	:	:	PUNCT
fnp-3025	1104	1	p.	p.	NOUN
fnp-3025	1104	2	361	361	NUM
fnp-3025	1104	3	-	-	SYM
fnp-3025	1104	4	372	372	NUM
fnp-3025	1104	5	.	.	NUM
fnp-3025	1104	6	118	118	NUM
fnp-3025	1104	7	.	.	PUNCT
fnp-3025	1105	1	ferraro	ferraro	PROPN
fnp-3025	1105	2	,	,	PUNCT
fnp-3025	1105	3	a.	a.	PROPN
fnp-3025	1105	4	,	,	PUNCT
fnp-3025	1105	5	the	the	DET
fnp-3025	1105	6	origin	origin	NOUN
fnp-3025	1105	7	and	and	CCONJ
fnp-3025	1105	8	formation	formation	NOUN
fnp-3025	1105	9	of	of	ADP
fnp-3025	1105	10	senile	senile	ADJ
fnp-3025	1105	11	plaques	plaque	NOUN
fnp-3025	1105	12	.	.	PUNCT
fnp-3025	1106	1	archives	archive	NOUN
fnp-3025	1106	2	of	of	ADP
fnp-3025	1106	3	neurology	neurology	NOUN
fnp-3025	1106	4	and	and	CCONJ
fnp-3025	1106	5	psychiatry	psychiatry	NOUN
fnp-3025	1106	6	,	,	PUNCT
fnp-3025	1106	7	1931	1931	NUM
fnp-3025	1106	8	.	.	PUNCT
fnp-3025	1107	1	25(5	25(5	NUM
fnp-3025	1107	2	):	):	PUNCT
fnp-3025	1108	1	p.	p.	NOUN
fnp-3025	1108	2	1042	1042	NUM
fnp-3025	1108	3	-	-	SYM
fnp-3025	1108	4	1062	1062	NUM
fnp-3025	1108	5	.	.	PUNCT
fnp-3025	1109	1	119	119	NUM
fnp-3025	1109	2	.	.	PUNCT
fnp-3025	1109	3	soniat	soniat	PROPN
fnp-3025	1109	4	,	,	PUNCT
fnp-3025	1109	5	t.l.l	t.l.l	PROPN
fnp-3025	1109	6	.	.	PUNCT
fnp-3025	1109	7	,	,	PUNCT
fnp-3025	1109	8	histogenesis	histogenesis	NOUN
fnp-3025	1109	9	of	of	ADP
fnp-3025	1109	10	senile	senile	ADJ
fnp-3025	1109	11	plaques	plaque	NOUN
fnp-3025	1109	12	.	.	PUNCT
fnp-3025	1110	1	archives	archive	NOUN
fnp-3025	1110	2	of	of	ADP
fnp-3025	1110	3	neurology	neurology	NOUN
fnp-3025	1110	4	and	and	CCONJ
fnp-3025	1110	5	psychiatry	psychiatry	NOUN
fnp-3025	1110	6	,	,	PUNCT
fnp-3025	1110	7	1941	1941	NUM
fnp-3025	1110	8	.	.	PUNCT
fnp-3025	1111	1	46(1	46(1	X
fnp-3025	1111	2	):	):	PUNCT
fnp-3025	1112	1	p.	p.	NOUN
fnp-3025	1112	2	101	101	NUM
fnp-3025	1112	3	-	-	SYM
fnp-3025	1112	4	114	114	NUM
fnp-3025	1112	5	.	.	PUNCT
fnp-3025	1112	6	120	120	NUM
fnp-3025	1112	7	.	.	PUNCT
fnp-3025	1113	1	liss	liss	PROPN
fnp-3025	1113	2	,	,	PUNCT
fnp-3025	1113	3	l.	l.	PROPN
fnp-3025	1113	4	,	,	PUNCT
fnp-3025	1113	5	senile	senile	ADJ
fnp-3025	1113	6	brain	brain	NOUN
fnp-3025	1113	7	changes	change	NOUN
fnp-3025	1113	8	,	,	PUNCT
fnp-3025	1113	9	histopathology	histopathology	NOUN
fnp-3025	1113	10	of	of	ADP
fnp-3025	1113	11	the	the	DET
fnp-3025	1113	12	ganglion	ganglion	NOUN
fnp-3025	1113	13	cells	cell	NOUN
fnp-3025	1113	14	.	.	PUNCT
fnp-3025	1114	1	j	j	PROPN
fnp-3025	1114	2	neuropathol	neuropathol	PROPN
fnp-3025	1114	3	exp	exp	PROPN
fnp-3025	1114	4	neurol	neurol	PROPN
fnp-3025	1114	5	,	,	PUNCT
fnp-3025	1114	6	1960	1960	NUM
fnp-3025	1114	7	.	.	PUNCT
fnp-3025	1115	1	19	19	NUM
fnp-3025	1115	2	:	:	PUNCT
fnp-3025	1116	1	p.	p.	NOUN
fnp-3025	1116	2	559	559	NUM
fnp-3025	1116	3	-	-	SYM
fnp-3025	1116	4	71	71	NUM
fnp-3025	1116	5	.	.	NOUN
fnp-3025	1116	6	121	121	NUM
fnp-3025	1116	7	.	.	PUNCT
fnp-3025	1117	1	bouman	bouman	PROPN
fnp-3025	1117	2	,	,	PUNCT
fnp-3025	1117	3	l.	l.	PROPN
fnp-3025	1117	4	,	,	PUNCT
fnp-3025	1117	5	senile	senile	ADJ
fnp-3025	1117	6	plaques	plaque	NOUN
fnp-3025	1117	7	.	.	PUNCT
fnp-3025	1118	1	brain	brain	NOUN
fnp-3025	1118	2	,	,	PUNCT
fnp-3025	1118	3	1934	1934	NUM
fnp-3025	1118	4	.	.	PUNCT
fnp-3025	1119	1	57(2	57(2	NUM
fnp-3025	1119	2	):	):	PUNCT
fnp-3025	1119	3	p.	p.	NOUN
fnp-3025	1119	4	128	128	NUM
fnp-3025	1119	5	-	-	SYM
fnp-3025	1119	6	142	142	NUM
fnp-3025	1119	7	.	.	PUNCT
fnp-3025	1120	1	122	122	NUM
fnp-3025	1120	2	.	.	PUNCT
fnp-3025	1121	1	kidd	kidd	PROPN
fnp-3025	1121	2	,	,	PUNCT
fnp-3025	1121	3	m.	m.	NOUN
fnp-3025	1121	4	,	,	PUNCT
fnp-3025	1121	5	alzheimer	alzheimer	PROPN
fnp-3025	1121	6	’s	’s	PART
fnp-3025	1121	7	disease	disease	NOUN
fnp-3025	1121	8	--	--	PUNCT
fnp-3025	1121	9	an	an	DET
fnp-3025	1121	10	electron	electron	NOUN
fnp-3025	1121	11	microscopical	microscopical	ADJ
fnp-3025	1121	12	study	study	NOUN
fnp-3025	1121	13	.	.	PUNCT
fnp-3025	1122	1	brain	brain	NOUN
fnp-3025	1122	2	,	,	PUNCT
fnp-3025	1122	3	1964	1964	NUM
fnp-3025	1122	4	.	.	PUNCT
fnp-3025	1123	1	87	87	NUM
fnp-3025	1123	2	:	:	PUNCT
fnp-3025	1123	3	p.	p.	NOUN
fnp-3025	1123	4	307	307	NUM
fnp-3025	1123	5	-	-	SYM
fnp-3025	1123	6	20	20	NUM
fnp-3025	1123	7	.	.	PUNCT
fnp-3025	1124	1	123	123	NUM
fnp-3025	1124	2	.	.	PUNCT
fnp-3025	1125	1	terry	terry	PROPN
fnp-3025	1125	2	,	,	PUNCT
fnp-3025	1125	3	r.d	r.d	PROPN
fnp-3025	1125	4	.	.	PROPN
fnp-3025	1125	5	,	,	PUNCT
fnp-3025	1125	6	n.k	n.k	PROPN
fnp-3025	1125	7	.	.	NOUN
fnp-3025	1125	8	gonatas	gonata	NOUN
fnp-3025	1125	9	,	,	PUNCT
fnp-3025	1125	10	and	and	CCONJ
fnp-3025	1125	11	m.	m.	PROPN
fnp-3025	1125	12	weiss	weiss	PROPN
fnp-3025	1125	13	,	,	PUNCT
fnp-3025	1125	14	ultrastructural	ultrastructural	ADJ
fnp-3025	1125	15	studies	study	NOUN
fnp-3025	1125	16	in	in	ADP
fnp-3025	1125	17	alzheimer	alzheimer	PROPN
fnp-3025	1125	18	’s	’s	PART
fnp-3025	1125	19	presenile	presenile	PROPN
fnp-3025	1125	20	dementia	dementia	PROPN
fnp-3025	1125	21	.	.	PUNCT
fnp-3025	1126	1	am	be	AUX
fnp-3025	1126	2	j	j	PROPN
fnp-3025	1126	3	pathol	pathol	NOUN
fnp-3025	1126	4	,	,	PUNCT
fnp-3025	1126	5	1964	1964	NUM
fnp-3025	1126	6	.	.	PUNCT
fnp-3025	1127	1	44	44	NUM
fnp-3025	1127	2	:	:	PUNCT
fnp-3025	1128	1	p.	p.	NOUN
fnp-3025	1128	2	269	269	NUM
fnp-3025	1128	3	-	-	SYM
fnp-3025	1128	4	97	97	NUM
fnp-3025	1128	5	.	.	PUNCT
fnp-3025	1128	6	124	124	NUM
fnp-3025	1128	7	.	.	PUNCT
fnp-3025	1129	1	blessed	bless	VERB
fnp-3025	1129	2	,	,	PUNCT
fnp-3025	1129	3	g.	g.	PROPN
fnp-3025	1129	4	,	,	PUNCT
fnp-3025	1129	5	b.e	b.e	PROPN
fnp-3025	1129	6	.	.	PROPN
fnp-3025	1129	7	tomlinson	tomlinson	PROPN
fnp-3025	1129	8	,	,	PUNCT
fnp-3025	1129	9	and	and	CCONJ
fnp-3025	1129	10	m.	m.	PROPN
fnp-3025	1129	11	roth	roth	PROPN
fnp-3025	1129	12	,	,	PUNCT
fnp-3025	1129	13	the	the	DET
fnp-3025	1129	14	association	association	NOUN
fnp-3025	1129	15	between	between	ADP
fnp-3025	1129	16	quantitative	quantitative	ADJ
fnp-3025	1129	17	measures	measure	NOUN
fnp-3025	1129	18	of	of	ADP
fnp-3025	1129	19	dementia	dementia	NOUN
fnp-3025	1129	20	and	and	CCONJ
fnp-3025	1129	21	of	of	ADP
fnp-3025	1129	22	senile	senile	ADJ
fnp-3025	1129	23	change	change	NOUN
fnp-3025	1129	24	in	in	ADP
fnp-3025	1129	25	the	the	DET
fnp-3025	1129	26	cerebral	cerebral	ADJ
fnp-3025	1129	27	grey	grey	ADJ
fnp-3025	1129	28	matter	matter	NOUN
fnp-3025	1129	29	of	of	ADP
fnp-3025	1129	30	elderly	elderly	ADJ
fnp-3025	1129	31	subjects	subject	NOUN
fnp-3025	1129	32	.	.	PUNCT
fnp-3025	1130	1	br	br	PROPN
fnp-3025	1130	2	j	j	PROPN
fnp-3025	1130	3	psychiatry	psychiatry	PROPN
fnp-3025	1130	4	,	,	PUNCT
fnp-3025	1130	5	1968	1968	NUM
fnp-3025	1130	6	.	.	PUNCT
fnp-3025	1131	1	114(512	114(512	NUM
fnp-3025	1131	2	):	):	PUNCT
fnp-3025	1132	1	p.	p.	NOUN
fnp-3025	1132	2	797	797	NUM
fnp-3025	1132	3	-	-	SYM
fnp-3025	1132	4	811	811	NUM
fnp-3025	1132	5	.	.	PUNCT
fnp-3025	1133	1	125	125	NUM
fnp-3025	1133	2	.	.	PUNCT
fnp-3025	1134	1	divry	divry	NOUN
fnp-3025	1134	2	,	,	PUNCT
fnp-3025	1134	3	p.	p.	NOUN
fnp-3025	1134	4	,	,	PUNCT
fnp-3025	1134	5	etude	etude	ADJ
fnp-3025	1134	6	histo	histo	NOUN
fnp-3025	1134	7	-	-	PUNCT
fnp-3025	1134	8	chimique	chimique	ADJ
fnp-3025	1134	9	des	des	PROPN
fnp-3025	1134	10	plaques	plaque	NOUN
fnp-3025	1134	11	séniles	sénile	NOUN
fnp-3025	1134	12	.	.	PUNCT
fnp-3025	1135	1	journal	journal	PROPN
fnp-3025	1135	2	belge	belge	PROPN
fnp-3025	1135	3	de	de	PROPN
fnp-3025	1135	4	neurologie	neurologie	X
fnp-3025	1135	5	et	et	PROPN
fnp-3025	1135	6	de	de	X
fnp-3025	1135	7	psychiatrie	psychiatrie	NOUN
fnp-3025	1135	8	,	,	PUNCT
fnp-3025	1135	9	1927	1927	NUM
fnp-3025	1135	10	.	.	PUNCT
fnp-3025	1136	1	9	9	NUM
fnp-3025	1136	2	:	:	PUNCT
fnp-3025	1136	3	p.	p.	NOUN
fnp-3025	1136	4	643	643	NUM
fnp-3025	1136	5	-	-	SYM
fnp-3025	1136	6	657	657	NUM
fnp-3025	1136	7	.	.	PUNCT
fnp-3025	1136	8	126	126	NUM
fnp-3025	1136	9	.	.	PUNCT
fnp-3025	1137	1	dickson	dickson	PROPN
fnp-3025	1137	2	,	,	PUNCT
fnp-3025	1137	3	d.w	d.w	PROPN
fnp-3025	1137	4	.	.	PROPN
fnp-3025	1137	5	,	,	PUNCT
fnp-3025	1137	6	neuropathology	neuropathology	NOUN
fnp-3025	1137	7	of	of	ADP
fnp-3025	1137	8	non	non	ADJ
fnp-3025	1137	9	-	-	ADJ
fnp-3025	1137	10	alzheimer	alzheimer	ADJ
fnp-3025	1137	11	degenerative	degenerative	ADJ
fnp-3025	1137	12	disorders	disorder	NOUN
fnp-3025	1137	13	.	.	PUNCT
fnp-3025	1138	1	int	int	PROPN
fnp-3025	1139	1	j	j	PROPN
fnp-3025	1139	2	clin	clin	PROPN
fnp-3025	1139	3	exp	exp	PROPN
fnp-3025	1139	4	pathol	pathol	NOUN
fnp-3025	1139	5	,	,	PUNCT
fnp-3025	1139	6	2009	2009	NUM
fnp-3025	1139	7	.	.	PUNCT
fnp-3025	1140	1	3(1	3(1	NUM
fnp-3025	1140	2	):	):	PUNCT
fnp-3025	1141	1	p.	p.	NOUN
fnp-3025	1141	2	1	1	NUM
fnp-3025	1141	3	-	-	SYM
fnp-3025	1141	4	23	23	NUM
fnp-3025	1141	5	.	.	PUNCT
fnp-3025	1142	1	127	127	NUM
fnp-3025	1142	2	.	.	PUNCT
fnp-3025	1143	1	dearmond	dearmond	PROPN
fnp-3025	1143	2	,	,	PUNCT
fnp-3025	1143	3	s.j	s.j	PROPN
fnp-3025	1143	4	.	.	PROPN
fnp-3025	1143	5	,	,	PUNCT
fnp-3025	1143	6	et	et	PROPN
fnp-3025	1143	7	al	al	PROPN
fnp-3025	1143	8	.	.	PROPN
fnp-3025	1143	9	,	,	PUNCT
fnp-3025	1143	10	neuropathology	neuropathology	NOUN
fnp-3025	1143	11	of	of	ADP
fnp-3025	1143	12	prion	prion	NOUN
fnp-3025	1143	13	diseases	disease	NOUN
fnp-3025	1143	14	,	,	PUNCT
fnp-3025	1143	15	in	in	ADP
fnp-3025	1143	16	prion	prion	NOUN
fnp-3025	1143	17	biology	biology	NOUN
fnp-3025	1143	18	and	and	CCONJ
fnp-3025	1143	19	diseases	disease	NOUN
fnp-3025	1143	20	,	,	PUNCT
fnp-3025	1143	21	s.b	s.b	PROPN
fnp-3025	1143	22	.	.	PROPN
fnp-3025	1143	23	prusiner	prusiner	NOUN
fnp-3025	1143	24	,	,	PUNCT
fnp-3025	1143	25	editor	editor	NOUN
fnp-3025	1143	26	.	.	PUNCT
fnp-3025	1144	1	2004	2004	NUM
fnp-3025	1144	2	,	,	PUNCT
fnp-3025	1144	3	cold	cold	ADJ
fnp-3025	1144	4	spring	spring	NOUN
fnp-3025	1144	5	harbor	harbor	NOUN
fnp-3025	1144	6	laboratory	laboratory	PROPN
fnp-3025	1144	7	press	press	PROPN
fnp-3025	1144	8	:	:	PUNCT
fnp-3025	1144	9	cold	cold	ADJ
fnp-3025	1144	10	spring	spring	NOUN
fnp-3025	1144	11	harbor	harbor	NOUN
fnp-3025	1144	12	.	.	PUNCT
fnp-3025	1145	1	p.	p.	NOUN
fnp-3025	1145	2	777	777	NUM
fnp-3025	1146	1	-	-	SYM
fnp-3025	1146	2	856	856	NUM
fnp-3025	1146	3	.	.	PUNCT
fnp-3025	1147	1	128	128	NUM
fnp-3025	1147	2	.	.	PUNCT
fnp-3025	1148	1	dearmond	dearmond	PROPN
fnp-3025	1148	2	,	,	PUNCT
fnp-3025	1148	3	s.j	s.j	PROPN
fnp-3025	1148	4	.	.	PROPN
fnp-3025	1148	5	and	and	CCONJ
fnp-3025	1148	6	s.b	s.b	PROPN
fnp-3025	1148	7	.	.	PROPN
fnp-3025	1148	8	prusiner	prusiner	NOUN
fnp-3025	1148	9	,	,	PUNCT
fnp-3025	1148	10	etiology	etiology	NOUN
fnp-3025	1148	11	and	and	CCONJ
fnp-3025	1148	12	pathogenesis	pathogenesis	NOUN
fnp-3025	1148	13	of	of	ADP
fnp-3025	1148	14	prion	prion	NOUN
fnp-3025	1148	15	diseases	disease	NOUN
fnp-3025	1148	16	.	.	PUNCT
fnp-3025	1149	1	am	be	AUX
fnp-3025	1149	2	j	j	PROPN
fnp-3025	1149	3	pathol	pathol	NOUN
fnp-3025	1149	4	,	,	PUNCT
fnp-3025	1149	5	1995	1995	NUM
fnp-3025	1149	6	.	.	PUNCT
fnp-3025	1150	1	146(4	146(4	NUM
fnp-3025	1150	2	):	):	PUNCT
fnp-3025	1151	1	p.	p.	NOUN
fnp-3025	1151	2	785	785	NUM
fnp-3025	1151	3	-	-	SYM
fnp-3025	1151	4	811	811	NUM
fnp-3025	1151	5	.	.	PUNCT
fnp-3025	1152	1	129	129	NUM
fnp-3025	1152	2	.	.	PUNCT
fnp-3025	1153	1	holton	holton	PROPN
fnp-3025	1153	2	,	,	PUNCT
fnp-3025	1153	3	j.l	j.l	PROPN
fnp-3025	1153	4	.	.	PROPN
fnp-3025	1153	5	,	,	PUNCT
fnp-3025	1153	6	et	et	PROPN
fnp-3025	1153	7	al	al	PROPN
fnp-3025	1153	8	.	.	PROPN
fnp-3025	1153	9	,	,	PUNCT
fnp-3025	1153	10	regional	regional	ADJ
fnp-3025	1153	11	distribution	distribution	NOUN
fnp-3025	1153	12	of	of	ADP
fnp-3025	1153	13	amyloid	amyloid	NOUN
fnp-3025	1153	14	-	-	PUNCT
fnp-3025	1153	15	bri	bri	NOUN
fnp-3025	1153	16	deposition	deposition	NOUN
fnp-3025	1153	17	and	and	CCONJ
fnp-3025	1153	18	its	its	PRON
fnp-3025	1153	19	association	association	NOUN
fnp-3025	1153	20	with	with	ADP
fnp-3025	1153	21	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1153	22	degeneration	degeneration	NOUN
fnp-3025	1153	23	in	in	ADP
fnp-3025	1153	24	familial	familial	ADJ
fnp-3025	1153	25	british	british	ADJ
fnp-3025	1153	26	dementia	dementia	NOUN
fnp-3025	1153	27	.	.	PUNCT
fnp-3025	1154	1	am	be	AUX
fnp-3025	1154	2	j	j	PROPN
fnp-3025	1154	3	pathol	pathol	NOUN
fnp-3025	1154	4	,	,	PUNCT
fnp-3025	1154	5	2001	2001	NUM
fnp-3025	1154	6	.	.	PUNCT
fnp-3025	1155	1	158(2	158(2	NUM
fnp-3025	1155	2	):	):	PUNCT
fnp-3025	1155	3	p.	p.	NOUN
fnp-3025	1155	4	515	515	NUM
fnp-3025	1155	5	-	-	SYM
fnp-3025	1155	6	26	26	NUM
fnp-3025	1155	7	.	.	PUNCT
fnp-3025	1155	8	130	130	NUM
fnp-3025	1155	9	.	.	PUNCT
fnp-3025	1156	1	vidal	vidal	PROPN
fnp-3025	1156	2	,	,	PUNCT
fnp-3025	1156	3	r.	r.	PROPN
fnp-3025	1156	4	,	,	PUNCT
fnp-3025	1156	5	et	et	PROPN
fnp-3025	1156	6	al	al	PROPN
fnp-3025	1156	7	.	.	PROPN
fnp-3025	1156	8	,	,	PUNCT
fnp-3025	1156	9	a	a	DET
fnp-3025	1156	10	stop	stop	VERB
fnp-3025	1156	11	-	-	PUNCT
fnp-3025	1156	12	codon	codon	ADJ
fnp-3025	1156	13	mutation	mutation	NOUN
fnp-3025	1156	14	in	in	ADP
fnp-3025	1156	15	the	the	DET
fnp-3025	1156	16	bri	bri	NOUN
fnp-3025	1156	17	gene	gene	NOUN
fnp-3025	1156	18	associated	associate	VERB
fnp-3025	1156	19	with	with	ADP
fnp-3025	1156	20	familial	familial	ADJ
fnp-3025	1156	21	british	british	ADJ
fnp-3025	1156	22	dementia	dementia	NOUN
fnp-3025	1156	23	.	.	PUNCT
fnp-3025	1157	1	nature	nature	NOUN
fnp-3025	1157	2	,	,	PUNCT
fnp-3025	1157	3	1999	1999	NUM
fnp-3025	1157	4	.	.	PUNCT
fnp-3025	1158	1	399(6738	399(6738	NUM
fnp-3025	1158	2	):	):	PUNCT
fnp-3025	1158	3	p.	p.	NOUN
fnp-3025	1158	4	776	776	NUM
fnp-3025	1158	5	-	-	SYM
fnp-3025	1158	6	81	81	NUM
fnp-3025	1158	7	.	.	PUNCT
fnp-3025	1159	1	131	131	NUM
fnp-3025	1159	2	.	.	PUNCT
fnp-3025	1160	1	holton	holton	PROPN
fnp-3025	1160	2	,	,	PUNCT
fnp-3025	1160	3	j.l	j.l	PROPN
fnp-3025	1160	4	.	.	PROPN
fnp-3025	1160	5	,	,	PUNCT
fnp-3025	1160	6	et	et	PROPN
fnp-3025	1160	7	al	al	PROPN
fnp-3025	1160	8	.	.	PROPN
fnp-3025	1160	9	,	,	PUNCT
fnp-3025	1160	10	familial	familial	ADJ
fnp-3025	1160	11	danish	danish	ADJ
fnp-3025	1160	12	dementia	dementia	NOUN
fnp-3025	1160	13	:	:	PUNCT
fnp-3025	1160	14	a	a	DET
fnp-3025	1160	15	novel	novel	ADJ
fnp-3025	1160	16	form	form	NOUN
fnp-3025	1160	17	of	of	ADP
fnp-3025	1160	18	cerebral	cerebral	ADJ
fnp-3025	1160	19	amyloidosis	amyloidosis	NOUN
fnp-3025	1160	20	associated	associate	VERB
fnp-3025	1160	21	with	with	ADP
fnp-3025	1160	22	deposition	deposition	NOUN
fnp-3025	1160	23	of	of	ADP
fnp-3025	1160	24	both	both	PRON
fnp-3025	1160	25	amyloid	amyloid	NOUN
fnp-3025	1160	26	-	-	PUNCT
fnp-3025	1160	27	dan	dan	PROPN
fnp-3025	1160	28	and	and	CCONJ
fnp-3025	1160	29	amyloid	amyloid	NOUN
fnp-3025	1160	30	-	-	PUNCT
fnp-3025	1160	31	beta	beta	NOUN
fnp-3025	1160	32	.	.	PUNCT
fnp-3025	1161	1	j	j	PROPN
fnp-3025	1161	2	neuropathol	neuropathol	PROPN
fnp-3025	1161	3	exp	exp	PROPN
fnp-3025	1161	4	neurol	neurol	PROPN
fnp-3025	1161	5	,	,	PUNCT
fnp-3025	1161	6	2002	2002	NUM
fnp-3025	1161	7	.	.	PUNCT
fnp-3025	1162	1	61(3	61(3	NUM
fnp-3025	1162	2	):	):	PUNCT
fnp-3025	1162	3	p.	p.	NOUN
fnp-3025	1162	4	254	254	NUM
fnp-3025	1162	5	-	-	SYM
fnp-3025	1162	6	67	67	NUM
fnp-3025	1162	7	.	.	PUNCT
fnp-3025	1163	1	132	132	NUM
fnp-3025	1163	2	.	.	PUNCT
fnp-3025	1164	1	vidal	vidal	PROPN
fnp-3025	1164	2	,	,	PUNCT
fnp-3025	1164	3	r.	r.	PROPN
fnp-3025	1164	4	,	,	PUNCT
fnp-3025	1164	5	et	et	PROPN
fnp-3025	1164	6	al	al	PROPN
fnp-3025	1164	7	.	.	PROPN
fnp-3025	1164	8	,	,	PUNCT
fnp-3025	1164	9	a	a	DET
fnp-3025	1164	10	decamer	decamer	ADJ
fnp-3025	1164	11	duplication	duplication	NOUN
fnp-3025	1164	12	in	in	ADP
fnp-3025	1164	13	the	the	DET
fnp-3025	1164	14	3	3	NUM
fnp-3025	1164	15	’	'	PUNCT
fnp-3025	1164	16	region	region	NOUN
fnp-3025	1164	17	of	of	ADP
fnp-3025	1164	18	the	the	DET
fnp-3025	1164	19	bri	bri	NOUN
fnp-3025	1164	20	gene	gene	NOUN
fnp-3025	1164	21	originates	originate	VERB
fnp-3025	1164	22	an	an	DET
fnp-3025	1164	23	amyloid	amyloid	NOUN
fnp-3025	1164	24	peptide	peptide	NOUN
fnp-3025	1164	25	that	that	PRON
fnp-3025	1164	26	is	be	AUX
fnp-3025	1164	27	associated	associate	VERB
fnp-3025	1164	28	with	with	ADP
fnp-3025	1164	29	dementia	dementia	NOUN
fnp-3025	1164	30	in	in	ADP
fnp-3025	1164	31	a	a	DET
fnp-3025	1164	32	danish	danish	NOUN
fnp-3025	1164	33	kindred	kindre	VERB
fnp-3025	1164	34	.	.	PUNCT
fnp-3025	1165	1	proc	proc	PROPN
fnp-3025	1165	2	natl	natl	PROPN
fnp-3025	1165	3	acad	acad	PROPN
fnp-3025	1165	4	sci	sci	PROPN
fnp-3025	1165	5	u	u	PROPN
fnp-3025	1165	6	s	s	PROPN
fnp-3025	1165	7	a	a	PRON
fnp-3025	1165	8	,	,	PUNCT
fnp-3025	1165	9	2000	2000	NUM
fnp-3025	1165	10	.	.	PUNCT
fnp-3025	1166	1	97(9	97(9	NOUN
fnp-3025	1166	2	):	):	PUNCT
fnp-3025	1167	1	p.	p.	NOUN
fnp-3025	1167	2	4920	4920	NUM
fnp-3025	1167	3	-	-	SYM
fnp-3025	1167	4	5	5	NUM
fnp-3025	1167	5	.	.	NUM
fnp-3025	1167	6	133	133	NUM
fnp-3025	1167	7	.	.	PUNCT
fnp-3025	1167	8	serrano	serrano	PROPN
fnp-3025	1167	9	-	-	PUNCT
fnp-3025	1167	10	pozo	pozo	PROPN
fnp-3025	1167	11	,	,	PUNCT
fnp-3025	1167	12	a.	a.	PROPN
fnp-3025	1167	13	,	,	PUNCT
fnp-3025	1167	14	et	et	PROPN
fnp-3025	1167	15	al	al	PROPN
fnp-3025	1167	16	.	.	PROPN
fnp-3025	1167	17	,	,	PUNCT
fnp-3025	1167	18	neuropathological	neuropathological	ADJ
fnp-3025	1167	19	alterations	alteration	NOUN
fnp-3025	1167	20	in	in	ADP
fnp-3025	1167	21	alzheimer	alzheimer	PROPN
fnp-3025	1167	22	disease	disease	PROPN
fnp-3025	1167	23	.	.	PUNCT
fnp-3025	1168	1	cold	cold	ADJ
fnp-3025	1168	2	spring	spring	NOUN
fnp-3025	1168	3	harb	harb	PROPN
fnp-3025	1168	4	perspect	perspect	PROPN
fnp-3025	1168	5	med	med	PROPN
fnp-3025	1168	6	,	,	PUNCT
fnp-3025	1168	7	2011	2011	NUM
fnp-3025	1168	8	.	.	PUNCT
fnp-3025	1169	1	1(1	1(1	NUM
fnp-3025	1169	2	):	):	PUNCT
fnp-3025	1169	3	p.	p.	PROPN
fnp-3025	1169	4	a006189	a006189	PROPN
fnp-3025	1169	5	.	.	PUNCT
fnp-3025	1170	1	134	134	NUM
fnp-3025	1170	2	.	.	PUNCT
fnp-3025	1170	3	steiner	steiner	PROPN
fnp-3025	1170	4	,	,	PUNCT
fnp-3025	1170	5	h.	h.	PROPN
fnp-3025	1170	6	,	,	PUNCT
fnp-3025	1170	7	et	et	PROPN
fnp-3025	1170	8	al	al	PROPN
fnp-3025	1170	9	.	.	PROPN
fnp-3025	1170	10	,	,	PUNCT
fnp-3025	1170	11	a	a	DET
fnp-3025	1170	12	pathogenic	pathogenic	ADJ
fnp-3025	1170	13	presenilin-1	presenilin-1	NUM
fnp-3025	1170	14	deletion	deletion	NOUN
fnp-3025	1170	15	causes	cause	VERB
fnp-3025	1170	16	abberrant	abberrant	PROPN
fnp-3025	1170	17	abeta	abeta	PROPN
fnp-3025	1170	18	42	42	NUM
fnp-3025	1170	19	production	production	NOUN
fnp-3025	1170	20	in	in	ADP
fnp-3025	1170	21	the	the	DET
fnp-3025	1170	22	absence	absence	NOUN
fnp-3025	1170	23	of	of	ADP
fnp-3025	1170	24	congophilic	congophilic	ADJ
fnp-3025	1170	25	amyloid	amyloid	NOUN
fnp-3025	1170	26	plaques	plaque	NOUN
fnp-3025	1170	27	.	.	PUNCT
fnp-3025	1171	1	j	j	PROPN
fnp-3025	1171	2	biol	biol	PROPN
fnp-3025	1171	3	chem	chem	NOUN
fnp-3025	1171	4	,	,	PUNCT
fnp-3025	1171	5	2001	2001	NUM
fnp-3025	1171	6	.	.	PUNCT
fnp-3025	1172	1	276(10	276(10	NUM
fnp-3025	1172	2	):	):	PUNCT
fnp-3025	1173	1	p.	p.	NOUN
fnp-3025	1173	2	7233	7233	NUM
fnp-3025	1173	3	-	-	SYM
fnp-3025	1173	4	9	9	NUM
fnp-3025	1173	5	.	.	NOUN
fnp-3025	1173	6	135	135	NUM
fnp-3025	1173	7	.	.	PUNCT
fnp-3025	1174	1	iwatsubo	iwatsubo	ADJ
fnp-3025	1174	2	,	,	PUNCT
fnp-3025	1174	3	t.	t.	PROPN
fnp-3025	1174	4	,	,	PUNCT
fnp-3025	1174	5	et	et	PROPN
fnp-3025	1174	6	al	al	PROPN
fnp-3025	1174	7	.	.	PROPN
fnp-3025	1174	8	,	,	PUNCT
fnp-3025	1174	9	full	full	ADJ
fnp-3025	1174	10	-	-	PUNCT
fnp-3025	1174	11	length	length	NOUN
fnp-3025	1174	12	amyloid	amyloid	NOUN
fnp-3025	1174	13	-	-	PUNCT
fnp-3025	1174	14	beta	beta	NOUN
fnp-3025	1174	15	(	(	PUNCT
fnp-3025	1174	16	1	1	NUM
fnp-3025	1174	17	-	-	NUM
fnp-3025	1174	18	42(43	42(43	NUM
fnp-3025	1174	19	)	)	PUNCT
fnp-3025	1174	20	)	)	PUNCT
fnp-3025	1174	21	and	and	CCONJ
fnp-3025	1174	22	amino	amino	NOUN
fnp-3025	1174	23	-	-	PUNCT
fnp-3025	1174	24	terminally	terminally	ADV
fnp-3025	1174	25	modified	modified	ADJ
fnp-3025	1174	26	and	and	CCONJ
fnp-3025	1174	27	truncated	truncated	ADJ
fnp-3025	1174	28	amyloid	amyloid	NOUN
fnp-3025	1174	29	-	-	PUNCT
fnp-3025	1174	30	beta	beta	NOUN
fnp-3025	1174	31	42(43	42(43	NOUN
fnp-3025	1174	32	)	)	PUNCT
fnp-3025	1174	33	deposit	deposit	NOUN
fnp-3025	1174	34	in	in	ADP
fnp-3025	1174	35	diffuse	diffuse	ADJ
fnp-3025	1174	36	plaques	plaque	NOUN
fnp-3025	1174	37	.	.	PUNCT
fnp-3025	1175	1	am	be	AUX
fnp-3025	1175	2	j	j	PROPN
fnp-3025	1175	3	pathol	pathol	NOUN
fnp-3025	1175	4	,	,	PUNCT
fnp-3025	1175	5	1996	1996	NUM
fnp-3025	1175	6	.	.	PUNCT
fnp-3025	1176	1	149(6	149(6	NUM
fnp-3025	1176	2	):	):	PUNCT
fnp-3025	1176	3	p.	p.	NOUN
fnp-3025	1176	4	1823	1823	NUM
fnp-3025	1176	5	-	-	SYM
fnp-3025	1176	6	30	30	NUM
fnp-3025	1176	7	.	.	PUNCT
fnp-3025	1177	1	136	136	NUM
fnp-3025	1177	2	.	.	PUNCT
fnp-3025	1178	1	lalowski	lalowski	ADJ
fnp-3025	1178	2	,	,	PUNCT
fnp-3025	1178	3	m.	m.	NOUN
fnp-3025	1178	4	,	,	PUNCT
fnp-3025	1178	5	et	et	PROPN
fnp-3025	1178	6	al	al	PROPN
fnp-3025	1178	7	.	.	PROPN
fnp-3025	1178	8	,	,	PUNCT
fnp-3025	1178	9	the	the	DET
fnp-3025	1178	10	"	"	PUNCT
fnp-3025	1178	11	nonamyloidogenic	nonamyloidogenic	ADJ
fnp-3025	1178	12	"	"	PUNCT
fnp-3025	1178	13	p3	p3	NOUN
fnp-3025	1178	14	fragment	fragment	NOUN
fnp-3025	1178	15	(	(	PUNCT
fnp-3025	1178	16	amyloid	amyloid	PROPN
fnp-3025	1178	17	beta17	beta17	PROPN
fnp-3025	1178	18	-	-	PUNCT
fnp-3025	1178	19	42	42	NUM
fnp-3025	1178	20	)	)	PUNCT
fnp-3025	1178	21	is	be	AUX
fnp-3025	1178	22	a	a	DET
fnp-3025	1178	23	major	major	ADJ
fnp-3025	1178	24	constituent	constituent	NOUN
fnp-3025	1178	25	of	of	ADP
fnp-3025	1178	26	down	down	NOUN
fnp-3025	1178	27	’s	’s	PART
fnp-3025	1178	28	syndrome	syndrome	PROPN
fnp-3025	1178	29	cerebellar	cerebellar	ADJ
fnp-3025	1178	30	preamyloid	preamyloid	PROPN
fnp-3025	1178	31	.	.	PUNCT
fnp-3025	1179	1	j	j	PROPN
fnp-3025	1179	2	biol	biol	PROPN
fnp-3025	1179	3	chem	chem	NOUN
fnp-3025	1179	4	,	,	PUNCT
fnp-3025	1179	5	1996	1996	NUM
fnp-3025	1179	6	.	.	PUNCT
fnp-3025	1180	1	271(52	271(52	NUM
fnp-3025	1180	2	):	):	PUNCT
fnp-3025	1180	3	p.	p.	NOUN
fnp-3025	1180	4	33623	33623	NUM
fnp-3025	1180	5	-	-	SYM
fnp-3025	1180	6	31	31	NUM
fnp-3025	1180	7	.	.	PUNCT
fnp-3025	1180	8	137	137	NUM
fnp-3025	1180	9	.	.	PUNCT
fnp-3025	1181	1	the	the	DET
fnp-3025	1181	2	american	american	PROPN
fnp-3025	1181	3	heritage	heritage	PROPN
fnp-3025	1181	4	dictionary	dictionary	NOUN
fnp-3025	1181	5	of	of	ADP
fnp-3025	1181	6	the	the	DET
fnp-3025	1181	7	english	english	ADJ
fnp-3025	1181	8	language	language	NOUN
fnp-3025	1181	9	.	.	PUNCT
fnp-3025	1182	1	2011	2011	NUM
fnp-3025	1182	2	,	,	PUNCT
fnp-3025	1182	3	houghton	houghton	PROPN
fnp-3025	1182	4	mifflin	mifflin	PROPN
fnp-3025	1182	5	harcourt	harcourt	PROPN
fnp-3025	1182	6	:	:	PUNCT
fnp-3025	1182	7	boston	boston	PROPN
fnp-3025	1182	8	,	,	PUNCT
fnp-3025	1182	9	ma	ma	PROPN
fnp-3025	1182	10	.	.	PROPN
fnp-3025	1182	11	138	138	NUM
fnp-3025	1182	12	.	.	PUNCT
fnp-3025	1183	1	hauw	hauw	PROPN
fnp-3025	1183	2	,	,	PUNCT
fnp-3025	1183	3	j.-j	j.-j	PROPN
fnp-3025	1183	4	.	.	PROPN
fnp-3025	1183	5	and	and	CCONJ
fnp-3025	1183	6	c.	c.	PROPN
fnp-3025	1183	7	duyckaerts	duyckaerts	PROPN
fnp-3025	1183	8	,	,	PUNCT
fnp-3025	1183	9	alzheimer	alzheimer	PROPN
fnp-3025	1183	10	’s	’s	PART
fnp-3025	1183	11	disease	disease	NOUN
fnp-3025	1183	12	,	,	PUNCT
fnp-3025	1183	13	in	in	ADP
fnp-3025	1183	14	pathology	pathology	NOUN
fnp-3025	1183	15	of	of	ADP
fnp-3025	1183	16	the	the	DET
fnp-3025	1183	17	aging	age	VERB
fnp-3025	1183	18	human	human	ADJ
fnp-3025	1183	19	nervous	nervous	ADJ
fnp-3025	1183	20	system	system	NOUN
fnp-3025	1183	21	,	,	PUNCT
fnp-3025	1183	22	s.	s.	PROPN
fnp-3025	1183	23	duckett	duckett	PROPN
fnp-3025	1183	24	and	and	CCONJ
fnp-3025	1183	25	j.c	j.c	PROPN
fnp-3025	1183	26	.	.	PROPN
fnp-3025	1183	27	de	de	PROPN
fnp-3025	1183	28	la	la	X
fnp-3025	1183	29	torre	torre	PROPN
fnp-3025	1183	30	,	,	PUNCT
fnp-3025	1183	31	editors	editor	NOUN
fnp-3025	1183	32	.	.	PUNCT
fnp-3025	1184	1	2001	2001	NUM
fnp-3025	1184	2	,	,	PUNCT
fnp-3025	1184	3	oxford	oxford	PROPN
fnp-3025	1184	4	university	university	PROPN
fnp-3025	1184	5	press	press	NOUN
fnp-3025	1184	6	:	:	PUNCT
fnp-3025	1184	7	new	new	PROPN
fnp-3025	1184	8	york	york	PROPN
fnp-3025	1184	9	.	.	PUNCT
fnp-3025	1185	1	p.	p.	NOUN
fnp-3025	1185	2	207	207	NUM
fnp-3025	1185	3	-	-	SYM
fnp-3025	1185	4	263	263	NUM
fnp-3025	1185	5	.	.	PUNCT
fnp-3025	1186	1	139	139	NUM
fnp-3025	1186	2	.	.	PUNCT
fnp-3025	1187	1	dickson	dickson	PROPN
fnp-3025	1187	2	,	,	PUNCT
fnp-3025	1187	3	d.w	d.w	PROPN
fnp-3025	1187	4	.	.	PROPN
fnp-3025	1187	5	,	,	PUNCT
fnp-3025	1187	6	the	the	DET
fnp-3025	1187	7	pathogenesis	pathogenesis	NOUN
fnp-3025	1187	8	of	of	ADP
fnp-3025	1187	9	senile	senile	ADJ
fnp-3025	1187	10	plaques	plaque	NOUN
fnp-3025	1187	11	.	.	PUNCT
fnp-3025	1188	1	j	j	PROPN
fnp-3025	1188	2	neuropathol	neuropathol	PROPN
fnp-3025	1188	3	exp	exp	PROPN
fnp-3025	1188	4	neurol	neurol	NOUN
fnp-3025	1188	5	,	,	PUNCT
fnp-3025	1188	6	1997	1997	NUM
fnp-3025	1188	7	.	.	PUNCT
fnp-3025	1189	1	56(4	56(4	NUM
fnp-3025	1189	2	):	):	PUNCT
fnp-3025	1189	3	p.	p.	NOUN
fnp-3025	1189	4	321	321	NUM
fnp-3025	1189	5	-	-	SYM
fnp-3025	1189	6	39	39	NUM
fnp-3025	1189	7	.	.	PUNCT
fnp-3025	1190	1	140	140	NUM
fnp-3025	1190	2	.	.	PUNCT
fnp-3025	1191	1	cupidi	cupidi	PROPN
fnp-3025	1191	2	,	,	PUNCT
fnp-3025	1191	3	c.	c.	PROPN
fnp-3025	1191	4	,	,	PUNCT
fnp-3025	1191	5	et	et	PROPN
fnp-3025	1191	6	al	al	PROPN
fnp-3025	1191	7	.	.	PROPN
fnp-3025	1191	8	,	,	PUNCT
fnp-3025	1191	9	neocortical	neocortical	ADJ
fnp-3025	1191	10	variation	variation	NOUN
fnp-3025	1191	11	of	of	ADP
fnp-3025	1191	12	abeta	abeta	ADJ
fnp-3025	1191	13	load	load	NOUN
fnp-3025	1191	14	in	in	ADP
fnp-3025	1191	15	fully	fully	ADV
fnp-3025	1191	16	expressed	express	VERB
fnp-3025	1191	17	,	,	PUNCT
fnp-3025	1191	18	pure	pure	ADJ
fnp-3025	1191	19	alzheimer	alzheimer	PROPN
fnp-3025	1191	20	’s	’s	PART
fnp-3025	1191	21	disease	disease	NOUN
fnp-3025	1191	22	.	.	PUNCT
fnp-3025	1192	1	j	j	PROPN
fnp-3025	1192	2	alzheimers	alzheimers	PROPN
fnp-3025	1192	3	dis	dis	PROPN
fnp-3025	1192	4	,	,	PUNCT
fnp-3025	1192	5	2010	2010	NUM
fnp-3025	1192	6	.	.	PUNCT
fnp-3025	1193	1	19(1	19(1	NUM
fnp-3025	1193	2	):	):	PUNCT
fnp-3025	1194	1	p.	p.	NOUN
fnp-3025	1194	2	57	57	NUM
fnp-3025	1194	3	-	-	SYM
fnp-3025	1194	4	68	68	NUM
fnp-3025	1194	5	.	.	PUNCT
fnp-3025	1194	6	141	141	NUM
fnp-3025	1194	7	.	.	PUNCT
fnp-3025	1195	1	rogers	rogers	PROPN
fnp-3025	1195	2	,	,	PUNCT
fnp-3025	1195	3	j.	j.	PROPN
fnp-3025	1195	4	and	and	CCONJ
fnp-3025	1195	5	j.h	j.h	PROPN
fnp-3025	1195	6	.	.	PROPN
fnp-3025	1195	7	morrison	morrison	PROPN
fnp-3025	1195	8	,	,	PUNCT
fnp-3025	1195	9	quantitative	quantitative	ADJ
fnp-3025	1195	10	morphology	morphology	NOUN
fnp-3025	1195	11	and	and	CCONJ
fnp-3025	1195	12	regional	regional	ADJ
fnp-3025	1195	13	and	and	CCONJ
fnp-3025	1195	14	laminar	laminar	ADJ
fnp-3025	1195	15	distributions	distribution	NOUN
fnp-3025	1195	16	of	of	ADP
fnp-3025	1195	17	senile	senile	ADJ
fnp-3025	1195	18	plaques	plaque	NOUN
fnp-3025	1195	19	in	in	ADP
fnp-3025	1195	20	alzheimer	alzheimer	PROPN
fnp-3025	1195	21	’s	’s	PART
fnp-3025	1195	22	disease	disease	NOUN
fnp-3025	1195	23	.	.	PUNCT
fnp-3025	1196	1	j	j	PROPN
fnp-3025	1196	2	neurosci	neurosci	PROPN
fnp-3025	1196	3	,	,	PUNCT
fnp-3025	1196	4	1985	1985	NUM
fnp-3025	1196	5	.	.	PUNCT
fnp-3025	1197	1	5(10	5(10	NUM
fnp-3025	1197	2	):	):	PUNCT
fnp-3025	1197	3	p.	p.	NOUN
fnp-3025	1197	4	2801	2801	NUM
fnp-3025	1197	5	-	-	SYM
fnp-3025	1197	6	8	8	NUM
fnp-3025	1197	7	.	.	NUM
fnp-3025	1198	1	142	142	NUM
fnp-3025	1198	2	.	.	PUNCT
fnp-3025	1199	1	bero	bero	PROPN
fnp-3025	1199	2	,	,	PUNCT
fnp-3025	1199	3	a.w	a.w	PROPN
fnp-3025	1199	4	.	.	PROPN
fnp-3025	1199	5	,	,	PUNCT
fnp-3025	1199	6	et	et	PROPN
fnp-3025	1199	7	al	al	PROPN
fnp-3025	1199	8	.	.	PROPN
fnp-3025	1199	9	,	,	PUNCT
fnp-3025	1199	10	neuronal	neuronal	ADJ
fnp-3025	1199	11	activity	activity	NOUN
fnp-3025	1199	12	regulates	regulate	VERB
fnp-3025	1199	13	the	the	DET
fnp-3025	1199	14	regional	regional	ADJ
fnp-3025	1199	15	vulnerability	vulnerability	NOUN
fnp-3025	1199	16	to	to	ADP
fnp-3025	1199	17	amyloid	amyloid	NOUN
fnp-3025	1199	18	-	-	PUNCT
fnp-3025	1199	19	beta	beta	ADJ
fnp-3025	1199	20	deposition	deposition	NOUN
fnp-3025	1199	21	.	.	PUNCT
fnp-3025	1200	1	nat	nat	PROPN
fnp-3025	1200	2	neurosci	neurosci	PROPN
fnp-3025	1200	3	,	,	PUNCT
fnp-3025	1200	4	2011	2011	NUM
fnp-3025	1200	5	.	.	PUNCT
fnp-3025	1201	1	14(6	14(6	NOUN
fnp-3025	1201	2	):	):	PUNCT
fnp-3025	1202	1	p.	p.	NOUN
fnp-3025	1202	2	750	750	NUM
fnp-3025	1202	3	-	-	SYM
fnp-3025	1202	4	6	6	NUM
fnp-3025	1202	5	.	.	X
fnp-3025	1202	6	143	143	NUM
fnp-3025	1202	7	.	.	PUNCT
fnp-3025	1203	1	wisniewski	wisniewski	PROPN
fnp-3025	1203	2	,	,	PUNCT
fnp-3025	1203	3	h.m	h.m	PROPN
fnp-3025	1203	4	.	.	PROPN
fnp-3025	1203	5	,	,	PUNCT
fnp-3025	1203	6	et	et	PROPN
fnp-3025	1203	7	al	al	PROPN
fnp-3025	1203	8	.	.	PROPN
fnp-3025	1203	9	,	,	PUNCT
fnp-3025	1203	10	spectrum	spectrum	NOUN
fnp-3025	1203	11	of	of	ADP
fnp-3025	1203	12	morphological	morphological	ADJ
fnp-3025	1203	13	appearance	appearance	NOUN
fnp-3025	1203	14	of	of	ADP
fnp-3025	1203	15	amyloid	amyloid	NOUN
fnp-3025	1203	16	deposits	deposit	NOUN
fnp-3025	1203	17	in	in	ADP
fnp-3025	1203	18	alzheimer	alzheimer	PROPN
fnp-3025	1203	19	’s	’s	PART
fnp-3025	1203	20	disease	disease	NOUN
fnp-3025	1203	21	.	.	PUNCT
fnp-3025	1204	1	acta	acta	PROPN
fnp-3025	1204	2	neuropathol	neuropathol	PROPN
fnp-3025	1204	3	,	,	PUNCT
fnp-3025	1204	4	1989	1989	NUM
fnp-3025	1204	5	.	.	PUNCT
fnp-3025	1205	1	78(4	78(4	NUM
fnp-3025	1205	2	):	):	PUNCT
fnp-3025	1205	3	p.	p.	NOUN
fnp-3025	1205	4	337	337	NUM
fnp-3025	1205	5	-	-	SYM
fnp-3025	1205	6	47	47	NUM
fnp-3025	1205	7	.	.	PUNCT
fnp-3025	1206	1	144	144	NUM
fnp-3025	1206	2	.	.	PUNCT
fnp-3025	1207	1	thal	thal	PROPN
fnp-3025	1207	2	,	,	PUNCT
fnp-3025	1207	3	d.r	d.r	PROPN
fnp-3025	1207	4	.	.	PROPN
fnp-3025	1207	5	,	,	PUNCT
fnp-3025	1207	6	et	et	PROPN
fnp-3025	1207	7	al	al	PROPN
fnp-3025	1207	8	.	.	PROPN
fnp-3025	1207	9	,	,	PUNCT
fnp-3025	1207	10	the	the	DET
fnp-3025	1207	11	development	development	NOUN
fnp-3025	1207	12	of	of	ADP
fnp-3025	1207	13	amyloid	amyloid	NOUN
fnp-3025	1207	14	beta	beta	NOUN
fnp-3025	1207	15	protein	protein	NOUN
fnp-3025	1207	16	deposits	deposit	NOUN
fnp-3025	1207	17	in	in	ADP
fnp-3025	1207	18	the	the	DET
fnp-3025	1207	19	aged	aged	ADJ
fnp-3025	1207	20	brain	brain	NOUN
fnp-3025	1207	21	.	.	PUNCT
fnp-3025	1208	1	sci	sci	PROPN
fnp-3025	1208	2	aging	age	VERB
fnp-3025	1208	3	knowledge	knowledge	NOUN
fnp-3025	1208	4	environ	environ	PROPN
fnp-3025	1208	5	,	,	PUNCT
fnp-3025	1208	6	2006	2006	NUM
fnp-3025	1208	7	.	.	PUNCT
fnp-3025	1209	1	2006(6	2006(6	NUM
fnp-3025	1209	2	):	):	PUNCT
fnp-3025	1209	3	p.	p.	PROPN
fnp-3025	1209	4	re1	re1	PROPN
fnp-3025	1209	5	.	.	PROPN
fnp-3025	1210	1	145	145	NUM
fnp-3025	1210	2	.	.	PUNCT
fnp-3025	1211	1	thal	thal	PROPN
fnp-3025	1211	2	,	,	PUNCT
fnp-3025	1211	3	d.r	d.r	PROPN
fnp-3025	1211	4	.	.	PROPN
fnp-3025	1211	5	,	,	PUNCT
fnp-3025	1211	6	et	et	PROPN
fnp-3025	1211	7	al	al	PROPN
fnp-3025	1211	8	.	.	PROPN
fnp-3025	1211	9	,	,	PUNCT
fnp-3025	1211	10	phases	phase	NOUN
fnp-3025	1211	11	of	of	ADP
fnp-3025	1211	12	a	a	DET
fnp-3025	1211	13	beta	beta	NOUN
fnp-3025	1211	14	-	-	PUNCT
fnp-3025	1211	15	deposition	deposition	NOUN
fnp-3025	1211	16	in	in	ADP
fnp-3025	1211	17	the	the	DET
fnp-3025	1211	18	human	human	ADJ
fnp-3025	1211	19	brain	brain	NOUN
fnp-3025	1211	20	and	and	CCONJ
fnp-3025	1211	21	its	its	PRON
fnp-3025	1211	22	relevance	relevance	NOUN
fnp-3025	1211	23	for	for	ADP
fnp-3025	1211	24	the	the	DET
fnp-3025	1211	25	development	development	NOUN
fnp-3025	1211	26	of	of	ADP
fnp-3025	1211	27	ad	ad	NOUN
fnp-3025	1211	28	.	.	PUNCT
fnp-3025	1211	29	neurology	neurology	NOUN
fnp-3025	1211	30	,	,	PUNCT
fnp-3025	1211	31	2002	2002	NUM
fnp-3025	1211	32	.	.	PUNCT
fnp-3025	1212	1	58(12	58(12	NUM
fnp-3025	1212	2	):	):	PUNCT
fnp-3025	1212	3	p.	p.	NOUN
fnp-3025	1212	4	1791	1791	NUM
fnp-3025	1212	5	-	-	SYM
fnp-3025	1212	6	800	800	NUM
fnp-3025	1212	7	.	.	PUNCT
fnp-3025	1213	1	146	146	NUM
fnp-3025	1213	2	.	.	PUNCT
fnp-3025	1214	1	braak	braak	PROPN
fnp-3025	1214	2	,	,	PUNCT
fnp-3025	1214	3	h.	h.	PROPN
fnp-3025	1214	4	,	,	PUNCT
fnp-3025	1214	5	et	et	PROPN
fnp-3025	1214	6	al	al	PROPN
fnp-3025	1214	7	.	.	PROPN
fnp-3025	1214	8	,	,	PUNCT
fnp-3025	1214	9	stages	stage	NOUN
fnp-3025	1214	10	of	of	ADP
fnp-3025	1214	11	the	the	DET
fnp-3025	1214	12	pathologic	pathologic	ADJ
fnp-3025	1214	13	process	process	NOUN
fnp-3025	1214	14	in	in	ADP
fnp-3025	1214	15	alzheimer	alzheimer	PROPN
fnp-3025	1214	16	disease	disease	NOUN
fnp-3025	1214	17	:	:	PUNCT
fnp-3025	1214	18	age	age	NOUN
fnp-3025	1214	19	categories	category	NOUN
fnp-3025	1214	20	from	from	ADP
fnp-3025	1214	21	1	1	NUM
fnp-3025	1214	22	to	to	PART
fnp-3025	1214	23	100	100	NUM
fnp-3025	1214	24	years	year	NOUN
fnp-3025	1214	25	.	.	PUNCT
fnp-3025	1215	1	j	j	PROPN
fnp-3025	1215	2	neuropathol	neuropathol	PROPN
fnp-3025	1215	3	exp	exp	PROPN
fnp-3025	1215	4	neurol	neurol	PROPN
fnp-3025	1215	5	,	,	PUNCT
fnp-3025	1215	6	2011	2011	NUM
fnp-3025	1215	7	.	.	PUNCT
fnp-3025	1216	1	70(11	70(11	NUM
fnp-3025	1216	2	):	):	PUNCT
fnp-3025	1216	3	p.	p.	NOUN
fnp-3025	1216	4	960	960	NUM
fnp-3025	1216	5	-	-	SYM
fnp-3025	1216	6	9	9	NUM
fnp-3025	1216	7	.	.	NUM
fnp-3025	1216	8	147	147	NUM
fnp-3025	1216	9	.	.	PUNCT
fnp-3025	1217	1	grothe	grothe	PROPN
fnp-3025	1217	2	,	,	PUNCT
fnp-3025	1217	3	m.j	m.j	PROPN
fnp-3025	1217	4	.	.	PROPN
fnp-3025	1217	5	,	,	PUNCT
fnp-3025	1217	6	et	et	PROPN
fnp-3025	1217	7	al	al	PROPN
fnp-3025	1217	8	.	.	PROPN
fnp-3025	1217	9	,	,	PUNCT
fnp-3025	1217	10	in	in	ADP
fnp-3025	1217	11	vivo	vivo	ADJ
fnp-3025	1217	12	staging	staging	NOUN
fnp-3025	1217	13	of	of	ADP
fnp-3025	1217	14	regional	regional	ADJ
fnp-3025	1217	15	amyloid	amyloid	NOUN
fnp-3025	1217	16	deposition	deposition	NOUN
fnp-3025	1217	17	.	.	PUNCT
fnp-3025	1218	1	neurology	neurology	NOUN
fnp-3025	1218	2	,	,	PUNCT
fnp-3025	1218	3	2017	2017	NUM
fnp-3025	1218	4	.	.	PUNCT
fnp-3025	1219	1	89(20	89(20	NUM
fnp-3025	1219	2	):	):	PUNCT
fnp-3025	1219	3	p.	p.	NOUN
fnp-3025	1219	4	2031	2031	NUM
fnp-3025	1219	5	-	-	SYM
fnp-3025	1219	6	2038	2038	NUM
fnp-3025	1219	7	.	.	PUNCT
fnp-3025	1220	1	148	148	NUM
fnp-3025	1220	2	.	.	PUNCT
fnp-3025	1220	3	ogomori	ogomori	PROPN
fnp-3025	1220	4	,	,	PUNCT
fnp-3025	1220	5	k.	k.	PROPN
fnp-3025	1220	6	,	,	PUNCT
fnp-3025	1220	7	et	et	PROPN
fnp-3025	1220	8	al	al	PROPN
fnp-3025	1220	9	.	.	PROPN
fnp-3025	1220	10	,	,	PUNCT
fnp-3025	1220	11	beta	beta	NOUN
fnp-3025	1220	12	-	-	PUNCT
fnp-3025	1220	13	protein	protein	NOUN
fnp-3025	1220	14	amyloid	amyloid	NOUN
fnp-3025	1220	15	is	be	AUX
fnp-3025	1220	16	widely	widely	ADV
fnp-3025	1220	17	distributed	distribute	VERB
fnp-3025	1220	18	in	in	ADP
fnp-3025	1220	19	the	the	DET
fnp-3025	1220	20	central	central	ADJ
fnp-3025	1220	21	nervous	nervous	ADJ
fnp-3025	1220	22	system	system	NOUN
fnp-3025	1220	23	of	of	ADP
fnp-3025	1220	24	patients	patient	NOUN
fnp-3025	1220	25	with	with	ADP
fnp-3025	1220	26	alzheimer	alzheimer	PROPN
fnp-3025	1220	27	’s	’s	PART
fnp-3025	1220	28	disease	disease	NOUN
fnp-3025	1220	29	.	.	PUNCT
fnp-3025	1221	1	am	be	AUX
fnp-3025	1221	2	j	j	PROPN
fnp-3025	1221	3	pathol	pathol	NOUN
fnp-3025	1221	4	,	,	PUNCT
fnp-3025	1221	5	1989	1989	NUM
fnp-3025	1221	6	.	.	PUNCT
fnp-3025	1222	1	134(2	134(2	NUM
fnp-3025	1222	2	):	):	PUNCT
fnp-3025	1222	3	p.	p.	NOUN
fnp-3025	1222	4	243	243	NUM
fnp-3025	1222	5	-	-	SYM
fnp-3025	1222	6	51	51	NUM
fnp-3025	1222	7	.	.	NOUN
fnp-3025	1222	8	149	149	NUM
fnp-3025	1222	9	.	.	PUNCT
fnp-3025	1223	1	klunk	klunk	PROPN
fnp-3025	1223	2	,	,	PUNCT
fnp-3025	1223	3	w.e	w.e	PROPN
fnp-3025	1223	4	.	.	PROPN
fnp-3025	1223	5	,	,	PUNCT
fnp-3025	1223	6	et	et	PROPN
fnp-3025	1223	7	al	al	PROPN
fnp-3025	1223	8	.	.	PROPN
fnp-3025	1223	9	,	,	PUNCT
fnp-3025	1223	10	imaging	image	VERB
fnp-3025	1223	11	brain	brain	NOUN
fnp-3025	1223	12	amyloid	amyloid	NOUN
fnp-3025	1223	13	in	in	ADP
fnp-3025	1223	14	alzheimer	alzheimer	PROPN
fnp-3025	1223	15	’s	’s	PART
fnp-3025	1223	16	disease	disease	NOUN
fnp-3025	1223	17	with	with	ADP
fnp-3025	1223	18	pittsburgh	pittsburgh	PROPN
fnp-3025	1223	19	compound	compound	PROPN
fnp-3025	1223	20	-	-	PUNCT
fnp-3025	1223	21	b.	b.	PROPN
fnp-3025	1223	22	ann	ann	PROPN
fnp-3025	1223	23	neurol	neurol	PROPN
fnp-3025	1223	24	,	,	PUNCT
fnp-3025	1223	25	2004	2004	NUM
fnp-3025	1223	26	.	.	PUNCT
fnp-3025	1224	1	55(3	55(3	NUM
fnp-3025	1224	2	):	):	PUNCT
fnp-3025	1224	3	p.	p.	NOUN
fnp-3025	1224	4	306	306	NUM
fnp-3025	1224	5	-	-	SYM
fnp-3025	1224	6	19	19	NUM
fnp-3025	1224	7	.	.	NOUN
fnp-3025	1224	8	150	150	NUM
fnp-3025	1224	9	.	.	PUNCT
fnp-3025	1225	1	shoghi	shoghi	NOUN
fnp-3025	1225	2	-	-	PUNCT
fnp-3025	1225	3	jadid	jadid	PROPN
fnp-3025	1225	4	,	,	PUNCT
fnp-3025	1225	5	k.	k.	PROPN
fnp-3025	1225	6	,	,	PUNCT
fnp-3025	1225	7	et	et	PROPN
fnp-3025	1225	8	al	al	PROPN
fnp-3025	1225	9	.	.	PROPN
fnp-3025	1225	10	,	,	PUNCT
fnp-3025	1225	11	localization	localization	NOUN
fnp-3025	1225	12	of	of	ADP
fnp-3025	1225	13	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1225	14	tangles	tangle	NOUN
fnp-3025	1225	15	and	and	CCONJ
fnp-3025	1225	16	beta	beta	NOUN
fnp-3025	1225	17	-	-	PUNCT
fnp-3025	1225	18	amyloid	amyloid	NOUN
fnp-3025	1225	19	plaques	plaque	NOUN
fnp-3025	1225	20	in	in	ADP
fnp-3025	1225	21	the	the	DET
fnp-3025	1225	22	brains	brain	NOUN
fnp-3025	1225	23	of	of	ADP
fnp-3025	1225	24	living	live	VERB
fnp-3025	1225	25	patients	patient	NOUN
fnp-3025	1225	26	with	with	ADP
fnp-3025	1225	27	alzheimer	alzheimer	PROPN
fnp-3025	1225	28	disease	disease	PROPN
fnp-3025	1225	29	.	.	PUNCT
fnp-3025	1226	1	am	be	AUX
fnp-3025	1226	2	j	j	PROPN
fnp-3025	1226	3	geriatr	geriatr	ADJ
fnp-3025	1226	4	psychiatry	psychiatry	NOUN
fnp-3025	1226	5	,	,	PUNCT
fnp-3025	1226	6	2002	2002	NUM
fnp-3025	1226	7	.	.	PUNCT
fnp-3025	1227	1	10(1	10(1	NUM
fnp-3025	1227	2	):	):	PUNCT
fnp-3025	1227	3	p.	p.	NOUN
fnp-3025	1227	4	24	24	NUM
fnp-3025	1227	5	-	-	SYM
fnp-3025	1227	6	35	35	NUM
fnp-3025	1227	7	.	.	PUNCT
fnp-3025	1228	1	151	151	NUM
fnp-3025	1228	2	.	.	PUNCT
fnp-3025	1228	3	barrio	barrio	PROPN
fnp-3025	1228	4	,	,	PUNCT
fnp-3025	1228	5	j.r	j.r	PROPN
fnp-3025	1228	6	.	.	PROPN
fnp-3025	1228	7	,	,	PUNCT
fnp-3025	1228	8	et	et	PROPN
fnp-3025	1228	9	al	al	PROPN
fnp-3025	1228	10	.	.	PROPN
fnp-3025	1228	11	,	,	PUNCT
fnp-3025	1228	12	in	in	ADP
fnp-3025	1228	13	vivo	vivo	ADJ
fnp-3025	1228	14	characterization	characterization	NOUN
fnp-3025	1228	15	of	of	ADP
fnp-3025	1228	16	chronic	chronic	ADJ
fnp-3025	1228	17	traumatic	traumatic	ADJ
fnp-3025	1228	18	encephalopathy	encephalopathy	NOUN
fnp-3025	1228	19	using	use	VERB
fnp-3025	1228	20	[	[	X
fnp-3025	1228	21	f-18]fddnp	f-18]fddnp	ADJ
fnp-3025	1228	22	pet	pet	ADJ
fnp-3025	1228	23	brain	brain	NOUN
fnp-3025	1228	24	imaging	imaging	NOUN
fnp-3025	1228	25	.	.	PUNCT
fnp-3025	1229	1	proc	proc	PROPN
fnp-3025	1229	2	natl	natl	PROPN
fnp-3025	1229	3	acad	acad	PROPN
fnp-3025	1229	4	sci	sci	PROPN
fnp-3025	1229	5	u	u	PROPN
fnp-3025	1229	6	s	s	PROPN
fnp-3025	1229	7	a	a	PRON
fnp-3025	1229	8	,	,	PUNCT
fnp-3025	1229	9	2015	2015	NUM
fnp-3025	1229	10	.	.	PUNCT
fnp-3025	1230	1	112(16	112(16	NUM
fnp-3025	1230	2	):	):	PUNCT
fnp-3025	1230	3	p.	p.	PROPN
fnp-3025	1230	4	e2039	e2039	PROPN
fnp-3025	1230	5	-	-	PUNCT
fnp-3025	1230	6	47	47	NUM
fnp-3025	1230	7	.	.	PUNCT
fnp-3025	1231	1	152	152	NUM
fnp-3025	1231	2	.	.	PUNCT
fnp-3025	1232	1	kepe	kepe	PROPN
fnp-3025	1232	2	,	,	PUNCT
fnp-3025	1232	3	v.	v.	ADV
fnp-3025	1232	4	,	,	PUNCT
fnp-3025	1232	5	et	et	PROPN
fnp-3025	1232	6	al	al	PROPN
fnp-3025	1232	7	.	.	PROPN
fnp-3025	1232	8	,	,	PUNCT
fnp-3025	1232	9	pet	pet	ADJ
fnp-3025	1232	10	imaging	imaging	NOUN
fnp-3025	1232	11	of	of	ADP
fnp-3025	1232	12	neuropathology	neuropathology	NOUN
fnp-3025	1232	13	in	in	ADP
fnp-3025	1232	14	tauopathies	tauopathie	NOUN
fnp-3025	1232	15	:	:	PUNCT
fnp-3025	1232	16	progressive	progressive	ADJ
fnp-3025	1232	17	supranuclear	supranuclear	ADJ
fnp-3025	1232	18	palsy	palsy	ADJ
fnp-3025	1232	19	.	.	PUNCT
fnp-3025	1233	1	j	j	PROPN
fnp-3025	1233	2	alzheimers	alzheimers	PROPN
fnp-3025	1233	3	dis	dis	PROPN
fnp-3025	1233	4	,	,	PUNCT
fnp-3025	1233	5	2013	2013	NUM
fnp-3025	1233	6	.	.	PUNCT
fnp-3025	1234	1	36(1	36(1	NUM
fnp-3025	1234	2	):	):	PUNCT
fnp-3025	1234	3	p.	p.	NOUN
fnp-3025	1234	4	145	145	NUM
fnp-3025	1234	5	-	-	SYM
fnp-3025	1234	6	53	53	NUM
fnp-3025	1234	7	.	.	NUM
fnp-3025	1234	8	153	153	NUM
fnp-3025	1234	9	.	.	PUNCT
fnp-3025	1234	10	shin	shin	PROPN
fnp-3025	1234	11	,	,	PUNCT
fnp-3025	1234	12	j.	j.	PROPN
fnp-3025	1234	13	,	,	PUNCT
fnp-3025	1234	14	et	et	PROPN
fnp-3025	1234	15	al	al	PROPN
fnp-3025	1234	16	.	.	PROPN
fnp-3025	1234	17	,	,	PUNCT
fnp-3025	1234	18	the	the	DET
fnp-3025	1234	19	merits	merit	NOUN
fnp-3025	1234	20	of	of	ADP
fnp-3025	1234	21	fddnp	fddnp	ADJ
fnp-3025	1234	22	-	-	PUNCT
fnp-3025	1234	23	pet	pet	NOUN
fnp-3025	1234	24	imaging	imaging	NOUN
fnp-3025	1234	25	in	in	ADP
fnp-3025	1234	26	alzheimer	alzheimer	PROPN
fnp-3025	1234	27	’s	’s	PART
fnp-3025	1234	28	disease	disease	NOUN
fnp-3025	1234	29	.	.	PUNCT
fnp-3025	1235	1	j	j	PROPN
fnp-3025	1235	2	alzheimers	alzheimers	PROPN
fnp-3025	1235	3	dis	dis	PROPN
fnp-3025	1235	4	,	,	PUNCT
fnp-3025	1235	5	2011	2011	NUM
fnp-3025	1235	6	.	.	PUNCT
fnp-3025	1236	1	26	26	NUM
fnp-3025	1236	2	suppl	suppl	ADJ
fnp-3025	1236	3	3	3	NUM
fnp-3025	1236	4	:	:	PUNCT
fnp-3025	1236	5	p.	p.	NOUN
fnp-3025	1236	6	135	135	NUM
fnp-3025	1236	7	-	-	SYM
fnp-3025	1236	8	45	45	NUM
fnp-3025	1236	9	.	.	PUNCT
fnp-3025	1237	1	154	154	NUM
fnp-3025	1237	2	.	.	PUNCT
fnp-3025	1238	1	mathis	mathis	PROPN
fnp-3025	1238	2	,	,	PUNCT
fnp-3025	1238	3	c.a	c.a	PROPN
fnp-3025	1238	4	.	.	PROPN
fnp-3025	1238	5	,	,	PUNCT
fnp-3025	1238	6	et	et	PROPN
fnp-3025	1238	7	al	al	PROPN
fnp-3025	1238	8	.	.	PROPN
fnp-3025	1238	9	,	,	PUNCT
fnp-3025	1238	10	small	small	ADJ
fnp-3025	1238	11	-	-	PUNCT
fnp-3025	1238	12	molecule	molecule	NOUN
fnp-3025	1238	13	pet	pet	ADJ
fnp-3025	1238	14	tracers	tracer	NOUN
fnp-3025	1238	15	for	for	ADP
fnp-3025	1238	16	imaging	imaging	NOUN
fnp-3025	1238	17	proteinopathies	proteinopathie	NOUN
fnp-3025	1238	18	.	.	PUNCT
fnp-3025	1239	1	semin	semin	PROPN
fnp-3025	1239	2	nucl	nucl	PROPN
fnp-3025	1239	3	med	med	PROPN
fnp-3025	1239	4	,	,	PUNCT
fnp-3025	1239	5	2017	2017	NUM
fnp-3025	1239	6	.	.	PUNCT
fnp-3025	1240	1	47(5	47(5	NOUN
fnp-3025	1240	2	):	):	PUNCT
fnp-3025	1241	1	p.	p.	NOUN
fnp-3025	1241	2	553	553	NUM
fnp-3025	1241	3	-	-	SYM
fnp-3025	1241	4	575	575	NUM
fnp-3025	1241	5	.	.	PUNCT
fnp-3025	1242	1	155	155	NUM
fnp-3025	1242	2	.	.	PUNCT
fnp-3025	1242	3	clark	clark	PROPN
fnp-3025	1242	4	,	,	PUNCT
fnp-3025	1242	5	c.m	c.m	PROPN
fnp-3025	1242	6	.	.	PROPN
fnp-3025	1242	7	,	,	PUNCT
fnp-3025	1242	8	et	et	PROPN
fnp-3025	1242	9	al	al	PROPN
fnp-3025	1242	10	.	.	PROPN
fnp-3025	1242	11	,	,	PUNCT
fnp-3025	1242	12	use	use	NOUN
fnp-3025	1242	13	of	of	ADP
fnp-3025	1242	14	florbetapir	florbetapir	NOUN
fnp-3025	1242	15	-	-	PUNCT
fnp-3025	1242	16	pet	pet	NOUN
fnp-3025	1242	17	for	for	ADP
fnp-3025	1242	18	imaging	image	VERB
fnp-3025	1242	19	beta	beta	NOUN
fnp-3025	1242	20	-	-	PUNCT
fnp-3025	1242	21	amyloid	amyloid	NOUN
fnp-3025	1242	22	pathology	pathology	NOUN
fnp-3025	1242	23	.	.	PUNCT
fnp-3025	1243	1	jama	jama	PROPN
fnp-3025	1243	2	,	,	PUNCT
fnp-3025	1243	3	2011	2011	NUM
fnp-3025	1243	4	.	.	PUNCT
fnp-3025	1244	1	305(3	305(3	NUM
fnp-3025	1244	2	):	):	PUNCT
fnp-3025	1244	3	p.	p.	NOUN
fnp-3025	1244	4	275	275	NUM
fnp-3025	1244	5	-	-	SYM
fnp-3025	1244	6	83	83	NUM
fnp-3025	1244	7	.	.	PUNCT
fnp-3025	1244	8	156	156	NUM
fnp-3025	1244	9	.	.	PUNCT
fnp-3025	1245	1	wong	wong	PROPN
fnp-3025	1245	2	,	,	PUNCT
fnp-3025	1245	3	d.f	d.f	PROPN
fnp-3025	1245	4	.	.	PROPN
fnp-3025	1245	5	,	,	PUNCT
fnp-3025	1245	6	et	et	PROPN
fnp-3025	1245	7	al	al	PROPN
fnp-3025	1245	8	.	.	PROPN
fnp-3025	1245	9	,	,	PUNCT
fnp-3025	1245	10	in	in	ADP
fnp-3025	1245	11	vivo	vivo	ADJ
fnp-3025	1245	12	imaging	imaging	NOUN
fnp-3025	1245	13	of	of	ADP
fnp-3025	1245	14	amyloid	amyloid	NOUN
fnp-3025	1245	15	deposition	deposition	NOUN
fnp-3025	1245	16	in	in	ADP
fnp-3025	1245	17	alzheimer	alzheimer	PROPN
fnp-3025	1245	18	disease	disease	NOUN
fnp-3025	1245	19	using	use	VERB
fnp-3025	1245	20	the	the	DET
fnp-3025	1245	21	radioligand	radioligand	NOUN
fnp-3025	1245	22	18f	18f	NOUN
fnp-3025	1245	23	-	-	PUNCT
fnp-3025	1245	24	av-45	av-45	CCONJ
fnp-3025	1245	25	(	(	PUNCT
fnp-3025	1245	26	florbetapir	florbetapir	NOUN
fnp-3025	1245	27	[	[	X
fnp-3025	1245	28	corrected	correct	VERB
fnp-3025	1245	29	]	]	X
fnp-3025	1245	30	f	f	PROPN
fnp-3025	1245	31	18	18	NUM
fnp-3025	1245	32	)	)	PUNCT
fnp-3025	1245	33	.	.	PUNCT
fnp-3025	1246	1	j	j	PROPN
fnp-3025	1246	2	nucl	nucl	PROPN
fnp-3025	1246	3	med	med	PROPN
fnp-3025	1246	4	,	,	PUNCT
fnp-3025	1246	5	2010	2010	NUM
fnp-3025	1246	6	.	.	PUNCT
fnp-3025	1247	1	51(6	51(6	NUM
fnp-3025	1247	2	):	):	PUNCT
fnp-3025	1247	3	p.	p.	NOUN
fnp-3025	1247	4	913	913	NUM
fnp-3025	1247	5	-	-	SYM
fnp-3025	1247	6	20	20	NUM
fnp-3025	1247	7	.	.	PUNCT
fnp-3025	1248	1	157	157	NUM
fnp-3025	1248	2	.	.	PUNCT
fnp-3025	1249	1	sabri	sabri	NOUN
fnp-3025	1249	2	,	,	PUNCT
fnp-3025	1249	3	o.	o.	PROPN
fnp-3025	1249	4	,	,	PUNCT
fnp-3025	1249	5	et	et	PROPN
fnp-3025	1249	6	al	al	PROPN
fnp-3025	1249	7	.	.	PROPN
fnp-3025	1249	8	,	,	PUNCT
fnp-3025	1249	9	florbetaben	florbetaben	PROPN
fnp-3025	1249	10	pet	pet	PROPN
fnp-3025	1249	11	imaging	imaging	NOUN
fnp-3025	1249	12	to	to	PART
fnp-3025	1249	13	detect	detect	VERB
fnp-3025	1249	14	amyloid	amyloid	NOUN
fnp-3025	1249	15	beta	beta	NOUN
fnp-3025	1249	16	plaques	plaque	NOUN
fnp-3025	1249	17	in	in	ADP
fnp-3025	1249	18	alzheimer	alzheimer	PROPN
fnp-3025	1249	19	’s	’s	PART
fnp-3025	1249	20	disease	disease	NOUN
fnp-3025	1249	21	:	:	PUNCT
fnp-3025	1249	22	phase	phase	NOUN
fnp-3025	1249	23	3	3	NUM
fnp-3025	1249	24	study	study	NOUN
fnp-3025	1249	25	.	.	PUNCT
fnp-3025	1250	1	alzheimers	alzheimers	PROPN
fnp-3025	1250	2	dement	dement	PROPN
fnp-3025	1250	3	,	,	PUNCT
fnp-3025	1250	4	2015	2015	NUM
fnp-3025	1250	5	.	.	PUNCT
fnp-3025	1251	1	11(8	11(8	NUM
fnp-3025	1251	2	):	):	PUNCT
fnp-3025	1252	1	p.	p.	NOUN
fnp-3025	1252	2	964	964	NUM
fnp-3025	1252	3	-	-	SYM
fnp-3025	1252	4	74	74	NUM
fnp-3025	1252	5	.	.	PUNCT
fnp-3025	1252	6	158	158	NUM
fnp-3025	1252	7	.	.	PUNCT
fnp-3025	1253	1	vandenberghe	vandenberghe	PROPN
fnp-3025	1253	2	,	,	PUNCT
fnp-3025	1253	3	r.	r.	PROPN
fnp-3025	1253	4	,	,	PUNCT
fnp-3025	1253	5	et	et	PROPN
fnp-3025	1253	6	al	al	PROPN
fnp-3025	1253	7	.	.	PROPN
fnp-3025	1253	8	,	,	PUNCT
fnp-3025	1253	9	18f	18f	NUM
fnp-3025	1253	10	-	-	PUNCT
fnp-3025	1253	11	flutemetamol	flutemetamol	PROPN
fnp-3025	1253	12	amyloid	amyloid	NOUN
fnp-3025	1253	13	imaging	imaging	NOUN
fnp-3025	1253	14	in	in	ADP
fnp-3025	1253	15	alzheimer	alzheimer	PROPN
fnp-3025	1253	16	disease	disease	NOUN
fnp-3025	1253	17	and	and	CCONJ
fnp-3025	1253	18	mild	mild	ADJ
fnp-3025	1253	19	cognitive	cognitive	ADJ
fnp-3025	1253	20	impairment	impairment	NOUN
fnp-3025	1253	21	:	:	PUNCT
fnp-3025	1253	22	a	a	DET
fnp-3025	1253	23	phase	phase	NOUN
fnp-3025	1253	24	2	2	NUM
fnp-3025	1253	25	trial	trial	NOUN
fnp-3025	1253	26	.	.	PUNCT
fnp-3025	1254	1	ann	ann	PROPN
fnp-3025	1254	2	neurol	neurol	PROPN
fnp-3025	1254	3	,	,	PUNCT
fnp-3025	1254	4	2010	2010	NUM
fnp-3025	1254	5	.	.	PUNCT
fnp-3025	1255	1	68(3	68(3	X
fnp-3025	1255	2	):	):	PUNCT
fnp-3025	1255	3	p.	p.	NOUN
fnp-3025	1255	4	319	319	NUM
fnp-3025	1255	5	-	-	SYM
fnp-3025	1255	6	29	29	NUM
fnp-3025	1255	7	.	.	PUNCT
fnp-3025	1256	1	159	159	NUM
fnp-3025	1256	2	.	.	PUNCT
fnp-3025	1257	1	ikonomovic	ikonomovic	ADJ
fnp-3025	1257	2	,	,	PUNCT
fnp-3025	1257	3	m.d	m.d	PROPN
fnp-3025	1257	4	.	.	PROPN
fnp-3025	1257	5	,	,	PUNCT
fnp-3025	1257	6	et	et	PROPN
fnp-3025	1257	7	al	al	PROPN
fnp-3025	1257	8	.	.	PROPN
fnp-3025	1257	9	,	,	PUNCT
fnp-3025	1257	10	post	post	ADJ
fnp-3025	1257	11	-	-	ADJ
fnp-3025	1257	12	mortem	mortem	ADJ
fnp-3025	1257	13	histopathology	histopathology	NOUN
fnp-3025	1257	14	underlying	underlie	VERB
fnp-3025	1257	15	beta	beta	NOUN
fnp-3025	1257	16	-	-	PUNCT
fnp-3025	1257	17	amyloid	amyloid	NOUN
fnp-3025	1257	18	pet	pet	ADJ
fnp-3025	1257	19	imaging	imaging	NOUN
fnp-3025	1257	20	following	follow	VERB
fnp-3025	1257	21	flutemetamol	flutemetamol	PROPN
fnp-3025	1257	22	f	f	PROPN
fnp-3025	1257	23	18	18	NUM
fnp-3025	1257	24	injection	injection	NOUN
fnp-3025	1257	25	.	.	PUNCT
fnp-3025	1258	1	acta	acta	PROPN
fnp-3025	1258	2	neuropathol	neuropathol	PROPN
fnp-3025	1258	3	commun	commun	PROPN
fnp-3025	1258	4	,	,	PUNCT
fnp-3025	1258	5	2016	2016	NUM
fnp-3025	1258	6	.	.	PUNCT
fnp-3025	1259	1	4(1	4(1	NOUN
fnp-3025	1259	2	):	):	PUNCT
fnp-3025	1260	1	p.	p.	NOUN
fnp-3025	1260	2	130	130	NUM
fnp-3025	1260	3	.	.	PUNCT
fnp-3025	1260	4	160	160	NUM
fnp-3025	1260	5	.	.	PUNCT
fnp-3025	1260	6	salloway	salloway	NOUN
fnp-3025	1260	7	,	,	PUNCT
fnp-3025	1260	8	s.	s.	PROPN
fnp-3025	1260	9	,	,	PUNCT
fnp-3025	1260	10	et	et	PROPN
fnp-3025	1260	11	al	al	PROPN
fnp-3025	1260	12	.	.	PROPN
fnp-3025	1260	13	,	,	PUNCT
fnp-3025	1260	14	performance	performance	NOUN
fnp-3025	1260	15	of	of	ADP
fnp-3025	1260	16	[	[	X
fnp-3025	1260	17	(	(	PUNCT
fnp-3025	1260	18	18)f]flutemetamol	18)f]flutemetamol	NUM
fnp-3025	1260	19	amyloid	amyloid	NOUN
fnp-3025	1260	20	imaging	imaging	NOUN
fnp-3025	1260	21	against	against	ADP
fnp-3025	1260	22	the	the	DET
fnp-3025	1260	23	neuritic	neuritic	ADJ
fnp-3025	1260	24	plaque	plaque	NOUN
fnp-3025	1260	25	component	component	NOUN
fnp-3025	1260	26	of	of	ADP
fnp-3025	1260	27	cerad	cerad	NOUN
fnp-3025	1260	28	and	and	CCONJ
fnp-3025	1260	29	the	the	DET
fnp-3025	1260	30	current	current	ADJ
fnp-3025	1260	31	(	(	PUNCT
fnp-3025	1260	32	2012	2012	NUM
fnp-3025	1260	33	)	)	PUNCT
fnp-3025	1260	34	nia	nia	ADJ
fnp-3025	1260	35	-	-	PUNCT
fnp-3025	1260	36	aa	aa	NOUN
fnp-3025	1260	37	recommendations	recommendation	NOUN
fnp-3025	1260	38	for	for	ADP
fnp-3025	1260	39	the	the	DET
fnp-3025	1260	40	neuropathologic	neuropathologic	ADJ
fnp-3025	1260	41	diagnosis	diagnosis	NOUN
fnp-3025	1260	42	of	of	ADP
fnp-3025	1260	43	alzheimer	alzheimer	PROPN
fnp-3025	1260	44	’s	’s	PART
fnp-3025	1260	45	disease	disease	NOUN
fnp-3025	1260	46	.	.	PUNCT
fnp-3025	1261	1	alzheimers	alzheimers	PROPN
fnp-3025	1261	2	dement	dement	PROPN
fnp-3025	1261	3	(	(	PUNCT
fnp-3025	1261	4	amst	amst	PROPN
fnp-3025	1261	5	)	)	PUNCT
fnp-3025	1261	6	,	,	PUNCT
fnp-3025	1261	7	2017	2017	NUM
fnp-3025	1261	8	.	.	PUNCT
fnp-3025	1262	1	9	9	NUM
fnp-3025	1262	2	:	:	PUNCT
fnp-3025	1262	3	p.	p.	NOUN
fnp-3025	1262	4	25	25	NUM
fnp-3025	1262	5	-	-	SYM
fnp-3025	1262	6	34	34	NUM
fnp-3025	1262	7	.	.	NOUN
fnp-3025	1262	8	161	161	NUM
fnp-3025	1262	9	.	.	PUNCT
fnp-3025	1263	1	thal	thal	PROPN
fnp-3025	1263	2	,	,	PUNCT
fnp-3025	1263	3	d.r	d.r	PROPN
fnp-3025	1263	4	.	.	PROPN
fnp-3025	1263	5	,	,	PUNCT
fnp-3025	1263	6	et	et	PROPN
fnp-3025	1263	7	al	al	PROPN
fnp-3025	1263	8	.	.	PROPN
fnp-3025	1263	9	,	,	PUNCT
fnp-3025	1263	10	different	different	ADJ
fnp-3025	1263	11	aspects	aspect	NOUN
fnp-3025	1263	12	of	of	ADP
fnp-3025	1263	13	alzheimer	alzheimer	PROPN
fnp-3025	1263	14	’s	’s	PART
fnp-3025	1263	15	disease	disease	NOUN
fnp-3025	1263	16	-	-	PUNCT
fnp-3025	1263	17	related	relate	VERB
fnp-3025	1263	18	amyloid	amyloid	NOUN
fnp-3025	1263	19	beta	beta	NOUN
fnp-3025	1263	20	-	-	PUNCT
fnp-3025	1263	21	peptide	peptide	NOUN
fnp-3025	1263	22	pathology	pathology	NOUN
fnp-3025	1263	23	and	and	CCONJ
fnp-3025	1263	24	their	their	PRON
fnp-3025	1263	25	relationship	relationship	NOUN
fnp-3025	1263	26	to	to	PART
fnp-3025	1263	27	amyloid	amyloid	VERB
fnp-3025	1263	28	positron	positron	NOUN
fnp-3025	1263	29	emission	emission	NOUN
fnp-3025	1263	30	tomography	tomography	NOUN
fnp-3025	1263	31	imaging	imaging	NOUN
fnp-3025	1263	32	and	and	CCONJ
fnp-3025	1263	33	dementia	dementia	NOUN
fnp-3025	1263	34	.	.	PUNCT
fnp-3025	1264	1	acta	acta	PROPN
fnp-3025	1264	2	neuropathol	neuropathol	PROPN
fnp-3025	1264	3	commun	commun	PROPN
fnp-3025	1264	4	,	,	PUNCT
fnp-3025	1264	5	2019	2019	NUM
fnp-3025	1264	6	.	.	PUNCT
fnp-3025	1265	1	7(1	7(1	NUM
fnp-3025	1265	2	):	):	PUNCT
fnp-3025	1265	3	p.	p.	NOUN
fnp-3025	1265	4	178	178	NUM
fnp-3025	1265	5	.	.	PUNCT
fnp-3025	1266	1	162	162	NUM
fnp-3025	1266	2	.	.	PUNCT
fnp-3025	1267	1	diner	diner	PROPN
fnp-3025	1267	2	,	,	PUNCT
fnp-3025	1267	3	i.	i.	PROPN
fnp-3025	1267	4	,	,	PUNCT
fnp-3025	1267	5	et	et	PROPN
fnp-3025	1267	6	al	al	PROPN
fnp-3025	1267	7	.	.	PROPN
fnp-3025	1267	8	,	,	PUNCT
fnp-3025	1267	9	generation	generation	NOUN
fnp-3025	1267	10	of	of	ADP
fnp-3025	1267	11	clickable	clickable	ADJ
fnp-3025	1267	12	pittsburgh	pittsburgh	PROPN
fnp-3025	1267	13	compound	compound	PROPN
fnp-3025	1267	14	b	b	PROPN
fnp-3025	1267	15	for	for	ADP
fnp-3025	1267	16	the	the	DET
fnp-3025	1267	17	detection	detection	NOUN
fnp-3025	1267	18	and	and	CCONJ
fnp-3025	1267	19	capture	capture	NOUN
fnp-3025	1267	20	of	of	ADP
fnp-3025	1267	21	beta	beta	NOUN
fnp-3025	1267	22	-	-	PUNCT
fnp-3025	1267	23	amyloid	amyloid	NOUN
fnp-3025	1267	24	in	in	ADP
fnp-3025	1267	25	alzheimer	alzheimer	PROPN
fnp-3025	1267	26	’s	’s	PART
fnp-3025	1267	27	disease	disease	NOUN
fnp-3025	1267	28	brain	brain	NOUN
fnp-3025	1267	29	.	.	PUNCT
fnp-3025	1268	1	bioconjug	bioconjug	NOUN
fnp-3025	1268	2	chem	chem	NOUN
fnp-3025	1268	3	,	,	PUNCT
fnp-3025	1268	4	2017	2017	NUM
fnp-3025	1268	5	.	.	PUNCT
fnp-3025	1269	1	28(10	28(10	NUM
fnp-3025	1269	2	):	):	PUNCT
fnp-3025	1269	3	p.	p.	NOUN
fnp-3025	1269	4	2627	2627	NUM
fnp-3025	1269	5	-	-	SYM
fnp-3025	1269	6	2637	2637	NUM
fnp-3025	1269	7	.	.	PUNCT
fnp-3025	1270	1	163	163	NUM
fnp-3025	1270	2	.	.	PUNCT
fnp-3025	1271	1	rosen	rosen	PROPN
fnp-3025	1271	2	,	,	PUNCT
fnp-3025	1271	3	r.f	r.f	PROPN
fnp-3025	1271	4	.	.	PROPN
fnp-3025	1271	5	,	,	PUNCT
fnp-3025	1271	6	et	et	PROPN
fnp-3025	1271	7	al	al	PROPN
fnp-3025	1271	8	.	.	PROPN
fnp-3025	1271	9	,	,	PUNCT
fnp-3025	1271	10	comparative	comparative	ADJ
fnp-3025	1271	11	pathobiology	pathobiology	NOUN
fnp-3025	1271	12	of	of	ADP
fnp-3025	1271	13	beta	beta	NOUN
fnp-3025	1271	14	-	-	PUNCT
fnp-3025	1271	15	amyloid	amyloid	NOUN
fnp-3025	1271	16	and	and	CCONJ
fnp-3025	1271	17	the	the	DET
fnp-3025	1271	18	unique	unique	ADJ
fnp-3025	1271	19	susceptibility	susceptibility	NOUN
fnp-3025	1271	20	of	of	ADP
fnp-3025	1271	21	humans	human	NOUN
fnp-3025	1271	22	to	to	ADP
fnp-3025	1271	23	alzheimer	alzheimer	PROPN
fnp-3025	1271	24	’s	’s	PART
fnp-3025	1271	25	disease	disease	NOUN
fnp-3025	1271	26	.	.	PUNCT
fnp-3025	1272	1	neurobiol	neurobiol	PROPN
fnp-3025	1272	2	aging	aging	NOUN
fnp-3025	1272	3	,	,	PUNCT
fnp-3025	1272	4	2016	2016	NUM
fnp-3025	1272	5	.	.	PUNCT
fnp-3025	1273	1	44	44	NUM
fnp-3025	1273	2	:	:	PUNCT
fnp-3025	1273	3	p.	p.	NOUN
fnp-3025	1273	4	185	185	NUM
fnp-3025	1273	5	-	-	SYM
fnp-3025	1273	6	196	196	NUM
fnp-3025	1273	7	.	.	PUNCT
fnp-3025	1273	8	164	164	NUM
fnp-3025	1273	9	.	.	PUNCT
fnp-3025	1274	1	rosen	rosen	PROPN
fnp-3025	1274	2	,	,	PUNCT
fnp-3025	1274	3	r.f	r.f	PROPN
fnp-3025	1274	4	.	.	PROPN
fnp-3025	1274	5	,	,	PUNCT
fnp-3025	1274	6	et	et	PROPN
fnp-3025	1274	7	al	al	PROPN
fnp-3025	1274	8	.	.	PROPN
fnp-3025	1274	9	,	,	PUNCT
fnp-3025	1274	10	deficient	deficient	ADJ
fnp-3025	1274	11	high	high	ADJ
fnp-3025	1274	12	-	-	PUNCT
fnp-3025	1274	13	affinity	affinity	NOUN
fnp-3025	1274	14	binding	binding	NOUN
fnp-3025	1274	15	of	of	ADP
fnp-3025	1274	16	pittsburgh	pittsburgh	PROPN
fnp-3025	1274	17	compound	compound	PROPN
fnp-3025	1274	18	b	b	PROPN
fnp-3025	1274	19	in	in	ADP
fnp-3025	1274	20	a	a	DET
fnp-3025	1274	21	case	case	NOUN
fnp-3025	1274	22	of	of	ADP
fnp-3025	1274	23	alzheimer	alzheimer	PROPN
fnp-3025	1274	24	’s	’s	PART
fnp-3025	1274	25	disease	disease	NOUN
fnp-3025	1274	26	.	.	PUNCT
fnp-3025	1275	1	acta	acta	PROPN
fnp-3025	1275	2	neuropathol	neuropathol	PROPN
fnp-3025	1275	3	,	,	PUNCT
fnp-3025	1275	4	2010	2010	NUM
fnp-3025	1275	5	.	.	PUNCT
fnp-3025	1276	1	119(2	119(2	NUM
fnp-3025	1276	2	):	):	PUNCT
fnp-3025	1276	3	p.	p.	NOUN
fnp-3025	1276	4	221	221	NUM
fnp-3025	1276	5	-	-	SYM
fnp-3025	1276	6	33	33	NUM
fnp-3025	1276	7	.	.	PUNCT
fnp-3025	1276	8	165	165	NUM
fnp-3025	1276	9	.	.	X
fnp-3025	1276	10	walker	walker	PROPN
fnp-3025	1276	11	,	,	PUNCT
fnp-3025	1276	12	l.c	l.c	PROPN
fnp-3025	1276	13	.	.	PROPN
fnp-3025	1276	14	and	and	CCONJ
fnp-3025	1276	15	m.	m.	PROPN
fnp-3025	1276	16	jucker	jucker	PROPN
fnp-3025	1276	17	,	,	PUNCT
fnp-3025	1276	18	the	the	DET
fnp-3025	1276	19	exceptional	exceptional	ADJ
fnp-3025	1276	20	vulnerability	vulnerability	NOUN
fnp-3025	1276	21	of	of	ADP
fnp-3025	1276	22	humans	human	NOUN
fnp-3025	1276	23	to	to	ADP
fnp-3025	1276	24	alzheimer	alzheimer	PROPN
fnp-3025	1276	25	’s	’s	PART
fnp-3025	1276	26	disease	disease	NOUN
fnp-3025	1276	27	.	.	PUNCT
fnp-3025	1277	1	trends	trend	NOUN
fnp-3025	1277	2	mol	mol	ADP
fnp-3025	1277	3	med	med	ADJ
fnp-3025	1277	4	,	,	PUNCT
fnp-3025	1277	5	2017	2017	NUM
fnp-3025	1277	6	.	.	PUNCT
fnp-3025	1278	1	23(6	23(6	NUM
fnp-3025	1278	2	):	):	PUNCT
fnp-3025	1279	1	p.	p.	NOUN
fnp-3025	1279	2	534	534	NUM
fnp-3025	1279	3	-	-	SYM
fnp-3025	1279	4	545	545	NUM
fnp-3025	1279	5	.	.	PUNCT
fnp-3025	1279	6	166	166	NUM
fnp-3025	1279	7	.	.	PUNCT
fnp-3025	1280	1	ikeda	ikeda	PROPN
fnp-3025	1280	2	,	,	PUNCT
fnp-3025	1280	3	s.	s.	PROPN
fnp-3025	1280	4	,	,	PUNCT
fnp-3025	1280	5	d.	d.	PROPN
fnp-3025	1280	6	allsop	allsop	PROPN
fnp-3025	1280	7	,	,	PUNCT
fnp-3025	1280	8	and	and	CCONJ
fnp-3025	1280	9	g.g	g.g	PROPN
fnp-3025	1280	10	.	.	PROPN
fnp-3025	1280	11	glenner	glenner	NOUN
fnp-3025	1280	12	,	,	PUNCT
fnp-3025	1280	13	morphology	morphology	NOUN
fnp-3025	1280	14	and	and	CCONJ
fnp-3025	1280	15	distribution	distribution	NOUN
fnp-3025	1280	16	of	of	ADP
fnp-3025	1280	17	plaque	plaque	NOUN
fnp-3025	1280	18	and	and	CCONJ
fnp-3025	1280	19	related	related	ADJ
fnp-3025	1280	20	deposits	deposit	NOUN
fnp-3025	1280	21	in	in	ADP
fnp-3025	1280	22	the	the	DET
fnp-3025	1280	23	brains	brain	NOUN
fnp-3025	1280	24	of	of	ADP
fnp-3025	1280	25	alzheimer	alzheimer	PROPN
fnp-3025	1280	26	’s	’s	PART
fnp-3025	1280	27	disease	disease	NOUN
fnp-3025	1280	28	and	and	CCONJ
fnp-3025	1280	29	control	control	NOUN
fnp-3025	1280	30	cases	case	NOUN
fnp-3025	1280	31	.	.	PUNCT
fnp-3025	1281	1	an	an	DET
fnp-3025	1281	2	immunohistochemical	immunohistochemical	ADJ
fnp-3025	1281	3	study	study	NOUN
fnp-3025	1281	4	using	use	VERB
fnp-3025	1281	5	amyloid	amyloid	NOUN
fnp-3025	1281	6	beta	beta	NOUN
fnp-3025	1281	7	-	-	PUNCT
fnp-3025	1281	8	protein	protein	NOUN
fnp-3025	1281	9	antibody	antibody	NOUN
fnp-3025	1281	10	.	.	PUNCT
fnp-3025	1282	1	lab	lab	NOUN
fnp-3025	1282	2	invest	invest	PROPN
fnp-3025	1282	3	,	,	PUNCT
fnp-3025	1282	4	1989	1989	NUM
fnp-3025	1282	5	.	.	PUNCT
fnp-3025	1283	1	60(1	60(1	NUM
fnp-3025	1283	2	):	):	PUNCT
fnp-3025	1284	1	p.	p.	NOUN
fnp-3025	1284	2	113	113	NUM
fnp-3025	1284	3	-	-	SYM
fnp-3025	1284	4	22	22	NUM
fnp-3025	1284	5	.	.	PUNCT
fnp-3025	1284	6	167	167	NUM
fnp-3025	1284	7	.	.	PUNCT
fnp-3025	1285	1	ikeda	ikeda	PROPN
fnp-3025	1285	2	,	,	PUNCT
fnp-3025	1285	3	s.	s.	PROPN
fnp-3025	1285	4	,	,	PUNCT
fnp-3025	1285	5	et	et	PROPN
fnp-3025	1285	6	al	al	PROPN
fnp-3025	1285	7	.	.	PROPN
fnp-3025	1285	8	,	,	PUNCT
fnp-3025	1285	9	evidence	evidence	NOUN
fnp-3025	1285	10	of	of	ADP
fnp-3025	1285	11	amyloid	amyloid	NOUN
fnp-3025	1285	12	beta	beta	NOUN
fnp-3025	1285	13	-	-	PUNCT
fnp-3025	1285	14	protein	protein	NOUN
fnp-3025	1285	15	immunoreactive	immunoreactive	ADJ
fnp-3025	1285	16	early	early	ADJ
fnp-3025	1285	17	plaque	plaque	NOUN
fnp-3025	1285	18	lesions	lesion	NOUN
fnp-3025	1285	19	in	in	ADP
fnp-3025	1285	20	down	down	ADP
fnp-3025	1285	21	’s	’s	PART
fnp-3025	1285	22	syndrome	syndrome	NOUN
fnp-3025	1285	23	brains	brain	NOUN
fnp-3025	1285	24	.	.	PUNCT
fnp-3025	1286	1	lab	lab	NOUN
fnp-3025	1286	2	invest	invest	PROPN
fnp-3025	1286	3	,	,	PUNCT
fnp-3025	1286	4	1989	1989	NUM
fnp-3025	1286	5	.	.	PUNCT
fnp-3025	1287	1	61(1	61(1	NOUN
fnp-3025	1287	2	):	):	PUNCT
fnp-3025	1287	3	p.	p.	NOUN
fnp-3025	1287	4	133	133	NUM
fnp-3025	1287	5	-	-	SYM
fnp-3025	1287	6	7	7	NUM
fnp-3025	1287	7	.	.	NOUN
fnp-3025	1287	8	168	168	NUM
fnp-3025	1287	9	.	.	PUNCT
fnp-3025	1288	1	tagliavini	tagliavini	PROPN
fnp-3025	1288	2	,	,	PUNCT
fnp-3025	1288	3	f.	f.	PROPN
fnp-3025	1288	4	,	,	PUNCT
fnp-3025	1288	5	et	et	PROPN
fnp-3025	1288	6	al	al	PROPN
fnp-3025	1288	7	.	.	PROPN
fnp-3025	1288	8	,	,	PUNCT
fnp-3025	1288	9	preamyloid	preamyloid	ADJ
fnp-3025	1288	10	deposits	deposit	NOUN
fnp-3025	1288	11	in	in	ADP
fnp-3025	1288	12	the	the	DET
fnp-3025	1288	13	cerebral	cerebral	ADJ
fnp-3025	1288	14	cortex	cortex	NOUN
fnp-3025	1288	15	of	of	ADP
fnp-3025	1288	16	patients	patient	NOUN
fnp-3025	1288	17	with	with	ADP
fnp-3025	1288	18	alzheimer	alzheimer	PROPN
fnp-3025	1288	19	’s	’s	PART
fnp-3025	1288	20	disease	disease	NOUN
fnp-3025	1288	21	and	and	CCONJ
fnp-3025	1288	22	nondemented	nondemented	ADJ
fnp-3025	1288	23	individuals	individual	NOUN
fnp-3025	1288	24	.	.	PUNCT
fnp-3025	1289	1	neurosci	neurosci	PROPN
fnp-3025	1289	2	lett	lett	PROPN
fnp-3025	1289	3	,	,	PUNCT
fnp-3025	1289	4	1988	1988	NUM
fnp-3025	1289	5	.	.	PUNCT
fnp-3025	1290	1	93(2	93(2	NOUN
fnp-3025	1290	2	-	-	PUNCT
fnp-3025	1290	3	3	3	NUM
fnp-3025	1290	4	):	):	PUNCT
fnp-3025	1290	5	p.	p.	NOUN
fnp-3025	1290	6	191	191	NUM
fnp-3025	1290	7	-	-	SYM
fnp-3025	1290	8	6	6	NUM
fnp-3025	1290	9	.	.	NOUN
fnp-3025	1290	10	169	169	NUM
fnp-3025	1290	11	.	.	PUNCT
fnp-3025	1291	1	tagliavini	tagliavini	PROPN
fnp-3025	1291	2	,	,	PUNCT
fnp-3025	1291	3	f.	f.	PROPN
fnp-3025	1291	4	,	,	PUNCT
fnp-3025	1291	5	et	et	PROPN
fnp-3025	1291	6	al	al	PROPN
fnp-3025	1291	7	.	.	PROPN
fnp-3025	1291	8	,	,	PUNCT
fnp-3025	1291	9	cerebral	cerebral	ADJ
fnp-3025	1291	10	extracellular	extracellular	ADJ
fnp-3025	1291	11	preamyloid	preamyloid	ADJ
fnp-3025	1291	12	deposits	deposit	NOUN
fnp-3025	1291	13	in	in	ADP
fnp-3025	1291	14	alzheimer	alzheimer	PROPN
fnp-3025	1291	15	’s	’s	PART
fnp-3025	1291	16	disease	disease	NOUN
fnp-3025	1291	17	,	,	PUNCT
fnp-3025	1291	18	down	down	ADP
fnp-3025	1291	19	syndrome	syndrome	NOUN
fnp-3025	1291	20	and	and	CCONJ
fnp-3025	1291	21	nondemented	nondemente	VERB
fnp-3025	1291	22	elderly	elderly	ADJ
fnp-3025	1291	23	individuals	individual	NOUN
fnp-3025	1291	24	.	.	PUNCT
fnp-3025	1292	1	prog	prog	PROPN
fnp-3025	1292	2	clin	clin	PROPN
fnp-3025	1292	3	biol	biol	PROPN
fnp-3025	1292	4	res	re	NOUN
fnp-3025	1292	5	,	,	PUNCT
fnp-3025	1292	6	1989	1989	NUM
fnp-3025	1292	7	.	.	PUNCT
fnp-3025	1293	1	317	317	NUM
fnp-3025	1293	2	:	:	PUNCT
fnp-3025	1293	3	p.	p.	NOUN
fnp-3025	1293	4	1001	1001	NUM
fnp-3025	1293	5	-	-	SYM
fnp-3025	1293	6	5	5	NUM
fnp-3025	1293	7	.	.	NUM
fnp-3025	1293	8	170	170	NUM
fnp-3025	1293	9	.	.	PUNCT
fnp-3025	1294	1	yamaguchi	yamaguchi	PROPN
fnp-3025	1294	2	,	,	PUNCT
fnp-3025	1294	3	h.	h.	PROPN
fnp-3025	1294	4	,	,	PUNCT
fnp-3025	1294	5	et	et	PROPN
fnp-3025	1294	6	al	al	PROPN
fnp-3025	1294	7	.	.	PROPN
fnp-3025	1294	8	,	,	PUNCT
fnp-3025	1294	9	diffuse	diffuse	ADJ
fnp-3025	1294	10	type	type	NOUN
fnp-3025	1294	11	of	of	ADP
fnp-3025	1294	12	senile	senile	ADJ
fnp-3025	1294	13	plaques	plaque	NOUN
fnp-3025	1294	14	in	in	ADP
fnp-3025	1294	15	the	the	DET
fnp-3025	1294	16	brains	brain	NOUN
fnp-3025	1294	17	of	of	ADP
fnp-3025	1294	18	alzheimer	alzheimer	NOUN
fnp-3025	1294	19	-	-	PUNCT
fnp-3025	1294	20	type	type	NOUN
fnp-3025	1294	21	dementia	dementia	NOUN
fnp-3025	1294	22	.	.	PUNCT
fnp-3025	1295	1	acta	acta	PROPN
fnp-3025	1295	2	neuropathol	neuropathol	PROPN
fnp-3025	1295	3	,	,	PUNCT
fnp-3025	1295	4	1988	1988	NUM
fnp-3025	1295	5	.	.	PUNCT
fnp-3025	1296	1	77(2	77(2	X
fnp-3025	1296	2	):	):	PUNCT
fnp-3025	1296	3	p.	p.	NOUN
fnp-3025	1296	4	113	113	NUM
fnp-3025	1296	5	-	-	SYM
fnp-3025	1296	6	9	9	NUM
fnp-3025	1296	7	.	.	NOUN
fnp-3025	1296	8	171	171	NUM
fnp-3025	1296	9	.	.	PUNCT
fnp-3025	1297	1	yamaguchi	yamaguchi	PROPN
fnp-3025	1297	2	,	,	PUNCT
fnp-3025	1297	3	h.	h.	PROPN
fnp-3025	1297	4	,	,	PUNCT
fnp-3025	1297	5	et	et	PROPN
fnp-3025	1297	6	al	al	PROPN
fnp-3025	1297	7	.	.	PROPN
fnp-3025	1297	8	,	,	PUNCT
fnp-3025	1297	9	a	a	DET
fnp-3025	1297	10	variety	variety	NOUN
fnp-3025	1297	11	of	of	ADP
fnp-3025	1297	12	cerebral	cerebral	ADJ
fnp-3025	1297	13	amyloid	amyloid	NOUN
fnp-3025	1297	14	deposits	deposit	NOUN
fnp-3025	1297	15	in	in	ADP
fnp-3025	1297	16	the	the	DET
fnp-3025	1297	17	brains	brain	NOUN
fnp-3025	1297	18	of	of	ADP
fnp-3025	1297	19	the	the	DET
fnp-3025	1297	20	alzheimer	alzheimer	ADJ
fnp-3025	1297	21	-	-	PUNCT
fnp-3025	1297	22	type	type	NOUN
fnp-3025	1297	23	dementia	dementia	NOUN
fnp-3025	1297	24	demonstrated	demonstrate	VERB
fnp-3025	1297	25	by	by	ADP
fnp-3025	1297	26	beta	beta	ADJ
fnp-3025	1297	27	protein	protein	NOUN
fnp-3025	1297	28	immunostaining	immunostaining	NOUN
fnp-3025	1297	29	.	.	PUNCT
fnp-3025	1298	1	acta	acta	PROPN
fnp-3025	1298	2	neuropathol	neuropathol	PROPN
fnp-3025	1298	3	,	,	PUNCT
fnp-3025	1298	4	1988	1988	NUM
fnp-3025	1298	5	.	.	PUNCT
fnp-3025	1299	1	76(6	76(6	X
fnp-3025	1299	2	):	):	PUNCT
fnp-3025	1299	3	p.	p.	NOUN
fnp-3025	1299	4	541	541	NUM
fnp-3025	1299	5	-	-	SYM
fnp-3025	1299	6	9	9	NUM
fnp-3025	1299	7	.	.	X
fnp-3025	1300	1	172	172	NUM
fnp-3025	1300	2	.	.	PUNCT
fnp-3025	1301	1	yamaguchi	yamaguchi	PROPN
fnp-3025	1301	2	,	,	PUNCT
fnp-3025	1301	3	h.	h.	PROPN
fnp-3025	1301	4	,	,	PUNCT
fnp-3025	1301	5	et	et	PROPN
fnp-3025	1301	6	al	al	PROPN
fnp-3025	1301	7	.	.	PROPN
fnp-3025	1301	8	,	,	PUNCT
fnp-3025	1301	9	alzheimer	alzheimer	PROPN
fnp-3025	1301	10	type	type	NOUN
fnp-3025	1301	11	dementia	dementia	NOUN
fnp-3025	1301	12	:	:	PUNCT
fnp-3025	1301	13	diffuse	diffuse	ADJ
fnp-3025	1301	14	type	type	NOUN
fnp-3025	1301	15	of	of	ADP
fnp-3025	1301	16	senile	senile	ADJ
fnp-3025	1301	17	plaques	plaque	NOUN
fnp-3025	1301	18	demonstrated	demonstrate	VERB
fnp-3025	1301	19	by	by	ADP
fnp-3025	1301	20	beta	beta	ADJ
fnp-3025	1301	21	protein	protein	NOUN
fnp-3025	1301	22	immunostaining	immunostaining	NOUN
fnp-3025	1301	23	.	.	PUNCT
fnp-3025	1302	1	prog	prog	PROPN
fnp-3025	1302	2	clin	clin	PROPN
fnp-3025	1302	3	biol	biol	PROPN
fnp-3025	1302	4	res	re	NOUN
fnp-3025	1302	5	,	,	PUNCT
fnp-3025	1302	6	1989	1989	NUM
fnp-3025	1302	7	.	.	PUNCT
fnp-3025	1303	1	317	317	NUM
fnp-3025	1303	2	:	:	PUNCT
fnp-3025	1304	1	p.	p.	NOUN
fnp-3025	1304	2	467	467	NUM
fnp-3025	1304	3	-	-	SYM
fnp-3025	1304	4	74	74	NUM
fnp-3025	1304	5	.	.	PUNCT
fnp-3025	1305	1	173	173	NUM
fnp-3025	1305	2	.	.	PUNCT
fnp-3025	1306	1	armstrong	armstrong	PROPN
fnp-3025	1306	2	,	,	PUNCT
fnp-3025	1306	3	r.a	r.a	PROPN
fnp-3025	1306	4	.	.	PROPN
fnp-3025	1306	5	,	,	PUNCT
fnp-3025	1306	6	beta	beta	NOUN
fnp-3025	1306	7	-	-	PUNCT
fnp-3025	1306	8	amyloid	amyloid	NOUN
fnp-3025	1306	9	plaques	plaque	NOUN
fnp-3025	1306	10	:	:	PUNCT
fnp-3025	1306	11	stages	stage	NOUN
fnp-3025	1306	12	in	in	ADP
fnp-3025	1306	13	life	life	NOUN
fnp-3025	1306	14	history	history	NOUN
fnp-3025	1306	15	or	or	CCONJ
fnp-3025	1306	16	independent	independent	ADJ
fnp-3025	1306	17	origin	origin	NOUN
fnp-3025	1306	18	?	?	PUNCT
fnp-3025	1307	1	dement	dement	PROPN
fnp-3025	1307	2	geriatr	geriatr	PROPN
fnp-3025	1307	3	cogn	cogn	PROPN
fnp-3025	1307	4	disord	disord	NOUN
fnp-3025	1307	5	,	,	PUNCT
fnp-3025	1307	6	1998	1998	NUM
fnp-3025	1307	7	.	.	PUNCT
fnp-3025	1308	1	9(4	9(4	NUM
fnp-3025	1308	2	):	):	PUNCT
fnp-3025	1309	1	p.	p.	NOUN
fnp-3025	1309	2	227	227	NUM
fnp-3025	1309	3	-	-	SYM
fnp-3025	1309	4	38	38	NUM
fnp-3025	1309	5	.	.	PUNCT
fnp-3025	1309	6	174	174	NUM
fnp-3025	1309	7	.	.	PUNCT
fnp-3025	1310	1	dickson	dickson	PROPN
fnp-3025	1310	2	,	,	PUNCT
fnp-3025	1310	3	t.c	t.c	PROPN
fnp-3025	1310	4	.	.	PROPN
fnp-3025	1310	5	and	and	CCONJ
fnp-3025	1310	6	j.c	j.c	PROPN
fnp-3025	1310	7	.	.	PROPN
fnp-3025	1310	8	vickers	vickers	PROPN
fnp-3025	1310	9	,	,	PUNCT
fnp-3025	1310	10	the	the	DET
fnp-3025	1310	11	morphological	morphological	ADJ
fnp-3025	1310	12	phenotype	phenotype	NOUN
fnp-3025	1310	13	of	of	ADP
fnp-3025	1310	14	beta	beta	NOUN
fnp-3025	1310	15	-	-	PUNCT
fnp-3025	1310	16	amyloid	amyloid	NOUN
fnp-3025	1310	17	plaques	plaque	NOUN
fnp-3025	1310	18	and	and	CCONJ
fnp-3025	1310	19	associated	associate	VERB
fnp-3025	1310	20	neuritic	neuritic	ADJ
fnp-3025	1310	21	changes	change	NOUN
fnp-3025	1310	22	in	in	ADP
fnp-3025	1310	23	alzheimer	alzheimer	PROPN
fnp-3025	1310	24	’s	’s	PART
fnp-3025	1310	25	disease	disease	NOUN
fnp-3025	1310	26	.	.	PUNCT
fnp-3025	1311	1	neuroscience	neuroscience	NOUN
fnp-3025	1311	2	,	,	PUNCT
fnp-3025	1311	3	2001	2001	NUM
fnp-3025	1311	4	.	.	PUNCT
fnp-3025	1312	1	105(1	105(1	NUM
fnp-3025	1312	2	):	):	PUNCT
fnp-3025	1312	3	p.	p.	NOUN
fnp-3025	1312	4	99	99	NUM
fnp-3025	1312	5	-	-	SYM
fnp-3025	1312	6	107	107	NUM
fnp-3025	1312	7	.	.	PUNCT
fnp-3025	1313	1	175	175	NUM
fnp-3025	1313	2	.	.	PUNCT
fnp-3025	1313	3	duyckaerts	duyckaert	NOUN
fnp-3025	1313	4	,	,	PUNCT
fnp-3025	1313	5	c.	c.	PROPN
fnp-3025	1313	6	,	,	PUNCT
fnp-3025	1313	7	b.	b.	PROPN
fnp-3025	1313	8	delatour	delatour	PROPN
fnp-3025	1313	9	,	,	PUNCT
fnp-3025	1313	10	and	and	CCONJ
fnp-3025	1313	11	m.c	m.c	PROPN
fnp-3025	1313	12	.	.	PROPN
fnp-3025	1313	13	potier	potier	NOUN
fnp-3025	1313	14	,	,	PUNCT
fnp-3025	1313	15	classification	classification	NOUN
fnp-3025	1313	16	and	and	CCONJ
fnp-3025	1313	17	basic	basic	ADJ
fnp-3025	1313	18	pathology	pathology	NOUN
fnp-3025	1313	19	of	of	ADP
fnp-3025	1313	20	alzheimer	alzheimer	PROPN
fnp-3025	1313	21	disease	disease	PROPN
fnp-3025	1313	22	.	.	PUNCT
fnp-3025	1314	1	acta	acta	PROPN
fnp-3025	1314	2	neuropathol	neuropathol	PROPN
fnp-3025	1314	3	,	,	PUNCT
fnp-3025	1314	4	2009	2009	NUM
fnp-3025	1314	5	.	.	PUNCT
fnp-3025	1315	1	118(1	118(1	NUM
fnp-3025	1315	2	):	):	PUNCT
fnp-3025	1315	3	p.	p.	NOUN
fnp-3025	1315	4	5	5	NUM
fnp-3025	1315	5	-	-	SYM
fnp-3025	1315	6	36	36	NUM
fnp-3025	1315	7	.	.	PUNCT
fnp-3025	1315	8	176	176	NUM
fnp-3025	1315	9	.	.	PUNCT
fnp-3025	1316	1	thal	thal	PROPN
fnp-3025	1316	2	,	,	PUNCT
fnp-3025	1316	3	d.r	d.r	PROPN
fnp-3025	1316	4	.	.	PROPN
fnp-3025	1316	5	,	,	PUNCT
fnp-3025	1316	6	et	et	PROPN
fnp-3025	1316	7	al	al	PROPN
fnp-3025	1316	8	.	.	PROPN
fnp-3025	1316	9	,	,	PUNCT
fnp-3025	1316	10	sequence	sequence	NOUN
fnp-3025	1316	11	of	of	ADP
fnp-3025	1316	12	abeta	abeta	ADJ
fnp-3025	1316	13	-	-	PUNCT
fnp-3025	1316	14	protein	protein	NOUN
fnp-3025	1316	15	deposition	deposition	NOUN
fnp-3025	1316	16	in	in	ADP
fnp-3025	1316	17	the	the	DET
fnp-3025	1316	18	human	human	ADJ
fnp-3025	1316	19	medial	medial	ADJ
fnp-3025	1316	20	temporal	temporal	ADJ
fnp-3025	1316	21	lobe	lobe	NOUN
fnp-3025	1316	22	.	.	PUNCT
fnp-3025	1317	1	j	j	PROPN
fnp-3025	1317	2	neuropathol	neuropathol	PROPN
fnp-3025	1317	3	exp	exp	PROPN
fnp-3025	1317	4	neurol	neurol	NOUN
fnp-3025	1317	5	,	,	PUNCT
fnp-3025	1317	6	2000	2000	NUM
fnp-3025	1317	7	.	.	PUNCT
fnp-3025	1318	1	59(8	59(8	NUM
fnp-3025	1318	2	):	):	PUNCT
fnp-3025	1319	1	p.	p.	NOUN
fnp-3025	1319	2	733	733	NUM
fnp-3025	1319	3	-	-	SYM
fnp-3025	1319	4	48	48	NUM
fnp-3025	1319	5	.	.	PUNCT
fnp-3025	1319	6	177	177	NUM
fnp-3025	1319	7	.	.	PUNCT
fnp-3025	1320	1	masters	master	NOUN
fnp-3025	1320	2	,	,	PUNCT
fnp-3025	1320	3	c.l	c.l	PROPN
fnp-3025	1320	4	.	.	PROPN
fnp-3025	1320	5	and	and	CCONJ
fnp-3025	1320	6	k.	k.	PROPN
fnp-3025	1320	7	beyreuther	beyreuther	PROPN
fnp-3025	1320	8	,	,	PUNCT
fnp-3025	1320	9	henryk	henryk	PROPN
fnp-3025	1320	10	m.	m.	PROPN
fnp-3025	1320	11	wisniewski	wisniewski	PROPN
fnp-3025	1320	12	and	and	CCONJ
fnp-3025	1320	13	the	the	DET
fnp-3025	1320	14	amyloid	amyloid	NOUN
fnp-3025	1320	15	theory	theory	NOUN
fnp-3025	1320	16	of	of	ADP
fnp-3025	1320	17	alzheimer	alzheimer	PROPN
fnp-3025	1320	18	’s	’s	PART
fnp-3025	1320	19	disease	disease	NOUN
fnp-3025	1320	20	.	.	PUNCT
fnp-3025	1321	1	j	j	PROPN
fnp-3025	1321	2	alzheimers	alzheimers	PROPN
fnp-3025	1321	3	dis	dis	PROPN
fnp-3025	1321	4	,	,	PUNCT
fnp-3025	1321	5	2001	2001	NUM
fnp-3025	1321	6	.	.	PUNCT
fnp-3025	1322	1	3(1	3(1	NUM
fnp-3025	1322	2	):	):	PUNCT
fnp-3025	1323	1	p.	p.	NOUN
fnp-3025	1323	2	83	83	NUM
fnp-3025	1323	3	-	-	SYM
fnp-3025	1323	4	86	86	NUM
fnp-3025	1323	5	.	.	PUNCT
fnp-3025	1323	6	178	178	NUM
fnp-3025	1323	7	.	.	PUNCT
fnp-3025	1324	1	wisniewski	wisniewski	PROPN
fnp-3025	1324	2	,	,	PUNCT
fnp-3025	1324	3	h.m	h.m	PROPN
fnp-3025	1324	4	.	.	PROPN
fnp-3025	1324	5	and	and	CCONJ
fnp-3025	1324	6	r.d	r.d	PROPN
fnp-3025	1324	7	.	.	PROPN
fnp-3025	1324	8	terry	terry	PROPN
fnp-3025	1324	9	,	,	PUNCT
fnp-3025	1324	10	reexamination	reexamination	NOUN
fnp-3025	1324	11	of	of	ADP
fnp-3025	1324	12	the	the	DET
fnp-3025	1324	13	pathogenesis	pathogenesis	NOUN
fnp-3025	1324	14	of	of	ADP
fnp-3025	1324	15	the	the	DET
fnp-3025	1324	16	senile	senile	ADJ
fnp-3025	1324	17	plaque	plaque	NOUN
fnp-3025	1324	18	,	,	PUNCT
fnp-3025	1324	19	in	in	ADP
fnp-3025	1324	20	progress	progress	NOUN
fnp-3025	1324	21	in	in	ADP
fnp-3025	1324	22	neuropathology	neuropathology	NOUN
fnp-3025	1324	23	,	,	PUNCT
fnp-3025	1324	24	h.m	h.m	PROPN
fnp-3025	1324	25	.	.	PROPN
fnp-3025	1324	26	zimmerman	zimmerman	PROPN
fnp-3025	1324	27	,	,	PUNCT
fnp-3025	1324	28	editor	editor	NOUN
fnp-3025	1324	29	.	.	PUNCT
fnp-3025	1325	1	1973	1973	NUM
fnp-3025	1325	2	,	,	PUNCT
fnp-3025	1325	3	grune	grune	NOUN
fnp-3025	1325	4	&	&	CCONJ
fnp-3025	1325	5	stratton	stratton	PROPN
fnp-3025	1325	6	:	:	PUNCT
fnp-3025	1325	7	new	new	PROPN
fnp-3025	1325	8	york	york	PROPN
fnp-3025	1325	9	.	.	PUNCT
fnp-3025	1326	1	p.	p.	NOUN
fnp-3025	1326	2	1	1	NUM
fnp-3025	1326	3	-	-	SYM
fnp-3025	1326	4	26	26	NUM
fnp-3025	1326	5	.	.	PUNCT
fnp-3025	1326	6	179	179	NUM
fnp-3025	1326	7	.	.	PUNCT
fnp-3025	1327	1	boon	boon	NOUN
fnp-3025	1327	2	,	,	PUNCT
fnp-3025	1327	3	b.d.c	b.d.c	PROPN
fnp-3025	1327	4	.	.	PROPN
fnp-3025	1327	5	,	,	PUNCT
fnp-3025	1327	6	et	et	PROPN
fnp-3025	1327	7	al	al	PROPN
fnp-3025	1327	8	.	.	PROPN
fnp-3025	1327	9	,	,	PUNCT
fnp-3025	1327	10	the	the	DET
fnp-3025	1327	11	coarse	coarse	ADV
fnp-3025	1327	12	-	-	PUNCT
fnp-3025	1327	13	grained	grain	VERB
fnp-3025	1327	14	plaque	plaque	NOUN
fnp-3025	1327	15	:	:	PUNCT
fnp-3025	1327	16	a	a	DET
fnp-3025	1327	17	divergent	divergent	ADJ
fnp-3025	1327	18	abeta	abeta	NOUN
fnp-3025	1327	19	plaque	plaque	NOUN
fnp-3025	1327	20	-	-	PUNCT
fnp-3025	1327	21	type	type	NOUN
fnp-3025	1327	22	in	in	ADP
fnp-3025	1327	23	early	early	ADJ
fnp-3025	1327	24	-	-	PUNCT
fnp-3025	1327	25	onset	onset	NOUN
fnp-3025	1327	26	alzheimer	alzheimer	PROPN
fnp-3025	1327	27	’s	’s	PART
fnp-3025	1327	28	disease	disease	NOUN
fnp-3025	1327	29	.	.	PUNCT
fnp-3025	1328	1	acta	acta	PROPN
fnp-3025	1328	2	neuropathol	neuropathol	PROPN
fnp-3025	1328	3	,	,	PUNCT
fnp-3025	1328	4	2020	2020	NUM
fnp-3025	1328	5	.	.	PUNCT
fnp-3025	1329	1	doi	doi	NOUN
fnp-3025	1329	2	:	:	PUNCT
fnp-3025	1329	3	10.1007	10.1007	NUM
fnp-3025	1329	4	/	/	SYM
fnp-3025	1329	5	s00401	s00401	NOUN
fnp-3025	1329	6	-	-	PUNCT
fnp-3025	1329	7	020	020	NUM
fnp-3025	1329	8	-	-	PUNCT
fnp-3025	1329	9	02198	02198	NUM
fnp-3025	1329	10	-	-	SYM
fnp-3025	1329	11	8	8	NUM
fnp-3025	1329	12	.	.	PUNCT
fnp-3025	1330	1	online	online	ADV
fnp-3025	1330	2	ahead	ahead	ADV
fnp-3025	1330	3	of	of	ADP
fnp-3025	1330	4	print	print	NOUN
fnp-3025	1330	5	.	.	PUNCT
fnp-3025	1331	1	pmid	pmid	NOUN
fnp-3025	1331	2	:	:	PUNCT
fnp-3025	1331	3	32926214	32926214	NUM
fnp-3025	1331	4	.	.	PUNCT
fnp-3025	1332	1	180	180	NUM
fnp-3025	1332	2	.	.	PUNCT
fnp-3025	1332	3	thal	thal	PROPN
fnp-3025	1332	4	,	,	PUNCT
fnp-3025	1332	5	d.r	d.r	PROPN
fnp-3025	1332	6	.	.	PROPN
fnp-3025	1332	7	,	,	PUNCT
fnp-3025	1332	8	et	et	PROPN
fnp-3025	1332	9	al	al	PROPN
fnp-3025	1332	10	.	.	PROPN
fnp-3025	1332	11	,	,	PUNCT
fnp-3025	1332	12	fleecy	fleecy	NOUN
fnp-3025	1332	13	amyloid	amyloid	NOUN
fnp-3025	1332	14	deposits	deposit	NOUN
fnp-3025	1332	15	in	in	ADP
fnp-3025	1332	16	the	the	DET
fnp-3025	1332	17	internal	internal	ADJ
fnp-3025	1332	18	layers	layer	NOUN
fnp-3025	1332	19	of	of	ADP
fnp-3025	1332	20	the	the	DET
fnp-3025	1332	21	human	human	ADJ
fnp-3025	1332	22	entorhinal	entorhinal	ADJ
fnp-3025	1332	23	cortex	cortex	NOUN
fnp-3025	1332	24	are	be	AUX
fnp-3025	1332	25	comprised	comprise	VERB
fnp-3025	1332	26	of	of	ADP
fnp-3025	1332	27	n	n	CCONJ
fnp-3025	1332	28	-	-	PUNCT
fnp-3025	1332	29	terminal	terminal	ADJ
fnp-3025	1332	30	truncated	truncate	VERB
fnp-3025	1332	31	fragments	fragment	NOUN
fnp-3025	1332	32	of	of	ADP
fnp-3025	1332	33	abeta	abeta	PROPN
fnp-3025	1332	34	.	.	PUNCT
fnp-3025	1333	1	j	j	PROPN
fnp-3025	1333	2	neuropathol	neuropathol	PROPN
fnp-3025	1333	3	exp	exp	PROPN
fnp-3025	1333	4	neurol	neurol	PROPN
fnp-3025	1333	5	,	,	PUNCT
fnp-3025	1333	6	1999	1999	NUM
fnp-3025	1333	7	.	.	PUNCT
fnp-3025	1334	1	58(2	58(2	NUM
fnp-3025	1334	2	):	):	PUNCT
fnp-3025	1334	3	p.	p.	NOUN
fnp-3025	1334	4	210	210	NUM
fnp-3025	1334	5	-	-	SYM
fnp-3025	1334	6	6	6	NUM
fnp-3025	1334	7	.	.	X
fnp-3025	1334	8	181	181	NUM
fnp-3025	1334	9	.	.	PUNCT
fnp-3025	1335	1	davies	davy	NOUN
fnp-3025	1335	2	,	,	PUNCT
fnp-3025	1335	3	c.a	c.a	PROPN
fnp-3025	1335	4	.	.	PROPN
fnp-3025	1335	5	and	and	CCONJ
fnp-3025	1335	6	d.m	d.m	PROPN
fnp-3025	1335	7	.	.	PUNCT
fnp-3025	1335	8	mann	mann	PROPN
fnp-3025	1335	9	,	,	PUNCT
fnp-3025	1335	10	is	be	AUX
fnp-3025	1335	11	the	the	DET
fnp-3025	1335	12	"	"	PUNCT
fnp-3025	1335	13	preamyloid	preamyloid	NOUN
fnp-3025	1335	14	"	"	PUNCT
fnp-3025	1335	15	of	of	ADP
fnp-3025	1335	16	diffuse	diffuse	PROPN
fnp-3025	1335	17	plaques	plaque	NOUN
fnp-3025	1335	18	in	in	ADP
fnp-3025	1335	19	alzheimer	alzheimer	PROPN
fnp-3025	1335	20	’s	’s	PART
fnp-3025	1335	21	disease	disease	NOUN
fnp-3025	1335	22	really	really	ADV
fnp-3025	1335	23	nonfibrillar	nonfibrillar	ADJ
fnp-3025	1335	24	?	?	PUNCT
fnp-3025	1336	1	am	be	AUX
fnp-3025	1336	2	j	j	PROPN
fnp-3025	1336	3	pathol	pathol	NOUN
fnp-3025	1336	4	,	,	PUNCT
fnp-3025	1336	5	1993	1993	NUM
fnp-3025	1336	6	.	.	PUNCT
fnp-3025	1337	1	143(6	143(6	NUM
fnp-3025	1337	2	):	):	PUNCT
fnp-3025	1337	3	p.	p.	NOUN
fnp-3025	1337	4	1594	1594	NUM
fnp-3025	1337	5	-	-	SYM
fnp-3025	1337	6	605	605	NUM
fnp-3025	1337	7	.	.	PUNCT
fnp-3025	1337	8	182	182	NUM
fnp-3025	1337	9	.	.	PUNCT
fnp-3025	1338	1	yamaguchi	yamaguchi	PROPN
fnp-3025	1338	2	,	,	PUNCT
fnp-3025	1338	3	h.	h.	PROPN
fnp-3025	1338	4	,	,	PUNCT
fnp-3025	1338	5	et	et	PROPN
fnp-3025	1338	6	al	al	PROPN
fnp-3025	1338	7	.	.	PROPN
fnp-3025	1338	8	,	,	PUNCT
fnp-3025	1338	9	electron	electron	NOUN
fnp-3025	1338	10	micrograph	micrograph	NOUN
fnp-3025	1338	11	of	of	ADP
fnp-3025	1338	12	diffuse	diffuse	ADJ
fnp-3025	1338	13	plaques	plaque	NOUN
fnp-3025	1338	14	.	.	PUNCT
fnp-3025	1339	1	initial	initial	ADJ
fnp-3025	1339	2	stage	stage	NOUN
fnp-3025	1339	3	of	of	ADP
fnp-3025	1339	4	senile	senile	ADJ
fnp-3025	1339	5	plaque	plaque	NOUN
fnp-3025	1339	6	formation	formation	NOUN
fnp-3025	1339	7	in	in	ADP
fnp-3025	1339	8	the	the	DET
fnp-3025	1339	9	alzheimer	alzheimer	PROPN
fnp-3025	1339	10	brain	brain	NOUN
fnp-3025	1339	11	.	.	PUNCT
fnp-3025	1340	1	am	be	AUX
fnp-3025	1340	2	j	j	PROPN
fnp-3025	1340	3	pathol	pathol	NOUN
fnp-3025	1340	4	,	,	PUNCT
fnp-3025	1340	5	1989	1989	NUM
fnp-3025	1340	6	.	.	PUNCT
fnp-3025	1341	1	135(4	135(4	NUM
fnp-3025	1341	2	):	):	PUNCT
fnp-3025	1341	3	p.	p.	NOUN
fnp-3025	1341	4	593	593	NUM
fnp-3025	1341	5	-	-	SYM
fnp-3025	1341	6	7	7	NUM
fnp-3025	1341	7	.	.	NOUN
fnp-3025	1341	8	183	183	NUM
fnp-3025	1341	9	.	.	PUNCT
fnp-3025	1342	1	yamaguchi	yamaguchi	PROPN
fnp-3025	1342	2	,	,	PUNCT
fnp-3025	1342	3	h.	h.	PROPN
fnp-3025	1342	4	,	,	PUNCT
fnp-3025	1342	5	et	et	PROPN
fnp-3025	1342	6	al	al	PROPN
fnp-3025	1342	7	.	.	PROPN
fnp-3025	1342	8	,	,	PUNCT
fnp-3025	1342	9	ultrastructure	ultrastructure	NOUN
fnp-3025	1342	10	of	of	ADP
fnp-3025	1342	11	diffuse	diffuse	ADJ
fnp-3025	1342	12	plaques	plaque	NOUN
fnp-3025	1342	13	in	in	ADP
fnp-3025	1342	14	senile	senile	ADJ
fnp-3025	1342	15	dementia	dementia	NOUN
fnp-3025	1342	16	of	of	ADP
fnp-3025	1342	17	the	the	DET
fnp-3025	1342	18	alzheimer	alzheimer	PROPN
fnp-3025	1342	19	type	type	NOUN
fnp-3025	1342	20	:	:	PUNCT
fnp-3025	1342	21	comparison	comparison	NOUN
fnp-3025	1342	22	with	with	ADP
fnp-3025	1342	23	primitive	primitive	ADJ
fnp-3025	1342	24	plaques	plaque	NOUN
fnp-3025	1342	25	.	.	PUNCT
fnp-3025	1343	1	acta	acta	PROPN
fnp-3025	1343	2	neuropathol	neuropathol	PROPN
fnp-3025	1343	3	,	,	PUNCT
fnp-3025	1343	4	1991	1991	NUM
fnp-3025	1343	5	.	.	PUNCT
fnp-3025	1344	1	82(1	82(1	NOUN
fnp-3025	1344	2	):	):	PUNCT
fnp-3025	1344	3	p.	p.	NOUN
fnp-3025	1344	4	13	13	NUM
fnp-3025	1344	5	-	-	SYM
fnp-3025	1344	6	20	20	NUM
fnp-3025	1344	7	.	.	PUNCT
fnp-3025	1345	1	184	184	NUM
fnp-3025	1345	2	.	.	PUNCT
fnp-3025	1346	1	wisniewski	wisniewski	PROPN
fnp-3025	1346	2	,	,	PUNCT
fnp-3025	1346	3	h.m	h.m	PROPN
fnp-3025	1346	4	.	.	PROPN
fnp-3025	1346	5	,	,	PUNCT
fnp-3025	1346	6	et	et	PROPN
fnp-3025	1346	7	al	al	PROPN
fnp-3025	1346	8	.	.	PROPN
fnp-3025	1346	9	,	,	PUNCT
fnp-3025	1346	10	diffuse	diffuse	NOUN
fnp-3025	1346	11	,	,	PUNCT
fnp-3025	1346	12	lake	lake	NOUN
fnp-3025	1346	13	-	-	PUNCT
fnp-3025	1346	14	like	like	ADJ
fnp-3025	1346	15	amyloid	amyloid	NOUN
fnp-3025	1346	16	-	-	PUNCT
fnp-3025	1346	17	beta	beta	NOUN
fnp-3025	1346	18	deposits	deposit	NOUN
fnp-3025	1346	19	in	in	ADP
fnp-3025	1346	20	the	the	DET
fnp-3025	1346	21	parvopyramidal	parvopyramidal	ADJ
fnp-3025	1346	22	layer	layer	NOUN
fnp-3025	1346	23	of	of	ADP
fnp-3025	1346	24	the	the	DET
fnp-3025	1346	25	presubiculum	presubiculum	NOUN
fnp-3025	1346	26	in	in	ADP
fnp-3025	1346	27	alzheimer	alzheimer	PROPN
fnp-3025	1346	28	disease	disease	PROPN
fnp-3025	1346	29	.	.	PUNCT
fnp-3025	1347	1	j	j	PROPN
fnp-3025	1347	2	neuropathol	neuropathol	PROPN
fnp-3025	1347	3	exp	exp	PROPN
fnp-3025	1347	4	neurol	neurol	PROPN
fnp-3025	1347	5	,	,	PUNCT
fnp-3025	1347	6	1998	1998	NUM
fnp-3025	1347	7	.	.	PUNCT
fnp-3025	1348	1	57(7	57(7	NUM
fnp-3025	1348	2	):	):	PUNCT
fnp-3025	1348	3	p.	p.	NOUN
fnp-3025	1348	4	674	674	NUM
fnp-3025	1348	5	-	-	SYM
fnp-3025	1348	6	83	83	NUM
fnp-3025	1348	7	.	.	PUNCT
fnp-3025	1348	8	185	185	NUM
fnp-3025	1348	9	.	.	PUNCT
fnp-3025	1349	1	fischer	fischer	PROPN
fnp-3025	1349	2	,	,	PUNCT
fnp-3025	1349	3	o.	o.	PROPN
fnp-3025	1349	4	,	,	PUNCT
fnp-3025	1349	5	die	die	VERB
fnp-3025	1349	6	presbyophrene	presbyophrene	NOUN
fnp-3025	1349	7	demenz	demenz	PROPN
fnp-3025	1349	8	,	,	PUNCT
fnp-3025	1349	9	deren	deren	PROPN
fnp-3025	1349	10	anatomische	anatomische	PROPN
fnp-3025	1349	11	grundlage	grundlage	PROPN
fnp-3025	1349	12	und	und	PROPN
fnp-3025	1349	13	klinische	klinische	NOUN
fnp-3025	1349	14	abgrenzung	abgrenzung	PROPN
fnp-3025	1349	15	.	.	PUNCT
fnp-3025	1350	1	zeitschrift	zeitschrift	PROPN
fnp-3025	1350	2	für	für	PROPN
fnp-3025	1350	3	die	die	VERB
fnp-3025	1350	4	gesamte	gesamte	PROPN
fnp-3025	1350	5	neurologie	neurologie	X
fnp-3025	1350	6	und	und	VERB
fnp-3025	1350	7	psychiatrie	psychiatrie	NOUN
fnp-3025	1350	8	,	,	PUNCT
fnp-3025	1350	9	1910	1910	NUM
fnp-3025	1350	10	.	.	PUNCT
fnp-3025	1351	1	3	3	NUM
fnp-3025	1351	2	:	:	PUNCT
fnp-3025	1351	3	p.	p.	NOUN
fnp-3025	1351	4	371	371	NUM
fnp-3025	1351	5	-	-	SYM
fnp-3025	1351	6	471	471	NUM
fnp-3025	1351	7	.	.	NOUN
fnp-3025	1351	8	186	186	NUM
fnp-3025	1351	9	.	.	PUNCT
fnp-3025	1352	1	thal	thal	PROPN
fnp-3025	1352	2	,	,	PUNCT
fnp-3025	1352	3	d.r	d.r	PROPN
fnp-3025	1352	4	.	.	PROPN
fnp-3025	1352	5	,	,	PUNCT
fnp-3025	1352	6	et	et	PROPN
fnp-3025	1352	7	al	al	PROPN
fnp-3025	1352	8	.	.	PROPN
fnp-3025	1352	9	,	,	PUNCT
fnp-3025	1352	10	amyloid	amyloid	NOUN
fnp-3025	1352	11	beta	beta	NOUN
fnp-3025	1352	12	-	-	PUNCT
fnp-3025	1352	13	protein	protein	NOUN
fnp-3025	1352	14	(	(	PUNCT
fnp-3025	1352	15	abeta)-containing	abeta)-containe	VERB
fnp-3025	1352	16	astrocytes	astrocyte	NOUN
fnp-3025	1352	17	are	be	AUX
fnp-3025	1352	18	located	locate	VERB
fnp-3025	1352	19	preferentially	preferentially	ADV
fnp-3025	1352	20	near	near	ADP
fnp-3025	1352	21	n	n	CCONJ
fnp-3025	1352	22	-	-	PUNCT
fnp-3025	1352	23	terminal	terminal	NOUN
fnp-3025	1352	24	-	-	PUNCT
fnp-3025	1352	25	truncated	truncate	VERB
fnp-3025	1352	26	abeta	abeta	NOUN
fnp-3025	1352	27	deposits	deposit	NOUN
fnp-3025	1352	28	in	in	ADP
fnp-3025	1352	29	the	the	DET
fnp-3025	1352	30	human	human	ADJ
fnp-3025	1352	31	entorhinal	entorhinal	ADJ
fnp-3025	1352	32	cortex	cortex	NOUN
fnp-3025	1352	33	.	.	PUNCT
fnp-3025	1353	1	acta	acta	PROPN
fnp-3025	1353	2	neuropathol	neuropathol	PROPN
fnp-3025	1353	3	,	,	PUNCT
fnp-3025	1353	4	2000	2000	NUM
fnp-3025	1353	5	.	.	PUNCT
fnp-3025	1354	1	100(6	100(6	NUM
fnp-3025	1354	2	):	):	PUNCT
fnp-3025	1354	3	p.	p.	NOUN
fnp-3025	1354	4	608	608	NUM
fnp-3025	1354	5	-	-	SYM
fnp-3025	1354	6	17	17	NUM
fnp-3025	1354	7	.	.	PUNCT
fnp-3025	1355	1	187	187	NUM
fnp-3025	1355	2	.	.	PUNCT
fnp-3025	1356	1	allsop	allsop	PROPN
fnp-3025	1356	2	,	,	PUNCT
fnp-3025	1356	3	d.	d.	PROPN
fnp-3025	1356	4	,	,	PUNCT
fnp-3025	1356	5	et	et	PROPN
fnp-3025	1356	6	al	al	PROPN
fnp-3025	1356	7	.	.	PROPN
fnp-3025	1356	8	,	,	PUNCT
fnp-3025	1356	9	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1356	10	tangles	tangle	NOUN
fnp-3025	1356	11	in	in	ADP
fnp-3025	1356	12	some	some	DET
fnp-3025	1356	13	cases	case	NOUN
fnp-3025	1356	14	of	of	ADP
fnp-3025	1356	15	dementia	dementia	NOUN
fnp-3025	1356	16	pugilistica	pugilistica	NOUN
fnp-3025	1356	17	share	share	VERB
fnp-3025	1356	18	antigens	antigen	NOUN
fnp-3025	1356	19	with	with	ADP
fnp-3025	1356	20	amyloid	amyloid	NOUN
fnp-3025	1356	21	beta	beta	NOUN
fnp-3025	1356	22	-	-	PUNCT
fnp-3025	1356	23	protein	protein	NOUN
fnp-3025	1356	24	of	of	ADP
fnp-3025	1356	25	alzheimer	alzheimer	PROPN
fnp-3025	1356	26	’s	’s	PART
fnp-3025	1356	27	disease	disease	NOUN
fnp-3025	1356	28	.	.	PUNCT
fnp-3025	1357	1	am	be	AUX
fnp-3025	1357	2	j	j	PROPN
fnp-3025	1357	3	pathol	pathol	NOUN
fnp-3025	1357	4	,	,	PUNCT
fnp-3025	1357	5	1990	1990	NUM
fnp-3025	1357	6	.	.	PUNCT
fnp-3025	1358	1	136(2	136(2	NUM
fnp-3025	1358	2	):	):	PUNCT
fnp-3025	1359	1	p.	p.	NOUN
fnp-3025	1359	2	255	255	NUM
fnp-3025	1359	3	-	-	SYM
fnp-3025	1359	4	60	60	NUM
fnp-3025	1359	5	.	.	PUNCT
fnp-3025	1359	6	188	188	NUM
fnp-3025	1359	7	.	.	PUNCT
fnp-3025	1360	1	bondareff	bondareff	PROPN
fnp-3025	1360	2	,	,	PUNCT
fnp-3025	1360	3	w.	w.	PROPN
fnp-3025	1360	4	,	,	PUNCT
fnp-3025	1360	5	et	et	PROPN
fnp-3025	1360	6	al	al	PROPN
fnp-3025	1360	7	.	.	PROPN
fnp-3025	1360	8	,	,	PUNCT
fnp-3025	1360	9	molecular	molecular	ADJ
fnp-3025	1360	10	analysis	analysis	NOUN
fnp-3025	1360	11	of	of	ADP
fnp-3025	1360	12	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1360	13	degeneration	degeneration	NOUN
fnp-3025	1360	14	in	in	ADP
fnp-3025	1360	15	alzheimer	alzheimer	PROPN
fnp-3025	1360	16	’s	’s	PART
fnp-3025	1360	17	disease	disease	NOUN
fnp-3025	1360	18	.	.	PUNCT
fnp-3025	1361	1	an	an	DET
fnp-3025	1361	2	immunohistochemical	immunohistochemical	ADJ
fnp-3025	1361	3	study	study	NOUN
fnp-3025	1361	4	.	.	PUNCT
fnp-3025	1362	1	am	be	AUX
fnp-3025	1362	2	j	j	PROPN
fnp-3025	1362	3	pathol	pathol	NOUN
fnp-3025	1362	4	,	,	PUNCT
fnp-3025	1362	5	1990	1990	NUM
fnp-3025	1362	6	.	.	PUNCT
fnp-3025	1363	1	137(3	137(3	NUM
fnp-3025	1363	2	):	):	PUNCT
fnp-3025	1364	1	p.	p.	NOUN
fnp-3025	1364	2	711	711	NUM
fnp-3025	1364	3	-	-	SYM
fnp-3025	1364	4	23	23	NUM
fnp-3025	1364	5	.	.	PUNCT
fnp-3025	1364	6	189	189	NUM
fnp-3025	1364	7	.	.	PUNCT
fnp-3025	1365	1	hyman	hyman	PROPN
fnp-3025	1365	2	,	,	PUNCT
fnp-3025	1365	3	b.t	b.t	PROPN
fnp-3025	1365	4	.	.	PROPN
fnp-3025	1365	5	,	,	PUNCT
fnp-3025	1365	6	et	et	PROPN
fnp-3025	1365	7	al	al	PROPN
fnp-3025	1365	8	.	.	PROPN
fnp-3025	1365	9	,	,	PUNCT
fnp-3025	1365	10	a4	a4	VERB
fnp-3025	1365	11	amyloid	amyloid	NOUN
fnp-3025	1365	12	protein	protein	NOUN
fnp-3025	1365	13	immunoreactivity	immunoreactivity	NOUN
fnp-3025	1365	14	is	be	AUX
fnp-3025	1365	15	present	present	ADJ
fnp-3025	1365	16	in	in	ADP
fnp-3025	1365	17	alzheimer	alzheimer	PROPN
fnp-3025	1365	18	’s	’s	PART
fnp-3025	1365	19	disease	disease	NOUN
fnp-3025	1365	20	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1365	21	tangles	tangle	NOUN
fnp-3025	1365	22	.	.	PUNCT
fnp-3025	1366	1	neurosci	neurosci	PROPN
fnp-3025	1366	2	lett	lett	PROPN
fnp-3025	1366	3	,	,	PUNCT
fnp-3025	1366	4	1989	1989	NUM
fnp-3025	1366	5	.	.	PUNCT
fnp-3025	1367	1	101(3	101(3	NUM
fnp-3025	1367	2	):	):	PUNCT
fnp-3025	1368	1	p.	p.	NOUN
fnp-3025	1368	2	352	352	NUM
fnp-3025	1368	3	-	-	SYM
fnp-3025	1368	4	5	5	NUM
fnp-3025	1368	5	.	.	NOUN
fnp-3025	1368	6	190	190	NUM
fnp-3025	1368	7	.	.	PUNCT
fnp-3025	1369	1	sherriff	sherriff	PROPN
fnp-3025	1369	2	,	,	PUNCT
fnp-3025	1369	3	f.e	f.e	PROPN
fnp-3025	1369	4	.	.	PROPN
fnp-3025	1369	5	,	,	PUNCT
fnp-3025	1369	6	l.r	l.r	PROPN
fnp-3025	1369	7	.	.	PROPN
fnp-3025	1369	8	bridges	bridge	NOUN
fnp-3025	1369	9	,	,	PUNCT
fnp-3025	1369	10	and	and	CCONJ
fnp-3025	1369	11	d.s	d.s	PROPN
fnp-3025	1369	12	.	.	PROPN
fnp-3025	1369	13	de	de	PROPN
fnp-3025	1369	14	souza	souza	PROPN
fnp-3025	1369	15	,	,	PUNCT
fnp-3025	1369	16	non	non	ADJ
fnp-3025	1369	17	-	-	ADJ
fnp-3025	1369	18	alzheimer	alzheimer	ADJ
fnp-3025	1369	19	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1369	20	tangles	tangle	NOUN
fnp-3025	1369	21	show	show	VERB
fnp-3025	1369	22	beta	beta	NOUN
fnp-3025	1369	23	-	-	PUNCT
fnp-3025	1369	24	amyloid	amyloid	NOUN
fnp-3025	1369	25	-	-	PUNCT
fnp-3025	1369	26	like	like	ADJ
fnp-3025	1369	27	immunoreactivity	immunoreactivity	NOUN
fnp-3025	1369	28	.	.	PUNCT
fnp-3025	1370	1	neuroreport	neuroreport	NOUN
fnp-3025	1370	2	,	,	PUNCT
fnp-3025	1370	3	1994	1994	NUM
fnp-3025	1370	4	.	.	PUNCT
fnp-3025	1371	1	5(15	5(15	NUM
fnp-3025	1371	2	):	):	PUNCT
fnp-3025	1371	3	p.	p.	NOUN
fnp-3025	1371	4	1897	1897	NUM
fnp-3025	1371	5	-	-	SYM
fnp-3025	1371	6	900	900	NUM
fnp-3025	1371	7	.	.	X
fnp-3025	1372	1	191	191	NUM
fnp-3025	1372	2	.	.	X
fnp-3025	1373	1	tabaton	tabaton	PROPN
fnp-3025	1373	2	,	,	PUNCT
fnp-3025	1373	3	m.	m.	NOUN
fnp-3025	1373	4	,	,	PUNCT
fnp-3025	1373	5	et	et	PROPN
fnp-3025	1373	6	al	al	PROPN
fnp-3025	1373	7	.	.	PROPN
fnp-3025	1373	8	,	,	PUNCT
fnp-3025	1373	9	ultrastructural	ultrastructural	ADJ
fnp-3025	1373	10	localization	localization	NOUN
fnp-3025	1373	11	of	of	ADP
fnp-3025	1373	12	beta	beta	NOUN
fnp-3025	1373	13	-	-	PUNCT
fnp-3025	1373	14	amyloid	amyloid	NOUN
fnp-3025	1373	15	,	,	PUNCT
fnp-3025	1373	16	tau	tau	PROPN
fnp-3025	1373	17	,	,	PUNCT
fnp-3025	1373	18	and	and	CCONJ
fnp-3025	1373	19	ubiquitin	ubiquitin	ADJ
fnp-3025	1373	20	epitopes	epitope	NOUN
fnp-3025	1373	21	in	in	ADP
fnp-3025	1373	22	extracellular	extracellular	ADJ
fnp-3025	1373	23	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1373	24	tangles	tangle	NOUN
fnp-3025	1373	25	.	.	PUNCT
fnp-3025	1374	1	proc	proc	PROPN
fnp-3025	1374	2	natl	natl	PROPN
fnp-3025	1374	3	acad	acad	PROPN
fnp-3025	1374	4	sci	sci	PROPN
fnp-3025	1374	5	u	u	PROPN
fnp-3025	1374	6	s	s	NOUN
fnp-3025	1374	7	a	a	PRON
fnp-3025	1374	8	,	,	PUNCT
fnp-3025	1374	9	1991	1991	NUM
fnp-3025	1374	10	.	.	PUNCT
fnp-3025	1375	1	88(6	88(6	NUM
fnp-3025	1375	2	):	):	PUNCT
fnp-3025	1376	1	p.	p.	NOUN
fnp-3025	1376	2	2098	2098	NUM
fnp-3025	1376	3	-	-	SYM
fnp-3025	1376	4	102	102	NUM
fnp-3025	1376	5	.	.	PUNCT
fnp-3025	1376	6	192	192	NUM
fnp-3025	1376	7	.	.	PUNCT
fnp-3025	1377	1	yamaguchi	yamaguchi	PROPN
fnp-3025	1377	2	,	,	PUNCT
fnp-3025	1377	3	h.	h.	PROPN
fnp-3025	1377	4	,	,	PUNCT
fnp-3025	1377	5	et	et	PROPN
fnp-3025	1377	6	al	al	PROPN
fnp-3025	1377	7	.	.	PROPN
fnp-3025	1377	8	,	,	PUNCT
fnp-3025	1377	9	secondary	secondary	ADJ
fnp-3025	1377	10	deposition	deposition	NOUN
fnp-3025	1377	11	of	of	ADP
fnp-3025	1377	12	beta	beta	ADJ
fnp-3025	1377	13	amyloid	amyloid	NOUN
fnp-3025	1377	14	within	within	ADP
fnp-3025	1377	15	extracellular	extracellular	ADJ
fnp-3025	1377	16	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1377	17	tangles	tangle	NOUN
fnp-3025	1377	18	in	in	ADP
fnp-3025	1377	19	alzheimer	alzheimer	ADJ
fnp-3025	1377	20	-	-	PUNCT
fnp-3025	1377	21	type	type	NOUN
fnp-3025	1377	22	dementia	dementia	NOUN
fnp-3025	1377	23	.	.	PUNCT
fnp-3025	1377	24	am	be	AUX
fnp-3025	1377	25	j	j	PROPN
fnp-3025	1377	26	pathol	pathol	NOUN
fnp-3025	1377	27	,	,	PUNCT
fnp-3025	1377	28	1991	1991	NUM
fnp-3025	1377	29	.	.	PUNCT
fnp-3025	1378	1	138(3	138(3	NUM
fnp-3025	1378	2	):	):	PUNCT
fnp-3025	1378	3	p.	p.	NOUN
fnp-3025	1378	4	699	699	NUM
fnp-3025	1378	5	-	-	SYM
fnp-3025	1378	6	705	705	NUM
fnp-3025	1378	7	.	.	NOUN
fnp-3025	1378	8	193	193	NUM
fnp-3025	1378	9	.	.	PUNCT
fnp-3025	1379	1	zemlan	zemlan	PROPN
fnp-3025	1379	2	,	,	PUNCT
fnp-3025	1379	3	f.p	f.p	PROPN
fnp-3025	1379	4	.	.	PROPN
fnp-3025	1379	5	,	,	PUNCT
fnp-3025	1379	6	et	et	PROPN
fnp-3025	1379	7	al	al	PROPN
fnp-3025	1379	8	.	.	PROPN
fnp-3025	1379	9	,	,	PUNCT
fnp-3025	1379	10	alzheimer	alzheimer	PROPN
fnp-3025	1379	11	’s	’s	PART
fnp-3025	1379	12	paired	pair	VERB
fnp-3025	1379	13	helical	helical	ADJ
fnp-3025	1379	14	filaments	filament	NOUN
fnp-3025	1379	15	:	:	PUNCT
fnp-3025	1379	16	amyloid	amyloid	NOUN
fnp-3025	1379	17	precursor	precursor	NOUN
fnp-3025	1379	18	protein	protein	NOUN
fnp-3025	1379	19	epitope	epitope	PROPN
fnp-3025	1379	20	mapping	mapping	NOUN
fnp-3025	1379	21	.	.	PUNCT
fnp-3025	1380	1	brain	brain	NOUN
fnp-3025	1380	2	res	re	NOUN
fnp-3025	1380	3	bull	bull	NOUN
fnp-3025	1380	4	,	,	PUNCT
fnp-3025	1380	5	1994	1994	NUM
fnp-3025	1380	6	.	.	PUNCT
fnp-3025	1381	1	33(4	33(4	NUM
fnp-3025	1381	2	):	):	PUNCT
fnp-3025	1381	3	p.	p.	NOUN
fnp-3025	1381	4	387	387	NUM
fnp-3025	1381	5	-	-	SYM
fnp-3025	1381	6	92	92	NUM
fnp-3025	1381	7	.	.	PUNCT
fnp-3025	1382	1	194	194	NUM
fnp-3025	1382	2	.	.	PUNCT
fnp-3025	1382	3	walker	walker	PROPN
fnp-3025	1382	4	,	,	PUNCT
fnp-3025	1382	5	l.c	l.c	PROPN
fnp-3025	1382	6	.	.	PROPN
fnp-3025	1382	7	,	,	PUNCT
fnp-3025	1382	8	et	et	PROPN
fnp-3025	1382	9	al	al	PROPN
fnp-3025	1382	10	.	.	PROPN
fnp-3025	1382	11	,	,	PUNCT
fnp-3025	1382	12	apolipoprotein	apolipoprotein	ADJ
fnp-3025	1382	13	e4	e4	PROPN
fnp-3025	1382	14	promotes	promote	VERB
fnp-3025	1382	15	the	the	DET
fnp-3025	1382	16	early	early	ADJ
fnp-3025	1382	17	deposition	deposition	NOUN
fnp-3025	1382	18	of	of	ADP
fnp-3025	1382	19	abeta42	abeta42	NOUN
fnp-3025	1382	20	and	and	CCONJ
fnp-3025	1382	21	then	then	ADV
fnp-3025	1382	22	abeta40	abeta40	NOUN
fnp-3025	1382	23	in	in	ADP
fnp-3025	1382	24	the	the	DET
fnp-3025	1382	25	elderly	elderly	ADJ
fnp-3025	1382	26	.	.	PUNCT
fnp-3025	1383	1	acta	acta	PROPN
fnp-3025	1383	2	neuropathol	neuropathol	PROPN
fnp-3025	1383	3	,	,	PUNCT
fnp-3025	1383	4	2000	2000	NUM
fnp-3025	1383	5	.	.	PUNCT
fnp-3025	1384	1	100(1	100(1	NUM
fnp-3025	1384	2	):	):	PUNCT
fnp-3025	1385	1	p.	p.	NOUN
fnp-3025	1385	2	36	36	NUM
fnp-3025	1385	3	-	-	SYM
fnp-3025	1385	4	42	42	NUM
fnp-3025	1385	5	.	.	PUNCT
fnp-3025	1385	6	195	195	NUM
fnp-3025	1385	7	.	.	PUNCT
fnp-3025	1386	1	mott	mott	PROPN
fnp-3025	1386	2	,	,	PUNCT
fnp-3025	1386	3	r.t	r.t	PROPN
fnp-3025	1386	4	.	.	PROPN
fnp-3025	1386	5	and	and	CCONJ
fnp-3025	1386	6	c.m	c.m	PROPN
fnp-3025	1386	7	.	.	PROPN
fnp-3025	1386	8	hulette	hulette	PROPN
fnp-3025	1386	9	,	,	PUNCT
fnp-3025	1386	10	neuropathology	neuropathology	NOUN
fnp-3025	1386	11	of	of	ADP
fnp-3025	1386	12	alzheimer	alzheimer	PROPN
fnp-3025	1386	13	’s	’s	PART
fnp-3025	1386	14	disease	disease	NOUN
fnp-3025	1386	15	.	.	PUNCT
fnp-3025	1387	1	neuroimaging	neuroimage	VERB
fnp-3025	1387	2	clin	clin	PROPN
fnp-3025	1387	3	n	n	PRON
fnp-3025	1387	4	am	be	AUX
fnp-3025	1387	5	,	,	PUNCT
fnp-3025	1387	6	2005	2005	NUM
fnp-3025	1387	7	.	.	PUNCT
fnp-3025	1388	1	15(4	15(4	NUM
fnp-3025	1388	2	):	):	PUNCT
fnp-3025	1388	3	p.	p.	NOUN
fnp-3025	1388	4	755	755	NUM
fnp-3025	1388	5	-	-	SYM
fnp-3025	1388	6	65	65	NUM
fnp-3025	1388	7	,	,	PUNCT
fnp-3025	1388	8	ix	ix	PROPN
fnp-3025	1388	9	.	.	PUNCT
fnp-3025	1388	10	196	196	NUM
fnp-3025	1388	11	.	.	PUNCT
fnp-3025	1389	1	edgar	edgar	PROPN
fnp-3025	1389	2	,	,	PUNCT
fnp-3025	1389	3	j.r	j.r	PROPN
fnp-3025	1389	4	.	.	PROPN
fnp-3025	1389	5	,	,	PUNCT
fnp-3025	1389	6	et	et	PROPN
fnp-3025	1389	7	al	al	PROPN
fnp-3025	1389	8	.	.	PROPN
fnp-3025	1389	9	,	,	PUNCT
fnp-3025	1389	10	escrts	escrts	AUX
fnp-3025	1389	11	regulate	regulate	VERB
fnp-3025	1389	12	amyloid	amyloid	NOUN
fnp-3025	1389	13	precursor	precursor	NOUN
fnp-3025	1389	14	protein	protein	NOUN
fnp-3025	1389	15	sorting	sort	VERB
fnp-3025	1389	16	in	in	ADP
fnp-3025	1389	17	multivesicular	multivesicular	ADJ
fnp-3025	1389	18	bodies	body	NOUN
fnp-3025	1389	19	and	and	CCONJ
fnp-3025	1389	20	intracellular	intracellular	ADJ
fnp-3025	1389	21	amyloid	amyloid	NOUN
fnp-3025	1389	22	-	-	PUNCT
fnp-3025	1389	23	beta	beta	NOUN
fnp-3025	1389	24	accumulation	accumulation	NOUN
fnp-3025	1389	25	.	.	PUNCT
fnp-3025	1390	1	j	j	PROPN
fnp-3025	1390	2	cell	cell	PROPN
fnp-3025	1390	3	sci	sci	PROPN
fnp-3025	1390	4	,	,	PUNCT
fnp-3025	1390	5	2015	2015	NUM
fnp-3025	1390	6	.	.	PUNCT
fnp-3025	1391	1	128(14	128(14	NUM
fnp-3025	1391	2	):	):	PUNCT
fnp-3025	1391	3	p.	p.	NOUN
fnp-3025	1391	4	2520	2520	NUM
fnp-3025	1391	5	-	-	SYM
fnp-3025	1391	6	8	8	NUM
fnp-3025	1391	7	.	.	SYM
fnp-3025	1391	8	197	197	NUM
fnp-3025	1391	9	.	.	PUNCT
fnp-3025	1392	1	langui	langui	PROPN
fnp-3025	1392	2	,	,	PUNCT
fnp-3025	1392	3	d.	d.	PROPN
fnp-3025	1392	4	,	,	PUNCT
fnp-3025	1392	5	et	et	PROPN
fnp-3025	1392	6	al	al	PROPN
fnp-3025	1392	7	.	.	PROPN
fnp-3025	1392	8	,	,	PUNCT
fnp-3025	1392	9	subcellular	subcellular	ADJ
fnp-3025	1392	10	topography	topography	NOUN
fnp-3025	1392	11	of	of	ADP
fnp-3025	1392	12	neuronal	neuronal	ADJ
fnp-3025	1392	13	abeta	abeta	NOUN
fnp-3025	1392	14	peptide	peptide	NOUN
fnp-3025	1392	15	in	in	ADP
fnp-3025	1392	16	appxps1	appxps1	NOUN
fnp-3025	1392	17	transgenic	transgenic	NOUN
fnp-3025	1392	18	mice	mouse	NOUN
fnp-3025	1392	19	.	.	PUNCT
fnp-3025	1393	1	am	be	AUX
fnp-3025	1393	2	j	j	PROPN
fnp-3025	1393	3	pathol	pathol	NOUN
fnp-3025	1393	4	,	,	PUNCT
fnp-3025	1393	5	2004	2004	NUM
fnp-3025	1393	6	.	.	PUNCT
fnp-3025	1394	1	165(5	165(5	NUM
fnp-3025	1394	2	):	):	PUNCT
fnp-3025	1394	3	p.	p.	NOUN
fnp-3025	1394	4	1465	1465	NUM
fnp-3025	1394	5	-	-	SYM
fnp-3025	1394	6	77	77	NUM
fnp-3025	1394	7	.	.	PUNCT
fnp-3025	1395	1	198	198	NUM
fnp-3025	1395	2	.	.	PUNCT
fnp-3025	1396	1	rajendran	rajendran	PROPN
fnp-3025	1396	2	,	,	PUNCT
fnp-3025	1396	3	l.	l.	PROPN
fnp-3025	1396	4	,	,	PUNCT
fnp-3025	1396	5	et	et	PROPN
fnp-3025	1396	6	al	al	PROPN
fnp-3025	1396	7	.	.	PROPN
fnp-3025	1396	8	,	,	PUNCT
fnp-3025	1396	9	alzheimer	alzheimer	PROPN
fnp-3025	1396	10	’s	’s	PART
fnp-3025	1396	11	disease	disease	NOUN
fnp-3025	1396	12	beta	beta	NOUN
fnp-3025	1396	13	-	-	PUNCT
fnp-3025	1396	14	amyloid	amyloid	NOUN
fnp-3025	1396	15	peptides	peptide	NOUN
fnp-3025	1396	16	are	be	AUX
fnp-3025	1396	17	released	release	VERB
fnp-3025	1396	18	in	in	ADP
fnp-3025	1396	19	association	association	NOUN
fnp-3025	1396	20	with	with	ADP
fnp-3025	1396	21	exosomes	exosome	NOUN
fnp-3025	1396	22	.	.	PUNCT
fnp-3025	1397	1	proc	proc	PROPN
fnp-3025	1397	2	natl	natl	PROPN
fnp-3025	1397	3	acad	acad	PROPN
fnp-3025	1397	4	sci	sci	PROPN
fnp-3025	1397	5	u	u	PROPN
fnp-3025	1397	6	s	s	PROPN
fnp-3025	1397	7	a	a	PRON
fnp-3025	1397	8	,	,	PUNCT
fnp-3025	1397	9	2006	2006	NUM
fnp-3025	1397	10	.	.	PUNCT
fnp-3025	1398	1	103(30	103(30	NUM
fnp-3025	1398	2	):	):	PUNCT
fnp-3025	1398	3	p.	p.	NOUN
fnp-3025	1398	4	11172	11172	NUM
fnp-3025	1398	5	-	-	SYM
fnp-3025	1398	6	7	7	NUM
fnp-3025	1398	7	.	.	NOUN
fnp-3025	1398	8	199	199	NUM
fnp-3025	1398	9	.	.	PUNCT
fnp-3025	1399	1	takahashi	takahashi	PROPN
fnp-3025	1399	2	,	,	PUNCT
fnp-3025	1399	3	r.h	r.h	PROPN
fnp-3025	1399	4	.	.	PROPN
fnp-3025	1399	5	,	,	PUNCT
fnp-3025	1399	6	et	et	PROPN
fnp-3025	1399	7	al	al	PROPN
fnp-3025	1399	8	.	.	PROPN
fnp-3025	1399	9	,	,	PUNCT
fnp-3025	1399	10	intraneuronal	intraneuronal	PROPN
fnp-3025	1399	11	alzheimer	alzheimer	PROPN
fnp-3025	1399	12	abeta42	abeta42	PROPN
fnp-3025	1399	13	accumulates	accumulate	VERB
fnp-3025	1399	14	in	in	ADP
fnp-3025	1399	15	multivesicular	multivesicular	ADJ
fnp-3025	1399	16	bodies	body	NOUN
fnp-3025	1399	17	and	and	CCONJ
fnp-3025	1399	18	is	be	AUX
fnp-3025	1399	19	associated	associate	VERB
fnp-3025	1399	20	with	with	ADP
fnp-3025	1399	21	synaptic	synaptic	ADJ
fnp-3025	1399	22	pathology	pathology	NOUN
fnp-3025	1399	23	.	.	PUNCT
fnp-3025	1400	1	am	be	AUX
fnp-3025	1400	2	j	j	PROPN
fnp-3025	1400	3	pathol	pathol	NOUN
fnp-3025	1400	4	,	,	PUNCT
fnp-3025	1400	5	2002	2002	NUM
fnp-3025	1400	6	.	.	PUNCT
fnp-3025	1401	1	161(5	161(5	NUM
fnp-3025	1401	2	):	):	PUNCT
fnp-3025	1402	1	p.	p.	NOUN
fnp-3025	1402	2	1869	1869	NUM
fnp-3025	1402	3	-	-	SYM
fnp-3025	1402	4	79	79	NUM
fnp-3025	1402	5	.	.	PUNCT
fnp-3025	1402	6	200	200	NUM
fnp-3025	1402	7	.	.	PUNCT
fnp-3025	1403	1	willen	willen	PROPN
fnp-3025	1403	2	,	,	PUNCT
fnp-3025	1403	3	k.	k.	PROPN
fnp-3025	1403	4	,	,	PUNCT
fnp-3025	1403	5	et	et	PROPN
fnp-3025	1403	6	al	al	PROPN
fnp-3025	1403	7	.	.	PROPN
fnp-3025	1403	8	,	,	PUNCT
fnp-3025	1403	9	abeta	abeta	PROPN
fnp-3025	1403	10	accumulation	accumulation	NOUN
fnp-3025	1403	11	causes	cause	VERB
fnp-3025	1403	12	mvb	mvb	NOUN
fnp-3025	1403	13	enlargement	enlargement	NOUN
fnp-3025	1403	14	and	and	CCONJ
fnp-3025	1403	15	is	be	AUX
fnp-3025	1403	16	modelled	model	VERB
fnp-3025	1403	17	by	by	ADP
fnp-3025	1403	18	dominant	dominant	ADJ
fnp-3025	1403	19	negative	negative	ADJ
fnp-3025	1403	20	vps4a	vps4a	PROPN
fnp-3025	1403	21	.	.	PUNCT
fnp-3025	1404	1	mol	mol	ADP
fnp-3025	1404	2	neurodegener	neurodegener	NOUN
fnp-3025	1404	3	,	,	PUNCT
fnp-3025	1404	4	2017	2017	NUM
fnp-3025	1404	5	.	.	PUNCT
fnp-3025	1405	1	12(1	12(1	NUM
fnp-3025	1405	2	):	):	PUNCT
fnp-3025	1406	1	p.	p.	NOUN
fnp-3025	1406	2	61	61	NUM
fnp-3025	1406	3	.	.	PUNCT
fnp-3025	1406	4	201	201	NUM
fnp-3025	1406	5	.	.	PUNCT
fnp-3025	1407	1	becot	becot	NOUN
fnp-3025	1407	2	,	,	PUNCT
fnp-3025	1407	3	a.	a.	NOUN
fnp-3025	1407	4	,	,	PUNCT
fnp-3025	1407	5	c.	c.	NOUN
fnp-3025	1407	6	volgers	volger	NOUN
fnp-3025	1407	7	,	,	PUNCT
fnp-3025	1407	8	and	and	CCONJ
fnp-3025	1407	9	g.	g.	PROPN
fnp-3025	1407	10	van	van	PROPN
fnp-3025	1407	11	niel	niel	PROPN
fnp-3025	1407	12	,	,	PUNCT
fnp-3025	1407	13	transmissible	transmissible	ADJ
fnp-3025	1407	14	endosomal	endosomal	ADJ
fnp-3025	1407	15	intoxication	intoxication	NOUN
fnp-3025	1407	16	:	:	PUNCT
fnp-3025	1407	17	a	a	DET
fnp-3025	1407	18	balance	balance	NOUN
fnp-3025	1407	19	between	between	ADP
fnp-3025	1407	20	exosomes	exosome	NOUN
fnp-3025	1407	21	and	and	CCONJ
fnp-3025	1407	22	lysosomes	lysosome	NOUN
fnp-3025	1407	23	at	at	ADP
fnp-3025	1407	24	the	the	DET
fnp-3025	1407	25	basis	basis	NOUN
fnp-3025	1407	26	of	of	ADP
fnp-3025	1407	27	intercellular	intercellular	ADJ
fnp-3025	1407	28	amyloid	amyloid	NOUN
fnp-3025	1407	29	propagation	propagation	NOUN
fnp-3025	1407	30	.	.	PUNCT
fnp-3025	1408	1	biomedicines	biomedicine	NOUN
fnp-3025	1408	2	,	,	PUNCT
fnp-3025	1408	3	2020	2020	NUM
fnp-3025	1408	4	.	.	PUNCT
fnp-3025	1409	1	8(8	8(8	NUM
fnp-3025	1409	2	)	)	PUNCT
fnp-3025	1409	3	.	.	PUNCT
fnp-3025	1410	1	202	202	NUM
fnp-3025	1410	2	.	.	PUNCT
fnp-3025	1411	1	han	han	PROPN
fnp-3025	1411	2	,	,	PUNCT
fnp-3025	1411	3	s.	s.	PROPN
fnp-3025	1411	4	,	,	PUNCT
fnp-3025	1411	5	et	et	PROPN
fnp-3025	1411	6	al	al	PROPN
fnp-3025	1411	7	.	.	PROPN
fnp-3025	1411	8	,	,	PUNCT
fnp-3025	1411	9	amyloid	amyloid	NOUN
fnp-3025	1411	10	plaque	plaque	NOUN
fnp-3025	1411	11	structure	structure	NOUN
fnp-3025	1411	12	and	and	CCONJ
fnp-3025	1411	13	cell	cell	NOUN
fnp-3025	1411	14	surface	surface	NOUN
fnp-3025	1411	15	interactions	interaction	NOUN
fnp-3025	1411	16	of	of	ADP
fnp-3025	1411	17	beta	beta	NOUN
fnp-3025	1411	18	-	-	PUNCT
fnp-3025	1411	19	amyloid	amyloid	NOUN
fnp-3025	1411	20	fibrils	fibril	NOUN
fnp-3025	1411	21	revealed	reveal	VERB
fnp-3025	1411	22	by	by	ADP
fnp-3025	1411	23	electron	electron	NOUN
fnp-3025	1411	24	tomography	tomography	NOUN
fnp-3025	1411	25	.	.	PUNCT
fnp-3025	1412	1	sci	sci	PROPN
fnp-3025	1412	2	rep	rep	PROPN
fnp-3025	1412	3	,	,	PUNCT
fnp-3025	1412	4	2017	2017	NUM
fnp-3025	1412	5	.	.	PUNCT
fnp-3025	1413	1	7	7	NUM
fnp-3025	1413	2	:	:	PUNCT
fnp-3025	1413	3	p.	p.	NOUN
fnp-3025	1413	4	43577	43577	NUM
fnp-3025	1413	5	.	.	PUNCT
fnp-3025	1414	1	203	203	NUM
fnp-3025	1414	2	.	.	PUNCT
fnp-3025	1415	1	schmidt	schmidt	PROPN
fnp-3025	1415	2	,	,	PUNCT
fnp-3025	1415	3	m.l	m.l	PROPN
fnp-3025	1415	4	.	.	PROPN
fnp-3025	1415	5	,	,	PUNCT
fnp-3025	1415	6	et	et	PROPN
fnp-3025	1415	7	al	al	PROPN
fnp-3025	1415	8	.	.	PROPN
fnp-3025	1415	9	,	,	PUNCT
fnp-3025	1415	10	chemical	chemical	NOUN
fnp-3025	1415	11	and	and	CCONJ
fnp-3025	1415	12	immunological	immunological	ADJ
fnp-3025	1415	13	heterogeneity	heterogeneity	NOUN
fnp-3025	1415	14	of	of	ADP
fnp-3025	1415	15	fibrillar	fibrillar	ADJ
fnp-3025	1415	16	amyloid	amyloid	NOUN
fnp-3025	1415	17	in	in	ADP
fnp-3025	1415	18	plaques	plaque	NOUN
fnp-3025	1415	19	of	of	ADP
fnp-3025	1415	20	alzheimer	alzheimer	PROPN
fnp-3025	1415	21	’s	’s	PART
fnp-3025	1415	22	disease	disease	NOUN
fnp-3025	1415	23	and	and	CCONJ
fnp-3025	1415	24	down	down	ADP
fnp-3025	1415	25	’s	’s	PART
fnp-3025	1415	26	syndrome	syndrome	NOUN
fnp-3025	1415	27	brains	brain	NOUN
fnp-3025	1415	28	revealed	reveal	VERB
fnp-3025	1415	29	by	by	ADP
fnp-3025	1415	30	confocal	confocal	ADJ
fnp-3025	1415	31	microscopy	microscopy	NOUN
fnp-3025	1415	32	.	.	PUNCT
fnp-3025	1416	1	am	be	AUX
fnp-3025	1416	2	j	j	PROPN
fnp-3025	1416	3	pathol	pathol	NOUN
fnp-3025	1416	4	,	,	PUNCT
fnp-3025	1416	5	1995	1995	NUM
fnp-3025	1416	6	.	.	PUNCT
fnp-3025	1417	1	147(2	147(2	NUM
fnp-3025	1417	2	):	):	PUNCT
fnp-3025	1417	3	p.	p.	NOUN
fnp-3025	1417	4	503	503	NUM
fnp-3025	1417	5	-	-	SYM
fnp-3025	1417	6	15	15	NUM
fnp-3025	1417	7	.	.	PUNCT
fnp-3025	1418	1	204	204	NUM
fnp-3025	1418	2	.	.	PUNCT
fnp-3025	1419	1	nelson	nelson	PROPN
fnp-3025	1419	2	,	,	PUNCT
fnp-3025	1419	3	p.t	p.t	PROPN
fnp-3025	1419	4	.	.	PROPN
fnp-3025	1419	5	,	,	PUNCT
fnp-3025	1419	6	h.	h.	PROPN
fnp-3025	1419	7	braak	braak	PROPN
fnp-3025	1419	8	,	,	PUNCT
fnp-3025	1419	9	and	and	CCONJ
fnp-3025	1419	10	w.r	w.r	PROPN
fnp-3025	1419	11	.	.	PROPN
fnp-3025	1419	12	markesbery	markesbery	PROPN
fnp-3025	1419	13	,	,	PUNCT
fnp-3025	1419	14	neuropathology	neuropathology	NOUN
fnp-3025	1419	15	and	and	CCONJ
fnp-3025	1419	16	cognitive	cognitive	ADJ
fnp-3025	1419	17	impairment	impairment	NOUN
fnp-3025	1419	18	in	in	ADP
fnp-3025	1419	19	alzheimer	alzheimer	PROPN
fnp-3025	1419	20	disease	disease	PROPN
fnp-3025	1419	21	:	:	PUNCT
fnp-3025	1419	22	a	a	DET
fnp-3025	1419	23	complex	complex	ADJ
fnp-3025	1419	24	but	but	CCONJ
fnp-3025	1419	25	coherent	coherent	ADJ
fnp-3025	1419	26	relationship	relationship	NOUN
fnp-3025	1419	27	.	.	PUNCT
fnp-3025	1420	1	j	j	PROPN
fnp-3025	1420	2	neuropathol	neuropathol	PROPN
fnp-3025	1420	3	exp	exp	PROPN
fnp-3025	1420	4	neurol	neurol	PROPN
fnp-3025	1420	5	,	,	PUNCT
fnp-3025	1420	6	2009	2009	NUM
fnp-3025	1420	7	.	.	PUNCT
fnp-3025	1421	1	68(1	68(1	NOUN
fnp-3025	1421	2	):	):	PUNCT
fnp-3025	1421	3	p.	p.	NOUN
fnp-3025	1421	4	1	1	NUM
fnp-3025	1421	5	-	-	SYM
fnp-3025	1421	6	14	14	NUM
fnp-3025	1421	7	.	.	PUNCT
fnp-3025	1422	1	205	205	NUM
fnp-3025	1422	2	.	.	PUNCT
fnp-3025	1423	1	prusiner	prusiner	NOUN
fnp-3025	1423	2	,	,	PUNCT
fnp-3025	1423	3	s.b	s.b	PROPN
fnp-3025	1423	4	.	.	PROPN
fnp-3025	1423	5	,	,	PUNCT
fnp-3025	1423	6	an	an	DET
fnp-3025	1423	7	introduction	introduction	NOUN
fnp-3025	1423	8	to	to	ADP
fnp-3025	1423	9	prion	prion	NOUN
fnp-3025	1423	10	diseases	disease	NOUN
fnp-3025	1423	11	,	,	PUNCT
fnp-3025	1423	12	in	in	ADP
fnp-3025	1423	13	prion	prion	NOUN
fnp-3025	1423	14	diseases	disease	NOUN
fnp-3025	1423	15	,	,	PUNCT
fnp-3025	1423	16	s.b	s.b	PROPN
fnp-3025	1423	17	.	.	PROPN
fnp-3025	1423	18	prusiner	prusiner	NOUN
fnp-3025	1423	19	,	,	PUNCT
fnp-3025	1423	20	editor	editor	NOUN
fnp-3025	1423	21	.	.	PUNCT
fnp-3025	1424	1	2017	2017	NUM
fnp-3025	1424	2	,	,	PUNCT
fnp-3025	1424	3	cold	cold	ADJ
fnp-3025	1424	4	spring	spring	NOUN
fnp-3025	1424	5	harbor	harbor	NOUN
fnp-3025	1424	6	laboratory	laboratory	PROPN
fnp-3025	1424	7	press	press	PROPN
fnp-3025	1424	8	:	:	PUNCT
fnp-3025	1424	9	cold	cold	ADJ
fnp-3025	1424	10	spring	spring	NOUN
fnp-3025	1424	11	harbor	harbor	NOUN
fnp-3025	1424	12	p.	p.	NOUN
fnp-3025	1424	13	1	1	NUM
fnp-3025	1424	14	-	-	SYM
fnp-3025	1424	15	29	29	NUM
fnp-3025	1424	16	.	.	PUNCT
fnp-3025	1425	1	206	206	NUM
fnp-3025	1425	2	.	.	PUNCT
fnp-3025	1426	1	will	will	AUX
fnp-3025	1426	2	,	,	PUNCT
fnp-3025	1426	3	r.g	r.g	PROPN
fnp-3025	1426	4	.	.	PROPN
fnp-3025	1426	5	and	and	CCONJ
fnp-3025	1426	6	j.w	j.w	PROPN
fnp-3025	1426	7	.	.	PROPN
fnp-3025	1426	8	ironside	ironside	PROPN
fnp-3025	1426	9	,	,	PUNCT
fnp-3025	1426	10	sporadic	sporadic	ADJ
fnp-3025	1426	11	and	and	CCONJ
fnp-3025	1426	12	infectious	infectious	ADJ
fnp-3025	1426	13	human	human	ADJ
fnp-3025	1426	14	prion	prion	NOUN
fnp-3025	1426	15	diseases	disease	NOUN
fnp-3025	1426	16	.	.	PUNCT
fnp-3025	1427	1	cold	cold	ADJ
fnp-3025	1427	2	spring	spring	NOUN
fnp-3025	1427	3	harb	harb	PROPN
fnp-3025	1427	4	perspect	perspect	PROPN
fnp-3025	1427	5	med	me	VERB
fnp-3025	1427	6	,	,	PUNCT
fnp-3025	1427	7	2017	2017	NUM
fnp-3025	1427	8	.	.	PUNCT
fnp-3025	1428	1	7(1	7(1	NUM
fnp-3025	1428	2	):	):	PUNCT
fnp-3025	1428	3	p.	p.	NOUN
fnp-3025	1428	4	a024364	a024364	PROPN
fnp-3025	1428	5	.	.	PUNCT
fnp-3025	1429	1	207	207	NUM
fnp-3025	1429	2	.	.	PUNCT
fnp-3025	1430	1	fiala	fiala	PROPN
fnp-3025	1430	2	,	,	PUNCT
fnp-3025	1430	3	j.c	j.c	PROPN
fnp-3025	1430	4	.	.	PROPN
fnp-3025	1430	5	,	,	PUNCT
fnp-3025	1430	6	mechanisms	mechanism	NOUN
fnp-3025	1430	7	of	of	ADP
fnp-3025	1430	8	amyloid	amyloid	NOUN
fnp-3025	1430	9	plaque	plaque	NOUN
fnp-3025	1430	10	pathogenesis	pathogenesis	NOUN
fnp-3025	1430	11	.	.	PUNCT
fnp-3025	1431	1	acta	acta	PROPN
fnp-3025	1431	2	neuropathol	neuropathol	PROPN
fnp-3025	1431	3	,	,	PUNCT
fnp-3025	1431	4	2007	2007	NUM
fnp-3025	1431	5	.	.	PUNCT
fnp-3025	1432	1	114(6	114(6	NUM
fnp-3025	1432	2	):	):	PUNCT
fnp-3025	1433	1	p.	p.	NOUN
fnp-3025	1433	2	551	551	NUM
fnp-3025	1433	3	-	-	SYM
fnp-3025	1433	4	71	71	NUM
fnp-3025	1433	5	.	.	PUNCT
fnp-3025	1433	6	208	208	NUM
fnp-3025	1433	7	.	.	X
fnp-3025	1434	1	azizeh	azizeh	PROPN
fnp-3025	1434	2	,	,	PUNCT
fnp-3025	1434	3	b.y	b.y	PROPN
fnp-3025	1434	4	.	.	PROPN
fnp-3025	1434	5	,	,	PUNCT
fnp-3025	1434	6	et	et	PROPN
fnp-3025	1434	7	al	al	PROPN
fnp-3025	1434	8	.	.	PROPN
fnp-3025	1434	9	,	,	PUNCT
fnp-3025	1434	10	molecular	molecular	ADJ
fnp-3025	1434	11	dating	date	VERB
fnp-3025	1434	12	of	of	ADP
fnp-3025	1434	13	senile	senile	ADJ
fnp-3025	1434	14	plaques	plaque	NOUN
fnp-3025	1434	15	in	in	ADP
fnp-3025	1434	16	the	the	DET
fnp-3025	1434	17	brains	brain	NOUN
fnp-3025	1434	18	of	of	ADP
fnp-3025	1434	19	individuals	individual	NOUN
fnp-3025	1434	20	with	with	ADP
fnp-3025	1434	21	down	down	ADP
fnp-3025	1434	22	syndrome	syndrome	NOUN
fnp-3025	1434	23	and	and	CCONJ
fnp-3025	1434	24	in	in	ADP
fnp-3025	1434	25	aged	aged	ADJ
fnp-3025	1434	26	dogs	dog	NOUN
fnp-3025	1434	27	.	.	PUNCT
fnp-3025	1435	1	exp	exp	NOUN
fnp-3025	1435	2	neurol	neurol	NOUN
fnp-3025	1435	3	,	,	PUNCT
fnp-3025	1435	4	2000	2000	NUM
fnp-3025	1435	5	.	.	PUNCT
fnp-3025	1436	1	163(1	163(1	NUM
fnp-3025	1436	2	):	):	PUNCT
fnp-3025	1436	3	p.	p.	NOUN
fnp-3025	1436	4	111	111	NUM
fnp-3025	1436	5	-	-	SYM
fnp-3025	1436	6	22	22	NUM
fnp-3025	1436	7	.	.	PUNCT
fnp-3025	1437	1	209	209	NUM
fnp-3025	1437	2	.	.	PUNCT
fnp-3025	1438	1	fonseca	fonseca	PROPN
fnp-3025	1438	2	,	,	PUNCT
fnp-3025	1438	3	m.i	m.i	PROPN
fnp-3025	1438	4	.	.	PROPN
fnp-3025	1438	5	,	,	PUNCT
fnp-3025	1438	6	et	et	PROPN
fnp-3025	1438	7	al	al	PROPN
fnp-3025	1438	8	.	.	PROPN
fnp-3025	1438	9	,	,	PUNCT
fnp-3025	1438	10	the	the	DET
fnp-3025	1438	11	presence	presence	NOUN
fnp-3025	1438	12	of	of	ADP
fnp-3025	1438	13	isoaspartic	isoaspartic	ADJ
fnp-3025	1438	14	acid	acid	NOUN
fnp-3025	1438	15	in	in	ADP
fnp-3025	1438	16	beta	beta	NOUN
fnp-3025	1438	17	-	-	PUNCT
fnp-3025	1438	18	amyloid	amyloid	NOUN
fnp-3025	1438	19	plaques	plaque	NOUN
fnp-3025	1438	20	indicates	indicate	VERB
fnp-3025	1438	21	plaque	plaque	NOUN
fnp-3025	1438	22	age	age	NOUN
fnp-3025	1438	23	.	.	PUNCT
fnp-3025	1439	1	exp	exp	NOUN
fnp-3025	1439	2	neurol	neurol	NOUN
fnp-3025	1439	3	,	,	PUNCT
fnp-3025	1439	4	1999	1999	NUM
fnp-3025	1439	5	.	.	PUNCT
fnp-3025	1440	1	157(2	157(2	NUM
fnp-3025	1440	2	):	):	PUNCT
fnp-3025	1441	1	p.	p.	NOUN
fnp-3025	1441	2	277	277	NUM
fnp-3025	1441	3	-	-	SYM
fnp-3025	1441	4	88	88	NUM
fnp-3025	1441	5	.	.	PUNCT
fnp-3025	1441	6	210	210	NUM
fnp-3025	1441	7	.	.	PUNCT
fnp-3025	1442	1	lee	lee	PROPN
fnp-3025	1442	2	,	,	PUNCT
fnp-3025	1442	3	h.g	h.g	PROPN
fnp-3025	1442	4	.	.	PROPN
fnp-3025	1442	5	,	,	PUNCT
fnp-3025	1442	6	et	et	PROPN
fnp-3025	1442	7	al	al	PROPN
fnp-3025	1442	8	.	.	PROPN
fnp-3025	1442	9	,	,	PUNCT
fnp-3025	1442	10	challenging	challenge	VERB
fnp-3025	1442	11	the	the	DET
fnp-3025	1442	12	amyloid	amyloid	NOUN
fnp-3025	1442	13	cascade	cascade	NOUN
fnp-3025	1442	14	hypothesis	hypothesis	NOUN
fnp-3025	1442	15	:	:	PUNCT
fnp-3025	1442	16	senile	senile	ADJ
fnp-3025	1442	17	plaques	plaque	NOUN
fnp-3025	1442	18	and	and	CCONJ
fnp-3025	1442	19	amyloid	amyloid	NOUN
fnp-3025	1442	20	-	-	PUNCT
fnp-3025	1442	21	beta	beta	NOUN
fnp-3025	1442	22	as	as	ADP
fnp-3025	1442	23	protective	protective	ADJ
fnp-3025	1442	24	adaptations	adaptation	NOUN
fnp-3025	1442	25	to	to	ADP
fnp-3025	1442	26	alzheimer	alzheimer	PROPN
fnp-3025	1442	27	disease	disease	PROPN
fnp-3025	1442	28	.	.	PUNCT
fnp-3025	1443	1	ann	ann	PROPN
fnp-3025	1443	2	n	n	PROPN
fnp-3025	1443	3	y	y	PROPN
fnp-3025	1443	4	acad	acad	PROPN
fnp-3025	1443	5	sci	sci	PROPN
fnp-3025	1443	6	,	,	PUNCT
fnp-3025	1443	7	2004	2004	NUM
fnp-3025	1443	8	.	.	PUNCT
fnp-3025	1444	1	1019	1019	NUM
fnp-3025	1444	2	:	:	PUNCT
fnp-3025	1445	1	p.	p.	NOUN
fnp-3025	1445	2	1	1	NUM
fnp-3025	1445	3	-	-	SYM
fnp-3025	1445	4	4	4	NUM
fnp-3025	1445	5	.	.	NOUN
fnp-3025	1445	6	211	211	NUM
fnp-3025	1445	7	.	.	PUNCT
fnp-3025	1446	1	makin	makin	PROPN
fnp-3025	1446	2	,	,	PUNCT
fnp-3025	1446	3	s.	s.	PROPN
fnp-3025	1446	4	,	,	PUNCT
fnp-3025	1446	5	the	the	DET
fnp-3025	1446	6	amyloid	amyloid	NOUN
fnp-3025	1446	7	hypothesis	hypothesis	NOUN
fnp-3025	1446	8	on	on	ADP
fnp-3025	1446	9	trial	trial	NOUN
fnp-3025	1446	10	.	.	PUNCT
fnp-3025	1447	1	nature	nature	NOUN
fnp-3025	1447	2	,	,	PUNCT
fnp-3025	1447	3	2018	2018	NUM
fnp-3025	1447	4	.	.	PUNCT
fnp-3025	1448	1	559(7715	559(7715	NOUN
fnp-3025	1448	2	):	):	PUNCT
fnp-3025	1448	3	p.	p.	NOUN
fnp-3025	1448	4	s4	s4	NOUN
fnp-3025	1448	5	-	-	PUNCT
fnp-3025	1448	6	s7	s7	NOUN
fnp-3025	1448	7	.	.	PUNCT
fnp-3025	1449	1	212	212	NUM
fnp-3025	1449	2	.	.	PUNCT
fnp-3025	1449	3	walker	walker	PROPN
fnp-3025	1449	4	,	,	PUNCT
fnp-3025	1449	5	l.c	l.c	PROPN
fnp-3025	1449	6	.	.	PROPN
fnp-3025	1449	7	,	,	PUNCT
fnp-3025	1449	8	proteopathic	proteopathic	ADJ
fnp-3025	1449	9	strains	strain	NOUN
fnp-3025	1449	10	and	and	CCONJ
fnp-3025	1449	11	the	the	DET
fnp-3025	1449	12	heterogeneity	heterogeneity	NOUN
fnp-3025	1449	13	of	of	ADP
fnp-3025	1449	14	neurodegenerative	neurodegenerative	ADJ
fnp-3025	1449	15	diseases	disease	NOUN
fnp-3025	1449	16	.	.	PUNCT
fnp-3025	1450	1	annu	annu	PROPN
fnp-3025	1450	2	rev	rev	PROPN
fnp-3025	1450	3	genet	genet	PROPN
fnp-3025	1450	4	,	,	PUNCT
fnp-3025	1450	5	2016	2016	NUM
fnp-3025	1450	6	.	.	PUNCT
fnp-3025	1451	1	50	50	NUM
fnp-3025	1451	2	:	:	PUNCT
fnp-3025	1451	3	p.	p.	NOUN
fnp-3025	1451	4	329	329	NUM
fnp-3025	1451	5	-	-	SYM
fnp-3025	1451	6	346	346	NUM
fnp-3025	1451	7	.	.	PUNCT
fnp-3025	1451	8	213	213	NUM
fnp-3025	1451	9	.	.	PUNCT
fnp-3025	1452	1	lau	lau	PROPN
fnp-3025	1452	2	,	,	PUNCT
fnp-3025	1452	3	h.h.c	h.h.c	PROPN
fnp-3025	1452	4	.	.	PROPN
fnp-3025	1452	5	,	,	PUNCT
fnp-3025	1452	6	m.	m.	NOUN
fnp-3025	1452	7	ingelsson	ingelsson	PROPN
fnp-3025	1452	8	,	,	PUNCT
fnp-3025	1452	9	and	and	CCONJ
fnp-3025	1452	10	j.c	j.c	PROPN
fnp-3025	1452	11	.	.	PROPN
fnp-3025	1452	12	watts	watts	PROPN
fnp-3025	1452	13	,	,	PUNCT
fnp-3025	1452	14	the	the	DET
fnp-3025	1452	15	existence	existence	NOUN
fnp-3025	1452	16	of	of	ADP
fnp-3025	1452	17	abeta	abeta	PROPN
fnp-3025	1452	18	strains	strain	NOUN
fnp-3025	1452	19	and	and	CCONJ
fnp-3025	1452	20	their	their	PRON
fnp-3025	1452	21	potential	potential	NOUN
fnp-3025	1452	22	for	for	ADP
fnp-3025	1452	23	driving	drive	VERB
fnp-3025	1452	24	phenotypic	phenotypic	ADJ
fnp-3025	1452	25	heterogeneity	heterogeneity	NOUN
fnp-3025	1452	26	in	in	ADP
fnp-3025	1452	27	alzheimer	alzheimer	PROPN
fnp-3025	1452	28	’s	’s	PART
fnp-3025	1452	29	disease	disease	NOUN
fnp-3025	1452	30	.	.	PUNCT
fnp-3025	1453	1	acta	acta	PROPN
fnp-3025	1453	2	neuropathol	neuropathol	PROPN
fnp-3025	1453	3	,	,	PUNCT
fnp-3025	1453	4	2020	2020	NUM
fnp-3025	1453	5	.	.	PUNCT
fnp-3025	1454	1	doi	doi	NOUN
fnp-3025	1454	2	:	:	PUNCT
fnp-3025	1454	3	10.1007	10.1007	NUM
fnp-3025	1454	4	/	/	SYM
fnp-3025	1454	5	s00401	s00401	NOUN
fnp-3025	1454	6	-	-	PUNCT
fnp-3025	1454	7	020	020	NUM
fnp-3025	1454	8	-	-	PUNCT
fnp-3025	1454	9	02201	02201	NUM
fnp-3025	1454	10	-	-	SYM
fnp-3025	1454	11	2	2	NUM
fnp-3025	1454	12	.	.	PUNCT
fnp-3025	1455	1	online	online	ADV
fnp-3025	1455	2	ahead	ahead	ADV
fnp-3025	1455	3	of	of	ADP
fnp-3025	1455	4	print	print	NOUN
fnp-3025	1455	5	.	.	PUNCT
fnp-3025	1456	1	pmid	pmid	NOUN
fnp-3025	1456	2	:	:	PUNCT
fnp-3025	1456	3	32743745	32743745	NUM
fnp-3025	1456	4	.	.	PUNCT
fnp-3025	1457	1	214	214	NUM
fnp-3025	1457	2	.	.	PUNCT
fnp-3025	1457	3	bartz	bartz	PROPN
fnp-3025	1457	4	,	,	PUNCT
fnp-3025	1457	5	j.c	j.c	PROPN
fnp-3025	1457	6	.	.	PROPN
fnp-3025	1457	7	,	,	PUNCT
fnp-3025	1457	8	prion	prion	NOUN
fnp-3025	1457	9	strain	strain	NOUN
fnp-3025	1457	10	diversity	diversity	NOUN
fnp-3025	1457	11	.	.	PUNCT
fnp-3025	1458	1	cold	cold	ADJ
fnp-3025	1458	2	spring	spring	NOUN
fnp-3025	1458	3	harb	harb	PROPN
fnp-3025	1458	4	perspect	perspect	PROPN
fnp-3025	1458	5	med	med	PROPN
fnp-3025	1458	6	,	,	PUNCT
fnp-3025	1458	7	2016	2016	NUM
fnp-3025	1458	8	.	.	PUNCT
fnp-3025	1459	1	6(12	6(12	NUM
fnp-3025	1459	2	):	):	PUNCT
fnp-3025	1459	3	p.	p.	NOUN
fnp-3025	1459	4	a024349	a024349	NOUN
fnp-3025	1459	5	.	.	PROPN
fnp-3025	1460	1	215	215	NUM
fnp-3025	1460	2	.	.	PUNCT
fnp-3025	1461	1	ghaemmaghami	ghaemmaghami	ADJ
fnp-3025	1461	2	,	,	PUNCT
fnp-3025	1461	3	s.	s.	PROPN
fnp-3025	1461	4	,	,	PUNCT
fnp-3025	1461	5	biology	biology	NOUN
fnp-3025	1461	6	and	and	CCONJ
fnp-3025	1461	7	genetics	genetic	NOUN
fnp-3025	1461	8	of	of	ADP
fnp-3025	1461	9	prp	prp	PROPN
fnp-3025	1461	10	prion	prion	NOUN
fnp-3025	1461	11	strains	strain	VERB
fnp-3025	1461	12	.	.	PUNCT
fnp-3025	1462	1	cold	cold	ADJ
fnp-3025	1462	2	spring	spring	NOUN
fnp-3025	1462	3	harb	harb	PROPN
fnp-3025	1462	4	perspect	perspect	PROPN
fnp-3025	1462	5	med	me	VERB
fnp-3025	1462	6	,	,	PUNCT
fnp-3025	1462	7	2017	2017	NUM
fnp-3025	1462	8	.	.	PUNCT
fnp-3025	1463	1	7(8	7(8	NUM
fnp-3025	1463	2	):	):	PUNCT
fnp-3025	1463	3	p.	p.	NOUN
fnp-3025	1463	4	a026922	a026922	NOUN
fnp-3025	1463	5	.	.	PROPN
fnp-3025	1463	6	216	216	NUM
fnp-3025	1463	7	.	.	PUNCT
fnp-3025	1464	1	prusiner	prusiner	NOUN
fnp-3025	1464	2	,	,	PUNCT
fnp-3025	1464	3	s.b	s.b	PROPN
fnp-3025	1464	4	.	.	PROPN
fnp-3025	1464	5	,	,	PUNCT
fnp-3025	1464	6	prion	prion	NOUN
fnp-3025	1464	7	diseases	disease	NOUN
fnp-3025	1464	8	.	.	PUNCT
fnp-3025	1465	1	2017	2017	NUM
fnp-3025	1465	2	,	,	PUNCT
fnp-3025	1465	3	cold	cold	ADJ
fnp-3025	1465	4	spring	spring	NOUN
fnp-3025	1465	5	harbor	harbor	NOUN
fnp-3025	1465	6	:	:	PUNCT
fnp-3025	1465	7	cold	cold	ADJ
fnp-3025	1465	8	spring	spring	NOUN
fnp-3025	1465	9	harbor	harbor	PROPN
fnp-3025	1465	10	laboratory	laboratory	PROPN
fnp-3025	1465	11	press	press	NOUN
fnp-3025	1465	12	.	.	PUNCT
fnp-3025	1466	1	217	217	NUM
fnp-3025	1466	2	.	.	PUNCT
fnp-3025	1467	1	jucker	jucker	PROPN
fnp-3025	1467	2	,	,	PUNCT
fnp-3025	1467	3	m.	m.	NOUN
fnp-3025	1467	4	and	and	CCONJ
fnp-3025	1467	5	l.c	l.c	PROPN
fnp-3025	1467	6	.	.	PROPN
fnp-3025	1467	7	walker	walker	PROPN
fnp-3025	1467	8	,	,	PUNCT
fnp-3025	1467	9	self	self	NOUN
fnp-3025	1467	10	-	-	PUNCT
fnp-3025	1467	11	propagation	propagation	NOUN
fnp-3025	1467	12	of	of	ADP
fnp-3025	1467	13	pathogenic	pathogenic	ADJ
fnp-3025	1467	14	protein	protein	NOUN
fnp-3025	1467	15	aggregates	aggregate	NOUN
fnp-3025	1467	16	in	in	ADP
fnp-3025	1467	17	neurodegenerative	neurodegenerative	ADJ
fnp-3025	1467	18	diseases	disease	NOUN
fnp-3025	1467	19	.	.	PUNCT
fnp-3025	1468	1	nature	nature	NOUN
fnp-3025	1468	2	,	,	PUNCT
fnp-3025	1468	3	2013	2013	NUM
fnp-3025	1468	4	.	.	PUNCT
fnp-3025	1469	1	501(7465	501(7465	NUM
fnp-3025	1469	2	):	):	PUNCT
fnp-3025	1469	3	p.	p.	NOUN
fnp-3025	1469	4	45	45	NUM
fnp-3025	1469	5	-	-	SYM
fnp-3025	1469	6	51	51	NUM
fnp-3025	1469	7	.	.	PUNCT
fnp-3025	1469	8	218	218	NUM
fnp-3025	1469	9	.	.	PUNCT
fnp-3025	1470	1	walker	walker	PROPN
fnp-3025	1470	2	,	,	PUNCT
fnp-3025	1470	3	l.c	l.c	PROPN
fnp-3025	1470	4	.	.	PROPN
fnp-3025	1470	5	and	and	CCONJ
fnp-3025	1470	6	m.	m.	PROPN
fnp-3025	1470	7	jucker	jucker	PROPN
fnp-3025	1470	8	,	,	PUNCT
fnp-3025	1470	9	neurodegenerative	neurodegenerative	ADJ
fnp-3025	1470	10	diseases	disease	NOUN
fnp-3025	1470	11	:	:	PUNCT
fnp-3025	1470	12	expanding	expand	VERB
fnp-3025	1470	13	the	the	DET
fnp-3025	1470	14	prion	prion	NOUN
fnp-3025	1470	15	concept	concept	NOUN
fnp-3025	1470	16	.	.	PUNCT
fnp-3025	1471	1	annu	annu	PROPN
fnp-3025	1471	2	rev	rev	PROPN
fnp-3025	1471	3	neurosci	neurosci	PROPN
fnp-3025	1471	4	,	,	PUNCT
fnp-3025	1471	5	2015	2015	NUM
fnp-3025	1471	6	.	.	PUNCT
fnp-3025	1472	1	38	38	NUM
fnp-3025	1472	2	:	:	PUNCT
fnp-3025	1472	3	p.	p.	NOUN
fnp-3025	1472	4	87	87	NUM
fnp-3025	1472	5	-	-	SYM
fnp-3025	1472	6	103	103	NUM
fnp-3025	1472	7	.	.	PUNCT
fnp-3025	1472	8	219	219	NUM
fnp-3025	1472	9	.	.	PUNCT
fnp-3025	1473	1	tanaka	tanaka	PROPN
fnp-3025	1473	2	,	,	PUNCT
fnp-3025	1473	3	m.	m.	NOUN
fnp-3025	1473	4	,	,	PUNCT
fnp-3025	1473	5	et	et	PROPN
fnp-3025	1473	6	al	al	PROPN
fnp-3025	1473	7	.	.	PROPN
fnp-3025	1473	8	,	,	PUNCT
fnp-3025	1473	9	the	the	DET
fnp-3025	1473	10	physical	physical	ADJ
fnp-3025	1473	11	basis	basis	NOUN
fnp-3025	1473	12	of	of	ADP
fnp-3025	1473	13	how	how	SCONJ
fnp-3025	1473	14	prion	prion	NOUN
fnp-3025	1473	15	conformations	conformation	NOUN
fnp-3025	1473	16	determine	determine	VERB
fnp-3025	1473	17	strain	strain	NOUN
fnp-3025	1473	18	phenotypes	phenotype	NOUN
fnp-3025	1473	19	.	.	PUNCT
fnp-3025	1474	1	nature	nature	NOUN
fnp-3025	1474	2	,	,	PUNCT
fnp-3025	1474	3	2006	2006	NUM
fnp-3025	1474	4	.	.	PUNCT
fnp-3025	1475	1	442(7102	442(7102	NUM
fnp-3025	1475	2	):	):	PUNCT
fnp-3025	1475	3	p.	p.	NOUN
fnp-3025	1475	4	585	585	NUM
fnp-3025	1475	5	-	-	SYM
fnp-3025	1475	6	9	9	NUM
fnp-3025	1475	7	.	.	NOUN
fnp-3025	1475	8	220	220	NUM
fnp-3025	1475	9	.	.	PUNCT
fnp-3025	1475	10	pedersen	pedersen	PROPN
fnp-3025	1475	11	,	,	PUNCT
fnp-3025	1475	12	j.s	j.s	PROPN
fnp-3025	1475	13	.	.	PROPN
fnp-3025	1475	14	and	and	CCONJ
fnp-3025	1475	15	d.e	d.e	PROPN
fnp-3025	1475	16	.	.	PROPN
fnp-3025	1475	17	otzen	otzen	PROPN
fnp-3025	1475	18	,	,	PUNCT
fnp-3025	1475	19	amyloid	amyloid	NOUN
fnp-3025	1475	20	-	-	PUNCT
fnp-3025	1475	21	a	a	DET
fnp-3025	1475	22	state	state	NOUN
fnp-3025	1475	23	in	in	ADP
fnp-3025	1475	24	many	many	ADJ
fnp-3025	1475	25	guises	guise	NOUN
fnp-3025	1475	26	:	:	PUNCT
fnp-3025	1475	27	survival	survival	NOUN
fnp-3025	1475	28	of	of	ADP
fnp-3025	1475	29	the	the	DET
fnp-3025	1475	30	fittest	fit	ADJ
fnp-3025	1475	31	fibril	fibril	ADJ
fnp-3025	1475	32	fold	fold	NOUN
fnp-3025	1475	33	.	.	PUNCT
fnp-3025	1476	1	protein	protein	NOUN
fnp-3025	1476	2	sci	sci	PROPN
fnp-3025	1476	3	,	,	PUNCT
fnp-3025	1476	4	2008	2008	NUM
fnp-3025	1476	5	.	.	PUNCT
fnp-3025	1477	1	17(1	17(1	NUM
fnp-3025	1477	2	):	):	PUNCT
fnp-3025	1477	3	p.	p.	NOUN
fnp-3025	1477	4	2	2	NUM
fnp-3025	1477	5	-	-	SYM
fnp-3025	1477	6	10	10	NUM
fnp-3025	1477	7	.	.	PUNCT
fnp-3025	1478	1	221	221	NUM
fnp-3025	1478	2	.	.	PUNCT
fnp-3025	1479	1	yagi	yagi	PROPN
fnp-3025	1479	2	,	,	PUNCT
fnp-3025	1479	3	h.	h.	PROPN
fnp-3025	1479	4	,	,	PUNCT
fnp-3025	1479	5	et	et	PROPN
fnp-3025	1479	6	al	al	PROPN
fnp-3025	1479	7	.	.	PROPN
fnp-3025	1479	8	,	,	PUNCT
fnp-3025	1479	9	visualization	visualization	NOUN
fnp-3025	1479	10	and	and	CCONJ
fnp-3025	1479	11	classification	classification	NOUN
fnp-3025	1479	12	of	of	ADP
fnp-3025	1479	13	amyloid	amyloid	NOUN
fnp-3025	1479	14	beta	beta	ADJ
fnp-3025	1479	15	supramolecular	supramolecular	ADJ
fnp-3025	1479	16	assemblies	assembly	NOUN
fnp-3025	1479	17	.	.	PUNCT
fnp-3025	1480	1	biochemistry	biochemistry	NOUN
fnp-3025	1480	2	,	,	PUNCT
fnp-3025	1480	3	2007	2007	NUM
fnp-3025	1480	4	.	.	PUNCT
fnp-3025	1481	1	46(51	46(51	NUM
fnp-3025	1481	2	):	):	PUNCT
fnp-3025	1481	3	p.	p.	NOUN
fnp-3025	1481	4	15009	15009	NUM
fnp-3025	1481	5	-	-	SYM
fnp-3025	1481	6	17	17	NUM
fnp-3025	1481	7	.	.	PUNCT
fnp-3025	1482	1	222	222	NUM
fnp-3025	1482	2	.	.	PUNCT
fnp-3025	1483	1	mehta	mehta	PROPN
fnp-3025	1483	2	,	,	PUNCT
fnp-3025	1483	3	a.k	a.k	PROPN
fnp-3025	1483	4	.	.	PROPN
fnp-3025	1483	5	,	,	PUNCT
fnp-3025	1483	6	et	et	PROPN
fnp-3025	1483	7	al	al	PROPN
fnp-3025	1483	8	.	.	PROPN
fnp-3025	1483	9	,	,	PUNCT
fnp-3025	1483	10	context	context	NOUN
fnp-3025	1483	11	dependence	dependence	NOUN
fnp-3025	1483	12	of	of	ADP
fnp-3025	1483	13	protein	protein	NOUN
fnp-3025	1483	14	misfolding	misfolde	VERB
fnp-3025	1483	15	and	and	CCONJ
fnp-3025	1483	16	structural	structural	ADJ
fnp-3025	1483	17	strains	strain	NOUN
fnp-3025	1483	18	in	in	ADP
fnp-3025	1483	19	neurodegenerative	neurodegenerative	ADJ
fnp-3025	1483	20	diseases	disease	NOUN
fnp-3025	1483	21	.	.	PUNCT
fnp-3025	1484	1	biopolymers	biopolymer	NOUN
fnp-3025	1484	2	,	,	PUNCT
fnp-3025	1484	3	2013	2013	NUM
fnp-3025	1484	4	.	.	PUNCT
fnp-3025	1485	1	100(6	100(6	NUM
fnp-3025	1485	2	):	):	PUNCT
fnp-3025	1485	3	p.	p.	NOUN
fnp-3025	1485	4	722	722	NUM
fnp-3025	1485	5	-	-	SYM
fnp-3025	1485	6	30	30	NUM
fnp-3025	1485	7	.	.	PUNCT
fnp-3025	1485	8	223	223	NUM
fnp-3025	1485	9	.	.	PUNCT
fnp-3025	1486	1	li	li	PROPN
fnp-3025	1486	2	,	,	PUNCT
fnp-3025	1486	3	j.	j.	PROPN
fnp-3025	1486	4	,	,	PUNCT
fnp-3025	1486	5	et	et	PROPN
fnp-3025	1486	6	al	al	PROPN
fnp-3025	1486	7	.	.	PROPN
fnp-3025	1486	8	,	,	PUNCT
fnp-3025	1486	9	darwinian	darwinian	VERB
fnp-3025	1486	10	evolution	evolution	NOUN
fnp-3025	1486	11	of	of	ADP
fnp-3025	1486	12	prions	prion	NOUN
fnp-3025	1486	13	in	in	ADP
fnp-3025	1486	14	cell	cell	NOUN
fnp-3025	1486	15	culture	culture	NOUN
fnp-3025	1486	16	.	.	PUNCT
fnp-3025	1487	1	science	science	NOUN
fnp-3025	1487	2	,	,	PUNCT
fnp-3025	1487	3	2010	2010	NUM
fnp-3025	1487	4	.	.	PUNCT
fnp-3025	1488	1	327(5967	327(5967	NUM
fnp-3025	1488	2	):	):	PUNCT
fnp-3025	1488	3	p.	p.	NOUN
fnp-3025	1488	4	869	869	NUM
fnp-3025	1488	5	-	-	SYM
fnp-3025	1488	6	72	72	NUM
fnp-3025	1488	7	.	.	PUNCT
fnp-3025	1489	1	224	224	NUM
fnp-3025	1489	2	.	.	PUNCT
fnp-3025	1490	1	collinge	collinge	NOUN
fnp-3025	1490	2	,	,	PUNCT
fnp-3025	1490	3	j.	j.	PROPN
fnp-3025	1490	4	and	and	CCONJ
fnp-3025	1490	5	a.r	a.r	PROPN
fnp-3025	1490	6	.	.	PROPN
fnp-3025	1490	7	clarke	clarke	PROPN
fnp-3025	1490	8	,	,	PUNCT
fnp-3025	1490	9	a	a	DET
fnp-3025	1490	10	general	general	ADJ
fnp-3025	1490	11	model	model	NOUN
fnp-3025	1490	12	of	of	ADP
fnp-3025	1490	13	prion	prion	NOUN
fnp-3025	1490	14	strains	strain	NOUN
fnp-3025	1490	15	and	and	CCONJ
fnp-3025	1490	16	their	their	PRON
fnp-3025	1490	17	pathogenicity	pathogenicity	NOUN
fnp-3025	1490	18	.	.	PUNCT
fnp-3025	1491	1	science	science	NOUN
fnp-3025	1491	2	,	,	PUNCT
fnp-3025	1491	3	2007	2007	NUM
fnp-3025	1491	4	.	.	PUNCT
fnp-3025	1492	1	318(5852	318(5852	NUM
fnp-3025	1492	2	):	):	PUNCT
fnp-3025	1493	1	p.	p.	NOUN
fnp-3025	1493	2	930	930	NUM
fnp-3025	1493	3	-	-	SYM
fnp-3025	1493	4	6	6	NUM
fnp-3025	1493	5	.	.	NOUN
fnp-3025	1493	6	225	225	NUM
fnp-3025	1493	7	.	.	PUNCT
fnp-3025	1494	1	xu	xu	INTJ
fnp-3025	1494	2	,	,	PUNCT
fnp-3025	1494	3	g.	g.	PROPN
fnp-3025	1494	4	,	,	PUNCT
fnp-3025	1494	5	et	et	PROPN
fnp-3025	1494	6	al	al	PROPN
fnp-3025	1494	7	.	.	PROPN
fnp-3025	1494	8	,	,	PUNCT
fnp-3025	1494	9	diversity	diversity	NOUN
fnp-3025	1494	10	in	in	ADP
fnp-3025	1494	11	abeta	abeta	PROPN
fnp-3025	1494	12	deposit	deposit	NOUN
fnp-3025	1494	13	morphology	morphology	NOUN
fnp-3025	1494	14	and	and	CCONJ
fnp-3025	1494	15	secondary	secondary	ADJ
fnp-3025	1494	16	proteome	proteome	PROPN
fnp-3025	1494	17	insolubility	insolubility	NOUN
fnp-3025	1494	18	across	across	ADP
fnp-3025	1494	19	models	model	NOUN
fnp-3025	1494	20	of	of	ADP
fnp-3025	1494	21	alzheimer	alzheimer	NOUN
fnp-3025	1494	22	-	-	PUNCT
fnp-3025	1494	23	type	type	NOUN
fnp-3025	1494	24	amyloidosis	amyloidosis	NOUN
fnp-3025	1494	25	.	.	PUNCT
fnp-3025	1495	1	acta	acta	PROPN
fnp-3025	1495	2	neuropathol	neuropathol	PROPN
fnp-3025	1495	3	commun	commun	PROPN
fnp-3025	1495	4	,	,	PUNCT
fnp-3025	1495	5	2020	2020	NUM
fnp-3025	1495	6	.	.	PUNCT
fnp-3025	1496	1	8(1	8(1	NOUN
fnp-3025	1496	2	):	):	PUNCT
fnp-3025	1496	3	p.	p.	NOUN
fnp-3025	1496	4	43	43	NUM
fnp-3025	1496	5	.	.	PUNCT
fnp-3025	1497	1	226	226	NUM
fnp-3025	1497	2	.	.	X
fnp-3025	1498	1	cohen	cohen	PROPN
fnp-3025	1498	2	,	,	PUNCT
fnp-3025	1498	3	m.	m.	PROPN
fnp-3025	1498	4	,	,	PUNCT
fnp-3025	1498	5	b.	b.	PROPN
fnp-3025	1498	6	appleby	appleby	PROPN
fnp-3025	1498	7	,	,	PUNCT
fnp-3025	1498	8	and	and	CCONJ
fnp-3025	1498	9	j.g	j.g	PROPN
fnp-3025	1498	10	.	.	PROPN
fnp-3025	1498	11	safar	safar	PROPN
fnp-3025	1498	12	,	,	PUNCT
fnp-3025	1498	13	distinct	distinct	ADJ
fnp-3025	1498	14	prion	prion	NOUN
fnp-3025	1498	15	-	-	PUNCT
fnp-3025	1498	16	like	like	ADJ
fnp-3025	1498	17	strains	strain	NOUN
fnp-3025	1498	18	of	of	ADP
fnp-3025	1498	19	amyloid	amyloid	NOUN
fnp-3025	1498	20	beta	beta	NOUN
fnp-3025	1498	21	implicated	implicate	VERB
fnp-3025	1498	22	in	in	ADP
fnp-3025	1498	23	phenotypic	phenotypic	ADJ
fnp-3025	1498	24	diversity	diversity	NOUN
fnp-3025	1498	25	of	of	ADP
fnp-3025	1498	26	alzheimer	alzheimer	PROPN
fnp-3025	1498	27	’s	’s	PART
fnp-3025	1498	28	disease	disease	NOUN
fnp-3025	1498	29	.	.	PUNCT
fnp-3025	1499	1	prion	prion	NOUN
fnp-3025	1499	2	,	,	PUNCT
fnp-3025	1499	3	2016	2016	NUM
fnp-3025	1499	4	.	.	PUNCT
fnp-3025	1500	1	10(1	10(1	NUM
fnp-3025	1500	2	):	):	PUNCT
fnp-3025	1500	3	p.	p.	NOUN
fnp-3025	1500	4	9	9	NUM
fnp-3025	1500	5	-	-	SYM
fnp-3025	1500	6	17	17	NUM
fnp-3025	1500	7	.	.	PUNCT
fnp-3025	1501	1	227	227	NUM
fnp-3025	1501	2	.	.	PUNCT
fnp-3025	1501	3	condello	condello	PROPN
fnp-3025	1501	4	,	,	PUNCT
fnp-3025	1501	5	c.	c.	PROPN
fnp-3025	1501	6	,	,	PUNCT
fnp-3025	1501	7	et	et	PROPN
fnp-3025	1501	8	al	al	PROPN
fnp-3025	1501	9	.	.	PROPN
fnp-3025	1501	10	,	,	PUNCT
fnp-3025	1501	11	structural	structural	ADJ
fnp-3025	1501	12	heterogeneity	heterogeneity	NOUN
fnp-3025	1501	13	and	and	CCONJ
fnp-3025	1501	14	intersubject	intersubject	ADJ
fnp-3025	1501	15	variability	variability	NOUN
fnp-3025	1501	16	of	of	ADP
fnp-3025	1501	17	abeta	abeta	NOUN
fnp-3025	1501	18	in	in	ADP
fnp-3025	1501	19	familial	familial	ADJ
fnp-3025	1501	20	and	and	CCONJ
fnp-3025	1501	21	sporadic	sporadic	ADJ
fnp-3025	1501	22	alzheimer	alzheimer	PROPN
fnp-3025	1501	23	’s	’s	PART
fnp-3025	1501	24	disease	disease	NOUN
fnp-3025	1501	25	.	.	PUNCT
fnp-3025	1502	1	proc	proc	PROPN
fnp-3025	1502	2	natl	natl	PROPN
fnp-3025	1502	3	acad	acad	PROPN
fnp-3025	1502	4	sci	sci	PROPN
fnp-3025	1502	5	u	u	PROPN
fnp-3025	1502	6	s	s	PROPN
fnp-3025	1502	7	a	a	PRON
fnp-3025	1502	8	,	,	PUNCT
fnp-3025	1502	9	2018	2018	NUM
fnp-3025	1502	10	.	.	PUNCT
fnp-3025	1503	1	115(4	115(4	NUM
fnp-3025	1503	2	):	):	PUNCT
fnp-3025	1504	1	p.	p.	NOUN
fnp-3025	1504	2	e782	e782	PROPN
fnp-3025	1504	3	-	-	PUNCT
fnp-3025	1504	4	e791	e791	PROPN
fnp-3025	1504	5	.	.	PROPN
fnp-3025	1505	1	228	228	NUM
fnp-3025	1505	2	.	.	PUNCT
fnp-3025	1506	1	lu	lu	PROPN
fnp-3025	1506	2	,	,	PUNCT
fnp-3025	1506	3	j.x	j.x	PROPN
fnp-3025	1506	4	.	.	PROPN
fnp-3025	1506	5	,	,	PUNCT
fnp-3025	1506	6	et	et	PROPN
fnp-3025	1506	7	al	al	PROPN
fnp-3025	1506	8	.	.	PROPN
fnp-3025	1506	9	,	,	PUNCT
fnp-3025	1506	10	molecular	molecular	ADJ
fnp-3025	1506	11	structure	structure	NOUN
fnp-3025	1506	12	of	of	ADP
fnp-3025	1506	13	beta	beta	NOUN
fnp-3025	1506	14	-	-	PUNCT
fnp-3025	1506	15	amyloid	amyloid	NOUN
fnp-3025	1506	16	fibrils	fibril	NOUN
fnp-3025	1506	17	in	in	ADP
fnp-3025	1506	18	alzheimer	alzheimer	PROPN
fnp-3025	1506	19	’s	’s	PART
fnp-3025	1506	20	disease	disease	NOUN
fnp-3025	1506	21	brain	brain	NOUN
fnp-3025	1506	22	tissue	tissue	NOUN
fnp-3025	1506	23	.	.	PUNCT
fnp-3025	1507	1	cell	cell	NOUN
fnp-3025	1507	2	,	,	PUNCT
fnp-3025	1507	3	2013	2013	NUM
fnp-3025	1507	4	.	.	PUNCT
fnp-3025	1508	1	154(6	154(6	NUM
fnp-3025	1508	2	):	):	PUNCT
fnp-3025	1509	1	p.	p.	NOUN
fnp-3025	1509	2	1257	1257	NUM
fnp-3025	1509	3	-	-	SYM
fnp-3025	1509	4	68	68	NUM
fnp-3025	1509	5	.	.	PUNCT
fnp-3025	1509	6	229	229	NUM
fnp-3025	1509	7	.	.	PUNCT
fnp-3025	1510	1	qiang	qiang	PROPN
fnp-3025	1510	2	,	,	PUNCT
fnp-3025	1510	3	w.	w.	PROPN
fnp-3025	1510	4	,	,	PUNCT
fnp-3025	1510	5	et	et	PROPN
fnp-3025	1510	6	al	al	PROPN
fnp-3025	1510	7	.	.	PROPN
fnp-3025	1510	8	,	,	PUNCT
fnp-3025	1510	9	structural	structural	ADJ
fnp-3025	1510	10	variation	variation	NOUN
fnp-3025	1510	11	in	in	ADP
fnp-3025	1510	12	amyloid	amyloid	NOUN
fnp-3025	1510	13	-	-	PUNCT
fnp-3025	1510	14	beta	beta	NOUN
fnp-3025	1510	15	fibrils	fibril	NOUN
fnp-3025	1510	16	from	from	ADP
fnp-3025	1510	17	alzheimer	alzheimer	PROPN
fnp-3025	1510	18	’s	’s	PART
fnp-3025	1510	19	disease	disease	NOUN
fnp-3025	1510	20	clinical	clinical	ADJ
fnp-3025	1510	21	subtypes	subtype	NOUN
fnp-3025	1510	22	.	.	PUNCT
fnp-3025	1511	1	nature	nature	NOUN
fnp-3025	1511	2	,	,	PUNCT
fnp-3025	1511	3	2017	2017	NUM
fnp-3025	1511	4	.	.	PUNCT
fnp-3025	1512	1	541(7636	541(7636	NUM
fnp-3025	1512	2	):	):	PUNCT
fnp-3025	1512	3	p.	p.	NOUN
fnp-3025	1512	4	217	217	NUM
fnp-3025	1512	5	-	-	SYM
fnp-3025	1512	6	221	221	NUM
fnp-3025	1512	7	.	.	PUNCT
fnp-3025	1513	1	230	230	NUM
fnp-3025	1513	2	.	.	X
fnp-3025	1513	3	rasmussen	rasmussen	PROPN
fnp-3025	1513	4	,	,	PUNCT
fnp-3025	1513	5	j.	j.	PROPN
fnp-3025	1513	6	,	,	PUNCT
fnp-3025	1513	7	et	et	PROPN
fnp-3025	1513	8	al	al	PROPN
fnp-3025	1513	9	.	.	PROPN
fnp-3025	1513	10	,	,	PUNCT
fnp-3025	1513	11	amyloid	amyloid	NOUN
fnp-3025	1513	12	polymorphisms	polymorphism	NOUN
fnp-3025	1513	13	constitute	constitute	VERB
fnp-3025	1513	14	distinct	distinct	ADJ
fnp-3025	1513	15	clouds	cloud	NOUN
fnp-3025	1513	16	of	of	ADP
fnp-3025	1513	17	conformational	conformational	ADJ
fnp-3025	1513	18	variants	variant	NOUN
fnp-3025	1513	19	in	in	ADP
fnp-3025	1513	20	different	different	ADJ
fnp-3025	1513	21	etiological	etiological	ADJ
fnp-3025	1513	22	subtypes	subtype	NOUN
fnp-3025	1513	23	of	of	ADP
fnp-3025	1513	24	alzheimer	alzheimer	PROPN
fnp-3025	1513	25	’s	’s	PART
fnp-3025	1513	26	disease	disease	NOUN
fnp-3025	1513	27	.	.	PUNCT
fnp-3025	1514	1	proc	proc	PROPN
fnp-3025	1514	2	natl	natl	PROPN
fnp-3025	1514	3	acad	acad	PROPN
fnp-3025	1514	4	sci	sci	PROPN
fnp-3025	1514	5	u	u	PROPN
fnp-3025	1514	6	s	s	PROPN
fnp-3025	1514	7	a	a	PRON
fnp-3025	1514	8	,	,	PUNCT
fnp-3025	1514	9	2017	2017	NUM
fnp-3025	1514	10	.	.	PUNCT
fnp-3025	1515	1	114(49	114(49	NUM
fnp-3025	1515	2	):	):	PUNCT
fnp-3025	1515	3	p.	p.	NOUN
fnp-3025	1515	4	13018	13018	NUM
fnp-3025	1515	5	-	-	SYM
fnp-3025	1515	6	13023	13023	NUM
fnp-3025	1515	7	.	.	PUNCT
fnp-3025	1516	1	231	231	NUM
fnp-3025	1516	2	.	.	PUNCT
fnp-3025	1516	3	watts	watts	PROPN
fnp-3025	1516	4	,	,	PUNCT
fnp-3025	1516	5	j.c	j.c	PROPN
fnp-3025	1516	6	.	.	PROPN
fnp-3025	1516	7	,	,	PUNCT
fnp-3025	1516	8	et	et	PROPN
fnp-3025	1516	9	al	al	PROPN
fnp-3025	1516	10	.	.	PROPN
fnp-3025	1516	11	,	,	PUNCT
fnp-3025	1516	12	serial	serial	ADJ
fnp-3025	1516	13	propagation	propagation	NOUN
fnp-3025	1516	14	of	of	ADP
fnp-3025	1516	15	distinct	distinct	ADJ
fnp-3025	1516	16	strains	strain	NOUN
fnp-3025	1516	17	of	of	ADP
fnp-3025	1516	18	abeta	abeta	NOUN
fnp-3025	1516	19	prions	prion	NOUN
fnp-3025	1516	20	from	from	ADP
fnp-3025	1516	21	alzheimer	alzheimer	PROPN
fnp-3025	1516	22	’s	’s	PART
fnp-3025	1516	23	disease	disease	NOUN
fnp-3025	1516	24	patients	patient	NOUN
fnp-3025	1516	25	.	.	PUNCT
fnp-3025	1517	1	proc	proc	PROPN
fnp-3025	1517	2	natl	natl	PROPN
fnp-3025	1517	3	acad	acad	PROPN
fnp-3025	1517	4	sci	sci	PROPN
fnp-3025	1517	5	u	u	PROPN
fnp-3025	1517	6	s	s	PROPN
fnp-3025	1517	7	a	a	PRON
fnp-3025	1517	8	,	,	PUNCT
fnp-3025	1517	9	2014	2014	NUM
fnp-3025	1517	10	.	.	PUNCT
fnp-3025	1518	1	111(28	111(28	NUM
fnp-3025	1518	2	):	):	PUNCT
fnp-3025	1519	1	p.	p.	NOUN
fnp-3025	1519	2	10323	10323	NUM
fnp-3025	1519	3	-	-	SYM
fnp-3025	1519	4	8	8	NUM
fnp-3025	1519	5	.	.	X
fnp-3025	1519	6	232	232	NUM
fnp-3025	1519	7	.	.	PUNCT
fnp-3025	1520	1	fitzpatrick	fitzpatrick	PROPN
fnp-3025	1520	2	,	,	PUNCT
fnp-3025	1520	3	a.w	a.w	PROPN
fnp-3025	1520	4	.	.	PROPN
fnp-3025	1520	5	and	and	CCONJ
fnp-3025	1520	6	h.r	h.r	PROPN
fnp-3025	1520	7	.	.	PROPN
fnp-3025	1520	8	saibil	saibil	PROPN
fnp-3025	1520	9	,	,	PUNCT
fnp-3025	1520	10	cryo	cryo	NOUN
fnp-3025	1520	11	-	-	PUNCT
fnp-3025	1520	12	em	em	PRON
fnp-3025	1520	13	of	of	ADP
fnp-3025	1520	14	amyloid	amyloid	NOUN
fnp-3025	1520	15	fibrils	fibril	NOUN
fnp-3025	1520	16	and	and	CCONJ
fnp-3025	1520	17	cellular	cellular	ADJ
fnp-3025	1520	18	aggregates	aggregate	NOUN
fnp-3025	1520	19	.	.	PUNCT
fnp-3025	1521	1	curr	curr	PROPN
fnp-3025	1521	2	opin	opin	PROPN
fnp-3025	1521	3	struct	struct	NOUN
fnp-3025	1521	4	biol	biol	NOUN
fnp-3025	1521	5	,	,	PUNCT
fnp-3025	1521	6	2019	2019	NUM
fnp-3025	1521	7	.	.	PUNCT
fnp-3025	1522	1	58	58	NUM
fnp-3025	1522	2	:	:	PUNCT
fnp-3025	1523	1	p.	p.	NOUN
fnp-3025	1523	2	34	34	NUM
fnp-3025	1523	3	-	-	SYM
fnp-3025	1523	4	42	42	NUM
fnp-3025	1523	5	.	.	PUNCT
fnp-3025	1523	6	233	233	NUM
fnp-3025	1523	7	.	.	PUNCT
fnp-3025	1524	1	paravastu	paravastu	PROPN
fnp-3025	1524	2	,	,	PUNCT
fnp-3025	1524	3	a.k	a.k	PROPN
fnp-3025	1524	4	.	.	PROPN
fnp-3025	1524	5	,	,	PUNCT
fnp-3025	1524	6	et	et	PROPN
fnp-3025	1524	7	al	al	PROPN
fnp-3025	1524	8	.	.	PROPN
fnp-3025	1524	9	,	,	PUNCT
fnp-3025	1524	10	molecular	molecular	ADJ
fnp-3025	1524	11	structural	structural	ADJ
fnp-3025	1524	12	basis	basis	NOUN
fnp-3025	1524	13	for	for	ADP
fnp-3025	1524	14	polymorphism	polymorphism	NOUN
fnp-3025	1524	15	in	in	ADP
fnp-3025	1524	16	alzheimer	alzheimer	PROPN
fnp-3025	1524	17	’s	’s	PART
fnp-3025	1524	18	beta	beta	NOUN
fnp-3025	1524	19	-	-	PUNCT
fnp-3025	1524	20	amyloid	amyloid	NOUN
fnp-3025	1524	21	fibrils	fibril	NOUN
fnp-3025	1524	22	.	.	PUNCT
fnp-3025	1525	1	proc	proc	PROPN
fnp-3025	1525	2	natl	natl	PROPN
fnp-3025	1525	3	acad	acad	PROPN
fnp-3025	1525	4	sci	sci	PROPN
fnp-3025	1525	5	u	u	PROPN
fnp-3025	1525	6	s	s	PROPN
fnp-3025	1525	7	a	a	PRON
fnp-3025	1525	8	,	,	PUNCT
fnp-3025	1525	9	2008	2008	NUM
fnp-3025	1525	10	.	.	PUNCT
fnp-3025	1526	1	105(47	105(47	NUM
fnp-3025	1526	2	):	):	PUNCT
fnp-3025	1527	1	p.	p.	NOUN
fnp-3025	1527	2	18349	18349	NUM
fnp-3025	1527	3	-	-	SYM
fnp-3025	1527	4	54	54	NUM
fnp-3025	1527	5	.	.	PUNCT
fnp-3025	1527	6	234	234	NUM
fnp-3025	1527	7	.	.	PUNCT
fnp-3025	1528	1	sachse	sachse	PROPN
fnp-3025	1528	2	,	,	PUNCT
fnp-3025	1528	3	c.	c.	PROPN
fnp-3025	1528	4	,	,	PUNCT
fnp-3025	1528	5	m.	m.	NOUN
fnp-3025	1528	6	fandrich	fandrich	PROPN
fnp-3025	1528	7	,	,	PUNCT
fnp-3025	1528	8	and	and	CCONJ
fnp-3025	1528	9	n.	n.	PROPN
fnp-3025	1528	10	grigorieff	grigorieff	PROPN
fnp-3025	1528	11	,	,	PUNCT
fnp-3025	1528	12	paired	pair	VERB
fnp-3025	1528	13	beta	beta	NOUN
fnp-3025	1528	14	-	-	PUNCT
fnp-3025	1528	15	sheet	sheet	NOUN
fnp-3025	1528	16	structure	structure	NOUN
fnp-3025	1528	17	of	of	ADP
fnp-3025	1528	18	an	an	DET
fnp-3025	1528	19	abeta(1	abeta(1	NOUN
fnp-3025	1528	20	-	-	SYM
fnp-3025	1528	21	40	40	NUM
fnp-3025	1528	22	)	)	PUNCT
fnp-3025	1528	23	amyloid	amyloid	NOUN
fnp-3025	1528	24	fibril	fibril	PROPN
fnp-3025	1528	25	revealed	reveal	VERB
fnp-3025	1528	26	by	by	ADP
fnp-3025	1528	27	electron	electron	NOUN
fnp-3025	1528	28	microscopy	microscopy	NOUN
fnp-3025	1528	29	.	.	PUNCT
fnp-3025	1529	1	proc	proc	PROPN
fnp-3025	1529	2	natl	natl	PROPN
fnp-3025	1529	3	acad	acad	PROPN
fnp-3025	1529	4	sci	sci	PROPN
fnp-3025	1529	5	u	u	PROPN
fnp-3025	1529	6	s	s	PROPN
fnp-3025	1529	7	a	a	PRON
fnp-3025	1529	8	,	,	PUNCT
fnp-3025	1529	9	2008	2008	NUM
fnp-3025	1529	10	.	.	PUNCT
fnp-3025	1530	1	105(21	105(21	NUM
fnp-3025	1530	2	):	):	PUNCT
fnp-3025	1531	1	p.	p.	NOUN
fnp-3025	1531	2	7462	7462	NUM
fnp-3025	1531	3	-	-	SYM
fnp-3025	1531	4	6	6	NUM
fnp-3025	1531	5	.	.	NOUN
fnp-3025	1531	6	235	235	NUM
fnp-3025	1531	7	.	.	PUNCT
fnp-3025	1532	1	wang	wang	PROPN
fnp-3025	1532	2	,	,	PUNCT
fnp-3025	1532	3	h.	h.	PROPN
fnp-3025	1532	4	,	,	PUNCT
fnp-3025	1532	5	et	et	PROPN
fnp-3025	1532	6	al	al	PROPN
fnp-3025	1532	7	.	.	PROPN
fnp-3025	1532	8	,	,	PUNCT
fnp-3025	1532	9	polymorphic	polymorphic	ADJ
fnp-3025	1532	10	abeta42	abeta42	NOUN
fnp-3025	1532	11	fibrils	fibril	NOUN
fnp-3025	1532	12	adopt	adopt	VERB
fnp-3025	1532	13	similar	similar	ADJ
fnp-3025	1532	14	secondary	secondary	ADJ
fnp-3025	1532	15	structure	structure	NOUN
fnp-3025	1532	16	but	but	CCONJ
fnp-3025	1532	17	differ	differ	VERB
fnp-3025	1532	18	in	in	ADP
fnp-3025	1532	19	cross	cross	ADJ
fnp-3025	1532	20	-	-	ADJ
fnp-3025	1532	21	strand	strand	ADJ
fnp-3025	1532	22	side	side	NOUN
fnp-3025	1532	23	chain	chain	NOUN
fnp-3025	1532	24	stacking	stack	VERB
fnp-3025	1532	25	interactions	interaction	NOUN
fnp-3025	1532	26	within	within	ADP
fnp-3025	1532	27	the	the	DET
fnp-3025	1532	28	same	same	ADJ
fnp-3025	1532	29	beta	beta	NOUN
fnp-3025	1532	30	-	-	PUNCT
fnp-3025	1532	31	sheet	sheet	NOUN
fnp-3025	1532	32	.	.	PUNCT
fnp-3025	1533	1	sci	sci	PROPN
fnp-3025	1533	2	rep	rep	PROPN
fnp-3025	1533	3	,	,	PUNCT
fnp-3025	1533	4	2020	2020	NUM
fnp-3025	1533	5	.	.	PUNCT
fnp-3025	1534	1	10(1	10(1	NUM
fnp-3025	1534	2	):	):	PUNCT
fnp-3025	1534	3	p.	p.	NOUN
fnp-3025	1534	4	5720	5720	NUM
fnp-3025	1534	5	.	.	PUNCT
fnp-3025	1535	1	236	236	NUM
fnp-3025	1535	2	.	.	PUNCT
fnp-3025	1536	1	revesz	revesz	ADJ
fnp-3025	1536	2	,	,	PUNCT
fnp-3025	1536	3	t.	t.	PROPN
fnp-3025	1536	4	,	,	PUNCT
fnp-3025	1536	5	et	et	PROPN
fnp-3025	1536	6	al	al	PROPN
fnp-3025	1536	7	.	.	PROPN
fnp-3025	1536	8	,	,	PUNCT
fnp-3025	1536	9	cerebral	cerebral	ADJ
fnp-3025	1536	10	amyloid	amyloid	NOUN
fnp-3025	1536	11	angiopathies	angiopathy	NOUN
fnp-3025	1536	12	:	:	PUNCT
fnp-3025	1536	13	a	a	DET
fnp-3025	1536	14	pathologic	pathologic	ADJ
fnp-3025	1536	15	,	,	PUNCT
fnp-3025	1536	16	biochemical	biochemical	ADJ
fnp-3025	1536	17	,	,	PUNCT
fnp-3025	1536	18	and	and	CCONJ
fnp-3025	1536	19	genetic	genetic	ADJ
fnp-3025	1536	20	view	view	NOUN
fnp-3025	1536	21	.	.	PUNCT
fnp-3025	1537	1	j	j	PROPN
fnp-3025	1537	2	neuropathol	neuropathol	PROPN
fnp-3025	1537	3	exp	exp	PROPN
fnp-3025	1537	4	neurol	neurol	PROPN
fnp-3025	1537	5	,	,	PUNCT
fnp-3025	1537	6	2003	2003	NUM
fnp-3025	1537	7	.	.	PUNCT
fnp-3025	1538	1	62(9	62(9	NUM
fnp-3025	1538	2	):	):	PUNCT
fnp-3025	1539	1	p.	p.	NOUN
fnp-3025	1539	2	885	885	NUM
fnp-3025	1539	3	-	-	SYM
fnp-3025	1539	4	98	98	NUM
fnp-3025	1539	5	.	.	PUNCT
fnp-3025	1539	6	237	237	NUM
fnp-3025	1539	7	.	.	PUNCT
fnp-3025	1540	1	biffi	biffi	ADV
fnp-3025	1540	2	,	,	PUNCT
fnp-3025	1540	3	a.	a.	NOUN
fnp-3025	1540	4	and	and	CCONJ
fnp-3025	1540	5	s.m	s.m	PROPN
fnp-3025	1540	6	.	.	PROPN
fnp-3025	1540	7	greenberg	greenberg	PROPN
fnp-3025	1540	8	,	,	PUNCT
fnp-3025	1540	9	cerebral	cerebral	ADJ
fnp-3025	1540	10	amyloid	amyloid	NOUN
fnp-3025	1540	11	angiopathy	angiopathy	NOUN
fnp-3025	1540	12	:	:	PUNCT
fnp-3025	1540	13	a	a	DET
fnp-3025	1540	14	systematic	systematic	ADJ
fnp-3025	1540	15	review	review	NOUN
fnp-3025	1540	16	.	.	PUNCT
fnp-3025	1541	1	j	j	PROPN
fnp-3025	1541	2	clin	clin	PROPN
fnp-3025	1541	3	neurol	neurol	PROPN
fnp-3025	1541	4	,	,	PUNCT
fnp-3025	1541	5	2011	2011	NUM
fnp-3025	1541	6	.	.	PUNCT
fnp-3025	1542	1	7(1	7(1	NUM
fnp-3025	1542	2	):	):	PUNCT
fnp-3025	1542	3	p.	p.	NOUN
fnp-3025	1542	4	1	1	NUM
fnp-3025	1542	5	-	-	SYM
fnp-3025	1542	6	9	9	NUM
fnp-3025	1542	7	.	.	NOUN
fnp-3025	1542	8	238	238	NUM
fnp-3025	1542	9	.	.	PUNCT
fnp-3025	1543	1	haan	haan	PROPN
fnp-3025	1543	2	,	,	PUNCT
fnp-3025	1543	3	j.	j.	PROPN
fnp-3025	1543	4	,	,	PUNCT
fnp-3025	1543	5	et	et	PROPN
fnp-3025	1543	6	al	al	PROPN
fnp-3025	1543	7	.	.	PROPN
fnp-3025	1543	8	,	,	PUNCT
fnp-3025	1543	9	dementia	dementia	NOUN
fnp-3025	1543	10	in	in	ADP
fnp-3025	1543	11	hereditary	hereditary	ADJ
fnp-3025	1543	12	cerebral	cerebral	ADJ
fnp-3025	1543	13	hemorrhage	hemorrhage	NOUN
fnp-3025	1543	14	with	with	ADP
fnp-3025	1543	15	amyloidosis	amyloidosis	NOUN
fnp-3025	1543	16	-	-	PUNCT
fnp-3025	1543	17	dutch	dutch	NOUN
fnp-3025	1543	18	type	type	NOUN
fnp-3025	1543	19	.	.	PUNCT
fnp-3025	1544	1	arch	arch	ADJ
fnp-3025	1544	2	neurol	neurol	NOUN
fnp-3025	1544	3	,	,	PUNCT
fnp-3025	1544	4	1990	1990	NUM
fnp-3025	1544	5	.	.	PUNCT
fnp-3025	1545	1	47(9	47(9	NOUN
fnp-3025	1545	2	):	):	PUNCT
fnp-3025	1546	1	p.	p.	NOUN
fnp-3025	1546	2	965	965	NUM
fnp-3025	1546	3	-	-	SYM
fnp-3025	1546	4	7	7	NUM
fnp-3025	1546	5	.	.	NOUN
fnp-3025	1546	6	239	239	NUM
fnp-3025	1546	7	.	.	PUNCT
fnp-3025	1547	1	maat	maat	NOUN
fnp-3025	1547	2	-	-	PUNCT
fnp-3025	1547	3	schieman	schieman	NOUN
fnp-3025	1547	4	,	,	PUNCT
fnp-3025	1547	5	m.l	m.l	PROPN
fnp-3025	1547	6	.	.	PROPN
fnp-3025	1547	7	,	,	PUNCT
fnp-3025	1547	8	et	et	PROPN
fnp-3025	1547	9	al	al	PROPN
fnp-3025	1547	10	.	.	PROPN
fnp-3025	1547	11	,	,	PUNCT
fnp-3025	1547	12	hereditary	hereditary	ADJ
fnp-3025	1547	13	cerebral	cerebral	ADJ
fnp-3025	1547	14	hemorrhage	hemorrhage	NOUN
fnp-3025	1547	15	with	with	ADP
fnp-3025	1547	16	amyloidosis	amyloidosis	NOUN
fnp-3025	1547	17	-	-	PUNCT
fnp-3025	1547	18	dutch	dutch	NOUN
fnp-3025	1547	19	type	type	NOUN
fnp-3025	1547	20	(	(	PUNCT
fnp-3025	1547	21	hchwa	hchwa	PROPN
fnp-3025	1547	22	-	-	PUNCT
fnp-3025	1547	23	d	d	PROPN
fnp-3025	1547	24	):	):	PUNCT
fnp-3025	1547	25	ii	ii	PROPN
fnp-3025	1547	26	--	--	PUNCT
fnp-3025	1547	27	a	a	DET
fnp-3025	1547	28	review	review	NOUN
fnp-3025	1547	29	of	of	ADP
fnp-3025	1547	30	histopathological	histopathological	ADJ
fnp-3025	1547	31	aspects	aspect	NOUN
fnp-3025	1547	32	.	.	PUNCT
fnp-3025	1548	1	brain	brain	NOUN
fnp-3025	1548	2	pathol	pathol	NOUN
fnp-3025	1548	3	,	,	PUNCT
fnp-3025	1548	4	1996	1996	NUM
fnp-3025	1548	5	.	.	PUNCT
fnp-3025	1549	1	6(2	6(2	NUM
fnp-3025	1549	2	):	):	PUNCT
fnp-3025	1550	1	p.	p.	NOUN
fnp-3025	1550	2	115	115	NUM
fnp-3025	1550	3	-	-	SYM
fnp-3025	1550	4	20	20	NUM
fnp-3025	1550	5	.	.	PUNCT
fnp-3025	1550	6	240	240	NUM
fnp-3025	1550	7	.	.	PUNCT
fnp-3025	1551	1	revesz	revesz	ADJ
fnp-3025	1551	2	,	,	PUNCT
fnp-3025	1551	3	t.	t.	PROPN
fnp-3025	1551	4	,	,	PUNCT
fnp-3025	1551	5	et	et	PROPN
fnp-3025	1551	6	al	al	PROPN
fnp-3025	1551	7	.	.	PROPN
fnp-3025	1551	8	,	,	PUNCT
fnp-3025	1551	9	genetics	genetic	NOUN
fnp-3025	1551	10	and	and	CCONJ
fnp-3025	1551	11	molecular	molecular	ADJ
fnp-3025	1551	12	pathogenesis	pathogenesis	NOUN
fnp-3025	1551	13	of	of	ADP
fnp-3025	1551	14	sporadic	sporadic	ADJ
fnp-3025	1551	15	and	and	CCONJ
fnp-3025	1551	16	hereditary	hereditary	ADJ
fnp-3025	1551	17	cerebral	cerebral	ADJ
fnp-3025	1551	18	amyloid	amyloid	NOUN
fnp-3025	1551	19	angiopathies	angiopathy	NOUN
fnp-3025	1551	20	.	.	PUNCT
fnp-3025	1552	1	acta	acta	PROPN
fnp-3025	1552	2	neuropathol	neuropathol	PROPN
fnp-3025	1552	3	,	,	PUNCT
fnp-3025	1552	4	2009	2009	NUM
fnp-3025	1552	5	.	.	PUNCT
fnp-3025	1553	1	118(1	118(1	NUM
fnp-3025	1553	2	):	):	PUNCT
fnp-3025	1553	3	p.	p.	NOUN
fnp-3025	1553	4	115	115	NUM
fnp-3025	1553	5	-	-	SYM
fnp-3025	1553	6	30	30	NUM
fnp-3025	1553	7	.	.	PUNCT
fnp-3025	1554	1	241	241	X
fnp-3025	1554	2	.	.	PUNCT
fnp-3025	1554	3	attems	attems	PROPN
fnp-3025	1554	4	,	,	PUNCT
fnp-3025	1554	5	j.	j.	PROPN
fnp-3025	1554	6	,	,	PUNCT
fnp-3025	1554	7	sporadic	sporadic	ADJ
fnp-3025	1554	8	cerebral	cerebral	ADJ
fnp-3025	1554	9	amyloid	amyloid	NOUN
fnp-3025	1554	10	angiopathy	angiopathy	NOUN
fnp-3025	1554	11	:	:	PUNCT
fnp-3025	1554	12	pathology	pathology	NOUN
fnp-3025	1554	13	,	,	PUNCT
fnp-3025	1554	14	clinical	clinical	ADJ
fnp-3025	1554	15	implications	implication	NOUN
fnp-3025	1554	16	,	,	PUNCT
fnp-3025	1554	17	and	and	CCONJ
fnp-3025	1554	18	possible	possible	ADJ
fnp-3025	1554	19	pathomechanisms	pathomechanism	NOUN
fnp-3025	1554	20	.	.	PUNCT
fnp-3025	1555	1	acta	acta	PROPN
fnp-3025	1555	2	neuropathol	neuropathol	PROPN
fnp-3025	1555	3	,	,	PUNCT
fnp-3025	1555	4	2005	2005	NUM
fnp-3025	1555	5	.	.	PUNCT
fnp-3025	1556	1	110(4	110(4	NUM
fnp-3025	1556	2	):	):	PUNCT
fnp-3025	1556	3	p.	p.	NOUN
fnp-3025	1556	4	345	345	NUM
fnp-3025	1556	5	-	-	SYM
fnp-3025	1556	6	59	59	NUM
fnp-3025	1556	7	.	.	PUNCT
fnp-3025	1556	8	242	242	NUM
fnp-3025	1556	9	.	.	PUNCT
fnp-3025	1557	1	attems	attem	NOUN
fnp-3025	1557	2	,	,	PUNCT
fnp-3025	1557	3	j.	j.	PROPN
fnp-3025	1557	4	and	and	CCONJ
fnp-3025	1557	5	k.a	k.a	PROPN
fnp-3025	1557	6	.	.	PUNCT
fnp-3025	1558	1	jellinger	jellinger	PROPN
fnp-3025	1558	2	,	,	PUNCT
fnp-3025	1558	3	the	the	DET
fnp-3025	1558	4	overlap	overlap	NOUN
fnp-3025	1558	5	between	between	ADP
fnp-3025	1558	6	vascular	vascular	ADJ
fnp-3025	1558	7	disease	disease	NOUN
fnp-3025	1558	8	and	and	CCONJ
fnp-3025	1558	9	alzheimer	alzheimer	PROPN
fnp-3025	1558	10	’s	’s	PART
fnp-3025	1558	11	disease	disease	NOUN
fnp-3025	1558	12	--	--	PUNCT
fnp-3025	1558	13	lessons	lesson	NOUN
fnp-3025	1558	14	from	from	ADP
fnp-3025	1558	15	pathology	pathology	NOUN
fnp-3025	1558	16	.	.	PUNCT
fnp-3025	1559	1	bmc	bmc	PROPN
fnp-3025	1559	2	med	med	PROPN
fnp-3025	1559	3	,	,	PUNCT
fnp-3025	1559	4	2014	2014	NUM
fnp-3025	1559	5	.	.	PUNCT
fnp-3025	1560	1	12	12	NUM
fnp-3025	1560	2	:	:	PUNCT
fnp-3025	1560	3	p.	p.	NOUN
fnp-3025	1560	4	206	206	NUM
fnp-3025	1560	5	.	.	PUNCT
fnp-3025	1561	1	243	243	NUM
fnp-3025	1561	2	.	.	PUNCT
fnp-3025	1562	1	kapasi	kapasi	PROPN
fnp-3025	1562	2	,	,	PUNCT
fnp-3025	1562	3	a.	a.	NOUN
fnp-3025	1562	4	and	and	CCONJ
fnp-3025	1562	5	j.a	j.a	PROPN
fnp-3025	1562	6	.	.	PROPN
fnp-3025	1562	7	schneider	schneider	PROPN
fnp-3025	1562	8	,	,	PUNCT
fnp-3025	1562	9	vascular	vascular	ADJ
fnp-3025	1562	10	contributions	contribution	NOUN
fnp-3025	1562	11	to	to	ADP
fnp-3025	1562	12	cognitive	cognitive	ADJ
fnp-3025	1562	13	impairment	impairment	NOUN
fnp-3025	1562	14	,	,	PUNCT
fnp-3025	1562	15	clinical	clinical	ADJ
fnp-3025	1562	16	alzheimer	alzheimer	PROPN
fnp-3025	1562	17	’s	’s	PART
fnp-3025	1562	18	disease	disease	NOUN
fnp-3025	1562	19	,	,	PUNCT
fnp-3025	1562	20	and	and	CCONJ
fnp-3025	1562	21	dementia	dementia	NOUN
fnp-3025	1562	22	in	in	ADP
fnp-3025	1562	23	older	old	ADJ
fnp-3025	1562	24	persons	person	NOUN
fnp-3025	1562	25	.	.	PUNCT
fnp-3025	1563	1	biochim	biochim	PROPN
fnp-3025	1563	2	biophys	biophy	NOUN
fnp-3025	1563	3	acta	acta	PROPN
fnp-3025	1563	4	,	,	PUNCT
fnp-3025	1563	5	2016	2016	NUM
fnp-3025	1563	6	.	.	PUNCT
fnp-3025	1564	1	1862(5	1862(5	NUM
fnp-3025	1564	2	):	):	PUNCT
fnp-3025	1564	3	p.	p.	NOUN
fnp-3025	1564	4	878	878	NUM
fnp-3025	1564	5	-	-	SYM
fnp-3025	1564	6	86	86	NUM
fnp-3025	1564	7	.	.	PUNCT
fnp-3025	1565	1	244	244	NUM
fnp-3025	1565	2	.	.	PUNCT
fnp-3025	1566	1	vinters	vinter	NOUN
fnp-3025	1566	2	,	,	PUNCT
fnp-3025	1566	3	h.v	h.v	PROPN
fnp-3025	1566	4	.	.	PROPN
fnp-3025	1566	5	,	,	PUNCT
fnp-3025	1566	6	emerging	emerge	VERB
fnp-3025	1566	7	concepts	concept	NOUN
fnp-3025	1566	8	in	in	ADP
fnp-3025	1566	9	alzheimer	alzheimer	PROPN
fnp-3025	1566	10	’s	’s	PART
fnp-3025	1566	11	disease	disease	NOUN
fnp-3025	1566	12	.	.	PUNCT
fnp-3025	1567	1	annu	annu	PROPN
fnp-3025	1567	2	rev	rev	PROPN
fnp-3025	1567	3	pathol	pathol	PROPN
fnp-3025	1567	4	,	,	PUNCT
fnp-3025	1567	5	2015	2015	NUM
fnp-3025	1567	6	.	.	PUNCT
fnp-3025	1568	1	10	10	NUM
fnp-3025	1568	2	:	:	PUNCT
fnp-3025	1568	3	p.	p.	NOUN
fnp-3025	1568	4	291	291	NUM
fnp-3025	1568	5	-	-	SYM
fnp-3025	1568	6	319	319	NUM
fnp-3025	1568	7	.	.	PUNCT
fnp-3025	1569	1	245	245	NUM
fnp-3025	1569	2	.	.	PUNCT
fnp-3025	1570	1	auriel	auriel	PROPN
fnp-3025	1570	2	,	,	PUNCT
fnp-3025	1570	3	e.	e.	PROPN
fnp-3025	1570	4	and	and	CCONJ
fnp-3025	1570	5	s.m	s.m	PROPN
fnp-3025	1570	6	.	.	PROPN
fnp-3025	1570	7	greenberg	greenberg	PROPN
fnp-3025	1570	8	,	,	PUNCT
fnp-3025	1570	9	the	the	DET
fnp-3025	1570	10	pathophysiology	pathophysiology	NOUN
fnp-3025	1570	11	and	and	CCONJ
fnp-3025	1570	12	clinical	clinical	ADJ
fnp-3025	1570	13	presentation	presentation	NOUN
fnp-3025	1570	14	of	of	ADP
fnp-3025	1570	15	cerebral	cerebral	ADJ
fnp-3025	1570	16	amyloid	amyloid	NOUN
fnp-3025	1570	17	angiopathy	angiopathy	NOUN
fnp-3025	1570	18	.	.	PUNCT
fnp-3025	1571	1	curr	curr	PROPN
fnp-3025	1571	2	atheroscler	atheroscler	PROPN
fnp-3025	1571	3	rep	rep	PROPN
fnp-3025	1571	4	,	,	PUNCT
fnp-3025	1571	5	2012	2012	NUM
fnp-3025	1571	6	.	.	PUNCT
fnp-3025	1572	1	14(4	14(4	NUM
fnp-3025	1572	2	):	):	PUNCT
fnp-3025	1572	3	p.	p.	NOUN
fnp-3025	1572	4	343	343	NUM
fnp-3025	1572	5	-	-	SYM
fnp-3025	1572	6	50	50	NUM
fnp-3025	1572	7	.	.	PUNCT
fnp-3025	1573	1	246	246	NUM
fnp-3025	1573	2	.	.	X
fnp-3025	1574	1	olichney	olichney	PROPN
fnp-3025	1574	2	,	,	PUNCT
fnp-3025	1574	3	j.m	j.m	PROPN
fnp-3025	1574	4	.	.	PROPN
fnp-3025	1574	5	,	,	PUNCT
fnp-3025	1574	6	et	et	PROPN
fnp-3025	1574	7	al	al	PROPN
fnp-3025	1574	8	.	.	PROPN
fnp-3025	1574	9	,	,	PUNCT
fnp-3025	1574	10	cerebral	cerebral	ADJ
fnp-3025	1574	11	infarction	infarction	NOUN
fnp-3025	1574	12	in	in	ADP
fnp-3025	1574	13	alzheimer	alzheimer	PROPN
fnp-3025	1574	14	’s	’s	PART
fnp-3025	1574	15	disease	disease	NOUN
fnp-3025	1574	16	is	be	AUX
fnp-3025	1574	17	associated	associate	VERB
fnp-3025	1574	18	with	with	ADP
fnp-3025	1574	19	severe	severe	ADJ
fnp-3025	1574	20	amyloid	amyloid	NOUN
fnp-3025	1574	21	angiopathy	angiopathy	NOUN
fnp-3025	1574	22	and	and	CCONJ
fnp-3025	1574	23	hypertension	hypertension	NOUN
fnp-3025	1574	24	.	.	PUNCT
fnp-3025	1575	1	arch	arch	ADJ
fnp-3025	1575	2	neurol	neurol	NOUN
fnp-3025	1575	3	,	,	PUNCT
fnp-3025	1575	4	1995	1995	NUM
fnp-3025	1575	5	.	.	PUNCT
fnp-3025	1576	1	52(7	52(7	NUM
fnp-3025	1576	2	):	):	PUNCT
fnp-3025	1576	3	p.	p.	NOUN
fnp-3025	1576	4	702	702	NUM
fnp-3025	1576	5	-	-	SYM
fnp-3025	1576	6	8	8	NUM
fnp-3025	1576	7	.	.	NUM
fnp-3025	1576	8	247	247	NUM
fnp-3025	1576	9	.	.	PUNCT
fnp-3025	1577	1	kamara	kamara	PROPN
fnp-3025	1577	2	,	,	PUNCT
fnp-3025	1577	3	d.m	d.m	PROPN
fnp-3025	1577	4	.	.	PROPN
fnp-3025	1577	5	,	,	PUNCT
fnp-3025	1577	6	et	et	PROPN
fnp-3025	1577	7	al	al	PROPN
fnp-3025	1577	8	.	.	PROPN
fnp-3025	1577	9	,	,	PUNCT
fnp-3025	1577	10	cerebral	cerebral	ADJ
fnp-3025	1577	11	amyloid	amyloid	NOUN
fnp-3025	1577	12	angiopathy	angiopathy	NOUN
fnp-3025	1577	13	:	:	PUNCT
fnp-3025	1577	14	similarity	similarity	NOUN
fnp-3025	1577	15	in	in	ADP
fnp-3025	1577	16	african	african	PROPN
fnp-3025	1577	17	-	-	PUNCT
fnp-3025	1577	18	americans	americans	PROPN
fnp-3025	1577	19	and	and	CCONJ
fnp-3025	1577	20	caucasians	caucasian	NOUN
fnp-3025	1577	21	with	with	ADP
fnp-3025	1577	22	alzheimer	alzheimer	PROPN
fnp-3025	1577	23	’s	’s	PART
fnp-3025	1577	24	disease	disease	NOUN
fnp-3025	1577	25	.	.	PUNCT
fnp-3025	1578	1	j	j	PROPN
fnp-3025	1578	2	alzheimers	alzheimers	PROPN
fnp-3025	1578	3	dis	dis	PROPN
fnp-3025	1578	4	,	,	PUNCT
fnp-3025	1578	5	2018	2018	NUM
fnp-3025	1578	6	.	.	PUNCT
fnp-3025	1579	1	62(4	62(4	NUM
fnp-3025	1579	2	):	):	PUNCT
fnp-3025	1579	3	p.	p.	NOUN
fnp-3025	1579	4	1815	1815	NUM
fnp-3025	1579	5	-	-	SYM
fnp-3025	1579	6	1826	1826	NUM
fnp-3025	1579	7	.	.	PUNCT
fnp-3025	1580	1	248	248	NUM
fnp-3025	1580	2	.	.	PUNCT
fnp-3025	1581	1	bornebroek	bornebroek	NOUN
fnp-3025	1581	2	,	,	PUNCT
fnp-3025	1581	3	m.	m.	NOUN
fnp-3025	1581	4	,	,	PUNCT
fnp-3025	1581	5	et	et	PROPN
fnp-3025	1581	6	al	al	PROPN
fnp-3025	1581	7	.	.	PROPN
fnp-3025	1581	8	,	,	PUNCT
fnp-3025	1581	9	hereditary	hereditary	ADJ
fnp-3025	1581	10	cerebral	cerebral	ADJ
fnp-3025	1581	11	hemorrhage	hemorrhage	NOUN
fnp-3025	1581	12	with	with	ADP
fnp-3025	1581	13	amyloidosis	amyloidosis	NOUN
fnp-3025	1581	14	-	-	PUNCT
fnp-3025	1581	15	dutch	dutch	NOUN
fnp-3025	1581	16	type	type	NOUN
fnp-3025	1581	17	(	(	PUNCT
fnp-3025	1581	18	hchwa	hchwa	PROPN
fnp-3025	1581	19	-	-	PUNCT
fnp-3025	1581	20	d	d	NOUN
fnp-3025	1581	21	):	):	PUNCT
fnp-3025	1581	22	i	i	PRON
fnp-3025	1581	23	--	--	PUNCT
fnp-3025	1581	24	a	a	DET
fnp-3025	1581	25	review	review	NOUN
fnp-3025	1581	26	of	of	ADP
fnp-3025	1581	27	clinical	clinical	ADJ
fnp-3025	1581	28	,	,	PUNCT
fnp-3025	1581	29	radiologic	radiologic	ADJ
fnp-3025	1581	30	and	and	CCONJ
fnp-3025	1581	31	genetic	genetic	ADJ
fnp-3025	1581	32	aspects	aspect	NOUN
fnp-3025	1581	33	.	.	PUNCT
fnp-3025	1582	1	brain	brain	NOUN
fnp-3025	1582	2	pathol	pathol	NOUN
fnp-3025	1582	3	,	,	PUNCT
fnp-3025	1582	4	1996	1996	NUM
fnp-3025	1582	5	.	.	PUNCT
fnp-3025	1583	1	6(2	6(2	NUM
fnp-3025	1583	2	):	):	PUNCT
fnp-3025	1584	1	p.	p.	NOUN
fnp-3025	1584	2	111	111	NUM
fnp-3025	1584	3	-	-	SYM
fnp-3025	1584	4	4	4	NUM
fnp-3025	1584	5	.	.	NOUN
fnp-3025	1584	6	249	249	NUM
fnp-3025	1584	7	.	.	PUNCT
fnp-3025	1585	1	kamp	kamp	PROPN
fnp-3025	1585	2	,	,	PUNCT
fnp-3025	1585	3	j.a	j.a	PROPN
fnp-3025	1585	4	.	.	PROPN
fnp-3025	1585	5	,	,	PUNCT
fnp-3025	1585	6	et	et	PROPN
fnp-3025	1585	7	al	al	PROPN
fnp-3025	1585	8	.	.	PROPN
fnp-3025	1585	9	,	,	PUNCT
fnp-3025	1585	10	amyloid	amyloid	NOUN
fnp-3025	1585	11	beta	beta	NOUN
fnp-3025	1585	12	in	in	ADP
fnp-3025	1585	13	hereditary	hereditary	ADJ
fnp-3025	1585	14	cerebral	cerebral	ADJ
fnp-3025	1585	15	hemorrhage	hemorrhage	NOUN
fnp-3025	1585	16	with	with	ADP
fnp-3025	1585	17	amyloidosis	amyloidosis	NOUN
fnp-3025	1585	18	-	-	PUNCT
fnp-3025	1585	19	dutch	dutch	NOUN
fnp-3025	1585	20	type	type	NOUN
fnp-3025	1585	21	.	.	PUNCT
fnp-3025	1586	1	rev	rev	PROPN
fnp-3025	1586	2	neurosci	neurosci	PROPN
fnp-3025	1586	3	,	,	PUNCT
fnp-3025	1586	4	2014	2014	NUM
fnp-3025	1586	5	.	.	PUNCT
fnp-3025	1587	1	25(5	25(5	NUM
fnp-3025	1587	2	):	):	PUNCT
fnp-3025	1588	1	p.	p.	NOUN
fnp-3025	1588	2	641	641	NUM
fnp-3025	1588	3	-	-	SYM
fnp-3025	1588	4	51	51	NUM
fnp-3025	1588	5	.	.	PUNCT
fnp-3025	1588	6	250	250	NUM
fnp-3025	1588	7	.	.	PUNCT
fnp-3025	1589	1	timmers	timmer	NOUN
fnp-3025	1589	2	,	,	PUNCT
fnp-3025	1589	3	w.f	w.f	PROPN
fnp-3025	1589	4	.	.	PROPN
fnp-3025	1589	5	,	,	PUNCT
fnp-3025	1589	6	et	et	PROPN
fnp-3025	1589	7	al	al	PROPN
fnp-3025	1589	8	.	.	PROPN
fnp-3025	1589	9	,	,	PUNCT
fnp-3025	1589	10	parenchymal	parenchymal	ADJ
fnp-3025	1589	11	preamyloid	preamyloid	NOUN
fnp-3025	1589	12	and	and	CCONJ
fnp-3025	1589	13	amyloid	amyloid	NOUN
fnp-3025	1589	14	deposits	deposit	NOUN
fnp-3025	1589	15	in	in	ADP
fnp-3025	1589	16	the	the	DET
fnp-3025	1589	17	brains	brain	NOUN
fnp-3025	1589	18	of	of	ADP
fnp-3025	1589	19	patients	patient	NOUN
fnp-3025	1589	20	with	with	ADP
fnp-3025	1589	21	hereditary	hereditary	ADJ
fnp-3025	1589	22	cerebral	cerebral	ADJ
fnp-3025	1589	23	hemorrhage	hemorrhage	NOUN
fnp-3025	1589	24	with	with	ADP
fnp-3025	1589	25	amyloidosis	amyloidosis	NOUN
fnp-3025	1589	26	--	--	PUNCT
fnp-3025	1589	27	dutch	dutch	ADJ
fnp-3025	1589	28	type	type	NOUN
fnp-3025	1589	29	.	.	PUNCT
fnp-3025	1590	1	neurosci	neurosci	PROPN
fnp-3025	1590	2	lett	lett	PROPN
fnp-3025	1590	3	,	,	PUNCT
fnp-3025	1590	4	1990	1990	NUM
fnp-3025	1590	5	.	.	PUNCT
fnp-3025	1591	1	118(2	118(2	NUM
fnp-3025	1591	2	):	):	PUNCT
fnp-3025	1591	3	p.	p.	NOUN
fnp-3025	1591	4	223	223	NUM
fnp-3025	1591	5	-	-	SYM
fnp-3025	1591	6	6	6	NUM
fnp-3025	1591	7	.	.	NOUN
fnp-3025	1591	8	251	251	NUM
fnp-3025	1591	9	.	.	PUNCT
fnp-3025	1592	1	van	van	PROPN
fnp-3025	1592	2	duinen	duinen	PROPN
fnp-3025	1592	3	,	,	PUNCT
fnp-3025	1592	4	s.g	s.g	PROPN
fnp-3025	1592	5	.	.	PROPN
fnp-3025	1592	6	,	,	PUNCT
fnp-3025	1592	7	et	et	PROPN
fnp-3025	1592	8	al	al	PROPN
fnp-3025	1592	9	.	.	PROPN
fnp-3025	1592	10	,	,	PUNCT
fnp-3025	1592	11	hereditary	hereditary	ADJ
fnp-3025	1592	12	cerebral	cerebral	ADJ
fnp-3025	1592	13	hemorrhage	hemorrhage	NOUN
fnp-3025	1592	14	with	with	ADP
fnp-3025	1592	15	amyloidosis	amyloidosis	NOUN
fnp-3025	1592	16	in	in	ADP
fnp-3025	1592	17	patients	patient	NOUN
fnp-3025	1592	18	of	of	ADP
fnp-3025	1592	19	dutch	dutch	ADJ
fnp-3025	1592	20	origin	origin	NOUN
fnp-3025	1592	21	is	be	AUX
fnp-3025	1592	22	related	relate	VERB
fnp-3025	1592	23	to	to	ADP
fnp-3025	1592	24	alzheimer	alzheimer	PROPN
fnp-3025	1592	25	disease	disease	NOUN
fnp-3025	1592	26	.	.	PUNCT
fnp-3025	1593	1	proc	proc	PROPN
fnp-3025	1593	2	natl	natl	PROPN
fnp-3025	1593	3	acad	acad	PROPN
fnp-3025	1593	4	sci	sci	PROPN
fnp-3025	1593	5	u	u	PROPN
fnp-3025	1593	6	s	s	PROPN
fnp-3025	1593	7	a	a	PRON
fnp-3025	1593	8	,	,	PUNCT
fnp-3025	1593	9	1987	1987	NUM
fnp-3025	1593	10	.	.	PUNCT
fnp-3025	1594	1	84(16	84(16	NUM
fnp-3025	1594	2	):	):	PUNCT
fnp-3025	1594	3	p.	p.	NOUN
fnp-3025	1594	4	5991	5991	NUM
fnp-3025	1594	5	-	-	SYM
fnp-3025	1594	6	4	4	NUM
fnp-3025	1594	7	.	.	NUM
fnp-3025	1594	8	252	252	NUM
fnp-3025	1594	9	.	.	PUNCT
fnp-3025	1595	1	natte	natte	PROPN
fnp-3025	1595	2	,	,	PUNCT
fnp-3025	1595	3	r.	r.	PROPN
fnp-3025	1595	4	,	,	PUNCT
fnp-3025	1595	5	et	et	PROPN
fnp-3025	1595	6	al	al	PROPN
fnp-3025	1595	7	.	.	PROPN
fnp-3025	1595	8	,	,	PUNCT
fnp-3025	1595	9	dementia	dementia	NOUN
fnp-3025	1595	10	in	in	ADP
fnp-3025	1595	11	hereditary	hereditary	ADJ
fnp-3025	1595	12	cerebral	cerebral	ADJ
fnp-3025	1595	13	hemorrhage	hemorrhage	NOUN
fnp-3025	1595	14	with	with	ADP
fnp-3025	1595	15	amyloidosis	amyloidosis	NOUN
fnp-3025	1595	16	-	-	PUNCT
fnp-3025	1595	17	dutch	dutch	NOUN
fnp-3025	1595	18	type	type	NOUN
fnp-3025	1595	19	is	be	AUX
fnp-3025	1595	20	associated	associate	VERB
fnp-3025	1595	21	with	with	ADP
fnp-3025	1595	22	cerebral	cerebral	ADJ
fnp-3025	1595	23	amyloid	amyloid	NOUN
fnp-3025	1595	24	angiopathy	angiopathy	NOUN
fnp-3025	1595	25	but	but	CCONJ
fnp-3025	1595	26	is	be	AUX
fnp-3025	1595	27	independent	independent	ADJ
fnp-3025	1595	28	of	of	ADP
fnp-3025	1595	29	plaques	plaque	NOUN
fnp-3025	1595	30	and	and	CCONJ
fnp-3025	1595	31	neurofibrillary	neurofibrillary	ADJ
fnp-3025	1595	32	tangles	tangle	NOUN
fnp-3025	1595	33	.	.	PUNCT
fnp-3025	1596	1	ann	ann	PROPN
fnp-3025	1596	2	neurol	neurol	PROPN
fnp-3025	1596	3	,	,	PUNCT
fnp-3025	1596	4	2001	2001	NUM
fnp-3025	1596	5	.	.	PUNCT
fnp-3025	1597	1	50(6	50(6	NUM
fnp-3025	1597	2	):	):	PUNCT
fnp-3025	1598	1	p.	p.	NOUN
fnp-3025	1598	2	765	765	NUM
fnp-3025	1598	3	-	-	SYM
fnp-3025	1598	4	72	72	NUM
fnp-3025	1598	5	.	.	PUNCT
fnp-3025	1598	6	253	253	NUM
fnp-3025	1598	7	.	.	X
fnp-3025	1599	1	wattendorff	wattendorff	NOUN
fnp-3025	1599	2	,	,	PUNCT
fnp-3025	1599	3	a.r	a.r	PROPN
fnp-3025	1599	4	.	.	PROPN
fnp-3025	1599	5	,	,	PUNCT
fnp-3025	1599	6	et	et	PROPN
fnp-3025	1599	7	al	al	PROPN
fnp-3025	1599	8	.	.	PROPN
fnp-3025	1599	9	,	,	PUNCT
fnp-3025	1599	10	hereditary	hereditary	ADJ
fnp-3025	1599	11	cerebral	cerebral	ADJ
fnp-3025	1599	12	haemorrhage	haemorrhage	NOUN
fnp-3025	1599	13	with	with	ADP
fnp-3025	1599	14	amyloidosis	amyloidosis	NOUN
fnp-3025	1599	15	,	,	PUNCT
fnp-3025	1599	16	dutch	dutch	ADJ
fnp-3025	1599	17	type	type	NOUN
fnp-3025	1599	18	(	(	PUNCT
fnp-3025	1599	19	hchwa	hchwa	PROPN
fnp-3025	1599	20	-	-	PUNCT
fnp-3025	1599	21	d	d	PROPN
fnp-3025	1599	22	):	):	PUNCT
fnp-3025	1599	23	clinicopathological	clinicopathological	ADJ
fnp-3025	1599	24	studies	study	NOUN
fnp-3025	1599	25	.	.	PUNCT
fnp-3025	1600	1	j	j	PROPN
fnp-3025	1600	2	neurol	neurol	PROPN
fnp-3025	1600	3	neurosurg	neurosurg	PROPN
fnp-3025	1600	4	psychiatry	psychiatry	PROPN
fnp-3025	1600	5	,	,	PUNCT
fnp-3025	1600	6	1995	1995	NUM
fnp-3025	1600	7	.	.	PUNCT
fnp-3025	1601	1	58(6	58(6	NUM
fnp-3025	1601	2	):	):	PUNCT
fnp-3025	1602	1	p.	p.	NOUN
fnp-3025	1602	2	699	699	NUM
fnp-3025	1602	3	-	-	SYM
fnp-3025	1602	4	705	705	NUM
fnp-3025	1602	5	.	.	PUNCT
fnp-3025	1602	6	254	254	NUM
fnp-3025	1602	7	.	.	PUNCT
fnp-3025	1603	1	case	case	NOUN
fnp-3025	1603	2	,	,	PUNCT
fnp-3025	1603	3	n.f	n.f	PROPN
fnp-3025	1603	4	.	.	PROPN
fnp-3025	1603	5	,	,	PUNCT
fnp-3025	1603	6	et	et	PROPN
fnp-3025	1603	7	al	al	PROPN
fnp-3025	1603	8	.	.	PROPN
fnp-3025	1603	9	,	,	PUNCT
fnp-3025	1603	10	cerebral	cerebral	ADJ
fnp-3025	1603	11	amyloid	amyloid	NOUN
fnp-3025	1603	12	angiopathy	angiopathy	NOUN
fnp-3025	1603	13	is	be	AUX
fnp-3025	1603	14	associated	associate	VERB
fnp-3025	1603	15	with	with	ADP
fnp-3025	1603	16	executive	executive	ADJ
fnp-3025	1603	17	dysfunction	dysfunction	NOUN
fnp-3025	1603	18	and	and	CCONJ
fnp-3025	1603	19	mild	mild	ADJ
fnp-3025	1603	20	cognitive	cognitive	ADJ
fnp-3025	1603	21	impairment	impairment	NOUN
fnp-3025	1603	22	.	.	PUNCT
fnp-3025	1604	1	stroke	stroke	NOUN
fnp-3025	1604	2	,	,	PUNCT
fnp-3025	1604	3	2016	2016	NUM
fnp-3025	1604	4	.	.	PUNCT
fnp-3025	1605	1	47(8	47(8	NOUN
fnp-3025	1605	2	):	):	PUNCT
fnp-3025	1605	3	p.	p.	NOUN
fnp-3025	1605	4	2010	2010	NUM
fnp-3025	1605	5	-	-	SYM
fnp-3025	1605	6	6	6	NUM
fnp-3025	1605	7	.	.	NUM
fnp-3025	1605	8	255	255	NUM
fnp-3025	1605	9	.	.	PUNCT
fnp-3025	1606	1	pfeifer	pfeifer	PROPN
fnp-3025	1606	2	,	,	PUNCT
fnp-3025	1606	3	l.a	l.a	PROPN
fnp-3025	1606	4	.	.	PROPN
fnp-3025	1606	5	,	,	PUNCT
fnp-3025	1606	6	et	et	PROPN
fnp-3025	1606	7	al	al	PROPN
fnp-3025	1606	8	.	.	PROPN
fnp-3025	1606	9	,	,	PUNCT
fnp-3025	1606	10	cerebral	cerebral	ADJ
fnp-3025	1606	11	amyloid	amyloid	NOUN
fnp-3025	1606	12	angiopathy	angiopathy	ADJ
fnp-3025	1606	13	and	and	CCONJ
fnp-3025	1606	14	cognitive	cognitive	ADJ
fnp-3025	1606	15	function	function	NOUN
fnp-3025	1606	16	:	:	PUNCT
fnp-3025	1606	17	the	the	DET
fnp-3025	1606	18	haas	haas	PROPN
fnp-3025	1606	19	autopsy	autopsy	ADJ
fnp-3025	1606	20	study	study	NOUN
fnp-3025	1606	21	.	.	PUNCT
fnp-3025	1607	1	neurology	neurology	NOUN
fnp-3025	1607	2	,	,	PUNCT
fnp-3025	1607	3	2002	2002	NUM
fnp-3025	1607	4	.	.	PUNCT
fnp-3025	1608	1	58(11	58(11	NUM
fnp-3025	1608	2	):	):	PUNCT
fnp-3025	1608	3	p.	p.	NOUN
fnp-3025	1608	4	1629	1629	NUM
fnp-3025	1608	5	-	-	SYM
fnp-3025	1608	6	34	34	NUM
fnp-3025	1608	7	.	.	NOUN
fnp-3025	1609	1	256	256	NUM
fnp-3025	1609	2	.	.	X
fnp-3025	1609	3	schrag	schrag	NOUN
fnp-3025	1609	4	,	,	PUNCT
fnp-3025	1609	5	m.	m.	NOUN
fnp-3025	1609	6	and	and	CCONJ
fnp-3025	1609	7	h.	h.	PROPN
fnp-3025	1609	8	kirshner	kirshner	PROPN
fnp-3025	1609	9	,	,	PUNCT
fnp-3025	1609	10	neuropsychological	neuropsychological	ADJ
fnp-3025	1609	11	effects	effect	NOUN
fnp-3025	1609	12	of	of	ADP
fnp-3025	1609	13	cerebral	cerebral	ADJ
fnp-3025	1609	14	amyloid	amyloid	NOUN
fnp-3025	1609	15	angiopathy	angiopathy	NOUN
fnp-3025	1609	16	.	.	PUNCT
fnp-3025	1610	1	curr	curr	PROPN
fnp-3025	1610	2	neurol	neurol	PROPN
fnp-3025	1610	3	neurosci	neurosci	PROPN
fnp-3025	1610	4	rep	rep	PROPN
fnp-3025	1610	5	,	,	PUNCT
fnp-3025	1610	6	2016	2016	NUM
fnp-3025	1610	7	.	.	PUNCT
fnp-3025	1611	1	16(8	16(8	NUM
fnp-3025	1611	2	):	):	PUNCT
fnp-3025	1611	3	p.	p.	NOUN
fnp-3025	1611	4	76	76	NUM
fnp-3025	1611	5	.	.	PUNCT
fnp-3025	1612	1	257	257	NUM
fnp-3025	1612	2	.	.	PUNCT
fnp-3025	1613	1	thal	thal	PROPN
fnp-3025	1613	2	,	,	PUNCT
fnp-3025	1613	3	d.r	d.r	PROPN
fnp-3025	1613	4	.	.	PROPN
fnp-3025	1613	5	,	,	PUNCT
fnp-3025	1613	6	et	et	PROPN
fnp-3025	1613	7	al	al	PROPN
fnp-3025	1613	8	.	.	PROPN
fnp-3025	1613	9	,	,	PUNCT
fnp-3025	1613	10	vascular	vascular	ADJ
fnp-3025	1613	11	pathology	pathology	NOUN
fnp-3025	1613	12	in	in	ADP
fnp-3025	1613	13	alzheimer	alzheimer	PROPN
fnp-3025	1613	14	disease	disease	PROPN
fnp-3025	1613	15	:	:	PUNCT
fnp-3025	1613	16	correlation	correlation	NOUN
fnp-3025	1613	17	of	of	ADP
fnp-3025	1613	18	cerebral	cerebral	ADJ
fnp-3025	1613	19	amyloid	amyloid	NOUN
fnp-3025	1613	20	angiopathy	angiopathy	NOUN
fnp-3025	1613	21	and	and	CCONJ
fnp-3025	1613	22	arteriosclerosis	arteriosclerosis	NOUN
fnp-3025	1613	23	/	/	SYM
fnp-3025	1613	24	lipohyalinosis	lipohyalinosis	NOUN
fnp-3025	1613	25	with	with	ADP
fnp-3025	1613	26	cognitive	cognitive	ADJ
fnp-3025	1613	27	decline	decline	NOUN
fnp-3025	1613	28	.	.	PUNCT
fnp-3025	1614	1	j	j	PROPN
fnp-3025	1614	2	neuropathol	neuropathol	PROPN
fnp-3025	1614	3	exp	exp	PROPN
fnp-3025	1614	4	neurol	neurol	PROPN
fnp-3025	1614	5	,	,	PUNCT
fnp-3025	1614	6	2003	2003	NUM
fnp-3025	1614	7	.	.	PUNCT
fnp-3025	1615	1	62(12	62(12	NUM
fnp-3025	1615	2	):	):	PUNCT
fnp-3025	1615	3	p.	p.	NOUN
fnp-3025	1615	4	1287	1287	NUM
fnp-3025	1615	5	-	-	SYM
fnp-3025	1615	6	301	301	NUM
fnp-3025	1615	7	.	.	PUNCT
fnp-3025	1615	8	258	258	NUM
fnp-3025	1615	9	.	.	PUNCT
fnp-3025	1616	1	xiong	xiong	PROPN
fnp-3025	1616	2	,	,	PUNCT
fnp-3025	1616	3	l.	l.	PROPN
fnp-3025	1616	4	,	,	PUNCT
fnp-3025	1616	5	et	et	PROPN
fnp-3025	1616	6	al	al	PROPN
fnp-3025	1616	7	.	.	PROPN
fnp-3025	1616	8	,	,	PUNCT
fnp-3025	1616	9	dementia	dementia	NOUN
fnp-3025	1616	10	incidence	incidence	NOUN
fnp-3025	1616	11	and	and	CCONJ
fnp-3025	1616	12	predictors	predictor	NOUN
fnp-3025	1616	13	in	in	ADP
fnp-3025	1616	14	cerebral	cerebral	ADJ
fnp-3025	1616	15	amyloid	amyloid	NOUN
fnp-3025	1616	16	angiopathy	angiopathy	ADJ
fnp-3025	1616	17	patients	patient	NOUN
fnp-3025	1616	18	without	without	ADP
fnp-3025	1616	19	intracerebral	intracerebral	ADJ
fnp-3025	1616	20	hemorrhage	hemorrhage	NOUN
fnp-3025	1616	21	.	.	PUNCT
fnp-3025	1617	1	j	j	PROPN
fnp-3025	1617	2	cereb	cereb	PROPN
fnp-3025	1617	3	blood	blood	PROPN
fnp-3025	1617	4	flow	flow	NOUN
fnp-3025	1617	5	metab	metab	NOUN
fnp-3025	1617	6	,	,	PUNCT
fnp-3025	1617	7	2018	2018	NUM
fnp-3025	1617	8	.	.	PUNCT
fnp-3025	1618	1	38(2	38(2	NUM
fnp-3025	1618	2	):	):	PUNCT
fnp-3025	1618	3	p.	p.	NOUN
fnp-3025	1618	4	241	241	NUM
fnp-3025	1618	5	-	-	PROPN
fnp-3025	1618	6	249	249	NUM
fnp-3025	1618	7	.	.	PUNCT
fnp-3025	1619	1	259	259	NUM
fnp-3025	1619	2	.	.	X
fnp-3025	1620	1	smith	smith	PROPN
fnp-3025	1620	2	,	,	PUNCT
fnp-3025	1620	3	e.e	e.e	PROPN
fnp-3025	1620	4	.	.	PROPN
fnp-3025	1620	5	,	,	PUNCT
fnp-3025	1620	6	cerebral	cerebral	ADJ
fnp-3025	1620	7	amyloid	amyloid	NOUN
fnp-3025	1620	8	angiopathy	angiopathy	NOUN
fnp-3025	1620	9	as	as	ADP
fnp-3025	1620	10	a	a	DET
fnp-3025	1620	11	cause	cause	NOUN
fnp-3025	1620	12	of	of	ADP
fnp-3025	1620	13	neurodegeneration	neurodegeneration	NOUN
fnp-3025	1620	14	.	.	PUNCT
fnp-3025	1621	1	j	j	PROPN
fnp-3025	1621	2	neurochem	neurochem	PROPN
fnp-3025	1621	3	,	,	PUNCT
fnp-3025	1621	4	2018	2018	NUM
fnp-3025	1621	5	.	.	PUNCT
fnp-3025	1622	1	144(5	144(5	NUM
fnp-3025	1622	2	):	):	PUNCT
fnp-3025	1623	1	p.	p.	NOUN
fnp-3025	1623	2	651	651	NUM
fnp-3025	1623	3	-	-	SYM
fnp-3025	1623	4	658	658	NUM
fnp-3025	1623	5	.	.	NOUN
fnp-3025	1623	6	260	260	NUM
fnp-3025	1623	7	.	.	PUNCT
fnp-3025	1624	1	cisternas	cisterna	NOUN
fnp-3025	1624	2	,	,	PUNCT
fnp-3025	1624	3	p.	p.	PROPN
fnp-3025	1624	4	,	,	PUNCT
fnp-3025	1624	5	x.	x.	PROPN
fnp-3025	1624	6	taylor	taylor	PROPN
fnp-3025	1624	7	,	,	PUNCT
fnp-3025	1624	8	and	and	CCONJ
fnp-3025	1624	9	c.a	c.a	PROPN
fnp-3025	1624	10	.	.	PROPN
fnp-3025	1624	11	lasagna	lasagna	PROPN
fnp-3025	1624	12	-	-	PUNCT
fnp-3025	1624	13	reeves	reeves	PROPN
fnp-3025	1624	14	,	,	PUNCT
fnp-3025	1624	15	the	the	DET
fnp-3025	1624	16	amyloid	amyloid	NOUN
fnp-3025	1624	17	-	-	PUNCT
fnp-3025	1624	18	tau	tau	NOUN
fnp-3025	1624	19	-	-	PUNCT
fnp-3025	1624	20	neuroinflammation	neuroinflammation	NOUN
fnp-3025	1624	21	axis	axis	NOUN
fnp-3025	1624	22	in	in	ADP
fnp-3025	1624	23	the	the	DET
fnp-3025	1624	24	context	context	NOUN
fnp-3025	1624	25	of	of	ADP
fnp-3025	1624	26	cerebral	cerebral	ADJ
fnp-3025	1624	27	amyloid	amyloid	NOUN
fnp-3025	1624	28	angiopathy	angiopathy	NOUN
fnp-3025	1624	29	.	.	PUNCT
fnp-3025	1625	1	int	int	PROPN
fnp-3025	1625	2	j	j	PROPN
fnp-3025	1625	3	mol	mol	ADP
fnp-3025	1625	4	sci	sci	PROPN
fnp-3025	1625	5	,	,	PUNCT
fnp-3025	1625	6	2019	2019	NUM
fnp-3025	1625	7	.	.	PUNCT
fnp-3025	1626	1	20(24	20(24	NUM
fnp-3025	1626	2	):	):	PUNCT
fnp-3025	1626	3	p.	p.	NOUN
fnp-3025	1626	4	6319	6319	NUM
fnp-3025	1626	5	.	.	PUNCT
fnp-3025	1627	1	261	261	NUM
fnp-3025	1627	2	.	.	PUNCT
fnp-3025	1628	1	grabowski	grabowski	PROPN
fnp-3025	1628	2	,	,	PUNCT
fnp-3025	1628	3	t.j	t.j	PROPN
fnp-3025	1628	4	.	.	PROPN
fnp-3025	1628	5	,	,	PUNCT
fnp-3025	1628	6	et	et	PROPN
fnp-3025	1628	7	al	al	PROPN
fnp-3025	1628	8	.	.	PROPN
fnp-3025	1628	9	,	,	PUNCT
fnp-3025	1628	10	novel	novel	ADJ
fnp-3025	1628	11	amyloid	amyloid	NOUN
fnp-3025	1628	12	precursor	precursor	NOUN
fnp-3025	1628	13	protein	protein	NOUN
fnp-3025	1628	14	mutation	mutation	NOUN
fnp-3025	1628	15	in	in	ADP
fnp-3025	1628	16	an	an	DET
fnp-3025	1628	17	iowa	iowa	PROPN
fnp-3025	1628	18	family	family	NOUN
fnp-3025	1628	19	with	with	ADP
fnp-3025	1628	20	dementia	dementia	NOUN
fnp-3025	1628	21	and	and	CCONJ
fnp-3025	1628	22	severe	severe	ADJ
fnp-3025	1628	23	cerebral	cerebral	ADJ
fnp-3025	1628	24	amyloid	amyloid	NOUN
fnp-3025	1628	25	angiopathy	angiopathy	NOUN
fnp-3025	1628	26	.	.	PUNCT
fnp-3025	1629	1	ann	ann	PROPN
fnp-3025	1629	2	neurol	neurol	PROPN
fnp-3025	1629	3	,	,	PUNCT
fnp-3025	1629	4	2001	2001	NUM
fnp-3025	1629	5	.	.	PUNCT
fnp-3025	1630	1	49(6	49(6	NUM
fnp-3025	1630	2	):	):	PUNCT
fnp-3025	1631	1	p.	p.	NOUN
fnp-3025	1631	2	697	697	NUM
fnp-3025	1631	3	-	-	SYM
fnp-3025	1631	4	705	705	NUM
fnp-3025	1631	5	.	.	PUNCT
fnp-3025	1631	6	262	262	NUM
fnp-3025	1631	7	.	.	PUNCT
fnp-3025	1632	1	oshima	oshima	PROPN
fnp-3025	1632	2	,	,	PUNCT
fnp-3025	1632	3	k.	k.	PROPN
fnp-3025	1632	4	,	,	PUNCT
fnp-3025	1632	5	et	et	PROPN
fnp-3025	1632	6	al	al	PROPN
fnp-3025	1632	7	.	.	PROPN
fnp-3025	1632	8	,	,	PUNCT
fnp-3025	1632	9	relative	relative	ADJ
fnp-3025	1632	10	paucity	paucity	NOUN
fnp-3025	1632	11	of	of	ADP
fnp-3025	1632	12	tau	tau	PROPN
fnp-3025	1632	13	accumulation	accumulation	NOUN
fnp-3025	1632	14	in	in	ADP
fnp-3025	1632	15	the	the	DET
fnp-3025	1632	16	small	small	ADJ
fnp-3025	1632	17	areas	area	NOUN
fnp-3025	1632	18	with	with	ADP
fnp-3025	1632	19	abundant	abundant	ADJ
fnp-3025	1632	20	abeta42	abeta42	NOUN
fnp-3025	1632	21	-	-	PUNCT
fnp-3025	1632	22	positive	positive	ADJ
fnp-3025	1632	23	capillary	capillary	ADJ
fnp-3025	1632	24	amyloid	amyloid	NOUN
fnp-3025	1632	25	angiopathy	angiopathy	NOUN
fnp-3025	1632	26	within	within	ADP
fnp-3025	1632	27	a	a	DET
fnp-3025	1632	28	given	give	VERB
fnp-3025	1632	29	cortical	cortical	ADJ
fnp-3025	1632	30	region	region	NOUN
fnp-3025	1632	31	in	in	ADP
fnp-3025	1632	32	the	the	DET
fnp-3025	1632	33	brain	brain	NOUN
fnp-3025	1632	34	of	of	ADP
fnp-3025	1632	35	patients	patient	NOUN
fnp-3025	1632	36	with	with	ADP
fnp-3025	1632	37	alzheimer	alzheimer	PROPN
fnp-3025	1632	38	pathology	pathology	PROPN
fnp-3025	1632	39	.	.	PUNCT
fnp-3025	1633	1	acta	acta	PROPN
fnp-3025	1633	2	neuropathol	neuropathol	PROPN
fnp-3025	1633	3	,	,	PUNCT
fnp-3025	1633	4	2006	2006	NUM
fnp-3025	1633	5	.	.	PUNCT
fnp-3025	1634	1	111(6	111(6	NUM
fnp-3025	1634	2	):	):	PUNCT
fnp-3025	1635	1	p.	p.	NOUN
fnp-3025	1635	2	510	510	NUM
fnp-3025	1635	3	-	-	SYM
fnp-3025	1635	4	8	8	NUM
fnp-3025	1635	5	.	.	PUNCT
fnp-3025	1635	6	263	263	NUM
fnp-3025	1635	7	.	.	PUNCT
fnp-3025	1636	1	yamaguchi	yamaguchi	PROPN
fnp-3025	1636	2	,	,	PUNCT
fnp-3025	1636	3	h.	h.	PROPN
fnp-3025	1636	4	and	and	CCONJ
fnp-3025	1636	5	m.l.c	m.l.c	ADJ
fnp-3025	1636	6	.	.	PUNCT
fnp-3025	1636	7	maat	maat	PROPN
fnp-3025	1636	8	-	-	PUNCT
fnp-3025	1636	9	schieman	schieman	NOUN
fnp-3025	1636	10	,	,	PUNCT
fnp-3025	1636	11	immunohistochemical	immunohistochemical	ADJ
fnp-3025	1636	12	analysis	analysis	NOUN
fnp-3025	1636	13	of	of	ADP
fnp-3025	1636	14	amyloid	amyloid	NOUN
fnp-3025	1636	15	beta	beta	NOUN
fnp-3025	1636	16	-	-	PUNCT
fnp-3025	1636	17	protein	protein	NOUN
fnp-3025	1636	18	isoforms	isoform	NOUN
fnp-3025	1636	19	in	in	ADP
fnp-3025	1636	20	caa	caa	NOUN
fnp-3025	1636	21	,	,	PUNCT
fnp-3025	1636	22	in	in	ADP
fnp-3025	1636	23	cerebral	cerebral	ADJ
fnp-3025	1636	24	amyloid	amyloid	NOUN
fnp-3025	1636	25	angiopathy	angiopathy	NOUN
fnp-3025	1636	26	in	in	ADP
fnp-3025	1636	27	alzheimer	alzheimer	PROPN
fnp-3025	1636	28	’s	’s	PART
fnp-3025	1636	29	disease	disease	NOUN
fnp-3025	1636	30	and	and	CCONJ
fnp-3025	1636	31	related	related	ADJ
fnp-3025	1636	32	disorders	disorder	NOUN
fnp-3025	1636	33	,	,	PUNCT
fnp-3025	1636	34	m.m	m.m	PROPN
fnp-3025	1636	35	.	.	PROPN
fnp-3025	1636	36	verbeek	verbeek	PROPN
fnp-3025	1636	37	,	,	PUNCT
fnp-3025	1636	38	r.m.w	r.m.w	PROPN
fnp-3025	1636	39	.	.	PUNCT
fnp-3025	1636	40	de	de	X
fnp-3025	1636	41	waal	waal	PROPN
fnp-3025	1636	42	,	,	PUNCT
fnp-3025	1636	43	and	and	CCONJ
fnp-3025	1636	44	h.v	h.v	PROPN
fnp-3025	1636	45	.	.	PROPN
fnp-3025	1636	46	vinters	vinter	NOUN
fnp-3025	1636	47	,	,	PUNCT
fnp-3025	1636	48	editors	editor	NOUN
fnp-3025	1636	49	.	.	PUNCT
fnp-3025	1636	50	2000	2000	NUM
fnp-3025	1636	51	,	,	PUNCT
fnp-3025	1636	52	kluwer	kluwer	NOUN
fnp-3025	1636	53	academic	academic	ADJ
fnp-3025	1636	54	publishers	publisher	NOUN
fnp-3025	1636	55	:	:	PUNCT
fnp-3025	1636	56	dordrecht	dordrecht	PROPN
fnp-3025	1636	57	.	.	PUNCT
fnp-3025	1637	1	p.	p.	NOUN
fnp-3025	1637	2	179	179	NUM
fnp-3025	1638	1	-	-	SYM
fnp-3025	1638	2	188	188	NUM
fnp-3025	1638	3	.	.	PUNCT
fnp-3025	1639	1	264	264	NUM
fnp-3025	1639	2	.	.	PUNCT
fnp-3025	1640	1	roher	roher	PROPN
fnp-3025	1640	2	,	,	PUNCT
fnp-3025	1640	3	a.e	a.e	PROPN
fnp-3025	1640	4	.	.	PROPN
fnp-3025	1640	5	,	,	PUNCT
fnp-3025	1640	6	et	et	PROPN
fnp-3025	1640	7	al	al	PROPN
fnp-3025	1640	8	.	.	PROPN
fnp-3025	1640	9	,	,	PUNCT
fnp-3025	1640	10	chemical	chemical	ADJ
fnp-3025	1640	11	analysis	analysis	NOUN
fnp-3025	1640	12	of	of	ADP
fnp-3025	1640	13	amyloid	amyloid	NOUN
fnp-3025	1640	14	beta	beta	NOUN
fnp-3025	1640	15	protein	protein	NOUN
fnp-3025	1640	16	in	in	ADP
fnp-3025	1640	17	caa	caa	NOUN
fnp-3025	1640	18	,	,	PUNCT
fnp-3025	1640	19	in	in	ADP
fnp-3025	1640	20	cerebral	cerebral	ADJ
fnp-3025	1640	21	amyloid	amyloid	NOUN
fnp-3025	1640	22	angiopathy	angiopathy	NOUN
fnp-3025	1640	23	in	in	ADP
fnp-3025	1640	24	alzheimer	alzheimer	PROPN
fnp-3025	1640	25	’s	’s	PART
fnp-3025	1640	26	disease	disease	NOUN
fnp-3025	1640	27	and	and	CCONJ
fnp-3025	1640	28	related	related	ADJ
fnp-3025	1640	29	disorders	disorder	NOUN
fnp-3025	1640	30	,	,	PUNCT
fnp-3025	1640	31	m.m	m.m	PROPN
fnp-3025	1640	32	.	.	PROPN
fnp-3025	1640	33	verbeek	verbeek	PROPN
fnp-3025	1640	34	,	,	PUNCT
fnp-3025	1640	35	r.m.w	r.m.w	PROPN
fnp-3025	1640	36	.	.	PUNCT
fnp-3025	1640	37	de	de	X
fnp-3025	1640	38	waal	waal	PROPN
fnp-3025	1640	39	,	,	PUNCT
fnp-3025	1640	40	and	and	CCONJ
fnp-3025	1640	41	h.v	h.v	PROPN
fnp-3025	1640	42	.	.	PROPN
fnp-3025	1640	43	vinters	vinter	NOUN
fnp-3025	1640	44	,	,	PUNCT
fnp-3025	1640	45	editors	editor	NOUN
fnp-3025	1640	46	.	.	PUNCT
fnp-3025	1641	1	2000	2000	NUM
fnp-3025	1641	2	,	,	PUNCT
fnp-3025	1641	3	kluwer	kluwer	NOUN
fnp-3025	1641	4	academic	academic	ADJ
fnp-3025	1641	5	publishers	publisher	NOUN
fnp-3025	1641	6	:	:	PUNCT
fnp-3025	1641	7	dordrecht	dordrecht	PROPN
fnp-3025	1641	8	.	.	PUNCT
fnp-3025	1642	1	p.	p.	NOUN
fnp-3025	1642	2	157	157	NUM
fnp-3025	1643	1	-	-	SYM
fnp-3025	1643	2	177	177	NUM
fnp-3025	1643	3	.	.	PUNCT
fnp-3025	1644	1	265	265	NUM
fnp-3025	1644	2	.	.	PUNCT
fnp-3025	1645	1	kawai	kawai	PROPN
fnp-3025	1645	2	,	,	PUNCT
fnp-3025	1645	3	m.	m.	NOUN
fnp-3025	1645	4	,	,	PUNCT
fnp-3025	1645	5	et	et	PROPN
fnp-3025	1645	6	al	al	PROPN
fnp-3025	1645	7	.	.	PROPN
fnp-3025	1645	8	,	,	PUNCT
fnp-3025	1645	9	the	the	DET
fnp-3025	1645	10	relationship	relationship	NOUN
fnp-3025	1645	11	of	of	ADP
fnp-3025	1645	12	amyloid	amyloid	NOUN
fnp-3025	1645	13	plaques	plaque	NOUN
fnp-3025	1645	14	to	to	ADP
fnp-3025	1645	15	cerebral	cerebral	ADJ
fnp-3025	1645	16	capillaries	capillary	NOUN
fnp-3025	1645	17	in	in	ADP
fnp-3025	1645	18	alzheimer	alzheimer	PROPN
fnp-3025	1645	19	’s	’s	PART
fnp-3025	1645	20	disease	disease	NOUN
fnp-3025	1645	21	.	.	PUNCT
fnp-3025	1646	1	am	be	AUX
fnp-3025	1646	2	j	j	PROPN
fnp-3025	1646	3	pathol	pathol	NOUN
fnp-3025	1646	4	,	,	PUNCT
fnp-3025	1646	5	1990	1990	NUM
fnp-3025	1646	6	.	.	PUNCT
fnp-3025	1647	1	137(6	137(6	NUM
fnp-3025	1647	2	):	):	PUNCT
fnp-3025	1647	3	p.	p.	NOUN
fnp-3025	1647	4	1435	1435	NUM
fnp-3025	1647	5	-	-	SYM
fnp-3025	1647	6	46	46	NUM
fnp-3025	1647	7	.	.	PUNCT
fnp-3025	1647	8	266	266	NUM
fnp-3025	1647	9	.	.	PUNCT
fnp-3025	1648	1	vinters	vinter	NOUN
fnp-3025	1648	2	,	,	PUNCT
fnp-3025	1648	3	h.v	h.v	PROPN
fnp-3025	1648	4	.	.	PROPN
fnp-3025	1648	5	,	,	PUNCT
fnp-3025	1648	6	cerebral	cerebral	ADJ
fnp-3025	1648	7	amyloid	amyloid	NOUN
fnp-3025	1648	8	angiopathy	angiopathy	NOUN
fnp-3025	1648	9	.	.	PUNCT
fnp-3025	1649	1	a	a	DET
fnp-3025	1649	2	critical	critical	ADJ
fnp-3025	1649	3	review	review	NOUN
fnp-3025	1649	4	.	.	PUNCT
fnp-3025	1650	1	stroke	stroke	NOUN
fnp-3025	1650	2	,	,	PUNCT
fnp-3025	1650	3	1987	1987	NUM
fnp-3025	1650	4	.	.	PUNCT
fnp-3025	1651	1	18(2	18(2	NUM
fnp-3025	1651	2	):	):	PUNCT
fnp-3025	1651	3	p.	p.	NOUN
fnp-3025	1651	4	311	311	NUM
fnp-3025	1651	5	-	-	SYM
fnp-3025	1651	6	24	24	NUM
fnp-3025	1651	7	.	.	PUNCT
fnp-3025	1652	1	267	267	NUM
fnp-3025	1652	2	.	.	X
fnp-3025	1652	3	de	de	PROPN
fnp-3025	1652	4	waal	waal	PROPN
fnp-3025	1652	5	,	,	PUNCT
fnp-3025	1652	6	r.m.w	r.m.w	PROPN
fnp-3025	1652	7	.	.	PUNCT
fnp-3025	1652	8	and	and	CCONJ
fnp-3025	1652	9	m.m	m.m	PROPN
fnp-3025	1652	10	.	.	PROPN
fnp-3025	1652	11	verbeek	verbeek	PROPN
fnp-3025	1652	12	,	,	PUNCT
fnp-3025	1652	13	abeta	abeta	ADJ
fnp-3025	1652	14	-	-	PUNCT
fnp-3025	1652	15	associated	associate	VERB
fnp-3025	1652	16	proteins	protein	NOUN
fnp-3025	1652	17	in	in	ADP
fnp-3025	1652	18	cerebral	cerebral	ADJ
fnp-3025	1652	19	amyloid	amyloid	NOUN
fnp-3025	1652	20	angiopathy	angiopathy	NOUN
fnp-3025	1652	21	,	,	PUNCT
fnp-3025	1652	22	in	in	ADP
fnp-3025	1652	23	cerebral	cerebral	ADJ
fnp-3025	1652	24	amyloid	amyloid	NOUN
fnp-3025	1652	25	angiopathy	angiopathy	NOUN
fnp-3025	1652	26	in	in	ADP
fnp-3025	1652	27	alzheimer	alzheimer	PROPN
fnp-3025	1652	28	’s	’s	PART
fnp-3025	1652	29	disease	disease	NOUN
fnp-3025	1652	30	and	and	CCONJ
fnp-3025	1652	31	related	related	ADJ
fnp-3025	1652	32	disorders	disorder	NOUN
fnp-3025	1652	33	,	,	PUNCT
fnp-3025	1652	34	m.m	m.m	PROPN
fnp-3025	1652	35	.	.	PROPN
fnp-3025	1652	36	verbeek	verbeek	PROPN
fnp-3025	1652	37	,	,	PUNCT
fnp-3025	1652	38	r.m.w	r.m.w	PROPN
fnp-3025	1652	39	.	.	PUNCT
fnp-3025	1652	40	de	de	X
fnp-3025	1652	41	waal	waal	PROPN
fnp-3025	1652	42	,	,	PUNCT
fnp-3025	1652	43	and	and	CCONJ
fnp-3025	1652	44	h.v	h.v	PROPN
fnp-3025	1652	45	.	.	PROPN
fnp-3025	1652	46	vinters	vinter	NOUN
fnp-3025	1652	47	,	,	PUNCT
fnp-3025	1652	48	editors	editor	NOUN
fnp-3025	1652	49	.	.	PUNCT
fnp-3025	1653	1	2000	2000	NUM
fnp-3025	1653	2	,	,	PUNCT
fnp-3025	1653	3	kluwer	kluwer	NOUN
fnp-3025	1653	4	academic	academic	ADJ
fnp-3025	1653	5	publishers	publisher	NOUN
fnp-3025	1653	6	:	:	PUNCT
fnp-3025	1653	7	dordrecht	dordrecht	PROPN
fnp-3025	1653	8	.	.	PUNCT
fnp-3025	1654	1	p.	p.	NOUN
fnp-3025	1654	2	207	207	NUM
fnp-3025	1654	3	-	-	SYM
fnp-3025	1654	4	221	221	NUM
fnp-3025	1654	5	.	.	PUNCT
fnp-3025	1654	6	268	268	NUM
fnp-3025	1654	7	.	.	PUNCT
fnp-3025	1655	1	boche	boche	PROPN
fnp-3025	1655	2	,	,	PUNCT
fnp-3025	1655	3	d.	d.	PROPN
fnp-3025	1655	4	,	,	PUNCT
fnp-3025	1655	5	et	et	PROPN
fnp-3025	1655	6	al	al	PROPN
fnp-3025	1655	7	.	.	PROPN
fnp-3025	1655	8	,	,	PUNCT
fnp-3025	1655	9	consequence	consequence	NOUN
fnp-3025	1655	10	of	of	ADP
fnp-3025	1655	11	abeta	abeta	ADJ
fnp-3025	1655	12	immunization	immunization	NOUN
fnp-3025	1655	13	on	on	ADP
fnp-3025	1655	14	the	the	DET
fnp-3025	1655	15	vasculature	vasculature	NOUN
fnp-3025	1655	16	of	of	ADP
fnp-3025	1655	17	human	human	PROPN
fnp-3025	1655	18	alzheimer	alzheimer	PROPN
fnp-3025	1655	19	’s	’s	PART
fnp-3025	1655	20	disease	disease	NOUN
fnp-3025	1655	21	brain	brain	NOUN
fnp-3025	1655	22	.	.	PUNCT
fnp-3025	1656	1	brain	brain	NOUN
fnp-3025	1656	2	,	,	PUNCT
fnp-3025	1656	3	2008	2008	NUM
fnp-3025	1656	4	.	.	PUNCT
fnp-3025	1657	1	131(pt	131(pt	X
fnp-3025	1657	2	12	12	NUM
fnp-3025	1657	3	):	):	PUNCT
fnp-3025	1657	4	p.	p.	NOUN
fnp-3025	1657	5	3299	3299	NUM
fnp-3025	1657	6	-	-	SYM
fnp-3025	1657	7	310	310	NUM
fnp-3025	1657	8	.	.	NOUN
fnp-3025	1657	9	269	269	NUM
fnp-3025	1657	10	.	.	PUNCT
fnp-3025	1658	1	yamada	yamada	PROPN
fnp-3025	1658	2	,	,	PUNCT
fnp-3025	1658	3	m.	m.	NOUN
fnp-3025	1658	4	,	,	PUNCT
fnp-3025	1658	5	cerebral	cerebral	ADJ
fnp-3025	1658	6	amyloid	amyloid	NOUN
fnp-3025	1658	7	angiopathy	angiopathy	NOUN
fnp-3025	1658	8	:	:	PUNCT
fnp-3025	1658	9	emerging	emerge	VERB
fnp-3025	1658	10	concepts	concept	NOUN
fnp-3025	1658	11	.	.	PUNCT
fnp-3025	1659	1	j	j	PROPN
fnp-3025	1659	2	stroke	stroke	PROPN
fnp-3025	1659	3	,	,	PUNCT
fnp-3025	1659	4	2015	2015	NUM
fnp-3025	1659	5	.	.	PUNCT
fnp-3025	1660	1	17(1	17(1	NUM
fnp-3025	1660	2	):	):	PUNCT
fnp-3025	1661	1	p.	p.	NOUN
fnp-3025	1661	2	17	17	NUM
fnp-3025	1661	3	-	-	SYM
fnp-3025	1661	4	30	30	NUM
fnp-3025	1661	5	.	.	PUNCT
fnp-3025	1661	6	270	270	NUM
fnp-3025	1661	7	.	.	PUNCT
fnp-3025	1662	1	probst	probst	PROPN
fnp-3025	1662	2	,	,	PUNCT
fnp-3025	1662	3	a.	a.	NOUN
fnp-3025	1662	4	,	,	PUNCT
fnp-3025	1662	5	et	et	PROPN
fnp-3025	1662	6	al	al	PROPN
fnp-3025	1662	7	.	.	PROPN
fnp-3025	1662	8	,	,	PUNCT
fnp-3025	1662	9	neuritic	neuritic	ADJ
fnp-3025	1662	10	plaques	plaque	NOUN
fnp-3025	1662	11	in	in	ADP
fnp-3025	1662	12	senile	senile	ADJ
fnp-3025	1662	13	dementia	dementia	NOUN
fnp-3025	1662	14	of	of	ADP
fnp-3025	1662	15	alzheimer	alzheimer	PROPN
fnp-3025	1662	16	type	type	NOUN
fnp-3025	1662	17	:	:	PUNCT
fnp-3025	1662	18	a	a	DET
fnp-3025	1662	19	golgi	golgi	NOUN
fnp-3025	1662	20	analysis	analysis	NOUN
fnp-3025	1662	21	in	in	ADP
fnp-3025	1662	22	the	the	DET
fnp-3025	1662	23	hippocampal	hippocampal	ADJ
fnp-3025	1662	24	region	region	NOUN
fnp-3025	1662	25	.	.	PUNCT
fnp-3025	1663	1	brain	brain	NOUN
fnp-3025	1663	2	res	re	NOUN
fnp-3025	1663	3	,	,	PUNCT
fnp-3025	1663	4	1983	1983	NUM
fnp-3025	1663	5	.	.	PUNCT
fnp-3025	1664	1	268(2	268(2	NUM
fnp-3025	1664	2	):	):	PUNCT
fnp-3025	1665	1	p.	p.	NOUN
fnp-3025	1665	2	249	249	NUM
fnp-3025	1665	3	-	-	SYM
fnp-3025	1665	4	54	54	NUM
fnp-3025	1665	5	.	.	PUNCT
fnp-3025	1665	6	271	271	NUM
fnp-3025	1665	7	.	.	X
fnp-3025	1666	1	friedrich	friedrich	PROPN
fnp-3025	1666	2	,	,	PUNCT
fnp-3025	1666	3	r.p	r.p	PROPN
fnp-3025	1666	4	.	.	PROPN
fnp-3025	1666	5	,	,	PUNCT
fnp-3025	1666	6	et	et	PROPN
fnp-3025	1666	7	al	al	PROPN
fnp-3025	1666	8	.	.	PROPN
fnp-3025	1666	9	,	,	PUNCT
fnp-3025	1666	10	mechanism	mechanism	NOUN
fnp-3025	1666	11	of	of	ADP
fnp-3025	1666	12	amyloid	amyloid	NOUN
fnp-3025	1666	13	plaque	plaque	NOUN
fnp-3025	1666	14	formation	formation	NOUN
fnp-3025	1666	15	suggests	suggest	VERB
fnp-3025	1666	16	an	an	DET
fnp-3025	1666	17	intracellular	intracellular	ADJ
fnp-3025	1666	18	basis	basis	NOUN
fnp-3025	1666	19	of	of	ADP
fnp-3025	1666	20	abeta	abeta	PROPN
fnp-3025	1666	21	pathogenicity	pathogenicity	NOUN
fnp-3025	1666	22	.	.	PUNCT
fnp-3025	1667	1	proc	proc	PROPN
fnp-3025	1667	2	natl	natl	PROPN
fnp-3025	1667	3	acad	acad	PROPN
fnp-3025	1667	4	sci	sci	PROPN
fnp-3025	1667	5	u	u	PROPN
fnp-3025	1667	6	s	s	PROPN
fnp-3025	1667	7	a	a	PRON
fnp-3025	1667	8	,	,	PUNCT
fnp-3025	1667	9	2010	2010	NUM
fnp-3025	1667	10	.	.	PUNCT
fnp-3025	1668	1	107(5	107(5	NUM
fnp-3025	1668	2	):	):	PUNCT
fnp-3025	1668	3	p.	p.	NOUN
fnp-3025	1668	4	1942	1942	NUM
fnp-3025	1668	5	-	-	SYM
fnp-3025	1668	6	7	7	NUM
fnp-3025	1668	7	.	.	NUM
fnp-3025	1668	8	272	272	NUM
fnp-3025	1668	9	.	.	PUNCT
fnp-3025	1669	1	takahashi	takahashi	PROPN
fnp-3025	1669	2	,	,	PUNCT
fnp-3025	1669	3	r.h	r.h	PROPN
fnp-3025	1669	4	.	.	PROPN
fnp-3025	1669	5	,	,	PUNCT
fnp-3025	1669	6	t.	t.	PROPN
fnp-3025	1669	7	nagao	nagao	ADJ
fnp-3025	1669	8	,	,	PUNCT
fnp-3025	1669	9	and	and	CCONJ
fnp-3025	1669	10	g.k	g.k	PROPN
fnp-3025	1669	11	.	.	PROPN
fnp-3025	1669	12	gouras	gouras	PROPN
fnp-3025	1669	13	,	,	PUNCT
fnp-3025	1669	14	plaque	plaque	NOUN
fnp-3025	1669	15	formation	formation	NOUN
fnp-3025	1669	16	and	and	CCONJ
fnp-3025	1669	17	the	the	DET
fnp-3025	1669	18	intraneuronal	intraneuronal	ADJ
fnp-3025	1669	19	accumulation	accumulation	NOUN
fnp-3025	1669	20	of	of	ADP
fnp-3025	1669	21	beta	beta	NOUN
fnp-3025	1669	22	-	-	PUNCT
fnp-3025	1669	23	amyloid	amyloid	NOUN
fnp-3025	1669	24	in	in	ADP
fnp-3025	1669	25	alzheimer	alzheimer	PROPN
fnp-3025	1669	26	’s	’s	PART
fnp-3025	1669	27	disease	disease	NOUN
fnp-3025	1669	28	.	.	PUNCT
fnp-3025	1670	1	pathol	pathol	NOUN
fnp-3025	1670	2	int	int	NOUN
fnp-3025	1670	3	,	,	PUNCT
fnp-3025	1670	4	2017	2017	NUM
fnp-3025	1670	5	.	.	PUNCT
fnp-3025	1671	1	67(4	67(4	NUM
fnp-3025	1671	2	):	):	PUNCT
fnp-3025	1672	1	p.	p.	NOUN
fnp-3025	1672	2	185	185	NUM
fnp-3025	1672	3	-	-	SYM
fnp-3025	1672	4	193	193	NUM
fnp-3025	1672	5	.	.	PUNCT
fnp-3025	1672	6	273	273	NUM
fnp-3025	1672	7	.	.	PUNCT
fnp-3025	1673	1	sadleir	sadleir	PROPN
fnp-3025	1673	2	,	,	PUNCT
fnp-3025	1673	3	k.r	k.r	PROPN
fnp-3025	1673	4	.	.	PROPN
fnp-3025	1673	5	,	,	PUNCT
fnp-3025	1673	6	et	et	PROPN
fnp-3025	1673	7	al	al	PROPN
fnp-3025	1673	8	.	.	PROPN
fnp-3025	1673	9	,	,	PUNCT
fnp-3025	1673	10	presynaptic	presynaptic	ADJ
fnp-3025	1673	11	dystrophic	dystrophic	ADJ
fnp-3025	1673	12	neurites	neurite	NOUN
fnp-3025	1673	13	surrounding	surround	VERB
fnp-3025	1673	14	amyloid	amyloid	NOUN
fnp-3025	1673	15	plaques	plaque	NOUN
fnp-3025	1673	16	are	be	AUX
fnp-3025	1673	17	sites	site	NOUN
fnp-3025	1673	18	of	of	ADP
fnp-3025	1673	19	microtubule	microtubule	NOUN
fnp-3025	1673	20	disruption	disruption	NOUN
fnp-3025	1673	21	,	,	PUNCT
fnp-3025	1673	22	bace1	bace1	NOUN
fnp-3025	1673	23	elevation	elevation	NOUN
fnp-3025	1673	24	,	,	PUNCT
fnp-3025	1673	25	and	and	CCONJ
fnp-3025	1673	26	increased	increase	VERB
fnp-3025	1673	27	abeta	abeta	NOUN
fnp-3025	1673	28	generation	generation	NOUN
fnp-3025	1673	29	in	in	ADP
fnp-3025	1673	30	alzheimer	alzheimer	PROPN
fnp-3025	1673	31	’s	’s	PART
fnp-3025	1673	32	disease	disease	NOUN
fnp-3025	1673	33	.	.	PUNCT
fnp-3025	1674	1	acta	acta	PROPN
fnp-3025	1674	2	neuropathol	neuropathol	PROPN
fnp-3025	1674	3	,	,	PUNCT
fnp-3025	1674	4	2016	2016	NUM
fnp-3025	1674	5	.	.	PUNCT
fnp-3025	1675	1	132(2	132(2	NUM
fnp-3025	1675	2	):	):	PUNCT
fnp-3025	1675	3	p.	p.	NOUN
fnp-3025	1675	4	235	235	NUM
fnp-3025	1675	5	-	-	SYM
fnp-3025	1675	6	256	256	NUM
fnp-3025	1675	7	.	.	NOUN
fnp-3025	1675	8	274	274	NUM
fnp-3025	1675	9	.	.	PUNCT
fnp-3025	1676	1	kuchibhotla	kuchibhotla	PROPN
fnp-3025	1676	2	,	,	PUNCT
fnp-3025	1676	3	k.v	k.v	PROPN
fnp-3025	1676	4	.	.	PROPN
fnp-3025	1676	5	,	,	PUNCT
fnp-3025	1676	6	et	et	PROPN
fnp-3025	1676	7	al	al	PROPN
fnp-3025	1676	8	.	.	PROPN
fnp-3025	1676	9	,	,	PUNCT
fnp-3025	1676	10	abeta	abeta	PROPN
fnp-3025	1676	11	plaques	plaque	NOUN
fnp-3025	1676	12	lead	lead	VERB
fnp-3025	1676	13	to	to	ADP
fnp-3025	1676	14	aberrant	aberrant	ADJ
fnp-3025	1676	15	regulation	regulation	NOUN
fnp-3025	1676	16	of	of	ADP
fnp-3025	1676	17	calcium	calcium	NOUN
fnp-3025	1676	18	homeostasis	homeostasis	NOUN
fnp-3025	1676	19	in	in	ADP
fnp-3025	1676	20	vivo	vivo	NOUN
fnp-3025	1676	21	resulting	result	VERB
fnp-3025	1676	22	in	in	ADP
fnp-3025	1676	23	structural	structural	ADJ
fnp-3025	1676	24	and	and	CCONJ
fnp-3025	1676	25	functional	functional	ADJ
fnp-3025	1676	26	disruption	disruption	NOUN
fnp-3025	1676	27	of	of	ADP
fnp-3025	1676	28	neuronal	neuronal	ADJ
fnp-3025	1676	29	networks	network	NOUN
fnp-3025	1676	30	.	.	PUNCT
fnp-3025	1677	1	neuron	neuron	PROPN
fnp-3025	1677	2	,	,	PUNCT
fnp-3025	1677	3	2008	2008	NUM
fnp-3025	1677	4	.	.	PUNCT
fnp-3025	1678	1	59(2	59(2	NUM
fnp-3025	1678	2	):	):	PUNCT
fnp-3025	1678	3	p.	p.	NOUN
fnp-3025	1678	4	214	214	NUM
fnp-3025	1678	5	-	-	SYM
fnp-3025	1678	6	25	25	NUM
fnp-3025	1678	7	.	.	PUNCT
fnp-3025	1679	1	275	275	NUM
fnp-3025	1679	2	.	.	X
fnp-3025	1679	3	sanchez	sanchez	NOUN
fnp-3025	1679	4	-	-	PUNCT
fnp-3025	1679	5	varo	varo	PROPN
fnp-3025	1679	6	,	,	PUNCT
fnp-3025	1679	7	r.	r.	PROPN
fnp-3025	1679	8	,	,	PUNCT
fnp-3025	1679	9	et	et	PROPN
fnp-3025	1679	10	al	al	PROPN
fnp-3025	1679	11	.	.	PROPN
fnp-3025	1679	12	,	,	PUNCT
fnp-3025	1679	13	abnormal	abnormal	ADJ
fnp-3025	1679	14	accumulation	accumulation	NOUN
fnp-3025	1679	15	of	of	ADP
fnp-3025	1679	16	autophagic	autophagic	ADJ
fnp-3025	1679	17	vesicles	vesicle	NOUN
fnp-3025	1679	18	correlates	correlate	VERB
fnp-3025	1679	19	with	with	ADP
fnp-3025	1679	20	axonal	axonal	ADJ
fnp-3025	1679	21	and	and	CCONJ
fnp-3025	1679	22	synaptic	synaptic	ADJ
fnp-3025	1679	23	pathology	pathology	NOUN
fnp-3025	1679	24	in	in	ADP
fnp-3025	1679	25	young	young	ADJ
fnp-3025	1679	26	alzheimer	alzheimer	PROPN
fnp-3025	1679	27	’s	’s	PART
fnp-3025	1679	28	mice	mouse	NOUN
fnp-3025	1679	29	hippocampus	hippocampus	NOUN
fnp-3025	1679	30	.	.	PUNCT
fnp-3025	1680	1	acta	acta	PROPN
fnp-3025	1680	2	neuropathol	neuropathol	PROPN
fnp-3025	1680	3	,	,	PUNCT
fnp-3025	1680	4	2012	2012	NUM
fnp-3025	1680	5	.	.	PUNCT
fnp-3025	1681	1	123(1	123(1	NUM
fnp-3025	1681	2	):	):	PUNCT
fnp-3025	1682	1	p.	p.	NOUN
fnp-3025	1682	2	53	53	NUM
fnp-3025	1682	3	-	-	SYM
fnp-3025	1682	4	70	70	NUM
fnp-3025	1682	5	.	.	PUNCT
fnp-3025	1682	6	276	276	NUM
fnp-3025	1682	7	.	.	PUNCT
fnp-3025	1683	1	wirths	wirth	NOUN
fnp-3025	1683	2	,	,	PUNCT
fnp-3025	1683	3	o.	o.	PROPN
fnp-3025	1683	4	,	,	PUNCT
fnp-3025	1683	5	et	et	PROPN
fnp-3025	1683	6	al	al	PROPN
fnp-3025	1683	7	.	.	PROPN
fnp-3025	1683	8	,	,	PUNCT
fnp-3025	1683	9	lewy	lewy	PROPN
fnp-3025	1683	10	body	body	NOUN
fnp-3025	1683	11	variant	variant	NOUN
fnp-3025	1683	12	of	of	ADP
fnp-3025	1683	13	alzheimer	alzheimer	PROPN
fnp-3025	1683	14	’s	’s	PART
fnp-3025	1683	15	disease	disease	NOUN
fnp-3025	1683	16	:	:	PUNCT
fnp-3025	1683	17	alpha	alpha	NOUN
fnp-3025	1683	18	-	-	PUNCT
fnp-3025	1683	19	synuclein	synuclein	NOUN
fnp-3025	1683	20	in	in	ADP
fnp-3025	1683	21	dystrophic	dystrophic	ADJ
fnp-3025	1683	22	neurites	neurite	NOUN
fnp-3025	1683	23	of	of	ADP
fnp-3025	1683	24	a	a	DET
fnp-3025	1683	25	beta	beta	ADJ
fnp-3025	1683	26	plaques	plaque	NOUN
fnp-3025	1683	27	.	.	PUNCT
fnp-3025	1684	1	neuroreport	neuroreport	NOUN
fnp-3025	1684	2	,	,	PUNCT
fnp-3025	1684	3	2000	2000	NUM
fnp-3025	1684	4	.	.	PUNCT
fnp-3025	1685	1	11(17	11(17	NUM
fnp-3025	1685	2	):	):	PUNCT
fnp-3025	1685	3	p.	p.	NOUN
fnp-3025	1685	4	3737	3737	NUM
fnp-3025	1685	5	-	-	SYM
fnp-3025	1685	6	41	41	NUM
fnp-3025	1685	7	.	.	PUNCT
fnp-3025	1686	1	277	277	NUM
fnp-3025	1686	2	.	.	PUNCT
fnp-3025	1687	1	dickson	dickson	PROPN
fnp-3025	1687	2	,	,	PUNCT
fnp-3025	1687	3	t.c	t.c	PROPN
fnp-3025	1687	4	.	.	PROPN
fnp-3025	1687	5	,	,	PUNCT
fnp-3025	1687	6	et	et	PROPN
fnp-3025	1687	7	al	al	PROPN
fnp-3025	1687	8	.	.	PROPN
fnp-3025	1687	9	,	,	PUNCT
fnp-3025	1687	10	neurochemical	neurochemical	ADJ
fnp-3025	1687	11	diversity	diversity	NOUN
fnp-3025	1687	12	of	of	ADP
fnp-3025	1687	13	dystrophic	dystrophic	ADJ
fnp-3025	1687	14	neurites	neurite	NOUN
fnp-3025	1687	15	in	in	ADP
fnp-3025	1687	16	the	the	DET
fnp-3025	1687	17	early	early	ADJ
fnp-3025	1687	18	and	and	CCONJ
fnp-3025	1687	19	late	late	ADJ
fnp-3025	1687	20	stages	stage	NOUN
fnp-3025	1687	21	of	of	ADP
fnp-3025	1687	22	alzheimer	alzheimer	PROPN
fnp-3025	1687	23	’s	’s	PART
fnp-3025	1687	24	disease	disease	NOUN
fnp-3025	1687	25	.	.	PUNCT
fnp-3025	1688	1	exp	exp	NOUN
fnp-3025	1688	2	neurol	neurol	NOUN
fnp-3025	1688	3	,	,	PUNCT
fnp-3025	1688	4	1999	1999	NUM
fnp-3025	1688	5	.	.	PUNCT
fnp-3025	1689	1	156(1	156(1	NUM
fnp-3025	1689	2	):	):	PUNCT
fnp-3025	1690	1	p.	p.	NOUN
fnp-3025	1690	2	100	100	NUM
fnp-3025	1690	3	-	-	SYM
fnp-3025	1690	4	10	10	NUM
fnp-3025	1690	5	.	.	PUNCT
fnp-3025	1690	6	278	278	NUM
fnp-3025	1690	7	.	.	PUNCT
fnp-3025	1691	1	garcia	garcia	PROPN
fnp-3025	1691	2	-	-	PUNCT
fnp-3025	1691	3	marin	marin	PROPN
fnp-3025	1691	4	,	,	PUNCT
fnp-3025	1691	5	v.	v.	ADV
fnp-3025	1691	6	,	,	PUNCT
fnp-3025	1691	7	p.	p.	NOUN
fnp-3025	1691	8	garcia	garcia	PROPN
fnp-3025	1691	9	-	-	PUNCT
fnp-3025	1691	10	lopez	lopez	NOUN
fnp-3025	1691	11	,	,	PUNCT
fnp-3025	1691	12	and	and	CCONJ
fnp-3025	1691	13	m.	m.	NOUN
fnp-3025	1691	14	freire	freire	PROPN
fnp-3025	1691	15	,	,	PUNCT
fnp-3025	1691	16	cajal	cajal	PROPN
fnp-3025	1691	17	’s	’s	PART
fnp-3025	1691	18	contributions	contribution	NOUN
fnp-3025	1691	19	to	to	ADP
fnp-3025	1691	20	the	the	DET
fnp-3025	1691	21	study	study	NOUN
fnp-3025	1691	22	of	of	ADP
fnp-3025	1691	23	alzheimer	alzheimer	PROPN
fnp-3025	1691	24	’s	’s	PART
fnp-3025	1691	25	disease	disease	NOUN
fnp-3025	1691	26	.	.	PUNCT
fnp-3025	1692	1	j	j	PROPN
fnp-3025	1692	2	alzheimers	alzheimers	PROPN
fnp-3025	1692	3	dis	dis	PROPN
fnp-3025	1692	4	,	,	PUNCT
fnp-3025	1692	5	2007	2007	NUM
fnp-3025	1692	6	.	.	PUNCT
fnp-3025	1693	1	12(2	12(2	NUM
fnp-3025	1693	2	):	):	PUNCT
fnp-3025	1694	1	p.	p.	NOUN
fnp-3025	1694	2	161	161	NUM
fnp-3025	1694	3	-	-	SYM
fnp-3025	1694	4	74	74	NUM
fnp-3025	1694	5	.	.	PUNCT
fnp-3025	1694	6	279	279	NUM
fnp-3025	1694	7	.	.	PUNCT
fnp-3025	1695	1	zhan	zhan	PROPN
fnp-3025	1695	2	,	,	PUNCT
fnp-3025	1695	3	s.s	s.s	PROPN
fnp-3025	1695	4	.	.	PROPN
fnp-3025	1695	5	,	,	PUNCT
fnp-3025	1695	6	et	et	PROPN
fnp-3025	1695	7	al	al	PROPN
fnp-3025	1695	8	.	.	PROPN
fnp-3025	1695	9	,	,	PUNCT
fnp-3025	1695	10	distribution	distribution	NOUN
fnp-3025	1695	11	of	of	ADP
fnp-3025	1695	12	neuronal	neuronal	ADJ
fnp-3025	1695	13	growth	growth	NOUN
fnp-3025	1695	14	-	-	PUNCT
fnp-3025	1695	15	promoting	promote	VERB
fnp-3025	1695	16	factors	factor	NOUN
fnp-3025	1695	17	and	and	CCONJ
fnp-3025	1695	18	cytoskeletal	cytoskeletal	ADJ
fnp-3025	1695	19	proteins	protein	NOUN
fnp-3025	1695	20	in	in	ADP
fnp-3025	1695	21	altered	altered	ADJ
fnp-3025	1695	22	neurites	neurite	NOUN
fnp-3025	1695	23	in	in	ADP
fnp-3025	1695	24	alzheimer	alzheimer	PROPN
fnp-3025	1695	25	’s	’s	PART
fnp-3025	1695	26	disease	disease	NOUN
fnp-3025	1695	27	and	and	CCONJ
fnp-3025	1695	28	non	non	ADJ
fnp-3025	1695	29	-	-	ADJ
fnp-3025	1695	30	demented	demented	ADJ
fnp-3025	1695	31	elderly	elderly	ADJ
fnp-3025	1695	32	.	.	PUNCT
fnp-3025	1696	1	acta	acta	PROPN
fnp-3025	1696	2	neuropathol	neuropathol	PROPN
fnp-3025	1696	3	,	,	PUNCT
fnp-3025	1696	4	1995	1995	NUM
fnp-3025	1696	5	.	.	PUNCT
fnp-3025	1697	1	89(4	89(4	NOUN
fnp-3025	1697	2	):	):	PUNCT
fnp-3025	1697	3	p.	p.	NOUN
fnp-3025	1697	4	356	356	NUM
fnp-3025	1697	5	-	-	SYM
fnp-3025	1697	6	62	62	NUM
fnp-3025	1697	7	.	.	PUNCT
fnp-3025	1698	1	280	280	NUM
fnp-3025	1698	2	.	.	X
fnp-3025	1698	3	phinney	phinney	PROPN
fnp-3025	1698	4	,	,	PUNCT
fnp-3025	1698	5	a.l	a.l	PROPN
fnp-3025	1698	6	.	.	PROPN
fnp-3025	1698	7	,	,	PUNCT
fnp-3025	1698	8	et	et	PROPN
fnp-3025	1698	9	al	al	PROPN
fnp-3025	1698	10	.	.	PROPN
fnp-3025	1698	11	,	,	PUNCT
fnp-3025	1698	12	cerebral	cerebral	ADJ
fnp-3025	1698	13	amyloid	amyloid	NOUN
fnp-3025	1698	14	induces	induce	VERB
fnp-3025	1698	15	aberrant	aberrant	ADJ
fnp-3025	1698	16	axonal	axonal	ADJ
fnp-3025	1698	17	sprouting	sprouting	NOUN
fnp-3025	1698	18	and	and	CCONJ
fnp-3025	1698	19	ectopic	ectopic	NOUN
fnp-3025	1698	20	terminal	terminal	ADJ
fnp-3025	1698	21	formation	formation	NOUN
fnp-3025	1698	22	in	in	ADP
fnp-3025	1698	23	amyloid	amyloid	NOUN
fnp-3025	1698	24	precursor	precursor	NOUN
fnp-3025	1698	25	protein	protein	NOUN
fnp-3025	1698	26	transgenic	transgenic	NOUN
fnp-3025	1698	27	mice	mouse	NOUN
fnp-3025	1698	28	.	.	PUNCT
fnp-3025	1699	1	j	j	PROPN
fnp-3025	1699	2	neurosci	neurosci	PROPN
fnp-3025	1699	3	,	,	PUNCT
fnp-3025	1699	4	1999	1999	NUM
fnp-3025	1699	5	.	.	PUNCT
fnp-3025	1700	1	19(19	19(19	NUM
fnp-3025	1700	2	):	):	PUNCT
fnp-3025	1700	3	p.	p.	NOUN
fnp-3025	1700	4	8552	8552	NUM
fnp-3025	1700	5	-	-	SYM
fnp-3025	1700	6	9	9	NUM
fnp-3025	1700	7	.	.	NUM
fnp-3025	1700	8	281	281	NUM
fnp-3025	1700	9	.	.	PUNCT
fnp-3025	1701	1	chan	chan	NOUN
fnp-3025	1701	2	-	-	PUNCT
fnp-3025	1701	3	palay	palay	NOUN
fnp-3025	1701	4	,	,	PUNCT
fnp-3025	1701	5	v.	v.	ADV
fnp-3025	1701	6	,	,	PUNCT
fnp-3025	1701	7	et	et	PROPN
fnp-3025	1701	8	al	al	PROPN
fnp-3025	1701	9	.	.	PROPN
fnp-3025	1701	10	,	,	PUNCT
fnp-3025	1701	11	distribution	distribution	NOUN
fnp-3025	1701	12	of	of	ADP
fnp-3025	1701	13	altered	alter	VERB
fnp-3025	1701	14	hippocampal	hippocampal	ADJ
fnp-3025	1701	15	neurons	neuron	NOUN
fnp-3025	1701	16	and	and	CCONJ
fnp-3025	1701	17	axons	axon	NOUN
fnp-3025	1701	18	immunoreactive	immunoreactive	ADJ
fnp-3025	1701	19	with	with	ADP
fnp-3025	1701	20	antisera	antisera	NOUN
fnp-3025	1701	21	against	against	ADP
fnp-3025	1701	22	neuropeptide	neuropeptide	NOUN
fnp-3025	1701	23	y	y	PROPN
fnp-3025	1701	24	in	in	ADP
fnp-3025	1701	25	alzheimer’s	alzheimer’s	ADJ
fnp-3025	1701	26	-	-	PUNCT
fnp-3025	1701	27	type	type	NOUN
fnp-3025	1701	28	dementia	dementia	NOUN
fnp-3025	1701	29	.	.	PUNCT
fnp-3025	1702	1	j	j	PROPN
fnp-3025	1702	2	comp	comp	PROPN
fnp-3025	1702	3	neurol	neurol	PROPN
fnp-3025	1702	4	,	,	PUNCT
fnp-3025	1702	5	1986	1986	NUM
fnp-3025	1702	6	.	.	PUNCT
fnp-3025	1703	1	248(3	248(3	NUM
fnp-3025	1703	2	):	):	PUNCT
fnp-3025	1703	3	p.	p.	NOUN
fnp-3025	1703	4	376	376	NUM
fnp-3025	1703	5	-	-	SYM
fnp-3025	1703	6	94	94	NUM
fnp-3025	1703	7	.	.	PUNCT
fnp-3025	1703	8	282	282	NUM
fnp-3025	1703	9	.	.	PUNCT
fnp-3025	1704	1	kitt	kitt	PROPN
fnp-3025	1704	2	,	,	PUNCT
fnp-3025	1704	3	c.a	c.a	PROPN
fnp-3025	1704	4	.	.	PROPN
fnp-3025	1704	5	,	,	PUNCT
fnp-3025	1704	6	et	et	PROPN
fnp-3025	1704	7	al	al	PROPN
fnp-3025	1704	8	.	.	PROPN
fnp-3025	1704	9	,	,	PUNCT
fnp-3025	1704	10	evidence	evidence	NOUN
fnp-3025	1704	11	for	for	ADP
fnp-3025	1704	12	cholinergic	cholinergic	ADJ
fnp-3025	1704	13	neurites	neurite	NOUN
fnp-3025	1704	14	in	in	ADP
fnp-3025	1704	15	senile	senile	ADJ
fnp-3025	1704	16	plaques	plaque	NOUN
fnp-3025	1704	17	.	.	PUNCT
fnp-3025	1705	1	science	science	NOUN
fnp-3025	1705	2	,	,	PUNCT
fnp-3025	1705	3	1984	1984	NUM
fnp-3025	1705	4	.	.	PUNCT
fnp-3025	1706	1	226(4681	226(4681	NUM
fnp-3025	1706	2	):	):	PUNCT
fnp-3025	1706	3	p.	p.	NOUN
fnp-3025	1706	4	1443	1443	NUM
fnp-3025	1706	5	-	-	SYM
fnp-3025	1706	6	5	5	NUM
fnp-3025	1706	7	.	.	NOUN
fnp-3025	1706	8	283	283	NUM
fnp-3025	1706	9	.	.	PUNCT
fnp-3025	1707	1	kitt	kitt	PROPN
fnp-3025	1707	2	,	,	PUNCT
fnp-3025	1707	3	c.a	c.a	PROPN
fnp-3025	1707	4	.	.	PROPN
fnp-3025	1707	5	,	,	PUNCT
fnp-3025	1707	6	et	et	PROPN
fnp-3025	1707	7	al	al	PROPN
fnp-3025	1707	8	.	.	PROPN
fnp-3025	1707	9	,	,	PUNCT
fnp-3025	1707	10	catecholaminergic	catecholaminergic	ADJ
fnp-3025	1707	11	neurites	neurite	NOUN
fnp-3025	1707	12	in	in	ADP
fnp-3025	1707	13	senile	senile	ADJ
fnp-3025	1707	14	plaques	plaque	NOUN
fnp-3025	1707	15	in	in	ADP
fnp-3025	1707	16	prefrontal	prefrontal	ADJ
fnp-3025	1707	17	cortex	cortex	NOUN
fnp-3025	1707	18	of	of	ADP
fnp-3025	1707	19	aged	aged	ADJ
fnp-3025	1707	20	nonhuman	nonhuman	ADJ
fnp-3025	1707	21	primates	primate	NOUN
fnp-3025	1707	22	.	.	PUNCT
fnp-3025	1708	1	neuroscience	neuroscience	NOUN
fnp-3025	1708	2	,	,	PUNCT
fnp-3025	1708	3	1985	1985	NUM
fnp-3025	1708	4	.	.	PUNCT
fnp-3025	1709	1	16(3	16(3	NUM
fnp-3025	1709	2	):	):	PUNCT
fnp-3025	1709	3	p.	p.	NOUN
fnp-3025	1709	4	691	691	NUM
fnp-3025	1709	5	-	-	SYM
fnp-3025	1709	6	9	9	NUM
fnp-3025	1709	7	.	.	NUM
fnp-3025	1709	8	284	284	NUM
fnp-3025	1709	9	.	.	PUNCT
fnp-3025	1710	1	kitt	kitt	PROPN
fnp-3025	1710	2	,	,	PUNCT
fnp-3025	1710	3	c.a	c.a	PROPN
fnp-3025	1710	4	.	.	PROPN
fnp-3025	1710	5	,	,	PUNCT
fnp-3025	1710	6	et	et	PROPN
fnp-3025	1710	7	al	al	PROPN
fnp-3025	1710	8	.	.	PROPN
fnp-3025	1710	9	,	,	PUNCT
fnp-3025	1710	10	serotoninergic	serotoninergic	ADJ
fnp-3025	1710	11	neurites	neurite	NOUN
fnp-3025	1710	12	in	in	ADP
fnp-3025	1710	13	senile	senile	ADJ
fnp-3025	1710	14	plaques	plaque	NOUN
fnp-3025	1710	15	in	in	ADP
fnp-3025	1710	16	cingulate	cingulate	ADJ
fnp-3025	1710	17	cortex	cortex	NOUN
fnp-3025	1710	18	of	of	ADP
fnp-3025	1710	19	aged	aged	ADJ
fnp-3025	1710	20	nonhuman	nonhuman	ADJ
fnp-3025	1710	21	primate	primate	NOUN
fnp-3025	1710	22	.	.	PUNCT
fnp-3025	1711	1	synapse	synapse	NOUN
fnp-3025	1711	2	,	,	PUNCT
fnp-3025	1711	3	1989	1989	NUM
fnp-3025	1711	4	.	.	PUNCT
fnp-3025	1712	1	3(1	3(1	NUM
fnp-3025	1712	2	):	):	PUNCT
fnp-3025	1713	1	p.	p.	NOUN
fnp-3025	1713	2	12	12	NUM
fnp-3025	1713	3	-	-	SYM
fnp-3025	1713	4	8	8	NUM
fnp-3025	1713	5	.	.	NOUN
fnp-3025	1713	6	285	285	NUM
fnp-3025	1713	7	.	.	PUNCT
fnp-3025	1714	1	morrison	morrison	PROPN
fnp-3025	1714	2	,	,	PUNCT
fnp-3025	1714	3	j.h	j.h	PROPN
fnp-3025	1714	4	.	.	PROPN
fnp-3025	1714	5	,	,	PUNCT
fnp-3025	1714	6	et	et	PROPN
fnp-3025	1714	7	al	al	PROPN
fnp-3025	1714	8	.	.	PROPN
fnp-3025	1714	9	,	,	PUNCT
fnp-3025	1714	10	somatostatin	somatostatin	NOUN
fnp-3025	1714	11	immunoreactivity	immunoreactivity	NOUN
fnp-3025	1714	12	in	in	ADP
fnp-3025	1714	13	neuritic	neuritic	ADJ
fnp-3025	1714	14	plaques	plaque	NOUN
fnp-3025	1714	15	of	of	ADP
fnp-3025	1714	16	alzheimer	alzheimer	PROPN
fnp-3025	1714	17	’s	’s	PART
fnp-3025	1714	18	patients	patient	NOUN
fnp-3025	1714	19	.	.	PUNCT
fnp-3025	1715	1	nature	nature	NOUN
fnp-3025	1715	2	,	,	PUNCT
fnp-3025	1715	3	1985	1985	NUM
fnp-3025	1715	4	.	.	PUNCT
fnp-3025	1716	1	314(6006	314(6006	NUM
fnp-3025	1716	2	):	):	PUNCT
fnp-3025	1716	3	p.	p.	NOUN
fnp-3025	1716	4	90	90	NUM
fnp-3025	1716	5	-	-	SYM
fnp-3025	1716	6	2	2	NUM
fnp-3025	1716	7	.	.	NOUN
fnp-3025	1716	8	286	286	NUM
fnp-3025	1716	9	.	.	PUNCT
fnp-3025	1717	1	struble	struble	ADJ
fnp-3025	1717	2	,	,	PUNCT
fnp-3025	1717	3	r.g	r.g	PROPN
fnp-3025	1717	4	.	.	PROPN
fnp-3025	1717	5	,	,	PUNCT
fnp-3025	1717	6	et	et	PROPN
fnp-3025	1717	7	al	al	PROPN
fnp-3025	1717	8	.	.	PROPN
fnp-3025	1717	9	,	,	PUNCT
fnp-3025	1717	10	neuropeptidergic	neuropeptidergic	ADJ
fnp-3025	1717	11	systems	system	NOUN
fnp-3025	1717	12	in	in	ADP
fnp-3025	1717	13	plaques	plaque	NOUN
fnp-3025	1717	14	of	of	ADP
fnp-3025	1717	15	alzheimer	alzheimer	PROPN
fnp-3025	1717	16	’s	’s	PART
fnp-3025	1717	17	disease	disease	NOUN
fnp-3025	1717	18	.	.	PUNCT
fnp-3025	1718	1	j	j	PROPN
fnp-3025	1718	2	neuropathol	neuropathol	PROPN
fnp-3025	1718	3	exp	exp	PROPN
fnp-3025	1718	4	neurol	neurol	PROPN
fnp-3025	1718	5	,	,	PUNCT
fnp-3025	1718	6	1987	1987	NUM
fnp-3025	1718	7	.	.	PUNCT
fnp-3025	1719	1	46(5	46(5	NOUN
fnp-3025	1719	2	):	):	PUNCT
fnp-3025	1720	1	p.	p.	NOUN
fnp-3025	1720	2	567	567	NUM
fnp-3025	1720	3	-	-	SYM
fnp-3025	1720	4	84	84	NUM
fnp-3025	1720	5	.	.	PUNCT
fnp-3025	1721	1	287	287	NUM
fnp-3025	1721	2	.	.	X
fnp-3025	1721	3	walker	walker	PROPN
fnp-3025	1721	4	,	,	PUNCT
fnp-3025	1721	5	l.c	l.c	PROPN
fnp-3025	1721	6	.	.	PROPN
fnp-3025	1721	7	,	,	PUNCT
fnp-3025	1721	8	et	et	PROPN
fnp-3025	1721	9	al	al	PROPN
fnp-3025	1721	10	.	.	PROPN
fnp-3025	1721	11	,	,	PUNCT
fnp-3025	1721	12	glutamic	glutamic	ADJ
fnp-3025	1721	13	acid	acid	NOUN
fnp-3025	1721	14	decarboxylase	decarboxylase	NOUN
fnp-3025	1721	15	-	-	PUNCT
fnp-3025	1721	16	like	like	ADJ
fnp-3025	1721	17	immunoreactive	immunoreactive	ADJ
fnp-3025	1721	18	neurites	neurite	NOUN
fnp-3025	1721	19	in	in	ADP
fnp-3025	1721	20	senile	senile	ADJ
fnp-3025	1721	21	plaques	plaque	NOUN
fnp-3025	1721	22	.	.	PUNCT
fnp-3025	1722	1	neurosci	neurosci	PROPN
fnp-3025	1722	2	lett	lett	PROPN
fnp-3025	1722	3	,	,	PUNCT
fnp-3025	1722	4	1985	1985	NUM
fnp-3025	1722	5	.	.	PUNCT
fnp-3025	1723	1	59(2	59(2	NUM
fnp-3025	1723	2	):	):	PUNCT
fnp-3025	1723	3	p.	p.	NOUN
fnp-3025	1723	4	165	165	NUM
fnp-3025	1723	5	-	-	SYM
fnp-3025	1723	6	9	9	NUM
fnp-3025	1723	7	.	.	X
fnp-3025	1724	1	288	288	NUM
fnp-3025	1724	2	.	.	PUNCT
fnp-3025	1725	1	armstrong	armstrong	PROPN
fnp-3025	1725	2	,	,	PUNCT
fnp-3025	1725	3	d.m	d.m	PROPN
fnp-3025	1725	4	.	.	PROPN
fnp-3025	1725	5	,	,	PUNCT
fnp-3025	1725	6	et	et	PROPN
fnp-3025	1725	7	al	al	PROPN
fnp-3025	1725	8	.	.	PROPN
fnp-3025	1725	9	,	,	PUNCT
fnp-3025	1725	10	substance	substance	NOUN
fnp-3025	1725	11	p	p	NOUN
fnp-3025	1725	12	and	and	CCONJ
fnp-3025	1725	13	somatostatin	somatostatin	NOUN
fnp-3025	1725	14	coexist	coexist	VERB
fnp-3025	1725	15	within	within	ADP
fnp-3025	1725	16	neuritic	neuritic	ADJ
fnp-3025	1725	17	plaques	plaque	NOUN
fnp-3025	1725	18	:	:	PUNCT
fnp-3025	1725	19	implications	implication	NOUN
fnp-3025	1725	20	for	for	ADP
fnp-3025	1725	21	the	the	DET
fnp-3025	1725	22	pathogenesis	pathogenesis	NOUN
fnp-3025	1725	23	of	of	ADP
fnp-3025	1725	24	alzheimer	alzheimer	PROPN
fnp-3025	1725	25	’s	’s	PART
fnp-3025	1725	26	disease	disease	NOUN
fnp-3025	1725	27	.	.	PUNCT
fnp-3025	1726	1	neuroscience	neuroscience	NOUN
fnp-3025	1726	2	,	,	PUNCT
fnp-3025	1726	3	1989	1989	NUM
fnp-3025	1726	4	.	.	PUNCT
fnp-3025	1727	1	31(3	31(3	NUM
fnp-3025	1727	2	):	):	PUNCT
fnp-3025	1728	1	p.	p.	NOUN
fnp-3025	1728	2	663	663	NUM
fnp-3025	1728	3	-	-	SYM
fnp-3025	1728	4	71	71	NUM
fnp-3025	1728	5	.	.	PUNCT
fnp-3025	1728	6	289	289	NUM
fnp-3025	1728	7	.	.	PUNCT
fnp-3025	1728	8	walker	walker	PROPN
fnp-3025	1728	9	,	,	PUNCT
fnp-3025	1728	10	l.c	l.c	PROPN
fnp-3025	1728	11	.	.	PROPN
fnp-3025	1728	12	,	,	PUNCT
fnp-3025	1728	13	et	et	PROPN
fnp-3025	1728	14	al	al	PROPN
fnp-3025	1728	15	.	.	PROPN
fnp-3025	1728	16	,	,	PUNCT
fnp-3025	1728	17	multiple	multiple	ADJ
fnp-3025	1728	18	transmitter	transmitter	NOUN
fnp-3025	1728	19	systems	system	NOUN
fnp-3025	1728	20	contribute	contribute	VERB
fnp-3025	1728	21	neurites	neurite	NOUN
fnp-3025	1728	22	to	to	ADP
fnp-3025	1728	23	individual	individual	ADJ
fnp-3025	1728	24	senile	senile	ADJ
fnp-3025	1728	25	plaques	plaque	NOUN
fnp-3025	1728	26	.	.	PUNCT
fnp-3025	1729	1	j	j	PROPN
fnp-3025	1729	2	neuropathol	neuropathol	PROPN
fnp-3025	1729	3	exp	exp	PROPN
fnp-3025	1729	4	neurol	neurol	PROPN
fnp-3025	1729	5	,	,	PUNCT
fnp-3025	1729	6	1988	1988	NUM
fnp-3025	1729	7	.	.	PUNCT
fnp-3025	1730	1	47(2	47(2	PROPN
fnp-3025	1730	2	):	):	PUNCT
fnp-3025	1731	1	p.	p.	NOUN
fnp-3025	1731	2	138	138	NUM
fnp-3025	1731	3	-	-	SYM
fnp-3025	1731	4	44	44	NUM
fnp-3025	1731	5	.	.	PUNCT
fnp-3025	1731	6	290	290	NUM
fnp-3025	1731	7	.	.	PUNCT
fnp-3025	1732	1	price	price	NOUN
fnp-3025	1732	2	,	,	PUNCT
fnp-3025	1732	3	d.l	d.l	PROPN
fnp-3025	1732	4	.	.	PROPN
fnp-3025	1732	5	,	,	PUNCT
fnp-3025	1732	6	et	et	PROPN
fnp-3025	1732	7	al	al	PROPN
fnp-3025	1732	8	.	.	PROPN
fnp-3025	1732	9	,	,	PUNCT
fnp-3025	1732	10	basal	basal	VERB
fnp-3025	1732	11	forebrain	forebrain	NOUN
fnp-3025	1732	12	cholinergic	cholinergic	ADJ
fnp-3025	1732	13	systems	system	NOUN
fnp-3025	1732	14	in	in	ADP
fnp-3025	1732	15	alzheimer	alzheimer	PROPN
fnp-3025	1732	16	’s	’s	PART
fnp-3025	1732	17	disease	disease	NOUN
fnp-3025	1732	18	and	and	CCONJ
fnp-3025	1732	19	related	related	ADJ
fnp-3025	1732	20	dementias	dementia	NOUN
fnp-3025	1732	21	.	.	PUNCT
fnp-3025	1733	1	neuroscience	neuroscience	NOUN
fnp-3025	1733	2	commentaries	commentary	NOUN
fnp-3025	1733	3	,	,	PUNCT
fnp-3025	1733	4	1982	1982	NUM
fnp-3025	1733	5	.	.	PUNCT
fnp-3025	1734	1	1	1	NUM
fnp-3025	1734	2	:	:	PUNCT
fnp-3025	1734	3	p.	p.	NOUN
fnp-3025	1734	4	84	84	NUM
fnp-3025	1734	5	-	-	SYM
fnp-3025	1734	6	92	92	NUM
fnp-3025	1734	7	.	.	X
fnp-3025	1734	8	291	291	NUM
fnp-3025	1734	9	.	.	PUNCT
fnp-3025	1735	1	benzing	benze	VERB
fnp-3025	1735	2	,	,	PUNCT
fnp-3025	1735	3	w.c	w.c	PROPN
fnp-3025	1735	4	.	.	PROPN
fnp-3025	1735	5	,	,	PUNCT
fnp-3025	1735	6	e.j	e.j	PROPN
fnp-3025	1735	7	.	.	PROPN
fnp-3025	1735	8	mufson	mufson	PROPN
fnp-3025	1735	9	,	,	PUNCT
fnp-3025	1735	10	and	and	CCONJ
fnp-3025	1735	11	d.m	d.m	PROPN
fnp-3025	1735	12	.	.	PUNCT
fnp-3025	1736	1	armstrong	armstrong	PROPN
fnp-3025	1736	2	,	,	PUNCT
fnp-3025	1736	3	alzheimer	alzheimer	PROPN
fnp-3025	1736	4	’s	’s	PART
fnp-3025	1736	5	disease	disease	NOUN
fnp-3025	1736	6	-	-	PUNCT
fnp-3025	1736	7	like	like	ADJ
fnp-3025	1736	8	dystrophic	dystrophic	ADJ
fnp-3025	1736	9	neurites	neurite	NOUN
fnp-3025	1736	10	characteristically	characteristically	ADV
fnp-3025	1736	11	associated	associate	VERB
fnp-3025	1736	12	with	with	ADP
fnp-3025	1736	13	senile	senile	ADJ
fnp-3025	1736	14	plaques	plaque	NOUN
fnp-3025	1736	15	are	be	AUX
fnp-3025	1736	16	not	not	PART
fnp-3025	1736	17	found	find	VERB
fnp-3025	1736	18	within	within	ADP
fnp-3025	1736	19	other	other	ADJ
fnp-3025	1736	20	neurodegenerative	neurodegenerative	ADJ
fnp-3025	1736	21	diseases	disease	NOUN
fnp-3025	1736	22	unless	unless	SCONJ
fnp-3025	1736	23	amyloid	amyloid	NOUN
fnp-3025	1736	24	beta	beta	NOUN
fnp-3025	1736	25	-	-	PUNCT
fnp-3025	1736	26	protein	protein	NOUN
fnp-3025	1736	27	deposition	deposition	NOUN
fnp-3025	1736	28	is	be	AUX
fnp-3025	1736	29	present	present	ADJ
fnp-3025	1736	30	.	.	PUNCT
fnp-3025	1737	1	brain	brain	NOUN
fnp-3025	1737	2	res	re	NOUN
fnp-3025	1737	3	,	,	PUNCT
fnp-3025	1737	4	1993	1993	NUM
fnp-3025	1737	5	.	.	PUNCT
fnp-3025	1738	1	606(1	606(1	NUM
fnp-3025	1738	2	):	):	PUNCT
fnp-3025	1738	3	p.	p.	NOUN
fnp-3025	1738	4	10	10	NUM
fnp-3025	1738	5	-	-	SYM
fnp-3025	1738	6	8	8	NUM
fnp-3025	1738	7	.	.	PUNCT
fnp-3025	1739	1	292	292	NUM
fnp-3025	1739	2	.	.	PUNCT
fnp-3025	1740	1	dekosky	dekosky	PROPN
fnp-3025	1740	2	,	,	PUNCT
fnp-3025	1740	3	s.t	s.t	PROPN
fnp-3025	1740	4	.	.	PROPN
fnp-3025	1740	5	and	and	CCONJ
fnp-3025	1740	6	s.w	s.w	PROPN
fnp-3025	1740	7	.	.	PROPN
fnp-3025	1740	8	scheff	scheff	PROPN
fnp-3025	1740	9	,	,	PUNCT
fnp-3025	1740	10	synapse	synapse	VERB
fnp-3025	1740	11	loss	loss	NOUN
fnp-3025	1740	12	in	in	ADP
fnp-3025	1740	13	frontal	frontal	ADJ
fnp-3025	1740	14	cortex	cortex	NOUN
fnp-3025	1740	15	biopsies	biopsy	NOUN
fnp-3025	1740	16	in	in	ADP
fnp-3025	1740	17	alzheimer	alzheimer	PROPN
fnp-3025	1740	18	’s	’s	PART
fnp-3025	1740	19	disease	disease	NOUN
fnp-3025	1740	20	:	:	PUNCT
fnp-3025	1740	21	correlation	correlation	NOUN
fnp-3025	1740	22	with	with	ADP
fnp-3025	1740	23	cognitive	cognitive	ADJ
fnp-3025	1740	24	severity	severity	NOUN
fnp-3025	1740	25	.	.	PUNCT
fnp-3025	1741	1	ann	ann	PROPN
fnp-3025	1741	2	neurol	neurol	PROPN
fnp-3025	1741	3	,	,	PUNCT
fnp-3025	1741	4	1990	1990	NUM
fnp-3025	1741	5	.	.	PUNCT
fnp-3025	1742	1	27(5	27(5	NOUN
fnp-3025	1742	2	):	):	PUNCT
fnp-3025	1743	1	p.	p.	NOUN
fnp-3025	1743	2	457	457	NUM
fnp-3025	1743	3	-	-	SYM
fnp-3025	1743	4	64	64	NUM
fnp-3025	1743	5	.	.	PUNCT
fnp-3025	1743	6	293	293	NUM
fnp-3025	1743	7	.	.	PUNCT
fnp-3025	1744	1	dekosky	dekosky	PROPN
fnp-3025	1744	2	,	,	PUNCT
fnp-3025	1744	3	s.t	s.t	PROPN
fnp-3025	1744	4	.	.	PROPN
fnp-3025	1744	5	,	,	PUNCT
fnp-3025	1744	6	s.w	s.w	PROPN
fnp-3025	1744	7	.	.	PROPN
fnp-3025	1744	8	scheff	scheff	PROPN
fnp-3025	1744	9	,	,	PUNCT
fnp-3025	1744	10	and	and	CCONJ
fnp-3025	1744	11	s.d	s.d	PROPN
fnp-3025	1744	12	.	.	PROPN
fnp-3025	1744	13	styren	styren	PROPN
fnp-3025	1744	14	,	,	PUNCT
fnp-3025	1744	15	structural	structural	ADJ
fnp-3025	1744	16	correlates	correlate	NOUN
fnp-3025	1744	17	of	of	ADP
fnp-3025	1744	18	cognition	cognition	NOUN
fnp-3025	1744	19	in	in	ADP
fnp-3025	1744	20	dementia	dementia	NOUN
fnp-3025	1744	21	:	:	PUNCT
fnp-3025	1744	22	quantification	quantification	NOUN
fnp-3025	1744	23	and	and	CCONJ
fnp-3025	1744	24	assessment	assessment	NOUN
fnp-3025	1744	25	of	of	ADP
fnp-3025	1744	26	synapse	synapse	NOUN
fnp-3025	1744	27	change	change	NOUN
fnp-3025	1744	28	.	.	PUNCT
fnp-3025	1745	1	neurodegeneration	neurodegeneration	NOUN
fnp-3025	1745	2	,	,	PUNCT
fnp-3025	1745	3	1996	1996	NUM
fnp-3025	1745	4	.	.	PUNCT
fnp-3025	1746	1	5(4	5(4	NUM
fnp-3025	1746	2	):	):	PUNCT
fnp-3025	1747	1	p.	p.	NOUN
fnp-3025	1747	2	417	417	NUM
fnp-3025	1747	3	-	-	SYM
fnp-3025	1747	4	21	21	NUM
fnp-3025	1747	5	.	.	PUNCT
fnp-3025	1747	6	294	294	NUM
fnp-3025	1747	7	.	.	PUNCT
fnp-3025	1748	1	masliah	masliah	PROPN
fnp-3025	1748	2	,	,	PUNCT
fnp-3025	1748	3	e.	e.	PROPN
fnp-3025	1748	4	,	,	PUNCT
fnp-3025	1748	5	et	et	PROPN
fnp-3025	1748	6	al	al	PROPN
fnp-3025	1748	7	.	.	PROPN
fnp-3025	1748	8	,	,	PUNCT
fnp-3025	1748	9	synaptic	synaptic	ADJ
fnp-3025	1748	10	and	and	CCONJ
fnp-3025	1748	11	neuritic	neuritic	ADJ
fnp-3025	1748	12	alterations	alteration	NOUN
fnp-3025	1748	13	during	during	ADP
fnp-3025	1748	14	the	the	DET
fnp-3025	1748	15	progression	progression	NOUN
fnp-3025	1748	16	of	of	ADP
fnp-3025	1748	17	alzheimer	alzheimer	PROPN
fnp-3025	1748	18	’s	’s	PART
fnp-3025	1748	19	disease	disease	NOUN
fnp-3025	1748	20	.	.	PUNCT
fnp-3025	1749	1	neurosci	neurosci	PROPN
fnp-3025	1749	2	lett	lett	PROPN
fnp-3025	1749	3	,	,	PUNCT
fnp-3025	1749	4	1994	1994	NUM
fnp-3025	1749	5	.	.	PUNCT
fnp-3025	1750	1	174(1	174(1	NUM
fnp-3025	1750	2	):	):	PUNCT
fnp-3025	1750	3	p.	p.	NOUN
fnp-3025	1750	4	67	67	NUM
fnp-3025	1750	5	-	-	SYM
fnp-3025	1750	6	72	72	NUM
fnp-3025	1750	7	.	.	NOUN
fnp-3025	1750	8	295	295	NUM
fnp-3025	1750	9	.	.	PUNCT
fnp-3025	1751	1	terry	terry	PROPN
fnp-3025	1751	2	,	,	PUNCT
fnp-3025	1751	3	r.d	r.d	PROPN
fnp-3025	1751	4	.	.	PROPN
fnp-3025	1751	5	,	,	PUNCT
fnp-3025	1751	6	et	et	PROPN
fnp-3025	1751	7	al	al	PROPN
fnp-3025	1751	8	.	.	PROPN
fnp-3025	1751	9	,	,	PUNCT
fnp-3025	1751	10	physical	physical	ADJ
fnp-3025	1751	11	basis	basis	NOUN
fnp-3025	1751	12	of	of	ADP
fnp-3025	1751	13	cognitive	cognitive	ADJ
fnp-3025	1751	14	alterations	alteration	NOUN
fnp-3025	1751	15	in	in	ADP
fnp-3025	1751	16	alzheimer	alzheimer	PROPN
fnp-3025	1751	17	’s	’s	PART
fnp-3025	1751	18	disease	disease	NOUN
fnp-3025	1751	19	:	:	PUNCT
fnp-3025	1751	20	synapse	synapse	NOUN
fnp-3025	1751	21	loss	loss	NOUN
fnp-3025	1751	22	is	be	AUX
fnp-3025	1751	23	the	the	DET
fnp-3025	1751	24	major	major	ADJ
fnp-3025	1751	25	correlate	correlate	NOUN
fnp-3025	1751	26	of	of	ADP
fnp-3025	1751	27	cognitive	cognitive	ADJ
fnp-3025	1751	28	impairment	impairment	NOUN
fnp-3025	1751	29	.	.	PUNCT
fnp-3025	1752	1	ann	ann	PROPN
fnp-3025	1752	2	neurol	neurol	PROPN
fnp-3025	1752	3	,	,	PUNCT
fnp-3025	1752	4	1991	1991	NUM
fnp-3025	1752	5	.	.	PUNCT
fnp-3025	1753	1	30(4	30(4	NUM
fnp-3025	1753	2	):	):	PUNCT
fnp-3025	1753	3	p.	p.	NOUN
fnp-3025	1753	4	572	572	NUM
fnp-3025	1753	5	-	-	SYM
fnp-3025	1753	6	80	80	NUM
fnp-3025	1753	7	.	.	PUNCT
fnp-3025	1754	1	296	296	NUM
fnp-3025	1754	2	.	.	PUNCT
fnp-3025	1755	1	koffie	koffie	PROPN
fnp-3025	1755	2	,	,	PUNCT
fnp-3025	1755	3	r.m	r.m	PROPN
fnp-3025	1755	4	.	.	PROPN
fnp-3025	1755	5	,	,	PUNCT
fnp-3025	1755	6	b.t	b.t	PROPN
fnp-3025	1755	7	.	.	PROPN
fnp-3025	1755	8	hyman	hyman	PROPN
fnp-3025	1755	9	,	,	PUNCT
fnp-3025	1755	10	and	and	CCONJ
fnp-3025	1755	11	t.l	t.l	PROPN
fnp-3025	1755	12	.	.	PUNCT
fnp-3025	1756	1	spires	spires	PROPN
fnp-3025	1756	2	-	-	PUNCT
fnp-3025	1756	3	jones	jones	PROPN
fnp-3025	1756	4	,	,	PUNCT
fnp-3025	1756	5	alzheimer	alzheimer	PROPN
fnp-3025	1756	6	’s	’s	PART
fnp-3025	1756	7	disease	disease	NOUN
fnp-3025	1756	8	:	:	PUNCT
fnp-3025	1756	9	synapses	synapses	AUX
fnp-3025	1756	10	gone	go	VERB
fnp-3025	1756	11	cold	cold	ADJ
fnp-3025	1756	12	.	.	PUNCT
fnp-3025	1757	1	mol	mol	ADP
fnp-3025	1757	2	neurodegener	neurodegener	NOUN
fnp-3025	1757	3	,	,	PUNCT
fnp-3025	1757	4	2011	2011	NUM
fnp-3025	1757	5	.	.	PUNCT
fnp-3025	1758	1	6(1	6(1	NUM
fnp-3025	1758	2	):	):	PUNCT
fnp-3025	1759	1	p.	p.	NOUN
fnp-3025	1759	2	63	63	NUM
fnp-3025	1759	3	.	.	PUNCT
fnp-3025	1759	4	297	297	NUM
fnp-3025	1759	5	.	.	PUNCT
fnp-3025	1760	1	spires	spire	NOUN
fnp-3025	1760	2	-	-	PUNCT
fnp-3025	1760	3	jones	jones	PROPN
fnp-3025	1760	4	,	,	PUNCT
fnp-3025	1760	5	t.l	t.l	PROPN
fnp-3025	1760	6	.	.	PROPN
fnp-3025	1760	7	and	and	CCONJ
fnp-3025	1760	8	b.t	b.t	PROPN
fnp-3025	1760	9	.	.	PROPN
fnp-3025	1760	10	hyman	hyman	PROPN
fnp-3025	1760	11	,	,	PUNCT
fnp-3025	1760	12	the	the	DET
fnp-3025	1760	13	intersection	intersection	NOUN
fnp-3025	1760	14	of	of	ADP
fnp-3025	1760	15	amyloid	amyloid	NOUN
fnp-3025	1760	16	beta	beta	NOUN
fnp-3025	1760	17	and	and	CCONJ
fnp-3025	1760	18	tau	tau	PROPN
fnp-3025	1760	19	at	at	ADP
fnp-3025	1760	20	synapses	synapsis	NOUN
fnp-3025	1760	21	in	in	ADP
fnp-3025	1760	22	alzheimer	alzheimer	PROPN
fnp-3025	1760	23	’s	’s	PART
fnp-3025	1760	24	disease	disease	NOUN
fnp-3025	1760	25	.	.	PUNCT
fnp-3025	1760	26	neuron	neuron	PROPN
fnp-3025	1760	27	,	,	PUNCT
fnp-3025	1760	28	2014	2014	NUM
fnp-3025	1760	29	.	.	PUNCT
fnp-3025	1761	1	82(4	82(4	NUM
fnp-3025	1761	2	):	):	PUNCT
fnp-3025	1762	1	p.	p.	NOUN
fnp-3025	1762	2	756	756	NUM
fnp-3025	1762	3	-	-	SYM
fnp-3025	1762	4	71	71	NUM
fnp-3025	1762	5	.	.	PUNCT
fnp-3025	1762	6	298	298	NUM
fnp-3025	1762	7	.	.	PUNCT
fnp-3025	1763	1	sims	sim	NOUN
fnp-3025	1763	2	,	,	PUNCT
fnp-3025	1763	3	r.	r.	PROPN
fnp-3025	1763	4	,	,	PUNCT
fnp-3025	1763	5	m.	m.	PROPN
fnp-3025	1763	6	hill	hill	PROPN
fnp-3025	1763	7	,	,	PUNCT
fnp-3025	1763	8	and	and	CCONJ
fnp-3025	1763	9	j.	j.	PROPN
fnp-3025	1763	10	williams	williams	PROPN
fnp-3025	1763	11	,	,	PUNCT
fnp-3025	1763	12	the	the	DET
fnp-3025	1763	13	multiplex	multiplex	PROPN
fnp-3025	1763	14	model	model	NOUN
fnp-3025	1763	15	of	of	ADP
fnp-3025	1763	16	the	the	DET
fnp-3025	1763	17	genetics	genetic	NOUN
fnp-3025	1763	18	of	of	ADP
fnp-3025	1763	19	alzheimer	alzheimer	PROPN
fnp-3025	1763	20	’s	’s	PART
fnp-3025	1763	21	disease	disease	NOUN
fnp-3025	1763	22	.	.	PUNCT
fnp-3025	1764	1	nat	nat	PROPN
fnp-3025	1764	2	neurosci	neurosci	PROPN
fnp-3025	1764	3	,	,	PUNCT
fnp-3025	1764	4	2020	2020	NUM
fnp-3025	1764	5	.	.	PUNCT
fnp-3025	1765	1	23(3	23(3	NUM
fnp-3025	1765	2	):	):	PUNCT
fnp-3025	1765	3	p.	p.	NOUN
fnp-3025	1765	4	311	311	NUM
fnp-3025	1765	5	-	-	SYM
fnp-3025	1765	6	322	322	NUM
fnp-3025	1765	7	.	.	NOUN
fnp-3025	1766	1	299	299	NUM
fnp-3025	1766	2	.	.	PUNCT
fnp-3025	1767	1	bohlen	bohlen	PROPN
fnp-3025	1767	2	,	,	PUNCT
fnp-3025	1767	3	c.j	c.j	PROPN
fnp-3025	1767	4	.	.	PROPN
fnp-3025	1767	5	,	,	PUNCT
fnp-3025	1767	6	et	et	PROPN
fnp-3025	1767	7	al	al	PROPN
fnp-3025	1767	8	.	.	PROPN
fnp-3025	1767	9	,	,	PUNCT
fnp-3025	1767	10	microglia	microglia	NOUN
fnp-3025	1767	11	in	in	ADP
fnp-3025	1767	12	brain	brain	NOUN
fnp-3025	1767	13	development	development	NOUN
fnp-3025	1767	14	,	,	PUNCT
fnp-3025	1767	15	homeostasis	homeostasis	NOUN
fnp-3025	1767	16	,	,	PUNCT
fnp-3025	1767	17	and	and	CCONJ
fnp-3025	1767	18	neurodegeneration	neurodegeneration	NOUN
fnp-3025	1767	19	.	.	PUNCT
fnp-3025	1768	1	annu	annu	PROPN
fnp-3025	1768	2	rev	rev	VERB
fnp-3025	1768	3	genet	genet	PROPN
fnp-3025	1768	4	,	,	PUNCT
fnp-3025	1768	5	2019	2019	NUM
fnp-3025	1768	6	.	.	PUNCT
fnp-3025	1769	1	53	53	NUM
fnp-3025	1769	2	:	:	PUNCT
fnp-3025	1769	3	p.	p.	NOUN
fnp-3025	1769	4	263	263	NUM
fnp-3025	1769	5	-	-	SYM
fnp-3025	1769	6	288	288	NUM
fnp-3025	1769	7	.	.	PUNCT
fnp-3025	1770	1	300	300	NUM
fnp-3025	1770	2	.	.	PUNCT
fnp-3025	1771	1	hansen	hansen	PROPN
fnp-3025	1771	2	,	,	PUNCT
fnp-3025	1771	3	d.v	d.v	PROPN
fnp-3025	1771	4	.	.	PROPN
fnp-3025	1771	5	,	,	PUNCT
fnp-3025	1771	6	j.e	j.e	PROPN
fnp-3025	1771	7	.	.	PROPN
fnp-3025	1771	8	hanson	hanson	PROPN
fnp-3025	1771	9	,	,	PUNCT
fnp-3025	1771	10	and	and	CCONJ
fnp-3025	1771	11	m.	m.	PROPN
fnp-3025	1771	12	sheng	sheng	PROPN
fnp-3025	1771	13	,	,	PUNCT
fnp-3025	1771	14	microglia	microglia	NOUN
fnp-3025	1771	15	in	in	ADP
fnp-3025	1771	16	alzheimer	alzheimer	PROPN
fnp-3025	1771	17	’s	’s	PART
fnp-3025	1771	18	disease	disease	NOUN
fnp-3025	1771	19	.	.	PUNCT
fnp-3025	1772	1	j	j	PROPN
fnp-3025	1772	2	cell	cell	PROPN
fnp-3025	1772	3	biol	biol	PROPN
fnp-3025	1772	4	,	,	PUNCT
fnp-3025	1772	5	2018	2018	NUM
fnp-3025	1772	6	.	.	PUNCT
fnp-3025	1773	1	217(2	217(2	NUM
fnp-3025	1773	2	):	):	PUNCT
fnp-3025	1773	3	p.	p.	NOUN
fnp-3025	1773	4	459	459	NUM
fnp-3025	1773	5	-	-	SYM
fnp-3025	1773	6	472	472	NUM
fnp-3025	1773	7	.	.	PUNCT
fnp-3025	1774	1	301	301	NUM
fnp-3025	1774	2	.	.	PUNCT
fnp-3025	1775	1	neuner	neuner	PROPN
fnp-3025	1775	2	,	,	PUNCT
fnp-3025	1775	3	s.m	s.m	PROPN
fnp-3025	1775	4	.	.	PROPN
fnp-3025	1775	5	,	,	PUNCT
fnp-3025	1775	6	j.	j.	PROPN
fnp-3025	1775	7	tcw	tcw	PROPN
fnp-3025	1775	8	,	,	PUNCT
fnp-3025	1775	9	and	and	CCONJ
fnp-3025	1775	10	a.m.	a.m.	PROPN
fnp-3025	1775	11	goate	goate	NOUN
fnp-3025	1775	12	,	,	PUNCT
fnp-3025	1775	13	genetic	genetic	ADJ
fnp-3025	1775	14	architecture	architecture	NOUN
fnp-3025	1775	15	of	of	ADP
fnp-3025	1775	16	alzheimer	alzheimer	PROPN
fnp-3025	1775	17	’s	’s	PART
fnp-3025	1775	18	disease	disease	NOUN
fnp-3025	1775	19	.	.	PUNCT
fnp-3025	1776	1	neurobiol	neurobiol	PROPN
fnp-3025	1776	2	dis	dis	PROPN
fnp-3025	1776	3	,	,	PUNCT
fnp-3025	1776	4	2020	2020	NUM
fnp-3025	1776	5	.	.	PUNCT
fnp-3025	1777	1	143	143	NUM
fnp-3025	1777	2	:	:	PUNCT
fnp-3025	1778	1	p.	p.	NOUN
fnp-3025	1778	2	104976	104976	NUM
fnp-3025	1778	3	.	.	PUNCT
fnp-3025	1779	1	302	302	NUM
fnp-3025	1779	2	.	.	PUNCT
fnp-3025	1779	3	farfara	farfara	PROPN
fnp-3025	1779	4	,	,	PUNCT
fnp-3025	1779	5	d.	d.	PROPN
fnp-3025	1779	6	,	,	PUNCT
fnp-3025	1779	7	v.	v.	ADP
fnp-3025	1779	8	lifshitz	lifshitz	PROPN
fnp-3025	1779	9	,	,	PUNCT
fnp-3025	1779	10	and	and	CCONJ
fnp-3025	1779	11	d.	d.	PROPN
fnp-3025	1779	12	frenkel	frenkel	PROPN
fnp-3025	1779	13	,	,	PUNCT
fnp-3025	1779	14	neuroprotective	neuroprotective	ADJ
fnp-3025	1779	15	and	and	CCONJ
fnp-3025	1779	16	neurotoxic	neurotoxic	ADJ
fnp-3025	1779	17	properties	property	NOUN
fnp-3025	1779	18	of	of	ADP
fnp-3025	1779	19	glial	glial	ADJ
fnp-3025	1779	20	cells	cell	NOUN
fnp-3025	1779	21	in	in	ADP
fnp-3025	1779	22	the	the	DET
fnp-3025	1779	23	pathogenesis	pathogenesis	NOUN
fnp-3025	1779	24	of	of	ADP
fnp-3025	1779	25	alzheimer	alzheimer	PROPN
fnp-3025	1779	26	’s	’s	PART
fnp-3025	1779	27	disease	disease	NOUN
fnp-3025	1779	28	.	.	PUNCT
fnp-3025	1780	1	j	j	PROPN
fnp-3025	1780	2	cell	cell	NOUN
fnp-3025	1780	3	mol	mol	ADP
fnp-3025	1780	4	med	med	PROPN
fnp-3025	1780	5	,	,	PUNCT
fnp-3025	1780	6	2008	2008	NUM
fnp-3025	1780	7	.	.	PUNCT
fnp-3025	1781	1	12(3	12(3	NUM
fnp-3025	1781	2	):	):	PUNCT
fnp-3025	1782	1	p.	p.	NOUN
fnp-3025	1782	2	762	762	NUM
fnp-3025	1782	3	-	-	SYM
fnp-3025	1782	4	80	80	NUM
fnp-3025	1782	5	.	.	PUNCT
fnp-3025	1782	6	303	303	NUM
fnp-3025	1782	7	.	.	PUNCT
fnp-3025	1783	1	liddelow	liddelow	NOUN
fnp-3025	1783	2	,	,	PUNCT
fnp-3025	1783	3	s.a	s.a	PROPN
fnp-3025	1783	4	.	.	PROPN
fnp-3025	1783	5	,	,	PUNCT
fnp-3025	1783	6	et	et	PROPN
fnp-3025	1783	7	al	al	PROPN
fnp-3025	1783	8	.	.	PROPN
fnp-3025	1783	9	,	,	PUNCT
fnp-3025	1783	10	neurotoxic	neurotoxic	ADJ
fnp-3025	1783	11	reactive	reactive	ADJ
fnp-3025	1783	12	astrocytes	astrocyte	NOUN
fnp-3025	1783	13	are	be	AUX
fnp-3025	1783	14	induced	induce	VERB
fnp-3025	1783	15	by	by	ADP
fnp-3025	1783	16	activated	activated	ADJ
fnp-3025	1783	17	microglia	microglia	NOUN
fnp-3025	1783	18	.	.	PUNCT
fnp-3025	1784	1	nature	nature	NOUN
fnp-3025	1784	2	,	,	PUNCT
fnp-3025	1784	3	2017	2017	NUM
fnp-3025	1784	4	.	.	PUNCT
fnp-3025	1785	1	541(7638	541(7638	NUM
fnp-3025	1785	2	):	):	PUNCT
fnp-3025	1786	1	p.	p.	NOUN
fnp-3025	1786	2	481	481	NUM
fnp-3025	1787	1	-	-	SYM
fnp-3025	1787	2	487	487	NUM
fnp-3025	1787	3	.	.	PUNCT
fnp-3025	1788	1	304	304	NUM
fnp-3025	1788	2	.	.	PUNCT
fnp-3025	1789	1	bouvier	bouvier	PROPN
fnp-3025	1789	2	,	,	PUNCT
fnp-3025	1789	3	d.s	d.s	PROPN
fnp-3025	1789	4	.	.	PROPN
fnp-3025	1789	5	and	and	CCONJ
fnp-3025	1789	6	k.k	k.k	PROPN
fnp-3025	1789	7	.	.	PROPN
fnp-3025	1789	8	murai	murai	PROPN
fnp-3025	1789	9	,	,	PUNCT
fnp-3025	1789	10	synergistic	synergistic	ADJ
fnp-3025	1789	11	actions	action	NOUN
fnp-3025	1789	12	of	of	ADP
fnp-3025	1789	13	microglia	microglia	NOUN
fnp-3025	1789	14	and	and	CCONJ
fnp-3025	1789	15	astrocytes	astrocyte	NOUN
fnp-3025	1789	16	in	in	ADP
fnp-3025	1789	17	the	the	DET
fnp-3025	1789	18	progression	progression	NOUN
fnp-3025	1789	19	of	of	ADP
fnp-3025	1789	20	alzheimer	alzheimer	PROPN
fnp-3025	1789	21	’s	’s	PART
fnp-3025	1789	22	disease	disease	NOUN
fnp-3025	1789	23	.	.	PUNCT
fnp-3025	1790	1	j	j	PROPN
fnp-3025	1790	2	alzheimers	alzheimers	PROPN
fnp-3025	1790	3	dis	dis	PROPN
fnp-3025	1790	4	,	,	PUNCT
fnp-3025	1790	5	2015	2015	NUM
fnp-3025	1790	6	.	.	PUNCT
fnp-3025	1791	1	45(4	45(4	NUM
fnp-3025	1791	2	):	):	PUNCT
fnp-3025	1792	1	p.	p.	NOUN
fnp-3025	1792	2	1001	1001	NUM
fnp-3025	1792	3	-	-	SYM
fnp-3025	1792	4	14	14	NUM
fnp-3025	1792	5	.	.	PUNCT
fnp-3025	1792	6	305	305	NUM
fnp-3025	1792	7	.	.	PUNCT
fnp-3025	1793	1	nichols	nichols	PROPN
fnp-3025	1793	2	,	,	PUNCT
fnp-3025	1793	3	m.r	m.r	PROPN
fnp-3025	1793	4	.	.	PROPN
fnp-3025	1793	5	,	,	PUNCT
fnp-3025	1793	6	et	et	PROPN
fnp-3025	1793	7	al	al	PROPN
fnp-3025	1793	8	.	.	PROPN
fnp-3025	1793	9	,	,	PUNCT
fnp-3025	1793	10	inflammatory	inflammatory	ADJ
fnp-3025	1793	11	mechanisms	mechanism	NOUN
fnp-3025	1793	12	in	in	ADP
fnp-3025	1793	13	neurodegeneration	neurodegeneration	NOUN
fnp-3025	1793	14	.	.	PUNCT
fnp-3025	1794	1	j	j	PROPN
fnp-3025	1794	2	neurochem	neurochem	PROPN
fnp-3025	1794	3	,	,	PUNCT
fnp-3025	1794	4	2019	2019	NUM
fnp-3025	1794	5	.	.	PUNCT
fnp-3025	1795	1	149(5	149(5	NUM
fnp-3025	1795	2	):	):	PUNCT
fnp-3025	1795	3	p.	p.	NOUN
fnp-3025	1795	4	562	562	NUM
fnp-3025	1795	5	-	-	SYM
fnp-3025	1795	6	581	581	NUM
fnp-3025	1795	7	.	.	PUNCT
fnp-3025	1795	8	306	306	NUM
fnp-3025	1795	9	.	.	PUNCT
fnp-3025	1796	1	schwabe	schwabe	NOUN
fnp-3025	1796	2	,	,	PUNCT
fnp-3025	1796	3	t.	t.	PROPN
fnp-3025	1796	4	,	,	PUNCT
fnp-3025	1796	5	k.	k.	PROPN
fnp-3025	1796	6	srinivasan	srinivasan	PROPN
fnp-3025	1796	7	,	,	PUNCT
fnp-3025	1796	8	and	and	CCONJ
fnp-3025	1796	9	h.	h.	PROPN
fnp-3025	1796	10	rhinn	rhinn	PROPN
fnp-3025	1796	11	,	,	PUNCT
fnp-3025	1796	12	shifting	shift	VERB
fnp-3025	1796	13	paradigms	paradigm	VERB
fnp-3025	1796	14	:	:	PUNCT
fnp-3025	1796	15	the	the	DET
fnp-3025	1796	16	central	central	ADJ
fnp-3025	1796	17	role	role	NOUN
fnp-3025	1796	18	of	of	ADP
fnp-3025	1796	19	microglia	microglia	NOUN
fnp-3025	1796	20	in	in	ADP
fnp-3025	1796	21	alzheimer	alzheimer	PROPN
fnp-3025	1796	22	’s	’s	PART
fnp-3025	1796	23	disease	disease	NOUN
fnp-3025	1796	24	.	.	PUNCT
fnp-3025	1797	1	neurobiol	neurobiol	PROPN
fnp-3025	1797	2	dis	dis	PROPN
fnp-3025	1797	3	,	,	PUNCT
fnp-3025	1797	4	2020	2020	NUM
fnp-3025	1797	5	.	.	PUNCT
fnp-3025	1798	1	143	143	NUM
fnp-3025	1798	2	:	:	PUNCT
fnp-3025	1799	1	p.	p.	NOUN
fnp-3025	1799	2	104962	104962	NUM
fnp-3025	1799	3	.	.	PUNCT
fnp-3025	1800	1	307	307	NUM
fnp-3025	1800	2	.	.	PUNCT
fnp-3025	1800	3	serrano	serrano	PROPN
fnp-3025	1800	4	-	-	PUNCT
fnp-3025	1800	5	pozo	pozo	PROPN
fnp-3025	1800	6	,	,	PUNCT
fnp-3025	1800	7	a.	a.	PROPN
fnp-3025	1800	8	,	,	PUNCT
fnp-3025	1800	9	et	et	PROPN
fnp-3025	1800	10	al	al	PROPN
fnp-3025	1800	11	.	.	PROPN
fnp-3025	1800	12	,	,	PUNCT
fnp-3025	1800	13	differential	differential	ADJ
fnp-3025	1800	14	relationships	relationship	NOUN
fnp-3025	1800	15	of	of	ADP
fnp-3025	1800	16	reactive	reactive	ADJ
fnp-3025	1800	17	astrocytes	astrocyte	NOUN
fnp-3025	1800	18	and	and	CCONJ
fnp-3025	1800	19	microglia	microglia	ADJ
fnp-3025	1800	20	to	to	ADP
fnp-3025	1800	21	fibrillar	fibrillar	ADJ
fnp-3025	1800	22	amyloid	amyloid	NOUN
fnp-3025	1800	23	deposits	deposit	NOUN
fnp-3025	1800	24	in	in	ADP
fnp-3025	1800	25	alzheimer	alzheimer	PROPN
fnp-3025	1800	26	disease	disease	PROPN
fnp-3025	1800	27	.	.	PUNCT
fnp-3025	1801	1	j	j	PROPN
fnp-3025	1801	2	neuropathol	neuropathol	PROPN
fnp-3025	1801	3	exp	exp	PROPN
fnp-3025	1801	4	neurol	neurol	PROPN
fnp-3025	1801	5	,	,	PUNCT
fnp-3025	1801	6	2013	2013	NUM
fnp-3025	1801	7	.	.	PUNCT
fnp-3025	1802	1	72(6	72(6	NUM
fnp-3025	1802	2	):	):	PUNCT
fnp-3025	1803	1	p.	p.	NOUN
fnp-3025	1803	2	462	462	NUM
fnp-3025	1804	1	-	-	SYM
fnp-3025	1804	2	71	71	NUM
fnp-3025	1804	3	.	.	PUNCT
fnp-3025	1805	1	308	308	NUM
fnp-3025	1805	2	.	.	X
fnp-3025	1805	3	town	town	NOUN
fnp-3025	1805	4	,	,	PUNCT
fnp-3025	1805	5	t.	t.	PROPN
fnp-3025	1805	6	,	,	PUNCT
fnp-3025	1805	7	v.	v.	CCONJ
fnp-3025	1805	8	nikolic	nikolic	PROPN
fnp-3025	1805	9	,	,	PUNCT
fnp-3025	1805	10	and	and	CCONJ
fnp-3025	1805	11	j.	j.	PROPN
fnp-3025	1805	12	tan	tan	PROPN
fnp-3025	1805	13	,	,	PUNCT
fnp-3025	1805	14	the	the	DET
fnp-3025	1805	15	microglial	microglial	ADJ
fnp-3025	1805	16	"	"	PUNCT
fnp-3025	1805	17	activation	activation	NOUN
fnp-3025	1805	18	"	"	PUNCT
fnp-3025	1805	19	continuum	continuum	NOUN
fnp-3025	1805	20	:	:	PUNCT
fnp-3025	1805	21	from	from	ADP
fnp-3025	1805	22	innate	innate	ADJ
fnp-3025	1805	23	to	to	ADP
fnp-3025	1805	24	adaptive	adaptive	ADJ
fnp-3025	1805	25	responses	response	NOUN
fnp-3025	1805	26	.	.	PUNCT
fnp-3025	1806	1	j	j	PROPN
fnp-3025	1806	2	neuroinflammation	neuroinflammation	PROPN
fnp-3025	1806	3	,	,	PUNCT
fnp-3025	1806	4	2005	2005	NUM
fnp-3025	1806	5	.	.	PUNCT
fnp-3025	1807	1	2	2	NUM
fnp-3025	1807	2	:	:	PUNCT
fnp-3025	1807	3	p.	p.	NOUN
fnp-3025	1807	4	24	24	NUM
fnp-3025	1807	5	.	.	PUNCT
fnp-3025	1807	6	309	309	NUM
fnp-3025	1807	7	.	.	PUNCT
fnp-3025	1808	1	wyss	wyss	NOUN
fnp-3025	1808	2	-	-	PUNCT
fnp-3025	1808	3	coray	coray	NOUN
fnp-3025	1808	4	,	,	PUNCT
fnp-3025	1808	5	t.	t.	PROPN
fnp-3025	1808	6	and	and	CCONJ
fnp-3025	1808	7	j.	j.	PROPN
fnp-3025	1808	8	rogers	rogers	PROPN
fnp-3025	1808	9	,	,	PUNCT
fnp-3025	1808	10	inflammation	inflammation	NOUN
fnp-3025	1808	11	in	in	ADP
fnp-3025	1808	12	alzheimer	alzheimer	PROPN
fnp-3025	1808	13	disease	disease	PROPN
fnp-3025	1808	14	-	-	PUNCT
fnp-3025	1808	15	a	a	DET
fnp-3025	1808	16	brief	brief	ADJ
fnp-3025	1808	17	review	review	NOUN
fnp-3025	1808	18	of	of	ADP
fnp-3025	1808	19	the	the	DET
fnp-3025	1808	20	basic	basic	ADJ
fnp-3025	1808	21	science	science	NOUN
fnp-3025	1808	22	and	and	CCONJ
fnp-3025	1808	23	clinical	clinical	ADJ
fnp-3025	1808	24	literature	literature	NOUN
fnp-3025	1808	25	.	.	PUNCT
fnp-3025	1809	1	cold	cold	ADJ
fnp-3025	1809	2	spring	spring	NOUN
fnp-3025	1809	3	harb	harb	PROPN
fnp-3025	1809	4	perspect	perspect	PROPN
fnp-3025	1809	5	med	me	VERB
fnp-3025	1809	6	,	,	PUNCT
fnp-3025	1809	7	2012	2012	NUM
fnp-3025	1809	8	.	.	PUNCT
fnp-3025	1810	1	2(1	2(1	NUM
fnp-3025	1810	2	):	):	PUNCT
fnp-3025	1810	3	p.	p.	PROPN
fnp-3025	1810	4	a006346	a006346	PROPN
fnp-3025	1810	5	.	.	PUNCT
fnp-3025	1811	1	310	310	NUM
fnp-3025	1811	2	.	.	X
fnp-3025	1812	1	johnson	johnson	PROPN
fnp-3025	1812	2	,	,	PUNCT
fnp-3025	1812	3	e.c.b	e.c.b	NOUN
fnp-3025	1812	4	.	.	PUNCT
fnp-3025	1812	5	,	,	PUNCT
fnp-3025	1812	6	et	et	PROPN
fnp-3025	1812	7	al	al	PROPN
fnp-3025	1812	8	.	.	PROPN
fnp-3025	1812	9	,	,	PUNCT
fnp-3025	1812	10	large	large	ADJ
fnp-3025	1812	11	-	-	PUNCT
fnp-3025	1812	12	scale	scale	NOUN
fnp-3025	1812	13	proteomic	proteomic	ADJ
fnp-3025	1812	14	analysis	analysis	NOUN
fnp-3025	1812	15	of	of	ADP
fnp-3025	1812	16	alzheimer	alzheimer	PROPN
fnp-3025	1812	17	’s	’s	PART
fnp-3025	1812	18	disease	disease	NOUN
fnp-3025	1812	19	brain	brain	NOUN
fnp-3025	1812	20	and	and	CCONJ
fnp-3025	1812	21	cerebrospinal	cerebrospinal	ADJ
fnp-3025	1812	22	fluid	fluid	NOUN
fnp-3025	1812	23	reveals	reveal	VERB
fnp-3025	1812	24	early	early	ADJ
fnp-3025	1812	25	changes	change	NOUN
fnp-3025	1812	26	in	in	ADP
fnp-3025	1812	27	energy	energy	NOUN
fnp-3025	1812	28	metabolism	metabolism	NOUN
fnp-3025	1812	29	associated	associate	VERB
fnp-3025	1812	30	with	with	ADP
fnp-3025	1812	31	microglia	microglia	ADJ
fnp-3025	1812	32	and	and	CCONJ
fnp-3025	1812	33	astrocyte	astrocyte	NOUN
fnp-3025	1812	34	activation	activation	NOUN
fnp-3025	1812	35	.	.	PUNCT
fnp-3025	1813	1	nat	nat	PROPN
fnp-3025	1813	2	med	med	PROPN
fnp-3025	1813	3	,	,	PUNCT
fnp-3025	1813	4	2020	2020	NUM
fnp-3025	1813	5	.	.	PUNCT
fnp-3025	1814	1	26(5	26(5	NUM
fnp-3025	1814	2	):	):	PUNCT
fnp-3025	1815	1	p.	p.	NOUN
fnp-3025	1815	2	769	769	NUM
fnp-3025	1815	3	-	-	SYM
fnp-3025	1815	4	780	780	NUM
fnp-3025	1815	5	.	.	PUNCT
fnp-3025	1815	6	311	311	NUM
fnp-3025	1815	7	.	.	PUNCT
fnp-3025	1816	1	nagele	nagele	PROPN
fnp-3025	1816	2	,	,	PUNCT
fnp-3025	1816	3	r.g	r.g	PROPN
fnp-3025	1816	4	.	.	PROPN
fnp-3025	1816	5	,	,	PUNCT
fnp-3025	1816	6	et	et	PROPN
fnp-3025	1816	7	al	al	PROPN
fnp-3025	1816	8	.	.	PROPN
fnp-3025	1816	9	,	,	PUNCT
fnp-3025	1816	10	contribution	contribution	NOUN
fnp-3025	1816	11	of	of	ADP
fnp-3025	1816	12	glial	glial	ADJ
fnp-3025	1816	13	cells	cell	NOUN
fnp-3025	1816	14	to	to	ADP
fnp-3025	1816	15	the	the	DET
fnp-3025	1816	16	development	development	NOUN
fnp-3025	1816	17	of	of	ADP
fnp-3025	1816	18	amyloid	amyloid	NOUN
fnp-3025	1816	19	plaques	plaque	NOUN
fnp-3025	1816	20	in	in	ADP
fnp-3025	1816	21	alzheimer	alzheimer	PROPN
fnp-3025	1816	22	’s	’s	PART
fnp-3025	1816	23	disease	disease	NOUN
fnp-3025	1816	24	.	.	PUNCT
fnp-3025	1817	1	neurobiol	neurobiol	PROPN
fnp-3025	1817	2	aging	aging	NOUN
fnp-3025	1817	3	,	,	PUNCT
fnp-3025	1817	4	2004	2004	NUM
fnp-3025	1817	5	.	.	PUNCT
fnp-3025	1818	1	25(5	25(5	NUM
fnp-3025	1818	2	):	):	PUNCT
fnp-3025	1819	1	p.	p.	NOUN
fnp-3025	1819	2	663	663	NUM
fnp-3025	1819	3	-	-	SYM
fnp-3025	1819	4	74	74	NUM
fnp-3025	1819	5	.	.	PUNCT
fnp-3025	1819	6	312	312	NUM
fnp-3025	1819	7	.	.	PUNCT
fnp-3025	1820	1	perez	perez	PROPN
fnp-3025	1820	2	-	-	PUNCT
fnp-3025	1820	3	nievas	nievas	PROPN
fnp-3025	1820	4	,	,	PUNCT
fnp-3025	1820	5	b.g	b.g	PROPN
fnp-3025	1820	6	.	.	PROPN
fnp-3025	1820	7	and	and	CCONJ
fnp-3025	1820	8	a.	a.	PROPN
fnp-3025	1820	9	serrano	serrano	PROPN
fnp-3025	1820	10	-	-	PUNCT
fnp-3025	1820	11	pozo	pozo	PROPN
fnp-3025	1820	12	,	,	PUNCT
fnp-3025	1820	13	deciphering	decipher	VERB
fnp-3025	1820	14	the	the	DET
fnp-3025	1820	15	astrocyte	astrocyte	NOUN
fnp-3025	1820	16	reaction	reaction	NOUN
fnp-3025	1820	17	in	in	ADP
fnp-3025	1820	18	alzheimer	alzheimer	PROPN
fnp-3025	1820	19	’s	’s	PART
fnp-3025	1820	20	disease	disease	NOUN
fnp-3025	1820	21	.	.	PUNCT
fnp-3025	1821	1	front	front	ADJ
fnp-3025	1821	2	aging	age	VERB
fnp-3025	1821	3	neurosci	neurosci	NOUN
fnp-3025	1821	4	,	,	PUNCT
fnp-3025	1821	5	2018	2018	NUM
fnp-3025	1821	6	.	.	PUNCT
fnp-3025	1822	1	10	10	NUM
fnp-3025	1822	2	:	:	PUNCT
fnp-3025	1822	3	p.	p.	NOUN
fnp-3025	1822	4	114	114	NUM
fnp-3025	1822	5	.	.	PUNCT
fnp-3025	1822	6	313	313	NUM
fnp-3025	1822	7	.	.	PUNCT
fnp-3025	1823	1	bouvier	bouvier	PROPN
fnp-3025	1823	2	,	,	PUNCT
fnp-3025	1823	3	d.s	d.s	PROPN
fnp-3025	1823	4	.	.	PROPN
fnp-3025	1823	5	,	,	PUNCT
fnp-3025	1823	6	et	et	PROPN
fnp-3025	1823	7	al	al	PROPN
fnp-3025	1823	8	.	.	PROPN
fnp-3025	1823	9	,	,	PUNCT
fnp-3025	1823	10	high	high	ADJ
fnp-3025	1823	11	resolution	resolution	NOUN
fnp-3025	1823	12	dissection	dissection	NOUN
fnp-3025	1823	13	of	of	ADP
fnp-3025	1823	14	reactive	reactive	ADJ
fnp-3025	1823	15	glial	glial	ADJ
fnp-3025	1823	16	nets	net	NOUN
fnp-3025	1823	17	in	in	ADP
fnp-3025	1823	18	alzheimer	alzheimer	PROPN
fnp-3025	1823	19	’s	’s	PART
fnp-3025	1823	20	disease	disease	NOUN
fnp-3025	1823	21	.	.	PUNCT
fnp-3025	1824	1	sci	sci	PROPN
fnp-3025	1824	2	rep	rep	PROPN
fnp-3025	1824	3	,	,	PUNCT
fnp-3025	1824	4	2016	2016	NUM
fnp-3025	1824	5	.	.	PUNCT
fnp-3025	1825	1	6	6	NUM
fnp-3025	1825	2	:	:	PUNCT
fnp-3025	1825	3	p.	p.	NOUN
fnp-3025	1825	4	24544	24544	NUM
fnp-3025	1825	5	.	.	PUNCT
fnp-3025	1826	1	314	314	X
fnp-3025	1826	2	.	.	PUNCT
fnp-3025	1827	1	smith	smith	PROPN
fnp-3025	1827	2	,	,	PUNCT
fnp-3025	1827	3	a.j	a.j	PROPN
fnp-3025	1827	4	.	.	PROPN
fnp-3025	1827	5	,	,	PUNCT
fnp-3025	1827	6	t.	t.	PROPN
fnp-3025	1827	7	duan	duan	PROPN
fnp-3025	1827	8	,	,	PUNCT
fnp-3025	1827	9	and	and	CCONJ
fnp-3025	1827	10	a.s	a.s	PROPN
fnp-3025	1827	11	.	.	PROPN
fnp-3025	1827	12	verkman	verkman	NOUN
fnp-3025	1827	13	,	,	PUNCT
fnp-3025	1827	14	aquaporin-4	aquaporin-4	PROPN
fnp-3025	1827	15	reduces	reduce	VERB
fnp-3025	1827	16	neuropathology	neuropathology	NOUN
fnp-3025	1827	17	in	in	ADP
fnp-3025	1827	18	a	a	DET
fnp-3025	1827	19	mouse	mouse	NOUN
fnp-3025	1827	20	model	model	NOUN
fnp-3025	1827	21	of	of	ADP
fnp-3025	1827	22	alzheimer	alzheimer	PROPN
fnp-3025	1827	23	’s	’s	PART
fnp-3025	1827	24	disease	disease	NOUN
fnp-3025	1827	25	by	by	ADP
fnp-3025	1827	26	remodeling	remodel	VERB
fnp-3025	1827	27	peri	peri	NOUN
fnp-3025	1827	28	-	-	PUNCT
fnp-3025	1827	29	plaque	plaque	NOUN
fnp-3025	1827	30	astrocyte	astrocyte	NOUN
fnp-3025	1827	31	structure	structure	NOUN
fnp-3025	1827	32	.	.	PUNCT
fnp-3025	1828	1	acta	acta	PROPN
fnp-3025	1828	2	neuropathol	neuropathol	PROPN
fnp-3025	1828	3	commun	commun	PROPN
fnp-3025	1828	4	,	,	PUNCT
fnp-3025	1828	5	2019	2019	NUM
fnp-3025	1828	6	.	.	PUNCT
fnp-3025	1829	1	7(1	7(1	NUM
fnp-3025	1829	2	):	):	PUNCT
fnp-3025	1829	3	p.	p.	NOUN
fnp-3025	1829	4	74	74	NUM
fnp-3025	1829	5	.	.	PUNCT
fnp-3025	1830	1	315	315	NUM
fnp-3025	1830	2	.	.	PUNCT
fnp-3025	1831	1	heppner	heppner	PROPN
fnp-3025	1831	2	,	,	PUNCT
fnp-3025	1831	3	f.l	f.l	PROPN
fnp-3025	1831	4	.	.	PROPN
fnp-3025	1831	5	,	,	PUNCT
fnp-3025	1831	6	r.m	r.m	PROPN
fnp-3025	1831	7	.	.	PROPN
fnp-3025	1831	8	ransohoff	ransohoff	PROPN
fnp-3025	1831	9	,	,	PUNCT
fnp-3025	1831	10	and	and	CCONJ
fnp-3025	1831	11	b.	b.	PROPN
fnp-3025	1831	12	becher	becher	PROPN
fnp-3025	1831	13	,	,	PUNCT
fnp-3025	1831	14	immune	immune	ADJ
fnp-3025	1831	15	attack	attack	NOUN
fnp-3025	1831	16	:	:	PUNCT
fnp-3025	1831	17	the	the	DET
fnp-3025	1831	18	role	role	NOUN
fnp-3025	1831	19	of	of	ADP
fnp-3025	1831	20	inflammation	inflammation	NOUN
fnp-3025	1831	21	in	in	ADP
fnp-3025	1831	22	alzheimer	alzheimer	PROPN
fnp-3025	1831	23	disease	disease	PROPN
fnp-3025	1831	24	.	.	PUNCT
fnp-3025	1832	1	nat	nat	PROPN
fnp-3025	1832	2	rev	rev	PROPN
fnp-3025	1832	3	neurosci	neurosci	PROPN
fnp-3025	1832	4	,	,	PUNCT
fnp-3025	1832	5	2015	2015	NUM
fnp-3025	1832	6	.	.	PUNCT
fnp-3025	1833	1	16(6	16(6	NUM
fnp-3025	1833	2	):	):	PUNCT
fnp-3025	1833	3	p.	p.	NOUN
fnp-3025	1833	4	358	358	NUM
fnp-3025	1833	5	-	-	SYM
fnp-3025	1833	6	72	72	NUM
fnp-3025	1833	7	.	.	PUNCT
fnp-3025	1834	1	316	316	NUM
fnp-3025	1834	2	.	.	PUNCT
fnp-3025	1835	1	garwood	garwood	PROPN
fnp-3025	1835	2	,	,	PUNCT
fnp-3025	1835	3	c.j	c.j	PROPN
fnp-3025	1835	4	.	.	PROPN
fnp-3025	1835	5	,	,	PUNCT
fnp-3025	1835	6	et	et	PROPN
fnp-3025	1835	7	al	al	PROPN
fnp-3025	1835	8	.	.	PROPN
fnp-3025	1835	9	,	,	PUNCT
fnp-3025	1835	10	review	review	NOUN
fnp-3025	1835	11	:	:	PUNCT
fnp-3025	1835	12	astrocytes	astrocyte	NOUN
fnp-3025	1835	13	in	in	ADP
fnp-3025	1835	14	alzheimer	alzheimer	PROPN
fnp-3025	1835	15	’s	’s	PART
fnp-3025	1835	16	disease	disease	NOUN
fnp-3025	1835	17	and	and	CCONJ
fnp-3025	1835	18	other	other	ADJ
fnp-3025	1835	19	age	age	NOUN
fnp-3025	1835	20	-	-	PUNCT
fnp-3025	1835	21	associated	associate	VERB
fnp-3025	1835	22	dementias	dementia	NOUN
fnp-3025	1835	23	:	:	PUNCT
fnp-3025	1835	24	a	a	DET
fnp-3025	1835	25	supporting	support	VERB
fnp-3025	1835	26	player	player	NOUN
fnp-3025	1835	27	with	with	ADP
fnp-3025	1835	28	a	a	DET
fnp-3025	1835	29	central	central	ADJ
fnp-3025	1835	30	role	role	NOUN
fnp-3025	1835	31	.	.	PUNCT
fnp-3025	1836	1	neuropathol	neuropathol	NOUN
fnp-3025	1836	2	appl	appl	PROPN
fnp-3025	1836	3	neurobiol	neurobiol	PROPN
fnp-3025	1836	4	,	,	PUNCT
fnp-3025	1836	5	2017	2017	NUM
fnp-3025	1836	6	.	.	PUNCT
fnp-3025	1837	1	43(4	43(4	NOUN
fnp-3025	1837	2	):	):	PUNCT
fnp-3025	1838	1	p.	p.	NOUN
fnp-3025	1838	2	281	281	NUM
fnp-3025	1838	3	-	-	SYM
fnp-3025	1838	4	298	298	NUM
fnp-3025	1838	5	.	.	NOUN
fnp-3025	1838	6	317	317	NUM
fnp-3025	1838	7	.	.	PUNCT
fnp-3025	1839	1	simpson	simpson	PROPN
fnp-3025	1839	2	,	,	PUNCT
fnp-3025	1839	3	j.e	j.e	PROPN
fnp-3025	1839	4	.	.	PROPN
fnp-3025	1839	5	,	,	PUNCT
fnp-3025	1839	6	et	et	PROPN
fnp-3025	1839	7	al	al	PROPN
fnp-3025	1839	8	.	.	PROPN
fnp-3025	1839	9	,	,	PUNCT
fnp-3025	1839	10	astrocyte	astrocyte	NOUN
fnp-3025	1839	11	phenotype	phenotype	NOUN
fnp-3025	1839	12	in	in	ADP
fnp-3025	1839	13	relation	relation	NOUN
fnp-3025	1839	14	to	to	ADP
fnp-3025	1839	15	alzheimer	alzheimer	ADJ
fnp-3025	1839	16	-	-	PUNCT
fnp-3025	1839	17	type	type	NOUN
fnp-3025	1839	18	pathology	pathology	NOUN
fnp-3025	1839	19	in	in	ADP
fnp-3025	1839	20	the	the	DET
fnp-3025	1839	21	ageing	age	VERB
fnp-3025	1839	22	brain	brain	NOUN
fnp-3025	1839	23	.	.	PUNCT
fnp-3025	1840	1	neurobiol	neurobiol	PROPN
fnp-3025	1840	2	aging	aging	NOUN
fnp-3025	1840	3	,	,	PUNCT
fnp-3025	1840	4	2010	2010	NUM
fnp-3025	1840	5	.	.	PUNCT
fnp-3025	1841	1	31(4	31(4	NUM
fnp-3025	1841	2	):	):	PUNCT
fnp-3025	1842	1	p.	p.	NOUN
fnp-3025	1842	2	578	578	NUM
fnp-3025	1842	3	-	-	SYM
fnp-3025	1842	4	90	90	NUM
fnp-3025	1842	5	.	.	PUNCT
fnp-3025	1842	6	318	318	NUM
fnp-3025	1842	7	.	.	PUNCT
fnp-3025	1843	1	mandrekar	mandrekar	PROPN
fnp-3025	1843	2	-	-	PUNCT
fnp-3025	1843	3	colucci	colucci	PROPN
fnp-3025	1843	4	,	,	PUNCT
fnp-3025	1843	5	s.	s.	PROPN
fnp-3025	1843	6	and	and	CCONJ
fnp-3025	1843	7	g.e	g.e	PROPN
fnp-3025	1843	8	.	.	PROPN
fnp-3025	1843	9	landreth	landreth	PROPN
fnp-3025	1843	10	,	,	PUNCT
fnp-3025	1843	11	microglia	microglia	NOUN
fnp-3025	1843	12	and	and	CCONJ
fnp-3025	1843	13	inflammation	inflammation	NOUN
fnp-3025	1843	14	in	in	ADP
fnp-3025	1843	15	alzheimer	alzheimer	PROPN
fnp-3025	1843	16	’s	’s	PART
fnp-3025	1843	17	disease	disease	NOUN
fnp-3025	1843	18	.	.	PUNCT
fnp-3025	1844	1	cns	cns	PROPN
fnp-3025	1844	2	neurol	neurol	PROPN
fnp-3025	1844	3	disord	disord	NOUN
fnp-3025	1844	4	drug	drug	NOUN
fnp-3025	1844	5	targets	target	NOUN
fnp-3025	1844	6	,	,	PUNCT
fnp-3025	1844	7	2010	2010	NUM
fnp-3025	1844	8	.	.	PUNCT
fnp-3025	1845	1	9(2	9(2	NUM
fnp-3025	1845	2	):	):	PUNCT
fnp-3025	1846	1	p.	p.	NOUN
fnp-3025	1846	2	156	156	NUM
fnp-3025	1846	3	-	-	SYM
fnp-3025	1846	4	67	67	NUM
fnp-3025	1846	5	.	.	PUNCT
fnp-3025	1846	6	319	319	NUM
fnp-3025	1846	7	.	.	PUNCT
fnp-3025	1847	1	galatro	galatro	PROPN
fnp-3025	1847	2	,	,	PUNCT
fnp-3025	1847	3	t.f	t.f	PROPN
fnp-3025	1847	4	.	.	PROPN
fnp-3025	1847	5	,	,	PUNCT
fnp-3025	1847	6	et	et	PROPN
fnp-3025	1847	7	al	al	PROPN
fnp-3025	1847	8	.	.	PROPN
fnp-3025	1847	9	,	,	PUNCT
fnp-3025	1847	10	transcriptomic	transcriptomic	ADJ
fnp-3025	1847	11	analysis	analysis	NOUN
fnp-3025	1847	12	of	of	ADP
fnp-3025	1847	13	purified	purified	ADJ
fnp-3025	1847	14	human	human	ADJ
fnp-3025	1847	15	cortical	cortical	ADJ
fnp-3025	1847	16	microglia	microglia	NOUN
fnp-3025	1847	17	reveals	reveal	VERB
fnp-3025	1847	18	age	age	NOUN
fnp-3025	1847	19	-	-	PUNCT
fnp-3025	1847	20	associated	associate	VERB
fnp-3025	1847	21	changes	change	NOUN
fnp-3025	1847	22	.	.	PUNCT
fnp-3025	1848	1	nat	nat	PROPN
fnp-3025	1848	2	neurosci	neurosci	PROPN
fnp-3025	1848	3	,	,	PUNCT
fnp-3025	1848	4	2017	2017	NUM
fnp-3025	1848	5	.	.	PUNCT
fnp-3025	1849	1	20(8	20(8	NUM
fnp-3025	1849	2	):	):	PUNCT
fnp-3025	1849	3	p.	p.	NOUN
fnp-3025	1849	4	1162	1162	NUM
fnp-3025	1849	5	-	-	SYM
fnp-3025	1849	6	1171	1171	NUM
fnp-3025	1849	7	.	.	PUNCT
fnp-3025	1850	1	320	320	NUM
fnp-3025	1850	2	.	.	PUNCT
fnp-3025	1851	1	zhou	zhou	PROPN
fnp-3025	1851	2	,	,	PUNCT
fnp-3025	1851	3	y.	y.	PROPN
fnp-3025	1851	4	,	,	PUNCT
fnp-3025	1851	5	et	et	PROPN
fnp-3025	1851	6	al	al	PROPN
fnp-3025	1851	7	.	.	PROPN
fnp-3025	1851	8	,	,	PUNCT
fnp-3025	1851	9	human	human	NOUN
fnp-3025	1851	10	and	and	CCONJ
fnp-3025	1851	11	mouse	mouse	PROPN
fnp-3025	1851	12	single	single	ADJ
fnp-3025	1851	13	-	-	PUNCT
fnp-3025	1851	14	nucleus	nucleus	NOUN
fnp-3025	1851	15	transcriptomics	transcriptomic	NOUN
fnp-3025	1851	16	reveal	reveal	VERB
fnp-3025	1851	17	trem2	trem2	NOUN
fnp-3025	1851	18	-	-	PUNCT
fnp-3025	1851	19	dependent	dependent	ADJ
fnp-3025	1851	20	and	and	CCONJ
fnp-3025	1851	21	trem2	trem2	NOUN
fnp-3025	1851	22	-	-	ADJ
fnp-3025	1851	23	independent	independent	ADJ
fnp-3025	1851	24	cellular	cellular	ADJ
fnp-3025	1851	25	responses	response	NOUN
fnp-3025	1851	26	in	in	ADP
fnp-3025	1851	27	alzheimer	alzheimer	PROPN
fnp-3025	1851	28	’s	’s	PART
fnp-3025	1851	29	disease	disease	NOUN
fnp-3025	1851	30	.	.	PUNCT
fnp-3025	1852	1	nat	nat	PROPN
fnp-3025	1852	2	med	med	PROPN
fnp-3025	1852	3	,	,	PUNCT
fnp-3025	1852	4	2020	2020	NUM
fnp-3025	1852	5	.	.	PUNCT
fnp-3025	1853	1	26(1	26(1	NUM
fnp-3025	1853	2	):	):	PUNCT
fnp-3025	1854	1	p.	p.	NOUN
fnp-3025	1854	2	131	131	NUM
fnp-3025	1854	3	-	-	SYM
fnp-3025	1854	4	142	142	NUM
fnp-3025	1854	5	.	.	PUNCT
fnp-3025	1854	6	321	321	NUM
fnp-3025	1854	7	.	.	PUNCT
fnp-3025	1855	1	baik	baik	PROPN
fnp-3025	1855	2	,	,	PUNCT
fnp-3025	1855	3	s.h	s.h	PROPN
fnp-3025	1855	4	.	.	PROPN
fnp-3025	1855	5	,	,	PUNCT
fnp-3025	1855	6	et	et	PROPN
fnp-3025	1855	7	al	al	PROPN
fnp-3025	1855	8	.	.	PROPN
fnp-3025	1855	9	,	,	PUNCT
fnp-3025	1855	10	microglia	microglia	NOUN
fnp-3025	1855	11	contributes	contribute	VERB
fnp-3025	1855	12	to	to	ADP
fnp-3025	1855	13	plaque	plaque	NOUN
fnp-3025	1855	14	growth	growth	NOUN
fnp-3025	1855	15	by	by	ADP
fnp-3025	1855	16	cell	cell	NOUN
fnp-3025	1855	17	death	death	NOUN
fnp-3025	1855	18	due	due	ADP
fnp-3025	1855	19	to	to	ADP
fnp-3025	1855	20	uptake	uptake	ADJ
fnp-3025	1855	21	of	of	ADP
fnp-3025	1855	22	amyloid	amyloid	NOUN
fnp-3025	1855	23	beta	beta	NOUN
fnp-3025	1855	24	in	in	ADP
fnp-3025	1855	25	the	the	DET
fnp-3025	1855	26	brain	brain	NOUN
fnp-3025	1855	27	of	of	ADP
fnp-3025	1855	28	alzheimer	alzheimer	PROPN
fnp-3025	1855	29	’s	’s	PART
fnp-3025	1855	30	disease	disease	PROPN
fnp-3025	1855	31	mouse	mouse	NOUN
fnp-3025	1855	32	model	model	NOUN
fnp-3025	1855	33	.	.	PUNCT
fnp-3025	1856	1	glia	glia	PROPN
fnp-3025	1856	2	,	,	PUNCT
fnp-3025	1856	3	2016	2016	NUM
fnp-3025	1856	4	.	.	PUNCT
fnp-3025	1857	1	64(12	64(12	NUM
fnp-3025	1857	2	):	):	PUNCT
fnp-3025	1857	3	p.	p.	NOUN
fnp-3025	1857	4	2274	2274	NUM
fnp-3025	1857	5	-	-	SYM
fnp-3025	1857	6	2290	2290	NUM
fnp-3025	1857	7	.	.	PUNCT
fnp-3025	1858	1	322	322	NUM
fnp-3025	1858	2	.	.	NOUN
fnp-3025	1858	3	bolmont	bolmont	NOUN
fnp-3025	1858	4	,	,	PUNCT
fnp-3025	1858	5	t.	t.	PROPN
fnp-3025	1858	6	,	,	PUNCT
fnp-3025	1858	7	et	et	PROPN
fnp-3025	1858	8	al	al	PROPN
fnp-3025	1858	9	.	.	PROPN
fnp-3025	1858	10	,	,	PUNCT
fnp-3025	1858	11	dynamics	dynamic	NOUN
fnp-3025	1858	12	of	of	ADP
fnp-3025	1858	13	the	the	DET
fnp-3025	1858	14	microglial	microglial	ADJ
fnp-3025	1858	15	/	/	SYM
fnp-3025	1858	16	amyloid	amyloid	NOUN
fnp-3025	1858	17	interaction	interaction	NOUN
fnp-3025	1858	18	indicate	indicate	VERB
fnp-3025	1858	19	a	a	DET
fnp-3025	1858	20	role	role	NOUN
fnp-3025	1858	21	in	in	ADP
fnp-3025	1858	22	plaque	plaque	NOUN
fnp-3025	1858	23	maintenance	maintenance	NOUN
fnp-3025	1858	24	.	.	PUNCT
fnp-3025	1859	1	j	j	PROPN
fnp-3025	1859	2	neurosci	neurosci	PROPN
fnp-3025	1859	3	,	,	PUNCT
fnp-3025	1859	4	2008	2008	NUM
fnp-3025	1859	5	.	.	PUNCT
fnp-3025	1860	1	28(16	28(16	NUM
fnp-3025	1860	2	):	):	PUNCT
fnp-3025	1860	3	p.	p.	NOUN
fnp-3025	1860	4	4283	4283	NUM
fnp-3025	1860	5	-	-	SYM
fnp-3025	1860	6	92	92	NUM
fnp-3025	1860	7	.	.	PUNCT
fnp-3025	1861	1	323	323	NUM
fnp-3025	1861	2	.	.	PUNCT
fnp-3025	1862	1	fuger	fuger	NOUN
fnp-3025	1862	2	,	,	PUNCT
fnp-3025	1862	3	p.	p.	PROPN
fnp-3025	1862	4	,	,	PUNCT
fnp-3025	1862	5	et	et	PROPN
fnp-3025	1862	6	al	al	PROPN
fnp-3025	1862	7	.	.	PROPN
fnp-3025	1862	8	,	,	PUNCT
fnp-3025	1862	9	microglia	microglia	ADJ
fnp-3025	1862	10	turnover	turnover	NOUN
fnp-3025	1862	11	with	with	ADP
fnp-3025	1862	12	aging	aging	NOUN
fnp-3025	1862	13	and	and	CCONJ
fnp-3025	1862	14	in	in	ADP
fnp-3025	1862	15	an	an	DET
fnp-3025	1862	16	alzheimer	alzheimer	NOUN
fnp-3025	1862	17	’s	’s	PART
fnp-3025	1862	18	model	model	NOUN
fnp-3025	1862	19	via	via	ADP
fnp-3025	1862	20	long	long	ADJ
fnp-3025	1862	21	-	-	PUNCT
fnp-3025	1862	22	term	term	NOUN
fnp-3025	1862	23	in	in	ADP
fnp-3025	1862	24	vivo	vivo	ADJ
fnp-3025	1862	25	single	single	ADJ
fnp-3025	1862	26	-	-	PUNCT
fnp-3025	1862	27	cell	cell	NOUN
fnp-3025	1862	28	imaging	imaging	NOUN
fnp-3025	1862	29	.	.	PUNCT
fnp-3025	1863	1	nat	nat	PROPN
fnp-3025	1863	2	neurosci	neurosci	PROPN
fnp-3025	1863	3	,	,	PUNCT
fnp-3025	1863	4	2017	2017	NUM
fnp-3025	1863	5	.	.	PUNCT
fnp-3025	1864	1	20(10	20(10	NUM
fnp-3025	1864	2	):	):	PUNCT
fnp-3025	1864	3	p.	p.	NOUN
fnp-3025	1864	4	1371	1371	NUM
fnp-3025	1864	5	-	-	SYM
fnp-3025	1864	6	1376	1376	NUM
fnp-3025	1864	7	.	.	PUNCT
fnp-3025	1865	1	324	324	NUM
fnp-3025	1865	2	.	.	X
fnp-3025	1865	3	hefendehl	hefendehl	NOUN
fnp-3025	1865	4	,	,	PUNCT
fnp-3025	1865	5	j.k	j.k	PROPN
fnp-3025	1865	6	.	.	PROPN
fnp-3025	1865	7	,	,	PUNCT
fnp-3025	1865	8	et	et	PROPN
fnp-3025	1865	9	al	al	PROPN
fnp-3025	1865	10	.	.	PROPN
fnp-3025	1865	11	,	,	PUNCT
fnp-3025	1865	12	long	long	ADJ
fnp-3025	1865	13	-	-	PUNCT
fnp-3025	1865	14	term	term	NOUN
fnp-3025	1865	15	in	in	ADP
fnp-3025	1865	16	vivo	vivo	ADJ
fnp-3025	1865	17	imaging	imaging	NOUN
fnp-3025	1865	18	of	of	ADP
fnp-3025	1865	19	beta	beta	NOUN
fnp-3025	1865	20	-	-	PUNCT
fnp-3025	1865	21	amyloid	amyloid	NOUN
fnp-3025	1865	22	plaque	plaque	NOUN
fnp-3025	1865	23	appearance	appearance	NOUN
fnp-3025	1865	24	and	and	CCONJ
fnp-3025	1865	25	growth	growth	NOUN
fnp-3025	1865	26	in	in	ADP
fnp-3025	1865	27	a	a	DET
fnp-3025	1865	28	mouse	mouse	NOUN
fnp-3025	1865	29	model	model	NOUN
fnp-3025	1865	30	of	of	ADP
fnp-3025	1865	31	cerebral	cerebral	ADJ
fnp-3025	1865	32	beta	beta	NOUN
fnp-3025	1865	33	-	-	PUNCT
fnp-3025	1865	34	amyloidosis	amyloidosis	NOUN
fnp-3025	1865	35	.	.	PUNCT
fnp-3025	1866	1	j	j	PROPN
fnp-3025	1866	2	neurosci	neurosci	PROPN
fnp-3025	1866	3	,	,	PUNCT
fnp-3025	1866	4	2011	2011	NUM
fnp-3025	1866	5	.	.	PUNCT
fnp-3025	1867	1	31(2	31(2	NUM
fnp-3025	1867	2	):	):	PUNCT
fnp-3025	1868	1	p.	p.	NOUN
fnp-3025	1868	2	624	624	NUM
fnp-3025	1868	3	-	-	SYM
fnp-3025	1868	4	9	9	NUM
fnp-3025	1868	5	.	.	NUM
fnp-3025	1868	6	325	325	NUM
fnp-3025	1868	7	.	.	PUNCT
fnp-3025	1869	1	ahmad	ahmad	PROPN
fnp-3025	1869	2	,	,	PUNCT
fnp-3025	1869	3	m.h	m.h	PROPN
fnp-3025	1869	4	.	.	PROPN
fnp-3025	1869	5	,	,	PUNCT
fnp-3025	1869	6	m.	m.	PROPN
fnp-3025	1869	7	fatima	fatima	PROPN
fnp-3025	1869	8	,	,	PUNCT
fnp-3025	1869	9	and	and	CCONJ
fnp-3025	1869	10	a.c	a.c	PROPN
fnp-3025	1869	11	.	.	PROPN
fnp-3025	1869	12	mondal	mondal	PROPN
fnp-3025	1869	13	,	,	PUNCT
fnp-3025	1869	14	influence	influence	NOUN
fnp-3025	1869	15	of	of	ADP
fnp-3025	1869	16	microglia	microglia	ADJ
fnp-3025	1869	17	and	and	CCONJ
fnp-3025	1869	18	astrocyte	astrocyte	NOUN
fnp-3025	1869	19	activation	activation	NOUN
fnp-3025	1869	20	in	in	ADP
fnp-3025	1869	21	the	the	DET
fnp-3025	1869	22	neuroinflammatory	neuroinflammatory	ADJ
fnp-3025	1869	23	pathogenesis	pathogenesis	NOUN
fnp-3025	1869	24	of	of	ADP
fnp-3025	1869	25	alzheimer	alzheimer	PROPN
fnp-3025	1869	26	’s	’s	PART
fnp-3025	1869	27	disease	disease	NOUN
fnp-3025	1869	28	:	:	PUNCT
fnp-3025	1869	29	rational	rational	ADJ
fnp-3025	1869	30	insights	insight	NOUN
fnp-3025	1869	31	for	for	ADP
fnp-3025	1869	32	the	the	DET
fnp-3025	1869	33	therapeutic	therapeutic	ADJ
fnp-3025	1869	34	approaches	approach	NOUN
fnp-3025	1869	35	.	.	PUNCT
fnp-3025	1870	1	j	j	PROPN
fnp-3025	1870	2	clin	clin	PROPN
fnp-3025	1870	3	neurosci	neurosci	PROPN
fnp-3025	1870	4	,	,	PUNCT
fnp-3025	1870	5	2019	2019	NUM
fnp-3025	1870	6	.	.	PUNCT
fnp-3025	1871	1	59	59	NUM
fnp-3025	1871	2	:	:	PUNCT
fnp-3025	1871	3	p.	p.	NOUN
fnp-3025	1871	4	6	6	NUM
fnp-3025	1871	5	-	-	SYM
fnp-3025	1871	6	11	11	NUM
fnp-3025	1871	7	.	.	PUNCT
fnp-3025	1872	1	326	326	NUM
fnp-3025	1872	2	.	.	X
fnp-3025	1873	1	frost	frost	NOUN
fnp-3025	1873	2	,	,	PUNCT
fnp-3025	1873	3	g.r	g.r	PROPN
fnp-3025	1873	4	.	.	PROPN
fnp-3025	1873	5	,	,	PUNCT
fnp-3025	1873	6	l.a	l.a	PROPN
fnp-3025	1873	7	.	.	PROPN
fnp-3025	1873	8	jonas	jonas	PROPN
fnp-3025	1873	9	,	,	PUNCT
fnp-3025	1873	10	and	and	CCONJ
fnp-3025	1873	11	y.m	y.m	PROPN
fnp-3025	1873	12	.	.	PROPN
fnp-3025	1873	13	li	li	PROPN
fnp-3025	1873	14	,	,	PUNCT
fnp-3025	1873	15	friend	friend	NOUN
fnp-3025	1873	16	,	,	PUNCT
fnp-3025	1873	17	foe	foe	NOUN
fnp-3025	1873	18	or	or	CCONJ
fnp-3025	1873	19	both	both	DET
fnp-3025	1873	20	?	?	PUNCT
fnp-3025	1873	21	immune	immune	ADJ
fnp-3025	1873	22	activity	activity	NOUN
fnp-3025	1873	23	in	in	ADP
fnp-3025	1873	24	alzheimer	alzheimer	PROPN
fnp-3025	1873	25	’s	’s	PART
fnp-3025	1873	26	disease	disease	NOUN
fnp-3025	1873	27	.	.	PUNCT
fnp-3025	1874	1	front	front	ADJ
fnp-3025	1874	2	aging	age	VERB
fnp-3025	1874	3	neurosci	neurosci	NOUN
fnp-3025	1874	4	,	,	PUNCT
fnp-3025	1874	5	2019	2019	NUM
fnp-3025	1874	6	.	.	PUNCT
fnp-3025	1875	1	11	11	NUM
fnp-3025	1875	2	:	:	PUNCT
fnp-3025	1876	1	p.	p.	NOUN
fnp-3025	1876	2	337	337	NUM
fnp-3025	1876	3	.	.	PUNCT
fnp-3025	1876	4	327	327	NUM
fnp-3025	1876	5	.	.	PUNCT
fnp-3025	1877	1	itagaki	itagaki	PROPN
fnp-3025	1877	2	,	,	PUNCT
fnp-3025	1877	3	s.	s.	PROPN
fnp-3025	1877	4	,	,	PUNCT
fnp-3025	1877	5	et	et	PROPN
fnp-3025	1877	6	al	al	PROPN
fnp-3025	1877	7	.	.	PROPN
fnp-3025	1877	8	,	,	PUNCT
fnp-3025	1877	9	relationship	relationship	NOUN
fnp-3025	1877	10	of	of	ADP
fnp-3025	1877	11	microglia	microglia	NOUN
fnp-3025	1877	12	and	and	CCONJ
fnp-3025	1877	13	astrocytes	astrocyte	NOUN
fnp-3025	1877	14	to	to	PART
fnp-3025	1877	15	amyloid	amyloid	NOUN
fnp-3025	1877	16	deposits	deposit	NOUN
fnp-3025	1877	17	of	of	ADP
fnp-3025	1877	18	alzheimer	alzheimer	PROPN
fnp-3025	1877	19	disease	disease	PROPN
fnp-3025	1877	20	.	.	PUNCT
fnp-3025	1878	1	j	j	PROPN
fnp-3025	1878	2	neuroimmunol	neuroimmunol	PROPN
fnp-3025	1878	3	,	,	PUNCT
fnp-3025	1878	4	1989	1989	NUM
fnp-3025	1878	5	.	.	PUNCT
fnp-3025	1879	1	24(3	24(3	NUM
fnp-3025	1879	2	):	):	PUNCT
fnp-3025	1880	1	p.	p.	NOUN
fnp-3025	1880	2	173	173	NUM
fnp-3025	1880	3	-	-	SYM
fnp-3025	1880	4	82	82	NUM
fnp-3025	1880	5	.	.	PUNCT
fnp-3025	1880	6	328	328	NUM
fnp-3025	1880	7	.	.	PUNCT
fnp-3025	1881	1	mrak	mrak	PROPN
fnp-3025	1881	2	,	,	PUNCT
fnp-3025	1881	3	r.e	r.e	PROPN
fnp-3025	1881	4	.	.	PROPN
fnp-3025	1881	5	,	,	PUNCT
fnp-3025	1881	6	neuropathology	neuropathology	NOUN
fnp-3025	1881	7	and	and	CCONJ
fnp-3025	1881	8	the	the	DET
fnp-3025	1881	9	neuroinflammation	neuroinflammation	NOUN
fnp-3025	1881	10	idea	idea	NOUN
fnp-3025	1881	11	.	.	PUNCT
fnp-3025	1882	1	j	j	PROPN
fnp-3025	1882	2	alzheimers	alzheimers	PROPN
fnp-3025	1882	3	dis	dis	PROPN
fnp-3025	1882	4	,	,	PUNCT
fnp-3025	1882	5	2009	2009	NUM
fnp-3025	1882	6	.	.	PUNCT
fnp-3025	1883	1	18(3	18(3	NUM
fnp-3025	1883	2	):	):	PUNCT
fnp-3025	1884	1	p.	p.	NOUN
fnp-3025	1884	2	473	473	NUM
fnp-3025	1884	3	-	-	SYM
fnp-3025	1884	4	81	81	NUM
fnp-3025	1884	5	.	.	PUNCT
fnp-3025	1884	6	329	329	NUM
fnp-3025	1884	7	.	.	PUNCT
fnp-3025	1885	1	sheng	sheng	PROPN
fnp-3025	1885	2	,	,	PUNCT
fnp-3025	1885	3	j.g	j.g	PROPN
fnp-3025	1885	4	.	.	PROPN
fnp-3025	1885	5	,	,	PUNCT
fnp-3025	1885	6	r.e	r.e	PROPN
fnp-3025	1885	7	.	.	PROPN
fnp-3025	1885	8	mrak	mrak	PROPN
fnp-3025	1885	9	,	,	PUNCT
fnp-3025	1885	10	and	and	CCONJ
fnp-3025	1885	11	w.s	w.s	PROPN
fnp-3025	1885	12	.	.	PROPN
fnp-3025	1885	13	griffin	griffin	PROPN
fnp-3025	1885	14	,	,	PUNCT
fnp-3025	1885	15	neuritic	neuritic	ADJ
fnp-3025	1885	16	plaque	plaque	NOUN
fnp-3025	1885	17	evolution	evolution	NOUN
fnp-3025	1885	18	in	in	ADP
fnp-3025	1885	19	alzheimer	alzheimer	PROPN
fnp-3025	1885	20	’s	’s	PART
fnp-3025	1885	21	disease	disease	NOUN
fnp-3025	1885	22	is	be	AUX
fnp-3025	1885	23	accompanied	accompany	VERB
fnp-3025	1885	24	by	by	ADP
fnp-3025	1885	25	transition	transition	NOUN
fnp-3025	1885	26	of	of	ADP
fnp-3025	1885	27	activated	activate	VERB
fnp-3025	1885	28	microglia	microglia	NOUN
fnp-3025	1885	29	from	from	ADP
fnp-3025	1885	30	primed	prime	VERB
fnp-3025	1885	31	to	to	PART
fnp-3025	1885	32	enlarged	enlarge	VERB
fnp-3025	1885	33	to	to	ADP
fnp-3025	1885	34	phagocytic	phagocytic	ADJ
fnp-3025	1885	35	forms	form	NOUN
fnp-3025	1885	36	.	.	PUNCT
fnp-3025	1886	1	acta	acta	PROPN
fnp-3025	1886	2	neuropathol	neuropathol	PROPN
fnp-3025	1886	3	,	,	PUNCT
fnp-3025	1886	4	1997	1997	NUM
fnp-3025	1886	5	.	.	PUNCT
fnp-3025	1887	1	94(1	94(1	NUM
fnp-3025	1887	2	):	):	PUNCT
fnp-3025	1887	3	p.	p.	NOUN
fnp-3025	1887	4	1	1	NUM
fnp-3025	1887	5	-	-	SYM
fnp-3025	1887	6	5	5	NUM
fnp-3025	1887	7	.	.	NUM
fnp-3025	1887	8	330	330	NUM
fnp-3025	1887	9	.	.	PUNCT
fnp-3025	1888	1	vonsattel	vonsattel	PROPN
fnp-3025	1888	2	,	,	PUNCT
fnp-3025	1888	3	j.p	j.p	PROPN
fnp-3025	1888	4	.	.	PROPN
fnp-3025	1888	5	and	and	CCONJ
fnp-3025	1888	6	e.t	e.t	PROPN
fnp-3025	1888	7	.	.	PROPN
fnp-3025	1888	8	hedley	hedley	PROPN
fnp-3025	1888	9	-	-	PUNCT
fnp-3025	1888	10	whyte	whyte	PROPN
fnp-3025	1888	11	,	,	PUNCT
fnp-3025	1888	12	dementia	dementia	NOUN
fnp-3025	1888	13	,	,	PUNCT
fnp-3025	1888	14	in	in	ADP
fnp-3025	1888	15	pathology	pathology	NOUN
fnp-3025	1888	16	of	of	ADP
fnp-3025	1888	17	the	the	DET
fnp-3025	1888	18	aging	age	VERB
fnp-3025	1888	19	human	human	ADJ
fnp-3025	1888	20	nervous	nervous	ADJ
fnp-3025	1888	21	system	system	NOUN
fnp-3025	1888	22	,	,	PUNCT
fnp-3025	1888	23	s.	s.	PROPN
fnp-3025	1888	24	duckett	duckett	PROPN
fnp-3025	1888	25	and	and	CCONJ
fnp-3025	1888	26	j.c	j.c	PROPN
fnp-3025	1888	27	.	.	PROPN
fnp-3025	1888	28	de	de	PROPN
fnp-3025	1888	29	la	la	X
fnp-3025	1888	30	torre	torre	PROPN
fnp-3025	1888	31	,	,	PUNCT
fnp-3025	1888	32	editors	editor	NOUN
fnp-3025	1888	33	.	.	PUNCT
fnp-3025	1889	1	2001	2001	NUM
fnp-3025	1889	2	,	,	PUNCT
fnp-3025	1889	3	oxford	oxford	PROPN
fnp-3025	1889	4	university	university	PROPN
fnp-3025	1889	5	press	press	NOUN
fnp-3025	1889	6	:	:	PUNCT
fnp-3025	1889	7	new	new	PROPN
fnp-3025	1889	8	york	york	PROPN
fnp-3025	1889	9	.	.	PUNCT
fnp-3025	1890	1	p.	p.	NOUN
fnp-3025	1890	2	156	156	NUM
fnp-3025	1891	1	-	-	SYM
fnp-3025	1891	2	206	206	NUM
fnp-3025	1891	3	.	.	PUNCT
fnp-3025	1892	1	331	331	NUM
fnp-3025	1892	2	.	.	PUNCT
fnp-3025	1893	1	gratuze	gratuze	PROPN
fnp-3025	1893	2	,	,	PUNCT
fnp-3025	1893	3	m.	m.	NOUN
fnp-3025	1893	4	,	,	PUNCT
fnp-3025	1893	5	c.e.g	c.e.g	PROPN
fnp-3025	1893	6	.	.	PROPN
fnp-3025	1893	7	leyns	leyns	PROPN
fnp-3025	1893	8	,	,	PUNCT
fnp-3025	1893	9	and	and	CCONJ
fnp-3025	1893	10	d.m	d.m	PROPN
fnp-3025	1893	11	.	.	PROPN
fnp-3025	1893	12	holtzman	holtzman	PROPN
fnp-3025	1893	13	,	,	PUNCT
fnp-3025	1893	14	new	new	ADJ
fnp-3025	1893	15	insights	insight	NOUN
fnp-3025	1893	16	into	into	ADP
fnp-3025	1893	17	the	the	DET
fnp-3025	1893	18	role	role	NOUN
fnp-3025	1893	19	of	of	ADP
fnp-3025	1893	20	trem2	trem2	NOUN
fnp-3025	1893	21	in	in	ADP
fnp-3025	1893	22	alzheimer	alzheimer	PROPN
fnp-3025	1893	23	’s	’s	PART
fnp-3025	1893	24	disease	disease	NOUN
fnp-3025	1893	25	.	.	PUNCT
fnp-3025	1894	1	mol	mol	ADP
fnp-3025	1894	2	neurodegener	neurodegener	NOUN
fnp-3025	1894	3	,	,	PUNCT
fnp-3025	1894	4	2018	2018	NUM
fnp-3025	1894	5	.	.	PUNCT
fnp-3025	1895	1	13(1	13(1	X
fnp-3025	1895	2	):	):	PUNCT
fnp-3025	1895	3	p.	p.	NOUN
fnp-3025	1895	4	66	66	NUM
fnp-3025	1895	5	.	.	PUNCT
fnp-3025	1896	1	332	332	NUM
fnp-3025	1896	2	.	.	PUNCT
fnp-3025	1897	1	yeh	yeh	PROPN
fnp-3025	1897	2	,	,	PUNCT
fnp-3025	1897	3	f.l	f.l	PROPN
fnp-3025	1897	4	.	.	PROPN
fnp-3025	1897	5	,	,	PUNCT
fnp-3025	1897	6	d.v	d.v	PROPN
fnp-3025	1897	7	.	.	PROPN
fnp-3025	1897	8	hansen	hansen	PROPN
fnp-3025	1897	9	,	,	PUNCT
fnp-3025	1897	10	and	and	CCONJ
fnp-3025	1897	11	m.	m.	PROPN
fnp-3025	1897	12	sheng	sheng	PROPN
fnp-3025	1897	13	,	,	PUNCT
fnp-3025	1897	14	trem2	trem2	NOUN
fnp-3025	1897	15	,	,	PUNCT
fnp-3025	1897	16	microglia	microglia	ADJ
fnp-3025	1897	17	,	,	PUNCT
fnp-3025	1897	18	and	and	CCONJ
fnp-3025	1897	19	neurodegenerative	neurodegenerative	ADJ
fnp-3025	1897	20	diseases	disease	NOUN
fnp-3025	1897	21	.	.	PUNCT
fnp-3025	1898	1	trends	trend	NOUN
fnp-3025	1898	2	mol	mol	ADP
fnp-3025	1898	3	med	med	ADJ
fnp-3025	1898	4	,	,	PUNCT
fnp-3025	1898	5	2017	2017	NUM
fnp-3025	1898	6	.	.	PUNCT
fnp-3025	1899	1	23(6	23(6	NUM
fnp-3025	1899	2	):	):	PUNCT
fnp-3025	1900	1	p.	p.	NOUN
fnp-3025	1900	2	512	512	NUM
fnp-3025	1900	3	-	-	SYM
fnp-3025	1900	4	533	533	NUM
fnp-3025	1900	5	.	.	NOUN
fnp-3025	1900	6	333	333	NUM
fnp-3025	1900	7	.	.	PUNCT
fnp-3025	1901	1	el	el	PROPN
fnp-3025	1901	2	khoury	khoury	PROPN
fnp-3025	1901	3	,	,	PUNCT
fnp-3025	1901	4	j.	j.	PROPN
fnp-3025	1901	5	,	,	PUNCT
fnp-3025	1901	6	et	et	PROPN
fnp-3025	1901	7	al	al	PROPN
fnp-3025	1901	8	.	.	PROPN
fnp-3025	1901	9	,	,	PUNCT
fnp-3025	1901	10	ccr2	ccr2	NOUN
fnp-3025	1901	11	deficiency	deficiency	NOUN
fnp-3025	1901	12	impairs	impair	VERB
fnp-3025	1901	13	microglial	microglial	ADJ
fnp-3025	1901	14	accumulation	accumulation	NOUN
fnp-3025	1901	15	and	and	CCONJ
fnp-3025	1901	16	accelerates	accelerate	VERB
fnp-3025	1901	17	progression	progression	NOUN
fnp-3025	1901	18	of	of	ADP
fnp-3025	1901	19	alzheimer	alzheimer	PROPN
fnp-3025	1901	20	-	-	PUNCT
fnp-3025	1901	21	like	like	ADJ
fnp-3025	1901	22	disease	disease	NOUN
fnp-3025	1901	23	.	.	PUNCT
fnp-3025	1902	1	nat	nat	PROPN
fnp-3025	1902	2	med	med	PROPN
fnp-3025	1902	3	,	,	PUNCT
fnp-3025	1902	4	2007	2007	NUM
fnp-3025	1902	5	.	.	PUNCT
fnp-3025	1903	1	13(4	13(4	NUM
fnp-3025	1903	2	):	):	PUNCT
fnp-3025	1904	1	p.	p.	NOUN
fnp-3025	1904	2	432	432	NUM
fnp-3025	1904	3	-	-	SYM
fnp-3025	1904	4	8	8	NUM
fnp-3025	1904	5	.	.	NOUN
fnp-3025	1904	6	334	334	NUM
fnp-3025	1904	7	.	.	PUNCT
fnp-3025	1905	1	wyss	wyss	NOUN
fnp-3025	1905	2	-	-	PUNCT
fnp-3025	1905	3	coray	coray	NOUN
fnp-3025	1905	4	,	,	PUNCT
fnp-3025	1905	5	t.	t.	PROPN
fnp-3025	1905	6	,	,	PUNCT
fnp-3025	1905	7	et	et	PROPN
fnp-3025	1905	8	al	al	PROPN
fnp-3025	1905	9	.	.	PROPN
fnp-3025	1905	10	,	,	PUNCT
fnp-3025	1905	11	prominent	prominent	ADJ
fnp-3025	1905	12	neurodegeneration	neurodegeneration	NOUN
fnp-3025	1905	13	and	and	CCONJ
fnp-3025	1905	14	increased	increase	VERB
fnp-3025	1905	15	plaque	plaque	NOUN
fnp-3025	1905	16	formation	formation	NOUN
fnp-3025	1905	17	in	in	ADP
fnp-3025	1905	18	complement	complement	NOUN
fnp-3025	1905	19	-	-	PUNCT
fnp-3025	1905	20	inhibited	inhibit	VERB
fnp-3025	1905	21	alzheimer	alzheimer	NOUN
fnp-3025	1905	22	’s	’s	PART
fnp-3025	1905	23	mice	mouse	NOUN
fnp-3025	1905	24	.	.	PUNCT
fnp-3025	1906	1	proc	proc	PROPN
fnp-3025	1906	2	natl	natl	PROPN
fnp-3025	1906	3	acad	acad	PROPN
fnp-3025	1906	4	sci	sci	PROPN
fnp-3025	1906	5	u	u	PROPN
fnp-3025	1906	6	s	s	PROPN
fnp-3025	1906	7	a	a	PRON
fnp-3025	1906	8	,	,	PUNCT
fnp-3025	1906	9	2002	2002	NUM
fnp-3025	1906	10	.	.	PUNCT
fnp-3025	1907	1	99(16	99(16	NUM
fnp-3025	1907	2	):	):	PUNCT
fnp-3025	1907	3	p.	p.	NOUN
fnp-3025	1907	4	10837	10837	NUM
fnp-3025	1907	5	-	-	SYM
fnp-3025	1907	6	42	42	NUM
fnp-3025	1907	7	.	.	PUNCT
fnp-3025	1908	1	335	335	NUM
fnp-3025	1908	2	.	.	PUNCT
fnp-3025	1909	1	wilcock	wilcock	PROPN
fnp-3025	1909	2	,	,	PUNCT
fnp-3025	1909	3	d.m	d.m	PROPN
fnp-3025	1909	4	.	.	PROPN
fnp-3025	1909	5	,	,	PUNCT
fnp-3025	1909	6	et	et	PROPN
fnp-3025	1909	7	al	al	PROPN
fnp-3025	1909	8	.	.	PROPN
fnp-3025	1909	9	,	,	PUNCT
fnp-3025	1909	10	microglial	microglial	ADJ
fnp-3025	1909	11	activation	activation	NOUN
fnp-3025	1909	12	facilitates	facilitate	VERB
fnp-3025	1909	13	abeta	abeta	ADJ
fnp-3025	1909	14	plaque	plaque	NOUN
fnp-3025	1909	15	removal	removal	NOUN
fnp-3025	1909	16	following	follow	VERB
fnp-3025	1909	17	intracranial	intracranial	ADJ
fnp-3025	1909	18	anti	anti	ADJ
fnp-3025	1909	19	-	-	ADJ
fnp-3025	1909	20	abeta	abeta	ADJ
fnp-3025	1909	21	antibody	antibody	NOUN
fnp-3025	1909	22	administration	administration	NOUN
fnp-3025	1909	23	.	.	PUNCT
fnp-3025	1910	1	neurobiol	neurobiol	PROPN
fnp-3025	1910	2	dis	dis	PROPN
fnp-3025	1910	3	,	,	PUNCT
fnp-3025	1910	4	2004	2004	NUM
fnp-3025	1910	5	.	.	PUNCT
fnp-3025	1911	1	15(1	15(1	NUM
fnp-3025	1911	2	):	):	PUNCT
fnp-3025	1911	3	p.	p.	NOUN
fnp-3025	1911	4	11	11	NUM
fnp-3025	1911	5	-	-	SYM
fnp-3025	1911	6	20	20	NUM
fnp-3025	1911	7	.	.	PUNCT
fnp-3025	1911	8	336	336	NUM
fnp-3025	1911	9	.	.	PUNCT
fnp-3025	1912	1	nicoll	nicoll	PROPN
fnp-3025	1912	2	,	,	PUNCT
fnp-3025	1912	3	j.a.r	j.a.r	PROPN
fnp-3025	1912	4	.	.	PROPN
fnp-3025	1912	5	,	,	PUNCT
fnp-3025	1912	6	et	et	PROPN
fnp-3025	1912	7	al	al	PROPN
fnp-3025	1912	8	.	.	PROPN
fnp-3025	1912	9	,	,	PUNCT
fnp-3025	1912	10	persistent	persistent	ADJ
fnp-3025	1912	11	neuropathological	neuropathological	ADJ
fnp-3025	1912	12	effects	effect	NOUN
fnp-3025	1912	13	14	14	NUM
fnp-3025	1912	14	years	year	NOUN
fnp-3025	1912	15	following	follow	VERB
fnp-3025	1912	16	amyloid	amyloid	NOUN
fnp-3025	1912	17	-	-	PUNCT
fnp-3025	1912	18	beta	beta	NOUN
fnp-3025	1912	19	immunization	immunization	NOUN
fnp-3025	1912	20	in	in	ADP
fnp-3025	1912	21	alzheimer	alzheimer	PROPN
fnp-3025	1912	22	’s	’s	PART
fnp-3025	1912	23	disease	disease	NOUN
fnp-3025	1912	24	.	.	PUNCT
fnp-3025	1913	1	brain	brain	NOUN
fnp-3025	1913	2	,	,	PUNCT
fnp-3025	1913	3	2019	2019	NUM
fnp-3025	1913	4	.	.	PUNCT
fnp-3025	1914	1	142(7	142(7	NUM
fnp-3025	1914	2	):	):	PUNCT
fnp-3025	1914	3	p.	p.	NOUN
fnp-3025	1914	4	2113	2113	NUM
fnp-3025	1914	5	-	-	SYM
fnp-3025	1914	6	2126	2126	NUM
fnp-3025	1914	7	.	.	PUNCT
fnp-3025	1915	1	337	337	NUM
fnp-3025	1915	2	.	.	PUNCT
fnp-3025	1916	1	keren	keren	PROPN
fnp-3025	1916	2	-	-	PUNCT
fnp-3025	1916	3	shaul	shaul	PROPN
fnp-3025	1916	4	,	,	PUNCT
fnp-3025	1916	5	h.	h.	PROPN
fnp-3025	1916	6	,	,	PUNCT
fnp-3025	1916	7	et	et	PROPN
fnp-3025	1916	8	al	al	PROPN
fnp-3025	1916	9	.	.	PROPN
fnp-3025	1916	10	,	,	PUNCT
fnp-3025	1916	11	a	a	DET
fnp-3025	1916	12	unique	unique	ADJ
fnp-3025	1916	13	microglia	microglia	ADJ
fnp-3025	1916	14	type	type	NOUN
fnp-3025	1916	15	associated	associate	VERB
fnp-3025	1916	16	with	with	ADP
fnp-3025	1916	17	restricting	restrict	VERB
fnp-3025	1916	18	development	development	NOUN
fnp-3025	1916	19	of	of	ADP
fnp-3025	1916	20	alzheimer	alzheimer	PROPN
fnp-3025	1916	21	’s	’s	PART
fnp-3025	1916	22	disease	disease	NOUN
fnp-3025	1916	23	.	.	PUNCT
fnp-3025	1917	1	cell	cell	NOUN
fnp-3025	1917	2	,	,	PUNCT
fnp-3025	1917	3	2017	2017	NUM
fnp-3025	1917	4	.	.	PUNCT
fnp-3025	1918	1	169(7	169(7	NUM
fnp-3025	1918	2	):	):	PUNCT
fnp-3025	1918	3	p.	p.	NOUN
fnp-3025	1918	4	1276	1276	NUM
fnp-3025	1918	5	-	-	SYM
fnp-3025	1918	6	1290	1290	NUM
fnp-3025	1918	7	e17	e17	NOUN
fnp-3025	1918	8	.	.	PUNCT
fnp-3025	1919	1	338	338	NUM
fnp-3025	1919	2	.	.	PUNCT
fnp-3025	1920	1	parhizkar	parhizkar	PROPN
fnp-3025	1920	2	,	,	PUNCT
fnp-3025	1920	3	s.	s.	PROPN
fnp-3025	1920	4	,	,	PUNCT
fnp-3025	1920	5	et	et	PROPN
fnp-3025	1920	6	al	al	PROPN
fnp-3025	1920	7	.	.	PROPN
fnp-3025	1920	8	,	,	PUNCT
fnp-3025	1920	9	loss	loss	NOUN
fnp-3025	1920	10	of	of	ADP
fnp-3025	1920	11	trem2	trem2	NOUN
fnp-3025	1920	12	function	function	NOUN
fnp-3025	1920	13	increases	increase	VERB
fnp-3025	1920	14	amyloid	amyloid	NOUN
fnp-3025	1920	15	seeding	seeding	NOUN
fnp-3025	1920	16	but	but	CCONJ
fnp-3025	1920	17	reduces	reduce	VERB
fnp-3025	1920	18	plaque	plaque	NOUN
fnp-3025	1920	19	-	-	PUNCT
fnp-3025	1920	20	associated	associate	VERB
fnp-3025	1920	21	apoe	apoe	NOUN
fnp-3025	1920	22	.	.	PUNCT
fnp-3025	1921	1	nat	nat	PROPN
fnp-3025	1921	2	neurosci	neurosci	PROPN
fnp-3025	1921	3	,	,	PUNCT
fnp-3025	1921	4	2019	2019	NUM
fnp-3025	1921	5	.	.	PUNCT
fnp-3025	1922	1	22(2	22(2	NUM
fnp-3025	1922	2	):	):	PUNCT
fnp-3025	1923	1	p.	p.	NOUN
fnp-3025	1923	2	191	191	NUM
fnp-3025	1923	3	-	-	SYM
fnp-3025	1923	4	204	204	NUM
fnp-3025	1923	5	.	.	PUNCT
fnp-3025	1923	6	339	339	NUM
fnp-3025	1923	7	.	.	PUNCT
fnp-3025	1924	1	leyns	leyn	NOUN
fnp-3025	1924	2	,	,	PUNCT
fnp-3025	1924	3	c.e.g	c.e.g	PROPN
fnp-3025	1924	4	.	.	PROPN
fnp-3025	1924	5	,	,	PUNCT
fnp-3025	1924	6	et	et	PROPN
fnp-3025	1924	7	al	al	PROPN
fnp-3025	1924	8	.	.	PROPN
fnp-3025	1924	9	,	,	PUNCT
fnp-3025	1924	10	trem2	trem2	PROPN
fnp-3025	1924	11	function	function	PROPN
fnp-3025	1924	12	impedes	impede	VERB
fnp-3025	1924	13	tau	tau	PROPN
fnp-3025	1924	14	seeding	seed	VERB
fnp-3025	1924	15	in	in	ADP
fnp-3025	1924	16	neuritic	neuritic	ADJ
fnp-3025	1924	17	plaques	plaque	NOUN
fnp-3025	1924	18	.	.	PUNCT
fnp-3025	1925	1	nat	nat	PROPN
fnp-3025	1925	2	neurosci	neurosci	PROPN
fnp-3025	1925	3	,	,	PUNCT
fnp-3025	1925	4	2019	2019	NUM
fnp-3025	1925	5	.	.	PUNCT
fnp-3025	1926	1	22(8	22(8	NUM
fnp-3025	1926	2	):	):	PUNCT
fnp-3025	1926	3	p.	p.	NOUN
fnp-3025	1926	4	1217	1217	NUM
fnp-3025	1926	5	-	-	SYM
fnp-3025	1926	6	1222	1222	NUM
fnp-3025	1926	7	.	.	PUNCT
fnp-3025	1927	1	340	340	NUM
fnp-3025	1927	2	.	.	PUNCT
fnp-3025	1927	3	frackowiak	frackowiak	PROPN
fnp-3025	1927	4	,	,	PUNCT
fnp-3025	1927	5	j.	j.	PROPN
fnp-3025	1927	6	,	,	PUNCT
fnp-3025	1927	7	et	et	PROPN
fnp-3025	1927	8	al	al	PROPN
fnp-3025	1927	9	.	.	PROPN
fnp-3025	1927	10	,	,	PUNCT
fnp-3025	1927	11	ultrastructure	ultrastructure	NOUN
fnp-3025	1927	12	of	of	ADP
fnp-3025	1927	13	the	the	DET
fnp-3025	1927	14	microglia	microglia	NOUN
fnp-3025	1927	15	that	that	PRON
fnp-3025	1927	16	phagocytose	phagocytose	VERB
fnp-3025	1927	17	amyloid	amyloid	NOUN
fnp-3025	1927	18	and	and	CCONJ
fnp-3025	1927	19	the	the	DET
fnp-3025	1927	20	microglia	microglia	NOUN
fnp-3025	1927	21	that	that	PRON
fnp-3025	1927	22	produce	produce	VERB
fnp-3025	1927	23	beta	beta	NOUN
fnp-3025	1927	24	-	-	PUNCT
fnp-3025	1927	25	amyloid	amyloid	NOUN
fnp-3025	1927	26	fibrils	fibril	NOUN
fnp-3025	1927	27	.	.	PUNCT
fnp-3025	1928	1	acta	acta	PROPN
fnp-3025	1928	2	neuropathol	neuropathol	PROPN
fnp-3025	1928	3	,	,	PUNCT
fnp-3025	1928	4	1992	1992	NUM
fnp-3025	1928	5	.	.	PUNCT
fnp-3025	1929	1	84(3	84(3	NUM
fnp-3025	1929	2	):	):	PUNCT
fnp-3025	1930	1	p.	p.	NOUN
fnp-3025	1930	2	225	225	NUM
fnp-3025	1930	3	-	-	SYM
fnp-3025	1930	4	33	33	NUM
fnp-3025	1930	5	.	.	PUNCT
fnp-3025	1930	6	341	341	NUM
fnp-3025	1930	7	.	.	PUNCT
fnp-3025	1931	1	wisniewski	wisniewski	PROPN
fnp-3025	1931	2	,	,	PUNCT
fnp-3025	1931	3	h.m	h.m	PROPN
fnp-3025	1931	4	.	.	PROPN
fnp-3025	1931	5	,	,	PUNCT
fnp-3025	1931	6	et	et	PROPN
fnp-3025	1931	7	al	al	PROPN
fnp-3025	1931	8	.	.	PROPN
fnp-3025	1931	9	,	,	PUNCT
fnp-3025	1931	10	ultrastructure	ultrastructure	NOUN
fnp-3025	1931	11	of	of	ADP
fnp-3025	1931	12	the	the	DET
fnp-3025	1931	13	cells	cell	NOUN
fnp-3025	1931	14	forming	form	VERB
fnp-3025	1931	15	amyloid	amyloid	NOUN
fnp-3025	1931	16	fibers	fiber	NOUN
fnp-3025	1931	17	in	in	ADP
fnp-3025	1931	18	alzheimer	alzheimer	PROPN
fnp-3025	1931	19	disease	disease	NOUN
fnp-3025	1931	20	and	and	CCONJ
fnp-3025	1931	21	scrapie	scrapie	NOUN
fnp-3025	1931	22	.	.	PUNCT
fnp-3025	1931	23	am	be	AUX
fnp-3025	1931	24	j	j	PROPN
fnp-3025	1931	25	med	med	PROPN
fnp-3025	1931	26	genet	genet	PROPN
fnp-3025	1931	27	suppl	suppl	PROPN
fnp-3025	1931	28	,	,	PUNCT
fnp-3025	1931	29	1990	1990	NUM
fnp-3025	1931	30	.	.	PUNCT
fnp-3025	1932	1	7	7	NUM
fnp-3025	1932	2	:	:	PUNCT
fnp-3025	1932	3	p.	p.	NOUN
fnp-3025	1932	4	287	287	NUM
fnp-3025	1932	5	-	-	SYM
fnp-3025	1932	6	97	97	NUM
fnp-3025	1932	7	.	.	PUNCT
fnp-3025	1932	8	342	342	NUM
fnp-3025	1932	9	.	.	PUNCT
fnp-3025	1933	1	stalder	stalder	PROPN
fnp-3025	1933	2	,	,	PUNCT
fnp-3025	1933	3	m.	m.	NOUN
fnp-3025	1933	4	,	,	PUNCT
fnp-3025	1933	5	et	et	PROPN
fnp-3025	1933	6	al	al	PROPN
fnp-3025	1933	7	.	.	PROPN
fnp-3025	1933	8	,	,	PUNCT
fnp-3025	1933	9	association	association	NOUN
fnp-3025	1933	10	of	of	ADP
fnp-3025	1933	11	microglia	microglia	NOUN
fnp-3025	1933	12	with	with	ADP
fnp-3025	1933	13	amyloid	amyloid	NOUN
fnp-3025	1933	14	plaques	plaque	NOUN
fnp-3025	1933	15	in	in	ADP
fnp-3025	1933	16	brains	brain	NOUN
fnp-3025	1933	17	of	of	ADP
fnp-3025	1933	18	app23	app23	NOUN
fnp-3025	1933	19	transgenic	transgenic	NOUN
fnp-3025	1933	20	mice	mouse	NOUN
fnp-3025	1933	21	.	.	PUNCT
fnp-3025	1933	22	am	be	AUX
fnp-3025	1933	23	j	j	PROPN
fnp-3025	1933	24	pathol	pathol	NOUN
fnp-3025	1933	25	,	,	PUNCT
fnp-3025	1933	26	1999	1999	NUM
fnp-3025	1933	27	.	.	PUNCT
fnp-3025	1934	1	154(6	154(6	NUM
fnp-3025	1934	2	):	):	PUNCT
fnp-3025	1934	3	p.	p.	NOUN
fnp-3025	1934	4	1673	1673	NUM
fnp-3025	1934	5	-	-	SYM
fnp-3025	1934	6	84	84	NUM
fnp-3025	1934	7	.	.	PUNCT
fnp-3025	1935	1	343	343	NUM
fnp-3025	1935	2	.	.	PUNCT
fnp-3025	1936	1	spangenberg	spangenberg	PROPN
fnp-3025	1936	2	,	,	PUNCT
fnp-3025	1936	3	e.	e.	PROPN
fnp-3025	1936	4	,	,	PUNCT
fnp-3025	1936	5	et	et	PROPN
fnp-3025	1936	6	al	al	PROPN
fnp-3025	1936	7	.	.	PROPN
fnp-3025	1936	8	,	,	PUNCT
fnp-3025	1936	9	sustained	sustain	VERB
fnp-3025	1936	10	microglial	microglial	ADJ
fnp-3025	1936	11	depletion	depletion	NOUN
fnp-3025	1936	12	with	with	ADP
fnp-3025	1936	13	csf1r	csf1r	PROPN
fnp-3025	1936	14	inhibitor	inhibitor	NOUN
fnp-3025	1936	15	impairs	impair	VERB
fnp-3025	1936	16	parenchymal	parenchymal	ADJ
fnp-3025	1936	17	plaque	plaque	NOUN
fnp-3025	1936	18	development	development	NOUN
fnp-3025	1936	19	in	in	ADP
fnp-3025	1936	20	an	an	DET
fnp-3025	1936	21	alzheimer	alzheimer	X
fnp-3025	1936	22	’s	’s	PART
fnp-3025	1936	23	disease	disease	NOUN
fnp-3025	1936	24	model	model	NOUN
fnp-3025	1936	25	.	.	PUNCT
fnp-3025	1937	1	nat	nat	PROPN
fnp-3025	1937	2	commun	commun	PROPN
fnp-3025	1937	3	,	,	PUNCT
fnp-3025	1937	4	2019	2019	NUM
fnp-3025	1937	5	.	.	PUNCT
fnp-3025	1938	1	10(1	10(1	NUM
fnp-3025	1938	2	):	):	PUNCT
fnp-3025	1938	3	p.	p.	NOUN
fnp-3025	1938	4	3758	3758	NUM
fnp-3025	1938	5	.	.	PUNCT
fnp-3025	1939	1	344	344	NUM
fnp-3025	1939	2	.	.	PUNCT
fnp-3025	1940	1	hashemiaghdam	hashemiaghdam	PROPN
fnp-3025	1940	2	,	,	PUNCT
fnp-3025	1940	3	a.	a.	NOUN
fnp-3025	1940	4	and	and	CCONJ
fnp-3025	1940	5	m.	m.	NOUN
fnp-3025	1940	6	mroczek	mroczek	NOUN
fnp-3025	1940	7	,	,	PUNCT
fnp-3025	1940	8	microglia	microglia	ADJ
fnp-3025	1940	9	heterogeneity	heterogeneity	NOUN
fnp-3025	1940	10	and	and	CCONJ
fnp-3025	1940	11	neurodegeneration	neurodegeneration	NOUN
fnp-3025	1940	12	:	:	PUNCT
fnp-3025	1940	13	the	the	DET
fnp-3025	1940	14	emerging	emerge	VERB
fnp-3025	1940	15	paradigm	paradigm	NOUN
fnp-3025	1940	16	of	of	ADP
fnp-3025	1940	17	the	the	DET
fnp-3025	1940	18	role	role	NOUN
fnp-3025	1940	19	of	of	ADP
fnp-3025	1940	20	immunity	immunity	NOUN
fnp-3025	1940	21	in	in	ADP
fnp-3025	1940	22	alzheimer	alzheimer	PROPN
fnp-3025	1940	23	’s	’s	PART
fnp-3025	1940	24	disease	disease	NOUN
fnp-3025	1940	25	.	.	PUNCT
fnp-3025	1941	1	j	j	PROPN
fnp-3025	1941	2	neuroimmunol	neuroimmunol	PROPN
fnp-3025	1941	3	,	,	PUNCT
fnp-3025	1941	4	2020	2020	NUM
fnp-3025	1941	5	.	.	PUNCT
fnp-3025	1942	1	341	341	NUM
fnp-3025	1942	2	:	:	PUNCT
fnp-3025	1942	3	p.	p.	NOUN
fnp-3025	1942	4	577185	577185	NUM
fnp-3025	1942	5	.	.	PUNCT
fnp-3025	1943	1	345	345	NUM
fnp-3025	1943	2	.	.	PUNCT
fnp-3025	1944	1	paasila	paasila	PROPN
fnp-3025	1944	2	,	,	PUNCT
fnp-3025	1944	3	p.j	p.j	PROPN
fnp-3025	1944	4	.	.	PROPN
fnp-3025	1944	5	,	,	PUNCT
fnp-3025	1944	6	et	et	PROPN
fnp-3025	1944	7	al	al	PROPN
fnp-3025	1944	8	.	.	PROPN
fnp-3025	1944	9	,	,	PUNCT
fnp-3025	1944	10	clustering	cluster	VERB
fnp-3025	1944	11	of	of	ADP
fnp-3025	1944	12	activated	activate	VERB
fnp-3025	1944	13	microglia	microglia	NOUN
fnp-3025	1944	14	occurs	occur	VERB
fnp-3025	1944	15	before	before	ADP
fnp-3025	1944	16	the	the	DET
fnp-3025	1944	17	formation	formation	NOUN
fnp-3025	1944	18	of	of	ADP
fnp-3025	1944	19	dystrophic	dystrophic	ADJ
fnp-3025	1944	20	neurites	neurite	NOUN
fnp-3025	1944	21	in	in	ADP
fnp-3025	1944	22	the	the	DET
fnp-3025	1944	23	evolution	evolution	NOUN
fnp-3025	1944	24	of	of	ADP
fnp-3025	1944	25	aβ	aβ	DET
fnp-3025	1944	26	plaques	plaque	NOUN
fnp-3025	1944	27	in	in	ADP
fnp-3025	1944	28	alzheimer	alzheimer	PROPN
fnp-3025	1944	29	’s	’s	PART
fnp-3025	1944	30	disease	disease	NOUN
fnp-3025	1944	31	.	.	PUNCT
fnp-3025	1945	1	free	free	ADJ
fnp-3025	1945	2	neuropathology	neuropathology	NOUN
fnp-3025	1945	3	,	,	PUNCT
fnp-3025	1945	4	2020	2020	NUM
fnp-3025	1945	5	.	.	PUNCT
fnp-3025	1946	1	1(20	1(20	NUM
fnp-3025	1946	2	):	):	PUNCT
fnp-3025	1946	3	p.	p.	NOUN
fnp-3025	1946	4	1	1	NUM
fnp-3025	1946	5	-	-	SYM
fnp-3025	1946	6	18	18	NUM
fnp-3025	1946	7	.	.	PUNCT
fnp-3025	1946	8	346	346	NUM
fnp-3025	1946	9	.	.	PUNCT
fnp-3025	1947	1	el	el	PROPN
fnp-3025	1947	2	hajj	hajj	PROPN
fnp-3025	1947	3	,	,	PUNCT
fnp-3025	1947	4	h.	h.	PROPN
fnp-3025	1947	5	,	,	PUNCT
fnp-3025	1947	6	et	et	PROPN
fnp-3025	1947	7	al	al	PROPN
fnp-3025	1947	8	.	.	PROPN
fnp-3025	1947	9	,	,	PUNCT
fnp-3025	1947	10	ultrastructural	ultrastructural	ADJ
fnp-3025	1947	11	evidence	evidence	NOUN
fnp-3025	1947	12	of	of	ADP
fnp-3025	1947	13	microglial	microglial	ADJ
fnp-3025	1947	14	heterogeneity	heterogeneity	NOUN
fnp-3025	1947	15	in	in	ADP
fnp-3025	1947	16	alzheimer	alzheimer	PROPN
fnp-3025	1947	17	’s	’s	PART
fnp-3025	1947	18	disease	disease	NOUN
fnp-3025	1947	19	amyloid	amyloid	PROPN
fnp-3025	1947	20	pathology	pathology	PROPN
fnp-3025	1947	21	.	.	PUNCT
fnp-3025	1948	1	j	j	PROPN
fnp-3025	1948	2	neuroinflammation	neuroinflammation	PROPN
fnp-3025	1948	3	,	,	PUNCT
fnp-3025	1948	4	2019	2019	NUM
fnp-3025	1948	5	.	.	PUNCT
fnp-3025	1949	1	16(1	16(1	NUM
fnp-3025	1949	2	):	):	PUNCT
fnp-3025	1949	3	p.	p.	NOUN
fnp-3025	1949	4	87	87	NUM
fnp-3025	1949	5	.	.	PUNCT
fnp-3025	1950	1	347	347	NUM
fnp-3025	1950	2	.	.	PUNCT
fnp-3025	1951	1	streit	streit	PROPN
fnp-3025	1951	2	,	,	PUNCT
fnp-3025	1951	3	w.j	w.j	PROPN
fnp-3025	1951	4	.	.	PROPN
fnp-3025	1951	5	,	,	PUNCT
fnp-3025	1951	6	h.	h.	PROPN
fnp-3025	1951	7	khoshbouei	khoshbouei	PROPN
fnp-3025	1951	8	,	,	PUNCT
fnp-3025	1951	9	and	and	CCONJ
fnp-3025	1951	10	i.	i.	PROPN
fnp-3025	1951	11	bechmann	bechmann	PROPN
fnp-3025	1951	12	,	,	PUNCT
fnp-3025	1951	13	dystrophic	dystrophic	ADJ
fnp-3025	1951	14	microglia	microglia	NOUN
fnp-3025	1951	15	in	in	ADP
fnp-3025	1951	16	late	late	ADJ
fnp-3025	1951	17	-	-	PUNCT
fnp-3025	1951	18	onset	onset	NOUN
fnp-3025	1951	19	alzheimer	alzheimer	PROPN
fnp-3025	1951	20	’s	’s	PART
fnp-3025	1951	21	disease	disease	NOUN
fnp-3025	1951	22	.	.	PUNCT
fnp-3025	1952	1	glia	glia	PROPN
fnp-3025	1952	2	,	,	PUNCT
fnp-3025	1952	3	2020	2020	NUM
fnp-3025	1952	4	.	.	PUNCT
fnp-3025	1953	1	68(4	68(4	NUM
fnp-3025	1953	2	):	):	PUNCT
fnp-3025	1953	3	p.	p.	NOUN
fnp-3025	1953	4	845	845	NUM
fnp-3025	1953	5	-	-	SYM
fnp-3025	1953	6	854	854	NUM
fnp-3025	1953	7	.	.	NOUN
fnp-3025	1953	8	348	348	NUM
fnp-3025	1953	9	.	.	PUNCT
fnp-3025	1954	1	smith	smith	PROPN
fnp-3025	1954	2	,	,	PUNCT
fnp-3025	1954	3	a.m.	a.m.	NOUN
fnp-3025	1954	4	and	and	CCONJ
fnp-3025	1954	5	m.	m.	NOUN
fnp-3025	1954	6	dragunow	dragunow	PROPN
fnp-3025	1954	7	,	,	PUNCT
fnp-3025	1954	8	the	the	DET
fnp-3025	1954	9	human	human	ADJ
fnp-3025	1954	10	side	side	NOUN
fnp-3025	1954	11	of	of	ADP
fnp-3025	1954	12	microglia	microglia	NOUN
fnp-3025	1954	13	.	.	PUNCT
fnp-3025	1955	1	trends	trend	NOUN
fnp-3025	1955	2	neurosci	neurosci	PROPN
fnp-3025	1955	3	,	,	PUNCT
fnp-3025	1955	4	2014	2014	NUM
fnp-3025	1955	5	.	.	PUNCT
fnp-3025	1956	1	37(3	37(3	NUM
fnp-3025	1956	2	):	):	PUNCT
fnp-3025	1956	3	p.	p.	NOUN
fnp-3025	1956	4	125	125	NUM
fnp-3025	1956	5	-	-	SYM
fnp-3025	1956	6	35	35	NUM
fnp-3025	1956	7	.	.	PUNCT
fnp-3025	1957	1	349	349	NUM
fnp-3025	1957	2	.	.	PUNCT
fnp-3025	1958	1	geirsdottir	geirsdottir	PROPN
fnp-3025	1958	2	,	,	PUNCT
fnp-3025	1958	3	l.	l.	PROPN
fnp-3025	1958	4	,	,	PUNCT
fnp-3025	1958	5	et	et	PROPN
fnp-3025	1958	6	al	al	PROPN
fnp-3025	1958	7	.	.	PROPN
fnp-3025	1958	8	,	,	PUNCT
fnp-3025	1958	9	cross	cross	ADJ
fnp-3025	1958	10	-	-	ADJ
fnp-3025	1958	11	species	species	ADJ
fnp-3025	1958	12	single	single	ADJ
fnp-3025	1958	13	-	-	PUNCT
fnp-3025	1958	14	cell	cell	NOUN
fnp-3025	1958	15	analysis	analysis	NOUN
fnp-3025	1958	16	reveals	reveal	VERB
fnp-3025	1958	17	divergence	divergence	NOUN
fnp-3025	1958	18	of	of	ADP
fnp-3025	1958	19	the	the	DET
fnp-3025	1958	20	primate	primate	ADJ
fnp-3025	1958	21	microglia	microglia	ADJ
fnp-3025	1958	22	program	program	NOUN
fnp-3025	1958	23	.	.	PUNCT
fnp-3025	1959	1	cell	cell	NOUN
fnp-3025	1959	2	,	,	PUNCT
fnp-3025	1959	3	2019	2019	NUM
fnp-3025	1959	4	.	.	PUNCT
fnp-3025	1960	1	179(7	179(7	NUM
fnp-3025	1960	2	):	):	PUNCT
fnp-3025	1960	3	p.	p.	NOUN
fnp-3025	1960	4	1609	1609	NUM
fnp-3025	1960	5	-	-	SYM
fnp-3025	1960	6	1622	1622	NUM
fnp-3025	1960	7	e16	e16	NOUN
fnp-3025	1960	8	.	.	PUNCT
fnp-3025	1961	1	350	350	NUM
fnp-3025	1961	2	.	.	PUNCT
fnp-3025	1962	1	phatnani	phatnani	PROPN
fnp-3025	1962	2	,	,	PUNCT
fnp-3025	1962	3	h.	h.	PROPN
fnp-3025	1962	4	and	and	CCONJ
fnp-3025	1962	5	t.	t.	PROPN
fnp-3025	1962	6	maniatis	maniatis	PROPN
fnp-3025	1962	7	,	,	PUNCT
fnp-3025	1962	8	astrocytes	astrocyte	NOUN
fnp-3025	1962	9	in	in	ADP
fnp-3025	1962	10	neurodegenerative	neurodegenerative	ADJ
fnp-3025	1962	11	disease	disease	NOUN
fnp-3025	1962	12	.	.	PUNCT
fnp-3025	1963	1	cold	cold	ADJ
fnp-3025	1963	2	spring	spring	NOUN
fnp-3025	1963	3	harb	harb	PROPN
fnp-3025	1963	4	perspect	perspect	PROPN
fnp-3025	1963	5	biol	biol	PROPN
fnp-3025	1963	6	,	,	PUNCT
fnp-3025	1963	7	2015	2015	NUM
fnp-3025	1963	8	.	.	PUNCT
fnp-3025	1964	1	7(6	7(6	NUM
fnp-3025	1964	2	):	):	PUNCT
fnp-3025	1964	3	p.	p.	PROPN
fnp-3025	1964	4	a020628	a020628	PROPN
fnp-3025	1964	5	.	.	PUNCT
fnp-3025	1965	1	351	351	NUM
fnp-3025	1965	2	.	.	PUNCT
fnp-3025	1966	1	thal	thal	PROPN
fnp-3025	1966	2	,	,	PUNCT
fnp-3025	1966	3	d.r	d.r	PROPN
fnp-3025	1966	4	.	.	PROPN
fnp-3025	1966	5	,	,	PUNCT
fnp-3025	1966	6	the	the	DET
fnp-3025	1966	7	role	role	NOUN
fnp-3025	1966	8	of	of	ADP
fnp-3025	1966	9	astrocytes	astrocyte	NOUN
fnp-3025	1966	10	in	in	ADP
fnp-3025	1966	11	amyloid	amyloid	NOUN
fnp-3025	1966	12	beta	beta	NOUN
fnp-3025	1966	13	-	-	PUNCT
fnp-3025	1966	14	protein	protein	NOUN
fnp-3025	1966	15	toxicity	toxicity	NOUN
fnp-3025	1966	16	and	and	CCONJ
fnp-3025	1966	17	clearance	clearance	NOUN
fnp-3025	1966	18	.	.	PUNCT
fnp-3025	1967	1	exp	exp	NOUN
fnp-3025	1967	2	neurol	neurol	NOUN
fnp-3025	1967	3	,	,	PUNCT
fnp-3025	1967	4	2012	2012	NUM
fnp-3025	1967	5	.	.	PUNCT
fnp-3025	1968	1	236(1	236(1	NUM
fnp-3025	1968	2	):	):	PUNCT
fnp-3025	1968	3	p.	p.	NOUN
fnp-3025	1968	4	1	1	NUM
fnp-3025	1968	5	-	-	SYM
fnp-3025	1968	6	5	5	NUM
fnp-3025	1968	7	.	.	PUNCT
fnp-3025	1968	8	352	352	NUM
fnp-3025	1968	9	.	.	PUNCT
fnp-3025	1969	1	frost	frost	NOUN
fnp-3025	1969	2	,	,	PUNCT
fnp-3025	1969	3	g.r	g.r	PROPN
fnp-3025	1969	4	.	.	PROPN
fnp-3025	1969	5	and	and	CCONJ
fnp-3025	1969	6	y.m	y.m	PROPN
fnp-3025	1969	7	.	.	PROPN
fnp-3025	1969	8	li	li	PROPN
fnp-3025	1969	9	,	,	PUNCT
fnp-3025	1969	10	the	the	DET
fnp-3025	1969	11	role	role	NOUN
fnp-3025	1969	12	of	of	ADP
fnp-3025	1969	13	astrocytes	astrocyte	NOUN
fnp-3025	1969	14	in	in	ADP
fnp-3025	1969	15	amyloid	amyloid	NOUN
fnp-3025	1969	16	production	production	NOUN
fnp-3025	1969	17	and	and	CCONJ
fnp-3025	1969	18	alzheimer	alzheimer	PROPN
fnp-3025	1969	19	’s	’s	PART
fnp-3025	1969	20	disease	disease	NOUN
fnp-3025	1969	21	.	.	PUNCT
fnp-3025	1970	1	open	open	ADJ
fnp-3025	1970	2	biol	biol	PROPN
fnp-3025	1970	3	,	,	PUNCT
fnp-3025	1970	4	2017	2017	NUM
fnp-3025	1970	5	.	.	PUNCT
fnp-3025	1971	1	7(12	7(12	NUM
fnp-3025	1971	2	):	):	PUNCT
fnp-3025	1971	3	p.	p.	NOUN
fnp-3025	1971	4	170228	170228	NUM
fnp-3025	1971	5	.	.	PUNCT
fnp-3025	1972	1	353	353	NUM
fnp-3025	1972	2	.	.	PUNCT
fnp-3025	1972	3	funato	funato	PROPN
fnp-3025	1972	4	,	,	PUNCT
fnp-3025	1972	5	h.	h.	PROPN
fnp-3025	1972	6	,	,	PUNCT
fnp-3025	1972	7	et	et	PROPN
fnp-3025	1972	8	al	al	PROPN
fnp-3025	1972	9	.	.	PROPN
fnp-3025	1972	10	,	,	PUNCT
fnp-3025	1972	11	astrocytes	astrocyte	NOUN
fnp-3025	1972	12	containing	contain	VERB
fnp-3025	1972	13	amyloid	amyloid	NOUN
fnp-3025	1972	14	beta	beta	NOUN
fnp-3025	1972	15	-	-	PUNCT
fnp-3025	1972	16	protein	protein	NOUN
fnp-3025	1972	17	(	(	PUNCT
fnp-3025	1972	18	abeta)-positive	abeta)-positive	ADJ
fnp-3025	1972	19	granules	granule	NOUN
fnp-3025	1972	20	are	be	AUX
fnp-3025	1972	21	associated	associate	VERB
fnp-3025	1972	22	with	with	ADP
fnp-3025	1972	23	abeta40	abeta40	NOUN
fnp-3025	1972	24	-	-	PUNCT
fnp-3025	1972	25	positive	positive	ADJ
fnp-3025	1972	26	diffuse	diffuse	NOUN
fnp-3025	1972	27	plaques	plaque	NOUN
fnp-3025	1972	28	in	in	ADP
fnp-3025	1972	29	the	the	DET
fnp-3025	1972	30	aged	aged	ADJ
fnp-3025	1972	31	human	human	ADJ
fnp-3025	1972	32	brain	brain	NOUN
fnp-3025	1972	33	.	.	PUNCT
fnp-3025	1973	1	am	be	AUX
fnp-3025	1973	2	j	j	PROPN
fnp-3025	1973	3	pathol	pathol	NOUN
fnp-3025	1973	4	,	,	PUNCT
fnp-3025	1973	5	1998	1998	NUM
fnp-3025	1973	6	.	.	PUNCT
fnp-3025	1974	1	152(4	152(4	NUM
fnp-3025	1974	2	):	):	PUNCT
fnp-3025	1975	1	p.	p.	NOUN
fnp-3025	1975	2	983	983	NUM
fnp-3025	1975	3	-	-	SYM
fnp-3025	1975	4	92	92	NUM
fnp-3025	1975	5	.	.	PUNCT
fnp-3025	1975	6	354	354	NUM
fnp-3025	1975	7	.	.	PUNCT
fnp-3025	1976	1	nagele	nagele	PROPN
fnp-3025	1976	2	,	,	PUNCT
fnp-3025	1976	3	r.g	r.g	PROPN
fnp-3025	1976	4	.	.	PROPN
fnp-3025	1976	5	,	,	PUNCT
fnp-3025	1976	6	et	et	PROPN
fnp-3025	1976	7	al	al	PROPN
fnp-3025	1976	8	.	.	PROPN
fnp-3025	1976	9	,	,	PUNCT
fnp-3025	1976	10	astrocytes	astrocyte	NOUN
fnp-3025	1976	11	accumulate	accumulate	VERB
fnp-3025	1976	12	a	a	DET
fnp-3025	1976	13	beta	beta	NOUN
fnp-3025	1976	14	42	42	NUM
fnp-3025	1976	15	and	and	CCONJ
fnp-3025	1976	16	give	give	VERB
fnp-3025	1976	17	rise	rise	NOUN
fnp-3025	1976	18	to	to	ADP
fnp-3025	1976	19	astrocytic	astrocytic	ADJ
fnp-3025	1976	20	amyloid	amyloid	NOUN
fnp-3025	1976	21	plaques	plaque	NOUN
fnp-3025	1976	22	in	in	ADP
fnp-3025	1976	23	alzheimer	alzheimer	PROPN
fnp-3025	1976	24	disease	disease	NOUN
fnp-3025	1976	25	brains	brain	NOUN
fnp-3025	1976	26	.	.	PUNCT
fnp-3025	1977	1	brain	brain	NOUN
fnp-3025	1977	2	res	re	NOUN
fnp-3025	1977	3	,	,	PUNCT
fnp-3025	1977	4	2003	2003	NUM
fnp-3025	1977	5	.	.	PUNCT
fnp-3025	1978	1	971(2	971(2	NUM
fnp-3025	1978	2	):	):	PUNCT
fnp-3025	1978	3	p.	p.	NOUN
fnp-3025	1978	4	197	197	NUM
fnp-3025	1978	5	-	-	SYM
fnp-3025	1978	6	209	209	NUM
fnp-3025	1978	7	.	.	PUNCT
fnp-3025	1979	1	355	355	NUM
fnp-3025	1979	2	.	.	PUNCT
fnp-3025	1980	1	habib	habib	PROPN
fnp-3025	1980	2	,	,	PUNCT
fnp-3025	1980	3	n.	n.	PROPN
fnp-3025	1980	4	,	,	PUNCT
fnp-3025	1980	5	et	et	PROPN
fnp-3025	1980	6	al	al	PROPN
fnp-3025	1980	7	.	.	PROPN
fnp-3025	1980	8	,	,	PUNCT
fnp-3025	1980	9	disease	disease	NOUN
fnp-3025	1980	10	-	-	PUNCT
fnp-3025	1980	11	associated	associate	VERB
fnp-3025	1980	12	astrocytes	astrocyte	NOUN
fnp-3025	1980	13	in	in	ADP
fnp-3025	1980	14	alzheimer	alzheimer	PROPN
fnp-3025	1980	15	’s	’s	PART
fnp-3025	1980	16	disease	disease	NOUN
fnp-3025	1980	17	and	and	CCONJ
fnp-3025	1980	18	aging	aging	NOUN
fnp-3025	1980	19	.	.	PUNCT
fnp-3025	1981	1	nat	nat	PROPN
fnp-3025	1981	2	neurosci	neurosci	PROPN
fnp-3025	1981	3	,	,	PUNCT
fnp-3025	1981	4	2020	2020	NUM
fnp-3025	1981	5	.	.	PUNCT
fnp-3025	1982	1	23(6	23(6	NUM
fnp-3025	1982	2	):	):	PUNCT
fnp-3025	1983	1	p.	p.	NOUN
fnp-3025	1983	2	701	701	NUM
fnp-3025	1983	3	-	-	SYM
fnp-3025	1983	4	706	706	NUM
fnp-3025	1983	5	.	.	NOUN
fnp-3025	1983	6	356	356	NUM
fnp-3025	1983	7	.	.	PUNCT
fnp-3025	1984	1	matias	matias	PROPN
fnp-3025	1984	2	,	,	PUNCT
fnp-3025	1984	3	i.	i.	PROPN
fnp-3025	1984	4	,	,	PUNCT
fnp-3025	1984	5	j.	j.	PROPN
fnp-3025	1984	6	morgado	morgado	PROPN
fnp-3025	1984	7	,	,	PUNCT
fnp-3025	1984	8	and	and	CCONJ
fnp-3025	1984	9	f.c.a	f.c.a	NOUN
fnp-3025	1984	10	.	.	PUNCT
fnp-3025	1985	1	gomes	gome	NOUN
fnp-3025	1985	2	,	,	PUNCT
fnp-3025	1985	3	astrocyte	astrocyte	NOUN
fnp-3025	1985	4	heterogeneity	heterogeneity	NOUN
fnp-3025	1985	5	:	:	PUNCT
fnp-3025	1985	6	impact	impact	NOUN
fnp-3025	1985	7	to	to	PART
fnp-3025	1985	8	brain	brain	VERB
fnp-3025	1985	9	aging	aging	NOUN
fnp-3025	1985	10	and	and	CCONJ
fnp-3025	1985	11	disease	disease	NOUN
fnp-3025	1985	12	.	.	PUNCT
fnp-3025	1986	1	front	front	ADJ
fnp-3025	1986	2	aging	age	VERB
fnp-3025	1986	3	neurosci	neurosci	NOUN
fnp-3025	1986	4	,	,	PUNCT
fnp-3025	1986	5	2019	2019	NUM
fnp-3025	1986	6	.	.	PUNCT
fnp-3025	1987	1	11	11	NUM
fnp-3025	1987	2	:	:	PUNCT
fnp-3025	1987	3	p.	p.	NOUN
fnp-3025	1987	4	59	59	NUM
fnp-3025	1987	5	.	.	PUNCT
fnp-3025	1987	6	357	357	NUM
fnp-3025	1987	7	.	.	PUNCT
fnp-3025	1988	1	arranz	arranz	PROPN
fnp-3025	1988	2	,	,	PUNCT
fnp-3025	1988	3	a.m.	a.m.	PROPN
fnp-3025	1988	4	and	and	CCONJ
fnp-3025	1988	5	b.	b.	PROPN
fnp-3025	1988	6	de	de	PROPN
fnp-3025	1988	7	strooper	strooper	PROPN
fnp-3025	1988	8	,	,	PUNCT
fnp-3025	1988	9	the	the	DET
fnp-3025	1988	10	role	role	NOUN
fnp-3025	1988	11	of	of	ADP
fnp-3025	1988	12	astroglia	astroglia	PROPN
fnp-3025	1988	13	in	in	ADP
fnp-3025	1988	14	alzheimer	alzheimer	PROPN
fnp-3025	1988	15	’s	’s	PART
fnp-3025	1988	16	disease	disease	NOUN
fnp-3025	1988	17	:	:	PUNCT
fnp-3025	1988	18	pathophysiology	pathophysiology	NOUN
fnp-3025	1988	19	and	and	CCONJ
fnp-3025	1988	20	clinical	clinical	ADJ
fnp-3025	1988	21	implications	implication	NOUN
fnp-3025	1988	22	.	.	PUNCT
fnp-3025	1989	1	lancet	lancet	PROPN
fnp-3025	1989	2	neurol	neurol	PROPN
fnp-3025	1989	3	,	,	PUNCT
fnp-3025	1989	4	2019	2019	NUM
fnp-3025	1989	5	.	.	PUNCT
fnp-3025	1990	1	18(4	18(4	NUM
fnp-3025	1990	2	):	):	PUNCT
fnp-3025	1991	1	p.	p.	NOUN
fnp-3025	1991	2	406	406	NUM
fnp-3025	1991	3	-	-	SYM
fnp-3025	1991	4	414	414	NUM
fnp-3025	1991	5	.	.	PUNCT
fnp-3025	1991	6	358	358	NUM
fnp-3025	1991	7	.	.	PUNCT
fnp-3025	1992	1	holtzman	holtzman	PROPN
fnp-3025	1992	2	,	,	PUNCT
fnp-3025	1992	3	d.	d.	PROPN
fnp-3025	1992	4	and	and	CCONJ
fnp-3025	1992	5	j.	j.	PROPN
fnp-3025	1992	6	ulrich	ulrich	PROPN
fnp-3025	1992	7	,	,	PUNCT
fnp-3025	1992	8	senescent	senescent	ADJ
fnp-3025	1992	9	glia	glia	NOUN
fnp-3025	1992	10	spell	spell	VERB
fnp-3025	1992	11	trouble	trouble	NOUN
fnp-3025	1992	12	in	in	ADP
fnp-3025	1992	13	alzheimer	alzheimer	PROPN
fnp-3025	1992	14	’s	’s	PART
fnp-3025	1992	15	disease	disease	NOUN
fnp-3025	1992	16	.	.	PUNCT
fnp-3025	1993	1	nat	nat	PROPN
fnp-3025	1993	2	neurosci	neurosci	PROPN
fnp-3025	1993	3	,	,	PUNCT
fnp-3025	1993	4	2019	2019	NUM
fnp-3025	1993	5	.	.	PUNCT
fnp-3025	1994	1	22(5	22(5	NOUN
fnp-3025	1994	2	):	):	PUNCT
fnp-3025	1994	3	p.	p.	NOUN
fnp-3025	1994	4	683	683	NUM
fnp-3025	1994	5	-	-	SYM
fnp-3025	1994	6	684	684	NUM
fnp-3025	1994	7	.	.	PUNCT
fnp-3025	1995	1	359	359	NUM
fnp-3025	1995	2	.	.	PUNCT
fnp-3025	1996	1	zhang	zhang	PROPN
fnp-3025	1996	2	,	,	PUNCT
fnp-3025	1996	3	p.	p.	PROPN
fnp-3025	1996	4	,	,	PUNCT
fnp-3025	1996	5	et	et	PROPN
fnp-3025	1996	6	al	al	PROPN
fnp-3025	1996	7	.	.	PROPN
fnp-3025	1996	8	,	,	PUNCT
fnp-3025	1996	9	senolytic	senolytic	ADJ
fnp-3025	1996	10	therapy	therapy	NOUN
fnp-3025	1996	11	alleviates	alleviate	VERB
fnp-3025	1996	12	abeta	abeta	ADV
fnp-3025	1996	13	-	-	PUNCT
fnp-3025	1996	14	associated	associate	VERB
fnp-3025	1996	15	oligodendrocyte	oligodendrocyte	ADJ
fnp-3025	1996	16	progenitor	progenitor	NOUN
fnp-3025	1996	17	cell	cell	NOUN
fnp-3025	1996	18	senescence	senescence	NOUN
fnp-3025	1996	19	and	and	CCONJ
fnp-3025	1996	20	cognitive	cognitive	ADJ
fnp-3025	1996	21	deficits	deficit	NOUN
fnp-3025	1996	22	in	in	ADP
fnp-3025	1996	23	an	an	DET
fnp-3025	1996	24	alzheimer	alzheimer	X
fnp-3025	1996	25	’s	’s	PART
fnp-3025	1996	26	disease	disease	NOUN
fnp-3025	1996	27	model	model	NOUN
fnp-3025	1996	28	.	.	PUNCT
fnp-3025	1997	1	nat	nat	PROPN
fnp-3025	1997	2	neurosci	neurosci	PROPN
fnp-3025	1997	3	,	,	PUNCT
fnp-3025	1997	4	2019	2019	NUM
fnp-3025	1997	5	.	.	PUNCT
fnp-3025	1998	1	22(5	22(5	NOUN
fnp-3025	1998	2	):	):	PUNCT
fnp-3025	1998	3	p.	p.	NOUN
fnp-3025	1998	4	719	719	NUM
fnp-3025	1998	5	-	-	SYM
fnp-3025	1998	6	728	728	NUM
fnp-3025	1998	7	.	.	PUNCT
fnp-3025	1999	1	360	360	NUM
fnp-3025	1999	2	.	.	PUNCT
fnp-3025	2000	1	atwood	atwood	PROPN
fnp-3025	2000	2	,	,	PUNCT
fnp-3025	2000	3	c.s	c.s	PROPN
fnp-3025	2000	4	.	.	PROPN
fnp-3025	2000	5	,	,	PUNCT
fnp-3025	2000	6	et	et	PROPN
fnp-3025	2000	7	al	al	PROPN
fnp-3025	2000	8	.	.	PROPN
fnp-3025	2000	9	,	,	PUNCT
fnp-3025	2000	10	senile	senile	ADJ
fnp-3025	2000	11	plaque	plaque	NOUN
fnp-3025	2000	12	composition	composition	NOUN
fnp-3025	2000	13	and	and	CCONJ
fnp-3025	2000	14	posttranslational	posttranslational	ADJ
fnp-3025	2000	15	modification	modification	NOUN
fnp-3025	2000	16	of	of	ADP
fnp-3025	2000	17	amyloid	amyloid	NOUN
fnp-3025	2000	18	-	-	PUNCT
fnp-3025	2000	19	beta	beta	NOUN
fnp-3025	2000	20	peptide	peptide	NOUN
fnp-3025	2000	21	and	and	CCONJ
fnp-3025	2000	22	associated	associated	ADJ
fnp-3025	2000	23	proteins	protein	NOUN
fnp-3025	2000	24	.	.	PUNCT
fnp-3025	2001	1	peptides	peptide	NOUN
fnp-3025	2001	2	,	,	PUNCT
fnp-3025	2001	3	2002	2002	NUM
fnp-3025	2001	4	.	.	PUNCT
fnp-3025	2002	1	23(7	23(7	NUM
fnp-3025	2002	2	):	):	PUNCT
fnp-3025	2003	1	p.	p.	NOUN
fnp-3025	2003	2	1343	1343	NUM
fnp-3025	2003	3	-	-	SYM
fnp-3025	2003	4	50	50	NUM
fnp-3025	2003	5	.	.	PUNCT
fnp-3025	2003	6	361	361	NUM
fnp-3025	2003	7	.	.	PUNCT
fnp-3025	2004	1	friede	friede	PROPN
fnp-3025	2004	2	,	,	PUNCT
fnp-3025	2004	3	r.l	r.l	PROPN
fnp-3025	2004	4	.	.	PROPN
fnp-3025	2004	5	,	,	PUNCT
fnp-3025	2004	6	enzyme	enzyme	VERB
fnp-3025	2004	7	histochemical	histochemical	ADJ
fnp-3025	2004	8	studies	study	NOUN
fnp-3025	2004	9	of	of	ADP
fnp-3025	2004	10	senile	senile	ADJ
fnp-3025	2004	11	plaques	plaque	NOUN
fnp-3025	2004	12	.	.	PUNCT
fnp-3025	2005	1	journal	journal	NOUN
fnp-3025	2005	2	of	of	ADP
fnp-3025	2005	3	neuropathology	neuropathology	NOUN
fnp-3025	2005	4	and	and	CCONJ
fnp-3025	2005	5	experimental	experimental	ADJ
fnp-3025	2005	6	neurology	neurology	NOUN
fnp-3025	2005	7	,	,	PUNCT
fnp-3025	2005	8	1965	1965	NUM
fnp-3025	2005	9	.	.	PUNCT
fnp-3025	2006	1	24(3	24(3	NUM
fnp-3025	2006	2	):	):	PUNCT
fnp-3025	2006	3	p.	p.	NOUN
fnp-3025	2006	4	477	477	NUM
fnp-3025	2006	5	-	-	SYM
fnp-3025	2006	6	491	491	NUM
fnp-3025	2006	7	.	.	PUNCT
fnp-3025	2007	1	362	362	NUM
fnp-3025	2007	2	.	.	PUNCT
fnp-3025	2008	1	mcgeer	mcgeer	PROPN
fnp-3025	2008	2	,	,	PUNCT
fnp-3025	2008	3	p.l	p.l	PROPN
fnp-3025	2008	4	.	.	PROPN
fnp-3025	2008	5	,	,	PUNCT
fnp-3025	2008	6	et	et	PROPN
fnp-3025	2008	7	al	al	PROPN
fnp-3025	2008	8	.	.	PROPN
fnp-3025	2008	9	,	,	PUNCT
fnp-3025	2008	10	pathological	pathological	ADJ
fnp-3025	2008	11	proteins	protein	NOUN
fnp-3025	2008	12	in	in	ADP
fnp-3025	2008	13	senile	senile	ADJ
fnp-3025	2008	14	plaques	plaque	NOUN
fnp-3025	2008	15	.	.	PUNCT
fnp-3025	2009	1	tohoku	tohoku	PROPN
fnp-3025	2009	2	j	j	PROPN
fnp-3025	2009	3	exp	exp	NUM
fnp-3025	2009	4	med	med	PROPN
fnp-3025	2009	5	,	,	PUNCT
fnp-3025	2009	6	1994	1994	NUM
fnp-3025	2009	7	.	.	PUNCT
fnp-3025	2010	1	174(3	174(3	NUM
fnp-3025	2010	2	):	):	PUNCT
fnp-3025	2010	3	p.	p.	NOUN
fnp-3025	2010	4	269	269	NUM
fnp-3025	2010	5	-	-	SYM
fnp-3025	2010	6	77	77	NUM
fnp-3025	2010	7	.	.	PUNCT
fnp-3025	2011	1	363	363	NUM
fnp-3025	2011	2	.	.	PUNCT
fnp-3025	2011	3	rebeck	rebeck	PROPN
fnp-3025	2011	4	,	,	PUNCT
fnp-3025	2011	5	g.w	g.w	PROPN
fnp-3025	2011	6	.	.	PROPN
fnp-3025	2011	7	,	,	PUNCT
fnp-3025	2011	8	et	et	PROPN
fnp-3025	2011	9	al	al	PROPN
fnp-3025	2011	10	.	.	PROPN
fnp-3025	2011	11	,	,	PUNCT
fnp-3025	2011	12	multiple	multiple	ADJ
fnp-3025	2011	13	,	,	PUNCT
fnp-3025	2011	14	diverse	diverse	ADJ
fnp-3025	2011	15	senile	senile	ADJ
fnp-3025	2011	16	plaque	plaque	NOUN
fnp-3025	2011	17	-	-	PUNCT
fnp-3025	2011	18	associated	associate	VERB
fnp-3025	2011	19	proteins	protein	NOUN
fnp-3025	2011	20	are	be	AUX
fnp-3025	2011	21	ligands	ligand	NOUN
fnp-3025	2011	22	of	of	ADP
fnp-3025	2011	23	an	an	DET
fnp-3025	2011	24	apolipoprotein	apolipoprotein	ADJ
fnp-3025	2011	25	e	e	NOUN
fnp-3025	2011	26	receptor	receptor	NOUN
fnp-3025	2011	27	,	,	PUNCT
fnp-3025	2011	28	the	the	DET
fnp-3025	2011	29	alpha	alpha	ADJ
fnp-3025	2011	30	2	2	NUM
fnp-3025	2011	31	-	-	PUNCT
fnp-3025	2011	32	macroglobulin	macroglobulin	NOUN
fnp-3025	2011	33	receptor	receptor	NOUN
fnp-3025	2011	34	/	/	SYM
fnp-3025	2011	35	low	low	ADJ
fnp-3025	2011	36	-	-	PUNCT
fnp-3025	2011	37	density	density	NOUN
fnp-3025	2011	38	-	-	PUNCT
fnp-3025	2011	39	lipoprotein	lipoprotein	ADJ
fnp-3025	2011	40	receptor	receptor	NOUN
fnp-3025	2011	41	-	-	PUNCT
fnp-3025	2011	42	related	relate	VERB
fnp-3025	2011	43	protein	protein	NOUN
fnp-3025	2011	44	.	.	PUNCT
fnp-3025	2012	1	ann	ann	PROPN
fnp-3025	2012	2	neurol	neurol	PROPN
fnp-3025	2012	3	,	,	PUNCT
fnp-3025	2012	4	1995	1995	NUM
fnp-3025	2012	5	.	.	PUNCT
fnp-3025	2013	1	37(2	37(2	NOUN
fnp-3025	2013	2	):	):	PUNCT
fnp-3025	2013	3	p.	p.	NOUN
fnp-3025	2013	4	211	211	NUM
fnp-3025	2013	5	-	-	SYM
fnp-3025	2013	6	7	7	NUM
fnp-3025	2013	7	.	.	NOUN
fnp-3025	2013	8	364	364	NUM
fnp-3025	2013	9	.	.	PUNCT
fnp-3025	2014	1	stewart	stewart	PROPN
fnp-3025	2014	2	,	,	PUNCT
fnp-3025	2014	3	k.l	k.l	PROPN
fnp-3025	2014	4	.	.	PROPN
fnp-3025	2014	5	and	and	CCONJ
fnp-3025	2014	6	s.e	s.e	PROPN
fnp-3025	2014	7	.	.	PROPN
fnp-3025	2014	8	radford	radford	PROPN
fnp-3025	2014	9	,	,	PUNCT
fnp-3025	2014	10	amyloid	amyloid	NOUN
fnp-3025	2014	11	plaques	plaque	NOUN
fnp-3025	2014	12	beyond	beyond	ADP
fnp-3025	2014	13	abeta	abeta	NOUN
fnp-3025	2014	14	:	:	PUNCT
fnp-3025	2014	15	a	a	DET
fnp-3025	2014	16	survey	survey	NOUN
fnp-3025	2014	17	of	of	ADP
fnp-3025	2014	18	the	the	DET
fnp-3025	2014	19	diverse	diverse	ADJ
fnp-3025	2014	20	modulators	modulator	NOUN
fnp-3025	2014	21	of	of	ADP
fnp-3025	2014	22	amyloid	amyloid	NOUN
fnp-3025	2014	23	aggregation	aggregation	NOUN
fnp-3025	2014	24	.	.	PUNCT
fnp-3025	2015	1	biophys	biophy	NOUN
fnp-3025	2015	2	rev	rev	VERB
fnp-3025	2015	3	,	,	PUNCT
fnp-3025	2015	4	2017	2017	NUM
fnp-3025	2015	5	.	.	PUNCT
fnp-3025	2016	1	9(4	9(4	NOUN
fnp-3025	2016	2	):	):	PUNCT
fnp-3025	2017	1	p.	p.	NOUN
fnp-3025	2017	2	405	405	NUM
fnp-3025	2017	3	-	-	SYM
fnp-3025	2017	4	419	419	NUM
fnp-3025	2017	5	.	.	PUNCT
fnp-3025	2018	1	365	365	NUM
fnp-3025	2018	2	.	.	PUNCT
fnp-3025	2018	3	pepys	pepys	PROPN
fnp-3025	2018	4	,	,	PUNCT
fnp-3025	2018	5	m.b	m.b	PROPN
fnp-3025	2018	6	.	.	PROPN
fnp-3025	2018	7	,	,	PUNCT
fnp-3025	2018	8	et	et	PROPN
fnp-3025	2018	9	al	al	PROPN
fnp-3025	2018	10	.	.	PROPN
fnp-3025	2018	11	,	,	PUNCT
fnp-3025	2018	12	amyloid	amyloid	NOUN
fnp-3025	2018	13	p	p	PROPN
fnp-3025	2018	14	component	component	NOUN
fnp-3025	2018	15	.	.	PUNCT
fnp-3025	2019	1	a	a	DET
fnp-3025	2019	2	critical	critical	ADJ
fnp-3025	2019	3	review	review	NOUN
fnp-3025	2019	4	.	.	PUNCT
fnp-3025	2020	1	amyloid	amyloid	NOUN
fnp-3025	2020	2	,	,	PUNCT
fnp-3025	2020	3	1997	1997	NUM
fnp-3025	2020	4	.	.	PUNCT
fnp-3025	2021	1	4(4	4(4	NUM
fnp-3025	2021	2	):	):	PUNCT
fnp-3025	2022	1	p.	p.	NOUN
fnp-3025	2022	2	274	274	NUM
fnp-3025	2022	3	-	-	SYM
fnp-3025	2022	4	295	295	NUM
fnp-3025	2022	5	.	.	PUNCT
fnp-3025	2023	1	366	366	NUM
fnp-3025	2023	2	.	.	PUNCT
fnp-3025	2024	1	coria	coria	PROPN
fnp-3025	2024	2	,	,	PUNCT
fnp-3025	2024	3	f.	f.	PROPN
fnp-3025	2024	4	,	,	PUNCT
fnp-3025	2024	5	et	et	PROPN
fnp-3025	2024	6	al	al	PROPN
fnp-3025	2024	7	.	.	PROPN
fnp-3025	2024	8	,	,	PUNCT
fnp-3025	2024	9	isolation	isolation	NOUN
fnp-3025	2024	10	and	and	CCONJ
fnp-3025	2024	11	characterization	characterization	NOUN
fnp-3025	2024	12	of	of	ADP
fnp-3025	2024	13	amyloid	amyloid	NOUN
fnp-3025	2024	14	p	p	PROPN
fnp-3025	2024	15	component	component	NOUN
fnp-3025	2024	16	from	from	ADP
fnp-3025	2024	17	alzheimer	alzheimer	PROPN
fnp-3025	2024	18	’s	’s	PART
fnp-3025	2024	19	disease	disease	NOUN
fnp-3025	2024	20	and	and	CCONJ
fnp-3025	2024	21	other	other	ADJ
fnp-3025	2024	22	types	type	NOUN
fnp-3025	2024	23	of	of	ADP
fnp-3025	2024	24	cerebral	cerebral	ADJ
fnp-3025	2024	25	amyloidosis	amyloidosis	NOUN
fnp-3025	2024	26	.	.	PUNCT
fnp-3025	2025	1	lab	lab	NOUN
fnp-3025	2025	2	invest	invest	PROPN
fnp-3025	2025	3	,	,	PUNCT
fnp-3025	2025	4	1988	1988	NUM
fnp-3025	2025	5	.	.	PUNCT
fnp-3025	2026	1	58(4	58(4	NUM
fnp-3025	2026	2	):	):	PUNCT
fnp-3025	2026	3	p.	p.	NOUN
fnp-3025	2026	4	454	454	NUM
fnp-3025	2026	5	-	-	SYM
fnp-3025	2026	6	8	8	NUM
fnp-3025	2026	7	.	.	PUNCT
fnp-3025	2027	1	367	367	NUM
fnp-3025	2027	2	.	.	PUNCT
fnp-3025	2028	1	kalaria	kalaria	PROPN
fnp-3025	2028	2	,	,	PUNCT
fnp-3025	2028	3	r.n	r.n	PROPN
fnp-3025	2028	4	.	.	PROPN
fnp-3025	2028	5	and	and	CCONJ
fnp-3025	2028	6	i.	i.	PROPN
fnp-3025	2028	7	grahovac	grahovac	PROPN
fnp-3025	2028	8	,	,	PUNCT
fnp-3025	2028	9	serum	serum	NOUN
fnp-3025	2028	10	amyloid	amyloid	NOUN
fnp-3025	2028	11	p	p	X
fnp-3025	2029	1	immunoreactivity	immunoreactivity	NOUN
fnp-3025	2029	2	in	in	ADP
fnp-3025	2029	3	hippocampal	hippocampal	ADJ
fnp-3025	2029	4	tangles	tangle	NOUN
fnp-3025	2029	5	,	,	PUNCT
fnp-3025	2029	6	plaques	plaque	NOUN
fnp-3025	2029	7	and	and	CCONJ
fnp-3025	2029	8	vessels	vessel	NOUN
fnp-3025	2029	9	:	:	PUNCT
fnp-3025	2029	10	implications	implication	NOUN
fnp-3025	2029	11	for	for	ADP
fnp-3025	2029	12	leakage	leakage	NOUN
fnp-3025	2029	13	across	across	ADP
fnp-3025	2029	14	the	the	DET
fnp-3025	2029	15	blood	blood	NOUN
fnp-3025	2029	16	-	-	PUNCT
fnp-3025	2029	17	brain	brain	NOUN
fnp-3025	2029	18	barrier	barrier	NOUN
fnp-3025	2029	19	in	in	ADP
fnp-3025	2029	20	alzheimer	alzheimer	PROPN
fnp-3025	2029	21	’s	’s	PART
fnp-3025	2029	22	disease	disease	NOUN
fnp-3025	2029	23	.	.	PUNCT
fnp-3025	2030	1	brain	brain	NOUN
fnp-3025	2030	2	res	re	NOUN
fnp-3025	2030	3	,	,	PUNCT
fnp-3025	2030	4	1990	1990	NUM
fnp-3025	2030	5	.	.	PUNCT
fnp-3025	2031	1	516(2	516(2	NUM
fnp-3025	2031	2	):	):	PUNCT
fnp-3025	2031	3	p.	p.	NOUN
fnp-3025	2031	4	349	349	NUM
fnp-3025	2031	5	-	-	SYM
fnp-3025	2031	6	53	53	NUM
fnp-3025	2031	7	.	.	PUNCT
fnp-3025	2031	8	368	368	NUM
fnp-3025	2031	9	.	.	PUNCT
fnp-3025	2032	1	snow	snow	NOUN
fnp-3025	2032	2	,	,	PUNCT
fnp-3025	2032	3	a.d	a.d	PROPN
fnp-3025	2032	4	.	.	PROPN
fnp-3025	2032	5	,	,	PUNCT
fnp-3025	2032	6	et	et	PROPN
fnp-3025	2032	7	al	al	PROPN
fnp-3025	2032	8	.	.	PROPN
fnp-3025	2032	9	,	,	PUNCT
fnp-3025	2032	10	the	the	DET
fnp-3025	2032	11	presence	presence	NOUN
fnp-3025	2032	12	of	of	ADP
fnp-3025	2032	13	heparan	heparan	ADJ
fnp-3025	2032	14	sulfate	sulfate	NOUN
fnp-3025	2032	15	proteoglycans	proteoglycan	NOUN
fnp-3025	2032	16	in	in	ADP
fnp-3025	2032	17	the	the	DET
fnp-3025	2032	18	neuritic	neuritic	ADJ
fnp-3025	2032	19	plaques	plaque	NOUN
fnp-3025	2032	20	and	and	CCONJ
fnp-3025	2032	21	congophilic	congophilic	ADJ
fnp-3025	2032	22	angiopathy	angiopathy	ADJ
fnp-3025	2032	23	in	in	ADP
fnp-3025	2032	24	alzheimer	alzheimer	PROPN
fnp-3025	2032	25	’s	’s	PART
fnp-3025	2032	26	disease	disease	NOUN
fnp-3025	2032	27	.	.	PUNCT
fnp-3025	2033	1	am	be	AUX
fnp-3025	2033	2	j	j	PROPN
fnp-3025	2033	3	pathol	pathol	NOUN
fnp-3025	2033	4	,	,	PUNCT
fnp-3025	2033	5	1988	1988	NUM
fnp-3025	2033	6	.	.	PUNCT
fnp-3025	2034	1	133(3	133(3	NUM
fnp-3025	2034	2	):	):	PUNCT
fnp-3025	2034	3	p.	p.	NOUN
fnp-3025	2034	4	456	456	NUM
fnp-3025	2034	5	-	-	SYM
fnp-3025	2034	6	63	63	NUM
fnp-3025	2034	7	.	.	PUNCT
fnp-3025	2034	8	369	369	NUM
fnp-3025	2034	9	.	.	PUNCT
fnp-3025	2035	1	snow	snow	PROPN
fnp-3025	2035	2	,	,	PUNCT
fnp-3025	2035	3	a.d	a.d	PROPN
fnp-3025	2035	4	.	.	PROPN
fnp-3025	2035	5	,	,	PUNCT
fnp-3025	2035	6	et	et	PROPN
fnp-3025	2035	7	al	al	PROPN
fnp-3025	2035	8	.	.	PROPN
fnp-3025	2035	9	,	,	PUNCT
fnp-3025	2035	10	early	early	ADJ
fnp-3025	2035	11	accumulation	accumulation	NOUN
fnp-3025	2035	12	of	of	ADP
fnp-3025	2035	13	heparan	heparan	ADJ
fnp-3025	2035	14	sulfate	sulfate	NOUN
fnp-3025	2035	15	in	in	ADP
fnp-3025	2035	16	neurons	neuron	NOUN
fnp-3025	2035	17	and	and	CCONJ
fnp-3025	2035	18	in	in	ADP
fnp-3025	2035	19	the	the	DET
fnp-3025	2035	20	beta	beta	NOUN
fnp-3025	2035	21	-	-	PUNCT
fnp-3025	2035	22	amyloid	amyloid	NOUN
fnp-3025	2035	23	protein	protein	NOUN
fnp-3025	2035	24	-	-	PUNCT
fnp-3025	2035	25	containing	contain	VERB
fnp-3025	2035	26	lesions	lesion	NOUN
fnp-3025	2035	27	of	of	ADP
fnp-3025	2035	28	alzheimer	alzheimer	PROPN
fnp-3025	2035	29	’s	’s	PART
fnp-3025	2035	30	disease	disease	NOUN
fnp-3025	2035	31	and	and	CCONJ
fnp-3025	2035	32	down	down	ADP
fnp-3025	2035	33	’s	’s	PART
fnp-3025	2035	34	syndrome	syndrome	NOUN
fnp-3025	2035	35	.	.	PUNCT
fnp-3025	2036	1	am	be	AUX
fnp-3025	2036	2	j	j	PROPN
fnp-3025	2036	3	pathol	pathol	NOUN
fnp-3025	2036	4	,	,	PUNCT
fnp-3025	2036	5	1990	1990	NUM
fnp-3025	2036	6	.	.	PUNCT
fnp-3025	2037	1	137(5	137(5	NUM
fnp-3025	2037	2	):	):	PUNCT
fnp-3025	2037	3	p.	p.	NOUN
fnp-3025	2037	4	1253	1253	NUM
fnp-3025	2037	5	-	-	SYM
fnp-3025	2037	6	70	70	NUM
fnp-3025	2037	7	.	.	PUNCT
fnp-3025	2038	1	370	370	NUM
fnp-3025	2038	2	.	.	PUNCT
fnp-3025	2039	1	eikelenboom	eikelenboom	NOUN
fnp-3025	2039	2	,	,	PUNCT
fnp-3025	2039	3	p.	p.	PROPN
fnp-3025	2039	4	,	,	PUNCT
fnp-3025	2039	5	et	et	PROPN
fnp-3025	2039	6	al	al	PROPN
fnp-3025	2039	7	.	.	PROPN
fnp-3025	2039	8	,	,	PUNCT
fnp-3025	2039	9	complement	complement	NOUN
fnp-3025	2039	10	activation	activation	NOUN
fnp-3025	2039	11	in	in	ADP
fnp-3025	2039	12	amyloid	amyloid	NOUN
fnp-3025	2039	13	plaques	plaque	NOUN
fnp-3025	2039	14	in	in	ADP
fnp-3025	2039	15	alzheimer	alzheimer	PROPN
fnp-3025	2039	16	’s	’s	PART
fnp-3025	2039	17	dementia	dementia	NOUN
fnp-3025	2039	18	.	.	PUNCT
fnp-3025	2040	1	virchows	virchow	NOUN
fnp-3025	2040	2	arch	arch	VERB
fnp-3025	2040	3	b	b	PROPN
fnp-3025	2040	4	cell	cell	NOUN
fnp-3025	2040	5	pathol	pathol	NOUN
fnp-3025	2040	6	incl	incl	NOUN
fnp-3025	2040	7	mol	mol	ADP
fnp-3025	2040	8	pathol	pathol	NOUN
fnp-3025	2040	9	,	,	PUNCT
fnp-3025	2040	10	1989	1989	NUM
fnp-3025	2040	11	.	.	PUNCT
fnp-3025	2041	1	56(4	56(4	NUM
fnp-3025	2041	2	):	):	PUNCT
fnp-3025	2041	3	p.	p.	NOUN
fnp-3025	2041	4	259	259	NUM
fnp-3025	2041	5	-	-	SYM
fnp-3025	2041	6	62	62	NUM
fnp-3025	2041	7	.	.	PUNCT
fnp-3025	2042	1	371	371	NUM
fnp-3025	2042	2	.	.	X
fnp-3025	2042	3	eikelenboom	eikelenboom	NOUN
fnp-3025	2042	4	,	,	PUNCT
fnp-3025	2042	5	p.	p.	NOUN
fnp-3025	2042	6	and	and	CCONJ
fnp-3025	2042	7	f.c	f.c	PROPN
fnp-3025	2042	8	.	.	PROPN
fnp-3025	2042	9	stam	stam	PROPN
fnp-3025	2042	10	,	,	PUNCT
fnp-3025	2042	11	immunoglobulins	immunoglobulin	NOUN
fnp-3025	2042	12	and	and	CCONJ
fnp-3025	2042	13	complement	complement	NOUN
fnp-3025	2042	14	factors	factor	NOUN
fnp-3025	2042	15	in	in	ADP
fnp-3025	2042	16	senile	senile	ADJ
fnp-3025	2042	17	plaques	plaque	NOUN
fnp-3025	2042	18	.	.	PUNCT
fnp-3025	2043	1	an	an	DET
fnp-3025	2043	2	immunoperoxidase	immunoperoxidase	NOUN
fnp-3025	2043	3	study	study	NOUN
fnp-3025	2043	4	.	.	PUNCT
fnp-3025	2044	1	acta	acta	PROPN
fnp-3025	2044	2	neuropathol	neuropathol	PROPN
fnp-3025	2044	3	,	,	PUNCT
fnp-3025	2044	4	1982	1982	NUM
fnp-3025	2044	5	.	.	PUNCT
fnp-3025	2045	1	57(2	57(2	NUM
fnp-3025	2045	2	-	-	SYM
fnp-3025	2045	3	3	3	NUM
fnp-3025	2045	4	):	):	PUNCT
fnp-3025	2045	5	p.	p.	NOUN
fnp-3025	2045	6	239	239	NUM
fnp-3025	2045	7	-	-	SYM
fnp-3025	2045	8	42	42	NUM
fnp-3025	2045	9	.	.	PUNCT
fnp-3025	2046	1	372	372	NUM
fnp-3025	2046	2	.	.	PUNCT
fnp-3025	2046	3	ishii	ishii	PROPN
fnp-3025	2046	4	,	,	PUNCT
fnp-3025	2046	5	t.	t.	PROPN
fnp-3025	2046	6	and	and	CCONJ
fnp-3025	2046	7	s.	s.	PROPN
fnp-3025	2046	8	haga	haga	PROPN
fnp-3025	2046	9	,	,	PUNCT
fnp-3025	2046	10	immuno	immuno	ADJ
fnp-3025	2046	11	-	-	PUNCT
fnp-3025	2046	12	electron	electron	NOUN
fnp-3025	2046	13	-	-	PUNCT
fnp-3025	2046	14	microscopic	microscopic	NOUN
fnp-3025	2046	15	localization	localization	NOUN
fnp-3025	2046	16	of	of	ADP
fnp-3025	2046	17	complements	complement	NOUN
fnp-3025	2046	18	in	in	ADP
fnp-3025	2046	19	amyloid	amyloid	NOUN
fnp-3025	2046	20	fibrils	fibril	NOUN
fnp-3025	2046	21	of	of	ADP
fnp-3025	2046	22	senile	senile	ADJ
fnp-3025	2046	23	plaques	plaque	NOUN
fnp-3025	2046	24	.	.	PUNCT
fnp-3025	2047	1	acta	acta	PROPN
fnp-3025	2047	2	neuropathol	neuropathol	PROPN
fnp-3025	2047	3	,	,	PUNCT
fnp-3025	2047	4	1984	1984	NUM
fnp-3025	2047	5	.	.	PUNCT
fnp-3025	2048	1	63(4	63(4	NOUN
fnp-3025	2048	2	):	):	PUNCT
fnp-3025	2048	3	p.	p.	NOUN
fnp-3025	2048	4	296	296	NUM
fnp-3025	2048	5	-	-	SYM
fnp-3025	2048	6	300	300	NUM
fnp-3025	2048	7	.	.	PUNCT
fnp-3025	2049	1	373	373	NUM
fnp-3025	2049	2	.	.	PUNCT
fnp-3025	2050	1	rogers	rogers	PROPN
fnp-3025	2050	2	,	,	PUNCT
fnp-3025	2050	3	j.	j.	PROPN
fnp-3025	2050	4	,	,	PUNCT
fnp-3025	2050	5	et	et	PROPN
fnp-3025	2050	6	al	al	PROPN
fnp-3025	2050	7	.	.	PROPN
fnp-3025	2050	8	,	,	PUNCT
fnp-3025	2050	9	complement	complement	NOUN
fnp-3025	2050	10	activation	activation	NOUN
fnp-3025	2050	11	by	by	ADP
fnp-3025	2050	12	beta	beta	NOUN
fnp-3025	2050	13	-	-	PUNCT
fnp-3025	2050	14	amyloid	amyloid	NOUN
fnp-3025	2050	15	in	in	ADP
fnp-3025	2050	16	alzheimer	alzheimer	PROPN
fnp-3025	2050	17	disease	disease	PROPN
fnp-3025	2050	18	.	.	PUNCT
fnp-3025	2051	1	proc	proc	PROPN
fnp-3025	2051	2	natl	natl	PROPN
fnp-3025	2051	3	acad	acad	PROPN
fnp-3025	2051	4	sci	sci	PROPN
fnp-3025	2051	5	u	u	PROPN
fnp-3025	2051	6	s	s	PROPN
fnp-3025	2051	7	a	a	DET
fnp-3025	2051	8	,	,	PUNCT
fnp-3025	2051	9	1992	1992	NUM
fnp-3025	2051	10	.	.	PUNCT
fnp-3025	2052	1	89(21	89(21	NUM
fnp-3025	2052	2	):	):	PUNCT
fnp-3025	2052	3	p.	p.	NOUN
fnp-3025	2052	4	10016	10016	NUM
fnp-3025	2052	5	-	-	SYM
fnp-3025	2052	6	20	20	NUM
fnp-3025	2052	7	.	.	PUNCT
fnp-3025	2053	1	374	374	NUM
fnp-3025	2053	2	.	.	PUNCT
fnp-3025	2054	1	namba	namba	PROPN
fnp-3025	2054	2	,	,	PUNCT
fnp-3025	2054	3	y.	y.	PROPN
fnp-3025	2054	4	,	,	PUNCT
fnp-3025	2054	5	et	et	PROPN
fnp-3025	2054	6	al	al	PROPN
fnp-3025	2054	7	.	.	PROPN
fnp-3025	2054	8	,	,	PUNCT
fnp-3025	2054	9	apolipoprotein	apolipoprotein	VERB
fnp-3025	2054	10	e	e	PROPN
fnp-3025	2054	11	immunoreactivity	immunoreactivity	NOUN
fnp-3025	2054	12	in	in	ADP
fnp-3025	2054	13	cerebral	cerebral	ADJ
fnp-3025	2054	14	amyloid	amyloid	NOUN
fnp-3025	2054	15	deposits	deposit	NOUN
fnp-3025	2054	16	and	and	CCONJ
fnp-3025	2054	17	neurofibrillary	neurofibrillary	ADJ
fnp-3025	2054	18	tangles	tangle	NOUN
fnp-3025	2054	19	in	in	ADP
fnp-3025	2054	20	alzheimer	alzheimer	PROPN
fnp-3025	2054	21	’s	’s	PART
fnp-3025	2054	22	disease	disease	NOUN
fnp-3025	2054	23	and	and	CCONJ
fnp-3025	2054	24	kuru	kuru	NOUN
fnp-3025	2054	25	plaque	plaque	NOUN
fnp-3025	2054	26	amyloid	amyloid	NOUN
fnp-3025	2054	27	in	in	ADP
fnp-3025	2054	28	creutzfeldt	creutzfeldt	ADJ
fnp-3025	2054	29	-	-	ADJ
fnp-3025	2054	30	jakob	jakob	ADJ
fnp-3025	2054	31	disease	disease	NOUN
fnp-3025	2054	32	.	.	PUNCT
fnp-3025	2055	1	brain	brain	NOUN
fnp-3025	2055	2	res	re	NOUN
fnp-3025	2055	3	,	,	PUNCT
fnp-3025	2055	4	1991	1991	NUM
fnp-3025	2055	5	.	.	PUNCT
fnp-3025	2056	1	541(1	541(1	NUM
fnp-3025	2056	2	):	):	PUNCT
fnp-3025	2056	3	p.	p.	NOUN
fnp-3025	2056	4	163	163	NUM
fnp-3025	2056	5	-	-	SYM
fnp-3025	2056	6	6	6	NUM
fnp-3025	2056	7	.	.	NOUN
fnp-3025	2056	8	375	375	NUM
fnp-3025	2056	9	.	.	PUNCT
fnp-3025	2057	1	nishiyama	nishiyama	NOUN
fnp-3025	2057	2	,	,	PUNCT
fnp-3025	2057	3	e.	e.	PROPN
fnp-3025	2057	4	,	,	PUNCT
fnp-3025	2057	5	et	et	PROPN
fnp-3025	2057	6	al	al	PROPN
fnp-3025	2057	7	.	.	PROPN
fnp-3025	2057	8	,	,	PUNCT
fnp-3025	2057	9	distribution	distribution	NOUN
fnp-3025	2057	10	of	of	ADP
fnp-3025	2057	11	apolipoprotein	apolipoprotein	ADJ
fnp-3025	2057	12	e	e	NOUN
fnp-3025	2057	13	in	in	ADP
fnp-3025	2057	14	senile	senile	ADJ
fnp-3025	2057	15	plaques	plaque	NOUN
fnp-3025	2057	16	in	in	ADP
fnp-3025	2057	17	brains	brain	NOUN
fnp-3025	2057	18	with	with	ADP
fnp-3025	2057	19	alzheimer	alzheimer	PROPN
fnp-3025	2057	20	’s	’s	PART
fnp-3025	2057	21	disease	disease	NOUN
fnp-3025	2057	22	:	:	PUNCT
fnp-3025	2057	23	investigation	investigation	NOUN
fnp-3025	2057	24	with	with	ADP
fnp-3025	2057	25	the	the	DET
fnp-3025	2057	26	confocal	confocal	ADJ
fnp-3025	2057	27	laser	laser	NOUN
fnp-3025	2057	28	scan	scan	PROPN
fnp-3025	2057	29	microscope	microscope	NOUN
fnp-3025	2057	30	.	.	PUNCT
fnp-3025	2058	1	brain	brain	NOUN
fnp-3025	2058	2	res	re	NOUN
fnp-3025	2058	3	,	,	PUNCT
fnp-3025	2058	4	1997	1997	NUM
fnp-3025	2058	5	.	.	PUNCT
fnp-3025	2059	1	750(1	750(1	NUM
fnp-3025	2059	2	-	-	SYM
fnp-3025	2059	3	2	2	NUM
fnp-3025	2059	4	):	):	PUNCT
fnp-3025	2059	5	p.	p.	NOUN
fnp-3025	2059	6	20	20	NUM
fnp-3025	2059	7	-	-	SYM
fnp-3025	2059	8	4	4	NUM
fnp-3025	2059	9	.	.	NUM
fnp-3025	2059	10	376	376	NUM
fnp-3025	2059	11	.	.	PUNCT
fnp-3025	2060	1	abraham	abraham	PROPN
fnp-3025	2060	2	,	,	PUNCT
fnp-3025	2060	3	c.r	c.r	PROPN
fnp-3025	2060	4	.	.	PROPN
fnp-3025	2060	5	,	,	PUNCT
fnp-3025	2060	6	d.j	d.j	PROPN
fnp-3025	2060	7	.	.	PROPN
fnp-3025	2060	8	selkoe	selkoe	PROPN
fnp-3025	2060	9	,	,	PUNCT
fnp-3025	2060	10	and	and	CCONJ
fnp-3025	2060	11	h.	h.	PROPN
fnp-3025	2060	12	potter	potter	PROPN
fnp-3025	2060	13	,	,	PUNCT
fnp-3025	2060	14	immunochemical	immunochemical	ADJ
fnp-3025	2060	15	identification	identification	NOUN
fnp-3025	2060	16	of	of	ADP
fnp-3025	2060	17	the	the	DET
fnp-3025	2060	18	serine	serine	NOUN
fnp-3025	2060	19	protease	protease	NOUN
fnp-3025	2060	20	inhibitor	inhibitor	NOUN
fnp-3025	2060	21	alpha	alpha	NOUN
fnp-3025	2060	22	1	1	NUM
fnp-3025	2060	23	-	-	PUNCT
fnp-3025	2060	24	antichymotrypsin	antichymotrypsin	NOUN
fnp-3025	2060	25	in	in	ADP
fnp-3025	2060	26	the	the	DET
fnp-3025	2060	27	brain	brain	NOUN
fnp-3025	2060	28	amyloid	amyloid	NOUN
fnp-3025	2060	29	deposits	deposit	NOUN
fnp-3025	2060	30	of	of	ADP
fnp-3025	2060	31	alzheimer	alzheimer	PROPN
fnp-3025	2060	32	’s	’s	PART
fnp-3025	2060	33	disease	disease	NOUN
fnp-3025	2060	34	.	.	PUNCT
fnp-3025	2061	1	cell	cell	NOUN
fnp-3025	2061	2	,	,	PUNCT
fnp-3025	2061	3	1988	1988	NUM
fnp-3025	2061	4	.	.	PUNCT
fnp-3025	2062	1	52(4	52(4	NUM
fnp-3025	2062	2	):	):	PUNCT
fnp-3025	2063	1	p.	p.	NOUN
fnp-3025	2063	2	487	487	NUM
fnp-3025	2063	3	-	-	SYM
fnp-3025	2063	4	501	501	NUM
fnp-3025	2063	5	.	.	PUNCT
fnp-3025	2063	6	377	377	NUM
fnp-3025	2063	7	.	.	PUNCT
fnp-3025	2064	1	sasaki	sasaki	PROPN
fnp-3025	2064	2	,	,	PUNCT
fnp-3025	2064	3	n.	n.	PROPN
fnp-3025	2064	4	,	,	PUNCT
fnp-3025	2064	5	et	et	PROPN
fnp-3025	2064	6	al	al	PROPN
fnp-3025	2064	7	.	.	PROPN
fnp-3025	2064	8	,	,	PUNCT
fnp-3025	2064	9	advanced	advanced	ADJ
fnp-3025	2064	10	glycation	glycation	NOUN
fnp-3025	2064	11	end	end	NOUN
fnp-3025	2064	12	products	product	NOUN
fnp-3025	2064	13	in	in	ADP
fnp-3025	2064	14	alzheimer	alzheimer	PROPN
fnp-3025	2064	15	’s	’s	PART
fnp-3025	2064	16	disease	disease	NOUN
fnp-3025	2064	17	and	and	CCONJ
fnp-3025	2064	18	other	other	ADJ
fnp-3025	2064	19	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2064	20	diseases	disease	NOUN
fnp-3025	2064	21	.	.	PUNCT
fnp-3025	2065	1	am	be	AUX
fnp-3025	2065	2	j	j	PROPN
fnp-3025	2065	3	pathol	pathol	NOUN
fnp-3025	2065	4	,	,	PUNCT
fnp-3025	2065	5	1998	1998	NUM
fnp-3025	2065	6	.	.	PUNCT
fnp-3025	2066	1	153(4	153(4	NUM
fnp-3025	2066	2	):	):	PUNCT
fnp-3025	2067	1	p.	p.	NOUN
fnp-3025	2067	2	1149	1149	NUM
fnp-3025	2067	3	-	-	SYM
fnp-3025	2067	4	55	55	NUM
fnp-3025	2067	5	.	.	PUNCT
fnp-3025	2067	6	378	378	NUM
fnp-3025	2067	7	.	.	PUNCT
fnp-3025	2068	1	smith	smith	PROPN
fnp-3025	2068	2	,	,	PUNCT
fnp-3025	2068	3	m.a	m.a	PROPN
fnp-3025	2068	4	.	.	PROPN
fnp-3025	2068	5	,	,	PUNCT
fnp-3025	2068	6	et	et	PROPN
fnp-3025	2068	7	al	al	PROPN
fnp-3025	2068	8	.	.	PROPN
fnp-3025	2068	9	,	,	PUNCT
fnp-3025	2068	10	advanced	advanced	ADJ
fnp-3025	2068	11	maillard	maillard	NOUN
fnp-3025	2068	12	reaction	reaction	NOUN
fnp-3025	2068	13	end	end	NOUN
fnp-3025	2068	14	products	product	NOUN
fnp-3025	2068	15	are	be	AUX
fnp-3025	2068	16	associated	associate	VERB
fnp-3025	2068	17	with	with	ADP
fnp-3025	2068	18	alzheimer	alzheimer	PROPN
fnp-3025	2068	19	disease	disease	PROPN
fnp-3025	2068	20	pathology	pathology	PROPN
fnp-3025	2068	21	.	.	PUNCT
fnp-3025	2069	1	proc	proc	PROPN
fnp-3025	2069	2	natl	natl	PROPN
fnp-3025	2069	3	acad	acad	PROPN
fnp-3025	2069	4	sci	sci	PROPN
fnp-3025	2069	5	u	u	PROPN
fnp-3025	2069	6	s	s	PROPN
fnp-3025	2069	7	a	a	PRON
fnp-3025	2069	8	,	,	PUNCT
fnp-3025	2069	9	1994	1994	NUM
fnp-3025	2069	10	.	.	PUNCT
fnp-3025	2070	1	91(12	91(12	NUM
fnp-3025	2070	2	):	):	PUNCT
fnp-3025	2070	3	p.	p.	NOUN
fnp-3025	2070	4	5710	5710	NUM
fnp-3025	2070	5	-	-	SYM
fnp-3025	2070	6	4	4	NUM
fnp-3025	2070	7	.	.	NUM
fnp-3025	2070	8	379	379	NUM
fnp-3025	2070	9	.	.	PUNCT
fnp-3025	2071	1	roy	roy	PROPN
fnp-3025	2071	2	,	,	PUNCT
fnp-3025	2071	3	e.r	e.r	PROPN
fnp-3025	2071	4	.	.	PROPN
fnp-3025	2071	5	,	,	PUNCT
fnp-3025	2071	6	et	et	PROPN
fnp-3025	2071	7	al	al	PROPN
fnp-3025	2071	8	.	.	PROPN
fnp-3025	2071	9	,	,	PUNCT
fnp-3025	2071	10	type	type	VERB
fnp-3025	2071	11	i	i	PRON
fnp-3025	2071	12	interferon	interferon	ADJ
fnp-3025	2071	13	response	response	NOUN
fnp-3025	2071	14	drives	drive	VERB
fnp-3025	2071	15	neuroinflammation	neuroinflammation	NOUN
fnp-3025	2071	16	and	and	CCONJ
fnp-3025	2071	17	synapse	synapse	VERB
fnp-3025	2071	18	loss	loss	NOUN
fnp-3025	2071	19	in	in	ADP
fnp-3025	2071	20	alzheimer	alzheimer	PROPN
fnp-3025	2071	21	disease	disease	PROPN
fnp-3025	2071	22	.	.	PUNCT
fnp-3025	2072	1	j	j	PROPN
fnp-3025	2072	2	clin	clin	PROPN
fnp-3025	2072	3	invest	invest	PROPN
fnp-3025	2072	4	,	,	PUNCT
fnp-3025	2072	5	2020	2020	NUM
fnp-3025	2072	6	.	.	PUNCT
fnp-3025	2073	1	130(4	130(4	NUM
fnp-3025	2073	2	):	):	PUNCT
fnp-3025	2073	3	p.	p.	NOUN
fnp-3025	2073	4	1912	1912	NUM
fnp-3025	2073	5	-	-	SYM
fnp-3025	2073	6	1930	1930	NUM
fnp-3025	2073	7	.	.	PUNCT
fnp-3025	2074	1	380	380	NUM
fnp-3025	2074	2	.	.	X
fnp-3025	2074	3	bastrup	bastrup	NOUN
fnp-3025	2074	4	,	,	PUNCT
fnp-3025	2074	5	j.	j.	PROPN
fnp-3025	2074	6	,	,	PUNCT
fnp-3025	2074	7	et	et	PROPN
fnp-3025	2074	8	al	al	PROPN
fnp-3025	2074	9	.	.	PROPN
fnp-3025	2074	10	,	,	PUNCT
fnp-3025	2074	11	proteomic	proteomic	NOUN
fnp-3025	2074	12	and	and	CCONJ
fnp-3025	2074	13	unbiased	unbiased	ADJ
fnp-3025	2074	14	post	post	ADJ
fnp-3025	2074	15	-	-	ADJ
fnp-3025	2074	16	translational	translational	ADJ
fnp-3025	2074	17	modification	modification	NOUN
fnp-3025	2074	18	profiling	profiling	NOUN
fnp-3025	2074	19	of	of	ADP
fnp-3025	2074	20	amyloid	amyloid	NOUN
fnp-3025	2074	21	plaques	plaque	NOUN
fnp-3025	2074	22	and	and	CCONJ
fnp-3025	2074	23	surrounding	surround	VERB
fnp-3025	2074	24	tissue	tissue	NOUN
fnp-3025	2074	25	in	in	ADP
fnp-3025	2074	26	a	a	DET
fnp-3025	2074	27	transgenic	transgenic	NOUN
fnp-3025	2074	28	mouse	mouse	NOUN
fnp-3025	2074	29	model	model	NOUN
fnp-3025	2074	30	of	of	ADP
fnp-3025	2074	31	alzheimer	alzheimer	PROPN
fnp-3025	2074	32	’s	’s	PART
fnp-3025	2074	33	disease	disease	NOUN
fnp-3025	2074	34	.	.	PUNCT
fnp-3025	2075	1	j	j	PROPN
fnp-3025	2075	2	alzheimers	alzheimers	PROPN
fnp-3025	2075	3	dis	dis	PROPN
fnp-3025	2075	4	,	,	PUNCT
fnp-3025	2075	5	2020	2020	NUM
fnp-3025	2075	6	.	.	PUNCT
fnp-3025	2076	1	73(1	73(1	NUM
fnp-3025	2076	2	):	):	PUNCT
fnp-3025	2077	1	p.	p.	NOUN
fnp-3025	2077	2	393	393	NUM
fnp-3025	2077	3	-	-	SYM
fnp-3025	2077	4	411	411	NUM
fnp-3025	2077	5	.	.	PUNCT
fnp-3025	2077	6	381	381	NUM
fnp-3025	2077	7	.	.	PUNCT
fnp-3025	2078	1	liao	liao	PROPN
fnp-3025	2078	2	,	,	PUNCT
fnp-3025	2078	3	l.	l.	PROPN
fnp-3025	2078	4	,	,	PUNCT
fnp-3025	2078	5	et	et	PROPN
fnp-3025	2078	6	al	al	PROPN
fnp-3025	2078	7	.	.	PROPN
fnp-3025	2078	8	,	,	PUNCT
fnp-3025	2078	9	proteomic	proteomic	ADJ
fnp-3025	2078	10	characterization	characterization	NOUN
fnp-3025	2078	11	of	of	ADP
fnp-3025	2078	12	postmortem	postmortem	NOUN
fnp-3025	2078	13	amyloid	amyloid	NOUN
fnp-3025	2078	14	plaques	plaque	NOUN
fnp-3025	2078	15	isolated	isolate	VERB
fnp-3025	2078	16	by	by	ADP
fnp-3025	2078	17	laser	laser	NOUN
fnp-3025	2078	18	capture	capture	NOUN
fnp-3025	2078	19	microdissection	microdissection	NOUN
fnp-3025	2078	20	.	.	PUNCT
fnp-3025	2079	1	j	j	PROPN
fnp-3025	2079	2	biol	biol	PROPN
fnp-3025	2079	3	chem	chem	NOUN
fnp-3025	2079	4	,	,	PUNCT
fnp-3025	2079	5	2004	2004	NUM
fnp-3025	2079	6	.	.	PUNCT
fnp-3025	2080	1	279(35	279(35	NUM
fnp-3025	2080	2	):	):	PUNCT
fnp-3025	2080	3	p.	p.	NOUN
fnp-3025	2080	4	37061	37061	NUM
fnp-3025	2080	5	-	-	SYM
fnp-3025	2080	6	8	8	NUM
fnp-3025	2080	7	.	.	PUNCT
fnp-3025	2081	1	382	382	NUM
fnp-3025	2081	2	.	.	PUNCT
fnp-3025	2082	1	lutz	lutz	PROPN
fnp-3025	2082	2	,	,	PUNCT
fnp-3025	2082	3	b.m	b.m	PROPN
fnp-3025	2082	4	.	.	PROPN
fnp-3025	2082	5	and	and	CCONJ
fnp-3025	2082	6	j.	j.	PROPN
fnp-3025	2082	7	peng	peng	PROPN
fnp-3025	2082	8	,	,	PUNCT
fnp-3025	2082	9	deep	deep	ADJ
fnp-3025	2082	10	profiling	profiling	NOUN
fnp-3025	2082	11	of	of	ADP
fnp-3025	2082	12	the	the	DET
fnp-3025	2082	13	aggregated	aggregate	VERB
fnp-3025	2082	14	proteome	proteome	NOUN
fnp-3025	2082	15	in	in	ADP
fnp-3025	2082	16	alzheimer	alzheimer	PROPN
fnp-3025	2082	17	’s	’s	PART
fnp-3025	2082	18	disease	disease	NOUN
fnp-3025	2082	19	:	:	PUNCT
fnp-3025	2082	20	from	from	ADP
fnp-3025	2082	21	pathology	pathology	NOUN
fnp-3025	2082	22	to	to	ADP
fnp-3025	2082	23	disease	disease	NOUN
fnp-3025	2082	24	mechanisms	mechanism	NOUN
fnp-3025	2082	25	.	.	PUNCT
fnp-3025	2083	1	proteomes	proteome	NOUN
fnp-3025	2083	2	,	,	PUNCT
fnp-3025	2083	3	2018	2018	NUM
fnp-3025	2083	4	.	.	PUNCT
fnp-3025	2084	1	6(4	6(4	NOUN
fnp-3025	2084	2	):	):	PUNCT
fnp-3025	2084	3	p.	p.	NOUN
fnp-3025	2084	4	46	46	NUM
fnp-3025	2084	5	.	.	PUNCT
fnp-3025	2085	1	383	383	NUM
fnp-3025	2085	2	.	.	PUNCT
fnp-3025	2086	1	xiong	xiong	PROPN
fnp-3025	2086	2	,	,	PUNCT
fnp-3025	2086	3	f.	f.	PROPN
fnp-3025	2086	4	,	,	PUNCT
fnp-3025	2086	5	w.	w.	PROPN
fnp-3025	2086	6	ge	ge	PROPN
fnp-3025	2086	7	,	,	PUNCT
fnp-3025	2086	8	and	and	CCONJ
fnp-3025	2086	9	c.	c.	PROPN
fnp-3025	2086	10	ma	ma	PROPN
fnp-3025	2086	11	,	,	PUNCT
fnp-3025	2086	12	quantitative	quantitative	ADJ
fnp-3025	2086	13	proteomics	proteomic	NOUN
fnp-3025	2086	14	reveals	reveal	VERB
fnp-3025	2086	15	distinct	distinct	ADJ
fnp-3025	2086	16	composition	composition	NOUN
fnp-3025	2086	17	of	of	ADP
fnp-3025	2086	18	amyloid	amyloid	NOUN
fnp-3025	2086	19	plaques	plaque	NOUN
fnp-3025	2086	20	in	in	ADP
fnp-3025	2086	21	alzheimer	alzheimer	PROPN
fnp-3025	2086	22	’s	’s	PART
fnp-3025	2086	23	disease	disease	NOUN
fnp-3025	2086	24	.	.	PUNCT
fnp-3025	2087	1	alzheimers	alzheimers	PROPN
fnp-3025	2087	2	dement	dement	PROPN
fnp-3025	2087	3	,	,	PUNCT
fnp-3025	2087	4	2019	2019	NUM
fnp-3025	2087	5	.	.	PUNCT
fnp-3025	2088	1	15(3	15(3	NUM
fnp-3025	2088	2	):	):	PUNCT
fnp-3025	2088	3	p.	p.	NOUN
fnp-3025	2088	4	429	429	NUM
fnp-3025	2088	5	-	-	SYM
fnp-3025	2088	6	440	440	NUM
fnp-3025	2088	7	.	.	PUNCT
fnp-3025	2089	1	384	384	NUM
fnp-3025	2089	2	.	.	PUNCT
fnp-3025	2090	1	drummond	drummond	PROPN
fnp-3025	2090	2	,	,	PUNCT
fnp-3025	2090	3	e.	e.	PROPN
fnp-3025	2090	4	,	,	PUNCT
fnp-3025	2090	5	et	et	PROPN
fnp-3025	2090	6	al	al	PROPN
fnp-3025	2090	7	.	.	PROPN
fnp-3025	2090	8	,	,	PUNCT
fnp-3025	2090	9	proteomic	proteomic	ADJ
fnp-3025	2090	10	differences	difference	NOUN
fnp-3025	2090	11	in	in	ADP
fnp-3025	2090	12	amyloid	amyloid	NOUN
fnp-3025	2090	13	plaques	plaque	NOUN
fnp-3025	2090	14	in	in	ADP
fnp-3025	2090	15	rapidly	rapidly	ADV
fnp-3025	2090	16	progressive	progressive	ADJ
fnp-3025	2090	17	and	and	CCONJ
fnp-3025	2090	18	sporadic	sporadic	PROPN
fnp-3025	2090	19	alzheimer	alzheimer	PROPN
fnp-3025	2090	20	’s	’s	PART
fnp-3025	2090	21	disease	disease	NOUN
fnp-3025	2090	22	.	.	PUNCT
fnp-3025	2091	1	acta	acta	PROPN
fnp-3025	2091	2	neuropathol	neuropathol	PROPN
fnp-3025	2091	3	,	,	PUNCT
fnp-3025	2091	4	2017	2017	NUM
fnp-3025	2091	5	.	.	PUNCT
fnp-3025	2092	1	133(6	133(6	NUM
fnp-3025	2092	2	):	):	PUNCT
fnp-3025	2093	1	p.	p.	NOUN
fnp-3025	2093	2	933	933	NUM
fnp-3025	2093	3	-	-	SYM
fnp-3025	2093	4	954	954	NUM
fnp-3025	2093	5	.	.	NOUN
fnp-3025	2093	6	385	385	NUM
fnp-3025	2093	7	.	.	PUNCT
fnp-3025	2094	1	nijholt	nijholt	PROPN
fnp-3025	2094	2	,	,	PUNCT
fnp-3025	2094	3	d.a	d.a	PROPN
fnp-3025	2094	4	.	.	PROPN
fnp-3025	2094	5	,	,	PUNCT
fnp-3025	2094	6	c.	c.	PROPN
fnp-3025	2094	7	stingl	stingl	PROPN
fnp-3025	2094	8	,	,	PUNCT
fnp-3025	2094	9	and	and	CCONJ
fnp-3025	2094	10	t.m	t.m	PROPN
fnp-3025	2094	11	.	.	PROPN
fnp-3025	2094	12	luider	luider	PROPN
fnp-3025	2094	13	,	,	PUNCT
fnp-3025	2094	14	laser	laser	NOUN
fnp-3025	2094	15	capture	capture	NOUN
fnp-3025	2094	16	microdissection	microdissection	NOUN
fnp-3025	2094	17	of	of	ADP
fnp-3025	2094	18	fluorescently	fluorescently	ADV
fnp-3025	2094	19	labeled	label	VERB
fnp-3025	2094	20	amyloid	amyloid	NOUN
fnp-3025	2094	21	plaques	plaque	NOUN
fnp-3025	2094	22	from	from	ADP
fnp-3025	2094	23	alzheimer	alzheimer	PROPN
fnp-3025	2094	24	’s	’s	PART
fnp-3025	2094	25	disease	disease	NOUN
fnp-3025	2094	26	brain	brain	NOUN
fnp-3025	2094	27	tissue	tissue	NOUN
fnp-3025	2094	28	for	for	ADP
fnp-3025	2094	29	mass	mass	ADJ
fnp-3025	2094	30	spectrometric	spectrometric	ADJ
fnp-3025	2094	31	analysis	analysis	NOUN
fnp-3025	2094	32	.	.	PUNCT
fnp-3025	2095	1	methods	method	NOUN
fnp-3025	2095	2	mol	mol	ADP
fnp-3025	2095	3	biol	biol	PROPN
fnp-3025	2095	4	,	,	PUNCT
fnp-3025	2095	5	2015	2015	NUM
fnp-3025	2095	6	.	.	PUNCT
fnp-3025	2096	1	1243	1243	NUM
fnp-3025	2096	2	:	:	PUNCT
fnp-3025	2097	1	p.	p.	NOUN
fnp-3025	2097	2	165	165	NUM
fnp-3025	2097	3	-	-	SYM
fnp-3025	2097	4	73	73	NUM
fnp-3025	2097	5	.	.	PUNCT
fnp-3025	2097	6	386	386	NUM
fnp-3025	2097	7	.	.	PUNCT
fnp-3025	2098	1	rijal	rijal	PROPN
fnp-3025	2098	2	upadhaya	upadhaya	PROPN
fnp-3025	2098	3	,	,	PUNCT
fnp-3025	2098	4	a.	a.	PROPN
fnp-3025	2098	5	,	,	PUNCT
fnp-3025	2098	6	et	et	PROPN
fnp-3025	2098	7	al	al	PROPN
fnp-3025	2098	8	.	.	PROPN
fnp-3025	2098	9	,	,	PUNCT
fnp-3025	2098	10	biochemical	biochemical	ADJ
fnp-3025	2098	11	stages	stage	NOUN
fnp-3025	2098	12	of	of	ADP
fnp-3025	2098	13	amyloid	amyloid	NOUN
fnp-3025	2098	14	-	-	PUNCT
fnp-3025	2098	15	beta	beta	NOUN
fnp-3025	2098	16	peptide	peptide	NOUN
fnp-3025	2098	17	aggregation	aggregation	NOUN
fnp-3025	2098	18	and	and	CCONJ
fnp-3025	2098	19	accumulation	accumulation	NOUN
fnp-3025	2098	20	in	in	ADP
fnp-3025	2098	21	the	the	DET
fnp-3025	2098	22	human	human	ADJ
fnp-3025	2098	23	brain	brain	NOUN
fnp-3025	2098	24	and	and	CCONJ
fnp-3025	2098	25	their	their	PRON
fnp-3025	2098	26	association	association	NOUN
fnp-3025	2098	27	with	with	ADP
fnp-3025	2098	28	symptomatic	symptomatic	ADJ
fnp-3025	2098	29	and	and	CCONJ
fnp-3025	2098	30	pathologically	pathologically	ADV
fnp-3025	2098	31	preclinical	preclinical	ADJ
fnp-3025	2098	32	alzheimer	alzheimer	PROPN
fnp-3025	2098	33	’s	’s	PART
fnp-3025	2098	34	disease	disease	NOUN
fnp-3025	2098	35	.	.	PUNCT
fnp-3025	2099	1	brain	brain	NOUN
fnp-3025	2099	2	,	,	PUNCT
fnp-3025	2099	3	2014	2014	NUM
fnp-3025	2099	4	.	.	PUNCT
fnp-3025	2100	1	137(pt	137(pt	NUM
fnp-3025	2101	1	3	3	NUM
fnp-3025	2101	2	):	):	PUNCT
fnp-3025	2101	3	p.	p.	NOUN
fnp-3025	2101	4	887	887	NUM
fnp-3025	2101	5	-	-	SYM
fnp-3025	2101	6	903	903	NUM
fnp-3025	2101	7	.	.	PUNCT
fnp-3025	2102	1	387	387	NUM
fnp-3025	2102	2	.	.	PUNCT
fnp-3025	2102	3	hu	hu	PROPN
fnp-3025	2102	4	,	,	PUNCT
fnp-3025	2102	5	z.w	z.w	PROPN
fnp-3025	2102	6	.	.	PROPN
fnp-3025	2102	7	,	,	PUNCT
fnp-3025	2102	8	et	et	PROPN
fnp-3025	2102	9	al	al	PROPN
fnp-3025	2102	10	.	.	PROPN
fnp-3025	2102	11	,	,	PUNCT
fnp-3025	2102	12	molecular	molecular	ADJ
fnp-3025	2102	13	structure	structure	NOUN
fnp-3025	2102	14	of	of	ADP
fnp-3025	2102	15	an	an	DET
fnp-3025	2102	16	n	n	ADV
fnp-3025	2102	17	-	-	PUNCT
fnp-3025	2102	18	terminal	terminal	ADJ
fnp-3025	2102	19	phosphorylated	phosphorylate	VERB
fnp-3025	2102	20	beta	beta	NOUN
fnp-3025	2102	21	-	-	PUNCT
fnp-3025	2102	22	amyloid	amyloid	NOUN
fnp-3025	2102	23	fibril	fibril	NOUN
fnp-3025	2102	24	.	.	PUNCT
fnp-3025	2103	1	proc	proc	PROPN
fnp-3025	2103	2	natl	natl	PROPN
fnp-3025	2103	3	acad	acad	PROPN
fnp-3025	2103	4	sci	sci	PROPN
fnp-3025	2103	5	u	u	PROPN
fnp-3025	2103	6	s	s	PROPN
fnp-3025	2103	7	a	a	PRON
fnp-3025	2103	8	,	,	PUNCT
fnp-3025	2103	9	2019	2019	NUM
fnp-3025	2103	10	.	.	PUNCT
fnp-3025	2104	1	116(23	116(23	NOUN
fnp-3025	2104	2	):	):	PUNCT
fnp-3025	2104	3	p.	p.	NOUN
fnp-3025	2104	4	11253	11253	NUM
fnp-3025	2104	5	-	-	SYM
fnp-3025	2104	6	11258	11258	NUM
fnp-3025	2104	7	.	.	PUNCT
fnp-3025	2105	1	388	388	NUM
fnp-3025	2105	2	.	.	PUNCT
fnp-3025	2105	3	michno	michno	PROPN
fnp-3025	2105	4	,	,	PUNCT
fnp-3025	2105	5	w.	w.	PROPN
fnp-3025	2105	6	,	,	PUNCT
fnp-3025	2105	7	et	et	PROPN
fnp-3025	2105	8	al	al	PROPN
fnp-3025	2105	9	.	.	PROPN
fnp-3025	2105	10	,	,	PUNCT
fnp-3025	2105	11	pyroglutamation	pyroglutamation	NOUN
fnp-3025	2105	12	of	of	ADP
fnp-3025	2105	13	amyloid	amyloid	NOUN
fnp-3025	2105	14	-	-	PUNCT
fnp-3025	2105	15	betax-42	betax-42	PROPN
fnp-3025	2105	16	(	(	PUNCT
fnp-3025	2105	17	abetax-42	abetax-42	PROPN
fnp-3025	2105	18	)	)	PUNCT
fnp-3025	2105	19	followed	follow	VERB
fnp-3025	2105	20	by	by	ADP
fnp-3025	2105	21	abeta1	abeta1	PROPN
fnp-3025	2105	22	-	-	PUNCT
fnp-3025	2105	23	40	40	NUM
fnp-3025	2105	24	deposition	deposition	NOUN
fnp-3025	2105	25	underlies	underlie	VERB
fnp-3025	2105	26	plaque	plaque	NOUN
fnp-3025	2105	27	polymorphism	polymorphism	NOUN
fnp-3025	2105	28	in	in	ADP
fnp-3025	2105	29	progressing	progress	VERB
fnp-3025	2105	30	alzheimer	alzheimer	PROPN
fnp-3025	2105	31	’s	’s	PART
fnp-3025	2105	32	disease	disease	NOUN
fnp-3025	2105	33	pathology	pathology	PROPN
fnp-3025	2105	34	.	.	PUNCT
fnp-3025	2106	1	j	j	PROPN
fnp-3025	2106	2	biol	biol	PROPN
fnp-3025	2106	3	chem	chem	NOUN
fnp-3025	2106	4	,	,	PUNCT
fnp-3025	2106	5	2019	2019	NUM
fnp-3025	2106	6	.	.	PUNCT
fnp-3025	2107	1	294(17	294(17	NUM
fnp-3025	2107	2	):	):	PUNCT
fnp-3025	2107	3	p.	p.	NOUN
fnp-3025	2107	4	6719	6719	NUM
fnp-3025	2107	5	-	-	SYM
fnp-3025	2107	6	6732	6732	NUM
fnp-3025	2107	7	.	.	PUNCT
fnp-3025	2108	1	389	389	NUM
fnp-3025	2108	2	.	.	PUNCT
fnp-3025	2109	1	roher	roher	PROPN
fnp-3025	2109	2	,	,	PUNCT
fnp-3025	2109	3	a.e	a.e	PROPN
fnp-3025	2109	4	.	.	PROPN
fnp-3025	2109	5	,	,	PUNCT
fnp-3025	2109	6	et	et	PROPN
fnp-3025	2109	7	al	al	PROPN
fnp-3025	2109	8	.	.	PROPN
fnp-3025	2109	9	,	,	PUNCT
fnp-3025	2109	10	structural	structural	ADJ
fnp-3025	2109	11	alterations	alteration	NOUN
fnp-3025	2109	12	in	in	ADP
fnp-3025	2109	13	the	the	DET
fnp-3025	2109	14	peptide	peptide	ADJ
fnp-3025	2109	15	backbone	backbone	NOUN
fnp-3025	2109	16	of	of	ADP
fnp-3025	2109	17	beta	beta	NOUN
fnp-3025	2109	18	-	-	PUNCT
fnp-3025	2109	19	amyloid	amyloid	NOUN
fnp-3025	2109	20	core	core	NOUN
fnp-3025	2109	21	protein	protein	NOUN
fnp-3025	2109	22	may	may	AUX
fnp-3025	2109	23	account	account	VERB
fnp-3025	2109	24	for	for	ADP
fnp-3025	2109	25	its	its	PRON
fnp-3025	2109	26	deposition	deposition	NOUN
fnp-3025	2109	27	and	and	CCONJ
fnp-3025	2109	28	stability	stability	NOUN
fnp-3025	2109	29	in	in	ADP
fnp-3025	2109	30	alzheimer	alzheimer	PROPN
fnp-3025	2109	31	’s	’s	PART
fnp-3025	2109	32	disease	disease	NOUN
fnp-3025	2109	33	.	.	PUNCT
fnp-3025	2110	1	j	j	PROPN
fnp-3025	2110	2	biol	biol	PROPN
fnp-3025	2110	3	chem	chem	NOUN
fnp-3025	2110	4	,	,	PUNCT
fnp-3025	2110	5	1993	1993	NUM
fnp-3025	2110	6	.	.	PUNCT
fnp-3025	2111	1	268(5	268(5	NUM
fnp-3025	2111	2	):	):	PUNCT
fnp-3025	2111	3	p.	p.	NOUN
fnp-3025	2111	4	3072	3072	NUM
fnp-3025	2111	5	-	-	SYM
fnp-3025	2111	6	83	83	NUM
fnp-3025	2111	7	.	.	PUNCT
fnp-3025	2112	1	390	390	NUM
fnp-3025	2112	2	.	.	PUNCT
fnp-3025	2113	1	wildburger	wildburger	NOUN
fnp-3025	2113	2	,	,	PUNCT
fnp-3025	2113	3	n.c	n.c	PROPN
fnp-3025	2113	4	.	.	PROPN
fnp-3025	2113	5	,	,	PUNCT
fnp-3025	2113	6	et	et	PROPN
fnp-3025	2113	7	al	al	PROPN
fnp-3025	2113	8	.	.	PROPN
fnp-3025	2113	9	,	,	PUNCT
fnp-3025	2113	10	diversity	diversity	NOUN
fnp-3025	2113	11	of	of	ADP
fnp-3025	2113	12	amyloid	amyloid	NOUN
fnp-3025	2113	13	-	-	PUNCT
fnp-3025	2113	14	beta	beta	NOUN
fnp-3025	2113	15	proteoforms	proteoform	NOUN
fnp-3025	2113	16	in	in	ADP
fnp-3025	2113	17	the	the	DET
fnp-3025	2113	18	alzheimer	alzheimer	PROPN
fnp-3025	2113	19	’s	’s	PART
fnp-3025	2113	20	disease	disease	NOUN
fnp-3025	2113	21	brain	brain	NOUN
fnp-3025	2113	22	.	.	PUNCT
fnp-3025	2114	1	sci	sci	PROPN
fnp-3025	2114	2	rep	rep	PROPN
fnp-3025	2114	3	,	,	PUNCT
fnp-3025	2114	4	2017	2017	NUM
fnp-3025	2114	5	.	.	PUNCT
fnp-3025	2115	1	7(1	7(1	NUM
fnp-3025	2115	2	):	):	PUNCT
fnp-3025	2115	3	p.	p.	NOUN
fnp-3025	2115	4	9520	9520	NUM
fnp-3025	2115	5	.	.	PUNCT
fnp-3025	2116	1	391	391	NUM
fnp-3025	2116	2	.	.	PUNCT
fnp-3025	2117	1	wisniewski	wisniewski	PROPN
fnp-3025	2117	2	,	,	PUNCT
fnp-3025	2117	3	t.	t.	PROPN
fnp-3025	2117	4	,	,	PUNCT
fnp-3025	2117	5	j.	j.	PROPN
fnp-3025	2117	6	ghiso	ghiso	PROPN
fnp-3025	2117	7	,	,	PUNCT
fnp-3025	2117	8	and	and	CCONJ
fnp-3025	2117	9	b.	b.	PROPN
fnp-3025	2117	10	frangione	frangione	PROPN
fnp-3025	2117	11	,	,	PUNCT
fnp-3025	2117	12	biology	biology	NOUN
fnp-3025	2117	13	of	of	ADP
fnp-3025	2117	14	a	a	DET
fnp-3025	2117	15	beta	beta	ADJ
fnp-3025	2117	16	amyloid	amyloid	NOUN
fnp-3025	2117	17	in	in	ADP
fnp-3025	2117	18	alzheimer	alzheimer	PROPN
fnp-3025	2117	19	’s	’s	PART
fnp-3025	2117	20	disease	disease	NOUN
fnp-3025	2117	21	.	.	PUNCT
fnp-3025	2118	1	neurobiol	neurobiol	PROPN
fnp-3025	2118	2	dis	dis	PROPN
fnp-3025	2118	3	,	,	PUNCT
fnp-3025	2118	4	1997	1997	NUM
fnp-3025	2118	5	.	.	PUNCT
fnp-3025	2119	1	4(5	4(5	NUM
fnp-3025	2119	2	):	):	PUNCT
fnp-3025	2120	1	p.	p.	NOUN
fnp-3025	2120	2	313	313	NUM
fnp-3025	2120	3	-	-	SYM
fnp-3025	2120	4	28	28	NUM
fnp-3025	2120	5	.	.	PUNCT
fnp-3025	2120	6	392	392	NUM
fnp-3025	2120	7	.	.	PUNCT
fnp-3025	2121	1	miklossy	miklossy	PROPN
fnp-3025	2121	2	,	,	PUNCT
fnp-3025	2121	3	j.	j.	PROPN
fnp-3025	2121	4	,	,	PUNCT
fnp-3025	2121	5	bacterial	bacterial	ADJ
fnp-3025	2121	6	amyloid	amyloid	NOUN
fnp-3025	2121	7	and	and	CCONJ
fnp-3025	2121	8	dna	dna	NOUN
fnp-3025	2121	9	are	be	AUX
fnp-3025	2121	10	important	important	ADJ
fnp-3025	2121	11	constituents	constituent	NOUN
fnp-3025	2121	12	of	of	ADP
fnp-3025	2121	13	senile	senile	ADJ
fnp-3025	2121	14	plaques	plaque	NOUN
fnp-3025	2121	15	:	:	PUNCT
fnp-3025	2121	16	further	further	ADJ
fnp-3025	2121	17	evidence	evidence	NOUN
fnp-3025	2121	18	of	of	ADP
fnp-3025	2121	19	the	the	DET
fnp-3025	2121	20	spirochetal	spirochetal	ADJ
fnp-3025	2121	21	and	and	CCONJ
fnp-3025	2121	22	biofilm	biofilm	NOUN
fnp-3025	2121	23	nature	nature	NOUN
fnp-3025	2121	24	of	of	ADP
fnp-3025	2121	25	senile	senile	ADJ
fnp-3025	2121	26	plaques	plaque	NOUN
fnp-3025	2121	27	.	.	PUNCT
fnp-3025	2122	1	j	j	PROPN
fnp-3025	2122	2	alzheimers	alzheimers	PROPN
fnp-3025	2122	3	dis	dis	PROPN
fnp-3025	2122	4	,	,	PUNCT
fnp-3025	2122	5	2016	2016	NUM
fnp-3025	2122	6	.	.	PUNCT
fnp-3025	2123	1	53(4	53(4	NUM
fnp-3025	2123	2	):	):	PUNCT
fnp-3025	2123	3	p.	p.	NOUN
fnp-3025	2123	4	1459	1459	NUM
fnp-3025	2123	5	-	-	SYM
fnp-3025	2123	6	73	73	NUM
fnp-3025	2123	7	.	.	PUNCT
fnp-3025	2124	1	393	393	NUM
fnp-3025	2124	2	.	.	PUNCT
fnp-3025	2125	1	itzhaki	itzhaki	ADJ
fnp-3025	2125	2	,	,	PUNCT
fnp-3025	2125	3	r.f	r.f	PROPN
fnp-3025	2125	4	.	.	PROPN
fnp-3025	2125	5	,	,	PUNCT
fnp-3025	2125	6	et	et	PROPN
fnp-3025	2125	7	al	al	PROPN
fnp-3025	2125	8	.	.	PROPN
fnp-3025	2125	9	,	,	PUNCT
fnp-3025	2125	10	do	do	AUX
fnp-3025	2125	11	infections	infection	NOUN
fnp-3025	2125	12	have	have	VERB
fnp-3025	2125	13	a	a	DET
fnp-3025	2125	14	role	role	NOUN
fnp-3025	2125	15	in	in	ADP
fnp-3025	2125	16	the	the	DET
fnp-3025	2125	17	pathogenesis	pathogenesis	NOUN
fnp-3025	2125	18	of	of	ADP
fnp-3025	2125	19	alzheimer	alzheimer	PROPN
fnp-3025	2125	20	disease	disease	PROPN
fnp-3025	2125	21	?	?	PUNCT
fnp-3025	2126	1	nat	nat	PROPN
fnp-3025	2126	2	rev	rev	PROPN
fnp-3025	2126	3	neurol	neurol	PROPN
fnp-3025	2126	4	,	,	PUNCT
fnp-3025	2126	5	2020	2020	NUM
fnp-3025	2126	6	.	.	PUNCT
fnp-3025	2127	1	16(4	16(4	NUM
fnp-3025	2127	2	):	):	PUNCT
fnp-3025	2128	1	p.	p.	NOUN
fnp-3025	2128	2	193	193	NUM
fnp-3025	2128	3	-	-	SYM
fnp-3025	2128	4	197	197	NUM
fnp-3025	2128	5	.	.	PUNCT
fnp-3025	2128	6	394	394	NUM
fnp-3025	2128	7	.	.	PUNCT
fnp-3025	2129	1	itzhaki	itzhaki	ADJ
fnp-3025	2129	2	,	,	PUNCT
fnp-3025	2129	3	r.f	r.f	PROPN
fnp-3025	2129	4	.	.	PROPN
fnp-3025	2129	5	,	,	PUNCT
fnp-3025	2129	6	et	et	PROPN
fnp-3025	2129	7	al	al	PROPN
fnp-3025	2129	8	.	.	PROPN
fnp-3025	2129	9	,	,	PUNCT
fnp-3025	2129	10	microbes	microbe	NOUN
fnp-3025	2129	11	and	and	CCONJ
fnp-3025	2129	12	alzheimer	alzheimer	PROPN
fnp-3025	2129	13	’s	’s	PART
fnp-3025	2129	14	disease	disease	NOUN
fnp-3025	2129	15	.	.	PUNCT
fnp-3025	2130	1	j	j	PROPN
fnp-3025	2130	2	alzheimers	alzheimers	PROPN
fnp-3025	2130	3	dis	dis	PROPN
fnp-3025	2130	4	,	,	PUNCT
fnp-3025	2130	5	2016	2016	NUM
fnp-3025	2130	6	.	.	PUNCT
fnp-3025	2131	1	51(4	51(4	NUM
fnp-3025	2131	2	):	):	PUNCT
fnp-3025	2131	3	p.	p.	NOUN
fnp-3025	2131	4	979	979	NUM
fnp-3025	2131	5	-	-	SYM
fnp-3025	2131	6	84	84	NUM
fnp-3025	2131	7	.	.	PUNCT
fnp-3025	2132	1	395	395	NUM
fnp-3025	2132	2	.	.	PUNCT
fnp-3025	2132	3	moir	moir	PROPN
fnp-3025	2132	4	,	,	PUNCT
fnp-3025	2132	5	r.d	r.d	PROPN
fnp-3025	2132	6	.	.	PROPN
fnp-3025	2132	7	,	,	PUNCT
fnp-3025	2132	8	r.	r.	PROPN
fnp-3025	2132	9	lathe	lathe	PROPN
fnp-3025	2132	10	,	,	PUNCT
fnp-3025	2132	11	and	and	CCONJ
fnp-3025	2132	12	r.e	r.e	PROPN
fnp-3025	2132	13	.	.	PROPN
fnp-3025	2132	14	tanzi	tanzi	PROPN
fnp-3025	2132	15	,	,	PUNCT
fnp-3025	2132	16	the	the	DET
fnp-3025	2132	17	antimicrobial	antimicrobial	ADJ
fnp-3025	2132	18	protection	protection	NOUN
fnp-3025	2132	19	hypothesis	hypothesis	NOUN
fnp-3025	2132	20	of	of	ADP
fnp-3025	2132	21	alzheimer	alzheimer	PROPN
fnp-3025	2132	22	’s	’s	PART
fnp-3025	2132	23	disease	disease	NOUN
fnp-3025	2132	24	.	.	PUNCT
fnp-3025	2133	1	alzheimers	alzheimers	PROPN
fnp-3025	2133	2	dement	dement	PROPN
fnp-3025	2133	3	,	,	PUNCT
fnp-3025	2133	4	2018	2018	NUM
fnp-3025	2133	5	.	.	PUNCT
fnp-3025	2134	1	14(12	14(12	NUM
fnp-3025	2134	2	):	):	PUNCT
fnp-3025	2134	3	p.	p.	NOUN
fnp-3025	2134	4	1602	1602	NUM
fnp-3025	2134	5	-	-	SYM
fnp-3025	2134	6	1614	1614	NUM
fnp-3025	2134	7	.	.	PUNCT
fnp-3025	2135	1	396	396	NUM
fnp-3025	2135	2	.	.	PUNCT
fnp-3025	2135	3	lovheim	lovheim	PROPN
fnp-3025	2135	4	,	,	PUNCT
fnp-3025	2135	5	h.	h.	PROPN
fnp-3025	2135	6	,	,	PUNCT
fnp-3025	2135	7	et	et	PROPN
fnp-3025	2135	8	al	al	PROPN
fnp-3025	2135	9	.	.	PROPN
fnp-3025	2135	10	,	,	PUNCT
fnp-3025	2135	11	reactivated	reactivate	VERB
fnp-3025	2135	12	herpes	herpe	NOUN
fnp-3025	2135	13	simplex	simplex	NOUN
fnp-3025	2135	14	infection	infection	NOUN
fnp-3025	2135	15	increases	increase	VERB
fnp-3025	2135	16	the	the	DET
fnp-3025	2135	17	risk	risk	NOUN
fnp-3025	2135	18	of	of	ADP
fnp-3025	2135	19	alzheimer	alzheimer	PROPN
fnp-3025	2135	20	’s	’s	PART
fnp-3025	2135	21	disease	disease	NOUN
fnp-3025	2135	22	.	.	PUNCT
fnp-3025	2136	1	alzheimers	alzheimers	PROPN
fnp-3025	2136	2	dement	dement	PROPN
fnp-3025	2136	3	,	,	PUNCT
fnp-3025	2136	4	2015	2015	NUM
fnp-3025	2136	5	.	.	PUNCT
fnp-3025	2137	1	11(6	11(6	NUM
fnp-3025	2137	2	):	):	PUNCT
fnp-3025	2137	3	p.	p.	NOUN
fnp-3025	2137	4	593	593	NUM
fnp-3025	2137	5	-	-	SYM
fnp-3025	2137	6	9	9	NUM
fnp-3025	2137	7	.	.	NOUN
fnp-3025	2137	8	397	397	NUM
fnp-3025	2137	9	.	.	X
fnp-3025	2138	1	readhead	readhead	PROPN
fnp-3025	2138	2	,	,	PUNCT
fnp-3025	2138	3	b.	b.	PROPN
fnp-3025	2138	4	,	,	PUNCT
fnp-3025	2138	5	et	et	PROPN
fnp-3025	2138	6	al	al	PROPN
fnp-3025	2138	7	.	.	PROPN
fnp-3025	2138	8	,	,	PUNCT
fnp-3025	2138	9	multiscale	multiscale	ADJ
fnp-3025	2138	10	analysis	analysis	NOUN
fnp-3025	2138	11	of	of	ADP
fnp-3025	2138	12	independent	independent	ADJ
fnp-3025	2138	13	alzheimer	alzheimer	PROPN
fnp-3025	2138	14	’s	’s	PART
fnp-3025	2138	15	cohorts	cohort	NOUN
fnp-3025	2138	16	finds	find	VERB
fnp-3025	2138	17	disruption	disruption	NOUN
fnp-3025	2138	18	of	of	ADP
fnp-3025	2138	19	molecular	molecular	ADJ
fnp-3025	2138	20	,	,	PUNCT
fnp-3025	2138	21	genetic	genetic	ADJ
fnp-3025	2138	22	,	,	PUNCT
fnp-3025	2138	23	and	and	CCONJ
fnp-3025	2138	24	clinical	clinical	ADJ
fnp-3025	2138	25	networks	network	NOUN
fnp-3025	2138	26	by	by	ADP
fnp-3025	2138	27	human	human	ADJ
fnp-3025	2138	28	herpesvirus	herpesvirus	NOUN
fnp-3025	2138	29	.	.	PUNCT
fnp-3025	2139	1	neuron	neuron	PROPN
fnp-3025	2139	2	,	,	PUNCT
fnp-3025	2139	3	2018	2018	NUM
fnp-3025	2139	4	.	.	PUNCT
fnp-3025	2140	1	99(1	99(1	NUM
fnp-3025	2140	2	):	):	PUNCT
fnp-3025	2140	3	p.	p.	NOUN
fnp-3025	2140	4	64	64	NUM
fnp-3025	2140	5	-	-	SYM
fnp-3025	2140	6	82	82	NUM
fnp-3025	2140	7	e7	e7	PROPN
fnp-3025	2140	8	.	.	PUNCT
fnp-3025	2141	1	398	398	NUM
fnp-3025	2141	2	.	.	PUNCT
fnp-3025	2142	1	sochocka	sochocka	NOUN
fnp-3025	2142	2	,	,	PUNCT
fnp-3025	2142	3	m.	m.	NOUN
fnp-3025	2142	4	,	,	PUNCT
fnp-3025	2142	5	k.	k.	PROPN
fnp-3025	2142	6	zwolinska	zwolinska	PROPN
fnp-3025	2142	7	,	,	PUNCT
fnp-3025	2142	8	and	and	CCONJ
fnp-3025	2142	9	j.	j.	PROPN
fnp-3025	2142	10	leszek	leszek	PROPN
fnp-3025	2142	11	,	,	PUNCT
fnp-3025	2142	12	the	the	DET
fnp-3025	2142	13	infectious	infectious	ADJ
fnp-3025	2142	14	etiology	etiology	NOUN
fnp-3025	2142	15	of	of	ADP
fnp-3025	2142	16	alzheimer	alzheimer	PROPN
fnp-3025	2142	17	’s	’s	PART
fnp-3025	2142	18	disease	disease	NOUN
fnp-3025	2142	19	.	.	PUNCT
fnp-3025	2143	1	curr	curr	PROPN
fnp-3025	2143	2	neuropharmacol	neuropharmacol	PROPN
fnp-3025	2143	3	,	,	PUNCT
fnp-3025	2143	4	2017	2017	NUM
fnp-3025	2143	5	.	.	PUNCT
fnp-3025	2144	1	15(7	15(7	NUM
fnp-3025	2144	2	):	):	PUNCT
fnp-3025	2145	1	p.	p.	NOUN
fnp-3025	2145	2	996	996	NUM
fnp-3025	2145	3	-	-	SYM
fnp-3025	2145	4	1009	1009	NUM
fnp-3025	2145	5	.	.	PUNCT
fnp-3025	2146	1	399	399	NUM
fnp-3025	2146	2	.	.	PUNCT
fnp-3025	2147	1	rizzo	rizzo	PROPN
fnp-3025	2147	2	,	,	PUNCT
fnp-3025	2147	3	r.	r.	PROPN
fnp-3025	2147	4	,	,	PUNCT
fnp-3025	2147	5	controversial	controversial	ADJ
fnp-3025	2147	6	role	role	NOUN
fnp-3025	2147	7	of	of	ADP
fnp-3025	2147	8	herpesviruses	herpesviruse	NOUN
fnp-3025	2147	9	in	in	ADP
fnp-3025	2147	10	alzheimer	alzheimer	PROPN
fnp-3025	2147	11	’s	’s	PART
fnp-3025	2147	12	disease	disease	NOUN
fnp-3025	2147	13	.	.	PUNCT
fnp-3025	2148	1	plos	plos	PROPN
fnp-3025	2148	2	pathog	pathog	PROPN
fnp-3025	2148	3	,	,	PUNCT
fnp-3025	2148	4	2020	2020	NUM
fnp-3025	2148	5	.	.	PUNCT
fnp-3025	2149	1	16(6	16(6	NUM
fnp-3025	2149	2	):	):	PUNCT
fnp-3025	2149	3	p.	p.	NOUN
fnp-3025	2149	4	e1008575	e1008575	PROPN
fnp-3025	2149	5	.	.	PUNCT
fnp-3025	2150	1	400	400	NUM
fnp-3025	2150	2	.	.	PUNCT
fnp-3025	2151	1	mawanda	mawanda	PROPN
fnp-3025	2151	2	,	,	PUNCT
fnp-3025	2151	3	f.	f.	PROPN
fnp-3025	2151	4	and	and	CCONJ
fnp-3025	2151	5	r.	r.	PROPN
fnp-3025	2151	6	wallace	wallace	PROPN
fnp-3025	2151	7	,	,	PUNCT
fnp-3025	2151	8	can	can	AUX
fnp-3025	2151	9	infections	infection	NOUN
fnp-3025	2151	10	cause	cause	VERB
fnp-3025	2151	11	alzheimer	alzheimer	PROPN
fnp-3025	2151	12	’s	’s	PART
fnp-3025	2151	13	disease	disease	NOUN
fnp-3025	2151	14	?	?	PUNCT
fnp-3025	2152	1	epidemiol	epidemiol	PROPN
fnp-3025	2152	2	rev	rev	PROPN
fnp-3025	2152	3	,	,	PUNCT
fnp-3025	2152	4	2013	2013	NUM
fnp-3025	2152	5	.	.	PUNCT
fnp-3025	2153	1	35	35	NUM
fnp-3025	2153	2	:	:	PUNCT
fnp-3025	2154	1	p.	p.	NOUN
fnp-3025	2154	2	161	161	NUM
fnp-3025	2154	3	-	-	SYM
fnp-3025	2154	4	80	80	NUM
fnp-3025	2154	5	.	.	PUNCT
fnp-3025	2155	1	401	401	NUM
fnp-3025	2155	2	.	.	PUNCT
fnp-3025	2155	3	fulop	fulop	PROPN
fnp-3025	2155	4	,	,	PUNCT
fnp-3025	2155	5	t.	t.	PROPN
fnp-3025	2155	6	,	,	PUNCT
fnp-3025	2155	7	et	et	PROPN
fnp-3025	2155	8	al	al	PROPN
fnp-3025	2155	9	.	.	PROPN
fnp-3025	2155	10	,	,	PUNCT
fnp-3025	2155	11	role	role	NOUN
fnp-3025	2155	12	of	of	ADP
fnp-3025	2155	13	microbes	microbe	NOUN
fnp-3025	2155	14	in	in	ADP
fnp-3025	2155	15	the	the	DET
fnp-3025	2155	16	development	development	NOUN
fnp-3025	2155	17	of	of	ADP
fnp-3025	2155	18	alzheimer	alzheimer	PROPN
fnp-3025	2155	19	’s	’s	PART
fnp-3025	2155	20	disease	disease	NOUN
fnp-3025	2155	21	:	:	PUNCT
fnp-3025	2155	22	state	state	NOUN
fnp-3025	2155	23	of	of	ADP
fnp-3025	2155	24	the	the	DET
fnp-3025	2155	25	art	art	NOUN
fnp-3025	2155	26	an	an	DET
fnp-3025	2155	27	international	international	ADJ
fnp-3025	2155	28	symposium	symposium	NOUN
fnp-3025	2155	29	presented	present	VERB
fnp-3025	2155	30	at	at	ADP
fnp-3025	2155	31	the	the	DET
fnp-3025	2155	32	2017	2017	NUM
fnp-3025	2155	33	iagg	iagg	PROPN
fnp-3025	2155	34	congress	congress	PROPN
fnp-3025	2155	35	in	in	ADP
fnp-3025	2155	36	san	san	PROPN
fnp-3025	2155	37	francisco	francisco	PROPN
fnp-3025	2155	38	.	.	PUNCT
fnp-3025	2156	1	front	front	ADJ
fnp-3025	2156	2	genet	genet	NOUN
fnp-3025	2156	3	,	,	PUNCT
fnp-3025	2156	4	2018	2018	NUM
fnp-3025	2156	5	.	.	PUNCT
fnp-3025	2157	1	9	9	NUM
fnp-3025	2157	2	:	:	PUNCT
fnp-3025	2157	3	p.	p.	NOUN
fnp-3025	2157	4	362	362	NUM
fnp-3025	2157	5	.	.	PUNCT
fnp-3025	2158	1	402	402	NUM
fnp-3025	2158	2	.	.	PUNCT
fnp-3025	2159	1	fulop	fulop	NOUN
fnp-3025	2159	2	,	,	PUNCT
fnp-3025	2159	3	t.	t.	PROPN
fnp-3025	2159	4	,	,	PUNCT
fnp-3025	2159	5	et	et	PROPN
fnp-3025	2159	6	al	al	PROPN
fnp-3025	2159	7	.	.	PROPN
fnp-3025	2159	8	,	,	PUNCT
fnp-3025	2159	9	can	can	AUX
fnp-3025	2159	10	an	an	DET
fnp-3025	2159	11	infection	infection	NOUN
fnp-3025	2159	12	hypothesis	hypothesis	NOUN
fnp-3025	2159	13	explain	explain	VERB
fnp-3025	2159	14	the	the	DET
fnp-3025	2159	15	beta	beta	ADJ
fnp-3025	2159	16	amyloid	amyloid	NOUN
fnp-3025	2159	17	hypothesis	hypothesis	NOUN
fnp-3025	2159	18	of	of	ADP
fnp-3025	2159	19	alzheimer	alzheimer	PROPN
fnp-3025	2159	20	’s	’s	PART
fnp-3025	2159	21	disease	disease	NOUN
fnp-3025	2159	22	?	?	PUNCT
fnp-3025	2160	1	front	front	ADJ
fnp-3025	2160	2	aging	age	VERB
fnp-3025	2160	3	neurosci	neurosci	NOUN
fnp-3025	2160	4	,	,	PUNCT
fnp-3025	2160	5	2018	2018	NUM
fnp-3025	2160	6	.	.	PUNCT
fnp-3025	2161	1	10	10	NUM
fnp-3025	2161	2	:	:	PUNCT
fnp-3025	2161	3	p.	p.	NOUN
fnp-3025	2161	4	224	224	NUM
fnp-3025	2161	5	.	.	PUNCT
fnp-3025	2162	1	403	403	NUM
fnp-3025	2162	2	.	.	PUNCT
fnp-3025	2163	1	eimer	eimer	PROPN
fnp-3025	2163	2	,	,	PUNCT
fnp-3025	2163	3	w.a	w.a	PROPN
fnp-3025	2163	4	.	.	PROPN
fnp-3025	2163	5	,	,	PUNCT
fnp-3025	2163	6	et	et	PROPN
fnp-3025	2163	7	al	al	PROPN
fnp-3025	2163	8	.	.	PROPN
fnp-3025	2163	9	,	,	PUNCT
fnp-3025	2163	10	alzheimer	alzheimer	PROPN
fnp-3025	2163	11	’s	’s	PART
fnp-3025	2163	12	disease	disease	NOUN
fnp-3025	2163	13	-	-	PUNCT
fnp-3025	2163	14	associated	associate	VERB
fnp-3025	2163	15	beta	beta	NOUN
fnp-3025	2163	16	-	-	PUNCT
fnp-3025	2163	17	amyloid	amyloid	NOUN
fnp-3025	2163	18	is	be	AUX
fnp-3025	2163	19	rapidly	rapidly	ADV
fnp-3025	2163	20	seeded	seed	VERB
fnp-3025	2163	21	by	by	ADP
fnp-3025	2163	22	herpesviridae	herpesviridae	NOUN
fnp-3025	2163	23	to	to	PART
fnp-3025	2163	24	protect	protect	VERB
fnp-3025	2163	25	against	against	ADP
fnp-3025	2163	26	brain	brain	NOUN
fnp-3025	2163	27	infection	infection	NOUN
fnp-3025	2163	28	.	.	PUNCT
fnp-3025	2164	1	neuron	neuron	PROPN
fnp-3025	2164	2	,	,	PUNCT
fnp-3025	2164	3	2018	2018	NUM
fnp-3025	2164	4	.	.	PUNCT
fnp-3025	2165	1	99(1	99(1	NUM
fnp-3025	2165	2	):	):	PUNCT
fnp-3025	2165	3	p.	p.	NOUN
fnp-3025	2165	4	56	56	NUM
fnp-3025	2165	5	-	-	SYM
fnp-3025	2165	6	63	63	NUM
fnp-3025	2165	7	e3	e3	NOUN
fnp-3025	2165	8	.	.	PUNCT
fnp-3025	2166	1	404	404	NUM
fnp-3025	2166	2	.	.	PUNCT
fnp-3025	2167	1	soscia	soscia	PROPN
fnp-3025	2167	2	,	,	PUNCT
fnp-3025	2167	3	s.j	s.j	PROPN
fnp-3025	2167	4	.	.	PROPN
fnp-3025	2167	5	,	,	PUNCT
fnp-3025	2167	6	et	et	PROPN
fnp-3025	2167	7	al	al	PROPN
fnp-3025	2167	8	.	.	PROPN
fnp-3025	2167	9	,	,	PUNCT
fnp-3025	2167	10	the	the	DET
fnp-3025	2167	11	alzheimer	alzheimer	PROPN
fnp-3025	2167	12	’s	’s	PART
fnp-3025	2167	13	disease	disease	NOUN
fnp-3025	2167	14	-	-	PUNCT
fnp-3025	2167	15	associated	associate	VERB
fnp-3025	2167	16	amyloid	amyloid	NOUN
fnp-3025	2167	17	beta	beta	NOUN
fnp-3025	2167	18	-	-	PUNCT
fnp-3025	2167	19	protein	protein	NOUN
fnp-3025	2167	20	is	be	AUX
fnp-3025	2167	21	an	an	DET
fnp-3025	2167	22	antimicrobial	antimicrobial	ADJ
fnp-3025	2167	23	peptide	peptide	NOUN
fnp-3025	2167	24	.	.	PUNCT
fnp-3025	2168	1	plos	plos	PROPN
fnp-3025	2168	2	one	one	NUM
fnp-3025	2168	3	,	,	PUNCT
fnp-3025	2168	4	2010	2010	NUM
fnp-3025	2168	5	.	.	PUNCT
fnp-3025	2169	1	5(3	5(3	NUM
fnp-3025	2169	2	):	):	PUNCT
fnp-3025	2169	3	p.	p.	PROPN
fnp-3025	2169	4	e9505	e9505	PROPN
fnp-3025	2169	5	.	.	PUNCT
fnp-3025	2170	1	405	405	NUM
fnp-3025	2170	2	.	.	PUNCT
fnp-3025	2171	1	zhan	zhan	PROPN
fnp-3025	2171	2	,	,	PUNCT
fnp-3025	2171	3	x.	x.	PROPN
fnp-3025	2171	4	,	,	PUNCT
fnp-3025	2171	5	b.	b.	PROPN
fnp-3025	2171	6	stamova	stamova	PROPN
fnp-3025	2171	7	,	,	PUNCT
fnp-3025	2171	8	and	and	CCONJ
fnp-3025	2171	9	f.r	f.r	PROPN
fnp-3025	2171	10	.	.	PROPN
fnp-3025	2171	11	sharp	sharp	PROPN
fnp-3025	2171	12	,	,	PUNCT
fnp-3025	2171	13	lipopolysaccharide	lipopolysaccharide	PROPN
fnp-3025	2171	14	associates	associate	NOUN
fnp-3025	2171	15	with	with	ADP
fnp-3025	2171	16	amyloid	amyloid	NOUN
fnp-3025	2171	17	plaques	plaque	NOUN
fnp-3025	2171	18	,	,	PUNCT
fnp-3025	2171	19	neurons	neuron	NOUN
fnp-3025	2171	20	and	and	CCONJ
fnp-3025	2171	21	oligodendrocytes	oligodendrocyte	NOUN
fnp-3025	2171	22	in	in	ADP
fnp-3025	2171	23	alzheimer	alzheimer	PROPN
fnp-3025	2171	24	’s	’s	PART
fnp-3025	2171	25	disease	disease	NOUN
fnp-3025	2171	26	brain	brain	NOUN
fnp-3025	2171	27	:	:	PUNCT
fnp-3025	2171	28	a	a	DET
fnp-3025	2171	29	review	review	NOUN
fnp-3025	2171	30	.	.	PUNCT
fnp-3025	2172	1	front	front	ADJ
fnp-3025	2172	2	aging	age	VERB
fnp-3025	2172	3	neurosci	neurosci	NOUN
fnp-3025	2172	4	,	,	PUNCT
fnp-3025	2172	5	2018	2018	NUM
fnp-3025	2172	6	.	.	PUNCT
fnp-3025	2173	1	10	10	NUM
fnp-3025	2173	2	:	:	PUNCT
fnp-3025	2174	1	p.	p.	NOUN
fnp-3025	2174	2	42	42	NUM
fnp-3025	2174	3	.	.	PUNCT
fnp-3025	2174	4	406	406	NUM
fnp-3025	2174	5	.	.	PUNCT
fnp-3025	2175	1	harach	harach	NOUN
fnp-3025	2175	2	,	,	PUNCT
fnp-3025	2175	3	t.	t.	PROPN
fnp-3025	2175	4	,	,	PUNCT
fnp-3025	2175	5	et	et	PROPN
fnp-3025	2175	6	al	al	PROPN
fnp-3025	2175	7	.	.	PROPN
fnp-3025	2175	8	,	,	PUNCT
fnp-3025	2175	9	reduction	reduction	NOUN
fnp-3025	2175	10	of	of	ADP
fnp-3025	2175	11	abeta	abeta	PROPN
fnp-3025	2175	12	amyloid	amyloid	NOUN
fnp-3025	2175	13	pathology	pathology	NOUN
fnp-3025	2175	14	in	in	ADP
fnp-3025	2175	15	appps1	appps1	NOUN
fnp-3025	2175	16	transgenic	transgenic	NOUN
fnp-3025	2175	17	mice	mouse	NOUN
fnp-3025	2175	18	in	in	ADP
fnp-3025	2175	19	the	the	DET
fnp-3025	2175	20	absence	absence	NOUN
fnp-3025	2175	21	of	of	ADP
fnp-3025	2175	22	gut	gut	NOUN
fnp-3025	2175	23	microbiota	microbiota	NOUN
fnp-3025	2175	24	.	.	PUNCT
fnp-3025	2176	1	sci	sci	PROPN
fnp-3025	2176	2	rep	rep	PROPN
fnp-3025	2176	3	,	,	PUNCT
fnp-3025	2176	4	2017	2017	NUM
fnp-3025	2176	5	.	.	PUNCT
fnp-3025	2177	1	7	7	NUM
fnp-3025	2177	2	:	:	PUNCT
fnp-3025	2177	3	p.	p.	NOUN
fnp-3025	2177	4	41802	41802	NUM
fnp-3025	2177	5	.	.	PUNCT
fnp-3025	2178	1	407	407	NUM
fnp-3025	2178	2	.	.	PUNCT
fnp-3025	2179	1	jucker	jucker	NOUN
fnp-3025	2179	2	,	,	PUNCT
fnp-3025	2179	3	m.	m.	NOUN
fnp-3025	2179	4	and	and	CCONJ
fnp-3025	2179	5	l.c	l.c	PROPN
fnp-3025	2179	6	.	.	PROPN
fnp-3025	2179	7	walker	walker	PROPN
fnp-3025	2179	8	,	,	PUNCT
fnp-3025	2179	9	propagation	propagation	NOUN
fnp-3025	2179	10	and	and	CCONJ
fnp-3025	2179	11	spread	spread	VERB
fnp-3025	2179	12	of	of	ADP
fnp-3025	2179	13	pathogenic	pathogenic	ADJ
fnp-3025	2179	14	protein	protein	NOUN
fnp-3025	2179	15	assemblies	assembly	NOUN
fnp-3025	2179	16	in	in	ADP
fnp-3025	2179	17	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2179	18	diseases	disease	NOUN
fnp-3025	2179	19	.	.	PUNCT
fnp-3025	2180	1	nat	nat	PROPN
fnp-3025	2180	2	neurosci	neurosci	PROPN
fnp-3025	2180	3	,	,	PUNCT
fnp-3025	2180	4	2018	2018	NUM
fnp-3025	2180	5	.	.	PUNCT
fnp-3025	2181	1	21(10	21(10	NUM
fnp-3025	2181	2	):	):	PUNCT
fnp-3025	2181	3	p.	p.	NOUN
fnp-3025	2181	4	1341	1341	NUM
fnp-3025	2181	5	-	-	SYM
fnp-3025	2181	6	1349	1349	NUM
fnp-3025	2181	7	.	.	PUNCT
fnp-3025	2182	1	408	408	NUM
fnp-3025	2182	2	.	.	PUNCT
fnp-3025	2183	1	jaunmuktane	jaunmuktane	NOUN
fnp-3025	2183	2	,	,	PUNCT
fnp-3025	2183	3	z.	z.	PROPN
fnp-3025	2183	4	and	and	CCONJ
fnp-3025	2183	5	s.	s.	PROPN
fnp-3025	2183	6	brandner	brandner	PROPN
fnp-3025	2183	7	,	,	PUNCT
fnp-3025	2183	8	invited	invite	VERB
fnp-3025	2183	9	review	review	NOUN
fnp-3025	2183	10	:	:	PUNCT
fnp-3025	2183	11	the	the	DET
fnp-3025	2183	12	role	role	NOUN
fnp-3025	2183	13	of	of	ADP
fnp-3025	2183	14	prion	prion	NOUN
fnp-3025	2183	15	-	-	PUNCT
fnp-3025	2183	16	like	like	ADJ
fnp-3025	2183	17	mechanisms	mechanism	NOUN
fnp-3025	2183	18	in	in	ADP
fnp-3025	2183	19	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2183	20	diseases	disease	NOUN
fnp-3025	2183	21	.	.	PUNCT
fnp-3025	2184	1	neuropathol	neuropathol	PROPN
fnp-3025	2184	2	appl	appl	PROPN
fnp-3025	2184	3	neurobiol	neurobiol	PROPN
fnp-3025	2184	4	,	,	PUNCT
fnp-3025	2184	5	2019	2019	NUM
fnp-3025	2184	6	.	.	PUNCT
fnp-3025	2185	1	46(6	46(6	X
fnp-3025	2185	2	):	):	PUNCT
fnp-3025	2185	3	p.	p.	NOUN
fnp-3025	2185	4	522	522	NUM
fnp-3025	2185	5	-	-	SYM
fnp-3025	2185	6	545	545	NUM
fnp-3025	2185	7	.	.	PUNCT
fnp-3025	2185	8	409	409	NUM
fnp-3025	2185	9	.	.	PUNCT
fnp-3025	2186	1	ayers	ayers	PROPN
fnp-3025	2186	2	,	,	PUNCT
fnp-3025	2186	3	j.i	j.i	PROPN
fnp-3025	2186	4	.	.	PROPN
fnp-3025	2186	5	,	,	PUNCT
fnp-3025	2186	6	n.a	n.a	PROPN
fnp-3025	2186	7	.	.	PROPN
fnp-3025	2186	8	paras	para	NOUN
fnp-3025	2186	9	,	,	PUNCT
fnp-3025	2186	10	and	and	CCONJ
fnp-3025	2186	11	s.b	s.b	PROPN
fnp-3025	2186	12	.	.	PROPN
fnp-3025	2186	13	prusiner	prusiner	NOUN
fnp-3025	2186	14	,	,	PUNCT
fnp-3025	2186	15	expanding	expand	VERB
fnp-3025	2186	16	spectrum	spectrum	NOUN
fnp-3025	2186	17	of	of	ADP
fnp-3025	2186	18	prion	prion	NOUN
fnp-3025	2186	19	diseases	disease	NOUN
fnp-3025	2186	20	.	.	PUNCT
fnp-3025	2187	1	emerging	emerge	VERB
fnp-3025	2187	2	topics	topic	NOUN
fnp-3025	2187	3	in	in	ADP
fnp-3025	2187	4	life	life	NOUN
fnp-3025	2187	5	sciences	science	NOUN
fnp-3025	2187	6	,	,	PUNCT
fnp-3025	2187	7	2020	2020	NUM
fnp-3025	2187	8	:	:	PUNCT
fnp-3025	2187	9	p.	p.	NOUN
fnp-3025	2187	10	1	1	NUM
fnp-3025	2187	11	-	-	SYM
fnp-3025	2187	12	13	13	NUM
fnp-3025	2187	13	.	.	PUNCT
fnp-3025	2187	14	410	410	NUM
fnp-3025	2187	15	.	.	PUNCT
fnp-3025	2188	1	prusiner	prusiner	NOUN
fnp-3025	2188	2	,	,	PUNCT
fnp-3025	2188	3	s.b	s.b	PROPN
fnp-3025	2188	4	.	.	PROPN
fnp-3025	2188	5	,	,	PUNCT
fnp-3025	2188	6	development	development	NOUN
fnp-3025	2188	7	of	of	ADP
fnp-3025	2188	8	the	the	DET
fnp-3025	2188	9	prion	prion	NOUN
fnp-3025	2188	10	concept	concept	NOUN
fnp-3025	2188	11	,	,	PUNCT
fnp-3025	2188	12	in	in	ADP
fnp-3025	2188	13	prion	prion	NOUN
fnp-3025	2188	14	biology	biology	NOUN
fnp-3025	2188	15	and	and	CCONJ
fnp-3025	2188	16	diseases	disease	NOUN
fnp-3025	2188	17	,	,	PUNCT
fnp-3025	2188	18	s.b	s.b	PROPN
fnp-3025	2188	19	.	.	PROPN
fnp-3025	2188	20	prusiner	prusiner	NOUN
fnp-3025	2188	21	,	,	PUNCT
fnp-3025	2188	22	editor	editor	NOUN
fnp-3025	2188	23	.	.	PUNCT
fnp-3025	2189	1	2004	2004	NUM
fnp-3025	2189	2	,	,	PUNCT
fnp-3025	2189	3	cold	cold	ADJ
fnp-3025	2189	4	spring	spring	NOUN
fnp-3025	2189	5	harbor	harbor	NOUN
fnp-3025	2189	6	laboratory	laboratory	PROPN
fnp-3025	2189	7	press	press	PROPN
fnp-3025	2189	8	:	:	PUNCT
fnp-3025	2189	9	cold	cold	ADJ
fnp-3025	2189	10	spring	spring	NOUN
fnp-3025	2189	11	harbor	harbor	NOUN
fnp-3025	2189	12	.	.	PUNCT
fnp-3025	2190	1	p.	p.	NOUN
fnp-3025	2190	2	89	89	NUM
fnp-3025	2190	3	-	-	SYM
fnp-3025	2190	4	141	141	NUM
fnp-3025	2190	5	.	.	PUNCT
fnp-3025	2191	1	411	411	NUM
fnp-3025	2191	2	.	.	PUNCT
fnp-3025	2192	1	zabel	zabel	PROPN
fnp-3025	2192	2	,	,	PUNCT
fnp-3025	2192	3	m.d	m.d	PROPN
fnp-3025	2192	4	.	.	PROPN
fnp-3025	2192	5	and	and	CCONJ
fnp-3025	2192	6	c.	c.	PROPN
fnp-3025	2192	7	reid	reid	PROPN
fnp-3025	2192	8	,	,	PUNCT
fnp-3025	2192	9	a	a	DET
fnp-3025	2192	10	brief	brief	ADJ
fnp-3025	2192	11	history	history	NOUN
fnp-3025	2192	12	of	of	ADP
fnp-3025	2192	13	prions	prion	NOUN
fnp-3025	2192	14	.	.	PUNCT
fnp-3025	2193	1	pathog	pathog	PROPN
fnp-3025	2193	2	dis	dis	PROPN
fnp-3025	2193	3	,	,	PUNCT
fnp-3025	2193	4	2015	2015	NUM
fnp-3025	2193	5	.	.	PUNCT
fnp-3025	2194	1	73(9	73(9	NUM
fnp-3025	2194	2	):	):	PUNCT
fnp-3025	2195	1	p.	p.	PROPN
fnp-3025	2195	2	ftv087	ftv087	PROPN
fnp-3025	2195	3	.	.	PUNCT
fnp-3025	2196	1	412	412	NUM
fnp-3025	2196	2	.	.	PUNCT
fnp-3025	2196	3	prusiner	prusiner	NOUN
fnp-3025	2196	4	,	,	PUNCT
fnp-3025	2196	5	s.b	s.b	PROPN
fnp-3025	2196	6	.	.	PROPN
fnp-3025	2196	7	,	,	PUNCT
fnp-3025	2196	8	prions	prion	NOUN
fnp-3025	2196	9	.	.	PUNCT
fnp-3025	2197	1	proc	proc	PROPN
fnp-3025	2197	2	natl	natl	PROPN
fnp-3025	2197	3	acad	acad	PROPN
fnp-3025	2197	4	sci	sci	PROPN
fnp-3025	2197	5	u	u	PROPN
fnp-3025	2197	6	s	s	PROPN
fnp-3025	2197	7	a	a	PRON
fnp-3025	2197	8	,	,	PUNCT
fnp-3025	2197	9	1998	1998	NUM
fnp-3025	2197	10	.	.	PUNCT
fnp-3025	2198	1	95(23	95(23	NOUN
fnp-3025	2198	2	):	):	PUNCT
fnp-3025	2198	3	p.	p.	NOUN
fnp-3025	2198	4	13363	13363	NUM
fnp-3025	2198	5	-	-	SYM
fnp-3025	2198	6	83	83	NUM
fnp-3025	2198	7	.	.	PUNCT
fnp-3025	2199	1	413	413	NUM
fnp-3025	2199	2	.	.	PUNCT
fnp-3025	2200	1	friesen	friesen	PROPN
fnp-3025	2200	2	,	,	PUNCT
fnp-3025	2200	3	m.	m.	NOUN
fnp-3025	2200	4	and	and	CCONJ
fnp-3025	2200	5	m.	m.	PROPN
fnp-3025	2200	6	meyer	meyer	PROPN
fnp-3025	2200	7	-	-	PUNCT
fnp-3025	2200	8	luehmann	luehmann	PROPN
fnp-3025	2200	9	,	,	PUNCT
fnp-3025	2200	10	abeta	abeta	NOUN
fnp-3025	2200	11	seeding	seeding	NOUN
fnp-3025	2200	12	as	as	ADP
fnp-3025	2200	13	a	a	DET
fnp-3025	2200	14	tool	tool	NOUN
fnp-3025	2200	15	to	to	PART
fnp-3025	2200	16	study	study	VERB
fnp-3025	2200	17	cerebral	cerebral	ADJ
fnp-3025	2200	18	amyloidosis	amyloidosis	NOUN
fnp-3025	2200	19	and	and	CCONJ
fnp-3025	2200	20	associated	associated	ADJ
fnp-3025	2200	21	pathology	pathology	NOUN
fnp-3025	2200	22	.	.	PUNCT
fnp-3025	2201	1	front	front	PROPN
fnp-3025	2201	2	mol	mol	ADP
fnp-3025	2201	3	neurosci	neurosci	PROPN
fnp-3025	2201	4	,	,	PUNCT
fnp-3025	2201	5	2019	2019	NUM
fnp-3025	2201	6	.	.	PUNCT
fnp-3025	2202	1	12	12	NUM
fnp-3025	2202	2	:	:	PUNCT
fnp-3025	2202	3	p.	p.	NOUN
fnp-3025	2202	4	233	233	NUM
fnp-3025	2202	5	.	.	PUNCT
fnp-3025	2203	1	414	414	NUM
fnp-3025	2203	2	.	.	PUNCT
fnp-3025	2204	1	morales	morale	NOUN
fnp-3025	2204	2	,	,	PUNCT
fnp-3025	2204	3	r.	r.	PROPN
fnp-3025	2204	4	,	,	PUNCT
fnp-3025	2204	5	k.	k.	PROPN
fnp-3025	2204	6	callegari	callegari	PROPN
fnp-3025	2204	7	,	,	PUNCT
fnp-3025	2204	8	and	and	CCONJ
fnp-3025	2204	9	c.	c.	PROPN
fnp-3025	2204	10	soto	soto	PROPN
fnp-3025	2204	11	,	,	PUNCT
fnp-3025	2204	12	prion	prion	NOUN
fnp-3025	2204	13	-	-	PUNCT
fnp-3025	2204	14	like	like	ADJ
fnp-3025	2204	15	features	feature	NOUN
fnp-3025	2204	16	of	of	ADP
fnp-3025	2204	17	misfolded	misfolde	VERB
fnp-3025	2204	18	abeta	abeta	PROPN
fnp-3025	2204	19	and	and	CCONJ
fnp-3025	2204	20	tau	tau	PROPN
fnp-3025	2204	21	aggregates	aggregate	NOUN
fnp-3025	2204	22	.	.	PUNCT
fnp-3025	2205	1	virus	virus	NOUN
fnp-3025	2205	2	res	re	NOUN
fnp-3025	2205	3	,	,	PUNCT
fnp-3025	2205	4	2015	2015	NUM
fnp-3025	2205	5	.	.	PUNCT
fnp-3025	2206	1	207	207	NUM
fnp-3025	2206	2	:	:	PUNCT
fnp-3025	2207	1	p.	p.	NOUN
fnp-3025	2207	2	106	106	NUM
fnp-3025	2207	3	-	-	SYM
fnp-3025	2207	4	12	12	NUM
fnp-3025	2207	5	.	.	PUNCT
fnp-3025	2207	6	415	415	NUM
fnp-3025	2207	7	.	.	PUNCT
fnp-3025	2208	1	watts	watts	PROPN
fnp-3025	2208	2	,	,	PUNCT
fnp-3025	2208	3	j.c	j.c	PROPN
fnp-3025	2208	4	.	.	PROPN
fnp-3025	2208	5	and	and	CCONJ
fnp-3025	2208	6	s.b	s.b	PROPN
fnp-3025	2208	7	.	.	PROPN
fnp-3025	2208	8	prusiner	prusiner	NOUN
fnp-3025	2208	9	,	,	PUNCT
fnp-3025	2208	10	beta	beta	NOUN
fnp-3025	2208	11	-	-	PUNCT
fnp-3025	2208	12	amyloid	amyloid	NOUN
fnp-3025	2208	13	prions	prion	NOUN
fnp-3025	2208	14	and	and	CCONJ
fnp-3025	2208	15	the	the	DET
fnp-3025	2208	16	pathobiology	pathobiology	NOUN
fnp-3025	2208	17	of	of	ADP
fnp-3025	2208	18	alzheimer	alzheimer	PROPN
fnp-3025	2208	19	’s	’s	PART
fnp-3025	2208	20	disease	disease	NOUN
fnp-3025	2208	21	.	.	PUNCT
fnp-3025	2209	1	cold	cold	ADJ
fnp-3025	2209	2	spring	spring	NOUN
fnp-3025	2209	3	harb	harb	PROPN
fnp-3025	2209	4	perspect	perspect	PROPN
fnp-3025	2209	5	med	me	VERB
fnp-3025	2209	6	,	,	PUNCT
fnp-3025	2209	7	2018	2018	NUM
fnp-3025	2209	8	.	.	PUNCT
fnp-3025	2210	1	8(5	8(5	NUM
fnp-3025	2210	2	):	):	PUNCT
fnp-3025	2210	3	p.	p.	PROPN
fnp-3025	2210	4	a023507	a023507	PROPN
fnp-3025	2210	5	.	.	PUNCT
fnp-3025	2211	1	416	416	NUM
fnp-3025	2211	2	.	.	PUNCT
fnp-3025	2212	1	asher	asher	PROPN
fnp-3025	2212	2	,	,	PUNCT
fnp-3025	2212	3	d.m	d.m	PROPN
fnp-3025	2212	4	.	.	PROPN
fnp-3025	2212	5	,	,	PUNCT
fnp-3025	2212	6	et	et	PROPN
fnp-3025	2212	7	al	al	PROPN
fnp-3025	2212	8	.	.	PROPN
fnp-3025	2212	9	,	,	PUNCT
fnp-3025	2212	10	risk	risk	NOUN
fnp-3025	2212	11	of	of	ADP
fnp-3025	2212	12	transmissibility	transmissibility	NOUN
fnp-3025	2212	13	from	from	ADP
fnp-3025	2212	14	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2212	15	disease	disease	NOUN
fnp-3025	2212	16	-	-	PUNCT
fnp-3025	2212	17	associated	associate	VERB
fnp-3025	2212	18	proteins	protein	NOUN
fnp-3025	2212	19	:	:	PUNCT
fnp-3025	2212	20	experimental	experimental	ADJ
fnp-3025	2212	21	knowns	known	NOUN
fnp-3025	2212	22	and	and	CCONJ
fnp-3025	2212	23	unknowns	unknown	NOUN
fnp-3025	2212	24	.	.	PUNCT
fnp-3025	2213	1	j	j	PROPN
fnp-3025	2213	2	neuropathol	neuropathol	PROPN
fnp-3025	2213	3	exp	exp	PROPN
fnp-3025	2213	4	neurol	neurol	PROPN
fnp-3025	2213	5	,	,	PUNCT
fnp-3025	2213	6	2020	2020	NUM
fnp-3025	2213	7	.	.	PUNCT
fnp-3025	2214	1	79(11	79(11	NUM
fnp-3025	2214	2	):	):	PUNCT
fnp-3025	2214	3	p.	p.	NOUN
fnp-3025	2214	4	1141	1141	NUM
fnp-3025	2214	5	-	-	SYM
fnp-3025	2214	6	1146	1146	NUM
fnp-3025	2214	7	.	.	PUNCT
fnp-3025	2215	1	417	417	NUM
fnp-3025	2215	2	.	.	X
fnp-3025	2215	3	lauwers	lauwer	NOUN
fnp-3025	2215	4	,	,	PUNCT
fnp-3025	2215	5	e.	e.	PROPN
fnp-3025	2215	6	,	,	PUNCT
fnp-3025	2215	7	et	et	PROPN
fnp-3025	2215	8	al	al	PROPN
fnp-3025	2215	9	.	.	PROPN
fnp-3025	2215	10	,	,	PUNCT
fnp-3025	2215	11	potential	potential	ADJ
fnp-3025	2215	12	human	human	ADJ
fnp-3025	2215	13	transmission	transmission	NOUN
fnp-3025	2215	14	of	of	ADP
fnp-3025	2215	15	amyloid	amyloid	NOUN
fnp-3025	2215	16	β	β	X
fnp-3025	2215	17	pathology	pathology	NOUN
fnp-3025	2215	18	:	:	PUNCT
fnp-3025	2215	19	surveillance	surveillance	NOUN
fnp-3025	2215	20	and	and	CCONJ
fnp-3025	2215	21	risks	risk	NOUN
fnp-3025	2215	22	.	.	PUNCT
fnp-3025	2216	1	lancet	lancet	NOUN
fnp-3025	2216	2	neurology	neurology	NOUN
fnp-3025	2216	3	,	,	PUNCT
fnp-3025	2216	4	2020	2020	NUM
fnp-3025	2216	5	.	.	PUNCT
fnp-3025	2217	1	19	19	NUM
fnp-3025	2217	2	:	:	PUNCT
fnp-3025	2217	3	p.	p.	NOUN
fnp-3025	2217	4	872	872	NUM
fnp-3025	2217	5	-	-	SYM
fnp-3025	2217	6	878	878	NUM
fnp-3025	2217	7	.	.	PUNCT
fnp-3025	2218	1	418	418	NUM
fnp-3025	2218	2	.	.	PUNCT
fnp-3025	2219	1	brown	brown	PROPN
fnp-3025	2219	2	,	,	PUNCT
fnp-3025	2219	3	p.	p.	PROPN
fnp-3025	2219	4	,	,	PUNCT
fnp-3025	2219	5	et	et	PROPN
fnp-3025	2219	6	al	al	PROPN
fnp-3025	2219	7	.	.	PROPN
fnp-3025	2219	8	,	,	PUNCT
fnp-3025	2219	9	iatrogenic	iatrogenic	ADJ
fnp-3025	2219	10	creutzfeldt	creutzfeldt	ADJ
fnp-3025	2219	11	-	-	PUNCT
fnp-3025	2219	12	jakob	jakob	ADJ
fnp-3025	2219	13	disease	disease	NOUN
fnp-3025	2219	14	,	,	PUNCT
fnp-3025	2219	15	final	final	ADJ
fnp-3025	2219	16	assessment	assessment	NOUN
fnp-3025	2219	17	.	.	PUNCT
fnp-3025	2220	1	emerg	emerg	PROPN
fnp-3025	2220	2	infect	infect	PROPN
fnp-3025	2220	3	dis	dis	PROPN
fnp-3025	2220	4	,	,	PUNCT
fnp-3025	2220	5	2012	2012	NUM
fnp-3025	2220	6	.	.	PUNCT
fnp-3025	2221	1	18(6	18(6	NOUN
fnp-3025	2221	2	):	):	PUNCT
fnp-3025	2222	1	p.	p.	NOUN
fnp-3025	2222	2	901	901	NUM
fnp-3025	2222	3	-	-	SYM
fnp-3025	2222	4	7	7	NUM
fnp-3025	2222	5	.	.	NUM
fnp-3025	2222	6	419	419	NUM
fnp-3025	2222	7	.	.	PUNCT
fnp-3025	2223	1	will	will	AUX
fnp-3025	2223	2	,	,	PUNCT
fnp-3025	2223	3	r.g	r.g	AUX
fnp-3025	2223	4	.	.	PROPN
fnp-3025	2223	5	,	,	PUNCT
fnp-3025	2223	6	acquired	acquire	VERB
fnp-3025	2223	7	prion	prion	NOUN
fnp-3025	2223	8	disease	disease	NOUN
fnp-3025	2223	9	:	:	PUNCT
fnp-3025	2223	10	iatrogenic	iatrogenic	ADJ
fnp-3025	2223	11	cjd	cjd	NOUN
fnp-3025	2223	12	,	,	PUNCT
fnp-3025	2223	13	variant	variant	ADJ
fnp-3025	2223	14	cjd	cjd	NOUN
fnp-3025	2223	15	,	,	PUNCT
fnp-3025	2223	16	kuru	kuru	NOUN
fnp-3025	2223	17	.	.	PUNCT
fnp-3025	2224	1	br	br	PROPN
fnp-3025	2224	2	med	med	PROPN
fnp-3025	2224	3	bull	bull	NOUN
fnp-3025	2224	4	,	,	PUNCT
fnp-3025	2224	5	2003	2003	NUM
fnp-3025	2224	6	.	.	PUNCT
fnp-3025	2225	1	66	66	NUM
fnp-3025	2225	2	:	:	PUNCT
fnp-3025	2226	1	p.	p.	NOUN
fnp-3025	2226	2	255	255	NUM
fnp-3025	2226	3	-	-	SYM
fnp-3025	2226	4	65	65	NUM
fnp-3025	2226	5	.	.	PUNCT
fnp-3025	2226	6	420	420	NUM
fnp-3025	2226	7	.	.	PUNCT
fnp-3025	2227	1	jaunmuktane	jaunmuktane	NOUN
fnp-3025	2227	2	,	,	PUNCT
fnp-3025	2227	3	z.	z.	PROPN
fnp-3025	2227	4	,	,	PUNCT
fnp-3025	2227	5	et	et	PROPN
fnp-3025	2227	6	al	al	PROPN
fnp-3025	2227	7	.	.	PROPN
fnp-3025	2227	8	,	,	PUNCT
fnp-3025	2227	9	evidence	evidence	NOUN
fnp-3025	2227	10	for	for	ADP
fnp-3025	2227	11	human	human	ADJ
fnp-3025	2227	12	transmission	transmission	NOUN
fnp-3025	2227	13	of	of	ADP
fnp-3025	2227	14	amyloid	amyloid	NOUN
fnp-3025	2227	15	-	-	PUNCT
fnp-3025	2227	16	beta	beta	NOUN
fnp-3025	2227	17	pathology	pathology	NOUN
fnp-3025	2227	18	and	and	CCONJ
fnp-3025	2227	19	cerebral	cerebral	ADJ
fnp-3025	2227	20	amyloid	amyloid	NOUN
fnp-3025	2227	21	angiopathy	angiopathy	NOUN
fnp-3025	2227	22	.	.	PUNCT
fnp-3025	2228	1	nature	nature	NOUN
fnp-3025	2228	2	,	,	PUNCT
fnp-3025	2228	3	2015	2015	NUM
fnp-3025	2228	4	.	.	PUNCT
fnp-3025	2229	1	525(7568	525(7568	NUM
fnp-3025	2229	2	):	):	PUNCT
fnp-3025	2229	3	p.	p.	NOUN
fnp-3025	2229	4	247	247	NUM
fnp-3025	2229	5	-	-	SYM
fnp-3025	2229	6	50	50	NUM
fnp-3025	2229	7	.	.	PUNCT
fnp-3025	2230	1	421	421	NUM
fnp-3025	2230	2	.	.	PUNCT
fnp-3025	2231	1	ritchie	ritchie	PROPN
fnp-3025	2231	2	,	,	PUNCT
fnp-3025	2231	3	d.l	d.l	PROPN
fnp-3025	2231	4	.	.	PROPN
fnp-3025	2231	5	,	,	PUNCT
fnp-3025	2231	6	et	et	PROPN
fnp-3025	2231	7	al	al	PROPN
fnp-3025	2231	8	.	.	PROPN
fnp-3025	2231	9	,	,	PUNCT
fnp-3025	2231	10	amyloid	amyloid	NOUN
fnp-3025	2231	11	-	-	PUNCT
fnp-3025	2231	12	beta	beta	NOUN
fnp-3025	2231	13	accumulation	accumulation	NOUN
fnp-3025	2231	14	in	in	ADP
fnp-3025	2231	15	the	the	DET
fnp-3025	2231	16	cns	cns	NOUN
fnp-3025	2231	17	in	in	ADP
fnp-3025	2231	18	human	human	ADJ
fnp-3025	2231	19	growth	growth	NOUN
fnp-3025	2231	20	hormone	hormone	NOUN
fnp-3025	2231	21	recipients	recipient	NOUN
fnp-3025	2231	22	in	in	ADP
fnp-3025	2231	23	the	the	DET
fnp-3025	2231	24	uk	uk	PROPN
fnp-3025	2231	25	.	.	PROPN
fnp-3025	2231	26	acta	acta	PROPN
fnp-3025	2231	27	neuropathol	neuropathol	PROPN
fnp-3025	2231	28	,	,	PUNCT
fnp-3025	2231	29	2017	2017	NUM
fnp-3025	2231	30	.	.	PUNCT
fnp-3025	2232	1	134(2	134(2	NUM
fnp-3025	2232	2	):	):	PUNCT
fnp-3025	2232	3	p.	p.	NOUN
fnp-3025	2232	4	221	221	NUM
fnp-3025	2232	5	-	-	SYM
fnp-3025	2232	6	240	240	NUM
fnp-3025	2232	7	.	.	PUNCT
fnp-3025	2232	8	422	422	NUM
fnp-3025	2232	9	.	.	PUNCT
fnp-3025	2233	1	frontzek	frontzek	PROPN
fnp-3025	2233	2	,	,	PUNCT
fnp-3025	2233	3	k.	k.	PROPN
fnp-3025	2233	4	,	,	PUNCT
fnp-3025	2233	5	et	et	PROPN
fnp-3025	2233	6	al	al	PROPN
fnp-3025	2233	7	.	.	PROPN
fnp-3025	2233	8	,	,	PUNCT
fnp-3025	2233	9	amyloid	amyloid	NOUN
fnp-3025	2233	10	-	-	PUNCT
fnp-3025	2233	11	beta	beta	NOUN
fnp-3025	2233	12	pathology	pathology	NOUN
fnp-3025	2233	13	and	and	CCONJ
fnp-3025	2233	14	cerebral	cerebral	ADJ
fnp-3025	2233	15	amyloid	amyloid	NOUN
fnp-3025	2233	16	angiopathy	angiopathy	NOUN
fnp-3025	2233	17	are	be	AUX
fnp-3025	2233	18	frequent	frequent	ADJ
fnp-3025	2233	19	in	in	ADP
fnp-3025	2233	20	iatrogenic	iatrogenic	ADJ
fnp-3025	2233	21	creutzfeldt	creutzfeldt	ADJ
fnp-3025	2233	22	-	-	PUNCT
fnp-3025	2233	23	jakob	jakob	ADJ
fnp-3025	2233	24	disease	disease	NOUN
fnp-3025	2233	25	after	after	ADP
fnp-3025	2233	26	dural	dural	ADJ
fnp-3025	2233	27	grafting	grafting	NOUN
fnp-3025	2233	28	.	.	PUNCT
fnp-3025	2234	1	swiss	swiss	ADJ
fnp-3025	2234	2	med	med	ADJ
fnp-3025	2234	3	wkly	wkly	ADV
fnp-3025	2234	4	,	,	PUNCT
fnp-3025	2234	5	2016	2016	NUM
fnp-3025	2234	6	.	.	PUNCT
fnp-3025	2235	1	146	146	NUM
fnp-3025	2235	2	:	:	PUNCT
fnp-3025	2236	1	p.	p.	PROPN
fnp-3025	2236	2	w14287	w14287	PROPN
fnp-3025	2236	3	.	.	PUNCT
fnp-3025	2237	1	423	423	NUM
fnp-3025	2237	2	.	.	PUNCT
fnp-3025	2238	1	hamaguchi	hamaguchi	PROPN
fnp-3025	2238	2	,	,	PUNCT
fnp-3025	2238	3	t.	t.	PROPN
fnp-3025	2238	4	,	,	PUNCT
fnp-3025	2238	5	et	et	PROPN
fnp-3025	2238	6	al	al	PROPN
fnp-3025	2238	7	.	.	PROPN
fnp-3025	2238	8	,	,	PUNCT
fnp-3025	2238	9	significant	significant	ADJ
fnp-3025	2238	10	association	association	NOUN
fnp-3025	2238	11	of	of	ADP
fnp-3025	2238	12	cadaveric	cadaveric	ADJ
fnp-3025	2238	13	dura	dura	NOUN
fnp-3025	2238	14	mater	mater	NOUN
fnp-3025	2238	15	grafting	graft	VERB
fnp-3025	2238	16	with	with	ADP
fnp-3025	2238	17	subpial	subpial	ADJ
fnp-3025	2238	18	abeta	abeta	NOUN
fnp-3025	2238	19	deposition	deposition	NOUN
fnp-3025	2238	20	and	and	CCONJ
fnp-3025	2238	21	meningeal	meningeal	ADJ
fnp-3025	2238	22	amyloid	amyloid	NOUN
fnp-3025	2238	23	angiopathy	angiopathy	NOUN
fnp-3025	2238	24	.	.	PUNCT
fnp-3025	2239	1	acta	acta	PROPN
fnp-3025	2239	2	neuropathol	neuropathol	PROPN
fnp-3025	2239	3	,	,	PUNCT
fnp-3025	2239	4	2016	2016	NUM
fnp-3025	2239	5	.	.	PUNCT
fnp-3025	2240	1	132(2	132(2	NUM
fnp-3025	2240	2	):	):	PUNCT
fnp-3025	2240	3	p.	p.	NOUN
fnp-3025	2240	4	313	313	NUM
fnp-3025	2240	5	-	-	SYM
fnp-3025	2240	6	315	315	NUM
fnp-3025	2240	7	.	.	PUNCT
fnp-3025	2240	8	424	424	NUM
fnp-3025	2241	1	.	.	X
fnp-3025	2241	2	irwin	irwin	PROPN
fnp-3025	2241	3	,	,	PUNCT
fnp-3025	2241	4	d.j	d.j	PROPN
fnp-3025	2241	5	.	.	PROPN
fnp-3025	2241	6	,	,	PUNCT
fnp-3025	2241	7	et	et	PROPN
fnp-3025	2241	8	al	al	PROPN
fnp-3025	2241	9	.	.	PROPN
fnp-3025	2241	10	,	,	PUNCT
fnp-3025	2241	11	evaluation	evaluation	NOUN
fnp-3025	2241	12	of	of	ADP
fnp-3025	2241	13	potential	potential	ADJ
fnp-3025	2241	14	infectivity	infectivity	NOUN
fnp-3025	2241	15	of	of	ADP
fnp-3025	2241	16	alzheimer	alzheimer	PROPN
fnp-3025	2241	17	and	and	CCONJ
fnp-3025	2241	18	parkinson	parkinson	NOUN
fnp-3025	2241	19	disease	disease	NOUN
fnp-3025	2241	20	proteins	protein	NOUN
fnp-3025	2241	21	in	in	ADP
fnp-3025	2241	22	recipients	recipient	NOUN
fnp-3025	2241	23	of	of	ADP
fnp-3025	2241	24	cadaver	cadaver	NOUN
fnp-3025	2241	25	-	-	PUNCT
fnp-3025	2241	26	derived	derive	VERB
fnp-3025	2241	27	human	human	ADJ
fnp-3025	2241	28	growth	growth	NOUN
fnp-3025	2241	29	hormone	hormone	NOUN
fnp-3025	2241	30	.	.	PUNCT
fnp-3025	2242	1	jama	jama	PROPN
fnp-3025	2242	2	neurol	neurol	PROPN
fnp-3025	2242	3	,	,	PUNCT
fnp-3025	2242	4	2013	2013	NUM
fnp-3025	2242	5	.	.	PUNCT
fnp-3025	2243	1	70(4	70(4	NUM
fnp-3025	2243	2	):	):	PUNCT
fnp-3025	2243	3	p.	p.	NOUN
fnp-3025	2243	4	462	462	NUM
fnp-3025	2243	5	-	-	SYM
fnp-3025	2243	6	8	8	NUM
fnp-3025	2243	7	.	.	NOUN
fnp-3025	2243	8	425	425	NUM
fnp-3025	2243	9	.	.	PUNCT
fnp-3025	2244	1	kovacs	kovacs	PROPN
fnp-3025	2244	2	,	,	PUNCT
fnp-3025	2244	3	g.g	g.g	PROPN
fnp-3025	2244	4	.	.	PROPN
fnp-3025	2244	5	,	,	PUNCT
fnp-3025	2244	6	et	et	PROPN
fnp-3025	2244	7	al	al	PROPN
fnp-3025	2244	8	.	.	PROPN
fnp-3025	2244	9	,	,	PUNCT
fnp-3025	2244	10	dura	dura	NOUN
fnp-3025	2244	11	mater	mater	NOUN
fnp-3025	2244	12	is	be	AUX
fnp-3025	2244	13	a	a	DET
fnp-3025	2244	14	potential	potential	ADJ
fnp-3025	2244	15	source	source	NOUN
fnp-3025	2244	16	of	of	ADP
fnp-3025	2244	17	abeta	abeta	NOUN
fnp-3025	2244	18	seeds	seed	NOUN
fnp-3025	2244	19	.	.	PUNCT
fnp-3025	2245	1	acta	acta	PROPN
fnp-3025	2245	2	neuropathol	neuropathol	PROPN
fnp-3025	2245	3	,	,	PUNCT
fnp-3025	2245	4	2016	2016	NUM
fnp-3025	2245	5	.	.	PUNCT
fnp-3025	2246	1	131(6	131(6	NUM
fnp-3025	2246	2	):	):	PUNCT
fnp-3025	2246	3	p.	p.	NOUN
fnp-3025	2246	4	911	911	NUM
fnp-3025	2246	5	-	-	SYM
fnp-3025	2246	6	23	23	NUM
fnp-3025	2246	7	.	.	PUNCT
fnp-3025	2247	1	426	426	NUM
fnp-3025	2247	2	.	.	PUNCT
fnp-3025	2247	3	duyckaerts	duyckaert	NOUN
fnp-3025	2247	4	,	,	PUNCT
fnp-3025	2247	5	c.	c.	PROPN
fnp-3025	2247	6	,	,	PUNCT
fnp-3025	2247	7	et	et	PROPN
fnp-3025	2247	8	al	al	PROPN
fnp-3025	2247	9	.	.	PROPN
fnp-3025	2247	10	,	,	PUNCT
fnp-3025	2247	11	neuropathology	neuropathology	NOUN
fnp-3025	2247	12	of	of	ADP
fnp-3025	2247	13	iatrogenic	iatrogenic	ADJ
fnp-3025	2247	14	creutzfeldt	creutzfeldt	ADJ
fnp-3025	2247	15	-	-	PUNCT
fnp-3025	2247	16	jakob	jakob	ADJ
fnp-3025	2247	17	disease	disease	NOUN
fnp-3025	2247	18	and	and	CCONJ
fnp-3025	2247	19	immunoassay	immunoassay	PROPN
fnp-3025	2247	20	of	of	ADP
fnp-3025	2247	21	french	french	ADJ
fnp-3025	2247	22	cadaver	cadaver	NOUN
fnp-3025	2247	23	-	-	PUNCT
fnp-3025	2247	24	sourced	source	VERB
fnp-3025	2247	25	growth	growth	NOUN
fnp-3025	2247	26	hormone	hormone	NOUN
fnp-3025	2247	27	batches	batch	NOUN
fnp-3025	2247	28	suggest	suggest	VERB
fnp-3025	2247	29	possible	possible	ADJ
fnp-3025	2247	30	transmission	transmission	NOUN
fnp-3025	2247	31	of	of	ADP
fnp-3025	2247	32	tauopathy	tauopathy	NOUN
fnp-3025	2247	33	and	and	CCONJ
fnp-3025	2247	34	long	long	ADJ
fnp-3025	2247	35	incubation	incubation	NOUN
fnp-3025	2247	36	periods	period	NOUN
fnp-3025	2247	37	for	for	ADP
fnp-3025	2247	38	the	the	DET
fnp-3025	2247	39	transmission	transmission	NOUN
fnp-3025	2247	40	of	of	ADP
fnp-3025	2247	41	abeta	abeta	PROPN
fnp-3025	2247	42	pathology	pathology	PROPN
fnp-3025	2247	43	.	.	PUNCT
fnp-3025	2248	1	acta	acta	PROPN
fnp-3025	2248	2	neuropathol	neuropathol	PROPN
fnp-3025	2248	3	,	,	PUNCT
fnp-3025	2248	4	2018	2018	NUM
fnp-3025	2248	5	.	.	PUNCT
fnp-3025	2249	1	135(2	135(2	NUM
fnp-3025	2249	2	):	):	PUNCT
fnp-3025	2249	3	p.	p.	NOUN
fnp-3025	2249	4	201	201	NUM
fnp-3025	2249	5	-	-	SYM
fnp-3025	2249	6	212	212	NUM
fnp-3025	2249	7	.	.	PUNCT
fnp-3025	2250	1	427	427	NUM
fnp-3025	2250	2	.	.	PUNCT
fnp-3025	2251	1	purro	purro	PROPN
fnp-3025	2251	2	,	,	PUNCT
fnp-3025	2251	3	s.a	s.a	PROPN
fnp-3025	2251	4	.	.	PROPN
fnp-3025	2251	5	,	,	PUNCT
fnp-3025	2251	6	et	et	PROPN
fnp-3025	2251	7	al	al	PROPN
fnp-3025	2251	8	.	.	PROPN
fnp-3025	2251	9	,	,	PUNCT
fnp-3025	2251	10	transmission	transmission	NOUN
fnp-3025	2251	11	of	of	ADP
fnp-3025	2251	12	amyloid	amyloid	NOUN
fnp-3025	2251	13	-	-	PUNCT
fnp-3025	2251	14	beta	beta	NOUN
fnp-3025	2251	15	protein	protein	NOUN
fnp-3025	2251	16	pathology	pathology	NOUN
fnp-3025	2251	17	from	from	ADP
fnp-3025	2251	18	cadaveric	cadaveric	ADJ
fnp-3025	2251	19	pituitary	pituitary	ADJ
fnp-3025	2251	20	growth	growth	NOUN
fnp-3025	2251	21	hormone	hormone	NOUN
fnp-3025	2251	22	.	.	PUNCT
fnp-3025	2252	1	nature	nature	NOUN
fnp-3025	2252	2	,	,	PUNCT
fnp-3025	2252	3	2018	2018	NUM
fnp-3025	2252	4	.	.	PUNCT
fnp-3025	2253	1	564(7736	564(7736	NUM
fnp-3025	2253	2	):	):	PUNCT
fnp-3025	2253	3	p.	p.	NOUN
fnp-3025	2253	4	415	415	NUM
fnp-3025	2253	5	-	-	SYM
fnp-3025	2253	6	419	419	NUM
fnp-3025	2253	7	.	.	PUNCT
fnp-3025	2254	1	428	428	NUM
fnp-3025	2254	2	.	.	PUNCT
fnp-3025	2254	3	nakayama	nakayama	PROPN
fnp-3025	2254	4	,	,	PUNCT
fnp-3025	2254	5	h.	h.	PROPN
fnp-3025	2254	6	,	,	PUNCT
fnp-3025	2254	7	et	et	PROPN
fnp-3025	2254	8	al	al	PROPN
fnp-3025	2254	9	.	.	PROPN
fnp-3025	2254	10	,	,	PUNCT
fnp-3025	2254	11	cerebral	cerebral	ADJ
fnp-3025	2254	12	amyloid	amyloid	NOUN
fnp-3025	2254	13	angiopathy	angiopathy	NOUN
fnp-3025	2254	14	in	in	ADP
fnp-3025	2254	15	an	an	DET
fnp-3025	2254	16	aged	aged	ADJ
fnp-3025	2254	17	great	great	ADJ
fnp-3025	2254	18	spotted	spot	VERB
fnp-3025	2254	19	woodpecker	woodpecker	NOUN
fnp-3025	2254	20	(	(	PUNCT
fnp-3025	2254	21	picoides	picoide	VERB
fnp-3025	2254	22	major	major	ADJ
fnp-3025	2254	23	)	)	PUNCT
fnp-3025	2254	24	.	.	PUNCT
fnp-3025	2255	1	neurobiol	neurobiol	PROPN
fnp-3025	2255	2	aging	aging	NOUN
fnp-3025	2255	3	,	,	PUNCT
fnp-3025	2255	4	1999	1999	NUM
fnp-3025	2255	5	.	.	PUNCT
fnp-3025	2256	1	20(1	20(1	NUM
fnp-3025	2256	2	):	):	PUNCT
fnp-3025	2256	3	p.	p.	NOUN
fnp-3025	2256	4	53	53	NUM
fnp-3025	2256	5	-	-	SYM
fnp-3025	2256	6	6	6	NUM
fnp-3025	2256	7	.	.	NOUN
fnp-3025	2256	8	429	429	NUM
fnp-3025	2256	9	.	.	PUNCT
fnp-3025	2257	1	cork	cork	NOUN
fnp-3025	2257	2	,	,	PUNCT
fnp-3025	2257	3	l.c	l.c	PROPN
fnp-3025	2257	4	.	.	PROPN
fnp-3025	2257	5	,	,	PUNCT
fnp-3025	2257	6	et	et	PROPN
fnp-3025	2257	7	al	al	PROPN
fnp-3025	2257	8	.	.	PROPN
fnp-3025	2257	9	,	,	PUNCT
fnp-3025	2257	10	neurofibrillary	neurofibrillary	ADJ
fnp-3025	2257	11	tangles	tangle	NOUN
fnp-3025	2257	12	and	and	CCONJ
fnp-3025	2257	13	senile	senile	ADJ
fnp-3025	2257	14	plaques	plaque	NOUN
fnp-3025	2257	15	in	in	ADP
fnp-3025	2257	16	aged	aged	ADJ
fnp-3025	2257	17	bears	bear	NOUN
fnp-3025	2257	18	.	.	PUNCT
fnp-3025	2258	1	j	j	PROPN
fnp-3025	2258	2	neuropathol	neuropathol	PROPN
fnp-3025	2258	3	exp	exp	PROPN
fnp-3025	2258	4	neurol	neurol	PROPN
fnp-3025	2258	5	,	,	PUNCT
fnp-3025	2258	6	1988	1988	NUM
fnp-3025	2258	7	.	.	PUNCT
fnp-3025	2259	1	47(6	47(6	NUM
fnp-3025	2259	2	):	):	PUNCT
fnp-3025	2259	3	p.	p.	NOUN
fnp-3025	2259	4	629	629	NUM
fnp-3025	2259	5	-	-	SYM
fnp-3025	2259	6	41	41	NUM
fnp-3025	2259	7	.	.	PUNCT
fnp-3025	2259	8	430	430	NUM
fnp-3025	2259	9	.	.	PUNCT
fnp-3025	2260	1	tekirian	tekirian	ADJ
fnp-3025	2260	2	,	,	PUNCT
fnp-3025	2260	3	t.l	t.l	PROPN
fnp-3025	2260	4	.	.	PROPN
fnp-3025	2260	5	,	,	PUNCT
fnp-3025	2260	6	et	et	PROPN
fnp-3025	2260	7	al	al	PROPN
fnp-3025	2260	8	.	.	PROPN
fnp-3025	2260	9	,	,	PUNCT
fnp-3025	2260	10	carboxy	carboxy	PROPN
fnp-3025	2260	11	terminal	terminal	NOUN
fnp-3025	2260	12	of	of	ADP
fnp-3025	2260	13	beta	beta	NOUN
fnp-3025	2260	14	-	-	PUNCT
fnp-3025	2260	15	amyloid	amyloid	NOUN
fnp-3025	2260	16	deposits	deposit	NOUN
fnp-3025	2260	17	in	in	ADP
fnp-3025	2260	18	aged	aged	ADJ
fnp-3025	2260	19	human	human	NOUN
fnp-3025	2260	20	,	,	PUNCT
fnp-3025	2260	21	canine	canine	NOUN
fnp-3025	2260	22	,	,	PUNCT
fnp-3025	2260	23	and	and	CCONJ
fnp-3025	2260	24	polar	polar	ADJ
fnp-3025	2260	25	bear	bear	NOUN
fnp-3025	2260	26	brains	brain	NOUN
fnp-3025	2260	27	.	.	PUNCT
fnp-3025	2261	1	neurobiol	neurobiol	PROPN
fnp-3025	2261	2	aging	aging	NOUN
fnp-3025	2261	3	,	,	PUNCT
fnp-3025	2261	4	1996	1996	NUM
fnp-3025	2261	5	.	.	PUNCT
fnp-3025	2262	1	17(2	17(2	NUM
fnp-3025	2262	2	):	):	PUNCT
fnp-3025	2262	3	p.	p.	NOUN
fnp-3025	2262	4	249	249	NUM
fnp-3025	2262	5	-	-	SYM
fnp-3025	2262	6	57	57	NUM
fnp-3025	2262	7	.	.	PUNCT
fnp-3025	2263	1	431	431	NUM
fnp-3025	2263	2	.	.	PUNCT
fnp-3025	2264	1	uchida	uchida	PROPN
fnp-3025	2264	2	,	,	PUNCT
fnp-3025	2264	3	k.	k.	PROPN
fnp-3025	2264	4	,	,	PUNCT
fnp-3025	2264	5	et	et	PROPN
fnp-3025	2264	6	al	al	PROPN
fnp-3025	2264	7	.	.	PROPN
fnp-3025	2264	8	,	,	PUNCT
fnp-3025	2264	9	senile	senile	ADJ
fnp-3025	2264	10	plaques	plaque	NOUN
fnp-3025	2264	11	and	and	CCONJ
fnp-3025	2264	12	other	other	ADJ
fnp-3025	2264	13	senile	senile	ADJ
fnp-3025	2264	14	changes	change	NOUN
fnp-3025	2264	15	in	in	ADP
fnp-3025	2264	16	the	the	DET
fnp-3025	2264	17	brain	brain	NOUN
fnp-3025	2264	18	of	of	ADP
fnp-3025	2264	19	an	an	DET
fnp-3025	2264	20	aged	aged	ADJ
fnp-3025	2264	21	american	american	ADJ
fnp-3025	2264	22	black	black	ADJ
fnp-3025	2264	23	bear	bear	NOUN
fnp-3025	2264	24	.	.	PUNCT
fnp-3025	2265	1	vet	vet	NOUN
fnp-3025	2265	2	pathol	pathol	NOUN
fnp-3025	2265	3	,	,	PUNCT
fnp-3025	2265	4	1995	1995	NUM
fnp-3025	2265	5	.	.	PUNCT
fnp-3025	2266	1	32(4	32(4	NUM
fnp-3025	2266	2	):	):	PUNCT
fnp-3025	2266	3	p.	p.	NOUN
fnp-3025	2266	4	412	412	NUM
fnp-3025	2266	5	-	-	SYM
fnp-3025	2266	6	4	4	NUM
fnp-3025	2266	7	.	.	NOUN
fnp-3025	2266	8	432	432	NUM
fnp-3025	2266	9	.	.	PUNCT
fnp-3025	2267	1	cummings	cummings	PROPN
fnp-3025	2267	2	,	,	PUNCT
fnp-3025	2267	3	b.j	b.j	PROPN
fnp-3025	2267	4	.	.	PROPN
fnp-3025	2267	5	,	,	PUNCT
fnp-3025	2267	6	et	et	PROPN
fnp-3025	2267	7	al	al	PROPN
fnp-3025	2267	8	.	.	PROPN
fnp-3025	2267	9	,	,	PUNCT
fnp-3025	2267	10	beta	beta	NOUN
fnp-3025	2267	11	-	-	PUNCT
fnp-3025	2267	12	amyloid	amyloid	NOUN
fnp-3025	2267	13	accumulation	accumulation	NOUN
fnp-3025	2267	14	correlates	correlate	VERB
fnp-3025	2267	15	with	with	ADP
fnp-3025	2267	16	cognitive	cognitive	ADJ
fnp-3025	2267	17	dysfunction	dysfunction	NOUN
fnp-3025	2267	18	in	in	ADP
fnp-3025	2267	19	the	the	DET
fnp-3025	2267	20	aged	aged	ADJ
fnp-3025	2267	21	canine	canine	NOUN
fnp-3025	2267	22	.	.	PUNCT
fnp-3025	2268	1	neurobiol	neurobiol	PROPN
fnp-3025	2268	2	learn	learn	VERB
fnp-3025	2268	3	mem	mem	ADJ
fnp-3025	2268	4	,	,	PUNCT
fnp-3025	2268	5	1996	1996	NUM
fnp-3025	2268	6	.	.	PUNCT
fnp-3025	2269	1	66(1	66(1	X
fnp-3025	2269	2	):	):	PUNCT
fnp-3025	2269	3	p.	p.	NOUN
fnp-3025	2269	4	11	11	NUM
fnp-3025	2269	5	-	-	SYM
fnp-3025	2269	6	23	23	NUM
fnp-3025	2269	7	.	.	PUNCT
fnp-3025	2270	1	433	433	NUM
fnp-3025	2270	2	.	.	PUNCT
fnp-3025	2271	1	ishihara	ishihara	PROPN
fnp-3025	2271	2	,	,	PUNCT
fnp-3025	2271	3	t.	t.	PROPN
fnp-3025	2271	4	,	,	PUNCT
fnp-3025	2271	5	et	et	PROPN
fnp-3025	2271	6	al	al	PROPN
fnp-3025	2271	7	.	.	PROPN
fnp-3025	2271	8	,	,	PUNCT
fnp-3025	2271	9	immunohistochemical	immunohistochemical	ADJ
fnp-3025	2271	10	and	and	CCONJ
fnp-3025	2271	11	immunoelectron	immunoelectron	ADJ
fnp-3025	2271	12	microscopical	microscopical	ADJ
fnp-3025	2271	13	characterization	characterization	NOUN
fnp-3025	2271	14	of	of	ADP
fnp-3025	2271	15	cerebrovascular	cerebrovascular	ADJ
fnp-3025	2271	16	and	and	CCONJ
fnp-3025	2271	17	senile	senile	ADJ
fnp-3025	2271	18	plaque	plaque	NOUN
fnp-3025	2271	19	amyloid	amyloid	NOUN
fnp-3025	2271	20	in	in	ADP
fnp-3025	2271	21	aged	aged	ADJ
fnp-3025	2271	22	dogs	dog	NOUN
fnp-3025	2271	23	’	'	PUNCT
fnp-3025	2271	24	brains	brain	NOUN
fnp-3025	2271	25	.	.	PUNCT
fnp-3025	2272	1	brain	brain	NOUN
fnp-3025	2272	2	res	re	NOUN
fnp-3025	2272	3	,	,	PUNCT
fnp-3025	2272	4	1991	1991	NUM
fnp-3025	2272	5	.	.	PUNCT
fnp-3025	2273	1	548(1	548(1	NUM
fnp-3025	2273	2	-	-	SYM
fnp-3025	2273	3	2	2	NUM
fnp-3025	2273	4	):	):	PUNCT
fnp-3025	2273	5	p.	p.	NOUN
fnp-3025	2273	6	196	196	NUM
fnp-3025	2273	7	-	-	SYM
fnp-3025	2273	8	205	205	NUM
fnp-3025	2273	9	.	.	PUNCT
fnp-3025	2274	1	434	434	NUM
fnp-3025	2274	2	.	.	PUNCT
fnp-3025	2275	1	uchida	uchida	PROPN
fnp-3025	2275	2	,	,	PUNCT
fnp-3025	2275	3	k.	k.	PROPN
fnp-3025	2275	4	,	,	PUNCT
fnp-3025	2275	5	et	et	PROPN
fnp-3025	2275	6	al	al	PROPN
fnp-3025	2275	7	.	.	PROPN
fnp-3025	2275	8	,	,	PUNCT
fnp-3025	2275	9	immunohistochemical	immunohistochemical	ADJ
fnp-3025	2275	10	analysis	analysis	NOUN
fnp-3025	2275	11	of	of	ADP
fnp-3025	2275	12	constituents	constituent	NOUN
fnp-3025	2275	13	of	of	ADP
fnp-3025	2275	14	senile	senile	ADJ
fnp-3025	2275	15	plaques	plaque	NOUN
fnp-3025	2275	16	and	and	CCONJ
fnp-3025	2275	17	cerebro	cerebro	NOUN
fnp-3025	2275	18	-	-	PUNCT
fnp-3025	2275	19	vascular	vascular	ADJ
fnp-3025	2275	20	amyloid	amyloid	NOUN
fnp-3025	2275	21	in	in	ADP
fnp-3025	2275	22	aged	aged	ADJ
fnp-3025	2275	23	dogs	dog	NOUN
fnp-3025	2275	24	.	.	PUNCT
fnp-3025	2276	1	j	j	PROPN
fnp-3025	2276	2	vet	vet	PROPN
fnp-3025	2276	3	med	med	PROPN
fnp-3025	2276	4	sci	sci	PROPN
fnp-3025	2276	5	,	,	PUNCT
fnp-3025	2276	6	1992	1992	NUM
fnp-3025	2276	7	.	.	PUNCT
fnp-3025	2277	1	54(5	54(5	NUM
fnp-3025	2277	2	):	):	PUNCT
fnp-3025	2278	1	p.	p.	NOUN
fnp-3025	2278	2	1023	1023	NUM
fnp-3025	2278	3	-	-	SYM
fnp-3025	2278	4	9	9	NUM
fnp-3025	2278	5	.	.	NUM
fnp-3025	2278	6	435	435	NUM
fnp-3025	2278	7	.	.	PUNCT
fnp-3025	2279	1	zeiss	zeiss	PROPN
fnp-3025	2279	2	,	,	PUNCT
fnp-3025	2279	3	c.j	c.j	PROPN
fnp-3025	2279	4	.	.	PROPN
fnp-3025	2279	5	,	,	PUNCT
fnp-3025	2279	6	utility	utility	NOUN
fnp-3025	2279	7	of	of	ADP
fnp-3025	2279	8	spontaneous	spontaneous	ADJ
fnp-3025	2279	9	animal	animal	NOUN
fnp-3025	2279	10	models	model	NOUN
fnp-3025	2279	11	of	of	ADP
fnp-3025	2279	12	alzheimer	alzheimer	PROPN
fnp-3025	2279	13	’s	’s	PART
fnp-3025	2279	14	disease	disease	NOUN
fnp-3025	2279	15	in	in	ADP
fnp-3025	2279	16	preclinical	preclinical	ADJ
fnp-3025	2279	17	efficacy	efficacy	NOUN
fnp-3025	2279	18	studies	study	NOUN
fnp-3025	2279	19	.	.	PUNCT
fnp-3025	2280	1	cell	cell	NOUN
fnp-3025	2280	2	tissue	tissue	NOUN
fnp-3025	2280	3	res	re	NOUN
fnp-3025	2280	4	,	,	PUNCT
fnp-3025	2280	5	2020	2020	NUM
fnp-3025	2280	6	.	.	PUNCT
fnp-3025	2281	1	380(2	380(2	NUM
fnp-3025	2281	2	):	):	PUNCT
fnp-3025	2282	1	p.	p.	NOUN
fnp-3025	2282	2	273	273	NUM
fnp-3025	2282	3	-	-	SYM
fnp-3025	2282	4	286	286	NUM
fnp-3025	2282	5	.	.	PUNCT
fnp-3025	2282	6	436	436	NUM
fnp-3025	2282	7	.	.	PUNCT
fnp-3025	2283	1	nakamura	nakamura	PROPN
fnp-3025	2283	2	,	,	PUNCT
fnp-3025	2283	3	s.	s.	PROPN
fnp-3025	2283	4	,	,	PUNCT
fnp-3025	2283	5	et	et	PROPN
fnp-3025	2283	6	al	al	PROPN
fnp-3025	2283	7	.	.	PROPN
fnp-3025	2283	8	,	,	PUNCT
fnp-3025	2283	9	senile	senile	ADJ
fnp-3025	2283	10	plaques	plaque	NOUN
fnp-3025	2283	11	in	in	ADP
fnp-3025	2283	12	very	very	ADV
fnp-3025	2283	13	aged	aged	ADJ
fnp-3025	2283	14	cats	cat	NOUN
fnp-3025	2283	15	.	.	PUNCT
fnp-3025	2284	1	acta	acta	PROPN
fnp-3025	2284	2	neuropathol	neuropathol	PROPN
fnp-3025	2284	3	,	,	PUNCT
fnp-3025	2284	4	1996	1996	NUM
fnp-3025	2284	5	.	.	PUNCT
fnp-3025	2285	1	91(4	91(4	NUM
fnp-3025	2285	2	):	):	PUNCT
fnp-3025	2285	3	p.	p.	NOUN
fnp-3025	2285	4	437	437	NUM
fnp-3025	2285	5	-	-	SYM
fnp-3025	2285	6	9	9	NUM
fnp-3025	2285	7	.	.	NUM
fnp-3025	2285	8	437	437	NUM
fnp-3025	2286	1	.	.	PUNCT
fnp-3025	2286	2	nakamura	nakamura	PROPN
fnp-3025	2286	3	,	,	PUNCT
fnp-3025	2286	4	s.	s.	PROPN
fnp-3025	2286	5	,	,	PUNCT
fnp-3025	2286	6	et	et	PROPN
fnp-3025	2286	7	al	al	PROPN
fnp-3025	2286	8	.	.	PROPN
fnp-3025	2286	9	,	,	PUNCT
fnp-3025	2286	10	senile	senile	ADJ
fnp-3025	2286	11	plaques	plaque	NOUN
fnp-3025	2286	12	in	in	ADP
fnp-3025	2286	13	an	an	DET
fnp-3025	2286	14	aged	aged	ADJ
fnp-3025	2286	15	two	two	NUM
fnp-3025	2286	16	-	-	PUNCT
fnp-3025	2286	17	humped	humped	NOUN
fnp-3025	2286	18	(	(	PUNCT
fnp-3025	2286	19	bactrian	bactrian	ADJ
fnp-3025	2286	20	)	)	PUNCT
fnp-3025	2286	21	camel	camel	NOUN
fnp-3025	2286	22	(	(	PUNCT
fnp-3025	2286	23	camelus	camelus	ADJ
fnp-3025	2286	24	bactrianus	bactrianus	NOUN
fnp-3025	2286	25	)	)	PUNCT
fnp-3025	2286	26	.	.	PUNCT
fnp-3025	2287	1	acta	acta	PROPN
fnp-3025	2287	2	neuropathol	neuropathol	PROPN
fnp-3025	2287	3	,	,	PUNCT
fnp-3025	2287	4	1995	1995	NUM
fnp-3025	2287	5	.	.	PUNCT
fnp-3025	2288	1	90(4	90(4	NUM
fnp-3025	2288	2	):	):	PUNCT
fnp-3025	2288	3	p.	p.	NOUN
fnp-3025	2288	4	415	415	NUM
fnp-3025	2288	5	-	-	SYM
fnp-3025	2288	6	8	8	NUM
fnp-3025	2288	7	.	.	X
fnp-3025	2289	1	438	438	NUM
fnp-3025	2289	2	.	.	PUNCT
fnp-3025	2290	1	roertgen	roertgen	PROPN
fnp-3025	2290	2	,	,	PUNCT
fnp-3025	2290	3	k.e	k.e	PROPN
fnp-3025	2290	4	.	.	PROPN
fnp-3025	2290	5	,	,	PUNCT
fnp-3025	2290	6	et	et	PROPN
fnp-3025	2290	7	al	al	PROPN
fnp-3025	2290	8	.	.	PROPN
fnp-3025	2290	9	,	,	PUNCT
fnp-3025	2290	10	a	a	DET
fnp-3025	2290	11	beta	beta	NOUN
fnp-3025	2290	12	-	-	PUNCT
fnp-3025	2290	13	associated	associate	VERB
fnp-3025	2290	14	cerebral	cerebral	ADJ
fnp-3025	2290	15	angiopathy	angiopathy	ADJ
fnp-3025	2290	16	and	and	CCONJ
fnp-3025	2290	17	senile	senile	ADJ
fnp-3025	2290	18	plaques	plaque	NOUN
fnp-3025	2290	19	with	with	ADP
fnp-3025	2290	20	neurofibrillary	neurofibrillary	ADJ
fnp-3025	2290	21	tangles	tangle	NOUN
fnp-3025	2290	22	and	and	CCONJ
fnp-3025	2290	23	cerebral	cerebral	ADJ
fnp-3025	2290	24	hemorrhage	hemorrhage	NOUN
fnp-3025	2290	25	in	in	ADP
fnp-3025	2290	26	an	an	DET
fnp-3025	2290	27	aged	aged	ADJ
fnp-3025	2290	28	wolverine	wolverine	NOUN
fnp-3025	2290	29	(	(	PUNCT
fnp-3025	2290	30	gulo	gulo	PROPN
fnp-3025	2290	31	gulo	gulo	PROPN
fnp-3025	2290	32	)	)	PUNCT
fnp-3025	2290	33	.	.	PUNCT
fnp-3025	2291	1	neurobiol	neurobiol	PROPN
fnp-3025	2291	2	aging	aging	NOUN
fnp-3025	2291	3	,	,	PUNCT
fnp-3025	2291	4	1996	1996	NUM
fnp-3025	2291	5	.	.	PUNCT
fnp-3025	2292	1	17(2	17(2	NUM
fnp-3025	2292	2	):	):	PUNCT
fnp-3025	2292	3	p.	p.	NOUN
fnp-3025	2292	4	243	243	NUM
fnp-3025	2292	5	-	-	SYM
fnp-3025	2292	6	7	7	NUM
fnp-3025	2292	7	.	.	NUM
fnp-3025	2292	8	439	439	NUM
fnp-3025	2292	9	.	.	PUNCT
fnp-3025	2293	1	heuer	heuer	PROPN
fnp-3025	2293	2	,	,	PUNCT
fnp-3025	2293	3	e.	e.	PROPN
fnp-3025	2293	4	,	,	PUNCT
fnp-3025	2293	5	et	et	PROPN
fnp-3025	2293	6	al	al	PROPN
fnp-3025	2293	7	.	.	PROPN
fnp-3025	2293	8	,	,	PUNCT
fnp-3025	2293	9	nonhuman	nonhuman	ADJ
fnp-3025	2293	10	primate	primate	NOUN
fnp-3025	2293	11	models	model	NOUN
fnp-3025	2293	12	of	of	ADP
fnp-3025	2293	13	alzheimer	alzheimer	PROPN
fnp-3025	2293	14	-	-	PUNCT
fnp-3025	2293	15	like	like	ADJ
fnp-3025	2293	16	cerebral	cerebral	ADJ
fnp-3025	2293	17	proteopathy	proteopathy	ADJ
fnp-3025	2293	18	.	.	PUNCT
fnp-3025	2294	1	curr	curr	PROPN
fnp-3025	2294	2	pharm	pharm	PROPN
fnp-3025	2294	3	des	des	PROPN
fnp-3025	2294	4	,	,	PUNCT
fnp-3025	2294	5	2012	2012	NUM
fnp-3025	2294	6	.	.	PUNCT
fnp-3025	2295	1	18(8	18(8	NUM
fnp-3025	2295	2	):	):	PUNCT
fnp-3025	2295	3	p.	p.	NOUN
fnp-3025	2295	4	1159	1159	NUM
fnp-3025	2295	5	-	-	SYM
fnp-3025	2295	6	69	69	NUM
fnp-3025	2295	7	.	.	PUNCT
fnp-3025	2296	1	440	440	NUM
fnp-3025	2296	2	.	.	PUNCT
fnp-3025	2297	1	jankowsky	jankowsky	PROPN
fnp-3025	2297	2	,	,	PUNCT
fnp-3025	2297	3	j.l	j.l	PROPN
fnp-3025	2297	4	.	.	PROPN
fnp-3025	2297	5	,	,	PUNCT
fnp-3025	2297	6	et	et	PROPN
fnp-3025	2297	7	al	al	PROPN
fnp-3025	2297	8	.	.	PROPN
fnp-3025	2297	9	,	,	PUNCT
fnp-3025	2297	10	rodent	rodent	VERB
fnp-3025	2297	11	a	a	DET
fnp-3025	2297	12	beta	beta	NOUN
fnp-3025	2297	13	modulates	modulate	NOUN
fnp-3025	2297	14	the	the	DET
fnp-3025	2297	15	solubility	solubility	NOUN
fnp-3025	2297	16	and	and	CCONJ
fnp-3025	2297	17	distribution	distribution	NOUN
fnp-3025	2297	18	of	of	ADP
fnp-3025	2297	19	amyloid	amyloid	NOUN
fnp-3025	2297	20	deposits	deposit	NOUN
fnp-3025	2297	21	in	in	ADP
fnp-3025	2297	22	transgenic	transgenic	NOUN
fnp-3025	2297	23	mice	mouse	NOUN
fnp-3025	2297	24	.	.	PUNCT
fnp-3025	2298	1	j	j	PROPN
fnp-3025	2298	2	biol	biol	PROPN
fnp-3025	2298	3	chem	chem	NOUN
fnp-3025	2298	4	,	,	PUNCT
fnp-3025	2298	5	2007	2007	NUM
fnp-3025	2298	6	.	.	PUNCT
fnp-3025	2299	1	282(31	282(31	NUM
fnp-3025	2299	2	):	):	PUNCT
fnp-3025	2299	3	p.	p.	NOUN
fnp-3025	2299	4	22707	22707	NUM
fnp-3025	2299	5	-	-	SYM
fnp-3025	2299	6	20	20	NUM
fnp-3025	2299	7	.	.	PUNCT
fnp-3025	2300	1	441	441	NUM
fnp-3025	2300	2	.	.	X
fnp-3025	2300	3	steffen	steffen	PROPN
fnp-3025	2300	4	,	,	PUNCT
fnp-3025	2300	5	j.	j.	PROPN
fnp-3025	2300	6	,	,	PUNCT
fnp-3025	2300	7	et	et	PROPN
fnp-3025	2300	8	al	al	PROPN
fnp-3025	2300	9	.	.	PROPN
fnp-3025	2300	10	,	,	PUNCT
fnp-3025	2300	11	expression	expression	NOUN
fnp-3025	2300	12	of	of	ADP
fnp-3025	2300	13	endogenous	endogenous	ADJ
fnp-3025	2300	14	mouse	mouse	NOUN
fnp-3025	2300	15	app	app	NOUN
fnp-3025	2300	16	modulates	modulate	VERB
fnp-3025	2300	17	beta	beta	NOUN
fnp-3025	2300	18	-	-	PUNCT
fnp-3025	2300	19	amyloid	amyloid	NOUN
fnp-3025	2300	20	deposition	deposition	NOUN
fnp-3025	2300	21	in	in	ADP
fnp-3025	2300	22	happ	happ	NOUN
fnp-3025	2300	23	-	-	PUNCT
fnp-3025	2300	24	transgenic	transgenic	NOUN
fnp-3025	2300	25	mice	mouse	NOUN
fnp-3025	2300	26	.	.	PUNCT
fnp-3025	2301	1	acta	acta	PROPN
fnp-3025	2301	2	neuropathol	neuropathol	PROPN
fnp-3025	2301	3	commun	commun	PROPN
fnp-3025	2301	4	,	,	PUNCT
fnp-3025	2301	5	2017	2017	NUM
fnp-3025	2301	6	.	.	PUNCT
fnp-3025	2302	1	5(1	5(1	NUM
fnp-3025	2302	2	):	):	PUNCT
fnp-3025	2302	3	p.	p.	NOUN
fnp-3025	2302	4	49	49	NUM
fnp-3025	2302	5	.	.	PUNCT
fnp-3025	2303	1	442	442	NUM
fnp-3025	2303	2	.	.	PUNCT
fnp-3025	2303	3	price	price	NOUN
fnp-3025	2303	4	,	,	PUNCT
fnp-3025	2303	5	d.l	d.l	PROPN
fnp-3025	2303	6	.	.	PROPN
fnp-3025	2303	7	,	,	PUNCT
fnp-3025	2303	8	et	et	PROPN
fnp-3025	2303	9	al	al	PROPN
fnp-3025	2303	10	.	.	PROPN
fnp-3025	2303	11	,	,	PUNCT
fnp-3025	2303	12	aged	aged	ADJ
fnp-3025	2303	13	non	non	ADJ
fnp-3025	2303	14	-	-	ADJ
fnp-3025	2303	15	human	human	ADJ
fnp-3025	2303	16	primates	primate	NOUN
fnp-3025	2303	17	:	:	PUNCT
fnp-3025	2303	18	an	an	DET
fnp-3025	2303	19	animal	animal	NOUN
fnp-3025	2303	20	model	model	NOUN
fnp-3025	2303	21	of	of	ADP
fnp-3025	2303	22	age	age	NOUN
fnp-3025	2303	23	-	-	PUNCT
fnp-3025	2303	24	associated	associate	VERB
fnp-3025	2303	25	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2303	26	disease	disease	NOUN
fnp-3025	2303	27	.	.	PUNCT
fnp-3025	2304	1	brain	brain	NOUN
fnp-3025	2304	2	pathol	pathol	NOUN
fnp-3025	2304	3	,	,	PUNCT
fnp-3025	2304	4	1991	1991	NUM
fnp-3025	2304	5	.	.	PUNCT
fnp-3025	2305	1	1(4	1(4	NUM
fnp-3025	2305	2	):	):	PUNCT
fnp-3025	2305	3	p.	p.	NOUN
fnp-3025	2305	4	287	287	NUM
fnp-3025	2305	5	-	-	SYM
fnp-3025	2305	6	96	96	NUM
fnp-3025	2305	7	.	.	PUNCT
fnp-3025	2306	1	443	443	NUM
fnp-3025	2306	2	.	.	PUNCT
fnp-3025	2307	1	selkoe	selkoe	PROPN
fnp-3025	2307	2	,	,	PUNCT
fnp-3025	2307	3	d.j	d.j	PROPN
fnp-3025	2307	4	.	.	PROPN
fnp-3025	2307	5	,	,	PUNCT
fnp-3025	2307	6	et	et	PROPN
fnp-3025	2307	7	al	al	PROPN
fnp-3025	2307	8	.	.	PROPN
fnp-3025	2307	9	,	,	PUNCT
fnp-3025	2307	10	conservation	conservation	NOUN
fnp-3025	2307	11	of	of	ADP
fnp-3025	2307	12	brain	brain	NOUN
fnp-3025	2307	13	amyloid	amyloid	NOUN
fnp-3025	2307	14	proteins	protein	NOUN
fnp-3025	2307	15	in	in	ADP
fnp-3025	2307	16	aged	aged	ADJ
fnp-3025	2307	17	mammals	mammal	NOUN
fnp-3025	2307	18	and	and	CCONJ
fnp-3025	2307	19	humans	human	NOUN
fnp-3025	2307	20	with	with	ADP
fnp-3025	2307	21	alzheimer	alzheimer	PROPN
fnp-3025	2307	22	’s	’s	PART
fnp-3025	2307	23	disease	disease	NOUN
fnp-3025	2307	24	.	.	PUNCT
fnp-3025	2308	1	science	science	NOUN
fnp-3025	2308	2	,	,	PUNCT
fnp-3025	2308	3	1987	1987	NUM
fnp-3025	2308	4	.	.	PUNCT
fnp-3025	2309	1	235(4791	235(4791	X
fnp-3025	2309	2	):	):	PUNCT
fnp-3025	2309	3	p.	p.	NOUN
fnp-3025	2309	4	873	873	NUM
fnp-3025	2309	5	-	-	SYM
fnp-3025	2309	6	7	7	NUM
fnp-3025	2309	7	.	.	NOUN
fnp-3025	2309	8	444	444	NUM
fnp-3025	2309	9	.	.	X
fnp-3025	2310	1	walker	walker	PROPN
fnp-3025	2310	2	,	,	PUNCT
fnp-3025	2310	3	l.c	l.c	PROPN
fnp-3025	2310	4	.	.	PROPN
fnp-3025	2310	5	and	and	CCONJ
fnp-3025	2310	6	l.c	l.c	PROPN
fnp-3025	2310	7	.	.	PROPN
fnp-3025	2310	8	cork	cork	PROPN
fnp-3025	2310	9	,	,	PUNCT
fnp-3025	2310	10	the	the	DET
fnp-3025	2310	11	neurobiology	neurobiology	NOUN
fnp-3025	2310	12	of	of	ADP
fnp-3025	2310	13	aging	aging	NOUN
fnp-3025	2310	14	in	in	ADP
fnp-3025	2310	15	nonhuman	nonhuman	ADJ
fnp-3025	2310	16	primates	primate	NOUN
fnp-3025	2310	17	,	,	PUNCT
fnp-3025	2310	18	in	in	ADP
fnp-3025	2310	19	alzheimer	alzheimer	PROPN
fnp-3025	2310	20	disease	disease	PROPN
fnp-3025	2310	21	,	,	PUNCT
fnp-3025	2310	22	r.d	r.d	PROPN
fnp-3025	2310	23	.	.	PROPN
fnp-3025	2310	24	terry	terry	PROPN
fnp-3025	2310	25	,	,	PUNCT
fnp-3025	2310	26	et	et	PROPN
fnp-3025	2310	27	al	al	PROPN
fnp-3025	2310	28	.	.	PROPN
fnp-3025	2310	29	,	,	PUNCT
fnp-3025	2310	30	editors	editor	NOUN
fnp-3025	2310	31	.	.	PUNCT
fnp-3025	2311	1	1999	1999	NUM
fnp-3025	2311	2	,	,	PUNCT
fnp-3025	2311	3	lippincott	lippincott	PROPN
fnp-3025	2311	4	williams	williams	PROPN
fnp-3025	2311	5	and	and	CCONJ
fnp-3025	2311	6	wilkins	wilkins	PROPN
fnp-3025	2311	7	:	:	PUNCT
fnp-3025	2311	8	philadelphia	philadelphia	PROPN
fnp-3025	2311	9	.	.	PUNCT
fnp-3025	2312	1	p.	p.	NOUN
fnp-3025	2312	2	233	233	NUM
fnp-3025	2312	3	-	-	SYM
fnp-3025	2312	4	243	243	NUM
fnp-3025	2312	5	.	.	PUNCT
fnp-3025	2312	6	445	445	NUM
fnp-3025	2312	7	.	.	PUNCT
fnp-3025	2313	1	walker	walker	PROPN
fnp-3025	2313	2	,	,	PUNCT
fnp-3025	2313	3	l.c	l.c	PROPN
fnp-3025	2313	4	.	.	PROPN
fnp-3025	2313	5	,	,	PUNCT
fnp-3025	2313	6	animal	animal	NOUN
fnp-3025	2313	7	models	model	NOUN
fnp-3025	2313	8	of	of	ADP
fnp-3025	2313	9	cerebral	cerebral	ADJ
fnp-3025	2313	10	beta	beta	NOUN
fnp-3025	2313	11	-	-	PUNCT
fnp-3025	2313	12	amyloid	amyloid	NOUN
fnp-3025	2313	13	angiopathy	angiopathy	NOUN
fnp-3025	2313	14	.	.	PUNCT
fnp-3025	2314	1	brain	brain	NOUN
fnp-3025	2314	2	res	re	NOUN
fnp-3025	2314	3	brain	brain	NOUN
fnp-3025	2314	4	res	re	NOUN
fnp-3025	2314	5	rev	rev	PROPN
fnp-3025	2314	6	,	,	PUNCT
fnp-3025	2314	7	1997	1997	NUM
fnp-3025	2314	8	.	.	PUNCT
fnp-3025	2315	1	25(1	25(1	NUM
fnp-3025	2315	2	):	):	PUNCT
fnp-3025	2315	3	p.	p.	NOUN
fnp-3025	2315	4	70	70	NUM
fnp-3025	2315	5	-	-	SYM
fnp-3025	2315	6	84	84	NUM
fnp-3025	2315	7	.	.	PUNCT
fnp-3025	2316	1	446	446	NUM
fnp-3025	2316	2	.	.	PUNCT
fnp-3025	2317	1	jakel	jakel	PROPN
fnp-3025	2317	2	,	,	PUNCT
fnp-3025	2317	3	l.	l.	PROPN
fnp-3025	2317	4	,	,	PUNCT
fnp-3025	2317	5	et	et	PROPN
fnp-3025	2317	6	al	al	PROPN
fnp-3025	2317	7	.	.	PROPN
fnp-3025	2317	8	,	,	PUNCT
fnp-3025	2317	9	animal	animal	NOUN
fnp-3025	2317	10	models	model	NOUN
fnp-3025	2317	11	of	of	ADP
fnp-3025	2317	12	cerebral	cerebral	ADJ
fnp-3025	2317	13	amyloid	amyloid	NOUN
fnp-3025	2317	14	angiopathy	angiopathy	NOUN
fnp-3025	2317	15	.	.	PUNCT
fnp-3025	2318	1	clin	clin	PROPN
fnp-3025	2318	2	sci	sci	PROPN
fnp-3025	2318	3	(	(	PUNCT
fnp-3025	2318	4	lond	lond	PROPN
fnp-3025	2318	5	)	)	PUNCT
fnp-3025	2318	6	,	,	PUNCT
fnp-3025	2318	7	2017	2017	NUM
fnp-3025	2318	8	.	.	PUNCT
fnp-3025	2319	1	131(19	131(19	NUM
fnp-3025	2319	2	):	):	PUNCT
fnp-3025	2319	3	p.	p.	NOUN
fnp-3025	2319	4	2469	2469	NUM
fnp-3025	2319	5	-	-	SYM
fnp-3025	2319	6	2488	2488	NUM
fnp-3025	2319	7	.	.	PUNCT
fnp-3025	2320	1	447	447	NUM
fnp-3025	2320	2	.	.	PUNCT
fnp-3025	2321	1	rosen	rosen	PROPN
fnp-3025	2321	2	,	,	PUNCT
fnp-3025	2321	3	r.f	r.f	PROPN
fnp-3025	2321	4	.	.	PROPN
fnp-3025	2321	5	,	,	PUNCT
fnp-3025	2321	6	l.c	l.c	PROPN
fnp-3025	2321	7	.	.	PROPN
fnp-3025	2321	8	walker	walker	PROPN
fnp-3025	2321	9	,	,	PUNCT
fnp-3025	2321	10	and	and	CCONJ
fnp-3025	2321	11	h.	h.	PROPN
fnp-3025	2321	12	levine	levine	PROPN
fnp-3025	2321	13	,	,	PUNCT
fnp-3025	2321	14	3rd	3rd	NOUN
fnp-3025	2321	15	,	,	PUNCT
fnp-3025	2321	16	pib	pib	ADJ
fnp-3025	2321	17	binding	bind	VERB
fnp-3025	2321	18	in	in	ADP
fnp-3025	2321	19	aged	aged	ADJ
fnp-3025	2321	20	primate	primate	NOUN
fnp-3025	2321	21	brain	brain	NOUN
fnp-3025	2321	22	:	:	PUNCT
fnp-3025	2321	23	enrichment	enrichment	NOUN
fnp-3025	2321	24	of	of	ADP
fnp-3025	2321	25	high	high	ADJ
fnp-3025	2321	26	-	-	PUNCT
fnp-3025	2321	27	affinity	affinity	NOUN
fnp-3025	2321	28	sites	site	NOUN
fnp-3025	2321	29	in	in	ADP
fnp-3025	2321	30	humans	human	NOUN
fnp-3025	2321	31	with	with	ADP
fnp-3025	2321	32	alzheimer	alzheimer	PROPN
fnp-3025	2321	33	’s	’s	PART
fnp-3025	2321	34	disease	disease	NOUN
fnp-3025	2321	35	.	.	PUNCT
fnp-3025	2322	1	neurobiol	neurobiol	PROPN
fnp-3025	2322	2	aging	aging	NOUN
fnp-3025	2322	3	,	,	PUNCT
fnp-3025	2322	4	2011	2011	NUM
fnp-3025	2322	5	.	.	PUNCT
fnp-3025	2323	1	32(2	32(2	NUM
fnp-3025	2323	2	):	):	PUNCT
fnp-3025	2324	1	p.	p.	NOUN
fnp-3025	2324	2	223	223	NUM
fnp-3025	2324	3	-	-	SYM
fnp-3025	2324	4	34	34	NUM
fnp-3025	2324	5	.	.	PUNCT
fnp-3025	2324	6	448	448	NUM
fnp-3025	2324	7	.	.	PUNCT
fnp-3025	2325	1	games	games	PROPN
fnp-3025	2325	2	,	,	PUNCT
fnp-3025	2325	3	d.	d.	PROPN
fnp-3025	2325	4	,	,	PUNCT
fnp-3025	2325	5	et	et	PROPN
fnp-3025	2325	6	al	al	PROPN
fnp-3025	2325	7	.	.	PROPN
fnp-3025	2325	8	,	,	PUNCT
fnp-3025	2325	9	alzheimer	alzheimer	ADJ
fnp-3025	2325	10	-	-	PUNCT
fnp-3025	2325	11	type	type	NOUN
fnp-3025	2325	12	neuropathology	neuropathology	NOUN
fnp-3025	2325	13	in	in	ADP
fnp-3025	2325	14	transgenic	transgenic	NOUN
fnp-3025	2325	15	mice	mouse	NOUN
fnp-3025	2325	16	overexpressing	overexpresse	VERB
fnp-3025	2325	17	v717f	v717f	PROPN
fnp-3025	2325	18	beta	beta	NOUN
fnp-3025	2325	19	-	-	PUNCT
fnp-3025	2325	20	amyloid	amyloid	NOUN
fnp-3025	2325	21	precursor	precursor	NOUN
fnp-3025	2325	22	protein	protein	NOUN
fnp-3025	2325	23	.	.	PUNCT
fnp-3025	2326	1	nature	nature	NOUN
fnp-3025	2326	2	,	,	PUNCT
fnp-3025	2326	3	1995	1995	NUM
fnp-3025	2326	4	.	.	PUNCT
fnp-3025	2327	1	373(6514	373(6514	NUM
fnp-3025	2327	2	):	):	PUNCT
fnp-3025	2327	3	p.	p.	NOUN
fnp-3025	2327	4	523	523	NUM
fnp-3025	2327	5	-	-	SYM
fnp-3025	2327	6	7	7	NUM
fnp-3025	2327	7	.	.	NUM
fnp-3025	2327	8	449	449	NUM
fnp-3025	2327	9	.	.	PUNCT
fnp-3025	2328	1	hsiao	hsiao	PROPN
fnp-3025	2328	2	,	,	PUNCT
fnp-3025	2328	3	k.	k.	PROPN
fnp-3025	2328	4	,	,	PUNCT
fnp-3025	2328	5	et	et	PROPN
fnp-3025	2328	6	al	al	PROPN
fnp-3025	2328	7	.	.	PROPN
fnp-3025	2328	8	,	,	PUNCT
fnp-3025	2328	9	correlative	correlative	ADJ
fnp-3025	2328	10	memory	memory	NOUN
fnp-3025	2328	11	deficits	deficit	NOUN
fnp-3025	2328	12	,	,	PUNCT
fnp-3025	2328	13	abeta	abeta	NOUN
fnp-3025	2328	14	elevation	elevation	NOUN
fnp-3025	2328	15	,	,	PUNCT
fnp-3025	2328	16	and	and	CCONJ
fnp-3025	2328	17	amyloid	amyloid	NOUN
fnp-3025	2328	18	plaques	plaque	NOUN
fnp-3025	2328	19	in	in	ADP
fnp-3025	2328	20	transgenic	transgenic	NOUN
fnp-3025	2328	21	mice	mouse	NOUN
fnp-3025	2328	22	.	.	PUNCT
fnp-3025	2329	1	science	science	NOUN
fnp-3025	2329	2	,	,	PUNCT
fnp-3025	2329	3	1996	1996	NUM
fnp-3025	2329	4	.	.	PUNCT
fnp-3025	2330	1	274(5284	274(5284	NUM
fnp-3025	2330	2	):	):	PUNCT
fnp-3025	2331	1	p.	p.	NOUN
fnp-3025	2331	2	99	99	NUM
fnp-3025	2331	3	-	-	SYM
fnp-3025	2331	4	102	102	NUM
fnp-3025	2331	5	.	.	PUNCT
fnp-3025	2331	6	450	450	NUM
fnp-3025	2331	7	.	.	PUNCT
fnp-3025	2331	8	sturchler	sturchler	NOUN
fnp-3025	2331	9	-	-	PUNCT
fnp-3025	2331	10	pierrat	pierrat	PROPN
fnp-3025	2331	11	,	,	PUNCT
fnp-3025	2331	12	c.	c.	PROPN
fnp-3025	2331	13	,	,	PUNCT
fnp-3025	2331	14	et	et	PROPN
fnp-3025	2331	15	al	al	PROPN
fnp-3025	2331	16	.	.	PROPN
fnp-3025	2331	17	,	,	PUNCT
fnp-3025	2331	18	two	two	NUM
fnp-3025	2331	19	amyloid	amyloid	NOUN
fnp-3025	2331	20	precursor	precursor	NOUN
fnp-3025	2331	21	protein	protein	NOUN
fnp-3025	2331	22	transgenic	transgenic	NOUN
fnp-3025	2331	23	mouse	mouse	NOUN
fnp-3025	2331	24	models	model	NOUN
fnp-3025	2331	25	with	with	ADP
fnp-3025	2331	26	alzheimer	alzheimer	PROPN
fnp-3025	2331	27	disease	disease	NOUN
fnp-3025	2331	28	-	-	PUNCT
fnp-3025	2331	29	like	like	ADJ
fnp-3025	2331	30	pathology	pathology	NOUN
fnp-3025	2331	31	.	.	PUNCT
fnp-3025	2332	1	proc	proc	PROPN
fnp-3025	2332	2	natl	natl	PROPN
fnp-3025	2332	3	acad	acad	PROPN
fnp-3025	2332	4	sci	sci	PROPN
fnp-3025	2332	5	u	u	PROPN
fnp-3025	2332	6	s	s	PROPN
fnp-3025	2332	7	a	a	PRON
fnp-3025	2332	8	,	,	PUNCT
fnp-3025	2332	9	1997	1997	NUM
fnp-3025	2332	10	.	.	PUNCT
fnp-3025	2333	1	94(24	94(24	NUM
fnp-3025	2333	2	):	):	PUNCT
fnp-3025	2333	3	p.	p.	NOUN
fnp-3025	2333	4	13287	13287	NUM
fnp-3025	2333	5	-	-	SYM
fnp-3025	2333	6	92	92	NUM
fnp-3025	2333	7	.	.	PUNCT
fnp-3025	2334	1	451	451	NUM
fnp-3025	2334	2	.	.	PUNCT
fnp-3025	2335	1	duyckaerts	duyckaert	NOUN
fnp-3025	2335	2	,	,	PUNCT
fnp-3025	2335	3	c.	c.	PROPN
fnp-3025	2335	4	,	,	PUNCT
fnp-3025	2335	5	m.c	m.c	PROPN
fnp-3025	2335	6	.	.	PROPN
fnp-3025	2335	7	potier	potier	NOUN
fnp-3025	2335	8	,	,	PUNCT
fnp-3025	2335	9	and	and	CCONJ
fnp-3025	2335	10	b.	b.	PROPN
fnp-3025	2335	11	delatour	delatour	PROPN
fnp-3025	2335	12	,	,	PUNCT
fnp-3025	2335	13	alzheimer	alzheimer	NOUN
fnp-3025	2335	14	disease	disease	NOUN
fnp-3025	2335	15	models	model	NOUN
fnp-3025	2335	16	and	and	CCONJ
fnp-3025	2335	17	human	human	ADJ
fnp-3025	2335	18	neuropathology	neuropathology	NOUN
fnp-3025	2335	19	:	:	PUNCT
fnp-3025	2335	20	similarities	similarity	NOUN
fnp-3025	2335	21	and	and	CCONJ
fnp-3025	2335	22	differences	difference	NOUN
fnp-3025	2335	23	.	.	PUNCT
fnp-3025	2336	1	acta	acta	PROPN
fnp-3025	2336	2	neuropathol	neuropathol	PROPN
fnp-3025	2336	3	,	,	PUNCT
fnp-3025	2336	4	2008	2008	NUM
fnp-3025	2336	5	.	.	PUNCT
fnp-3025	2337	1	115(1	115(1	NUM
fnp-3025	2337	2	):	):	PUNCT
fnp-3025	2337	3	p.	p.	NOUN
fnp-3025	2337	4	5	5	NUM
fnp-3025	2337	5	-	-	SYM
fnp-3025	2337	6	38	38	NUM
fnp-3025	2337	7	.	.	PUNCT
fnp-3025	2338	1	452	452	NUM
fnp-3025	2338	2	.	.	PUNCT
fnp-3025	2338	3	jucker	jucker	PROPN
fnp-3025	2338	4	,	,	PUNCT
fnp-3025	2338	5	m.	m.	NOUN
fnp-3025	2338	6	,	,	PUNCT
fnp-3025	2338	7	the	the	DET
fnp-3025	2338	8	benefits	benefit	NOUN
fnp-3025	2338	9	and	and	CCONJ
fnp-3025	2338	10	limitations	limitation	NOUN
fnp-3025	2338	11	of	of	ADP
fnp-3025	2338	12	animal	animal	NOUN
fnp-3025	2338	13	models	model	NOUN
fnp-3025	2338	14	for	for	ADP
fnp-3025	2338	15	translational	translational	ADJ
fnp-3025	2338	16	research	research	NOUN
fnp-3025	2338	17	in	in	ADP
fnp-3025	2338	18	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2338	19	diseases	disease	NOUN
fnp-3025	2338	20	.	.	PUNCT
fnp-3025	2339	1	nat	nat	PROPN
fnp-3025	2339	2	med	med	PROPN
fnp-3025	2339	3	,	,	PUNCT
fnp-3025	2339	4	2010	2010	NUM
fnp-3025	2339	5	.	.	PUNCT
fnp-3025	2340	1	16(11	16(11	NUM
fnp-3025	2340	2	):	):	PUNCT
fnp-3025	2340	3	p.	p.	NOUN
fnp-3025	2340	4	1210	1210	NUM
fnp-3025	2340	5	-	-	SYM
fnp-3025	2340	6	4	4	NUM
fnp-3025	2340	7	.	.	NUM
fnp-3025	2340	8	453	453	NUM
fnp-3025	2340	9	.	.	PUNCT
fnp-3025	2341	1	myers	myer	NOUN
fnp-3025	2341	2	,	,	PUNCT
fnp-3025	2341	3	a.	a.	NOUN
fnp-3025	2341	4	and	and	CCONJ
fnp-3025	2341	5	p.	p.	PROPN
fnp-3025	2341	6	mcgonigle	mcgonigle	PROPN
fnp-3025	2341	7	,	,	PUNCT
fnp-3025	2341	8	overview	overview	NOUN
fnp-3025	2341	9	of	of	ADP
fnp-3025	2341	10	transgenic	transgenic	NOUN
fnp-3025	2341	11	mouse	mouse	NOUN
fnp-3025	2341	12	models	model	NOUN
fnp-3025	2341	13	for	for	ADP
fnp-3025	2341	14	alzheimer	alzheimer	PROPN
fnp-3025	2341	15	’s	’s	PART
fnp-3025	2341	16	disease	disease	NOUN
fnp-3025	2341	17	.	.	PUNCT
fnp-3025	2342	1	curr	curr	PROPN
fnp-3025	2342	2	protoc	protoc	PROPN
fnp-3025	2342	3	neurosci	neurosci	PROPN
fnp-3025	2342	4	,	,	PUNCT
fnp-3025	2342	5	2019	2019	NUM
fnp-3025	2342	6	.	.	PUNCT
fnp-3025	2343	1	89(1	89(1	NUM
fnp-3025	2343	2	):	):	PUNCT
fnp-3025	2343	3	p.	p.	NOUN
fnp-3025	2343	4	e81	e81	NOUN
fnp-3025	2343	5	.	.	PUNCT
fnp-3025	2344	1	454	454	NUM
fnp-3025	2344	2	.	.	PUNCT
fnp-3025	2345	1	greeve	greeve	PROPN
fnp-3025	2345	2	,	,	PUNCT
fnp-3025	2345	3	i.	i.	PROPN
fnp-3025	2345	4	,	,	PUNCT
fnp-3025	2345	5	et	et	PROPN
fnp-3025	2345	6	al	al	PROPN
fnp-3025	2345	7	.	.	PROPN
fnp-3025	2345	8	,	,	PUNCT
fnp-3025	2345	9	age	age	NOUN
fnp-3025	2345	10	-	-	PUNCT
fnp-3025	2345	11	dependent	dependent	ADJ
fnp-3025	2345	12	neurodegeneration	neurodegeneration	NOUN
fnp-3025	2345	13	and	and	CCONJ
fnp-3025	2345	14	alzheimer	alzheimer	NOUN
fnp-3025	2345	15	-	-	PUNCT
fnp-3025	2345	16	amyloid	amyloid	NOUN
fnp-3025	2345	17	plaque	plaque	NOUN
fnp-3025	2345	18	formation	formation	NOUN
fnp-3025	2345	19	in	in	ADP
fnp-3025	2345	20	transgenic	transgenic	NOUN
fnp-3025	2345	21	drosophila	drosophila	NOUN
fnp-3025	2345	22	.	.	PUNCT
fnp-3025	2346	1	j	j	PROPN
fnp-3025	2346	2	neurosci	neurosci	PROPN
fnp-3025	2346	3	,	,	PUNCT
fnp-3025	2346	4	2004	2004	NUM
fnp-3025	2346	5	.	.	PUNCT
fnp-3025	2347	1	24(16	24(16	NUM
fnp-3025	2347	2	):	):	PUNCT
fnp-3025	2347	3	p.	p.	NOUN
fnp-3025	2347	4	3899	3899	NUM
fnp-3025	2347	5	-	-	SYM
fnp-3025	2347	6	906	906	NUM
fnp-3025	2347	7	.	.	PUNCT
fnp-3025	2348	1	455	455	NUM
fnp-3025	2348	2	.	.	PUNCT
fnp-3025	2349	1	iijima	iijima	PROPN
fnp-3025	2349	2	-	-	PUNCT
fnp-3025	2349	3	ando	ando	PROPN
fnp-3025	2349	4	,	,	PUNCT
fnp-3025	2349	5	k.	k.	PROPN
fnp-3025	2349	6	and	and	CCONJ
fnp-3025	2349	7	k.	k.	PROPN
fnp-3025	2349	8	iijima	iijima	PROPN
fnp-3025	2349	9	,	,	PUNCT
fnp-3025	2349	10	transgenic	transgenic	NOUN
fnp-3025	2349	11	drosophila	drosophila	NOUN
fnp-3025	2349	12	models	model	NOUN
fnp-3025	2349	13	of	of	ADP
fnp-3025	2349	14	alzheimer	alzheimer	PROPN
fnp-3025	2349	15	’s	’s	PART
fnp-3025	2349	16	disease	disease	NOUN
fnp-3025	2349	17	and	and	CCONJ
fnp-3025	2349	18	tauopathies	tauopathie	NOUN
fnp-3025	2349	19	.	.	PUNCT
fnp-3025	2350	1	brain	brain	NOUN
fnp-3025	2350	2	struct	struct	NOUN
fnp-3025	2350	3	funct	funct	NOUN
fnp-3025	2350	4	,	,	PUNCT
fnp-3025	2350	5	2010	2010	NUM
fnp-3025	2350	6	.	.	PUNCT
fnp-3025	2351	1	214(2	214(2	NUM
fnp-3025	2351	2	-	-	SYM
fnp-3025	2351	3	3	3	NUM
fnp-3025	2351	4	):	):	PUNCT
fnp-3025	2351	5	p.	p.	NOUN
fnp-3025	2351	6	245	245	NUM
fnp-3025	2351	7	-	-	SYM
fnp-3025	2351	8	62	62	NUM
fnp-3025	2351	9	.	.	PUNCT
fnp-3025	2352	1	456	456	NUM
fnp-3025	2352	2	.	.	PUNCT
fnp-3025	2353	1	jeon	jeon	PROPN
fnp-3025	2353	2	,	,	PUNCT
fnp-3025	2353	3	y.	y.	PROPN
fnp-3025	2353	4	,	,	PUNCT
fnp-3025	2353	5	et	et	PROPN
fnp-3025	2353	6	al	al	PROPN
fnp-3025	2353	7	.	.	PROPN
fnp-3025	2353	8	,	,	PUNCT
fnp-3025	2353	9	genetic	genetic	ADJ
fnp-3025	2353	10	dissection	dissection	NOUN
fnp-3025	2353	11	of	of	ADP
fnp-3025	2353	12	alzheimer	alzheimer	PROPN
fnp-3025	2353	13	’s	’s	PART
fnp-3025	2353	14	disease	disease	NOUN
fnp-3025	2353	15	using	use	VERB
fnp-3025	2353	16	drosophila	drosophila	NOUN
fnp-3025	2353	17	models	model	NOUN
fnp-3025	2353	18	.	.	PUNCT
fnp-3025	2354	1	int	int	PROPN
fnp-3025	2354	2	j	j	PROPN
fnp-3025	2354	3	mol	mol	ADP
fnp-3025	2354	4	sci	sci	PROPN
fnp-3025	2354	5	,	,	PUNCT
fnp-3025	2354	6	2020	2020	NUM
fnp-3025	2354	7	.	.	PUNCT
fnp-3025	2355	1	21(3	21(3	NUM
fnp-3025	2355	2	):	):	PUNCT
fnp-3025	2355	3	p.	p.	NOUN
fnp-3025	2355	4	884	884	NUM
fnp-3025	2355	5	.	.	PUNCT
fnp-3025	2355	6	457	457	NUM
fnp-3025	2355	7	.	.	PUNCT
fnp-3025	2356	1	link	link	PROPN
fnp-3025	2356	2	,	,	PUNCT
fnp-3025	2356	3	c.d	c.d	PROPN
fnp-3025	2356	4	.	.	PROPN
fnp-3025	2356	5	,	,	PUNCT
fnp-3025	2356	6	c.	c.	PROPN
fnp-3025	2356	7	elegans	elegans	PROPN
fnp-3025	2356	8	models	model	NOUN
fnp-3025	2356	9	of	of	ADP
fnp-3025	2356	10	age	age	NOUN
fnp-3025	2356	11	-	-	PUNCT
fnp-3025	2356	12	associated	associate	VERB
fnp-3025	2356	13	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2356	14	diseases	disease	NOUN
fnp-3025	2356	15	:	:	PUNCT
fnp-3025	2356	16	lessons	lesson	NOUN
fnp-3025	2356	17	from	from	ADP
fnp-3025	2356	18	transgenic	transgenic	NOUN
fnp-3025	2356	19	worm	worm	NOUN
fnp-3025	2356	20	models	model	NOUN
fnp-3025	2356	21	of	of	ADP
fnp-3025	2356	22	alzheimer	alzheimer	PROPN
fnp-3025	2356	23	’s	’s	PART
fnp-3025	2356	24	disease	disease	NOUN
fnp-3025	2356	25	.	.	PUNCT
fnp-3025	2357	1	exp	exp	NOUN
fnp-3025	2357	2	gerontol	gerontol	NOUN
fnp-3025	2357	3	,	,	PUNCT
fnp-3025	2357	4	2006	2006	NUM
fnp-3025	2357	5	.	.	PUNCT
fnp-3025	2358	1	41(10	41(10	NUM
fnp-3025	2358	2	):	):	PUNCT
fnp-3025	2358	3	p.	p.	NOUN
fnp-3025	2358	4	1007	1007	NUM
fnp-3025	2358	5	-	-	SYM
fnp-3025	2358	6	13	13	NUM
fnp-3025	2358	7	.	.	PUNCT
fnp-3025	2359	1	458	458	NUM
fnp-3025	2359	2	.	.	PUNCT
fnp-3025	2360	1	link	link	PROPN
fnp-3025	2360	2	,	,	PUNCT
fnp-3025	2360	3	c.d	c.d	PROPN
fnp-3025	2360	4	.	.	PROPN
fnp-3025	2360	5	,	,	PUNCT
fnp-3025	2360	6	et	et	PROPN
fnp-3025	2360	7	al	al	PROPN
fnp-3025	2360	8	.	.	PROPN
fnp-3025	2360	9	,	,	PUNCT
fnp-3025	2360	10	visualization	visualization	NOUN
fnp-3025	2360	11	of	of	ADP
fnp-3025	2360	12	fibrillar	fibrillar	ADJ
fnp-3025	2360	13	amyloid	amyloid	NOUN
fnp-3025	2360	14	deposits	deposit	NOUN
fnp-3025	2360	15	in	in	ADP
fnp-3025	2360	16	living	living	NOUN
fnp-3025	2360	17	,	,	PUNCT
fnp-3025	2360	18	transgenic	transgenic	NOUN
fnp-3025	2360	19	caenorhabditis	caenorhabditis	ADJ
fnp-3025	2360	20	elegans	elegan	NOUN
fnp-3025	2360	21	animals	animal	NOUN
fnp-3025	2360	22	using	use	VERB
fnp-3025	2360	23	the	the	DET
fnp-3025	2360	24	sensitive	sensitive	ADJ
fnp-3025	2360	25	amyloid	amyloid	NOUN
fnp-3025	2360	26	dye	dye	NOUN
fnp-3025	2360	27	,	,	PUNCT
fnp-3025	2360	28	x-34	x-34	PROPN
fnp-3025	2360	29	.	.	PUNCT
fnp-3025	2361	1	neurobiol	neurobiol	PROPN
fnp-3025	2361	2	aging	aging	NOUN
fnp-3025	2361	3	,	,	PUNCT
fnp-3025	2361	4	2001	2001	NUM
fnp-3025	2361	5	.	.	PUNCT
fnp-3025	2362	1	22(2	22(2	NUM
fnp-3025	2362	2	):	):	PUNCT
fnp-3025	2362	3	p.	p.	NOUN
fnp-3025	2362	4	217	217	NUM
fnp-3025	2362	5	-	-	SYM
fnp-3025	2362	6	26	26	NUM
fnp-3025	2362	7	.	.	PUNCT
fnp-3025	2363	1	459	459	NUM
fnp-3025	2363	2	.	.	PUNCT
fnp-3025	2364	1	dawson	dawson	PROPN
fnp-3025	2364	2	,	,	PUNCT
fnp-3025	2364	3	t.m	t.m	PROPN
fnp-3025	2364	4	.	.	PROPN
fnp-3025	2364	5	,	,	PUNCT
fnp-3025	2364	6	t.e	t.e	PROPN
fnp-3025	2364	7	.	.	PUNCT
fnp-3025	2364	8	golde	golde	PROPN
fnp-3025	2364	9	,	,	PUNCT
fnp-3025	2364	10	and	and	CCONJ
fnp-3025	2364	11	c.	c.	PROPN
fnp-3025	2364	12	lagier	lagier	PROPN
fnp-3025	2364	13	-	-	PUNCT
fnp-3025	2364	14	tourenne	tourenne	NOUN
fnp-3025	2364	15	,	,	PUNCT
fnp-3025	2364	16	animal	animal	NOUN
fnp-3025	2364	17	models	model	NOUN
fnp-3025	2364	18	of	of	ADP
fnp-3025	2364	19	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2364	20	diseases	disease	NOUN
fnp-3025	2364	21	.	.	PUNCT
fnp-3025	2365	1	nat	nat	PROPN
fnp-3025	2365	2	neurosci	neurosci	PROPN
fnp-3025	2365	3	,	,	PUNCT
fnp-3025	2365	4	2018	2018	NUM
fnp-3025	2365	5	.	.	PUNCT
fnp-3025	2366	1	21(10	21(10	NUM
fnp-3025	2366	2	):	):	PUNCT
fnp-3025	2366	3	p.	p.	NOUN
fnp-3025	2366	4	1370	1370	NUM
fnp-3025	2366	5	-	-	SYM
fnp-3025	2366	6	1379	1379	NUM
fnp-3025	2366	7	.	.	PUNCT
fnp-3025	2367	1	460	460	NUM
fnp-3025	2367	2	.	.	PUNCT
fnp-3025	2367	3	gotz	gotz	PROPN
fnp-3025	2367	4	,	,	PUNCT
fnp-3025	2367	5	j.	j.	PROPN
fnp-3025	2367	6	and	and	CCONJ
fnp-3025	2367	7	l.m	l.m	PROPN
fnp-3025	2367	8	.	.	PROPN
fnp-3025	2367	9	ittner	ittner	PROPN
fnp-3025	2367	10	,	,	PUNCT
fnp-3025	2367	11	animal	animal	NOUN
fnp-3025	2367	12	models	model	NOUN
fnp-3025	2367	13	of	of	ADP
fnp-3025	2367	14	alzheimer	alzheimer	PROPN
fnp-3025	2367	15	’s	’s	PART
fnp-3025	2367	16	disease	disease	NOUN
fnp-3025	2367	17	and	and	CCONJ
fnp-3025	2367	18	frontotemporal	frontotemporal	ADJ
fnp-3025	2367	19	dementia	dementia	NOUN
fnp-3025	2367	20	.	.	PUNCT
fnp-3025	2368	1	nat	nat	PROPN
fnp-3025	2368	2	rev	rev	PROPN
fnp-3025	2368	3	neurosci	neurosci	PROPN
fnp-3025	2368	4	,	,	PUNCT
fnp-3025	2368	5	2008	2008	NUM
fnp-3025	2368	6	.	.	PUNCT
fnp-3025	2369	1	9(7	9(7	NUM
fnp-3025	2369	2	):	):	PUNCT
fnp-3025	2369	3	p.	p.	NOUN
fnp-3025	2369	4	532	532	NUM
fnp-3025	2369	5	-	-	SYM
fnp-3025	2369	6	44	44	NUM
fnp-3025	2369	7	.	.	PUNCT
fnp-3025	2370	1	461	461	NUM
fnp-3025	2370	2	.	.	PUNCT
fnp-3025	2371	1	rockenstein	rockenstein	PROPN
fnp-3025	2371	2	,	,	PUNCT
fnp-3025	2371	3	e.	e.	PROPN
fnp-3025	2371	4	,	,	PUNCT
fnp-3025	2371	5	l.	l.	PROPN
fnp-3025	2371	6	crews	crews	PROPN
fnp-3025	2371	7	,	,	PUNCT
fnp-3025	2371	8	and	and	CCONJ
fnp-3025	2371	9	e.	e.	PROPN
fnp-3025	2371	10	masliah	masliah	PROPN
fnp-3025	2371	11	,	,	PUNCT
fnp-3025	2371	12	transgenic	transgenic	NOUN
fnp-3025	2371	13	animal	animal	NOUN
fnp-3025	2371	14	models	model	NOUN
fnp-3025	2371	15	of	of	ADP
fnp-3025	2371	16	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2371	17	diseases	disease	NOUN
fnp-3025	2371	18	and	and	CCONJ
fnp-3025	2371	19	their	their	PRON
fnp-3025	2371	20	application	application	NOUN
fnp-3025	2371	21	to	to	ADP
fnp-3025	2371	22	treatment	treatment	NOUN
fnp-3025	2371	23	development	development	NOUN
fnp-3025	2371	24	.	.	PUNCT
fnp-3025	2372	1	adv	adv	PROPN
fnp-3025	2372	2	drug	drug	PROPN
fnp-3025	2372	3	deliv	deliv	PROPN
fnp-3025	2372	4	rev	rev	PROPN
fnp-3025	2372	5	,	,	PUNCT
fnp-3025	2372	6	2007	2007	NUM
fnp-3025	2372	7	.	.	PUNCT
fnp-3025	2373	1	59(11	59(11	NUM
fnp-3025	2373	2	):	):	PUNCT
fnp-3025	2373	3	p.	p.	NOUN
fnp-3025	2373	4	1093	1093	NUM
fnp-3025	2373	5	-	-	SYM
fnp-3025	2373	6	102	102	NUM
fnp-3025	2373	7	.	.	PUNCT
fnp-3025	2374	1	462	462	NUM
fnp-3025	2374	2	.	.	PUNCT
fnp-3025	2374	3	gotz	gotz	PROPN
fnp-3025	2374	4	,	,	PUNCT
fnp-3025	2374	5	j.	j.	PROPN
fnp-3025	2374	6	,	,	PUNCT
fnp-3025	2374	7	l.g	l.g	PROPN
fnp-3025	2374	8	.	.	PROPN
fnp-3025	2374	9	bodea	bodea	PROPN
fnp-3025	2374	10	,	,	PUNCT
fnp-3025	2374	11	and	and	CCONJ
fnp-3025	2374	12	m.	m.	NOUN
fnp-3025	2374	13	goedert	goedert	PROPN
fnp-3025	2374	14	,	,	PUNCT
fnp-3025	2374	15	rodent	rodent	NOUN
fnp-3025	2374	16	models	model	NOUN
fnp-3025	2374	17	for	for	ADP
fnp-3025	2374	18	alzheimer	alzheimer	PROPN
fnp-3025	2374	19	disease	disease	NOUN
fnp-3025	2374	20	.	.	PUNCT
fnp-3025	2375	1	nat	nat	PROPN
fnp-3025	2375	2	rev	rev	PROPN
fnp-3025	2375	3	neurosci	neurosci	PROPN
fnp-3025	2375	4	,	,	PUNCT
fnp-3025	2375	5	2018	2018	NUM
fnp-3025	2375	6	.	.	PUNCT
fnp-3025	2376	1	19(10	19(10	NUM
fnp-3025	2376	2	):	):	PUNCT
fnp-3025	2376	3	p.	p.	NOUN
fnp-3025	2376	4	583	583	NUM
fnp-3025	2376	5	-	-	SYM
fnp-3025	2376	6	598	598	NUM
fnp-3025	2376	7	.	.	PUNCT
fnp-3025	2376	8	463	463	NUM
fnp-3025	2376	9	.	.	PUNCT
fnp-3025	2377	1	kitazawa	kitazawa	PROPN
fnp-3025	2377	2	,	,	PUNCT
fnp-3025	2377	3	m.	m.	NOUN
fnp-3025	2377	4	,	,	PUNCT
fnp-3025	2377	5	r.	r.	PROPN
fnp-3025	2377	6	medeiros	medeiros	PROPN
fnp-3025	2377	7	,	,	PUNCT
fnp-3025	2377	8	and	and	CCONJ
fnp-3025	2377	9	f.m	f.m	PROPN
fnp-3025	2377	10	.	.	PROPN
fnp-3025	2377	11	laferla	laferla	NOUN
fnp-3025	2377	12	,	,	PUNCT
fnp-3025	2377	13	transgenic	transgenic	NOUN
fnp-3025	2377	14	mouse	mouse	NOUN
fnp-3025	2377	15	models	model	NOUN
fnp-3025	2377	16	of	of	ADP
fnp-3025	2377	17	alzheimer	alzheimer	PROPN
fnp-3025	2377	18	disease	disease	PROPN
fnp-3025	2377	19	:	:	PUNCT
fnp-3025	2377	20	developing	develop	VERB
fnp-3025	2377	21	a	a	DET
fnp-3025	2377	22	better	well	ADJ
fnp-3025	2377	23	model	model	NOUN
fnp-3025	2377	24	as	as	ADP
fnp-3025	2377	25	a	a	DET
fnp-3025	2377	26	tool	tool	NOUN
fnp-3025	2377	27	for	for	ADP
fnp-3025	2377	28	therapeutic	therapeutic	ADJ
fnp-3025	2377	29	interventions	intervention	NOUN
fnp-3025	2377	30	.	.	PUNCT
fnp-3025	2378	1	curr	curr	PROPN
fnp-3025	2378	2	pharm	pharm	PROPN
fnp-3025	2378	3	des	des	PROPN
fnp-3025	2378	4	,	,	PUNCT
fnp-3025	2378	5	2012	2012	NUM
fnp-3025	2378	6	.	.	PUNCT
fnp-3025	2379	1	18(8	18(8	NUM
fnp-3025	2379	2	):	):	PUNCT
fnp-3025	2380	1	p.	p.	NOUN
fnp-3025	2380	2	1131	1131	NUM
fnp-3025	2380	3	-	-	SYM
fnp-3025	2380	4	47	47	NUM
fnp-3025	2380	5	.	.	PUNCT
fnp-3025	2381	1	464	464	NUM
fnp-3025	2381	2	.	.	PUNCT
fnp-3025	2382	1	walker	walker	PROPN
fnp-3025	2382	2	,	,	PUNCT
fnp-3025	2382	3	l.c	l.c	PROPN
fnp-3025	2382	4	.	.	PROPN
fnp-3025	2382	5	,	,	PUNCT
fnp-3025	2382	6	et	et	PROPN
fnp-3025	2382	7	al	al	PROPN
fnp-3025	2382	8	.	.	PROPN
fnp-3025	2382	9	,	,	PUNCT
fnp-3025	2382	10	labeling	labeling	NOUN
fnp-3025	2382	11	of	of	ADP
fnp-3025	2382	12	cerebral	cerebral	ADJ
fnp-3025	2382	13	amyloid	amyloid	NOUN
fnp-3025	2382	14	in	in	ADP
fnp-3025	2382	15	vivo	vivo	NOUN
fnp-3025	2382	16	with	with	ADP
fnp-3025	2382	17	a	a	DET
fnp-3025	2382	18	monoclonal	monoclonal	NOUN
fnp-3025	2382	19	antibody	antibody	NOUN
fnp-3025	2382	20	.	.	PUNCT
fnp-3025	2383	1	j	j	PROPN
fnp-3025	2383	2	neuropathol	neuropathol	PROPN
fnp-3025	2383	3	exp	exp	PROPN
fnp-3025	2383	4	neurol	neurol	PROPN
fnp-3025	2383	5	,	,	PUNCT
fnp-3025	2383	6	1994	1994	NUM
fnp-3025	2383	7	.	.	PUNCT
fnp-3025	2384	1	53(4	53(4	NUM
fnp-3025	2384	2	):	):	PUNCT
fnp-3025	2384	3	p.	p.	NOUN
fnp-3025	2384	4	377	377	NUM
fnp-3025	2384	5	-	-	SYM
fnp-3025	2384	6	83	83	NUM
fnp-3025	2384	7	.	.	PUNCT
fnp-3025	2385	1	465	465	NUM
fnp-3025	2385	2	.	.	PUNCT
fnp-3025	2386	1	schenk	schenk	PROPN
fnp-3025	2386	2	,	,	PUNCT
fnp-3025	2386	3	d.	d.	PROPN
fnp-3025	2386	4	,	,	PUNCT
fnp-3025	2386	5	et	et	PROPN
fnp-3025	2386	6	al	al	PROPN
fnp-3025	2386	7	.	.	PROPN
fnp-3025	2386	8	,	,	PUNCT
fnp-3025	2386	9	immunization	immunization	NOUN
fnp-3025	2386	10	with	with	ADP
fnp-3025	2386	11	amyloid	amyloid	NOUN
fnp-3025	2386	12	-	-	PUNCT
fnp-3025	2386	13	beta	beta	NOUN
fnp-3025	2386	14	attenuates	attenuate	NOUN
fnp-3025	2386	15	alzheimer	alzheimer	NOUN
fnp-3025	2386	16	-	-	PUNCT
fnp-3025	2386	17	disease	disease	NOUN
fnp-3025	2386	18	-	-	PUNCT
fnp-3025	2386	19	like	like	ADJ
fnp-3025	2386	20	pathology	pathology	NOUN
fnp-3025	2386	21	in	in	ADP
fnp-3025	2386	22	the	the	DET
fnp-3025	2386	23	pdapp	pdapp	NOUN
fnp-3025	2386	24	mouse	mouse	NOUN
fnp-3025	2386	25	.	.	PUNCT
fnp-3025	2387	1	nature	nature	PROPN
fnp-3025	2387	2	,	,	PUNCT
fnp-3025	2387	3	1999	1999	NUM
fnp-3025	2387	4	.	.	PUNCT
fnp-3025	2388	1	400(6740	400(6740	NUM
fnp-3025	2388	2	):	):	PUNCT
fnp-3025	2389	1	p.	p.	NOUN
fnp-3025	2389	2	173	173	NUM
fnp-3025	2389	3	-	-	SYM
fnp-3025	2389	4	7	7	NUM
fnp-3025	2389	5	.	.	NOUN
fnp-3025	2389	6	466	466	NUM
fnp-3025	2389	7	.	.	PUNCT
fnp-3025	2390	1	braakman	braakman	NOUN
fnp-3025	2390	2	,	,	PUNCT
fnp-3025	2390	3	n.	n.	PROPN
fnp-3025	2390	4	,	,	PUNCT
fnp-3025	2390	5	et	et	PROPN
fnp-3025	2390	6	al	al	PROPN
fnp-3025	2390	7	.	.	PROPN
fnp-3025	2390	8	,	,	PUNCT
fnp-3025	2390	9	longitudinal	longitudinal	ADJ
fnp-3025	2390	10	assessment	assessment	NOUN
fnp-3025	2390	11	of	of	ADP
fnp-3025	2390	12	alzheimer	alzheimer	PROPN
fnp-3025	2390	13	’s	’s	PART
fnp-3025	2390	14	beta	beta	NOUN
fnp-3025	2390	15	-	-	PUNCT
fnp-3025	2390	16	amyloid	amyloid	NOUN
fnp-3025	2390	17	plaque	plaque	NOUN
fnp-3025	2390	18	development	development	NOUN
fnp-3025	2390	19	in	in	ADP
fnp-3025	2390	20	transgenic	transgenic	NOUN
fnp-3025	2390	21	mice	mouse	NOUN
fnp-3025	2390	22	monitored	monitor	VERB
fnp-3025	2390	23	by	by	ADP
fnp-3025	2390	24	in	in	ADP
fnp-3025	2390	25	vivo	vivo	ADJ
fnp-3025	2390	26	magnetic	magnetic	ADJ
fnp-3025	2390	27	resonance	resonance	NOUN
fnp-3025	2390	28	microimaging	microimaging	NOUN
fnp-3025	2390	29	.	.	PUNCT
fnp-3025	2391	1	j	j	PROPN
fnp-3025	2391	2	magn	magn	PROPN
fnp-3025	2391	3	reson	reson	PROPN
fnp-3025	2391	4	imaging	imaging	PROPN
fnp-3025	2391	5	,	,	PUNCT
fnp-3025	2391	6	2006	2006	NUM
fnp-3025	2391	7	.	.	PUNCT
fnp-3025	2392	1	24(3	24(3	NUM
fnp-3025	2392	2	):	):	PUNCT
fnp-3025	2392	3	p.	p.	NOUN
fnp-3025	2392	4	530	530	NUM
fnp-3025	2392	5	-	-	SYM
fnp-3025	2392	6	6	6	NUM
fnp-3025	2392	7	.	.	NOUN
fnp-3025	2392	8	467	467	NUM
fnp-3025	2392	9	.	.	PUNCT
fnp-3025	2392	10	christie	christie	PROPN
fnp-3025	2392	11	,	,	PUNCT
fnp-3025	2392	12	r.h	r.h	PROPN
fnp-3025	2392	13	.	.	PROPN
fnp-3025	2392	14	,	,	PUNCT
fnp-3025	2392	15	et	et	PROPN
fnp-3025	2392	16	al	al	PROPN
fnp-3025	2392	17	.	.	PROPN
fnp-3025	2392	18	,	,	PUNCT
fnp-3025	2392	19	growth	growth	NOUN
fnp-3025	2392	20	arrest	arrest	NOUN
fnp-3025	2392	21	of	of	ADP
fnp-3025	2392	22	individual	individual	ADJ
fnp-3025	2392	23	senile	senile	ADJ
fnp-3025	2392	24	plaques	plaque	NOUN
fnp-3025	2392	25	in	in	ADP
fnp-3025	2392	26	a	a	DET
fnp-3025	2392	27	model	model	NOUN
fnp-3025	2392	28	of	of	ADP
fnp-3025	2392	29	alzheimer	alzheimer	PROPN
fnp-3025	2392	30	’s	’s	PART
fnp-3025	2392	31	disease	disease	NOUN
fnp-3025	2392	32	observed	observe	VERB
fnp-3025	2392	33	by	by	ADP
fnp-3025	2392	34	in	in	ADP
fnp-3025	2392	35	vivo	vivo	ADJ
fnp-3025	2392	36	multiphoton	multiphoton	NOUN
fnp-3025	2392	37	microscopy	microscopy	NOUN
fnp-3025	2392	38	.	.	PUNCT
fnp-3025	2393	1	j	j	PROPN
fnp-3025	2393	2	neurosci	neurosci	PROPN
fnp-3025	2393	3	,	,	PUNCT
fnp-3025	2393	4	2001	2001	NUM
fnp-3025	2393	5	.	.	PUNCT
fnp-3025	2394	1	21(3	21(3	NUM
fnp-3025	2394	2	):	):	PUNCT
fnp-3025	2394	3	p.	p.	NOUN
fnp-3025	2394	4	858	858	NUM
fnp-3025	2394	5	-	-	SYM
fnp-3025	2394	6	64	64	NUM
fnp-3025	2394	7	.	.	PUNCT
fnp-3025	2395	1	468	468	NUM
fnp-3025	2395	2	.	.	PUNCT
fnp-3025	2395	3	dong	dong	PROPN
fnp-3025	2395	4	,	,	PUNCT
fnp-3025	2395	5	j.	j.	PROPN
fnp-3025	2395	6	,	,	PUNCT
fnp-3025	2395	7	et	et	PROPN
fnp-3025	2395	8	al	al	PROPN
fnp-3025	2395	9	.	.	PROPN
fnp-3025	2395	10	,	,	PUNCT
fnp-3025	2395	11	multiphoton	multiphoton	NOUN
fnp-3025	2395	12	in	in	ADP
fnp-3025	2395	13	vivo	vivo	ADJ
fnp-3025	2395	14	imaging	imaging	NOUN
fnp-3025	2395	15	of	of	ADP
fnp-3025	2395	16	amyloid	amyloid	NOUN
fnp-3025	2395	17	in	in	ADP
fnp-3025	2395	18	animal	animal	NOUN
fnp-3025	2395	19	models	model	NOUN
fnp-3025	2395	20	of	of	ADP
fnp-3025	2395	21	alzheimer	alzheimer	PROPN
fnp-3025	2395	22	’s	’s	PART
fnp-3025	2395	23	disease	disease	NOUN
fnp-3025	2395	24	.	.	PUNCT
fnp-3025	2396	1	neuropharmacology	neuropharmacology	NOUN
fnp-3025	2396	2	,	,	PUNCT
fnp-3025	2396	3	2010	2010	NUM
fnp-3025	2396	4	.	.	PUNCT
fnp-3025	2397	1	59(4	59(4	NUM
fnp-3025	2397	2	-	-	SYM
fnp-3025	2397	3	5	5	NUM
fnp-3025	2397	4	):	):	PUNCT
fnp-3025	2397	5	p.	p.	NOUN
fnp-3025	2397	6	268	268	NUM
fnp-3025	2397	7	-	-	SYM
fnp-3025	2397	8	75	75	NUM
fnp-3025	2397	9	.	.	PUNCT
fnp-3025	2398	1	469	469	X
fnp-3025	2398	2	.	.	PUNCT
fnp-3025	2399	1	rominger	rominger	PROPN
fnp-3025	2399	2	,	,	PUNCT
fnp-3025	2399	3	a.	a.	PROPN
fnp-3025	2399	4	,	,	PUNCT
fnp-3025	2399	5	et	et	PROPN
fnp-3025	2399	6	al	al	PROPN
fnp-3025	2399	7	.	.	PROPN
fnp-3025	2399	8	,	,	PUNCT
fnp-3025	2399	9	longitudinal	longitudinal	ADJ
fnp-3025	2399	10	assessment	assessment	NOUN
fnp-3025	2399	11	of	of	ADP
fnp-3025	2399	12	cerebral	cerebral	ADJ
fnp-3025	2399	13	beta	beta	NOUN
fnp-3025	2399	14	-	-	PUNCT
fnp-3025	2399	15	amyloid	amyloid	NOUN
fnp-3025	2399	16	deposition	deposition	NOUN
fnp-3025	2399	17	in	in	ADP
fnp-3025	2399	18	mice	mice	NOUN
fnp-3025	2399	19	overexpressing	overexpresse	VERB
fnp-3025	2399	20	swedish	swedish	ADJ
fnp-3025	2399	21	mutant	mutant	ADJ
fnp-3025	2399	22	beta	beta	NOUN
fnp-3025	2399	23	-	-	PUNCT
fnp-3025	2399	24	amyloid	amyloid	NOUN
fnp-3025	2399	25	precursor	precursor	NOUN
fnp-3025	2399	26	protein	protein	NOUN
fnp-3025	2399	27	using	use	VERB
fnp-3025	2399	28	18f	18f	PROPN
fnp-3025	2399	29	-	-	PUNCT
fnp-3025	2399	30	florbetaben	florbetaben	PROPN
fnp-3025	2399	31	pet	pet	NOUN
fnp-3025	2399	32	.	.	PUNCT
fnp-3025	2400	1	j	j	PROPN
fnp-3025	2400	2	nucl	nucl	PROPN
fnp-3025	2400	3	med	med	PROPN
fnp-3025	2400	4	,	,	PUNCT
fnp-3025	2400	5	2013	2013	NUM
fnp-3025	2400	6	.	.	PUNCT
fnp-3025	2401	1	54(7	54(7	NUM
fnp-3025	2401	2	):	):	PUNCT
fnp-3025	2401	3	p.	p.	NOUN
fnp-3025	2401	4	1127	1127	NUM
fnp-3025	2401	5	-	-	SYM
fnp-3025	2401	6	34	34	NUM
fnp-3025	2401	7	.	.	PUNCT
fnp-3025	2401	8	470	470	NUM
fnp-3025	2401	9	.	.	PUNCT
fnp-3025	2402	1	prada	prada	NOUN
fnp-3025	2402	2	,	,	PUNCT
fnp-3025	2402	3	c.m	c.m	PROPN
fnp-3025	2402	4	.	.	PROPN
fnp-3025	2402	5	,	,	PUNCT
fnp-3025	2402	6	et	et	PROPN
fnp-3025	2402	7	al	al	PROPN
fnp-3025	2402	8	.	.	PROPN
fnp-3025	2402	9	,	,	PUNCT
fnp-3025	2402	10	antibody	antibody	NOUN
fnp-3025	2402	11	-	-	PUNCT
fnp-3025	2402	12	mediated	mediate	VERB
fnp-3025	2402	13	clearance	clearance	NOUN
fnp-3025	2402	14	of	of	ADP
fnp-3025	2402	15	amyloid	amyloid	NOUN
fnp-3025	2402	16	-	-	PUNCT
fnp-3025	2402	17	beta	beta	NOUN
fnp-3025	2402	18	peptide	peptide	NOUN
fnp-3025	2402	19	from	from	ADP
fnp-3025	2402	20	cerebral	cerebral	ADJ
fnp-3025	2402	21	amyloid	amyloid	NOUN
fnp-3025	2402	22	angiopathy	angiopathy	NOUN
fnp-3025	2402	23	revealed	reveal	VERB
fnp-3025	2402	24	by	by	ADP
fnp-3025	2402	25	quantitative	quantitative	ADJ
fnp-3025	2402	26	in	in	ADP
fnp-3025	2402	27	vivo	vivo	ADJ
fnp-3025	2402	28	imaging	imaging	NOUN
fnp-3025	2402	29	.	.	PUNCT
fnp-3025	2403	1	j	j	PROPN
fnp-3025	2403	2	neurosci	neurosci	PROPN
fnp-3025	2403	3	,	,	PUNCT
fnp-3025	2403	4	2007	2007	NUM
fnp-3025	2403	5	.	.	PUNCT
fnp-3025	2404	1	27(8	27(8	NUM
fnp-3025	2404	2	):	):	PUNCT
fnp-3025	2404	3	p.	p.	NOUN
fnp-3025	2404	4	1973	1973	NUM
fnp-3025	2404	5	-	-	SYM
fnp-3025	2404	6	80	80	NUM
fnp-3025	2404	7	.	.	PUNCT
fnp-3025	2405	1	471	471	NUM
fnp-3025	2405	2	.	.	PUNCT
fnp-3025	2406	1	okano	okano	PROPN
fnp-3025	2406	2	,	,	PUNCT
fnp-3025	2406	3	h.	h.	PROPN
fnp-3025	2406	4	and	and	CCONJ
fnp-3025	2406	5	n.	n.	PROPN
fnp-3025	2406	6	kishi	kishi	PROPN
fnp-3025	2406	7	,	,	PUNCT
fnp-3025	2406	8	investigation	investigation	NOUN
fnp-3025	2406	9	of	of	ADP
fnp-3025	2406	10	brain	brain	NOUN
fnp-3025	2406	11	science	science	NOUN
fnp-3025	2406	12	and	and	CCONJ
fnp-3025	2406	13	neurological	neurological	ADJ
fnp-3025	2406	14	/	/	SYM
fnp-3025	2406	15	psychiatric	psychiatric	ADJ
fnp-3025	2406	16	disorders	disorder	NOUN
fnp-3025	2406	17	using	use	VERB
fnp-3025	2406	18	genetically	genetically	ADV
fnp-3025	2406	19	modified	modify	VERB
fnp-3025	2406	20	non	non	ADJ
fnp-3025	2406	21	-	-	ADJ
fnp-3025	2406	22	human	human	ADJ
fnp-3025	2406	23	primates	primate	NOUN
fnp-3025	2406	24	.	.	PUNCT
fnp-3025	2407	1	curr	curr	PROPN
fnp-3025	2407	2	opin	opin	PROPN
fnp-3025	2407	3	neurobiol	neurobiol	NOUN
fnp-3025	2407	4	,	,	PUNCT
fnp-3025	2407	5	2018	2018	NUM
fnp-3025	2407	6	.	.	PUNCT
fnp-3025	2408	1	50	50	NUM
fnp-3025	2408	2	:	:	PUNCT
fnp-3025	2409	1	p.	p.	NOUN
fnp-3025	2409	2	1	1	NUM
fnp-3025	2409	3	-	-	SYM
fnp-3025	2409	4	6	6	NUM
fnp-3025	2409	5	.	.	PUNCT
fnp-3025	2409	6	472	472	NUM
fnp-3025	2409	7	.	.	PUNCT
fnp-3025	2410	1	seita	seita	PROPN
fnp-3025	2410	2	,	,	PUNCT
fnp-3025	2410	3	y.	y.	PROPN
fnp-3025	2410	4	,	,	PUNCT
fnp-3025	2410	5	et	et	PROPN
fnp-3025	2410	6	al	al	PROPN
fnp-3025	2410	7	.	.	PROPN
fnp-3025	2410	8	,	,	PUNCT
fnp-3025	2410	9	generation	generation	NOUN
fnp-3025	2410	10	of	of	ADP
fnp-3025	2410	11	transgenic	transgenic	NOUN
fnp-3025	2410	12	cynomolgus	cynomolgus	ADJ
fnp-3025	2410	13	monkeys	monkey	NOUN
fnp-3025	2410	14	overexpressing	overexpresse	VERB
fnp-3025	2410	15	the	the	DET
fnp-3025	2410	16	gene	gene	NOUN
fnp-3025	2410	17	for	for	ADP
fnp-3025	2410	18	amyloid	amyloid	NOUN
fnp-3025	2410	19	-	-	PUNCT
fnp-3025	2410	20	beta	beta	NOUN
fnp-3025	2410	21	precursor	precursor	NOUN
fnp-3025	2410	22	protein	protein	NOUN
fnp-3025	2410	23	.	.	PUNCT
fnp-3025	2411	1	j	j	PROPN
fnp-3025	2411	2	alzheimers	alzheimers	PROPN
fnp-3025	2411	3	dis	dis	PROPN
fnp-3025	2411	4	,	,	PUNCT
fnp-3025	2411	5	2020	2020	NUM
fnp-3025	2411	6	.	.	PUNCT
fnp-3025	2412	1	75(1	75(1	NUM
fnp-3025	2412	2	):	):	PUNCT
fnp-3025	2412	3	p.	p.	NOUN
fnp-3025	2412	4	45	45	NUM
fnp-3025	2412	5	-	-	SYM
fnp-3025	2412	6	60	60	NUM
fnp-3025	2412	7	.	.	PUNCT
fnp-3025	2413	1	473	473	NUM
fnp-3025	2413	2	.	.	PUNCT
fnp-3025	2413	3	vermunt	vermunt	PROPN
fnp-3025	2413	4	,	,	PUNCT
fnp-3025	2413	5	l.	l.	PROPN
fnp-3025	2413	6	,	,	PUNCT
fnp-3025	2413	7	et	et	PROPN
fnp-3025	2413	8	al	al	PROPN
fnp-3025	2413	9	.	.	PROPN
fnp-3025	2413	10	,	,	PUNCT
fnp-3025	2413	11	duration	duration	NOUN
fnp-3025	2413	12	of	of	ADP
fnp-3025	2413	13	preclinical	preclinical	ADJ
fnp-3025	2413	14	,	,	PUNCT
fnp-3025	2413	15	prodromal	prodromal	ADJ
fnp-3025	2413	16	,	,	PUNCT
fnp-3025	2413	17	and	and	CCONJ
fnp-3025	2413	18	dementia	dementia	NOUN
fnp-3025	2413	19	stages	stage	NOUN
fnp-3025	2413	20	of	of	ADP
fnp-3025	2413	21	alzheimer	alzheimer	PROPN
fnp-3025	2413	22	’s	’s	PART
fnp-3025	2413	23	disease	disease	NOUN
fnp-3025	2413	24	in	in	ADP
fnp-3025	2413	25	relation	relation	NOUN
fnp-3025	2413	26	to	to	ADP
fnp-3025	2413	27	age	age	NOUN
fnp-3025	2413	28	,	,	PUNCT
fnp-3025	2413	29	sex	sex	NOUN
fnp-3025	2413	30	,	,	PUNCT
fnp-3025	2413	31	and	and	CCONJ
fnp-3025	2413	32	apoe	apoe	ADJ
fnp-3025	2413	33	genotype	genotype	NOUN
fnp-3025	2413	34	.	.	PUNCT
fnp-3025	2414	1	alzheimers	alzheimers	PROPN
fnp-3025	2414	2	dement	dement	PROPN
fnp-3025	2414	3	,	,	PUNCT
fnp-3025	2414	4	2019	2019	NUM
fnp-3025	2414	5	.	.	PUNCT
fnp-3025	2415	1	15(7	15(7	NUM
fnp-3025	2415	2	):	):	PUNCT
fnp-3025	2416	1	p.	p.	NOUN
fnp-3025	2416	2	888	888	NUM
fnp-3025	2416	3	-	-	SYM
fnp-3025	2416	4	898	898	NUM
fnp-3025	2416	5	.	.	PUNCT
fnp-3025	2417	1	474	474	NUM
fnp-3025	2417	2	.	.	PUNCT
fnp-3025	2418	1	selkoe	selkoe	PROPN
fnp-3025	2418	2	,	,	PUNCT
fnp-3025	2418	3	d.j	d.j	AUX
fnp-3025	2418	4	.	.	PROPN
fnp-3025	2418	5	,	,	PUNCT
fnp-3025	2418	6	resolving	resolve	VERB
fnp-3025	2418	7	controversies	controversy	NOUN
fnp-3025	2418	8	on	on	ADP
fnp-3025	2418	9	the	the	DET
fnp-3025	2418	10	path	path	NOUN
fnp-3025	2418	11	to	to	ADP
fnp-3025	2418	12	alzheimer	alzheimer	PROPN
fnp-3025	2418	13	’s	’s	PART
fnp-3025	2418	14	therapeutics	therapeutic	NOUN
fnp-3025	2418	15	.	.	PUNCT
fnp-3025	2419	1	nat	nat	PROPN
fnp-3025	2419	2	med	med	PROPN
fnp-3025	2419	3	,	,	PUNCT
fnp-3025	2419	4	2011	2011	NUM
fnp-3025	2419	5	.	.	PUNCT
fnp-3025	2420	1	17(9	17(9	NOUN
fnp-3025	2420	2	):	):	PUNCT
fnp-3025	2420	3	p.	p.	NOUN
fnp-3025	2420	4	1060	1060	NUM
fnp-3025	2420	5	-	-	SYM
fnp-3025	2420	6	5	5	NUM
fnp-3025	2420	7	.	.	NOUN
fnp-3025	2420	8	475	475	NUM
fnp-3025	2420	9	.	.	PUNCT
fnp-3025	2421	1	selkoe	selkoe	PROPN
fnp-3025	2421	2	,	,	PUNCT
fnp-3025	2421	3	d.j	d.j	PROPN
fnp-3025	2421	4	.	.	PROPN
fnp-3025	2421	5	,	,	PUNCT
fnp-3025	2421	6	editorial	editorial	NOUN
fnp-3025	2421	7	:	:	PUNCT
fnp-3025	2421	8	a	a	PRON
fnp-3025	2421	9	is	be	AUX
fnp-3025	2421	10	for	for	ADP
fnp-3025	2421	11	amyloid	amyloid	NOUN
fnp-3025	2421	12	.	.	PUNCT
fnp-3025	2422	1	j	j	PROPN
fnp-3025	2422	2	prev	prev	PROPN
fnp-3025	2422	3	alzheimers	alzheimers	PROPN
fnp-3025	2422	4	dis	dis	PROPN
fnp-3025	2422	5	,	,	PUNCT
fnp-3025	2422	6	2020	2020	NUM
fnp-3025	2422	7	.	.	PUNCT
fnp-3025	2423	1	7(3	7(3	NUM
fnp-3025	2423	2	):	):	PUNCT
fnp-3025	2424	1	p.	p.	NOUN
fnp-3025	2424	2	140	140	NUM
fnp-3025	2424	3	-	-	SYM
fnp-3025	2424	4	141	141	NUM
fnp-3025	2424	5	.	.	PUNCT
fnp-3025	2425	1	476	476	NUM
fnp-3025	2425	2	.	.	PUNCT
fnp-3025	2426	1	tolar	tolar	PROPN
fnp-3025	2426	2	,	,	PUNCT
fnp-3025	2426	3	m.	m.	NOUN
fnp-3025	2426	4	,	,	PUNCT
fnp-3025	2426	5	et	et	PROPN
fnp-3025	2426	6	al	al	PROPN
fnp-3025	2426	7	.	.	PROPN
fnp-3025	2426	8	,	,	PUNCT
fnp-3025	2426	9	aducanumab	aducanumab	NOUN
fnp-3025	2426	10	,	,	PUNCT
fnp-3025	2426	11	gantenerumab	gantenerumab	NOUN
fnp-3025	2426	12	,	,	PUNCT
fnp-3025	2426	13	ban2401	ban2401	NOUN
fnp-3025	2426	14	,	,	PUNCT
fnp-3025	2426	15	and	and	CCONJ
fnp-3025	2426	16	alz-801	alz-801	NOUN
fnp-3025	2426	17	-	-	PUNCT
fnp-3025	2426	18	the	the	DET
fnp-3025	2426	19	first	first	ADJ
fnp-3025	2426	20	wave	wave	NOUN
fnp-3025	2426	21	of	of	ADP
fnp-3025	2426	22	amyloid	amyloid	NOUN
fnp-3025	2426	23	-	-	PUNCT
fnp-3025	2426	24	targeting	target	VERB
fnp-3025	2426	25	drugs	drug	NOUN
fnp-3025	2426	26	for	for	ADP
fnp-3025	2426	27	alzheimer	alzheimer	PROPN
fnp-3025	2426	28	’s	’s	PART
fnp-3025	2426	29	disease	disease	NOUN
fnp-3025	2426	30	with	with	ADP
fnp-3025	2426	31	potential	potential	NOUN
fnp-3025	2426	32	for	for	ADP
fnp-3025	2426	33	near	near	ADJ
fnp-3025	2426	34	term	term	NOUN
fnp-3025	2426	35	approval	approval	NOUN
fnp-3025	2426	36	.	.	PUNCT
fnp-3025	2427	1	alzheimers	alzheimer	NOUN
fnp-3025	2427	2	res	re	VERB
fnp-3025	2427	3	ther	ther	ADV
fnp-3025	2427	4	,	,	PUNCT
fnp-3025	2427	5	2020	2020	NUM
fnp-3025	2427	6	.	.	PUNCT
fnp-3025	2428	1	12(1	12(1	NUM
fnp-3025	2428	2	):	):	PUNCT
fnp-3025	2429	1	p.	p.	NOUN
fnp-3025	2429	2	95	95	NUM
fnp-3025	2429	3	.	.	PUNCT
fnp-3025	2430	1	477	477	NUM
fnp-3025	2430	2	.	.	PUNCT
fnp-3025	2431	1	uhlmann	uhlmann	PROPN
fnp-3025	2431	2	,	,	PUNCT
fnp-3025	2431	3	r.e	r.e	PROPN
fnp-3025	2431	4	.	.	PROPN
fnp-3025	2431	5	,	,	PUNCT
fnp-3025	2431	6	et	et	PROPN
fnp-3025	2431	7	al	al	PROPN
fnp-3025	2431	8	.	.	PROPN
fnp-3025	2431	9	,	,	PUNCT
fnp-3025	2431	10	acute	acute	PROPN
fnp-3025	2431	11	targeting	target	VERB
fnp-3025	2431	12	of	of	ADP
fnp-3025	2431	13	pre	pre	ADJ
fnp-3025	2431	14	-	-	ADJ
fnp-3025	2431	15	amyloid	amyloid	ADJ
fnp-3025	2431	16	seeds	seed	NOUN
fnp-3025	2431	17	in	in	ADP
fnp-3025	2431	18	transgenic	transgenic	NOUN
fnp-3025	2431	19	mice	mouse	NOUN
fnp-3025	2431	20	reduces	reduce	VERB
fnp-3025	2431	21	alzheimer	alzheimer	NOUN
fnp-3025	2431	22	-	-	PUNCT
fnp-3025	2431	23	like	like	ADJ
fnp-3025	2431	24	pathology	pathology	NOUN
fnp-3025	2431	25	later	later	ADV
fnp-3025	2431	26	in	in	ADP
fnp-3025	2431	27	life	life	NOUN
fnp-3025	2431	28	.	.	PUNCT
fnp-3025	2432	1	nature	nature	NOUN
fnp-3025	2432	2	neuroscience	neuroscience	NOUN
fnp-3025	2432	3	,	,	PUNCT
fnp-3025	2432	4	2020	2020	NUM
fnp-3025	2432	5	.	.	PUNCT
fnp-3025	2433	1	(	(	PUNCT
fnp-3025	2433	2	in	in	ADP
fnp-3025	2433	3	press	press	NOUN
fnp-3025	2433	4	)	)	PUNCT
fnp-3025	2433	5	.	.	PUNCT
fnp-3025	2434	1	478	478	NUM
fnp-3025	2434	2	.	.	PUNCT
fnp-3025	2434	3	holmes	holmes	PROPN
fnp-3025	2434	4	,	,	PUNCT
fnp-3025	2434	5	c.	c.	PROPN
fnp-3025	2434	6	,	,	PUNCT
fnp-3025	2434	7	et	et	PROPN
fnp-3025	2434	8	al	al	PROPN
fnp-3025	2434	9	.	.	PROPN
fnp-3025	2434	10	,	,	PUNCT
fnp-3025	2434	11	long	long	ADJ
fnp-3025	2434	12	-	-	PUNCT
fnp-3025	2434	13	term	term	NOUN
fnp-3025	2434	14	effects	effect	NOUN
fnp-3025	2434	15	of	of	ADP
fnp-3025	2434	16	abeta42	abeta42	NOUN
fnp-3025	2434	17	immunisation	immunisation	NOUN
fnp-3025	2434	18	in	in	ADP
fnp-3025	2434	19	alzheimer	alzheimer	PROPN
fnp-3025	2434	20	’s	’s	PART
fnp-3025	2434	21	disease	disease	NOUN
fnp-3025	2434	22	:	:	PUNCT
fnp-3025	2434	23	follow	follow	VERB
fnp-3025	2434	24	-	-	PUNCT
fnp-3025	2434	25	up	up	NOUN
fnp-3025	2434	26	of	of	ADP
fnp-3025	2434	27	a	a	DET
fnp-3025	2434	28	randomised	randomise	VERB
fnp-3025	2434	29	,	,	PUNCT
fnp-3025	2434	30	placebo	placebo	NOUN
fnp-3025	2434	31	-	-	PUNCT
fnp-3025	2434	32	controlled	control	VERB
fnp-3025	2434	33	phase	phase	NOUN
fnp-3025	2434	34	i	i	PRON
fnp-3025	2434	35	trial	trial	NOUN
fnp-3025	2434	36	.	.	PUNCT
fnp-3025	2435	1	lancet	lancet	PROPN
fnp-3025	2435	2	,	,	PUNCT
fnp-3025	2435	3	2008	2008	NUM
fnp-3025	2435	4	.	.	PUNCT
fnp-3025	2436	1	372(9634	372(9634	NUM
fnp-3025	2436	2	):	):	PUNCT
fnp-3025	2436	3	p.	p.	NOUN
fnp-3025	2436	4	216	216	NUM
fnp-3025	2436	5	-	-	SYM
fnp-3025	2436	6	23	23	NUM
fnp-3025	2436	7	.	.	PUNCT
fnp-3025	2437	1	479	479	NUM
fnp-3025	2437	2	.	.	PUNCT
fnp-3025	2438	1	lozupone	lozupone	NOUN
fnp-3025	2438	2	,	,	PUNCT
fnp-3025	2438	3	m.	m.	NOUN
fnp-3025	2438	4	,	,	PUNCT
fnp-3025	2438	5	et	et	PROPN
fnp-3025	2438	6	al	al	PROPN
fnp-3025	2438	7	.	.	PROPN
fnp-3025	2438	8	,	,	PUNCT
fnp-3025	2438	9	anti	anti	ADJ
fnp-3025	2438	10	-	-	ADJ
fnp-3025	2438	11	amyloid	amyloid	ADJ
fnp-3025	2438	12	-	-	PUNCT
fnp-3025	2438	13	beta	beta	NOUN
fnp-3025	2438	14	protein	protein	NOUN
fnp-3025	2438	15	agents	agent	NOUN
fnp-3025	2438	16	for	for	ADP
fnp-3025	2438	17	the	the	DET
fnp-3025	2438	18	treatment	treatment	NOUN
fnp-3025	2438	19	of	of	ADP
fnp-3025	2438	20	alzheimer	alzheimer	PROPN
fnp-3025	2438	21	’s	’s	PART
fnp-3025	2438	22	disease	disease	NOUN
fnp-3025	2438	23	:	:	PUNCT
fnp-3025	2438	24	an	an	DET
fnp-3025	2438	25	update	update	NOUN
fnp-3025	2438	26	on	on	ADP
fnp-3025	2438	27	emerging	emerge	VERB
fnp-3025	2438	28	drugs	drug	NOUN
fnp-3025	2438	29	.	.	PUNCT
fnp-3025	2439	1	expert	expert	NOUN
fnp-3025	2439	2	opin	opin	NOUN
fnp-3025	2439	3	emerg	emerg	NOUN
fnp-3025	2439	4	drugs	drug	NOUN
fnp-3025	2439	5	,	,	PUNCT
fnp-3025	2439	6	2020	2020	NUM
fnp-3025	2439	7	:	:	PUNCT
fnp-3025	2440	1	p.	p.	NOUN
fnp-3025	2440	2	1	1	NUM
fnp-3025	2440	3	-	-	SYM
fnp-3025	2440	4	17	17	NUM
fnp-3025	2440	5	.	.	PUNCT
fnp-3025	2440	6	480	480	NUM
fnp-3025	2440	7	.	.	PUNCT
fnp-3025	2441	1	clavaguera	clavaguera	PROPN
fnp-3025	2441	2	,	,	PUNCT
fnp-3025	2441	3	f.	f.	PROPN
fnp-3025	2441	4	,	,	PUNCT
fnp-3025	2441	5	c.	c.	PROPN
fnp-3025	2441	6	duyckaerts	duyckaert	NOUN
fnp-3025	2441	7	,	,	PUNCT
fnp-3025	2441	8	and	and	CCONJ
fnp-3025	2441	9	s.	s.	PROPN
fnp-3025	2441	10	haik	haik	PROPN
fnp-3025	2441	11	,	,	PUNCT
fnp-3025	2441	12	prion	prion	NOUN
fnp-3025	2441	13	-	-	PUNCT
fnp-3025	2441	14	like	like	ADJ
fnp-3025	2441	15	properties	property	NOUN
fnp-3025	2441	16	of	of	ADP
fnp-3025	2441	17	tau	tau	PROPN
fnp-3025	2441	18	assemblies	assembly	NOUN
fnp-3025	2441	19	.	.	PUNCT
fnp-3025	2442	1	curr	curr	PROPN
fnp-3025	2442	2	opin	opin	PROPN
fnp-3025	2442	3	neurobiol	neurobiol	PROPN
fnp-3025	2442	4	,	,	PUNCT
fnp-3025	2442	5	2020	2020	NUM
fnp-3025	2442	6	.	.	PUNCT
fnp-3025	2443	1	61	61	NUM
fnp-3025	2443	2	:	:	PUNCT
fnp-3025	2443	3	p.	p.	NOUN
fnp-3025	2443	4	49	49	NUM
fnp-3025	2443	5	-	-	SYM
fnp-3025	2443	6	57	57	NUM
fnp-3025	2443	7	.	.	PUNCT
fnp-3025	2444	1	481	481	NUM
fnp-3025	2444	2	.	.	PUNCT
fnp-3025	2445	1	holmes	holmes	PROPN
fnp-3025	2445	2	,	,	PUNCT
fnp-3025	2445	3	b.b	b.b	PROPN
fnp-3025	2445	4	.	.	PROPN
fnp-3025	2445	5	and	and	CCONJ
fnp-3025	2445	6	m.i	m.i	PROPN
fnp-3025	2445	7	.	.	PROPN
fnp-3025	2445	8	diamond	diamond	PROPN
fnp-3025	2445	9	,	,	PUNCT
fnp-3025	2445	10	prion	prion	NOUN
fnp-3025	2445	11	-	-	PUNCT
fnp-3025	2445	12	like	like	ADJ
fnp-3025	2445	13	properties	property	NOUN
fnp-3025	2445	14	of	of	ADP
fnp-3025	2445	15	tau	tau	PROPN
fnp-3025	2445	16	protein	protein	NOUN
fnp-3025	2445	17	:	:	PUNCT
fnp-3025	2445	18	the	the	DET
fnp-3025	2445	19	importance	importance	NOUN
fnp-3025	2445	20	of	of	ADP
fnp-3025	2445	21	extracellular	extracellular	ADJ
fnp-3025	2445	22	tau	tau	PROPN
fnp-3025	2445	23	as	as	ADP
fnp-3025	2445	24	a	a	DET
fnp-3025	2445	25	therapeutic	therapeutic	ADJ
fnp-3025	2445	26	target	target	NOUN
fnp-3025	2445	27	.	.	PUNCT
fnp-3025	2446	1	j	j	PROPN
fnp-3025	2446	2	biol	biol	PROPN
fnp-3025	2446	3	chem	chem	NOUN
fnp-3025	2446	4	,	,	PUNCT
fnp-3025	2446	5	2014	2014	NUM
fnp-3025	2446	6	.	.	PUNCT
fnp-3025	2447	1	289(29	289(29	NUM
fnp-3025	2447	2	):	):	PUNCT
fnp-3025	2447	3	p.	p.	NOUN
fnp-3025	2447	4	19855	19855	NUM
fnp-3025	2447	5	-	-	SYM
fnp-3025	2447	6	61	61	NUM
fnp-3025	2447	7	.	.	PUNCT
fnp-3025	2448	1	482	482	NUM
fnp-3025	2448	2	.	.	PUNCT
fnp-3025	2449	1	klein	klein	PROPN
fnp-3025	2449	2	,	,	PUNCT
fnp-3025	2449	3	g.	g.	PROPN
fnp-3025	2449	4	,	,	PUNCT
fnp-3025	2449	5	et	et	PROPN
fnp-3025	2449	6	al	al	PROPN
fnp-3025	2449	7	.	.	PROPN
fnp-3025	2449	8	,	,	PUNCT
fnp-3025	2449	9	gantenerumab	gantenerumab	NOUN
fnp-3025	2449	10	reduces	reduce	VERB
fnp-3025	2449	11	amyloid	amyloid	NOUN
fnp-3025	2449	12	-	-	PUNCT
fnp-3025	2449	13	beta	beta	NOUN
fnp-3025	2449	14	plaques	plaque	NOUN
fnp-3025	2449	15	in	in	ADP
fnp-3025	2449	16	patients	patient	NOUN
fnp-3025	2449	17	with	with	ADP
fnp-3025	2449	18	prodromal	prodromal	ADJ
fnp-3025	2449	19	to	to	ADP
fnp-3025	2449	20	moderate	moderate	ADJ
fnp-3025	2449	21	alzheimer	alzheimer	PROPN
fnp-3025	2449	22	’s	’s	PART
fnp-3025	2449	23	disease	disease	NOUN
fnp-3025	2449	24	:	:	PUNCT
fnp-3025	2449	25	a	a	DET
fnp-3025	2449	26	pet	pet	ADJ
fnp-3025	2449	27	substudy	substudy	ADJ
fnp-3025	2449	28	interim	interim	ADJ
fnp-3025	2449	29	analysis	analysis	NOUN
fnp-3025	2449	30	.	.	PUNCT
fnp-3025	2450	1	alzheimers	alzheimer	NOUN
fnp-3025	2450	2	res	re	VERB
fnp-3025	2450	3	ther	ther	ADV
fnp-3025	2450	4	,	,	PUNCT
fnp-3025	2450	5	2019	2019	NUM
fnp-3025	2450	6	.	.	PUNCT
fnp-3025	2451	1	11(1	11(1	NUM
fnp-3025	2451	2	):	):	PUNCT
fnp-3025	2452	1	p.	p.	NOUN
fnp-3025	2452	2	101	101	NUM
fnp-3025	2452	3	.	.	PUNCT
fnp-3025	2453	1	483	483	NUM
fnp-3025	2453	2	.	.	PUNCT
fnp-3025	2453	3	sevigny	sevigny	PROPN
fnp-3025	2453	4	,	,	PUNCT
fnp-3025	2453	5	j.	j.	PROPN
fnp-3025	2453	6	,	,	PUNCT
fnp-3025	2453	7	et	et	PROPN
fnp-3025	2453	8	al	al	PROPN
fnp-3025	2453	9	.	.	PROPN
fnp-3025	2453	10	,	,	PUNCT
fnp-3025	2453	11	the	the	DET
fnp-3025	2453	12	antibody	antibody	NOUN
fnp-3025	2453	13	aducanumab	aducanumab	NOUN
fnp-3025	2453	14	reduces	reduce	VERB
fnp-3025	2453	15	abeta	abeta	PRON
fnp-3025	2453	16	plaques	plaque	NOUN
fnp-3025	2453	17	in	in	ADP
fnp-3025	2453	18	alzheimer	alzheimer	PROPN
fnp-3025	2453	19	’s	’s	PART
fnp-3025	2453	20	disease	disease	NOUN
fnp-3025	2453	21	.	.	PUNCT
fnp-3025	2454	1	nature	nature	NOUN
fnp-3025	2454	2	,	,	PUNCT
fnp-3025	2454	3	2016	2016	NUM
fnp-3025	2454	4	.	.	PUNCT
fnp-3025	2455	1	537(7618	537(7618	NUM
fnp-3025	2455	2	):	):	PUNCT
fnp-3025	2456	1	p.	p.	NOUN
fnp-3025	2456	2	50	50	NUM
fnp-3025	2456	3	-	-	SYM
fnp-3025	2456	4	6	6	NUM
fnp-3025	2456	5	.	.	PUNCT
fnp-3025	2456	6	484	484	NUM
fnp-3025	2456	7	.	.	PUNCT
fnp-3025	2457	1	selkoe	selkoe	PROPN
fnp-3025	2457	2	,	,	PUNCT
fnp-3025	2457	3	d.j	d.j	PROPN
fnp-3025	2457	4	.	.	PROPN
fnp-3025	2457	5	and	and	CCONJ
fnp-3025	2457	6	j.	j.	PROPN
fnp-3025	2457	7	hardy	hardy	PROPN
fnp-3025	2457	8	,	,	PUNCT
fnp-3025	2457	9	the	the	DET
fnp-3025	2457	10	amyloid	amyloid	NOUN
fnp-3025	2457	11	hypothesis	hypothesis	NOUN
fnp-3025	2457	12	of	of	ADP
fnp-3025	2457	13	alzheimer	alzheimer	PROPN
fnp-3025	2457	14	’s	’s	PART
fnp-3025	2457	15	disease	disease	NOUN
fnp-3025	2457	16	at	at	ADP
fnp-3025	2457	17	25	25	NUM
fnp-3025	2457	18	years	year	NOUN
fnp-3025	2457	19	.	.	PUNCT
fnp-3025	2458	1	embo	embo	NOUN
fnp-3025	2458	2	mol	mol	ADP
fnp-3025	2458	3	med	med	PROPN
fnp-3025	2458	4	,	,	PUNCT
fnp-3025	2458	5	2016	2016	NUM
fnp-3025	2458	6	.	.	PUNCT
fnp-3025	2458	7	8(6	8(6	NUM
fnp-3025	2458	8	):	):	PUNCT
fnp-3025	2458	9	p.	p.	NOUN
fnp-3025	2458	10	595	595	NUM
fnp-3025	2458	11	-	-	SYM
fnp-3025	2458	12	608	608	NUM
fnp-3025	2458	13	.	.	PUNCT
fnp-3025	2458	14	485	485	NUM
fnp-3025	2458	15	.	.	X
fnp-3025	2459	1	angelucci	angelucci	PROPN
fnp-3025	2459	2	,	,	PUNCT
fnp-3025	2459	3	f.	f.	PROPN
fnp-3025	2459	4	,	,	PUNCT
fnp-3025	2459	5	et	et	PROPN
fnp-3025	2459	6	al	al	PROPN
fnp-3025	2459	7	.	.	PROPN
fnp-3025	2459	8	,	,	PUNCT
fnp-3025	2459	9	antibiotics	antibiotic	NOUN
fnp-3025	2459	10	,	,	PUNCT
fnp-3025	2459	11	gut	gut	NOUN
fnp-3025	2459	12	microbiota	microbiota	NOUN
fnp-3025	2459	13	,	,	PUNCT
fnp-3025	2459	14	and	and	CCONJ
fnp-3025	2459	15	alzheimer	alzheimer	PROPN
fnp-3025	2459	16	’s	’s	PART
fnp-3025	2459	17	disease	disease	NOUN
fnp-3025	2459	18	.	.	PUNCT
fnp-3025	2460	1	j	j	PROPN
fnp-3025	2460	2	neuroinflammation	neuroinflammation	PROPN
fnp-3025	2460	3	,	,	PUNCT
fnp-3025	2460	4	2019	2019	NUM
fnp-3025	2460	5	.	.	PUNCT
fnp-3025	2461	1	16(1	16(1	NUM
fnp-3025	2461	2	):	):	PUNCT
fnp-3025	2461	3	p.	p.	NOUN
fnp-3025	2461	4	108	108	NUM
fnp-3025	2461	5	.	.	PUNCT
fnp-3025	2462	1	486	486	NUM
fnp-3025	2462	2	.	.	PUNCT
fnp-3025	2463	1	sureda	sureda	PROPN
fnp-3025	2463	2	,	,	PUNCT
fnp-3025	2463	3	a.	a.	NOUN
fnp-3025	2463	4	,	,	PUNCT
fnp-3025	2463	5	et	et	PROPN
fnp-3025	2463	6	al	al	PROPN
fnp-3025	2463	7	.	.	PROPN
fnp-3025	2463	8	,	,	PUNCT
fnp-3025	2463	9	oral	oral	ADJ
fnp-3025	2463	10	microbiota	microbiota	NOUN
fnp-3025	2463	11	and	and	CCONJ
fnp-3025	2463	12	alzheimer	alzheimer	NOUN
fnp-3025	2463	13	’s	’s	PART
fnp-3025	2463	14	disease	disease	NOUN
fnp-3025	2463	15	:	:	PUNCT
fnp-3025	2463	16	do	do	AUX
fnp-3025	2463	17	all	all	DET
fnp-3025	2463	18	roads	road	NOUN
fnp-3025	2463	19	lead	lead	VERB
fnp-3025	2463	20	to	to	ADP
fnp-3025	2463	21	rome	rome	PROPN
fnp-3025	2463	22	?	?	PUNCT
fnp-3025	2464	1	pharmacol	pharmacol	PROPN
fnp-3025	2464	2	res	re	NOUN
fnp-3025	2464	3	,	,	PUNCT
fnp-3025	2464	4	2020	2020	NUM
fnp-3025	2464	5	.	.	PUNCT
fnp-3025	2465	1	151	151	NUM
fnp-3025	2465	2	:	:	PUNCT
fnp-3025	2466	1	p.	p.	NOUN
fnp-3025	2466	2	104582	104582	NUM
fnp-3025	2466	3	.	.	PUNCT
fnp-3025	2467	1	487	487	NUM
fnp-3025	2467	2	.	.	X
fnp-3025	2468	1	lemere	lemere	PROPN
fnp-3025	2468	2	,	,	PUNCT
fnp-3025	2468	3	c.a	c.a	PROPN
fnp-3025	2468	4	.	.	PROPN
fnp-3025	2468	5	,	,	PUNCT
fnp-3025	2468	6	immunotherapy	immunotherapy	NOUN
fnp-3025	2468	7	for	for	ADP
fnp-3025	2468	8	alzheimer	alzheimer	PROPN
fnp-3025	2468	9	’s	’s	PART
fnp-3025	2468	10	disease	disease	NOUN
fnp-3025	2468	11	:	:	PUNCT
fnp-3025	2468	12	hoops	hoop	NOUN
fnp-3025	2468	13	and	and	CCONJ
fnp-3025	2468	14	hurdles	hurdle	NOUN
fnp-3025	2468	15	.	.	PUNCT
fnp-3025	2469	1	mol	mol	ADP
fnp-3025	2469	2	neurodegener	neurodegener	NOUN
fnp-3025	2469	3	,	,	PUNCT
fnp-3025	2469	4	2013	2013	NUM
fnp-3025	2469	5	.	.	PUNCT
fnp-3025	2470	1	8	8	NUM
fnp-3025	2470	2	:	:	PUNCT
fnp-3025	2470	3	p.	p.	NOUN
fnp-3025	2470	4	36	36	NUM
fnp-3025	2470	5	.	.	PUNCT
fnp-3025	2470	6	488	488	NUM
fnp-3025	2470	7	.	.	PUNCT
fnp-3025	2471	1	van	van	PROPN
fnp-3025	2471	2	dyck	dyck	PROPN
fnp-3025	2471	3	,	,	PUNCT
fnp-3025	2471	4	c.h	c.h	PROPN
fnp-3025	2471	5	.	.	PROPN
fnp-3025	2471	6	,	,	PUNCT
fnp-3025	2471	7	anti	anti	ADJ
fnp-3025	2471	8	-	-	ADJ
fnp-3025	2471	9	amyloid	amyloid	ADJ
fnp-3025	2471	10	-	-	PUNCT
fnp-3025	2471	11	beta	beta	NOUN
fnp-3025	2471	12	monoclonal	monoclonal	NOUN
fnp-3025	2471	13	antibodies	antibody	NOUN
fnp-3025	2471	14	for	for	ADP
fnp-3025	2471	15	alzheimer	alzheimer	PROPN
fnp-3025	2471	16	’s	’s	PART
fnp-3025	2471	17	disease	disease	NOUN
fnp-3025	2471	18	:	:	PUNCT
fnp-3025	2471	19	pitfalls	pitfall	NOUN
fnp-3025	2471	20	and	and	CCONJ
fnp-3025	2471	21	promise	promise	NOUN
fnp-3025	2471	22	.	.	PUNCT
fnp-3025	2472	1	biol	biol	PROPN
fnp-3025	2472	2	psychiatry	psychiatry	NOUN
fnp-3025	2472	3	,	,	PUNCT
fnp-3025	2472	4	2018	2018	NUM
fnp-3025	2472	5	.	.	PUNCT
fnp-3025	2473	1	83(4	83(4	NUM
fnp-3025	2473	2	):	):	PUNCT
fnp-3025	2474	1	p.	p.	NOUN
fnp-3025	2474	2	311	311	NUM
fnp-3025	2474	3	-	-	SYM
fnp-3025	2474	4	319	319	NUM
fnp-3025	2474	5	.	.	PUNCT
fnp-3025	2474	6	489	489	NUM
fnp-3025	2474	7	.	.	PUNCT
fnp-3025	2475	1	voytyuk	voytyuk	NOUN
fnp-3025	2475	2	,	,	PUNCT
fnp-3025	2475	3	i.	i.	PROPN
fnp-3025	2475	4	,	,	PUNCT
fnp-3025	2475	5	b.	b.	PROPN
fnp-3025	2475	6	de	de	PROPN
fnp-3025	2475	7	strooper	strooper	PROPN
fnp-3025	2475	8	,	,	PUNCT
fnp-3025	2475	9	and	and	CCONJ
fnp-3025	2475	10	l.	l.	PROPN
fnp-3025	2475	11	chavez	chavez	PROPN
fnp-3025	2475	12	-	-	PUNCT
fnp-3025	2475	13	gutierrez	gutierrez	PROPN
fnp-3025	2475	14	,	,	PUNCT
fnp-3025	2475	15	modulation	modulation	NOUN
fnp-3025	2475	16	of	of	ADP
fnp-3025	2475	17	gammaand	gammaand	NOUN
fnp-3025	2475	18	beta	beta	NOUN
fnp-3025	2475	19	-	-	PUNCT
fnp-3025	2475	20	secretases	secretase	NOUN
fnp-3025	2475	21	as	as	ADP
fnp-3025	2475	22	early	early	ADJ
fnp-3025	2475	23	prevention	prevention	NOUN
fnp-3025	2475	24	against	against	ADP
fnp-3025	2475	25	alzheimer	alzheimer	PROPN
fnp-3025	2475	26	’s	’s	PART
fnp-3025	2475	27	disease	disease	NOUN
fnp-3025	2475	28	.	.	PUNCT
fnp-3025	2476	1	biol	biol	PROPN
fnp-3025	2476	2	psychiatry	psychiatry	NOUN
fnp-3025	2476	3	,	,	PUNCT
fnp-3025	2476	4	2018	2018	NUM
fnp-3025	2476	5	.	.	PUNCT
fnp-3025	2477	1	83(4	83(4	NUM
fnp-3025	2477	2	):	):	PUNCT
fnp-3025	2478	1	p.	p.	NOUN
fnp-3025	2478	2	320	320	NUM
fnp-3025	2478	3	-	-	SYM
fnp-3025	2478	4	327	327	NUM
fnp-3025	2478	5	.	.	PUNCT
fnp-3025	2478	6	490	490	NUM
fnp-3025	2478	7	.	.	PUNCT
fnp-3025	2479	1	wisniewski	wisniewski	PROPN
fnp-3025	2479	2	,	,	PUNCT
fnp-3025	2479	3	t.	t.	PROPN
fnp-3025	2479	4	and	and	CCONJ
fnp-3025	2479	5	f.	f.	PROPN
fnp-3025	2479	6	goni	goni	PROPN
fnp-3025	2479	7	,	,	PUNCT
fnp-3025	2479	8	immunotherapeutic	immunotherapeutic	ADJ
fnp-3025	2479	9	approaches	approach	NOUN
fnp-3025	2479	10	for	for	ADP
fnp-3025	2479	11	alzheimer	alzheimer	PROPN
fnp-3025	2479	12	’s	’s	PART
fnp-3025	2479	13	disease	disease	NOUN
fnp-3025	2479	14	.	.	PUNCT
fnp-3025	2480	1	neuron	neuron	PROPN
fnp-3025	2480	2	,	,	PUNCT
fnp-3025	2480	3	2015	2015	NUM
fnp-3025	2480	4	.	.	PUNCT
fnp-3025	2481	1	85(6	85(6	NUM
fnp-3025	2481	2	):	):	PUNCT
fnp-3025	2481	3	p.	p.	NOUN
fnp-3025	2481	4	1162	1162	NUM
fnp-3025	2481	5	-	-	SYM
fnp-3025	2481	6	76	76	NUM
fnp-3025	2481	7	.	.	PUNCT
fnp-3025	2482	1	491	491	NUM
fnp-3025	2482	2	.	.	PUNCT
fnp-3025	2483	1	plotkin	plotkin	PROPN
fnp-3025	2483	2	,	,	PUNCT
fnp-3025	2483	3	s.s	s.s	PROPN
fnp-3025	2483	4	.	.	PROPN
fnp-3025	2483	5	and	and	CCONJ
fnp-3025	2483	6	n.r	n.r	PROPN
fnp-3025	2483	7	.	.	PROPN
fnp-3025	2483	8	cashman	cashman	PROPN
fnp-3025	2483	9	,	,	PUNCT
fnp-3025	2483	10	passive	passive	ADJ
fnp-3025	2483	11	immunotherapies	immunotherapy	NOUN
fnp-3025	2483	12	targeting	target	VERB
fnp-3025	2483	13	abeta	abeta	ADV
fnp-3025	2483	14	and	and	CCONJ
fnp-3025	2483	15	tau	tau	PROPN
fnp-3025	2483	16	in	in	ADP
fnp-3025	2483	17	alzheimer	alzheimer	PROPN
fnp-3025	2483	18	’s	’s	PART
fnp-3025	2483	19	disease	disease	NOUN
fnp-3025	2483	20	.	.	PUNCT
fnp-3025	2484	1	neurobiol	neurobiol	PROPN
fnp-3025	2484	2	dis	dis	PROPN
fnp-3025	2484	3	,	,	PUNCT
fnp-3025	2484	4	2020	2020	NUM
fnp-3025	2484	5	.	.	PUNCT
fnp-3025	2485	1	144	144	NUM
fnp-3025	2485	2	:	:	PUNCT
fnp-3025	2485	3	p.	p.	NOUN
fnp-3025	2485	4	105010	105010	NUM
fnp-3025	2485	5	.	.	PUNCT
fnp-3025	2486	1	492	492	NUM
fnp-3025	2486	2	.	.	PUNCT
fnp-3025	2487	1	kwon	kwon	PROPN
fnp-3025	2487	2	,	,	PUNCT
fnp-3025	2487	3	s.	s.	PROPN
fnp-3025	2487	4	,	,	PUNCT
fnp-3025	2487	5	et	et	PROPN
fnp-3025	2487	6	al	al	PROPN
fnp-3025	2487	7	.	.	PROPN
fnp-3025	2487	8	,	,	PUNCT
fnp-3025	2487	9	immunotherapies	immunotherapy	NOUN
fnp-3025	2487	10	for	for	ADP
fnp-3025	2487	11	aging	age	VERB
fnp-3025	2487	12	-	-	PUNCT
fnp-3025	2487	13	related	relate	VERB
fnp-3025	2487	14	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2487	15	diseases	disease	NOUN
fnp-3025	2487	16	-	-	PUNCT
fnp-3025	2487	17	emerging	emerge	VERB
fnp-3025	2487	18	perspectives	perspective	NOUN
fnp-3025	2487	19	and	and	CCONJ
fnp-3025	2487	20	new	new	ADJ
fnp-3025	2487	21	targets	target	NOUN
fnp-3025	2487	22	.	.	PUNCT
fnp-3025	2488	1	neurotherapeutics	neurotherapeutic	NOUN
fnp-3025	2488	2	,	,	PUNCT
fnp-3025	2488	3	2020	2020	NUM
fnp-3025	2488	4	.	.	PUNCT
fnp-3025	2489	1	p.	p.	NOUN
fnp-3025	2489	2	1	1	NUM
fnp-3025	2489	3	-	-	SYM
fnp-3025	2489	4	20	20	NUM
fnp-3025	2489	5	.	.	PUNCT
fnp-3025	2489	6	493	493	NUM
fnp-3025	2489	7	.	.	PUNCT
fnp-3025	2490	1	yu	yu	PROPN
fnp-3025	2490	2	,	,	PUNCT
fnp-3025	2490	3	y.j	y.j	PROPN
fnp-3025	2490	4	.	.	PROPN
fnp-3025	2490	5	and	and	CCONJ
fnp-3025	2490	6	r.j	r.j	PROPN
fnp-3025	2490	7	.	.	PROPN
fnp-3025	2490	8	watts	watts	PROPN
fnp-3025	2490	9	,	,	PUNCT
fnp-3025	2490	10	developing	develop	VERB
fnp-3025	2490	11	therapeutic	therapeutic	ADJ
fnp-3025	2490	12	antibodies	antibody	NOUN
fnp-3025	2490	13	for	for	ADP
fnp-3025	2490	14	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2490	15	disease	disease	NOUN
fnp-3025	2490	16	.	.	PUNCT
fnp-3025	2491	1	neurotherapeutics	neurotherapeutic	NOUN
fnp-3025	2491	2	,	,	PUNCT
fnp-3025	2491	3	2013	2013	NUM
fnp-3025	2491	4	.	.	PUNCT
fnp-3025	2492	1	10(3	10(3	NUM
fnp-3025	2492	2	):	):	PUNCT
fnp-3025	2492	3	p.	p.	NOUN
fnp-3025	2492	4	459	459	NUM
fnp-3025	2492	5	-	-	SYM
fnp-3025	2492	6	72	72	NUM
fnp-3025	2492	7	.	.	PUNCT
fnp-3025	2493	1	494	494	NUM
fnp-3025	2493	2	.	.	X
fnp-3025	2493	3	bennett	bennett	PROPN
fnp-3025	2493	4	,	,	PUNCT
fnp-3025	2493	5	c.f	c.f	PROPN
fnp-3025	2493	6	.	.	PROPN
fnp-3025	2493	7	,	,	PUNCT
fnp-3025	2493	8	a.r	a.r	PROPN
fnp-3025	2493	9	.	.	PROPN
fnp-3025	2493	10	krainer	krainer	NOUN
fnp-3025	2493	11	,	,	PUNCT
fnp-3025	2493	12	and	and	CCONJ
fnp-3025	2493	13	d.w	d.w	PROPN
fnp-3025	2493	14	.	.	PROPN
fnp-3025	2493	15	cleveland	cleveland	PROPN
fnp-3025	2493	16	,	,	PUNCT
fnp-3025	2493	17	antisense	antisense	NOUN
fnp-3025	2493	18	oligonucleotide	oligonucleotide	NOUN
fnp-3025	2493	19	therapies	therapy	NOUN
fnp-3025	2493	20	for	for	ADP
fnp-3025	2493	21	neurodegenerative	neurodegenerative	ADJ
fnp-3025	2493	22	diseases	disease	NOUN
fnp-3025	2493	23	.	.	PUNCT
fnp-3025	2494	1	annu	annu	PROPN
fnp-3025	2494	2	rev	rev	PROPN
fnp-3025	2494	3	neurosci	neurosci	PROPN
fnp-3025	2494	4	,	,	PUNCT
fnp-3025	2494	5	2019	2019	NUM
fnp-3025	2494	6	.	.	PUNCT
fnp-3025	2495	1	42	42	NUM
fnp-3025	2495	2	:	:	PUNCT
fnp-3025	2496	1	p.	p.	NOUN
fnp-3025	2496	2	385	385	NUM
fnp-3025	2496	3	-	-	SYM
fnp-3025	2496	4	406	406	NUM
fnp-3025	2496	5	.	.	PUNCT
fnp-3025	2496	6	495	495	NUM
fnp-3025	2496	7	.	.	PUNCT
fnp-3025	2497	1	chakravarthy	chakravarthy	ADJ
fnp-3025	2497	2	,	,	PUNCT
fnp-3025	2497	3	m.	m.	NOUN
fnp-3025	2497	4	,	,	PUNCT
fnp-3025	2497	5	et	et	PROPN
fnp-3025	2497	6	al	al	PROPN
fnp-3025	2497	7	.	.	PROPN
fnp-3025	2497	8	,	,	PUNCT
fnp-3025	2497	9	nucleic	nucleic	ADJ
fnp-3025	2497	10	acid	acid	NOUN
fnp-3025	2497	11	-	-	PUNCT
fnp-3025	2497	12	based	base	VERB
fnp-3025	2497	13	theranostics	theranostic	NOUN
fnp-3025	2497	14	for	for	ADP
fnp-3025	2497	15	tackling	tackle	VERB
fnp-3025	2497	16	alzheimer	alzheimer	NOUN
fnp-3025	2497	17	’s	’s	PART
fnp-3025	2497	18	disease	disease	NOUN
fnp-3025	2497	19	.	.	PUNCT
fnp-3025	2498	1	theranostics	theranostic	NOUN
fnp-3025	2498	2	,	,	PUNCT
fnp-3025	2498	3	2017	2017	NUM
fnp-3025	2498	4	.	.	PUNCT
fnp-3025	2499	1	7(16	7(16	NUM
fnp-3025	2499	2	):	):	PUNCT
fnp-3025	2499	3	p.	p.	NOUN
fnp-3025	2499	4	3933	3933	NUM
fnp-3025	2499	5	-	-	SYM
fnp-3025	2499	6	3947	3947	NUM
fnp-3025	2499	7	.	.	PUNCT
fnp-3025	2500	1	496	496	NUM
fnp-3025	2500	2	.	.	PUNCT
fnp-3025	2501	1	kim	kim	PROPN
fnp-3025	2501	2	,	,	PUNCT
fnp-3025	2501	3	k.s	k.s	PROPN
fnp-3025	2501	4	.	.	PROPN
fnp-3025	2501	5	,	,	PUNCT
fnp-3025	2501	6	et	et	PROPN
fnp-3025	2501	7	al	al	PROPN
fnp-3025	2501	8	.	.	PROPN
fnp-3025	2501	9	,	,	PUNCT
fnp-3025	2501	10	production	production	NOUN
fnp-3025	2501	11	and	and	CCONJ
fnp-3025	2501	12	characterization	characterization	NOUN
fnp-3025	2501	13	of	of	ADP
fnp-3025	2501	14	monoclonal	monoclonal	NOUN
fnp-3025	2501	15	antibodies	antibody	NOUN
fnp-3025	2501	16	reactive	reactive	ADJ
fnp-3025	2501	17	to	to	PART
fnp-3025	2501	18	synthetic	synthetic	VERB
fnp-3025	2501	19	cerebrovascular	cerebrovascular	ADJ
fnp-3025	2501	20	amyloid	amyloid	NOUN
fnp-3025	2501	21	peptide	peptide	NOUN
fnp-3025	2501	22	.	.	PUNCT
fnp-3025	2502	1	neurosci	neurosci	PROPN
fnp-3025	2502	2	res	res	PROPN
fnp-3025	2502	3	commun	commun	PROPN
fnp-3025	2502	4	,	,	PUNCT
fnp-3025	2502	5	1988	1988	NUM
fnp-3025	2502	6	.	.	PUNCT
fnp-3025	2503	1	2	2	NUM
fnp-3025	2503	2	:	:	PUNCT
fnp-3025	2503	3	p.	p.	NOUN
fnp-3025	2503	4	121	121	NUM
fnp-3025	2503	5	-	-	SYM
fnp-3025	2503	6	130	130	NUM
fnp-3025	2503	7	.	.	PUNCT
fnp-3025	2503	8	497	497	NUM
fnp-3025	2503	9	.	.	PUNCT
fnp-3025	2504	1	potempska	potempska	PROPN
fnp-3025	2504	2	,	,	PUNCT
fnp-3025	2504	3	a.	a.	PROPN
fnp-3025	2504	4	,	,	PUNCT
fnp-3025	2504	5	et	et	PROPN
fnp-3025	2504	6	al	al	PROPN
fnp-3025	2504	7	.	.	PROPN
fnp-3025	2504	8	,	,	PUNCT
fnp-3025	2504	9	quantification	quantification	NOUN
fnp-3025	2504	10	of	of	ADP
fnp-3025	2504	11	sub	sub	ADJ
fnp-3025	2504	12	-	-	ADJ
fnp-3025	2504	13	femtomole	femtomole	ADJ
fnp-3025	2504	14	amounts	amount	NOUN
fnp-3025	2504	15	of	of	ADP
fnp-3025	2504	16	alzheimer	alzheimer	PROPN
fnp-3025	2504	17	amyloid	amyloid	NOUN
fnp-3025	2504	18	beta	beta	NOUN
fnp-3025	2504	19	peptides	peptide	NOUN
fnp-3025	2504	20	.	.	PUNCT
fnp-3025	2505	1	amyloid	amyloid	NOUN
fnp-3025	2505	2	,	,	PUNCT
fnp-3025	2505	3	1999	1999	NUM
fnp-3025	2505	4	.	.	PUNCT
fnp-3025	2506	1	6(1	6(1	NUM
fnp-3025	2506	2	):	):	PUNCT
fnp-3025	2507	1	p.	p.	NOUN
fnp-3025	2507	2	14	14	NUM
fnp-3025	2507	3	-	-	SYM
fnp-3025	2507	4	21	21	NUM
fnp-3025	2507	5	.	.	PUNCT
fnp-3025	2507	6	498	498	NUM
fnp-3025	2507	7	.	.	PUNCT
fnp-3025	2508	1	horikoshi	horikoshi	PROPN
fnp-3025	2508	2	,	,	PUNCT
fnp-3025	2508	3	y.	y.	PROPN
fnp-3025	2508	4	,	,	PUNCT
fnp-3025	2508	5	et	et	PROPN
fnp-3025	2508	6	al	al	PROPN
fnp-3025	2508	7	.	.	PROPN
fnp-3025	2508	8	,	,	PUNCT
fnp-3025	2508	9	development	development	NOUN
fnp-3025	2508	10	of	of	ADP
fnp-3025	2508	11	abeta	abeta	PROPN
fnp-3025	2508	12	terminal	terminal	PROPN
fnp-3025	2508	13	end	end	NOUN
fnp-3025	2508	14	-	-	PUNCT
fnp-3025	2508	15	specific	specific	ADJ
fnp-3025	2508	16	antibodies	antibody	NOUN
fnp-3025	2508	17	and	and	CCONJ
fnp-3025	2508	18	sensitive	sensitive	ADJ
fnp-3025	2508	19	elisa	elisa	NOUN
fnp-3025	2508	20	for	for	ADP
fnp-3025	2508	21	abeta	abeta	NOUN
fnp-3025	2508	22	variant	variant	NOUN
fnp-3025	2508	23	.	.	PUNCT
fnp-3025	2509	1	biochem	biochem	PROPN
fnp-3025	2509	2	biophys	biophys	PROPN
fnp-3025	2509	3	res	re	NOUN
fnp-3025	2509	4	commun	commun	PROPN
fnp-3025	2509	5	,	,	PUNCT
fnp-3025	2509	6	2004	2004	NUM
fnp-3025	2509	7	.	.	PUNCT
fnp-3025	2510	1	319(3	319(3	NUM
fnp-3025	2510	2	):	):	PUNCT
fnp-3025	2510	3	p.	p.	NOUN
fnp-3025	2510	4	733	733	NUM
fnp-3025	2510	5	-	-	SYM
fnp-3025	2510	6	7	7	NUM
fnp-3025	2510	7	.	.	NUM
fnp-3025	2510	8	499	499	NUM
fnp-3025	2510	9	.	.	PUNCT
fnp-3025	2511	1	duff	duff	PROPN
fnp-3025	2511	2	,	,	PUNCT
fnp-3025	2511	3	k.	k.	PROPN
fnp-3025	2511	4	,	,	PUNCT
fnp-3025	2511	5	et	et	PROPN
fnp-3025	2511	6	al	al	PROPN
fnp-3025	2511	7	.	.	PROPN
fnp-3025	2511	8	,	,	PUNCT
fnp-3025	2511	9	characterization	characterization	NOUN
fnp-3025	2511	10	of	of	ADP
fnp-3025	2511	11	pathology	pathology	NOUN
fnp-3025	2511	12	in	in	ADP
fnp-3025	2511	13	transgenic	transgenic	NOUN
fnp-3025	2511	14	mice	mouse	NOUN
fnp-3025	2511	15	over	over	ADP
fnp-3025	2511	16	-	-	PUNCT
fnp-3025	2511	17	expressing	express	VERB
fnp-3025	2511	18	human	human	ADJ
fnp-3025	2511	19	genomic	genomic	NOUN
fnp-3025	2511	20	and	and	CCONJ
fnp-3025	2511	21	cdna	cdna	PROPN
fnp-3025	2511	22	tau	tau	PROPN
fnp-3025	2511	23	transgenes	transgene	NOUN
fnp-3025	2511	24	.	.	PUNCT
fnp-3025	2512	1	neurobiol	neurobiol	PROPN
fnp-3025	2512	2	dis	dis	PROPN
fnp-3025	2512	3	,	,	PUNCT
fnp-3025	2512	4	2000	2000	NUM
fnp-3025	2512	5	.	.	PUNCT
fnp-3025	2513	1	7(2	7(2	NUM
fnp-3025	2513	2	):	):	PUNCT
fnp-3025	2514	1	p.	p.	NOUN
fnp-3025	2514	2	87	87	NUM
fnp-3025	2514	3	-	-	SYM
fnp-3025	2514	4	98	98	NUM
fnp-3025	2514	5	.	.	PUNCT
fnp-3025	2514	6	500	500	NUM
fnp-3025	2514	7	.	.	PUNCT
fnp-3025	2515	1	jicha	jicha	PROPN
fnp-3025	2515	2	,	,	PUNCT
fnp-3025	2515	3	g.a	g.a	PROPN
fnp-3025	2515	4	.	.	PROPN
fnp-3025	2515	5	,	,	PUNCT
fnp-3025	2515	6	et	et	PROPN
fnp-3025	2515	7	al	al	PROPN
fnp-3025	2515	8	.	.	PROPN
fnp-3025	2515	9	,	,	PUNCT
fnp-3025	2515	10	alz-50	alz-50	ADV
fnp-3025	2515	11	and	and	CCONJ
fnp-3025	2515	12	mc-1	mc-1	NOUN
fnp-3025	2515	13	,	,	PUNCT
fnp-3025	2515	14	a	a	DET
fnp-3025	2515	15	new	new	ADJ
fnp-3025	2515	16	monoclonal	monoclonal	NOUN
fnp-3025	2515	17	antibody	antibody	NOUN
fnp-3025	2515	18	raised	raise	VERB
fnp-3025	2515	19	to	to	ADP
fnp-3025	2515	20	paired	pair	VERB
fnp-3025	2515	21	helical	helical	ADJ
fnp-3025	2515	22	filaments	filament	NOUN
fnp-3025	2515	23	,	,	PUNCT
fnp-3025	2515	24	recognize	recognize	VERB
fnp-3025	2515	25	conformational	conformational	ADJ
fnp-3025	2515	26	epitopes	epitope	NOUN
fnp-3025	2515	27	on	on	ADP
fnp-3025	2515	28	recombinant	recombinant	ADJ
fnp-3025	2515	29	tau	tau	PROPN
fnp-3025	2515	30	.	.	PUNCT
fnp-3025	2516	1	j	j	PROPN
fnp-3025	2516	2	neurosci	neurosci	PROPN
fnp-3025	2516	3	res	re	NOUN
fnp-3025	2516	4	,	,	PUNCT
fnp-3025	2516	5	1997	1997	NUM
fnp-3025	2516	6	.	.	PUNCT
fnp-3025	2517	1	48(2	48(2	NUM
fnp-3025	2517	2	):	):	PUNCT
fnp-3025	2518	1	p.	p.	NOUN
fnp-3025	2518	2	128	128	NUM
fnp-3025	2518	3	-	-	SYM
fnp-3025	2518	4	32	32	NUM
fnp-3025	2518	5	.	.	PUNCT
fnp-3025	2518	6	501	501	NUM
fnp-3025	2518	7	.	.	PUNCT
fnp-3025	2519	1	imai	imai	PROPN
fnp-3025	2519	2	,	,	PUNCT
fnp-3025	2519	3	y.	y.	PROPN
fnp-3025	2519	4	,	,	PUNCT
fnp-3025	2519	5	et	et	PROPN
fnp-3025	2519	6	al	al	PROPN
fnp-3025	2519	7	.	.	PROPN
fnp-3025	2519	8	,	,	PUNCT
fnp-3025	2519	9	a	a	DET
fnp-3025	2519	10	novel	novel	ADJ
fnp-3025	2519	11	gene	gene	NOUN
fnp-3025	2519	12	iba1	iba1	NOUN
fnp-3025	2519	13	in	in	ADP
fnp-3025	2519	14	the	the	DET
fnp-3025	2519	15	major	major	ADJ
fnp-3025	2519	16	histocompatibility	histocompatibility	NOUN
fnp-3025	2519	17	complex	complex	ADJ
fnp-3025	2519	18	class	class	NOUN
fnp-3025	2519	19	iii	iii	NOUN
fnp-3025	2519	20	region	region	NOUN
fnp-3025	2519	21	encoding	encode	VERB
fnp-3025	2519	22	an	an	DET
fnp-3025	2519	23	ef	ef	PROPN
fnp-3025	2519	24	hand	hand	NOUN
fnp-3025	2519	25	protein	protein	NOUN
fnp-3025	2519	26	expressed	express	VERB
fnp-3025	2519	27	in	in	ADP
fnp-3025	2519	28	a	a	DET
fnp-3025	2519	29	monocytic	monocytic	ADJ
fnp-3025	2519	30	lineage	lineage	NOUN
fnp-3025	2519	31	.	.	PUNCT
fnp-3025	2520	1	biochem	biochem	PROPN
fnp-3025	2520	2	biophys	biophy	VERB
fnp-3025	2520	3	res	re	NOUN
fnp-3025	2520	4	commun	commun	PROPN
fnp-3025	2520	5	,	,	PUNCT
fnp-3025	2520	6	1996	1996	NUM
fnp-3025	2520	7	.	.	PUNCT
fnp-3025	2521	1	224(3	224(3	NUM
fnp-3025	2521	2	):	):	PUNCT
fnp-3025	2521	3	p.	p.	NOUN
fnp-3025	2521	4	855	855	NUM
fnp-3025	2521	5	-	-	SYM
fnp-3025	2521	6	62	62	NUM
fnp-3025	2521	7	.	.	PUNCT
fnp-3025	2522	1	502	502	NUM
fnp-3025	2522	2	.	.	PUNCT
fnp-3025	2523	1	ito	ito	PROPN
fnp-3025	2523	2	,	,	PUNCT
fnp-3025	2523	3	d.	d.	PROPN
fnp-3025	2523	4	,	,	PUNCT
fnp-3025	2523	5	et	et	PROPN
fnp-3025	2523	6	al	al	PROPN
fnp-3025	2523	7	.	.	PROPN
fnp-3025	2523	8	,	,	PUNCT
fnp-3025	2523	9	microglia	microglia	ADJ
fnp-3025	2523	10	-	-	ADJ
fnp-3025	2523	11	specific	specific	ADJ
fnp-3025	2523	12	localisation	localisation	NOUN
fnp-3025	2523	13	of	of	ADP
fnp-3025	2523	14	a	a	DET
fnp-3025	2523	15	novel	novel	ADJ
fnp-3025	2523	16	calcium	calcium	NOUN
fnp-3025	2523	17	binding	bind	VERB
fnp-3025	2523	18	protein	protein	NOUN
fnp-3025	2523	19	,	,	PUNCT
fnp-3025	2523	20	iba1	iba1	PROPN
fnp-3025	2523	21	.	.	PUNCT
fnp-3025	2524	1	brain	brain	NOUN
fnp-3025	2524	2	res	re	NOUN
fnp-3025	2524	3	mol	mol	ADP
fnp-3025	2524	4	brain	brain	NOUN
fnp-3025	2524	5	res	re	NOUN
fnp-3025	2524	6	,	,	PUNCT
fnp-3025	2524	7	1998	1998	NUM
fnp-3025	2524	8	.	.	PUNCT
fnp-3025	2525	1	57(1	57(1	NUM
fnp-3025	2525	2	):	):	PUNCT
fnp-3025	2525	3	p.	p.	NOUN
fnp-3025	2525	4	1	1	NUM
fnp-3025	2525	5	-	-	SYM
fnp-3025	2525	6	9	9	NUM
fnp-3025	2525	7	.	.	X
fnp-3025	2525	8	503	503	NUM
fnp-3025	2525	9	.	.	PUNCT
fnp-3025	2526	1	lichtenberg	lichtenberg	PROPN
fnp-3025	2526	2	-	-	PUNCT
fnp-3025	2526	3	kraag	kraag	PROPN
fnp-3025	2526	4	,	,	PUNCT
fnp-3025	2526	5	b.	b.	PROPN
fnp-3025	2526	6	,	,	PUNCT
fnp-3025	2526	7	et	et	PROPN
fnp-3025	2526	8	al	al	PROPN
fnp-3025	2526	9	.	.	PROPN
fnp-3025	2526	10	,	,	PUNCT
fnp-3025	2526	11	phosphorylation	phosphorylation	NOUN
fnp-3025	2526	12	-	-	PUNCT
fnp-3025	2526	13	dependent	dependent	ADJ
fnp-3025	2526	14	epitopes	epitope	NOUN
fnp-3025	2526	15	of	of	ADP
fnp-3025	2526	16	neurofilament	neurofilament	ADJ
fnp-3025	2526	17	antibodies	antibody	NOUN
fnp-3025	2526	18	on	on	ADP
fnp-3025	2526	19	tau	tau	PROPN
fnp-3025	2526	20	protein	protein	NOUN
fnp-3025	2526	21	and	and	CCONJ
fnp-3025	2526	22	relationship	relationship	NOUN
fnp-3025	2526	23	with	with	ADP
fnp-3025	2526	24	alzheimer	alzheimer	PROPN
fnp-3025	2526	25	tau	tau	PROPN
fnp-3025	2526	26	.	.	PUNCT
fnp-3025	2527	1	proc	proc	PROPN
fnp-3025	2527	2	natl	natl	PROPN
fnp-3025	2527	3	acad	acad	PROPN
fnp-3025	2527	4	sci	sci	PROPN
fnp-3025	2527	5	u	u	PROPN
fnp-3025	2527	6	s	s	PROPN
fnp-3025	2527	7	a	a	PRON
fnp-3025	2527	8	,	,	PUNCT
fnp-3025	2527	9	1992	1992	NUM
fnp-3025	2527	10	.	.	PUNCT
fnp-3025	2528	1	89(12	89(12	NUM
fnp-3025	2528	2	):	):	PUNCT
fnp-3025	2528	3	p.	p.	NOUN
fnp-3025	2528	4	5384	5384	NUM
fnp-3025	2528	5	-	-	SYM
fnp-3025	2528	6	8	8	NUM
fnp-3025	2528	7	.	.	NUM
fnp-3025	2528	8	504	504	NUM
fnp-3025	2528	9	.	.	PUNCT
fnp-3025	2529	1	goldstein	goldstein	PROPN
fnp-3025	2529	2	,	,	PUNCT
fnp-3025	2529	3	m.e	m.e	PROPN
fnp-3025	2529	4	.	.	PROPN
fnp-3025	2529	5	,	,	PUNCT
fnp-3025	2529	6	l.a	l.a	PROPN
fnp-3025	2529	7	.	.	PROPN
fnp-3025	2529	8	sternberger	sternberger	PROPN
fnp-3025	2529	9	,	,	PUNCT
fnp-3025	2529	10	and	and	CCONJ
fnp-3025	2529	11	n.h	n.h	PROPN
fnp-3025	2529	12	.	.	PROPN
fnp-3025	2529	13	sternberger	sternberger	PROPN
fnp-3025	2529	14	,	,	PUNCT
fnp-3025	2529	15	varying	vary	VERB
fnp-3025	2529	16	degrees	degree	NOUN
fnp-3025	2529	17	of	of	ADP
fnp-3025	2529	18	phosphorylation	phosphorylation	NOUN
fnp-3025	2529	19	determine	determine	VERB
fnp-3025	2529	20	microheterogeneity	microheterogeneity	NOUN
fnp-3025	2529	21	of	of	ADP
fnp-3025	2529	22	the	the	DET
fnp-3025	2529	23	heavy	heavy	ADJ
fnp-3025	2529	24	neurofilament	neurofilament	NOUN
fnp-3025	2529	25	polypeptide	polypeptide	ADJ
fnp-3025	2529	26	(	(	PUNCT
fnp-3025	2529	27	nf	nf	NOUN
fnp-3025	2529	28	-	-	PUNCT
fnp-3025	2529	29	h	h	NOUN
fnp-3025	2529	30	)	)	PUNCT
fnp-3025	2529	31	.	.	PUNCT
fnp-3025	2530	1	j	j	PROPN
fnp-3025	2530	2	neuroimmunol	neuroimmunol	PROPN
fnp-3025	2530	3	,	,	PUNCT
fnp-3025	2530	4	1987	1987	NUM
fnp-3025	2530	5	.	.	PUNCT
fnp-3025	2531	1	14(2	14(2	NUM
fnp-3025	2531	2	):	):	PUNCT
fnp-3025	2532	1	p.	p.	NOUN
fnp-3025	2532	2	135	135	NUM
fnp-3025	2532	3	-	-	SYM
fnp-3025	2532	4	48	48	NUM
fnp-3025	2532	5	.	.	PUNCT
fnp-3025	2533	1	505	505	NUM
fnp-3025	2533	2	.	.	PUNCT
fnp-3025	2533	3	sternberger	sternberger	PROPN
fnp-3025	2533	4	,	,	PUNCT
fnp-3025	2533	5	l.a	l.a	PROPN
fnp-3025	2533	6	.	.	PROPN
fnp-3025	2533	7	and	and	CCONJ
fnp-3025	2533	8	n.h	n.h	PROPN
fnp-3025	2533	9	.	.	PROPN
fnp-3025	2533	10	sternberger	sternberger	PROPN
fnp-3025	2533	11	,	,	PUNCT
fnp-3025	2533	12	monoclonal	monoclonal	NOUN
fnp-3025	2533	13	antibodies	antibody	NOUN
fnp-3025	2533	14	distinguish	distinguish	VERB
fnp-3025	2533	15	phosphorylated	phosphorylate	VERB
fnp-3025	2533	16	and	and	CCONJ
fnp-3025	2533	17	nonphosphorylated	nonphosphorylate	VERB
fnp-3025	2533	18	forms	form	NOUN
fnp-3025	2533	19	of	of	ADP
fnp-3025	2533	20	neurofilaments	neurofilament	NOUN
fnp-3025	2533	21	in	in	ADP
fnp-3025	2533	22	situ	situ	NOUN
fnp-3025	2533	23	.	.	PUNCT
fnp-3025	2534	1	proc	proc	PROPN
fnp-3025	2534	2	natl	natl	PROPN
fnp-3025	2534	3	acad	acad	PROPN
fnp-3025	2534	4	sci	sci	PROPN
fnp-3025	2534	5	u	u	PROPN
fnp-3025	2534	6	s	s	PROPN
fnp-3025	2534	7	a	a	PRON
fnp-3025	2534	8	,	,	PUNCT
fnp-3025	2534	9	1983	1983	NUM
fnp-3025	2534	10	.	.	PUNCT
fnp-3025	2535	1	80(19	80(19	PROPN
fnp-3025	2535	2	):	):	PUNCT
fnp-3025	2535	3	p.	p.	NOUN
fnp-3025	2535	4	6126	6126	NUM
fnp-3025	2535	5	-	-	SYM
fnp-3025	2535	6	30	30	NUM
fnp-3025	2535	7	.	.	PUNCT
fnp-3025	2535	8	506	506	NUM
fnp-3025	2535	9	.	.	PUNCT
fnp-3025	2536	1	naoumenko	naoumenko	PROPN
fnp-3025	2536	2	,	,	PUNCT
fnp-3025	2536	3	j.	j.	PROPN
fnp-3025	2536	4	and	and	CCONJ
fnp-3025	2536	5	i.	i.	PROPN
fnp-3025	2536	6	feigin	feigin	PROPN
fnp-3025	2536	7	,	,	PUNCT
fnp-3025	2536	8	a	a	DET
fnp-3025	2536	9	stable	stable	ADJ
fnp-3025	2536	10	silver	silver	NOUN
fnp-3025	2536	11	solution	solution	NOUN
fnp-3025	2536	12	for	for	ADP
fnp-3025	2536	13	axon	axon	NOUN
fnp-3025	2536	14	staining	stain	VERB
fnp-3025	2536	15	in	in	ADP
fnp-3025	2536	16	paraffin	paraffin	NOUN
fnp-3025	2536	17	sections	section	NOUN
fnp-3025	2536	18	.	.	PUNCT
fnp-3025	2537	1	j	j	PROPN
fnp-3025	2537	2	neuropathol	neuropathol	PROPN
fnp-3025	2537	3	exp	exp	PROPN
fnp-3025	2537	4	neurol	neurol	PROPN
fnp-3025	2537	5	,	,	PUNCT
fnp-3025	2537	6	1967	1967	NUM
fnp-3025	2537	7	.	.	PUNCT
fnp-3025	2538	1	26(4	26(4	NUM
fnp-3025	2538	2	):	):	PUNCT
fnp-3025	2538	3	p.	p.	NOUN
fnp-3025	2538	4	669	669	NUM
fnp-3025	2538	5	-	-	SYM
fnp-3025	2538	6	673	673	NUM
fnp-3025	2538	7	.	.	PUNCT
fnp-3025	2539	1	507	507	NUM
fnp-3025	2539	2	.	.	PUNCT
fnp-3025	2540	1	campbell	campbell	PROPN
fnp-3025	2540	2	,	,	PUNCT
fnp-3025	2540	3	s.k	s.k	PROPN
fnp-3025	2540	4	.	.	PROPN
fnp-3025	2540	5	,	,	PUNCT
fnp-3025	2540	6	r.c	r.c	PROPN
fnp-3025	2540	7	.	.	PROPN
fnp-3025	2540	8	switzer	switzer	PROPN
fnp-3025	2540	9	iii	iii	PROPN
fnp-3025	2540	10	,	,	PUNCT
fnp-3025	2540	11	and	and	CCONJ
fnp-3025	2540	12	t.l	t.l	PROPN
fnp-3025	2540	13	.	.	PUNCT
fnp-3025	2540	14	martin	martin	PROPN
fnp-3025	2540	15	,	,	PUNCT
fnp-3025	2540	16	alzheimer	alzheimer	PROPN
fnp-3025	2540	17	’s	’s	PART
fnp-3025	2540	18	plaques	plaque	NOUN
fnp-3025	2540	19	and	and	CCONJ
fnp-3025	2540	20	tangles	tangle	NOUN
fnp-3025	2540	21	:	:	PUNCT
fnp-3025	2540	22	a	a	DET
fnp-3025	2540	23	controlled	control	VERB
fnp-3025	2540	24	and	and	CCONJ
fnp-3025	2540	25	enhanced	enhance	VERB
fnp-3025	2540	26	silver	silver	ADJ
fnp-3025	2540	27	staining	stain	VERB
fnp-3025	2540	28	method	method	NOUN
fnp-3025	2540	29	.	.	PUNCT
fnp-3025	2541	1	society	society	NOUN
fnp-3025	2541	2	for	for	ADP
fnp-3025	2541	3	neuroscience	neuroscience	NOUN
fnp-3025	2541	4	abstracts	abstract	NOUN
fnp-3025	2541	5	,	,	PUNCT
fnp-3025	2541	6	1987	1987	NUM
fnp-3025	2541	7	.	.	PUNCT
fnp-3025	2542	1	13	13	NUM
fnp-3025	2542	2	:	:	PUNCT
fnp-3025	2543	1	p.	p.	NOUN
fnp-3025	2543	2	687	687	NUM
fnp-3025	2543	3	.	.	PUNCT
fnp-3025	2544	1	508	508	NUM
fnp-3025	2544	2	.	.	PUNCT
fnp-3025	2545	1	cowe	cowe	NOUN
fnp-3025	2545	2	,	,	PUNCT
fnp-3025	2545	3	a.	a.	NOUN
fnp-3025	2545	4	,	,	PUNCT
fnp-3025	2545	5	der	der	ADJ
fnp-3025	2545	6	gliöse	gliöse	PRON
fnp-3025	2545	7	anteil	anteil	VERB
fnp-3025	2545	8	der	der	ADJ
fnp-3025	2545	9	senilen	senilen	ADJ
fnp-3025	2545	10	plaques	plaque	NOUN
fnp-3025	2545	11	.	.	PUNCT
fnp-3025	2546	1	zeitschrift	zeitschrift	NOUN
fnp-3025	2546	2	für	für	PROPN
fnp-3025	2546	3	die	die	VERB
fnp-3025	2546	4	gesamte	gesamte	PROPN
fnp-3025	2546	5	neurologie	neurologie	X
fnp-3025	2546	6	und	und	VERB
fnp-3025	2546	7	psychiatrie	psychiatrie	NOUN
fnp-3025	2546	8	,	,	PUNCT
fnp-3025	2546	9	1915	1915	NUM
fnp-3025	2546	10	.	.	PUNCT
fnp-3025	2547	1	29(1	29(1	NUM
fnp-3025	2547	2	):	):	PUNCT
fnp-3025	2548	1	p.	p.	NOUN
fnp-3025	2548	2	92	92	NUM
fnp-3025	2548	3	-	-	SYM
fnp-3025	2548	4	96	96	NUM
fnp-3025	2548	5	.	.	PUNCT
fnp-3025	2548	6	509	509	NUM
fnp-3025	2548	7	.	.	PUNCT
fnp-3025	2549	1	mcmenemey	mcmenemey	PROPN
fnp-3025	2549	2	,	,	PUNCT
fnp-3025	2549	3	w.h	w.h	PROPN
fnp-3025	2549	4	.	.	PROPN
fnp-3025	2549	5	,	,	PUNCT
fnp-3025	2549	6	alzheimer	alzheimer	PROPN
fnp-3025	2549	7	’s	’s	PART
fnp-3025	2549	8	disease	disease	NOUN
fnp-3025	2549	9	:	:	PUNCT
fnp-3025	2549	10	problems	problem	NOUN
fnp-3025	2549	11	concerning	concern	VERB
fnp-3025	2549	12	its	its	PRON
fnp-3025	2549	13	concept	concept	NOUN
fnp-3025	2549	14	and	and	CCONJ
fnp-3025	2549	15	nature	nature	NOUN
fnp-3025	2549	16	.	.	PUNCT
fnp-3025	2550	1	acta	acta	PROPN
fnp-3025	2550	2	neurologica	neurologica	PROPN
fnp-3025	2550	3	scandinavica	scandinavica	PROPN
fnp-3025	2550	4	,	,	PUNCT
fnp-3025	2550	5	1963	1963	NUM
fnp-3025	2550	6	.	.	PUNCT
fnp-3025	2551	1	39	39	NUM
fnp-3025	2551	2	:	:	PUNCT
fnp-3025	2552	1	p.	p.	NOUN
fnp-3025	2552	2	369	369	NUM
fnp-3025	2552	3	-	-	SYM
fnp-3025	2552	4	380	380	NUM
fnp-3025	2552	5	.	.	PUNCT
fnp-3025	2552	6	510	510	NUM
fnp-3025	2552	7	.	.	PUNCT
fnp-3025	2552	8	defelipe	defelipe	PROPN
fnp-3025	2552	9	,	,	PUNCT
fnp-3025	2552	10	j.	j.	PROPN
fnp-3025	2552	11	,	,	PUNCT
fnp-3025	2552	12	cajal	cajal	PROPN
fnp-3025	2552	13	’s	’s	PART
fnp-3025	2552	14	butterfiles	butterfile	NOUN
fnp-3025	2552	15	of	of	ADP
fnp-3025	2552	16	the	the	DET
fnp-3025	2552	17	soul	soul	NOUN
fnp-3025	2552	18	.	.	PUNCT
fnp-3025	2553	1	2010	2010	NUM
fnp-3025	2553	2	,	,	PUNCT
fnp-3025	2553	3	oxford	oxford	PROPN
fnp-3025	2553	4	university	university	PROPN
fnp-3025	2553	5	press	press	NOUN
fnp-3025	2553	6	:	:	PUNCT
fnp-3025	2553	7	new	new	PROPN
fnp-3025	2553	8	york	york	PROPN
fnp-3025	2553	9	.	.	PUNCT
fnp-3025	2554	1	511	511	NUM
fnp-3025	2554	2	.	.	PUNCT
fnp-3025	2554	3	alafuzoff	alafuzoff	PROPN
fnp-3025	2554	4	et	et	PROPN
fnp-3025	2554	5	al	al	PROPN
fnp-3025	2554	6	.	.	PROPN
fnp-3025	2554	7	,	,	PUNCT
fnp-3025	2554	8	inter	inter	ADJ
fnp-3025	2554	9	-	-	ADJ
fnp-3025	2554	10	laboratory	laboratory	ADJ
fnp-3025	2554	11	comparison	comparison	NOUN
fnp-3025	2554	12	of	of	ADP
fnp-3025	2554	13	neuropathological	neuropathological	ADJ
fnp-3025	2554	14	assessments	assessment	NOUN
fnp-3025	2554	15	of	of	ADP
fnp-3025	2554	16	beta	beta	NOUN
fnp-3025	2554	17	-	-	PUNCT
fnp-3025	2554	18	amyloid	amyloid	NOUN
fnp-3025	2554	19	protein	protein	NOUN
fnp-3025	2554	20	:	:	PUNCT
fnp-3025	2554	21	a	a	DET
fnp-3025	2554	22	study	study	NOUN
fnp-3025	2554	23	of	of	ADP
fnp-3025	2554	24	the	the	DET
fnp-3025	2554	25	brainnet	brainnet	PROPN
fnp-3025	2554	26	europe	europe	PROPN
fnp-3025	2554	27	consortium	consortium	PROPN
fnp-3025	2554	28	.	.	PUNCT
fnp-3025	2555	1	acta	acta	PROPN
fnp-3025	2555	2	neuropathologica	neuropathologica	PROPN
fnp-3025	2555	3	,	,	PUNCT
fnp-3025	2555	4	2008	2008	NUM
fnp-3025	2555	5	.	.	PUNCT
fnp-3025	2556	1	115[5	115[5	NUM
fnp-3025	2556	2	]	]	PUNCT
fnp-3025	2556	3	:	:	PUNCT
fnp-3025	2557	1	p.	p.	NOUN
fnp-3025	2557	2	533	533	NUM
fnp-3025	2557	3	-	-	SYM
fnp-3025	2557	4	546	546	NUM
fnp-3025	2557	5	512	512	NUM
fnp-3025	2557	6	.	.	PUNCT
fnp-3025	2558	1	stonebarger	stonebarger	NOUN
fnp-3025	2558	2	et	et	PROPN
fnp-3025	2558	3	al	al	PROPN
fnp-3025	2558	4	.	.	PROPN
fnp-3025	2558	5	,	,	PUNCT
fnp-3025	2558	6	amyloidosis	amyloidosis	NOUN
fnp-3025	2558	7	increase	increase	NOUN
fnp-3025	2558	8	is	be	AUX
fnp-3025	2558	9	not	not	PART
fnp-3025	2558	10	attenuated	attenuate	VERB
fnp-3025	2558	11	by	by	ADP
fnp-3025	2558	12	long	long	ADJ
fnp-3025	2558	13	-	-	PUNCT
fnp-3025	2558	14	term	term	NOUN
fnp-3025	2558	15	calorie	calorie	NOUN
fnp-3025	2558	16	restriction	restriction	NOUN
fnp-3025	2558	17	or	or	CCONJ
fnp-3025	2558	18	related	relate	VERB
fnp-3025	2558	19	to	to	PART
fnp-3025	2558	20	neuron	neuron	VERB
fnp-3025	2558	21	density	density	NOUN
fnp-3025	2558	22	in	in	ADP
fnp-3025	2558	23	the	the	DET
fnp-3025	2558	24	prefrontal	prefrontal	ADJ
fnp-3025	2558	25	cortex	cortex	NOUN
fnp-3025	2558	26	of	of	ADP
fnp-3025	2558	27	extremely	extremely	ADV
fnp-3025	2558	28	aged	aged	ADJ
fnp-3025	2558	29	rhesus	rhesus	NOUN
fnp-3025	2558	30	macaques	macaque	NOUN
fnp-3025	2558	31	.	.	PUNCT
fnp-3025	2559	1	geroscience	geroscience	NOUN
fnp-3025	2559	2	,	,	PUNCT
fnp-3025	2559	3	2020	2020	NUM
fnp-3025	2559	4	.	.	PUNCT
fnp-3025	2560	1	doi	doi	NOUN
fnp-3025	2560	2	:	:	PUNCT
fnp-3025	2560	3	10.1007	10.1007	NUM
fnp-3025	2560	4	/	/	SYM
fnp-3025	2560	5	s11357	s11357	NOUN
fnp-3025	2560	6	-	-	PUNCT
fnp-3025	2560	7	020	020	NUM
fnp-3025	2560	8	-	-	PUNCT
fnp-3025	2560	9	00259	00259	NUM
fnp-3025	2560	10	-	-	SYM
fnp-3025	2560	11	0	0	NUM
fnp-3025	2560	12	.	.	PUNCT
fnp-3025	2561	1	copyright	copyright	NOUN
fnp-3025	2561	2	:	:	PUNCT
fnp-3025	2561	3	©	©	PROPN
fnp-3025	2561	4	2020	2020	NUM
fnp-3025	2561	5	the	the	DET
fnp-3025	2561	6	author(s	author(s	NOUN
fnp-3025	2561	7	)	)	PUNCT
fnp-3025	2561	8	.	.	PUNCT
fnp-3025	2562	1	this	this	PRON
fnp-3025	2562	2	is	be	AUX
fnp-3025	2562	3	an	an	DET
fnp-3025	2562	4	open	open	ADJ
fnp-3025	2562	5	access	access	NOUN
fnp-3025	2562	6	article	article	NOUN
fnp-3025	2562	7	distributed	distribute	VERB
fnp-3025	2562	8	under	under	ADP
fnp-3025	2562	9	the	the	DET
fnp-3025	2562	10	terms	term	NOUN
fnp-3025	2562	11	of	of	ADP
fnp-3025	2562	12	the	the	DET
fnp-3025	2562	13	creative	creative	ADJ
fnp-3025	2562	14	commons	common	NOUN
fnp-3025	2562	15	attribution	attribution	NOUN
fnp-3025	2562	16	4.0	4.0	NUM
fnp-3025	2562	17	international	international	ADJ
fnp-3025	2562	18	license	license	NOUN
fnp-3025	2562	19	(	(	PUNCT
fnp-3025	2562	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3025	2562	21	)	)	PUNCT
fnp-3025	2562	22	,	,	PUNCT
fnp-3025	2562	23	which	which	PRON
fnp-3025	2562	24	permits	permit	VERB
fnp-3025	2562	25	unrestricted	unrestricted	ADJ
fnp-3025	2562	26	use	use	NOUN
fnp-3025	2562	27	,	,	PUNCT
fnp-3025	2562	28	distribution	distribution	NOUN
fnp-3025	2562	29	,	,	PUNCT
fnp-3025	2562	30	and	and	CCONJ
fnp-3025	2562	31	reproduction	reproduction	NOUN
fnp-3025	2562	32	in	in	ADP
fnp-3025	2562	33	any	any	DET
fnp-3025	2562	34	medium	medium	NOUN
fnp-3025	2562	35	,	,	PUNCT
fnp-3025	2562	36	provided	provide	VERB
fnp-3025	2562	37	the	the	DET
fnp-3025	2562	38	original	original	ADJ
fnp-3025	2562	39	author	author	NOUN
fnp-3025	2562	40	and	and	CCONJ
fnp-3025	2562	41	source	source	NOUN
fnp-3025	2562	42	are	be	AUX
fnp-3025	2562	43	credited	credit	VERB
fnp-3025	2562	44	,	,	PUNCT
fnp-3025	2562	45	a	a	DET
fnp-3025	2562	46	link	link	NOUN
fnp-3025	2562	47	to	to	ADP
fnp-3025	2562	48	the	the	DET
fnp-3025	2562	49	creative	creative	ADJ
fnp-3025	2562	50	commons	common	NOUN
fnp-3025	2562	51	license	license	NOUN
fnp-3025	2562	52	is	be	AUX
fnp-3025	2562	53	provided	provide	VERB
fnp-3025	2562	54	,	,	PUNCT
fnp-3025	2562	55	and	and	CCONJ
fnp-3025	2562	56	any	any	DET
fnp-3025	2562	57	changes	change	NOUN
fnp-3025	2562	58	are	be	AUX
fnp-3025	2562	59	indicated	indicate	VERB
fnp-3025	2562	60	.	.	PUNCT
fnp-3025	2563	1	the	the	DET
fnp-3025	2563	2	creative	creative	ADJ
fnp-3025	2563	3	commons	common	NOUN
fnp-3025	2563	4	public	public	ADJ
fnp-3025	2563	5	domain	domain	NOUN
fnp-3025	2563	6	dedication	dedication	NOUN
fnp-3025	2563	7	waiver	waiver	NOUN
fnp-3025	2563	8	(	(	PUNCT
fnp-3025	2563	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3025	2563	10	)	)	PUNCT
fnp-3025	2563	11	applies	apply	VERB
fnp-3025	2563	12	to	to	ADP
fnp-3025	2563	13	the	the	DET
fnp-3025	2563	14	data	datum	NOUN
fnp-3025	2563	15	made	make	VERB
fnp-3025	2563	16	available	available	ADJ
fnp-3025	2563	17	in	in	ADP
fnp-3025	2563	18	this	this	DET
fnp-3025	2563	19	article	article	NOUN
fnp-3025	2563	20	,	,	PUNCT
fnp-3025	2563	21	unless	unless	SCONJ
fnp-3025	2563	22	otherwise	otherwise	ADV
fnp-3025	2563	23	stated	state	VERB
fnp-3025	2563	24	.	.	PUNCT