id	sid	tid	token	lemma	pos
fnp-3050	1	1	neuropathology	neuropathology	NOUN
fnp-3050	1	2	of	of	ADP
fnp-3050	1	3	the	the	DET
fnp-3050	1	4	alzheimer	alzheimer	PROPN
fnp-3050	1	5	’s	’s	PART
fnp-3050	1	6	continuum	continuum	PROPN
fnp-3050	1	7	:	:	PUNCT
fnp-3050	1	8	an	an	DET
fnp-3050	1	9	update	update	NOUN
fnp-3050	1	10	feel	feel	VERB
fnp-3050	1	11	free	free	ADJ
fnp-3050	1	12	to	to	PART
fnp-3050	1	13	add	add	VERB
fnp-3050	1	14	comments	comment	NOUN
fnp-3050	1	15	by	by	ADP
fnp-3050	1	16	clicking	click	VERB
fnp-3050	1	17	these	these	DET
fnp-3050	1	18	icons	icon	NOUN
fnp-3050	1	19	on	on	ADP
fnp-3050	1	20	the	the	DET
fnp-3050	1	21	sidebar	sidebar	NOUN
fnp-3050	1	22	free	free	ADJ
fnp-3050	1	23	neuropathology	neuropathology	NOUN
fnp-3050	1	24	1:32	1:32	PROPN
fnp-3050	1	25	(	(	PUNCT
fnp-3050	1	26	2020	2020	NUM
fnp-3050	1	27	)	)	PUNCT
fnp-3050	1	28	review	review	VERB
fnp-3050	1	29	neuropathology	neuropathology	NOUN
fnp-3050	1	30	of	of	ADP
fnp-3050	1	31	the	the	DET
fnp-3050	1	32	alzheimer	alzheimer	PROPN
fnp-3050	1	33	’s	’s	PART
fnp-3050	1	34	continuum	continuum	PROPN
fnp-3050	1	35	:	:	PUNCT
fnp-3050	2	1	an	an	DET
fnp-3050	2	2	update	update	NOUN
fnp-3050	2	3	kurt	kurt	PROPN
fnp-3050	2	4	a.	a.	PROPN
fnp-3050	2	5	jellinger	jellinger	PROPN
fnp-3050	2	6	institute	institute	PROPN
fnp-3050	2	7	of	of	ADP
fnp-3050	2	8	clinical	clinical	ADJ
fnp-3050	2	9	neurobiology	neurobiology	NOUN
fnp-3050	2	10	,	,	PUNCT
fnp-3050	2	11	vienna	vienna	PROPN
fnp-3050	2	12	,	,	PUNCT
fnp-3050	2	13	austria	austria	PROPN
fnp-3050	2	14	address	address	NOUN
fnp-3050	2	15	for	for	ADP
fnp-3050	2	16	correspondence	correspondence	NOUN
fnp-3050	2	17	:	:	PUNCT
fnp-3050	2	18	kurt	kurt	PROPN
fnp-3050	2	19	a.	a.	PROPN
fnp-3050	2	20	jellinger	jellinger	PROPN
fnp-3050	2	21	·	·	PUNCT
fnp-3050	2	22	institute	institute	NOUN
fnp-3050	2	23	of	of	ADP
fnp-3050	2	24	clinical	clinical	ADJ
fnp-3050	2	25	neurobiology	neurobiology	NOUN
fnp-3050	2	26	·	·	PUNCT
fnp-3050	2	27	alberichgasse	alberichgasse	ADJ
fnp-3050	2	28	5/13	5/13	NUM
fnp-3050	2	29	·	·	PUNCT
fnp-3050	3	1	a-1150	a-1150	NUM
fnp-3050	3	2	vienna	vienna	PROPN
fnp-3050	3	3	·	·	PUNCT
fnp-3050	3	4	austria	austria	PROPN
fnp-3050	3	5	kurt.jellinger@univie.ac.at	kurt.jellinger@univie.ac.at	PUNCT
fnp-3050	3	6	submitted	submit	VERB
fnp-3050	3	7	:	:	PUNCT
fnp-3050	3	8	06	06	NUM
fnp-3050	3	9	october	october	PROPN
fnp-3050	3	10	2020	2020	NUM
fnp-3050	3	11	accepted	accept	VERB
fnp-3050	3	12	:	:	PUNCT
fnp-3050	3	13	07	07	NUM
fnp-3050	3	14	november	november	PROPN
fnp-3050	3	15	2020	2020	NUM
fnp-3050	3	16	copyedited	copyedit	VERB
fnp-3050	3	17	by	by	ADP
fnp-3050	3	18	:	:	PUNCT
fnp-3050	3	19	nicole	nicole	PROPN
fnp-3050	3	20	schwab	schwab	PROPN
fnp-3050	3	21	published	publish	VERB
fnp-3050	3	22	:	:	PUNCT
fnp-3050	3	23	11	11	NUM
fnp-3050	3	24	november	november	PROPN
fnp-3050	3	25	2020	2020	NUM
fnp-3050	4	1	https://doi.org/10.17879/freeneuropathology-2020-3050	https://doi.org/10.17879/freeneuropathology-2020-3050	DET
fnp-3050	4	2	keywords	keyword	NOUN
fnp-3050	4	3	:	:	PUNCT
fnp-3050	4	4	alzheimer	alzheimer	PROPN
fnp-3050	4	5	’s	’s	PART
fnp-3050	4	6	disease	disease	NOUN
fnp-3050	4	7	,	,	PUNCT
fnp-3050	4	8	β	β	NOUN
fnp-3050	4	9	-	-	NOUN
fnp-3050	4	10	amyloid	amyloid	NOUN
fnp-3050	4	11	,	,	PUNCT
fnp-3050	4	12	tau	tau	PROPN
fnp-3050	4	13	pathology	pathology	NOUN
fnp-3050	4	14	,	,	PUNCT
fnp-3050	4	15	oligomers	oligomer	NOUN
fnp-3050	4	16	,	,	PUNCT
fnp-3050	4	17	amyloid	amyloid	NOUN
fnp-3050	4	18	angiopathy	angiopathy	NOUN
fnp-3050	4	19	,	,	PUNCT
fnp-3050	4	20	alzheimer	alzheimer	PROPN
fnp-3050	4	21	subtypes	subtype	NOUN
fnp-3050	4	22	,	,	PUNCT
fnp-3050	4	23	regional	regional	ADJ
fnp-3050	4	24	vulnerabiliy	vulnerabiliy	NOUN
fnp-3050	4	25	,	,	PUNCT
fnp-3050	4	26	co	co	NOUN
fnp-3050	4	27	-	-	NOUN
fnp-3050	4	28	pathologies	pathology	NOUN
fnp-3050	4	29	abstract	abstract	ADJ
fnp-3050	4	30	alzheimer	alzheimer	PROPN
fnp-3050	4	31	’s	’s	PART
fnp-3050	4	32	disease	disease	NOUN
fnp-3050	4	33	(	(	PUNCT
fnp-3050	4	34	ad	ad	NOUN
fnp-3050	4	35	)	)	PUNCT
fnp-3050	4	36	,	,	PUNCT
fnp-3050	4	37	the	the	DET
fnp-3050	4	38	most	most	ADV
fnp-3050	4	39	common	common	ADJ
fnp-3050	4	40	form	form	NOUN
fnp-3050	4	41	of	of	ADP
fnp-3050	4	42	dementia	dementia	NOUN
fnp-3050	4	43	worldwide	worldwide	ADV
fnp-3050	4	44	,	,	PUNCT
fnp-3050	4	45	is	be	AUX
fnp-3050	4	46	a	a	DET
fnp-3050	4	47	mixed	mixed	ADJ
fnp-3050	4	48	proteinopathy	proteinopathy	ADJ
fnp-3050	4	49	(	(	PUNCT
fnp-3050	4	50	amyloid	amyloid	NOUN
fnp-3050	4	51	and	and	CCONJ
fnp-3050	4	52	tau	tau	PROPN
fnp-3050	4	53	)	)	PUNCT
fnp-3050	4	54	.	.	PUNCT
fnp-3050	5	1	originally	originally	ADV
fnp-3050	5	2	defined	define	VERB
fnp-3050	5	3	as	as	ADP
fnp-3050	5	4	a	a	DET
fnp-3050	5	5	clinicopathological	clinicopathological	ADJ
fnp-3050	5	6	entity	entity	NOUN
fnp-3050	5	7	,	,	PUNCT
fnp-3050	5	8	it	it	PRON
fnp-3050	5	9	is	be	AUX
fnp-3050	5	10	a	a	DET
fnp-3050	5	11	heterogenous	heterogenous	ADJ
fnp-3050	5	12	,	,	PUNCT
fnp-3050	5	13	multifactorial	multifactorial	ADJ
fnp-3050	5	14	disorder	disorder	NOUN
fnp-3050	5	15	,	,	PUNCT
fnp-3050	5	16	currently	currently	ADV
fnp-3050	5	17	referred	refer	VERB
fnp-3050	5	18	to	to	ADP
fnp-3050	5	19	as	as	ADP
fnp-3050	5	20	the	the	DET
fnp-3050	5	21	alzheimer	alzheimer	PROPN
fnp-3050	5	22	’s	’s	PART
fnp-3050	5	23	continuum	continuum	PROPN
fnp-3050	5	24	.	.	PUNCT
fnp-3050	6	1	its	its	PRON
fnp-3050	6	2	cardinal	cardinal	ADJ
fnp-3050	6	3	pathological	pathological	ADJ
fnp-3050	6	4	features	feature	NOUN
fnp-3050	6	5	are	be	AUX
fnp-3050	6	6	extracellular	extracellular	ADJ
fnp-3050	6	7	β	β	NOUN
fnp-3050	6	8	-	-	NOUN
fnp-3050	6	9	amyloid	amyloid	NOUN
fnp-3050	6	10	(	(	PUNCT
fnp-3050	6	11	amyloid	amyloid	NOUN
fnp-3050	6	12	plaques	plaque	NOUN
fnp-3050	6	13	)	)	PUNCT
fnp-3050	6	14	and	and	CCONJ
fnp-3050	6	15	intraneuronal	intraneuronal	ADJ
fnp-3050	6	16	tau	tau	PROPN
fnp-3050	6	17	aggregates	aggregate	NOUN
fnp-3050	6	18	forming	form	VERB
fnp-3050	6	19	neurofibrillary	neurofibrillary	ADJ
fnp-3050	6	20	tangles	tangle	NOUN
fnp-3050	6	21	,	,	PUNCT
fnp-3050	6	22	which	which	PRON
fnp-3050	6	23	are	be	AUX
fnp-3050	6	24	accompanied	accompany	VERB
fnp-3050	6	25	by	by	ADP
fnp-3050	6	26	vascular	vascular	ADJ
fnp-3050	6	27	amyloid	amyloid	NOUN
fnp-3050	6	28	deposits	deposit	NOUN
fnp-3050	6	29	(	(	PUNCT
fnp-3050	6	30	cerebral	cerebral	ADJ
fnp-3050	6	31	amyloid	amyloid	NOUN
fnp-3050	6	32	angiopathy	angiopathy	NOUN
fnp-3050	6	33	)	)	PUNCT
fnp-3050	6	34	,	,	PUNCT
fnp-3050	6	35	synapse	synapse	NOUN
fnp-3050	6	36	and	and	CCONJ
fnp-3050	6	37	neuronal	neuronal	ADJ
fnp-3050	6	38	loss	loss	NOUN
fnp-3050	6	39	,	,	PUNCT
fnp-3050	6	40	as	as	ADV
fnp-3050	6	41	well	well	ADV
fnp-3050	6	42	as	as	ADP
fnp-3050	6	43	neuroinflammation	neuroinflammation	NOUN
fnp-3050	6	44	and	and	CCONJ
fnp-3050	6	45	reactive	reactive	ADJ
fnp-3050	6	46	astrogliosis	astrogliosis	NOUN
fnp-3050	6	47	.	.	PUNCT
fnp-3050	7	1	in	in	ADP
fnp-3050	7	2	addition	addition	NOUN
fnp-3050	7	3	to	to	ADP
fnp-3050	7	4	“	"	PUNCT
fnp-3050	7	5	typical	typical	ADJ
fnp-3050	7	6	”	"	PUNCT
fnp-3050	7	7	ad	ad	NOUN
fnp-3050	7	8	,	,	PUNCT
fnp-3050	7	9	various	various	ADJ
fnp-3050	7	10	subtypes	subtype	NOUN
fnp-3050	7	11	with	with	ADP
fnp-3050	7	12	characteristic	characteristic	ADJ
fnp-3050	7	13	regional	regional	ADJ
fnp-3050	7	14	patterns	pattern	NOUN
fnp-3050	7	15	of	of	ADP
fnp-3050	7	16	tau	tau	PROPN
fnp-3050	7	17	pathology	pathology	NOUN
fnp-3050	7	18	have	have	AUX
fnp-3050	7	19	been	be	AUX
fnp-3050	7	20	described	describe	VERB
fnp-3050	7	21	that	that	SCONJ
fnp-3050	7	22	show	show	VERB
fnp-3050	7	23	distinct	distinct	ADJ
fnp-3050	7	24	clinical	clinical	ADJ
fnp-3050	7	25	features	feature	NOUN
fnp-3050	7	26	,	,	PUNCT
fnp-3050	7	27	biomarker	biomarker	NOUN
fnp-3050	7	28	levels	level	NOUN
fnp-3050	7	29	,	,	PUNCT
fnp-3050	7	30	and	and	CCONJ
fnp-3050	7	31	patterns	pattern	NOUN
fnp-3050	7	32	of	of	ADP
fnp-3050	7	33	key	key	ADJ
fnp-3050	7	34	network	network	NOUN
fnp-3050	7	35	destructions	destruction	NOUN
fnp-3050	7	36	responsible	responsible	ADJ
fnp-3050	7	37	for	for	ADP
fnp-3050	7	38	cognitive	cognitive	ADJ
fnp-3050	7	39	decline	decline	NOUN
fnp-3050	7	40	.	.	PUNCT
fnp-3050	8	1	ad	ad	NOUN
fnp-3050	8	2	is	be	AUX
fnp-3050	8	3	frequently	frequently	ADV
fnp-3050	8	4	associated	associate	VERB
fnp-3050	8	5	with	with	ADP
fnp-3050	8	6	other	other	ADJ
fnp-3050	8	7	age	age	NOUN
fnp-3050	8	8	-	-	PUNCT
fnp-3050	8	9	related	relate	VERB
fnp-3050	8	10	changes	change	NOUN
fnp-3050	8	11	including	include	VERB
fnp-3050	8	12	lewy	lewy	PROPN
fnp-3050	8	13	and	and	CCONJ
fnp-3050	8	14	tdp-43	tdp-43	PROPN
fnp-3050	8	15	pathologies	pathology	NOUN
fnp-3050	8	16	,	,	PUNCT
fnp-3050	8	17	hippocampal	hippocampal	ADJ
fnp-3050	8	18	sclerosis	sclerosis	NOUN
fnp-3050	8	19	,	,	PUNCT
fnp-3050	8	20	argyrophilic	argyrophilic	ADJ
fnp-3050	8	21	grain	grain	NOUN
fnp-3050	8	22	disease	disease	NOUN
fnp-3050	8	23	,	,	PUNCT
fnp-3050	8	24	cerebrovascular	cerebrovascular	ADJ
fnp-3050	8	25	lesions	lesion	NOUN
fnp-3050	8	26	,	,	PUNCT
fnp-3050	8	27	and	and	CCONJ
fnp-3050	8	28	others	other	NOUN
fnp-3050	8	29	.	.	PUNCT
fnp-3050	9	1	these	these	DET
fnp-3050	9	2	additional	additional	ADJ
fnp-3050	9	3	pathologies	pathology	NOUN
fnp-3050	9	4	influence	influence	VERB
fnp-3050	9	5	the	the	DET
fnp-3050	9	6	clinical	clinical	ADJ
fnp-3050	9	7	picture	picture	NOUN
fnp-3050	9	8	of	of	ADP
fnp-3050	9	9	ad	ad	NOUN
fnp-3050	9	10	,	,	PUNCT
fnp-3050	9	11	may	may	AUX
fnp-3050	9	12	accelerate	accelerate	VERB
fnp-3050	9	13	disease	disease	NOUN
fnp-3050	9	14	progression	progression	NOUN
fnp-3050	9	15	,	,	PUNCT
fnp-3050	9	16	and	and	CCONJ
fnp-3050	9	17	can	can	AUX
fnp-3050	9	18	cause	cause	VERB
fnp-3050	9	19	a	a	DET
fnp-3050	9	20	number	number	NOUN
fnp-3050	9	21	of	of	ADP
fnp-3050	9	22	challenges	challenge	NOUN
fnp-3050	9	23	in	in	ADP
fnp-3050	9	24	our	our	PRON
fnp-3050	9	25	understanding	understanding	NOUN
fnp-3050	9	26	of	of	ADP
fnp-3050	9	27	the	the	DET
fnp-3050	9	28	disease	disease	NOUN
fnp-3050	9	29	including	include	VERB
fnp-3050	9	30	the	the	DET
fnp-3050	9	31	threshold	threshold	NOUN
fnp-3050	9	32	of	of	ADP
fnp-3050	9	33	each	each	DET
fnp-3050	9	34	individual	individual	ADJ
fnp-3050	9	35	pathology	pathology	NOUN
fnp-3050	9	36	to	to	PART
fnp-3050	9	37	cause	cause	VERB
fnp-3050	9	38	dementia	dementia	NOUN
fnp-3050	9	39	and	and	CCONJ
fnp-3050	9	40	the	the	DET
fnp-3050	9	41	possibility	possibility	NOUN
fnp-3050	9	42	of	of	ADP
fnp-3050	9	43	underlying	underlie	VERB
fnp-3050	9	44	common	common	ADJ
fnp-3050	9	45	etiologies	etiology	NOUN
fnp-3050	9	46	.	.	PUNCT
fnp-3050	10	1	this	this	DET
fnp-3050	10	2	article	article	NOUN
fnp-3050	10	3	provides	provide	VERB
fnp-3050	10	4	an	an	DET
fnp-3050	10	5	up	up	ADP
fnp-3050	10	6	-	-	PUNCT
fnp-3050	10	7	to	to	ADP
fnp-3050	10	8	-	-	PUNCT
fnp-3050	10	9	date	date	NOUN
fnp-3050	10	10	overview	overview	NOUN
fnp-3050	10	11	of	of	ADP
fnp-3050	10	12	ad	ad	NOUN
fnp-3050	10	13	neuropathology	neuropathology	NOUN
fnp-3050	10	14	,	,	PUNCT
fnp-3050	10	15	its	its	PRON
fnp-3050	10	16	heterogeneity	heterogeneity	NOUN
fnp-3050	10	17	,	,	PUNCT
fnp-3050	10	18	and	and	CCONJ
fnp-3050	10	19	additional	additional	ADJ
fnp-3050	10	20	pathologies	pathology	NOUN
fnp-3050	10	21	in	in	ADP
fnp-3050	10	22	order	order	NOUN
fnp-3050	10	23	to	to	PART
fnp-3050	10	24	explain	explain	VERB
fnp-3050	10	25	the	the	DET
fnp-3050	10	26	difficulties	difficulty	NOUN
fnp-3050	10	27	in	in	ADP
fnp-3050	10	28	the	the	DET
fnp-3050	10	29	diagnosis	diagnosis	NOUN
fnp-3050	10	30	and	and	CCONJ
fnp-3050	10	31	the	the	DET
fnp-3050	10	32	failure	failure	NOUN
fnp-3050	10	33	of	of	ADP
fnp-3050	10	34	clinical	clinical	ADJ
fnp-3050	10	35	trials	trial	NOUN
fnp-3050	10	36	in	in	ADP
fnp-3050	10	37	ad	ad	NOUN
fnp-3050	10	38	patients	patient	NOUN
fnp-3050	10	39	.	.	PUNCT
fnp-3050	11	1	abbreviations	abbreviation	NOUN
fnp-3050	11	2	ad	ad	NOUN
fnp-3050	11	3	–	–	PUNCT
fnp-3050	11	4	alzheimer	alzheimer	PROPN
fnp-3050	11	5	’s	’s	PART
fnp-3050	11	6	disease	disease	NOUN
fnp-3050	11	7	,	,	PUNCT
fnp-3050	11	8	adnc	adnc	PROPN
fnp-3050	11	9	alzheimer	alzheimer	PROPN
fnp-3050	11	10	’s	’s	PART
fnp-3050	11	11	disease	disease	NOUN
fnp-3050	11	12	neuropathological	neuropathological	ADJ
fnp-3050	11	13	changes	change	NOUN
fnp-3050	11	14	,	,	PUNCT
fnp-3050	11	15	ap	ap	PROPN
fnp-3050	11	16	amyloid	amyloid	NOUN
fnp-3050	11	17	plaque	plaque	NOUN
fnp-3050	11	18	,	,	PUNCT
fnp-3050	11	19	app	app	X
fnp-3050	11	20	amyloid	amyloid	NOUN
fnp-3050	11	21	precursor	precursor	NOUN
fnp-3050	11	22	protein	protein	NOUN
fnp-3050	11	23	,	,	PUNCT
fnp-3050	11	24	aβ	aβ	DET
fnp-3050	11	25	β	β	NOUN
fnp-3050	11	26	-	-	ADJ
fnp-3050	11	27	amyloid	amyloid	NOUN
fnp-3050	11	28	peptide	peptide	NOUN
fnp-3050	11	29	,	,	PUNCT
fnp-3050	11	30	aβo	aβo	VERB
fnp-3050	11	31	aβ	aβ	ADV
fnp-3050	11	32	oligomer	oligomer	ADJ
fnp-3050	11	33	,	,	PUNCT
fnp-3050	11	34	caa	caa	NOUN
fnp-3050	11	35	cerebral	cerebral	ADJ
fnp-3050	11	36	amyloid	amyloid	PROPN
fnp-3050	11	37	angiopathy	angiopathy	NOUN
fnp-3050	11	38	,	,	PUNCT
fnp-3050	11	39	cbs	cbs	PROPN
fnp-3050	11	40	corticobasal	corticobasal	PROPN
fnp-3050	11	41	syndrome	syndrome	PROPN
fnp-3050	11	42	,	,	PUNCT
fnp-3050	11	43	cerad	cerad	PROPN
fnp-3050	11	44	consortium	consortium	NOUN
fnp-3050	11	45	to	to	PART
fnp-3050	11	46	establish	establish	VERB
fnp-3050	11	47	a	a	DET
fnp-3050	11	48	registry	registry	NOUN
fnp-3050	11	49	for	for	ADP
fnp-3050	11	50	alzheimer	alzheimer	PROPN
fnp-3050	11	51	disease	disease	NOUN
fnp-3050	11	52	,	,	PUNCT
fnp-3050	11	53	csf	csf	ADJ
fnp-3050	11	54	cerebrospinal	cerebrospinal	ADJ
fnp-3050	11	55	fluid	fluid	NOUN
fnp-3050	11	56	,	,	PUNCT
fnp-3050	11	57	cvd	cvd	NOUN
fnp-3050	11	58	cerebrovascular	cerebrovascular	ADJ
fnp-3050	11	59	disease	disease	NOUN
fnp-3050	11	60	,	,	PUNCT
fnp-3050	11	61	dlb	dlb	NOUN
fnp-3050	11	62	dementia	dementia	NOUN
fnp-3050	11	63	with	with	ADP
fnp-3050	11	64	lewy	lewy	PROPN
fnp-3050	11	65	bodies	body	NOUN
fnp-3050	11	66	,	,	PUNCT
fnp-3050	11	67	eoad	eoad	VERB
fnp-3050	11	68	early	early	ADJ
fnp-3050	11	69	-	-	PUNCT
fnp-3050	11	70	onset	onset	NOUN
fnp-3050	11	71	ad	ad	NOUN
fnp-3050	11	72	,	,	PUNCT
fnp-3050	11	73	ftld	ftld	ADJ
fnp-3050	11	74	frontotemporal	frontotemporal	ADJ
fnp-3050	11	75	lobar	lobar	ADJ
fnp-3050	11	76	degeneration	degeneration	NOUN
fnp-3050	11	77	,	,	PUNCT
fnp-3050	11	78	ftld	ftld	ADJ
fnp-3050	11	79	-	-	PUNCT
fnp-3050	11	80	tdp	tdp	NOUN
fnp-3050	11	81	frontotemporal	frontotemporal	ADJ
fnp-3050	11	82	lobar	lobar	ADJ
fnp-3050	11	83	degeneration	degeneration	NOUN
fnp-3050	11	84	with	with	ADP
fnp-3050	11	85	tdp-43	tdp-43	PROPN
fnp-3050	11	86	,	,	PUNCT
fnp-3050	11	87	gvd	gvd	VERB
fnp-3050	11	88	granulovacuolar	granulovacuolar	ADJ
fnp-3050	11	89	degeneration	degeneration	NOUN
fnp-3050	11	90	,	,	PUNCT
fnp-3050	11	91	hcsp	hcsp	NOUN
fnp-3050	11	92	-	-	PUNCT
fnp-3050	11	93	ad	ad	NOUN
fnp-3050	11	94	hippocampal	hippocampal	NOUN
fnp-3050	11	95	sparing	spare	VERB
fnp-3050	11	96	ad	ad	NOUN
fnp-3050	11	97	,	,	PUNCT
fnp-3050	11	98	hp	hp	PROPN
fnp-3050	11	99	-	-	PUNCT
fnp-3050	11	100	tau	tau	NOUN
fnp-3050	11	101	hyperphosphorylated	hyperphosphorylate	VERB
fnp-3050	11	102	tau	tau	PROPN
fnp-3050	11	103	protein	protein	NOUN
fnp-3050	11	104	,	,	PUNCT
fnp-3050	11	105	late	late	ADJ
fnp-3050	11	106	limbic	limbic	NOUN
fnp-3050	11	107	-	-	PUNCT
fnp-3050	11	108	predominant	predominant	ADJ
fnp-3050	11	109	age	age	NOUN
fnp-3050	11	110	-	-	PUNCT
fnp-3050	11	111	related	relate	VERB
fnp-3050	11	112	tdp-43	tdp-43	NOUN
fnp-3050	11	113	encephalopathy	encephalopathy	ADJ
fnp-3050	11	114	,	,	PUNCT
fnp-3050	11	115	late	late	ADJ
fnp-3050	11	116	-	-	PUNCT
fnp-3050	11	117	nc	nc	NOUN
fnp-3050	11	118	limbic	limbic	NOUN
fnp-3050	11	119	-	-	PUNCT
fnp-3050	11	120	predominant	predominant	ADJ
fnp-3050	11	121	age	age	NOUN
fnp-3050	11	122	-	-	PUNCT
fnp-3050	11	123	related	relate	VERB
fnp-3050	11	124	tdp-43	tdp-43	NOUN
fnp-3050	11	125	encephalopathy	encephalopathy	ADJ
fnp-3050	11	126	neuropathological	neuropathological	ADJ
fnp-3050	11	127	change	change	NOUN
fnp-3050	11	128	,	,	PUNCT
fnp-3050	11	129	lc	lc	PROPN
fnp-3050	11	130	locus	locus	NOUN
fnp-3050	11	131	ceruleus	ceruleus	NOUN
fnp-3050	11	132	,	,	PUNCT
fnp-3050	11	133	load	load	VERB
fnp-3050	11	134	late	late	ADJ
fnp-3050	11	135	-	-	PUNCT
fnp-3050	11	136	onset	onset	NOUN
fnp-3050	11	137	ad	ad	NOUN
fnp-3050	11	138	,	,	PUNCT
fnp-3050	11	139	lp	lp	ADJ
fnp-3050	11	140	-	-	PUNCT
fnp-3050	11	141	ad	ad	NOUN
fnp-3050	11	142	limbic	limbic	NOUN
fnp-3050	11	143	-	-	PUNCT
fnp-3050	11	144	predominant	predominant	ADJ
fnp-3050	11	145	ad	ad	NOUN
fnp-3050	11	146	,	,	PUNCT
fnp-3050	11	147	lppa	lppa	ADJ
fnp-3050	11	148	logopenic	logopenic	ADJ
fnp-3050	11	149	primary	primary	ADJ
fnp-3050	11	150	progressive	progressive	ADJ
fnp-3050	11	151	aphasia	aphasia	NOUN
fnp-3050	11	152	,	,	PUNCT
fnp-3050	11	153	ma	ma	NOUN
fnp-3050	11	154	-	-	PUNCT
fnp-3050	11	155	ad	ad	NOUN
fnp-3050	11	156	minimal	minimal	ADJ
fnp-3050	11	157	-	-	PUNCT
fnp-3050	11	158	atrophy	atrophy	NOUN
fnp-3050	11	159	ad	ad	NOUN
fnp-3050	11	160	,	,	PUNCT
fnp-3050	11	161	mci	mci	NOUN
fnp-3050	11	162	mild	mild	ADJ
fnp-3050	11	163	cognitive	cognitive	ADJ
fnp-3050	11	164	impairment	impairment	NOUN
fnp-3050	11	165	,	,	PUNCT
fnp-3050	11	166	mtl	mtl	PROPN
fnp-3050	11	167	medial	medial	ADJ
fnp-3050	11	168	temporal	temporal	ADJ
fnp-3050	11	169	lobe	lobe	NOUN
fnp-3050	11	170	,	,	PUNCT
fnp-3050	11	171	nft	nft	PROPN
fnp-3050	11	172	neurofibrillary	neurofibrillary	PROPN
fnp-3050	11	173	tangle	tangle	PROPN
fnp-3050	11	174	,	,	PUNCT
fnp-3050	11	175	nia	nia	PROPN
fnp-3050	11	176	-	-	PUNCT
fnp-3050	11	177	aa	aa	PROPN
fnp-3050	11	178	national	national	PROPN
fnp-3050	11	179	institute	institute	PROPN
fnp-3050	11	180	of	of	ADP
fnp-3050	11	181	aging	age	VERB
fnp-3050	11	182	/	/	SYM
fnp-3050	11	183	alzheimer	alzheimer	PROPN
fnp-3050	11	184	's	's	PART
fnp-3050	11	185	association	association	NOUN
fnp-3050	11	186	,	,	PUNCT
fnp-3050	11	187	np	np	ADP
fnp-3050	11	188	neuritic	neuritic	ADJ
fnp-3050	11	189	plaque	plaque	NOUN
fnp-3050	11	190	,	,	PUNCT
fnp-3050	11	191	nt	not	PART
fnp-3050	11	192	neuropil	neuropil	NOUN
fnp-3050	11	193	thread	thread	NOUN
fnp-3050	11	194	,	,	PUNCT
fnp-3050	11	195	part	part	NOUN
fnp-3050	11	196	primary	primary	ADJ
fnp-3050	11	197	age	age	NOUN
fnp-3050	11	198	-	-	PUNCT
fnp-3050	11	199	related	relate	VERB
fnp-3050	11	200	taupathy	taupathy	ADJ
fnp-3050	11	201	,	,	PUNCT
fnp-3050	11	202	pca	pca	PROPN
fnp-3050	11	203	posterior	posterior	ADJ
fnp-3050	11	204	cortical	cortical	ADJ
fnp-3050	11	205	atrophy	atrophy	NOUN
fnp-3050	11	206	,	,	PUNCT
fnp-3050	11	207	phf	phf	NOUN
fnp-3050	11	208	paired	pair	VERB
fnp-3050	11	209	helical	helical	ADJ
fnp-3050	11	210	filament	filament	NOUN
fnp-3050	11	211	,	,	PUNCT
fnp-3050	11	212	sf	sf	PROPN
fnp-3050	11	213	straight	straight	ADJ
fnp-3050	11	214	filament	filament	NOUN
fnp-3050	11	215	,	,	PUNCT
fnp-3050	11	216	tdp-43	tdp-43	NOUN
fnp-3050	11	217	43	43	NUM
fnp-3050	11	218	-	-	PUNCT
fnp-3050	11	219	kda	kda	NOUN
fnp-3050	11	220	tar	tar	NOUN
fnp-3050	11	221	dna	dna	NOUN
fnp-3050	11	222	binding	bind	VERB
fnp-3050	11	223	protein	protein	NOUN
fnp-3050	11	224	43	43	NUM
fnp-3050	11	225	.	.	PUNCT
fnp-3050	12	1	1	1	X
fnp-3050	12	2	.	.	X
fnp-3050	12	3	introduction	introduction	PROPN
fnp-3050	12	4	alzheimer	alzheimer	PROPN
fnp-3050	12	5	’s	’s	PART
fnp-3050	12	6	disease	disease	NOUN
fnp-3050	12	7	(	(	PUNCT
fnp-3050	12	8	ad	ad	NOUN
fnp-3050	12	9	)	)	PUNCT
fnp-3050	12	10	is	be	AUX
fnp-3050	12	11	the	the	DET
fnp-3050	12	12	most	most	ADV
fnp-3050	12	13	common	common	ADJ
fnp-3050	12	14	form	form	NOUN
fnp-3050	12	15	of	of	ADP
fnp-3050	12	16	dementia	dementia	NOUN
fnp-3050	12	17	,	,	PUNCT
fnp-3050	12	18	currently	currently	ADV
fnp-3050	12	19	affecting	affect	VERB
fnp-3050	12	20	around	around	ADP
fnp-3050	12	21	50	50	NUM
fnp-3050	12	22	million	million	NUM
fnp-3050	12	23	people	people	NOUN
fnp-3050	12	24	worldwide	worldwide	ADV
fnp-3050	12	25	.	.	PUNCT
fnp-3050	13	1	it	it	PRON
fnp-3050	13	2	accounts	account	VERB
fnp-3050	13	3	for	for	ADP
fnp-3050	13	4	60	60	NUM
fnp-3050	13	5	-	-	SYM
fnp-3050	13	6	70	70	NUM
fnp-3050	13	7	%	%	NOUN
fnp-3050	13	8	of	of	ADP
fnp-3050	13	9	dementia	dementia	NOUN
fnp-3050	13	10	cases	case	NOUN
fnp-3050	13	11	in	in	ADP
fnp-3050	13	12	clinical	clinical	ADJ
fnp-3050	13	13	and	and	CCONJ
fnp-3050	13	14	autopsy	autopsy	ADJ
fnp-3050	13	15	series	series	NOUN
fnp-3050	13	16	,	,	PUNCT
fnp-3050	13	17	but	but	CCONJ
fnp-3050	13	18	it	it	PRON
fnp-3050	13	19	is	be	AUX
fnp-3050	13	20	often	often	ADV
fnp-3050	13	21	associated	associate	VERB
fnp-3050	13	22	with	with	ADP
fnp-3050	13	23	other	other	ADJ
fnp-3050	13	24	confounding	confound	VERB
fnp-3050	13	25	pathologies	pathology	NOUN
fnp-3050	13	26	in	in	ADP
fnp-3050	13	27	the	the	DET
fnp-3050	13	28	elderly	elderly	ADJ
fnp-3050	13	29	.	.	PUNCT
fnp-3050	14	1	its	its	PRON
fnp-3050	14	2	incidence	incidence	NOUN
fnp-3050	14	3	increases	increase	VERB
fnp-3050	14	4	from	from	ADP
fnp-3050	14	5	2/1.000	2/1.000	NUM
fnp-3050	14	6	at	at	ADP
fnp-3050	14	7	age	age	NOUN
fnp-3050	14	8	65	65	NUM
fnp-3050	14	9	-	-	SYM
fnp-3050	14	10	74	74	NUM
fnp-3050	14	11	years	year	NOUN
fnp-3050	14	12	to	to	ADP
fnp-3050	14	13	37/1.000	37/1.000	NUM
fnp-3050	14	14	at	at	ADP
fnp-3050	14	15	age	age	NOUN
fnp-3050	14	16	85	85	NUM
fnp-3050	14	17	+	+	CCONJ
fnp-3050	15	1	[	[	X
fnp-3050	15	2	1	1	NUM
fnp-3050	15	3	]	]	PUNCT
fnp-3050	15	4	,	,	PUNCT
fnp-3050	16	1	and	and	CCONJ
fnp-3050	16	2	doubles	double	VERB
fnp-3050	16	3	every	every	DET
fnp-3050	16	4	five	five	NUM
fnp-3050	16	5	years	year	NOUN
fnp-3050	16	6	after	after	ADP
fnp-3050	16	7	age	age	NOUN
fnp-3050	16	8	65	65	NUM
fnp-3050	16	9	,	,	PUNCT
fnp-3050	16	10	with	with	ADP
fnp-3050	16	11	peaks	peak	NOUN
fnp-3050	16	12	in	in	ADP
fnp-3050	16	13	the	the	DET
fnp-3050	16	14	tenth	tenth	ADJ
fnp-3050	16	15	decade	decade	NOUN
fnp-3050	16	16	and	and	CCONJ
fnp-3050	16	17	slight	slight	ADJ
fnp-3050	16	18	decrease	decrease	NOUN
fnp-3050	16	19	afterwards	afterwards	ADV
fnp-3050	16	20	[	[	X
fnp-3050	16	21	2	2	NUM
fnp-3050	16	22	,	,	PUNCT
fnp-3050	16	23	3	3	NUM
fnp-3050	16	24	]	]	PUNCT
fnp-3050	16	25	.	.	PUNCT
fnp-3050	17	1	the	the	DET
fnp-3050	17	2	point	point	NOUN
fnp-3050	17	3	prevalence	prevalence	NOUN
fnp-3050	17	4	of	of	ADP
fnp-3050	17	5	ad	ad	NOUN
fnp-3050	17	6	among	among	ADP
fnp-3050	17	7	individuals	individual	NOUN
fnp-3050	17	8	aged	age	VERB
fnp-3050	17	9	60	60	NUM
fnp-3050	17	10	+	+	CCONJ
fnp-3050	17	11	is	be	AUX
fnp-3050	17	12	40.2/1,000	40.2/1,000	NUM
fnp-3050	17	13	persons	person	NOUN
fnp-3050	17	14	,	,	PUNCT
fnp-3050	17	15	the	the	DET
fnp-3050	17	16	pooled	pooled	ADJ
fnp-3050	17	17	annual	annual	ADJ
fnp-3050	17	18	period	period	NOUN
fnp-3050	17	19	prevalence	prevalence	NOUN
fnp-3050	17	20	is	be	AUX
fnp-3050	17	21	30.4/1,000	30.4/1,000	NUM
fnp-3050	17	22	,	,	PUNCT
fnp-3050	17	23	and	and	CCONJ
fnp-3050	17	24	the	the	DET
fnp-3050	17	25	incidence	incidence	NOUN
fnp-3050	17	26	rate	rate	NOUN
fnp-3050	17	27	is	be	AUX
fnp-3050	17	28	15.8/1,000	15.8/1,000	NUM
fnp-3050	17	29	person	person	NOUN
fnp-3050	17	30	-	-	PUNCT
fnp-3050	17	31	years	year	NOUN
fnp-3050	17	32	[	[	X
fnp-3050	17	33	4	4	NUM
fnp-3050	17	34	]	]	PUNCT
fnp-3050	17	35	.	.	PUNCT
fnp-3050	18	1	with	with	ADP
fnp-3050	18	2	the	the	DET
fnp-3050	18	3	disproportional	disproportional	ADJ
fnp-3050	18	4	increase	increase	NOUN
fnp-3050	18	5	of	of	ADP
fnp-3050	18	6	the	the	DET
fnp-3050	18	7	elderly	elderly	ADJ
fnp-3050	18	8	population	population	NOUN
fnp-3050	18	9	,	,	PUNCT
fnp-3050	18	10	the	the	DET
fnp-3050	18	11	prevalence	prevalence	NOUN
fnp-3050	18	12	of	of	ADP
fnp-3050	18	13	ad	ad	NOUN
fnp-3050	18	14	will	will	AUX
fnp-3050	18	15	approach	approach	VERB
fnp-3050	18	16	around	around	ADV
fnp-3050	18	17	132	132	NUM
fnp-3050	18	18	million	million	NUM
fnp-3050	18	19	worldwide	worldwide	ADV
fnp-3050	18	20	and	and	CCONJ
fnp-3050	18	21	up	up	ADP
fnp-3050	18	22	to	to	PART
fnp-3050	18	23	16	16	NUM
fnp-3050	18	24	million	million	NUM
fnp-3050	18	25	cases	case	NOUN
fnp-3050	18	26	in	in	ADP
fnp-3050	18	27	the	the	DET
fnp-3050	18	28	usa	usa	NOUN
fnp-3050	18	29	by	by	ADP
fnp-3050	18	30	2050	2050	NUM
fnp-3050	18	31	[	[	X
fnp-3050	18	32	5	5	NUM
fnp-3050	18	33	,	,	PUNCT
fnp-3050	18	34	6	6	NUM
fnp-3050	18	35	]	]	PUNCT
fnp-3050	18	36	,	,	PUNCT
fnp-3050	18	37	ad	ad	NOUN
fnp-3050	18	38	has	have	AUX
fnp-3050	18	39	become	become	VERB
fnp-3050	18	40	a	a	DET
fnp-3050	18	41	tremendous	tremendous	ADJ
fnp-3050	18	42	public	public	ADJ
fnp-3050	18	43	health	health	NOUN
fnp-3050	18	44	and	and	CCONJ
fnp-3050	18	45	socio	socio	NOUN
fnp-3050	18	46	-	-	PUNCT
fnp-3050	18	47	economic	economic	ADJ
fnp-3050	18	48	challenge	challenge	NOUN
fnp-3050	18	49	of	of	ADP
fnp-3050	18	50	the	the	DET
fnp-3050	18	51	21st	21st	ADJ
fnp-3050	18	52	century	century	NOUN
fnp-3050	18	53	[	[	X
fnp-3050	18	54	5	5	NUM
fnp-3050	18	55	]	]	PUNCT
fnp-3050	18	56	.	.	PUNCT
fnp-3050	19	1	as	as	SCONJ
fnp-3050	19	2	available	available	ADJ
fnp-3050	19	3	treatments	treatment	NOUN
fnp-3050	19	4	only	only	ADV
fnp-3050	19	5	target	target	VERB
fnp-3050	19	6	symptoms	symptom	NOUN
fnp-3050	19	7	and	and	CCONJ
fnp-3050	19	8	neither	neither	CCONJ
fnp-3050	19	9	slow	slow	ADJ
fnp-3050	19	10	nor	nor	CCONJ
fnp-3050	19	11	reverse	reverse	VERB
fnp-3050	19	12	the	the	DET
fnp-3050	19	13	progression	progression	NOUN
fnp-3050	19	14	of	of	ADP
fnp-3050	19	15	the	the	DET
fnp-3050	19	16	disease	disease	NOUN
fnp-3050	19	17	,	,	PUNCT
fnp-3050	19	18	the	the	DET
fnp-3050	19	19	development	development	NOUN
fnp-3050	19	20	of	of	ADP
fnp-3050	19	21	disease	disease	NOUN
fnp-3050	19	22	-	-	PUNCT
fnp-3050	19	23	modifying	modify	VERB
fnp-3050	19	24	therapeutic	therapeutic	ADJ
fnp-3050	19	25	procedures	procedure	NOUN
fnp-3050	19	26	is	be	AUX
fnp-3050	19	27	urgent	urgent	ADJ
fnp-3050	19	28	[	[	X
fnp-3050	19	29	7	7	NUM
fnp-3050	19	30	]	]	PUNCT
fnp-3050	19	31	.	.	PUNCT
fnp-3050	20	1	ad	ad	NOUN
fnp-3050	20	2	was	be	AUX
fnp-3050	20	3	originally	originally	ADV
fnp-3050	20	4	defined	define	VERB
fnp-3050	20	5	as	as	ADP
fnp-3050	20	6	a	a	DET
fnp-3050	20	7	clinicopathological	clinicopathological	ADJ
fnp-3050	20	8	entity	entity	NOUN
fnp-3050	20	9	,	,	PUNCT
fnp-3050	20	10	characterized	characterize	VERB
fnp-3050	20	11	by	by	ADP
fnp-3050	20	12	progressive	progressive	ADJ
fnp-3050	20	13	memory	memory	NOUN
fnp-3050	20	14	deficit	deficit	NOUN
fnp-3050	20	15	,	,	PUNCT
fnp-3050	20	16	involvement	involvement	NOUN
fnp-3050	20	17	of	of	ADP
fnp-3050	20	18	multiple	multiple	ADJ
fnp-3050	20	19	cognitive	cognitive	ADJ
fnp-3050	20	20	domains	domain	NOUN
fnp-3050	20	21	,	,	PUNCT
fnp-3050	20	22	and	and	CCONJ
fnp-3050	20	23	a	a	DET
fnp-3050	20	24	defining	define	VERB
fnp-3050	20	25	pathological	pathological	ADJ
fnp-3050	20	26	substrate	substrate	NOUN
fnp-3050	20	27	with	with	ADP
fnp-3050	20	28	deposition	deposition	NOUN
fnp-3050	20	29	of	of	ADP
fnp-3050	20	30	amyloid	amyloid	NOUN
fnp-3050	20	31	-	-	PUNCT
fnp-3050	20	32	β	β	X
fnp-3050	20	33	peptide	peptide	NOUN
fnp-3050	20	34	(	(	PUNCT
fnp-3050	20	35	aβ	aβ	NOUN
fnp-3050	20	36	)	)	PUNCT
fnp-3050	20	37	in	in	ADP
fnp-3050	20	38	extracellular	extracellular	ADJ
fnp-3050	20	39	plaques	plaque	NOUN
fnp-3050	20	40	and	and	CCONJ
fnp-3050	20	41	cerebral	cerebral	ADJ
fnp-3050	20	42	vasculature	vasculature	NOUN
fnp-3050	20	43	(	(	PUNCT
fnp-3050	20	44	cerebral	cerebral	ADJ
fnp-3050	20	45	amyloid	amyloid	NOUN
fnp-3050	20	46	angiopathy	angiopathy	ADJ
fnp-3050	20	47	/	/	SYM
fnp-3050	20	48	caa	caa	NOUN
fnp-3050	20	49	)	)	PUNCT
fnp-3050	20	50	,	,	PUNCT
fnp-3050	20	51	neuritic	neuritic	ADJ
fnp-3050	20	52	plaques	plaque	NOUN
fnp-3050	20	53	defined	define	VERB
fnp-3050	20	54	by	by	ADP
fnp-3050	20	55	the	the	DET
fnp-3050	20	56	presence	presence	NOUN
fnp-3050	20	57	of	of	ADP
fnp-3050	20	58	microtubule	microtubule	NOUN
fnp-3050	20	59	-	-	PUNCT
fnp-3050	20	60	associated	associate	VERB
fnp-3050	20	61	hyperphosphorylated	hyperphosphorylate	VERB
fnp-3050	20	62	tau	tau	PROPN
fnp-3050	20	63	protein	protein	NOUN
fnp-3050	20	64	(	(	PUNCT
fnp-3050	20	65	hp	hp	PROPN
fnp-3050	20	66	-	-	NOUN
fnp-3050	20	67	tau	tau	NOUN
fnp-3050	20	68	)	)	PUNCT
fnp-3050	20	69	,	,	PUNCT
fnp-3050	20	70	intraneuronal	intraneuronal	ADJ
fnp-3050	20	71	aggregations	aggregation	NOUN
fnp-3050	20	72	of	of	ADP
fnp-3050	20	73	hp	hp	PROPN
fnp-3050	20	74	-	-	PROPN
fnp-3050	20	75	tau	tau	NOUN
fnp-3050	20	76	manifesting	manifest	VERB
fnp-3050	20	77	as	as	ADP
fnp-3050	20	78	neurofibrillary	neurofibrillary	ADJ
fnp-3050	20	79	tangles	tangle	NOUN
fnp-3050	20	80	(	(	PUNCT
fnp-3050	20	81	nfts	nft	NOUN
fnp-3050	20	82	)	)	PUNCT
fnp-3050	20	83	in	in	ADP
fnp-3050	20	84	the	the	DET
fnp-3050	20	85	cell	cell	NOUN
fnp-3050	20	86	soma	soma	NOUN
fnp-3050	20	87	,	,	PUNCT
fnp-3050	20	88	and	and	CCONJ
fnp-3050	20	89	neuropil	neuropil	NOUN
fnp-3050	20	90	threads	thread	NOUN
fnp-3050	20	91	(	(	PUNCT
fnp-3050	20	92	nts	nt	NOUN
fnp-3050	20	93	)	)	PUNCT
fnp-3050	20	94	,	,	PUNCT
fnp-3050	20	95	which	which	PRON
fnp-3050	20	96	occur	occur	VERB
fnp-3050	20	97	mainly	mainly	ADV
fnp-3050	20	98	in	in	ADP
fnp-3050	20	99	dendritic	dendritic	ADJ
fnp-3050	20	100	compartments	compartment	NOUN
fnp-3050	20	101	and	and	CCONJ
fnp-3050	20	102	,	,	PUNCT
fnp-3050	20	103	to	to	ADP
fnp-3050	20	104	a	a	DET
fnp-3050	20	105	lesser	less	ADJ
fnp-3050	20	106	degree	degree	NOUN
fnp-3050	20	107	,	,	PUNCT
fnp-3050	20	108	in	in	ADP
fnp-3050	20	109	the	the	DET
fnp-3050	20	110	axonal	axonal	ADJ
fnp-3050	20	111	domain	domain	NOUN
fnp-3050	20	112	.	.	PUNCT
fnp-3050	21	1	these	these	DET
fnp-3050	21	2	changes	change	NOUN
fnp-3050	21	3	are	be	AUX
fnp-3050	21	4	accompanied	accompany	VERB
fnp-3050	21	5	by	by	ADP
fnp-3050	21	6	early	early	ADJ
fnp-3050	21	7	synaptic	synaptic	ADJ
fnp-3050	21	8	loss	loss	NOUN
fnp-3050	21	9	[	[	X
fnp-3050	21	10	8	8	NUM
fnp-3050	21	11	]	]	PUNCT
fnp-3050	21	12	,	,	PUNCT
fnp-3050	21	13	activated	activate	VERB
fnp-3050	21	14	microglia	microglia	NOUN
fnp-3050	21	15	[	[	X
fnp-3050	21	16	9	9	NUM
fnp-3050	21	17	]	]	PUNCT
fnp-3050	21	18	,	,	PUNCT
fnp-3050	21	19	mitochondrial	mitochondrial	ADJ
fnp-3050	21	20	dysfunction	dysfunction	NOUN
fnp-3050	21	21	causing	cause	VERB
fnp-3050	21	22	energy	energy	NOUN
fnp-3050	21	23	loss	loss	NOUN
fnp-3050	21	24	[	[	X
fnp-3050	21	25	10	10	NUM
fnp-3050	21	26	]	]	PUNCT
fnp-3050	21	27	,	,	PUNCT
fnp-3050	21	28	neuroinflammation	neuroinflammation	NOUN
fnp-3050	22	1	[	[	X
fnp-3050	22	2	11	11	NUM
fnp-3050	22	3	]	]	PUNCT
fnp-3050	22	4	,	,	PUNCT
fnp-3050	22	5	neurovascular	neurovascular	ADJ
fnp-3050	22	6	dysfunction	dysfunction	NOUN
fnp-3050	22	7	[	[	X
fnp-3050	22	8	12	12	NUM
fnp-3050	22	9	]	]	PUNCT
fnp-3050	22	10	,	,	PUNCT
fnp-3050	22	11	disruption	disruption	NOUN
fnp-3050	22	12	of	of	ADP
fnp-3050	22	13	the	the	DET
fnp-3050	22	14	blood	blood	NOUN
fnp-3050	22	15	-	-	PUNCT
fnp-3050	22	16	brain	brain	NOUN
fnp-3050	22	17	barrier	barrier	NOUN
fnp-3050	22	18	[	[	X
fnp-3050	22	19	13	13	NUM
fnp-3050	22	20	]	]	PUNCT
fnp-3050	22	21	,	,	PUNCT
fnp-3050	22	22	neuronal	neuronal	ADJ
fnp-3050	22	23	loss	loss	NOUN
fnp-3050	22	24	and	and	CCONJ
fnp-3050	22	25	reactive	reactive	ADJ
fnp-3050	22	26	astrogliosis	astrogliosis	NOUN
fnp-3050	22	27	[	[	X
fnp-3050	22	28	14	14	NUM
fnp-3050	22	29	]	]	PUNCT
fnp-3050	22	30	.	.	PUNCT
fnp-3050	23	1	ad	ad	NOUN
fnp-3050	23	2	,	,	PUNCT
fnp-3050	23	3	a	a	DET
fnp-3050	23	4	mixed	mixed	ADJ
fnp-3050	23	5	proteinopathy	proteinopathy	ADJ
fnp-3050	23	6	(	(	PUNCT
fnp-3050	23	7	amyloid	amyloid	NOUN
fnp-3050	23	8	,	,	PUNCT
fnp-3050	23	9	tau	tau	PROPN
fnp-3050	23	10	,	,	PUNCT
fnp-3050	23	11	tdp-43	tdp-43	PROPN
fnp-3050	23	12	,	,	PUNCT
fnp-3050	23	13	and	and	CCONJ
fnp-3050	23	14	others	other	NOUN
fnp-3050	23	15	)	)	PUNCT
fnp-3050	23	16	,	,	PUNCT
fnp-3050	23	17	is	be	AUX
fnp-3050	23	18	a	a	DET
fnp-3050	23	19	heterogenous	heterogenous	ADJ
fnp-3050	23	20	disorder	disorder	NOUN
fnp-3050	23	21	currently	currently	ADV
fnp-3050	23	22	referred	refer	VERB
fnp-3050	23	23	to	to	ADP
fnp-3050	23	24	as	as	ADP
fnp-3050	23	25	the	the	DET
fnp-3050	23	26	alzheimer	alzheimer	PROPN
fnp-3050	23	27	’s	’s	PART
fnp-3050	23	28	continuum	continuum	NOUN
fnp-3050	23	29	[	[	X
fnp-3050	23	30	15	15	NUM
fnp-3050	23	31	]	]	PUNCT
fnp-3050	23	32	with	with	ADP
fnp-3050	23	33	several	several	ADJ
fnp-3050	23	34	pathobiological	pathobiological	ADJ
fnp-3050	23	35	subtypes	subtype	NOUN
fnp-3050	23	36	and	and	CCONJ
fnp-3050	23	37	various	various	ADJ
fnp-3050	23	38	co	co	NOUN
fnp-3050	23	39	-	-	NOUN
fnp-3050	23	40	pathologies	pathology	NOUN
fnp-3050	23	41	[	[	X
fnp-3050	23	42	16	16	NUM
fnp-3050	23	43	]	]	PUNCT
fnp-3050	23	44	.	.	PUNCT
fnp-3050	24	1	the	the	DET
fnp-3050	24	2	final	final	ADJ
fnp-3050	24	3	definite	definite	ADJ
fnp-3050	24	4	diagnosis	diagnosis	NOUN
fnp-3050	24	5	of	of	ADP
fnp-3050	24	6	ad	ad	NOUN
fnp-3050	24	7	rests	rest	VERB
fnp-3050	24	8	with	with	ADP
fnp-3050	24	9	post	post	ADJ
fnp-3050	24	10	-	-	ADJ
fnp-3050	24	11	mortem	mortem	ADJ
fnp-3050	24	12	neuropathology	neuropathology	NOUN
fnp-3050	24	13	despite	despite	SCONJ
fnp-3050	24	14	the	the	DET
fnp-3050	24	15	advent	advent	NOUN
fnp-3050	24	16	of	of	ADP
fnp-3050	24	17	more	more	ADV
fnp-3050	24	18	sensitive	sensitive	ADJ
fnp-3050	24	19	neuroimaging	neuroimaging	NOUN
fnp-3050	24	20	and	and	CCONJ
fnp-3050	24	21	the	the	DET
fnp-3050	24	22	use	use	NOUN
fnp-3050	24	23	of	of	ADP
fnp-3050	24	24	reliable	reliable	ADJ
fnp-3050	24	25	biomarkers	biomarker	NOUN
fnp-3050	24	26	[	[	X
fnp-3050	24	27	17	17	NUM
fnp-3050	24	28	]	]	PUNCT
fnp-3050	24	29	.	.	PUNCT
fnp-3050	25	1	even	even	ADV
fnp-3050	25	2	though	though	SCONJ
fnp-3050	25	3	the	the	DET
fnp-3050	25	4	classical	classical	ADJ
fnp-3050	25	5	morphological	morphological	ADJ
fnp-3050	25	6	features	feature	NOUN
fnp-3050	25	7	of	of	ADP
fnp-3050	25	8	ad	ad	NOUN
fnp-3050	25	9	have	have	AUX
fnp-3050	25	10	been	be	AUX
fnp-3050	25	11	known	know	VERB
fnp-3050	25	12	for	for	ADP
fnp-3050	25	13	many	many	ADJ
fnp-3050	25	14	years	year	NOUN
fnp-3050	25	15	,	,	PUNCT
fnp-3050	25	16	the	the	PRON
fnp-3050	25	17	recently	recently	ADV
fnp-3050	25	18	used	use	VERB
fnp-3050	25	19	more	more	ADV
fnp-3050	25	20	sensitive	sensitive	ADJ
fnp-3050	25	21	immunohistochemistry	immunohistochemistry	NOUN
fnp-3050	25	22	techniques	technique	NOUN
fnp-3050	25	23	for	for	ADP
fnp-3050	25	24	aβ	aβ	NOUN
fnp-3050	25	25	and	and	CCONJ
fnp-3050	25	26	hp	hp	PROPN
fnp-3050	25	27	-	-	PUNCT
fnp-3050	25	28	tau	tau	PROPN
fnp-3050	25	29	have	have	AUX
fnp-3050	25	30	replaced	replace	VERB
fnp-3050	25	31	silver	silver	NOUN
fnp-3050	25	32	-	-	PUNCT
fnp-3050	25	33	staining	stain	VERB
fnp-3050	25	34	techniques	technique	NOUN
fnp-3050	25	35	and	and	CCONJ
fnp-3050	25	36	have	have	AUX
fnp-3050	25	37	not	not	PART
fnp-3050	25	38	only	only	ADV
fnp-3050	25	39	forwarded	forward	VERB
fnp-3050	25	40	the	the	DET
fnp-3050	25	41	diagnosis	diagnosis	NOUN
fnp-3050	25	42	of	of	ADP
fnp-3050	25	43	ad	ad	NOUN
fnp-3050	25	44	but	but	CCONJ
fnp-3050	25	45	allowed	allow	VERB
fnp-3050	25	46	a	a	DET
fnp-3050	25	47	more	more	ADV
fnp-3050	25	48	scientific	scientific	ADJ
fnp-3050	25	49	evaluation	evaluation	NOUN
fnp-3050	25	50	of	of	ADP
fnp-3050	25	51	the	the	DET
fnp-3050	25	52	disease	disease	NOUN
fnp-3050	25	53	's	's	PART
fnp-3050	25	54	pathology	pathology	NOUN
fnp-3050	25	55	.	.	PUNCT
fnp-3050	26	1	for	for	ADP
fnp-3050	26	2	the	the	DET
fnp-3050	26	3	neuropathological	neuropathological	ADJ
fnp-3050	26	4	diagnosis	diagnosis	NOUN
fnp-3050	26	5	of	of	ADP
fnp-3050	26	6	ad	ad	NOUN
fnp-3050	26	7	,	,	PUNCT
fnp-3050	26	8	the	the	DET
fnp-3050	26	9	updated	update	VERB
fnp-3050	26	10	national	national	PROPN
fnp-3050	26	11	institute	institute	NOUN
fnp-3050	26	12	on	on	ADP
fnp-3050	26	13	aging	age	VERB
fnp-3050	26	14	/	/	SYM
fnp-3050	26	15	alzheimer	alzheimer	PROPN
fnp-3050	26	16	's	's	PART
fnp-3050	26	17	association	association	NOUN
fnp-3050	26	18	(	(	PUNCT
fnp-3050	26	19	nia	nia	PROPN
fnp-3050	26	20	/	/	SYM
fnp-3050	26	21	aa	aa	NOUN
fnp-3050	26	22	)	)	PUNCT
fnp-3050	26	23	'	'	PUNCT
fnp-3050	26	24	abc	abc	PROPN
fnp-3050	26	25	'	'	PART
fnp-3050	26	26	criteria	criterion	NOUN
fnp-3050	26	27	are	be	AUX
fnp-3050	26	28	used	use	VERB
fnp-3050	26	29	[	[	PUNCT
fnp-3050	26	30	17	17	NUM
fnp-3050	26	31	]	]	PUNCT
fnp-3050	26	32	.	.	PUNCT
fnp-3050	27	1	the	the	DET
fnp-3050	27	2	morphological	morphological	ADJ
fnp-3050	27	3	changes	change	NOUN
fnp-3050	27	4	involving	involve	VERB
fnp-3050	27	5	brain	brain	NOUN
fnp-3050	27	6	regions	region	NOUN
fnp-3050	27	7	and	and	CCONJ
fnp-3050	27	8	neuronal	neuronal	ADJ
fnp-3050	27	9	cell	cell	NOUN
fnp-3050	27	10	types	type	NOUN
fnp-3050	27	11	following	follow	VERB
fnp-3050	27	12	a	a	DET
fnp-3050	27	13	stereotypical	stereotypical	ADJ
fnp-3050	27	14	pattern	pattern	NOUN
fnp-3050	27	15	[	[	X
fnp-3050	27	16	18	18	NUM
fnp-3050	27	17	]	]	PUNCT
fnp-3050	27	18	result	result	NOUN
fnp-3050	27	19	from	from	ADP
fnp-3050	27	20	selective	selective	ADJ
fnp-3050	27	21	cellular	cellular	ADJ
fnp-3050	27	22	and	and	CCONJ
fnp-3050	27	23	regional	regional	ADJ
fnp-3050	27	24	vulnerability	vulnerability	NOUN
fnp-3050	27	25	to	to	ADP
fnp-3050	27	26	pathogenic	pathogenic	ADJ
fnp-3050	27	27	factors	factor	NOUN
fnp-3050	27	28	and	and	CCONJ
fnp-3050	27	29	their	their	PRON
fnp-3050	27	30	progression	progression	NOUN
fnp-3050	27	31	through	through	ADP
fnp-3050	27	32	functionally	functionally	ADV
fnp-3050	27	33	integrated	integrate	VERB
fnp-3050	27	34	regions	region	NOUN
fnp-3050	27	35	of	of	ADP
fnp-3050	27	36	the	the	DET
fnp-3050	27	37	brain	brain	NOUN
fnp-3050	27	38	[	[	X
fnp-3050	27	39	19	19	NUM
fnp-3050	27	40	-	-	SYM
fnp-3050	27	41	23	23	NUM
fnp-3050	27	42	]	]	PUNCT
fnp-3050	27	43	as	as	ADV
fnp-3050	27	44	well	well	ADV
fnp-3050	27	45	as	as	ADP
fnp-3050	27	46	functional	functional	ADJ
fnp-3050	27	47	networks	network	NOUN
fnp-3050	27	48	that	that	PRON
fnp-3050	27	49	result	result	VERB
fnp-3050	27	50	in	in	ADP
fnp-3050	27	51	progression	progression	NOUN
fnp-3050	27	52	of	of	ADP
fnp-3050	27	53	ad	ad	NOUN
fnp-3050	27	54	[	[	X
fnp-3050	27	55	24	24	NUM
fnp-3050	27	56	,	,	PUNCT
fnp-3050	27	57	25	25	NUM
fnp-3050	27	58	]	]	PUNCT
fnp-3050	27	59	.	.	PUNCT
fnp-3050	28	1	however	however	ADV
fnp-3050	28	2	,	,	PUNCT
fnp-3050	28	3	ad	ad	NOUN
fnp-3050	28	4	is	be	AUX
fnp-3050	28	5	a	a	DET
fnp-3050	28	6	heterogenous	heterogenous	ADJ
fnp-3050	28	7	continuum	continuum	NOUN
fnp-3050	28	8	with	with	ADP
fnp-3050	28	9	a	a	DET
fnp-3050	28	10	variety	variety	NOUN
fnp-3050	28	11	of	of	ADP
fnp-3050	28	12	clinically	clinically	ADV
fnp-3050	28	13	and	and	CCONJ
fnp-3050	28	14	morphologically	morphologically	ADV
fnp-3050	28	15	defined	define	VERB
fnp-3050	28	16	subtypes	subtype	NOUN
fnp-3050	28	17	,	,	PUNCT
fnp-3050	28	18	currently	currently	ADV
fnp-3050	28	19	referred	refer	VERB
fnp-3050	28	20	to	to	ADP
fnp-3050	28	21	as	as	ADP
fnp-3050	28	22	alzheimer	alzheimer	PROPN
fnp-3050	28	23	’s	’s	PART
fnp-3050	28	24	clinical	clinical	ADJ
fnp-3050	28	25	syndrome	syndrome	NOUN
fnp-3050	28	26	[	[	X
fnp-3050	28	27	15	15	NUM
fnp-3050	28	28	]	]	X
fnp-3050	28	29	,	,	PUNCT
fnp-3050	28	30	which	which	PRON
fnp-3050	28	31	presents	present	VERB
fnp-3050	28	32	major	major	ADJ
fnp-3050	28	33	challenges	challenge	NOUN
fnp-3050	28	34	for	for	ADP
fnp-3050	28	35	both	both	DET
fnp-3050	28	36	diagnosis	diagnosis	NOUN
fnp-3050	28	37	of	of	ADP
fnp-3050	28	38	ad	ad	NOUN
fnp-3050	28	39	,	,	PUNCT
fnp-3050	28	40	monitoring	monitoring	NOUN
fnp-3050	28	41	and	and	CCONJ
fnp-3050	28	42	targeting	targeting	NOUN
fnp-3050	28	43	of	of	ADP
fnp-3050	28	44	disease	disease	NOUN
fnp-3050	28	45	progression	progression	NOUN
fnp-3050	28	46	[	[	X
fnp-3050	28	47	26	26	NUM
fnp-3050	28	48	]	]	PUNCT
fnp-3050	28	49	.	.	PUNCT
fnp-3050	29	1	the	the	DET
fnp-3050	29	2	new	new	ADJ
fnp-3050	29	3	definition	definition	NOUN
fnp-3050	29	4	of	of	ADP
fnp-3050	29	5	ad	ad	NOUN
fnp-3050	29	6	as	as	ADP
fnp-3050	29	7	a	a	DET
fnp-3050	29	8	biologically	biologically	ADV
fnp-3050	29	9	defined	define	VERB
fnp-3050	29	10	spectrum	spectrum	NOUN
fnp-3050	29	11	,	,	PUNCT
fnp-3050	29	12	using	use	VERB
fnp-3050	29	13	the	the	DET
fnp-3050	29	14	nia	nia	PROPN
fnp-3050	29	15	/	/	SYM
fnp-3050	29	16	aa	aa	PROPN
fnp-3050	29	17	framework	framework	NOUN
fnp-3050	29	18	[	[	X
fnp-3050	29	19	15	15	NUM
fnp-3050	29	20	]	]	PUNCT
fnp-3050	29	21	,	,	PUNCT
fnp-3050	29	22	enables	enable	VERB
fnp-3050	29	23	recognition	recognition	NOUN
fnp-3050	29	24	and	and	CCONJ
fnp-3050	29	25	diagnosis	diagnosis	NOUN
fnp-3050	29	26	of	of	ADP
fnp-3050	29	27	the	the	DET
fnp-3050	29	28	various	various	ADJ
fnp-3050	29	29	subtypes	subtype	NOUN
fnp-3050	29	30	of	of	ADP
fnp-3050	29	31	ad	ad	NOUN
fnp-3050	29	32	[	[	X
fnp-3050	29	33	16	16	NUM
fnp-3050	29	34	]	]	PUNCT
fnp-3050	29	35	.	.	PUNCT
fnp-3050	30	1	research	research	NOUN
fnp-3050	30	2	consensus	consensus	NOUN
fnp-3050	30	3	guidelines	guideline	NOUN
fnp-3050	30	4	have	have	AUX
fnp-3050	30	5	been	be	AUX
fnp-3050	30	6	proposed	propose	VERB
fnp-3050	30	7	for	for	SCONJ
fnp-3050	30	8	the	the	DET
fnp-3050	30	9	intra	intra	ADJ
fnp-3050	30	10	vitam	vitam	PROPN
fnp-3050	30	11	biologically	biologically	ADV
fnp-3050	30	12	-	-	PUNCT
fnp-3050	30	13	based	base	VERB
fnp-3050	30	14	categorization	categorization	NOUN
fnp-3050	30	15	termed	term	VERB
fnp-3050	30	16	'	'	PUNCT
fnp-3050	30	17	atn	atn	PROPN
fnp-3050	30	18	'	'	PUNCT
fnp-3050	30	19	,	,	PUNCT
fnp-3050	30	20	which	which	PRON
fnp-3050	30	21	uses	use	VERB
fnp-3050	30	22	combinations	combination	NOUN
fnp-3050	30	23	of	of	ADP
fnp-3050	30	24	in	in	ADP
fnp-3050	30	25	vivo	vivo	ADJ
fnp-3050	30	26	biomarkers	biomarker	NOUN
fnp-3050	30	27	for	for	ADP
fnp-3050	30	28	aβ	aβ	NOUN
fnp-3050	30	29	deposition	deposition	NOUN
fnp-3050	30	30	(	(	PUNCT
fnp-3050	30	31	a	a	X
fnp-3050	30	32	)	)	PUNCT
fnp-3050	30	33	,	,	PUNCT
fnp-3050	30	34	tau	tau	PROPN
fnp-3050	30	35	pathology	pathology	NOUN
fnp-3050	30	36	(	(	PUNCT
fnp-3050	30	37	t	t	PROPN
fnp-3050	30	38	)	)	PUNCT
fnp-3050	30	39	,	,	PUNCT
fnp-3050	30	40	and	and	CCONJ
fnp-3050	30	41	neurodegeneration	neurodegeneration	NOUN
fnp-3050	30	42	(	(	PUNCT
fnp-3050	30	43	n	n	CCONJ
fnp-3050	30	44	)	)	PUNCT
fnp-3050	30	45	.	.	PUNCT
fnp-3050	31	1	they	they	PRON
fnp-3050	31	2	use	use	VERB
fnp-3050	31	3	cerebrospinal	cerebrospinal	ADJ
fnp-3050	31	4	fluid	fluid	NOUN
fnp-3050	31	5	(	(	PUNCT
fnp-3050	31	6	csf	csf	NOUN
fnp-3050	31	7	)	)	PUNCT
fnp-3050	31	8	or	or	CCONJ
fnp-3050	31	9	plasma	plasma	NOUN
fnp-3050	31	10	biomarkers	biomarker	NOUN
fnp-3050	31	11	,	,	PUNCT
fnp-3050	31	12	pet	pet	NOUN
fnp-3050	31	13	,	,	PUNCT
fnp-3050	31	14	and	and	CCONJ
fnp-3050	31	15	functional	functional	ADJ
fnp-3050	31	16	and	and	CCONJ
fnp-3050	31	17	structural	structural	ADJ
fnp-3050	31	18	mri	mri	NOUN
fnp-3050	31	19	.	.	PUNCT
fnp-3050	32	1	the	the	DET
fnp-3050	32	2	biomarker	biomarker	NOUN
fnp-3050	32	3	profiles	profile	NOUN
fnp-3050	32	4	and	and	CCONJ
fnp-3050	32	5	categories	category	NOUN
fnp-3050	32	6	of	of	ADP
fnp-3050	32	7	the	the	DET
fnp-3050	32	8	alzheimer	alzheimer	PROPN
fnp-3050	32	9	’s	’s	PART
fnp-3050	32	10	spectrum	spectrum	NOUN
fnp-3050	32	11	referring	refer	VERB
fnp-3050	32	12	to	to	ADP
fnp-3050	32	13	ad	ad	NOUN
fnp-3050	32	14	neuropathological	neuropathological	ADJ
fnp-3050	32	15	changes	change	NOUN
fnp-3050	32	16	(	(	PUNCT
fnp-3050	32	17	adnc	adnc	ADJ
fnp-3050	32	18	)	)	PUNCT
fnp-3050	32	19	have	have	AUX
fnp-3050	32	20	been	be	AUX
fnp-3050	32	21	summarized	summarize	VERB
fnp-3050	32	22	recently	recently	ADV
fnp-3050	32	23	[	[	X
fnp-3050	32	24	27	27	NUM
fnp-3050	32	25	]	]	SYM
fnp-3050	32	26	.	.	PUNCT
fnp-3050	33	1	2	2	X
fnp-3050	33	2	.	.	X
fnp-3050	33	3	pathology	pathology	NOUN
fnp-3050	33	4	of	of	ADP
fnp-3050	33	5	alzheimer	alzheimer	PROPN
fnp-3050	33	6	’s	’s	PART
fnp-3050	33	7	disease	disease	NOUN
fnp-3050	33	8	2.1	2.1	NUM
fnp-3050	33	9	.	.	PUNCT
fnp-3050	34	1	macroscopic	macroscopic	NOUN
fnp-3050	34	2	features	feature	VERB
fnp-3050	34	3	the	the	DET
fnp-3050	34	4	ad	ad	NOUN
fnp-3050	34	5	brain	brain	NOUN
fnp-3050	34	6	often	often	ADV
fnp-3050	34	7	has	have	AUX
fnp-3050	34	8	decreased	decrease	VERB
fnp-3050	34	9	weight	weight	NOUN
fnp-3050	34	10	and	and	CCONJ
fnp-3050	34	11	at	at	ADP
fnp-3050	34	12	least	least	ADJ
fnp-3050	34	13	moderate	moderate	ADJ
fnp-3050	34	14	cortical	cortical	ADJ
fnp-3050	34	15	atrophy	atrophy	NOUN
fnp-3050	34	16	most	most	ADV
fnp-3050	34	17	marked	mark	VERB
fnp-3050	34	18	in	in	ADP
fnp-3050	34	19	the	the	DET
fnp-3050	34	20	medial	medial	ADJ
fnp-3050	34	21	temporal	temporal	ADJ
fnp-3050	34	22	lobes	lobe	NOUN
fnp-3050	34	23	(	(	PUNCT
fnp-3050	34	24	mtls	mtls	PROPN
fnp-3050	34	25	)	)	PUNCT
fnp-3050	34	26	with	with	ADP
fnp-3050	34	27	relative	relative	ADJ
fnp-3050	34	28	sparing	spare	VERB
fnp-3050	34	29	the	the	DET
fnp-3050	34	30	primary	primary	ADJ
fnp-3050	34	31	motor	motor	NOUN
fnp-3050	34	32	,	,	PUNCT
fnp-3050	34	33	somatosensory	somatosensory	NOUN
fnp-3050	34	34	and	and	CCONJ
fnp-3050	34	35	visual	visual	ADJ
fnp-3050	34	36	cortices	cortex	NOUN
fnp-3050	34	37	and	and	CCONJ
fnp-3050	34	38	enlargement	enlargement	NOUN
fnp-3050	34	39	of	of	ADP
fnp-3050	34	40	the	the	DET
fnp-3050	34	41	lateral	lateral	ADJ
fnp-3050	34	42	ventricles	ventricle	NOUN
fnp-3050	34	43	(	(	PUNCT
fnp-3050	34	44	ex	ex	X
fnp-3050	34	45	vacuo	vacuo	X
fnp-3050	34	46	hydrocephalus	hydrocephalus	NUM
fnp-3050	34	47	)	)	PUNCT
fnp-3050	34	48	.	.	PUNCT
fnp-3050	35	1	brain	brain	NOUN
fnp-3050	35	2	atrophy	atrophy	NOUN
fnp-3050	35	3	often	often	ADV
fnp-3050	35	4	involves	involve	VERB
fnp-3050	35	5	posterior	posterior	ADJ
fnp-3050	35	6	cortical	cortical	ADJ
fnp-3050	35	7	areas	area	NOUN
fnp-3050	35	8	,	,	PUNCT
fnp-3050	35	9	most	most	ADV
fnp-3050	35	10	notable	notable	ADJ
fnp-3050	35	11	in	in	ADP
fnp-3050	35	12	precuneus	precuneus	NOUN
fnp-3050	35	13	and	and	CCONJ
fnp-3050	35	14	posterior	posterior	ADJ
fnp-3050	35	15	cingulate	cingulate	NOUN
fnp-3050	35	16	gyrus	gyrus	NOUN
fnp-3050	35	17	in	in	ADP
fnp-3050	35	18	the	the	DET
fnp-3050	35	19	preclinical	preclinical	ADJ
fnp-3050	35	20	stage	stage	NOUN
fnp-3050	35	21	of	of	ADP
fnp-3050	35	22	ad	ad	NOUN
fnp-3050	35	23	[	[	X
fnp-3050	35	24	28	28	NUM
fnp-3050	35	25	]	]	PUNCT
fnp-3050	35	26	.	.	PUNCT
fnp-3050	36	1	however	however	ADV
fnp-3050	36	2	,	,	PUNCT
fnp-3050	36	3	none	none	NOUN
fnp-3050	36	4	of	of	ADP
fnp-3050	36	5	the	the	DET
fnp-3050	36	6	macroscopic	macroscopic	ADJ
fnp-3050	36	7	features	feature	NOUN
fnp-3050	36	8	are	be	AUX
fnp-3050	36	9	specific	specific	ADJ
fnp-3050	36	10	to	to	ADP
fnp-3050	36	11	ad	ad	NOUN
fnp-3050	36	12	,	,	PUNCT
fnp-3050	36	13	and	and	CCONJ
fnp-3050	36	14	healthy	healthy	ADJ
fnp-3050	36	15	elderly	elderly	ADJ
fnp-3050	36	16	people	people	NOUN
fnp-3050	36	17	often	often	ADV
fnp-3050	36	18	show	show	VERB
fnp-3050	36	19	moderate	moderate	ADJ
fnp-3050	36	20	cortical	cortical	ADJ
fnp-3050	36	21	atrophy	atrophy	NOUN
fnp-3050	36	22	especially	especially	ADV
fnp-3050	36	23	affecting	affect	VERB
fnp-3050	36	24	the	the	DET
fnp-3050	36	25	frontal	frontal	ADJ
fnp-3050	36	26	lobes	lobe	NOUN
fnp-3050	36	27	,	,	PUNCT
fnp-3050	36	28	with	with	ADP
fnp-3050	36	29	volume	volume	NOUN
fnp-3050	36	30	loss	loss	NOUN
fnp-3050	36	31	of	of	ADP
fnp-3050	36	32	the	the	DET
fnp-3050	36	33	white	white	ADJ
fnp-3050	36	34	matter	matter	NOUN
fnp-3050	36	35	[	[	X
fnp-3050	36	36	29	29	NUM
fnp-3050	36	37	]	]	PUNCT
fnp-3050	36	38	.	.	PUNCT
fnp-3050	37	1	medial	medial	ADJ
fnp-3050	37	2	temporal	temporal	ADJ
fnp-3050	37	3	atrophy	atrophy	NOUN
fnp-3050	37	4	affecting	affect	VERB
fnp-3050	37	5	amygdala	amygdala	NOUN
fnp-3050	37	6	and	and	CCONJ
fnp-3050	37	7	hippocampus	hippocampus	NOUN
fnp-3050	37	8	with	with	ADP
fnp-3050	37	9	enlarged	enlarge	VERB
fnp-3050	37	10	temporal	temporal	ADJ
fnp-3050	37	11	horn	horn	NOUN
fnp-3050	37	12	is	be	AUX
fnp-3050	37	13	typical	typical	ADJ
fnp-3050	37	14	of	of	ADP
fnp-3050	37	15	ad	ad	NOUN
fnp-3050	37	16	(	(	PUNCT
fnp-3050	37	17	fig	fig	NOUN
fnp-3050	37	18	.	.	PUNCT
fnp-3050	38	1	1	1	NUM
fnp-3050	38	2	)	)	PUNCT
fnp-3050	38	3	.	.	PUNCT
fnp-3050	39	1	however	however	ADV
fnp-3050	39	2	,	,	PUNCT
fnp-3050	39	3	this	this	PRON
fnp-3050	39	4	is	be	AUX
fnp-3050	39	5	also	also	ADV
fnp-3050	39	6	seen	see	VERB
fnp-3050	39	7	in	in	ADP
fnp-3050	39	8	other	other	ADJ
fnp-3050	39	9	age	age	NOUN
fnp-3050	39	10	-	-	PUNCT
fnp-3050	39	11	related	relate	VERB
fnp-3050	39	12	disorders	disorder	NOUN
fnp-3050	39	13	such	such	ADJ
fnp-3050	39	14	as	as	ADP
fnp-3050	39	15	hippocampal	hippocampal	ADJ
fnp-3050	39	16	sclerosis	sclerosis	NOUN
fnp-3050	39	17	[	[	X
fnp-3050	39	18	30	30	NUM
fnp-3050	39	19	]	]	PUNCT
fnp-3050	39	20	.	.	PUNCT
fnp-3050	40	1	figure	figure	NOUN
fnp-3050	40	2	1	1	NUM
fnp-3050	40	3	.	.	PUNCT
fnp-3050	40	4	comparison	comparison	NOUN
fnp-3050	40	5	between	between	ADP
fnp-3050	40	6	formalin	formalin	NOUN
fnp-3050	40	7	-	-	PUNCT
fnp-3050	40	8	fixed	fix	VERB
fnp-3050	40	9	brain	brain	NOUN
fnp-3050	40	10	slices	slice	NOUN
fnp-3050	40	11	of	of	ADP
fnp-3050	40	12	the	the	DET
fnp-3050	40	13	left	left	ADJ
fnp-3050	40	14	hemispheres	hemisphere	NOUN
fnp-3050	40	15	(	(	PUNCT
fnp-3050	40	16	level	level	NOUN
fnp-3050	40	17	of	of	ADP
fnp-3050	40	18	posterior	posterior	ADJ
fnp-3050	40	19	hippocampus	hippocampus	NOUN
fnp-3050	40	20	)	)	PUNCT
fnp-3050	40	21	of	of	ADP
fnp-3050	40	22	an	an	DET
fnp-3050	40	23	aged	aged	ADJ
fnp-3050	40	24	nondemented	nondemented	ADJ
fnp-3050	40	25	individual	individual	NOUN
fnp-3050	40	26	(	(	PUNCT
fnp-3050	40	27	a	a	NOUN
fnp-3050	40	28	)	)	PUNCT
fnp-3050	40	29	and	and	CCONJ
fnp-3050	40	30	an	an	DET
fnp-3050	40	31	ad	ad	NOUN
fnp-3050	40	32	patient	patient	NOUN
fnp-3050	40	33	(	(	PUNCT
fnp-3050	40	34	b	b	NOUN
fnp-3050	40	35	)	)	PUNCT
fnp-3050	40	36	.	.	PUNCT
fnp-3050	41	1	note	note	VERB
fnp-3050	41	2	the	the	DET
fnp-3050	41	3	marked	mark	VERB
fnp-3050	41	4	atrophy	atrophy	NOUN
fnp-3050	41	5	(	(	PUNCT
fnp-3050	41	6	thinning	thinning	NOUN
fnp-3050	41	7	of	of	ADP
fnp-3050	41	8	the	the	DET
fnp-3050	41	9	gyri	gyri	NOUN
fnp-3050	41	10	and	and	CCONJ
fnp-3050	41	11	deepening	deepening	NOUN
fnp-3050	41	12	of	of	ADP
fnp-3050	41	13	the	the	DET
fnp-3050	41	14	sulci	sulci	NOUN
fnp-3050	41	15	)	)	PUNCT
fnp-3050	41	16	in	in	ADP
fnp-3050	41	17	b	b	NUM
fnp-3050	41	18	,	,	PUNCT
fnp-3050	41	19	in	in	ADP
fnp-3050	41	20	particular	particular	ADJ
fnp-3050	41	21	hippocampal	hippocampal	ADJ
fnp-3050	41	22	atrophy	atrophy	NOUN
fnp-3050	41	23	(	(	PUNCT
fnp-3050	41	24	arrow	arrow	NOUN
fnp-3050	41	25	in	in	ADP
fnp-3050	41	26	b	b	NOUN
fnp-3050	41	27	)	)	PUNCT
fnp-3050	41	28	with	with	ADP
fnp-3050	41	29	widening	widening	NOUN
fnp-3050	41	30	of	of	ADP
fnp-3050	41	31	the	the	DET
fnp-3050	41	32	inferior	inferior	ADJ
fnp-3050	41	33	horn	horn	NOUN
fnp-3050	41	34	of	of	ADP
fnp-3050	41	35	the	the	DET
fnp-3050	41	36	second	second	ADJ
fnp-3050	41	37	ventricle	ventricle	NOUN
fnp-3050	41	38	(	(	PUNCT
fnp-3050	41	39	asterisk	asterisk	NOUN
fnp-3050	41	40	in	in	ADP
fnp-3050	41	41	b	b	PROPN
fnp-3050	41	42	)	)	PUNCT
fnp-3050	41	43	.	.	PUNCT
fnp-3050	42	1	photographs	photograph	NOUN
fnp-3050	42	2	by	by	ADP
fnp-3050	42	3	courtesy	courtesy	NOUN
fnp-3050	42	4	of	of	ADP
fnp-3050	42	5	simon	simon	PROPN
fnp-3050	42	6	fraser	fraser	PROPN
fnp-3050	42	7	and	and	CCONJ
fnp-3050	42	8	arthur	arthur	PROPN
fnp-3050	42	9	oakley	oakley	PROPN
fnp-3050	42	10	.	.	PUNCT
fnp-3050	43	1	2.2	2.2	NUM
fnp-3050	43	2	.	.	PUNCT
fnp-3050	43	3	microscopic	microscopic	PROPN
fnp-3050	43	4	features	feature	VERB
fnp-3050	43	5	the	the	DET
fnp-3050	43	6	definite	definite	ADJ
fnp-3050	43	7	diagnosis	diagnosis	NOUN
fnp-3050	43	8	of	of	ADP
fnp-3050	43	9	ad	ad	NOUN
fnp-3050	43	10	requires	require	VERB
fnp-3050	43	11	microscopic	microscopic	ADJ
fnp-3050	43	12	examination	examination	NOUN
fnp-3050	43	13	of	of	ADP
fnp-3050	43	14	multiple	multiple	ADJ
fnp-3050	43	15	brain	brain	NOUN
fnp-3050	43	16	regions	region	NOUN
fnp-3050	43	17	with	with	ADP
fnp-3050	43	18	semiquantitative	semiquantitative	ADJ
fnp-3050	43	19	assessment	assessment	NOUN
fnp-3050	43	20	of	of	ADP
fnp-3050	43	21	the	the	DET
fnp-3050	43	22	density	density	NOUN
fnp-3050	43	23	of	of	ADP
fnp-3050	43	24	lesions	lesion	NOUN
fnp-3050	43	25	and	and	CCONJ
fnp-3050	43	26	their	their	PRON
fnp-3050	43	27	topographical	topographical	ADJ
fnp-3050	43	28	distribution	distribution	NOUN
fnp-3050	43	29	.	.	PUNCT
fnp-3050	44	1	extracellular	extracellular	ADJ
fnp-3050	44	2	amyloid	amyloid	NOUN
fnp-3050	44	3	plaques	plaque	NOUN
fnp-3050	44	4	(	(	PUNCT
fnp-3050	44	5	aps	ap	NOUN
fnp-3050	44	6	)	)	PUNCT
fnp-3050	44	7	and	and	CCONJ
fnp-3050	44	8	intracellular	intracellular	ADJ
fnp-3050	44	9	nfts	nft	NOUN
fnp-3050	44	10	that	that	PRON
fnp-3050	44	11	are	be	AUX
fnp-3050	44	12	essential	essential	ADJ
fnp-3050	44	13	for	for	ADP
fnp-3050	44	14	the	the	DET
fnp-3050	44	15	neuropathological	neuropathological	ADJ
fnp-3050	44	16	diagnosis	diagnosis	NOUN
fnp-3050	44	17	,	,	PUNCT
fnp-3050	44	18	are	be	AUX
fnp-3050	44	19	associated	associate	VERB
fnp-3050	44	20	with	with	ADP
fnp-3050	44	21	tau	tau	NOUN
fnp-3050	44	22	-	-	PUNCT
fnp-3050	44	23	positive	positive	ADJ
fnp-3050	44	24	nts	nt	NOUN
fnp-3050	44	25	,	,	PUNCT
fnp-3050	44	26	dystrophic	dystrophic	ADJ
fnp-3050	44	27	neurites	neurite	NOUN
fnp-3050	44	28	and	and	CCONJ
fnp-3050	44	29	neuritic	neuritic	ADJ
fnp-3050	44	30	plaques	plaque	NOUN
fnp-3050	44	31	(	(	PUNCT
fnp-3050	44	32	nps	nps	PROPN
fnp-3050	44	33	)	)	PUNCT
fnp-3050	44	34	,	,	PUNCT
fnp-3050	44	35	caa	caa	NOUN
fnp-3050	44	36	,	,	PUNCT
fnp-3050	44	37	reactive	reactive	ADJ
fnp-3050	44	38	astrocytes	astrocyte	NOUN
fnp-3050	44	39	and	and	CCONJ
fnp-3050	44	40	activated	activate	VERB
fnp-3050	44	41	microglia	microglia	NOUN
fnp-3050	44	42	,	,	PUNCT
fnp-3050	44	43	and	and	CCONJ
fnp-3050	44	44	neuroinflammation	neuroinflammation	NOUN
fnp-3050	44	45	are	be	AUX
fnp-3050	44	46	present	present	ADJ
fnp-3050	44	47	.	.	PUNCT
fnp-3050	45	1	these	these	DET
fnp-3050	45	2	lesions	lesion	NOUN
fnp-3050	45	3	result	result	VERB
fnp-3050	45	4	in	in	ADP
fnp-3050	45	5	loss	loss	NOUN
fnp-3050	45	6	of	of	ADP
fnp-3050	45	7	synapses	synapsis	NOUN
fnp-3050	45	8	and	and	CCONJ
fnp-3050	45	9	neurons	neuron	NOUN
fnp-3050	45	10	in	in	ADP
fnp-3050	45	11	vulnerable	vulnerable	ADJ
fnp-3050	45	12	regions	region	NOUN
fnp-3050	45	13	leading	lead	VERB
fnp-3050	45	14	to	to	ADP
fnp-3050	45	15	brain	brain	NOUN
fnp-3050	45	16	atrophy	atrophy	NOUN
fnp-3050	45	17	and	and	CCONJ
fnp-3050	45	18	the	the	DET
fnp-3050	45	19	characteristic	characteristic	ADJ
fnp-3050	45	20	clinical	clinical	ADJ
fnp-3050	45	21	picture	picture	NOUN
fnp-3050	45	22	of	of	ADP
fnp-3050	45	23	the	the	DET
fnp-3050	45	24	disease	disease	NOUN
fnp-3050	45	25	.	.	PUNCT
fnp-3050	46	1	hirano	hirano	PROPN
fnp-3050	46	2	bodies	body	NOUN
fnp-3050	46	3	,	,	PUNCT
fnp-3050	46	4	granulovacuolar	granulovacuolar	ADJ
fnp-3050	46	5	degeneration	degeneration	NOUN
fnp-3050	46	6	(	(	PUNCT
fnp-3050	46	7	gvd	gvd	PROPN
fnp-3050	46	8	)	)	PUNCT
fnp-3050	46	9	,	,	PUNCT
fnp-3050	46	10	tdp-43	tdp-43	VERB
fnp-3050	46	11	deposits	deposit	NOUN
fnp-3050	46	12	,	,	PUNCT
fnp-3050	46	13	and	and	CCONJ
fnp-3050	46	14	other	other	ADJ
fnp-3050	46	15	lesions	lesion	NOUN
fnp-3050	46	16	may	may	AUX
fnp-3050	46	17	also	also	ADV
fnp-3050	46	18	be	be	AUX
fnp-3050	46	19	present	present	ADJ
fnp-3050	47	1	[	[	X
fnp-3050	47	2	31	31	NUM
fnp-3050	47	3	,	,	PUNCT
fnp-3050	47	4	32	32	NUM
fnp-3050	47	5	]	]	PUNCT
fnp-3050	47	6	.	.	PUNCT
fnp-3050	48	1	2.3	2.3	NUM
fnp-3050	48	2	.	.	PUNCT
fnp-3050	49	1	amyloid	amyloid	NOUN
fnp-3050	49	2	deposits	deposit	NOUN
fnp-3050	49	3	aps	ap	NOUN
fnp-3050	49	4	are	be	AUX
fnp-3050	49	5	formed	form	VERB
fnp-3050	49	6	by	by	ADP
fnp-3050	49	7	the	the	DET
fnp-3050	49	8	abnormal	abnormal	ADJ
fnp-3050	49	9	extracellular	extracellular	ADJ
fnp-3050	49	10	nonvascular	nonvascular	ADJ
fnp-3050	49	11	accumulation	accumulation	NOUN
fnp-3050	49	12	and	and	CCONJ
fnp-3050	49	13	deposition	deposition	NOUN
fnp-3050	49	14	of	of	ADP
fnp-3050	49	15	aβ	aβ	DET
fnp-3050	49	16	peptides	peptide	NOUN
fnp-3050	49	17	of	of	ADP
fnp-3050	49	18	varying	vary	VERB
fnp-3050	49	19	length	length	NOUN
fnp-3050	49	20	including	include	VERB
fnp-3050	49	21	those	those	PRON
fnp-3050	49	22	with	with	ADP
fnp-3050	49	23	40	40	NUM
fnp-3050	49	24	or	or	CCONJ
fnp-3050	49	25	42	42	NUM
fnp-3050	49	26	amino	amino	ADJ
fnp-3050	49	27	acids	acid	NOUN
fnp-3050	49	28	(	(	PUNCT
fnp-3050	49	29	aβ-40	aβ-40	NOUN
fnp-3050	49	30	and	and	CCONJ
fnp-3050	49	31	aβ-42	aβ-42	NUM
fnp-3050	49	32	)	)	PUNCT
fnp-3050	49	33	,	,	PUNCT
fnp-3050	49	34	resulting	result	VERB
fnp-3050	49	35	from	from	ADP
fnp-3050	49	36	the	the	DET
fnp-3050	49	37	sequential	sequential	ADJ
fnp-3050	49	38	cleavage	cleavage	NOUN
fnp-3050	49	39	of	of	ADP
fnp-3050	49	40	the	the	DET
fnp-3050	49	41	amyloid	amyloid	NOUN
fnp-3050	49	42	precursor	precursor	NOUN
fnp-3050	49	43	protein	protein	NOUN
fnp-3050	49	44	(	(	PUNCT
fnp-3050	49	45	app	app	PROPN
fnp-3050	49	46	)	)	PUNCT
fnp-3050	49	47	by	by	ADP
fnp-3050	49	48	the	the	DET
fnp-3050	49	49	enzymes	enzyme	NOUN
fnp-3050	49	50	βand	βand	CCONJ
fnp-3050	49	51	γ	γ	NOUN
fnp-3050	49	52	-	-	NOUN
fnp-3050	49	53	secretases	secretase	NOUN
fnp-3050	49	54	[	[	X
fnp-3050	49	55	33	33	NUM
fnp-3050	49	56	]	]	PUNCT
fnp-3050	49	57	.	.	PUNCT
fnp-3050	50	1	app	app	PROPN
fnp-3050	50	2	,	,	PUNCT
fnp-3050	50	3	from	from	ADP
fnp-3050	50	4	which	which	PRON
fnp-3050	50	5	aβ	aβ	NOUN
fnp-3050	50	6	is	be	AUX
fnp-3050	50	7	cleaved	cleave	VERB
fnp-3050	50	8	by	by	ADP
fnp-3050	50	9	endoproteolytic	endoproteolytic	ADJ
fnp-3050	50	10	processing	processing	NOUN
fnp-3050	50	11	,	,	PUNCT
fnp-3050	50	12	is	be	AUX
fnp-3050	50	13	a	a	DET
fnp-3050	50	14	large	large	ADJ
fnp-3050	50	15	single	single	ADJ
fnp-3050	50	16	transmembrane	transmembrane	NOUN
fnp-3050	50	17	protein	protein	NOUN
fnp-3050	50	18	,	,	PUNCT
fnp-3050	50	19	encoded	encode	VERB
fnp-3050	50	20	by	by	ADP
fnp-3050	50	21	the	the	DET
fnp-3050	50	22	app	app	NOUN
fnp-3050	50	23	gene	gene	NOUN
fnp-3050	50	24	on	on	ADP
fnp-3050	50	25	chromosome	chromosome	NOUN
fnp-3050	50	26	21	21	NUM
fnp-3050	51	1	[	[	SYM
fnp-3050	51	2	34	34	NUM
fnp-3050	51	3	,	,	PUNCT
fnp-3050	51	4	35	35	NUM
fnp-3050	51	5	]	]	PUNCT
fnp-3050	51	6	.	.	PUNCT
fnp-3050	52	1	proteolytic	proteolytic	ADJ
fnp-3050	52	2	cleavage	cleavage	NOUN
fnp-3050	52	3	of	of	ADP
fnp-3050	52	4	app	app	NOUN
fnp-3050	52	5	develops	develop	VERB
fnp-3050	52	6	mainly	mainly	ADV
fnp-3050	52	7	via	via	ADP
fnp-3050	52	8	two	two	NUM
fnp-3050	52	9	exclusive	exclusive	ADJ
fnp-3050	52	10	pathways	pathway	NOUN
fnp-3050	52	11	,	,	PUNCT
fnp-3050	52	12	the	the	DET
fnp-3050	52	13	amyloidogenic	amyloidogenic	ADJ
fnp-3050	52	14	and	and	CCONJ
fnp-3050	52	15	the	the	DET
fnp-3050	52	16	non	non	ADJ
fnp-3050	52	17	-	-	ADJ
fnp-3050	52	18	amyloidogenic	amyloidogenic	ADJ
fnp-3050	52	19	pathway	pathway	NOUN
fnp-3050	52	20	,	,	PUNCT
fnp-3050	52	21	but	but	CCONJ
fnp-3050	52	22	other	other	ADJ
fnp-3050	52	23	alternative	alternative	ADJ
fnp-3050	52	24	pathways	pathway	NOUN
fnp-3050	52	25	(	(	PUNCT
fnp-3050	52	26	η	η	NOUN
fnp-3050	52	27	-	-	NOUN
fnp-3050	52	28	secretases	secretase	NOUN
fnp-3050	52	29	,	,	PUNCT
fnp-3050	52	30	δ	δ	PROPN
fnp-3050	52	31	-	-	PUNCT
fnp-3050	52	32	secretase	secretase	NOUN
fnp-3050	52	33	,	,	PUNCT
fnp-3050	52	34	etc	etc	X
fnp-3050	52	35	.	.	X
fnp-3050	52	36	)	)	PUNCT
fnp-3050	52	37	have	have	AUX
fnp-3050	52	38	been	be	AUX
fnp-3050	52	39	described	describe	VERB
fnp-3050	52	40	for	for	ADP
fnp-3050	52	41	the	the	DET
fnp-3050	52	42	physiological	physiological	ADJ
fnp-3050	52	43	processing	processing	NOUN
fnp-3050	52	44	of	of	ADP
fnp-3050	52	45	app	app	NOUN
fnp-3050	52	46	[	[	X
fnp-3050	52	47	36	36	NUM
fnp-3050	52	48	]	]	PUNCT
fnp-3050	52	49	.	.	PUNCT
fnp-3050	53	1	the	the	DET
fnp-3050	53	2	initial	initial	ADJ
fnp-3050	53	3	cut	cut	NOUN
fnp-3050	53	4	at	at	ADP
fnp-3050	53	5	the	the	DET
fnp-3050	53	6	β	β	NOUN
fnp-3050	53	7	-	-	NOUN
fnp-3050	53	8	site	site	NOUN
fnp-3050	53	9	of	of	ADP
fnp-3050	53	10	app	app	NOUN
fnp-3050	53	11	is	be	AUX
fnp-3050	53	12	due	due	ADJ
fnp-3050	53	13	to	to	ADP
fnp-3050	53	14	the	the	DET
fnp-3050	53	15	β	β	NOUN
fnp-3050	53	16	-	-	ADJ
fnp-3050	53	17	secretase	secretase	ADJ
fnp-3050	53	18	activity	activity	NOUN
fnp-3050	53	19	enzyme	enzyme	NOUN
fnp-3050	53	20	bace1	bace1	NOUN
fnp-3050	53	21	,	,	PUNCT
fnp-3050	53	22	a	a	DET
fnp-3050	53	23	transmembrane	transmembrane	ADJ
fnp-3050	53	24	enzyme	enzyme	NOUN
fnp-3050	53	25	with	with	ADP
fnp-3050	53	26	aspartyl	aspartyl	NOUN
fnp-3050	53	27	protease	protease	NOUN
fnp-3050	53	28	activity	activity	NOUN
fnp-3050	53	29	.	.	PUNCT
fnp-3050	54	1	clearance	clearance	NOUN
fnp-3050	54	2	by	by	ADP
fnp-3050	54	3	β	β	NOUN
fnp-3050	54	4	-	-	NOUN
fnp-3050	54	5	secretase	secretase	NOUN
fnp-3050	54	6	yields	yield	VERB
fnp-3050	54	7	a	a	DET
fnp-3050	54	8	slightly	slightly	ADV
fnp-3050	54	9	shorter	short	ADJ
fnp-3050	54	10	soluble	soluble	ADJ
fnp-3050	54	11	fragment	fragment	NOUN
fnp-3050	54	12	(	(	PUNCT
fnp-3050	54	13	sappβ	sappβ	NOUN
fnp-3050	54	14	)	)	PUNCT
fnp-3050	54	15	and	and	CCONJ
fnp-3050	54	16	a	a	DET
fnp-3050	54	17	correspondingly	correspondingly	ADV
fnp-3050	54	18	longer	long	ADJ
fnp-3050	54	19	c	c	NOUN
fnp-3050	54	20	-	-	PUNCT
fnp-3050	54	21	terminal	terminal	ADJ
fnp-3050	54	22	fragment	fragment	NOUN
fnp-3050	54	23	(	(	PUNCT
fnp-3050	54	24	ctfβ	ctfβ	NOUN
fnp-3050	54	25	)	)	PUNCT
fnp-3050	54	26	or	or	CCONJ
fnp-3050	54	27	c99	c99	X
fnp-3050	54	28	[	[	X
fnp-3050	54	29	37	37	NUM
fnp-3050	54	30	]	]	PUNCT
fnp-3050	54	31	.	.	PUNCT
fnp-3050	55	1	app	app	PROPN
fnp-3050	55	2	undergoes	undergo	VERB
fnp-3050	55	3	constitutive	constitutive	ADJ
fnp-3050	55	4	shedding	shedding	NOUN
fnp-3050	55	5	by	by	ADP
fnp-3050	55	6	a	a	DET
fnp-3050	55	7	protease	protease	NOUN
fnp-3050	55	8	activity	activity	NOUN
fnp-3050	55	9	called	call	VERB
fnp-3050	55	10	α	α	NOUN
fnp-3050	55	11	-	-	NOUN
fnp-3050	55	12	secretase	secretase	NOUN
fnp-3050	55	13	,	,	PUNCT
fnp-3050	55	14	which	which	PRON
fnp-3050	55	15	appears	appear	VERB
fnp-3050	55	16	to	to	PART
fnp-3050	55	17	be	be	AUX
fnp-3050	55	18	a	a	DET
fnp-3050	55	19	metalloprotease	metalloprotease	NOUN
fnp-3050	55	20	of	of	ADP
fnp-3050	55	21	the	the	DET
fnp-3050	55	22	adam	adam	PROPN
fnp-3050	55	23	family	family	NOUN
fnp-3050	55	24	.	.	PUNCT
fnp-3050	56	1	tace	tace	PROPN
fnp-3050	56	2	(	(	PUNCT
fnp-3050	56	3	adam17	adam17	PROPN
fnp-3050	56	4	)	)	PUNCT
fnp-3050	56	5	is	be	AUX
fnp-3050	56	6	one	one	NUM
fnp-3050	56	7	of	of	ADP
fnp-3050	56	8	the	the	DET
fnp-3050	56	9	α	α	NOUN
fnp-3050	56	10	-	-	NOUN
fnp-3050	56	11	secretase	secretase	NOUN
fnp-3050	56	12	,	,	PUNCT
fnp-3050	56	13	but	but	CCONJ
fnp-3050	56	14	adam10	adam10	NOUN
fnp-3050	56	15	is	be	AUX
fnp-3050	56	16	more	more	ADV
fnp-3050	56	17	important	important	ADJ
fnp-3050	56	18	for	for	ADP
fnp-3050	56	19	α	α	NOUN
fnp-3050	56	20	-	-	PUNCT
fnp-3050	56	21	secretase	secretase	ADJ
fnp-3050	56	22	activity	activity	NOUN
fnp-3050	56	23	and	and	CCONJ
fnp-3050	56	24	sappα	sappα	NOUN
fnp-3050	56	25	production	production	NOUN
fnp-3050	56	26	.	.	PUNCT
fnp-3050	57	1	adam10	adam10	PROPN
fnp-3050	57	2	is	be	AUX
fnp-3050	57	3	the	the	DET
fnp-3050	57	4	physiologically	physiologically	ADV
fnp-3050	57	5	relevant	relevant	ADJ
fnp-3050	57	6	constitutive	constitutive	NOUN
fnp-3050	57	7	of	of	ADP
fnp-3050	57	8	α	α	NOUN
fnp-3050	57	9	-	-	NOUN
fnp-3050	57	10	secretase	secretase	NOUN
fnp-3050	57	11	in	in	ADP
fnp-3050	57	12	primary	primary	ADJ
fnp-3050	57	13	neurons	neuron	NOUN
fnp-3050	57	14	[	[	X
fnp-3050	57	15	38	38	NUM
fnp-3050	57	16	]	]	PUNCT
fnp-3050	57	17	,	,	PUNCT
fnp-3050	57	18	as	as	SCONJ
fnp-3050	57	19	has	have	AUX
fnp-3050	57	20	been	be	AUX
fnp-3050	57	21	demonstrated	demonstrate	VERB
fnp-3050	57	22	in	in	ADP
fnp-3050	57	23	vitro	vitro	X
fnp-3050	57	24	and	and	CCONJ
fnp-3050	57	25	in	in	ADP
fnp-3050	57	26	vivo	vivo	NOUN
fnp-3050	57	27	[	[	X
fnp-3050	57	28	39	39	NUM
fnp-3050	57	29	]	]	PUNCT
fnp-3050	57	30	.	.	PUNCT
fnp-3050	58	1	cleavage	cleavage	NOUN
fnp-3050	58	2	of	of	ADP
fnp-3050	58	3	app	app	NOUN
fnp-3050	58	4	by	by	ADP
fnp-3050	58	5	α	α	NOUN
fnp-3050	58	6	-	-	PUNCT
fnp-3050	58	7	secretase	secretase	NOUN
fnp-3050	58	8	releases	release	VERB
fnp-3050	58	9	the	the	DET
fnp-3050	58	10	soluble	soluble	ADJ
fnp-3050	58	11	ectodomain	ectodomain	NOUN
fnp-3050	58	12	of	of	ADP
fnp-3050	58	13	app	app	PROPN
fnp-3050	58	14	,	,	PUNCT
fnp-3050	58	15	called	call	VERB
fnp-3050	58	16	sappα	sappα	NOUN
fnp-3050	58	17	,	,	PUNCT
fnp-3050	58	18	and	and	CCONJ
fnp-3050	58	19	a	a	DET
fnp-3050	58	20	membrane	membrane	NOUN
fnp-3050	58	21	-	-	PUNCT
fnp-3050	58	22	tethered	tethered	ADJ
fnp-3050	58	23	intracellular	intracellular	NOUN
fnp-3050	58	24	c	c	NOUN
fnp-3050	58	25	-	-	PUNCT
fnp-3050	58	26	terminal	terminal	ADJ
fnp-3050	58	27	fragment	fragment	NOUN
fnp-3050	58	28	,	,	PUNCT
fnp-3050	58	29	termed	term	VERB
fnp-3050	58	30	ctfα	ctfα	PROPN
fnp-3050	58	31	of	of	ADP
fnp-3050	58	32	c83	c83	PROPN
fnp-3050	58	33	.	.	PUNCT
fnp-3050	59	1	the	the	DET
fnp-3050	59	2	amyloidogenic	amyloidogenic	ADJ
fnp-3050	59	3	(	(	PUNCT
fnp-3050	59	4	or	or	CCONJ
fnp-3050	59	5	β	β	X
fnp-3050	59	6	)	)	PUNCT
fnp-3050	59	7	cleavage	cleavage	NOUN
fnp-3050	59	8	of	of	ADP
fnp-3050	59	9	app	app	NOUN
fnp-3050	59	10	is	be	AUX
fnp-3050	59	11	in	in	ADP
fnp-3050	59	12	direct	direct	ADJ
fnp-3050	59	13	competition	competition	NOUN
fnp-3050	59	14	with	with	ADP
fnp-3050	59	15	an	an	DET
fnp-3050	59	16	alternative	alternative	ADJ
fnp-3050	59	17	non	non	ADJ
fnp-3050	59	18	-	-	ADJ
fnp-3050	59	19	amyloidogenic	amyloidogenic	ADJ
fnp-3050	59	20	pathway	pathway	NOUN
fnp-3050	59	21	(	(	PUNCT
fnp-3050	59	22	cleavage	cleavage	NOUN
fnp-3050	59	23	by	by	ADP
fnp-3050	59	24	the	the	DET
fnp-3050	59	25	α	α	NOUN
fnp-3050	59	26	-	-	NOUN
fnp-3050	59	27	secretase	secretase	NOUN
fnp-3050	59	28	within	within	ADP
fnp-3050	59	29	the	the	DET
fnp-3050	59	30	aβ	aβ	NOUN
fnp-3050	59	31	sequence	sequence	NOUN
fnp-3050	59	32	)	)	PUNCT
fnp-3050	59	33	which	which	PRON
fnp-3050	59	34	precludes	preclude	VERB
fnp-3050	59	35	the	the	DET
fnp-3050	59	36	formation	formation	NOUN
fnp-3050	59	37	of	of	ADP
fnp-3050	59	38	amyloidogenic	amyloidogenic	ADJ
fnp-3050	59	39	peptides	peptide	NOUN
fnp-3050	59	40	and	and	CCONJ
fnp-3050	59	41	leads	lead	VERB
fnp-3050	59	42	to	to	ADP
fnp-3050	59	43	soluble	soluble	ADJ
fnp-3050	59	44	sappα	sappα	NOUN
fnp-3050	59	45	,	,	PUNCT
fnp-3050	59	46	and	and	CCONJ
fnp-3050	59	47	has	have	VERB
fnp-3050	59	48	neuroprotective	neuroprotective	ADJ
fnp-3050	59	49	properties	property	NOUN
fnp-3050	59	50	preventing	prevent	VERB
fnp-3050	59	51	aβ	aβ	DET
fnp-3050	59	52	production	production	NOUN
fnp-3050	59	53	[	[	X
fnp-3050	59	54	40	40	NUM
fnp-3050	59	55	]	]	PUNCT
fnp-3050	59	56	.	.	PUNCT
fnp-3050	60	1	however	however	ADV
fnp-3050	60	2	,	,	PUNCT
fnp-3050	60	3	aberrant	aberrant	ADJ
fnp-3050	60	4	sappα	sappα	NOUN
fnp-3050	60	5	production	production	NOUN
fnp-3050	60	6	may	may	AUX
fnp-3050	60	7	tilt	tilt	VERB
fnp-3050	60	8	the	the	DET
fnp-3050	60	9	cells	cell	NOUN
fnp-3050	60	10	toward	toward	ADP
fnp-3050	60	11	unregulated	unregulated	ADJ
fnp-3050	60	12	growth	growth	NOUN
fnp-3050	60	13	,	,	PUNCT
fnp-3050	60	14	but	but	CCONJ
fnp-3050	60	15	the	the	DET
fnp-3050	60	16	underlying	underlying	ADJ
fnp-3050	60	17	mechanisms	mechanism	NOUN
fnp-3050	60	18	are	be	AUX
fnp-3050	60	19	still	still	ADV
fnp-3050	60	20	unknown	unknown	ADJ
fnp-3050	60	21	[	[	X
fnp-3050	60	22	41	41	NUM
fnp-3050	60	23	]	]	PUNCT
fnp-3050	60	24	.	.	PUNCT
fnp-3050	61	1	lastly	lastly	ADV
fnp-3050	61	2	,	,	PUNCT
fnp-3050	61	3	γ	γ	NOUN
fnp-3050	61	4	-	-	PUNCT
fnp-3050	61	5	secretase	secretase	NOUN
fnp-3050	61	6	,	,	PUNCT
fnp-3050	61	7	a	a	DET
fnp-3050	61	8	high	high	ADJ
fnp-3050	61	9	molecular	molecular	ADJ
fnp-3050	61	10	weight	weight	NOUN
fnp-3050	61	11	complex	complex	NOUN
fnp-3050	61	12	that	that	PRON
fnp-3050	61	13	consists	consist	VERB
fnp-3050	61	14	of	of	ADP
fnp-3050	61	15	presenilin	presenilin	PROPN
fnp-3050	61	16	(	(	PUNCT
fnp-3050	61	17	ps1	ps1	PROPN
fnp-3050	61	18	,	,	PUNCT
fnp-3050	61	19	ps2	ps2	PROPN
fnp-3050	61	20	)	)	PUNCT
fnp-3050	61	21	,	,	PUNCT
fnp-3050	61	22	an	an	DET
fnp-3050	61	23	aspartyl	aspartyl	NOUN
fnp-3050	61	24	membrane	membrane	NOUN
fnp-3050	61	25	protease	protease	NOUN
fnp-3050	61	26	,	,	PUNCT
fnp-3050	61	27	aph-1	aph-1	NOUN
fnp-3050	61	28	,	,	PUNCT
fnp-3050	61	29	nicastrin	nicastrin	ADJ
fnp-3050	61	30	and	and	CCONJ
fnp-3050	61	31	presenilin	presenilin	PROPN
fnp-3050	61	32	enhancer	enhancer	NOUN
fnp-3050	61	33	(	(	PUNCT
fnp-3050	61	34	pen2	pen2	PROPN
fnp-3050	61	35	)	)	PUNCT
fnp-3050	61	36	,	,	PUNCT
fnp-3050	61	37	cleaves	cleave	VERB
fnp-3050	61	38	app	app	PROPN
fnp-3050	61	39	terminal	terminal	PROPN
fnp-3050	61	40	fragments	fragment	NOUN
fnp-3050	61	41	(	(	PUNCT
fnp-3050	61	42	ctfs	ctfs	PROPN
fnp-3050	61	43	)	)	PUNCT
fnp-3050	61	44	such	such	ADJ
fnp-3050	61	45	as	as	ADP
fnp-3050	61	46	c83	c83	ADJ
fnp-3050	61	47	and	and	CCONJ
fnp-3050	61	48	c99	c99	PROPN
fnp-3050	61	49	,	,	PUNCT
fnp-3050	61	50	releasing	release	VERB
fnp-3050	61	51	3	3	NUM
fnp-3050	61	52	or	or	CCONJ
fnp-3050	61	53	4	4	NUM
fnp-3050	61	54	amino	amino	NOUN
fnp-3050	61	55	acid	acid	NOUN
fnp-3050	61	56	peptides	peptide	NOUN
fnp-3050	61	57	from	from	ADP
fnp-3050	61	58	the	the	DET
fnp-3050	61	59	transmembrane	transmembrane	NOUN
fnp-3050	61	60	fragment	fragment	NOUN
fnp-3050	61	61	of	of	ADP
fnp-3050	61	62	app	app	PROPN
fnp-3050	61	63	.	.	PUNCT
fnp-3050	62	1	notably	notably	ADV
fnp-3050	62	2	,	,	PUNCT
fnp-3050	62	3	γ	γ	PROPN
fnp-3050	62	4	-	-	PUNCT
fnp-3050	62	5	secretase	secretase	NOUN
fnp-3050	62	6	is	be	AUX
fnp-3050	62	7	active	active	ADJ
fnp-3050	62	8	on	on	ADP
fnp-3050	62	9	app	app	NOUN
fnp-3050	62	10	only	only	ADV
fnp-3050	62	11	following	follow	VERB
fnp-3050	62	12	the	the	DET
fnp-3050	62	13	antecedent	antecedent	NOUN
fnp-3050	62	14	αor	αor	PROPN
fnp-3050	62	15	β	β	NOUN
fnp-3050	62	16	-	-	NOUN
fnp-3050	62	17	secretase	secretase	NOUN
fnp-3050	62	18	.	.	PUNCT
fnp-3050	63	1	the	the	DET
fnp-3050	63	2	products	product	NOUN
fnp-3050	63	3	of	of	ADP
fnp-3050	63	4	γ	γ	PROPN
fnp-3050	63	5	-	-	ADJ
fnp-3050	63	6	secretase	secretase	ADJ
fnp-3050	63	7	cleavage	cleavage	NOUN
fnp-3050	63	8	of	of	ADP
fnp-3050	63	9	c83	c83	NOUN
fnp-3050	63	10	are	be	AUX
fnp-3050	63	11	a	a	DET
fnp-3050	63	12	3	3	NUM
fnp-3050	63	13	-	-	PUNCT
fnp-3050	63	14	kda	kda	NOUN
fnp-3050	63	15	peptide	peptide	NOUN
fnp-3050	63	16	,	,	PUNCT
fnp-3050	63	17	termed	term	VERB
fnp-3050	63	18	p3	p3	PROPN
fnp-3050	63	19	and	and	CCONJ
fnp-3050	63	20	an	an	DET
fnp-3050	63	21	app	app	NOUN
fnp-3050	63	22	intracellular	intracellular	ADJ
fnp-3050	63	23	domain	domain	NOUN
fnp-3050	63	24	(	(	PUNCT
fnp-3050	63	25	aicd	aicd	NOUN
fnp-3050	63	26	)	)	PUNCT
fnp-3050	63	27	,	,	PUNCT
fnp-3050	63	28	while	while	SCONJ
fnp-3050	63	29	γ	γ	NOUN
fnp-3050	63	30	-	-	PUNCT
fnp-3050	63	31	secretase	secretase	ADJ
fnp-3050	63	32	cleavage	cleavage	NOUN
fnp-3050	63	33	of	of	ADP
fnp-3050	63	34	c99	c99	PROPN
fnp-3050	63	35	yields	yield	VERB
fnp-3050	63	36	the	the	DET
fnp-3050	63	37	infamous	infamous	ADJ
fnp-3050	63	38	aβ	aβ	NOUN
fnp-3050	63	39	peptide	peptide	NOUN
fnp-3050	63	40	and	and	CCONJ
fnp-3050	63	41	an	an	DET
fnp-3050	63	42	identical	identical	ADJ
fnp-3050	63	43	aicd	aicd	NOUN
fnp-3050	63	44	fragment	fragment	NOUN
fnp-3050	63	45	.	.	PUNCT
fnp-3050	64	1	besides	besides	SCONJ
fnp-3050	64	2	cleavage	cleavage	NOUN
fnp-3050	64	3	by	by	ADP
fnp-3050	64	4	α-	α-	X
fnp-3050	64	5	,	,	PUNCT
fnp-3050	64	6	β-	β-	X
fnp-3050	64	7	,	,	PUNCT
fnp-3050	64	8	and	and	CCONJ
fnp-3050	64	9	γ	γ	NOUN
fnp-3050	64	10	-	-	PUNCT
fnp-3050	64	11	secretase	secretase	NOUN
fnp-3050	64	12	,	,	PUNCT
fnp-3050	64	13	other	other	ADJ
fnp-3050	64	14	n	n	CCONJ
fnp-3050	64	15	-	-	PUNCT
fnp-3050	64	16	terminal	terminal	ADJ
fnp-3050	64	17	fragments	fragment	NOUN
fnp-3050	64	18	(	(	PUNCT
fnp-3050	64	19	ntfs	ntfs	PROPN
fnp-3050	64	20	)	)	PUNCT
fnp-3050	64	21	of	of	ADP
fnp-3050	64	22	app	app	NOUN
fnp-3050	64	23	have	have	AUX
fnp-3050	64	24	been	be	AUX
fnp-3050	64	25	identified	identify	VERB
fnp-3050	64	26	that	that	PRON
fnp-3050	64	27	are	be	AUX
fnp-3050	64	28	generated	generate	VERB
fnp-3050	64	29	by	by	ADP
fnp-3050	64	30	unknown	unknown	ADJ
fnp-3050	64	31	proteases	protease	NOUN
fnp-3050	64	32	[	[	X
fnp-3050	64	33	42	42	NUM
fnp-3050	64	34	,	,	PUNCT
fnp-3050	64	35	43	43	NUM
fnp-3050	64	36	]	]	PUNCT
fnp-3050	64	37	.	.	PUNCT
fnp-3050	65	1	mounting	mount	VERB
fnp-3050	65	2	evidence	evidence	NOUN
fnp-3050	65	3	suggests	suggest	VERB
fnp-3050	65	4	that	that	SCONJ
fnp-3050	65	5	astrocytes	astrocyte	NOUN
fnp-3050	65	6	that	that	PRON
fnp-3050	65	7	have	have	VERB
fnp-3050	65	8	increased	increase	VERB
fnp-3050	65	9	levels	level	NOUN
fnp-3050	65	10	of	of	ADP
fnp-3050	65	11	app	app	PROPN
fnp-3050	65	12	,	,	PUNCT
fnp-3050	65	13	β	β	NOUN
fnp-3050	65	14	-	-	NOUN
fnp-3050	65	15	secretase	secretase	NOUN
fnp-3050	65	16	(	(	PUNCT
fnp-3050	65	17	bace1	bace1	NOUN
fnp-3050	65	18	)	)	PUNCT
fnp-3050	65	19	,	,	PUNCT
fnp-3050	65	20	and	and	CCONJ
fnp-3050	65	21	γ	γ	X
fnp-3050	65	22	-	-	PUNCT
fnp-3050	65	23	secretase	secretase	NOUN
fnp-3050	65	24	play	play	VERB
fnp-3050	65	25	an	an	DET
fnp-3050	65	26	additional	additional	ADJ
fnp-3050	65	27	role	role	NOUN
fnp-3050	65	28	in	in	ADP
fnp-3050	65	29	ad	ad	NOUN
fnp-3050	65	30	by	by	ADP
fnp-3050	65	31	secreting	secrete	VERB
fnp-3050	65	32	significant	significant	ADJ
fnp-3050	65	33	amounts	amount	NOUN
fnp-3050	65	34	of	of	ADP
fnp-3050	65	35	aβ	aβ	NOUN
fnp-3050	65	36	and	and	CCONJ
fnp-3050	65	37	contributing	contribute	VERB
fnp-3050	65	38	to	to	ADP
fnp-3050	65	39	overall	overall	ADV
fnp-3050	65	40	aβ	aβ	NOUN
fnp-3050	65	41	burden	burden	NOUN
fnp-3050	65	42	in	in	ADP
fnp-3050	65	43	the	the	DET
fnp-3050	65	44	brain	brain	NOUN
fnp-3050	65	45	[	[	X
fnp-3050	65	46	44	44	NUM
fnp-3050	65	47	]	]	PUNCT
fnp-3050	65	48	.	.	PUNCT
fnp-3050	66	1	bace1	bace1	NOUN
fnp-3050	66	2	inhibition	inhibition	VERB
fnp-3050	66	3	more	more	ADV
fnp-3050	66	4	effectively	effectively	ADV
fnp-3050	66	5	suppresses	suppress	VERB
fnp-3050	66	6	the	the	DET
fnp-3050	66	7	initial	initial	ADJ
fnp-3050	66	8	process	process	NOUN
fnp-3050	66	9	of	of	ADP
fnp-3050	66	10	plaque	plaque	NOUN
fnp-3050	66	11	formation	formation	NOUN
fnp-3050	66	12	,	,	PUNCT
fnp-3050	66	13	rather	rather	ADV
fnp-3050	66	14	than	than	ADP
fnp-3050	66	15	the	the	DET
fnp-3050	66	16	subsequent	subsequent	ADJ
fnp-3050	66	17	phase	phase	NOUN
fnp-3050	66	18	of	of	ADP
fnp-3050	66	19	plaque	plaque	NOUN
fnp-3050	66	20	growth	growth	NOUN
fnp-3050	66	21	,	,	PUNCT
fnp-3050	66	22	which	which	PRON
fnp-3050	66	23	has	have	VERB
fnp-3050	66	24	implications	implication	NOUN
fnp-3050	66	25	for	for	ADP
fnp-3050	66	26	therapeutic	therapeutic	ADJ
fnp-3050	66	27	efficiency	efficiency	NOUN
fnp-3050	66	28	for	for	ADP
fnp-3050	66	29	the	the	DET
fnp-3050	66	30	treatment	treatment	NOUN
fnp-3050	66	31	of	of	ADP
fnp-3050	66	32	ad	ad	NOUN
fnp-3050	66	33	[	[	X
fnp-3050	66	34	45	45	NUM
fnp-3050	66	35	]	]	PUNCT
fnp-3050	66	36	.	.	PUNCT
fnp-3050	67	1	ad	ad	NOUN
fnp-3050	67	2	is	be	AUX
fnp-3050	67	3	driven	drive	VERB
fnp-3050	67	4	by	by	ADP
fnp-3050	67	5	intraneuronally	intraneuronally	ADV
fnp-3050	67	6	retained	retain	VERB
fnp-3050	67	7	aβ	aβ	ADP
fnp-3050	67	8	produced	produce	VERB
fnp-3050	67	9	by	by	ADP
fnp-3050	67	10	the	the	DET
fnp-3050	67	11	ad	ad	NOUN
fnp-3050	67	12	-	-	PUNCT
fnp-3050	67	13	specific	specific	ADJ
fnp-3050	67	14	βapp	βapp	NOUN
fnp-3050	67	15	-	-	PUNCT
fnp-3050	67	16	independent	independent	ADJ
fnp-3050	67	17	pathway	pathway	NOUN
fnp-3050	67	18	[	[	X
fnp-3050	67	19	46	46	NUM
fnp-3050	67	20	]	]	PUNCT
fnp-3050	67	21	.	.	PUNCT
fnp-3050	68	1	neuronal	neuronal	ADJ
fnp-3050	68	2	aβ-42	aβ-42	ADV
fnp-3050	68	3	is	be	AUX
fnp-3050	68	4	enriched	enrich	VERB
fnp-3050	68	5	in	in	ADP
fnp-3050	68	6	small	small	ADJ
fnp-3050	68	7	vesicles	vesicle	NOUN
fnp-3050	68	8	at	at	ADP
fnp-3050	68	9	the	the	DET
fnp-3050	68	10	presynaptic	presynaptic	ADJ
fnp-3050	68	11	side	side	NOUN
fnp-3050	68	12	of	of	ADP
fnp-3050	68	13	synapses	synapsis	NOUN
fnp-3050	68	14	[	[	X
fnp-3050	68	15	47	47	NUM
fnp-3050	68	16	]	]	PUNCT
fnp-3050	68	17	.	.	PUNCT
fnp-3050	69	1	aβ	aβ	PRON
fnp-3050	69	2	deposits	deposit	NOUN
fnp-3050	69	3	contain	contain	VERB
fnp-3050	69	4	a	a	DET
fnp-3050	69	5	mixture	mixture	NOUN
fnp-3050	69	6	of	of	ADP
fnp-3050	69	7	various	various	ADJ
fnp-3050	69	8	isoforms	isoform	NOUN
fnp-3050	69	9	.	.	PUNCT
fnp-3050	70	1	the	the	DET
fnp-3050	70	2	most	most	ADV
fnp-3050	70	3	common	common	ADJ
fnp-3050	70	4	are	be	AUX
fnp-3050	70	5	aβ-40	aβ-40	ADJ
fnp-3050	70	6	(	(	PUNCT
fnp-3050	70	7	under	under	ADP
fnp-3050	70	8	physiologic	physiologic	ADJ
fnp-3050	70	9	conditions	condition	NOUN
fnp-3050	70	10	around	around	ADP
fnp-3050	70	11	90	90	NUM
fnp-3050	70	12	%	%	NOUN
fnp-3050	70	13	)	)	PUNCT
fnp-3050	70	14	,	,	PUNCT
fnp-3050	70	15	aβ-38	aβ-38	NOUN
fnp-3050	70	16	and	and	CCONJ
fnp-3050	70	17	aβ-42	aβ-42	ADV
fnp-3050	70	18	(	(	PUNCT
fnp-3050	70	19	less	less	ADJ
fnp-3050	70	20	than	than	ADP
fnp-3050	70	21	10	10	NUM
fnp-3050	70	22	%	%	NOUN
fnp-3050	70	23	)	)	PUNCT
fnp-3050	70	24	.	.	PUNCT
fnp-3050	71	1	aβ-40	aβ-40	PUNCT
fnp-3050	71	2	is	be	AUX
fnp-3050	71	3	produced	produce	VERB
fnp-3050	71	4	within	within	ADP
fnp-3050	71	5	the	the	DET
fnp-3050	71	6	trans	trans	ADJ
fnp-3050	71	7	-	-	PROPN
fnp-3050	71	8	golgi	golgi	PROPN
fnp-3050	71	9	network	network	NOUN
fnp-3050	71	10	(	(	PUNCT
fnp-3050	71	11	tgn	tgn	NOUN
fnp-3050	71	12	)	)	PUNCT
fnp-3050	71	13	whilst	whilst	SCONJ
fnp-3050	71	14	aβ-42	aβ-42	NOUN
fnp-3050	71	15	can	can	AUX
fnp-3050	71	16	be	be	AUX
fnp-3050	71	17	made	make	VERB
fnp-3050	71	18	in	in	ADP
fnp-3050	71	19	either	either	CCONJ
fnp-3050	71	20	the	the	DET
fnp-3050	71	21	tgn	tgn	NOUN
fnp-3050	71	22	or	or	CCONJ
fnp-3050	71	23	the	the	DET
fnp-3050	71	24	endoplasmic	endoplasmic	ADJ
fnp-3050	71	25	reticulum	reticulum	NOUN
fnp-3050	71	26	[	[	X
fnp-3050	71	27	48	48	NUM
fnp-3050	71	28	]	]	PUNCT
fnp-3050	71	29	.	.	PUNCT
fnp-3050	72	1	the	the	DET
fnp-3050	72	2	specific	specific	ADJ
fnp-3050	72	3	production	production	NOUN
fnp-3050	72	4	of	of	ADP
fnp-3050	72	5	aβ-42	aβ-42	NOUN
fnp-3050	72	6	in	in	ADP
fnp-3050	72	7	the	the	DET
fnp-3050	72	8	endoplasmic	endoplasmic	ADJ
fnp-3050	72	9	reticulum	reticulum	NOUN
fnp-3050	72	10	of	of	ADP
fnp-3050	72	11	neurons	neuron	NOUN
fnp-3050	72	12	links	link	NOUN
fnp-3050	72	13	this	this	DET
fnp-3050	72	14	compartment	compartment	NOUN
fnp-3050	72	15	with	with	ADP
fnp-3050	72	16	the	the	DET
fnp-3050	72	17	generation	generation	NOUN
fnp-3050	72	18	of	of	ADP
fnp-3050	72	19	aβ	aβ	NOUN
fnp-3050	72	20	and	and	CCONJ
fnp-3050	72	21	explains	explain	VERB
fnp-3050	72	22	why	why	SCONJ
fnp-3050	72	23	primarily	primarily	ADV
fnp-3050	72	24	endoplasmic	endoplasmic	ADJ
fnp-3050	72	25	reticulum	reticulum	NOUN
fnp-3050	72	26	localized	localize	VERB
fnp-3050	72	27	proteins	protein	NOUN
fnp-3050	72	28	such	such	ADJ
fnp-3050	72	29	as	as	ADP
fnp-3050	72	30	presenilin	presenilin	PROPN
fnp-3050	72	31	could	could	AUX
fnp-3050	72	32	induce	induce	VERB
fnp-3050	72	33	ad	ad	NOUN
fnp-3050	72	34	[	[	X
fnp-3050	72	35	49	49	NUM
fnp-3050	72	36	]	]	PUNCT
fnp-3050	72	37	.	.	PUNCT
fnp-3050	73	1	increased	increase	VERB
fnp-3050	73	2	production	production	NOUN
fnp-3050	73	3	of	of	ADP
fnp-3050	73	4	aβ-42	aβ-42	NOUN
fnp-3050	73	5	at	at	ADP
fnp-3050	73	6	the	the	DET
fnp-3050	73	7	expense	expense	NOUN
fnp-3050	73	8	of	of	ADP
fnp-3050	73	9	aβ-40	aβ-40	NOUN
fnp-3050	73	10	is	be	AUX
fnp-3050	73	11	a	a	DET
fnp-3050	73	12	common	common	ADJ
fnp-3050	73	13	feature	feature	NOUN
fnp-3050	73	14	in	in	ADP
fnp-3050	73	15	both	both	CCONJ
fnp-3050	73	16	familial	familial	ADJ
fnp-3050	73	17	and	and	CCONJ
fnp-3050	73	18	sporadic	sporadic	ADJ
fnp-3050	73	19	ad	ad	NOUN
fnp-3050	73	20	[	[	X
fnp-3050	73	21	50	50	NUM
fnp-3050	73	22	]	]	PUNCT
fnp-3050	73	23	.	.	PUNCT
fnp-3050	74	1	the	the	DET
fnp-3050	74	2	latter	latter	ADJ
fnp-3050	74	3	is	be	AUX
fnp-3050	74	4	believed	believe	VERB
fnp-3050	74	5	to	to	PART
fnp-3050	74	6	be	be	AUX
fnp-3050	74	7	more	more	ADV
fnp-3050	74	8	toxic	toxic	ADJ
fnp-3050	74	9	than	than	ADP
fnp-3050	74	10	aβ-40	aβ-40	NOUN
fnp-3050	74	11	because	because	SCONJ
fnp-3050	74	12	of	of	ADP
fnp-3050	74	13	its	its	PRON
fnp-3050	74	14	tendency	tendency	NOUN
fnp-3050	74	15	to	to	PART
fnp-3050	74	16	aggregate	aggregate	VERB
fnp-3050	74	17	and	and	CCONJ
fnp-3050	74	18	to	to	PART
fnp-3050	74	19	form	form	VERB
fnp-3050	74	20	fibrils	fibril	NOUN
fnp-3050	74	21	[	[	X
fnp-3050	74	22	51	51	NUM
fnp-3050	74	23	]	]	PUNCT
fnp-3050	74	24	.	.	PUNCT
fnp-3050	75	1	the	the	DET
fnp-3050	75	2	phosphorylation	phosphorylation	NOUN
fnp-3050	75	3	of	of	ADP
fnp-3050	75	4	app	app	NOUN
fnp-3050	75	5	by	by	ADP
fnp-3050	75	6	extracellular	extracellular	ADJ
fnp-3050	75	7	-	-	PUNCT
fnp-3050	75	8	regulated	regulate	VERB
fnp-3050	75	9	kinase	kinase	NOUN
fnp-3050	75	10	(	(	PUNCT
fnp-3050	75	11	erk	erk	PROPN
fnp-3050	75	12	)	)	PUNCT
fnp-3050	75	13	and	and	CCONJ
fnp-3050	75	14	protein	protein	NOUN
fnp-3050	75	15	kinase	kinase	PROPN
fnp-3050	75	16	c	c	PROPN
fnp-3050	75	17	(	(	PUNCT
fnp-3050	75	18	pkc	pkc	PROPN
fnp-3050	75	19	)	)	PUNCT
fnp-3050	75	20	,	,	PUNCT
fnp-3050	75	21	in	in	ADP
fnp-3050	75	22	the	the	DET
fnp-3050	75	23	proteolytic	proteolytic	ADJ
fnp-3050	75	24	processing	processing	NOUN
fnp-3050	75	25	of	of	ADP
fnp-3050	75	26	app	app	NOUN
fnp-3050	75	27	has	have	AUX
fnp-3050	75	28	been	be	AUX
fnp-3050	75	29	demonstrated	demonstrate	VERB
fnp-3050	75	30	to	to	PART
fnp-3050	75	31	be	be	AUX
fnp-3050	75	32	critically	critically	ADV
fnp-3050	75	33	modulating	modulate	VERB
fnp-3050	75	34	the	the	DET
fnp-3050	75	35	generation	generation	NOUN
fnp-3050	75	36	of	of	ADP
fnp-3050	75	37	aβ	aβ	NOUN
fnp-3050	76	1	[	[	X
fnp-3050	76	2	52	52	NUM
fnp-3050	76	3	]	]	PUNCT
fnp-3050	76	4	.	.	PUNCT
fnp-3050	77	1	the	the	DET
fnp-3050	77	2	c	c	NOUN
fnp-3050	77	3	-	-	PUNCT
fnp-3050	77	4	terminal	terminal	ADJ
fnp-3050	77	5	app	app	NOUN
fnp-3050	77	6	fragments	fragment	NOUN
fnp-3050	77	7	(	(	PUNCT
fnp-3050	77	8	app	app	X
fnp-3050	77	9	intracellular	intracellular	ADJ
fnp-3050	77	10	domain	domain	NOUN
fnp-3050	77	11	)	)	PUNCT
fnp-3050	77	12	are	be	AUX
fnp-3050	77	13	generated	generate	VERB
fnp-3050	77	14	by	by	ADP
fnp-3050	77	15	γ	γ	PROPN
fnp-3050	77	16	-	-	PUNCT
fnp-3050	77	17	secretase	secretase	ADJ
fnp-3050	77	18	cleavage	cleavage	NOUN
fnp-3050	77	19	[	[	X
fnp-3050	77	20	53	53	NUM
fnp-3050	77	21	]	]	PUNCT
fnp-3050	77	22	.	.	PUNCT
fnp-3050	78	1	γ	γ	X
fnp-3050	78	2	-	-	PUNCT
fnp-3050	78	3	secretase	secretase	NOUN
fnp-3050	78	4	was	be	AUX
fnp-3050	78	5	shown	show	VERB
fnp-3050	78	6	to	to	PART
fnp-3050	78	7	cleave	cleave	VERB
fnp-3050	78	8	near	near	ADP
fnp-3050	78	9	the	the	DET
fnp-3050	78	10	cytoplasmic	cytoplasmic	ADJ
fnp-3050	78	11	membrane	membrane	NOUN
fnp-3050	78	12	boundary	boundary	NOUN
fnp-3050	78	13	of	of	ADP
fnp-3050	78	14	app	app	PROPN
fnp-3050	78	15	,	,	PUNCT
fnp-3050	78	16	called	call	VERB
fnp-3050	78	17	ε	ε	NOUN
fnp-3050	78	18	-	-	PUNCT
fnp-3050	78	19	site	site	NOUN
fnp-3050	78	20	cleavage	cleavage	NOUN
fnp-3050	78	21	,	,	PUNCT
fnp-3050	78	22	as	as	ADV
fnp-3050	78	23	well	well	ADV
fnp-3050	78	24	as	as	ADP
fnp-3050	78	25	in	in	ADP
fnp-3050	78	26	the	the	DET
fnp-3050	78	27	middle	middle	NOUN
fnp-3050	78	28	of	of	ADP
fnp-3050	78	29	the	the	DET
fnp-3050	78	30	membrane	membrane	NOUN
fnp-3050	78	31	domain	domain	NOUN
fnp-3050	78	32	,	,	PUNCT
fnp-3050	78	33	called	call	VERB
fnp-3050	78	34	γ	γ	NOUN
fnp-3050	78	35	-	-	PUNCT
fnp-3050	78	36	site	site	NOUN
fnp-3050	78	37	cleavage	cleavage	NOUN
fnp-3050	78	38	,	,	PUNCT
fnp-3050	78	39	indicating	indicate	VERB
fnp-3050	78	40	that	that	SCONJ
fnp-3050	78	41	γand	γand	NOUN
fnp-3050	78	42	ε	ε	PROPN
fnp-3050	78	43	-	-	PUNCT
fnp-3050	78	44	site	site	NOUN
fnp-3050	78	45	cleavage	cleavage	NOUN
fnp-3050	78	46	are	be	AUX
fnp-3050	78	47	regulated	regulate	VERB
fnp-3050	78	48	independently	independently	ADV
fnp-3050	78	49	[	[	X
fnp-3050	78	50	54	54	NUM
fnp-3050	78	51	]	]	X
fnp-3050	78	52	.	.	PUNCT
fnp-3050	79	1	ubiquilin-1	ubiquilin-1	NUM
fnp-3050	79	2	has	have	AUX
fnp-3050	79	3	been	be	AUX
fnp-3050	79	4	shown	show	VERB
fnp-3050	79	5	to	to	PART
fnp-3050	79	6	modulate	modulate	VERB
fnp-3050	79	7	γ	γ	NOUN
fnp-3050	79	8	-	-	PUNCT
fnp-3050	79	9	secretase	secretase	NOUN
fnp-3050	79	10	-	-	PUNCT
fnp-3050	79	11	mediated	mediate	VERB
fnp-3050	79	12	ε	ε	NOUN
fnp-3050	79	13	-	-	PUNCT
fnp-3050	79	14	site	site	NOUN
fnp-3050	79	15	cleavage	cleavage	NOUN
fnp-3050	79	16	and	and	CCONJ
fnp-3050	79	17	thus	thus	ADV
fnp-3050	79	18	may	may	AUX
fnp-3050	79	19	play	play	VERB
fnp-3050	79	20	a	a	DET
fnp-3050	79	21	role	role	NOUN
fnp-3050	79	22	in	in	ADP
fnp-3050	79	23	regulating	regulate	VERB
fnp-3050	79	24	γ	γ	PROPN
fnp-3050	79	25	-	-	ADJ
fnp-3050	79	26	secretase	secretase	ADJ
fnp-3050	79	27	cleavage	cleavage	NOUN
fnp-3050	79	28	of	of	ADP
fnp-3050	79	29	app	app	NOUN
fnp-3050	79	30	and	and	CCONJ
fnp-3050	79	31	other	other	ADJ
fnp-3050	79	32	proteins	protein	NOUN
fnp-3050	79	33	[	[	X
fnp-3050	79	34	55	55	NUM
fnp-3050	79	35	]	]	PUNCT
fnp-3050	79	36	.	.	PUNCT
fnp-3050	80	1	further	further	ADJ
fnp-3050	80	2	cleavage	cleavage	NOUN
fnp-3050	80	3	of	of	ADP
fnp-3050	80	4	app	app	NOUN
fnp-3050	80	5	intracellular	intracellular	ADJ
fnp-3050	80	6	domain	domain	NOUN
fnp-3050	80	7	(	(	PUNCT
fnp-3050	80	8	aicd	aicd	NOUN
fnp-3050	80	9	)	)	PUNCT
fnp-3050	80	10	fragments	fragment	NOUN
fnp-3050	80	11	by	by	ADP
fnp-3050	80	12	caspase	caspase	NOUN
fnp-3050	80	13	or	or	CCONJ
fnp-3050	80	14	caspase	caspase	NOUN
fnp-3050	80	15	-	-	PUNCT
fnp-3050	80	16	like	like	ADJ
fnp-3050	80	17	proteases	protease	NOUN
fnp-3050	80	18	results	result	VERB
fnp-3050	80	19	in	in	ADP
fnp-3050	80	20	additional	additional	ADJ
fnp-3050	80	21	fragments	fragment	NOUN
fnp-3050	80	22	which	which	PRON
fnp-3050	80	23	,	,	PUNCT
fnp-3050	80	24	however	however	ADV
fnp-3050	80	25	,	,	PUNCT
fnp-3050	80	26	does	do	AUX
fnp-3050	80	27	not	not	PART
fnp-3050	80	28	seem	seem	VERB
fnp-3050	80	29	to	to	PART
fnp-3050	80	30	require	require	VERB
fnp-3050	80	31	antecedent	antecedent	NOUN
fnp-3050	80	32	proteolysis	proteolysis	NOUN
fnp-3050	80	33	of	of	ADP
fnp-3050	80	34	app	app	NOUN
fnp-3050	80	35	[	[	X
fnp-3050	80	36	41	41	NUM
fnp-3050	80	37	]	]	PUNCT
fnp-3050	80	38	.	.	PUNCT
fnp-3050	81	1	figure	figure	NOUN
fnp-3050	81	2	2	2	NUM
fnp-3050	81	3	.	.	PUNCT
fnp-3050	82	1	amyloid	amyloid	NOUN
fnp-3050	82	2	and	and	CCONJ
fnp-3050	82	3	neuritic	neuritic	ADJ
fnp-3050	82	4	plaques	plaque	NOUN
fnp-3050	82	5	.	.	PUNCT
fnp-3050	83	1	a	a	DET
fnp-3050	83	2	;	;	PUNCT
fnp-3050	83	3	a1	a1	NOUN
fnp-3050	83	4	.	.	PROPN
fnp-3050	83	5	multiple	multiple	ADJ
fnp-3050	83	6	diffuse	diffuse	ADJ
fnp-3050	83	7	amyloid	amyloid	NOUN
fnp-3050	83	8	plaques	plaque	NOUN
fnp-3050	83	9	in	in	ADP
fnp-3050	83	10	the	the	DET
fnp-3050	83	11	neocortex	neocortex	NOUN
fnp-3050	83	12	(	(	PUNCT
fnp-3050	83	13	antibody	antibody	NOUN
fnp-3050	83	14	4g8	4g8	NUM
fnp-3050	83	15	)	)	PUNCT
fnp-3050	83	16	.	.	PUNCT
fnp-3050	84	1	b	b	X
fnp-3050	84	2	,	,	PUNCT
fnp-3050	84	3	b1	b1	NOUN
fnp-3050	84	4	.	.	PUNCT
fnp-3050	85	1	neuritic	neuritic	ADJ
fnp-3050	85	2	plaques	plaque	NOUN
fnp-3050	85	3	that	that	PRON
fnp-3050	85	4	contain	contain	VERB
fnp-3050	85	5	aβ	aβ	PRON
fnp-3050	85	6	and	and	CCONJ
fnp-3050	85	7	tau	tau	PROPN
fnp-3050	85	8	in	in	ADP
fnp-3050	85	9	distended	distend	VERB
fnp-3050	85	10	processes	process	NOUN
fnp-3050	85	11	(	(	PUNCT
fnp-3050	85	12	i.e.	i.e.	X
fnp-3050	85	13	dystrophic	dystrophic	ADJ
fnp-3050	85	14	neurites	neurite	NOUN
fnp-3050	85	15	)	)	PUNCT
fnp-3050	85	16	.	.	PUNCT
fnp-3050	86	1	gallyas	gallyas	NOUN
fnp-3050	86	2	silver	silver	NOUN
fnp-3050	86	3	stain	stain	NOUN
fnp-3050	86	4	visualizes	visualize	VERB
fnp-3050	86	5	both	both	PRON
fnp-3050	86	6	aggregated	aggregate	VERB
fnp-3050	86	7	aβ	aβ	ADP
fnp-3050	86	8	and	and	CCONJ
fnp-3050	86	9	tau	tau	PROPN
fnp-3050	86	10	and	and	CCONJ
fnp-3050	86	11	is	be	AUX
fnp-3050	86	12	therefore	therefore	ADV
fnp-3050	86	13	ideal	ideal	ADJ
fnp-3050	86	14	to	to	PART
fnp-3050	86	15	detect	detect	VERB
fnp-3050	86	16	neuritic	neuritic	ADJ
fnp-3050	86	17	plaques	plaque	NOUN
fnp-3050	86	18	(	(	PUNCT
fnp-3050	86	19	ring	ring	NOUN
fnp-3050	86	20	in	in	ADP
fnp-3050	86	21	b	b	PROPN
fnp-3050	86	22	,	,	PUNCT
fnp-3050	86	23	neuritic	neuritic	ADJ
fnp-3050	86	24	plaque	plaque	NOUN
fnp-3050	86	25	;	;	PUNCT
fnp-3050	86	26	arrow	arrow	NOUN
fnp-3050	86	27	in	in	ADP
fnp-3050	86	28	b1	b1	PROPN
fnp-3050	86	29	,	,	PUNCT
fnp-3050	86	30	dystrophic	dystrophic	ADJ
fnp-3050	86	31	neurite	neurite	NOUN
fnp-3050	86	32	;	;	PUNCT
fnp-3050	86	33	arrowhead	arrowhead	NOUN
fnp-3050	86	34	in	in	ADP
fnp-3050	86	35	b1	b1	NOUN
fnp-3050	86	36	,	,	PUNCT
fnp-3050	86	37	neurofibrillary	neurofibrillary	ADJ
fnp-3050	86	38	tangle	tangle	NOUN
fnp-3050	86	39	)	)	PUNCT
fnp-3050	86	40	.	.	PUNCT
fnp-3050	87	1	scale	scale	NOUN
fnp-3050	87	2	bars	bar	NOUN
fnp-3050	87	3	:	:	PUNCT
fnp-3050	87	4	200	200	NUM
fnp-3050	87	5	μm	μm	NOUN
fnp-3050	87	6	.	.	PUNCT
fnp-3050	87	7	from	from	ADP
fnp-3050	87	8	[	[	X
fnp-3050	87	9	71	71	NUM
fnp-3050	87	10	]	]	PUNCT
fnp-3050	87	11	.	.	PUNCT
fnp-3050	88	1	truncated	truncate	VERB
fnp-3050	88	2	aβ	aβ	NOUN
fnp-3050	88	3	fragments	fragment	NOUN
fnp-3050	88	4	are	be	AUX
fnp-3050	88	5	deposited	deposit	VERB
fnp-3050	88	6	in	in	ADP
fnp-3050	88	7	aps	ap	NOUN
fnp-3050	88	8	due	due	ADP
fnp-3050	88	9	to	to	ADP
fnp-3050	88	10	axonal	axonal	ADJ
fnp-3050	88	11	linkage	linkage	NOUN
fnp-3050	88	12	and	and	CCONJ
fnp-3050	88	13	release	release	NOUN
fnp-3050	88	14	of	of	ADP
fnp-3050	88	15	app	app	NOUN
fnp-3050	89	1	[	[	X
fnp-3050	89	2	56	56	NUM
fnp-3050	89	3	]	]	PUNCT
fnp-3050	89	4	.	.	PUNCT
fnp-3050	90	1	chemical	chemical	ADJ
fnp-3050	90	2	imaging	imaging	NOUN
fnp-3050	90	3	of	of	ADP
fnp-3050	90	4	evolving	evolve	VERB
fnp-3050	90	5	ap	ap	PROPN
fnp-3050	90	6	pathology	pathology	NOUN
fnp-3050	90	7	in	in	ADP
fnp-3050	90	8	a	a	DET
fnp-3050	90	9	transgenic	transgenic	NOUN
fnp-3050	90	10	mouse	mouse	NOUN
fnp-3050	90	11	model	model	NOUN
fnp-3050	90	12	for	for	ADP
fnp-3050	90	13	ad	ad	NOUN
fnp-3050	90	14	suggested	suggest	VERB
fnp-3050	90	15	initial	initial	ADJ
fnp-3050	90	16	plaque	plaque	NOUN
fnp-3050	90	17	formation	formation	NOUN
fnp-3050	90	18	to	to	PART
fnp-3050	90	19	be	be	AUX
fnp-3050	90	20	seeded	seed	VERB
fnp-3050	90	21	by	by	ADP
fnp-3050	90	22	aβ-42	aβ-42	NOUN
fnp-3050	90	23	,	,	PUNCT
fnp-3050	90	24	followed	follow	VERB
fnp-3050	90	25	by	by	ADP
fnp-3050	90	26	plaque	plaque	NOUN
fnp-3050	90	27	maturation	maturation	NOUN
fnp-3050	90	28	upon	upon	SCONJ
fnp-3050	90	29	deposition	deposition	NOUN
fnp-3050	90	30	of	of	ADP
fnp-3050	90	31	aβ-40	aβ-40	NOUN
fnp-3050	90	32	as	as	ADV
fnp-3050	90	33	well	well	ADV
fnp-3050	90	34	as	as	ADP
fnp-3050	90	35	deposition	deposition	NOUN
fnp-3050	90	36	of	of	ADP
fnp-3050	90	37	others	other	NOUN
fnp-3050	90	38	[	[	X
fnp-3050	90	39	57	57	NUM
fnp-3050	90	40	]	]	PUNCT
fnp-3050	90	41	.	.	PUNCT
fnp-3050	91	1	due	due	ADP
fnp-3050	91	2	to	to	ADP
fnp-3050	91	3	its	its	PRON
fnp-3050	91	4	higher	high	ADJ
fnp-3050	91	5	rate	rate	NOUN
fnp-3050	91	6	of	of	ADP
fnp-3050	91	7	fibrillization	fibrillization	NOUN
fnp-3050	91	8	and	and	CCONJ
fnp-3050	91	9	insolubility	insolubility	NOUN
fnp-3050	91	10	,	,	PUNCT
fnp-3050	91	11	aβ-42	aβ-42	ADV
fnp-3050	91	12	is	be	AUX
fnp-3050	91	13	its	its	PRON
fnp-3050	91	14	major	major	ADJ
fnp-3050	91	15	component	component	NOUN
fnp-3050	91	16	in	in	ADP
fnp-3050	91	17	addition	addition	NOUN
fnp-3050	91	18	to	to	ADP
fnp-3050	91	19	other	other	ADJ
fnp-3050	91	20	aβ	aβ	NOUN
fnp-3050	91	21	peptides	peptide	NOUN
fnp-3050	91	22	[	[	X
fnp-3050	91	23	58	58	NUM
fnp-3050	91	24	]	]	PUNCT
fnp-3050	91	25	.	.	PUNCT
fnp-3050	92	1	a	a	DET
fnp-3050	92	2	recent	recent	ADJ
fnp-3050	92	3	report	report	NOUN
fnp-3050	92	4	demonstrated	demonstrate	VERB
fnp-3050	92	5	the	the	DET
fnp-3050	92	6	role	role	NOUN
fnp-3050	92	7	of	of	ADP
fnp-3050	92	8	hif-1alpha	hif-1alpha	NOUN
fnp-3050	92	9	/	/	SYM
fnp-3050	92	10	lncrna	lncrna	NOUN
fnp-3050	92	11	bace1	bace1	NOUN
fnp-3050	92	12	-	-	PUNCT
fnp-3050	92	13	as	as	ADV
fnp-3050	92	14	axis	axis	NOUN
fnp-3050	92	15	in	in	ADP
fnp-3050	92	16	the	the	DET
fnp-3050	92	17	transactivator	transactivator	NOUN
fnp-3050	92	18	of	of	ADP
fnp-3050	92	19	transcription	transcription	NOUN
fnp-3050	92	20	(	(	PUNCT
fnp-3050	92	21	tat)-mediated	tat)-mediate	VERB
fnp-3050	92	22	induction	induction	NOUN
fnp-3050	92	23	of	of	ADP
fnp-3050	92	24	astrocytic	astrocytic	ADJ
fnp-3050	92	25	amyloidosis	amyloidosis	NOUN
fnp-3050	92	26	[	[	X
fnp-3050	92	27	59	59	NUM
fnp-3050	92	28	]	]	PUNCT
fnp-3050	92	29	.	.	PUNCT
fnp-3050	93	1	advanced	advanced	ADJ
fnp-3050	93	2	biophysical	biophysical	ADJ
fnp-3050	93	3	examination	examination	NOUN
fnp-3050	93	4	of	of	ADP
fnp-3050	93	5	aβ	aβ	PRON
fnp-3050	93	6	derived	derive	VERB
fnp-3050	93	7	from	from	ADP
fnp-3050	93	8	ad	ad	NOUN
fnp-3050	93	9	brain	brain	NOUN
fnp-3050	93	10	tissue	tissue	NOUN
fnp-3050	93	11	showed	show	VERB
fnp-3050	93	12	polymorphic	polymorphic	ADJ
fnp-3050	93	13	structures	structure	NOUN
fnp-3050	93	14	[	[	X
fnp-3050	93	15	60	60	NUM
fnp-3050	93	16	]	]	PUNCT
fnp-3050	93	17	.	.	PUNCT
fnp-3050	94	1	the	the	DET
fnp-3050	94	2	terminology	terminology	NOUN
fnp-3050	94	3	of	of	ADP
fnp-3050	94	4	aβ	aβ	DET
fnp-3050	94	5	plaques	plaque	NOUN
fnp-3050	94	6	is	be	AUX
fnp-3050	94	7	confusing	confusing	ADJ
fnp-3050	94	8	,	,	PUNCT
fnp-3050	94	9	since	since	SCONJ
fnp-3050	94	10	a	a	DET
fnp-3050	94	11	myriad	myriad	NOUN
fnp-3050	94	12	of	of	ADP
fnp-3050	94	13	non	non	ADJ
fnp-3050	94	14	-	-	ADJ
fnp-3050	94	15	vascular	vascular	ADJ
fnp-3050	94	16	aβ	aβ	NOUN
fnp-3050	94	17	deposits	deposit	NOUN
fnp-3050	94	18	have	have	AUX
fnp-3050	94	19	been	be	AUX
fnp-3050	94	20	described	describe	VERB
fnp-3050	94	21	,	,	PUNCT
fnp-3050	94	22	but	but	CCONJ
fnp-3050	94	23	five	five	NUM
fnp-3050	94	24	major	major	ADJ
fnp-3050	94	25	types	type	NOUN
fnp-3050	94	26	can	can	AUX
fnp-3050	94	27	be	be	AUX
fnp-3050	94	28	distinguished	distinguish	VERB
fnp-3050	94	29	:	:	PUNCT
fnp-3050	94	30	(	(	PUNCT
fnp-3050	94	31	a	a	X
fnp-3050	94	32	)	)	PUNCT
fnp-3050	94	33	primitive	primitive	ADJ
fnp-3050	94	34	or	or	CCONJ
fnp-3050	94	35	immature	immature	ADJ
fnp-3050	94	36	plaques	plaque	NOUN
fnp-3050	94	37	are	be	AUX
fnp-3050	94	38	spherical	spherical	ADJ
fnp-3050	94	39	deposits	deposit	NOUN
fnp-3050	94	40	of	of	ADP
fnp-3050	94	41	predominantly	predominantly	ADV
fnp-3050	94	42	aβ-42	aβ-42	ADV
fnp-3050	94	43	in	in	ADP
fnp-3050	94	44	the	the	DET
fnp-3050	94	45	neuropil	neuropil	NOUN
fnp-3050	94	46	without	without	ADP
fnp-3050	94	47	a	a	DET
fnp-3050	94	48	dense	dense	ADJ
fnp-3050	94	49	core	core	NOUN
fnp-3050	94	50	and	and	CCONJ
fnp-3050	94	51	neurites	neurite	NOUN
fnp-3050	94	52	;	;	PUNCT
fnp-3050	94	53	(	(	PUNCT
fnp-3050	94	54	b	b	X
fnp-3050	94	55	)	)	PUNCT
fnp-3050	94	56	diffuse	diffuse	ADJ
fnp-3050	94	57	plaques	plaque	NOUN
fnp-3050	94	58	,	,	PUNCT
fnp-3050	94	59	usually	usually	ADV
fnp-3050	94	60	large	large	ADJ
fnp-3050	94	61	(	(	PUNCT
fnp-3050	94	62	50	50	NUM
fnp-3050	94	63	µm	µm	NOUN
fnp-3050	94	64	to	to	ADP
fnp-3050	94	65	several	several	ADJ
fnp-3050	94	66	hundred	hundred	NUM
fnp-3050	94	67	µm	µm	NUM
fnp-3050	94	68	)	)	PUNCT
fnp-3050	94	69	,	,	PUNCT
fnp-3050	94	70	slightly	slightly	ADV
fnp-3050	94	71	immunoreactive	immunoreactive	ADJ
fnp-3050	94	72	and	and	CCONJ
fnp-3050	94	73	ill	ill	ADV
fnp-3050	94	74	-	-	PUNCT
fnp-3050	94	75	limited	limited	ADJ
fnp-3050	94	76	,	,	PUNCT
fnp-3050	94	77	contain	contain	VERB
fnp-3050	94	78	loose	loose	ADJ
fnp-3050	94	79	amyloid	amyloid	NOUN
fnp-3050	94	80	bundles	bundle	NOUN
fnp-3050	94	81	in	in	ADP
fnp-3050	94	82	the	the	DET
fnp-3050	94	83	neuropil	neuropil	NOUN
fnp-3050	94	84	without	without	ADP
fnp-3050	94	85	degenerating	degenerate	VERB
fnp-3050	94	86	neurites	neurite	NOUN
fnp-3050	94	87	and	and	CCONJ
fnp-3050	94	88	accompanying	accompany	VERB
fnp-3050	94	89	microglia	microglia	NOUN
fnp-3050	94	90	(	(	PUNCT
fnp-3050	94	91	fig	fig	NOUN
fnp-3050	94	92	.	.	PUNCT
fnp-3050	94	93	2a	2a	NUM
fnp-3050	94	94	)	)	PUNCT
fnp-3050	94	95	;	;	PUNCT
fnp-3050	94	96	(	(	PUNCT
fnp-3050	94	97	c	c	X
fnp-3050	94	98	)	)	PUNCT
fnp-3050	94	99	stellate	stellate	ADJ
fnp-3050	94	100	deposits	deposit	NOUN
fnp-3050	94	101	probably	probably	ADV
fnp-3050	94	102	related	relate	VERB
fnp-3050	94	103	to	to	ADP
fnp-3050	94	104	astrocytes	astrocyte	NOUN
fnp-3050	94	105	[	[	X
fnp-3050	94	106	61	61	NUM
fnp-3050	94	107	]	]	PUNCT
fnp-3050	94	108	;	;	PUNCT
fnp-3050	94	109	(	(	PUNCT
fnp-3050	94	110	d	d	X
fnp-3050	94	111	)	)	PUNCT
fnp-3050	94	112	focal	focal	ADJ
fnp-3050	94	113	deposits	deposit	NOUN
fnp-3050	94	114	with	with	ADP
fnp-3050	94	115	dense	dense	ADJ
fnp-3050	94	116	and	and	CCONJ
fnp-3050	94	117	spherical	spherical	ADJ
fnp-3050	94	118	accumulations	accumulation	NOUN
fnp-3050	94	119	of	of	ADP
fnp-3050	94	120	aβ-42	aβ-42	PRON
fnp-3050	94	121	,	,	PUNCT
fnp-3050	94	122	surrounded	surround	VERB
fnp-3050	94	123	by	by	ADP
fnp-3050	94	124	a	a	DET
fnp-3050	94	125	neuritic	neuritic	ADJ
fnp-3050	94	126	corona	corona	NOUN
fnp-3050	94	127	containing	contain	VERB
fnp-3050	94	128	dystrophic	dystrophic	ADJ
fnp-3050	94	129	tau	tau	PROPN
fnp-3050	94	130	-	-	PUNCT
fnp-3050	94	131	positive	positive	ADJ
fnp-3050	94	132	neurites	neurite	NOUN
fnp-3050	94	133	and	and	CCONJ
fnp-3050	94	134	astrocytic	astrocytic	ADJ
fnp-3050	94	135	components	component	NOUN
fnp-3050	94	136	,	,	PUNCT
fnp-3050	94	137	constituting	constitute	VERB
fnp-3050	94	138	the	the	DET
fnp-3050	94	139	“	"	PUNCT
fnp-3050	94	140	cored	core	VERB
fnp-3050	94	141	”	"	PUNCT
fnp-3050	94	142	,	,	PUNCT
fnp-3050	94	143	“	"	PUNCT
fnp-3050	94	144	classical	classical	ADJ
fnp-3050	94	145	”	"	PUNCT
fnp-3050	94	146	or	or	CCONJ
fnp-3050	94	147	“	"	PUNCT
fnp-3050	94	148	neuritic	neuritic	ADJ
fnp-3050	94	149	”	"	PUNCT
fnp-3050	94	150	plaques	plaque	NOUN
fnp-3050	94	151	(	(	PUNCT
fnp-3050	94	152	nps	nps	PROPN
fnp-3050	94	153	)	)	PUNCT
fnp-3050	94	154	(	(	PUNCT
fnp-3050	94	155	fig	fig	NOUN
fnp-3050	94	156	.	.	PUNCT
fnp-3050	94	157	2b	2b	NOUN
fnp-3050	94	158	,	,	PUNCT
fnp-3050	94	159	2b1	2b1	NUM
fnp-3050	94	160	)	)	PUNCT
fnp-3050	94	161	;	;	PUNCT
fnp-3050	94	162	and	and	CCONJ
fnp-3050	94	163	finally	finally	ADV
fnp-3050	94	164	(	(	PUNCT
fnp-3050	94	165	e	e	NOUN
fnp-3050	94	166	)	)	PUNCT
fnp-3050	94	167	compact	compact	ADJ
fnp-3050	94	168	or	or	CCONJ
fnp-3050	94	169	burnt	burn	VERB
fnp-3050	94	170	-	-	PUNCT
fnp-3050	94	171	out	out	ADP
fnp-3050	94	172	plaques	plaque	NOUN
fnp-3050	94	173	with	with	ADP
fnp-3050	94	174	a	a	DET
fnp-3050	94	175	dense	dense	ADJ
fnp-3050	94	176	core	core	NOUN
fnp-3050	94	177	of	of	ADP
fnp-3050	94	178	aβ-40	aβ-40	PRON
fnp-3050	94	179	,	,	PUNCT
fnp-3050	94	180	absent	absent	ADJ
fnp-3050	94	181	or	or	CCONJ
fnp-3050	94	182	tau	tau	NOUN
fnp-3050	94	183	-	-	PUNCT
fnp-3050	94	184	negative	negative	ADJ
fnp-3050	94	185	,	,	PUNCT
fnp-3050	94	186	ubiquitin	ubiquitin	ADJ
fnp-3050	94	187	-	-	PUNCT
fnp-3050	94	188	positive	positive	ADJ
fnp-3050	94	189	neurites	neurite	NOUN
fnp-3050	94	190	.	.	PUNCT
fnp-3050	95	1	nps	nps	PROPN
fnp-3050	95	2	have	have	VERB
fnp-3050	95	3	compact	compact	ADJ
fnp-3050	95	4	dense	dense	ADJ
fnp-3050	95	5	amyloid	amyloid	NOUN
fnp-3050	95	6	cores	core	NOUN
fnp-3050	95	7	composed	compose	VERB
fnp-3050	95	8	of	of	ADP
fnp-3050	95	9	more	more	ADJ
fnp-3050	95	10	fibrillated	fibrillate	VERB
fnp-3050	95	11	forms	form	NOUN
fnp-3050	95	12	of	of	ADP
fnp-3050	95	13	aβ	aβ	PROPN
fnp-3050	95	14	(	(	PUNCT
fnp-3050	95	15	fig	fig	NOUN
fnp-3050	95	16	.	.	PUNCT
fnp-3050	96	1	3	3	NUM
fnp-3050	96	2	)	)	PUNCT
fnp-3050	96	3	.	.	PUNCT
fnp-3050	97	1	they	they	PRON
fnp-3050	97	2	contain	contain	VERB
fnp-3050	97	3	tau	tau	NOUN
fnp-3050	97	4	-	-	PUNCT
fnp-3050	97	5	positive	positive	ADJ
fnp-3050	97	6	dystrophic	dystrophic	ADJ
fnp-3050	97	7	neurites	neurite	NOUN
fnp-3050	97	8	and	and	CCONJ
fnp-3050	97	9	are	be	AUX
fnp-3050	97	10	accompanied	accompany	VERB
fnp-3050	97	11	by	by	ADP
fnp-3050	97	12	synaptic	synaptic	ADJ
fnp-3050	97	13	loss	loss	NOUN
fnp-3050	97	14	,	,	PUNCT
fnp-3050	97	15	activated	activate	VERB
fnp-3050	97	16	microglia	microglia	ADJ
fnp-3050	97	17	and	and	CCONJ
fnp-3050	97	18	reactive	reactive	ADJ
fnp-3050	97	19	astrocytes	astrocyte	NOUN
fnp-3050	97	20	[	[	X
fnp-3050	97	21	62	62	NUM
fnp-3050	97	22	,	,	PUNCT
fnp-3050	97	23	63	63	NUM
fnp-3050	97	24	]	]	PUNCT
fnp-3050	97	25	.	.	PUNCT
fnp-3050	98	1	there	there	PRON
fnp-3050	98	2	are	be	VERB
fnp-3050	98	3	differences	difference	NOUN
fnp-3050	98	4	in	in	ADP
fnp-3050	98	5	the	the	DET
fnp-3050	98	6	composition	composition	NOUN
fnp-3050	98	7	of	of	ADP
fnp-3050	98	8	the	the	DET
fnp-3050	98	9	aggregates	aggregate	NOUN
fnp-3050	98	10	,	,	PUNCT
fnp-3050	98	11	for	for	ADP
fnp-3050	98	12	example	example	NOUN
fnp-3050	98	13	,	,	PUNCT
fnp-3050	98	14	the	the	DET
fnp-3050	98	15	aβ	aβ	NOUN
fnp-3050	98	16	in	in	ADP
fnp-3050	98	17	nps	nps	PROPN
fnp-3050	98	18	has	have	VERB
fnp-3050	98	19	a	a	DET
fnp-3050	98	20	more	more	ADV
fnp-3050	98	21	varied	varied	ADJ
fnp-3050	98	22	composition	composition	NOUN
fnp-3050	98	23	with	with	ADP
fnp-3050	98	24	the	the	DET
fnp-3050	98	25	presence	presence	NOUN
fnp-3050	98	26	of	of	ADP
fnp-3050	98	27	aβ	aβ	PRON
fnp-3050	98	28	40	40	NUM
fnp-3050	98	29	,	,	PUNCT
fnp-3050	98	30	42	42	NUM
fnp-3050	98	31	,	,	PUNCT
fnp-3050	98	32	43	43	NUM
fnp-3050	98	33	,	,	PUNCT
fnp-3050	98	34	n	n	CCONJ
fnp-3050	98	35	-	-	PUNCT
fnp-3050	98	36	terminus	terminus	NOUN
fnp-3050	98	37	truncated	truncate	VERB
fnp-3050	98	38	aβ	aβ	ADP
fnp-3050	98	39	and	and	CCONJ
fnp-3050	98	40	other	other	ADJ
fnp-3050	98	41	post	post	ADJ
fnp-3050	98	42	-	-	ADJ
fnp-3050	98	43	transitionally	transitionally	ADV
fnp-3050	98	44	modified	modify	VERB
fnp-3050	98	45	forms	form	NOUN
fnp-3050	98	46	[	[	X
fnp-3050	98	47	64	64	NUM
fnp-3050	98	48	,	,	PUNCT
fnp-3050	98	49	65	65	NUM
fnp-3050	98	50	]	]	PUNCT
fnp-3050	98	51	.	.	PUNCT
fnp-3050	99	1	tau	tau	NOUN
fnp-3050	99	2	-	-	PUNCT
fnp-3050	99	3	positive	positive	ADJ
fnp-3050	99	4	nps	nps	PROPN
fnp-3050	99	5	begin	begin	VERB
fnp-3050	99	6	early	early	ADV
fnp-3050	99	7	in	in	ADP
fnp-3050	99	8	ad	ad	NOUN
fnp-3050	99	9	,	,	PUNCT
fnp-3050	99	10	but	but	CCONJ
fnp-3050	99	11	major	major	ADJ
fnp-3050	99	12	tau	tau	PROPN
fnp-3050	99	13	deposition	deposition	NOUN
fnp-3050	99	14	follows	follow	VERB
fnp-3050	99	15	the	the	DET
fnp-3050	99	16	aβ	aβ	NOUN
fnp-3050	99	17	deposition	deposition	NOUN
fnp-3050	99	18	and	and	CCONJ
fnp-3050	99	19	the	the	DET
fnp-3050	99	20	clustering	clustering	NOUN
fnp-3050	99	21	of	of	ADP
fnp-3050	99	22	activated	activated	ADJ
fnp-3050	99	23	microglia	microglia	NOUN
fnp-3050	100	1	[	[	X
fnp-3050	100	2	66	66	NUM
fnp-3050	100	3	]	]	PUNCT
fnp-3050	100	4	.	.	PUNCT
fnp-3050	101	1	recent	recent	ADJ
fnp-3050	101	2	studies	study	NOUN
fnp-3050	101	3	unequivocally	unequivocally	ADV
fnp-3050	101	4	demonstrated	demonstrate	VERB
fnp-3050	101	5	that	that	SCONJ
fnp-3050	101	6	plaque	plaque	NOUN
fnp-3050	101	7	-	-	PUNCT
fnp-3050	101	8	associated	associate	VERB
fnp-3050	101	9	myeloid	myeloid	ADJ
fnp-3050	101	10	cells	cell	NOUN
fnp-3050	101	11	are	be	AUX
fnp-3050	101	12	derived	derive	VERB
fnp-3050	101	13	exclusively	exclusively	ADV
fnp-3050	101	14	from	from	ADP
fnp-3050	101	15	resident	resident	ADJ
fnp-3050	101	16	microglia	microglia	NOUN
fnp-3050	101	17	[	[	X
fnp-3050	101	18	67	67	NUM
fnp-3050	101	19	]	]	PUNCT
fnp-3050	101	20	.	.	PUNCT
fnp-3050	102	1	in	in	ADP
fnp-3050	102	2	ad	ad	NOUN
fnp-3050	102	3	,	,	PUNCT
fnp-3050	102	4	microglia	microglia	NOUN
fnp-3050	102	5	can	can	AUX
fnp-3050	102	6	eliminate	eliminate	VERB
fnp-3050	102	7	aps	ap	NOUN
fnp-3050	102	8	through	through	ADP
fnp-3050	102	9	phagocytosis	phagocytosis	NOUN
fnp-3050	102	10	with	with	ADP
fnp-3050	102	11	apoe	apoe	ADJ
fnp-3050	102	12	lipoprotein	lipoprotein	NOUN
fnp-3050	102	13	at	at	ADP
fnp-3050	102	14	an	an	DET
fnp-3050	102	15	early	early	ADJ
fnp-3050	102	16	stage	stage	NOUN
fnp-3050	102	17	of	of	ADP
fnp-3050	102	18	disease	disease	NOUN
fnp-3050	102	19	progression	progression	NOUN
fnp-3050	102	20	[	[	X
fnp-3050	102	21	68	68	NUM
fnp-3050	102	22	]	]	PUNCT
fnp-3050	102	23	.	.	PUNCT
fnp-3050	103	1	scanning	scan	VERB
fnp-3050	103	2	transmission	transmission	NOUN
fnp-3050	103	3	electron	electron	NOUN
fnp-3050	103	4	microscopy	microscopy	NOUN
fnp-3050	103	5	(	(	PUNCT
fnp-3050	103	6	stem	stem	NOUN
fnp-3050	103	7	)	)	PUNCT
fnp-3050	103	8	showed	show	VERB
fnp-3050	103	9	three	three	NUM
fnp-3050	103	10	types	type	NOUN
fnp-3050	103	11	of	of	ADP
fnp-3050	103	12	fibrillary	fibrillary	ADJ
fnp-3050	103	13	network	network	NOUN
fnp-3050	103	14	structures	structure	NOUN
fnp-3050	103	15	:	:	PUNCT
fnp-3050	103	16	amorphous	amorphous	ADJ
fnp-3050	103	17	network	network	NOUN
fnp-3050	103	18	,	,	PUNCT
fnp-3050	103	19	fibril	fibril	ADJ
fnp-3050	103	20	bundles	bundle	NOUN
fnp-3050	103	21	,	,	PUNCT
fnp-3050	103	22	and	and	CCONJ
fnp-3050	103	23	amyloid	amyloid	NOUN
fnp-3050	103	24	stars	star	NOUN
fnp-3050	104	1	[	[	X
fnp-3050	104	2	69	69	NUM
fnp-3050	104	3	]	]	PUNCT
fnp-3050	104	4	.	.	PUNCT
fnp-3050	105	1	although	although	SCONJ
fnp-3050	105	2	diffuse	diffuse	ADJ
fnp-3050	105	3	non	non	ADJ
fnp-3050	105	4	-	-	ADJ
fnp-3050	105	5	neuritic	neuritic	ADJ
fnp-3050	105	6	plaques	plaque	NOUN
fnp-3050	105	7	are	be	AUX
fnp-3050	105	8	generally	generally	ADV
fnp-3050	105	9	present	present	ADJ
fnp-3050	105	10	before	before	ADP
fnp-3050	105	11	nps	nps	PROPN
fnp-3050	105	12	,	,	PUNCT
fnp-3050	105	13	whether	whether	SCONJ
fnp-3050	105	14	an	an	DET
fnp-3050	105	15	individual	individual	ADJ
fnp-3050	105	16	diffuse	diffuse	NOUN
fnp-3050	105	17	plaque	plaque	NOUN
fnp-3050	105	18	can	can	AUX
fnp-3050	105	19	actually	actually	ADV
fnp-3050	105	20	transfer	transfer	VERB
fnp-3050	105	21	into	into	ADP
fnp-3050	105	22	an	an	DET
fnp-3050	105	23	np	np	NOUN
fnp-3050	105	24	or	or	CCONJ
fnp-3050	105	25	whether	whether	SCONJ
fnp-3050	105	26	these	these	DET
fnp-3050	105	27	two	two	NUM
fnp-3050	105	28	types	type	NOUN
fnp-3050	105	29	develop	develop	VERB
fnp-3050	105	30	differently	differently	ADV
fnp-3050	105	31	,	,	PUNCT
fnp-3050	105	32	is	be	AUX
fnp-3050	105	33	not	not	PART
fnp-3050	105	34	clear	clear	ADJ
fnp-3050	105	35	at	at	ADP
fnp-3050	105	36	present	present	ADJ
fnp-3050	105	37	.	.	PUNCT
fnp-3050	106	1	a	a	DET
fnp-3050	106	2	recently	recently	ADV
fnp-3050	106	3	described	describe	VERB
fnp-3050	106	4	type	type	NOUN
fnp-3050	106	5	called	call	VERB
fnp-3050	106	6	the	the	DET
fnp-3050	106	7	coarse	coarse	NOUN
fnp-3050	106	8	-	-	PUNCT
fnp-3050	106	9	grained	grain	VERB
fnp-3050	106	10	plaque	plaque	NOUN
fnp-3050	106	11	,	,	PUNCT
fnp-3050	106	12	a	a	DET
fnp-3050	106	13	relatively	relatively	ADV
fnp-3050	106	14	large	large	ADJ
fnp-3050	106	15	deposit	deposit	NOUN
fnp-3050	106	16	(	(	PUNCT
fnp-3050	106	17	diameter	diameter	NOUN
fnp-3050	106	18	about	about	ADV
fnp-3050	106	19	80	80	NUM
fnp-3050	106	20	µm	µm	NOUN
fnp-3050	106	21	)	)	PUNCT
fnp-3050	106	22	characterized	characterize	VERB
fnp-3050	106	23	by	by	ADP
fnp-3050	106	24	multiple	multiple	ADJ
fnp-3050	106	25	cores	core	NOUN
fnp-3050	106	26	and	and	CCONJ
fnp-3050	106	27	aβ	aβ	NOUN
fnp-3050	106	28	-	-	PUNCT
fnp-3050	106	29	devoid	devoid	ADJ
fnp-3050	106	30	pores	pore	NOUN
fnp-3050	106	31	,	,	PUNCT
fnp-3050	106	32	is	be	AUX
fnp-3050	106	33	prominent	prominent	ADJ
fnp-3050	106	34	in	in	ADP
fnp-3050	106	35	the	the	DET
fnp-3050	106	36	neocortex	neocortex	NOUN
fnp-3050	106	37	and	and	CCONJ
fnp-3050	106	38	associated	associate	VERB
fnp-3050	106	39	with	with	ADP
fnp-3050	106	40	homozygous	homozygous	ADJ
fnp-3050	106	41	apoeε4	apoeε4	NOUN
fnp-3050	106	42	status	status	NOUN
fnp-3050	106	43	and	and	CCONJ
fnp-3050	106	44	caa	caa	NOUN
fnp-3050	106	45	.	.	PUNCT
fnp-3050	107	1	this	this	DET
fnp-3050	107	2	divergent	divergent	ADJ
fnp-3050	107	3	ap	ap	PROPN
fnp-3050	107	4	type	type	NOUN
fnp-3050	107	5	is	be	AUX
fnp-3050	107	6	similar	similar	ADJ
fnp-3050	107	7	to	to	PART
fnp-3050	107	8	caa	caa	VERB
fnp-3050	107	9	,	,	PUNCT
fnp-3050	107	10	predominantly	predominantly	ADV
fnp-3050	107	11	composed	compose	VERB
fnp-3050	107	12	of	of	ADP
fnp-3050	107	13	aβ-40	aβ-40	PRON
fnp-3050	107	14	,	,	PUNCT
fnp-3050	107	15	and	and	CCONJ
fnp-3050	107	16	has	have	AUX
fnp-3050	107	17	been	be	AUX
fnp-3050	107	18	observed	observe	VERB
fnp-3050	107	19	particularly	particularly	ADV
fnp-3050	107	20	in	in	ADP
fnp-3050	107	21	early	early	ADJ
fnp-3050	107	22	-	-	PUNCT
fnp-3050	107	23	onset	onset	NOUN
fnp-3050	107	24	ad	ad	NOUN
fnp-3050	107	25	(	(	PUNCT
fnp-3050	107	26	eoad	eoad	NOUN
fnp-3050	107	27	)	)	PUNCT
fnp-3050	108	1	[	[	X
fnp-3050	108	2	70	70	NUM
fnp-3050	108	3	]	]	PUNCT
fnp-3050	108	4	.	.	PUNCT
fnp-3050	109	1	figure	figure	NOUN
fnp-3050	109	2	3	3	NUM
fnp-3050	109	3	.	.	PUNCT
fnp-3050	110	1	em	em	PRON
fnp-3050	110	2	image	image	NOUN
fnp-3050	110	3	of	of	ADP
fnp-3050	110	4	amyloid	amyloid	NOUN
fnp-3050	110	5	core	core	NOUN
fnp-3050	110	6	of	of	ADP
fnp-3050	110	7	a	a	DET
fnp-3050	110	8	neuritic	neuritic	ADJ
fnp-3050	110	9	plaque	plaque	NOUN
fnp-3050	110	10	.	.	PUNCT
fnp-3050	111	1	radiating	radiate	VERB
fnp-3050	111	2	bands	band	NOUN
fnp-3050	111	3	of	of	ADP
fnp-3050	111	4	amyloid	amyloid	NOUN
fnp-3050	111	5	fibrils	fibril	NOUN
fnp-3050	111	6	comprise	comprise	VERB
fnp-3050	111	7	the	the	DET
fnp-3050	111	8	core	core	NOUN
fnp-3050	111	9	(	(	PUNCT
fnp-3050	111	10	x	x	NOUN
fnp-3050	111	11	)	)	PUNCT
fnp-3050	111	12	.	.	PUNCT
fnp-3050	112	1	note	note	VERB
fnp-3050	112	2	the	the	DET
fnp-3050	112	3	adjacent	adjacent	ADJ
fnp-3050	112	4	abnormal	abnormal	ADJ
fnp-3050	112	5	fibrils	fibril	NOUN
fnp-3050	112	6	filled	fill	VERB
fnp-3050	112	7	with	with	ADP
fnp-3050	112	8	dense	dense	ADJ
fnp-3050	112	9	bodies	body	NOUN
fnp-3050	112	10	(	(	PUNCT
fnp-3050	112	11	arrows	arrow	NOUN
fnp-3050	112	12	)	)	PUNCT
fnp-3050	112	13	and	and	CCONJ
fnp-3050	112	14	surrounding	surround	VERB
fnp-3050	112	15	damaged	damage	VERB
fnp-3050	112	16	myelin	myelin	NOUN
fnp-3050	112	17	sheaths	sheath	NOUN
fnp-3050	112	18	(	(	PUNCT
fnp-3050	112	19	x	x	NOUN
fnp-3050	112	20	4000	4000	NUM
fnp-3050	112	21	)	)	PUNCT
fnp-3050	112	22	.	.	PUNCT
fnp-3050	113	1	“	"	PUNCT
fnp-3050	113	2	burnt	burn	VERB
fnp-3050	113	3	out	out	ADP
fnp-3050	113	4	”	"	PUNCT
fnp-3050	113	5	plaques	plaque	NOUN
fnp-3050	113	6	are	be	AUX
fnp-3050	113	7	composed	compose	VERB
fnp-3050	113	8	of	of	ADP
fnp-3050	113	9	dense	dense	ADJ
fnp-3050	113	10	cores	core	NOUN
fnp-3050	113	11	lacking	lack	VERB
fnp-3050	113	12	neuritic	neuritic	ADJ
fnp-3050	113	13	components	component	NOUN
fnp-3050	113	14	,	,	PUNCT
fnp-3050	113	15	while	while	SCONJ
fnp-3050	113	16	the	the	DET
fnp-3050	113	17	astrocytic	astrocytic	ADJ
fnp-3050	113	18	processes	process	NOUN
fnp-3050	113	19	penetrating	penetrate	VERB
fnp-3050	113	20	the	the	DET
fnp-3050	113	21	plaque	plaque	NOUN
fnp-3050	113	22	core	core	NOUN
fnp-3050	113	23	may	may	AUX
fnp-3050	113	24	represent	represent	VERB
fnp-3050	113	25	a	a	DET
fnp-3050	113	26	regressive	regressive	ADJ
fnp-3050	113	27	stage	stage	NOUN
fnp-3050	113	28	(	(	PUNCT
fnp-3050	113	29	“	"	PUNCT
fnp-3050	113	30	remnant	remnant	ADJ
fnp-3050	113	31	plaques	plaque	NOUN
fnp-3050	113	32	”	"	PUNCT
fnp-3050	113	33	)	)	PUNCT
fnp-3050	114	1	[	[	X
fnp-3050	114	2	72	72	NUM
fnp-3050	114	3	]	]	PUNCT
fnp-3050	114	4	.	.	PUNCT
fnp-3050	115	1	“	"	PUNCT
fnp-3050	115	2	cotton	cotton	NOUN
fnp-3050	115	3	wool	wool	NOUN
fnp-3050	115	4	plaques	plaque	NOUN
fnp-3050	115	5	”	"	PUNCT
fnp-3050	115	6	are	be	AUX
fnp-3050	115	7	non	non	ADJ
fnp-3050	115	8	-	-	ADJ
fnp-3050	115	9	compact	compact	ADJ
fnp-3050	115	10	deposits	deposit	NOUN
fnp-3050	115	11	,	,	PUNCT
fnp-3050	115	12	made	make	VERB
fnp-3050	115	13	of	of	ADP
fnp-3050	115	14	aβ-42	aβ-42	NOUN
fnp-3050	115	15	with	with	ADP
fnp-3050	115	16	sparse	sparse	ADJ
fnp-3050	115	17	glial	glial	ADJ
fnp-3050	115	18	components	component	NOUN
fnp-3050	115	19	and	and	CCONJ
fnp-3050	115	20	variable	variable	ADJ
fnp-3050	115	21	neurites	neurite	NOUN
fnp-3050	115	22	but	but	CCONJ
fnp-3050	115	23	not	not	PART
fnp-3050	115	24	surrounded	surround	VERB
fnp-3050	115	25	by	by	ADP
fnp-3050	115	26	a	a	DET
fnp-3050	115	27	neuritic	neuritic	ADJ
fnp-3050	115	28	corona	corona	NOUN
fnp-3050	115	29	.	.	PUNCT
fnp-3050	116	1	they	they	PRON
fnp-3050	116	2	can	can	AUX
fnp-3050	116	3	be	be	AUX
fnp-3050	116	4	detected	detect	VERB
fnp-3050	116	5	with	with	ADP
fnp-3050	116	6	h&e	h&e	PROPN
fnp-3050	116	7	staining	stain	VERB
fnp-3050	116	8	[	[	X
fnp-3050	116	9	61	61	NUM
fnp-3050	116	10	]	]	PUNCT
fnp-3050	116	11	.	.	PUNCT
fnp-3050	117	1	aβ	aβ	PRON
fnp-3050	117	2	and	and	CCONJ
fnp-3050	117	3	tau	tau	PROPN
fnp-3050	117	4	each	each	PRON
fnp-3050	117	5	begin	begin	VERB
fnp-3050	117	6	to	to	PART
fnp-3050	117	7	aggregate	aggregate	VERB
fnp-3050	117	8	in	in	ADP
fnp-3050	117	9	separate	separate	ADJ
fnp-3050	117	10	neuroanatomical	neuroanatomical	ADJ
fnp-3050	117	11	locations	location	NOUN
fnp-3050	117	12	and	and	CCONJ
fnp-3050	117	13	meet	meet	VERB
fnp-3050	117	14	in	in	ADP
fnp-3050	117	15	the	the	DET
fnp-3050	117	16	cerebral	cerebral	ADJ
fnp-3050	117	17	cortex	cortex	NOUN
fnp-3050	117	18	in	in	ADP
fnp-3050	117	19	the	the	DET
fnp-3050	117	20	np	np	NOUN
fnp-3050	117	21	.	.	PUNCT
fnp-3050	118	1	this	this	DET
fnp-3050	118	2	“	"	PUNCT
fnp-3050	118	3	collision	collision	NOUN
fnp-3050	118	4	”	"	PUNCT
fnp-3050	118	5	of	of	ADP
fnp-3050	118	6	both	both	DET
fnp-3050	118	7	proteins	protein	NOUN
fnp-3050	118	8	mediated	mediate	VERB
fnp-3050	118	9	by	by	ADP
fnp-3050	118	10	microglia	microglia	NOUN
fnp-3050	118	11	has	have	VERB
fnp-3050	118	12	devastating	devastating	ADJ
fnp-3050	118	13	consequences	consequence	NOUN
fnp-3050	118	14	in	in	ADP
fnp-3050	118	15	terms	term	NOUN
fnp-3050	118	16	of	of	ADP
fnp-3050	118	17	neuronal	neuronal	ADJ
fnp-3050	118	18	loss	loss	NOUN
fnp-3050	118	19	,	,	PUNCT
fnp-3050	118	20	promoting	promote	VERB
fnp-3050	118	21	neurodegeneration	neurodegeneration	NOUN
fnp-3050	118	22	and	and	CCONJ
fnp-3050	118	23	the	the	DET
fnp-3050	118	24	consequent	consequent	ADJ
fnp-3050	118	25	development	development	NOUN
fnp-3050	118	26	of	of	ADP
fnp-3050	118	27	cognitive	cognitive	ADJ
fnp-3050	118	28	decline	decline	NOUN
fnp-3050	118	29	,	,	PUNCT
fnp-3050	118	30	but	but	CCONJ
fnp-3050	118	31	this	this	PRON
fnp-3050	118	32	is	be	AUX
fnp-3050	118	33	still	still	ADV
fnp-3050	118	34	under	under	ADP
fnp-3050	118	35	investigation	investigation	NOUN
fnp-3050	118	36	[	[	X
fnp-3050	118	37	73	73	NUM
fnp-3050	118	38	]	]	PUNCT
fnp-3050	118	39	.	.	PUNCT
fnp-3050	119	1	2.4	2.4	NUM
fnp-3050	119	2	.	.	PUNCT
fnp-3050	120	1	distribution	distribution	NOUN
fnp-3050	120	2	of	of	ADP
fnp-3050	120	3	amyloid	amyloid	NOUN
fnp-3050	120	4	deposits	deposit	VERB
fnp-3050	120	5	aps	ap	NOUN
fnp-3050	120	6	in	in	ADP
fnp-3050	120	7	ad	ad	NOUN
fnp-3050	120	8	brain	brain	NOUN
fnp-3050	120	9	show	show	VERB
fnp-3050	120	10	a	a	DET
fnp-3050	120	11	typical	typical	ADJ
fnp-3050	120	12	distribution	distribution	NOUN
fnp-3050	120	13	with	with	ADP
fnp-3050	120	14	brain	brain	NOUN
fnp-3050	120	15	areas	area	NOUN
fnp-3050	120	16	that	that	PRON
fnp-3050	120	17	are	be	AUX
fnp-3050	120	18	connected	connect	VERB
fnp-3050	120	19	via	via	ADP
fnp-3050	120	20	the	the	DET
fnp-3050	120	21	“	"	PUNCT
fnp-3050	120	22	default	default	NOUN
fnp-3050	120	23	network	network	NOUN
fnp-3050	120	24	”	"	PUNCT
fnp-3050	120	25	typically	typically	ADV
fnp-3050	120	26	affected	affect	VERB
fnp-3050	120	27	early	early	ADV
fnp-3050	120	28	.	.	PUNCT
fnp-3050	121	1	in	in	ADP
fnp-3050	121	2	animal	animal	NOUN
fnp-3050	121	3	models	model	NOUN
fnp-3050	121	4	some	some	DET
fnp-3050	121	5	demonstration	demonstration	NOUN
fnp-3050	121	6	of	of	ADP
fnp-3050	121	7	“	"	PUNCT
fnp-3050	121	8	propagation	propagation	NOUN
fnp-3050	121	9	”	"	PUNCT
fnp-3050	121	10	along	along	ADP
fnp-3050	121	11	neuronal	neuronal	ADJ
fnp-3050	121	12	systems	system	NOUN
fnp-3050	121	13	has	have	AUX
fnp-3050	121	14	been	be	AUX
fnp-3050	121	15	observed	observe	VERB
fnp-3050	121	16	[	[	X
fnp-3050	121	17	74	74	NUM
fnp-3050	121	18	,	,	PUNCT
fnp-3050	121	19	75	75	NUM
fnp-3050	121	20	]	]	PUNCT
fnp-3050	121	21	,	,	PUNCT
fnp-3050	121	22	suggesting	suggest	VERB
fnp-3050	121	23	some	some	DET
fnp-3050	121	24	axonal	axonal	ADJ
fnp-3050	121	25	transport	transport	NOUN
fnp-3050	121	26	of	of	ADP
fnp-3050	121	27	seeds	seed	NOUN
fnp-3050	121	28	that	that	PRON
fnp-3050	121	29	lead	lead	VERB
fnp-3050	121	30	to	to	ADP
fnp-3050	121	31	extracellular	extracellular	ADJ
fnp-3050	121	32	deposits	deposit	NOUN
fnp-3050	121	33	.	.	PUNCT
fnp-3050	122	1	most	most	ADJ
fnp-3050	122	2	aβ	aβ	PRON
fnp-3050	122	3	deposits	deposit	NOUN
fnp-3050	122	4	are	be	AUX
fnp-3050	122	5	located	locate	VERB
fnp-3050	122	6	in	in	ADP
fnp-3050	122	7	the	the	DET
fnp-3050	122	8	gray	gray	ADJ
fnp-3050	122	9	matter	matter	NOUN
fnp-3050	122	10	,	,	PUNCT
fnp-3050	122	11	while	while	SCONJ
fnp-3050	122	12	some	some	DET
fnp-3050	122	13	diffuse	diffuse	NOUN
fnp-3050	122	14	or	or	CCONJ
fnp-3050	122	15	lake	lake	NOUN
fnp-3050	122	16	-	-	PUNCT
fnp-3050	122	17	like	like	ADJ
fnp-3050	122	18	deposits	deposit	NOUN
fnp-3050	122	19	may	may	AUX
fnp-3050	122	20	be	be	AUX
fnp-3050	122	21	seen	see	VERB
fnp-3050	122	22	in	in	ADP
fnp-3050	122	23	the	the	DET
fnp-3050	122	24	subpial	subpial	ADJ
fnp-3050	122	25	white	white	ADJ
fnp-3050	122	26	matter	matter	NOUN
fnp-3050	122	27	.	.	PUNCT
fnp-3050	123	1	cortical	cortical	ADJ
fnp-3050	123	2	soluble	soluble	ADJ
fnp-3050	123	3	aβ	aβ	NOUN
fnp-3050	123	4	protein	protein	NOUN
fnp-3050	123	5	is	be	AUX
fnp-3050	123	6	a	a	DET
fnp-3050	123	7	neurotoxic	neurotoxic	ADJ
fnp-3050	123	8	agent	agent	NOUN
fnp-3050	123	9	[	[	X
fnp-3050	123	10	76	76	NUM
fnp-3050	123	11	,	,	PUNCT
fnp-3050	123	12	77	77	NUM
fnp-3050	123	13	]	]	PUNCT
fnp-3050	123	14	,	,	PUNCT
fnp-3050	123	15	and	and	CCONJ
fnp-3050	123	16	aβ	aβ	PRON
fnp-3050	123	17	oligomers	oligomer	NOUN
fnp-3050	123	18	(	(	PUNCT
fnp-3050	123	19	aβos	aβos	PROPN
fnp-3050	123	20	)	)	PUNCT
fnp-3050	123	21	may	may	AUX
fnp-3050	123	22	trigger	trigger	VERB
fnp-3050	123	23	the	the	DET
fnp-3050	123	24	early	early	ADJ
fnp-3050	123	25	phase	phase	NOUN
fnp-3050	123	26	of	of	ADP
fnp-3050	123	27	the	the	DET
fnp-3050	123	28	aβ	aβ	NOUN
fnp-3050	123	29	seeding	seeding	NOUN
fnp-3050	123	30	process	process	NOUN
fnp-3050	123	31	,	,	PUNCT
fnp-3050	123	32	while	while	SCONJ
fnp-3050	123	33	depletion	depletion	NOUN
fnp-3050	123	34	of	of	ADP
fnp-3050	123	35	aβos	aβos	PROPN
fnp-3050	123	36	delays	delay	VERB
fnp-3050	123	37	the	the	DET
fnp-3050	123	38	aggregation	aggregation	NOUN
fnp-3050	123	39	process	process	NOUN
fnp-3050	123	40	leading	lead	VERB
fnp-3050	123	41	to	to	ADP
fnp-3050	123	42	a	a	DET
fnp-3050	123	43	transient	transient	ADJ
fnp-3050	123	44	reduction	reduction	NOUN
fnp-3050	123	45	of	of	ADP
fnp-3050	123	46	seed	seed	NOUN
fnp-3050	123	47	-	-	PUNCT
fnp-3050	123	48	induced	induce	VERB
fnp-3050	123	49	aβ	aβ	NUM
fnp-3050	123	50	deposits	deposit	NOUN
fnp-3050	123	51	[	[	X
fnp-3050	123	52	78	78	NUM
fnp-3050	123	53	]	]	PUNCT
fnp-3050	123	54	.	.	PUNCT
fnp-3050	124	1	the	the	DET
fnp-3050	124	2	topography	topography	NOUN
fnp-3050	124	3	of	of	ADP
fnp-3050	124	4	aβ	aβ	PRON
fnp-3050	124	5	deposits	deposit	NOUN
fnp-3050	124	6	depends	depend	VERB
fnp-3050	124	7	on	on	ADP
fnp-3050	124	8	the	the	DET
fnp-3050	124	9	stage	stage	NOUN
fnp-3050	124	10	of	of	ADP
fnp-3050	124	11	the	the	DET
fnp-3050	124	12	disease	disease	NOUN
fnp-3050	124	13	,	,	PUNCT
fnp-3050	124	14	which	which	PRON
fnp-3050	124	15	leaded	lead	VERB
fnp-3050	124	16	to	to	ADP
fnp-3050	124	17	several	several	ADJ
fnp-3050	124	18	staging	staging	NOUN
fnp-3050	124	19	schemes	scheme	NOUN
fnp-3050	124	20	.	.	PUNCT
fnp-3050	125	1	three	three	NUM
fnp-3050	125	2	stages	stage	NOUN
fnp-3050	125	3	were	be	AUX
fnp-3050	125	4	distinguished	distinguish	VERB
fnp-3050	125	5	:	:	PUNCT
fnp-3050	125	6	stage	stage	VERB
fnp-3050	125	7	a	a	PRON
fnp-3050	125	8	with	with	ADP
fnp-3050	125	9	amyloid	amyloid	NOUN
fnp-3050	125	10	deposits	deposit	NOUN
fnp-3050	125	11	in	in	ADP
fnp-3050	125	12	the	the	DET
fnp-3050	125	13	basal	basal	ADJ
fnp-3050	125	14	portions	portion	NOUN
fnp-3050	125	15	of	of	ADP
fnp-3050	125	16	the	the	DET
fnp-3050	125	17	frontal	frontal	ADJ
fnp-3050	125	18	,	,	PUNCT
fnp-3050	125	19	temporal	temporal	ADJ
fnp-3050	125	20	and	and	CCONJ
fnp-3050	125	21	occipital	occipital	ADJ
fnp-3050	125	22	cortex	cortex	NOUN
fnp-3050	125	23	;	;	PUNCT
fnp-3050	125	24	in	in	ADP
fnp-3050	125	25	stage	stage	NOUN
fnp-3050	125	26	b	b	PRON
fnp-3050	125	27	all	all	DET
fnp-3050	125	28	isocortex	isocortex	NOUN
fnp-3050	125	29	is	be	AUX
fnp-3050	125	30	involved	involve	VERB
fnp-3050	125	31	,	,	PUNCT
fnp-3050	125	32	with	with	SCONJ
fnp-3050	125	33	primary	primary	ADJ
fnp-3050	125	34	cortices	cortex	NOUN
fnp-3050	125	35	spared	spare	VERB
fnp-3050	125	36	and	and	CCONJ
fnp-3050	125	37	the	the	DET
fnp-3050	125	38	hippocampus	hippocampus	NOUN
fnp-3050	125	39	only	only	ADV
fnp-3050	125	40	mildly	mildly	ADV
fnp-3050	125	41	affected	affect	VERB
fnp-3050	125	42	;	;	PUNCT
fnp-3050	125	43	while	while	SCONJ
fnp-3050	125	44	stage	stage	NOUN
fnp-3050	125	45	c	c	PROPN
fnp-3050	125	46	shows	show	VERB
fnp-3050	125	47	deposits	deposit	NOUN
fnp-3050	125	48	in	in	ADP
fnp-3050	125	49	the	the	DET
fnp-3050	125	50	whole	whole	ADJ
fnp-3050	125	51	isocortex	isocortex	NOUN
fnp-3050	125	52	including	include	VERB
fnp-3050	125	53	sensory	sensory	ADJ
fnp-3050	125	54	and	and	CCONJ
fnp-3050	125	55	motor	motor	NOUN
fnp-3050	125	56	core	core	NOUN
fnp-3050	125	57	fields	field	NOUN
fnp-3050	125	58	[	[	X
fnp-3050	125	59	18	18	NUM
fnp-3050	125	60	]	]	PUNCT
fnp-3050	125	61	.	.	PUNCT
fnp-3050	126	1	others	other	NOUN
fnp-3050	126	2	proposed	propose	VERB
fnp-3050	126	3	five	five	NUM
fnp-3050	126	4	amyloid	amyloid	NOUN
fnp-3050	126	5	“	"	PUNCT
fnp-3050	126	6	phases	phase	NOUN
fnp-3050	126	7	”	"	PUNCT
fnp-3050	126	8	using	use	VERB
fnp-3050	126	9	sensitive	sensitive	ADJ
fnp-3050	126	10	silver	silver	NOUN
fnp-3050	126	11	staining	stain	VERB
fnp-3050	126	12	or	or	CCONJ
fnp-3050	126	13	aβ	aβ	PRON
fnp-3050	126	14	antibodies	antibodie	VERB
fnp-3050	126	15	:	:	PUNCT
fnp-3050	126	16	stage	stage	NOUN
fnp-3050	126	17	1	1	NUM
fnp-3050	126	18	or	or	CCONJ
fnp-3050	126	19	isocortical	isocortical	ADJ
fnp-3050	126	20	,	,	PUNCT
fnp-3050	126	21	stage	stage	NOUN
fnp-3050	126	22	2	2	NUM
fnp-3050	126	23	with	with	ADP
fnp-3050	126	24	additional	additional	ADJ
fnp-3050	126	25	involvement	involvement	NOUN
fnp-3050	126	26	of	of	ADP
fnp-3050	126	27	hippocampus	hippocampus	NOUN
fnp-3050	126	28	and	and	CCONJ
fnp-3050	126	29	entorhinal	entorhinal	ADJ
fnp-3050	126	30	cortex	cortex	NOUN
fnp-3050	126	31	,	,	PUNCT
fnp-3050	126	32	stage	stage	NOUN
fnp-3050	126	33	3	3	NUM
fnp-3050	126	34	plus	plus	CCONJ
fnp-3050	126	35	striatum	striatum	NOUN
fnp-3050	126	36	and	and	CCONJ
fnp-3050	126	37	diencephalic	diencephalic	ADJ
fnp-3050	126	38	nuclei	nucleus	NOUN
fnp-3050	126	39	,	,	PUNCT
fnp-3050	126	40	stage	stage	VERB
fnp-3050	126	41	4	4	NUM
fnp-3050	126	42	several	several	ADJ
fnp-3050	126	43	brainstem	brainstem	NOUN
fnp-3050	126	44	nuclei	nucleus	NOUN
fnp-3050	126	45	and	and	CCONJ
fnp-3050	126	46	medulla	medulla	NOUN
fnp-3050	126	47	oblongata	oblongata	NOUN
fnp-3050	126	48	,	,	PUNCT
fnp-3050	126	49	and	and	CCONJ
fnp-3050	126	50	stage	stage	NOUN
fnp-3050	126	51	5	5	NUM
fnp-3050	126	52	presenting	present	VERB
fnp-3050	126	53	amyloid	amyloid	NOUN
fnp-3050	126	54	deposits	deposit	NOUN
fnp-3050	126	55	in	in	ADP
fnp-3050	126	56	the	the	DET
fnp-3050	126	57	pons	pon	NOUN
fnp-3050	126	58	and	and	CCONJ
fnp-3050	126	59	molecular	molecular	ADJ
fnp-3050	126	60	layer	layer	NOUN
fnp-3050	126	61	of	of	ADP
fnp-3050	126	62	the	the	DET
fnp-3050	126	63	cerebellum	cerebellum	NOUN
fnp-3050	126	64	[	[	X
fnp-3050	126	65	79	79	NUM
fnp-3050	126	66	,	,	PUNCT
fnp-3050	126	67	80	80	NUM
fnp-3050	126	68	]	]	PUNCT
fnp-3050	126	69	.	.	PUNCT
fnp-3050	127	1	these	these	PRON
fnp-3050	127	2	can	can	AUX
fnp-3050	127	3	be	be	AUX
fnp-3050	127	4	reduced	reduce	VERB
fnp-3050	127	5	to	to	ADP
fnp-3050	127	6	three	three	NUM
fnp-3050	127	7	stages	stage	NOUN
fnp-3050	127	8	:	:	PUNCT
fnp-3050	127	9	1	1	NUM
fnp-3050	127	10	isocortical	isocortical	ADJ
fnp-3050	127	11	,	,	PUNCT
fnp-3050	127	12	2	2	NUM
fnp-3050	127	13	allocortical	allocortical	ADJ
fnp-3050	127	14	or	or	CCONJ
fnp-3050	127	15	limbic	limbic	ADJ
fnp-3050	127	16	,	,	PUNCT
fnp-3050	127	17	and	and	CCONJ
fnp-3050	127	18	3	3	NUM
fnp-3050	127	19	subcortical	subcortical	NOUN
fnp-3050	127	20	.	.	PUNCT
fnp-3050	128	1	usually	usually	ADV
fnp-3050	128	2	involved	involve	VERB
fnp-3050	128	3	is	be	AUX
fnp-3050	128	4	the	the	DET
fnp-3050	128	5	total	total	ADJ
fnp-3050	128	6	isocortex	isocortex	NOUN
fnp-3050	128	7	,	,	PUNCT
fnp-3050	128	8	layers	layers	PROPN
fnp-3050	128	9	ii	ii	PROPN
fnp-3050	128	10	-	-	PUNCT
fnp-3050	128	11	v	v	NOUN
fnp-3050	128	12	more	more	ADJ
fnp-3050	128	13	than	than	ADP
fnp-3050	128	14	layers	layer	NOUN
fnp-3050	128	15	i	i	PRON
fnp-3050	128	16	and	and	CCONJ
fnp-3050	128	17	vi	vi	X
fnp-3050	129	1	[	[	X
fnp-3050	129	2	18	18	NUM
fnp-3050	129	3	]	]	PUNCT
fnp-3050	129	4	.	.	PUNCT
fnp-3050	130	1	in	in	ADP
fnp-3050	130	2	advanced	advanced	ADJ
fnp-3050	130	3	cases	case	NOUN
fnp-3050	130	4	band	band	NOUN
fnp-3050	130	5	-	-	PUNCT
fnp-3050	130	6	like	like	ADJ
fnp-3050	130	7	diffuse	diffuse	NOUN
fnp-3050	130	8	aβ	aβ	NOUN
fnp-3050	130	9	deposits	deposit	NOUN
fnp-3050	130	10	are	be	AUX
fnp-3050	130	11	also	also	ADV
fnp-3050	130	12	seen	see	VERB
fnp-3050	130	13	in	in	ADP
fnp-3050	130	14	the	the	DET
fnp-3050	130	15	subpial	subpial	ADJ
fnp-3050	130	16	surface	surface	NOUN
fnp-3050	130	17	of	of	ADP
fnp-3050	130	18	the	the	DET
fnp-3050	130	19	cortex	cortex	NOUN
fnp-3050	130	20	or	or	CCONJ
fnp-3050	130	21	in	in	ADP
fnp-3050	130	22	the	the	DET
fnp-3050	130	23	white	white	ADJ
fnp-3050	130	24	matter	matter	NOUN
fnp-3050	130	25	close	close	ADV
fnp-3050	130	26	to	to	ADP
fnp-3050	130	27	layer	layer	NOUN
fnp-3050	130	28	vi	vi	NOUN
fnp-3050	131	1	[	[	X
fnp-3050	131	2	71	71	NUM
fnp-3050	131	3	]	]	PUNCT
fnp-3050	131	4	.	.	PUNCT
fnp-3050	132	1	amyloid	amyloid	PROPN
fnp-3050	132	2	pet	pet	NOUN
fnp-3050	132	3	-	-	PUNCT
fnp-3050	132	4	based	base	VERB
fnp-3050	132	5	staging	staging	NOUN
fnp-3050	132	6	of	of	ADP
fnp-3050	132	7	aβ	aβ	DET
fnp-3050	132	8	pathology	pathology	NOUN
fnp-3050	132	9	in	in	ADP
fnp-3050	132	10	vivo	vivo	NOUN
fnp-3050	132	11	confirmed	confirm	VERB
fnp-3050	132	12	its	its	PRON
fnp-3050	132	13	progression	progression	NOUN
fnp-3050	132	14	in	in	ADP
fnp-3050	132	15	ad	ad	NOUN
fnp-3050	132	16	[	[	X
fnp-3050	132	17	81	81	NUM
fnp-3050	132	18	]	]	PUNCT
fnp-3050	132	19	,	,	PUNCT
fnp-3050	132	20	and	and	CCONJ
fnp-3050	132	21	revealed	reveal	VERB
fnp-3050	132	22	higher	high	ADJ
fnp-3050	132	23	plaque	plaque	NOUN
fnp-3050	132	24	counts	count	NOUN
fnp-3050	132	25	in	in	ADP
fnp-3050	132	26	entorhinal	entorhinal	ADJ
fnp-3050	132	27	and	and	CCONJ
fnp-3050	132	28	occipital	occipital	ADJ
fnp-3050	132	29	regions	region	NOUN
fnp-3050	132	30	of	of	ADP
fnp-3050	132	31	typical	typical	ADJ
fnp-3050	132	32	ad	ad	NOUN
fnp-3050	132	33	,	,	PUNCT
fnp-3050	132	34	while	while	SCONJ
fnp-3050	132	35	other	other	ADJ
fnp-3050	132	36	phenotypes	phenotype	NOUN
fnp-3050	132	37	showed	show	VERB
fnp-3050	132	38	more	more	ADV
fnp-3050	132	39	severe	severe	ADJ
fnp-3050	132	40	aβ	aβ	NOUN
fnp-3050	132	41	deposition	deposition	NOUN
fnp-3050	132	42	in	in	ADP
fnp-3050	132	43	frontal	frontal	ADJ
fnp-3050	132	44	and	and	CCONJ
fnp-3050	132	45	parietal	parietal	ADJ
fnp-3050	132	46	cortices	cortex	NOUN
fnp-3050	132	47	[	[	X
fnp-3050	132	48	82	82	NUM
fnp-3050	132	49	]	]	PUNCT
fnp-3050	132	50	.	.	PUNCT
fnp-3050	133	1	post	post	ADJ
fnp-3050	133	2	-	-	ADJ
fnp-3050	133	3	mortem	mortem	ADJ
fnp-3050	133	4	analysis	analysis	NOUN
fnp-3050	133	5	of	of	ADP
fnp-3050	133	6	(	(	PUNCT
fnp-3050	133	7	18)fflutemetamol	18)fflutemetamol	NUM
fnp-3050	133	8	and	and	CCONJ
fnp-3050	133	9	(	(	PUNCT
fnp-3050	133	10	11)cpib	11)cpib	PROPN
fnp-3050	133	11	pet	pet	ADJ
fnp-3050	133	12	signal	signal	NOUN
fnp-3050	133	13	showed	show	VERB
fnp-3050	133	14	that	that	SCONJ
fnp-3050	133	15	it	it	PRON
fnp-3050	133	16	is	be	AUX
fnp-3050	133	17	influenced	influence	VERB
fnp-3050	133	18	by	by	ADP
fnp-3050	133	19	both	both	DET
fnp-3050	133	20	diffuse	diffuse	ADJ
fnp-3050	133	21	plaques	plaque	NOUN
fnp-3050	133	22	and	and	CCONJ
fnp-3050	133	23	cored	core	VERB
fnp-3050	133	24	plaques	plaque	NOUN
fnp-3050	133	25	and	and	CCONJ
fnp-3050	133	26	,	,	PUNCT
fnp-3050	133	27	therefore	therefore	ADV
fnp-3050	133	28	,	,	PUNCT
fnp-3050	133	29	is	be	AUX
fnp-3050	133	30	likely	likely	ADJ
fnp-3050	133	31	a	a	DET
fnp-3050	133	32	function	function	NOUN
fnp-3050	133	33	of	of	ADP
fnp-3050	133	34	plaque	plaque	NOUN
fnp-3050	133	35	size	size	NOUN
fnp-3050	133	36	and	and	CCONJ
fnp-3050	133	37	density	density	NOUN
fnp-3050	133	38	of	of	ADP
fnp-3050	133	39	aβ	aβ	NOUN
fnp-3050	133	40	fibrils	fibril	NOUN
fnp-3050	133	41	in	in	ADP
fnp-3050	133	42	plaques	plaque	NOUN
fnp-3050	133	43	.	.	PUNCT
fnp-3050	134	1	brain	brain	NOUN
fnp-3050	134	2	regions	region	NOUN
fnp-3050	134	3	with	with	ADP
fnp-3050	134	4	large	large	ADJ
fnp-3050	134	5	volumes	volume	NOUN
fnp-3050	134	6	of	of	ADP
fnp-3050	134	7	diffuse	diffuse	ADJ
fnp-3050	134	8	plaques	plaque	NOUN
fnp-3050	134	9	could	could	AUX
fnp-3050	134	10	yield	yield	VERB
fnp-3050	134	11	pet	pet	ADJ
fnp-3050	134	12	retention	retention	NOUN
fnp-3050	134	13	levels	level	NOUN
fnp-3050	134	14	comparable	comparable	ADJ
fnp-3050	134	15	with	with	ADP
fnp-3050	134	16	lower	low	ADJ
fnp-3050	134	17	volume	volume	NOUN
fnp-3050	134	18	/	/	SYM
fnp-3050	134	19	frequency	frequency	NOUN
fnp-3050	134	20	of	of	ADP
fnp-3050	134	21	cored	core	VERB
fnp-3050	134	22	plaques	plaque	NOUN
fnp-3050	134	23	[	[	X
fnp-3050	134	24	83	83	NUM
fnp-3050	134	25	]	]	PUNCT
fnp-3050	134	26	.	.	PUNCT
fnp-3050	135	1	2.5	2.5	NUM
fnp-3050	135	2	.	.	PUNCT
fnp-3050	136	1	cerebral	cerebral	ADJ
fnp-3050	136	2	amyloid	amyloid	NOUN
fnp-3050	136	3	angiopathy	angiopathy	ADJ
fnp-3050	136	4	aβ	aβ	PRON
fnp-3050	136	5	peptides	peptide	NOUN
fnp-3050	136	6	also	also	ADV
fnp-3050	136	7	involve	involve	VERB
fnp-3050	136	8	the	the	DET
fnp-3050	136	9	vessel	vessel	NOUN
fnp-3050	136	10	walls	wall	NOUN
fnp-3050	136	11	,	,	PUNCT
fnp-3050	136	12	as	as	ADP
fnp-3050	136	13	with	with	ADP
fnp-3050	136	14	caa	caa	NOUN
fnp-3050	136	15	,	,	PUNCT
fnp-3050	136	16	with	with	ADP
fnp-3050	136	17	the	the	DET
fnp-3050	136	18	more	more	ADV
fnp-3050	136	19	soluble	soluble	ADJ
fnp-3050	136	20	aβ-40	aβ-40	NOUN
fnp-3050	136	21	as	as	ADP
fnp-3050	136	22	the	the	DET
fnp-3050	136	23	major	major	ADJ
fnp-3050	136	24	constituent	constituent	NOUN
fnp-3050	136	25	.	.	PUNCT
fnp-3050	137	1	85	85	NUM
fnp-3050	137	2	-	-	SYM
fnp-3050	137	3	90	90	NUM
fnp-3050	137	4	%	%	NOUN
fnp-3050	137	5	of	of	ADP
fnp-3050	137	6	confirmed	confirm	VERB
fnp-3050	137	7	ad	ad	NOUN
fnp-3050	137	8	cases	case	NOUN
fnp-3050	137	9	have	have	VERB
fnp-3050	137	10	some	some	DET
fnp-3050	137	11	degree	degree	NOUN
fnp-3050	137	12	of	of	ADP
fnp-3050	137	13	caa	caa	NOUN
fnp-3050	137	14	[	[	X
fnp-3050	137	15	84	84	NUM
fnp-3050	137	16	]	]	PUNCT
fnp-3050	137	17	.	.	PUNCT
fnp-3050	138	1	it	it	PRON
fnp-3050	138	2	mainly	mainly	ADV
fnp-3050	138	3	accumulates	accumulate	VERB
fnp-3050	138	4	in	in	ADP
fnp-3050	138	5	the	the	DET
fnp-3050	138	6	interstitium	interstitium	NOUN
fnp-3050	138	7	between	between	ADP
fnp-3050	138	8	the	the	DET
fnp-3050	138	9	smooth	smooth	ADJ
fnp-3050	138	10	cells	cell	NOUN
fnp-3050	138	11	of	of	ADP
fnp-3050	138	12	the	the	DET
fnp-3050	138	13	tunica	tunica	PROPN
fnp-3050	138	14	media	medium	NOUN
fnp-3050	138	15	.	.	PUNCT
fnp-3050	139	1	small	small	ADJ
fnp-3050	139	2	arteries	artery	NOUN
fnp-3050	139	3	,	,	PUNCT
fnp-3050	139	4	arterioles	arteriole	NOUN
fnp-3050	139	5	and	and	CCONJ
fnp-3050	139	6	even	even	ADV
fnp-3050	139	7	capillaries	capillary	NOUN
fnp-3050	139	8	in	in	ADP
fnp-3050	139	9	the	the	DET
fnp-3050	139	10	cerebral	cerebral	ADJ
fnp-3050	139	11	cortex	cortex	NOUN
fnp-3050	139	12	and	and	CCONJ
fnp-3050	139	13	leptomeningeal	leptomeningeal	NOUN
fnp-3050	139	14	vessels	vessel	NOUN
fnp-3050	139	15	are	be	AUX
fnp-3050	139	16	affected	affect	VERB
fnp-3050	139	17	[	[	PUNCT
fnp-3050	139	18	85	85	NUM
fnp-3050	139	19	]	]	PUNCT
fnp-3050	139	20	.	.	PUNCT
fnp-3050	140	1	stage	stage	NOUN
fnp-3050	140	2	1	1	NUM
fnp-3050	140	3	:	:	PUNCT
fnp-3050	140	4	vessels	vessel	NOUN
fnp-3050	140	5	are	be	AUX
fnp-3050	140	6	affected	affect	VERB
fnp-3050	140	7	in	in	ADP
fnp-3050	140	8	the	the	DET
fnp-3050	140	9	isocortex	isocortex	NOUN
fnp-3050	140	10	,	,	PUNCT
fnp-3050	140	11	stage	stage	NOUN
fnp-3050	140	12	2	2	NUM
fnp-3050	140	13	:	:	PUNCT
fnp-3050	140	14	involvement	involvement	NOUN
fnp-3050	140	15	of	of	ADP
fnp-3050	140	16	allocortex	allocortex	NOUN
fnp-3050	140	17	,	,	PUNCT
fnp-3050	140	18	and	and	CCONJ
fnp-3050	140	19	stage	stage	NOUN
fnp-3050	140	20	3	3	NUM
fnp-3050	140	21	:	:	PUNCT
fnp-3050	140	22	basal	basal	ADJ
fnp-3050	140	23	ganglia	ganglia	NOUN
fnp-3050	140	24	,	,	PUNCT
fnp-3050	140	25	thalamus	thalamus	NOUN
fnp-3050	140	26	,	,	PUNCT
fnp-3050	140	27	pons	pon	NOUN
fnp-3050	140	28	and	and	CCONJ
fnp-3050	140	29	medulla	medulla	NOUN
fnp-3050	140	30	oblongata	oblongata	NOUN
fnp-3050	141	1	[	[	X
fnp-3050	141	2	86	86	NUM
fnp-3050	141	3	]	]	PUNCT
fnp-3050	141	4	.	.	PUNCT
fnp-3050	142	1	others	other	NOUN
fnp-3050	142	2	distinguished	distinguish	VERB
fnp-3050	142	3	four	four	NUM
fnp-3050	142	4	patterns	pattern	NOUN
fnp-3050	142	5	[	[	X
fnp-3050	142	6	87	87	NUM
fnp-3050	142	7	]	]	SYM
fnp-3050	142	8	:	:	PUNCT
fnp-3050	142	9	type	type	NOUN
fnp-3050	142	10	1	1	NUM
fnp-3050	142	11	:	:	PUNCT
fnp-3050	142	12	aps	ap	NOUN
fnp-3050	142	13	with	with	ADP
fnp-3050	142	14	or	or	CCONJ
fnp-3050	142	15	without	without	ADP
fnp-3050	142	16	caa	caa	NOUN
fnp-3050	142	17	in	in	ADP
fnp-3050	142	18	the	the	DET
fnp-3050	142	19	leptomeninges	leptomeninge	NOUN
fnp-3050	142	20	alone	alone	ADV
fnp-3050	142	21	;	;	PUNCT
fnp-3050	142	22	type	type	NOUN
fnp-3050	142	23	2	2	NUM
fnp-3050	142	24	:	:	PUNCT
fnp-3050	142	25	caa	caa	NOUN
fnp-3050	142	26	in	in	ADP
fnp-3050	142	27	both	both	CCONJ
fnp-3050	142	28	leptomeningeal	leptomeningeal	ADJ
fnp-3050	142	29	and	and	CCONJ
fnp-3050	142	30	deeper	deep	ADJ
fnp-3050	142	31	penetrating	penetrate	VERB
fnp-3050	142	32	arteries	artery	NOUN
fnp-3050	142	33	(	(	PUNCT
fnp-3050	142	34	fig	fig	NOUN
fnp-3050	142	35	1a	1a	NOUN
fnp-3050	142	36	)	)	PUNCT
fnp-3050	142	37	;	;	PUNCT
fnp-3050	142	38	type	type	NOUN
fnp-3050	142	39	3	3	NUM
fnp-3050	142	40	:	:	PUNCT
fnp-3050	142	41	caa	caa	NOUN
fnp-3050	142	42	affects	affect	VERB
fnp-3050	142	43	both	both	DET
fnp-3050	142	44	precapillaries	precapillarie	NOUN
fnp-3050	142	45	and	and	CCONJ
fnp-3050	142	46	arterioles	arterioles	PROPN
fnp-3050	142	47	;	;	PUNCT
fnp-3050	142	48	type	type	NOUN
fnp-3050	142	49	4	4	NUM
fnp-3050	142	50	shows	show	VERB
fnp-3050	142	51	aβ	aβ	PRON
fnp-3050	142	52	deposition	deposition	NOUN
fnp-3050	142	53	in	in	ADP
fnp-3050	142	54	and	and	CCONJ
fnp-3050	142	55	around	around	ADP
fnp-3050	142	56	blood	blood	NOUN
fnp-3050	142	57	vessels	vessel	NOUN
fnp-3050	142	58	.	.	PUNCT
fnp-3050	143	1	genetically	genetically	ADV
fnp-3050	143	2	,	,	PUNCT
fnp-3050	143	3	type	type	NOUN
fnp-3050	143	4	3	3	NUM
fnp-3050	143	5	(	(	PUNCT
fnp-3050	143	6	capillary	capillary	ADJ
fnp-3050	143	7	subtype	subtype	NOUN
fnp-3050	143	8	)	)	PUNCT
fnp-3050	143	9	is	be	AUX
fnp-3050	143	10	more	more	ADV
fnp-3050	143	11	strongly	strongly	ADV
fnp-3050	143	12	associated	associate	VERB
fnp-3050	143	13	with	with	ADP
fnp-3050	143	14	the	the	DET
fnp-3050	143	15	apoeε4	apoeε4	PROPN
fnp-3050	143	16	allele	allele	NOUN
fnp-3050	143	17	[	[	X
fnp-3050	143	18	87	87	NUM
fnp-3050	143	19	,	,	PUNCT
fnp-3050	143	20	88	88	NUM
fnp-3050	143	21	]	]	PUNCT
fnp-3050	143	22	.	.	PUNCT
fnp-3050	144	1	two	two	NUM
fnp-3050	144	2	other	other	ADJ
fnp-3050	144	3	types	type	NOUN
fnp-3050	144	4	were	be	AUX
fnp-3050	144	5	distinguished	distinguish	VERB
fnp-3050	144	6	:	:	PUNCT
fnp-3050	144	7	type	type	NOUN
fnp-3050	144	8	1	1	NUM
fnp-3050	144	9	affecting	affect	VERB
fnp-3050	144	10	capillaries	capillary	NOUN
fnp-3050	144	11	,	,	PUNCT
fnp-3050	144	12	arterioles	arteriole	NOUN
fnp-3050	144	13	and	and	CCONJ
fnp-3050	144	14	small	small	ADJ
fnp-3050	144	15	arteries	artery	NOUN
fnp-3050	144	16	is	be	AUX
fnp-3050	144	17	associated	associate	VERB
fnp-3050	144	18	with	with	ADP
fnp-3050	144	19	apoeε4	apoeε4	PROPN
fnp-3050	144	20	,	,	PUNCT
fnp-3050	144	21	whereas	whereas	SCONJ
fnp-3050	144	22	type	type	NOUN
fnp-3050	144	23	2	2	NUM
fnp-3050	144	24	not	not	PART
fnp-3050	144	25	involving	involve	VERB
fnp-3050	144	26	capillaries	capillary	NOUN
fnp-3050	144	27	is	be	AUX
fnp-3050	144	28	more	more	ADV
fnp-3050	144	29	likely	likely	ADV
fnp-3050	144	30	associated	associate	VERB
fnp-3050	144	31	with	with	ADP
fnp-3050	144	32	apoeε2	apoeε2	NOUN
fnp-3050	144	33	,	,	PUNCT
fnp-3050	144	34	its	its	PRON
fnp-3050	144	35	most	most	ADV
fnp-3050	144	36	frequent	frequent	ADJ
fnp-3050	144	37	form	form	NOUN
fnp-3050	144	38	[	[	X
fnp-3050	144	39	89	89	NUM
fnp-3050	144	40	]	]	PUNCT
fnp-3050	144	41	.	.	PUNCT
fnp-3050	145	1	both	both	DET
fnp-3050	145	2	severe	severe	ADJ
fnp-3050	145	3	caa	caa	NOUN
fnp-3050	145	4	and	and	CCONJ
fnp-3050	145	5	ad	ad	NOUN
fnp-3050	145	6	are	be	AUX
fnp-3050	145	7	associated	associate	VERB
fnp-3050	145	8	with	with	ADP
fnp-3050	145	9	apoeε4	apoeε4	PROPN
fnp-3050	145	10	-	-	PUNCT
fnp-3050	145	11	positive	positive	ADJ
fnp-3050	145	12	patients	patient	NOUN
fnp-3050	145	13	[	[	X
fnp-3050	145	14	88	88	NUM
fnp-3050	145	15	]	]	PUNCT
fnp-3050	145	16	.	.	PUNCT
fnp-3050	146	1	a	a	DET
fnp-3050	146	2	more	more	ADV
fnp-3050	146	3	recent	recent	ADJ
fnp-3050	146	4	staging	staging	NOUN
fnp-3050	146	5	system	system	NOUN
fnp-3050	146	6	is	be	AUX
fnp-3050	146	7	based	base	VERB
fnp-3050	146	8	on	on	ADP
fnp-3050	146	9	the	the	DET
fnp-3050	146	10	severity	severity	NOUN
fnp-3050	146	11	of	of	ADP
fnp-3050	146	12	caa	caa	NOUN
fnp-3050	146	13	in	in	ADP
fnp-3050	146	14	a	a	DET
fnp-3050	146	15	single	single	ADJ
fnp-3050	146	16	vessel	vessel	NOUN
fnp-3050	146	17	:	:	PUNCT
fnp-3050	146	18	grade	grade	NOUN
fnp-3050	146	19	0	0	NUM
fnp-3050	146	20	:	:	PUNCT
fnp-3050	146	21	absence	absence	NOUN
fnp-3050	146	22	of	of	ADP
fnp-3050	146	23	staining	stain	VERB
fnp-3050	146	24	,	,	PUNCT
fnp-3050	146	25	grade	grade	NOUN
fnp-3050	146	26	1	1	NUM
fnp-3050	146	27	:	:	PUNCT
fnp-3050	146	28	a	a	DET
fnp-3050	146	29	congophilic	congophilic	ADJ
fnp-3050	146	30	ring	ring	NOUN
fnp-3050	146	31	around	around	ADP
fnp-3050	146	32	the	the	DET
fnp-3050	146	33	otherwise	otherwise	ADV
fnp-3050	146	34	normal	normal	ADJ
fnp-3050	146	35	-	-	PUNCT
fnp-3050	146	36	appearing	appear	VERB
fnp-3050	146	37	vessel	vessel	NOUN
fnp-3050	146	38	,	,	PUNCT
fnp-3050	146	39	grade	grade	NOUN
fnp-3050	146	40	2	2	NUM
fnp-3050	146	41	:	:	PUNCT
fnp-3050	146	42	complete	complete	ADJ
fnp-3050	146	43	replacement	replacement	NOUN
fnp-3050	146	44	of	of	ADP
fnp-3050	146	45	the	the	DET
fnp-3050	146	46	tunica	tunica	PROPN
fnp-3050	146	47	media	medium	NOUN
fnp-3050	146	48	by	by	ADP
fnp-3050	146	49	congophilic	congophilic	ADJ
fnp-3050	146	50	material	material	NOUN
fnp-3050	146	51	,	,	PUNCT
fnp-3050	146	52	grade	grade	NOUN
fnp-3050	146	53	3	3	NUM
fnp-3050	146	54	:	:	PUNCT
fnp-3050	146	55	involving	involve	VERB
fnp-3050	146	56	>	>	SYM
fnp-3050	146	57	50	50	NUM
fnp-3050	146	58	%	%	NOUN
fnp-3050	146	59	of	of	ADP
fnp-3050	146	60	vessel	vessel	NOUN
fnp-3050	146	61	circumference	circumference	NOUN
fnp-3050	146	62	,	,	PUNCT
fnp-3050	146	63	giving	give	VERB
fnp-3050	146	64	a	a	DET
fnp-3050	146	65	“	"	PUNCT
fnp-3050	146	66	double	double	ADJ
fnp-3050	146	67	-	-	PUNCT
fnp-3050	146	68	barrel	barrel	NOUN
fnp-3050	146	69	”	"	PUNCT
fnp-3050	146	70	appearance	appearance	NOUN
fnp-3050	146	71	,	,	PUNCT
fnp-3050	146	72	and	and	CCONJ
fnp-3050	146	73	grade	grade	NOUN
fnp-3050	146	74	4	4	NUM
fnp-3050	146	75	or	or	CCONJ
fnp-3050	146	76	fibrinoid	fibrinoid	ADJ
fnp-3050	146	77	necrosis	necrosis	NOUN
fnp-3050	146	78	of	of	ADP
fnp-3050	146	79	the	the	DET
fnp-3050	146	80	vessel	vessel	NOUN
fnp-3050	146	81	wall	wall	NOUN
fnp-3050	146	82	with	with	ADP
fnp-3050	146	83	additional	additional	ADJ
fnp-3050	146	84	amyloid	amyloid	NOUN
fnp-3050	146	85	deposits	deposit	NOUN
fnp-3050	146	86	in	in	ADP
fnp-3050	146	87	the	the	DET
fnp-3050	146	88	surrounding	surround	VERB
fnp-3050	146	89	neuropil	neuropil	NOUN
fnp-3050	146	90	(	(	PUNCT
fnp-3050	146	91	“	"	PUNCT
fnp-3050	146	92	dyshoric	dyshoric	ADJ
fnp-3050	146	93	changes	change	NOUN
fnp-3050	146	94	”	"	PUNCT
fnp-3050	146	95	)	)	PUNCT
fnp-3050	147	1	[	[	X
fnp-3050	147	2	88	88	NUM
fnp-3050	147	3	]	]	PUNCT
fnp-3050	147	4	.	.	PUNCT
fnp-3050	148	1	the	the	DET
fnp-3050	148	2	parietal	parietal	ADJ
fnp-3050	148	3	and	and	CCONJ
fnp-3050	148	4	occipital	occipital	ADJ
fnp-3050	148	5	cortices	cortex	NOUN
fnp-3050	148	6	are	be	AUX
fnp-3050	148	7	more	more	ADV
fnp-3050	148	8	vulnerable	vulnerable	ADJ
fnp-3050	148	9	than	than	ADP
fnp-3050	148	10	the	the	DET
fnp-3050	148	11	frontal	frontal	ADJ
fnp-3050	148	12	and	and	CCONJ
fnp-3050	148	13	temporal	temporal	ADJ
fnp-3050	148	14	lobe	lobe	NOUN
fnp-3050	148	15	,	,	PUNCT
fnp-3050	148	16	and	and	CCONJ
fnp-3050	148	17	the	the	DET
fnp-3050	148	18	leptomeningeal	leptomeningeal	NOUN
fnp-3050	148	19	vessels	vessel	NOUN
fnp-3050	148	20	more	more	ADJ
fnp-3050	148	21	than	than	ADP
fnp-3050	148	22	the	the	DET
fnp-3050	148	23	parenchymal	parenchymal	ADJ
fnp-3050	148	24	ones	one	NOUN
fnp-3050	148	25	[	[	X
fnp-3050	148	26	84	84	NUM
fnp-3050	148	27	]	]	PUNCT
fnp-3050	148	28	.	.	PUNCT
fnp-3050	149	1	aβ	aβ	PRON
fnp-3050	149	2	deposition	deposition	NOUN
fnp-3050	149	3	shrinks	shrink	VERB
fnp-3050	149	4	the	the	DET
fnp-3050	149	5	cerebral	cerebral	ADJ
fnp-3050	149	6	blood	blood	NOUN
fnp-3050	149	7	vessels	vessel	NOUN
fnp-3050	149	8	by	by	ADP
fnp-3050	149	9	about	about	ADV
fnp-3050	149	10	8	8	NUM
fnp-3050	149	11	%	%	NOUN
fnp-3050	149	12	and	and	CCONJ
fnp-3050	149	13	reduces	reduce	VERB
fnp-3050	149	14	the	the	DET
fnp-3050	149	15	energy	energy	NOUN
fnp-3050	149	16	supply	supply	NOUN
fnp-3050	149	17	resulting	result	VERB
fnp-3050	149	18	from	from	ADP
fnp-3050	149	19	decrease	decrease	NOUN
fnp-3050	149	20	of	of	ADP
fnp-3050	149	21	blood	blood	NOUN
fnp-3050	149	22	flow	flow	NOUN
fnp-3050	149	23	[	[	X
fnp-3050	149	24	90	90	NUM
fnp-3050	149	25	]	]	PUNCT
fnp-3050	149	26	.	.	PUNCT
fnp-3050	150	1	caa	caa	PROPN
fnp-3050	150	2	can	can	AUX
fnp-3050	150	3	cause	cause	VERB
fnp-3050	150	4	small	small	ADJ
fnp-3050	150	5	infarcts	infarct	NOUN
fnp-3050	150	6	in	in	ADP
fnp-3050	150	7	the	the	DET
fnp-3050	150	8	cerebral	cerebral	ADJ
fnp-3050	150	9	cortex	cortex	NOUN
fnp-3050	150	10	,	,	PUNCT
fnp-3050	150	11	while	while	SCONJ
fnp-3050	150	12	severe	severe	ADJ
fnp-3050	150	13	caa	caa	NOUN
fnp-3050	150	14	may	may	AUX
fnp-3050	150	15	lead	lead	VERB
fnp-3050	150	16	to	to	ADP
fnp-3050	150	17	lobar	lobar	ADJ
fnp-3050	150	18	hemorrhages	hemorrhage	NOUN
fnp-3050	150	19	in	in	ADP
fnp-3050	150	20	the	the	DET
fnp-3050	150	21	frontal	frontal	ADJ
fnp-3050	150	22	and	and	CCONJ
fnp-3050	150	23	occipital	occipital	NOUN
fnp-3050	150	24	lobes	lobe	NOUN
fnp-3050	150	25	and	and	CCONJ
fnp-3050	150	26	to	to	PART
fnp-3050	150	27	diffuse	diffuse	VERB
fnp-3050	150	28	white	white	ADJ
fnp-3050	150	29	matter	matter	NOUN
fnp-3050	150	30	lesions	lesion	NOUN
fnp-3050	150	31	(	(	PUNCT
fnp-3050	150	32	fig	fig	NOUN
fnp-3050	150	33	.	.	PUNCT
fnp-3050	151	1	4	4	X
fnp-3050	151	2	)	)	PUNCT
fnp-3050	152	1	[	[	X
fnp-3050	152	2	91	91	NUM
fnp-3050	152	3	]	]	PUNCT
fnp-3050	152	4	.	.	PUNCT
fnp-3050	153	1	brain	brain	NOUN
fnp-3050	153	2	hemorrhage	hemorrhage	NOUN
fnp-3050	153	3	does	do	AUX
fnp-3050	153	4	not	not	PART
fnp-3050	153	5	appear	appear	VERB
fnp-3050	153	6	to	to	PART
fnp-3050	153	7	be	be	AUX
fnp-3050	153	8	directly	directly	ADV
fnp-3050	153	9	linked	link	VERB
fnp-3050	153	10	to	to	ADP
fnp-3050	153	11	amyloid	amyloid	NOUN
fnp-3050	153	12	burden	burden	NOUN
fnp-3050	153	13	in	in	ADP
fnp-3050	153	14	patients	patient	NOUN
fnp-3050	153	15	with	with	ADP
fnp-3050	153	16	caa	caa	NOUN
fnp-3050	153	17	-	-	PUNCT
fnp-3050	153	18	related	relate	VERB
fnp-3050	153	19	intracerebral	intracerebral	ADJ
fnp-3050	153	20	hemorrhage	hemorrhage	NOUN
fnp-3050	153	21	,	,	PUNCT
fnp-3050	153	22	because	because	SCONJ
fnp-3050	153	23	amyloid	amyloid	NOUN
fnp-3050	153	24	burden	burden	NOUN
fnp-3050	153	25	was	be	AUX
fnp-3050	153	26	similarly	similarly	ADV
fnp-3050	153	27	distributed	distribute	VERB
fnp-3050	153	28	across	across	ADP
fnp-3050	153	29	the	the	DET
fnp-3050	153	30	brain	brain	NOUN
fnp-3050	153	31	hemispheres	hemisphere	NOUN
fnp-3050	153	32	and	and	CCONJ
fnp-3050	153	33	no	no	DET
fnp-3050	153	34	interhemispheric	interhemispheric	ADJ
fnp-3050	153	35	difference	difference	NOUN
fnp-3050	153	36	was	be	AUX
fnp-3050	153	37	observed	observe	VERB
fnp-3050	153	38	for	for	ADP
fnp-3050	153	39	aβ	aβ	NOUN
fnp-3050	153	40	burden	burden	NOUN
fnp-3050	153	41	nor	nor	CCONJ
fnp-3050	153	42	for	for	ADP
fnp-3050	153	43	mri	mri	NOUN
fnp-3050	153	44	markers	marker	NOUN
fnp-3050	153	45	of	of	ADP
fnp-3050	153	46	small	small	ADJ
fnp-3050	153	47	vessel	vessel	NOUN
fnp-3050	153	48	disease	disease	NOUN
fnp-3050	153	49	[	[	X
fnp-3050	153	50	92	92	NUM
fnp-3050	153	51	]	]	PUNCT
fnp-3050	153	52	.	.	PUNCT
fnp-3050	154	1	caa	caa	PROPN
fnp-3050	154	2	and	and	CCONJ
fnp-3050	154	3	deep	deep	ADJ
fnp-3050	154	4	perforating	perforate	VERB
fnp-3050	154	5	arteriopathy	arteriopathy	ADJ
fnp-3050	154	6	are	be	AUX
fnp-3050	154	7	similar	similar	ADJ
fnp-3050	154	8	and	and	CCONJ
fnp-3050	154	9	interact	interact	VERB
fnp-3050	154	10	with	with	ADP
fnp-3050	154	11	blood	blood	NOUN
fnp-3050	154	12	-	-	PUNCT
fnp-3050	154	13	brain	brain	NOUN
fnp-3050	154	14	barrier	barrier	NOUN
fnp-3050	154	15	breakdown	breakdown	NOUN
fnp-3050	154	16	,	,	PUNCT
fnp-3050	154	17	endothelial	endothelial	ADJ
fnp-3050	154	18	damage	damage	NOUN
fnp-3050	154	19	,	,	PUNCT
fnp-3050	154	20	and	and	CCONJ
fnp-3050	154	21	impaired	impaired	ADJ
fnp-3050	154	22	perivascular	perivascular	ADJ
fnp-3050	154	23	aβ	aβ	NOUN
fnp-3050	154	24	drainage	drainage	NOUN
fnp-3050	154	25	.	.	PUNCT
fnp-3050	155	1	both	both	PRON
fnp-3050	155	2	may	may	AUX
fnp-3050	155	3	cause	cause	VERB
fnp-3050	155	4	ischemic	ischemic	ADJ
fnp-3050	155	5	lesions	lesion	NOUN
fnp-3050	155	6	and	and	CCONJ
fnp-3050	155	7	intracerebral	intracerebral	ADJ
fnp-3050	155	8	hemorrhages	hemorrhage	NOUN
fnp-3050	155	9	[	[	X
fnp-3050	155	10	93	93	NUM
fnp-3050	155	11	]	]	PUNCT
fnp-3050	155	12	.	.	PUNCT
fnp-3050	156	1	chronic	chronic	ADJ
fnp-3050	156	2	treatment	treatment	NOUN
fnp-3050	156	3	of	of	ADP
fnp-3050	156	4	a	a	DET
fnp-3050	156	5	mouse	mouse	NOUN
fnp-3050	156	6	model	model	NOUN
fnp-3050	156	7	of	of	ADP
fnp-3050	156	8	ad	ad	NOUN
fnp-3050	156	9	with	with	ADP
fnp-3050	156	10	fungicides	fungicide	NOUN
fnp-3050	156	11	produced	produce	VERB
fnp-3050	156	12	aβ	aβ	PRON
fnp-3050	156	13	fibril	fibril	ADJ
fnp-3050	156	14	formation	formation	NOUN
fnp-3050	156	15	and	and	CCONJ
fnp-3050	156	16	impairment	impairment	NOUN
fnp-3050	156	17	of	of	ADP
fnp-3050	156	18	aβ	aβ	NOUN
fnp-3050	156	19	clearance	clearance	NOUN
fnp-3050	156	20	through	through	ADP
fnp-3050	156	21	neprylisin	neprylisin	NOUN
fnp-3050	156	22	,	,	PUNCT
fnp-3050	156	23	suggesting	suggest	VERB
fnp-3050	156	24	that	that	SCONJ
fnp-3050	156	25	fungicide	fungicide	NOUN
fnp-3050	156	26	residues	residue	NOUN
fnp-3050	156	27	could	could	AUX
fnp-3050	156	28	be	be	AUX
fnp-3050	156	29	a	a	DET
fnp-3050	156	30	risk	risk	NOUN
fnp-3050	156	31	factor	factor	NOUN
fnp-3050	156	32	for	for	ADP
fnp-3050	156	33	ad	ad	NOUN
fnp-3050	156	34	via	via	ADP
fnp-3050	156	35	caa	caa	NOUN
fnp-3050	156	36	[	[	X
fnp-3050	156	37	94	94	NUM
fnp-3050	156	38	]	]	PUNCT
fnp-3050	156	39	.	.	PUNCT
fnp-3050	157	1	although	although	SCONJ
fnp-3050	157	2	several	several	ADJ
fnp-3050	157	3	pathogenic	pathogenic	ADJ
fnp-3050	157	4	mechanisms	mechanism	NOUN
fnp-3050	157	5	,	,	PUNCT
fnp-3050	157	6	including	include	VERB
fnp-3050	157	7	the	the	DET
fnp-3050	157	8	disbalance	disbalance	NOUN
fnp-3050	157	9	between	between	ADP
fnp-3050	157	10	production	production	NOUN
fnp-3050	157	11	and	and	CCONJ
fnp-3050	157	12	clearance	clearance	NOUN
fnp-3050	157	13	of	of	ADP
fnp-3050	157	14	aβ	aβ	NOUN
fnp-3050	157	15	creating	create	VERB
fnp-3050	157	16	a	a	DET
fnp-3050	157	17	self	self	NOUN
fnp-3050	157	18	-	-	PUNCT
fnp-3050	157	19	reinforcing	reinforce	VERB
fnp-3050	157	20	cycle	cycle	NOUN
fnp-3050	157	21	of	of	ADP
fnp-3050	157	22	increased	increase	VERB
fnp-3050	157	23	vascular	vascular	ADJ
fnp-3050	157	24	aβ	aβ	NOUN
fnp-3050	157	25	and	and	CCONJ
fnp-3050	157	26	further	further	ADJ
fnp-3050	157	27	caa	caa	NOUN
fnp-3050	157	28	and	and	CCONJ
fnp-3050	157	29	ad	ad	NOUN
fnp-3050	157	30	progression	progression	NOUN
fnp-3050	157	31	,	,	PUNCT
fnp-3050	157	32	have	have	AUX
fnp-3050	157	33	been	be	AUX
fnp-3050	157	34	shown	show	VERB
fnp-3050	157	35	,	,	PUNCT
fnp-3050	157	36	they	they	PRON
fnp-3050	157	37	do	do	AUX
fnp-3050	157	38	not	not	PART
fnp-3050	157	39	explain	explain	VERB
fnp-3050	157	40	completely	completely	ADV
fnp-3050	157	41	the	the	DET
fnp-3050	157	42	disease	disease	NOUN
fnp-3050	157	43	pathogenesis	pathogenesis	NOUN
fnp-3050	157	44	[	[	X
fnp-3050	157	45	95	95	NUM
fnp-3050	157	46	]	]	PUNCT
fnp-3050	157	47	.	.	PUNCT
fnp-3050	158	1	the	the	DET
fnp-3050	158	2	intersection	intersection	NOUN
fnp-3050	158	3	between	between	ADP
fnp-3050	158	4	caa	caa	NOUN
fnp-3050	158	5	and	and	CCONJ
fnp-3050	158	6	ad	ad	NOUN
fnp-3050	158	7	points	point	NOUN
fnp-3050	158	8	to	to	ADP
fnp-3050	158	9	a	a	DET
fnp-3050	158	10	crucial	crucial	ADJ
fnp-3050	158	11	role	role	NOUN
fnp-3050	158	12	for	for	ADP
fnp-3050	158	13	improving	improve	VERB
fnp-3050	158	14	vascular	vascular	ADJ
fnp-3050	158	15	function	function	NOUN
fnp-3050	158	16	in	in	ADP
fnp-3050	158	17	the	the	DET
fnp-3050	158	18	treatment	treatment	NOUN
fnp-3050	158	19	of	of	ADP
fnp-3050	158	20	ad	ad	NOUN
fnp-3050	158	21	[	[	X
fnp-3050	158	22	96	96	NUM
fnp-3050	158	23	]	]	PUNCT
fnp-3050	158	24	.	.	PUNCT
fnp-3050	159	1	figure	figure	NOUN
fnp-3050	159	2	4	4	NUM
fnp-3050	159	3	.	.	PUNCT
fnp-3050	160	1	multiple	multiple	ADJ
fnp-3050	160	2	large	large	ADJ
fnp-3050	160	3	hemorrhages	hemorrhage	NOUN
fnp-3050	160	4	in	in	ADP
fnp-3050	160	5	both	both	DET
fnp-3050	160	6	frontal	frontal	ADJ
fnp-3050	160	7	lobes	lobe	NOUN
fnp-3050	160	8	(	(	PUNCT
fnp-3050	160	9	a	a	NOUN
fnp-3050	160	10	)	)	PUNCT
fnp-3050	160	11	and	and	CCONJ
fnp-3050	160	12	occipital	occipital	NOUN
fnp-3050	160	13	lobe	lobe	NOUN
fnp-3050	160	14	(	(	PUNCT
fnp-3050	160	15	b	b	NOUN
fnp-3050	160	16	)	)	PUNCT
fnp-3050	160	17	.	.	PUNCT
fnp-3050	161	1	diffuse	diffuse	VERB
fnp-3050	161	2	white	white	ADJ
fnp-3050	161	3	matter	matter	NOUN
fnp-3050	161	4	destruction	destruction	NOUN
fnp-3050	161	5	(	(	PUNCT
fnp-3050	161	6	c	c	NOUN
fnp-3050	161	7	)	)	PUNCT
fnp-3050	161	8	.	.	PUNCT
fnp-3050	162	1	caa	caa	NOUN
fnp-3050	162	2	in	in	ADP
fnp-3050	162	3	many	many	ADJ
fnp-3050	162	4	vessels	vessel	NOUN
fnp-3050	162	5	in	in	ADP
fnp-3050	162	6	the	the	DET
fnp-3050	162	7	cerebral	cerebral	ADJ
fnp-3050	162	8	white	white	ADJ
fnp-3050	162	9	matter	matter	NOUN
fnp-3050	162	10	;	;	PUNCT
fnp-3050	162	11	scale	scale	NOUN
fnp-3050	162	12	bar	bar	NOUN
fnp-3050	162	13	70	70	NUM
fnp-3050	162	14	µm	µm	NOUN
fnp-3050	162	15	(	(	PUNCT
fnp-3050	162	16	d	d	NOUN
fnp-3050	162	17	)	)	PUNCT
fnp-3050	162	18	.	.	PUNCT
fnp-3050	163	1	from	from	ADP
fnp-3050	163	2	[	[	X
fnp-3050	163	3	97	97	NUM
fnp-3050	163	4	]	]	PUNCT
fnp-3050	163	5	.	.	PUNCT
fnp-3050	164	1	2.6	2.6	NUM
fnp-3050	164	2	.	.	PUNCT
fnp-3050	165	1	tau	tau	PROPN
fnp-3050	165	2	pathology	pathology	PROPN
fnp-3050	165	3	tau	tau	PROPN
fnp-3050	165	4	protein	protein	NOUN
fnp-3050	165	5	is	be	AUX
fnp-3050	165	6	encoded	encode	VERB
fnp-3050	165	7	by	by	ADP
fnp-3050	165	8	the	the	DET
fnp-3050	165	9	mapt	mapt	NOUN
fnp-3050	165	10	(	(	PUNCT
fnp-3050	165	11	microtubule	microtubule	NOUN
fnp-3050	165	12	-	-	PUNCT
fnp-3050	165	13	associated	associate	VERB
fnp-3050	165	14	protein	protein	NOUN
fnp-3050	165	15	tau	tau	NOUN
fnp-3050	165	16	)	)	PUNCT
fnp-3050	165	17	gene	gene	NOUN
fnp-3050	165	18	on	on	ADP
fnp-3050	165	19	chromosome	chromosome	NOUN
fnp-3050	165	20	17	17	NUM
fnp-3050	165	21	[	[	X
fnp-3050	165	22	98	98	NUM
fnp-3050	165	23	]	]	PUNCT
fnp-3050	165	24	,	,	PUNCT
fnp-3050	165	25	which	which	PRON
fnp-3050	165	26	generates	generate	VERB
fnp-3050	165	27	a	a	DET
fnp-3050	165	28	total	total	NOUN
fnp-3050	165	29	of	of	ADP
fnp-3050	165	30	6	6	NUM
fnp-3050	165	31	isoforms	isoform	NOUN
fnp-3050	165	32	through	through	ADP
fnp-3050	165	33	alternative	alternative	ADJ
fnp-3050	165	34	splicing	splicing	NOUN
fnp-3050	165	35	of	of	ADP
fnp-3050	165	36	exons	exon	NOUN
fnp-3050	165	37	2	2	NUM
fnp-3050	165	38	,	,	PUNCT
fnp-3050	165	39	3	3	NUM
fnp-3050	165	40	and	and	CCONJ
fnp-3050	165	41	10	10	NUM
fnp-3050	165	42	in	in	ADP
fnp-3050	165	43	the	the	DET
fnp-3050	165	44	cns	cns	NOUN
fnp-3050	166	1	[	[	X
fnp-3050	166	2	99	99	NUM
fnp-3050	166	3	]	]	PUNCT
fnp-3050	166	4	.	.	PUNCT
fnp-3050	167	1	tau	tau	PROPN
fnp-3050	167	2	protein	protein	NOUN
fnp-3050	167	3	,	,	PUNCT
fnp-3050	167	4	the	the	DET
fnp-3050	167	5	main	main	ADJ
fnp-3050	167	6	constituent	constituent	NOUN
fnp-3050	167	7	of	of	ADP
fnp-3050	167	8	nfts	nft	NOUN
fnp-3050	167	9	,	,	PUNCT
fnp-3050	167	10	is	be	AUX
fnp-3050	167	11	involved	involve	VERB
fnp-3050	167	12	in	in	ADP
fnp-3050	167	13	the	the	DET
fnp-3050	167	14	stabilization	stabilization	NOUN
fnp-3050	167	15	of	of	ADP
fnp-3050	167	16	neurotubules	neurotubule	NOUN
fnp-3050	167	17	that	that	PRON
fnp-3050	167	18	leads	lead	VERB
fnp-3050	167	19	to	to	ADP
fnp-3050	167	20	the	the	DET
fnp-3050	167	21	appropriate	appropriate	ADJ
fnp-3050	167	22	function	function	NOUN
fnp-3050	167	23	of	of	ADP
fnp-3050	167	24	the	the	DET
fnp-3050	167	25	neuron	neuron	NOUN
fnp-3050	167	26	.	.	PUNCT
fnp-3050	168	1	its	its	PRON
fnp-3050	168	2	microtubule	microtubule	NOUN
fnp-3050	168	3	-	-	PUNCT
fnp-3050	168	4	binding	bind	VERB
fnp-3050	168	5	regions	region	NOUN
fnp-3050	168	6	are	be	AUX
fnp-3050	168	7	made	make	VERB
fnp-3050	168	8	of	of	ADP
fnp-3050	168	9	3	3	NUM
fnp-3050	168	10	or	or	CCONJ
fnp-3050	168	11	4	4	NUM
fnp-3050	168	12	repeats	repeat	NOUN
fnp-3050	168	13	(	(	PUNCT
fnp-3050	168	14	3r	3r	NUM
fnp-3050	168	15	or	or	CCONJ
fnp-3050	168	16	4r	4r	NUM
fnp-3050	168	17	tau	tau	PROPN
fnp-3050	168	18	)	)	PUNCT
fnp-3050	168	19	,	,	PUNCT
fnp-3050	168	20	their	their	PRON
fnp-3050	168	21	second	second	ADJ
fnp-3050	168	22	repeat	repeat	NOUN
fnp-3050	168	23	(	(	PUNCT
fnp-3050	168	24	exon	exon	NOUN
fnp-3050	168	25	10	10	NUM
fnp-3050	168	26	)	)	PUNCT
fnp-3050	168	27	being	be	AUX
fnp-3050	168	28	spliced	splice	VERB
fnp-3050	168	29	in	in	ADP
fnp-3050	168	30	some	some	DET
fnp-3050	168	31	isoforms	isoform	NOUN
fnp-3050	168	32	.	.	PUNCT
fnp-3050	169	1	combined	combined	ADJ
fnp-3050	169	2	phosphorylation	phosphorylation	NOUN
fnp-3050	169	3	of	of	ADP
fnp-3050	169	4	ser202	ser202	PROPN
fnp-3050	169	5	,	,	PUNCT
fnp-3050	169	6	thr205	thr205	PROPN
fnp-3050	169	7	,	,	PUNCT
fnp-3050	169	8	and	and	CCONJ
fnp-3050	169	9	ser208	ser208	NOUN
fnp-3050	169	10	forms	form	VERB
fnp-3050	169	11	a	a	DET
fnp-3050	169	12	unique	unique	ADJ
fnp-3050	169	13	post	post	ADJ
fnp-3050	169	14	-	-	ADJ
fnp-3050	169	15	translational	translational	ADJ
fnp-3050	169	16	modification	modification	NOUN
fnp-3050	169	17	configuration	configuration	NOUN
fnp-3050	169	18	that	that	PRON
fnp-3050	169	19	promotes	promote	VERB
fnp-3050	169	20	tau	tau	PROPN
fnp-3050	169	21	aggregation	aggregation	NOUN
fnp-3050	169	22	,	,	PUNCT
fnp-3050	169	23	accelerating	accelerate	VERB
fnp-3050	169	24	the	the	DET
fnp-3050	169	25	formation	formation	NOUN
fnp-3050	169	26	of	of	ADP
fnp-3050	169	27	tau	tau	PROPN
fnp-3050	169	28	filaments	filament	NOUN
fnp-3050	169	29	and	and	CCONJ
fnp-3050	169	30	eventually	eventually	ADV
fnp-3050	169	31	resulting	result	VERB
fnp-3050	169	32	in	in	ADP
fnp-3050	169	33	nft	nft	PROPN
fnp-3050	169	34	formation	formation	NOUN
fnp-3050	169	35	.	.	PUNCT
fnp-3050	170	1	tau	tau	PROPN
fnp-3050	170	2	adopts	adopt	VERB
fnp-3050	170	3	different	different	ADJ
fnp-3050	170	4	stable	stable	ADJ
fnp-3050	170	5	conformations	conformation	NOUN
fnp-3050	170	6	,	,	PUNCT
fnp-3050	170	7	consistent	consistent	ADJ
fnp-3050	170	8	with	with	ADP
fnp-3050	170	9	the	the	DET
fnp-3050	170	10	notion	notion	NOUN
fnp-3050	170	11	of	of	ADP
fnp-3050	170	12	'	'	PUNCT
fnp-3050	170	13	strains	strain	NOUN
fnp-3050	170	14	'	'	PUNCT
fnp-3050	170	15	as	as	SCONJ
fnp-3050	170	16	may	may	AUX
fnp-3050	170	17	be	be	AUX
fnp-3050	170	18	seen	see	VERB
fnp-3050	170	19	with	with	ADP
fnp-3050	170	20	the	the	DET
fnp-3050	170	21	concept	concept	NOUN
fnp-3050	170	22	of	of	ADP
fnp-3050	170	23	phenotypic	phenotypic	ADJ
fnp-3050	170	24	diversity	diversity	NOUN
fnp-3050	170	25	or	or	CCONJ
fnp-3050	170	26	with	with	ADP
fnp-3050	170	27	different	different	ADJ
fnp-3050	170	28	environmental	environmental	ADJ
fnp-3050	170	29	stimuli	stimulus	NOUN
fnp-3050	170	30	[	[	X
fnp-3050	170	31	100	100	NUM
fnp-3050	170	32	,	,	PUNCT
fnp-3050	170	33	101	101	NUM
fnp-3050	170	34	]	]	PUNCT
fnp-3050	170	35	.	.	PUNCT
fnp-3050	171	1	truncation	truncation	NOUN
fnp-3050	171	2	of	of	ADP
fnp-3050	171	3	tau	tau	PROPN
fnp-3050	171	4	by	by	ADP
fnp-3050	171	5	caspases-3	caspases-3	NUM
fnp-3050	171	6	or	or	CCONJ
fnp-3050	171	7	-4	-4	PRON
fnp-3050	171	8	is	be	AUX
fnp-3050	171	9	an	an	DET
fnp-3050	171	10	early	early	ADJ
fnp-3050	171	11	event	event	NOUN
fnp-3050	171	12	in	in	ADP
fnp-3050	171	13	the	the	DET
fnp-3050	171	14	development	development	NOUN
fnp-3050	171	15	of	of	ADP
fnp-3050	171	16	nfts	nft	NOUN
fnp-3050	171	17	[	[	X
fnp-3050	171	18	102	102	NUM
fnp-3050	171	19	]	]	PUNCT
fnp-3050	171	20	.	.	PUNCT
fnp-3050	172	1	the	the	DET
fnp-3050	172	2	molecular	molecular	ADJ
fnp-3050	172	3	mechanisms	mechanism	NOUN
fnp-3050	172	4	leading	lead	VERB
fnp-3050	172	5	to	to	ADP
fnp-3050	172	6	the	the	DET
fnp-3050	172	7	accumulation	accumulation	NOUN
fnp-3050	172	8	of	of	ADP
fnp-3050	172	9	tau	tau	PROPN
fnp-3050	172	10	are	be	AUX
fnp-3050	172	11	characterized	characterize	VERB
fnp-3050	172	12	by	by	ADP
fnp-3050	172	13	numerous	numerous	ADJ
fnp-3050	172	14	translational	translational	ADJ
fnp-3050	172	15	modifications	modification	NOUN
fnp-3050	172	16	that	that	PRON
fnp-3050	172	17	change	change	VERB
fnp-3050	172	18	its	its	PRON
fnp-3050	172	19	conformation	conformation	NOUN
fnp-3050	172	20	and	and	CCONJ
fnp-3050	172	21	structural	structural	ADJ
fnp-3050	172	22	state	state	NOUN
fnp-3050	172	23	.	.	PUNCT
fnp-3050	173	1	recent	recent	ADJ
fnp-3050	173	2	studies	study	NOUN
fnp-3050	173	3	indicate	indicate	VERB
fnp-3050	173	4	that	that	SCONJ
fnp-3050	173	5	the	the	DET
fnp-3050	173	6	dysregulation	dysregulation	NOUN
fnp-3050	173	7	and	and	CCONJ
fnp-3050	173	8	dislocation	dislocation	NOUN
fnp-3050	173	9	of	of	ADP
fnp-3050	173	10	splicing	splicing	NOUN
fnp-3050	173	11	factor	factor	NOUN
fnp-3050	173	12	proline	proline	NOUN
fnp-3050	173	13	and	and	CCONJ
fnp-3050	173	14	glutamine	glutamine	NOUN
fnp-3050	173	15	rich	rich	ADJ
fnp-3050	173	16	(	(	PUNCT
fnp-3050	173	17	sfpq	sfpq	NOUN
fnp-3050	173	18	)	)	PUNCT
fnp-3050	173	19	,	,	PUNCT
fnp-3050	173	20	the	the	DET
fnp-3050	173	21	subsequent	subsequent	ADJ
fnp-3050	173	22	dna	dna	PROPN
fnp-3050	173	23	anomalies	anomaly	NOUN
fnp-3050	173	24	and	and	CCONJ
fnp-3050	173	25	aberrant	aberrant	ADJ
fnp-3050	173	26	dynamics	dynamic	NOUN
fnp-3050	173	27	of	of	ADP
fnp-3050	173	28	tia-1	tia-1	VERB
fnp-3050	173	29	-	-	ADJ
fnp-3050	173	30	positive	positive	ADJ
fnp-3050	173	31	stress	stress	NOUN
fnp-3050	173	32	granules	granule	NOUN
fnp-3050	173	33	in	in	ADP
fnp-3050	173	34	association	association	NOUN
fnp-3050	173	35	with	with	ADP
fnp-3050	173	36	pathological	pathological	ADJ
fnp-3050	173	37	tau	tau	PROPN
fnp-3050	173	38	may	may	AUX
fnp-3050	173	39	represent	represent	VERB
fnp-3050	173	40	a	a	DET
fnp-3050	173	41	critical	critical	ADJ
fnp-3050	173	42	pathway	pathway	NOUN
fnp-3050	173	43	which	which	PRON
fnp-3050	173	44	contributes	contribute	VERB
fnp-3050	173	45	to	to	ADP
fnp-3050	173	46	the	the	DET
fnp-3050	173	47	rapid	rapid	ADJ
fnp-3050	173	48	progression	progression	NOUN
fnp-3050	173	49	of	of	ADP
fnp-3050	173	50	ad	ad	NOUN
fnp-3050	173	51	[	[	X
fnp-3050	173	52	103	103	NUM
fnp-3050	173	53	]	]	PUNCT
fnp-3050	173	54	.	.	PUNCT
fnp-3050	174	1	abberant	abberant	ADJ
fnp-3050	174	2	phosphorylation	phosphorylation	NOUN
fnp-3050	174	3	and	and	CCONJ
fnp-3050	174	4	truncation	truncation	NOUN
fnp-3050	174	5	make	make	VERB
fnp-3050	174	6	tau	tau	NOUN
fnp-3050	174	7	protein	protein	NOUN
fnp-3050	174	8	into	into	ADP
fnp-3050	174	9	a	a	DET
fnp-3050	174	10	pathological	pathological	ADJ
fnp-3050	174	11	entity	entity	NOUN
fnp-3050	174	12	;	;	PUNCT
fnp-3050	174	13	paired	pair	VERB
fnp-3050	174	14	helical	helical	ADJ
fnp-3050	174	15	filaments	filament	NOUN
fnp-3050	174	16	(	(	PUNCT
fnp-3050	174	17	phf	phf	NOUN
fnp-3050	174	18	)	)	PUNCT
fnp-3050	174	19	,	,	PUNCT
fnp-3050	174	20	the	the	DET
fnp-3050	174	21	major	major	ADJ
fnp-3050	174	22	structural	structural	ADJ
fnp-3050	174	23	constituents	constituent	NOUN
fnp-3050	174	24	of	of	ADP
fnp-3050	174	25	nfts	nft	NOUN
fnp-3050	174	26	,	,	PUNCT
fnp-3050	174	27	exhibit	exhibit	VERB
fnp-3050	174	28	a	a	DET
fnp-3050	174	29	greater	great	ADJ
fnp-3050	174	30	degree	degree	NOUN
fnp-3050	174	31	of	of	ADP
fnp-3050	174	32	phosphorylation	phosphorylation	NOUN
fnp-3050	174	33	than	than	ADP
fnp-3050	174	34	normal	normal	ADJ
fnp-3050	174	35	tau	tau	PROPN
fnp-3050	175	1	[	[	X
fnp-3050	175	2	104].tau	104].tau	NUM
fnp-3050	175	3	monomers	monomer	NOUN
fnp-3050	175	4	can	can	AUX
fnp-3050	175	5	aggregate	aggregate	VERB
fnp-3050	175	6	to	to	PART
fnp-3050	175	7	form	form	VERB
fnp-3050	175	8	oligomers	oligomer	NOUN
fnp-3050	175	9	and	and	CCONJ
fnp-3050	175	10	higher	high	ADJ
fnp-3050	175	11	-	-	PUNCT
fnp-3050	175	12	order	order	NOUN
fnp-3050	175	13	fibrils	fibril	NOUN
fnp-3050	175	14	.	.	PUNCT
fnp-3050	176	1	whilst	whilst	SCONJ
fnp-3050	176	2	aβ	aβ	PRON
fnp-3050	176	3	can	can	AUX
fnp-3050	176	4	largely	largely	ADV
fnp-3050	176	5	self	self	NOUN
fnp-3050	176	6	assemble	assemble	ADJ
fnp-3050	176	7	,	,	PUNCT
fnp-3050	176	8	tau	tau	PROPN
fnp-3050	176	9	phosphorylation	phosphorylation	NOUN
fnp-3050	176	10	is	be	AUX
fnp-3050	176	11	believed	believe	VERB
fnp-3050	176	12	to	to	PART
fnp-3050	176	13	be	be	AUX
fnp-3050	176	14	important	important	ADJ
fnp-3050	176	15	for	for	ADP
fnp-3050	176	16	its	its	PRON
fnp-3050	176	17	aggregation	aggregation	NOUN
fnp-3050	177	1	[	[	X
fnp-3050	177	2	105	105	NUM
fnp-3050	177	3	]	]	PUNCT
fnp-3050	177	4	.	.	PUNCT
fnp-3050	178	1	phosphorylation	phosphorylation	NOUN
fnp-3050	178	2	of	of	ADP
fnp-3050	178	3	ser208	ser208	NOUN
fnp-3050	178	4	likely	likely	ADV
fnp-3050	178	5	occurs	occur	VERB
fnp-3050	178	6	at	at	ADP
fnp-3050	178	7	different	different	ADJ
fnp-3050	178	8	disease	disease	NOUN
fnp-3050	178	9	stages	stage	NOUN
fnp-3050	178	10	from	from	ADP
fnp-3050	178	11	phosphorylation	phosphorylation	NOUN
fnp-3050	178	12	of	of	ADP
fnp-3050	178	13	ser202	ser202	PROPN
fnp-3050	178	14	and	and	CCONJ
fnp-3050	178	15	thr205	thr205	PROPN
fnp-3050	178	16	.	.	PUNCT
fnp-3050	179	1	hp	hp	PROPN
fnp-3050	179	2	-	-	PUNCT
fnp-3050	179	3	tau	tau	PROPN
fnp-3050	179	4	accumulation	accumulation	NOUN
fnp-3050	179	5	causes	cause	VERB
fnp-3050	179	6	synaptic	synaptic	ADJ
fnp-3050	179	7	impairment	impairment	NOUN
fnp-3050	179	8	,	,	PUNCT
fnp-3050	179	9	neuronal	neuronal	ADJ
fnp-3050	179	10	dysfunction	dysfunction	NOUN
fnp-3050	179	11	,	,	PUNCT
fnp-3050	179	12	and	and	CCONJ
fnp-3050	179	13	formation	formation	NOUN
fnp-3050	179	14	of	of	ADP
fnp-3050	179	15	nfts	nft	NOUN
fnp-3050	179	16	.	.	PUNCT
fnp-3050	180	1	tau	tau	PROPN
fnp-3050	180	2	with	with	ADP
fnp-3050	180	3	site	site	NOUN
fnp-3050	180	4	-	-	PUNCT
fnp-3050	180	5	specific	specific	ADJ
fnp-3050	180	6	posttranslational	posttranslational	ADJ
fnp-3050	180	7	modification	modification	NOUN
fnp-3050	180	8	/	/	SYM
fnp-3050	180	9	soluble	soluble	ADJ
fnp-3050	180	10	hp	hp	ADJ
fnp-3050	180	11	-	-	PUNCT
fnp-3050	180	12	tau	tau	PROPN
fnp-3050	180	13	species	specie	NOUN
fnp-3050	180	14	impact	impact	NOUN
fnp-3050	180	15	mitochondria	mitochondria	NOUN
fnp-3050	180	16	and	and	CCONJ
fnp-3050	180	17	facilitate	facilitate	ADJ
fnp-3050	180	18	neurodegeneration	neurodegeneration	NOUN
fnp-3050	180	19	[	[	X
fnp-3050	180	20	106	106	NUM
fnp-3050	180	21	]	]	PUNCT
fnp-3050	180	22	.	.	PUNCT
fnp-3050	181	1	recent	recent	ADJ
fnp-3050	181	2	studies	study	NOUN
fnp-3050	181	3	support	support	VERB
fnp-3050	181	4	the	the	DET
fnp-3050	181	5	hypothesis	hypothesis	NOUN
fnp-3050	181	6	that	that	PRON
fnp-3050	181	7	tau	tau	PROPN
fnp-3050	181	8	phosphorylation	phosphorylation	NOUN
fnp-3050	181	9	at	at	ADP
fnp-3050	181	10	ser208	ser208	NOUN
fnp-3050	181	11	strongly	strongly	ADV
fnp-3050	181	12	contributes	contribute	VERB
fnp-3050	181	13	to	to	ADP
fnp-3050	181	14	unique	unique	ADJ
fnp-3050	181	15	types	type	NOUN
fnp-3050	181	16	of	of	ADP
fnp-3050	181	17	tau	tau	PROPN
fnp-3050	181	18	aggregates	aggregate	NOUN
fnp-3050	181	19	,	,	PUNCT
fnp-3050	181	20	and	and	CCONJ
fnp-3050	181	21	may	may	AUX
fnp-3050	181	22	be	be	AUX
fnp-3050	181	23	a	a	DET
fnp-3050	181	24	reliable	reliable	ADJ
fnp-3050	181	25	marker	marker	NOUN
fnp-3050	181	26	for	for	ADP
fnp-3050	181	27	the	the	DET
fnp-3050	181	28	presence	presence	NOUN
fnp-3050	181	29	of	of	ADP
fnp-3050	181	30	mature	mature	ADJ
fnp-3050	181	31	nfts	nft	NOUN
fnp-3050	181	32	[	[	X
fnp-3050	181	33	107	107	NUM
fnp-3050	181	34	]	]	PUNCT
fnp-3050	181	35	.	.	PUNCT
fnp-3050	182	1	in	in	ADP
fnp-3050	182	2	ad	ad	NOUN
fnp-3050	182	3	,	,	PUNCT
fnp-3050	182	4	tau	tau	PROPN
fnp-3050	182	5	protein	protein	NOUN
fnp-3050	182	6	usually	usually	ADV
fnp-3050	182	7	accumulates	accumulate	VERB
fnp-3050	182	8	in	in	ADP
fnp-3050	182	9	the	the	DET
fnp-3050	182	10	somato	somato	NOUN
fnp-3050	182	11	-	-	PUNCT
fnp-3050	182	12	dendritic	dendritic	ADJ
fnp-3050	182	13	and	and	CCONJ
fnp-3050	182	14	,	,	PUNCT
fnp-3050	182	15	to	to	ADP
fnp-3050	182	16	a	a	DET
fnp-3050	182	17	lesser	less	ADJ
fnp-3050	182	18	degree	degree	NOUN
fnp-3050	182	19	,	,	PUNCT
fnp-3050	182	20	in	in	ADP
fnp-3050	182	21	the	the	DET
fnp-3050	182	22	axonal	axonal	ADJ
fnp-3050	182	23	domains	domain	NOUN
fnp-3050	182	24	of	of	ADP
fnp-3050	182	25	the	the	DET
fnp-3050	182	26	neuron	neuron	PROPN
fnp-3050	182	27	.	.	PUNCT
fnp-3050	183	1	nfts	nft	NOUN
fnp-3050	183	2	and	and	CCONJ
fnp-3050	183	3	pretangles	pretangle	NOUN
fnp-3050	183	4	are	be	AUX
fnp-3050	183	5	due	due	ADJ
fnp-3050	183	6	to	to	ADP
fnp-3050	183	7	accumulation	accumulation	NOUN
fnp-3050	183	8	in	in	ADP
fnp-3050	183	9	the	the	DET
fnp-3050	183	10	soma	soma	NOUN
fnp-3050	183	11	;	;	PUNCT
fnp-3050	183	12	nts	nt	NOUN
fnp-3050	183	13	occur	occur	VERB
fnp-3050	183	14	in	in	ADP
fnp-3050	183	15	dendrites	dendrite	NOUN
fnp-3050	183	16	,	,	PUNCT
fnp-3050	183	17	and	and	CCONJ
fnp-3050	183	18	the	the	DET
fnp-3050	183	19	neuritic	neuritic	ADJ
fnp-3050	183	20	corona	corona	NOUN
fnp-3050	183	21	of	of	ADP
fnp-3050	183	22	core	core	NOUN
fnp-3050	183	23	plaques	plaque	NOUN
fnp-3050	183	24	is	be	AUX
fnp-3050	183	25	constituated	constituate	VERB
fnp-3050	183	26	by	by	ADP
fnp-3050	183	27	axonal	axonal	ADJ
fnp-3050	183	28	processes	process	NOUN
fnp-3050	183	29	filled	fill	VERB
fnp-3050	183	30	by	by	ADP
fnp-3050	183	31	tau	tau	PROPN
fnp-3050	183	32	proteins	protein	NOUN
fnp-3050	183	33	(	(	PUNCT
fnp-3050	183	34	fig	fig	NOUN
fnp-3050	183	35	.	.	PUNCT
fnp-3050	184	1	2	2	NUM
fnp-3050	184	2	)	)	PUNCT
fnp-3050	184	3	.	.	PUNCT
fnp-3050	185	1	as	as	ADP
fnp-3050	185	2	major	major	ADJ
fnp-3050	185	3	constituents	constituent	NOUN
fnp-3050	185	4	of	of	ADP
fnp-3050	185	5	nfts	nft	NOUN
fnp-3050	185	6	and	and	CCONJ
fnp-3050	185	7	nts	nt	NOUN
fnp-3050	185	8	,	,	PUNCT
fnp-3050	185	9	they	they	PRON
fnp-3050	185	10	are	be	AUX
fnp-3050	185	11	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-3050	185	12	and	and	CCONJ
fnp-3050	185	13	aberrantly	aberrantly	ADV
fnp-3050	185	14	misfolded	misfolde	VERB
fnp-3050	185	15	,	,	PUNCT
fnp-3050	185	16	have	have	AUX
fnp-3050	185	17	lost	lose	VERB
fnp-3050	185	18	their	their	PRON
fnp-3050	185	19	microtubule	microtubule	NOUN
fnp-3050	185	20	stabilizing	stabilizing	NOUN
fnp-3050	185	21	functions	function	NOUN
fnp-3050	185	22	,	,	PUNCT
fnp-3050	185	23	and	and	CCONJ
fnp-3050	185	24	contribute	contribute	VERB
fnp-3050	185	25	to	to	ADP
fnp-3050	185	26	axonal	axonal	ADJ
fnp-3050	185	27	transport	transport	NOUN
fnp-3050	185	28	deficits	deficit	NOUN
fnp-3050	185	29	[	[	X
fnp-3050	185	30	105	105	NUM
fnp-3050	185	31	]	]	PUNCT
fnp-3050	185	32	.	.	PUNCT
fnp-3050	186	1	phfs	phfs	PROPN
fnp-3050	186	2	in	in	ADP
fnp-3050	186	3	ad	ad	NOUN
fnp-3050	186	4	contain	contain	VERB
fnp-3050	186	5	all	all	DET
fnp-3050	186	6	6	6	NUM
fnp-3050	186	7	isoforms	isoform	NOUN
fnp-3050	186	8	of	of	ADP
fnp-3050	186	9	tau	tau	PROPN
fnp-3050	186	10	protein	protein	NOUN
fnp-3050	186	11	including	include	VERB
fnp-3050	186	12	those	those	PRON
fnp-3050	186	13	with	with	ADP
fnp-3050	186	14	3	3	NUM
fnp-3050	186	15	and	and	CCONJ
fnp-3050	186	16	4	4	NUM
fnp-3050	186	17	repeats	repeat	NOUN
fnp-3050	186	18	(	(	PUNCT
fnp-3050	186	19	3rand	3rand	NUM
fnp-3050	186	20	4r	4r	NUM
fnp-3050	186	21	-	-	PUNCT
fnp-3050	186	22	tau	tau	NOUN
fnp-3050	186	23	)	)	PUNCT
fnp-3050	186	24	in	in	ADP
fnp-3050	186	25	the	the	DET
fnp-3050	186	26	microtubule	microtubule	NOUN
fnp-3050	186	27	binding	bind	VERB
fnp-3050	186	28	domain	domain	NOUN
fnp-3050	186	29	,	,	PUNCT
fnp-3050	186	30	forming	form	VERB
fnp-3050	186	31	the	the	DET
fnp-3050	186	32	core	core	NOUN
fnp-3050	186	33	of	of	ADP
fnp-3050	186	34	phf	phf	NOUN
fnp-3050	186	35	[	[	X
fnp-3050	186	36	108	108	NUM
fnp-3050	186	37	]	]	PUNCT
fnp-3050	186	38	.	.	PUNCT
fnp-3050	187	1	the	the	DET
fnp-3050	187	2	tau	tau	PROPN
fnp-3050	187	3	isoforms	isoform	NOUN
fnp-3050	187	4	show	show	VERB
fnp-3050	187	5	a	a	DET
fnp-3050	187	6	chronological	chronological	ADJ
fnp-3050	187	7	shift	shift	NOUN
fnp-3050	187	8	:	:	PUNCT
fnp-3050	187	9	initially	initially	ADV
fnp-3050	187	10	,	,	PUNCT
fnp-3050	187	11	early	early	ADJ
fnp-3050	187	12	pretangles	pretangle	NOUN
fnp-3050	187	13	are	be	AUX
fnp-3050	187	14	positive	positive	ADJ
fnp-3050	187	15	only	only	ADV
fnp-3050	187	16	for	for	ADP
fnp-3050	187	17	4r	4r	NOUN
fnp-3050	187	18	,	,	PUNCT
fnp-3050	187	19	gradually	gradually	ADV
fnp-3050	187	20	3r	3r	NUM
fnp-3050	187	21	is	be	AUX
fnp-3050	187	22	involved	involve	VERB
fnp-3050	187	23	in	in	ADP
fnp-3050	187	24	mature	mature	ADJ
fnp-3050	187	25	tangles	tangle	NOUN
fnp-3050	187	26	,	,	PUNCT
fnp-3050	187	27	and	and	CCONJ
fnp-3050	187	28	finally	finally	ADV
fnp-3050	187	29	4r	4r	NUM
fnp-3050	187	30	is	be	AUX
fnp-3050	187	31	replaced	replace	VERB
fnp-3050	187	32	by	by	ADP
fnp-3050	187	33	3r	3r	NUM
fnp-3050	187	34	in	in	ADP
fnp-3050	187	35	ghost	ghost	NOUN
fnp-3050	187	36	tangles	tangle	NOUN
fnp-3050	187	37	[	[	X
fnp-3050	187	38	109	109	NUM
fnp-3050	187	39	]	]	PUNCT
fnp-3050	187	40	.	.	PUNCT
fnp-3050	188	1	ultrastructurally	ultrastructurally	ADV
fnp-3050	188	2	,	,	PUNCT
fnp-3050	188	3	nfts	nft	NOUN
fnp-3050	188	4	appear	appear	VERB
fnp-3050	188	5	as	as	ADP
fnp-3050	188	6	phfs	phfs	ADJ
fnp-3050	188	7	,	,	PUNCT
fnp-3050	188	8	i.e.	i.e.	X
fnp-3050	188	9	,	,	PUNCT
fnp-3050	188	10	fibrils	fibril	NOUN
fnp-3050	188	11	of	of	ADP
fnp-3050	188	12	ca	ca	PROPN
fnp-3050	188	13	.	.	PUNCT
fnp-3050	189	1	28	28	NUM
fnp-3050	189	2	nm	nm	NOUN
fnp-3050	189	3	in	in	ADP
fnp-3050	189	4	diameter	diameter	NOUN
fnp-3050	189	5	that	that	PRON
fnp-3050	189	6	form	form	VERB
fnp-3050	189	7	pairs	pair	NOUN
fnp-3050	189	8	with	with	ADP
fnp-3050	189	9	a	a	DET
fnp-3050	189	10	helical	helical	ADJ
fnp-3050	189	11	tridimensional	tridimensional	ADJ
fnp-3050	189	12	conformation	conformation	NOUN
fnp-3050	189	13	and	and	CCONJ
fnp-3050	189	14	a	a	DET
fnp-3050	189	15	regular	regular	ADJ
fnp-3050	189	16	periodicity	periodicity	NOUN
fnp-3050	189	17	of	of	ADP
fnp-3050	189	18	65	65	NUM
fnp-3050	189	19	-	-	SYM
fnp-3050	189	20	80	80	NUM
fnp-3050	189	21	nm	nm	NOUN
fnp-3050	190	1	[	[	X
fnp-3050	190	2	110	110	NUM
fnp-3050	190	3	]	]	PUNCT
fnp-3050	190	4	or	or	CCONJ
fnp-3050	190	5	as	as	ADP
fnp-3050	190	6	helical	helical	ADJ
fnp-3050	190	7	or	or	CCONJ
fnp-3050	190	8	twisted	twisted	ADJ
fnp-3050	190	9	ribbons	ribbon	NOUN
fnp-3050	190	10	[	[	X
fnp-3050	190	11	111	111	NUM
fnp-3050	190	12	]	]	PUNCT
fnp-3050	190	13	.	.	PUNCT
fnp-3050	191	1	straight	straight	ADJ
fnp-3050	191	2	filaments	filament	NOUN
fnp-3050	191	3	(	(	PUNCT
fnp-3050	191	4	sfs	sfs	ADJ
fnp-3050	191	5	)	)	PUNCT
fnp-3050	191	6	show	show	VERB
fnp-3050	191	7	a	a	PRON
fnp-3050	191	8	longer	long	ADJ
fnp-3050	191	9	crossover	crossover	VERB
fnp-3050	191	10	distance	distance	NOUN
fnp-3050	191	11	and	and	CCONJ
fnp-3050	191	12	modulations	modulation	NOUN
fnp-3050	191	13	in	in	ADP
fnp-3050	191	14	width	width	NOUN
fnp-3050	191	15	from	from	ADP
fnp-3050	191	16	10	10	NUM
fnp-3050	191	17	to	to	PART
fnp-3050	191	18	15	15	NUM
fnp-3050	191	19	nm	nm	NOUN
fnp-3050	191	20	.	.	PUNCT
fnp-3050	192	1	both	both	DET
fnp-3050	192	2	lesions	lesion	NOUN
fnp-3050	192	3	are	be	AUX
fnp-3050	192	4	different	different	ADJ
fnp-3050	192	5	from	from	ADP
fnp-3050	192	6	those	those	PRON
fnp-3050	192	7	seen	see	VERB
fnp-3050	192	8	in	in	ADP
fnp-3050	192	9	other	other	ADJ
fnp-3050	192	10	tauopathies	tauopathie	NOUN
fnp-3050	192	11	[	[	X
fnp-3050	192	12	112	112	NUM
fnp-3050	192	13	]	]	PUNCT
fnp-3050	192	14	.	.	PUNCT
fnp-3050	193	1	phfs	phfs	PROPN
fnp-3050	193	2	and	and	CCONJ
fnp-3050	193	3	sfs	sfs	PROPN
fnp-3050	193	4	differ	differ	VERB
fnp-3050	193	5	in	in	ADP
fnp-3050	193	6	their	their	PRON
fnp-3050	193	7	inter	inter	ADJ
fnp-3050	193	8	-	-	ADJ
fnp-3050	193	9	protofilament	protofilament	ADJ
fnp-3050	193	10	packing	packing	NOUN
fnp-3050	193	11	,	,	PUNCT
fnp-3050	193	12	and	and	CCONJ
fnp-3050	193	13	are	be	AUX
fnp-3050	193	14	ultrastructurally	ultrastructurally	ADV
fnp-3050	193	15	polymorph	polymorph	NOUN
fnp-3050	193	16	[	[	X
fnp-3050	193	17	113	113	NUM
fnp-3050	193	18	]	]	PUNCT
fnp-3050	193	19	.	.	PUNCT
fnp-3050	194	1	visible	visible	ADJ
fnp-3050	194	2	with	with	ADP
fnp-3050	194	3	cryo	cryo	NOUN
fnp-3050	194	4	-	-	PUNCT
fnp-3050	194	5	em	em	PROPN
fnp-3050	194	6	,	,	PUNCT
fnp-3050	194	7	phfs	phfs	ADJ
fnp-3050	194	8	and	and	CCONJ
fnp-3050	194	9	sfs	sfs	NOUN
fnp-3050	194	10	are	be	AUX
fnp-3050	194	11	made	make	VERB
fnp-3050	194	12	of	of	ADP
fnp-3050	194	13	two	two	NUM
fnp-3050	194	14	c	c	ADV
fnp-3050	194	15	-	-	PUNCT
fnp-3050	194	16	shaped	shape	VERB
fnp-3050	194	17	protofilaments	protofilament	NOUN
fnp-3050	194	18	with	with	ADP
fnp-3050	194	19	a	a	DET
fnp-3050	194	20	combined	combined	ADJ
fnp-3050	194	21	cross	cross	NOUN
fnp-3050	194	22	-	-	ADJ
fnp-3050	194	23	β	β	ADJ
fnp-3050	194	24	-	-	ADJ
fnp-3050	194	25	β	β	NOUN
fnp-3050	194	26	-	-	PUNCT
fnp-3050	194	27	helix	helix	ADJ
fnp-3050	194	28	structure	structure	NOUN
fnp-3050	194	29	,	,	PUNCT
fnp-3050	194	30	without	without	ADP
fnp-3050	194	31	variations	variation	NOUN
fnp-3050	194	32	in	in	ADP
fnp-3050	194	33	the	the	DET
fnp-3050	194	34	filamentous	filamentous	ADJ
fnp-3050	194	35	structures	structure	NOUN
fnp-3050	194	36	between	between	ADP
fnp-3050	194	37	sporadic	sporadic	ADJ
fnp-3050	194	38	and	and	CCONJ
fnp-3050	194	39	inherited	inherit	VERB
fnp-3050	194	40	ad	ad	NOUN
fnp-3050	194	41	[	[	X
fnp-3050	194	42	114	114	NUM
fnp-3050	194	43	]	]	PUNCT
fnp-3050	194	44	.	.	PUNCT
fnp-3050	195	1	nts	nt	NOUN
fnp-3050	195	2	have	have	VERB
fnp-3050	195	3	an	an	DET
fnp-3050	195	4	ultrastructure	ultrastructure	NOUN
fnp-3050	195	5	and	and	CCONJ
fnp-3050	195	6	immunohistochemistry	immunohistochemistry	NOUN
fnp-3050	195	7	similar	similar	ADJ
fnp-3050	195	8	to	to	ADP
fnp-3050	195	9	nfts	nft	NOUN
fnp-3050	195	10	.	.	PUNCT
fnp-3050	196	1	why	why	SCONJ
fnp-3050	196	2	,	,	PUNCT
fnp-3050	196	3	despite	despite	SCONJ
fnp-3050	196	4	its	its	PRON
fnp-3050	196	5	axonal	axonal	ADJ
fnp-3050	196	6	origin	origin	NOUN
fnp-3050	196	7	,	,	PUNCT
fnp-3050	196	8	phf	phf	PROPN
fnp-3050	196	9	tau	tau	PROPN
fnp-3050	196	10	accumulates	accumulate	VERB
fnp-3050	196	11	primarily	primarily	ADV
fnp-3050	196	12	in	in	ADP
fnp-3050	196	13	the	the	DET
fnp-3050	196	14	neuronal	neuronal	ADJ
fnp-3050	196	15	cell	cell	NOUN
fnp-3050	196	16	body	body	NOUN
fnp-3050	196	17	and	and	CCONJ
fnp-3050	196	18	dendrites	dendrite	NOUN
fnp-3050	196	19	,	,	PUNCT
fnp-3050	196	20	is	be	AUX
fnp-3050	196	21	unknown	unknown	ADJ
fnp-3050	196	22	.	.	PUNCT
fnp-3050	197	1	it	it	PRON
fnp-3050	197	2	shows	show	VERB
fnp-3050	197	3	in	in	ADP
fnp-3050	197	4	three	three	NUM
fnp-3050	197	5	stages	stage	NOUN
fnp-3050	197	6	:	:	PUNCT
fnp-3050	197	7	(	(	PUNCT
fnp-3050	197	8	a	a	X
fnp-3050	197	9	)	)	PUNCT
fnp-3050	197	10	pre	pre	ADJ
fnp-3050	197	11	-	-	ADJ
fnp-3050	197	12	nfts	nft	NOUN
fnp-3050	197	13	composed	compose	VERB
fnp-3050	197	14	of	of	ADP
fnp-3050	197	15	diffuse	diffuse	NOUN
fnp-3050	197	16	,	,	PUNCT
fnp-3050	197	17	or	or	CCONJ
fnp-3050	197	18	punctuate	punctuate	VERB
fnp-3050	197	19	tau	tau	PROPN
fnp-3050	197	20	staining	stain	VERB
fnp-3050	197	21	occur	occur	VERB
fnp-3050	197	22	within	within	ADP
fnp-3050	197	23	the	the	DET
fnp-3050	197	24	cytoplasm	cytoplasm	NOUN
fnp-3050	197	25	of	of	ADP
fnp-3050	197	26	otherwise	otherwise	ADV
fnp-3050	197	27	normal	normal	ADJ
fnp-3050	197	28	-	-	PUNCT
fnp-3050	197	29	looking	look	VERB
fnp-3050	197	30	neurons	neuron	NOUN
fnp-3050	197	31	with	with	ADP
fnp-3050	197	32	well	well	ADV
fnp-3050	197	33	-	-	PUNCT
fnp-3050	197	34	preserved	preserve	VERB
fnp-3050	197	35	neurites	neurite	NOUN
fnp-3050	197	36	;	;	PUNCT
fnp-3050	197	37	or	or	CCONJ
fnp-3050	197	38	(	(	PUNCT
fnp-3050	197	39	b	b	X
fnp-3050	197	40	)	)	PUNCT
fnp-3050	197	41	mature	mature	ADJ
fnp-3050	197	42	intraneuronal	intraneuronal	ADJ
fnp-3050	197	43	nfts	nft	NOUN
fnp-3050	197	44	consist	consist	VERB
fnp-3050	197	45	of	of	ADP
fnp-3050	197	46	cytoplasmic	cytoplasmic	ADJ
fnp-3050	197	47	filamentous	filamentous	ADJ
fnp-3050	197	48	aggregates	aggregate	NOUN
fnp-3050	197	49	of	of	ADP
fnp-3050	197	50	tau	tau	PROPN
fnp-3050	197	51	displacing	displace	VERB
fnp-3050	197	52	the	the	DET
fnp-3050	197	53	nucleus	nucleus	NOUN
fnp-3050	197	54	toward	toward	ADP
fnp-3050	197	55	the	the	DET
fnp-3050	197	56	periphery	periphery	NOUN
fnp-3050	197	57	of	of	ADP
fnp-3050	197	58	the	the	DET
fnp-3050	197	59	soma	soma	NOUN
fnp-3050	197	60	and	and	CCONJ
fnp-3050	197	61	extending	extend	VERB
fnp-3050	197	62	to	to	ADP
fnp-3050	197	63	the	the	DET
fnp-3050	197	64	proximal	proximal	ADJ
fnp-3050	197	65	segment	segment	NOUN
fnp-3050	197	66	of	of	ADP
fnp-3050	197	67	the	the	DET
fnp-3050	197	68	axon	axon	NOUN
fnp-3050	197	69	.	.	PUNCT
fnp-3050	198	1	they	they	PRON
fnp-3050	198	2	appear	appear	VERB
fnp-3050	198	3	as	as	ADP
fnp-3050	198	4	“	"	PUNCT
fnp-3050	198	5	flame	flame	NOUN
fnp-3050	198	6	-	-	PUNCT
fnp-3050	198	7	shaped	shape	VERB
fnp-3050	198	8	tangles	tangle	NOUN
fnp-3050	198	9	”	"	PUNCT
fnp-3050	198	10	in	in	ADP
fnp-3050	198	11	pyramidal	pyramidal	ADJ
fnp-3050	198	12	neurons	neuron	NOUN
fnp-3050	198	13	of	of	ADP
fnp-3050	198	14	the	the	DET
fnp-3050	198	15	hippocampus	hippocampus	NOUN
fnp-3050	198	16	(	(	PUNCT
fnp-3050	198	17	fig	fig	NOUN
fnp-3050	198	18	.	.	PUNCT
fnp-3050	199	1	5	5	NUM
fnp-3050	199	2	)	)	PUNCT
fnp-3050	200	1	and	and	CCONJ
fnp-3050	200	2	layer	layer	NOUN
fnp-3050	200	3	v	v	NOUN
fnp-3050	200	4	of	of	ADP
fnp-3050	200	5	association	association	NOUN
fnp-3050	200	6	cortices	cortex	NOUN
fnp-3050	200	7	and	and	CCONJ
fnp-3050	200	8	as	as	ADP
fnp-3050	200	9	“	"	PUNCT
fnp-3050	200	10	globose	globose	NOUN
fnp-3050	200	11	tangles	tangle	NOUN
fnp-3050	200	12	”	"	PUNCT
fnp-3050	200	13	in	in	ADP
fnp-3050	200	14	subcortical	subcortical	ADJ
fnp-3050	200	15	nuclei	nucleus	NOUN
fnp-3050	200	16	;	;	PUNCT
fnp-3050	200	17	(	(	PUNCT
fnp-3050	200	18	c	c	X
fnp-3050	200	19	)	)	PUNCT
fnp-3050	200	20	extraneuronal	extraneuronal	ADJ
fnp-3050	200	21	“	"	PUNCT
fnp-3050	200	22	ghost	ghost	NOUN
fnp-3050	200	23	”	"	PUNCT
fnp-3050	200	24	nfts	nft	NOUN
fnp-3050	200	25	in	in	ADP
fnp-3050	200	26	dead	dead	ADJ
fnp-3050	200	27	neurons	neuron	NOUN
fnp-3050	200	28	,	,	PUNCT
fnp-3050	200	29	showing	show	VERB
fnp-3050	200	30	loss	loss	NOUN
fnp-3050	200	31	of	of	ADP
fnp-3050	200	32	their	their	PRON
fnp-3050	200	33	nucleus	nucleus	NOUN
fnp-3050	200	34	and	and	CCONJ
fnp-3050	200	35	of	of	ADP
fnp-3050	200	36	stainable	stainable	ADJ
fnp-3050	200	37	cytoplasm	cytoplasm	NOUN
fnp-3050	200	38	[	[	X
fnp-3050	200	39	115	115	NUM
fnp-3050	200	40	]	]	PUNCT
fnp-3050	200	41	.	.	PUNCT
fnp-3050	201	1	total	total	ADJ
fnp-3050	201	2	loss	loss	NOUN
fnp-3050	201	3	of	of	ADP
fnp-3050	201	4	functional	functional	ADJ
fnp-3050	201	5	microglia	microglia	NOUN
fnp-3050	201	6	in	in	ADP
fnp-3050	201	7	advanced	advanced	ADJ
fnp-3050	201	8	late	late	ADJ
fnp-3050	201	9	-	-	PUNCT
fnp-3050	201	10	onset	onset	NOUN
fnp-3050	201	11	ad	ad	NOUN
fnp-3050	201	12	(	(	PUNCT
fnp-3050	201	13	load	load	NOUN
fnp-3050	201	14	)	)	PUNCT
fnp-3050	201	15	promotes	promote	VERB
fnp-3050	201	16	widespread	widespread	ADJ
fnp-3050	201	17	intraneuronal	intraneuronal	ADJ
fnp-3050	201	18	neurofibrillary	neurofibrillary	ADJ
fnp-3050	201	19	degeneration	degeneration	NOUN
fnp-3050	201	20	leading	lead	VERB
fnp-3050	201	21	to	to	ADP
fnp-3050	201	22	brain	brain	NOUN
fnp-3050	201	23	failure	failure	NOUN
fnp-3050	201	24	[	[	X
fnp-3050	201	25	116	116	NUM
fnp-3050	201	26	]	]	PUNCT
fnp-3050	201	27	.	.	PUNCT
fnp-3050	202	1	neuronal	neuronal	ADJ
fnp-3050	202	2	tau	tau	PROPN
fnp-3050	202	3	pathology	pathology	NOUN
fnp-3050	202	4	has	have	AUX
fnp-3050	202	5	been	be	AUX
fnp-3050	202	6	linked	link	VERB
fnp-3050	202	7	to	to	ADP
fnp-3050	202	8	neuronal	neuronal	ADJ
fnp-3050	202	9	death	death	NOUN
fnp-3050	202	10	and	and	CCONJ
fnp-3050	202	11	cognitive	cognitive	ADJ
fnp-3050	202	12	decline	decline	NOUN
fnp-3050	202	13	in	in	ADP
fnp-3050	202	14	ad	ad	NOUN
fnp-3050	202	15	[	[	X
fnp-3050	202	16	117	117	NUM
fnp-3050	202	17	]	]	PUNCT
fnp-3050	202	18	,	,	PUNCT
fnp-3050	202	19	while	while	SCONJ
fnp-3050	202	20	others	other	NOUN
fnp-3050	202	21	suggested	suggest	VERB
fnp-3050	202	22	that	that	SCONJ
fnp-3050	202	23	neuronal	neuronal	ADJ
fnp-3050	202	24	cell	cell	NOUN
fnp-3050	202	25	loss	loss	NOUN
fnp-3050	202	26	is	be	AUX
fnp-3050	202	27	associated	associate	VERB
fnp-3050	202	28	with	with	ADP
fnp-3050	202	29	dementia	dementia	NOUN
fnp-3050	202	30	and	and	CCONJ
fnp-3050	202	31	not	not	PART
fnp-3050	202	32	the	the	DET
fnp-3050	202	33	presence	presence	NOUN
fnp-3050	202	34	of	of	ADP
fnp-3050	202	35	plaques	plaque	NOUN
fnp-3050	202	36	and	and	CCONJ
fnp-3050	202	37	tangles	tangle	NOUN
fnp-3050	203	1	[	[	X
fnp-3050	203	2	118	118	NUM
fnp-3050	203	3	]	]	PUNCT
fnp-3050	203	4	.	.	PUNCT
fnp-3050	204	1	it	it	PRON
fnp-3050	204	2	is	be	AUX
fnp-3050	204	3	generally	generally	ADV
fnp-3050	204	4	thought	think	VERB
fnp-3050	204	5	that	that	SCONJ
fnp-3050	204	6	nfts	nft	NOUN
fnp-3050	204	7	impede	impede	VERB
fnp-3050	204	8	neuronal	neuronal	ADJ
fnp-3050	204	9	functioning	functioning	NOUN
fnp-3050	204	10	,	,	PUNCT
fnp-3050	204	11	but	but	CCONJ
fnp-3050	204	12	recent	recent	ADJ
fnp-3050	204	13	data	datum	NOUN
fnp-3050	204	14	indicate	indicate	VERB
fnp-3050	204	15	that	that	SCONJ
fnp-3050	204	16	they	they	PRON
fnp-3050	204	17	can	can	AUX
fnp-3050	204	18	be	be	AUX
fnp-3050	204	19	found	find	VERB
fnp-3050	204	20	in	in	ADP
fnp-3050	204	21	functionally	functionally	ADV
fnp-3050	204	22	intact	intact	ADJ
fnp-3050	204	23	neurons	neuron	NOUN
fnp-3050	204	24	integrated	integrate	VERB
fnp-3050	204	25	in	in	ADP
fnp-3050	204	26	cortical	cortical	ADJ
fnp-3050	204	27	circuits	circuit	NOUN
fnp-3050	204	28	[	[	X
fnp-3050	204	29	119	119	NUM
fnp-3050	204	30	-	-	SYM
fnp-3050	204	31	121	121	NUM
fnp-3050	204	32	]	]	PUNCT
fnp-3050	204	33	.	.	PUNCT
fnp-3050	205	1	how	how	SCONJ
fnp-3050	205	2	hp	hp	VERB
fnp-3050	205	3	-	-	ADJ
fnp-3050	205	4	tau	tau	PROPN
fnp-3050	205	5	specifically	specifically	ADV
fnp-3050	205	6	mediates	mediate	VERB
fnp-3050	205	7	its	its	PRON
fnp-3050	205	8	toxic	toxic	ADJ
fnp-3050	205	9	effects	effect	NOUN
fnp-3050	205	10	is	be	AUX
fnp-3050	205	11	still	still	ADV
fnp-3050	205	12	unknown	unknown	ADJ
fnp-3050	205	13	,	,	PUNCT
fnp-3050	205	14	but	but	CCONJ
fnp-3050	205	15	oligomeric	oligomeric	ADJ
fnp-3050	205	16	tau	tau	PROPN
fnp-3050	205	17	species	specie	NOUN
fnp-3050	205	18	,	,	PUNCT
fnp-3050	205	19	analogues	analogue	NOUN
fnp-3050	205	20	to	to	ADP
fnp-3050	205	21	aβos	aβos	PROPN
fnp-3050	205	22	,	,	PUNCT
fnp-3050	205	23	are	be	AUX
fnp-3050	205	24	potential	potential	ADJ
fnp-3050	205	25	toxic	toxic	ADJ
fnp-3050	205	26	species	specie	NOUN
fnp-3050	205	27	besides	besides	SCONJ
fnp-3050	205	28	nft	nft	PROPN
fnp-3050	205	29	tau	tau	PROPN
fnp-3050	205	30	.	.	PUNCT
fnp-3050	206	1	recent	recent	ADJ
fnp-3050	206	2	proteomic	proteomic	ADJ
fnp-3050	206	3	studies	study	NOUN
fnp-3050	206	4	have	have	AUX
fnp-3050	206	5	identified	identify	VERB
fnp-3050	206	6	specific	specific	ADJ
fnp-3050	206	7	proteins	protein	NOUN
fnp-3050	206	8	that	that	PRON
fnp-3050	206	9	interact	interact	VERB
fnp-3050	206	10	with	with	ADP
fnp-3050	206	11	hp	hp	PROPN
fnp-3050	206	12	-	-	PUNCT
fnp-3050	206	13	tau	tau	NOUN
fnp-3050	206	14	,	,	PUNCT
fnp-3050	206	15	showing	show	VERB
fnp-3050	206	16	novel	novel	ADJ
fnp-3050	206	17	potential	potential	ADJ
fnp-3050	206	18	pathogenic	pathogenic	ADJ
fnp-3050	206	19	mechanisms	mechanism	NOUN
fnp-3050	206	20	that	that	PRON
fnp-3050	206	21	are	be	AUX
fnp-3050	206	22	relevant	relevant	ADJ
fnp-3050	206	23	in	in	ADP
fnp-3050	206	24	ad	ad	NOUN
fnp-3050	206	25	and	and	CCONJ
fnp-3050	206	26	providing	provide	VERB
fnp-3050	206	27	insight	insight	NOUN
fnp-3050	206	28	into	into	ADP
fnp-3050	206	29	how	how	SCONJ
fnp-3050	206	30	hp	hp	VERB
fnp-3050	206	31	-	-	PUNCT
fnp-3050	206	32	tau	tau	NOUN
fnp-3050	206	33	mediates	mediate	VERB
fnp-3050	206	34	its	its	PRON
fnp-3050	206	35	toxicity	toxicity	NOUN
fnp-3050	206	36	in	in	ADP
fnp-3050	206	37	ad	ad	NOUN
fnp-3050	206	38	[	[	X
fnp-3050	206	39	122	122	NUM
fnp-3050	206	40	]	]	PUNCT
fnp-3050	206	41	.	.	PUNCT
fnp-3050	207	1	figure	figure	NOUN
fnp-3050	207	2	5	5	NUM
fnp-3050	207	3	.	.	PUNCT
fnp-3050	208	1	in	in	ADP
fnp-3050	208	2	ad	ad	NOUN
fnp-3050	208	3	,	,	PUNCT
fnp-3050	208	4	high	high	ADJ
fnp-3050	208	5	amounts	amount	NOUN
fnp-3050	208	6	of	of	ADP
fnp-3050	208	7	neurofibrillary	neurofibrillary	ADJ
fnp-3050	208	8	tangles	tangle	NOUN
fnp-3050	208	9	and	and	CCONJ
fnp-3050	208	10	neuropil	neuropil	NOUN
fnp-3050	208	11	threads	thread	NOUN
fnp-3050	208	12	are	be	AUX
fnp-3050	208	13	seen	see	VERB
fnp-3050	208	14	in	in	ADP
fnp-3050	208	15	the	the	DET
fnp-3050	208	16	hippocampus	hippocampus	NOUN
fnp-3050	208	17	(	(	PUNCT
fnp-3050	208	18	a	a	NOUN
fnp-3050	208	19	)	)	PUNCT
fnp-3050	208	20	.	.	PUNCT
fnp-3050	209	1	ca1	ca1	PROPN
fnp-3050	209	2	,	,	PUNCT
fnp-3050	209	3	ca2	ca2	PROPN
fnp-3050	209	4	,	,	PUNCT
fnp-3050	209	5	and	and	CCONJ
fnp-3050	209	6	ca4	ca4	NOUN
fnp-3050	209	7	hippocampal	hippocampal	ADJ
fnp-3050	209	8	cornu	cornu	NOUN
fnp-3050	209	9	ammonis	ammonis	PROPN
fnp-3050	209	10	(	(	PUNCT
fnp-3050	209	11	ammon	ammon	PROPN
fnp-3050	209	12	’s	’s	PART
fnp-3050	209	13	horn	horn	NOUN
fnp-3050	209	14	)	)	PUNCT
fnp-3050	209	15	sectors	sector	NOUN
fnp-3050	209	16	1	1	NUM
fnp-3050	209	17	,	,	PUNCT
fnp-3050	209	18	2	2	NUM
fnp-3050	209	19	,	,	PUNCT
fnp-3050	209	20	and	and	CCONJ
fnp-3050	209	21	3	3	NUM
fnp-3050	209	22	,	,	PUNCT
fnp-3050	209	23	respectively	respectively	ADV
fnp-3050	209	24	;	;	PUNCT
fnp-3050	209	25	gr	gr	NUM
fnp-3050	209	26	,	,	PUNCT
fnp-3050	209	27	granule	granule	NOUN
fnp-3050	209	28	cell	cell	NOUN
fnp-3050	209	29	layer	layer	NOUN
fnp-3050	209	30	of	of	ADP
fnp-3050	209	31	the	the	DET
fnp-3050	209	32	dentate	dentate	ADJ
fnp-3050	209	33	gyrus	gyrus	NOUN
fnp-3050	209	34	.	.	PUNCT
fnp-3050	210	1	immunohistochemistry	immunohistochemistry	NOUN
fnp-3050	210	2	with	with	ADP
fnp-3050	210	3	antibody	antibody	NOUN
fnp-3050	210	4	at8	at8	PROPN
fnp-3050	210	5	.	.	PUNCT
fnp-3050	211	1	scale	scale	NOUN
fnp-3050	211	2	bar	bar	NOUN
fnp-3050	211	3	:	:	PUNCT
fnp-3050	211	4	50	50	NUM
fnp-3050	211	5	μm	μm	NOUN
fnp-3050	211	6	.	.	PUNCT
fnp-3050	211	7	from	from	ADP
fnp-3050	211	8	[	[	X
fnp-3050	211	9	71	71	NUM
fnp-3050	211	10	]	]	PUNCT
fnp-3050	211	11	.	.	PUNCT
fnp-3050	212	1	2.7	2.7	NUM
fnp-3050	212	2	.	.	PUNCT
fnp-3050	212	3	topography	topography	NOUN
fnp-3050	212	4	and	and	CCONJ
fnp-3050	212	5	spreading	spread	VERB
fnp-3050	212	6	pattern	pattern	NOUN
fnp-3050	212	7	of	of	ADP
fnp-3050	212	8	tau	tau	PROPN
fnp-3050	212	9	the	the	DET
fnp-3050	212	10	extent	extent	NOUN
fnp-3050	212	11	of	of	ADP
fnp-3050	212	12	tau	tau	PROPN
fnp-3050	212	13	pathology	pathology	NOUN
fnp-3050	212	14	(	(	PUNCT
fnp-3050	212	15	nfts	nft	NOUN
fnp-3050	212	16	and	and	CCONJ
fnp-3050	212	17	nts	nt	NOUN
fnp-3050	212	18	)	)	PUNCT
fnp-3050	212	19	follows	follow	VERB
fnp-3050	212	20	a	a	DET
fnp-3050	212	21	predictable	predictable	ADJ
fnp-3050	212	22	spatiotemporal	spatiotemporal	ADJ
fnp-3050	212	23	progression	progression	NOUN
fnp-3050	212	24	through	through	ADP
fnp-3050	212	25	functionally	functionally	ADV
fnp-3050	212	26	integrated	integrate	VERB
fnp-3050	212	27	brain	brain	NOUN
fnp-3050	212	28	regions	region	NOUN
fnp-3050	212	29	[	[	X
fnp-3050	212	30	18	18	NUM
fnp-3050	212	31	]	]	PUNCT
fnp-3050	212	32	,	,	PUNCT
fnp-3050	212	33	which	which	PRON
fnp-3050	212	34	had	have	AUX
fnp-3050	212	35	been	be	AUX
fnp-3050	212	36	interpreted	interpret	VERB
fnp-3050	212	37	as	as	ADP
fnp-3050	212	38	a	a	DET
fnp-3050	212	39	cell	cell	NOUN
fnp-3050	212	40	-	-	PUNCT
fnp-3050	212	41	to	to	ADP
fnp-3050	212	42	-	-	PUNCT
fnp-3050	212	43	cell	cell	NOUN
fnp-3050	212	44	spreading	spread	VERB
fnp-3050	212	45	through	through	ADP
fnp-3050	212	46	prion	prion	NOUN
fnp-3050	212	47	-	-	PUNCT
fnp-3050	212	48	like	like	ADJ
fnp-3050	212	49	propagation	propagation	NOUN
fnp-3050	212	50	[	[	X
fnp-3050	212	51	123	123	NUM
fnp-3050	212	52	-	-	SYM
fnp-3050	212	53	127	127	NUM
fnp-3050	212	54	]	]	PUNCT
fnp-3050	212	55	or	or	CCONJ
fnp-3050	212	56	a	a	DET
fnp-3050	212	57	transneuronal	transneuronal	ADJ
fnp-3050	212	58	spread	spread	NOUN
fnp-3050	212	59	through	through	ADP
fnp-3050	212	60	functional	functional	ADJ
fnp-3050	212	61	networks	network	NOUN
fnp-3050	212	62	,	,	PUNCT
fnp-3050	212	63	associated	associate	VERB
fnp-3050	212	64	with	with	ADP
fnp-3050	212	65	a	a	DET
fnp-3050	212	66	trigger	trigger	NOUN
fnp-3050	212	67	,	,	PUNCT
fnp-3050	212	68	possibly	possibly	ADV
fnp-3050	212	69	aβ	aβ	ADP
fnp-3050	212	70	and/or	and/or	CCONJ
fnp-3050	212	71	neuronal	neuronal	ADJ
fnp-3050	212	72	network	network	NOUN
fnp-3050	212	73	activity	activity	NOUN
fnp-3050	212	74	that	that	PRON
fnp-3050	212	75	could	could	AUX
fnp-3050	212	76	lead	lead	VERB
fnp-3050	212	77	to	to	ADP
fnp-3050	212	78	progression	progression	NOUN
fnp-3050	212	79	of	of	ADP
fnp-3050	212	80	nft	nft	PROPN
fnp-3050	212	81	pathology	pathology	PROPN
fnp-3050	213	1	[	[	X
fnp-3050	213	2	128	128	NUM
fnp-3050	213	3	]	]	PUNCT
fnp-3050	213	4	.	.	PUNCT
fnp-3050	214	1	since	since	SCONJ
fnp-3050	214	2	tau	tau	PROPN
fnp-3050	214	3	is	be	AUX
fnp-3050	214	4	expressed	express	VERB
fnp-3050	214	5	predominantly	predominantly	ADV
fnp-3050	214	6	in	in	ADP
fnp-3050	214	7	neurons	neuron	NOUN
fnp-3050	214	8	rather	rather	ADV
fnp-3050	214	9	than	than	ADP
fnp-3050	214	10	glial	glial	ADJ
fnp-3050	214	11	cells	cell	NOUN
fnp-3050	214	12	,	,	PUNCT
fnp-3050	214	13	the	the	DET
fnp-3050	214	14	detection	detection	NOUN
fnp-3050	214	15	of	of	ADP
fnp-3050	214	16	tau	tau	PROPN
fnp-3050	214	17	aggregates	aggregate	NOUN
fnp-3050	214	18	in	in	ADP
fnp-3050	214	19	astrocytes	astrocyte	NOUN
fnp-3050	214	20	and	and	CCONJ
fnp-3050	214	21	oligodendroglia	oligodendroglia	NOUN
fnp-3050	214	22	has	have	AUX
fnp-3050	214	23	given	give	VERB
fnp-3050	214	24	support	support	NOUN
fnp-3050	214	25	to	to	ADP
fnp-3050	214	26	the	the	DET
fnp-3050	214	27	concept	concept	NOUN
fnp-3050	214	28	that	that	SCONJ
fnp-3050	214	29	the	the	DET
fnp-3050	214	30	release	release	NOUN
fnp-3050	214	31	of	of	ADP
fnp-3050	214	32	misfolded	misfolde	VERB
fnp-3050	214	33	tau	tau	PROPN
fnp-3050	214	34	from	from	ADP
fnp-3050	214	35	neurons	neuron	NOUN
fnp-3050	214	36	(	(	PUNCT
fnp-3050	214	37	or	or	CCONJ
fnp-3050	214	38	oligodendroglia	oligodendroglia	NOUN
fnp-3050	214	39	)	)	PUNCT
fnp-3050	214	40	may	may	AUX
fnp-3050	214	41	result	result	VERB
fnp-3050	214	42	in	in	ADP
fnp-3050	214	43	uptake	uptake	NOUN
fnp-3050	214	44	into	into	ADP
fnp-3050	214	45	other	other	ADJ
fnp-3050	214	46	cells	cell	NOUN
fnp-3050	214	47	[	[	X
fnp-3050	214	48	129	129	NUM
fnp-3050	214	49	]	]	PUNCT
fnp-3050	214	50	.	.	PUNCT
fnp-3050	215	1	microglia	microglia	NOUN
fnp-3050	215	2	could	could	AUX
fnp-3050	215	3	potentially	potentially	ADV
fnp-3050	215	4	play	play	VERB
fnp-3050	215	5	a	a	DET
fnp-3050	215	6	role	role	NOUN
fnp-3050	215	7	in	in	ADP
fnp-3050	215	8	spreading	spread	VERB
fnp-3050	215	9	of	of	ADP
fnp-3050	215	10	tau	tau	PROPN
fnp-3050	215	11	pathology	pathology	NOUN
fnp-3050	215	12	[	[	X
fnp-3050	215	13	130	130	NUM
fnp-3050	215	14	]	]	PUNCT
fnp-3050	215	15	.	.	PUNCT
fnp-3050	216	1	transcellular	transcellular	ADJ
fnp-3050	216	2	progression	progression	NOUN
fnp-3050	216	3	of	of	ADP
fnp-3050	216	4	tau	tau	PROPN
fnp-3050	216	5	seeds	seed	NOUN
fnp-3050	216	6	has	have	AUX
fnp-3050	216	7	been	be	AUX
fnp-3050	216	8	observed	observe	VERB
fnp-3050	216	9	in	in	ADP
fnp-3050	216	10	early	early	ADJ
fnp-3050	216	11	braak	braak	NOUN
fnp-3050	216	12	stage	stage	NOUN
fnp-3050	216	13	in	in	ADP
fnp-3050	216	14	regions	region	NOUN
fnp-3050	216	15	predicted	predict	VERB
fnp-3050	216	16	to	to	PART
fnp-3050	216	17	be	be	AUX
fnp-3050	216	18	free	free	ADJ
fnp-3050	216	19	of	of	ADP
fnp-3050	216	20	hp	hp	NOUN
fnp-3050	216	21	-	-	NOUN
fnp-3050	216	22	tau	tau	NOUN
fnp-3050	217	1	[	[	X
fnp-3050	217	2	131	131	NUM
fnp-3050	217	3	]	]	PUNCT
fnp-3050	217	4	.	.	PUNCT
fnp-3050	218	1	according	accord	VERB
fnp-3050	218	2	to	to	ADP
fnp-3050	218	3	the	the	DET
fnp-3050	218	4	original	original	ADJ
fnp-3050	218	5	staging	staging	NOUN
fnp-3050	218	6	[	[	X
fnp-3050	218	7	18	18	NUM
fnp-3050	218	8	]	]	PUNCT
fnp-3050	218	9	,	,	PUNCT
fnp-3050	218	10	the	the	DET
fnp-3050	218	11	first	first	ADJ
fnp-3050	218	12	nfts	nft	NOUN
fnp-3050	218	13	consistently	consistently	ADV
fnp-3050	218	14	occur	occur	VERB
fnp-3050	218	15	in	in	ADP
fnp-3050	218	16	the	the	DET
fnp-3050	218	17	transentorhinal	transentorhinal	ADJ
fnp-3050	218	18	(	(	PUNCT
fnp-3050	218	19	perirhinal	perirhinal	ADJ
fnp-3050	218	20	)	)	PUNCT
fnp-3050	218	21	region	region	NOUN
fnp-3050	218	22	(	(	PUNCT
fnp-3050	218	23	stage	stage	NOUN
fnp-3050	218	24	i	i	PROPN
fnp-3050	218	25	)	)	PUNCT
fnp-3050	218	26	along	along	ADP
fnp-3050	218	27	with	with	ADP
fnp-3050	218	28	the	the	DET
fnp-3050	218	29	entorhinal	entorhinal	ADJ
fnp-3050	218	30	cortex	cortex	NOUN
fnp-3050	218	31	,	,	PUNCT
fnp-3050	218	32	followed	follow	VERB
fnp-3050	218	33	by	by	ADP
fnp-3050	218	34	the	the	DET
fnp-3050	218	35	ca1	ca1	PROPN
fnp-3050	218	36	region	region	NOUN
fnp-3050	218	37	of	of	ADP
fnp-3050	218	38	the	the	DET
fnp-3050	218	39	hippocampua	hippocampua	PROPN
fnp-3050	218	40	(	(	PUNCT
fnp-3050	218	41	stage	stage	PROPN
fnp-3050	218	42	ii	ii	PROPN
fnp-3050	218	43	)	)	PUNCT
fnp-3050	218	44	,	,	PUNCT
fnp-3050	218	45	indicating	indicate	VERB
fnp-3050	218	46	a	a	DET
fnp-3050	218	47	preclinical	preclinical	ADJ
fnp-3050	218	48	phase	phase	NOUN
fnp-3050	218	49	of	of	ADP
fnp-3050	218	50	ad	ad	NOUN
fnp-3050	218	51	which	which	PRON
fnp-3050	218	52	can	can	AUX
fnp-3050	218	53	last	last	VERB
fnp-3050	218	54	up	up	ADP
fnp-3050	218	55	to	to	PART
fnp-3050	218	56	20	20	NUM
fnp-3050	218	57	years	year	NOUN
fnp-3050	218	58	.	.	PUNCT
fnp-3050	219	1	limbic	limbic	ADJ
fnp-3050	219	2	structures	structure	NOUN
fnp-3050	219	3	,	,	PUNCT
fnp-3050	219	4	such	such	ADJ
fnp-3050	219	5	as	as	ADP
fnp-3050	219	6	the	the	DET
fnp-3050	219	7	subiculum	subiculum	NOUN
fnp-3050	219	8	of	of	ADP
fnp-3050	219	9	the	the	DET
fnp-3050	219	10	hippocampal	hippocampal	ADJ
fnp-3050	219	11	formation	formation	NOUN
fnp-3050	219	12	are	be	AUX
fnp-3050	219	13	affected	affect	VERB
fnp-3050	219	14	next	next	ADV
fnp-3050	219	15	(	(	PUNCT
fnp-3050	219	16	stage	stage	NOUN
fnp-3050	219	17	iii	iii	PROPN
fnp-3050	219	18	)	)	PUNCT
fnp-3050	219	19	,	,	PUNCT
fnp-3050	219	20	followed	follow	VERB
fnp-3050	219	21	by	by	ADP
fnp-3050	219	22	the	the	DET
fnp-3050	219	23	amygdala	amygdala	NOUN
fnp-3050	219	24	,	,	PUNCT
fnp-3050	219	25	thalamus	thalamus	NOUN
fnp-3050	219	26	,	,	PUNCT
fnp-3050	219	27	and	and	CCONJ
fnp-3050	219	28	claustrum	claustrum	NOUN
fnp-3050	219	29	(	(	PUNCT
fnp-3050	219	30	stage	stage	NOUN
fnp-3050	219	31	iv	iv	NUM
fnp-3050	219	32	)	)	PUNCT
fnp-3050	219	33	.	.	PUNCT
fnp-3050	220	1	stages	stage	NOUN
fnp-3050	220	2	iii	iii	NOUN
fnp-3050	220	3	and	and	CCONJ
fnp-3050	220	4	iv	iv	NOUN
fnp-3050	220	5	are	be	AUX
fnp-3050	220	6	often	often	ADV
fnp-3050	220	7	correlated	correlate	VERB
fnp-3050	220	8	clinically	clinically	ADV
fnp-3050	220	9	with	with	ADP
fnp-3050	220	10	mild	mild	ADJ
fnp-3050	220	11	cognitive	cognitive	ADJ
fnp-3050	220	12	impairment	impairment	NOUN
fnp-3050	220	13	(	(	PUNCT
fnp-3050	220	14	mci	mci	NOUN
fnp-3050	220	15	)	)	PUNCT
fnp-3050	220	16	.	.	PUNCT
fnp-3050	221	1	in	in	ADP
fnp-3050	221	2	stage	stage	NOUN
fnp-3050	221	3	v	v	NOUN
fnp-3050	221	4	,	,	PUNCT
fnp-3050	221	5	nfts	nft	NOUN
fnp-3050	221	6	spread	spread	VERB
fnp-3050	221	7	to	to	ADP
fnp-3050	221	8	isocortical	isocortical	ADJ
fnp-3050	221	9	areas	area	NOUN
fnp-3050	221	10	with	with	ADP
fnp-3050	221	11	the	the	DET
fnp-3050	221	12	association	association	NOUN
fnp-3050	221	13	areas	area	NOUN
fnp-3050	221	14	being	be	AUX
fnp-3050	221	15	affected	affect	VERB
fnp-3050	221	16	prior	prior	ADV
fnp-3050	221	17	and	and	CCONJ
fnp-3050	221	18	more	more	ADV
fnp-3050	221	19	severely	severely	ADV
fnp-3050	221	20	,	,	PUNCT
fnp-3050	221	21	followed	follow	VERB
fnp-3050	221	22	in	in	ADP
fnp-3050	221	23	stage	stage	NOUN
fnp-3050	221	24	vi	vi	NOUN
fnp-3050	221	25	by	by	ADP
fnp-3050	221	26	the	the	DET
fnp-3050	221	27	primary	primary	ADJ
fnp-3050	221	28	sensory	sensory	NOUN
fnp-3050	221	29	,	,	PUNCT
fnp-3050	221	30	motor	motor	NOUN
fnp-3050	221	31	and	and	CCONJ
fnp-3050	221	32	visual	visual	ADJ
fnp-3050	221	33	areas	area	NOUN
fnp-3050	221	34	,	,	PUNCT
fnp-3050	221	35	which	which	PRON
fnp-3050	221	36	is	be	AUX
fnp-3050	221	37	usually	usually	ADV
fnp-3050	221	38	associated	associate	VERB
fnp-3050	221	39	with	with	ADP
fnp-3050	221	40	overt	overt	ADJ
fnp-3050	221	41	dementia	dementia	NOUN
fnp-3050	221	42	(	(	PUNCT
fnp-3050	221	43	fig	fig	NOUN
fnp-3050	221	44	.	.	PUNCT
fnp-3050	222	1	6	6	NUM
fnp-3050	222	2	)	)	PUNCT
fnp-3050	222	3	.	.	PUNCT
fnp-3050	223	1	this	this	DET
fnp-3050	223	2	nft	nft	PROPN
fnp-3050	223	3	staging	staging	NOUN
fnp-3050	223	4	has	have	AUX
fnp-3050	223	5	been	be	AUX
fnp-3050	223	6	widely	widely	ADV
fnp-3050	223	7	accepted	accept	VERB
fnp-3050	223	8	in	in	ADP
fnp-3050	223	9	routine	routine	ADJ
fnp-3050	223	10	pathology	pathology	NOUN
fnp-3050	223	11	and	and	CCONJ
fnp-3050	223	12	appears	appear	VERB
fnp-3050	223	13	well	well	ADV
fnp-3050	223	14	correlated	correlate	VERB
fnp-3050	223	15	with	with	ADP
fnp-3050	223	16	the	the	DET
fnp-3050	223	17	clinical	clinical	ADJ
fnp-3050	223	18	status	status	NOUN
fnp-3050	223	19	,	,	PUNCT
fnp-3050	223	20	at	at	ADP
fnp-3050	223	21	least	least	ADJ
fnp-3050	223	22	in	in	ADP
fnp-3050	223	23	the	the	DET
fnp-3050	223	24	amnestic	amnestic	ADJ
fnp-3050	223	25	ad	ad	NOUN
fnp-3050	223	26	.	.	PUNCT
fnp-3050	224	1	imaging	imaging	NOUN
fnp-3050	224	2	in	in	ADP
fnp-3050	224	3	vivo	vivo	NOUN
fnp-3050	224	4	tau	tau	PROPN
fnp-3050	224	5	pathology	pathology	NOUN
fnp-3050	224	6	with	with	ADP
fnp-3050	224	7	tau	tau	NOUN
fnp-3050	224	8	-	-	PUNCT
fnp-3050	224	9	specific	specific	ADJ
fnp-3050	224	10	pet	pet	ADJ
fnp-3050	224	11	tracers	tracer	NOUN
fnp-3050	224	12	identified	identify	VERB
fnp-3050	224	13	nft	nft	PROPN
fnp-3050	224	14	pathology	pathology	PROPN
fnp-3050	224	15	reflecting	reflect	VERB
fnp-3050	224	16	braak	braak	NOUN
fnp-3050	224	17	stages	stage	NOUN
fnp-3050	224	18	iv	iv	ADP
fnp-3050	224	19	or	or	CCONJ
fnp-3050	224	20	higher	high	ADJ
fnp-3050	224	21	.	.	PUNCT
fnp-3050	225	1	it	it	PRON
fnp-3050	225	2	rendered	render	VERB
fnp-3050	225	3	it	it	PRON
fnp-3050	225	4	possible	possible	ADJ
fnp-3050	225	5	to	to	PART
fnp-3050	225	6	study	study	VERB
fnp-3050	225	7	the	the	DET
fnp-3050	225	8	temporal	temporal	ADJ
fnp-3050	225	9	progression	progression	NOUN
fnp-3050	225	10	of	of	ADP
fnp-3050	225	11	tau	tau	PROPN
fnp-3050	225	12	pathology	pathology	NOUN
fnp-3050	225	13	in	in	ADP
fnp-3050	225	14	vivo	vivo	NOUN
fnp-3050	225	15	,	,	PUNCT
fnp-3050	225	16	and	and	CCONJ
fnp-3050	225	17	,	,	PUNCT
fnp-3050	225	18	therefore	therefore	ADV
fnp-3050	225	19	,	,	PUNCT
fnp-3050	225	20	can	can	AUX
fnp-3050	225	21	be	be	AUX
fnp-3050	225	22	used	use	VERB
fnp-3050	225	23	as	as	ADP
fnp-3050	225	24	a	a	DET
fnp-3050	225	25	reliable	reliable	ADJ
fnp-3050	225	26	biomarker	biomarker	NOUN
fnp-3050	225	27	of	of	ADP
fnp-3050	225	28	tau	tau	PROPN
fnp-3050	225	29	pathology	pathology	NOUN
fnp-3050	226	1	[	[	X
fnp-3050	226	2	132	132	NUM
fnp-3050	226	3	-	-	SYM
fnp-3050	226	4	137	137	NUM
fnp-3050	226	5	]	]	PUNCT
fnp-3050	226	6	.	.	PUNCT
fnp-3050	227	1	there	there	PRON
fnp-3050	227	2	is	be	VERB
fnp-3050	227	3	an	an	DET
fnp-3050	227	4	inverse	inverse	ADJ
fnp-3050	227	5	correlation	correlation	NOUN
fnp-3050	227	6	between	between	ADP
fnp-3050	227	7	the	the	DET
fnp-3050	227	8	accumulation	accumulation	NOUN
fnp-3050	227	9	of	of	ADP
fnp-3050	227	10	nfts	nft	NOUN
fnp-3050	227	11	and	and	CCONJ
fnp-3050	227	12	cognitive	cognitive	ADJ
fnp-3050	227	13	status	status	NOUN
fnp-3050	227	14	;	;	PUNCT
fnp-3050	227	15	the	the	DET
fnp-3050	227	16	spread	spread	NOUN
fnp-3050	227	17	and	and	CCONJ
fnp-3050	227	18	level	level	NOUN
fnp-3050	227	19	of	of	ADP
fnp-3050	227	20	tau	tau	PROPN
fnp-3050	227	21	accumulation	accumulation	NOUN
fnp-3050	227	22	reflects	reflect	VERB
fnp-3050	227	23	the	the	DET
fnp-3050	227	24	severity	severity	NOUN
fnp-3050	227	25	of	of	ADP
fnp-3050	227	26	dementia	dementia	NOUN
fnp-3050	227	27	with	with	ADP
fnp-3050	227	28	time	time	NOUN
fnp-3050	227	29	[	[	X
fnp-3050	227	30	61	61	NUM
fnp-3050	227	31	,	,	PUNCT
fnp-3050	227	32	138	138	NUM
fnp-3050	227	33	-	-	SYM
fnp-3050	227	34	140	140	NUM
fnp-3050	227	35	]	]	PUNCT
fnp-3050	227	36	.	.	PUNCT
fnp-3050	228	1	the	the	DET
fnp-3050	228	2	seeding	seed	VERB
fnp-3050	228	3	activity	activity	NOUN
fnp-3050	228	4	is	be	AUX
fnp-3050	228	5	suggested	suggest	VERB
fnp-3050	228	6	to	to	PART
fnp-3050	228	7	begin	begin	VERB
fnp-3050	228	8	in	in	ADP
fnp-3050	228	9	the	the	DET
fnp-3050	228	10	transentorhinal	transentorhinal	ADJ
fnp-3050	228	11	/	/	SYM
fnp-3050	228	12	entorhinal	entorhinal	ADJ
fnp-3050	228	13	regions	region	NOUN
fnp-3050	228	14	and	and	CCONJ
fnp-3050	228	15	anticipates	anticipate	VERB
fnp-3050	228	16	hp	hp	PROPN
fnp-3050	228	17	-	-	PUNCT
fnp-3050	228	18	tau	tau	NOUN
fnp-3050	228	19	pathology	pathology	NOUN
fnp-3050	228	20	in	in	ADP
fnp-3050	228	21	ad	ad	NOUN
fnp-3050	228	22	,	,	PUNCT
fnp-3050	228	23	whereas	whereas	SCONJ
fnp-3050	228	24	the	the	DET
fnp-3050	228	25	locus	locus	NOUN
fnp-3050	228	26	ceruleus	ceruleus	NOUN
fnp-3050	228	27	(	(	PUNCT
fnp-3050	228	28	lc	lc	NOUN
fnp-3050	228	29	)	)	PUNCT
fnp-3050	228	30	showed	show	VERB
fnp-3050	228	31	seeding	seed	VERB
fnp-3050	228	32	only	only	ADV
fnp-3050	228	33	in	in	ADP
fnp-3050	228	34	later	later	ADV
fnp-3050	228	35	nft	nft	PROPN
fnp-3050	228	36	stages	stage	NOUN
fnp-3050	228	37	[	[	X
fnp-3050	228	38	141	141	NUM
fnp-3050	228	39	]	]	PUNCT
fnp-3050	228	40	.	.	PUNCT
fnp-3050	229	1	however	however	ADV
fnp-3050	229	2	,	,	PUNCT
fnp-3050	229	3	immunohistochemistry	immunohistochemistry	NOUN
fnp-3050	229	4	has	have	AUX
fnp-3050	229	5	detected	detect	VERB
fnp-3050	229	6	pre	pre	ADJ
fnp-3050	229	7	-	-	ADJ
fnp-3050	229	8	tangle	tangle	ADJ
fnp-3050	229	9	material	material	NOUN
fnp-3050	229	10	in	in	ADP
fnp-3050	229	11	multiple	multiple	ADJ
fnp-3050	229	12	subcortical	subcortical	ADJ
fnp-3050	229	13	regions	region	NOUN
fnp-3050	229	14	,	,	PUNCT
fnp-3050	229	15	especially	especially	ADV
fnp-3050	229	16	in	in	ADP
fnp-3050	229	17	locus	locus	ADJ
fnp-3050	229	18	ceruleus	ceruleus	NOUN
fnp-3050	229	19	(	(	PUNCT
fnp-3050	229	20	lc	lc	NOUN
fnp-3050	229	21	)	)	PUNCT
fnp-3050	229	22	neurons	neuron	NOUN
fnp-3050	229	23	[	[	X
fnp-3050	229	24	142	142	NUM
fnp-3050	229	25	-	-	SYM
fnp-3050	229	26	144	144	NUM
fnp-3050	229	27	]	]	PUNCT
fnp-3050	229	28	.	.	PUNCT
fnp-3050	230	1	involvement	involvement	NOUN
fnp-3050	230	2	of	of	ADP
fnp-3050	230	3	the	the	DET
fnp-3050	230	4	subcortical	subcortical	ADJ
fnp-3050	230	5	nuclei	nucleus	NOUN
fnp-3050	230	6	,	,	PUNCT
fnp-3050	230	7	not	not	PART
fnp-3050	230	8	considered	consider	VERB
fnp-3050	230	9	in	in	ADP
fnp-3050	230	10	the	the	DET
fnp-3050	230	11	original	original	ADJ
fnp-3050	230	12	braak	braak	NOUN
fnp-3050	230	13	scheme	scheme	NOUN
fnp-3050	230	14	,	,	PUNCT
fnp-3050	230	15	however	however	ADV
fnp-3050	230	16	,	,	PUNCT
fnp-3050	230	17	occurs	occur	VERB
fnp-3050	230	18	in	in	ADP
fnp-3050	230	19	early	early	ADJ
fnp-3050	230	20	stages	stage	NOUN
fnp-3050	230	21	of	of	ADP
fnp-3050	230	22	the	the	DET
fnp-3050	230	23	disease	disease	NOUN
fnp-3050	230	24	and	and	CCONJ
fnp-3050	230	25	has	have	VERB
fnp-3050	230	26	important	important	ADJ
fnp-3050	230	27	clinical	clinical	ADJ
fnp-3050	230	28	consequences	consequence	NOUN
fnp-3050	230	29	.	.	PUNCT
fnp-3050	231	1	the	the	DET
fnp-3050	231	2	cholinergic	cholinergic	ADJ
fnp-3050	231	3	nucleus	nucleus	ADJ
fnp-3050	231	4	basalis	basali	NOUN
fnp-3050	231	5	of	of	ADP
fnp-3050	231	6	meynert	meynert	NOUN
fnp-3050	231	7	and	and	CCONJ
fnp-3050	231	8	axons	axon	NOUN
fnp-3050	231	9	of	of	ADP
fnp-3050	231	10	the	the	DET
fnp-3050	231	11	adrenergic	adrenergic	ADJ
fnp-3050	231	12	lc	lc	NOUN
fnp-3050	231	13	projecting	project	VERB
fnp-3050	231	14	neurons	neuron	NOUN
fnp-3050	231	15	are	be	AUX
fnp-3050	231	16	affected	affect	VERB
fnp-3050	231	17	already	already	ADV
fnp-3050	231	18	in	in	ADP
fnp-3050	231	19	braak	braak	NOUN
fnp-3050	231	20	stages	stage	NOUN
fnp-3050	231	21	0	0	PUNCT
fnp-3050	231	22	/	/	SYM
fnp-3050	231	23	i	i	PROPN
fnp-3050	231	24	,	,	PUNCT
fnp-3050	231	25	associated	associate	VERB
fnp-3050	231	26	with	with	ADP
fnp-3050	231	27	severe	severe	ADJ
fnp-3050	231	28	neuronal	neuronal	ADJ
fnp-3050	231	29	loss	loss	NOUN
fnp-3050	231	30	,	,	PUNCT
fnp-3050	231	31	while	while	SCONJ
fnp-3050	231	32	moderate	moderate	ADJ
fnp-3050	231	33	to	to	ADP
fnp-3050	231	34	severe	severe	ADJ
fnp-3050	231	35	deposition	deposition	NOUN
fnp-3050	231	36	of	of	ADP
fnp-3050	231	37	tau	tau	PROPN
fnp-3050	231	38	in	in	ADP
fnp-3050	231	39	the	the	DET
fnp-3050	231	40	lc	lc	NOUN
fnp-3050	231	41	was	be	AUX
fnp-3050	231	42	only	only	ADV
fnp-3050	231	43	seen	see	VERB
fnp-3050	231	44	in	in	ADP
fnp-3050	231	45	braak	braak	NOUN
fnp-3050	231	46	stages	stage	NOUN
fnp-3050	231	47	above	above	ADP
fnp-3050	231	48	iv	iv	PRON
fnp-3050	232	1	[	[	X
fnp-3050	232	2	142	142	NUM
fnp-3050	232	3	]	]	PUNCT
fnp-3050	232	4	.	.	PUNCT
fnp-3050	233	1	the	the	DET
fnp-3050	233	2	intralaminar	intralaminar	NOUN
fnp-3050	233	3	nuclei	nucleus	NOUN
fnp-3050	233	4	of	of	ADP
fnp-3050	233	5	the	the	DET
fnp-3050	233	6	thalamus	thalamus	NOUN
fnp-3050	233	7	,	,	PUNCT
fnp-3050	233	8	the	the	DET
fnp-3050	233	9	pontine	pontine	ADJ
fnp-3050	233	10	parabrachial	parabrachial	ADJ
fnp-3050	233	11	region	region	NOUN
fnp-3050	233	12	,	,	PUNCT
fnp-3050	233	13	the	the	DET
fnp-3050	233	14	medullary	medullary	ADJ
fnp-3050	233	15	reticular	reticular	ADJ
fnp-3050	233	16	formation	formation	NOUN
fnp-3050	233	17	,	,	PUNCT
fnp-3050	233	18	the	the	DET
fnp-3050	233	19	dorsal	dorsal	NOUN
fnp-3050	233	20	raphe	raphe	NOUN
fnp-3050	233	21	nucleus	nucleus	NOUN
fnp-3050	233	22	,	,	PUNCT
fnp-3050	233	23	the	the	DET
fnp-3050	233	24	oculomotor	oculomotor	ADJ
fnp-3050	233	25	system	system	NOUN
fnp-3050	233	26	,	,	PUNCT
fnp-3050	233	27	and	and	CCONJ
fnp-3050	233	28	the	the	DET
fnp-3050	233	29	autonomous	autonomous	ADJ
fnp-3050	233	30	nuclei	nucleus	NOUN
fnp-3050	233	31	are	be	AUX
fnp-3050	233	32	also	also	ADV
fnp-3050	233	33	affected	affect	VERB
fnp-3050	233	34	early	early	ADV
fnp-3050	233	35	and	and	CCONJ
fnp-3050	233	36	increase	increase	VERB
fnp-3050	233	37	with	with	ADP
fnp-3050	233	38	disease	disease	NOUN
fnp-3050	233	39	progression	progression	NOUN
fnp-3050	233	40	[	[	X
fnp-3050	233	41	142	142	NUM
fnp-3050	233	42	,	,	PUNCT
fnp-3050	233	43	145	145	NUM
fnp-3050	233	44	-	-	SYM
fnp-3050	233	45	147	147	NUM
fnp-3050	233	46	]	]	PUNCT
fnp-3050	233	47	.	.	PUNCT
fnp-3050	234	1	nigral	nigral	ADJ
fnp-3050	234	2	pathology	pathology	NOUN
fnp-3050	234	3	including	include	VERB
fnp-3050	234	4	hp	hp	PROPN
fnp-3050	234	5	-	-	PROPN
fnp-3050	234	6	tau	tau	PROPN
fnp-3050	234	7	(	(	PUNCT
fnp-3050	234	8	nfts	nft	NOUN
fnp-3050	234	9	)	)	PUNCT
fnp-3050	234	10	accumulation	accumulation	NOUN
fnp-3050	234	11	and	and	CCONJ
fnp-3050	234	12	α	α	NOUN
fnp-3050	234	13	-	-	PUNCT
fnp-3050	234	14	synuclein	synuclein	NOUN
fnp-3050	234	15	aggregates	aggregate	NOUN
fnp-3050	234	16	is	be	AUX
fnp-3050	234	17	common	common	ADJ
fnp-3050	234	18	in	in	ADP
fnp-3050	234	19	elderly	elderly	ADJ
fnp-3050	234	20	patients	patient	NOUN
fnp-3050	234	21	with	with	ADP
fnp-3050	234	22	and	and	CCONJ
fnp-3050	234	23	without	without	ADP
fnp-3050	234	24	ad	ad	NOUN
fnp-3050	234	25	,	,	PUNCT
fnp-3050	234	26	and	and	CCONJ
fnp-3050	234	27	may	may	AUX
fnp-3050	234	28	be	be	AUX
fnp-3050	234	29	related	relate	VERB
fnp-3050	234	30	with	with	ADP
fnp-3050	234	31	extrapyramidal	extrapyramidal	ADJ
fnp-3050	234	32	symptoms	symptom	NOUN
fnp-3050	234	33	[	[	X
fnp-3050	234	34	148	148	NUM
fnp-3050	234	35	-	-	SYM
fnp-3050	234	36	150	150	NUM
fnp-3050	234	37	]	]	PUNCT
fnp-3050	234	38	.	.	PUNCT
fnp-3050	235	1	figure	figure	NOUN
fnp-3050	235	2	6	6	NUM
fnp-3050	235	3	.	.	PUNCT
fnp-3050	235	4	spreading	spread	VERB
fnp-3050	235	5	pattern	pattern	NOUN
fnp-3050	235	6	of	of	ADP
fnp-3050	235	7	neuritic	neuritic	ADJ
fnp-3050	235	8	ad	ad	NOUN
fnp-3050	235	9	pathology	pathology	NOUN
fnp-3050	235	10	.	.	PUNCT
fnp-3050	236	1	modified	modify	VERB
fnp-3050	236	2	from	from	ADP
fnp-3050	236	3	[	[	X
fnp-3050	236	4	18	18	NUM
fnp-3050	236	5	]	]	PUNCT
fnp-3050	236	6	.	.	PUNCT
fnp-3050	237	1	2.8	2.8	NUM
fnp-3050	237	2	.	.	PUNCT
fnp-3050	238	1	aβ	aβ	PRON
fnp-3050	238	2	and	and	CCONJ
fnp-3050	238	3	tau	tau	PROPN
fnp-3050	238	4	pathology	pathology	NOUN
fnp-3050	238	5	chicken	chicken	NOUN
fnp-3050	238	6	or	or	CCONJ
fnp-3050	238	7	egg	egg	NOUN
fnp-3050	238	8	?	?	PUNCT
fnp-3050	239	1	the	the	DET
fnp-3050	239	2	causes	cause	NOUN
fnp-3050	239	3	of	of	ADP
fnp-3050	239	4	sporadic	sporadic	ADJ
fnp-3050	239	5	ad	ad	NOUN
fnp-3050	239	6	are	be	AUX
fnp-3050	239	7	far	far	ADV
fnp-3050	239	8	from	from	ADP
fnp-3050	239	9	being	be	AUX
fnp-3050	239	10	understood	understand	VERB
fnp-3050	239	11	,	,	PUNCT
fnp-3050	239	12	while	while	SCONJ
fnp-3050	239	13	the	the	DET
fnp-3050	239	14	hallmarks	hallmark	NOUN
fnp-3050	239	15	that	that	PRON
fnp-3050	239	16	distinguish	distinguish	VERB
fnp-3050	239	17	ad	ad	NOUN
fnp-3050	239	18	from	from	ADP
fnp-3050	239	19	other	other	ADJ
fnp-3050	239	20	neurodegenerative	neurodegenerative	ADJ
fnp-3050	239	21	diseases	disease	NOUN
fnp-3050	239	22	–	–	PUNCT
fnp-3050	239	23	namely	namely	ADV
fnp-3050	239	24	aβ	aβ	ADP
fnp-3050	239	25	plaques	plaque	NOUN
fnp-3050	239	26	and	and	CCONJ
fnp-3050	239	27	nfts	nft	NOUN
fnp-3050	239	28	have	have	AUX
fnp-3050	239	29	been	be	AUX
fnp-3050	239	30	known	know	VERB
fnp-3050	239	31	for	for	ADP
fnp-3050	239	32	many	many	ADJ
fnp-3050	239	33	years	year	NOUN
fnp-3050	239	34	.	.	PUNCT
fnp-3050	240	1	the	the	DET
fnp-3050	240	2	physiological	physiological	ADJ
fnp-3050	240	3	and	and	CCONJ
fnp-3050	240	4	pathological	pathological	ADJ
fnp-3050	240	5	roles	role	NOUN
fnp-3050	240	6	of	of	ADP
fnp-3050	240	7	tau	tau	PROPN
fnp-3050	240	8	and	and	CCONJ
fnp-3050	240	9	aβ	aβ	NOUN
fnp-3050	240	10	,	,	PUNCT
fnp-3050	240	11	and	and	CCONJ
fnp-3050	240	12	their	their	PRON
fnp-3050	240	13	implications	implication	NOUN
fnp-3050	240	14	for	for	ADP
fnp-3050	240	15	ad	ad	NOUN
fnp-3050	240	16	pathology	pathology	NOUN
fnp-3050	240	17	and	and	CCONJ
fnp-3050	240	18	therapeutics	therapeutic	NOUN
fnp-3050	240	19	have	have	AUX
fnp-3050	240	20	been	be	AUX
fnp-3050	240	21	reviewed	review	VERB
fnp-3050	240	22	recently	recently	ADV
fnp-3050	240	23	[	[	X
fnp-3050	240	24	151	151	NUM
fnp-3050	240	25	]	]	PUNCT
fnp-3050	240	26	.	.	PUNCT
fnp-3050	241	1	many	many	ADJ
fnp-3050	241	2	studies	study	NOUN
fnp-3050	241	3	have	have	AUX
fnp-3050	241	4	linked	link	VERB
fnp-3050	241	5	aβ	aβ	NOUN
fnp-3050	241	6	and	and	CCONJ
fnp-3050	241	7	tau	tau	PROPN
fnp-3050	241	8	and	and	CCONJ
fnp-3050	241	9	raised	raise	VERB
fnp-3050	241	10	the	the	DET
fnp-3050	241	11	possibility	possibility	NOUN
fnp-3050	241	12	that	that	SCONJ
fnp-3050	241	13	protein	protein	NOUN
fnp-3050	241	14	-	-	PUNCT
fnp-3050	241	15	protein	protein	NOUN
fnp-3050	241	16	interactions	interaction	NOUN
fnp-3050	241	17	are	be	AUX
fnp-3050	241	18	the	the	DET
fnp-3050	241	19	key	key	NOUN
fnp-3050	241	20	for	for	ADP
fnp-3050	241	21	both	both	PRON
fnp-3050	241	22	spreading	spread	VERB
fnp-3050	241	23	and	and	CCONJ
fnp-3050	241	24	toxicity	toxicity	NOUN
fnp-3050	241	25	of	of	ADP
fnp-3050	241	26	these	these	DET
fnp-3050	241	27	two	two	NUM
fnp-3050	241	28	abnormal	abnormal	ADJ
fnp-3050	241	29	proteins	protein	NOUN
fnp-3050	241	30	[	[	X
fnp-3050	241	31	152	152	NUM
fnp-3050	241	32	]	]	PUNCT
fnp-3050	241	33	.	.	PUNCT
fnp-3050	242	1	several	several	ADJ
fnp-3050	242	2	models	model	NOUN
fnp-3050	242	3	of	of	ADP
fnp-3050	242	4	interaction	interaction	NOUN
fnp-3050	242	5	have	have	AUX
fnp-3050	242	6	been	be	AUX
fnp-3050	242	7	suggested	suggest	VERB
fnp-3050	242	8	:	:	PUNCT
fnp-3050	242	9	(	(	PUNCT
fnp-3050	242	10	1	1	X
fnp-3050	242	11	)	)	PUNCT
fnp-3050	242	12	the	the	DET
fnp-3050	242	13	seeding	seeding	NOUN
fnp-3050	242	14	of	of	ADP
fnp-3050	242	15	toxic	toxic	ADJ
fnp-3050	242	16	tau	tau	PROPN
fnp-3050	242	17	is	be	AUX
fnp-3050	242	18	enhanced	enhance	VERB
fnp-3050	242	19	by	by	ADP
fnp-3050	242	20	the	the	DET
fnp-3050	242	21	presence	presence	NOUN
fnp-3050	242	22	of	of	ADP
fnp-3050	242	23	aβ	aβ	NOUN
fnp-3050	242	24	;	;	PUNCT
fnp-3050	242	25	(	(	PUNCT
fnp-3050	242	26	2	2	X
fnp-3050	242	27	)	)	PUNCT
fnp-3050	242	28	the	the	DET
fnp-3050	242	29	toxicity	toxicity	NOUN
fnp-3050	242	30	of	of	ADP
fnp-3050	242	31	aβ	aβ	NOUN
fnp-3050	242	32	depends	depend	VERB
fnp-3050	242	33	of	of	ADP
fnp-3050	242	34	the	the	DET
fnp-3050	242	35	presence	presence	NOUN
fnp-3050	242	36	of	of	ADP
fnp-3050	242	37	tau	tau	PROPN
fnp-3050	242	38	;	;	PUNCT
fnp-3050	242	39	(	(	PUNCT
fnp-3050	242	40	3	3	X
fnp-3050	242	41	)	)	PUNCT
fnp-3050	242	42	aβ	aβ	NOUN
fnp-3050	242	43	and	and	CCONJ
fnp-3050	242	44	tau	tau	PROPN
fnp-3050	242	45	enhance	enhance	VERB
fnp-3050	242	46	each	each	DET
fnp-3050	242	47	other	other	ADJ
fnp-3050	242	48	's	's	PART
fnp-3050	242	49	toxicity	toxicity	NOUN
fnp-3050	242	50	.	.	PUNCT
fnp-3050	243	1	modern	modern	ADJ
fnp-3050	243	2	network	network	NOUN
fnp-3050	243	3	-	-	PUNCT
fnp-3050	243	4	based	base	VERB
fnp-3050	243	5	models	model	NOUN
fnp-3050	243	6	revealed	reveal	VERB
fnp-3050	243	7	ways	way	NOUN
fnp-3050	243	8	in	in	ADP
fnp-3050	243	9	which	which	PRON
fnp-3050	243	10	aβ	aβ	NOUN
fnp-3050	243	11	and	and	CCONJ
fnp-3050	243	12	tau	tau	PROPN
fnp-3050	243	13	protein	protein	NOUN
fnp-3050	243	14	might	might	AUX
fnp-3050	243	15	interact	interact	VERB
fnp-3050	243	16	with	with	ADP
fnp-3050	243	17	each	each	DET
fnp-3050	243	18	other	other	ADJ
fnp-3050	243	19	to	to	PART
fnp-3050	243	20	enhance	enhance	VERB
fnp-3050	243	21	the	the	DET
fnp-3050	243	22	propagation	propagation	NOUN
fnp-3050	243	23	of	of	ADP
fnp-3050	243	24	ad	ad	NOUN
fnp-3050	243	25	,	,	PUNCT
fnp-3050	243	26	thus	thus	ADV
fnp-3050	243	27	shedding	shed	VERB
fnp-3050	243	28	light	light	NOUN
fnp-3050	243	29	on	on	ADP
fnp-3050	243	30	the	the	DET
fnp-3050	243	31	importance	importance	NOUN
fnp-3050	243	32	of	of	ADP
fnp-3050	243	33	protein	protein	NOUN
fnp-3050	243	34	clearance	clearance	NOUN
fnp-3050	243	35	and	and	CCONJ
fnp-3050	243	36	protein	protein	NOUN
fnp-3050	243	37	interaction	interaction	NOUN
fnp-3050	243	38	mechanisms	mechanism	NOUN
fnp-3050	243	39	in	in	ADP
fnp-3050	243	40	the	the	DET
fnp-3050	243	41	development	development	NOUN
fnp-3050	243	42	of	of	ADP
fnp-3050	243	43	ad	ad	NOUN
fnp-3050	243	44	pathology	pathology	NOUN
fnp-3050	243	45	[	[	X
fnp-3050	243	46	153	153	NUM
fnp-3050	243	47	,	,	PUNCT
fnp-3050	243	48	154	154	NUM
fnp-3050	243	49	]	]	PUNCT
fnp-3050	244	1	[	[	X
fnp-3050	244	2	155	155	NUM
fnp-3050	244	3	]	]	PUNCT
fnp-3050	244	4	.	.	PUNCT
fnp-3050	245	1	soluble	soluble	ADJ
fnp-3050	245	2	oligomeric	oligomeric	ADJ
fnp-3050	245	3	aβ	aβ	VERB
fnp-3050	245	4	is	be	AUX
fnp-3050	245	5	hypothesized	hypothesize	VERB
fnp-3050	245	6	to	to	PART
fnp-3050	245	7	be	be	AUX
fnp-3050	245	8	a	a	DET
fnp-3050	245	9	possible	possible	ADJ
fnp-3050	245	10	cause	cause	NOUN
fnp-3050	245	11	of	of	ADP
fnp-3050	245	12	the	the	DET
fnp-3050	245	13	hyperphosphorylation	hyperphosphorylation	NOUN
fnp-3050	245	14	of	of	ADP
fnp-3050	245	15	tau	tau	PROPN
fnp-3050	245	16	and	and	CCONJ
fnp-3050	245	17	the	the	DET
fnp-3050	245	18	development	development	NOUN
fnp-3050	245	19	of	of	ADP
fnp-3050	245	20	nfts	nft	NOUN
fnp-3050	245	21	.	.	PUNCT
fnp-3050	246	1	the	the	DET
fnp-3050	246	2	presence	presence	NOUN
fnp-3050	246	3	of	of	ADP
fnp-3050	246	4	aps	aps	PROPN
fnp-3050	246	5	accelerates	accelerate	VERB
fnp-3050	246	6	both	both	CCONJ
fnp-3050	246	7	the	the	DET
fnp-3050	246	8	formation	formation	NOUN
fnp-3050	246	9	of	of	ADP
fnp-3050	246	10	hp	hp	ADJ
fnp-3050	246	11	-	-	PUNCT
fnp-3050	246	12	tau	tau	NOUN
fnp-3050	246	13	aggregates	aggregate	NOUN
fnp-3050	246	14	[	[	X
fnp-3050	246	15	156	156	NUM
fnp-3050	246	16	]	]	PUNCT
fnp-3050	246	17	and	and	CCONJ
fnp-3050	246	18	its	its	PRON
fnp-3050	246	19	interneuronal	interneuronal	ADJ
fnp-3050	246	20	transfer	transfer	NOUN
fnp-3050	246	21	[	[	X
fnp-3050	246	22	157	157	NUM
fnp-3050	246	23	]	]	PUNCT
fnp-3050	246	24	.	.	PUNCT
fnp-3050	247	1	the	the	DET
fnp-3050	247	2	aβo	aβo	PROPN
fnp-3050	247	3	hypothesis	hypothesis	NOUN
fnp-3050	247	4	was	be	AUX
fnp-3050	247	5	introduced	introduce	VERB
fnp-3050	247	6	in	in	ADP
fnp-3050	247	7	1998	1998	NUM
fnp-3050	247	8	,	,	PUNCT
fnp-3050	247	9	suggesting	suggest	VERB
fnp-3050	247	10	that	that	SCONJ
fnp-3050	247	11	the	the	DET
fnp-3050	247	12	brain	brain	NOUN
fnp-3050	247	13	damage	damage	NOUN
fnp-3050	247	14	leading	lead	VERB
fnp-3050	247	15	to	to	ADP
fnp-3050	247	16	ad	ad	NOUN
fnp-3050	247	17	was	be	AUX
fnp-3050	247	18	initiated	initiate	VERB
fnp-3050	247	19	by	by	ADP
fnp-3050	247	20	soluble	soluble	ADJ
fnp-3050	247	21	ligand	ligand	NOUN
fnp-3050	247	22	-	-	PUNCT
fnp-3050	247	23	like	like	ADJ
fnp-3050	247	24	aβos	aβos	NOUN
fnp-3050	248	1	[	[	X
fnp-3050	248	2	158	158	NUM
fnp-3050	248	3	]	]	PUNCT
fnp-3050	248	4	.	.	PUNCT
fnp-3050	249	1	the	the	DET
fnp-3050	249	2	extension	extension	NOUN
fnp-3050	249	3	of	of	ADP
fnp-3050	249	4	tau	tau	PROPN
fnp-3050	249	5	pathology	pathology	NOUN
fnp-3050	249	6	is	be	AUX
fnp-3050	249	7	different	different	ADJ
fnp-3050	249	8	from	from	ADP
fnp-3050	249	9	the	the	DET
fnp-3050	249	10	spread	spread	NOUN
fnp-3050	249	11	of	of	ADP
fnp-3050	249	12	aβ	aβ	NOUN
fnp-3050	249	13	deposition	deposition	NOUN
fnp-3050	249	14	that	that	PRON
fnp-3050	249	15	is	be	AUX
fnp-3050	249	16	related	relate	VERB
fnp-3050	249	17	to	to	ADP
fnp-3050	249	18	diffusion	diffusion	NOUN
fnp-3050	249	19	of	of	ADP
fnp-3050	249	20	soluble	soluble	ADJ
fnp-3050	249	21	aβ	aβ	NOUN
fnp-3050	249	22	in	in	ADP
fnp-3050	249	23	the	the	DET
fnp-3050	249	24	extracellular	extracellular	ADJ
fnp-3050	249	25	space	space	NOUN
fnp-3050	249	26	[	[	X
fnp-3050	249	27	159	159	NUM
fnp-3050	249	28	,	,	PUNCT
fnp-3050	249	29	160	160	NUM
fnp-3050	249	30	]	]	PUNCT
fnp-3050	249	31	.	.	PUNCT
fnp-3050	250	1	quantification	quantification	NOUN
fnp-3050	250	2	of	of	ADP
fnp-3050	250	3	adnc	adnc	NOUN
fnp-3050	250	4	in	in	ADP
fnp-3050	250	5	formalin	formalin	NOUN
fnp-3050	250	6	-	-	PUNCT
fnp-3050	250	7	fixed	fix	VERB
fnp-3050	250	8	post	post	ADJ
fnp-3050	250	9	-	-	ADJ
fnp-3050	250	10	mortem	mortem	ADJ
fnp-3050	250	11	human	human	ADJ
fnp-3050	250	12	brain	brain	NOUN
fnp-3050	250	13	tissue	tissue	NOUN
fnp-3050	250	14	detected	detect	VERB
fnp-3050	250	15	high	high	ADJ
fnp-3050	250	16	amounts	amount	NOUN
fnp-3050	250	17	of	of	ADP
fnp-3050	250	18	aβ	aβ	PRON
fnp-3050	250	19	in	in	ADP
fnp-3050	250	20	the	the	DET
fnp-3050	250	21	frontal	frontal	ADJ
fnp-3050	250	22	cortex	cortex	NOUN
fnp-3050	250	23	and	and	CCONJ
fnp-3050	250	24	striatum	striatum	NOUN
fnp-3050	250	25	,	,	PUNCT
fnp-3050	250	26	and	and	CCONJ
fnp-3050	250	27	of	of	ADP
fnp-3050	250	28	hp	hp	PROPN
fnp-3050	250	29	-	-	NOUN
fnp-3050	250	30	tau	tau	NOUN
fnp-3050	250	31	in	in	ADP
fnp-3050	250	32	the	the	DET
fnp-3050	250	33	frontal	frontal	ADJ
fnp-3050	250	34	cortex	cortex	NOUN
fnp-3050	250	35	and	and	CCONJ
fnp-3050	250	36	hippocampus	hippocampus	NOUN
fnp-3050	250	37	of	of	ADP
fnp-3050	250	38	cases	case	NOUN
fnp-3050	250	39	with	with	ADP
fnp-3050	250	40	high	high	ADJ
fnp-3050	250	41	adnc	adnc	ADJ
fnp-3050	250	42	pathology	pathology	NOUN
fnp-3050	250	43	load	load	NOUN
fnp-3050	250	44	[	[	X
fnp-3050	250	45	161	161	NUM
fnp-3050	250	46	]	]	PUNCT
fnp-3050	250	47	.	.	PUNCT
fnp-3050	251	1	the	the	DET
fnp-3050	251	2	most	most	ADV
fnp-3050	251	3	recent	recent	ADJ
fnp-3050	251	4	version	version	NOUN
fnp-3050	251	5	of	of	ADP
fnp-3050	251	6	the	the	DET
fnp-3050	251	7	amyloid	amyloid	NOUN
fnp-3050	251	8	cascade	cascade	NOUN
fnp-3050	251	9	hypothesis	hypothesis	NOUN
fnp-3050	251	10	assumes	assume	VERB
fnp-3050	251	11	ad	ad	NOUN
fnp-3050	251	12	arises	arise	VERB
fnp-3050	251	13	from	from	ADP
fnp-3050	251	14	synaptic	synaptic	ADJ
fnp-3050	251	15	toxicity	toxicity	NOUN
fnp-3050	251	16	mediated	mediate	VERB
fnp-3050	251	17	by	by	ADP
fnp-3050	251	18	soluble	soluble	ADJ
fnp-3050	251	19	aβos	aβos	NOUN
fnp-3050	251	20	,	,	PUNCT
fnp-3050	251	21	leading	lead	VERB
fnp-3050	251	22	to	to	ADP
fnp-3050	251	23	synaptic	synaptic	ADJ
fnp-3050	251	24	dysfunction	dysfunction	NOUN
fnp-3050	251	25	and	and	CCONJ
fnp-3050	251	26	loss	loss	NOUN
fnp-3050	251	27	.	.	PUNCT
fnp-3050	252	1	age	age	NOUN
fnp-3050	252	2	-	-	PUNCT
fnp-3050	252	3	related	relate	VERB
fnp-3050	252	4	aggregation	aggregation	NOUN
fnp-3050	252	5	of	of	ADP
fnp-3050	252	6	aβ	aβ	NOUN
fnp-3050	252	7	and	and	CCONJ
fnp-3050	252	8	its	its	PRON
fnp-3050	252	9	apparent	apparent	ADJ
fnp-3050	252	10	downstream	downstream	ADJ
fnp-3050	252	11	effects	effect	NOUN
fnp-3050	252	12	on	on	ADP
fnp-3050	252	13	microglia	microglia	ADJ
fnp-3050	252	14	,	,	PUNCT
fnp-3050	252	15	astrocytes	astrocyte	NOUN
fnp-3050	252	16	,	,	PUNCT
fnp-3050	252	17	and	and	CCONJ
fnp-3050	252	18	neurons	neuron	NOUN
fnp-3050	252	19	,	,	PUNCT
fnp-3050	252	20	including	include	VERB
fnp-3050	252	21	the	the	DET
fnp-3050	252	22	post	post	ADJ
fnp-3050	252	23	-	-	ADJ
fnp-3050	252	24	translational	translational	ADJ
fnp-3050	252	25	modification	modification	NOUN
fnp-3050	252	26	of	of	ADP
fnp-3050	252	27	the	the	DET
fnp-3050	252	28	tau	tau	PROPN
fnp-3050	252	29	protein	protein	NOUN
fnp-3050	252	30	,	,	PUNCT
fnp-3050	252	31	seems	seem	VERB
fnp-3050	252	32	necessary	necessary	ADJ
fnp-3050	252	33	for	for	ADP
fnp-3050	252	34	ad	ad	NOUN
fnp-3050	252	35	symptom	symptom	NOUN
fnp-3050	252	36	expression	expression	NOUN
fnp-3050	252	37	[	[	X
fnp-3050	252	38	162	162	NUM
fnp-3050	252	39	]	]	PUNCT
fnp-3050	252	40	.	.	PUNCT
fnp-3050	253	1	while	while	SCONJ
fnp-3050	253	2	an	an	DET
fnp-3050	253	3	optimal	optimal	ADJ
fnp-3050	253	4	concentration	concentration	NOUN
fnp-3050	253	5	of	of	ADP
fnp-3050	253	6	aβ	aβ	PRON
fnp-3050	253	7	is	be	AUX
fnp-3050	253	8	thought	think	VERB
fnp-3050	253	9	to	to	PART
fnp-3050	253	10	likely	likely	ADV
fnp-3050	253	11	maintain	maintain	VERB
fnp-3050	253	12	synapses	synapsis	NOUN
fnp-3050	253	13	,	,	PUNCT
fnp-3050	253	14	alterations	alteration	NOUN
fnp-3050	253	15	in	in	ADP
fnp-3050	253	16	the	the	DET
fnp-3050	253	17	proteolytic	proteolytic	ADJ
fnp-3050	253	18	processing	processing	NOUN
fnp-3050	253	19	of	of	ADP
fnp-3050	253	20	app	app	NOUN
fnp-3050	253	21	may	may	AUX
fnp-3050	253	22	cause	cause	VERB
fnp-3050	253	23	dyshomeostasis	dyshomeostasis	NOUN
fnp-3050	253	24	of	of	ADP
fnp-3050	253	25	aβ	aβ	NOUN
fnp-3050	253	26	,	,	PUNCT
fnp-3050	253	27	increasing	increase	VERB
fnp-3050	253	28	the	the	DET
fnp-3050	253	29	levels	level	NOUN
fnp-3050	253	30	of	of	ADP
fnp-3050	253	31	aβ-42	aβ-42	NOUN
fnp-3050	253	32	,	,	PUNCT
fnp-3050	253	33	and	and	CCONJ
fnp-3050	253	34	initiating	initiate	VERB
fnp-3050	253	35	ad	ad	NOUN
fnp-3050	253	36	by	by	ADP
fnp-3050	253	37	setting	set	VERB
fnp-3050	253	38	off	off	ADP
fnp-3050	253	39	a	a	DET
fnp-3050	253	40	chain	chain	NOUN
fnp-3050	253	41	of	of	ADP
fnp-3050	253	42	events	event	NOUN
fnp-3050	253	43	that	that	PRON
fnp-3050	253	44	leads	lead	VERB
fnp-3050	253	45	to	to	ADP
fnp-3050	253	46	the	the	DET
fnp-3050	253	47	accumulation	accumulation	NOUN
fnp-3050	253	48	of	of	ADP
fnp-3050	253	49	tau	tau	PROPN
fnp-3050	253	50	and	and	CCONJ
fnp-3050	253	51	downstream	downstream	ADJ
fnp-3050	253	52	neuronal	neuronal	ADJ
fnp-3050	253	53	cell	cell	NOUN
fnp-3050	253	54	death	death	NOUN
fnp-3050	254	1	[	[	X
fnp-3050	254	2	163	163	NUM
fnp-3050	254	3	]	]	PUNCT
fnp-3050	254	4	.	.	PUNCT
fnp-3050	254	5	soluble	soluble	ADJ
fnp-3050	254	6	aβos	aβos	PROPN
fnp-3050	254	7	are	be	AUX
fnp-3050	254	8	now	now	ADV
fnp-3050	254	9	suggested	suggest	VERB
fnp-3050	254	10	to	to	PART
fnp-3050	254	11	cause	cause	VERB
fnp-3050	254	12	neuronal	neuronal	ADJ
fnp-3050	254	13	damage	damage	NOUN
fnp-3050	254	14	[	[	X
fnp-3050	254	15	76	76	NUM
fnp-3050	254	16	]	]	PUNCT
fnp-3050	254	17	.	.	PUNCT
fnp-3050	255	1	they	they	PRON
fnp-3050	255	2	are	be	AUX
fnp-3050	255	3	believed	believe	VERB
fnp-3050	255	4	to	to	PART
fnp-3050	255	5	insert	insert	VERB
fnp-3050	255	6	into	into	ADP
fnp-3050	255	7	membranes	membrane	NOUN
fnp-3050	255	8	,	,	PUNCT
fnp-3050	255	9	while	while	SCONJ
fnp-3050	255	10	others	other	NOUN
fnp-3050	255	11	support	support	VERB
fnp-3050	255	12	ligand	ligand	NOUN
fnp-3050	255	13	-	-	PUNCT
fnp-3050	255	14	like	like	ADJ
fnp-3050	255	15	accumulation	accumulation	NOUN
fnp-3050	255	16	at	at	ADP
fnp-3050	255	17	particular	particular	ADJ
fnp-3050	255	18	synapses	synapsis	NOUN
fnp-3050	255	19	,	,	PUNCT
fnp-3050	255	20	providing	provide	VERB
fnp-3050	255	21	a	a	DET
fnp-3050	255	22	substantial	substantial	ADJ
fnp-3050	255	23	molecular	molecular	ADJ
fnp-3050	255	24	basis	basis	NOUN
fnp-3050	255	25	for	for	ADP
fnp-3050	255	26	the	the	DET
fnp-3050	255	27	cause	cause	NOUN
fnp-3050	255	28	of	of	ADP
fnp-3050	255	29	ad	ad	NOUN
fnp-3050	255	30	[	[	X
fnp-3050	255	31	164	164	NUM
fnp-3050	255	32	]	]	PUNCT
fnp-3050	255	33	.	.	PUNCT
fnp-3050	256	1	recent	recent	ADJ
fnp-3050	256	2	data	datum	NOUN
fnp-3050	256	3	support	support	VERB
fnp-3050	256	4	the	the	DET
fnp-3050	256	5	hypothesis	hypothesis	NOUN
fnp-3050	256	6	that	that	PRON
fnp-3050	256	7	aβ	aβ	NOUN
fnp-3050	256	8	enhances	enhance	VERB
fnp-3050	256	9	tau	tau	PROPN
fnp-3050	256	10	pathology	pathology	NOUN
fnp-3050	256	11	through	through	ADP
fnp-3050	256	12	increased	increase	VERB
fnp-3050	256	13	spreading	spread	VERB
fnp-3050	256	14	of	of	ADP
fnp-3050	256	15	tau	tau	PROPN
fnp-3050	256	16	induced	induce	VERB
fnp-3050	256	17	by	by	ADP
fnp-3050	256	18	phf	phf	NOUN
fnp-3050	256	19	in	in	ADP
fnp-3050	256	20	vivo	vivo	NOUN
fnp-3050	256	21	[	[	X
fnp-3050	256	22	165	165	NUM
fnp-3050	256	23	-	-	SYM
fnp-3050	256	24	168	168	NUM
fnp-3050	256	25	]	]	PUNCT
fnp-3050	256	26	,	,	PUNCT
fnp-3050	256	27	and	and	CCONJ
fnp-3050	256	28	that	that	SCONJ
fnp-3050	256	29	aβos	aβos	PROPN
fnp-3050	256	30	promote	promote	VERB
fnp-3050	256	31	tau	tau	NOUN
fnp-3050	256	32	seeding	seed	VERB
fnp-3050	256	33	potentiating	potentiate	VERB
fnp-3050	256	34	intracellular	intracellular	ADJ
fnp-3050	256	35	tau	tau	NOUN
fnp-3050	256	36	aggregation	aggregation	NOUN
fnp-3050	257	1	[	[	X
fnp-3050	257	2	169	169	NUM
fnp-3050	257	3	,	,	PUNCT
fnp-3050	257	4	170	170	NUM
fnp-3050	257	5	]	]	PUNCT
fnp-3050	257	6	.	.	PUNCT
fnp-3050	258	1	intraneuronal	intraneuronal	ADJ
fnp-3050	258	2	aβ	aβ	NOUN
fnp-3050	258	3	accumulation	accumulation	NOUN
fnp-3050	258	4	is	be	AUX
fnp-3050	258	5	suggested	suggest	VERB
fnp-3050	258	6	to	to	PART
fnp-3050	258	7	precede	precede	VERB
fnp-3050	258	8	tau	tau	PROPN
fnp-3050	258	9	pathology	pathology	NOUN
fnp-3050	258	10	in	in	ADP
fnp-3050	258	11	the	the	DET
fnp-3050	258	12	entorhinal	entorhinal	ADJ
fnp-3050	258	13	cortex	cortex	NOUN
fnp-3050	258	14	[	[	X
fnp-3050	258	15	171	171	NUM
fnp-3050	258	16	]	]	PUNCT
fnp-3050	258	17	and	and	CCONJ
fnp-3050	258	18	to	to	PART
fnp-3050	258	19	interact	interact	VERB
fnp-3050	258	20	with	with	ADP
fnp-3050	258	21	hippocampal	hippocampal	ADJ
fnp-3050	258	22	and	and	CCONJ
fnp-3050	258	23	cortical	cortical	ADJ
fnp-3050	258	24	tau	tau	PROPN
fnp-3050	258	25	pathology	pathology	NOUN
fnp-3050	258	26	,	,	PUNCT
fnp-3050	258	27	while	while	SCONJ
fnp-3050	258	28	in	in	ADP
fnp-3050	258	29	the	the	DET
fnp-3050	258	30	absence	absence	NOUN
fnp-3050	258	31	of	of	ADP
fnp-3050	258	32	aβ	aβ	DET
fnp-3050	258	33	tau	tau	PROPN
fnp-3050	258	34	deposition	deposition	NOUN
fnp-3050	258	35	may	may	AUX
fnp-3050	258	36	be	be	AUX
fnp-3050	258	37	insufficient	insufficient	ADJ
fnp-3050	258	38	for	for	ADP
fnp-3050	258	39	the	the	DET
fnp-3050	258	40	neurodegeneration	neurodegeneration	NOUN
fnp-3050	258	41	process	process	NOUN
fnp-3050	258	42	that	that	PRON
fnp-3050	258	43	leads	lead	VERB
fnp-3050	258	44	to	to	ADP
fnp-3050	258	45	ad	ad	NOUN
fnp-3050	258	46	[	[	X
fnp-3050	258	47	172	172	NUM
fnp-3050	258	48	]	]	PUNCT
fnp-3050	258	49	.	.	PUNCT
fnp-3050	259	1	many	many	ADJ
fnp-3050	259	2	data	datum	NOUN
fnp-3050	259	3	supporting	support	VERB
fnp-3050	259	4	a	a	DET
fnp-3050	259	5	toxic	toxic	ADJ
fnp-3050	259	6	role	role	NOUN
fnp-3050	259	7	for	for	ADP
fnp-3050	259	8	aβos	aβos	PROPN
fnp-3050	259	9	have	have	AUX
fnp-3050	259	10	backed	back	VERB
fnp-3050	259	11	the	the	DET
fnp-3050	259	12	aβo	aβo	NOUN
fnp-3050	259	13	hypothesis	hypothesis	NOUN
fnp-3050	259	14	for	for	ADP
fnp-3050	259	15	ad	ad	NOUN
fnp-3050	259	16	pathogenesis	pathogenesis	NOUN
fnp-3050	259	17	,	,	PUNCT
fnp-3050	259	18	but	but	CCONJ
fnp-3050	259	19	further	further	ADJ
fnp-3050	259	20	advances	advance	NOUN
fnp-3050	259	21	in	in	ADP
fnp-3050	259	22	aβo	aβo	NOUN
fnp-3050	259	23	structure	structure	NOUN
fnp-3050	259	24	-	-	PUNCT
fnp-3050	259	25	function	function	NOUN
fnp-3050	259	26	studies	study	NOUN
fnp-3050	259	27	are	be	AUX
fnp-3050	259	28	needed	need	VERB
fnp-3050	260	1	[	[	PUNCT
fnp-3050	260	2	158	158	NUM
fnp-3050	260	3	]	]	PUNCT
fnp-3050	260	4	.	.	PUNCT
fnp-3050	261	1	recent	recent	ADJ
fnp-3050	261	2	studies	study	NOUN
fnp-3050	261	3	point	point	VERB
fnp-3050	261	4	to	to	ADP
fnp-3050	261	5	a	a	DET
fnp-3050	261	6	role	role	NOUN
fnp-3050	261	7	for	for	ADP
fnp-3050	261	8	exosomes	exosome	NOUN
fnp-3050	261	9	in	in	ADP
fnp-3050	261	10	the	the	DET
fnp-3050	261	11	spreading	spreading	NOUN
fnp-3050	261	12	of	of	ADP
fnp-3050	261	13	toxic	toxic	ADJ
fnp-3050	261	14	aβos	aβos	NOUN
fnp-3050	261	15	and	and	CCONJ
fnp-3050	261	16	the	the	DET
fnp-3050	261	17	associated	associated	ADJ
fnp-3050	261	18	disease	disease	NOUN
fnp-3050	261	19	progression	progression	NOUN
fnp-3050	261	20	in	in	ADP
fnp-3050	261	21	the	the	DET
fnp-3050	261	22	ad	ad	NOUN
fnp-3050	261	23	brain	brain	NOUN
fnp-3050	261	24	[	[	X
fnp-3050	261	25	173	173	NUM
fnp-3050	261	26	]	]	PUNCT
fnp-3050	261	27	.	.	PUNCT
fnp-3050	262	1	however	however	ADV
fnp-3050	262	2	,	,	PUNCT
fnp-3050	262	3	the	the	DET
fnp-3050	262	4	traditional	traditional	ADJ
fnp-3050	262	5	consensus	consensus	NOUN
fnp-3050	262	6	of	of	ADP
fnp-3050	262	7	the	the	DET
fnp-3050	262	8	amyloid	amyloid	NOUN
fnp-3050	262	9	paradigm	paradigm	NOUN
fnp-3050	262	10	as	as	ADP
fnp-3050	262	11	a	a	DET
fnp-3050	262	12	singular	singular	ADJ
fnp-3050	262	13	cause	cause	NOUN
fnp-3050	262	14	of	of	ADP
fnp-3050	262	15	ad	ad	NOUN
fnp-3050	262	16	has	have	AUX
fnp-3050	262	17	been	be	AUX
fnp-3050	262	18	under	under	ADP
fnp-3050	262	19	revision	revision	NOUN
fnp-3050	262	20	,	,	PUNCT
fnp-3050	262	21	with	with	ADP
fnp-3050	262	22	the	the	DET
fnp-3050	262	23	accumulation	accumulation	NOUN
fnp-3050	262	24	of	of	ADP
fnp-3050	262	25	new	new	ADJ
fnp-3050	262	26	pathobiological	pathobiological	ADJ
fnp-3050	262	27	evidence	evidence	NOUN
fnp-3050	262	28	[	[	X
fnp-3050	262	29	174	174	NUM
fnp-3050	262	30	]	]	PUNCT
fnp-3050	262	31	.	.	PUNCT
fnp-3050	263	1	new	new	ADJ
fnp-3050	263	2	theories	theory	NOUN
fnp-3050	263	3	suggest	suggest	VERB
fnp-3050	263	4	that	that	SCONJ
fnp-3050	263	5	various	various	ADJ
fnp-3050	263	6	mechanisms	mechanism	NOUN
fnp-3050	263	7	,	,	PUNCT
fnp-3050	263	8	including	include	VERB
fnp-3050	263	9	prion	prion	NOUN
fnp-3050	263	10	-	-	PUNCT
fnp-3050	263	11	like	like	ADJ
fnp-3050	263	12	spread	spread	NOUN
fnp-3050	263	13	of	of	ADP
fnp-3050	263	14	aβ	aβ	NOUN
fnp-3050	263	15	and	and	CCONJ
fnp-3050	263	16	tau	tau	PROPN
fnp-3050	263	17	,	,	PUNCT
fnp-3050	263	18	vasoconstrictions	vasoconstriction	NOUN
fnp-3050	263	19	,	,	PUNCT
fnp-3050	263	20	growth	growth	NOUN
fnp-3050	263	21	hormone	hormone	NOUN
fnp-3050	263	22	secretagogue	secretagogue	NOUN
fnp-3050	263	23	receptor	receptor	NOUN
fnp-3050	263	24	1α	1α	NUM
fnp-3050	263	25	(	(	PUNCT
fnp-3050	263	26	ghsr1α	ghsr1α	ADJ
fnp-3050	263	27	)	)	PUNCT
fnp-3050	263	28	,	,	PUNCT
fnp-3050	263	29	and	and	CCONJ
fnp-3050	263	30	neuroinflammation	neuroinflammation	NOUN
fnp-3050	263	31	,	,	PUNCT
fnp-3050	263	32	come	come	VERB
fnp-3050	263	33	together	together	ADV
fnp-3050	263	34	at	at	ADP
fnp-3050	263	35	a	a	DET
fnp-3050	263	36	crossroad	crossroad	NOUN
fnp-3050	263	37	that	that	PRON
fnp-3050	263	38	ultimately	ultimately	ADV
fnp-3050	263	39	leads	lead	VERB
fnp-3050	263	40	to	to	ADP
fnp-3050	263	41	ad	ad	NOUN
fnp-3050	263	42	[	[	X
fnp-3050	263	43	11	11	NUM
fnp-3050	263	44	]	]	PUNCT
fnp-3050	263	45	,	,	PUNCT
fnp-3050	263	46	while	while	SCONJ
fnp-3050	263	47	others	other	NOUN
fnp-3050	263	48	suggested	suggest	VERB
fnp-3050	263	49	that	that	SCONJ
fnp-3050	263	50	extracellular	extracellular	ADJ
fnp-3050	263	51	aβ	aβ	NOUN
fnp-3050	263	52	and	and	CCONJ
fnp-3050	263	53	tau	tau	PROPN
fnp-3050	263	54	act	act	VERB
fnp-3050	263	55	in	in	ADP
fnp-3050	263	56	parallel	parallel	NOUN
fnp-3050	263	57	and	and	CCONJ
fnp-3050	263	58	upstream	upstream	NOUN
fnp-3050	263	59	of	of	ADP
fnp-3050	263	60	app	app	NOUN
fnp-3050	263	61	[	[	X
fnp-3050	263	62	175	175	NUM
fnp-3050	263	63	,	,	PUNCT
fnp-3050	263	64	176	176	NUM
fnp-3050	263	65	]	]	PUNCT
fnp-3050	263	66	.	.	PUNCT
fnp-3050	264	1	however	however	ADV
fnp-3050	264	2	,	,	PUNCT
fnp-3050	264	3	recent	recent	ADJ
fnp-3050	264	4	findings	finding	NOUN
fnp-3050	264	5	have	have	AUX
fnp-3050	264	6	shown	show	VERB
fnp-3050	264	7	that	that	SCONJ
fnp-3050	264	8	the	the	DET
fnp-3050	264	9	soluble	soluble	ADJ
fnp-3050	264	10	form	form	NOUN
fnp-3050	264	11	of	of	ADP
fnp-3050	264	12	app	app	NOUN
fnp-3050	264	13	binds	bind	VERB
fnp-3050	264	14	directly	directly	ADV
fnp-3050	264	15	to	to	PART
fnp-3050	264	16	gababr1a	gababr1a	VERB
fnp-3050	264	17	and	and	CCONJ
fnp-3050	264	18	modulates	modulate	VERB
fnp-3050	264	19	synaptic	synaptic	ADJ
fnp-3050	264	20	transmission	transmission	NOUN
fnp-3050	265	1	[	[	X
fnp-3050	265	2	177	177	NUM
fnp-3050	265	3	]	]	PUNCT
fnp-3050	265	4	,	,	PUNCT
fnp-3050	265	5	while	while	SCONJ
fnp-3050	265	6	that	that	PRON
fnp-3050	265	7	of	of	ADP
fnp-3050	265	8	aβ	aβ	PRON
fnp-3050	265	9	aggregates	aggregate	NOUN
fnp-3050	265	10	do	do	AUX
fnp-3050	265	11	not	not	PART
fnp-3050	265	12	need	need	VERB
fnp-3050	265	13	app	app	NOUN
fnp-3050	265	14	overexpression	overexpression	NOUN
fnp-3050	266	1	[	[	X
fnp-3050	266	2	178	178	NUM
fnp-3050	266	3	]	]	PUNCT
fnp-3050	267	1	but	but	CCONJ
fnp-3050	267	2	are	be	AUX
fnp-3050	267	3	performed	perform	VERB
fnp-3050	267	4	by	by	ADP
fnp-3050	267	5	extracellular	extracellular	ADJ
fnp-3050	267	6	exosomes	exosome	NOUN
fnp-3050	267	7	[	[	X
fnp-3050	267	8	173	173	NUM
fnp-3050	267	9	]	]	PUNCT
fnp-3050	267	10	.	.	PUNCT
fnp-3050	268	1	aβos	aβos	PROPN
fnp-3050	268	2	are	be	AUX
fnp-3050	268	3	deposited	deposit	VERB
fnp-3050	268	4	inside	inside	ADP
fnp-3050	268	5	synaptic	synaptic	ADJ
fnp-3050	268	6	terminals	terminal	NOUN
fnp-3050	268	7	[	[	X
fnp-3050	268	8	179	179	NUM
fnp-3050	268	9	]	]	PUNCT
fnp-3050	268	10	,	,	PUNCT
fnp-3050	268	11	enriched	enrich	VERB
fnp-3050	268	12	in	in	ADP
fnp-3050	268	13	small	small	ADJ
fnp-3050	268	14	vesicles	vesicle	NOUN
fnp-3050	268	15	at	at	ADP
fnp-3050	268	16	the	the	DET
fnp-3050	268	17	presynaptic	presynaptic	ADJ
fnp-3050	268	18	side	side	NOUN
fnp-3050	269	1	[	[	X
fnp-3050	269	2	47	47	NUM
fnp-3050	269	3	]	]	PUNCT
fnp-3050	269	4	,	,	PUNCT
fnp-3050	269	5	and	and	CCONJ
fnp-3050	269	6	enhance	enhance	VERB
fnp-3050	269	7	synaptic	synaptic	ADJ
fnp-3050	269	8	dysfunction	dysfunction	NOUN
fnp-3050	269	9	in	in	ADP
fnp-3050	269	10	ad	ad	NOUN
fnp-3050	270	1	[	[	X
fnp-3050	270	2	180	180	NUM
fnp-3050	270	3	]	]	PUNCT
fnp-3050	270	4	.	.	PUNCT
fnp-3050	271	1	according	accord	VERB
fnp-3050	271	2	to	to	ADP
fnp-3050	271	3	others	other	NOUN
fnp-3050	271	4	,	,	PUNCT
fnp-3050	271	5	aβ	aβ	NOUN
fnp-3050	271	6	and	and	CCONJ
fnp-3050	271	7	hp	hp	PROPN
fnp-3050	271	8	-	-	PROPN
fnp-3050	271	9	tau	tau	PROPN
fnp-3050	271	10	may	may	AUX
fnp-3050	271	11	develop	develop	VERB
fnp-3050	271	12	concomitantly	concomitantly	ADV
fnp-3050	271	13	within	within	ADP
fnp-3050	271	14	synaptic	synaptic	ADJ
fnp-3050	271	15	terminals	terminal	NOUN
fnp-3050	271	16	[	[	X
fnp-3050	271	17	181	181	NUM
fnp-3050	271	18	,	,	PUNCT
fnp-3050	271	19	182	182	NUM
fnp-3050	271	20	]	]	PUNCT
fnp-3050	271	21	and	and	CCONJ
fnp-3050	271	22	cause	cause	VERB
fnp-3050	271	23	abnormalities	abnormality	NOUN
fnp-3050	271	24	at	at	ADP
fnp-3050	271	25	synapses	synapsis	NOUN
fnp-3050	271	26	[	[	X
fnp-3050	271	27	183	183	NUM
fnp-3050	271	28	]	]	PUNCT
fnp-3050	271	29	.	.	PUNCT
fnp-3050	272	1	on	on	ADP
fnp-3050	272	2	the	the	DET
fnp-3050	272	3	other	other	ADJ
fnp-3050	272	4	hand	hand	NOUN
fnp-3050	272	5	,	,	PUNCT
fnp-3050	272	6	preclinical	preclinical	ADJ
fnp-3050	272	7	evidence	evidence	NOUN
fnp-3050	272	8	indicates	indicate	VERB
fnp-3050	272	9	that	that	SCONJ
fnp-3050	272	10	tau	tau	PROPN
fnp-3050	272	11	pathology	pathology	NOUN
fnp-3050	272	12	can	can	AUX
fnp-3050	272	13	progress	progress	VERB
fnp-3050	272	14	independently	independently	ADV
fnp-3050	272	15	of	of	ADP
fnp-3050	272	16	aβ	aβ	PRON
fnp-3050	272	17	accumulation	accumulation	NOUN
fnp-3050	272	18	and	and	CCONJ
fnp-3050	272	19	arises	arise	VERB
fnp-3050	272	20	downstream	downstream	ADV
fnp-3050	272	21	of	of	ADP
fnp-3050	272	22	genetic	genetic	ADJ
fnp-3050	272	23	risk	risk	NOUN
fnp-3050	272	24	factors	factor	NOUN
fnp-3050	272	25	for	for	ADP
fnp-3050	272	26	ad	ad	NOUN
fnp-3050	272	27	by	by	ADP
fnp-3050	272	28	an	an	DET
fnp-3050	272	29	aberrant	aberrant	ADJ
fnp-3050	272	30	metabolic	metabolic	NOUN
fnp-3050	272	31	pathway	pathway	NOUN
fnp-3050	273	1	[	[	X
fnp-3050	273	2	184	184	NUM
fnp-3050	273	3	]	]	PUNCT
fnp-3050	273	4	.	.	PUNCT
fnp-3050	274	1	the	the	DET
fnp-3050	274	2	argument	argument	NOUN
fnp-3050	274	3	that	that	PRON
fnp-3050	274	4	insoluble	insoluble	ADJ
fnp-3050	274	5	aβ	aβ	NOUN
fnp-3050	274	6	and	and	CCONJ
fnp-3050	274	7	tau	tau	PROPN
fnp-3050	274	8	deposits	deposit	NOUN
fnp-3050	274	9	begin	begin	VERB
fnp-3050	274	10	forming	form	VERB
fnp-3050	274	11	concomitantly	concomitantly	ADV
fnp-3050	274	12	in	in	ADP
fnp-3050	274	13	the	the	DET
fnp-3050	274	14	cerebral	cerebral	ADJ
fnp-3050	274	15	cortex	cortex	NOUN
fnp-3050	274	16	of	of	ADP
fnp-3050	274	17	ad	ad	NOUN
fnp-3050	274	18	brains	brain	NOUN
fnp-3050	274	19	would	would	AUX
fnp-3050	274	20	be	be	AUX
fnp-3050	274	21	consistent	consistent	ADJ
fnp-3050	274	22	with	with	ADP
fnp-3050	274	23	the	the	DET
fnp-3050	274	24	argument	argument	NOUN
fnp-3050	274	25	in	in	ADP
fnp-3050	274	26	favor	favor	NOUN
fnp-3050	274	27	of	of	ADP
fnp-3050	274	28	the	the	DET
fnp-3050	274	29	pathogenic	pathogenic	ADJ
fnp-3050	274	30	importance	importance	NOUN
fnp-3050	274	31	of	of	ADP
fnp-3050	274	32	tau	tau	PROPN
fnp-3050	274	33	deposition	deposition	NOUN
fnp-3050	274	34	.	.	PUNCT
fnp-3050	275	1	recent	recent	ADJ
fnp-3050	275	2	quantitative	quantitative	ADJ
fnp-3050	275	3	studies	study	NOUN
fnp-3050	275	4	did	do	AUX
fnp-3050	275	5	not	not	PART
fnp-3050	275	6	find	find	VERB
fnp-3050	275	7	regional	regional	ADJ
fnp-3050	275	8	association	association	NOUN
fnp-3050	275	9	between	between	ADP
fnp-3050	275	10	aβ-42	aβ-42	ADJ
fnp-3050	275	11	and	and	CCONJ
fnp-3050	275	12	insoluble	insoluble	ADJ
fnp-3050	275	13	tau	tau	PROPN
fnp-3050	275	14	,	,	PUNCT
fnp-3050	275	15	but	but	CCONJ
fnp-3050	275	16	a	a	DET
fnp-3050	275	17	higher	high	ADJ
fnp-3050	275	18	regional	regional	ADJ
fnp-3050	275	19	association	association	NOUN
fnp-3050	275	20	between	between	ADP
fnp-3050	275	21	total	total	NOUN
fnp-3050	275	22	aβ-42	aβ-42	ADV
fnp-3050	275	23	and	and	CCONJ
fnp-3050	275	24	soluble	soluble	ADJ
fnp-3050	275	25	tau	tau	PROPN
fnp-3050	275	26	phosphorylation	phosphorylation	NOUN
fnp-3050	275	27	.	.	PUNCT
fnp-3050	276	1	this	this	PRON
fnp-3050	276	2	provides	provide	VERB
fnp-3050	276	3	evidence	evidence	NOUN
fnp-3050	276	4	supporting	support	VERB
fnp-3050	276	5	the	the	DET
fnp-3050	276	6	local	local	ADJ
fnp-3050	276	7	interplay	interplay	NOUN
fnp-3050	276	8	between	between	ADP
fnp-3050	276	9	aβ	aβ	NOUN
fnp-3050	276	10	and	and	CCONJ
fnp-3050	276	11	soluble	soluble	ADJ
fnp-3050	276	12	hp	hp	NOUN
fnp-3050	276	13	-	-	NOUN
fnp-3050	276	14	tau	tau	NOUN
fnp-3050	276	15	in	in	ADP
fnp-3050	276	16	ad	ad	NOUN
fnp-3050	276	17	brains	brain	NOUN
fnp-3050	276	18	[	[	X
fnp-3050	276	19	185	185	NUM
fnp-3050	276	20	]	]	PUNCT
fnp-3050	276	21	,	,	PUNCT
fnp-3050	276	22	and	and	CCONJ
fnp-3050	276	23	accumulating	accumulate	VERB
fnp-3050	276	24	evidence	evidence	NOUN
fnp-3050	276	25	suggests	suggest	VERB
fnp-3050	276	26	that	that	SCONJ
fnp-3050	276	27	both	both	DET
fnp-3050	276	28	pathologies	pathology	NOUN
fnp-3050	276	29	have	have	VERB
fnp-3050	276	30	synergistic	synergistic	ADJ
fnp-3050	276	31	effects	effect	NOUN
fnp-3050	276	32	.	.	PUNCT
fnp-3050	277	1	the	the	DET
fnp-3050	277	2	complex	complex	ADJ
fnp-3050	277	3	aβ	aβ	NOUN
fnp-3050	277	4	-	-	PUNCT
fnp-3050	277	5	tau	tau	NOUN
fnp-3050	277	6	interaction	interaction	NOUN
fnp-3050	277	7	is	be	AUX
fnp-3050	277	8	important	important	ADJ
fnp-3050	277	9	for	for	ADP
fnp-3050	277	10	elucidating	elucidate	VERB
fnp-3050	277	11	disease	disease	NOUN
fnp-3050	277	12	pathogenesis	pathogenesis	NOUN
fnp-3050	277	13	and	and	CCONJ
fnp-3050	277	14	the	the	DET
fnp-3050	277	15	design	design	NOUN
fnp-3050	277	16	of	of	ADP
fnp-3050	277	17	next	next	ADJ
fnp-3050	277	18	-	-	PUNCT
fnp-3050	277	19	generation	generation	NOUN
fnp-3050	277	20	ad	ad	NOUN
fnp-3050	277	21	therapeutical	therapeutical	ADJ
fnp-3050	277	22	trials	trial	NOUN
fnp-3050	277	23	[	[	X
fnp-3050	277	24	153	153	NUM
fnp-3050	277	25	]	]	PUNCT
fnp-3050	277	26	.	.	PUNCT
fnp-3050	278	1	targeting	target	VERB
fnp-3050	278	2	the	the	DET
fnp-3050	278	3	common	common	ADJ
fnp-3050	278	4	epitope	epitope	NOUN
fnp-3050	278	5	could	could	AUX
fnp-3050	278	6	be	be	AUX
fnp-3050	278	7	a	a	DET
fnp-3050	278	8	more	more	ADV
fnp-3050	278	9	effective	effective	ADJ
fnp-3050	278	10	treatment	treatment	NOUN
fnp-3050	278	11	strategy	strategy	NOUN
fnp-3050	278	12	than	than	ADP
fnp-3050	278	13	targeting	target	VERB
fnp-3050	278	14	only	only	ADV
fnp-3050	278	15	aβ	aβ	ADP
fnp-3050	278	16	or	or	CCONJ
fnp-3050	278	17	tau	tau	PROPN
fnp-3050	278	18	alone	alone	ADV
fnp-3050	279	1	[	[	X
fnp-3050	279	2	186	186	NUM
fnp-3050	279	3	]	]	PUNCT
fnp-3050	279	4	.	.	PUNCT
fnp-3050	280	1	mounting	mount	VERB
fnp-3050	280	2	data	datum	NOUN
fnp-3050	280	3	suggest	suggest	VERB
fnp-3050	280	4	that	that	SCONJ
fnp-3050	280	5	the	the	DET
fnp-3050	280	6	prion	prion	NOUN
fnp-3050	280	7	-	-	PUNCT
fnp-3050	280	8	like	like	ADJ
fnp-3050	280	9	spreading	spreading	NOUN
fnp-3050	280	10	of	of	ADP
fnp-3050	280	11	diffusible	diffusible	ADJ
fnp-3050	280	12	oligomers	oligomer	NOUN
fnp-3050	280	13	and	and	CCONJ
fnp-3050	280	14	other	other	ADJ
fnp-3050	280	15	protein	protein	NOUN
fnp-3050	280	16	aggregates	aggregate	NOUN
fnp-3050	280	17	from	from	ADP
fnp-3050	280	18	cell	cell	NOUN
fnp-3050	280	19	to	to	ADP
fnp-3050	280	20	cell	cell	NOUN
fnp-3050	280	21	within	within	ADP
fnp-3050	280	22	the	the	DET
fnp-3050	280	23	brain	brain	NOUN
fnp-3050	280	24	,	,	PUNCT
fnp-3050	280	25	probably	probably	ADV
fnp-3050	280	26	through	through	ADP
fnp-3050	280	27	specific	specific	ADJ
fnp-3050	280	28	neuronal	neuronal	ADJ
fnp-3050	280	29	networks	network	NOUN
fnp-3050	280	30	,	,	PUNCT
fnp-3050	280	31	may	may	AUX
fnp-3050	280	32	contribute	contribute	VERB
fnp-3050	280	33	to	to	ADP
fnp-3050	280	34	ad	ad	NOUN
fnp-3050	280	35	progression	progression	NOUN
fnp-3050	280	36	[	[	X
fnp-3050	280	37	128	128	NUM
fnp-3050	280	38	,	,	PUNCT
fnp-3050	280	39	187	187	NUM
fnp-3050	280	40	]	]	PUNCT
fnp-3050	280	41	.	.	PUNCT
fnp-3050	281	1	app	app	NOUN
fnp-3050	281	2	overexpression	overexpression	NOUN
fnp-3050	281	3	is	be	AUX
fnp-3050	281	4	not	not	PART
fnp-3050	281	5	a	a	DET
fnp-3050	281	6	prerequisite	prerequisite	NOUN
fnp-3050	281	7	for	for	ADP
fnp-3050	281	8	the	the	DET
fnp-3050	281	9	prion	prion	NOUN
fnp-3050	281	10	-	-	PUNCT
fnp-3050	281	11	like	like	ADJ
fnp-3050	281	12	induction	induction	NOUN
fnp-3050	281	13	of	of	ADP
fnp-3050	281	14	cerebral	cerebral	ADJ
fnp-3050	281	15	aβ	aβ	NOUN
fnp-3050	281	16	deposition	deposition	NOUN
fnp-3050	281	17	that	that	PRON
fnp-3050	281	18	may	may	AUX
fnp-3050	281	19	contribute	contribute	VERB
fnp-3050	281	20	to	to	ADP
fnp-3050	281	21	disease	disease	NOUN
fnp-3050	281	22	progression	progression	NOUN
fnp-3050	281	23	in	in	ADP
fnp-3050	281	24	ad	ad	NOUN
fnp-3050	281	25	[	[	X
fnp-3050	281	26	178	178	NUM
fnp-3050	281	27	]	]	PUNCT
fnp-3050	281	28	,	,	PUNCT
fnp-3050	281	29	and	and	CCONJ
fnp-3050	281	30	the	the	DET
fnp-3050	281	31	multiple	multiple	ADJ
fnp-3050	281	32	failures	failure	NOUN
fnp-3050	281	33	of	of	ADP
fnp-3050	281	34	previous	previous	ADJ
fnp-3050	281	35	anti	anti	ADJ
fnp-3050	281	36	-	-	ADJ
fnp-3050	281	37	aβ	aβ	ADJ
fnp-3050	281	38	drugs	drug	NOUN
fnp-3050	281	39	may	may	AUX
fnp-3050	281	40	suggest	suggest	VERB
fnp-3050	281	41	that	that	SCONJ
fnp-3050	281	42	in	in	ADP
fnp-3050	281	43	the	the	DET
fnp-3050	281	44	ad	ad	NOUN
fnp-3050	281	45	brain	brain	NOUN
fnp-3050	281	46	,	,	PUNCT
fnp-3050	281	47	the	the	DET
fnp-3050	281	48	accumulation	accumulation	NOUN
fnp-3050	281	49	of	of	ADP
fnp-3050	281	50	aβ	aβ	PRON
fnp-3050	281	51	could	could	AUX
fnp-3050	281	52	be	be	AUX
fnp-3050	281	53	secondary	secondary	ADJ
fnp-3050	281	54	to	to	ADP
fnp-3050	281	55	an	an	DET
fnp-3050	281	56	unknown	unknown	ADJ
fnp-3050	281	57	'	'	PUNCT
fnp-3050	281	58	initial	initial	ADJ
fnp-3050	281	59	disrupting	disrupt	VERB
fnp-3050	281	60	event	event	NOUN
fnp-3050	281	61	'	'	PUNCT
fnp-3050	282	1	[	[	X
fnp-3050	282	2	188	188	NUM
fnp-3050	282	3	]	]	PUNCT
fnp-3050	282	4	.	.	PUNCT
fnp-3050	283	1	processing	processing	NOUN
fnp-3050	283	2	and	and	CCONJ
fnp-3050	283	3	clearance	clearance	NOUN
fnp-3050	283	4	of	of	ADP
fnp-3050	283	5	aβ	aβ	PRON
fnp-3050	283	6	and	and	CCONJ
fnp-3050	283	7	tau	tau	PROPN
fnp-3050	283	8	could	could	AUX
fnp-3050	283	9	be	be	AUX
fnp-3050	283	10	related	relate	VERB
fnp-3050	283	11	to	to	ADP
fnp-3050	283	12	a	a	DET
fnp-3050	283	13	bidirectional	bidirectional	ADJ
fnp-3050	283	14	relationship	relationship	NOUN
fnp-3050	283	15	between	between	ADP
fnp-3050	283	16	adnc	adnc	ADJ
fnp-3050	283	17	and	and	CCONJ
fnp-3050	283	18	autophagy	autophagy	NOUN
fnp-3050	283	19	[	[	X
fnp-3050	283	20	189	189	NUM
fnp-3050	283	21	]	]	PUNCT
fnp-3050	283	22	.	.	PUNCT
fnp-3050	284	1	seeded	seeded	ADJ
fnp-3050	284	2	templating	templating	NOUN
fnp-3050	284	3	and	and	CCONJ
fnp-3050	284	4	neurotoxicity	neurotoxicity	NOUN
fnp-3050	284	5	are	be	AUX
fnp-3050	284	6	two	two	NUM
fnp-3050	284	7	of	of	ADP
fnp-3050	284	8	the	the	DET
fnp-3050	284	9	most	most	ADV
fnp-3050	284	10	critical	critical	ADJ
fnp-3050	284	11	properties	property	NOUN
fnp-3050	284	12	attributed	attribute	VERB
fnp-3050	284	13	to	to	ADP
fnp-3050	284	14	oligomers	oligomer	NOUN
fnp-3050	284	15	that	that	PRON
fnp-3050	284	16	have	have	AUX
fnp-3050	284	17	been	be	AUX
fnp-3050	284	18	documented	document	VERB
fnp-3050	284	19	for	for	ADP
fnp-3050	284	20	misfolded	misfolde	VERB
fnp-3050	284	21	proteins	protein	NOUN
fnp-3050	284	22	in	in	ADP
fnp-3050	284	23	neurodegeneration	neurodegeneration	NOUN
fnp-3050	284	24	[	[	X
fnp-3050	284	25	190	190	NUM
fnp-3050	284	26	]	]	PUNCT
fnp-3050	284	27	.	.	PUNCT
fnp-3050	285	1	it	it	PRON
fnp-3050	285	2	has	have	AUX
fnp-3050	285	3	been	be	AUX
fnp-3050	285	4	speculated	speculate	VERB
fnp-3050	285	5	that	that	SCONJ
fnp-3050	285	6	cellular	cellular	ADJ
fnp-3050	285	7	prion	prion	NOUN
fnp-3050	285	8	protein	protein	NOUN
fnp-3050	285	9	(	(	PUNCT
fnp-3050	285	10	prpc	prpc	NOUN
fnp-3050	285	11	)	)	PUNCT
fnp-3050	285	12	is	be	AUX
fnp-3050	285	13	a	a	DET
fnp-3050	285	14	critical	critical	ADJ
fnp-3050	285	15	player	player	NOUN
fnp-3050	285	16	in	in	ADP
fnp-3050	285	17	the	the	DET
fnp-3050	285	18	interplay	interplay	NOUN
fnp-3050	285	19	between	between	ADP
fnp-3050	285	20	aβ	aβ	NOUN
fnp-3050	285	21	and	and	CCONJ
fnp-3050	285	22	tau	tau	PROPN
fnp-3050	285	23	propagation	propagation	NOUN
fnp-3050	285	24	in	in	ADP
fnp-3050	285	25	a	a	DET
fnp-3050	285	26	large	large	ADJ
fnp-3050	285	27	group	group	NOUN
fnp-3050	285	28	of	of	ADP
fnp-3050	285	29	ad	ad	NOUN
fnp-3050	285	30	cases	case	NOUN
fnp-3050	285	31	.	.	PUNCT
fnp-3050	286	1	pre	pre	ADJ
fnp-3050	286	2	-	-	ADJ
fnp-3050	286	3	existing	exist	VERB
fnp-3050	286	4	hp	hp	ADJ
fnp-3050	286	5	-	-	PUNCT
fnp-3050	286	6	tau	tau	PROPN
fnp-3050	286	7	pathology	pathology	NOUN
fnp-3050	286	8	interacting	interact	VERB
fnp-3050	286	9	with	with	ADP
fnp-3050	286	10	prpc	prpc	NOUN
fnp-3050	286	11	appears	appear	VERB
fnp-3050	286	12	to	to	PART
fnp-3050	286	13	be	be	AUX
fnp-3050	286	14	a	a	DET
fnp-3050	286	15	prerequisite	prerequisite	NOUN
fnp-3050	286	16	for	for	ADP
fnp-3050	286	17	aβ	aβ	NOUN
fnp-3050	286	18	function	function	NOUN
fnp-3050	286	19	as	as	ADP
fnp-3050	286	20	a	a	DET
fnp-3050	286	21	hp	hp	ADJ
fnp-3050	286	22	-	-	ADJ
fnp-3050	286	23	tau	tau	NOUN
fnp-3050	286	24	pthology	pthology	NOUN
fnp-3050	286	25	acceleration	acceleration	NOUN
fnp-3050	286	26	via	via	ADP
fnp-3050	286	27	prpc	prpc	NOUN
fnp-3050	286	28	[	[	X
fnp-3050	286	29	165	165	NUM
fnp-3050	286	30	]	]	PUNCT
fnp-3050	286	31	.	.	PUNCT
fnp-3050	287	1	toxic	toxic	ADJ
fnp-3050	287	2	tau	tau	PROPN
fnp-3050	287	3	oligomers	oligomer	NOUN
fnp-3050	287	4	(	(	PUNCT
fnp-3050	287	5	tauos	tauos	NOUN
fnp-3050	287	6	)	)	PUNCT
fnp-3050	287	7	and	and	CCONJ
fnp-3050	287	8	toxic	toxic	ADJ
fnp-3050	287	9	oligomeric	oligomeric	ADJ
fnp-3050	287	10	aβ	aβ	NOUN
fnp-3050	287	11	assemblies	assembly	NOUN
fnp-3050	287	12	(	(	PUNCT
fnp-3050	287	13	aos	aos	PROPN
fnp-3050	287	14	)	)	PUNCT
fnp-3050	287	15	have	have	VERB
fnp-3050	287	16	prionoid	prionoid	ADJ
fnp-3050	287	17	characteristics	characteristic	NOUN
fnp-3050	287	18	and	and	CCONJ
fnp-3050	287	19	are	be	AUX
fnp-3050	287	20	responsible	responsible	ADJ
fnp-3050	287	21	for	for	ADP
fnp-3050	287	22	cell	cell	NOUN
fnp-3050	287	23	-	-	PUNCT
fnp-3050	287	24	to	to	ADP
fnp-3050	287	25	-	-	PUNCT
fnp-3050	287	26	cell	cell	NOUN
fnp-3050	287	27	spreading	spread	VERB
fnp-3050	287	28	in	in	ADP
fnp-3050	287	29	the	the	DET
fnp-3050	287	30	brain	brain	NOUN
fnp-3050	287	31	.	.	PUNCT
fnp-3050	288	1	both	both	PRON
fnp-3050	288	2	extraand	extraand	VERB
fnp-3050	288	3	intracellular	intracellular	ADJ
fnp-3050	288	4	aβos	aβos	NOUN
fnp-3050	288	5	and	and	CCONJ
fnp-3050	288	6	tauos	tauos	NOUN
fnp-3050	288	7	(	(	PUNCT
fnp-3050	288	8	not	not	PART
fnp-3050	288	9	nfts	nft	NOUN
fnp-3050	288	10	and	and	CCONJ
fnp-3050	288	11	aps	ap	NOUN
fnp-3050	288	12	)	)	PUNCT
fnp-3050	288	13	may	may	AUX
fnp-3050	288	14	represent	represent	VERB
fnp-3050	288	15	novel	novel	ADJ
fnp-3050	288	16	targets	target	NOUN
fnp-3050	288	17	of	of	ADP
fnp-3050	288	18	ad	ad	NOUN
fnp-3050	288	19	research	research	NOUN
fnp-3050	288	20	and	and	CCONJ
fnp-3050	288	21	therapeutic	therapeutic	ADJ
fnp-3050	288	22	trials	trial	NOUN
fnp-3050	288	23	[	[	X
fnp-3050	288	24	191	191	NUM
fnp-3050	288	25	]	]	PUNCT
fnp-3050	288	26	.	.	PUNCT
fnp-3050	289	1	preventing	prevent	VERB
fnp-3050	289	2	soluble	soluble	ADJ
fnp-3050	289	3	aβo	aβo	NOUN
fnp-3050	289	4	formation	formation	NOUN
fnp-3050	289	5	and	and	CCONJ
fnp-3050	289	6	targeting	target	VERB
fnp-3050	289	7	their	their	PRON
fnp-3050	289	8	n	n	CCONJ
fnp-3050	289	9	-	-	PUNCT
fnp-3050	289	10	terminal	terminal	ADJ
fnp-3050	289	11	residues	residue	NOUN
fnp-3050	289	12	with	with	ADP
fnp-3050	289	13	antibodies	antibody	NOUN
fnp-3050	289	14	could	could	AUX
fnp-3050	289	15	be	be	AUX
fnp-3050	289	16	an	an	DET
fnp-3050	289	17	attractive	attractive	ADJ
fnp-3050	289	18	combined	combined	ADJ
fnp-3050	289	19	therapeutic	therapeutic	ADJ
fnp-3050	289	20	approach	approach	NOUN
fnp-3050	289	21	[	[	X
fnp-3050	289	22	178	178	NUM
fnp-3050	289	23	]	]	PUNCT
fnp-3050	289	24	.	.	PUNCT
fnp-3050	290	1	recent	recent	ADJ
fnp-3050	290	2	studies	study	NOUN
fnp-3050	290	3	found	find	VERB
fnp-3050	290	4	striking	strike	VERB
fnp-3050	290	5	patient	patient	NOUN
fnp-3050	290	6	-	-	PUNCT
fnp-3050	290	7	to	to	ADP
fnp-3050	290	8	-	-	PUNCT
fnp-3050	290	9	patient	patient	NOUN
fnp-3050	290	10	heterogeneity	heterogeneity	NOUN
fnp-3050	290	11	in	in	ADP
fnp-3050	290	12	the	the	DET
fnp-3050	290	13	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-3050	290	14	species	specie	NOUN
fnp-3050	290	15	of	of	ADP
fnp-3050	290	16	soluble	soluble	ADJ
fnp-3050	290	17	oligomeric	oligomeric	ADJ
fnp-3050	290	18	seed	seed	NOUN
fnp-3050	290	19	-	-	PUNCT
fnp-3050	290	20	competent	competent	ADJ
fnp-3050	290	21	tau	tau	NOUN
fnp-3050	290	22	.	.	PUNCT
fnp-3050	291	1	its	its	PRON
fnp-3050	291	2	seeding	seeding	NOUN
fnp-3050	291	3	capacity	capacity	NOUN
fnp-3050	291	4	correlates	correlate	VERB
fnp-3050	291	5	with	with	ADP
fnp-3050	291	6	the	the	DET
fnp-3050	291	7	aggressiveness	aggressiveness	NOUN
fnp-3050	291	8	of	of	ADP
fnp-3050	291	9	the	the	DET
fnp-3050	291	10	clinical	clinical	ADJ
fnp-3050	291	11	disease	disease	NOUN
fnp-3050	291	12	,	,	PUNCT
fnp-3050	291	13	and	and	CCONJ
fnp-3050	291	14	some	some	DET
fnp-3050	291	15	post	post	ADJ
fnp-3050	291	16	-	-	ADJ
fnp-3050	291	17	translational	translational	ADJ
fnp-3050	291	18	modification	modification	NOUN
fnp-3050	291	19	sites	site	NOUN
fnp-3050	291	20	appeared	appear	VERB
fnp-3050	291	21	to	to	PART
fnp-3050	291	22	be	be	AUX
fnp-3050	291	23	associated	associate	VERB
fnp-3050	291	24	with	with	ADP
fnp-3050	291	25	both	both	CCONJ
fnp-3050	291	26	seeding	seed	VERB
fnp-3050	291	27	activity	activity	NOUN
fnp-3050	291	28	and	and	CCONJ
fnp-3050	291	29	worse	bad	ADJ
fnp-3050	291	30	clinical	clinical	ADJ
fnp-3050	291	31	outcomes	outcome	NOUN
fnp-3050	291	32	,	,	PUNCT
fnp-3050	291	33	suggesting	suggest	VERB
fnp-3050	291	34	that	that	SCONJ
fnp-3050	291	35	different	different	ADJ
fnp-3050	291	36	individuals	individual	NOUN
fnp-3050	291	37	with	with	ADP
fnp-3050	291	38	“	"	PUNCT
fnp-3050	291	39	typical	typical	ADJ
fnp-3050	291	40	”	"	PUNCT
fnp-3050	291	41	ad	ad	NOUN
fnp-3050	291	42	have	have	VERB
fnp-3050	291	43	distinct	distinct	ADJ
fnp-3050	291	44	biochemical	biochemical	ADJ
fnp-3050	291	45	features	feature	NOUN
fnp-3050	291	46	of	of	ADP
fnp-3050	291	47	tau	tau	PROPN
fnp-3050	291	48	that	that	PRON
fnp-3050	291	49	correlated	correlate	VERB
fnp-3050	291	50	with	with	ADP
fnp-3050	291	51	differences	difference	NOUN
fnp-3050	291	52	in	in	ADP
fnp-3050	291	53	the	the	DET
fnp-3050	291	54	aggressiveness	aggressiveness	NOUN
fnp-3050	291	55	of	of	ADP
fnp-3050	291	56	clinical	clinical	ADJ
fnp-3050	291	57	course	course	NOUN
fnp-3050	291	58	[	[	X
fnp-3050	291	59	192	192	NUM
fnp-3050	291	60	]	]	PUNCT
fnp-3050	291	61	,	,	PUNCT
fnp-3050	291	62	supporting	support	VERB
fnp-3050	291	63	an	an	DET
fnp-3050	291	64	important	important	ADJ
fnp-3050	291	65	causal	causal	ADJ
fnp-3050	291	66	role	role	NOUN
fnp-3050	291	67	of	of	ADP
fnp-3050	291	68	tau	tau	PROPN
fnp-3050	291	69	as	as	ADP
fnp-3050	291	70	a	a	DET
fnp-3050	291	71	driver	driver	NOUN
fnp-3050	291	72	of	of	ADP
fnp-3050	291	73	clinical	clinical	ADJ
fnp-3050	291	74	dysfunction	dysfunction	NOUN
fnp-3050	291	75	in	in	ADP
fnp-3050	291	76	ad	ad	NOUN
fnp-3050	291	77	[	[	X
fnp-3050	291	78	193	193	NUM
fnp-3050	291	79	]	]	PUNCT
fnp-3050	291	80	.	.	PUNCT
fnp-3050	292	1	the	the	DET
fnp-3050	292	2	synergism	synergism	NOUN
fnp-3050	292	3	between	between	ADP
fnp-3050	292	4	aβ	aβ	ADP
fnp-3050	292	5	deposition	deposition	NOUN
fnp-3050	292	6	,	,	PUNCT
fnp-3050	292	7	nft	nft	PROPN
fnp-3050	292	8	neurodegeneration	neurodegeneration	NOUN
fnp-3050	292	9	,	,	PUNCT
fnp-3050	292	10	and	and	CCONJ
fnp-3050	292	11	caa	caa	NOUN
fnp-3050	292	12	may	may	AUX
fnp-3050	292	13	be	be	AUX
fnp-3050	292	14	a	a	DET
fnp-3050	292	15	better	well	ADJ
fnp-3050	292	16	predictor	predictor	NOUN
fnp-3050	292	17	of	of	ADP
fnp-3050	292	18	cognitive	cognitive	ADJ
fnp-3050	292	19	decline	decline	NOUN
fnp-3050	292	20	or	or	CCONJ
fnp-3050	292	21	disease	disease	NOUN
fnp-3050	292	22	progression	progression	NOUN
fnp-3050	292	23	than	than	ADP
fnp-3050	292	24	either	either	DET
fnp-3050	292	25	pathology	pathology	NOUN
fnp-3050	292	26	alone	alone	ADV
fnp-3050	292	27	[	[	X
fnp-3050	292	28	194	194	NUM
fnp-3050	292	29	]	]	PUNCT
fnp-3050	292	30	(	(	PUNCT
fnp-3050	292	31	fig	fig	NOUN
fnp-3050	292	32	.	.	PUNCT
fnp-3050	293	1	7	7	NUM
fnp-3050	293	2	)	)	PUNCT
fnp-3050	293	3	.	.	PUNCT
fnp-3050	294	1	figure	figure	VERB
fnp-3050	294	2	7	7	NUM
fnp-3050	294	3	.	.	PUNCT
fnp-3050	294	4	staging	staging	NOUN
fnp-3050	294	5	of	of	ADP
fnp-3050	294	6	aβ	aβ	PROPN
fnp-3050	294	7	,	,	PUNCT
fnp-3050	294	8	nft	nft	PROPN
fnp-3050	294	9	,	,	PUNCT
fnp-3050	294	10	and	and	CCONJ
fnp-3050	294	11	caa	caa	NOUN
fnp-3050	294	12	in	in	ADP
fnp-3050	294	13	non	non	ADJ
fnp-3050	294	14	-	-	ADJ
fnp-3050	294	15	demented	demented	ADJ
fnp-3050	294	16	(	(	PUNCT
fnp-3050	294	17	pre	pre	NOUN
fnp-3050	294	18	-	-	NOUN
fnp-3050	294	19	ad	ad	NOUN
fnp-3050	294	20	)	)	PUNCT
fnp-3050	294	21	and	and	CCONJ
fnp-3050	294	22	demented	demented	ADJ
fnp-3050	294	23	ad	ad	NOUN
fnp-3050	294	24	patients	patient	NOUN
fnp-3050	294	25	.	.	PUNCT
fnp-3050	295	1	from	from	ADP
fnp-3050	295	2	[	[	X
fnp-3050	295	3	195	195	NUM
fnp-3050	295	4	]	]	PUNCT
fnp-3050	295	5	.	.	PUNCT
fnp-3050	296	1	2.9	2.9	NUM
fnp-3050	296	2	.	.	PUNCT
fnp-3050	297	1	synaptic	synaptic	ADJ
fnp-3050	297	2	and	and	CCONJ
fnp-3050	297	3	neuronal	neuronal	ADJ
fnp-3050	297	4	loss	loss	NOUN
fnp-3050	297	5	essential	essential	ADJ
fnp-3050	297	6	neuropathological	neuropathological	ADJ
fnp-3050	297	7	features	feature	NOUN
fnp-3050	297	8	of	of	ADP
fnp-3050	297	9	ad	ad	NOUN
fnp-3050	297	10	are	be	AUX
fnp-3050	297	11	loss	loss	NOUN
fnp-3050	297	12	of	of	ADP
fnp-3050	297	13	synapses	synapsis	NOUN
fnp-3050	297	14	and	and	CCONJ
fnp-3050	297	15	selected	select	VERB
fnp-3050	297	16	neuronal	neuronal	ADJ
fnp-3050	297	17	cells	cell	NOUN
fnp-3050	297	18	(	(	PUNCT
fnp-3050	297	19	20	20	NUM
fnp-3050	297	20	-	-	SYM
fnp-3050	297	21	40	40	NUM
fnp-3050	297	22	%	%	NOUN
fnp-3050	297	23	in	in	ADP
fnp-3050	297	24	neocortex	neocortex	NOUN
fnp-3050	297	25	and	and	CCONJ
fnp-3050	297	26	25	25	NUM
fnp-3050	297	27	-	-	SYM
fnp-3050	297	28	65	65	NUM
fnp-3050	297	29	%	%	NOUN
fnp-3050	297	30	in	in	ADP
fnp-3050	297	31	hippocampus	hippocampus	NOUN
fnp-3050	297	32	)	)	PUNCT
fnp-3050	297	33	as	as	ADP
fnp-3050	297	34	the	the	DET
fnp-3050	297	35	main	main	ADJ
fnp-3050	297	36	pathological	pathological	ADJ
fnp-3050	297	37	substrate	substrate	NOUN
fnp-3050	297	38	of	of	ADP
fnp-3050	297	39	cortical	cortical	ADJ
fnp-3050	297	40	atrophy	atrophy	NOUN
fnp-3050	297	41	.	.	PUNCT
fnp-3050	298	1	its	its	PRON
fnp-3050	298	2	regional	regional	ADJ
fnp-3050	298	3	and	and	CCONJ
fnp-3050	298	4	laminar	laminar	ADJ
fnp-3050	298	5	pattern	pattern	NOUN
fnp-3050	298	6	parallels	parallel	VERB
fnp-3050	298	7	the	the	DET
fnp-3050	298	8	distribution	distribution	NOUN
fnp-3050	298	9	of	of	ADP
fnp-3050	298	10	nfts	nft	NOUN
fnp-3050	298	11	and	and	CCONJ
fnp-3050	298	12	has	have	AUX
fnp-3050	298	13	been	be	AUX
fnp-3050	298	14	suggested	suggest	VERB
fnp-3050	298	15	to	to	PART
fnp-3050	298	16	be	be	AUX
fnp-3050	298	17	a	a	DET
fnp-3050	298	18	better	well	ADJ
fnp-3050	298	19	correlate	correlate	NOUN
fnp-3050	298	20	of	of	ADP
fnp-3050	298	21	cognitive	cognitive	ADJ
fnp-3050	298	22	deficits	deficit	NOUN
fnp-3050	298	23	than	than	ADP
fnp-3050	298	24	the	the	DET
fnp-3050	298	25	aβ	aβ	NOUN
fnp-3050	298	26	burden	burden	NOUN
fnp-3050	298	27	[	[	X
fnp-3050	298	28	139	139	NUM
fnp-3050	298	29	,	,	PUNCT
fnp-3050	298	30	196	196	NUM
fnp-3050	298	31	]	]	PUNCT
fnp-3050	298	32	.	.	PUNCT
fnp-3050	299	1	little	little	ADJ
fnp-3050	299	2	is	be	AUX
fnp-3050	299	3	known	know	VERB
fnp-3050	299	4	about	about	ADP
fnp-3050	299	5	the	the	DET
fnp-3050	299	6	molecular	molecular	ADJ
fnp-3050	299	7	basis	basis	NOUN
fnp-3050	299	8	of	of	ADP
fnp-3050	299	9	selective	selective	ADJ
fnp-3050	299	10	neuronal	neuronal	ADJ
fnp-3050	299	11	vulnerability	vulnerability	NOUN
fnp-3050	299	12	in	in	ADP
fnp-3050	299	13	ad	ad	NOUN
fnp-3050	299	14	and	and	CCONJ
fnp-3050	299	15	the	the	DET
fnp-3050	299	16	molecular	molecular	ADJ
fnp-3050	299	17	pathways	pathway	NOUN
fnp-3050	299	18	that	that	PRON
fnp-3050	299	19	lead	lead	VERB
fnp-3050	299	20	to	to	ADP
fnp-3050	299	21	neurodegeneration	neurodegeneration	NOUN
fnp-3050	299	22	,	,	PUNCT
fnp-3050	299	23	a	a	DET
fnp-3050	299	24	key	key	ADJ
fnp-3050	299	25	characteristic	characteristic	NOUN
fnp-3050	299	26	of	of	ADP
fnp-3050	299	27	the	the	DET
fnp-3050	299	28	disease	disease	NOUN
fnp-3050	299	29	.	.	PUNCT
fnp-3050	300	1	it	it	PRON
fnp-3050	300	2	is	be	AUX
fnp-3050	300	3	the	the	DET
fnp-3050	300	4	result	result	NOUN
fnp-3050	300	5	of	of	ADP
fnp-3050	300	6	multiple	multiple	ADJ
fnp-3050	300	7	molecular	molecular	ADJ
fnp-3050	300	8	changes	change	NOUN
fnp-3050	300	9	of	of	ADP
fnp-3050	300	10	interacting	interact	VERB
fnp-3050	300	11	genes	gene	NOUN
fnp-3050	300	12	and	and	CCONJ
fnp-3050	300	13	pathways	pathway	NOUN
fnp-3050	300	14	within	within	ADP
fnp-3050	300	15	vulnerable	vulnerable	ADJ
fnp-3050	300	16	neurons	neuron	NOUN
fnp-3050	300	17	[	[	X
fnp-3050	300	18	25	25	NUM
fnp-3050	300	19	]	]	PUNCT
fnp-3050	300	20	.	.	PUNCT
fnp-3050	301	1	the	the	DET
fnp-3050	301	2	relationship	relationship	NOUN
fnp-3050	301	3	between	between	ADP
fnp-3050	301	4	cellular	cellular	ADJ
fnp-3050	301	5	senescence	senescence	NOUN
fnp-3050	301	6	in	in	ADP
fnp-3050	301	7	the	the	DET
fnp-3050	301	8	context	context	NOUN
fnp-3050	301	9	of	of	ADP
fnp-3050	301	10	aging	aging	NOUN
fnp-3050	301	11	and	and	CCONJ
fnp-3050	301	12	ad	ad	NOUN
fnp-3050	301	13	have	have	AUX
fnp-3050	301	14	been	be	AUX
fnp-3050	301	15	reviewed	review	VERB
fnp-3050	301	16	recently	recently	ADV
fnp-3050	301	17	[	[	X
fnp-3050	301	18	197	197	NUM
fnp-3050	301	19	]	]	PUNCT
fnp-3050	301	20	.	.	PUNCT
fnp-3050	302	1	age	age	NOUN
fnp-3050	302	2	-	-	PUNCT
fnp-3050	302	3	related	relate	VERB
fnp-3050	302	4	intraneuronal	intraneuronal	ADJ
fnp-3050	302	5	aggregation	aggregation	NOUN
fnp-3050	302	6	of	of	ADP
fnp-3050	302	7	aβ	aβ	NOUN
fnp-3050	302	8	is	be	AUX
fnp-3050	302	9	colocalized	colocalize	VERB
fnp-3050	302	10	with	with	ADP
fnp-3050	302	11	mitochondria	mitochondria	NOUN
fnp-3050	302	12	and	and	CCONJ
fnp-3050	302	13	endosomes	endosome	NOUN
fnp-3050	302	14	and	and	CCONJ
fnp-3050	302	15	less	less	ADV
fnp-3050	302	16	so	so	ADV
fnp-3050	302	17	with	with	ADP
fnp-3050	302	18	lysosomes	lysosome	NOUN
fnp-3050	302	19	and	and	CCONJ
fnp-3050	302	20	autophagosomes	autophagosome	NOUN
fnp-3050	302	21	.	.	PUNCT
fnp-3050	303	1	understanding	understand	VERB
fnp-3050	303	2	age	age	NOUN
fnp-3050	303	3	-	-	PUNCT
fnp-3050	303	4	related	relate	VERB
fnp-3050	303	5	changes	change	NOUN
fnp-3050	303	6	in	in	ADP
fnp-3050	303	7	intraneuronal	intraneuronal	ADJ
fnp-3050	303	8	aβ	aβ	PRON
fnp-3050	303	9	may	may	AUX
fnp-3050	303	10	lead	lead	VERB
fnp-3050	303	11	to	to	ADP
fnp-3050	303	12	application	application	NOUN
fnp-3050	303	13	of	of	ADP
fnp-3050	303	14	countermeasures	countermeasure	NOUN
fnp-3050	303	15	to	to	PART
fnp-3050	303	16	prolong	prolong	VERB
fnp-3050	303	17	dementia	dementia	NOUN
fnp-3050	303	18	-	-	PUNCT
fnp-3050	303	19	free	free	ADJ
fnp-3050	303	20	health	health	NOUN
fnp-3050	303	21	span	span	NOUN
fnp-3050	303	22	[	[	X
fnp-3050	303	23	198	198	NUM
fnp-3050	303	24	]	]	PUNCT
fnp-3050	303	25	.	.	PUNCT
fnp-3050	304	1	the	the	DET
fnp-3050	304	2	intraneuronal	intraneuronal	ADJ
fnp-3050	304	3	accumulation	accumulation	NOUN
fnp-3050	304	4	of	of	ADP
fnp-3050	304	5	aβ	aβ	PRON
fnp-3050	304	6	may	may	AUX
fnp-3050	304	7	involve	involve	VERB
fnp-3050	304	8	synaptic	synaptic	ADJ
fnp-3050	304	9	dysfunction	dysfunction	NOUN
fnp-3050	304	10	and	and	CCONJ
fnp-3050	304	11	the	the	DET
fnp-3050	304	12	formation	formation	NOUN
fnp-3050	304	13	of	of	ADP
fnp-3050	304	14	aps	ap	NOUN
fnp-3050	304	15	in	in	ADP
fnp-3050	304	16	ad	ad	NOUN
fnp-3050	304	17	;	;	PUNCT
fnp-3050	304	18	intraneuronal	intraneuronal	ADJ
fnp-3050	304	19	aβ-42	aβ-42	ADV
fnp-3050	304	20	has	have	AUX
fnp-3050	304	21	been	be	AUX
fnp-3050	304	22	reported	report	VERB
fnp-3050	304	23	to	to	PART
fnp-3050	304	24	disrupt	disrupt	VERB
fnp-3050	304	25	the	the	DET
fnp-3050	304	26	normal	normal	ADJ
fnp-3050	304	27	cytoarchitecture	cytoarchitecture	NOUN
fnp-3050	304	28	of	of	ADP
fnp-3050	304	29	neurites	neurite	NOUN
fnp-3050	304	30	.	.	PUNCT
fnp-3050	305	1	recent	recent	ADJ
fnp-3050	305	2	studies	study	NOUN
fnp-3050	305	3	indicate	indicate	VERB
fnp-3050	305	4	that	that	SCONJ
fnp-3050	305	5	in	in	ADP
fnp-3050	305	6	ad	ad	NOUN
fnp-3050	305	7	,	,	PUNCT
fnp-3050	305	8	vulnerable	vulnerable	ADJ
fnp-3050	305	9	-	-	PUNCT
fnp-3050	305	10	neuron	neuron	NOUN
fnp-3050	305	11	-	-	PUNCT
fnp-3050	305	12	specific	specific	ADJ
fnp-3050	305	13	dysregulation	dysregulation	NOUN
fnp-3050	305	14	of	of	ADP
fnp-3050	305	15	polypyrimidine	polypyrimidine	ADJ
fnp-3050	305	16	tract	tract	NOUN
fnp-3050	305	17	binding	bind	VERB
fnp-3050	305	18	protein	protein	NOUN
fnp-3050	305	19	(	(	PUNCT
fnp-3050	305	20	ptb	ptb	PROPN
fnp-3050	305	21	)	)	PUNCT
fnp-3050	305	22	(	(	PUNCT
fnp-3050	305	23	ncbi	ncbi	PROPN
fnp-3050	305	24	gene	gene	PROPN
fnp-3050	305	25	i	i	PROPN
fnp-3050	305	26	d	d	PROPN
fnp-3050	305	27	5725	5725	NUM
fnp-3050	305	28	)	)	PUNCT
fnp-3050	305	29	,	,	PUNCT
fnp-3050	305	30	a	a	DET
fnp-3050	305	31	regulator	regulator	NOUN
fnp-3050	305	32	of	of	ADP
fnp-3050	305	33	alternative	alternative	ADJ
fnp-3050	305	34	splicing	splicing	NOUN
fnp-3050	305	35	[	[	X
fnp-3050	305	36	199	199	NUM
fnp-3050	305	37	]	]	PUNCT
fnp-3050	305	38	,	,	PUNCT
fnp-3050	305	39	is	be	AUX
fnp-3050	305	40	the	the	DET
fnp-3050	305	41	protein	protein	NOUN
fnp-3050	305	42	most	most	ADV
fnp-3050	305	43	highly	highly	ADV
fnp-3050	305	44	correlated	correlate	VERB
fnp-3050	305	45	to	to	ADP
fnp-3050	305	46	tau	tau	PROPN
fnp-3050	305	47	in	in	ADP
fnp-3050	305	48	the	the	DET
fnp-3050	305	49	principal	principal	ADJ
fnp-3050	305	50	neurons	neuron	NOUN
fnp-3050	305	51	of	of	ADP
fnp-3050	305	52	the	the	DET
fnp-3050	305	53	entorhinal	entorhinal	ADJ
fnp-3050	305	54	cortex	cortex	NOUN
fnp-3050	305	55	layer	layer	NOUN
fnp-3050	305	56	ii	ii	PROPN
fnp-3050	305	57	(	(	PUNCT
fnp-3050	305	58	ec	ec	PROPN
fnp-3050	305	59	ii	ii	PROPN
fnp-3050	305	60	)	)	PUNCT
fnp-3050	305	61	.	.	PUNCT
fnp-3050	306	1	ptb	ptb	PROPN
fnp-3050	306	2	could	could	AUX
fnp-3050	306	3	precipitate	precipitate	VERB
fnp-3050	306	4	a	a	DET
fnp-3050	306	5	3r/4r	3r/4r	NUM
fnp-3050	306	6	tau	tau	NOUN
fnp-3050	306	7	imbalance	imbalance	NOUN
fnp-3050	306	8	in	in	ADP
fnp-3050	306	9	these	these	DET
fnp-3050	306	10	neurons	neuron	NOUN
fnp-3050	306	11	and	and	CCONJ
fnp-3050	306	12	explain	explain	VERB
fnp-3050	306	13	the	the	DET
fnp-3050	306	14	premature	premature	ADJ
fnp-3050	306	15	accumulation	accumulation	NOUN
fnp-3050	306	16	of	of	ADP
fnp-3050	306	17	nfts	nft	NOUN
fnp-3050	306	18	,	,	PUNCT
fnp-3050	306	19	thus	thus	ADV
fnp-3050	306	20	explaining	explain	VERB
fnp-3050	306	21	the	the	DET
fnp-3050	306	22	vulnerability	vulnerability	NOUN
fnp-3050	306	23	of	of	ADP
fnp-3050	306	24	ec	ec	PROPN
fnp-3050	306	25	ii	ii	PROPN
fnp-3050	306	26	neurons	neuron	NOUN
fnp-3050	306	27	[	[	X
fnp-3050	306	28	25	25	NUM
fnp-3050	306	29	]	]	PUNCT
fnp-3050	306	30	.	.	PUNCT
fnp-3050	307	1	the	the	DET
fnp-3050	307	2	neurotoxic	neurotoxic	ADJ
fnp-3050	307	3	effect	effect	NOUN
fnp-3050	307	4	of	of	ADP
fnp-3050	307	5	astrocyte	astrocyte	NOUN
fnp-3050	307	6	-	-	PUNCT
fnp-3050	307	7	derived	derive	VERB
fnp-3050	307	8	exosomes	exosome	NOUN
fnp-3050	307	9	(	(	PUNCT
fnp-3050	307	10	ade	ade	PROPN
fnp-3050	307	11	)	)	PUNCT
fnp-3050	307	12	is	be	AUX
fnp-3050	307	13	evident	evident	ADJ
fnp-3050	307	14	with	with	ADP
fnp-3050	307	15	the	the	DET
fnp-3050	307	16	overlap	overlap	NOUN
fnp-3050	307	17	of	of	ADP
fnp-3050	307	18	ap	ap	PROPN
fnp-3050	307	19	density	density	NOUN
fnp-3050	307	20	and	and	CCONJ
fnp-3050	307	21	c3/4	c3/4	NOUN
fnp-3050	307	22	fragments	fragment	NOUN
fnp-3050	307	23	(	(	PUNCT
fnp-3050	307	24	complement	complement	NOUN
fnp-3050	307	25	factors	factor	NOUN
fnp-3050	307	26	)	)	PUNCT
fnp-3050	307	27	observed	observe	VERB
fnp-3050	307	28	in	in	ADP
fnp-3050	307	29	early	early	ADJ
fnp-3050	307	30	ad	ad	NOUN
fnp-3050	308	1	[	[	X
fnp-3050	308	2	200	200	NUM
fnp-3050	308	3	]	]	PUNCT
fnp-3050	308	4	.	.	PUNCT
fnp-3050	309	1	although	although	SCONJ
fnp-3050	309	2	tangle	tangle	NOUN
fnp-3050	309	3	-	-	PUNCT
fnp-3050	309	4	bearing	bear	VERB
fnp-3050	309	5	neurons	neuron	NOUN
fnp-3050	309	6	can	can	AUX
fnp-3050	309	7	be	be	AUX
fnp-3050	309	8	long	long	ADV
fnp-3050	309	9	lasting	last	VERB
fnp-3050	309	10	in	in	ADP
fnp-3050	309	11	regions	region	NOUN
fnp-3050	309	12	where	where	SCONJ
fnp-3050	309	13	nfts	nft	NOUN
fnp-3050	309	14	occur	occur	VERB
fnp-3050	309	15	at	at	ADP
fnp-3050	309	16	a	a	DET
fnp-3050	309	17	presymptomatic	presymptomatic	ADJ
fnp-3050	309	18	stage	stage	NOUN
fnp-3050	309	19	,	,	PUNCT
fnp-3050	309	20	neuronal	neuronal	ADJ
fnp-3050	309	21	loss	loss	NOUN
fnp-3050	309	22	occurs	occur	VERB
fnp-3050	309	23	early	early	ADV
fnp-3050	309	24	in	in	ADP
fnp-3050	309	25	the	the	DET
fnp-3050	309	26	course	course	NOUN
fnp-3050	309	27	of	of	ADP
fnp-3050	309	28	the	the	DET
fnp-3050	309	29	symptomatic	symptomatic	ADJ
fnp-3050	309	30	disease	disease	NOUN
fnp-3050	309	31	[	[	X
fnp-3050	309	32	201	201	NUM
fnp-3050	309	33	]	]	PUNCT
fnp-3050	309	34	.	.	PUNCT
fnp-3050	310	1	two	two	NUM
fnp-3050	310	2	mechanisms	mechanism	NOUN
fnp-3050	310	3	of	of	ADP
fnp-3050	310	4	neuronal	neuronal	ADJ
fnp-3050	310	5	death	death	NOUN
fnp-3050	310	6	in	in	ADP
fnp-3050	310	7	ad	ad	NOUN
fnp-3050	310	8	have	have	AUX
fnp-3050	310	9	been	be	AUX
fnp-3050	310	10	discussed	discuss	VERB
fnp-3050	310	11	:	:	PUNCT
fnp-3050	310	12	one	one	NUM
fnp-3050	310	13	affecting	affect	VERB
fnp-3050	310	14	tangle	tangle	NOUN
fnp-3050	310	15	-	-	PUNCT
fnp-3050	310	16	bearing	bear	VERB
fnp-3050	310	17	neurons	neuron	NOUN
fnp-3050	310	18	that	that	PRON
fnp-3050	310	19	will	will	AUX
fnp-3050	310	20	lead	lead	VERB
fnp-3050	310	21	to	to	PART
fnp-3050	310	22	ghost	ghost	VERB
fnp-3050	310	23	extracellular	extracellular	ADJ
fnp-3050	310	24	tangles	tangle	NOUN
fnp-3050	310	25	,	,	PUNCT
fnp-3050	310	26	another	another	DET
fnp-3050	310	27	affecting	affect	VERB
fnp-3050	310	28	tangle	tangle	NOUN
fnp-3050	310	29	-	-	PUNCT
fnp-3050	310	30	free	free	ADJ
fnp-3050	310	31	neurons	neuron	NOUN
fnp-3050	310	32	,	,	PUNCT
fnp-3050	310	33	at	at	ADP
fnp-3050	310	34	least	least	ADJ
fnp-3050	310	35	in	in	ADP
fnp-3050	310	36	part	part	NOUN
fnp-3050	310	37	by	by	ADP
fnp-3050	310	38	apoptosis	apoptosis	NOUN
fnp-3050	310	39	[	[	X
fnp-3050	310	40	202	202	NUM
fnp-3050	310	41	-	-	SYM
fnp-3050	310	42	204	204	NUM
fnp-3050	310	43	]	]	PUNCT
fnp-3050	310	44	.	.	PUNCT
fnp-3050	311	1	inflammation	inflammation	NOUN
fnp-3050	311	2	-	-	PUNCT
fnp-3050	311	3	induced	induce	VERB
fnp-3050	311	4	hyperphosphorylation	hyperphosphorylation	NOUN
fnp-3050	311	5	of	of	ADP
fnp-3050	311	6	tau	tau	PROPN
fnp-3050	311	7	destabilizes	destabilize	VERB
fnp-3050	311	8	the	the	DET
fnp-3050	311	9	microtubule	microtubule	NOUN
fnp-3050	311	10	-	-	PUNCT
fnp-3050	311	11	actin	actin	NOUN
fnp-3050	311	12	network	network	NOUN
fnp-3050	311	13	and	and	CCONJ
fnp-3050	311	14	impairs	impair	VERB
fnp-3050	311	15	axonal	axonal	ADJ
fnp-3050	311	16	transport	transport	NOUN
fnp-3050	311	17	and	and	CCONJ
fnp-3050	311	18	disturbs	disturb	VERB
fnp-3050	311	19	energy	energy	NOUN
fnp-3050	311	20	metabolism	metabolism	NOUN
fnp-3050	311	21	in	in	ADP
fnp-3050	311	22	the	the	DET
fnp-3050	311	23	axon	axon	NOUN
fnp-3050	311	24	,	,	PUNCT
fnp-3050	311	25	inducing	induce	VERB
fnp-3050	311	26	further	further	ADJ
fnp-3050	311	27	tau	tau	PROPN
fnp-3050	311	28	phosphorylation	phosphorylation	NOUN
fnp-3050	311	29	.	.	PUNCT
fnp-3050	312	1	accumulating	accumulate	VERB
fnp-3050	312	2	data	datum	NOUN
fnp-3050	312	3	point	point	NOUN
fnp-3050	312	4	to	to	ADP
fnp-3050	312	5	the	the	DET
fnp-3050	312	6	fact	fact	NOUN
fnp-3050	312	7	that	that	SCONJ
fnp-3050	312	8	this	this	PRON
fnp-3050	312	9	facilitates	facilitate	VERB
fnp-3050	312	10	the	the	DET
fnp-3050	312	11	formation	formation	NOUN
fnp-3050	312	12	of	of	ADP
fnp-3050	312	13	phfs	phfs	ADJ
fnp-3050	312	14	,	,	PUNCT
fnp-3050	312	15	further	far	ADV
fnp-3050	312	16	impairs	impair	VERB
fnp-3050	312	17	axonal	axonal	ADJ
fnp-3050	312	18	transport	transport	NOUN
fnp-3050	312	19	leading	lead	VERB
fnp-3050	312	20	to	to	ADP
fnp-3050	312	21	complete	complete	ADJ
fnp-3050	312	22	blockage	blockage	NOUN
fnp-3050	312	23	and	and	CCONJ
fnp-3050	312	24	axonal	axonal	ADJ
fnp-3050	312	25	leakage	leakage	NOUN
fnp-3050	312	26	,	,	PUNCT
fnp-3050	312	27	and	and	CCONJ
fnp-3050	312	28	induces	induce	VERB
fnp-3050	312	29	loss	loss	NOUN
fnp-3050	312	30	of	of	ADP
fnp-3050	312	31	synaptic	synaptic	ADJ
fnp-3050	312	32	contacts	contact	NOUN
fnp-3050	312	33	promoting	promote	VERB
fnp-3050	312	34	activation	activation	NOUN
fnp-3050	312	35	of	of	ADP
fnp-3050	312	36	microglia	microglia	ADJ
fnp-3050	312	37	and	and	CCONJ
fnp-3050	312	38	reactive	reactive	ADJ
fnp-3050	312	39	astrogliosis	astrogliosis	NOUN
fnp-3050	312	40	[	[	X
fnp-3050	312	41	56	56	NUM
fnp-3050	312	42	]	]	PUNCT
fnp-3050	312	43	.	.	PUNCT
fnp-3050	313	1	microglia	microglia	NOUN
fnp-3050	313	2	have	have	AUX
fnp-3050	313	3	been	be	AUX
fnp-3050	313	4	shown	show	VERB
fnp-3050	313	5	to	to	PART
fnp-3050	313	6	instigate	instigate	VERB
fnp-3050	313	7	tau	tau	PROPN
fnp-3050	313	8	pathology	pathology	NOUN
fnp-3050	313	9	in	in	ADP
fnp-3050	313	10	diverse	diverse	ADJ
fnp-3050	313	11	ways	way	NOUN
fnp-3050	313	12	,	,	PUNCT
fnp-3050	313	13	inducing	induce	VERB
fnp-3050	313	14	tau	tau	NOUN
fnp-3050	313	15	aggregation	aggregation	NOUN
fnp-3050	313	16	by	by	ADP
fnp-3050	313	17	proinflammatory	proinflammatory	ADJ
fnp-3050	313	18	cytokine	cytokine	NOUN
fnp-3050	313	19	release	release	NOUN
fnp-3050	313	20	[	[	X
fnp-3050	313	21	205	205	NUM
fnp-3050	313	22	,	,	PUNCT
fnp-3050	313	23	206	206	NUM
fnp-3050	313	24	]	]	PUNCT
fnp-3050	313	25	,	,	PUNCT
fnp-3050	313	26	and	and	CCONJ
fnp-3050	313	27	spreading	spread	VERB
fnp-3050	313	28	hp	hp	ADJ
fnp-3050	313	29	-	-	PUNCT
fnp-3050	313	30	tau	tau	NOUN
fnp-3050	313	31	oligomers	oligomer	NOUN
fnp-3050	313	32	or	or	CCONJ
fnp-3050	313	33	nfts	nft	NOUN
fnp-3050	313	34	through	through	ADP
fnp-3050	313	35	exosome	exosome	PROPN
fnp-3050	313	36	secretion	secretion	NOUN
fnp-3050	313	37	[	[	X
fnp-3050	313	38	130	130	NUM
fnp-3050	313	39	]	]	PUNCT
fnp-3050	313	40	.	.	PUNCT
fnp-3050	314	1	synaptic	synaptic	ADJ
fnp-3050	314	2	loss	loss	NOUN
fnp-3050	314	3	that	that	PRON
fnp-3050	314	4	is	be	AUX
fnp-3050	314	5	possibly	possibly	ADV
fnp-3050	314	6	driven	drive	VERB
fnp-3050	314	7	by	by	ADP
fnp-3050	314	8	aβ	aβ	PRON
fnp-3050	314	9	and	and	CCONJ
fnp-3050	314	10	tau	tau	PROPN
fnp-3050	314	11	pathology	pathology	NOUN
fnp-3050	314	12	has	have	AUX
fnp-3050	314	13	been	be	AUX
fnp-3050	314	14	suggested	suggest	VERB
fnp-3050	314	15	to	to	PART
fnp-3050	314	16	precede	precede	VERB
fnp-3050	314	17	neuronal	neuronal	ADJ
fnp-3050	314	18	loss	loss	NOUN
fnp-3050	314	19	[	[	X
fnp-3050	314	20	207	207	NUM
fnp-3050	314	21	]	]	PUNCT
fnp-3050	314	22	.	.	PUNCT
fnp-3050	315	1	synapses	synapsis	NOUN
fnp-3050	315	2	are	be	AUX
fnp-3050	315	3	present	present	ADJ
fnp-3050	315	4	in	in	ADP
fnp-3050	315	5	aps	ap	NOUN
fnp-3050	315	6	and	and	CCONJ
fnp-3050	315	7	their	their	PRON
fnp-3050	315	8	total	total	ADJ
fnp-3050	315	9	number	number	NOUN
fnp-3050	315	10	decreases	decrease	VERB
fnp-3050	315	11	with	with	ADP
fnp-3050	315	12	time	time	NOUN
fnp-3050	315	13	[	[	X
fnp-3050	315	14	61	61	NUM
fnp-3050	315	15	,	,	PUNCT
fnp-3050	315	16	208	208	NUM
fnp-3050	315	17	]	]	PUNCT
fnp-3050	315	18	.	.	PUNCT
fnp-3050	316	1	their	their	PRON
fnp-3050	316	2	loss	loss	NOUN
fnp-3050	316	3	has	have	AUX
fnp-3050	316	4	been	be	AUX
fnp-3050	316	5	demonstrated	demonstrate	VERB
fnp-3050	316	6	ultrastructurally	ultrastructurally	ADV
fnp-3050	316	7	and	and	CCONJ
fnp-3050	316	8	immunohistochemically	immunohistochemically	ADV
fnp-3050	317	1	[	[	X
fnp-3050	317	2	209	209	NUM
fnp-3050	317	3	]	]	PUNCT
fnp-3050	317	4	.	.	PUNCT
fnp-3050	318	1	in	in	ADP
fnp-3050	318	2	late	late	ADJ
fnp-3050	318	3	stages	stage	NOUN
fnp-3050	318	4	of	of	ADP
fnp-3050	318	5	ad	ad	NOUN
fnp-3050	318	6	synapse	synapse	NOUN
fnp-3050	318	7	loss	loss	NOUN
fnp-3050	318	8	ranges	range	VERB
fnp-3050	318	9	from	from	ADP
fnp-3050	318	10	10	10	NUM
fnp-3050	318	11	to	to	PART
fnp-3050	318	12	60	60	NUM
fnp-3050	318	13	%	%	NOUN
fnp-3050	318	14	,	,	PUNCT
fnp-3050	318	15	most	most	ADV
fnp-3050	318	16	severely	severely	ADV
fnp-3050	318	17	in	in	ADP
fnp-3050	318	18	the	the	DET
fnp-3050	318	19	frontal	frontal	ADJ
fnp-3050	318	20	and	and	CCONJ
fnp-3050	318	21	mesiotemporal	mesiotemporal	ADJ
fnp-3050	318	22	regions	region	NOUN
fnp-3050	318	23	.	.	PUNCT
fnp-3050	319	1	synapse	synapse	NOUN
fnp-3050	319	2	loss	loss	NOUN
fnp-3050	319	3	by	by	ADP
fnp-3050	319	4	activated	activate	VERB
fnp-3050	319	5	astrocytes	astrocyte	NOUN
fnp-3050	319	6	producing	produce	VERB
fnp-3050	319	7	different	different	ADJ
fnp-3050	319	8	secretomes	secretome	NOUN
fnp-3050	319	9	reduce	reduce	VERB
fnp-3050	319	10	protein	protein	NOUN
fnp-3050	319	11	synthesis	synthesis	NOUN
fnp-3050	319	12	for	for	ADP
fnp-3050	319	13	synapse	synapse	NOUN
fnp-3050	319	14	formation	formation	NOUN
fnp-3050	319	15	,	,	PUNCT
fnp-3050	319	16	resulting	result	VERB
fnp-3050	319	17	in	in	ADP
fnp-3050	319	18	synaptic	synaptic	ADJ
fnp-3050	319	19	loss	loss	NOUN
fnp-3050	319	20	found	find	VERB
fnp-3050	319	21	in	in	ADP
fnp-3050	319	22	ad	ad	NOUN
fnp-3050	319	23	[	[	X
fnp-3050	319	24	210	210	NUM
fnp-3050	319	25	]	]	PUNCT
fnp-3050	319	26	.	.	PUNCT
fnp-3050	320	1	there	there	PRON
fnp-3050	320	2	is	be	VERB
fnp-3050	320	3	a	a	DET
fnp-3050	320	4	close	close	ADJ
fnp-3050	320	5	relationship	relationship	NOUN
fnp-3050	320	6	between	between	ADP
fnp-3050	320	7	aβ	aβ	NOUN
fnp-3050	320	8	accumulation	accumulation	NOUN
fnp-3050	320	9	and	and	CCONJ
fnp-3050	320	10	synaptic	synaptic	ADJ
fnp-3050	320	11	loss	loss	NOUN
fnp-3050	320	12	that	that	PRON
fnp-3050	320	13	may	may	AUX
fnp-3050	320	14	provide	provide	VERB
fnp-3050	320	15	direction	direction	NOUN
fnp-3050	320	16	for	for	ADP
fnp-3050	320	17	the	the	DET
fnp-3050	320	18	development	development	NOUN
fnp-3050	320	19	of	of	ADP
fnp-3050	320	20	potential	potential	ADJ
fnp-3050	320	21	disease	disease	NOUN
fnp-3050	320	22	-	-	PUNCT
fnp-3050	320	23	modifying	modify	VERB
fnp-3050	320	24	treatments	treatment	NOUN
fnp-3050	320	25	of	of	ADP
fnp-3050	320	26	ad	ad	NOUN
fnp-3050	320	27	[	[	X
fnp-3050	320	28	211	211	NUM
fnp-3050	320	29	]	]	PUNCT
fnp-3050	320	30	.	.	PUNCT
fnp-3050	321	1	eoad	eoad	PROPN
fnp-3050	321	2	is	be	AUX
fnp-3050	321	3	associated	associate	VERB
fnp-3050	321	4	with	with	ADP
fnp-3050	321	5	a	a	DET
fnp-3050	321	6	higher	high	ADJ
fnp-3050	321	7	burden	burden	NOUN
fnp-3050	321	8	of	of	ADP
fnp-3050	321	9	adnc	adnc	NOUN
fnp-3050	321	10	and	and	CCONJ
fnp-3050	321	11	a	a	DET
fnp-3050	321	12	higher	high	ADJ
fnp-3050	321	13	rate	rate	NOUN
fnp-3050	321	14	of	of	ADP
fnp-3050	321	15	neocortical	neocortical	ADJ
fnp-3050	321	16	atrophy	atrophy	NOUN
fnp-3050	321	17	and	and	CCONJ
fnp-3050	321	18	synapse	synapse	VERB
fnp-3050	321	19	loss	loss	NOUN
fnp-3050	321	20	than	than	ADP
fnp-3050	321	21	the	the	DET
fnp-3050	321	22	much	much	ADV
fnp-3050	321	23	more	more	ADV
fnp-3050	321	24	common	common	ADJ
fnp-3050	321	25	and	and	CCONJ
fnp-3050	321	26	apparently	apparently	ADV
fnp-3050	321	27	sporadic	sporadic	ADJ
fnp-3050	321	28	load	load	NOUN
fnp-3050	321	29	[	[	X
fnp-3050	321	30	212	212	NUM
fnp-3050	321	31	]	]	PUNCT
fnp-3050	321	32	.	.	PUNCT
fnp-3050	322	1	however	however	ADV
fnp-3050	322	2	,	,	PUNCT
fnp-3050	322	3	synaptic	synaptic	ADJ
fnp-3050	322	4	loss	loss	NOUN
fnp-3050	322	5	is	be	AUX
fnp-3050	322	6	not	not	PART
fnp-3050	322	7	a	a	DET
fnp-3050	322	8	unique	unique	ADJ
fnp-3050	322	9	hallmark	hallmark	NOUN
fnp-3050	322	10	of	of	ADP
fnp-3050	322	11	ad	ad	NOUN
fnp-3050	322	12	and	and	CCONJ
fnp-3050	322	13	occurs	occur	VERB
fnp-3050	322	14	in	in	ADP
fnp-3050	322	15	many	many	ADJ
fnp-3050	322	16	other	other	ADJ
fnp-3050	322	17	brain	brain	NOUN
fnp-3050	322	18	diseases	disease	NOUN
fnp-3050	322	19	[	[	X
fnp-3050	322	20	213	213	NUM
fnp-3050	322	21	]	]	PUNCT
fnp-3050	322	22	.	.	PUNCT
fnp-3050	323	1	2.10	2.10	NUM
fnp-3050	323	2	.	.	PUNCT
fnp-3050	323	3	neuroinflammation	neuroinflammation	NOUN
fnp-3050	323	4	activated	activate	VERB
fnp-3050	323	5	microglia	microglia	NOUN
fnp-3050	323	6	operating	operating	NOUN
fnp-3050	323	7	as	as	SCONJ
fnp-3050	323	8	phagocytes	phagocyte	NOUN
fnp-3050	323	9	are	be	AUX
fnp-3050	323	10	frequently	frequently	ADV
fnp-3050	323	11	observed	observe	VERB
fnp-3050	323	12	around	around	ADP
fnp-3050	323	13	aβ	aβ	ADP
fnp-3050	323	14	plaques	plaque	NOUN
fnp-3050	323	15	driving	drive	VERB
fnp-3050	323	16	an	an	DET
fnp-3050	323	17	inflammatory	inflammatory	ADJ
fnp-3050	323	18	response	response	NOUN
fnp-3050	323	19	,	,	PUNCT
fnp-3050	323	20	which	which	PRON
fnp-3050	323	21	can	can	AUX
fnp-3050	323	22	be	be	AUX
fnp-3050	323	23	activated	activate	VERB
fnp-3050	323	24	by	by	ADP
fnp-3050	323	25	multiple	multiple	ADJ
fnp-3050	323	26	factors	factor	NOUN
fnp-3050	323	27	in	in	ADP
fnp-3050	323	28	the	the	DET
fnp-3050	323	29	local	local	ADJ
fnp-3050	323	30	environment	environment	NOUN
fnp-3050	324	1	[	[	X
fnp-3050	324	2	214	214	NUM
fnp-3050	324	3	]	]	PUNCT
fnp-3050	324	4	,	,	PUNCT
fnp-3050	324	5	in	in	ADP
fnp-3050	324	6	particular	particular	ADJ
fnp-3050	324	7	by	by	ADP
fnp-3050	324	8	the	the	DET
fnp-3050	324	9	presence	presence	NOUN
fnp-3050	324	10	of	of	ADP
fnp-3050	324	11	aβ	aβ	PRON
fnp-3050	324	12	in	in	ADP
fnp-3050	324	13	the	the	DET
fnp-3050	324	14	cortex	cortex	NOUN
fnp-3050	324	15	,	,	PUNCT
fnp-3050	324	16	indicating	indicate	VERB
fnp-3050	324	17	a	a	DET
fnp-3050	324	18	“	"	PUNCT
fnp-3050	324	19	toxic	toxic	ADJ
fnp-3050	324	20	”	"	PUNCT
fnp-3050	324	21	response	response	NOUN
fnp-3050	324	22	which	which	PRON
fnp-3050	324	23	corrupts	corrupt	VERB
fnp-3050	324	24	neurons	neuron	NOUN
fnp-3050	324	25	as	as	ADP
fnp-3050	324	26	collateral	collateral	ADJ
fnp-3050	324	27	damage	damage	NOUN
fnp-3050	324	28	(	(	PUNCT
fnp-3050	324	29	“	"	PUNCT
fnp-3050	324	30	bystander	bystander	NOUN
fnp-3050	324	31	effect	effect	NOUN
fnp-3050	324	32	”	"	PUNCT
fnp-3050	324	33	)	)	PUNCT
fnp-3050	325	1	[	[	X
fnp-3050	325	2	215	215	NUM
fnp-3050	325	3	]	]	PUNCT
fnp-3050	325	4	.	.	PUNCT
fnp-3050	326	1	tau	tau	NOUN
fnp-3050	326	2	-	-	PUNCT
fnp-3050	326	3	positive	positive	ADJ
fnp-3050	326	4	nps	nps	PROPN
fnp-3050	326	5	being	be	AUX
fnp-3050	326	6	early	early	ADV
fnp-3050	326	7	in	in	ADP
fnp-3050	326	8	ad	ad	NOUN
fnp-3050	326	9	,	,	PUNCT
fnp-3050	326	10	however	however	ADV
fnp-3050	326	11	,	,	PUNCT
fnp-3050	326	12	major	major	ADJ
fnp-3050	326	13	tau	tau	PROPN
fnp-3050	326	14	deposition	deposition	NOUN
fnp-3050	326	15	follows	follow	VERB
fnp-3050	326	16	the	the	DET
fnp-3050	326	17	accumulation	accumulation	NOUN
fnp-3050	326	18	of	of	ADP
fnp-3050	326	19	aβ	aβ	NOUN
fnp-3050	326	20	and	and	CCONJ
fnp-3050	326	21	clustering	clustering	NOUN
fnp-3050	326	22	of	of	ADP
fnp-3050	326	23	activated	activated	ADJ
fnp-3050	326	24	microglia	microglia	NOUN
fnp-3050	326	25	.	.	PUNCT
fnp-3050	327	1	an	an	DET
fnp-3050	327	2	increase	increase	NOUN
fnp-3050	327	3	in	in	ADP
fnp-3050	327	4	membrane	membrane	NOUN
fnp-3050	327	5	attack	attack	NOUN
fnp-3050	327	6	complex	complex	ADJ
fnp-3050	327	7	formation	formation	NOUN
fnp-3050	327	8	leads	lead	VERB
fnp-3050	327	9	to	to	ADP
fnp-3050	327	10	increased	increase	VERB
fnp-3050	327	11	tau	tau	PROPN
fnp-3050	327	12	pathology	pathology	NOUN
fnp-3050	327	13	and	and	CCONJ
fnp-3050	327	14	neoronal	neoronal	ADJ
fnp-3050	327	15	loss	loss	NOUN
fnp-3050	327	16	[	[	X
fnp-3050	327	17	216	216	NUM
fnp-3050	327	18	]	]	PUNCT
fnp-3050	327	19	.	.	PUNCT
fnp-3050	328	1	on	on	ADP
fnp-3050	328	2	the	the	DET
fnp-3050	328	3	other	other	ADJ
fnp-3050	328	4	hand	hand	NOUN
fnp-3050	328	5	,	,	PUNCT
fnp-3050	328	6	microglia	microglia	NOUN
fnp-3050	328	7	may	may	AUX
fnp-3050	328	8	contribute	contribute	VERB
fnp-3050	328	9	to	to	ADP
fnp-3050	328	10	elimination	elimination	NOUN
fnp-3050	328	11	of	of	ADP
fnp-3050	328	12	tau	tau	PROPN
fnp-3050	328	13	deposits	deposit	NOUN
fnp-3050	328	14	by	by	ADP
fnp-3050	328	15	phagocytosis	phagocytosis	NOUN
fnp-3050	328	16	[	[	X
fnp-3050	328	17	217	217	NUM
fnp-3050	328	18	,	,	PUNCT
fnp-3050	328	19	218	218	NUM
fnp-3050	328	20	]	]	PUNCT
fnp-3050	328	21	.	.	PUNCT
fnp-3050	329	1	different	different	ADJ
fnp-3050	329	2	states	state	NOUN
fnp-3050	329	3	of	of	ADP
fnp-3050	329	4	microglia	microglia	ADJ
fnp-3050	329	5	activation	activation	NOUN
fnp-3050	329	6	,	,	PUNCT
fnp-3050	329	7	corresponding	correspond	VERB
fnp-3050	329	8	to	to	ADP
fnp-3050	329	9	regional	regional	ADJ
fnp-3050	329	10	activation	activation	NOUN
fnp-3050	329	11	of	of	ADP
fnp-3050	329	12	aβ	aβ	PRON
fnp-3050	329	13	and	and	CCONJ
fnp-3050	329	14	tau	tau	PROPN
fnp-3050	329	15	,	,	PUNCT
fnp-3050	329	16	are	be	AUX
fnp-3050	329	17	present	present	ADJ
fnp-3050	329	18	simultaneously	simultaneously	ADV
fnp-3050	329	19	in	in	ADP
fnp-3050	329	20	the	the	DET
fnp-3050	329	21	same	same	ADJ
fnp-3050	329	22	brain	brain	NOUN
fnp-3050	329	23	.	.	PUNCT
fnp-3050	330	1	the	the	DET
fnp-3050	330	2	clustering	clustering	NOUN
fnp-3050	330	3	of	of	ADP
fnp-3050	330	4	activated	activate	VERB
fnp-3050	330	5	microglia	microglia	NOUN
fnp-3050	330	6	is	be	AUX
fnp-3050	330	7	greatest	great	ADJ
fnp-3050	330	8	in	in	ADP
fnp-3050	330	9	the	the	DET
fnp-3050	330	10	primary	primary	ADJ
fnp-3050	330	11	motor	motor	NOUN
fnp-3050	330	12	cortex	cortex	NOUN
fnp-3050	330	13	,	,	PUNCT
fnp-3050	330	14	a	a	DET
fnp-3050	330	15	region	region	NOUN
fnp-3050	330	16	relatively	relatively	ADV
fnp-3050	330	17	spared	spare	VERB
fnp-3050	330	18	compared	compare	VERB
fnp-3050	330	19	to	to	ADP
fnp-3050	330	20	the	the	DET
fnp-3050	330	21	severely	severely	ADV
fnp-3050	330	22	affected	affect	VERB
fnp-3050	330	23	inferior	inferior	ADJ
fnp-3050	330	24	temporal	temporal	ADJ
fnp-3050	330	25	cortex	cortex	NOUN
fnp-3050	330	26	in	in	ADP
fnp-3050	330	27	ad	ad	NOUN
fnp-3050	330	28	.	.	PUNCT
fnp-3050	331	1	this	this	PRON
fnp-3050	331	2	suggests	suggest	VERB
fnp-3050	331	3	that	that	SCONJ
fnp-3050	331	4	microglial	microglial	ADJ
fnp-3050	331	5	activation	activation	NOUN
fnp-3050	331	6	is	be	AUX
fnp-3050	331	7	not	not	PART
fnp-3050	331	8	prominent	prominent	ADJ
fnp-3050	331	9	in	in	ADP
fnp-3050	331	10	the	the	DET
fnp-3050	331	11	early	early	ADJ
fnp-3050	331	12	phase	phase	NOUN
fnp-3050	331	13	of	of	ADP
fnp-3050	331	14	ad	ad	NOUN
fnp-3050	331	15	pathophysiology	pathophysiology	NOUN
fnp-3050	332	1	[	[	X
fnp-3050	332	2	66	66	NUM
fnp-3050	332	3	]	]	PUNCT
fnp-3050	332	4	.	.	PUNCT
fnp-3050	333	1	recent	recent	ADJ
fnp-3050	333	2	studies	study	NOUN
fnp-3050	333	3	in	in	ADP
fnp-3050	333	4	hp	hp	PROPN
fnp-3050	333	5	-	-	ADJ
fnp-3050	333	6	tau	tau	NOUN
fnp-3050	333	7	mice	mouse	NOUN
fnp-3050	333	8	demonstrated	demonstrate	VERB
fnp-3050	333	9	that	that	SCONJ
fnp-3050	333	10	microglia	microglia	NOUN
fnp-3050	333	11	are	be	AUX
fnp-3050	333	12	not	not	PART
fnp-3050	333	13	the	the	DET
fnp-3050	333	14	agitators	agitator	NOUN
fnp-3050	333	15	of	of	ADP
fnp-3050	333	16	tau	tau	PROPN
fnp-3050	333	17	aggregation	aggregation	NOUN
fnp-3050	333	18	,	,	PUNCT
fnp-3050	333	19	but	but	CCONJ
fnp-3050	333	20	different	different	ADJ
fnp-3050	333	21	results	result	NOUN
fnp-3050	333	22	about	about	ADP
fnp-3050	333	23	the	the	DET
fnp-3050	333	24	involvement	involvement	NOUN
fnp-3050	333	25	of	of	ADP
fnp-3050	333	26	microglia	microglia	NOUN
fnp-3050	333	27	in	in	ADP
fnp-3050	333	28	tau	tau	PROPN
fnp-3050	333	29	aggregation	aggregation	NOUN
fnp-3050	333	30	and	and	CCONJ
fnp-3050	333	31	clearance	clearance	NOUN
fnp-3050	333	32	were	be	AUX
fnp-3050	333	33	presented	present	VERB
fnp-3050	333	34	[	[	X
fnp-3050	333	35	219	219	NUM
fnp-3050	333	36	,	,	PUNCT
fnp-3050	333	37	220	220	NUM
fnp-3050	333	38	]	]	PUNCT
fnp-3050	333	39	.	.	PUNCT
fnp-3050	334	1	thus	thus	ADV
fnp-3050	334	2	,	,	PUNCT
fnp-3050	334	3	the	the	DET
fnp-3050	334	4	functional	functional	ADJ
fnp-3050	334	5	role	role	NOUN
fnp-3050	334	6	of	of	ADP
fnp-3050	334	7	microglial	microglial	ADJ
fnp-3050	334	8	activation	activation	NOUN
fnp-3050	334	9	with	with	ADP
fnp-3050	334	10	hp	hp	PROPN
fnp-3050	334	11	-	-	ADJ
fnp-3050	334	12	tau	tau	NOUN
fnp-3050	334	13	oligomers	oligomer	NOUN
fnp-3050	334	14	still	still	ADV
fnp-3050	334	15	remains	remain	VERB
fnp-3050	334	16	elusive	elusive	ADJ
fnp-3050	334	17	.	.	PUNCT
fnp-3050	335	1	gene	gene	NOUN
fnp-3050	335	2	-	-	PUNCT
fnp-3050	335	3	profiling	profile	VERB
fnp-3050	335	4	technologies	technology	NOUN
fnp-3050	335	5	applied	apply	VERB
fnp-3050	335	6	to	to	ADP
fnp-3050	335	7	isolated	isolated	ADJ
fnp-3050	335	8	microglia	microglia	NOUN
fnp-3050	335	9	have	have	AUX
fnp-3050	335	10	challenged	challenge	VERB
fnp-3050	335	11	the	the	DET
fnp-3050	335	12	hypothesis	hypothesis	NOUN
fnp-3050	335	13	that	that	SCONJ
fnp-3050	335	14	there	there	PRON
fnp-3050	335	15	is	be	VERB
fnp-3050	335	16	one	one	NUM
fnp-3050	335	17	acute	acute	NOUN
fnp-3050	335	18	-	-	PUNCT
fnp-3050	335	19	type	type	NOUN
fnp-3050	335	20	(	(	PUNCT
fnp-3050	335	21	microglial	microglial	ADJ
fnp-3050	335	22	drivers	driver	NOUN
fnp-3050	335	23	)	)	PUNCT
fnp-3050	335	24	of	of	ADP
fnp-3050	335	25	inflammation	inflammation	NOUN
fnp-3050	335	26	in	in	ADP
fnp-3050	335	27	the	the	DET
fnp-3050	335	28	human	human	ADJ
fnp-3050	335	29	brain	brain	NOUN
fnp-3050	335	30	causing	cause	VERB
fnp-3050	335	31	accelerated	accelerate	VERB
fnp-3050	335	32	proinflammatory	proinflammatory	ADJ
fnp-3050	335	33	damage	damage	NOUN
fnp-3050	335	34	in	in	ADP
fnp-3050	335	35	ad	ad	NOUN
fnp-3050	335	36	.	.	PUNCT
fnp-3050	336	1	these	these	DET
fnp-3050	336	2	studies	study	NOUN
fnp-3050	336	3	have	have	AUX
fnp-3050	336	4	shown	show	VERB
fnp-3050	336	5	that	that	SCONJ
fnp-3050	336	6	many	many	ADJ
fnp-3050	336	7	of	of	ADP
fnp-3050	336	8	the	the	DET
fnp-3050	336	9	microglia	microglia	ADJ
fnp-3050	336	10	genes	gene	NOUN
fnp-3050	336	11	expressed	express	VERB
fnp-3050	336	12	in	in	ADP
fnp-3050	336	13	increased	increase	VERB
fnp-3050	336	14	levels	level	NOUN
fnp-3050	336	15	reflect	reflect	VERB
fnp-3050	336	16	a	a	DET
fnp-3050	336	17	response	response	NOUN
fnp-3050	336	18	to	to	PART
fnp-3050	336	19	restore	restore	VERB
fnp-3050	336	20	homeostasis	homeostasis	NOUN
fnp-3050	336	21	and	and	CCONJ
fnp-3050	336	22	limit	limit	VERB
fnp-3050	336	23	inflammatory	inflammatory	ADJ
fnp-3050	336	24	damage	damage	NOUN
fnp-3050	336	25	[	[	X
fnp-3050	336	26	221	221	NUM
fnp-3050	336	27	]	]	PUNCT
fnp-3050	336	28	.	.	PUNCT
fnp-3050	337	1	on	on	ADP
fnp-3050	337	2	the	the	DET
fnp-3050	337	3	other	other	ADJ
fnp-3050	337	4	hand	hand	NOUN
fnp-3050	337	5	,	,	PUNCT
fnp-3050	337	6	there	there	PRON
fnp-3050	337	7	is	be	VERB
fnp-3050	337	8	an	an	DET
fnp-3050	337	9	early	early	ADJ
fnp-3050	337	10	microglia	microglia	ADJ
fnp-3050	337	11	reaction	reaction	NOUN
fnp-3050	337	12	to	to	ADP
fnp-3050	337	13	ad	ad	NOUN
fnp-3050	337	14	pathology	pathology	NOUN
fnp-3050	337	15	,	,	PUNCT
fnp-3050	337	16	but	but	CCONJ
fnp-3050	337	17	a	a	DET
fnp-3050	337	18	loss	loss	NOUN
fnp-3050	337	19	of	of	ADP
fnp-3050	337	20	healthy	healthy	ADJ
fnp-3050	337	21	microglia	microglia	NOUN
fnp-3050	337	22	is	be	AUX
fnp-3050	337	23	the	the	DET
fnp-3050	337	24	prominent	prominent	ADJ
fnp-3050	337	25	feature	feature	NOUN
fnp-3050	337	26	in	in	ADP
fnp-3050	337	27	severely	severely	ADV
fnp-3050	337	28	affected	affect	VERB
fnp-3050	337	29	regions	region	NOUN
fnp-3050	337	30	of	of	ADP
fnp-3050	337	31	the	the	DET
fnp-3050	337	32	ad	ad	NOUN
fnp-3050	337	33	brain	brain	NOUN
fnp-3050	338	1	[	[	X
fnp-3050	338	2	222	222	NUM
fnp-3050	338	3	]	]	PUNCT
fnp-3050	338	4	.	.	PUNCT
fnp-3050	339	1	in	in	ADP
fnp-3050	339	2	addition	addition	NOUN
fnp-3050	339	3	,	,	PUNCT
fnp-3050	339	4	there	there	PRON
fnp-3050	339	5	is	be	VERB
fnp-3050	339	6	a	a	DET
fnp-3050	339	7	non	non	ADJ
fnp-3050	339	8	-	-	ADJ
fnp-3050	339	9	disease	disease	ADJ
fnp-3050	339	10	-	-	PUNCT
fnp-3050	339	11	specific	specific	ADJ
fnp-3050	339	12	response	response	NOUN
fnp-3050	339	13	of	of	ADP
fnp-3050	339	14	microglia	microglia	NOUN
fnp-3050	339	15	to	to	ADP
fnp-3050	339	16	neuronal	neuronal	ADJ
fnp-3050	339	17	damage	damage	NOUN
fnp-3050	339	18	,	,	PUNCT
fnp-3050	339	19	with	with	ADP
fnp-3050	339	20	upregulation	upregulation	NOUN
fnp-3050	339	21	of	of	ADP
fnp-3050	339	22	phagocytotic	phagocytotic	ADJ
fnp-3050	339	23	activity	activity	NOUN
fnp-3050	339	24	to	to	PART
fnp-3050	339	25	remove	remove	VERB
fnp-3050	339	26	damaged	damaged	ADJ
fnp-3050	339	27	neurons	neuron	NOUN
fnp-3050	339	28	and	and	CCONJ
fnp-3050	339	29	synapses	synapsis	NOUN
fnp-3050	339	30	by	by	ADP
fnp-3050	339	31	cd68	cd68	PROPN
fnp-3050	339	32	immunoreactivity	immunoreactivity	NOUN
fnp-3050	339	33	of	of	ADP
fnp-3050	339	34	lysosomes	lysosome	NOUN
fnp-3050	339	35	[	[	X
fnp-3050	339	36	73	73	NUM
fnp-3050	339	37	]	]	PUNCT
fnp-3050	339	38	.	.	PUNCT
fnp-3050	340	1	their	their	PRON
fnp-3050	340	2	numbers	number	NOUN
fnp-3050	340	3	increase	increase	VERB
fnp-3050	340	4	on	on	ADP
fnp-3050	340	5	promotion	promotion	NOUN
fnp-3050	340	6	to	to	ADP
fnp-3050	340	7	neuronal	neuronal	ADJ
fnp-3050	340	8	damage	damage	NOUN
fnp-3050	340	9	associated	associate	VERB
fnp-3050	340	10	with	with	ADP
fnp-3050	340	11	nfts	nft	NOUN
fnp-3050	340	12	[	[	X
fnp-3050	340	13	62	62	NUM
fnp-3050	340	14	]	]	PUNCT
fnp-3050	340	15	,	,	PUNCT
fnp-3050	340	16	which	which	PRON
fnp-3050	340	17	is	be	AUX
fnp-3050	340	18	due	due	ADJ
fnp-3050	340	19	to	to	ADP
fnp-3050	340	20	enhanced	enhance	VERB
fnp-3050	340	21	production	production	NOUN
fnp-3050	340	22	of	of	ADP
fnp-3050	340	23	inflammatory	inflammatory	ADJ
fnp-3050	340	24	cytokines	cytokine	NOUN
fnp-3050	340	25	,	,	PUNCT
fnp-3050	340	26	such	such	ADJ
fnp-3050	340	27	as	as	ADP
fnp-3050	340	28	il-21	il-21	PRON
fnp-3050	340	29	and	and	CCONJ
fnp-3050	340	30	increase	increase	VERB
fnp-3050	340	31	in	in	ADP
fnp-3050	340	32	t	t	PROPN
fnp-3050	340	33	follicular	follicular	ADJ
fnp-3050	340	34	helper	helper	NOUN
fnp-3050	340	35	cells	cell	NOUN
fnp-3050	340	36	.	.	PUNCT
fnp-3050	341	1	the	the	DET
fnp-3050	341	2	strong	strong	ADJ
fnp-3050	341	3	immune	immune	ADJ
fnp-3050	341	4	response	response	NOUN
fnp-3050	341	5	is	be	AUX
fnp-3050	341	6	insufficient	insufficient	ADJ
fnp-3050	341	7	at	at	ADP
fnp-3050	341	8	clearing	clear	VERB
fnp-3050	341	9	up	up	ADP
fnp-3050	341	10	aβ	aβ	ADP
fnp-3050	342	1	and	and	CCONJ
fnp-3050	342	2	instead	instead	ADV
fnp-3050	342	3	exacerbates	exacerbate	VERB
fnp-3050	342	4	inflammation	inflammation	NOUN
fnp-3050	342	5	[	[	X
fnp-3050	342	6	223	223	NUM
fnp-3050	342	7	]	]	PUNCT
fnp-3050	342	8	.	.	PUNCT
fnp-3050	343	1	reactive	reactive	ADJ
fnp-3050	343	2	astrocytes	astrocyte	NOUN
fnp-3050	343	3	that	that	PRON
fnp-3050	343	4	may	may	AUX
fnp-3050	343	5	react	react	VERB
fnp-3050	343	6	to	to	ADP
fnp-3050	343	7	cytokines	cytokine	NOUN
fnp-3050	343	8	and	and	CCONJ
fnp-3050	343	9	other	other	ADJ
fnp-3050	343	10	agents	agent	NOUN
fnp-3050	343	11	produced	produce	VERB
fnp-3050	343	12	by	by	ADP
fnp-3050	343	13	pro	pro	ADJ
fnp-3050	343	14	-	-	ADJ
fnp-3050	343	15	inflammatory	inflammatory	ADJ
fnp-3050	343	16	microglia	microglia	NOUN
fnp-3050	343	17	,	,	PUNCT
fnp-3050	343	18	are	be	AUX
fnp-3050	343	19	observed	observe	VERB
fnp-3050	343	20	around	around	ADP
fnp-3050	343	21	aps	ap	NOUN
fnp-3050	343	22	,	,	PUNCT
fnp-3050	343	23	though	though	SCONJ
fnp-3050	343	24	less	less	ADV
fnp-3050	343	25	frequently	frequently	ADV
fnp-3050	343	26	compared	compare	VERB
fnp-3050	343	27	to	to	ADP
fnp-3050	343	28	microglia	microglia	PROPN
fnp-3050	343	29	.	.	PUNCT
fnp-3050	344	1	reactive	reactive	ADJ
fnp-3050	344	2	astroglia	astroglia	PROPN
fnp-3050	344	3	burden	burden	NOUN
fnp-3050	344	4	occurs	occur	VERB
fnp-3050	344	5	later	later	ADV
fnp-3050	344	6	in	in	ADP
fnp-3050	344	7	ad	ad	NOUN
fnp-3050	344	8	and	and	CCONJ
fnp-3050	344	9	correlates	correlate	VERB
fnp-3050	344	10	mainly	mainly	ADV
fnp-3050	344	11	with	with	ADP
fnp-3050	344	12	tau	tau	PROPN
fnp-3050	344	13	pathology	pathology	NOUN
fnp-3050	345	1	[	[	X
fnp-3050	345	2	31	31	NUM
fnp-3050	345	3	]	]	PUNCT
fnp-3050	345	4	.	.	PUNCT
fnp-3050	346	1	2.11	2.11	NUM
fnp-3050	346	2	.	.	PUNCT
fnp-3050	346	3	pathology	pathology	NOUN
fnp-3050	346	4	of	of	ADP
fnp-3050	346	5	preclinical	preclinical	ADJ
fnp-3050	346	6	ad	ad	NOUN
fnp-3050	346	7	amyloid	amyloid	NOUN
fnp-3050	346	8	and	and	CCONJ
fnp-3050	346	9	neuritic	neuritic	ADJ
fnp-3050	346	10	plaques	plaque	NOUN
fnp-3050	346	11	and	and	CCONJ
fnp-3050	346	12	nfts	nft	NOUN
fnp-3050	346	13	occurring	occur	VERB
fnp-3050	346	14	in	in	ADP
fnp-3050	346	15	non	non	ADJ
fnp-3050	346	16	-	-	ADJ
fnp-3050	346	17	demented	demented	ADJ
fnp-3050	346	18	elderly	elderly	ADJ
fnp-3050	346	19	individuals	individual	NOUN
fnp-3050	346	20	,	,	PUNCT
fnp-3050	346	21	represent	represent	VERB
fnp-3050	346	22	asymptomatic	asymptomatic	ADJ
fnp-3050	346	23	or	or	CCONJ
fnp-3050	346	24	preclinical	preclinical	ADJ
fnp-3050	346	25	ad	ad	NOUN
fnp-3050	346	26	(	(	PUNCT
fnp-3050	346	27	pre	pre	NOUN
fnp-3050	346	28	-	-	NOUN
fnp-3050	346	29	ad	ad	NOUN
fnp-3050	346	30	)	)	PUNCT
fnp-3050	346	31	,	,	PUNCT
fnp-3050	346	32	while	while	SCONJ
fnp-3050	346	33	clinical	clinical	ADJ
fnp-3050	346	34	ad	ad	NOUN
fnp-3050	346	35	affects	affect	VERB
fnp-3050	346	36	subjects	subject	NOUN
fnp-3050	346	37	with	with	ADP
fnp-3050	346	38	late	late	ADJ
fnp-3050	346	39	stages	stage	NOUN
fnp-3050	346	40	of	of	ADP
fnp-3050	346	41	adnc	adnc	NOUN
fnp-3050	346	42	.	.	PUNCT
fnp-3050	347	1	both	both	DET
fnp-3050	347	2	ad	ad	NOUN
fnp-3050	347	3	and	and	CCONJ
fnp-3050	347	4	pre	pre	ADJ
fnp-3050	347	5	-	-	ADJ
fnp-3050	347	6	ad	ad	ADJ
fnp-3050	347	7	cases	case	NOUN
fnp-3050	347	8	often	often	ADV
fnp-3050	347	9	exhibit	exhibit	VERB
fnp-3050	347	10	caa	caa	NOUN
fnp-3050	347	11	,	,	PUNCT
fnp-3050	347	12	which	which	PRON
fnp-3050	347	13	is	be	AUX
fnp-3050	347	14	also	also	ADV
fnp-3050	347	15	observed	observe	VERB
fnp-3050	347	16	in	in	ADP
fnp-3050	347	17	non	non	ADJ
fnp-3050	347	18	-	-	ADJ
fnp-3050	347	19	ad	ad	ADJ
fnp-3050	347	20	cases	case	NOUN
fnp-3050	347	21	,	,	PUNCT
fnp-3050	347	22	i.e.	i.e.	X
fnp-3050	347	23	,	,	PUNCT
fnp-3050	347	24	those	those	PRON
fnp-3050	347	25	without	without	ADP
fnp-3050	347	26	adnc	adnc	ADJ
fnp-3050	347	27	.	.	PUNCT
fnp-3050	348	1	patients	patient	NOUN
fnp-3050	348	2	with	with	ADP
fnp-3050	348	3	mci	mci	PROPN
fnp-3050	348	4	do	do	AUX
fnp-3050	348	5	not	not	PART
fnp-3050	348	6	always	always	ADV
fnp-3050	348	7	have	have	VERB
fnp-3050	348	8	adnc	adnc	ADJ
fnp-3050	348	9	even	even	ADV
fnp-3050	348	10	though	though	SCONJ
fnp-3050	348	11	they	they	PRON
fnp-3050	348	12	have	have	VERB
fnp-3050	348	13	a	a	DET
fnp-3050	348	14	risk	risk	NOUN
fnp-3050	348	15	of	of	ADP
fnp-3050	348	16	developing	develop	VERB
fnp-3050	348	17	dementia	dementia	NOUN
fnp-3050	348	18	in	in	ADP
fnp-3050	348	19	10	10	NUM
fnp-3050	348	20	-	-	SYM
fnp-3050	348	21	12	12	NUM
fnp-3050	348	22	%	%	NOUN
fnp-3050	348	23	and	and	CCONJ
fnp-3050	348	24	sometimes	sometimes	ADV
fnp-3050	348	25	do	do	AUX
fnp-3050	348	26	not	not	PART
fnp-3050	348	27	have	have	VERB
fnp-3050	348	28	any	any	DET
fnp-3050	348	29	discernable	discernable	ADJ
fnp-3050	348	30	pathology	pathology	NOUN
fnp-3050	348	31	[	[	X
fnp-3050	348	32	224	224	NUM
fnp-3050	348	33	,	,	PUNCT
fnp-3050	348	34	225	225	NUM
fnp-3050	348	35	]	]	PUNCT
fnp-3050	348	36	.	.	PUNCT
fnp-3050	349	1	the	the	DET
fnp-3050	349	2	presence	presence	NOUN
fnp-3050	349	3	of	of	ADP
fnp-3050	349	4	nfts	nft	NOUN
fnp-3050	349	5	and	and	CCONJ
fnp-3050	349	6	caa	caa	NOUN
fnp-3050	349	7	in	in	ADP
fnp-3050	349	8	cases	case	NOUN
fnp-3050	349	9	without	without	ADP
fnp-3050	349	10	aps	ap	NOUN
fnp-3050	349	11	,	,	PUNCT
fnp-3050	349	12	classified	classify	VERB
fnp-3050	349	13	as	as	ADP
fnp-3050	349	14	non	non	NOUN
fnp-3050	349	15	-	-	NOUN
fnp-3050	349	16	ad	ad	NOUN
fnp-3050	349	17	,	,	PUNCT
fnp-3050	349	18	suggests	suggest	VERB
fnp-3050	349	19	that	that	SCONJ
fnp-3050	349	20	they	they	PRON
fnp-3050	349	21	may	may	AUX
fnp-3050	349	22	precede	precede	VERB
fnp-3050	349	23	ap	ap	PROPN
fnp-3050	349	24	pathology	pathology	NOUN
fnp-3050	349	25	or	or	CCONJ
fnp-3050	349	26	may	may	AUX
fnp-3050	349	27	present	present	VERB
fnp-3050	349	28	a	a	DET
fnp-3050	349	29	pre	pre	ADJ
fnp-3050	349	30	-	-	ADJ
fnp-3050	349	31	amyloid	amyloid	ADJ
fnp-3050	349	32	plaque	plaque	NOUN
fnp-3050	349	33	stage	stage	NOUN
fnp-3050	349	34	not	not	PART
fnp-3050	349	35	yet	yet	ADV
fnp-3050	349	36	included	include	VERB
fnp-3050	349	37	in	in	ADP
fnp-3050	349	38	the	the	DET
fnp-3050	349	39	current	current	ADJ
fnp-3050	349	40	criteria	criterion	NOUN
fnp-3050	349	41	for	for	ADP
fnp-3050	349	42	the	the	DET
fnp-3050	349	43	neuropathological	neuropathological	ADJ
fnp-3050	349	44	diagnosis	diagnosis	NOUN
fnp-3050	349	45	of	of	ADP
fnp-3050	349	46	ad	ad	NOUN
fnp-3050	349	47	[	[	X
fnp-3050	349	48	226	226	NUM
fnp-3050	349	49	]	]	PUNCT
fnp-3050	349	50	.	.	PUNCT
fnp-3050	350	1	increased	increase	VERB
fnp-3050	350	2	soluble	soluble	ADJ
fnp-3050	350	3	/	/	SYM
fnp-3050	350	4	dispersible	dispersible	ADJ
fnp-3050	350	5	aβ	aβ	NOUN
fnp-3050	350	6	in	in	ADP
fnp-3050	350	7	pre	pre	NOUN
fnp-3050	350	8	-	-	NOUN
fnp-3050	350	9	ad	ad	NOUN
fnp-3050	350	10	compared	compare	VERB
fnp-3050	350	11	to	to	ADP
fnp-3050	350	12	fully	fully	ADV
fnp-3050	350	13	developed	develop	VERB
fnp-3050	350	14	suggests	suggest	VERB
fnp-3050	350	15	that	that	SCONJ
fnp-3050	350	16	,	,	PUNCT
fnp-3050	350	17	in	in	ADP
fnp-3050	350	18	addition	addition	NOUN
fnp-3050	350	19	to	to	ADP
fnp-3050	350	20	more	more	ADV
fnp-3050	350	21	severe	severe	ADJ
fnp-3050	350	22	and	and	CCONJ
fnp-3050	350	23	widespread	widespread	ADJ
fnp-3050	350	24	adnc	adnc	ADJ
fnp-3050	350	25	,	,	PUNCT
fnp-3050	350	26	soluble	soluble	ADJ
fnp-3050	351	1	aβ	aβ	NOUN
fnp-3050	351	2	aggregates	aggregate	NOUN
fnp-3050	351	3	play	play	VERB
fnp-3050	351	4	a	a	DET
fnp-3050	351	5	role	role	NOUN
fnp-3050	351	6	in	in	ADP
fnp-3050	351	7	the	the	DET
fnp-3050	351	8	conversion	conversion	NOUN
fnp-3050	351	9	of	of	ADP
fnp-3050	351	10	pre	pre	NOUN
fnp-3050	351	11	-	-	NOUN
fnp-3050	351	12	ad	ad	NOUN
fnp-3050	351	13	to	to	ADP
fnp-3050	351	14	clinical	clinical	ADJ
fnp-3050	351	15	ad	ad	NOUN
fnp-3050	351	16	[	[	X
fnp-3050	351	17	31	31	NUM
fnp-3050	351	18	]	]	PUNCT
fnp-3050	351	19	.	.	PUNCT
fnp-3050	352	1	cognitively	cognitively	ADV
fnp-3050	352	2	impaired	impair	VERB
fnp-3050	352	3	individuals	individual	NOUN
fnp-3050	352	4	presenting	present	VERB
fnp-3050	352	5	with	with	ADP
fnp-3050	352	6	an	an	DET
fnp-3050	352	7	early	early	ADJ
fnp-3050	352	8	onset	onset	NOUN
fnp-3050	352	9	ad	ad	NOUN
fnp-3050	352	10	phenotype	phenotype	NOUN
fnp-3050	352	11	showed	show	VERB
fnp-3050	352	12	higher	high	ADJ
fnp-3050	352	13	rates	rate	NOUN
fnp-3050	352	14	of	of	ADP
fnp-3050	352	15	tau	tau	PROPN
fnp-3050	352	16	pet	pet	ADJ
fnp-3050	352	17	accumulation	accumulation	NOUN
fnp-3050	352	18	,	,	PUNCT
fnp-3050	352	19	while	while	SCONJ
fnp-3050	352	20	among	among	ADP
fnp-3050	352	21	cognitively	cognitively	ADV
fnp-3050	352	22	unimpaired	unimpaire	VERB
fnp-3050	352	23	individuals	individual	NOUN
fnp-3050	352	24	higher	high	ADJ
fnp-3050	352	25	rates	rate	NOUN
fnp-3050	352	26	of	of	ADP
fnp-3050	352	27	tau	tau	PROPN
fnp-3050	352	28	accumulation	accumulation	NOUN
fnp-3050	352	29	were	be	AUX
fnp-3050	352	30	associated	associate	VERB
fnp-3050	352	31	with	with	ADP
fnp-3050	352	32	faster	fast	ADJ
fnp-3050	352	33	rates	rate	NOUN
fnp-3050	352	34	of	of	ADP
fnp-3050	352	35	memory	memory	NOUN
fnp-3050	352	36	decline	decline	NOUN
fnp-3050	352	37	[	[	X
fnp-3050	352	38	227	227	NUM
fnp-3050	352	39	]	]	PUNCT
fnp-3050	352	40	.	.	PUNCT
fnp-3050	353	1	2.12	2.12	NUM
fnp-3050	353	2	.	.	PUNCT
fnp-3050	353	3	neuropathological	neuropathological	ADJ
fnp-3050	353	4	diagnosis	diagnosis	NOUN
fnp-3050	353	5	of	of	ADP
fnp-3050	353	6	alzheimer	alzheimer	PROPN
fnp-3050	353	7	’s	’s	PART
fnp-3050	353	8	disease	disease	NOUN
fnp-3050	353	9	histopathological	histopathological	ADJ
fnp-3050	353	10	examination	examination	NOUN
fnp-3050	353	11	of	of	ADP
fnp-3050	353	12	the	the	DET
fnp-3050	353	13	brain	brain	NOUN
fnp-3050	353	14	has	have	VERB
fnp-3050	353	15	to	to	PART
fnp-3050	353	16	establish	establish	VERB
fnp-3050	353	17	that	that	DET
fnp-3050	353	18	adnc	adnc	ADJ
fnp-3050	353	19	are	be	AUX
fnp-3050	353	20	present	present	ADJ
fnp-3050	353	21	in	in	ADP
fnp-3050	353	22	sufficient	sufficient	ADJ
fnp-3050	353	23	densities	density	NOUN
fnp-3050	353	24	and	and	CCONJ
fnp-3050	353	25	extensions	extension	NOUN
fnp-3050	353	26	to	to	PART
fnp-3050	353	27	distinguish	distinguish	VERB
fnp-3050	353	28	ad	ad	NOUN
fnp-3050	353	29	from	from	ADP
fnp-3050	353	30	other	other	ADJ
fnp-3050	353	31	age	age	NOUN
fnp-3050	353	32	-	-	PUNCT
fnp-3050	353	33	related	relate	VERB
fnp-3050	353	34	disorders	disorder	NOUN
fnp-3050	353	35	[	[	X
fnp-3050	353	36	61	61	NUM
fnp-3050	353	37	]	]	PUNCT
fnp-3050	353	38	.	.	PUNCT
fnp-3050	354	1	because	because	SCONJ
fnp-3050	354	2	the	the	DET
fnp-3050	354	3	disease	disease	NOUN
fnp-3050	354	4	affects	affect	VERB
fnp-3050	354	5	the	the	DET
fnp-3050	354	6	whole	whole	ADJ
fnp-3050	354	7	brain	brain	NOUN
fnp-3050	354	8	,	,	PUNCT
fnp-3050	354	9	it	it	PRON
fnp-3050	354	10	is	be	AUX
fnp-3050	354	11	not	not	PART
fnp-3050	354	12	sufficient	sufficient	ADJ
fnp-3050	354	13	to	to	PART
fnp-3050	354	14	make	make	VERB
fnp-3050	354	15	the	the	DET
fnp-3050	354	16	diagnosis	diagnosis	NOUN
fnp-3050	354	17	of	of	ADP
fnp-3050	354	18	ad	ad	NOUN
fnp-3050	354	19	just	just	ADV
fnp-3050	354	20	on	on	ADP
fnp-3050	354	21	one	one	NUM
fnp-3050	354	22	or	or	CCONJ
fnp-3050	354	23	two	two	NUM
fnp-3050	354	24	brain	brain	NOUN
fnp-3050	354	25	blocks	block	NOUN
fnp-3050	354	26	;	;	PUNCT
fnp-3050	354	27	instead	instead	ADV
fnp-3050	354	28	,	,	PUNCT
fnp-3050	354	29	multiple	multiple	ADJ
fnp-3050	354	30	brain	brain	NOUN
fnp-3050	354	31	areas	area	NOUN
fnp-3050	354	32	have	have	VERB
fnp-3050	354	33	to	to	PART
fnp-3050	354	34	be	be	AUX
fnp-3050	354	35	examined	examine	VERB
fnp-3050	354	36	and	and	CCONJ
fnp-3050	354	37	a	a	DET
fnp-3050	354	38	staging	staging	NOUN
fnp-3050	354	39	protocol	protocol	NOUN
fnp-3050	354	40	has	have	VERB
fnp-3050	354	41	to	to	PART
fnp-3050	354	42	be	be	AUX
fnp-3050	354	43	established	establish	VERB
fnp-3050	354	44	.	.	PUNCT
fnp-3050	355	1	the	the	DET
fnp-3050	355	2	current	current	ADJ
fnp-3050	355	3	algorithms	algorithm	NOUN
fnp-3050	355	4	for	for	ADP
fnp-3050	355	5	the	the	DET
fnp-3050	355	6	pathological	pathological	ADJ
fnp-3050	355	7	diagnosis	diagnosis	NOUN
fnp-3050	355	8	of	of	ADP
fnp-3050	355	9	ad	ad	NOUN
fnp-3050	355	10	are	be	AUX
fnp-3050	355	11	based	base	VERB
fnp-3050	355	12	on	on	ADP
fnp-3050	355	13	semiquantiative	semiquantiative	ADJ
fnp-3050	355	14	assessment	assessment	NOUN
fnp-3050	355	15	of	of	ADP
fnp-3050	355	16	aps	ap	NOUN
fnp-3050	355	17	and	and	CCONJ
fnp-3050	355	18	nfts	nft	NOUN
fnp-3050	355	19	providing	provide	VERB
fnp-3050	355	20	reasonable	reasonable	ADJ
fnp-3050	355	21	interrater	interrater	NOUN
fnp-3050	355	22	agreement	agreement	NOUN
fnp-3050	355	23	when	when	SCONJ
fnp-3050	355	24	using	use	VERB
fnp-3050	355	25	standardized	standardized	ADJ
fnp-3050	355	26	criteria	criterion	NOUN
fnp-3050	355	27	[	[	X
fnp-3050	355	28	228	228	NUM
fnp-3050	355	29	]	]	PUNCT
fnp-3050	355	30	.	.	PUNCT
fnp-3050	356	1	current	current	ADJ
fnp-3050	356	2	guidelines	guideline	NOUN
fnp-3050	356	3	include	include	VERB
fnp-3050	356	4	(	(	PUNCT
fnp-3050	356	5	a	a	PRON
fnp-3050	356	6	)	)	PUNCT
fnp-3050	356	7	cut	cut	NOUN
fnp-3050	356	8	-	-	PUNCT
fnp-3050	356	9	off	off	ADP
fnp-3050	356	10	quantitative	quantitative	ADJ
fnp-3050	356	11	values	value	NOUN
fnp-3050	356	12	for	for	ADP
fnp-3050	356	13	aps	ap	NOUN
fnp-3050	356	14	and	and	CCONJ
fnp-3050	356	15	tangles	tangle	NOUN
fnp-3050	356	16	[	[	X
fnp-3050	356	17	17	17	NUM
fnp-3050	356	18	,	,	PUNCT
fnp-3050	356	19	229	229	NUM
fnp-3050	356	20	]	]	PUNCT
fnp-3050	356	21	;	;	PUNCT
fnp-3050	356	22	(	(	PUNCT
fnp-3050	356	23	b	b	X
fnp-3050	356	24	)	)	PUNCT
fnp-3050	356	25	the	the	DET
fnp-3050	356	26	semiquantitative	semiquantitative	ADJ
fnp-3050	356	27	assessment	assessment	NOUN
fnp-3050	356	28	and	and	CCONJ
fnp-3050	356	29	age	age	NOUN
fnp-3050	356	30	-	-	PUNCT
fnp-3050	356	31	adjustment	adjustment	NOUN
fnp-3050	356	32	of	of	ADP
fnp-3050	356	33	nps	nps	PROPN
fnp-3050	356	34	in	in	ADP
fnp-3050	356	35	the	the	DET
fnp-3050	356	36	consortium	consortium	NOUN
fnp-3050	356	37	to	to	PART
fnp-3050	356	38	establish	establish	VERB
fnp-3050	356	39	a	a	DET
fnp-3050	356	40	registry	registry	NOUN
fnp-3050	356	41	for	for	ADP
fnp-3050	356	42	alzheimer	alzheimer	PROPN
fnp-3050	356	43	's	's	PART
fnp-3050	356	44	disease	disease	NOUN
fnp-3050	356	45	(	(	PUNCT
fnp-3050	356	46	cerad	cerad	NOUN
fnp-3050	356	47	)	)	PUNCT
fnp-3050	356	48	protocol	protocol	NOUN
fnp-3050	357	1	[	[	X
fnp-3050	357	2	230	230	NUM
fnp-3050	357	3	]	]	PUNCT
fnp-3050	357	4	;	;	PUNCT
fnp-3050	357	5	(	(	PUNCT
fnp-3050	357	6	c	c	X
fnp-3050	357	7	)	)	PUNCT
fnp-3050	357	8	topographic	topographic	ADJ
fnp-3050	357	9	staging	staging	NOUN
fnp-3050	357	10	of	of	ADP
fnp-3050	357	11	neuritic	neuritic	ADJ
fnp-3050	357	12	/	/	SYM
fnp-3050	357	13	tau	tau	PROPN
fnp-3050	357	14	pathology	pathology	NOUN
fnp-3050	358	1	[	[	X
fnp-3050	358	2	18	18	NUM
fnp-3050	358	3	]	]	PUNCT
fnp-3050	358	4	,	,	PUNCT
fnp-3050	358	5	re	re	VERB
fnp-3050	358	6	-	-	VERB
fnp-3050	358	7	evaluated	evaluate	VERB
fnp-3050	358	8	by	by	ADP
fnp-3050	358	9	immunohistochemistry	immunohistochemistry	NOUN
fnp-3050	358	10	[	[	X
fnp-3050	358	11	231	231	NUM
fnp-3050	358	12	]	]	PUNCT
fnp-3050	358	13	;	;	PUNCT
fnp-3050	358	14	and	and	CCONJ
fnp-3050	358	15	(	(	PUNCT
fnp-3050	358	16	d	d	X
fnp-3050	358	17	)	)	PUNCT
fnp-3050	358	18	the	the	DET
fnp-3050	358	19	progress	progress	NOUN
fnp-3050	358	20	and	and	CCONJ
fnp-3050	358	21	distribution	distribution	NOUN
fnp-3050	358	22	of	of	ADP
fnp-3050	358	23	aβ	aβ	DET
fnp-3050	358	24	phases	phase	NOUN
fnp-3050	358	25	[	[	X
fnp-3050	358	26	79	79	NUM
fnp-3050	358	27	]	]	PUNCT
fnp-3050	358	28	.	.	PUNCT
fnp-3050	359	1	in	in	ADP
fnp-3050	359	2	order	order	NOUN
fnp-3050	359	3	to	to	PART
fnp-3050	359	4	develop	develop	VERB
fnp-3050	359	5	a	a	DET
fnp-3050	359	6	system	system	NOUN
fnp-3050	359	7	that	that	PRON
fnp-3050	359	8	combines	combine	VERB
fnp-3050	359	9	all	all	DET
fnp-3050	359	10	the	the	DET
fnp-3050	359	11	above	above	ADJ
fnp-3050	359	12	pathological	pathological	ADJ
fnp-3050	359	13	features	feature	NOUN
fnp-3050	359	14	,	,	PUNCT
fnp-3050	359	15	the	the	DET
fnp-3050	359	16	nia	nia	PROPN
fnp-3050	359	17	/	/	SYM
fnp-3050	359	18	aa	aa	PROPN
fnp-3050	359	19	established	establish	VERB
fnp-3050	359	20	a	a	DET
fnp-3050	359	21	composite	composite	ADJ
fnp-3050	359	22	score	score	NOUN
fnp-3050	359	23	comprising	comprise	VERB
fnp-3050	359	24	the	the	DET
fnp-3050	359	25	extent	extent	NOUN
fnp-3050	359	26	of	of	ADP
fnp-3050	359	27	involvement	involvement	NOUN
fnp-3050	359	28	/	/	SYM
fnp-3050	359	29	spread	spread	NOUN
fnp-3050	359	30	of	of	ADP
fnp-3050	359	31	cerebral	cerebral	ADJ
fnp-3050	359	32	aβ	aβ	NOUN
fnp-3050	359	33	based	base	VERB
fnp-3050	359	34	on	on	ADP
fnp-3050	359	35	the	the	DET
fnp-3050	359	36	progression	progression	NOUN
fnp-3050	359	37	model	model	NOUN
fnp-3050	359	38	by	by	ADP
fnp-3050	359	39	the	the	DET
fnp-3050	359	40	thal	thal	PROPN
fnp-3050	359	41	phases	phase	NOUN
fnp-3050	359	42	:	:	PUNCT
fnp-3050	359	43	(	(	PUNCT
fnp-3050	359	44	a	a	X
fnp-3050	359	45	)	)	PUNCT
fnp-3050	359	46	,	,	PUNCT
fnp-3050	359	47	that	that	PRON
fnp-3050	359	48	of	of	ADP
fnp-3050	359	49	nfts	nft	NOUN
fnp-3050	359	50	based	base	VERB
fnp-3050	359	51	on	on	ADP
fnp-3050	359	52	the	the	DET
fnp-3050	359	53	progression	progression	NOUN
fnp-3050	359	54	model	model	NOUN
fnp-3050	359	55	of	of	ADP
fnp-3050	359	56	braak	braak	NOUN
fnp-3050	359	57	,	,	PUNCT
fnp-3050	359	58	(	(	PUNCT
fnp-3050	359	59	b	b	NOUN
fnp-3050	359	60	)	)	PUNCT
fnp-3050	359	61	,	,	PUNCT
fnp-3050	359	62	and	and	CCONJ
fnp-3050	359	63	the	the	DET
fnp-3050	359	64	cerad	cerad	PROPN
fnp-3050	359	65	score	score	NOUN
fnp-3050	359	66	,	,	PUNCT
fnp-3050	359	67	which	which	PRON
fnp-3050	359	68	describes	describe	VERB
fnp-3050	359	69	the	the	DET
fnp-3050	359	70	density	density	NOUN
fnp-3050	359	71	of	of	ADP
fnp-3050	359	72	neuritic	neuritic	ADJ
fnp-3050	359	73	amyloid	amyloid	NOUN
fnp-3050	359	74	plaques	plaque	NOUN
fnp-3050	359	75	based	base	VERB
fnp-3050	359	76	on	on	ADP
fnp-3050	359	77	certain	certain	ADJ
fnp-3050	359	78	key	key	ADJ
fnp-3050	359	79	locations	location	NOUN
fnp-3050	359	80	in	in	ADP
fnp-3050	359	81	the	the	DET
fnp-3050	359	82	neocortex	neocortex	NOUN
fnp-3050	359	83	,	,	PUNCT
fnp-3050	359	84	(	(	PUNCT
fnp-3050	359	85	c	c	X
fnp-3050	359	86	)	)	PUNCT
fnp-3050	359	87	(	(	PUNCT
fnp-3050	359	88	table	table	NOUN
fnp-3050	359	89	1	1	NUM
fnp-3050	359	90	)	)	PUNCT
fnp-3050	359	91	.	.	PUNCT
fnp-3050	360	1	from	from	ADP
fnp-3050	360	2	this	this	DET
fnp-3050	360	3	combination	combination	NOUN
fnp-3050	360	4	,	,	PUNCT
fnp-3050	360	5	it	it	PRON
fnp-3050	360	6	gave	give	VERB
fnp-3050	360	7	a	a	DET
fnp-3050	360	8	likelihood	likelihood	NOUN
fnp-3050	360	9	for	for	ADP
fnp-3050	360	10	the	the	DET
fnp-3050	360	11	degree	degree	NOUN
fnp-3050	360	12	of	of	ADP
fnp-3050	360	13	ad	ad	NOUN
fnp-3050	360	14	neuropathological	neuropathological	ADJ
fnp-3050	360	15	changes	change	NOUN
fnp-3050	360	16	in	in	ADP
fnp-3050	360	17	an	an	DET
fnp-3050	360	18	individual	individual	ADJ
fnp-3050	360	19	case	case	NOUN
fnp-3050	360	20	.	.	PUNCT
fnp-3050	361	1	sufficient	sufficient	ADJ
fnp-3050	361	2	agreement	agreement	NOUN
fnp-3050	361	3	in	in	ADP
fnp-3050	361	4	ad	ad	NOUN
fnp-3050	361	5	diagnosis	diagnosis	NOUN
fnp-3050	361	6	could	could	AUX
fnp-3050	361	7	be	be	AUX
fnp-3050	361	8	reached	reach	VERB
fnp-3050	361	9	only	only	ADV
fnp-3050	361	10	when	when	SCONJ
fnp-3050	361	11	the	the	DET
fnp-3050	361	12	lesions	lesion	NOUN
fnp-3050	361	13	are	be	AUX
fnp-3050	361	14	considerable	considerable	ADJ
fnp-3050	361	15	(	(	PUNCT
fnp-3050	361	16	braak	braak	PROPN
fnp-3050	361	17	nft	nft	PROPN
fnp-3050	361	18	stage	stage	PROPN
fnp-3050	361	19	v	v	PROPN
fnp-3050	361	20	and	and	CCONJ
fnp-3050	361	21	vi	vi	NUM
fnp-3050	361	22	)	)	PUNCT
fnp-3050	361	23	with	with	ADP
fnp-3050	361	24	91	91	NUM
fnp-3050	361	25	%	%	NOUN
fnp-3050	361	26	agreement	agreement	NOUN
fnp-3050	361	27	,	,	PUNCT
fnp-3050	361	28	while	while	SCONJ
fnp-3050	361	29	for	for	ADP
fnp-3050	361	30	mild	mild	ADJ
fnp-3050	361	31	lesions	lesion	NOUN
fnp-3050	361	32	it	it	PRON
fnp-3050	361	33	was	be	AUX
fnp-3050	361	34	poorer	poor	ADJ
fnp-3050	361	35	(	(	PUNCT
fnp-3050	361	36	for	for	ADP
fnp-3050	361	37	braak	braak	ADJ
fnp-3050	361	38	stage	stage	NOUN
fnp-3050	361	39	i	i	PRON
fnp-3050	361	40	and	and	CCONJ
fnp-3050	361	41	ii	ii	PROPN
fnp-3050	361	42	,	,	PUNCT
fnp-3050	361	43	agreement	agreement	NOUN
fnp-3050	361	44	was	be	AUX
fnp-3050	361	45	only	only	ADV
fnp-3050	361	46	around	around	ADP
fnp-3050	361	47	50	50	NUM
fnp-3050	361	48	%	%	NOUN
fnp-3050	361	49	)	)	PUNCT
fnp-3050	362	1	[	[	X
fnp-3050	362	2	228	228	NUM
fnp-3050	362	3	,	,	PUNCT
fnp-3050	362	4	232	232	NUM
fnp-3050	362	5	,	,	PUNCT
fnp-3050	362	6	233	233	NUM
fnp-3050	362	7	]	]	PUNCT
fnp-3050	362	8	.	.	PUNCT
fnp-3050	363	1	combined	combined	ADJ
fnp-3050	363	2	braak	braak	NOUN
fnp-3050	363	3	and	and	CCONJ
fnp-3050	363	4	cerad	cerad	VERB
fnp-3050	363	5	scores	score	NOUN
fnp-3050	363	6	in	in	ADP
fnp-3050	363	7	the	the	DET
fnp-3050	363	8	nia	nia	PROPN
fnp-3050	363	9	-	-	PUNCT
fnp-3050	363	10	ri	ri	PROPN
fnp-3050	363	11	(	(	PUNCT
fnp-3050	363	12	national	national	PROPN
fnp-3050	363	13	institute	institute	NOUN
fnp-3050	363	14	on	on	ADP
fnp-3050	363	15	aging	aging	NOUN
fnp-3050	363	16	and	and	CCONJ
fnp-3050	363	17	reagan	reagan	PROPN
fnp-3050	363	18	institute	institute	PROPN
fnp-3050	363	19	)	)	PUNCT
fnp-3050	363	20	criteria	criterion	NOUN
fnp-3050	363	21	that	that	PRON
fnp-3050	363	22	apply	apply	VERB
fnp-3050	363	23	only	only	ADV
fnp-3050	363	24	to	to	ADP
fnp-3050	363	25	demented	demented	ADJ
fnp-3050	363	26	persons	person	NOUN
fnp-3050	363	27	,	,	PUNCT
fnp-3050	363	28	relate	relate	VERB
fnp-3050	363	29	dementia	dementia	NOUN
fnp-3050	363	30	to	to	PART
fnp-3050	363	31	adnc	adnc	VERB
fnp-3050	363	32	with	with	ADP
fnp-3050	363	33	high	high	ADJ
fnp-3050	363	34	,	,	PUNCT
fnp-3050	363	35	intermediate	intermediate	ADJ
fnp-3050	363	36	and	and	CCONJ
fnp-3050	363	37	low	low	ADJ
fnp-3050	363	38	likelihood	likelihood	NOUN
fnp-3050	364	1	[	[	X
fnp-3050	364	2	234	234	NUM
fnp-3050	364	3	]	]	PUNCT
fnp-3050	364	4	.	.	PUNCT
fnp-3050	365	1	they	they	PRON
fnp-3050	365	2	have	have	AUX
fnp-3050	365	3	been	be	AUX
fnp-3050	365	4	widely	widely	ADV
fnp-3050	365	5	used	use	VERB
fnp-3050	365	6	in	in	ADP
fnp-3050	365	7	anglo	anglo	ADJ
fnp-3050	365	8	-	-	PUNCT
fnp-3050	365	9	american	american	ADJ
fnp-3050	365	10	neuropathology	neuropathology	NOUN
fnp-3050	365	11	and	and	CCONJ
fnp-3050	365	12	are	be	AUX
fnp-3050	365	13	now	now	ADV
fnp-3050	365	14	replaced	replace	VERB
fnp-3050	365	15	by	by	ADP
fnp-3050	365	16	the	the	DET
fnp-3050	365	17	nia	nia	PROPN
fnp-3050	365	18	/	/	SYM
fnp-3050	365	19	aa	aa	PROPN
fnp-3050	365	20	guidelines	guideline	NOUN
fnp-3050	365	21	.	.	PUNCT
fnp-3050	366	1	although	although	SCONJ
fnp-3050	366	2	the	the	DET
fnp-3050	366	3	sensitivity	sensitivity	NOUN
fnp-3050	366	4	and	and	CCONJ
fnp-3050	366	5	specificity	specificity	NOUN
fnp-3050	366	6	of	of	ADP
fnp-3050	366	7	the	the	DET
fnp-3050	366	8	nia	nia	PROPN
fnp-3050	366	9	-	-	PUNCT
fnp-3050	366	10	ri	ri	PROPN
fnp-3050	366	11	criteria	criterion	NOUN
fnp-3050	366	12	has	have	AUX
fnp-3050	366	13	been	be	AUX
fnp-3050	366	14	proposed	propose	VERB
fnp-3050	366	15	to	to	PART
fnp-3050	366	16	be	be	AUX
fnp-3050	366	17	around	around	ADV
fnp-3050	366	18	90	90	NUM
fnp-3050	366	19	%	%	NOUN
fnp-3050	366	20	,	,	PUNCT
fnp-3050	366	21	only	only	ADV
fnp-3050	366	22	30	30	NUM
fnp-3050	366	23	to	to	PART
fnp-3050	366	24	57	57	NUM
fnp-3050	366	25	%	%	NOUN
fnp-3050	366	26	of	of	ADP
fnp-3050	366	27	the	the	DET
fnp-3050	366	28	brains	brain	NOUN
fnp-3050	366	29	of	of	ADP
fnp-3050	366	30	patients	patient	NOUN
fnp-3050	366	31	with	with	ADP
fnp-3050	366	32	the	the	DET
fnp-3050	366	33	clinical	clinical	ADJ
fnp-3050	366	34	diagnosis	diagnosis	NOUN
fnp-3050	366	35	of	of	ADP
fnp-3050	366	36	probable	probable	ADJ
fnp-3050	366	37	ad	ad	NOUN
fnp-3050	366	38	showed	show	VERB
fnp-3050	366	39	“	"	PUNCT
fnp-3050	366	40	pure	pure	ADJ
fnp-3050	366	41	”	"	PUNCT
fnp-3050	366	42	adnc	adnc	ADJ
fnp-3050	366	43	,	,	PUNCT
fnp-3050	366	44	thus	thus	ADV
fnp-3050	366	45	reducing	reduce	VERB
fnp-3050	366	46	their	their	PRON
fnp-3050	366	47	predictive	predictive	ADJ
fnp-3050	366	48	value	value	NOUN
fnp-3050	366	49	to	to	ADP
fnp-3050	366	50	38	38	NUM
fnp-3050	366	51	%	%	NOUN
fnp-3050	366	52	[	[	X
fnp-3050	366	53	235	235	NUM
fnp-3050	366	54	]	]	PUNCT
fnp-3050	366	55	.	.	PUNCT
fnp-3050	367	1	an	an	DET
fnp-3050	367	2	evaluation	evaluation	NOUN
fnp-3050	367	3	of	of	ADP
fnp-3050	367	4	the	the	DET
fnp-3050	367	5	nia	nia	PROPN
fnp-3050	367	6	-	-	PUNCT
fnp-3050	367	7	ri	ri	PROPN
fnp-3050	367	8	criteria	criterion	NOUN
fnp-3050	367	9	identified	identify	VERB
fnp-3050	367	10	between	between	ADP
fnp-3050	367	11	54	54	NUM
fnp-3050	367	12	and	and	CCONJ
fnp-3050	367	13	97	97	NUM
fnp-3050	367	14	%	%	NOUN
fnp-3050	367	15	of	of	ADP
fnp-3050	367	16	ad	ad	NOUN
fnp-3050	367	17	cases	case	NOUN
fnp-3050	367	18	with	with	ADP
fnp-3050	367	19	high	high	ADJ
fnp-3050	367	20	braak	braak	NOUN
fnp-3050	367	21	or	or	CCONJ
fnp-3050	367	22	cerad	cerad	VERB
fnp-3050	367	23	stages	stage	NOUN
fnp-3050	367	24	,	,	PUNCT
fnp-3050	367	25	and	and	CCONJ
fnp-3050	367	26	eliminated	eliminate	VERB
fnp-3050	367	27	between	between	ADP
fnp-3050	367	28	60	60	NUM
fnp-3050	367	29	and	and	CCONJ
fnp-3050	367	30	100	100	NUM
fnp-3050	367	31	%	%	NOUN
fnp-3050	367	32	of	of	ADP
fnp-3050	367	33	non	non	NOUN
fnp-3050	367	34	-	-	NOUN
fnp-3050	367	35	ad	ad	NOUN
fnp-3050	367	36	with	with	ADP
fnp-3050	367	37	low	low	ADJ
fnp-3050	367	38	braak	braak	NOUN
fnp-3050	367	39	or	or	CCONJ
fnp-3050	367	40	cerad	cerad	VERB
fnp-3050	367	41	stages	stage	NOUN
fnp-3050	367	42	[	[	X
fnp-3050	367	43	232	232	NUM
fnp-3050	367	44	,	,	PUNCT
fnp-3050	367	45	233	233	NUM
fnp-3050	367	46	]	]	PUNCT
fnp-3050	367	47	.	.	PUNCT
fnp-3050	368	1	another	another	DET
fnp-3050	368	2	autopsy	autopsy	ADJ
fnp-3050	368	3	study	study	NOUN
fnp-3050	368	4	reported	report	VERB
fnp-3050	368	5	diagnostic	diagnostic	ADJ
fnp-3050	368	6	sensitivity	sensitivity	NOUN
fnp-3050	368	7	ranging	range	VERB
fnp-3050	368	8	from	from	ADP
fnp-3050	368	9	70.9	70.9	NUM
fnp-3050	368	10	to	to	PART
fnp-3050	368	11	87.3	87.3	NUM
fnp-3050	368	12	%	%	NOUN
fnp-3050	368	13	and	and	CCONJ
fnp-3050	368	14	specificity	specificity	NOUN
fnp-3050	368	15	from	from	ADP
fnp-3050	368	16	44.3	44.3	NUM
fnp-3050	368	17	to	to	PART
fnp-3050	368	18	70.8	70.8	NUM
fnp-3050	368	19	%	%	NOUN
fnp-3050	368	20	[	[	X
fnp-3050	368	21	236	236	NUM
fnp-3050	368	22	]	]	PUNCT
fnp-3050	368	23	.	.	PUNCT
fnp-3050	369	1	the	the	DET
fnp-3050	369	2	recent	recent	ADJ
fnp-3050	369	3	updated	update	VERB
fnp-3050	369	4	nia	nia	PROPN
fnp-3050	369	5	/	/	SYM
fnp-3050	369	6	aa	aa	PROPN
fnp-3050	369	7	guidelines	guideline	NOUN
fnp-3050	369	8	for	for	ADP
fnp-3050	369	9	the	the	DET
fnp-3050	369	10	neuropathological	neuropathological	ADJ
fnp-3050	369	11	assessment	assessment	NOUN
fnp-3050	369	12	of	of	ADP
fnp-3050	369	13	ad	ad	NOUN
fnp-3050	369	14	consider	consider	VERB
fnp-3050	369	15	adnc	adnc	ADJ
fnp-3050	369	16	levels	level	NOUN
fnp-3050	369	17	regardless	regardless	ADV
fnp-3050	369	18	of	of	ADP
fnp-3050	369	19	the	the	DET
fnp-3050	369	20	clinical	clinical	ADJ
fnp-3050	369	21	history	history	NOUN
fnp-3050	369	22	of	of	ADP
fnp-3050	369	23	a	a	DET
fnp-3050	369	24	given	give	VERB
fnp-3050	369	25	individual	individual	NOUN
fnp-3050	369	26	[	[	X
fnp-3050	369	27	17	17	NUM
fnp-3050	369	28	]	]	PUNCT
fnp-3050	369	29	.	.	PUNCT
fnp-3050	370	1	they	they	PRON
fnp-3050	370	2	include	include	VERB
fnp-3050	370	3	(	(	PUNCT
fnp-3050	370	4	1	1	X
fnp-3050	370	5	)	)	PUNCT
fnp-3050	370	6	the	the	DET
fnp-3050	370	7	recognition	recognition	NOUN
fnp-3050	370	8	that	that	SCONJ
fnp-3050	370	9	adnc	adnc	PROPN
fnp-3050	370	10	may	may	AUX
fnp-3050	370	11	occur	occur	VERB
fnp-3050	370	12	in	in	ADP
fnp-3050	370	13	the	the	DET
fnp-3050	370	14	apparent	apparent	ADJ
fnp-3050	370	15	absence	absence	NOUN
fnp-3050	370	16	of	of	ADP
fnp-3050	370	17	cognitive	cognitive	ADJ
fnp-3050	370	18	impairment	impairment	NOUN
fnp-3050	370	19	;	;	PUNCT
fnp-3050	370	20	(	(	PUNCT
fnp-3050	370	21	2	2	X
fnp-3050	370	22	)	)	PUNCT
fnp-3050	370	23	the	the	DET
fnp-3050	370	24	use	use	NOUN
fnp-3050	370	25	of	of	ADP
fnp-3050	370	26	an	an	DET
fnp-3050	370	27	“	"	PUNCT
fnp-3050	370	28	abc	abc	PROPN
fnp-3050	370	29	”	"	PUNCT
fnp-3050	370	30	score	score	NOUN
fnp-3050	370	31	for	for	ADP
fnp-3050	370	32	adnc	adnc	NOUN
fnp-3050	370	33	that	that	PRON
fnp-3050	370	34	incorporates	incorporate	VERB
fnp-3050	370	35	histological	histological	ADJ
fnp-3050	370	36	assessment	assessment	NOUN
fnp-3050	370	37	of	of	ADP
fnp-3050	370	38	aβ	aβ	DET
fnp-3050	370	39	plaques	plaque	NOUN
fnp-3050	370	40	(	(	PUNCT
fnp-3050	370	41	a	a	X
fnp-3050	370	42	)	)	PUNCT
fnp-3050	370	43	,	,	PUNCT
fnp-3050	370	44	based	base	VERB
fnp-3050	370	45	on	on	ADP
fnp-3050	370	46	its	its	PRON
fnp-3050	370	47	phase	phase	NOUN
fnp-3050	370	48	assessment	assessment	NOUN
fnp-3050	370	49	[	[	X
fnp-3050	370	50	79	79	NUM
fnp-3050	370	51	]	]	PUNCT
fnp-3050	370	52	,	,	PUNCT
fnp-3050	370	53	staging	staging	NOUN
fnp-3050	370	54	of	of	ADP
fnp-3050	370	55	nfts	nft	NOUN
fnp-3050	370	56	,	,	PUNCT
fnp-3050	370	57	(	(	PUNCT
fnp-3050	370	58	b	b	NOUN
fnp-3050	370	59	)	)	PUNCT
fnp-3050	370	60	based	base	VERB
fnp-3050	370	61	on	on	ADP
fnp-3050	370	62	the	the	DET
fnp-3050	370	63	braak	braak	NOUN
fnp-3050	370	64	staging	staging	NOUN
fnp-3050	370	65	system	system	NOUN
fnp-3050	370	66	[	[	X
fnp-3050	370	67	231	231	NUM
fnp-3050	370	68	]	]	PUNCT
fnp-3050	370	69	,	,	PUNCT
fnp-3050	370	70	and	and	CCONJ
fnp-3050	370	71	scoring	scoring	NOUN
fnp-3050	370	72	of	of	ADP
fnp-3050	370	73	nps	nps	PROPN
fnp-3050	370	74	,	,	PUNCT
fnp-3050	370	75	based	base	VERB
fnp-3050	370	76	on	on	ADP
fnp-3050	370	77	their	their	PRON
fnp-3050	370	78	semiquantitative	semiquantitative	ADJ
fnp-3050	370	79	assessment	assessment	NOUN
fnp-3050	370	80	in	in	ADP
fnp-3050	370	81	at	at	ADV
fnp-3050	370	82	least	least	ADV
fnp-3050	370	83	three	three	NUM
fnp-3050	370	84	neocortical	neocortical	ADJ
fnp-3050	370	85	regions	region	NOUN
fnp-3050	370	86	,	,	PUNCT
fnp-3050	370	87	and	and	CCONJ
fnp-3050	370	88	(	(	PUNCT
fnp-3050	370	89	c	c	NOUN
fnp-3050	370	90	)	)	PUNCT
fnp-3050	370	91	,	,	PUNCT
fnp-3050	370	92	based	base	VERB
fnp-3050	370	93	on	on	ADP
fnp-3050	370	94	cerad	cerad	ADJ
fnp-3050	370	95	criteria	criterion	NOUN
fnp-3050	370	96	[	[	X
fnp-3050	370	97	230	230	NUM
fnp-3050	370	98	]	]	PUNCT
fnp-3050	370	99	.	.	PUNCT
fnp-3050	371	1	table	table	NOUN
fnp-3050	371	2	2	2	NUM
fnp-3050	371	3	shows	show	VERB
fnp-3050	371	4	how	how	SCONJ
fnp-3050	371	5	each	each	PRON
fnp-3050	371	6	of	of	ADP
fnp-3050	371	7	the	the	DET
fnp-3050	371	8	three	three	NUM
fnp-3050	371	9	scores	score	NOUN
fnp-3050	371	10	are	be	AUX
fnp-3050	371	11	transformed	transform	VERB
fnp-3050	371	12	to	to	PART
fnp-3050	371	13	state	state	VERB
fnp-3050	371	14	the	the	DET
fnp-3050	371	15	level	level	NOUN
fnp-3050	371	16	of	of	ADP
fnp-3050	371	17	adnc	adnc	NOUN
fnp-3050	371	18	on	on	ADP
fnp-3050	371	19	a	a	DET
fnp-3050	371	20	four	four	NUM
fnp-3050	371	21	tiered	tiere	VERB
fnp-3050	371	22	scale	scale	NOUN
fnp-3050	371	23	(	(	PUNCT
fnp-3050	371	24	non	non	ADJ
fnp-3050	371	25	,	,	PUNCT
fnp-3050	371	26	low	low	ADJ
fnp-3050	371	27	,	,	PUNCT
fnp-3050	371	28	intermediate	intermediate	ADJ
fnp-3050	371	29	,	,	PUNCT
fnp-3050	371	30	and	and	CCONJ
fnp-3050	371	31	high	high	ADJ
fnp-3050	371	32	)	)	PUNCT
fnp-3050	371	33	.	.	PUNCT
fnp-3050	372	1	the	the	DET
fnp-3050	372	2	entire	entire	ADJ
fnp-3050	372	3	process	process	NOUN
fnp-3050	372	4	of	of	ADP
fnp-3050	372	5	the	the	DET
fnp-3050	372	6	neuropathological	neuropathological	ADJ
fnp-3050	372	7	diagnosis	diagnosis	NOUN
fnp-3050	372	8	of	of	ADP
fnp-3050	372	9	ad	ad	NOUN
fnp-3050	372	10	can	can	AUX
fnp-3050	372	11	be	be	AUX
fnp-3050	372	12	followed	follow	VERB
fnp-3050	372	13	along	along	ADP
fnp-3050	372	14	the	the	DET
fnp-3050	372	15	pathways	pathway	NOUN
fnp-3050	372	16	shown	show	VERB
fnp-3050	372	17	in	in	ADP
fnp-3050	372	18	fig	fig	NOUN
fnp-3050	372	19	.	.	PUNCT
fnp-3050	373	1	8	8	NUM
fnp-3050	373	2	.	.	PUNCT
fnp-3050	373	3	(	(	PUNCT
fnp-3050	373	4	3	3	X
fnp-3050	373	5	)	)	PUNCT
fnp-3050	373	6	more	more	ADV
fnp-3050	373	7	detailed	detailed	ADJ
fnp-3050	373	8	approaches	approach	NOUN
fnp-3050	373	9	for	for	ADP
fnp-3050	373	10	assessing	assess	VERB
fnp-3050	373	11	co	co	ADJ
fnp-3050	373	12	-	-	ADJ
fnp-3050	373	13	morbid	morbid	ADJ
fnp-3050	373	14	conditions	condition	NOUN
fnp-3050	373	15	,	,	PUNCT
fnp-3050	373	16	such	such	ADJ
fnp-3050	373	17	as	as	ADP
fnp-3050	373	18	lewy	lewy	PROPN
fnp-3050	373	19	pathology	pathology	PROPN
fnp-3050	373	20	,	,	PUNCT
fnp-3050	373	21	vascular	vascular	ADJ
fnp-3050	373	22	brain	brain	NOUN
fnp-3050	373	23	injury	injury	NOUN
fnp-3050	373	24	,	,	PUNCT
fnp-3050	373	25	tdp-43	tdp-43	VERB
fnp-3050	373	26	immunoreactive	immunoreactive	ADJ
fnp-3050	373	27	lesions	lesion	NOUN
fnp-3050	373	28	,	,	PUNCT
fnp-3050	373	29	argyrophilic	argyrophilic	ADJ
fnp-3050	373	30	grain	grain	NOUN
fnp-3050	373	31	disease	disease	NOUN
fnp-3050	373	32	,	,	PUNCT
fnp-3050	373	33	and	and	CCONJ
fnp-3050	373	34	others	other	NOUN
fnp-3050	373	35	that	that	PRON
fnp-3050	373	36	can	can	AUX
fnp-3050	373	37	complicate	complicate	VERB
fnp-3050	373	38	the	the	DET
fnp-3050	373	39	pathological	pathological	ADJ
fnp-3050	373	40	diagnosis	diagnosis	NOUN
fnp-3050	373	41	and	and	CCONJ
fnp-3050	373	42	can	can	AUX
fnp-3050	373	43	sometimes	sometimes	ADV
fnp-3050	373	44	co	co	VERB
fnp-3050	373	45	-	-	VERB
fnp-3050	373	46	exist	exist	VERB
fnp-3050	373	47	with	with	ADP
fnp-3050	373	48	ad	ad	NOUN
fnp-3050	373	49	,	,	PUNCT
fnp-3050	373	50	are	be	AUX
fnp-3050	373	51	also	also	ADV
fnp-3050	373	52	considered	consider	VERB
fnp-3050	373	53	[	[	X
fnp-3050	373	54	17	17	NUM
fnp-3050	373	55	]	]	PUNCT
fnp-3050	373	56	.	.	PUNCT
fnp-3050	374	1	testing	testing	NOUN
fnp-3050	374	2	of	of	ADP
fnp-3050	374	3	the	the	DET
fnp-3050	374	4	revised	revise	VERB
fnp-3050	374	5	nia	nia	PROPN
fnp-3050	374	6	/	/	SYM
fnp-3050	374	7	aa	aa	PROPN
fnp-3050	374	8	guidelines	guideline	NOUN
fnp-3050	374	9	in	in	ADP
fnp-3050	374	10	390	390	NUM
fnp-3050	374	11	autopsy	autopsy	ADJ
fnp-3050	374	12	cases	case	NOUN
fnp-3050	374	13	distinguished	distinguish	VERB
fnp-3050	374	14	pure	pure	ADJ
fnp-3050	374	15	ad	ad	NOUN
fnp-3050	374	16	and	and	CCONJ
fnp-3050	374	17	non	non	ADJ
fnp-3050	374	18	-	-	ADJ
fnp-3050	374	19	ad	ad	ADJ
fnp-3050	374	20	dementia	dementia	NOUN
fnp-3050	374	21	from	from	ADP
fnp-3050	374	22	non	non	ADJ
fnp-3050	374	23	-	-	ADJ
fnp-3050	374	24	demented	demented	ADJ
fnp-3050	374	25	cases	case	NOUN
fnp-3050	374	26	with	with	ADP
fnp-3050	374	27	a	a	DET
fnp-3050	374	28	sensitivity	sensitivity	NOUN
fnp-3050	374	29	of	of	ADP
fnp-3050	374	30	91	91	NUM
fnp-3050	374	31	%	%	NOUN
fnp-3050	374	32	and	and	CCONJ
fnp-3050	374	33	a	a	DET
fnp-3050	374	34	specificity	specificity	NOUN
fnp-3050	374	35	of	of	ADP
fnp-3050	374	36	99	99	NUM
fnp-3050	374	37	%	%	NOUN
fnp-3050	374	38	.	.	PUNCT
fnp-3050	375	1	the	the	DET
fnp-3050	375	2	sensitivity	sensitivity	NOUN
fnp-3050	375	3	increased	increase	VERB
fnp-3050	375	4	after	after	ADP
fnp-3050	375	5	exclusion	exclusion	NOUN
fnp-3050	375	6	of	of	ADP
fnp-3050	375	7	non	non	ADJ
fnp-3050	375	8	-	-	ADJ
fnp-3050	375	9	ad	ad	ADJ
fnp-3050	375	10	dementia	dementia	NOUN
fnp-3050	375	11	cases	case	NOUN
fnp-3050	375	12	,	,	PUNCT
fnp-3050	375	13	indicating	indicate	VERB
fnp-3050	375	14	that	that	SCONJ
fnp-3050	375	15	the	the	DET
fnp-3050	375	16	revised	revise	VERB
fnp-3050	375	17	nia	nia	PROPN
fnp-3050	375	18	/	/	SYM
fnp-3050	375	19	aa	aa	PROPN
fnp-3050	375	20	criteria	criterion	NOUN
fnp-3050	375	21	appear	appear	VERB
fnp-3050	375	22	practicable	practicable	ADJ
fnp-3050	375	23	for	for	ADP
fnp-3050	375	24	distinguishing	distinguish	VERB
fnp-3050	375	25	pure	pure	ADJ
fnp-3050	375	26	ad	ad	NOUN
fnp-3050	375	27	from	from	ADP
fnp-3050	375	28	non	non	ADJ
fnp-3050	375	29	-	-	ADJ
fnp-3050	375	30	ad	ad	ADJ
fnp-3050	375	31	dementia	dementia	NOUN
fnp-3050	375	32	,	,	PUNCT
fnp-3050	375	33	preclinical	preclinical	ADJ
fnp-3050	375	34	ad	ad	NOUN
fnp-3050	375	35	,	,	PUNCT
fnp-3050	375	36	and	and	CCONJ
fnp-3050	375	37	controls	control	VERB
fnp-3050	375	38	[	[	X
fnp-3050	375	39	226	226	NUM
fnp-3050	375	40	]	]	PUNCT
fnp-3050	375	41	.	.	PUNCT
fnp-3050	376	1	the	the	DET
fnp-3050	376	2	revised	revise	VERB
fnp-3050	376	3	nia	nia	PROPN
fnp-3050	376	4	/	/	SYM
fnp-3050	376	5	aa	aa	PROPN
fnp-3050	376	6	guidelines	guideline	NOUN
fnp-3050	376	7	for	for	ADP
fnp-3050	376	8	the	the	DET
fnp-3050	376	9	severity	severity	NOUN
fnp-3050	376	10	score	score	NOUN
fnp-3050	376	11	for	for	ADP
fnp-3050	376	12	adnc	adnc	ADJ
fnp-3050	376	13	used	use	VERB
fnp-3050	376	14	in	in	ADP
fnp-3050	376	15	the	the	DET
fnp-3050	376	16	ad	ad	NOUN
fnp-3050	376	17	centers	center	NOUN
fnp-3050	376	18	program	program	NOUN
fnp-3050	376	19	achieved	achieve	VERB
fnp-3050	376	20	an	an	DET
fnp-3050	376	21	excellent	excellent	ADJ
fnp-3050	376	22	agreement	agreement	NOUN
fnp-3050	376	23	(	(	PUNCT
fnp-3050	376	24	κ=0.88	κ=0.88	NOUN
fnp-3050	376	25	,	,	PUNCT
fnp-3050	376	26	95	95	NUM
fnp-3050	376	27	%	%	NOUN
fnp-3050	376	28	ci	ci	NOUN
fnp-3050	376	29	0.77	0.77	NUM
fnp-3050	376	30	-	-	SYM
fnp-3050	376	31	0.95	0.95	NUM
fnp-3050	376	32	)	)	PUNCT
fnp-3050	376	33	,	,	PUNCT
fnp-3050	376	34	and	and	CCONJ
fnp-3050	376	35	good	good	ADJ
fnp-3050	376	36	-	-	PUNCT
fnp-3050	376	37	to	to	ADP
fnp-3050	376	38	-	-	PUNCT
fnp-3050	376	39	excellent	excellent	ADJ
fnp-3050	376	40	agreement	agreement	NOUN
fnp-3050	376	41	for	for	ADP
fnp-3050	376	42	the	the	DET
fnp-3050	376	43	three	three	NUM
fnp-3050	376	44	supporting	support	VERB
fnp-3050	376	45	scores	score	NOUN
fnp-3050	376	46	[	[	X
fnp-3050	376	47	237	237	NUM
fnp-3050	376	48	]	]	PUNCT
fnp-3050	376	49	.	.	PUNCT
fnp-3050	377	1	figure	figure	NOUN
fnp-3050	377	2	8	8	NUM
fnp-3050	377	3	.	.	PUNCT
fnp-3050	378	1	pathway	pathway	NOUN
fnp-3050	378	2	of	of	ADP
fnp-3050	378	3	the	the	DET
fnp-3050	378	4	combination	combination	NOUN
fnp-3050	378	5	of	of	ADP
fnp-3050	378	6	different	different	ADJ
fnp-3050	378	7	pathological	pathological	ADJ
fnp-3050	378	8	features	feature	NOUN
fnp-3050	378	9	that	that	PRON
fnp-3050	378	10	allows	allow	VERB
fnp-3050	378	11	a	a	DET
fnp-3050	378	12	classification	classification	NOUN
fnp-3050	378	13	of	of	ADP
fnp-3050	378	14	adnc	adnc	NOUN
fnp-3050	378	15	according	accord	VERB
fnp-3050	378	16	to	to	ADP
fnp-3050	378	17	the	the	DET
fnp-3050	378	18	nia	nia	PROPN
fnp-3050	378	19	-	-	PUNCT
fnp-3050	378	20	aa	aa	PROPN
fnp-3050	378	21	guidelines	guideline	NOUN
fnp-3050	378	22	.	.	PUNCT
fnp-3050	379	1	a	a	DET
fnp-3050	379	2	comparative	comparative	ADJ
fnp-3050	379	3	study	study	NOUN
fnp-3050	379	4	of	of	ADP
fnp-3050	379	5	clinical	clinical	ADJ
fnp-3050	379	6	and	and	CCONJ
fnp-3050	379	7	neuropathological	neuropathological	ADJ
fnp-3050	379	8	diagnoses	diagnosis	NOUN
fnp-3050	379	9	of	of	ADP
fnp-3050	379	10	ad	ad	NOUN
fnp-3050	379	11	in	in	ADP
fnp-3050	379	12	three	three	NUM
fnp-3050	379	13	epidemiological	epidemiological	ADJ
fnp-3050	379	14	samples	sample	NOUN
fnp-3050	379	15	reported	report	VERB
fnp-3050	379	16	a	a	DET
fnp-3050	379	17	sensitivity	sensitivity	NOUN
fnp-3050	379	18	for	for	ADP
fnp-3050	379	19	probable	probable	ADJ
fnp-3050	379	20	ad	ad	NOUN
fnp-3050	379	21	of	of	ADP
fnp-3050	379	22	93	93	NUM
fnp-3050	379	23	%	%	NOUN
fnp-3050	379	24	[	[	X
fnp-3050	379	25	238	238	NUM
fnp-3050	379	26	]	]	PUNCT
fnp-3050	379	27	.	.	PUNCT
fnp-3050	380	1	meta	meta	VERB
fnp-3050	380	2	-	-	PUNCT
fnp-3050	380	3	analysis	analysis	NOUN
fnp-3050	380	4	of	of	ADP
fnp-3050	380	5	20	20	NUM
fnp-3050	380	6	(	(	PUNCT
fnp-3050	380	7	out	out	ADP
fnp-3050	380	8	of	of	ADP
fnp-3050	380	9	1,189	1,189	NUM
fnp-3050	380	10	)	)	PUNCT
fnp-3050	380	11	studies	study	NOUN
fnp-3050	380	12	to	to	PART
fnp-3050	380	13	distinguish	distinguish	VERB
fnp-3050	380	14	autopsy	autopsy	ADJ
fnp-3050	380	15	-	-	PUNCT
fnp-3050	380	16	verified	verify	VERB
fnp-3050	380	17	ad	ad	NOUN
fnp-3050	380	18	from	from	ADP
fnp-3050	380	19	other	other	ADJ
fnp-3050	380	20	dementias	dementia	NOUN
fnp-3050	380	21	or	or	CCONJ
fnp-3050	380	22	healthy	healthy	ADJ
fnp-3050	380	23	controls	control	NOUN
fnp-3050	380	24	showed	show	VERB
fnp-3050	380	25	a	a	DET
fnp-3050	380	26	sensitivity	sensitivity	NOUN
fnp-3050	380	27	of	of	ADP
fnp-3050	380	28	85.4	85.4	NUM
fnp-3050	380	29	%	%	NOUN
fnp-3050	380	30	(	(	PUNCT
fnp-3050	380	31	95	95	NUM
fnp-3050	380	32	%	%	NOUN
fnp-3050	380	33	ci	ci	NOUN
fnp-3050	380	34	80.8	80.8	NUM
fnp-3050	380	35	-	-	SYM
fnp-3050	380	36	90	90	NUM
fnp-3050	380	37	%	%	NOUN
fnp-3050	380	38	)	)	PUNCT
fnp-3050	380	39	and	and	CCONJ
fnp-3050	380	40	a	a	DET
fnp-3050	380	41	specificity	specificity	NOUN
fnp-3050	380	42	of	of	ADP
fnp-3050	380	43	77.7	77.7	NUM
fnp-3050	380	44	%	%	NOUN
fnp-3050	380	45	(	(	PUNCT
fnp-3050	380	46	95	95	NUM
fnp-3050	380	47	%	%	NOUN
fnp-3050	380	48	ci	ci	NOUN
fnp-3050	380	49	70.2	70.2	NUM
fnp-3050	380	50	-	-	SYM
fnp-3050	380	51	85.1	85.1	NUM
fnp-3050	380	52	%	%	NOUN
fnp-3050	380	53	)	)	PUNCT
fnp-3050	380	54	.	.	PUNCT
fnp-3050	381	1	values	value	NOUN
fnp-3050	381	2	were	be	AUX
fnp-3050	381	3	higher	high	ADJ
fnp-3050	381	4	for	for	ADP
fnp-3050	381	5	neuroimaging	neuroimaging	NOUN
fnp-3050	381	6	procedures	procedure	NOUN
fnp-3050	381	7	and	and	CCONJ
fnp-3050	381	8	slightly	slightly	ADV
fnp-3050	381	9	lower	low	ADJ
fnp-3050	381	10	for	for	ADP
fnp-3050	381	11	csf	csf	ADJ
fnp-3050	381	12	biomarkers	biomarker	NOUN
fnp-3050	381	13	,	,	PUNCT
fnp-3050	381	14	while	while	SCONJ
fnp-3050	381	15	the	the	DET
fnp-3050	381	16	combination	combination	NOUN
fnp-3050	381	17	of	of	ADP
fnp-3050	381	18	both	both	PRON
fnp-3050	381	19	resulted	result	VERB
fnp-3050	381	20	in	in	ADP
fnp-3050	381	21	better	well	ADJ
fnp-3050	381	22	results	result	NOUN
fnp-3050	381	23	[	[	X
fnp-3050	381	24	239	239	NUM
fnp-3050	381	25	]	]	PUNCT
fnp-3050	381	26	.	.	PUNCT
fnp-3050	382	1	3	3	X
fnp-3050	382	2	.	.	X
fnp-3050	382	3	pathobiological	pathobiological	ADJ
fnp-3050	382	4	subtypes	subtype	NOUN
fnp-3050	382	5	of	of	ADP
fnp-3050	382	6	ad	ad	NOUN
fnp-3050	382	7	recent	recent	ADJ
fnp-3050	382	8	studies	study	NOUN
fnp-3050	382	9	showed	show	VERB
fnp-3050	382	10	that	that	SCONJ
fnp-3050	382	11	the	the	DET
fnp-3050	382	12	neuropathology	neuropathology	NOUN
fnp-3050	382	13	of	of	ADP
fnp-3050	382	14	ad	ad	NOUN
fnp-3050	382	15	is	be	AUX
fnp-3050	382	16	heterogenous	heterogenous	ADJ
fnp-3050	382	17	[	[	X
fnp-3050	382	18	240	240	NUM
fnp-3050	382	19	-	-	NUM
fnp-3050	382	20	242	242	NUM
fnp-3050	382	21	]	]	PUNCT
fnp-3050	382	22	.	.	PUNCT
fnp-3050	383	1	the	the	DET
fnp-3050	383	2	current	current	ADJ
fnp-3050	383	3	guidelines	guideline	NOUN
fnp-3050	383	4	for	for	ADP
fnp-3050	383	5	the	the	DET
fnp-3050	383	6	neuropathological	neuropathological	ADJ
fnp-3050	383	7	diagnosis	diagnosis	NOUN
fnp-3050	383	8	of	of	ADP
fnp-3050	383	9	ad	ad	NOUN
fnp-3050	383	10	only	only	ADV
fnp-3050	383	11	consider	consider	VERB
fnp-3050	383	12	the	the	DET
fnp-3050	383	13	classical	classical	ADJ
fnp-3050	383	14	“	"	PUNCT
fnp-3050	383	15	plaque	plaque	NOUN
fnp-3050	383	16	and	and	CCONJ
fnp-3050	383	17	tangle	tangle	NOUN
fnp-3050	383	18	”	"	PUNCT
fnp-3050	383	19	phenotype	phenotype	NOUN
fnp-3050	383	20	but	but	CCONJ
fnp-3050	383	21	not	not	PART
fnp-3050	383	22	other	other	ADJ
fnp-3050	383	23	subtypes	subtype	NOUN
fnp-3050	383	24	such	such	ADJ
fnp-3050	383	25	as	as	ADP
fnp-3050	383	26	the	the	DET
fnp-3050	383	27	“	"	PUNCT
fnp-3050	383	28	plaque	plaque	NOUN
fnp-3050	383	29	only	only	ADV
fnp-3050	383	30	but	but	CCONJ
fnp-3050	383	31	without	without	ADP
fnp-3050	383	32	tangle	tangle	NOUN
fnp-3050	383	33	formation	formation	NOUN
fnp-3050	383	34	/	/	SYM
fnp-3050	383	35	predominant	predominant	ADJ
fnp-3050	383	36	”	"	PUNCT
fnp-3050	383	37	type	type	NOUN
fnp-3050	383	38	with	with	ADP
fnp-3050	383	39	abundant	abundant	ADJ
fnp-3050	383	40	amyloid	amyloid	NOUN
fnp-3050	383	41	,	,	PUNCT
fnp-3050	383	42	or	or	CCONJ
fnp-3050	383	43	the	the	DET
fnp-3050	383	44	“	"	PUNCT
fnp-3050	383	45	little	little	ADJ
fnp-3050	383	46	or	or	CCONJ
fnp-3050	383	47	no	no	PRON
fnp-3050	383	48	tau	tau	PROPN
fnp-3050	383	49	pathology	pathology	NOUN
fnp-3050	383	50	”	"	PUNCT
fnp-3050	383	51	type	type	NOUN
fnp-3050	383	52	limited	limit	VERB
fnp-3050	383	53	to	to	ADP
fnp-3050	383	54	the	the	DET
fnp-3050	383	55	hippocampus	hippocampus	NOUN
fnp-3050	383	56	and	and	CCONJ
fnp-3050	383	57	abnormal	abnormal	ADJ
fnp-3050	383	58	hp	hp	NOUN
fnp-3050	383	59	-	-	NOUN
fnp-3050	383	60	tau	tau	PROPN
fnp-3050	383	61	in	in	ADP
fnp-3050	383	62	neocortical	neocortical	ADJ
fnp-3050	383	63	pyramidal	pyramidal	ADJ
fnp-3050	383	64	cells	cell	NOUN
fnp-3050	383	65	.	.	PUNCT
fnp-3050	384	1	this	this	DET
fnp-3050	384	2	type	type	NOUN
fnp-3050	384	3	,	,	PUNCT
fnp-3050	384	4	observed	observe	VERB
fnp-3050	384	5	in	in	ADP
fnp-3050	384	6	3.4	3.4	NUM
fnp-3050	384	7	-	-	SYM
fnp-3050	384	8	8.0	8.0	NUM
fnp-3050	384	9	%	%	NOUN
fnp-3050	384	10	of	of	ADP
fnp-3050	384	11	demented	demented	ADJ
fnp-3050	384	12	subjects	subject	NOUN
fnp-3050	384	13	over	over	ADP
fnp-3050	384	14	age	age	NOUN
fnp-3050	384	15	85	85	NUM
fnp-3050	384	16	years	year	NOUN
fnp-3050	385	1	[	[	X
fnp-3050	385	2	243	243	NUM
fnp-3050	385	3	]	]	PUNCT
fnp-3050	385	4	,	,	PUNCT
fnp-3050	385	5	frequently	frequently	ADV
fnp-3050	385	6	represents	represent	VERB
fnp-3050	385	7	a	a	DET
fnp-3050	385	8	specific	specific	ADJ
fnp-3050	385	9	type	type	NOUN
fnp-3050	385	10	of	of	ADP
fnp-3050	385	11	dementia	dementia	NOUN
fnp-3050	385	12	with	with	ADP
fnp-3050	385	13	lewy	lewy	ADJ
fnp-3050	385	14	bodies	body	NOUN
fnp-3050	385	15	(	(	PUNCT
fnp-3050	385	16	dlb)/dlb	dlb)/dlb	NOUN
fnp-3050	385	17	-	-	NOUN
fnp-3050	385	18	ad	ad	NOUN
fnp-3050	385	19	[	[	X
fnp-3050	385	20	244	244	NUM
fnp-3050	385	21	]	]	PUNCT
fnp-3050	385	22	.	.	PUNCT
fnp-3050	386	1	the	the	DET
fnp-3050	386	2	recently	recently	ADV
fnp-3050	386	3	described	describe	VERB
fnp-3050	386	4	“	"	PUNCT
fnp-3050	386	5	primary	primary	ADJ
fnp-3050	386	6	age	age	NOUN
fnp-3050	386	7	-	-	PUNCT
fnp-3050	386	8	related	relate	VERB
fnp-3050	386	9	taupathy	taupathy	ADJ
fnp-3050	386	10	”	"	PUNCT
fnp-3050	386	11	(	(	PUNCT
fnp-3050	386	12	part	part	NOUN
fnp-3050	386	13	)	)	PUNCT
fnp-3050	387	1	[	[	X
fnp-3050	387	2	245	245	NUM
fnp-3050	387	3	]	]	PUNCT
fnp-3050	387	4	,	,	PUNCT
fnp-3050	387	5	previously	previously	ADV
fnp-3050	387	6	referred	refer	VERB
fnp-3050	387	7	to	to	ADP
fnp-3050	387	8	as	as	ADP
fnp-3050	387	9	“	"	PUNCT
fnp-3050	387	10	nft	nft	PROPN
fnp-3050	387	11	-	-	PUNCT
fnp-3050	387	12	predominant	predominant	ADJ
fnp-3050	387	13	dementia	dementia	NOUN
fnp-3050	387	14	”	"	PUNCT
fnp-3050	388	1	[	[	X
fnp-3050	388	2	246	246	NUM
fnp-3050	388	3	]	]	PUNCT
fnp-3050	388	4	,	,	PUNCT
fnp-3050	388	5	involves	involve	VERB
fnp-3050	388	6	people	people	NOUN
fnp-3050	388	7	over	over	ADP
fnp-3050	388	8	85	85	NUM
fnp-3050	388	9	years	year	NOUN
fnp-3050	388	10	old	old	ADJ
fnp-3050	388	11	and	and	CCONJ
fnp-3050	388	12	is	be	AUX
fnp-3050	388	13	associated	associate	VERB
fnp-3050	388	14	with	with	ADP
fnp-3050	388	15	mild	mild	ADJ
fnp-3050	388	16	to	to	AUX
fnp-3050	388	17	moderate	moderate	ADJ
fnp-3050	388	18	cognitive	cognitive	ADJ
fnp-3050	388	19	impairment	impairment	NOUN
fnp-3050	389	1	[	[	X
fnp-3050	389	2	247	247	NUM
fnp-3050	389	3	,	,	PUNCT
fnp-3050	389	4	248	248	NUM
fnp-3050	389	5	]	]	PUNCT
fnp-3050	389	6	it	it	PRON
fnp-3050	389	7	reveals	reveal	VERB
fnp-3050	389	8	tau	tau	PROPN
fnp-3050	389	9	pathology	pathology	NOUN
fnp-3050	389	10	restricted	restrict	VERB
fnp-3050	389	11	to	to	ADP
fnp-3050	389	12	the	the	DET
fnp-3050	389	13	mtl	mtl	PROPN
fnp-3050	389	14	(	(	PUNCT
fnp-3050	389	15	braak	braak	PROPN
fnp-3050	389	16	stages	stage	NOUN
fnp-3050	389	17	0	0	NUM
fnp-3050	389	18	-	-	SYM
fnp-3050	389	19	iv	iv	NUM
fnp-3050	389	20	)	)	PUNCT
fnp-3050	389	21	,	,	PUNCT
fnp-3050	389	22	relative	relative	ADJ
fnp-3050	389	23	absence	absence	NOUN
fnp-3050	389	24	of	of	ADP
fnp-3050	389	25	amyloid	amyloid	NOUN
fnp-3050	389	26	(	(	PUNCT
fnp-3050	389	27	thal	thal	NOUN
fnp-3050	389	28	aβ	aβ	NOUN
fnp-3050	389	29	phases	phase	NOUN
fnp-3050	389	30	0	0	NUM
fnp-3050	389	31	-	-	SYM
fnp-3050	389	32	2	2	NUM
fnp-3050	389	33	)	)	PUNCT
fnp-3050	389	34	,	,	PUNCT
fnp-3050	389	35	total	total	ADJ
fnp-3050	389	36	absence	absence	NOUN
fnp-3050	389	37	of	of	ADP
fnp-3050	389	38	nps	nps	PROPN
fnp-3050	389	39	,	,	PUNCT
fnp-3050	389	40	and	and	CCONJ
fnp-3050	389	41	rare	rare	ADJ
fnp-3050	389	42	caa	caa	NOUN
fnp-3050	390	1	[	[	X
fnp-3050	390	2	249	249	NUM
fnp-3050	390	3	]	]	PUNCT
fnp-3050	390	4	.	.	PUNCT
fnp-3050	391	1	the	the	DET
fnp-3050	391	2	composition	composition	NOUN
fnp-3050	391	3	of	of	ADP
fnp-3050	391	4	nfts	nft	NOUN
fnp-3050	391	5	in	in	ADP
fnp-3050	391	6	part	part	NOUN
fnp-3050	391	7	both	both	CCONJ
fnp-3050	391	8	for	for	ADP
fnp-3050	391	9	3r	3r	NUM
fnp-3050	391	10	and	and	CCONJ
fnp-3050	391	11	4r	4r	NUM
fnp-3050	391	12	tau	tau	PROPN
fnp-3050	391	13	isoforms	isoform	NOUN
fnp-3050	391	14	is	be	AUX
fnp-3050	391	15	identical	identical	ADJ
fnp-3050	391	16	with	with	ADP
fnp-3050	391	17	those	those	PRON
fnp-3050	391	18	in	in	ADP
fnp-3050	391	19	classical	classical	ADJ
fnp-3050	391	20	ad	ad	NOUN
fnp-3050	392	1	[	[	X
fnp-3050	392	2	246	246	NUM
fnp-3050	392	3	]	]	PUNCT
fnp-3050	392	4	,	,	PUNCT
fnp-3050	392	5	while	while	SCONJ
fnp-3050	392	6	pattern	pattern	NOUN
fnp-3050	392	7	of	of	ADP
fnp-3050	392	8	hippocampal	hippocampal	ADJ
fnp-3050	392	9	tau	tau	PROPN
fnp-3050	392	10	pathology	pathology	NOUN
fnp-3050	392	11	differs	differ	VERB
fnp-3050	392	12	significantly	significantly	ADV
fnp-3050	392	13	between	between	ADP
fnp-3050	392	14	part	part	NOUN
fnp-3050	392	15	and	and	CCONJ
fnp-3050	392	16	ad	ad	NOUN
fnp-3050	393	1	[	[	X
fnp-3050	393	2	250	250	NUM
fnp-3050	393	3	,	,	PUNCT
fnp-3050	393	4	251	251	NUM
fnp-3050	393	5	]	]	PUNCT
fnp-3050	393	6	.	.	PUNCT
fnp-3050	394	1	tau	tau	PROPN
fnp-3050	394	2	aggregates	aggregate	VERB
fnp-3050	394	3	influence	influence	NOUN
fnp-3050	394	4	cognition	cognition	NOUN
fnp-3050	394	5	and	and	CCONJ
fnp-3050	394	6	hippocampal	hippocampal	ADJ
fnp-3050	394	7	atrophy	atrophy	NOUN
fnp-3050	394	8	in	in	ADP
fnp-3050	394	9	the	the	DET
fnp-3050	394	10	absence	absence	NOUN
fnp-3050	394	11	of	of	ADP
fnp-3050	394	12	aβ	aβ	NOUN
fnp-3050	394	13	[	[	X
fnp-3050	394	14	249	249	NUM
fnp-3050	394	15	]	]	PUNCT
fnp-3050	394	16	.	.	PUNCT
fnp-3050	395	1	positive	positive	ADJ
fnp-3050	395	2	correlations	correlation	NOUN
fnp-3050	395	3	were	be	AUX
fnp-3050	395	4	reported	report	VERB
fnp-3050	395	5	in	in	ADP
fnp-3050	395	6	part	part	NOUN
fnp-3050	395	7	between	between	ADP
fnp-3050	395	8	the	the	DET
fnp-3050	395	9	braak	braak	NOUN
fnp-3050	395	10	nft	nft	PROPN
fnp-3050	395	11	stage	stage	NOUN
fnp-3050	395	12	and	and	CCONJ
fnp-3050	395	13	phosphorylated	phosphorylate	VERB
fnp-3050	395	14	43	43	NUM
fnp-3050	395	15	-	-	PUNCT
fnp-3050	395	16	kda	kda	NOUN
fnp-3050	395	17	tar	tar	NOUN
fnp-3050	395	18	dna	dna	NOUN
fnp-3050	395	19	-	-	PUNCT
fnp-3050	395	20	binding	bind	VERB
fnp-3050	395	21	protein	protein	NOUN
fnp-3050	395	22	(	(	PUNCT
fnp-3050	395	23	ptdp-43	ptdp-43	NOUN
fnp-3050	395	24	)	)	PUNCT
fnp-3050	395	25	stage	stage	NOUN
fnp-3050	395	26	and	and	CCONJ
fnp-3050	395	27	density	density	NOUN
fnp-3050	395	28	[	[	X
fnp-3050	395	29	252	252	NUM
fnp-3050	395	30	]	]	PUNCT
fnp-3050	395	31	.	.	PUNCT
fnp-3050	396	1	part	part	NOUN
fnp-3050	396	2	is	be	AUX
fnp-3050	396	3	considered	consider	VERB
fnp-3050	396	4	either	either	CCONJ
fnp-3050	396	5	a	a	DET
fnp-3050	396	6	prodromal	prodromal	ADJ
fnp-3050	396	7	form	form	NOUN
fnp-3050	396	8	or	or	CCONJ
fnp-3050	396	9	a	a	DET
fnp-3050	396	10	subtype	subtype	NOUN
fnp-3050	396	11	of	of	ADP
fnp-3050	396	12	ad	ad	NOUN
fnp-3050	396	13	[	[	X
fnp-3050	396	14	253	253	NUM
fnp-3050	396	15	,	,	PUNCT
fnp-3050	396	16	254	254	NUM
fnp-3050	396	17	]	]	PUNCT
fnp-3050	396	18	(	(	PUNCT
fnp-3050	396	19	see	see	VERB
fnp-3050	396	20	table	table	NOUN
fnp-3050	396	21	3	3	NUM
fnp-3050	396	22	)	)	PUNCT
fnp-3050	396	23	.	.	PUNCT
fnp-3050	397	1	mapt	mapt	NOUN
fnp-3050	397	2	h1h1	h1h1	NOUN
fnp-3050	397	3	genotype	genotype	NOUN
fnp-3050	397	4	frequency	frequency	NOUN
fnp-3050	397	5	is	be	AUX
fnp-3050	397	6	high	high	ADJ
fnp-3050	397	7	in	in	ADP
fnp-3050	397	8	both	both	PRON
fnp-3050	397	9	part	part	NOUN
fnp-3050	397	10	and	and	CCONJ
fnp-3050	397	11	limbic	limbic	ADJ
fnp-3050	397	12	-	-	PUNCT
fnp-3050	397	13	predominant	predominant	ADJ
fnp-3050	397	14	ad	ad	NOUN
fnp-3050	397	15	(	(	PUNCT
fnp-3050	397	16	lp	lp	NOUN
fnp-3050	397	17	-	-	PUNCT
fnp-3050	397	18	ad	ad	NOUN
fnp-3050	397	19	)	)	PUNCT
fnp-3050	397	20	,	,	PUNCT
fnp-3050	397	21	and	and	CCONJ
fnp-3050	397	22	similar	similar	ADJ
fnp-3050	397	23	to	to	ADP
fnp-3050	397	24	typical	typical	ADJ
fnp-3050	397	25	ad	ad	NOUN
fnp-3050	397	26	,	,	PUNCT
fnp-3050	397	27	while	while	SCONJ
fnp-3050	397	28	apoeε4	apoeε4	PROPN
fnp-3050	397	29	is	be	AUX
fnp-3050	397	30	rather	rather	ADV
fnp-3050	397	31	rare	rare	ADJ
fnp-3050	397	32	in	in	ADP
fnp-3050	397	33	part	part	NOUN
fnp-3050	397	34	[	[	X
fnp-3050	397	35	255	255	NUM
fnp-3050	397	36	]	]	PUNCT
fnp-3050	397	37	.	.	PUNCT
fnp-3050	398	1	other	other	ADJ
fnp-3050	398	2	genetic	genetic	ADJ
fnp-3050	398	3	differences	difference	NOUN
fnp-3050	398	4	between	between	ADP
fnp-3050	398	5	part	part	NOUN
fnp-3050	398	6	and	and	CCONJ
fnp-3050	398	7	ad	ad	NOUN
fnp-3050	398	8	have	have	AUX
fnp-3050	398	9	been	be	AUX
fnp-3050	398	10	described	describe	VERB
fnp-3050	398	11	[	[	PUNCT
fnp-3050	398	12	256	256	NUM
fnp-3050	398	13	]	]	PUNCT
fnp-3050	398	14	.	.	PUNCT
fnp-3050	399	1	it	it	PRON
fnp-3050	399	2	seems	seem	VERB
fnp-3050	399	3	that	that	SCONJ
fnp-3050	399	4	lower	low	ADJ
fnp-3050	399	5	concentrations	concentration	NOUN
fnp-3050	399	6	of	of	ADP
fnp-3050	399	7	aβos	aβos	PROPN
fnp-3050	399	8	cause	cause	VERB
fnp-3050	399	9	less	less	ADV
fnp-3050	399	10	severe	severe	ADJ
fnp-3050	399	11	tau	tau	NOUN
fnp-3050	399	12	deposition	deposition	NOUN
fnp-3050	399	13	due	due	ADP
fnp-3050	399	14	to	to	ADP
fnp-3050	399	15	the	the	DET
fnp-3050	399	16	fact	fact	NOUN
fnp-3050	399	17	that	that	SCONJ
fnp-3050	399	18	they	they	PRON
fnp-3050	399	19	can	can	AUX
fnp-3050	399	20	potentiate	potentiate	VERB
fnp-3050	399	21	tau	tau	PROPN
fnp-3050	399	22	aggregation	aggregation	NOUN
fnp-3050	399	23	by	by	ADP
fnp-3050	399	24	promoting	promote	VERB
fnp-3050	399	25	tau	tau	PROPN
fnp-3050	399	26	seed	seed	NOUN
fnp-3050	399	27	uptake	uptake	ADJ
fnp-3050	399	28	[	[	X
fnp-3050	399	29	170	170	NUM
fnp-3050	399	30	]	]	PUNCT
fnp-3050	399	31	.	.	PUNCT
fnp-3050	400	1	cognitive	cognitive	ADJ
fnp-3050	400	2	decline	decline	NOUN
fnp-3050	400	3	in	in	ADP
fnp-3050	400	4	part	part	NOUN
fnp-3050	400	5	is	be	AUX
fnp-3050	400	6	usually	usually	ADV
fnp-3050	400	7	milder	mild	ADJ
fnp-3050	400	8	than	than	ADP
fnp-3050	400	9	in	in	ADP
fnp-3050	400	10	ad	ad	NOUN
fnp-3050	400	11	and	and	CCONJ
fnp-3050	400	12	correlates	correlate	VERB
fnp-3050	400	13	with	with	ADP
fnp-3050	400	14	tau	tau	PROPN
fnp-3050	400	15	burden	burden	NOUN
fnp-3050	400	16	.	.	PUNCT
fnp-3050	401	1	biomarkers	biomarker	NOUN
fnp-3050	401	2	and	and	CCONJ
fnp-3050	401	3	neuroimaging	neuroimaging	NOUN
fnp-3050	401	4	studies	study	NOUN
fnp-3050	401	5	will	will	AUX
fnp-3050	401	6	be	be	AUX
fnp-3050	401	7	important	important	ADJ
fnp-3050	401	8	to	to	PART
fnp-3050	401	9	define	define	VERB
fnp-3050	401	10	part	part	NOUN
fnp-3050	401	11	ante	ante	NOUN
fnp-3050	401	12	-	-	PUNCT
fnp-3050	401	13	mortem	mortem	NOUN
fnp-3050	401	14	and	and	CCONJ
fnp-3050	401	15	to	to	PART
fnp-3050	401	16	follow	follow	VERB
fnp-3050	401	17	its	its	PRON
fnp-3050	401	18	natural	natural	ADJ
fnp-3050	401	19	history	history	NOUN
fnp-3050	401	20	[	[	X
fnp-3050	401	21	257	257	NUM
fnp-3050	401	22	]	]	PUNCT
fnp-3050	401	23	.	.	PUNCT
fnp-3050	402	1	while	while	SCONJ
fnp-3050	402	2	the	the	DET
fnp-3050	402	3	incidence	incidence	NOUN
fnp-3050	402	4	of	of	ADP
fnp-3050	402	5	classical	classical	ADJ
fnp-3050	402	6	ad	ad	NOUN
fnp-3050	402	7	increases	increase	NOUN
fnp-3050	402	8	from	from	ADP
fnp-3050	402	9	the	the	DET
fnp-3050	402	10	7th	7th	NOUN
fnp-3050	402	11	to	to	ADP
fnp-3050	402	12	the	the	DET
fnp-3050	402	13	9th	9th	ADJ
fnp-3050	402	14	decade	decade	NOUN
fnp-3050	402	15	and	and	CCONJ
fnp-3050	402	16	later	later	ADV
fnp-3050	402	17	shows	show	VERB
fnp-3050	402	18	a	a	DET
fnp-3050	402	19	mild	mild	ADJ
fnp-3050	402	20	decrease	decrease	NOUN
fnp-3050	402	21	,	,	PUNCT
fnp-3050	402	22	the	the	DET
fnp-3050	402	23	frequency	frequency	NOUN
fnp-3050	402	24	of	of	ADP
fnp-3050	402	25	part	part	NOUN
fnp-3050	402	26	increases	increase	VERB
fnp-3050	402	27	after	after	ADP
fnp-3050	402	28	the	the	DET
fnp-3050	402	29	age	age	NOUN
fnp-3050	402	30	of	of	ADP
fnp-3050	402	31	85	85	NUM
fnp-3050	402	32	years	year	NOUN
fnp-3050	402	33	[	[	X
fnp-3050	402	34	3	3	NUM
fnp-3050	402	35	]	]	PUNCT
fnp-3050	402	36	.	.	PUNCT
fnp-3050	403	1	the	the	DET
fnp-3050	403	2	limbic	limbic	NOUN
fnp-3050	403	3	-	-	PUNCT
fnp-3050	403	4	predominant	predominant	ADJ
fnp-3050	403	5	age	age	NOUN
fnp-3050	403	6	-	-	PUNCT
fnp-3050	403	7	related	relate	VERB
fnp-3050	403	8	tdp-43	tdp-43	NOUN
fnp-3050	403	9	encephalopathy	encephalopathy	ADJ
fnp-3050	403	10	(	(	PUNCT
fnp-3050	403	11	late	late	ADJ
fnp-3050	403	12	)	)	PUNCT
fnp-3050	403	13	,	,	PUNCT
fnp-3050	403	14	a	a	DET
fnp-3050	403	15	recently	recently	ADV
fnp-3050	403	16	described	describe	VERB
fnp-3050	403	17	disease	disease	NOUN
fnp-3050	403	18	entity	entity	NOUN
fnp-3050	403	19	mainly	mainly	ADV
fnp-3050	403	20	involving	involve	VERB
fnp-3050	403	21	elderly	elderly	ADJ
fnp-3050	403	22	people	people	NOUN
fnp-3050	403	23	(	(	PUNCT
fnp-3050	403	24	>	>	SYM
fnp-3050	403	25	75	75	NUM
fnp-3050	403	26	years	year	NOUN
fnp-3050	403	27	at	at	ADP
fnp-3050	403	28	death	death	NOUN
fnp-3050	403	29	)	)	PUNCT
fnp-3050	403	30	,	,	PUNCT
fnp-3050	403	31	is	be	AUX
fnp-3050	403	32	associated	associate	VERB
fnp-3050	403	33	with	with	ADP
fnp-3050	403	34	an	an	DET
fnp-3050	403	35	amnestic	amnestic	ADJ
fnp-3050	403	36	dementia	dementia	NOUN
fnp-3050	403	37	syndrome	syndrome	NOUN
fnp-3050	403	38	that	that	PRON
fnp-3050	403	39	may	may	AUX
fnp-3050	403	40	mimic	mimic	VERB
fnp-3050	403	41	ad	ad	NOUN
fnp-3050	403	42	[	[	X
fnp-3050	403	43	258	258	NUM
fnp-3050	403	44	,	,	PUNCT
fnp-3050	403	45	259	259	NUM
fnp-3050	403	46	]	]	PUNCT
fnp-3050	403	47	.	.	PUNCT
fnp-3050	404	1	it	it	PRON
fnp-3050	404	2	shows	show	VERB
fnp-3050	404	3	pathogenic	pathogenic	ADJ
fnp-3050	404	4	mechanisms	mechanism	NOUN
fnp-3050	404	5	of	of	ADP
fnp-3050	404	6	both	both	CCONJ
fnp-3050	404	7	frontotemporal	frontotemporal	ADJ
fnp-3050	404	8	lobar	lobar	ADJ
fnp-3050	404	9	degeneration	degeneration	NOUN
fnp-3050	404	10	with	with	ADP
fnp-3050	404	11	tdp-43	tdp-43	PROPN
fnp-3050	404	12	(	(	PUNCT
fnp-3050	404	13	ftld	ftld	ADJ
fnp-3050	404	14	-	-	PUNCT
fnp-3050	404	15	tdp	tdp	NOUN
fnp-3050	404	16	)	)	PUNCT
fnp-3050	404	17	and	and	CCONJ
fnp-3050	404	18	ad	ad	NOUN
fnp-3050	404	19	,	,	PUNCT
fnp-3050	404	20	but	but	CCONJ
fnp-3050	404	21	there	there	PRON
fnp-3050	404	22	are	be	VERB
fnp-3050	404	23	different	different	ADJ
fnp-3050	404	24	molecular	molecular	ADJ
fnp-3050	404	25	patterns	pattern	NOUN
fnp-3050	404	26	of	of	ADP
fnp-3050	404	27	tdp-43	tdp-43	PROPN
fnp-3050	404	28	pathology	pathology	NOUN
fnp-3050	404	29	in	in	ADP
fnp-3050	404	30	various	various	ADJ
fnp-3050	404	31	clinical	clinical	ADJ
fnp-3050	404	32	phenotypes	phenotype	NOUN
fnp-3050	404	33	with	with	ADP
fnp-3050	404	34	a	a	DET
fnp-3050	404	35	higher	high	ADJ
fnp-3050	404	36	chance	chance	NOUN
fnp-3050	404	37	of	of	ADP
fnp-3050	404	38	ftd	ftd	NOUN
fnp-3050	404	39	-	-	PUNCT
fnp-3050	404	40	like	like	ADJ
fnp-3050	404	41	symptoms	symptom	NOUN
fnp-3050	404	42	in	in	ADP
fnp-3050	404	43	ad	ad	NOUN
fnp-3050	404	44	+	+	CCONJ
fnp-3050	404	45	full	full	ADJ
fnp-3050	404	46	-	-	PUNCT
fnp-3050	404	47	length	length	NOUN
fnp-3050	404	48	tdp-43	tdp-43	NOUN
fnp-3050	404	49	cases	case	NOUN
fnp-3050	404	50	[	[	X
fnp-3050	404	51	32	32	NUM
fnp-3050	404	52	]	]	PUNCT
fnp-3050	404	53	.	.	PUNCT
fnp-3050	405	1	recent	recent	ADJ
fnp-3050	405	2	studies	study	NOUN
fnp-3050	405	3	indicated	indicate	VERB
fnp-3050	405	4	that	that	SCONJ
fnp-3050	405	5	in	in	ADP
fnp-3050	405	6	most	most	ADJ
fnp-3050	405	7	cases	case	NOUN
fnp-3050	405	8	,	,	PUNCT
fnp-3050	405	9	limbic	limbic	NOUN
fnp-3050	405	10	-	-	PUNCT
fnp-3050	405	11	predominant	predominant	ADJ
fnp-3050	405	12	age	age	NOUN
fnp-3050	405	13	-	-	PUNCT
fnp-3050	405	14	related	relate	VERB
fnp-3050	405	15	tdp-43	tdp-43	NOUN
fnp-3050	405	16	encephalopathy	encephalopathy	ADJ
fnp-3050	405	17	(	(	PUNCT
fnp-3050	405	18	late	late	PROPN
fnp-3050	405	19	-	-	PUNCT
fnp-3050	405	20	nc	nc	NOUN
fnp-3050	405	21	)	)	PUNCT
fnp-3050	405	22	and	and	CCONJ
fnp-3050	405	23	ftld	ftld	ADJ
fnp-3050	405	24	-	-	PUNCT
fnp-3050	405	25	tdp	tdp	NOUN
fnp-3050	405	26	can	can	AUX
fnp-3050	405	27	be	be	AUX
fnp-3050	405	28	differentiated	differentiate	VERB
fnp-3050	405	29	by	by	ADP
fnp-3050	405	30	applying	apply	VERB
fnp-3050	405	31	single	single	ADJ
fnp-3050	405	32	neuropathological	neuropathological	ADJ
fnp-3050	405	33	criteria	criterion	NOUN
fnp-3050	405	34	,	,	PUNCT
fnp-3050	406	1	e.g.	e.g.	ADV
fnp-3050	406	2	,	,	PUNCT
fnp-3050	406	3	the	the	DET
fnp-3050	406	4	severity	severity	NOUN
fnp-3050	406	5	of	of	ADP
fnp-3050	406	6	cortical	cortical	ADJ
fnp-3050	406	7	tdp-43	tdp-43	NOUN
fnp-3050	406	8	inclusions	inclusion	NOUN
fnp-3050	406	9	[	[	X
fnp-3050	406	10	260	260	NUM
fnp-3050	406	11	]	]	PUNCT
fnp-3050	406	12	.	.	PUNCT
fnp-3050	407	1	biomarkers	biomarker	NOUN
fnp-3050	407	2	for	for	ADP
fnp-3050	407	3	ante	ante	NOUN
fnp-3050	407	4	-	-	PUNCT
fnp-3050	407	5	mortem	mortem	NOUN
fnp-3050	407	6	diagnosis	diagnosis	NOUN
fnp-3050	407	7	of	of	ADP
fnp-3050	407	8	this	this	DET
fnp-3050	407	9	syndrome	syndrome	NOUN
fnp-3050	407	10	are	be	AUX
fnp-3050	407	11	currently	currently	ADV
fnp-3050	407	12	not	not	PART
fnp-3050	407	13	available	available	ADJ
fnp-3050	407	14	[	[	X
fnp-3050	407	15	261	261	NUM
fnp-3050	407	16	]	]	PUNCT
fnp-3050	407	17	.	.	PUNCT
fnp-3050	408	1	recent	recent	ADJ
fnp-3050	408	2	clinicopathological	clinicopathological	ADJ
fnp-3050	408	3	studies	study	NOUN
fnp-3050	408	4	have	have	AUX
fnp-3050	408	5	enabled	enable	VERB
fnp-3050	408	6	the	the	DET
fnp-3050	408	7	identification	identification	NOUN
fnp-3050	408	8	of	of	ADP
fnp-3050	408	9	several	several	ADJ
fnp-3050	408	10	pathophysiologically	pathophysiologically	ADV
fnp-3050	408	11	defined	define	VERB
fnp-3050	408	12	subtypes	subtype	NOUN
fnp-3050	408	13	of	of	ADP
fnp-3050	408	14	ad	ad	NOUN
fnp-3050	408	15	.	.	PUNCT
fnp-3050	409	1	one	one	NUM
fnp-3050	409	2	distinguished	distinguish	VERB
fnp-3050	409	3	three	three	NUM
fnp-3050	409	4	ad	ad	NOUN
fnp-3050	409	5	subtypes	subtype	NOUN
fnp-3050	409	6	based	base	VERB
fnp-3050	409	7	on	on	ADP
fnp-3050	409	8	nft	nft	PROPN
fnp-3050	409	9	density	density	PROPN
fnp-3050	409	10	:	:	PUNCT
fnp-3050	409	11	typical	typical	ADJ
fnp-3050	409	12	ad	ad	NOUN
fnp-3050	409	13	with	with	ADP
fnp-3050	409	14	balanced	balanced	ADJ
fnp-3050	409	15	nft	nft	PROPN
fnp-3050	409	16	counts	count	NOUN
fnp-3050	409	17	in	in	ADP
fnp-3050	409	18	the	the	DET
fnp-3050	409	19	neocortex	neocortex	NOUN
fnp-3050	409	20	and	and	CCONJ
fnp-3050	409	21	hippocampus	hippocampus	PROPN
fnp-3050	409	22	(	(	PUNCT
fnp-3050	409	23	75	75	NUM
fnp-3050	409	24	%	%	NOUN
fnp-3050	409	25	)	)	PUNCT
fnp-3050	409	26	,	,	PUNCT
fnp-3050	409	27	hippocampal	hippocampal	ADJ
fnp-3050	409	28	sparing	sparing	NOUN
fnp-3050	409	29	(	(	PUNCT
fnp-3050	409	30	hcsp	hcsp	PROPN
fnp-3050	409	31	)	)	PUNCT
fnp-3050	409	32	,	,	PUNCT
fnp-3050	409	33	with	with	ADP
fnp-3050	409	34	nft	nft	PROPN
fnp-3050	409	35	counts	count	NOUN
fnp-3050	409	36	predominantly	predominantly	ADV
fnp-3050	409	37	in	in	ADP
fnp-3050	409	38	association	association	NOUN
fnp-3050	409	39	cortices	cortex	NOUN
fnp-3050	409	40	(	(	PUNCT
fnp-3050	409	41	11	11	NUM
fnp-3050	409	42	%	%	NOUN
fnp-3050	409	43	)	)	PUNCT
fnp-3050	409	44	,	,	PUNCT
fnp-3050	409	45	and	and	CCONJ
fnp-3050	409	46	limbic	limbic	NOUN
fnp-3050	409	47	-	-	PUNCT
fnp-3050	409	48	predominant	predominant	ADJ
fnp-3050	409	49	(	(	PUNCT
fnp-3050	409	50	lp	lp	NOUN
fnp-3050	409	51	)	)	PUNCT
fnp-3050	409	52	ad	ad	NOUN
fnp-3050	409	53	mainly	mainly	ADV
fnp-3050	409	54	involving	involve	VERB
fnp-3050	409	55	the	the	DET
fnp-3050	409	56	hippocampus	hippocampus	NOUN
fnp-3050	409	57	(	(	PUNCT
fnp-3050	409	58	14	14	NUM
fnp-3050	409	59	%	%	NOUN
fnp-3050	409	60	)	)	PUNCT
fnp-3050	410	1	[	[	X
fnp-3050	410	2	262	262	NUM
fnp-3050	410	3	]	]	PUNCT
fnp-3050	410	4	.	.	PUNCT
fnp-3050	411	1	these	these	DET
fnp-3050	411	2	subtypes	subtype	NOUN
fnp-3050	411	3	had	have	VERB
fnp-3050	411	4	different	different	ADJ
fnp-3050	411	5	clinical	clinical	ADJ
fnp-3050	411	6	phenotypes	phenotype	NOUN
fnp-3050	411	7	,	,	PUNCT
fnp-3050	411	8	with	with	ADP
fnp-3050	411	9	different	different	ADJ
fnp-3050	411	10	ages	age	NOUN
fnp-3050	411	11	at	at	ADP
fnp-3050	411	12	onset	onset	NOUN
fnp-3050	411	13	and	and	CCONJ
fnp-3050	411	14	rates	rate	NOUN
fnp-3050	411	15	of	of	ADP
fnp-3050	411	16	progression	progression	NOUN
fnp-3050	411	17	(	(	PUNCT
fnp-3050	411	18	fig	fig	NOUN
fnp-3050	411	19	.	.	PUNCT
fnp-3050	411	20	9	9	NUM
fnp-3050	411	21	)	)	PUNCT
fnp-3050	411	22	.	.	PUNCT
fnp-3050	412	1	patients	patient	NOUN
fnp-3050	412	2	with	with	ADP
fnp-3050	412	3	hippocampal	hippocampal	ADJ
fnp-3050	412	4	sparing	spare	VERB
fnp-3050	412	5	ad	ad	NOUN
fnp-3050	412	6	(	(	PUNCT
fnp-3050	412	7	hcsp	hcsp	NOUN
fnp-3050	412	8	-	-	PUNCT
fnp-3050	412	9	ad	ad	NOUN
fnp-3050	412	10	)	)	PUNCT
fnp-3050	412	11	were	be	AUX
fnp-3050	412	12	youngest	young	ADJ
fnp-3050	412	13	at	at	ADP
fnp-3050	412	14	onset	onset	NOUN
fnp-3050	412	15	,	,	PUNCT
fnp-3050	412	16	had	have	VERB
fnp-3050	412	17	a	a	DET
fnp-3050	412	18	higher	high	ADJ
fnp-3050	412	19	proportion	proportion	NOUN
fnp-3050	412	20	of	of	ADP
fnp-3050	412	21	men	man	NOUN
fnp-3050	412	22	,	,	PUNCT
fnp-3050	412	23	and	and	CCONJ
fnp-3050	412	24	progressed	progress	VERB
fnp-3050	412	25	more	more	ADV
fnp-3050	412	26	quickly	quickly	ADV
fnp-3050	412	27	than	than	ADP
fnp-3050	412	28	typical	typical	ADJ
fnp-3050	412	29	ad	ad	NOUN
fnp-3050	412	30	.	.	PUNCT
fnp-3050	413	1	lp	lp	ADJ
fnp-3050	413	2	-	-	PUNCT
fnp-3050	413	3	ad	ad	NOUN
fnp-3050	413	4	patients	patient	NOUN
fnp-3050	413	5	were	be	AUX
fnp-3050	413	6	older	old	ADJ
fnp-3050	413	7	,	,	PUNCT
fnp-3050	413	8	more	more	ADV
fnp-3050	413	9	often	often	ADV
fnp-3050	413	10	female	female	ADJ
fnp-3050	413	11	,	,	PUNCT
fnp-3050	413	12	and	and	CCONJ
fnp-3050	413	13	showed	show	VERB
fnp-3050	413	14	slower	slow	ADJ
fnp-3050	413	15	progression	progression	NOUN
fnp-3050	413	16	.	.	PUNCT
fnp-3050	414	1	age	age	NOUN
fnp-3050	414	2	at	at	ADP
fnp-3050	414	3	death	death	NOUN
fnp-3050	414	4	of	of	ADP
fnp-3050	414	5	the	the	DET
fnp-3050	414	6	lp	lp	ADJ
fnp-3050	414	7	form	form	NOUN
fnp-3050	414	8	was	be	AUX
fnp-3050	414	9	highest	high	ADJ
fnp-3050	414	10	,	,	PUNCT
fnp-3050	414	11	while	while	SCONJ
fnp-3050	414	12	patients	patient	NOUN
fnp-3050	414	13	with	with	ADP
fnp-3050	414	14	hcsp	hcsp	NOUN
fnp-3050	414	15	-	-	PUNCT
fnp-3050	414	16	ad	ad	NOUN
fnp-3050	414	17	were	be	AUX
fnp-3050	414	18	youngest	young	ADJ
fnp-3050	414	19	,	,	PUNCT
fnp-3050	414	20	indicating	indicate	VERB
fnp-3050	414	21	this	this	DET
fnp-3050	414	22	type	type	NOUN
fnp-3050	414	23	as	as	ADP
fnp-3050	414	24	the	the	DET
fnp-3050	414	25	most	most	ADV
fnp-3050	414	26	aggressive	aggressive	ADJ
fnp-3050	414	27	.	.	PUNCT
fnp-3050	415	1	this	this	PRON
fnp-3050	415	2	could	could	AUX
fnp-3050	415	3	be	be	AUX
fnp-3050	415	4	related	relate	VERB
fnp-3050	415	5	to	to	ADP
fnp-3050	415	6	the	the	DET
fnp-3050	415	7	contribution	contribution	NOUN
fnp-3050	415	8	of	of	ADP
fnp-3050	415	9	tdp-43	tdp-43	PROPN
fnp-3050	415	10	pathology	pathology	PROPN
fnp-3050	415	11	,	,	PUNCT
fnp-3050	415	12	hippocampal	hippocampal	ADJ
fnp-3050	415	13	sclerosis	sclerosis	NOUN
fnp-3050	415	14	,	,	PUNCT
fnp-3050	415	15	and	and	CCONJ
fnp-3050	415	16	the	the	DET
fnp-3050	415	17	microtubule	microtubule	NOUN
fnp-3050	415	18	-	-	PUNCT
fnp-3050	415	19	associated	associate	VERB
fnp-3050	415	20	protein	protein	NOUN
fnp-3050	415	21	tau	tau	PROPN
fnp-3050	415	22	(	(	PUNCT
fnp-3050	415	23	mapt	mapt	NOUN
fnp-3050	415	24	)	)	PUNCT
fnp-3050	415	25	h1h1	h1h1	NOUN
fnp-3050	415	26	genotype	genotype	NOUN
fnp-3050	415	27	to	to	ADP
fnp-3050	415	28	lp	lp	NOUN
fnp-3050	415	29	-	-	PUNCT
fnp-3050	415	30	ad	ad	NOUN
fnp-3050	415	31	,	,	PUNCT
fnp-3050	415	32	factors	factor	NOUN
fnp-3050	415	33	related	relate	VERB
fnp-3050	415	34	to	to	ADP
fnp-3050	415	35	temporal	temporal	ADJ
fnp-3050	415	36	lobe	lobe	ADJ
fnp-3050	415	37	atrophy	atrophy	NOUN
fnp-3050	415	38	,	,	PUNCT
fnp-3050	415	39	older	old	ADJ
fnp-3050	415	40	age	age	NOUN
fnp-3050	415	41	,	,	PUNCT
fnp-3050	415	42	and	and	CCONJ
fnp-3050	415	43	slower	slow	ADJ
fnp-3050	415	44	disease	disease	NOUN
fnp-3050	415	45	progression	progression	NOUN
fnp-3050	415	46	.	.	PUNCT
fnp-3050	416	1	apoeε4	apoeε4	NOUN
fnp-3050	416	2	carriers	carrier	NOUN
fnp-3050	416	3	more	more	ADV
fnp-3050	416	4	frequently	frequently	ADV
fnp-3050	416	5	had	have	VERB
fnp-3050	416	6	lp	lp	NOUN
fnp-3050	416	7	-	-	PUNCT
fnp-3050	416	8	ad	ad	NOUN
fnp-3050	416	9	and	and	CCONJ
fnp-3050	416	10	typical	typical	ADJ
fnp-3050	416	11	ad	ad	NOUN
fnp-3050	416	12	,	,	PUNCT
fnp-3050	416	13	whereas	whereas	SCONJ
fnp-3050	416	14	non	non	NOUN
fnp-3050	416	15	-	-	NOUN
fnp-3050	416	16	carriers	carrier	NOUN
fnp-3050	416	17	more	more	ADV
fnp-3050	416	18	frequently	frequently	ADV
fnp-3050	416	19	presented	present	VERB
fnp-3050	416	20	as	as	ADP
fnp-3050	416	21	hcsp	hcsp	NOUN
fnp-3050	416	22	-	-	PUNCT
fnp-3050	416	23	ad	ad	NOUN
fnp-3050	416	24	.	.	PUNCT
fnp-3050	417	1	vascular	vascular	ADJ
fnp-3050	417	2	co	co	NOUN
fnp-3050	417	3	-	-	NOUN
fnp-3050	417	4	pathology	pathology	NOUN
fnp-3050	417	5	(	(	PUNCT
fnp-3050	417	6	ranging	range	VERB
fnp-3050	417	7	from	from	ADP
fnp-3050	417	8	16	16	NUM
fnp-3050	417	9	to	to	PART
fnp-3050	417	10	36	36	NUM
fnp-3050	417	11	%	%	NOUN
fnp-3050	417	12	)	)	PUNCT
fnp-3050	417	13	was	be	AUX
fnp-3050	417	14	highest	high	ADJ
fnp-3050	417	15	in	in	ADP
fnp-3050	417	16	the	the	DET
fnp-3050	417	17	lp	lp	NOUN
fnp-3050	417	18	and	and	CCONJ
fnp-3050	417	19	lowest	low	ADJ
fnp-3050	417	20	in	in	ADP
fnp-3050	417	21	the	the	DET
fnp-3050	417	22	hcsp	hcsp	NOUN
fnp-3050	417	23	cases	case	NOUN
fnp-3050	417	24	.	.	PUNCT
fnp-3050	418	1	typical	typical	ADJ
fnp-3050	418	2	ad	ad	NOUN
fnp-3050	418	3	had	have	VERB
fnp-3050	418	4	higher	high	ADJ
fnp-3050	418	5	ap	ap	PROPN
fnp-3050	418	6	burden	burden	NOUN
fnp-3050	418	7	in	in	ADP
fnp-3050	418	8	occipital	occipital	ADJ
fnp-3050	418	9	regions	region	NOUN
fnp-3050	418	10	compared	compare	VERB
fnp-3050	418	11	with	with	ADP
fnp-3050	418	12	lp	lp	NOUN
fnp-3050	418	13	-	-	NOUN
fnp-3050	418	14	ad	ad	NOUN
fnp-3050	418	15	[	[	X
fnp-3050	418	16	262	262	NUM
fnp-3050	418	17	]	]	PUNCT
fnp-3050	418	18	,	,	PUNCT
fnp-3050	418	19	while	while	SCONJ
fnp-3050	418	20	in	in	ADP
fnp-3050	418	21	contrast	contrast	NOUN
fnp-3050	418	22	to	to	ADP
fnp-3050	418	23	specific	specific	ADJ
fnp-3050	418	24	tau	tau	PROPN
fnp-3050	418	25	accumulation	accumulation	NOUN
fnp-3050	418	26	and	and	CCONJ
fnp-3050	418	27	brain	brain	NOUN
fnp-3050	418	28	atrophy	atrophy	NOUN
fnp-3050	418	29	patterns	pattern	NOUN
fnp-3050	418	30	among	among	ADP
fnp-3050	418	31	ad	ad	NOUN
fnp-3050	418	32	variants	variant	NOUN
fnp-3050	418	33	,	,	PUNCT
fnp-3050	418	34	aβ	aβ	DET
fnp-3050	418	35	accumulation	accumulation	NOUN
fnp-3050	418	36	appeared	appear	VERB
fnp-3050	418	37	rather	rather	ADV
fnp-3050	418	38	diffuse	diffuse	NOUN
fnp-3050	418	39	and	and	CCONJ
fnp-3050	418	40	similarly	similarly	ADV
fnp-3050	418	41	across	across	ADP
fnp-3050	418	42	groups	group	NOUN
fnp-3050	418	43	,	,	PUNCT
fnp-3050	418	44	except	except	SCONJ
fnp-3050	418	45	the	the	DET
fnp-3050	418	46	ma	ma	PROPN
fnp-3050	418	47	group	group	NOUN
fnp-3050	419	1	[	[	X
fnp-3050	419	2	263	263	NUM
fnp-3050	419	3	,	,	PUNCT
fnp-3050	419	4	264	264	NUM
fnp-3050	419	5	]	]	PUNCT
fnp-3050	419	6	.	.	PUNCT
fnp-3050	420	1	tau	tau	PROPN
fnp-3050	420	2	pathology	pathology	PROPN
fnp-3050	420	3	was	be	AUX
fnp-3050	420	4	closely	closely	ADV
fnp-3050	420	5	associated	associate	VERB
fnp-3050	420	6	with	with	ADP
fnp-3050	420	7	sites	site	NOUN
fnp-3050	420	8	of	of	ADP
fnp-3050	420	9	neurodegeneration	neurodegeneration	NOUN
fnp-3050	420	10	and	and	CCONJ
fnp-3050	420	11	brain	brain	NOUN
fnp-3050	420	12	atrophy	atrophy	NOUN
fnp-3050	420	13	corresponded	correspond	VERB
fnp-3050	420	14	well	well	ADV
fnp-3050	420	15	with	with	ADP
fnp-3050	420	16	nft	nft	PROPN
fnp-3050	420	17	topography	topography	NOUN
fnp-3050	420	18	and	and	CCONJ
fnp-3050	420	19	neuronal	neuronal	ADJ
fnp-3050	420	20	loss	loss	NOUN
fnp-3050	420	21	.	.	PUNCT
fnp-3050	421	1	[	[	X
fnp-3050	421	2	265	265	NUM
fnp-3050	421	3	-	-	SYM
fnp-3050	421	4	267	267	NUM
fnp-3050	421	5	]	]	PUNCT
fnp-3050	421	6	.	.	PUNCT
fnp-3050	422	1	clinical	clinical	ADJ
fnp-3050	422	2	symptoms	symptom	NOUN
fnp-3050	422	3	correlate	correlate	VERB
fnp-3050	422	4	with	with	ADP
fnp-3050	422	5	neuronal	neuronal	ADJ
fnp-3050	422	6	hypometabolism	hypometabolism	NOUN
fnp-3050	422	7	[	[	X
fnp-3050	422	8	262	262	NUM
fnp-3050	422	9	,	,	PUNCT
fnp-3050	422	10	268	268	NUM
fnp-3050	422	11	,	,	PUNCT
fnp-3050	422	12	269	269	NUM
fnp-3050	422	13	]	]	PUNCT
fnp-3050	422	14	.	.	PUNCT
fnp-3050	423	1	similar	similar	ADJ
fnp-3050	423	2	results	result	NOUN
fnp-3050	423	3	were	be	AUX
fnp-3050	423	4	reported	report	VERB
fnp-3050	423	5	in	in	ADP
fnp-3050	423	6	a	a	DET
fnp-3050	423	7	study	study	NOUN
fnp-3050	423	8	of	of	ADP
fnp-3050	423	9	933	933	NUM
fnp-3050	423	10	autopsy	autopsy	ADJ
fnp-3050	423	11	cases	case	NOUN
fnp-3050	423	12	of	of	ADP
fnp-3050	423	13	ad	ad	NOUN
fnp-3050	423	14	,	,	PUNCT
fnp-3050	423	15	all	all	PRON
fnp-3050	423	16	with	with	ADP
fnp-3050	423	17	neuritic	neuritic	ADJ
fnp-3050	423	18	braak	braak	NOUN
fnp-3050	423	19	stage	stage	NOUN
fnp-3050	423	20	>	>	X
fnp-3050	423	21	iv	iv	NUM
fnp-3050	424	1	[	[	X
fnp-3050	424	2	270	270	NUM
fnp-3050	424	3	]	]	PUNCT
fnp-3050	424	4	.	.	PUNCT
fnp-3050	425	1	typical	typical	ADJ
fnp-3050	425	2	ad	ad	NOUN
fnp-3050	425	3	was	be	AUX
fnp-3050	425	4	more	more	ADV
fnp-3050	425	5	frequent	frequent	ADJ
fnp-3050	425	6	than	than	ADP
fnp-3050	425	7	in	in	ADP
fnp-3050	425	8	the	the	DET
fnp-3050	425	9	mayo	mayo	NOUN
fnp-3050	425	10	series	series	NOUN
fnp-3050	425	11	(	(	PUNCT
fnp-3050	425	12	82.5	82.5	NUM
fnp-3050	425	13	vs	vs	ADP
fnp-3050	425	14	75	75	NUM
fnp-3050	425	15	%	%	NOUN
fnp-3050	425	16	)	)	PUNCT
fnp-3050	425	17	,	,	PUNCT
fnp-3050	425	18	while	while	SCONJ
fnp-3050	425	19	the	the	DET
fnp-3050	425	20	other	other	ADJ
fnp-3050	425	21	two	two	NUM
fnp-3050	425	22	subtypes	subtype	NOUN
fnp-3050	425	23	were	be	AUX
fnp-3050	425	24	slightly	slightly	ADV
fnp-3050	425	25	less	less	ADV
fnp-3050	425	26	frequent	frequent	ADJ
fnp-3050	425	27	.	.	PUNCT
fnp-3050	426	1	minimal	minimal	ADJ
fnp-3050	426	2	-	-	PUNCT
fnp-3050	426	3	atrophy	atrophy	NOUN
fnp-3050	426	4	ad	ad	NOUN
fnp-3050	426	5	(	(	PUNCT
fnp-3050	426	6	ma	ma	NOUN
fnp-3050	426	7	-	-	NOUN
fnp-3050	426	8	ad	ad	NOUN
fnp-3050	426	9	)	)	PUNCT
fnp-3050	426	10	was	be	AUX
fnp-3050	426	11	not	not	PART
fnp-3050	426	12	included	include	VERB
fnp-3050	426	13	in	in	ADP
fnp-3050	426	14	this	this	DET
fnp-3050	426	15	study	study	NOUN
fnp-3050	426	16	.	.	PUNCT
fnp-3050	427	1	the	the	DET
fnp-3050	427	2	lp	lp	ADJ
fnp-3050	427	3	-	-	PUNCT
fnp-3050	427	4	ad	ad	NOUN
fnp-3050	427	5	cases	case	NOUN
fnp-3050	427	6	shared	share	VERB
fnp-3050	427	7	some	some	DET
fnp-3050	427	8	morphological	morphological	ADJ
fnp-3050	427	9	features	feature	NOUN
fnp-3050	427	10	with	with	ADP
fnp-3050	427	11	part	part	NOUN
fnp-3050	427	12	[	[	X
fnp-3050	427	13	245	245	NUM
fnp-3050	427	14	]	]	PUNCT
fnp-3050	427	15	,	,	PUNCT
fnp-3050	427	16	although	although	SCONJ
fnp-3050	427	17	later	later	ADJ
fnp-3050	427	18	studies	study	NOUN
fnp-3050	427	19	demonstrated	demonstrate	VERB
fnp-3050	427	20	significant	significant	ADJ
fnp-3050	427	21	pathological	pathological	ADJ
fnp-3050	427	22	differences	difference	NOUN
fnp-3050	427	23	between	between	ADP
fnp-3050	427	24	part	part	NOUN
fnp-3050	427	25	and	and	CCONJ
fnp-3050	427	26	lp	lp	NOUN
fnp-3050	427	27	-	-	NOUN
fnp-3050	427	28	ad	ad	NOUN
fnp-3050	428	1	[	[	X
fnp-3050	428	2	240	240	NUM
fnp-3050	428	3	]	]	PUNCT
fnp-3050	428	4	.	.	PUNCT
fnp-3050	429	1	figure	figure	NOUN
fnp-3050	429	2	9	9	NUM
fnp-3050	429	3	.	.	PUNCT
fnp-3050	429	4	main	main	ADJ
fnp-3050	429	5	factors	factor	NOUN
fnp-3050	429	6	and	and	CCONJ
fnp-3050	429	7	characteristics	characteristic	NOUN
fnp-3050	429	8	of	of	ADP
fnp-3050	429	9	the	the	DET
fnp-3050	429	10	four	four	NUM
fnp-3050	429	11	major	major	ADJ
fnp-3050	429	12	subtypes	subtype	NOUN
fnp-3050	429	13	of	of	ADP
fnp-3050	429	14	ad	ad	NOUN
fnp-3050	429	15	.	.	PUNCT
fnp-3050	430	1	ad	ad	NOUN
fnp-3050	430	2	:	:	PUNCT
fnp-3050	430	3	alzheimer	alzheimer	PROPN
fnp-3050	430	4	’s	’s	PART
fnp-3050	430	5	disease	disease	NOUN
fnp-3050	430	6	;	;	PUNCT
fnp-3050	430	7	nft	nft	PROPN
fnp-3050	430	8	:	:	PUNCT
fnp-3050	430	9	neurofibrillary	neurofibrillary	ADJ
fnp-3050	430	10	tangle	tangle	NOUN
fnp-3050	430	11	;	;	PUNCT
fnp-3050	430	12	wmh	wmh	NOUN
fnp-3050	430	13	:	:	PUNCT
fnp-3050	430	14	white	white	ADJ
fnp-3050	430	15	matter	matter	NOUN
fnp-3050	430	16	hyperintensity	hyperintensity	NOUN
fnp-3050	430	17	;	;	PUNCT
fnp-3050	430	18	caa	caa	NOUN
fnp-3050	430	19	:	:	PUNCT
fnp-3050	430	20	cerebral	cerebral	ADJ
fnp-3050	430	21	amyloid	amyloid	NOUN
fnp-3050	430	22	angiopathy	angiopathy	NOUN
fnp-3050	430	23	;	;	PUNCT
fnp-3050	430	24	eoad	eoad	NOUN
fnp-3050	430	25	:	:	PUNCT
fnp-3050	430	26	early	early	ADJ
fnp-3050	430	27	-	-	PUNCT
fnp-3050	430	28	onset	onset	NOUN
fnp-3050	430	29	alzheimer	alzheimer	PROPN
fnp-3050	430	30	’s	’s	PART
fnp-3050	430	31	disease	disease	NOUN
fnp-3050	430	32	;	;	PUNCT
fnp-3050	430	33	load	load	NOUN
fnp-3050	430	34	:	:	PUNCT
fnp-3050	430	35	late	late	ADJ
fnp-3050	430	36	-	-	PUNCT
fnp-3050	430	37	onset	onset	NOUN
fnp-3050	430	38	alzheimer	alzheimer	PROPN
fnp-3050	430	39	’s	’s	PART
fnp-3050	430	40	disease	disease	NOUN
fnp-3050	430	41	;	;	PUNCT
fnp-3050	430	42	lp	lp	ADJ
fnp-3050	430	43	-	-	PUNCT
fnp-3050	430	44	ad	ad	NOUN
fnp-3050	430	45	:	:	PUNCT
fnp-3050	430	46	limbic	limbic	ADJ
fnp-3050	430	47	-	-	PUNCT
fnp-3050	430	48	predominant	predominant	ADJ
fnp-3050	430	49	ad	ad	NOUN
fnp-3050	430	50	.	.	PUNCT
fnp-3050	431	1	typical	typical	ADJ
fnp-3050	431	2	ad	ad	NOUN
fnp-3050	431	3	showed	show	VERB
fnp-3050	431	4	greater	great	ADJ
fnp-3050	431	5	white	white	ADJ
fnp-3050	431	6	matter	matter	NOUN
fnp-3050	431	7	hyperintensity	hyperintensity	NOUN
fnp-3050	431	8	(	(	PUNCT
fnp-3050	431	9	wmh	wmh	NOUN
fnp-3050	431	10	)	)	PUNCT
fnp-3050	431	11	burden	burden	NOUN
fnp-3050	431	12	,	,	PUNCT
fnp-3050	431	13	which	which	PRON
fnp-3050	431	14	may	may	AUX
fnp-3050	431	15	be	be	AUX
fnp-3050	431	16	due	due	ADJ
fnp-3050	431	17	to	to	ADP
fnp-3050	431	18	wallerian	wallerian	ADJ
fnp-3050	431	19	degeneration	degeneration	NOUN
fnp-3050	431	20	induced	induce	VERB
fnp-3050	431	21	by	by	ADP
fnp-3050	431	22	cortical	cortical	ADJ
fnp-3050	431	23	tau	tau	PROPN
fnp-3050	431	24	pathology	pathology	NOUN
fnp-3050	431	25	[	[	X
fnp-3050	431	26	271	271	NUM
fnp-3050	431	27	,	,	PUNCT
fnp-3050	431	28	272	272	NUM
fnp-3050	431	29	]	]	PUNCT
fnp-3050	431	30	,	,	PUNCT
fnp-3050	431	31	small	small	ADJ
fnp-3050	431	32	vessel	vessel	NOUN
fnp-3050	431	33	disease	disease	NOUN
fnp-3050	431	34	,	,	PUNCT
fnp-3050	431	35	or	or	CCONJ
fnp-3050	431	36	both	both	PRON
fnp-3050	432	1	[	[	PUNCT
fnp-3050	432	2	273	273	NUM
fnp-3050	432	3	-	-	SYM
fnp-3050	432	4	275	275	NUM
fnp-3050	432	5	]	]	PUNCT
fnp-3050	432	6	.	.	PUNCT
fnp-3050	433	1	tau	tau	PROPN
fnp-3050	433	2	pathology	pathology	NOUN
fnp-3050	433	3	and	and	CCONJ
fnp-3050	433	4	neurodegeneration	neurodegeneration	NOUN
fnp-3050	433	5	can	can	AUX
fnp-3050	433	6	disrupt	disrupt	VERB
fnp-3050	433	7	key	key	ADJ
fnp-3050	433	8	brain	brain	NOUN
fnp-3050	433	9	networks	network	NOUN
fnp-3050	433	10	,	,	PUNCT
fnp-3050	433	11	which	which	PRON
fnp-3050	433	12	may	may	AUX
fnp-3050	433	13	induce	induce	VERB
fnp-3050	433	14	memory	memory	NOUN
fnp-3050	433	15	impairment	impairment	NOUN
fnp-3050	433	16	comparable	comparable	ADJ
fnp-3050	433	17	to	to	ADP
fnp-3050	433	18	lp	lp	ADJ
fnp-3050	433	19	-	-	PUNCT
fnp-3050	433	20	ad	ad	NOUN
fnp-3050	433	21	and	and	CCONJ
fnp-3050	433	22	typical	typical	ADJ
fnp-3050	433	23	ad	ad	NOUN
fnp-3050	433	24	in	in	ADP
fnp-3050	433	25	the	the	DET
fnp-3050	433	26	absence	absence	NOUN
fnp-3050	433	27	of	of	ADP
fnp-3050	433	28	overt	overt	ADJ
fnp-3050	433	29	brain	brain	NOUN
fnp-3050	433	30	atrophy	atrophy	NOUN
fnp-3050	433	31	of	of	ADP
fnp-3050	433	32	the	the	DET
fnp-3050	433	33	mtl	mtl	PROPN
fnp-3050	433	34	in	in	ADP
fnp-3050	433	35	ma	ma	PROPN
fnp-3050	433	36	-	-	NOUN
fnp-3050	433	37	ad	ad	NOUN
fnp-3050	433	38	that	that	PRON
fnp-3050	433	39	shows	show	VERB
fnp-3050	433	40	[	[	X
fnp-3050	433	41	276	276	NUM
fnp-3050	433	42	-	-	SYM
fnp-3050	433	43	278	278	NUM
fnp-3050	433	44	]	]	PUNCT
fnp-3050	433	45	.	.	PUNCT
fnp-3050	434	1	distinct	distinct	ADJ
fnp-3050	434	2	patterns	pattern	NOUN
fnp-3050	434	3	of	of	ADP
fnp-3050	434	4	nft	nft	PROPN
fnp-3050	434	5	deposition	deposition	NOUN
fnp-3050	434	6	in	in	ADP
fnp-3050	434	7	young	young	ADJ
fnp-3050	434	8	-	-	PUNCT
fnp-3050	434	9	onset	onset	NOUN
fnp-3050	434	10	versus	versus	ADP
fnp-3050	434	11	older	old	ADJ
fnp-3050	434	12	-	-	PUNCT
fnp-3050	434	13	onset	onset	NOUN
fnp-3050	434	14	ad	ad	NOUN
fnp-3050	434	15	give	give	VERB
fnp-3050	434	16	evidence	evidence	NOUN
fnp-3050	434	17	for	for	ADP
fnp-3050	434	18	variability	variability	NOUN
fnp-3050	434	19	in	in	ADP
fnp-3050	434	20	regional	regional	ADJ
fnp-3050	434	21	deposition	deposition	NOUN
fnp-3050	434	22	patterns	pattern	NOUN
fnp-3050	434	23	and	and	CCONJ
fnp-3050	434	24	demonstrate	demonstrate	VERB
fnp-3050	434	25	that	that	SCONJ
fnp-3050	434	26	different	different	ADJ
fnp-3050	434	27	disease	disease	NOUN
fnp-3050	434	28	phenotypes	phenotype	NOUN
fnp-3050	434	29	have	have	VERB
fnp-3050	434	30	different	different	ADJ
fnp-3050	434	31	patterns	pattern	NOUN
fnp-3050	434	32	of	of	ADP
fnp-3050	434	33	tau	tau	PROPN
fnp-3050	434	34	pathology	pathology	NOUN
fnp-3050	435	1	[	[	X
fnp-3050	435	2	279	279	NUM
fnp-3050	435	3	]	]	PUNCT
fnp-3050	435	4	.	.	PUNCT
fnp-3050	436	1	other	other	ADJ
fnp-3050	436	2	atypical	atypical	ADJ
fnp-3050	436	3	non	non	ADJ
fnp-3050	436	4	-	-	ADJ
fnp-3050	436	5	amnestic	amnestic	ADJ
fnp-3050	436	6	syndromes	syndrome	NOUN
fnp-3050	436	7	,	,	PUNCT
fnp-3050	436	8	referred	refer	VERB
fnp-3050	436	9	to	to	ADP
fnp-3050	436	10	as	as	ADP
fnp-3050	436	11	focal	focal	ADJ
fnp-3050	436	12	ad	ad	NOUN
fnp-3050	436	13	[	[	X
fnp-3050	436	14	26	26	NUM
fnp-3050	436	15	,	,	PUNCT
fnp-3050	436	16	280	280	NUM
fnp-3050	436	17	,	,	PUNCT
fnp-3050	436	18	281	281	NUM
fnp-3050	436	19	]	]	PUNCT
fnp-3050	436	20	,	,	PUNCT
fnp-3050	436	21	include	include	VERB
fnp-3050	436	22	logopenic	logopenic	ADJ
fnp-3050	436	23	primary	primary	ADJ
fnp-3050	436	24	progressive	progressive	ADJ
fnp-3050	436	25	aphasia	aphasia	NOUN
fnp-3050	436	26	(	(	PUNCT
fnp-3050	436	27	lppa	lppa	ADJ
fnp-3050	436	28	)	)	PUNCT
fnp-3050	436	29	,	,	PUNCT
fnp-3050	436	30	showing	show	VERB
fnp-3050	436	31	higher	high	ADJ
fnp-3050	436	32	nft	nft	PROPN
fnp-3050	436	33	density	density	NOUN
fnp-3050	436	34	in	in	ADP
fnp-3050	436	35	superior	superior	ADJ
fnp-3050	436	36	temporal	temporal	ADJ
fnp-3050	436	37	gyrus	gyrus	NOUN
fnp-3050	436	38	but	but	CCONJ
fnp-3050	436	39	thal	thal	NOUN
fnp-3050	436	40	amyloid	amyloid	NOUN
fnp-3050	436	41	plaques	plaque	NOUN
fnp-3050	436	42	similar	similar	ADJ
fnp-3050	436	43	to	to	ADP
fnp-3050	436	44	amnestic	amnestic	ADJ
fnp-3050	436	45	ad	ad	NOUN
fnp-3050	437	1	[	[	X
fnp-3050	437	2	282	282	NUM
fnp-3050	437	3	-	-	SYM
fnp-3050	437	4	284	284	NUM
fnp-3050	437	5	]	]	PUNCT
fnp-3050	437	6	.	.	PUNCT
fnp-3050	438	1	the	the	DET
fnp-3050	438	2	proportion	proportion	NOUN
fnp-3050	438	3	of	of	ADP
fnp-3050	438	4	apoeε4	apoeε4	PROPN
fnp-3050	438	5	carriers	carrier	NOUN
fnp-3050	438	6	was	be	AUX
fnp-3050	438	7	elevated	elevate	VERB
fnp-3050	438	8	in	in	ADP
fnp-3050	438	9	amnestic	amnestic	ADJ
fnp-3050	438	10	but	but	CCONJ
fnp-3050	438	11	not	not	PART
fnp-3050	438	12	in	in	ADP
fnp-3050	438	13	non	non	ADJ
fnp-3050	438	14	-	-	ADJ
fnp-3050	438	15	amnestic	amnestic	ADJ
fnp-3050	438	16	forms	form	NOUN
fnp-3050	438	17	of	of	ADP
fnp-3050	438	18	ad	ad	NOUN
fnp-3050	438	19	,	,	PUNCT
fnp-3050	438	20	suggesting	suggest	VERB
fnp-3050	438	21	that	that	SCONJ
fnp-3050	438	22	apoe	apoe	NOUN
fnp-3050	438	23	is	be	AUX
fnp-3050	438	24	a	a	DET
fnp-3050	438	25	selective	selective	ADJ
fnp-3050	438	26	risk	risk	NOUN
fnp-3050	438	27	factor	factor	NOUN
fnp-3050	438	28	that	that	PRON
fnp-3050	438	29	increases	increase	VERB
fnp-3050	438	30	the	the	DET
fnp-3050	438	31	vulnerability	vulnerability	NOUN
fnp-3050	438	32	of	of	ADP
fnp-3050	438	33	memory	memory	NOUN
fnp-3050	438	34	-	-	PUNCT
fnp-3050	438	35	related	relate	VERB
fnp-3050	438	36	medial	medial	ADJ
fnp-3050	438	37	temporal	temporal	ADJ
fnp-3050	438	38	areas	area	NOUN
fnp-3050	438	39	rather	rather	ADV
fnp-3050	438	40	than	than	ADP
fnp-3050	438	41	language	language	NOUN
fnp-3050	438	42	-	-	PUNCT
fnp-3050	438	43	related	relate	VERB
fnp-3050	438	44	neocortices	neocortice	NOUN
fnp-3050	439	1	[	[	X
fnp-3050	439	2	285	285	NUM
fnp-3050	439	3	]	]	PUNCT
fnp-3050	439	4	.	.	PUNCT
fnp-3050	440	1	further	further	ADJ
fnp-3050	440	2	atypical	atypical	ADJ
fnp-3050	440	3	forms	form	NOUN
fnp-3050	440	4	are	be	AUX
fnp-3050	440	5	posterior	posterior	ADJ
fnp-3050	440	6	cortical	cortical	ADJ
fnp-3050	440	7	atrophy	atrophy	NOUN
fnp-3050	440	8	(	(	PUNCT
fnp-3050	440	9	pca	pca	PROPN
fnp-3050	440	10	)	)	PUNCT
fnp-3050	441	1	[	[	X
fnp-3050	441	2	286	286	NUM
fnp-3050	441	3	]	]	PUNCT
fnp-3050	441	4	,	,	PUNCT
fnp-3050	441	5	non	non	ADJ
fnp-3050	441	6	-	-	ADJ
fnp-3050	441	7	amnestic	amnestic	ADJ
fnp-3050	441	8	ad	ad	NOUN
fnp-3050	441	9	with	with	ADP
fnp-3050	441	10	tdp-43	tdp-43	PROPN
fnp-3050	441	11	pathology	pathology	NOUN
fnp-3050	442	1	[	[	X
fnp-3050	442	2	287	287	NUM
fnp-3050	442	3	]	]	PUNCT
fnp-3050	442	4	,	,	PUNCT
fnp-3050	442	5	syndromes	syndrome	NOUN
fnp-3050	442	6	resembling	resemble	VERB
fnp-3050	442	7	behavioral	behavioral	ADJ
fnp-3050	442	8	variant	variant	ADJ
fnp-3050	442	9	fronto	fronto	NOUN
fnp-3050	442	10	-	-	PUNCT
fnp-3050	442	11	temporal	temporal	ADJ
fnp-3050	442	12	lobe	lobe	NOUN
fnp-3050	442	13	degeneration	degeneration	NOUN
fnp-3050	442	14	with	with	ADP
fnp-3050	442	15	tau	tau	PROPN
fnp-3050	442	16	pathology	pathology	NOUN
fnp-3050	442	17	(	(	PUNCT
fnp-3050	442	18	bvftd	bvftd	PROPN
fnp-3050	442	19	-	-	PUNCT
fnp-3050	442	20	tau	tau	PROPN
fnp-3050	442	21	)	)	PUNCT
fnp-3050	443	1	[	[	X
fnp-3050	443	2	266	266	NUM
fnp-3050	443	3	,	,	PUNCT
fnp-3050	443	4	288	288	NUM
fnp-3050	443	5	]	]	PUNCT
fnp-3050	443	6	,	,	PUNCT
fnp-3050	443	7	and	and	CCONJ
fnp-3050	443	8	the	the	DET
fnp-3050	443	9	corticobasal	corticobasal	NOUN
fnp-3050	443	10	syndrome	syndrome	NOUN
fnp-3050	443	11	(	(	PUNCT
fnp-3050	443	12	cbs	cbs	NOUN
fnp-3050	443	13	)	)	PUNCT
fnp-3050	443	14	subtype	subtype	NOUN
fnp-3050	443	15	of	of	ADP
fnp-3050	443	16	ad	ad	NOUN
fnp-3050	443	17	that	that	PRON
fnp-3050	443	18	shows	show	VERB
fnp-3050	443	19	a	a	DET
fnp-3050	443	20	higher	high	ADJ
fnp-3050	443	21	nft	nft	PROPN
fnp-3050	443	22	density	density	NOUN
fnp-3050	443	23	in	in	ADP
fnp-3050	443	24	the	the	DET
fnp-3050	443	25	perirolandic	perirolandic	ADJ
fnp-3050	443	26	cortices	cortex	NOUN
fnp-3050	443	27	and	and	CCONJ
fnp-3050	443	28	greater	great	ADJ
fnp-3050	443	29	neuronal	neuronal	ADJ
fnp-3050	443	30	loss	loss	NOUN
fnp-3050	443	31	in	in	ADP
fnp-3050	443	32	substantia	substantia	NOUN
fnp-3050	443	33	nigra	nigra	NOUN
fnp-3050	443	34	which	which	PRON
fnp-3050	443	35	may	may	AUX
fnp-3050	443	36	contribute	contribute	VERB
fnp-3050	443	37	to	to	ADP
fnp-3050	443	38	parkinsonism	parkinsonism	NOUN
fnp-3050	443	39	that	that	PRON
fnp-3050	443	40	uncommon	uncommon	ADJ
fnp-3050	443	41	in	in	ADP
fnp-3050	443	42	classic	classic	ADJ
fnp-3050	443	43	ad	ad	NOUN
fnp-3050	444	1	[	[	X
fnp-3050	444	2	289	289	NUM
fnp-3050	444	3	]	]	PUNCT
fnp-3050	444	4	.	.	PUNCT
fnp-3050	445	1	behavioral	behavioral	ADJ
fnp-3050	445	2	/	/	SYM
fnp-3050	445	3	dysexecutive	dysexecutive	ADJ
fnp-3050	445	4	ad	ad	NOUN
fnp-3050	445	5	revealed	reveal	VERB
fnp-3050	445	6	temporo	temporo	PROPN
fnp-3050	445	7	-	-	PUNCT
fnp-3050	445	8	parietal	parietal	ADJ
fnp-3050	445	9	-	-	PUNCT
fnp-3050	445	10	predominant	predominant	ADJ
fnp-3050	445	11	atrophy	atrophy	NOUN
fnp-3050	445	12	.	.	PUNCT
fnp-3050	446	1	in	in	ADP
fnp-3050	446	2	the	the	DET
fnp-3050	446	3	mayo	mayo	NOUN
fnp-3050	446	4	series	series	PROPN
fnp-3050	446	5	,	,	PUNCT
fnp-3050	446	6	pca	pca	PROPN
fnp-3050	446	7	,	,	PUNCT
fnp-3050	446	8	lppa	lppa	ADJ
fnp-3050	446	9	and	and	CCONJ
fnp-3050	446	10	bvftd	bvftd	PROPN
fnp-3050	446	11	variants	variant	NOUN
fnp-3050	446	12	were	be	AUX
fnp-3050	446	13	more	more	ADV
fnp-3050	446	14	common	common	ADJ
fnp-3050	446	15	in	in	ADP
fnp-3050	446	16	hcsp	hcsp	NOUN
fnp-3050	446	17	-	-	PUNCT
fnp-3050	446	18	ad	ad	NOUN
fnp-3050	446	19	than	than	ADP
fnp-3050	446	20	in	in	ADP
fnp-3050	446	21	lp	lp	ADJ
fnp-3050	446	22	and	and	CCONJ
fnp-3050	446	23	typical	typical	ADJ
fnp-3050	446	24	ad	ad	NOUN
fnp-3050	446	25	[	[	X
fnp-3050	446	26	262	262	NUM
fnp-3050	446	27	,	,	PUNCT
fnp-3050	446	28	290	290	NUM
fnp-3050	446	29	]	]	PUNCT
fnp-3050	446	30	.	.	PUNCT
fnp-3050	447	1	accumulation	accumulation	NOUN
fnp-3050	447	2	of	of	ADP
fnp-3050	447	3	nfts	nft	NOUN
fnp-3050	447	4	and	and	CCONJ
fnp-3050	447	5	activated	activate	VERB
fnp-3050	447	6	hypertrophic	hypertrophic	ADJ
fnp-3050	447	7	microglia	microglia	NOUN
fnp-3050	447	8	associated	associate	VERB
fnp-3050	447	9	with	with	ADP
fnp-3050	447	10	low	low	ADJ
fnp-3050	447	11	neuron	neuron	NOUN
fnp-3050	447	12	densities	density	NOUN
fnp-3050	447	13	suggests	suggest	VERB
fnp-3050	447	14	that	that	SCONJ
fnp-3050	447	15	they	they	PRON
fnp-3050	447	16	may	may	AUX
fnp-3050	447	17	collectively	collectively	ADV
fnp-3050	447	18	contribute	contribute	VERB
fnp-3050	447	19	to	to	ADP
fnp-3050	447	20	focal	focal	ADJ
fnp-3050	447	21	neurodegeneration	neurodegeneration	NOUN
fnp-3050	447	22	characteristic	characteristic	NOUN
fnp-3050	447	23	of	of	ADP
fnp-3050	447	24	primary	primary	ADJ
fnp-3050	447	25	progressive	progressive	ADJ
fnp-3050	447	26	aphasia	aphasia	NOUN
fnp-3050	447	27	ad	ad	NOUN
fnp-3050	447	28	[	[	X
fnp-3050	447	29	291	291	NUM
fnp-3050	447	30	]	]	PUNCT
fnp-3050	447	31	.	.	PUNCT
fnp-3050	448	1	the	the	DET
fnp-3050	448	2	pathogenic	pathogenic	ADJ
fnp-3050	448	3	factors	factor	NOUN
fnp-3050	448	4	underlying	underlie	VERB
fnp-3050	448	5	ad	ad	NOUN
fnp-3050	448	6	subtypes	subtype	NOUN
fnp-3050	448	7	are	be	AUX
fnp-3050	448	8	unclear	unclear	ADJ
fnp-3050	448	9	and	and	CCONJ
fnp-3050	448	10	can	can	AUX
fnp-3050	448	11	not	not	PART
fnp-3050	448	12	be	be	AUX
fnp-3050	448	13	explained	explain	VERB
fnp-3050	448	14	by	by	ADP
fnp-3050	448	15	aβ	aβ	DET
fnp-3050	448	16	pathology	pathology	NOUN
fnp-3050	448	17	alone	alone	ADV
fnp-3050	448	18	,	,	PUNCT
fnp-3050	448	19	because	because	SCONJ
fnp-3050	448	20	the	the	DET
fnp-3050	448	21	distribution	distribution	NOUN
fnp-3050	448	22	of	of	ADP
fnp-3050	448	23	aβ	aβ	DET
fnp-3050	448	24	pet	pet	ADJ
fnp-3050	448	25	retention	retention	NOUN
fnp-3050	448	26	is	be	AUX
fnp-3050	448	27	quite	quite	ADV
fnp-3050	448	28	similar	similar	ADJ
fnp-3050	448	29	in	in	ADP
fnp-3050	448	30	all	all	DET
fnp-3050	448	31	subtypes	subtype	NOUN
fnp-3050	448	32	[	[	X
fnp-3050	448	33	263	263	NUM
fnp-3050	448	34	]	]	PUNCT
fnp-3050	448	35	.	.	PUNCT
fnp-3050	449	1	however	however	ADV
fnp-3050	449	2	,	,	PUNCT
fnp-3050	449	3	solid	solid	ADJ
fnp-3050	449	4	-	-	PUNCT
fnp-3050	449	5	state	state	NOUN
fnp-3050	449	6	nuclear	nuclear	ADJ
fnp-3050	449	7	magnetic	magnetic	ADJ
fnp-3050	449	8	resonance	resonance	NOUN
fnp-3050	449	9	measurements	measurement	NOUN
fnp-3050	449	10	showed	show	VERB
fnp-3050	449	11	qualitative	qualitative	ADJ
fnp-3050	449	12	differences	difference	NOUN
fnp-3050	449	13	between	between	ADP
fnp-3050	449	14	aβ-40	aβ-40	PRON
fnp-3050	449	15	and	and	CCONJ
fnp-3050	449	16	aβ-42	aβ-42	PUNCT
fnp-3050	449	17	aggregates	aggregate	NOUN
fnp-3050	449	18	in	in	ADP
fnp-3050	449	19	the	the	DET
fnp-3050	449	20	brain	brain	NOUN
fnp-3050	449	21	tissue	tissue	NOUN
fnp-3050	449	22	of	of	ADP
fnp-3050	449	23	patients	patient	NOUN
fnp-3050	449	24	with	with	ADP
fnp-3050	449	25	two	two	NUM
fnp-3050	449	26	atypical	atypical	ADJ
fnp-3050	449	27	ad	ad	NOUN
fnp-3050	449	28	clinical	clinical	ADJ
fnp-3050	449	29	subtypes	subtype	NOUN
fnp-3050	449	30	posterior	posterior	ADJ
fnp-3050	449	31	cortical	cortical	ADJ
fnp-3050	449	32	atrophy	atrophy	NOUN
fnp-3050	449	33	variant	variant	NOUN
fnp-3050	449	34	and	and	CCONJ
fnp-3050	449	35	a	a	DET
fnp-3050	449	36	typical	typical	ADJ
fnp-3050	449	37	prolonged	prolonged	ADJ
fnp-3050	449	38	-	-	PUNCT
fnp-3050	449	39	duration	duration	NOUN
fnp-3050	449	40	form	form	NOUN
fnp-3050	449	41	indicating	indicate	VERB
fnp-3050	449	42	that	that	SCONJ
fnp-3050	449	43	there	there	PRON
fnp-3050	449	44	are	be	VERB
fnp-3050	449	45	structural	structural	ADJ
fnp-3050	449	46	variations	variation	NOUN
fnp-3050	449	47	in	in	ADP
fnp-3050	449	48	aβ	aβ	NOUN
fnp-3050	449	49	fibrils	fibril	NOUN
fnp-3050	449	50	from	from	ADP
fnp-3050	449	51	ad	ad	NOUN
fnp-3050	449	52	clinical	clinical	ADJ
fnp-3050	449	53	subtypes	subtype	NOUN
fnp-3050	449	54	[	[	X
fnp-3050	449	55	60	60	NUM
fnp-3050	449	56	]	]	PUNCT
fnp-3050	449	57	.	.	PUNCT
fnp-3050	450	1	ma	ma	PROPN
fnp-3050	450	2	-	-	PUNCT
fnp-3050	450	3	ad	ad	NOUN
fnp-3050	450	4	,	,	PUNCT
fnp-3050	450	5	although	although	SCONJ
fnp-3050	450	6	aβ	aβ	NOUN
fnp-3050	450	7	-	-	PUNCT
fnp-3050	450	8	positive	positive	ADJ
fnp-3050	450	9	,	,	PUNCT
fnp-3050	450	10	shows	show	VERB
fnp-3050	450	11	less	less	ADJ
fnp-3050	450	12	tau	tau	PROPN
fnp-3050	450	13	pathology	pathology	NOUN
fnp-3050	450	14	.	.	PUNCT
fnp-3050	451	1	according	accord	VERB
fnp-3050	451	2	to	to	ADP
fnp-3050	451	3	recent	recent	ADJ
fnp-3050	451	4	studies	study	NOUN
fnp-3050	451	5	,	,	PUNCT
fnp-3050	451	6	ad	ad	NOUN
fnp-3050	451	7	“	"	PUNCT
fnp-3050	451	8	subtypes	subtype	NOUN
fnp-3050	451	9	”	"	PUNCT
fnp-3050	451	10	may	may	AUX
fnp-3050	451	11	be	be	AUX
fnp-3050	451	12	linked	link	VERB
fnp-3050	451	13	to	to	ADP
fnp-3050	451	14	different	different	ADJ
fnp-3050	451	15	tau	tau	PROPN
fnp-3050	451	16	protein	protein	NOUN
fnp-3050	451	17	modifications	modification	NOUN
fnp-3050	451	18	,	,	PUNCT
fnp-3050	451	19	suggesting	suggest	VERB
fnp-3050	451	20	that	that	SCONJ
fnp-3050	451	21	ad	ad	NOUN
fnp-3050	451	22	patients	patient	NOUN
fnp-3050	451	23	may	may	AUX
fnp-3050	451	24	have	have	VERB
fnp-3050	451	25	multiple	multiple	ADJ
fnp-3050	451	26	molecular	molecular	ADJ
fnp-3050	451	27	drivers	driver	NOUN
fnp-3050	451	28	of	of	ADP
fnp-3050	451	29	an	an	DET
fnp-3050	451	30	otherwise	otherwise	ADV
fnp-3050	451	31	common	common	ADJ
fnp-3050	451	32	phenotype	phenotype	NOUN
fnp-3050	451	33	[	[	X
fnp-3050	451	34	192	192	NUM
fnp-3050	451	35	]	]	PUNCT
fnp-3050	451	36	.	.	PUNCT
fnp-3050	452	1	this	this	PRON
fnp-3050	452	2	suggests	suggest	VERB
fnp-3050	452	3	that	that	SCONJ
fnp-3050	452	4	multiple	multiple	ADJ
fnp-3050	452	5	subtypes	subtype	NOUN
fnp-3050	452	6	are	be	AUX
fnp-3050	452	7	parts	part	NOUN
fnp-3050	452	8	of	of	ADP
fnp-3050	452	9	the	the	DET
fnp-3050	452	10	same	same	ADJ
fnp-3050	452	11	ad	ad	NOUN
fnp-3050	452	12	continuum	continuum	NOUN
fnp-3050	453	1	[	[	X
fnp-3050	453	2	266	266	NUM
fnp-3050	453	3	]	]	PUNCT
fnp-3050	453	4	,	,	PUNCT
fnp-3050	453	5	which	which	PRON
fnp-3050	453	6	may	may	AUX
fnp-3050	453	7	have	have	VERB
fnp-3050	453	8	consequences	consequence	NOUN
fnp-3050	453	9	for	for	ADP
fnp-3050	453	10	personalized	personalize	VERB
fnp-3050	453	11	therapeutic	therapeutic	ADJ
fnp-3050	453	12	approaches	approach	NOUN
fnp-3050	453	13	.	.	PUNCT
fnp-3050	454	1	4	4	X
fnp-3050	454	2	.	.	X
fnp-3050	454	3	the	the	DET
fnp-3050	454	4	impact	impact	NOUN
fnp-3050	454	5	of	of	ADP
fnp-3050	454	6	co	co	NOUN
fnp-3050	454	7	-	-	NOUN
fnp-3050	454	8	pathologies	pathology	NOUN
fnp-3050	454	9	ad	ad	NOUN
fnp-3050	454	10	pathology	pathology	NOUN
fnp-3050	454	11	rarely	rarely	ADV
fnp-3050	454	12	occurs	occur	VERB
fnp-3050	454	13	in	in	ADP
fnp-3050	454	14	isolation	isolation	NOUN
fnp-3050	454	15	,	,	PUNCT
fnp-3050	454	16	while	while	SCONJ
fnp-3050	454	17	complex	complex	ADJ
fnp-3050	454	18	pathologies	pathology	NOUN
fnp-3050	454	19	frequently	frequently	ADV
fnp-3050	454	20	lead	lead	VERB
fnp-3050	454	21	to	to	ADP
fnp-3050	454	22	cognitive	cognitive	ADJ
fnp-3050	454	23	decline	decline	NOUN
fnp-3050	454	24	.	.	PUNCT
fnp-3050	455	1	the	the	DET
fnp-3050	455	2	number	number	NOUN
fnp-3050	455	3	of	of	ADP
fnp-3050	455	4	co	co	NOUN
fnp-3050	455	5	-	-	NOUN
fnp-3050	455	6	morbidities	morbidity	NOUN
fnp-3050	455	7	increases	increase	VERB
fnp-3050	455	8	in	in	ADP
fnp-3050	455	9	the	the	DET
fnp-3050	455	10	aging	age	VERB
fnp-3050	455	11	brain	brain	NOUN
fnp-3050	455	12	,	,	PUNCT
fnp-3050	455	13	causing	cause	VERB
fnp-3050	455	14	mixed	mixed	ADJ
fnp-3050	455	15	pathologies	pathology	NOUN
fnp-3050	455	16	[	[	X
fnp-3050	455	17	3	3	NUM
fnp-3050	455	18	,	,	PUNCT
fnp-3050	455	19	248	248	NUM
fnp-3050	455	20	,	,	PUNCT
fnp-3050	455	21	274	274	NUM
fnp-3050	455	22	,	,	PUNCT
fnp-3050	455	23	292	292	NUM
fnp-3050	455	24	-	-	SYM
fnp-3050	455	25	298	298	NUM
fnp-3050	455	26	]	]	PUNCT
fnp-3050	455	27	.	.	PUNCT
fnp-3050	456	1	the	the	DET
fnp-3050	456	2	challenges	challenge	NOUN
fnp-3050	456	3	of	of	ADP
fnp-3050	456	4	pathological	pathological	ADJ
fnp-3050	456	5	mimics	mimic	NOUN
fnp-3050	456	6	and	and	CCONJ
fnp-3050	456	7	concomitant	concomitant	ADJ
fnp-3050	456	8	pathologies	pathology	NOUN
fnp-3050	456	9	in	in	ADP
fnp-3050	456	10	the	the	DET
fnp-3050	456	11	neuropathologic	neuropathologic	ADJ
fnp-3050	456	12	diagnosis	diagnosis	NOUN
fnp-3050	456	13	of	of	ADP
fnp-3050	456	14	ad	ad	NOUN
fnp-3050	456	15	have	have	AUX
fnp-3050	456	16	been	be	AUX
fnp-3050	456	17	critically	critically	ADV
fnp-3050	456	18	reviewed	review	VERB
fnp-3050	456	19	recently	recently	ADV
fnp-3050	456	20	[	[	X
fnp-3050	456	21	174	174	NUM
fnp-3050	456	22	]	]	PUNCT
fnp-3050	456	23	.	.	PUNCT
fnp-3050	457	1	the	the	DET
fnp-3050	457	2	most	most	ADV
fnp-3050	457	3	frequent	frequent	ADJ
fnp-3050	457	4	co	co	NOUN
fnp-3050	457	5	-	-	NOUN
fnp-3050	457	6	pathologies	pathology	NOUN
fnp-3050	457	7	are	be	AUX
fnp-3050	457	8	cerebrovascular	cerebrovascular	ADJ
fnp-3050	457	9	disease	disease	NOUN
fnp-3050	457	10	(	(	PUNCT
fnp-3050	457	11	cvd	cvd	PROPN
fnp-3050	457	12	)	)	PUNCT
fnp-3050	457	13	and	and	CCONJ
fnp-3050	457	14	lewy	lewy	PROPN
fnp-3050	457	15	and	and	CCONJ
fnp-3050	457	16	tdp-43	tdp-43	PROPN
fnp-3050	457	17	proteinopathies	proteinopathie	NOUN
fnp-3050	457	18	[	[	X
fnp-3050	457	19	31	31	NUM
fnp-3050	457	20	,	,	PUNCT
fnp-3050	457	21	258	258	NUM
fnp-3050	457	22	,	,	PUNCT
fnp-3050	457	23	299	299	NUM
fnp-3050	457	24	,	,	PUNCT
fnp-3050	457	25	300	300	NUM
fnp-3050	457	26	]	]	PUNCT
fnp-3050	457	27	.	.	PUNCT
fnp-3050	458	1	in	in	ADP
fnp-3050	458	2	a	a	DET
fnp-3050	458	3	consecutive	consecutive	ADJ
fnp-3050	458	4	autopsy	autopsy	ADJ
fnp-3050	458	5	series	series	NOUN
fnp-3050	458	6	of	of	ADP
fnp-3050	458	7	2,060	2,060	NUM
fnp-3050	458	8	elderly	elderly	ADJ
fnp-3050	458	9	demented	demented	ADJ
fnp-3050	458	10	patients	patient	NOUN
fnp-3050	458	11	and	and	CCONJ
fnp-3050	458	12	those	those	PRON
fnp-3050	458	13	with	with	ADP
fnp-3050	458	14	the	the	DET
fnp-3050	458	15	clinical	clinical	ADJ
fnp-3050	458	16	diagnosis	diagnosis	NOUN
fnp-3050	458	17	of	of	ADP
fnp-3050	458	18	ad	ad	NOUN
fnp-3050	458	19	,	,	PUNCT
fnp-3050	458	20	adnc	adnc	ADJ
fnp-3050	458	21	were	be	AUX
fnp-3050	458	22	present	present	ADJ
fnp-3050	458	23	in	in	ADP
fnp-3050	458	24	82.9	82.9	NUM
fnp-3050	458	25	%	%	NOUN
fnp-3050	458	26	of	of	ADP
fnp-3050	458	27	all	all	PRON
fnp-3050	458	28	demented	demented	ADJ
fnp-3050	458	29	and	and	CCONJ
fnp-3050	458	30	in	in	ADP
fnp-3050	458	31	92.8	92.8	NUM
fnp-3050	458	32	%	%	NOUN
fnp-3050	458	33	of	of	ADP
fnp-3050	458	34	clinically	clinically	ADV
fnp-3050	458	35	diagnosed	diagnose	VERB
fnp-3050	458	36	ad	ad	NOUN
fnp-3050	458	37	cases	case	NOUN
fnp-3050	458	38	,	,	PUNCT
fnp-3050	458	39	but	but	CCONJ
fnp-3050	458	40	only	only	ADV
fnp-3050	458	41	33.6	33.6	NUM
fnp-3050	458	42	%	%	NOUN
fnp-3050	458	43	and	and	CCONJ
fnp-3050	458	44	47.6	47.6	NUM
fnp-3050	458	45	%	%	NOUN
fnp-3050	458	46	,	,	PUNCT
fnp-3050	458	47	respectively	respectively	ADV
fnp-3050	458	48	,	,	PUNCT
fnp-3050	458	49	showed	show	VERB
fnp-3050	458	50	pure	pure	ADJ
fnp-3050	458	51	adnc	adnc	NOUN
fnp-3050	458	52	(	(	PUNCT
fnp-3050	458	53	abc	abc	PROPN
fnp-3050	458	54	3/3/3	3/3/3	NUM
fnp-3050	458	55	)	)	PUNCT
fnp-3050	458	56	.	.	PUNCT
fnp-3050	459	1	the	the	DET
fnp-3050	459	2	others	other	NOUN
fnp-3050	459	3	were	be	AUX
fnp-3050	459	4	either	either	CCONJ
fnp-3050	459	5	atypical	atypical	ADJ
fnp-3050	459	6	ad	ad	NOUN
fnp-3050	459	7	forms	form	NOUN
fnp-3050	459	8	or	or	CCONJ
fnp-3050	459	9	subtypes	subtype	NOUN
fnp-3050	459	10	(	(	PUNCT
fnp-3050	459	11	including	include	VERB
fnp-3050	459	12	part	part	NOUN
fnp-3050	459	13	)	)	PUNCT
fnp-3050	459	14	(	(	PUNCT
fnp-3050	459	15	7	7	NUM
fnp-3050	459	16	and	and	CCONJ
fnp-3050	459	17	6	6	NUM
fnp-3050	459	18	%	%	NOUN
fnp-3050	459	19	,	,	PUNCT
fnp-3050	459	20	respectively	respectively	ADV
fnp-3050	459	21	)	)	PUNCT
fnp-3050	459	22	or	or	CCONJ
fnp-3050	459	23	exhibited	exhibit	VERB
fnp-3050	459	24	additional	additional	ADJ
fnp-3050	459	25	cvd	cvd	NOUN
fnp-3050	459	26	(	(	PUNCT
fnp-3050	459	27	24.3	24.3	NUM
fnp-3050	459	28	%	%	NOUN
fnp-3050	459	29	)	)	PUNCT
fnp-3050	459	30	,	,	PUNCT
fnp-3050	459	31	lewy	lewy	PROPN
fnp-3050	459	32	(	(	PUNCT
fnp-3050	459	33	12.5	12.5	NUM
fnp-3050	459	34	%	%	NOUN
fnp-3050	459	35	)	)	PUNCT
fnp-3050	459	36	or	or	CCONJ
fnp-3050	459	37	other	other	ADJ
fnp-3050	459	38	mixed	mixed	ADJ
fnp-3050	459	39	pathologies	pathology	NOUN
fnp-3050	459	40	.	.	PUNCT
fnp-3050	460	1	vascular	vascular	ADJ
fnp-3050	460	2	dementia	dementia	NOUN
fnp-3050	460	3	in	in	ADP
fnp-3050	460	4	this	this	DET
fnp-3050	460	5	cohort	cohort	NOUN
fnp-3050	460	6	accounted	account	VERB
fnp-3050	460	7	for	for	ADP
fnp-3050	460	8	only	only	ADV
fnp-3050	460	9	12.2	12.2	NUM
fnp-3050	460	10	%	%	NOUN
fnp-3050	460	11	and	and	CCONJ
fnp-3050	460	12	3.3	3.3	NUM
fnp-3050	460	13	%	%	NOUN
fnp-3050	460	14	,	,	PUNCT
fnp-3050	460	15	respectively	respectively	ADV
fnp-3050	460	16	;	;	PUNCT
fnp-3050	460	17	other	other	ADJ
fnp-3050	460	18	non	non	ADJ
fnp-3050	460	19	-	-	ADJ
fnp-3050	460	20	ad	ad	ADJ
fnp-3050	460	21	pathologies	pathology	NOUN
fnp-3050	460	22	were	be	AUX
fnp-3050	460	23	present	present	ADJ
fnp-3050	460	24	in	in	ADP
fnp-3050	460	25	7.2	7.2	NUM
fnp-3050	460	26	%	%	NOUN
fnp-3050	460	27	and	and	CCONJ
fnp-3050	460	28	3.7	3.7	NUM
fnp-3050	460	29	%	%	NOUN
fnp-3050	460	30	[	[	X
fnp-3050	460	31	301	301	NUM
fnp-3050	460	32	]	]	PUNCT
fnp-3050	460	33	.	.	PUNCT
fnp-3050	461	1	another	another	DET
fnp-3050	461	2	study	study	NOUN
fnp-3050	461	3	of	of	ADP
fnp-3050	461	4	demented	demented	ADJ
fnp-3050	461	5	elderly	elderly	ADJ
fnp-3050	461	6	persons	person	NOUN
fnp-3050	461	7	reported	report	VERB
fnp-3050	461	8	pure	pure	ADJ
fnp-3050	461	9	adnc	adnc	NOUN
fnp-3050	461	10	in	in	ADP
fnp-3050	461	11	only	only	ADV
fnp-3050	461	12	31	31	NUM
fnp-3050	461	13	%	%	NOUN
fnp-3050	461	14	and	and	CCONJ
fnp-3050	461	15	multiple	multiple	ADJ
fnp-3050	461	16	pathologies	pathology	NOUN
fnp-3050	461	17	in	in	ADP
fnp-3050	461	18	63	63	NUM
fnp-3050	461	19	%	%	NOUN
fnp-3050	461	20	[	[	X
fnp-3050	461	21	302	302	NUM
fnp-3050	461	22	]	]	PUNCT
fnp-3050	461	23	.	.	PUNCT
fnp-3050	462	1	a	a	DET
fnp-3050	462	2	review	review	NOUN
fnp-3050	462	3	of	of	ADP
fnp-3050	462	4	12	12	NUM
fnp-3050	462	5	studies	study	NOUN
fnp-3050	462	6	with	with	ADP
fnp-3050	462	7	3,574	3,574	NUM
fnp-3050	462	8	patients	patient	NOUN
fnp-3050	462	9	,	,	PUNCT
fnp-3050	462	10	irrespective	irrespective	ADV
fnp-3050	462	11	of	of	ADP
fnp-3050	462	12	the	the	DET
fnp-3050	462	13	clinical	clinical	ADJ
fnp-3050	462	14	symptoms	symptom	NOUN
fnp-3050	462	15	,	,	PUNCT
fnp-3050	462	16	reported	report	VERB
fnp-3050	462	17	adnc	adnc	ADV
fnp-3050	462	18	between	between	ADP
fnp-3050	462	19	19	19	NUM
fnp-3050	462	20	%	%	NOUN
fnp-3050	462	21	and	and	CCONJ
fnp-3050	462	22	67	67	NUM
fnp-3050	462	23	%	%	NOUN
fnp-3050	462	24	,	,	PUNCT
fnp-3050	462	25	lewy	lewy	PROPN
fnp-3050	462	26	pathologies	pathology	NOUN
fnp-3050	462	27	in	in	ADP
fnp-3050	462	28	6	6	NUM
fnp-3050	462	29	%	%	NOUN
fnp-3050	462	30	to	to	PART
fnp-3050	462	31	39	39	NUM
fnp-3050	462	32	%	%	NOUN
fnp-3050	462	33	,	,	PUNCT
fnp-3050	462	34	vascular	vascular	ADJ
fnp-3050	462	35	pathologies	pathology	NOUN
fnp-3050	462	36	in	in	ADP
fnp-3050	462	37	28	28	NUM
fnp-3050	462	38	%	%	NOUN
fnp-3050	462	39	and	and	CCONJ
fnp-3050	462	40	70	70	NUM
fnp-3050	462	41	%	%	NOUN
fnp-3050	462	42	,	,	PUNCT
fnp-3050	462	43	tdp-43	tdp-43	NOUN
fnp-3050	462	44	proteinopathy	proteinopathy	ADJ
fnp-3050	462	45	in	in	ADP
fnp-3050	462	46	19	19	NUM
fnp-3050	462	47	%	%	NOUN
fnp-3050	462	48	to	to	PART
fnp-3050	462	49	78	78	NUM
fnp-3050	462	50	%	%	NOUN
fnp-3050	463	1	[	[	X
fnp-3050	463	2	290	290	NUM
fnp-3050	463	3	]	]	PUNCT
fnp-3050	463	4	,	,	PUNCT
fnp-3050	463	5	hippocampal	hippocampal	ADJ
fnp-3050	463	6	sclerosis	sclerosis	NOUN
fnp-3050	463	7	between	between	ADP
fnp-3050	463	8	3	3	NUM
fnp-3050	463	9	%	%	NOUN
fnp-3050	463	10	and	and	CCONJ
fnp-3050	463	11	13	13	NUM
fnp-3050	463	12	%	%	NOUN
fnp-3050	463	13	,	,	PUNCT
fnp-3050	463	14	and	and	CCONJ
fnp-3050	463	15	mixed	mixed	ADJ
fnp-3050	463	16	pathologies	pathology	NOUN
fnp-3050	463	17	between	between	ADP
fnp-3050	463	18	8	8	NUM
fnp-3050	463	19	%	%	NOUN
fnp-3050	463	20	and	and	CCONJ
fnp-3050	463	21	70	70	NUM
fnp-3050	463	22	%	%	NOUN
fnp-3050	463	23	[	[	X
fnp-3050	463	24	295	295	NUM
fnp-3050	463	25	]	]	PUNCT
fnp-3050	463	26	.	.	PUNCT
fnp-3050	464	1	among	among	ADP
fnp-3050	464	2	447	447	NUM
fnp-3050	464	3	patients	patient	NOUN
fnp-3050	464	4	with	with	ADP
fnp-3050	464	5	probable	probable	ADJ
fnp-3050	464	6	ad	ad	NOUN
fnp-3050	464	7	,	,	PUNCT
fnp-3050	464	8	only	only	ADV
fnp-3050	464	9	3.13	3.13	NUM
fnp-3050	464	10	%	%	NOUN
fnp-3050	464	11	showed	show	VERB
fnp-3050	464	12	pure	pure	ADJ
fnp-3050	464	13	adnc	adnc	ADJ
fnp-3050	464	14	,	,	PUNCT
fnp-3050	464	15	27.3	27.3	NUM
fnp-3050	464	16	%	%	NOUN
fnp-3050	464	17	ad+cvd	ad+cvd	NOUN
fnp-3050	465	1	+	+	CCONJ
fnp-3050	465	2	other	other	ADJ
fnp-3050	465	3	,	,	PUNCT
fnp-3050	465	4	3	3	NUM
fnp-3050	465	5	%	%	NOUN
fnp-3050	465	6	ad	ad	NOUN
fnp-3050	465	7	+	+	X
fnp-3050	465	8	cvd	cvd	PROPN
fnp-3050	465	9	,	,	PUNCT
fnp-3050	465	10	7.6	7.6	NUM
fnp-3050	465	11	%	%	NOUN
fnp-3050	465	12	ad	ad	NOUN
fnp-3050	465	13	+	+	CCONJ
fnp-3050	465	14	other	other	ADJ
fnp-3050	465	15	degenerative	degenerative	ADJ
fnp-3050	465	16	lesions	lesion	NOUN
fnp-3050	465	17	,	,	PUNCT
fnp-3050	465	18	and	and	CCONJ
fnp-3050	465	19	47	47	NUM
fnp-3050	465	20	%	%	NOUN
fnp-3050	465	21	ad+cvd	ad+cvd	NOUN
fnp-3050	466	1	+	+	CCONJ
fnp-3050	466	2	other	other	ADJ
fnp-3050	466	3	neurodegenerative	neurodegenerative	ADJ
fnp-3050	466	4	lesions	lesion	NOUN
fnp-3050	466	5	[	[	X
fnp-3050	466	6	293	293	NUM
fnp-3050	466	7	]	]	PUNCT
fnp-3050	466	8	.	.	PUNCT
fnp-3050	467	1	this	this	DET
fnp-3050	467	2	list	list	NOUN
fnp-3050	467	3	of	of	ADP
fnp-3050	467	4	combinations	combination	NOUN
fnp-3050	467	5	is	be	AUX
fnp-3050	467	6	not	not	PART
fnp-3050	467	7	complete	complete	ADJ
fnp-3050	467	8	and	and	CCONJ
fnp-3050	467	9	there	there	PRON
fnp-3050	467	10	are	be	VERB
fnp-3050	467	11	other	other	ADJ
fnp-3050	467	12	combinations	combination	NOUN
fnp-3050	467	13	with	with	ADP
fnp-3050	467	14	rare	rare	ADJ
fnp-3050	467	15	entities	entity	NOUN
fnp-3050	467	16	that	that	PRON
fnp-3050	467	17	need	need	VERB
fnp-3050	467	18	specific	specific	ADJ
fnp-3050	467	19	attention	attention	NOUN
fnp-3050	468	1	[	[	X
fnp-3050	468	2	174	174	NUM
fnp-3050	468	3	]	]	PUNCT
fnp-3050	468	4	.	.	PUNCT
fnp-3050	469	1	among	among	ADP
fnp-3050	469	2	673	673	NUM
fnp-3050	469	3	autopsy	autopsy	ADJ
fnp-3050	469	4	cases	case	NOUN
fnp-3050	469	5	,	,	PUNCT
fnp-3050	469	6	including	include	VERB
fnp-3050	469	7	320	320	NUM
fnp-3050	469	8	demented	demented	ADJ
fnp-3050	469	9	,	,	PUNCT
fnp-3050	469	10	the	the	DET
fnp-3050	469	11	majority	majority	NOUN
fnp-3050	469	12	showed	show	VERB
fnp-3050	469	13	mixed	mixed	ADJ
fnp-3050	469	14	pathologies	pathology	NOUN
fnp-3050	469	15	[	[	X
fnp-3050	469	16	274	274	NUM
fnp-3050	469	17	]	]	PUNCT
fnp-3050	469	18	.	.	PUNCT
fnp-3050	470	1	late	late	PROPN
fnp-3050	470	2	-	-	PUNCT
fnp-3050	470	3	nc	nc	PROPN
fnp-3050	470	4	was	be	AUX
fnp-3050	470	5	present	present	ADJ
fnp-3050	470	6	in	in	ADP
fnp-3050	470	7	57	57	NUM
fnp-3050	470	8	%	%	NOUN
fnp-3050	470	9	of	of	ADP
fnp-3050	470	10	ad	ad	NOUN
fnp-3050	470	11	cases	case	NOUN
fnp-3050	470	12	and	and	CCONJ
fnp-3050	470	13	was	be	AUX
fnp-3050	470	14	associated	associate	VERB
fnp-3050	470	15	with	with	ADP
fnp-3050	470	16	more	more	ADV
fnp-3050	470	17	rapid	rapid	ADJ
fnp-3050	470	18	disease	disease	NOUN
fnp-3050	470	19	progression	progression	NOUN
fnp-3050	471	1	[	[	X
fnp-3050	471	2	259	259	NUM
fnp-3050	471	3	]	]	PUNCT
fnp-3050	471	4	.	.	PUNCT
fnp-3050	472	1	increased	increase	VERB
fnp-3050	472	2	tdp-43	tdp-43	PROPN
fnp-3050	472	3	pathology	pathology	NOUN
fnp-3050	472	4	in	in	ADP
fnp-3050	472	5	typical	typical	ADJ
fnp-3050	472	6	ad	ad	NOUN
fnp-3050	472	7	and	and	CCONJ
fnp-3050	473	1	lp	lp	NOUN
fnp-3050	473	2	-	-	NOUN
fnp-3050	473	3	ad	ad	NOUN
fnp-3050	473	4	compared	compare	VERB
fnp-3050	473	5	to	to	ADP
fnp-3050	473	6	hcsp	hcsp	NOUN
fnp-3050	473	7	-	-	PUNCT
fnp-3050	473	8	ad	ad	NOUN
fnp-3050	473	9	[	[	X
fnp-3050	473	10	262	262	NUM
fnp-3050	473	11	]	]	PUNCT
fnp-3050	473	12	was	be	AUX
fnp-3050	473	13	due	due	ADJ
fnp-3050	473	14	to	to	ADP
fnp-3050	473	15	a	a	DET
fnp-3050	473	16	strong	strong	ADJ
fnp-3050	473	17	association	association	NOUN
fnp-3050	473	18	between	between	ADP
fnp-3050	473	19	hippocampal	hippocampal	ADJ
fnp-3050	473	20	sclerosis	sclerosis	NOUN
fnp-3050	473	21	and	and	CCONJ
fnp-3050	473	22	tdp-43	tdp-43	PROPN
fnp-3050	473	23	,	,	PUNCT
fnp-3050	473	24	but	but	CCONJ
fnp-3050	473	25	clinical	clinical	ADJ
fnp-3050	473	26	presentation	presentation	NOUN
fnp-3050	473	27	seemed	seem	VERB
fnp-3050	473	28	to	to	PART
fnp-3050	473	29	be	be	AUX
fnp-3050	473	30	driven	drive	VERB
fnp-3050	473	31	by	by	ADP
fnp-3050	473	32	morphological	morphological	ADJ
fnp-3050	473	33	subtypes	subtype	NOUN
fnp-3050	473	34	and	and	CCONJ
fnp-3050	473	35	not	not	PART
fnp-3050	473	36	by	by	ADP
fnp-3050	473	37	tdp-43	tdp-43	PROPN
fnp-3050	473	38	pathology	pathology	NOUN
fnp-3050	474	1	[	[	X
fnp-3050	474	2	290	290	NUM
fnp-3050	474	3	]	]	PUNCT
fnp-3050	474	4	.	.	PUNCT
fnp-3050	475	1	among	among	ADP
fnp-3050	475	2	61	61	NUM
fnp-3050	475	3	autopsy	autopsy	ADJ
fnp-3050	475	4	-	-	PUNCT
fnp-3050	475	5	proven	prove	VERB
fnp-3050	475	6	ad	ad	NOUN
fnp-3050	475	7	cases	case	NOUN
fnp-3050	475	8	,	,	PUNCT
fnp-3050	475	9	late	late	PROPN
fnp-3050	475	10	-	-	PUNCT
fnp-3050	475	11	nc	nc	PROPN
fnp-3050	475	12	was	be	AUX
fnp-3050	475	13	present	present	ADJ
fnp-3050	475	14	in	in	ADP
fnp-3050	475	15	67.2	67.2	NUM
fnp-3050	475	16	%	%	NOUN
fnp-3050	475	17	(	(	PUNCT
fnp-3050	475	18	ad	ad	NOUN
fnp-3050	475	19	,	,	PUNCT
fnp-3050	475	20	late	late	PROPN
fnp-3050	475	21	-	-	PUNCT
fnp-3050	475	22	nc	nc	PROPN
fnp-3050	475	23	)	)	PUNCT
fnp-3050	475	24	,	,	PUNCT
fnp-3050	475	25	however	however	ADV
fnp-3050	475	26	,	,	PUNCT
fnp-3050	475	27	it	it	PRON
fnp-3050	475	28	was	be	AUX
fnp-3050	475	29	not	not	PART
fnp-3050	475	30	associated	associate	VERB
fnp-3050	475	31	with	with	ADP
fnp-3050	475	32	an	an	DET
fnp-3050	475	33	increase	increase	NOUN
fnp-3050	475	34	of	of	ADP
fnp-3050	475	35	the	the	DET
fnp-3050	475	36	burden	burden	NOUN
fnp-3050	475	37	of	of	ADP
fnp-3050	475	38	early	early	ADJ
fnp-3050	475	39	or	or	CCONJ
fnp-3050	475	40	late	late	ADJ
fnp-3050	475	41	tau	tau	PROPN
fnp-3050	475	42	nor	nor	CCONJ
fnp-3050	475	43	aβ	aβ	DET
fnp-3050	475	44	pathology	pathology	NOUN
fnp-3050	475	45	.	.	PUNCT
fnp-3050	476	1	late	late	PROPN
fnp-3050	476	2	-	-	PUNCT
fnp-3050	476	3	nc	nc	PROPN
fnp-3050	476	4	showed	show	VERB
fnp-3050	476	5	a	a	DET
fnp-3050	476	6	lower	low	ADJ
fnp-3050	476	7	final	final	ADJ
fnp-3050	476	8	mini	mini	ADJ
fnp-3050	476	9	mental	mental	ADJ
fnp-3050	476	10	state	state	NOUN
fnp-3050	476	11	examination	examination	NOUN
fnp-3050	476	12	(	(	PUNCT
fnp-3050	476	13	mmse	mmse	ADJ
fnp-3050	476	14	)	)	PUNCT
fnp-3050	476	15	score	score	NOUN
fnp-3050	476	16	independent	independent	ADJ
fnp-3050	476	17	of	of	ADP
fnp-3050	476	18	tau	tau	PROPN
fnp-3050	476	19	pathology	pathology	NOUN
fnp-3050	476	20	[	[	X
fnp-3050	476	21	303	303	NUM
fnp-3050	476	22	]	]	PUNCT
fnp-3050	476	23	.	.	PUNCT
fnp-3050	477	1	among	among	ADP
fnp-3050	477	2	172	172	NUM
fnp-3050	477	3	autopsy	autopsy	ADJ
fnp-3050	477	4	-	-	PUNCT
fnp-3050	477	5	confirmed	confirm	VERB
fnp-3050	477	6	ad	ad	NOUN
fnp-3050	477	7	cases	case	NOUN
fnp-3050	477	8	,	,	PUNCT
fnp-3050	477	9	19	19	NUM
fnp-3050	477	10	%	%	NOUN
fnp-3050	477	11	were	be	AUX
fnp-3050	477	12	classified	classify	VERB
fnp-3050	477	13	as	as	ADP
fnp-3050	477	14	non	non	ADJ
fnp-3050	477	15	-	-	ADJ
fnp-3050	477	16	amnestic	amnestic	ADJ
fnp-3050	477	17	,	,	PUNCT
fnp-3050	477	18	69	69	NUM
fnp-3050	477	19	%	%	NOUN
fnp-3050	477	20	of	of	ADP
fnp-3050	477	21	which	which	PRON
fnp-3050	477	22	had	have	VERB
fnp-3050	477	23	typical	typical	ADJ
fnp-3050	477	24	adnc	adnc	ADJ
fnp-3050	477	25	,	,	PUNCT
fnp-3050	477	26	31	31	NUM
fnp-3050	477	27	%	%	NOUN
fnp-3050	477	28	were	be	AUX
fnp-3050	477	29	hcsp	hcsp	NOUN
fnp-3050	477	30	-	-	PUNCT
fnp-3050	477	31	ad	ad	NOUN
fnp-3050	477	32	,	,	PUNCT
fnp-3050	477	33	36	36	NUM
fnp-3050	477	34	%	%	NOUN
fnp-3050	477	35	tdp-43	tdp-43	NOUN
fnp-3050	477	36	-	-	PUNCT
fnp-3050	477	37	positive	positive	ADJ
fnp-3050	477	38	,	,	PUNCT
fnp-3050	477	39	while	while	SCONJ
fnp-3050	477	40	there	there	PRON
fnp-3050	477	41	were	be	VERB
fnp-3050	477	42	no	no	DET
fnp-3050	477	43	lp	lp	ADJ
fnp-3050	477	44	-	-	PUNCT
fnp-3050	477	45	ad	ad	NOUN
fnp-3050	477	46	cases	case	NOUN
fnp-3050	477	47	[	[	X
fnp-3050	477	48	287	287	NUM
fnp-3050	477	49	]	]	PUNCT
fnp-3050	477	50	.	.	PUNCT
fnp-3050	478	1	in	in	ADP
fnp-3050	478	2	a	a	DET
fnp-3050	478	3	recent	recent	ADJ
fnp-3050	478	4	study	study	NOUN
fnp-3050	478	5	of	of	ADP
fnp-3050	478	6	46	46	NUM
fnp-3050	478	7	autopsy	autopsy	ADJ
fnp-3050	478	8	-	-	PUNCT
fnp-3050	478	9	confirmed	confirm	VERB
fnp-3050	478	10	ad	ad	NOUN
fnp-3050	478	11	cases	case	NOUN
fnp-3050	478	12	,	,	PUNCT
fnp-3050	478	13	63	63	NUM
fnp-3050	478	14	%	%	NOUN
fnp-3050	478	15	exhibited	exhibit	VERB
fnp-3050	478	16	late	late	ADJ
fnp-3050	478	17	-	-	PUNCT
fnp-3050	478	18	nc	nc	PROPN
fnp-3050	478	19	(	(	PUNCT
fnp-3050	478	20	ad+	ad+	PROPN
fnp-3050	478	21	)	)	PUNCT
fnp-3050	478	22	and	and	CCONJ
fnp-3050	478	23	a	a	DET
fnp-3050	478	24	higher	high	ADJ
fnp-3050	478	25	burden	burden	NOUN
fnp-3050	478	26	of	of	ADP
fnp-3050	478	27	hp	hp	NOUN
fnp-3050	478	28	-	-	NOUN
fnp-3050	478	29	tau	tau	NOUN
fnp-3050	478	30	.	.	PUNCT
fnp-3050	479	1	this	this	PRON
fnp-3050	479	2	indicates	indicate	VERB
fnp-3050	479	3	a	a	DET
fnp-3050	479	4	possible	possible	ADJ
fnp-3050	479	5	progression	progression	NOUN
fnp-3050	479	6	of	of	ADP
fnp-3050	479	7	the	the	DET
fnp-3050	479	8	disease	disease	NOUN
fnp-3050	479	9	,	,	PUNCT
fnp-3050	479	10	whereas	whereas	SCONJ
fnp-3050	479	11	ad	ad	NOUN
fnp-3050	479	12	plus	plus	CCONJ
fnp-3050	479	13	late	late	PROPN
fnp-3050	479	14	-	-	PUNCT
fnp-3050	479	15	nc	nc	PROPN
fnp-3050	479	16	was	be	AUX
fnp-3050	479	17	not	not	PART
fnp-3050	479	18	associated	associate	VERB
fnp-3050	479	19	with	with	ADP
fnp-3050	479	20	differences	difference	NOUN
fnp-3050	479	21	in	in	ADP
fnp-3050	479	22	cognitive	cognitive	ADJ
fnp-3050	479	23	scores	score	NOUN
fnp-3050	479	24	[	[	X
fnp-3050	479	25	304	304	NUM
fnp-3050	479	26	]	]	PUNCT
fnp-3050	479	27	.	.	PUNCT
fnp-3050	480	1	late	late	PROPN
fnp-3050	480	2	-	-	PUNCT
fnp-3050	480	3	nc	nc	PROPN
fnp-3050	480	4	may	may	AUX
fnp-3050	480	5	also	also	ADV
fnp-3050	480	6	occur	occur	VERB
fnp-3050	480	7	in	in	ADP
fnp-3050	480	8	isolation	isolation	NOUN
fnp-3050	480	9	and	and	CCONJ
fnp-3050	480	10	has	have	AUX
fnp-3050	480	11	been	be	AUX
fnp-3050	480	12	viewed	view	VERB
fnp-3050	480	13	as	as	ADP
fnp-3050	480	14	a	a	DET
fnp-3050	480	15	common	common	ADJ
fnp-3050	480	16	brain	brain	NOUN
fnp-3050	480	17	disease	disease	NOUN
fnp-3050	480	18	in	in	ADP
fnp-3050	480	19	aging	age	VERB
fnp-3050	480	20	[	[	X
fnp-3050	480	21	258	258	NUM
fnp-3050	480	22	]	]	PUNCT
fnp-3050	480	23	.	.	PUNCT
fnp-3050	481	1	among	among	ADP
fnp-3050	481	2	574	574	NUM
fnp-3050	481	3	individuals	individual	NOUN
fnp-3050	481	4	with	with	ADP
fnp-3050	481	5	complete	complete	ADJ
fnp-3050	481	6	measurements	measurement	NOUN
fnp-3050	481	7	of	of	ADP
fnp-3050	481	8	mmse	mmse	NOUN
fnp-3050	481	9	and	and	CCONJ
fnp-3050	481	10	the	the	DET
fnp-3050	481	11	clinical	clinical	ADJ
fnp-3050	481	12	dementia	dementia	NOUN
fnp-3050	481	13	rating	rating	NOUN
fnp-3050	481	14	scale	scale	NOUN
fnp-3050	481	15	sum	sum	NOUN
fnp-3050	481	16	of	of	ADP
fnp-3050	481	17	boxes	box	NOUN
fnp-3050	481	18	(	(	PUNCT
fnp-3050	481	19	cdr	cdr	NOUN
fnp-3050	481	20	-	-	PUNCT
fnp-3050	481	21	sb	sb	NOUN
fnp-3050	481	22	)	)	PUNCT
fnp-3050	481	23	from	from	ADP
fnp-3050	481	24	39	39	NUM
fnp-3050	481	25	ad	ad	NOUN
fnp-3050	481	26	centers	center	NOUN
fnp-3050	481	27	across	across	ADP
fnp-3050	481	28	the	the	DET
fnp-3050	481	29	usa	usa	PROPN
fnp-3050	481	30	,	,	PUNCT
fnp-3050	481	31	63	63	NUM
fnp-3050	481	32	%	%	NOUN
fnp-3050	481	33	of	of	ADP
fnp-3050	481	34	those	those	PRON
fnp-3050	481	35	given	give	VERB
fnp-3050	481	36	the	the	DET
fnp-3050	481	37	'	'	PUNCT
fnp-3050	481	38	gold	gold	ADJ
fnp-3050	481	39	standard	standard	NOUN
fnp-3050	481	40	'	'	PART
fnp-3050	481	41	diagnosis	diagnosis	NOUN
fnp-3050	481	42	of	of	ADP
fnp-3050	481	43	ad	ad	NOUN
fnp-3050	481	44	,	,	PUNCT
fnp-3050	481	45	possessed	possess	VERB
fnp-3050	481	46	either	either	CCONJ
fnp-3050	481	47	tdp-43	tdp-43	ADV
fnp-3050	481	48	proteinopathy	proteinopathy	ADJ
fnp-3050	481	49	or	or	CCONJ
fnp-3050	481	50	caa	caa	NOUN
fnp-3050	481	51	of	of	ADP
fnp-3050	481	52	sufficient	sufficient	ADJ
fnp-3050	481	53	severity	severity	NOUN
fnp-3050	481	54	to	to	PART
fnp-3050	481	55	independently	independently	ADV
fnp-3050	481	56	explain	explain	VERB
fnp-3050	481	57	the	the	DET
fnp-3050	481	58	majority	majority	NOUN
fnp-3050	481	59	of	of	ADP
fnp-3050	481	60	their	their	PRON
fnp-3050	481	61	cognitive	cognitive	ADJ
fnp-3050	481	62	impairment	impairment	NOUN
fnp-3050	481	63	.	.	PUNCT
fnp-3050	482	1	aβ	aβ	PRON
fnp-3050	482	2	and/or	and/or	CCONJ
fnp-3050	482	3	tau	tau	PROPN
fnp-3050	482	4	burden	burden	NOUN
fnp-3050	482	5	,	,	PUNCT
fnp-3050	482	6	particularly	particularly	ADV
fnp-3050	482	7	in	in	ADP
fnp-3050	482	8	braak	braak	NOUN
fnp-3050	482	9	stages	stage	NOUN
fnp-3050	482	10	iv	iv	ADP
fnp-3050	482	11	to	to	ADP
fnp-3050	482	12	vi	vi	NUM
fnp-3050	482	13	,	,	PUNCT
fnp-3050	482	14	and	and	CCONJ
fnp-3050	482	15	small	small	ADJ
fnp-3050	482	16	cerebral	cerebral	ADJ
fnp-3050	482	17	vessel	vessel	NOUN
fnp-3050	482	18	disease	disease	NOUN
fnp-3050	482	19	may	may	AUX
fnp-3050	482	20	synergistically	synergistically	ADV
fnp-3050	482	21	affect	affect	VERB
fnp-3050	482	22	cognitive	cognitive	ADJ
fnp-3050	482	23	decline	decline	NOUN
fnp-3050	483	1	[	[	X
fnp-3050	483	2	305	305	NUM
fnp-3050	483	3	]	]	PUNCT
fnp-3050	483	4	,	,	PUNCT
fnp-3050	483	5	and	and	CCONJ
fnp-3050	483	6	a	a	DET
fnp-3050	483	7	significant	significant	ADJ
fnp-3050	483	8	interaction	interaction	NOUN
fnp-3050	483	9	was	be	AUX
fnp-3050	483	10	found	find	VERB
fnp-3050	483	11	between	between	ADP
fnp-3050	483	12	braak	braak	PROPN
fnp-3050	483	13	nft	nft	PROPN
fnp-3050	483	14	stages	stage	NOUN
fnp-3050	483	15	,	,	PUNCT
fnp-3050	483	16	caa	caa	NOUN
fnp-3050	483	17	status	status	NOUN
fnp-3050	483	18	and	and	CCONJ
fnp-3050	483	19	cognitive	cognitive	ADJ
fnp-3050	483	20	decline	decline	NOUN
fnp-3050	483	21	,	,	PUNCT
fnp-3050	483	22	suggesting	suggest	VERB
fnp-3050	483	23	that	that	SCONJ
fnp-3050	483	24	there	there	PRON
fnp-3050	483	25	is	be	VERB
fnp-3050	483	26	a	a	DET
fnp-3050	483	27	significant	significant	ADJ
fnp-3050	483	28	interaction	interaction	NOUN
fnp-3050	483	29	between	between	ADP
fnp-3050	483	30	tau	tau	PROPN
fnp-3050	483	31	pathology	pathology	NOUN
fnp-3050	483	32	and	and	CCONJ
fnp-3050	483	33	caa	caa	NOUN
fnp-3050	483	34	on	on	ADP
fnp-3050	483	35	cognition	cognition	NOUN
fnp-3050	483	36	within	within	ADP
fnp-3050	483	37	the	the	DET
fnp-3050	483	38	ad	ad	NOUN
fnp-3050	483	39	clinical	clinical	ADJ
fnp-3050	483	40	spectrum	spectrum	NOUN
fnp-3050	483	41	[	[	X
fnp-3050	483	42	306	306	NUM
fnp-3050	483	43	]	]	PUNCT
fnp-3050	483	44	.	.	PUNCT
fnp-3050	484	1	hence	hence	ADV
fnp-3050	484	2	,	,	PUNCT
fnp-3050	484	3	interventions	intervention	NOUN
fnp-3050	484	4	targeting	target	VERB
fnp-3050	484	5	caa	caa	NOUN
fnp-3050	484	6	may	may	AUX
fnp-3050	484	7	contribute	contribute	VERB
fnp-3050	484	8	to	to	PART
fnp-3050	484	9	delay	delay	VERB
fnp-3050	484	10	the	the	DET
fnp-3050	484	11	onset	onset	NOUN
fnp-3050	484	12	of	of	ADP
fnp-3050	484	13	cognitive	cognitive	ADJ
fnp-3050	484	14	impairment	impairment	NOUN
fnp-3050	484	15	,	,	PUNCT
fnp-3050	484	16	particularly	particularly	ADV
fnp-3050	484	17	in	in	ADP
fnp-3050	484	18	individuals	individual	NOUN
fnp-3050	484	19	with	with	ADP
fnp-3050	484	20	intermediate	intermediate	ADJ
fnp-3050	484	21	adnc	adnc	ADJ
fnp-3050	484	22	[	[	X
fnp-3050	484	23	307	307	NUM
fnp-3050	484	24	]	]	PUNCT
fnp-3050	484	25	.	.	PUNCT
fnp-3050	485	1	this	this	PRON
fnp-3050	485	2	suggests	suggest	VERB
fnp-3050	485	3	that	that	SCONJ
fnp-3050	485	4	many	many	ADJ
fnp-3050	485	5	individuals	individual	NOUN
fnp-3050	485	6	diagnosed	diagnose	VERB
fnp-3050	485	7	with	with	ADP
fnp-3050	485	8	ad	ad	NOUN
fnp-3050	485	9	may	may	AUX
fnp-3050	485	10	actually	actually	ADV
fnp-3050	485	11	suffer	suffer	VERB
fnp-3050	485	12	from	from	ADP
fnp-3050	485	13	a	a	DET
fnp-3050	485	14	mixed	mixed	ADJ
fnp-3050	485	15	dementia	dementia	NOUN
fnp-3050	485	16	,	,	PUNCT
fnp-3050	485	17	and	and	CCONJ
fnp-3050	485	18	therapeutic	therapeutic	ADJ
fnp-3050	485	19	targeting	target	VERB
fnp-3050	485	20	ad	ad	NOUN
fnp-3050	485	21	-	-	PUNCT
fnp-3050	485	22	related	relate	VERB
fnp-3050	485	23	processes	process	NOUN
fnp-3050	485	24	only	only	ADV
fnp-3050	485	25	may	may	AUX
fnp-3050	485	26	have	have	VERB
fnp-3050	485	27	limited	limit	VERB
fnp-3050	485	28	efficiency	efficiency	NOUN
fnp-3050	485	29	in	in	ADP
fnp-3050	485	30	these	these	DET
fnp-3050	485	31	co	co	ADJ
fnp-3050	485	32	-	-	ADJ
fnp-3050	485	33	morbid	morbid	ADJ
fnp-3050	485	34	populations	population	NOUN
fnp-3050	485	35	[	[	X
fnp-3050	485	36	298	298	NUM
fnp-3050	485	37	]	]	PUNCT
fnp-3050	485	38	.	.	PUNCT
fnp-3050	486	1	based	base	VERB
fnp-3050	486	2	on	on	ADP
fnp-3050	486	3	data	datum	NOUN
fnp-3050	486	4	from	from	ADP
fnp-3050	486	5	the	the	DET
fnp-3050	486	6	nacc	nacc	NOUN
fnp-3050	486	7	,	,	PUNCT
fnp-3050	486	8	1,854	1,854	NUM
fnp-3050	486	9	participants	participant	NOUN
fnp-3050	486	10	with	with	ADP
fnp-3050	486	11	a	a	DET
fnp-3050	486	12	clinical	clinical	ADJ
fnp-3050	486	13	diagnosis	diagnosis	NOUN
fnp-3050	486	14	of	of	ADP
fnp-3050	486	15	ad	ad	NOUN
fnp-3050	486	16	and	and	CCONJ
fnp-3050	486	17	adnc	adnc	ADJ
fnp-3050	486	18	at	at	ADP
fnp-3050	486	19	autopsy	autopsy	ADJ
fnp-3050	486	20	(	(	PUNCT
fnp-3050	486	21	confirmed	confirm	VERB
fnp-3050	486	22	ad	ad	NOUN
fnp-3050	486	23	)	)	PUNCT
fnp-3050	486	24	were	be	AUX
fnp-3050	486	25	studied	study	VERB
fnp-3050	486	26	;	;	PUNCT
fnp-3050	486	27	204	204	NUM
fnp-3050	486	28	with	with	ADP
fnp-3050	486	29	the	the	DET
fnp-3050	486	30	clinical	clinical	ADJ
fnp-3050	486	31	ad	ad	NOUN
fnp-3050	486	32	diagnosis	diagnosis	NOUN
fnp-3050	486	33	had	have	VERB
fnp-3050	486	34	no	no	DET
fnp-3050	486	35	adnc	adnc	ADJ
fnp-3050	486	36	(	(	PUNCT
fnp-3050	486	37	ad	ad	NOUN
fnp-3050	486	38	-	-	PUNCT
fnp-3050	486	39	mimics	mimic	NOUN
fnp-3050	486	40	)	)	PUNCT
fnp-3050	486	41	,	,	PUNCT
fnp-3050	486	42	while	while	SCONJ
fnp-3050	486	43	253	253	NUM
fnp-3050	486	44	participants	participant	NOUN
fnp-3050	486	45	with	with	ADP
fnp-3050	486	46	negative	negative	ADJ
fnp-3050	486	47	clinical	clinical	ADJ
fnp-3050	486	48	ad	ad	NOUN
fnp-3050	486	49	diagnosis	diagnosis	NOUN
fnp-3050	486	50	had	have	VERB
fnp-3050	486	51	adnc	adnc	ADJ
fnp-3050	486	52	(	(	PUNCT
fnp-3050	486	53	unidentified	unidentified	ADJ
fnp-3050	486	54	ad	ad	NOUN
fnp-3050	486	55	)	)	PUNCT
fnp-3050	486	56	.	.	PUNCT
fnp-3050	487	1	compared	compare	VERB
fnp-3050	487	2	to	to	PART
fnp-3050	487	3	confirmed	confirm	VERB
fnp-3050	487	4	ad	ad	NOUN
fnp-3050	487	5	cases	case	NOUN
fnp-3050	487	6	,	,	PUNCT
fnp-3050	487	7	ad	ad	NOUN
fnp-3050	487	8	-	-	PUNCT
fnp-3050	487	9	mimics	mimics	NOUN
fnp-3050	487	10	(	(	PUNCT
fnp-3050	487	11	ftld	ftld	NOUN
fnp-3050	487	12	-	-	PUNCT
fnp-3050	487	13	tau	tau	PROPN
fnp-3050	487	14	,	,	PUNCT
fnp-3050	487	15	hippocampal	hippocampal	ADJ
fnp-3050	487	16	sclerosis	sclerosis	NOUN
fnp-3050	487	17	,	,	PUNCT
fnp-3050	487	18	cerebrovascular	cerebrovascular	ADJ
fnp-3050	487	19	pathology	pathology	NOUN
fnp-3050	487	20	,	,	PUNCT
fnp-3050	487	21	etc	etc	X
fnp-3050	487	22	.	.	X
fnp-3050	487	23	)	)	PUNCT
fnp-3050	487	24	had	have	VERB
fnp-3050	487	25	less	less	ADV
fnp-3050	487	26	severe	severe	ADJ
fnp-3050	487	27	cognitive	cognitive	ADJ
fnp-3050	487	28	impairment	impairment	NOUN
fnp-3050	488	1	[	[	X
fnp-3050	488	2	308	308	NUM
fnp-3050	488	3	]	]	PUNCT
fnp-3050	488	4	.	.	PUNCT
fnp-3050	489	1	special	special	ADJ
fnp-3050	489	2	practical	practical	ADJ
fnp-3050	489	3	considerations	consideration	NOUN
fnp-3050	489	4	for	for	ADP
fnp-3050	489	5	the	the	DET
fnp-3050	489	6	diagnosis	diagnosis	NOUN
fnp-3050	489	7	of	of	ADP
fnp-3050	489	8	essential	essential	ADJ
fnp-3050	489	9	co	co	NOUN
fnp-3050	489	10	-	-	NOUN
fnp-3050	489	11	pathologies	pathology	NOUN
fnp-3050	489	12	and	and	CCONJ
fnp-3050	489	13	their	their	PRON
fnp-3050	489	14	relations	relation	NOUN
fnp-3050	489	15	with	with	ADP
fnp-3050	489	16	ad	ad	NOUN
fnp-3050	489	17	were	be	AUX
fnp-3050	489	18	given	give	VERB
fnp-3050	489	19	recently	recently	ADV
fnp-3050	489	20	[	[	X
fnp-3050	489	21	174	174	NUM
fnp-3050	489	22	]	]	PUNCT
fnp-3050	489	23	.	.	PUNCT
fnp-3050	490	1	argyrophilic	argyrophilic	ADJ
fnp-3050	490	2	grain	grain	NOUN
fnp-3050	490	3	disease	disease	NOUN
fnp-3050	490	4	(	(	PUNCT
fnp-3050	490	5	agd	agd	PROPN
fnp-3050	490	6	)	)	PUNCT
fnp-3050	490	7	,	,	PUNCT
fnp-3050	490	8	a	a	DET
fnp-3050	490	9	limbic	limbic	NOUN
fnp-3050	490	10	-	-	PUNCT
fnp-3050	490	11	predominant	predominant	ADJ
fnp-3050	490	12	4r	4r	NOUN
fnp-3050	490	13	-	-	PUNCT
fnp-3050	490	14	tauopathy	tauopathy	NOUN
fnp-3050	490	15	,	,	PUNCT
fnp-3050	490	16	with	with	ADP
fnp-3050	490	17	grain	grain	NOUN
fnp-3050	490	18	-	-	PUNCT
fnp-3050	490	19	like	like	ADJ
fnp-3050	490	20	deposits	deposit	NOUN
fnp-3050	490	21	in	in	ADP
fnp-3050	490	22	neuritic	neuritic	ADJ
fnp-3050	490	23	dendrites	dendrite	NOUN
fnp-3050	490	24	,	,	PUNCT
fnp-3050	490	25	oligodendroglial	oligodendroglial	ADJ
fnp-3050	490	26	inclusions	inclusion	NOUN
fnp-3050	490	27	(	(	PUNCT
fnp-3050	490	28	“	"	PUNCT
fnp-3050	490	29	coiled	coil	VERB
fnp-3050	490	30	bodies	body	NOUN
fnp-3050	490	31	”	"	PUNCT
fnp-3050	490	32	)	)	PUNCT
fnp-3050	490	33	,	,	PUNCT
fnp-3050	490	34	ramified	ramify	VERB
fnp-3050	490	35	astrocytes	astrocyte	NOUN
fnp-3050	490	36	,	,	PUNCT
fnp-3050	490	37	and	and	CCONJ
fnp-3050	490	38	ballooned	balloon	VERB
fnp-3050	490	39	neurons	neuron	NOUN
fnp-3050	490	40	in	in	ADP
fnp-3050	490	41	the	the	DET
fnp-3050	490	42	amygdala	amygdala	NOUN
fnp-3050	490	43	,	,	PUNCT
fnp-3050	490	44	hippocampus	hippocampus	NOUN
fnp-3050	490	45	and	and	CCONJ
fnp-3050	490	46	mtls	mtls	VERB
fnp-3050	490	47	[	[	PUNCT
fnp-3050	490	48	309	309	NUM
fnp-3050	490	49	]	]	PUNCT
fnp-3050	490	50	,	,	PUNCT
fnp-3050	490	51	represents	represent	VERB
fnp-3050	490	52	an	an	DET
fnp-3050	490	53	age	age	NOUN
fnp-3050	490	54	-	-	PUNCT
fnp-3050	490	55	related	relate	VERB
fnp-3050	490	56	disorder	disorder	NOUN
fnp-3050	490	57	and	and	CCONJ
fnp-3050	490	58	has	have	AUX
fnp-3050	490	59	been	be	AUX
fnp-3050	490	60	reported	report	VERB
fnp-3050	490	61	in	in	ADP
fnp-3050	490	62	up	up	ADP
fnp-3050	490	63	to	to	PART
fnp-3050	490	64	25	25	NUM
fnp-3050	490	65	%	%	NOUN
fnp-3050	490	66	ad	ad	NOUN
fnp-3050	490	67	cases	case	NOUN
fnp-3050	490	68	[	[	X
fnp-3050	490	69	310	310	NUM
fnp-3050	490	70	]	]	PUNCT
fnp-3050	490	71	,	,	PUNCT
fnp-3050	490	72	and	and	CCONJ
fnp-3050	490	73	rarely	rarely	ADV
fnp-3050	490	74	occurs	occur	VERB
fnp-3050	490	75	before	before	ADP
fnp-3050	490	76	the	the	DET
fnp-3050	490	77	age	age	NOUN
fnp-3050	490	78	of	of	ADP
fnp-3050	490	79	75	75	NUM
fnp-3050	490	80	[	[	X
fnp-3050	490	81	311	311	NUM
fnp-3050	490	82	]	]	PUNCT
fnp-3050	490	83	.	.	PUNCT
fnp-3050	491	1	aging	age	VERB
fnp-3050	491	2	-	-	PUNCT
fnp-3050	491	3	related	relate	VERB
fnp-3050	491	4	tau	tau	PROPN
fnp-3050	491	5	astrogliopathy	astrogliopathy	ADJ
fnp-3050	491	6	(	(	PUNCT
fnp-3050	491	7	artag	artag	ADJ
fnp-3050	491	8	)	)	PUNCT
fnp-3050	491	9	is	be	AUX
fnp-3050	491	10	defined	define	VERB
fnp-3050	491	11	by	by	ADP
fnp-3050	491	12	the	the	DET
fnp-3050	491	13	presence	presence	NOUN
fnp-3050	491	14	of	of	ADP
fnp-3050	491	15	two	two	NUM
fnp-3050	491	16	types	type	NOUN
fnp-3050	491	17	of	of	ADP
fnp-3050	491	18	tau	tau	NOUN
fnp-3050	491	19	-	-	PUNCT
fnp-3050	491	20	bearing	bear	VERB
fnp-3050	491	21	astrocytes	astrocyte	NOUN
fnp-3050	491	22	:	:	PUNCT
fnp-3050	491	23	thorn	thorn	NOUN
fnp-3050	491	24	-	-	PUNCT
fnp-3050	491	25	shaped	shape	VERB
fnp-3050	491	26	and	and	CCONJ
fnp-3050	491	27	granular	granular	ADJ
fnp-3050	491	28	/	/	SYM
fnp-3050	491	29	fuzzy	fuzzy	ADJ
fnp-3050	491	30	astrocytes	astrocyte	NOUN
fnp-3050	491	31	in	in	ADP
fnp-3050	491	32	the	the	DET
fnp-3050	491	33	brains	brain	NOUN
fnp-3050	491	34	of	of	ADP
fnp-3050	491	35	old	old	ADJ
fnp-3050	491	36	-	-	PUNCT
fnp-3050	491	37	aged	aged	ADJ
fnp-3050	491	38	individuals	individual	NOUN
fnp-3050	491	39	in	in	ADP
fnp-3050	491	40	different	different	ADJ
fnp-3050	491	41	locations	location	NOUN
fnp-3050	491	42	and	and	CCONJ
fnp-3050	491	43	anatomical	anatomical	ADJ
fnp-3050	491	44	regions	region	NOUN
fnp-3050	491	45	(	(	PUNCT
fnp-3050	491	46	subependymal	subependymal	ADJ
fnp-3050	491	47	,	,	PUNCT
fnp-3050	491	48	subpial	subpial	ADJ
fnp-3050	491	49	,	,	PUNCT
fnp-3050	491	50	perivascular	perivascular	ADJ
fnp-3050	491	51	,	,	PUNCT
fnp-3050	491	52	white	white	ADJ
fnp-3050	491	53	and	and	CCONJ
fnp-3050	491	54	gray	gray	ADJ
fnp-3050	491	55	matter	matter	NOUN
fnp-3050	491	56	[	[	X
fnp-3050	491	57	312	312	NUM
fnp-3050	491	58	,	,	PUNCT
fnp-3050	491	59	313	313	NUM
fnp-3050	491	60	]	]	PUNCT
fnp-3050	491	61	.	.	PUNCT
fnp-3050	492	1	among	among	ADP
fnp-3050	492	2	additional	additional	ADJ
fnp-3050	492	3	pathological	pathological	ADJ
fnp-3050	492	4	changes	change	NOUN
fnp-3050	492	5	in	in	ADP
fnp-3050	492	6	ad	ad	NOUN
fnp-3050	492	7	is	be	AUX
fnp-3050	492	8	granulovacuolar	granulovacuolar	ADJ
fnp-3050	492	9	degeneration	degeneration	NOUN
fnp-3050	492	10	(	(	PUNCT
fnp-3050	492	11	gvd	gvd	PROPN
fnp-3050	492	12	)	)	PUNCT
fnp-3050	492	13	,	,	PUNCT
fnp-3050	492	14	characterized	characterize	VERB
fnp-3050	492	15	as	as	ADP
fnp-3050	492	16	3	3	NUM
fnp-3050	492	17	-	-	SYM
fnp-3050	492	18	5	5	NUM
fnp-3050	492	19	μm	μm	NUM
fnp-3050	492	20	vesicles	vesicle	NOUN
fnp-3050	492	21	bound	bind	VERB
fnp-3050	492	22	by	by	ADP
fnp-3050	492	23	a	a	DET
fnp-3050	492	24	unit	unit	NOUN
fnp-3050	492	25	membrane	membrane	NOUN
fnp-3050	492	26	,	,	PUNCT
fnp-3050	492	27	most	most	ADV
fnp-3050	492	28	frequently	frequently	ADV
fnp-3050	492	29	occurring	occur	VERB
fnp-3050	492	30	in	in	ADP
fnp-3050	492	31	the	the	DET
fnp-3050	492	32	pyramidal	pyramidal	ADJ
fnp-3050	492	33	neurons	neuron	NOUN
fnp-3050	492	34	of	of	ADP
fnp-3050	492	35	the	the	DET
fnp-3050	492	36	hippocampus	hippocampus	NOUN
fnp-3050	492	37	,	,	PUNCT
fnp-3050	492	38	usually	usually	ADV
fnp-3050	492	39	in	in	ADP
fnp-3050	492	40	association	association	NOUN
fnp-3050	492	41	with	with	ADP
fnp-3050	492	42	nfts	nft	NOUN
fnp-3050	492	43	.	.	PUNCT
fnp-3050	493	1	their	their	PRON
fnp-3050	493	2	origin	origin	NOUN
fnp-3050	493	3	and	and	CCONJ
fnp-3050	493	4	significance	significance	NOUN
fnp-3050	493	5	are	be	AUX
fnp-3050	493	6	unclear	unclear	ADJ
fnp-3050	493	7	.	.	PUNCT
fnp-3050	494	1	despite	despite	SCONJ
fnp-3050	494	2	the	the	DET
fnp-3050	494	3	strong	strong	ADJ
fnp-3050	494	4	association	association	NOUN
fnp-3050	494	5	between	between	ADP
fnp-3050	494	6	tau	tau	PROPN
fnp-3050	494	7	aggregation	aggregation	NOUN
fnp-3050	494	8	and	and	CCONJ
fnp-3050	494	9	granulovacuolar	granulovacuolar	ADJ
fnp-3050	494	10	degeneration	degeneration	NOUN
fnp-3050	494	11	body	body	NOUN
fnp-3050	494	12	(	(	PUNCT
fnp-3050	494	13	gvb	gvb	NOUN
fnp-3050	494	14	)	)	PUNCT
fnp-3050	494	15	formation	formation	NOUN
fnp-3050	494	16	[	[	X
fnp-3050	494	17	314	314	NUM
fnp-3050	494	18	]	]	PUNCT
fnp-3050	494	19	,	,	PUNCT
fnp-3050	494	20	intracellular	intracellular	ADJ
fnp-3050	494	21	aggregates	aggregate	NOUN
fnp-3050	494	22	of	of	ADP
fnp-3050	494	23	proteins	protein	NOUN
fnp-3050	494	24	other	other	ADJ
fnp-3050	494	25	than	than	SCONJ
fnp-3050	494	26	tau	tau	PROPN
fnp-3050	494	27	can	can	AUX
fnp-3050	494	28	also	also	ADV
fnp-3050	494	29	induce	induce	VERB
fnp-3050	494	30	gvb	gvb	NOUN
fnp-3050	494	31	formation	formation	NOUN
fnp-3050	494	32	,	,	PUNCT
fnp-3050	494	33	which	which	PRON
fnp-3050	494	34	needs	need	VERB
fnp-3050	494	35	further	further	ADJ
fnp-3050	494	36	elucidation	elucidation	NOUN
fnp-3050	494	37	[	[	X
fnp-3050	494	38	315	315	NUM
fnp-3050	494	39	]	]	PUNCT
fnp-3050	494	40	.	.	PUNCT
fnp-3050	495	1	the	the	DET
fnp-3050	495	2	granule	granule	NOUN
fnp-3050	495	3	of	of	ADP
fnp-3050	495	4	the	the	DET
fnp-3050	495	5	gvd	gvd	NOUN
fnp-3050	495	6	is	be	AUX
fnp-3050	495	7	immunolabeled	immunolabele	VERB
fnp-3050	495	8	by	by	ADP
fnp-3050	495	9	antibodies	antibody	NOUN
fnp-3050	495	10	against	against	ADP
fnp-3050	495	11	tubulin	tubulin	NOUN
fnp-3050	495	12	,	,	PUNCT
fnp-3050	495	13	ubiquitin	ubiquitin	NOUN
fnp-3050	495	14	,	,	PUNCT
fnp-3050	495	15	neurofilament	neurofilament	NOUN
fnp-3050	495	16	,	,	PUNCT
fnp-3050	495	17	and	and	CCONJ
fnp-3050	495	18	tau	tau	X
fnp-3050	496	1	[	[	X
fnp-3050	496	2	31	31	NUM
fnp-3050	496	3	]	]	PUNCT
fnp-3050	496	4	.	.	PUNCT
fnp-3050	497	1	they	they	PRON
fnp-3050	497	2	correlate	correlate	VERB
fnp-3050	497	3	with	with	ADP
fnp-3050	497	4	nft	nft	PROPN
fnp-3050	497	5	density	density	PROPN
fnp-3050	497	6	,	,	PUNCT
fnp-3050	497	7	suggesting	suggest	VERB
fnp-3050	497	8	that	that	SCONJ
fnp-3050	497	9	they	they	PRON
fnp-3050	497	10	may	may	AUX
fnp-3050	497	11	be	be	AUX
fnp-3050	497	12	a	a	DET
fnp-3050	497	13	cellular	cellular	ADJ
fnp-3050	497	14	response	response	NOUN
fnp-3050	497	15	to	to	ADP
fnp-3050	497	16	neuronal	neuronal	ADJ
fnp-3050	497	17	damage	damage	NOUN
fnp-3050	497	18	or	or	CCONJ
fnp-3050	497	19	late	late	ADJ
fnp-3050	497	20	-	-	PUNCT
fnp-3050	497	21	stage	stage	NOUN
fnp-3050	497	22	autophagic	autophagic	NOUN
fnp-3050	497	23	vacuoles	vacuole	NOUN
fnp-3050	497	24	[	[	X
fnp-3050	497	25	316	316	NUM
fnp-3050	497	26	]	]	PUNCT
fnp-3050	497	27	.	.	PUNCT
fnp-3050	498	1	necrosome	necrosome	ADJ
fnp-3050	498	2	complex	complex	NOUN
fnp-3050	498	3	detected	detect	VERB
fnp-3050	498	4	in	in	ADP
fnp-3050	498	5	gvd	gvd	NOUN
fnp-3050	498	6	is	be	AUX
fnp-3050	498	7	associated	associate	VERB
fnp-3050	498	8	with	with	ADP
fnp-3050	498	9	neuron	neuron	NOUN
fnp-3050	498	10	loss	loss	NOUN
fnp-3050	498	11	in	in	ADP
fnp-3050	498	12	ad	ad	NOUN
fnp-3050	498	13	[	[	X
fnp-3050	498	14	317	317	NUM
fnp-3050	498	15	]	]	PUNCT
fnp-3050	498	16	.	.	PUNCT
fnp-3050	499	1	recent	recent	ADJ
fnp-3050	499	2	clinicopathological	clinicopathological	ADJ
fnp-3050	499	3	studies	study	NOUN
fnp-3050	499	4	have	have	AUX
fnp-3050	499	5	shown	show	VERB
fnp-3050	499	6	that	that	SCONJ
fnp-3050	499	7	the	the	DET
fnp-3050	499	8	complex	complex	ADJ
fnp-3050	499	9	cascades	cascade	NOUN
fnp-3050	499	10	of	of	ADP
fnp-3050	499	11	the	the	DET
fnp-3050	499	12	underlying	underlie	VERB
fnp-3050	499	13	pathologies	pathology	NOUN
fnp-3050	499	14	in	in	ADP
fnp-3050	499	15	most	most	ADJ
fnp-3050	499	16	elderly	elderly	ADJ
fnp-3050	499	17	patients	patient	NOUN
fnp-3050	499	18	may	may	AUX
fnp-3050	499	19	lead	lead	VERB
fnp-3050	499	20	to	to	ADP
fnp-3050	499	21	cognitive	cognitive	ADJ
fnp-3050	499	22	decline	decline	NOUN
fnp-3050	499	23	,	,	PUNCT
fnp-3050	499	24	and	and	CCONJ
fnp-3050	499	25	that	that	SCONJ
fnp-3050	499	26	the	the	DET
fnp-3050	499	27	number	number	NOUN
fnp-3050	499	28	of	of	ADP
fnp-3050	499	29	possible	possible	ADJ
fnp-3050	499	30	combinations	combination	NOUN
fnp-3050	499	31	due	due	ADP
fnp-3050	499	32	to	to	ADP
fnp-3050	499	33	co	co	NOUN
fnp-3050	499	34	-	-	NOUN
fnp-3050	499	35	morbidities	morbidity	NOUN
fnp-3050	499	36	increases	increase	VERB
fnp-3050	499	37	with	with	ADP
fnp-3050	499	38	aging	age	VERB
fnp-3050	499	39	[	[	X
fnp-3050	499	40	248	248	NUM
fnp-3050	499	41	]	]	PUNCT
fnp-3050	499	42	.	.	PUNCT
fnp-3050	500	1	these	these	DET
fnp-3050	500	2	concomitant	concomitant	ADJ
fnp-3050	500	3	pathologies	pathology	NOUN
fnp-3050	500	4	may	may	AUX
fnp-3050	500	5	be	be	AUX
fnp-3050	500	6	harmful	harmful	ADJ
fnp-3050	500	7	to	to	ADP
fnp-3050	500	8	individuals	individual	NOUN
fnp-3050	500	9	with	with	ADP
fnp-3050	500	10	low	low	ADJ
fnp-3050	500	11	cognitive	cognitive	ADJ
fnp-3050	500	12	reserve	reserve	NOUN
fnp-3050	500	13	such	such	ADJ
fnp-3050	500	14	as	as	ADP
fnp-3050	500	15	patients	patient	NOUN
fnp-3050	500	16	with	with	ADP
fnp-3050	500	17	ma	ma	NOUN
fnp-3050	500	18	-	-	NOUN
fnp-3050	500	19	ad	ad	NOUN
fnp-3050	500	20	.	.	PUNCT
fnp-3050	501	1	they	they	PRON
fnp-3050	501	2	can	can	AUX
fnp-3050	501	3	cause	cause	VERB
fnp-3050	501	4	a	a	DET
fnp-3050	501	5	number	number	NOUN
fnp-3050	501	6	of	of	ADP
fnp-3050	501	7	challenges	challenge	NOUN
fnp-3050	501	8	including	include	VERB
fnp-3050	501	9	the	the	DET
fnp-3050	501	10	evaluation	evaluation	NOUN
fnp-3050	501	11	of	of	ADP
fnp-3050	501	12	the	the	DET
fnp-3050	501	13	significance	significance	NOUN
fnp-3050	501	14	of	of	ADP
fnp-3050	501	15	each	each	DET
fnp-3050	501	16	pathological	pathological	ADJ
fnp-3050	501	17	entity	entity	NOUN
fnp-3050	501	18	in	in	ADP
fnp-3050	501	19	the	the	DET
fnp-3050	501	20	manifestation	manifestation	NOUN
fnp-3050	501	21	of	of	ADP
fnp-3050	501	22	the	the	DET
fnp-3050	501	23	clinical	clinical	ADJ
fnp-3050	501	24	symptoms	symptom	NOUN
fnp-3050	501	25	,	,	PUNCT
fnp-3050	501	26	and	and	CCONJ
fnp-3050	501	27	the	the	DET
fnp-3050	501	28	threshold	threshold	NOUN
fnp-3050	501	29	of	of	ADP
fnp-3050	501	30	each	each	DET
fnp-3050	501	31	individual	individual	ADJ
fnp-3050	501	32	pathology	pathology	NOUN
fnp-3050	501	33	to	to	PART
fnp-3050	501	34	cause	cause	VERB
fnp-3050	501	35	dementia	dementia	NOUN
fnp-3050	501	36	[	[	X
fnp-3050	501	37	174	174	NUM
fnp-3050	501	38	]	]	PUNCT
fnp-3050	501	39	.	.	PUNCT
fnp-3050	502	1	total	total	ADJ
fnp-3050	502	2	burden	burden	NOUN
fnp-3050	502	3	of	of	ADP
fnp-3050	502	4	comorbid	comorbid	ADJ
fnp-3050	502	5	pathological	pathological	ADJ
fnp-3050	502	6	abnormalities	abnormality	NOUN
fnp-3050	502	7	,	,	PUNCT
fnp-3050	502	8	rather	rather	ADV
fnp-3050	502	9	than	than	ADP
fnp-3050	502	10	any	any	DET
fnp-3050	502	11	single	single	ADJ
fnp-3050	502	12	lesion	lesion	NOUN
fnp-3050	502	13	,	,	PUNCT
fnp-3050	502	14	is	be	AUX
fnp-3050	502	15	the	the	DET
fnp-3050	502	16	most	most	ADV
fnp-3050	502	17	important	important	ADJ
fnp-3050	502	18	cause	cause	NOUN
fnp-3050	502	19	of	of	ADP
fnp-3050	502	20	cognitive	cognitive	ADJ
fnp-3050	502	21	impairment	impairment	NOUN
fnp-3050	502	22	,	,	PUNCT
fnp-3050	502	23	often	often	ADV
fnp-3050	502	24	despite	despite	SCONJ
fnp-3050	502	25	clinical	clinical	ADJ
fnp-3050	502	26	diagnosis	diagnosis	NOUN
fnp-3050	502	27	of	of	ADP
fnp-3050	502	28	“	"	PUNCT
fnp-3050	502	29	only	only	ADJ
fnp-3050	502	30	”	"	PUNCT
fnp-3050	502	31	ad	ad	NOUN
fnp-3050	502	32	[	[	X
fnp-3050	502	33	318	318	NUM
fnp-3050	502	34	]	]	PUNCT
fnp-3050	502	35	.	.	PUNCT
fnp-3050	503	1	5	5	X
fnp-3050	503	2	.	.	X
fnp-3050	503	3	conclusions	conclusion	NOUN
fnp-3050	503	4	ad	ad	NOUN
fnp-3050	503	5	is	be	AUX
fnp-3050	503	6	a	a	DET
fnp-3050	503	7	heterogeneous	heterogeneous	ADJ
fnp-3050	503	8	,	,	PUNCT
fnp-3050	503	9	multifactorial	multifactorial	ADJ
fnp-3050	503	10	disorder	disorder	NOUN
fnp-3050	503	11	,	,	PUNCT
fnp-3050	503	12	manifesting	manifest	VERB
fnp-3050	503	13	clinically	clinically	ADV
fnp-3050	503	14	and	and	CCONJ
fnp-3050	503	15	morphologically	morphologically	ADV
fnp-3050	503	16	as	as	ADP
fnp-3050	503	17	several	several	ADJ
fnp-3050	503	18	subtypes	subtype	NOUN
fnp-3050	503	19	that	that	PRON
fnp-3050	503	20	have	have	VERB
fnp-3050	503	21	a	a	DET
fnp-3050	503	22	distinct	distinct	ADJ
fnp-3050	503	23	signature	signature	NOUN
fnp-3050	503	24	of	of	ADP
fnp-3050	503	25	network	network	NOUN
fnp-3050	503	26	disruptions	disruption	NOUN
fnp-3050	503	27	associated	associate	VERB
fnp-3050	503	28	with	with	ADP
fnp-3050	503	29	their	their	PRON
fnp-3050	503	30	atrophy	atrophy	NOUN
fnp-3050	503	31	pattern	pattern	NOUN
fnp-3050	503	32	and	and	CCONJ
fnp-3050	503	33	reflecting	reflect	VERB
fnp-3050	503	34	the	the	DET
fnp-3050	503	35	differential	differential	ADJ
fnp-3050	503	36	spread	spread	NOUN
fnp-3050	503	37	of	of	ADP
fnp-3050	503	38	nft	nft	PROPN
fnp-3050	503	39	pathology	pathology	PROPN
fnp-3050	503	40	and	and	CCONJ
fnp-3050	503	41	neuronal	neuronal	ADJ
fnp-3050	503	42	loss	loss	NOUN
fnp-3050	503	43	due	due	ADP
fnp-3050	503	44	to	to	ADP
fnp-3050	503	45	different	different	ADJ
fnp-3050	503	46	vulnerability	vulnerability	NOUN
fnp-3050	503	47	patterns	pattern	NOUN
fnp-3050	503	48	of	of	ADP
fnp-3050	503	49	affected	affect	VERB
fnp-3050	503	50	brain	brain	NOUN
fnp-3050	503	51	regions	region	NOUN
fnp-3050	503	52	,	,	PUNCT
fnp-3050	503	53	which	which	PRON
fnp-3050	503	54	relates	relate	VERB
fnp-3050	503	55	to	to	ADP
fnp-3050	503	56	specific	specific	ADJ
fnp-3050	503	57	molecular	molecular	ADJ
fnp-3050	503	58	-	-	PUNCT
fnp-3050	503	59	functional	functional	ADJ
fnp-3050	503	60	properties	property	NOUN
fnp-3050	503	61	of	of	ADP
fnp-3050	503	62	the	the	DET
fnp-3050	503	63	affected	affected	ADJ
fnp-3050	503	64	neuronal	neuronal	ADJ
fnp-3050	503	65	systems	system	NOUN
fnp-3050	503	66	[	[	X
fnp-3050	503	67	22	22	NUM
fnp-3050	503	68	,	,	PUNCT
fnp-3050	503	69	23	23	NUM
fnp-3050	503	70	]	]	PUNCT
fnp-3050	503	71	.	.	PUNCT
fnp-3050	504	1	the	the	DET
fnp-3050	504	2	severity	severity	NOUN
fnp-3050	504	3	of	of	ADP
fnp-3050	504	4	lesions	lesion	NOUN
fnp-3050	504	5	corresponds	correspond	VERB
fnp-3050	504	6	to	to	ADP
fnp-3050	504	7	the	the	DET
fnp-3050	504	8	“	"	PUNCT
fnp-3050	504	9	n	n	CCONJ
fnp-3050	504	10	”	"	PUNCT
fnp-3050	504	11	category	category	NOUN
fnp-3050	504	12	in	in	ADP
fnp-3050	504	13	the	the	DET
fnp-3050	504	14	new	new	ADJ
fnp-3050	504	15	a	a	PROPN
fnp-3050	504	16	/	/	SYM
fnp-3050	504	17	t	t	NOUN
fnp-3050	504	18	/	/	SYM
fnp-3050	504	19	n	n	NOUN
fnp-3050	504	20	classification	classification	NOUN
fnp-3050	504	21	for	for	ADP
fnp-3050	504	22	biomarkers	biomarker	NOUN
fnp-3050	504	23	[	[	X
fnp-3050	504	24	319	319	NUM
fnp-3050	504	25	]	]	PUNCT
fnp-3050	504	26	.	.	PUNCT
fnp-3050	505	1	the	the	DET
fnp-3050	505	2	heterogeneity	heterogeneity	NOUN
fnp-3050	505	3	of	of	ADP
fnp-3050	505	4	the	the	DET
fnp-3050	505	5	alzheimer	alzheimer	PROPN
fnp-3050	505	6	’s	’s	PART
fnp-3050	505	7	syndrome	syndrome	NOUN
fnp-3050	505	8	is	be	AUX
fnp-3050	505	9	related	relate	VERB
fnp-3050	505	10	to	to	ADP
fnp-3050	505	11	multiple	multiple	ADJ
fnp-3050	505	12	pathogenic	pathogenic	ADJ
fnp-3050	505	13	factors	factor	NOUN
fnp-3050	505	14	which	which	PRON
fnp-3050	505	15	induce	induce	VERB
fnp-3050	505	16	misfolding	misfolding	PROPN
fnp-3050	505	17	tau	tau	PROPN
fnp-3050	505	18	,	,	PUNCT
fnp-3050	505	19	aβ	aβ	PROPN
fnp-3050	505	20	,	,	PUNCT
fnp-3050	505	21	tdp-43	tdp-43	PROPN
fnp-3050	505	22	,	,	PUNCT
fnp-3050	505	23	and	and	CCONJ
fnp-3050	505	24	other	other	ADJ
fnp-3050	505	25	proteins	protein	NOUN
fnp-3050	505	26	,	,	PUNCT
fnp-3050	505	27	the	the	DET
fnp-3050	505	28	synergetic	synergetic	ADJ
fnp-3050	505	29	or	or	CCONJ
fnp-3050	505	30	additive	additive	ADJ
fnp-3050	505	31	action	action	NOUN
fnp-3050	505	32	of	of	ADP
fnp-3050	505	33	which	which	PRON
fnp-3050	505	34	results	result	VERB
fnp-3050	505	35	in	in	ADP
fnp-3050	505	36	various	various	ADJ
fnp-3050	505	37	disease	disease	NOUN
fnp-3050	505	38	phenotypes	phenotype	NOUN
fnp-3050	505	39	[	[	X
fnp-3050	505	40	320	320	NUM
fnp-3050	505	41	]	]	PUNCT
fnp-3050	505	42	.	.	PUNCT
fnp-3050	506	1	several	several	ADJ
fnp-3050	506	2	factors	factor	NOUN
fnp-3050	506	3	such	such	ADJ
fnp-3050	506	4	as	as	ADP
fnp-3050	506	5	brain	brain	NOUN
fnp-3050	506	6	resilience	resilience	NOUN
fnp-3050	506	7	may	may	AUX
fnp-3050	506	8	help	help	VERB
fnp-3050	506	9	compensate	compensate	VERB
fnp-3050	506	10	for	for	ADP
fnp-3050	506	11	these	these	DET
fnp-3050	506	12	pathologies	pathology	NOUN
fnp-3050	506	13	up	up	ADP
fnp-3050	506	14	to	to	ADP
fnp-3050	506	15	a	a	DET
fnp-3050	506	16	certain	certain	ADJ
fnp-3050	506	17	level	level	NOUN
fnp-3050	506	18	,	,	PUNCT
fnp-3050	506	19	although	although	SCONJ
fnp-3050	506	20	their	their	PRON
fnp-3050	506	21	relevance	relevance	NOUN
fnp-3050	506	22	is	be	AUX
fnp-3050	506	23	still	still	ADV
fnp-3050	506	24	poorly	poorly	ADV
fnp-3050	506	25	understood	understand	VERB
fnp-3050	506	26	.	.	PUNCT
fnp-3050	507	1	these	these	DET
fnp-3050	507	2	problems	problem	NOUN
fnp-3050	507	3	and	and	CCONJ
fnp-3050	507	4	the	the	DET
fnp-3050	507	5	increasing	increase	VERB
fnp-3050	507	6	incidence	incidence	NOUN
fnp-3050	507	7	of	of	ADP
fnp-3050	507	8	ad	ad	NOUN
fnp-3050	507	9	illustrate	illustrate	VERB
fnp-3050	507	10	its	its	PRON
fnp-3050	507	11	consequences	consequence	NOUN
fnp-3050	507	12	on	on	ADP
fnp-3050	507	13	public	public	ADJ
fnp-3050	507	14	health	health	NOUN
fnp-3050	507	15	and	and	CCONJ
fnp-3050	507	16	the	the	DET
fnp-3050	507	17	resulting	result	VERB
fnp-3050	507	18	challenges	challenge	NOUN
fnp-3050	507	19	for	for	ADP
fnp-3050	507	20	future	future	ADJ
fnp-3050	507	21	medicine	medicine	NOUN
fnp-3050	507	22	.	.	PUNCT
fnp-3050	508	1	increased	increase	VERB
fnp-3050	508	2	sensitivity	sensitivity	NOUN
fnp-3050	508	3	and	and	CCONJ
fnp-3050	508	4	specificity	specificity	NOUN
fnp-3050	508	5	of	of	ADP
fnp-3050	508	6	new	new	ADJ
fnp-3050	508	7	atn	atn	PROPN
fnp-3050	508	8	biomarker	biomarker	NOUN
fnp-3050	508	9	systems	system	NOUN
fnp-3050	508	10	and	and	CCONJ
fnp-3050	508	11	more	more	ADV
fnp-3050	508	12	extensive	extensive	ADJ
fnp-3050	508	13	clinicopathological	clinicopathological	ADJ
fnp-3050	508	14	studies	study	NOUN
fnp-3050	508	15	in	in	ADP
fnp-3050	508	16	well	well	ADV
fnp-3050	508	17	-	-	PUNCT
fnp-3050	508	18	defined	define	VERB
fnp-3050	508	19	populations	population	NOUN
fnp-3050	508	20	are	be	AUX
fnp-3050	508	21	needed	need	VERB
fnp-3050	508	22	,	,	PUNCT
fnp-3050	508	23	with	with	ADP
fnp-3050	508	24	post	post	ADJ
fnp-3050	508	25	-	-	ADJ
fnp-3050	508	26	mortem	mortem	ADJ
fnp-3050	508	27	studies	study	NOUN
fnp-3050	508	28	using	use	VERB
fnp-3050	508	29	the	the	DET
fnp-3050	508	30	updated	update	VERB
fnp-3050	508	31	nia	nia	PROPN
fnp-3050	508	32	/	/	SYM
fnp-3050	508	33	aa	aa	PROPN
fnp-3050	508	34	criteria	criterion	NOUN
fnp-3050	508	35	.	.	PUNCT
fnp-3050	509	1	the	the	DET
fnp-3050	509	2	recent	recent	ADJ
fnp-3050	509	3	advent	advent	NOUN
fnp-3050	509	4	of	of	ADP
fnp-3050	509	5	tau	tau	PROPN
fnp-3050	509	6	pet	pet	ADJ
fnp-3050	509	7	and	and	CCONJ
fnp-3050	509	8	novel	novel	ADJ
fnp-3050	509	9	imaging	imaging	NOUN
fnp-3050	509	10	and	and	CCONJ
fnp-3050	509	11	fluid	fluid	NOUN
fnp-3050	509	12	-	-	PUNCT
fnp-3050	509	13	based	base	VERB
fnp-3050	509	14	(	(	PUNCT
fnp-3050	509	15	csf	csf	NOUN
fnp-3050	509	16	)	)	PUNCT
fnp-3050	509	17	biomarkers	biomarker	NOUN
fnp-3050	509	18	allows	allow	VERB
fnp-3050	509	19	us	we	PRON
fnp-3050	509	20	to	to	PART
fnp-3050	509	21	study	study	VERB
fnp-3050	509	22	the	the	DET
fnp-3050	509	23	temporal	temporal	ADJ
fnp-3050	509	24	progression	progression	NOUN
fnp-3050	509	25	of	of	ADP
fnp-3050	509	26	tau	tau	PROPN
fnp-3050	509	27	pathology	pathology	NOUN
fnp-3050	509	28	in	in	ADP
fnp-3050	509	29	vivo	vivo	NOUN
fnp-3050	509	30	[	[	X
fnp-3050	509	31	321	321	NUM
fnp-3050	509	32	,	,	PUNCT
fnp-3050	509	33	322	322	NUM
fnp-3050	509	34	]	]	PUNCT
fnp-3050	509	35	.	.	PUNCT
fnp-3050	510	1	improving	improve	VERB
fnp-3050	510	2	methods	method	NOUN
fnp-3050	510	3	for	for	ADP
fnp-3050	510	4	disease	disease	NOUN
fnp-3050	510	5	detection	detection	NOUN
fnp-3050	510	6	and	and	CCONJ
fnp-3050	510	7	monitoring	monitor	VERB
fnp-3050	510	8	its	its	PRON
fnp-3050	510	9	progression	progression	NOUN
fnp-3050	510	10	may	may	AUX
fnp-3050	510	11	hopefully	hopefully	ADV
fnp-3050	510	12	lead	lead	VERB
fnp-3050	510	13	to	to	ADP
fnp-3050	510	14	the	the	DET
fnp-3050	510	15	development	development	NOUN
fnp-3050	510	16	and	and	CCONJ
fnp-3050	510	17	refinement	refinement	NOUN
fnp-3050	510	18	of	of	ADP
fnp-3050	510	19	tau	tau	NOUN
fnp-3050	510	20	-	-	PUNCT
fnp-3050	510	21	based	base	VERB
fnp-3050	510	22	therapeutics	therapeutic	NOUN
fnp-3050	510	23	.	.	PUNCT
fnp-3050	511	1	in	in	ADP
fnp-3050	511	2	the	the	DET
fnp-3050	511	3	interest	interest	NOUN
fnp-3050	511	4	of	of	ADP
fnp-3050	511	5	optimizing	optimize	VERB
fnp-3050	511	6	the	the	DET
fnp-3050	511	7	clinical	clinical	ADJ
fnp-3050	511	8	diagnosis	diagnosis	NOUN
fnp-3050	511	9	of	of	ADP
fnp-3050	511	10	ad	ad	NOUN
fnp-3050	511	11	and	and	CCONJ
fnp-3050	511	12	related	related	ADJ
fnp-3050	511	13	disorders	disorder	NOUN
fnp-3050	511	14	,	,	PUNCT
fnp-3050	511	15	neuropathological	neuropathological	ADJ
fnp-3050	511	16	studies	study	NOUN
fnp-3050	511	17	should	should	AUX
fnp-3050	511	18	use	use	VERB
fnp-3050	511	19	a	a	DET
fnp-3050	511	20	wide	wide	ADJ
fnp-3050	511	21	range	range	NOUN
fnp-3050	511	22	of	of	ADP
fnp-3050	511	23	molecular	molecular	ADJ
fnp-3050	511	24	pathological	pathological	ADJ
fnp-3050	511	25	methods	method	NOUN
fnp-3050	511	26	and	and	CCONJ
fnp-3050	511	27	should	should	AUX
fnp-3050	511	28	evaluate	evaluate	VERB
fnp-3050	511	29	multiple	multiple	ADJ
fnp-3050	511	30	cns	cns	NOUN
fnp-3050	511	31	regions	region	NOUN
fnp-3050	511	32	.	.	PUNCT
fnp-3050	512	1	an	an	DET
fnp-3050	512	2	optimal	optimal	ADJ
fnp-3050	512	3	and	and	CCONJ
fnp-3050	512	4	less	less	ADV
fnp-3050	512	5	cost	cost	NOUN
fnp-3050	512	6	-	-	PUNCT
fnp-3050	512	7	intensive	intensive	ADJ
fnp-3050	512	8	strategy	strategy	NOUN
fnp-3050	512	9	would	would	AUX
fnp-3050	512	10	be	be	AUX
fnp-3050	512	11	to	to	PART
fnp-3050	512	12	screen	screen	VERB
fnp-3050	512	13	specifically	specifically	ADV
fnp-3050	512	14	neurodegeneration	neurodegeneration	NOUN
fnp-3050	512	15	-	-	PUNCT
fnp-3050	512	16	related	relate	VERB
fnp-3050	512	17	proteins	protein	NOUN
fnp-3050	512	18	and	and	CCONJ
fnp-3050	512	19	to	to	PART
fnp-3050	512	20	examine	examine	VERB
fnp-3050	512	21	their	their	PRON
fnp-3050	512	22	cross	cross	NOUN
fnp-3050	512	23	reactions	reaction	NOUN
fnp-3050	512	24	.	.	PUNCT
fnp-3050	513	1	the	the	DET
fnp-3050	513	2	recent	recent	ADJ
fnp-3050	513	3	correlative	correlative	ADJ
fnp-3050	513	4	work	work	NOUN
fnp-3050	513	5	on	on	ADP
fnp-3050	513	6	concomitant	concomitant	ADJ
fnp-3050	513	7	pathologies	pathology	NOUN
fnp-3050	513	8	has	have	AUX
fnp-3050	513	9	provide	provide	VERB
fnp-3050	513	10	insight	insight	NOUN
fnp-3050	513	11	into	into	ADP
fnp-3050	513	12	the	the	DET
fnp-3050	513	13	interactions	interaction	NOUN
fnp-3050	513	14	of	of	ADP
fnp-3050	513	15	the	the	DET
fnp-3050	513	16	various	various	ADJ
fnp-3050	513	17	pathologies	pathology	NOUN
fnp-3050	513	18	and	and	CCONJ
fnp-3050	513	19	their	their	PRON
fnp-3050	513	20	roles	role	NOUN
fnp-3050	513	21	in	in	ADP
fnp-3050	513	22	causing	cause	VERB
fnp-3050	513	23	dementing	demente	VERB
fnp-3050	513	24	symptoms	symptom	NOUN
fnp-3050	513	25	.	.	PUNCT
fnp-3050	514	1	interdisciplinary	interdisciplinary	ADJ
fnp-3050	514	2	studies	study	NOUN
fnp-3050	514	3	may	may	AUX
fnp-3050	514	4	improve	improve	VERB
fnp-3050	514	5	our	our	PRON
fnp-3050	514	6	knowledge	knowledge	NOUN
fnp-3050	514	7	about	about	ADP
fnp-3050	514	8	the	the	DET
fnp-3050	514	9	pathogenesis	pathogenesis	NOUN
fnp-3050	514	10	of	of	ADP
fnp-3050	514	11	the	the	DET
fnp-3050	514	12	heterogeneous	heterogeneous	ADJ
fnp-3050	514	13	manifestation	manifestation	NOUN
fnp-3050	514	14	of	of	ADP
fnp-3050	514	15	ad	ad	NOUN
fnp-3050	514	16	and	and	CCONJ
fnp-3050	514	17	promote	promote	VERB
fnp-3050	514	18	methods	method	NOUN
fnp-3050	514	19	for	for	ADP
fnp-3050	514	20	its	its	PRON
fnp-3050	514	21	early	early	ADJ
fnp-3050	514	22	diagnosis	diagnosis	NOUN
fnp-3050	514	23	as	as	ADP
fnp-3050	514	24	the	the	DET
fnp-3050	514	25	basis	basis	NOUN
fnp-3050	514	26	for	for	ADP
fnp-3050	514	27	further	far	ADV
fnp-3050	514	28	preventive	preventive	ADJ
fnp-3050	514	29	and	and	CCONJ
fnp-3050	514	30	successful	successful	ADJ
fnp-3050	514	31	disease	disease	NOUN
fnp-3050	514	32	-	-	PUNCT
fnp-3050	514	33	modifying	modify	VERB
fnp-3050	514	34	therapeutic	therapeutic	ADJ
fnp-3050	514	35	measures	measure	NOUN
fnp-3050	514	36	.	.	PUNCT
fnp-3050	515	1	funding	fund	VERB
fnp-3050	515	2	this	this	DET
fnp-3050	515	3	research	research	NOUN
fnp-3050	515	4	was	be	AUX
fnp-3050	515	5	partially	partially	ADV
fnp-3050	515	6	funded	fund	VERB
fnp-3050	515	7	by	by	ADP
fnp-3050	515	8	the	the	DET
fnp-3050	515	9	society	society	NOUN
fnp-3050	515	10	for	for	ADP
fnp-3050	515	11	the	the	DET
fnp-3050	515	12	promotion	promotion	NOUN
fnp-3050	515	13	of	of	ADP
fnp-3050	515	14	research	research	NOUN
fnp-3050	515	15	in	in	ADP
fnp-3050	515	16	experimental	experimental	ADJ
fnp-3050	515	17	neurology	neurology	NOUN
fnp-3050	515	18	,	,	PUNCT
fnp-3050	515	19	vienna	vienna	PROPN
fnp-3050	515	20	,	,	PUNCT
fnp-3050	515	21	austria	austria	PROPN
fnp-3050	515	22	.	.	PUNCT
fnp-3050	516	1	acknowledgments	acknowledgment	NOUN
fnp-3050	516	2	the	the	DET
fnp-3050	516	3	author	author	NOUN
fnp-3050	516	4	thanks	thank	NOUN
fnp-3050	516	5	mr	mr	PROPN
fnp-3050	516	6	.	.	PROPN
fnp-3050	516	7	e.	e.	PROPN
fnp-3050	516	8	mitter	mitter	PROPN
fnp-3050	516	9	-	-	PUNCT
fnp-3050	516	10	ferstl	ferstl	NOUN
fnp-3050	516	11	,	,	PUNCT
fnp-3050	516	12	phd	phd	NOUN
fnp-3050	516	13	,	,	PUNCT
fnp-3050	516	14	for	for	ADP
fnp-3050	516	15	secretarial	secretarial	ADJ
fnp-3050	516	16	and	and	CCONJ
fnp-3050	516	17	editorial	editorial	ADJ
fnp-3050	516	18	work	work	NOUN
fnp-3050	516	19	.	.	PUNCT
fnp-3050	517	1	conflicts	conflict	NOUN
fnp-3050	517	2	of	of	ADP
fnp-3050	517	3	interest	interest	NOUN
fnp-3050	517	4	the	the	DET
fnp-3050	517	5	author	author	NOUN
fnp-3050	517	6	declares	declare	VERB
fnp-3050	517	7	no	no	DET
fnp-3050	517	8	conflict	conflict	NOUN
fnp-3050	517	9	of	of	ADP
fnp-3050	517	10	interest	interest	NOUN
fnp-3050	517	11	.	.	PUNCT
fnp-3050	518	1	references	reference	NOUN
fnp-3050	518	2	1	1	NUM
fnp-3050	518	3	.	.	PUNCT
fnp-3050	518	4	alzheimer's	alzheimer's	NOUN
fnp-3050	518	5	-	-	PUNCT
fnp-3050	518	6	association	association	NOUN
fnp-3050	518	7	(	(	PUNCT
fnp-3050	518	8	2018	2018	NUM
fnp-3050	518	9	)	)	PUNCT
fnp-3050	518	10	2018	2018	NUM
fnp-3050	518	11	alzheimer	alzheimer	NOUN
fnp-3050	518	12	's	's	PART
fnp-3050	518	13	disease	disease	NOUN
fnp-3050	518	14	facts	fact	NOUN
fnp-3050	518	15	and	and	CCONJ
fnp-3050	518	16	figures	figure	NOUN
fnp-3050	518	17	.	.	PUNCT
fnp-3050	519	1	alzheimers	alzheimers	PROPN
fnp-3050	519	2	dement	dement	PROPN
fnp-3050	519	3	14:367	14:367	PROPN
fnp-3050	519	4	-	-	SYM
fnp-3050	519	5	429	429	NUM
fnp-3050	519	6	2	2	NUM
fnp-3050	519	7	.	.	PUNCT
fnp-3050	520	1	farfel	farfel	PROPN
fnp-3050	520	2	jm	jm	PROPN
fnp-3050	520	3	,	,	PUNCT
fnp-3050	520	4	yu	yu	PROPN
fnp-3050	520	5	l	l	PROPN
fnp-3050	520	6	,	,	PUNCT
fnp-3050	520	7	boyle	boyle	PROPN
fnp-3050	520	8	pa	pa	PROPN
fnp-3050	520	9	,	,	PUNCT
fnp-3050	520	10	leurgans	leurgans	PROPN
fnp-3050	520	11	s	s	PART
fnp-3050	520	12	,	,	PUNCT
fnp-3050	520	13	shah	shah	PROPN
fnp-3050	520	14	rc	rc	PROPN
fnp-3050	520	15	,	,	PUNCT
fnp-3050	520	16	schneider	schneider	PROPN
fnp-3050	520	17	ja	ja	PROPN
fnp-3050	520	18	,	,	PUNCT
fnp-3050	520	19	bennett	bennett	PROPN
fnp-3050	520	20	da	da	PROPN
fnp-3050	520	21	(	(	PUNCT
fnp-3050	520	22	2019	2019	NUM
fnp-3050	520	23	)	)	PUNCT
fnp-3050	520	24	alzheimer	alzheimer	PROPN
fnp-3050	520	25	's	's	PART
fnp-3050	520	26	disease	disease	NOUN
fnp-3050	520	27	frequency	frequency	NOUN
fnp-3050	520	28	peaks	peak	NOUN
fnp-3050	520	29	in	in	ADP
fnp-3050	520	30	the	the	DET
fnp-3050	520	31	tenth	tenth	ADJ
fnp-3050	520	32	decade	decade	NOUN
fnp-3050	520	33	and	and	CCONJ
fnp-3050	520	34	is	be	AUX
fnp-3050	520	35	lower	low	ADJ
fnp-3050	520	36	afterwards	afterwards	ADV
fnp-3050	520	37	.	.	PUNCT
fnp-3050	521	1	acta	acta	PROPN
fnp-3050	521	2	neuropathol	neuropathol	PROPN
fnp-3050	521	3	commun	commun	PROPN
fnp-3050	521	4	7:104	7:104	PROPN
fnp-3050	521	5	3	3	X
fnp-3050	521	6	.	.	PUNCT
fnp-3050	522	1	jellinger	jellinger	PROPN
fnp-3050	522	2	ka	ka	PROPN
fnp-3050	522	3	,	,	PUNCT
fnp-3050	522	4	attems	attem	VERB
fnp-3050	522	5	j	j	PROPN
fnp-3050	522	6	(	(	PUNCT
fnp-3050	522	7	2010	2010	NUM
fnp-3050	522	8	)	)	PUNCT
fnp-3050	522	9	prevalence	prevalence	NOUN
fnp-3050	522	10	of	of	ADP
fnp-3050	522	11	dementia	dementia	NOUN
fnp-3050	522	12	disorders	disorder	NOUN
fnp-3050	522	13	in	in	ADP
fnp-3050	522	14	the	the	DET
fnp-3050	522	15	oldest	oldest	ADV
fnp-3050	522	16	-	-	PUNCT
fnp-3050	522	17	old	old	ADJ
fnp-3050	522	18	:	:	PUNCT
fnp-3050	522	19	an	an	DET
fnp-3050	522	20	autopsy	autopsy	ADJ
fnp-3050	522	21	study	study	NOUN
fnp-3050	522	22	.	.	PUNCT
fnp-3050	523	1	acta	acta	PROPN
fnp-3050	523	2	neuropathol	neuropathol	PROPN
fnp-3050	523	3	119:421	119:421	PROPN
fnp-3050	523	4	-	-	PUNCT
fnp-3050	523	5	433	433	NUM
fnp-3050	523	6	4	4	NUM
fnp-3050	523	7	.	.	PUNCT
fnp-3050	523	8	fiest	fiest	PROPN
fnp-3050	523	9	km	km	PROPN
fnp-3050	523	10	,	,	PUNCT
fnp-3050	523	11	roberts	roberts	PROPN
fnp-3050	523	12	ji	ji	PROPN
fnp-3050	523	13	,	,	PUNCT
fnp-3050	523	14	maxwell	maxwell	PROPN
fnp-3050	523	15	cj	cj	PROPN
fnp-3050	523	16	,	,	PUNCT
fnp-3050	523	17	hogan	hogan	PROPN
fnp-3050	523	18	db	db	PROPN
fnp-3050	523	19	,	,	PUNCT
fnp-3050	523	20	smith	smith	PROPN
fnp-3050	523	21	ee	ee	PROPN
fnp-3050	523	22	,	,	PUNCT
fnp-3050	523	23	frolkis	frolkis	PROPN
fnp-3050	523	24	a	a	PRON
fnp-3050	523	25	,	,	PUNCT
fnp-3050	523	26	cohen	cohen	PROPN
fnp-3050	523	27	a	a	PROPN
fnp-3050	523	28	,	,	PUNCT
fnp-3050	523	29	kirk	kirk	PROPN
fnp-3050	523	30	a	a	PROPN
fnp-3050	523	31	,	,	PUNCT
fnp-3050	523	32	pearson	pearson	PROPN
fnp-3050	523	33	d	d	PROPN
fnp-3050	523	34	,	,	PUNCT
fnp-3050	523	35	pringsheim	pringsheim	PROPN
fnp-3050	523	36	t	t	PROPN
fnp-3050	523	37	,	,	PUNCT
fnp-3050	523	38	venegas	venegas	PROPN
fnp-3050	523	39	-	-	PUNCT
fnp-3050	523	40	torres	torre	VERB
fnp-3050	523	41	a	a	PRON
fnp-3050	523	42	,	,	PUNCT
fnp-3050	523	43	jetté	jetté	PROPN
fnp-3050	523	44	n	n	PROPN
fnp-3050	523	45	(	(	PUNCT
fnp-3050	523	46	2016	2016	NUM
fnp-3050	523	47	)	)	PUNCT
fnp-3050	523	48	the	the	DET
fnp-3050	523	49	prevalence	prevalence	NOUN
fnp-3050	523	50	and	and	CCONJ
fnp-3050	523	51	incidence	incidence	NOUN
fnp-3050	523	52	of	of	ADP
fnp-3050	523	53	dementia	dementia	NOUN
fnp-3050	523	54	due	due	ADP
fnp-3050	523	55	to	to	ADP
fnp-3050	523	56	alzheimer	alzheimer	PROPN
fnp-3050	523	57	's	's	PART
fnp-3050	523	58	disease	disease	NOUN
fnp-3050	523	59	:	:	PUNCT
fnp-3050	523	60	a	a	DET
fnp-3050	523	61	systematic	systematic	ADJ
fnp-3050	523	62	review	review	NOUN
fnp-3050	523	63	and	and	CCONJ
fnp-3050	523	64	meta	meta	ADJ
fnp-3050	523	65	-	-	PUNCT
fnp-3050	523	66	analysis	analysis	NOUN
fnp-3050	523	67	.	.	PUNCT
fnp-3050	524	1	canad	canad	PROPN
fnp-3050	524	2	j	j	PROPN
fnp-3050	524	3	neurol	neurol	PROPN
fnp-3050	524	4	sci	sci	PROPN
fnp-3050	524	5	43	43	NUM
fnp-3050	524	6	(	(	PUNCT
fnp-3050	524	7	suppl	suppl	PROPN
fnp-3050	524	8	s1):s51	s1):s51	NOUN
fnp-3050	524	9	-	-	PUNCT
fnp-3050	524	10	s82	s82	PROPN
fnp-3050	524	11	5	5	NUM
fnp-3050	524	12	.	.	PUNCT
fnp-3050	524	13	alzheimer's	alzheimer's	NOUN
fnp-3050	524	14	-	-	PUNCT
fnp-3050	524	15	association	association	NOUN
fnp-3050	524	16	(	(	PUNCT
fnp-3050	524	17	2020	2020	NUM
fnp-3050	524	18	)	)	PUNCT
fnp-3050	524	19	2020	2020	NUM
fnp-3050	524	20	alzheimer	alzheimer	PROPN
fnp-3050	524	21	's	's	PART
fnp-3050	524	22	disease	disease	NOUN
fnp-3050	524	23	facts	fact	NOUN
fnp-3050	524	24	and	and	CCONJ
fnp-3050	524	25	figures	figure	NOUN
fnp-3050	524	26	.	.	PUNCT
fnp-3050	525	1	alzheimers	alzheimers	PROPN
fnp-3050	525	2	dement	dement	PROPN
fnp-3050	525	3	online	online	PROPN
fnp-3050	525	4	mar	mar	PROPN
fnp-3050	525	5	10	10	NUM
fnp-3050	525	6	:	:	PUNCT
fnp-3050	525	7	doi	doi	NOUN
fnp-3050	525	8	:	:	PUNCT
fnp-3050	525	9	10.1002	10.1002	NUM
fnp-3050	525	10	/	/	SYM
fnp-3050	525	11	alz.12068	alz.12068	SYM
fnp-3050	525	12	6	6	NUM
fnp-3050	525	13	.	.	PUNCT
fnp-3050	526	1	prince	prince	PROPN
fnp-3050	526	2	m	m	PROPN
fnp-3050	526	3	,	,	PUNCT
fnp-3050	526	4	bryce	bryce	PROPN
fnp-3050	526	5	r	r	PROPN
fnp-3050	526	6	,	,	PUNCT
fnp-3050	526	7	albanese	albanese	ADJ
fnp-3050	526	8	e	e	NOUN
fnp-3050	526	9	,	,	PUNCT
fnp-3050	526	10	wimo	wimo	VERB
fnp-3050	526	11	a	a	PRON
fnp-3050	526	12	,	,	PUNCT
fnp-3050	526	13	ribeiro	ribeiro	PROPN
fnp-3050	526	14	w	w	PROPN
fnp-3050	526	15	,	,	PUNCT
fnp-3050	526	16	ferri	ferri	PROPN
fnp-3050	526	17	cp	cp	PROPN
fnp-3050	526	18	(	(	PUNCT
fnp-3050	526	19	2013	2013	NUM
fnp-3050	526	20	)	)	PUNCT
fnp-3050	526	21	the	the	DET
fnp-3050	526	22	global	global	ADJ
fnp-3050	526	23	prevalence	prevalence	NOUN
fnp-3050	526	24	of	of	ADP
fnp-3050	526	25	dementia	dementia	NOUN
fnp-3050	526	26	:	:	PUNCT
fnp-3050	526	27	a	a	DET
fnp-3050	526	28	systematic	systematic	ADJ
fnp-3050	526	29	review	review	NOUN
fnp-3050	526	30	and	and	CCONJ
fnp-3050	526	31	metaanalysis	metaanalysis	NOUN
fnp-3050	526	32	.	.	PUNCT
fnp-3050	527	1	alzheimers	alzheimers	PROPN
fnp-3050	527	2	dement	dement	PROPN
fnp-3050	527	3	9:63	9:63	PROPN
fnp-3050	527	4	-	-	SYM
fnp-3050	527	5	75	75	NUM
fnp-3050	527	6	e62	e62	NOUN
fnp-3050	527	7	7	7	NUM
fnp-3050	527	8	.	.	PUNCT
fnp-3050	528	1	long	long	PROPN
fnp-3050	528	2	jm	jm	PROPN
fnp-3050	528	3	,	,	PUNCT
fnp-3050	528	4	holtzman	holtzman	ADJ
fnp-3050	528	5	dm	dm	PROPN
fnp-3050	528	6	(	(	PUNCT
fnp-3050	528	7	2019	2019	NUM
fnp-3050	528	8	)	)	PUNCT
fnp-3050	528	9	alzheimer	alzheimer	NOUN
fnp-3050	528	10	disease	disease	NOUN
fnp-3050	528	11	:	:	PUNCT
fnp-3050	528	12	an	an	DET
fnp-3050	528	13	update	update	NOUN
fnp-3050	528	14	on	on	ADP
fnp-3050	528	15	pathobiology	pathobiology	NOUN
fnp-3050	528	16	and	and	CCONJ
fnp-3050	528	17	treatment	treatment	NOUN
fnp-3050	528	18	strategies	strategy	NOUN
fnp-3050	528	19	.	.	PUNCT
fnp-3050	529	1	cell	cell	NOUN
fnp-3050	529	2	179:312	179:312	PROPN
fnp-3050	529	3	-	-	PUNCT
fnp-3050	529	4	339	339	NUM
fnp-3050	529	5	8	8	NUM
fnp-3050	529	6	.	.	PUNCT
fnp-3050	530	1	ingelsson	ingelsson	PROPN
fnp-3050	530	2	m	m	PROPN
fnp-3050	530	3	,	,	PUNCT
fnp-3050	530	4	fukumoto	fukumoto	DET
fnp-3050	530	5	h	h	NOUN
fnp-3050	530	6	,	,	PUNCT
fnp-3050	530	7	newell	newell	PROPN
fnp-3050	530	8	kl	kl	PROPN
fnp-3050	530	9	,	,	PUNCT
fnp-3050	530	10	growdon	growdon	VERB
fnp-3050	530	11	jh	jh	PROPN
fnp-3050	530	12	,	,	PUNCT
fnp-3050	530	13	hedley	hedley	PROPN
fnp-3050	530	14	-	-	PUNCT
fnp-3050	530	15	whyte	whyte	PROPN
fnp-3050	530	16	et	et	PROPN
fnp-3050	530	17	,	,	PUNCT
fnp-3050	530	18	frosch	frosch	PROPN
fnp-3050	530	19	mp	mp	PROPN
fnp-3050	530	20	,	,	PUNCT
fnp-3050	530	21	albert	albert	PROPN
fnp-3050	530	22	ms	ms	PROPN
fnp-3050	530	23	,	,	PUNCT
fnp-3050	530	24	hyman	hyman	PROPN
fnp-3050	530	25	bt	bt	PROPN
fnp-3050	530	26	,	,	PUNCT
fnp-3050	530	27	irizarry	irizarry	ADJ
fnp-3050	530	28	mc	mc	PROPN
fnp-3050	530	29	(	(	PUNCT
fnp-3050	530	30	2004	2004	NUM
fnp-3050	530	31	)	)	PUNCT
fnp-3050	530	32	early	early	ADJ
fnp-3050	530	33	abeta	abeta	NOUN
fnp-3050	530	34	accumulation	accumulation	NOUN
fnp-3050	530	35	and	and	CCONJ
fnp-3050	530	36	progressive	progressive	ADJ
fnp-3050	530	37	synaptic	synaptic	ADJ
fnp-3050	530	38	loss	loss	NOUN
fnp-3050	530	39	,	,	PUNCT
fnp-3050	530	40	gliosis	gliosis	NOUN
fnp-3050	530	41	,	,	PUNCT
fnp-3050	530	42	and	and	CCONJ
fnp-3050	530	43	tangle	tangle	VERB
fnp-3050	530	44	formation	formation	NOUN
fnp-3050	530	45	in	in	ADP
fnp-3050	530	46	ad	ad	NOUN
fnp-3050	530	47	brain	brain	NOUN
fnp-3050	530	48	.	.	PUNCT
fnp-3050	531	1	neurology	neurology	NOUN
fnp-3050	531	2	62:925	62:925	PROPN
fnp-3050	531	3	-	-	SYM
fnp-3050	531	4	931	931	NUM
fnp-3050	531	5	9	9	NUM
fnp-3050	531	6	.	.	PUNCT
fnp-3050	532	1	keren	keren	PROPN
fnp-3050	532	2	-	-	PUNCT
fnp-3050	532	3	shaul	shaul	PROPN
fnp-3050	532	4	h	h	NOUN
fnp-3050	532	5	,	,	PUNCT
fnp-3050	532	6	spinrad	spinrad	X
fnp-3050	532	7	a	a	DET
fnp-3050	532	8	,	,	PUNCT
fnp-3050	532	9	weiner	weiner	NOUN
fnp-3050	532	10	a	a	PRON
fnp-3050	532	11	,	,	PUNCT
fnp-3050	532	12	matcovitch	matcovitch	NOUN
fnp-3050	532	13	-	-	PUNCT
fnp-3050	532	14	natan	natan	PROPN
fnp-3050	532	15	o	o	PROPN
fnp-3050	532	16	,	,	PUNCT
fnp-3050	532	17	dvir	dvir	PROPN
fnp-3050	532	18	-	-	PUNCT
fnp-3050	532	19	szternfeld	szternfeld	PROPN
fnp-3050	532	20	r	r	PROPN
fnp-3050	532	21	,	,	PUNCT
fnp-3050	532	22	ulland	ulland	PROPN
fnp-3050	532	23	tk	tk	PROPN
fnp-3050	532	24	,	,	PUNCT
fnp-3050	532	25	david	david	PROPN
fnp-3050	532	26	e	e	PROPN
fnp-3050	532	27	,	,	PUNCT
fnp-3050	532	28	baruch	baruch	ADJ
fnp-3050	532	29	k	k	NOUN
fnp-3050	532	30	,	,	PUNCT
fnp-3050	532	31	lara	lara	NOUN
fnp-3050	532	32	-	-	PUNCT
fnp-3050	532	33	astaiso	astaiso	NOUN
fnp-3050	532	34	d	d	NOUN
fnp-3050	532	35	,	,	PUNCT
fnp-3050	532	36	toth	toth	PROPN
fnp-3050	532	37	b	b	PROPN
fnp-3050	532	38	,	,	PUNCT
fnp-3050	532	39	itzkovitz	itzkovitz	PROPN
fnp-3050	532	40	s	s	PART
fnp-3050	532	41	,	,	PUNCT
fnp-3050	532	42	colonna	colonna	NOUN
fnp-3050	532	43	m	m	PROPN
fnp-3050	532	44	,	,	PUNCT
fnp-3050	532	45	schwartz	schwartz	PROPN
fnp-3050	532	46	m	m	PROPN
fnp-3050	532	47	,	,	PUNCT
fnp-3050	532	48	amit	amit	PROPN
fnp-3050	532	49	i	i	PRON
fnp-3050	532	50	(	(	PUNCT
fnp-3050	532	51	2017	2017	NUM
fnp-3050	532	52	)	)	PUNCT
fnp-3050	532	53	a	a	DET
fnp-3050	532	54	unique	unique	ADJ
fnp-3050	532	55	microglia	microglia	ADJ
fnp-3050	532	56	type	type	NOUN
fnp-3050	532	57	associated	associate	VERB
fnp-3050	532	58	with	with	ADP
fnp-3050	532	59	restricting	restrict	VERB
fnp-3050	532	60	development	development	NOUN
fnp-3050	532	61	of	of	ADP
fnp-3050	532	62	alzheimer	alzheimer	PROPN
fnp-3050	532	63	's	's	PART
fnp-3050	532	64	disease	disease	NOUN
fnp-3050	532	65	.	.	PUNCT
fnp-3050	533	1	cell	cell	NOUN
fnp-3050	533	2	169:1276	169:1276	NUM
fnp-3050	533	3	-	-	SYM
fnp-3050	533	4	1290	1290	NUM
fnp-3050	533	5	e1217	e1217	NUM
fnp-3050	533	6	10	10	NUM
fnp-3050	533	7	.	.	PUNCT
fnp-3050	534	1	monzio	monzio	PROPN
fnp-3050	534	2	compagnoni	compagnoni	PROPN
fnp-3050	534	3	g	g	PROPN
fnp-3050	534	4	,	,	PUNCT
fnp-3050	534	5	di	di	PROPN
fnp-3050	534	6	fonzo	fonzo	PROPN
fnp-3050	534	7	a	a	PROPN
fnp-3050	534	8	,	,	PUNCT
fnp-3050	534	9	corti	corti	PROPN
fnp-3050	534	10	s	s	PART
fnp-3050	534	11	,	,	PUNCT
fnp-3050	534	12	comi	comi	NOUN
fnp-3050	534	13	gp	gp	NOUN
fnp-3050	534	14	,	,	PUNCT
fnp-3050	534	15	bresolin	bresolin	NOUN
fnp-3050	534	16	n	n	NOUN
fnp-3050	534	17	,	,	PUNCT
fnp-3050	534	18	masliah	masliah	PROPN
fnp-3050	534	19	e	e	PROPN
fnp-3050	534	20	(	(	PUNCT
fnp-3050	534	21	2020	2020	NUM
fnp-3050	534	22	)	)	PUNCT
fnp-3050	534	23	the	the	DET
fnp-3050	534	24	role	role	NOUN
fnp-3050	534	25	of	of	ADP
fnp-3050	534	26	mitochondria	mitochondria	NOUN
fnp-3050	534	27	in	in	ADP
fnp-3050	534	28	neurodegenerative	neurodegenerative	ADJ
fnp-3050	534	29	diseases	disease	NOUN
fnp-3050	534	30	:	:	PUNCT
fnp-3050	534	31	the	the	DET
fnp-3050	534	32	lesson	lesson	NOUN
fnp-3050	534	33	from	from	ADP
fnp-3050	534	34	alzheimer	alzheimer	PROPN
fnp-3050	534	35	's	's	PART
fnp-3050	534	36	disease	disease	NOUN
fnp-3050	534	37	and	and	CCONJ
fnp-3050	534	38	parkinson	parkinson	NOUN
fnp-3050	534	39	's	's	PART
fnp-3050	534	40	disease	disease	NOUN
fnp-3050	534	41	.	.	PUNCT
fnp-3050	535	1	mol	mol	ADP
fnp-3050	535	2	neurobiol	neurobiol	PROPN
fnp-3050	535	3	57:2959	57:2959	NOUN
fnp-3050	535	4	-	-	SYM
fnp-3050	535	5	2980	2980	NUM
fnp-3050	535	6	11	11	NUM
fnp-3050	535	7	.	.	PUNCT
fnp-3050	536	1	gallardo	gallardo	PROPN
fnp-3050	536	2	g	g	PROPN
fnp-3050	536	3	,	,	PUNCT
fnp-3050	536	4	holtzman	holtzman	ADJ
fnp-3050	536	5	dm	dm	PROPN
fnp-3050	536	6	(	(	PUNCT
fnp-3050	536	7	2019	2019	NUM
fnp-3050	536	8	)	)	PUNCT
fnp-3050	536	9	amyloid	amyloid	NOUN
fnp-3050	536	10	-	-	PUNCT
fnp-3050	536	11	beta	beta	NOUN
fnp-3050	536	12	and	and	CCONJ
fnp-3050	536	13	tau	tau	PROPN
fnp-3050	536	14	at	at	ADP
fnp-3050	536	15	the	the	DET
fnp-3050	536	16	crossroads	crossroad	NOUN
fnp-3050	536	17	of	of	ADP
fnp-3050	536	18	alzheimer	alzheimer	PROPN
fnp-3050	536	19	's	's	PART
fnp-3050	536	20	disease	disease	NOUN
fnp-3050	536	21	.	.	PUNCT
fnp-3050	537	1	adv	adv	PROPN
fnp-3050	537	2	exp	exp	NOUN
fnp-3050	537	3	med	med	ADJ
fnp-3050	537	4	biol	biol	NOUN
fnp-3050	537	5	1184:187	1184:187	NUM
fnp-3050	537	6	-	-	SYM
fnp-3050	537	7	203	203	NUM
fnp-3050	537	8	12	12	NUM
fnp-3050	537	9	.	.	PUNCT
fnp-3050	538	1	kisler	kisler	PROPN
fnp-3050	538	2	k	k	PROPN
fnp-3050	538	3	,	,	PUNCT
fnp-3050	538	4	nelson	nelson	PROPN
fnp-3050	538	5	ar	ar	PROPN
fnp-3050	538	6	,	,	PUNCT
fnp-3050	538	7	montagne	montagne	PROPN
fnp-3050	538	8	a	a	PROPN
fnp-3050	538	9	,	,	PUNCT
fnp-3050	538	10	zlokovic	zlokovic	PROPN
fnp-3050	538	11	bv	bv	PROPN
fnp-3050	538	12	(	(	PUNCT
fnp-3050	538	13	2017	2017	NUM
fnp-3050	538	14	)	)	PUNCT
fnp-3050	538	15	cerebral	cerebral	ADJ
fnp-3050	538	16	blood	blood	NOUN
fnp-3050	538	17	flow	flow	NOUN
fnp-3050	538	18	regulation	regulation	NOUN
fnp-3050	538	19	and	and	CCONJ
fnp-3050	538	20	neurovascular	neurovascular	ADJ
fnp-3050	538	21	dysfunction	dysfunction	NOUN
fnp-3050	538	22	in	in	ADP
fnp-3050	538	23	alzheimer	alzheimer	PROPN
fnp-3050	538	24	disease	disease	PROPN
fnp-3050	538	25	.	.	PUNCT
fnp-3050	539	1	nat	nat	PROPN
fnp-3050	539	2	rev	rev	PROPN
fnp-3050	539	3	neurosci	neurosci	PROPN
fnp-3050	539	4	18:419	18:419	PROPN
fnp-3050	539	5	-	-	SYM
fnp-3050	539	6	434	434	NUM
fnp-3050	539	7	13	13	NUM
fnp-3050	539	8	.	.	PUNCT
fnp-3050	540	1	nation	nation	PROPN
fnp-3050	540	2	da	da	PROPN
fnp-3050	540	3	,	,	PUNCT
fnp-3050	540	4	sweeney	sweeney	PROPN
fnp-3050	540	5	md	md	PROPN
fnp-3050	540	6	,	,	PUNCT
fnp-3050	540	7	montagne	montagne	PROPN
fnp-3050	540	8	a	a	PROPN
fnp-3050	540	9	,	,	PUNCT
fnp-3050	540	10	sagare	sagare	PROPN
fnp-3050	540	11	ap	ap	PROPN
fnp-3050	540	12	,	,	PUNCT
fnp-3050	540	13	d'orazio	d'orazio	PROPN
fnp-3050	540	14	lm	lm	PROPN
fnp-3050	540	15	,	,	PUNCT
fnp-3050	540	16	pachicano	pachicano	PROPN
fnp-3050	540	17	m	m	PROPN
fnp-3050	540	18	,	,	PUNCT
fnp-3050	540	19	sepehrband	sepehrband	PROPN
fnp-3050	540	20	f	f	PROPN
fnp-3050	540	21	,	,	PUNCT
fnp-3050	540	22	nelson	nelson	PROPN
fnp-3050	540	23	ar	ar	PROPN
fnp-3050	540	24	,	,	PUNCT
fnp-3050	540	25	buennagel	buennagel	ADJ
fnp-3050	540	26	dp	dp	PROPN
fnp-3050	540	27	,	,	PUNCT
fnp-3050	540	28	harrington	harrington	PROPN
fnp-3050	540	29	mg	mg	PROPN
fnp-3050	540	30	,	,	PUNCT
fnp-3050	540	31	benzinger	benzinger	PROPN
fnp-3050	540	32	tls	tls	PROPN
fnp-3050	540	33	,	,	PUNCT
fnp-3050	540	34	fagan	fagan	PROPN
fnp-3050	540	35	am	be	AUX
fnp-3050	540	36	,	,	PUNCT
fnp-3050	540	37	ringman	ringman	PROPN
fnp-3050	540	38	jm	jm	PROPN
fnp-3050	540	39	,	,	PUNCT
fnp-3050	540	40	schneider	schneider	PROPN
fnp-3050	540	41	ls	ls	PROPN
fnp-3050	540	42	,	,	PUNCT
fnp-3050	540	43	morris	morris	PROPN
fnp-3050	540	44	jc	jc	PROPN
fnp-3050	540	45	,	,	PUNCT
fnp-3050	540	46	chui	chui	PROPN
fnp-3050	540	47	hc	hc	PROPN
fnp-3050	540	48	,	,	PUNCT
fnp-3050	540	49	law	law	NOUN
fnp-3050	540	50	m	m	PROPN
fnp-3050	540	51	,	,	PUNCT
fnp-3050	540	52	toga	toga	PROPN
fnp-3050	540	53	aw	aw	INTJ
fnp-3050	540	54	,	,	PUNCT
fnp-3050	540	55	zlokovic	zlokovic	PROPN
fnp-3050	540	56	bv	bv	PROPN
fnp-3050	540	57	(	(	PUNCT
fnp-3050	540	58	2019	2019	NUM
fnp-3050	540	59	)	)	PUNCT
fnp-3050	540	60	blood	blood	NOUN
fnp-3050	540	61	-	-	PUNCT
fnp-3050	540	62	brain	brain	NOUN
fnp-3050	540	63	barrier	barrier	NOUN
fnp-3050	540	64	breakdown	breakdown	NOUN
fnp-3050	540	65	is	be	AUX
fnp-3050	540	66	an	an	DET
fnp-3050	540	67	early	early	ADJ
fnp-3050	540	68	biomarker	biomarker	NOUN
fnp-3050	540	69	of	of	ADP
fnp-3050	540	70	human	human	ADJ
fnp-3050	540	71	cognitive	cognitive	ADJ
fnp-3050	540	72	dysfunction	dysfunction	NOUN
fnp-3050	540	73	.	.	PUNCT
fnp-3050	541	1	nat	nat	PROPN
fnp-3050	541	2	med	med	PROPN
fnp-3050	541	3	25:270	25:270	NUM
fnp-3050	541	4	-	-	SYM
fnp-3050	541	5	276	276	NUM
fnp-3050	541	6	14	14	NUM
fnp-3050	541	7	.	.	PUNCT
fnp-3050	542	1	carter	carter	PROPN
fnp-3050	542	2	sf	sf	PROPN
fnp-3050	542	3	,	,	PUNCT
fnp-3050	542	4	herholz	herholz	PROPN
fnp-3050	542	5	k	k	PROPN
fnp-3050	542	6	,	,	PUNCT
fnp-3050	542	7	rosa	rosa	PROPN
fnp-3050	542	8	-	-	PUNCT
fnp-3050	542	9	neto	neto	PROPN
fnp-3050	542	10	p	p	PROPN
fnp-3050	542	11	,	,	PUNCT
fnp-3050	542	12	pellerin	pellerin	NOUN
fnp-3050	542	13	l	l	PROPN
fnp-3050	542	14	,	,	PUNCT
fnp-3050	542	15	nordberg	nordberg	PROPN
fnp-3050	542	16	a	a	X
fnp-3050	542	17	,	,	PUNCT
fnp-3050	542	18	zimmer	zimmer	PROPN
fnp-3050	542	19	er	er	INTJ
fnp-3050	542	20	(	(	PUNCT
fnp-3050	542	21	2019	2019	NUM
fnp-3050	542	22	)	)	PUNCT
fnp-3050	542	23	astrocyte	astrocyte	NOUN
fnp-3050	542	24	biomarkers	biomarker	NOUN
fnp-3050	542	25	in	in	ADP
fnp-3050	542	26	alzheimer	alzheimer	PROPN
fnp-3050	542	27	's	's	PART
fnp-3050	542	28	disease	disease	NOUN
fnp-3050	542	29	.	.	PUNCT
fnp-3050	543	1	trends	trend	NOUN
fnp-3050	543	2	mol	mol	ADP
fnp-3050	543	3	med	med	ADJ
fnp-3050	543	4	25:77	25:77	NUM
fnp-3050	543	5	-	-	SYM
fnp-3050	543	6	95	95	NUM
fnp-3050	543	7	15	15	NUM
fnp-3050	543	8	.	.	PUNCT
fnp-3050	544	1	jack	jack	PROPN
fnp-3050	544	2	cr	cr	PROPN
fnp-3050	544	3	,	,	PUNCT
fnp-3050	544	4	jr	jr	PROPN
fnp-3050	544	5	.	.	PROPN
fnp-3050	544	6	,	,	PUNCT
fnp-3050	544	7	therneau	therneau	PROPN
fnp-3050	544	8	tm	tm	PROPN
fnp-3050	544	9	,	,	PUNCT
fnp-3050	544	10	weigand	weigand	PROPN
fnp-3050	544	11	sd	sd	NOUN
fnp-3050	544	12	,	,	PUNCT
fnp-3050	544	13	wiste	wiste	PROPN
fnp-3050	544	14	hj	hj	PROPN
fnp-3050	544	15	,	,	PUNCT
fnp-3050	544	16	knopman	knopman	NOUN
fnp-3050	544	17	ds	ds	PROPN
fnp-3050	544	18	,	,	PUNCT
fnp-3050	544	19	vemuri	vemuri	X
fnp-3050	544	20	p	p	X
fnp-3050	544	21	,	,	PUNCT
fnp-3050	544	22	lowe	lowe	PROPN
fnp-3050	544	23	vj	vj	PROPN
fnp-3050	544	24	,	,	PUNCT
fnp-3050	544	25	mielke	mielke	PROPN
fnp-3050	544	26	mm	mm	PROPN
fnp-3050	544	27	,	,	PUNCT
fnp-3050	544	28	roberts	roberts	PROPN
fnp-3050	544	29	ro	ro	PROPN
fnp-3050	544	30	,	,	PUNCT
fnp-3050	544	31	machulda	machulda	PROPN
fnp-3050	544	32	mm	mm	PROPN
fnp-3050	544	33	,	,	PUNCT
fnp-3050	544	34	graff	graff	PROPN
fnp-3050	544	35	-	-	PUNCT
fnp-3050	544	36	radford	radford	PROPN
fnp-3050	544	37	j	j	PROPN
fnp-3050	544	38	,	,	PUNCT
fnp-3050	544	39	jones	jones	PROPN
fnp-3050	545	1	dt	dt	PROPN
fnp-3050	545	2	,	,	PUNCT
fnp-3050	545	3	schwarz	schwarz	PROPN
fnp-3050	545	4	cg	cg	PROPN
fnp-3050	545	5	,	,	PUNCT
fnp-3050	545	6	gunter	gunter	PROPN
fnp-3050	545	7	jl	jl	PROPN
fnp-3050	545	8	,	,	PUNCT
fnp-3050	545	9	senjem	senjem	NOUN
fnp-3050	545	10	ml	ml	NOUN
fnp-3050	545	11	,	,	PUNCT
fnp-3050	545	12	rocca	rocca	PROPN
fnp-3050	545	13	wa	wa	PROPN
fnp-3050	545	14	,	,	PUNCT
fnp-3050	545	15	petersen	petersen	PROPN
fnp-3050	545	16	rc	rc	PROPN
fnp-3050	545	17	(	(	PUNCT
fnp-3050	545	18	2019	2019	NUM
fnp-3050	545	19	)	)	PUNCT
fnp-3050	545	20	prevalence	prevalence	NOUN
fnp-3050	545	21	of	of	ADP
fnp-3050	545	22	biologically	biologically	ADV
fnp-3050	545	23	vs	vs	ADP
fnp-3050	545	24	clinically	clinically	ADV
fnp-3050	545	25	defined	define	VERB
fnp-3050	545	26	alzheimer	alzheimer	PROPN
fnp-3050	545	27	spectrum	spectrum	NOUN
fnp-3050	545	28	entities	entity	NOUN
fnp-3050	545	29	using	use	VERB
fnp-3050	545	30	the	the	DET
fnp-3050	545	31	national	national	PROPN
fnp-3050	545	32	institute	institute	NOUN
fnp-3050	545	33	on	on	ADP
fnp-3050	545	34	aging	age	VERB
fnp-3050	545	35	-	-	PUNCT
fnp-3050	545	36	alzheimer	alzheimer	NOUN
fnp-3050	545	37	's	's	PART
fnp-3050	545	38	association	association	NOUN
fnp-3050	545	39	research	research	NOUN
fnp-3050	545	40	framework	framework	NOUN
fnp-3050	545	41	.	.	PUNCT
fnp-3050	546	1	jama	jama	PROPN
fnp-3050	546	2	neurol	neurol	PROPN
fnp-3050	546	3	76:1174	76:1174	PROPN
fnp-3050	546	4	-	-	SYM
fnp-3050	546	5	1183	1183	NUM
fnp-3050	546	6	16	16	NUM
fnp-3050	546	7	.	.	PUNCT
fnp-3050	547	1	ferreira	ferreira	PROPN
fnp-3050	547	2	d	d	PROPN
fnp-3050	547	3	,	,	PUNCT
fnp-3050	547	4	nordberg	nordberg	ADV
fnp-3050	547	5	a	a	PRON
fnp-3050	547	6	,	,	PUNCT
fnp-3050	547	7	westman	westman	NOUN
fnp-3050	547	8	e	e	X
fnp-3050	547	9	(	(	PUNCT
fnp-3050	547	10	2020	2020	NUM
fnp-3050	547	11	)	)	PUNCT
fnp-3050	547	12	biological	biological	ADJ
fnp-3050	547	13	subtypes	subtype	NOUN
fnp-3050	547	14	of	of	ADP
fnp-3050	547	15	alzheimer	alzheimer	PROPN
fnp-3050	547	16	disease	disease	PROPN
fnp-3050	547	17	:	:	PUNCT
fnp-3050	547	18	a	a	DET
fnp-3050	547	19	systematic	systematic	ADJ
fnp-3050	547	20	review	review	NOUN
fnp-3050	547	21	and	and	CCONJ
fnp-3050	547	22	meta	meta	ADJ
fnp-3050	547	23	-	-	PUNCT
fnp-3050	547	24	analysis	analysis	NOUN
fnp-3050	547	25	.	.	PUNCT
fnp-3050	548	1	neurology	neurology	NOUN
fnp-3050	548	2	94:436	94:436	PROPN
fnp-3050	548	3	-	-	PUNCT
fnp-3050	548	4	448	448	NUM
fnp-3050	548	5	17	17	NUM
fnp-3050	548	6	.	.	PUNCT
fnp-3050	549	1	montine	montine	PROPN
fnp-3050	549	2	tj	tj	PROPN
fnp-3050	549	3	,	,	PUNCT
fnp-3050	549	4	phelps	phelps	PROPN
fnp-3050	549	5	ch	ch	PROPN
fnp-3050	549	6	,	,	PUNCT
fnp-3050	549	7	beach	beach	PROPN
fnp-3050	549	8	tg	tg	PROPN
fnp-3050	549	9	,	,	PUNCT
fnp-3050	549	10	bigio	bigio	NOUN
fnp-3050	549	11	eh	eh	INTJ
fnp-3050	549	12	,	,	PUNCT
fnp-3050	549	13	cairns	cairns	PROPN
fnp-3050	549	14	nj	nj	PROPN
fnp-3050	549	15	,	,	PUNCT
fnp-3050	549	16	dickson	dickson	PROPN
fnp-3050	549	17	dw	dw	PROPN
fnp-3050	549	18	,	,	PUNCT
fnp-3050	549	19	duyckaerts	duyckaerts	PROPN
fnp-3050	549	20	c	c	PROPN
fnp-3050	549	21	,	,	PUNCT
fnp-3050	549	22	frosch	frosch	PROPN
fnp-3050	549	23	mp	mp	PROPN
fnp-3050	549	24	,	,	PUNCT
fnp-3050	549	25	masliah	masliah	PROPN
fnp-3050	549	26	e	e	PROPN
fnp-3050	549	27	,	,	PUNCT
fnp-3050	549	28	mirra	mirra	PROPN
fnp-3050	549	29	ss	ss	PROPN
fnp-3050	549	30	,	,	PUNCT
fnp-3050	549	31	nelson	nelson	PROPN
fnp-3050	549	32	pt	pt	PROPN
fnp-3050	549	33	,	,	PUNCT
fnp-3050	549	34	schneider	schneider	PROPN
fnp-3050	549	35	ja	ja	PROPN
fnp-3050	549	36	,	,	PUNCT
fnp-3050	549	37	thal	thal	PROPN
fnp-3050	549	38	dr	dr	PROPN
fnp-3050	549	39	,	,	PUNCT
fnp-3050	549	40	trojanowski	trojanowski	PROPN
fnp-3050	549	41	jq	jq	PROPN
fnp-3050	549	42	,	,	PUNCT
fnp-3050	549	43	vinters	vinters	PROPN
fnp-3050	549	44	hv	hv	PROPN
fnp-3050	549	45	,	,	PUNCT
fnp-3050	549	46	hyman	hyman	PROPN
fnp-3050	549	47	bt	bt	PROPN
fnp-3050	549	48	(	(	PUNCT
fnp-3050	549	49	2012	2012	NUM
fnp-3050	549	50	)	)	PUNCT
fnp-3050	549	51	national	national	PROPN
fnp-3050	549	52	institute	institute	NOUN
fnp-3050	549	53	on	on	ADP
fnp-3050	549	54	aging	age	VERB
fnp-3050	549	55	-	-	PUNCT
fnp-3050	549	56	alzheimer	alzheimer	NOUN
fnp-3050	549	57	's	's	PART
fnp-3050	549	58	association	association	NOUN
fnp-3050	549	59	guidelines	guideline	NOUN
fnp-3050	549	60	for	for	ADP
fnp-3050	549	61	the	the	DET
fnp-3050	549	62	neuropathologic	neuropathologic	ADJ
fnp-3050	549	63	assessment	assessment	NOUN
fnp-3050	549	64	of	of	ADP
fnp-3050	549	65	alzheimer	alzheimer	PROPN
fnp-3050	549	66	's	's	PART
fnp-3050	549	67	disease	disease	NOUN
fnp-3050	549	68	:	:	PUNCT
fnp-3050	549	69	a	a	DET
fnp-3050	549	70	practical	practical	ADJ
fnp-3050	549	71	approach	approach	NOUN
fnp-3050	549	72	.	.	PUNCT
fnp-3050	550	1	acta	acta	PROPN
fnp-3050	550	2	neuropathol	neuropathol	PROPN
fnp-3050	550	3	123:1	123:1	NUM
fnp-3050	550	4	-	-	SYM
fnp-3050	550	5	11	11	NUM
fnp-3050	550	6	18	18	NUM
fnp-3050	550	7	.	.	PUNCT
fnp-3050	551	1	braak	braak	PROPN
fnp-3050	551	2	h	h	PROPN
fnp-3050	551	3	,	,	PUNCT
fnp-3050	551	4	braak	braak	PROPN
fnp-3050	551	5	e	e	X
fnp-3050	551	6	(	(	PUNCT
fnp-3050	551	7	1991	1991	NUM
fnp-3050	551	8	)	)	PUNCT
fnp-3050	551	9	neuropathological	neuropathological	NOUN
fnp-3050	551	10	stageing	stageing	NOUN
fnp-3050	551	11	of	of	ADP
fnp-3050	551	12	alzheimer	alzheimer	NOUN
fnp-3050	551	13	-	-	PUNCT
fnp-3050	551	14	related	relate	VERB
fnp-3050	551	15	changes	change	NOUN
fnp-3050	551	16	.	.	PUNCT
fnp-3050	552	1	acta	acta	PROPN
fnp-3050	552	2	neuropathol	neuropathol	PROPN
fnp-3050	552	3	82:239	82:239	NUM
fnp-3050	552	4	-	-	SYM
fnp-3050	552	5	259	259	NUM
fnp-3050	552	6	19	19	NUM
fnp-3050	552	7	.	.	PUNCT
fnp-3050	553	1	fornari	fornari	PROPN
fnp-3050	553	2	s	s	PROPN
fnp-3050	553	3	,	,	PUNCT
fnp-3050	553	4	schäfer	schäfer	VERB
fnp-3050	553	5	a	a	DET
fnp-3050	553	6	,	,	PUNCT
fnp-3050	553	7	jucker	jucker	PROPN
fnp-3050	553	8	m	m	PROPN
fnp-3050	553	9	,	,	PUNCT
fnp-3050	553	10	goriely	goriely	ADV
fnp-3050	553	11	a	a	PRON
fnp-3050	553	12	,	,	PUNCT
fnp-3050	553	13	kuhl	kuhl	PROPN
fnp-3050	553	14	e	e	X
fnp-3050	553	15	(	(	PUNCT
fnp-3050	553	16	2019	2019	NUM
fnp-3050	553	17	)	)	PUNCT
fnp-3050	553	18	prion	prion	NOUN
fnp-3050	553	19	-	-	PUNCT
fnp-3050	553	20	like	like	ADJ
fnp-3050	553	21	spreading	spreading	NOUN
fnp-3050	553	22	of	of	ADP
fnp-3050	553	23	alzheimer	alzheimer	PROPN
fnp-3050	553	24	's	's	PART
fnp-3050	553	25	disease	disease	NOUN
fnp-3050	553	26	within	within	ADP
fnp-3050	553	27	the	the	DET
fnp-3050	553	28	brain	brain	NOUN
fnp-3050	553	29	's	's	PART
fnp-3050	553	30	connectome	connectome	NOUN
fnp-3050	553	31	.	.	PUNCT
fnp-3050	554	1	j	j	PROPN
fnp-3050	554	2	r	r	NOUN
fnp-3050	554	3	soc	soc	NOUN
fnp-3050	554	4	interface	interface	NOUN
fnp-3050	554	5	16:20190356	16:20190356	NUM
fnp-3050	554	6	20	20	NUM
fnp-3050	554	7	.	.	PUNCT
fnp-3050	554	8	mattsson	mattsson	PROPN
fnp-3050	554	9	n	n	CCONJ
fnp-3050	554	10	,	,	PUNCT
fnp-3050	554	11	schott	schott	PROPN
fnp-3050	554	12	jm	jm	PROPN
fnp-3050	554	13	,	,	PUNCT
fnp-3050	554	14	hardy	hardy	PROPN
fnp-3050	554	15	j	j	PROPN
fnp-3050	554	16	,	,	PUNCT
fnp-3050	554	17	turner	turner	PROPN
fnp-3050	554	18	mr	mr	PROPN
fnp-3050	554	19	,	,	PUNCT
fnp-3050	554	20	zetterberg	zetterberg	PROPN
fnp-3050	554	21	h	h	PROPN
fnp-3050	554	22	(	(	PUNCT
fnp-3050	554	23	2016	2016	NUM
fnp-3050	554	24	)	)	PUNCT
fnp-3050	554	25	selective	selective	ADJ
fnp-3050	554	26	vulnerability	vulnerability	NOUN
fnp-3050	554	27	in	in	ADP
fnp-3050	554	28	neurodegeneration	neurodegeneration	NOUN
fnp-3050	554	29	:	:	PUNCT
fnp-3050	554	30	insights	insight	NOUN
fnp-3050	554	31	from	from	ADP
fnp-3050	554	32	clinical	clinical	ADJ
fnp-3050	554	33	variants	variant	NOUN
fnp-3050	554	34	of	of	ADP
fnp-3050	554	35	alzheimer	alzheimer	PROPN
fnp-3050	554	36	's	's	PART
fnp-3050	554	37	disease	disease	NOUN
fnp-3050	554	38	.	.	PUNCT
fnp-3050	555	1	j	j	PROPN
fnp-3050	555	2	neurol	neurol	PROPN
fnp-3050	555	3	neurosurg	neurosurg	PROPN
fnp-3050	555	4	psychiatry	psychiatry	PROPN
fnp-3050	555	5	87:1000	87:1000	NUM
fnp-3050	555	6	-	-	SYM
fnp-3050	555	7	1004	1004	NUM
fnp-3050	555	8	21	21	NUM
fnp-3050	555	9	.	.	PUNCT
fnp-3050	556	1	mrdjen	mrdjen	PROPN
fnp-3050	556	2	d	d	PROPN
fnp-3050	556	3	,	,	PUNCT
fnp-3050	556	4	fox	fox	PROPN
fnp-3050	556	5	ej	ej	PROPN
fnp-3050	556	6	,	,	PUNCT
fnp-3050	556	7	bukhari	bukhari	PROPN
fnp-3050	556	8	sa	sa	PROPN
fnp-3050	556	9	,	,	PUNCT
fnp-3050	556	10	montine	montine	PROPN
fnp-3050	556	11	ks	ks	PROPN
fnp-3050	556	12	,	,	PUNCT
fnp-3050	556	13	bendall	bendall	PROPN
fnp-3050	556	14	sc	sc	PROPN
fnp-3050	556	15	,	,	PUNCT
fnp-3050	556	16	montine	montine	PROPN
fnp-3050	556	17	tj	tj	PROPN
fnp-3050	556	18	(	(	PUNCT
fnp-3050	556	19	2019	2019	NUM
fnp-3050	556	20	)	)	PUNCT
fnp-3050	556	21	the	the	DET
fnp-3050	556	22	basis	basis	NOUN
fnp-3050	556	23	of	of	ADP
fnp-3050	556	24	cellular	cellular	ADJ
fnp-3050	556	25	and	and	CCONJ
fnp-3050	556	26	regional	regional	ADJ
fnp-3050	556	27	vulnerability	vulnerability	NOUN
fnp-3050	556	28	in	in	ADP
fnp-3050	556	29	alzheimer	alzheimer	PROPN
fnp-3050	556	30	's	's	PART
fnp-3050	556	31	disease	disease	NOUN
fnp-3050	556	32	.	.	PUNCT
fnp-3050	557	1	acta	acta	PROPN
fnp-3050	557	2	neuropathol	neuropathol	PROPN
fnp-3050	557	3	138:729	138:729	PROPN
fnp-3050	557	4	-	-	PUNCT
fnp-3050	557	5	749	749	NUM
fnp-3050	557	6	22	22	NUM
fnp-3050	557	7	.	.	PUNCT
fnp-3050	558	1	grothe	grothe	PROPN
fnp-3050	558	2	mj	mj	PROPN
fnp-3050	558	3	,	,	PUNCT
fnp-3050	558	4	sepulcre	sepulcre	PROPN
fnp-3050	558	5	j	j	PROPN
fnp-3050	558	6	,	,	PUNCT
fnp-3050	558	7	gonzalez	gonzalez	PROPN
fnp-3050	558	8	-	-	PUNCT
fnp-3050	558	9	escamilla	escamilla	NOUN
fnp-3050	558	10	g	g	NOUN
fnp-3050	558	11	,	,	PUNCT
fnp-3050	558	12	jelistratova	jelistratova	VERB
fnp-3050	558	13	i	i	PRON
fnp-3050	558	14	,	,	PUNCT
fnp-3050	558	15	schöll	schöll	PROPN
fnp-3050	558	16	m	m	PROPN
fnp-3050	558	17	,	,	PUNCT
fnp-3050	558	18	hansson	hansson	PROPN
fnp-3050	558	19	o	o	NOUN
fnp-3050	558	20	,	,	PUNCT
fnp-3050	558	21	teipel	teipel	PROPN
fnp-3050	558	22	sj	sj	NOUN
fnp-3050	558	23	(	(	PUNCT
fnp-3050	558	24	2018	2018	NUM
fnp-3050	558	25	)	)	PUNCT
fnp-3050	558	26	molecular	molecular	ADJ
fnp-3050	558	27	properties	property	NOUN
fnp-3050	558	28	underlying	underlie	VERB
fnp-3050	558	29	regional	regional	ADJ
fnp-3050	558	30	vulnerability	vulnerability	NOUN
fnp-3050	558	31	to	to	ADP
fnp-3050	558	32	alzheimer	alzheimer	PROPN
fnp-3050	558	33	's	's	PART
fnp-3050	558	34	disease	disease	NOUN
fnp-3050	558	35	pathology	pathology	NOUN
fnp-3050	558	36	.	.	PUNCT
fnp-3050	559	1	brain	brain	PROPN
fnp-3050	559	2	141:2755	141:2755	NUM
fnp-3050	559	3	-	-	SYM
fnp-3050	559	4	2771	2771	NUM
fnp-3050	559	5	23	23	NUM
fnp-3050	559	6	.	.	PUNCT
fnp-3050	560	1	wang	wang	PROPN
fnp-3050	560	2	zt	zt	PROPN
fnp-3050	560	3	,	,	PUNCT
fnp-3050	560	4	zhang	zhang	PROPN
fnp-3050	560	5	c	c	PROPN
fnp-3050	560	6	,	,	PUNCT
fnp-3050	560	7	wang	wang	PROPN
fnp-3050	560	8	yj	yj	PROPN
fnp-3050	560	9	,	,	PUNCT
fnp-3050	560	10	dong	dong	PROPN
fnp-3050	560	11	q	q	PROPN
fnp-3050	560	12	,	,	PUNCT
fnp-3050	560	13	tan	tan	PROPN
fnp-3050	560	14	l	l	NOUN
fnp-3050	560	15	,	,	PUNCT
fnp-3050	560	16	yu	yu	PROPN
fnp-3050	560	17	jt	jt	PROPN
fnp-3050	560	18	(	(	PUNCT
fnp-3050	560	19	2020	2020	NUM
fnp-3050	560	20	)	)	PUNCT
fnp-3050	560	21	selective	selective	ADJ
fnp-3050	560	22	neuronal	neuronal	ADJ
fnp-3050	560	23	vulnerability	vulnerability	NOUN
fnp-3050	560	24	in	in	ADP
fnp-3050	560	25	alzheimer	alzheimer	PROPN
fnp-3050	560	26	's	's	PART
fnp-3050	560	27	disease	disease	NOUN
fnp-3050	560	28	.	.	PUNCT
fnp-3050	561	1	ageing	age	VERB
fnp-3050	561	2	res	re	NOUN
fnp-3050	561	3	rev	rev	VERB
fnp-3050	561	4	62:101114	62:101114	PROPN
fnp-3050	561	5	24	24	NUM
fnp-3050	561	6	.	.	PUNCT
fnp-3050	562	1	acosta	acosta	PROPN
fnp-3050	562	2	d	d	PROPN
fnp-3050	562	3	,	,	PUNCT
fnp-3050	562	4	powell	powell	PROPN
fnp-3050	562	5	f	f	PROPN
fnp-3050	562	6	,	,	PUNCT
fnp-3050	562	7	zhao	zhao	PROPN
fnp-3050	562	8	y	y	PROPN
fnp-3050	562	9	,	,	PUNCT
fnp-3050	562	10	raj	raj	PROPN
fnp-3050	562	11	a	a	DET
fnp-3050	562	12	(	(	PUNCT
fnp-3050	562	13	2018	2018	NUM
fnp-3050	562	14	)	)	PUNCT
fnp-3050	562	15	regional	regional	ADJ
fnp-3050	562	16	vulnerability	vulnerability	NOUN
fnp-3050	562	17	in	in	ADP
fnp-3050	562	18	alzheimer	alzheimer	PROPN
fnp-3050	562	19	's	's	PART
fnp-3050	562	20	disease	disease	NOUN
fnp-3050	562	21	:	:	PUNCT
fnp-3050	562	22	the	the	DET
fnp-3050	562	23	role	role	NOUN
fnp-3050	562	24	of	of	ADP
fnp-3050	562	25	cell	cell	NOUN
fnp-3050	562	26	-	-	PUNCT
fnp-3050	562	27	autonomous	autonomous	ADJ
fnp-3050	562	28	and	and	CCONJ
fnp-3050	562	29	transneuronal	transneuronal	ADJ
fnp-3050	562	30	processes	process	NOUN
fnp-3050	562	31	.	.	PUNCT
fnp-3050	563	1	alzheimers	alzheimers	PROPN
fnp-3050	563	2	dement	dement	PROPN
fnp-3050	563	3	14:797	14:797	PROPN
fnp-3050	563	4	-	-	SYM
fnp-3050	563	5	810	810	NUM
fnp-3050	563	6	25	25	NUM
fnp-3050	563	7	.	.	PUNCT
fnp-3050	564	1	roussarie	roussarie	PROPN
fnp-3050	564	2	jp	jp	PROPN
fnp-3050	564	3	,	,	PUNCT
fnp-3050	564	4	yao	yao	PROPN
fnp-3050	564	5	v	v	NOUN
fnp-3050	564	6	,	,	PUNCT
fnp-3050	564	7	rodriguez	rodriguez	NOUN
fnp-3050	564	8	-	-	PUNCT
fnp-3050	564	9	rodriguez	rodriguez	NOUN
fnp-3050	564	10	p	p	NOUN
fnp-3050	564	11	,	,	PUNCT
fnp-3050	564	12	oughtred	oughtre	VERB
fnp-3050	564	13	r	r	NOUN
fnp-3050	564	14	,	,	PUNCT
fnp-3050	564	15	rust	rust	PROPN
fnp-3050	564	16	j	j	PROPN
fnp-3050	564	17	,	,	PUNCT
fnp-3050	564	18	plautz	plautz	ADJ
fnp-3050	564	19	z	z	PROPN
fnp-3050	564	20	,	,	PUNCT
fnp-3050	564	21	kasturia	kasturia	PROPN
fnp-3050	564	22	s	s	PROPN
fnp-3050	564	23	,	,	PUNCT
fnp-3050	564	24	albornoz	albornoz	PROPN
fnp-3050	564	25	c	c	PROPN
fnp-3050	564	26	,	,	PUNCT
fnp-3050	564	27	wang	wang	PROPN
fnp-3050	564	28	w	w	PROPN
fnp-3050	564	29	,	,	PUNCT
fnp-3050	564	30	schmidt	schmidt	PROPN
fnp-3050	564	31	ef	ef	PROPN
fnp-3050	564	32	,	,	PUNCT
fnp-3050	564	33	dannenfelser	dannenfelser	NOUN
fnp-3050	564	34	r	r	NOUN
fnp-3050	564	35	,	,	PUNCT
fnp-3050	564	36	tadych	tadych	NOUN
fnp-3050	564	37	a	a	PRON
fnp-3050	564	38	,	,	PUNCT
fnp-3050	564	39	brichta	brichta	PROPN
fnp-3050	564	40	l	l	PROPN
fnp-3050	564	41	,	,	PUNCT
fnp-3050	564	42	barnea	barnea	NOUN
fnp-3050	564	43	-	-	PUNCT
fnp-3050	564	44	cramer	cramer	PROPN
fnp-3050	564	45	a	a	PROPN
fnp-3050	564	46	,	,	PUNCT
fnp-3050	564	47	heintz	heintz	PROPN
fnp-3050	564	48	n	n	CCONJ
fnp-3050	564	49	,	,	PUNCT
fnp-3050	564	50	hof	hof	PROPN
fnp-3050	564	51	pr	pr	PROPN
fnp-3050	564	52	,	,	PUNCT
fnp-3050	564	53	heiman	heiman	NOUN
fnp-3050	564	54	m	m	PROPN
fnp-3050	564	55	,	,	PUNCT
fnp-3050	564	56	dolinski	dolinski	VERB
fnp-3050	564	57	k	k	NOUN
fnp-3050	564	58	,	,	PUNCT
fnp-3050	564	59	flajolet	flajolet	NOUN
fnp-3050	564	60	m	m	PROPN
fnp-3050	564	61	,	,	PUNCT
fnp-3050	564	62	troyanskaya	troyanskaya	PROPN
fnp-3050	564	63	og	og	PROPN
fnp-3050	564	64	,	,	PUNCT
fnp-3050	564	65	greengard	greengard	ADJ
fnp-3050	564	66	p	p	X
fnp-3050	564	67	(	(	PUNCT
fnp-3050	564	68	2020	2020	NUM
fnp-3050	564	69	)	)	PUNCT
fnp-3050	564	70	selective	selective	ADJ
fnp-3050	564	71	neuronal	neuronal	ADJ
fnp-3050	564	72	vulnerability	vulnerability	NOUN
fnp-3050	564	73	in	in	ADP
fnp-3050	564	74	alzheimer	alzheimer	PROPN
fnp-3050	564	75	's	's	PART
fnp-3050	564	76	disease	disease	NOUN
fnp-3050	564	77	:	:	PUNCT
fnp-3050	564	78	a	a	DET
fnp-3050	564	79	network	network	NOUN
fnp-3050	564	80	-	-	PUNCT
fnp-3050	564	81	based	base	VERB
fnp-3050	564	82	analysis	analysis	NOUN
fnp-3050	564	83	.	.	PUNCT
fnp-3050	565	1	neuron	neuron	PROPN
fnp-3050	565	2	107	107	NUM
fnp-3050	565	3	:	:	PUNCT
fnp-3050	565	4	p821	p821	NUM
fnp-3050	565	5	-	-	SYM
fnp-3050	565	6	835.e812	835.e812	NUM
fnp-3050	565	7	26	26	NUM
fnp-3050	565	8	.	.	PUNCT
fnp-3050	566	1	warren	warren	PROPN
fnp-3050	566	2	jd	jd	PROPN
fnp-3050	566	3	,	,	PUNCT
fnp-3050	566	4	fletcher	fletcher	PROPN
fnp-3050	566	5	pd	pd	PROPN
fnp-3050	566	6	,	,	PUNCT
fnp-3050	566	7	golden	golden	ADJ
fnp-3050	566	8	hl	hl	NOUN
fnp-3050	566	9	(	(	PUNCT
fnp-3050	566	10	2012	2012	NUM
fnp-3050	566	11	)	)	PUNCT
fnp-3050	566	12	the	the	DET
fnp-3050	566	13	paradox	paradox	NOUN
fnp-3050	566	14	of	of	ADP
fnp-3050	566	15	syndromic	syndromic	ADJ
fnp-3050	566	16	diversity	diversity	NOUN
fnp-3050	566	17	in	in	ADP
fnp-3050	566	18	alzheimer	alzheimer	PROPN
fnp-3050	566	19	disease	disease	PROPN
fnp-3050	566	20	.	.	PUNCT
fnp-3050	567	1	nat	nat	PROPN
fnp-3050	567	2	rev	rev	VERB
fnp-3050	567	3	neurol	neurol	PROPN
fnp-3050	567	4	8:451	8:451	NUM
fnp-3050	567	5	-	-	SYM
fnp-3050	567	6	464	464	NUM
fnp-3050	567	7	27	27	NUM
fnp-3050	567	8	.	.	PUNCT
fnp-3050	568	1	jellinger	jellinger	PROPN
fnp-3050	568	2	ka	ka	PROPN
fnp-3050	568	3	(	(	PUNCT
fnp-3050	568	4	2020	2020	NUM
fnp-3050	568	5	)	)	PUNCT
fnp-3050	568	6	towards	towards	ADP
fnp-3050	568	7	a	a	DET
fnp-3050	568	8	biological	biological	ADJ
fnp-3050	568	9	definition	definition	NOUN
fnp-3050	568	10	of	of	ADP
fnp-3050	568	11	alzheimer	alzheimer	PROPN
fnp-3050	568	12	disease	disease	PROPN
fnp-3050	568	13	.	.	PUNCT
fnp-3050	569	1	int	int	PROPN
fnp-3050	569	2	j	j	PROPN
fnp-3050	569	3	neurol	neurol	NOUN
fnp-3050	569	4	neurother	neurother	PROPN
fnp-3050	569	5	7:095	7:095	NUM
fnp-3050	569	6	;	;	PUNCT
fnp-3050	569	7	doi	doi	X
fnp-3050	569	8	010.23937/22378	010.23937/22378	PROPN
fnp-3050	569	9	-	-	PUNCT
fnp-3050	569	10	23001/1410095	23001/1410095	NUM
fnp-3050	569	11	28	28	NUM
fnp-3050	569	12	.	.	PUNCT
fnp-3050	570	1	zhou	zhou	PROPN
fnp-3050	570	2	j	j	PROPN
fnp-3050	570	3	,	,	PUNCT
fnp-3050	570	4	greicius	greicius	PROPN
fnp-3050	570	5	md	md	PROPN
fnp-3050	570	6	,	,	PUNCT
fnp-3050	570	7	gennatas	gennata	NOUN
fnp-3050	570	8	ed	ed	NOUN
fnp-3050	570	9	,	,	PUNCT
fnp-3050	570	10	growdon	growdon	VERB
fnp-3050	570	11	me	i	PRON
fnp-3050	570	12	,	,	PUNCT
fnp-3050	570	13	jang	jang	PROPN
fnp-3050	570	14	jy	jy	PROPN
fnp-3050	570	15	,	,	PUNCT
fnp-3050	570	16	rabinovici	rabinovici	PROPN
fnp-3050	570	17	gd	gd	PROPN
fnp-3050	570	18	,	,	PUNCT
fnp-3050	570	19	kramer	kramer	PROPN
fnp-3050	570	20	jh	jh	PROPN
fnp-3050	570	21	,	,	PUNCT
fnp-3050	570	22	weiner	weiner	NOUN
fnp-3050	570	23	m	m	PROPN
fnp-3050	570	24	,	,	PUNCT
fnp-3050	570	25	miller	miller	PROPN
fnp-3050	570	26	bl	bl	PROPN
fnp-3050	570	27	,	,	PUNCT
fnp-3050	570	28	seeley	seeley	PROPN
fnp-3050	570	29	ww	ww	PROPN
fnp-3050	570	30	(	(	PUNCT
fnp-3050	570	31	2010	2010	NUM
fnp-3050	570	32	)	)	PUNCT
fnp-3050	570	33	divergent	divergent	ADJ
fnp-3050	570	34	network	network	NOUN
fnp-3050	570	35	connectivity	connectivity	NOUN
fnp-3050	570	36	changes	change	NOUN
fnp-3050	570	37	in	in	ADP
fnp-3050	570	38	behavioural	behavioural	ADJ
fnp-3050	570	39	variant	variant	ADJ
fnp-3050	570	40	frontotemporal	frontotemporal	ADJ
fnp-3050	570	41	dementia	dementia	NOUN
fnp-3050	570	42	and	and	CCONJ
fnp-3050	570	43	alzheimer	alzheimer	PROPN
fnp-3050	570	44	's	's	PART
fnp-3050	570	45	disease	disease	NOUN
fnp-3050	570	46	.	.	PUNCT
fnp-3050	571	1	brain	brain	NOUN
fnp-3050	571	2	133:1352	133:1352	NUM
fnp-3050	571	3	-	-	SYM
fnp-3050	571	4	1367	1367	NUM
fnp-3050	571	5	29	29	NUM
fnp-3050	571	6	.	.	PUNCT
fnp-3050	572	1	piguet	piguet	PROPN
fnp-3050	572	2	o	o	NOUN
fnp-3050	572	3	,	,	PUNCT
fnp-3050	572	4	double	double	ADJ
fnp-3050	572	5	kl	kl	PROPN
fnp-3050	572	6	,	,	PUNCT
fnp-3050	572	7	kril	kril	PROPN
fnp-3050	572	8	jj	jj	PROPN
fnp-3050	572	9	,	,	PUNCT
fnp-3050	572	10	harasty	harasty	NOUN
fnp-3050	572	11	j	j	PROPN
fnp-3050	572	12	,	,	PUNCT
fnp-3050	572	13	macdonald	macdonald	PROPN
fnp-3050	572	14	v	v	PROPN
fnp-3050	572	15	,	,	PUNCT
fnp-3050	572	16	mcritchie	mcritchie	NOUN
fnp-3050	572	17	da	da	PROPN
fnp-3050	572	18	,	,	PUNCT
fnp-3050	572	19	halliday	halliday	PROPN
fnp-3050	572	20	gm	gm	PROPN
fnp-3050	572	21	(	(	PUNCT
fnp-3050	572	22	2009	2009	NUM
fnp-3050	572	23	)	)	PUNCT
fnp-3050	572	24	white	white	ADJ
fnp-3050	572	25	matter	matter	NOUN
fnp-3050	572	26	loss	loss	NOUN
fnp-3050	572	27	in	in	ADP
fnp-3050	572	28	healthy	healthy	ADJ
fnp-3050	572	29	ageing	ageing	NOUN
fnp-3050	572	30	:	:	PUNCT
fnp-3050	572	31	a	a	DET
fnp-3050	572	32	postmortem	postmortem	NOUN
fnp-3050	572	33	analysis	analysis	NOUN
fnp-3050	572	34	.	.	PUNCT
fnp-3050	573	1	neurobiol	neurobiol	PROPN
fnp-3050	573	2	aging	age	VERB
fnp-3050	573	3	30:1288	30:1288	NUM
fnp-3050	573	4	-	-	SYM
fnp-3050	573	5	1295	1295	NUM
fnp-3050	573	6	30	30	NUM
fnp-3050	573	7	.	.	PUNCT
fnp-3050	573	8	serrano	serrano	PROPN
fnp-3050	573	9	-	-	PUNCT
fnp-3050	573	10	pozo	pozo	PROPN
fnp-3050	573	11	a	a	PROPN
fnp-3050	573	12	,	,	PUNCT
fnp-3050	573	13	frosch	frosch	PROPN
fnp-3050	573	14	mp	mp	PROPN
fnp-3050	573	15	,	,	PUNCT
fnp-3050	573	16	masliah	masliah	PROPN
fnp-3050	573	17	e	e	PROPN
fnp-3050	573	18	,	,	PUNCT
fnp-3050	573	19	hyman	hyman	PROPN
fnp-3050	573	20	bt	bt	PROPN
fnp-3050	573	21	(	(	PUNCT
fnp-3050	573	22	2011	2011	NUM
fnp-3050	573	23	)	)	PUNCT
fnp-3050	573	24	neuropathological	neuropathological	ADJ
fnp-3050	573	25	alterations	alteration	NOUN
fnp-3050	573	26	in	in	ADP
fnp-3050	573	27	alzheimer	alzheimer	PROPN
fnp-3050	573	28	disease	disease	PROPN
fnp-3050	573	29	.	.	PUNCT
fnp-3050	574	1	cold	cold	ADJ
fnp-3050	574	2	spring	spring	NOUN
fnp-3050	574	3	harb	harb	PROPN
fnp-3050	574	4	perspect	perspect	VERB
fnp-3050	574	5	med	med	ADJ
fnp-3050	574	6	1	1	NUM
fnp-3050	574	7	:	:	PUNCT
fnp-3050	574	8	a006189	a006189	PROPN
fnp-3050	574	9	31	31	NUM
fnp-3050	574	10	.	.	PUNCT
fnp-3050	575	1	deture	deture	PROPN
fnp-3050	575	2	ma	ma	PROPN
fnp-3050	575	3	,	,	PUNCT
fnp-3050	575	4	dickson	dickson	PROPN
fnp-3050	575	5	dw	dw	PROPN
fnp-3050	575	6	(	(	PUNCT
fnp-3050	575	7	2019	2019	NUM
fnp-3050	575	8	)	)	PUNCT
fnp-3050	575	9	the	the	DET
fnp-3050	575	10	neuropathological	neuropathological	ADJ
fnp-3050	575	11	diagnosis	diagnosis	NOUN
fnp-3050	575	12	of	of	ADP
fnp-3050	575	13	alzheimer	alzheimer	PROPN
fnp-3050	575	14	's	's	PART
fnp-3050	575	15	disease	disease	NOUN
fnp-3050	575	16	.	.	PUNCT
fnp-3050	576	1	mol	mol	ADP
fnp-3050	576	2	neurodegener	neurodegener	PROPN
fnp-3050	576	3	14:32	14:32	NUM
fnp-3050	576	4	32	32	NUM
fnp-3050	576	5	.	.	PUNCT
fnp-3050	577	1	tome	tome	NOUN
fnp-3050	577	2	so	so	ADV
fnp-3050	577	3	,	,	PUNCT
fnp-3050	577	4	vandenberghe	vandenberghe	ADJ
fnp-3050	577	5	r	r	NOUN
fnp-3050	577	6	,	,	PUNCT
fnp-3050	577	7	ospitalieri	ospitalieri	NOUN
fnp-3050	577	8	s	s	PROPN
fnp-3050	577	9	,	,	PUNCT
fnp-3050	577	10	van	van	PROPN
fnp-3050	577	11	schoor	schoor	PROPN
fnp-3050	577	12	e	e	PROPN
fnp-3050	577	13	,	,	PUNCT
fnp-3050	577	14	tousseyn	tousseyn	PROPN
fnp-3050	577	15	t	t	PROPN
fnp-3050	577	16	,	,	PUNCT
fnp-3050	577	17	otto	otto	PROPN
fnp-3050	577	18	m	m	PROPN
fnp-3050	577	19	,	,	PUNCT
fnp-3050	577	20	von	von	PROPN
fnp-3050	577	21	arnim	arnim	PROPN
fnp-3050	577	22	caf	caf	PROPN
fnp-3050	577	23	,	,	PUNCT
fnp-3050	577	24	thal	thal	PROPN
fnp-3050	577	25	dr	dr	PROPN
fnp-3050	577	26	(	(	PUNCT
fnp-3050	577	27	2020	2020	NUM
fnp-3050	577	28	)	)	PUNCT
fnp-3050	577	29	distinct	distinct	ADJ
fnp-3050	577	30	molecular	molecular	ADJ
fnp-3050	577	31	patterns	pattern	NOUN
fnp-3050	577	32	of	of	ADP
fnp-3050	577	33	tdp-43	tdp-43	PROPN
fnp-3050	577	34	pathology	pathology	PROPN
fnp-3050	577	35	in	in	ADP
fnp-3050	577	36	alzheimer	alzheimer	PROPN
fnp-3050	577	37	's	's	PART
fnp-3050	577	38	disease	disease	NOUN
fnp-3050	577	39	:	:	PUNCT
fnp-3050	577	40	relationship	relationship	NOUN
fnp-3050	577	41	with	with	ADP
fnp-3050	577	42	clinical	clinical	ADJ
fnp-3050	577	43	phenotypes	phenotype	NOUN
fnp-3050	577	44	.	.	PUNCT
fnp-3050	578	1	acta	acta	PROPN
fnp-3050	578	2	neuropathol	neuropathol	PROPN
fnp-3050	578	3	commun	commun	PROPN
fnp-3050	578	4	8:61	8:61	NUM
fnp-3050	578	5	33	33	NUM
fnp-3050	578	6	.	.	PUNCT
fnp-3050	579	1	o'brien	o'brien	PROPN
fnp-3050	579	2	rj	rj	PROPN
fnp-3050	579	3	,	,	PUNCT
fnp-3050	579	4	wong	wong	PROPN
fnp-3050	579	5	pc	pc	PROPN
fnp-3050	579	6	(	(	PUNCT
fnp-3050	579	7	2011	2011	NUM
fnp-3050	579	8	)	)	PUNCT
fnp-3050	579	9	amyloid	amyloid	NOUN
fnp-3050	579	10	precursor	precursor	NOUN
fnp-3050	579	11	protein	protein	NOUN
fnp-3050	579	12	processing	processing	NOUN
fnp-3050	579	13	and	and	CCONJ
fnp-3050	579	14	alzheimer	alzheimer	NOUN
fnp-3050	579	15	's	's	PART
fnp-3050	579	16	disease	disease	NOUN
fnp-3050	579	17	.	.	PUNCT
fnp-3050	580	1	annu	annu	PROPN
fnp-3050	580	2	rev	rev	VERB
fnp-3050	580	3	neurosci	neurosci	PROPN
fnp-3050	580	4	34:185	34:185	NUM
fnp-3050	580	5	-	-	SYM
fnp-3050	580	6	204	204	NUM
fnp-3050	580	7	34	34	NUM
fnp-3050	580	8	.	.	PUNCT
fnp-3050	581	1	goldgaber	goldgaber	PROPN
fnp-3050	581	2	d	d	PROPN
fnp-3050	581	3	,	,	PUNCT
fnp-3050	581	4	lerman	lerman	PROPN
fnp-3050	581	5	mi	mi	PROPN
fnp-3050	581	6	,	,	PUNCT
fnp-3050	581	7	mcbride	mcbride	PROPN
fnp-3050	581	8	ow	ow	PROPN
fnp-3050	581	9	,	,	PUNCT
fnp-3050	581	10	saffiotti	saffiotti	PROPN
fnp-3050	581	11	u	u	NOUN
fnp-3050	581	12	,	,	PUNCT
fnp-3050	581	13	gajdusek	gajdusek	VERB
fnp-3050	581	14	dc	dc	PROPN
fnp-3050	581	15	(	(	PUNCT
fnp-3050	581	16	1987	1987	NUM
fnp-3050	581	17	)	)	PUNCT
fnp-3050	581	18	characterization	characterization	NOUN
fnp-3050	581	19	and	and	CCONJ
fnp-3050	581	20	chromosomal	chromosomal	ADJ
fnp-3050	581	21	localization	localization	NOUN
fnp-3050	581	22	of	of	ADP
fnp-3050	581	23	a	a	DET
fnp-3050	581	24	cdna	cdna	PROPN
fnp-3050	581	25	encoding	encode	VERB
fnp-3050	581	26	brain	brain	NOUN
fnp-3050	581	27	amyloid	amyloid	NOUN
fnp-3050	581	28	of	of	ADP
fnp-3050	581	29	alzheimer	alzheimer	PROPN
fnp-3050	581	30	's	's	PART
fnp-3050	581	31	disease	disease	NOUN
fnp-3050	581	32	.	.	PUNCT
fnp-3050	582	1	science	science	NOUN
fnp-3050	582	2	235:877	235:877	PROPN
fnp-3050	582	3	-	-	PUNCT
fnp-3050	582	4	880	880	NUM
fnp-3050	582	5	35	35	NUM
fnp-3050	582	6	.	.	PUNCT
fnp-3050	583	1	tanzi	tanzi	PROPN
fnp-3050	583	2	re	re	PROPN
fnp-3050	583	3	,	,	PUNCT
fnp-3050	583	4	gusella	gusella	PROPN
fnp-3050	583	5	jf	jf	PROPN
fnp-3050	583	6	,	,	PUNCT
fnp-3050	583	7	watkins	watkins	PROPN
fnp-3050	583	8	pc	pc	PROPN
fnp-3050	583	9	,	,	PUNCT
fnp-3050	583	10	bruns	bruns	PROPN
fnp-3050	583	11	ga	ga	PROPN
fnp-3050	583	12	,	,	PUNCT
fnp-3050	583	13	st	st	PROPN
fnp-3050	583	14	george	george	PROPN
fnp-3050	583	15	-	-	PUNCT
fnp-3050	583	16	hyslop	hyslop	PROPN
fnp-3050	583	17	p	p	X
fnp-3050	583	18	,	,	PUNCT
fnp-3050	583	19	van	van	PROPN
fnp-3050	583	20	keuren	keuren	PROPN
fnp-3050	583	21	ml	ml	PROPN
fnp-3050	583	22	,	,	PUNCT
fnp-3050	583	23	patterson	patterson	PROPN
fnp-3050	583	24	d	d	PROPN
fnp-3050	583	25	,	,	PUNCT
fnp-3050	583	26	pagan	pagan	PROPN
fnp-3050	583	27	s	s	PART
fnp-3050	583	28	,	,	PUNCT
fnp-3050	583	29	kurnit	kurnit	PROPN
fnp-3050	583	30	dm	dm	PROPN
fnp-3050	583	31	,	,	PUNCT
fnp-3050	583	32	neve	neve	X
fnp-3050	583	33	rl	rl	PROPN
fnp-3050	583	34	(	(	PUNCT
fnp-3050	583	35	1987	1987	NUM
fnp-3050	583	36	)	)	PUNCT
fnp-3050	583	37	amyloid	amyloid	NOUN
fnp-3050	583	38	beta	beta	ADJ
fnp-3050	583	39	protein	protein	NOUN
fnp-3050	583	40	gene	gene	NOUN
fnp-3050	583	41	:	:	PUNCT
fnp-3050	583	42	cdna	cdna	PROPN
fnp-3050	583	43	,	,	PUNCT
fnp-3050	583	44	mrna	mrna	NOUN
fnp-3050	583	45	distribution	distribution	NOUN
fnp-3050	583	46	,	,	PUNCT
fnp-3050	583	47	and	and	CCONJ
fnp-3050	583	48	genetic	genetic	ADJ
fnp-3050	583	49	linkage	linkage	NOUN
fnp-3050	583	50	near	near	ADP
fnp-3050	583	51	the	the	DET
fnp-3050	583	52	alzheimer	alzheimer	PROPN
fnp-3050	583	53	locus	locus	NOUN
fnp-3050	583	54	.	.	PUNCT
fnp-3050	584	1	science	science	NOUN
fnp-3050	584	2	235:880	235:880	NUM
fnp-3050	584	3	-	-	SYM
fnp-3050	584	4	884	884	NUM
fnp-3050	584	5	36	36	NUM
fnp-3050	584	6	.	.	PUNCT
fnp-3050	585	1	coronel	coronel	PROPN
fnp-3050	585	2	r	r	PROPN
fnp-3050	585	3	,	,	PUNCT
fnp-3050	585	4	bernabeu	bernabeu	NOUN
fnp-3050	585	5	-	-	PUNCT
fnp-3050	585	6	zornoza	zornoza	PROPN
fnp-3050	585	7	a	a	PRON
fnp-3050	585	8	,	,	PUNCT
fnp-3050	585	9	palmer	palmer	PROPN
fnp-3050	585	10	c	c	PROPN
fnp-3050	585	11	,	,	PUNCT
fnp-3050	585	12	muniz	muniz	PROPN
fnp-3050	585	13	-	-	PUNCT
fnp-3050	585	14	moreno	moreno	PROPN
fnp-3050	585	15	m	m	PROPN
fnp-3050	585	16	,	,	PUNCT
fnp-3050	585	17	zambrano	zambrano	PROPN
fnp-3050	585	18	a	a	PROPN
fnp-3050	585	19	,	,	PUNCT
fnp-3050	585	20	cano	cano	PROPN
fnp-3050	585	21	e	e	PROPN
fnp-3050	585	22	,	,	PUNCT
fnp-3050	585	23	liste	liste	PROPN
fnp-3050	585	24	i	i	PROPN
fnp-3050	585	25	(	(	PUNCT
fnp-3050	585	26	2018	2018	NUM
fnp-3050	585	27	)	)	PUNCT
fnp-3050	585	28	role	role	NOUN
fnp-3050	585	29	of	of	ADP
fnp-3050	585	30	amyloid	amyloid	NOUN
fnp-3050	585	31	precursor	precursor	NOUN
fnp-3050	585	32	protein	protein	NOUN
fnp-3050	585	33	(	(	PUNCT
fnp-3050	585	34	app	app	NOUN
fnp-3050	585	35	)	)	PUNCT
fnp-3050	585	36	and	and	CCONJ
fnp-3050	585	37	its	its	PRON
fnp-3050	585	38	derivatives	derivative	NOUN
fnp-3050	585	39	in	in	ADP
fnp-3050	585	40	the	the	DET
fnp-3050	585	41	biology	biology	NOUN
fnp-3050	585	42	and	and	CCONJ
fnp-3050	585	43	cell	cell	NOUN
fnp-3050	586	1	fate	fate	NOUN
fnp-3050	586	2	specification	specification	NOUN
fnp-3050	586	3	of	of	ADP
fnp-3050	586	4	neural	neural	ADJ
fnp-3050	586	5	stem	stem	NOUN
fnp-3050	586	6	cells	cell	NOUN
fnp-3050	586	7	.	.	PUNCT
fnp-3050	587	1	mol	mol	ADP
fnp-3050	587	2	neurobiol	neurobiol	PROPN
fnp-3050	587	3	55:7107	55:7107	NOUN
fnp-3050	587	4	-	-	SYM
fnp-3050	587	5	7117	7117	NUM
fnp-3050	587	6	37	37	NUM
fnp-3050	587	7	.	.	PUNCT
fnp-3050	588	1	zheng	zheng	PROPN
fnp-3050	588	2	h	h	PROPN
fnp-3050	588	3	,	,	PUNCT
fnp-3050	588	4	koo	koo	PROPN
fnp-3050	588	5	eh	eh	INTJ
fnp-3050	588	6	(	(	PUNCT
fnp-3050	588	7	2011	2011	NUM
fnp-3050	588	8	)	)	PUNCT
fnp-3050	588	9	biology	biology	NOUN
fnp-3050	588	10	and	and	CCONJ
fnp-3050	588	11	pathophysiology	pathophysiology	NOUN
fnp-3050	588	12	of	of	ADP
fnp-3050	588	13	the	the	DET
fnp-3050	588	14	amyloid	amyloid	NOUN
fnp-3050	588	15	precursor	precursor	NOUN
fnp-3050	588	16	protein	protein	NOUN
fnp-3050	588	17	.	.	PUNCT
fnp-3050	589	1	mol	mol	ADP
fnp-3050	589	2	neurodegener	neurodegener	NOUN
fnp-3050	589	3	6:27	6:27	NUM
fnp-3050	589	4	38	38	NUM
fnp-3050	589	5	.	.	PUNCT
fnp-3050	590	1	kuhn	kuhn	PROPN
fnp-3050	590	2	ph	ph	PROPN
fnp-3050	590	3	,	,	PUNCT
fnp-3050	590	4	wang	wang	PROPN
fnp-3050	590	5	h	h	PROPN
fnp-3050	590	6	,	,	PUNCT
fnp-3050	590	7	dislich	dislich	PROPN
fnp-3050	590	8	b	b	PROPN
fnp-3050	590	9	,	,	PUNCT
fnp-3050	590	10	colombo	colombo	NOUN
fnp-3050	590	11	a	a	NOUN
fnp-3050	590	12	,	,	PUNCT
fnp-3050	590	13	zeitschel	zeitschel	PROPN
fnp-3050	590	14	u	u	NOUN
fnp-3050	590	15	,	,	PUNCT
fnp-3050	590	16	ellwart	ellwart	PROPN
fnp-3050	590	17	jw	jw	PROPN
fnp-3050	590	18	,	,	PUNCT
fnp-3050	590	19	kremmer	kremmer	ADJ
fnp-3050	590	20	e	e	NOUN
fnp-3050	590	21	,	,	PUNCT
fnp-3050	590	22	rossner	rossner	NOUN
fnp-3050	590	23	s	s	PROPN
fnp-3050	590	24	,	,	PUNCT
fnp-3050	590	25	lichtenthaler	lichtenthaler	ADJ
fnp-3050	590	26	sf	sf	PROPN
fnp-3050	590	27	(	(	PUNCT
fnp-3050	590	28	2010	2010	NUM
fnp-3050	590	29	)	)	PUNCT
fnp-3050	590	30	adam10	adam10	NOUN
fnp-3050	590	31	is	be	AUX
fnp-3050	590	32	the	the	DET
fnp-3050	590	33	physiologically	physiologically	ADV
fnp-3050	590	34	relevant	relevant	ADJ
fnp-3050	590	35	,	,	PUNCT
fnp-3050	590	36	constitutive	constitutive	ADJ
fnp-3050	590	37	alpha	alpha	NOUN
fnp-3050	590	38	-	-	PUNCT
fnp-3050	590	39	secretase	secretase	NOUN
fnp-3050	590	40	of	of	ADP
fnp-3050	590	41	the	the	DET
fnp-3050	590	42	amyloid	amyloid	NOUN
fnp-3050	590	43	precursor	precursor	NOUN
fnp-3050	590	44	protein	protein	NOUN
fnp-3050	590	45	in	in	ADP
fnp-3050	590	46	primary	primary	ADJ
fnp-3050	590	47	neurons	neuron	NOUN
fnp-3050	590	48	.	.	PUNCT
fnp-3050	591	1	embo	embo	PROPN
fnp-3050	591	2	j	j	PROPN
fnp-3050	591	3	29:3020	29:3020	PROPN
fnp-3050	591	4	-	-	SYM
fnp-3050	591	5	3032	3032	NUM
fnp-3050	591	6	39	39	NUM
fnp-3050	591	7	.	.	PUNCT
fnp-3050	592	1	postina	postina	NOUN
fnp-3050	592	2	r	r	PROPN
fnp-3050	592	3	,	,	PUNCT
fnp-3050	592	4	schroeder	schroeder	PROPN
fnp-3050	592	5	a	a	PRON
fnp-3050	592	6	,	,	PUNCT
fnp-3050	592	7	dewachter	dewachter	X
fnp-3050	592	8	i	i	PROPN
fnp-3050	592	9	,	,	PUNCT
fnp-3050	592	10	bohl	bohl	PROPN
fnp-3050	592	11	j	j	PROPN
fnp-3050	592	12	,	,	PUNCT
fnp-3050	592	13	schmitt	schmitt	PROPN
fnp-3050	592	14	u	u	NOUN
fnp-3050	592	15	,	,	PUNCT
fnp-3050	592	16	kojro	kojro	NOUN
fnp-3050	592	17	e	e	NOUN
fnp-3050	592	18	,	,	PUNCT
fnp-3050	592	19	prinzen	prinzen	PROPN
fnp-3050	592	20	c	c	PROPN
fnp-3050	592	21	,	,	PUNCT
fnp-3050	592	22	endres	endres	PROPN
fnp-3050	592	23	k	k	PROPN
fnp-3050	592	24	,	,	PUNCT
fnp-3050	592	25	hiemke	hiemke	PROPN
fnp-3050	592	26	c	c	NOUN
fnp-3050	592	27	,	,	PUNCT
fnp-3050	592	28	blessing	blessing	NOUN
fnp-3050	592	29	m	m	PRON
fnp-3050	592	30	,	,	PUNCT
fnp-3050	592	31	flamez	flamez	NOUN
fnp-3050	592	32	p	p	NOUN
fnp-3050	592	33	,	,	PUNCT
fnp-3050	592	34	dequenne	dequenne	VERB
fnp-3050	592	35	a	a	PRON
fnp-3050	592	36	,	,	PUNCT
fnp-3050	592	37	godaux	godaux	ADJ
fnp-3050	592	38	e	e	NOUN
fnp-3050	592	39	,	,	PUNCT
fnp-3050	592	40	van	van	PROPN
fnp-3050	592	41	leuven	leuven	PROPN
fnp-3050	592	42	f	f	PROPN
fnp-3050	592	43	,	,	PUNCT
fnp-3050	592	44	fahrenholz	fahrenholz	PROPN
fnp-3050	592	45	f	f	X
fnp-3050	592	46	(	(	PUNCT
fnp-3050	592	47	2004	2004	NUM
fnp-3050	592	48	)	)	PUNCT
fnp-3050	592	49	a	a	DET
fnp-3050	592	50	disintegrin	disintegrin	NOUN
fnp-3050	592	51	-	-	PUNCT
fnp-3050	592	52	metalloproteinase	metalloproteinase	NOUN
fnp-3050	592	53	prevents	prevent	VERB
fnp-3050	592	54	amyloid	amyloid	NOUN
fnp-3050	592	55	plaque	plaque	NOUN
fnp-3050	592	56	formation	formation	NOUN
fnp-3050	592	57	and	and	CCONJ
fnp-3050	592	58	hippocampal	hippocampal	ADJ
fnp-3050	592	59	defects	defect	NOUN
fnp-3050	592	60	in	in	ADP
fnp-3050	592	61	an	an	DET
fnp-3050	592	62	alzheimer	alzheimer	NOUN
fnp-3050	592	63	disease	disease	NOUN
fnp-3050	592	64	mouse	mouse	NOUN
fnp-3050	592	65	model	model	NOUN
fnp-3050	592	66	.	.	PUNCT
fnp-3050	593	1	j	j	PROPN
fnp-3050	593	2	clin	clin	PROPN
fnp-3050	593	3	invest	invest	VERB
fnp-3050	593	4	113:1456	113:1456	NUM
fnp-3050	593	5	-	-	SYM
fnp-3050	593	6	1464	1464	NUM
fnp-3050	593	7	40	40	NUM
fnp-3050	593	8	.	.	PUNCT
fnp-3050	594	1	kojro	kojro	PROPN
fnp-3050	594	2	e	e	PROPN
fnp-3050	594	3	,	,	PUNCT
fnp-3050	594	4	fahrenholz	fahrenholz	PROPN
fnp-3050	594	5	f	f	X
fnp-3050	594	6	(	(	PUNCT
fnp-3050	594	7	2005	2005	NUM
fnp-3050	594	8	)	)	PUNCT
fnp-3050	594	9	the	the	DET
fnp-3050	594	10	non	non	ADJ
fnp-3050	594	11	-	-	ADJ
fnp-3050	594	12	amyloidogenic	amyloidogenic	ADJ
fnp-3050	594	13	pathway	pathway	NOUN
fnp-3050	594	14	:	:	PUNCT
fnp-3050	594	15	structure	structure	NOUN
fnp-3050	594	16	and	and	CCONJ
fnp-3050	594	17	function	function	NOUN
fnp-3050	594	18	of	of	ADP
fnp-3050	594	19	alpha	alpha	NOUN
fnp-3050	594	20	-	-	PUNCT
fnp-3050	594	21	secretases	secretase	NOUN
fnp-3050	594	22	.	.	PUNCT
fnp-3050	595	1	subcell	subcell	PROPN
fnp-3050	595	2	biochem	biochem	PROPN
fnp-3050	595	3	38:105	38:105	NUM
fnp-3050	595	4	-	-	SYM
fnp-3050	595	5	127	127	NUM
fnp-3050	595	6	41	41	NUM
fnp-3050	595	7	.	.	PUNCT
fnp-3050	596	1	nhan	nhan	PROPN
fnp-3050	596	2	hs	hs	PROPN
fnp-3050	596	3	,	,	PUNCT
fnp-3050	596	4	chiang	chiang	PROPN
fnp-3050	596	5	k	k	PROPN
fnp-3050	596	6	,	,	PUNCT
fnp-3050	596	7	koo	koo	PROPN
fnp-3050	596	8	eh	eh	INTJ
fnp-3050	596	9	(	(	PUNCT
fnp-3050	596	10	2015	2015	NUM
fnp-3050	596	11	)	)	PUNCT
fnp-3050	596	12	the	the	DET
fnp-3050	596	13	multifaceted	multifaceted	ADJ
fnp-3050	596	14	nature	nature	NOUN
fnp-3050	596	15	of	of	ADP
fnp-3050	596	16	amyloid	amyloid	NOUN
fnp-3050	596	17	precursor	precursor	NOUN
fnp-3050	596	18	protein	protein	NOUN
fnp-3050	596	19	and	and	CCONJ
fnp-3050	596	20	its	its	PRON
fnp-3050	596	21	proteolytic	proteolytic	ADJ
fnp-3050	596	22	fragments	fragment	NOUN
fnp-3050	596	23	:	:	PUNCT
fnp-3050	596	24	friends	friend	NOUN
fnp-3050	596	25	and	and	CCONJ
fnp-3050	596	26	foes	foe	NOUN
fnp-3050	596	27	.	.	PUNCT
fnp-3050	597	1	acta	acta	PROPN
fnp-3050	597	2	neuropathol	neuropathol	PROPN
fnp-3050	597	3	129:1	129:1	PROPN
fnp-3050	597	4	-	-	SYM
fnp-3050	597	5	19	19	NUM
fnp-3050	597	6	42	42	NUM
fnp-3050	597	7	.	.	PUNCT
fnp-3050	598	1	de	de	PROPN
fnp-3050	598	2	chiara	chiara	PROPN
fnp-3050	598	3	g	g	PROPN
fnp-3050	598	4	,	,	PUNCT
fnp-3050	598	5	marcocci	marcocci	VERB
fnp-3050	598	6	me	i	PRON
fnp-3050	598	7	,	,	PUNCT
fnp-3050	598	8	civitelli	civitelli	PROPN
fnp-3050	598	9	l	l	PROPN
fnp-3050	598	10	,	,	PUNCT
fnp-3050	598	11	argnani	argnani	X
fnp-3050	598	12	r	r	NOUN
fnp-3050	598	13	,	,	PUNCT
fnp-3050	598	14	piacentini	piacentini	ADJ
fnp-3050	598	15	r	r	NOUN
fnp-3050	598	16	,	,	PUNCT
fnp-3050	598	17	ripoli	ripoli	NOUN
fnp-3050	598	18	c	c	NOUN
fnp-3050	598	19	,	,	PUNCT
fnp-3050	598	20	manservigi	manservigi	PROPN
fnp-3050	598	21	r	r	NOUN
fnp-3050	598	22	,	,	PUNCT
fnp-3050	598	23	grassi	grassi	PROPN
fnp-3050	598	24	c	c	NOUN
fnp-3050	598	25	,	,	PUNCT
fnp-3050	598	26	garaci	garaci	NOUN
fnp-3050	598	27	e	e	PROPN
fnp-3050	598	28	,	,	PUNCT
fnp-3050	598	29	palamara	palamara	X
fnp-3050	598	30	at	at	ADP
fnp-3050	598	31	(	(	PUNCT
fnp-3050	598	32	2010	2010	NUM
fnp-3050	598	33	)	)	PUNCT
fnp-3050	598	34	app	app	NOUN
fnp-3050	598	35	processing	processing	NOUN
fnp-3050	598	36	induced	induce	VERB
fnp-3050	598	37	by	by	ADP
fnp-3050	598	38	herpes	herpe	NOUN
fnp-3050	598	39	simplex	simplex	NOUN
fnp-3050	598	40	virus	virus	NOUN
fnp-3050	598	41	type	type	NOUN
fnp-3050	598	42	1	1	NUM
fnp-3050	598	43	(	(	PUNCT
fnp-3050	598	44	hsv-1	hsv-1	NOUN
fnp-3050	598	45	)	)	PUNCT
fnp-3050	598	46	yields	yield	VERB
fnp-3050	598	47	several	several	ADJ
fnp-3050	598	48	app	app	NOUN
fnp-3050	598	49	fragments	fragment	NOUN
fnp-3050	598	50	in	in	ADP
fnp-3050	598	51	human	human	ADJ
fnp-3050	598	52	and	and	CCONJ
fnp-3050	598	53	rat	rat	NOUN
fnp-3050	598	54	neuronal	neuronal	ADJ
fnp-3050	598	55	cells	cell	NOUN
fnp-3050	598	56	.	.	PUNCT
fnp-3050	599	1	plos	plos	PROPN
fnp-3050	599	2	one	one	NUM
fnp-3050	599	3	5	5	NUM
fnp-3050	599	4	:	:	PUNCT
fnp-3050	599	5	e13989	e13989	PROPN
fnp-3050	599	6	43	43	NUM
fnp-3050	599	7	.	.	PUNCT
fnp-3050	600	1	portelius	portelius	PROPN
fnp-3050	600	2	e	e	NOUN
fnp-3050	600	3	,	,	PUNCT
fnp-3050	600	4	brinkmalm	brinkmalm	VERB
fnp-3050	600	5	g	g	PROPN
fnp-3050	600	6	,	,	PUNCT
fnp-3050	600	7	tran	tran	PROPN
fnp-3050	600	8	a	a	PROPN
fnp-3050	600	9	,	,	PUNCT
fnp-3050	600	10	andreasson	andreasson	NOUN
fnp-3050	600	11	u	u	PROPN
fnp-3050	600	12	,	,	PUNCT
fnp-3050	600	13	zetterberg	zetterberg	PROPN
fnp-3050	600	14	h	h	PROPN
fnp-3050	600	15	,	,	PUNCT
fnp-3050	600	16	westman	westman	NOUN
fnp-3050	600	17	-	-	PUNCT
fnp-3050	600	18	brinkmalm	brinkmalm	NOUN
fnp-3050	600	19	a	a	PRON
fnp-3050	600	20	,	,	PUNCT
fnp-3050	600	21	blennow	blennow	ADV
fnp-3050	600	22	k	k	PROPN
fnp-3050	600	23	,	,	PUNCT
fnp-3050	600	24	ohrfelt	ohrfelt	VERB
fnp-3050	600	25	a	a	DET
fnp-3050	600	26	(	(	PUNCT
fnp-3050	600	27	2010	2010	NUM
fnp-3050	600	28	)	)	PUNCT
fnp-3050	600	29	identification	identification	NOUN
fnp-3050	600	30	of	of	ADP
fnp-3050	600	31	novel	novel	ADJ
fnp-3050	600	32	n	n	CCONJ
fnp-3050	600	33	-	-	PUNCT
fnp-3050	600	34	terminal	terminal	ADJ
fnp-3050	600	35	fragments	fragment	NOUN
fnp-3050	600	36	of	of	ADP
fnp-3050	600	37	amyloid	amyloid	NOUN
fnp-3050	600	38	precursor	precursor	NOUN
fnp-3050	600	39	protein	protein	NOUN
fnp-3050	600	40	in	in	ADP
fnp-3050	600	41	cerebrospinal	cerebrospinal	ADJ
fnp-3050	600	42	fluid	fluid	NOUN
fnp-3050	600	43	.	.	PUNCT
fnp-3050	601	1	exp	exp	NOUN
fnp-3050	601	2	neurol	neurol	PROPN
fnp-3050	601	3	223:351	223:351	PROPN
fnp-3050	601	4	-	-	PUNCT
fnp-3050	601	5	358	358	NUM
fnp-3050	601	6	44	44	NUM
fnp-3050	601	7	.	.	PUNCT
fnp-3050	602	1	frost	frost	NOUN
fnp-3050	602	2	gr	gr	PROPN
fnp-3050	602	3	,	,	PUNCT
fnp-3050	602	4	li	li	PROPN
fnp-3050	602	5	ym	ym	PROPN
fnp-3050	602	6	(	(	PUNCT
fnp-3050	602	7	2017	2017	NUM
fnp-3050	602	8	)	)	PUNCT
fnp-3050	602	9	the	the	DET
fnp-3050	602	10	role	role	NOUN
fnp-3050	602	11	of	of	ADP
fnp-3050	602	12	astrocytes	astrocyte	NOUN
fnp-3050	602	13	in	in	ADP
fnp-3050	602	14	amyloid	amyloid	NOUN
fnp-3050	602	15	production	production	NOUN
fnp-3050	602	16	and	and	CCONJ
fnp-3050	602	17	alzheimer	alzheimer	NOUN
fnp-3050	602	18	's	's	PART
fnp-3050	602	19	disease	disease	NOUN
fnp-3050	602	20	.	.	PUNCT
fnp-3050	603	1	open	open	ADJ
fnp-3050	603	2	biol	biol	PROPN
fnp-3050	603	3	7	7	NUM
fnp-3050	603	4	45	45	NUM
fnp-3050	603	5	.	.	PUNCT
fnp-3050	604	1	peters	peters	PROPN
fnp-3050	604	2	f	f	PROPN
fnp-3050	604	3	,	,	PUNCT
fnp-3050	604	4	salihoglu	salihoglu	PROPN
fnp-3050	604	5	h	h	PROPN
fnp-3050	604	6	,	,	PUNCT
fnp-3050	604	7	rodrigues	rodrigues	PROPN
fnp-3050	604	8	e	e	PROPN
fnp-3050	604	9	,	,	PUNCT
fnp-3050	604	10	herzog	herzog	PROPN
fnp-3050	604	11	e	e	PROPN
fnp-3050	604	12	,	,	PUNCT
fnp-3050	604	13	blume	blume	PROPN
fnp-3050	604	14	t	t	PROPN
fnp-3050	604	15	,	,	PUNCT
fnp-3050	604	16	filser	filser	PROPN
fnp-3050	604	17	s	s	PROPN
fnp-3050	604	18	,	,	PUNCT
fnp-3050	604	19	dorostkar	dorostkar	PROPN
fnp-3050	604	20	m	m	PROPN
fnp-3050	604	21	,	,	PUNCT
fnp-3050	604	22	shimshek	shimshek	PROPN
fnp-3050	604	23	dr	dr	PROPN
fnp-3050	604	24	,	,	PUNCT
fnp-3050	604	25	brose	brose	PROPN
fnp-3050	604	26	n	n	PROPN
fnp-3050	604	27	,	,	PUNCT
fnp-3050	604	28	neumann	neumann	PROPN
fnp-3050	604	29	u	u	PROPN
fnp-3050	604	30	,	,	PUNCT
fnp-3050	604	31	herms	herms	PROPN
fnp-3050	604	32	j	j	PROPN
fnp-3050	604	33	(	(	PUNCT
fnp-3050	604	34	2018	2018	NUM
fnp-3050	604	35	)	)	PUNCT
fnp-3050	605	1	bace1	bace1	NOUN
fnp-3050	605	2	inhibition	inhibition	VERB
fnp-3050	605	3	more	more	ADV
fnp-3050	605	4	effectively	effectively	ADV
fnp-3050	605	5	suppresses	suppress	VERB
fnp-3050	605	6	initiation	initiation	NOUN
fnp-3050	605	7	than	than	ADP
fnp-3050	605	8	progression	progression	NOUN
fnp-3050	605	9	of	of	ADP
fnp-3050	605	10	beta	beta	NOUN
fnp-3050	605	11	-	-	PUNCT
fnp-3050	605	12	amyloid	amyloid	NOUN
fnp-3050	605	13	pathology	pathology	NOUN
fnp-3050	605	14	.	.	PUNCT
fnp-3050	606	1	acta	acta	PROPN
fnp-3050	606	2	neuropathol	neuropathol	PROPN
fnp-3050	606	3	135:695	135:695	NUM
fnp-3050	606	4	-	-	SYM
fnp-3050	606	5	710	710	NUM
fnp-3050	606	6	46	46	NUM
fnp-3050	606	7	.	.	PUNCT
fnp-3050	607	1	volloch	volloch	PROPN
fnp-3050	607	2	v	v	PROPN
fnp-3050	607	3	,	,	PUNCT
fnp-3050	607	4	olsen	olsen	NOUN
fnp-3050	607	5	b	b	PROPN
fnp-3050	607	6	,	,	PUNCT
fnp-3050	607	7	rits	rits	X
fnp-3050	607	8	s	s	X
fnp-3050	607	9	(	(	PUNCT
fnp-3050	607	10	2020	2020	NUM
fnp-3050	607	11	)	)	PUNCT
fnp-3050	607	12	alzheimer	alzheimer	PROPN
fnp-3050	607	13	's	's	PART
fnp-3050	607	14	disease	disease	NOUN
fnp-3050	607	15	is	be	AUX
fnp-3050	607	16	driven	drive	VERB
fnp-3050	607	17	by	by	ADP
fnp-3050	607	18	intraneuronally	intraneuronally	ADV
fnp-3050	607	19	retained	retain	VERB
fnp-3050	607	20	beta	beta	NOUN
fnp-3050	607	21	-	-	PUNCT
fnp-3050	607	22	amyloid	amyloid	NOUN
fnp-3050	607	23	produced	produce	VERB
fnp-3050	607	24	in	in	ADP
fnp-3050	607	25	the	the	DET
fnp-3050	607	26	ad	ad	NOUN
fnp-3050	607	27	-	-	PUNCT
fnp-3050	607	28	specific	specific	ADJ
fnp-3050	607	29	,	,	PUNCT
fnp-3050	607	30	beta	beta	NOUN
fnp-3050	607	31	-	-	PUNCT
fnp-3050	607	32	app	app	ADJ
fnp-3050	607	33	-	-	PUNCT
fnp-3050	607	34	independent	independent	ADJ
fnp-3050	607	35	pathway	pathway	NOUN
fnp-3050	607	36	:	:	PUNCT
fnp-3050	607	37	current	current	ADJ
fnp-3050	607	38	perspective	perspective	NOUN
fnp-3050	607	39	and	and	CCONJ
fnp-3050	607	40	experimental	experimental	ADJ
fnp-3050	607	41	models	model	NOUN
fnp-3050	607	42	for	for	ADP
fnp-3050	607	43	tomorrow	tomorrow	NOUN
fnp-3050	607	44	.	.	PUNCT
fnp-3050	608	1	ann	ann	PROPN
fnp-3050	608	2	integr	integr	PROPN
fnp-3050	608	3	mol	mol	ADP
fnp-3050	608	4	med	med	ADJ
fnp-3050	608	5	2:90	2:90	NUM
fnp-3050	608	6	-	-	SYM
fnp-3050	608	7	114	114	NUM
fnp-3050	608	8	47	47	NUM
fnp-3050	608	9	.	.	PUNCT
fnp-3050	609	1	yu	yu	PROPN
fnp-3050	609	2	y	y	PROPN
fnp-3050	609	3	,	,	PUNCT
fnp-3050	609	4	jans	jans	PROPN
fnp-3050	609	5	dc	dc	PROPN
fnp-3050	609	6	,	,	PUNCT
fnp-3050	609	7	winblad	winblad	PROPN
fnp-3050	609	8	b	b	NUM
fnp-3050	609	9	,	,	PUNCT
fnp-3050	609	10	tjernberg	tjernberg	PROPN
fnp-3050	609	11	lo	lo	PROPN
fnp-3050	609	12	,	,	PUNCT
fnp-3050	609	13	schedin	schedin	NOUN
fnp-3050	609	14	-	-	PUNCT
fnp-3050	609	15	weiss	weiss	NOUN
fnp-3050	609	16	s	s	X
fnp-3050	609	17	(	(	PUNCT
fnp-3050	609	18	2018	2018	NUM
fnp-3050	609	19	)	)	PUNCT
fnp-3050	609	20	neuronal	neuronal	ADJ
fnp-3050	609	21	abeta42	abeta42	NOUN
fnp-3050	609	22	is	be	AUX
fnp-3050	609	23	enriched	enrich	VERB
fnp-3050	609	24	in	in	ADP
fnp-3050	609	25	small	small	ADJ
fnp-3050	609	26	vesicles	vesicle	NOUN
fnp-3050	609	27	at	at	ADP
fnp-3050	609	28	the	the	DET
fnp-3050	609	29	presynaptic	presynaptic	ADJ
fnp-3050	609	30	side	side	NOUN
fnp-3050	609	31	of	of	ADP
fnp-3050	609	32	synapses	synapsis	NOUN
fnp-3050	609	33	.	.	PUNCT
fnp-3050	610	1	life	life	NOUN
fnp-3050	610	2	sci	sci	PROPN
fnp-3050	610	3	alliance	alliance	PROPN
fnp-3050	610	4	1	1	NUM
fnp-3050	610	5	:	:	PUNCT
fnp-3050	610	6	e201800028	e201800028	PROPN
fnp-3050	610	7	48	48	NUM
fnp-3050	610	8	.	.	PUNCT
fnp-3050	611	1	greenfield	greenfield	NOUN
fnp-3050	611	2	jp	jp	PROPN
fnp-3050	611	3	,	,	PUNCT
fnp-3050	611	4	tsai	tsai	PROPN
fnp-3050	611	5	j	j	PROPN
fnp-3050	611	6	,	,	PUNCT
fnp-3050	611	7	gouras	gouras	PROPN
fnp-3050	611	8	gk	gk	PROPN
fnp-3050	611	9	,	,	PUNCT
fnp-3050	611	10	hai	hai	PROPN
fnp-3050	611	11	b	b	PROPN
fnp-3050	611	12	,	,	PUNCT
fnp-3050	611	13	thinakaran	thinakaran	NOUN
fnp-3050	611	14	g	g	NOUN
fnp-3050	611	15	,	,	PUNCT
fnp-3050	611	16	checler	checler	NOUN
fnp-3050	611	17	f	f	PROPN
fnp-3050	611	18	,	,	PUNCT
fnp-3050	611	19	sisodia	sisodia	PROPN
fnp-3050	611	20	ss	ss	PROPN
fnp-3050	611	21	,	,	PUNCT
fnp-3050	611	22	greengard	greengard	VERB
fnp-3050	611	23	p	p	X
fnp-3050	611	24	,	,	PUNCT
fnp-3050	611	25	xu	xu	PROPN
fnp-3050	611	26	h	h	PROPN
fnp-3050	611	27	(	(	PUNCT
fnp-3050	611	28	1999	1999	NUM
fnp-3050	611	29	)	)	PUNCT
fnp-3050	611	30	endoplasmic	endoplasmic	ADJ
fnp-3050	611	31	reticulum	reticulum	NOUN
fnp-3050	611	32	and	and	CCONJ
fnp-3050	611	33	trans	trans	ADJ
fnp-3050	611	34	-	-	ADJ
fnp-3050	611	35	golgi	golgi	ADJ
fnp-3050	611	36	network	network	NOUN
fnp-3050	611	37	generate	generate	VERB
fnp-3050	611	38	distinct	distinct	ADJ
fnp-3050	611	39	populations	population	NOUN
fnp-3050	611	40	of	of	ADP
fnp-3050	611	41	alzheimer	alzheimer	PROPN
fnp-3050	611	42	beta	beta	NOUN
fnp-3050	611	43	-	-	PUNCT
fnp-3050	611	44	amyloid	amyloid	NOUN
fnp-3050	611	45	peptides	peptide	NOUN
fnp-3050	611	46	.	.	PUNCT
fnp-3050	612	1	proc	proc	PROPN
fnp-3050	612	2	natl	natl	PROPN
fnp-3050	612	3	acad	acad	PROPN
fnp-3050	612	4	sci	sci	PROPN
fnp-3050	612	5	u	u	PROPN
fnp-3050	612	6	s	s	PROPN
fnp-3050	612	7	a	a	DET
fnp-3050	612	8	96:742	96:742	NUM
fnp-3050	612	9	-	-	SYM
fnp-3050	612	10	747	747	NUM
fnp-3050	612	11	49	49	NUM
fnp-3050	612	12	.	.	PUNCT
fnp-3050	613	1	hartmann	hartmann	PROPN
fnp-3050	613	2	t	t	PROPN
fnp-3050	613	3	,	,	PUNCT
fnp-3050	613	4	bieger	bieger	PROPN
fnp-3050	613	5	sc	sc	PROPN
fnp-3050	613	6	,	,	PUNCT
fnp-3050	613	7	brühl	brühl	NOUN
fnp-3050	613	8	b	b	NOUN
fnp-3050	613	9	,	,	PUNCT
fnp-3050	613	10	tienari	tienari	PROPN
fnp-3050	613	11	pj	pj	PROPN
fnp-3050	613	12	,	,	PUNCT
fnp-3050	613	13	ida	ida	PROPN
fnp-3050	613	14	n	n	CCONJ
fnp-3050	613	15	,	,	PUNCT
fnp-3050	613	16	allsop	allsop	PROPN
fnp-3050	613	17	d	d	PROPN
fnp-3050	613	18	,	,	PUNCT
fnp-3050	613	19	roberts	roberts	PROPN
fnp-3050	613	20	gw	gw	PROPN
fnp-3050	613	21	,	,	PUNCT
fnp-3050	613	22	masters	master	NOUN
fnp-3050	613	23	cl	cl	NOUN
fnp-3050	613	24	,	,	PUNCT
fnp-3050	613	25	dotti	dotti	PROPN
fnp-3050	613	26	cg	cg	PROPN
fnp-3050	613	27	,	,	PUNCT
fnp-3050	613	28	unsicker	unsicker	PROPN
fnp-3050	613	29	k	k	PROPN
fnp-3050	613	30	,	,	PUNCT
fnp-3050	613	31	beyreuther	beyreuther	PROPN
fnp-3050	613	32	k	k	PROPN
fnp-3050	613	33	(	(	PUNCT
fnp-3050	613	34	1997	1997	NUM
fnp-3050	613	35	)	)	PUNCT
fnp-3050	613	36	distinct	distinct	ADJ
fnp-3050	613	37	sites	site	NOUN
fnp-3050	613	38	of	of	ADP
fnp-3050	613	39	intracellular	intracellular	ADJ
fnp-3050	613	40	production	production	NOUN
fnp-3050	613	41	for	for	ADP
fnp-3050	613	42	alzheimer	alzheimer	PROPN
fnp-3050	613	43	's	's	PART
fnp-3050	613	44	disease	disease	NOUN
fnp-3050	613	45	a	a	DET
fnp-3050	613	46	beta40/42	beta40/42	NOUN
fnp-3050	613	47	amyloid	amyloid	NOUN
fnp-3050	613	48	peptides	peptide	NOUN
fnp-3050	613	49	.	.	PUNCT
fnp-3050	614	1	nat	nat	PROPN
fnp-3050	614	2	med	me	VERB
fnp-3050	614	3	3:1016	3:1016	NUM
fnp-3050	614	4	-	-	SYM
fnp-3050	614	5	1020	1020	NUM
fnp-3050	614	6	50	50	NUM
fnp-3050	614	7	.	.	PUNCT
fnp-3050	615	1	hellström	hellström	NOUN
fnp-3050	615	2	-	-	PUNCT
fnp-3050	615	3	lindahl	lindahl	PROPN
fnp-3050	615	4	e	e	PROPN
fnp-3050	615	5	,	,	PUNCT
fnp-3050	615	6	viitanen	viitanen	PROPN
fnp-3050	615	7	m	m	PROPN
fnp-3050	615	8	,	,	PUNCT
fnp-3050	615	9	marutle	marutle	VERB
fnp-3050	615	10	a	a	DET
fnp-3050	615	11	(	(	PUNCT
fnp-3050	615	12	2009	2009	NUM
fnp-3050	615	13	)	)	PUNCT
fnp-3050	615	14	comparison	comparison	NOUN
fnp-3050	615	15	of	of	ADP
fnp-3050	615	16	abeta	abeta	PROPN
fnp-3050	615	17	levels	level	NOUN
fnp-3050	615	18	in	in	ADP
fnp-3050	615	19	the	the	DET
fnp-3050	615	20	brain	brain	NOUN
fnp-3050	615	21	of	of	ADP
fnp-3050	615	22	familial	familial	ADJ
fnp-3050	615	23	and	and	CCONJ
fnp-3050	615	24	sporadic	sporadic	ADJ
fnp-3050	615	25	alzheimer	alzheimer	PROPN
fnp-3050	615	26	's	's	PART
fnp-3050	615	27	disease	disease	NOUN
fnp-3050	615	28	.	.	PUNCT
fnp-3050	616	1	neurochem	neurochem	PROPN
fnp-3050	616	2	int	int	VERB
fnp-3050	616	3	55:243	55:243	NUM
fnp-3050	616	4	-	-	SYM
fnp-3050	616	5	252	252	NUM
fnp-3050	616	6	51	51	NUM
fnp-3050	616	7	.	.	PUNCT
fnp-3050	617	1	walsh	walsh	PROPN
fnp-3050	617	2	dm	dm	PROPN
fnp-3050	617	3	,	,	PUNCT
fnp-3050	617	4	selkoe	selkoe	ADJ
fnp-3050	617	5	dj	dj	X
fnp-3050	617	6	(	(	PUNCT
fnp-3050	617	7	2007	2007	NUM
fnp-3050	617	8	)	)	PUNCT
fnp-3050	617	9	a	a	DET
fnp-3050	617	10	beta	beta	NOUN
fnp-3050	617	11	oligomers	oligomer	NOUN
fnp-3050	617	12	a	a	DET
fnp-3050	617	13	decade	decade	NOUN
fnp-3050	617	14	of	of	ADP
fnp-3050	617	15	discovery	discovery	NOUN
fnp-3050	617	16	.	.	PUNCT
fnp-3050	618	1	j	j	PROPN
fnp-3050	618	2	neurochem	neurochem	PROPN
fnp-3050	618	3	101:1172	101:1172	PROPN
fnp-3050	618	4	-	-	SYM
fnp-3050	618	5	1184	1184	NUM
fnp-3050	618	6	52	52	NUM
fnp-3050	618	7	.	.	PUNCT
fnp-3050	619	1	galvao	galvao	PROPN
fnp-3050	619	2	f	f	PROPN
fnp-3050	619	3	,	,	PUNCT
fnp-3050	619	4	jr	jr	PROPN
fnp-3050	619	5	.	.	PROPN
fnp-3050	619	6	,	,	PUNCT
fnp-3050	619	7	grokoski	grokoski	PROPN
fnp-3050	619	8	kc	kc	PROPN
fnp-3050	619	9	,	,	PUNCT
fnp-3050	619	10	da	da	PROPN
fnp-3050	619	11	silva	silva	PROPN
fnp-3050	619	12	bb	bb	PROPN
fnp-3050	619	13	,	,	PUNCT
fnp-3050	619	14	lamers	lamer	NOUN
fnp-3050	619	15	ml	ml	PROPN
fnp-3050	619	16	,	,	PUNCT
fnp-3050	619	17	siqueira	siqueira	PROPN
fnp-3050	619	18	ir	ir	PROPN
fnp-3050	619	19	(	(	PUNCT
fnp-3050	619	20	2019	2019	NUM
fnp-3050	619	21	)	)	PUNCT
fnp-3050	619	22	the	the	DET
fnp-3050	619	23	amyloid	amyloid	NOUN
fnp-3050	619	24	precursor	precursor	NOUN
fnp-3050	619	25	protein	protein	NOUN
fnp-3050	619	26	(	(	PUNCT
fnp-3050	619	27	app	app	NOUN
fnp-3050	619	28	)	)	PUNCT
fnp-3050	619	29	processing	processing	NOUN
fnp-3050	619	30	as	as	ADP
fnp-3050	619	31	a	a	DET
fnp-3050	619	32	biological	biological	ADJ
fnp-3050	619	33	link	link	NOUN
fnp-3050	619	34	between	between	ADP
fnp-3050	619	35	alzheimer	alzheimer	PROPN
fnp-3050	619	36	's	's	PART
fnp-3050	619	37	disease	disease	NOUN
fnp-3050	619	38	and	and	CCONJ
fnp-3050	619	39	cancer	cancer	NOUN
fnp-3050	619	40	.	.	PUNCT
fnp-3050	620	1	ageing	age	VERB
fnp-3050	620	2	res	re	NOUN
fnp-3050	620	3	rev	rev	VERB
fnp-3050	620	4	49:83	49:83	NUM
fnp-3050	620	5	-	-	SYM
fnp-3050	620	6	91	91	NUM
fnp-3050	620	7	53	53	NUM
fnp-3050	620	8	.	.	PUNCT
fnp-3050	621	1	pinnix	pinnix	PROPN
fnp-3050	621	2	i	i	PRON
fnp-3050	621	3	,	,	PUNCT
fnp-3050	621	4	ghiso	ghiso	PROPN
fnp-3050	621	5	ja	ja	PROPN
fnp-3050	621	6	,	,	PUNCT
fnp-3050	621	7	pappolla	pappolla	PROPN
fnp-3050	621	8	ma	ma	PROPN
fnp-3050	621	9	,	,	PUNCT
fnp-3050	621	10	sambamurti	sambamurti	PROPN
fnp-3050	621	11	k	k	PROPN
fnp-3050	621	12	(	(	PUNCT
fnp-3050	621	13	2013	2013	NUM
fnp-3050	621	14	)	)	PUNCT
fnp-3050	621	15	major	major	ADJ
fnp-3050	621	16	carboxyl	carboxyl	NOUN
fnp-3050	621	17	terminal	terminal	NOUN
fnp-3050	621	18	fragments	fragment	NOUN
fnp-3050	621	19	generated	generate	VERB
fnp-3050	621	20	by	by	ADP
fnp-3050	621	21	gamma	gamma	NOUN
fnp-3050	621	22	-	-	PUNCT
fnp-3050	621	23	secretase	secretase	NOUN
fnp-3050	621	24	processing	processing	NOUN
fnp-3050	621	25	of	of	ADP
fnp-3050	621	26	the	the	DET
fnp-3050	621	27	alzheimer	alzheimer	PROPN
fnp-3050	621	28	amyloid	amyloid	PROPN
fnp-3050	621	29	precursor	precursor	NOUN
fnp-3050	621	30	are	be	AUX
fnp-3050	621	31	50	50	NUM
fnp-3050	621	32	and	and	CCONJ
fnp-3050	621	33	51	51	NUM
fnp-3050	621	34	amino	amino	NOUN
fnp-3050	621	35	acids	acid	NOUN
fnp-3050	621	36	long	long	ADV
fnp-3050	621	37	.	.	PUNCT
fnp-3050	622	1	am	be	AUX
fnp-3050	622	2	j	j	PROPN
fnp-3050	622	3	geriatr	geriatr	ADJ
fnp-3050	622	4	psychiatry	psychiatry	NOUN
fnp-3050	622	5	21:474	21:474	PROPN
fnp-3050	622	6	-	-	SYM
fnp-3050	622	7	483	483	NUM
fnp-3050	622	8	54	54	NUM
fnp-3050	622	9	.	.	PUNCT
fnp-3050	623	1	kametani	kametani	PROPN
fnp-3050	623	2	f	f	PROPN
fnp-3050	623	3	(	(	PUNCT
fnp-3050	623	4	2008	2008	NUM
fnp-3050	623	5	)	)	PUNCT
fnp-3050	623	6	epsilon	epsilon	PROPN
fnp-3050	623	7	-	-	PUNCT
fnp-3050	623	8	secretase	secretase	NOUN
fnp-3050	623	9	:	:	PUNCT
fnp-3050	623	10	reduction	reduction	NOUN
fnp-3050	623	11	of	of	ADP
fnp-3050	623	12	amyloid	amyloid	NOUN
fnp-3050	623	13	precursor	precursor	NOUN
fnp-3050	623	14	protein	protein	NOUN
fnp-3050	623	15	epsilon	epsilon	NOUN
fnp-3050	623	16	-	-	PUNCT
fnp-3050	623	17	site	site	NOUN
fnp-3050	623	18	cleavage	cleavage	NOUN
fnp-3050	623	19	in	in	ADP
fnp-3050	623	20	alzheimer	alzheimer	PROPN
fnp-3050	623	21	's	's	PART
fnp-3050	623	22	disease	disease	NOUN
fnp-3050	623	23	.	.	PUNCT
fnp-3050	624	1	curr	curr	PROPN
fnp-3050	624	2	alzheimer	alzheimer	PROPN
fnp-3050	624	3	res	res	PROPN
fnp-3050	624	4	5:165	5:165	NUM
fnp-3050	624	5	-	-	SYM
fnp-3050	624	6	171	171	NUM
fnp-3050	624	7	55	55	NUM
fnp-3050	624	8	.	.	PUNCT
fnp-3050	625	1	viswanathan	viswanathan	PROPN
fnp-3050	625	2	j	j	PROPN
fnp-3050	625	3	,	,	PUNCT
fnp-3050	625	4	haapasalo	haapasalo	PROPN
fnp-3050	625	5	a	a	X
fnp-3050	625	6	,	,	PUNCT
fnp-3050	625	7	kurkinen	kurkinen	PROPN
fnp-3050	625	8	km	km	PROPN
fnp-3050	625	9	,	,	PUNCT
fnp-3050	625	10	natunen	natunen	PROPN
fnp-3050	625	11	t	t	PROPN
fnp-3050	625	12	,	,	PUNCT
fnp-3050	625	13	mäkinen	mäkinen	NOUN
fnp-3050	625	14	p	p	NOUN
fnp-3050	625	15	,	,	PUNCT
fnp-3050	625	16	bertram	bertram	PROPN
fnp-3050	625	17	l	l	PROPN
fnp-3050	625	18	,	,	PUNCT
fnp-3050	625	19	soininen	soininen	NOUN
fnp-3050	625	20	h	h	NOUN
fnp-3050	625	21	,	,	PUNCT
fnp-3050	625	22	tanzi	tanzi	PROPN
fnp-3050	625	23	re	re	PROPN
fnp-3050	625	24	,	,	PUNCT
fnp-3050	625	25	hiltunen	hiltunen	PROPN
fnp-3050	625	26	m	m	PROPN
fnp-3050	625	27	(	(	PUNCT
fnp-3050	625	28	2013	2013	NUM
fnp-3050	625	29	)	)	PUNCT
fnp-3050	625	30	ubiquilin-1	ubiquilin-1	NUM
fnp-3050	625	31	modulates	modulate	VERB
fnp-3050	625	32	gamma	gamma	NOUN
fnp-3050	625	33	-	-	PUNCT
fnp-3050	625	34	secretase	secretase	NOUN
fnp-3050	625	35	-	-	PUNCT
fnp-3050	625	36	mediated	mediate	VERB
fnp-3050	625	37	epsilon	epsilon	NOUN
fnp-3050	625	38	-	-	PUNCT
fnp-3050	625	39	site	site	NOUN
fnp-3050	625	40	cleavage	cleavage	NOUN
fnp-3050	625	41	in	in	ADP
fnp-3050	625	42	neuronal	neuronal	ADJ
fnp-3050	625	43	cells	cell	NOUN
fnp-3050	625	44	.	.	PUNCT
fnp-3050	626	1	biochemistry	biochemistry	NOUN
fnp-3050	626	2	52:3899	52:3899	PROPN
fnp-3050	626	3	-	-	SYM
fnp-3050	626	4	3912	3912	NUM
fnp-3050	626	5	56	56	NUM
fnp-3050	626	6	.	.	PUNCT
fnp-3050	627	1	krstic	krstic	PROPN
fnp-3050	627	2	d	d	PROPN
fnp-3050	627	3	,	,	PUNCT
fnp-3050	627	4	knuesel	knuesel	PROPN
fnp-3050	627	5	i	i	PROPN
fnp-3050	627	6	(	(	PUNCT
fnp-3050	627	7	2013	2013	NUM
fnp-3050	627	8	)	)	PUNCT
fnp-3050	627	9	deciphering	decipher	VERB
fnp-3050	627	10	the	the	DET
fnp-3050	627	11	mechanism	mechanism	NOUN
fnp-3050	627	12	underlying	underlie	VERB
fnp-3050	627	13	late	late	ADJ
fnp-3050	627	14	-	-	PUNCT
fnp-3050	627	15	onset	onset	NOUN
fnp-3050	627	16	alzheimer	alzheimer	NOUN
fnp-3050	627	17	disease	disease	NOUN
fnp-3050	627	18	.	.	PUNCT
fnp-3050	628	1	nat	nat	PROPN
fnp-3050	628	2	rev	rev	VERB
fnp-3050	628	3	neurol	neurol	PROPN
fnp-3050	628	4	9:25	9:25	PROPN
fnp-3050	628	5	-	-	SYM
fnp-3050	628	6	34	34	NUM
fnp-3050	628	7	57	57	NUM
fnp-3050	628	8	.	.	PUNCT
fnp-3050	629	1	michno	michno	PROPN
fnp-3050	629	2	w	w	PROPN
fnp-3050	629	3	,	,	PUNCT
fnp-3050	629	4	wehrli	wehrli	NOUN
fnp-3050	629	5	p	p	NOUN
fnp-3050	629	6	,	,	PUNCT
fnp-3050	629	7	meier	meier	PROPN
fnp-3050	629	8	sr	sr	PROPN
fnp-3050	629	9	,	,	PUNCT
fnp-3050	629	10	sehlin	sehlin	PROPN
fnp-3050	629	11	d	d	PROPN
fnp-3050	629	12	,	,	PUNCT
fnp-3050	629	13	syvänen	syvänen	VERB
fnp-3050	629	14	s	s	PROPN
fnp-3050	629	15	,	,	PUNCT
fnp-3050	629	16	zetterberg	zetterberg	PROPN
fnp-3050	629	17	h	h	PROPN
fnp-3050	629	18	,	,	PUNCT
fnp-3050	629	19	blennow	blennow	ADV
fnp-3050	629	20	k	k	PROPN
fnp-3050	629	21	,	,	PUNCT
fnp-3050	629	22	hanrieder	hanrieder	NOUN
fnp-3050	629	23	j	j	PROPN
fnp-3050	629	24	(	(	PUNCT
fnp-3050	629	25	2020	2020	NUM
fnp-3050	629	26	)	)	PUNCT
fnp-3050	629	27	chemical	chemical	NOUN
fnp-3050	629	28	imaging	imaging	NOUN
fnp-3050	629	29	of	of	ADP
fnp-3050	629	30	evolving	evolve	VERB
fnp-3050	629	31	amyloid	amyloid	NOUN
fnp-3050	629	32	plaque	plaque	NOUN
fnp-3050	629	33	pathology	pathology	NOUN
fnp-3050	629	34	and	and	CCONJ
fnp-3050	629	35	associated	associate	VERB
fnp-3050	629	36	abeta	abeta	PROPN
fnp-3050	629	37	peptide	peptide	NOUN
fnp-3050	629	38	aggregation	aggregation	NOUN
fnp-3050	629	39	in	in	ADP
fnp-3050	629	40	a	a	DET
fnp-3050	629	41	transgenic	transgenic	NOUN
fnp-3050	629	42	mouse	mouse	NOUN
fnp-3050	629	43	model	model	NOUN
fnp-3050	629	44	of	of	ADP
fnp-3050	629	45	alzheimer	alzheimer	PROPN
fnp-3050	629	46	's	's	PART
fnp-3050	629	47	disease	disease	NOUN
fnp-3050	629	48	.	.	PUNCT
fnp-3050	630	1	j	j	PROPN
fnp-3050	630	2	neurochem	neurochem	ADV
fnp-3050	630	3	152:602	152:602	PROPN
fnp-3050	630	4	-	-	SYM
fnp-3050	630	5	616	616	NUM
fnp-3050	630	6	58	58	NUM
fnp-3050	630	7	.	.	PUNCT
fnp-3050	631	1	masters	master	NOUN
fnp-3050	631	2	cl	cl	PROPN
fnp-3050	631	3	,	,	PUNCT
fnp-3050	631	4	bateman	bateman	NOUN
fnp-3050	631	5	r	r	PROPN
fnp-3050	631	6	,	,	PUNCT
fnp-3050	631	7	blennow	blennow	ADV
fnp-3050	631	8	k	k	PROPN
fnp-3050	631	9	,	,	PUNCT
fnp-3050	631	10	rowe	rowe	PROPN
fnp-3050	631	11	cc	cc	PROPN
fnp-3050	631	12	,	,	PUNCT
fnp-3050	631	13	sperling	sperling	PROPN
fnp-3050	631	14	ra	ra	PROPN
fnp-3050	631	15	,	,	PUNCT
fnp-3050	631	16	cummings	cummings	PROPN
fnp-3050	631	17	jl	jl	PROPN
fnp-3050	631	18	(	(	PUNCT
fnp-3050	631	19	2015	2015	NUM
fnp-3050	631	20	)	)	PUNCT
fnp-3050	631	21	alzheimer	alzheimer	PROPN
fnp-3050	631	22	's	's	PART
fnp-3050	631	23	disease	disease	NOUN
fnp-3050	631	24	.	.	PUNCT
fnp-3050	632	1	nat	nat	PROPN
fnp-3050	632	2	rev	rev	VERB
fnp-3050	632	3	dis	dis	PROPN
fnp-3050	632	4	primers	primer	NOUN
fnp-3050	632	5	1:15056	1:15056	NUM
fnp-3050	632	6	59	59	NUM
fnp-3050	632	7	.	.	PUNCT
fnp-3050	633	1	sil	sil	PROPN
fnp-3050	633	2	s	s	PROPN
fnp-3050	633	3	,	,	PUNCT
fnp-3050	633	4	hu	hu	PROPN
fnp-3050	633	5	g	g	PROPN
fnp-3050	633	6	,	,	PUNCT
fnp-3050	633	7	liao	liao	PROPN
fnp-3050	633	8	k	k	PROPN
fnp-3050	633	9	,	,	PUNCT
fnp-3050	633	10	niu	niu	PROPN
fnp-3050	633	11	f	f	PROPN
fnp-3050	633	12	,	,	PUNCT
fnp-3050	633	13	callen	callen	PROPN
fnp-3050	633	14	s	s	PROPN
fnp-3050	633	15	,	,	PUNCT
fnp-3050	633	16	periyasamy	periyasamy	NOUN
fnp-3050	633	17	p	p	NOUN
fnp-3050	633	18	,	,	PUNCT
fnp-3050	633	19	fox	fox	PROPN
fnp-3050	633	20	hs	hs	PROPN
fnp-3050	633	21	,	,	PUNCT
fnp-3050	633	22	buch	buch	PROPN
fnp-3050	633	23	s	s	PART
fnp-3050	633	24	(	(	PUNCT
fnp-3050	633	25	2020	2020	NUM
fnp-3050	633	26	)	)	PUNCT
fnp-3050	633	27	hiv-1	hiv-1	PUNCT
fnp-3050	633	28	tat	tat	NOUN
fnp-3050	633	29	-	-	PUNCT
fnp-3050	633	30	mediated	mediate	VERB
fnp-3050	633	31	astrocytic	astrocytic	ADJ
fnp-3050	633	32	amyloidosis	amyloidosis	NOUN
fnp-3050	633	33	involves	involve	VERB
fnp-3050	633	34	the	the	DET
fnp-3050	633	35	hif-1alpha	hif-1alpha	NOUN
fnp-3050	633	36	/	/	SYM
fnp-3050	633	37	lncrna	lncrna	NOUN
fnp-3050	633	38	bace1	bace1	NOUN
fnp-3050	633	39	-	-	PUNCT
fnp-3050	633	40	as	as	ADV
fnp-3050	633	41	axis	axis	NOUN
fnp-3050	633	42	.	.	PUNCT
fnp-3050	634	1	plos	plos	PROPN
fnp-3050	634	2	biol	biol	PROPN
fnp-3050	634	3	18	18	NUM
fnp-3050	634	4	:	:	PUNCT
fnp-3050	634	5	e3000660	e3000660	NOUN
fnp-3050	634	6	60	60	NUM
fnp-3050	634	7	.	.	PUNCT
fnp-3050	635	1	qiang	qiang	PROPN
fnp-3050	635	2	w	w	PROPN
fnp-3050	635	3	,	,	PUNCT
fnp-3050	635	4	yau	yau	PROPN
fnp-3050	635	5	wm	wm	PROPN
fnp-3050	635	6	,	,	PUNCT
fnp-3050	635	7	lu	lu	PROPN
fnp-3050	635	8	jx	jx	PROPN
fnp-3050	635	9	,	,	PUNCT
fnp-3050	635	10	collinge	collinge	NOUN
fnp-3050	635	11	j	j	PROPN
fnp-3050	635	12	,	,	PUNCT
fnp-3050	635	13	tycko	tycko	ADJ
fnp-3050	635	14	r	r	NOUN
fnp-3050	635	15	(	(	PUNCT
fnp-3050	635	16	2017	2017	NUM
fnp-3050	635	17	)	)	PUNCT
fnp-3050	635	18	structural	structural	ADJ
fnp-3050	635	19	variation	variation	NOUN
fnp-3050	635	20	in	in	ADP
fnp-3050	635	21	amyloid	amyloid	NOUN
fnp-3050	635	22	-	-	PUNCT
fnp-3050	635	23	beta	beta	NOUN
fnp-3050	635	24	fibrils	fibril	NOUN
fnp-3050	635	25	from	from	ADP
fnp-3050	635	26	alzheimer	alzheimer	PROPN
fnp-3050	635	27	's	's	PART
fnp-3050	635	28	disease	disease	NOUN
fnp-3050	635	29	clinical	clinical	ADJ
fnp-3050	635	30	subtypes	subtype	NOUN
fnp-3050	635	31	.	.	PUNCT
fnp-3050	636	1	nature	nature	NOUN
fnp-3050	636	2	541:217	541:217	NUM
fnp-3050	636	3	-	-	SYM
fnp-3050	636	4	221	221	NUM
fnp-3050	636	5	61	61	NUM
fnp-3050	636	6	.	.	PUNCT
fnp-3050	637	1	duyckaerts	duyckaert	NOUN
fnp-3050	637	2	c	c	PROPN
fnp-3050	637	3	,	,	PUNCT
fnp-3050	637	4	delatour	delatour	NOUN
fnp-3050	637	5	b	b	NOUN
fnp-3050	637	6	,	,	PUNCT
fnp-3050	637	7	potier	potier	NOUN
fnp-3050	637	8	mc	mc	PROPN
fnp-3050	637	9	(	(	PUNCT
fnp-3050	637	10	2009	2009	NUM
fnp-3050	637	11	)	)	PUNCT
fnp-3050	637	12	classification	classification	NOUN
fnp-3050	637	13	and	and	CCONJ
fnp-3050	637	14	basic	basic	ADJ
fnp-3050	637	15	pathology	pathology	NOUN
fnp-3050	637	16	of	of	ADP
fnp-3050	637	17	alzheimer	alzheimer	PROPN
fnp-3050	637	18	disease	disease	PROPN
fnp-3050	637	19	.	.	PUNCT
fnp-3050	638	1	acta	acta	PROPN
fnp-3050	638	2	neuropathol	neuropathol	PROPN
fnp-3050	638	3	118:5	118:5	NUM
fnp-3050	638	4	-	-	SYM
fnp-3050	638	5	36	36	NUM
fnp-3050	638	6	62	62	NUM
fnp-3050	638	7	.	.	PUNCT
fnp-3050	639	1	serrano	serrano	PROPN
fnp-3050	639	2	-	-	PUNCT
fnp-3050	639	3	pozo	pozo	PROPN
fnp-3050	639	4	a	a	X
fnp-3050	639	5	,	,	PUNCT
fnp-3050	639	6	mielke	mielke	ADJ
fnp-3050	639	7	ml	ml	NOUN
fnp-3050	639	8	,	,	PUNCT
fnp-3050	639	9	gomez	gomez	PROPN
fnp-3050	639	10	-	-	PUNCT
fnp-3050	639	11	isla	isla	PROPN
fnp-3050	639	12	t	t	PROPN
fnp-3050	639	13	,	,	PUNCT
fnp-3050	639	14	betensky	betensky	PROPN
fnp-3050	639	15	ra	ra	PROPN
fnp-3050	639	16	,	,	PUNCT
fnp-3050	639	17	growdon	growdon	VERB
fnp-3050	639	18	jh	jh	PROPN
fnp-3050	639	19	,	,	PUNCT
fnp-3050	639	20	frosch	frosch	PROPN
fnp-3050	639	21	mp	mp	PROPN
fnp-3050	639	22	,	,	PUNCT
fnp-3050	639	23	hyman	hyman	PROPN
fnp-3050	639	24	bt	bt	PROPN
fnp-3050	639	25	(	(	PUNCT
fnp-3050	639	26	2011	2011	NUM
fnp-3050	639	27	)	)	PUNCT
fnp-3050	639	28	reactive	reactive	ADJ
fnp-3050	639	29	glia	glia	NOUN
fnp-3050	639	30	not	not	PART
fnp-3050	639	31	only	only	ADV
fnp-3050	639	32	associates	associate	NOUN
fnp-3050	639	33	with	with	ADP
fnp-3050	639	34	plaques	plaque	NOUN
fnp-3050	639	35	but	but	CCONJ
fnp-3050	639	36	also	also	ADV
fnp-3050	639	37	parallels	parallel	VERB
fnp-3050	639	38	tangles	tangle	NOUN
fnp-3050	639	39	in	in	ADP
fnp-3050	639	40	alzheimer	alzheimer	PROPN
fnp-3050	639	41	's	's	PART
fnp-3050	639	42	disease	disease	NOUN
fnp-3050	639	43	.	.	PUNCT
fnp-3050	640	1	am	be	AUX
fnp-3050	640	2	j	j	NOUN
fnp-3050	640	3	pathol	pathol	NOUN
fnp-3050	640	4	179:1373	179:1373	NUM
fnp-3050	640	5	-	-	SYM
fnp-3050	640	6	1384	1384	NUM
fnp-3050	640	7	63	63	NUM
fnp-3050	640	8	.	.	PUNCT
fnp-3050	641	1	thal	thal	PROPN
fnp-3050	641	2	dr	dr	PROPN
fnp-3050	641	3	,	,	PUNCT
fnp-3050	641	4	capetillo	capetillo	PROPN
fnp-3050	641	5	-	-	PUNCT
fnp-3050	641	6	zarate	zarate	NOUN
fnp-3050	641	7	e	e	NOUN
fnp-3050	641	8	,	,	PUNCT
fnp-3050	641	9	del	del	PROPN
fnp-3050	641	10	tredici	tredici	PROPN
fnp-3050	641	11	k	k	PROPN
fnp-3050	641	12	,	,	PUNCT
fnp-3050	641	13	braak	braak	PROPN
fnp-3050	641	14	h	h	PROPN
fnp-3050	641	15	(	(	PUNCT
fnp-3050	641	16	2006	2006	NUM
fnp-3050	641	17	)	)	PUNCT
fnp-3050	641	18	the	the	DET
fnp-3050	641	19	development	development	NOUN
fnp-3050	641	20	of	of	ADP
fnp-3050	641	21	amyloid	amyloid	NOUN
fnp-3050	641	22	beta	beta	NOUN
fnp-3050	641	23	protein	protein	NOUN
fnp-3050	641	24	deposits	deposit	NOUN
fnp-3050	641	25	in	in	ADP
fnp-3050	641	26	the	the	DET
fnp-3050	641	27	aged	aged	ADJ
fnp-3050	641	28	brain	brain	NOUN
fnp-3050	641	29	.	.	PUNCT
fnp-3050	642	1	sci	sci	PROPN
fnp-3050	642	2	aging	age	VERB
fnp-3050	642	3	knowledge	knowledge	NOUN
fnp-3050	642	4	environ	environ	X
fnp-3050	642	5	2006	2006	NUM
fnp-3050	642	6	:	:	PUNCT
fnp-3050	642	7	re1	re1	PROPN
fnp-3050	642	8	64	64	NUM
fnp-3050	642	9	.	.	PUNCT
fnp-3050	643	1	moro	moro	PROPN
fnp-3050	643	2	ml	ml	PROPN
fnp-3050	643	3	,	,	PUNCT
fnp-3050	643	4	phillips	phillip	NOUN
fnp-3050	643	5	as	as	ADP
fnp-3050	643	6	,	,	PUNCT
fnp-3050	643	7	gaimster	gaimster	PROPN
fnp-3050	643	8	k	k	PROPN
fnp-3050	643	9	,	,	PUNCT
fnp-3050	643	10	paul	paul	PROPN
fnp-3050	643	11	c	c	PROPN
fnp-3050	643	12	,	,	PUNCT
fnp-3050	643	13	mudher	mudher	PROPN
fnp-3050	643	14	a	a	PRON
fnp-3050	643	15	,	,	PUNCT
fnp-3050	643	16	nicoll	nicoll	PROPN
fnp-3050	643	17	jar	jar	PROPN
fnp-3050	643	18	,	,	PUNCT
fnp-3050	643	19	boche	boche	PROPN
fnp-3050	643	20	d	d	PROPN
fnp-3050	643	21	(	(	PUNCT
fnp-3050	643	22	2018	2018	NUM
fnp-3050	643	23	)	)	PUNCT
fnp-3050	643	24	pyroglutamate	pyroglutamate	NOUN
fnp-3050	643	25	and	and	CCONJ
fnp-3050	643	26	isoaspartate	isoaspartate	ADJ
fnp-3050	643	27	modified	modify	VERB
fnp-3050	643	28	amyloid	amyloid	NOUN
fnp-3050	643	29	-	-	PUNCT
fnp-3050	643	30	beta	beta	NOUN
fnp-3050	643	31	in	in	ADP
fnp-3050	643	32	ageing	ageing	NOUN
fnp-3050	643	33	and	and	CCONJ
fnp-3050	643	34	alzheimer	alzheimer	NOUN
fnp-3050	643	35	's	's	PART
fnp-3050	643	36	disease	disease	NOUN
fnp-3050	643	37	.	.	PUNCT
fnp-3050	644	1	acta	acta	PROPN
fnp-3050	644	2	neuropathol	neuropathol	PROPN
fnp-3050	644	3	commun	commun	PROPN
fnp-3050	644	4	6:3	6:3	NUM
fnp-3050	644	5	65	65	NUM
fnp-3050	644	6	.	.	PUNCT
fnp-3050	645	1	nicoll	nicoll	PROPN
fnp-3050	645	2	ja	ja	PROPN
fnp-3050	645	3	,	,	PUNCT
fnp-3050	645	4	barton	barton	PROPN
fnp-3050	645	5	e	e	PROPN
fnp-3050	645	6	,	,	PUNCT
fnp-3050	645	7	boche	boche	PROPN
fnp-3050	645	8	d	d	PROPN
fnp-3050	645	9	,	,	PUNCT
fnp-3050	645	10	neal	neal	PROPN
fnp-3050	645	11	jw	jw	PROPN
fnp-3050	645	12	,	,	PUNCT
fnp-3050	645	13	ferrer	ferrer	PROPN
fnp-3050	645	14	i	i	PROPN
fnp-3050	645	15	,	,	PUNCT
fnp-3050	645	16	thompson	thompson	PROPN
fnp-3050	645	17	p	p	X
fnp-3050	645	18	,	,	PUNCT
fnp-3050	645	19	vlachouli	vlachouli	PROPN
fnp-3050	645	20	c	c	X
fnp-3050	645	21	,	,	PUNCT
fnp-3050	645	22	wilkinson	wilkinson	PROPN
fnp-3050	645	23	d	d	PROPN
fnp-3050	645	24	,	,	PUNCT
fnp-3050	645	25	bayer	bayer	PROPN
fnp-3050	645	26	a	a	NOUN
fnp-3050	645	27	,	,	PUNCT
fnp-3050	645	28	games	game	NOUN
fnp-3050	645	29	d	d	NOUN
fnp-3050	645	30	,	,	PUNCT
fnp-3050	645	31	seubert	seubert	VERB
fnp-3050	645	32	p	p	NOUN
fnp-3050	645	33	,	,	PUNCT
fnp-3050	645	34	schenk	schenk	PROPN
fnp-3050	645	35	d	d	PROPN
fnp-3050	645	36	,	,	PUNCT
fnp-3050	645	37	holmes	holmes	PROPN
fnp-3050	645	38	c	c	PROPN
fnp-3050	645	39	(	(	PUNCT
fnp-3050	645	40	2006	2006	NUM
fnp-3050	645	41	)	)	PUNCT
fnp-3050	645	42	abeta	abeta	NOUN
fnp-3050	645	43	species	specie	NOUN
fnp-3050	645	44	removal	removal	NOUN
fnp-3050	645	45	after	after	ADP
fnp-3050	645	46	abeta42	abeta42	NOUN
fnp-3050	645	47	immunization	immunization	NOUN
fnp-3050	645	48	.	.	PUNCT
fnp-3050	646	1	j	j	PROPN
fnp-3050	646	2	neuropathol	neuropathol	PROPN
fnp-3050	646	3	exp	exp	PROPN
fnp-3050	646	4	neurol	neurol	PROPN
fnp-3050	646	5	65:1040	65:1040	NOUN
fnp-3050	646	6	-	-	NUM
fnp-3050	646	7	1048	1048	NUM
fnp-3050	646	8	66	66	NUM
fnp-3050	646	9	.	.	PUNCT
fnp-3050	647	1	paasila	paasila	PROPN
fnp-3050	647	2	p	p	X
fnp-3050	647	3	,	,	PUNCT
fnp-3050	647	4	davies	davy	NOUN
fnp-3050	647	5	d	d	PROPN
fnp-3050	647	6	,	,	PUNCT
fnp-3050	647	7	sutherland	sutherland	PROPN
fnp-3050	647	8	g	g	PROPN
fnp-3050	647	9	,	,	PUNCT
fnp-3050	647	10	goldsbury	goldsbury	NOUN
fnp-3050	647	11	c	c	PROPN
fnp-3050	647	12	(	(	PUNCT
fnp-3050	647	13	2020	2020	NUM
fnp-3050	647	14	)	)	PUNCT
fnp-3050	647	15	clustering	clustering	NOUN
fnp-3050	647	16	of	of	ADP
fnp-3050	647	17	activated	activate	VERB
fnp-3050	647	18	microglia	microglia	NOUN
fnp-3050	647	19	occurs	occur	VERB
fnp-3050	647	20	before	before	ADP
fnp-3050	647	21	the	the	DET
fnp-3050	647	22	formation	formation	NOUN
fnp-3050	647	23	of	of	ADP
fnp-3050	647	24	dystrophic	dystrophic	ADJ
fnp-3050	647	25	neurites	neurite	NOUN
fnp-3050	647	26	in	in	ADP
fnp-3050	647	27	the	the	DET
fnp-3050	647	28	evolution	evolution	NOUN
fnp-3050	647	29	of	of	ADP
fnp-3050	647	30	abeta	abeta	PROPN
fnp-3050	647	31	plaques	plaque	NOUN
fnp-3050	647	32	in	in	ADP
fnp-3050	647	33	alzheimer	alzheimer	PROPN
fnp-3050	647	34	’s	’s	PART
fnp-3050	647	35	disease	disease	NOUN
fnp-3050	647	36	.	.	PUNCT
fnp-3050	648	1	free	free	ADJ
fnp-3050	648	2	neuropathol	neuropathol	NOUN
fnp-3050	648	3	1:20	1:20	NUM
fnp-3050	648	4	doi	doi	NOUN
fnp-3050	648	5	10.17879	10.17879	NUM
fnp-3050	648	6	/	/	SYM
fnp-3050	648	7	freeneuropathology-12020	freeneuropathology-12020	NOUN
fnp-3050	648	8	-	-	NOUN
fnp-3050	648	9	12845	12845	NUM
fnp-3050	648	10	67	67	NUM
fnp-3050	648	11	.	.	PUNCT
fnp-3050	649	1	reed	reed	NOUN
fnp-3050	649	2	-	-	PUNCT
fnp-3050	649	3	geaghan	geaghan	PROPN
fnp-3050	649	4	eg	eg	NOUN
fnp-3050	649	5	,	,	PUNCT
fnp-3050	649	6	croxford	croxford	PROPN
fnp-3050	649	7	al	al	PROPN
fnp-3050	649	8	,	,	PUNCT
fnp-3050	649	9	becher	becher	PROPN
fnp-3050	649	10	b	b	NUM
fnp-3050	649	11	,	,	PUNCT
fnp-3050	649	12	landreth	landreth	PROPN
fnp-3050	649	13	ge	ge	PROPN
fnp-3050	649	14	(	(	PUNCT
fnp-3050	649	15	2020	2020	NUM
fnp-3050	649	16	)	)	PUNCT
fnp-3050	649	17	plaque	plaque	NOUN
fnp-3050	649	18	-	-	PUNCT
fnp-3050	649	19	associated	associate	VERB
fnp-3050	649	20	myeloid	myeloid	ADJ
fnp-3050	649	21	cells	cell	NOUN
fnp-3050	649	22	derive	derive	VERB
fnp-3050	649	23	from	from	ADP
fnp-3050	649	24	resident	resident	ADJ
fnp-3050	649	25	microglia	microglia	NOUN
fnp-3050	649	26	in	in	ADP
fnp-3050	649	27	an	an	DET
fnp-3050	649	28	alzheimer	alzheimer	NOUN
fnp-3050	649	29	's	's	PART
fnp-3050	649	30	disease	disease	NOUN
fnp-3050	649	31	model	model	NOUN
fnp-3050	649	32	.	.	PUNCT
fnp-3050	650	1	j	j	PROPN
fnp-3050	650	2	exp	exp	NOUN
fnp-3050	650	3	med	me	VERB
fnp-3050	650	4	217	217	NUM
fnp-3050	650	5	68	68	NUM
fnp-3050	650	6	.	.	PUNCT
fnp-3050	651	1	yeh	yeh	PROPN
fnp-3050	651	2	fl	fl	PROPN
fnp-3050	651	3	,	,	PUNCT
fnp-3050	651	4	hansen	hansen	PROPN
fnp-3050	651	5	dv	dv	PROPN
fnp-3050	651	6	,	,	PUNCT
fnp-3050	651	7	sheng	sheng	PROPN
fnp-3050	651	8	m	m	PROPN
fnp-3050	651	9	(	(	PUNCT
fnp-3050	651	10	2017	2017	NUM
fnp-3050	651	11	)	)	PUNCT
fnp-3050	651	12	trem2	trem2	NOUN
fnp-3050	651	13	,	,	PUNCT
fnp-3050	651	14	microglia	microglia	ADJ
fnp-3050	651	15	,	,	PUNCT
fnp-3050	651	16	and	and	CCONJ
fnp-3050	651	17	neurodegenerative	neurodegenerative	ADJ
fnp-3050	651	18	diseases	disease	NOUN
fnp-3050	651	19	.	.	PUNCT
fnp-3050	652	1	trends	trend	NOUN
fnp-3050	652	2	mol	mol	ADP
fnp-3050	652	3	med	med	PROPN
fnp-3050	652	4	23:512	23:512	NUM
fnp-3050	652	5	-	-	SYM
fnp-3050	652	6	533	533	NUM
fnp-3050	652	7	69	69	NUM
fnp-3050	652	8	.	.	PUNCT
fnp-3050	653	1	han	han	PROPN
fnp-3050	653	2	s	s	PROPN
fnp-3050	653	3	,	,	PUNCT
fnp-3050	653	4	kollmer	kollmer	PROPN
fnp-3050	653	5	m	m	PROPN
fnp-3050	653	6	,	,	PUNCT
fnp-3050	653	7	markx	markx	NOUN
fnp-3050	653	8	d	d	NOUN
fnp-3050	653	9	,	,	PUNCT
fnp-3050	653	10	claus	claus	PROPN
fnp-3050	653	11	s	s	PROPN
fnp-3050	653	12	,	,	PUNCT
fnp-3050	653	13	walther	walther	NOUN
fnp-3050	653	14	p	p	NOUN
fnp-3050	653	15	,	,	PUNCT
fnp-3050	653	16	fändrich	fändrich	NOUN
fnp-3050	653	17	m	m	VERB
fnp-3050	653	18	(	(	PUNCT
fnp-3050	653	19	2017	2017	NUM
fnp-3050	653	20	)	)	PUNCT
fnp-3050	653	21	amyloid	amyloid	NOUN
fnp-3050	653	22	plaque	plaque	NOUN
fnp-3050	653	23	structure	structure	NOUN
fnp-3050	653	24	and	and	CCONJ
fnp-3050	653	25	cell	cell	NOUN
fnp-3050	653	26	surface	surface	NOUN
fnp-3050	653	27	interactions	interaction	NOUN
fnp-3050	653	28	of	of	ADP
fnp-3050	653	29	beta	beta	NOUN
fnp-3050	653	30	-	-	PUNCT
fnp-3050	653	31	amyloid	amyloid	NOUN
fnp-3050	653	32	fibrils	fibril	NOUN
fnp-3050	653	33	revealed	reveal	VERB
fnp-3050	653	34	by	by	ADP
fnp-3050	653	35	electron	electron	NOUN
fnp-3050	653	36	tomography	tomography	NOUN
fnp-3050	653	37	.	.	PUNCT
fnp-3050	654	1	sci	sci	PROPN
fnp-3050	654	2	rep	rep	PROPN
fnp-3050	655	1	7:43577	7:43577	PROPN
fnp-3050	655	2	70	70	NUM
fnp-3050	655	3	.	.	PUNCT
fnp-3050	656	1	boon	boon	PROPN
fnp-3050	656	2	bdc	bdc	PROPN
fnp-3050	656	3	,	,	PUNCT
fnp-3050	656	4	bulk	bulk	NOUN
fnp-3050	656	5	m	m	PROPN
fnp-3050	656	6	,	,	PUNCT
fnp-3050	656	7	jonker	jonker	PROPN
fnp-3050	656	8	aj	aj	PROPN
fnp-3050	656	9	,	,	PUNCT
fnp-3050	656	10	morrema	morrema	NOUN
fnp-3050	656	11	thj	thj	PROPN
fnp-3050	656	12	,	,	PUNCT
fnp-3050	656	13	van	van	PROPN
fnp-3050	656	14	den	den	PROPN
fnp-3050	656	15	berg	berg	PROPN
fnp-3050	656	16	e	e	PROPN
fnp-3050	656	17	,	,	PUNCT
fnp-3050	656	18	popovic	popovic	PROPN
fnp-3050	656	19	m	m	PROPN
fnp-3050	656	20	,	,	PUNCT
fnp-3050	656	21	walter	walter	PROPN
fnp-3050	656	22	j	j	PROPN
fnp-3050	656	23	,	,	PUNCT
fnp-3050	656	24	kumar	kumar	PROPN
fnp-3050	656	25	s	s	PROPN
fnp-3050	656	26	,	,	PUNCT
fnp-3050	656	27	van	van	PROPN
fnp-3050	656	28	der	der	NOUN
fnp-3050	656	29	lee	lee	PROPN
fnp-3050	656	30	sj	sj	PROPN
fnp-3050	656	31	,	,	PUNCT
fnp-3050	656	32	holstege	holstege	NOUN
fnp-3050	656	33	h	h	NOUN
fnp-3050	656	34	,	,	PUNCT
fnp-3050	656	35	zhu	zhu	PROPN
fnp-3050	656	36	x	x	PRON
fnp-3050	656	37	,	,	PUNCT
fnp-3050	656	38	van	van	PROPN
fnp-3050	656	39	nostrand	nostrand	PROPN
fnp-3050	656	40	we	we	PRON
fnp-3050	656	41	,	,	PUNCT
fnp-3050	656	42	natté	natté	NOUN
fnp-3050	656	43	r	r	NOUN
fnp-3050	656	44	,	,	PUNCT
fnp-3050	656	45	van	van	PROPN
fnp-3050	656	46	der	der	PROPN
fnp-3050	656	47	weerd	weerd	PROPN
fnp-3050	656	48	l	l	PROPN
fnp-3050	656	49	,	,	PUNCT
fnp-3050	656	50	bouwman	bouwman	NOUN
fnp-3050	656	51	fh	fh	PROPN
fnp-3050	656	52	,	,	PUNCT
fnp-3050	656	53	van	van	PROPN
fnp-3050	656	54	de	de	PROPN
fnp-3050	656	55	berg	berg	PROPN
fnp-3050	656	56	wdj	wdj	PROPN
fnp-3050	656	57	,	,	PUNCT
fnp-3050	656	58	rozemuller	rozemuller	PROPN
fnp-3050	656	59	ajm	ajm	PROPN
fnp-3050	656	60	,	,	PUNCT
fnp-3050	656	61	hoozemans	hoozemans	PROPN
fnp-3050	656	62	jjm	jjm	PROPN
fnp-3050	656	63	(	(	PUNCT
fnp-3050	656	64	2020	2020	NUM
fnp-3050	656	65	)	)	PUNCT
fnp-3050	656	66	the	the	DET
fnp-3050	656	67	coarse	coarse	ADV
fnp-3050	656	68	-	-	PUNCT
fnp-3050	656	69	grained	grain	VERB
fnp-3050	656	70	plaque	plaque	NOUN
fnp-3050	656	71	:	:	PUNCT
fnp-3050	656	72	a	a	DET
fnp-3050	656	73	divergent	divergent	ADJ
fnp-3050	656	74	abeta	abeta	NOUN
fnp-3050	656	75	plaque	plaque	NOUN
fnp-3050	656	76	-	-	PUNCT
fnp-3050	656	77	type	type	NOUN
fnp-3050	656	78	in	in	ADP
fnp-3050	656	79	early	early	ADJ
fnp-3050	656	80	-	-	PUNCT
fnp-3050	656	81	onset	onset	NOUN
fnp-3050	656	82	alzheimer	alzheimer	NOUN
fnp-3050	656	83	's	's	PART
fnp-3050	656	84	disease	disease	NOUN
fnp-3050	656	85	.	.	PUNCT
fnp-3050	657	1	acta	acta	PROPN
fnp-3050	657	2	neuropathol	neuropathol	PROPN
fnp-3050	657	3	online	online	PROPN
fnp-3050	657	4	sep	sep	PROPN
fnp-3050	657	5	14	14	NUM
fnp-3050	657	6	:	:	PUNCT
fnp-3050	657	7	doi	doi	NOUN
fnp-3050	657	8	:	:	PUNCT
fnp-3050	657	9	10.1007	10.1007	NUM
fnp-3050	657	10	/	/	SYM
fnp-3050	657	11	s00401	s00401	NOUN
fnp-3050	657	12	-	-	PUNCT
fnp-3050	657	13	00020	00020	NUM
fnp-3050	657	14	-	-	PUNCT
fnp-3050	657	15	02198	02198	NUM
fnp-3050	657	16	-	-	PUNCT
fnp-3050	657	17	00408	00408	NUM
fnp-3050	657	18	71	71	NUM
fnp-3050	657	19	.	.	PUNCT
fnp-3050	658	1	attems	attem	VERB
fnp-3050	658	2	j	j	PROPN
fnp-3050	658	3	,	,	PUNCT
fnp-3050	658	4	jellinger	jellinger	PROPN
fnp-3050	658	5	ka	ka	PROPN
fnp-3050	658	6	(	(	PUNCT
fnp-3050	658	7	2013	2013	NUM
fnp-3050	658	8	)	)	PUNCT
fnp-3050	658	9	neuropathology	neuropathology	NOUN
fnp-3050	658	10	.	.	PUNCT
fnp-3050	659	1	in	in	ADP
fnp-3050	659	2	:	:	PUNCT
fnp-3050	659	3	dening	dening	PROPN
fnp-3050	659	4	t	t	PROPN
fnp-3050	659	5	,	,	PUNCT
fnp-3050	659	6	thomas	thomas	PROPN
fnp-3050	659	7	a	a	DET
fnp-3050	659	8	(	(	PUNCT
fnp-3050	659	9	eds	ed	NOUN
fnp-3050	659	10	)	)	PUNCT
fnp-3050	659	11	oxford	oxford	ADJ
fnp-3050	659	12	textbook	textbook	NOUN
fnp-3050	659	13	of	of	ADP
fnp-3050	659	14	old	old	ADJ
fnp-3050	659	15	age	age	NOUN
fnp-3050	659	16	psychiatry	psychiatry	NOUN
fnp-3050	659	17	(	(	PUNCT
fnp-3050	659	18	2	2	NUM
fnp-3050	659	19	ed	ed	NOUN
fnp-3050	659	20	.	.	PUNCT
fnp-3050	659	21	)	)	PUNCT
fnp-3050	659	22	.	.	PUNCT
fnp-3050	660	1	oxford	oxford	PROPN
fnp-3050	660	2	univ	univ	PROPN
fnp-3050	660	3	.	.	PUNCT
fnp-3050	661	1	press	press	PROPN
fnp-3050	661	2	oxford	oxford	PROPN
fnp-3050	661	3	,	,	PUNCT
fnp-3050	661	4	uk	uk	PROPN
fnp-3050	661	5	,	,	PUNCT
fnp-3050	661	6	pp	pp	ADV
fnp-3050	661	7	87	87	NUM
fnp-3050	661	8	-	-	SYM
fnp-3050	661	9	105	105	NUM
fnp-3050	661	10	,	,	PUNCT
fnp-3050	661	11	doi	doi	NOUN
fnp-3050	661	12	:	:	PUNCT
fnp-3050	661	13	110.1093	110.1093	NUM
fnp-3050	661	14	/	/	SYM
fnp-3050	661	15	med/9780199644957.9780199644003.9780199640006	med/9780199644957.9780199644003.9780199640006	ADJ
fnp-3050	661	16	72	72	NUM
fnp-3050	661	17	.	.	PUNCT
fnp-3050	662	1	oide	oide	PROPN
fnp-3050	662	2	t	t	PROPN
fnp-3050	662	3	,	,	PUNCT
fnp-3050	662	4	kinoshita	kinoshita	PROPN
fnp-3050	662	5	t	t	PROPN
fnp-3050	662	6	,	,	PUNCT
fnp-3050	662	7	arima	arima	PROPN
fnp-3050	662	8	k	k	PROPN
fnp-3050	662	9	(	(	PUNCT
fnp-3050	662	10	2006	2006	NUM
fnp-3050	662	11	)	)	PUNCT
fnp-3050	662	12	regression	regression	NOUN
fnp-3050	662	13	stage	stage	NOUN
fnp-3050	662	14	senile	senile	ADJ
fnp-3050	662	15	plaques	plaque	NOUN
fnp-3050	662	16	in	in	ADP
fnp-3050	662	17	the	the	DET
fnp-3050	662	18	natural	natural	ADJ
fnp-3050	662	19	course	course	NOUN
fnp-3050	662	20	of	of	ADP
fnp-3050	662	21	alzheimer	alzheimer	PROPN
fnp-3050	662	22	's	's	PART
fnp-3050	662	23	disease	disease	NOUN
fnp-3050	662	24	.	.	PUNCT
fnp-3050	663	1	neuropathol	neuropathol	PROPN
fnp-3050	663	2	appl	appl	PROPN
fnp-3050	663	3	neurobiol	neurobiol	PROPN
fnp-3050	663	4	32:539	32:539	NUM
fnp-3050	663	5	-	-	SYM
fnp-3050	663	6	556	556	NUM
fnp-3050	663	7	73	73	NUM
fnp-3050	663	8	.	.	PUNCT
fnp-3050	664	1	boche	boche	PROPN
fnp-3050	664	2	d	d	PROPN
fnp-3050	664	3	,	,	PUNCT
fnp-3050	664	4	nicoll	nicoll	PROPN
fnp-3050	664	5	jar	jar	PROPN
fnp-3050	664	6	(	(	PUNCT
fnp-3050	664	7	2020	2020	NUM
fnp-3050	664	8	)	)	PUNCT
fnp-3050	664	9	understanding	understanding	NOUN
fnp-3050	664	10	cause	cause	NOUN
fnp-3050	664	11	and	and	CCONJ
fnp-3050	664	12	effect	effect	NOUN
fnp-3050	664	13	in	in	ADP
fnp-3050	664	14	alzheimer	alzheimer	PROPN
fnp-3050	664	15	's	's	PART
fnp-3050	664	16	pathophysiology	pathophysiology	NOUN
fnp-3050	664	17	:	:	PUNCT
fnp-3050	664	18	implications	implication	NOUN
fnp-3050	664	19	for	for	ADP
fnp-3050	664	20	clinical	clinical	ADJ
fnp-3050	664	21	trials	trial	NOUN
fnp-3050	664	22	.	.	PUNCT
fnp-3050	665	1	neuropathol	neuropathol	PROPN
fnp-3050	665	2	appl	appl	PROPN
fnp-3050	665	3	neurobiol	neurobiol	PROPN
fnp-3050	665	4	jul	jul	PROPN
fnp-3050	665	5	8	8	NUM
fnp-3050	665	6	:	:	PUNCT
fnp-3050	665	7	https://doi.org/10.1111	https://doi.org/10.1111	PROPN
fnp-3050	665	8	/	/	SYM
fnp-3050	665	9	nan.12642	nan.12642	ADP
fnp-3050	665	10	74	74	NUM
fnp-3050	665	11	.	.	PUNCT
fnp-3050	666	1	harris	harris	PROPN
fnp-3050	666	2	ja	ja	PROPN
fnp-3050	666	3	,	,	PUNCT
fnp-3050	666	4	devidze	devidze	NOUN
fnp-3050	666	5	n	n	CCONJ
fnp-3050	666	6	,	,	PUNCT
fnp-3050	666	7	verret	verret	PROPN
fnp-3050	666	8	l	l	NOUN
fnp-3050	666	9	,	,	PUNCT
fnp-3050	666	10	ho	ho	PROPN
fnp-3050	666	11	k	k	PROPN
fnp-3050	666	12	,	,	PUNCT
fnp-3050	666	13	halabisky	halabisky	NOUN
fnp-3050	666	14	b	b	NOUN
fnp-3050	666	15	,	,	PUNCT
fnp-3050	666	16	thwin	thwin	PROPN
fnp-3050	666	17	mt	mt	PROPN
fnp-3050	666	18	,	,	PUNCT
fnp-3050	666	19	kim	kim	PROPN
fnp-3050	666	20	d	d	PROPN
fnp-3050	666	21	,	,	PUNCT
fnp-3050	666	22	hamto	hamto	PROPN
fnp-3050	666	23	p	p	X
fnp-3050	666	24	,	,	PUNCT
fnp-3050	666	25	lo	lo	PROPN
fnp-3050	666	26	i	i	PROPN
fnp-3050	666	27	,	,	PUNCT
fnp-3050	666	28	yu	yu	PROPN
fnp-3050	666	29	gq	gq	PROPN
fnp-3050	666	30	,	,	PUNCT
fnp-3050	666	31	palop	palop	PROPN
fnp-3050	666	32	jj	jj	PROPN
fnp-3050	666	33	,	,	PUNCT
fnp-3050	666	34	masliah	masliah	PROPN
fnp-3050	666	35	e	e	PROPN
fnp-3050	666	36	,	,	PUNCT
fnp-3050	666	37	mucke	mucke	PROPN
fnp-3050	666	38	l	l	PROPN
fnp-3050	666	39	(	(	PUNCT
fnp-3050	666	40	2010	2010	NUM
fnp-3050	666	41	)	)	PUNCT
fnp-3050	666	42	transsynaptic	transsynaptic	ADJ
fnp-3050	666	43	progression	progression	NOUN
fnp-3050	666	44	of	of	ADP
fnp-3050	666	45	amyloid	amyloid	NOUN
fnp-3050	666	46	-	-	PUNCT
fnp-3050	666	47	beta	beta	NOUN
fnp-3050	666	48	-	-	PUNCT
fnp-3050	666	49	induced	induce	VERB
fnp-3050	666	50	neuronal	neuronal	ADJ
fnp-3050	666	51	dysfunction	dysfunction	NOUN
fnp-3050	666	52	within	within	ADP
fnp-3050	666	53	the	the	DET
fnp-3050	666	54	entorhinal	entorhinal	ADJ
fnp-3050	666	55	-	-	PUNCT
fnp-3050	666	56	hippocampal	hippocampal	ADJ
fnp-3050	666	57	network	network	NOUN
fnp-3050	666	58	.	.	PUNCT
fnp-3050	667	1	neuron	neuron	PROPN
fnp-3050	667	2	68:428	68:428	PROPN
fnp-3050	667	3	-	-	PUNCT
fnp-3050	667	4	441	441	NUM
fnp-3050	667	5	75	75	NUM
fnp-3050	667	6	.	.	PUNCT
fnp-3050	668	1	yamamoto	yamamoto	PROPN
fnp-3050	668	2	k	k	PROPN
fnp-3050	668	3	,	,	PUNCT
fnp-3050	668	4	tanei	tanei	PROPN
fnp-3050	668	5	zi	zi	PROPN
fnp-3050	668	6	,	,	PUNCT
fnp-3050	668	7	hashimoto	hashimoto	NOUN
fnp-3050	668	8	t	t	PROPN
fnp-3050	668	9	,	,	PUNCT
fnp-3050	668	10	wakabayashi	wakabayashi	PROPN
fnp-3050	668	11	t	t	PROPN
fnp-3050	668	12	,	,	PUNCT
fnp-3050	668	13	okuno	okuno	PROPN
fnp-3050	668	14	h	h	PROPN
fnp-3050	668	15	,	,	PUNCT
fnp-3050	668	16	naka	naka	PROPN
fnp-3050	668	17	y	y	PROPN
fnp-3050	668	18	,	,	PUNCT
fnp-3050	668	19	yizhar	yizhar	PROPN
fnp-3050	668	20	o	o	NOUN
fnp-3050	668	21	,	,	PUNCT
fnp-3050	668	22	fenno	fenno	NOUN
fnp-3050	668	23	le	le	X
fnp-3050	668	24	,	,	PUNCT
fnp-3050	668	25	fukayama	fukayama	NOUN
fnp-3050	668	26	m	m	PROPN
fnp-3050	668	27	,	,	PUNCT
fnp-3050	668	28	bito	bito	PROPN
fnp-3050	668	29	h	h	PROPN
fnp-3050	668	30	,	,	PUNCT
fnp-3050	668	31	cirrito	cirrito	PROPN
fnp-3050	668	32	jr	jr	PROPN
fnp-3050	668	33	,	,	PUNCT
fnp-3050	668	34	holtzman	holtzman	ADJ
fnp-3050	668	35	dm	dm	PROPN
fnp-3050	668	36	,	,	PUNCT
fnp-3050	668	37	deisseroth	deisseroth	PROPN
fnp-3050	668	38	k	k	NOUN
fnp-3050	668	39	,	,	PUNCT
fnp-3050	668	40	iwatsubo	iwatsubo	PROPN
fnp-3050	668	41	t	t	PROPN
fnp-3050	668	42	(	(	PUNCT
fnp-3050	668	43	2015	2015	NUM
fnp-3050	668	44	)	)	PUNCT
fnp-3050	668	45	chronic	chronic	ADJ
fnp-3050	668	46	optogenetic	optogenetic	ADJ
fnp-3050	668	47	activation	activation	NOUN
fnp-3050	668	48	augments	augment	VERB
fnp-3050	668	49	abeta	abeta	PROPN
fnp-3050	668	50	pathology	pathology	NOUN
fnp-3050	668	51	in	in	ADP
fnp-3050	668	52	a	a	DET
fnp-3050	668	53	mouse	mouse	NOUN
fnp-3050	668	54	model	model	NOUN
fnp-3050	668	55	of	of	ADP
fnp-3050	668	56	alzheimer	alzheimer	PROPN
fnp-3050	668	57	disease	disease	PROPN
fnp-3050	668	58	.	.	PUNCT
fnp-3050	669	1	cell	cell	NOUN
fnp-3050	669	2	rep	rep	PROPN
fnp-3050	669	3	11:859	11:859	NUM
fnp-3050	669	4	-	-	SYM
fnp-3050	669	5	865	865	NUM
fnp-3050	669	6	76	76	NUM
fnp-3050	669	7	.	.	PUNCT
fnp-3050	670	1	reiss	reiss	PROPN
fnp-3050	670	2	ab	ab	PROPN
fnp-3050	670	3	,	,	PUNCT
fnp-3050	670	4	arain	arain	PROPN
fnp-3050	670	5	ha	ha	INTJ
fnp-3050	670	6	,	,	PUNCT
fnp-3050	670	7	stecker	stecker	NOUN
fnp-3050	670	8	mm	mm	PROPN
fnp-3050	670	9	,	,	PUNCT
fnp-3050	670	10	siegart	siegart	NOUN
fnp-3050	670	11	nm	nm	PROPN
fnp-3050	670	12	,	,	PUNCT
fnp-3050	670	13	kasselman	kasselman	NOUN
fnp-3050	670	14	lj	lj	PROPN
fnp-3050	670	15	(	(	PUNCT
fnp-3050	670	16	2018	2018	NUM
fnp-3050	670	17	)	)	PUNCT
fnp-3050	670	18	amyloid	amyloid	NOUN
fnp-3050	670	19	toxicity	toxicity	NOUN
fnp-3050	670	20	in	in	ADP
fnp-3050	670	21	alzheimer	alzheimer	PROPN
fnp-3050	670	22	's	's	PART
fnp-3050	670	23	disease	disease	NOUN
fnp-3050	670	24	.	.	PUNCT
fnp-3050	671	1	rev	rev	PROPN
fnp-3050	671	2	neurosci	neurosci	PROPN
fnp-3050	671	3	29:613	29:613	NUM
fnp-3050	671	4	-	-	SYM
fnp-3050	671	5	627	627	NUM
fnp-3050	671	6	77	77	NUM
fnp-3050	671	7	.	.	PUNCT
fnp-3050	671	8	yu	yu	PROPN
fnp-3050	672	1	l	l	NOUN
fnp-3050	672	2	,	,	PUNCT
fnp-3050	672	3	petyuk	petyuk	PROPN
fnp-3050	672	4	va	va	PROPN
fnp-3050	672	5	,	,	PUNCT
fnp-3050	672	6	tasaki	tasaki	PROPN
fnp-3050	672	7	s	s	PROPN
fnp-3050	672	8	,	,	PUNCT
fnp-3050	672	9	boyle	boyle	PROPN
fnp-3050	672	10	pa	pa	PROPN
fnp-3050	672	11	,	,	PUNCT
fnp-3050	672	12	gaiteri	gaiteri	ADJ
fnp-3050	672	13	c	c	PROPN
fnp-3050	672	14	,	,	PUNCT
fnp-3050	672	15	schneider	schneider	PROPN
fnp-3050	672	16	ja	ja	PROPN
fnp-3050	672	17	,	,	PUNCT
fnp-3050	672	18	de	de	PROPN
fnp-3050	672	19	jager	jager	PROPN
fnp-3050	672	20	pl	pl	PROPN
fnp-3050	672	21	,	,	PUNCT
fnp-3050	672	22	bennett	bennett	PROPN
fnp-3050	672	23	da	da	PROPN
fnp-3050	672	24	(	(	PUNCT
fnp-3050	672	25	2019	2019	NUM
fnp-3050	672	26	)	)	PUNCT
fnp-3050	672	27	association	association	NOUN
fnp-3050	672	28	of	of	ADP
fnp-3050	672	29	cortical	cortical	ADJ
fnp-3050	672	30	beta	beta	NOUN
fnp-3050	672	31	-	-	PUNCT
fnp-3050	672	32	amyloid	amyloid	NOUN
fnp-3050	672	33	protein	protein	NOUN
fnp-3050	672	34	in	in	ADP
fnp-3050	672	35	the	the	DET
fnp-3050	672	36	absence	absence	NOUN
fnp-3050	672	37	of	of	ADP
fnp-3050	672	38	insoluble	insoluble	ADJ
fnp-3050	672	39	deposits	deposit	NOUN
fnp-3050	672	40	with	with	ADP
fnp-3050	672	41	alzheimer	alzheimer	PROPN
fnp-3050	672	42	disease	disease	PROPN
fnp-3050	672	43	.	.	PUNCT
fnp-3050	673	1	jama	jama	PROPN
fnp-3050	673	2	neurol	neurol	PROPN
fnp-3050	673	3	76:818	76:818	PROPN
fnp-3050	673	4	-	-	SYM
fnp-3050	673	5	826	826	NUM
fnp-3050	673	6	78	78	NUM
fnp-3050	673	7	.	.	PUNCT
fnp-3050	674	1	katzmarski	katzmarski	PROPN
fnp-3050	674	2	n	n	CCONJ
fnp-3050	674	3	,	,	PUNCT
fnp-3050	674	4	ziegler	ziegler	NOUN
fnp-3050	674	5	-	-	NOUN
fnp-3050	674	6	waldkirch	waldkirch	NOUN
fnp-3050	674	7	s	s	PROPN
fnp-3050	674	8	,	,	PUNCT
fnp-3050	674	9	scheffler	scheffler	NOUN
fnp-3050	674	10	n	n	CCONJ
fnp-3050	674	11	,	,	PUNCT
fnp-3050	674	12	witt	witt	PROPN
fnp-3050	674	13	c	c	PROPN
fnp-3050	674	14	,	,	PUNCT
fnp-3050	674	15	abou	abou	PROPN
fnp-3050	674	16	-	-	PUNCT
fnp-3050	674	17	ajram	ajram	PROPN
fnp-3050	674	18	c	c	PROPN
fnp-3050	674	19	,	,	PUNCT
fnp-3050	674	20	nuscher	nuscher	PROPN
fnp-3050	674	21	b	b	NOUN
fnp-3050	674	22	,	,	PUNCT
fnp-3050	674	23	prinz	prinz	PROPN
fnp-3050	674	24	m	m	PROPN
fnp-3050	674	25	,	,	PUNCT
fnp-3050	674	26	haass	haass	VERB
fnp-3050	674	27	c	c	NOUN
fnp-3050	674	28	,	,	PUNCT
fnp-3050	674	29	meyer	meyer	PROPN
fnp-3050	674	30	-	-	PUNCT
fnp-3050	674	31	luehmann	luehmann	PROPN
fnp-3050	674	32	m	m	PROPN
fnp-3050	674	33	(	(	PUNCT
fnp-3050	674	34	2020	2020	NUM
fnp-3050	674	35	)	)	PUNCT
fnp-3050	674	36	abeta	abeta	PROPN
fnp-3050	674	37	oligomers	oligomer	NOUN
fnp-3050	674	38	trigger	trigger	NOUN
fnp-3050	674	39	and	and	CCONJ
fnp-3050	674	40	accelerate	accelerate	VERB
fnp-3050	674	41	abeta	abeta	NOUN
fnp-3050	674	42	seeding	seeding	NOUN
fnp-3050	674	43	.	.	PUNCT
fnp-3050	675	1	brain	brain	NOUN
fnp-3050	675	2	pathol	pathol	NOUN
fnp-3050	675	3	30:36	30:36	NUM
fnp-3050	675	4	-	-	SYM
fnp-3050	675	5	45	45	NUM
fnp-3050	675	6	79	79	NUM
fnp-3050	675	7	.	.	PUNCT
fnp-3050	676	1	thal	thal	PROPN
fnp-3050	676	2	dr	dr	PROPN
fnp-3050	676	3	,	,	PUNCT
fnp-3050	676	4	rub	rub	PROPN
fnp-3050	676	5	u	u	NOUN
fnp-3050	676	6	,	,	PUNCT
fnp-3050	676	7	orantes	orantes	PROPN
fnp-3050	676	8	m	m	PROPN
fnp-3050	676	9	,	,	PUNCT
fnp-3050	676	10	braak	braak	PROPN
fnp-3050	676	11	h	h	PROPN
fnp-3050	676	12	(	(	PUNCT
fnp-3050	676	13	2002	2002	NUM
fnp-3050	676	14	)	)	PUNCT
fnp-3050	676	15	phases	phase	NOUN
fnp-3050	676	16	of	of	ADP
fnp-3050	676	17	a	a	DET
fnp-3050	676	18	beta	beta	NOUN
fnp-3050	676	19	-	-	PUNCT
fnp-3050	676	20	deposition	deposition	NOUN
fnp-3050	676	21	in	in	ADP
fnp-3050	676	22	the	the	DET
fnp-3050	676	23	human	human	ADJ
fnp-3050	676	24	brain	brain	NOUN
fnp-3050	676	25	and	and	CCONJ
fnp-3050	676	26	its	its	PRON
fnp-3050	676	27	relevance	relevance	NOUN
fnp-3050	676	28	for	for	ADP
fnp-3050	676	29	the	the	DET
fnp-3050	676	30	development	development	NOUN
fnp-3050	676	31	of	of	ADP
fnp-3050	676	32	ad	ad	NOUN
fnp-3050	676	33	.	.	PUNCT
fnp-3050	677	1	neurology	neurology	NOUN
fnp-3050	677	2	58:1791	58:1791	NUM
fnp-3050	677	3	-	-	SYM
fnp-3050	677	4	1800	1800	NUM
fnp-3050	677	5	80	80	NUM
fnp-3050	677	6	.	.	PUNCT
fnp-3050	678	1	walker	walker	PROPN
fnp-3050	678	2	lc	lc	PROPN
fnp-3050	678	3	(	(	PUNCT
fnp-3050	678	4	2020	2020	NUM
fnp-3050	678	5	)	)	PUNCT
fnp-3050	678	6	aß	aß	ADP
fnp-3050	678	7	plaques	plaque	NOUN
fnp-3050	678	8	.	.	PUNCT
fnp-3050	679	1	free	free	ADJ
fnp-3050	679	2	neuropathol	neuropathol	NOUN
fnp-3050	679	3	1:31	1:31	NUM
fnp-3050	679	4	,	,	PUNCT
fnp-3050	679	5	doi	doi	X
fnp-3050	679	6	10.17879	10.17879	NUM
fnp-3050	679	7	/	/	SYM
fnp-3050	679	8	freeneuropathology-12020	freeneuropathology-12020	NOUN
fnp-3050	679	9	-	-	PUNCT
fnp-3050	679	10	13025	13025	NUM
fnp-3050	679	11	81	81	NUM
fnp-3050	679	12	.	.	PUNCT
fnp-3050	680	1	thal	thal	PROPN
fnp-3050	680	2	dr	dr	PROPN
fnp-3050	680	3	,	,	PUNCT
fnp-3050	680	4	ronisz	ronisz	NOUN
fnp-3050	680	5	a	a	DET
fnp-3050	680	6	,	,	PUNCT
fnp-3050	680	7	tousseyn	tousseyn	ADJ
fnp-3050	680	8	t	t	PROPN
fnp-3050	680	9	,	,	PUNCT
fnp-3050	680	10	rijal	rijal	VERB
fnp-3050	680	11	upadhaya	upadhaya	NOUN
fnp-3050	680	12	a	a	PRON
fnp-3050	680	13	,	,	PUNCT
fnp-3050	680	14	balakrishnan	balakrishnan	PROPN
fnp-3050	680	15	k	k	NOUN
fnp-3050	680	16	,	,	PUNCT
fnp-3050	680	17	vandenberghe	vandenberghe	PROPN
fnp-3050	680	18	r	r	PROPN
fnp-3050	680	19	,	,	PUNCT
fnp-3050	680	20	vandenbulcke	vandenbulcke	PROPN
fnp-3050	680	21	m	m	PROPN
fnp-3050	680	22	,	,	PUNCT
fnp-3050	680	23	von	von	PROPN
fnp-3050	680	24	arnim	arnim	PROPN
fnp-3050	680	25	caf	caf	PROPN
fnp-3050	680	26	,	,	PUNCT
fnp-3050	680	27	otto	otto	PROPN
fnp-3050	680	28	m	m	PROPN
fnp-3050	680	29	,	,	PUNCT
fnp-3050	680	30	beach	beach	PROPN
fnp-3050	680	31	tg	tg	PROPN
fnp-3050	680	32	,	,	PUNCT
fnp-3050	680	33	lilja	lilja	PROPN
fnp-3050	680	34	j	j	PROPN
fnp-3050	680	35	,	,	PUNCT
fnp-3050	680	36	heurling	heurle	VERB
fnp-3050	680	37	k	k	PROPN
fnp-3050	680	38	,	,	PUNCT
fnp-3050	680	39	chakrabarty	chakrabarty	PROPN
fnp-3050	680	40	a	a	X
fnp-3050	680	41	,	,	PUNCT
fnp-3050	680	42	ismail	ismail	PROPN
fnp-3050	680	43	a	a	PRON
fnp-3050	680	44	,	,	PUNCT
fnp-3050	680	45	buckley	buckley	PROPN
fnp-3050	680	46	c	c	PROPN
fnp-3050	680	47	,	,	PUNCT
fnp-3050	680	48	smith	smith	PROPN
fnp-3050	680	49	apl	apl	PROPN
fnp-3050	680	50	,	,	PUNCT
fnp-3050	680	51	kumar	kumar	PROPN
fnp-3050	680	52	s	s	PROPN
fnp-3050	680	53	,	,	PUNCT
fnp-3050	680	54	farrar	farrar	PROPN
fnp-3050	680	55	g	g	PROPN
fnp-3050	680	56	,	,	PUNCT
fnp-3050	680	57	walter	walter	PROPN
fnp-3050	680	58	j	j	PROPN
fnp-3050	680	59	(	(	PUNCT
fnp-3050	680	60	2019	2019	NUM
fnp-3050	680	61	)	)	PUNCT
fnp-3050	680	62	different	different	ADJ
fnp-3050	680	63	aspects	aspect	NOUN
fnp-3050	680	64	of	of	ADP
fnp-3050	680	65	alzheimer	alzheimer	PROPN
fnp-3050	680	66	's	's	PART
fnp-3050	680	67	disease	disease	NOUN
fnp-3050	680	68	-	-	PUNCT
fnp-3050	680	69	related	relate	VERB
fnp-3050	680	70	amyloid	amyloid	NOUN
fnp-3050	680	71	beta	beta	NOUN
fnp-3050	680	72	-	-	PUNCT
fnp-3050	680	73	peptide	peptide	NOUN
fnp-3050	680	74	pathology	pathology	NOUN
fnp-3050	680	75	and	and	CCONJ
fnp-3050	680	76	their	their	PRON
fnp-3050	680	77	relationship	relationship	NOUN
fnp-3050	680	78	to	to	PART
fnp-3050	680	79	amyloid	amyloid	VERB
fnp-3050	680	80	positron	positron	NOUN
fnp-3050	680	81	emission	emission	NOUN
fnp-3050	680	82	tomography	tomography	NOUN
fnp-3050	680	83	imaging	imaging	NOUN
fnp-3050	680	84	and	and	CCONJ
fnp-3050	680	85	dementia	dementia	NOUN
fnp-3050	680	86	.	.	PUNCT
fnp-3050	681	1	acta	acta	PROPN
fnp-3050	681	2	neuropathol	neuropathol	PROPN
fnp-3050	681	3	commun	commun	PROPN
fnp-3050	681	4	7:178	7:178	ADV
fnp-3050	681	5	82	82	NUM
fnp-3050	681	6	.	.	PUNCT
fnp-3050	682	1	mattsson	mattsson	PROPN
fnp-3050	682	2	n	n	CCONJ
fnp-3050	682	3	,	,	PUNCT
fnp-3050	682	4	palmqvist	palmqvist	NOUN
fnp-3050	682	5	s	s	PROPN
fnp-3050	682	6	,	,	PUNCT
fnp-3050	682	7	stomrud	stomrud	NOUN
fnp-3050	682	8	e	e	NOUN
fnp-3050	682	9	,	,	PUNCT
fnp-3050	682	10	vogel	vogel	PROPN
fnp-3050	682	11	j	j	PROPN
fnp-3050	682	12	,	,	PUNCT
fnp-3050	682	13	hansson	hansson	PROPN
fnp-3050	682	14	o	o	X
fnp-3050	682	15	(	(	PUNCT
fnp-3050	682	16	2019	2019	NUM
fnp-3050	682	17	)	)	PUNCT
fnp-3050	682	18	staging	stage	VERB
fnp-3050	682	19	beta	beta	NOUN
fnp-3050	682	20	-	-	PUNCT
fnp-3050	682	21	amyloid	amyloid	NOUN
fnp-3050	682	22	pathology	pathology	NOUN
fnp-3050	682	23	with	with	ADP
fnp-3050	682	24	amyloid	amyloid	NOUN
fnp-3050	682	25	positron	positron	NOUN
fnp-3050	682	26	emission	emission	NOUN
fnp-3050	682	27	tomography	tomography	NOUN
fnp-3050	682	28	.	.	PUNCT
fnp-3050	683	1	jama	jama	PROPN
fnp-3050	683	2	neurol	neurol	PROPN
fnp-3050	683	3	76:1319	76:1319	PROPN
fnp-3050	683	4	-	-	SYM
fnp-3050	683	5	1329	1329	NUM
fnp-3050	683	6	83	83	NUM
fnp-3050	683	7	.	.	PUNCT
fnp-3050	684	1	ikonomovic	ikonomovic	PROPN
fnp-3050	684	2	md	md	PROPN
fnp-3050	684	3	,	,	PUNCT
fnp-3050	684	4	buckley	buckley	PROPN
fnp-3050	684	5	cj	cj	PROPN
fnp-3050	684	6	,	,	PUNCT
fnp-3050	684	7	abrahamson	abrahamson	PROPN
fnp-3050	684	8	ee	ee	PROPN
fnp-3050	684	9	,	,	PUNCT
fnp-3050	684	10	kofler	kofler	PROPN
fnp-3050	684	11	jk	jk	PROPN
fnp-3050	684	12	,	,	PUNCT
fnp-3050	684	13	mathis	mathis	PROPN
fnp-3050	684	14	ca	ca	PROPN
fnp-3050	684	15	,	,	PUNCT
fnp-3050	684	16	klunk	klunk	VERB
fnp-3050	684	17	we	we	PRON
fnp-3050	684	18	,	,	PUNCT
fnp-3050	684	19	farrar	farrar	PROPN
fnp-3050	684	20	g	g	PROPN
fnp-3050	684	21	(	(	PUNCT
fnp-3050	684	22	2020	2020	NUM
fnp-3050	684	23	)	)	PUNCT
fnp-3050	684	24	post	post	ADJ
fnp-3050	684	25	-	-	ADJ
fnp-3050	684	26	mortem	mortem	ADJ
fnp-3050	684	27	analyses	analysis	NOUN
fnp-3050	684	28	of	of	ADP
fnp-3050	684	29	pib	pib	NOUN
fnp-3050	684	30	and	and	CCONJ
fnp-3050	684	31	flutemetamol	flutemetamol	VERB
fnp-3050	684	32	in	in	ADP
fnp-3050	684	33	diffuse	diffuse	NOUN
fnp-3050	684	34	and	and	CCONJ
fnp-3050	684	35	cored	core	VERB
fnp-3050	684	36	amyloid	amyloid	NOUN
fnp-3050	684	37	-	-	PUNCT
fnp-3050	684	38	beta	beta	NOUN
fnp-3050	684	39	plaques	plaque	NOUN
fnp-3050	684	40	in	in	ADP
fnp-3050	684	41	alzheimer	alzheimer	PROPN
fnp-3050	684	42	's	's	PART
fnp-3050	684	43	disease	disease	NOUN
fnp-3050	684	44	.	.	PUNCT
fnp-3050	685	1	acta	acta	PROPN
fnp-3050	685	2	neuropathol	neuropathol	PROPN
fnp-3050	685	3	140:463	140:463	NUM
fnp-3050	685	4	-	-	SYM
fnp-3050	685	5	476	476	NUM
fnp-3050	685	6	84	84	NUM
fnp-3050	685	7	.	.	PUNCT
fnp-3050	686	1	attems	attem	VERB
fnp-3050	686	2	j	j	PROPN
fnp-3050	686	3	(	(	PUNCT
fnp-3050	686	4	2005	2005	NUM
fnp-3050	686	5	)	)	PUNCT
fnp-3050	686	6	sporadic	sporadic	ADJ
fnp-3050	686	7	cerebral	cerebral	ADJ
fnp-3050	686	8	amyloid	amyloid	NOUN
fnp-3050	686	9	angiopathy	angiopathy	NOUN
fnp-3050	686	10	:	:	PUNCT
fnp-3050	686	11	pathology	pathology	NOUN
fnp-3050	686	12	,	,	PUNCT
fnp-3050	686	13	clinical	clinical	ADJ
fnp-3050	686	14	implications	implication	NOUN
fnp-3050	686	15	,	,	PUNCT
fnp-3050	686	16	and	and	CCONJ
fnp-3050	686	17	possible	possible	ADJ
fnp-3050	686	18	pathomechanisms	pathomechanism	NOUN
fnp-3050	686	19	.	.	PUNCT
fnp-3050	687	1	acta	acta	PROPN
fnp-3050	687	2	neuropathol	neuropathol	PROPN
fnp-3050	687	3	110:345	110:345	PROPN
fnp-3050	687	4	-	-	PUNCT
fnp-3050	687	5	359	359	NUM
fnp-3050	687	6	85	85	NUM
fnp-3050	687	7	.	.	PUNCT
fnp-3050	688	1	attems	attem	VERB
fnp-3050	688	2	j	j	PROPN
fnp-3050	688	3	,	,	PUNCT
fnp-3050	688	4	jellinger	jellinger	PROPN
fnp-3050	688	5	k	k	PROPN
fnp-3050	688	6	,	,	PUNCT
fnp-3050	688	7	thal	thal	PROPN
fnp-3050	688	8	dr	dr	PROPN
fnp-3050	688	9	,	,	PUNCT
fnp-3050	688	10	van	van	PROPN
fnp-3050	688	11	nostrand	nostrand	PROPN
fnp-3050	688	12	w	w	PROPN
fnp-3050	688	13	(	(	PUNCT
fnp-3050	688	14	2011	2011	NUM
fnp-3050	688	15	)	)	PUNCT
fnp-3050	688	16	review	review	NOUN
fnp-3050	688	17	:	:	PUNCT
fnp-3050	688	18	sporadic	sporadic	ADJ
fnp-3050	688	19	cerebral	cerebral	ADJ
fnp-3050	688	20	amyloid	amyloid	NOUN
fnp-3050	688	21	angiopathy	angiopathy	NOUN
fnp-3050	688	22	.	.	PUNCT
fnp-3050	689	1	neuropathol	neuropathol	PROPN
fnp-3050	689	2	appl	appl	PROPN
fnp-3050	689	3	neurobiol	neurobiol	PROPN
fnp-3050	689	4	37:75	37:75	NUM
fnp-3050	689	5	-	-	SYM
fnp-3050	689	6	93	93	NUM
fnp-3050	689	7	86	86	NUM
fnp-3050	689	8	.	.	PUNCT
fnp-3050	690	1	thal	thal	PROPN
fnp-3050	690	2	dr	dr	PROPN
fnp-3050	690	3	,	,	PUNCT
fnp-3050	690	4	griffin	griffin	PROPN
fnp-3050	690	5	ws	ws	PROPN
fnp-3050	690	6	,	,	PUNCT
fnp-3050	690	7	de	de	PROPN
fnp-3050	690	8	vos	vos	PROPN
fnp-3050	690	9	ra	ra	PROPN
fnp-3050	690	10	,	,	PUNCT
fnp-3050	690	11	ghebremedhin	ghebremedhin	NOUN
fnp-3050	690	12	e	e	PROPN
fnp-3050	690	13	(	(	PUNCT
fnp-3050	690	14	2008	2008	NUM
fnp-3050	690	15	)	)	PUNCT
fnp-3050	690	16	cerebral	cerebral	ADJ
fnp-3050	690	17	amyloid	amyloid	NOUN
fnp-3050	690	18	angiopathy	angiopathy	NOUN
fnp-3050	690	19	and	and	CCONJ
fnp-3050	690	20	its	its	PRON
fnp-3050	690	21	relationship	relationship	NOUN
fnp-3050	690	22	to	to	ADP
fnp-3050	690	23	alzheimer	alzheimer	PROPN
fnp-3050	690	24	's	's	PART
fnp-3050	690	25	disease	disease	NOUN
fnp-3050	690	26	.	.	PUNCT
fnp-3050	691	1	acta	acta	PROPN
fnp-3050	691	2	neuropathol	neuropathol	PROPN
fnp-3050	691	3	115:599	115:599	NUM
fnp-3050	691	4	-	-	PUNCT
fnp-3050	691	5	609	609	NUM
fnp-3050	691	6	87	87	NUM
fnp-3050	691	7	.	.	PUNCT
fnp-3050	692	1	allen	allen	PROPN
fnp-3050	692	2	n	n	PROPN
fnp-3050	692	3	,	,	PUNCT
fnp-3050	692	4	robinson	robinson	PROPN
fnp-3050	692	5	ac	ac	PROPN
fnp-3050	692	6	,	,	PUNCT
fnp-3050	692	7	snowden	snowden	PROPN
fnp-3050	692	8	j	j	PROPN
fnp-3050	692	9	,	,	PUNCT
fnp-3050	692	10	davidson	davidson	PROPN
fnp-3050	692	11	ys	ys	PROPN
fnp-3050	692	12	,	,	PUNCT
fnp-3050	692	13	mann	mann	PROPN
fnp-3050	692	14	dm	dm	PROPN
fnp-3050	692	15	(	(	PUNCT
fnp-3050	692	16	2014	2014	NUM
fnp-3050	692	17	)	)	PUNCT
fnp-3050	692	18	patterns	pattern	NOUN
fnp-3050	692	19	of	of	ADP
fnp-3050	692	20	cerebral	cerebral	ADJ
fnp-3050	692	21	amyloid	amyloid	NOUN
fnp-3050	692	22	angiopathy	angiopathy	NOUN
fnp-3050	692	23	define	define	VERB
fnp-3050	692	24	histopathological	histopathological	ADJ
fnp-3050	692	25	phenotypes	phenotype	NOUN
fnp-3050	692	26	in	in	ADP
fnp-3050	692	27	alzheimer	alzheimer	PROPN
fnp-3050	692	28	's	's	PART
fnp-3050	692	29	disease	disease	NOUN
fnp-3050	692	30	.	.	PUNCT
fnp-3050	693	1	neuropathol	neuropathol	PROPN
fnp-3050	693	2	appl	appl	PROPN
fnp-3050	693	3	neurobiol	neurobiol	PROPN
fnp-3050	693	4	40:136	40:136	PROPN
fnp-3050	693	5	-	-	SYM
fnp-3050	693	6	148	148	NUM
fnp-3050	693	7	88	88	NUM
fnp-3050	693	8	.	.	PUNCT
fnp-3050	694	1	love	love	PROPN
fnp-3050	694	2	s	s	PROPN
fnp-3050	694	3	,	,	PUNCT
fnp-3050	694	4	chalmers	chalmer	VERB
fnp-3050	694	5	k	k	PROPN
fnp-3050	694	6	,	,	PUNCT
fnp-3050	694	7	ince	ince	VERB
fnp-3050	694	8	p	p	X
fnp-3050	694	9	,	,	PUNCT
fnp-3050	694	10	esiri	esiri	PROPN
fnp-3050	694	11	m	m	PROPN
fnp-3050	694	12	,	,	PUNCT
fnp-3050	694	13	attems	attem	VERB
fnp-3050	694	14	j	j	PROPN
fnp-3050	694	15	,	,	PUNCT
fnp-3050	694	16	jellinger	jellinger	PROPN
fnp-3050	694	17	k	k	PROPN
fnp-3050	694	18	,	,	PUNCT
fnp-3050	694	19	yamada	yamada	PROPN
fnp-3050	694	20	m	m	PROPN
fnp-3050	694	21	,	,	PUNCT
fnp-3050	694	22	mccarron	mccarron	PROPN
fnp-3050	694	23	m	m	PROPN
fnp-3050	694	24	,	,	PUNCT
fnp-3050	694	25	minett	minett	PROPN
fnp-3050	694	26	t	t	PROPN
fnp-3050	694	27	,	,	PUNCT
fnp-3050	694	28	matthews	matthews	PROPN
fnp-3050	694	29	f	f	PROPN
fnp-3050	694	30	,	,	PUNCT
fnp-3050	694	31	greenberg	greenberg	PROPN
fnp-3050	694	32	s	s	PROPN
fnp-3050	694	33	,	,	PUNCT
fnp-3050	694	34	mann	mann	PROPN
fnp-3050	694	35	d	d	PROPN
fnp-3050	694	36	,	,	PUNCT
fnp-3050	694	37	kehoe	kehoe	PROPN
fnp-3050	694	38	pg	pg	PROPN
fnp-3050	694	39	(	(	PUNCT
fnp-3050	694	40	2014	2014	NUM
fnp-3050	694	41	)	)	PUNCT
fnp-3050	694	42	development	development	NOUN
fnp-3050	694	43	,	,	PUNCT
fnp-3050	694	44	appraisal	appraisal	NOUN
fnp-3050	694	45	,	,	PUNCT
fnp-3050	694	46	validation	validation	NOUN
fnp-3050	694	47	and	and	CCONJ
fnp-3050	694	48	implementation	implementation	NOUN
fnp-3050	694	49	of	of	ADP
fnp-3050	694	50	a	a	DET
fnp-3050	694	51	consensus	consensus	NOUN
fnp-3050	694	52	protocol	protocol	NOUN
fnp-3050	694	53	for	for	ADP
fnp-3050	694	54	the	the	DET
fnp-3050	694	55	assessment	assessment	NOUN
fnp-3050	694	56	of	of	ADP
fnp-3050	694	57	cerebral	cerebral	ADJ
fnp-3050	694	58	amyloid	amyloid	NOUN
fnp-3050	694	59	angiopathy	angiopathy	NOUN
fnp-3050	694	60	in	in	ADP
fnp-3050	694	61	post	post	ADJ
fnp-3050	694	62	-	-	ADJ
fnp-3050	694	63	mortem	mortem	ADJ
fnp-3050	694	64	brain	brain	NOUN
fnp-3050	694	65	tissue	tissue	NOUN
fnp-3050	694	66	.	.	PUNCT
fnp-3050	695	1	am	be	AUX
fnp-3050	695	2	j	j	PROPN
fnp-3050	695	3	neurodegener	neurodegener	NOUN
fnp-3050	695	4	dis	dis	PROPN
fnp-3050	695	5	3:19	3:19	NUM
fnp-3050	695	6	-	-	SYM
fnp-3050	695	7	32	32	NUM
fnp-3050	695	8	89	89	NUM
fnp-3050	695	9	.	.	PUNCT
fnp-3050	696	1	thal	thal	PROPN
fnp-3050	696	2	dr	dr	PROPN
fnp-3050	696	3	,	,	PUNCT
fnp-3050	696	4	ghebremedhin	ghebremedhin	NOUN
fnp-3050	696	5	e	e	NOUN
fnp-3050	696	6	,	,	PUNCT
fnp-3050	696	7	rub	rub	NOUN
fnp-3050	696	8	u	u	PROPN
fnp-3050	696	9	,	,	PUNCT
fnp-3050	696	10	yamaguchi	yamaguchi	PROPN
fnp-3050	696	11	h	h	PROPN
fnp-3050	696	12	,	,	PUNCT
fnp-3050	696	13	del	del	PROPN
fnp-3050	696	14	tredici	tredici	PROPN
fnp-3050	696	15	k	k	PROPN
fnp-3050	696	16	,	,	PUNCT
fnp-3050	696	17	braak	braak	PROPN
fnp-3050	696	18	h	h	PROPN
fnp-3050	696	19	(	(	PUNCT
fnp-3050	696	20	2002	2002	NUM
fnp-3050	696	21	)	)	PUNCT
fnp-3050	696	22	two	two	NUM
fnp-3050	696	23	types	type	NOUN
fnp-3050	696	24	of	of	ADP
fnp-3050	696	25	sporadic	sporadic	ADJ
fnp-3050	696	26	cerebral	cerebral	ADJ
fnp-3050	696	27	amyloid	amyloid	NOUN
fnp-3050	696	28	angiopathy	angiopathy	NOUN
fnp-3050	696	29	.	.	PUNCT
fnp-3050	697	1	j	j	PROPN
fnp-3050	697	2	neuropathol	neuropathol	PROPN
fnp-3050	697	3	exp	exp	PROPN
fnp-3050	697	4	neurol	neurol	PROPN
fnp-3050	697	5	61:282	61:282	NUM
fnp-3050	697	6	-	-	SYM
fnp-3050	697	7	293	293	NUM
fnp-3050	697	8	90	90	NUM
fnp-3050	697	9	.	.	PUNCT
fnp-3050	698	1	nortley	nortley	PROPN
fnp-3050	698	2	r	r	PROPN
fnp-3050	698	3	,	,	PUNCT
fnp-3050	698	4	korte	korte	PROPN
fnp-3050	698	5	n	n	CCONJ
fnp-3050	698	6	,	,	PUNCT
fnp-3050	698	7	izquierdo	izquierdo	PROPN
fnp-3050	698	8	p	p	NOUN
fnp-3050	698	9	,	,	PUNCT
fnp-3050	698	10	hirunpattarasilp	hirunpattarasilp	ADJ
fnp-3050	698	11	c	c	PROPN
fnp-3050	698	12	,	,	PUNCT
fnp-3050	698	13	mishra	mishra	PROPN
fnp-3050	698	14	a	a	PROPN
fnp-3050	698	15	,	,	PUNCT
fnp-3050	698	16	jaunmuktane	jaunmuktane	NOUN
fnp-3050	698	17	z	z	PROPN
fnp-3050	698	18	,	,	PUNCT
fnp-3050	698	19	kyrargyri	kyrargyri	VERB
fnp-3050	698	20	v	v	PROPN
fnp-3050	698	21	,	,	PUNCT
fnp-3050	698	22	pfeiffer	pfeiffer	PROPN
fnp-3050	698	23	t	t	PROPN
fnp-3050	698	24	,	,	PUNCT
fnp-3050	698	25	khennouf	khennouf	PROPN
fnp-3050	698	26	l	l	NOUN
fnp-3050	698	27	,	,	PUNCT
fnp-3050	698	28	madry	madry	PROPN
fnp-3050	698	29	c	c	AUX
fnp-3050	698	30	,	,	PUNCT
fnp-3050	698	31	gong	gong	PROPN
fnp-3050	698	32	h	h	PROPN
fnp-3050	698	33	,	,	PUNCT
fnp-3050	698	34	richard	richard	NOUN
fnp-3050	698	35	-	-	PUNCT
fnp-3050	698	36	loendt	loendt	PROPN
fnp-3050	698	37	a	a	NOUN
fnp-3050	698	38	,	,	PUNCT
fnp-3050	698	39	huang	huang	PROPN
fnp-3050	698	40	w	w	PROPN
fnp-3050	698	41	,	,	PUNCT
fnp-3050	698	42	saito	saito	PROPN
fnp-3050	698	43	t	t	PROPN
fnp-3050	698	44	,	,	PUNCT
fnp-3050	698	45	saido	saido	PROPN
fnp-3050	698	46	tc	tc	PROPN
fnp-3050	698	47	,	,	PUNCT
fnp-3050	698	48	brandner	brandner	NOUN
fnp-3050	698	49	s	s	PROPN
fnp-3050	698	50	,	,	PUNCT
fnp-3050	698	51	sethi	sethi	PROPN
fnp-3050	698	52	h	h	PROPN
fnp-3050	698	53	,	,	PUNCT
fnp-3050	698	54	attwell	attwell	ADJ
fnp-3050	698	55	d	d	X
fnp-3050	698	56	(	(	PUNCT
fnp-3050	698	57	2019	2019	NUM
fnp-3050	698	58	)	)	PUNCT
fnp-3050	698	59	amyloid	amyloid	NOUN
fnp-3050	698	60	beta	beta	ADJ
fnp-3050	698	61	oligomers	oligomer	NOUN
fnp-3050	698	62	constrict	constrict	VERB
fnp-3050	698	63	human	human	ADJ
fnp-3050	698	64	capillaries	capillary	NOUN
fnp-3050	698	65	in	in	ADP
fnp-3050	698	66	alzheimer	alzheimer	PROPN
fnp-3050	698	67	's	's	PART
fnp-3050	698	68	disease	disease	NOUN
fnp-3050	698	69	via	via	ADP
fnp-3050	698	70	signaling	signal	VERB
fnp-3050	698	71	to	to	ADP
fnp-3050	698	72	pericytes	pericyte	NOUN
fnp-3050	698	73	.	.	PUNCT
fnp-3050	699	1	science	science	NOUN
fnp-3050	699	2	365	365	NUM
fnp-3050	699	3	:	:	PUNCT
fnp-3050	699	4	eaav9518	eaav9518	PROPN
fnp-3050	699	5	doi	doi	NOUN
fnp-3050	699	6	9510.1126	9510.1126	PROPN
fnp-3050	699	7	/	/	SYM
fnp-3050	699	8	science.aav9518	science.aav9518	NUM
fnp-3050	699	9	91	91	NUM
fnp-3050	699	10	.	.	PUNCT
fnp-3050	700	1	attems	attems	PROPN
fnp-3050	700	2	j	j	PROPN
fnp-3050	700	3	,	,	PUNCT
fnp-3050	700	4	jellinger	jellinger	PROPN
fnp-3050	700	5	ka	ka	PROPN
fnp-3050	700	6	(	(	PUNCT
fnp-3050	700	7	2014	2014	NUM
fnp-3050	700	8	)	)	PUNCT
fnp-3050	700	9	pathologic	pathologic	ADJ
fnp-3050	700	10	aspects	aspect	NOUN
fnp-3050	700	11	of	of	ADP
fnp-3050	700	12	the	the	DET
fnp-3050	700	13	hemorrhagic	hemorrhagic	NOUN
fnp-3050	700	14	consequences	consequence	NOUN
fnp-3050	700	15	of	of	ADP
fnp-3050	700	16	small	small	ADJ
fnp-3050	700	17	vessel	vessel	NOUN
fnp-3050	700	18	disease	disease	NOUN
fnp-3050	700	19	on	on	ADP
fnp-3050	700	20	the	the	DET
fnp-3050	700	21	brain	brain	NOUN
fnp-3050	700	22	.	.	PUNCT
fnp-3050	701	1	in	in	ADP
fnp-3050	701	2	:	:	PUNCT
fnp-3050	701	3	pantoni	pantoni	ADJ
fnp-3050	701	4	l	l	NOUN
fnp-3050	701	5	,	,	PUNCT
fnp-3050	701	6	gorelick	gorelick	NOUN
fnp-3050	701	7	pb	pb	ADP
fnp-3050	701	8	(	(	PUNCT
fnp-3050	701	9	eds	ed	NOUN
fnp-3050	701	10	)	)	PUNCT
fnp-3050	701	11	cerebral	cerebral	ADJ
fnp-3050	701	12	small	small	ADJ
fnp-3050	701	13	vessel	vessel	NOUN
fnp-3050	701	14	disease	disease	NOUN
fnp-3050	701	15	.	.	PUNCT
fnp-3050	702	1	cambridge	cambridge	PROPN
fnp-3050	702	2	university	university	PROPN
fnp-3050	702	3	press	press	PROPN
fnp-3050	702	4	cambridge	cambridge	PROPN
fnp-3050	702	5	,	,	PUNCT
fnp-3050	702	6	uk	uk	PROPN
fnp-3050	702	7	,	,	PUNCT
fnp-3050	702	8	pp	pp	ADV
fnp-3050	702	9	29	29	NUM
fnp-3050	702	10	-	-	SYM
fnp-3050	702	11	41	41	NUM
fnp-3050	702	12	92	92	NUM
fnp-3050	702	13	.	.	PUNCT
fnp-3050	703	1	planton	planton	PROPN
fnp-3050	703	2	m	m	PROPN
fnp-3050	703	3	,	,	PUNCT
fnp-3050	703	4	pariente	pariente	PROPN
fnp-3050	703	5	j	j	PROPN
fnp-3050	703	6	,	,	PUNCT
fnp-3050	703	7	nemmi	nemmi	VERB
fnp-3050	703	8	f	f	NOUN
fnp-3050	703	9	,	,	PUNCT
fnp-3050	703	10	albucher	albucher	PROPN
fnp-3050	703	11	jf	jf	PROPN
fnp-3050	703	12	,	,	PUNCT
fnp-3050	703	13	calviere	calviere	ADP
fnp-3050	703	14	l	l	NOUN
fnp-3050	703	15	,	,	PUNCT
fnp-3050	703	16	viguier	viguier	AUX
fnp-3050	703	17	a	a	PRON
fnp-3050	703	18	,	,	PUNCT
fnp-3050	703	19	olivot	olivot	PROPN
fnp-3050	703	20	jm	jm	PROPN
fnp-3050	703	21	,	,	PUNCT
fnp-3050	703	22	salabert	salabert	VERB
fnp-3050	703	23	as	as	ADP
fnp-3050	703	24	,	,	PUNCT
fnp-3050	703	25	payoux	payoux	VERB
fnp-3050	703	26	p	p	NOUN
fnp-3050	703	27	,	,	PUNCT
fnp-3050	703	28	peran	peran	NOUN
fnp-3050	703	29	p	p	PRON
fnp-3050	703	30	,	,	PUNCT
fnp-3050	703	31	raposo	raposo	VERB
fnp-3050	703	32	n	n	PROPN
fnp-3050	703	33	(	(	PUNCT
fnp-3050	703	34	2020	2020	NUM
fnp-3050	703	35	)	)	PUNCT
fnp-3050	703	36	interhemispheric	interhemispheric	ADJ
fnp-3050	703	37	distribution	distribution	NOUN
fnp-3050	703	38	of	of	ADP
fnp-3050	703	39	amyloid	amyloid	NOUN
fnp-3050	703	40	and	and	CCONJ
fnp-3050	703	41	small	small	ADJ
fnp-3050	703	42	vessel	vessel	NOUN
fnp-3050	703	43	disease	disease	NOUN
fnp-3050	703	44	burden	burden	NOUN
fnp-3050	703	45	in	in	ADP
fnp-3050	703	46	cerebral	cerebral	ADJ
fnp-3050	703	47	amyloid	amyloid	NOUN
fnp-3050	703	48	angiopathy	angiopathy	ADJ
fnp-3050	703	49	-	-	PUNCT
fnp-3050	703	50	related	relate	VERB
fnp-3050	703	51	intracerebral	intracerebral	ADJ
fnp-3050	703	52	hemorrhage	hemorrhage	NOUN
fnp-3050	703	53	.	.	PUNCT
fnp-3050	704	1	eur	eur	PROPN
fnp-3050	704	2	j	j	PROPN
fnp-3050	704	3	neurol	neurol	PROPN
fnp-3050	704	4	27:1664	27:1664	PROPN
fnp-3050	704	5	-	-	PROPN
fnp-3050	704	6	1671	1671	NUM
fnp-3050	704	7	93	93	NUM
fnp-3050	704	8	.	.	PUNCT
fnp-3050	705	1	schreiber	schreiber	PROPN
fnp-3050	705	2	s	s	PART
fnp-3050	705	3	,	,	PUNCT
fnp-3050	705	4	wilisch	wilisch	ADV
fnp-3050	705	5	-	-	PUNCT
fnp-3050	705	6	neumann	neumann	PROPN
fnp-3050	705	7	a	a	PROPN
fnp-3050	705	8	,	,	PUNCT
fnp-3050	705	9	schreiber	schreiber	PROPN
fnp-3050	705	10	f	f	PROPN
fnp-3050	705	11	,	,	PUNCT
fnp-3050	705	12	assmann	assmann	PROPN
fnp-3050	705	13	a	a	PROPN
fnp-3050	705	14	,	,	PUNCT
fnp-3050	705	15	scheumann	scheumann	PROPN
fnp-3050	705	16	v	v	NOUN
fnp-3050	705	17	,	,	PUNCT
fnp-3050	705	18	perosa	perosa	NOUN
fnp-3050	705	19	v	v	NOUN
fnp-3050	705	20	,	,	PUNCT
fnp-3050	705	21	jandke	jandke	NOUN
fnp-3050	705	22	s	s	PART
fnp-3050	705	23	,	,	PUNCT
fnp-3050	705	24	mawrin	mawrin	NOUN
fnp-3050	705	25	c	c	PROPN
fnp-3050	705	26	,	,	PUNCT
fnp-3050	705	27	carare	carare	PROPN
fnp-3050	705	28	ro	ro	NOUN
fnp-3050	705	29	,	,	PUNCT
fnp-3050	705	30	werring	werring	NOUN
fnp-3050	705	31	dj	dj	NOUN
fnp-3050	705	32	(	(	PUNCT
fnp-3050	705	33	2020	2020	NUM
fnp-3050	705	34	)	)	PUNCT
fnp-3050	705	35	the	the	DET
fnp-3050	705	36	spectrum	spectrum	NOUN
fnp-3050	705	37	of	of	ADP
fnp-3050	705	38	age	age	NOUN
fnp-3050	705	39	-	-	PUNCT
fnp-3050	705	40	related	relate	VERB
fnp-3050	705	41	small	small	ADJ
fnp-3050	705	42	vessel	vessel	NOUN
fnp-3050	705	43	diseases	disease	NOUN
fnp-3050	705	44	:	:	PUNCT
fnp-3050	705	45	potential	potential	ADJ
fnp-3050	705	46	overlap	overlap	NOUN
fnp-3050	705	47	and	and	CCONJ
fnp-3050	705	48	interactions	interaction	NOUN
fnp-3050	705	49	of	of	ADP
fnp-3050	705	50	amyloid	amyloid	NOUN
fnp-3050	705	51	and	and	CCONJ
fnp-3050	705	52	nonamyloid	nonamyloid	NOUN
fnp-3050	705	53	vasculopathies	vasculopathie	NOUN
fnp-3050	705	54	.	.	PUNCT
fnp-3050	706	1	neuropathol	neuropathol	NOUN
fnp-3050	706	2	appl	appl	PROPN
fnp-3050	706	3	neurobiol	neurobiol	PROPN
fnp-3050	706	4	46:219	46:219	PROPN
fnp-3050	706	5	-	-	SYM
fnp-3050	706	6	239	239	NUM
fnp-3050	706	7	94	94	NUM
fnp-3050	706	8	.	.	PUNCT
fnp-3050	707	1	lafon	lafon	PROPN
fnp-3050	708	1	pa	pa	PROPN
fnp-3050	708	2	,	,	PUNCT
fnp-3050	708	3	wang	wang	PROPN
fnp-3050	708	4	y	y	PROPN
fnp-3050	708	5	,	,	PUNCT
fnp-3050	708	6	arango	arango	PROPN
fnp-3050	708	7	-	-	PUNCT
fnp-3050	708	8	lievano	lievano	PROPN
fnp-3050	708	9	m	m	PROPN
fnp-3050	708	10	,	,	PUNCT
fnp-3050	708	11	torrent	torrent	PROPN
fnp-3050	708	12	j	j	PROPN
fnp-3050	708	13	,	,	PUNCT
fnp-3050	708	14	salvador	salvador	NOUN
fnp-3050	708	15	-	-	PUNCT
fnp-3050	708	16	prince	prince	PROPN
fnp-3050	708	17	l	l	PROPN
fnp-3050	708	18	,	,	PUNCT
fnp-3050	708	19	mansuy	mansuy	PROPN
fnp-3050	708	20	m	m	PROPN
fnp-3050	708	21	,	,	PUNCT
fnp-3050	708	22	mestre	mestre	NOUN
fnp-3050	708	23	-	-	PUNCT
fnp-3050	708	24	francès	francès	NOUN
fnp-3050	708	25	n	n	CCONJ
fnp-3050	708	26	,	,	PUNCT
fnp-3050	708	27	givalois	givalois	PROPN
fnp-3050	708	28	l	l	PROPN
fnp-3050	708	29	,	,	PUNCT
fnp-3050	708	30	liu	liu	PROPN
fnp-3050	708	31	j	j	PROPN
fnp-3050	708	32	,	,	PUNCT
fnp-3050	708	33	mercader	mercader	PROPN
fnp-3050	708	34	jv	jv	PROPN
fnp-3050	708	35	,	,	PUNCT
fnp-3050	708	36	jeanneteau	jeanneteau	PROPN
fnp-3050	708	37	f	f	X
fnp-3050	708	38	,	,	PUNCT
fnp-3050	708	39	desrumaux	desrumaux	PROPN
fnp-3050	708	40	c	c	NOUN
fnp-3050	708	41	,	,	PUNCT
fnp-3050	708	42	perrier	perrier	NOUN
fnp-3050	708	43	v	v	NOUN
fnp-3050	708	44	(	(	PUNCT
fnp-3050	708	45	2020	2020	NUM
fnp-3050	708	46	)	)	PUNCT
fnp-3050	708	47	fungicide	fungicide	NOUN
fnp-3050	708	48	residues	residue	VERB
fnp-3050	708	49	exposure	exposure	NOUN
fnp-3050	708	50	and	and	CCONJ
fnp-3050	708	51	beta	beta	NOUN
fnp-3050	708	52	-	-	PUNCT
fnp-3050	708	53	amyloid	amyloid	NOUN
fnp-3050	708	54	aggregation	aggregation	NOUN
fnp-3050	708	55	in	in	ADP
fnp-3050	708	56	a	a	DET
fnp-3050	708	57	mouse	mouse	NOUN
fnp-3050	708	58	model	model	NOUN
fnp-3050	708	59	of	of	ADP
fnp-3050	708	60	alzheimer	alzheimer	PROPN
fnp-3050	708	61	's	's	PART
fnp-3050	708	62	disease	disease	NOUN
fnp-3050	708	63	.	.	PUNCT
fnp-3050	709	1	environ	environ	PROPN
fnp-3050	709	2	health	health	NOUN
fnp-3050	709	3	perspect	perspect	NOUN
fnp-3050	709	4	128:17011	128:17011	NUM
fnp-3050	709	5	95	95	NUM
fnp-3050	709	6	.	.	PUNCT
fnp-3050	710	1	gatti	gatti	PROPN
fnp-3050	710	2	l	l	PROPN
fnp-3050	710	3	,	,	PUNCT
fnp-3050	710	4	tinelli	tinelli	NOUN
fnp-3050	710	5	f	f	NUM
fnp-3050	710	6	,	,	PUNCT
fnp-3050	710	7	scelzo	scelzo	VERB
fnp-3050	710	8	e	e	NOUN
fnp-3050	710	9	,	,	PUNCT
fnp-3050	710	10	arioli	arioli	PROPN
fnp-3050	710	11	f	f	PROPN
fnp-3050	710	12	,	,	PUNCT
fnp-3050	710	13	di	di	X
fnp-3050	710	14	fede	fede	PROPN
fnp-3050	710	15	g	g	PROPN
fnp-3050	710	16	,	,	PUNCT
fnp-3050	710	17	obici	obici	PROPN
fnp-3050	710	18	l	l	NOUN
fnp-3050	710	19	,	,	PUNCT
fnp-3050	710	20	pantoni	pantoni	ADJ
fnp-3050	710	21	l	l	NOUN
fnp-3050	710	22	,	,	PUNCT
fnp-3050	710	23	giaccone	giaccone	PROPN
fnp-3050	710	24	g	g	PROPN
fnp-3050	710	25	,	,	PUNCT
fnp-3050	710	26	caroppo	caroppo	ADJ
fnp-3050	710	27	p	p	X
fnp-3050	710	28	,	,	PUNCT
fnp-3050	710	29	parati	parati	NOUN
fnp-3050	710	30	ea	ea	PROPN
fnp-3050	710	31	,	,	PUNCT
fnp-3050	710	32	bersano	bersano	VERB
fnp-3050	710	33	a	a	DET
fnp-3050	710	34	(	(	PUNCT
fnp-3050	710	35	2020	2020	NUM
fnp-3050	710	36	)	)	PUNCT
fnp-3050	710	37	understanding	understand	VERB
fnp-3050	710	38	the	the	DET
fnp-3050	710	39	pathophysiology	pathophysiology	NOUN
fnp-3050	710	40	of	of	ADP
fnp-3050	710	41	cerebral	cerebral	ADJ
fnp-3050	710	42	amyloid	amyloid	NOUN
fnp-3050	710	43	angiopathy	angiopathy	NOUN
fnp-3050	710	44	.	.	PUNCT
fnp-3050	711	1	int	int	PROPN
fnp-3050	711	2	j	j	PROPN
fnp-3050	711	3	mol	mol	ADP
fnp-3050	711	4	sci	sci	PROPN
fnp-3050	711	5	21	21	NUM
fnp-3050	711	6	96	96	NUM
fnp-3050	711	7	.	.	PUNCT
fnp-3050	712	1	greenberg	greenberg	PROPN
fnp-3050	712	2	sm	sm	PROPN
fnp-3050	712	3	,	,	PUNCT
fnp-3050	712	4	bacskai	bacskai	NOUN
fnp-3050	712	5	bj	bj	NOUN
fnp-3050	712	6	,	,	PUNCT
fnp-3050	712	7	hernandez	hernandez	PROPN
fnp-3050	712	8	-	-	PUNCT
fnp-3050	712	9	guillamon	guillamon	PROPN
fnp-3050	712	10	m	m	PROPN
fnp-3050	712	11	,	,	PUNCT
fnp-3050	712	12	pruzin	pruzin	PROPN
fnp-3050	712	13	j	j	PROPN
fnp-3050	712	14	,	,	PUNCT
fnp-3050	712	15	sperling	sperling	PROPN
fnp-3050	712	16	r	r	PROPN
fnp-3050	712	17	,	,	PUNCT
fnp-3050	712	18	van	van	PROPN
fnp-3050	712	19	veluw	veluw	NOUN
fnp-3050	712	20	sj	sj	INTJ
fnp-3050	712	21	(	(	PUNCT
fnp-3050	712	22	2020	2020	NUM
fnp-3050	712	23	)	)	PUNCT
fnp-3050	712	24	cerebral	cerebral	ADJ
fnp-3050	712	25	amyloid	amyloid	NOUN
fnp-3050	712	26	angiopathy	angiopathy	ADJ
fnp-3050	712	27	and	and	CCONJ
fnp-3050	712	28	alzheimer	alzheimer	NOUN
fnp-3050	712	29	disease	disease	NOUN
fnp-3050	712	30	one	one	NUM
fnp-3050	712	31	peptide	peptide	NOUN
fnp-3050	712	32	,	,	PUNCT
fnp-3050	712	33	two	two	NUM
fnp-3050	712	34	pathways	pathway	NOUN
fnp-3050	712	35	.	.	PUNCT
fnp-3050	713	1	nat	nat	PROPN
fnp-3050	713	2	rev	rev	VERB
fnp-3050	713	3	neurol	neurol	PROPN
fnp-3050	713	4	16:30	16:30	NUM
fnp-3050	713	5	-	-	SYM
fnp-3050	713	6	42	42	NUM
fnp-3050	713	7	97	97	NUM
fnp-3050	713	8	.	.	PUNCT
fnp-3050	714	1	revesz	revesz	PROPN
fnp-3050	714	2	t	t	PROPN
fnp-3050	714	3	,	,	PUNCT
fnp-3050	714	4	ghiso	ghiso	PROPN
fnp-3050	714	5	j	j	PROPN
fnp-3050	714	6	,	,	PUNCT
fnp-3050	714	7	lashley	lashley	PROPN
fnp-3050	714	8	t	t	PROPN
fnp-3050	714	9	,	,	PUNCT
fnp-3050	714	10	plant	plant	NOUN
fnp-3050	714	11	g	g	NOUN
fnp-3050	714	12	,	,	PUNCT
fnp-3050	714	13	rostagno	rostagno	NOUN
fnp-3050	714	14	a	a	NOUN
fnp-3050	714	15	,	,	PUNCT
fnp-3050	714	16	frangione	frangione	NOUN
fnp-3050	714	17	b	b	PROPN
fnp-3050	714	18	,	,	PUNCT
fnp-3050	714	19	holton	holton	PROPN
fnp-3050	714	20	jl	jl	PROPN
fnp-3050	714	21	(	(	PUNCT
fnp-3050	714	22	2003	2003	NUM
fnp-3050	714	23	)	)	PUNCT
fnp-3050	714	24	cerebral	cerebral	ADJ
fnp-3050	714	25	amyloid	amyloid	NOUN
fnp-3050	714	26	angiopathies	angiopathy	NOUN
fnp-3050	714	27	:	:	PUNCT
fnp-3050	714	28	a	a	DET
fnp-3050	714	29	pathologic	pathologic	ADJ
fnp-3050	714	30	,	,	PUNCT
fnp-3050	714	31	biochemical	biochemical	ADJ
fnp-3050	714	32	,	,	PUNCT
fnp-3050	714	33	and	and	CCONJ
fnp-3050	714	34	genetic	genetic	ADJ
fnp-3050	714	35	view	view	NOUN
fnp-3050	714	36	.	.	PUNCT
fnp-3050	715	1	j	j	PROPN
fnp-3050	715	2	neuropathol	neuropathol	PROPN
fnp-3050	715	3	exp	exp	PROPN
fnp-3050	715	4	neurol	neurol	PROPN
fnp-3050	715	5	62:885	62:885	NUM
fnp-3050	715	6	-	-	SYM
fnp-3050	715	7	898	898	NUM
fnp-3050	715	8	98	98	NUM
fnp-3050	715	9	.	.	PUNCT
fnp-3050	716	1	neve	neve	PROPN
fnp-3050	716	2	rl	rl	PROPN
fnp-3050	716	3	,	,	PUNCT
fnp-3050	716	4	harris	harris	PROPN
fnp-3050	716	5	p	p	PROPN
fnp-3050	716	6	,	,	PUNCT
fnp-3050	716	7	kosik	kosik	PROPN
fnp-3050	716	8	ks	ks	PROPN
fnp-3050	716	9	,	,	PUNCT
fnp-3050	716	10	kurnit	kurnit	PROPN
fnp-3050	716	11	dm	dm	PROPN
fnp-3050	716	12	,	,	PUNCT
fnp-3050	716	13	donlon	donlon	NOUN
fnp-3050	716	14	ta	ta	PROPN
fnp-3050	716	15	(	(	PUNCT
fnp-3050	716	16	1986	1986	NUM
fnp-3050	716	17	)	)	PUNCT
fnp-3050	716	18	identification	identification	NOUN
fnp-3050	716	19	of	of	ADP
fnp-3050	716	20	cdna	cdna	PROPN
fnp-3050	716	21	clones	clone	NOUN
fnp-3050	716	22	for	for	ADP
fnp-3050	716	23	the	the	DET
fnp-3050	716	24	human	human	ADJ
fnp-3050	716	25	microtubule	microtubule	NOUN
fnp-3050	716	26	-	-	PUNCT
fnp-3050	716	27	associated	associate	VERB
fnp-3050	716	28	protein	protein	NOUN
fnp-3050	716	29	tau	tau	NOUN
fnp-3050	716	30	and	and	CCONJ
fnp-3050	716	31	chromosomal	chromosomal	ADJ
fnp-3050	716	32	localization	localization	NOUN
fnp-3050	716	33	of	of	ADP
fnp-3050	716	34	the	the	DET
fnp-3050	716	35	genes	gene	NOUN
fnp-3050	716	36	for	for	ADP
fnp-3050	716	37	tau	tau	PROPN
fnp-3050	716	38	and	and	CCONJ
fnp-3050	716	39	microtubule	microtubule	NOUN
fnp-3050	716	40	-	-	PUNCT
fnp-3050	716	41	associated	associate	VERB
fnp-3050	716	42	protein	protein	NOUN
fnp-3050	716	43	2	2	NUM
fnp-3050	716	44	.	.	PUNCT
fnp-3050	716	45	brain	brain	NOUN
fnp-3050	716	46	res	re	NOUN
fnp-3050	716	47	387:271	387:271	NOUN
fnp-3050	716	48	-	-	PUNCT
fnp-3050	716	49	280	280	NUM
fnp-3050	716	50	99	99	NUM
fnp-3050	716	51	.	.	PUNCT
fnp-3050	717	1	guo	guo	PROPN
fnp-3050	717	2	t	t	PROPN
fnp-3050	717	3	,	,	PUNCT
fnp-3050	717	4	noble	noble	ADJ
fnp-3050	717	5	w	w	NOUN
fnp-3050	717	6	,	,	PUNCT
fnp-3050	717	7	hanger	hanger	NOUN
fnp-3050	717	8	dp	dp	NOUN
fnp-3050	717	9	(	(	PUNCT
fnp-3050	717	10	2017	2017	NUM
fnp-3050	717	11	)	)	PUNCT
fnp-3050	717	12	roles	role	NOUN
fnp-3050	717	13	of	of	ADP
fnp-3050	717	14	tau	tau	PROPN
fnp-3050	717	15	protein	protein	NOUN
fnp-3050	717	16	in	in	ADP
fnp-3050	717	17	health	health	NOUN
fnp-3050	717	18	and	and	CCONJ
fnp-3050	717	19	disease	disease	NOUN
fnp-3050	717	20	.	.	PUNCT
fnp-3050	718	1	acta	acta	PROPN
fnp-3050	718	2	neuropathol	neuropathol	PROPN
fnp-3050	718	3	133:665	133:665	NOUN
fnp-3050	718	4	-	-	PUNCT
fnp-3050	718	5	704	704	NUM
fnp-3050	718	6	100	100	NUM
fnp-3050	718	7	.	.	PUNCT
fnp-3050	719	1	holmes	holmes	PROPN
fnp-3050	719	2	bb	bb	PROPN
fnp-3050	719	3	,	,	PUNCT
fnp-3050	719	4	diamond	diamond	PROPN
fnp-3050	719	5	mi	mi	PROPN
fnp-3050	719	6	(	(	PUNCT
fnp-3050	719	7	2014	2014	NUM
fnp-3050	719	8	)	)	PUNCT
fnp-3050	719	9	prion	prion	NOUN
fnp-3050	719	10	-	-	PUNCT
fnp-3050	719	11	like	like	ADJ
fnp-3050	719	12	properties	property	NOUN
fnp-3050	719	13	of	of	ADP
fnp-3050	719	14	tau	tau	PROPN
fnp-3050	719	15	protein	protein	NOUN
fnp-3050	719	16	:	:	PUNCT
fnp-3050	719	17	the	the	DET
fnp-3050	719	18	importance	importance	NOUN
fnp-3050	719	19	of	of	ADP
fnp-3050	719	20	extracellular	extracellular	ADJ
fnp-3050	719	21	tau	tau	PROPN
fnp-3050	719	22	as	as	ADP
fnp-3050	719	23	a	a	DET
fnp-3050	719	24	therapeutic	therapeutic	ADJ
fnp-3050	719	25	target	target	NOUN
fnp-3050	719	26	.	.	PUNCT
fnp-3050	720	1	j	j	PROPN
fnp-3050	720	2	biol	biol	PROPN
fnp-3050	720	3	chem	chem	NOUN
fnp-3050	720	4	289:19855	289:19855	PROPN
fnp-3050	720	5	-	-	SYM
fnp-3050	720	6	19861	19861	NUM
fnp-3050	720	7	101	101	NUM
fnp-3050	720	8	.	.	PUNCT
fnp-3050	721	1	kfoury	kfoury	PROPN
fnp-3050	721	2	n	n	CCONJ
fnp-3050	721	3	,	,	PUNCT
fnp-3050	721	4	holmes	holmes	PROPN
fnp-3050	721	5	bb	bb	PROPN
fnp-3050	721	6	,	,	PUNCT
fnp-3050	721	7	jiang	jiang	PROPN
fnp-3050	721	8	h	h	PROPN
fnp-3050	721	9	,	,	PUNCT
fnp-3050	721	10	holtzman	holtzman	ADJ
fnp-3050	721	11	dm	dm	PROPN
fnp-3050	721	12	,	,	PUNCT
fnp-3050	721	13	diamond	diamond	NOUN
fnp-3050	721	14	mi	mi	PROPN
fnp-3050	721	15	(	(	PUNCT
fnp-3050	721	16	2012	2012	NUM
fnp-3050	721	17	)	)	PUNCT
fnp-3050	721	18	trans	trans	ADJ
fnp-3050	721	19	-	-	ADJ
fnp-3050	721	20	cellular	cellular	ADJ
fnp-3050	721	21	propagation	propagation	NOUN
fnp-3050	721	22	of	of	ADP
fnp-3050	721	23	tau	tau	PROPN
fnp-3050	721	24	aggregation	aggregation	NOUN
fnp-3050	721	25	by	by	ADP
fnp-3050	721	26	fibrillar	fibrillar	ADJ
fnp-3050	721	27	species	specie	NOUN
fnp-3050	721	28	.	.	PUNCT
fnp-3050	722	1	j	j	PROPN
fnp-3050	722	2	biol	biol	PROPN
fnp-3050	722	3	chem	chem	NOUN
fnp-3050	722	4	287:19440	287:19440	NUM
fnp-3050	722	5	-	-	SYM
fnp-3050	722	6	19451	19451	NUM
fnp-3050	722	7	102	102	NUM
fnp-3050	722	8	.	.	PUNCT
fnp-3050	723	1	de	de	X
fnp-3050	723	2	calignon	calignon	PROPN
fnp-3050	723	3	a	a	PROPN
fnp-3050	723	4	,	,	PUNCT
fnp-3050	723	5	fox	fox	PROPN
fnp-3050	723	6	lm	lm	PROPN
fnp-3050	723	7	,	,	PUNCT
fnp-3050	723	8	pitstick	pitstick	NOUN
fnp-3050	723	9	r	r	NOUN
fnp-3050	723	10	,	,	PUNCT
fnp-3050	723	11	carlson	carlson	PROPN
fnp-3050	723	12	ga	ga	PROPN
fnp-3050	723	13	,	,	PUNCT
fnp-3050	723	14	bacskai	bacskai	ADJ
fnp-3050	723	15	bj	bj	NOUN
fnp-3050	723	16	,	,	PUNCT
fnp-3050	723	17	spires	spire	NOUN
fnp-3050	723	18	-	-	PUNCT
fnp-3050	723	19	jones	jones	PROPN
fnp-3050	723	20	tl	tl	PROPN
fnp-3050	723	21	,	,	PUNCT
fnp-3050	723	22	hyman	hyman	PROPN
fnp-3050	723	23	bt	bt	PROPN
fnp-3050	723	24	(	(	PUNCT
fnp-3050	723	25	2010	2010	NUM
fnp-3050	723	26	)	)	PUNCT
fnp-3050	723	27	caspase	caspase	NOUN
fnp-3050	723	28	activation	activation	NOUN
fnp-3050	723	29	precedes	precede	VERB
fnp-3050	723	30	and	and	CCONJ
fnp-3050	723	31	leads	lead	VERB
fnp-3050	723	32	to	to	ADP
fnp-3050	723	33	tangles	tangle	NOUN
fnp-3050	723	34	.	.	PUNCT
fnp-3050	724	1	nature	nature	NOUN
fnp-3050	724	2	464:1201	464:1201	NUM
fnp-3050	724	3	-	-	PUNCT
fnp-3050	724	4	1204	1204	NUM
fnp-3050	724	5	103	103	NUM
fnp-3050	724	6	.	.	PUNCT
fnp-3050	725	1	younas	younas	PROPN
fnp-3050	725	2	n	n	CCONJ
fnp-3050	725	3	,	,	PUNCT
fnp-3050	725	4	zafar	zafar	PROPN
fnp-3050	725	5	s	s	PROPN
fnp-3050	725	6	,	,	PUNCT
fnp-3050	725	7	shafiq	shafiq	PROPN
fnp-3050	725	8	m	m	PROPN
fnp-3050	725	9	,	,	PUNCT
fnp-3050	725	10	noor	noor	PROPN
fnp-3050	725	11	a	a	PROPN
fnp-3050	725	12	,	,	PUNCT
fnp-3050	725	13	siegert	siegert	PROPN
fnp-3050	725	14	a	a	PRON
fnp-3050	725	15	,	,	PUNCT
fnp-3050	725	16	arora	arora	PROPN
fnp-3050	725	17	as	as	ADP
fnp-3050	725	18	,	,	PUNCT
fnp-3050	725	19	galkin	galkin	PROPN
fnp-3050	725	20	a	a	X
fnp-3050	725	21	,	,	PUNCT
fnp-3050	725	22	zafar	zafar	PROPN
fnp-3050	725	23	a	a	PRON
fnp-3050	725	24	,	,	PUNCT
fnp-3050	725	25	schmitz	schmitz	PROPN
fnp-3050	725	26	m	m	PROPN
fnp-3050	725	27	,	,	PUNCT
fnp-3050	725	28	stadelmann	stadelmann	PROPN
fnp-3050	725	29	c	c	PROPN
fnp-3050	725	30	,	,	PUNCT
fnp-3050	725	31	andreoletti	andreoletti	PROPN
fnp-3050	725	32	o	o	NOUN
fnp-3050	725	33	,	,	PUNCT
fnp-3050	725	34	ferrer	ferrer	PROPN
fnp-3050	725	35	i	i	PROPN
fnp-3050	725	36	,	,	PUNCT
fnp-3050	725	37	zerr	zerr	PROPN
fnp-3050	725	38	i	i	PROPN
fnp-3050	725	39	(	(	PUNCT
fnp-3050	725	40	2020	2020	NUM
fnp-3050	725	41	)	)	PUNCT
fnp-3050	725	42	sfpq	sfpq	NOUN
fnp-3050	725	43	and	and	CCONJ
fnp-3050	725	44	tau	tau	NOUN
fnp-3050	725	45	:	:	PUNCT
fnp-3050	725	46	critical	critical	ADJ
fnp-3050	725	47	factors	factor	NOUN
fnp-3050	725	48	contributing	contribute	VERB
fnp-3050	725	49	to	to	ADP
fnp-3050	725	50	rapid	rapid	ADJ
fnp-3050	725	51	progression	progression	NOUN
fnp-3050	725	52	of	of	ADP
fnp-3050	725	53	alzheimer	alzheimer	PROPN
fnp-3050	725	54	's	's	PART
fnp-3050	725	55	disease	disease	NOUN
fnp-3050	725	56	.	.	PUNCT
fnp-3050	726	1	acta	acta	PROPN
fnp-3050	726	2	neuropathol	neuropathol	PROPN
fnp-3050	726	3	140:317	140:317	NUM
fnp-3050	726	4	-	-	SYM
fnp-3050	726	5	339	339	NUM
fnp-3050	726	6	104	104	NUM
fnp-3050	726	7	.	.	PUNCT
fnp-3050	727	1	mamun	mamun	PROPN
fnp-3050	727	2	aa	aa	PROPN
fnp-3050	727	3	,	,	PUNCT
fnp-3050	727	4	uddin	uddin	PROPN
fnp-3050	727	5	ms	ms	PROPN
fnp-3050	727	6	,	,	PUNCT
fnp-3050	727	7	mathew	mathew	PROPN
fnp-3050	727	8	b	b	PROPN
fnp-3050	727	9	,	,	PUNCT
fnp-3050	727	10	ashraf	ashraf	PROPN
fnp-3050	727	11	gm	gm	PROPN
fnp-3050	727	12	(	(	PUNCT
fnp-3050	727	13	2020	2020	NUM
fnp-3050	727	14	)	)	PUNCT
fnp-3050	728	1	toxic	toxic	ADJ
fnp-3050	728	2	tau	tau	PROPN
fnp-3050	728	3	:	:	PUNCT
fnp-3050	728	4	structural	structural	ADJ
fnp-3050	728	5	origins	origin	NOUN
fnp-3050	728	6	of	of	ADP
fnp-3050	728	7	tau	tau	PROPN
fnp-3050	728	8	aggregation	aggregation	NOUN
fnp-3050	728	9	in	in	ADP
fnp-3050	728	10	alzheimer	alzheimer	PROPN
fnp-3050	728	11	's	's	PART
fnp-3050	728	12	disease	disease	NOUN
fnp-3050	728	13	.	.	PUNCT
fnp-3050	729	1	neural	neural	PROPN
fnp-3050	729	2	regen	regen	PROPN
fnp-3050	729	3	res	re	NOUN
fnp-3050	729	4	15:1417	15:1417	NUM
fnp-3050	729	5	-	-	SYM
fnp-3050	729	6	1420	1420	NUM
fnp-3050	729	7	105	105	NUM
fnp-3050	729	8	.	.	PUNCT
fnp-3050	730	1	ballatore	ballatore	PROPN
fnp-3050	730	2	c	c	X
fnp-3050	730	3	,	,	PUNCT
fnp-3050	730	4	lee	lee	PROPN
fnp-3050	730	5	vm	vm	PROPN
fnp-3050	730	6	,	,	PUNCT
fnp-3050	730	7	trojanowski	trojanowski	PROPN
fnp-3050	730	8	jq	jq	PROPN
fnp-3050	730	9	(	(	PUNCT
fnp-3050	730	10	2007	2007	NUM
fnp-3050	730	11	)	)	PUNCT
fnp-3050	730	12	tau	tau	NOUN
fnp-3050	730	13	-	-	PUNCT
fnp-3050	730	14	mediated	mediate	VERB
fnp-3050	730	15	neurodegeneration	neurodegeneration	NOUN
fnp-3050	730	16	in	in	ADP
fnp-3050	730	17	alzheimer	alzheimer	PROPN
fnp-3050	730	18	's	's	PART
fnp-3050	730	19	disease	disease	NOUN
fnp-3050	730	20	and	and	CCONJ
fnp-3050	730	21	related	related	ADJ
fnp-3050	730	22	disorders	disorder	NOUN
fnp-3050	730	23	.	.	PUNCT
fnp-3050	731	1	nat	nat	PROPN
fnp-3050	731	2	rev	rev	PROPN
fnp-3050	731	3	neurosci	neurosci	PROPN
fnp-3050	731	4	8:663	8:663	NUM
fnp-3050	731	5	-	-	SYM
fnp-3050	731	6	672	672	NUM
fnp-3050	731	7	106	106	NUM
fnp-3050	731	8	.	.	PUNCT
fnp-3050	732	1	guha	guha	PROPN
fnp-3050	732	2	s	s	PROPN
fnp-3050	732	3	,	,	PUNCT
fnp-3050	732	4	johnson	johnson	PROPN
fnp-3050	732	5	gvw	gvw	PROPN
fnp-3050	732	6	,	,	PUNCT
fnp-3050	732	7	nehrke	nehrke	PROPN
fnp-3050	732	8	k	k	PROPN
fnp-3050	732	9	(	(	PUNCT
fnp-3050	732	10	2020	2020	NUM
fnp-3050	732	11	)	)	PUNCT
fnp-3050	732	12	the	the	DET
fnp-3050	732	13	crosstalk	crosstalk	NOUN
fnp-3050	732	14	between	between	ADP
fnp-3050	732	15	pathological	pathological	ADJ
fnp-3050	732	16	tau	tau	PROPN
fnp-3050	732	17	phosphorylation	phosphorylation	NOUN
fnp-3050	732	18	and	and	CCONJ
fnp-3050	732	19	mitochondrial	mitochondrial	ADJ
fnp-3050	732	20	dysfunction	dysfunction	NOUN
fnp-3050	732	21	as	as	ADP
fnp-3050	732	22	a	a	DET
fnp-3050	732	23	key	key	NOUN
fnp-3050	732	24	to	to	ADP
fnp-3050	732	25	understanding	understanding	NOUN
fnp-3050	732	26	and	and	CCONJ
fnp-3050	732	27	treating	treat	VERB
fnp-3050	732	28	alzheimer	alzheimer	NOUN
fnp-3050	732	29	's	's	PART
fnp-3050	732	30	disease	disease	NOUN
fnp-3050	732	31	.	.	PUNCT
fnp-3050	733	1	mol	mol	ADP
fnp-3050	733	2	neurobiol	neurobiol	PROPN
fnp-3050	733	3	57:5103	57:5103	NUM
fnp-3050	733	4	-	-	SYM
fnp-3050	733	5	5120	5120	NUM
fnp-3050	733	6	107	107	NUM
fnp-3050	733	7	.	.	PUNCT
fnp-3050	734	1	xia	xia	PROPN
fnp-3050	734	2	y	y	PROPN
fnp-3050	734	3	,	,	PUNCT
fnp-3050	734	4	prokop	prokop	PROPN
fnp-3050	734	5	s	s	PROPN
fnp-3050	734	6	,	,	PUNCT
fnp-3050	734	7	gorion	gorion	NOUN
fnp-3050	734	8	km	km	PROPN
fnp-3050	734	9	,	,	PUNCT
fnp-3050	734	10	kim	kim	PROPN
fnp-3050	734	11	jd	jd	PROPN
fnp-3050	734	12	,	,	PUNCT
fnp-3050	734	13	sorrentino	sorrentino	PROPN
fnp-3050	734	14	za	za	PROPN
fnp-3050	734	15	,	,	PUNCT
fnp-3050	734	16	bell	bell	PROPN
fnp-3050	734	17	bm	bm	PROPN
fnp-3050	734	18	,	,	PUNCT
fnp-3050	734	19	manaois	manaois	PROPN
fnp-3050	734	20	an	an	PRON
fnp-3050	734	21	,	,	PUNCT
fnp-3050	734	22	chakrabarty	chakrabarty	NOUN
fnp-3050	734	23	p	p	NOUN
fnp-3050	734	24	,	,	PUNCT
fnp-3050	734	25	davies	davy	NOUN
fnp-3050	734	26	p	p	NUM
fnp-3050	734	27	,	,	PUNCT
fnp-3050	734	28	giasson	giasson	ADJ
fnp-3050	734	29	bi	bi	NOUN
fnp-3050	734	30	(	(	PUNCT
fnp-3050	734	31	2020	2020	NUM
fnp-3050	734	32	)	)	PUNCT
fnp-3050	735	1	tau	tau	PROPN
fnp-3050	735	2	ser208	ser208	NOUN
fnp-3050	735	3	phosphorylation	phosphorylation	NOUN
fnp-3050	735	4	promotes	promote	VERB
fnp-3050	735	5	aggregation	aggregation	NOUN
fnp-3050	735	6	and	and	CCONJ
fnp-3050	735	7	reveals	reveal	VERB
fnp-3050	735	8	neuropathologic	neuropathologic	ADJ
fnp-3050	735	9	diversity	diversity	NOUN
fnp-3050	735	10	in	in	ADP
fnp-3050	735	11	alzheimer	alzheimer	PROPN
fnp-3050	735	12	's	's	PART
fnp-3050	735	13	disease	disease	NOUN
fnp-3050	735	14	and	and	CCONJ
fnp-3050	735	15	other	other	ADJ
fnp-3050	735	16	tauopathies	tauopathie	NOUN
fnp-3050	735	17	.	.	PUNCT
fnp-3050	736	1	acta	acta	PROPN
fnp-3050	736	2	neuropathol	neuropathol	PROPN
fnp-3050	736	3	commun	commun	PROPN
fnp-3050	736	4	8:88	8:88	NUM
fnp-3050	736	5	108	108	NUM
fnp-3050	736	6	.	.	PUNCT
fnp-3050	737	1	wischik	wischik	PROPN
fnp-3050	737	2	cm	cm	PROPN
fnp-3050	737	3	,	,	PUNCT
fnp-3050	737	4	novak	novak	PROPN
fnp-3050	737	5	m	m	PROPN
fnp-3050	737	6	,	,	PUNCT
fnp-3050	737	7	thogersen	thogersen	ADJ
fnp-3050	737	8	hc	hc	PROPN
fnp-3050	737	9	,	,	PUNCT
fnp-3050	737	10	edwards	edwards	PROPN
fnp-3050	737	11	pc	pc	PROPN
fnp-3050	737	12	,	,	PUNCT
fnp-3050	737	13	runswick	runswick	PROPN
fnp-3050	737	14	mj	mj	PROPN
fnp-3050	737	15	,	,	PUNCT
fnp-3050	737	16	jakes	jakes	PROPN
fnp-3050	737	17	r	r	PROPN
fnp-3050	737	18	,	,	PUNCT
fnp-3050	737	19	walker	walker	PROPN
fnp-3050	737	20	je	je	PROPN
fnp-3050	737	21	,	,	PUNCT
fnp-3050	737	22	milstein	milstein	ADP
fnp-3050	737	23	c	c	PROPN
fnp-3050	737	24	,	,	PUNCT
fnp-3050	737	25	roth	roth	PROPN
fnp-3050	737	26	m	m	PROPN
fnp-3050	737	27	,	,	PUNCT
fnp-3050	737	28	klug	klug	PROPN
fnp-3050	737	29	a	a	PROPN
fnp-3050	737	30	(	(	PUNCT
fnp-3050	737	31	1988	1988	NUM
fnp-3050	737	32	)	)	PUNCT
fnp-3050	737	33	isolation	isolation	NOUN
fnp-3050	737	34	of	of	ADP
fnp-3050	737	35	a	a	DET
fnp-3050	737	36	fragment	fragment	NOUN
fnp-3050	737	37	of	of	ADP
fnp-3050	737	38	tau	tau	PROPN
fnp-3050	737	39	derived	derive	VERB
fnp-3050	737	40	from	from	ADP
fnp-3050	737	41	the	the	DET
fnp-3050	737	42	core	core	NOUN
fnp-3050	737	43	of	of	ADP
fnp-3050	737	44	the	the	DET
fnp-3050	737	45	paired	pair	VERB
fnp-3050	737	46	helical	helical	ADJ
fnp-3050	737	47	filament	filament	NOUN
fnp-3050	737	48	of	of	ADP
fnp-3050	737	49	alzheimer	alzheimer	PROPN
fnp-3050	737	50	disease	disease	PROPN
fnp-3050	737	51	.	.	PUNCT
fnp-3050	738	1	proc	proc	PROPN
fnp-3050	738	2	natl	natl	PROPN
fnp-3050	738	3	acad	acad	PROPN
fnp-3050	738	4	sci	sci	PROPN
fnp-3050	738	5	u	u	PROPN
fnp-3050	738	6	s	s	PROPN
fnp-3050	738	7	a	a	DET
fnp-3050	738	8	85:4506	85:4506	NUM
fnp-3050	738	9	-	-	SYM
fnp-3050	738	10	4510	4510	NUM
fnp-3050	738	11	109	109	NUM
fnp-3050	738	12	.	.	PUNCT
fnp-3050	739	1	uchihara	uchihara	PROPN
fnp-3050	739	2	t	t	PROPN
fnp-3050	739	3	(	(	PUNCT
fnp-3050	739	4	2020	2020	NUM
fnp-3050	739	5	)	)	PUNCT
fnp-3050	739	6	neurofibrillary	neurofibrillary	ADJ
fnp-3050	739	7	changes	change	NOUN
fnp-3050	739	8	undergoing	undergo	VERB
fnp-3050	739	9	morphological	morphological	ADJ
fnp-3050	739	10	and	and	CCONJ
fnp-3050	739	11	biochemical	biochemical	ADJ
fnp-3050	739	12	changes	change	NOUN
fnp-3050	739	13	how	how	SCONJ
fnp-3050	739	14	does	do	AUX
fnp-3050	739	15	tau	tau	PROPN
fnp-3050	739	16	with	with	ADP
fnp-3050	739	17	the	the	DET
fnp-3050	739	18	profile	profile	ADJ
fnp-3050	739	19	shift	shift	NOUN
fnp-3050	739	20	of	of	ADP
fnp-3050	739	21	from	from	ADP
fnp-3050	739	22	four	four	NUM
fnp-3050	739	23	repeat	repeat	NOUN
fnp-3050	739	24	to	to	ADP
fnp-3050	739	25	three	three	NUM
fnp-3050	739	26	repeat	repeat	NOUN
fnp-3050	739	27	spread	spread	VERB
fnp-3050	739	28	in	in	ADP
fnp-3050	739	29	alzheimer	alzheimer	PROPN
fnp-3050	739	30	brain	brain	NOUN
fnp-3050	739	31	?	?	PUNCT
fnp-3050	740	1	neuropathology	neuropathology	NOUN
fnp-3050	741	1	online	online	ADV
fnp-3050	741	2	jul	jul	PROPN
fnp-3050	741	3	22	22	NUM
fnp-3050	741	4	:	:	PUNCT
fnp-3050	741	5	doi	doi	NOUN
fnp-3050	741	6	:	:	PUNCT
fnp-3050	741	7	10.1111	10.1111	NUM
fnp-3050	741	8	/	/	SYM
fnp-3050	741	9	neup.12669	neup.12669	PROPN
fnp-3050	741	10	110	110	NUM
fnp-3050	741	11	.	.	PUNCT
fnp-3050	742	1	kidd	kidd	PROPN
fnp-3050	742	2	m	m	PROPN
fnp-3050	742	3	(	(	PUNCT
fnp-3050	742	4	1964	1964	NUM
fnp-3050	742	5	)	)	PUNCT
fnp-3050	742	6	alzheimer	alzheimer	PROPN
fnp-3050	742	7	's	's	PART
fnp-3050	742	8	disease	disease	NOUN
fnp-3050	742	9	an	an	DET
fnp-3050	742	10	electron	electron	NOUN
fnp-3050	742	11	microscopical	microscopical	ADJ
fnp-3050	742	12	study	study	NOUN
fnp-3050	742	13	.	.	PUNCT
fnp-3050	743	1	brain	brain	NOUN
fnp-3050	743	2	87:307	87:307	NUM
fnp-3050	743	3	-	-	SYM
fnp-3050	743	4	320	320	NUM
fnp-3050	743	5	111	111	NUM
fnp-3050	743	6	.	.	PUNCT
fnp-3050	744	1	pollanen	pollanen	PROPN
fnp-3050	744	2	ms	ms	PROPN
fnp-3050	744	3	,	,	PUNCT
fnp-3050	744	4	markiewicz	markiewicz	NOUN
fnp-3050	744	5	p	p	X
fnp-3050	744	6	,	,	PUNCT
fnp-3050	744	7	bergeron	bergeron	PROPN
fnp-3050	744	8	c	c	PROPN
fnp-3050	744	9	,	,	PUNCT
fnp-3050	744	10	goh	goh	PROPN
fnp-3050	744	11	mc	mc	PROPN
fnp-3050	744	12	(	(	PUNCT
fnp-3050	744	13	1994	1994	NUM
fnp-3050	744	14	)	)	PUNCT
fnp-3050	744	15	twisted	twisted	ADJ
fnp-3050	744	16	ribbon	ribbon	NOUN
fnp-3050	744	17	structure	structure	NOUN
fnp-3050	744	18	of	of	ADP
fnp-3050	744	19	paired	pair	VERB
fnp-3050	744	20	helical	helical	ADJ
fnp-3050	744	21	filaments	filament	NOUN
fnp-3050	744	22	revealed	reveal	VERB
fnp-3050	744	23	by	by	ADP
fnp-3050	744	24	atomic	atomic	ADJ
fnp-3050	744	25	force	force	NOUN
fnp-3050	744	26	microscopy	microscopy	NOUN
fnp-3050	744	27	.	.	PUNCT
fnp-3050	744	28	am	be	AUX
fnp-3050	744	29	j	j	PROPN
fnp-3050	744	30	pathol	pathol	NOUN
fnp-3050	744	31	144:869	144:869	NOUN
fnp-3050	744	32	-	-	PUNCT
fnp-3050	744	33	873	873	NUM
fnp-3050	744	34	112	112	NUM
fnp-3050	744	35	.	.	PUNCT
fnp-3050	745	1	crowther	crowther	PROPN
fnp-3050	745	2	ra	ra	PROPN
fnp-3050	745	3	(	(	PUNCT
fnp-3050	745	4	1991	1991	NUM
fnp-3050	745	5	)	)	PUNCT
fnp-3050	745	6	straight	straight	ADJ
fnp-3050	745	7	and	and	CCONJ
fnp-3050	745	8	paired	pair	VERB
fnp-3050	745	9	helical	helical	ADJ
fnp-3050	745	10	filaments	filament	NOUN
fnp-3050	745	11	in	in	ADP
fnp-3050	745	12	alzheimer	alzheimer	PROPN
fnp-3050	745	13	disease	disease	NOUN
fnp-3050	745	14	have	have	VERB
fnp-3050	745	15	a	a	DET
fnp-3050	745	16	common	common	ADJ
fnp-3050	745	17	structural	structural	ADJ
fnp-3050	745	18	unit	unit	NOUN
fnp-3050	745	19	.	.	PUNCT
fnp-3050	746	1	proc	proc	PROPN
fnp-3050	746	2	natl	natl	PROPN
fnp-3050	746	3	acad	acad	PROPN
fnp-3050	746	4	sci	sci	PROPN
fnp-3050	746	5	u	u	PROPN
fnp-3050	746	6	s	s	PROPN
fnp-3050	746	7	a	a	DET
fnp-3050	746	8	88:2288	88:2288	ADJ
fnp-3050	746	9	-	-	SYM
fnp-3050	746	10	2292	2292	NUM
fnp-3050	746	11	113	113	NUM
fnp-3050	746	12	.	.	PUNCT
fnp-3050	747	1	fitzpatrick	fitzpatrick	PROPN
fnp-3050	747	2	awp	awp	PROPN
fnp-3050	747	3	,	,	PUNCT
fnp-3050	747	4	falcon	falcon	PROPN
fnp-3050	747	5	b	b	PROPN
fnp-3050	747	6	,	,	PUNCT
fnp-3050	747	7	he	he	PRON
fnp-3050	747	8	s	s	PROPN
fnp-3050	747	9	,	,	PUNCT
fnp-3050	747	10	murzin	murzin	PROPN
fnp-3050	747	11	ag	ag	PROPN
fnp-3050	747	12	,	,	PUNCT
fnp-3050	747	13	murshudov	murshudov	PROPN
fnp-3050	747	14	g	g	PROPN
fnp-3050	747	15	,	,	PUNCT
fnp-3050	747	16	garringer	garringer	PROPN
fnp-3050	747	17	hj	hj	PROPN
fnp-3050	747	18	,	,	PUNCT
fnp-3050	747	19	crowther	crowther	PROPN
fnp-3050	747	20	ra	ra	PROPN
fnp-3050	747	21	,	,	PUNCT
fnp-3050	747	22	ghetti	ghetti	PROPN
fnp-3050	747	23	b	b	PROPN
fnp-3050	747	24	,	,	PUNCT
fnp-3050	747	25	goedert	goedert	PROPN
fnp-3050	747	26	m	m	PRON
fnp-3050	747	27	,	,	PUNCT
fnp-3050	747	28	scheres	schere	NOUN
fnp-3050	747	29	shw	shw	PROPN
fnp-3050	747	30	(	(	PUNCT
fnp-3050	747	31	2017	2017	NUM
fnp-3050	747	32	)	)	PUNCT
fnp-3050	747	33	cryo	cryo	NOUN
fnp-3050	747	34	-	-	PUNCT
fnp-3050	747	35	em	em	PRON
fnp-3050	747	36	structures	structure	NOUN
fnp-3050	747	37	of	of	ADP
fnp-3050	747	38	tau	tau	PROPN
fnp-3050	747	39	filaments	filament	NOUN
fnp-3050	747	40	from	from	ADP
fnp-3050	747	41	alzheimer	alzheimer	PROPN
fnp-3050	747	42	's	's	PART
fnp-3050	747	43	disease	disease	NOUN
fnp-3050	747	44	.	.	PUNCT
fnp-3050	748	1	nature	nature	NOUN
fnp-3050	749	1	547:185	547:185	PROPN
fnp-3050	749	2	-	-	SYM
fnp-3050	749	3	190	190	NUM
fnp-3050	749	4	114	114	NUM
fnp-3050	749	5	.	.	PUNCT
fnp-3050	750	1	falcon	falcon	PROPN
fnp-3050	750	2	b	b	PROPN
fnp-3050	750	3	,	,	PUNCT
fnp-3050	750	4	zhang	zhang	PROPN
fnp-3050	750	5	w	w	PROPN
fnp-3050	750	6	,	,	PUNCT
fnp-3050	750	7	schweighauser	schweighauser	NOUN
fnp-3050	750	8	m	m	PROPN
fnp-3050	750	9	,	,	PUNCT
fnp-3050	750	10	murzin	murzin	PROPN
fnp-3050	750	11	ag	ag	PROPN
fnp-3050	750	12	,	,	PUNCT
fnp-3050	750	13	vidal	vidal	PROPN
fnp-3050	750	14	r	r	PROPN
fnp-3050	750	15	,	,	PUNCT
fnp-3050	750	16	garringer	garringer	NOUN
fnp-3050	750	17	hj	hj	PROPN
fnp-3050	750	18	,	,	PUNCT
fnp-3050	750	19	ghetti	ghetti	PROPN
fnp-3050	750	20	b	b	PROPN
fnp-3050	750	21	,	,	PUNCT
fnp-3050	750	22	scheres	schere	NOUN
fnp-3050	750	23	shw	shw	PROPN
fnp-3050	750	24	,	,	PUNCT
fnp-3050	750	25	goedert	goedert	PROPN
fnp-3050	750	26	m	m	PROPN
fnp-3050	750	27	(	(	PUNCT
fnp-3050	750	28	2018	2018	NUM
fnp-3050	750	29	)	)	PUNCT
fnp-3050	750	30	tau	tau	PROPN
fnp-3050	750	31	filaments	filament	VERB
fnp-3050	750	32	from	from	ADP
fnp-3050	750	33	multiple	multiple	ADJ
fnp-3050	750	34	cases	case	NOUN
fnp-3050	750	35	of	of	ADP
fnp-3050	750	36	sporadic	sporadic	ADJ
fnp-3050	750	37	and	and	CCONJ
fnp-3050	750	38	inherited	inherit	VERB
fnp-3050	750	39	alzheimer	alzheimer	PROPN
fnp-3050	750	40	's	's	PART
fnp-3050	750	41	disease	disease	NOUN
fnp-3050	750	42	adopt	adopt	VERB
fnp-3050	750	43	a	a	DET
fnp-3050	750	44	common	common	ADJ
fnp-3050	750	45	fold	fold	NOUN
fnp-3050	750	46	.	.	PUNCT
fnp-3050	751	1	acta	acta	PROPN
fnp-3050	751	2	neuropathol	neuropathol	PROPN
fnp-3050	751	3	136:699	136:699	PROPN
fnp-3050	751	4	-	-	PUNCT
fnp-3050	751	5	708	708	NUM
fnp-3050	751	6	115	115	NUM
fnp-3050	751	7	.	.	PUNCT
fnp-3050	752	1	braak	braak	PROPN
fnp-3050	752	2	e	e	NOUN
fnp-3050	752	3	,	,	PUNCT
fnp-3050	752	4	braak	braak	PROPN
fnp-3050	752	5	h	h	PROPN
fnp-3050	752	6	,	,	PUNCT
fnp-3050	752	7	mandelkow	mandelkow	VERB
fnp-3050	752	8	em	em	PRON
fnp-3050	752	9	(	(	PUNCT
fnp-3050	752	10	1994	1994	NUM
fnp-3050	752	11	)	)	PUNCT
fnp-3050	752	12	a	a	DET
fnp-3050	752	13	sequence	sequence	NOUN
fnp-3050	752	14	of	of	ADP
fnp-3050	752	15	cytoskeleton	cytoskeleton	NOUN
fnp-3050	752	16	changes	change	NOUN
fnp-3050	752	17	related	relate	VERB
fnp-3050	752	18	to	to	ADP
fnp-3050	752	19	the	the	DET
fnp-3050	752	20	formation	formation	NOUN
fnp-3050	752	21	of	of	ADP
fnp-3050	752	22	neurofibrillary	neurofibrillary	ADJ
fnp-3050	752	23	tangles	tangle	NOUN
fnp-3050	752	24	and	and	CCONJ
fnp-3050	752	25	neuropil	neuropil	NOUN
fnp-3050	752	26	threads	thread	NOUN
fnp-3050	752	27	.	.	PUNCT
fnp-3050	753	1	acta	acta	PROPN
fnp-3050	753	2	neuropathol	neuropathol	PROPN
fnp-3050	753	3	87:554	87:554	PROPN
fnp-3050	753	4	-	-	PUNCT
fnp-3050	753	5	567	567	NUM
fnp-3050	753	6	116	116	NUM
fnp-3050	753	7	.	.	PUNCT
fnp-3050	754	1	streit	streit	PROPN
fnp-3050	754	2	wj	wj	PROPN
fnp-3050	754	3	,	,	PUNCT
fnp-3050	754	4	khoshbouei	khoshbouei	PROPN
fnp-3050	754	5	h	h	PROPN
fnp-3050	754	6	,	,	PUNCT
fnp-3050	754	7	bechmann	bechmann	PROPN
fnp-3050	754	8	i	i	PRON
fnp-3050	754	9	(	(	PUNCT
fnp-3050	754	10	2020	2020	NUM
fnp-3050	754	11	)	)	PUNCT
fnp-3050	754	12	dystrophic	dystrophic	ADJ
fnp-3050	754	13	microglia	microglia	NOUN
fnp-3050	754	14	in	in	ADP
fnp-3050	754	15	late	late	ADJ
fnp-3050	754	16	-	-	PUNCT
fnp-3050	754	17	onset	onset	NOUN
fnp-3050	754	18	alzheimer	alzheimer	NOUN
fnp-3050	754	19	's	's	PART
fnp-3050	754	20	disease	disease	NOUN
fnp-3050	754	21	.	.	PUNCT
fnp-3050	755	1	glia	glia	PROPN
fnp-3050	755	2	68:845	68:845	PROPN
fnp-3050	755	3	-	-	PUNCT
fnp-3050	755	4	854	854	NUM
fnp-3050	755	5	117	117	NUM
fnp-3050	755	6	.	.	PUNCT
fnp-3050	756	1	malpas	malpas	PROPN
fnp-3050	756	2	cb	cb	PROPN
fnp-3050	756	3	,	,	PUNCT
fnp-3050	756	4	sharmin	sharmin	PROPN
fnp-3050	756	5	s	s	PROPN
fnp-3050	756	6	,	,	PUNCT
fnp-3050	756	7	kalincik	kalincik	PROPN
fnp-3050	756	8	t	t	PROPN
fnp-3050	756	9	(	(	PUNCT
fnp-3050	756	10	2020	2020	NUM
fnp-3050	756	11	)	)	PUNCT
fnp-3050	756	12	the	the	DET
fnp-3050	756	13	histopathological	histopathological	ADJ
fnp-3050	756	14	staging	staging	NOUN
fnp-3050	756	15	of	of	ADP
fnp-3050	756	16	tau	tau	PROPN
fnp-3050	756	17	,	,	PUNCT
fnp-3050	756	18	but	but	CCONJ
fnp-3050	756	19	not	not	PART
fnp-3050	756	20	amyloid	amyloid	NOUN
fnp-3050	756	21	,	,	PUNCT
fnp-3050	756	22	corresponds	correspond	VERB
fnp-3050	756	23	to	to	PART
fnp-3050	756	24	antemortem	antemortem	VERB
fnp-3050	756	25	cognitive	cognitive	ADJ
fnp-3050	756	26	status	status	NOUN
fnp-3050	756	27	,	,	PUNCT
fnp-3050	756	28	dementia	dementia	NOUN
fnp-3050	756	29	stage	stage	NOUN
fnp-3050	756	30	,	,	PUNCT
fnp-3050	756	31	functional	functional	ADJ
fnp-3050	756	32	abilities	ability	NOUN
fnp-3050	756	33	and	and	CCONJ
fnp-3050	756	34	neuropsychiatric	neuropsychiatric	ADJ
fnp-3050	756	35	symptoms	symptom	NOUN
fnp-3050	756	36	.	.	PUNCT
fnp-3050	757	1	int	int	PROPN
fnp-3050	757	2	j	j	PROPN
fnp-3050	757	3	neurosci	neurosci	PROPN
fnp-3050	757	4	apr	apr	VERB
fnp-3050	757	5	30	30	NUM
fnp-3050	757	6	:	:	PUNCT
fnp-3050	757	7	doi	doi	NOUN
fnp-3050	757	8	:	:	PUNCT
fnp-3050	757	9	10.1080/00207454.00202020.01758087	10.1080/00207454.00202020.01758087	NUM
fnp-3050	757	10	118	118	NUM
fnp-3050	757	11	.	.	PUNCT
fnp-3050	758	1	andrade	andrade	PROPN
fnp-3050	758	2	-	-	PUNCT
fnp-3050	758	3	moraes	moraes	PROPN
fnp-3050	758	4	ch	ch	PROPN
fnp-3050	758	5	,	,	PUNCT
fnp-3050	758	6	oliveira	oliveira	PROPN
fnp-3050	758	7	-	-	PUNCT
fnp-3050	758	8	pinto	pinto	NOUN
fnp-3050	758	9	av	av	PROPN
fnp-3050	758	10	,	,	PUNCT
fnp-3050	758	11	castro	castro	PROPN
fnp-3050	758	12	-	-	PUNCT
fnp-3050	758	13	fonseca	fonseca	PROPN
fnp-3050	758	14	e	e	PROPN
fnp-3050	758	15	,	,	PUNCT
fnp-3050	758	16	da	da	PROPN
fnp-3050	758	17	silva	silva	PROPN
fnp-3050	758	18	cg	cg	PROPN
fnp-3050	758	19	,	,	PUNCT
fnp-3050	758	20	guimaraes	guimaraes	PROPN
fnp-3050	758	21	dm	dm	PROPN
fnp-3050	758	22	,	,	PUNCT
fnp-3050	758	23	szczupak	szczupak	PROPN
fnp-3050	758	24	d	d	NOUN
fnp-3050	758	25	,	,	PUNCT
fnp-3050	758	26	parente	parente	PROPN
fnp-3050	758	27	-	-	PUNCT
fnp-3050	758	28	bruno	bruno	PROPN
fnp-3050	758	29	dr	dr	PROPN
fnp-3050	758	30	,	,	PUNCT
fnp-3050	758	31	carvalho	carvalho	PROPN
fnp-3050	758	32	lr	lr	PROPN
fnp-3050	758	33	,	,	PUNCT
fnp-3050	758	34	polichiso	polichiso	PROPN
fnp-3050	758	35	l	l	PROPN
fnp-3050	758	36	,	,	PUNCT
fnp-3050	758	37	gomes	gomes	PROPN
fnp-3050	758	38	bv	bv	PROPN
fnp-3050	758	39	,	,	PUNCT
fnp-3050	758	40	oliveira	oliveira	PROPN
fnp-3050	758	41	lm	lm	PROPN
fnp-3050	758	42	,	,	PUNCT
fnp-3050	758	43	rodriguez	rodriguez	PROPN
fnp-3050	758	44	rd	rd	PROPN
fnp-3050	758	45	,	,	PUNCT
fnp-3050	758	46	leite	leite	PROPN
fnp-3050	758	47	re	re	PROPN
fnp-3050	758	48	,	,	PUNCT
fnp-3050	758	49	ferretti	ferretti	NOUN
fnp-3050	758	50	-	-	PUNCT
fnp-3050	758	51	rebustini	rebustini	PROPN
fnp-3050	758	52	re	re	NOUN
fnp-3050	758	53	,	,	PUNCT
fnp-3050	758	54	jacob	jacob	PROPN
fnp-3050	758	55	-	-	PUNCT
fnp-3050	758	56	filho	filho	PROPN
fnp-3050	758	57	w	w	PROPN
fnp-3050	758	58	,	,	PUNCT
fnp-3050	758	59	pasqualucci	pasqualucci	NOUN
fnp-3050	758	60	ca	ca	PROPN
fnp-3050	758	61	,	,	PUNCT
fnp-3050	758	62	grinberg	grinberg	PROPN
fnp-3050	758	63	lt	lt	PROPN
fnp-3050	758	64	,	,	PUNCT
fnp-3050	758	65	lent	lend	VERB
fnp-3050	758	66	r	r	NOUN
fnp-3050	758	67	(	(	PUNCT
fnp-3050	758	68	2013	2013	NUM
fnp-3050	758	69	)	)	PUNCT
fnp-3050	758	70	cell	cell	NOUN
fnp-3050	758	71	number	number	NOUN
fnp-3050	758	72	changes	change	NOUN
fnp-3050	758	73	in	in	ADP
fnp-3050	758	74	alzheimer	alzheimer	PROPN
fnp-3050	758	75	's	's	PART
fnp-3050	758	76	disease	disease	NOUN
fnp-3050	758	77	relate	relate	VERB
fnp-3050	758	78	to	to	ADP
fnp-3050	758	79	dementia	dementia	NOUN
fnp-3050	758	80	,	,	PUNCT
fnp-3050	758	81	not	not	PART
fnp-3050	758	82	to	to	ADP
fnp-3050	758	83	plaques	plaque	NOUN
fnp-3050	758	84	and	and	CCONJ
fnp-3050	758	85	tangles	tangle	NOUN
fnp-3050	758	86	.	.	PUNCT
fnp-3050	759	1	brain	brain	NOUN
fnp-3050	759	2	136:3738	136:3738	NUM
fnp-3050	759	3	-	-	SYM
fnp-3050	759	4	3752	3752	NUM
fnp-3050	759	5	119	119	NUM
fnp-3050	759	6	.	.	PUNCT
fnp-3050	760	1	kuchibhotla	kuchibhotla	PROPN
fnp-3050	760	2	kv	kv	PROPN
fnp-3050	760	3	,	,	PUNCT
fnp-3050	760	4	wegmann	wegmann	PROPN
fnp-3050	760	5	s	s	PROPN
fnp-3050	760	6	,	,	PUNCT
fnp-3050	760	7	kopeikina	kopeikina	PROPN
fnp-3050	760	8	kj	kj	PROPN
fnp-3050	760	9	,	,	PUNCT
fnp-3050	760	10	hawkes	hawkes	PROPN
fnp-3050	760	11	j	j	PROPN
fnp-3050	760	12	,	,	PUNCT
fnp-3050	760	13	rudinskiy	rudinskiy	PROPN
fnp-3050	760	14	n	n	CCONJ
fnp-3050	760	15	,	,	PUNCT
fnp-3050	760	16	andermann	andermann	PROPN
fnp-3050	760	17	ml	ml	NOUN
fnp-3050	760	18	,	,	PUNCT
fnp-3050	760	19	spires	spire	NOUN
fnp-3050	760	20	-	-	PUNCT
fnp-3050	760	21	jones	jones	PROPN
fnp-3050	760	22	tl	tl	PROPN
fnp-3050	760	23	,	,	PUNCT
fnp-3050	760	24	bacskai	bacskai	ADJ
fnp-3050	760	25	bj	bj	NOUN
fnp-3050	760	26	,	,	PUNCT
fnp-3050	760	27	hyman	hyman	PROPN
fnp-3050	760	28	bt	bt	PROPN
fnp-3050	760	29	(	(	PUNCT
fnp-3050	760	30	2014	2014	NUM
fnp-3050	760	31	)	)	PUNCT
fnp-3050	760	32	neurofibrillary	neurofibrillary	ADJ
fnp-3050	760	33	tangle	tangle	NOUN
fnp-3050	760	34	-	-	PUNCT
fnp-3050	760	35	bearing	bear	VERB
fnp-3050	760	36	neurons	neuron	NOUN
fnp-3050	760	37	are	be	AUX
fnp-3050	760	38	functionally	functionally	ADV
fnp-3050	760	39	integrated	integrate	VERB
fnp-3050	760	40	in	in	ADP
fnp-3050	760	41	cortical	cortical	ADJ
fnp-3050	760	42	circuits	circuit	NOUN
fnp-3050	760	43	in	in	ADP
fnp-3050	760	44	vivo	vivo	NOUN
fnp-3050	760	45	.	.	PUNCT
fnp-3050	761	1	proc	proc	PROPN
fnp-3050	761	2	natl	natl	PROPN
fnp-3050	761	3	acad	acad	PROPN
fnp-3050	761	4	sci	sci	PROPN
fnp-3050	761	5	u	u	PROPN
fnp-3050	761	6	s	s	PROPN
fnp-3050	761	7	a	a	DET
fnp-3050	761	8	111:510	111:510	NOUN
fnp-3050	761	9	-	-	PUNCT
fnp-3050	761	10	514	514	NUM
fnp-3050	761	11	120	120	NUM
fnp-3050	761	12	.	.	PUNCT
fnp-3050	762	1	santacruz	santacruz	PROPN
fnp-3050	762	2	k	k	PROPN
fnp-3050	762	3	,	,	PUNCT
fnp-3050	762	4	lewis	lewis	PROPN
fnp-3050	762	5	j	j	PROPN
fnp-3050	762	6	,	,	PUNCT
fnp-3050	762	7	spires	spires	PROPN
fnp-3050	762	8	t	t	PROPN
fnp-3050	762	9	,	,	PUNCT
fnp-3050	762	10	paulson	paulson	PROPN
fnp-3050	762	11	j	j	PROPN
fnp-3050	762	12	,	,	PUNCT
fnp-3050	762	13	kotilinek	kotilinek	PROPN
fnp-3050	762	14	l	l	NOUN
fnp-3050	762	15	,	,	PUNCT
fnp-3050	762	16	ingelsson	ingelsson	PROPN
fnp-3050	762	17	m	m	PROPN
fnp-3050	762	18	,	,	PUNCT
fnp-3050	762	19	guimaraes	guimaraes	PROPN
fnp-3050	762	20	a	a	X
fnp-3050	762	21	,	,	PUNCT
fnp-3050	762	22	deture	deture	NOUN
fnp-3050	762	23	m	m	PROPN
fnp-3050	762	24	,	,	PUNCT
fnp-3050	762	25	ramsden	ramsden	PROPN
fnp-3050	762	26	m	m	PROPN
fnp-3050	762	27	,	,	PUNCT
fnp-3050	762	28	mcgowan	mcgowan	PROPN
fnp-3050	762	29	e	e	PROPN
fnp-3050	762	30	,	,	PUNCT
fnp-3050	762	31	forster	forster	PROPN
fnp-3050	762	32	c	c	PROPN
fnp-3050	762	33	,	,	PUNCT
fnp-3050	762	34	yue	yue	PROPN
fnp-3050	762	35	m	m	PROPN
fnp-3050	762	36	,	,	PUNCT
fnp-3050	762	37	orne	orne	PROPN
fnp-3050	762	38	j	j	PROPN
fnp-3050	762	39	,	,	PUNCT
fnp-3050	762	40	janus	janus	PROPN
fnp-3050	762	41	c	c	PROPN
fnp-3050	762	42	,	,	PUNCT
fnp-3050	762	43	mariash	mariash	VERB
fnp-3050	762	44	a	a	PRON
fnp-3050	762	45	,	,	PUNCT
fnp-3050	762	46	kuskowski	kuskowski	PROPN
fnp-3050	762	47	m	m	PROPN
fnp-3050	762	48	,	,	PUNCT
fnp-3050	762	49	hyman	hyman	PROPN
fnp-3050	762	50	b	b	PROPN
fnp-3050	762	51	,	,	PUNCT
fnp-3050	762	52	hutton	hutton	PROPN
fnp-3050	762	53	m	m	PROPN
fnp-3050	762	54	,	,	PUNCT
fnp-3050	762	55	ashe	ashe	PROPN
fnp-3050	762	56	kh	kh	PROPN
fnp-3050	762	57	(	(	PUNCT
fnp-3050	762	58	2005	2005	NUM
fnp-3050	762	59	)	)	PUNCT
fnp-3050	762	60	tau	tau	PROPN
fnp-3050	762	61	suppression	suppression	NOUN
fnp-3050	762	62	in	in	ADP
fnp-3050	762	63	a	a	DET
fnp-3050	762	64	neurodegenerative	neurodegenerative	ADJ
fnp-3050	762	65	mouse	mouse	NOUN
fnp-3050	762	66	model	model	NOUN
fnp-3050	762	67	improves	improve	VERB
fnp-3050	762	68	memory	memory	NOUN
fnp-3050	762	69	function	function	NOUN
fnp-3050	762	70	.	.	PUNCT
fnp-3050	763	1	science	science	NOUN
fnp-3050	763	2	309:476	309:476	PROPN
fnp-3050	763	3	-	-	SYM
fnp-3050	763	4	481	481	NUM
fnp-3050	763	5	121	121	NUM
fnp-3050	763	6	.	.	PUNCT
fnp-3050	764	1	spires	spires	PROPN
fnp-3050	764	2	tl	tl	PROPN
fnp-3050	764	3	,	,	PUNCT
fnp-3050	764	4	orne	orne	PROPN
fnp-3050	764	5	jd	jd	PROPN
fnp-3050	764	6	,	,	PUNCT
fnp-3050	764	7	santacruz	santacruz	PROPN
fnp-3050	764	8	k	k	PROPN
fnp-3050	764	9	,	,	PUNCT
fnp-3050	764	10	pitstick	pitstick	NOUN
fnp-3050	764	11	r	r	NOUN
fnp-3050	764	12	,	,	PUNCT
fnp-3050	764	13	carlson	carlson	PROPN
fnp-3050	764	14	ga	ga	PROPN
fnp-3050	764	15	,	,	PUNCT
fnp-3050	764	16	ashe	ashe	PROPN
fnp-3050	764	17	kh	kh	PROPN
fnp-3050	764	18	,	,	PUNCT
fnp-3050	764	19	hyman	hyman	PROPN
fnp-3050	764	20	bt	bt	PROPN
fnp-3050	764	21	(	(	PUNCT
fnp-3050	764	22	2006	2006	NUM
fnp-3050	764	23	)	)	PUNCT
fnp-3050	764	24	region	region	NOUN
fnp-3050	764	25	-	-	PUNCT
fnp-3050	764	26	specific	specific	ADJ
fnp-3050	764	27	dissociation	dissociation	NOUN
fnp-3050	764	28	of	of	ADP
fnp-3050	764	29	neuronal	neuronal	ADJ
fnp-3050	764	30	loss	loss	NOUN
fnp-3050	764	31	and	and	CCONJ
fnp-3050	764	32	neurofibrillary	neurofibrillary	ADJ
fnp-3050	764	33	pathology	pathology	NOUN
fnp-3050	764	34	in	in	ADP
fnp-3050	764	35	a	a	DET
fnp-3050	764	36	mouse	mouse	NOUN
fnp-3050	764	37	model	model	NOUN
fnp-3050	764	38	of	of	ADP
fnp-3050	764	39	tauopathy	tauopathy	NOUN
fnp-3050	764	40	.	.	PUNCT
fnp-3050	764	41	am	be	AUX
fnp-3050	764	42	j	j	PROPN
fnp-3050	764	43	pathol	pathol	NOUN
fnp-3050	764	44	168:1598	168:1598	PROPN
fnp-3050	764	45	-	-	PROPN
fnp-3050	764	46	1607	1607	NUM
fnp-3050	764	47	122	122	NUM
fnp-3050	764	48	.	.	PUNCT
fnp-3050	765	1	drummond	drummond	PROPN
fnp-3050	765	2	e	e	PROPN
fnp-3050	765	3	,	,	PUNCT
fnp-3050	765	4	pires	pire	VERB
fnp-3050	765	5	g	g	PROPN
fnp-3050	765	6	,	,	PUNCT
fnp-3050	765	7	macmurray	macmurray	PROPN
fnp-3050	765	8	c	c	PROPN
fnp-3050	765	9	,	,	PUNCT
fnp-3050	765	10	askenazi	askenazi	PROPN
fnp-3050	765	11	m	m	PROPN
fnp-3050	765	12	,	,	PUNCT
fnp-3050	765	13	nayak	nayak	PROPN
fnp-3050	765	14	s	s	PROPN
fnp-3050	765	15	,	,	PUNCT
fnp-3050	765	16	bourdon	bourdon	PROPN
fnp-3050	765	17	m	m	PROPN
fnp-3050	765	18	,	,	PUNCT
fnp-3050	765	19	safar	safar	PROPN
fnp-3050	765	20	j	j	PROPN
fnp-3050	765	21	,	,	PUNCT
fnp-3050	765	22	ueberheide	ueberheide	PROPN
fnp-3050	765	23	b	b	NOUN
fnp-3050	765	24	,	,	PUNCT
fnp-3050	765	25	wisniewski	wisniewski	PROPN
fnp-3050	765	26	t	t	PROPN
fnp-3050	765	27	(	(	PUNCT
fnp-3050	765	28	2020	2020	NUM
fnp-3050	765	29	)	)	PUNCT
fnp-3050	765	30	phosphorylated	phosphorylate	VERB
fnp-3050	765	31	tau	tau	NOUN
fnp-3050	765	32	interactome	interactome	NOUN
fnp-3050	765	33	in	in	ADP
fnp-3050	765	34	the	the	DET
fnp-3050	765	35	human	human	PROPN
fnp-3050	765	36	alzheimer	alzheimer	PROPN
fnp-3050	765	37	's	's	PART
fnp-3050	765	38	disease	disease	NOUN
fnp-3050	765	39	brain	brain	NOUN
fnp-3050	765	40	.	.	PUNCT
fnp-3050	766	1	brain	brain	NOUN
fnp-3050	766	2	143:2803	143:2803	NUM
fnp-3050	766	3	-	-	SYM
fnp-3050	766	4	2817	2817	NUM
fnp-3050	766	5	123	123	NUM
fnp-3050	766	6	.	.	PUNCT
fnp-3050	767	1	braak	braak	PROPN
fnp-3050	767	2	h	h	PROPN
fnp-3050	767	3	,	,	PUNCT
fnp-3050	767	4	del	del	PROPN
fnp-3050	767	5	tredici	tredici	PROPN
fnp-3050	767	6	k	k	PROPN
fnp-3050	767	7	(	(	PUNCT
fnp-3050	767	8	2011	2011	NUM
fnp-3050	767	9	)	)	PUNCT
fnp-3050	767	10	alzheimer	alzheimer	PROPN
fnp-3050	767	11	's	's	PART
fnp-3050	767	12	pathogenesis	pathogenesis	NOUN
fnp-3050	767	13	:	:	PUNCT
fnp-3050	767	14	is	be	AUX
fnp-3050	767	15	there	there	PRON
fnp-3050	767	16	neuron	neuron	NOUN
fnp-3050	767	17	-	-	PUNCT
fnp-3050	767	18	to	to	ADP
fnp-3050	767	19	-	-	PUNCT
fnp-3050	767	20	neuron	neuron	NOUN
fnp-3050	767	21	propagation	propagation	NOUN
fnp-3050	767	22	?	?	PUNCT
fnp-3050	768	1	acta	acta	PROPN
fnp-3050	768	2	neuropathol	neuropathol	PROPN
fnp-3050	768	3	121:589	121:589	PROPN
fnp-3050	768	4	-	-	SYM
fnp-3050	768	5	595	595	NUM
fnp-3050	768	6	124	124	NUM
fnp-3050	768	7	.	.	PUNCT
fnp-3050	769	1	clavaguera	clavaguera	NOUN
fnp-3050	769	2	f	f	PROPN
fnp-3050	769	3	,	,	PUNCT
fnp-3050	769	4	duyckaerts	duyckaert	NOUN
fnp-3050	769	5	c	c	PROPN
fnp-3050	769	6	,	,	PUNCT
fnp-3050	769	7	haik	haik	PROPN
fnp-3050	769	8	s	s	X
fnp-3050	769	9	(	(	PUNCT
fnp-3050	769	10	2020	2020	NUM
fnp-3050	769	11	)	)	PUNCT
fnp-3050	769	12	prion	prion	NOUN
fnp-3050	769	13	-	-	PUNCT
fnp-3050	769	14	like	like	ADJ
fnp-3050	769	15	properties	property	NOUN
fnp-3050	769	16	of	of	ADP
fnp-3050	769	17	tau	tau	PROPN
fnp-3050	769	18	assemblies	assembly	NOUN
fnp-3050	769	19	.	.	PUNCT
fnp-3050	770	1	curr	curr	PROPN
fnp-3050	770	2	opin	opin	PROPN
fnp-3050	770	3	neurobiol	neurobiol	PROPN
fnp-3050	770	4	61:49	61:49	NUM
fnp-3050	770	5	-	-	SYM
fnp-3050	770	6	57	57	NUM
fnp-3050	770	7	125	125	NUM
fnp-3050	770	8	.	.	PUNCT
fnp-3050	771	1	colin	colin	PROPN
fnp-3050	771	2	m	m	PROPN
fnp-3050	771	3	,	,	PUNCT
fnp-3050	771	4	dujardin	dujardin	PROPN
fnp-3050	771	5	s	s	PROPN
fnp-3050	771	6	,	,	PUNCT
fnp-3050	771	7	schraen	schraen	NOUN
fnp-3050	771	8	-	-	PUNCT
fnp-3050	771	9	maschke	maschke	NOUN
fnp-3050	771	10	s	s	NOUN
fnp-3050	771	11	,	,	PUNCT
fnp-3050	771	12	meno	meno	PROPN
fnp-3050	771	13	-	-	NOUN
fnp-3050	771	14	tetang	tetang	NOUN
fnp-3050	771	15	g	g	NOUN
fnp-3050	771	16	,	,	PUNCT
fnp-3050	771	17	duyckaerts	duyckaert	NOUN
fnp-3050	771	18	c	c	PROPN
fnp-3050	771	19	,	,	PUNCT
fnp-3050	771	20	courade	courade	PROPN
fnp-3050	771	21	jp	jp	NOUN
fnp-3050	771	22	,	,	PUNCT
fnp-3050	771	23	buee	buee	PROPN
fnp-3050	771	24	l	l	PROPN
fnp-3050	771	25	(	(	PUNCT
fnp-3050	771	26	2020	2020	NUM
fnp-3050	771	27	)	)	PUNCT
fnp-3050	771	28	from	from	ADP
fnp-3050	771	29	the	the	DET
fnp-3050	771	30	prion	prion	NOUN
fnp-3050	771	31	-	-	PUNCT
fnp-3050	771	32	like	like	ADJ
fnp-3050	771	33	propagation	propagation	NOUN
fnp-3050	771	34	hypothesis	hypothesis	NOUN
fnp-3050	771	35	to	to	ADP
fnp-3050	771	36	therapeutic	therapeutic	ADJ
fnp-3050	771	37	strategies	strategy	NOUN
fnp-3050	771	38	of	of	ADP
fnp-3050	771	39	anti	anti	ADJ
fnp-3050	771	40	-	-	ADJ
fnp-3050	771	41	tau	tau	ADJ
fnp-3050	771	42	immunotherapy	immunotherapy	NOUN
fnp-3050	771	43	.	.	PUNCT
fnp-3050	772	1	acta	acta	PROPN
fnp-3050	772	2	neuropathol	neuropathol	PROPN
fnp-3050	772	3	139:3	139:3	PROPN
fnp-3050	772	4	-	-	SYM
fnp-3050	772	5	25	25	NUM
fnp-3050	772	6	126	126	NUM
fnp-3050	772	7	.	.	PUNCT
fnp-3050	773	1	devos	devos	PROPN
fnp-3050	773	2	sl	sl	PROPN
fnp-3050	773	3	,	,	PUNCT
fnp-3050	773	4	corjuc	corjuc	VERB
fnp-3050	773	5	bt	bt	ADJ
fnp-3050	773	6	,	,	PUNCT
fnp-3050	773	7	oakley	oakley	PROPN
fnp-3050	773	8	dh	dh	PROPN
fnp-3050	773	9	,	,	PUNCT
fnp-3050	773	10	nobuhara	nobuhara	PROPN
fnp-3050	774	1	ck	ck	PROPN
fnp-3050	774	2	,	,	PUNCT
fnp-3050	774	3	bannon	bannon	PROPN
fnp-3050	774	4	rn	rn	PROPN
fnp-3050	774	5	,	,	PUNCT
fnp-3050	774	6	chase	chase	VERB
fnp-3050	774	7	a	a	PRON
fnp-3050	774	8	,	,	PUNCT
fnp-3050	774	9	commins	commin	NOUN
fnp-3050	774	10	c	c	PROPN
fnp-3050	774	11	,	,	PUNCT
fnp-3050	774	12	gonzalez	gonzalez	PROPN
fnp-3050	774	13	ja	ja	PROPN
fnp-3050	774	14	,	,	PUNCT
fnp-3050	774	15	dooley	dooley	PROPN
fnp-3050	774	16	pm	pm	PROPN
fnp-3050	774	17	,	,	PUNCT
fnp-3050	774	18	frosch	frosch	PROPN
fnp-3050	774	19	mp	mp	PROPN
fnp-3050	774	20	,	,	PUNCT
fnp-3050	774	21	hyman	hyman	PROPN
fnp-3050	774	22	bt	bt	PROPN
fnp-3050	774	23	(	(	PUNCT
fnp-3050	774	24	2018	2018	NUM
fnp-3050	774	25	)	)	PUNCT
fnp-3050	774	26	synaptic	synaptic	ADJ
fnp-3050	774	27	tau	tau	NOUN
fnp-3050	774	28	seeding	seed	VERB
fnp-3050	774	29	precedes	precede	VERB
fnp-3050	774	30	tau	tau	PROPN
fnp-3050	774	31	pathology	pathology	NOUN
fnp-3050	774	32	in	in	ADP
fnp-3050	774	33	human	human	PROPN
fnp-3050	774	34	alzheimer	alzheimer	PROPN
fnp-3050	774	35	's	's	PART
fnp-3050	774	36	disease	disease	NOUN
fnp-3050	774	37	brain	brain	NOUN
fnp-3050	774	38	.	.	PUNCT
fnp-3050	775	1	front	front	ADJ
fnp-3050	775	2	neurosci	neurosci	NOUN
fnp-3050	775	3	12:267	12:267	NUM
fnp-3050	775	4	127	127	NUM
fnp-3050	775	5	.	.	PUNCT
fnp-3050	776	1	dujardin	dujardin	PROPN
fnp-3050	776	2	s	s	PROPN
fnp-3050	776	3	,	,	PUNCT
fnp-3050	776	4	hyman	hyman	PROPN
fnp-3050	776	5	bt	bt	PROPN
fnp-3050	776	6	(	(	PUNCT
fnp-3050	776	7	2019	2019	NUM
fnp-3050	776	8	)	)	PUNCT
fnp-3050	776	9	tau	tau	PROPN
fnp-3050	776	10	prion	prion	NOUN
fnp-3050	776	11	-	-	PUNCT
fnp-3050	776	12	like	like	ADJ
fnp-3050	776	13	propagation	propagation	NOUN
fnp-3050	776	14	:	:	PUNCT
fnp-3050	776	15	state	state	NOUN
fnp-3050	776	16	of	of	ADP
fnp-3050	776	17	the	the	DET
fnp-3050	776	18	art	art	NOUN
fnp-3050	776	19	and	and	CCONJ
fnp-3050	776	20	current	current	ADJ
fnp-3050	776	21	challenges	challenge	NOUN
fnp-3050	776	22	.	.	PUNCT
fnp-3050	777	1	adv	adv	PROPN
fnp-3050	777	2	exp	exp	NOUN
fnp-3050	777	3	med	med	ADJ
fnp-3050	777	4	biol	biol	NOUN
fnp-3050	777	5	1184:305	1184:305	NUM
fnp-3050	777	6	-	-	SYM
fnp-3050	777	7	325	325	NUM
fnp-3050	777	8	128	128	NUM
fnp-3050	777	9	.	.	PUNCT
fnp-3050	777	10	stancu	stancu	PROPN
fnp-3050	777	11	ic	ic	PROPN
fnp-3050	777	12	,	,	PUNCT
fnp-3050	777	13	vasconcelos	vasconcelos	PROPN
fnp-3050	777	14	b	b	PROPN
fnp-3050	777	15	,	,	PUNCT
fnp-3050	777	16	ris	ris	PROPN
fnp-3050	777	17	l	l	PROPN
fnp-3050	777	18	,	,	PUNCT
fnp-3050	777	19	wang	wang	PROPN
fnp-3050	777	20	p	p	PROPN
fnp-3050	777	21	,	,	PUNCT
fnp-3050	777	22	villers	villers	PROPN
fnp-3050	777	23	a	a	PROPN
fnp-3050	777	24	,	,	PUNCT
fnp-3050	777	25	peeraer	peeraer	PROPN
fnp-3050	777	26	e	e	NOUN
fnp-3050	777	27	,	,	PUNCT
fnp-3050	777	28	buist	buist	VERB
fnp-3050	777	29	a	a	PRON
fnp-3050	777	30	,	,	PUNCT
fnp-3050	777	31	terwel	terwel	PROPN
fnp-3050	777	32	d	d	PROPN
fnp-3050	777	33	,	,	PUNCT
fnp-3050	777	34	baatsen	baatsen	NOUN
fnp-3050	777	35	p	p	SYM
fnp-3050	777	36	,	,	PUNCT
fnp-3050	777	37	oyelami	oyelami	PROPN
fnp-3050	777	38	t	t	PROPN
fnp-3050	777	39	,	,	PUNCT
fnp-3050	777	40	pierrot	pierrot	PROPN
fnp-3050	777	41	n	n	NUM
fnp-3050	777	42	,	,	PUNCT
fnp-3050	777	43	casteels	casteel	NOUN
fnp-3050	777	44	c	c	PROPN
fnp-3050	777	45	,	,	PUNCT
fnp-3050	777	46	bormans	borman	VERB
fnp-3050	777	47	g	g	NOUN
fnp-3050	777	48	,	,	PUNCT
fnp-3050	777	49	kienlen	kienlen	NOUN
fnp-3050	777	50	-	-	PUNCT
fnp-3050	777	51	campard	campard	NOUN
fnp-3050	777	52	p	p	NOUN
fnp-3050	777	53	,	,	PUNCT
fnp-3050	777	54	octave	octave	PROPN
fnp-3050	777	55	jn	jn	PROPN
fnp-3050	777	56	,	,	PUNCT
fnp-3050	777	57	moechars	moechar	NOUN
fnp-3050	777	58	d	d	PROPN
fnp-3050	777	59	,	,	PUNCT
fnp-3050	777	60	dewachter	dewachter	X
fnp-3050	778	1	i	i	PRON
fnp-3050	778	2	(	(	PUNCT
fnp-3050	778	3	2015	2015	NUM
fnp-3050	778	4	)	)	PUNCT
fnp-3050	778	5	templated	template	VERB
fnp-3050	778	6	misfolding	misfolding	NOUN
fnp-3050	778	7	of	of	ADP
fnp-3050	778	8	tau	tau	PROPN
fnp-3050	778	9	by	by	ADP
fnp-3050	778	10	prion	prion	NOUN
fnp-3050	778	11	-	-	PUNCT
fnp-3050	778	12	like	like	ADJ
fnp-3050	778	13	seeding	seeding	NOUN
fnp-3050	778	14	along	along	ADP
fnp-3050	778	15	neuronal	neuronal	ADJ
fnp-3050	778	16	connections	connection	NOUN
fnp-3050	778	17	impairs	impair	VERB
fnp-3050	778	18	neuronal	neuronal	ADJ
fnp-3050	778	19	network	network	NOUN
fnp-3050	778	20	function	function	NOUN
fnp-3050	778	21	and	and	CCONJ
fnp-3050	778	22	associated	associate	VERB
fnp-3050	778	23	behavioral	behavioral	ADJ
fnp-3050	778	24	outcomes	outcome	NOUN
fnp-3050	778	25	in	in	ADP
fnp-3050	778	26	tau	tau	PROPN
fnp-3050	778	27	transgenic	transgenic	NOUN
fnp-3050	778	28	mice	mouse	NOUN
fnp-3050	778	29	.	.	PUNCT
fnp-3050	779	1	acta	acta	PROPN
fnp-3050	779	2	neuropathol	neuropathol	PROPN
fnp-3050	779	3	129:875	129:875	PROPN
fnp-3050	779	4	-	-	PUNCT
fnp-3050	779	5	894	894	NUM
fnp-3050	779	6	129	129	NUM
fnp-3050	779	7	.	.	PUNCT
fnp-3050	780	1	narasimhan	narasimhan	PROPN
fnp-3050	780	2	s	s	PROPN
fnp-3050	780	3	,	,	PUNCT
fnp-3050	780	4	guo	guo	PROPN
fnp-3050	780	5	jl	jl	PROPN
fnp-3050	780	6	,	,	PUNCT
fnp-3050	780	7	changolkar	changolkar	PROPN
fnp-3050	780	8	l	l	NOUN
fnp-3050	780	9	,	,	PUNCT
fnp-3050	780	10	stieber	stieber	VERB
fnp-3050	780	11	a	a	PRON
fnp-3050	780	12	,	,	PUNCT
fnp-3050	780	13	mcbride	mcbride	PROPN
fnp-3050	780	14	jd	jd	PROPN
fnp-3050	780	15	,	,	PUNCT
fnp-3050	780	16	silva	silva	PROPN
fnp-3050	780	17	lv	lv	PROPN
fnp-3050	780	18	,	,	PUNCT
fnp-3050	780	19	he	he	PRON
fnp-3050	780	20	z	z	PROPN
fnp-3050	780	21	,	,	PUNCT
fnp-3050	780	22	zhang	zhang	PROPN
fnp-3050	780	23	b	b	PROPN
fnp-3050	780	24	,	,	PUNCT
fnp-3050	780	25	gathagan	gathagan	PROPN
fnp-3050	780	26	rj	rj	PROPN
fnp-3050	780	27	,	,	PUNCT
fnp-3050	780	28	trojanowski	trojanowski	PROPN
fnp-3050	780	29	jq	jq	PROPN
fnp-3050	780	30	,	,	PUNCT
fnp-3050	780	31	lee	lee	PROPN
fnp-3050	780	32	vmy	vmy	PROPN
fnp-3050	780	33	(	(	PUNCT
fnp-3050	780	34	2017	2017	NUM
fnp-3050	780	35	)	)	PUNCT
fnp-3050	780	36	pathological	pathological	ADJ
fnp-3050	780	37	tau	tau	NOUN
fnp-3050	780	38	strains	strain	VERB
fnp-3050	780	39	from	from	ADP
fnp-3050	780	40	human	human	ADJ
fnp-3050	780	41	brains	brain	NOUN
fnp-3050	780	42	recapitulate	recapitulate	VERB
fnp-3050	780	43	the	the	DET
fnp-3050	780	44	diversity	diversity	NOUN
fnp-3050	780	45	of	of	ADP
fnp-3050	780	46	tauopathies	tauopathie	NOUN
fnp-3050	780	47	in	in	ADP
fnp-3050	780	48	nontransgenic	nontransgenic	ADJ
fnp-3050	780	49	mouse	mouse	NOUN
fnp-3050	780	50	brain	brain	NOUN
fnp-3050	780	51	.	.	PUNCT
fnp-3050	781	1	j	j	PROPN
fnp-3050	781	2	neurosci	neurosci	PROPN
fnp-3050	781	3	37:11406	37:11406	NUM
fnp-3050	781	4	-	-	SYM
fnp-3050	781	5	11423	11423	NUM
fnp-3050	781	6	130	130	NUM
fnp-3050	781	7	.	.	PUNCT
fnp-3050	782	1	hopp	hopp	PROPN
fnp-3050	782	2	sc	sc	PROPN
fnp-3050	782	3	,	,	PUNCT
fnp-3050	782	4	lin	lin	PROPN
fnp-3050	782	5	y	y	PROPN
fnp-3050	782	6	,	,	PUNCT
fnp-3050	782	7	oakley	oakley	PROPN
fnp-3050	782	8	d	d	PROPN
fnp-3050	782	9	,	,	PUNCT
fnp-3050	782	10	roe	roe	NOUN
fnp-3050	782	11	ad	ad	NOUN
fnp-3050	782	12	,	,	PUNCT
fnp-3050	782	13	devos	devos	PROPN
fnp-3050	782	14	sl	sl	PROPN
fnp-3050	782	15	,	,	PUNCT
fnp-3050	782	16	hanlon	hanlon	NOUN
fnp-3050	782	17	d	d	PROPN
fnp-3050	782	18	,	,	PUNCT
fnp-3050	782	19	hyman	hyman	PROPN
fnp-3050	782	20	bt	bt	PROPN
fnp-3050	782	21	(	(	PUNCT
fnp-3050	782	22	2018	2018	NUM
fnp-3050	782	23	)	)	PUNCT
fnp-3050	782	24	the	the	DET
fnp-3050	782	25	role	role	NOUN
fnp-3050	782	26	of	of	ADP
fnp-3050	782	27	microglia	microglia	NOUN
fnp-3050	782	28	in	in	ADP
fnp-3050	782	29	processing	processing	NOUN
fnp-3050	782	30	and	and	CCONJ
fnp-3050	782	31	spreading	spread	VERB
fnp-3050	782	32	of	of	ADP
fnp-3050	782	33	bioactive	bioactive	PROPN
fnp-3050	782	34	tau	tau	PROPN
fnp-3050	782	35	seeds	seed	NOUN
fnp-3050	782	36	in	in	ADP
fnp-3050	782	37	alzheimer	alzheimer	PROPN
fnp-3050	782	38	's	's	PART
fnp-3050	782	39	disease	disease	NOUN
fnp-3050	782	40	.	.	PUNCT
fnp-3050	783	1	j	j	PROPN
fnp-3050	783	2	neuroinflammation	neuroinflammation	NOUN
fnp-3050	783	3	15:269	15:269	NUM
fnp-3050	783	4	131	131	NUM
fnp-3050	783	5	.	.	PUNCT
fnp-3050	784	1	furman	furman	PROPN
fnp-3050	784	2	jl	jl	PROPN
fnp-3050	784	3	,	,	PUNCT
fnp-3050	784	4	vaquer	vaquer	NOUN
fnp-3050	784	5	-	-	PUNCT
fnp-3050	784	6	alicea	alicea	PROPN
fnp-3050	784	7	j	j	PROPN
fnp-3050	784	8	,	,	PUNCT
fnp-3050	784	9	white	white	ADJ
fnp-3050	784	10	cl	cl	NOUN
fnp-3050	784	11	,	,	PUNCT
fnp-3050	784	12	3rd	3rd	NOUN
fnp-3050	784	13	,	,	PUNCT
fnp-3050	784	14	cairns	cairns	PROPN
fnp-3050	784	15	nj	nj	PROPN
fnp-3050	784	16	,	,	PUNCT
fnp-3050	784	17	nelson	nelson	PROPN
fnp-3050	784	18	pt	pt	PROPN
fnp-3050	784	19	,	,	PUNCT
fnp-3050	784	20	diamond	diamond	PROPN
fnp-3050	784	21	mi	mi	PROPN
fnp-3050	784	22	(	(	PUNCT
fnp-3050	784	23	2017	2017	NUM
fnp-3050	784	24	)	)	PUNCT
fnp-3050	784	25	widespread	widespread	ADJ
fnp-3050	784	26	tau	tau	NOUN
fnp-3050	784	27	seeding	seed	VERB
fnp-3050	784	28	activity	activity	NOUN
fnp-3050	784	29	at	at	ADP
fnp-3050	784	30	early	early	ADJ
fnp-3050	784	31	braak	braak	NOUN
fnp-3050	784	32	stages	stage	NOUN
fnp-3050	784	33	.	.	PUNCT
fnp-3050	785	1	acta	acta	PROPN
fnp-3050	785	2	neuropathol	neuropathol	PROPN
fnp-3050	785	3	133:91	133:91	NUM
fnp-3050	785	4	-	-	SYM
fnp-3050	785	5	100	100	NUM
fnp-3050	785	6	132	132	NUM
fnp-3050	785	7	.	.	PUNCT
fnp-3050	786	1	jagust	jagust	ADJ
fnp-3050	786	2	wj	wj	PROPN
fnp-3050	786	3	(	(	PUNCT
fnp-3050	786	4	2020	2020	NUM
fnp-3050	786	5	)	)	PUNCT
fnp-3050	786	6	imaging	imaging	NOUN
fnp-3050	786	7	tau	tau	PROPN
fnp-3050	786	8	pathology	pathology	NOUN
fnp-3050	786	9	the	the	DET
fnp-3050	786	10	next	next	ADJ
fnp-3050	786	11	step	step	NOUN
fnp-3050	786	12	.	.	PUNCT
fnp-3050	787	1	jama	jama	PROPN
fnp-3050	787	2	neurol	neurol	PROPN
fnp-3050	787	3	77:796	77:796	NUM
fnp-3050	787	4	-	-	SYM
fnp-3050	787	5	797	797	NUM
fnp-3050	787	6	133	133	NUM
fnp-3050	787	7	.	.	PUNCT
fnp-3050	788	1	lowe	lowe	PROPN
fnp-3050	788	2	vj	vj	PROPN
fnp-3050	788	3	,	,	PUNCT
fnp-3050	788	4	lundt	lundt	PROPN
fnp-3050	788	5	es	es	PROPN
fnp-3050	788	6	,	,	PUNCT
fnp-3050	788	7	albertson	albertson	PROPN
fnp-3050	788	8	sm	sm	PROPN
fnp-3050	788	9	,	,	PUNCT
fnp-3050	788	10	przybelski	przybelski	PROPN
fnp-3050	788	11	sa	sa	PROPN
fnp-3050	788	12	,	,	PUNCT
fnp-3050	788	13	senjem	senjem	NOUN
fnp-3050	788	14	ml	ml	PROPN
fnp-3050	788	15	,	,	PUNCT
fnp-3050	788	16	parisi	parisi	PROPN
fnp-3050	788	17	je	je	PROPN
fnp-3050	788	18	,	,	PUNCT
fnp-3050	788	19	kantarci	kantarci	PROPN
fnp-3050	788	20	k	k	PROPN
fnp-3050	788	21	,	,	PUNCT
fnp-3050	788	22	boeve	boeve	PROPN
fnp-3050	788	23	b	b	PROPN
fnp-3050	788	24	,	,	PUNCT
fnp-3050	788	25	jones	jones	PROPN
fnp-3050	788	26	dt	dt	PROPN
fnp-3050	788	27	,	,	PUNCT
fnp-3050	788	28	knopman	knopman	NOUN
fnp-3050	788	29	d	d	PROPN
fnp-3050	788	30	,	,	PUNCT
fnp-3050	788	31	jack	jack	PROPN
fnp-3050	788	32	cr	cr	PROPN
fnp-3050	788	33	,	,	PUNCT
fnp-3050	788	34	jr	jr	PROPN
fnp-3050	788	35	.	.	PROPN
fnp-3050	788	36	,	,	PUNCT
fnp-3050	788	37	dickson	dickson	PROPN
fnp-3050	788	38	dw	dw	PROPN
fnp-3050	788	39	,	,	PUNCT
fnp-3050	788	40	petersen	petersen	PROPN
fnp-3050	788	41	rc	rc	PROPN
fnp-3050	788	42	,	,	PUNCT
fnp-3050	788	43	murray	murray	VERB
fnp-3050	788	44	me	i	PRON
fnp-3050	788	45	(	(	PUNCT
fnp-3050	788	46	2019	2019	NUM
fnp-3050	788	47	)	)	PUNCT
fnp-3050	788	48	neuroimaging	neuroimaging	NOUN
fnp-3050	788	49	correlates	correlate	VERB
fnp-3050	788	50	with	with	ADP
fnp-3050	788	51	neuropathologic	neuropathologic	ADJ
fnp-3050	788	52	schemes	scheme	NOUN
fnp-3050	788	53	in	in	ADP
fnp-3050	788	54	neurodegenerative	neurodegenerative	ADJ
fnp-3050	788	55	disease	disease	NOUN
fnp-3050	788	56	.	.	PUNCT
fnp-3050	789	1	alzheimers	alzheimers	PROPN
fnp-3050	789	2	dement	dement	PROPN
fnp-3050	789	3	15:927	15:927	PROPN
fnp-3050	789	4	-	-	PUNCT
fnp-3050	789	5	939	939	NUM
fnp-3050	789	6	134	134	NUM
fnp-3050	789	7	.	.	PUNCT
fnp-3050	790	1	marquié	marquié	PROPN
fnp-3050	790	2	m	m	PROPN
fnp-3050	790	3	,	,	PUNCT
fnp-3050	790	4	siao	siao	PROPN
fnp-3050	790	5	tick	tick	PROPN
fnp-3050	790	6	chong	chong	PROPN
fnp-3050	790	7	m	m	PROPN
fnp-3050	790	8	,	,	PUNCT
fnp-3050	790	9	antón	antón	PROPN
fnp-3050	790	10	-	-	PUNCT
fnp-3050	790	11	fernández	fernández	PROPN
fnp-3050	790	12	a	a	PRON
fnp-3050	790	13	,	,	PUNCT
fnp-3050	790	14	verwer	verwer	NOUN
fnp-3050	790	15	ee	ee	PROPN
fnp-3050	790	16	,	,	PUNCT
fnp-3050	790	17	sáez	sáez	ADJ
fnp-3050	790	18	-	-	PUNCT
fnp-3050	790	19	calveras	calveras	PROPN
fnp-3050	790	20	n	n	CCONJ
fnp-3050	790	21	,	,	PUNCT
fnp-3050	790	22	meltzer	meltzer	PROPN
fnp-3050	790	23	ac	ac	PROPN
fnp-3050	790	24	,	,	PUNCT
fnp-3050	790	25	ramanan	ramanan	NOUN
fnp-3050	790	26	p	p	NOUN
fnp-3050	790	27	,	,	PUNCT
fnp-3050	790	28	amaral	amaral	PROPN
fnp-3050	790	29	ac	ac	PROPN
fnp-3050	790	30	,	,	PUNCT
fnp-3050	790	31	gonzalez	gonzalez	PROPN
fnp-3050	790	32	j	j	PROPN
fnp-3050	790	33	,	,	PUNCT
fnp-3050	790	34	normandin	normandin	PROPN
fnp-3050	790	35	md	md	PROPN
fnp-3050	790	36	,	,	PUNCT
fnp-3050	790	37	frosch	frosch	PROPN
fnp-3050	790	38	mp	mp	PROPN
fnp-3050	790	39	,	,	PUNCT
fnp-3050	790	40	gómez	gómez	PROPN
fnp-3050	790	41	-	-	PUNCT
fnp-3050	790	42	isla	isla	PROPN
fnp-3050	790	43	t	t	PROPN
fnp-3050	790	44	(	(	PUNCT
fnp-3050	790	45	2017	2017	NUM
fnp-3050	790	46	)	)	PUNCT
fnp-3050	791	1	[	[	X
fnp-3050	791	2	f-18]-av-1451	f-18]-av-1451	NOUN
fnp-3050	791	3	binding	binding	NOUN
fnp-3050	791	4	correlates	correlate	VERB
fnp-3050	791	5	with	with	ADP
fnp-3050	791	6	postmortem	postmortem	NOUN
fnp-3050	791	7	neurofibrillary	neurofibrillary	PROPN
fnp-3050	791	8	tangle	tangle	NOUN
fnp-3050	791	9	braak	braak	NOUN
fnp-3050	791	10	staging	staging	NOUN
fnp-3050	791	11	.	.	PUNCT
fnp-3050	792	1	acta	acta	PROPN
fnp-3050	792	2	neuropathol	neuropathol	PROPN
fnp-3050	792	3	134:619	134:619	NUM
fnp-3050	792	4	-	-	SYM
fnp-3050	792	5	628	628	NUM
fnp-3050	792	6	135	135	NUM
fnp-3050	792	7	.	.	PUNCT
fnp-3050	793	1	ossenkoppele	ossenkoppele	PROPN
fnp-3050	793	2	r	r	PROPN
fnp-3050	793	3	,	,	PUNCT
fnp-3050	793	4	schonhaut	schonhaut	PROPN
fnp-3050	793	5	dr	dr	PROPN
fnp-3050	793	6	,	,	PUNCT
fnp-3050	793	7	schöll	schöll	PROPN
fnp-3050	793	8	m	m	PROPN
fnp-3050	793	9	,	,	PUNCT
fnp-3050	793	10	lockhart	lockhart	PROPN
fnp-3050	793	11	sn	sn	PROPN
fnp-3050	793	12	,	,	PUNCT
fnp-3050	793	13	ayakta	ayakta	PROPN
fnp-3050	793	14	n	n	CCONJ
fnp-3050	793	15	,	,	PUNCT
fnp-3050	793	16	baker	baker	PROPN
fnp-3050	793	17	sl	sl	PROPN
fnp-3050	793	18	,	,	PUNCT
fnp-3050	793	19	o'neil	o'neil	PROPN
fnp-3050	793	20	jp	jp	PROPN
fnp-3050	793	21	,	,	PUNCT
fnp-3050	793	22	janabi	janabi	PROPN
fnp-3050	793	23	m	m	PROPN
fnp-3050	793	24	,	,	PUNCT
fnp-3050	793	25	lazaris	lazaris	PROPN
fnp-3050	793	26	a	a	PROPN
fnp-3050	793	27	,	,	PUNCT
fnp-3050	793	28	cantwell	cantwell	PROPN
fnp-3050	793	29	a	a	PROPN
fnp-3050	793	30	,	,	PUNCT
fnp-3050	793	31	vogel	vogel	PROPN
fnp-3050	793	32	j	j	PROPN
fnp-3050	793	33	,	,	PUNCT
fnp-3050	793	34	santos	santos	PROPN
fnp-3050	793	35	m	m	PROPN
fnp-3050	793	36	,	,	PUNCT
fnp-3050	793	37	miller	miller	PROPN
fnp-3050	793	38	za	za	PROPN
fnp-3050	793	39	,	,	PUNCT
fnp-3050	793	40	bettcher	bettcher	PROPN
fnp-3050	793	41	bm	bm	PROPN
fnp-3050	793	42	,	,	PUNCT
fnp-3050	793	43	vossel	vossel	PROPN
fnp-3050	793	44	ka	ka	PROPN
fnp-3050	793	45	,	,	PUNCT
fnp-3050	793	46	kramer	kramer	PROPN
fnp-3050	793	47	jh	jh	PROPN
fnp-3050	793	48	,	,	PUNCT
fnp-3050	793	49	gorno	gorno	PROPN
fnp-3050	793	50	-	-	PUNCT
fnp-3050	793	51	tempini	tempini	PROPN
fnp-3050	793	52	ml	ml	PROPN
fnp-3050	793	53	,	,	PUNCT
fnp-3050	793	54	miller	miller	PROPN
fnp-3050	793	55	bl	bl	PROPN
fnp-3050	793	56	,	,	PUNCT
fnp-3050	793	57	jagust	jagust	PROPN
fnp-3050	793	58	wj	wj	PROPN
fnp-3050	793	59	,	,	PUNCT
fnp-3050	793	60	rabinovici	rabinovici	NOUN
fnp-3050	793	61	gd	gd	PROPN
fnp-3050	793	62	(	(	PUNCT
fnp-3050	793	63	2016	2016	NUM
fnp-3050	793	64	)	)	PUNCT
fnp-3050	794	1	tau	tau	PROPN
fnp-3050	794	2	pet	pet	ADJ
fnp-3050	794	3	patterns	pattern	NOUN
fnp-3050	794	4	mirror	mirror	VERB
fnp-3050	794	5	clinical	clinical	ADJ
fnp-3050	794	6	and	and	CCONJ
fnp-3050	794	7	neuroanatomical	neuroanatomical	ADJ
fnp-3050	794	8	variability	variability	NOUN
fnp-3050	794	9	in	in	ADP
fnp-3050	794	10	alzheimer	alzheimer	PROPN
fnp-3050	794	11	's	's	PART
fnp-3050	794	12	disease	disease	NOUN
fnp-3050	794	13	.	.	PUNCT
fnp-3050	795	1	brain	brain	NOUN
fnp-3050	795	2	139:1551	139:1551	NUM
fnp-3050	795	3	-	-	SYM
fnp-3050	795	4	1567	1567	NUM
fnp-3050	795	5	136	136	NUM
fnp-3050	795	6	.	.	PUNCT
fnp-3050	796	1	schwarz	schwarz	PROPN
fnp-3050	796	2	aj	aj	PROPN
fnp-3050	796	3	,	,	PUNCT
fnp-3050	796	4	yu	yu	PROPN
fnp-3050	796	5	p	p	PROPN
fnp-3050	796	6	,	,	PUNCT
fnp-3050	796	7	miller	miller	PROPN
fnp-3050	796	8	bb	bb	PROPN
fnp-3050	796	9	,	,	PUNCT
fnp-3050	796	10	shcherbinin	shcherbinin	ADP
fnp-3050	796	11	s	s	PROPN
fnp-3050	796	12	,	,	PUNCT
fnp-3050	796	13	dickson	dickson	PROPN
fnp-3050	796	14	j	j	PROPN
fnp-3050	796	15	,	,	PUNCT
fnp-3050	796	16	navitsky	navitsky	PROPN
fnp-3050	796	17	m	m	PROPN
fnp-3050	796	18	,	,	PUNCT
fnp-3050	796	19	joshi	joshi	PROPN
fnp-3050	796	20	ad	ad	NOUN
fnp-3050	796	21	,	,	PUNCT
fnp-3050	796	22	devous	devous	PROPN
fnp-3050	796	23	md	md	PROPN
fnp-3050	796	24	,	,	PUNCT
fnp-3050	796	25	sr	sr	PROPN
fnp-3050	796	26	.	.	PROPN
fnp-3050	796	27	,	,	PUNCT
fnp-3050	796	28	mintun	mintun	PROPN
fnp-3050	796	29	ms	ms	PROPN
fnp-3050	796	30	(	(	PUNCT
fnp-3050	796	31	2016	2016	NUM
fnp-3050	796	32	)	)	PUNCT
fnp-3050	796	33	regional	regional	ADJ
fnp-3050	796	34	profiles	profile	NOUN
fnp-3050	796	35	of	of	ADP
fnp-3050	796	36	the	the	DET
fnp-3050	796	37	candidate	candidate	NOUN
fnp-3050	796	38	tau	tau	PROPN
fnp-3050	796	39	pet	pet	PROPN
fnp-3050	796	40	ligand	ligand	PROPN
fnp-3050	796	41	18f	18f	PROPN
fnp-3050	796	42	-	-	PUNCT
fnp-3050	796	43	av-1451	av-1451	PROPN
fnp-3050	796	44	recapitulate	recapitulate	VERB
fnp-3050	796	45	key	key	ADJ
fnp-3050	796	46	features	feature	NOUN
fnp-3050	796	47	of	of	ADP
fnp-3050	796	48	braak	braak	ADJ
fnp-3050	796	49	histopathological	histopathological	ADJ
fnp-3050	796	50	stages	stage	NOUN
fnp-3050	796	51	.	.	PUNCT
fnp-3050	797	1	brain	brain	NOUN
fnp-3050	797	2	139:1539	139:1539	NUM
fnp-3050	797	3	-	-	SYM
fnp-3050	797	4	1550	1550	NUM
fnp-3050	797	5	137	137	NUM
fnp-3050	797	6	.	.	PUNCT
fnp-3050	798	1	vogels	vogels	PROPN
fnp-3050	798	2	t	t	PROPN
fnp-3050	798	3	,	,	PUNCT
fnp-3050	798	4	leuzy	leuzy	VERB
fnp-3050	798	5	a	a	PRON
fnp-3050	798	6	,	,	PUNCT
fnp-3050	798	7	cicognola	cicognola	PROPN
fnp-3050	798	8	c	c	NOUN
fnp-3050	798	9	,	,	PUNCT
fnp-3050	798	10	ashton	ashton	PROPN
fnp-3050	798	11	nj	nj	PROPN
fnp-3050	798	12	,	,	PUNCT
fnp-3050	798	13	smolek	smolek	PROPN
fnp-3050	798	14	t	t	PROPN
fnp-3050	798	15	,	,	PUNCT
fnp-3050	798	16	novak	novak	PROPN
fnp-3050	798	17	m	m	PROPN
fnp-3050	798	18	,	,	PUNCT
fnp-3050	798	19	blennow	blennow	ADV
fnp-3050	798	20	k	k	PROPN
fnp-3050	798	21	,	,	PUNCT
fnp-3050	798	22	zetterberg	zetterberg	PROPN
fnp-3050	798	23	h	h	PROPN
fnp-3050	798	24	,	,	PUNCT
fnp-3050	798	25	hromadka	hromadka	PROPN
fnp-3050	798	26	t	t	PROPN
fnp-3050	798	27	,	,	PUNCT
fnp-3050	798	28	zilka	zilka	NOUN
fnp-3050	798	29	n	n	CCONJ
fnp-3050	798	30	,	,	PUNCT
fnp-3050	798	31	schöll	schöll	VERB
fnp-3050	798	32	m	m	PROPN
fnp-3050	798	33	(	(	PUNCT
fnp-3050	798	34	2020	2020	NUM
fnp-3050	798	35	)	)	PUNCT
fnp-3050	798	36	propagation	propagation	NOUN
fnp-3050	798	37	of	of	ADP
fnp-3050	798	38	tau	tau	PROPN
fnp-3050	798	39	pathology	pathology	NOUN
fnp-3050	798	40	:	:	PUNCT
fnp-3050	798	41	integrating	integrate	VERB
fnp-3050	798	42	insights	insight	NOUN
fnp-3050	798	43	from	from	ADP
fnp-3050	798	44	postmortem	postmortem	NOUN
fnp-3050	798	45	and	and	CCONJ
fnp-3050	798	46	in	in	ADP
fnp-3050	798	47	vivo	vivo	ADJ
fnp-3050	798	48	studies	study	NOUN
fnp-3050	798	49	.	.	PUNCT
fnp-3050	799	1	biol	biol	PROPN
fnp-3050	799	2	psychiatry	psychiatry	PROPN
fnp-3050	799	3	87:808	87:808	PROPN
fnp-3050	799	4	-	-	PUNCT
fnp-3050	799	5	818	818	NUM
fnp-3050	799	6	138	138	NUM
fnp-3050	799	7	.	.	PUNCT
fnp-3050	799	8	arriagada	arriagada	PROPN
fnp-3050	799	9	pv	pv	PROPN
fnp-3050	799	10	,	,	PUNCT
fnp-3050	799	11	growdon	growdon	VERB
fnp-3050	799	12	jh	jh	PROPN
fnp-3050	799	13	,	,	PUNCT
fnp-3050	799	14	hedley	hedley	PROPN
fnp-3050	799	15	-	-	PUNCT
fnp-3050	799	16	whyte	whyte	PROPN
fnp-3050	799	17	et	et	PROPN
fnp-3050	799	18	,	,	PUNCT
fnp-3050	799	19	hyman	hyman	PROPN
fnp-3050	799	20	bt	bt	PROPN
fnp-3050	799	21	(	(	PUNCT
fnp-3050	799	22	1992	1992	NUM
fnp-3050	799	23	)	)	PUNCT
fnp-3050	799	24	neurofibrillary	neurofibrillary	ADJ
fnp-3050	799	25	tangles	tangle	NOUN
fnp-3050	799	26	but	but	CCONJ
fnp-3050	799	27	not	not	PART
fnp-3050	799	28	senile	senile	ADJ
fnp-3050	799	29	plaques	plaque	NOUN
fnp-3050	799	30	parallel	parallel	ADJ
fnp-3050	799	31	duration	duration	NOUN
fnp-3050	799	32	and	and	CCONJ
fnp-3050	799	33	severity	severity	NOUN
fnp-3050	799	34	of	of	ADP
fnp-3050	799	35	alzheimer	alzheimer	PROPN
fnp-3050	799	36	's	's	PART
fnp-3050	799	37	disease	disease	NOUN
fnp-3050	799	38	.	.	PUNCT
fnp-3050	800	1	neurology	neurology	NOUN
fnp-3050	800	2	42:631	42:631	PROPN
fnp-3050	800	3	-	-	PUNCT
fnp-3050	800	4	639	639	NUM
fnp-3050	800	5	139	139	NUM
fnp-3050	800	6	.	.	PUNCT
fnp-3050	801	1	nelson	nelson	PROPN
fnp-3050	801	2	pt	pt	PROPN
fnp-3050	801	3	,	,	PUNCT
fnp-3050	801	4	alafuzoff	alafuzoff	NOUN
fnp-3050	802	1	i	i	PRON
fnp-3050	802	2	,	,	PUNCT
fnp-3050	802	3	bigio	bigio	NOUN
fnp-3050	802	4	eh	eh	INTJ
fnp-3050	802	5	,	,	PUNCT
fnp-3050	802	6	bouras	boura	NOUN
fnp-3050	802	7	c	c	NOUN
fnp-3050	802	8	,	,	PUNCT
fnp-3050	802	9	braak	braak	PROPN
fnp-3050	802	10	h	h	PROPN
fnp-3050	802	11	,	,	PUNCT
fnp-3050	802	12	cairns	cairns	PROPN
fnp-3050	802	13	nj	nj	PROPN
fnp-3050	802	14	,	,	PUNCT
fnp-3050	802	15	castellani	castellani	PROPN
fnp-3050	802	16	rj	rj	PROPN
fnp-3050	802	17	,	,	PUNCT
fnp-3050	802	18	crain	crain	PROPN
fnp-3050	802	19	bj	bj	PROPN
fnp-3050	802	20	,	,	PUNCT
fnp-3050	802	21	davies	davy	NOUN
fnp-3050	802	22	p	p	NOUN
fnp-3050	802	23	,	,	PUNCT
fnp-3050	802	24	del	del	PROPN
fnp-3050	802	25	tredici	tredici	PROPN
fnp-3050	802	26	k	k	PROPN
fnp-3050	802	27	,	,	PUNCT
fnp-3050	802	28	duyckaerts	duyckaert	NOUN
fnp-3050	802	29	c	c	PROPN
fnp-3050	802	30	,	,	PUNCT
fnp-3050	802	31	frosch	frosch	PROPN
fnp-3050	802	32	mp	mp	PROPN
fnp-3050	802	33	,	,	PUNCT
fnp-3050	802	34	haroutunian	haroutunian	PROPN
fnp-3050	802	35	v	v	PROPN
fnp-3050	802	36	,	,	PUNCT
fnp-3050	802	37	hof	hof	PROPN
fnp-3050	802	38	pr	pr	PROPN
fnp-3050	802	39	,	,	PUNCT
fnp-3050	802	40	hulette	hulette	PROPN
fnp-3050	802	41	cm	cm	PROPN
fnp-3050	802	42	,	,	PUNCT
fnp-3050	802	43	hyman	hyman	PROPN
fnp-3050	802	44	bt	bt	PROPN
fnp-3050	802	45	,	,	PUNCT
fnp-3050	802	46	iwatsubo	iwatsubo	PROPN
fnp-3050	802	47	t	t	PROPN
fnp-3050	802	48	,	,	PUNCT
fnp-3050	802	49	jellinger	jellinger	PROPN
fnp-3050	802	50	ka	ka	PROPN
fnp-3050	802	51	,	,	PUNCT
fnp-3050	802	52	jicha	jicha	PROPN
fnp-3050	802	53	ga	ga	PROPN
fnp-3050	802	54	,	,	PUNCT
fnp-3050	802	55	kovari	kovari	PROPN
fnp-3050	802	56	e	e	PROPN
fnp-3050	802	57	,	,	PUNCT
fnp-3050	802	58	kukull	kukull	PROPN
fnp-3050	802	59	wa	wa	PROPN
fnp-3050	802	60	,	,	PUNCT
fnp-3050	802	61	leverenz	leverenz	PROPN
fnp-3050	802	62	jb	jb	PROPN
fnp-3050	802	63	,	,	PUNCT
fnp-3050	802	64	love	love	NOUN
fnp-3050	802	65	s	s	PROPN
fnp-3050	802	66	,	,	PUNCT
fnp-3050	802	67	mackenzie	mackenzie	PROPN
fnp-3050	802	68	ir	ir	PROPN
fnp-3050	802	69	,	,	PUNCT
fnp-3050	802	70	mann	mann	PROPN
fnp-3050	802	71	dm	dm	PROPN
fnp-3050	802	72	,	,	PUNCT
fnp-3050	802	73	masliah	masliah	PROPN
fnp-3050	802	74	e	e	PROPN
fnp-3050	802	75	,	,	PUNCT
fnp-3050	802	76	mckee	mckee	PROPN
fnp-3050	802	77	ac	ac	PROPN
fnp-3050	802	78	,	,	PUNCT
fnp-3050	802	79	montine	montine	PROPN
fnp-3050	802	80	tj	tj	PROPN
fnp-3050	802	81	,	,	PUNCT
fnp-3050	802	82	morris	morris	PROPN
fnp-3050	802	83	jc	jc	PROPN
fnp-3050	802	84	,	,	PUNCT
fnp-3050	802	85	schneider	schneider	PROPN
fnp-3050	802	86	ja	ja	PROPN
fnp-3050	802	87	,	,	PUNCT
fnp-3050	802	88	sonnen	sonnen	PROPN
fnp-3050	802	89	ja	ja	PROPN
fnp-3050	802	90	,	,	PUNCT
fnp-3050	802	91	thal	thal	PROPN
fnp-3050	802	92	dr	dr	PROPN
fnp-3050	802	93	,	,	PUNCT
fnp-3050	802	94	trojanowski	trojanowski	PROPN
fnp-3050	802	95	jq	jq	PROPN
fnp-3050	802	96	,	,	PUNCT
fnp-3050	802	97	troncoso	troncoso	PROPN
fnp-3050	802	98	jc	jc	PROPN
fnp-3050	802	99	,	,	PUNCT
fnp-3050	802	100	wisniewski	wisniewski	PROPN
fnp-3050	802	101	t	t	PROPN
fnp-3050	802	102	,	,	PUNCT
fnp-3050	802	103	woltjer	woltjer	ADJ
fnp-3050	802	104	rl	rl	PROPN
fnp-3050	802	105	,	,	PUNCT
fnp-3050	802	106	beach	beach	NOUN
fnp-3050	802	107	tg	tg	PROPN
fnp-3050	802	108	(	(	PUNCT
fnp-3050	802	109	2012	2012	NUM
fnp-3050	802	110	)	)	PUNCT
fnp-3050	802	111	correlation	correlation	NOUN
fnp-3050	802	112	of	of	ADP
fnp-3050	802	113	alzheimer	alzheimer	PROPN
fnp-3050	802	114	disease	disease	PROPN
fnp-3050	802	115	neuropathologic	neuropathologic	NOUN
fnp-3050	802	116	changes	change	NOUN
fnp-3050	802	117	with	with	ADP
fnp-3050	802	118	cognitive	cognitive	ADJ
fnp-3050	802	119	status	status	NOUN
fnp-3050	802	120	:	:	PUNCT
fnp-3050	802	121	a	a	DET
fnp-3050	802	122	review	review	NOUN
fnp-3050	802	123	of	of	ADP
fnp-3050	802	124	the	the	DET
fnp-3050	802	125	literature	literature	NOUN
fnp-3050	802	126	.	.	PUNCT
fnp-3050	803	1	j	j	PROPN
fnp-3050	803	2	neuropathol	neuropathol	PROPN
fnp-3050	803	3	exp	exp	PROPN
fnp-3050	803	4	neurol	neurol	PROPN
fnp-3050	803	5	71:362	71:362	NUM
fnp-3050	803	6	-	-	SYM
fnp-3050	803	7	381	381	NUM
fnp-3050	803	8	140	140	NUM
fnp-3050	803	9	.	.	PUNCT
fnp-3050	803	10	ohm	ohm	PROPN
fnp-3050	803	11	dt	dt	PROPN
fnp-3050	803	12	,	,	PUNCT
fnp-3050	803	13	fought	fight	VERB
fnp-3050	803	14	aj	aj	PROPN
fnp-3050	803	15	,	,	PUNCT
fnp-3050	803	16	rademaker	rademaker	VERB
fnp-3050	803	17	a	a	NOUN
fnp-3050	803	18	,	,	PUNCT
fnp-3050	803	19	kim	kim	PROPN
fnp-3050	803	20	g	g	PROPN
fnp-3050	803	21	,	,	PUNCT
fnp-3050	803	22	sridhar	sridhar	PROPN
fnp-3050	803	23	j	j	PROPN
fnp-3050	803	24	,	,	PUNCT
fnp-3050	803	25	coventry	coventry	PROPN
fnp-3050	803	26	c	c	PROPN
fnp-3050	803	27	,	,	PUNCT
fnp-3050	803	28	gefen	gefen	PROPN
fnp-3050	803	29	t	t	PROPN
fnp-3050	803	30	,	,	PUNCT
fnp-3050	803	31	weintraub	weintraub	PROPN
fnp-3050	803	32	s	s	PROPN
fnp-3050	803	33	,	,	PUNCT
fnp-3050	803	34	bigio	bigio	NOUN
fnp-3050	803	35	e	e	NOUN
fnp-3050	803	36	,	,	PUNCT
fnp-3050	803	37	mesulam	mesulam	PROPN
fnp-3050	803	38	mm	mm	PROPN
fnp-3050	803	39	,	,	PUNCT
fnp-3050	803	40	rogalski	rogalski	NOUN
fnp-3050	803	41	e	e	PROPN
fnp-3050	803	42	,	,	PUNCT
fnp-3050	803	43	geula	geula	PROPN
fnp-3050	803	44	c	c	X
fnp-3050	803	45	(	(	PUNCT
fnp-3050	803	46	2020	2020	NUM
fnp-3050	803	47	)	)	PUNCT
fnp-3050	803	48	neuropathologic	neuropathologic	ADJ
fnp-3050	803	49	basis	basis	NOUN
fnp-3050	803	50	of	of	ADP
fnp-3050	803	51	in	in	ADP
fnp-3050	803	52	vivo	vivo	ADJ
fnp-3050	803	53	cortical	cortical	ADJ
fnp-3050	803	54	atrophy	atrophy	NOUN
fnp-3050	803	55	in	in	ADP
fnp-3050	803	56	the	the	DET
fnp-3050	803	57	aphasic	aphasic	ADJ
fnp-3050	803	58	variant	variant	NOUN
fnp-3050	803	59	of	of	ADP
fnp-3050	803	60	alzheimer	alzheimer	PROPN
fnp-3050	803	61	's	's	PART
fnp-3050	803	62	disease	disease	NOUN
fnp-3050	803	63	.	.	PUNCT
fnp-3050	804	1	brain	brain	NOUN
fnp-3050	804	2	pathol	pathol	NOUN
fnp-3050	804	3	30:332	30:332	NUM
fnp-3050	804	4	-	-	SYM
fnp-3050	804	5	344	344	NUM
fnp-3050	804	6	141	141	NUM
fnp-3050	804	7	.	.	PUNCT
fnp-3050	805	1	kaufman	kaufman	PROPN
fnp-3050	805	2	sk	sk	PROPN
fnp-3050	805	3	,	,	PUNCT
fnp-3050	805	4	del	del	PROPN
fnp-3050	805	5	tredici	tredici	PROPN
fnp-3050	805	6	k	k	PROPN
fnp-3050	805	7	,	,	PUNCT
fnp-3050	805	8	thomas	thomas	PROPN
fnp-3050	805	9	tl	tl	PROPN
fnp-3050	805	10	,	,	PUNCT
fnp-3050	805	11	braak	braak	PROPN
fnp-3050	805	12	h	h	PROPN
fnp-3050	805	13	,	,	PUNCT
fnp-3050	805	14	diamond	diamond	PROPN
fnp-3050	805	15	mi	mi	PROPN
fnp-3050	805	16	(	(	PUNCT
fnp-3050	805	17	2018	2018	NUM
fnp-3050	805	18	)	)	PUNCT
fnp-3050	806	1	tau	tau	NOUN
fnp-3050	806	2	seeding	seed	VERB
fnp-3050	806	3	activity	activity	NOUN
fnp-3050	806	4	begins	begin	VERB
fnp-3050	806	5	in	in	ADP
fnp-3050	806	6	the	the	DET
fnp-3050	806	7	transentorhinal	transentorhinal	ADJ
fnp-3050	806	8	/	/	SYM
fnp-3050	806	9	entorhinal	entorhinal	ADJ
fnp-3050	806	10	regions	region	NOUN
fnp-3050	806	11	and	and	CCONJ
fnp-3050	806	12	anticipates	anticipate	VERB
fnp-3050	806	13	phospho	phospho	ADJ
fnp-3050	806	14	-	-	PUNCT
fnp-3050	806	15	tau	tau	NOUN
fnp-3050	806	16	pathology	pathology	NOUN
fnp-3050	806	17	in	in	ADP
fnp-3050	806	18	alzheimer	alzheimer	PROPN
fnp-3050	806	19	's	's	PART
fnp-3050	806	20	disease	disease	NOUN
fnp-3050	806	21	and	and	CCONJ
fnp-3050	806	22	part	part	NOUN
fnp-3050	806	23	.	.	PUNCT
fnp-3050	807	1	acta	acta	PROPN
fnp-3050	807	2	neuropathol	neuropathol	PROPN
fnp-3050	807	3	136:57	136:57	PROPN
fnp-3050	807	4	-	-	SYM
fnp-3050	807	5	67	67	NUM
fnp-3050	807	6	142	142	NUM
fnp-3050	807	7	.	.	PUNCT
fnp-3050	808	1	attems	attem	VERB
fnp-3050	808	2	j	j	PROPN
fnp-3050	808	3	,	,	PUNCT
fnp-3050	808	4	thomas	thomas	PROPN
fnp-3050	808	5	a	a	PROPN
fnp-3050	808	6	,	,	PUNCT
fnp-3050	808	7	jellinger	jellinger	PROPN
fnp-3050	808	8	k	k	PROPN
fnp-3050	808	9	(	(	PUNCT
fnp-3050	808	10	2012	2012	NUM
fnp-3050	808	11	)	)	PUNCT
fnp-3050	808	12	correlations	correlation	NOUN
fnp-3050	808	13	between	between	ADP
fnp-3050	808	14	cortical	cortical	ADJ
fnp-3050	808	15	and	and	CCONJ
fnp-3050	808	16	subcortical	subcortical	ADJ
fnp-3050	808	17	tau	tau	PROPN
fnp-3050	808	18	pathology	pathology	NOUN
fnp-3050	808	19	.	.	PUNCT
fnp-3050	809	1	neuropathol	neuropathol	PROPN
fnp-3050	809	2	appl	appl	PROPN
fnp-3050	809	3	neurobiol	neurobiol	PROPN
fnp-3050	809	4	38:582	38:582	PROPN
fnp-3050	809	5	-	-	SYM
fnp-3050	809	6	590	590	NUM
fnp-3050	809	7	143	143	NUM
fnp-3050	809	8	.	.	PUNCT
fnp-3050	810	1	braak	braak	PROPN
fnp-3050	810	2	h	h	PROPN
fnp-3050	810	3	,	,	PUNCT
fnp-3050	810	4	thal	thal	PROPN
fnp-3050	810	5	dr	dr	PROPN
fnp-3050	810	6	,	,	PUNCT
fnp-3050	810	7	ghebremedhin	ghebremedhin	NOUN
fnp-3050	810	8	e	e	NOUN
fnp-3050	810	9	,	,	PUNCT
fnp-3050	810	10	del	del	PROPN
fnp-3050	810	11	tredici	tredici	PROPN
fnp-3050	810	12	k	k	PROPN
fnp-3050	810	13	(	(	PUNCT
fnp-3050	810	14	2011	2011	NUM
fnp-3050	810	15	)	)	PUNCT
fnp-3050	810	16	stages	stage	NOUN
fnp-3050	810	17	of	of	ADP
fnp-3050	810	18	the	the	DET
fnp-3050	810	19	pathologic	pathologic	ADJ
fnp-3050	810	20	process	process	NOUN
fnp-3050	810	21	in	in	ADP
fnp-3050	810	22	alzheimer	alzheimer	PROPN
fnp-3050	810	23	disease	disease	NOUN
fnp-3050	810	24	:	:	PUNCT
fnp-3050	810	25	age	age	NOUN
fnp-3050	810	26	categories	category	NOUN
fnp-3050	810	27	from	from	ADP
fnp-3050	810	28	1	1	NUM
fnp-3050	810	29	to	to	PART
fnp-3050	810	30	100	100	NUM
fnp-3050	810	31	years	year	NOUN
fnp-3050	810	32	.	.	PUNCT
fnp-3050	811	1	j	j	PROPN
fnp-3050	811	2	neuropathol	neuropathol	PROPN
fnp-3050	811	3	exp	exp	PROPN
fnp-3050	811	4	neurol	neurol	PROPN
fnp-3050	811	5	70:960	70:960	PROPN
fnp-3050	811	6	-	-	SYM
fnp-3050	811	7	969	969	NUM
fnp-3050	811	8	144	144	NUM
fnp-3050	811	9	.	.	PUNCT
fnp-3050	812	1	grinberg	grinberg	PROPN
fnp-3050	812	2	lt	lt	PROPN
fnp-3050	812	3	,	,	PUNCT
fnp-3050	812	4	rüb	rüb	PROPN
fnp-3050	812	5	u	u	PROPN
fnp-3050	812	6	,	,	PUNCT
fnp-3050	812	7	ferretti	ferretti	PROPN
fnp-3050	812	8	re	re	PROPN
fnp-3050	812	9	,	,	PUNCT
fnp-3050	812	10	nitrini	nitrini	PROPN
fnp-3050	812	11	r	r	NOUN
fnp-3050	812	12	,	,	PUNCT
fnp-3050	812	13	farfel	farfel	PROPN
fnp-3050	812	14	jm	jm	PROPN
fnp-3050	812	15	,	,	PUNCT
fnp-3050	812	16	polichiso	polichiso	NOUN
fnp-3050	812	17	l	l	PROPN
fnp-3050	812	18	,	,	PUNCT
fnp-3050	812	19	gierga	gierga	PROPN
fnp-3050	812	20	k	k	PROPN
fnp-3050	812	21	,	,	PUNCT
fnp-3050	812	22	jacob	jacob	PROPN
fnp-3050	812	23	-	-	PUNCT
fnp-3050	812	24	filho	filho	PROPN
fnp-3050	812	25	w	w	PROPN
fnp-3050	812	26	,	,	PUNCT
fnp-3050	812	27	heinsen	heinsen	ADJ
fnp-3050	812	28	h	h	PROPN
fnp-3050	812	29	(	(	PUNCT
fnp-3050	812	30	2009	2009	NUM
fnp-3050	812	31	)	)	PUNCT
fnp-3050	812	32	the	the	DET
fnp-3050	812	33	dorsal	dorsal	NOUN
fnp-3050	812	34	raphe	raphe	NOUN
fnp-3050	812	35	nucleus	nucleus	PROPN
fnp-3050	812	36	shows	show	VERB
fnp-3050	812	37	phospho	phospho	ADJ
fnp-3050	812	38	-	-	PUNCT
fnp-3050	812	39	tau	tau	NOUN
fnp-3050	812	40	neurofibrillary	neurofibrillary	ADJ
fnp-3050	812	41	changes	change	NOUN
fnp-3050	812	42	before	before	ADP
fnp-3050	812	43	the	the	DET
fnp-3050	812	44	transentorhinal	transentorhinal	ADJ
fnp-3050	812	45	region	region	NOUN
fnp-3050	812	46	in	in	ADP
fnp-3050	812	47	alzheimer	alzheimer	PROPN
fnp-3050	812	48	's	's	PART
fnp-3050	812	49	disease	disease	NOUN
fnp-3050	812	50	.	.	PUNCT
fnp-3050	813	1	a	a	DET
fnp-3050	813	2	precocious	precocious	ADJ
fnp-3050	813	3	onset	onset	NOUN
fnp-3050	813	4	?	?	PUNCT
fnp-3050	814	1	neuropathol	neuropathol	NOUN
fnp-3050	814	2	appl	appl	PROPN
fnp-3050	814	3	neurobiol	neurobiol	PROPN
fnp-3050	814	4	35:406	35:406	NUM
fnp-3050	814	5	-	-	SYM
fnp-3050	814	6	416	416	NUM
fnp-3050	814	7	145	145	NUM
fnp-3050	814	8	.	.	PUNCT
fnp-3050	815	1	braak	braak	PROPN
fnp-3050	815	2	h	h	PROPN
fnp-3050	815	3	,	,	PUNCT
fnp-3050	815	4	del	del	PROPN
fnp-3050	815	5	trecidi	trecidi	PROPN
fnp-3050	815	6	k	k	PROPN
fnp-3050	815	7	(	(	PUNCT
fnp-3050	815	8	2015	2015	NUM
fnp-3050	815	9	)	)	PUNCT
fnp-3050	815	10	neuroanatomy	neuroanatomy	NOUN
fnp-3050	815	11	and	and	CCONJ
fnp-3050	815	12	pathology	pathology	NOUN
fnp-3050	815	13	of	of	ADP
fnp-3050	815	14	sporadic	sporadic	ADJ
fnp-3050	815	15	alzheimer	alzheimer	PROPN
fnp-3050	815	16	's	's	PART
fnp-3050	815	17	disease	disease	NOUN
fnp-3050	815	18	.	.	PUNCT
fnp-3050	816	1	adv	adv	PROPN
fnp-3050	816	2	anat	anat	PROPN
fnp-3050	816	3	embryol	embryol	PROPN
fnp-3050	816	4	cell	cell	PROPN
fnp-3050	816	5	biol	biol	PROPN
fnp-3050	816	6	215:1	215:1	NUM
fnp-3050	816	7	-	-	SYM
fnp-3050	816	8	162	162	NUM
fnp-3050	816	9	146	146	NUM
fnp-3050	816	10	.	.	PUNCT
fnp-3050	817	1	grudzien	grudzien	PROPN
fnp-3050	817	2	a	a	DET
fnp-3050	817	3	,	,	PUNCT
fnp-3050	817	4	shaw	shaw	PROPN
fnp-3050	817	5	p	p	PROPN
fnp-3050	817	6	,	,	PUNCT
fnp-3050	817	7	weintraub	weintraub	PROPN
fnp-3050	817	8	s	s	PROPN
fnp-3050	817	9	,	,	PUNCT
fnp-3050	817	10	bigio	bigio	NOUN
fnp-3050	817	11	e	e	NOUN
fnp-3050	817	12	,	,	PUNCT
fnp-3050	817	13	mash	mash	NOUN
fnp-3050	817	14	dc	dc	PROPN
fnp-3050	817	15	,	,	PUNCT
fnp-3050	817	16	mesulam	mesulam	PROPN
fnp-3050	817	17	mm	mm	PROPN
fnp-3050	817	18	(	(	PUNCT
fnp-3050	817	19	2007	2007	NUM
fnp-3050	817	20	)	)	PUNCT
fnp-3050	817	21	locus	locus	NOUN
fnp-3050	817	22	coeruleus	coeruleus	NOUN
fnp-3050	817	23	neurofibrillary	neurofibrillary	ADJ
fnp-3050	817	24	degeneration	degeneration	NOUN
fnp-3050	817	25	in	in	ADP
fnp-3050	817	26	aging	age	VERB
fnp-3050	817	27	,	,	PUNCT
fnp-3050	817	28	mild	mild	ADJ
fnp-3050	817	29	cognitive	cognitive	ADJ
fnp-3050	817	30	impairment	impairment	NOUN
fnp-3050	817	31	and	and	CCONJ
fnp-3050	817	32	early	early	ADJ
fnp-3050	817	33	alzheimer	alzheimer	PROPN
fnp-3050	817	34	's	's	PART
fnp-3050	817	35	disease	disease	NOUN
fnp-3050	817	36	.	.	PUNCT
fnp-3050	818	1	neurobiol	neurobiol	PROPN
fnp-3050	818	2	aging	age	VERB
fnp-3050	818	3	28:327	28:327	NUM
fnp-3050	818	4	-	-	SYM
fnp-3050	818	5	335	335	NUM
fnp-3050	818	6	147	147	NUM
fnp-3050	818	7	.	.	PUNCT
fnp-3050	819	1	rüb	rüb	PROPN
fnp-3050	819	2	u	u	PROPN
fnp-3050	819	3	,	,	PUNCT
fnp-3050	819	4	stratmann	stratmann	PROPN
fnp-3050	819	5	k	k	X
fnp-3050	819	6	,	,	PUNCT
fnp-3050	819	7	heinsen	heinsen	PROPN
fnp-3050	819	8	h	h	PROPN
fnp-3050	819	9	,	,	PUNCT
fnp-3050	819	10	turco	turco	PROPN
fnp-3050	819	11	dd	dd	PROPN
fnp-3050	819	12	,	,	PUNCT
fnp-3050	819	13	seidel	seidel	PROPN
fnp-3050	819	14	k	k	PROPN
fnp-3050	819	15	,	,	PUNCT
fnp-3050	819	16	dunnen	dunnen	PROPN
fnp-3050	819	17	w	w	PROPN
fnp-3050	819	18	,	,	PUNCT
fnp-3050	819	19	korf	korf	PROPN
fnp-3050	819	20	hw	hw	PROPN
fnp-3050	819	21	(	(	PUNCT
fnp-3050	819	22	2016	2016	NUM
fnp-3050	819	23	)	)	PUNCT
fnp-3050	819	24	the	the	DET
fnp-3050	819	25	brainstem	brainstem	NOUN
fnp-3050	819	26	tau	tau	VERB
fnp-3050	819	27	cytoskeletal	cytoskeletal	ADJ
fnp-3050	819	28	pathology	pathology	NOUN
fnp-3050	819	29	of	of	ADP
fnp-3050	819	30	alzheimer	alzheimer	PROPN
fnp-3050	819	31	's	's	PART
fnp-3050	819	32	disease	disease	NOUN
fnp-3050	819	33	:	:	PUNCT
fnp-3050	819	34	a	a	DET
fnp-3050	819	35	brief	brief	ADJ
fnp-3050	819	36	historical	historical	ADJ
fnp-3050	819	37	overview	overview	NOUN
fnp-3050	819	38	and	and	CCONJ
fnp-3050	819	39	description	description	NOUN
fnp-3050	819	40	of	of	ADP
fnp-3050	819	41	its	its	PRON
fnp-3050	819	42	anatomical	anatomical	ADJ
fnp-3050	819	43	distribution	distribution	NOUN
fnp-3050	819	44	pattern	pattern	NOUN
fnp-3050	819	45	,	,	PUNCT
fnp-3050	819	46	evolutional	evolutional	ADJ
fnp-3050	819	47	features	feature	NOUN
fnp-3050	819	48	,	,	PUNCT
fnp-3050	819	49	pathogenetic	pathogenetic	ADJ
fnp-3050	819	50	and	and	CCONJ
fnp-3050	819	51	clinical	clinical	ADJ
fnp-3050	819	52	relevance	relevance	NOUN
fnp-3050	819	53	.	.	PUNCT
fnp-3050	820	1	curr	curr	PROPN
fnp-3050	820	2	alzheimer	alzheimer	PROPN
fnp-3050	820	3	res	res	PROPN
fnp-3050	820	4	13:1178	13:1178	NUM
fnp-3050	820	5	-	-	SYM
fnp-3050	820	6	1197	1197	NUM
fnp-3050	820	7	148	148	NUM
fnp-3050	820	8	.	.	PUNCT
fnp-3050	821	1	attems	attems	PROPN
fnp-3050	821	2	j	j	PROPN
fnp-3050	821	3	,	,	PUNCT
fnp-3050	821	4	quass	quass	PROPN
fnp-3050	821	5	m	m	PROPN
fnp-3050	821	6	,	,	PUNCT
fnp-3050	821	7	jellinger	jellinger	PROPN
fnp-3050	821	8	ka	ka	PROPN
fnp-3050	821	9	(	(	PUNCT
fnp-3050	821	10	2007	2007	NUM
fnp-3050	821	11	)	)	PUNCT
fnp-3050	821	12	tau	tau	PROPN
fnp-3050	821	13	and	and	CCONJ
fnp-3050	821	14	alpha	alpha	NOUN
fnp-3050	821	15	-	-	PUNCT
fnp-3050	821	16	synuclein	synuclein	NOUN
fnp-3050	821	17	brainstem	brainstem	NOUN
fnp-3050	821	18	pathology	pathology	NOUN
fnp-3050	821	19	in	in	ADP
fnp-3050	821	20	alzheimer	alzheimer	PROPN
fnp-3050	821	21	disease	disease	PROPN
fnp-3050	821	22	:	:	PUNCT
fnp-3050	821	23	relation	relation	NOUN
fnp-3050	821	24	with	with	ADP
fnp-3050	821	25	extrapyramidal	extrapyramidal	ADJ
fnp-3050	821	26	signs	sign	NOUN
fnp-3050	821	27	.	.	PUNCT
fnp-3050	822	1	acta	acta	PROPN
fnp-3050	822	2	neuropathol	neuropathol	PROPN
fnp-3050	822	3	113:53	113:53	NUM
fnp-3050	822	4	-	-	SYM
fnp-3050	822	5	62	62	NUM
fnp-3050	822	6	149	149	NUM
fnp-3050	822	7	.	.	PUNCT
fnp-3050	823	1	buchman	buchman	NOUN
fnp-3050	823	2	as	as	ADP
fnp-3050	823	3	,	,	PUNCT
fnp-3050	823	4	shulman	shulman	PROPN
fnp-3050	823	5	jm	jm	PROPN
fnp-3050	823	6	,	,	PUNCT
fnp-3050	823	7	nag	nag	VERB
fnp-3050	823	8	s	s	NOUN
fnp-3050	823	9	,	,	PUNCT
fnp-3050	823	10	leurgans	leurgans	PROPN
fnp-3050	823	11	se	se	PROPN
fnp-3050	823	12	,	,	PUNCT
fnp-3050	823	13	arnold	arnold	PROPN
fnp-3050	823	14	se	se	PROPN
fnp-3050	823	15	,	,	PUNCT
fnp-3050	823	16	morris	morris	PROPN
fnp-3050	823	17	mc	mc	PROPN
fnp-3050	823	18	,	,	PUNCT
fnp-3050	823	19	schneider	schneider	PROPN
fnp-3050	823	20	ja	ja	PROPN
fnp-3050	823	21	,	,	PUNCT
fnp-3050	823	22	bennett	bennett	PROPN
fnp-3050	823	23	da	da	PROPN
fnp-3050	823	24	(	(	PUNCT
fnp-3050	823	25	2012	2012	NUM
fnp-3050	823	26	)	)	PUNCT
fnp-3050	823	27	nigral	nigral	ADJ
fnp-3050	823	28	pathology	pathology	NOUN
fnp-3050	823	29	and	and	CCONJ
fnp-3050	823	30	parkinsonian	parkinsonian	ADJ
fnp-3050	823	31	signs	sign	NOUN
fnp-3050	823	32	in	in	ADP
fnp-3050	823	33	elders	elder	NOUN
fnp-3050	823	34	without	without	ADP
fnp-3050	823	35	parkinson	parkinson	NOUN
fnp-3050	823	36	disease	disease	NOUN
fnp-3050	823	37	.	.	PUNCT
fnp-3050	824	1	ann	ann	PROPN
fnp-3050	824	2	neurol	neurol	PROPN
fnp-3050	824	3	71:258	71:258	PROPN
fnp-3050	824	4	-	-	PUNCT
fnp-3050	824	5	266	266	NUM
fnp-3050	824	6	150	150	NUM
fnp-3050	824	7	.	.	PUNCT
fnp-3050	824	8	burns	burns	PROPN
fnp-3050	824	9	jm	jm	PROPN
fnp-3050	824	10	,	,	PUNCT
fnp-3050	824	11	galvin	galvin	PROPN
fnp-3050	824	12	je	je	PROPN
fnp-3050	824	13	,	,	PUNCT
fnp-3050	824	14	roe	roe	PROPN
fnp-3050	824	15	cm	cm	PROPN
fnp-3050	824	16	,	,	PUNCT
fnp-3050	824	17	morris	morris	PROPN
fnp-3050	824	18	jc	jc	PROPN
fnp-3050	824	19	,	,	PUNCT
fnp-3050	824	20	mckeel	mckeel	PROPN
fnp-3050	824	21	dw	dw	PROPN
fnp-3050	824	22	(	(	PUNCT
fnp-3050	824	23	2005	2005	NUM
fnp-3050	824	24	)	)	PUNCT
fnp-3050	824	25	the	the	DET
fnp-3050	824	26	pathology	pathology	NOUN
fnp-3050	824	27	of	of	ADP
fnp-3050	824	28	the	the	DET
fnp-3050	824	29	substantia	substantia	NOUN
fnp-3050	824	30	nigra	nigra	NOUN
fnp-3050	824	31	in	in	ADP
fnp-3050	824	32	alzheimer	alzheimer	PROPN
fnp-3050	824	33	disease	disease	NOUN
fnp-3050	824	34	with	with	ADP
fnp-3050	824	35	extrapyramidal	extrapyramidal	ADJ
fnp-3050	824	36	signs	sign	NOUN
fnp-3050	824	37	.	.	PUNCT
fnp-3050	825	1	neurology	neurology	NOUN
fnp-3050	825	2	64:1397	64:1397	NOUN
fnp-3050	825	3	-	-	PUNCT
fnp-3050	825	4	1403	1403	NUM
fnp-3050	825	5	151	151	NUM
fnp-3050	825	6	.	.	PUNCT
fnp-3050	826	1	kent	kent	PROPN
fnp-3050	826	2	sa	sa	PROPN
fnp-3050	826	3	,	,	PUNCT
fnp-3050	826	4	spires	spires	PROPN
fnp-3050	826	5	-	-	PUNCT
fnp-3050	826	6	jones	jones	PROPN
fnp-3050	826	7	tl	tl	PROPN
fnp-3050	826	8	,	,	PUNCT
fnp-3050	826	9	durrant	durrant	PROPN
fnp-3050	826	10	cs	cs	PROPN
fnp-3050	826	11	(	(	PUNCT
fnp-3050	826	12	2020	2020	NUM
fnp-3050	826	13	)	)	PUNCT
fnp-3050	826	14	the	the	DET
fnp-3050	826	15	physiological	physiological	ADJ
fnp-3050	826	16	roles	role	NOUN
fnp-3050	826	17	of	of	ADP
fnp-3050	826	18	tau	tau	PROPN
fnp-3050	826	19	and	and	CCONJ
fnp-3050	826	20	abeta	abeta	PROPN
fnp-3050	826	21	:	:	PUNCT
fnp-3050	826	22	implications	implication	NOUN
fnp-3050	826	23	for	for	ADP
fnp-3050	826	24	alzheimer	alzheimer	PROPN
fnp-3050	826	25	's	's	PART
fnp-3050	826	26	disease	disease	NOUN
fnp-3050	826	27	pathology	pathology	NOUN
fnp-3050	826	28	and	and	CCONJ
fnp-3050	826	29	therapeutics	therapeutic	NOUN
fnp-3050	826	30	.	.	PUNCT
fnp-3050	827	1	acta	acta	PROPN
fnp-3050	827	2	neuropathol	neuropathol	PROPN
fnp-3050	827	3	140:417	140:417	NUM
fnp-3050	827	4	-	-	SYM
fnp-3050	827	5	447	447	NUM
fnp-3050	827	6	152	152	NUM
fnp-3050	827	7	.	.	PUNCT
fnp-3050	828	1	kara	kara	PROPN
fnp-3050	828	2	e	e	PROPN
fnp-3050	828	3	,	,	PUNCT
fnp-3050	828	4	marks	marks	PROPN
fnp-3050	828	5	jd	jd	PROPN
fnp-3050	828	6	,	,	PUNCT
fnp-3050	828	7	aguzzi	aguzzi	VERB
fnp-3050	828	8	a	a	DET
fnp-3050	828	9	(	(	PUNCT
fnp-3050	828	10	2018	2018	NUM
fnp-3050	828	11	)	)	PUNCT
fnp-3050	828	12	toxic	toxic	ADJ
fnp-3050	828	13	protein	protein	NOUN
fnp-3050	828	14	spread	spread	VERB
fnp-3050	828	15	in	in	ADP
fnp-3050	828	16	neurodegeneration	neurodegeneration	NOUN
fnp-3050	828	17	:	:	PUNCT
fnp-3050	828	18	reality	reality	NOUN
fnp-3050	828	19	versus	versus	ADP
fnp-3050	828	20	fantasy	fantasy	NOUN
fnp-3050	828	21	.	.	PUNCT
fnp-3050	829	1	trends	trend	NOUN
fnp-3050	829	2	mol	mol	ADP
fnp-3050	829	3	med	med	ADJ
fnp-3050	829	4	24:1007	24:1007	NUM
fnp-3050	829	5	-	-	SYM
fnp-3050	829	6	1020	1020	NUM
fnp-3050	829	7	153	153	NUM
fnp-3050	829	8	.	.	PUNCT
fnp-3050	829	9	busche	busche	PROPN
fnp-3050	829	10	ma	ma	PROPN
fnp-3050	829	11	,	,	PUNCT
fnp-3050	829	12	hyman	hyman	PROPN
fnp-3050	829	13	bt	bt	PROPN
fnp-3050	829	14	(	(	PUNCT
fnp-3050	829	15	2020	2020	NUM
fnp-3050	829	16	)	)	PUNCT
fnp-3050	829	17	synergy	synergy	NOUN
fnp-3050	829	18	between	between	ADP
fnp-3050	829	19	amyloid	amyloid	NOUN
fnp-3050	829	20	-	-	PUNCT
fnp-3050	829	21	beta	beta	NOUN
fnp-3050	829	22	and	and	CCONJ
fnp-3050	829	23	tau	tau	PROPN
fnp-3050	829	24	in	in	ADP
fnp-3050	829	25	alzheimer	alzheimer	PROPN
fnp-3050	829	26	's	's	PART
fnp-3050	829	27	disease	disease	NOUN
fnp-3050	829	28	.	.	PUNCT
fnp-3050	830	1	nat	nat	PROPN
fnp-3050	830	2	neurosci	neurosci	PROPN
fnp-3050	830	3	23:1183	23:1183	NUM
fnp-3050	830	4	-	-	SYM
fnp-3050	830	5	1193	1193	NUM
fnp-3050	830	6	154	154	NUM
fnp-3050	830	7	.	.	PUNCT
fnp-3050	831	1	jucker	jucker	PROPN
fnp-3050	831	2	m	m	PROPN
fnp-3050	831	3	,	,	PUNCT
fnp-3050	831	4	walker	walker	PROPN
fnp-3050	831	5	lc	lc	PROPN
fnp-3050	831	6	(	(	PUNCT
fnp-3050	831	7	2018	2018	NUM
fnp-3050	831	8	)	)	PUNCT
fnp-3050	831	9	propagation	propagation	NOUN
fnp-3050	831	10	and	and	CCONJ
fnp-3050	831	11	spread	spread	VERB
fnp-3050	831	12	of	of	ADP
fnp-3050	831	13	pathogenic	pathogenic	ADJ
fnp-3050	831	14	protein	protein	NOUN
fnp-3050	831	15	assemblies	assembly	NOUN
fnp-3050	831	16	in	in	ADP
fnp-3050	831	17	neurodegenerative	neurodegenerative	ADJ
fnp-3050	831	18	diseases	disease	NOUN
fnp-3050	831	19	.	.	PUNCT
fnp-3050	832	1	nat	nat	PROPN
fnp-3050	832	2	neurosci	neurosci	PROPN
fnp-3050	832	3	21:1341	21:1341	PROPN
fnp-3050	832	4	-	-	SYM
fnp-3050	832	5	1349	1349	NUM
fnp-3050	832	6	155	155	NUM
fnp-3050	832	7	.	.	PUNCT
fnp-3050	833	1	thompson	thompson	PROPN
fnp-3050	833	2	tb	tb	PROPN
fnp-3050	833	3	,	,	PUNCT
fnp-3050	833	4	chaggar	chaggar	NOUN
fnp-3050	833	5	p	p	NOUN
fnp-3050	833	6	,	,	PUNCT
fnp-3050	833	7	kuhl	kuhl	PROPN
fnp-3050	833	8	e	e	PROPN
fnp-3050	833	9	,	,	PUNCT
fnp-3050	833	10	goriely	goriely	ADV
fnp-3050	833	11	a	a	DET
fnp-3050	833	12	(	(	PUNCT
fnp-3050	833	13	2020	2020	NUM
fnp-3050	833	14	)	)	PUNCT
fnp-3050	833	15	protein	protein	NOUN
fnp-3050	833	16	-	-	PUNCT
fnp-3050	833	17	protein	protein	NOUN
fnp-3050	833	18	interactions	interaction	NOUN
fnp-3050	833	19	in	in	ADP
fnp-3050	833	20	neurodegenerative	neurodegenerative	ADJ
fnp-3050	833	21	diseases	disease	NOUN
fnp-3050	833	22	:	:	PUNCT
fnp-3050	833	23	a	a	DET
fnp-3050	833	24	conspiracy	conspiracy	NOUN
fnp-3050	833	25	theory	theory	NOUN
fnp-3050	833	26	.	.	PUNCT
fnp-3050	834	1	plos	plos	PROPN
fnp-3050	834	2	comput	comput	PROPN
fnp-3050	834	3	biol	biol	PROPN
fnp-3050	834	4	16	16	NUM
fnp-3050	834	5	:	:	PUNCT
fnp-3050	834	6	e1008267	e1008267	PROPN
fnp-3050	834	7	156	156	NUM
fnp-3050	834	8	.	.	PUNCT
fnp-3050	835	1	bennett	bennett	PROPN
fnp-3050	835	2	re	re	PROPN
fnp-3050	835	3	,	,	PUNCT
fnp-3050	835	4	devos	devos	PROPN
fnp-3050	835	5	sl	sl	PROPN
fnp-3050	835	6	,	,	PUNCT
fnp-3050	835	7	dujardin	dujardin	PROPN
fnp-3050	835	8	s	s	PROPN
fnp-3050	835	9	,	,	PUNCT
fnp-3050	835	10	corjuc	corjuc	VERB
fnp-3050	835	11	b	b	NUM
fnp-3050	835	12	,	,	PUNCT
fnp-3050	835	13	gor	gor	PROPN
fnp-3050	835	14	r	r	PROPN
fnp-3050	835	15	,	,	PUNCT
fnp-3050	835	16	gonzalez	gonzalez	PROPN
fnp-3050	835	17	j	j	PROPN
fnp-3050	835	18	,	,	PUNCT
fnp-3050	835	19	roe	roe	PROPN
fnp-3050	835	20	ad	ad	NOUN
fnp-3050	835	21	,	,	PUNCT
fnp-3050	835	22	frosch	frosch	PROPN
fnp-3050	835	23	mp	mp	PROPN
fnp-3050	835	24	,	,	PUNCT
fnp-3050	835	25	pitstick	pitstick	NOUN
fnp-3050	835	26	r	r	NOUN
fnp-3050	835	27	,	,	PUNCT
fnp-3050	835	28	carlson	carlson	PROPN
fnp-3050	835	29	ga	ga	PROPN
fnp-3050	835	30	,	,	PUNCT
fnp-3050	835	31	hyman	hyman	PROPN
fnp-3050	835	32	bt	bt	PROPN
fnp-3050	835	33	(	(	PUNCT
fnp-3050	835	34	2017	2017	NUM
fnp-3050	835	35	)	)	PUNCT
fnp-3050	835	36	enhanced	enhance	VERB
fnp-3050	835	37	tau	tau	PROPN
fnp-3050	835	38	aggregation	aggregation	NOUN
fnp-3050	835	39	in	in	ADP
fnp-3050	835	40	the	the	DET
fnp-3050	835	41	presence	presence	NOUN
fnp-3050	835	42	of	of	ADP
fnp-3050	835	43	amyloid	amyloid	NOUN
fnp-3050	835	44	beta	beta	NOUN
fnp-3050	835	45	.	.	PUNCT
fnp-3050	836	1	am	be	AUX
fnp-3050	836	2	j	j	PROPN
fnp-3050	836	3	pathol	pathol	VERB
fnp-3050	836	4	187:1601	187:1601	PROPN
fnp-3050	836	5	-	-	SYM
fnp-3050	836	6	1612	1612	NUM
fnp-3050	836	7	157	157	NUM
fnp-3050	836	8	.	.	PUNCT
fnp-3050	837	1	pooler	pooler	PROPN
fnp-3050	837	2	am	am	PROPN
fnp-3050	837	3	,	,	PUNCT
fnp-3050	837	4	polydoro	polydoro	PROPN
fnp-3050	837	5	m	m	PROPN
fnp-3050	837	6	,	,	PUNCT
fnp-3050	837	7	maury	maury	PROPN
fnp-3050	837	8	ea	ea	PROPN
fnp-3050	837	9	,	,	PUNCT
fnp-3050	837	10	nicholls	nicholls	PROPN
fnp-3050	837	11	sb	sb	PROPN
fnp-3050	837	12	,	,	PUNCT
fnp-3050	837	13	reddy	reddy	PROPN
fnp-3050	837	14	sm	sm	PROPN
fnp-3050	837	15	,	,	PUNCT
fnp-3050	837	16	wegmann	wegmann	PROPN
fnp-3050	837	17	s	s	PROPN
fnp-3050	837	18	,	,	PUNCT
fnp-3050	837	19	william	william	PROPN
fnp-3050	837	20	c	c	PROPN
fnp-3050	837	21	,	,	PUNCT
fnp-3050	837	22	saqran	saqran	ADJ
fnp-3050	837	23	l	l	NOUN
fnp-3050	837	24	,	,	PUNCT
fnp-3050	837	25	cagsal	cagsal	NOUN
fnp-3050	837	26	-	-	PUNCT
fnp-3050	837	27	getkin	getkin	PROPN
fnp-3050	837	28	o	o	NOUN
fnp-3050	837	29	,	,	PUNCT
fnp-3050	837	30	pitstick	pitstick	NOUN
fnp-3050	837	31	r	r	PROPN
fnp-3050	837	32	,	,	PUNCT
fnp-3050	837	33	beier	beier	PROPN
fnp-3050	837	34	dr	dr	PROPN
fnp-3050	837	35	,	,	PUNCT
fnp-3050	837	36	carlson	carlson	PROPN
fnp-3050	837	37	ga	ga	PROPN
fnp-3050	837	38	,	,	PUNCT
fnp-3050	837	39	spires	spires	PROPN
fnp-3050	837	40	-	-	PUNCT
fnp-3050	837	41	jones	jones	PROPN
fnp-3050	837	42	tl	tl	PROPN
fnp-3050	837	43	,	,	PUNCT
fnp-3050	837	44	hyman	hyman	PROPN
fnp-3050	837	45	bt	bt	PROPN
fnp-3050	837	46	(	(	PUNCT
fnp-3050	837	47	2015	2015	NUM
fnp-3050	837	48	)	)	PUNCT
fnp-3050	837	49	amyloid	amyloid	NOUN
fnp-3050	837	50	accelerates	accelerate	VERB
fnp-3050	837	51	tau	tau	NOUN
fnp-3050	837	52	propagation	propagation	NOUN
fnp-3050	837	53	and	and	CCONJ
fnp-3050	837	54	toxicity	toxicity	NOUN
fnp-3050	837	55	in	in	ADP
fnp-3050	837	56	a	a	DET
fnp-3050	837	57	model	model	NOUN
fnp-3050	837	58	of	of	ADP
fnp-3050	837	59	early	early	ADJ
fnp-3050	837	60	alzheimer	alzheimer	PROPN
fnp-3050	837	61	's	's	PART
fnp-3050	837	62	disease	disease	NOUN
fnp-3050	837	63	.	.	PUNCT
fnp-3050	838	1	acta	acta	PROPN
fnp-3050	838	2	neuropathol	neuropathol	PROPN
fnp-3050	838	3	commun	commun	PROPN
fnp-3050	838	4	3:14	3:14	NUM
fnp-3050	838	5	158	158	NUM
fnp-3050	838	6	.	.	PUNCT
fnp-3050	839	1	cline	cline	PROPN
fnp-3050	839	2	en	en	PROPN
fnp-3050	839	3	,	,	PUNCT
fnp-3050	839	4	bicca	bicca	VERB
fnp-3050	839	5	ma	ma	PROPN
fnp-3050	839	6	,	,	PUNCT
fnp-3050	839	7	viola	viola	PROPN
fnp-3050	839	8	kl	kl	PROPN
fnp-3050	839	9	,	,	PUNCT
fnp-3050	839	10	klein	klein	PROPN
fnp-3050	839	11	wl	wl	PROPN
fnp-3050	839	12	(	(	PUNCT
fnp-3050	839	13	2018	2018	NUM
fnp-3050	839	14	)	)	PUNCT
fnp-3050	839	15	the	the	DET
fnp-3050	839	16	amyloid	amyloid	NOUN
fnp-3050	839	17	-	-	PUNCT
fnp-3050	839	18	ß	ß	NOUN
fnp-3050	839	19	oligomer	oligomer	ADJ
fnp-3050	839	20	hypothesis	hypothesis	NOUN
fnp-3050	839	21	:	:	PUNCT
fnp-3050	839	22	beginning	begin	VERB
fnp-3050	839	23	of	of	ADP
fnp-3050	839	24	the	the	DET
fnp-3050	839	25	third	third	ADJ
fnp-3050	839	26	decade	decade	NOUN
fnp-3050	839	27	.	.	PUNCT
fnp-3050	840	1	j	j	PROPN
fnp-3050	840	2	alzheimers	alzheimers	PROPN
fnp-3050	840	3	dis	dis	PROPN
fnp-3050	840	4	64	64	NUM
fnp-3050	840	5	:	:	PUNCT
fnp-3050	840	6	s567	s567	NUM
fnp-3050	840	7	-	-	SYM
fnp-3050	840	8	s610	s610	PROPN
fnp-3050	840	9	159	159	NUM
fnp-3050	840	10	.	.	PUNCT
fnp-3050	841	1	iadanza	iadanza	NOUN
fnp-3050	841	2	mg	mg	PROPN
fnp-3050	841	3	,	,	PUNCT
fnp-3050	841	4	jackson	jackson	PROPN
fnp-3050	841	5	mp	mp	PROPN
fnp-3050	841	6	,	,	PUNCT
fnp-3050	841	7	hewitt	hewitt	PROPN
fnp-3050	841	8	ew	ew	PROPN
fnp-3050	841	9	,	,	PUNCT
fnp-3050	841	10	ranson	ranson	PROPN
fnp-3050	841	11	na	na	PROPN
fnp-3050	841	12	,	,	PUNCT
fnp-3050	841	13	radford	radford	PROPN
fnp-3050	841	14	se	se	PROPN
fnp-3050	841	15	(	(	PUNCT
fnp-3050	841	16	2018	2018	NUM
fnp-3050	841	17	)	)	PUNCT
fnp-3050	841	18	a	a	DET
fnp-3050	841	19	new	new	ADJ
fnp-3050	841	20	era	era	NOUN
fnp-3050	841	21	for	for	ADP
fnp-3050	841	22	understanding	understand	VERB
fnp-3050	841	23	amyloid	amyloid	NOUN
fnp-3050	841	24	structures	structure	NOUN
fnp-3050	841	25	and	and	CCONJ
fnp-3050	841	26	disease	disease	NOUN
fnp-3050	841	27	.	.	PUNCT
fnp-3050	842	1	nat	nat	PROPN
fnp-3050	842	2	rev	rev	VERB
fnp-3050	842	3	mol	mol	ADP
fnp-3050	842	4	cell	cell	NOUN
fnp-3050	842	5	biol	biol	NOUN
fnp-3050	842	6	19:755	19:755	NUM
fnp-3050	842	7	-	-	SYM
fnp-3050	842	8	773	773	NUM
fnp-3050	842	9	160	160	NUM
fnp-3050	842	10	.	.	PUNCT
fnp-3050	843	1	okamura	okamura	PRON
fnp-3050	843	2	n	n	SYM
fnp-3050	843	3	,	,	PUNCT
fnp-3050	843	4	harada	harada	PROPN
fnp-3050	843	5	r	r	PROPN
fnp-3050	843	6	,	,	PUNCT
fnp-3050	843	7	furumoto	furumoto	PROPN
fnp-3050	843	8	s	s	PROPN
fnp-3050	843	9	,	,	PUNCT
fnp-3050	843	10	arai	arai	PROPN
fnp-3050	843	11	h	h	NOUN
fnp-3050	843	12	,	,	PUNCT
fnp-3050	843	13	yanai	yanai	PROPN
fnp-3050	843	14	k	k	NOUN
fnp-3050	843	15	,	,	PUNCT
fnp-3050	843	16	kudo	kudo	PROPN
fnp-3050	843	17	y	y	PROPN
fnp-3050	843	18	(	(	PUNCT
fnp-3050	843	19	2014	2014	NUM
fnp-3050	843	20	)	)	PUNCT
fnp-3050	844	1	tau	tau	PROPN
fnp-3050	844	2	pet	pet	ADJ
fnp-3050	844	3	imaging	imaging	NOUN
fnp-3050	844	4	in	in	ADP
fnp-3050	844	5	alzheimer	alzheimer	PROPN
fnp-3050	844	6	's	's	PART
fnp-3050	844	7	disease	disease	NOUN
fnp-3050	844	8	.	.	PUNCT
fnp-3050	845	1	curr	curr	PROPN
fnp-3050	845	2	neurol	neurol	PROPN
fnp-3050	845	3	neurosci	neurosci	PROPN
fnp-3050	845	4	rep	rep	PROPN
fnp-3050	845	5	14:500	14:500	NUM
fnp-3050	845	6	161	161	NUM
fnp-3050	845	7	.	.	PUNCT
fnp-3050	846	1	keene	keene	PROPN
fnp-3050	846	2	cd	cd	PROPN
fnp-3050	846	3	,	,	PUNCT
fnp-3050	846	4	wilson	wilson	PROPN
fnp-3050	846	5	am	am	PROPN
fnp-3050	846	6	,	,	PUNCT
fnp-3050	846	7	kilgore	kilgore	PROPN
fnp-3050	846	8	md	md	PROPN
fnp-3050	846	9	,	,	PUNCT
fnp-3050	846	10	bruner	bruner	PROPN
fnp-3050	846	11	lt	lt	PROPN
fnp-3050	846	12	,	,	PUNCT
fnp-3050	846	13	postupna	postupna	VERB
fnp-3050	846	14	no	no	ADP
fnp-3050	846	15	,	,	PUNCT
fnp-3050	846	16	darvas	darvas	PROPN
fnp-3050	846	17	m	m	PROPN
fnp-3050	846	18	(	(	PUNCT
fnp-3050	846	19	2019	2019	NUM
fnp-3050	846	20	)	)	PUNCT
fnp-3050	846	21	luminex	luminex	NOUN
fnp-3050	846	22	-	-	PUNCT
fnp-3050	846	23	based	base	VERB
fnp-3050	846	24	quantification	quantification	NOUN
fnp-3050	846	25	of	of	ADP
fnp-3050	846	26	alzheimer	alzheimer	PROPN
fnp-3050	846	27	's	's	PART
fnp-3050	846	28	disease	disease	NOUN
fnp-3050	846	29	neuropathologic	neuropathologic	NOUN
fnp-3050	846	30	change	change	NOUN
fnp-3050	846	31	in	in	ADP
fnp-3050	846	32	formalin	formalin	NOUN
fnp-3050	846	33	-	-	PUNCT
fnp-3050	846	34	fixed	fix	VERB
fnp-3050	846	35	post	post	ADJ
fnp-3050	846	36	-	-	ADJ
fnp-3050	846	37	mortem	mortem	ADJ
fnp-3050	846	38	human	human	ADJ
fnp-3050	846	39	brain	brain	NOUN
fnp-3050	846	40	tissue	tissue	NOUN
fnp-3050	846	41	.	.	PUNCT
fnp-3050	847	1	lab	lab	NOUN
fnp-3050	847	2	invest	invest	VERB
fnp-3050	847	3	99:1056	99:1056	NOUN
fnp-3050	847	4	-	-	ADJ
fnp-3050	847	5	1067	1067	NUM
fnp-3050	847	6	162	162	NUM
fnp-3050	847	7	.	.	PUNCT
fnp-3050	848	1	walsh	walsh	PROPN
fnp-3050	848	2	dm	dm	PROPN
fnp-3050	848	3	,	,	PUNCT
fnp-3050	848	4	selkoe	selkoe	ADJ
fnp-3050	848	5	dj	dj	X
fnp-3050	848	6	(	(	PUNCT
fnp-3050	848	7	2020	2020	NUM
fnp-3050	848	8	)	)	PUNCT
fnp-3050	848	9	amyloid	amyloid	NOUN
fnp-3050	848	10	beta	beta	NOUN
fnp-3050	848	11	-	-	PUNCT
fnp-3050	848	12	protein	protein	NOUN
fnp-3050	848	13	and	and	CCONJ
fnp-3050	848	14	beyond	beyond	ADP
fnp-3050	848	15	:	:	PUNCT
fnp-3050	848	16	the	the	DET
fnp-3050	848	17	path	path	NOUN
fnp-3050	848	18	forward	forward	ADV
fnp-3050	848	19	in	in	ADP
fnp-3050	848	20	alzheimer	alzheimer	PROPN
fnp-3050	848	21	's	's	PART
fnp-3050	848	22	disease	disease	NOUN
fnp-3050	848	23	.	.	PUNCT
fnp-3050	849	1	curr	curr	PROPN
fnp-3050	849	2	opin	opin	NOUN
fnp-3050	849	3	neurobiol	neurobiol	PROPN
fnp-3050	849	4	61:116	61:116	PROPN
fnp-3050	849	5	-	-	SYM
fnp-3050	849	6	124	124	NUM
fnp-3050	849	7	163	163	NUM
fnp-3050	849	8	.	.	PUNCT
fnp-3050	850	1	selkoe	selkoe	ADJ
fnp-3050	850	2	dj	dj	NOUN
fnp-3050	850	3	,	,	PUNCT
fnp-3050	850	4	hardy	hardy	ADJ
fnp-3050	850	5	j	j	PROPN
fnp-3050	850	6	(	(	PUNCT
fnp-3050	850	7	2016	2016	NUM
fnp-3050	850	8	)	)	PUNCT
fnp-3050	850	9	the	the	DET
fnp-3050	850	10	amyloid	amyloid	NOUN
fnp-3050	850	11	hypothesis	hypothesis	NOUN
fnp-3050	850	12	of	of	ADP
fnp-3050	850	13	alzheimer	alzheimer	PROPN
fnp-3050	850	14	's	's	PART
fnp-3050	850	15	disease	disease	NOUN
fnp-3050	850	16	at	at	ADP
fnp-3050	850	17	25	25	NUM
fnp-3050	850	18	years	year	NOUN
fnp-3050	850	19	.	.	PUNCT
fnp-3050	851	1	embo	embo	NOUN
fnp-3050	851	2	mol	mol	ADP
fnp-3050	851	3	med	med	PROPN
fnp-3050	851	4	8:595	8:595	PROPN
fnp-3050	851	5	-	-	PROPN
fnp-3050	851	6	608	608	NUM
fnp-3050	851	7	164	164	NUM
fnp-3050	851	8	.	.	PUNCT
fnp-3050	852	1	viola	viola	PROPN
fnp-3050	852	2	kl	kl	PROPN
fnp-3050	852	3	,	,	PUNCT
fnp-3050	852	4	klein	klein	PROPN
fnp-3050	852	5	wl	wl	PROPN
fnp-3050	852	6	(	(	PUNCT
fnp-3050	852	7	2015	2015	NUM
fnp-3050	852	8	)	)	PUNCT
fnp-3050	852	9	amyloid	amyloid	NOUN
fnp-3050	852	10	beta	beta	ADJ
fnp-3050	852	11	oligomers	oligomer	NOUN
fnp-3050	852	12	in	in	ADP
fnp-3050	852	13	alzheimer	alzheimer	PROPN
fnp-3050	852	14	's	's	PART
fnp-3050	852	15	disease	disease	NOUN
fnp-3050	852	16	pathogenesis	pathogenesis	NOUN
fnp-3050	852	17	,	,	PUNCT
fnp-3050	852	18	treatment	treatment	NOUN
fnp-3050	852	19	,	,	PUNCT
fnp-3050	852	20	and	and	CCONJ
fnp-3050	852	21	diagnosis	diagnosis	NOUN
fnp-3050	852	22	.	.	PUNCT
fnp-3050	853	1	acta	acta	PROPN
fnp-3050	853	2	neuropathol	neuropathol	PROPN
fnp-3050	853	3	129:183	129:183	NUM
fnp-3050	853	4	-	-	SYM
fnp-3050	853	5	206	206	NUM
fnp-3050	853	6	165	165	NUM
fnp-3050	853	7	.	.	PUNCT
fnp-3050	854	1	gomes	gomes	PROPN
fnp-3050	854	2	la	la	PROPN
fnp-3050	854	3	,	,	PUNCT
fnp-3050	854	4	hipp	hipp	PROPN
fnp-3050	854	5	sa	sa	PROPN
fnp-3050	854	6	,	,	PUNCT
fnp-3050	854	7	rijal	rijal	VERB
fnp-3050	854	8	upadhaya	upadhaya	NOUN
fnp-3050	854	9	a	a	PRON
fnp-3050	854	10	,	,	PUNCT
fnp-3050	854	11	balakrishnan	balakrishnan	PROPN
fnp-3050	854	12	k	k	NOUN
fnp-3050	854	13	,	,	PUNCT
fnp-3050	854	14	ospitalieri	ospitalieri	PROPN
fnp-3050	854	15	s	s	PROPN
fnp-3050	854	16	,	,	PUNCT
fnp-3050	854	17	koper	koper	PROPN
fnp-3050	854	18	mj	mj	PROPN
fnp-3050	854	19	,	,	PUNCT
fnp-3050	854	20	largo	largo	PROPN
fnp-3050	854	21	-	-	PUNCT
fnp-3050	854	22	barrientos	barrientos	PROPN
fnp-3050	854	23	p	p	NOUN
fnp-3050	854	24	,	,	PUNCT
fnp-3050	854	25	uytterhoeven	uytterhoeven	PROPN
fnp-3050	854	26	v	v	ADP
fnp-3050	854	27	,	,	PUNCT
fnp-3050	854	28	reichwald	reichwald	PROPN
fnp-3050	854	29	j	j	PROPN
fnp-3050	854	30	,	,	PUNCT
fnp-3050	854	31	rabe	rabe	PROPN
fnp-3050	854	32	s	s	PROPN
fnp-3050	854	33	,	,	PUNCT
fnp-3050	854	34	vandenberghe	vandenberghe	ADJ
fnp-3050	854	35	r	r	PROPN
fnp-3050	854	36	,	,	PUNCT
fnp-3050	854	37	von	von	PROPN
fnp-3050	854	38	arnim	arnim	PROPN
fnp-3050	854	39	caf	caf	PROPN
fnp-3050	854	40	,	,	PUNCT
fnp-3050	854	41	tousseyn	tousseyn	NOUN
fnp-3050	854	42	t	t	PROPN
fnp-3050	854	43	,	,	PUNCT
fnp-3050	854	44	feederle	feederle	ADJ
fnp-3050	854	45	r	r	NOUN
fnp-3050	854	46	,	,	PUNCT
fnp-3050	854	47	giudici	giudici	NOUN
fnp-3050	854	48	c	c	X
fnp-3050	854	49	,	,	PUNCT
fnp-3050	854	50	willem	willem	PROPN
fnp-3050	854	51	m	m	PROPN
fnp-3050	854	52	,	,	PUNCT
fnp-3050	854	53	staufenbiel	staufenbiel	PROPN
fnp-3050	854	54	m	m	PROPN
fnp-3050	854	55	,	,	PUNCT
fnp-3050	854	56	thal	thal	PROPN
fnp-3050	854	57	dr	dr	PROPN
fnp-3050	854	58	(	(	PUNCT
fnp-3050	854	59	2019	2019	NUM
fnp-3050	854	60	)	)	PUNCT
fnp-3050	854	61	abeta	abeta	NOUN
fnp-3050	854	62	-	-	PUNCT
fnp-3050	854	63	induced	induce	VERB
fnp-3050	854	64	acceleration	acceleration	NOUN
fnp-3050	854	65	of	of	ADP
fnp-3050	854	66	alzheimer	alzheimer	PROPN
fnp-3050	854	67	-	-	PUNCT
fnp-3050	854	68	related	relate	VERB
fnp-3050	854	69	tau	tau	NOUN
fnp-3050	854	70	-	-	PUNCT
fnp-3050	854	71	pathology	pathology	NOUN
fnp-3050	854	72	spreading	spread	VERB
fnp-3050	854	73	and	and	CCONJ
fnp-3050	854	74	its	its	PRON
fnp-3050	854	75	association	association	NOUN
fnp-3050	854	76	with	with	ADP
fnp-3050	854	77	prion	prion	NOUN
fnp-3050	854	78	protein	protein	NOUN
fnp-3050	854	79	.	.	PUNCT
fnp-3050	855	1	acta	acta	PROPN
fnp-3050	855	2	neuropathol	neuropathol	PROPN
fnp-3050	855	3	138:913	138:913	PROPN
fnp-3050	855	4	-	-	SYM
fnp-3050	855	5	941	941	NUM
fnp-3050	855	6	166	166	NUM
fnp-3050	855	7	.	.	PUNCT
fnp-3050	856	1	vergara	vergara	PROPN
fnp-3050	856	2	c	c	PROPN
fnp-3050	856	3	,	,	PUNCT
fnp-3050	856	4	houben	houben	PROPN
fnp-3050	856	5	s	s	PART
fnp-3050	856	6	,	,	PUNCT
fnp-3050	856	7	suain	suain	NOUN
fnp-3050	856	8	v	v	NOUN
fnp-3050	856	9	,	,	PUNCT
fnp-3050	856	10	yilmaz	yilmaz	PROPN
fnp-3050	856	11	z	z	PROPN
fnp-3050	856	12	,	,	PUNCT
fnp-3050	856	13	de	de	PROPN
fnp-3050	856	14	decker	decker	PROPN
fnp-3050	856	15	r	r	PROPN
fnp-3050	856	16	,	,	PUNCT
fnp-3050	856	17	vanden	vanden	PROPN
fnp-3050	856	18	dries	dry	NOUN
fnp-3050	856	19	v	v	NOUN
fnp-3050	856	20	,	,	PUNCT
fnp-3050	856	21	boom	boom	NOUN
fnp-3050	856	22	a	a	NOUN
fnp-3050	856	23	,	,	PUNCT
fnp-3050	856	24	mansour	mansour	PROPN
fnp-3050	856	25	s	s	PROPN
fnp-3050	856	26	,	,	PUNCT
fnp-3050	856	27	leroy	leroy	PROPN
fnp-3050	856	28	k	k	PROPN
fnp-3050	856	29	,	,	PUNCT
fnp-3050	856	30	ando	ando	PROPN
fnp-3050	856	31	k	k	PROPN
fnp-3050	856	32	,	,	PUNCT
fnp-3050	856	33	brion	brion	PROPN
fnp-3050	856	34	jp	jp	PROPN
fnp-3050	856	35	(	(	PUNCT
fnp-3050	856	36	2019	2019	NUM
fnp-3050	856	37	)	)	PUNCT
fnp-3050	856	38	amyloid	amyloid	NOUN
fnp-3050	856	39	-	-	PUNCT
fnp-3050	856	40	beta	beta	NOUN
fnp-3050	856	41	pathology	pathology	NOUN
fnp-3050	856	42	enhances	enhance	VERB
fnp-3050	856	43	pathological	pathological	ADJ
fnp-3050	856	44	fibrillary	fibrillary	ADJ
fnp-3050	856	45	tau	tau	NOUN
fnp-3050	856	46	seeding	seeding	NOUN
fnp-3050	856	47	induced	induce	VERB
fnp-3050	856	48	by	by	ADP
fnp-3050	856	49	alzheimer	alzheimer	PROPN
fnp-3050	856	50	phf	phf	PROPN
fnp-3050	856	51	in	in	ADP
fnp-3050	856	52	vivo	vivo	NOUN
fnp-3050	856	53	.	.	PUNCT
fnp-3050	857	1	acta	acta	PROPN
fnp-3050	857	2	neuropathol	neuropathol	PROPN
fnp-3050	857	3	137:397	137:397	PROPN
fnp-3050	857	4	-	-	SYM
fnp-3050	857	5	412	412	NUM
fnp-3050	857	6	167	167	NUM
fnp-3050	857	7	.	.	PUNCT
fnp-3050	858	1	wu	wu	PROPN
fnp-3050	858	2	hy	hy	PROPN
fnp-3050	858	3	,	,	PUNCT
fnp-3050	858	4	kuo	kuo	PROPN
fnp-3050	858	5	pc	pc	PROPN
fnp-3050	858	6	,	,	PUNCT
fnp-3050	858	7	wang	wang	PROPN
fnp-3050	858	8	yt	yt	PROPN
fnp-3050	858	9	,	,	PUNCT
fnp-3050	858	10	lin	lin	PROPN
fnp-3050	858	11	ht	ht	PROPN
fnp-3050	858	12	,	,	PUNCT
fnp-3050	858	13	roe	roe	PROPN
fnp-3050	858	14	ad	ad	NOUN
fnp-3050	858	15	,	,	PUNCT
fnp-3050	858	16	wang	wang	PROPN
fnp-3050	858	17	by	by	ADP
fnp-3050	858	18	,	,	PUNCT
fnp-3050	858	19	han	han	PROPN
fnp-3050	858	20	cl	cl	PROPN
fnp-3050	858	21	,	,	PUNCT
fnp-3050	858	22	hyman	hyman	PROPN
fnp-3050	858	23	bt	bt	PROPN
fnp-3050	858	24	,	,	PUNCT
fnp-3050	858	25	chen	chen	PROPN
fnp-3050	858	26	yj	yj	PROPN
fnp-3050	858	27	,	,	PUNCT
fnp-3050	858	28	tai	tai	PROPN
fnp-3050	858	29	hc	hc	PROPN
fnp-3050	858	30	(	(	PUNCT
fnp-3050	858	31	2018	2018	NUM
fnp-3050	858	32	)	)	PUNCT
fnp-3050	858	33	beta	beta	NOUN
fnp-3050	858	34	-	-	PUNCT
fnp-3050	858	35	amyloid	amyloid	NOUN
fnp-3050	858	36	induces	induce	VERB
fnp-3050	858	37	pathology	pathology	NOUN
fnp-3050	858	38	-	-	PUNCT
fnp-3050	858	39	related	relate	VERB
fnp-3050	858	40	patterns	pattern	NOUN
fnp-3050	858	41	of	of	ADP
fnp-3050	858	42	tau	tau	PROPN
fnp-3050	858	43	hyperphosphorylation	hyperphosphorylation	NOUN
fnp-3050	858	44	at	at	ADP
fnp-3050	858	45	synaptic	synaptic	ADJ
fnp-3050	858	46	terminals	terminal	NOUN
fnp-3050	858	47	.	.	PUNCT
fnp-3050	859	1	j	j	PROPN
fnp-3050	859	2	neuropathol	neuropathol	PROPN
fnp-3050	859	3	exp	exp	PROPN
fnp-3050	859	4	neurol	neurol	PROPN
fnp-3050	859	5	77:814	77:814	PROPN
fnp-3050	859	6	-	-	SYM
fnp-3050	859	7	826	826	NUM
fnp-3050	859	8	168	168	NUM
fnp-3050	859	9	.	.	PUNCT
fnp-3050	860	1	he	he	PRON
fnp-3050	860	2	z	z	X
fnp-3050	860	3	,	,	PUNCT
fnp-3050	860	4	guo	guo	PROPN
fnp-3050	860	5	jl	jl	PROPN
fnp-3050	860	6	,	,	PUNCT
fnp-3050	860	7	mcbride	mcbride	PROPN
fnp-3050	860	8	jd	jd	PROPN
fnp-3050	860	9	,	,	PUNCT
fnp-3050	860	10	narasimhan	narasimhan	PROPN
fnp-3050	860	11	s	s	PROPN
fnp-3050	860	12	,	,	PUNCT
fnp-3050	860	13	kim	kim	PROPN
fnp-3050	860	14	h	h	PROPN
fnp-3050	860	15	,	,	PUNCT
fnp-3050	860	16	changolkar	changolkar	PROPN
fnp-3050	860	17	l	l	PROPN
fnp-3050	860	18	,	,	PUNCT
fnp-3050	860	19	zhang	zhang	PROPN
fnp-3050	860	20	b	b	PROPN
fnp-3050	860	21	,	,	PUNCT
fnp-3050	860	22	gathagan	gathagan	PROPN
fnp-3050	860	23	rj	rj	PROPN
fnp-3050	860	24	,	,	PUNCT
fnp-3050	860	25	yue	yue	PROPN
fnp-3050	860	26	c	c	PROPN
fnp-3050	860	27	,	,	PUNCT
fnp-3050	860	28	dengler	dengler	NOUN
fnp-3050	860	29	c	c	PROPN
fnp-3050	860	30	,	,	PUNCT
fnp-3050	860	31	stieber	stieber	VERB
fnp-3050	860	32	a	a	PRON
fnp-3050	860	33	,	,	PUNCT
fnp-3050	860	34	nitla	nitla	PROPN
fnp-3050	860	35	m	m	PROPN
fnp-3050	860	36	,	,	PUNCT
fnp-3050	860	37	coulter	coulter	PROPN
fnp-3050	860	38	da	da	PROPN
fnp-3050	860	39	,	,	PUNCT
fnp-3050	860	40	abel	abel	PROPN
fnp-3050	860	41	t	t	PROPN
fnp-3050	860	42	,	,	PUNCT
fnp-3050	860	43	brunden	brunden	ADJ
fnp-3050	860	44	kr	kr	PROPN
fnp-3050	860	45	,	,	PUNCT
fnp-3050	860	46	trojanowski	trojanowski	PROPN
fnp-3050	860	47	jq	jq	PROPN
fnp-3050	860	48	,	,	PUNCT
fnp-3050	860	49	lee	lee	PROPN
fnp-3050	860	50	vm	vm	PROPN
fnp-3050	860	51	(	(	PUNCT
fnp-3050	860	52	2018	2018	NUM
fnp-3050	860	53	)	)	PUNCT
fnp-3050	860	54	amyloid	amyloid	NOUN
fnp-3050	860	55	-	-	PUNCT
fnp-3050	860	56	ß	ß	NOUN
fnp-3050	860	57	plaques	plaque	NOUN
fnp-3050	860	58	enhance	enhance	VERB
fnp-3050	860	59	alzheimer	alzheimer	PROPN
fnp-3050	860	60	's	's	PART
fnp-3050	860	61	brain	brain	NOUN
fnp-3050	860	62	tau	tau	NOUN
fnp-3050	860	63	-	-	PUNCT
fnp-3050	860	64	seeded	seed	VERB
fnp-3050	860	65	pathologies	pathology	NOUN
fnp-3050	860	66	by	by	ADP
fnp-3050	860	67	facilitating	facilitate	VERB
fnp-3050	860	68	neuritic	neuritic	ADJ
fnp-3050	860	69	plaque	plaque	NOUN
fnp-3050	860	70	tau	tau	PROPN
fnp-3050	860	71	aggregation	aggregation	NOUN
fnp-3050	860	72	.	.	PUNCT
fnp-3050	861	1	nat	nat	PROPN
fnp-3050	861	2	med	me	VERB
fnp-3050	861	3	24:29	24:29	NUM
fnp-3050	861	4	-	-	SYM
fnp-3050	861	5	38	38	NUM
fnp-3050	861	6	169	169	NUM
fnp-3050	861	7	.	.	PUNCT
fnp-3050	862	1	de	de	X
fnp-3050	862	2	felice	felice	PROPN
fnp-3050	862	3	fg	fg	PROPN
fnp-3050	862	4	,	,	PUNCT
fnp-3050	862	5	wu	wu	PROPN
fnp-3050	862	6	d	d	PROPN
fnp-3050	862	7	,	,	PUNCT
fnp-3050	862	8	lambert	lambert	PROPN
fnp-3050	862	9	mp	mp	PROPN
fnp-3050	862	10	,	,	PUNCT
fnp-3050	862	11	fernandez	fernandez	PROPN
fnp-3050	862	12	sj	sj	PROPN
fnp-3050	862	13	,	,	PUNCT
fnp-3050	862	14	velasco	velasco	PROPN
fnp-3050	862	15	pt	pt	PROPN
fnp-3050	862	16	,	,	PUNCT
fnp-3050	862	17	lacor	lacor	PROPN
fnp-3050	862	18	pn	pn	PROPN
fnp-3050	862	19	,	,	PUNCT
fnp-3050	862	20	bigio	bigio	NOUN
fnp-3050	862	21	eh	eh	INTJ
fnp-3050	862	22	,	,	PUNCT
fnp-3050	862	23	jerecic	jerecic	PROPN
fnp-3050	862	24	j	j	PROPN
fnp-3050	862	25	,	,	PUNCT
fnp-3050	862	26	acton	acton	PROPN
fnp-3050	862	27	pj	pj	PROPN
fnp-3050	862	28	,	,	PUNCT
fnp-3050	862	29	shughrue	shughrue	PROPN
fnp-3050	862	30	pj	pj	PROPN
fnp-3050	862	31	,	,	PUNCT
fnp-3050	862	32	chen	chen	PROPN
fnp-3050	862	33	-	-	PUNCT
fnp-3050	862	34	dodson	dodson	PROPN
fnp-3050	862	35	e	e	PROPN
fnp-3050	862	36	,	,	PUNCT
fnp-3050	862	37	kinney	kinney	PROPN
fnp-3050	862	38	gg	gg	PROPN
fnp-3050	862	39	,	,	PUNCT
fnp-3050	862	40	klein	klein	PROPN
fnp-3050	862	41	wl	wl	PROPN
fnp-3050	862	42	(	(	PUNCT
fnp-3050	862	43	2008	2008	NUM
fnp-3050	862	44	)	)	PUNCT
fnp-3050	862	45	alzheimer	alzheimer	PROPN
fnp-3050	862	46	's	's	PART
fnp-3050	862	47	disease	disease	NOUN
fnp-3050	862	48	-	-	PUNCT
fnp-3050	862	49	type	type	NOUN
fnp-3050	862	50	neuronal	neuronal	ADJ
fnp-3050	862	51	tau	tau	PROPN
fnp-3050	862	52	hyperphosphorylation	hyperphosphorylation	NOUN
fnp-3050	862	53	induced	induce	VERB
fnp-3050	862	54	by	by	ADP
fnp-3050	862	55	a	a	DET
fnp-3050	862	56	beta	beta	ADJ
fnp-3050	862	57	oligomers	oligomer	NOUN
fnp-3050	862	58	.	.	PUNCT
fnp-3050	863	1	neurobiol	neurobiol	PROPN
fnp-3050	863	2	aging	age	VERB
fnp-3050	863	3	29:1334	29:1334	PROPN
fnp-3050	863	4	-	-	SYM
fnp-3050	863	5	1347	1347	NUM
fnp-3050	863	6	170	170	NUM
fnp-3050	863	7	.	.	PUNCT
fnp-3050	864	1	shin	shin	PROPN
fnp-3050	864	2	ws	ws	PROPN
fnp-3050	864	3	,	,	PUNCT
fnp-3050	864	4	di	di	PROPN
fnp-3050	864	5	j	j	PROPN
fnp-3050	864	6	,	,	PUNCT
fnp-3050	864	7	cao	cao	PROPN
fnp-3050	864	8	q	q	PROPN
fnp-3050	864	9	,	,	PUNCT
fnp-3050	864	10	li	li	PROPN
fnp-3050	864	11	b	b	PROPN
fnp-3050	864	12	,	,	PUNCT
fnp-3050	864	13	seidler	seidler	NOUN
fnp-3050	864	14	pm	pm	NOUN
fnp-3050	864	15	,	,	PUNCT
fnp-3050	864	16	murray	murray	PROPN
fnp-3050	864	17	ka	ka	PROPN
fnp-3050	864	18	,	,	PUNCT
fnp-3050	864	19	bitan	bitan	PROPN
fnp-3050	864	20	g	g	PROPN
fnp-3050	864	21	,	,	PUNCT
fnp-3050	864	22	jiang	jiang	PROPN
fnp-3050	864	23	l	l	PROPN
fnp-3050	864	24	(	(	PUNCT
fnp-3050	864	25	2019	2019	NUM
fnp-3050	864	26	)	)	PUNCT
fnp-3050	864	27	amyloid	amyloid	NOUN
fnp-3050	864	28	beta	beta	NOUN
fnp-3050	864	29	-	-	PUNCT
fnp-3050	864	30	protein	protein	NOUN
fnp-3050	864	31	oligomers	oligomer	NOUN
fnp-3050	864	32	promote	promote	VERB
fnp-3050	864	33	the	the	DET
fnp-3050	864	34	uptake	uptake	NOUN
fnp-3050	864	35	of	of	ADP
fnp-3050	864	36	tau	tau	PROPN
fnp-3050	864	37	fibril	fibril	ADJ
fnp-3050	864	38	seeds	seed	NOUN
fnp-3050	864	39	potentiating	potentiate	VERB
fnp-3050	864	40	intracellular	intracellular	ADJ
fnp-3050	864	41	tau	tau	NOUN
fnp-3050	864	42	aggregation	aggregation	NOUN
fnp-3050	864	43	.	.	PUNCT
fnp-3050	865	1	alzheimers	alzheimer	NOUN
fnp-3050	865	2	res	re	VERB
fnp-3050	865	3	ther	ther	ADV
fnp-3050	865	4	11:86	11:86	NUM
fnp-3050	865	5	171	171	NUM
fnp-3050	865	6	.	.	PUNCT
fnp-3050	866	1	welikovitch	welikovitch	PROPN
fnp-3050	866	2	la	la	PROPN
fnp-3050	866	3	,	,	PUNCT
fnp-3050	866	4	do	do	VERB
fnp-3050	866	5	carmo	carmo	PROPN
fnp-3050	866	6	s	s	PROPN
fnp-3050	866	7	,	,	PUNCT
fnp-3050	866	8	maglóczky	maglóczky	ADJ
fnp-3050	866	9	z	z	NOUN
fnp-3050	866	10	,	,	PUNCT
fnp-3050	866	11	szocsics	szocsic	NOUN
fnp-3050	866	12	p	p	NOUN
fnp-3050	866	13	,	,	PUNCT
fnp-3050	866	14	loke	loke	ADV
fnp-3050	866	15	j	j	PROPN
fnp-3050	866	16	,	,	PUNCT
fnp-3050	866	17	freund	freund	PROPN
fnp-3050	866	18	t	t	PROPN
fnp-3050	866	19	,	,	PUNCT
fnp-3050	866	20	cuello	cuello	PROPN
fnp-3050	866	21	ac	ac	PROPN
fnp-3050	866	22	(	(	PUNCT
fnp-3050	866	23	2018	2018	NUM
fnp-3050	866	24	)	)	PUNCT
fnp-3050	866	25	evidence	evidence	NOUN
fnp-3050	866	26	of	of	ADP
fnp-3050	866	27	intraneuronal	intraneuronal	ADJ
fnp-3050	866	28	abeta	abeta	PROPN
fnp-3050	866	29	accumulation	accumulation	NOUN
fnp-3050	866	30	preceding	precede	VERB
fnp-3050	866	31	tau	tau	PROPN
fnp-3050	866	32	pathology	pathology	NOUN
fnp-3050	866	33	in	in	ADP
fnp-3050	866	34	the	the	DET
fnp-3050	866	35	entorhinal	entorhinal	ADJ
fnp-3050	866	36	cortex	cortex	NOUN
fnp-3050	866	37	.	.	PUNCT
fnp-3050	867	1	acta	acta	PROPN
fnp-3050	867	2	neuropathol	neuropathol	PROPN
fnp-3050	867	3	136:901	136:901	PROPN
fnp-3050	867	4	-	-	PUNCT
fnp-3050	867	5	917	917	NUM
fnp-3050	867	6	172	172	NUM
fnp-3050	867	7	.	.	PUNCT
fnp-3050	868	1	wang	wang	PROPN
fnp-3050	868	2	l	l	PROPN
fnp-3050	868	3	,	,	PUNCT
fnp-3050	868	4	benzinger	benzinger	PROPN
fnp-3050	868	5	tl	tl	PROPN
fnp-3050	868	6	,	,	PUNCT
fnp-3050	868	7	su	su	PROPN
fnp-3050	868	8	y	y	PROPN
fnp-3050	868	9	,	,	PUNCT
fnp-3050	868	10	christensen	christensen	PROPN
fnp-3050	868	11	j	j	PROPN
fnp-3050	868	12	,	,	PUNCT
fnp-3050	868	13	friedrichsen	friedrichsen	PROPN
fnp-3050	868	14	k	k	NOUN
fnp-3050	868	15	,	,	PUNCT
fnp-3050	868	16	aldea	aldea	NOUN
fnp-3050	868	17	p	p	NOUN
fnp-3050	868	18	,	,	PUNCT
fnp-3050	868	19	mcconathy	mcconathy	PROPN
fnp-3050	868	20	j	j	PROPN
fnp-3050	868	21	,	,	PUNCT
fnp-3050	868	22	cairns	cairns	PROPN
fnp-3050	868	23	nj	nj	PROPN
fnp-3050	868	24	,	,	PUNCT
fnp-3050	868	25	fagan	fagan	PROPN
fnp-3050	868	26	am	am	PROPN
fnp-3050	868	27	,	,	PUNCT
fnp-3050	868	28	morris	morris	PROPN
fnp-3050	868	29	jc	jc	PROPN
fnp-3050	868	30	,	,	PUNCT
fnp-3050	868	31	ances	ance	NOUN
fnp-3050	868	32	bm	bm	PROPN
fnp-3050	868	33	(	(	PUNCT
fnp-3050	868	34	2016	2016	NUM
fnp-3050	868	35	)	)	PUNCT
fnp-3050	868	36	evaluation	evaluation	NOUN
fnp-3050	868	37	of	of	ADP
fnp-3050	868	38	tau	tau	PROPN
fnp-3050	868	39	imaging	imaging	NOUN
fnp-3050	868	40	in	in	ADP
fnp-3050	868	41	staging	stage	VERB
fnp-3050	868	42	alzheimer	alzheimer	NOUN
fnp-3050	868	43	disease	disease	NOUN
fnp-3050	868	44	and	and	CCONJ
fnp-3050	868	45	revealing	reveal	VERB
fnp-3050	868	46	interactions	interaction	NOUN
fnp-3050	868	47	between	between	ADP
fnp-3050	868	48	beta	beta	NOUN
fnp-3050	868	49	-	-	PUNCT
fnp-3050	868	50	amyloid	amyloid	NOUN
fnp-3050	868	51	and	and	CCONJ
fnp-3050	868	52	tauopathy	tauopathy	NOUN
fnp-3050	868	53	.	.	PUNCT
fnp-3050	869	1	jama	jama	PROPN
fnp-3050	869	2	neurol	neurol	PROPN
fnp-3050	869	3	73:1070	73:1070	PROPN
fnp-3050	869	4	-	-	SYM
fnp-3050	869	5	1077	1077	NUM
fnp-3050	869	6	173	173	NUM
fnp-3050	869	7	.	.	PUNCT
fnp-3050	870	1	sardar	sardar	PROPN
fnp-3050	870	2	sinha	sinha	PROPN
fnp-3050	870	3	m	m	PROPN
fnp-3050	870	4	,	,	PUNCT
fnp-3050	870	5	ansell	ansell	PROPN
fnp-3050	870	6	-	-	PUNCT
fnp-3050	870	7	schultz	schultz	PROPN
fnp-3050	870	8	a	a	PRON
fnp-3050	870	9	,	,	PUNCT
fnp-3050	870	10	civitelli	civitelli	PROPN
fnp-3050	870	11	l	l	PROPN
fnp-3050	870	12	,	,	PUNCT
fnp-3050	870	13	hildesjö	hildesjö	PROPN
fnp-3050	870	14	c	c	PROPN
fnp-3050	870	15	,	,	PUNCT
fnp-3050	870	16	larsson	larsson	PROPN
fnp-3050	870	17	m	m	PROPN
fnp-3050	870	18	,	,	PUNCT
fnp-3050	870	19	lannfelt	lannfelt	VERB
fnp-3050	870	20	l	l	NOUN
fnp-3050	870	21	,	,	PUNCT
fnp-3050	870	22	ingelsson	ingelsson	PROPN
fnp-3050	870	23	m	m	PROPN
fnp-3050	870	24	,	,	PUNCT
fnp-3050	870	25	hallbeck	hallbeck	PROPN
fnp-3050	870	26	m	m	PROPN
fnp-3050	870	27	(	(	PUNCT
fnp-3050	870	28	2018	2018	NUM
fnp-3050	870	29	)	)	PUNCT
fnp-3050	870	30	alzheimer	alzheimer	PROPN
fnp-3050	870	31	's	's	PART
fnp-3050	870	32	disease	disease	NOUN
fnp-3050	870	33	pathology	pathology	NOUN
fnp-3050	870	34	propagation	propagation	NOUN
fnp-3050	870	35	by	by	ADP
fnp-3050	870	36	exosomes	exosome	NOUN
fnp-3050	870	37	containing	contain	VERB
fnp-3050	870	38	toxic	toxic	ADJ
fnp-3050	870	39	amyloid	amyloid	NOUN
fnp-3050	870	40	-	-	PUNCT
fnp-3050	870	41	beta	beta	NOUN
fnp-3050	870	42	oligomers	oligomer	NOUN
fnp-3050	870	43	.	.	PUNCT
fnp-3050	871	1	acta	acta	PROPN
fnp-3050	871	2	neuropathol	neuropathol	PROPN
fnp-3050	871	3	136:41	136:41	PROPN
fnp-3050	871	4	-	-	SYM
fnp-3050	871	5	56	56	NUM
fnp-3050	871	6	174	174	NUM
fnp-3050	871	7	.	.	PUNCT
fnp-3050	872	1	king	king	PROPN
fnp-3050	872	2	a	a	PROPN
fnp-3050	872	3	,	,	PUNCT
fnp-3050	872	4	bodi	bodi	PROPN
fnp-3050	872	5	i	i	PROPN
fnp-3050	872	6	,	,	PUNCT
fnp-3050	872	7	troakes	troake	VERB
fnp-3050	872	8	c	c	PROPN
fnp-3050	872	9	(	(	PUNCT
fnp-3050	872	10	2020	2020	NUM
fnp-3050	872	11	)	)	PUNCT
fnp-3050	872	12	the	the	DET
fnp-3050	872	13	neuropathological	neuropathological	ADJ
fnp-3050	872	14	diagnosis	diagnosis	NOUN
fnp-3050	872	15	of	of	ADP
fnp-3050	872	16	alzheimer	alzheimer	PROPN
fnp-3050	872	17	's	's	PART
fnp-3050	872	18	disease	disease	NOUN
fnp-3050	872	19	the	the	DET
fnp-3050	872	20	challenges	challenge	NOUN
fnp-3050	872	21	of	of	ADP
fnp-3050	872	22	pathological	pathological	ADJ
fnp-3050	872	23	mimics	mimic	NOUN
fnp-3050	872	24	and	and	CCONJ
fnp-3050	872	25	concomitant	concomitant	ADJ
fnp-3050	872	26	pathology	pathology	NOUN
fnp-3050	872	27	.	.	PUNCT
fnp-3050	873	1	brain	brain	PROPN
fnp-3050	873	2	sci	sci	PROPN
fnp-3050	873	3	10:479	10:479	PROPN
fnp-3050	873	4	175	175	NUM
fnp-3050	873	5	.	.	PUNCT
fnp-3050	874	1	gulisano	gulisano	PROPN
fnp-3050	874	2	w	w	PROPN
fnp-3050	874	3	,	,	PUNCT
fnp-3050	874	4	maugeri	maugeri	ADJ
fnp-3050	874	5	d	d	PROPN
fnp-3050	874	6	,	,	PUNCT
fnp-3050	874	7	baltrons	baltron	NOUN
fnp-3050	874	8	ma	ma	PROPN
fnp-3050	874	9	,	,	PUNCT
fnp-3050	874	10	fà	fà	ADV
fnp-3050	874	11	m	m	PROPN
fnp-3050	874	12	,	,	PUNCT
fnp-3050	874	13	amato	amato	PROPN
fnp-3050	874	14	a	a	X
fnp-3050	874	15	,	,	PUNCT
fnp-3050	874	16	palmeri	palmeri	VERB
fnp-3050	874	17	a	a	DET
fnp-3050	874	18	,	,	PUNCT
fnp-3050	874	19	d'adamio	d'adamio	PROPN
fnp-3050	874	20	l	l	NOUN
fnp-3050	874	21	,	,	PUNCT
fnp-3050	874	22	grassi	grassi	PROPN
fnp-3050	874	23	c	c	PROPN
fnp-3050	874	24	,	,	PUNCT
fnp-3050	874	25	devanand	devanand	NOUN
fnp-3050	874	26	dp	dp	PROPN
fnp-3050	874	27	,	,	PUNCT
fnp-3050	874	28	honig	honig	PROPN
fnp-3050	874	29	ls	ls	PROPN
fnp-3050	874	30	,	,	PUNCT
fnp-3050	874	31	puzzo	puzzo	X
fnp-3050	874	32	d	d	NOUN
fnp-3050	874	33	,	,	PUNCT
fnp-3050	874	34	arancio	arancio	PROPN
fnp-3050	874	35	o	o	X
fnp-3050	874	36	(	(	PUNCT
fnp-3050	874	37	2018	2018	NUM
fnp-3050	874	38	)	)	PUNCT
fnp-3050	874	39	role	role	NOUN
fnp-3050	874	40	of	of	ADP
fnp-3050	874	41	amyloid	amyloid	NOUN
fnp-3050	874	42	-	-	PUNCT
fnp-3050	874	43	beta	beta	NOUN
fnp-3050	874	44	and	and	CCONJ
fnp-3050	874	45	tau	tau	PROPN
fnp-3050	874	46	proteins	protein	NOUN
fnp-3050	874	47	in	in	ADP
fnp-3050	874	48	alzheimer	alzheimer	PROPN
fnp-3050	874	49	's	's	PART
fnp-3050	874	50	disease	disease	NOUN
fnp-3050	874	51	:	:	PUNCT
fnp-3050	874	52	confuting	confute	VERB
fnp-3050	874	53	the	the	DET
fnp-3050	874	54	amyloid	amyloid	NOUN
fnp-3050	874	55	cascade	cascade	NOUN
fnp-3050	874	56	.	.	PUNCT
fnp-3050	875	1	j	j	PROPN
fnp-3050	875	2	alzheimers	alzheimers	PROPN
fnp-3050	875	3	dis	dis	PROPN
fnp-3050	875	4	64	64	NUM
fnp-3050	875	5	:	:	PUNCT
fnp-3050	875	6	s611	s611	PROPN
fnp-3050	875	7	-	-	PUNCT
fnp-3050	875	8	s631	s631	PROPN
fnp-3050	875	9	176	176	NUM
fnp-3050	875	10	.	.	PUNCT
fnp-3050	876	1	small	small	PROPN
fnp-3050	876	2	sa	sa	PROPN
fnp-3050	876	3	,	,	PUNCT
fnp-3050	876	4	duff	duff	PROPN
fnp-3050	876	5	k	k	PROPN
fnp-3050	876	6	(	(	PUNCT
fnp-3050	876	7	2008	2008	NUM
fnp-3050	876	8	)	)	PUNCT
fnp-3050	876	9	linking	link	VERB
fnp-3050	876	10	abeta	abeta	ADV
fnp-3050	876	11	and	and	CCONJ
fnp-3050	876	12	tau	tau	PROPN
fnp-3050	876	13	in	in	ADP
fnp-3050	876	14	late	late	ADJ
fnp-3050	876	15	-	-	PUNCT
fnp-3050	876	16	onset	onset	NOUN
fnp-3050	876	17	alzheimer	alzheimer	NOUN
fnp-3050	876	18	's	's	PART
fnp-3050	876	19	disease	disease	NOUN
fnp-3050	876	20	:	:	PUNCT
fnp-3050	876	21	a	a	DET
fnp-3050	876	22	dual	dual	ADJ
fnp-3050	876	23	pathway	pathway	NOUN
fnp-3050	876	24	hypothesis	hypothesis	NOUN
fnp-3050	876	25	.	.	PUNCT
fnp-3050	877	1	neuron	neuron	PROPN
fnp-3050	877	2	60:534	60:534	PROPN
fnp-3050	877	3	-	-	SYM
fnp-3050	877	4	542	542	NUM
fnp-3050	877	5	177	177	NUM
fnp-3050	877	6	.	.	PUNCT
fnp-3050	878	1	rice	rice	NOUN
fnp-3050	878	2	hc	hc	PROPN
fnp-3050	878	3	,	,	PUNCT
fnp-3050	878	4	de	de	X
fnp-3050	878	5	malmazet	malmazet	PROPN
fnp-3050	878	6	d	d	PROPN
fnp-3050	878	7	,	,	PUNCT
fnp-3050	878	8	schreurs	schreur	VERB
fnp-3050	878	9	a	a	DET
fnp-3050	878	10	,	,	PUNCT
fnp-3050	878	11	frere	frere	PROPN
fnp-3050	878	12	s	s	PART
fnp-3050	878	13	,	,	PUNCT
fnp-3050	878	14	van	van	PROPN
fnp-3050	878	15	molle	molle	PROPN
fnp-3050	878	16	i	i	PROPN
fnp-3050	878	17	,	,	PUNCT
fnp-3050	878	18	volkov	volkov	PROPN
fnp-3050	878	19	an	an	PROPN
fnp-3050	878	20	,	,	PUNCT
fnp-3050	878	21	creemers	creemer	NOUN
fnp-3050	878	22	e	e	NOUN
fnp-3050	878	23	,	,	PUNCT
fnp-3050	878	24	vertkin	vertkin	VERB
fnp-3050	878	25	i	i	PRON
fnp-3050	878	26	,	,	PUNCT
fnp-3050	878	27	nys	nys	PROPN
fnp-3050	878	28	j	j	PROPN
fnp-3050	878	29	,	,	PUNCT
fnp-3050	878	30	ranaivoson	ranaivoson	PROPN
fnp-3050	878	31	fm	fm	PROPN
fnp-3050	878	32	,	,	PUNCT
fnp-3050	878	33	comoletti	comoletti	PROPN
fnp-3050	878	34	d	d	PROPN
fnp-3050	878	35	,	,	PUNCT
fnp-3050	878	36	savas	savas	PROPN
fnp-3050	878	37	jn	jn	PROPN
fnp-3050	878	38	,	,	PUNCT
fnp-3050	878	39	remaut	remaut	PROPN
fnp-3050	878	40	h	h	PROPN
fnp-3050	878	41	,	,	PUNCT
fnp-3050	878	42	balschun	balschun	PROPN
fnp-3050	878	43	d	d	PROPN
fnp-3050	878	44	,	,	PUNCT
fnp-3050	878	45	wierda	wierda	PROPN
fnp-3050	878	46	kd	kd	PROPN
fnp-3050	878	47	,	,	PUNCT
fnp-3050	878	48	slutsky	slutsky	PROPN
fnp-3050	878	49	i	i	PROPN
fnp-3050	878	50	,	,	PUNCT
fnp-3050	878	51	farrow	farrow	PROPN
fnp-3050	878	52	k	k	PROPN
fnp-3050	878	53	,	,	PUNCT
fnp-3050	878	54	de	de	PROPN
fnp-3050	878	55	strooper	strooper	NOUN
fnp-3050	878	56	b	b	PROPN
fnp-3050	878	57	,	,	PUNCT
fnp-3050	878	58	de	de	X
fnp-3050	878	59	wit	wit	ADJ
fnp-3050	878	60	j	j	PROPN
fnp-3050	878	61	(	(	PUNCT
fnp-3050	878	62	2019	2019	NUM
fnp-3050	878	63	)	)	PUNCT
fnp-3050	878	64	secreted	secrete	VERB
fnp-3050	878	65	amyloid	amyloid	NOUN
fnp-3050	878	66	-	-	PUNCT
fnp-3050	878	67	beta	beta	NOUN
fnp-3050	878	68	precursor	precursor	NOUN
fnp-3050	878	69	protein	protein	NOUN
fnp-3050	878	70	functions	function	NOUN
fnp-3050	878	71	as	as	ADP
fnp-3050	878	72	a	a	DET
fnp-3050	878	73	gababr1a	gababr1a	ADJ
fnp-3050	878	74	ligand	ligand	NOUN
fnp-3050	878	75	to	to	PART
fnp-3050	878	76	modulate	modulate	VERB
fnp-3050	878	77	synaptic	synaptic	ADJ
fnp-3050	878	78	transmission	transmission	NOUN
fnp-3050	878	79	.	.	PUNCT
fnp-3050	879	1	science	science	NOUN
fnp-3050	879	2	363	363	NUM
fnp-3050	879	3	:	:	PUNCT
fnp-3050	879	4	eaao4827	eaao4827	PROPN
fnp-3050	879	5	,	,	PUNCT
fnp-3050	879	6	doi	doi	PROPN
fnp-3050	879	7	4810.1126	4810.1126	PROPN
fnp-3050	879	8	/	/	SYM
fnp-3050	879	9	science.aao4827	science.aao4827	PROPN
fnp-3050	879	10	178	178	NUM
fnp-3050	879	11	.	.	PUNCT
fnp-3050	880	1	ruiz	ruiz	NOUN
fnp-3050	880	2	-	-	PUNCT
fnp-3050	880	3	riquelme	riquelme	PROPN
fnp-3050	880	4	a	a	PRON
fnp-3050	880	5	,	,	PUNCT
fnp-3050	880	6	lau	lau	PROPN
fnp-3050	880	7	hhc	hhc	PROPN
fnp-3050	880	8	,	,	PUNCT
fnp-3050	880	9	stuart	stuart	PROPN
fnp-3050	880	10	e	e	PROPN
fnp-3050	880	11	,	,	PUNCT
fnp-3050	880	12	goczi	goczi	PROPN
fnp-3050	880	13	an	an	PROPN
fnp-3050	880	14	,	,	PUNCT
fnp-3050	880	15	wang	wang	PROPN
fnp-3050	880	16	z	z	PROPN
fnp-3050	880	17	,	,	PUNCT
fnp-3050	880	18	schmitt	schmitt	NOUN
fnp-3050	880	19	-	-	PUNCT
fnp-3050	880	20	ulms	ulm	NOUN
fnp-3050	880	21	g	g	NOUN
fnp-3050	880	22	,	,	PUNCT
fnp-3050	880	23	watts	watts	PROPN
fnp-3050	880	24	jc	jc	PROPN
fnp-3050	880	25	(	(	PUNCT
fnp-3050	880	26	2018	2018	NUM
fnp-3050	880	27	)	)	PUNCT
fnp-3050	880	28	prion	prion	NOUN
fnp-3050	880	29	-	-	PUNCT
fnp-3050	880	30	like	like	ADJ
fnp-3050	880	31	propagation	propagation	NOUN
fnp-3050	880	32	of	of	ADP
fnp-3050	880	33	beta	beta	NOUN
fnp-3050	880	34	-	-	PUNCT
fnp-3050	880	35	amyloid	amyloid	NOUN
fnp-3050	880	36	aggregates	aggregate	NOUN
fnp-3050	880	37	in	in	ADP
fnp-3050	880	38	the	the	DET
fnp-3050	880	39	absence	absence	NOUN
fnp-3050	880	40	of	of	ADP
fnp-3050	880	41	app	app	NOUN
fnp-3050	880	42	overexpression	overexpression	NOUN
fnp-3050	880	43	.	.	PUNCT
fnp-3050	881	1	acta	acta	PROPN
fnp-3050	881	2	neuropathol	neuropathol	PROPN
fnp-3050	881	3	commun	commun	PROPN
fnp-3050	881	4	6:26	6:26	PROPN
fnp-3050	881	5	179	179	NUM
fnp-3050	881	6	.	.	PUNCT
fnp-3050	882	1	pickett	pickett	PROPN
fnp-3050	882	2	ek	ek	PROPN
fnp-3050	882	3	,	,	PUNCT
fnp-3050	882	4	koffie	koffie	PROPN
fnp-3050	882	5	rm	rm	PROPN
fnp-3050	882	6	,	,	PUNCT
fnp-3050	882	7	wegmann	wegmann	PROPN
fnp-3050	882	8	s	s	PROPN
fnp-3050	882	9	,	,	PUNCT
fnp-3050	882	10	henstridge	henstridge	PROPN
fnp-3050	882	11	cm	cm	PROPN
fnp-3050	882	12	,	,	PUNCT
fnp-3050	882	13	herrmann	herrmann	PROPN
fnp-3050	882	14	ag	ag	PROPN
fnp-3050	882	15	,	,	PUNCT
fnp-3050	882	16	colom	colom	PROPN
fnp-3050	882	17	-	-	PROPN
fnp-3050	882	18	cadena	cadena	PROPN
fnp-3050	882	19	m	m	PROPN
fnp-3050	882	20	,	,	PUNCT
fnp-3050	882	21	lleo	lleo	PROPN
fnp-3050	882	22	a	a	PRON
fnp-3050	882	23	,	,	PUNCT
fnp-3050	882	24	kay	kay	PROPN
fnp-3050	882	25	kr	kr	PROPN
fnp-3050	882	26	,	,	PUNCT
fnp-3050	882	27	vaught	vaught	PROPN
fnp-3050	882	28	m	m	PROPN
fnp-3050	882	29	,	,	PUNCT
fnp-3050	882	30	soberman	soberman	NOUN
fnp-3050	882	31	r	r	PROPN
fnp-3050	882	32	,	,	PUNCT
fnp-3050	882	33	walsh	walsh	PROPN
fnp-3050	882	34	dm	dm	PROPN
fnp-3050	882	35	,	,	PUNCT
fnp-3050	882	36	hyman	hyman	PROPN
fnp-3050	882	37	bt	bt	PROPN
fnp-3050	882	38	,	,	PUNCT
fnp-3050	882	39	spires	spire	NOUN
fnp-3050	882	40	-	-	PUNCT
fnp-3050	882	41	jones	jones	NOUN
fnp-3050	882	42	tl	tl	PROPN
fnp-3050	882	43	(	(	PUNCT
fnp-3050	882	44	2016	2016	NUM
fnp-3050	882	45	)	)	PUNCT
fnp-3050	882	46	non	non	ADJ
fnp-3050	882	47	-	-	ADJ
fnp-3050	882	48	fibrillar	fibrillar	ADJ
fnp-3050	882	49	oligomeric	oligomeric	ADJ
fnp-3050	882	50	amyloid	amyloid	NOUN
fnp-3050	882	51	-	-	PUNCT
fnp-3050	882	52	beta	beta	NOUN
fnp-3050	882	53	within	within	ADP
fnp-3050	882	54	synapses	synapsis	NOUN
fnp-3050	882	55	.	.	PUNCT
fnp-3050	883	1	j	j	PROPN
fnp-3050	883	2	alzheimers	alzheimers	PROPN
fnp-3050	883	3	dis	dis	PROPN
fnp-3050	883	4	53:787	53:787	NUM
fnp-3050	883	5	-	-	SYM
fnp-3050	883	6	800	800	NUM
fnp-3050	883	7	180	180	NUM
fnp-3050	883	8	.	.	PUNCT
fnp-3050	883	9	mroczko	mroczko	PROPN
fnp-3050	883	10	b	b	PROPN
fnp-3050	883	11	,	,	PUNCT
fnp-3050	883	12	groblewska	groblewska	PROPN
fnp-3050	883	13	m	m	PROPN
fnp-3050	883	14	,	,	PUNCT
fnp-3050	883	15	litman	litman	NOUN
fnp-3050	883	16	-	-	PUNCT
fnp-3050	883	17	zawadzka	zawadzka	PROPN
fnp-3050	883	18	a	a	PRON
fnp-3050	883	19	,	,	PUNCT
fnp-3050	883	20	kornhuber	kornhuber	PROPN
fnp-3050	883	21	j	j	PROPN
fnp-3050	883	22	,	,	PUNCT
fnp-3050	883	23	lewczuk	lewczuk	PROPN
fnp-3050	883	24	p	p	X
fnp-3050	883	25	(	(	PUNCT
fnp-3050	883	26	2018	2018	NUM
fnp-3050	883	27	)	)	PUNCT
fnp-3050	883	28	amyloid	amyloid	NOUN
fnp-3050	883	29	ß	ß	PRON
fnp-3050	883	30	oligomers	oligomer	NOUN
fnp-3050	883	31	(	(	PUNCT
fnp-3050	883	32	aßos	aßos	ADJ
fnp-3050	883	33	)	)	PUNCT
fnp-3050	883	34	in	in	ADP
fnp-3050	883	35	alzheimer	alzheimer	PROPN
fnp-3050	883	36	's	's	PART
fnp-3050	883	37	disease	disease	NOUN
fnp-3050	883	38	.	.	PUNCT
fnp-3050	884	1	j	j	PROPN
fnp-3050	884	2	neural	neural	ADJ
fnp-3050	884	3	transm	transm	PROPN
fnp-3050	884	4	(	(	PUNCT
fnp-3050	884	5	vienna	vienna	PROPN
fnp-3050	884	6	)	)	PUNCT
fnp-3050	884	7	125:177	125:177	NUM
fnp-3050	884	8	-	-	SYM
fnp-3050	884	9	191	191	NUM
fnp-3050	884	10	181	181	NUM
fnp-3050	884	11	.	.	PUNCT
fnp-3050	885	1	koss	koss	PROPN
fnp-3050	885	2	dj	dj	PROPN
fnp-3050	885	3	,	,	PUNCT
fnp-3050	885	4	jones	jones	PROPN
fnp-3050	885	5	g	g	PROPN
fnp-3050	885	6	,	,	PUNCT
fnp-3050	885	7	cranston	cranston	PROPN
fnp-3050	885	8	a	a	X
fnp-3050	885	9	,	,	PUNCT
fnp-3050	885	10	gardner	gardner	PROPN
fnp-3050	885	11	h	h	PROPN
fnp-3050	885	12	,	,	PUNCT
fnp-3050	885	13	kanaan	kanaan	PROPN
fnp-3050	885	14	nm	nm	PROPN
fnp-3050	885	15	,	,	PUNCT
fnp-3050	885	16	platt	platt	PROPN
fnp-3050	885	17	b	b	PROPN
fnp-3050	885	18	(	(	PUNCT
fnp-3050	885	19	2016	2016	NUM
fnp-3050	885	20	)	)	PUNCT
fnp-3050	885	21	soluble	soluble	ADJ
fnp-3050	885	22	pre	pre	ADJ
fnp-3050	885	23	-	-	ADJ
fnp-3050	885	24	fibrillar	fibrillar	ADJ
fnp-3050	885	25	tau	tau	NOUN
fnp-3050	885	26	and	and	CCONJ
fnp-3050	885	27	beta	beta	NOUN
fnp-3050	885	28	-	-	PUNCT
fnp-3050	885	29	amyloid	amyloid	NOUN
fnp-3050	885	30	species	specie	NOUN
fnp-3050	885	31	emerge	emerge	VERB
fnp-3050	885	32	in	in	ADP
fnp-3050	885	33	early	early	ADJ
fnp-3050	885	34	human	human	PROPN
fnp-3050	885	35	alzheimer	alzheimer	PROPN
fnp-3050	885	36	's	's	PART
fnp-3050	885	37	disease	disease	NOUN
fnp-3050	885	38	and	and	CCONJ
fnp-3050	885	39	track	track	NOUN
fnp-3050	885	40	disease	disease	NOUN
fnp-3050	885	41	progression	progression	NOUN
fnp-3050	885	42	and	and	CCONJ
fnp-3050	885	43	cognitive	cognitive	ADJ
fnp-3050	885	44	decline	decline	NOUN
fnp-3050	885	45	.	.	PUNCT
fnp-3050	886	1	acta	acta	PROPN
fnp-3050	886	2	neuropathol	neuropathol	PROPN
fnp-3050	886	3	132:875	132:875	PROPN
fnp-3050	886	4	-	-	SYM
fnp-3050	886	5	895	895	NUM
fnp-3050	886	6	182	182	NUM
fnp-3050	886	7	.	.	PUNCT
fnp-3050	887	1	takahashi	takahashi	PROPN
fnp-3050	887	2	rh	rh	PROPN
fnp-3050	887	3	,	,	PUNCT
fnp-3050	887	4	capetillo	capetillo	PROPN
fnp-3050	887	5	-	-	PUNCT
fnp-3050	887	6	zarate	zarate	NOUN
fnp-3050	887	7	e	e	PROPN
fnp-3050	887	8	,	,	PUNCT
fnp-3050	887	9	lin	lin	PROPN
fnp-3050	887	10	mt	mt	PROPN
fnp-3050	887	11	,	,	PUNCT
fnp-3050	887	12	milner	milner	PROPN
fnp-3050	887	13	ta	ta	PROPN
fnp-3050	887	14	,	,	PUNCT
fnp-3050	887	15	gouras	gouras	PROPN
fnp-3050	887	16	gk	gk	PROPN
fnp-3050	887	17	(	(	PUNCT
fnp-3050	887	18	2010	2010	NUM
fnp-3050	887	19	)	)	PUNCT
fnp-3050	887	20	co	co	NOUN
fnp-3050	887	21	-	-	NOUN
fnp-3050	887	22	occurrence	occurrence	NOUN
fnp-3050	887	23	of	of	ADP
fnp-3050	887	24	alzheimer	alzheimer	PROPN
fnp-3050	887	25	's	's	PART
fnp-3050	887	26	disease	disease	NOUN
fnp-3050	887	27	beta	beta	NOUN
fnp-3050	887	28	-	-	PUNCT
fnp-3050	887	29	amyloid	amyloid	NOUN
fnp-3050	887	30	and	and	CCONJ
fnp-3050	887	31	tau	tau	PROPN
fnp-3050	887	32	pathologies	pathology	NOUN
fnp-3050	887	33	at	at	ADP
fnp-3050	887	34	synapses	synapsis	NOUN
fnp-3050	887	35	.	.	PUNCT
fnp-3050	888	1	neurobiol	neurobiol	VERB
fnp-3050	888	2	aging	age	VERB
fnp-3050	888	3	31:1145	31:1145	NUM
fnp-3050	888	4	-	-	SYM
fnp-3050	888	5	1152	1152	NUM
fnp-3050	888	6	183	183	NUM
fnp-3050	888	7	.	.	PUNCT
fnp-3050	889	1	rajmohan	rajmohan	PROPN
fnp-3050	889	2	r	r	PROPN
fnp-3050	889	3	,	,	PUNCT
fnp-3050	889	4	reddy	reddy	PROPN
fnp-3050	889	5	ph	ph	PROPN
fnp-3050	889	6	(	(	PUNCT
fnp-3050	889	7	2017	2017	NUM
fnp-3050	889	8	)	)	PUNCT
fnp-3050	889	9	amyloid	amyloid	NOUN
fnp-3050	889	10	-	-	PUNCT
fnp-3050	889	11	beta	beta	NOUN
fnp-3050	889	12	and	and	CCONJ
fnp-3050	889	13	phosphorylated	phosphorylate	VERB
fnp-3050	889	14	tau	tau	PROPN
fnp-3050	889	15	accumulations	accumulation	NOUN
fnp-3050	889	16	cause	cause	VERB
fnp-3050	889	17	abnormalities	abnormality	NOUN
fnp-3050	889	18	at	at	ADP
fnp-3050	889	19	synapses	synapsis	NOUN
fnp-3050	889	20	of	of	ADP
fnp-3050	889	21	alzheimer	alzheimer	PROPN
fnp-3050	889	22	's	's	PART
fnp-3050	889	23	disease	disease	NOUN
fnp-3050	889	24	neurons	neuron	NOUN
fnp-3050	889	25	.	.	PUNCT
fnp-3050	890	1	j	j	PROPN
fnp-3050	890	2	alzheimers	alzheimers	PROPN
fnp-3050	890	3	dis	dis	PROPN
fnp-3050	890	4	57:975	57:975	PROPN
fnp-3050	890	5	-	-	SYM
fnp-3050	890	6	999	999	NUM
fnp-3050	890	7	184	184	NUM
fnp-3050	890	8	.	.	PUNCT
fnp-3050	891	1	van	van	PROPN
fnp-3050	891	2	der	der	PROPN
fnp-3050	891	3	kant	kant	PROPN
fnp-3050	891	4	r	r	PROPN
fnp-3050	891	5	,	,	PUNCT
fnp-3050	891	6	goldstein	goldstein	PROPN
fnp-3050	891	7	lsb	lsb	PROPN
fnp-3050	891	8	,	,	PUNCT
fnp-3050	891	9	ossenkoppele	ossenkoppele	PROPN
fnp-3050	891	10	r	r	PROPN
fnp-3050	891	11	(	(	PUNCT
fnp-3050	891	12	2020	2020	NUM
fnp-3050	891	13	)	)	PUNCT
fnp-3050	891	14	amyloid	amyloid	NOUN
fnp-3050	891	15	-	-	PUNCT
fnp-3050	891	16	beta	beta	NOUN
fnp-3050	891	17	-	-	PUNCT
fnp-3050	891	18	independent	independent	ADJ
fnp-3050	891	19	regulators	regulator	NOUN
fnp-3050	891	20	of	of	ADP
fnp-3050	891	21	tau	tau	PROPN
fnp-3050	891	22	pathology	pathology	NOUN
fnp-3050	891	23	in	in	ADP
fnp-3050	891	24	alzheimer	alzheimer	PROPN
fnp-3050	891	25	disease	disease	PROPN
fnp-3050	891	26	.	.	PUNCT
fnp-3050	892	1	nat	nat	PROPN
fnp-3050	892	2	rev	rev	VERB
fnp-3050	892	3	neurosci	neurosci	PROPN
fnp-3050	892	4	21:21	21:21	NUM
fnp-3050	892	5	-	-	SYM
fnp-3050	892	6	35	35	NUM
fnp-3050	892	7	185	185	NUM
fnp-3050	892	8	.	.	PUNCT
fnp-3050	893	1	horie	horie	PROPN
fnp-3050	893	2	k	k	PROPN
fnp-3050	893	3	,	,	PUNCT
fnp-3050	893	4	barthélemy	barthélemy	PROPN
fnp-3050	893	5	nr	nr	PROPN
fnp-3050	893	6	,	,	PUNCT
fnp-3050	893	7	mallipeddi	mallipeddi	ADJ
fnp-3050	893	8	n	n	CCONJ
fnp-3050	893	9	,	,	PUNCT
fnp-3050	893	10	li	li	PROPN
fnp-3050	893	11	y	y	PROPN
fnp-3050	893	12	,	,	PUNCT
fnp-3050	893	13	franklin	franklin	PROPN
fnp-3050	893	14	ee	ee	PROPN
fnp-3050	893	15	,	,	PUNCT
fnp-3050	893	16	perrin	perrin	PROPN
fnp-3050	893	17	rj	rj	PROPN
fnp-3050	893	18	,	,	PUNCT
fnp-3050	893	19	bateman	bateman	PROPN
fnp-3050	893	20	rj	rj	PROPN
fnp-3050	893	21	,	,	PUNCT
fnp-3050	893	22	sato	sato	PROPN
fnp-3050	893	23	c	c	PROPN
fnp-3050	893	24	(	(	PUNCT
fnp-3050	893	25	2020	2020	NUM
fnp-3050	893	26	)	)	PUNCT
fnp-3050	893	27	regional	regional	ADJ
fnp-3050	893	28	correlation	correlation	NOUN
fnp-3050	893	29	of	of	ADP
fnp-3050	893	30	biochemical	biochemical	ADJ
fnp-3050	893	31	measures	measure	NOUN
fnp-3050	893	32	of	of	ADP
fnp-3050	893	33	amyloid	amyloid	NOUN
fnp-3050	893	34	and	and	CCONJ
fnp-3050	893	35	tau	tau	PROPN
fnp-3050	893	36	phosphorylation	phosphorylation	NOUN
fnp-3050	893	37	in	in	ADP
fnp-3050	893	38	the	the	DET
fnp-3050	893	39	brain	brain	NOUN
fnp-3050	893	40	.	.	PUNCT
fnp-3050	894	1	acta	acta	PROPN
fnp-3050	894	2	neuropathol	neuropathol	PROPN
fnp-3050	894	3	commun	commun	PROPN
fnp-3050	894	4	8:149	8:149	NUM
fnp-3050	894	5	186	186	NUM
fnp-3050	894	6	.	.	PUNCT
fnp-3050	895	1	tripathi	tripathi	PROPN
fnp-3050	895	2	t	t	PROPN
fnp-3050	895	3	,	,	PUNCT
fnp-3050	895	4	khan	khan	PROPN
fnp-3050	895	5	h	h	PROPN
fnp-3050	895	6	(	(	PUNCT
fnp-3050	895	7	2020	2020	NUM
fnp-3050	895	8	)	)	PUNCT
fnp-3050	895	9	direct	direct	ADJ
fnp-3050	895	10	interaction	interaction	NOUN
fnp-3050	895	11	between	between	ADP
fnp-3050	895	12	the	the	DET
fnp-3050	895	13	beta	beta	NOUN
fnp-3050	895	14	-	-	PUNCT
fnp-3050	895	15	amyloid	amyloid	NOUN
fnp-3050	895	16	core	core	NOUN
fnp-3050	895	17	and	and	CCONJ
fnp-3050	895	18	tau	tau	PROPN
fnp-3050	895	19	facilitates	facilitate	VERB
fnp-3050	895	20	cross	cross	ADJ
fnp-3050	895	21	-	-	ADJ
fnp-3050	895	22	seeding	seeding	ADJ
fnp-3050	895	23	:	:	PUNCT
fnp-3050	895	24	a	a	DET
fnp-3050	895	25	novel	novel	ADJ
fnp-3050	895	26	target	target	NOUN
fnp-3050	895	27	for	for	ADP
fnp-3050	895	28	therapeutic	therapeutic	ADJ
fnp-3050	895	29	intervention	intervention	NOUN
fnp-3050	895	30	.	.	PUNCT
fnp-3050	896	1	biochemistry	biochemistry	NOUN
fnp-3050	896	2	59:341	59:341	PROPN
fnp-3050	896	3	-	-	SYM
fnp-3050	896	4	342	342	NUM
fnp-3050	896	5	187	187	NUM
fnp-3050	896	6	.	.	PUNCT
fnp-3050	897	1	catania	catania	PROPN
fnp-3050	897	2	m	m	PROPN
fnp-3050	897	3	,	,	PUNCT
fnp-3050	897	4	di	di	X
fnp-3050	897	5	fede	fede	PROPN
fnp-3050	897	6	g	g	PROPN
fnp-3050	897	7	(	(	PUNCT
fnp-3050	897	8	2020	2020	NUM
fnp-3050	897	9	)	)	PUNCT
fnp-3050	897	10	one	one	NUM
fnp-3050	897	11	or	or	CCONJ
fnp-3050	897	12	more	more	ADJ
fnp-3050	897	13	beta	beta	NOUN
fnp-3050	897	14	-	-	PUNCT
fnp-3050	897	15	amyloid(s	amyloid(s	NOUN
fnp-3050	897	16	)	)	PUNCT
fnp-3050	897	17	?	?	PUNCT
fnp-3050	898	1	new	new	ADJ
fnp-3050	898	2	insights	insight	NOUN
fnp-3050	898	3	into	into	ADP
fnp-3050	898	4	the	the	DET
fnp-3050	898	5	prion	prion	NOUN
fnp-3050	898	6	-	-	PUNCT
fnp-3050	898	7	like	like	ADJ
fnp-3050	898	8	nature	nature	NOUN
fnp-3050	898	9	of	of	ADP
fnp-3050	898	10	alzheimer	alzheimer	PROPN
fnp-3050	898	11	's	's	PART
fnp-3050	898	12	disease	disease	NOUN
fnp-3050	898	13	.	.	PUNCT
fnp-3050	899	1	prog	prog	NOUN
fnp-3050	899	2	mol	mol	ADP
fnp-3050	899	3	biol	biol	PROPN
fnp-3050	899	4	transl	transl	PROPN
fnp-3050	899	5	sci	sci	PROPN
fnp-3050	899	6	175:213	175:213	PROPN
fnp-3050	899	7	-	-	PUNCT
fnp-3050	899	8	237	237	NUM
fnp-3050	899	9	188	188	NUM
fnp-3050	899	10	.	.	PUNCT
fnp-3050	900	1	panza	panza	PROPN
fnp-3050	900	2	f	f	PROPN
fnp-3050	900	3	,	,	PUNCT
fnp-3050	900	4	lozupone	lozupone	NOUN
fnp-3050	900	5	m	m	PROPN
fnp-3050	900	6	,	,	PUNCT
fnp-3050	900	7	dibello	dibello	PROPN
fnp-3050	900	8	v	v	PROPN
fnp-3050	900	9	,	,	PUNCT
fnp-3050	900	10	greco	greco	PROPN
fnp-3050	900	11	a	a	X
fnp-3050	900	12	,	,	PUNCT
fnp-3050	900	13	daniele	daniele	PROPN
fnp-3050	900	14	a	a	PRON
fnp-3050	900	15	,	,	PUNCT
fnp-3050	900	16	seripa	seripa	ADJ
fnp-3050	900	17	d	d	NOUN
fnp-3050	900	18	,	,	PUNCT
fnp-3050	900	19	logroscino	logroscino	PROPN
fnp-3050	900	20	g	g	PROPN
fnp-3050	900	21	,	,	PUNCT
fnp-3050	900	22	imbimbo	imbimbo	PROPN
fnp-3050	900	23	bp	bp	PROPN
fnp-3050	900	24	(	(	PUNCT
fnp-3050	900	25	2019	2019	NUM
fnp-3050	900	26	)	)	PUNCT
fnp-3050	900	27	are	be	AUX
fnp-3050	900	28	antibodies	antibody	NOUN
fnp-3050	900	29	directed	direct	VERB
fnp-3050	900	30	against	against	ADP
fnp-3050	900	31	amyloid	amyloid	NOUN
fnp-3050	900	32	-	-	PUNCT
fnp-3050	900	33	beta	beta	NOUN
fnp-3050	900	34	(	(	PUNCT
fnp-3050	900	35	abeta	abeta	NOUN
fnp-3050	900	36	)	)	PUNCT
fnp-3050	900	37	oligomers	oligomer	NOUN
fnp-3050	900	38	the	the	DET
fnp-3050	900	39	last	last	ADJ
fnp-3050	900	40	call	call	NOUN
fnp-3050	900	41	for	for	ADP
fnp-3050	900	42	the	the	DET
fnp-3050	900	43	abeta	abeta	PROPN
fnp-3050	900	44	hypothesis	hypothesis	NOUN
fnp-3050	900	45	of	of	ADP
fnp-3050	900	46	alzheimer	alzheimer	PROPN
fnp-3050	900	47	's	's	PART
fnp-3050	900	48	disease	disease	NOUN
fnp-3050	900	49	?	?	PUNCT
fnp-3050	901	1	immunotherapy	immunotherapy	NOUN
fnp-3050	901	2	11:3	11:3	NUM
fnp-3050	901	3	-	-	SYM
fnp-3050	901	4	6	6	NUM
fnp-3050	901	5	189	189	NUM
fnp-3050	901	6	.	.	PUNCT
fnp-3050	902	1	kuang	kuang	PROPN
fnp-3050	902	2	h	h	PROPN
fnp-3050	902	3	,	,	PUNCT
fnp-3050	902	4	tan	tan	PROPN
fnp-3050	902	5	cy	cy	PROPN
fnp-3050	902	6	,	,	PUNCT
fnp-3050	902	7	tian	tian	PROPN
fnp-3050	902	8	hz	hz	PROPN
fnp-3050	902	9	,	,	PUNCT
fnp-3050	902	10	liu	liu	PROPN
fnp-3050	902	11	lh	lh	PROPN
fnp-3050	902	12	,	,	PUNCT
fnp-3050	902	13	yang	yang	PROPN
fnp-3050	902	14	mw	mw	PROPN
fnp-3050	902	15	,	,	PUNCT
fnp-3050	902	16	hong	hong	PROPN
fnp-3050	902	17	ff	ff	NOUN
fnp-3050	902	18	,	,	PUNCT
fnp-3050	902	19	yang	yang	PROPN
fnp-3050	902	20	sl	sl	PROPN
fnp-3050	902	21	(	(	PUNCT
fnp-3050	902	22	2020	2020	NUM
fnp-3050	902	23	)	)	PUNCT
fnp-3050	902	24	exploring	explore	VERB
fnp-3050	902	25	the	the	DET
fnp-3050	902	26	bi	bi	ADJ
fnp-3050	902	27	-	-	ADJ
fnp-3050	902	28	directional	directional	ADJ
fnp-3050	902	29	relationship	relationship	NOUN
fnp-3050	902	30	between	between	ADP
fnp-3050	902	31	autophagy	autophagy	NOUN
fnp-3050	902	32	and	and	CCONJ
fnp-3050	902	33	alzheimer	alzheimer	PROPN
fnp-3050	902	34	's	's	PART
fnp-3050	902	35	disease	disease	NOUN
fnp-3050	902	36	.	.	PUNCT
fnp-3050	903	1	cns	cns	PROPN
fnp-3050	903	2	neurosci	neurosci	PROPN
fnp-3050	903	3	ther	ther	ADV
fnp-3050	903	4	26:155	26:155	NUM
fnp-3050	903	5	-	-	SYM
fnp-3050	903	6	166	166	NUM
fnp-3050	903	7	190	190	NUM
fnp-3050	903	8	.	.	PUNCT
fnp-3050	904	1	jaunmuktane	jaunmuktane	PROPN
fnp-3050	904	2	z	z	PROPN
fnp-3050	904	3	,	,	PUNCT
fnp-3050	904	4	brandner	brandner	NOUN
fnp-3050	904	5	s	s	PART
fnp-3050	904	6	(	(	PUNCT
fnp-3050	904	7	2020	2020	NUM
fnp-3050	904	8	)	)	PUNCT
fnp-3050	904	9	the	the	DET
fnp-3050	904	10	role	role	NOUN
fnp-3050	904	11	of	of	ADP
fnp-3050	904	12	prion	prion	NOUN
fnp-3050	904	13	-	-	PUNCT
fnp-3050	904	14	like	like	ADJ
fnp-3050	904	15	mechanisms	mechanism	NOUN
fnp-3050	904	16	in	in	ADP
fnp-3050	904	17	neurodegenerative	neurodegenerative	ADJ
fnp-3050	904	18	diseases	disease	NOUN
fnp-3050	904	19	.	.	PUNCT
fnp-3050	905	1	neuropathol	neuropathol	NOUN
fnp-3050	905	2	appl	appl	PROPN
fnp-3050	905	3	neurobiol	neurobiol	PROPN
fnp-3050	905	4	46:522	46:522	NUM
fnp-3050	905	5	-	-	SYM
fnp-3050	905	6	545	545	NUM
fnp-3050	905	7	191	191	NUM
fnp-3050	905	8	.	.	PUNCT
fnp-3050	906	1	penke	penke	PROPN
fnp-3050	906	2	b	b	NOUN
fnp-3050	906	3	,	,	PUNCT
fnp-3050	906	4	szucs	szucs	PROPN
fnp-3050	906	5	m	m	PROPN
fnp-3050	906	6	,	,	PUNCT
fnp-3050	906	7	bogár	bogár	PROPN
fnp-3050	906	8	f	f	PROPN
fnp-3050	906	9	(	(	PUNCT
fnp-3050	906	10	2020	2020	NUM
fnp-3050	906	11	)	)	PUNCT
fnp-3050	906	12	oligomerization	oligomerization	NOUN
fnp-3050	906	13	and	and	CCONJ
fnp-3050	906	14	conformational	conformational	ADJ
fnp-3050	906	15	change	change	NOUN
fnp-3050	906	16	turn	turn	VERB
fnp-3050	906	17	monomeric	monomeric	ADJ
fnp-3050	906	18	beta	beta	NOUN
fnp-3050	906	19	-	-	PUNCT
fnp-3050	906	20	amyloid	amyloid	NOUN
fnp-3050	906	21	and	and	CCONJ
fnp-3050	906	22	tau	tau	PROPN
fnp-3050	906	23	proteins	protein	NOUN
fnp-3050	906	24	toxic	toxic	ADJ
fnp-3050	906	25	:	:	PUNCT
fnp-3050	906	26	their	their	PRON
fnp-3050	906	27	role	role	NOUN
fnp-3050	906	28	in	in	ADP
fnp-3050	906	29	alzheimer	alzheimer	PROPN
fnp-3050	906	30	's	's	PART
fnp-3050	906	31	pathogenesis	pathogenesis	NOUN
fnp-3050	906	32	.	.	PUNCT
fnp-3050	907	1	molecules	molecule	NOUN
fnp-3050	907	2	25	25	NUM
fnp-3050	907	3	192	192	NUM
fnp-3050	907	4	.	.	PUNCT
fnp-3050	908	1	dujardin	dujardin	PROPN
fnp-3050	908	2	s	s	PROPN
fnp-3050	908	3	,	,	PUNCT
fnp-3050	908	4	commins	commin	VERB
fnp-3050	908	5	c	c	NOUN
fnp-3050	908	6	,	,	PUNCT
fnp-3050	908	7	lathuiliere	lathuiliere	VERB
fnp-3050	908	8	a	a	DET
fnp-3050	908	9	,	,	PUNCT
fnp-3050	908	10	beerepoot	beerepoot	NOUN
fnp-3050	908	11	p	p	X
fnp-3050	908	12	,	,	PUNCT
fnp-3050	908	13	fernandes	fernandes	PROPN
fnp-3050	908	14	ar	ar	PROPN
fnp-3050	908	15	,	,	PUNCT
fnp-3050	908	16	kamath	kamath	PROPN
fnp-3050	908	17	tv	tv	PROPN
fnp-3050	908	18	,	,	PUNCT
fnp-3050	908	19	de	de	X
fnp-3050	908	20	los	los	PROPN
fnp-3050	908	21	santos	santos	PROPN
fnp-3050	908	22	mb	mb	PROPN
fnp-3050	908	23	,	,	PUNCT
fnp-3050	908	24	klickstein	klickstein	PROPN
fnp-3050	908	25	n	n	CCONJ
fnp-3050	908	26	,	,	PUNCT
fnp-3050	908	27	corjuc	corjuc	VERB
fnp-3050	908	28	dl	dl	PROPN
fnp-3050	908	29	,	,	PUNCT
fnp-3050	908	30	corjuc	corjuc	VERB
fnp-3050	908	31	bt	bt	PROPN
fnp-3050	908	32	,	,	PUNCT
fnp-3050	908	33	dooley	dooley	NOUN
fnp-3050	908	34	pm	pm	PROPN
fnp-3050	908	35	,	,	PUNCT
fnp-3050	908	36	viode	viode	VERB
fnp-3050	908	37	a	a	PRON
fnp-3050	908	38	,	,	PUNCT
fnp-3050	908	39	oakley	oakley	PROPN
fnp-3050	908	40	dh	dh	PROPN
fnp-3050	908	41	,	,	PUNCT
fnp-3050	908	42	moore	moore	PROPN
fnp-3050	908	43	bd	bd	PROPN
fnp-3050	908	44	,	,	PUNCT
fnp-3050	908	45	mullin	mullin	PROPN
fnp-3050	908	46	k	k	PROPN
fnp-3050	908	47	,	,	PUNCT
fnp-3050	908	48	jean	jean	PROPN
fnp-3050	908	49	-	-	PUNCT
fnp-3050	908	50	gilles	gilles	PROPN
fnp-3050	908	51	d	d	PROPN
fnp-3050	908	52	,	,	PUNCT
fnp-3050	908	53	clark	clark	PROPN
fnp-3050	908	54	r	r	PROPN
fnp-3050	908	55	,	,	PUNCT
fnp-3050	908	56	atchison	atchison	PROPN
fnp-3050	908	57	k	k	PROPN
fnp-3050	908	58	,	,	PUNCT
fnp-3050	908	59	moore	moore	PROPN
fnp-3050	908	60	r	r	PROPN
fnp-3050	908	61	,	,	PUNCT
fnp-3050	908	62	chibnik	chibnik	NOUN
fnp-3050	908	63	lb	lb	NUM
fnp-3050	908	64	,	,	PUNCT
fnp-3050	908	65	tanzi	tanzi	X
fnp-3050	908	66	re	re	PROPN
fnp-3050	908	67	,	,	PUNCT
fnp-3050	908	68	frosch	frosch	PROPN
fnp-3050	908	69	mp	mp	PROPN
fnp-3050	908	70	,	,	PUNCT
fnp-3050	908	71	serrano	serrano	PROPN
fnp-3050	908	72	-	-	PUNCT
fnp-3050	908	73	pozo	pozo	PROPN
fnp-3050	908	74	a	a	PROPN
fnp-3050	908	75	,	,	PUNCT
fnp-3050	908	76	elwood	elwood	PROPN
fnp-3050	908	77	f	f	PROPN
fnp-3050	908	78	,	,	PUNCT
fnp-3050	908	79	steen	steen	PROPN
fnp-3050	908	80	ja	ja	PROPN
fnp-3050	908	81	,	,	PUNCT
fnp-3050	908	82	kennedy	kennedy	PROPN
fnp-3050	908	83	me	me	PROPN
fnp-3050	908	84	,	,	PUNCT
fnp-3050	908	85	hyman	hyman	PROPN
fnp-3050	908	86	bt	bt	PROPN
fnp-3050	908	87	(	(	PUNCT
fnp-3050	908	88	2020	2020	NUM
fnp-3050	908	89	)	)	PUNCT
fnp-3050	908	90	tau	tau	PROPN
fnp-3050	908	91	molecular	molecular	ADJ
fnp-3050	908	92	diversity	diversity	NOUN
fnp-3050	908	93	contributes	contribute	VERB
fnp-3050	908	94	to	to	ADP
fnp-3050	908	95	clinical	clinical	ADJ
fnp-3050	908	96	heterogeneity	heterogeneity	NOUN
fnp-3050	908	97	in	in	ADP
fnp-3050	908	98	alzheimer	alzheimer	PROPN
fnp-3050	908	99	's	's	PART
fnp-3050	908	100	disease	disease	NOUN
fnp-3050	908	101	.	.	PUNCT
fnp-3050	909	1	nat	nat	PROPN
fnp-3050	909	2	med	me	VERB
fnp-3050	909	3	26:1256	26:1256	PROPN
fnp-3050	909	4	-	-	PROPN
fnp-3050	909	5	1263	1263	NUM
fnp-3050	909	6	193	193	NUM
fnp-3050	909	7	.	.	PUNCT
fnp-3050	910	1	sintini	sintini	PROPN
fnp-3050	910	2	i	i	PROPN
fnp-3050	910	3	,	,	PUNCT
fnp-3050	910	4	graff	graff	PROPN
fnp-3050	910	5	-	-	PUNCT
fnp-3050	910	6	radford	radford	PROPN
fnp-3050	910	7	j	j	PROPN
fnp-3050	910	8	,	,	PUNCT
fnp-3050	910	9	senjem	senjem	VERB
fnp-3050	910	10	ml	ml	ADP
fnp-3050	910	11	,	,	PUNCT
fnp-3050	910	12	schwarz	schwarz	PROPN
fnp-3050	910	13	cg	cg	PROPN
fnp-3050	910	14	,	,	PUNCT
fnp-3050	910	15	machulda	machulda	NOUN
fnp-3050	910	16	mm	mm	PROPN
fnp-3050	910	17	,	,	PUNCT
fnp-3050	910	18	martin	martin	PROPN
fnp-3050	910	19	pr	pr	PROPN
fnp-3050	910	20	,	,	PUNCT
fnp-3050	910	21	jones	jones	PROPN
fnp-3050	910	22	dt	dt	PROPN
fnp-3050	910	23	,	,	PUNCT
fnp-3050	910	24	boeve	boeve	NOUN
fnp-3050	910	25	bf	bf	NOUN
fnp-3050	910	26	,	,	PUNCT
fnp-3050	910	27	knopman	knopman	NOUN
fnp-3050	910	28	ds	ds	PROPN
fnp-3050	910	29	,	,	PUNCT
fnp-3050	910	30	kantarci	kantarci	PROPN
fnp-3050	910	31	k	k	PROPN
fnp-3050	910	32	,	,	PUNCT
fnp-3050	910	33	petersen	petersen	PROPN
fnp-3050	910	34	rc	rc	PROPN
fnp-3050	910	35	,	,	PUNCT
fnp-3050	910	36	jack	jack	PROPN
fnp-3050	910	37	cr	cr	PROPN
fnp-3050	910	38	,	,	PUNCT
fnp-3050	910	39	lowe	lowe	PROPN
fnp-3050	910	40	vj	vj	PROPN
fnp-3050	910	41	,	,	PUNCT
fnp-3050	910	42	josephs	josephs	PROPN
fnp-3050	910	43	ka	ka	PROPN
fnp-3050	910	44	,	,	PUNCT
fnp-3050	910	45	whitwell	whitwell	INTJ
fnp-3050	910	46	jl	jl	X
fnp-3050	910	47	(	(	PUNCT
fnp-3050	910	48	2020	2020	NUM
fnp-3050	910	49	)	)	PUNCT
fnp-3050	910	50	longitudinal	longitudinal	ADJ
fnp-3050	910	51	neuroimaging	neuroimage	VERB
fnp-3050	910	52	biomarkers	biomarker	NOUN
fnp-3050	910	53	differ	differ	VERB
fnp-3050	910	54	across	across	ADP
fnp-3050	910	55	alzheimer	alzheimer	PROPN
fnp-3050	910	56	's	's	PART
fnp-3050	910	57	disease	disease	NOUN
fnp-3050	910	58	phenotypes	phenotype	NOUN
fnp-3050	910	59	.	.	PUNCT
fnp-3050	911	1	brain	brain	NOUN
fnp-3050	911	2	143:2281	143:2281	PROPN
fnp-3050	911	3	-	-	SYM
fnp-3050	911	4	2294	2294	NUM
fnp-3050	911	5	194	194	NUM
fnp-3050	911	6	.	.	PUNCT
fnp-3050	912	1	pascoal	pascoal	PROPN
fnp-3050	912	2	ta	ta	PROPN
fnp-3050	912	3	,	,	PUNCT
fnp-3050	912	4	mathotaarachchi	mathotaarachchi	PROPN
fnp-3050	912	5	s	s	NOUN
fnp-3050	912	6	,	,	PUNCT
fnp-3050	912	7	shin	shin	PROPN
fnp-3050	912	8	m	m	PROPN
fnp-3050	912	9	,	,	PUNCT
fnp-3050	912	10	benedet	benedet	PROPN
fnp-3050	912	11	al	al	PROPN
fnp-3050	912	12	,	,	PUNCT
fnp-3050	912	13	mohades	mohade	NOUN
fnp-3050	912	14	s	s	PART
fnp-3050	912	15	,	,	PUNCT
fnp-3050	912	16	wang	wang	PROPN
fnp-3050	912	17	s	s	PROPN
fnp-3050	912	18	,	,	PUNCT
fnp-3050	912	19	beaudry	beaudry	PROPN
fnp-3050	912	20	t	t	PROPN
fnp-3050	912	21	,	,	PUNCT
fnp-3050	912	22	kang	kang	PROPN
fnp-3050	912	23	ms	ms	PROPN
fnp-3050	912	24	,	,	PUNCT
fnp-3050	912	25	soucy	soucy	PROPN
fnp-3050	912	26	jp	jp	NOUN
fnp-3050	912	27	,	,	PUNCT
fnp-3050	912	28	labbe	labbe	X
fnp-3050	912	29	a	a	X
fnp-3050	912	30	,	,	PUNCT
fnp-3050	912	31	gauthier	gauthier	PROPN
fnp-3050	912	32	s	s	PROPN
fnp-3050	912	33	,	,	PUNCT
fnp-3050	912	34	rosa	rosa	PROPN
fnp-3050	912	35	-	-	PUNCT
fnp-3050	912	36	neto	neto	PROPN
fnp-3050	912	37	p	p	PROPN
fnp-3050	912	38	(	(	PUNCT
fnp-3050	912	39	2017	2017	NUM
fnp-3050	912	40	)	)	PUNCT
fnp-3050	912	41	synergistic	synergistic	ADJ
fnp-3050	912	42	interaction	interaction	NOUN
fnp-3050	912	43	between	between	ADP
fnp-3050	912	44	amyloid	amyloid	NOUN
fnp-3050	912	45	and	and	CCONJ
fnp-3050	912	46	tau	tau	PROPN
fnp-3050	912	47	predicts	predict	VERB
fnp-3050	912	48	the	the	DET
fnp-3050	912	49	progression	progression	NOUN
fnp-3050	912	50	to	to	ADP
fnp-3050	912	51	dementia	dementia	PROPN
fnp-3050	912	52	.	.	PUNCT
fnp-3050	913	1	alzheimers	alzheimers	PROPN
fnp-3050	913	2	dement	dement	PROPN
fnp-3050	913	3	13:644	13:644	NUM
fnp-3050	913	4	-	-	SYM
fnp-3050	913	5	653	653	NUM
fnp-3050	913	6	195	195	NUM
fnp-3050	913	7	.	.	PUNCT
fnp-3050	914	1	thal	thal	PROPN
fnp-3050	914	2	dr	dr	PROPN
fnp-3050	914	3	,	,	PUNCT
fnp-3050	914	4	griffin	griffin	PROPN
fnp-3050	914	5	ws	ws	PROPN
fnp-3050	914	6	,	,	PUNCT
fnp-3050	914	7	braak	braak	PROPN
fnp-3050	914	8	h	h	PROPN
fnp-3050	914	9	(	(	PUNCT
fnp-3050	914	10	2008	2008	NUM
fnp-3050	914	11	)	)	PUNCT
fnp-3050	914	12	parenchymal	parenchymal	ADJ
fnp-3050	914	13	and	and	CCONJ
fnp-3050	914	14	vascular	vascular	ADJ
fnp-3050	914	15	abeta	abeta	ADJ
fnp-3050	914	16	-	-	PUNCT
fnp-3050	914	17	deposition	deposition	NOUN
fnp-3050	914	18	and	and	CCONJ
fnp-3050	914	19	its	its	PRON
fnp-3050	914	20	effects	effect	NOUN
fnp-3050	914	21	on	on	ADP
fnp-3050	914	22	the	the	DET
fnp-3050	914	23	degeneration	degeneration	NOUN
fnp-3050	914	24	of	of	ADP
fnp-3050	914	25	neurons	neuron	NOUN
fnp-3050	914	26	and	and	CCONJ
fnp-3050	914	27	cognition	cognition	NOUN
fnp-3050	914	28	in	in	ADP
fnp-3050	914	29	alzheimer	alzheimer	PROPN
fnp-3050	914	30	's	's	PART
fnp-3050	914	31	disease	disease	NOUN
fnp-3050	914	32	.	.	PUNCT
fnp-3050	915	1	j	j	PROPN
fnp-3050	915	2	cell	cell	PROPN
fnp-3050	915	3	mol	mol	ADP
fnp-3050	915	4	med	med	PROPN
fnp-3050	915	5	12:1848	12:1848	PROPN
fnp-3050	915	6	-	-	SYM
fnp-3050	915	7	1862	1862	NUM
fnp-3050	915	8	196	196	NUM
fnp-3050	915	9	.	.	PUNCT
fnp-3050	916	1	gomez	gomez	PROPN
fnp-3050	916	2	-	-	PUNCT
fnp-3050	916	3	isla	isla	PROPN
fnp-3050	916	4	t	t	PROPN
fnp-3050	916	5	,	,	PUNCT
fnp-3050	916	6	hollister	hollister	PROPN
fnp-3050	916	7	r	r	PROPN
fnp-3050	916	8	,	,	PUNCT
fnp-3050	916	9	west	west	ADJ
fnp-3050	916	10	h	h	NOUN
fnp-3050	916	11	,	,	PUNCT
fnp-3050	916	12	mui	mui	PROPN
fnp-3050	916	13	s	s	PROPN
fnp-3050	916	14	,	,	PUNCT
fnp-3050	916	15	growdon	growdon	VERB
fnp-3050	916	16	jh	jh	PROPN
fnp-3050	916	17	,	,	PUNCT
fnp-3050	916	18	petersen	petersen	PROPN
fnp-3050	916	19	rc	rc	PROPN
fnp-3050	916	20	,	,	PUNCT
fnp-3050	916	21	parisi	parisi	PROPN
fnp-3050	916	22	je	je	PROPN
fnp-3050	916	23	,	,	PUNCT
fnp-3050	916	24	hyman	hyman	PROPN
fnp-3050	916	25	bt	bt	PROPN
fnp-3050	916	26	(	(	PUNCT
fnp-3050	916	27	1997	1997	NUM
fnp-3050	916	28	)	)	PUNCT
fnp-3050	916	29	neuronal	neuronal	ADJ
fnp-3050	916	30	loss	loss	NOUN
fnp-3050	916	31	correlates	correlate	VERB
fnp-3050	916	32	with	with	ADP
fnp-3050	916	33	but	but	CCONJ
fnp-3050	916	34	exceeds	exceed	VERB
fnp-3050	916	35	neurofibrillary	neurofibrillary	ADJ
fnp-3050	916	36	tangles	tangle	NOUN
fnp-3050	916	37	in	in	ADP
fnp-3050	916	38	alzheimer	alzheimer	PROPN
fnp-3050	916	39	's	's	PART
fnp-3050	916	40	disease	disease	NOUN
fnp-3050	916	41	.	.	PUNCT
fnp-3050	917	1	ann	ann	PROPN
fnp-3050	917	2	neurol	neurol	PROPN
fnp-3050	917	3	41:17	41:17	NUM
fnp-3050	917	4	-	-	SYM
fnp-3050	917	5	24	24	NUM
fnp-3050	917	6	197	197	NUM
fnp-3050	917	7	.	.	PUNCT
fnp-3050	918	1	saez	saez	PROPN
fnp-3050	918	2	-	-	PUNCT
fnp-3050	918	3	atienzar	atienzar	PROPN
fnp-3050	918	4	s	s	NOUN
fnp-3050	918	5	,	,	PUNCT
fnp-3050	918	6	masliah	masliah	PROPN
fnp-3050	918	7	e	e	PROPN
fnp-3050	918	8	(	(	PUNCT
fnp-3050	918	9	2020	2020	NUM
fnp-3050	918	10	)	)	PUNCT
fnp-3050	918	11	cellular	cellular	ADJ
fnp-3050	918	12	senescence	senescence	NOUN
fnp-3050	918	13	and	and	CCONJ
fnp-3050	918	14	alzheimer	alzheimer	PROPN
fnp-3050	918	15	disease	disease	PROPN
fnp-3050	918	16	:	:	PUNCT
fnp-3050	918	17	the	the	DET
fnp-3050	918	18	egg	egg	NOUN
fnp-3050	918	19	and	and	CCONJ
fnp-3050	918	20	the	the	DET
fnp-3050	918	21	chicken	chicken	NOUN
fnp-3050	918	22	scenario	scenario	NOUN
fnp-3050	918	23	.	.	PUNCT
fnp-3050	919	1	nat	nat	PROPN
fnp-3050	919	2	rev	rev	PROPN
fnp-3050	919	3	neurosci	neurosci	PROPN
fnp-3050	919	4	21:433	21:433	PROPN
fnp-3050	919	5	-	-	SYM
fnp-3050	919	6	444	444	NUM
fnp-3050	919	7	198	198	NUM
fnp-3050	919	8	.	.	PUNCT
fnp-3050	920	1	brewer	brewer	PROPN
fnp-3050	920	2	gj	gj	PROPN
fnp-3050	920	3	,	,	PUNCT
fnp-3050	920	4	herrera	herrera	PROPN
fnp-3050	920	5	ra	ra	PROPN
fnp-3050	920	6	,	,	PUNCT
fnp-3050	920	7	philipp	philipp	PROPN
fnp-3050	920	8	s	s	PROPN
fnp-3050	920	9	,	,	PUNCT
fnp-3050	920	10	sosna	sosna	PROPN
fnp-3050	920	11	j	j	PROPN
fnp-3050	920	12	,	,	PUNCT
fnp-3050	920	13	reyes	reyes	PROPN
fnp-3050	920	14	-	-	PUNCT
fnp-3050	920	15	ruiz	ruiz	PROPN
fnp-3050	920	16	jm	jm	PROPN
fnp-3050	920	17	,	,	PUNCT
fnp-3050	920	18	glabe	glabe	PROPN
fnp-3050	920	19	cg	cg	NOUN
fnp-3050	920	20	(	(	PUNCT
fnp-3050	920	21	2020	2020	NUM
fnp-3050	920	22	)	)	PUNCT
fnp-3050	920	23	age	age	NOUN
fnp-3050	920	24	-	-	PUNCT
fnp-3050	920	25	related	relate	VERB
fnp-3050	920	26	intraneuronal	intraneuronal	ADJ
fnp-3050	920	27	aggregation	aggregation	NOUN
fnp-3050	920	28	of	of	ADP
fnp-3050	920	29	amyloid	amyloid	NOUN
fnp-3050	920	30	-	-	PUNCT
fnp-3050	920	31	beta	beta	NOUN
fnp-3050	920	32	in	in	ADP
fnp-3050	920	33	endosomes	endosome	NOUN
fnp-3050	920	34	,	,	PUNCT
fnp-3050	920	35	mitochondria	mitochondria	PROPN
fnp-3050	920	36	,	,	PUNCT
fnp-3050	920	37	autophagosomes	autophagosome	NOUN
fnp-3050	920	38	,	,	PUNCT
fnp-3050	920	39	and	and	CCONJ
fnp-3050	920	40	lysosomes	lysosome	NOUN
fnp-3050	920	41	.	.	PUNCT
fnp-3050	921	1	j	j	PROPN
fnp-3050	921	2	alzheimers	alzheimers	PROPN
fnp-3050	921	3	dis	dis	PROPN
fnp-3050	921	4	73:229	73:229	NUM
fnp-3050	921	5	-	-	SYM
fnp-3050	921	6	246	246	NUM
fnp-3050	921	7	199	199	NUM
fnp-3050	921	8	.	.	PUNCT
fnp-3050	922	1	llorian	llorian	PROPN
fnp-3050	922	2	m	m	PROPN
fnp-3050	922	3	,	,	PUNCT
fnp-3050	922	4	schwartz	schwartz	PROPN
fnp-3050	922	5	s	s	PROPN
fnp-3050	922	6	,	,	PUNCT
fnp-3050	922	7	clark	clark	PROPN
fnp-3050	922	8	ta	ta	PROPN
fnp-3050	922	9	,	,	PUNCT
fnp-3050	922	10	hollander	hollander	PROPN
fnp-3050	922	11	d	d	PROPN
fnp-3050	922	12	,	,	PUNCT
fnp-3050	922	13	tan	tan	PROPN
fnp-3050	922	14	ly	ly	PROPN
fnp-3050	922	15	,	,	PUNCT
fnp-3050	922	16	spellman	spellman	PROPN
fnp-3050	922	17	r	r	PROPN
fnp-3050	922	18	,	,	PUNCT
fnp-3050	922	19	gordon	gordon	PROPN
fnp-3050	922	20	a	a	PRON
fnp-3050	922	21	,	,	PUNCT
fnp-3050	922	22	schweitzer	schweitzer	PROPN
fnp-3050	922	23	ac	ac	PROPN
fnp-3050	922	24	,	,	PUNCT
fnp-3050	922	25	de	de	PROPN
fnp-3050	922	26	la	la	PROPN
fnp-3050	922	27	grange	grange	PROPN
fnp-3050	922	28	p	p	PROPN
fnp-3050	922	29	,	,	PUNCT
fnp-3050	922	30	ast	ast	NOUN
fnp-3050	922	31	g	g	NOUN
fnp-3050	922	32	,	,	PUNCT
fnp-3050	922	33	smith	smith	PROPN
fnp-3050	922	34	cw	cw	PROPN
fnp-3050	922	35	(	(	PUNCT
fnp-3050	922	36	2010	2010	NUM
fnp-3050	922	37	)	)	PUNCT
fnp-3050	922	38	position	position	NOUN
fnp-3050	922	39	-	-	PUNCT
fnp-3050	922	40	dependent	dependent	ADJ
fnp-3050	922	41	alternative	alternative	ADJ
fnp-3050	922	42	splicing	splicing	NOUN
fnp-3050	922	43	activity	activity	NOUN
fnp-3050	922	44	revealed	reveal	VERB
fnp-3050	922	45	by	by	ADP
fnp-3050	922	46	global	global	ADJ
fnp-3050	922	47	profiling	profiling	NOUN
fnp-3050	922	48	of	of	ADP
fnp-3050	922	49	alternative	alternative	ADJ
fnp-3050	922	50	splicing	splicing	NOUN
fnp-3050	922	51	events	event	NOUN
fnp-3050	922	52	regulated	regulate	VERB
fnp-3050	922	53	by	by	ADP
fnp-3050	922	54	ptb	ptb	PROPN
fnp-3050	922	55	.	.	PUNCT
fnp-3050	923	1	nat	nat	PROPN
fnp-3050	923	2	struct	struct	NOUN
fnp-3050	923	3	mol	mol	ADP
fnp-3050	923	4	biol	biol	PROPN
fnp-3050	923	5	17:1114	17:1114	NOUN
fnp-3050	923	6	-	-	SYM
fnp-3050	923	7	1123	1123	NUM
fnp-3050	923	8	200	200	NUM
fnp-3050	923	9	.	.	PUNCT
fnp-3050	924	1	zanjani	zanjani	PROPN
fnp-3050	924	2	h	h	PROPN
fnp-3050	924	3	,	,	PUNCT
fnp-3050	924	4	finch	finch	PROPN
fnp-3050	924	5	ce	ce	PROPN
fnp-3050	924	6	,	,	PUNCT
fnp-3050	924	7	kemper	kemper	PROPN
fnp-3050	924	8	c	c	PROPN
fnp-3050	924	9	,	,	PUNCT
fnp-3050	924	10	atkinson	atkinson	PROPN
fnp-3050	924	11	j	j	PROPN
fnp-3050	924	12	,	,	PUNCT
fnp-3050	924	13	mckeel	mckeel	PROPN
fnp-3050	924	14	d	d	PROPN
fnp-3050	924	15	,	,	PUNCT
fnp-3050	924	16	morris	morris	PROPN
fnp-3050	924	17	jc	jc	PROPN
fnp-3050	924	18	,	,	PUNCT
fnp-3050	924	19	price	price	NOUN
fnp-3050	924	20	jl	jl	NOUN
fnp-3050	924	21	(	(	PUNCT
fnp-3050	924	22	2005	2005	NUM
fnp-3050	924	23	)	)	PUNCT
fnp-3050	924	24	complement	complement	NOUN
fnp-3050	924	25	activation	activation	NOUN
fnp-3050	924	26	in	in	ADP
fnp-3050	924	27	very	very	ADV
fnp-3050	924	28	early	early	ADJ
fnp-3050	924	29	alzheimer	alzheimer	PROPN
fnp-3050	924	30	disease	disease	NOUN
fnp-3050	924	31	.	.	PUNCT
fnp-3050	925	1	alzheimer	alzheimer	PROPN
fnp-3050	925	2	dis	dis	PROPN
fnp-3050	925	3	assoc	assoc	PROPN
fnp-3050	925	4	disord	disord	PROPN
fnp-3050	925	5	19:55	19:55	NUM
fnp-3050	925	6	-	-	SYM
fnp-3050	925	7	66	66	NUM
fnp-3050	925	8	201	201	NUM
fnp-3050	925	9	.	.	PUNCT
fnp-3050	926	1	kordower	kordower	PROPN
fnp-3050	926	2	jh	jh	PROPN
fnp-3050	926	3	,	,	PUNCT
fnp-3050	926	4	chu	chu	PROPN
fnp-3050	926	5	y	y	PROPN
fnp-3050	926	6	,	,	PUNCT
fnp-3050	926	7	stebbins	stebbins	PROPN
fnp-3050	926	8	gt	gt	PROPN
fnp-3050	926	9	,	,	PUNCT
fnp-3050	926	10	dekosky	dekosky	PROPN
fnp-3050	926	11	st	st	PROPN
fnp-3050	926	12	,	,	PUNCT
fnp-3050	926	13	cochran	cochran	PROPN
fnp-3050	926	14	ej	ej	PROPN
fnp-3050	926	15	,	,	PUNCT
fnp-3050	926	16	bennett	bennett	PROPN
fnp-3050	926	17	d	d	PROPN
fnp-3050	926	18	,	,	PUNCT
fnp-3050	926	19	mufson	mufson	NOUN
fnp-3050	926	20	ej	ej	X
fnp-3050	926	21	(	(	PUNCT
fnp-3050	926	22	2001	2001	NUM
fnp-3050	926	23	)	)	PUNCT
fnp-3050	926	24	loss	loss	NOUN
fnp-3050	926	25	and	and	CCONJ
fnp-3050	926	26	atrophy	atrophy	NOUN
fnp-3050	926	27	of	of	ADP
fnp-3050	926	28	layer	layer	NOUN
fnp-3050	926	29	ii	ii	PROPN
fnp-3050	926	30	entorhinal	entorhinal	ADJ
fnp-3050	926	31	cortex	cortex	NOUN
fnp-3050	926	32	neurons	neuron	NOUN
fnp-3050	926	33	in	in	ADP
fnp-3050	926	34	elderly	elderly	ADJ
fnp-3050	926	35	people	people	NOUN
fnp-3050	926	36	with	with	ADP
fnp-3050	926	37	mild	mild	ADJ
fnp-3050	926	38	cognitive	cognitive	ADJ
fnp-3050	926	39	impairment	impairment	NOUN
fnp-3050	926	40	.	.	PUNCT
fnp-3050	927	1	ann	ann	PROPN
fnp-3050	927	2	neurol	neurol	PROPN
fnp-3050	927	3	49:202	49:202	PROPN
fnp-3050	927	4	-	-	PUNCT
fnp-3050	927	5	213	213	NUM
fnp-3050	927	6	202	202	NUM
fnp-3050	927	7	.	.	PUNCT
fnp-3050	928	1	duyckaerts	duyckaert	NOUN
fnp-3050	928	2	c	c	PROPN
fnp-3050	928	3	(	(	PUNCT
fnp-3050	928	4	2014	2014	NUM
fnp-3050	928	5	)	)	PUNCT
fnp-3050	928	6	alzheimer	alzheimer	PROPN
fnp-3050	928	7	’s	’s	PART
fnp-3050	928	8	disease	disease	NOUN
fnp-3050	928	9	.	.	PUNCT
fnp-3050	929	1	in	in	ADP
fnp-3050	929	2	:	:	PUNCT
fnp-3050	929	3	kovacs	kovacs	PROPN
fnp-3050	929	4	gg	gg	PROPN
fnp-3050	929	5	(	(	PUNCT
fnp-3050	929	6	ed	ed	NOUN
fnp-3050	929	7	)	)	PUNCT
fnp-3050	929	8	neuropathology	neuropathology	NOUN
fnp-3050	929	9	of	of	ADP
fnp-3050	929	10	neurodegenerative	neurodegenerative	ADJ
fnp-3050	929	11	diseases	disease	NOUN
fnp-3050	929	12	.	.	PUNCT
fnp-3050	930	1	a	a	DET
fnp-3050	930	2	practical	practical	ADJ
fnp-3050	930	3	guide	guide	NOUN
fnp-3050	930	4	.	.	PUNCT
fnp-3050	931	1	cambridge	cambridge	PROPN
fnp-3050	931	2	university	university	PROPN
fnp-3050	931	3	press	press	PROPN
fnp-3050	931	4	cambridge	cambridge	PROPN
fnp-3050	931	5	,	,	PUNCT
fnp-3050	931	6	pp	pp	ADV
fnp-3050	931	7	80	80	NUM
fnp-3050	931	8	-	-	SYM
fnp-3050	931	9	108	108	NUM
fnp-3050	931	10	203	203	NUM
fnp-3050	931	11	.	.	PUNCT
fnp-3050	932	1	jellinger	jellinger	PROPN
fnp-3050	932	2	ka	ka	PROPN
fnp-3050	932	3	(	(	PUNCT
fnp-3050	932	4	2006	2006	NUM
fnp-3050	932	5	)	)	PUNCT
fnp-3050	932	6	challenges	challenge	NOUN
fnp-3050	932	7	in	in	ADP
fnp-3050	932	8	neuronal	neuronal	ADJ
fnp-3050	932	9	apoptosis	apoptosis	NOUN
fnp-3050	932	10	.	.	PUNCT
fnp-3050	933	1	curr	curr	PROPN
fnp-3050	933	2	alzheimer	alzheimer	PROPN
fnp-3050	933	3	res	res	PROPN
fnp-3050	933	4	3:377	3:377	PROPN
fnp-3050	933	5	-	-	SYM
fnp-3050	933	6	391	391	NUM
fnp-3050	933	7	204	204	NUM
fnp-3050	933	8	.	.	PUNCT
fnp-3050	934	1	woodhouse	woodhouse	PROPN
fnp-3050	934	2	a	a	PROPN
fnp-3050	934	3	,	,	PUNCT
fnp-3050	934	4	dickson	dickson	PROPN
fnp-3050	934	5	tc	tc	PROPN
fnp-3050	934	6	,	,	PUNCT
fnp-3050	934	7	west	west	PROPN
fnp-3050	934	8	ak	ak	PROPN
fnp-3050	934	9	,	,	PUNCT
fnp-3050	934	10	mclean	mclean	PROPN
fnp-3050	934	11	ca	ca	PROPN
fnp-3050	934	12	,	,	PUNCT
fnp-3050	934	13	vickers	vickers	PROPN
fnp-3050	934	14	jc	jc	PROPN
fnp-3050	934	15	(	(	PUNCT
fnp-3050	934	16	2006	2006	NUM
fnp-3050	934	17	)	)	PUNCT
fnp-3050	934	18	no	no	DET
fnp-3050	934	19	difference	difference	NOUN
fnp-3050	934	20	in	in	ADP
fnp-3050	934	21	expression	expression	NOUN
fnp-3050	934	22	of	of	ADP
fnp-3050	934	23	apoptosis	apoptosis	NOUN
fnp-3050	934	24	-	-	PUNCT
fnp-3050	934	25	related	relate	VERB
fnp-3050	934	26	proteins	protein	NOUN
fnp-3050	934	27	and	and	CCONJ
fnp-3050	934	28	apoptotic	apoptotic	ADJ
fnp-3050	934	29	morphology	morphology	NOUN
fnp-3050	934	30	in	in	ADP
fnp-3050	934	31	control	control	NOUN
fnp-3050	934	32	,	,	PUNCT
fnp-3050	934	33	pathologically	pathologically	ADV
fnp-3050	934	34	aged	aged	ADJ
fnp-3050	934	35	and	and	CCONJ
fnp-3050	934	36	alzheimer	alzheimer	PROPN
fnp-3050	934	37	's	's	PART
fnp-3050	934	38	disease	disease	NOUN
fnp-3050	934	39	cases	case	NOUN
fnp-3050	934	40	.	.	PUNCT
fnp-3050	935	1	neurobiol	neurobiol	PROPN
fnp-3050	935	2	dis	dis	PROPN
fnp-3050	935	3	22:323	22:323	NUM
fnp-3050	935	4	-	-	SYM
fnp-3050	935	5	333	333	NUM
fnp-3050	935	6	205	205	NUM
fnp-3050	935	7	.	.	PUNCT
fnp-3050	936	1	gorlovoy	gorlovoy	PROPN
fnp-3050	936	2	p	p	NOUN
fnp-3050	936	3	,	,	PUNCT
fnp-3050	936	4	larionov	larionov	PROPN
fnp-3050	936	5	s	s	PROPN
fnp-3050	936	6	,	,	PUNCT
fnp-3050	936	7	pham	pham	PROPN
fnp-3050	936	8	tt	tt	PROPN
fnp-3050	936	9	,	,	PUNCT
fnp-3050	936	10	neumann	neumann	PROPN
fnp-3050	936	11	h	h	PROPN
fnp-3050	936	12	(	(	PUNCT
fnp-3050	936	13	2009	2009	NUM
fnp-3050	936	14	)	)	PUNCT
fnp-3050	936	15	accumulation	accumulation	NOUN
fnp-3050	936	16	of	of	ADP
fnp-3050	936	17	tau	tau	PROPN
fnp-3050	936	18	induced	induce	VERB
fnp-3050	936	19	in	in	ADP
fnp-3050	936	20	neurites	neurite	NOUN
fnp-3050	936	21	by	by	ADP
fnp-3050	936	22	microglial	microglial	ADJ
fnp-3050	936	23	proinflammatory	proinflammatory	ADJ
fnp-3050	936	24	mediators	mediator	NOUN
fnp-3050	936	25	.	.	PUNCT
fnp-3050	937	1	faseb	faseb	PROPN
fnp-3050	937	2	j	j	PROPN
fnp-3050	937	3	23:2502	23:2502	X
fnp-3050	937	4	-	-	SYM
fnp-3050	937	5	2513	2513	NUM
fnp-3050	937	6	206	206	NUM
fnp-3050	937	7	.	.	PUNCT
fnp-3050	938	1	li	li	PROPN
fnp-3050	938	2	jw	jw	PROPN
fnp-3050	938	3	,	,	PUNCT
fnp-3050	938	4	zong	zong	PROPN
fnp-3050	938	5	y	y	PROPN
fnp-3050	938	6	,	,	PUNCT
fnp-3050	938	7	cao	cao	PROPN
fnp-3050	938	8	xp	xp	PROPN
fnp-3050	938	9	,	,	PUNCT
fnp-3050	938	10	tan	tan	PROPN
fnp-3050	938	11	l	l	PROPN
fnp-3050	938	12	(	(	PUNCT
fnp-3050	938	13	2018	2018	NUM
fnp-3050	938	14	)	)	PUNCT
fnp-3050	938	15	microglial	microglial	ADJ
fnp-3050	938	16	priming	priming	NOUN
fnp-3050	938	17	in	in	ADP
fnp-3050	938	18	alzheimer	alzheimer	PROPN
fnp-3050	938	19	's	's	PART
fnp-3050	938	20	disease	disease	NOUN
fnp-3050	938	21	.	.	PUNCT
fnp-3050	939	1	ann	ann	PROPN
fnp-3050	939	2	transl	transl	PROPN
fnp-3050	939	3	med	me	VERB
fnp-3050	939	4	6:176	6:176	NUM
fnp-3050	939	5	207	207	NUM
fnp-3050	939	6	.	.	PUNCT
fnp-3050	940	1	forner	forner	PROPN
fnp-3050	940	2	s	s	PART
fnp-3050	940	3	,	,	PUNCT
fnp-3050	940	4	baglietto	baglietto	NOUN
fnp-3050	940	5	-	-	PUNCT
fnp-3050	940	6	vargas	vargas	PROPN
fnp-3050	940	7	d	d	NOUN
fnp-3050	940	8	,	,	PUNCT
fnp-3050	940	9	martini	martini	PROPN
fnp-3050	940	10	ac	ac	PROPN
fnp-3050	940	11	,	,	PUNCT
fnp-3050	940	12	trujillo	trujillo	PROPN
fnp-3050	940	13	-	-	PUNCT
fnp-3050	940	14	estrada	estrada	PROPN
fnp-3050	940	15	l	l	PROPN
fnp-3050	940	16	,	,	PUNCT
fnp-3050	940	17	laferla	laferla	PROPN
fnp-3050	940	18	fm	fm	PROPN
fnp-3050	940	19	(	(	PUNCT
fnp-3050	940	20	2017	2017	NUM
fnp-3050	940	21	)	)	PUNCT
fnp-3050	940	22	synaptic	synaptic	ADJ
fnp-3050	940	23	impairment	impairment	NOUN
fnp-3050	940	24	in	in	ADP
fnp-3050	940	25	alzheimer	alzheimer	PROPN
fnp-3050	940	26	's	's	PART
fnp-3050	940	27	disease	disease	NOUN
fnp-3050	940	28	:	:	PUNCT
fnp-3050	940	29	a	a	DET
fnp-3050	940	30	dysregulated	dysregulated	ADJ
fnp-3050	940	31	symphony	symphony	NOUN
fnp-3050	940	32	.	.	PUNCT
fnp-3050	941	1	trends	trend	NOUN
fnp-3050	941	2	neurosci	neurosci	VERB
fnp-3050	941	3	40:347	40:347	NUM
fnp-3050	941	4	-	-	SYM
fnp-3050	941	5	357	357	NUM
fnp-3050	941	6	208	208	NUM
fnp-3050	941	7	.	.	PUNCT
fnp-3050	942	1	scheff	scheff	PROPN
fnp-3050	942	2	sw	sw	PROPN
fnp-3050	942	3	,	,	PUNCT
fnp-3050	942	4	price	price	NOUN
fnp-3050	942	5	da	da	X
fnp-3050	942	6	(	(	PUNCT
fnp-3050	942	7	2003	2003	NUM
fnp-3050	942	8	)	)	PUNCT
fnp-3050	942	9	synaptic	synaptic	ADJ
fnp-3050	942	10	pathology	pathology	NOUN
fnp-3050	942	11	in	in	ADP
fnp-3050	942	12	alzheimer	alzheimer	PROPN
fnp-3050	942	13	's	's	PART
fnp-3050	942	14	disease	disease	NOUN
fnp-3050	942	15	:	:	PUNCT
fnp-3050	942	16	a	a	DET
fnp-3050	942	17	review	review	NOUN
fnp-3050	942	18	of	of	ADP
fnp-3050	942	19	ultrastructural	ultrastructural	ADJ
fnp-3050	942	20	studies	study	NOUN
fnp-3050	942	21	.	.	PUNCT
fnp-3050	943	1	neurobiol	neurobiol	PROPN
fnp-3050	943	2	aging	age	VERB
fnp-3050	943	3	24:1029	24:1029	NUM
fnp-3050	943	4	-	-	SYM
fnp-3050	943	5	1046	1046	NUM
fnp-3050	943	6	209	209	NUM
fnp-3050	943	7	.	.	PUNCT
fnp-3050	944	1	scheff	scheff	PROPN
fnp-3050	944	2	sw	sw	PROPN
fnp-3050	944	3	,	,	PUNCT
fnp-3050	944	4	price	price	NOUN
fnp-3050	944	5	da	da	NOUN
fnp-3050	944	6	,	,	PUNCT
fnp-3050	944	7	schmitt	schmitt	X
fnp-3050	944	8	fa	fa	PROPN
fnp-3050	944	9	,	,	PUNCT
fnp-3050	944	10	mufson	mufson	NOUN
fnp-3050	944	11	ej	ej	X
fnp-3050	944	12	(	(	PUNCT
fnp-3050	944	13	2006	2006	NUM
fnp-3050	944	14	)	)	PUNCT
fnp-3050	944	15	hippocampal	hippocampal	VERB
fnp-3050	944	16	synaptic	synaptic	ADJ
fnp-3050	944	17	loss	loss	NOUN
fnp-3050	944	18	in	in	ADP
fnp-3050	944	19	early	early	ADJ
fnp-3050	944	20	alzheimer	alzheimer	PROPN
fnp-3050	944	21	's	's	PART
fnp-3050	944	22	disease	disease	NOUN
fnp-3050	944	23	and	and	CCONJ
fnp-3050	944	24	mild	mild	ADJ
fnp-3050	944	25	cognitive	cognitive	ADJ
fnp-3050	944	26	impairment	impairment	NOUN
fnp-3050	944	27	.	.	PUNCT
fnp-3050	945	1	neurobiol	neurobiol	PROPN
fnp-3050	945	2	aging	age	VERB
fnp-3050	945	3	27:1372	27:1372	PROPN
fnp-3050	945	4	-	-	SYM
fnp-3050	945	5	1384	1384	NUM
fnp-3050	945	6	210	210	NUM
fnp-3050	945	7	.	.	PUNCT
fnp-3050	946	1	smith	smith	PROPN
fnp-3050	946	2	hl	hl	PROPN
fnp-3050	946	3	,	,	PUNCT
fnp-3050	946	4	freeman	freeman	PROPN
fnp-3050	946	5	oj	oj	PROPN
fnp-3050	946	6	,	,	PUNCT
fnp-3050	946	7	butcher	butcher	NOUN
fnp-3050	946	8	aj	aj	PROPN
fnp-3050	946	9	,	,	PUNCT
fnp-3050	946	10	holmqvist	holmqvist	PROPN
fnp-3050	946	11	s	s	PROPN
fnp-3050	946	12	,	,	PUNCT
fnp-3050	946	13	humoud	humoud	PROPN
fnp-3050	946	14	i	i	PROPN
fnp-3050	946	15	,	,	PUNCT
fnp-3050	946	16	schätzl	schätzl	PROPN
fnp-3050	946	17	t	t	PROPN
fnp-3050	946	18	,	,	PUNCT
fnp-3050	946	19	hughes	hughes	PROPN
fnp-3050	946	20	dt	dt	PROPN
fnp-3050	946	21	,	,	PUNCT
fnp-3050	946	22	verity	verity	PROPN
fnp-3050	946	23	nc	nc	PROPN
fnp-3050	946	24	,	,	PUNCT
fnp-3050	946	25	swinden	swinden	ADJ
fnp-3050	946	26	dp	dp	PROPN
fnp-3050	946	27	,	,	PUNCT
fnp-3050	946	28	hayes	hayes	PROPN
fnp-3050	946	29	j	j	PROPN
fnp-3050	946	30	,	,	PUNCT
fnp-3050	946	31	de	de	PROPN
fnp-3050	946	32	weerd	weerd	PROPN
fnp-3050	946	33	l	l	PROPN
fnp-3050	946	34	,	,	PUNCT
fnp-3050	946	35	rowitch	rowitch	VERB
fnp-3050	946	36	dh	dh	PROPN
fnp-3050	946	37	,	,	PUNCT
fnp-3050	946	38	franklin	franklin	PROPN
fnp-3050	946	39	rjm	rjm	PROPN
fnp-3050	946	40	,	,	PUNCT
fnp-3050	946	41	mallucci	mallucci	NOUN
fnp-3050	946	42	gr	gr	X
fnp-3050	946	43	(	(	PUNCT
fnp-3050	946	44	2020	2020	NUM
fnp-3050	946	45	)	)	PUNCT
fnp-3050	946	46	astrocyte	astrocyte	NOUN
fnp-3050	946	47	unfolded	unfold	VERB
fnp-3050	946	48	protein	protein	NOUN
fnp-3050	946	49	response	response	NOUN
fnp-3050	946	50	induces	induce	VERB
fnp-3050	946	51	a	a	DET
fnp-3050	946	52	specific	specific	ADJ
fnp-3050	946	53	reactivity	reactivity	NOUN
fnp-3050	946	54	state	state	NOUN
fnp-3050	946	55	that	that	PRON
fnp-3050	946	56	causes	cause	VERB
fnp-3050	946	57	non	non	ADJ
fnp-3050	946	58	-	-	ADJ
fnp-3050	946	59	cell	cell	ADJ
fnp-3050	946	60	-	-	PUNCT
fnp-3050	946	61	autonomous	autonomous	ADJ
fnp-3050	946	62	neuronal	neuronal	ADJ
fnp-3050	946	63	degeneration	degeneration	NOUN
fnp-3050	946	64	.	.	PUNCT
fnp-3050	947	1	neuron	neuron	PROPN
fnp-3050	947	2	105:855	105:855	PROPN
fnp-3050	947	3	-	-	PUNCT
fnp-3050	947	4	866	866	NUM
fnp-3050	948	1	e855	e855	NUM
fnp-3050	948	2	211	211	NUM
fnp-3050	948	3	.	.	PUNCT
fnp-3050	949	1	elliott	elliott	PROPN
fnp-3050	949	2	c	c	PROPN
fnp-3050	949	3	,	,	PUNCT
fnp-3050	949	4	rojo	rojo	PROPN
fnp-3050	949	5	ai	ai	NOUN
fnp-3050	949	6	,	,	PUNCT
fnp-3050	949	7	ribe	ribe	PROPN
fnp-3050	949	8	e	e	PROPN
fnp-3050	949	9	,	,	PUNCT
fnp-3050	949	10	broadstock	broadstock	NOUN
fnp-3050	949	11	m	m	PROPN
fnp-3050	949	12	,	,	PUNCT
fnp-3050	949	13	xia	xia	PROPN
fnp-3050	949	14	w	w	PROPN
fnp-3050	949	15	,	,	PUNCT
fnp-3050	949	16	morin	morin	PROPN
fnp-3050	949	17	p	p	NOUN
fnp-3050	949	18	,	,	PUNCT
fnp-3050	949	19	semenov	semenov	PROPN
fnp-3050	949	20	m	m	PROPN
fnp-3050	949	21	,	,	PUNCT
fnp-3050	949	22	baillie	baillie	PROPN
fnp-3050	949	23	g	g	PROPN
fnp-3050	949	24	,	,	PUNCT
fnp-3050	949	25	cuadrado	cuadrado	PROPN
fnp-3050	949	26	a	a	X
fnp-3050	949	27	,	,	PUNCT
fnp-3050	949	28	al	al	PROPN
fnp-3050	949	29	-	-	PUNCT
fnp-3050	949	30	shawi	shawi	NOUN
fnp-3050	949	31	r	r	NOUN
fnp-3050	949	32	,	,	PUNCT
fnp-3050	949	33	ballard	ballard	PROPN
fnp-3050	949	34	cg	cg	PROPN
fnp-3050	949	35	,	,	PUNCT
fnp-3050	949	36	simons	simon	NOUN
fnp-3050	949	37	p	p	X
fnp-3050	949	38	,	,	PUNCT
fnp-3050	949	39	killick	killick	NOUN
fnp-3050	949	40	r	r	NOUN
fnp-3050	949	41	(	(	PUNCT
fnp-3050	949	42	2018	2018	NUM
fnp-3050	949	43	)	)	PUNCT
fnp-3050	949	44	a	a	DET
fnp-3050	949	45	role	role	NOUN
fnp-3050	949	46	for	for	ADP
fnp-3050	949	47	app	app	NOUN
fnp-3050	949	48	in	in	ADP
fnp-3050	949	49	wnt	wnt	NOUN
fnp-3050	949	50	signalling	signal	VERB
fnp-3050	949	51	links	link	NOUN
fnp-3050	949	52	synapse	synapse	VERB
fnp-3050	949	53	loss	loss	NOUN
fnp-3050	949	54	with	with	ADP
fnp-3050	949	55	beta	beta	NOUN
fnp-3050	949	56	-	-	PUNCT
fnp-3050	949	57	amyloid	amyloid	NOUN
fnp-3050	949	58	production	production	NOUN
fnp-3050	949	59	.	.	PUNCT
fnp-3050	950	1	transl	transl	PROPN
fnp-3050	950	2	psychiatry	psychiatry	PROPN
fnp-3050	950	3	8:179	8:179	NUM
fnp-3050	950	4	212	212	NUM
fnp-3050	950	5	.	.	PUNCT
fnp-3050	951	1	marshall	marshall	PROPN
fnp-3050	951	2	ga	ga	PROPN
fnp-3050	951	3	,	,	PUNCT
fnp-3050	951	4	fairbanks	fairbanks	PROPN
fnp-3050	951	5	la	la	PROPN
fnp-3050	951	6	,	,	PUNCT
fnp-3050	951	7	tekin	tekin	PROPN
fnp-3050	951	8	s	s	NOUN
fnp-3050	951	9	,	,	PUNCT
fnp-3050	951	10	vinters	vinters	PROPN
fnp-3050	951	11	hv	hv	PROPN
fnp-3050	951	12	,	,	PUNCT
fnp-3050	951	13	cummings	cummings	PROPN
fnp-3050	951	14	jl	jl	PROPN
fnp-3050	951	15	(	(	PUNCT
fnp-3050	951	16	2007	2007	NUM
fnp-3050	951	17	)	)	PUNCT
fnp-3050	951	18	early	early	ADJ
fnp-3050	951	19	-	-	PUNCT
fnp-3050	951	20	onset	onset	NOUN
fnp-3050	951	21	alzheimer	alzheimer	NOUN
fnp-3050	951	22	's	's	PART
fnp-3050	951	23	disease	disease	NOUN
fnp-3050	951	24	is	be	AUX
fnp-3050	951	25	associated	associate	VERB
fnp-3050	951	26	with	with	ADP
fnp-3050	951	27	greater	great	ADJ
fnp-3050	951	28	pathologic	pathologic	ADJ
fnp-3050	951	29	burden	burden	NOUN
fnp-3050	951	30	.	.	PUNCT
fnp-3050	952	1	j	j	PROPN
fnp-3050	952	2	geriatr	geriatr	PROPN
fnp-3050	952	3	psychiatry	psychiatry	NOUN
fnp-3050	952	4	neurol	neurol	PROPN
fnp-3050	952	5	20:29	20:29	NUM
fnp-3050	952	6	-	-	SYM
fnp-3050	952	7	33	33	NUM
fnp-3050	952	8	213	213	NUM
fnp-3050	952	9	.	.	PUNCT
fnp-3050	952	10	scheff	scheff	PROPN
fnp-3050	952	11	sw	sw	PROPN
fnp-3050	952	12	,	,	PUNCT
fnp-3050	952	13	neltner	neltner	PROPN
fnp-3050	952	14	jh	jh	PROPN
fnp-3050	952	15	,	,	PUNCT
fnp-3050	952	16	nelson	nelson	PROPN
fnp-3050	952	17	pt	pt	PROPN
fnp-3050	952	18	(	(	PUNCT
fnp-3050	952	19	2014	2014	NUM
fnp-3050	952	20	)	)	PUNCT
fnp-3050	952	21	is	be	AUX
fnp-3050	952	22	synaptic	synaptic	ADJ
fnp-3050	952	23	loss	loss	NOUN
fnp-3050	952	24	a	a	DET
fnp-3050	952	25	unique	unique	ADJ
fnp-3050	952	26	hallmark	hallmark	NOUN
fnp-3050	952	27	of	of	ADP
fnp-3050	952	28	alzheimer	alzheimer	PROPN
fnp-3050	952	29	's	's	PART
fnp-3050	952	30	disease	disease	NOUN
fnp-3050	952	31	?	?	PUNCT
fnp-3050	953	1	biochem	biochem	PROPN
fnp-3050	953	2	pharmacol	pharmacol	PROPN
fnp-3050	953	3	88:517	88:517	PROPN
fnp-3050	953	4	-	-	PUNCT
fnp-3050	953	5	528	528	NUM
fnp-3050	953	6	214	214	NUM
fnp-3050	953	7	.	.	PUNCT
fnp-3050	954	1	yin	yin	PROPN
fnp-3050	954	2	z	z	PROPN
fnp-3050	954	3	,	,	PUNCT
fnp-3050	954	4	raj	raj	PROPN
fnp-3050	954	5	d	d	PROPN
fnp-3050	954	6	,	,	PUNCT
fnp-3050	954	7	saiepour	saiepour	PROPN
fnp-3050	954	8	n	n	CCONJ
fnp-3050	954	9	,	,	PUNCT
fnp-3050	954	10	van	van	PROPN
fnp-3050	954	11	dam	dam	PROPN
fnp-3050	954	12	d	d	PROPN
fnp-3050	954	13	,	,	PUNCT
fnp-3050	954	14	brouwer	brouwer	PROPN
fnp-3050	954	15	n	n	CCONJ
fnp-3050	954	16	,	,	PUNCT
fnp-3050	954	17	holtman	holtman	PROPN
fnp-3050	954	18	ir	ir	PROPN
fnp-3050	954	19	,	,	PUNCT
fnp-3050	954	20	eggen	eggen	NOUN
fnp-3050	954	21	bjl	bjl	NOUN
fnp-3050	954	22	,	,	PUNCT
fnp-3050	954	23	möller	möller	PROPN
fnp-3050	954	24	t	t	PROPN
fnp-3050	954	25	,	,	PUNCT
fnp-3050	954	26	tamm	tamm	PROPN
fnp-3050	954	27	ja	ja	PROPN
fnp-3050	954	28	,	,	PUNCT
fnp-3050	954	29	abdourahman	abdourahman	NOUN
fnp-3050	954	30	a	a	PRON
fnp-3050	954	31	,	,	PUNCT
fnp-3050	954	32	hol	hol	NOUN
fnp-3050	954	33	em	em	PRON
fnp-3050	954	34	,	,	PUNCT
fnp-3050	954	35	kamphuis	kamphuis	PROPN
fnp-3050	954	36	w	w	PROPN
fnp-3050	954	37	,	,	PUNCT
fnp-3050	954	38	bayer	bayer	PROPN
fnp-3050	954	39	ta	ta	PROPN
fnp-3050	954	40	,	,	PUNCT
fnp-3050	954	41	de	de	X
fnp-3050	954	42	deyn	deyn	NOUN
fnp-3050	954	43	pp	pp	ADV
fnp-3050	954	44	,	,	PUNCT
fnp-3050	954	45	boddeke	boddeke	PROPN
fnp-3050	954	46	e	e	X
fnp-3050	954	47	(	(	PUNCT
fnp-3050	954	48	2017	2017	NUM
fnp-3050	954	49	)	)	PUNCT
fnp-3050	954	50	immune	immune	ADJ
fnp-3050	954	51	hyperreactivity	hyperreactivity	NOUN
fnp-3050	954	52	of	of	ADP
fnp-3050	954	53	abeta	abeta	NOUN
fnp-3050	954	54	plaque	plaque	NOUN
fnp-3050	954	55	-	-	PUNCT
fnp-3050	954	56	associated	associate	VERB
fnp-3050	954	57	microglia	microglia	NOUN
fnp-3050	954	58	in	in	ADP
fnp-3050	954	59	alzheimer	alzheimer	PROPN
fnp-3050	954	60	's	's	PART
fnp-3050	954	61	disease	disease	NOUN
fnp-3050	954	62	.	.	PUNCT
fnp-3050	955	1	neurobiol	neurobiol	PROPN
fnp-3050	955	2	aging	age	VERB
fnp-3050	955	3	55:115	55:115	NUM
fnp-3050	955	4	-	-	SYM
fnp-3050	955	5	122	122	NUM
fnp-3050	955	6	215	215	NUM
fnp-3050	955	7	.	.	PUNCT
fnp-3050	956	1	zotova	zotova	PROPN
fnp-3050	956	2	e	e	X
fnp-3050	956	3	,	,	PUNCT
fnp-3050	956	4	bharambe	bharambe	ADP
fnp-3050	956	5	v	v	NOUN
fnp-3050	956	6	,	,	PUNCT
fnp-3050	956	7	cheaveau	cheaveau	NOUN
fnp-3050	956	8	m	m	PROPN
fnp-3050	956	9	,	,	PUNCT
fnp-3050	956	10	morgan	morgan	PROPN
fnp-3050	956	11	w	w	PROPN
fnp-3050	956	12	,	,	PUNCT
fnp-3050	956	13	holmes	holmes	PROPN
fnp-3050	956	14	c	c	PROPN
fnp-3050	956	15	,	,	PUNCT
fnp-3050	956	16	harris	harris	PROPN
fnp-3050	956	17	s	s	PROPN
fnp-3050	956	18	,	,	PUNCT
fnp-3050	956	19	neal	neal	PROPN
fnp-3050	956	20	jw	jw	PROPN
fnp-3050	956	21	,	,	PUNCT
fnp-3050	956	22	love	love	NOUN
fnp-3050	956	23	s	s	PROPN
fnp-3050	956	24	,	,	PUNCT
fnp-3050	956	25	nicoll	nicoll	PROPN
fnp-3050	956	26	ja	ja	PROPN
fnp-3050	956	27	,	,	PUNCT
fnp-3050	956	28	boche	boche	PROPN
fnp-3050	956	29	d	d	X
fnp-3050	956	30	(	(	PUNCT
fnp-3050	956	31	2013	2013	NUM
fnp-3050	956	32	)	)	PUNCT
fnp-3050	956	33	inflammatory	inflammatory	ADJ
fnp-3050	956	34	components	component	NOUN
fnp-3050	956	35	in	in	ADP
fnp-3050	956	36	human	human	PROPN
fnp-3050	956	37	alzheimer	alzheimer	PROPN
fnp-3050	956	38	's	's	PART
fnp-3050	956	39	disease	disease	NOUN
fnp-3050	956	40	and	and	CCONJ
fnp-3050	956	41	after	after	ADP
fnp-3050	956	42	active	active	ADJ
fnp-3050	956	43	amyloid	amyloid	NOUN
fnp-3050	956	44	-	-	PUNCT
fnp-3050	956	45	beta42	beta42	NOUN
fnp-3050	956	46	immunization	immunization	NOUN
fnp-3050	956	47	.	.	PUNCT
fnp-3050	957	1	brain	brain	NOUN
fnp-3050	957	2	136:2677	136:2677	NUM
fnp-3050	957	3	-	-	SYM
fnp-3050	957	4	2696	2696	NUM
fnp-3050	957	5	216	216	NUM
fnp-3050	957	6	.	.	PUNCT
fnp-3050	958	1	britschgi	britschgi	PROPN
fnp-3050	958	2	m	m	PROPN
fnp-3050	958	3	,	,	PUNCT
fnp-3050	958	4	takeda	takeda	PROPN
fnp-3050	958	5	-	-	PUNCT
fnp-3050	958	6	uchimura	uchimura	PROPN
fnp-3050	958	7	y	y	PROPN
fnp-3050	958	8	,	,	PUNCT
fnp-3050	958	9	rockenstein	rockenstein	PROPN
fnp-3050	958	10	e	e	PROPN
fnp-3050	958	11	,	,	PUNCT
fnp-3050	958	12	johns	johns	PROPN
fnp-3050	958	13	h	h	PROPN
fnp-3050	958	14	,	,	PUNCT
fnp-3050	958	15	masliah	masliah	PROPN
fnp-3050	958	16	e	e	NOUN
fnp-3050	958	17	,	,	PUNCT
fnp-3050	958	18	wyss	wyss	NOUN
fnp-3050	958	19	-	-	PUNCT
fnp-3050	958	20	coray	coray	NOUN
fnp-3050	958	21	t	t	NOUN
fnp-3050	958	22	(	(	PUNCT
fnp-3050	958	23	2012	2012	NUM
fnp-3050	958	24	)	)	PUNCT
fnp-3050	958	25	deficiency	deficiency	NOUN
fnp-3050	958	26	of	of	ADP
fnp-3050	958	27	terminal	terminal	ADJ
fnp-3050	958	28	complement	complement	NOUN
fnp-3050	958	29	pathway	pathway	NOUN
fnp-3050	958	30	inhibitor	inhibitor	NOUN
fnp-3050	958	31	promotes	promote	VERB
fnp-3050	958	32	neuronal	neuronal	ADJ
fnp-3050	958	33	tau	tau	PROPN
fnp-3050	958	34	pathology	pathology	NOUN
fnp-3050	958	35	and	and	CCONJ
fnp-3050	958	36	degeneration	degeneration	NOUN
fnp-3050	958	37	in	in	ADP
fnp-3050	958	38	mice	mouse	NOUN
fnp-3050	958	39	.	.	PUNCT
fnp-3050	959	1	j	j	PROPN
fnp-3050	959	2	neuroinflammation	neuroinflammation	NOUN
fnp-3050	959	3	9:220	9:220	NUM
fnp-3050	959	4	217	217	NUM
fnp-3050	959	5	.	.	PUNCT
fnp-3050	960	1	bolós	bolós	NOUN
fnp-3050	960	2	m	m	PROPN
fnp-3050	960	3	,	,	PUNCT
fnp-3050	960	4	llorens	llorens	PROPN
fnp-3050	960	5	-	-	PUNCT
fnp-3050	960	6	martín	martín	NOUN
fnp-3050	960	7	m	m	PROPN
fnp-3050	960	8	,	,	PUNCT
fnp-3050	960	9	jurado	jurado	PROPN
fnp-3050	960	10	-	-	PUNCT
fnp-3050	960	11	arjona	arjona	PROPN
fnp-3050	960	12	j	j	PROPN
fnp-3050	960	13	,	,	PUNCT
fnp-3050	960	14	hernández	hernández	PROPN
fnp-3050	960	15	f	f	PROPN
fnp-3050	960	16	,	,	PUNCT
fnp-3050	960	17	rábano	rábano	PROPN
fnp-3050	960	18	a	a	PRON
fnp-3050	960	19	,	,	PUNCT
fnp-3050	960	20	avila	avila	PROPN
fnp-3050	960	21	j	j	PROPN
fnp-3050	960	22	(	(	PUNCT
fnp-3050	960	23	2016	2016	NUM
fnp-3050	960	24	)	)	PUNCT
fnp-3050	960	25	direct	direct	ADJ
fnp-3050	960	26	evidence	evidence	NOUN
fnp-3050	960	27	of	of	ADP
fnp-3050	960	28	internalization	internalization	NOUN
fnp-3050	960	29	of	of	ADP
fnp-3050	960	30	tau	tau	PROPN
fnp-3050	960	31	by	by	ADP
fnp-3050	960	32	microglia	microglia	NOUN
fnp-3050	960	33	in	in	ADP
fnp-3050	960	34	vitro	vitro	X
fnp-3050	960	35	and	and	CCONJ
fnp-3050	960	36	in	in	ADP
fnp-3050	960	37	vivo	vivo	NOUN
fnp-3050	960	38	.	.	PUNCT
fnp-3050	961	1	j	j	PROPN
fnp-3050	961	2	alzheimers	alzheimers	PROPN
fnp-3050	961	3	dis	dis	PROPN
fnp-3050	961	4	50:77	50:77	NUM
fnp-3050	961	5	-	-	SYM
fnp-3050	961	6	87	87	NUM
fnp-3050	961	7	218	218	NUM
fnp-3050	961	8	.	.	PUNCT
fnp-3050	962	1	luo	luo	PROPN
fnp-3050	962	2	w	w	PROPN
fnp-3050	962	3	,	,	PUNCT
fnp-3050	962	4	liu	liu	PROPN
fnp-3050	962	5	w	w	PROPN
fnp-3050	962	6	,	,	PUNCT
fnp-3050	962	7	hu	hu	PROPN
fnp-3050	962	8	x	x	PROPN
fnp-3050	962	9	,	,	PUNCT
fnp-3050	962	10	hanna	hanna	PROPN
fnp-3050	962	11	m	m	PROPN
fnp-3050	962	12	,	,	PUNCT
fnp-3050	962	13	caravaca	caravaca	PROPN
fnp-3050	962	14	a	a	X
fnp-3050	962	15	,	,	PUNCT
fnp-3050	962	16	paul	paul	PROPN
fnp-3050	962	17	sm	sm	PROPN
fnp-3050	962	18	(	(	PUNCT
fnp-3050	962	19	2015	2015	NUM
fnp-3050	962	20	)	)	PUNCT
fnp-3050	962	21	microglial	microglial	ADJ
fnp-3050	962	22	internalization	internalization	NOUN
fnp-3050	962	23	and	and	CCONJ
fnp-3050	962	24	degradation	degradation	NOUN
fnp-3050	962	25	of	of	ADP
fnp-3050	962	26	pathological	pathological	ADJ
fnp-3050	962	27	tau	tau	PROPN
fnp-3050	962	28	is	be	AUX
fnp-3050	962	29	enhanced	enhance	VERB
fnp-3050	962	30	by	by	ADP
fnp-3050	962	31	an	an	DET
fnp-3050	962	32	anti	anti	ADJ
fnp-3050	962	33	-	-	ADJ
fnp-3050	962	34	tau	tau	ADJ
fnp-3050	962	35	monoclonal	monoclonal	NOUN
fnp-3050	962	36	antibody	antibody	NOUN
fnp-3050	962	37	.	.	PUNCT
fnp-3050	963	1	sci	sci	PROPN
fnp-3050	963	2	rep	rep	PROPN
fnp-3050	963	3	5:11161	5:11161	PROPN
fnp-3050	963	4	219	219	NUM
fnp-3050	963	5	.	.	PUNCT
fnp-3050	964	1	van	van	PROPN
fnp-3050	964	2	olst	olst	PROPN
fnp-3050	964	3	l	l	PROPN
fnp-3050	964	4	,	,	PUNCT
fnp-3050	964	5	verhaege	verhaege	PROPN
fnp-3050	964	6	d	d	NOUN
fnp-3050	964	7	,	,	PUNCT
fnp-3050	964	8	franssen	franssen	PROPN
fnp-3050	964	9	m	m	PROPN
fnp-3050	964	10	,	,	PUNCT
fnp-3050	964	11	kamermans	kamerman	VERB
fnp-3050	964	12	a	a	DET
fnp-3050	964	13	,	,	PUNCT
fnp-3050	964	14	roucourt	roucourt	NOUN
fnp-3050	964	15	b	b	PROPN
fnp-3050	964	16	,	,	PUNCT
fnp-3050	964	17	carmans	carmans	PROPN
fnp-3050	964	18	s	s	PART
fnp-3050	964	19	,	,	PUNCT
fnp-3050	964	20	ytebrouck	ytebrouck	VERB
fnp-3050	964	21	e	e	NOUN
fnp-3050	964	22	,	,	PUNCT
fnp-3050	964	23	van	van	PROPN
fnp-3050	964	24	der	der	PROPN
fnp-3050	964	25	pol	pol	PROPN
fnp-3050	964	26	sma	sma	PROPN
fnp-3050	964	27	,	,	PUNCT
fnp-3050	964	28	wever	wever	PROPN
fnp-3050	964	29	d	d	PROPN
fnp-3050	964	30	,	,	PUNCT
fnp-3050	964	31	popovic	popovic	PROPN
fnp-3050	964	32	m	m	PROPN
fnp-3050	964	33	,	,	PUNCT
fnp-3050	964	34	vandenbroucke	vandenbroucke	NOUN
fnp-3050	964	35	re	re	PROPN
fnp-3050	964	36	,	,	PUNCT
fnp-3050	964	37	sobrino	sobrino	PROPN
fnp-3050	964	38	t	t	PROPN
fnp-3050	964	39	,	,	PUNCT
fnp-3050	964	40	schouten	schouten	PROPN
fnp-3050	964	41	m	m	PROPN
fnp-3050	964	42	,	,	PUNCT
fnp-3050	964	43	de	de	PROPN
fnp-3050	964	44	vries	vries	PROPN
fnp-3050	964	45	he	he	PRON
fnp-3050	964	46	(	(	PUNCT
fnp-3050	964	47	2020	2020	NUM
fnp-3050	964	48	)	)	PUNCT
fnp-3050	964	49	microglial	microglial	ADJ
fnp-3050	964	50	activation	activation	NOUN
fnp-3050	964	51	arises	arise	VERB
fnp-3050	964	52	after	after	ADP
fnp-3050	964	53	aggregation	aggregation	NOUN
fnp-3050	964	54	of	of	ADP
fnp-3050	964	55	phosphorylated	phosphorylate	VERB
fnp-3050	964	56	-	-	PUNCT
fnp-3050	964	57	tau	tau	NOUN
fnp-3050	964	58	in	in	ADP
fnp-3050	964	59	a	a	DET
fnp-3050	964	60	neuron	neuron	NOUN
fnp-3050	964	61	-	-	PUNCT
fnp-3050	964	62	specific	specific	ADJ
fnp-3050	964	63	p301s	p301s	PROPN
fnp-3050	964	64	tauopathy	tauopathy	ADJ
fnp-3050	964	65	mouse	mouse	NOUN
fnp-3050	964	66	model	model	NOUN
fnp-3050	964	67	.	.	PUNCT
fnp-3050	965	1	neurobiol	neurobiol	VERB
fnp-3050	965	2	aging	age	VERB
fnp-3050	965	3	89:89	89:89	NUM
fnp-3050	965	4	-	-	SYM
fnp-3050	965	5	98	98	NUM
fnp-3050	965	6	220	220	NUM
fnp-3050	965	7	.	.	PUNCT
fnp-3050	966	1	zhu	zhu	PROPN
fnp-3050	966	2	k	k	PROPN
fnp-3050	966	3	,	,	PUNCT
fnp-3050	966	4	pieber	pieber	PROPN
fnp-3050	966	5	m	m	PROPN
fnp-3050	966	6	,	,	PUNCT
fnp-3050	966	7	han	han	PROPN
fnp-3050	966	8	j	j	PROPN
fnp-3050	966	9	,	,	PUNCT
fnp-3050	966	10	blomgren	blomgren	PROPN
fnp-3050	966	11	k	k	PROPN
fnp-3050	966	12	,	,	PUNCT
fnp-3050	966	13	zhang	zhang	PROPN
fnp-3050	966	14	xm	xm	PROPN
fnp-3050	966	15	,	,	PUNCT
fnp-3050	966	16	harris	harris	PROPN
fnp-3050	966	17	ra	ra	PROPN
fnp-3050	966	18	,	,	PUNCT
fnp-3050	966	19	lund	lund	PROPN
fnp-3050	966	20	h	h	PROPN
fnp-3050	966	21	(	(	PUNCT
fnp-3050	966	22	2020	2020	NUM
fnp-3050	966	23	)	)	PUNCT
fnp-3050	966	24	absence	absence	NOUN
fnp-3050	966	25	of	of	ADP
fnp-3050	966	26	microglia	microglia	NOUN
fnp-3050	966	27	or	or	CCONJ
fnp-3050	966	28	presence	presence	NOUN
fnp-3050	966	29	of	of	ADP
fnp-3050	966	30	peripherally	peripherally	ADV
fnp-3050	966	31	-	-	PUNCT
fnp-3050	966	32	derived	derive	VERB
fnp-3050	966	33	macrophages	macrophage	NOUN
fnp-3050	966	34	does	do	AUX
fnp-3050	966	35	not	not	PART
fnp-3050	966	36	affect	affect	VERB
fnp-3050	966	37	tau	tau	PROPN
fnp-3050	966	38	pathology	pathology	NOUN
fnp-3050	966	39	in	in	ADP
fnp-3050	966	40	young	young	ADJ
fnp-3050	966	41	or	or	CCONJ
fnp-3050	966	42	old	old	ADJ
fnp-3050	966	43	htau	htau	ADJ
fnp-3050	966	44	mice	mouse	NOUN
fnp-3050	966	45	.	.	PUNCT
fnp-3050	967	1	glia	glia	NOUN
fnp-3050	967	2	68:1466	68:1466	NUM
fnp-3050	967	3	-	-	SYM
fnp-3050	967	4	1478	1478	NUM
fnp-3050	967	5	221	221	NUM
fnp-3050	967	6	.	.	PUNCT
fnp-3050	968	1	walker	walker	PROPN
fnp-3050	968	2	dg	dg	PROPN
fnp-3050	968	3	(	(	PUNCT
fnp-3050	968	4	2020	2020	NUM
fnp-3050	968	5	)	)	PUNCT
fnp-3050	968	6	defining	define	VERB
fnp-3050	968	7	activation	activation	NOUN
fnp-3050	968	8	states	state	NOUN
fnp-3050	968	9	of	of	ADP
fnp-3050	968	10	microglia	microglia	NOUN
fnp-3050	968	11	in	in	ADP
fnp-3050	968	12	human	human	ADJ
fnp-3050	968	13	brain	brain	NOUN
fnp-3050	968	14	tissue	tissue	NOUN
fnp-3050	968	15	:	:	PUNCT
fnp-3050	968	16	an	an	DET
fnp-3050	968	17	unresolved	unresolved	ADJ
fnp-3050	968	18	issue	issue	NOUN
fnp-3050	968	19	for	for	ADP
fnp-3050	968	20	alzheimer	alzheimer	PROPN
fnp-3050	968	21	’s	’s	PART
fnp-3050	968	22	disease	disease	NOUN
fnp-3050	968	23	.	.	PUNCT
fnp-3050	969	1	neuroimmunol	neuroimmunol	NOUN
fnp-3050	969	2	neuroinflammation	neuroinflammation	NOUN
fnp-3050	969	3	7:194	7:194	NOUN
fnp-3050	969	4	-	-	SYM
fnp-3050	969	5	214	214	NUM
fnp-3050	969	6	;	;	PUNCT
fnp-3050	969	7	doi	doi	NOUN
fnp-3050	969	8	:	:	PUNCT
fnp-3050	969	9	110.20517/22347	110.20517/22347	NUM
fnp-3050	969	10	-	-	SYM
fnp-3050	969	11	28659.22020.20509	28659.22020.20509	NUM
fnp-3050	969	12	222	222	NUM
fnp-3050	969	13	.	.	PUNCT
fnp-3050	970	1	paasila	paasila	PROPN
fnp-3050	970	2	pj	pj	PROPN
fnp-3050	970	3	,	,	PUNCT
fnp-3050	970	4	davies	davy	NOUN
fnp-3050	970	5	ds	ds	PROPN
fnp-3050	970	6	,	,	PUNCT
fnp-3050	970	7	kril	kril	PROPN
fnp-3050	970	8	jj	jj	PROPN
fnp-3050	970	9	,	,	PUNCT
fnp-3050	970	10	goldsbury	goldsbury	NOUN
fnp-3050	970	11	c	c	PROPN
fnp-3050	970	12	,	,	PUNCT
fnp-3050	970	13	sutherland	sutherland	PROPN
fnp-3050	970	14	gt	gt	PROPN
fnp-3050	970	15	(	(	PUNCT
fnp-3050	970	16	2019	2019	NUM
fnp-3050	970	17	)	)	PUNCT
fnp-3050	970	18	the	the	DET
fnp-3050	970	19	relationship	relationship	NOUN
fnp-3050	970	20	between	between	ADP
fnp-3050	970	21	the	the	DET
fnp-3050	970	22	morphological	morphological	ADJ
fnp-3050	970	23	subtypes	subtype	NOUN
fnp-3050	970	24	of	of	ADP
fnp-3050	970	25	microglia	microglia	NOUN
fnp-3050	970	26	and	and	CCONJ
fnp-3050	970	27	alzheimer	alzheimer	PROPN
fnp-3050	970	28	's	's	PART
fnp-3050	970	29	disease	disease	NOUN
fnp-3050	970	30	neuropathology	neuropathology	NOUN
fnp-3050	970	31	.	.	PUNCT
fnp-3050	971	1	brain	brain	NOUN
fnp-3050	971	2	pathol	pathol	NOUN
fnp-3050	971	3	29:726	29:726	NUM
fnp-3050	971	4	-	-	SYM
fnp-3050	971	5	740	740	NUM
fnp-3050	971	6	223	223	NUM
fnp-3050	971	7	.	.	PUNCT
fnp-3050	972	1	baulch	baulch	PROPN
fnp-3050	972	2	je	je	PROPN
fnp-3050	972	3	,	,	PUNCT
fnp-3050	972	4	acharya	acharya	PROPN
fnp-3050	972	5	mm	mm	PROPN
fnp-3050	972	6	,	,	PUNCT
fnp-3050	972	7	agrawal	agrawal	PROPN
fnp-3050	972	8	s	s	PROPN
fnp-3050	972	9	,	,	PUNCT
fnp-3050	972	10	apodaca	apodaca	PROPN
fnp-3050	972	11	la	la	PROPN
fnp-3050	972	12	,	,	PUNCT
fnp-3050	972	13	monteiro	monteiro	PROPN
fnp-3050	972	14	c	c	PROPN
fnp-3050	972	15	,	,	PUNCT
fnp-3050	972	16	agrawal	agrawal	VERB
fnp-3050	972	17	a	a	DET
fnp-3050	972	18	(	(	PUNCT
fnp-3050	972	19	2020	2020	NUM
fnp-3050	972	20	)	)	PUNCT
fnp-3050	972	21	immune	immune	ADJ
fnp-3050	972	22	and	and	CCONJ
fnp-3050	972	23	inflammatory	inflammatory	ADJ
fnp-3050	972	24	determinants	determinant	NOUN
fnp-3050	972	25	underlying	underlie	VERB
fnp-3050	972	26	alzheimer	alzheimer	NOUN
fnp-3050	972	27	's	's	PART
fnp-3050	972	28	disease	disease	NOUN
fnp-3050	972	29	pathology	pathology	NOUN
fnp-3050	972	30	.	.	PUNCT
fnp-3050	973	1	j	j	PROPN
fnp-3050	973	2	neuroimmune	neuroimmune	PROPN
fnp-3050	973	3	pharmacol	pharmacol	PROPN
fnp-3050	973	4	feb	feb	PROPN
fnp-3050	973	5	22	22	NUM
fnp-3050	973	6	:	:	PUNCT
fnp-3050	973	7	doi	doi	NOUN
fnp-3050	973	8	:	:	PUNCT
fnp-3050	973	9	10.1007	10.1007	NUM
fnp-3050	973	10	/	/	SYM
fnp-3050	973	11	s11481	s11481	NOUN
fnp-3050	973	12	-	-	PUNCT
fnp-3050	973	13	11020	11020	NUM
fnp-3050	973	14	-	-	PUNCT
fnp-3050	973	15	09908	09908	NUM
fnp-3050	973	16	-	-	PUNCT
fnp-3050	973	17	11489	11489	NUM
fnp-3050	973	18	224	224	NUM
fnp-3050	973	19	.	.	PUNCT
fnp-3050	974	1	jicha	jicha	PROPN
fnp-3050	974	2	ga	ga	PROPN
fnp-3050	974	3	,	,	PUNCT
fnp-3050	974	4	parisi	parisi	PROPN
fnp-3050	974	5	je	je	PROPN
fnp-3050	974	6	,	,	PUNCT
fnp-3050	974	7	dickson	dickson	PROPN
fnp-3050	974	8	dw	dw	PROPN
fnp-3050	974	9	,	,	PUNCT
fnp-3050	974	10	johnson	johnson	PROPN
fnp-3050	974	11	k	k	PROPN
fnp-3050	974	12	,	,	PUNCT
fnp-3050	974	13	cha	cha	PROPN
fnp-3050	974	14	r	r	NOUN
fnp-3050	974	15	,	,	PUNCT
fnp-3050	974	16	ivnik	ivnik	X
fnp-3050	974	17	rj	rj	PROPN
fnp-3050	974	18	,	,	PUNCT
fnp-3050	974	19	tangalos	tangalos	PROPN
fnp-3050	974	20	eg	eg	PROPN
fnp-3050	974	21	,	,	PUNCT
fnp-3050	974	22	boeve	boeve	NOUN
fnp-3050	974	23	bf	bf	NOUN
fnp-3050	974	24	,	,	PUNCT
fnp-3050	974	25	knopman	knopman	NOUN
fnp-3050	974	26	ds	ds	PROPN
fnp-3050	974	27	,	,	PUNCT
fnp-3050	974	28	braak	braak	NOUN
fnp-3050	974	29	h	h	NOUN
fnp-3050	974	30	,	,	PUNCT
fnp-3050	974	31	petersen	petersen	PROPN
fnp-3050	974	32	rc	rc	PROPN
fnp-3050	974	33	(	(	PUNCT
fnp-3050	974	34	2006	2006	NUM
fnp-3050	974	35	)	)	PUNCT
fnp-3050	974	36	neuropathologic	neuropathologic	ADJ
fnp-3050	974	37	outcome	outcome	NOUN
fnp-3050	974	38	of	of	ADP
fnp-3050	974	39	mild	mild	ADJ
fnp-3050	974	40	cognitive	cognitive	ADJ
fnp-3050	974	41	impairment	impairment	NOUN
fnp-3050	974	42	following	follow	VERB
fnp-3050	974	43	progression	progression	NOUN
fnp-3050	974	44	to	to	ADP
fnp-3050	974	45	clinical	clinical	ADJ
fnp-3050	974	46	dementia	dementia	NOUN
fnp-3050	974	47	.	.	PUNCT
fnp-3050	975	1	arch	arch	ADJ
fnp-3050	975	2	neurol	neurol	PROPN
fnp-3050	975	3	63:674	63:674	PROPN
fnp-3050	975	4	-	-	SYM
fnp-3050	975	5	681	681	NUM
fnp-3050	975	6	225	225	NUM
fnp-3050	975	7	.	.	PUNCT
fnp-3050	976	1	sperling	sperling	PROPN
fnp-3050	976	2	ra	ra	PROPN
fnp-3050	976	3	,	,	PUNCT
fnp-3050	976	4	aisen	aisen	PROPN
fnp-3050	976	5	ps	ps	PROPN
fnp-3050	976	6	,	,	PUNCT
fnp-3050	976	7	beckett	beckett	PROPN
fnp-3050	976	8	la	la	PROPN
fnp-3050	976	9	,	,	PUNCT
fnp-3050	976	10	bennett	bennett	PROPN
fnp-3050	976	11	da	da	PROPN
fnp-3050	976	12	,	,	PUNCT
fnp-3050	976	13	craft	craft	NOUN
fnp-3050	976	14	s	s	PART
fnp-3050	976	15	,	,	PUNCT
fnp-3050	976	16	fagan	fagan	PROPN
fnp-3050	976	17	am	be	AUX
fnp-3050	976	18	,	,	PUNCT
fnp-3050	976	19	iwatsubo	iwatsubo	PROPN
fnp-3050	976	20	t	t	PROPN
fnp-3050	976	21	,	,	PUNCT
fnp-3050	976	22	jack	jack	PROPN
fnp-3050	976	23	cr	cr	PROPN
fnp-3050	976	24	,	,	PUNCT
fnp-3050	976	25	jr	jr	PROPN
fnp-3050	976	26	.	.	PROPN
fnp-3050	976	27	,	,	PUNCT
fnp-3050	976	28	kaye	kaye	PROPN
fnp-3050	976	29	j	j	PROPN
fnp-3050	976	30	,	,	PUNCT
fnp-3050	976	31	montine	montine	PROPN
fnp-3050	976	32	tj	tj	PROPN
fnp-3050	976	33	,	,	PUNCT
fnp-3050	976	34	park	park	PROPN
fnp-3050	976	35	dc	dc	PROPN
fnp-3050	976	36	,	,	PUNCT
fnp-3050	976	37	reiman	reiman	VERB
fnp-3050	976	38	em	em	PRON
fnp-3050	976	39	,	,	PUNCT
fnp-3050	976	40	rowe	rowe	PROPN
fnp-3050	976	41	cc	cc	PROPN
fnp-3050	976	42	,	,	PUNCT
fnp-3050	976	43	siemers	siemer	NOUN
fnp-3050	976	44	e	e	NOUN
fnp-3050	976	45	,	,	PUNCT
fnp-3050	976	46	stern	stern	PROPN
fnp-3050	976	47	y	y	PROPN
fnp-3050	976	48	,	,	PUNCT
fnp-3050	976	49	yaffe	yaffe	PROPN
fnp-3050	976	50	k	k	PROPN
fnp-3050	976	51	,	,	PUNCT
fnp-3050	976	52	carrillo	carrillo	PROPN
fnp-3050	976	53	mc	mc	PROPN
fnp-3050	976	54	,	,	PUNCT
fnp-3050	976	55	thies	thies	PROPN
fnp-3050	976	56	b	b	NUM
fnp-3050	976	57	,	,	PUNCT
fnp-3050	976	58	morrison	morrison	PROPN
fnp-3050	976	59	-	-	PUNCT
fnp-3050	976	60	bogorad	bogorad	PROPN
fnp-3050	976	61	m	m	PROPN
fnp-3050	976	62	,	,	PUNCT
fnp-3050	976	63	wagster	wagster	ADJ
fnp-3050	976	64	mv	mv	PROPN
fnp-3050	976	65	,	,	PUNCT
fnp-3050	976	66	phelps	phelps	PROPN
fnp-3050	976	67	ch	ch	PROPN
fnp-3050	976	68	(	(	PUNCT
fnp-3050	976	69	2011	2011	NUM
fnp-3050	976	70	)	)	PUNCT
fnp-3050	976	71	toward	toward	ADP
fnp-3050	976	72	defining	define	VERB
fnp-3050	976	73	the	the	DET
fnp-3050	976	74	preclinical	preclinical	ADJ
fnp-3050	976	75	stages	stage	NOUN
fnp-3050	976	76	of	of	ADP
fnp-3050	976	77	alzheimer	alzheimer	PROPN
fnp-3050	976	78	's	's	PART
fnp-3050	976	79	disease	disease	NOUN
fnp-3050	976	80	:	:	PUNCT
fnp-3050	976	81	recommendations	recommendation	NOUN
fnp-3050	976	82	from	from	ADP
fnp-3050	976	83	the	the	DET
fnp-3050	976	84	national	national	PROPN
fnp-3050	976	85	institute	institute	PROPN
fnp-3050	976	86	on	on	ADP
fnp-3050	976	87	aging	age	VERB
fnp-3050	976	88	-	-	PUNCT
fnp-3050	976	89	alzheimer	alzheimer	NOUN
fnp-3050	976	90	's	's	PART
fnp-3050	976	91	association	association	NOUN
fnp-3050	976	92	workgroups	workgroup	NOUN
fnp-3050	976	93	on	on	ADP
fnp-3050	976	94	diagnostic	diagnostic	ADJ
fnp-3050	976	95	guidelines	guideline	NOUN
fnp-3050	976	96	for	for	ADP
fnp-3050	976	97	alzheimer	alzheimer	PROPN
fnp-3050	976	98	's	's	PART
fnp-3050	976	99	disease	disease	NOUN
fnp-3050	976	100	.	.	PUNCT
fnp-3050	977	1	alzheimers	alzheimers	PROPN
fnp-3050	977	2	dement	dement	PROPN
fnp-3050	977	3	7:280	7:280	PROPN
fnp-3050	977	4	-	-	SYM
fnp-3050	977	5	292	292	NUM
fnp-3050	977	6	226	226	NUM
fnp-3050	977	7	.	.	PUNCT
fnp-3050	978	1	thal	thal	PROPN
fnp-3050	978	2	dr	dr	PROPN
fnp-3050	978	3	,	,	PUNCT
fnp-3050	978	4	von	von	PROPN
fnp-3050	978	5	arnim	arnim	PROPN
fnp-3050	978	6	c	c	PROPN
fnp-3050	978	7	,	,	PUNCT
fnp-3050	978	8	griffin	griffin	PROPN
fnp-3050	978	9	ws	ws	PROPN
fnp-3050	978	10	,	,	PUNCT
fnp-3050	978	11	yamaguchi	yamaguchi	PROPN
fnp-3050	978	12	h	h	PROPN
fnp-3050	978	13	,	,	PUNCT
fnp-3050	978	14	mrak	mrak	PROPN
fnp-3050	978	15	re	re	NOUN
fnp-3050	978	16	,	,	PUNCT
fnp-3050	978	17	attems	attem	VERB
fnp-3050	978	18	j	j	PROPN
fnp-3050	978	19	,	,	PUNCT
fnp-3050	978	20	upadhaya	upadhaya	PROPN
fnp-3050	978	21	ar	ar	PROPN
fnp-3050	978	22	(	(	PUNCT
fnp-3050	978	23	2013	2013	NUM
fnp-3050	978	24	)	)	PUNCT
fnp-3050	978	25	pathology	pathology	NOUN
fnp-3050	978	26	of	of	ADP
fnp-3050	978	27	clinical	clinical	ADJ
fnp-3050	978	28	and	and	CCONJ
fnp-3050	978	29	preclinical	preclinical	ADJ
fnp-3050	978	30	alzheimer	alzheimer	NOUN
fnp-3050	978	31	's	's	PART
fnp-3050	978	32	disease	disease	NOUN
fnp-3050	978	33	.	.	PUNCT
fnp-3050	979	1	eur	eur	PROPN
fnp-3050	979	2	arch	arch	PROPN
fnp-3050	979	3	psychiatry	psychiatry	PROPN
fnp-3050	979	4	clin	clin	PROPN
fnp-3050	979	5	neurosci	neurosci	PROPN
fnp-3050	979	6	263	263	NUM
fnp-3050	979	7	suppl	suppl	ADJ
fnp-3050	979	8	2	2	NUM
fnp-3050	979	9	:	:	PUNCT
fnp-3050	979	10	s137	s137	PROPN
fnp-3050	979	11	-	-	SYM
fnp-3050	979	12	145	145	NUM
fnp-3050	979	13	227	227	NUM
fnp-3050	979	14	.	.	PUNCT
fnp-3050	980	1	jack	jack	PROPN
fnp-3050	980	2	cr	cr	PROPN
fnp-3050	980	3	,	,	PUNCT
fnp-3050	980	4	wiste	wiste	PROPN
fnp-3050	980	5	hj	hj	PROPN
fnp-3050	980	6	,	,	PUNCT
fnp-3050	980	7	weigand	weigand	NOUN
fnp-3050	980	8	sd	sd	NOUN
fnp-3050	980	9	,	,	PUNCT
fnp-3050	980	10	therneau	therneau	PROPN
fnp-3050	980	11	tm	tm	PROPN
fnp-3050	980	12	,	,	PUNCT
fnp-3050	980	13	lowe	lowe	PROPN
fnp-3050	980	14	vj	vj	PROPN
fnp-3050	980	15	,	,	PUNCT
fnp-3050	980	16	knopman	knopman	NOUN
fnp-3050	980	17	ds	ds	PROPN
fnp-3050	980	18	,	,	PUNCT
fnp-3050	980	19	botha	botha	PROPN
fnp-3050	980	20	h	h	PROPN
fnp-3050	980	21	,	,	PUNCT
fnp-3050	980	22	graff	graff	PROPN
fnp-3050	980	23	-	-	PUNCT
fnp-3050	980	24	radford	radford	PROPN
fnp-3050	980	25	j	j	PROPN
fnp-3050	980	26	,	,	PUNCT
fnp-3050	980	27	jones	jones	PROPN
fnp-3050	980	28	dt	dt	PROPN
fnp-3050	980	29	,	,	PUNCT
fnp-3050	980	30	ferman	ferman	PROPN
fnp-3050	980	31	tj	tj	PROPN
fnp-3050	980	32	,	,	PUNCT
fnp-3050	980	33	boeve	boeve	NOUN
fnp-3050	980	34	bf	bf	NOUN
fnp-3050	980	35	,	,	PUNCT
fnp-3050	980	36	kantarci	kantarci	PROPN
fnp-3050	980	37	k	k	PROPN
fnp-3050	980	38	,	,	PUNCT
fnp-3050	980	39	vemuri	vemuri	X
fnp-3050	980	40	p	p	X
fnp-3050	980	41	,	,	PUNCT
fnp-3050	980	42	mielke	mielke	ADV
fnp-3050	980	43	mm	mm	PROPN
fnp-3050	980	44	,	,	PUNCT
fnp-3050	980	45	whitwell	whitwell	PROPN
fnp-3050	980	46	j	j	PROPN
fnp-3050	980	47	,	,	PUNCT
fnp-3050	980	48	josephs	josephs	PROPN
fnp-3050	980	49	k	k	PROPN
fnp-3050	980	50	,	,	PUNCT
fnp-3050	980	51	schwarz	schwarz	PROPN
fnp-3050	980	52	cg	cg	PROPN
fnp-3050	980	53	,	,	PUNCT
fnp-3050	980	54	senjem	senjem	NOUN
fnp-3050	980	55	ml	ml	PROPN
fnp-3050	980	56	,	,	PUNCT
fnp-3050	980	57	gunter	gunter	NOUN
fnp-3050	980	58	jl	jl	PROPN
fnp-3050	980	59	,	,	PUNCT
fnp-3050	980	60	petersen	petersen	PROPN
fnp-3050	980	61	rc	rc	PROPN
fnp-3050	980	62	(	(	PUNCT
fnp-3050	980	63	2020	2020	NUM
fnp-3050	980	64	)	)	PUNCT
fnp-3050	980	65	predicting	predict	VERB
fnp-3050	980	66	future	future	ADJ
fnp-3050	980	67	rates	rate	NOUN
fnp-3050	980	68	of	of	ADP
fnp-3050	980	69	tau	tau	PROPN
fnp-3050	980	70	accumulation	accumulation	NOUN
fnp-3050	980	71	on	on	ADP
fnp-3050	980	72	pet	pet	PROPN
fnp-3050	980	73	.	.	PUNCT
fnp-3050	981	1	brain	brain	PROPN
fnp-3050	981	2	143:3136	143:3136	PROPN
fnp-3050	981	3	-	-	SYM
fnp-3050	981	4	3150	3150	NUM
fnp-3050	981	5	228	228	NUM
fnp-3050	981	6	.	.	PUNCT
fnp-3050	982	1	alafuzoff	alafuzoff	PROPN
fnp-3050	983	1	i	i	PRON
fnp-3050	983	2	,	,	PUNCT
fnp-3050	983	3	arzberger	arzberger	PROPN
fnp-3050	983	4	t	t	PROPN
fnp-3050	983	5	,	,	PUNCT
fnp-3050	983	6	al	al	PROPN
fnp-3050	983	7	-	-	PUNCT
fnp-3050	983	8	sarraj	sarraj	VERB
fnp-3050	983	9	s	s	PROPN
fnp-3050	983	10	,	,	PUNCT
fnp-3050	983	11	bodi	bodi	PROPN
fnp-3050	983	12	i	i	PROPN
fnp-3050	983	13	,	,	PUNCT
fnp-3050	983	14	bogdanovic	bogdanovic	PROPN
fnp-3050	983	15	n	n	CCONJ
fnp-3050	983	16	,	,	PUNCT
fnp-3050	983	17	braak	braak	PROPN
fnp-3050	983	18	h	h	PROPN
fnp-3050	983	19	,	,	PUNCT
fnp-3050	983	20	bugiani	bugiani	PROPN
fnp-3050	983	21	o	o	PROPN
fnp-3050	983	22	,	,	PUNCT
fnp-3050	983	23	del	del	PROPN
fnp-3050	983	24	-	-	NOUN
fnp-3050	983	25	tredici	tredici	PROPN
fnp-3050	983	26	k	k	PROPN
fnp-3050	983	27	,	,	PUNCT
fnp-3050	983	28	ferrer	ferrer	PROPN
fnp-3050	983	29	i	i	PROPN
fnp-3050	983	30	,	,	PUNCT
fnp-3050	983	31	gelpi	gelpi	NOUN
fnp-3050	983	32	e	e	NOUN
fnp-3050	983	33	,	,	PUNCT
fnp-3050	983	34	giaccone	giaccone	PROPN
fnp-3050	983	35	g	g	PROPN
fnp-3050	983	36	,	,	PUNCT
fnp-3050	983	37	graeber	graeber	NOUN
fnp-3050	983	38	mb	mb	PROPN
fnp-3050	983	39	,	,	PUNCT
fnp-3050	983	40	ince	ince	NOUN
fnp-3050	983	41	p	p	PRON
fnp-3050	983	42	,	,	PUNCT
fnp-3050	983	43	kamphorst	kamphorst	ADJ
fnp-3050	983	44	w	w	PROPN
fnp-3050	983	45	,	,	PUNCT
fnp-3050	983	46	king	king	NOUN
fnp-3050	983	47	a	a	PRON
fnp-3050	983	48	,	,	PUNCT
fnp-3050	983	49	korkolopoulou	korkolopoulou	PROPN
fnp-3050	983	50	p	p	X
fnp-3050	983	51	,	,	PUNCT
fnp-3050	983	52	kovacs	kovacs	PROPN
fnp-3050	983	53	gg	gg	PROPN
fnp-3050	983	54	,	,	PUNCT
fnp-3050	983	55	larionov	larionov	PROPN
fnp-3050	983	56	s	s	PROPN
fnp-3050	983	57	,	,	PUNCT
fnp-3050	983	58	meyronet	meyronet	NOUN
fnp-3050	983	59	d	d	NOUN
fnp-3050	983	60	,	,	PUNCT
fnp-3050	983	61	monoranu	monoranu	PROPN
fnp-3050	983	62	c	c	NOUN
fnp-3050	983	63	,	,	PUNCT
fnp-3050	983	64	parchi	parchi	VERB
fnp-3050	983	65	p	p	NOUN
fnp-3050	983	66	,	,	PUNCT
fnp-3050	983	67	patsouris	patsouris	PROPN
fnp-3050	983	68	e	e	NOUN
fnp-3050	983	69	,	,	PUNCT
fnp-3050	983	70	roggendorf	roggendorf	PROPN
fnp-3050	983	71	w	w	PROPN
fnp-3050	983	72	,	,	PUNCT
fnp-3050	983	73	seilhean	seilhean	PROPN
fnp-3050	983	74	d	d	PROPN
fnp-3050	983	75	,	,	PUNCT
fnp-3050	983	76	tagliavini	tagliavini	PROPN
fnp-3050	983	77	f	f	NOUN
fnp-3050	983	78	,	,	PUNCT
fnp-3050	983	79	stadelmann	stadelmann	PROPN
fnp-3050	983	80	c	c	NOUN
fnp-3050	983	81	,	,	PUNCT
fnp-3050	983	82	streichenberger	streichenberg	ADJ
fnp-3050	983	83	n	n	NOUN
fnp-3050	983	84	,	,	PUNCT
fnp-3050	983	85	thal	thal	PROPN
fnp-3050	983	86	dr	dr	PROPN
fnp-3050	983	87	,	,	PUNCT
fnp-3050	983	88	wharton	wharton	PROPN
fnp-3050	983	89	sb	sb	PROPN
fnp-3050	983	90	,	,	PUNCT
fnp-3050	983	91	kretzschmar	kretzschmar	PROPN
fnp-3050	983	92	h	h	PROPN
fnp-3050	983	93	(	(	PUNCT
fnp-3050	983	94	2008	2008	NUM
fnp-3050	983	95	)	)	PUNCT
fnp-3050	983	96	staging	staging	NOUN
fnp-3050	983	97	of	of	ADP
fnp-3050	983	98	neurofibrillary	neurofibrillary	ADJ
fnp-3050	983	99	pathology	pathology	NOUN
fnp-3050	983	100	in	in	ADP
fnp-3050	983	101	alzheimer	alzheimer	PROPN
fnp-3050	983	102	's	's	PART
fnp-3050	983	103	disease	disease	NOUN
fnp-3050	983	104	:	:	PUNCT
fnp-3050	983	105	a	a	DET
fnp-3050	983	106	study	study	NOUN
fnp-3050	983	107	of	of	ADP
fnp-3050	983	108	the	the	DET
fnp-3050	983	109	brainnet	brainnet	PROPN
fnp-3050	983	110	europe	europe	PROPN
fnp-3050	983	111	consortium	consortium	PROPN
fnp-3050	983	112	.	.	PUNCT
fnp-3050	984	1	brain	brain	NOUN
fnp-3050	984	2	pathol	pathol	NOUN
fnp-3050	984	3	18:484	18:484	PROPN
fnp-3050	984	4	-	-	SYM
fnp-3050	984	5	496	496	NUM
fnp-3050	984	6	229	229	NUM
fnp-3050	984	7	.	.	PUNCT
fnp-3050	985	1	hyman	hyman	PROPN
fnp-3050	985	2	bt	bt	PROPN
fnp-3050	985	3	,	,	PUNCT
fnp-3050	985	4	phelps	phelps	PROPN
fnp-3050	985	5	ch	ch	PROPN
fnp-3050	985	6	,	,	PUNCT
fnp-3050	985	7	beach	beach	PROPN
fnp-3050	985	8	tg	tg	PROPN
fnp-3050	985	9	,	,	PUNCT
fnp-3050	985	10	bigio	bigio	NOUN
fnp-3050	985	11	eh	eh	INTJ
fnp-3050	985	12	,	,	PUNCT
fnp-3050	985	13	cairns	cairns	PROPN
fnp-3050	985	14	nj	nj	PROPN
fnp-3050	985	15	,	,	PUNCT
fnp-3050	985	16	carrillo	carrillo	PROPN
fnp-3050	985	17	mc	mc	PROPN
fnp-3050	985	18	,	,	PUNCT
fnp-3050	985	19	dickson	dickson	PROPN
fnp-3050	985	20	dw	dw	PROPN
fnp-3050	985	21	,	,	PUNCT
fnp-3050	985	22	duyckaerts	duyckaerts	PROPN
fnp-3050	985	23	c	c	PROPN
fnp-3050	985	24	,	,	PUNCT
fnp-3050	985	25	frosch	frosch	PROPN
fnp-3050	985	26	mp	mp	PROPN
fnp-3050	985	27	,	,	PUNCT
fnp-3050	985	28	masliah	masliah	PROPN
fnp-3050	985	29	e	e	PROPN
fnp-3050	985	30	,	,	PUNCT
fnp-3050	985	31	mirra	mirra	PROPN
fnp-3050	985	32	ss	ss	PROPN
fnp-3050	985	33	,	,	PUNCT
fnp-3050	985	34	nelson	nelson	PROPN
fnp-3050	985	35	pt	pt	PROPN
fnp-3050	985	36	,	,	PUNCT
fnp-3050	985	37	schneider	schneider	PROPN
fnp-3050	985	38	ja	ja	PROPN
fnp-3050	985	39	,	,	PUNCT
fnp-3050	985	40	thal	thal	PROPN
fnp-3050	985	41	dr	dr	PROPN
fnp-3050	985	42	,	,	PUNCT
fnp-3050	985	43	thies	thies	PROPN
fnp-3050	985	44	b	b	NUM
fnp-3050	985	45	,	,	PUNCT
fnp-3050	985	46	trojanowski	trojanowski	PROPN
fnp-3050	985	47	jq	jq	PROPN
fnp-3050	985	48	,	,	PUNCT
fnp-3050	985	49	vinters	vinters	PROPN
fnp-3050	985	50	hv	hv	PROPN
fnp-3050	985	51	,	,	PUNCT
fnp-3050	985	52	montine	montine	PROPN
fnp-3050	985	53	tj	tj	PROPN
fnp-3050	985	54	(	(	PUNCT
fnp-3050	985	55	2012	2012	NUM
fnp-3050	985	56	)	)	PUNCT
fnp-3050	985	57	national	national	PROPN
fnp-3050	985	58	institute	institute	NOUN
fnp-3050	985	59	on	on	ADP
fnp-3050	985	60	aging	age	VERB
fnp-3050	985	61	-	-	PUNCT
fnp-3050	985	62	alzheimer	alzheimer	NOUN
fnp-3050	985	63	's	's	PART
fnp-3050	985	64	association	association	NOUN
fnp-3050	985	65	guidelines	guideline	NOUN
fnp-3050	985	66	for	for	ADP
fnp-3050	985	67	the	the	DET
fnp-3050	985	68	neuropathologic	neuropathologic	ADJ
fnp-3050	985	69	assessment	assessment	NOUN
fnp-3050	985	70	of	of	ADP
fnp-3050	985	71	alzheimer	alzheimer	PROPN
fnp-3050	985	72	's	's	PART
fnp-3050	985	73	disease	disease	NOUN
fnp-3050	985	74	.	.	PUNCT
fnp-3050	986	1	alzheimers	alzheimers	PROPN
fnp-3050	986	2	dement	dement	PROPN
fnp-3050	986	3	8:1	8:1	NUM
fnp-3050	986	4	-	-	SYM
fnp-3050	986	5	13	13	NUM
fnp-3050	986	6	230	230	NUM
fnp-3050	986	7	.	.	PUNCT
fnp-3050	987	1	mirra	mirra	PROPN
fnp-3050	987	2	ss	ss	PROPN
fnp-3050	987	3	,	,	PUNCT
fnp-3050	987	4	heyman	heyman	PROPN
fnp-3050	987	5	a	a	PROPN
fnp-3050	987	6	,	,	PUNCT
fnp-3050	987	7	mckeel	mckeel	NOUN
fnp-3050	987	8	d	d	PROPN
fnp-3050	987	9	,	,	PUNCT
fnp-3050	987	10	sumi	sumi	NOUN
fnp-3050	987	11	sm	sm	PROPN
fnp-3050	987	12	,	,	PUNCT
fnp-3050	987	13	crain	crain	NOUN
fnp-3050	987	14	bj	bj	PROPN
fnp-3050	987	15	,	,	PUNCT
fnp-3050	987	16	brownlee	brownlee	PROPN
fnp-3050	987	17	lm	lm	PROPN
fnp-3050	987	18	,	,	PUNCT
fnp-3050	987	19	vogel	vogel	PROPN
fnp-3050	987	20	fs	fs	PROPN
fnp-3050	987	21	,	,	PUNCT
fnp-3050	987	22	hughes	hughes	PROPN
fnp-3050	987	23	jp	jp	PROPN
fnp-3050	987	24	,	,	PUNCT
fnp-3050	987	25	van	van	PROPN
fnp-3050	987	26	belle	belle	PROPN
fnp-3050	987	27	g	g	PROPN
fnp-3050	987	28	,	,	PUNCT
fnp-3050	987	29	berg	berg	PROPN
fnp-3050	987	30	l	l	PROPN
fnp-3050	987	31	(	(	PUNCT
fnp-3050	987	32	1991	1991	NUM
fnp-3050	987	33	)	)	PUNCT
fnp-3050	987	34	the	the	DET
fnp-3050	987	35	consortium	consortium	NOUN
fnp-3050	987	36	to	to	PART
fnp-3050	987	37	establish	establish	VERB
fnp-3050	987	38	a	a	DET
fnp-3050	987	39	registry	registry	NOUN
fnp-3050	987	40	for	for	ADP
fnp-3050	987	41	alzheimer	alzheimer	PROPN
fnp-3050	987	42	's	's	PART
fnp-3050	987	43	disease	disease	NOUN
fnp-3050	987	44	(	(	PUNCT
fnp-3050	987	45	cerad	cerad	PROPN
fnp-3050	987	46	)	)	PUNCT
fnp-3050	987	47	.	.	PUNCT
fnp-3050	988	1	part	part	PROPN
fnp-3050	988	2	ii	ii	PROPN
fnp-3050	988	3	.	.	PUNCT
fnp-3050	989	1	standardization	standardization	NOUN
fnp-3050	989	2	of	of	ADP
fnp-3050	989	3	the	the	DET
fnp-3050	989	4	neuropathologic	neuropathologic	ADJ
fnp-3050	989	5	assessment	assessment	NOUN
fnp-3050	989	6	of	of	ADP
fnp-3050	989	7	alzheimer	alzheimer	PROPN
fnp-3050	989	8	's	's	PART
fnp-3050	989	9	disease	disease	NOUN
fnp-3050	989	10	.	.	PUNCT
fnp-3050	990	1	neurology	neurology	NOUN
fnp-3050	990	2	41:479	41:479	PROPN
fnp-3050	990	3	-	-	PUNCT
fnp-3050	990	4	486	486	NUM
fnp-3050	990	5	231	231	NUM
fnp-3050	990	6	.	.	PUNCT
fnp-3050	991	1	braak	braak	PROPN
fnp-3050	991	2	h	h	PROPN
fnp-3050	991	3	,	,	PUNCT
fnp-3050	991	4	alafuzoff	alafuzoff	NOUN
fnp-3050	992	1	i	i	PRON
fnp-3050	992	2	,	,	PUNCT
fnp-3050	992	3	arzberger	arzberger	PROPN
fnp-3050	992	4	t	t	PROPN
fnp-3050	992	5	,	,	PUNCT
fnp-3050	992	6	kretzschmar	kretzschmar	PROPN
fnp-3050	992	7	h	h	PROPN
fnp-3050	992	8	,	,	PUNCT
fnp-3050	992	9	del	del	PROPN
fnp-3050	992	10	tredici	tredici	PROPN
fnp-3050	992	11	k	k	PROPN
fnp-3050	992	12	(	(	PUNCT
fnp-3050	992	13	2006	2006	NUM
fnp-3050	992	14	)	)	PUNCT
fnp-3050	992	15	staging	staging	NOUN
fnp-3050	992	16	of	of	ADP
fnp-3050	992	17	alzheimer	alzheimer	PROPN
fnp-3050	992	18	disease	disease	NOUN
fnp-3050	992	19	-	-	PUNCT
fnp-3050	992	20	associated	associate	VERB
fnp-3050	992	21	neurofibrillary	neurofibrillary	ADJ
fnp-3050	992	22	pathology	pathology	NOUN
fnp-3050	992	23	using	use	VERB
fnp-3050	992	24	paraffin	paraffin	NOUN
fnp-3050	992	25	sections	section	NOUN
fnp-3050	992	26	and	and	CCONJ
fnp-3050	992	27	immunocytochemistry	immunocytochemistry	NOUN
fnp-3050	992	28	.	.	PUNCT
fnp-3050	993	1	acta	acta	PROPN
fnp-3050	993	2	neuropathol	neuropathol	PROPN
fnp-3050	993	3	112:389	112:389	PROPN
fnp-3050	993	4	-	-	PUNCT
fnp-3050	993	5	404	404	NUM
fnp-3050	993	6	232	232	NUM
fnp-3050	993	7	.	.	PUNCT
fnp-3050	994	1	jellinger	jellinger	PROPN
fnp-3050	994	2	ka	ka	PROPN
fnp-3050	994	3	(	(	PUNCT
fnp-3050	994	4	2009	2009	NUM
fnp-3050	994	5	)	)	PUNCT
fnp-3050	994	6	criteria	criterion	NOUN
fnp-3050	994	7	for	for	ADP
fnp-3050	994	8	the	the	DET
fnp-3050	994	9	neuropathological	neuropathological	ADJ
fnp-3050	994	10	diagnosis	diagnosis	NOUN
fnp-3050	994	11	of	of	ADP
fnp-3050	994	12	dementing	demente	VERB
fnp-3050	994	13	disorders	disorder	NOUN
fnp-3050	994	14	:	:	PUNCT
fnp-3050	994	15	routes	route	NOUN
fnp-3050	994	16	out	out	ADP
fnp-3050	994	17	of	of	ADP
fnp-3050	994	18	the	the	DET
fnp-3050	994	19	swamp	swamp	NOUN
fnp-3050	994	20	?	?	PUNCT
fnp-3050	995	1	acta	acta	PROPN
fnp-3050	995	2	neuropathol	neuropathol	PROPN
fnp-3050	995	3	117:101	117:101	PROPN
fnp-3050	995	4	-	-	PUNCT
fnp-3050	995	5	110	110	NUM
fnp-3050	995	6	233	233	NUM
fnp-3050	995	7	.	.	PUNCT
fnp-3050	996	1	jellinger	jellinger	PROPN
fnp-3050	996	2	ka	ka	PROPN
fnp-3050	996	3	(	(	PUNCT
fnp-3050	996	4	2009	2009	NUM
fnp-3050	996	5	)	)	PUNCT
fnp-3050	996	6	a	a	DET
fnp-3050	996	7	critical	critical	ADJ
fnp-3050	996	8	evaluation	evaluation	NOUN
fnp-3050	996	9	of	of	ADP
fnp-3050	996	10	current	current	ADJ
fnp-3050	996	11	staging	staging	NOUN
fnp-3050	996	12	of	of	ADP
fnp-3050	996	13	alpha	alpha	NOUN
fnp-3050	996	14	-	-	PUNCT
fnp-3050	996	15	synuclein	synuclein	NOUN
fnp-3050	996	16	pathology	pathology	NOUN
fnp-3050	996	17	in	in	ADP
fnp-3050	996	18	lewy	lewy	ADJ
fnp-3050	996	19	body	body	NOUN
fnp-3050	996	20	disorders	disorder	NOUN
fnp-3050	996	21	.	.	PUNCT
fnp-3050	997	1	biochim	biochim	PROPN
fnp-3050	997	2	biophys	biophy	NOUN
fnp-3050	997	3	acta	acta	VERB
fnp-3050	997	4	1792:730	1792:730	NUM
fnp-3050	997	5	-	-	SYM
fnp-3050	997	6	740	740	NUM
fnp-3050	997	7	234	234	NUM
fnp-3050	997	8	.	.	PUNCT
fnp-3050	998	1	hyman	hyman	PROPN
fnp-3050	998	2	bt	bt	PROPN
fnp-3050	998	3	,	,	PUNCT
fnp-3050	998	4	trojanowski	trojanowski	PROPN
fnp-3050	998	5	jq	jq	PROPN
fnp-3050	998	6	(	(	PUNCT
fnp-3050	998	7	1997	1997	NUM
fnp-3050	998	8	)	)	PUNCT
fnp-3050	998	9	consensus	consensus	NOUN
fnp-3050	998	10	recommendations	recommendation	NOUN
fnp-3050	998	11	for	for	ADP
fnp-3050	998	12	the	the	DET
fnp-3050	998	13	postmortem	postmortem	NOUN
fnp-3050	998	14	diagnosis	diagnosis	NOUN
fnp-3050	998	15	of	of	ADP
fnp-3050	998	16	alzheimer	alzheimer	PROPN
fnp-3050	998	17	disease	disease	NOUN
fnp-3050	998	18	from	from	ADP
fnp-3050	998	19	the	the	DET
fnp-3050	998	20	national	national	PROPN
fnp-3050	998	21	institute	institute	PROPN
fnp-3050	998	22	on	on	ADP
fnp-3050	998	23	aging	aging	NOUN
fnp-3050	998	24	and	and	CCONJ
fnp-3050	998	25	the	the	DET
fnp-3050	998	26	reagan	reagan	PROPN
fnp-3050	998	27	institute	institute	PROPN
fnp-3050	998	28	working	working	PROPN
fnp-3050	998	29	group	group	NOUN
fnp-3050	998	30	on	on	ADP
fnp-3050	998	31	diagnostic	diagnostic	ADJ
fnp-3050	998	32	criteria	criterion	NOUN
fnp-3050	998	33	for	for	ADP
fnp-3050	998	34	the	the	DET
fnp-3050	998	35	neuropathological	neuropathological	ADJ
fnp-3050	998	36	assessment	assessment	NOUN
fnp-3050	998	37	of	of	ADP
fnp-3050	998	38	alzheimer	alzheimer	PROPN
fnp-3050	998	39	disease	disease	PROPN
fnp-3050	998	40	.	.	PUNCT
fnp-3050	999	1	j	j	PROPN
fnp-3050	999	2	neuropathol	neuropathol	PROPN
fnp-3050	999	3	exp	exp	PROPN
fnp-3050	999	4	neurol	neurol	PROPN
fnp-3050	999	5	56:1095	56:1095	NUM
fnp-3050	999	6	-	-	NUM
fnp-3050	999	7	1097	1097	NUM
fnp-3050	999	8	235	235	NUM
fnp-3050	999	9	.	.	PUNCT
fnp-3050	999	10	bowler	bowler	NOUN
fnp-3050	999	11	jv	jv	PROPN
fnp-3050	999	12	,	,	PUNCT
fnp-3050	999	13	munoz	munoz	PROPN
fnp-3050	999	14	dg	dg	PROPN
fnp-3050	999	15	,	,	PUNCT
fnp-3050	999	16	merskey	merskey	PROPN
fnp-3050	999	17	h	h	NOUN
fnp-3050	999	18	,	,	PUNCT
fnp-3050	999	19	hachinski	hachinski	NOUN
fnp-3050	999	20	v	v	PROPN
fnp-3050	999	21	(	(	PUNCT
fnp-3050	999	22	1998	1998	NUM
fnp-3050	999	23	)	)	PUNCT
fnp-3050	999	24	fallacies	fallacy	NOUN
fnp-3050	999	25	in	in	ADP
fnp-3050	999	26	the	the	DET
fnp-3050	999	27	pathological	pathological	ADJ
fnp-3050	999	28	confirmation	confirmation	NOUN
fnp-3050	999	29	of	of	ADP
fnp-3050	999	30	the	the	DET
fnp-3050	999	31	diagnosis	diagnosis	NOUN
fnp-3050	999	32	of	of	ADP
fnp-3050	999	33	alzheimer	alzheimer	PROPN
fnp-3050	999	34	's	's	PART
fnp-3050	999	35	disease	disease	NOUN
fnp-3050	999	36	.	.	PUNCT
fnp-3050	1000	1	j	j	PROPN
fnp-3050	1000	2	neurol	neurol	PROPN
fnp-3050	1000	3	neurosurg	neurosurg	PROPN
fnp-3050	1000	4	psychiatry	psychiatry	PROPN
fnp-3050	1000	5	64:18	64:18	NUM
fnp-3050	1000	6	-	-	SYM
fnp-3050	1000	7	24	24	NUM
fnp-3050	1000	8	.	.	PUNCT
fnp-3050	1000	9	236	236	NUM
fnp-3050	1000	10	.	.	PUNCT
fnp-3050	1000	11	beach	beach	PROPN
fnp-3050	1000	12	tg	tg	PROPN
fnp-3050	1000	13	,	,	PUNCT
fnp-3050	1000	14	monsell	monsell	PROPN
fnp-3050	1000	15	se	se	X
fnp-3050	1000	16	,	,	PUNCT
fnp-3050	1000	17	phillips	phillips	PROPN
fnp-3050	1000	18	le	le	PROPN
fnp-3050	1000	19	,	,	PUNCT
fnp-3050	1000	20	kukull	kukull	PROPN
fnp-3050	1000	21	w	w	PROPN
fnp-3050	1000	22	(	(	PUNCT
fnp-3050	1000	23	2012	2012	NUM
fnp-3050	1000	24	)	)	PUNCT
fnp-3050	1000	25	accuracy	accuracy	NOUN
fnp-3050	1000	26	of	of	ADP
fnp-3050	1000	27	the	the	DET
fnp-3050	1000	28	clinical	clinical	ADJ
fnp-3050	1000	29	diagnosis	diagnosis	NOUN
fnp-3050	1000	30	of	of	ADP
fnp-3050	1000	31	alzheimer	alzheimer	PROPN
fnp-3050	1000	32	disease	disease	NOUN
fnp-3050	1000	33	at	at	ADP
fnp-3050	1000	34	national	national	PROPN
fnp-3050	1000	35	institute	institute	PROPN
fnp-3050	1000	36	on	on	ADP
fnp-3050	1000	37	aging	age	VERB
fnp-3050	1000	38	alzheimer	alzheimer	NOUN
fnp-3050	1000	39	disease	disease	NOUN
fnp-3050	1000	40	centers	center	NOUN
fnp-3050	1000	41	,	,	PUNCT
fnp-3050	1000	42	2005	2005	NUM
fnp-3050	1000	43	-	-	SYM
fnp-3050	1000	44	2010	2010	NUM
fnp-3050	1000	45	.	.	PUNCT
fnp-3050	1001	1	j	j	PROPN
fnp-3050	1001	2	neuropathol	neuropathol	PROPN
fnp-3050	1001	3	exp	exp	PROPN
fnp-3050	1001	4	neurol	neurol	PROPN
fnp-3050	1001	5	71:266	71:266	PROPN
fnp-3050	1001	6	-	-	PUNCT
fnp-3050	1001	7	273	273	NUM
fnp-3050	1001	8	237	237	NUM
fnp-3050	1001	9	.	.	PUNCT
fnp-3050	1002	1	montine	montine	PROPN
fnp-3050	1002	2	tj	tj	PROPN
fnp-3050	1002	3	,	,	PUNCT
fnp-3050	1002	4	monsell	monsell	ADJ
fnp-3050	1002	5	se	se	X
fnp-3050	1002	6	,	,	PUNCT
fnp-3050	1002	7	beach	beach	PROPN
fnp-3050	1002	8	tg	tg	PROPN
fnp-3050	1002	9	,	,	PUNCT
fnp-3050	1002	10	bigio	bigio	NOUN
fnp-3050	1002	11	eh	eh	INTJ
fnp-3050	1002	12	,	,	PUNCT
fnp-3050	1002	13	bu	bu	PROPN
fnp-3050	1002	14	y	y	PROPN
fnp-3050	1002	15	,	,	PUNCT
fnp-3050	1002	16	cairns	cairns	PROPN
fnp-3050	1002	17	nj	nj	PROPN
fnp-3050	1002	18	,	,	PUNCT
fnp-3050	1002	19	frosch	frosch	PROPN
fnp-3050	1002	20	m	m	PROPN
fnp-3050	1002	21	,	,	PUNCT
fnp-3050	1002	22	henriksen	henriksen	PROPN
fnp-3050	1002	23	j	j	PROPN
fnp-3050	1002	24	,	,	PUNCT
fnp-3050	1002	25	kofler	kofler	PROPN
fnp-3050	1002	26	j	j	PROPN
fnp-3050	1002	27	,	,	PUNCT
fnp-3050	1002	28	kukull	kukull	PROPN
fnp-3050	1002	29	wa	wa	PROPN
fnp-3050	1002	30	,	,	PUNCT
fnp-3050	1002	31	lee	lee	PROPN
fnp-3050	1002	32	eb	eb	PROPN
fnp-3050	1002	33	,	,	PUNCT
fnp-3050	1002	34	nelson	nelson	PROPN
fnp-3050	1002	35	pt	pt	PROPN
fnp-3050	1002	36	,	,	PUNCT
fnp-3050	1002	37	schantz	schantz	PROPN
fnp-3050	1002	38	am	be	AUX
fnp-3050	1002	39	,	,	PUNCT
fnp-3050	1002	40	schneider	schneider	PROPN
fnp-3050	1002	41	ja	ja	PROPN
fnp-3050	1002	42	,	,	PUNCT
fnp-3050	1002	43	sonnen	sonnen	PROPN
fnp-3050	1002	44	ja	ja	PROPN
fnp-3050	1002	45	,	,	PUNCT
fnp-3050	1002	46	trojanowski	trojanowski	PROPN
fnp-3050	1002	47	jq	jq	PROPN
fnp-3050	1002	48	,	,	PUNCT
fnp-3050	1002	49	vinters	vinters	PROPN
fnp-3050	1002	50	hv	hv	PROPN
fnp-3050	1002	51	,	,	PUNCT
fnp-3050	1002	52	zhou	zhou	PROPN
fnp-3050	1002	53	xh	xh	PROPN
fnp-3050	1002	54	,	,	PUNCT
fnp-3050	1002	55	hyman	hyman	PROPN
fnp-3050	1002	56	bt	bt	PROPN
fnp-3050	1002	57	(	(	PUNCT
fnp-3050	1002	58	2016	2016	NUM
fnp-3050	1002	59	)	)	PUNCT
fnp-3050	1002	60	multisite	multisite	ADJ
fnp-3050	1002	61	assessment	assessment	NOUN
fnp-3050	1002	62	of	of	ADP
fnp-3050	1002	63	nia	nia	PROPN
fnp-3050	1002	64	-	-	PUNCT
fnp-3050	1002	65	aa	aa	PROPN
fnp-3050	1002	66	guidelines	guideline	NOUN
fnp-3050	1002	67	for	for	ADP
fnp-3050	1002	68	the	the	DET
fnp-3050	1002	69	neuropathologic	neuropathologic	ADJ
fnp-3050	1002	70	evaluation	evaluation	NOUN
fnp-3050	1002	71	of	of	ADP
fnp-3050	1002	72	alzheimer	alzheimer	PROPN
fnp-3050	1002	73	's	's	PART
fnp-3050	1002	74	disease	disease	NOUN
fnp-3050	1002	75	.	.	PUNCT
fnp-3050	1003	1	alzheimers	alzheimers	PROPN
fnp-3050	1003	2	dement	dement	PROPN
fnp-3050	1003	3	12:164	12:164	PROPN
fnp-3050	1003	4	-	-	SYM
fnp-3050	1003	5	169	169	NUM
fnp-3050	1003	6	238	238	NUM
fnp-3050	1003	7	.	.	PUNCT
fnp-3050	1004	1	plassman	plassman	PROPN
fnp-3050	1004	2	bl	bl	PROPN
fnp-3050	1004	3	,	,	PUNCT
fnp-3050	1004	4	khachaturian	khachaturian	X
fnp-3050	1004	5	as	as	ADP
fnp-3050	1004	6	,	,	PUNCT
fnp-3050	1004	7	townsend	townsend	PROPN
fnp-3050	1004	8	jj	jj	PROPN
fnp-3050	1004	9	,	,	PUNCT
fnp-3050	1004	10	ball	ball	PROPN
fnp-3050	1004	11	mj	mj	PROPN
fnp-3050	1004	12	,	,	PUNCT
fnp-3050	1004	13	steffens	steffen	VERB
fnp-3050	1004	14	dc	dc	PROPN
fnp-3050	1004	15	,	,	PUNCT
fnp-3050	1004	16	leslie	leslie	PROPN
fnp-3050	1004	17	ce	ce	PROPN
fnp-3050	1004	18	,	,	PUNCT
fnp-3050	1004	19	tschanz	tschanz	PROPN
fnp-3050	1004	20	jt	jt	PROPN
fnp-3050	1004	21	,	,	PUNCT
fnp-3050	1004	22	norton	norton	PROPN
fnp-3050	1004	23	mc	mc	PROPN
fnp-3050	1004	24	,	,	PUNCT
fnp-3050	1004	25	burke	burke	PROPN
fnp-3050	1004	26	jr	jr	PROPN
fnp-3050	1004	27	,	,	PUNCT
fnp-3050	1004	28	welsh	welsh	PROPN
fnp-3050	1004	29	-	-	PUNCT
fnp-3050	1004	30	bohmer	bohmer	PROPN
fnp-3050	1004	31	ka	ka	PROPN
fnp-3050	1004	32	,	,	PUNCT
fnp-3050	1004	33	hulette	hulette	PROPN
fnp-3050	1004	34	cm	cm	PROPN
fnp-3050	1004	35	,	,	PUNCT
fnp-3050	1004	36	nixon	nixon	PROPN
fnp-3050	1004	37	rr	rr	PROPN
fnp-3050	1004	38	,	,	PUNCT
fnp-3050	1004	39	tyrey	tyrey	PROPN
fnp-3050	1004	40	m	m	PROPN
fnp-3050	1004	41	,	,	PUNCT
fnp-3050	1004	42	breitner	breitner	NOUN
fnp-3050	1004	43	jc	jc	PROPN
fnp-3050	1004	44	(	(	PUNCT
fnp-3050	1004	45	2006	2006	NUM
fnp-3050	1004	46	)	)	PUNCT
fnp-3050	1004	47	comparison	comparison	NOUN
fnp-3050	1004	48	of	of	ADP
fnp-3050	1004	49	clinical	clinical	ADJ
fnp-3050	1004	50	and	and	CCONJ
fnp-3050	1004	51	neuropathologic	neuropathologic	ADJ
fnp-3050	1004	52	diagnoses	diagnosis	NOUN
fnp-3050	1004	53	of	of	ADP
fnp-3050	1004	54	alzheimer	alzheimer	PROPN
fnp-3050	1004	55	's	's	PART
fnp-3050	1004	56	disease	disease	NOUN
fnp-3050	1004	57	in	in	ADP
fnp-3050	1004	58	3	3	NUM
fnp-3050	1004	59	epidemiologic	epidemiologic	ADJ
fnp-3050	1004	60	samples	sample	NOUN
fnp-3050	1004	61	.	.	PUNCT
fnp-3050	1005	1	alzheimers	alzheimer	NOUN
fnp-3050	1005	2	dement	dement	PROPN
fnp-3050	1005	3	2:2	2:2	NUM
fnp-3050	1005	4	-	-	SYM
fnp-3050	1005	5	11	11	NUM
fnp-3050	1005	6	239	239	NUM
fnp-3050	1005	7	.	.	PUNCT
fnp-3050	1006	1	cure	cure	PROPN
fnp-3050	1006	2	s	s	PROPN
fnp-3050	1006	3	,	,	PUNCT
fnp-3050	1006	4	abrams	abrams	PROPN
fnp-3050	1006	5	k	k	PROPN
fnp-3050	1006	6	,	,	PUNCT
fnp-3050	1006	7	belger	belg	ADJ
fnp-3050	1006	8	m	m	PROPN
fnp-3050	1006	9	,	,	PUNCT
fnp-3050	1006	10	dell'agnello	dell'agnello	PROPN
fnp-3050	1006	11	g	g	PROPN
fnp-3050	1006	12	,	,	PUNCT
fnp-3050	1006	13	happich	happich	NOUN
fnp-3050	1006	14	m	m	PROPN
fnp-3050	1006	15	(	(	PUNCT
fnp-3050	1006	16	2014	2014	NUM
fnp-3050	1006	17	)	)	PUNCT
fnp-3050	1006	18	systematic	systematic	ADJ
fnp-3050	1006	19	literature	literature	NOUN
fnp-3050	1006	20	review	review	NOUN
fnp-3050	1006	21	and	and	CCONJ
fnp-3050	1006	22	meta	meta	NOUN
fnp-3050	1006	23	-	-	PUNCT
fnp-3050	1006	24	analysis	analysis	NOUN
fnp-3050	1006	25	of	of	ADP
fnp-3050	1006	26	diagnostic	diagnostic	ADJ
fnp-3050	1006	27	test	test	NOUN
fnp-3050	1006	28	accuracy	accuracy	NOUN
fnp-3050	1006	29	in	in	ADP
fnp-3050	1006	30	alzheimer	alzheimer	PROPN
fnp-3050	1006	31	's	's	PART
fnp-3050	1006	32	disease	disease	NOUN
fnp-3050	1006	33	and	and	CCONJ
fnp-3050	1006	34	other	other	ADJ
fnp-3050	1006	35	dementia	dementia	NOUN
fnp-3050	1006	36	using	use	VERB
fnp-3050	1006	37	autopsy	autopsy	ADJ
fnp-3050	1006	38	as	as	ADP
fnp-3050	1006	39	standard	standard	NOUN
fnp-3050	1006	40	of	of	ADP
fnp-3050	1006	41	truth	truth	NOUN
fnp-3050	1006	42	.	.	PUNCT
fnp-3050	1007	1	j	j	PROPN
fnp-3050	1007	2	alzheimers	alzheimers	PROPN
fnp-3050	1007	3	dis	dis	PROPN
fnp-3050	1007	4	42:169	42:169	NUM
fnp-3050	1007	5	-	-	SYM
fnp-3050	1007	6	182	182	NUM
fnp-3050	1007	7	240	240	NUM
fnp-3050	1007	8	.	.	PUNCT
fnp-3050	1008	1	janocko	janocko	PROPN
fnp-3050	1008	2	nj	nj	PROPN
fnp-3050	1008	3	,	,	PUNCT
fnp-3050	1008	4	brodersen	brodersen	PROPN
fnp-3050	1008	5	ka	ka	PROPN
fnp-3050	1008	6	,	,	PUNCT
fnp-3050	1008	7	soto	soto	PROPN
fnp-3050	1008	8	-	-	PUNCT
fnp-3050	1008	9	ortolaza	ortolaza	PROPN
fnp-3050	1008	10	ai	ai	VERB
fnp-3050	1008	11	,	,	PUNCT
fnp-3050	1008	12	ross	ross	PROPN
fnp-3050	1008	13	oa	oa	PRON
fnp-3050	1008	14	,	,	PUNCT
fnp-3050	1008	15	liesinger	liesinger	NOUN
fnp-3050	1008	16	am	be	AUX
fnp-3050	1008	17	,	,	PUNCT
fnp-3050	1008	18	duara	duara	NOUN
fnp-3050	1008	19	r	r	NOUN
fnp-3050	1008	20	,	,	PUNCT
fnp-3050	1008	21	graff	graff	NOUN
fnp-3050	1008	22	-	-	PUNCT
fnp-3050	1008	23	radford	radford	PROPN
fnp-3050	1008	24	nr	nr	PROPN
fnp-3050	1008	25	,	,	PUNCT
fnp-3050	1008	26	dickson	dickson	PROPN
fnp-3050	1008	27	dw	dw	PROPN
fnp-3050	1008	28	,	,	PUNCT
fnp-3050	1008	29	murray	murray	VERB
fnp-3050	1008	30	me	i	PRON
fnp-3050	1008	31	(	(	PUNCT
fnp-3050	1008	32	2012	2012	NUM
fnp-3050	1008	33	)	)	PUNCT
fnp-3050	1009	1	neuropathologically	neuropathologically	ADV
fnp-3050	1009	2	defined	define	VERB
fnp-3050	1009	3	subtypes	subtype	NOUN
fnp-3050	1009	4	of	of	ADP
fnp-3050	1009	5	alzheimer	alzheimer	PROPN
fnp-3050	1009	6	's	's	PART
fnp-3050	1009	7	disease	disease	NOUN
fnp-3050	1009	8	differ	differ	VERB
fnp-3050	1009	9	significantly	significantly	ADV
fnp-3050	1009	10	from	from	ADP
fnp-3050	1009	11	neurofibrillary	neurofibrillary	ADJ
fnp-3050	1009	12	tangle	tangle	NOUN
fnp-3050	1009	13	-	-	PUNCT
fnp-3050	1009	14	predominant	predominant	ADJ
fnp-3050	1009	15	dementia	dementia	NOUN
fnp-3050	1009	16	.	.	PUNCT
fnp-3050	1010	1	acta	acta	PROPN
fnp-3050	1010	2	neuropathol	neuropathol	PROPN
fnp-3050	1010	3	124:681	124:681	NUM
fnp-3050	1010	4	-	-	SYM
fnp-3050	1010	5	692	692	NUM
fnp-3050	1010	6	241	241	NUM
fnp-3050	1010	7	.	.	PUNCT
fnp-3050	1011	1	jellinger	jellinger	PROPN
fnp-3050	1011	2	ka	ka	PROPN
fnp-3050	1011	3	(	(	PUNCT
fnp-3050	1011	4	2014	2014	NUM
fnp-3050	1011	5	)	)	PUNCT
fnp-3050	1011	6	alzheimer	alzheimer	PROPN
fnp-3050	1011	7	’s	’s	PART
fnp-3050	1011	8	disease	disease	NOUN
fnp-3050	1011	9	:	:	PUNCT
fnp-3050	1011	10	current	current	ADJ
fnp-3050	1011	11	clinical	clinical	ADJ
fnp-3050	1011	12	and	and	CCONJ
fnp-3050	1011	13	neuropathologic	neuropathologic	ADJ
fnp-3050	1011	14	diagnostic	diagnostic	ADJ
fnp-3050	1011	15	criteria	criterion	NOUN
fnp-3050	1011	16	.	.	PUNCT
fnp-3050	1012	1	austin	austin	PROPN
fnp-3050	1012	2	alzheimers	alzheimers	PROPN
fnp-3050	1012	3	j	j	PROPN
fnp-3050	1012	4	parkinsons	parkinson	NOUN
fnp-3050	1012	5	dis	dis	PROPN
fnp-3050	1012	6	1:6	1:6	NUM
fnp-3050	1012	7	242	242	NUM
fnp-3050	1012	8	.	.	PUNCT
fnp-3050	1013	1	murray	murray	VERB
fnp-3050	1013	2	me	i	PRON
fnp-3050	1013	3	,	,	PUNCT
fnp-3050	1013	4	cannon	cannon	NOUN
fnp-3050	1013	5	a	a	DET
fnp-3050	1013	6	,	,	PUNCT
fnp-3050	1013	7	graff	graff	NOUN
fnp-3050	1013	8	-	-	PUNCT
fnp-3050	1013	9	radford	radford	PROPN
fnp-3050	1013	10	nr	nr	PROPN
fnp-3050	1013	11	,	,	PUNCT
fnp-3050	1013	12	liesinger	liesinger	ADJ
fnp-3050	1013	13	am	be	AUX
fnp-3050	1013	14	,	,	PUNCT
fnp-3050	1013	15	rutherford	rutherford	PROPN
fnp-3050	1013	16	nj	nj	PROPN
fnp-3050	1013	17	,	,	PUNCT
fnp-3050	1013	18	ross	ross	PROPN
fnp-3050	1013	19	oa	oa	PRON
fnp-3050	1013	20	,	,	PUNCT
fnp-3050	1013	21	duara	duara	PROPN
fnp-3050	1013	22	r	r	PROPN
fnp-3050	1013	23	,	,	PUNCT
fnp-3050	1013	24	carrasquillo	carrasquillo	NOUN
fnp-3050	1013	25	mm	mm	PROPN
fnp-3050	1013	26	,	,	PUNCT
fnp-3050	1013	27	rademakers	rademaker	NOUN
fnp-3050	1013	28	r	r	NOUN
fnp-3050	1013	29	,	,	PUNCT
fnp-3050	1013	30	dickson	dickson	PROPN
fnp-3050	1013	31	dw	dw	PROPN
fnp-3050	1013	32	(	(	PUNCT
fnp-3050	1013	33	2014	2014	NUM
fnp-3050	1013	34	)	)	PUNCT
fnp-3050	1013	35	differential	differential	ADJ
fnp-3050	1013	36	clinicopathologic	clinicopathologic	ADJ
fnp-3050	1013	37	and	and	CCONJ
fnp-3050	1013	38	genetic	genetic	ADJ
fnp-3050	1013	39	features	feature	NOUN
fnp-3050	1013	40	of	of	ADP
fnp-3050	1013	41	late	late	ADJ
fnp-3050	1013	42	-	-	PUNCT
fnp-3050	1013	43	onset	onset	NOUN
fnp-3050	1013	44	amnestic	amnestic	ADJ
fnp-3050	1013	45	dementias	dementia	NOUN
fnp-3050	1013	46	.	.	PUNCT
fnp-3050	1014	1	acta	acta	PROPN
fnp-3050	1014	2	neuropathol	neuropathol	PROPN
fnp-3050	1014	3	128:411	128:411	PROPN
fnp-3050	1014	4	-	-	PUNCT
fnp-3050	1014	5	421	421	NUM
fnp-3050	1014	6	243	243	NUM
fnp-3050	1014	7	.	.	PUNCT
fnp-3050	1015	1	tiraboschi	tiraboschi	PROPN
fnp-3050	1016	1	p	p	X
fnp-3050	1016	2	,	,	PUNCT
fnp-3050	1016	3	sabbagh	sabbagh	PROPN
fnp-3050	1016	4	mn	mn	PROPN
fnp-3050	1016	5	,	,	PUNCT
fnp-3050	1016	6	hansen	hansen	PROPN
fnp-3050	1016	7	la	la	PROPN
fnp-3050	1016	8	,	,	PUNCT
fnp-3050	1016	9	salmon	salmon	NOUN
fnp-3050	1016	10	dp	dp	NOUN
fnp-3050	1016	11	,	,	PUNCT
fnp-3050	1016	12	merdes	merdes	ADV
fnp-3050	1016	13	a	a	PRON
fnp-3050	1016	14	,	,	PUNCT
fnp-3050	1016	15	gamst	gamst	VERB
fnp-3050	1016	16	a	a	PRON
fnp-3050	1016	17	,	,	PUNCT
fnp-3050	1016	18	masliah	masliah	PROPN
fnp-3050	1016	19	e	e	NOUN
fnp-3050	1016	20	,	,	PUNCT
fnp-3050	1016	21	alford	alford	PROPN
fnp-3050	1016	22	m	m	PROPN
fnp-3050	1016	23	,	,	PUNCT
fnp-3050	1016	24	thal	thal	PROPN
fnp-3050	1016	25	lj	lj	PROPN
fnp-3050	1016	26	,	,	PUNCT
fnp-3050	1016	27	corey	corey	PROPN
fnp-3050	1016	28	-	-	PUNCT
fnp-3050	1016	29	bloom	bloom	PROPN
fnp-3050	1016	30	j	j	PROPN
fnp-3050	1016	31	(	(	PUNCT
fnp-3050	1016	32	2004	2004	NUM
fnp-3050	1016	33	)	)	PUNCT
fnp-3050	1016	34	alzheimer	alzheimer	NOUN
fnp-3050	1016	35	disease	disease	NOUN
fnp-3050	1016	36	without	without	ADP
fnp-3050	1016	37	neocortical	neocortical	ADJ
fnp-3050	1016	38	neurofibrillary	neurofibrillary	ADJ
fnp-3050	1016	39	tangles	tangle	NOUN
fnp-3050	1016	40	:	:	PUNCT
fnp-3050	1016	41	"	"	PUNCT
fnp-3050	1016	42	a	a	DET
fnp-3050	1016	43	second	second	ADJ
fnp-3050	1016	44	look	look	NOUN
fnp-3050	1016	45	"	"	PUNCT
fnp-3050	1016	46	.	.	PUNCT
fnp-3050	1017	1	neurology	neurology	NOUN
fnp-3050	1017	2	62:1141	62:1141	NOUN
fnp-3050	1017	3	-	-	SYM
fnp-3050	1017	4	1147	1147	NUM
fnp-3050	1017	5	244	244	NUM
fnp-3050	1017	6	.	.	PUNCT
fnp-3050	1018	1	hansen	hansen	PROPN
fnp-3050	1018	2	l	l	PROPN
fnp-3050	1018	3	,	,	PUNCT
fnp-3050	1018	4	salmon	salmon	NOUN
fnp-3050	1018	5	d	d	NOUN
fnp-3050	1018	6	,	,	PUNCT
fnp-3050	1018	7	galasko	galasko	PROPN
fnp-3050	1018	8	d	d	PROPN
fnp-3050	1018	9	,	,	PUNCT
fnp-3050	1018	10	masliah	masliah	PROPN
fnp-3050	1018	11	e	e	PROPN
fnp-3050	1018	12	,	,	PUNCT
fnp-3050	1018	13	katzman	katzman	PROPN
fnp-3050	1018	14	r	r	NOUN
fnp-3050	1018	15	,	,	PUNCT
fnp-3050	1018	16	deteresa	deteresa	NOUN
fnp-3050	1018	17	r	r	NOUN
fnp-3050	1018	18	,	,	PUNCT
fnp-3050	1018	19	thal	thal	PROPN
fnp-3050	1018	20	l	l	PROPN
fnp-3050	1018	21	,	,	PUNCT
fnp-3050	1018	22	pay	pay	VERB
fnp-3050	1018	23	mm	mm	PROPN
fnp-3050	1018	24	,	,	PUNCT
fnp-3050	1018	25	hofstetter	hofstetter	NOUN
fnp-3050	1018	26	r	r	PROPN
fnp-3050	1018	27	,	,	PUNCT
fnp-3050	1018	28	klauber	klauber	NOUN
fnp-3050	1018	29	m	m	PROPN
fnp-3050	1018	30	,	,	PUNCT
fnp-3050	1018	31	et	et	PROPN
fnp-3050	1018	32	al	al	PROPN
fnp-3050	1018	33	.	.	PROPN
fnp-3050	1019	1	(	(	PUNCT
fnp-3050	1019	2	1990	1990	NUM
fnp-3050	1019	3	)	)	PUNCT
fnp-3050	1019	4	the	the	DET
fnp-3050	1019	5	lewy	lewy	PROPN
fnp-3050	1019	6	body	body	NOUN
fnp-3050	1019	7	variant	variant	NOUN
fnp-3050	1019	8	of	of	ADP
fnp-3050	1019	9	alzheimer	alzheimer	PROPN
fnp-3050	1019	10	's	's	PART
fnp-3050	1019	11	disease	disease	NOUN
fnp-3050	1019	12	:	:	PUNCT
fnp-3050	1019	13	a	a	DET
fnp-3050	1019	14	clinical	clinical	ADJ
fnp-3050	1019	15	and	and	CCONJ
fnp-3050	1019	16	pathologic	pathologic	ADJ
fnp-3050	1019	17	entity	entity	NOUN
fnp-3050	1019	18	.	.	PUNCT
fnp-3050	1020	1	neurology	neurology	NOUN
fnp-3050	1020	2	40:1	40:1	PROPN
fnp-3050	1020	3	-	-	SYM
fnp-3050	1020	4	8	8	NUM
fnp-3050	1020	5	.	.	NUM
fnp-3050	1020	6	245	245	NUM
fnp-3050	1020	7	.	.	PUNCT
fnp-3050	1021	1	crary	crary	PROPN
fnp-3050	1021	2	jf	jf	PROPN
fnp-3050	1021	3	,	,	PUNCT
fnp-3050	1021	4	trojanowski	trojanowski	PROPN
fnp-3050	1021	5	jq	jq	PROPN
fnp-3050	1021	6	,	,	PUNCT
fnp-3050	1021	7	schneider	schneider	PROPN
fnp-3050	1021	8	ja	ja	PROPN
fnp-3050	1021	9	,	,	PUNCT
fnp-3050	1021	10	abisambra	abisambra	VERB
fnp-3050	1021	11	jf	jf	PROPN
fnp-3050	1021	12	,	,	PUNCT
fnp-3050	1021	13	abner	abner	PROPN
fnp-3050	1021	14	el	el	PROPN
fnp-3050	1021	15	,	,	PUNCT
fnp-3050	1021	16	alafuzoff	alafuzoff	NOUN
fnp-3050	1022	1	i	i	PRON
fnp-3050	1022	2	,	,	PUNCT
fnp-3050	1022	3	arnold	arnold	PROPN
fnp-3050	1022	4	se	se	PROPN
fnp-3050	1022	5	,	,	PUNCT
fnp-3050	1022	6	attems	attem	VERB
fnp-3050	1022	7	j	j	PROPN
fnp-3050	1022	8	,	,	PUNCT
fnp-3050	1022	9	beach	beach	PROPN
fnp-3050	1022	10	tg	tg	PROPN
fnp-3050	1022	11	,	,	PUNCT
fnp-3050	1022	12	bigio	bigio	NOUN
fnp-3050	1022	13	eh	eh	INTJ
fnp-3050	1022	14	,	,	PUNCT
fnp-3050	1022	15	cairns	cairns	PROPN
fnp-3050	1022	16	nj	nj	PROPN
fnp-3050	1022	17	,	,	PUNCT
fnp-3050	1022	18	dickson	dickson	PROPN
fnp-3050	1022	19	dw	dw	PROPN
fnp-3050	1022	20	,	,	PUNCT
fnp-3050	1022	21	gearing	gear	VERB
fnp-3050	1022	22	m	m	PRON
fnp-3050	1022	23	,	,	PUNCT
fnp-3050	1022	24	grinberg	grinberg	PROPN
fnp-3050	1022	25	lt	lt	PROPN
fnp-3050	1022	26	,	,	PUNCT
fnp-3050	1022	27	hof	hof	PROPN
fnp-3050	1022	28	pr	pr	PROPN
fnp-3050	1022	29	,	,	PUNCT
fnp-3050	1022	30	hyman	hyman	PROPN
fnp-3050	1022	31	bt	bt	PROPN
fnp-3050	1022	32	,	,	PUNCT
fnp-3050	1022	33	jellinger	jellinger	PROPN
fnp-3050	1022	34	k	k	PROPN
fnp-3050	1022	35	,	,	PUNCT
fnp-3050	1022	36	jicha	jicha	PROPN
fnp-3050	1022	37	ga	ga	PROPN
fnp-3050	1022	38	,	,	PUNCT
fnp-3050	1022	39	kovacs	kovacs	PROPN
fnp-3050	1022	40	gg	gg	PROPN
fnp-3050	1022	41	,	,	PUNCT
fnp-3050	1022	42	knopman	knopman	NOUN
fnp-3050	1022	43	ds	ds	PROPN
fnp-3050	1022	44	,	,	PUNCT
fnp-3050	1022	45	kofler	kofler	PROPN
fnp-3050	1022	46	j	j	PROPN
fnp-3050	1022	47	,	,	PUNCT
fnp-3050	1022	48	kukull	kukull	PROPN
fnp-3050	1022	49	wa	wa	PROPN
fnp-3050	1022	50	,	,	PUNCT
fnp-3050	1022	51	mackenzie	mackenzie	PROPN
fnp-3050	1022	52	ir	ir	PROPN
fnp-3050	1022	53	,	,	PUNCT
fnp-3050	1022	54	masliah	masliah	PROPN
fnp-3050	1022	55	e	e	PROPN
fnp-3050	1022	56	,	,	PUNCT
fnp-3050	1022	57	mckee	mckee	PROPN
fnp-3050	1022	58	a	a	DET
fnp-3050	1022	59	,	,	PUNCT
fnp-3050	1022	60	montine	montine	PROPN
fnp-3050	1022	61	tj	tj	PROPN
fnp-3050	1022	62	,	,	PUNCT
fnp-3050	1022	63	murray	murray	VERB
fnp-3050	1022	64	me	i	PRON
fnp-3050	1022	65	,	,	PUNCT
fnp-3050	1022	66	neltner	neltner	PROPN
fnp-3050	1022	67	jh	jh	PROPN
fnp-3050	1022	68	,	,	PUNCT
fnp-3050	1022	69	santa	santa	PROPN
fnp-3050	1022	70	-	-	PUNCT
fnp-3050	1022	71	maria	maria	PROPN
fnp-3050	1022	72	i	i	PROPN
fnp-3050	1022	73	,	,	PUNCT
fnp-3050	1022	74	seeley	seeley	PROPN
fnp-3050	1022	75	ww	ww	PROPN
fnp-3050	1022	76	,	,	PUNCT
fnp-3050	1022	77	serrano	serrano	PROPN
fnp-3050	1022	78	-	-	PUNCT
fnp-3050	1022	79	pozo	pozo	PROPN
fnp-3050	1022	80	a	a	PRON
fnp-3050	1022	81	,	,	PUNCT
fnp-3050	1022	82	shelanski	shelanski	ADJ
fnp-3050	1022	83	ml	ml	ADP
fnp-3050	1022	84	,	,	PUNCT
fnp-3050	1022	85	stein	stein	PROPN
fnp-3050	1022	86	t	t	PROPN
fnp-3050	1022	87	,	,	PUNCT
fnp-3050	1022	88	takao	takao	PROPN
fnp-3050	1022	89	m	m	PROPN
fnp-3050	1022	90	,	,	PUNCT
fnp-3050	1022	91	thal	thal	PROPN
fnp-3050	1022	92	dr	dr	PROPN
fnp-3050	1022	93	,	,	PUNCT
fnp-3050	1022	94	toledo	toledo	PROPN
fnp-3050	1022	95	jb	jb	PROPN
fnp-3050	1022	96	,	,	PUNCT
fnp-3050	1022	97	troncoso	troncoso	PROPN
fnp-3050	1022	98	jc	jc	PROPN
fnp-3050	1022	99	,	,	PUNCT
fnp-3050	1023	1	vonsattel	vonsattel	PROPN
fnp-3050	1023	2	jp	jp	PROPN
fnp-3050	1023	3	,	,	PUNCT
fnp-3050	1023	4	white	white	ADJ
fnp-3050	1023	5	cl	cl	NOUN
fnp-3050	1023	6	,	,	PUNCT
fnp-3050	1023	7	3rd	3rd	NOUN
fnp-3050	1023	8	,	,	PUNCT
fnp-3050	1023	9	wisniewski	wisniewski	PROPN
fnp-3050	1023	10	t	t	PROPN
fnp-3050	1023	11	,	,	PUNCT
fnp-3050	1023	12	woltjer	woltjer	ADJ
fnp-3050	1023	13	rl	rl	PROPN
fnp-3050	1023	14	,	,	PUNCT
fnp-3050	1023	15	yamada	yamada	PROPN
fnp-3050	1023	16	m	m	PROPN
fnp-3050	1023	17	,	,	PUNCT
fnp-3050	1023	18	nelson	nelson	PROPN
fnp-3050	1023	19	pt	pt	PROPN
fnp-3050	1023	20	(	(	PUNCT
fnp-3050	1023	21	2014	2014	NUM
fnp-3050	1023	22	)	)	PUNCT
fnp-3050	1023	23	primary	primary	ADJ
fnp-3050	1023	24	age	age	NOUN
fnp-3050	1023	25	-	-	PUNCT
fnp-3050	1023	26	related	relate	VERB
fnp-3050	1023	27	tauopathy	tauopathy	NOUN
fnp-3050	1023	28	(	(	PUNCT
fnp-3050	1023	29	part	part	NOUN
fnp-3050	1023	30	):	):	PUNCT
fnp-3050	1023	31	a	a	DET
fnp-3050	1023	32	common	common	ADJ
fnp-3050	1023	33	pathology	pathology	NOUN
fnp-3050	1023	34	associated	associate	VERB
fnp-3050	1023	35	with	with	ADP
fnp-3050	1023	36	human	human	ADJ
fnp-3050	1023	37	aging	aging	NOUN
fnp-3050	1023	38	.	.	PUNCT
fnp-3050	1024	1	acta	acta	PROPN
fnp-3050	1024	2	neuropathol	neuropathol	PROPN
fnp-3050	1024	3	128:755	128:755	PROPN
fnp-3050	1024	4	-	-	SYM
fnp-3050	1024	5	766	766	NUM
fnp-3050	1024	6	246	246	NUM
fnp-3050	1024	7	.	.	PUNCT
fnp-3050	1025	1	jellinger	jellinger	PROPN
fnp-3050	1025	2	ka	ka	PROPN
fnp-3050	1025	3	,	,	PUNCT
fnp-3050	1025	4	attems	attem	VERB
fnp-3050	1025	5	j	j	PROPN
fnp-3050	1025	6	(	(	PUNCT
fnp-3050	1025	7	2007	2007	NUM
fnp-3050	1025	8	)	)	PUNCT
fnp-3050	1025	9	neurofibrillary	neurofibrillary	ADJ
fnp-3050	1025	10	tangle	tangle	NOUN
fnp-3050	1025	11	-	-	PUNCT
fnp-3050	1025	12	predominant	predominant	ADJ
fnp-3050	1025	13	dementia	dementia	NOUN
fnp-3050	1025	14	:	:	PUNCT
fnp-3050	1025	15	comparison	comparison	NOUN
fnp-3050	1025	16	with	with	ADP
fnp-3050	1025	17	classical	classical	ADJ
fnp-3050	1025	18	alzheimer	alzheimer	NOUN
fnp-3050	1025	19	disease	disease	NOUN
fnp-3050	1025	20	.	.	PUNCT
fnp-3050	1026	1	acta	acta	PROPN
fnp-3050	1026	2	neuropathol	neuropathol	PROPN
fnp-3050	1026	3	113:107	113:107	NUM
fnp-3050	1026	4	-	-	SYM
fnp-3050	1026	5	117	117	NUM
fnp-3050	1026	6	247	247	NUM
fnp-3050	1026	7	.	.	PUNCT
fnp-3050	1027	1	besser	besser	PROPN
fnp-3050	1027	2	lm	lm	PROPN
fnp-3050	1027	3	,	,	PUNCT
fnp-3050	1027	4	kukull	kukull	PROPN
fnp-3050	1027	5	wa	wa	PROPN
fnp-3050	1027	6	,	,	PUNCT
fnp-3050	1027	7	teylan	teylan	PROPN
fnp-3050	1027	8	ma	ma	PROPN
fnp-3050	1027	9	,	,	PUNCT
fnp-3050	1027	10	bigio	bigio	NOUN
fnp-3050	1027	11	eh	eh	INTJ
fnp-3050	1027	12	,	,	PUNCT
fnp-3050	1027	13	cairns	cairns	PROPN
fnp-3050	1027	14	nj	nj	PROPN
fnp-3050	1027	15	,	,	PUNCT
fnp-3050	1027	16	kofler	kofler	PROPN
fnp-3050	1027	17	jk	jk	PROPN
fnp-3050	1027	18	,	,	PUNCT
fnp-3050	1027	19	montine	montine	PROPN
fnp-3050	1027	20	tj	tj	PROPN
fnp-3050	1027	21	,	,	PUNCT
fnp-3050	1027	22	schneider	schneider	PROPN
fnp-3050	1027	23	ja	ja	PROPN
fnp-3050	1027	24	,	,	PUNCT
fnp-3050	1027	25	nelson	nelson	PROPN
fnp-3050	1027	26	pt	pt	PROPN
fnp-3050	1027	27	(	(	PUNCT
fnp-3050	1027	28	2018	2018	NUM
fnp-3050	1027	29	)	)	PUNCT
fnp-3050	1027	30	the	the	DET
fnp-3050	1027	31	revised	revise	VERB
fnp-3050	1027	32	national	national	PROPN
fnp-3050	1027	33	alzheimer	alzheimer	PROPN
fnp-3050	1027	34	's	's	PART
fnp-3050	1027	35	coordinating	coordinate	VERB
fnp-3050	1027	36	center	center	NOUN
fnp-3050	1027	37	's	's	PART
fnp-3050	1027	38	neuropathology	neuropathology	NOUN
fnp-3050	1027	39	form	form	NOUN
fnp-3050	1027	40	-	-	PUNCT
fnp-3050	1027	41	available	available	ADJ
fnp-3050	1027	42	data	datum	NOUN
fnp-3050	1027	43	and	and	CCONJ
fnp-3050	1027	44	new	new	ADJ
fnp-3050	1027	45	analyses	analysis	NOUN
fnp-3050	1027	46	.	.	PUNCT
fnp-3050	1028	1	j	j	PROPN
fnp-3050	1028	2	neuropathol	neuropathol	PROPN
fnp-3050	1028	3	exp	exp	PROPN
fnp-3050	1028	4	neurol	neurol	PROPN
fnp-3050	1028	5	77:717	77:717	PROPN
fnp-3050	1028	6	-	-	PUNCT
fnp-3050	1028	7	726	726	NUM
fnp-3050	1028	8	248	248	NUM
fnp-3050	1028	9	.	.	PUNCT
fnp-3050	1029	1	jellinger	jellinger	PROPN
fnp-3050	1029	2	ka	ka	PROPN
fnp-3050	1029	3	,	,	PUNCT
fnp-3050	1029	4	attems	attem	VERB
fnp-3050	1029	5	j	j	PROPN
fnp-3050	1029	6	(	(	PUNCT
fnp-3050	1029	7	2015	2015	NUM
fnp-3050	1029	8	)	)	PUNCT
fnp-3050	1029	9	challenges	challenge	NOUN
fnp-3050	1029	10	of	of	ADP
fnp-3050	1029	11	multimorbidity	multimorbidity	NOUN
fnp-3050	1029	12	of	of	ADP
fnp-3050	1029	13	the	the	DET
fnp-3050	1029	14	aging	age	VERB
fnp-3050	1029	15	brain	brain	NOUN
fnp-3050	1029	16	:	:	PUNCT
fnp-3050	1029	17	a	a	DET
fnp-3050	1029	18	critical	critical	ADJ
fnp-3050	1029	19	update	update	NOUN
fnp-3050	1029	20	.	.	PUNCT
fnp-3050	1030	1	j	j	PROPN
fnp-3050	1030	2	neural	neural	ADJ
fnp-3050	1030	3	transm	transm	PROPN
fnp-3050	1030	4	(	(	PUNCT
fnp-3050	1030	5	vienna	vienna	PROPN
fnp-3050	1030	6	)	)	PUNCT
fnp-3050	1030	7	122:505	122:505	PROPN
fnp-3050	1030	8	-	-	SYM
fnp-3050	1030	9	521	521	NUM
fnp-3050	1030	10	249	249	NUM
fnp-3050	1030	11	.	.	PUNCT
fnp-3050	1031	1	josephs	josephs	PROPN
fnp-3050	1031	2	ka	ka	PROPN
fnp-3050	1031	3	,	,	PUNCT
fnp-3050	1031	4	murray	murray	VERB
fnp-3050	1031	5	me	i	PRON
fnp-3050	1031	6	,	,	PUNCT
fnp-3050	1031	7	tosakulwong	tosakulwong	ADP
fnp-3050	1031	8	n	n	CCONJ
fnp-3050	1031	9	,	,	PUNCT
fnp-3050	1031	10	whitwell	whitwell	ADJ
fnp-3050	1031	11	jl	jl	NOUN
fnp-3050	1031	12	,	,	PUNCT
fnp-3050	1031	13	knopman	knopman	NOUN
fnp-3050	1031	14	ds	ds	PROPN
fnp-3050	1031	15	,	,	PUNCT
fnp-3050	1031	16	machulda	machulda	NOUN
fnp-3050	1031	17	mm	mm	PROPN
fnp-3050	1031	18	,	,	PUNCT
fnp-3050	1031	19	weigand	weigand	NOUN
fnp-3050	1031	20	sd	sd	NOUN
fnp-3050	1031	21	,	,	PUNCT
fnp-3050	1031	22	boeve	boeve	NOUN
fnp-3050	1031	23	bf	bf	NOUN
fnp-3050	1031	24	,	,	PUNCT
fnp-3050	1031	25	kantarci	kantarci	PROPN
fnp-3050	1031	26	k	k	PROPN
fnp-3050	1031	27	,	,	PUNCT
fnp-3050	1031	28	petrucelli	petrucelli	PROPN
fnp-3050	1031	29	l	l	PROPN
fnp-3050	1031	30	,	,	PUNCT
fnp-3050	1031	31	lowe	lowe	PROPN
fnp-3050	1031	32	vj	vj	PROPN
fnp-3050	1031	33	,	,	PUNCT
fnp-3050	1031	34	jack	jack	PROPN
fnp-3050	1031	35	cr	cr	PROPN
fnp-3050	1031	36	,	,	PUNCT
fnp-3050	1031	37	jr	jr	PROPN
fnp-3050	1031	38	.	.	PROPN
fnp-3050	1031	39	,	,	PUNCT
fnp-3050	1031	40	petersen	petersen	PROPN
fnp-3050	1031	41	rc	rc	PROPN
fnp-3050	1031	42	,	,	PUNCT
fnp-3050	1031	43	parisi	parisi	PROPN
fnp-3050	1031	44	je	je	PROPN
fnp-3050	1031	45	,	,	PUNCT
fnp-3050	1031	46	dickson	dickson	PROPN
fnp-3050	1031	47	dw	dw	PROPN
fnp-3050	1031	48	(	(	PUNCT
fnp-3050	1031	49	2017	2017	NUM
fnp-3050	1031	50	)	)	PUNCT
fnp-3050	1031	51	tau	tau	PROPN
fnp-3050	1031	52	aggregation	aggregation	NOUN
fnp-3050	1031	53	influences	influence	VERB
fnp-3050	1031	54	cognition	cognition	NOUN
fnp-3050	1031	55	and	and	CCONJ
fnp-3050	1031	56	hippocampal	hippocampal	ADJ
fnp-3050	1031	57	atrophy	atrophy	NOUN
fnp-3050	1031	58	in	in	ADP
fnp-3050	1031	59	the	the	DET
fnp-3050	1031	60	absence	absence	NOUN
fnp-3050	1031	61	of	of	ADP
fnp-3050	1031	62	beta	beta	NOUN
fnp-3050	1031	63	-	-	PUNCT
fnp-3050	1031	64	amyloid	amyloid	NOUN
fnp-3050	1031	65	:	:	PUNCT
fnp-3050	1031	66	a	a	DET
fnp-3050	1031	67	clinico	clinico	NOUN
fnp-3050	1031	68	-	-	PUNCT
fnp-3050	1031	69	imaging	imaging	ADJ
fnp-3050	1031	70	-	-	PUNCT
fnp-3050	1031	71	pathological	pathological	ADJ
fnp-3050	1031	72	study	study	NOUN
fnp-3050	1031	73	of	of	ADP
fnp-3050	1031	74	primary	primary	ADJ
fnp-3050	1031	75	age	age	NOUN
fnp-3050	1031	76	-	-	PUNCT
fnp-3050	1031	77	related	relate	VERB
fnp-3050	1031	78	tauopathy	tauopathy	NOUN
fnp-3050	1031	79	(	(	PUNCT
fnp-3050	1031	80	part	part	NOUN
fnp-3050	1031	81	)	)	PUNCT
fnp-3050	1031	82	.	.	PUNCT
fnp-3050	1032	1	acta	acta	PROPN
fnp-3050	1032	2	neuropathol	neuropathol	PROPN
fnp-3050	1032	3	133:705	133:705	NUM
fnp-3050	1032	4	-	-	SYM
fnp-3050	1032	5	715	715	NUM
fnp-3050	1032	6	250	250	NUM
fnp-3050	1032	7	.	.	PUNCT
fnp-3050	1033	1	jellinger	jellinger	PROPN
fnp-3050	1033	2	ka	ka	PROPN
fnp-3050	1034	1	(	(	PUNCT
fnp-3050	1034	2	2018	2018	NUM
fnp-3050	1034	3	)	)	PUNCT
fnp-3050	1034	4	different	different	ADJ
fnp-3050	1034	5	patterns	pattern	NOUN
fnp-3050	1034	6	of	of	ADP
fnp-3050	1034	7	hippocampal	hippocampal	ADJ
fnp-3050	1034	8	tau	tau	PROPN
fnp-3050	1034	9	pathology	pathology	PROPN
fnp-3050	1034	10	in	in	ADP
fnp-3050	1034	11	alzheimer	alzheimer	PROPN
fnp-3050	1034	12	's	's	PART
fnp-3050	1034	13	disease	disease	NOUN
fnp-3050	1034	14	and	and	CCONJ
fnp-3050	1034	15	part	part	NOUN
fnp-3050	1034	16	.	.	PUNCT
fnp-3050	1035	1	acta	acta	PROPN
fnp-3050	1035	2	neuropathol	neuropathol	PROPN
fnp-3050	1035	3	136:811	136:811	PROPN
fnp-3050	1035	4	-	-	PUNCT
fnp-3050	1035	5	813	813	NUM
fnp-3050	1035	6	251	251	NUM
fnp-3050	1035	7	.	.	PUNCT
fnp-3050	1036	1	zhang	zhang	PROPN
fnp-3050	1036	2	l	l	PROPN
fnp-3050	1036	3	,	,	PUNCT
fnp-3050	1036	4	jiang	jiang	PROPN
fnp-3050	1036	5	y	y	PROPN
fnp-3050	1036	6	,	,	PUNCT
fnp-3050	1036	7	zhu	zhu	PROPN
fnp-3050	1036	8	j	j	PROPN
fnp-3050	1036	9	,	,	PUNCT
fnp-3050	1036	10	liang	liang	PROPN
fnp-3050	1036	11	h	h	PROPN
fnp-3050	1036	12	,	,	PUNCT
fnp-3050	1036	13	he	he	PRON
fnp-3050	1036	14	x	x	PROPN
fnp-3050	1036	15	,	,	PUNCT
fnp-3050	1036	16	qian	qian	PROPN
fnp-3050	1036	17	j	j	PROPN
fnp-3050	1036	18	,	,	PUNCT
fnp-3050	1036	19	lin	lin	PROPN
fnp-3050	1036	20	h	h	PROPN
fnp-3050	1036	21	,	,	PUNCT
fnp-3050	1036	22	tao	tao	PROPN
fnp-3050	1036	23	y	y	PROPN
fnp-3050	1036	24	,	,	PUNCT
fnp-3050	1036	25	zhu	zhu	PROPN
fnp-3050	1036	26	k	k	X
fnp-3050	1036	27	(	(	PUNCT
fnp-3050	1036	28	2020	2020	NUM
fnp-3050	1036	29	)	)	PUNCT
fnp-3050	1036	30	quantitative	quantitative	ADJ
fnp-3050	1036	31	assessment	assessment	NOUN
fnp-3050	1036	32	of	of	ADP
fnp-3050	1036	33	hippocampal	hippocampal	ADJ
fnp-3050	1036	34	tau	tau	PROPN
fnp-3050	1036	35	pathology	pathology	NOUN
fnp-3050	1036	36	in	in	ADP
fnp-3050	1036	37	ad	ad	NOUN
fnp-3050	1036	38	and	and	CCONJ
fnp-3050	1036	39	part	part	NOUN
fnp-3050	1036	40	.	.	PUNCT
fnp-3050	1037	1	j	j	PROPN
fnp-3050	1037	2	mol	mol	ADP
fnp-3050	1037	3	neurosci	neurosci	PROPN
fnp-3050	1037	4	70:1808	70:1808	NOUN
fnp-3050	1037	5	-	-	SYM
fnp-3050	1037	6	1811	1811	NUM
fnp-3050	1037	7	252	252	NUM
fnp-3050	1037	8	.	.	PUNCT
fnp-3050	1038	1	zhang	zhang	PROPN
fnp-3050	1038	2	x	x	PROPN
fnp-3050	1038	3	,	,	PUNCT
fnp-3050	1038	4	sun	sun	PROPN
fnp-3050	1038	5	b	b	PROPN
fnp-3050	1038	6	,	,	PUNCT
fnp-3050	1038	7	wang	wang	PROPN
fnp-3050	1038	8	x	x	PROPN
fnp-3050	1038	9	,	,	PUNCT
fnp-3050	1038	10	lu	lu	PROPN
fnp-3050	1038	11	h	h	NOUN
fnp-3050	1038	12	,	,	PUNCT
fnp-3050	1038	13	shao	shao	PROPN
fnp-3050	1038	14	f	f	PROPN
fnp-3050	1038	15	,	,	PUNCT
fnp-3050	1038	16	rozemuller	rozemuller	NOUN
fnp-3050	1038	17	ajm	ajm	PROPN
fnp-3050	1038	18	,	,	PUNCT
fnp-3050	1038	19	liang	liang	PROPN
fnp-3050	1038	20	h	h	PROPN
fnp-3050	1038	21	,	,	PUNCT
fnp-3050	1038	22	liu	liu	PROPN
fnp-3050	1038	23	c	c	PROPN
fnp-3050	1038	24	,	,	PUNCT
fnp-3050	1038	25	chen	chen	PROPN
fnp-3050	1038	26	j	j	PROPN
fnp-3050	1038	27	,	,	PUNCT
fnp-3050	1038	28	huang	huang	PROPN
fnp-3050	1038	29	m	m	PROPN
fnp-3050	1038	30	,	,	PUNCT
fnp-3050	1038	31	zhu	zhu	PROPN
fnp-3050	1038	32	k	k	PROPN
fnp-3050	1038	33	(	(	PUNCT
fnp-3050	1038	34	2019	2019	NUM
fnp-3050	1038	35	)	)	PUNCT
fnp-3050	1038	36	phosphorylated	phosphorylate	VERB
fnp-3050	1038	37	tdp-43	tdp-43	NOUN
fnp-3050	1038	38	staging	staging	NOUN
fnp-3050	1038	39	of	of	ADP
fnp-3050	1038	40	primary	primary	ADJ
fnp-3050	1038	41	age	age	NOUN
fnp-3050	1038	42	-	-	PUNCT
fnp-3050	1038	43	related	relate	VERB
fnp-3050	1038	44	tauopathy	tauopathy	NOUN
fnp-3050	1038	45	.	.	PUNCT
fnp-3050	1039	1	neurosci	neurosci	PROPN
fnp-3050	1039	2	bull	bull	PROPN
fnp-3050	1039	3	35:183	35:183	NUM
fnp-3050	1039	4	-	-	SYM
fnp-3050	1039	5	192	192	NUM
fnp-3050	1039	6	253	253	NUM
fnp-3050	1039	7	.	.	PUNCT
fnp-3050	1040	1	jellinger	jellinger	PROPN
fnp-3050	1040	2	ka	ka	PROPN
fnp-3050	1040	3	,	,	PUNCT
fnp-3050	1040	4	alafuzoff	alafuzoff	NOUN
fnp-3050	1040	5	i	i	PRON
fnp-3050	1040	6	,	,	PUNCT
fnp-3050	1040	7	attems	attem	VERB
fnp-3050	1040	8	j	j	PROPN
fnp-3050	1040	9	,	,	PUNCT
fnp-3050	1040	10	beach	beach	PROPN
fnp-3050	1040	11	tg	tg	PROPN
fnp-3050	1040	12	,	,	PUNCT
fnp-3050	1040	13	cairns	cairns	PROPN
fnp-3050	1040	14	nj	nj	PROPN
fnp-3050	1040	15	,	,	PUNCT
fnp-3050	1040	16	crary	crary	PROPN
fnp-3050	1040	17	jf	jf	PROPN
fnp-3050	1040	18	,	,	PUNCT
fnp-3050	1040	19	dickson	dickson	PROPN
fnp-3050	1040	20	dw	dw	PROPN
fnp-3050	1040	21	,	,	PUNCT
fnp-3050	1040	22	hof	hof	PROPN
fnp-3050	1040	23	pr	pr	PROPN
fnp-3050	1040	24	,	,	PUNCT
fnp-3050	1040	25	hyman	hyman	PROPN
fnp-3050	1040	26	bt	bt	PROPN
fnp-3050	1040	27	,	,	PUNCT
fnp-3050	1040	28	jack	jack	PROPN
fnp-3050	1040	29	cr	cr	PROPN
fnp-3050	1040	30	,	,	PUNCT
fnp-3050	1040	31	jr	jr	PROPN
fnp-3050	1040	32	.	.	PROPN
fnp-3050	1040	33	,	,	PUNCT
fnp-3050	1040	34	jicha	jicha	PROPN
fnp-3050	1040	35	ga	ga	PROPN
fnp-3050	1040	36	,	,	PUNCT
fnp-3050	1040	37	knopman	knopman	NOUN
fnp-3050	1040	38	ds	ds	PROPN
fnp-3050	1040	39	,	,	PUNCT
fnp-3050	1040	40	kovacs	kovacs	PROPN
fnp-3050	1040	41	gg	gg	PROPN
fnp-3050	1040	42	,	,	PUNCT
fnp-3050	1040	43	mackenzie	mackenzie	PROPN
fnp-3050	1040	44	ir	ir	PROPN
fnp-3050	1040	45	,	,	PUNCT
fnp-3050	1040	46	masliah	masliah	PROPN
fnp-3050	1040	47	e	e	PROPN
fnp-3050	1040	48	,	,	PUNCT
fnp-3050	1040	49	montine	montine	PROPN
fnp-3050	1040	50	tj	tj	PROPN
fnp-3050	1040	51	,	,	PUNCT
fnp-3050	1040	52	nelson	nelson	PROPN
fnp-3050	1040	53	pt	pt	PROPN
fnp-3050	1040	54	,	,	PUNCT
fnp-3050	1040	55	schmitt	schmitt	PROPN
fnp-3050	1040	56	f	f	PROPN
fnp-3050	1040	57	,	,	PUNCT
fnp-3050	1040	58	schneider	schneider	PROPN
fnp-3050	1040	59	ja	ja	PROPN
fnp-3050	1040	60	,	,	PUNCT
fnp-3050	1040	61	serrano	serrano	PROPN
fnp-3050	1040	62	-	-	PUNCT
fnp-3050	1040	63	pozo	pozo	PROPN
fnp-3050	1040	64	a	a	PRON
fnp-3050	1040	65	,	,	PUNCT
fnp-3050	1040	66	thal	thal	PROPN
fnp-3050	1040	67	dr	dr	PROPN
fnp-3050	1040	68	,	,	PUNCT
fnp-3050	1040	69	toledo	toledo	PROPN
fnp-3050	1040	70	jb	jb	PROPN
fnp-3050	1040	71	,	,	PUNCT
fnp-3050	1040	72	trojanowski	trojanowski	PROPN
fnp-3050	1040	73	jq	jq	PROPN
fnp-3050	1040	74	,	,	PUNCT
fnp-3050	1040	75	troncoso	troncoso	PROPN
fnp-3050	1040	76	jc	jc	PROPN
fnp-3050	1040	77	,	,	PUNCT
fnp-3050	1040	78	vonsattel	vonsattel	PROPN
fnp-3050	1040	79	jp	jp	PROPN
fnp-3050	1040	80	,	,	PUNCT
fnp-3050	1040	81	wisniewski	wisniewski	PROPN
fnp-3050	1040	82	t	t	PROPN
fnp-3050	1040	83	(	(	PUNCT
fnp-3050	1040	84	2015	2015	NUM
fnp-3050	1040	85	)	)	PUNCT
fnp-3050	1040	86	part	part	NOUN
fnp-3050	1040	87	,	,	PUNCT
fnp-3050	1040	88	a	a	DET
fnp-3050	1040	89	distinct	distinct	ADJ
fnp-3050	1040	90	tauopathy	tauopathy	NOUN
fnp-3050	1040	91	,	,	PUNCT
fnp-3050	1040	92	different	different	ADJ
fnp-3050	1040	93	from	from	ADP
fnp-3050	1040	94	classical	classical	ADJ
fnp-3050	1040	95	sporadic	sporadic	ADJ
fnp-3050	1040	96	alzheimer	alzheimer	PROPN
fnp-3050	1040	97	disease	disease	NOUN
fnp-3050	1040	98	.	.	PUNCT
fnp-3050	1041	1	acta	acta	PROPN
fnp-3050	1041	2	neuropathol	neuropathol	PROPN
fnp-3050	1041	3	129:757	129:757	PROPN
fnp-3050	1041	4	-	-	SYM
fnp-3050	1041	5	762	762	NUM
fnp-3050	1041	6	254	254	NUM
fnp-3050	1041	7	.	.	PUNCT
fnp-3050	1042	1	jellinger	jellinger	PROPN
fnp-3050	1042	2	ka	ka	PROPN
fnp-3050	1042	3	(	(	PUNCT
fnp-3050	1042	4	2016	2016	NUM
fnp-3050	1042	5	)	)	PUNCT
fnp-3050	1042	6	commentary	commentary	NOUN
fnp-3050	1042	7	on	on	ADP
fnp-3050	1042	8	the	the	DET
fnp-3050	1042	9	paper	paper	NOUN
fnp-3050	1042	10	"	"	PUNCT
fnp-3050	1042	11	part	part	NOUN
fnp-3050	1042	12	,	,	PUNCT
fnp-3050	1042	13	a	a	DET
fnp-3050	1042	14	distinct	distinct	ADJ
fnp-3050	1042	15	tauopathy	tauopathy	NOUN
fnp-3050	1042	16	,	,	PUNCT
fnp-3050	1042	17	different	different	ADJ
fnp-3050	1042	18	from	from	ADP
fnp-3050	1042	19	classical	classical	ADJ
fnp-3050	1042	20	1	1	NUM
fnp-3050	1042	21	.	.	PUNCT
fnp-3050	1042	22	sporadic	sporadic	ADJ
fnp-3050	1042	23	alzheimer	alzheimer	PROPN
fnp-3050	1042	24	disease	disease	PROPN
fnp-3050	1042	25	"	"	PUNCT
fnp-3050	1042	26	.	.	PUNCT
fnp-3050	1043	1	j	j	PROPN
fnp-3050	1043	2	clin	clin	PROPN
fnp-3050	1043	3	cell	cell	PROPN
fnp-3050	1043	4	immunol	immunol	NOUN
fnp-3050	1043	5	7:1000480	7:1000480	NUM
fnp-3050	1043	6	255	255	NUM
fnp-3050	1043	7	.	.	PUNCT
fnp-3050	1044	1	bancher	bancher	PROPN
fnp-3050	1044	2	c	c	NOUN
fnp-3050	1044	3	,	,	PUNCT
fnp-3050	1044	4	egensperger	egensperger	ADV
fnp-3050	1044	5	r	r	NOUN
fnp-3050	1044	6	,	,	PUNCT
fnp-3050	1044	7	kosel	kosel	PROPN
fnp-3050	1044	8	s	s	PROPN
fnp-3050	1044	9	,	,	PUNCT
fnp-3050	1044	10	jellinger	jellinger	PROPN
fnp-3050	1044	11	k	k	PROPN
fnp-3050	1044	12	,	,	PUNCT
fnp-3050	1044	13	graeber	graeber	NOUN
fnp-3050	1044	14	mb	mb	PROPN
fnp-3050	1044	15	(	(	PUNCT
fnp-3050	1044	16	1997	1997	NUM
fnp-3050	1044	17	)	)	PUNCT
fnp-3050	1044	18	low	low	ADJ
fnp-3050	1044	19	prevalence	prevalence	NOUN
fnp-3050	1044	20	of	of	ADP
fnp-3050	1044	21	apolipoprotein	apolipoprotein	ADJ
fnp-3050	1044	22	e	e	PROPN
fnp-3050	1044	23	epsilon	epsilon	PROPN
fnp-3050	1044	24	4	4	NUM
fnp-3050	1044	25	allele	allele	NOUN
fnp-3050	1044	26	in	in	ADP
fnp-3050	1044	27	the	the	DET
fnp-3050	1044	28	neurofibrillary	neurofibrillary	ADJ
fnp-3050	1044	29	tangle	tangle	NOUN
fnp-3050	1044	30	predominant	predominant	ADJ
fnp-3050	1044	31	form	form	NOUN
fnp-3050	1044	32	of	of	ADP
fnp-3050	1044	33	senile	senile	ADJ
fnp-3050	1044	34	dementia	dementia	NOUN
fnp-3050	1044	35	.	.	PUNCT
fnp-3050	1045	1	acta	acta	PROPN
fnp-3050	1045	2	neuropathol	neuropathol	PROPN
fnp-3050	1045	3	94:403	94:403	NUM
fnp-3050	1045	4	-	-	PUNCT
fnp-3050	1045	5	409	409	NUM
fnp-3050	1045	6	256	256	NUM
fnp-3050	1045	7	.	.	PUNCT
fnp-3050	1046	1	mcmillan	mcmillan	PROPN
fnp-3050	1046	2	ct	ct	PROPN
fnp-3050	1046	3	,	,	PUNCT
fnp-3050	1046	4	lee	lee	PROPN
fnp-3050	1046	5	eb	eb	PROPN
fnp-3050	1046	6	,	,	PUNCT
fnp-3050	1046	7	jefferson	jefferson	PROPN
fnp-3050	1046	8	-	-	PUNCT
fnp-3050	1046	9	george	george	PROPN
fnp-3050	1046	10	k	k	PROPN
fnp-3050	1046	11	,	,	PUNCT
fnp-3050	1046	12	naj	naj	PROPN
fnp-3050	1046	13	a	a	PROPN
fnp-3050	1046	14	,	,	PUNCT
fnp-3050	1046	15	van	van	PROPN
fnp-3050	1046	16	deerlin	deerlin	PROPN
fnp-3050	1046	17	vm	vm	PROPN
fnp-3050	1046	18	,	,	PUNCT
fnp-3050	1046	19	trojanowski	trojanowski	PROPN
fnp-3050	1046	20	jq	jq	PROPN
fnp-3050	1046	21	,	,	PUNCT
fnp-3050	1046	22	wolk	wolk	NOUN
fnp-3050	1046	23	da	da	PROPN
fnp-3050	1046	24	(	(	PUNCT
fnp-3050	1046	25	2018	2018	NUM
fnp-3050	1046	26	)	)	PUNCT
fnp-3050	1046	27	alzheimer	alzheimer	PROPN
fnp-3050	1046	28	's	's	PART
fnp-3050	1046	29	genetic	genetic	ADJ
fnp-3050	1046	30	risk	risk	NOUN
fnp-3050	1046	31	is	be	AUX
fnp-3050	1046	32	reduced	reduce	VERB
fnp-3050	1046	33	in	in	ADP
fnp-3050	1046	34	primary	primary	ADJ
fnp-3050	1046	35	age	age	NOUN
fnp-3050	1046	36	-	-	PUNCT
fnp-3050	1046	37	related	relate	VERB
fnp-3050	1046	38	tauopathy	tauopathy	NOUN
fnp-3050	1046	39	:	:	PUNCT
fnp-3050	1046	40	a	a	DET
fnp-3050	1046	41	potential	potential	ADJ
fnp-3050	1046	42	model	model	NOUN
fnp-3050	1046	43	of	of	ADP
fnp-3050	1046	44	resistance	resistance	NOUN
fnp-3050	1046	45	?	?	PUNCT
fnp-3050	1047	1	ann	ann	PROPN
fnp-3050	1047	2	clin	clin	PROPN
fnp-3050	1047	3	transl	transl	PROPN
fnp-3050	1047	4	neurol	neurol	PROPN
fnp-3050	1047	5	5:927	5:927	PROPN
fnp-3050	1047	6	-	-	SYM
fnp-3050	1047	7	934	934	NUM
fnp-3050	1047	8	257	257	NUM
fnp-3050	1047	9	.	.	PUNCT
fnp-3050	1048	1	hickman	hickman	PROPN
fnp-3050	1048	2	ra	ra	PROPN
fnp-3050	1048	3	,	,	PUNCT
fnp-3050	1048	4	flowers	flowers	PROPN
fnp-3050	1048	5	xe	xe	PROPN
fnp-3050	1048	6	,	,	PUNCT
fnp-3050	1048	7	wisniewski	wisniewski	PROPN
fnp-3050	1048	8	t	t	PROPN
fnp-3050	1048	9	(	(	PUNCT
fnp-3050	1048	10	2020	2020	NUM
fnp-3050	1048	11	)	)	PUNCT
fnp-3050	1048	12	primary	primary	ADJ
fnp-3050	1048	13	age	age	NOUN
fnp-3050	1048	14	-	-	PUNCT
fnp-3050	1048	15	related	relate	VERB
fnp-3050	1048	16	tauopathy	tauopathy	NOUN
fnp-3050	1048	17	(	(	PUNCT
fnp-3050	1048	18	part	part	NOUN
fnp-3050	1048	19	):	):	PUNCT
fnp-3050	1048	20	addressing	address	VERB
fnp-3050	1048	21	the	the	DET
fnp-3050	1048	22	spectrum	spectrum	NOUN
fnp-3050	1048	23	of	of	ADP
fnp-3050	1048	24	neuronal	neuronal	ADJ
fnp-3050	1048	25	tauopathic	tauopathic	ADJ
fnp-3050	1048	26	changes	change	NOUN
fnp-3050	1048	27	in	in	ADP
fnp-3050	1048	28	the	the	DET
fnp-3050	1048	29	aging	age	VERB
fnp-3050	1048	30	brain	brain	NOUN
fnp-3050	1048	31	.	.	PUNCT
fnp-3050	1049	1	curr	curr	PROPN
fnp-3050	1049	2	neurol	neurol	PROPN
fnp-3050	1049	3	neurosci	neurosci	PROPN
fnp-3050	1049	4	rep	rep	PROPN
fnp-3050	1049	5	20:39	20:39	NUM
fnp-3050	1049	6	258	258	NUM
fnp-3050	1049	7	.	.	PUNCT
fnp-3050	1050	1	besser	besser	PROPN
fnp-3050	1050	2	lm	lm	PROPN
fnp-3050	1050	3	,	,	PUNCT
fnp-3050	1050	4	teylan	teylan	NOUN
fnp-3050	1050	5	ma	ma	PROPN
fnp-3050	1050	6	,	,	PUNCT
fnp-3050	1050	7	nelson	nelson	PROPN
fnp-3050	1050	8	pt	pt	PROPN
fnp-3050	1050	9	(	(	PUNCT
fnp-3050	1050	10	2020	2020	NUM
fnp-3050	1050	11	)	)	PUNCT
fnp-3050	1050	12	limbic	limbic	ADJ
fnp-3050	1050	13	predominant	predominant	ADJ
fnp-3050	1050	14	age	age	NOUN
fnp-3050	1050	15	-	-	PUNCT
fnp-3050	1050	16	related	relate	VERB
fnp-3050	1050	17	tdp-43	tdp-43	NOUN
fnp-3050	1050	18	encephalopathy	encephalopathy	ADJ
fnp-3050	1050	19	(	(	PUNCT
fnp-3050	1050	20	late	late	ADJ
fnp-3050	1050	21	):	):	PUNCT
fnp-3050	1050	22	clinical	clinical	ADJ
fnp-3050	1050	23	and	and	CCONJ
fnp-3050	1050	24	neuropathological	neuropathological	ADJ
fnp-3050	1050	25	associations	association	NOUN
fnp-3050	1050	26	.	.	PUNCT
fnp-3050	1051	1	j	j	PROPN
fnp-3050	1051	2	neuropathol	neuropathol	PROPN
fnp-3050	1051	3	exp	exp	PROPN
fnp-3050	1051	4	neurol	neurol	PROPN
fnp-3050	1051	5	79:305	79:305	PROPN
fnp-3050	1051	6	-	-	SYM
fnp-3050	1051	7	313	313	NUM
fnp-3050	1051	8	259	259	NUM
fnp-3050	1051	9	.	.	PUNCT
fnp-3050	1052	1	nelson	nelson	PROPN
fnp-3050	1052	2	pt	pt	PROPN
fnp-3050	1052	3	,	,	PUNCT
fnp-3050	1052	4	dickson	dickson	PROPN
fnp-3050	1052	5	dw	dw	PROPN
fnp-3050	1052	6	,	,	PUNCT
fnp-3050	1052	7	trojanowski	trojanowski	PROPN
fnp-3050	1052	8	jq	jq	PROPN
fnp-3050	1052	9	,	,	PUNCT
fnp-3050	1052	10	jack	jack	PROPN
fnp-3050	1052	11	cr	cr	PROPN
fnp-3050	1052	12	,	,	PUNCT
fnp-3050	1052	13	boyle	boyle	PROPN
fnp-3050	1052	14	pa	pa	PROPN
fnp-3050	1052	15	,	,	PUNCT
fnp-3050	1052	16	arfanakis	arfanakis	PROPN
fnp-3050	1052	17	k	k	NOUN
fnp-3050	1052	18	,	,	PUNCT
fnp-3050	1052	19	rademakers	rademaker	NOUN
fnp-3050	1052	20	r	r	NOUN
fnp-3050	1052	21	,	,	PUNCT
fnp-3050	1052	22	alafuzoff	alafuzoff	NOUN
fnp-3050	1053	1	i	i	PRON
fnp-3050	1053	2	,	,	PUNCT
fnp-3050	1053	3	attems	attem	VERB
fnp-3050	1053	4	j	j	PROPN
fnp-3050	1053	5	,	,	PUNCT
fnp-3050	1053	6	brayne	brayne	PROPN
fnp-3050	1053	7	c	c	PROPN
fnp-3050	1053	8	,	,	PUNCT
fnp-3050	1053	9	coyle	coyle	NOUN
fnp-3050	1053	10	-	-	PUNCT
fnp-3050	1053	11	gilchrist	gilchrist	NOUN
fnp-3050	1053	12	its	its	PRON
fnp-3050	1053	13	,	,	PUNCT
fnp-3050	1053	14	chui	chui	PROPN
fnp-3050	1053	15	hc	hc	PROPN
fnp-3050	1053	16	,	,	PUNCT
fnp-3050	1053	17	fardo	fardo	PROPN
fnp-3050	1053	18	dw	dw	PROPN
fnp-3050	1053	19	,	,	PUNCT
fnp-3050	1053	20	flanagan	flanagan	VERB
fnp-3050	1053	21	me	i	PRON
fnp-3050	1053	22	,	,	PUNCT
fnp-3050	1053	23	halliday	halliday	PROPN
fnp-3050	1053	24	g	g	PROPN
fnp-3050	1053	25	,	,	PUNCT
fnp-3050	1053	26	hokkanen	hokkanen	ADJ
fnp-3050	1053	27	srk	srk	NOUN
fnp-3050	1053	28	,	,	PUNCT
fnp-3050	1053	29	hunter	hunter	NOUN
fnp-3050	1053	30	s	s	PROPN
fnp-3050	1053	31	,	,	PUNCT
fnp-3050	1053	32	jicha	jicha	PROPN
fnp-3050	1053	33	ga	ga	PROPN
fnp-3050	1053	34	,	,	PUNCT
fnp-3050	1053	35	katsumata	katsumata	PROPN
fnp-3050	1053	36	y	y	PROPN
fnp-3050	1053	37	,	,	PUNCT
fnp-3050	1053	38	kawas	kawa	VERB
fnp-3050	1053	39	ch	ch	PROPN
fnp-3050	1053	40	,	,	PUNCT
fnp-3050	1053	41	keene	keene	PROPN
fnp-3050	1053	42	cd	cd	PROPN
fnp-3050	1053	43	,	,	PUNCT
fnp-3050	1053	44	kovacs	kovacs	PROPN
fnp-3050	1053	45	gg	gg	PROPN
fnp-3050	1053	46	,	,	PUNCT
fnp-3050	1053	47	kukull	kukull	PROPN
fnp-3050	1053	48	wa	wa	PROPN
fnp-3050	1053	49	,	,	PUNCT
fnp-3050	1053	50	levey	levey	PROPN
fnp-3050	1053	51	ai	ai	PROPN
fnp-3050	1053	52	,	,	PUNCT
fnp-3050	1053	53	makkinejad	makkinejad	ADJ
fnp-3050	1053	54	n	n	NOUN
fnp-3050	1053	55	,	,	PUNCT
fnp-3050	1053	56	montine	montine	PROPN
fnp-3050	1053	57	tj	tj	NOUN
fnp-3050	1053	58	,	,	PUNCT
fnp-3050	1053	59	murayama	murayama	PROPN
fnp-3050	1053	60	s	s	PART
fnp-3050	1053	61	,	,	PUNCT
fnp-3050	1053	62	murray	murray	VERB
fnp-3050	1053	63	me	i	PRON
fnp-3050	1053	64	,	,	PUNCT
fnp-3050	1053	65	nag	nag	VERB
fnp-3050	1053	66	s	s	SYM
fnp-3050	1053	67	,	,	PUNCT
fnp-3050	1053	68	rissman	rissman	PROPN
fnp-3050	1053	69	ra	ra	PROPN
fnp-3050	1053	70	,	,	PUNCT
fnp-3050	1053	71	seeley	seeley	PROPN
fnp-3050	1053	72	ww	ww	PROPN
fnp-3050	1053	73	,	,	PUNCT
fnp-3050	1053	74	sperling	sperling	PROPN
fnp-3050	1053	75	ra	ra	PROPN
fnp-3050	1053	76	,	,	PUNCT
fnp-3050	1054	1	white	white	PROPN
fnp-3050	1054	2	iii	iii	PROPN
fnp-3050	1054	3	cl	cl	PROPN
fnp-3050	1054	4	,	,	PUNCT
fnp-3050	1054	5	yu	yu	PROPN
fnp-3050	1054	6	l	l	PROPN
fnp-3050	1054	7	,	,	PUNCT
fnp-3050	1054	8	schneider	schneider	PROPN
fnp-3050	1054	9	ja	ja	PROPN
fnp-3050	1054	10	(	(	PUNCT
fnp-3050	1054	11	2019	2019	NUM
fnp-3050	1054	12	)	)	PUNCT
fnp-3050	1054	13	limbic	limbic	NOUN
fnp-3050	1054	14	-	-	PUNCT
fnp-3050	1054	15	predominant	predominant	ADJ
fnp-3050	1054	16	age	age	NOUN
fnp-3050	1054	17	-	-	PUNCT
fnp-3050	1054	18	related	relate	VERB
fnp-3050	1054	19	tdp-43	tdp-43	NOUN
fnp-3050	1054	20	encephalopathy	encephalopathy	ADJ
fnp-3050	1054	21	(	(	PUNCT
fnp-3050	1054	22	late	late	ADV
fnp-3050	1054	23	):	):	PUNCT
fnp-3050	1054	24	consensus	consensus	NOUN
fnp-3050	1054	25	working	work	VERB
fnp-3050	1054	26	group	group	NOUN
fnp-3050	1054	27	report	report	NOUN
fnp-3050	1054	28	.	.	PUNCT
fnp-3050	1055	1	brain	brain	NOUN
fnp-3050	1055	2	142:1503	142:1503	NUM
fnp-3050	1055	3	-	-	PUNCT
fnp-3050	1055	4	1527	1527	NUM
fnp-3050	1055	5	260	260	NUM
fnp-3050	1055	6	.	.	PUNCT
fnp-3050	1056	1	robinson	robinson	PROPN
fnp-3050	1056	2	jl	jl	PROPN
fnp-3050	1056	3	,	,	PUNCT
fnp-3050	1056	4	porta	porta	PROPN
fnp-3050	1056	5	s	s	PROPN
fnp-3050	1056	6	,	,	PUNCT
fnp-3050	1056	7	garrett	garrett	PROPN
fnp-3050	1056	8	fg	fg	PROPN
fnp-3050	1056	9	,	,	PUNCT
fnp-3050	1056	10	zhang	zhang	PROPN
fnp-3050	1056	11	p	p	PROPN
fnp-3050	1056	12	,	,	PUNCT
fnp-3050	1056	13	xie	xie	PROPN
fnp-3050	1056	14	sx	sx	PROPN
fnp-3050	1056	15	,	,	PUNCT
fnp-3050	1056	16	suh	suh	PROPN
fnp-3050	1056	17	e	e	PROPN
fnp-3050	1056	18	,	,	PUNCT
fnp-3050	1056	19	van	van	PROPN
fnp-3050	1056	20	deerlin	deerlin	PROPN
fnp-3050	1056	21	vm	vm	PROPN
fnp-3050	1056	22	,	,	PUNCT
fnp-3050	1056	23	abner	abner	PROPN
fnp-3050	1056	24	el	el	PROPN
fnp-3050	1056	25	,	,	PUNCT
fnp-3050	1056	26	jicha	jicha	PROPN
fnp-3050	1056	27	ga	ga	PROPN
fnp-3050	1056	28	,	,	PUNCT
fnp-3050	1056	29	barber	barber	PROPN
fnp-3050	1056	30	jm	jm	PROPN
fnp-3050	1056	31	,	,	PUNCT
fnp-3050	1056	32	lee	lee	PROPN
fnp-3050	1056	33	vm	vm	PROPN
fnp-3050	1056	34	,	,	PUNCT
fnp-3050	1056	35	lee	lee	PROPN
fnp-3050	1056	36	eb	eb	PROPN
fnp-3050	1056	37	,	,	PUNCT
fnp-3050	1056	38	trojanowski	trojanowski	PROPN
fnp-3050	1056	39	jq	jq	PROPN
fnp-3050	1056	40	,	,	PUNCT
fnp-3050	1056	41	nelson	nelson	PROPN
fnp-3050	1056	42	pt	pt	PROPN
fnp-3050	1056	43	(	(	PUNCT
fnp-3050	1056	44	2020	2020	NUM
fnp-3050	1056	45	)	)	PUNCT
fnp-3050	1056	46	limbic	limbic	NOUN
fnp-3050	1056	47	-	-	PUNCT
fnp-3050	1056	48	predominant	predominant	ADJ
fnp-3050	1056	49	age	age	NOUN
fnp-3050	1056	50	-	-	PUNCT
fnp-3050	1056	51	related	relate	VERB
fnp-3050	1056	52	tdp-43	tdp-43	NOUN
fnp-3050	1056	53	encephalopathy	encephalopathy	NOUN
fnp-3050	1056	54	differs	differ	VERB
fnp-3050	1056	55	from	from	ADP
fnp-3050	1056	56	frontotemporal	frontotemporal	ADJ
fnp-3050	1056	57	lobar	lobar	ADJ
fnp-3050	1056	58	degeneration	degeneration	NOUN
fnp-3050	1056	59	.	.	PUNCT
fnp-3050	1057	1	brain	brain	NOUN
fnp-3050	1057	2	143:2844	143:2844	NUM
fnp-3050	1057	3	-	-	SYM
fnp-3050	1057	4	2857	2857	NUM
fnp-3050	1057	5	261	261	NUM
fnp-3050	1057	6	.	.	PUNCT
fnp-3050	1058	1	teylan	teylan	PROPN
fnp-3050	1058	2	m	m	PROPN
fnp-3050	1058	3	,	,	PUNCT
fnp-3050	1058	4	besser	besser	NOUN
fnp-3050	1058	5	lm	lm	PROPN
fnp-3050	1058	6	,	,	PUNCT
fnp-3050	1058	7	crary	crary	PROPN
fnp-3050	1058	8	jf	jf	PROPN
fnp-3050	1058	9	,	,	PUNCT
fnp-3050	1058	10	mock	mock	ADJ
fnp-3050	1058	11	c	c	NOUN
fnp-3050	1058	12	,	,	PUNCT
fnp-3050	1058	13	gauthreaux	gauthreaux	ADJ
fnp-3050	1058	14	k	k	PROPN
fnp-3050	1058	15	,	,	PUNCT
fnp-3050	1058	16	thomas	thomas	PROPN
fnp-3050	1058	17	nm	nm	PROPN
fnp-3050	1058	18	,	,	PUNCT
fnp-3050	1058	19	chen	chen	PROPN
fnp-3050	1058	20	yc	yc	PROPN
fnp-3050	1058	21	,	,	PUNCT
fnp-3050	1058	22	kukull	kukull	PROPN
fnp-3050	1058	23	wa	wa	PROPN
fnp-3050	1058	24	(	(	PUNCT
fnp-3050	1058	25	2019	2019	NUM
fnp-3050	1058	26	)	)	PUNCT
fnp-3050	1058	27	clinical	clinical	ADJ
fnp-3050	1058	28	diagnoses	diagnosis	NOUN
fnp-3050	1058	29	among	among	ADP
fnp-3050	1058	30	individuals	individual	NOUN
fnp-3050	1058	31	with	with	ADP
fnp-3050	1058	32	primary	primary	ADJ
fnp-3050	1058	33	age	age	NOUN
fnp-3050	1058	34	-	-	PUNCT
fnp-3050	1058	35	related	relate	VERB
fnp-3050	1058	36	tauopathy	tauopathy	NOUN
fnp-3050	1058	37	versus	versus	ADP
fnp-3050	1058	38	alzheimer	alzheimer	PROPN
fnp-3050	1058	39	's	's	PART
fnp-3050	1058	40	neuropathology	neuropathology	NOUN
fnp-3050	1058	41	.	.	PUNCT
fnp-3050	1059	1	lab	lab	PROPN
fnp-3050	1059	2	invest	invest	VERB
fnp-3050	1059	3	99:1049	99:1049	NOUN
fnp-3050	1059	4	-	-	SYM
fnp-3050	1059	5	1055	1055	NUM
fnp-3050	1059	6	262	262	NUM
fnp-3050	1059	7	.	.	PUNCT
fnp-3050	1060	1	murray	murray	PROPN
fnp-3050	1060	2	me	i	PRON
fnp-3050	1060	3	,	,	PUNCT
fnp-3050	1060	4	graff	graff	PROPN
fnp-3050	1060	5	-	-	PUNCT
fnp-3050	1060	6	radford	radford	PROPN
fnp-3050	1060	7	nr	nr	PROPN
fnp-3050	1060	8	,	,	PUNCT
fnp-3050	1060	9	ross	ross	PROPN
fnp-3050	1060	10	oa	oa	PROPN
fnp-3050	1060	11	,	,	PUNCT
fnp-3050	1060	12	petersen	petersen	PROPN
fnp-3050	1060	13	rc	rc	PROPN
fnp-3050	1060	14	,	,	PUNCT
fnp-3050	1060	15	duara	duara	PROPN
fnp-3050	1060	16	r	r	PROPN
fnp-3050	1060	17	,	,	PUNCT
fnp-3050	1060	18	dickson	dickson	PROPN
fnp-3050	1060	19	dw	dw	PROPN
fnp-3050	1060	20	(	(	PUNCT
fnp-3050	1060	21	2011	2011	NUM
fnp-3050	1060	22	)	)	PUNCT
fnp-3050	1060	23	neuropathologically	neuropathologically	ADV
fnp-3050	1060	24	defined	define	VERB
fnp-3050	1060	25	subtypes	subtype	NOUN
fnp-3050	1060	26	of	of	ADP
fnp-3050	1060	27	alzheimer	alzheimer	PROPN
fnp-3050	1060	28	's	's	PART
fnp-3050	1060	29	disease	disease	NOUN
fnp-3050	1060	30	with	with	ADP
fnp-3050	1060	31	distinct	distinct	ADJ
fnp-3050	1060	32	clinical	clinical	ADJ
fnp-3050	1060	33	characteristics	characteristic	NOUN
fnp-3050	1060	34	:	:	PUNCT
fnp-3050	1060	35	a	a	DET
fnp-3050	1060	36	retrospective	retrospective	ADJ
fnp-3050	1060	37	study	study	NOUN
fnp-3050	1060	38	.	.	PUNCT
fnp-3050	1061	1	lancet	lancet	PROPN
fnp-3050	1061	2	neurol	neurol	PROPN
fnp-3050	1061	3	10:785	10:785	PROPN
fnp-3050	1061	4	-	-	SYM
fnp-3050	1061	5	796	796	NUM
fnp-3050	1061	6	263	263	NUM
fnp-3050	1061	7	.	.	PUNCT
fnp-3050	1062	1	lehmann	lehmann	PROPN
fnp-3050	1062	2	m	m	PROPN
fnp-3050	1062	3	,	,	PUNCT
fnp-3050	1062	4	ghosh	ghosh	PROPN
fnp-3050	1062	5	pm	pm	PROPN
fnp-3050	1062	6	,	,	PUNCT
fnp-3050	1062	7	madison	madison	PROPN
fnp-3050	1062	8	c	c	PROPN
fnp-3050	1062	9	,	,	PUNCT
fnp-3050	1062	10	laforce	laforce	NOUN
fnp-3050	1062	11	r	r	NOUN
fnp-3050	1062	12	,	,	PUNCT
fnp-3050	1062	13	jr	jr	PROPN
fnp-3050	1062	14	.	.	PROPN
fnp-3050	1062	15	,	,	PUNCT
fnp-3050	1062	16	corbetta	corbetta	NOUN
fnp-3050	1062	17	-	-	PUNCT
fnp-3050	1062	18	rastelli	rastelli	NOUN
fnp-3050	1062	19	c	c	NOUN
fnp-3050	1062	20	,	,	PUNCT
fnp-3050	1062	21	weiner	weiner	NOUN
fnp-3050	1062	22	mw	mw	PROPN
fnp-3050	1062	23	,	,	PUNCT
fnp-3050	1062	24	greicius	greicius	PROPN
fnp-3050	1062	25	md	md	PROPN
fnp-3050	1062	26	,	,	PUNCT
fnp-3050	1062	27	seeley	seeley	PROPN
fnp-3050	1062	28	ww	ww	PROPN
fnp-3050	1062	29	,	,	PUNCT
fnp-3050	1062	30	gorno	gorno	NOUN
fnp-3050	1062	31	-	-	PUNCT
fnp-3050	1062	32	tempini	tempini	PROPN
fnp-3050	1062	33	ml	ml	PROPN
fnp-3050	1062	34	,	,	PUNCT
fnp-3050	1062	35	rosen	rosen	PROPN
fnp-3050	1062	36	hj	hj	PROPN
fnp-3050	1062	37	,	,	PUNCT
fnp-3050	1062	38	miller	miller	PROPN
fnp-3050	1062	39	bl	bl	PROPN
fnp-3050	1062	40	,	,	PUNCT
fnp-3050	1062	41	jagust	jagust	PROPN
fnp-3050	1062	42	wj	wj	PROPN
fnp-3050	1062	43	,	,	PUNCT
fnp-3050	1062	44	rabinovici	rabinovici	NOUN
fnp-3050	1062	45	gd	gd	PROPN
fnp-3050	1062	46	(	(	PUNCT
fnp-3050	1062	47	2013	2013	NUM
fnp-3050	1062	48	)	)	PUNCT
fnp-3050	1062	49	diverging	diverge	VERB
fnp-3050	1062	50	patterns	pattern	NOUN
fnp-3050	1062	51	of	of	ADP
fnp-3050	1062	52	amyloid	amyloid	NOUN
fnp-3050	1062	53	deposition	deposition	NOUN
fnp-3050	1062	54	and	and	CCONJ
fnp-3050	1062	55	hypometabolism	hypometabolism	NOUN
fnp-3050	1062	56	in	in	ADP
fnp-3050	1062	57	clinical	clinical	ADJ
fnp-3050	1062	58	variants	variant	NOUN
fnp-3050	1062	59	of	of	ADP
fnp-3050	1062	60	probable	probable	ADJ
fnp-3050	1062	61	alzheimer	alzheimer	PROPN
fnp-3050	1062	62	's	's	PART
fnp-3050	1062	63	disease	disease	NOUN
fnp-3050	1062	64	.	.	PUNCT
fnp-3050	1063	1	brain	brain	NOUN
fnp-3050	1063	2	136:844	136:844	NUM
fnp-3050	1063	3	-	-	PUNCT
fnp-3050	1063	4	858	858	NUM
fnp-3050	1063	5	264	264	NUM
fnp-3050	1063	6	.	.	PUNCT
fnp-3050	1064	1	rabinovici	rabinovici	PROPN
fnp-3050	1064	2	gd	gd	PROPN
fnp-3050	1064	3	,	,	PUNCT
fnp-3050	1064	4	furst	furst	PROPN
fnp-3050	1064	5	aj	aj	PROPN
fnp-3050	1064	6	,	,	PUNCT
fnp-3050	1064	7	alkalay	alkalay	VERB
fnp-3050	1064	8	a	a	PRON
fnp-3050	1064	9	,	,	PUNCT
fnp-3050	1064	10	racine	racine	PROPN
fnp-3050	1064	11	ca	ca	PROPN
fnp-3050	1064	12	,	,	PUNCT
fnp-3050	1064	13	o'neil	o'neil	PROPN
fnp-3050	1064	14	jp	jp	PROPN
fnp-3050	1064	15	,	,	PUNCT
fnp-3050	1064	16	janabi	janabi	PROPN
fnp-3050	1064	17	m	m	PROPN
fnp-3050	1064	18	,	,	PUNCT
fnp-3050	1064	19	baker	baker	PROPN
fnp-3050	1064	20	sl	sl	PROPN
fnp-3050	1064	21	,	,	PUNCT
fnp-3050	1064	22	agarwal	agarwal	PROPN
fnp-3050	1064	23	n	n	CCONJ
fnp-3050	1064	24	,	,	PUNCT
fnp-3050	1064	25	bonasera	bonasera	NOUN
fnp-3050	1064	26	sj	sj	PROPN
fnp-3050	1064	27	,	,	PUNCT
fnp-3050	1064	28	mormino	mormino	PROPN
fnp-3050	1064	29	ec	ec	PROPN
fnp-3050	1064	30	,	,	PUNCT
fnp-3050	1064	31	weiner	weiner	NOUN
fnp-3050	1064	32	mw	mw	PROPN
fnp-3050	1064	33	,	,	PUNCT
fnp-3050	1064	34	gorno	gorno	NOUN
fnp-3050	1064	35	-	-	PUNCT
fnp-3050	1064	36	tempini	tempini	PROPN
fnp-3050	1064	37	ml	ml	PROPN
fnp-3050	1064	38	,	,	PUNCT
fnp-3050	1064	39	rosen	rosen	PROPN
fnp-3050	1064	40	hj	hj	PROPN
fnp-3050	1064	41	,	,	PUNCT
fnp-3050	1064	42	miller	miller	PROPN
fnp-3050	1064	43	bl	bl	PROPN
fnp-3050	1064	44	,	,	PUNCT
fnp-3050	1064	45	jagust	jagust	ADP
fnp-3050	1064	46	wj	wj	PROPN
fnp-3050	1064	47	(	(	PUNCT
fnp-3050	1064	48	2010	2010	NUM
fnp-3050	1064	49	)	)	PUNCT
fnp-3050	1064	50	increased	increase	VERB
fnp-3050	1064	51	metabolic	metabolic	NOUN
fnp-3050	1064	52	vulnerability	vulnerability	NOUN
fnp-3050	1064	53	in	in	ADP
fnp-3050	1064	54	early	early	ADJ
fnp-3050	1064	55	-	-	PUNCT
fnp-3050	1064	56	onset	onset	NOUN
fnp-3050	1064	57	alzheimer	alzheimer	NOUN
fnp-3050	1064	58	's	's	PART
fnp-3050	1064	59	disease	disease	NOUN
fnp-3050	1064	60	is	be	AUX
fnp-3050	1064	61	not	not	PART
fnp-3050	1064	62	related	relate	VERB
fnp-3050	1064	63	to	to	ADP
fnp-3050	1064	64	amyloid	amyloid	NOUN
fnp-3050	1064	65	burden	burden	NOUN
fnp-3050	1064	66	.	.	PUNCT
fnp-3050	1065	1	brain	brain	NOUN
fnp-3050	1065	2	133:512	133:512	NOUN
fnp-3050	1065	3	-	-	PUNCT
fnp-3050	1065	4	528	528	NUM
fnp-3050	1065	5	265	265	NUM
fnp-3050	1065	6	.	.	PUNCT
fnp-3050	1066	1	iaccarino	iaccarino	PROPN
fnp-3050	1066	2	l	l	PROPN
fnp-3050	1066	3	,	,	PUNCT
fnp-3050	1066	4	tammewar	tammewar	NOUN
fnp-3050	1066	5	g	g	NOUN
fnp-3050	1066	6	,	,	PUNCT
fnp-3050	1066	7	ayakta	ayakta	NOUN
fnp-3050	1066	8	n	n	CCONJ
fnp-3050	1066	9	,	,	PUNCT
fnp-3050	1066	10	baker	baker	PROPN
fnp-3050	1066	11	sl	sl	PROPN
fnp-3050	1066	12	,	,	PUNCT
fnp-3050	1066	13	bejanin	bejanin	PROPN
fnp-3050	1066	14	a	a	NOUN
fnp-3050	1066	15	,	,	PUNCT
fnp-3050	1066	16	boxer	boxer	PROPN
fnp-3050	1066	17	al	al	PROPN
fnp-3050	1066	18	,	,	PUNCT
fnp-3050	1066	19	gorno	gorno	PROPN
fnp-3050	1066	20	-	-	PUNCT
fnp-3050	1066	21	tempini	tempini	PROPN
fnp-3050	1066	22	ml	ml	NOUN
fnp-3050	1066	23	,	,	PUNCT
fnp-3050	1066	24	janabi	janabi	PROPN
fnp-3050	1066	25	m	m	PROPN
fnp-3050	1066	26	,	,	PUNCT
fnp-3050	1066	27	kramer	kramer	PROPN
fnp-3050	1066	28	jh	jh	PROPN
fnp-3050	1066	29	,	,	PUNCT
fnp-3050	1066	30	lazaris	lazaris	PROPN
fnp-3050	1066	31	a	a	PROPN
fnp-3050	1066	32	,	,	PUNCT
fnp-3050	1066	33	lockhart	lockhart	PROPN
fnp-3050	1066	34	sn	sn	PROPN
fnp-3050	1066	35	,	,	PUNCT
fnp-3050	1066	36	miller	miller	PROPN
fnp-3050	1066	37	bl	bl	PROPN
fnp-3050	1066	38	,	,	PUNCT
fnp-3050	1066	39	miller	miller	PROPN
fnp-3050	1066	40	za	za	PROPN
fnp-3050	1066	41	,	,	PUNCT
fnp-3050	1066	42	o'neil	o'neil	PROPN
fnp-3050	1066	43	jp	jp	PROPN
fnp-3050	1066	44	,	,	PUNCT
fnp-3050	1066	45	ossenkoppele	ossenkoppele	PROPN
fnp-3050	1066	46	r	r	PROPN
fnp-3050	1066	47	,	,	PUNCT
fnp-3050	1066	48	rosen	rosen	PROPN
fnp-3050	1066	49	hj	hj	PROPN
fnp-3050	1066	50	,	,	PUNCT
fnp-3050	1066	51	schonhaut	schonhaut	PROPN
fnp-3050	1066	52	dr	dr	PROPN
fnp-3050	1066	53	,	,	PUNCT
fnp-3050	1066	54	jagust	jagust	PROPN
fnp-3050	1066	55	wj	wj	PROPN
fnp-3050	1066	56	,	,	PUNCT
fnp-3050	1066	57	rabinovici	rabinovici	NOUN
fnp-3050	1066	58	gd	gd	PROPN
fnp-3050	1066	59	(	(	PUNCT
fnp-3050	1066	60	2017	2017	NUM
fnp-3050	1066	61	)	)	PUNCT
fnp-3050	1066	62	local	local	ADJ
fnp-3050	1066	63	and	and	CCONJ
fnp-3050	1066	64	distant	distant	ADJ
fnp-3050	1066	65	relationships	relationship	NOUN
fnp-3050	1066	66	between	between	ADP
fnp-3050	1066	67	amyloid	amyloid	NOUN
fnp-3050	1066	68	,	,	PUNCT
fnp-3050	1066	69	tau	tau	PROPN
fnp-3050	1066	70	and	and	CCONJ
fnp-3050	1066	71	neurodegeneration	neurodegeneration	NOUN
fnp-3050	1066	72	in	in	ADP
fnp-3050	1066	73	alzheimer	alzheimer	PROPN
fnp-3050	1066	74	's	's	PART
fnp-3050	1066	75	disease	disease	NOUN
fnp-3050	1066	76	.	.	PUNCT
fnp-3050	1067	1	neuroimage	neuroimage	PROPN
fnp-3050	1067	2	clin	clin	PROPN
fnp-3050	1067	3	17:452	17:452	PROPN
fnp-3050	1067	4	-	-	SYM
fnp-3050	1067	5	464	464	NUM
fnp-3050	1067	6	266	266	NUM
fnp-3050	1067	7	.	.	PUNCT
fnp-3050	1068	1	ossenkoppele	ossenkoppele	PROPN
fnp-3050	1068	2	r	r	PROPN
fnp-3050	1068	3	,	,	PUNCT
fnp-3050	1068	4	pijnenburg	pijnenburg	PROPN
fnp-3050	1068	5	ya	ya	PROPN
fnp-3050	1068	6	,	,	PUNCT
fnp-3050	1068	7	perry	perry	PROPN
fnp-3050	1068	8	dc	dc	PROPN
fnp-3050	1068	9	,	,	PUNCT
fnp-3050	1068	10	cohn	cohn	PROPN
fnp-3050	1068	11	-	-	PUNCT
fnp-3050	1068	12	sheehy	sheehy	PROPN
fnp-3050	1068	13	bi	bi	PROPN
fnp-3050	1068	14	,	,	PUNCT
fnp-3050	1068	15	scheltens	schelten	VERB
fnp-3050	1068	16	nm	nm	ADP
fnp-3050	1068	17	,	,	PUNCT
fnp-3050	1068	18	vogel	vogel	PROPN
fnp-3050	1068	19	jw	jw	PROPN
fnp-3050	1068	20	,	,	PUNCT
fnp-3050	1068	21	kramer	kramer	PROPN
fnp-3050	1068	22	jh	jh	PROPN
fnp-3050	1068	23	,	,	PUNCT
fnp-3050	1068	24	van	van	PROPN
fnp-3050	1068	25	der	der	PROPN
fnp-3050	1068	26	vlies	vlie	NOUN
fnp-3050	1068	27	ae	ae	PROPN
fnp-3050	1068	28	,	,	PUNCT
fnp-3050	1068	29	la	la	PROPN
fnp-3050	1068	30	joie	joie	PROPN
fnp-3050	1068	31	r	r	PROPN
fnp-3050	1068	32	,	,	PUNCT
fnp-3050	1068	33	rosen	rosen	PROPN
fnp-3050	1068	34	hj	hj	PROPN
fnp-3050	1068	35	,	,	PUNCT
fnp-3050	1068	36	van	van	PROPN
fnp-3050	1068	37	der	der	PROPN
fnp-3050	1068	38	flier	flier	PROPN
fnp-3050	1068	39	wm	wm	PROPN
fnp-3050	1068	40	,	,	PUNCT
fnp-3050	1068	41	grinberg	grinberg	PROPN
fnp-3050	1068	42	lt	lt	PROPN
fnp-3050	1068	43	,	,	PUNCT
fnp-3050	1068	44	rozemuller	rozemuller	PROPN
fnp-3050	1068	45	aj	aj	PROPN
fnp-3050	1068	46	,	,	PUNCT
fnp-3050	1068	47	huang	huang	PROPN
fnp-3050	1068	48	ej	ej	PROPN
fnp-3050	1068	49	,	,	PUNCT
fnp-3050	1068	50	van	van	PROPN
fnp-3050	1068	51	berckel	berckel	NOUN
fnp-3050	1068	52	bn	bn	PROPN
fnp-3050	1068	53	,	,	PUNCT
fnp-3050	1068	54	miller	miller	PROPN
fnp-3050	1068	55	bl	bl	PROPN
fnp-3050	1068	56	,	,	PUNCT
fnp-3050	1068	57	barkhof	barkhof	PROPN
fnp-3050	1068	58	f	f	PROPN
fnp-3050	1068	59	,	,	PUNCT
fnp-3050	1068	60	jagust	jagust	PROPN
fnp-3050	1068	61	wj	wj	PROPN
fnp-3050	1068	62	,	,	PUNCT
fnp-3050	1068	63	scheltens	schelten	VERB
fnp-3050	1068	64	p	p	PROPN
fnp-3050	1068	65	,	,	PUNCT
fnp-3050	1068	66	seeley	seeley	PROPN
fnp-3050	1068	67	ww	ww	PROPN
fnp-3050	1068	68	,	,	PUNCT
fnp-3050	1068	69	rabinovici	rabinovici	NOUN
fnp-3050	1068	70	gd	gd	PROPN
fnp-3050	1068	71	(	(	PUNCT
fnp-3050	1068	72	2015	2015	NUM
fnp-3050	1068	73	)	)	PUNCT
fnp-3050	1068	74	the	the	DET
fnp-3050	1068	75	behavioural	behavioural	ADJ
fnp-3050	1068	76	/	/	SYM
fnp-3050	1068	77	dysexecutive	dysexecutive	ADJ
fnp-3050	1068	78	variant	variant	NOUN
fnp-3050	1068	79	of	of	ADP
fnp-3050	1068	80	alzheimer	alzheimer	PROPN
fnp-3050	1068	81	's	's	PART
fnp-3050	1068	82	disease	disease	NOUN
fnp-3050	1068	83	:	:	PUNCT
fnp-3050	1068	84	clinical	clinical	ADJ
fnp-3050	1068	85	,	,	PUNCT
fnp-3050	1068	86	neuroimaging	neuroimaging	ADJ
fnp-3050	1068	87	and	and	CCONJ
fnp-3050	1068	88	pathological	pathological	ADJ
fnp-3050	1068	89	features	feature	NOUN
fnp-3050	1068	90	.	.	PUNCT
fnp-3050	1069	1	brain	brain	NOUN
fnp-3050	1069	2	138:2732	138:2732	PROPN
fnp-3050	1069	3	-	-	SYM
fnp-3050	1069	4	2749	2749	NUM
fnp-3050	1069	5	267	267	NUM
fnp-3050	1069	6	.	.	PUNCT
fnp-3050	1069	7	tetzloff	tetzloff	PROPN
fnp-3050	1070	1	ka	ka	PROPN
fnp-3050	1070	2	,	,	PUNCT
fnp-3050	1070	3	graff	graff	PROPN
fnp-3050	1070	4	-	-	PUNCT
fnp-3050	1070	5	radford	radford	PROPN
fnp-3050	1070	6	j	j	PROPN
fnp-3050	1070	7	,	,	PUNCT
fnp-3050	1070	8	martin	martin	PROPN
fnp-3050	1070	9	pr	pr	PROPN
fnp-3050	1070	10	,	,	PUNCT
fnp-3050	1070	11	tosakulwong	tosakulwong	ADP
fnp-3050	1070	12	n	n	CCONJ
fnp-3050	1070	13	,	,	PUNCT
fnp-3050	1070	14	machulda	machulda	PROPN
fnp-3050	1070	15	mm	mm	PROPN
fnp-3050	1070	16	,	,	PUNCT
fnp-3050	1070	17	duffy	duffy	PROPN
fnp-3050	1070	18	jr	jr	PROPN
fnp-3050	1070	19	,	,	PUNCT
fnp-3050	1070	20	clark	clark	PROPN
fnp-3050	1070	21	hm	hm	PROPN
fnp-3050	1070	22	,	,	PUNCT
fnp-3050	1070	23	senjem	senjem	VERB
fnp-3050	1070	24	ml	ml	ADP
fnp-3050	1070	25	,	,	PUNCT
fnp-3050	1070	26	schwarz	schwarz	PROPN
fnp-3050	1070	27	cg	cg	PROPN
fnp-3050	1070	28	,	,	PUNCT
fnp-3050	1070	29	spychalla	spychalla	PROPN
fnp-3050	1070	30	aj	aj	PROPN
fnp-3050	1070	31	,	,	PUNCT
fnp-3050	1070	32	drubach	drubach	PROPN
fnp-3050	1070	33	da	da	PROPN
fnp-3050	1070	34	,	,	PUNCT
fnp-3050	1070	35	jack	jack	PROPN
fnp-3050	1070	36	cr	cr	PROPN
fnp-3050	1070	37	,	,	PUNCT
fnp-3050	1070	38	lowe	lowe	PROPN
fnp-3050	1070	39	vj	vj	PROPN
fnp-3050	1070	40	,	,	PUNCT
fnp-3050	1070	41	josephs	josephs	PROPN
fnp-3050	1070	42	ka	ka	PROPN
fnp-3050	1070	43	,	,	PUNCT
fnp-3050	1070	44	whitwell	whitwell	INTJ
fnp-3050	1070	45	jl	jl	X
fnp-3050	1070	46	(	(	PUNCT
fnp-3050	1070	47	2018	2018	NUM
fnp-3050	1070	48	)	)	PUNCT
fnp-3050	1070	49	regional	regional	ADJ
fnp-3050	1070	50	distribution	distribution	NOUN
fnp-3050	1070	51	,	,	PUNCT
fnp-3050	1070	52	asymmetry	asymmetry	NOUN
fnp-3050	1070	53	,	,	PUNCT
fnp-3050	1070	54	and	and	CCONJ
fnp-3050	1070	55	clinical	clinical	ADJ
fnp-3050	1070	56	correlates	correlate	NOUN
fnp-3050	1070	57	of	of	ADP
fnp-3050	1070	58	tau	tau	PROPN
fnp-3050	1070	59	uptake	uptake	ADJ
fnp-3050	1070	60	on	on	ADP
fnp-3050	1070	61	[	[	X
fnp-3050	1070	62	18f]av-1451	18f]av-1451	NUM
fnp-3050	1070	63	pet	pet	NOUN
fnp-3050	1070	64	in	in	ADP
fnp-3050	1070	65	atypical	atypical	ADJ
fnp-3050	1070	66	alzheimer	alzheimer	PROPN
fnp-3050	1070	67	's	's	PART
fnp-3050	1070	68	disease	disease	NOUN
fnp-3050	1070	69	.	.	PUNCT
fnp-3050	1071	1	j	j	PROPN
fnp-3050	1071	2	alzheimers	alzheimers	PROPN
fnp-3050	1071	3	dis	dis	PROPN
fnp-3050	1071	4	62:1713	62:1713	X
fnp-3050	1071	5	-	-	SYM
fnp-3050	1071	6	1724	1724	NUM
fnp-3050	1071	7	268	268	NUM
fnp-3050	1071	8	.	.	PUNCT
fnp-3050	1072	1	hwang	hwang	PROPN
fnp-3050	1072	2	j	j	PROPN
fnp-3050	1072	3	,	,	PUNCT
fnp-3050	1072	4	kim	kim	PROPN
fnp-3050	1072	5	cm	cm	PROPN
fnp-3050	1072	6	,	,	PUNCT
fnp-3050	1072	7	jeon	jeon	PROPN
fnp-3050	1072	8	s	s	PROPN
fnp-3050	1072	9	,	,	PUNCT
fnp-3050	1072	10	lee	lee	PROPN
fnp-3050	1072	11	jm	jm	PROPN
fnp-3050	1072	12	,	,	PUNCT
fnp-3050	1072	13	hong	hong	PROPN
fnp-3050	1072	14	yj	yj	PROPN
fnp-3050	1072	15	,	,	PUNCT
fnp-3050	1072	16	roh	roh	PROPN
fnp-3050	1072	17	jh	jh	PROPN
fnp-3050	1072	18	,	,	PUNCT
fnp-3050	1072	19	lee	lee	PROPN
fnp-3050	1072	20	jh	jh	PROPN
fnp-3050	1072	21	,	,	PUNCT
fnp-3050	1072	22	koh	koh	PROPN
fnp-3050	1072	23	jy	jy	PROPN
fnp-3050	1072	24	,	,	PUNCT
fnp-3050	1072	25	na	na	INTJ
fnp-3050	1072	26	dl	dl	PROPN
fnp-3050	1072	27	(	(	PUNCT
fnp-3050	1072	28	2015	2015	NUM
fnp-3050	1072	29	)	)	PUNCT
fnp-3050	1072	30	prediction	prediction	NOUN
fnp-3050	1072	31	of	of	ADP
fnp-3050	1072	32	alzheimer	alzheimer	PROPN
fnp-3050	1072	33	's	's	PART
fnp-3050	1072	34	disease	disease	NOUN
fnp-3050	1072	35	pathophysiology	pathophysiology	NOUN
fnp-3050	1072	36	based	base	VERB
fnp-3050	1072	37	on	on	ADP
fnp-3050	1072	38	cortical	cortical	ADJ
fnp-3050	1072	39	thickness	thickness	NOUN
fnp-3050	1072	40	patterns	pattern	NOUN
fnp-3050	1072	41	.	.	PUNCT
fnp-3050	1073	1	alzheimers	alzheimers	PROPN
fnp-3050	1073	2	dement	dement	PROPN
fnp-3050	1073	3	(	(	PUNCT
fnp-3050	1073	4	amst	amst	NOUN
fnp-3050	1073	5	)	)	PUNCT
fnp-3050	1073	6	2:58	2:58	NUM
fnp-3050	1073	7	-	-	SYM
fnp-3050	1073	8	67	67	NUM
fnp-3050	1073	9	269	269	NUM
fnp-3050	1073	10	.	.	PUNCT
fnp-3050	1074	1	whitwell	whitwell	PROPN
fnp-3050	1074	2	jl	jl	PROPN
fnp-3050	1074	3	,	,	PUNCT
fnp-3050	1074	4	dickson	dickson	PROPN
fnp-3050	1074	5	dw	dw	PROPN
fnp-3050	1074	6	,	,	PUNCT
fnp-3050	1074	7	murray	murray	VERB
fnp-3050	1074	8	me	i	PRON
fnp-3050	1074	9	,	,	PUNCT
fnp-3050	1074	10	weigand	weigand	NOUN
fnp-3050	1074	11	sd	sd	NOUN
fnp-3050	1074	12	,	,	PUNCT
fnp-3050	1074	13	tosakulwong	tosakulwong	ADP
fnp-3050	1074	14	n	n	CCONJ
fnp-3050	1074	15	,	,	PUNCT
fnp-3050	1074	16	senjem	senjem	NOUN
fnp-3050	1074	17	ml	ml	ADP
fnp-3050	1074	18	,	,	PUNCT
fnp-3050	1074	19	knopman	knopman	NOUN
fnp-3050	1074	20	ds	ds	PROPN
fnp-3050	1074	21	,	,	PUNCT
fnp-3050	1074	22	boeve	boeve	NOUN
fnp-3050	1074	23	bf	bf	PROPN
fnp-3050	1074	24	,	,	PUNCT
fnp-3050	1074	25	parisi	parisi	PROPN
fnp-3050	1074	26	je	je	PROPN
fnp-3050	1074	27	,	,	PUNCT
fnp-3050	1074	28	petersen	petersen	PROPN
fnp-3050	1074	29	rc	rc	PROPN
fnp-3050	1074	30	,	,	PUNCT
fnp-3050	1074	31	jack	jack	PROPN
fnp-3050	1074	32	cr	cr	PROPN
fnp-3050	1074	33	,	,	PUNCT
fnp-3050	1074	34	jr	jr	PROPN
fnp-3050	1074	35	.	.	PROPN
fnp-3050	1074	36	,	,	PUNCT
fnp-3050	1074	37	josephs	josephs	PROPN
fnp-3050	1074	38	ka	ka	PROPN
fnp-3050	1074	39	(	(	PUNCT
fnp-3050	1074	40	2012	2012	NUM
fnp-3050	1074	41	)	)	PUNCT
fnp-3050	1074	42	neuroimaging	neuroimaging	NOUN
fnp-3050	1074	43	correlates	correlate	VERB
fnp-3050	1074	44	of	of	ADP
fnp-3050	1074	45	pathologically	pathologically	ADV
fnp-3050	1074	46	defined	define	VERB
fnp-3050	1074	47	subtypes	subtype	NOUN
fnp-3050	1074	48	of	of	ADP
fnp-3050	1074	49	alzheimer	alzheimer	PROPN
fnp-3050	1074	50	's	's	PART
fnp-3050	1074	51	disease	disease	NOUN
fnp-3050	1074	52	:	:	PUNCT
fnp-3050	1074	53	a	a	DET
fnp-3050	1074	54	case	case	NOUN
fnp-3050	1074	55	-	-	PUNCT
fnp-3050	1074	56	control	control	NOUN
fnp-3050	1074	57	study	study	NOUN
fnp-3050	1074	58	.	.	PUNCT
fnp-3050	1075	1	lancet	lancet	PROPN
fnp-3050	1075	2	neurol	neurol	PROPN
fnp-3050	1075	3	11:868	11:868	PROPN
fnp-3050	1075	4	-	-	SYM
fnp-3050	1075	5	877	877	NUM
fnp-3050	1075	6	270	270	NUM
fnp-3050	1075	7	.	.	PUNCT
fnp-3050	1076	1	jellinger	jellinger	PROPN
fnp-3050	1076	2	ka	ka	PROPN
fnp-3050	1076	3	(	(	PUNCT
fnp-3050	1076	4	2012	2012	NUM
fnp-3050	1076	5	)	)	PUNCT
fnp-3050	1076	6	neuropathological	neuropathological	ADJ
fnp-3050	1076	7	subtypes	subtype	NOUN
fnp-3050	1076	8	of	of	ADP
fnp-3050	1076	9	alzheimer	alzheimer	PROPN
fnp-3050	1076	10	's	's	PART
fnp-3050	1076	11	disease	disease	NOUN
fnp-3050	1076	12	(	(	PUNCT
fnp-3050	1076	13	correspondence	correspondence	NOUN
fnp-3050	1076	14	)	)	PUNCT
fnp-3050	1076	15	.	.	PUNCT
fnp-3050	1077	1	acta	acta	PROPN
fnp-3050	1077	2	neuropathol	neuropathol	PROPN
fnp-3050	1077	3	123:153	123:153	PROPN
fnp-3050	1077	4	-	-	PUNCT
fnp-3050	1077	5	154	154	NUM
fnp-3050	1077	6	271	271	NUM
fnp-3050	1077	7	.	.	PUNCT
fnp-3050	1078	1	mcaleese	mcaleese	PROPN
fnp-3050	1078	2	ke	ke	PROPN
fnp-3050	1078	3	,	,	PUNCT
fnp-3050	1078	4	walker	walker	PROPN
fnp-3050	1078	5	l	l	PROPN
fnp-3050	1078	6	,	,	PUNCT
fnp-3050	1078	7	graham	graham	PROPN
fnp-3050	1078	8	s	s	PROPN
fnp-3050	1078	9	,	,	PUNCT
fnp-3050	1078	10	moya	moya	PROPN
fnp-3050	1078	11	elj	elj	PROPN
fnp-3050	1078	12	,	,	PUNCT
fnp-3050	1078	13	johnson	johnson	PROPN
fnp-3050	1078	14	m	m	PROPN
fnp-3050	1078	15	,	,	PUNCT
fnp-3050	1078	16	erskine	erskine	PROPN
fnp-3050	1078	17	d	d	PROPN
fnp-3050	1078	18	,	,	PUNCT
fnp-3050	1078	19	colloby	colloby	NOUN
fnp-3050	1078	20	sj	sj	PROPN
fnp-3050	1078	21	,	,	PUNCT
fnp-3050	1078	22	dey	dey	PROPN
fnp-3050	1078	23	m	m	PROPN
fnp-3050	1078	24	,	,	PUNCT
fnp-3050	1078	25	martin	martin	PROPN
fnp-3050	1078	26	-	-	PUNCT
fnp-3050	1078	27	ruiz	ruiz	NOUN
fnp-3050	1078	28	c	c	PROPN
fnp-3050	1078	29	,	,	PUNCT
fnp-3050	1078	30	taylor	taylor	PROPN
fnp-3050	1078	31	jp	jp	PROPN
fnp-3050	1078	32	,	,	PUNCT
fnp-3050	1078	33	thomas	thomas	PROPN
fnp-3050	1078	34	aj	aj	PROPN
fnp-3050	1078	35	,	,	PUNCT
fnp-3050	1078	36	mckeith	mckeith	PROPN
fnp-3050	1078	37	ig	ig	PROPN
fnp-3050	1078	38	,	,	PUNCT
fnp-3050	1078	39	de	de	PROPN
fnp-3050	1078	40	carli	carli	PROPN
fnp-3050	1078	41	c	c	PROPN
fnp-3050	1078	42	,	,	PUNCT
fnp-3050	1078	43	attems	attem	VERB
fnp-3050	1078	44	j	j	PROPN
fnp-3050	1078	45	(	(	PUNCT
fnp-3050	1078	46	2017	2017	NUM
fnp-3050	1078	47	)	)	PUNCT
fnp-3050	1078	48	parietal	parietal	ADJ
fnp-3050	1078	49	white	white	ADJ
fnp-3050	1078	50	matter	matter	NOUN
fnp-3050	1078	51	lesions	lesion	NOUN
fnp-3050	1078	52	in	in	ADP
fnp-3050	1078	53	alzheimer	alzheimer	PROPN
fnp-3050	1078	54	's	's	PART
fnp-3050	1078	55	disease	disease	NOUN
fnp-3050	1078	56	are	be	AUX
fnp-3050	1078	57	associated	associate	VERB
fnp-3050	1078	58	with	with	ADP
fnp-3050	1078	59	cortical	cortical	ADJ
fnp-3050	1078	60	neurodegenerative	neurodegenerative	ADJ
fnp-3050	1078	61	pathology	pathology	NOUN
fnp-3050	1078	62	,	,	PUNCT
fnp-3050	1078	63	but	but	CCONJ
fnp-3050	1078	64	not	not	PART
fnp-3050	1078	65	with	with	ADP
fnp-3050	1078	66	small	small	ADJ
fnp-3050	1078	67	vessel	vessel	NOUN
fnp-3050	1078	68	disease	disease	NOUN
fnp-3050	1078	69	.	.	PUNCT
fnp-3050	1079	1	acta	acta	PROPN
fnp-3050	1079	2	neuropathol	neuropathol	PROPN
fnp-3050	1079	3	134:459	134:459	PROPN
fnp-3050	1079	4	-	-	SYM
fnp-3050	1079	5	473	473	NUM
fnp-3050	1079	6	272	272	NUM
fnp-3050	1079	7	.	.	PUNCT
fnp-3050	1080	1	strain	strain	PROPN
fnp-3050	1080	2	jf	jf	PROPN
fnp-3050	1080	3	,	,	PUNCT
fnp-3050	1080	4	smith	smith	PROPN
fnp-3050	1080	5	rx	rx	PROPN
fnp-3050	1080	6	,	,	PUNCT
fnp-3050	1080	7	beaumont	beaumont	PROPN
fnp-3050	1080	8	h	h	PROPN
fnp-3050	1080	9	,	,	PUNCT
fnp-3050	1080	10	roe	roe	PROPN
fnp-3050	1080	11	cm	cm	PROPN
fnp-3050	1080	12	,	,	PUNCT
fnp-3050	1080	13	gordon	gordon	PROPN
fnp-3050	1080	14	ba	ba	PROPN
fnp-3050	1080	15	,	,	PUNCT
fnp-3050	1080	16	mishra	mishra	PROPN
fnp-3050	1080	17	s	s	PROPN
fnp-3050	1080	18	,	,	PUNCT
fnp-3050	1080	19	adeyemo	adeyemo	PROPN
fnp-3050	1080	20	b	b	PROPN
fnp-3050	1080	21	,	,	PUNCT
fnp-3050	1080	22	christensen	christensen	PROPN
fnp-3050	1080	23	jj	jj	PROPN
fnp-3050	1080	24	,	,	PUNCT
fnp-3050	1080	25	su	su	PROPN
fnp-3050	1080	26	y	y	PROPN
fnp-3050	1080	27	,	,	PUNCT
fnp-3050	1080	28	morris	morris	PROPN
fnp-3050	1080	29	jc	jc	PROPN
fnp-3050	1080	30	,	,	PUNCT
fnp-3050	1080	31	benzinger	benzinger	PROPN
fnp-3050	1080	32	tls	tls	PROPN
fnp-3050	1080	33	,	,	PUNCT
fnp-3050	1080	34	ances	ance	NOUN
fnp-3050	1080	35	bm	bm	PROPN
fnp-3050	1080	36	(	(	PUNCT
fnp-3050	1080	37	2018	2018	NUM
fnp-3050	1080	38	)	)	PUNCT
fnp-3050	1080	39	loss	loss	NOUN
fnp-3050	1080	40	of	of	ADP
fnp-3050	1080	41	white	white	ADJ
fnp-3050	1080	42	matter	matter	NOUN
fnp-3050	1080	43	integrity	integrity	NOUN
fnp-3050	1080	44	reflects	reflect	VERB
fnp-3050	1080	45	tau	tau	PROPN
fnp-3050	1080	46	accumulation	accumulation	NOUN
fnp-3050	1080	47	in	in	ADP
fnp-3050	1080	48	alzheimer	alzheimer	PROPN
fnp-3050	1080	49	disease	disease	NOUN
fnp-3050	1080	50	defined	define	VERB
fnp-3050	1080	51	regions	region	NOUN
fnp-3050	1080	52	.	.	PUNCT
fnp-3050	1081	1	neurology	neurology	NOUN
fnp-3050	1081	2	91	91	NUM
fnp-3050	1081	3	:	:	PUNCT
fnp-3050	1081	4	e313	e313	PROPN
fnp-3050	1081	5	-	-	PUNCT
fnp-3050	1081	6	e318	e318	PROPN
fnp-3050	1081	7	273	273	NUM
fnp-3050	1081	8	.	.	PUNCT
fnp-3050	1082	1	arfanakis	arfanaki	NOUN
fnp-3050	1083	1	k	k	PROPN
fnp-3050	1083	2	,	,	PUNCT
fnp-3050	1083	3	evia	evia	PROPN
fnp-3050	1083	4	am	am	PROPN
fnp-3050	1083	5	,	,	PUNCT
fnp-3050	1083	6	leurgans	leurgans	PROPN
fnp-3050	1083	7	se	se	ADV
fnp-3050	1083	8	,	,	PUNCT
fnp-3050	1083	9	cardoso	cardoso	PROPN
fnp-3050	1083	10	lfc	lfc	PROPN
fnp-3050	1083	11	,	,	PUNCT
fnp-3050	1083	12	kulkarni	kulkarni	PROPN
fnp-3050	1083	13	a	a	PROPN
fnp-3050	1083	14	,	,	PUNCT
fnp-3050	1083	15	alqam	alqam	PROPN
fnp-3050	1083	16	n	n	CCONJ
fnp-3050	1083	17	,	,	PUNCT
fnp-3050	1083	18	lopes	lopes	PROPN
fnp-3050	1084	1	lf	lf	PROPN
fnp-3050	1084	2	,	,	PUNCT
fnp-3050	1084	3	vieira	vieira	PROPN
fnp-3050	1084	4	d	d	PROPN
fnp-3050	1084	5	,	,	PUNCT
fnp-3050	1084	6	bennett	bennett	PROPN
fnp-3050	1084	7	da	da	PROPN
fnp-3050	1084	8	,	,	PUNCT
fnp-3050	1084	9	schneider	schneider	PROPN
fnp-3050	1084	10	ja	ja	PROPN
fnp-3050	1084	11	(	(	PUNCT
fnp-3050	1084	12	2020	2020	NUM
fnp-3050	1084	13	)	)	PUNCT
fnp-3050	1085	1	neuropathologic	neuropathologic	NOUN
fnp-3050	1085	2	correlates	correlate	VERB
fnp-3050	1085	3	of	of	ADP
fnp-3050	1085	4	white	white	ADJ
fnp-3050	1085	5	matter	matter	NOUN
fnp-3050	1085	6	hyperintensities	hyperintensitie	NOUN
fnp-3050	1085	7	in	in	ADP
fnp-3050	1085	8	a	a	DET
fnp-3050	1085	9	community	community	NOUN
fnp-3050	1085	10	-	-	PUNCT
fnp-3050	1085	11	based	base	VERB
fnp-3050	1085	12	cohort	cohort	NOUN
fnp-3050	1085	13	of	of	ADP
fnp-3050	1085	14	older	old	ADJ
fnp-3050	1085	15	adults	adult	NOUN
fnp-3050	1085	16	.	.	PUNCT
fnp-3050	1086	1	j	j	PROPN
fnp-3050	1086	2	alzheimers	alzheimers	PROPN
fnp-3050	1086	3	dis	dis	PROPN
fnp-3050	1086	4	73:333	73:333	PROPN
fnp-3050	1086	5	-	-	SYM
fnp-3050	1086	6	345	345	NUM
fnp-3050	1086	7	274	274	NUM
fnp-3050	1086	8	.	.	PUNCT
fnp-3050	1087	1	mcaleese	mcaleese	PROPN
fnp-3050	1087	2	ke	ke	PROPN
fnp-3050	1087	3	,	,	PUNCT
fnp-3050	1087	4	colloby	colloby	NOUN
fnp-3050	1087	5	s	s	PART
fnp-3050	1087	6	,	,	PUNCT
fnp-3050	1087	7	attems	attem	VERB
fnp-3050	1087	8	j	j	PROPN
fnp-3050	1087	9	,	,	PUNCT
fnp-3050	1087	10	thomas	thomas	PROPN
fnp-3050	1087	11	a	a	PROPN
fnp-3050	1087	12	,	,	PUNCT
fnp-3050	1087	13	francis	francis	PROPN
fnp-3050	1087	14	pt	pt	PROPN
fnp-3050	1087	15	(	(	PUNCT
fnp-3050	1087	16	2020	2020	NUM
fnp-3050	1087	17	)	)	PUNCT
fnp-3050	1087	18	mixed	mixed	ADJ
fnp-3050	1087	19	brain	brain	NOUN
fnp-3050	1087	20	pathologies	pathology	NOUN
fnp-3050	1087	21	account	account	VERB
fnp-3050	1087	22	for	for	ADP
fnp-3050	1087	23	most	most	ADJ
fnp-3050	1087	24	dementia	dementia	NOUN
fnp-3050	1087	25	in	in	ADP
fnp-3050	1087	26	the	the	DET
fnp-3050	1087	27	brains	brain	NOUN
fnp-3050	1087	28	for	for	ADP
fnp-3050	1087	29	dementia	dementia	NOUN
fnp-3050	1087	30	research	research	NOUN
fnp-3050	1087	31	cohort	cohort	NOUN
fnp-3050	1087	32	(	(	PUNCT
fnp-3050	1087	33	abstract	abstract	ADJ
fnp-3050	1087	34	)	)	PUNCT
fnp-3050	1087	35	.	.	PUNCT
fnp-3050	1088	1	neuropathol	neuropathol	PROPN
fnp-3050	1088	2	appl	appl	PROPN
fnp-3050	1088	3	neurobiol	neurobiol	PROPN
fnp-3050	1088	4	46	46	NUM
fnp-3050	1088	5	(	(	PUNCT
fnp-3050	1088	6	suppl	suppl	ADJ
fnp-3050	1088	7	.	.	PUNCT
fnp-3050	1089	1	1):24	1):24	NUM
fnp-3050	1089	2	275	275	NUM
fnp-3050	1089	3	.	.	PUNCT
fnp-3050	1090	1	mcaleese	mcaleese	PROPN
fnp-3050	1090	2	ke	ke	PROPN
fnp-3050	1090	3	,	,	PUNCT
fnp-3050	1090	4	mohi	mohi	PROPN
fnp-3050	1090	5	m	m	PROPN
fnp-3050	1090	6	,	,	PUNCT
fnp-3050	1090	7	graham	graham	PROPN
fnp-3050	1090	8	s	s	PROPN
fnp-3050	1090	9	,	,	PUNCT
fnp-3050	1090	10	baker	baker	PROPN
fnp-3050	1090	11	g	g	PROPN
fnp-3050	1090	12	,	,	PUNCT
fnp-3050	1090	13	walker	walker	PROPN
fnp-3050	1090	14	l	l	PROPN
fnp-3050	1090	15	,	,	PUNCT
fnp-3050	1090	16	decarli	decarli	PROPN
fnp-3050	1090	17	c	c	NOUN
fnp-3050	1090	18	,	,	PUNCT
fnp-3050	1090	19	koss	koss	PROPN
fnp-3050	1090	20	d	d	PROPN
fnp-3050	1090	21	,	,	PUNCT
fnp-3050	1090	22	attems	attem	VERB
fnp-3050	1090	23	j	j	PROPN
fnp-3050	1090	24	(	(	PUNCT
fnp-3050	1090	25	2020	2020	NUM
fnp-3050	1090	26	)	)	PUNCT
fnp-3050	1090	27	the	the	DET
fnp-3050	1090	28	aetiology	aetiology	NOUN
fnp-3050	1090	29	of	of	ADP
fnp-3050	1090	30	frontal	frontal	ADJ
fnp-3050	1090	31	white	white	ADJ
fnp-3050	1090	32	matter	matter	NOUN
fnp-3050	1090	33	lesions	lesion	NOUN
fnp-3050	1090	34	in	in	ADP
fnp-3050	1090	35	alzheimer	alzheimer	PROPN
fnp-3050	1090	36	’s	’s	PART
fnp-3050	1090	37	disease	disease	NOUN
fnp-3050	1090	38	are	be	AUX
fnp-3050	1090	39	associated	associate	VERB
fnp-3050	1090	40	with	with	ADP
fnp-3050	1090	41	both	both	CCONJ
fnp-3050	1090	42	neurodegenerative	neurodegenerative	ADJ
fnp-3050	1090	43	and	and	CCONJ
fnp-3050	1090	44	ischemic	ischemic	ADJ
fnp-3050	1090	45	mechanisms	mechanism	NOUN
fnp-3050	1090	46	(	(	PUNCT
fnp-3050	1090	47	abstract	abstract	ADJ
fnp-3050	1090	48	)	)	PUNCT
fnp-3050	1090	49	.	.	PUNCT
fnp-3050	1091	1	neuropathol	neuropathol	PROPN
fnp-3050	1091	2	appl	appl	PROPN
fnp-3050	1091	3	neurobiol	neurobiol	PROPN
fnp-3050	1091	4	46	46	NUM
fnp-3050	1091	5	(	(	PUNCT
fnp-3050	1091	6	suppl	suppl	ADJ
fnp-3050	1091	7	.	.	PUNCT
fnp-3050	1092	1	1):15	1):15	NUM
fnp-3050	1092	2	276	276	NUM
fnp-3050	1092	3	.	.	PUNCT
fnp-3050	1093	1	ferreira	ferreira	PROPN
fnp-3050	1093	2	d	d	PROPN
fnp-3050	1093	3	,	,	PUNCT
fnp-3050	1093	4	verhagen	verhagen	PROPN
fnp-3050	1093	5	c	c	NOUN
fnp-3050	1093	6	,	,	PUNCT
fnp-3050	1093	7	hernandez	hernandez	PROPN
fnp-3050	1093	8	-	-	PUNCT
fnp-3050	1093	9	cabrera	cabrera	PROPN
fnp-3050	1093	10	ja	ja	PROPN
fnp-3050	1093	11	,	,	PUNCT
fnp-3050	1093	12	cavallin	cavallin	PROPN
fnp-3050	1093	13	l	l	PROPN
fnp-3050	1093	14	,	,	PUNCT
fnp-3050	1093	15	guo	guo	PROPN
fnp-3050	1093	16	cj	cj	PROPN
fnp-3050	1093	17	,	,	PUNCT
fnp-3050	1093	18	ekman	ekman	PROPN
fnp-3050	1093	19	u	u	PROPN
fnp-3050	1093	20	,	,	PUNCT
fnp-3050	1093	21	muehlboeck	muehlboeck	PROPN
fnp-3050	1093	22	js	js	PROPN
fnp-3050	1093	23	,	,	PUNCT
fnp-3050	1093	24	simmons	simmon	NOUN
fnp-3050	1093	25	a	a	PRON
fnp-3050	1093	26	,	,	PUNCT
fnp-3050	1093	27	barroso	barroso	PROPN
fnp-3050	1093	28	j	j	PROPN
fnp-3050	1093	29	,	,	PUNCT
fnp-3050	1093	30	wahlund	wahlund	PROPN
fnp-3050	1093	31	lo	lo	PROPN
fnp-3050	1093	32	,	,	PUNCT
fnp-3050	1093	33	westman	westman	NOUN
fnp-3050	1093	34	e	e	X
fnp-3050	1093	35	(	(	PUNCT
fnp-3050	1093	36	2017	2017	NUM
fnp-3050	1093	37	)	)	PUNCT
fnp-3050	1093	38	distinct	distinct	ADJ
fnp-3050	1093	39	subtypes	subtype	NOUN
fnp-3050	1093	40	of	of	ADP
fnp-3050	1093	41	alzheimer	alzheimer	PROPN
fnp-3050	1093	42	's	's	PART
fnp-3050	1093	43	disease	disease	NOUN
fnp-3050	1093	44	based	base	VERB
fnp-3050	1093	45	on	on	ADP
fnp-3050	1093	46	patterns	pattern	NOUN
fnp-3050	1093	47	of	of	ADP
fnp-3050	1093	48	brain	brain	NOUN
fnp-3050	1093	49	atrophy	atrophy	NOUN
fnp-3050	1093	50	:	:	PUNCT
fnp-3050	1093	51	longitudinal	longitudinal	ADJ
fnp-3050	1093	52	trajectories	trajectory	NOUN
fnp-3050	1093	53	and	and	CCONJ
fnp-3050	1093	54	clinical	clinical	ADJ
fnp-3050	1093	55	applications	application	NOUN
fnp-3050	1093	56	.	.	PUNCT
fnp-3050	1094	1	sci	sci	PROPN
fnp-3050	1094	2	rep	rep	PROPN
fnp-3050	1094	3	7:46263	7:46263	PROPN
fnp-3050	1094	4	277	277	NUM
fnp-3050	1094	5	.	.	PUNCT
fnp-3050	1095	1	ferreira	ferreira	PROPN
fnp-3050	1095	2	d	d	PROPN
fnp-3050	1095	3	,	,	PUNCT
fnp-3050	1095	4	pereira	pereira	PROPN
fnp-3050	1095	5	jb	jb	PROPN
fnp-3050	1095	6	,	,	PUNCT
fnp-3050	1095	7	volpe	volpe	PROPN
fnp-3050	1095	8	g	g	PROPN
fnp-3050	1095	9	,	,	PUNCT
fnp-3050	1095	10	westman	westman	NOUN
fnp-3050	1095	11	e	e	X
fnp-3050	1095	12	(	(	PUNCT
fnp-3050	1095	13	2019	2019	NUM
fnp-3050	1095	14	)	)	PUNCT
fnp-3050	1095	15	subtypes	subtype	NOUN
fnp-3050	1095	16	of	of	ADP
fnp-3050	1095	17	alzheimer	alzheimer	PROPN
fnp-3050	1095	18	's	's	PART
fnp-3050	1095	19	disease	disease	NOUN
fnp-3050	1095	20	display	display	VERB
fnp-3050	1095	21	distinct	distinct	ADJ
fnp-3050	1095	22	network	network	NOUN
fnp-3050	1095	23	abnormalities	abnormality	NOUN
fnp-3050	1095	24	extending	extend	VERB
fnp-3050	1095	25	beyond	beyond	ADP
fnp-3050	1095	26	their	their	PRON
fnp-3050	1095	27	pattern	pattern	NOUN
fnp-3050	1095	28	of	of	ADP
fnp-3050	1095	29	brain	brain	NOUN
fnp-3050	1095	30	atrophy	atrophy	NOUN
fnp-3050	1095	31	.	.	PUNCT
fnp-3050	1096	1	front	front	ADJ
fnp-3050	1096	2	neurol	neurol	PROPN
fnp-3050	1096	3	10:524	10:524	NUM
fnp-3050	1096	4	278	278	NUM
fnp-3050	1096	5	.	.	PUNCT
fnp-3050	1097	1	risacher	risacher	PROPN
fnp-3050	1097	2	sl	sl	PROPN
fnp-3050	1097	3	,	,	PUNCT
fnp-3050	1097	4	anderson	anderson	PROPN
fnp-3050	1097	5	wh	wh	PROPN
fnp-3050	1097	6	,	,	PUNCT
fnp-3050	1097	7	charil	charil	PROPN
fnp-3050	1097	8	a	a	DET
fnp-3050	1097	9	,	,	PUNCT
fnp-3050	1097	10	castelluccio	castelluccio	NOUN
fnp-3050	1097	11	pf	pf	PROPN
fnp-3050	1097	12	,	,	PUNCT
fnp-3050	1097	13	shcherbinin	shcherbinin	ADP
fnp-3050	1097	14	s	s	SYM
fnp-3050	1097	15	,	,	PUNCT
fnp-3050	1097	16	saykin	saykin	PROPN
fnp-3050	1097	17	aj	aj	PROPN
fnp-3050	1097	18	,	,	PUNCT
fnp-3050	1097	19	schwarz	schwarz	PROPN
fnp-3050	1097	20	aj	aj	PROPN
fnp-3050	1097	21	(	(	PUNCT
fnp-3050	1097	22	2017	2017	NUM
fnp-3050	1097	23	)	)	PUNCT
fnp-3050	1097	24	alzheimer	alzheimer	NOUN
fnp-3050	1097	25	disease	disease	NOUN
fnp-3050	1097	26	brain	brain	NOUN
fnp-3050	1097	27	atrophy	atrophy	NOUN
fnp-3050	1097	28	subtypes	subtype	NOUN
fnp-3050	1097	29	are	be	AUX
fnp-3050	1097	30	associated	associate	VERB
fnp-3050	1097	31	with	with	ADP
fnp-3050	1097	32	cognition	cognition	NOUN
fnp-3050	1097	33	and	and	CCONJ
fnp-3050	1097	34	rate	rate	NOUN
fnp-3050	1097	35	of	of	ADP
fnp-3050	1097	36	decline	decline	NOUN
fnp-3050	1097	37	.	.	PUNCT
fnp-3050	1098	1	neurology	neurology	NOUN
fnp-3050	1098	2	89:2176	89:2176	PROPN
fnp-3050	1098	3	-	-	PUNCT
fnp-3050	1098	4	2186	2186	NUM
fnp-3050	1098	5	279	279	NUM
fnp-3050	1098	6	.	.	PUNCT
fnp-3050	1099	1	lowe	lowe	PROPN
fnp-3050	1099	2	vj	vj	PROPN
fnp-3050	1099	3	,	,	PUNCT
fnp-3050	1099	4	lundt	lundt	PROPN
fnp-3050	1099	5	es	es	PROPN
fnp-3050	1099	6	,	,	PUNCT
fnp-3050	1099	7	albertson	albertson	PROPN
fnp-3050	1099	8	sm	sm	PROPN
fnp-3050	1099	9	,	,	PUNCT
fnp-3050	1099	10	min	min	PROPN
fnp-3050	1099	11	hk	hk	PROPN
fnp-3050	1099	12	,	,	PUNCT
fnp-3050	1099	13	fang	fang	PROPN
fnp-3050	1099	14	p	p	PROPN
fnp-3050	1099	15	,	,	PUNCT
fnp-3050	1099	16	przybelski	przybelski	PROPN
fnp-3050	1099	17	sa	sa	PROPN
fnp-3050	1099	18	,	,	PUNCT
fnp-3050	1099	19	senjem	senjem	VERB
fnp-3050	1099	20	ml	ml	ADP
fnp-3050	1099	21	,	,	PUNCT
fnp-3050	1099	22	schwarz	schwarz	PROPN
fnp-3050	1099	23	cg	cg	PROPN
fnp-3050	1099	24	,	,	PUNCT
fnp-3050	1099	25	kantarci	kantarci	PROPN
fnp-3050	1099	26	k	k	PROPN
fnp-3050	1099	27	,	,	PUNCT
fnp-3050	1099	28	boeve	boeve	PROPN
fnp-3050	1099	29	b	b	PROPN
fnp-3050	1099	30	,	,	PUNCT
fnp-3050	1099	31	jones	jones	PROPN
fnp-3050	1099	32	dt	dt	PROPN
fnp-3050	1099	33	,	,	PUNCT
fnp-3050	1099	34	reichard	reichard	PROPN
fnp-3050	1099	35	rr	rr	PROPN
fnp-3050	1099	36	,	,	PUNCT
fnp-3050	1099	37	tranovich	tranovich	PROPN
fnp-3050	1099	38	jf	jf	PROPN
fnp-3050	1099	39	,	,	PUNCT
fnp-3050	1099	40	hanna	hanna	PROPN
fnp-3050	1099	41	al	al	PROPN
fnp-3050	1099	42	-	-	PUNCT
fnp-3050	1099	43	shaikh	shaikh	PROPN
fnp-3050	1099	44	fs	fs	PROPN
fnp-3050	1099	45	,	,	PUNCT
fnp-3050	1099	46	knopman	knopman	NOUN
fnp-3050	1099	47	ds	ds	PROPN
fnp-3050	1099	48	,	,	PUNCT
fnp-3050	1099	49	jack	jack	PROPN
fnp-3050	1099	50	cr	cr	PROPN
fnp-3050	1099	51	,	,	PUNCT
fnp-3050	1099	52	jr	jr	PROPN
fnp-3050	1099	53	.	.	PROPN
fnp-3050	1099	54	,	,	PUNCT
fnp-3050	1099	55	dickson	dickson	PROPN
fnp-3050	1099	56	dw	dw	PROPN
fnp-3050	1099	57	,	,	PUNCT
fnp-3050	1099	58	petersen	petersen	PROPN
fnp-3050	1099	59	rc	rc	PROPN
fnp-3050	1099	60	,	,	PUNCT
fnp-3050	1099	61	murray	murray	VERB
fnp-3050	1099	62	me	i	PRON
fnp-3050	1099	63	(	(	PUNCT
fnp-3050	1099	64	2020	2020	NUM
fnp-3050	1099	65	)	)	PUNCT
fnp-3050	1099	66	tau	tau	NOUN
fnp-3050	1099	67	-	-	PUNCT
fnp-3050	1099	68	positron	positron	NOUN
fnp-3050	1099	69	emission	emission	NOUN
fnp-3050	1099	70	tomography	tomography	NOUN
fnp-3050	1099	71	correlates	correlate	VERB
fnp-3050	1099	72	with	with	ADP
fnp-3050	1099	73	neuropathology	neuropathology	NOUN
fnp-3050	1099	74	findings	finding	NOUN
fnp-3050	1099	75	.	.	PUNCT
fnp-3050	1100	1	alzheimers	alzheimers	PROPN
fnp-3050	1100	2	dement	dement	PROPN
fnp-3050	1100	3	16:561	16:561	PROPN
fnp-3050	1100	4	-	-	SYM
fnp-3050	1100	5	571	571	NUM
fnp-3050	1100	6	280	280	NUM
fnp-3050	1100	7	.	.	PUNCT
fnp-3050	1101	1	galton	galton	PROPN
fnp-3050	1101	2	cj	cj	PROPN
fnp-3050	1101	3	,	,	PUNCT
fnp-3050	1101	4	patterson	patterson	PROPN
fnp-3050	1101	5	k	k	PROPN
fnp-3050	1101	6	,	,	PUNCT
fnp-3050	1101	7	xuereb	xuereb	PROPN
fnp-3050	1101	8	jh	jh	PROPN
fnp-3050	1101	9	,	,	PUNCT
fnp-3050	1101	10	hodges	hodges	PROPN
fnp-3050	1101	11	jr	jr	PROPN
fnp-3050	1101	12	(	(	PUNCT
fnp-3050	1101	13	2000	2000	NUM
fnp-3050	1101	14	)	)	PUNCT
fnp-3050	1101	15	atypical	atypical	ADJ
fnp-3050	1101	16	and	and	CCONJ
fnp-3050	1101	17	typical	typical	ADJ
fnp-3050	1101	18	presentations	presentation	NOUN
fnp-3050	1101	19	of	of	ADP
fnp-3050	1101	20	alzheimer	alzheimer	PROPN
fnp-3050	1101	21	's	's	PART
fnp-3050	1101	22	disease	disease	NOUN
fnp-3050	1101	23	:	:	PUNCT
fnp-3050	1101	24	a	a	DET
fnp-3050	1101	25	clinical	clinical	ADJ
fnp-3050	1101	26	,	,	PUNCT
fnp-3050	1101	27	neuropsychological	neuropsychological	ADJ
fnp-3050	1101	28	,	,	PUNCT
fnp-3050	1101	29	neuroimaging	neuroimaging	ADJ
fnp-3050	1101	30	and	and	CCONJ
fnp-3050	1101	31	pathological	pathological	ADJ
fnp-3050	1101	32	study	study	NOUN
fnp-3050	1101	33	of	of	ADP
fnp-3050	1101	34	13	13	NUM
fnp-3050	1101	35	cases	case	NOUN
fnp-3050	1101	36	.	.	PUNCT
fnp-3050	1102	1	brain	brain	NOUN
fnp-3050	1102	2	123	123	NUM
fnp-3050	1102	3	pt	pt	NOUN
fnp-3050	1102	4	3:484	3:484	NOUN
fnp-3050	1102	5	-	-	SYM
fnp-3050	1102	6	498	498	NUM
fnp-3050	1102	7	281	281	NUM
fnp-3050	1102	8	.	.	PUNCT
fnp-3050	1103	1	lam	lam	PROPN
fnp-3050	1103	2	b	b	PROPN
fnp-3050	1103	3	,	,	PUNCT
fnp-3050	1103	4	masellis	masellis	PROPN
fnp-3050	1103	5	m	m	PROPN
fnp-3050	1103	6	,	,	PUNCT
fnp-3050	1103	7	freedman	freedman	PROPN
fnp-3050	1103	8	m	m	PROPN
fnp-3050	1103	9	,	,	PUNCT
fnp-3050	1103	10	stuss	stuss	ADJ
fnp-3050	1103	11	dt	dt	NOUN
fnp-3050	1103	12	,	,	PUNCT
fnp-3050	1103	13	black	black	ADJ
fnp-3050	1103	14	se	se	PROPN
fnp-3050	1103	15	(	(	PUNCT
fnp-3050	1103	16	2013	2013	NUM
fnp-3050	1103	17	)	)	PUNCT
fnp-3050	1103	18	clinical	clinical	ADJ
fnp-3050	1103	19	,	,	PUNCT
fnp-3050	1103	20	imaging	imaging	NOUN
fnp-3050	1103	21	,	,	PUNCT
fnp-3050	1103	22	and	and	CCONJ
fnp-3050	1103	23	pathological	pathological	ADJ
fnp-3050	1103	24	heterogeneity	heterogeneity	NOUN
fnp-3050	1103	25	of	of	ADP
fnp-3050	1103	26	the	the	DET
fnp-3050	1103	27	alzheimer	alzheimer	PROPN
fnp-3050	1103	28	's	's	PART
fnp-3050	1103	29	disease	disease	NOUN
fnp-3050	1103	30	syndrome	syndrome	NOUN
fnp-3050	1103	31	.	.	PUNCT
fnp-3050	1104	1	alzheimers	alzheimer	NOUN
fnp-3050	1104	2	res	re	VERB
fnp-3050	1104	3	ther	ther	ADV
fnp-3050	1104	4	5:1	5:1	NUM
fnp-3050	1104	5	282	282	NUM
fnp-3050	1104	6	.	.	PUNCT
fnp-3050	1105	1	ahmed	ahmed	PROPN
fnp-3050	1105	2	s	s	PROPN
fnp-3050	1105	3	,	,	PUNCT
fnp-3050	1105	4	de	de	X
fnp-3050	1105	5	jager	jager	PROPN
fnp-3050	1105	6	ca	can	AUX
fnp-3050	1105	7	,	,	PUNCT
fnp-3050	1105	8	haigh	haigh	PROPN
fnp-3050	1105	9	am	am	NOUN
fnp-3050	1105	10	,	,	PUNCT
fnp-3050	1105	11	garrard	garrard	PROPN
fnp-3050	1105	12	p	p	X
fnp-3050	1105	13	(	(	PUNCT
fnp-3050	1105	14	2012	2012	NUM
fnp-3050	1105	15	)	)	PUNCT
fnp-3050	1105	16	logopenic	logopenic	ADJ
fnp-3050	1105	17	aphasia	aphasia	NOUN
fnp-3050	1105	18	in	in	ADP
fnp-3050	1105	19	alzheimer	alzheimer	PROPN
fnp-3050	1105	20	's	's	PART
fnp-3050	1105	21	disease	disease	NOUN
fnp-3050	1105	22	:	:	PUNCT
fnp-3050	1105	23	clinical	clinical	ADJ
fnp-3050	1105	24	variant	variant	NOUN
fnp-3050	1105	25	or	or	CCONJ
fnp-3050	1105	26	clinical	clinical	ADJ
fnp-3050	1105	27	feature	feature	NOUN
fnp-3050	1105	28	?	?	PUNCT
fnp-3050	1106	1	j	j	PROPN
fnp-3050	1106	2	neurol	neurol	PROPN
fnp-3050	1106	3	neurosurg	neurosurg	PROPN
fnp-3050	1106	4	psychiatry	psychiatry	PROPN
fnp-3050	1106	5	83:1056	83:1056	NOUN
fnp-3050	1106	6	-	-	SYM
fnp-3050	1106	7	1062	1062	NUM
fnp-3050	1106	8	283	283	NUM
fnp-3050	1106	9	.	.	PUNCT
fnp-3050	1107	1	gorno	gorno	NOUN
fnp-3050	1107	2	-	-	PUNCT
fnp-3050	1107	3	tempini	tempini	PROPN
fnp-3050	1107	4	ml	ml	NOUN
fnp-3050	1107	5	,	,	PUNCT
fnp-3050	1107	6	brambati	brambati	PROPN
fnp-3050	1107	7	sm	sm	PROPN
fnp-3050	1107	8	,	,	PUNCT
fnp-3050	1107	9	ginex	ginex	PROPN
fnp-3050	1107	10	v	v	PROPN
fnp-3050	1107	11	,	,	PUNCT
fnp-3050	1107	12	ogar	ogar	PROPN
fnp-3050	1107	13	j	j	PROPN
fnp-3050	1107	14	,	,	PUNCT
fnp-3050	1107	15	dronkers	dronker	NOUN
fnp-3050	1107	16	nf	nf	ADP
fnp-3050	1107	17	,	,	PUNCT
fnp-3050	1107	18	marcone	marcone	NOUN
fnp-3050	1107	19	a	a	PRON
fnp-3050	1107	20	,	,	PUNCT
fnp-3050	1107	21	perani	perani	PROPN
fnp-3050	1107	22	d	d	NOUN
fnp-3050	1107	23	,	,	PUNCT
fnp-3050	1107	24	garibotto	garibotto	NOUN
fnp-3050	1107	25	v	v	NOUN
fnp-3050	1107	26	,	,	PUNCT
fnp-3050	1107	27	cappa	cappa	PROPN
fnp-3050	1107	28	sf	sf	PROPN
fnp-3050	1107	29	,	,	PUNCT
fnp-3050	1107	30	miller	miller	PROPN
fnp-3050	1107	31	bl	bl	PROPN
fnp-3050	1107	32	(	(	PUNCT
fnp-3050	1107	33	2008	2008	NUM
fnp-3050	1107	34	)	)	PUNCT
fnp-3050	1107	35	the	the	DET
fnp-3050	1107	36	logopenic	logopenic	ADJ
fnp-3050	1107	37	/	/	SYM
fnp-3050	1107	38	phonological	phonological	ADJ
fnp-3050	1107	39	variant	variant	NOUN
fnp-3050	1107	40	of	of	ADP
fnp-3050	1107	41	primary	primary	ADJ
fnp-3050	1107	42	progressive	progressive	ADJ
fnp-3050	1107	43	aphasia	aphasia	NOUN
fnp-3050	1107	44	.	.	PUNCT
fnp-3050	1108	1	neurology	neurology	NOUN
fnp-3050	1108	2	71:1227	71:1227	NOUN
fnp-3050	1108	3	-	-	SYM
fnp-3050	1108	4	1234	1234	NUM
fnp-3050	1108	5	284	284	NUM
fnp-3050	1108	6	.	.	PUNCT
fnp-3050	1109	1	spinelli	spinelli	PROPN
fnp-3050	1109	2	eg	eg	PROPN
fnp-3050	1109	3	,	,	PUNCT
fnp-3050	1109	4	mandelli	mandelli	PROPN
fnp-3050	1109	5	ml	ml	PROPN
fnp-3050	1109	6	,	,	PUNCT
fnp-3050	1109	7	miller	miller	PROPN
fnp-3050	1109	8	za	za	PROPN
fnp-3050	1109	9	,	,	PUNCT
fnp-3050	1109	10	santos	santos	PROPN
fnp-3050	1109	11	-	-	PUNCT
fnp-3050	1109	12	santos	santos	PROPN
fnp-3050	1109	13	ma	ma	PROPN
fnp-3050	1109	14	,	,	PUNCT
fnp-3050	1109	15	wilson	wilson	PROPN
fnp-3050	1109	16	sm	sm	PROPN
fnp-3050	1109	17	,	,	PUNCT
fnp-3050	1109	18	agosta	agosta	ADJ
fnp-3050	1109	19	f	f	PROPN
fnp-3050	1109	20	,	,	PUNCT
fnp-3050	1109	21	grinberg	grinberg	PROPN
fnp-3050	1109	22	lt	lt	PROPN
fnp-3050	1109	23	,	,	PUNCT
fnp-3050	1109	24	huang	huang	PROPN
fnp-3050	1109	25	ej	ej	PROPN
fnp-3050	1109	26	,	,	PUNCT
fnp-3050	1109	27	trojanowski	trojanowski	PROPN
fnp-3050	1109	28	jq	jq	PROPN
fnp-3050	1109	29	,	,	PUNCT
fnp-3050	1109	30	meyer	meyer	PROPN
fnp-3050	1109	31	m	m	PROPN
fnp-3050	1109	32	,	,	PUNCT
fnp-3050	1109	33	henry	henry	PROPN
fnp-3050	1109	34	ml	ml	PROPN
fnp-3050	1109	35	,	,	PUNCT
fnp-3050	1109	36	comi	comi	NOUN
fnp-3050	1109	37	g	g	NOUN
fnp-3050	1109	38	,	,	PUNCT
fnp-3050	1109	39	rabinovici	rabinovici	NOUN
fnp-3050	1109	40	g	g	PROPN
fnp-3050	1109	41	,	,	PUNCT
fnp-3050	1109	42	rosen	rosen	PROPN
fnp-3050	1109	43	hj	hj	PROPN
fnp-3050	1109	44	,	,	PUNCT
fnp-3050	1109	45	filippi	filippi	PROPN
fnp-3050	1109	46	m	m	PROPN
fnp-3050	1109	47	,	,	PUNCT
fnp-3050	1109	48	miller	miller	PROPN
fnp-3050	1109	49	bl	bl	PROPN
fnp-3050	1109	50	,	,	PUNCT
fnp-3050	1109	51	seeley	seeley	PROPN
fnp-3050	1109	52	ww	ww	PROPN
fnp-3050	1109	53	,	,	PUNCT
fnp-3050	1109	54	gorno	gorno	NOUN
fnp-3050	1109	55	-	-	PUNCT
fnp-3050	1109	56	tempini	tempini	PROPN
fnp-3050	1109	57	ml	ml	X
fnp-3050	1109	58	(	(	PUNCT
fnp-3050	1109	59	2017	2017	NUM
fnp-3050	1109	60	)	)	PUNCT
fnp-3050	1109	61	typical	typical	ADJ
fnp-3050	1109	62	and	and	CCONJ
fnp-3050	1109	63	atypical	atypical	ADJ
fnp-3050	1109	64	pathology	pathology	NOUN
fnp-3050	1109	65	in	in	ADP
fnp-3050	1109	66	primary	primary	ADJ
fnp-3050	1109	67	progressive	progressive	ADJ
fnp-3050	1109	68	aphasia	aphasia	NOUN
fnp-3050	1109	69	variants	variant	NOUN
fnp-3050	1109	70	.	.	PUNCT
fnp-3050	1110	1	ann	ann	PROPN
fnp-3050	1110	2	neurol	neurol	PROPN
fnp-3050	1110	3	81:430	81:430	PROPN
fnp-3050	1110	4	-	-	SYM
fnp-3050	1110	5	443	443	NUM
fnp-3050	1110	6	285	285	NUM
fnp-3050	1110	7	.	.	PUNCT
fnp-3050	1111	1	weintraub	weintraub	PROPN
fnp-3050	1111	2	s	s	PROPN
fnp-3050	1111	3	,	,	PUNCT
fnp-3050	1111	4	teylan	teylan	NOUN
fnp-3050	1111	5	m	m	PROPN
fnp-3050	1111	6	,	,	PUNCT
fnp-3050	1111	7	rader	rader	PROPN
fnp-3050	1111	8	b	b	PROPN
fnp-3050	1111	9	,	,	PUNCT
fnp-3050	1111	10	chan	chan	PROPN
fnp-3050	1111	11	kcg	kcg	PROPN
fnp-3050	1111	12	,	,	PUNCT
fnp-3050	1111	13	bollenbeck	bollenbeck	PROPN
fnp-3050	1111	14	m	m	PROPN
fnp-3050	1111	15	,	,	PUNCT
fnp-3050	1111	16	kukull	kukull	PROPN
fnp-3050	1111	17	wa	wa	PROPN
fnp-3050	1111	18	,	,	PUNCT
fnp-3050	1111	19	coventry	coventry	PROPN
fnp-3050	1111	20	c	c	PROPN
fnp-3050	1111	21	,	,	PUNCT
fnp-3050	1111	22	rogalski	rogalski	NOUN
fnp-3050	1111	23	e	e	PROPN
fnp-3050	1111	24	,	,	PUNCT
fnp-3050	1111	25	bigio	bigio	NOUN
fnp-3050	1111	26	e	e	NOUN
fnp-3050	1111	27	,	,	PUNCT
fnp-3050	1111	28	mesulam	mesulam	PROPN
fnp-3050	1111	29	mm	mm	PROPN
fnp-3050	1111	30	(	(	PUNCT
fnp-3050	1111	31	2020	2020	NUM
fnp-3050	1111	32	)	)	PUNCT
fnp-3050	1112	1	apoe	apoe	NOUN
fnp-3050	1112	2	is	be	AUX
fnp-3050	1112	3	a	a	DET
fnp-3050	1112	4	correlate	correlate	NOUN
fnp-3050	1112	5	of	of	ADP
fnp-3050	1112	6	phenotypic	phenotypic	ADJ
fnp-3050	1112	7	heterogeneity	heterogeneity	NOUN
fnp-3050	1112	8	in	in	ADP
fnp-3050	1112	9	alzheimer	alzheimer	PROPN
fnp-3050	1112	10	disease	disease	NOUN
fnp-3050	1112	11	in	in	ADP
fnp-3050	1112	12	a	a	DET
fnp-3050	1112	13	national	national	ADJ
fnp-3050	1112	14	cohort	cohort	NOUN
fnp-3050	1112	15	.	.	PUNCT
fnp-3050	1113	1	neurology	neurology	NOUN
fnp-3050	1113	2	94	94	NUM
fnp-3050	1113	3	:	:	PUNCT
fnp-3050	1113	4	e607	e607	PROPN
fnp-3050	1113	5	-	-	PUNCT
fnp-3050	1113	6	e612	e612	PROPN
fnp-3050	1113	7	286	286	NUM
fnp-3050	1113	8	.	.	PUNCT
fnp-3050	1114	1	crutch	crutch	NOUN
fnp-3050	1114	2	sj	sj	PROPN
fnp-3050	1114	3	,	,	PUNCT
fnp-3050	1114	4	schott	schott	PROPN
fnp-3050	1114	5	jm	jm	PROPN
fnp-3050	1114	6	,	,	PUNCT
fnp-3050	1114	7	rabinovici	rabinovici	PROPN
fnp-3050	1114	8	gd	gd	PROPN
fnp-3050	1114	9	,	,	PUNCT
fnp-3050	1114	10	murray	murray	PROPN
fnp-3050	1114	11	m	m	PROPN
fnp-3050	1114	12	,	,	PUNCT
fnp-3050	1114	13	snowden	snowden	PROPN
fnp-3050	1114	14	js	js	PROPN
fnp-3050	1114	15	,	,	PUNCT
fnp-3050	1114	16	van	van	PROPN
fnp-3050	1114	17	der	der	PROPN
fnp-3050	1114	18	flier	flier	PROPN
fnp-3050	1114	19	wm	wm	PROPN
fnp-3050	1114	20	,	,	PUNCT
fnp-3050	1114	21	dickerson	dickerson	PROPN
fnp-3050	1114	22	bc	bc	PROPN
fnp-3050	1114	23	,	,	PUNCT
fnp-3050	1114	24	vandenberghe	vandenberghe	PROPN
fnp-3050	1114	25	r	r	PROPN
fnp-3050	1114	26	,	,	PUNCT
fnp-3050	1114	27	ahmed	ahmed	PROPN
fnp-3050	1114	28	s	s	PROPN
fnp-3050	1114	29	,	,	PUNCT
fnp-3050	1114	30	bak	bak	X
fnp-3050	1114	31	th	th	NUM
fnp-3050	1114	32	,	,	PUNCT
fnp-3050	1114	33	boeve	boeve	NOUN
fnp-3050	1114	34	bf	bf	PROPN
fnp-3050	1114	35	,	,	PUNCT
fnp-3050	1114	36	butler	butler	PROPN
fnp-3050	1114	37	c	c	PROPN
fnp-3050	1114	38	,	,	PUNCT
fnp-3050	1114	39	cappa	cappa	PROPN
fnp-3050	1114	40	sf	sf	PROPN
fnp-3050	1114	41	,	,	PUNCT
fnp-3050	1114	42	ceccaldi	ceccaldi	PROPN
fnp-3050	1114	43	m	m	PROPN
fnp-3050	1114	44	,	,	PUNCT
fnp-3050	1114	45	de	de	PROPN
fnp-3050	1114	46	souza	souza	PROPN
fnp-3050	1114	47	lc	lc	PROPN
fnp-3050	1114	48	,	,	PUNCT
fnp-3050	1114	49	dubois	dubois	PROPN
fnp-3050	1114	50	b	b	PROPN
fnp-3050	1114	51	,	,	PUNCT
fnp-3050	1114	52	felician	felician	ADJ
fnp-3050	1114	53	o	o	NOUN
fnp-3050	1114	54	,	,	PUNCT
fnp-3050	1114	55	galasko	galasko	PROPN
fnp-3050	1114	56	d	d	PROPN
fnp-3050	1114	57	,	,	PUNCT
fnp-3050	1114	58	graff	graff	NOUN
fnp-3050	1114	59	-	-	PUNCT
fnp-3050	1114	60	radford	radford	PROPN
fnp-3050	1114	61	j	j	PROPN
fnp-3050	1114	62	,	,	PUNCT
fnp-3050	1114	63	graff	graff	PROPN
fnp-3050	1114	64	-	-	PUNCT
fnp-3050	1114	65	radford	radford	PROPN
fnp-3050	1114	66	nr	nr	PROPN
fnp-3050	1114	67	,	,	PUNCT
fnp-3050	1114	68	hof	hof	PROPN
fnp-3050	1114	69	pr	pr	NOUN
fnp-3050	1114	70	,	,	PUNCT
fnp-3050	1114	71	krolak	krolak	ADJ
fnp-3050	1114	72	-	-	PUNCT
fnp-3050	1114	73	salmon	salmon	NOUN
fnp-3050	1114	74	p	p	NOUN
fnp-3050	1114	75	,	,	PUNCT
fnp-3050	1114	76	lehmann	lehmann	PROPN
fnp-3050	1114	77	m	m	PROPN
fnp-3050	1114	78	,	,	PUNCT
fnp-3050	1114	79	magnin	magnin	PROPN
fnp-3050	1114	80	e	e	NOUN
fnp-3050	1114	81	,	,	PUNCT
fnp-3050	1114	82	mendez	mendez	PROPN
fnp-3050	1114	83	mf	mf	PROPN
fnp-3050	1114	84	,	,	PUNCT
fnp-3050	1114	85	nestor	nestor	PROPN
fnp-3050	1114	86	pj	pj	PROPN
fnp-3050	1114	87	,	,	PUNCT
fnp-3050	1114	88	onyike	onyike	PROPN
fnp-3050	1114	89	cu	cu	PROPN
fnp-3050	1114	90	,	,	PUNCT
fnp-3050	1114	91	pelak	pelak	NOUN
fnp-3050	1114	92	vs	vs	ADP
fnp-3050	1114	93	,	,	PUNCT
fnp-3050	1114	94	pijnenburg	pijnenburg	PROPN
fnp-3050	1114	95	y	y	PROPN
fnp-3050	1114	96	,	,	PUNCT
fnp-3050	1114	97	primativo	primativo	VERB
fnp-3050	1114	98	s	s	PROPN
fnp-3050	1114	99	,	,	PUNCT
fnp-3050	1114	100	rossor	rossor	PROPN
fnp-3050	1114	101	mn	mn	PROPN
fnp-3050	1114	102	,	,	PUNCT
fnp-3050	1114	103	ryan	ryan	PROPN
fnp-3050	1114	104	ns	ns	PROPN
fnp-3050	1114	105	,	,	PUNCT
fnp-3050	1114	106	scheltens	schelten	VERB
fnp-3050	1114	107	p	p	NOUN
fnp-3050	1114	108	,	,	PUNCT
fnp-3050	1114	109	shakespeare	shakespeare	PROPN
fnp-3050	1114	110	tj	tj	PROPN
fnp-3050	1114	111	,	,	PUNCT
fnp-3050	1114	112	suarez	suarez	PROPN
fnp-3050	1114	113	gonzalez	gonzalez	PROPN
fnp-3050	1114	114	a	a	PRON
fnp-3050	1114	115	,	,	PUNCT
fnp-3050	1114	116	tang	tang	PROPN
fnp-3050	1114	117	-	-	PUNCT
fnp-3050	1114	118	wai	wai	PROPN
fnp-3050	1114	119	df	df	PROPN
fnp-3050	1114	120	,	,	PUNCT
fnp-3050	1114	121	yong	yong	PROPN
fnp-3050	1114	122	kxx	kxx	PROPN
fnp-3050	1114	123	,	,	PUNCT
fnp-3050	1114	124	carrillo	carrillo	PROPN
fnp-3050	1114	125	m	m	PROPN
fnp-3050	1114	126	,	,	PUNCT
fnp-3050	1114	127	fox	fox	PROPN
fnp-3050	1114	128	nc	nc	PROPN
fnp-3050	1114	129	(	(	PUNCT
fnp-3050	1114	130	2017	2017	NUM
fnp-3050	1114	131	)	)	PUNCT
fnp-3050	1114	132	consensus	consensus	NOUN
fnp-3050	1114	133	classification	classification	NOUN
fnp-3050	1114	134	of	of	ADP
fnp-3050	1114	135	posterior	posterior	ADJ
fnp-3050	1114	136	cortical	cortical	ADJ
fnp-3050	1114	137	atrophy	atrophy	NOUN
fnp-3050	1114	138	.	.	PUNCT
fnp-3050	1115	1	alzheimers	alzheimers	PROPN
fnp-3050	1115	2	dement	dement	PROPN
fnp-3050	1115	3	13:870	13:870	PROPN
fnp-3050	1115	4	-	-	SYM
fnp-3050	1115	5	884	884	NUM
fnp-3050	1115	6	287	287	NUM
fnp-3050	1115	7	.	.	PUNCT
fnp-3050	1116	1	sahoo	sahoo	PROPN
fnp-3050	1116	2	a	a	PROPN
fnp-3050	1116	3	,	,	PUNCT
fnp-3050	1116	4	bejanin	bejanin	PROPN
fnp-3050	1116	5	a	a	PRON
fnp-3050	1116	6	,	,	PUNCT
fnp-3050	1116	7	murray	murray	VERB
fnp-3050	1116	8	me	i	PRON
fnp-3050	1116	9	,	,	PUNCT
fnp-3050	1116	10	tosakulwong	tosakulwong	ADP
fnp-3050	1116	11	n	n	CCONJ
fnp-3050	1116	12	,	,	PUNCT
fnp-3050	1116	13	weigand	weigand	NOUN
fnp-3050	1116	14	sd	sd	NOUN
fnp-3050	1116	15	,	,	PUNCT
fnp-3050	1116	16	serie	serie	PROPN
fnp-3050	1116	17	am	be	AUX
fnp-3050	1116	18	,	,	PUNCT
fnp-3050	1116	19	senjem	senjem	VERB
fnp-3050	1116	20	ml	ml	ADP
fnp-3050	1116	21	,	,	PUNCT
fnp-3050	1116	22	machulda	machulda	PROPN
fnp-3050	1116	23	mm	mm	PROPN
fnp-3050	1116	24	,	,	PUNCT
fnp-3050	1116	25	parisi	parisi	PROPN
fnp-3050	1116	26	je	je	PROPN
fnp-3050	1116	27	,	,	PUNCT
fnp-3050	1116	28	boeve	boeve	PROPN
fnp-3050	1116	29	bf	bf	NOUN
fnp-3050	1116	30	,	,	PUNCT
fnp-3050	1116	31	knopman	knopman	NOUN
fnp-3050	1116	32	ds	ds	PROPN
fnp-3050	1116	33	,	,	PUNCT
fnp-3050	1116	34	petersen	petersen	PROPN
fnp-3050	1116	35	rc	rc	PROPN
fnp-3050	1116	36	,	,	PUNCT
fnp-3050	1116	37	dickson	dickson	PROPN
fnp-3050	1116	38	dw	dw	PROPN
fnp-3050	1116	39	,	,	PUNCT
fnp-3050	1116	40	whitwell	whitwell	PROPN
fnp-3050	1116	41	jl	jl	PROPN
fnp-3050	1116	42	,	,	PUNCT
fnp-3050	1116	43	josephs	josephs	PROPN
fnp-3050	1116	44	ka	ka	PROPN
fnp-3050	1116	45	(	(	PUNCT
fnp-3050	1116	46	2018	2018	NUM
fnp-3050	1116	47	)	)	PUNCT
fnp-3050	1116	48	tdp-43	tdp-43	PROPN
fnp-3050	1116	49	and	and	CCONJ
fnp-3050	1116	50	alzheimer	alzheimer	PROPN
fnp-3050	1116	51	's	's	PART
fnp-3050	1116	52	disease	disease	NOUN
fnp-3050	1116	53	pathologic	pathologic	ADJ
fnp-3050	1116	54	subtype	subtype	NOUN
fnp-3050	1116	55	in	in	ADP
fnp-3050	1116	56	non	non	ADJ
fnp-3050	1116	57	-	-	ADJ
fnp-3050	1116	58	amnestic	amnestic	ADJ
fnp-3050	1116	59	alzheimer	alzheimer	PROPN
fnp-3050	1116	60	's	's	PART
fnp-3050	1116	61	disease	disease	NOUN
fnp-3050	1116	62	dementia	dementia	NOUN
fnp-3050	1116	63	.	.	PUNCT
fnp-3050	1117	1	j	j	PROPN
fnp-3050	1117	2	alzheimers	alzheimers	PROPN
fnp-3050	1117	3	dis	dis	PROPN
fnp-3050	1117	4	64:1227	64:1227	NOUN
fnp-3050	1117	5	-	-	SYM
fnp-3050	1117	6	1233	1233	NUM
fnp-3050	1117	7	288	288	NUM
fnp-3050	1117	8	.	.	PUNCT
fnp-3050	1118	1	rascovsky	rascovsky	PROPN
fnp-3050	1118	2	k	k	PROPN
fnp-3050	1118	3	,	,	PUNCT
fnp-3050	1118	4	hodges	hodges	PROPN
fnp-3050	1118	5	jr	jr	PROPN
fnp-3050	1118	6	,	,	PUNCT
fnp-3050	1118	7	knopman	knopman	NOUN
fnp-3050	1118	8	d	d	PROPN
fnp-3050	1118	9	,	,	PUNCT
fnp-3050	1118	10	mendez	mendez	PROPN
fnp-3050	1118	11	mf	mf	PROPN
fnp-3050	1118	12	,	,	PUNCT
fnp-3050	1118	13	kramer	kramer	PROPN
fnp-3050	1118	14	jh	jh	PROPN
fnp-3050	1118	15	,	,	PUNCT
fnp-3050	1118	16	neuhaus	neuhaus	PROPN
fnp-3050	1118	17	j	j	PROPN
fnp-3050	1118	18	,	,	PUNCT
fnp-3050	1118	19	van	van	PROPN
fnp-3050	1118	20	swieten	swieten	PROPN
fnp-3050	1118	21	jc	jc	PROPN
fnp-3050	1118	22	,	,	PUNCT
fnp-3050	1118	23	seelaar	seelaar	NOUN
fnp-3050	1118	24	h	h	PROPN
fnp-3050	1118	25	,	,	PUNCT
fnp-3050	1118	26	dopper	dopper	ADJ
fnp-3050	1118	27	eg	eg	NOUN
fnp-3050	1118	28	,	,	PUNCT
fnp-3050	1118	29	onyike	onyike	PROPN
fnp-3050	1118	30	cu	cu	PROPN
fnp-3050	1118	31	,	,	PUNCT
fnp-3050	1118	32	hillis	hillis	PROPN
fnp-3050	1118	33	ae	ae	PROPN
fnp-3050	1118	34	,	,	PUNCT
fnp-3050	1118	35	josephs	josephs	PROPN
fnp-3050	1118	36	ka	ka	PROPN
fnp-3050	1118	37	,	,	PUNCT
fnp-3050	1118	38	boeve	boeve	NOUN
fnp-3050	1118	39	bf	bf	NOUN
fnp-3050	1118	40	,	,	PUNCT
fnp-3050	1118	41	kertesz	kertesz	NOUN
fnp-3050	1118	42	a	a	PROPN
fnp-3050	1118	43	,	,	PUNCT
fnp-3050	1118	44	seeley	seeley	PROPN
fnp-3050	1118	45	ww	ww	PROPN
fnp-3050	1118	46	,	,	PUNCT
fnp-3050	1118	47	rankin	rankin	PROPN
fnp-3050	1118	48	kp	kp	PROPN
fnp-3050	1118	49	,	,	PUNCT
fnp-3050	1118	50	johnson	johnson	PROPN
fnp-3050	1118	51	jk	jk	PROPN
fnp-3050	1118	52	,	,	PUNCT
fnp-3050	1118	53	gorno	gorno	PROPN
fnp-3050	1118	54	-	-	PUNCT
fnp-3050	1118	55	tempini	tempini	PROPN
fnp-3050	1118	56	ml	ml	PROPN
fnp-3050	1118	57	,	,	PUNCT
fnp-3050	1118	58	rosen	rosen	PROPN
fnp-3050	1118	59	h	h	PROPN
fnp-3050	1118	60	,	,	PUNCT
fnp-3050	1118	61	prioleau	prioleau	PROPN
fnp-3050	1118	62	-	-	PUNCT
fnp-3050	1118	63	latham	latham	PROPN
fnp-3050	1118	64	ce	ce	PROPN
fnp-3050	1118	65	,	,	PUNCT
fnp-3050	1118	66	lee	lee	PROPN
fnp-3050	1118	67	a	a	PROPN
fnp-3050	1118	68	,	,	PUNCT
fnp-3050	1118	69	kipps	kipps	PROPN
fnp-3050	1118	70	cm	cm	PROPN
fnp-3050	1118	71	,	,	PUNCT
fnp-3050	1118	72	lillo	lillo	PROPN
fnp-3050	1118	73	p	p	NOUN
fnp-3050	1118	74	,	,	PUNCT
fnp-3050	1118	75	piguet	piguet	PROPN
fnp-3050	1118	76	o	o	NOUN
fnp-3050	1118	77	,	,	PUNCT
fnp-3050	1118	78	rohrer	rohrer	PROPN
fnp-3050	1118	79	jd	jd	PROPN
fnp-3050	1118	80	,	,	PUNCT
fnp-3050	1118	81	rossor	rossor	PROPN
fnp-3050	1118	82	mn	mn	PROPN
fnp-3050	1118	83	,	,	PUNCT
fnp-3050	1118	84	warren	warren	PROPN
fnp-3050	1118	85	jd	jd	PROPN
fnp-3050	1118	86	,	,	PUNCT
fnp-3050	1118	87	fox	fox	PROPN
fnp-3050	1118	88	nc	nc	PROPN
fnp-3050	1118	89	,	,	PUNCT
fnp-3050	1118	90	galasko	galasko	PROPN
fnp-3050	1118	91	d	d	PROPN
fnp-3050	1118	92	,	,	PUNCT
fnp-3050	1118	93	salmon	salmon	NOUN
fnp-3050	1118	94	dp	dp	NOUN
fnp-3050	1118	95	,	,	PUNCT
fnp-3050	1118	96	black	black	ADJ
fnp-3050	1118	97	se	se	X
fnp-3050	1118	98	,	,	PUNCT
fnp-3050	1118	99	mesulam	mesulam	PROPN
fnp-3050	1118	100	m	m	PROPN
fnp-3050	1118	101	,	,	PUNCT
fnp-3050	1118	102	weintraub	weintraub	PROPN
fnp-3050	1118	103	s	s	PROPN
fnp-3050	1118	104	,	,	PUNCT
fnp-3050	1118	105	dickerson	dickerson	PROPN
fnp-3050	1118	106	bc	bc	PROPN
fnp-3050	1118	107	,	,	PUNCT
fnp-3050	1118	108	diehl	diehl	PROPN
fnp-3050	1118	109	-	-	PUNCT
fnp-3050	1118	110	schmid	schmid	PROPN
fnp-3050	1118	111	j	j	PROPN
fnp-3050	1118	112	,	,	PUNCT
fnp-3050	1118	113	pasquier	pasquier	NOUN
fnp-3050	1118	114	f	f	PROPN
fnp-3050	1118	115	,	,	PUNCT
fnp-3050	1118	116	deramecourt	deramecourt	NOUN
fnp-3050	1118	117	v	v	ADP
fnp-3050	1118	118	,	,	PUNCT
fnp-3050	1118	119	lebert	lebert	PROPN
fnp-3050	1118	120	f	f	PROPN
fnp-3050	1118	121	,	,	PUNCT
fnp-3050	1118	122	pijnenburg	pijnenburg	PROPN
fnp-3050	1118	123	y	y	PROPN
fnp-3050	1118	124	,	,	PUNCT
fnp-3050	1118	125	chow	chow	PROPN
fnp-3050	1118	126	tw	tw	NOUN
fnp-3050	1118	127	,	,	PUNCT
fnp-3050	1118	128	manes	mane	NOUN
fnp-3050	1118	129	f	f	PROPN
fnp-3050	1118	130	,	,	PUNCT
fnp-3050	1118	131	grafman	grafman	PROPN
fnp-3050	1118	132	j	j	PROPN
fnp-3050	1118	133	,	,	PUNCT
fnp-3050	1118	134	cappa	cappa	PROPN
fnp-3050	1118	135	sf	sf	PROPN
fnp-3050	1118	136	,	,	PUNCT
fnp-3050	1118	137	freedman	freedman	PROPN
fnp-3050	1118	138	m	m	PROPN
fnp-3050	1118	139	,	,	PUNCT
fnp-3050	1118	140	grossman	grossman	PROPN
fnp-3050	1118	141	m	m	PROPN
fnp-3050	1118	142	,	,	PUNCT
fnp-3050	1118	143	miller	miller	PROPN
fnp-3050	1118	144	bl	bl	PROPN
fnp-3050	1118	145	(	(	PUNCT
fnp-3050	1118	146	2011	2011	NUM
fnp-3050	1118	147	)	)	PUNCT
fnp-3050	1118	148	sensitivity	sensitivity	NOUN
fnp-3050	1118	149	of	of	ADP
fnp-3050	1118	150	revised	revise	VERB
fnp-3050	1118	151	diagnostic	diagnostic	ADJ
fnp-3050	1118	152	criteria	criterion	NOUN
fnp-3050	1118	153	for	for	ADP
fnp-3050	1118	154	the	the	DET
fnp-3050	1118	155	behavioural	behavioural	ADJ
fnp-3050	1118	156	variant	variant	NOUN
fnp-3050	1118	157	of	of	ADP
fnp-3050	1118	158	frontotemporal	frontotemporal	ADJ
fnp-3050	1118	159	dementia	dementia	NOUN
fnp-3050	1118	160	.	.	PUNCT
fnp-3050	1119	1	brain	brain	NOUN
fnp-3050	1119	2	134:2456	134:2456	NUM
fnp-3050	1119	3	-	-	SYM
fnp-3050	1119	4	2477	2477	NUM
fnp-3050	1119	5	289	289	NUM
fnp-3050	1119	6	.	.	PUNCT
fnp-3050	1120	1	sakae	sakae	PROPN
fnp-3050	1120	2	n	n	PROPN
fnp-3050	1120	3	,	,	PUNCT
fnp-3050	1120	4	josephs	josephs	PROPN
fnp-3050	1120	5	ka	ka	PROPN
fnp-3050	1120	6	,	,	PUNCT
fnp-3050	1120	7	litvan	litvan	PROPN
fnp-3050	1120	8	i	i	PRON
fnp-3050	1120	9	,	,	PUNCT
fnp-3050	1120	10	murray	murray	VERB
fnp-3050	1120	11	me	i	PRON
fnp-3050	1120	12	,	,	PUNCT
fnp-3050	1120	13	duara	duara	PROPN
fnp-3050	1120	14	r	r	PROPN
fnp-3050	1120	15	,	,	PUNCT
fnp-3050	1120	16	uitti	uitti	PROPN
fnp-3050	1120	17	rj	rj	PROPN
fnp-3050	1120	18	,	,	PUNCT
fnp-3050	1120	19	wszolek	wszolek	VERB
fnp-3050	1120	20	zk	zk	PROPN
fnp-3050	1120	21	,	,	PUNCT
fnp-3050	1120	22	van	van	PROPN
fnp-3050	1120	23	gerpen	gerpen	PROPN
fnp-3050	1120	24	j	j	PROPN
fnp-3050	1120	25	,	,	PUNCT
fnp-3050	1120	26	graff	graff	PROPN
fnp-3050	1120	27	-	-	PUNCT
fnp-3050	1120	28	radford	radford	PROPN
fnp-3050	1120	29	nr	nr	PROPN
fnp-3050	1120	30	,	,	PUNCT
fnp-3050	1120	31	dickson	dickson	PROPN
fnp-3050	1120	32	dw	dw	PROPN
fnp-3050	1120	33	(	(	PUNCT
fnp-3050	1120	34	2019	2019	NUM
fnp-3050	1120	35	)	)	PUNCT
fnp-3050	1120	36	clinicopathologic	clinicopathologic	ADJ
fnp-3050	1120	37	subtype	subtype	NOUN
fnp-3050	1120	38	of	of	ADP
fnp-3050	1120	39	alzheimer	alzheimer	PROPN
fnp-3050	1120	40	's	's	PART
fnp-3050	1120	41	disease	disease	NOUN
fnp-3050	1120	42	presenting	present	VERB
fnp-3050	1120	43	as	as	ADP
fnp-3050	1120	44	corticobasal	corticobasal	NOUN
fnp-3050	1120	45	syndrome	syndrome	NOUN
fnp-3050	1120	46	.	.	PUNCT
fnp-3050	1121	1	alzheimers	alzheimers	PROPN
fnp-3050	1121	2	dement	dement	PROPN
fnp-3050	1121	3	15:1218	15:1218	PROPN
fnp-3050	1121	4	-	-	SYM
fnp-3050	1121	5	1228	1228	NUM
fnp-3050	1121	6	290	290	NUM
fnp-3050	1121	7	.	.	PUNCT
fnp-3050	1122	1	josephs	josephs	PROPN
fnp-3050	1122	2	ka	ka	PROPN
fnp-3050	1122	3	,	,	PUNCT
fnp-3050	1122	4	whitwell	whitwell	PROPN
fnp-3050	1122	5	jl	jl	NOUN
fnp-3050	1122	6	,	,	PUNCT
fnp-3050	1122	7	tosakulwong	tosakulwong	ADP
fnp-3050	1122	8	n	n	CCONJ
fnp-3050	1122	9	,	,	PUNCT
fnp-3050	1122	10	weigand	weigand	NOUN
fnp-3050	1122	11	sd	sd	PROPN
fnp-3050	1122	12	,	,	PUNCT
fnp-3050	1122	13	murray	murray	VERB
fnp-3050	1122	14	me	i	PRON
fnp-3050	1122	15	,	,	PUNCT
fnp-3050	1122	16	liesinger	liesinger	ADJ
fnp-3050	1122	17	am	be	AUX
fnp-3050	1122	18	,	,	PUNCT
fnp-3050	1122	19	petrucelli	petrucelli	ADJ
fnp-3050	1122	20	l	l	NOUN
fnp-3050	1122	21	,	,	PUNCT
fnp-3050	1122	22	senjem	senjem	NOUN
fnp-3050	1122	23	ml	ml	VERB
fnp-3050	1122	24	,	,	PUNCT
fnp-3050	1122	25	ivnik	ivnik	PROPN
fnp-3050	1122	26	rj	rj	PROPN
fnp-3050	1122	27	,	,	PUNCT
fnp-3050	1122	28	parisi	parisi	PROPN
fnp-3050	1122	29	je	je	PROPN
fnp-3050	1122	30	,	,	PUNCT
fnp-3050	1122	31	petersen	petersen	PROPN
fnp-3050	1122	32	rc	rc	PROPN
fnp-3050	1122	33	,	,	PUNCT
fnp-3050	1122	34	dickson	dickson	PROPN
fnp-3050	1122	35	dw	dw	PROPN
fnp-3050	1122	36	(	(	PUNCT
fnp-3050	1122	37	2015	2015	NUM
fnp-3050	1122	38	)	)	PUNCT
fnp-3050	1122	39	tar	tar	NOUN
fnp-3050	1122	40	dna	dna	NOUN
fnp-3050	1122	41	-	-	PUNCT
fnp-3050	1122	42	binding	bind	VERB
fnp-3050	1122	43	protein	protein	NOUN
fnp-3050	1122	44	43	43	NUM
fnp-3050	1122	45	and	and	CCONJ
fnp-3050	1122	46	pathological	pathological	ADJ
fnp-3050	1122	47	subtype	subtype	NOUN
fnp-3050	1122	48	of	of	ADP
fnp-3050	1122	49	alzheimer	alzheimer	PROPN
fnp-3050	1122	50	's	's	PART
fnp-3050	1122	51	disease	disease	NOUN
fnp-3050	1122	52	impact	impact	VERB
fnp-3050	1122	53	clinical	clinical	ADJ
fnp-3050	1122	54	features	feature	NOUN
fnp-3050	1122	55	.	.	PUNCT
fnp-3050	1123	1	ann	ann	PROPN
fnp-3050	1123	2	neurol	neurol	PROPN
fnp-3050	1123	3	78:697	78:697	NUM
fnp-3050	1123	4	-	-	SYM
fnp-3050	1123	5	709	709	NUM
fnp-3050	1123	6	291	291	NUM
fnp-3050	1123	7	.	.	PUNCT
fnp-3050	1123	8	ohm	ohm	PROPN
fnp-3050	1123	9	dt	dt	PROPN
fnp-3050	1123	10	,	,	PUNCT
fnp-3050	1123	11	fought	fight	VERB
fnp-3050	1123	12	aj	aj	PROPN
fnp-3050	1123	13	,	,	PUNCT
fnp-3050	1123	14	martersteck	martersteck	VERB
fnp-3050	1123	15	a	a	PRON
fnp-3050	1123	16	,	,	PUNCT
fnp-3050	1123	17	coventry	coventry	NOUN
fnp-3050	1123	18	c	c	PROPN
fnp-3050	1123	19	,	,	PUNCT
fnp-3050	1123	20	sridhar	sridhar	PROPN
fnp-3050	1123	21	j	j	PROPN
fnp-3050	1123	22	,	,	PUNCT
fnp-3050	1123	23	gefen	gefen	PROPN
fnp-3050	1123	24	t	t	PROPN
fnp-3050	1123	25	,	,	PUNCT
fnp-3050	1123	26	weintraub	weintraub	PROPN
fnp-3050	1123	27	s	s	PROPN
fnp-3050	1123	28	,	,	PUNCT
fnp-3050	1123	29	bigio	bigio	NOUN
fnp-3050	1123	30	e	e	NOUN
fnp-3050	1123	31	,	,	PUNCT
fnp-3050	1123	32	mesulam	mesulam	PROPN
fnp-3050	1123	33	mm	mm	PROPN
fnp-3050	1123	34	,	,	PUNCT
fnp-3050	1123	35	rogalski	rogalski	NOUN
fnp-3050	1123	36	e	e	PROPN
fnp-3050	1123	37	,	,	PUNCT
fnp-3050	1123	38	geula	geula	PROPN
fnp-3050	1123	39	c	c	X
fnp-3050	1123	40	(	(	PUNCT
fnp-3050	1123	41	2020	2020	NUM
fnp-3050	1123	42	)	)	PUNCT
fnp-3050	1123	43	accumulation	accumulation	NOUN
fnp-3050	1123	44	of	of	ADP
fnp-3050	1123	45	neurofibrillary	neurofibrillary	ADJ
fnp-3050	1123	46	tangles	tangle	NOUN
fnp-3050	1123	47	and	and	CCONJ
fnp-3050	1123	48	activated	activate	VERB
fnp-3050	1123	49	microglia	microglia	NOUN
fnp-3050	1123	50	is	be	AUX
fnp-3050	1123	51	associated	associate	VERB
fnp-3050	1123	52	with	with	ADP
fnp-3050	1123	53	lower	low	ADJ
fnp-3050	1123	54	neuron	neuron	NOUN
fnp-3050	1123	55	densities	density	NOUN
fnp-3050	1123	56	in	in	ADP
fnp-3050	1123	57	the	the	DET
fnp-3050	1123	58	aphasic	aphasic	ADJ
fnp-3050	1123	59	variant	variant	NOUN
fnp-3050	1123	60	of	of	ADP
fnp-3050	1123	61	alzheimer	alzheimer	PROPN
fnp-3050	1123	62	's	's	PART
fnp-3050	1123	63	disease	disease	NOUN
fnp-3050	1123	64	.	.	PUNCT
fnp-3050	1124	1	brain	brain	NOUN
fnp-3050	1124	2	pathol	pathol	VERB
fnp-3050	1124	3	292	292	NUM
fnp-3050	1124	4	.	.	PUNCT
fnp-3050	1125	1	jellinger	jellinger	PROPN
fnp-3050	1125	2	ka	ka	PROPN
fnp-3050	1125	3	,	,	PUNCT
fnp-3050	1125	4	attems	attem	VERB
fnp-3050	1125	5	j	j	PROPN
fnp-3050	1125	6	(	(	PUNCT
fnp-3050	1125	7	2007	2007	NUM
fnp-3050	1125	8	)	)	PUNCT
fnp-3050	1125	9	neuropathological	neuropathological	ADJ
fnp-3050	1125	10	evaluation	evaluation	NOUN
fnp-3050	1125	11	of	of	ADP
fnp-3050	1125	12	mixed	mixed	ADJ
fnp-3050	1125	13	dementia	dementia	NOUN
fnp-3050	1125	14	.	.	PUNCT
fnp-3050	1126	1	j	j	PROPN
fnp-3050	1126	2	neurol	neurol	PROPN
fnp-3050	1126	3	sci	sci	PROPN
fnp-3050	1126	4	257:80	257:80	PROPN
fnp-3050	1126	5	-	-	SYM
fnp-3050	1126	6	87	87	NUM
fnp-3050	1126	7	293	293	NUM
fnp-3050	1126	8	.	.	PUNCT
fnp-3050	1127	1	kapasi	kapasi	PROPN
fnp-3050	1127	2	a	a	PRON
fnp-3050	1127	3	,	,	PUNCT
fnp-3050	1127	4	decarli	decarli	PROPN
fnp-3050	1127	5	c	c	NOUN
fnp-3050	1127	6	,	,	PUNCT
fnp-3050	1127	7	schneider	schneider	PROPN
fnp-3050	1127	8	ja	ja	PROPN
fnp-3050	1127	9	(	(	PUNCT
fnp-3050	1127	10	2017	2017	NUM
fnp-3050	1127	11	)	)	PUNCT
fnp-3050	1127	12	impact	impact	NOUN
fnp-3050	1127	13	of	of	ADP
fnp-3050	1127	14	multiple	multiple	ADJ
fnp-3050	1127	15	pathologies	pathology	NOUN
fnp-3050	1127	16	on	on	ADP
fnp-3050	1127	17	the	the	DET
fnp-3050	1127	18	threshold	threshold	NOUN
fnp-3050	1127	19	for	for	ADP
fnp-3050	1127	20	clinically	clinically	ADV
fnp-3050	1127	21	overt	overt	ADJ
fnp-3050	1127	22	dementia	dementia	NOUN
fnp-3050	1127	23	.	.	PUNCT
fnp-3050	1128	1	acta	acta	PROPN
fnp-3050	1128	2	neuropathol	neuropathol	PROPN
fnp-3050	1128	3	134:171	134:171	PROPN
fnp-3050	1128	4	-	-	SYM
fnp-3050	1128	5	186	186	NUM
fnp-3050	1128	6	294	294	NUM
fnp-3050	1128	7	.	.	PUNCT
fnp-3050	1129	1	power	power	PROPN
fnp-3050	1129	2	mc	mc	PROPN
fnp-3050	1129	3	,	,	PUNCT
fnp-3050	1129	4	mormino	mormino	PROPN
fnp-3050	1129	5	e	e	PROPN
fnp-3050	1129	6	,	,	PUNCT
fnp-3050	1129	7	soldan	soldan	PROPN
fnp-3050	1129	8	a	a	PROPN
fnp-3050	1129	9	,	,	PUNCT
fnp-3050	1129	10	james	james	PROPN
fnp-3050	1129	11	bd	bd	PROPN
fnp-3050	1129	12	,	,	PUNCT
fnp-3050	1129	13	yu	yu	PROPN
fnp-3050	1129	14	l	l	PROPN
fnp-3050	1129	15	,	,	PUNCT
fnp-3050	1129	16	armstrong	armstrong	PROPN
fnp-3050	1129	17	nm	nm	PROPN
fnp-3050	1129	18	,	,	PUNCT
fnp-3050	1129	19	bangen	bangen	PROPN
fnp-3050	1129	20	kj	kj	PROPN
fnp-3050	1129	21	,	,	PUNCT
fnp-3050	1129	22	delano	delano	PROPN
fnp-3050	1129	23	-	-	PUNCT
fnp-3050	1129	24	wood	wood	PROPN
fnp-3050	1129	25	l	l	NOUN
fnp-3050	1129	26	,	,	PUNCT
fnp-3050	1129	27	lamar	lamar	PROPN
fnp-3050	1129	28	m	m	PROPN
fnp-3050	1129	29	,	,	PUNCT
fnp-3050	1129	30	lim	lim	PROPN
fnp-3050	1129	31	yy	yy	PROPN
fnp-3050	1129	32	,	,	PUNCT
fnp-3050	1129	33	nudelman	nudelman	NOUN
fnp-3050	1129	34	k	k	NOUN
fnp-3050	1129	35	,	,	PUNCT
fnp-3050	1129	36	zahodne	zahodne	PROPN
fnp-3050	1129	37	l	l	NOUN
fnp-3050	1129	38	,	,	PUNCT
fnp-3050	1129	39	gross	gross	PROPN
fnp-3050	1129	40	al	al	PROPN
fnp-3050	1129	41	,	,	PUNCT
fnp-3050	1129	42	mungas	mungas	NOUN
fnp-3050	1129	43	d	d	NOUN
fnp-3050	1129	44	,	,	PUNCT
fnp-3050	1129	45	widaman	widaman	NOUN
fnp-3050	1129	46	kf	kf	PROPN
fnp-3050	1129	47	,	,	PUNCT
fnp-3050	1129	48	schneider	schneider	PROPN
fnp-3050	1129	49	j	j	PROPN
fnp-3050	1129	50	(	(	PUNCT
fnp-3050	1129	51	2018	2018	NUM
fnp-3050	1129	52	)	)	PUNCT
fnp-3050	1129	53	combined	combine	VERB
fnp-3050	1129	54	neuropathological	neuropathological	ADJ
fnp-3050	1129	55	pathways	pathway	NOUN
fnp-3050	1129	56	account	account	VERB
fnp-3050	1129	57	for	for	ADP
fnp-3050	1129	58	age	age	NOUN
fnp-3050	1129	59	-	-	PUNCT
fnp-3050	1129	60	related	relate	VERB
fnp-3050	1129	61	risk	risk	NOUN
fnp-3050	1129	62	of	of	ADP
fnp-3050	1129	63	dementia	dementia	NOUN
fnp-3050	1129	64	.	.	PUNCT
fnp-3050	1130	1	ann	ann	PROPN
fnp-3050	1130	2	neurol	neurol	PROPN
fnp-3050	1130	3	84:10	84:10	NUM
fnp-3050	1130	4	-	-	SYM
fnp-3050	1130	5	22	22	NUM
fnp-3050	1130	6	295	295	NUM
fnp-3050	1130	7	.	.	PUNCT
fnp-3050	1131	1	rahimi	rahimi	PROPN
fnp-3050	1131	2	j	j	PROPN
fnp-3050	1131	3	,	,	PUNCT
fnp-3050	1131	4	kovacs	kovacs	PROPN
fnp-3050	1131	5	gg	gg	PROPN
fnp-3050	1131	6	(	(	PUNCT
fnp-3050	1131	7	2014	2014	NUM
fnp-3050	1131	8	)	)	PUNCT
fnp-3050	1131	9	prevalence	prevalence	NOUN
fnp-3050	1131	10	of	of	ADP
fnp-3050	1131	11	mixed	mixed	ADJ
fnp-3050	1131	12	pathologies	pathology	NOUN
fnp-3050	1131	13	in	in	ADP
fnp-3050	1131	14	the	the	DET
fnp-3050	1131	15	aging	age	VERB
fnp-3050	1131	16	brain	brain	NOUN
fnp-3050	1131	17	.	.	PUNCT
fnp-3050	1132	1	alzheimers	alzheimer	NOUN
fnp-3050	1132	2	res	re	VERB
fnp-3050	1132	3	ther	ther	ADV
fnp-3050	1132	4	6:82	6:82	NUM
fnp-3050	1132	5	296	296	NUM
fnp-3050	1132	6	.	.	PUNCT
fnp-3050	1133	1	matej	matej	PROPN
fnp-3050	1133	2	r	r	PROPN
fnp-3050	1133	3	,	,	PUNCT
fnp-3050	1133	4	tesar	tesar	NOUN
fnp-3050	1133	5	a	a	PRON
fnp-3050	1133	6	,	,	PUNCT
fnp-3050	1133	7	rusina	rusina	ADJ
fnp-3050	1133	8	r	r	PROPN
fnp-3050	1133	9	(	(	PUNCT
fnp-3050	1133	10	2019	2019	NUM
fnp-3050	1133	11	)	)	PUNCT
fnp-3050	1133	12	alzheimer	alzheimer	PROPN
fnp-3050	1133	13	's	's	PART
fnp-3050	1133	14	disease	disease	NOUN
fnp-3050	1133	15	and	and	CCONJ
fnp-3050	1133	16	other	other	ADJ
fnp-3050	1133	17	neurodegenerative	neurodegenerative	ADJ
fnp-3050	1133	18	dementias	dementia	NOUN
fnp-3050	1133	19	in	in	ADP
fnp-3050	1133	20	comorbidity	comorbidity	NOUN
fnp-3050	1133	21	:	:	PUNCT
fnp-3050	1133	22	a	a	DET
fnp-3050	1133	23	clinical	clinical	ADJ
fnp-3050	1133	24	and	and	CCONJ
fnp-3050	1133	25	neuropathological	neuropathological	ADJ
fnp-3050	1133	26	overview	overview	NOUN
fnp-3050	1133	27	.	.	PUNCT
fnp-3050	1134	1	clin	clin	PROPN
fnp-3050	1134	2	biochem	biochem	PROPN
fnp-3050	1134	3	73:26	73:26	NUM
fnp-3050	1134	4	-	-	SYM
fnp-3050	1134	5	31	31	NUM
fnp-3050	1134	6	297	297	NUM
fnp-3050	1134	7	.	.	PUNCT
fnp-3050	1135	1	robinson	robinson	PROPN
fnp-3050	1135	2	jl	jl	PROPN
fnp-3050	1135	3	,	,	PUNCT
fnp-3050	1135	4	lee	lee	PROPN
fnp-3050	1135	5	eb	eb	PROPN
fnp-3050	1135	6	,	,	PUNCT
fnp-3050	1135	7	xie	xie	PROPN
fnp-3050	1135	8	sx	sx	PROPN
fnp-3050	1135	9	,	,	PUNCT
fnp-3050	1135	10	rennert	rennert	PROPN
fnp-3050	1135	11	l	l	PROPN
fnp-3050	1135	12	,	,	PUNCT
fnp-3050	1135	13	suh	suh	PROPN
fnp-3050	1135	14	e	e	PROPN
fnp-3050	1135	15	,	,	PUNCT
fnp-3050	1135	16	bredenberg	bredenberg	PROPN
fnp-3050	1135	17	c	c	X
fnp-3050	1135	18	,	,	PUNCT
fnp-3050	1135	19	caswell	caswell	PROPN
fnp-3050	1135	20	c	c	PROPN
fnp-3050	1135	21	,	,	PUNCT
fnp-3050	1135	22	van	van	PROPN
fnp-3050	1135	23	deerlin	deerlin	PROPN
fnp-3050	1135	24	vm	vm	PROPN
fnp-3050	1135	25	,	,	PUNCT
fnp-3050	1135	26	yan	yan	PROPN
fnp-3050	1135	27	n	n	CCONJ
fnp-3050	1135	28	,	,	PUNCT
fnp-3050	1135	29	yousef	yousef	PROPN
fnp-3050	1135	30	a	a	PROPN
fnp-3050	1135	31	,	,	PUNCT
fnp-3050	1135	32	hurtig	hurtig	PROPN
fnp-3050	1135	33	hi	hi	PROPN
fnp-3050	1135	34	,	,	PUNCT
fnp-3050	1135	35	siderowf	siderowf	NOUN
fnp-3050	1135	36	a	a	PRON
fnp-3050	1135	37	,	,	PUNCT
fnp-3050	1135	38	grossman	grossman	PROPN
fnp-3050	1135	39	m	m	PROPN
fnp-3050	1135	40	,	,	PUNCT
fnp-3050	1135	41	mcmillan	mcmillan	PROPN
fnp-3050	1135	42	ct	ct	PROPN
fnp-3050	1135	43	,	,	PUNCT
fnp-3050	1135	44	miller	miller	PROPN
fnp-3050	1135	45	b	b	PROPN
fnp-3050	1135	46	,	,	PUNCT
fnp-3050	1135	47	duda	duda	PROPN
fnp-3050	1135	48	je	je	PROPN
fnp-3050	1135	49	,	,	PUNCT
fnp-3050	1135	50	irwin	irwin	PROPN
fnp-3050	1135	51	dj	dj	PROPN
fnp-3050	1135	52	,	,	PUNCT
fnp-3050	1135	53	wolk	wolk	NOUN
fnp-3050	1135	54	d	d	PROPN
fnp-3050	1135	55	,	,	PUNCT
fnp-3050	1135	56	elman	elman	PROPN
fnp-3050	1135	57	l	l	PROPN
fnp-3050	1135	58	,	,	PUNCT
fnp-3050	1135	59	mccluskey	mccluskey	PROPN
fnp-3050	1135	60	l	l	PROPN
fnp-3050	1135	61	,	,	PUNCT
fnp-3050	1135	62	chen	chen	PROPN
fnp-3050	1135	63	-	-	PUNCT
fnp-3050	1135	64	plotkin	plotkin	PROPN
fnp-3050	1135	65	a	a	PROPN
fnp-3050	1135	66	,	,	PUNCT
fnp-3050	1135	67	weintraub	weintraub	PROPN
fnp-3050	1135	68	d	d	PROPN
fnp-3050	1135	69	,	,	PUNCT
fnp-3050	1135	70	arnold	arnold	PROPN
fnp-3050	1135	71	se	se	PROPN
fnp-3050	1135	72	,	,	PUNCT
fnp-3050	1135	73	brettschneider	brettschneider	PROPN
fnp-3050	1135	74	j	j	PROPN
fnp-3050	1135	75	,	,	PUNCT
fnp-3050	1135	76	lee	lee	PROPN
fnp-3050	1135	77	vm	vm	PROPN
fnp-3050	1135	78	,	,	PUNCT
fnp-3050	1135	79	trojanowski	trojanowski	PROPN
fnp-3050	1135	80	jq	jq	PROPN
fnp-3050	1135	81	(	(	PUNCT
fnp-3050	1135	82	2018	2018	NUM
fnp-3050	1135	83	)	)	PUNCT
fnp-3050	1135	84	neurodegenerative	neurodegenerative	ADJ
fnp-3050	1135	85	disease	disease	NOUN
fnp-3050	1135	86	concomitant	concomitant	ADJ
fnp-3050	1135	87	proteinopathies	proteinopathie	NOUN
fnp-3050	1135	88	are	be	AUX
fnp-3050	1135	89	prevalent	prevalent	ADJ
fnp-3050	1135	90	,	,	PUNCT
fnp-3050	1135	91	age	age	NOUN
fnp-3050	1135	92	-	-	PUNCT
fnp-3050	1135	93	related	relate	VERB
fnp-3050	1135	94	and	and	CCONJ
fnp-3050	1135	95	apoe4	apoe4	PROPN
fnp-3050	1135	96	-	-	PUNCT
fnp-3050	1135	97	associated	associate	VERB
fnp-3050	1135	98	.	.	PUNCT
fnp-3050	1136	1	brain	brain	NOUN
fnp-3050	1136	2	141:2181	141:2181	NUM
fnp-3050	1136	3	-	-	SYM
fnp-3050	1136	4	2193	2193	NUM
fnp-3050	1136	5	298	298	NUM
fnp-3050	1136	6	.	.	PUNCT
fnp-3050	1137	1	thomas	thomas	PROPN
fnp-3050	1137	2	dx	dx	PROPN
fnp-3050	1137	3	,	,	PUNCT
fnp-3050	1137	4	bajaj	bajaj	PROPN
fnp-3050	1137	5	s	s	PROPN
fnp-3050	1137	6	,	,	PUNCT
fnp-3050	1137	7	mcrae	mcrae	PROPN
fnp-3050	1137	8	-	-	PUNCT
fnp-3050	1137	9	mckee	mckee	PROPN
fnp-3050	1137	10	k	k	PROPN
fnp-3050	1137	11	,	,	PUNCT
fnp-3050	1137	12	hadjichrysanthou	hadjichrysanthou	VERB
fnp-3050	1137	13	c	c	PROPN
fnp-3050	1137	14	,	,	PUNCT
fnp-3050	1137	15	anderson	anderson	PROPN
fnp-3050	1137	16	rm	rm	PROPN
fnp-3050	1137	17	,	,	PUNCT
fnp-3050	1137	18	collinge	collinge	NOUN
fnp-3050	1137	19	j	j	PROPN
fnp-3050	1137	20	(	(	PUNCT
fnp-3050	1137	21	2020	2020	NUM
fnp-3050	1137	22	)	)	PUNCT
fnp-3050	1137	23	association	association	NOUN
fnp-3050	1137	24	of	of	ADP
fnp-3050	1137	25	tdp-43	tdp-43	PROPN
fnp-3050	1137	26	proteinopathy	proteinopathy	ADJ
fnp-3050	1137	27	,	,	PUNCT
fnp-3050	1137	28	cerebral	cerebral	ADJ
fnp-3050	1137	29	amyloid	amyloid	NOUN
fnp-3050	1137	30	angiopathy	angiopathy	NOUN
fnp-3050	1137	31	,	,	PUNCT
fnp-3050	1137	32	and	and	CCONJ
fnp-3050	1137	33	lewy	lewy	PROPN
fnp-3050	1137	34	bodies	body	NOUN
fnp-3050	1137	35	with	with	ADP
fnp-3050	1137	36	cognitive	cognitive	ADJ
fnp-3050	1137	37	impairment	impairment	NOUN
fnp-3050	1137	38	in	in	ADP
fnp-3050	1137	39	individuals	individual	NOUN
fnp-3050	1137	40	with	with	ADP
fnp-3050	1137	41	or	or	CCONJ
fnp-3050	1137	42	without	without	ADP
fnp-3050	1137	43	alzheimer	alzheimer	PROPN
fnp-3050	1137	44	's	's	PART
fnp-3050	1137	45	disease	disease	NOUN
fnp-3050	1137	46	neuropathology	neuropathology	NOUN
fnp-3050	1137	47	.	.	PUNCT
fnp-3050	1138	1	sci	sci	PROPN
fnp-3050	1138	2	rep	rep	PROPN
fnp-3050	1138	3	10:14579	10:14579	PROPN
fnp-3050	1138	4	299	299	NUM
fnp-3050	1138	5	.	.	PUNCT
fnp-3050	1139	1	boyle	boyle	PROPN
fnp-3050	1139	2	pa	pa	PROPN
fnp-3050	1139	3	,	,	PUNCT
fnp-3050	1139	4	yu	yu	PROPN
fnp-3050	1139	5	l	l	PROPN
fnp-3050	1139	6	,	,	PUNCT
fnp-3050	1139	7	wilson	wilson	PROPN
fnp-3050	1139	8	rs	rs	PROPN
fnp-3050	1139	9	,	,	PUNCT
fnp-3050	1139	10	leurgans	leurgan	NOUN
fnp-3050	1139	11	se	se	PROPN
fnp-3050	1139	12	,	,	PUNCT
fnp-3050	1139	13	schneider	schneider	PROPN
fnp-3050	1139	14	ja	ja	PROPN
fnp-3050	1139	15	,	,	PUNCT
fnp-3050	1139	16	bennett	bennett	PROPN
fnp-3050	1139	17	da	da	PROPN
fnp-3050	1139	18	(	(	PUNCT
fnp-3050	1139	19	2018	2018	NUM
fnp-3050	1139	20	)	)	PUNCT
fnp-3050	1139	21	person	person	NOUN
fnp-3050	1139	22	-	-	PUNCT
fnp-3050	1139	23	specific	specific	ADJ
fnp-3050	1139	24	contribution	contribution	NOUN
fnp-3050	1139	25	of	of	ADP
fnp-3050	1139	26	neuropathologies	neuropathologie	NOUN
fnp-3050	1139	27	to	to	PART
fnp-3050	1139	28	cognitive	cognitive	ADJ
fnp-3050	1139	29	loss	loss	NOUN
fnp-3050	1139	30	in	in	ADP
fnp-3050	1139	31	old	old	ADJ
fnp-3050	1139	32	age	age	NOUN
fnp-3050	1139	33	.	.	PUNCT
fnp-3050	1140	1	ann	ann	PROPN
fnp-3050	1140	2	neurol	neurol	PROPN
fnp-3050	1140	3	83:74	83:74	NUM
fnp-3050	1140	4	-	-	SYM
fnp-3050	1140	5	83	83	NUM
fnp-3050	1140	6	300	300	NUM
fnp-3050	1140	7	.	.	PUNCT
fnp-3050	1141	1	schneider	schneider	PROPN
fnp-3050	1141	2	ja	ja	PROPN
fnp-3050	1141	3	,	,	PUNCT
fnp-3050	1141	4	arvanitakis	arvanitakis	PROPN
fnp-3050	1141	5	z	z	PROPN
fnp-3050	1141	6	,	,	PUNCT
fnp-3050	1141	7	bang	bang	PROPN
fnp-3050	1141	8	w	w	PROPN
fnp-3050	1141	9	,	,	PUNCT
fnp-3050	1141	10	bennett	bennett	PROPN
fnp-3050	1141	11	da	da	PROPN
fnp-3050	1141	12	(	(	PUNCT
fnp-3050	1141	13	2007	2007	NUM
fnp-3050	1141	14	)	)	PUNCT
fnp-3050	1141	15	mixed	mixed	ADJ
fnp-3050	1141	16	brain	brain	NOUN
fnp-3050	1141	17	pathologies	pathology	NOUN
fnp-3050	1141	18	account	account	VERB
fnp-3050	1141	19	for	for	ADP
fnp-3050	1141	20	most	most	ADJ
fnp-3050	1141	21	dementia	dementia	NOUN
fnp-3050	1141	22	cases	case	NOUN
fnp-3050	1141	23	in	in	ADP
fnp-3050	1141	24	community	community	NOUN
fnp-3050	1141	25	-	-	PUNCT
fnp-3050	1141	26	dwelling	dwell	VERB
fnp-3050	1141	27	older	old	ADJ
fnp-3050	1141	28	persons	person	NOUN
fnp-3050	1141	29	.	.	PUNCT
fnp-3050	1142	1	neurology	neurology	NOUN
fnp-3050	1142	2	69:2197	69:2197	PROPN
fnp-3050	1142	3	-	-	PUNCT
fnp-3050	1142	4	2204	2204	NUM
fnp-3050	1142	5	301	301	NUM
fnp-3050	1142	6	.	.	PUNCT
fnp-3050	1143	1	jellinger	jellinger	PROPN
fnp-3050	1143	2	ka	ka	PROPN
fnp-3050	1143	3	(	(	PUNCT
fnp-3050	1143	4	2006	2006	NUM
fnp-3050	1143	5	)	)	PUNCT
fnp-3050	1143	6	clinicopathological	clinicopathological	ADJ
fnp-3050	1143	7	analysis	analysis	NOUN
fnp-3050	1143	8	of	of	ADP
fnp-3050	1143	9	dementia	dementia	NOUN
fnp-3050	1143	10	disorders	disorder	NOUN
fnp-3050	1143	11	in	in	ADP
fnp-3050	1143	12	the	the	DET
fnp-3050	1143	13	elderly	elderly	ADJ
fnp-3050	1143	14	--	--	PUNCT
fnp-3050	1143	15	an	an	DET
fnp-3050	1143	16	update	update	NOUN
fnp-3050	1143	17	.	.	PUNCT
fnp-3050	1144	1	j	j	PROPN
fnp-3050	1144	2	alzheimers	alzheimers	PROPN
fnp-3050	1144	3	dis	dis	PROPN
fnp-3050	1144	4	9:61	9:61	NUM
fnp-3050	1144	5	-	-	SYM
fnp-3050	1144	6	70	70	NUM
fnp-3050	1144	7	302	302	NUM
fnp-3050	1144	8	.	.	PUNCT
fnp-3050	1145	1	wang	wang	PROPN
fnp-3050	1145	2	bw	bw	PROPN
fnp-3050	1145	3	,	,	PUNCT
fnp-3050	1145	4	lu	lu	PROPN
fnp-3050	1145	5	e	e	NOUN
fnp-3050	1145	6	,	,	PUNCT
fnp-3050	1145	7	mackenzie	mackenzie	PROPN
fnp-3050	1145	8	ir	ir	PROPN
fnp-3050	1145	9	,	,	PUNCT
fnp-3050	1145	10	assaly	assaly	NOUN
fnp-3050	1145	11	m	m	PROPN
fnp-3050	1145	12	,	,	PUNCT
fnp-3050	1145	13	jacova	jacova	VERB
fnp-3050	1145	14	c	c	X
fnp-3050	1145	15	,	,	PUNCT
fnp-3050	1145	16	lee	lee	PROPN
fnp-3050	1145	17	pe	pe	PROPN
fnp-3050	1145	18	,	,	PUNCT
fnp-3050	1145	19	beattie	beattie	PROPN
fnp-3050	1145	20	bl	bl	PROPN
fnp-3050	1145	21	,	,	PUNCT
fnp-3050	1145	22	hsiung	hsiung	PROPN
fnp-3050	1145	23	gy	gy	PROPN
fnp-3050	1145	24	(	(	PUNCT
fnp-3050	1145	25	2012	2012	NUM
fnp-3050	1145	26	)	)	PUNCT
fnp-3050	1145	27	multiple	multiple	ADJ
fnp-3050	1145	28	pathologies	pathology	NOUN
fnp-3050	1145	29	are	be	AUX
fnp-3050	1145	30	common	common	ADJ
fnp-3050	1145	31	in	in	ADP
fnp-3050	1145	32	alzheimer	alzheimer	PROPN
fnp-3050	1145	33	patients	patient	NOUN
fnp-3050	1145	34	in	in	ADP
fnp-3050	1145	35	clinical	clinical	ADJ
fnp-3050	1145	36	trials	trial	NOUN
fnp-3050	1145	37	.	.	PUNCT
fnp-3050	1146	1	can	can	AUX
fnp-3050	1146	2	j	j	PROPN
fnp-3050	1146	3	neurol	neurol	VERB
fnp-3050	1146	4	sci	sci	PROPN
fnp-3050	1146	5	39:592	39:592	PROPN
fnp-3050	1146	6	-	-	SYM
fnp-3050	1146	7	599	599	NUM
fnp-3050	1146	8	303	303	NUM
fnp-3050	1146	9	.	.	PUNCT
fnp-3050	1147	1	mcaleese	mcaleese	PROPN
fnp-3050	1147	2	ke	ke	PROPN
fnp-3050	1147	3	,	,	PUNCT
fnp-3050	1147	4	walker	walker	PROPN
fnp-3050	1147	5	l	l	PROPN
fnp-3050	1147	6	,	,	PUNCT
fnp-3050	1147	7	erskine	erskine	PROPN
fnp-3050	1147	8	d	d	PROPN
fnp-3050	1147	9	,	,	PUNCT
fnp-3050	1147	10	johnson	johnson	PROPN
fnp-3050	1147	11	m	m	PROPN
fnp-3050	1147	12	,	,	PUNCT
fnp-3050	1147	13	koss	koss	PROPN
fnp-3050	1147	14	d	d	PROPN
fnp-3050	1147	15	,	,	PUNCT
fnp-3050	1147	16	thomas	thomas	PROPN
fnp-3050	1147	17	aj	aj	PROPN
fnp-3050	1147	18	,	,	PUNCT
fnp-3050	1147	19	attems	attem	VERB
fnp-3050	1147	20	j	j	PROPN
fnp-3050	1147	21	(	(	PUNCT
fnp-3050	1147	22	2020	2020	NUM
fnp-3050	1147	23	)	)	PUNCT
fnp-3050	1147	24	concomitant	concomitant	ADJ
fnp-3050	1147	25	late	late	ADJ
fnp-3050	1147	26	-	-	PUNCT
fnp-3050	1147	27	nc	nc	PROPN
fnp-3050	1147	28	in	in	ADP
fnp-3050	1147	29	alzheimer	alzheimer	PROPN
fnp-3050	1147	30	's	's	PART
fnp-3050	1147	31	disease	disease	NOUN
fnp-3050	1147	32	is	be	AUX
fnp-3050	1147	33	not	not	PART
fnp-3050	1147	34	associated	associate	VERB
fnp-3050	1147	35	with	with	ADP
fnp-3050	1147	36	increased	increase	VERB
fnp-3050	1147	37	tau	tau	PROPN
fnp-3050	1147	38	or	or	CCONJ
fnp-3050	1147	39	amyloid	amyloid	NOUN
fnp-3050	1147	40	-	-	PUNCT
fnp-3050	1147	41	beta	beta	ADJ
fnp-3050	1147	42	pathological	pathological	ADJ
fnp-3050	1147	43	burden	burden	NOUN
fnp-3050	1147	44	.	.	PUNCT
fnp-3050	1148	1	neuropathol	neuropathol	NOUN
fnp-3050	1148	2	appl	appl	PROPN
fnp-3050	1148	3	neurobiol	neurobiol	PROPN
fnp-3050	1148	4	online	online	PROPN
fnp-3050	1148	5	sep	sep	PROPN
fnp-3050	1148	6	8	8	NUM
fnp-3050	1148	7	:	:	PUNCT
fnp-3050	1148	8	doi	doi	X
fnp-3050	1148	9	10.1111	10.1111	NUM
fnp-3050	1148	10	/	/	SYM
fnp-3050	1148	11	nan.12664	nan.12664	NUM
fnp-3050	1148	12	304	304	NUM
fnp-3050	1148	13	.	.	PUNCT
fnp-3050	1149	1	mcaleese	mcaleese	PROPN
fnp-3050	1149	2	ke	ke	PROPN
fnp-3050	1149	3	,	,	PUNCT
fnp-3050	1149	4	walker	walker	PROPN
fnp-3050	1149	5	l	l	PROPN
fnp-3050	1149	6	,	,	PUNCT
fnp-3050	1149	7	erskine	erskine	PROPN
fnp-3050	1149	8	d	d	PROPN
fnp-3050	1149	9	,	,	PUNCT
fnp-3050	1149	10	attems	attem	VERB
fnp-3050	1149	11	j	j	PROPN
fnp-3050	1149	12	(	(	PUNCT
fnp-3050	1149	13	2020	2020	NUM
fnp-3050	1149	14	)	)	PUNCT
fnp-3050	1149	15	the	the	DET
fnp-3050	1149	16	impact	impact	NOUN
fnp-3050	1149	17	of	of	ADP
fnp-3050	1149	18	concomitant	concomitant	ADJ
fnp-3050	1149	19	late	late	ADJ
fnp-3050	1149	20	-	-	PUNCT
fnp-3050	1149	21	nc	nc	PROPN
fnp-3050	1149	22	on	on	ADP
fnp-3050	1149	23	hyperphosphorylated	hyperphosphorylate	VERB
fnp-3050	1149	24	-	-	PUNCT
fnp-3050	1149	25	s	s	PART
fnp-3050	1149	26	pathology	pathology	NOUN
fnp-3050	1149	27	and	and	CCONJ
fnp-3050	1149	28	cognitive	cognitive	ADJ
fnp-3050	1149	29	decline	decline	NOUN
fnp-3050	1149	30	in	in	ADP
fnp-3050	1149	31	alzheimer	alzheimer	PROPN
fnp-3050	1149	32	's	's	PART
fnp-3050	1149	33	disease	disease	NOUN
fnp-3050	1149	34	(	(	PUNCT
fnp-3050	1149	35	abstract	abstract	ADJ
fnp-3050	1149	36	)	)	PUNCT
fnp-3050	1149	37	.	.	PUNCT
fnp-3050	1150	1	neuropathol	neuropathol	PROPN
fnp-3050	1150	2	appl	appl	PROPN
fnp-3050	1150	3	neurobiol	neurobiol	PROPN
fnp-3050	1150	4	46	46	NUM
fnp-3050	1150	5	(	(	PUNCT
fnp-3050	1150	6	suppl	suppl	ADJ
fnp-3050	1150	7	.	.	PUNCT
fnp-3050	1151	1	1):37	1):37	NUM
fnp-3050	1151	2	305	305	NUM
fnp-3050	1151	3	.	.	PUNCT
fnp-3050	1152	1	jang	jang	PROPN
fnp-3050	1152	2	h	h	PROPN
fnp-3050	1152	3	,	,	PUNCT
fnp-3050	1152	4	kim	kim	PROPN
fnp-3050	1152	5	hj	hj	PROPN
fnp-3050	1152	6	,	,	PUNCT
fnp-3050	1152	7	sim	sim	ADJ
fnp-3050	1152	8	choe	choe	PROPN
fnp-3050	1152	9	y	y	PROPN
fnp-3050	1152	10	,	,	PUNCT
fnp-3050	1152	11	kim	kim	PROPN
fnp-3050	1152	12	sj	sj	PROPN
fnp-3050	1152	13	,	,	PUNCT
fnp-3050	1152	14	park	park	NOUN
fnp-3050	1152	15	s	s	PROPN
fnp-3050	1152	16	,	,	PUNCT
fnp-3050	1152	17	kim	kim	PROPN
fnp-3050	1152	18	y	y	PROPN
fnp-3050	1152	19	,	,	PUNCT
fnp-3050	1152	20	woon	woon	PROPN
fnp-3050	1152	21	kim	kim	PROPN
fnp-3050	1152	22	k	k	PROPN
fnp-3050	1152	23	,	,	PUNCT
fnp-3050	1152	24	hyoung	hyoung	PROPN
fnp-3050	1152	25	lyoo	lyoo	PROPN
fnp-3050	1152	26	c	c	PROPN
fnp-3050	1152	27	,	,	PUNCT
fnp-3050	1152	28	cho	cho	PROPN
fnp-3050	1152	29	h	h	PROPN
fnp-3050	1152	30	,	,	PUNCT
fnp-3050	1152	31	hoon	hoon	PROPN
fnp-3050	1152	32	ryu	ryu	PROPN
fnp-3050	1152	33	y	y	PROPN
fnp-3050	1152	34	,	,	PUNCT
fnp-3050	1152	35	choi	choi	PROPN
fnp-3050	1152	36	jy	jy	PROPN
fnp-3050	1152	37	,	,	PUNCT
fnp-3050	1152	38	decarli	decarli	PROPN
fnp-3050	1152	39	c	c	AUX
fnp-3050	1152	40	,	,	PUNCT
fnp-3050	1152	41	na	na	PART
fnp-3050	1152	42	dl	dl	PROPN
fnp-3050	1152	43	,	,	PUNCT
fnp-3050	1152	44	won	win	VERB
fnp-3050	1152	45	seo	seo	NOUN
fnp-3050	1152	46	s	s	PART
fnp-3050	1152	47	(	(	PUNCT
fnp-3050	1152	48	2020	2020	NUM
fnp-3050	1152	49	)	)	PUNCT
fnp-3050	1152	50	the	the	DET
fnp-3050	1152	51	impact	impact	NOUN
fnp-3050	1152	52	of	of	ADP
fnp-3050	1152	53	amyloid	amyloid	NOUN
fnp-3050	1152	54	-	-	PUNCT
fnp-3050	1152	55	beta	beta	NOUN
fnp-3050	1152	56	or	or	CCONJ
fnp-3050	1152	57	tau	tau	PROPN
fnp-3050	1152	58	on	on	ADP
fnp-3050	1152	59	cognitive	cognitive	ADJ
fnp-3050	1152	60	change	change	NOUN
fnp-3050	1152	61	in	in	ADP
fnp-3050	1152	62	the	the	DET
fnp-3050	1152	63	presence	presence	NOUN
fnp-3050	1152	64	of	of	ADP
fnp-3050	1152	65	severe	severe	ADJ
fnp-3050	1152	66	cerebrovascular	cerebrovascular	ADJ
fnp-3050	1152	67	disease	disease	NOUN
fnp-3050	1152	68	.	.	PUNCT
fnp-3050	1153	1	j	j	PROPN
fnp-3050	1153	2	alzheimers	alzheimers	PROPN
fnp-3050	1153	3	dis	dis	PROPN
fnp-3050	1153	4	306	306	NUM
fnp-3050	1153	5	.	.	PUNCT
fnp-3050	1154	1	malek	malek	PROPN
fnp-3050	1154	2	-	-	PUNCT
fnp-3050	1154	3	ahmadi	ahmadi	PROPN
fnp-3050	1154	4	m	m	PROPN
fnp-3050	1154	5	,	,	PUNCT
fnp-3050	1154	6	perez	perez	PROPN
fnp-3050	1154	7	se	se	PROPN
fnp-3050	1154	8	,	,	PUNCT
fnp-3050	1154	9	chen	chen	PROPN
fnp-3050	1154	10	k	k	PROPN
fnp-3050	1154	11	,	,	PUNCT
fnp-3050	1154	12	mufson	mufson	NOUN
fnp-3050	1154	13	ej	ej	X
fnp-3050	1154	14	(	(	PUNCT
fnp-3050	1154	15	2020	2020	NUM
fnp-3050	1154	16	)	)	PUNCT
fnp-3050	1154	17	braak	braak	NOUN
fnp-3050	1154	18	stage	stage	NOUN
fnp-3050	1154	19	,	,	PUNCT
fnp-3050	1154	20	cerebral	cerebral	ADJ
fnp-3050	1154	21	amyloid	amyloid	NOUN
fnp-3050	1154	22	angiopathy	angiopathy	NOUN
fnp-3050	1154	23	,	,	PUNCT
fnp-3050	1154	24	and	and	CCONJ
fnp-3050	1154	25	cognitive	cognitive	ADJ
fnp-3050	1154	26	decline	decline	NOUN
fnp-3050	1154	27	in	in	ADP
fnp-3050	1154	28	early	early	ADJ
fnp-3050	1154	29	alzheimer	alzheimer	PROPN
fnp-3050	1154	30	's	's	PART
fnp-3050	1154	31	disease	disease	NOUN
fnp-3050	1154	32	.	.	PUNCT
fnp-3050	1155	1	j	j	PROPN
fnp-3050	1155	2	alzheimers	alzheimers	PROPN
fnp-3050	1155	3	dis	dis	PROPN
fnp-3050	1155	4	74:189	74:189	NUM
fnp-3050	1155	5	-	-	SYM
fnp-3050	1155	6	197	197	NUM
fnp-3050	1155	7	307	307	NUM
fnp-3050	1155	8	.	.	PUNCT
fnp-3050	1156	1	robinson	robinson	PROPN
fnp-3050	1156	2	ac	ac	PROPN
fnp-3050	1156	3	,	,	PUNCT
fnp-3050	1156	4	roncaroli	roncaroli	PROPN
fnp-3050	1156	5	f	f	PROPN
fnp-3050	1156	6	,	,	PUNCT
fnp-3050	1156	7	chew	chew	VERB
fnp-3050	1156	8	-	-	PUNCT
fnp-3050	1156	9	graham	graham	PROPN
fnp-3050	1156	10	s	s	PROPN
fnp-3050	1156	11	,	,	PUNCT
fnp-3050	1156	12	davidson	davidson	NOUN
fnp-3050	1156	13	ys	ys	NOUN
fnp-3050	1156	14	,	,	PUNCT
fnp-3050	1156	15	minshull	minshull	NOUN
fnp-3050	1156	16	j	j	PROPN
fnp-3050	1156	17	,	,	PUNCT
fnp-3050	1156	18	horan	horan	PROPN
fnp-3050	1156	19	ma	ma	PROPN
fnp-3050	1156	20	,	,	PUNCT
fnp-3050	1156	21	payton	payton	PROPN
fnp-3050	1156	22	a	a	PRON
fnp-3050	1156	23	,	,	PUNCT
fnp-3050	1156	24	pendleton	pendleton	PROPN
fnp-3050	1156	25	n	n	CCONJ
fnp-3050	1156	26	,	,	PUNCT
fnp-3050	1156	27	mann	mann	PROPN
fnp-3050	1156	28	dma	dma	PROPN
fnp-3050	1156	29	(	(	PUNCT
fnp-3050	1156	30	2020	2020	NUM
fnp-3050	1156	31	)	)	PUNCT
fnp-3050	1156	32	the	the	DET
fnp-3050	1156	33	contribution	contribution	NOUN
fnp-3050	1156	34	of	of	ADP
fnp-3050	1156	35	vascular	vascular	ADJ
fnp-3050	1156	36	pathology	pathology	NOUN
fnp-3050	1156	37	toward	toward	ADP
fnp-3050	1156	38	cognitive	cognitive	ADJ
fnp-3050	1156	39	impairment	impairment	NOUN
fnp-3050	1156	40	in	in	ADP
fnp-3050	1156	41	older	old	ADJ
fnp-3050	1156	42	individuals	individual	NOUN
fnp-3050	1156	43	with	with	ADP
fnp-3050	1156	44	intermediate	intermediate	ADJ
fnp-3050	1156	45	braak	braak	NOUN
fnp-3050	1156	46	stage	stage	NOUN
fnp-3050	1156	47	tau	tau	PROPN
fnp-3050	1156	48	pathology	pathology	PROPN
fnp-3050	1156	49	.	.	PUNCT
fnp-3050	1157	1	j	j	PROPN
fnp-3050	1157	2	alzheimers	alzheimers	PROPN
fnp-3050	1157	3	dis	dis	PROPN
fnp-3050	1158	1	77:1005	77:1005	NUM
fnp-3050	1158	2	-	-	NUM
fnp-3050	1158	3	1015	1015	NUM
fnp-3050	1158	4	308	308	NUM
fnp-3050	1158	5	.	.	PUNCT
fnp-3050	1159	1	gauthreaux	gauthreaux	PROPN
fnp-3050	1159	2	k	k	PROPN
fnp-3050	1159	3	,	,	PUNCT
fnp-3050	1159	4	bonnett	bonnett	PROPN
fnp-3050	1159	5	ta	ta	PROPN
fnp-3050	1159	6	,	,	PUNCT
fnp-3050	1159	7	besser	besser	PROPN
fnp-3050	1159	8	lm	lm	PROPN
fnp-3050	1159	9	,	,	PUNCT
fnp-3050	1159	10	brenowitz	brenowitz	PROPN
fnp-3050	1159	11	wd	wd	PROPN
fnp-3050	1159	12	,	,	PUNCT
fnp-3050	1159	13	teylan	teylan	NOUN
fnp-3050	1159	14	m	m	NOUN
fnp-3050	1159	15	,	,	PUNCT
fnp-3050	1159	16	mock	mock	ADJ
fnp-3050	1159	17	c	c	NOUN
fnp-3050	1159	18	,	,	PUNCT
fnp-3050	1159	19	chen	chen	PROPN
fnp-3050	1159	20	yc	yc	PROPN
fnp-3050	1159	21	,	,	PUNCT
fnp-3050	1159	22	chan	chan	PROPN
fnp-3050	1159	23	kcg	kcg	PROPN
fnp-3050	1159	24	,	,	PUNCT
fnp-3050	1159	25	keene	keene	PROPN
fnp-3050	1159	26	cd	cd	PROPN
fnp-3050	1159	27	,	,	PUNCT
fnp-3050	1159	28	zhou	zhou	PROPN
fnp-3050	1159	29	xh	xh	PROPN
fnp-3050	1159	30	,	,	PUNCT
fnp-3050	1159	31	kukull	kukull	PROPN
fnp-3050	1159	32	wa	wa	PROPN
fnp-3050	1159	33	(	(	PUNCT
fnp-3050	1159	34	2020	2020	NUM
fnp-3050	1159	35	)	)	PUNCT
fnp-3050	1159	36	concordance	concordance	NOUN
fnp-3050	1159	37	of	of	ADP
fnp-3050	1159	38	clinical	clinical	ADJ
fnp-3050	1159	39	alzheimer	alzheimer	NOUN
fnp-3050	1159	40	diagnosis	diagnosis	NOUN
fnp-3050	1159	41	and	and	CCONJ
fnp-3050	1159	42	neuropathological	neuropathological	ADJ
fnp-3050	1159	43	features	feature	NOUN
fnp-3050	1159	44	at	at	ADP
fnp-3050	1159	45	autopsy	autopsy	ADJ
fnp-3050	1159	46	.	.	PUNCT
fnp-3050	1160	1	j	j	PROPN
fnp-3050	1160	2	neuropathol	neuropathol	PROPN
fnp-3050	1160	3	exp	exp	PROPN
fnp-3050	1160	4	neurol	neurol	PROPN
fnp-3050	1160	5	79:465	79:465	PROPN
fnp-3050	1160	6	-	-	PUNCT
fnp-3050	1160	7	473	473	NUM
fnp-3050	1160	8	309	309	NUM
fnp-3050	1160	9	.	.	PUNCT
fnp-3050	1161	1	tolnay	tolnay	PROPN
fnp-3050	1161	2	m	m	PROPN
fnp-3050	1161	3	,	,	PUNCT
fnp-3050	1161	4	sergeant	sergeant	NOUN
fnp-3050	1161	5	n	n	CCONJ
fnp-3050	1161	6	,	,	PUNCT
fnp-3050	1161	7	ghestem	ghestem	NOUN
fnp-3050	1161	8	a	a	NOUN
fnp-3050	1161	9	,	,	PUNCT
fnp-3050	1161	10	chalbot	chalbot	PROPN
fnp-3050	1161	11	s	s	PROPN
fnp-3050	1161	12	,	,	PUNCT
fnp-3050	1161	13	de	de	PROPN
fnp-3050	1161	14	vos	vos	PROPN
fnp-3050	1161	15	ra	ra	PROPN
fnp-3050	1161	16	,	,	PUNCT
fnp-3050	1161	17	jansen	jansen	PROPN
fnp-3050	1161	18	steur	steur	PROPN
fnp-3050	1161	19	en	en	PROPN
fnp-3050	1161	20	,	,	PUNCT
fnp-3050	1161	21	probst	probst	PROPN
fnp-3050	1161	22	a	a	PRON
fnp-3050	1161	23	,	,	PUNCT
fnp-3050	1161	24	delacourte	delacourte	ADJ
fnp-3050	1161	25	a	a	DET
fnp-3050	1161	26	(	(	PUNCT
fnp-3050	1161	27	2002	2002	NUM
fnp-3050	1161	28	)	)	PUNCT
fnp-3050	1161	29	argyrophilic	argyrophilic	ADJ
fnp-3050	1161	30	grain	grain	NOUN
fnp-3050	1161	31	disease	disease	NOUN
fnp-3050	1161	32	and	and	CCONJ
fnp-3050	1161	33	alzheimer	alzheimer	PROPN
fnp-3050	1161	34	's	's	PART
fnp-3050	1161	35	disease	disease	NOUN
fnp-3050	1161	36	are	be	AUX
fnp-3050	1161	37	distinguished	distinguish	VERB
fnp-3050	1161	38	by	by	ADP
fnp-3050	1161	39	their	their	PRON
fnp-3050	1161	40	different	different	ADJ
fnp-3050	1161	41	distribution	distribution	NOUN
fnp-3050	1161	42	of	of	ADP
fnp-3050	1161	43	tau	tau	PROPN
fnp-3050	1161	44	protein	protein	NOUN
fnp-3050	1161	45	isoforms	isoform	NOUN
fnp-3050	1161	46	.	.	PUNCT
fnp-3050	1162	1	acta	acta	PROPN
fnp-3050	1162	2	neuropathol	neuropathol	PROPN
fnp-3050	1162	3	104:425	104:425	NUM
fnp-3050	1162	4	-	-	SYM
fnp-3050	1162	5	434	434	NUM
fnp-3050	1162	6	310	310	NUM
fnp-3050	1162	7	.	.	PUNCT
fnp-3050	1163	1	togo	togo	PROPN
fnp-3050	1163	2	t	t	PROPN
fnp-3050	1163	3	,	,	PUNCT
fnp-3050	1163	4	cookson	cookson	PROPN
fnp-3050	1163	5	n	n	PROPN
fnp-3050	1163	6	,	,	PUNCT
fnp-3050	1163	7	dickson	dickson	PROPN
fnp-3050	1163	8	dw	dw	PROPN
fnp-3050	1163	9	(	(	PUNCT
fnp-3050	1163	10	2002	2002	NUM
fnp-3050	1163	11	)	)	PUNCT
fnp-3050	1163	12	argyrophilic	argyrophilic	ADJ
fnp-3050	1163	13	grain	grain	NOUN
fnp-3050	1163	14	disease	disease	NOUN
fnp-3050	1163	15	:	:	PUNCT
fnp-3050	1163	16	neuropathology	neuropathology	NOUN
fnp-3050	1163	17	,	,	PUNCT
fnp-3050	1163	18	frequency	frequency	NOUN
fnp-3050	1163	19	in	in	ADP
fnp-3050	1163	20	a	a	DET
fnp-3050	1163	21	dementia	dementia	NOUN
fnp-3050	1163	22	brain	brain	NOUN
fnp-3050	1163	23	bank	bank	PROPN
fnp-3050	1163	24	and	and	CCONJ
fnp-3050	1163	25	lack	lack	NOUN
fnp-3050	1163	26	of	of	ADP
fnp-3050	1163	27	relationship	relationship	NOUN
fnp-3050	1163	28	with	with	ADP
fnp-3050	1163	29	apolipoprotein	apolipoprotein	PROPN
fnp-3050	1163	30	e.	e.	PROPN
fnp-3050	1163	31	brain	brain	PROPN
fnp-3050	1163	32	pathol	pathol	PROPN
fnp-3050	1163	33	12:45	12:45	NUM
fnp-3050	1163	34	-	-	SYM
fnp-3050	1163	35	52	52	NUM
fnp-3050	1163	36	311	311	NUM
fnp-3050	1163	37	.	.	PUNCT
fnp-3050	1164	1	wurm	wurm	NOUN
fnp-3050	1164	2	r	r	PROPN
fnp-3050	1164	3	,	,	PUNCT
fnp-3050	1164	4	klotz	klotz	PROPN
fnp-3050	1164	5	s	s	PROPN
fnp-3050	1164	6	,	,	PUNCT
fnp-3050	1164	7	rahimi	rahimi	PROPN
fnp-3050	1164	8	j	j	PROPN
fnp-3050	1164	9	,	,	PUNCT
fnp-3050	1164	10	katzenschlager	katzenschlager	ADJ
fnp-3050	1164	11	r	r	NOUN
fnp-3050	1164	12	,	,	PUNCT
fnp-3050	1164	13	lindeck	lindeck	ADJ
fnp-3050	1164	14	-	-	PUNCT
fnp-3050	1164	15	pozza	pozza	NOUN
fnp-3050	1164	16	e	e	NOUN
fnp-3050	1164	17	,	,	PUNCT
fnp-3050	1164	18	regelsberger	regelsberger	NOUN
fnp-3050	1164	19	g	g	PROPN
fnp-3050	1164	20	,	,	PUNCT
fnp-3050	1164	21	danics	danic	NOUN
fnp-3050	1164	22	k	k	PROPN
fnp-3050	1164	23	,	,	PUNCT
fnp-3050	1164	24	kapas	kapa	VERB
fnp-3050	1164	25	i	i	PRON
fnp-3050	1164	26	,	,	PUNCT
fnp-3050	1164	27	bíró	bíró	PROPN
fnp-3050	1164	28	za	za	PROPN
fnp-3050	1164	29	,	,	PUNCT
fnp-3050	1164	30	stögmann	stögmann	NOUN
fnp-3050	1164	31	e	e	NOUN
fnp-3050	1164	32	,	,	PUNCT
fnp-3050	1164	33	gelpi	gelpi	NOUN
fnp-3050	1164	34	e	e	NOUN
fnp-3050	1164	35	,	,	PUNCT
fnp-3050	1164	36	kovacs	kovacs	PROPN
fnp-3050	1164	37	gg	gg	PROPN
fnp-3050	1164	38	(	(	PUNCT
fnp-3050	1164	39	2020	2020	NUM
fnp-3050	1164	40	)	)	PUNCT
fnp-3050	1164	41	argyrophilic	argyrophilic	ADJ
fnp-3050	1164	42	grain	grain	NOUN
fnp-3050	1164	43	disease	disease	NOUN
fnp-3050	1164	44	in	in	ADP
fnp-3050	1164	45	individuals	individual	NOUN
fnp-3050	1164	46	younger	young	ADJ
fnp-3050	1164	47	than	than	ADP
fnp-3050	1164	48	75	75	NUM
fnp-3050	1164	49	years	year	NOUN
fnp-3050	1164	50	:	:	PUNCT
fnp-3050	1164	51	clinical	clinical	ADJ
fnp-3050	1164	52	variability	variability	NOUN
fnp-3050	1164	53	in	in	ADP
fnp-3050	1164	54	an	an	DET
fnp-3050	1164	55	underrecognized	underrecognized	ADJ
fnp-3050	1164	56	limbic	limbic	ADJ
fnp-3050	1164	57	tauopathy	tauopathy	NOUN
fnp-3050	1164	58	.	.	PUNCT
fnp-3050	1165	1	eur	eur	PROPN
fnp-3050	1165	2	j	j	PROPN
fnp-3050	1165	3	neurol	neurol	PROPN
fnp-3050	1165	4	may	may	AUX
fnp-3050	1165	5	13	13	NUM
fnp-3050	1165	6	:	:	PUNCT
fnp-3050	1165	7	doi	doi	NOUN
fnp-3050	1165	8	:	:	PUNCT
fnp-3050	1165	9	10.1111	10.1111	NUM
fnp-3050	1165	10	/	/	SYM
fnp-3050	1165	11	ene.14321	ene.14321	SYM
fnp-3050	1165	12	312	312	NUM
fnp-3050	1165	13	.	.	PUNCT
fnp-3050	1166	1	ferrer	ferrer	PROPN
fnp-3050	1166	2	i	i	PROPN
fnp-3050	1166	3	,	,	PUNCT
fnp-3050	1166	4	garcia	garcia	PROPN
fnp-3050	1166	5	ma	ma	PROPN
fnp-3050	1166	6	,	,	PUNCT
fnp-3050	1166	7	gonzalez	gonzalez	PROPN
fnp-3050	1166	8	il	il	PROPN
fnp-3050	1166	9	,	,	PUNCT
fnp-3050	1166	10	lucena	lucena	PROPN
fnp-3050	1166	11	dd	dd	PROPN
fnp-3050	1166	12	,	,	PUNCT
fnp-3050	1166	13	villalonga	villalonga	PROPN
fnp-3050	1166	14	ar	ar	PROPN
fnp-3050	1166	15	,	,	PUNCT
fnp-3050	1166	16	tech	tech	PROPN
fnp-3050	1166	17	mc	mc	PROPN
fnp-3050	1166	18	,	,	PUNCT
fnp-3050	1166	19	llorens	llorens	PROPN
fnp-3050	1166	20	f	f	PROPN
fnp-3050	1166	21	,	,	PUNCT
fnp-3050	1166	22	garcia	garcia	PROPN
fnp-3050	1166	23	-	-	PUNCT
fnp-3050	1166	24	esparcia	esparcia	PROPN
fnp-3050	1166	25	p	p	NOUN
fnp-3050	1166	26	,	,	PUNCT
fnp-3050	1166	27	martinez	martinez	PROPN
fnp-3050	1166	28	-	-	PUNCT
fnp-3050	1166	29	maldonado	maldonado	PROPN
fnp-3050	1166	30	a	a	X
fnp-3050	1166	31	,	,	PUNCT
fnp-3050	1166	32	mendez	mendez	PROPN
fnp-3050	1166	33	mf	mf	PROPN
fnp-3050	1166	34	,	,	PUNCT
fnp-3050	1166	35	escribano	escribano	NOUN
fnp-3050	1166	36	bt	bt	NOUN
fnp-3050	1166	37	,	,	PUNCT
fnp-3050	1166	38	bech	bech	PROPN
fnp-3050	1166	39	-	-	PUNCT
fnp-3050	1166	40	serra	serra	PROPN
fnp-3050	1166	41	jj	jj	PROPN
fnp-3050	1166	42	,	,	PUNCT
fnp-3050	1166	43	sabido	sabido	NOUN
fnp-3050	1166	44	e	e	NOUN
fnp-3050	1166	45	,	,	PUNCT
fnp-3050	1166	46	de	de	X
fnp-3050	1166	47	la	la	PROPN
fnp-3050	1166	48	torre	torre	PROPN
fnp-3050	1166	49	gomez	gomez	PROPN
fnp-3050	1166	50	c	c	PROPN
fnp-3050	1166	51	,	,	PUNCT
fnp-3050	1166	52	del	del	PROPN
fnp-3050	1166	53	rio	rio	PROPN
fnp-3050	1166	54	ja	ja	PROPN
fnp-3050	1166	55	(	(	PUNCT
fnp-3050	1166	56	2018	2018	NUM
fnp-3050	1166	57	)	)	PUNCT
fnp-3050	1166	58	aging	age	VERB
fnp-3050	1166	59	-	-	PUNCT
fnp-3050	1166	60	related	relate	VERB
fnp-3050	1166	61	tau	tau	PROPN
fnp-3050	1166	62	astrogliopathy	astrogliopathy	ADJ
fnp-3050	1166	63	(	(	PUNCT
fnp-3050	1166	64	artag	artag	ADJ
fnp-3050	1166	65	):	):	PUNCT
fnp-3050	1166	66	not	not	PART
fnp-3050	1166	67	only	only	ADV
fnp-3050	1166	68	tau	tau	PROPN
fnp-3050	1166	69	phosphorylation	phosphorylation	NOUN
fnp-3050	1166	70	in	in	ADP
fnp-3050	1166	71	astrocytes	astrocyte	NOUN
fnp-3050	1166	72	.	.	PUNCT
fnp-3050	1167	1	brain	brain	NOUN
fnp-3050	1167	2	pathol	pathol	NOUN
fnp-3050	1167	3	28:965	28:965	PROPN
fnp-3050	1167	4	-	-	PUNCT
fnp-3050	1167	5	985	985	NUM
fnp-3050	1167	6	313	313	NUM
fnp-3050	1167	7	.	.	PUNCT
fnp-3050	1168	1	kovacs	kovacs	PROPN
fnp-3050	1168	2	gg	gg	PROPN
fnp-3050	1168	3	(	(	PUNCT
fnp-3050	1168	4	2020	2020	NUM
fnp-3050	1168	5	)	)	PUNCT
fnp-3050	1168	6	astroglia	astroglia	PROPN
fnp-3050	1168	7	and	and	CCONJ
fnp-3050	1168	8	tau	tau	PROPN
fnp-3050	1168	9	:	:	PUNCT
fnp-3050	1168	10	new	new	ADJ
fnp-3050	1168	11	perspectives	perspective	NOUN
fnp-3050	1168	12	.	.	PUNCT
fnp-3050	1169	1	front	front	ADJ
fnp-3050	1169	2	aging	age	VERB
fnp-3050	1169	3	neurosci	neurosci	NOUN
fnp-3050	1169	4	12:96	12:96	NUM
fnp-3050	1169	5	314	314	NUM
fnp-3050	1169	6	.	.	PUNCT
fnp-3050	1170	1	wiersma	wiersma	PROPN
fnp-3050	1170	2	vi	vi	PROPN
fnp-3050	1170	3	,	,	PUNCT
fnp-3050	1170	4	van	van	PROPN
fnp-3050	1170	5	ziel	ziel	PROPN
fnp-3050	1170	6	am	am	PROPN
fnp-3050	1170	7	,	,	PUNCT
fnp-3050	1170	8	vazquez	vazquez	PROPN
fnp-3050	1170	9	-	-	PUNCT
fnp-3050	1170	10	sanchez	sanchez	PROPN
fnp-3050	1170	11	s	s	PART
fnp-3050	1170	12	,	,	PUNCT
fnp-3050	1170	13	nölle	nölle	VERB
fnp-3050	1170	14	a	a	DET
fnp-3050	1170	15	,	,	PUNCT
fnp-3050	1170	16	berenjeno	berenjeno	PROPN
fnp-3050	1170	17	-	-	PUNCT
fnp-3050	1170	18	correa	correa	PROPN
fnp-3050	1170	19	e	e	PROPN
fnp-3050	1170	20	,	,	PUNCT
fnp-3050	1170	21	bonaterra	bonaterra	NOUN
fnp-3050	1170	22	-	-	PUNCT
fnp-3050	1170	23	pastra	pastra	PROPN
fnp-3050	1170	24	a	a	PROPN
fnp-3050	1170	25	,	,	PUNCT
fnp-3050	1170	26	clavaguera	clavaguera	NOUN
fnp-3050	1170	27	f	f	NOUN
fnp-3050	1170	28	,	,	PUNCT
fnp-3050	1170	29	tolnay	tolnay	PROPN
fnp-3050	1170	30	m	m	PROPN
fnp-3050	1170	31	,	,	PUNCT
fnp-3050	1170	32	musters	muster	NOUN
fnp-3050	1170	33	rjp	rjp	NOUN
fnp-3050	1170	34	,	,	PUNCT
fnp-3050	1170	35	van	van	PROPN
fnp-3050	1170	36	weering	weere	VERB
fnp-3050	1170	37	jrt	jrt	PROPN
fnp-3050	1170	38	,	,	PUNCT
fnp-3050	1170	39	verhage	verhage	NOUN
fnp-3050	1170	40	m	m	PROPN
fnp-3050	1170	41	,	,	PUNCT
fnp-3050	1170	42	hoozemans	hoozemans	PROPN
fnp-3050	1170	43	jjm	jjm	PROPN
fnp-3050	1170	44	,	,	PUNCT
fnp-3050	1170	45	scheper	scheper	NOUN
fnp-3050	1170	46	w	w	PROPN
fnp-3050	1170	47	(	(	PUNCT
fnp-3050	1170	48	2019	2019	NUM
fnp-3050	1170	49	)	)	PUNCT
fnp-3050	1170	50	granulovacuolar	granulovacuolar	ADJ
fnp-3050	1170	51	degeneration	degeneration	NOUN
fnp-3050	1170	52	bodies	body	NOUN
fnp-3050	1170	53	are	be	AUX
fnp-3050	1170	54	neuron	neuron	NOUN
fnp-3050	1170	55	-	-	PUNCT
fnp-3050	1170	56	selective	selective	ADJ
fnp-3050	1170	57	lysosomal	lysosomal	ADJ
fnp-3050	1170	58	structures	structure	NOUN
fnp-3050	1170	59	induced	induce	VERB
fnp-3050	1170	60	by	by	ADP
fnp-3050	1170	61	intracellular	intracellular	ADJ
fnp-3050	1170	62	tau	tau	PROPN
fnp-3050	1170	63	pathology	pathology	NOUN
fnp-3050	1170	64	.	.	PUNCT
fnp-3050	1171	1	acta	acta	PROPN
fnp-3050	1171	2	neuropathol	neuropathol	PROPN
fnp-3050	1171	3	138:943	138:943	PROPN
fnp-3050	1171	4	-	-	PUNCT
fnp-3050	1171	5	970	970	NUM
fnp-3050	1171	6	315	315	NUM
fnp-3050	1171	7	.	.	PUNCT
fnp-3050	1172	1	wiersma	wiersma	PROPN
fnp-3050	1172	2	vi	vi	PROPN
fnp-3050	1172	3	,	,	PUNCT
fnp-3050	1172	4	hoozemans	hoozemans	PROPN
fnp-3050	1172	5	jjm	jjm	PROPN
fnp-3050	1172	6	,	,	PUNCT
fnp-3050	1172	7	scheper	scheper	NOUN
fnp-3050	1172	8	w	w	PROPN
fnp-3050	1172	9	(	(	PUNCT
fnp-3050	1172	10	2020	2020	NUM
fnp-3050	1172	11	)	)	PUNCT
fnp-3050	1172	12	untangling	untangle	VERB
fnp-3050	1172	13	the	the	DET
fnp-3050	1172	14	origin	origin	NOUN
fnp-3050	1172	15	and	and	CCONJ
fnp-3050	1172	16	function	function	NOUN
fnp-3050	1172	17	of	of	ADP
fnp-3050	1172	18	granulovacuolar	granulovacuolar	ADJ
fnp-3050	1172	19	degeneration	degeneration	NOUN
fnp-3050	1172	20	bodies	body	NOUN
fnp-3050	1172	21	in	in	ADP
fnp-3050	1172	22	neurodegenerative	neurodegenerative	ADJ
fnp-3050	1172	23	proteinopathies	proteinopathie	NOUN
fnp-3050	1172	24	.	.	PUNCT
fnp-3050	1173	1	acta	acta	PROPN
fnp-3050	1173	2	neuropathol	neuropathol	PROPN
fnp-3050	1173	3	commun	commun	PROPN
fnp-3050	1173	4	8:153	8:153	NUM
fnp-3050	1173	5	316	316	NUM
fnp-3050	1173	6	.	.	PUNCT
fnp-3050	1174	1	hou	hou	PROPN
fnp-3050	1174	2	x	x	PROPN
fnp-3050	1174	3	,	,	PUNCT
fnp-3050	1174	4	fiesel	fiesel	NOUN
fnp-3050	1174	5	fc	fc	PROPN
fnp-3050	1174	6	,	,	PUNCT
fnp-3050	1174	7	truban	truban	PROPN
fnp-3050	1174	8	d	d	PROPN
fnp-3050	1174	9	,	,	PUNCT
fnp-3050	1174	10	castanedes	castanedes	PROPN
fnp-3050	1174	11	casey	casey	PROPN
fnp-3050	1174	12	m	m	PROPN
fnp-3050	1174	13	,	,	PUNCT
fnp-3050	1174	14	lin	lin	PROPN
fnp-3050	1174	15	wl	wl	PROPN
fnp-3050	1174	16	,	,	PUNCT
fnp-3050	1174	17	soto	soto	PROPN
fnp-3050	1174	18	ai	ai	VERB
fnp-3050	1174	19	,	,	PUNCT
fnp-3050	1174	20	tacik	tacik	VERB
fnp-3050	1174	21	p	p	X
fnp-3050	1174	22	,	,	PUNCT
fnp-3050	1174	23	rousseau	rousseau	PROPN
fnp-3050	1174	24	lg	lg	PROPN
fnp-3050	1174	25	,	,	PUNCT
fnp-3050	1174	26	diehl	diehl	PROPN
fnp-3050	1174	27	nn	nn	PROPN
fnp-3050	1174	28	,	,	PUNCT
fnp-3050	1174	29	heckman	heckman	PROPN
fnp-3050	1174	30	mg	mg	PROPN
fnp-3050	1174	31	,	,	PUNCT
fnp-3050	1174	32	lorenzo	lorenzo	NOUN
fnp-3050	1174	33	-	-	PUNCT
fnp-3050	1174	34	betancor	betancor	NOUN
fnp-3050	1174	35	o	o	NOUN
fnp-3050	1174	36	,	,	PUNCT
fnp-3050	1174	37	ferrer	ferrer	PROPN
fnp-3050	1174	38	i	i	PROPN
fnp-3050	1174	39	,	,	PUNCT
fnp-3050	1174	40	arbelo	arbelo	NOUN
fnp-3050	1174	41	jm	jm	PROPN
fnp-3050	1174	42	,	,	PUNCT
fnp-3050	1174	43	steele	steele	PROPN
fnp-3050	1174	44	jc	jc	PROPN
fnp-3050	1174	45	,	,	PUNCT
fnp-3050	1174	46	farrer	farrer	PROPN
fnp-3050	1174	47	mj	mj	PROPN
fnp-3050	1174	48	,	,	PUNCT
fnp-3050	1174	49	cornejo	cornejo	PROPN
fnp-3050	1174	50	-	-	PUNCT
fnp-3050	1174	51	olivas	olivas	PROPN
fnp-3050	1174	52	m	m	PROPN
fnp-3050	1174	53	,	,	PUNCT
fnp-3050	1174	54	torres	torre	VERB
fnp-3050	1174	55	l	l	PROPN
fnp-3050	1174	56	,	,	PUNCT
fnp-3050	1174	57	mata	mata	PROPN
fnp-3050	1174	58	if	if	SCONJ
fnp-3050	1174	59	,	,	PUNCT
fnp-3050	1174	60	graff	graff	NOUN
fnp-3050	1174	61	-	-	PUNCT
fnp-3050	1174	62	radford	radford	PROPN
fnp-3050	1174	63	nr	nr	PROPN
fnp-3050	1174	64	,	,	PUNCT
fnp-3050	1174	65	wszolek	wszolek	VERB
fnp-3050	1174	66	zk	zk	PROPN
fnp-3050	1174	67	,	,	PUNCT
fnp-3050	1174	68	ross	ross	PROPN
fnp-3050	1174	69	oa	oa	PROPN
fnp-3050	1174	70	,	,	PUNCT
fnp-3050	1174	71	murray	murray	VERB
fnp-3050	1174	72	me	i	PRON
fnp-3050	1174	73	,	,	PUNCT
fnp-3050	1174	74	dickson	dickson	PROPN
fnp-3050	1174	75	dw	dw	PROPN
fnp-3050	1174	76	,	,	PUNCT
fnp-3050	1174	77	springer	springer	PROPN
fnp-3050	1174	78	w	w	PROPN
fnp-3050	1174	79	(	(	PUNCT
fnp-3050	1174	80	2018	2018	NUM
fnp-3050	1174	81	)	)	PUNCT
fnp-3050	1174	82	ageand	ageand	NOUN
fnp-3050	1174	83	disease	disease	NOUN
fnp-3050	1174	84	-	-	PUNCT
fnp-3050	1174	85	dependent	dependent	ADJ
fnp-3050	1174	86	increase	increase	NOUN
fnp-3050	1174	87	of	of	ADP
fnp-3050	1174	88	the	the	DET
fnp-3050	1174	89	mitophagy	mitophagy	NOUN
fnp-3050	1174	90	marker	marker	NOUN
fnp-3050	1174	91	phospho	phospho	NOUN
fnp-3050	1174	92	-	-	PUNCT
fnp-3050	1174	93	ubiquitin	ubiquitin	NOUN
fnp-3050	1174	94	in	in	ADP
fnp-3050	1174	95	normal	normal	ADJ
fnp-3050	1174	96	aging	aging	NOUN
fnp-3050	1174	97	and	and	CCONJ
fnp-3050	1174	98	lewy	lewy	ADJ
fnp-3050	1174	99	body	body	NOUN
fnp-3050	1174	100	disease	disease	NOUN
fnp-3050	1174	101	.	.	PUNCT
fnp-3050	1175	1	autophagy	autophagy	ADJ
fnp-3050	1175	2	14:1404	14:1404	NUM
fnp-3050	1175	3	-	-	SYM
fnp-3050	1175	4	1418	1418	NUM
fnp-3050	1175	5	317	317	NUM
fnp-3050	1175	6	.	.	PUNCT
fnp-3050	1176	1	koper	koper	PROPN
fnp-3050	1176	2	mj	mj	PROPN
fnp-3050	1176	3	,	,	PUNCT
fnp-3050	1176	4	van	van	PROPN
fnp-3050	1176	5	schoor	schoor	PROPN
fnp-3050	1176	6	e	e	PROPN
fnp-3050	1176	7	,	,	PUNCT
fnp-3050	1176	8	ospitalieri	ospitalieri	PROPN
fnp-3050	1176	9	s	s	PROPN
fnp-3050	1176	10	,	,	PUNCT
fnp-3050	1176	11	vandenberghe	vandenberghe	ADJ
fnp-3050	1176	12	r	r	PROPN
fnp-3050	1176	13	,	,	PUNCT
fnp-3050	1176	14	vandenbulcke	vandenbulcke	PROPN
fnp-3050	1176	15	m	m	PROPN
fnp-3050	1176	16	,	,	PUNCT
fnp-3050	1176	17	von	von	PROPN
fnp-3050	1176	18	arnim	arnim	PROPN
fnp-3050	1176	19	caf	caf	PROPN
fnp-3050	1176	20	,	,	PUNCT
fnp-3050	1176	21	tousseyn	tousseyn	PROPN
fnp-3050	1176	22	t	t	PROPN
fnp-3050	1176	23	,	,	PUNCT
fnp-3050	1176	24	balusu	balusu	PROPN
fnp-3050	1176	25	s	s	PROPN
fnp-3050	1176	26	,	,	PUNCT
fnp-3050	1176	27	de	de	X
fnp-3050	1176	28	strooper	strooper	NOUN
fnp-3050	1176	29	b	b	PROPN
fnp-3050	1176	30	,	,	PUNCT
fnp-3050	1176	31	thal	thal	PROPN
fnp-3050	1176	32	dr	dr	PROPN
fnp-3050	1176	33	(	(	PUNCT
fnp-3050	1176	34	2020	2020	NUM
fnp-3050	1176	35	)	)	PUNCT
fnp-3050	1176	36	necrosome	necrosome	ADJ
fnp-3050	1176	37	complex	complex	NOUN
fnp-3050	1176	38	detected	detect	VERB
fnp-3050	1176	39	in	in	ADP
fnp-3050	1176	40	granulovacuolar	granulovacuolar	ADJ
fnp-3050	1176	41	degeneration	degeneration	NOUN
fnp-3050	1176	42	is	be	AUX
fnp-3050	1176	43	associated	associate	VERB
fnp-3050	1176	44	with	with	ADP
fnp-3050	1176	45	neuronal	neuronal	ADJ
fnp-3050	1176	46	loss	loss	NOUN
fnp-3050	1176	47	in	in	ADP
fnp-3050	1176	48	alzheimer	alzheimer	PROPN
fnp-3050	1176	49	's	's	PART
fnp-3050	1176	50	disease	disease	NOUN
fnp-3050	1176	51	.	.	PUNCT
fnp-3050	1177	1	acta	acta	PROPN
fnp-3050	1177	2	neuropathol	neuropathol	PROPN
fnp-3050	1177	3	139:463	139:463	PROPN
fnp-3050	1177	4	-	-	PUNCT
fnp-3050	1177	5	484	484	NUM
fnp-3050	1177	6	318	318	NUM
fnp-3050	1177	7	.	.	PUNCT
fnp-3050	1178	1	white	white	PROPN
fnp-3050	1178	2	lr	lr	PROPN
fnp-3050	1178	3	,	,	PUNCT
fnp-3050	1178	4	edland	edland	NOUN
fnp-3050	1178	5	sd	sd	NOUN
fnp-3050	1178	6	,	,	PUNCT
fnp-3050	1178	7	hemmy	hemmy	ADJ
fnp-3050	1178	8	ls	ls	ADJ
fnp-3050	1178	9	,	,	PUNCT
fnp-3050	1178	10	montine	montine	ADJ
fnp-3050	1178	11	ks	k	NOUN
fnp-3050	1178	12	,	,	PUNCT
fnp-3050	1178	13	zarow	zarow	VERB
fnp-3050	1178	14	c	c	PROPN
fnp-3050	1178	15	,	,	PUNCT
fnp-3050	1178	16	sonnen	sonnen	PROPN
fnp-3050	1178	17	ja	ja	PROPN
fnp-3050	1178	18	,	,	PUNCT
fnp-3050	1178	19	uyehara	uyehara	PROPN
fnp-3050	1178	20	-	-	PUNCT
fnp-3050	1178	21	lock	lock	PROPN
fnp-3050	1178	22	jh	jh	PROPN
fnp-3050	1178	23	,	,	PUNCT
fnp-3050	1178	24	gelber	gelber	PROPN
fnp-3050	1178	25	rp	rp	PROPN
fnp-3050	1178	26	,	,	PUNCT
fnp-3050	1178	27	ross	ross	PROPN
fnp-3050	1178	28	gw	gw	PROPN
fnp-3050	1178	29	,	,	PUNCT
fnp-3050	1178	30	petrovitch	petrovitch	VERB
fnp-3050	1178	31	h	h	NOUN
fnp-3050	1178	32	,	,	PUNCT
fnp-3050	1178	33	masaki	masaki	PROPN
fnp-3050	1178	34	kh	kh	PROPN
fnp-3050	1178	35	,	,	PUNCT
fnp-3050	1178	36	lim	lim	PROPN
fnp-3050	1178	37	ko	ko	PROPN
fnp-3050	1178	38	,	,	PUNCT
fnp-3050	1178	39	launer	launer	NOUN
fnp-3050	1178	40	lj	lj	PROPN
fnp-3050	1178	41	,	,	PUNCT
fnp-3050	1178	42	montine	montine	PROPN
fnp-3050	1178	43	tj	tj	PROPN
fnp-3050	1178	44	(	(	PUNCT
fnp-3050	1178	45	2016	2016	NUM
fnp-3050	1178	46	)	)	PUNCT
fnp-3050	1178	47	neuropathologic	neuropathologic	ADJ
fnp-3050	1178	48	comorbidity	comorbidity	NOUN
fnp-3050	1178	49	and	and	CCONJ
fnp-3050	1178	50	cognitive	cognitive	ADJ
fnp-3050	1178	51	impairment	impairment	NOUN
fnp-3050	1178	52	in	in	ADP
fnp-3050	1178	53	the	the	DET
fnp-3050	1178	54	nun	nun	NOUN
fnp-3050	1178	55	and	and	CCONJ
fnp-3050	1178	56	honolulu	honolulu	PROPN
fnp-3050	1178	57	-	-	PUNCT
fnp-3050	1178	58	asia	asia	PROPN
fnp-3050	1178	59	aging	age	VERB
fnp-3050	1178	60	studies	study	NOUN
fnp-3050	1178	61	.	.	PUNCT
fnp-3050	1179	1	neurology	neurology	NOUN
fnp-3050	1179	2	86:1000	86:1000	NUM
fnp-3050	1179	3	-	-	SYM
fnp-3050	1179	4	1008	1008	NUM
fnp-3050	1179	5	319	319	NUM
fnp-3050	1179	6	.	.	PUNCT
fnp-3050	1180	1	jack	jack	PROPN
fnp-3050	1180	2	cr	cr	PROPN
fnp-3050	1180	3	,	,	PUNCT
fnp-3050	1180	4	jr	jr	PROPN
fnp-3050	1180	5	.	.	PROPN
fnp-3050	1180	6	,	,	PUNCT
fnp-3050	1180	7	bennett	bennett	PROPN
fnp-3050	1180	8	da	da	PROPN
fnp-3050	1180	9	,	,	PUNCT
fnp-3050	1180	10	blennow	blennow	ADV
fnp-3050	1180	11	k	k	PROPN
fnp-3050	1180	12	,	,	PUNCT
fnp-3050	1180	13	carrillo	carrillo	PROPN
fnp-3050	1180	14	mc	mc	PROPN
fnp-3050	1180	15	,	,	PUNCT
fnp-3050	1180	16	dunn	dunn	PROPN
fnp-3050	1180	17	b	b	PROPN
fnp-3050	1180	18	,	,	PUNCT
fnp-3050	1180	19	haeberlein	haeberlein	PROPN
fnp-3050	1180	20	sb	sb	PROPN
fnp-3050	1180	21	,	,	PUNCT
fnp-3050	1180	22	holtzman	holtzman	PROPN
fnp-3050	1180	23	dm	dm	PROPN
fnp-3050	1180	24	,	,	PUNCT
fnp-3050	1180	25	jagust	jagust	PROPN
fnp-3050	1180	26	w	w	PROPN
fnp-3050	1180	27	,	,	PUNCT
fnp-3050	1180	28	jessen	jessen	PROPN
fnp-3050	1180	29	f	f	PROPN
fnp-3050	1180	30	,	,	PUNCT
fnp-3050	1180	31	karlawish	karlawish	PROPN
fnp-3050	1180	32	j	j	PROPN
fnp-3050	1180	33	,	,	PUNCT
fnp-3050	1180	34	liu	liu	PROPN
fnp-3050	1180	35	e	e	PROPN
fnp-3050	1180	36	,	,	PUNCT
fnp-3050	1180	37	molinuevo	molinuevo	PROPN
fnp-3050	1180	38	jl	jl	PROPN
fnp-3050	1180	39	,	,	PUNCT
fnp-3050	1180	40	montine	montine	PROPN
fnp-3050	1180	41	t	t	PROPN
fnp-3050	1180	42	,	,	PUNCT
fnp-3050	1180	43	phelps	phelps	PROPN
fnp-3050	1180	44	c	c	PROPN
fnp-3050	1180	45	,	,	PUNCT
fnp-3050	1180	46	rankin	rankin	PROPN
fnp-3050	1180	47	kp	kp	PROPN
fnp-3050	1180	48	,	,	PUNCT
fnp-3050	1180	49	rowe	rowe	PROPN
fnp-3050	1180	50	cc	cc	PROPN
fnp-3050	1180	51	,	,	PUNCT
fnp-3050	1180	52	scheltens	schelten	VERB
fnp-3050	1180	53	p	p	NOUN
fnp-3050	1180	54	,	,	PUNCT
fnp-3050	1180	55	siemers	siemer	NOUN
fnp-3050	1180	56	e	e	NOUN
fnp-3050	1180	57	,	,	PUNCT
fnp-3050	1180	58	snyder	snyder	PROPN
fnp-3050	1180	59	hm	hm	PROPN
fnp-3050	1180	60	,	,	PUNCT
fnp-3050	1180	61	sperling	sperling	PROPN
fnp-3050	1180	62	r	r	PROPN
fnp-3050	1180	63	(	(	PUNCT
fnp-3050	1180	64	2018	2018	NUM
fnp-3050	1180	65	)	)	PUNCT
fnp-3050	1180	66	nia	nia	PROPN
fnp-3050	1180	67	-	-	PUNCT
fnp-3050	1180	68	aa	aa	PROPN
fnp-3050	1180	69	research	research	NOUN
fnp-3050	1180	70	framework	framework	NOUN
fnp-3050	1180	71	:	:	PUNCT
fnp-3050	1180	72	toward	toward	ADP
fnp-3050	1180	73	a	a	DET
fnp-3050	1180	74	biological	biological	ADJ
fnp-3050	1180	75	definition	definition	NOUN
fnp-3050	1180	76	of	of	ADP
fnp-3050	1180	77	alzheimer	alzheimer	PROPN
fnp-3050	1180	78	's	's	PART
fnp-3050	1180	79	disease	disease	NOUN
fnp-3050	1180	80	.	.	PUNCT
fnp-3050	1181	1	alzheimers	alzheimers	PROPN
fnp-3050	1181	2	dement	dement	PROPN
fnp-3050	1181	3	14:535	14:535	PROPN
fnp-3050	1181	4	-	-	PUNCT
fnp-3050	1181	5	562	562	NUM
fnp-3050	1181	6	320	320	NUM
fnp-3050	1181	7	.	.	PUNCT
fnp-3050	1182	1	nelson	nelson	PROPN
fnp-3050	1182	2	pt	pt	PROPN
fnp-3050	1182	3	,	,	PUNCT
fnp-3050	1182	4	trojanowski	trojanowski	PROPN
fnp-3050	1182	5	jq	jq	PROPN
fnp-3050	1182	6	,	,	PUNCT
fnp-3050	1182	7	abner	abner	PROPN
fnp-3050	1182	8	el	el	PROPN
fnp-3050	1182	9	,	,	PUNCT
fnp-3050	1182	10	al	al	PROPN
fnp-3050	1182	11	-	-	PUNCT
fnp-3050	1182	12	janabi	janabi	NOUN
fnp-3050	1182	13	om	om	NOUN
fnp-3050	1182	14	,	,	PUNCT
fnp-3050	1182	15	jicha	jicha	PROPN
fnp-3050	1182	16	ga	ga	PROPN
fnp-3050	1182	17	,	,	PUNCT
fnp-3050	1182	18	schmitt	schmitt	PROPN
fnp-3050	1182	19	fa	fa	PROPN
fnp-3050	1182	20	,	,	PUNCT
fnp-3050	1182	21	smith	smith	PROPN
fnp-3050	1182	22	cd	cd	PROPN
fnp-3050	1182	23	,	,	PUNCT
fnp-3050	1182	24	fardo	fardo	PROPN
fnp-3050	1182	25	dw	dw	PROPN
fnp-3050	1182	26	,	,	PUNCT
fnp-3050	1182	27	wang	wang	PROPN
fnp-3050	1182	28	wx	wx	PROPN
fnp-3050	1182	29	,	,	PUNCT
fnp-3050	1182	30	kryscio	kryscio	PROPN
fnp-3050	1182	31	rj	rj	PROPN
fnp-3050	1182	32	,	,	PUNCT
fnp-3050	1182	33	neltner	neltner	PROPN
fnp-3050	1182	34	jh	jh	PROPN
fnp-3050	1182	35	,	,	PUNCT
fnp-3050	1182	36	kukull	kukull	PROPN
fnp-3050	1182	37	wa	wa	PROPN
fnp-3050	1182	38	,	,	PUNCT
fnp-3050	1182	39	cykowski	cykowski	PROPN
fnp-3050	1182	40	md	md	PROPN
fnp-3050	1182	41	,	,	PUNCT
fnp-3050	1182	42	van	van	PROPN
fnp-3050	1182	43	eldik	eldik	X
fnp-3050	1182	44	lj	lj	PROPN
fnp-3050	1182	45	,	,	PUNCT
fnp-3050	1182	46	ighodaro	ighodaro	VERB
fnp-3050	1182	47	et	et	PROPN
fnp-3050	1182	48	(	(	PUNCT
fnp-3050	1182	49	2016	2016	NUM
fnp-3050	1182	50	)	)	PUNCT
fnp-3050	1182	51	"	"	PUNCT
fnp-3050	1182	52	new	new	ADJ
fnp-3050	1182	53	old	old	ADJ
fnp-3050	1182	54	pathologies	pathology	NOUN
fnp-3050	1182	55	"	"	PUNCT
fnp-3050	1182	56	:	:	PUNCT
fnp-3050	1182	57	ad	ad	NOUN
fnp-3050	1182	58	,	,	PUNCT
fnp-3050	1182	59	part	part	NOUN
fnp-3050	1182	60	,	,	PUNCT
fnp-3050	1182	61	and	and	CCONJ
fnp-3050	1182	62	cerebral	cerebral	ADJ
fnp-3050	1182	63	age	age	NOUN
fnp-3050	1182	64	-	-	PUNCT
fnp-3050	1182	65	related	relate	VERB
fnp-3050	1182	66	tdp-43	tdp-43	NOUN
fnp-3050	1182	67	with	with	ADP
fnp-3050	1182	68	sclerosis	sclerosis	NOUN
fnp-3050	1182	69	(	(	PUNCT
fnp-3050	1182	70	carts	cart	NOUN
fnp-3050	1182	71	)	)	PUNCT
fnp-3050	1182	72	.	.	PUNCT
fnp-3050	1183	1	j	j	PROPN
fnp-3050	1183	2	neuropathol	neuropathol	PROPN
fnp-3050	1183	3	exp	exp	PROPN
fnp-3050	1183	4	neurol	neurol	PROPN
fnp-3050	1183	5	75:482	75:482	PROPN
fnp-3050	1183	6	-	-	PUNCT
fnp-3050	1183	7	498	498	NUM
fnp-3050	1183	8	321	321	NUM
fnp-3050	1183	9	.	.	PUNCT
fnp-3050	1184	1	ricci	ricci	PROPN
fnp-3050	1184	2	m	m	PROPN
fnp-3050	1184	3	,	,	PUNCT
fnp-3050	1184	4	cimini	cimini	PROPN
fnp-3050	1184	5	a	a	PROPN
fnp-3050	1184	6	,	,	PUNCT
fnp-3050	1184	7	chiaravalloti	chiaravalloti	NOUN
fnp-3050	1184	8	a	a	PRON
fnp-3050	1184	9	,	,	PUNCT
fnp-3050	1184	10	filippi	filippi	PROPN
fnp-3050	1184	11	l	l	PROPN
fnp-3050	1184	12	,	,	PUNCT
fnp-3050	1184	13	schillaci	schillaci	NOUN
fnp-3050	1184	14	o	o	X
fnp-3050	1184	15	(	(	PUNCT
fnp-3050	1184	16	2020	2020	NUM
fnp-3050	1184	17	)	)	PUNCT
fnp-3050	1184	18	positron	positron	NOUN
fnp-3050	1184	19	emission	emission	NOUN
fnp-3050	1184	20	tomography	tomography	NOUN
fnp-3050	1184	21	(	(	PUNCT
fnp-3050	1184	22	pet	pet	NOUN
fnp-3050	1184	23	)	)	PUNCT
fnp-3050	1184	24	and	and	CCONJ
fnp-3050	1184	25	neuroimaging	neuroimage	VERB
fnp-3050	1184	26	in	in	ADP
fnp-3050	1184	27	the	the	DET
fnp-3050	1184	28	personalized	personalized	ADJ
fnp-3050	1184	29	approach	approach	NOUN
fnp-3050	1184	30	to	to	ADP
fnp-3050	1184	31	neurodegenerative	neurodegenerative	ADJ
fnp-3050	1184	32	causes	cause	NOUN
fnp-3050	1184	33	of	of	ADP
fnp-3050	1184	34	dementia	dementia	NOUN
fnp-3050	1184	35	.	.	PUNCT
fnp-3050	1185	1	int	int	PROPN
fnp-3050	1185	2	j	j	PROPN
fnp-3050	1185	3	mol	mol	ADP
fnp-3050	1185	4	sci	sci	PROPN
fnp-3050	1185	5	21:7481	21:7481	NUM
fnp-3050	1185	6	322	322	NUM
fnp-3050	1185	7	.	.	PUNCT
fnp-3050	1186	1	koychev	koychev	PROPN
fnp-3050	1186	2	i	i	PROPN
fnp-3050	1186	3	,	,	PUNCT
fnp-3050	1186	4	hofer	hofer	PROPN
fnp-3050	1186	5	m	m	PROPN
fnp-3050	1186	6	,	,	PUNCT
fnp-3050	1186	7	friedman	friedman	PROPN
fnp-3050	1186	8	n	n	CCONJ
fnp-3050	1186	9	(	(	PUNCT
fnp-3050	1186	10	2020	2020	NUM
fnp-3050	1186	11	)	)	PUNCT
fnp-3050	1186	12	correlation	correlation	NOUN
fnp-3050	1186	13	of	of	ADP
fnp-3050	1186	14	alzheimer	alzheimer	PROPN
fnp-3050	1186	15	disease	disease	PROPN
fnp-3050	1186	16	neuropathologic	neuropathologic	NOUN
fnp-3050	1186	17	staging	staging	NOUN
fnp-3050	1186	18	with	with	ADP
fnp-3050	1186	19	amyloid	amyloid	NOUN
fnp-3050	1186	20	and	and	CCONJ
fnp-3050	1186	21	tau	tau	PROPN
fnp-3050	1186	22	scintigraphic	scintigraphic	ADJ
fnp-3050	1186	23	imaging	imaging	NOUN
fnp-3050	1186	24	biomarkers	biomarker	NOUN
fnp-3050	1186	25	.	.	PUNCT
fnp-3050	1187	1	j	j	PROPN
fnp-3050	1187	2	nucl	nucl	PROPN
fnp-3050	1187	3	med	med	PROPN
fnp-3050	1187	4	61:1413	61:1413	NUM
fnp-3050	1187	5	-	-	SYM
fnp-3050	1187	6	1418	1418	NUM
fnp-3050	1187	7	copyright	copyright	NOUN
fnp-3050	1187	8	:	:	PUNCT
fnp-3050	1188	1	©	©	PROPN
fnp-3050	1188	2	2020	2020	NUM
fnp-3050	1188	3	the	the	DET
fnp-3050	1188	4	author(s	author(s	NOUN
fnp-3050	1188	5	)	)	PUNCT
fnp-3050	1188	6	.	.	PUNCT
fnp-3050	1189	1	this	this	PRON
fnp-3050	1189	2	is	be	AUX
fnp-3050	1189	3	an	an	DET
fnp-3050	1189	4	open	open	ADJ
fnp-3050	1189	5	access	access	NOUN
fnp-3050	1189	6	article	article	NOUN
fnp-3050	1189	7	distributed	distribute	VERB
fnp-3050	1189	8	under	under	ADP
fnp-3050	1189	9	the	the	DET
fnp-3050	1189	10	terms	term	NOUN
fnp-3050	1189	11	of	of	ADP
fnp-3050	1189	12	the	the	DET
fnp-3050	1189	13	creative	creative	ADJ
fnp-3050	1189	14	commons	common	NOUN
fnp-3050	1189	15	attribution	attribution	NOUN
fnp-3050	1189	16	4.0	4.0	NUM
fnp-3050	1189	17	international	international	ADJ
fnp-3050	1189	18	license	license	NOUN
fnp-3050	1189	19	(	(	PUNCT
fnp-3050	1189	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3050	1189	21	)	)	PUNCT
fnp-3050	1189	22	,	,	PUNCT
fnp-3050	1189	23	which	which	PRON
fnp-3050	1189	24	permits	permit	VERB
fnp-3050	1189	25	unrestricted	unrestricted	ADJ
fnp-3050	1189	26	use	use	NOUN
fnp-3050	1189	27	,	,	PUNCT
fnp-3050	1189	28	distribution	distribution	NOUN
fnp-3050	1189	29	,	,	PUNCT
fnp-3050	1189	30	and	and	CCONJ
fnp-3050	1189	31	reproduction	reproduction	NOUN
fnp-3050	1189	32	in	in	ADP
fnp-3050	1189	33	any	any	DET
fnp-3050	1189	34	medium	medium	NOUN
fnp-3050	1189	35	,	,	PUNCT
fnp-3050	1189	36	provided	provide	VERB
fnp-3050	1189	37	the	the	DET
fnp-3050	1189	38	original	original	ADJ
fnp-3050	1189	39	author	author	NOUN
fnp-3050	1189	40	and	and	CCONJ
fnp-3050	1189	41	source	source	NOUN
fnp-3050	1189	42	are	be	AUX
fnp-3050	1189	43	credited	credit	VERB
fnp-3050	1189	44	,	,	PUNCT
fnp-3050	1189	45	a	a	DET
fnp-3050	1189	46	link	link	NOUN
fnp-3050	1189	47	to	to	ADP
fnp-3050	1189	48	the	the	DET
fnp-3050	1189	49	creative	creative	ADJ
fnp-3050	1189	50	commons	common	NOUN
fnp-3050	1189	51	license	license	NOUN
fnp-3050	1189	52	is	be	AUX
fnp-3050	1189	53	provided	provide	VERB
fnp-3050	1189	54	,	,	PUNCT
fnp-3050	1189	55	and	and	CCONJ
fnp-3050	1189	56	any	any	DET
fnp-3050	1189	57	changes	change	NOUN
fnp-3050	1189	58	are	be	AUX
fnp-3050	1189	59	indicated	indicate	VERB
fnp-3050	1189	60	.	.	PUNCT
fnp-3050	1190	1	the	the	DET
fnp-3050	1190	2	creative	creative	ADJ
fnp-3050	1190	3	commons	common	NOUN
fnp-3050	1190	4	public	public	ADJ
fnp-3050	1190	5	domain	domain	NOUN
fnp-3050	1190	6	dedication	dedication	NOUN
fnp-3050	1190	7	waiver	waiver	NOUN
fnp-3050	1190	8	(	(	PUNCT
fnp-3050	1190	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3050	1190	10	)	)	PUNCT
fnp-3050	1190	11	applies	apply	VERB
fnp-3050	1190	12	to	to	ADP
fnp-3050	1190	13	the	the	DET
fnp-3050	1190	14	data	datum	NOUN
fnp-3050	1190	15	made	make	VERB
fnp-3050	1190	16	available	available	ADJ
fnp-3050	1190	17	in	in	ADP
fnp-3050	1190	18	this	this	DET
fnp-3050	1190	19	article	article	NOUN
fnp-3050	1190	20	,	,	PUNCT
fnp-3050	1190	21	unless	unless	SCONJ
fnp-3050	1190	22	otherwise	otherwise	ADV
fnp-3050	1190	23	stated	state	VERB
fnp-3050	1190	24	.	.	PUNCT