id	sid	tid	token	lemma	pos
fnp-3271	1	1	neurooncology	neurooncology	NOUN
fnp-3271	1	2	:	:	PUNCT
fnp-3271	1	3	2021	2021	NUM
fnp-3271	1	4	update	update	NOUN
fnp-3271	1	5	feel	feel	VERB
fnp-3271	1	6	free	free	ADJ
fnp-3271	1	7	to	to	PART
fnp-3271	1	8	add	add	VERB
fnp-3271	1	9	comments	comment	NOUN
fnp-3271	1	10	by	by	ADP
fnp-3271	1	11	clicking	click	VERB
fnp-3271	1	12	these	these	DET
fnp-3271	1	13	icons	icon	NOUN
fnp-3271	1	14	on	on	ADP
fnp-3271	1	15	the	the	DET
fnp-3271	1	16	sidebar	sidebar	NOUN
fnp-3271	1	17	free	free	ADJ
fnp-3271	1	18	neuropathology	neuropathology	NOUN
fnp-3271	1	19	2:5	2:5	NUM
fnp-3271	1	20	(	(	PUNCT
fnp-3271	1	21	2021	2021	NUM
fnp-3271	1	22	)	)	PUNCT
fnp-3271	1	23	review	review	VERB
fnp-3271	1	24	neurooncology	neurooncology	NOUN
fnp-3271	1	25	:	:	PUNCT
fnp-3271	1	26	2021	2021	NUM
fnp-3271	1	27	update	update	NOUN
fnp-3271	1	28	pieter	pieter	NOUN
fnp-3271	1	29	wesseling1,2	wesseling1,2	PROPN
fnp-3271	1	30	1	1	NUM
fnp-3271	1	31	department	department	NOUN
fnp-3271	1	32	of	of	ADP
fnp-3271	1	33	pathology	pathology	PROPN
fnp-3271	1	34	,	,	PUNCT
fnp-3271	1	35	amsterdam	amsterdam	PROPN
fnp-3271	1	36	university	university	PROPN
fnp-3271	1	37	medical	medical	ADJ
fnp-3271	1	38	centers	center	NOUN
fnp-3271	1	39	,	,	PUNCT
fnp-3271	1	40	location	location	NOUN
fnp-3271	1	41	vumc	vumc	NOUN
fnp-3271	1	42	,	,	PUNCT
fnp-3271	1	43	brain	brain	NOUN
fnp-3271	1	44	tumor	tumor	PROPN
fnp-3271	1	45	center	center	PROPN
fnp-3271	1	46	am	am	NOUN
fnp-3271	1	47	-	-	PUNCT
fnp-3271	1	48	sterdam	sterdam	NOUN
fnp-3271	1	49	,	,	PUNCT
fnp-3271	1	50	amsterdam	amsterdam	PROPN
fnp-3271	1	51	,	,	PUNCT
fnp-3271	1	52	the	the	DET
fnp-3271	1	53	netherlands	netherlands	PROPN
fnp-3271	1	54	2	2	NUM
fnp-3271	1	55	laboratory	laboratory	NOUN
fnp-3271	1	56	for	for	ADP
fnp-3271	1	57	childhood	childhood	NOUN
fnp-3271	1	58	cancer	cancer	NOUN
fnp-3271	1	59	pathology	pathology	NOUN
fnp-3271	1	60	,	,	PUNCT
fnp-3271	1	61	princess	princess	NOUN
fnp-3271	1	62	máxima	máxima	PROPN
fnp-3271	1	63	center	center	PROPN
fnp-3271	1	64	for	for	ADP
fnp-3271	1	65	pediatric	pediatric	ADJ
fnp-3271	1	66	oncology	oncology	NOUN
fnp-3271	1	67	,	,	PUNCT
fnp-3271	1	68	utrecht	utrecht	PROPN
fnp-3271	1	69	,	,	PUNCT
fnp-3271	1	70	the	the	DET
fnp-3271	1	71	netherlands	netherlands	PROPN
fnp-3271	1	72	corresponding	corresponding	ADJ
fnp-3271	1	73	author	author	NOUN
fnp-3271	1	74	:	:	PUNCT
fnp-3271	1	75	pieter	pieter	NOUN
fnp-3271	1	76	wesseling	wesseling	PROPN
fnp-3271	1	77	,	,	PUNCT
fnp-3271	1	78	md	md	PROPN
fnp-3271	1	79	,	,	PUNCT
fnp-3271	1	80	phd	phd	NOUN
fnp-3271	1	81	·	·	PUNCT
fnp-3271	1	82	department	department	NOUN
fnp-3271	1	83	of	of	ADP
fnp-3271	1	84	pathology	pathology	PROPN
fnp-3271	1	85	·	·	PUNCT
fnp-3271	1	86	amsterdam	amsterdam	PROPN
fnp-3271	1	87	university	university	PROPN
fnp-3271	1	88	medical	medical	ADJ
fnp-3271	1	89	centers	center	NOUN
fnp-3271	1	90	/	/	SYM
fnp-3271	1	91	vumc	vumc	NOUN
fnp-3271	1	92	·	·	PUNCT
fnp-3271	1	93	de	de	X
fnp-3271	1	94	boelelaan	boelelaan	NOUN
fnp-3271	1	95	1117	1117	NUM
fnp-3271	1	96	·	·	SYM
fnp-3271	1	97	1081	1081	NUM
fnp-3271	1	98	hv	hv	PROPN
fnp-3271	1	99	amsterdam	amsterdam	PROPN
fnp-3271	1	100	·	·	PUNCT
fnp-3271	1	101	the	the	DET
fnp-3271	1	102	netherlands	netherlands	PROPN
fnp-3271	1	103	p.wesseling@amsterdamumc.nl	p.wesseling@amsterdamumc.nl	VERB
fnp-3271	1	104	submitted	submit	VERB
fnp-3271	1	105	:	:	PUNCT
fnp-3271	1	106	26	26	NUM
fnp-3271	1	107	february	february	NOUN
fnp-3271	1	108	2021	2021	NUM
fnp-3271	1	109	accepted	accept	VERB
fnp-3271	1	110	:	:	PUNCT
fnp-3271	1	111	09	09	NUM
fnp-3271	1	112	march	march	NOUN
fnp-3271	1	113	2021	2021	NUM
fnp-3271	1	114	copyedited	copyedit	VERB
fnp-3271	1	115	by	by	ADP
fnp-3271	1	116	:	:	PUNCT
fnp-3271	1	117	deanna	deanna	PROPN
fnp-3271	1	118	fang	fang	PROPN
fnp-3271	1	119	published	publish	VERB
fnp-3271	1	120	:	:	PUNCT
fnp-3271	1	121	17	17	NUM
fnp-3271	1	122	march	march	NOUN
fnp-3271	1	123	2021	2021	NUM
fnp-3271	1	124	https://doi.org/10.17879/freeneuropathology-2021-3271	https://doi.org/10.17879/freeneuropathology-2021-3271	ADP
fnp-3271	1	125	keywords	keyword	NOUN
fnp-3271	1	126	:	:	PUNCT
fnp-3271	1	127	brain	brain	NOUN
fnp-3271	1	128	tumor	tumor	NOUN
fnp-3271	1	129	,	,	PUNCT
fnp-3271	1	130	molecular	molecular	ADJ
fnp-3271	1	131	diagnostics	diagnostic	NOUN
fnp-3271	1	132	,	,	PUNCT
fnp-3271	1	133	glioma	glioma	NOUN
fnp-3271	1	134	,	,	PUNCT
fnp-3271	1	135	medulloblastoma	medulloblastoma	NOUN
fnp-3271	1	136	,	,	PUNCT
fnp-3271	1	137	tumor	tumor	NOUN
fnp-3271	1	138	microenvironment	microenvironment	NOUN
fnp-3271	1	139	,	,	PUNCT
fnp-3271	1	140	covid-19	covid-19	PROPN
fnp-3271	1	141	abstract	abstract	ADV
fnp-3271	1	142	this	this	DET
fnp-3271	1	143	article	article	NOUN
fnp-3271	1	144	briefly	briefly	ADV
fnp-3271	1	145	presents	present	VERB
fnp-3271	1	146	10	10	NUM
fnp-3271	1	147	topics	topic	NOUN
fnp-3271	1	148	that	that	PRON
fnp-3271	1	149	were	be	AUX
fnp-3271	1	150	selected	select	VERB
fnp-3271	1	151	by	by	ADP
fnp-3271	1	152	the	the	DET
fnp-3271	1	153	author	author	NOUN
fnp-3271	1	154	as	as	ADP
fnp-3271	1	155	‘	'	PUNCT
fnp-3271	1	156	top	top	ADJ
fnp-3271	1	157	10	10	NUM
fnp-3271	1	158	discoveries	discovery	NOUN
fnp-3271	1	159	’	'	PUNCT
fnp-3271	1	160	published	publish	VERB
fnp-3271	1	161	in	in	ADP
fnp-3271	1	162	2020	2020	NUM
fnp-3271	1	163	in	in	ADP
fnp-3271	1	164	the	the	DET
fnp-3271	1	165	broader	broad	ADJ
fnp-3271	1	166	field	field	NOUN
fnp-3271	1	167	of	of	ADP
fnp-3271	1	168	neurooncological	neurooncological	ADJ
fnp-3271	1	169	pathology	pathology	NOUN
fnp-3271	1	170	including	include	VERB
fnp-3271	1	171	neurosciences	neuroscience	NOUN
fnp-3271	1	172	as	as	ADV
fnp-3271	1	173	well	well	ADV
fnp-3271	1	174	as	as	ADP
fnp-3271	1	175	clinical	clinical	ADJ
fnp-3271	1	176	neurooncology	neurooncology	NOUN
fnp-3271	1	177	of	of	ADP
fnp-3271	1	178	interest	interest	NOUN
fnp-3271	1	179	for	for	ADP
fnp-3271	1	180	neurooncological	neurooncological	ADJ
fnp-3271	1	181	pathology	pathology	NOUN
fnp-3271	1	182	.	.	PUNCT
fnp-3271	2	1	the	the	DET
fnp-3271	2	2	selected	select	VERB
fnp-3271	2	3	topics	topic	NOUN
fnp-3271	2	4	concern	concern	NOUN
fnp-3271	2	5	new	new	ADJ
fnp-3271	2	6	information	information	NOUN
fnp-3271	2	7	on	on	ADP
fnp-3271	2	8	the	the	DET
fnp-3271	2	9	molecular	molecular	ADJ
fnp-3271	2	10	characteristics	characteristic	NOUN
fnp-3271	2	11	of	of	ADP
fnp-3271	2	12	gliomas	glioma	NOUN
fnp-3271	2	13	(	(	PUNCT
fnp-3271	2	14	infratentorial	infratentorial	ADJ
fnp-3271	2	15	idh	idh	NOUN
fnp-3271	2	16	-	-	PUNCT
fnp-3271	2	17	mutant	mutant	NOUN
fnp-3271	2	18	diffuse	diffuse	NOUN
fnp-3271	2	19	astrocytomas	astrocytoma	NOUN
fnp-3271	2	20	,	,	PUNCT
fnp-3271	2	21	pediatric	pediatric	ADJ
fnp-3271	2	22	low	low	ADJ
fnp-3271	2	23	-	-	PUNCT
fnp-3271	2	24	grade	grade	NOUN
fnp-3271	2	25	gliomas	glioma	NOUN
fnp-3271	2	26	,	,	PUNCT
fnp-3271	2	27	infant	infant	NOUN
fnp-3271	2	28	-	-	PUNCT
fnp-3271	2	29	type	type	NOUN
fnp-3271	2	30	high	high	ADJ
fnp-3271	2	31	-	-	PUNCT
fnp-3271	2	32	grade	grade	NOUN
fnp-3271	2	33	gliomas	glioma	NOUN
fnp-3271	2	34	,	,	PUNCT
fnp-3271	2	35	hypermutation	hypermutation	NOUN
fnp-3271	2	36	in	in	ADP
fnp-3271	2	37	gliomas	glioma	NOUN
fnp-3271	2	38	)	)	PUNCT
fnp-3271	2	39	,	,	PUNCT
fnp-3271	2	40	the	the	DET
fnp-3271	2	41	immunological	immunological	ADJ
fnp-3271	2	42	aspects	aspect	NOUN
fnp-3271	2	43	of	of	ADP
fnp-3271	2	44	the	the	DET
fnp-3271	2	45	brain	brain	NOUN
fnp-3271	2	46	tumor	tumor	NOUN
fnp-3271	2	47	microenvironment	microenvironment	NOUN
fnp-3271	2	48	(	(	PUNCT
fnp-3271	2	49	tme	tme	PROPN
fnp-3271	2	50	)	)	PUNCT
fnp-3271	2	51	,	,	PUNCT
fnp-3271	2	52	the	the	DET
fnp-3271	2	53	impact	impact	NOUN
fnp-3271	2	54	of	of	ADP
fnp-3271	2	55	the	the	DET
fnp-3271	2	56	tme	tme	NOUN
fnp-3271	2	57	on	on	ADP
fnp-3271	2	58	preclinical	preclinical	ADJ
fnp-3271	2	59	glioma	glioma	NOUN
fnp-3271	2	60	models	model	NOUN
fnp-3271	2	61	,	,	PUNCT
fnp-3271	2	62	and	and	CCONJ
fnp-3271	2	63	the	the	DET
fnp-3271	2	64	importance	importance	NOUN
fnp-3271	2	65	of	of	ADP
fnp-3271	2	66	lymphatic	lymphatic	ADJ
fnp-3271	2	67	drainage	drainage	NOUN
fnp-3271	2	68	on	on	ADP
fnp-3271	2	69	brain	brain	NOUN
fnp-3271	2	70	tumor	tumor	NOUN
fnp-3271	2	71	surveillance	surveillance	NOUN
fnp-3271	2	72	.	.	PUNCT
fnp-3271	3	1	furthermore	furthermore	ADV
fnp-3271	3	2	,	,	PUNCT
fnp-3271	3	3	important	important	ADJ
fnp-3271	3	4	papers	paper	NOUN
fnp-3271	3	5	were	be	AUX
fnp-3271	3	6	published	publish	VERB
fnp-3271	3	7	on	on	ADP
fnp-3271	3	8	two	two	NUM
fnp-3271	3	9	‘	'	PUNCT
fnp-3271	3	10	new	new	ADJ
fnp-3271	3	11	’	'	PUNCT
fnp-3271	3	12	genetic	genetic	ADJ
fnp-3271	3	13	syndromes	syndrome	NOUN
fnp-3271	3	14	predisposing	predispose	VERB
fnp-3271	3	15	to	to	ADP
fnp-3271	3	16	medulloblastoma	medulloblastoma	ADJ
fnp-3271	3	17	,	,	PUNCT
fnp-3271	3	18	on	on	ADP
fnp-3271	3	19	liquid	liquid	ADJ
fnp-3271	3	20	biopsy	biopsy	NOUN
fnp-3271	3	21	-	-	PUNCT
fnp-3271	3	22	based	base	VERB
fnp-3271	3	23	diagnosis	diagnosis	NOUN
fnp-3271	3	24	of	of	ADP
fnp-3271	3	25	central	central	ADJ
fnp-3271	3	26	nervous	nervous	ADJ
fnp-3271	3	27	system	system	NOUN
fnp-3271	3	28	(	(	PUNCT
fnp-3271	3	29	cns	cns	NOUN
fnp-3271	3	30	)	)	PUNCT
fnp-3271	3	31	tumors	tumor	NOUN
fnp-3271	3	32	,	,	PUNCT
fnp-3271	3	33	and	and	CCONJ
fnp-3271	3	34	on	on	ADP
fnp-3271	3	35	the	the	DET
fnp-3271	3	36	‘	'	PUNCT
fnp-3271	3	37	microbiome	microbiome	NOUN
fnp-3271	3	38	’	'	PUNCT
fnp-3271	3	39	in	in	ADP
fnp-3271	3	40	glioblastomas	glioblastoma	NOUN
fnp-3271	3	41	(	(	PUNCT
fnp-3271	3	42	and	and	CCONJ
fnp-3271	3	43	other	other	ADJ
fnp-3271	3	44	cancers	cancer	NOUN
fnp-3271	3	45	)	)	PUNCT
fnp-3271	3	46	.	.	PUNCT
fnp-3271	4	1	in	in	ADP
fnp-3271	4	2	the	the	DET
fnp-3271	4	3	last	last	ADJ
fnp-3271	4	4	part	part	NOUN
fnp-3271	4	5	of	of	ADP
fnp-3271	4	6	this	this	DET
fnp-3271	4	7	review	review	NOUN
fnp-3271	4	8	,	,	PUNCT
fnp-3271	4	9	a	a	DET
fnp-3271	4	10	dozen	dozen	NOUN
fnp-3271	4	11	of	of	ADP
fnp-3271	4	12	papers	paper	NOUN
fnp-3271	4	13	are	be	AUX
fnp-3271	4	14	given	give	VERB
fnp-3271	4	15	as	as	ADP
fnp-3271	4	16	examples	example	NOUN
fnp-3271	4	17	of	of	ADP
fnp-3271	4	18	papers	paper	NOUN
fnp-3271	4	19	that	that	PRON
fnp-3271	4	20	did	do	AUX
fnp-3271	4	21	not	not	PART
fnp-3271	4	22	make	make	VERB
fnp-3271	4	23	it	it	PRON
fnp-3271	4	24	to	to	ADP
fnp-3271	4	25	the	the	DET
fnp-3271	4	26	top	top	ADJ
fnp-3271	4	27	10	10	NUM
fnp-3271	4	28	list	list	NOUN
fnp-3271	4	29	of	of	ADP
fnp-3271	4	30	the	the	DET
fnp-3271	4	31	author	author	NOUN
fnp-3271	4	32	,	,	PUNCT
fnp-3271	4	33	underscoring	underscore	VERB
fnp-3271	4	34	the	the	DET
fnp-3271	4	35	subjective	subjective	ADJ
fnp-3271	4	36	component	component	NOUN
fnp-3271	4	37	in	in	ADP
fnp-3271	4	38	the	the	DET
fnp-3271	4	39	selection	selection	NOUN
fnp-3271	4	40	process	process	NOUN
fnp-3271	4	41	.	.	PUNCT
fnp-3271	5	1	acknowledging	acknowledge	VERB
fnp-3271	5	2	that	that	SCONJ
fnp-3271	5	3	2020	2020	NUM
fnp-3271	5	4	will	will	AUX
fnp-3271	5	5	be	be	AUX
fnp-3271	5	6	remembered	remember	VERB
fnp-3271	5	7	as	as	ADP
fnp-3271	5	8	the	the	DET
fnp-3271	5	9	year	year	NOUN
fnp-3271	5	10	in	in	ADP
fnp-3271	5	11	which	which	PRON
fnp-3271	5	12	the	the	DET
fnp-3271	5	13	world	world	NOUN
fnp-3271	5	14	changed	change	VERB
fnp-3271	5	15	because	because	SCONJ
fnp-3271	5	16	of	of	ADP
fnp-3271	5	17	the	the	DET
fnp-3271	5	18	covid-19	covid-19	PROPN
fnp-3271	5	19	pandemic	pandemic	NOUN
fnp-3271	5	20	,	,	PUNCT
fnp-3271	5	21	some	some	PRON
fnp-3271	5	22	of	of	ADP
fnp-3271	5	23	the	the	DET
fnp-3271	5	24	consequences	consequence	NOUN
fnp-3271	5	25	of	of	ADP
fnp-3271	5	26	this	this	DET
fnp-3271	5	27	pandemic	pandemic	NOUN
fnp-3271	5	28	for	for	ADP
fnp-3271	5	29	neurooncological	neurooncological	ADJ
fnp-3271	5	30	pathology	pathology	NOUN
fnp-3271	5	31	are	be	AUX
fnp-3271	5	32	briefly	briefly	ADV
fnp-3271	5	33	discussed	discuss	VERB
fnp-3271	5	34	as	as	ADV
fnp-3271	5	35	well	well	ADV
fnp-3271	5	36	.	.	PUNCT
fnp-3271	6	1	hopefully	hopefully	ADV
fnp-3271	6	2	,	,	PUNCT
fnp-3271	6	3	this	this	DET
fnp-3271	6	4	review	review	NOUN
fnp-3271	6	5	forms	form	VERB
fnp-3271	6	6	an	an	DET
fnp-3271	6	7	incentive	incentive	NOUN
fnp-3271	6	8	to	to	PART
fnp-3271	6	9	appreciate	appreciate	VERB
fnp-3271	6	10	the	the	DET
fnp-3271	6	11	wealth	wealth	NOUN
fnp-3271	6	12	of	of	ADP
fnp-3271	6	13	information	information	NOUN
fnp-3271	6	14	provided	provide	VERB
fnp-3271	6	15	by	by	ADP
fnp-3271	6	16	the	the	DET
fnp-3271	6	17	papers	paper	NOUN
fnp-3271	6	18	that	that	PRON
fnp-3271	6	19	were	be	AUX
fnp-3271	6	20	used	use	VERB
fnp-3271	6	21	as	as	ADP
fnp-3271	6	22	building	build	VERB
fnp-3271	6	23	blocks	block	NOUN
fnp-3271	6	24	for	for	ADP
fnp-3271	6	25	the	the	DET
fnp-3271	6	26	present	present	ADJ
fnp-3271	6	27	manuscript	manuscript	NOUN
fnp-3271	6	28	.	.	PUNCT
fnp-3271	7	1	introduction	introduction	NOUN
fnp-3271	7	2	even	even	ADV
fnp-3271	7	3	though	though	ADV
fnp-3271	7	4	,	,	PUNCT
fnp-3271	7	5	in	in	ADP
fnp-3271	7	6	2020	2020	NUM
fnp-3271	7	7	,	,	PUNCT
fnp-3271	7	8	the	the	DET
fnp-3271	7	9	covid-19	covid-19	PROPN
fnp-3271	7	10	pandemic	pandemic	NOUN
fnp-3271	7	11	had	have	VERB
fnp-3271	7	12	a	a	DET
fnp-3271	7	13	quite	quite	ADV
fnp-3271	7	14	dramatic	dramatic	ADJ
fnp-3271	7	15	,	,	PUNCT
fnp-3271	7	16	worldwide	worldwide	ADJ
fnp-3271	7	17	impact	impact	NOUN
fnp-3271	7	18	on	on	ADP
fnp-3271	7	19	the	the	DET
fnp-3271	7	20	way	way	NOUN
fnp-3271	7	21	we	we	PRON
fnp-3271	7	22	interacted	interact	VERB
fnp-3271	7	23	(	(	PUNCT
fnp-3271	7	24	e.g.	e.g.	ADV
fnp-3271	7	25	wearing	wear	VERB
fnp-3271	7	26	of	of	ADP
fnp-3271	7	27	face	face	NOUN
fnp-3271	7	28	masks	mask	NOUN
fnp-3271	7	29	,	,	PUNCT
fnp-3271	7	30	social	social	ADJ
fnp-3271	7	31	distancing	distancing	NOUN
fnp-3271	7	32	,	,	PUNCT
fnp-3271	7	33	travel	travel	NOUN
fnp-3271	7	34	restrictions	restriction	NOUN
fnp-3271	7	35	,	,	PUNCT
fnp-3271	7	36	or	or	CCONJ
fnp-3271	7	37	even	even	ADV
fnp-3271	7	38	complete	complete	ADJ
fnp-3271	7	39	lockdowns	lockdown	NOUN
fnp-3271	7	40	)	)	PUNCT
fnp-3271	7	41	,	,	PUNCT
fnp-3271	7	42	the	the	DET
fnp-3271	7	43	publication	publication	NOUN
fnp-3271	7	44	of	of	ADP
fnp-3271	7	45	articles	article	NOUN
fnp-3271	7	46	in	in	ADP
fnp-3271	7	47	international	international	ADJ
fnp-3271	7	48	,	,	PUNCT
fnp-3271	7	49	peer	peer	NOUN
fnp-3271	7	50	-	-	PUNCT
fnp-3271	7	51	reviewed	review	VERB
fnp-3271	7	52	scientific	scientific	ADJ
fnp-3271	7	53	journals	journal	NOUN
fnp-3271	7	54	seemed	seem	VERB
fnp-3271	7	55	to	to	PART
fnp-3271	7	56	continue	continue	VERB
fnp-3271	7	57	more	more	ADV
fnp-3271	7	58	or	or	CCONJ
fnp-3271	7	59	less	less	ADJ
fnp-3271	7	60	as	as	ADP
fnp-3271	7	61	usual	usual	ADJ
fnp-3271	7	62	.	.	PUNCT
fnp-3271	8	1	the	the	DET
fnp-3271	8	2	author	author	NOUN
fnp-3271	8	3	of	of	ADP
fnp-3271	8	4	this	this	DET
fnp-3271	8	5	review	review	NOUN
fnp-3271	8	6	was	be	AUX
fnp-3271	8	7	asked	ask	VERB
fnp-3271	8	8	to	to	PART
fnp-3271	8	9	contribute	contribute	VERB
fnp-3271	8	10	a	a	DET
fnp-3271	8	11	review	review	NOUN
fnp-3271	8	12	on	on	ADP
fnp-3271	8	13	the	the	DET
fnp-3271	8	14	‘	'	PUNCT
fnp-3271	8	15	top	top	ADJ
fnp-3271	8	16	10	10	NUM
fnp-3271	8	17	discoveries	discovery	NOUN
fnp-3271	8	18	’	'	PUNCT
fnp-3271	8	19	in	in	ADP
fnp-3271	8	20	neurooncology	neurooncology	NOUN
fnp-3271	8	21	published	publish	VERB
fnp-3271	8	22	in	in	ADP
fnp-3271	8	23	2020	2020	NUM
fnp-3271	8	24	.	.	PUNCT
fnp-3271	9	1	as	as	ADP
fnp-3271	9	2	a	a	DET
fnp-3271	9	3	search	search	NOUN
fnp-3271	9	4	for	for	ADP
fnp-3271	9	5	candidate	candidate	NOUN
fnp-3271	9	6	papers	paper	NOUN
fnp-3271	9	7	in	in	ADP
fnp-3271	9	8	pubmed	pubmed	PROPN
fnp-3271	9	9	using	use	VERB
fnp-3271	9	10	‘	'	PUNCT
fnp-3271	9	11	brain	brain	NOUN
fnp-3271	9	12	&	&	CCONJ
fnp-3271	9	13	tumor	tumor	PROPN
fnp-3271	9	14	&	&	CCONJ
fnp-3271	9	15	2020	2020	NUM
fnp-3271	9	16	’	'	PUNCT
fnp-3271	9	17	or	or	CCONJ
fnp-3271	9	18	‘	'	PUNCT
fnp-3271	9	19	spinal	spinal	ADJ
fnp-3271	9	20	cord	cord	NOUN
fnp-3271	9	21	&	&	CCONJ
fnp-3271	9	22	tumor	tumor	PROPN
fnp-3271	9	23	&	&	CCONJ
fnp-3271	9	24	2020	2020	NUM
fnp-3271	9	25	’	'	PUNCT
fnp-3271	9	26	as	as	SCONJ
fnp-3271	9	27	key	key	ADJ
fnp-3271	9	28	words	word	NOUN
fnp-3271	9	29	resulted	result	VERB
fnp-3271	9	30	in	in	ADP
fnp-3271	9	31	over	over	ADP
fnp-3271	9	32	10,000	10,000	NUM
fnp-3271	9	33	hits	hit	NOUN
fnp-3271	9	34	,	,	PUNCT
fnp-3271	9	35	it	it	PRON
fnp-3271	9	36	took	take	VERB
fnp-3271	9	37	some	some	DET
fnp-3271	9	38	time	time	NOUN
fnp-3271	9	39	before	before	SCONJ
fnp-3271	9	40	the	the	DET
fnp-3271	9	41	selection	selection	NOUN
fnp-3271	9	42	process	process	NOUN
fnp-3271	9	43	for	for	ADP
fnp-3271	9	44	the	the	DET
fnp-3271	9	45	‘	'	PUNCT
fnp-3271	9	46	top	top	ADJ
fnp-3271	9	47	ten	ten	NUM
fnp-3271	9	48	discoveries	discovery	NOUN
fnp-3271	9	49	’	'	PUNCT
fnp-3271	9	50	was	be	AUX
fnp-3271	9	51	finished	finish	VERB
fnp-3271	9	52	.	.	PUNCT
fnp-3271	10	1	here	here	ADV
fnp-3271	10	2	follows	follow	VERB
fnp-3271	10	3	the	the	DET
fnp-3271	10	4	list	list	NOUN
fnp-3271	10	5	of	of	ADP
fnp-3271	10	6	the	the	DET
fnp-3271	10	7	discoveries	discovery	NOUN
fnp-3271	10	8	that	that	PRON
fnp-3271	10	9	emerged	emerge	VERB
fnp-3271	10	10	because	because	SCONJ
fnp-3271	10	11	they	they	PRON
fnp-3271	10	12	can	can	AUX
fnp-3271	10	13	be	be	AUX
fnp-3271	10	14	expected	expect	VERB
fnp-3271	10	15	to	to	PART
fnp-3271	10	16	have	have	VERB
fnp-3271	10	17	substantial	substantial	ADJ
fnp-3271	10	18	implications	implication	NOUN
fnp-3271	10	19	for	for	ADP
fnp-3271	10	20	neurooncological	neurooncological	ADJ
fnp-3271	10	21	pathology	pathology	NOUN
fnp-3271	10	22	:	:	PUNCT
fnp-3271	10	23	infratentorial	infratentorial	ADJ
fnp-3271	10	24	idh	idh	NOUN
fnp-3271	10	25	-	-	PUNCT
fnp-3271	10	26	mutant	mutant	NOUN
fnp-3271	10	27	astrocytomas	astrocytoma	NOUN
fnp-3271	10	28	are	be	AUX
fnp-3271	10	29	different	different	ADJ
fnp-3271	11	1	[	[	X
fnp-3271	11	2	1	1	NUM
fnp-3271	11	3	]	]	X
fnp-3271	11	4	molecular	molecular	ADJ
fnp-3271	11	5	landscape	landscape	NOUN
fnp-3271	11	6	of	of	ADP
fnp-3271	11	7	pediatric	pediatric	ADJ
fnp-3271	11	8	low	low	ADJ
fnp-3271	11	9	-	-	PUNCT
fnp-3271	11	10	grade	grade	NOUN
fnp-3271	11	11	gliomas	glioma	NOUN
fnp-3271	11	12	[	[	X
fnp-3271	11	13	2	2	NUM
fnp-3271	11	14	]	]	PUNCT
fnp-3271	11	15	gene	gene	NOUN
fnp-3271	11	16	fusions	fusion	NOUN
fnp-3271	11	17	in	in	ADP
fnp-3271	11	18	infant	infant	NOUN
fnp-3271	11	19	-	-	PUNCT
fnp-3271	11	20	type	type	NOUN
fnp-3271	11	21	high	high	ADJ
fnp-3271	11	22	-	-	PUNCT
fnp-3271	11	23	grade	grade	NOUN
fnp-3271	11	24	gliomas	glioma	NOUN
fnp-3271	11	25	[	[	X
fnp-3271	11	26	3	3	NUM
fnp-3271	11	27	]	]	X
fnp-3271	11	28	hypermutation	hypermutation	NOUN
fnp-3271	11	29	in	in	ADP
fnp-3271	11	30	gliomas	glioma	NOUN
fnp-3271	11	31	[	[	X
fnp-3271	11	32	4	4	NUM
fnp-3271	11	33	]	]	ADJ
fnp-3271	11	34	immunological	immunological	ADJ
fnp-3271	11	35	aspects	aspect	NOUN
fnp-3271	11	36	of	of	ADP
fnp-3271	11	37	the	the	DET
fnp-3271	11	38	brain	brain	NOUN
fnp-3271	11	39	tumor	tumor	NOUN
fnp-3271	11	40	microenvironment	microenvironment	NOUN
fnp-3271	12	1	[	[	X
fnp-3271	12	2	5	5	NUM
fnp-3271	12	3	-	-	SYM
fnp-3271	12	4	7	7	NUM
fnp-3271	12	5	]	]	X
fnp-3271	12	6	lymphatic	lymphatic	ADJ
fnp-3271	12	7	drainage	drainage	NOUN
fnp-3271	12	8	enables	enable	VERB
fnp-3271	12	9	brain	brain	VERB
fnp-3271	12	10	tumor	tumor	NOUN
fnp-3271	12	11	surveillance	surveillance	NOUN
fnp-3271	13	1	[	[	X
fnp-3271	13	2	8	8	NUM
fnp-3271	13	3	,	,	PUNCT
fnp-3271	13	4	9	9	NUM
fnp-3271	13	5	]	]	SYM
fnp-3271	13	6	impact	impact	NOUN
fnp-3271	13	7	of	of	ADP
fnp-3271	13	8	tumor	tumor	NOUN
fnp-3271	13	9	microenvironment	microenvironment	NOUN
fnp-3271	13	10	on	on	ADP
fnp-3271	13	11	preclinical	preclinical	ADJ
fnp-3271	13	12	glioblastoma	glioblastoma	NOUN
fnp-3271	13	13	models	model	NOUN
fnp-3271	13	14	[	[	X
fnp-3271	13	15	10	10	NUM
fnp-3271	13	16	]	]	PUNCT
fnp-3271	13	17	newly	newly	ADV
fnp-3271	13	18	recognized	recognize	VERB
fnp-3271	13	19	medulloblastoma	medulloblastoma	ADJ
fnp-3271	13	20	predisposition	predisposition	NOUN
fnp-3271	13	21	syndromes	syndrome	NOUN
fnp-3271	13	22	[	[	X
fnp-3271	13	23	11	11	NUM
fnp-3271	13	24	,	,	PUNCT
fnp-3271	13	25	12	12	NUM
fnp-3271	13	26	]	]	PUNCT
fnp-3271	13	27	liquid	liquid	ADJ
fnp-3271	13	28	biopsy	biopsy	NOUN
fnp-3271	13	29	diagnosis	diagnosis	NOUN
fnp-3271	13	30	of	of	ADP
fnp-3271	13	31	cns	cns	NOUN
fnp-3271	13	32	tumors	tumor	NOUN
fnp-3271	13	33	[	[	X
fnp-3271	13	34	13	13	NUM
fnp-3271	13	35	]	]	PUNCT
fnp-3271	13	36	the	the	DET
fnp-3271	13	37	glioblastoma	glioblastoma	NOUN
fnp-3271	13	38	microbiome	microbiome	NOUN
fnp-3271	14	1	[	[	X
fnp-3271	14	2	14	14	NUM
fnp-3271	14	3	]	]	PUNCT
fnp-3271	14	4	the	the	DET
fnp-3271	14	5	order	order	NOUN
fnp-3271	14	6	in	in	ADP
fnp-3271	14	7	this	this	DET
fnp-3271	14	8	list	list	NOUN
fnp-3271	14	9	is	be	AUX
fnp-3271	14	10	not	not	PART
fnp-3271	14	11	based	base	VERB
fnp-3271	14	12	on	on	ADP
fnp-3271	14	13	any	any	DET
fnp-3271	14	14	ranked	rank	VERB
fnp-3271	14	15	importance	importance	NOUN
fnp-3271	14	16	of	of	ADP
fnp-3271	14	17	the	the	DET
fnp-3271	14	18	findings	finding	NOUN
fnp-3271	14	19	but	but	CCONJ
fnp-3271	14	20	reflects	reflect	VERB
fnp-3271	14	21	an	an	DET
fnp-3271	14	22	attempt	attempt	NOUN
fnp-3271	14	23	to	to	PART
fnp-3271	14	24	create	create	VERB
fnp-3271	14	25	some	some	DET
fnp-3271	14	26	flow	flow	NOUN
fnp-3271	14	27	in	in	ADP
fnp-3271	14	28	this	this	DET
fnp-3271	14	29	review	review	NOUN
fnp-3271	14	30	.	.	PUNCT
fnp-3271	15	1	furthermore	furthermore	ADV
fnp-3271	15	2	,	,	PUNCT
fnp-3271	15	3	acknowledging	acknowledge	VERB
fnp-3271	15	4	that	that	SCONJ
fnp-3271	15	5	authors	author	NOUN
fnp-3271	15	6	did	do	VERB
fnp-3271	15	7	their	their	PRON
fnp-3271	15	8	best	good	ADJ
fnp-3271	15	9	to	to	PART
fnp-3271	15	10	optimally	optimally	ADV
fnp-3271	15	11	summarize	summarize	VERB
fnp-3271	15	12	the	the	DET
fnp-3271	15	13	essence	essence	NOUN
fnp-3271	15	14	of	of	ADP
fnp-3271	15	15	their	their	PRON
fnp-3271	15	16	findings	finding	NOUN
fnp-3271	15	17	in	in	ADP
fnp-3271	15	18	(	(	PUNCT
fnp-3271	15	19	especially	especially	ADV
fnp-3271	15	20	the	the	DET
fnp-3271	15	21	abstracts	abstract	NOUN
fnp-3271	15	22	of	of	ADP
fnp-3271	15	23	)	)	PUNCT
fnp-3271	15	24	the	the	DET
fnp-3271	15	25	papers	paper	NOUN
fnp-3271	15	26	,	,	PUNCT
fnp-3271	15	27	in	in	ADP
fnp-3271	15	28	this	this	DET
fnp-3271	15	29	review	review	NOUN
fnp-3271	15	30	several	several	ADJ
fnp-3271	15	31	phrases	phrase	NOUN
fnp-3271	15	32	were	be	AUX
fnp-3271	15	33	copied	copy	VERB
fnp-3271	15	34	and	and	CCONJ
fnp-3271	15	35	pasted	paste	VERB
fnp-3271	15	36	from	from	ADP
fnp-3271	15	37	the	the	DET
fnp-3271	15	38	original	original	ADJ
fnp-3271	15	39	papers	paper	NOUN
fnp-3271	15	40	,	,	PUNCT
fnp-3271	15	41	always	always	ADV
fnp-3271	15	42	accompanied	accompany	VERB
fnp-3271	15	43	by	by	ADP
fnp-3271	15	44	adding	add	VERB
fnp-3271	15	45	the	the	DET
fnp-3271	15	46	reference	reference	NOUN
fnp-3271	15	47	.	.	PUNCT
fnp-3271	16	1	of	of	ADP
fnp-3271	16	2	course	course	NOUN
fnp-3271	16	3	,	,	PUNCT
fnp-3271	16	4	there	there	PRON
fnp-3271	16	5	is	be	VERB
fnp-3271	16	6	quite	quite	DET
fnp-3271	16	7	a	a	DET
fnp-3271	16	8	subjective	subjective	ADJ
fnp-3271	16	9	component	component	NOUN
fnp-3271	16	10	in	in	ADP
fnp-3271	16	11	the	the	DET
fnp-3271	16	12	selection	selection	NOUN
fnp-3271	16	13	of	of	ADP
fnp-3271	16	14	papers	paper	NOUN
fnp-3271	16	15	presented	present	VERB
fnp-3271	16	16	in	in	ADP
fnp-3271	16	17	this	this	DET
fnp-3271	16	18	review	review	NOUN
fnp-3271	16	19	.	.	PUNCT
fnp-3271	17	1	for	for	ADP
fnp-3271	17	2	example	example	NOUN
fnp-3271	17	3	,	,	PUNCT
fnp-3271	17	4	the	the	DET
fnp-3271	17	5	selection	selection	NOUN
fnp-3271	17	6	was	be	AUX
fnp-3271	17	7	not	not	PART
fnp-3271	17	8	per	per	ADP
fnp-3271	17	9	se	se	X
fnp-3271	17	10	solely	solely	ADV
fnp-3271	17	11	based	base	VERB
fnp-3271	17	12	on	on	ADP
fnp-3271	17	13	articles	article	NOUN
fnp-3271	17	14	in	in	ADP
fnp-3271	17	15	the	the	DET
fnp-3271	17	16	high(est)-impact	high(est)-impact	PROPN
fnp-3271	17	17	journals	journal	NOUN
fnp-3271	17	18	but	but	CCONJ
fnp-3271	17	19	also	also	ADV
fnp-3271	17	20	aimed	aim	VERB
fnp-3271	17	21	for	for	ADP
fnp-3271	17	22	a	a	DET
fnp-3271	17	23	somewhat	somewhat	ADV
fnp-3271	17	24	broader	broad	ADJ
fnp-3271	17	25	blend	blend	NOUN
fnp-3271	17	26	of	of	ADP
fnp-3271	17	27	topics	topic	NOUN
fnp-3271	17	28	.	.	PUNCT
fnp-3271	18	1	ergo	ergo	NOUN
fnp-3271	18	2	,	,	PUNCT
fnp-3271	18	3	other	other	ADJ
fnp-3271	18	4	colleagues	colleague	NOUN
fnp-3271	18	5	would	would	AUX
fnp-3271	18	6	probably	probably	ADV
fnp-3271	18	7	have	have	AUX
fnp-3271	18	8	selected	select	VERB
fnp-3271	18	9	other	other	ADJ
fnp-3271	18	10	papers	paper	NOUN
fnp-3271	18	11	,	,	PUNCT
fnp-3271	18	12	but	but	CCONJ
fnp-3271	18	13	,	,	PUNCT
fnp-3271	18	14	as	as	ADV
fnp-3271	18	15	far	far	ADV
fnp-3271	18	16	as	as	SCONJ
fnp-3271	18	17	i	i	PRON
fnp-3271	18	18	am	be	AUX
fnp-3271	18	19	concerned	concern	VERB
fnp-3271	18	20	,	,	PUNCT
fnp-3271	18	21	that	that	PRON
fnp-3271	18	22	is	be	AUX
fnp-3271	18	23	all	all	PRON
fnp-3271	18	24	in	in	ADP
fnp-3271	18	25	the	the	DET
fnp-3271	18	26	game	game	NOUN
fnp-3271	18	27	(	(	PUNCT
fnp-3271	18	28	‘	'	PUNCT
fnp-3271	18	29	de	de	X
fnp-3271	18	30	gustibus	gustibus	X
fnp-3271	18	31	non	non	X
fnp-3271	18	32	est	est	X
fnp-3271	18	33	disputandum	disputandum	NOUN
fnp-3271	18	34	’	'	PUNCT
fnp-3271	18	35	)	)	PUNCT
fnp-3271	18	36	.	.	PUNCT
fnp-3271	19	1	to	to	PART
fnp-3271	19	2	make	make	VERB
fnp-3271	19	3	up	up	ADP
fnp-3271	19	4	for	for	ADP
fnp-3271	19	5	this	this	DET
fnp-3271	19	6	situation	situation	NOUN
fnp-3271	19	7	to	to	ADP
fnp-3271	19	8	some	some	DET
fnp-3271	19	9	degree	degree	NOUN
fnp-3271	19	10	,	,	PUNCT
fnp-3271	19	11	a	a	DET
fnp-3271	19	12	few	few	ADJ
fnp-3271	19	13	papers	paper	NOUN
fnp-3271	19	14	that	that	PRON
fnp-3271	19	15	just	just	ADV
fnp-3271	19	16	did	do	AUX
fnp-3271	19	17	not	not	PART
fnp-3271	19	18	make	make	VERB
fnp-3271	19	19	it	it	PRON
fnp-3271	19	20	to	to	ADP
fnp-3271	19	21	my	my	PRON
fnp-3271	19	22	top	top	ADJ
fnp-3271	19	23	10	10	NUM
fnp-3271	19	24	list	list	NOUN
fnp-3271	19	25	will	will	AUX
fnp-3271	19	26	be	be	AUX
fnp-3271	19	27	briefly	briefly	ADV
fnp-3271	19	28	mentioned	mention	VERB
fnp-3271	19	29	in	in	ADP
fnp-3271	19	30	the	the	DET
fnp-3271	19	31	discussion	discussion	NOUN
fnp-3271	19	32	.	.	PUNCT
fnp-3271	20	1	because	because	SCONJ
fnp-3271	20	2	of	of	ADP
fnp-3271	20	3	the	the	DET
fnp-3271	20	4	extraordinary	extraordinary	ADJ
fnp-3271	20	5	impact	impact	NOUN
fnp-3271	20	6	of	of	ADP
fnp-3271	20	7	the	the	DET
fnp-3271	20	8	covid-19	covid-19	PROPN
fnp-3271	20	9	pandemic	pandemic	NOUN
fnp-3271	20	10	in	in	ADP
fnp-3271	20	11	2020	2020	NUM
fnp-3271	20	12	on	on	ADP
fnp-3271	20	13	our	our	PRON
fnp-3271	20	14	(	(	PUNCT
fnp-3271	20	15	professional	professional	ADJ
fnp-3271	20	16	)	)	PUNCT
fnp-3271	20	17	lives	life	NOUN
fnp-3271	20	18	,	,	PUNCT
fnp-3271	20	19	some	some	DET
fnp-3271	20	20	covid-19	covid-19	PROPN
fnp-3271	20	21	aspects	aspect	NOUN
fnp-3271	20	22	related	relate	VERB
fnp-3271	20	23	to	to	ADP
fnp-3271	20	24	neurooncological	neurooncological	ADJ
fnp-3271	20	25	pathology	pathology	NOUN
fnp-3271	20	26	are	be	AUX
fnp-3271	20	27	very	very	ADV
fnp-3271	20	28	briefly	briefly	ADV
fnp-3271	20	29	discussed	discuss	VERB
fnp-3271	20	30	as	as	ADV
fnp-3271	20	31	well	well	ADV
fnp-3271	20	32	.	.	PUNCT
fnp-3271	21	1	topic	topic	NOUN
fnp-3271	21	2	1	1	NUM
fnp-3271	21	3	.	.	PUNCT
fnp-3271	21	4	infratentorial	infratentorial	ADJ
fnp-3271	21	5	idh	idh	NOUN
fnp-3271	21	6	-	-	PUNCT
fnp-3271	21	7	mutant	mutant	NOUN
fnp-3271	21	8	astrocytomas	astrocytoma	NOUN
fnp-3271	21	9	are	be	AUX
fnp-3271	21	10	different	different	ADJ
fnp-3271	21	11	[	[	X
fnp-3271	21	12	1	1	NUM
fnp-3271	21	13	]	]	PUNCT
fnp-3271	21	14	in	in	ADP
fnp-3271	21	15	the	the	DET
fnp-3271	21	16	world	world	PROPN
fnp-3271	21	17	health	health	NOUN
fnp-3271	21	18	organization	organization	NOUN
fnp-3271	21	19	(	(	PUNCT
fnp-3271	21	20	who	who	PRON
fnp-3271	21	21	)	)	PUNCT
fnp-3271	21	22	2016	2016	NUM
fnp-3271	21	23	classification	classification	NOUN
fnp-3271	21	24	,	,	PUNCT
fnp-3271	21	25	three	three	NUM
fnp-3271	21	26	main	main	ADJ
fnp-3271	21	27	groups	group	NOUN
fnp-3271	21	28	of	of	ADP
fnp-3271	21	29	adult	adult	NOUN
fnp-3271	21	30	-	-	PUNCT
fnp-3271	21	31	type	type	NOUN
fnp-3271	21	32	diffuse	diffuse	NOUN
fnp-3271	21	33	gliomas	glioma	NOUN
fnp-3271	21	34	are	be	AUX
fnp-3271	21	35	listed	list	VERB
fnp-3271	21	36	:	:	PUNCT
fnp-3271	21	37	astrocytomas	astrocytoma	NOUN
fnp-3271	21	38	,	,	PUNCT
fnp-3271	21	39	idh	idh	NOUN
fnp-3271	21	40	-	-	PUNCT
fnp-3271	21	41	mutant	mutant	NOUN
fnp-3271	21	42	;	;	PUNCT
fnp-3271	21	43	oligodendrogliomas	oligodendroglioma	NOUN
fnp-3271	21	44	,	,	PUNCT
fnp-3271	21	45	idh	idh	NOUN
fnp-3271	21	46	-	-	PUNCT
fnp-3271	21	47	mutant	mutant	NOUN
fnp-3271	21	48	and	and	CCONJ
fnp-3271	21	49	1p/19q	1p/19q	NOUN
fnp-3271	21	50	-	-	PUNCT
fnp-3271	21	51	codeleted	codelete	VERB
fnp-3271	21	52	;	;	PUNCT
fnp-3271	21	53	and	and	CCONJ
fnp-3271	21	54	astrocytomas	astrocytoma	NOUN
fnp-3271	21	55	,	,	PUNCT
fnp-3271	21	56	idh	idh	NOUN
fnp-3271	21	57	-	-	PUNCT
fnp-3271	21	58	wildtype	wildtype	NOUN
fnp-3271	21	59	(	(	PUNCT
fnp-3271	21	60	with	with	ADP
fnp-3271	21	61	glioblastoma	glioblastoma	NOUN
fnp-3271	21	62	idh	idh	NOUN
fnp-3271	21	63	-	-	PUNCT
fnp-3271	21	64	wildtype	wildtype	NOUN
fnp-3271	21	65	as	as	ADP
fnp-3271	21	66	by	by	ADP
fnp-3271	21	67	far	far	ADV
fnp-3271	21	68	the	the	DET
fnp-3271	21	69	most	most	ADV
fnp-3271	21	70	frequent	frequent	ADJ
fnp-3271	21	71	representative	representative	NOUN
fnp-3271	21	72	in	in	ADP
fnp-3271	21	73	this	this	DET
fnp-3271	21	74	last	last	ADJ
fnp-3271	21	75	group	group	NOUN
fnp-3271	21	76	)	)	PUNCT
fnp-3271	22	1	[	[	X
fnp-3271	22	2	15	15	NUM
fnp-3271	22	3	]	]	PUNCT
fnp-3271	22	4	.	.	PUNCT
fnp-3271	23	1	in	in	ADP
fnp-3271	23	2	the	the	DET
fnp-3271	23	3	upcoming	upcoming	ADJ
fnp-3271	23	4	5th	5th	ADJ
fnp-3271	23	5	edition	edition	NOUN
fnp-3271	23	6	of	of	ADP
fnp-3271	23	7	the	the	PRON
fnp-3271	23	8	who	who	PRON
fnp-3271	23	9	classification	classification	VERB
fnp-3271	23	10	(	(	PUNCT
fnp-3271	23	11	to	to	PART
fnp-3271	23	12	be	be	AUX
fnp-3271	23	13	published	publish	VERB
fnp-3271	23	14	in	in	ADP
fnp-3271	23	15	2021	2021	NUM
fnp-3271	23	16	)	)	PUNCT
fnp-3271	23	17	,	,	PUNCT
fnp-3271	23	18	some	some	DET
fnp-3271	23	19	changes	change	NOUN
fnp-3271	23	20	can	can	AUX
fnp-3271	23	21	be	be	AUX
fnp-3271	23	22	expected	expect	VERB
fnp-3271	23	23	in	in	ADP
fnp-3271	23	24	the	the	DET
fnp-3271	23	25	definitions	definition	NOUN
fnp-3271	23	26	and	and	CCONJ
fnp-3271	23	27	nomenclature	nomenclature	NOUN
fnp-3271	23	28	of	of	ADP
fnp-3271	23	29	idh	idh	NOUN
fnp-3271	23	30	-	-	PUNCT
fnp-3271	23	31	mutant	mutant	NOUN
fnp-3271	23	32	astrocytomas	astrocytoma	NOUN
fnp-3271	23	33	.	.	PUNCT
fnp-3271	24	1	this	this	PRON
fnp-3271	24	2	is	be	AUX
fnp-3271	24	3	in	in	ADP
fnp-3271	24	4	line	line	NOUN
fnp-3271	24	5	with	with	ADP
fnp-3271	24	6	what	what	PRON
fnp-3271	24	7	has	have	AUX
fnp-3271	24	8	been	be	AUX
fnp-3271	24	9	proposed	propose	VERB
fnp-3271	24	10	by	by	ADP
fnp-3271	24	11	different	different	ADJ
fnp-3271	24	12	updates	update	NOUN
fnp-3271	24	13	of	of	ADP
fnp-3271	24	14	the	the	DET
fnp-3271	24	15	consortium	consortium	NOUN
fnp-3271	24	16	to	to	PART
fnp-3271	24	17	improve	improve	VERB
fnp-3271	24	18	molecular	molecular	ADJ
fnp-3271	24	19	and	and	CCONJ
fnp-3271	24	20	practical	practical	ADJ
fnp-3271	24	21	approaches	approach	NOUN
fnp-3271	24	22	to	to	ADP
fnp-3271	24	23	cns	cns	PROPN
fnp-3271	24	24	tumor	tumor	NOUN
fnp-3271	24	25	taxonomy	taxonomy	NOUN
fnp-3271	24	26	(	(	PUNCT
fnp-3271	24	27	cimpact	cimpact	VERB
fnp-3271	24	28	-	-	PUNCT
fnp-3271	24	29	now	now	ADV
fnp-3271	24	30	)	)	PUNCT
fnp-3271	24	31	.	.	PUNCT
fnp-3271	25	1	cimpact	cimpact	ADJ
fnp-3271	25	2	-	-	PUNCT
fnp-3271	25	3	now	now	ADV
fnp-3271	25	4	update	update	NOUN
fnp-3271	25	5	5	5	NUM
fnp-3271	25	6	suggested	suggest	VERB
fnp-3271	25	7	to	to	PART
fnp-3271	25	8	grade	grade	VERB
fnp-3271	25	9	the	the	DET
fnp-3271	25	10	idh	idh	NOUN
fnp-3271	25	11	-	-	PUNCT
fnp-3271	25	12	mutant	mutant	NOUN
fnp-3271	25	13	astrocytomas	astrocytoma	NOUN
fnp-3271	25	14	as	as	ADP
fnp-3271	25	15	who	who	PRON
fnp-3271	25	16	grade	grade	VERB
fnp-3271	25	17	iv	iv	ADP
fnp-3271	25	18	if	if	SCONJ
fnp-3271	25	19	molecular	molecular	ADJ
fnp-3271	25	20	analysis	analysis	NOUN
fnp-3271	25	21	reveals	reveal	VERB
fnp-3271	25	22	the	the	DET
fnp-3271	25	23	presence	presence	NOUN
fnp-3271	25	24	of	of	ADP
fnp-3271	25	25	homozygous	homozygous	ADJ
fnp-3271	25	26	cdkn2a	cdkn2a	PROPN
fnp-3271	25	27	/	/	SYM
fnp-3271	25	28	b	b	NOUN
fnp-3271	25	29	deletion	deletion	NOUN
fnp-3271	25	30	and	and	CCONJ
fnp-3271	25	31	not	not	PART
fnp-3271	25	32	only	only	ADV
fnp-3271	25	33	if	if	SCONJ
fnp-3271	25	34	the	the	DET
fnp-3271	25	35	tumor	tumor	NOUN
fnp-3271	25	36	histologically	histologically	ADV
fnp-3271	25	37	shows	show	VERB
fnp-3271	25	38	features	feature	NOUN
fnp-3271	25	39	of	of	ADP
fnp-3271	25	40	the	the	DET
fnp-3271	25	41	highest	high	ADJ
fnp-3271	25	42	malignancy	malignancy	NOUN
fnp-3271	25	43	grade	grade	NOUN
fnp-3271	25	44	[	[	X
fnp-3271	25	45	16	16	NUM
fnp-3271	25	46	]	]	PUNCT
fnp-3271	25	47	.	.	PUNCT
fnp-3271	26	1	furthermore	furthermore	ADV
fnp-3271	26	2	,	,	PUNCT
fnp-3271	26	3	cimpact	cimpact	ADJ
fnp-3271	26	4	-	-	PUNCT
fnp-3271	26	5	now	now	ADV
fnp-3271	26	6	update	update	NOUN
fnp-3271	26	7	6	6	NUM
fnp-3271	26	8	proposed	propose	VERB
fnp-3271	26	9	to	to	PART
fnp-3271	26	10	group	group	VERB
fnp-3271	26	11	the	the	DET
fnp-3271	26	12	who	who	PRON
fnp-3271	26	13	grade	grade	NOUN
fnp-3271	26	14	ii	ii	NOUN
fnp-3271	26	15	-	-	PUNCT
fnp-3271	26	16	iv	iv	NUM
fnp-3271	26	17	diffuse	diffuse	NOUN
fnp-3271	26	18	idh	idh	NOUN
fnp-3271	26	19	-	-	PUNCT
fnp-3271	26	20	mutant	mutant	NOUN
fnp-3271	26	21	astrocytic	astrocytic	ADJ
fnp-3271	26	22	tumors	tumor	NOUN
fnp-3271	26	23	under	under	ADP
fnp-3271	26	24	a	a	DET
fnp-3271	26	25	single	single	ADJ
fnp-3271	26	26	name	name	NOUN
fnp-3271	26	27	(	(	PUNCT
fnp-3271	26	28	“	"	PUNCT
fnp-3271	26	29	astrocytoma	astrocytoma	NOUN
fnp-3271	26	30	,	,	PUNCT
fnp-3271	26	31	idh	idh	NOUN
fnp-3271	26	32	mutant	mutant	NOUN
fnp-3271	26	33	”	"	PUNCT
fnp-3271	26	34	)	)	PUNCT
fnp-3271	26	35	with	with	ADP
fnp-3271	26	36	arabic	arabic	ADJ
fnp-3271	26	37	numerals	numeral	NOUN
fnp-3271	26	38	assigned	assign	VERB
fnp-3271	26	39	for	for	ADP
fnp-3271	26	40	the	the	DET
fnp-3271	26	41	grade	grade	NOUN
fnp-3271	26	42	.	.	PUNCT
fnp-3271	27	1	the	the	DET
fnp-3271	27	2	most	most	ADV
fnp-3271	27	3	malignant	malignant	ADJ
fnp-3271	27	4	form	form	NOUN
fnp-3271	27	5	in	in	ADP
fnp-3271	27	6	this	this	DET
fnp-3271	27	7	group	group	NOUN
fnp-3271	27	8	would	would	AUX
fnp-3271	27	9	then	then	ADV
fnp-3271	27	10	be	be	AUX
fnp-3271	27	11	‘	'	PUNCT
fnp-3271	27	12	astrocytoma	astrocytoma	X
fnp-3271	27	13	,	,	PUNCT
fnp-3271	27	14	idh	idh	NOUN
fnp-3271	27	15	-	-	PUNCT
fnp-3271	27	16	mutant	mutant	NOUN
fnp-3271	27	17	,	,	PUNCT
fnp-3271	27	18	grade	grade	NOUN
fnp-3271	27	19	4	4	NUM
fnp-3271	27	20	’	'	PUNCT
fnp-3271	27	21	(	(	PUNCT
fnp-3271	27	22	rather	rather	ADV
fnp-3271	27	23	than	than	ADP
fnp-3271	27	24	‘	'	PUNCT
fnp-3271	27	25	glioblastoma	glioblastoma	NOUN
fnp-3271	27	26	,	,	PUNCT
fnp-3271	27	27	idh	idh	NOUN
fnp-3271	27	28	-	-	PUNCT
fnp-3271	27	29	mutant	mutant	NOUN
fnp-3271	27	30	’	'	PUNCT
fnp-3271	27	31	)	)	PUNCT
fnp-3271	27	32	,	,	PUNCT
fnp-3271	27	33	facilitating	facilitate	VERB
fnp-3271	27	34	discrimination	discrimination	NOUN
fnp-3271	27	35	from	from	ADP
fnp-3271	27	36	the	the	DET
fnp-3271	27	37	much	much	ADV
fnp-3271	27	38	more	more	ADV
fnp-3271	27	39	frequent	frequent	ADJ
fnp-3271	27	40	and	and	CCONJ
fnp-3271	27	41	more	more	ADV
fnp-3271	27	42	aggressive	aggressive	ADJ
fnp-3271	27	43	‘	'	PUNCT
fnp-3271	27	44	idh	idh	ADJ
fnp-3271	27	45	–	–	PUNCT
fnp-3271	27	46	wildtype	wildtype	NOUN
fnp-3271	27	47	glioblastoma	glioblastoma	NOUN
fnp-3271	27	48	’	'	PUNCT
fnp-3271	27	49	[	[	X
fnp-3271	27	50	17	17	NUM
fnp-3271	27	51	]	]	PUNCT
fnp-3271	27	52	.	.	PUNCT
fnp-3271	28	1	in	in	ADP
fnp-3271	28	2	these	these	DET
fnp-3271	28	3	considerations	consideration	NOUN
fnp-3271	28	4	,	,	PUNCT
fnp-3271	28	5	the	the	DET
fnp-3271	28	6	location	location	NOUN
fnp-3271	28	7	of	of	ADP
fnp-3271	28	8	the	the	DET
fnp-3271	28	9	idh	idh	NOUN
fnp-3271	28	10	-	-	PUNCT
fnp-3271	28	11	mutant	mutant	NOUN
fnp-3271	28	12	astrocytic	astrocytic	ADJ
fnp-3271	28	13	tumors	tumor	NOUN
fnp-3271	28	14	is	be	AUX
fnp-3271	28	15	not	not	PART
fnp-3271	28	16	taken	take	VERB
fnp-3271	28	17	into	into	ADP
fnp-3271	28	18	account	account	NOUN
fnp-3271	28	19	.	.	PUNCT
fnp-3271	29	1	indeed	indeed	ADV
fnp-3271	29	2	,	,	PUNCT
fnp-3271	29	3	in	in	ADP
fnp-3271	29	4	the	the	DET
fnp-3271	29	5	vast	vast	ADJ
fnp-3271	29	6	majority	majority	NOUN
fnp-3271	29	7	of	of	ADP
fnp-3271	29	8	patients	patient	NOUN
fnp-3271	29	9	presenting	present	VERB
fnp-3271	29	10	with	with	ADP
fnp-3271	29	11	a	a	DET
fnp-3271	29	12	diffuse	diffuse	ADJ
fnp-3271	29	13	idh	idh	NOUN
fnp-3271	29	14	-	-	PUNCT
fnp-3271	29	15	mutant	mutant	NOUN
fnp-3271	29	16	astrocytoma	astrocytoma	NOUN
fnp-3271	29	17	,	,	PUNCT
fnp-3271	29	18	the	the	DET
fnp-3271	29	19	tumor	tumor	NOUN
fnp-3271	29	20	is	be	AUX
fnp-3271	29	21	located	locate	VERB
fnp-3271	29	22	in	in	ADP
fnp-3271	29	23	a	a	DET
fnp-3271	29	24	cerebral	cerebral	ADJ
fnp-3271	29	25	hemisphere	hemisphere	NOUN
fnp-3271	29	26	.	.	PUNCT
fnp-3271	30	1	banan	banan	PROPN
fnp-3271	30	2	r	r	PROPN
fnp-3271	30	3	et	et	NOUN
fnp-3271	30	4	al	al	PROPN
fnp-3271	30	5	(	(	PUNCT
fnp-3271	30	6	with	with	ADP
fnp-3271	30	7	hartmann	hartmann	PROPN
fnp-3271	30	8	c	c	PROPN
fnp-3271	30	9	and	and	CCONJ
fnp-3271	30	10	reuss	reuss	PROPN
fnp-3271	30	11	d	d	PROPN
fnp-3271	30	12	as	as	ADP
fnp-3271	30	13	corresponding	corresponding	ADJ
fnp-3271	30	14	authors	author	NOUN
fnp-3271	30	15	)	)	PUNCT
fnp-3271	30	16	published	publish	VERB
fnp-3271	30	17	in	in	ADP
fnp-3271	30	18	acta	acta	PROPN
fnp-3271	30	19	neuropathologica	neuropathologica	PROPN
fnp-3271	30	20	the	the	DET
fnp-3271	30	21	clinical	clinical	ADJ
fnp-3271	30	22	and	and	CCONJ
fnp-3271	30	23	pathological	pathological	ADJ
fnp-3271	30	24	characteristics	characteristic	NOUN
fnp-3271	30	25	of	of	ADP
fnp-3271	30	26	a	a	DET
fnp-3271	30	27	series	series	NOUN
fnp-3271	30	28	of	of	ADP
fnp-3271	30	29	42	42	NUM
fnp-3271	30	30	primary	primary	ADJ
fnp-3271	30	31	infratentorial	infratentorial	ADJ
fnp-3271	30	32	idh	idh	NOUN
fnp-3271	30	33	-	-	PUNCT
fnp-3271	30	34	mutant	mutant	NOUN
fnp-3271	30	35	astrocytic	astrocytic	ADJ
fnp-3271	30	36	tumors	tumor	NOUN
fnp-3271	31	1	[	[	X
fnp-3271	31	2	1	1	NUM
fnp-3271	31	3	]	]	PUNCT
fnp-3271	31	4	.	.	PUNCT
fnp-3271	32	1	the	the	DET
fnp-3271	32	2	mean	mean	ADJ
fnp-3271	32	3	age	age	NOUN
fnp-3271	32	4	of	of	ADP
fnp-3271	32	5	the	the	DET
fnp-3271	32	6	patients	patient	NOUN
fnp-3271	32	7	in	in	ADP
fnp-3271	32	8	this	this	DET
fnp-3271	32	9	series	series	NOUN
fnp-3271	32	10	was	be	AUX
fnp-3271	32	11	37	37	NUM
fnp-3271	32	12	years	year	NOUN
fnp-3271	32	13	(	(	PUNCT
fnp-3271	32	14	similar	similar	ADJ
fnp-3271	32	15	to	to	ADP
fnp-3271	32	16	the	the	DET
fnp-3271	32	17	patients	patient	NOUN
fnp-3271	32	18	with	with	ADP
fnp-3271	32	19	supratentorial	supratentorial	ADJ
fnp-3271	32	20	tumors	tumor	NOUN
fnp-3271	32	21	)	)	PUNCT
fnp-3271	32	22	,	,	PUNCT
fnp-3271	32	23	the	the	DET
fnp-3271	32	24	male	male	NOUN
fnp-3271	32	25	:	:	PUNCT
fnp-3271	32	26	female	female	ADJ
fnp-3271	32	27	ratio	ratio	NOUN
fnp-3271	32	28	was	be	AUX
fnp-3271	32	29	1.8:1	1.8:1	NUM
fnp-3271	32	30	,	,	PUNCT
fnp-3271	32	31	and	and	CCONJ
fnp-3271	32	32	approximately	approximately	ADV
fnp-3271	32	33	30	30	NUM
fnp-3271	32	34	%	%	NOUN
fnp-3271	32	35	,	,	PUNCT
fnp-3271	32	36	40	40	NUM
fnp-3271	32	37	%	%	NOUN
fnp-3271	32	38	and	and	CCONJ
fnp-3271	32	39	30	30	NUM
fnp-3271	32	40	%	%	NOUN
fnp-3271	32	41	were	be	AUX
fnp-3271	32	42	considered	consider	VERB
fnp-3271	32	43	to	to	PART
fnp-3271	32	44	be	be	AUX
fnp-3271	32	45	who	who	PRON
fnp-3271	32	46	grade	grade	PROPN
fnp-3271	32	47	ii	ii	PROPN
fnp-3271	32	48	,	,	PUNCT
fnp-3271	32	49	iii	iii	PROPN
fnp-3271	32	50	and	and	CCONJ
fnp-3271	32	51	iv	iv	NUM
fnp-3271	32	52	,	,	PUNCT
fnp-3271	32	53	respectively	respectively	ADV
fnp-3271	32	54	.	.	PUNCT
fnp-3271	33	1	interestingly	interestingly	ADV
fnp-3271	33	2	,	,	PUNCT
fnp-3271	33	3	only	only	ADV
fnp-3271	33	4	1	1	NUM
fnp-3271	33	5	out	out	ADP
fnp-3271	33	6	of	of	ADP
fnp-3271	33	7	4	4	NUM
fnp-3271	33	8	of	of	ADP
fnp-3271	33	9	these	these	DET
fnp-3271	33	10	infratentorial	infratentorial	ADJ
fnp-3271	33	11	idh	idh	NOUN
fnp-3271	33	12	-	-	PUNCT
fnp-3271	33	13	mutant	mutant	NOUN
fnp-3271	33	14	tumors	tumor	NOUN
fnp-3271	33	15	had	have	VERB
fnp-3271	33	16	the	the	DET
fnp-3271	33	17	idh1	idh1	NOUN
fnp-3271	33	18	r132h	r132h	PROPN
fnp-3271	33	19	mutation	mutation	NOUN
fnp-3271	33	20	(	(	PUNCT
fnp-3271	33	21	in	in	ADP
fnp-3271	33	22	supratentorial	supratentorial	ADJ
fnp-3271	33	23	tumors	tumor	NOUN
fnp-3271	33	24	this	this	PRON
fnp-3271	33	25	is	be	AUX
fnp-3271	33	26	>	>	X
fnp-3271	33	27	80	80	NUM
fnp-3271	33	28	%	%	NOUN
fnp-3271	33	29	)	)	PUNCT
fnp-3271	33	30	,	,	PUNCT
fnp-3271	33	31	with	with	ADP
fnp-3271	33	32	idh1	idh1	PROPN
fnp-3271	33	33	r132c	r132c	PROPN
fnp-3271	33	34	/	/	SYM
fnp-3271	33	35	g	g	PROPN
fnp-3271	33	36	and	and	CCONJ
fnp-3271	33	37	idh2	idh2	PROPN
fnp-3271	33	38	r172s	r172s	PROPN
fnp-3271	33	39	/	/	SYM
fnp-3271	33	40	g	g	PROPN
fnp-3271	33	41	as	as	ADP
fnp-3271	33	42	the	the	DET
fnp-3271	33	43	most	most	ADV
fnp-3271	33	44	frequent	frequent	ADJ
fnp-3271	33	45	‘	'	PUNCT
fnp-3271	33	46	other	other	ADJ
fnp-3271	33	47	’	'	PUNCT
fnp-3271	33	48	idh	idh	NOUN
fnp-3271	33	49	mutations	mutation	NOUN
fnp-3271	33	50	.	.	PUNCT
fnp-3271	34	1	also	also	ADV
fnp-3271	34	2	,	,	PUNCT
fnp-3271	34	3	atrx	atrx	NOUN
fnp-3271	34	4	loss	loss	NOUN
fnp-3271	34	5	and	and	CCONJ
fnp-3271	34	6	mgmt	mgmt	NOUN
fnp-3271	34	7	promoter	promoter	NOUN
fnp-3271	34	8	methylation	methylation	NOUN
fnp-3271	34	9	were	be	AUX
fnp-3271	34	10	significantly	significantly	ADV
fnp-3271	34	11	less	less	ADV
fnp-3271	34	12	frequently	frequently	ADV
fnp-3271	34	13	found	find	VERB
fnp-3271	34	14	in	in	ADP
fnp-3271	34	15	the	the	DET
fnp-3271	34	16	infratentorial	infratentorial	ADJ
fnp-3271	34	17	compartment	compartment	NOUN
fnp-3271	34	18	.	.	PUNCT
fnp-3271	35	1	of	of	ADP
fnp-3271	35	2	note	note	NOUN
fnp-3271	35	3	,	,	PUNCT
fnp-3271	35	4	gene	gene	NOUN
fnp-3271	35	5	panel	panel	NOUN
fnp-3271	35	6	sequencing	sequencing	NOUN
fnp-3271	35	7	revealed	reveal	VERB
fnp-3271	35	8	two	two	NUM
fnp-3271	35	9	samples	sample	NOUN
fnp-3271	35	10	with	with	ADP
fnp-3271	35	11	idh1	idh1	PROPN
fnp-3271	35	12	r132c	r132c	PROPN
fnp-3271	35	13	/	/	SYM
fnp-3271	35	14	h3f3a	h3f3a	PUNCT
fnp-3271	35	15	k27	k27	PROPN
fnp-3271	35	16	m	m	PROPN
fnp-3271	35	17	co	co	NOUN
fnp-3271	35	18	-	-	NOUN
fnp-3271	35	19	mutations	mutation	NOUN
fnp-3271	35	20	in	in	ADP
fnp-3271	35	21	this	this	DET
fnp-3271	35	22	series	series	NOUN
fnp-3271	35	23	.	.	PUNCT
fnp-3271	36	1	overall	overall	ADV
fnp-3271	36	2	,	,	PUNCT
fnp-3271	36	3	the	the	DET
fnp-3271	36	4	clinical	clinical	ADJ
fnp-3271	36	5	outcomes	outcome	NOUN
fnp-3271	36	6	of	of	ADP
fnp-3271	36	7	patients	patient	NOUN
fnp-3271	36	8	with	with	ADP
fnp-3271	36	9	infratentorial	infratentorial	ADJ
fnp-3271	36	10	idh	idh	NOUN
fnp-3271	36	11	-	-	PUNCT
fnp-3271	36	12	mutant	mutant	NOUN
fnp-3271	36	13	astrocytomas	astrocytoma	NOUN
fnp-3271	36	14	were	be	AUX
fnp-3271	36	15	significantly	significantly	ADV
fnp-3271	36	16	better	well	ADJ
fnp-3271	36	17	than	than	ADP
fnp-3271	36	18	for	for	ADP
fnp-3271	36	19	patients	patient	NOUN
fnp-3271	36	20	with	with	ADP
fnp-3271	36	21	diffuse	diffuse	ADJ
fnp-3271	36	22	midline	midline	NOUN
fnp-3271	36	23	gliomas	glioma	NOUN
fnp-3271	36	24	,	,	PUNCT
fnp-3271	36	25	h3k27m	h3k27m	NOUN
fnp-3271	36	26	-	-	ADJ
fnp-3271	36	27	mutant	mutant	NOUN
fnp-3271	36	28	but	but	CCONJ
fnp-3271	36	29	were	be	AUX
fnp-3271	36	30	significantly	significantly	ADV
fnp-3271	36	31	worse	bad	ADJ
fnp-3271	36	32	than	than	ADP
fnp-3271	36	33	for	for	ADP
fnp-3271	36	34	patients	patient	NOUN
fnp-3271	36	35	with	with	ADP
fnp-3271	36	36	supratentorial	supratentorial	ADJ
fnp-3271	36	37	idh	idh	NOUN
fnp-3271	36	38	-	-	PUNCT
fnp-3271	36	39	mutant	mutant	NOUN
fnp-3271	36	40	astrocytomas	astrocytoma	NOUN
fnp-3271	36	41	when	when	SCONJ
fnp-3271	36	42	the	the	DET
fnp-3271	36	43	two	two	NUM
fnp-3271	36	44	cases	case	NOUN
fnp-3271	36	45	with	with	ADP
fnp-3271	36	46	idh1	idh1	PROPN
fnp-3271	36	47	/	/	SYM
fnp-3271	36	48	h3k27	h3k27	PROPN
fnp-3271	36	49	m	m	PROPN
fnp-3271	36	50	co	co	NOUN
fnp-3271	36	51	-	-	NOUN
fnp-3271	36	52	mutation	mutation	NOUN
fnp-3271	36	53	were	be	AUX
fnp-3271	36	54	included	include	VERB
fnp-3271	36	55	.	.	PUNCT
fnp-3271	37	1	after	after	ADP
fnp-3271	37	2	exclusion	exclusion	NOUN
fnp-3271	37	3	of	of	ADP
fnp-3271	37	4	these	these	DET
fnp-3271	37	5	two	two	NUM
fnp-3271	37	6	cases	case	NOUN
fnp-3271	37	7	,	,	PUNCT
fnp-3271	37	8	only	only	ADV
fnp-3271	37	9	a	a	DET
fnp-3271	37	10	trend	trend	NOUN
fnp-3271	37	11	toward	toward	ADP
fnp-3271	37	12	worse	bad	ADJ
fnp-3271	37	13	outcome	outcome	NOUN
fnp-3271	37	14	for	for	ADP
fnp-3271	37	15	infratentorial	infratentorial	ADJ
fnp-3271	37	16	idh	idh	NOUN
fnp-3271	37	17	-	-	PUNCT
fnp-3271	37	18	mutant	mutant	NOUN
fnp-3271	37	19	astrocytomas	astrocytoma	NOUN
fnp-3271	37	20	was	be	AUX
fnp-3271	37	21	seen	see	VERB
fnp-3271	37	22	.	.	PUNCT
fnp-3271	38	1	this	this	DET
fnp-3271	38	2	study	study	NOUN
fnp-3271	38	3	shows	show	VERB
fnp-3271	38	4	that	that	SCONJ
fnp-3271	38	5	diffuse	diffuse	VERB
fnp-3271	38	6	gliomas	glioma	NOUN
fnp-3271	38	7	in	in	ADP
fnp-3271	38	8	the	the	DET
fnp-3271	38	9	brainstem	brainstem	NOUN
fnp-3271	38	10	and	and	CCONJ
fnp-3271	38	11	cerebellum	cerebellum	NOUN
fnp-3271	38	12	are	be	AUX
fnp-3271	38	13	easily	easily	ADV
fnp-3271	38	14	missed	miss	VERB
fnp-3271	38	15	as	as	ADP
fnp-3271	38	16	being	be	AUX
fnp-3271	38	17	idh	idh	NOUN
fnp-3271	38	18	-	-	PUNCT
fnp-3271	38	19	mutant	mutant	NOUN
fnp-3271	38	20	in	in	ADP
fnp-3271	38	21	cases	case	NOUN
fnp-3271	38	22	where	where	SCONJ
fnp-3271	38	23	only	only	ADJ
fnp-3271	38	24	immunohistochemistry	immunohistochemistry	NOUN
fnp-3271	38	25	for	for	ADP
fnp-3271	38	26	idh1	idh1	PROPN
fnp-3271	38	27	r132h	r132h	PROPN
fnp-3271	38	28	mutant	mutant	ADJ
fnp-3271	38	29	protein	protein	NOUN
fnp-3271	38	30	is	be	AUX
fnp-3271	38	31	performed	perform	VERB
fnp-3271	38	32	and	and	CCONJ
fnp-3271	38	33	that	that	SCONJ
fnp-3271	38	34	h3k27	h3k27	PROPN
fnp-3271	38	35	m	m	PROPN
fnp-3271	38	36	mutations	mutation	NOUN
fnp-3271	38	37	co	co	VERB
fnp-3271	38	38	-	-	VERB
fnp-3271	38	39	occur	occur	VERB
fnp-3271	38	40	in	in	ADP
fnp-3271	38	41	a	a	DET
fnp-3271	38	42	small	small	ADJ
fnp-3271	38	43	subset	subset	NOUN
fnp-3271	38	44	of	of	ADP
fnp-3271	38	45	these	these	DET
fnp-3271	38	46	tumors	tumor	NOUN
fnp-3271	38	47	and	and	CCONJ
fnp-3271	38	48	signify	signify	VERB
fnp-3271	38	49	worse	bad	ADJ
fnp-3271	38	50	prognosis	prognosis	NOUN
fnp-3271	38	51	.	.	PUNCT
fnp-3271	39	1	topic	topic	NOUN
fnp-3271	39	2	2	2	NUM
fnp-3271	39	3	.	.	X
fnp-3271	39	4	molecular	molecular	ADJ
fnp-3271	39	5	landscape	landscape	NOUN
fnp-3271	39	6	of	of	ADP
fnp-3271	39	7	pediatric	pediatric	ADJ
fnp-3271	39	8	low	low	ADJ
fnp-3271	39	9	-	-	PUNCT
fnp-3271	39	10	grade	grade	NOUN
fnp-3271	39	11	gliomas	glioma	NOUN
fnp-3271	39	12	[	[	X
fnp-3271	39	13	2	2	NUM
fnp-3271	39	14	]	]	PUNCT
fnp-3271	39	15	ryall	ryall	NOUN
fnp-3271	39	16	s	s	X
fnp-3271	39	17	et	et	NOUN
fnp-3271	39	18	al	al	PROPN
fnp-3271	39	19	(	(	PUNCT
fnp-3271	39	20	with	with	ADP
fnp-3271	39	21	tabori	tabori	NOUN
fnp-3271	39	22	u	u	NOUN
fnp-3271	39	23	and	and	CCONJ
fnp-3271	39	24	hawkins	hawkins	PROPN
fnp-3271	39	25	c	c	PROPN
fnp-3271	39	26	as	as	ADP
fnp-3271	39	27	co	co	ADJ
fnp-3271	39	28	-	-	ADJ
fnp-3271	39	29	senior	senior	ADJ
fnp-3271	39	30	authors	author	NOUN
fnp-3271	39	31	)	)	PUNCT
fnp-3271	39	32	published	publish	VERB
fnp-3271	39	33	a	a	DET
fnp-3271	39	34	paper	paper	NOUN
fnp-3271	39	35	in	in	ADP
fnp-3271	39	36	cancer	cancer	NOUN
fnp-3271	39	37	cell	cell	NOUN
fnp-3271	39	38	reporting	report	VERB
fnp-3271	39	39	the	the	DET
fnp-3271	39	40	results	result	NOUN
fnp-3271	39	41	of	of	ADP
fnp-3271	39	42	combined	combined	ADJ
fnp-3271	39	43	clinical	clinical	ADJ
fnp-3271	39	44	,	,	PUNCT
fnp-3271	39	45	morphological	morphological	ADJ
fnp-3271	39	46	and	and	CCONJ
fnp-3271	39	47	molecular	molecular	ADJ
fnp-3271	39	48	profiling	profiling	NOUN
fnp-3271	39	49	of	of	ADP
fnp-3271	39	50	>	>	X
fnp-3271	39	51	1000	1000	NUM
fnp-3271	39	52	well	well	ADV
fnp-3271	39	53	-	-	PUNCT
fnp-3271	39	54	annotated	annotate	VERB
fnp-3271	39	55	,	,	PUNCT
fnp-3271	39	56	pediatric	pediatric	ADJ
fnp-3271	39	57	low	low	ADJ
fnp-3271	39	58	-	-	PUNCT
fnp-3271	39	59	grade	grade	NOUN
fnp-3271	39	60	gliomas	glioma	NOUN
fnp-3271	39	61	(	(	PUNCT
fnp-3271	39	62	plggs	plggs	PROPN
fnp-3271	39	63	)	)	PUNCT
fnp-3271	39	64	with	with	ADP
fnp-3271	39	65	extensive	extensive	ADJ
fnp-3271	39	66	clinical	clinical	ADJ
fnp-3271	39	67	follow	follow	NOUN
fnp-3271	39	68	-	-	PUNCT
fnp-3271	39	69	up	up	NOUN
fnp-3271	39	70	.	.	PUNCT
fnp-3271	40	1	the	the	DET
fnp-3271	40	2	vast	vast	ADJ
fnp-3271	40	3	majority	majority	NOUN
fnp-3271	40	4	of	of	ADP
fnp-3271	40	5	the	the	DET
fnp-3271	40	6	cases	case	NOUN
fnp-3271	40	7	that	that	PRON
fnp-3271	40	8	could	could	AUX
fnp-3271	40	9	be	be	AUX
fnp-3271	40	10	adequately	adequately	ADV
fnp-3271	40	11	analyzed	analyze	VERB
fnp-3271	40	12	at	at	ADP
fnp-3271	40	13	the	the	DET
fnp-3271	40	14	molecular	molecular	ADJ
fnp-3271	40	15	level	level	NOUN
fnp-3271	40	16	were	be	AUX
fnp-3271	40	17	found	find	VERB
fnp-3271	40	18	to	to	PART
fnp-3271	40	19	harbor	harbor	VERB
fnp-3271	40	20	a	a	DET
fnp-3271	40	21	driver	driver	NOUN
fnp-3271	40	22	alteration	alteration	NOUN
fnp-3271	40	23	leading	lead	VERB
fnp-3271	40	24	to	to	ADP
fnp-3271	40	25	activation	activation	NOUN
fnp-3271	40	26	of	of	ADP
fnp-3271	40	27	the	the	DET
fnp-3271	40	28	ras	ras	PROPN
fnp-3271	40	29	/	/	SYM
fnp-3271	40	30	mapk	mapk	NOUN
fnp-3271	40	31	pathway	pathway	NOUN
fnp-3271	40	32	,	,	PUNCT
fnp-3271	40	33	while	while	SCONJ
fnp-3271	40	34	those	those	PRON
fnp-3271	40	35	without	without	ADP
fnp-3271	40	36	an	an	DET
fnp-3271	40	37	identified	identify	VERB
fnp-3271	40	38	alteration	alteration	NOUN
fnp-3271	40	39	often	often	ADV
fnp-3271	40	40	showed	show	VERB
fnp-3271	40	41	upregulation	upregulation	NOUN
fnp-3271	40	42	of	of	ADP
fnp-3271	40	43	this	this	DET
fnp-3271	40	44	pathway	pathway	NOUN
fnp-3271	40	45	as	as	ADV
fnp-3271	40	46	well	well	ADV
fnp-3271	40	47	.	.	PUNCT
fnp-3271	41	1	based	base	VERB
fnp-3271	41	2	on	on	ADP
fnp-3271	41	3	the	the	DET
fnp-3271	41	4	type	type	NOUN
fnp-3271	41	5	of	of	ADP
fnp-3271	41	6	molecular	molecular	ADJ
fnp-3271	41	7	alteration	alteration	NOUN
fnp-3271	41	8	,	,	PUNCT
fnp-3271	41	9	plggs	plgg	NOUN
fnp-3271	41	10	could	could	AUX
fnp-3271	41	11	be	be	AUX
fnp-3271	41	12	broadly	broadly	ADV
fnp-3271	41	13	classified	classify	VERB
fnp-3271	41	14	in	in	ADP
fnp-3271	41	15	different	different	ADJ
fnp-3271	41	16	classes	class	NOUN
fnp-3271	41	17	:	:	PUNCT
fnp-3271	41	18	rearrangement	rearrangement	NOUN
fnp-3271	41	19	-	-	PUNCT
fnp-3271	41	20	driven	drive	VERB
fnp-3271	41	21	/	/	SYM
fnp-3271	41	22	fusion	fusion	NOUN
fnp-3271	41	23	-	-	PUNCT
fnp-3271	41	24	positive	positive	ADJ
fnp-3271	41	25	tumors	tumor	NOUN
fnp-3271	41	26	versus	versus	ADP
fnp-3271	41	27	tumors	tumor	NOUN
fnp-3271	41	28	with	with	ADP
fnp-3271	41	29	a	a	DET
fnp-3271	41	30	single	single	ADJ
fnp-3271	41	31	-	-	PUNCT
fnp-3271	41	32	nucleotide	nucleotide	NOUN
fnp-3271	41	33	variant	variant	NOUN
fnp-3271	41	34	(	(	PUNCT
fnp-3271	41	35	snv	snv	PROPN
fnp-3271	41	36	)	)	PUNCT
fnp-3271	41	37	.	.	PUNCT
fnp-3271	42	1	tumors	tumor	NOUN
fnp-3271	42	2	in	in	ADP
fnp-3271	42	3	the	the	DET
fnp-3271	42	4	former	former	ADJ
fnp-3271	42	5	category	category	NOUN
fnp-3271	42	6	were	be	AUX
fnp-3271	42	7	diagnosed	diagnose	VERB
fnp-3271	42	8	at	at	ADP
fnp-3271	42	9	a	a	DET
fnp-3271	42	10	younger	young	ADJ
fnp-3271	42	11	age	age	NOUN
fnp-3271	42	12	,	,	PUNCT
fnp-3271	42	13	enriched	enrich	VERB
fnp-3271	42	14	for	for	ADP
fnp-3271	42	15	who	who	PRON
fnp-3271	42	16	grade	grade	NOUN
fnp-3271	42	17	i	i	PRON
fnp-3271	42	18	histology	histology	NOUN
fnp-3271	42	19	,	,	PUNCT
fnp-3271	42	20	progressed	progress	VERB
fnp-3271	42	21	infrequently	infrequently	ADV
fnp-3271	42	22	,	,	PUNCT
fnp-3271	42	23	and	and	CCONJ
fnp-3271	42	24	rarely	rarely	ADV
fnp-3271	42	25	resulted	result	VERB
fnp-3271	42	26	in	in	ADP
fnp-3271	42	27	death	death	NOUN
fnp-3271	42	28	as	as	SCONJ
fnp-3271	42	29	compared	compare	VERB
fnp-3271	42	30	to	to	ADP
fnp-3271	42	31	tumors	tumor	NOUN
fnp-3271	42	32	in	in	ADP
fnp-3271	42	33	the	the	DET
fnp-3271	42	34	latter	latter	ADJ
fnp-3271	42	35	category	category	NOUN
fnp-3271	42	36	.	.	PUNCT
fnp-3271	43	1	correlation	correlation	NOUN
fnp-3271	43	2	of	of	ADP
fnp-3271	43	3	type	type	NOUN
fnp-3271	43	4	of	of	ADP
fnp-3271	43	5	molecular	molecular	ADJ
fnp-3271	43	6	alteration	alteration	NOUN
fnp-3271	43	7	with	with	ADP
fnp-3271	43	8	outcome	outcome	NOUN
fnp-3271	43	9	(	(	PUNCT
fnp-3271	43	10	incidence	incidence	NOUN
fnp-3271	43	11	of	of	ADP
fnp-3271	43	12	disease	disease	NOUN
fnp-3271	43	13	progression	progression	NOUN
fnp-3271	43	14	or	or	CCONJ
fnp-3271	43	15	death	death	NOUN
fnp-3271	43	16	)	)	PUNCT
fnp-3271	43	17	allowed	allow	VERB
fnp-3271	43	18	for	for	ADP
fnp-3271	43	19	stratification	stratification	NOUN
fnp-3271	43	20	of	of	ADP
fnp-3271	43	21	plggs	plgg	NOUN
fnp-3271	43	22	into	into	ADP
fnp-3271	43	23	three	three	NUM
fnp-3271	43	24	risk	risk	NOUN
fnp-3271	43	25	categories	category	NOUN
fnp-3271	43	26	:	:	PUNCT
fnp-3271	43	27	low	low	ADJ
fnp-3271	43	28	risk	risk	NOUN
fnp-3271	43	29	(	(	PUNCT
fnp-3271	43	30	braf	braf	NOUN
fnp-3271	43	31	fusions	fusion	NOUN
fnp-3271	43	32	,	,	PUNCT
fnp-3271	43	33	nf1	nf1	NOUN
fnp-3271	43	34	alterations	alteration	NOUN
fnp-3271	43	35	,	,	PUNCT
fnp-3271	43	36	fgfr2	fgfr2	ADJ
fnp-3271	43	37	fusions	fusion	NOUN
fnp-3271	43	38	,	,	PUNCT
fnp-3271	43	39	myb	myb	NOUN
fnp-3271	43	40	/	/	SYM
fnp-3271	43	41	mybl1	mybl1	NOUN
fnp-3271	43	42	rearrangements	rearrangement	NOUN
fnp-3271	43	43	,	,	PUNCT
fnp-3271	43	44	fgfr1	fgfr1	PROPN
fnp-3271	43	45	tyrosine	tyrosine	PROPN
fnp-3271	43	46	kinase	kinase	PROPN
fnp-3271	43	47	duplications	duplication	NOUN
fnp-3271	43	48	,	,	PUNCT
fnp-3271	43	49	fgfr1	fgfr1	NOUN
fnp-3271	43	50	-	-	PUNCT
fnp-3271	43	51	tacc1	tacc1	NOUN
fnp-3271	43	52	fusion	fusion	NOUN
fnp-3271	43	53	)	)	PUNCT
fnp-3271	43	54	;	;	PUNCT
fnp-3271	43	55	intermediate	intermediate	ADJ
fnp-3271	43	56	risk	risk	NOUN
fnp-3271	43	57	(	(	PUNCT
fnp-3271	43	58	braf	braf	NOUN
fnp-3271	43	59	p.v600e	p.v600e	PROPN
fnp-3271	43	60	,	,	PUNCT
fnp-3271	43	61	idh1	idh1	PROPN
fnp-3271	43	62	p.r132h	p.r132h	PROPN
fnp-3271	43	63	,	,	PUNCT
fnp-3271	43	64	fgfr1	fgfr1	PROPN
fnp-3271	43	65	snv	snv	PROPN
fnp-3271	43	66	,	,	PUNCT
fnp-3271	43	67	met	meet	VERB
fnp-3271	43	68	snv	snv	PROPN
fnp-3271	43	69	)	)	PUNCT
fnp-3271	43	70	;	;	PUNCT
fnp-3271	43	71	and	and	CCONJ
fnp-3271	43	72	high	high	ADJ
fnp-3271	43	73	risk	risk	NOUN
fnp-3271	43	74	(	(	PUNCT
fnp-3271	43	75	braf	braf	NOUN
fnp-3271	43	76	p.v600e	p.v600e	X
fnp-3271	43	77	+	+	CCONJ
fnp-3271	43	78	cdkn2a	cdkn2a	PROPN
fnp-3271	43	79	deletion	deletion	NOUN
fnp-3271	43	80	,	,	PUNCT
fnp-3271	43	81	h3.3	h3.3	NOUN
fnp-3271	43	82	p.k27	p.k27	PROPN
fnp-3271	43	83	m	m	NOUN
fnp-3271	43	84	)	)	PUNCT
fnp-3271	43	85	.	.	PUNCT
fnp-3271	44	1	additionally	additionally	ADV
fnp-3271	44	2	,	,	PUNCT
fnp-3271	44	3	a	a	DET
fnp-3271	44	4	small	small	ADJ
fnp-3271	44	5	,	,	PUNCT
fnp-3271	44	6	remaining	remain	VERB
fnp-3271	44	7	group	group	NOUN
fnp-3271	44	8	of	of	ADP
fnp-3271	44	9	‘	'	PUNCT
fnp-3271	44	10	unknown	unknown	ADJ
fnp-3271	44	11	risk	risk	NOUN
fnp-3271	44	12	’	'	PUNCT
fnp-3271	44	13	was	be	AUX
fnp-3271	44	14	found	find	VERB
fnp-3271	44	15	with	with	ADP
fnp-3271	44	16	fusions	fusion	NOUN
fnp-3271	44	17	of	of	ADP
fnp-3271	44	18	or	or	CCONJ
fnp-3271	44	19	snvs	snvs	NOUN
fnp-3271	44	20	in	in	ADP
fnp-3271	44	21	other	other	ADJ
fnp-3271	44	22	genes	gene	NOUN
fnp-3271	44	23	.	.	PUNCT
fnp-3271	45	1	importantly	importantly	ADV
fnp-3271	45	2	,	,	PUNCT
fnp-3271	45	3	while	while	SCONJ
fnp-3271	45	4	most	most	ADJ
fnp-3271	45	5	plggs	plgg	NOUN
fnp-3271	45	6	in	in	ADP
fnp-3271	45	7	children	child	NOUN
fnp-3271	45	8	with	with	ADP
fnp-3271	45	9	the	the	DET
fnp-3271	45	10	genetic	genetic	ADJ
fnp-3271	45	11	pre	pre	ADJ
fnp-3271	45	12	-	-	ADJ
fnp-3271	45	13	disposition	disposition	ADJ
fnp-3271	45	14	disorder	disorder	NOUN
fnp-3271	45	15	nf1	nf1	NOUN
fnp-3271	45	16	occurred	occur	VERB
fnp-3271	45	17	as	as	ADP
fnp-3271	45	18	optic	optic	ADJ
fnp-3271	45	19	pathway	pathway	NOUN
fnp-3271	45	20	glioma	glioma	NOUN
fnp-3271	45	21	and	and	CCONJ
fnp-3271	45	22	had	have	VERB
fnp-3271	45	23	a	a	DET
fnp-3271	45	24	good	good	ADJ
fnp-3271	45	25	prognosis	prognosis	NOUN
fnp-3271	45	26	,	,	PUNCT
fnp-3271	45	27	nf1	nf1	NOUN
fnp-3271	45	28	plggs	plggs	NOUN
fnp-3271	45	29	arising	arise	VERB
fnp-3271	45	30	outside	outside	ADP
fnp-3271	45	31	the	the	DET
fnp-3271	45	32	optic	optic	ADJ
fnp-3271	45	33	pathway	pathway	NOUN
fnp-3271	45	34	had	have	VERB
fnp-3271	45	35	significantly	significantly	ADV
fnp-3271	45	36	worse	bad	ADJ
fnp-3271	45	37	overall	overall	ADJ
fnp-3271	45	38	and	and	CCONJ
fnp-3271	45	39	progression	progression	NOUN
fnp-3271	45	40	-	-	PUNCT
fnp-3271	45	41	free	free	ADJ
fnp-3271	45	42	survival	survival	NOUN
fnp-3271	45	43	.	.	PUNCT
fnp-3271	46	1	also	also	ADV
fnp-3271	46	2	,	,	PUNCT
fnp-3271	46	3	the	the	DET
fnp-3271	46	4	most	most	ADV
fnp-3271	46	5	common	common	ADJ
fnp-3271	46	6	kiaa1549	kiaa1549	PROPN
fnp-3271	46	7	-	-	PUNCT
fnp-3271	46	8	braf	braf	NOUN
fnp-3271	46	9	fusion	fusion	NOUN
fnp-3271	46	10	,	,	PUNCT
fnp-3271	46	11	i.e.	i.e.	X
fnp-3271	46	12	16:09	16:09	NUM
fnp-3271	46	13	(	(	PUNCT
fnp-3271	46	14	involving	involve	VERB
fnp-3271	46	15	exon	exon	PROPN
fnp-3271	46	16	16	16	NUM
fnp-3271	46	17	of	of	ADP
fnp-3271	46	18	kiaa1549	kiaa1549	PROPN
fnp-3271	46	19	and	and	CCONJ
fnp-3271	46	20	exon	exon	NOUN
fnp-3271	46	21	9	9	NUM
fnp-3271	46	22	of	of	ADP
fnp-3271	46	23	braf	braf	NOUN
fnp-3271	46	24	)	)	PUNCT
fnp-3271	46	25	,	,	PUNCT
fnp-3271	46	26	was	be	AUX
fnp-3271	46	27	found	find	VERB
fnp-3271	46	28	to	to	PART
fnp-3271	46	29	be	be	AUX
fnp-3271	46	30	associated	associate	VERB
fnp-3271	46	31	with	with	ADP
fnp-3271	46	32	cerebellar	cerebellar	ADJ
fnp-3271	46	33	location	location	NOUN
fnp-3271	46	34	and	and	CCONJ
fnp-3271	46	35	good	good	ADJ
fnp-3271	46	36	prognosis	prognosis	NOUN
fnp-3271	46	37	.	.	PUNCT
fnp-3271	47	1	in	in	ADP
fnp-3271	47	2	contrast	contrast	NOUN
fnp-3271	47	3	,	,	PUNCT
fnp-3271	47	4	the	the	DET
fnp-3271	47	5	kiaa1549	kiaa1549	PROPN
fnp-3271	47	6	-	-	PUNCT
fnp-3271	47	7	braf	braf	PROPN
fnp-3271	47	8	15:09	15:09	NUM
fnp-3271	47	9	fusion	fusion	NOUN
fnp-3271	47	10	was	be	AUX
fnp-3271	47	11	the	the	DET
fnp-3271	47	12	only	only	ADJ
fnp-3271	47	13	fusion	fusion	NOUN
fnp-3271	47	14	type	type	NOUN
fnp-3271	47	15	seen	see	VERB
fnp-3271	47	16	in	in	ADP
fnp-3271	47	17	hemispheric	hemispheric	ADJ
fnp-3271	47	18	tumors	tumor	NOUN
fnp-3271	47	19	,	,	PUNCT
fnp-3271	47	20	the	the	DET
fnp-3271	47	21	primary	primary	ADJ
fnp-3271	47	22	fusion	fusion	NOUN
fnp-3271	47	23	found	find	VERB
fnp-3271	47	24	in	in	ADP
fnp-3271	47	25	tumors	tumor	NOUN
fnp-3271	47	26	with	with	ADP
fnp-3271	47	27	‘	'	PUNCT
fnp-3271	47	28	extensive	extensive	ADJ
fnp-3271	47	29	dissemination	dissemination	NOUN
fnp-3271	47	30	’	'	PUNCT
fnp-3271	47	31	,	,	PUNCT
fnp-3271	47	32	and	and	CCONJ
fnp-3271	47	33	associated	associate	VERB
fnp-3271	47	34	with	with	ADP
fnp-3271	47	35	a	a	DET
fnp-3271	47	36	worse	bad	ADJ
fnp-3271	47	37	progression	progression	NOUN
fnp-3271	47	38	-	-	PUNCT
fnp-3271	47	39	free	free	ADJ
fnp-3271	47	40	survival	survival	NOUN
fnp-3271	47	41	.	.	PUNCT
fnp-3271	48	1	these	these	DET
fnp-3271	48	2	findings	finding	NOUN
fnp-3271	48	3	indeed	indeed	ADV
fnp-3271	48	4	provide	provide	VERB
fnp-3271	48	5	very	very	ADV
fnp-3271	48	6	helpful	helpful	ADJ
fnp-3271	48	7	guidance	guidance	NOUN
fnp-3271	48	8	for	for	ADP
fnp-3271	48	9	the	the	DET
fnp-3271	48	10	prognostication	prognostication	NOUN
fnp-3271	48	11	and	and	CCONJ
fnp-3271	48	12	clinical	clinical	ADJ
fnp-3271	48	13	management	management	NOUN
fnp-3271	48	14	of	of	ADP
fnp-3271	48	15	patients	patient	NOUN
fnp-3271	48	16	with	with	ADP
fnp-3271	48	17	plggs	plggs	PROPN
fnp-3271	48	18	(	(	PUNCT
fnp-3271	48	19	e.g.	e.g.	ADV
fnp-3271	48	20	‘	'	PUNCT
fnp-3271	48	21	watch	watch	VERB
fnp-3271	48	22	&	&	CCONJ
fnp-3271	48	23	wait	wait	VERB
fnp-3271	48	24	’	'	PUNCT
fnp-3271	48	25	for	for	ADP
fnp-3271	48	26	low	low	ADJ
fnp-3271	48	27	-	-	PUNCT
fnp-3271	48	28	risk	risk	NOUN
fnp-3271	48	29	tumors	tumor	NOUN
fnp-3271	48	30	versus	versus	ADP
fnp-3271	48	31	a	a	DET
fnp-3271	48	32	more	more	ADV
fnp-3271	48	33	aggressive	aggressive	ADJ
fnp-3271	48	34	approach	approach	NOUN
fnp-3271	48	35	for	for	ADP
fnp-3271	48	36	intermediate	intermediate	ADJ
fnp-3271	48	37	and	and	CCONJ
fnp-3271	48	38	high	high	ADJ
fnp-3271	48	39	-	-	PUNCT
fnp-3271	48	40	risk	risk	NOUN
fnp-3271	48	41	tumors	tumor	NOUN
fnp-3271	48	42	)	)	PUNCT
fnp-3271	48	43	.	.	PUNCT
fnp-3271	49	1	obviously	obviously	ADV
fnp-3271	49	2	,	,	PUNCT
fnp-3271	49	3	for	for	ADP
fnp-3271	49	4	individual	individual	ADJ
fnp-3271	49	5	patients	patient	NOUN
fnp-3271	49	6	,	,	PUNCT
fnp-3271	49	7	such	such	ADJ
fnp-3271	49	8	information	information	NOUN
fnp-3271	49	9	should	should	AUX
fnp-3271	49	10	be	be	AUX
fnp-3271	49	11	evaluated	evaluate	VERB
fnp-3271	49	12	in	in	ADP
fnp-3271	49	13	the	the	DET
fnp-3271	49	14	context	context	NOUN
fnp-3271	49	15	of	of	ADP
fnp-3271	49	16	the	the	DET
fnp-3271	49	17	clinical	clinical	ADJ
fnp-3271	49	18	situation	situation	NOUN
fnp-3271	49	19	,	,	PUNCT
fnp-3271	49	20	other	other	ADJ
fnp-3271	49	21	molecular	molecular	ADJ
fnp-3271	49	22	findings	finding	NOUN
fnp-3271	49	23	,	,	PUNCT
fnp-3271	49	24	and	and	CCONJ
fnp-3271	49	25	the	the	DET
fnp-3271	49	26	exact	exact	NOUN
fnp-3271	49	27	who	who	PRON
fnp-3271	49	28	diagnosis	diagnosis	NOUN
fnp-3271	49	29	(	(	PUNCT
fnp-3271	49	30	figure	figure	NOUN
fnp-3271	49	31	1	1	NUM
fnp-3271	49	32	)	)	PUNCT
fnp-3271	49	33	.	.	PUNCT
fnp-3271	50	1	fig	fig	NOUN
fnp-3271	50	2	.	.	PUNCT
fnp-3271	51	1	1	1	X
fnp-3271	51	2	.	.	X
fnp-3271	51	3	kiaa	kiaa	VERB
fnp-3271	51	4	-	-	PUNCT
fnp-3271	51	5	braf1549	braf1549	PROPN
fnp-3271	51	6	duplication	duplication	NOUN
fnp-3271	51	7	(	(	PUNCT
fnp-3271	51	8	and	and	CCONJ
fnp-3271	51	9	fusion	fusion	NOUN
fnp-3271	51	10	)	)	PUNCT
fnp-3271	51	11	as	as	SCONJ
fnp-3271	51	12	seen	see	VERB
fnp-3271	51	13	in	in	ADP
fnp-3271	51	14	the	the	DET
fnp-3271	51	15	copy	copy	NOUN
fnp-3271	51	16	number	number	NOUN
fnp-3271	51	17	variation	variation	NOUN
fnp-3271	51	18	(	(	PUNCT
fnp-3271	51	19	cnv)-profile	cnv)-profile	ADJ
fnp-3271	51	20	of	of	ADP
fnp-3271	51	21	a	a	DET
fnp-3271	51	22	pilocytic	pilocytic	ADJ
fnp-3271	51	23	astrocytoma	astrocytoma	NOUN
fnp-3271	51	24	(	(	PUNCT
fnp-3271	51	25	a	a	NOUN
fnp-3271	51	26	)	)	PUNCT
fnp-3271	51	27	and	and	CCONJ
fnp-3271	51	28	a	a	DET
fnp-3271	51	29	diffuse	diffuse	NOUN
fnp-3271	51	30	leptomeningeal	leptomeningeal	ADJ
fnp-3271	51	31	glioneuronal	glioneuronal	ADJ
fnp-3271	51	32	tumor	tumor	NOUN
fnp-3271	51	33	(	(	PUNCT
fnp-3271	51	34	dlgnt	dlgnt	PROPN
fnp-3271	51	35	)	)	PUNCT
fnp-3271	51	36	(	(	PUNCT
fnp-3271	51	37	b	b	NOUN
fnp-3271	51	38	)	)	PUNCT
fnp-3271	51	39	.	.	PUNCT
fnp-3271	52	1	a	a	DET
fnp-3271	52	2	tandem	tandem	NOUN
fnp-3271	52	3	duplication	duplication	NOUN
fnp-3271	52	4	of	of	ADP
fnp-3271	52	5	chromosome	chromosome	NOUN
fnp-3271	52	6	7q34	7q34	NUM
fnp-3271	52	7	,	,	PUNCT
fnp-3271	52	8	indicative	indicative	ADJ
fnp-3271	52	9	of	of	ADP
fnp-3271	52	10	the	the	DET
fnp-3271	52	11	kiaa1549	kiaa1549	PROPN
fnp-3271	52	12	-	-	PUNCT
fnp-3271	52	13	braf	braf	NOUN
fnp-3271	52	14	fusion	fusion	NOUN
fnp-3271	52	15	,	,	PUNCT
fnp-3271	52	16	is	be	AUX
fnp-3271	52	17	a	a	DET
fnp-3271	52	18	frequent	frequent	ADJ
fnp-3271	52	19	event	event	NOUN
fnp-3271	52	20	in	in	ADP
fnp-3271	52	21	pilocytic	pilocytic	ADJ
fnp-3271	52	22	astrocytomas	astrocytoma	NOUN
fnp-3271	52	23	and	and	CCONJ
fnp-3271	52	24	dlgnts	dlgnt	NOUN
fnp-3271	52	25	.	.	PUNCT
fnp-3271	53	1	such	such	DET
fnp-3271	53	2	a	a	DET
fnp-3271	53	3	duplication	duplication	NOUN
fnp-3271	53	4	is	be	AUX
fnp-3271	53	5	generally	generally	ADV
fnp-3271	53	6	clearly	clearly	ADV
fnp-3271	53	7	visible	visible	ADJ
fnp-3271	53	8	as	as	ADP
fnp-3271	53	9	a	a	DET
fnp-3271	53	10	relatively	relatively	ADV
fnp-3271	53	11	high	high	ADJ
fnp-3271	53	12	position	position	NOUN
fnp-3271	53	13	for	for	ADP
fnp-3271	53	14	this	this	DET
fnp-3271	53	15	region	region	NOUN
fnp-3271	53	16	(	(	PUNCT
fnp-3271	53	17	indicated	indicate	VERB
fnp-3271	53	18	by	by	ADP
fnp-3271	53	19	arrows	arrow	NOUN
fnp-3271	53	20	in	in	ADP
fnp-3271	53	21	a	a	PRON
fnp-3271	53	22	and	and	CCONJ
fnp-3271	53	23	b	b	NOUN
fnp-3271	53	24	)	)	PUNCT
fnp-3271	53	25	compared	compare	VERB
fnp-3271	53	26	to	to	ADP
fnp-3271	53	27	the	the	DET
fnp-3271	53	28	rest	rest	NOUN
fnp-3271	53	29	of	of	ADP
fnp-3271	53	30	chromosome	chromosome	NOUN
fnp-3271	53	31	7	7	NUM
fnp-3271	53	32	in	in	ADP
fnp-3271	53	33	the	the	DET
fnp-3271	53	34	detailed	detailed	ADJ
fnp-3271	53	35	cnv	cnv	NOUN
fnp-3271	53	36	profiles	profile	NOUN
fnp-3271	53	37	that	that	PRON
fnp-3271	53	38	can	can	AUX
fnp-3271	53	39	be	be	AUX
fnp-3271	53	40	obtained	obtain	VERB
fnp-3271	53	41	using	use	VERB
fnp-3271	53	42	e.g.	e.g.	ADV
fnp-3271	53	43	methylome	methylome	ADJ
fnp-3271	53	44	profiling	profiling	NOUN
fnp-3271	53	45	[	[	X
fnp-3271	53	46	55	55	NUM
fnp-3271	53	47	]	]	PUNCT
fnp-3271	53	48	.	.	PUNCT
fnp-3271	54	1	ryall	ryall	PROPN
fnp-3271	54	2	s	s	PART
fnp-3271	54	3	et	et	AUX
fnp-3271	54	4	al	al	PROPN
fnp-3271	54	5	propose	propose	VERB
fnp-3271	54	6	disease	disease	NOUN
fnp-3271	54	7	stratification	stratification	NOUN
fnp-3271	54	8	of	of	ADP
fnp-3271	54	9	pediatric	pediatric	ADJ
fnp-3271	54	10	low	low	ADJ
fnp-3271	54	11	-	-	PUNCT
fnp-3271	54	12	grade	grade	NOUN
fnp-3271	54	13	gliomas	glioma	NOUN
fnp-3271	54	14	(	(	PUNCT
fnp-3271	54	15	plggs	plggs	PROPN
fnp-3271	54	16	)	)	PUNCT
fnp-3271	54	17	based	base	VERB
fnp-3271	54	18	on	on	ADP
fnp-3271	54	19	the	the	DET
fnp-3271	54	20	type	type	NOUN
fnp-3271	54	21	of	of	ADP
fnp-3271	54	22	molecular	molecular	ADJ
fnp-3271	54	23	alteration(s	alteration(s	NOUN
fnp-3271	54	24	)	)	PUNCT
fnp-3271	54	25	in	in	ADP
fnp-3271	54	26	the	the	DET
fnp-3271	54	27	tumor	tumor	NOUN
fnp-3271	54	28	,	,	PUNCT
fnp-3271	54	29	with	with	ADP
fnp-3271	54	30	most	most	ADJ
fnp-3271	54	31	kiaa1549	kiaa1549	NOUN
fnp-3271	54	32	-	-	PUNCT
fnp-3271	54	33	braf	braf	NOUN
fnp-3271	54	34	fusion	fusion	NOUN
fnp-3271	54	35	-	-	PUNCT
fnp-3271	54	36	positive	positive	ADJ
fnp-3271	54	37	tumors	tumor	NOUN
fnp-3271	54	38	belonging	belong	VERB
fnp-3271	54	39	to	to	ADP
fnp-3271	54	40	the	the	DET
fnp-3271	54	41	low	low	ADJ
fnp-3271	54	42	-	-	PUNCT
fnp-3271	54	43	risk	risk	NOUN
fnp-3271	54	44	category	category	NOUN
fnp-3271	54	45	[	[	X
fnp-3271	54	46	2	2	NUM
fnp-3271	54	47	]	]	PUNCT
fnp-3271	54	48	.	.	PUNCT
fnp-3271	55	1	it	it	PRON
fnp-3271	55	2	is	be	AUX
fnp-3271	55	3	important	important	ADJ
fnp-3271	55	4	to	to	PART
fnp-3271	55	5	put	put	VERB
fnp-3271	55	6	such	such	ADJ
fnp-3271	55	7	information	information	NOUN
fnp-3271	55	8	in	in	ADP
fnp-3271	55	9	perspective	perspective	NOUN
fnp-3271	55	10	of	of	ADP
fnp-3271	55	11	clinical	clinical	ADJ
fnp-3271	55	12	and	and	CCONJ
fnp-3271	55	13	other	other	ADJ
fnp-3271	55	14	molecular	molecular	ADJ
fnp-3271	55	15	findings	finding	NOUN
fnp-3271	55	16	and	and	CCONJ
fnp-3271	55	17	of	of	ADP
fnp-3271	55	18	the	the	DET
fnp-3271	55	19	who	who	PRON
fnp-3271	55	20	diagnosis	diagnosis	NOUN
fnp-3271	55	21	of	of	ADP
fnp-3271	55	22	the	the	DET
fnp-3271	55	23	individual	individual	ADJ
fnp-3271	55	24	patient	patient	NOUN
fnp-3271	55	25	.	.	PUNCT
fnp-3271	56	1	for	for	ADP
fnp-3271	56	2	example	example	NOUN
fnp-3271	56	3	,	,	PUNCT
fnp-3271	56	4	all	all	DET
fnp-3271	56	5	dlgnts	dlgnt	NOUN
fnp-3271	56	6	typically	typically	ADV
fnp-3271	56	7	show	show	VERB
fnp-3271	56	8	loss	loss	NOUN
fnp-3271	56	9	of	of	ADP
fnp-3271	56	10	chromosome	chromosome	NOUN
fnp-3271	56	11	1p	1p	NUM
fnp-3271	56	12	.	.	PUNCT
fnp-3271	57	1	the	the	DET
fnp-3271	57	2	cnv	cnv	PROPN
fnp-3271	57	3	profile	profile	NOUN
fnp-3271	57	4	of	of	ADP
fnp-3271	57	5	the	the	DET
fnp-3271	57	6	dlgnt	dlgnt	VERB
fnp-3271	57	7	depicted	depict	VERB
fnp-3271	57	8	in	in	ADP
fnp-3271	57	9	b	b	NOUN
fnp-3271	57	10	additionally	additionally	ADV
fnp-3271	57	11	shows	show	VERB
fnp-3271	57	12	gain	gain	NOUN
fnp-3271	57	13	of	of	ADP
fnp-3271	57	14	chromosome	chromosome	NOUN
fnp-3271	57	15	arm	arm	NOUN
fnp-3271	57	16	1q	1q	NOUN
fnp-3271	57	17	and	and	CCONJ
fnp-3271	57	18	of	of	ADP
fnp-3271	57	19	chromosome	chromosome	NOUN
fnp-3271	57	20	8	8	NUM
fnp-3271	57	21	,	,	PUNCT
fnp-3271	57	22	two	two	NUM
fnp-3271	57	23	features	feature	NOUN
fnp-3271	57	24	that	that	PRON
fnp-3271	57	25	fit	fit	VERB
fnp-3271	57	26	very	very	ADV
fnp-3271	57	27	well	well	ADV
fnp-3271	57	28	with	with	ADP
fnp-3271	57	29	the	the	DET
fnp-3271	57	30	more	more	ADV
fnp-3271	57	31	aggressive	aggressive	ADJ
fnp-3271	57	32	‘	'	PUNCT
fnp-3271	57	33	methylation	methylation	NOUN
fnp-3271	57	34	class	class	NOUN
fnp-3271	57	35	2	2	NUM
fnp-3271	57	36	’	'	PUNCT
fnp-3271	57	37	of	of	ADP
fnp-3271	57	38	these	these	DET
fnp-3271	57	39	tumors	tumor	NOUN
fnp-3271	58	1	[	[	X
fnp-3271	58	2	56	56	NUM
fnp-3271	58	3	]	]	PUNCT
fnp-3271	58	4	.	.	PUNCT
fnp-3271	59	1	interestingly	interestingly	ADV
fnp-3271	59	2	,	,	PUNCT
fnp-3271	59	3	rt	rt	ADJ
fnp-3271	59	4	-	-	PUNCT
fnp-3271	59	5	pcr	pcr	NOUN
fnp-3271	59	6	analysis	analysis	NOUN
fnp-3271	59	7	of	of	ADP
fnp-3271	59	8	this	this	PRON
fnp-3271	59	9	dlgnt	dlgnt	VERB
fnp-3271	59	10	revealed	reveal	VERB
fnp-3271	59	11	the	the	DET
fnp-3271	59	12	15:09	15:09	NUM
fnp-3271	59	13	kiaa1549	kiaa1549	PROPN
fnp-3271	59	14	-	-	PUNCT
fnp-3271	59	15	braf	braf	NOUN
fnp-3271	59	16	fusion	fusion	NOUN
fnp-3271	59	17	,	,	PUNCT
fnp-3271	59	18	i.e.	i.e.	X
fnp-3271	59	19	the	the	DET
fnp-3271	59	20	fusion	fusion	NOUN
fnp-3271	59	21	that	that	PRON
fnp-3271	59	22	,	,	PUNCT
fnp-3271	59	23	according	accord	VERB
fnp-3271	59	24	to	to	ADP
fnp-3271	59	25	ryall	ryall	PROPN
fnp-3271	59	26	s	s	PROPN
fnp-3271	59	27	et	et	NOUN
fnp-3271	59	28	al	al	PROPN
fnp-3271	59	29	,	,	PUNCT
fnp-3271	59	30	is	be	AUX
fnp-3271	59	31	the	the	DET
fnp-3271	59	32	primary	primary	ADJ
fnp-3271	59	33	one	one	NOUN
fnp-3271	59	34	seen	see	VERB
fnp-3271	59	35	in	in	ADP
fnp-3271	59	36	plggs	plggs	NOUN
fnp-3271	59	37	with	with	ADP
fnp-3271	59	38	‘	'	PUNCT
fnp-3271	59	39	extensive	extensive	ADJ
fnp-3271	59	40	dissemination	dissemination	NOUN
fnp-3271	59	41	’	'	PUNCT
fnp-3271	59	42	and	and	CCONJ
fnp-3271	59	43	that	that	PRON
fnp-3271	59	44	is	be	AUX
fnp-3271	59	45	associated	associate	VERB
fnp-3271	59	46	with	with	ADP
fnp-3271	59	47	worse	bad	ADJ
fnp-3271	59	48	progression	progression	NOUN
fnp-3271	59	49	-	-	PUNCT
fnp-3271	59	50	free	free	ADJ
fnp-3271	59	51	survival	survival	NOUN
fnp-3271	59	52	.	.	PUNCT
fnp-3271	60	1	topic	topic	NOUN
fnp-3271	60	2	3	3	NUM
fnp-3271	60	3	.	.	PUNCT
fnp-3271	60	4	gene	gene	NOUN
fnp-3271	60	5	fusions	fusion	NOUN
fnp-3271	60	6	in	in	ADP
fnp-3271	60	7	infant	infant	NOUN
fnp-3271	60	8	-	-	PUNCT
fnp-3271	60	9	type	type	NOUN
fnp-3271	60	10	high	high	ADJ
fnp-3271	60	11	-	-	PUNCT
fnp-3271	60	12	grade	grade	NOUN
fnp-3271	60	13	gliomas	glioma	NOUN
fnp-3271	60	14	[	[	X
fnp-3271	60	15	3	3	X
fnp-3271	60	16	]	]	PUNCT
fnp-3271	60	17	in	in	ADP
fnp-3271	60	18	2019	2019	NUM
fnp-3271	60	19	,	,	PUNCT
fnp-3271	60	20	guerreiro	guerreiro	PROPN
fnp-3271	60	21	stucklin	stucklin	PROPN
fnp-3271	60	22	as	as	ADP
fnp-3271	60	23	,	,	PUNCT
fnp-3271	60	24	ryall	ryall	PROPN
fnp-3271	60	25	s	s	PROPN
fnp-3271	60	26	,	,	PUNCT
fnp-3271	60	27	et	et	PROPN
fnp-3271	60	28	al	al	PROPN
fnp-3271	60	29	(	(	PUNCT
fnp-3271	60	30	with	with	ADP
fnp-3271	60	31	tabori	tabori	NOUN
fnp-3271	60	32	u	u	NOUN
fnp-3271	60	33	and	and	CCONJ
fnp-3271	60	34	hawkins	hawkin	NOUN
fnp-3271	60	35	c	c	PROPN
fnp-3271	60	36	as	as	SCONJ
fnp-3271	60	37	last	last	ADJ
fnp-3271	60	38	authors	author	NOUN
fnp-3271	60	39	)	)	PUNCT
fnp-3271	60	40	published	publish	VERB
fnp-3271	60	41	a	a	DET
fnp-3271	60	42	study	study	NOUN
fnp-3271	60	43	of	of	ADP
fnp-3271	60	44	171	171	NUM
fnp-3271	60	45	glioma	glioma	NOUN
fnp-3271	60	46	samples	sample	NOUN
fnp-3271	60	47	from	from	ADP
fnp-3271	60	48	150	150	NUM
fnp-3271	60	49	infants	infant	NOUN
fnp-3271	60	50	in	in	ADP
fnp-3271	60	51	nature	nature	NOUN
fnp-3271	60	52	communications	communication	NOUN
fnp-3271	60	53	in	in	ADP
fnp-3271	60	54	which	which	PRON
fnp-3271	60	55	they	they	PRON
fnp-3271	60	56	identified	identify	VERB
fnp-3271	60	57	three	three	NUM
fnp-3271	60	58	main	main	ADJ
fnp-3271	60	59	subgroups	subgroup	NOUN
fnp-3271	60	60	of	of	ADP
fnp-3271	60	61	infant	infant	NOUN
fnp-3271	60	62	gliomas	glioma	NOUN
fnp-3271	60	63	:	:	PUNCT
fnp-3271	60	64	1	1	X
fnp-3271	60	65	)	)	PUNCT
fnp-3271	60	66	hemispheric	hemispheric	ADJ
fnp-3271	60	67	rtk	rtk	PROPN
fnp-3271	60	68	-	-	PUNCT
fnp-3271	60	69	driven	drive	VERB
fnp-3271	60	70	tumors	tumor	NOUN
fnp-3271	60	71	,	,	PUNCT
fnp-3271	60	72	including	include	VERB
fnp-3271	60	73	those	those	PRON
fnp-3271	60	74	showing	show	VERB
fnp-3271	60	75	fusion	fusion	NOUN
fnp-3271	60	76	involving	involve	VERB
fnp-3271	60	77	alk	alk	PROPN
fnp-3271	60	78	,	,	PUNCT
fnp-3271	60	79	ros1	ros1	PROPN
fnp-3271	60	80	,	,	PUNCT
fnp-3271	60	81	ntrk	ntrk	NOUN
fnp-3271	60	82	,	,	PUNCT
fnp-3271	60	83	or	or	CCONJ
fnp-3271	60	84	met	meet	VERB
fnp-3271	60	85	,	,	PUNCT
fnp-3271	60	86	enriched	enrich	VERB
fnp-3271	60	87	for	for	ADP
fnp-3271	60	88	high	high	ADJ
fnp-3271	60	89	-	-	PUNCT
fnp-3271	60	90	grade	grade	NOUN
fnp-3271	60	91	gliomas	glioma	NOUN
fnp-3271	60	92	and	and	CCONJ
fnp-3271	60	93	with	with	ADP
fnp-3271	60	94	an	an	DET
fnp-3271	60	95	intermediate	intermediate	ADJ
fnp-3271	60	96	clinical	clinical	ADJ
fnp-3271	60	97	outcome	outcome	NOUN
fnp-3271	60	98	;	;	PUNCT
fnp-3271	60	99	2	2	X
fnp-3271	60	100	)	)	PUNCT
fnp-3271	60	101	hemispheric	hemispheric	ADJ
fnp-3271	60	102	ras	ras	PROPN
fnp-3271	60	103	/	/	SYM
fnp-3271	60	104	mapk	mapk	NOUN
fnp-3271	60	105	-	-	PUNCT
fnp-3271	60	106	driven	drive	VERB
fnp-3271	60	107	tumors	tumor	NOUN
fnp-3271	60	108	,	,	PUNCT
fnp-3271	60	109	characterized	characterize	VERB
fnp-3271	60	110	by	by	ADP
fnp-3271	60	111	excellent	excellent	ADJ
fnp-3271	60	112	long	long	ADJ
fnp-3271	60	113	-	-	PUNCT
fnp-3271	60	114	term	term	NOUN
fnp-3271	60	115	survival	survival	NOUN
fnp-3271	60	116	post	post	NOUN
fnp-3271	60	117	-	-	ADJ
fnp-3271	60	118	surgery	surgery	NOUN
fnp-3271	60	119	;	;	PUNCT
fnp-3271	60	120	and	and	CCONJ
fnp-3271	60	121	3	3	X
fnp-3271	60	122	)	)	PUNCT
fnp-3271	60	123	midline	midline	NOUN
fnp-3271	60	124	ras	ras	NOUN
fnp-3271	60	125	/	/	SYM
fnp-3271	60	126	mapk	mapk	NOUN
fnp-3271	60	127	-	-	PUNCT
fnp-3271	60	128	driven	drive	VERB
fnp-3271	60	129	tumors	tumor	NOUN
fnp-3271	60	130	,	,	PUNCT
fnp-3271	60	131	enriched	enrich	VERB
fnp-3271	60	132	for	for	ADP
fnp-3271	60	133	low	low	ADJ
fnp-3271	60	134	-	-	PUNCT
fnp-3271	60	135	grade	grade	NOUN
fnp-3271	60	136	glioma	glioma	NOUN
fnp-3271	60	137	with	with	ADP
fnp-3271	60	138	braf	braf	NOUN
fnp-3271	60	139	alterations	alteration	NOUN
fnp-3271	60	140	and	and	CCONJ
fnp-3271	60	141	a	a	DET
fnp-3271	60	142	relatively	relatively	ADV
fnp-3271	60	143	poor	poor	ADJ
fnp-3271	60	144	outcome	outcome	NOUN
fnp-3271	60	145	,	,	PUNCT
fnp-3271	60	146	even	even	ADV
fnp-3271	60	147	after	after	ADP
fnp-3271	60	148	conventional	conventional	ADJ
fnp-3271	60	149	chemotherapeutic	chemotherapeutic	ADJ
fnp-3271	60	150	approaches	approach	NOUN
fnp-3271	60	151	[	[	X
fnp-3271	60	152	18	18	NUM
fnp-3271	60	153	]	]	PUNCT
fnp-3271	60	154	.	.	PUNCT
fnp-3271	61	1	in	in	ADP
fnp-3271	61	2	2020	2020	NUM
fnp-3271	61	3	,	,	PUNCT
fnp-3271	61	4	clarke	clarke	PROPN
fnp-3271	61	5	m	m	PROPN
fnp-3271	61	6	,	,	PUNCT
fnp-3271	61	7	mackay	mackay	PROPN
fnp-3271	61	8	a	a	PROPN
fnp-3271	61	9	,	,	PUNCT
fnp-3271	61	10	ismer	ismer	NOUN
fnp-3271	61	11	b	b	PROPN
fnp-3271	61	12	,	,	PUNCT
fnp-3271	61	13	et	et	PROPN
fnp-3271	61	14	al	al	PROPN
fnp-3271	61	15	(	(	PUNCT
fnp-3271	61	16	last	last	ADJ
fnp-3271	61	17	author	author	NOUN
fnp-3271	61	18	jones	jones	PROPN
fnp-3271	61	19	c	c	PROPN
fnp-3271	61	20	)	)	PUNCT
fnp-3271	61	21	published	publish	VERB
fnp-3271	61	22	in	in	ADP
fnp-3271	61	23	cancer	cancer	NOUN
fnp-3271	61	24	discovery	discovery	NOUN
fnp-3271	61	25	the	the	DET
fnp-3271	61	26	findings	finding	NOUN
fnp-3271	61	27	of	of	ADP
fnp-3271	61	28	a	a	DET
fnp-3271	61	29	thorough	thorough	ADJ
fnp-3271	61	30	histological	histological	ADJ
fnp-3271	61	31	and	and	CCONJ
fnp-3271	61	32	molecular	molecular	ADJ
fnp-3271	61	33	analysis	analysis	NOUN
fnp-3271	61	34	of	of	ADP
fnp-3271	61	35	241	241	NUM
fnp-3271	61	36	tumors	tumor	NOUN
fnp-3271	61	37	diagnosed	diagnose	VERB
fnp-3271	61	38	as	as	ADP
fnp-3271	61	39	high	high	ADJ
fnp-3271	61	40	-	-	PUNCT
fnp-3271	61	41	grade	grade	NOUN
fnp-3271	61	42	and/or	and/or	CCONJ
fnp-3271	61	43	diffuse	diffuse	VERB
fnp-3271	61	44	gliomas	glioma	NOUN
fnp-3271	61	45	in	in	ADP
fnp-3271	61	46	children	child	NOUN
fnp-3271	61	47	<	<	X
fnp-3271	61	48	4	4	NUM
fnp-3271	61	49	years	year	NOUN
fnp-3271	61	50	of	of	ADP
fnp-3271	61	51	age	age	NOUN
fnp-3271	61	52	at	at	ADP
fnp-3271	61	53	the	the	DET
fnp-3271	61	54	time	time	NOUN
fnp-3271	61	55	of	of	ADP
fnp-3271	61	56	diagnosis	diagnosis	NOUN
fnp-3271	61	57	[	[	X
fnp-3271	61	58	3	3	NUM
fnp-3271	61	59	]	]	PUNCT
fnp-3271	61	60	.	.	PUNCT
fnp-3271	62	1	after	after	ADP
fnp-3271	62	2	excluding	exclude	VERB
fnp-3271	62	3	non	non	ADJ
fnp-3271	62	4	-	-	ADJ
fnp-3271	62	5	gliomas	glioma	NOUN
fnp-3271	62	6	and	and	CCONJ
fnp-3271	62	7	gliomas	glioma	NOUN
fnp-3271	62	8	matching	match	VERB
fnp-3271	62	9	known	know	VERB
fnp-3271	62	10	subtypes	subtype	NOUN
fnp-3271	62	11	,	,	PUNCT
fnp-3271	62	12	130	130	NUM
fnp-3271	62	13	infant	infant	NOUN
fnp-3271	62	14	gliomas	glioma	NOUN
fnp-3271	62	15	remained	remain	VERB
fnp-3271	62	16	that	that	PRON
fnp-3271	62	17	seemed	seem	VERB
fnp-3271	62	18	to	to	PART
fnp-3271	62	19	be	be	AUX
fnp-3271	62	20	part	part	NOUN
fnp-3271	62	21	of	of	ADP
fnp-3271	62	22	an	an	DET
fnp-3271	62	23	"	"	PUNCT
fnp-3271	62	24	intrinsic	intrinsic	ADJ
fnp-3271	62	25	"	"	PUNCT
fnp-3271	62	26	spectrum	spectrum	NOUN
fnp-3271	62	27	of	of	ADP
fnp-3271	62	28	disease	disease	NOUN
fnp-3271	62	29	specific	specific	ADJ
fnp-3271	62	30	to	to	ADP
fnp-3271	62	31	the	the	DET
fnp-3271	62	32	infant	infant	NOUN
fnp-3271	62	33	population	population	NOUN
fnp-3271	62	34	.	.	PUNCT
fnp-3271	63	1	these	these	PRON
fnp-3271	63	2	included	include	VERB
fnp-3271	63	3	those	those	PRON
fnp-3271	63	4	with	with	ADP
fnp-3271	63	5	targetable	targetable	ADJ
fnp-3271	63	6	mapk	mapk	NOUN
fnp-3271	63	7	pathway	pathway	NOUN
fnp-3271	63	8	alterations	alteration	NOUN
fnp-3271	63	9	.	.	PUNCT
fnp-3271	64	1	a	a	DET
fnp-3271	64	2	large	large	ADJ
fnp-3271	64	3	proportion	proportion	NOUN
fnp-3271	64	4	of	of	ADP
fnp-3271	64	5	remaining	remain	VERB
fnp-3271	64	6	cases	case	NOUN
fnp-3271	64	7	harbored	harbor	VERB
fnp-3271	64	8	gene	gene	NOUN
fnp-3271	64	9	fusions	fusion	NOUN
fnp-3271	64	10	;	;	PUNCT
fnp-3271	64	11	these	these	DET
fnp-3271	64	12	tumors	tumor	NOUN
fnp-3271	64	13	typically	typically	ADV
fnp-3271	64	14	occurred	occur	VERB
fnp-3271	64	15	in	in	ADP
fnp-3271	64	16	very	very	ADV
fnp-3271	64	17	young	young	ADJ
fnp-3271	64	18	children	child	NOUN
fnp-3271	64	19	(	(	PUNCT
fnp-3271	64	20	age	age	NOUN
fnp-3271	64	21	at	at	ADP
fnp-3271	64	22	diagnosis	diagnosis	NOUN
fnp-3271	64	23	less	less	ADJ
fnp-3271	64	24	than	than	ADP
fnp-3271	64	25	<	<	X
fnp-3271	64	26	1	1	NUM
fnp-3271	64	27	year	year	NOUN
fnp-3271	64	28	)	)	PUNCT
fnp-3271	64	29	,	,	PUNCT
fnp-3271	64	30	were	be	AUX
fnp-3271	64	31	located	locate	VERB
fnp-3271	64	32	in	in	ADP
fnp-3271	64	33	the	the	DET
fnp-3271	64	34	cerebral	cerebral	ADJ
fnp-3271	64	35	hemispheres	hemisphere	NOUN
fnp-3271	64	36	,	,	PUNCT
fnp-3271	64	37	and	and	CCONJ
fnp-3271	64	38	(	(	PUNCT
fnp-3271	64	39	like	like	ADP
fnp-3271	64	40	the	the	DET
fnp-3271	64	41	‘	'	PUNCT
fnp-3271	64	42	group	group	NOUN
fnp-3271	64	43	1	1	NUM
fnp-3271	64	44	tumors	tumor	NOUN
fnp-3271	64	45	’	'	PUNCT
fnp-3271	64	46	as	as	SCONJ
fnp-3271	64	47	reported	report	VERB
fnp-3271	64	48	by	by	ADP
fnp-3271	64	49	guerreiro	guerreiro	PROPN
fnp-3271	64	50	stucklin	stucklin	PROPN
fnp-3271	64	51	as	as	ADP
fnp-3271	64	52	et	et	PROPN
fnp-3271	64	53	al	al	PROPN
fnp-3271	64	54	)	)	PUNCT
fnp-3271	64	55	frequently	frequently	ADV
fnp-3271	64	56	carried	carry	VERB
fnp-3271	64	57	fusions	fusion	NOUN
fnp-3271	64	58	involving	involve	VERB
fnp-3271	64	59	alk	alk	NOUN
fnp-3271	64	60	(	(	PUNCT
fnp-3271	64	61	n	n	NOUN
fnp-3271	64	62	=	=	SYM
fnp-3271	64	63	31	31	NUM
fnp-3271	64	64	)	)	PUNCT
fnp-3271	64	65	,	,	PUNCT
fnp-3271	64	66	ntrk1	ntrk1	NOUN
fnp-3271	64	67	/	/	SYM
fnp-3271	64	68	ntrk2	ntrk2	PROPN
fnp-3271	64	69	/	/	SYM
fnp-3271	64	70	ntrk3	ntrk3	PROPN
fnp-3271	64	71	(	(	PUNCT
fnp-3271	64	72	n	n	NOUN
fnp-3271	64	73	=	=	NUM
fnp-3271	64	74	21	21	NUM
fnp-3271	64	75	)	)	PUNCT
fnp-3271	64	76	,	,	PUNCT
fnp-3271	65	1	ros1	ros1	PROPN
fnp-3271	65	2	(	(	PUNCT
fnp-3271	65	3	n	n	NOUN
fnp-3271	65	4	=	=	NOUN
fnp-3271	65	5	9	9	NUM
fnp-3271	65	6	)	)	PUNCT
fnp-3271	65	7	,	,	PUNCT
fnp-3271	65	8	or	or	CCONJ
fnp-3271	65	9	met	meet	VERB
fnp-3271	65	10	(	(	PUNCT
fnp-3271	65	11	n	n	NOUN
fnp-3271	65	12	=	=	SYM
fnp-3271	65	13	4	4	NUM
fnp-3271	65	14	)	)	PUNCT
fnp-3271	65	15	as	as	ADP
fnp-3271	65	16	their	their	PRON
fnp-3271	65	17	driving	driving	NOUN
fnp-3271	65	18	alterations	alteration	NOUN
fnp-3271	65	19	.	.	PUNCT
fnp-3271	66	1	importantly	importantly	ADV
fnp-3271	66	2	,	,	PUNCT
fnp-3271	66	3	compared	compare	VERB
fnp-3271	66	4	to	to	ADP
fnp-3271	66	5	the	the	DET
fnp-3271	66	6	fusion	fusion	NOUN
fnp-3271	66	7	-	-	PUNCT
fnp-3271	66	8	negative	negative	ADJ
fnp-3271	66	9	tumors	tumor	NOUN
fnp-3271	66	10	in	in	ADP
fnp-3271	66	11	this	this	DET
fnp-3271	66	12	group	group	NOUN
fnp-3271	66	13	,	,	PUNCT
fnp-3271	66	14	these	these	DET
fnp-3271	66	15	fusion	fusion	NOUN
fnp-3271	66	16	-	-	PUNCT
fnp-3271	66	17	positive	positive	ADJ
fnp-3271	66	18	tumors	tumor	NOUN
fnp-3271	66	19	had	have	VERB
fnp-3271	66	20	significantly	significantly	ADV
fnp-3271	66	21	better	well	ADJ
fnp-3271	66	22	outcomes	outcome	NOUN
fnp-3271	66	23	.	.	PUNCT
fnp-3271	67	1	also	also	ADV
fnp-3271	67	2	,	,	PUNCT
fnp-3271	67	3	they	they	PRON
fnp-3271	67	4	would	would	AUX
fnp-3271	67	5	be	be	AUX
fnp-3271	67	6	good	good	ADJ
fnp-3271	67	7	candidates	candidate	NOUN
fnp-3271	67	8	for	for	ADP
fnp-3271	67	9	targeted	target	VERB
fnp-3271	67	10	therapy	therapy	NOUN
fnp-3271	67	11	.	.	PUNCT
fnp-3271	68	1	this	this	DET
fnp-3271	68	2	study	study	NOUN
fnp-3271	68	3	is	be	AUX
fnp-3271	68	4	a	a	DET
fnp-3271	68	5	next	next	ADJ
fnp-3271	68	6	example	example	NOUN
fnp-3271	68	7	of	of	ADP
fnp-3271	68	8	how	how	SCONJ
fnp-3271	68	9	in	in	ADP
fnp-3271	68	10	-	-	PUNCT
fnp-3271	68	11	depth	depth	NOUN
fnp-3271	68	12	molecular	molecular	ADJ
fnp-3271	68	13	profiling	profiling	NOUN
fnp-3271	68	14	of	of	ADP
fnp-3271	68	15	pediatric	pediatric	ADJ
fnp-3271	68	16	brain	brain	NOUN
fnp-3271	68	17	tumors	tumor	NOUN
fnp-3271	68	18	not	not	PART
fnp-3271	68	19	only	only	ADV
fnp-3271	68	20	greatly	greatly	ADV
fnp-3271	68	21	helps	help	VERB
fnp-3271	68	22	to	to	PART
fnp-3271	68	23	improve	improve	VERB
fnp-3271	68	24	prognostication	prognostication	NOUN
fnp-3271	68	25	for	for	ADP
fnp-3271	68	26	the	the	DET
fnp-3271	68	27	children	child	NOUN
fnp-3271	68	28	suffering	suffer	VERB
fnp-3271	68	29	from	from	ADP
fnp-3271	68	30	these	these	DET
fnp-3271	68	31	neoplasms	neoplasm	NOUN
fnp-3271	68	32	,	,	PUNCT
fnp-3271	68	33	but	but	CCONJ
fnp-3271	68	34	also	also	ADV
fnp-3271	68	35	to	to	PART
fnp-3271	68	36	discover	discover	VERB
fnp-3271	68	37	actionable	actionable	ADJ
fnp-3271	68	38	targets	target	NOUN
fnp-3271	68	39	that	that	PRON
fnp-3271	68	40	have	have	VERB
fnp-3271	68	41	the	the	DET
fnp-3271	68	42	potential	potential	NOUN
fnp-3271	68	43	to	to	PART
fnp-3271	68	44	substantially	substantially	ADV
fnp-3271	68	45	improve	improve	VERB
fnp-3271	68	46	their	their	PRON
fnp-3271	68	47	prognosis	prognosis	NOUN
fnp-3271	68	48	[	[	X
fnp-3271	68	49	19	19	NUM
fnp-3271	68	50	]	]	PUNCT
fnp-3271	68	51	.	.	PUNCT
fnp-3271	69	1	topic	topic	NOUN
fnp-3271	69	2	4	4	NUM
fnp-3271	69	3	.	.	X
fnp-3271	69	4	hypermutation	hypermutation	NOUN
fnp-3271	69	5	in	in	ADP
fnp-3271	69	6	gliomas	glioma	NOUN
fnp-3271	70	1	[	[	X
fnp-3271	70	2	4	4	NUM
fnp-3271	70	3	]	]	PUNCT
fnp-3271	70	4	while	while	SCONJ
fnp-3271	70	5	only	only	ADV
fnp-3271	70	6	a	a	DET
fnp-3271	70	7	limited	limited	ADJ
fnp-3271	70	8	number	number	NOUN
fnp-3271	70	9	of	of	ADP
fnp-3271	70	10	newly	newly	ADV
fnp-3271	70	11	diagnosed	diagnose	VERB
fnp-3271	70	12	gliomas	glioma	NOUN
fnp-3271	70	13	are	be	AUX
fnp-3271	70	14	characterized	characterize	VERB
fnp-3271	70	15	by	by	ADP
fnp-3271	70	16	an	an	DET
fnp-3271	70	17	inherited	inherit	VERB
fnp-3271	70	18	mismatch	mismatch	NOUN
fnp-3271	70	19	repair	repair	NOUN
fnp-3271	70	20	(	(	PUNCT
fnp-3271	70	21	mmr	mmr	PROPN
fnp-3271	70	22	)	)	PUNCT
fnp-3271	70	23	defect	defect	NOUN
fnp-3271	70	24	and/or	and/or	CCONJ
fnp-3271	70	25	a	a	DET
fnp-3271	70	26	‘	'	PUNCT
fnp-3271	70	27	hypermutator	hypermutator	NOUN
fnp-3271	70	28	’	'	PUNCT
fnp-3271	70	29	phenotype	phenotype	NOUN
fnp-3271	70	30	,	,	PUNCT
fnp-3271	70	31	recurrent	recurrent	ADJ
fnp-3271	70	32	gliomas	glioma	NOUN
fnp-3271	70	33	more	more	ADV
fnp-3271	70	34	often	often	ADV
fnp-3271	70	35	show	show	VERB
fnp-3271	70	36	such	such	DET
fnp-3271	70	37	a	a	DET
fnp-3271	70	38	phenotype	phenotype	NOUN
fnp-3271	70	39	,	,	PUNCT
fnp-3271	70	40	especially	especially	ADV
fnp-3271	70	41	after	after	ADP
fnp-3271	70	42	alkylating	alkylate	VERB
fnp-3271	70	43	chemotherapy	chemotherapy	NOUN
fnp-3271	70	44	[	[	X
fnp-3271	70	45	20	20	NUM
fnp-3271	70	46	]	]	PUNCT
fnp-3271	70	47	.	.	PUNCT
fnp-3271	71	1	the	the	DET
fnp-3271	71	2	combination	combination	NOUN
fnp-3271	71	3	of	of	ADP
fnp-3271	71	4	low	low	ADJ
fnp-3271	71	5	tumor	tumor	NOUN
fnp-3271	71	6	mutational	mutational	ADJ
fnp-3271	71	7	burden	burden	NOUN
fnp-3271	71	8	(	(	PUNCT
fnp-3271	71	9	tmb	tmb	NOUN
fnp-3271	71	10	)	)	PUNCT
fnp-3271	71	11	and	and	CCONJ
fnp-3271	71	12	a	a	DET
fnp-3271	71	13	highly	highly	ADV
fnp-3271	71	14	immunosuppressive	immunosuppressive	ADJ
fnp-3271	71	15	microenvironment	microenvironment	NOUN
fnp-3271	71	16	in	in	ADP
fnp-3271	71	17	most	most	ADV
fnp-3271	71	18	newly	newly	ADV
fnp-3271	71	19	diagnosed	diagnose	VERB
fnp-3271	71	20	diffuse	diffuse	NOUN
fnp-3271	71	21	gliomas	glioma	NOUN
fnp-3271	71	22	renders	render	VERB
fnp-3271	71	23	(	(	PUNCT
fnp-3271	71	24	at	at	ADP
fnp-3271	71	25	least	least	ADJ
fnp-3271	71	26	so	so	ADV
fnp-3271	71	27	far	far	ADV
fnp-3271	71	28	)	)	PUNCT
fnp-3271	71	29	effective	effective	ADJ
fnp-3271	71	30	immunotherapy	immunotherapy	NOUN
fnp-3271	71	31	for	for	ADP
fnp-3271	71	32	these	these	DET
fnp-3271	71	33	tumors	tumor	NOUN
fnp-3271	71	34	quite	quite	ADV
fnp-3271	71	35	challenging	challenging	ADJ
fnp-3271	71	36	.	.	PUNCT
fnp-3271	72	1	assuming	assume	VERB
fnp-3271	72	2	that	that	SCONJ
fnp-3271	72	3	the	the	DET
fnp-3271	72	4	hypermutator	hypermutator	NOUN
fnp-3271	72	5	status	status	NOUN
fnp-3271	72	6	leads	lead	VERB
fnp-3271	72	7	to	to	ADP
fnp-3271	72	8	an	an	DET
fnp-3271	72	9	increased	increase	VERB
fnp-3271	72	10	expression	expression	NOUN
fnp-3271	72	11	of	of	ADP
fnp-3271	72	12	neoantigens	neoantigen	NOUN
fnp-3271	72	13	,	,	PUNCT
fnp-3271	72	14	gliomas	glioma	NOUN
fnp-3271	72	15	/	/	SYM
fnp-3271	72	16	glioblastomas	glioblastoma	NOUN
fnp-3271	72	17	with	with	ADP
fnp-3271	72	18	a	a	DET
fnp-3271	72	19	hypermutator	hypermutator	NOUN
fnp-3271	72	20	phenotype	phenotype	NOUN
fnp-3271	72	21	could	could	AUX
fnp-3271	72	22	be	be	AUX
fnp-3271	72	23	better	well	ADJ
fnp-3271	72	24	candidates	candidate	NOUN
fnp-3271	72	25	for	for	ADP
fnp-3271	72	26	immune	immune	ADJ
fnp-3271	72	27	checkpoint	checkpoint	NOUN
fnp-3271	72	28	blockade	blockade	NOUN
fnp-3271	72	29	.	.	PUNCT
fnp-3271	73	1	in	in	ADP
fnp-3271	73	2	a	a	DET
fnp-3271	73	3	paper	paper	NOUN
fnp-3271	73	4	in	in	ADP
fnp-3271	73	5	nature	nature	NOUN
fnp-3271	73	6	,	,	PUNCT
fnp-3271	73	7	touat	touat	PROPN
fnp-3271	73	8	m	m	PROPN
fnp-3271	73	9	and	and	CCONJ
fnp-3271	73	10	li	li	PROPN
fnp-3271	73	11	yy	yy	PROPN
fnp-3271	73	12	,	,	PUNCT
fnp-3271	73	13	et	et	PROPN
fnp-3271	73	14	al	al	PROPN
fnp-3271	73	15	(	(	PUNCT
fnp-3271	73	16	with	with	ADP
fnp-3271	73	17	beroukhim	beroukhim	PROPN
fnp-3271	73	18	r	r	NOUN
fnp-3271	73	19	,	,	PUNCT
fnp-3271	73	20	bandopadhayay	bandopadhayay	NOUN
fnp-3271	73	21	p	p	NOUN
fnp-3271	73	22	,	,	PUNCT
fnp-3271	73	23	bielle	bielle	NOUN
fnp-3271	73	24	f	f	X
fnp-3271	73	25	,	,	PUNCT
fnp-3271	73	26	and	and	CCONJ
fnp-3271	73	27	ligon	ligon	PROPN
fnp-3271	73	28	kl	kl	PROPN
fnp-3271	73	29	as	as	ADP
fnp-3271	73	30	supervising	supervise	VERB
fnp-3271	73	31	authors	author	NOUN
fnp-3271	73	32	)	)	PUNCT
fnp-3271	73	33	report	report	VERB
fnp-3271	73	34	the	the	DET
fnp-3271	73	35	results	result	NOUN
fnp-3271	73	36	of	of	ADP
fnp-3271	73	37	their	their	PRON
fnp-3271	73	38	comprehensive	comprehensive	ADJ
fnp-3271	73	39	analysis	analysis	NOUN
fnp-3271	73	40	of	of	ADP
fnp-3271	73	41	the	the	DET
fnp-3271	73	42	molecular	molecular	ADJ
fnp-3271	73	43	determinants	determinant	NOUN
fnp-3271	73	44	of	of	ADP
fnp-3271	73	45	mutational	mutational	ADJ
fnp-3271	73	46	burden	burden	NOUN
fnp-3271	73	47	and	and	CCONJ
fnp-3271	73	48	signatures	signature	NOUN
fnp-3271	73	49	in	in	ADP
fnp-3271	73	50	10,294	10,294	NUM
fnp-3271	73	51	gliomas	glioma	NOUN
fnp-3271	73	52	[	[	X
fnp-3271	73	53	4	4	NUM
fnp-3271	73	54	]	]	PUNCT
fnp-3271	73	55	.	.	PUNCT
fnp-3271	74	1	the	the	DET
fnp-3271	74	2	gliomas	glioma	NOUN
fnp-3271	74	3	were	be	AUX
fnp-3271	74	4	classified	classify	VERB
fnp-3271	74	5	into	into	ADP
fnp-3271	74	6	molecular	molecular	ADJ
fnp-3271	74	7	subgroups	subgroup	NOUN
fnp-3271	74	8	according	accord	VERB
fnp-3271	74	9	to	to	ADP
fnp-3271	74	10	histopathology	histopathology	NOUN
fnp-3271	74	11	as	as	ADV
fnp-3271	74	12	well	well	ADV
fnp-3271	74	13	as	as	ADP
fnp-3271	74	14	idh1	idh1	PROPN
fnp-3271	74	15	/	/	SYM
fnp-3271	74	16	idh2	idh2	PROPN
fnp-3271	75	1	and	and	CCONJ
fnp-3271	75	2	1p/19q	1p/19q	PROPN
fnp-3271	75	3	codeletion	codeletion	PROPN
fnp-3271	75	4	status	status	NOUN
fnp-3271	75	5	.	.	PUNCT
fnp-3271	76	1	the	the	DET
fnp-3271	76	2	median	median	PROPN
fnp-3271	76	3	tmb	tmb	PROPN
fnp-3271	76	4	in	in	ADP
fnp-3271	76	5	all	all	DET
fnp-3271	76	6	samples	sample	NOUN
fnp-3271	76	7	was	be	AUX
fnp-3271	76	8	2.6	2.6	NUM
fnp-3271	76	9	mutations	mutation	NOUN
fnp-3271	76	10	per	per	ADP
fnp-3271	76	11	mb	mb	X
fnp-3271	76	12	(	(	PUNCT
fnp-3271	76	13	range	range	PROPN
fnp-3271	76	14	0.0–781.3	0.0–781.3	PROPN
fnp-3271	76	15	)	)	PUNCT
fnp-3271	76	16	.	.	PUNCT
fnp-3271	77	1	558	558	NUM
fnp-3271	77	2	(	(	PUNCT
fnp-3271	77	3	5.4	5.4	NUM
fnp-3271	77	4	%	%	NOUN
fnp-3271	77	5	)	)	PUNCT
fnp-3271	77	6	tumors	tumor	NOUN
fnp-3271	77	7	that	that	PRON
fnp-3271	77	8	were	be	AUX
fnp-3271	77	9	designated	designate	VERB
fnp-3271	77	10	as	as	ADP
fnp-3271	77	11	being	be	AUX
fnp-3271	77	12	hypermutated	hypermutate	VERB
fnp-3271	77	13	(	(	PUNCT
fnp-3271	77	14	median	median	PROPN
fnp-3271	77	15	tmb	tmb	PROPN
fnp-3271	77	16	50.8	50.8	NUM
fnp-3271	77	17	mutations	mutation	NOUN
fnp-3271	77	18	per	per	ADP
fnp-3271	77	19	mb	mb	NOUN
fnp-3271	77	20	,	,	PUNCT
fnp-3271	77	21	range	range	NOUN
fnp-3271	77	22	8.8–781.3	8.8–781.3	NUM
fnp-3271	77	23	)	)	PUNCT
fnp-3271	77	24	were	be	AUX
fnp-3271	77	25	analyzed	analyze	VERB
fnp-3271	77	26	more	more	ADV
fnp-3271	77	27	in	in	ADP
fnp-3271	77	28	depth	depth	NOUN
fnp-3271	77	29	.	.	PUNCT
fnp-3271	78	1	the	the	DET
fnp-3271	78	2	majority	majority	NOUN
fnp-3271	78	3	of	of	ADP
fnp-3271	78	4	de	de	X
fnp-3271	78	5	novo	novo	PROPN
fnp-3271	78	6	hypermutated	hypermutate	VERB
fnp-3271	78	7	gliomas	glioma	NOUN
fnp-3271	78	8	harbored	harbor	VERB
fnp-3271	78	9	mutational	mutational	ADJ
fnp-3271	78	10	signatures	signature	NOUN
fnp-3271	78	11	associated	associate	VERB
fnp-3271	78	12	with	with	ADP
fnp-3271	78	13	defects	defect	NOUN
fnp-3271	78	14	in	in	ADP
fnp-3271	78	15	the	the	DET
fnp-3271	78	16	mmr	mmr	PROPN
fnp-3271	78	17	pathway	pathway	NOUN
fnp-3271	78	18	(	(	PUNCT
fnp-3271	78	19	cosmic	cosmic	ADJ
fnp-3271	78	20	signatures	signature	NOUN
fnp-3271	78	21	6	6	NUM
fnp-3271	78	22	,	,	PUNCT
fnp-3271	78	23	15	15	NUM
fnp-3271	78	24	,	,	PUNCT
fnp-3271	78	25	26	26	NUM
fnp-3271	78	26	and	and	CCONJ
fnp-3271	78	27	14	14	NUM
fnp-3271	78	28	)	)	PUNCT
fnp-3271	78	29	or	or	CCONJ
fnp-3271	78	30	the	the	DET
fnp-3271	78	31	dna	dna	PROPN
fnp-3271	78	32	polymerase	polymerase	NOUN
fnp-3271	78	33	pole	pole	NOUN
fnp-3271	78	34	(	(	PUNCT
fnp-3271	78	35	10	10	NUM
fnp-3271	78	36	and	and	CCONJ
fnp-3271	78	37	14	14	NUM
fnp-3271	78	38	)	)	PUNCT
fnp-3271	78	39	(	(	PUNCT
fnp-3271	78	40	2/3	2/3	NUM
fnp-3271	78	41	and	and	CCONJ
fnp-3271	78	42	1/3	1/3	NUM
fnp-3271	78	43	of	of	ADP
fnp-3271	78	44	the	the	DET
fnp-3271	78	45	samples	sample	NOUN
fnp-3271	78	46	,	,	PUNCT
fnp-3271	78	47	respectively	respectively	ADV
fnp-3271	78	48	)	)	PUNCT
fnp-3271	78	49	,	,	PUNCT
fnp-3271	78	50	implying	imply	VERB
fnp-3271	78	51	that	that	SCONJ
fnp-3271	78	52	constitutional	constitutional	ADJ
fnp-3271	78	53	deficiency	deficiency	NOUN
fnp-3271	78	54	in	in	ADP
fnp-3271	78	55	mmr	mmr	PROPN
fnp-3271	78	56	or	or	CCONJ
fnp-3271	78	57	pole	pole	NOUN
fnp-3271	78	58	was	be	AUX
fnp-3271	78	59	likely	likely	ADJ
fnp-3271	78	60	to	to	PART
fnp-3271	78	61	be	be	AUX
fnp-3271	78	62	the	the	DET
fnp-3271	78	63	underlying	underlying	ADJ
fnp-3271	78	64	genetic	genetic	ADJ
fnp-3271	78	65	cause	cause	NOUN
fnp-3271	78	66	of	of	ADP
fnp-3271	78	67	hypermutation	hypermutation	NOUN
fnp-3271	78	68	.	.	PUNCT
fnp-3271	79	1	in	in	ADP
fnp-3271	79	2	contrast	contrast	NOUN
fnp-3271	79	3	,	,	PUNCT
fnp-3271	79	4	almost	almost	ADV
fnp-3271	79	5	all	all	PRON
fnp-3271	79	6	gliomas	glioma	NOUN
fnp-3271	79	7	showing	show	VERB
fnp-3271	79	8	high	high	ADJ
fnp-3271	79	9	tmb	tmb	NUM
fnp-3271	79	10	post	post	NOUN
fnp-3271	79	11	-	-	NOUN
fnp-3271	79	12	treatment	treatment	NOUN
fnp-3271	79	13	had	have	VERB
fnp-3271	79	14	a	a	DET
fnp-3271	79	15	mutational	mutational	ADJ
fnp-3271	79	16	signature	signature	NOUN
fnp-3271	79	17	associated	associate	VERB
fnp-3271	79	18	with	with	ADP
fnp-3271	79	19	temozolomide	temozolomide	NOUN
fnp-3271	79	20	exposure	exposure	NOUN
fnp-3271	79	21	(	(	PUNCT
fnp-3271	79	22	signature	signature	NOUN
fnp-3271	79	23	11	11	NUM
fnp-3271	79	24	)	)	PUNCT
fnp-3271	79	25	,	,	PUNCT
fnp-3271	79	26	and	and	CCONJ
fnp-3271	79	27	half	half	NOUN
fnp-3271	79	28	of	of	ADP
fnp-3271	79	29	these	these	DET
fnp-3271	79	30	samples	sample	NOUN
fnp-3271	79	31	showed	show	VERB
fnp-3271	79	32	a	a	DET
fnp-3271	79	33	co	co	ADJ
fnp-3271	79	34	-	-	ADJ
fnp-3271	79	35	existing	existing	ADJ
fnp-3271	79	36	minor	minor	ADJ
fnp-3271	79	37	mmror	mmror	NOUN
fnp-3271	79	38	pole	pole	ADJ
fnp-3271	79	39	-	-	PUNCT
fnp-3271	79	40	deficiency	deficiency	NOUN
fnp-3271	79	41	signature	signature	NOUN
fnp-3271	79	42	component	component	NOUN
fnp-3271	79	43	,	,	PUNCT
fnp-3271	79	44	suggesting	suggest	VERB
fnp-3271	79	45	that	that	SCONJ
fnp-3271	79	46	defective	defective	ADJ
fnp-3271	79	47	dna	dna	PROPN
fnp-3271	79	48	repair	repair	NOUN
fnp-3271	79	49	and	and	CCONJ
fnp-3271	79	50	mutagen	mutagen	NOUN
fnp-3271	79	51	exposure	exposure	NOUN
fnp-3271	79	52	cooperate	cooperate	VERB
fnp-3271	79	53	to	to	PART
fnp-3271	79	54	drive	drive	VERB
fnp-3271	79	55	hypermutation	hypermutation	NOUN
fnp-3271	79	56	in	in	ADP
fnp-3271	79	57	these	these	DET
fnp-3271	79	58	recurrent	recurrent	ADJ
fnp-3271	79	59	gliomas	glioma	NOUN
fnp-3271	79	60	.	.	PUNCT
fnp-3271	80	1	the	the	DET
fnp-3271	80	2	observation	observation	NOUN
fnp-3271	80	3	that	that	SCONJ
fnp-3271	80	4	bulk	bulk	ADJ
fnp-3271	80	5	analyses	analysis	NOUN
fnp-3271	80	6	of	of	ADP
fnp-3271	80	7	such	such	ADJ
fnp-3271	80	8	post	post	ADJ
fnp-3271	80	9	-	-	ADJ
fnp-3271	80	10	treatment	treatment	ADJ
fnp-3271	80	11	hypermutated	hypermutate	VERB
fnp-3271	80	12	glioma	glioma	NOUN
fnp-3271	80	13	did	do	AUX
fnp-3271	80	14	not	not	PART
fnp-3271	80	15	readily	readily	ADV
fnp-3271	80	16	detect	detect	VERB
fnp-3271	80	17	microsatellite	microsatellite	ADJ
fnp-3271	80	18	instabilities	instability	NOUN
fnp-3271	80	19	(	(	PUNCT
fnp-3271	80	20	msis	msis	NOUN
fnp-3271	80	21	)	)	PUNCT
fnp-3271	80	22	,	,	PUNCT
fnp-3271	80	23	while	while	SCONJ
fnp-3271	80	24	single	single	ADJ
fnp-3271	80	25	-	-	PUNCT
fnp-3271	80	26	cell	cell	NOUN
fnp-3271	80	27	whole	whole	ADJ
fnp-3271	80	28	-	-	PUNCT
fnp-3271	80	29	genome	genome	NOUN
fnp-3271	80	30	sequencing	sequencing	NOUN
fnp-3271	80	31	analysis	analysis	NOUN
fnp-3271	80	32	did	do	AUX
fnp-3271	80	33	identify	identify	VERB
fnp-3271	80	34	microsatellite	microsatellite	ADJ
fnp-3271	80	35	mutations	mutation	NOUN
fnp-3271	80	36	,	,	PUNCT
fnp-3271	80	37	can	can	AUX
fnp-3271	80	38	be	be	AUX
fnp-3271	80	39	explained	explain	VERB
fnp-3271	80	40	by	by	ADP
fnp-3271	80	41	intra	intra	ADJ
fnp-3271	80	42	-	-	ADJ
fnp-3271	80	43	tumor	tumor	ADJ
fnp-3271	80	44	heterogeneity	heterogeneity	NOUN
fnp-3271	80	45	for	for	ADP
fnp-3271	80	46	this	this	DET
fnp-3271	80	47	characteristic	characteristic	NOUN
fnp-3271	80	48	and	and	CCONJ
fnp-3271	80	49	a	a	DET
fnp-3271	80	50	lack	lack	NOUN
fnp-3271	80	51	of	of	ADP
fnp-3271	80	52	sufficient	sufficient	ADJ
fnp-3271	80	53	evolutionary	evolutionary	ADJ
fnp-3271	80	54	time	time	NOUN
fnp-3271	80	55	to	to	PART
fnp-3271	80	56	select	select	VERB
fnp-3271	80	57	subclonal	subclonal	ADJ
fnp-3271	80	58	msi	msi	PROPN
fnp-3271	80	59	populations	population	NOUN
fnp-3271	80	60	.	.	PUNCT
fnp-3271	81	1	while	while	SCONJ
fnp-3271	81	2	the	the	DET
fnp-3271	81	3	therapy	therapy	NOUN
fnp-3271	81	4	-	-	PUNCT
fnp-3271	81	5	induced	induce	VERB
fnp-3271	81	6	snv	snv	NOUN
fnp-3271	81	7	mutations	mutation	NOUN
fnp-3271	81	8	might	might	AUX
fnp-3271	81	9	not	not	PART
fnp-3271	81	10	readily	readily	ADV
fnp-3271	81	11	elicit	elicit	VERB
fnp-3271	81	12	effective	effective	ADJ
fnp-3271	81	13	antitumor	antitumor	NOUN
fnp-3271	81	14	responses	response	NOUN
fnp-3271	81	15	(	(	PUNCT
fnp-3271	81	16	because	because	SCONJ
fnp-3271	81	17	of	of	ADP
fnp-3271	81	18	,	,	PUNCT
fnp-3271	81	19	for	for	ADP
fnp-3271	81	20	example	example	NOUN
fnp-3271	81	21	,	,	PUNCT
fnp-3271	81	22	the	the	DET
fnp-3271	81	23	quality	quality	NOUN
fnp-3271	81	24	of	of	ADP
fnp-3271	81	25	the	the	DET
fnp-3271	81	26	mutations	mutation	NOUN
fnp-3271	81	27	and/or	and/or	CCONJ
fnp-3271	81	28	the	the	DET
fnp-3271	81	29	subclonal	subclonal	ADJ
fnp-3271	81	30	nature	nature	NOUN
fnp-3271	81	31	of	of	ADP
fnp-3271	81	32	their	their	PRON
fnp-3271	81	33	associated	associated	ADJ
fnp-3271	81	34	neoantigens	neoantigen	NOUN
fnp-3271	81	35	)	)	PUNCT
fnp-3271	81	36	,	,	PUNCT
fnp-3271	81	37	longer	long	ADJ
fnp-3271	81	38	treatment	treatment	NOUN
fnp-3271	81	39	exposure	exposure	NOUN
fnp-3271	81	40	or	or	CCONJ
fnp-3271	81	41	combinatorial	combinatorial	ADJ
fnp-3271	81	42	strategies	strategy	NOUN
fnp-3271	81	43	may	may	AUX
fnp-3271	81	44	improve	improve	VERB
fnp-3271	81	45	the	the	DET
fnp-3271	81	46	efficacy	efficacy	NOUN
fnp-3271	81	47	of	of	ADP
fnp-3271	81	48	checkpoint	checkpoint	NOUN
fnp-3271	81	49	blockade	blockade	NOUN
fnp-3271	81	50	for	for	ADP
fnp-3271	81	51	such	such	ADJ
fnp-3271	81	52	tumors	tumor	NOUN
fnp-3271	81	53	.	.	PUNCT
fnp-3271	82	1	importantly	importantly	ADV
fnp-3271	82	2	,	,	PUNCT
fnp-3271	82	3	and	and	CCONJ
fnp-3271	82	4	acknowledging	acknowledge	VERB
fnp-3271	82	5	that	that	PRON
fnp-3271	82	6	acquired	acquire	VERB
fnp-3271	82	7	mmr	mmr	PROPN
fnp-3271	82	8	deficiency	deficiency	NOUN
fnp-3271	82	9	occurs	occur	VERB
fnp-3271	82	10	in	in	ADP
fnp-3271	82	11	the	the	DET
fnp-3271	82	12	tumors	tumor	NOUN
fnp-3271	82	13	that	that	PRON
fnp-3271	82	14	are	be	AUX
fnp-3271	82	15	considered	consider	VERB
fnp-3271	82	16	as	as	ADP
fnp-3271	82	17	being	be	AUX
fnp-3271	82	18	the	the	DET
fnp-3271	82	19	most	most	ADV
fnp-3271	82	20	temozolomide	temozolomide	NOUN
fnp-3271	82	21	-	-	PUNCT
fnp-3271	82	22	sensitive	sensitive	ADJ
fnp-3271	82	23	,	,	PUNCT
fnp-3271	82	24	it	it	PRON
fnp-3271	82	25	is	be	AUX
fnp-3271	82	26	not	not	PART
fnp-3271	82	27	yet	yet	ADV
fnp-3271	82	28	clear	clear	ADJ
fnp-3271	82	29	whether	whether	SCONJ
fnp-3271	82	30	the	the	DET
fnp-3271	82	31	acquired	acquire	VERB
fnp-3271	82	32	mmr	mmr	PROPN
fnp-3271	82	33	deficiency	deficiency	NOUN
fnp-3271	82	34	outweighs	outweigh	VERB
fnp-3271	82	35	the	the	DET
fnp-3271	82	36	positive	positive	ADJ
fnp-3271	82	37	effects	effect	NOUN
fnp-3271	82	38	of	of	ADP
fnp-3271	82	39	temozolomide	temozolomide	NOUN
fnp-3271	82	40	in	in	ADP
fnp-3271	82	41	gliomas	glioma	NOUN
fnp-3271	82	42	.	.	PUNCT
fnp-3271	83	1	the	the	DET
fnp-3271	83	2	finding	finding	NOUN
fnp-3271	83	3	that	that	SCONJ
fnp-3271	83	4	mmr	mmr	PROPN
fnp-3271	83	5	-	-	PUNCT
fnp-3271	83	6	deficient	deficient	ADJ
fnp-3271	83	7	cells	cell	NOUN
fnp-3271	83	8	retain	retain	VERB
fnp-3271	83	9	sensitivity	sensitivity	NOUN
fnp-3271	83	10	to	to	ADP
fnp-3271	83	11	ccnu	ccnu	PROPN
fnp-3271	83	12	supports	support	VERB
fnp-3271	83	13	the	the	DET
fnp-3271	83	14	hypothesis	hypothesis	NOUN
fnp-3271	83	15	that	that	PRON
fnp-3271	83	16	hypermutation	hypermutation	NOUN
fnp-3271	83	17	reduces	reduce	VERB
fnp-3271	83	18	cellular	cellular	ADJ
fnp-3271	83	19	fitness	fitness	NOUN
fnp-3271	83	20	and	and	CCONJ
fnp-3271	83	21	tolerance	tolerance	NOUN
fnp-3271	83	22	to	to	ADP
fnp-3271	83	23	dna	dna	ADV
fnp-3271	83	24	-	-	PUNCT
fnp-3271	83	25	damaging	damaging	ADJ
fnp-3271	83	26	agents	agent	NOUN
fnp-3271	83	27	other	other	ADJ
fnp-3271	83	28	than	than	ADP
fnp-3271	83	29	temozolomide	temozolomide	NOUN
fnp-3271	83	30	.	.	PUNCT
fnp-3271	84	1	one	one	NUM
fnp-3271	84	2	of	of	ADP
fnp-3271	84	3	the	the	DET
fnp-3271	84	4	conclusions	conclusion	NOUN
fnp-3271	84	5	of	of	ADP
fnp-3271	84	6	the	the	DET
fnp-3271	84	7	authors	author	NOUN
fnp-3271	84	8	is	be	AUX
fnp-3271	84	9	that	that	PRON
fnp-3271	84	10	longitudinal	longitudinal	ADJ
fnp-3271	84	11	,	,	PUNCT
fnp-3271	84	12	molecular	molecular	ADJ
fnp-3271	84	13	analysis	analysis	NOUN
fnp-3271	84	14	of	of	ADP
fnp-3271	84	15	diffuse	diffuse	ADJ
fnp-3271	84	16	gliomas	glioma	NOUN
fnp-3271	84	17	can	can	AUX
fnp-3271	84	18	help	help	VERB
fnp-3271	84	19	improve	improve	VERB
fnp-3271	84	20	therapeutic	therapeutic	ADJ
fnp-3271	84	21	management	management	NOUN
fnp-3271	84	22	and	and	CCONJ
fnp-3271	84	23	,	,	PUNCT
fnp-3271	84	24	ultimately	ultimately	ADV
fnp-3271	84	25	,	,	PUNCT
fnp-3271	84	26	prognosis	prognosis	NOUN
fnp-3271	84	27	as	as	ADV
fnp-3271	84	28	well	well	ADV
fnp-3271	84	29	.	.	PUNCT
fnp-3271	85	1	topic	topic	NOUN
fnp-3271	85	2	5	5	NUM
fnp-3271	85	3	.	.	PUNCT
fnp-3271	85	4	immunological	immunological	ADJ
fnp-3271	85	5	aspects	aspect	NOUN
fnp-3271	85	6	of	of	ADP
fnp-3271	85	7	the	the	DET
fnp-3271	85	8	brain	brain	NOUN
fnp-3271	85	9	tumor	tumor	NOUN
fnp-3271	85	10	microenvironment	microenvironment	NOUN
fnp-3271	85	11	[	[	X
fnp-3271	85	12	5	5	NUM
fnp-3271	85	13	-	-	SYM
fnp-3271	85	14	7	7	NUM
fnp-3271	85	15	]	]	PUNCT
fnp-3271	85	16	in	in	ADP
fnp-3271	85	17	two	two	NUM
fnp-3271	85	18	papers	paper	NOUN
fnp-3271	85	19	published	publish	VERB
fnp-3271	85	20	back	back	ADV
fnp-3271	85	21	-	-	PUNCT
fnp-3271	85	22	to	to	AUX
fnp-3271	85	23	-	-	PUNCT
fnp-3271	85	24	back	back	NOUN
fnp-3271	85	25	in	in	ADP
fnp-3271	85	26	cell	cell	NOUN
fnp-3271	85	27	in	in	ADP
fnp-3271	85	28	june	june	PROPN
fnp-3271	85	29	2020	2020	NUM
fnp-3271	85	30	,	,	PUNCT
fnp-3271	85	31	the	the	DET
fnp-3271	85	32	authors	author	NOUN
fnp-3271	85	33	report	report	VERB
fnp-3271	85	34	on	on	ADP
fnp-3271	85	35	the	the	DET
fnp-3271	85	36	abundance	abundance	NOUN
fnp-3271	85	37	and	and	CCONJ
fnp-3271	85	38	heterogeneity	heterogeneity	NOUN
fnp-3271	85	39	of	of	ADP
fnp-3271	85	40	tissue	tissue	NOUN
fnp-3271	85	41	-	-	PUNCT
fnp-3271	85	42	resident	resident	NOUN
fnp-3271	85	43	and	and	CCONJ
fnp-3271	85	44	peripherally	peripherally	ADV
fnp-3271	85	45	recruited	recruit	VERB
fnp-3271	85	46	leucocytes	leucocyte	NOUN
fnp-3271	85	47	in	in	ADP
fnp-3271	85	48	glial	glial	ADJ
fnp-3271	85	49	and	and	CCONJ
fnp-3271	85	50	metastatic	metastatic	ADJ
fnp-3271	85	51	brain	brain	NOUN
fnp-3271	85	52	tumors	tumor	NOUN
fnp-3271	85	53	[	[	X
fnp-3271	85	54	5	5	NUM
fnp-3271	85	55	,	,	PUNCT
fnp-3271	85	56	6	6	NUM
fnp-3271	85	57	]	]	PUNCT
fnp-3271	85	58	.	.	PUNCT
fnp-3271	86	1	klemm	klemm	NOUN
fnp-3271	86	2	f	f	PROPN
fnp-3271	86	3	et	et	PROPN
fnp-3271	86	4	al	al	PROPN
fnp-3271	86	5	(	(	PUNCT
fnp-3271	86	6	last	last	ADJ
fnp-3271	86	7	author	author	NOUN
fnp-3271	86	8	joyce	joyce	PROPN
fnp-3271	86	9	j	j	PROPN
fnp-3271	87	1	[	[	X
fnp-3271	87	2	5	5	NUM
fnp-3271	87	3	]	]	PUNCT
fnp-3271	87	4	)	)	PUNCT
fnp-3271	87	5	comprehensively	comprehensively	ADV
fnp-3271	87	6	characterized	characterize	VERB
fnp-3271	87	7	the	the	DET
fnp-3271	87	8	tumor	tumor	NOUN
fnp-3271	87	9	microenvironment	microenvironment	NOUN
fnp-3271	87	10	(	(	PUNCT
fnp-3271	87	11	tme	tme	NOUN
fnp-3271	87	12	)	)	PUNCT
fnp-3271	87	13	of	of	ADP
fnp-3271	87	14	gliomas	glioma	NOUN
fnp-3271	87	15	and	and	CCONJ
fnp-3271	87	16	brain	brain	NOUN
fnp-3271	87	17	metastases	metastasis	NOUN
fnp-3271	87	18	using	use	VERB
fnp-3271	87	19	flow	flow	NOUN
fnp-3271	87	20	cytometry	cytometry	NOUN
fnp-3271	87	21	,	,	PUNCT
fnp-3271	87	22	rna	rna	NOUN
fnp-3271	87	23	sequencing	sequencing	NOUN
fnp-3271	87	24	,	,	PUNCT
fnp-3271	87	25	protein	protein	NOUN
fnp-3271	87	26	arrays	array	VERB
fnp-3271	87	27	,	,	PUNCT
fnp-3271	87	28	culture	culture	NOUN
fnp-3271	87	29	assays	assay	NOUN
fnp-3271	87	30	,	,	PUNCT
fnp-3271	87	31	and	and	CCONJ
fnp-3271	87	32	spatial	spatial	ADJ
fnp-3271	87	33	tissue	tissue	NOUN
fnp-3271	87	34	characterization	characterization	NOUN
fnp-3271	87	35	.	.	PUNCT
fnp-3271	88	1	they	they	PRON
fnp-3271	88	2	found	find	VERB
fnp-3271	88	3	that	that	SCONJ
fnp-3271	88	4	‘	'	PUNCT
fnp-3271	88	5	education	education	NOUN
fnp-3271	88	6	’	'	PUNCT
fnp-3271	88	7	of	of	ADP
fnp-3271	88	8	immune	immune	ADJ
fnp-3271	88	9	cell	cell	NOUN
fnp-3271	88	10	types	type	NOUN
fnp-3271	88	11	in	in	ADP
fnp-3271	88	12	the	the	DET
fnp-3271	88	13	tme	tme	NOUN
fnp-3271	88	14	depends	depend	VERB
fnp-3271	88	15	on	on	ADP
fnp-3271	88	16	tumor	tumor	NOUN
fnp-3271	88	17	origin	origin	NOUN
fnp-3271	88	18	and	and	CCONJ
fnp-3271	88	19	idh	idh	VERB
fnp-3271	88	20	mutational	mutational	ADJ
fnp-3271	88	21	status	status	NOUN
fnp-3271	88	22	,	,	PUNCT
fnp-3271	88	23	with	with	ADP
fnp-3271	88	24	pronounced	pronounce	VERB
fnp-3271	88	25	differences	difference	NOUN
fnp-3271	88	26	in	in	ADP
fnp-3271	88	27	proportional	proportional	ADJ
fnp-3271	88	28	abundance	abundance	NOUN
fnp-3271	88	29	of	of	ADP
fnp-3271	88	30	tissue	tissue	NOUN
fnp-3271	88	31	-	-	PUNCT
fnp-3271	88	32	resident	resident	NOUN
fnp-3271	88	33	microglia	microglia	NOUN
fnp-3271	88	34	,	,	PUNCT
fnp-3271	88	35	infiltrating	infiltrating	ADJ
fnp-3271	88	36	monocyte	monocyte	ADJ
fnp-3271	88	37	-	-	PUNCT
fnp-3271	88	38	derived	derive	VERB
fnp-3271	88	39	macrophages	macrophage	NOUN
fnp-3271	88	40	,	,	PUNCT
fnp-3271	88	41	neutrophils	neutrophil	NOUN
fnp-3271	88	42	,	,	PUNCT
fnp-3271	88	43	and	and	CCONJ
fnp-3271	88	44	t	t	NOUN
fnp-3271	88	45	cells	cell	NOUN
fnp-3271	88	46	.	.	PUNCT
fnp-3271	89	1	friebel	friebel	PROPN
fnp-3271	89	2	b	b	PROPN
fnp-3271	89	3	,	,	PUNCT
fnp-3271	89	4	kapolou	kapolou	PROPN
fnp-3271	89	5	k	k	PROPN
fnp-3271	89	6	,	,	PUNCT
fnp-3271	89	7	et	et	PROPN
fnp-3271	89	8	al	al	PROPN
fnp-3271	89	9	(	(	PUNCT
fnp-3271	89	10	last	last	ADJ
fnp-3271	89	11	authors	author	NOUN
fnp-3271	89	12	neidert	neidert	PROPN
fnp-3271	89	13	mc	mc	PROPN
fnp-3271	89	14	,	,	PUNCT
fnp-3271	89	15	becher	becher	PROPN
fnp-3271	89	16	b	b	PROPN
fnp-3271	90	1	[	[	X
fnp-3271	90	2	6	6	NUM
fnp-3271	90	3	]	]	PUNCT
fnp-3271	90	4	)	)	PUNCT
fnp-3271	90	5	mapped	map	VERB
fnp-3271	90	6	the	the	DET
fnp-3271	90	7	leukocyte	leukocyte	ADJ
fnp-3271	90	8	landscape	landscape	NOUN
fnp-3271	90	9	of	of	ADP
fnp-3271	90	10	brain	brain	NOUN
fnp-3271	90	11	tumors	tumor	NOUN
fnp-3271	90	12	using	use	VERB
fnp-3271	90	13	high	high	ADJ
fnp-3271	90	14	-	-	PUNCT
fnp-3271	90	15	dimensional	dimensional	ADJ
fnp-3271	90	16	single	single	ADJ
fnp-3271	90	17	-	-	PUNCT
fnp-3271	90	18	cell	cell	NOUN
fnp-3271	90	19	profiling	profiling	NOUN
fnp-3271	90	20	(	(	PUNCT
fnp-3271	90	21	cytof	cytof	NOUN
fnp-3271	90	22	)	)	PUNCT
fnp-3271	90	23	and	and	CCONJ
fnp-3271	90	24	found	find	VERB
fnp-3271	90	25	a	a	DET
fnp-3271	90	26	heterogeneous	heterogeneous	ADJ
fnp-3271	90	27	composition	composition	NOUN
fnp-3271	90	28	of	of	ADP
fnp-3271	90	29	tissue	tissue	NOUN
fnp-3271	90	30	-	-	PUNCT
fnp-3271	90	31	resident	resident	NOUN
fnp-3271	90	32	and	and	CCONJ
fnp-3271	90	33	invading	invade	VERB
fnp-3271	90	34	immune	immune	ADJ
fnp-3271	90	35	cells	cell	NOUN
fnp-3271	90	36	within	within	ADP
fnp-3271	90	37	the	the	DET
fnp-3271	90	38	tme	tme	NOUN
fnp-3271	90	39	,	,	PUNCT
fnp-3271	90	40	allowing	allow	VERB
fnp-3271	90	41	for	for	ADP
fnp-3271	90	42	a	a	DET
fnp-3271	90	43	clear	clear	ADJ
fnp-3271	90	44	distinction	distinction	NOUN
fnp-3271	90	45	between	between	ADP
fnp-3271	90	46	gliomas	glioma	NOUN
fnp-3271	90	47	and	and	CCONJ
fnp-3271	90	48	brain	brain	NOUN
fnp-3271	90	49	metastases	metastasis	NOUN
fnp-3271	90	50	.	.	PUNCT
fnp-3271	91	1	gliomas	glioma	NOUN
fnp-3271	91	2	typically	typically	ADV
fnp-3271	91	3	showed	show	VERB
fnp-3271	91	4	tissue	tissue	NOUN
fnp-3271	91	5	-	-	PUNCT
fnp-3271	91	6	resident	resident	NOUN
fnp-3271	91	7	,	,	PUNCT
fnp-3271	91	8	reactive	reactive	ADJ
fnp-3271	91	9	microglia	microglia	NOUN
fnp-3271	91	10	,	,	PUNCT
fnp-3271	91	11	whereas	whereas	SCONJ
fnp-3271	91	12	tissue	tissue	NOUN
fnp-3271	91	13	-	-	PUNCT
fnp-3271	91	14	invading	invade	VERB
fnp-3271	91	15	leukocytes	leukocyte	NOUN
fnp-3271	91	16	accumulated	accumulate	VERB
fnp-3271	91	17	in	in	ADP
fnp-3271	91	18	brain	brain	NOUN
fnp-3271	91	19	metastases	metastasis	NOUN
fnp-3271	91	20	.	.	PUNCT
fnp-3271	92	1	tissue	tissue	NOUN
fnp-3271	92	2	-	-	PUNCT
fnp-3271	92	3	invading	invade	VERB
fnp-3271	92	4	tumor	tumor	NOUN
fnp-3271	92	5	-	-	PUNCT
fnp-3271	92	6	associated	associate	VERB
fnp-3271	92	7	macrophages	macrophage	NOUN
fnp-3271	92	8	showed	show	VERB
fnp-3271	92	9	a	a	DET
fnp-3271	92	10	distinctive	distinctive	ADJ
fnp-3271	92	11	signature	signature	NOUN
fnp-3271	92	12	trajectory	trajectory	NOUN
fnp-3271	92	13	,	,	PUNCT
fnp-3271	92	14	revealing	reveal	VERB
fnp-3271	92	15	tumor	tumor	NOUN
fnp-3271	92	16	-	-	PUNCT
fnp-3271	92	17	driven	drive	VERB
fnp-3271	92	18	instruction	instruction	NOUN
fnp-3271	92	19	along	along	ADP
fnp-3271	92	20	with	with	ADP
fnp-3271	92	21	contrasting	contrast	VERB
fnp-3271	92	22	lymphocyte	lymphocyte	ADJ
fnp-3271	92	23	activation	activation	NOUN
fnp-3271	92	24	and	and	CCONJ
fnp-3271	92	25	exhaustion	exhaustion	NOUN
fnp-3271	92	26	.	.	PUNCT
fnp-3271	93	1	indeed	indeed	ADV
fnp-3271	93	2	,	,	PUNCT
fnp-3271	93	3	these	these	DET
fnp-3271	93	4	integrated	integrate	VERB
fnp-3271	93	5	analyses	analysis	NOUN
fnp-3271	93	6	further	far	ADV
fnp-3271	93	7	elucidate	elucidate	VERB
fnp-3271	93	8	the	the	DET
fnp-3271	93	9	multifaceted	multifaceted	ADJ
fnp-3271	93	10	immune	immune	ADJ
fnp-3271	93	11	cell	cell	NOUN
fnp-3271	93	12	activation	activation	NOUN
fnp-3271	93	13	within	within	ADP
fnp-3271	93	14	brain	brain	NOUN
fnp-3271	93	15	tumors	tumor	NOUN
fnp-3271	93	16	and	and	CCONJ
fnp-3271	93	17	are	be	AUX
fnp-3271	93	18	instrumental	instrumental	ADJ
fnp-3271	93	19	for	for	ADP
fnp-3271	93	20	a	a	DET
fnp-3271	93	21	rational	rational	ADJ
fnp-3271	93	22	design	design	NOUN
fnp-3271	93	23	of	of	ADP
fnp-3271	93	24	more	more	ADV
fnp-3271	93	25	efficacious	efficacious	ADJ
fnp-3271	93	26	,	,	PUNCT
fnp-3271	93	27	targeted	target	VERB
fnp-3271	93	28	immunotherapy	immunotherapy	NOUN
fnp-3271	93	29	strategies	strategy	NOUN
fnp-3271	93	30	.	.	PUNCT
fnp-3271	94	1	in	in	ADP
fnp-3271	94	2	the	the	DET
fnp-3271	94	3	study	study	NOUN
fnp-3271	94	4	published	publish	VERB
fnp-3271	94	5	in	in	ADP
fnp-3271	94	6	cancer	cancer	NOUN
fnp-3271	94	7	discovery	discovery	NOUN
fnp-3271	94	8	,	,	PUNCT
fnp-3271	94	9	bayik	bayik	NOUN
fnp-3271	94	10	d	d	X
fnp-3271	94	11	et	et	PROPN
fnp-3271	94	12	al	al	PROPN
fnp-3271	94	13	(	(	PUNCT
fnp-3271	94	14	last	last	ADJ
fnp-3271	94	15	author	author	NOUN
fnp-3271	94	16	lathia	lathia	PROPN
fnp-3271	94	17	jd	jd	PROPN
fnp-3271	94	18	)	)	PUNCT
fnp-3271	94	19	used	use	VERB
fnp-3271	94	20	mouse	mouse	NOUN
fnp-3271	94	21	models	model	NOUN
fnp-3271	94	22	to	to	PART
fnp-3271	94	23	study	study	VERB
fnp-3271	94	24	the	the	DET
fnp-3271	94	25	presence	presence	NOUN
fnp-3271	94	26	of	of	ADP
fnp-3271	94	27	monocytic	monocytic	ADJ
fnp-3271	94	28	versus	versus	ADP
fnp-3271	94	29	granulocytic	granulocytic	ADJ
fnp-3271	94	30	myeloid	myeloid	NOUN
fnp-3271	94	31	-	-	PUNCT
fnp-3271	94	32	derived	derive	VERB
fnp-3271	94	33	suppressor	suppressor	NOUN
fnp-3271	94	34	cells	cell	NOUN
fnp-3271	94	35	(	(	PUNCT
fnp-3271	94	36	mmdscs	mmdsc	NOUN
fnp-3271	94	37	/	/	SYM
fnp-3271	94	38	gmdscs	gmdsc	NOUN
fnp-3271	94	39	)	)	PUNCT
fnp-3271	95	1	[	[	X
fnp-3271	95	2	7	7	NUM
fnp-3271	95	3	]	]	PUNCT
fnp-3271	95	4	.	.	PUNCT
fnp-3271	96	1	mdscs	mdsc	NOUN
fnp-3271	96	2	are	be	AUX
fnp-3271	96	3	known	know	VERB
fnp-3271	96	4	to	to	PART
fnp-3271	96	5	be	be	AUX
fnp-3271	96	6	elevated	elevate	VERB
fnp-3271	96	7	in	in	ADP
fnp-3271	96	8	blood	blood	NOUN
fnp-3271	96	9	and	and	CCONJ
fnp-3271	96	10	tumor	tumor	NOUN
fnp-3271	96	11	tissue	tissue	NOUN
fnp-3271	96	12	of	of	ADP
fnp-3271	96	13	patients	patient	NOUN
fnp-3271	96	14	with	with	ADP
fnp-3271	96	15	glioblastoma	glioblastoma	NOUN
fnp-3271	96	16	and	and	CCONJ
fnp-3271	96	17	for	for	ADP
fnp-3271	96	18	blocking	block	VERB
fnp-3271	96	19	antitumor	antitumor	PROPN
fnp-3271	96	20	immunity	immunity	NOUN
fnp-3271	96	21	.	.	PUNCT
fnp-3271	97	1	bayik	bayik	PROPN
fnp-3271	98	1	d	d	X
fnp-3271	98	2	et	et	PROPN
fnp-3271	98	3	al	al	PROPN
fnp-3271	98	4	observed	observe	VERB
fnp-3271	98	5	that	that	SCONJ
fnp-3271	98	6	,	,	PUNCT
fnp-3271	98	7	in	in	ADP
fnp-3271	98	8	their	their	PRON
fnp-3271	98	9	models	model	NOUN
fnp-3271	98	10	,	,	PUNCT
fnp-3271	98	11	mmdscs	mmdsc	NOUN
fnp-3271	98	12	were	be	AUX
fnp-3271	98	13	enriched	enrich	VERB
fnp-3271	98	14	in	in	ADP
fnp-3271	98	15	the	the	DET
fnp-3271	98	16	male	male	ADJ
fnp-3271	98	17	tumors	tumor	NOUN
fnp-3271	98	18	,	,	PUNCT
fnp-3271	98	19	whereas	whereas	SCONJ
fnp-3271	98	20	gmdscs	gmdsc	NOUN
fnp-3271	98	21	were	be	AUX
fnp-3271	98	22	elevated	elevate	VERB
fnp-3271	98	23	in	in	ADP
fnp-3271	98	24	the	the	DET
fnp-3271	98	25	blood	blood	NOUN
fnp-3271	98	26	of	of	ADP
fnp-3271	98	27	females	female	NOUN
fnp-3271	98	28	.	.	PUNCT
fnp-3271	99	1	furthermore	furthermore	ADV
fnp-3271	99	2	,	,	PUNCT
fnp-3271	99	3	depletion	depletion	NOUN
fnp-3271	99	4	of	of	ADP
fnp-3271	99	5	gmdscs	gmdscs	PROPN
fnp-3271	99	6	extended	extended	ADJ
fnp-3271	99	7	survival	survival	NOUN
fnp-3271	99	8	only	only	ADV
fnp-3271	99	9	in	in	ADP
fnp-3271	99	10	female	female	ADJ
fnp-3271	99	11	mice	mouse	NOUN
fnp-3271	99	12	.	.	PUNCT
fnp-3271	100	1	using	use	VERB
fnp-3271	100	2	gene	gene	NOUN
fnp-3271	100	3	-	-	PUNCT
fnp-3271	100	4	expression	expression	NOUN
fnp-3271	100	5	signatures	signature	NOUN
fnp-3271	100	6	coupled	couple	VERB
fnp-3271	100	7	with	with	ADP
fnp-3271	100	8	network	network	NOUN
fnp-3271	100	9	medicine	medicine	NOUN
fnp-3271	100	10	analysis	analysis	NOUN
fnp-3271	100	11	,	,	PUNCT
fnp-3271	100	12	the	the	DET
fnp-3271	100	13	authors	author	NOUN
fnp-3271	100	14	demonstrated	demonstrate	VERB
fnp-3271	100	15	that	that	SCONJ
fnp-3271	100	16	mmdscs	mmdsc	NOUN
fnp-3271	100	17	could	could	AUX
fnp-3271	100	18	be	be	AUX
fnp-3271	100	19	targeted	target	VERB
fnp-3271	100	20	with	with	ADP
fnp-3271	100	21	antiproliferative	antiproliferative	ADJ
fnp-3271	100	22	agents	agent	NOUN
fnp-3271	100	23	in	in	ADP
fnp-3271	100	24	males	male	NOUN
fnp-3271	100	25	,	,	PUNCT
fnp-3271	100	26	whereas	whereas	SCONJ
fnp-3271	100	27	gmdsc	gmdsc	NOUN
fnp-3271	100	28	function	function	NOUN
fnp-3271	100	29	could	could	AUX
fnp-3271	100	30	be	be	AUX
fnp-3271	100	31	inhibited	inhibit	VERB
fnp-3271	100	32	by	by	ADP
fnp-3271	100	33	il1β	il1β	PROPN
fnp-3271	100	34	blockade	blockade	NOUN
fnp-3271	100	35	in	in	ADP
fnp-3271	100	36	females	female	NOUN
fnp-3271	100	37	.	.	PUNCT
fnp-3271	101	1	analysis	analysis	NOUN
fnp-3271	101	2	of	of	ADP
fnp-3271	101	3	patient	patient	ADJ
fnp-3271	101	4	data	datum	NOUN
fnp-3271	101	5	confirmed	confirm	VERB
fnp-3271	101	6	that	that	SCONJ
fnp-3271	101	7	proliferating	proliferate	VERB
fnp-3271	101	8	mmdscs	mmdsc	NOUN
fnp-3271	101	9	were	be	AUX
fnp-3271	101	10	predominant	predominant	ADJ
fnp-3271	101	11	in	in	ADP
fnp-3271	101	12	male	male	ADJ
fnp-3271	101	13	tumors	tumor	NOUN
fnp-3271	101	14	and	and	CCONJ
fnp-3271	101	15	that	that	SCONJ
fnp-3271	101	16	a	a	DET
fnp-3271	101	17	high	high	ADJ
fnp-3271	101	18	gmdsc	gmdsc	NOUN
fnp-3271	101	19	/	/	SYM
fnp-3271	101	20	il1β	il1β	PROPN
fnp-3271	101	21	gene	gene	NOUN
fnp-3271	101	22	signature	signature	NOUN
fnp-3271	101	23	correlated	correlate	VERB
fnp-3271	101	24	with	with	ADP
fnp-3271	101	25	poor	poor	ADJ
fnp-3271	101	26	prognosis	prognosis	NOUN
fnp-3271	101	27	in	in	ADP
fnp-3271	101	28	female	female	ADJ
fnp-3271	101	29	patients	patient	NOUN
fnp-3271	101	30	.	.	PUNCT
fnp-3271	102	1	interestingly	interestingly	ADV
fnp-3271	102	2	,	,	PUNCT
fnp-3271	102	3	there	there	PRON
fnp-3271	102	4	is	be	VERB
fnp-3271	102	5	a	a	DET
fnp-3271	102	6	quite	quite	ADV
fnp-3271	102	7	striking	striking	ADJ
fnp-3271	102	8	sex	sex	NOUN
fnp-3271	102	9	disparity	disparity	NOUN
fnp-3271	102	10	for	for	ADP
fnp-3271	102	11	glioblastomas	glioblastoma	NOUN
fnp-3271	102	12	at	at	ADP
fnp-3271	102	13	other	other	ADJ
fnp-3271	102	14	levels	level	NOUN
fnp-3271	102	15	as	as	ADV
fnp-3271	102	16	well	well	ADV
fnp-3271	102	17	.	.	PUNCT
fnp-3271	103	1	for	for	ADP
fnp-3271	103	2	example	example	NOUN
fnp-3271	103	3	,	,	PUNCT
fnp-3271	103	4	the	the	DET
fnp-3271	103	5	incidence	incidence	NOUN
fnp-3271	103	6	of	of	ADP
fnp-3271	103	7	glioblastoma	glioblastoma	NOUN
fnp-3271	103	8	is	be	AUX
fnp-3271	103	9	significantly	significantly	ADV
fnp-3271	103	10	higher	high	ADJ
fnp-3271	103	11	in	in	ADP
fnp-3271	103	12	males	male	NOUN
fnp-3271	103	13	than	than	ADP
fnp-3271	103	14	in	in	ADP
fnp-3271	103	15	females	female	NOUN
fnp-3271	103	16	(	(	PUNCT
fnp-3271	103	17	incidence	incidence	NOUN
fnp-3271	103	18	rate	rate	NOUN
fnp-3271	103	19	ratio	ratio	NOUN
fnp-3271	103	20	1.59:1	1.59:1	NUM
fnp-3271	103	21	)	)	PUNCT
fnp-3271	103	22	(	(	PUNCT
fnp-3271	103	23	figure	figure	NOUN
fnp-3271	103	24	2	2	NUM
fnp-3271	103	25	)	)	PUNCT
fnp-3271	103	26	,	,	PUNCT
fnp-3271	103	27	and	and	CCONJ
fnp-3271	103	28	there	there	PRON
fnp-3271	103	29	is	be	VERB
fnp-3271	103	30	a	a	DET
fnp-3271	103	31	survival	survival	NOUN
fnp-3271	103	32	advantage	advantage	NOUN
fnp-3271	103	33	for	for	ADP
fnp-3271	103	34	females	female	NOUN
fnp-3271	103	35	with	with	ADP
fnp-3271	103	36	glioblastoma	glioblastoma	NOUN
fnp-3271	103	37	independent	independent	ADJ
fnp-3271	103	38	of	of	ADP
fnp-3271	103	39	treatment	treatment	NOUN
fnp-3271	103	40	,	,	PUNCT
fnp-3271	103	41	age	age	NOUN
fnp-3271	103	42	,	,	PUNCT
fnp-3271	103	43	karnofsky	karnofsky	ADJ
fnp-3271	103	44	performance	performance	NOUN
fnp-3271	103	45	status	status	NOUN
fnp-3271	103	46	(	(	PUNCT
fnp-3271	103	47	kps	kps	PROPN
fnp-3271	103	48	)	)	PUNCT
fnp-3271	103	49	,	,	PUNCT
fnp-3271	103	50	or	or	CCONJ
fnp-3271	103	51	idh	idh	NOUN
fnp-3271	103	52	mutation	mutation	NOUN
fnp-3271	103	53	status	status	NOUN
fnp-3271	103	54	[	[	X
fnp-3271	103	55	21	21	NUM
fnp-3271	103	56	,	,	PUNCT
fnp-3271	103	57	22	22	NUM
fnp-3271	103	58	]	]	PUNCT
fnp-3271	103	59	.	.	PUNCT
fnp-3271	104	1	the	the	DET
fnp-3271	104	2	work	work	NOUN
fnp-3271	104	3	of	of	ADP
fnp-3271	104	4	bayik	bayik	NOUN
fnp-3271	104	5	et	et	PROPN
fnp-3271	104	6	al	al	PROPN
fnp-3271	104	7	may	may	AUX
fnp-3271	104	8	explain	explain	VERB
fnp-3271	104	9	some	some	PRON
fnp-3271	104	10	of	of	ADP
fnp-3271	104	11	such	such	ADJ
fnp-3271	104	12	sex	sex	NOUN
fnp-3271	104	13	differences	difference	NOUN
fnp-3271	104	14	in	in	ADP
fnp-3271	104	15	patients	patient	NOUN
fnp-3271	104	16	with	with	ADP
fnp-3271	104	17	glioblastoma	glioblastoma	NOUN
fnp-3271	104	18	and	and	CCONJ
fnp-3271	104	19	indicate	indicate	VERB
fnp-3271	104	20	that	that	SCONJ
fnp-3271	104	21	(	(	PUNCT
fnp-3271	104	22	immuno)therapeutic	immuno)therapeutic	ADJ
fnp-3271	104	23	approaches	approach	NOUN
fnp-3271	104	24	should	should	AUX
fnp-3271	104	25	be	be	AUX
fnp-3271	104	26	adapted	adapt	VERB
fnp-3271	104	27	to	to	ADP
fnp-3271	104	28	the	the	DET
fnp-3271	104	29	patient	patient	NOUN
fnp-3271	104	30	’s	’s	PART
fnp-3271	104	31	gender	gender	NOUN
fnp-3271	104	32	.	.	PUNCT
fnp-3271	105	1	fig	fig	NOUN
fnp-3271	105	2	.	.	PUNCT
fnp-3271	106	1	2	2	X
fnp-3271	106	2	.	.	X
fnp-3271	106	3	incidence	incidence	NOUN
fnp-3271	106	4	rate	rate	NOUN
fnp-3271	106	5	ratios	ratio	NOUN
fnp-3271	106	6	by	by	ADP
fnp-3271	106	7	sex	sex	NOUN
fnp-3271	106	8	for	for	ADP
fnp-3271	106	9	primary	primary	ADJ
fnp-3271	106	10	brain	brain	NOUN
fnp-3271	106	11	tumors	tumor	NOUN
fnp-3271	106	12	.	.	PUNCT
fnp-3271	107	1	the	the	DET
fnp-3271	107	2	incidence	incidence	NOUN
fnp-3271	107	3	of	of	ADP
fnp-3271	107	4	most	most	ADJ
fnp-3271	107	5	gliomas	glioma	NOUN
fnp-3271	107	6	and	and	CCONJ
fnp-3271	107	7	embryonal	embryonal	ADJ
fnp-3271	107	8	brain	brain	NOUN
fnp-3271	107	9	tumors	tumor	NOUN
fnp-3271	107	10	is	be	AUX
fnp-3271	107	11	significantly	significantly	ADV
fnp-3271	107	12	higher	high	ADJ
fnp-3271	107	13	in	in	ADP
fnp-3271	107	14	males	male	NOUN
fnp-3271	107	15	.	.	PUNCT
fnp-3271	108	1	for	for	ADP
fnp-3271	108	2	glioblastomas	glioblastoma	NOUN
fnp-3271	108	3	the	the	DET
fnp-3271	108	4	male	male	NOUN
fnp-3271	108	5	:	:	PUNCT
fnp-3271	108	6	female	female	ADJ
fnp-3271	108	7	ratio	ratio	NOUN
fnp-3271	108	8	is	be	AUX
fnp-3271	108	9	1.59:1	1.59:1	NUM
fnp-3271	108	10	[	[	X
fnp-3271	108	11	21	21	NUM
fnp-3271	108	12	]	]	PUNCT
fnp-3271	108	13	.	.	PUNCT
fnp-3271	109	1	furthermore	furthermore	ADV
fnp-3271	109	2	,	,	PUNCT
fnp-3271	109	3	there	there	PRON
fnp-3271	109	4	is	be	VERB
fnp-3271	109	5	a	a	DET
fnp-3271	109	6	female	female	ADJ
fnp-3271	109	7	survival	survival	NOUN
fnp-3271	109	8	advantage	advantage	NOUN
fnp-3271	109	9	for	for	ADP
fnp-3271	109	10	patients	patient	NOUN
fnp-3271	109	11	with	with	ADP
fnp-3271	109	12	glioblastoma	glioblastoma	NOUN
fnp-3271	109	13	independent	independent	ADJ
fnp-3271	109	14	of	of	ADP
fnp-3271	109	15	treatment	treatment	NOUN
fnp-3271	109	16	,	,	PUNCT
fnp-3271	109	17	age	age	NOUN
fnp-3271	109	18	,	,	PUNCT
fnp-3271	109	19	karnofsky	karnofsky	ADJ
fnp-3271	109	20	performance	performance	NOUN
fnp-3271	109	21	status	status	NOUN
fnp-3271	109	22	(	(	PUNCT
fnp-3271	109	23	kps	kps	PROPN
fnp-3271	109	24	)	)	PUNCT
fnp-3271	109	25	,	,	PUNCT
fnp-3271	109	26	or	or	CCONJ
fnp-3271	109	27	idh	idh	NOUN
fnp-3271	109	28	mutation	mutation	NOUN
fnp-3271	109	29	status	status	NOUN
fnp-3271	109	30	[	[	X
fnp-3271	109	31	22	22	NUM
fnp-3271	109	32	]	]	PUNCT
fnp-3271	109	33	.	.	PUNCT
fnp-3271	110	1	the	the	DET
fnp-3271	110	2	work	work	NOUN
fnp-3271	110	3	of	of	ADP
fnp-3271	110	4	bayik	bayik	NOUN
fnp-3271	110	5	et	et	PROPN
fnp-3271	110	6	al	al	PROPN
fnp-3271	110	7	may	may	AUX
fnp-3271	110	8	provide	provide	VERB
fnp-3271	110	9	support	support	NOUN
fnp-3271	110	10	for	for	ADP
fnp-3271	110	11	the	the	DET
fnp-3271	110	12	hypothesis	hypothesis	NOUN
fnp-3271	110	13	that	that	PRON
fnp-3271	110	14	differences	difference	NOUN
fnp-3271	110	15	in	in	ADP
fnp-3271	110	16	immune	immune	ADJ
fnp-3271	110	17	system	system	NOUN
fnp-3271	110	18	functions	function	NOUN
fnp-3271	110	19	contribute	contribute	VERB
fnp-3271	110	20	to	to	ADP
fnp-3271	110	21	these	these	DET
fnp-3271	110	22	sex	sex	NOUN
fnp-3271	110	23	differences	difference	NOUN
fnp-3271	110	24	and	and	CCONJ
fnp-3271	110	25	that	that	SCONJ
fnp-3271	110	26	(	(	PUNCT
fnp-3271	110	27	immuno)therapeutic	immuno)therapeutic	ADJ
fnp-3271	110	28	approaches	approach	NOUN
fnp-3271	110	29	should	should	AUX
fnp-3271	110	30	be	be	AUX
fnp-3271	110	31	adapted	adapt	VERB
fnp-3271	110	32	to	to	ADP
fnp-3271	110	33	the	the	DET
fnp-3271	110	34	patient	patient	NOUN
fnp-3271	110	35	’s	’s	PART
fnp-3271	110	36	gender	gender	NOUN
fnp-3271	110	37	.	.	PUNCT
fnp-3271	111	1	figure	figure	NOUN
fnp-3271	111	2	based	base	VERB
fnp-3271	111	3	on	on	ADP
fnp-3271	111	4	ostrom	ostrom	PROPN
fnp-3271	111	5	qt	qt	PROPN
fnp-3271	111	6	et	et	PROPN
fnp-3271	111	7	al	al	PROPN
fnp-3271	111	8	(	(	PUNCT
fnp-3271	111	9	2020	2020	NUM
fnp-3271	111	10	)	)	PUNCT
fnp-3271	112	1	[	[	X
fnp-3271	112	2	21	21	NUM
fnp-3271	112	3	]	]	PUNCT
fnp-3271	112	4	.	.	PUNCT
fnp-3271	113	1	*	*	PUNCT
fnp-3271	113	2	=	=	PUNCT
fnp-3271	113	3	p<0.05	p<0.05	NOUN
fnp-3271	113	4	.	.	PUNCT
fnp-3271	113	5	topic	topic	NOUN
fnp-3271	113	6	6	6	NUM
fnp-3271	113	7	.	.	PUNCT
fnp-3271	114	1	lymphatic	lymphatic	ADJ
fnp-3271	114	2	drainage	drainage	NOUN
fnp-3271	114	3	enables	enable	VERB
fnp-3271	114	4	brain	brain	VERB
fnp-3271	114	5	tumor	tumor	NOUN
fnp-3271	114	6	surveillance	surveillance	NOUN
fnp-3271	114	7	[	[	X
fnp-3271	114	8	8	8	NUM
fnp-3271	114	9	,	,	PUNCT
fnp-3271	114	10	9	9	NUM
fnp-3271	114	11	]	]	PUNCT
fnp-3271	114	12	the	the	DET
fnp-3271	114	13	central	central	ADJ
fnp-3271	114	14	nervous	nervous	ADJ
fnp-3271	114	15	system	system	NOUN
fnp-3271	114	16	(	(	PUNCT
fnp-3271	114	17	cns	cns	NOUN
fnp-3271	114	18	)	)	PUNCT
fnp-3271	114	19	has	have	AUX
fnp-3271	114	20	long	long	ADV
fnp-3271	114	21	been	be	AUX
fnp-3271	114	22	considered	consider	VERB
fnp-3271	114	23	as	as	ADP
fnp-3271	114	24	lacking	lack	VERB
fnp-3271	114	25	lymphatic	lymphatic	ADJ
fnp-3271	114	26	drainage	drainage	NOUN
fnp-3271	114	27	,	,	PUNCT
fnp-3271	114	28	a	a	DET
fnp-3271	114	29	situation	situation	NOUN
fnp-3271	114	30	which	which	PRON
fnp-3271	114	31	could	could	AUX
fnp-3271	114	32	then	then	ADV
fnp-3271	114	33	contribute	contribute	VERB
fnp-3271	114	34	to	to	ADP
fnp-3271	114	35	the	the	DET
fnp-3271	114	36	generally	generally	ADV
fnp-3271	114	37	limited	limited	ADJ
fnp-3271	114	38	immunological	immunological	ADJ
fnp-3271	114	39	response	response	NOUN
fnp-3271	114	40	in	in	ADP
fnp-3271	114	41	glioblastomas	glioblastoma	NOUN
fnp-3271	114	42	and	and	CCONJ
fnp-3271	114	43	other	other	ADJ
fnp-3271	114	44	brain	brain	NOUN
fnp-3271	114	45	tumors	tumor	NOUN
fnp-3271	114	46	.	.	PUNCT
fnp-3271	115	1	later	later	ADV
fnp-3271	115	2	on	on	ADV
fnp-3271	115	3	,	,	PUNCT
fnp-3271	115	4	however	however	ADV
fnp-3271	115	5	,	,	PUNCT
fnp-3271	115	6	it	it	PRON
fnp-3271	115	7	became	become	VERB
fnp-3271	115	8	clear	clear	ADJ
fnp-3271	115	9	that	that	SCONJ
fnp-3271	115	10	lymphatic	lymphatic	ADJ
fnp-3271	115	11	vessels	vessel	NOUN
fnp-3271	115	12	are	be	AUX
fnp-3271	115	13	present	present	ADJ
fnp-3271	115	14	in	in	ADP
fnp-3271	115	15	the	the	DET
fnp-3271	115	16	intracranial	intracranial	ADJ
fnp-3271	115	17	meninges	meninge	NOUN
fnp-3271	115	18	along	along	ADP
fnp-3271	115	19	the	the	DET
fnp-3271	115	20	dural	dural	ADJ
fnp-3271	115	21	sinuses	sinus	NOUN
fnp-3271	115	22	.	.	PUNCT
fnp-3271	116	1	these	these	DET
fnp-3271	116	2	lymphatics	lymphatic	NOUN
fnp-3271	116	3	drain	drain	VERB
fnp-3271	116	4	brain	brain	NOUN
fnp-3271	116	5	-	-	PUNCT
fnp-3271	116	6	derived	derive	VERB
fnp-3271	116	7	soluble	soluble	ADJ
fnp-3271	116	8	waste	waste	NOUN
fnp-3271	116	9	to	to	ADP
fnp-3271	116	10	deep	deep	ADJ
fnp-3271	116	11	cervical	cervical	ADJ
fnp-3271	116	12	lymph	lymph	NOUN
fnp-3271	116	13	nodes	node	NOUN
fnp-3271	116	14	,	,	PUNCT
fnp-3271	116	15	thereby	thereby	ADV
fnp-3271	116	16	directly	directly	ADV
fnp-3271	116	17	connecting	connect	VERB
fnp-3271	116	18	the	the	DET
fnp-3271	116	19	brain	brain	NOUN
fnp-3271	116	20	with	with	ADP
fnp-3271	116	21	the	the	DET
fnp-3271	116	22	peripheral	peripheral	ADJ
fnp-3271	116	23	immune	immune	ADJ
fnp-3271	116	24	system	system	NOUN
fnp-3271	116	25	.	.	PUNCT
fnp-3271	117	1	recent	recent	ADJ
fnp-3271	117	2	studies	study	NOUN
fnp-3271	117	3	also	also	ADV
fnp-3271	117	4	demonstrated	demonstrate	VERB
fnp-3271	117	5	the	the	DET
fnp-3271	117	6	presence	presence	NOUN
fnp-3271	117	7	of	of	ADP
fnp-3271	117	8	meningeal	meningeal	ADJ
fnp-3271	117	9	lymphatics	lymphatic	NOUN
fnp-3271	117	10	along	along	ADP
fnp-3271	117	11	the	the	DET
fnp-3271	117	12	spinal	spinal	ADJ
fnp-3271	117	13	cord	cord	NOUN
fnp-3271	117	14	and	and	CCONJ
fnp-3271	117	15	even	even	ADV
fnp-3271	117	16	suggested	suggest	VERB
fnp-3271	117	17	that	that	SCONJ
fnp-3271	117	18	the	the	DET
fnp-3271	117	19	cerebrospinal	cerebrospinal	ADJ
fnp-3271	117	20	fluid	fluid	NOUN
fnp-3271	117	21	(	(	PUNCT
fnp-3271	117	22	csf	csf	NOUN
fnp-3271	117	23	)	)	PUNCT
fnp-3271	117	24	is	be	AUX
fnp-3271	117	25	primarily	primarily	ADV
fnp-3271	117	26	drained	drain	VERB
fnp-3271	117	27	via	via	ADP
fnp-3271	117	28	lymphatics	lymphatic	NOUN
fnp-3271	117	29	,	,	PUNCT
fnp-3271	117	30	rather	rather	ADV
fnp-3271	117	31	than	than	ADP
fnp-3271	117	32	into	into	ADP
fnp-3271	117	33	the	the	DET
fnp-3271	117	34	dural	dural	ADJ
fnp-3271	117	35	sinuses	sinus	NOUN
fnp-3271	118	1	[	[	X
fnp-3271	118	2	23	23	NUM
fnp-3271	118	3	]	]	PUNCT
fnp-3271	118	4	.	.	PUNCT
fnp-3271	119	1	in	in	ADP
fnp-3271	119	2	a	a	DET
fnp-3271	119	3	study	study	NOUN
fnp-3271	119	4	published	publish	VERB
fnp-3271	119	5	in	in	ADP
fnp-3271	119	6	nature	nature	NOUN
fnp-3271	119	7	,	,	PUNCT
fnp-3271	119	8	song	song	NOUN
fnp-3271	119	9	e	e	PROPN
fnp-3271	119	10	et	et	NOUN
fnp-3271	119	11	al	al	PROPN
fnp-3271	119	12	(	(	PUNCT
fnp-3271	119	13	last	last	ADJ
fnp-3271	119	14	authors	author	NOUN
fnp-3271	119	15	thomas	thomas	PROPN
fnp-3271	119	16	jl	jl	PROPN
fnp-3271	119	17	and	and	CCONJ
fnp-3271	119	18	iwasaki	iwasaki	PROPN
fnp-3271	119	19	a	a	PRON
fnp-3271	119	20	)	)	PUNCT
fnp-3271	119	21	report	report	NOUN
fnp-3271	119	22	that	that	SCONJ
fnp-3271	119	23	in	in	ADP
fnp-3271	119	24	mice	mouse	NOUN
fnp-3271	119	25	orthotopically	orthotopically	ADV
fnp-3271	119	26	injected	inject	VERB
fnp-3271	119	27	with	with	ADP
fnp-3271	119	28	glioblastoma	glioblastoma	NOUN
fnp-3271	119	29	cells	cell	NOUN
fnp-3271	119	30	,	,	PUNCT
fnp-3271	119	31	prophylactic	prophylactic	ADJ
fnp-3271	119	32	injection	injection	NOUN
fnp-3271	119	33	of	of	ADP
fnp-3271	119	34	the	the	DET
fnp-3271	119	35	lymphangiogenesis	lymphangiogenesis	NOUN
fnp-3271	119	36	-	-	PUNCT
fnp-3271	119	37	promoting	promote	VERB
fnp-3271	119	38	protein	protein	NOUN
fnp-3271	119	39	vegfc	vegfc	NOUN
fnp-3271	119	40	in	in	ADP
fnp-3271	119	41	the	the	DET
fnp-3271	119	42	csf	csf	NOUN
fnp-3271	119	43	resulted	result	VERB
fnp-3271	119	44	in	in	ADP
fnp-3271	119	45	enhanced	enhanced	ADJ
fnp-3271	119	46	priming	priming	NOUN
fnp-3271	119	47	of	of	ADP
fnp-3271	119	48	cd8	cd8	PROPN
fnp-3271	119	49	t	t	PROPN
fnp-3271	119	50	cells	cell	NOUN
fnp-3271	119	51	in	in	ADP
fnp-3271	119	52	the	the	DET
fnp-3271	119	53	draining	drain	VERB
fnp-3271	119	54	deep	deep	ADJ
fnp-3271	119	55	cervical	cervical	ADJ
fnp-3271	119	56	lymph	lymph	NOUN
fnp-3271	119	57	nodes	node	NOUN
fnp-3271	119	58	,	,	PUNCT
fnp-3271	119	59	migration	migration	NOUN
fnp-3271	119	60	of	of	ADP
fnp-3271	119	61	such	such	ADJ
fnp-3271	119	62	cells	cell	NOUN
fnp-3271	119	63	into	into	ADP
fnp-3271	119	64	the	the	DET
fnp-3271	119	65	tumor	tumor	NOUN
fnp-3271	119	66	,	,	PUNCT
fnp-3271	119	67	rapid	rapid	ADJ
fnp-3271	119	68	clearance	clearance	NOUN
fnp-3271	119	69	of	of	ADP
fnp-3271	119	70	the	the	DET
fnp-3271	119	71	glioblastoma	glioblastoma	NOUN
fnp-3271	119	72	and	and	CCONJ
fnp-3271	119	73	a	a	DET
fnp-3271	119	74	long	long	ADV
fnp-3271	119	75	-	-	PUNCT
fnp-3271	119	76	lasting	last	VERB
fnp-3271	119	77	anti	anti	ADJ
fnp-3271	119	78	-	-	ADJ
fnp-3271	119	79	tumor	tumor	ADJ
fnp-3271	119	80	memory	memory	NOUN
fnp-3271	119	81	response	response	NOUN
fnp-3271	119	82	[	[	X
fnp-3271	119	83	8	8	NUM
fnp-3271	119	84	]	]	PUNCT
fnp-3271	119	85	.	.	PUNCT
fnp-3271	120	1	transfection	transfection	NOUN
fnp-3271	120	2	of	of	ADP
fnp-3271	120	3	a	a	DET
fnp-3271	120	4	vegfc	vegfc	ADJ
fnp-3271	120	5	-	-	PUNCT
fnp-3271	120	6	expression	expression	NOUN
fnp-3271	120	7	mrna	mrna	PROPN
fnp-3271	120	8	construct	construct	NOUN
fnp-3271	120	9	was	be	AUX
fnp-3271	120	10	found	find	VERB
fnp-3271	120	11	to	to	PART
fnp-3271	120	12	work	work	VERB
fnp-3271	120	13	synergistically	synergistically	ADV
fnp-3271	120	14	with	with	ADP
fnp-3271	120	15	checkpoint	checkpoint	NOUN
fnp-3271	120	16	blockade	blockade	NOUN
fnp-3271	120	17	therapy	therapy	NOUN
fnp-3271	120	18	to	to	PART
fnp-3271	120	19	eradicate	eradicate	VERB
fnp-3271	120	20	existing	exist	VERB
fnp-3271	120	21	glioblastoma	glioblastoma	NOUN
fnp-3271	120	22	.	.	PUNCT
fnp-3271	121	1	furthermore	furthermore	ADV
fnp-3271	121	2	,	,	PUNCT
fnp-3271	121	3	hu	hu	PROPN
fnp-3271	121	4	x	x	PROPN
fnp-3271	121	5	,	,	PUNCT
fnp-3271	121	6	deng	deng	PROPN
fnp-3271	121	7	q	q	PROPN
fnp-3271	121	8	,	,	PUNCT
fnp-3271	121	9	ma	ma	PROPN
fnp-3271	121	10	l	l	PROPN
fnp-3271	121	11	,	,	PUNCT
fnp-3271	121	12	et	et	PROPN
fnp-3271	121	13	al	al	PROPN
fnp-3271	121	14	(	(	PUNCT
fnp-3271	121	15	last	last	ADJ
fnp-3271	121	16	author	author	NOUN
fnp-3271	121	17	luo	luo	PROPN
fnp-3271	121	18	j	j	PROPN
fnp-3271	121	19	)	)	PUNCT
fnp-3271	121	20	also	also	ADV
fnp-3271	121	21	published	publish	VERB
fnp-3271	121	22	a	a	DET
fnp-3271	121	23	study	study	NOUN
fnp-3271	121	24	last	last	ADJ
fnp-3271	121	25	year	year	NOUN
fnp-3271	121	26	on	on	ADP
fnp-3271	121	27	the	the	DET
fnp-3271	121	28	role	role	NOUN
fnp-3271	121	29	of	of	ADP
fnp-3271	121	30	meningeal	meningeal	ADJ
fnp-3271	121	31	lymphatic	lymphatic	ADJ
fnp-3271	121	32	vessels	vessel	NOUN
fnp-3271	121	33	in	in	ADP
fnp-3271	121	34	mice	mouse	NOUN
fnp-3271	121	35	with	with	ADP
fnp-3271	121	36	intracranial	intracranial	ADJ
fnp-3271	121	37	gliomas	glioma	NOUN
fnp-3271	121	38	or	or	CCONJ
fnp-3271	121	39	metastatic	metastatic	ADJ
fnp-3271	121	40	melanomas	melanoma	NOUN
fnp-3271	122	1	[	[	X
fnp-3271	122	2	9	9	NUM
fnp-3271	122	3	]	]	PUNCT
fnp-3271	122	4	.	.	PUNCT
fnp-3271	123	1	disruption	disruption	NOUN
fnp-3271	123	2	of	of	ADP
fnp-3271	123	3	dorsal	dorsal	ADJ
fnp-3271	123	4	meningeal	meningeal	NOUN
fnp-3271	123	5	lymphatics	lymphatic	NOUN
fnp-3271	123	6	alone	alone	ADV
fnp-3271	123	7	impaired	impair	VERB
fnp-3271	123	8	the	the	DET
fnp-3271	123	9	dissemination	dissemination	NOUN
fnp-3271	123	10	of	of	ADP
fnp-3271	123	11	tumor	tumor	NOUN
fnp-3271	123	12	cells	cell	NOUN
fnp-3271	123	13	and	and	CCONJ
fnp-3271	123	14	dendritic	dendritic	ADJ
fnp-3271	123	15	cells	cell	NOUN
fnp-3271	123	16	from	from	ADP
fnp-3271	123	17	the	the	DET
fnp-3271	123	18	brain	brain	NOUN
fnp-3271	123	19	tumors	tumor	NOUN
fnp-3271	123	20	to	to	ADP
fnp-3271	123	21	deep	deep	ADJ
fnp-3271	123	22	cervical	cervical	ADJ
fnp-3271	123	23	lymph	lymph	NOUN
fnp-3271	123	24	nodes	node	NOUN
fnp-3271	123	25	,	,	PUNCT
fnp-3271	123	26	while	while	SCONJ
fnp-3271	123	27	such	such	ADJ
fnp-3271	123	28	trafficking	trafficking	NOUN
fnp-3271	123	29	of	of	ADP
fnp-3271	123	30	dendritic	dendritic	ADJ
fnp-3271	123	31	cells	cell	NOUN
fnp-3271	123	32	was	be	AUX
fnp-3271	123	33	found	find	VERB
fnp-3271	123	34	to	to	PART
fnp-3271	123	35	be	be	AUX
fnp-3271	123	36	increased	increase	VERB
fnp-3271	123	37	in	in	ADP
fnp-3271	123	38	mice	mouse	NOUN
fnp-3271	123	39	with	with	ADP
fnp-3271	123	40	enhanced	enhanced	ADJ
fnp-3271	123	41	dorsal	dorsal	NOUN
fnp-3271	123	42	meningeal	meningeal	NOUN
fnp-3271	123	43	lymphangiogenesis	lymphangiogenesis	NOUN
fnp-3271	123	44	.	.	PUNCT
fnp-3271	124	1	also	also	ADV
fnp-3271	124	2	,	,	PUNCT
fnp-3271	124	3	disruption	disruption	NOUN
fnp-3271	124	4	of	of	ADP
fnp-3271	124	5	dorsal	dorsal	ADJ
fnp-3271	124	6	meningeal	meningeal	NOUN
fnp-3271	124	7	lymphatics	lymphatic	NOUN
fnp-3271	124	8	alone	alone	ADV
fnp-3271	124	9	(	(	PUNCT
fnp-3271	124	10	without	without	ADP
fnp-3271	124	11	affecting	affect	VERB
fnp-3271	124	12	basal	basal	NOUN
fnp-3271	124	13	or	or	CCONJ
fnp-3271	124	14	nasal	nasal	ADJ
fnp-3271	124	15	meningeal	meningeal	ADJ
fnp-3271	124	16	lymphatics	lymphatic	NOUN
fnp-3271	124	17	)	)	PUNCT
fnp-3271	124	18	significantly	significantly	ADV
fnp-3271	124	19	reduced	reduce	VERB
fnp-3271	124	20	the	the	DET
fnp-3271	124	21	efficacy	efficacy	NOUN
fnp-3271	124	22	of	of	ADP
fnp-3271	124	23	combined	combined	ADJ
fnp-3271	124	24	anti	anti	ADJ
fnp-3271	124	25	-	-	ADJ
fnp-3271	124	26	pd-1	pd-1	ADJ
fnp-3271	124	27	/	/	SYM
fnp-3271	124	28	ctla-4	ctla-4	NOUN
fnp-3271	124	29	checkpoint	checkpoint	NOUN
fnp-3271	124	30	therapy	therapy	NOUN
fnp-3271	124	31	in	in	ADP
fnp-3271	124	32	striatal	striatal	ADJ
fnp-3271	124	33	tumor	tumor	NOUN
fnp-3271	124	34	models	model	NOUN
fnp-3271	124	35	,	,	PUNCT
fnp-3271	124	36	while	while	SCONJ
fnp-3271	124	37	tumors	tumor	NOUN
fnp-3271	124	38	overexpressing	overexpresse	VERB
fnp-3271	124	39	vegfc	vegfc	NOUN
fnp-3271	124	40	displayed	display	VERB
fnp-3271	124	41	a	a	DET
fnp-3271	124	42	better	well	ADJ
fnp-3271	124	43	response	response	NOUN
fnp-3271	124	44	to	to	ADP
fnp-3271	124	45	such	such	ADJ
fnp-3271	124	46	combination	combination	NOUN
fnp-3271	124	47	therapy	therapy	NOUN
fnp-3271	124	48	.	.	PUNCT
fnp-3271	125	1	these	these	DET
fnp-3271	125	2	studies	study	NOUN
fnp-3271	125	3	suggest	suggest	VERB
fnp-3271	125	4	that	that	SCONJ
fnp-3271	125	5	the	the	DET
fnp-3271	125	6	immunosurveillance	immunosurveillance	NOUN
fnp-3271	125	7	-	-	PUNCT
fnp-3271	125	8	promoting	promote	VERB
fnp-3271	125	9	capacity	capacity	NOUN
fnp-3271	125	10	of	of	ADP
fnp-3271	125	11	vegfc	vegfc	NOUN
fnp-3271	125	12	may	may	AUX
fnp-3271	125	13	be	be	AUX
fnp-3271	125	14	exploited	exploit	VERB
fnp-3271	125	15	to	to	PART
fnp-3271	125	16	increase	increase	VERB
fnp-3271	125	17	the	the	DET
fnp-3271	125	18	efficacy	efficacy	NOUN
fnp-3271	125	19	of	of	ADP
fnp-3271	125	20	immunotherapeutic	immunotherapeutic	ADJ
fnp-3271	125	21	approaches	approach	NOUN
fnp-3271	125	22	for	for	ADP
fnp-3271	125	23	brain	brain	NOUN
fnp-3271	125	24	tumors	tumor	NOUN
fnp-3271	125	25	.	.	PUNCT
fnp-3271	126	1	topic	topic	NOUN
fnp-3271	126	2	7	7	NUM
fnp-3271	126	3	.	.	PUNCT
fnp-3271	126	4	impact	impact	NOUN
fnp-3271	126	5	of	of	ADP
fnp-3271	126	6	tumor	tumor	NOUN
fnp-3271	126	7	microenvironment	microenvironment	NOUN
fnp-3271	126	8	on	on	ADP
fnp-3271	126	9	preclinical	preclinical	ADJ
fnp-3271	126	10	glioblastoma	glioblastoma	NOUN
fnp-3271	126	11	models	model	NOUN
fnp-3271	126	12	[	[	X
fnp-3271	126	13	10	10	NUM
fnp-3271	126	14	]	]	X
fnp-3271	126	15	a	a	DET
fnp-3271	126	16	wide	wide	ADJ
fnp-3271	126	17	variety	variety	NOUN
fnp-3271	126	18	of	of	ADP
fnp-3271	126	19	preclinical	preclinical	ADJ
fnp-3271	126	20	models	model	NOUN
fnp-3271	126	21	for	for	ADP
fnp-3271	126	22	human	human	ADJ
fnp-3271	126	23	glioblastomas	glioblastoma	NOUN
fnp-3271	126	24	serve	serve	VERB
fnp-3271	126	25	as	as	ADP
fnp-3271	126	26	an	an	DET
fnp-3271	126	27	important	important	ADJ
fnp-3271	126	28	tool	tool	NOUN
fnp-3271	126	29	for	for	ADP
fnp-3271	126	30	studying	study	VERB
fnp-3271	126	31	these	these	DET
fnp-3271	126	32	brain	brain	NOUN
fnp-3271	126	33	tumors	tumor	NOUN
fnp-3271	126	34	.	.	PUNCT
fnp-3271	127	1	however	however	ADV
fnp-3271	127	2	,	,	PUNCT
fnp-3271	127	3	no	no	DET
fnp-3271	127	4	model	model	NOUN
fnp-3271	127	5	is	be	AUX
fnp-3271	127	6	perfect	perfect	ADJ
fnp-3271	127	7	,	,	PUNCT
fnp-3271	127	8	and	and	CCONJ
fnp-3271	127	9	it	it	PRON
fnp-3271	127	10	is	be	AUX
fnp-3271	127	11	important	important	ADJ
fnp-3271	127	12	to	to	PART
fnp-3271	127	13	determine	determine	VERB
fnp-3271	127	14	if	if	SCONJ
fnp-3271	127	15	/	/	SYM
fnp-3271	127	16	how	how	SCONJ
fnp-3271	127	17	different	different	ADJ
fnp-3271	127	18	models	model	NOUN
fnp-3271	127	19	recapitulate	recapitulate	VERB
fnp-3271	127	20	different	different	ADJ
fnp-3271	127	21	aspects	aspect	NOUN
fnp-3271	127	22	of	of	ADP
fnp-3271	127	23	human	human	ADJ
fnp-3271	127	24	glioblastomas	glioblastoma	NOUN
fnp-3271	127	25	.	.	PUNCT
fnp-3271	128	1	to	to	PART
fnp-3271	128	2	address	address	VERB
fnp-3271	128	3	this	this	DET
fnp-3271	128	4	issue	issue	NOUN
fnp-3271	128	5	,	,	PUNCT
fnp-3271	128	6	pine	pine	PROPN
fnp-3271	128	7	ar	ar	PROPN
fnp-3271	128	8	,	,	PUNCT
fnp-3271	128	9	cirigliano	cirigliano	VERB
fnp-3271	128	10	sm	sm	PROPN
fnp-3271	128	11	,	,	PUNCT
fnp-3271	128	12	et	et	PROPN
fnp-3271	128	13	al	al	PROPN
fnp-3271	128	14	(	(	PUNCT
fnp-3271	128	15	last	last	ADJ
fnp-3271	128	16	author	author	NOUN
fnp-3271	128	17	fine	fine	PROPN
fnp-3271	128	18	ha	ha	INTJ
fnp-3271	128	19	)	)	PUNCT
fnp-3271	128	20	performed	perform	VERB
fnp-3271	128	21	a	a	DET
fnp-3271	128	22	complete	complete	ADJ
fnp-3271	128	23	transcriptomic	transcriptomic	ADJ
fnp-3271	128	24	characterization	characterization	NOUN
fnp-3271	128	25	of	of	ADP
fnp-3271	128	26	tumor	tumor	NOUN
fnp-3271	128	27	cells	cell	NOUN
fnp-3271	128	28	from	from	ADP
fnp-3271	128	29	5	5	NUM
fnp-3271	128	30	patients	patient	NOUN
fnp-3271	128	31	across	across	ADP
fnp-3271	128	32	four	four	NUM
fnp-3271	128	33	patient	patient	NOUN
fnp-3271	128	34	-	-	PUNCT
fnp-3271	128	35	specific	specific	ADJ
fnp-3271	128	36	glioblastoma	glioblastoma	NOUN
fnp-3271	128	37	–	–	PUNCT
fnp-3271	128	38	derived	derive	VERB
fnp-3271	128	39	model	model	NOUN
fnp-3271	128	40	types	type	NOUN
fnp-3271	128	41	:	:	PUNCT
fnp-3271	128	42	1	1	X
fnp-3271	128	43	)	)	PUNCT
fnp-3271	128	44	glioma	glioma	NOUN
fnp-3271	128	45	spheres	sphere	NOUN
fnp-3271	128	46	(	(	PUNCT
fnp-3271	128	47	gss	gss	PROPN
fnp-3271	128	48	)	)	PUNCT
fnp-3271	128	49	,	,	PUNCT
fnp-3271	128	50	2	2	X
fnp-3271	128	51	)	)	PUNCT
fnp-3271	128	52	tumor	tumor	NOUN
fnp-3271	128	53	organoids	organoid	NOUN
fnp-3271	128	54	(	(	PUNCT
fnp-3271	128	55	tos	tos	NOUN
fnp-3271	128	56	)	)	PUNCT
fnp-3271	128	57	,	,	PUNCT
fnp-3271	128	58	3	3	X
fnp-3271	128	59	)	)	PUNCT
fnp-3271	128	60	glioblastoma	glioblastoma	NOUN
fnp-3271	128	61	cerebral	cerebral	ADJ
fnp-3271	128	62	organoids	organoid	NOUN
fnp-3271	128	63	(	(	PUNCT
fnp-3271	128	64	glicos	glicos	NOUN
fnp-3271	128	65	)	)	PUNCT
fnp-3271	128	66	,	,	PUNCT
fnp-3271	128	67	and	and	CCONJ
fnp-3271	128	68	4	4	X
fnp-3271	128	69	)	)	PUNCT
fnp-3271	128	70	patient	patient	NOUN
fnp-3271	128	71	-	-	PUNCT
fnp-3271	128	72	derived	derive	VERB
fnp-3271	128	73	xenografts	xenograft	NOUN
fnp-3271	128	74	(	(	PUNCT
fnp-3271	128	75	pdxs	pdxs	PROPN
fnp-3271	128	76	)	)	PUNCT
fnp-3271	128	77	.	.	PUNCT
fnp-3271	129	1	they	they	PRON
fnp-3271	129	2	found	find	VERB
fnp-3271	129	3	that	that	SCONJ
fnp-3271	129	4	glicos	glico	NOUN
fnp-3271	129	5	and	and	CCONJ
fnp-3271	129	6	pdxs	pdxs	PROPN
fnp-3271	129	7	more	more	ADV
fnp-3271	129	8	closely	closely	ADV
fnp-3271	129	9	recapitulated	recapitulate	VERB
fnp-3271	129	10	the	the	DET
fnp-3271	129	11	invasive	invasive	ADJ
fnp-3271	129	12	growth	growth	NOUN
fnp-3271	129	13	of	of	ADP
fnp-3271	129	14	human	human	ADJ
fnp-3271	129	15	glioblastomas	glioblastoma	NOUN
fnp-3271	129	16	.	.	PUNCT
fnp-3271	130	1	also	also	ADV
fnp-3271	130	2	,	,	PUNCT
fnp-3271	130	3	the	the	DET
fnp-3271	130	4	results	result	NOUN
fnp-3271	130	5	obtained	obtain	VERB
fnp-3271	130	6	with	with	ADP
fnp-3271	130	7	bulk	bulk	ADJ
fnp-3271	130	8	and	and	CCONJ
fnp-3271	130	9	single	single	ADJ
fnp-3271	130	10	cell	cell	NOUN
fnp-3271	130	11	rna	rna	NOUN
fnp-3271	130	12	sequencing	sequence	VERB
fnp-3271	130	13	analysis	analysis	NOUN
fnp-3271	130	14	of	of	ADP
fnp-3271	130	15	these	these	DET
fnp-3271	130	16	models	model	NOUN
fnp-3271	130	17	more	more	ADV
fnp-3271	130	18	closely	closely	ADV
fnp-3271	130	19	resembled	resemble	VERB
fnp-3271	130	20	the	the	DET
fnp-3271	130	21	human	human	ADJ
fnp-3271	130	22	tumors	tumor	NOUN
fnp-3271	130	23	.	.	PUNCT
fnp-3271	131	1	compared	compare	VERB
fnp-3271	131	2	to	to	ADP
fnp-3271	131	3	the	the	DET
fnp-3271	131	4	other	other	ADJ
fnp-3271	131	5	models	model	NOUN
fnp-3271	131	6	,	,	PUNCT
fnp-3271	131	7	glicos	glico	NOUN
fnp-3271	131	8	were	be	AUX
fnp-3271	131	9	enriched	enrich	VERB
fnp-3271	131	10	for	for	ADP
fnp-3271	131	11	a	a	DET
fnp-3271	131	12	neural	neural	ADJ
fnp-3271	131	13	progenitor	progenitor	NOUN
fnp-3271	131	14	-	-	PUNCT
fnp-3271	131	15	like	like	ADJ
fnp-3271	131	16	cell	cell	NOUN
fnp-3271	131	17	subpopulation	subpopulation	NOUN
fnp-3271	131	18	,	,	PUNCT
fnp-3271	131	19	showed	show	VERB
fnp-3271	131	20	lower	low	ADJ
fnp-3271	131	21	percentages	percentage	NOUN
fnp-3271	131	22	of	of	ADP
fnp-3271	131	23	mesenchymal	mesenchymal	NOUN
fnp-3271	131	24	cells	cell	NOUN
fnp-3271	131	25	,	,	PUNCT
fnp-3271	131	26	showed	show	VERB
fnp-3271	131	27	retention	retention	NOUN
fnp-3271	131	28	of	of	ADP
fnp-3271	131	29	neural	neural	ADJ
fnp-3271	131	30	and	and	CCONJ
fnp-3271	131	31	oligodendrocyte	oligodendrocyte	ADJ
fnp-3271	131	32	progenitor	progenitor	NOUN
fnp-3271	131	33	cell	cell	NOUN
fnp-3271	131	34	populations	population	NOUN
fnp-3271	131	35	and	and	CCONJ
fnp-3271	131	36	recapitulated	recapitulate	VERB
fnp-3271	131	37	the	the	DET
fnp-3271	131	38	cellular	cellular	ADJ
fnp-3271	131	39	states	state	NOUN
fnp-3271	131	40	and	and	CCONJ
fnp-3271	131	41	their	their	PRON
fnp-3271	131	42	plasticity	plasticity	NOUN
fnp-3271	131	43	found	find	VERB
fnp-3271	131	44	in	in	ADP
fnp-3271	131	45	the	the	DET
fnp-3271	131	46	corresponding	corresponding	ADJ
fnp-3271	131	47	human	human	ADJ
fnp-3271	131	48	tumors	tumor	NOUN
fnp-3271	131	49	best	well	ADV
fnp-3271	131	50	.	.	PUNCT
fnp-3271	132	1	although	although	SCONJ
fnp-3271	132	2	glicos	glico	NOUN
fnp-3271	132	3	thus	thus	ADV
fnp-3271	132	4	had	have	VERB
fnp-3271	132	5	a	a	DET
fnp-3271	132	6	profile	profile	NOUN
fnp-3271	132	7	most	most	ADV
fnp-3271	132	8	similar	similar	ADJ
fnp-3271	132	9	to	to	ADP
fnp-3271	132	10	that	that	PRON
fnp-3271	132	11	of	of	ADP
fnp-3271	132	12	the	the	DET
fnp-3271	132	13	parental	parental	ADJ
fnp-3271	132	14	glioblastomas	glioblastoma	NOUN
fnp-3271	132	15	,	,	PUNCT
fnp-3271	132	16	the	the	DET
fnp-3271	132	17	similarity	similarity	NOUN
fnp-3271	132	18	between	between	ADP
fnp-3271	132	19	glicos	glico	NOUN
fnp-3271	132	20	and	and	CCONJ
fnp-3271	132	21	the	the	DET
fnp-3271	132	22	original	original	ADJ
fnp-3271	132	23	glioblastomas	glioblastoma	NOUN
fnp-3271	132	24	was	be	AUX
fnp-3271	132	25	reduced	reduce	VERB
fnp-3271	132	26	when	when	SCONJ
fnp-3271	132	27	glico	glico	NOUN
fnp-3271	132	28	cells	cell	NOUN
fnp-3271	132	29	were	be	AUX
fnp-3271	132	30	replated	replate	VERB
fnp-3271	132	31	in	in	ADP
fnp-3271	132	32	two	two	NUM
fnp-3271	132	33	-	-	PUNCT
fnp-3271	132	34	dimensional	dimensional	ADJ
fnp-3271	132	35	culture	culture	NOUN
fnp-3271	132	36	conditions	condition	NOUN
fnp-3271	132	37	.	.	PUNCT
fnp-3271	133	1	this	this	DET
fnp-3271	133	2	work	work	NOUN
fnp-3271	133	3	underscores	underscore	VERB
fnp-3271	133	4	the	the	DET
fnp-3271	133	5	critical	critical	ADJ
fnp-3271	133	6	impact	impact	NOUN
fnp-3271	133	7	of	of	ADP
fnp-3271	133	8	the	the	DET
fnp-3271	133	9	microenvironment	microenvironment	NOUN
fnp-3271	133	10	in	in	ADP
fnp-3271	133	11	glioblastoma	glioblastoma	NOUN
fnp-3271	133	12	models	model	NOUN
fnp-3271	133	13	on	on	ADP
fnp-3271	133	14	the	the	DET
fnp-3271	133	15	degree	degree	NOUN
fnp-3271	133	16	to	to	PART
fnp-3271	133	17	which	which	PRON
fnp-3271	133	18	cellular	cellular	ADJ
fnp-3271	133	19	states	state	NOUN
fnp-3271	133	20	,	,	PUNCT
fnp-3271	133	21	as	as	SCONJ
fnp-3271	133	22	found	find	VERB
fnp-3271	133	23	in	in	ADP
fnp-3271	133	24	human	human	ADJ
fnp-3271	133	25	glioblastomas	glioblastoma	NOUN
fnp-3271	133	26	,	,	PUNCT
fnp-3271	133	27	are	be	AUX
fnp-3271	133	28	recapitulated	recapitulate	VERB
fnp-3271	133	29	.	.	PUNCT
fnp-3271	134	1	thereby	thereby	ADV
fnp-3271	134	2	,	,	PUNCT
fnp-3271	134	3	this	this	DET
fnp-3271	134	4	study	study	NOUN
fnp-3271	134	5	serves	serve	VERB
fnp-3271	134	6	as	as	ADP
fnp-3271	134	7	a	a	DET
fnp-3271	134	8	kind	kind	NOUN
fnp-3271	134	9	of	of	ADP
fnp-3271	134	10	reality	reality	NOUN
fnp-3271	134	11	check	check	NOUN
fnp-3271	134	12	for	for	ADP
fnp-3271	134	13	those	those	PRON
fnp-3271	134	14	who	who	PRON
fnp-3271	134	15	exploit	exploit	VERB
fnp-3271	134	16	such	such	ADJ
fnp-3271	134	17	preclinical	preclinical	ADJ
fnp-3271	134	18	models	model	NOUN
fnp-3271	134	19	for	for	ADP
fnp-3271	134	20	elucidation	elucidation	NOUN
fnp-3271	134	21	of	of	ADP
fnp-3271	134	22	the	the	DET
fnp-3271	134	23	pathobiology	pathobiology	NOUN
fnp-3271	134	24	of	of	ADP
fnp-3271	134	25	and	and	CCONJ
fnp-3271	134	26	identification	identification	NOUN
fnp-3271	134	27	of	of	ADP
fnp-3271	134	28	therapeutic	therapeutic	ADJ
fnp-3271	134	29	approaches	approach	NOUN
fnp-3271	134	30	for	for	ADP
fnp-3271	134	31	glioblastomas	glioblastoma	NOUN
fnp-3271	134	32	in	in	ADP
fnp-3271	134	33	clinical	clinical	ADJ
fnp-3271	134	34	practice	practice	NOUN
fnp-3271	134	35	.	.	PUNCT
fnp-3271	135	1	topic	topic	NOUN
fnp-3271	135	2	8	8	NUM
fnp-3271	135	3	.	.	PUNCT
fnp-3271	135	4	newly	newly	ADV
fnp-3271	135	5	discovered	discover	VERB
fnp-3271	135	6	medulloblastoma	medulloblastoma	ADJ
fnp-3271	135	7	predisposition	predisposition	NOUN
fnp-3271	135	8	syndromes	syndrome	NOUN
fnp-3271	135	9	[	[	X
fnp-3271	135	10	11	11	NUM
fnp-3271	135	11	,	,	PUNCT
fnp-3271	135	12	12	12	NUM
fnp-3271	135	13	]	]	X
fnp-3271	135	14	medulloblastomas	medulloblastoma	NOUN
fnp-3271	135	15	are	be	AUX
fnp-3271	135	16	by	by	ADP
fnp-3271	135	17	far	far	ADV
fnp-3271	135	18	the	the	DET
fnp-3271	135	19	most	most	ADV
fnp-3271	135	20	frequent	frequent	ADJ
fnp-3271	135	21	of	of	ADP
fnp-3271	135	22	the	the	DET
fnp-3271	135	23	embryonal	embryonal	ADJ
fnp-3271	135	24	cns	cns	NOUN
fnp-3271	135	25	tumors	tumor	NOUN
fnp-3271	135	26	,	,	PUNCT
fnp-3271	135	27	most	most	ADV
fnp-3271	135	28	commonly	commonly	ADV
fnp-3271	135	29	present	present	ADJ
fnp-3271	135	30	in	in	ADP
fnp-3271	135	31	childhood	childhood	NOUN
fnp-3271	135	32	and	and	CCONJ
fnp-3271	135	33	display	display	VERB
fnp-3271	135	34	considerable	considerable	ADJ
fnp-3271	135	35	biological	biological	ADJ
fnp-3271	135	36	heterogeneity	heterogeneity	NOUN
fnp-3271	135	37	,	,	PUNCT
fnp-3271	135	38	with	with	ADP
fnp-3271	135	39	distinct	distinct	ADJ
fnp-3271	135	40	molecularly	molecularly	ADV
fnp-3271	135	41	defined	define	VERB
fnp-3271	135	42	groups	group	NOUN
fnp-3271	135	43	listed	list	VERB
fnp-3271	135	44	in	in	ADP
fnp-3271	135	45	the	the	DET
fnp-3271	135	46	who	who	PRON
fnp-3271	135	47	classification	classification	VERB
fnp-3271	135	48	.	.	PUNCT
fnp-3271	136	1	a	a	DET
fnp-3271	136	2	recent	recent	ADJ
fnp-3271	136	3	review	review	NOUN
fnp-3271	136	4	reports	report	VERB
fnp-3271	136	5	that	that	SCONJ
fnp-3271	136	6	pathogenic	pathogenic	ADJ
fnp-3271	136	7	germline	germline	NOUN
fnp-3271	136	8	variants	variant	NOUN
fnp-3271	136	9	in	in	ADP
fnp-3271	136	10	established	establish	VERB
fnp-3271	136	11	cancer	cancer	NOUN
fnp-3271	136	12	predisposition	predisposition	NOUN
fnp-3271	136	13	genes	gene	NOUN
fnp-3271	136	14	can	can	AUX
fnp-3271	136	15	be	be	AUX
fnp-3271	136	16	identified	identify	VERB
fnp-3271	136	17	in	in	ADP
fnp-3271	136	18	about	about	ADV
fnp-3271	136	19	5	5	NUM
fnp-3271	136	20	%	%	NOUN
fnp-3271	136	21	of	of	ADP
fnp-3271	136	22	patients	patient	NOUN
fnp-3271	136	23	with	with	ADP
fnp-3271	136	24	medulloblastoma	medulloblastoma	NOUN
fnp-3271	136	25	[	[	X
fnp-3271	136	26	24	24	NUM
fnp-3271	136	27	]	]	PUNCT
fnp-3271	136	28	.	.	PUNCT
fnp-3271	137	1	this	this	PRON
fnp-3271	137	2	includes	include	VERB
fnp-3271	137	3	syndromes	syndrome	NOUN
fnp-3271	137	4	with	with	ADP
fnp-3271	137	5	a	a	DET
fnp-3271	137	6	germline	germline	NOUN
fnp-3271	137	7	defect	defect	NOUN
fnp-3271	137	8	in	in	ADP
fnp-3271	137	9	sufu	sufu	NOUN
fnp-3271	137	10	or	or	CCONJ
fnp-3271	137	11	ptch1	ptch1	PROPN
fnp-3271	137	12	(	(	PUNCT
fnp-3271	137	13	nevoid	nevoid	PROPN
fnp-3271	137	14	basal	basal	PROPN
fnp-3271	137	15	cell	cell	NOUN
fnp-3271	137	16	carcinoma	carcinoma	NOUN
fnp-3271	137	17	syndrome	syndrome	NOUN
fnp-3271	137	18	/	/	SYM
fnp-3271	137	19	gorlin	gorlin	PROPN
fnp-3271	137	20	syndrome	syndrome	PROPN
fnp-3271	137	21	)	)	PUNCT
fnp-3271	137	22	,	,	PUNCT
fnp-3271	137	23	tp53	tp53	PROPN
fnp-3271	137	24	(	(	PUNCT
fnp-3271	137	25	li	li	PROPN
fnp-3271	137	26	–	–	PUNCT
fnp-3271	137	27	fraumeni	fraumeni	ADJ
fnp-3271	137	28	syndrome	syndrome	NOUN
fnp-3271	137	29	)	)	PUNCT
fnp-3271	137	30	,	,	PUNCT
fnp-3271	137	31	apc	apc	PROPN
fnp-3271	137	32	(	(	PUNCT
fnp-3271	137	33	familial	familial	ADJ
fnp-3271	137	34	adenomatous	adenomatous	ADJ
fnp-3271	137	35	polyposis	polyposis	NOUN
fnp-3271	137	36	)	)	PUNCT
fnp-3271	137	37	,	,	PUNCT
fnp-3271	137	38	crebbp	crebbp	NOUN
fnp-3271	137	39	(	(	PUNCT
fnp-3271	137	40	rubinstein	rubinstein	PROPN
fnp-3271	137	41	–	–	PUNCT
fnp-3271	137	42	taybi	taybi	NOUN
fnp-3271	137	43	syndrome	syndrome	NOUN
fnp-3271	137	44	)	)	PUNCT
fnp-3271	137	45	,	,	PUNCT
fnp-3271	137	46	nbs1	nbs1	NOUN
fnp-3271	137	47	(	(	PUNCT
fnp-3271	137	48	nijmegen	nijmegen	NOUN
fnp-3271	137	49	breakage	breakage	NOUN
fnp-3271	137	50	syndrome	syndrome	NOUN
fnp-3271	137	51	)	)	PUNCT
fnp-3271	137	52	,	,	PUNCT
fnp-3271	137	53	palb2	palb2	NOUN
fnp-3271	137	54	,	,	PUNCT
fnp-3271	137	55	and	and	CCONJ
fnp-3271	137	56	brca2	brca2	PROPN
fnp-3271	137	57	.	.	PUNCT
fnp-3271	138	1	in	in	ADP
fnp-3271	138	2	2020	2020	NUM
fnp-3271	138	3	,	,	PUNCT
fnp-3271	138	4	two	two	NUM
fnp-3271	138	5	additional	additional	ADJ
fnp-3271	138	6	germline	germline	NOUN
fnp-3271	138	7	mutations	mutation	NOUN
fnp-3271	138	8	were	be	AUX
fnp-3271	138	9	reported	report	VERB
fnp-3271	138	10	that	that	SCONJ
fnp-3271	138	11	predispose	predispose	VERB
fnp-3271	138	12	to	to	ADP
fnp-3271	138	13	pediatric	pediatric	ADJ
fnp-3271	138	14	medulloblastoma	medulloblastoma	NOUN
fnp-3271	138	15	.	.	PUNCT
fnp-3271	139	1	waszak	waszak	PROPN
fnp-3271	139	2	sm	sm	PROPN
fnp-3271	139	3	,	,	PUNCT
fnp-3271	139	4	robinson	robinson	PROPN
fnp-3271	139	5	gw	gw	PROPN
fnp-3271	139	6	,	,	PUNCT
fnp-3271	139	7	et	et	PROPN
fnp-3271	139	8	al	al	PROPN
fnp-3271	139	9	(	(	PUNCT
fnp-3271	139	10	last	last	ADJ
fnp-3271	139	11	authors	author	NOUN
fnp-3271	139	12	korbel	korbel	PROPN
fnp-3271	139	13	jo	jo	PROPN
fnp-3271	139	14	,	,	PUNCT
fnp-3271	139	15	northcott	northcott	PROPN
fnp-3271	139	16	pa	pa	PROPN
fnp-3271	139	17	and	and	CCONJ
fnp-3271	139	18	pfister	pfister	PROPN
fnp-3271	139	19	sm	sm	PROPN
fnp-3271	139	20	)	)	PUNCT
fnp-3271	139	21	published	publish	VERB
fnp-3271	139	22	a	a	DET
fnp-3271	139	23	study	study	NOUN
fnp-3271	139	24	in	in	ADP
fnp-3271	139	25	nature	nature	NOUN
fnp-3271	139	26	of	of	ADP
fnp-3271	139	27	1022	1022	NUM
fnp-3271	139	28	patients	patient	NOUN
fnp-3271	139	29	with	with	ADP
fnp-3271	139	30	medulloblastoma	medulloblastoma	NOUN
fnp-3271	139	31	from	from	ADP
fnp-3271	139	32	whom	whom	PRON
fnp-3271	139	33	blood	blood	NOUN
fnp-3271	139	34	samples	sample	NOUN
fnp-3271	139	35	and	and	CCONJ
fnp-3271	139	36	tumor	tumor	NOUN
fnp-3271	139	37	samples	sample	NOUN
fnp-3271	139	38	were	be	AUX
fnp-3271	139	39	analyzed	analyze	VERB
fnp-3271	139	40	for	for	ADP
fnp-3271	139	41	germline	germline	NOUN
fnp-3271	139	42	mutations	mutation	NOUN
fnp-3271	139	43	in	in	ADP
fnp-3271	139	44	110	110	NUM
fnp-3271	139	45	cancer	cancer	NOUN
fnp-3271	139	46	predisposition	predisposition	NOUN
fnp-3271	139	47	genes	gene	NOUN
fnp-3271	139	48	[	[	X
fnp-3271	139	49	11	11	NUM
fnp-3271	139	50	]	]	PUNCT
fnp-3271	139	51	.	.	PUNCT
fnp-3271	140	1	they	they	PRON
fnp-3271	140	2	identified	identify	VERB
fnp-3271	140	3	rare	rare	ADJ
fnp-3271	140	4	germline	germline	NOUN
fnp-3271	140	5	loss	loss	NOUN
fnp-3271	140	6	-	-	PUNCT
fnp-3271	140	7	of	of	ADP
fnp-3271	140	8	-	-	PUNCT
fnp-3271	140	9	function	function	NOUN
fnp-3271	140	10	variants	variant	NOUN
fnp-3271	140	11	across	across	ADP
fnp-3271	140	12	the	the	DET
fnp-3271	140	13	elongator	elongator	NOUN
fnp-3271	140	14	complex	complex	ADJ
fnp-3271	140	15	protein	protein	NOUN
fnp-3271	140	16	1	1	NUM
fnp-3271	140	17	(	(	PUNCT
fnp-3271	140	18	elp1	elp1	PROPN
fnp-3271	140	19	)	)	PUNCT
fnp-3271	140	20	gene	gene	NOUN
fnp-3271	140	21	in	in	ADP
fnp-3271	140	22	14	14	NUM
fnp-3271	140	23	%	%	NOUN
fnp-3271	140	24	of	of	ADP
fnp-3271	140	25	pediatric	pediatric	ADJ
fnp-3271	140	26	patients	patient	NOUN
fnp-3271	140	27	with	with	ADP
fnp-3271	140	28	the	the	DET
fnp-3271	140	29	sonic	sonic	ADJ
fnp-3271	140	30	hedgehog	hedgehog	PROPN
fnp-3271	140	31	medulloblastoma	medulloblastoma	PROPN
fnp-3271	140	32	subgroup	subgroup	NOUN
fnp-3271	140	33	(	(	PUNCT
fnp-3271	140	34	mbshh	mbshh	PROPN
fnp-3271	140	35	)	)	PUNCT
fnp-3271	140	36	.	.	PUNCT
fnp-3271	141	1	elp1	elp1	PROPN
fnp-3271	141	2	was	be	AUX
fnp-3271	141	3	the	the	DET
fnp-3271	141	4	most	most	ADV
fnp-3271	141	5	common	common	ADJ
fnp-3271	141	6	medulloblastoma	medulloblastoma	NOUN
fnp-3271	141	7	predisposition	predisposition	NOUN
fnp-3271	141	8	gene	gene	NOUN
fnp-3271	141	9	and	and	CCONJ
fnp-3271	141	10	increased	increase	VERB
fnp-3271	141	11	the	the	DET
fnp-3271	141	12	prevalence	prevalence	NOUN
fnp-3271	141	13	of	of	ADP
fnp-3271	141	14	genetic	genetic	ADJ
fnp-3271	141	15	predisposition	predisposition	NOUN
fnp-3271	141	16	to	to	ADP
fnp-3271	141	17	40	40	NUM
fnp-3271	141	18	%	%	NOUN
fnp-3271	141	19	among	among	ADP
fnp-3271	141	20	pediatric	pediatric	ADJ
fnp-3271	141	21	patients	patient	NOUN
fnp-3271	141	22	in	in	ADP
fnp-3271	141	23	this	this	DET
fnp-3271	141	24	mbshh	mbshh	NOUN
fnp-3271	141	25	subgroup	subgroup	NOUN
fnp-3271	141	26	.	.	PUNCT
fnp-3271	142	1	parent	parent	NOUN
fnp-3271	142	2	-	-	PUNCT
fnp-3271	142	3	offspring	offspring	NOUN
fnp-3271	142	4	and	and	CCONJ
fnp-3271	142	5	pedigree	pedigree	ADJ
fnp-3271	142	6	analyses	analysis	NOUN
fnp-3271	142	7	identified	identify	VERB
fnp-3271	142	8	two	two	NUM
fnp-3271	142	9	families	family	NOUN
fnp-3271	142	10	with	with	ADP
fnp-3271	142	11	a	a	DET
fnp-3271	142	12	history	history	NOUN
fnp-3271	142	13	of	of	ADP
fnp-3271	142	14	pediatric	pediatric	ADJ
fnp-3271	142	15	medulloblastoma	medulloblastoma	NOUN
fnp-3271	142	16	.	.	PUNCT
fnp-3271	143	1	most	most	ADJ
fnp-3271	143	2	elp1	elp1	NOUN
fnp-3271	143	3	-	-	PUNCT
fnp-3271	143	4	associated	associate	VERB
fnp-3271	143	5	medulloblastomas	medulloblastoma	NOUN
fnp-3271	143	6	also	also	ADV
fnp-3271	143	7	exhibited	exhibit	VERB
fnp-3271	143	8	somatic	somatic	ADJ
fnp-3271	143	9	alterations	alteration	NOUN
fnp-3271	143	10	in	in	ADP
fnp-3271	143	11	ptch1	ptch1	PROPN
fnp-3271	143	12	.	.	PUNCT
fnp-3271	144	1	tumors	tumor	NOUN
fnp-3271	144	2	from	from	ADP
fnp-3271	144	3	patients	patient	NOUN
fnp-3271	144	4	with	with	ADP
fnp-3271	144	5	elp1	elp1	PROPN
fnp-3271	144	6	-	-	PUNCT
fnp-3271	144	7	associated	associate	VERB
fnp-3271	144	8	mbshh	mbshh	NOUN
fnp-3271	144	9	were	be	AUX
fnp-3271	144	10	characterized	characterize	VERB
fnp-3271	144	11	by	by	ADP
fnp-3271	144	12	universal	universal	ADJ
fnp-3271	144	13	biallelic	biallelic	ADJ
fnp-3271	144	14	inactivation	inactivation	NOUN
fnp-3271	144	15	of	of	ADP
fnp-3271	144	16	elp1	elp1	NOUN
fnp-3271	144	17	owing	owe	VERB
fnp-3271	144	18	to	to	ADP
fnp-3271	144	19	somatic	somatic	ADJ
fnp-3271	144	20	loss	loss	NOUN
fnp-3271	144	21	of	of	ADP
fnp-3271	144	22	chromosome	chromosome	NOUN
fnp-3271	144	23	arm	arm	NOUN
fnp-3271	144	24	9q	9q	NUM
fnp-3271	144	25	alterations	alteration	NOUN
fnp-3271	144	26	.	.	PUNCT
fnp-3271	145	1	the	the	DET
fnp-3271	145	2	tumor	tumor	NOUN
fnp-3271	145	3	cells	cell	NOUN
fnp-3271	145	4	were	be	AUX
fnp-3271	145	5	found	find	VERB
fnp-3271	145	6	to	to	PART
fnp-3271	145	7	show	show	VERB
fnp-3271	145	8	changes	change	NOUN
fnp-3271	145	9	consistent	consistent	ADJ
fnp-3271	145	10	with	with	ADP
fnp-3271	145	11	loss	loss	NOUN
fnp-3271	145	12	of	of	ADP
fnp-3271	145	13	protein	protein	NOUN
fnp-3271	145	14	homeostasis	homeostasis	NOUN
fnp-3271	145	15	due	due	ADP
fnp-3271	145	16	to	to	ADP
fnp-3271	145	17	elongator	elongator	NOUN
fnp-3271	145	18	deficiency	deficiency	NOUN
fnp-3271	145	19	.	.	PUNCT
fnp-3271	146	1	the	the	DET
fnp-3271	146	2	authors	author	NOUN
fnp-3271	146	3	conclude	conclude	VERB
fnp-3271	146	4	that	that	SCONJ
fnp-3271	146	5	such	such	DET
fnp-3271	146	6	a	a	DET
fnp-3271	146	7	genetic	genetic	ADJ
fnp-3271	146	8	predisposition	predisposition	NOUN
fnp-3271	146	9	to	to	PART
fnp-3271	146	10	proteome	proteome	ADJ
fnp-3271	146	11	instability	instability	NOUN
fnp-3271	146	12	may	may	AUX
fnp-3271	146	13	be	be	AUX
fnp-3271	146	14	a	a	DET
fnp-3271	146	15	determinant	determinant	ADJ
fnp-3271	146	16	in	in	ADP
fnp-3271	146	17	the	the	DET
fnp-3271	146	18	pathogenesis	pathogenesis	NOUN
fnp-3271	146	19	of	of	ADP
fnp-3271	146	20	other	other	ADJ
fnp-3271	146	21	(	(	PUNCT
fnp-3271	146	22	pediatric	pediatric	ADJ
fnp-3271	146	23	)	)	PUNCT
fnp-3271	146	24	cancers	cancer	NOUN
fnp-3271	146	25	as	as	ADV
fnp-3271	146	26	well	well	ADV
fnp-3271	146	27	and	and	CCONJ
fnp-3271	146	28	may	may	AUX
fnp-3271	146	29	provide	provide	VERB
fnp-3271	146	30	new	new	ADJ
fnp-3271	146	31	targets	target	NOUN
fnp-3271	146	32	for	for	ADP
fnp-3271	146	33	therapeutic	therapeutic	ADJ
fnp-3271	146	34	interference	interference	NOUN
fnp-3271	146	35	.	.	PUNCT
fnp-3271	147	1	in	in	ADP
fnp-3271	147	2	another	another	DET
fnp-3271	147	3	study	study	NOUN
fnp-3271	147	4	,	,	PUNCT
fnp-3271	147	5	begemann	begemann	PROPN
fnp-3271	147	6	m	m	PROPN
fnp-3271	147	7	,	,	PUNCT
fnp-3271	147	8	waszak	waszak	PROPN
fnp-3271	147	9	sm	sm	PROPN
fnp-3271	147	10	,	,	PUNCT
fnp-3271	147	11	et	et	PROPN
fnp-3271	147	12	al	al	PROPN
fnp-3271	147	13	(	(	PUNCT
fnp-3271	147	14	last	last	ADJ
fnp-3271	147	15	authors	author	NOUN
fnp-3271	147	16	pfister	pfister	PROPN
fnp-3271	147	17	sm	sm	PROPN
fnp-3271	147	18	,	,	PUNCT
fnp-3271	147	19	kontny	kontny	PROPN
fnp-3271	147	20	u	u	PROPN
fnp-3271	147	21	,	,	PUNCT
fnp-3271	147	22	kurth	kurth	PROPN
fnp-3271	147	23	i	i	PROPN
fnp-3271	147	24	,	,	PUNCT
fnp-3271	147	25	and	and	CCONJ
fnp-3271	147	26	published	publish	VERB
fnp-3271	147	27	in	in	ADP
fnp-3271	147	28	the	the	DET
fnp-3271	147	29	journal	journal	NOUN
fnp-3271	147	30	of	of	ADP
fnp-3271	147	31	clinical	clinical	ADJ
fnp-3271	147	32	oncology	oncology	NOUN
fnp-3271	147	33	)	)	PUNCT
fnp-3271	147	34	investigated	investigate	VERB
fnp-3271	147	35	families	family	NOUN
fnp-3271	147	36	with	with	ADP
fnp-3271	147	37	childhood	childhood	NOUN
fnp-3271	147	38	medulloblastoma	medulloblastoma	NOUN
fnp-3271	147	39	to	to	PART
fnp-3271	147	40	identify	identify	VERB
fnp-3271	147	41	predisposing	predispose	VERB
fnp-3271	147	42	germline	germline	NOUN
fnp-3271	147	43	mutations	mutation	NOUN
fnp-3271	147	44	[	[	X
fnp-3271	147	45	12	12	NUM
fnp-3271	147	46	]	]	PUNCT
fnp-3271	147	47	.	.	PUNCT
fnp-3271	148	1	initial	initial	ADJ
fnp-3271	148	2	findings	finding	NOUN
fnp-3271	148	3	were	be	AUX
fnp-3271	148	4	extended	extend	VERB
fnp-3271	148	5	to	to	ADP
fnp-3271	148	6	genomes	genome	NOUN
fnp-3271	148	7	and	and	CCONJ
fnp-3271	148	8	epigenomes	epigenome	NOUN
fnp-3271	148	9	of	of	ADP
fnp-3271	148	10	1,044	1,044	NUM
fnp-3271	148	11	medulloblastoma	medulloblastoma	ADJ
fnp-3271	148	12	cases	case	NOUN
fnp-3271	148	13	.	.	PUNCT
fnp-3271	149	1	the	the	DET
fnp-3271	149	2	authors	author	NOUN
fnp-3271	149	3	identified	identify	VERB
fnp-3271	149	4	in	in	ADP
fnp-3271	149	5	six	six	NUM
fnp-3271	149	6	patients	patient	NOUN
fnp-3271	149	7	with	with	ADP
fnp-3271	149	8	infant	infant	NOUN
fnp-3271	149	9	-	-	PUNCT
fnp-3271	149	10	onset	onset	VERB
fnp-3271	149	11	medulloblastoma	medulloblastoma	NOUN
fnp-3271	149	12	a	a	DET
fnp-3271	149	13	heterozygous	heterozygous	ADJ
fnp-3271	149	14	germline	germline	NOUN
fnp-3271	149	15	mutation	mutation	NOUN
fnp-3271	149	16	in	in	ADP
fnp-3271	149	17	the	the	DET
fnp-3271	149	18	g	g	PROPN
fnp-3271	149	19	protein	protein	NOUN
fnp-3271	149	20	-	-	PUNCT
fnp-3271	149	21	coupled	couple	VERB
fnp-3271	149	22	receptor	receptor	NOUN
fnp-3271	149	23	161	161	NUM
fnp-3271	149	24	(	(	PUNCT
fnp-3271	149	25	gpr161	gpr161	NOUN
fnp-3271	149	26	)	)	PUNCT
fnp-3271	149	27	gene	gene	NOUN
fnp-3271	149	28	,	,	PUNCT
fnp-3271	149	29	which	which	PRON
fnp-3271	149	30	is	be	AUX
fnp-3271	149	31	located	locate	VERB
fnp-3271	149	32	on	on	ADP
fnp-3271	149	33	chromosome	chromosome	NOUN
fnp-3271	149	34	1q	1q	NUM
fnp-3271	149	35	.	.	PUNCT
fnp-3271	150	1	gpr161	gpr161	NOUN
fnp-3271	150	2	mutations	mutation	NOUN
fnp-3271	150	3	were	be	AUX
fnp-3271	150	4	exclusively	exclusively	ADV
fnp-3271	150	5	associated	associate	VERB
fnp-3271	150	6	with	with	ADP
fnp-3271	150	7	the	the	DET
fnp-3271	150	8	mbshh	mbshh	PROPN
fnp-3271	150	9	subgroup	subgroup	NOUN
fnp-3271	150	10	and	and	CCONJ
fnp-3271	150	11	accounted	account	VERB
fnp-3271	150	12	for	for	ADP
fnp-3271	150	13	5	5	NUM
fnp-3271	150	14	%	%	NOUN
fnp-3271	150	15	of	of	ADP
fnp-3271	150	16	infant	infant	NOUN
fnp-3271	150	17	cases	case	NOUN
fnp-3271	150	18	in	in	ADP
fnp-3271	150	19	these	these	DET
fnp-3271	150	20	cohorts	cohort	NOUN
fnp-3271	150	21	.	.	PUNCT
fnp-3271	151	1	molecular	molecular	ADJ
fnp-3271	151	2	profiling	profiling	NOUN
fnp-3271	151	3	revealed	reveal	VERB
fnp-3271	151	4	loss	loss	NOUN
fnp-3271	151	5	of	of	ADP
fnp-3271	151	6	heterozygosity	heterozygosity	NOUN
fnp-3271	151	7	(	(	PUNCT
fnp-3271	151	8	loh	loh	PROPN
fnp-3271	151	9	)	)	PUNCT
fnp-3271	151	10	at	at	ADP
fnp-3271	151	11	gpr161	gpr161	NOUN
fnp-3271	151	12	in	in	ADP
fnp-3271	151	13	all	all	DET
fnp-3271	151	14	affected	affected	ADJ
fnp-3271	151	15	mbshh	mbshh	NOUN
fnp-3271	151	16	tumors	tumor	NOUN
fnp-3271	151	17	without	without	ADP
fnp-3271	151	18	additional	additional	ADJ
fnp-3271	151	19	somatic	somatic	ADJ
fnp-3271	151	20	driver	driver	NOUN
fnp-3271	151	21	events	event	NOUN
fnp-3271	151	22	.	.	PUNCT
fnp-3271	152	1	additionally	additionally	ADV
fnp-3271	152	2	,	,	PUNCT
fnp-3271	152	3	analysis	analysis	NOUN
fnp-3271	152	4	of	of	ADP
fnp-3271	152	5	226	226	NUM
fnp-3271	152	6	mbshh	mbshh	NOUN
fnp-3271	152	7	tumors	tumor	NOUN
fnp-3271	152	8	revealed	reveal	VERB
fnp-3271	152	9	somatic	somatic	ADJ
fnp-3271	152	10	copy	copy	NOUN
fnp-3271	152	11	-	-	PUNCT
fnp-3271	152	12	neutral	neutral	ADJ
fnp-3271	152	13	loh	loh	PROPN
fnp-3271	152	14	of	of	ADP
fnp-3271	152	15	chromosome	chromosome	NOUN
fnp-3271	152	16	1q	1q	NUM
fnp-3271	152	17	as	as	ADP
fnp-3271	152	18	a	a	DET
fnp-3271	152	19	characteristic	characteristic	ADJ
fnp-3271	152	20	hallmark	hallmark	NOUN
fnp-3271	152	21	and	and	CCONJ
fnp-3271	152	22	the	the	DET
fnp-3271	152	23	primary	primary	ADJ
fnp-3271	152	24	mechanism	mechanism	NOUN
fnp-3271	152	25	for	for	ADP
fnp-3271	152	26	biallelic	biallelic	ADJ
fnp-3271	152	27	inactivation	inactivation	NOUN
fnp-3271	152	28	of	of	ADP
fnp-3271	152	29	gpr161	gpr161	NOUN
fnp-3271	152	30	in	in	ADP
fnp-3271	152	31	the	the	DET
fnp-3271	152	32	affected	affected	ADJ
fnp-3271	152	33	mbshh	mbshh	NOUN
fnp-3271	152	34	tumors	tumor	NOUN
fnp-3271	152	35	.	.	PUNCT
fnp-3271	153	1	obviously	obviously	ADV
fnp-3271	153	2	,	,	PUNCT
fnp-3271	153	3	the	the	DET
fnp-3271	153	4	diagnosis	diagnosis	NOUN
fnp-3271	153	5	of	of	ADP
fnp-3271	153	6	an	an	DET
fnp-3271	153	7	underlying	underlie	VERB
fnp-3271	153	8	predisposition	predisposition	NOUN
fnp-3271	153	9	syndrome	syndrome	NOUN
fnp-3271	153	10	as	as	SCONJ
fnp-3271	153	11	reported	report	VERB
fnp-3271	153	12	in	in	ADP
fnp-3271	153	13	these	these	DET
fnp-3271	153	14	papers	paper	NOUN
fnp-3271	153	15	is	be	AUX
fnp-3271	153	16	important	important	ADJ
fnp-3271	153	17	because	because	SCONJ
fnp-3271	153	18	of	of	ADP
fnp-3271	153	19	its	its	PRON
fnp-3271	153	20	implications	implication	NOUN
fnp-3271	153	21	for	for	ADP
fnp-3271	153	22	the	the	DET
fnp-3271	153	23	management	management	NOUN
fnp-3271	153	24	of	of	ADP
fnp-3271	153	25	the	the	DET
fnp-3271	153	26	patients	patient	NOUN
fnp-3271	153	27	and	and	CCONJ
fnp-3271	153	28	their	their	PRON
fnp-3271	153	29	families	family	NOUN
fnp-3271	153	30	.	.	PUNCT
fnp-3271	154	1	topic	topic	NOUN
fnp-3271	154	2	9	9	NUM
fnp-3271	154	3	.	.	PUNCT
fnp-3271	154	4	liquid	liquid	ADJ
fnp-3271	154	5	biopsy	biopsy	NOUN
fnp-3271	154	6	diagnosis	diagnosis	NOUN
fnp-3271	154	7	of	of	ADP
fnp-3271	154	8	cns	cns	NOUN
fnp-3271	154	9	tumors	tumor	NOUN
fnp-3271	154	10	[	[	X
fnp-3271	154	11	13	13	NUM
fnp-3271	154	12	]	]	PUNCT
fnp-3271	154	13	circulating	circulate	VERB
fnp-3271	154	14	tumor	tumor	NOUN
fnp-3271	154	15	dna	dna	PROPN
fnp-3271	154	16	(	(	PUNCT
fnp-3271	154	17	ctdna	ctdna	NOUN
fnp-3271	154	18	)	)	PUNCT
fnp-3271	154	19	in	in	ADP
fnp-3271	154	20	blood	blood	NOUN
fnp-3271	154	21	is	be	AUX
fnp-3271	154	22	considered	consider	VERB
fnp-3271	154	23	to	to	PART
fnp-3271	154	24	be	be	AUX
fnp-3271	154	25	an	an	DET
fnp-3271	154	26	easily	easily	ADV
fnp-3271	154	27	accessible	accessible	ADJ
fnp-3271	154	28	source	source	NOUN
fnp-3271	154	29	of	of	ADP
fnp-3271	154	30	diagnostic	diagnostic	ADJ
fnp-3271	154	31	,	,	PUNCT
fnp-3271	154	32	prognostic	prognostic	ADJ
fnp-3271	154	33	and/or	and/or	CCONJ
fnp-3271	154	34	predictive	predictive	ADJ
fnp-3271	154	35	information	information	NOUN
fnp-3271	154	36	that	that	PRON
fnp-3271	154	37	may	may	AUX
fnp-3271	154	38	be	be	AUX
fnp-3271	154	39	very	very	ADV
fnp-3271	154	40	helpful	helpful	ADJ
fnp-3271	154	41	for	for	ADP
fnp-3271	154	42	improving	improve	VERB
fnp-3271	154	43	the	the	DET
fnp-3271	154	44	management	management	NOUN
fnp-3271	154	45	of	of	ADP
fnp-3271	154	46	cancer	cancer	NOUN
fnp-3271	154	47	patients	patient	NOUN
fnp-3271	154	48	.	.	PUNCT
fnp-3271	155	1	so	so	ADV
fnp-3271	155	2	far	far	ADV
fnp-3271	155	3	,	,	PUNCT
fnp-3271	155	4	however	however	ADV
fnp-3271	155	5	,	,	PUNCT
fnp-3271	155	6	for	for	ADP
fnp-3271	155	7	patients	patient	NOUN
fnp-3271	155	8	with	with	ADP
fnp-3271	155	9	primary	primary	ADJ
fnp-3271	155	10	brain	brain	NOUN
fnp-3271	155	11	tumors	tumor	NOUN
fnp-3271	155	12	,	,	PUNCT
fnp-3271	155	13	the	the	DET
fnp-3271	155	14	use	use	NOUN
fnp-3271	155	15	of	of	ADP
fnp-3271	155	16	csf	csf	PROPN
fnp-3271	155	17	appeared	appear	VERB
fnp-3271	155	18	to	to	PART
fnp-3271	155	19	be	be	AUX
fnp-3271	155	20	a	a	DET
fnp-3271	155	21	more	more	ADV
fnp-3271	155	22	promising	promising	ADJ
fnp-3271	155	23	biosource	biosource	NOUN
fnp-3271	155	24	because	because	SCONJ
fnp-3271	155	25	of	of	ADP
fnp-3271	155	26	the	the	DET
fnp-3271	155	27	limited	limited	ADJ
fnp-3271	155	28	abundance	abundance	NOUN
fnp-3271	155	29	of	of	ADP
fnp-3271	155	30	ctdna	ctdna	NOUN
fnp-3271	155	31	in	in	ADP
fnp-3271	155	32	blood	blood	NOUN
fnp-3271	155	33	of	of	ADP
fnp-3271	155	34	these	these	DET
fnp-3271	155	35	patients	patient	NOUN
fnp-3271	155	36	.	.	PUNCT
fnp-3271	156	1	at	at	ADP
fnp-3271	156	2	the	the	DET
fnp-3271	156	3	same	same	ADJ
fnp-3271	156	4	time	time	NOUN
fnp-3271	156	5	,	,	PUNCT
fnp-3271	156	6	approaches	approach	VERB
fnp-3271	156	7	that	that	PRON
fnp-3271	156	8	go	go	VERB
fnp-3271	156	9	beyond	beyond	ADP
fnp-3271	156	10	dna	dna	PROPN
fnp-3271	156	11	sequence	sequence	NOUN
fnp-3271	156	12	information	information	NOUN
fnp-3271	156	13	,	,	PUNCT
fnp-3271	156	14	such	such	ADJ
fnp-3271	156	15	as	as	ADP
fnp-3271	156	16	analysis	analysis	NOUN
fnp-3271	156	17	of	of	ADP
fnp-3271	156	18	epigenetic	epigenetic	ADJ
fnp-3271	156	19	signatures	signature	NOUN
fnp-3271	156	20	in	in	ADP
fnp-3271	156	21	ctdna	ctdna	NOUN
fnp-3271	156	22	,	,	PUNCT
fnp-3271	156	23	can	can	AUX
fnp-3271	156	24	help	help	VERB
fnp-3271	156	25	to	to	PART
fnp-3271	156	26	boost	boost	VERB
fnp-3271	156	27	the	the	DET
fnp-3271	156	28	use	use	NOUN
fnp-3271	156	29	of	of	ADP
fnp-3271	156	30	blood	blood	NOUN
fnp-3271	156	31	for	for	ADP
fnp-3271	156	32	liquid	liquid	ADJ
fnp-3271	156	33	biopsy	biopsy	NOUN
fnp-3271	156	34	diagnostics	diagnostic	NOUN
fnp-3271	156	35	[	[	X
fnp-3271	156	36	25	25	NUM
fnp-3271	156	37	]	]	PUNCT
fnp-3271	156	38	.	.	PUNCT
fnp-3271	157	1	in	in	ADP
fnp-3271	157	2	the	the	DET
fnp-3271	157	3	study	study	NOUN
fnp-3271	157	4	published	publish	VERB
fnp-3271	157	5	in	in	ADP
fnp-3271	157	6	nature	nature	NOUN
fnp-3271	157	7	medicine	medicine	NOUN
fnp-3271	157	8	,	,	PUNCT
fnp-3271	157	9	nassiri	nassiri	NOUN
fnp-3271	157	10	f	f	NOUN
fnp-3271	157	11	,	,	PUNCT
fnp-3271	157	12	chakravarthy	chakravarthy	ADJ
fnp-3271	157	13	a	a	PRON
fnp-3271	157	14	,	,	PUNCT
fnp-3271	157	15	feng	feng	PROPN
fnp-3271	157	16	s	s	PROPN
fnp-3271	157	17	,	,	PUNCT
fnp-3271	157	18	et	et	PROPN
fnp-3271	157	19	al	al	PROPN
fnp-3271	157	20	(	(	PUNCT
fnp-3271	157	21	last	last	ADJ
fnp-3271	157	22	authors	author	NOUN
fnp-3271	157	23	zadeh	zadeh	PROPN
fnp-3271	157	24	g	g	PROPN
fnp-3271	157	25	and	and	CCONJ
fnp-3271	157	26	de	de	PROPN
fnp-3271	157	27	carvalho	carvalho	PROPN
fnp-3271	157	28	dd	dd	PROPN
fnp-3271	157	29	)	)	PUNCT
fnp-3271	157	30	used	use	VERB
fnp-3271	157	31	cell	cell	NOUN
fnp-3271	157	32	-	-	PUNCT
fnp-3271	157	33	free	free	ADJ
fnp-3271	157	34	methylated	methylate	VERB
fnp-3271	157	35	dna	dna	NOUN
fnp-3271	157	36	immunoprecipitation	immunoprecipitation	NOUN
fnp-3271	157	37	and	and	CCONJ
fnp-3271	157	38	high	high	ADJ
fnp-3271	157	39	-	-	PUNCT
fnp-3271	157	40	throughput	throughput	NOUN
fnp-3271	157	41	sequencing	sequence	VERB
fnp-3271	157	42	(	(	PUNCT
fnp-3271	157	43	cfmedip	cfmedip	ADJ
fnp-3271	157	44	-	-	PUNCT
fnp-3271	157	45	seq	seq	NOUN
fnp-3271	157	46	)	)	PUNCT
fnp-3271	157	47	to	to	PART
fnp-3271	157	48	recover	recover	VERB
fnp-3271	157	49	and	and	CCONJ
fnp-3271	157	50	profile	profile	VERB
fnp-3271	157	51	methylated	methylate	VERB
fnp-3271	157	52	dna	dna	NOUN
fnp-3271	157	53	fragments	fragment	NOUN
fnp-3271	157	54	from	from	ADP
fnp-3271	157	55	plasma	plasma	NOUN
fnp-3271	157	56	[	[	X
fnp-3271	157	57	13	13	NUM
fnp-3271	157	58	]	]	PUNCT
fnp-3271	157	59	.	.	PUNCT
fnp-3271	158	1	plasma	plasma	NOUN
fnp-3271	158	2	samples	sample	NOUN
fnp-3271	158	3	of	of	ADP
fnp-3271	158	4	patients	patient	NOUN
fnp-3271	158	5	with	with	ADP
fnp-3271	158	6	diffuse	diffuse	NOUN
fnp-3271	158	7	(	(	PUNCT
fnp-3271	158	8	idh	idh	NOUN
fnp-3271	158	9	-	-	PUNCT
fnp-3271	158	10	wildtype	wildtype	NOUN
fnp-3271	158	11	and	and	CCONJ
fnp-3271	158	12	idh	idh	NOUN
fnp-3271	158	13	-	-	PUNCT
fnp-3271	158	14	mutant	mutant	NOUN
fnp-3271	158	15	)	)	PUNCT
fnp-3271	158	16	gliomas	glioma	NOUN
fnp-3271	158	17	,	,	PUNCT
fnp-3271	158	18	of	of	ADP
fnp-3271	158	19	patients	patient	NOUN
fnp-3271	158	20	with	with	ADP
fnp-3271	158	21	other	other	ADJ
fnp-3271	158	22	intracranial	intracranial	ADJ
fnp-3271	158	23	and	and	CCONJ
fnp-3271	158	24	extracranial	extracranial	ADJ
fnp-3271	158	25	tumors	tumor	NOUN
fnp-3271	158	26	,	,	PUNCT
fnp-3271	158	27	and	and	CCONJ
fnp-3271	158	28	of	of	ADP
fnp-3271	158	29	healthy	healthy	ADJ
fnp-3271	158	30	controls	control	NOUN
fnp-3271	158	31	were	be	AUX
fnp-3271	158	32	used	use	VERB
fnp-3271	158	33	.	.	PUNCT
fnp-3271	159	1	these	these	DET
fnp-3271	159	2	samples	sample	NOUN
fnp-3271	159	3	were	be	AUX
fnp-3271	159	4	split	split	VERB
fnp-3271	159	5	into	into	ADP
fnp-3271	159	6	training	training	NOUN
fnp-3271	159	7	and	and	CCONJ
fnp-3271	159	8	test	test	NOUN
fnp-3271	159	9	sets	set	NOUN
fnp-3271	159	10	,	,	PUNCT
fnp-3271	159	11	and	and	CCONJ
fnp-3271	159	12	random	random	ADJ
fnp-3271	159	13	forest	forest	NOUN
fnp-3271	159	14	classifiers	classifier	NOUN
fnp-3271	159	15	were	be	AUX
fnp-3271	159	16	trained	train	VERB
fnp-3271	159	17	using	use	VERB
fnp-3271	159	18	the	the	DET
fnp-3271	159	19	top	top	ADJ
fnp-3271	159	20	300	300	NUM
fnp-3271	159	21	differentially	differentially	ADV
fnp-3271	159	22	methylated	methylate	VERB
fnp-3271	159	23	regions	region	NOUN
fnp-3271	159	24	for	for	ADP
fnp-3271	159	25	the	the	DET
fnp-3271	159	26	different	different	ADJ
fnp-3271	159	27	tumor	tumor	NOUN
fnp-3271	159	28	classes	class	NOUN
fnp-3271	159	29	.	.	PUNCT
fnp-3271	160	1	indeed	indeed	ADV
fnp-3271	160	2	,	,	PUNCT
fnp-3271	160	3	the	the	DET
fnp-3271	160	4	classifier	classifier	NOUN
fnp-3271	160	5	was	be	AUX
fnp-3271	160	6	able	able	ADJ
fnp-3271	160	7	to	to	PART
fnp-3271	160	8	accurately	accurately	ADV
fnp-3271	160	9	distinguish	distinguish	VERB
fnp-3271	160	10	different	different	ADJ
fnp-3271	160	11	tumors	tumor	NOUN
fnp-3271	160	12	based	base	VERB
fnp-3271	160	13	on	on	ADP
fnp-3271	160	14	the	the	DET
fnp-3271	160	15	differences	difference	NOUN
fnp-3271	160	16	in	in	ADP
fnp-3271	160	17	dna	dna	PROPN
fnp-3271	160	18	methylation	methylation	NOUN
fnp-3271	160	19	profiles	profile	NOUN
fnp-3271	160	20	.	.	PUNCT
fnp-3271	161	1	the	the	DET
fnp-3271	161	2	potential	potential	NOUN
fnp-3271	161	3	of	of	ADP
fnp-3271	161	4	such	such	DET
fnp-3271	161	5	a	a	DET
fnp-3271	161	6	methylome	methylome	ADV
fnp-3271	161	7	-	-	PUNCT
fnp-3271	161	8	based	base	VERB
fnp-3271	161	9	liquid	liquid	ADJ
fnp-3271	161	10	biopsy	biopsy	NOUN
fnp-3271	161	11	approach	approach	NOUN
fnp-3271	161	12	has	have	AUX
fnp-3271	161	13	also	also	ADV
fnp-3271	161	14	already	already	ADV
fnp-3271	161	15	been	be	AUX
fnp-3271	161	16	reported	report	VERB
fnp-3271	161	17	for	for	ADP
fnp-3271	161	18	non	non	ADJ
fnp-3271	161	19	-	-	ADJ
fnp-3271	161	20	cns	cns	ADJ
fnp-3271	161	21	tumors	tumor	NOUN
fnp-3271	161	22	and	and	CCONJ
fnp-3271	161	23	can	can	AUX
fnp-3271	161	24	be	be	AUX
fnp-3271	161	25	applied	apply	VERB
fnp-3271	161	26	to	to	ADP
fnp-3271	161	27	other	other	ADJ
fnp-3271	161	28	biosources	biosource	NOUN
fnp-3271	161	29	(	(	PUNCT
fnp-3271	161	30	e.g.	e.g.	ADV
fnp-3271	161	31	urine	urine	NOUN
fnp-3271	161	32	)	)	PUNCT
fnp-3271	161	33	as	as	ADV
fnp-3271	161	34	well	well	ADV
fnp-3271	162	1	[	[	X
fnp-3271	162	2	26	26	NUM
fnp-3271	162	3	,	,	PUNCT
fnp-3271	162	4	27	27	NUM
fnp-3271	162	5	]	]	PUNCT
fnp-3271	162	6	,	,	PUNCT
fnp-3271	162	7	underscoring	underscore	VERB
fnp-3271	162	8	the	the	DET
fnp-3271	162	9	potential	potential	NOUN
fnp-3271	162	10	of	of	ADP
fnp-3271	162	11	analysis	analysis	NOUN
fnp-3271	162	12	of	of	ADP
fnp-3271	162	13	methylated	methylate	VERB
fnp-3271	162	14	plasma	plasma	NOUN
fnp-3271	162	15	ctdna	ctdna	NOUN
fnp-3271	162	16	to	to	PART
fnp-3271	162	17	facilitate	facilitate	VERB
fnp-3271	162	18	blood	blood	NOUN
fnp-3271	162	19	-	-	PUNCT
fnp-3271	162	20	based	base	VERB
fnp-3271	162	21	diagnosis	diagnosis	NOUN
fnp-3271	162	22	and	and	CCONJ
fnp-3271	162	23	monitoring	monitoring	NOUN
fnp-3271	162	24	of	of	ADP
fnp-3271	162	25	patients	patient	NOUN
fnp-3271	162	26	with	with	ADP
fnp-3271	162	27	cancer	cancer	NOUN
fnp-3271	162	28	.	.	PUNCT
fnp-3271	163	1	topic	topic	NOUN
fnp-3271	163	2	10	10	NUM
fnp-3271	163	3	.	.	PUNCT
fnp-3271	164	1	the	the	DET
fnp-3271	164	2	glioblastoma	glioblastoma	NOUN
fnp-3271	164	3	microbiome	microbiome	NOUN
fnp-3271	164	4	[	[	X
fnp-3271	164	5	14	14	NUM
fnp-3271	164	6	]	]	PUNCT
fnp-3271	164	7	tumor	tumor	NOUN
fnp-3271	164	8	formation	formation	NOUN
fnp-3271	164	9	involves	involve	VERB
fnp-3271	164	10	the	the	DET
fnp-3271	164	11	co	co	NOUN
fnp-3271	164	12	-	-	NOUN
fnp-3271	164	13	evolution	evolution	NOUN
fnp-3271	164	14	of	of	ADP
fnp-3271	164	15	neoplastic	neoplastic	ADJ
fnp-3271	164	16	cells	cell	NOUN
fnp-3271	164	17	together	together	ADV
fnp-3271	164	18	with	with	ADP
fnp-3271	164	19	extracellular	extracellular	ADJ
fnp-3271	164	20	matrix	matrix	NOUN
fnp-3271	164	21	,	,	PUNCT
fnp-3271	164	22	tumor	tumor	NOUN
fnp-3271	164	23	vasculature	vasculature	NOUN
fnp-3271	164	24	and	and	CCONJ
fnp-3271	164	25	immune	immune	ADJ
fnp-3271	164	26	cells	cell	NOUN
fnp-3271	164	27	.	.	PUNCT
fnp-3271	165	1	evaluating	evaluate	VERB
fnp-3271	165	2	tumors	tumor	NOUN
fnp-3271	165	3	as	as	ADP
fnp-3271	165	4	complete	complete	ADJ
fnp-3271	165	5	‘	'	PUNCT
fnp-3271	165	6	organs	organ	NOUN
fnp-3271	165	7	’	'	PUNCT
fnp-3271	165	8	,	,	PUNCT
fnp-3271	165	9	and	and	CCONJ
fnp-3271	165	10	not	not	PART
fnp-3271	165	11	simply	simply	ADV
fnp-3271	165	12	as	as	ADP
fnp-3271	165	13	masses	masse	NOUN
fnp-3271	165	14	of	of	ADP
fnp-3271	165	15	transformed	transform	VERB
fnp-3271	165	16	tumor	tumor	NOUN
fnp-3271	165	17	cells	cell	NOUN
fnp-3271	165	18	,	,	PUNCT
fnp-3271	165	19	is	be	AUX
fnp-3271	165	20	of	of	ADP
fnp-3271	165	21	paramount	paramount	ADJ
fnp-3271	165	22	importance	importance	NOUN
fnp-3271	165	23	because	because	SCONJ
fnp-3271	165	24	heterologous	heterologous	ADJ
fnp-3271	165	25	cell	cell	NOUN
fnp-3271	165	26	types	type	NOUN
fnp-3271	165	27	within	within	ADP
fnp-3271	165	28	tumors	tumor	NOUN
fnp-3271	165	29	can	can	AUX
fnp-3271	165	30	actively	actively	ADV
fnp-3271	165	31	influence	influence	VERB
fnp-3271	165	32	therapeutic	therapeutic	ADJ
fnp-3271	165	33	response	response	NOUN
fnp-3271	166	1	[	[	X
fnp-3271	166	2	28	28	NUM
fnp-3271	166	3	]	]	PUNCT
fnp-3271	166	4	.	.	PUNCT
fnp-3271	167	1	bacteria	bacteria	NOUN
fnp-3271	167	2	were	be	AUX
fnp-3271	167	3	first	first	ADV
fnp-3271	167	4	detected	detect	VERB
fnp-3271	167	5	in	in	ADP
fnp-3271	167	6	human	human	ADJ
fnp-3271	167	7	tumors	tumor	NOUN
fnp-3271	167	8	more	more	ADJ
fnp-3271	167	9	than	than	ADP
fnp-3271	167	10	100	100	NUM
fnp-3271	167	11	years	year	NOUN
fnp-3271	167	12	ago	ago	ADV
fnp-3271	167	13	,	,	PUNCT
fnp-3271	167	14	raising	raise	VERB
fnp-3271	167	15	the	the	DET
fnp-3271	167	16	possibility	possibility	NOUN
fnp-3271	167	17	that	that	SCONJ
fnp-3271	167	18	the	the	DET
fnp-3271	167	19	tumor	tumor	NOUN
fnp-3271	167	20	microbiome	microbiome	NOUN
fnp-3271	167	21	may	may	AUX
fnp-3271	167	22	be	be	AUX
fnp-3271	167	23	an	an	DET
fnp-3271	167	24	additional	additional	ADJ
fnp-3271	167	25	player	player	NOUN
fnp-3271	167	26	in	in	ADP
fnp-3271	167	27	the	the	DET
fnp-3271	167	28	complex	complex	ADJ
fnp-3271	167	29	tumor	tumor	NOUN
fnp-3271	167	30	ecosystem	ecosystem	NOUN
fnp-3271	167	31	.	.	PUNCT
fnp-3271	168	1	however	however	ADV
fnp-3271	168	2	,	,	PUNCT
fnp-3271	168	3	the	the	DET
fnp-3271	168	4	existence	existence	NOUN
fnp-3271	168	5	of	of	ADP
fnp-3271	168	6	the	the	DET
fnp-3271	168	7	tumor	tumor	NOUN
fnp-3271	168	8	microbiome	microbiome	NOUN
fnp-3271	168	9	remained	remain	VERB
fnp-3271	168	10	an	an	DET
fnp-3271	168	11	issue	issue	NOUN
fnp-3271	168	12	of	of	ADP
fnp-3271	168	13	debate	debate	NOUN
fnp-3271	168	14	because	because	SCONJ
fnp-3271	168	15	of	of	ADP
fnp-3271	168	16	the	the	DET
fnp-3271	168	17	suspicion	suspicion	NOUN
fnp-3271	168	18	of	of	ADP
fnp-3271	168	19	sample	sample	NOUN
fnp-3271	168	20	contamination	contamination	NOUN
fnp-3271	168	21	.	.	PUNCT
fnp-3271	169	1	in	in	ADP
fnp-3271	169	2	their	their	PRON
fnp-3271	169	3	study	study	NOUN
fnp-3271	169	4	published	publish	VERB
fnp-3271	169	5	in	in	ADP
fnp-3271	169	6	science	science	NOUN
fnp-3271	169	7	,	,	PUNCT
fnp-3271	169	8	nejman	nejman	NOUN
fnp-3271	169	9	d	d	PROPN
fnp-3271	169	10	,	,	PUNCT
fnp-3271	169	11	livyatan	livyatan	PROPN
fnp-3271	169	12	i	i	PRON
fnp-3271	169	13	,	,	PUNCT
fnp-3271	169	14	fuks	fuks	PROPN
fnp-3271	169	15	g	g	PROPN
fnp-3271	169	16	,	,	PUNCT
fnp-3271	169	17	et	et	PROPN
fnp-3271	169	18	al	al	PROPN
fnp-3271	169	19	(	(	PUNCT
fnp-3271	169	20	last	last	ADJ
fnp-3271	169	21	authors	author	NOUN
fnp-3271	169	22	shental	shental	ADJ
fnp-3271	169	23	n	n	CCONJ
fnp-3271	169	24	,	,	PUNCT
fnp-3271	169	25	straussman	straussman	NOUN
fnp-3271	169	26	r	r	NOUN
fnp-3271	169	27	)	)	PUNCT
fnp-3271	169	28	characterized	characterize	VERB
fnp-3271	169	29	the	the	DET
fnp-3271	169	30	microbiome	microbiome	NOUN
fnp-3271	169	31	of	of	ADP
fnp-3271	169	32	1010	1010	NUM
fnp-3271	169	33	tumor	tumor	NOUN
fnp-3271	169	34	samples	sample	NOUN
fnp-3271	169	35	from	from	ADP
fnp-3271	169	36	seven	seven	NUM
fnp-3271	169	37	human	human	ADJ
fnp-3271	169	38	cancer	cancer	NOUN
fnp-3271	169	39	types	type	NOUN
fnp-3271	169	40	(	(	PUNCT
fnp-3271	169	41	breast	breast	NOUN
fnp-3271	169	42	,	,	PUNCT
fnp-3271	169	43	lung	lung	NOUN
fnp-3271	169	44	,	,	PUNCT
fnp-3271	169	45	ovary	ovary	ADJ
fnp-3271	169	46	,	,	PUNCT
fnp-3271	169	47	pancreas	pancrea	NOUN
fnp-3271	169	48	,	,	PUNCT
fnp-3271	169	49	melanoma	melanoma	NOUN
fnp-3271	169	50	,	,	PUNCT
fnp-3271	169	51	bone	bone	NOUN
fnp-3271	169	52	,	,	PUNCT
fnp-3271	169	53	and	and	CCONJ
fnp-3271	169	54	brain	brain	NOUN
fnp-3271	169	55	/	/	SYM
fnp-3271	169	56	glioblastoma	glioblastoma	NOUN
fnp-3271	169	57	)	)	PUNCT
fnp-3271	169	58	as	as	ADV
fnp-3271	169	59	well	well	ADV
fnp-3271	169	60	as	as	ADP
fnp-3271	169	61	of	of	ADP
fnp-3271	169	62	516	516	NUM
fnp-3271	169	63	normal	normal	ADJ
fnp-3271	169	64	samples	sample	NOUN
fnp-3271	169	65	(	(	PUNCT
fnp-3271	169	66	including	include	VERB
fnp-3271	169	67	normal	normal	ADJ
fnp-3271	169	68	tissue	tissue	NOUN
fnp-3271	169	69	adjacent	adjacent	ADJ
fnp-3271	169	70	to	to	ADP
fnp-3271	169	71	the	the	DET
fnp-3271	169	72	tumor	tumor	NOUN
fnp-3271	169	73	from	from	ADP
fnp-3271	169	74	the	the	DET
fnp-3271	169	75	same	same	ADJ
fnp-3271	169	76	patients	patient	NOUN
fnp-3271	169	77	)	)	PUNCT
fnp-3271	170	1	[	[	X
fnp-3271	170	2	14	14	NUM
fnp-3271	170	3	]	]	PUNCT
fnp-3271	170	4	.	.	PUNCT
fnp-3271	171	1	the	the	DET
fnp-3271	171	2	authors	author	NOUN
fnp-3271	171	3	took	take	VERB
fnp-3271	171	4	multiple	multiple	ADJ
fnp-3271	171	5	measures	measure	NOUN
fnp-3271	171	6	to	to	PART
fnp-3271	171	7	minimize	minimize	VERB
fnp-3271	171	8	and	and	CCONJ
fnp-3271	171	9	control	control	VERB
fnp-3271	171	10	for	for	ADP
fnp-3271	171	11	contamination	contamination	NOUN
fnp-3271	171	12	.	.	PUNCT
fnp-3271	172	1	they	they	PRON
fnp-3271	172	2	used	use	VERB
fnp-3271	172	3	pcr	pcr	NOUN
fnp-3271	172	4	sequencing	sequencing	NOUN
fnp-3271	172	5	techniques	technique	NOUN
fnp-3271	172	6	to	to	PART
fnp-3271	172	7	gain	gain	VERB
fnp-3271	172	8	species	species	NOUN
fnp-3271	172	9	-	-	PUNCT
fnp-3271	172	10	level	level	NOUN
fnp-3271	172	11	resolution	resolution	NOUN
fnp-3271	172	12	as	as	ADV
fnp-3271	172	13	well	well	ADV
fnp-3271	172	14	as	as	ADP
fnp-3271	172	15	multiple	multiple	ADJ
fnp-3271	172	16	visualization	visualization	NOUN
fnp-3271	172	17	methods	method	NOUN
fnp-3271	172	18	and	and	CCONJ
fnp-3271	172	19	‘	'	PUNCT
fnp-3271	172	20	culturomics	culturomic	NOUN
fnp-3271	172	21	’	'	PUNCT
fnp-3271	172	22	for	for	ADP
fnp-3271	172	23	identification	identification	NOUN
fnp-3271	172	24	of	of	ADP
fnp-3271	172	25	bacteria	bacteria	NOUN
fnp-3271	172	26	.	.	PUNCT
fnp-3271	173	1	the	the	DET
fnp-3271	173	2	authors	author	NOUN
fnp-3271	173	3	report	report	VERB
fnp-3271	173	4	the	the	DET
fnp-3271	173	5	presence	presence	NOUN
fnp-3271	173	6	of	of	ADP
fnp-3271	173	7	bacteria	bacteria	NOUN
fnp-3271	173	8	in	in	ADP
fnp-3271	173	9	each	each	DET
fnp-3271	173	10	tumor	tumor	NOUN
fnp-3271	173	11	type	type	NOUN
fnp-3271	173	12	,	,	PUNCT
fnp-3271	173	13	including	include	VERB
fnp-3271	173	14	in	in	ADP
fnp-3271	173	15	tumors	tumor	NOUN
fnp-3271	173	16	that	that	PRON
fnp-3271	173	17	have	have	VERB
fnp-3271	173	18	no	no	DET
fnp-3271	173	19	direct	direct	ADJ
fnp-3271	173	20	connection	connection	NOUN
fnp-3271	173	21	with	with	ADP
fnp-3271	173	22	the	the	DET
fnp-3271	173	23	external	external	ADJ
fnp-3271	173	24	environment	environment	NOUN
fnp-3271	173	25	such	such	ADJ
fnp-3271	173	26	as	as	ADP
fnp-3271	173	27	glioblastomas	glioblastoma	NOUN
fnp-3271	173	28	.	.	PUNCT
fnp-3271	174	1	the	the	DET
fnp-3271	174	2	detection	detection	NOUN
fnp-3271	174	3	rate	rate	NOUN
fnp-3271	174	4	ranged	range	VERB
fnp-3271	174	5	from	from	ADP
fnp-3271	174	6	14.3	14.3	NUM
fnp-3271	174	7	%	%	NOUN
fnp-3271	174	8	in	in	ADP
fnp-3271	174	9	melanomas	melanomas	PROPN
fnp-3271	174	10	to	to	ADP
fnp-3271	174	11	>	>	X
fnp-3271	174	12	60	60	NUM
fnp-3271	174	13	%	%	NOUN
fnp-3271	174	14	in	in	ADP
fnp-3271	174	15	breast	breast	NOUN
fnp-3271	174	16	,	,	PUNCT
fnp-3271	174	17	pancreatic	pancreatic	ADJ
fnp-3271	174	18	,	,	PUNCT
fnp-3271	174	19	and	and	CCONJ
fnp-3271	174	20	bone	bone	NOUN
fnp-3271	174	21	tumors	tumor	NOUN
fnp-3271	174	22	.	.	PUNCT
fnp-3271	175	1	breast	breast	NOUN
fnp-3271	175	2	tumors	tumor	NOUN
fnp-3271	175	3	had	have	VERB
fnp-3271	175	4	a	a	DET
fnp-3271	175	5	richer	rich	ADJ
fnp-3271	175	6	and	and	CCONJ
fnp-3271	175	7	more	more	ADV
fnp-3271	175	8	diverse	diverse	ADJ
fnp-3271	175	9	microbiome	microbiome	NOUN
fnp-3271	175	10	than	than	ADP
fnp-3271	175	11	all	all	DET
fnp-3271	175	12	other	other	ADJ
fnp-3271	175	13	tumor	tumor	NOUN
fnp-3271	175	14	types	type	NOUN
fnp-3271	175	15	tested	test	VERB
fnp-3271	175	16	,	,	PUNCT
fnp-3271	175	17	and	and	CCONJ
fnp-3271	175	18	live	live	ADJ
fnp-3271	175	19	bacteria	bacteria	NOUN
fnp-3271	175	20	could	could	AUX
fnp-3271	175	21	be	be	AUX
fnp-3271	175	22	cultured	cultured	ADJ
fnp-3271	175	23	from	from	ADP
fnp-3271	175	24	these	these	DET
fnp-3271	175	25	tumors	tumor	NOUN
fnp-3271	175	26	.	.	PUNCT
fnp-3271	176	1	the	the	DET
fnp-3271	176	2	bacteria	bacteria	NOUN
fnp-3271	176	3	were	be	AUX
fnp-3271	176	4	found	find	VERB
fnp-3271	176	5	to	to	PART
fnp-3271	176	6	be	be	AUX
fnp-3271	176	7	predominantly	predominantly	ADV
fnp-3271	176	8	localized	localize	VERB
fnp-3271	176	9	intracellularly	intracellularly	ADV
fnp-3271	176	10	in	in	ADP
fnp-3271	176	11	both	both	PRON
fnp-3271	176	12	cancer	cancer	NOUN
fnp-3271	176	13	cells	cell	NOUN
fnp-3271	176	14	and	and	CCONJ
fnp-3271	176	15	immune	immune	ADJ
fnp-3271	176	16	cells	cell	NOUN
fnp-3271	176	17	,	,	PUNCT
fnp-3271	176	18	with	with	ADP
fnp-3271	176	19	different	different	ADJ
fnp-3271	176	20	tumor	tumor	NOUN
fnp-3271	176	21	types	type	NOUN
fnp-3271	176	22	showing	show	VERB
fnp-3271	176	23	a	a	DET
fnp-3271	176	24	distinct	distinct	ADJ
fnp-3271	176	25	microbiome	microbiome	NOUN
fnp-3271	176	26	composition	composition	NOUN
fnp-3271	176	27	.	.	PUNCT
fnp-3271	177	1	the	the	DET
fnp-3271	177	2	authors	author	NOUN
fnp-3271	177	3	also	also	ADV
fnp-3271	177	4	noted	note	VERB
fnp-3271	177	5	correlations	correlation	NOUN
fnp-3271	177	6	between	between	ADP
fnp-3271	177	7	intratumor	intratumor	PROPN
fnp-3271	177	8	bacteria	bacteria	NOUN
fnp-3271	177	9	and	and	CCONJ
fnp-3271	177	10	the	the	DET
fnp-3271	177	11	smoking	smoking	NOUN
fnp-3271	177	12	status	status	NOUN
fnp-3271	177	13	and/or	and/or	CCONJ
fnp-3271	177	14	the	the	DET
fnp-3271	177	15	response	response	NOUN
fnp-3271	177	16	to	to	ADP
fnp-3271	177	17	immunotherapy	immunotherapy	NOUN
fnp-3271	177	18	of	of	ADP
fnp-3271	177	19	the	the	DET
fnp-3271	177	20	patients	patient	NOUN
fnp-3271	177	21	.	.	PUNCT
fnp-3271	178	1	obviously	obviously	ADV
fnp-3271	178	2	,	,	PUNCT
fnp-3271	178	3	these	these	DET
fnp-3271	178	4	findings	finding	NOUN
fnp-3271	178	5	immediately	immediately	ADV
fnp-3271	178	6	raise	raise	VERB
fnp-3271	178	7	additional	additional	ADJ
fnp-3271	178	8	questions	question	NOUN
fnp-3271	178	9	,	,	PUNCT
fnp-3271	178	10	for	for	ADP
fnp-3271	178	11	example	example	NOUN
fnp-3271	178	12	:	:	PUNCT
fnp-3271	178	13	what	what	PRON
fnp-3271	178	14	(	(	PUNCT
fnp-3271	178	15	if	if	SCONJ
fnp-3271	178	16	any	any	PRON
fnp-3271	178	17	)	)	PUNCT
fnp-3271	178	18	is	be	AUX
fnp-3271	178	19	the	the	DET
fnp-3271	178	20	role	role	NOUN
fnp-3271	178	21	of	of	ADP
fnp-3271	178	22	intratumoral	intratumoral	ADJ
fnp-3271	178	23	bacteria	bacteria	NOUN
fnp-3271	178	24	in	in	ADP
fnp-3271	178	25	the	the	DET
fnp-3271	178	26	development	development	NOUN
fnp-3271	178	27	of	of	ADP
fnp-3271	178	28	cancer	cancer	NOUN
fnp-3271	178	29	?	?	PUNCT
fnp-3271	179	1	and	and	CCONJ
fnp-3271	179	2	how	how	SCONJ
fnp-3271	179	3	does	do	AUX
fnp-3271	179	4	the	the	DET
fnp-3271	179	5	tumor	tumor	NOUN
fnp-3271	179	6	microbiome	microbiome	NOUN
fnp-3271	179	7	affect	affect	VERB
fnp-3271	179	8	the	the	DET
fnp-3271	179	9	immune	immune	ADJ
fnp-3271	179	10	tumor	tumor	NOUN
fnp-3271	179	11	microenvironment	microenvironment	NOUN
fnp-3271	179	12	and	and	CCONJ
fnp-3271	179	13	the	the	DET
fnp-3271	179	14	response	response	NOUN
fnp-3271	179	15	to	to	ADP
fnp-3271	179	16	immune	immune	ADJ
fnp-3271	179	17	therapy	therapy	NOUN
fnp-3271	179	18	?	?	PUNCT
fnp-3271	180	1	the	the	DET
fnp-3271	180	2	answers	answer	NOUN
fnp-3271	180	3	to	to	ADP
fnp-3271	180	4	such	such	ADJ
fnp-3271	180	5	questions	question	NOUN
fnp-3271	180	6	are	be	AUX
fnp-3271	180	7	crucial	crucial	ADJ
fnp-3271	180	8	for	for	ADP
fnp-3271	180	9	further	further	ADJ
fnp-3271	180	10	elucidation	elucidation	NOUN
fnp-3271	180	11	of	of	ADP
fnp-3271	180	12	the	the	DET
fnp-3271	180	13	existence	existence	NOUN
fnp-3271	180	14	and	and	CCONJ
fnp-3271	180	15	the	the	DET
fnp-3271	180	16	importance	importance	NOUN
fnp-3271	180	17	of	of	ADP
fnp-3271	180	18	the	the	DET
fnp-3271	180	19	tumor	tumor	NOUN
fnp-3271	180	20	microbiome	microbiome	NOUN
fnp-3271	180	21	in	in	ADP
fnp-3271	180	22	cancer	cancer	NOUN
fnp-3271	180	23	[	[	X
fnp-3271	180	24	29	29	NUM
fnp-3271	180	25	]	]	PUNCT
fnp-3271	180	26	.	.	PUNCT
fnp-3271	181	1	discussion	discussion	NOUN
fnp-3271	181	2	hopefully	hopefully	ADV
fnp-3271	181	3	,	,	PUNCT
fnp-3271	181	4	this	this	DET
fnp-3271	181	5	review	review	NOUN
fnp-3271	181	6	indeed	indeed	ADV
fnp-3271	181	7	provides	provide	VERB
fnp-3271	181	8	concise	concise	ADJ
fnp-3271	181	9	,	,	PUNCT
fnp-3271	181	10	easily	easily	ADV
fnp-3271	181	11	digestible	digestible	VERB
fnp-3271	181	12	information	information	NOUN
fnp-3271	181	13	on	on	ADP
fnp-3271	181	14	the	the	DET
fnp-3271	181	15	topics	topic	NOUN
fnp-3271	181	16	selected	select	VERB
fnp-3271	181	17	by	by	ADP
fnp-3271	181	18	the	the	DET
fnp-3271	181	19	author	author	NOUN
fnp-3271	181	20	as	as	ADP
fnp-3271	181	21	the	the	DET
fnp-3271	181	22	top	top	ADJ
fnp-3271	181	23	10	10	NUM
fnp-3271	181	24	discoveries	discovery	NOUN
fnp-3271	181	25	in	in	ADP
fnp-3271	181	26	the	the	DET
fnp-3271	181	27	year	year	NOUN
fnp-3271	181	28	2020	2020	NUM
fnp-3271	181	29	.	.	PUNCT
fnp-3271	182	1	of	of	ADP
fnp-3271	182	2	course	course	NOUN
fnp-3271	182	3	,	,	PUNCT
fnp-3271	182	4	during	during	ADP
fnp-3271	182	5	the	the	DET
fnp-3271	182	6	selection	selection	NOUN
fnp-3271	182	7	process	process	NOUN
fnp-3271	182	8	,	,	PUNCT
fnp-3271	182	9	quite	quite	DET
fnp-3271	182	10	a	a	DET
fnp-3271	182	11	few	few	ADJ
fnp-3271	182	12	papers	paper	NOUN
fnp-3271	182	13	were	be	AUX
fnp-3271	182	14	noted	note	VERB
fnp-3271	182	15	that	that	SCONJ
fnp-3271	182	16	did	do	AUX
fnp-3271	182	17	n’t	not	PART
fnp-3271	182	18	make	make	VERB
fnp-3271	182	19	it	it	PRON
fnp-3271	182	20	to	to	ADP
fnp-3271	182	21	the	the	DET
fnp-3271	182	22	top	top	ADJ
fnp-3271	182	23	10	10	NUM
fnp-3271	182	24	list	list	NOUN
fnp-3271	182	25	but	but	CCONJ
fnp-3271	182	26	that	that	PRON
fnp-3271	182	27	are	be	AUX
fnp-3271	182	28	certainly	certainly	ADV
fnp-3271	182	29	of	of	ADP
fnp-3271	182	30	great	great	ADJ
fnp-3271	182	31	interest	interest	NOUN
fnp-3271	182	32	as	as	ADV
fnp-3271	182	33	well	well	ADV
fnp-3271	182	34	.	.	PUNCT
fnp-3271	183	1	for	for	ADP
fnp-3271	183	2	example	example	NOUN
fnp-3271	183	3	,	,	PUNCT
fnp-3271	183	4	it	it	PRON
fnp-3271	183	5	is	be	AUX
fnp-3271	183	6	reassuring	reassuring	ADJ
fnp-3271	183	7	to	to	PART
fnp-3271	183	8	learn	learn	VERB
fnp-3271	183	9	that	that	SCONJ
fnp-3271	183	10	the	the	DET
fnp-3271	183	11	use	use	NOUN
fnp-3271	183	12	of	of	ADP
fnp-3271	183	13	molecular	molecular	ADJ
fnp-3271	183	14	markers	marker	NOUN
fnp-3271	183	15	for	for	ADP
fnp-3271	183	16	the	the	DET
fnp-3271	183	17	diagnosis	diagnosis	NOUN
fnp-3271	183	18	of	of	ADP
fnp-3271	183	19	glioblastoma	glioblastoma	NOUN
fnp-3271	183	20	,	,	PUNCT
fnp-3271	183	21	idh	idh	NOUN
fnp-3271	183	22	-	-	PUNCT
fnp-3271	183	23	wildtype	wildtype	NOUN
fnp-3271	183	24	as	as	SCONJ
fnp-3271	183	25	suggested	suggest	VERB
fnp-3271	183	26	by	by	ADP
fnp-3271	183	27	cimpact	cimpact	ADJ
fnp-3271	183	28	-	-	PUNCT
fnp-3271	183	29	now	now	ADV
fnp-3271	183	30	update	update	NOUN
fnp-3271	183	31	3	3	NUM
fnp-3271	183	32	was	be	AUX
fnp-3271	183	33	corroborated	corroborate	VERB
fnp-3271	183	34	in	in	ADP
fnp-3271	183	35	an	an	DET
fnp-3271	183	36	independent	independent	ADJ
fnp-3271	183	37	study	study	NOUN
fnp-3271	183	38	[	[	X
fnp-3271	183	39	30	30	NUM
fnp-3271	183	40	,	,	PUNCT
fnp-3271	183	41	31	31	NUM
fnp-3271	183	42	]	]	PUNCT
fnp-3271	183	43	,	,	PUNCT
fnp-3271	183	44	but	but	CCONJ
fnp-3271	183	45	it	it	PRON
fnp-3271	183	46	is	be	AUX
fnp-3271	183	47	also	also	ADV
fnp-3271	183	48	good	good	ADJ
fnp-3271	183	49	to	to	PART
fnp-3271	183	50	know	know	VERB
fnp-3271	183	51	that	that	SCONJ
fnp-3271	183	52	some	some	DET
fnp-3271	183	53	caution	caution	NOUN
fnp-3271	183	54	may	may	AUX
fnp-3271	183	55	be	be	AUX
fnp-3271	183	56	warranted	warrant	VERB
fnp-3271	183	57	for	for	ADP
fnp-3271	183	58	histologically	histologically	ADV
fnp-3271	183	59	low	low	ADJ
fnp-3271	183	60	-	-	PUNCT
fnp-3271	183	61	grade	grade	NOUN
fnp-3271	183	62	idh	idh	NOUN
fnp-3271	183	63	-	-	PUNCT
fnp-3271	183	64	wildtype	wildtype	NOUN
fnp-3271	183	65	diffuse	diffuse	NOUN
fnp-3271	183	66	astrocytic	astrocytic	ADJ
fnp-3271	183	67	tumors	tumor	NOUN
fnp-3271	183	68	with	with	ADP
fnp-3271	183	69	an	an	DET
fnp-3271	183	70	isolated	isolated	ADJ
fnp-3271	183	71	tert	tert	NOUN
fnp-3271	183	72	promoter	promoter	NOUN
fnp-3271	183	73	mutation	mutation	NOUN
fnp-3271	183	74	[	[	X
fnp-3271	183	75	32	32	NUM
fnp-3271	183	76	]	]	PUNCT
fnp-3271	183	77	.	.	PUNCT
fnp-3271	184	1	furthermore	furthermore	ADV
fnp-3271	184	2	,	,	PUNCT
fnp-3271	184	3	some	some	DET
fnp-3271	184	4	new	new	ADJ
fnp-3271	184	5	tumor	tumor	NOUN
fnp-3271	184	6	types	type	NOUN
fnp-3271	184	7	were	be	AUX
fnp-3271	184	8	recognized	recognize	VERB
fnp-3271	184	9	that	that	PRON
fnp-3271	184	10	will	will	AUX
fnp-3271	184	11	make	make	VERB
fnp-3271	184	12	it	it	PRON
fnp-3271	184	13	to	to	ADP
fnp-3271	184	14	the	the	DET
fnp-3271	184	15	new	new	ADJ
fnp-3271	184	16	who	who	PRON
fnp-3271	184	17	classification	classification	NOUN
fnp-3271	184	18	of	of	ADP
fnp-3271	184	19	cns	cns	PROPN
fnp-3271	184	20	tumors	tumor	NOUN
fnp-3271	184	21	(	(	PUNCT
fnp-3271	184	22	especially	especially	ADV
fnp-3271	184	23	diffuse	diffuse	VERB
fnp-3271	184	24	glioneuronal	glioneuronal	ADJ
fnp-3271	184	25	tumor	tumor	NOUN
fnp-3271	184	26	with	with	ADP
fnp-3271	184	27	oligodendroglioma	oligodendroglioma	ADJ
fnp-3271	184	28	-	-	PUNCT
fnp-3271	184	29	like	like	ADJ
fnp-3271	184	30	features	feature	NOUN
fnp-3271	184	31	and	and	CCONJ
fnp-3271	184	32	nuclear	nuclear	ADJ
fnp-3271	184	33	clusters	cluster	NOUN
fnp-3271	184	34	(	(	PUNCT
fnp-3271	184	35	dgonc	dgonc	PROPN
fnp-3271	184	36	)	)	PUNCT
fnp-3271	184	37	and	and	CCONJ
fnp-3271	184	38	desmoplastic	desmoplastic	ADJ
fnp-3271	184	39	myxoid	myxoid	ADJ
fnp-3271	184	40	tumor	tumor	NOUN
fnp-3271	184	41	of	of	ADP
fnp-3271	184	42	the	the	DET
fnp-3271	184	43	pineal	pineal	NOUN
fnp-3271	184	44	region	region	NOUN
fnp-3271	184	45	,	,	PUNCT
fnp-3271	184	46	smarcb1	smarcb1	NOUN
fnp-3271	184	47	-	-	PUNCT
fnp-3271	184	48	mutant	mutant	NOUN
fnp-3271	184	49	[	[	X
fnp-3271	184	50	33	33	NUM
fnp-3271	184	51	,	,	PUNCT
fnp-3271	184	52	34	34	NUM
fnp-3271	184	53	]	]	NUM
fnp-3271	184	54	)	)	PUNCT
fnp-3271	184	55	,	,	PUNCT
fnp-3271	184	56	and	and	CCONJ
fnp-3271	184	57	new	new	ADJ
fnp-3271	184	58	insights	insight	NOUN
fnp-3271	184	59	were	be	AUX
fnp-3271	184	60	obtained	obtain	VERB
fnp-3271	184	61	in	in	ADP
fnp-3271	184	62	areas	area	NOUN
fnp-3271	184	63	such	such	ADJ
fnp-3271	184	64	as	as	ADP
fnp-3271	184	65	the	the	DET
fnp-3271	184	66	oncogenesis	oncogenesis	NOUN
fnp-3271	184	67	of	of	ADP
fnp-3271	184	68	h3.3g34	h3.3g34	NOUN
fnp-3271	184	69	-	-	PUNCT
fnp-3271	184	70	mutant	mutant	ADJ
fnp-3271	184	71	gliomas	glioma	NOUN
fnp-3271	184	72	[	[	X
fnp-3271	184	73	35	35	NUM
fnp-3271	184	74	]	]	PUNCT
fnp-3271	184	75	,	,	PUNCT
fnp-3271	184	76	posterior	posterior	ADJ
fnp-3271	184	77	fossa	fossa	NOUN
fnp-3271	184	78	group	group	NOUN
fnp-3271	184	79	a	a	PRON
fnp-3271	184	80	(	(	PUNCT
fnp-3271	184	81	pfa	pfa	NOUN
fnp-3271	184	82	)	)	PUNCT
fnp-3271	184	83	ependymomas	ependymoma	VERB
fnp-3271	185	1	[	[	X
fnp-3271	185	2	36	36	NUM
fnp-3271	185	3	]	]	PUNCT
fnp-3271	185	4	,	,	PUNCT
fnp-3271	185	5	subependymal	subependymal	ADJ
fnp-3271	185	6	giant	giant	ADJ
fnp-3271	185	7	cell	cell	NOUN
fnp-3271	185	8	astrocytomas	astrocytoma	NOUN
fnp-3271	185	9	[	[	X
fnp-3271	185	10	37	37	NUM
fnp-3271	185	11	]	]	PUNCT
fnp-3271	185	12	,	,	PUNCT
fnp-3271	185	13	and	and	CCONJ
fnp-3271	185	14	in	in	ADP
fnp-3271	185	15	the	the	DET
fnp-3271	185	16	methylation	methylation	NOUN
fnp-3271	185	17	characteristics	characteristic	NOUN
fnp-3271	185	18	of	of	ADP
fnp-3271	185	19	germline	germline	NOUN
fnp-3271	185	20	-	-	PUNCT
fnp-3271	185	21	driven	drive	VERB
fnp-3271	185	22	replication	replication	NOUN
fnp-3271	185	23	repair	repair	NOUN
fnp-3271	185	24	-	-	PUNCT
fnp-3271	185	25	deficient	deficient	ADJ
fnp-3271	185	26	high	high	ADJ
fnp-3271	185	27	-	-	PUNCT
fnp-3271	185	28	grade	grade	NOUN
fnp-3271	185	29	gliomas	glioma	NOUN
fnp-3271	185	30	(	(	PUNCT
fnp-3271	185	31	‘	'	PUNCT
fnp-3271	185	32	unique	unique	ADJ
fnp-3271	185	33	hypomethylation	hypomethylation	NOUN
fnp-3271	185	34	patterns	pattern	NOUN
fnp-3271	185	35	’	'	PUNCT
fnp-3271	185	36	)	)	PUNCT
fnp-3271	186	1	[	[	X
fnp-3271	186	2	38	38	NUM
fnp-3271	186	3	]	]	PUNCT
fnp-3271	186	4	.	.	PUNCT
fnp-3271	187	1	very	very	ADV
fnp-3271	187	2	interesting	interesting	ADJ
fnp-3271	187	3	new	new	ADJ
fnp-3271	187	4	information	information	NOUN
fnp-3271	187	5	was	be	AUX
fnp-3271	187	6	published	publish	VERB
fnp-3271	187	7	on	on	ADP
fnp-3271	187	8	how	how	SCONJ
fnp-3271	187	9	glioblastomas	glioblastoma	NOUN
fnp-3271	187	10	interact	interact	VERB
fnp-3271	187	11	with	with	ADP
fnp-3271	187	12	neurons	neuron	NOUN
fnp-3271	187	13	[	[	X
fnp-3271	187	14	39	39	NUM
fnp-3271	187	15	]	]	PUNCT
fnp-3271	187	16	,	,	PUNCT
fnp-3271	187	17	and	and	CCONJ
fnp-3271	187	18	a	a	DET
fnp-3271	187	19	roadmap	roadmap	NOUN
fnp-3271	187	20	was	be	AUX
fnp-3271	187	21	presented	present	VERB
fnp-3271	187	22	for	for	ADP
fnp-3271	187	23	shaping	shape	VERB
fnp-3271	187	24	the	the	DET
fnp-3271	187	25	emerging	emerge	VERB
fnp-3271	187	26	field	field	NOUN
fnp-3271	187	27	of	of	ADP
fnp-3271	187	28	cancer	cancer	NOUN
fnp-3271	187	29	neuroscience	neuroscience	NOUN
fnp-3271	188	1	[	[	X
fnp-3271	188	2	40	40	NUM
fnp-3271	188	3	]	]	PUNCT
fnp-3271	188	4	.	.	PUNCT
fnp-3271	189	1	in	in	ADP
fnp-3271	189	2	depth	depth	NOUN
fnp-3271	189	3	(	(	PUNCT
fnp-3271	189	4	epi)genetic	epi)genetic	ADJ
fnp-3271	189	5	analysis	analysis	NOUN
fnp-3271	189	6	of	of	ADP
fnp-3271	189	7	single	single	ADJ
fnp-3271	189	8	(	(	PUNCT
fnp-3271	189	9	brain	brain	NOUN
fnp-3271	189	10	tumor	tumor	NOUN
fnp-3271	189	11	)	)	PUNCT
fnp-3271	189	12	cells	cell	NOUN
fnp-3271	189	13	is	be	AUX
fnp-3271	189	14	‘	'	PUNCT
fnp-3271	189	15	hot	hot	ADJ
fnp-3271	189	16	’	'	PUNCT
fnp-3271	189	17	nowadays	nowadays	ADV
fnp-3271	189	18	and	and	CCONJ
fnp-3271	189	19	indeed	indeed	ADV
fnp-3271	189	20	provides	provide	VERB
fnp-3271	189	21	an	an	DET
fnp-3271	189	22	enormous	enormous	ADJ
fnp-3271	189	23	amount	amount	NOUN
fnp-3271	189	24	of	of	ADP
fnp-3271	189	25	new	new	ADJ
fnp-3271	189	26	information	information	NOUN
fnp-3271	189	27	.	.	PUNCT
fnp-3271	190	1	a	a	DET
fnp-3271	190	2	novel	novel	ADJ
fnp-3271	190	3	tool	tool	NOUN
fnp-3271	190	4	for	for	ADP
fnp-3271	190	5	exploiting	exploit	VERB
fnp-3271	190	6	single	single	ADJ
fnp-3271	190	7	-	-	PUNCT
fnp-3271	190	8	cell	cell	NOUN
fnp-3271	190	9	rna	rna	NOUN
fnp-3271	190	10	sequencing	sequencing	NOUN
fnp-3271	190	11	data	datum	NOUN
fnp-3271	190	12	,	,	PUNCT
fnp-3271	190	13	the	the	DET
fnp-3271	190	14	single	single	ADJ
fnp-3271	190	15	-	-	PUNCT
fnp-3271	190	16	cell	cell	NOUN
fnp-3271	190	17	tumor	tumor	NOUN
fnp-3271	190	18	-	-	PUNCT
fnp-3271	190	19	host	host	NOUN
fnp-3271	190	20	interaction	interaction	NOUN
fnp-3271	190	21	tool	tool	NOUN
fnp-3271	190	22	(	(	PUNCT
fnp-3271	190	23	scthi	scthi	PROPN
fnp-3271	190	24	)	)	PUNCT
fnp-3271	190	25	,	,	PUNCT
fnp-3271	190	26	was	be	AUX
fnp-3271	190	27	published	publish	VERB
fnp-3271	190	28	in	in	ADP
fnp-3271	190	29	a	a	DET
fnp-3271	190	30	journal	journal	NOUN
fnp-3271	190	31	with	with	ADP
fnp-3271	190	32	the	the	DET
fnp-3271	190	33	impressive	impressive	ADJ
fnp-3271	190	34	name	name	NOUN
fnp-3271	190	35	gigascience	gigascience	NOUN
fnp-3271	190	36	[	[	X
fnp-3271	190	37	41	41	NUM
fnp-3271	190	38	]	]	PUNCT
fnp-3271	190	39	.	.	PUNCT
fnp-3271	191	1	although	although	SCONJ
fnp-3271	191	2	not	not	PART
fnp-3271	191	3	included	include	VERB
fnp-3271	191	4	in	in	ADP
fnp-3271	191	5	the	the	DET
fnp-3271	191	6	top	top	ADJ
fnp-3271	191	7	10	10	NUM
fnp-3271	191	8	list	list	NOUN
fnp-3271	191	9	in	in	ADP
fnp-3271	191	10	this	this	DET
fnp-3271	191	11	review	review	NOUN
fnp-3271	191	12	,	,	PUNCT
fnp-3271	191	13	much	much	ADJ
fnp-3271	191	14	has	have	AUX
fnp-3271	191	15	been	be	AUX
fnp-3271	191	16	discovered	discover	VERB
fnp-3271	191	17	in	in	ADP
fnp-3271	191	18	2020	2020	NUM
fnp-3271	191	19	about	about	ADP
fnp-3271	191	20	and	and	CCONJ
fnp-3271	191	21	because	because	SCONJ
fnp-3271	191	22	of	of	ADP
fnp-3271	191	23	the	the	DET
fnp-3271	191	24	covid-19	covid-19	PROPN
fnp-3271	191	25	pandemic	pandemic	NOUN
fnp-3271	191	26	,	,	PUNCT
fnp-3271	191	27	with	with	ADP
fnp-3271	191	28	some	some	DET
fnp-3271	191	29	consequences	consequence	NOUN
fnp-3271	191	30	for	for	ADP
fnp-3271	191	31	neurooncology	neurooncology	NOUN
fnp-3271	191	32	as	as	ADV
fnp-3271	191	33	well	well	ADV
fnp-3271	191	34	.	.	PUNCT
fnp-3271	192	1	because	because	SCONJ
fnp-3271	192	2	of	of	ADP
fnp-3271	192	3	the	the	DET
fnp-3271	192	4	very	very	ADV
fnp-3271	192	5	infectious	infectious	ADJ
fnp-3271	192	6	and	and	CCONJ
fnp-3271	192	7	often	often	ADV
fnp-3271	192	8	serious	serious	ADJ
fnp-3271	192	9	character	character	NOUN
fnp-3271	192	10	of	of	ADP
fnp-3271	192	11	the	the	DET
fnp-3271	192	12	disease	disease	NOUN
fnp-3271	192	13	,	,	PUNCT
fnp-3271	192	14	governments	government	NOUN
fnp-3271	192	15	had	have	VERB
fnp-3271	192	16	to	to	PART
fnp-3271	192	17	take	take	VERB
fnp-3271	192	18	drastic	drastic	ADJ
fnp-3271	192	19	actions	action	NOUN
fnp-3271	192	20	such	such	ADJ
fnp-3271	192	21	as	as	ADP
fnp-3271	192	22	enforcing	enforce	VERB
fnp-3271	192	23	the	the	DET
fnp-3271	192	24	wearing	wearing	NOUN
fnp-3271	192	25	of	of	ADP
fnp-3271	192	26	face	face	NOUN
fnp-3271	192	27	masks	mask	NOUN
fnp-3271	192	28	,	,	PUNCT
fnp-3271	192	29	installing	instal	VERB
fnp-3271	192	30	social	social	ADJ
fnp-3271	192	31	distancing	distancing	NOUN
fnp-3271	192	32	measures	measure	NOUN
fnp-3271	192	33	and	and	CCONJ
fnp-3271	192	34	limiting	limit	VERB
fnp-3271	192	35	the	the	DET
fnp-3271	192	36	free	free	ADJ
fnp-3271	192	37	movement	movement	NOUN
fnp-3271	192	38	of	of	ADP
fnp-3271	192	39	citizens	citizen	NOUN
fnp-3271	192	40	.	.	PUNCT
fnp-3271	193	1	combined	combine	VERB
fnp-3271	193	2	with	with	ADP
fnp-3271	193	3	the	the	DET
fnp-3271	193	4	finding	finding	NOUN
fnp-3271	193	5	that	that	SCONJ
fnp-3271	193	6	cancer	cancer	NOUN
fnp-3271	193	7	patients	patient	NOUN
fnp-3271	193	8	have	have	AUX
fnp-3271	193	9	an	an	DET
fnp-3271	193	10	increased	increase	VERB
fnp-3271	193	11	risk	risk	NOUN
fnp-3271	193	12	of	of	ADP
fnp-3271	193	13	dying	die	VERB
fnp-3271	193	14	because	because	SCONJ
fnp-3271	193	15	of	of	ADP
fnp-3271	193	16	covid-19	covid-19	PROPN
fnp-3271	193	17	infection	infection	NOUN
fnp-3271	193	18	,	,	PUNCT
fnp-3271	193	19	this	this	PRON
fnp-3271	193	20	has	have	AUX
fnp-3271	193	21	caused	cause	VERB
fnp-3271	193	22	increased	increase	VERB
fnp-3271	193	23	stress	stress	NOUN
fnp-3271	193	24	and	and	CCONJ
fnp-3271	193	25	anxiety	anxiety	NOUN
fnp-3271	193	26	amongst	amongst	ADP
fnp-3271	193	27	brain	brain	NOUN
fnp-3271	193	28	tumor	tumor	NOUN
fnp-3271	193	29	patients	patient	NOUN
fnp-3271	193	30	and	and	CCONJ
fnp-3271	193	31	their	their	PRON
fnp-3271	193	32	caregivers	caregiver	NOUN
fnp-3271	193	33	[	[	X
fnp-3271	193	34	42	42	NUM
fnp-3271	193	35	,	,	PUNCT
fnp-3271	193	36	43	43	NUM
fnp-3271	193	37	]	]	PUNCT
fnp-3271	193	38	.	.	PUNCT
fnp-3271	194	1	neurooncologic	neurooncologic	PROPN
fnp-3271	194	2	care	care	PROPN
fnp-3271	194	3	needed	need	VERB
fnp-3271	194	4	to	to	PART
fnp-3271	194	5	be	be	AUX
fnp-3271	194	6	delivered	deliver	VERB
fnp-3271	194	7	in	in	ADP
fnp-3271	194	8	an	an	DET
fnp-3271	194	9	adapted	adapted	ADJ
fnp-3271	194	10	form	form	NOUN
fnp-3271	194	11	,	,	PUNCT
fnp-3271	194	12	minimizing	minimize	VERB
fnp-3271	194	13	exposures	exposure	NOUN
fnp-3271	194	14	for	for	ADP
fnp-3271	194	15	patients	patient	NOUN
fnp-3271	194	16	and	and	CCONJ
fnp-3271	194	17	addressing	address	VERB
fnp-3271	194	18	risks	risk	NOUN
fnp-3271	194	19	and	and	CCONJ
fnp-3271	194	20	benefits	benefit	NOUN
fnp-3271	194	21	of	of	ADP
fnp-3271	194	22	all	all	DET
fnp-3271	194	23	therapeutic	therapeutic	ADJ
fnp-3271	194	24	interventions	intervention	NOUN
fnp-3271	194	25	,	,	PUNCT
fnp-3271	194	26	while	while	SCONJ
fnp-3271	194	27	at	at	ADP
fnp-3271	194	28	the	the	DET
fnp-3271	194	29	same	same	ADJ
fnp-3271	194	30	time	time	NOUN
fnp-3271	194	31	ensuring	ensure	VERB
fnp-3271	194	32	the	the	DET
fnp-3271	194	33	health	health	NOUN
fnp-3271	194	34	of	of	ADP
fnp-3271	194	35	the	the	DET
fnp-3271	194	36	multi	multi	ADJ
fnp-3271	194	37	-	-	ADJ
fnp-3271	194	38	disciplinary	disciplinary	ADJ
fnp-3271	194	39	neurooncology	neurooncology	NOUN
fnp-3271	194	40	workforce	workforce	NOUN
fnp-3271	194	41	as	as	ADV
fnp-3271	194	42	much	much	ADV
fnp-3271	194	43	as	as	ADP
fnp-3271	194	44	possible	possible	ADJ
fnp-3271	194	45	[	[	X
fnp-3271	194	46	44	44	NUM
fnp-3271	194	47	]	]	PUNCT
fnp-3271	194	48	.	.	PUNCT
fnp-3271	195	1	interestingly	interestingly	ADV
fnp-3271	195	2	,	,	PUNCT
fnp-3271	195	3	it	it	PRON
fnp-3271	195	4	appeared	appear	VERB
fnp-3271	195	5	that	that	SCONJ
fnp-3271	195	6	some	some	DET
fnp-3271	195	7	diagnostic	diagnostic	ADJ
fnp-3271	195	8	(	(	PUNCT
fnp-3271	195	9	neuro)pathology	neuro)pathology	NOUN
fnp-3271	195	10	services	service	NOUN
fnp-3271	195	11	can	can	AUX
fnp-3271	195	12	be	be	AUX
fnp-3271	195	13	reliably	reliably	ADV
fnp-3271	195	14	provided	provide	VERB
fnp-3271	195	15	while	while	SCONJ
fnp-3271	195	16	working	work	VERB
fnp-3271	195	17	from	from	ADP
fnp-3271	195	18	home	home	NOUN
fnp-3271	195	19	when	when	SCONJ
fnp-3271	195	20	using	use	VERB
fnp-3271	195	21	platforms	platform	NOUN
fnp-3271	195	22	for	for	ADP
fnp-3271	195	23	whole	whole	ADJ
fnp-3271	195	24	slide	slide	NOUN
fnp-3271	195	25	images	image	NOUN
fnp-3271	195	26	(	(	PUNCT
fnp-3271	195	27	wsis	wsis	NOUN
fnp-3271	195	28	)	)	PUNCT
fnp-3271	195	29	.	.	PUNCT
fnp-3271	196	1	of	of	ADP
fnp-3271	196	2	course	course	ADV
fnp-3271	196	3	,	,	PUNCT
fnp-3271	196	4	some	some	DET
fnp-3271	196	5	activities	activity	NOUN
fnp-3271	196	6	(	(	PUNCT
fnp-3271	196	7	e.g.	e.g.	ADV
fnp-3271	196	8	tissue	tissue	NOUN
fnp-3271	196	9	sampling	sampling	NOUN
fnp-3271	196	10	,	,	PUNCT
fnp-3271	196	11	processing	processing	NOUN
fnp-3271	196	12	,	,	PUNCT
fnp-3271	196	13	cutting	cutting	NOUN
fnp-3271	196	14	,	,	PUNCT
fnp-3271	196	15	staining	stain	VERB
fnp-3271	196	16	,	,	PUNCT
fnp-3271	196	17	molecular	molecular	ADJ
fnp-3271	196	18	analyses	analysis	NOUN
fnp-3271	196	19	)	)	PUNCT
fnp-3271	196	20	still	still	ADV
fnp-3271	196	21	need	need	VERB
fnp-3271	196	22	to	to	PART
fnp-3271	196	23	be	be	AUX
fnp-3271	196	24	done	do	VERB
fnp-3271	196	25	in	in	ADP
fnp-3271	196	26	the	the	DET
fnp-3271	196	27	institutes	institutes	NOUN
fnp-3271	196	28	[	[	X
fnp-3271	196	29	45	45	NUM
fnp-3271	196	30	-	-	SYM
fnp-3271	196	31	47	47	NUM
fnp-3271	196	32	]	]	PUNCT
fnp-3271	196	33	.	.	PUNCT
fnp-3271	197	1	as	as	ADP
fnp-3271	197	2	an	an	DET
fnp-3271	197	3	emergency	emergency	NOUN
fnp-3271	197	4	response	response	NOUN
fnp-3271	197	5	to	to	ADP
fnp-3271	197	6	the	the	DET
fnp-3271	197	7	pandemic	pandemic	NOUN
fnp-3271	197	8	,	,	PUNCT
fnp-3271	197	9	the	the	DET
fnp-3271	197	10	uk	uk	PROPN
fnp-3271	197	11	royal	royal	PROPN
fnp-3271	197	12	college	college	PROPN
fnp-3271	197	13	of	of	ADP
fnp-3271	197	14	pathologists	pathologist	NOUN
fnp-3271	197	15	provided	provide	VERB
fnp-3271	197	16	guidance	guidance	NOUN
fnp-3271	197	17	for	for	ADP
fnp-3271	197	18	remote	remote	ADJ
fnp-3271	197	19	reporting	reporting	NOUN
fnp-3271	197	20	of	of	ADP
fnp-3271	197	21	digital	digital	ADJ
fnp-3271	197	22	pathology	pathology	NOUN
fnp-3271	197	23	slides	slide	NOUN
fnp-3271	197	24	and	and	CCONJ
fnp-3271	197	25	the	the	DET
fnp-3271	197	26	us	us	PROPN
fnp-3271	197	27	food	food	NOUN
fnp-3271	197	28	and	and	CCONJ
fnp-3271	197	29	drug	drug	PROPN
fnp-3271	197	30	administration	administration	PROPN
fnp-3271	197	31	(	(	PUNCT
fnp-3271	197	32	fda	fda	PROPN
fnp-3271	197	33	)	)	PUNCT
fnp-3271	197	34	granted	grant	VERB
fnp-3271	197	35	a	a	DET
fnp-3271	197	36	waiver	waiver	NOUN
fnp-3271	197	37	for	for	ADP
fnp-3271	197	38	the	the	DET
fnp-3271	197	39	use	use	NOUN
fnp-3271	197	40	of	of	ADP
fnp-3271	197	41	readily	readily	ADV
fnp-3271	197	42	available	available	ADJ
fnp-3271	197	43	consumer	consumer	NOUN
fnp-3271	197	44	monitors	monitor	NOUN
fnp-3271	197	45	at	at	ADP
fnp-3271	197	46	home	home	NOUN
fnp-3271	197	47	[	[	X
fnp-3271	197	48	48	48	NUM
fnp-3271	197	49	,	,	PUNCT
fnp-3271	197	50	49	49	NUM
fnp-3271	197	51	]	]	PUNCT
fnp-3271	197	52	.	.	PUNCT
fnp-3271	198	1	furthermore	furthermore	ADV
fnp-3271	198	2	,	,	PUNCT
fnp-3271	198	3	the	the	DET
fnp-3271	198	4	covid-19	covid-19	PROPN
fnp-3271	198	5	pandemic	pandemic	NOUN
fnp-3271	198	6	has	have	AUX
fnp-3271	198	7	boosted	boost	VERB
fnp-3271	198	8	the	the	DET
fnp-3271	198	9	exploitation	exploitation	NOUN
fnp-3271	198	10	of	of	ADP
fnp-3271	198	11	present	present	ADJ
fnp-3271	198	12	-	-	PUNCT
fnp-3271	198	13	day	day	NOUN
fnp-3271	198	14	technology	technology	NOUN
fnp-3271	198	15	for	for	ADP
fnp-3271	198	16	teaching	teaching	NOUN
fnp-3271	198	17	of	of	ADP
fnp-3271	198	18	medical	medical	ADJ
fnp-3271	198	19	students	student	NOUN
fnp-3271	198	20	and	and	CCONJ
fnp-3271	198	21	pathology	pathology	NOUN
fnp-3271	198	22	residents	resident	NOUN
fnp-3271	198	23	(	(	PUNCT
fnp-3271	198	24	e.g.	e.g.	ADV
fnp-3271	198	25	using	use	VERB
fnp-3271	198	26	digital	digital	ADJ
fnp-3271	198	27	lectures	lecture	NOUN
fnp-3271	198	28	,	,	PUNCT
fnp-3271	198	29	videoconferencing	videoconferencing	NOUN
fnp-3271	198	30	,	,	PUNCT
fnp-3271	198	31	and	and	CCONJ
fnp-3271	198	32	online	online	ADJ
fnp-3271	198	33	resources	resource	NOUN
fnp-3271	198	34	utilizing	utilize	VERB
fnp-3271	198	35	collections	collection	NOUN
fnp-3271	198	36	of	of	ADP
fnp-3271	198	37	wsis	wsis	NOUN
fnp-3271	198	38	)	)	PUNCT
fnp-3271	199	1	[	[	X
fnp-3271	199	2	50	50	NUM
fnp-3271	199	3	,	,	PUNCT
fnp-3271	199	4	51	51	NUM
fnp-3271	199	5	]	]	PUNCT
fnp-3271	199	6	and	and	CCONJ
fnp-3271	199	7	has	have	AUX
fnp-3271	199	8	drastically	drastically	ADV
fnp-3271	199	9	changed	change	VERB
fnp-3271	199	10	the	the	DET
fnp-3271	199	11	way	way	NOUN
fnp-3271	199	12	scientific	scientific	ADJ
fnp-3271	199	13	communities	community	NOUN
fnp-3271	199	14	interact	interact	VERB
fnp-3271	199	15	now	now	ADV
fnp-3271	199	16	that	that	SCONJ
fnp-3271	199	17	meetings	meeting	NOUN
fnp-3271	199	18	can	can	AUX
fnp-3271	199	19	not	not	PART
fnp-3271	199	20	be	be	AUX
fnp-3271	199	21	organized	organize	VERB
fnp-3271	199	22	in	in	ADP
fnp-3271	199	23	their	their	PRON
fnp-3271	199	24	traditional	traditional	ADJ
fnp-3271	199	25	format	format	NOUN
fnp-3271	199	26	.	.	PUNCT
fnp-3271	200	1	however	however	ADV
fnp-3271	200	2	,	,	PUNCT
fnp-3271	200	3	the	the	DET
fnp-3271	200	4	‘	'	PUNCT
fnp-3271	200	5	human	human	ADJ
fnp-3271	200	6	touch	touch	NOUN
fnp-3271	200	7	’	'	PUNCT
fnp-3271	200	8	is	be	AUX
fnp-3271	200	9	easily	easily	ADV
fnp-3271	200	10	missed	miss	VERB
fnp-3271	200	11	in	in	ADP
fnp-3271	200	12	such	such	ADJ
fnp-3271	200	13	virtual	virtual	ADJ
fnp-3271	200	14	encounters	encounter	NOUN
fnp-3271	200	15	.	.	PUNCT
fnp-3271	201	1	finding	find	VERB
fnp-3271	201	2	the	the	DET
fnp-3271	201	3	right	right	ADJ
fnp-3271	201	4	balance	balance	NOUN
fnp-3271	201	5	between	between	ADP
fnp-3271	201	6	attending	attend	VERB
fnp-3271	201	7	web	web	NOUN
fnp-3271	201	8	-	-	PUNCT
fnp-3271	201	9	based	base	VERB
fnp-3271	201	10	meetings	meeting	NOUN
fnp-3271	201	11	,	,	PUNCT
fnp-3271	201	12	getting	get	VERB
fnp-3271	201	13	(	(	PUNCT
fnp-3271	201	14	the	the	DET
fnp-3271	201	15	rest	rest	NOUN
fnp-3271	201	16	of	of	ADP
fnp-3271	201	17	)	)	PUNCT
fnp-3271	201	18	our	our	PRON
fnp-3271	201	19	daily	daily	ADJ
fnp-3271	201	20	job	job	NOUN
fnp-3271	201	21	done	do	VERB
fnp-3271	201	22	from	from	ADP
fnp-3271	201	23	home	home	NOUN
fnp-3271	201	24	,	,	PUNCT
fnp-3271	201	25	and	and	CCONJ
fnp-3271	201	26	maintaining	maintain	VERB
fnp-3271	201	27	a	a	DET
fnp-3271	201	28	healthy	healthy	ADJ
fnp-3271	201	29	personal	personal	ADJ
fnp-3271	201	30	life	life	NOUN
fnp-3271	201	31	can	can	AUX
fnp-3271	201	32	be	be	AUX
fnp-3271	201	33	challenging	challenge	VERB
fnp-3271	201	34	[	[	PUNCT
fnp-3271	201	35	52	52	NUM
fnp-3271	201	36	]	]	PUNCT
fnp-3271	201	37	.	.	PUNCT
fnp-3271	202	1	also	also	ADV
fnp-3271	202	2	,	,	PUNCT
fnp-3271	202	3	it	it	PRON
fnp-3271	202	4	remains	remain	VERB
fnp-3271	202	5	to	to	PART
fnp-3271	202	6	be	be	AUX
fnp-3271	202	7	seen	see	VERB
fnp-3271	202	8	what	what	PRON
fnp-3271	202	9	the	the	DET
fnp-3271	202	10	long	long	ADJ
fnp-3271	202	11	-	-	PUNCT
fnp-3271	202	12	term	term	NOUN
fnp-3271	202	13	impact	impact	NOUN
fnp-3271	202	14	of	of	ADP
fnp-3271	202	15	the	the	DET
fnp-3271	202	16	pandemic	pandemic	NOUN
fnp-3271	202	17	is	be	AUX
fnp-3271	202	18	on	on	ADP
fnp-3271	202	19	cancer	cancer	NOUN
fnp-3271	202	20	research	research	NOUN
fnp-3271	203	1	[	[	X
fnp-3271	203	2	53	53	NUM
fnp-3271	203	3	]	]	PUNCT
fnp-3271	203	4	.	.	PUNCT
fnp-3271	204	1	last	last	ADJ
fnp-3271	204	2	but	but	CCONJ
fnp-3271	204	3	not	not	PART
fnp-3271	204	4	least	least	ADJ
fnp-3271	204	5	,	,	PUNCT
fnp-3271	204	6	ignorance	ignorance	NOUN
fnp-3271	204	7	of	of	ADP
fnp-3271	204	8	one	one	NUM
fnp-3271	204	9	’s	’s	PART
fnp-3271	204	10	own	own	ADJ
fnp-3271	204	11	ignorance	ignorance	NOUN
fnp-3271	204	12	is	be	AUX
fnp-3271	204	13	worrisome	worrisome	ADJ
fnp-3271	204	14	,	,	PUNCT
fnp-3271	204	15	especially	especially	ADV
fnp-3271	204	16	so	so	ADV
fnp-3271	204	17	because	because	SCONJ
fnp-3271	204	18	not	not	PART
fnp-3271	204	19	infrequently	infrequently	ADV
fnp-3271	204	20	it	it	PRON
fnp-3271	204	21	is	be	AUX
fnp-3271	204	22	combined	combine	VERB
fnp-3271	204	23	with	with	ADP
fnp-3271	204	24	overconfidence	overconfidence	NOUN
fnp-3271	204	25	,	,	PUNCT
fnp-3271	205	1	a	a	DET
fnp-3271	205	2	phenomenon	phenomenon	NOUN
fnp-3271	205	3	called	call	VERB
fnp-3271	205	4	the	the	DET
fnp-3271	205	5	dunning	dun	VERB
fnp-3271	205	6	-	-	PUNCT
fnp-3271	205	7	kruger	kruger	NOUN
fnp-3271	205	8	effect	effect	NOUN
fnp-3271	205	9	[	[	X
fnp-3271	205	10	54	54	NUM
fnp-3271	205	11	]	]	PUNCT
fnp-3271	205	12	.	.	PUNCT
fnp-3271	205	13	improving	improve	VERB
fnp-3271	205	14	skills	skill	NOUN
fnp-3271	205	15	and	and	CCONJ
fnp-3271	205	16	metacognitive	metacognitive	ADJ
fnp-3271	205	17	competence	competence	NOUN
fnp-3271	205	18	helps	help	VERB
fnp-3271	205	19	one	one	NUM
fnp-3271	205	20	to	to	PART
fnp-3271	205	21	move	move	VERB
fnp-3271	205	22	on	on	ADP
fnp-3271	205	23	from	from	ADP
fnp-3271	205	24	conscious	conscious	ADJ
fnp-3271	205	25	incompetence	incompetence	NOUN
fnp-3271	205	26	to	to	ADP
fnp-3271	205	27	a	a	DET
fnp-3271	205	28	phase	phase	NOUN
fnp-3271	205	29	of	of	ADP
fnp-3271	205	30	conscious	conscious	ADJ
fnp-3271	205	31	competence	competence	NOUN
fnp-3271	205	32	that	that	PRON
fnp-3271	205	33	is	be	AUX
fnp-3271	205	34	more	more	ADV
fnp-3271	205	35	in	in	ADP
fnp-3271	205	36	balance	balance	NOUN
fnp-3271	205	37	with	with	ADP
fnp-3271	205	38	the	the	DET
fnp-3271	205	39	level	level	NOUN
fnp-3271	205	40	of	of	ADP
fnp-3271	205	41	confidence	confidence	NOUN
fnp-3271	205	42	(	(	PUNCT
fnp-3271	205	43	figure	figure	NOUN
fnp-3271	205	44	3	3	NUM
fnp-3271	205	45	)	)	PUNCT
fnp-3271	205	46	.	.	PUNCT
fnp-3271	206	1	although	although	SCONJ
fnp-3271	206	2	a	a	DET
fnp-3271	206	3	review	review	NOUN
fnp-3271	206	4	like	like	ADP
fnp-3271	206	5	this	this	PRON
fnp-3271	206	6	only	only	ADV
fnp-3271	206	7	allows	allow	VERB
fnp-3271	206	8	for	for	ADP
fnp-3271	206	9	‘	'	PUNCT
fnp-3271	206	10	scratching	scratch	VERB
fnp-3271	206	11	the	the	DET
fnp-3271	206	12	surface	surface	NOUN
fnp-3271	206	13	’	'	PUNCT
fnp-3271	206	14	of	of	ADP
fnp-3271	206	15	the	the	DET
fnp-3271	206	16	selected	select	VERB
fnp-3271	206	17	discoveries	discovery	NOUN
fnp-3271	206	18	,	,	PUNCT
fnp-3271	206	19	it	it	PRON
fnp-3271	206	20	hopefully	hopefully	ADV
fnp-3271	206	21	does	do	AUX
fnp-3271	206	22	help	help	VERB
fnp-3271	206	23	one	one	NOUN
fnp-3271	206	24	to	to	PART
fnp-3271	206	25	move	move	VERB
fnp-3271	206	26	further	far	ADV
fnp-3271	206	27	away	away	ADV
fnp-3271	206	28	from	from	ADP
fnp-3271	206	29	unconscious	unconscious	ADJ
fnp-3271	206	30	incompetence	incompetence	NOUN
fnp-3271	206	31	,	,	PUNCT
fnp-3271	206	32	especially	especially	ADV
fnp-3271	206	33	so	so	ADV
fnp-3271	206	34	if	if	SCONJ
fnp-3271	206	35	the	the	DET
fnp-3271	206	36	review	review	NOUN
fnp-3271	206	37	indeed	indeed	ADV
fnp-3271	206	38	works	work	VERB
fnp-3271	206	39	as	as	ADP
fnp-3271	206	40	an	an	DET
fnp-3271	206	41	incentive	incentive	NOUN
fnp-3271	206	42	to	to	PART
fnp-3271	206	43	read	read	VERB
fnp-3271	206	44	and	and	CCONJ
fnp-3271	206	45	appreciate	appreciate	VERB
fnp-3271	206	46	the	the	DET
fnp-3271	206	47	original	original	ADJ
fnp-3271	206	48	papers	paper	NOUN
fnp-3271	206	49	that	that	PRON
fnp-3271	206	50	were	be	AUX
fnp-3271	206	51	used	use	VERB
fnp-3271	206	52	as	as	ADP
fnp-3271	206	53	building	build	VERB
fnp-3271	206	54	blocks	block	NOUN
fnp-3271	206	55	for	for	ADP
fnp-3271	206	56	the	the	DET
fnp-3271	206	57	present	present	ADJ
fnp-3271	206	58	manuscript	manuscript	NOUN
fnp-3271	206	59	.	.	PUNCT
fnp-3271	207	1	fig	fig	NOUN
fnp-3271	207	2	.	.	PUNCT
fnp-3271	208	1	3	3	X
fnp-3271	208	2	.	.	X
fnp-3271	208	3	the	the	DET
fnp-3271	208	4	dunning	dun	VERB
fnp-3271	208	5	-	-	PUNCT
fnp-3271	208	6	kruger	kruger	NOUN
fnp-3271	208	7	effect	effect	NOUN
fnp-3271	208	8	:	:	PUNCT
fnp-3271	208	9	a	a	DET
fnp-3271	208	10	remarkable	remarkable	ADJ
fnp-3271	208	11	relationship	relationship	NOUN
fnp-3271	208	12	between	between	ADP
fnp-3271	208	13	competence	competence	NOUN
fnp-3271	208	14	and	and	CCONJ
fnp-3271	208	15	confidence	confidence	NOUN
fnp-3271	208	16	.	.	PUNCT
fnp-3271	209	1	in	in	ADP
fnp-3271	209	2	1999	1999	NUM
fnp-3271	209	3	,	,	PUNCT
fnp-3271	209	4	david	david	PROPN
fnp-3271	209	5	dunning	dunning	NOUN
fnp-3271	209	6	and	and	CCONJ
fnp-3271	209	7	justin	justin	PROPN
fnp-3271	209	8	kruger	kruger	PROPN
fnp-3271	209	9	described	describe	VERB
fnp-3271	209	10	the	the	DET
fnp-3271	209	11	phenomenon	phenomenon	NOUN
fnp-3271	209	12	that	that	SCONJ
fnp-3271	209	13	people	people	NOUN
fnp-3271	209	14	tend	tend	VERB
fnp-3271	209	15	to	to	PART
fnp-3271	209	16	initially	initially	ADV
fnp-3271	209	17	hold	hold	VERB
fnp-3271	209	18	overly	overly	ADV
fnp-3271	209	19	favorable	favorable	ADJ
fnp-3271	209	20	views	view	NOUN
fnp-3271	209	21	of	of	ADP
fnp-3271	209	22	their	their	PRON
fnp-3271	209	23	abilities	ability	NOUN
fnp-3271	209	24	in	in	ADP
fnp-3271	209	25	many	many	ADJ
fnp-3271	209	26	social	social	ADJ
fnp-3271	209	27	and	and	CCONJ
fnp-3271	209	28	intellectual	intellectual	ADJ
fnp-3271	209	29	domains	domain	NOUN
fnp-3271	209	30	[	[	X
fnp-3271	209	31	54	54	NUM
fnp-3271	209	32	]	]	PUNCT
fnp-3271	209	33	.	.	PUNCT
fnp-3271	210	1	indeed	indeed	ADV
fnp-3271	210	2	,	,	PUNCT
fnp-3271	210	3	people	people	NOUN
fnp-3271	210	4	not	not	PART
fnp-3271	210	5	infrequently	infrequently	ADV
fnp-3271	210	6	share	share	VERB
fnp-3271	210	7	strong	strong	ADJ
fnp-3271	210	8	opinions	opinion	NOUN
fnp-3271	210	9	on	on	ADP
fnp-3271	210	10	particular	particular	ADJ
fnp-3271	210	11	topics	topic	NOUN
fnp-3271	210	12	without	without	ADP
fnp-3271	210	13	being	be	AUX
fnp-3271	210	14	hindered	hinder	VERB
fnp-3271	210	15	by	by	ADP
fnp-3271	210	16	their	their	PRON
fnp-3271	210	17	lack	lack	NOUN
fnp-3271	210	18	of	of	ADP
fnp-3271	210	19	competence	competence	NOUN
fnp-3271	210	20	(	(	PUNCT
fnp-3271	210	21	in	in	ADP
fnp-3271	210	22	other	other	ADJ
fnp-3271	210	23	words	word	NOUN
fnp-3271	210	24	,	,	PUNCT
fnp-3271	210	25	they	they	PRON
fnp-3271	210	26	’re	’re	VERB
fnp-3271	210	27	on	on	ADP
fnp-3271	210	28	top	top	NOUN
fnp-3271	210	29	of	of	ADP
fnp-3271	210	30	‘	'	PUNCT
fnp-3271	210	31	mount	mount	ADJ
fnp-3271	210	32	stupid	stupid	NOUN
fnp-3271	210	33	’	'	PUNCT
fnp-3271	210	34	without	without	ADP
fnp-3271	210	35	knowing	know	VERB
fnp-3271	210	36	it	it	PRON
fnp-3271	210	37	)	)	PUNCT
fnp-3271	210	38	.	.	PUNCT
fnp-3271	211	1	improving	improve	VERB
fnp-3271	211	2	skills	skill	NOUN
fnp-3271	211	3	and	and	CCONJ
fnp-3271	211	4	metacognitive	metacognitive	ADJ
fnp-3271	211	5	competence	competence	NOUN
fnp-3271	211	6	helps	help	VERB
fnp-3271	211	7	to	to	PART
fnp-3271	211	8	move	move	VERB
fnp-3271	211	9	on	on	ADP
fnp-3271	211	10	via	via	ADP
fnp-3271	211	11	the	the	DET
fnp-3271	211	12	‘	'	PUNCT
fnp-3271	211	13	valley	valley	NOUN
fnp-3271	211	14	of	of	ADP
fnp-3271	211	15	despair	despair	NOUN
fnp-3271	211	16	’	'	PUNCT
fnp-3271	211	17	(	(	PUNCT
fnp-3271	211	18	conscious	conscious	ADJ
fnp-3271	211	19	incompetence	incompetence	NOUN
fnp-3271	211	20	:	:	PUNCT
fnp-3271	211	21	knowing	know	VERB
fnp-3271	211	22	that	that	SCONJ
fnp-3271	211	23	you	you	PRON
fnp-3271	211	24	only	only	ADV
fnp-3271	211	25	have	have	VERB
fnp-3271	211	26	very	very	ADV
fnp-3271	211	27	limited	limited	ADJ
fnp-3271	211	28	knowledge	knowledge	NOUN
fnp-3271	211	29	and/or	and/or	CCONJ
fnp-3271	211	30	understanding	understanding	NOUN
fnp-3271	211	31	of	of	ADP
fnp-3271	211	32	a	a	DET
fnp-3271	211	33	particular	particular	ADJ
fnp-3271	211	34	topic	topic	NOUN
fnp-3271	211	35	)	)	PUNCT
fnp-3271	211	36	to	to	ADP
fnp-3271	211	37	the	the	DET
fnp-3271	211	38	‘	'	PUNCT
fnp-3271	211	39	slope	slope	NOUN
fnp-3271	211	40	of	of	ADP
fnp-3271	211	41	enlightenment	enlightenment	PROPN
fnp-3271	211	42	’	'	PUNCT
fnp-3271	211	43	,	,	PUNCT
fnp-3271	211	44	where	where	SCONJ
fnp-3271	211	45	competence	competence	NOUN
fnp-3271	211	46	and	and	CCONJ
fnp-3271	211	47	confidence	confidence	NOUN
fnp-3271	211	48	are	be	AUX
fnp-3271	211	49	more	more	ADJ
fnp-3271	211	50	in	in	ADP
fnp-3271	211	51	balance	balance	NOUN
fnp-3271	211	52	.	.	PUNCT
fnp-3271	212	1	acknowledging	acknowledge	VERB
fnp-3271	212	2	that	that	SCONJ
fnp-3271	212	3	competence	competence	NOUN
fnp-3271	212	4	is	be	AUX
fnp-3271	212	5	often	often	ADV
fnp-3271	212	6	a	a	DET
fnp-3271	212	7	matter	matter	NOUN
fnp-3271	212	8	of	of	ADP
fnp-3271	212	9	continuing	continue	VERB
fnp-3271	212	10	education	education	NOUN
fnp-3271	212	11	and	and	CCONJ
fnp-3271	212	12	professional	professional	ADJ
fnp-3271	212	13	development	development	NOUN
fnp-3271	212	14	,	,	PUNCT
fnp-3271	212	15	i	i	PRON
fnp-3271	212	16	doubt	doubt	VERB
fnp-3271	212	17	if	if	SCONJ
fnp-3271	212	18	the	the	DET
fnp-3271	212	19	ultimate	ultimate	ADJ
fnp-3271	212	20	goal	goal	NOUN
fnp-3271	212	21	in	in	ADP
fnp-3271	212	22	medicine	medicine	NOUN
fnp-3271	212	23	is	be	AUX
fnp-3271	212	24	really	really	ADV
fnp-3271	212	25	to	to	PART
fnp-3271	212	26	strive	strive	VERB
fnp-3271	212	27	for	for	ADP
fnp-3271	212	28	the	the	DET
fnp-3271	212	29	level	level	NOUN
fnp-3271	212	30	of	of	ADP
fnp-3271	212	31	unconscious	unconscious	ADJ
fnp-3271	212	32	competence	competence	NOUN
fnp-3271	212	33	(	(	PUNCT
fnp-3271	212	34	hence	hence	ADV
fnp-3271	212	35	the	the	DET
fnp-3271	212	36	question	question	NOUN
fnp-3271	212	37	mark	mark	NOUN
fnp-3271	212	38	behind	behind	ADP
fnp-3271	212	39	that	that	DET
fnp-3271	212	40	term	term	NOUN
fnp-3271	212	41	)	)	PUNCT
fnp-3271	212	42	.	.	PUNCT
fnp-3271	213	1	meanwhile	meanwhile	ADV
fnp-3271	213	2	,	,	PUNCT
fnp-3271	213	3	this	this	DET
fnp-3271	213	4	review	review	NOUN
fnp-3271	213	5	hopefully	hopefully	ADV
fnp-3271	213	6	helps	help	VERB
fnp-3271	213	7	to	to	PART
fnp-3271	213	8	climb	climb	VERB
fnp-3271	213	9	the	the	DET
fnp-3271	213	10	‘	'	PUNCT
fnp-3271	213	11	slope	slope	NOUN
fnp-3271	213	12	of	of	ADP
fnp-3271	213	13	enlightenment	enlightenment	NOUN
fnp-3271	213	14	’	'	PUNCT
fnp-3271	213	15	somewhat	somewhat	ADV
fnp-3271	213	16	further	far	ADV
fnp-3271	213	17	.	.	PUNCT
fnp-3271	214	1	references	reference	NOUN
fnp-3271	214	2	1	1	NUM
fnp-3271	214	3	.	.	PUNCT
fnp-3271	214	4	banan	banan	PROPN
fnp-3271	214	5	,	,	PUNCT
fnp-3271	214	6	r.	r.	PROPN
fnp-3271	214	7	,	,	PUNCT
fnp-3271	214	8	et	et	PROPN
fnp-3271	214	9	al	al	PROPN
fnp-3271	214	10	.	.	PROPN
fnp-3271	214	11	,	,	PUNCT
fnp-3271	214	12	infratentorial	infratentorial	ADJ
fnp-3271	214	13	idh	idh	NOUN
fnp-3271	214	14	-	-	PUNCT
fnp-3271	214	15	mutant	mutant	NOUN
fnp-3271	214	16	astrocytoma	astrocytoma	NOUN
fnp-3271	214	17	is	be	AUX
fnp-3271	214	18	a	a	DET
fnp-3271	214	19	distinct	distinct	ADJ
fnp-3271	214	20	subtype	subtype	NOUN
fnp-3271	214	21	.	.	PUNCT
fnp-3271	215	1	acta	acta	PROPN
fnp-3271	215	2	neuropathol	neuropathol	PROPN
fnp-3271	215	3	,	,	PUNCT
fnp-3271	215	4	2020	2020	NUM
fnp-3271	215	5	.	.	PUNCT
fnp-3271	216	1	140(4	140(4	NUM
fnp-3271	216	2	):	):	PUNCT
fnp-3271	216	3	p.	p.	NOUN
fnp-3271	216	4	569	569	NUM
fnp-3271	216	5	-	-	SYM
fnp-3271	216	6	581	581	NUM
fnp-3271	216	7	.	.	X
fnp-3271	217	1	2	2	NUM
fnp-3271	217	2	.	.	X
fnp-3271	217	3	ryall	ryall	PROPN
fnp-3271	217	4	,	,	PUNCT
fnp-3271	217	5	s.	s.	PROPN
fnp-3271	217	6	,	,	PUNCT
fnp-3271	217	7	et	et	PROPN
fnp-3271	217	8	al	al	PROPN
fnp-3271	217	9	.	.	PROPN
fnp-3271	217	10	,	,	PUNCT
fnp-3271	217	11	integrated	integrate	VERB
fnp-3271	217	12	molecular	molecular	ADJ
fnp-3271	217	13	and	and	CCONJ
fnp-3271	217	14	clinical	clinical	ADJ
fnp-3271	217	15	analysis	analysis	NOUN
fnp-3271	217	16	of	of	ADP
fnp-3271	217	17	1,000	1,000	NUM
fnp-3271	217	18	pediatric	pediatric	ADJ
fnp-3271	217	19	low	low	ADJ
fnp-3271	217	20	-	-	PUNCT
fnp-3271	217	21	grade	grade	NOUN
fnp-3271	217	22	gliomas	glioma	NOUN
fnp-3271	217	23	.	.	PUNCT
fnp-3271	218	1	cancer	cancer	NOUN
fnp-3271	218	2	cell	cell	NOUN
fnp-3271	218	3	,	,	PUNCT
fnp-3271	218	4	2020	2020	NUM
fnp-3271	218	5	.	.	PUNCT
fnp-3271	219	1	37(4	37(4	X
fnp-3271	219	2	):	):	PUNCT
fnp-3271	219	3	p.	p.	NOUN
fnp-3271	219	4	569	569	NUM
fnp-3271	219	5	-	-	SYM
fnp-3271	219	6	583	583	NUM
fnp-3271	219	7	e5	e5	NOUN
fnp-3271	219	8	.	.	PUNCT
fnp-3271	220	1	3	3	X
fnp-3271	220	2	.	.	X
fnp-3271	220	3	clarke	clarke	PROPN
fnp-3271	220	4	,	,	PUNCT
fnp-3271	220	5	m.	m.	NOUN
fnp-3271	220	6	,	,	PUNCT
fnp-3271	220	7	et	et	PROPN
fnp-3271	220	8	al	al	PROPN
fnp-3271	220	9	.	.	PROPN
fnp-3271	220	10	,	,	PUNCT
fnp-3271	220	11	infant	infant	VERB
fnp-3271	220	12	high	high	ADJ
fnp-3271	220	13	-	-	PUNCT
fnp-3271	220	14	grade	grade	NOUN
fnp-3271	220	15	gliomas	glioma	NOUN
fnp-3271	220	16	comprise	comprise	VERB
fnp-3271	220	17	multiple	multiple	ADJ
fnp-3271	220	18	subgroups	subgroup	NOUN
fnp-3271	220	19	characterized	characterize	VERB
fnp-3271	220	20	by	by	ADP
fnp-3271	220	21	novel	novel	ADJ
fnp-3271	220	22	targetable	targetable	ADJ
fnp-3271	220	23	gene	gene	NOUN
fnp-3271	220	24	fusions	fusion	NOUN
fnp-3271	220	25	and	and	CCONJ
fnp-3271	220	26	favorable	favorable	ADJ
fnp-3271	220	27	outcomes	outcome	NOUN
fnp-3271	220	28	.	.	PUNCT
fnp-3271	221	1	cancer	cancer	NOUN
fnp-3271	221	2	discov	discov	NOUN
fnp-3271	221	3	,	,	PUNCT
fnp-3271	221	4	2020	2020	NUM
fnp-3271	221	5	.	.	PUNCT
fnp-3271	222	1	10(7	10(7	NUM
fnp-3271	222	2	):	):	PUNCT
fnp-3271	222	3	p.	p.	NOUN
fnp-3271	222	4	942	942	NUM
fnp-3271	222	5	-	-	SYM
fnp-3271	222	6	963	963	NUM
fnp-3271	222	7	.	.	NOUN
fnp-3271	223	1	4	4	NUM
fnp-3271	223	2	.	.	X
fnp-3271	223	3	touat	touat	PROPN
fnp-3271	223	4	,	,	PUNCT
fnp-3271	223	5	m.	m.	NOUN
fnp-3271	223	6	,	,	PUNCT
fnp-3271	223	7	et	et	PROPN
fnp-3271	223	8	al	al	PROPN
fnp-3271	223	9	.	.	PROPN
fnp-3271	223	10	,	,	PUNCT
fnp-3271	223	11	mechanisms	mechanism	NOUN
fnp-3271	223	12	and	and	CCONJ
fnp-3271	223	13	therapeutic	therapeutic	ADJ
fnp-3271	223	14	implications	implication	NOUN
fnp-3271	223	15	of	of	ADP
fnp-3271	223	16	hypermutation	hypermutation	NOUN
fnp-3271	223	17	in	in	ADP
fnp-3271	223	18	gliomas	glioma	NOUN
fnp-3271	223	19	.	.	PUNCT
fnp-3271	224	1	nature	nature	NOUN
fnp-3271	224	2	,	,	PUNCT
fnp-3271	224	3	2020	2020	NUM
fnp-3271	224	4	.	.	PUNCT
fnp-3271	225	1	580(7804	580(7804	NOUN
fnp-3271	225	2	):	):	PUNCT
fnp-3271	225	3	p.	p.	NOUN
fnp-3271	225	4	517	517	NUM
fnp-3271	225	5	-	-	SYM
fnp-3271	225	6	523	523	NUM
fnp-3271	225	7	.	.	PUNCT
fnp-3271	226	1	5	5	NUM
fnp-3271	226	2	.	.	X
fnp-3271	226	3	klemm	klemm	NOUN
fnp-3271	226	4	,	,	PUNCT
fnp-3271	226	5	f.	f.	PROPN
fnp-3271	226	6	,	,	PUNCT
fnp-3271	226	7	et	et	PROPN
fnp-3271	226	8	al	al	PROPN
fnp-3271	226	9	.	.	PROPN
fnp-3271	226	10	,	,	PUNCT
fnp-3271	226	11	interrogation	interrogation	NOUN
fnp-3271	226	12	of	of	ADP
fnp-3271	226	13	the	the	DET
fnp-3271	226	14	microenvironmental	microenvironmental	ADJ
fnp-3271	226	15	landscape	landscape	NOUN
fnp-3271	226	16	in	in	ADP
fnp-3271	226	17	brain	brain	NOUN
fnp-3271	226	18	tumors	tumor	NOUN
fnp-3271	226	19	reveals	reveal	VERB
fnp-3271	226	20	disease	disease	NOUN
fnp-3271	226	21	-	-	PUNCT
fnp-3271	226	22	specific	specific	ADJ
fnp-3271	226	23	alterations	alteration	NOUN
fnp-3271	226	24	of	of	ADP
fnp-3271	226	25	immune	immune	ADJ
fnp-3271	226	26	cells	cell	NOUN
fnp-3271	226	27	.	.	PUNCT
fnp-3271	227	1	cell	cell	NOUN
fnp-3271	227	2	,	,	PUNCT
fnp-3271	227	3	2020	2020	NUM
fnp-3271	227	4	.	.	PUNCT
fnp-3271	228	1	181(7	181(7	NUM
fnp-3271	228	2	):	):	PUNCT
fnp-3271	228	3	p.	p.	NOUN
fnp-3271	228	4	1643	1643	NUM
fnp-3271	228	5	-	-	SYM
fnp-3271	228	6	1660	1660	NUM
fnp-3271	228	7	e17	e17	NOUN
fnp-3271	228	8	.	.	PUNCT
fnp-3271	229	1	6	6	X
fnp-3271	229	2	.	.	X
fnp-3271	229	3	friebel	friebel	PROPN
fnp-3271	229	4	,	,	PUNCT
fnp-3271	229	5	e.	e.	PROPN
fnp-3271	229	6	,	,	PUNCT
fnp-3271	229	7	et	et	PROPN
fnp-3271	229	8	al	al	PROPN
fnp-3271	229	9	.	.	PROPN
fnp-3271	229	10	,	,	PUNCT
fnp-3271	229	11	single	single	ADJ
fnp-3271	229	12	-	-	PUNCT
fnp-3271	229	13	cell	cell	NOUN
fnp-3271	229	14	mapping	mapping	NOUN
fnp-3271	229	15	of	of	ADP
fnp-3271	229	16	human	human	ADJ
fnp-3271	229	17	brain	brain	NOUN
fnp-3271	229	18	cancer	cancer	NOUN
fnp-3271	229	19	reveals	reveal	VERB
fnp-3271	229	20	tumor	tumor	NOUN
fnp-3271	229	21	-	-	PUNCT
fnp-3271	229	22	specific	specific	ADJ
fnp-3271	229	23	instruction	instruction	NOUN
fnp-3271	229	24	of	of	ADP
fnp-3271	229	25	tissue	tissue	NOUN
fnp-3271	229	26	-	-	PUNCT
fnp-3271	229	27	invading	invade	VERB
fnp-3271	229	28	leukocytes	leukocyte	NOUN
fnp-3271	229	29	.	.	PUNCT
fnp-3271	230	1	cell	cell	NOUN
fnp-3271	230	2	,	,	PUNCT
fnp-3271	230	3	2020	2020	NUM
fnp-3271	230	4	.	.	PUNCT
fnp-3271	231	1	181(7	181(7	NUM
fnp-3271	231	2	):	):	PUNCT
fnp-3271	231	3	p.	p.	NOUN
fnp-3271	231	4	1626	1626	NUM
fnp-3271	231	5	-	-	SYM
fnp-3271	231	6	1642	1642	NUM
fnp-3271	231	7	e20	e20	NOUN
fnp-3271	231	8	.	.	PUNCT
fnp-3271	232	1	7	7	X
fnp-3271	232	2	.	.	X
fnp-3271	232	3	bayik	bayik	NOUN
fnp-3271	232	4	,	,	PUNCT
fnp-3271	232	5	d.	d.	PROPN
fnp-3271	232	6	,	,	PUNCT
fnp-3271	232	7	et	et	PROPN
fnp-3271	232	8	al	al	PROPN
fnp-3271	232	9	.	.	PROPN
fnp-3271	232	10	,	,	PUNCT
fnp-3271	232	11	myeloid	myeloid	ADJ
fnp-3271	232	12	-	-	PUNCT
fnp-3271	232	13	derived	derive	VERB
fnp-3271	232	14	suppressor	suppressor	NOUN
fnp-3271	232	15	cell	cell	NOUN
fnp-3271	232	16	subsets	subset	NOUN
fnp-3271	232	17	drive	drive	VERB
fnp-3271	232	18	glioblastoma	glioblastoma	NOUN
fnp-3271	232	19	growth	growth	NOUN
fnp-3271	232	20	in	in	ADP
fnp-3271	232	21	a	a	DET
fnp-3271	232	22	sex	sex	NOUN
fnp-3271	232	23	-	-	PUNCT
fnp-3271	232	24	specific	specific	ADJ
fnp-3271	232	25	manner	manner	NOUN
fnp-3271	232	26	.	.	PUNCT
fnp-3271	233	1	cancer	cancer	NOUN
fnp-3271	233	2	discov	discov	NOUN
fnp-3271	233	3	,	,	PUNCT
fnp-3271	233	4	2020	2020	NUM
fnp-3271	233	5	.	.	PUNCT
fnp-3271	234	1	10(8	10(8	NUM
fnp-3271	234	2	):	):	PUNCT
fnp-3271	234	3	p.	p.	NOUN
fnp-3271	234	4	1210	1210	NUM
fnp-3271	234	5	-	-	SYM
fnp-3271	234	6	1225	1225	NUM
fnp-3271	234	7	.	.	PUNCT
fnp-3271	235	1	8	8	X
fnp-3271	235	2	.	.	X
fnp-3271	235	3	song	song	PROPN
fnp-3271	235	4	,	,	PUNCT
fnp-3271	235	5	e.	e.	PROPN
fnp-3271	235	6	,	,	PUNCT
fnp-3271	235	7	et	et	PROPN
fnp-3271	235	8	al	al	PROPN
fnp-3271	235	9	.	.	PROPN
fnp-3271	235	10	,	,	PUNCT
fnp-3271	235	11	vegf	vegf	PROPN
fnp-3271	235	12	-	-	PUNCT
fnp-3271	235	13	c	c	NOUN
fnp-3271	235	14	-	-	PUNCT
fnp-3271	235	15	driven	drive	VERB
fnp-3271	235	16	lymphatic	lymphatic	ADJ
fnp-3271	235	17	drainage	drainage	NOUN
fnp-3271	235	18	enables	enable	VERB
fnp-3271	235	19	immunosurveillance	immunosurveillance	NOUN
fnp-3271	235	20	of	of	ADP
fnp-3271	235	21	brain	brain	NOUN
fnp-3271	235	22	tumours	tumour	NOUN
fnp-3271	235	23	.	.	PUNCT
fnp-3271	236	1	nature	nature	NOUN
fnp-3271	236	2	,	,	PUNCT
fnp-3271	236	3	2020	2020	NUM
fnp-3271	236	4	.	.	PUNCT
fnp-3271	237	1	577(7792	577(7792	NUM
fnp-3271	237	2	):	):	PUNCT
fnp-3271	238	1	p.	p.	NOUN
fnp-3271	238	2	689	689	NUM
fnp-3271	238	3	-	-	SYM
fnp-3271	238	4	694	694	NUM
fnp-3271	238	5	.	.	PUNCT
fnp-3271	238	6	9	9	NUM
fnp-3271	238	7	.	.	X
fnp-3271	238	8	hu	hu	PROPN
fnp-3271	238	9	,	,	PUNCT
fnp-3271	238	10	x.	x.	PROPN
fnp-3271	238	11	,	,	PUNCT
fnp-3271	238	12	et	et	PROPN
fnp-3271	238	13	al	al	PROPN
fnp-3271	238	14	.	.	PROPN
fnp-3271	238	15	,	,	PUNCT
fnp-3271	238	16	meningeal	meningeal	ADJ
fnp-3271	238	17	lymphatic	lymphatic	ADJ
fnp-3271	238	18	vessels	vessel	NOUN
fnp-3271	238	19	regulate	regulate	VERB
fnp-3271	238	20	brain	brain	NOUN
fnp-3271	238	21	tumor	tumor	NOUN
fnp-3271	238	22	drainage	drainage	NOUN
fnp-3271	238	23	and	and	CCONJ
fnp-3271	238	24	immunity	immunity	NOUN
fnp-3271	238	25	.	.	PUNCT
fnp-3271	239	1	cell	cell	NOUN
fnp-3271	239	2	res	re	NOUN
fnp-3271	239	3	,	,	PUNCT
fnp-3271	239	4	2020	2020	NUM
fnp-3271	239	5	.	.	PUNCT
fnp-3271	240	1	30(3	30(3	NUM
fnp-3271	240	2	):	):	PUNCT
fnp-3271	240	3	p.	p.	NOUN
fnp-3271	240	4	229	229	NUM
fnp-3271	240	5	-	-	SYM
fnp-3271	240	6	243	243	NUM
fnp-3271	240	7	.	.	PUNCT
fnp-3271	240	8	10	10	NUM
fnp-3271	240	9	.	.	PUNCT
fnp-3271	241	1	pine	pine	PROPN
fnp-3271	241	2	,	,	PUNCT
fnp-3271	241	3	a.r	a.r	PROPN
fnp-3271	241	4	.	.	PROPN
fnp-3271	241	5	,	,	PUNCT
fnp-3271	241	6	et	et	PROPN
fnp-3271	241	7	al	al	PROPN
fnp-3271	241	8	.	.	PROPN
fnp-3271	241	9	,	,	PUNCT
fnp-3271	241	10	tumor	tumor	NOUN
fnp-3271	241	11	microenvironment	microenvironment	NOUN
fnp-3271	241	12	is	be	AUX
fnp-3271	241	13	critical	critical	ADJ
fnp-3271	241	14	for	for	ADP
fnp-3271	241	15	the	the	DET
fnp-3271	241	16	maintenance	maintenance	NOUN
fnp-3271	241	17	of	of	ADP
fnp-3271	241	18	cellular	cellular	ADJ
fnp-3271	241	19	states	state	NOUN
fnp-3271	241	20	found	find	VERB
fnp-3271	241	21	in	in	ADP
fnp-3271	241	22	primary	primary	ADJ
fnp-3271	241	23	glioblastomas	glioblastoma	NOUN
fnp-3271	241	24	.	.	PUNCT
fnp-3271	242	1	cancer	cancer	NOUN
fnp-3271	242	2	discov	discov	NOUN
fnp-3271	242	3	,	,	PUNCT
fnp-3271	242	4	2020	2020	NUM
fnp-3271	242	5	.	.	PUNCT
fnp-3271	243	1	10(7	10(7	NUM
fnp-3271	243	2	):	):	PUNCT
fnp-3271	243	3	p.	p.	NOUN
fnp-3271	243	4	964	964	NUM
fnp-3271	243	5	-	-	SYM
fnp-3271	243	6	979	979	NUM
fnp-3271	243	7	.	.	PUNCT
fnp-3271	243	8	11	11	NUM
fnp-3271	243	9	.	.	PUNCT
fnp-3271	244	1	waszak	waszak	NOUN
fnp-3271	244	2	,	,	PUNCT
fnp-3271	244	3	s.m	s.m	PROPN
fnp-3271	244	4	.	.	PROPN
fnp-3271	244	5	,	,	PUNCT
fnp-3271	244	6	et	et	PROPN
fnp-3271	244	7	al	al	PROPN
fnp-3271	244	8	.	.	PROPN
fnp-3271	244	9	,	,	PUNCT
fnp-3271	244	10	germline	germline	NOUN
fnp-3271	244	11	elongator	elongator	NOUN
fnp-3271	244	12	mutations	mutation	NOUN
fnp-3271	244	13	in	in	ADP
fnp-3271	244	14	sonic	sonic	ADJ
fnp-3271	244	15	hedgehog	hedgehog	ADJ
fnp-3271	244	16	medulloblastoma	medulloblastoma	NOUN
fnp-3271	244	17	.	.	PUNCT
fnp-3271	245	1	nature	nature	NOUN
fnp-3271	245	2	,	,	PUNCT
fnp-3271	245	3	2020	2020	NUM
fnp-3271	245	4	.	.	PUNCT
fnp-3271	246	1	580(7803	580(7803	NUM
fnp-3271	246	2	):	):	PUNCT
fnp-3271	246	3	p.	p.	NOUN
fnp-3271	246	4	396	396	NUM
fnp-3271	246	5	-	-	SYM
fnp-3271	246	6	401	401	NUM
fnp-3271	246	7	.	.	PUNCT
fnp-3271	247	1	12	12	NUM
fnp-3271	247	2	.	.	PUNCT
fnp-3271	247	3	begemann	begemann	PROPN
fnp-3271	247	4	,	,	PUNCT
fnp-3271	247	5	m.	m.	NOUN
fnp-3271	247	6	,	,	PUNCT
fnp-3271	247	7	et	et	PROPN
fnp-3271	247	8	al	al	PROPN
fnp-3271	247	9	.	.	PROPN
fnp-3271	247	10	,	,	PUNCT
fnp-3271	247	11	germline	germline	VERB
fnp-3271	247	12	gpr161	gpr161	NOUN
fnp-3271	247	13	mutations	mutation	NOUN
fnp-3271	247	14	predispose	predispose	VERB
fnp-3271	247	15	to	to	ADP
fnp-3271	247	16	pediatric	pediatric	ADJ
fnp-3271	247	17	medulloblastoma	medulloblastoma	NOUN
fnp-3271	247	18	.	.	PUNCT
fnp-3271	248	1	j	j	PROPN
fnp-3271	248	2	clin	clin	PROPN
fnp-3271	248	3	oncol	oncol	PROPN
fnp-3271	248	4	,	,	PUNCT
fnp-3271	248	5	2020	2020	NUM
fnp-3271	248	6	.	.	PUNCT
fnp-3271	249	1	38(1	38(1	NOUN
fnp-3271	249	2	):	):	PUNCT
fnp-3271	249	3	p.	p.	NOUN
fnp-3271	249	4	43	43	NUM
fnp-3271	249	5	-	-	SYM
fnp-3271	249	6	50	50	NUM
fnp-3271	249	7	.	.	NOUN
fnp-3271	250	1	13	13	NUM
fnp-3271	250	2	.	.	PUNCT
fnp-3271	250	3	nassiri	nassiri	PROPN
fnp-3271	250	4	,	,	PUNCT
fnp-3271	250	5	f.	f.	PROPN
fnp-3271	250	6	,	,	PUNCT
fnp-3271	250	7	et	et	PROPN
fnp-3271	250	8	al	al	PROPN
fnp-3271	250	9	.	.	PROPN
fnp-3271	250	10	,	,	PUNCT
fnp-3271	250	11	detection	detection	NOUN
fnp-3271	250	12	and	and	CCONJ
fnp-3271	250	13	discrimination	discrimination	NOUN
fnp-3271	250	14	of	of	ADP
fnp-3271	250	15	intracranial	intracranial	ADJ
fnp-3271	250	16	tumors	tumor	NOUN
fnp-3271	250	17	using	use	VERB
fnp-3271	250	18	plasma	plasma	NOUN
fnp-3271	250	19	cell	cell	NOUN
fnp-3271	250	20	-	-	PUNCT
fnp-3271	250	21	free	free	ADJ
fnp-3271	250	22	dna	dna	PROPN
fnp-3271	250	23	methylomes	methylome	NOUN
fnp-3271	250	24	.	.	PUNCT
fnp-3271	251	1	nat	nat	PROPN
fnp-3271	251	2	med	med	PROPN
fnp-3271	251	3	,	,	PUNCT
fnp-3271	251	4	2020	2020	NUM
fnp-3271	251	5	.	.	PUNCT
fnp-3271	252	1	26(7	26(7	NUM
fnp-3271	252	2	):	):	PUNCT
fnp-3271	253	1	p.	p.	NOUN
fnp-3271	253	2	1044	1044	NUM
fnp-3271	253	3	-	-	SYM
fnp-3271	253	4	1047	1047	NUM
fnp-3271	253	5	.	.	PUNCT
fnp-3271	254	1	14	14	NUM
fnp-3271	254	2	.	.	PUNCT
fnp-3271	254	3	nejman	nejman	PROPN
fnp-3271	254	4	,	,	PUNCT
fnp-3271	254	5	d.	d.	PROPN
fnp-3271	254	6	,	,	PUNCT
fnp-3271	254	7	et	et	PROPN
fnp-3271	254	8	al	al	PROPN
fnp-3271	254	9	.	.	PROPN
fnp-3271	254	10	,	,	PUNCT
fnp-3271	254	11	the	the	DET
fnp-3271	254	12	human	human	ADJ
fnp-3271	254	13	tumor	tumor	NOUN
fnp-3271	254	14	microbiome	microbiome	NOUN
fnp-3271	254	15	is	be	AUX
fnp-3271	254	16	composed	compose	VERB
fnp-3271	254	17	of	of	ADP
fnp-3271	254	18	tumor	tumor	NOUN
fnp-3271	254	19	type	type	NOUN
fnp-3271	254	20	-	-	PUNCT
fnp-3271	254	21	specific	specific	ADJ
fnp-3271	254	22	intracellular	intracellular	ADJ
fnp-3271	254	23	bacteria	bacteria	NOUN
fnp-3271	254	24	.	.	PUNCT
fnp-3271	255	1	science	science	NOUN
fnp-3271	255	2	,	,	PUNCT
fnp-3271	255	3	2020	2020	NUM
fnp-3271	255	4	.	.	PUNCT
fnp-3271	256	1	368(6494	368(6494	NUM
fnp-3271	256	2	):	):	PUNCT
fnp-3271	257	1	p.	p.	NOUN
fnp-3271	257	2	973	973	NUM
fnp-3271	257	3	-	-	SYM
fnp-3271	257	4	980	980	NUM
fnp-3271	257	5	.	.	NOUN
fnp-3271	257	6	15	15	NUM
fnp-3271	257	7	.	.	PUNCT
fnp-3271	257	8	wesseling	wesseling	NOUN
fnp-3271	257	9	,	,	PUNCT
fnp-3271	257	10	p.	p.	NOUN
fnp-3271	257	11	and	and	CCONJ
fnp-3271	257	12	d.	d.	PROPN
fnp-3271	257	13	capper	capper	PROPN
fnp-3271	257	14	,	,	PUNCT
fnp-3271	257	15	who	who	PRON
fnp-3271	257	16	2016	2016	NUM
fnp-3271	257	17	classification	classification	NOUN
fnp-3271	257	18	of	of	ADP
fnp-3271	257	19	gliomas	glioma	NOUN
fnp-3271	257	20	.	.	PUNCT
fnp-3271	258	1	neuropathol	neuropathol	NOUN
fnp-3271	258	2	appl	appl	PROPN
fnp-3271	258	3	neurobiol	neurobiol	PROPN
fnp-3271	258	4	,	,	PUNCT
fnp-3271	258	5	2018	2018	NUM
fnp-3271	258	6	.	.	PUNCT
fnp-3271	259	1	44(2	44(2	NOUN
fnp-3271	259	2	):	):	PUNCT
fnp-3271	260	1	p.	p.	NOUN
fnp-3271	260	2	139	139	NUM
fnp-3271	260	3	-	-	SYM
fnp-3271	260	4	150	150	NUM
fnp-3271	260	5	.	.	PUNCT
fnp-3271	260	6	16	16	NUM
fnp-3271	260	7	.	.	PUNCT
fnp-3271	261	1	brat	brat	NOUN
fnp-3271	261	2	,	,	PUNCT
fnp-3271	261	3	d.j	d.j	PROPN
fnp-3271	261	4	.	.	PROPN
fnp-3271	261	5	,	,	PUNCT
fnp-3271	261	6	et	et	PROPN
fnp-3271	261	7	al	al	PROPN
fnp-3271	261	8	.	.	PROPN
fnp-3271	261	9	,	,	PUNCT
fnp-3271	261	10	cimpact	cimpact	ADJ
fnp-3271	261	11	-	-	PUNCT
fnp-3271	261	12	now	now	ADV
fnp-3271	261	13	update	update	NOUN
fnp-3271	261	14	5	5	NUM
fnp-3271	261	15	:	:	PUNCT
fnp-3271	261	16	recommended	recommend	VERB
fnp-3271	261	17	grading	grading	NOUN
fnp-3271	261	18	criteria	criterion	NOUN
fnp-3271	261	19	and	and	CCONJ
fnp-3271	261	20	terminologies	terminology	NOUN
fnp-3271	261	21	for	for	ADP
fnp-3271	261	22	idh	idh	NOUN
fnp-3271	261	23	-	-	PUNCT
fnp-3271	261	24	mutant	mutant	NOUN
fnp-3271	261	25	astrocytomas	astrocytoma	NOUN
fnp-3271	261	26	.	.	PUNCT
fnp-3271	262	1	acta	acta	PROPN
fnp-3271	262	2	neuropathol	neuropathol	PROPN
fnp-3271	262	3	,	,	PUNCT
fnp-3271	262	4	2020	2020	NUM
fnp-3271	262	5	.	.	PUNCT
fnp-3271	263	1	139(3	139(3	NUM
fnp-3271	263	2	):	):	PUNCT
fnp-3271	263	3	p.	p.	NOUN
fnp-3271	263	4	603	603	NUM
fnp-3271	263	5	-	-	SYM
fnp-3271	263	6	608	608	NUM
fnp-3271	263	7	.	.	PUNCT
fnp-3271	264	1	17	17	NUM
fnp-3271	264	2	.	.	X
fnp-3271	265	1	louis	louis	PROPN
fnp-3271	265	2	,	,	PUNCT
fnp-3271	265	3	d.n	d.n	PROPN
fnp-3271	265	4	.	.	PROPN
fnp-3271	265	5	,	,	PUNCT
fnp-3271	265	6	et	et	PROPN
fnp-3271	265	7	al	al	PROPN
fnp-3271	265	8	.	.	PROPN
fnp-3271	265	9	,	,	PUNCT
fnp-3271	265	10	cimpact	cimpact	ADJ
fnp-3271	265	11	-	-	PUNCT
fnp-3271	265	12	now	now	ADV
fnp-3271	265	13	update	update	NOUN
fnp-3271	265	14	6	6	NUM
fnp-3271	265	15	:	:	PUNCT
fnp-3271	265	16	new	new	ADJ
fnp-3271	265	17	entity	entity	NOUN
fnp-3271	265	18	and	and	CCONJ
fnp-3271	265	19	diagnostic	diagnostic	ADJ
fnp-3271	265	20	principle	principle	ADJ
fnp-3271	265	21	recommendations	recommendation	NOUN
fnp-3271	265	22	of	of	ADP
fnp-3271	265	23	the	the	DET
fnp-3271	265	24	cimpact	cimpact	ADJ
fnp-3271	265	25	-	-	PUNCT
fnp-3271	265	26	utrecht	utrecht	NOUN
fnp-3271	265	27	meeting	meeting	NOUN
fnp-3271	265	28	on	on	ADP
fnp-3271	265	29	future	future	ADJ
fnp-3271	265	30	cns	cns	NOUN
fnp-3271	265	31	tumor	tumor	NOUN
fnp-3271	265	32	classification	classification	NOUN
fnp-3271	265	33	and	and	CCONJ
fnp-3271	265	34	grading	grade	VERB
fnp-3271	265	35	.	.	PUNCT
fnp-3271	266	1	brain	brain	NOUN
fnp-3271	266	2	pathol	pathol	NOUN
fnp-3271	266	3	,	,	PUNCT
fnp-3271	266	4	2020	2020	NUM
fnp-3271	266	5	.	.	PUNCT
fnp-3271	267	1	30(4	30(4	NUM
fnp-3271	267	2	):	):	PUNCT
fnp-3271	267	3	p.	p.	NOUN
fnp-3271	267	4	844	844	NUM
fnp-3271	267	5	-	-	SYM
fnp-3271	267	6	856	856	NUM
fnp-3271	267	7	.	.	PUNCT
fnp-3271	268	1	18	18	NUM
fnp-3271	268	2	.	.	PUNCT
fnp-3271	269	1	guerreiro	guerreiro	PROPN
fnp-3271	269	2	stucklin	stucklin	PROPN
fnp-3271	269	3	,	,	PUNCT
fnp-3271	269	4	a.s	a.s	PROPN
fnp-3271	269	5	.	.	PROPN
fnp-3271	269	6	,	,	PUNCT
fnp-3271	269	7	et	et	PROPN
fnp-3271	269	8	al	al	PROPN
fnp-3271	269	9	.	.	PROPN
fnp-3271	269	10	,	,	PUNCT
fnp-3271	269	11	alterations	alteration	NOUN
fnp-3271	269	12	in	in	ADP
fnp-3271	269	13	alk	alk	PROPN
fnp-3271	269	14	/	/	SYM
fnp-3271	269	15	ros1	ros1	PROPN
fnp-3271	269	16	/	/	SYM
fnp-3271	269	17	ntrk	ntrk	PROPN
fnp-3271	269	18	/	/	SYM
fnp-3271	269	19	met	meet	VERB
fnp-3271	269	20	drive	drive	VERB
fnp-3271	269	21	a	a	DET
fnp-3271	269	22	group	group	NOUN
fnp-3271	269	23	of	of	ADP
fnp-3271	269	24	infantile	infantile	ADJ
fnp-3271	269	25	hemispheric	hemispheric	ADJ
fnp-3271	269	26	gliomas	glioma	NOUN
fnp-3271	269	27	.	.	PUNCT
fnp-3271	270	1	nat	nat	PROPN
fnp-3271	270	2	commun	commun	PROPN
fnp-3271	270	3	,	,	PUNCT
fnp-3271	270	4	2019	2019	NUM
fnp-3271	270	5	.	.	PUNCT
fnp-3271	271	1	10(1	10(1	NUM
fnp-3271	271	2	):	):	PUNCT
fnp-3271	271	3	p.	p.	NOUN
fnp-3271	271	4	4343	4343	NUM
fnp-3271	271	5	.	.	PUNCT
fnp-3271	272	1	19	19	NUM
fnp-3271	272	2	.	.	X
fnp-3271	272	3	wong	wong	PROPN
fnp-3271	272	4	,	,	PUNCT
fnp-3271	272	5	m.	m.	NOUN
fnp-3271	272	6	,	,	PUNCT
fnp-3271	272	7	et	et	PROPN
fnp-3271	272	8	al	al	PROPN
fnp-3271	272	9	.	.	PROPN
fnp-3271	272	10	,	,	PUNCT
fnp-3271	272	11	whole	whole	ADJ
fnp-3271	272	12	genome	genome	NOUN
fnp-3271	272	13	,	,	PUNCT
fnp-3271	272	14	transcriptome	transcriptome	NOUN
fnp-3271	272	15	and	and	CCONJ
fnp-3271	272	16	methylome	methylome	ADJ
fnp-3271	272	17	profiling	profiling	NOUN
fnp-3271	272	18	enhances	enhance	VERB
fnp-3271	272	19	actionable	actionable	ADJ
fnp-3271	272	20	target	target	NOUN
fnp-3271	272	21	discovery	discovery	NOUN
fnp-3271	272	22	in	in	ADP
fnp-3271	272	23	high	high	ADJ
fnp-3271	272	24	-	-	PUNCT
fnp-3271	272	25	risk	risk	NOUN
fnp-3271	272	26	pediatric	pediatric	ADJ
fnp-3271	272	27	cancer	cancer	NOUN
fnp-3271	272	28	.	.	PUNCT
fnp-3271	273	1	nat	nat	PROPN
fnp-3271	273	2	med	med	PROPN
fnp-3271	273	3	,	,	PUNCT
fnp-3271	273	4	2020	2020	NUM
fnp-3271	273	5	.	.	PUNCT
fnp-3271	274	1	26(11	26(11	NUM
fnp-3271	274	2	):	):	PUNCT
fnp-3271	274	3	p.	p.	NOUN
fnp-3271	274	4	1742	1742	NUM
fnp-3271	274	5	-	-	SYM
fnp-3271	274	6	1753	1753	NUM
fnp-3271	274	7	.	.	PUNCT
fnp-3271	275	1	20	20	NUM
fnp-3271	275	2	.	.	X
fnp-3271	275	3	barthel	barthel	PROPN
fnp-3271	275	4	,	,	PUNCT
fnp-3271	275	5	f.p	f.p	PROPN
fnp-3271	275	6	.	.	PROPN
fnp-3271	275	7	,	,	PUNCT
fnp-3271	275	8	et	et	PROPN
fnp-3271	275	9	al	al	PROPN
fnp-3271	275	10	.	.	PROPN
fnp-3271	275	11	,	,	PUNCT
fnp-3271	275	12	longitudinal	longitudinal	ADJ
fnp-3271	275	13	molecular	molecular	ADJ
fnp-3271	275	14	trajectories	trajectory	NOUN
fnp-3271	275	15	of	of	ADP
fnp-3271	275	16	diffuse	diffuse	ADJ
fnp-3271	275	17	glioma	glioma	NOUN
fnp-3271	275	18	in	in	ADP
fnp-3271	275	19	adults	adult	NOUN
fnp-3271	275	20	.	.	PUNCT
fnp-3271	276	1	nature	nature	NOUN
fnp-3271	276	2	,	,	PUNCT
fnp-3271	276	3	2019	2019	NUM
fnp-3271	276	4	.	.	PUNCT
fnp-3271	277	1	576(7785	576(7785	NUM
fnp-3271	277	2	):	):	PUNCT
fnp-3271	277	3	p.	p.	NOUN
fnp-3271	277	4	112	112	NUM
fnp-3271	277	5	-	-	SYM
fnp-3271	277	6	120	120	NUM
fnp-3271	277	7	.	.	PUNCT
fnp-3271	278	1	21	21	NUM
fnp-3271	278	2	.	.	PUNCT
fnp-3271	279	1	ostrom	ostrom	NOUN
fnp-3271	279	2	,	,	PUNCT
fnp-3271	279	3	q.t	q.t	PROPN
fnp-3271	279	4	.	.	PROPN
fnp-3271	279	5	,	,	PUNCT
fnp-3271	279	6	et	et	PROPN
fnp-3271	279	7	al	al	PROPN
fnp-3271	279	8	.	.	PROPN
fnp-3271	279	9	,	,	PUNCT
fnp-3271	279	10	cbtrus	cbtrus	NOUN
fnp-3271	279	11	statistical	statistical	ADJ
fnp-3271	279	12	report	report	NOUN
fnp-3271	279	13	:	:	PUNCT
fnp-3271	279	14	primary	primary	ADJ
fnp-3271	279	15	brain	brain	NOUN
fnp-3271	279	16	and	and	CCONJ
fnp-3271	279	17	other	other	ADJ
fnp-3271	279	18	central	central	ADJ
fnp-3271	279	19	nervous	nervous	ADJ
fnp-3271	279	20	system	system	NOUN
fnp-3271	279	21	tumors	tumor	NOUN
fnp-3271	279	22	diagnosed	diagnose	VERB
fnp-3271	279	23	in	in	ADP
fnp-3271	279	24	the	the	DET
fnp-3271	279	25	united	united	PROPN
fnp-3271	279	26	states	states	PROPN
fnp-3271	279	27	in	in	ADP
fnp-3271	279	28	2013	2013	NUM
fnp-3271	279	29	-	-	SYM
fnp-3271	279	30	2017	2017	NUM
fnp-3271	279	31	.	.	PUNCT
fnp-3271	280	1	neuro	neuro	PROPN
fnp-3271	280	2	oncol	oncol	PROPN
fnp-3271	280	3	,	,	PUNCT
fnp-3271	280	4	2020	2020	NUM
fnp-3271	280	5	.	.	PUNCT
fnp-3271	281	1	22(12	22(12	NUM
fnp-3271	281	2	suppl	suppl	ADV
fnp-3271	281	3	2	2	NUM
fnp-3271	281	4	):	):	PUNCT
fnp-3271	281	5	p.	p.	PROPN
fnp-3271	281	6	iv1	iv1	PROPN
fnp-3271	281	7	-	-	PROPN
fnp-3271	281	8	iv96	iv96	PROPN
fnp-3271	281	9	.	.	PUNCT
fnp-3271	282	1	22	22	NUM
fnp-3271	282	2	.	.	PUNCT
fnp-3271	283	1	ostrom	ostrom	NOUN
fnp-3271	283	2	,	,	PUNCT
fnp-3271	283	3	q.t	q.t	PROPN
fnp-3271	283	4	.	.	PROPN
fnp-3271	283	5	,	,	PUNCT
fnp-3271	283	6	et	et	PROPN
fnp-3271	283	7	al	al	PROPN
fnp-3271	283	8	.	.	PROPN
fnp-3271	283	9	,	,	PUNCT
fnp-3271	283	10	females	female	NOUN
fnp-3271	283	11	have	have	VERB
fnp-3271	283	12	the	the	DET
fnp-3271	283	13	survival	survival	NOUN
fnp-3271	283	14	advantage	advantage	NOUN
fnp-3271	283	15	in	in	ADP
fnp-3271	283	16	glioblastoma	glioblastoma	NOUN
fnp-3271	283	17	.	.	PUNCT
fnp-3271	284	1	neuro	neuro	PROPN
fnp-3271	284	2	oncol	oncol	PROPN
fnp-3271	284	3	,	,	PUNCT
fnp-3271	284	4	2018	2018	NUM
fnp-3271	284	5	.	.	PUNCT
fnp-3271	285	1	20(4	20(4	NOUN
fnp-3271	285	2	):	):	PUNCT
fnp-3271	285	3	p.	p.	NOUN
fnp-3271	285	4	576	576	NUM
fnp-3271	285	5	-	-	SYM
fnp-3271	285	6	577	577	NUM
fnp-3271	285	7	.	.	PUNCT
fnp-3271	286	1	23	23	NUM
fnp-3271	286	2	.	.	X
fnp-3271	287	1	oliver	oliver	PROPN
fnp-3271	287	2	,	,	PUNCT
fnp-3271	287	3	g.	g.	PROPN
fnp-3271	287	4	,	,	PUNCT
fnp-3271	287	5	et	et	PROPN
fnp-3271	287	6	al	al	PROPN
fnp-3271	287	7	.	.	PROPN
fnp-3271	287	8	,	,	PUNCT
fnp-3271	287	9	the	the	DET
fnp-3271	287	10	lymphatic	lymphatic	ADJ
fnp-3271	287	11	vasculature	vasculature	NOUN
fnp-3271	287	12	in	in	ADP
fnp-3271	287	13	the	the	DET
fnp-3271	287	14	21(st	21(st	NUM
fnp-3271	287	15	)	)	PUNCT
fnp-3271	287	16	century	century	NOUN
fnp-3271	287	17	:	:	PUNCT
fnp-3271	287	18	novel	novel	ADJ
fnp-3271	287	19	functional	functional	ADJ
fnp-3271	287	20	roles	role	NOUN
fnp-3271	287	21	in	in	ADP
fnp-3271	287	22	homeostasis	homeostasis	NOUN
fnp-3271	287	23	and	and	CCONJ
fnp-3271	287	24	disease	disease	NOUN
fnp-3271	287	25	.	.	PUNCT
fnp-3271	288	1	cell	cell	NOUN
fnp-3271	288	2	,	,	PUNCT
fnp-3271	288	3	2020	2020	NUM
fnp-3271	288	4	.	.	PUNCT
fnp-3271	289	1	182(2	182(2	NUM
fnp-3271	289	2	):	):	PUNCT
fnp-3271	290	1	p.	p.	NOUN
fnp-3271	290	2	270	270	NUM
fnp-3271	290	3	-	-	SYM
fnp-3271	290	4	296	296	NUM
fnp-3271	290	5	.	.	PUNCT
fnp-3271	290	6	24	24	NUM
fnp-3271	290	7	.	.	PUNCT
fnp-3271	291	1	waszak	waszak	NOUN
fnp-3271	291	2	,	,	PUNCT
fnp-3271	291	3	s.m	s.m	PROPN
fnp-3271	291	4	.	.	PROPN
fnp-3271	291	5	,	,	PUNCT
fnp-3271	291	6	et	et	PROPN
fnp-3271	291	7	al	al	PROPN
fnp-3271	291	8	.	.	PROPN
fnp-3271	291	9	,	,	PUNCT
fnp-3271	291	10	spectrum	spectrum	NOUN
fnp-3271	291	11	and	and	CCONJ
fnp-3271	291	12	prevalence	prevalence	NOUN
fnp-3271	291	13	of	of	ADP
fnp-3271	291	14	genetic	genetic	ADJ
fnp-3271	291	15	predisposition	predisposition	NOUN
fnp-3271	291	16	in	in	ADP
fnp-3271	291	17	medulloblastoma	medulloblastoma	NOUN
fnp-3271	291	18	:	:	PUNCT
fnp-3271	291	19	a	a	DET
fnp-3271	291	20	retrospective	retrospective	ADJ
fnp-3271	291	21	genetic	genetic	ADJ
fnp-3271	291	22	study	study	NOUN
fnp-3271	291	23	and	and	CCONJ
fnp-3271	291	24	prospective	prospective	ADJ
fnp-3271	291	25	validation	validation	NOUN
fnp-3271	291	26	in	in	ADP
fnp-3271	291	27	a	a	DET
fnp-3271	291	28	clinical	clinical	ADJ
fnp-3271	291	29	trial	trial	NOUN
fnp-3271	291	30	cohort	cohort	NOUN
fnp-3271	291	31	.	.	PUNCT
fnp-3271	292	1	lancet	lancet	PROPN
fnp-3271	292	2	oncol	oncol	PROPN
fnp-3271	292	3	,	,	PUNCT
fnp-3271	292	4	2018	2018	NUM
fnp-3271	292	5	.	.	PUNCT
fnp-3271	293	1	19(6	19(6	NUM
fnp-3271	293	2	):	):	PUNCT
fnp-3271	293	3	p.	p.	NOUN
fnp-3271	293	4	785	785	NUM
fnp-3271	293	5	-	-	SYM
fnp-3271	293	6	798	798	NUM
fnp-3271	293	7	.	.	PUNCT
fnp-3271	294	1	25	25	NUM
fnp-3271	294	2	.	.	PUNCT
fnp-3271	295	1	van	van	PROPN
fnp-3271	295	2	der	der	PROPN
fnp-3271	295	3	pol	pol	PROPN
fnp-3271	295	4	,	,	PUNCT
fnp-3271	295	5	y.	y.	PROPN
fnp-3271	295	6	and	and	CCONJ
fnp-3271	295	7	f.	f.	PROPN
fnp-3271	295	8	mouliere	mouliere	PROPN
fnp-3271	295	9	,	,	PUNCT
fnp-3271	295	10	toward	toward	ADP
fnp-3271	295	11	the	the	DET
fnp-3271	295	12	early	early	ADJ
fnp-3271	295	13	detection	detection	NOUN
fnp-3271	295	14	of	of	ADP
fnp-3271	295	15	cancer	cancer	NOUN
fnp-3271	295	16	by	by	ADP
fnp-3271	295	17	decoding	decode	VERB
fnp-3271	295	18	the	the	DET
fnp-3271	295	19	epigenetic	epigenetic	ADJ
fnp-3271	295	20	and	and	CCONJ
fnp-3271	295	21	environmental	environmental	ADJ
fnp-3271	295	22	fingerprints	fingerprint	NOUN
fnp-3271	295	23	of	of	ADP
fnp-3271	295	24	cell	cell	NOUN
fnp-3271	295	25	-	-	PUNCT
fnp-3271	295	26	free	free	ADJ
fnp-3271	295	27	dna	dna	NOUN
fnp-3271	295	28	.	.	PUNCT
fnp-3271	296	1	cancer	cancer	NOUN
fnp-3271	296	2	cell	cell	NOUN
fnp-3271	296	3	,	,	PUNCT
fnp-3271	296	4	2019	2019	NUM
fnp-3271	296	5	.	.	PUNCT
fnp-3271	297	1	36(4	36(4	NUM
fnp-3271	297	2	):	):	PUNCT
fnp-3271	298	1	p.	p.	NOUN
fnp-3271	298	2	350	350	NUM
fnp-3271	298	3	-	-	SYM
fnp-3271	298	4	368	368	NUM
fnp-3271	298	5	.	.	PUNCT
fnp-3271	299	1	26	26	NUM
fnp-3271	299	2	.	.	PUNCT
fnp-3271	299	3	shen	shen	PROPN
fnp-3271	299	4	,	,	PUNCT
fnp-3271	299	5	s.y	s.y	PROPN
fnp-3271	299	6	.	.	PROPN
fnp-3271	299	7	,	,	PUNCT
fnp-3271	299	8	et	et	PROPN
fnp-3271	299	9	al	al	PROPN
fnp-3271	299	10	.	.	PROPN
fnp-3271	299	11	,	,	PUNCT
fnp-3271	299	12	sensitive	sensitive	ADJ
fnp-3271	299	13	tumour	tumour	NOUN
fnp-3271	299	14	detection	detection	NOUN
fnp-3271	299	15	and	and	CCONJ
fnp-3271	299	16	classification	classification	NOUN
fnp-3271	299	17	using	use	VERB
fnp-3271	299	18	plasma	plasma	NOUN
fnp-3271	299	19	cell	cell	NOUN
fnp-3271	299	20	-	-	PUNCT
fnp-3271	299	21	free	free	ADJ
fnp-3271	299	22	dna	dna	PROPN
fnp-3271	299	23	methylomes	methylome	NOUN
fnp-3271	299	24	.	.	PUNCT
fnp-3271	300	1	nature	nature	NOUN
fnp-3271	300	2	,	,	PUNCT
fnp-3271	300	3	2018	2018	NUM
fnp-3271	300	4	.	.	PUNCT
fnp-3271	301	1	563(7732	563(7732	NUM
fnp-3271	301	2	):	):	PUNCT
fnp-3271	301	3	p.	p.	NOUN
fnp-3271	301	4	579	579	NUM
fnp-3271	301	5	-	-	SYM
fnp-3271	301	6	583	583	NUM
fnp-3271	301	7	.	.	PUNCT
fnp-3271	302	1	27	27	NUM
fnp-3271	302	2	.	.	PUNCT
fnp-3271	303	1	nuzzo	nuzzo	PROPN
fnp-3271	303	2	,	,	PUNCT
fnp-3271	303	3	p.v	p.v	PROPN
fnp-3271	303	4	.	.	PROPN
fnp-3271	303	5	,	,	PUNCT
fnp-3271	303	6	et	et	PROPN
fnp-3271	303	7	al	al	PROPN
fnp-3271	303	8	.	.	PROPN
fnp-3271	303	9	,	,	PUNCT
fnp-3271	303	10	detection	detection	NOUN
fnp-3271	303	11	of	of	ADP
fnp-3271	303	12	renal	renal	ADJ
fnp-3271	303	13	cell	cell	NOUN
fnp-3271	303	14	carcinoma	carcinoma	NOUN
fnp-3271	303	15	using	use	VERB
fnp-3271	303	16	plasma	plasma	NOUN
fnp-3271	303	17	and	and	CCONJ
fnp-3271	303	18	urine	urine	NOUN
fnp-3271	303	19	cell	cell	NOUN
fnp-3271	303	20	-	-	PUNCT
fnp-3271	303	21	free	free	ADJ
fnp-3271	303	22	dna	dna	PROPN
fnp-3271	303	23	methylomes	methylome	NOUN
fnp-3271	303	24	.	.	PUNCT
fnp-3271	304	1	nat	nat	PROPN
fnp-3271	304	2	med	med	PROPN
fnp-3271	304	3	,	,	PUNCT
fnp-3271	304	4	2020	2020	NUM
fnp-3271	304	5	.	.	PUNCT
fnp-3271	305	1	26(7	26(7	NUM
fnp-3271	305	2	):	):	PUNCT
fnp-3271	306	1	p.	p.	NOUN
fnp-3271	306	2	1041	1041	NUM
fnp-3271	306	3	-	-	SYM
fnp-3271	306	4	1043	1043	NUM
fnp-3271	306	5	.	.	PUNCT
fnp-3271	307	1	28	28	NUM
fnp-3271	307	2	.	.	PUNCT
fnp-3271	308	1	junttila	junttila	PROPN
fnp-3271	308	2	,	,	PUNCT
fnp-3271	308	3	m.r	m.r	PROPN
fnp-3271	308	4	.	.	PROPN
fnp-3271	308	5	and	and	CCONJ
fnp-3271	308	6	f.j	f.j	PROPN
fnp-3271	308	7	.	.	PROPN
fnp-3271	308	8	de	de	X
fnp-3271	308	9	sauvage	sauvage	PROPN
fnp-3271	308	10	,	,	PUNCT
fnp-3271	308	11	influence	influence	NOUN
fnp-3271	308	12	of	of	ADP
fnp-3271	308	13	tumour	tumour	PROPN
fnp-3271	308	14	micro	micro	NOUN
fnp-3271	308	15	-	-	NOUN
fnp-3271	308	16	environment	environment	ADJ
fnp-3271	308	17	heterogeneity	heterogeneity	NOUN
fnp-3271	308	18	on	on	ADP
fnp-3271	308	19	therapeutic	therapeutic	ADJ
fnp-3271	308	20	response	response	NOUN
fnp-3271	308	21	.	.	PUNCT
fnp-3271	309	1	nature	nature	NOUN
fnp-3271	309	2	,	,	PUNCT
fnp-3271	309	3	2013	2013	NUM
fnp-3271	309	4	.	.	PUNCT
fnp-3271	310	1	501(7467	501(7467	NUM
fnp-3271	310	2	):	):	PUNCT
fnp-3271	310	3	p.	p.	NOUN
fnp-3271	310	4	346	346	NUM
fnp-3271	310	5	-	-	SYM
fnp-3271	310	6	54	54	NUM
fnp-3271	310	7	.	.	PUNCT
fnp-3271	310	8	29	29	NUM
fnp-3271	310	9	.	.	X
fnp-3271	311	1	atreya	atreya	PROPN
fnp-3271	311	2	,	,	PUNCT
fnp-3271	311	3	c.e	c.e	PROPN
fnp-3271	311	4	.	.	PROPN
fnp-3271	311	5	and	and	CCONJ
fnp-3271	311	6	p.j	p.j	PROPN
fnp-3271	311	7	.	.	PROPN
fnp-3271	311	8	turnbaugh	turnbaugh	PROPN
fnp-3271	311	9	,	,	PUNCT
fnp-3271	311	10	probing	probe	VERB
fnp-3271	311	11	the	the	DET
fnp-3271	311	12	tumor	tumor	NOUN
fnp-3271	311	13	micro(b)environment	micro(b)environment	NOUN
fnp-3271	311	14	.	.	PUNCT
fnp-3271	311	15	science	science	NOUN
fnp-3271	311	16	,	,	PUNCT
fnp-3271	311	17	2020	2020	NUM
fnp-3271	311	18	.	.	PUNCT
fnp-3271	312	1	368(6494	368(6494	NUM
fnp-3271	312	2	):	):	PUNCT
fnp-3271	313	1	p.	p.	NOUN
fnp-3271	313	2	938	938	NUM
fnp-3271	313	3	-	-	SYM
fnp-3271	313	4	939	939	NUM
fnp-3271	313	5	.	.	PUNCT
fnp-3271	313	6	30	30	NUM
fnp-3271	313	7	.	.	PUNCT
fnp-3271	314	1	brat	brat	NOUN
fnp-3271	314	2	,	,	PUNCT
fnp-3271	314	3	d.j	d.j	PROPN
fnp-3271	314	4	.	.	PROPN
fnp-3271	314	5	,	,	PUNCT
fnp-3271	314	6	et	et	PROPN
fnp-3271	314	7	al	al	PROPN
fnp-3271	314	8	.	.	PROPN
fnp-3271	314	9	,	,	PUNCT
fnp-3271	314	10	cimpact	cimpact	ADJ
fnp-3271	314	11	-	-	PUNCT
fnp-3271	314	12	now	now	ADV
fnp-3271	314	13	update	update	NOUN
fnp-3271	314	14	3	3	NUM
fnp-3271	314	15	:	:	PUNCT
fnp-3271	314	16	recommended	recommend	VERB
fnp-3271	314	17	diagnostic	diagnostic	ADJ
fnp-3271	314	18	criteria	criterion	NOUN
fnp-3271	314	19	for	for	ADP
fnp-3271	314	20	"	"	PUNCT
fnp-3271	314	21	diffuse	diffuse	VERB
fnp-3271	314	22	astrocytic	astrocytic	ADJ
fnp-3271	314	23	glioma	glioma	NOUN
fnp-3271	314	24	,	,	PUNCT
fnp-3271	314	25	idh	idh	NOUN
fnp-3271	314	26	-	-	PUNCT
fnp-3271	314	27	wildtype	wildtype	NOUN
fnp-3271	314	28	,	,	PUNCT
fnp-3271	314	29	with	with	ADP
fnp-3271	314	30	molecular	molecular	ADJ
fnp-3271	314	31	features	feature	NOUN
fnp-3271	314	32	of	of	ADP
fnp-3271	314	33	glioblastoma	glioblastoma	NOUN
fnp-3271	314	34	,	,	PUNCT
fnp-3271	314	35	who	who	PRON
fnp-3271	314	36	grade	grade	VERB
fnp-3271	314	37	iv	iv	NOUN
fnp-3271	314	38	"	"	PUNCT
fnp-3271	314	39	.	.	PUNCT
fnp-3271	315	1	acta	acta	PROPN
fnp-3271	315	2	neuropathol	neuropathol	PROPN
fnp-3271	315	3	,	,	PUNCT
fnp-3271	315	4	2018	2018	NUM
fnp-3271	315	5	.	.	PUNCT
fnp-3271	316	1	136(5	136(5	NUM
fnp-3271	316	2	):	):	PUNCT
fnp-3271	317	1	p.	p.	NOUN
fnp-3271	317	2	805	805	NUM
fnp-3271	317	3	-	-	SYM
fnp-3271	317	4	810	810	NUM
fnp-3271	317	5	.	.	PUNCT
fnp-3271	317	6	31	31	NUM
fnp-3271	317	7	.	.	X
fnp-3271	318	1	tesileanu	tesileanu	PROPN
fnp-3271	318	2	,	,	PUNCT
fnp-3271	318	3	c.m.s	c.m.s	PROPN
fnp-3271	318	4	.	.	PUNCT
fnp-3271	318	5	,	,	PUNCT
fnp-3271	318	6	et	et	PROPN
fnp-3271	318	7	al	al	PROPN
fnp-3271	318	8	.	.	PROPN
fnp-3271	318	9	,	,	PUNCT
fnp-3271	318	10	survival	survival	NOUN
fnp-3271	318	11	of	of	ADP
fnp-3271	318	12	diffuse	diffuse	PROPN
fnp-3271	318	13	astrocytic	astrocytic	ADJ
fnp-3271	318	14	glioma	glioma	NOUN
fnp-3271	318	15	,	,	PUNCT
fnp-3271	318	16	idh1/2	idh1/2	NOUN
fnp-3271	318	17	wildtype	wildtype	NOUN
fnp-3271	318	18	,	,	PUNCT
fnp-3271	318	19	with	with	ADP
fnp-3271	318	20	molecular	molecular	ADJ
fnp-3271	318	21	features	feature	NOUN
fnp-3271	318	22	of	of	ADP
fnp-3271	318	23	glioblastoma	glioblastoma	NOUN
fnp-3271	318	24	,	,	PUNCT
fnp-3271	318	25	who	who	PRON
fnp-3271	318	26	grade	grade	VERB
fnp-3271	318	27	iv	iv	PRON
fnp-3271	318	28	:	:	PUNCT
fnp-3271	318	29	a	a	DET
fnp-3271	318	30	confirmation	confirmation	NOUN
fnp-3271	318	31	of	of	ADP
fnp-3271	318	32	the	the	DET
fnp-3271	318	33	cimpact	cimpact	ADJ
fnp-3271	318	34	-	-	PUNCT
fnp-3271	318	35	now	now	ADV
fnp-3271	318	36	criteria	criterion	NOUN
fnp-3271	318	37	.	.	PUNCT
fnp-3271	319	1	neuro	neuro	PROPN
fnp-3271	319	2	oncol	oncol	PROPN
fnp-3271	319	3	,	,	PUNCT
fnp-3271	319	4	2020	2020	NUM
fnp-3271	319	5	.	.	PUNCT
fnp-3271	320	1	22(4	22(4	NUM
fnp-3271	320	2	):	):	PUNCT
fnp-3271	321	1	p.	p.	NOUN
fnp-3271	321	2	515	515	NUM
fnp-3271	321	3	-	-	SYM
fnp-3271	321	4	523	523	NUM
fnp-3271	321	5	.	.	PUNCT
fnp-3271	321	6	32	32	NUM
fnp-3271	321	7	.	.	X
fnp-3271	322	1	berzero	berzero	PROPN
fnp-3271	322	2	,	,	PUNCT
fnp-3271	322	3	g.	g.	PROPN
fnp-3271	322	4	,	,	PUNCT
fnp-3271	322	5	et	et	PROPN
fnp-3271	322	6	al	al	PROPN
fnp-3271	322	7	.	.	PROPN
fnp-3271	322	8	,	,	PUNCT
fnp-3271	322	9	idh	idh	NOUN
fnp-3271	322	10	-	-	PUNCT
fnp-3271	322	11	wildtype	wildtype	NOUN
fnp-3271	322	12	lower	low	ADJ
fnp-3271	322	13	grade	grade	NOUN
fnp-3271	322	14	diffuse	diffuse	NOUN
fnp-3271	322	15	gliomas	glioma	NOUN
fnp-3271	322	16	:	:	PUNCT
fnp-3271	322	17	the	the	DET
fnp-3271	322	18	importance	importance	NOUN
fnp-3271	322	19	of	of	ADP
fnp-3271	322	20	histological	histological	ADJ
fnp-3271	322	21	grade	grade	NOUN
fnp-3271	322	22	and	and	CCONJ
fnp-3271	322	23	molecular	molecular	ADJ
fnp-3271	322	24	assessment	assessment	NOUN
fnp-3271	322	25	for	for	ADP
fnp-3271	322	26	prognostic	prognostic	ADJ
fnp-3271	322	27	stratification	stratification	NOUN
fnp-3271	322	28	.	.	PUNCT
fnp-3271	323	1	neuro	neuro	PROPN
fnp-3271	323	2	oncol	oncol	PROPN
fnp-3271	323	3	,	,	PUNCT
fnp-3271	323	4	2020	2020	NUM
fnp-3271	323	5	.	.	PUNCT
fnp-3271	324	1	33	33	NUM
fnp-3271	324	2	.	.	PUNCT
fnp-3271	324	3	deng	deng	PROPN
fnp-3271	324	4	,	,	PUNCT
fnp-3271	324	5	m.y	m.y	PROPN
fnp-3271	324	6	.	.	PROPN
fnp-3271	324	7	,	,	PUNCT
fnp-3271	324	8	et	et	PROPN
fnp-3271	324	9	al	al	PROPN
fnp-3271	324	10	.	.	PROPN
fnp-3271	324	11	,	,	PUNCT
fnp-3271	324	12	diffuse	diffuse	PROPN
fnp-3271	324	13	glioneuronal	glioneuronal	ADJ
fnp-3271	324	14	tumour	tumour	NOUN
fnp-3271	324	15	with	with	ADP
fnp-3271	324	16	oligodendroglioma	oligodendroglioma	ADJ
fnp-3271	324	17	-	-	PUNCT
fnp-3271	324	18	like	like	ADJ
fnp-3271	324	19	features	feature	NOUN
fnp-3271	324	20	and	and	CCONJ
fnp-3271	324	21	nuclear	nuclear	ADJ
fnp-3271	324	22	clusters	cluster	NOUN
fnp-3271	324	23	(	(	PUNCT
fnp-3271	324	24	dgonc	dgonc	PROPN
fnp-3271	324	25	)	)	PUNCT
fnp-3271	324	26	a	a	DET
fnp-3271	324	27	molecularly	molecularly	ADV
fnp-3271	324	28	defined	define	VERB
fnp-3271	324	29	glioneuronal	glioneuronal	ADJ
fnp-3271	324	30	cns	cns	NOUN
fnp-3271	324	31	tumour	tumour	NOUN
fnp-3271	324	32	class	class	NOUN
fnp-3271	324	33	displaying	display	VERB
fnp-3271	324	34	recurrent	recurrent	ADJ
fnp-3271	324	35	monosomy	monosomy	NOUN
fnp-3271	324	36	14	14	NUM
fnp-3271	324	37	.	.	PUNCT
fnp-3271	324	38	neuropathol	neuropathol	PROPN
fnp-3271	324	39	appl	appl	PROPN
fnp-3271	324	40	neurobiol	neurobiol	PROPN
fnp-3271	324	41	,	,	PUNCT
fnp-3271	324	42	2020	2020	NUM
fnp-3271	324	43	.	.	PUNCT
fnp-3271	325	1	46(5	46(5	NOUN
fnp-3271	325	2	):	):	PUNCT
fnp-3271	326	1	p.	p.	NOUN
fnp-3271	326	2	422	422	NUM
fnp-3271	326	3	-	-	SYM
fnp-3271	326	4	430	430	NUM
fnp-3271	326	5	.	.	PUNCT
fnp-3271	327	1	34	34	NUM
fnp-3271	327	2	.	.	PUNCT
fnp-3271	328	1	thomas	thomas	PROPN
fnp-3271	328	2	,	,	PUNCT
fnp-3271	328	3	c.	c.	PROPN
fnp-3271	328	4	,	,	PUNCT
fnp-3271	328	5	et	et	PROPN
fnp-3271	328	6	al	al	PROPN
fnp-3271	328	7	.	.	PROPN
fnp-3271	328	8	,	,	PUNCT
fnp-3271	328	9	desmoplastic	desmoplastic	ADJ
fnp-3271	328	10	myxoid	myxoid	PROPN
fnp-3271	328	11	tumor	tumor	NOUN
fnp-3271	328	12	,	,	PUNCT
fnp-3271	328	13	smarcb1	smarcb1	NOUN
fnp-3271	328	14	-	-	PUNCT
fnp-3271	328	15	mutant	mutant	NOUN
fnp-3271	328	16	:	:	PUNCT
fnp-3271	328	17	clinical	clinical	ADJ
fnp-3271	328	18	,	,	PUNCT
fnp-3271	328	19	histopathological	histopathological	ADJ
fnp-3271	328	20	and	and	CCONJ
fnp-3271	328	21	molecular	molecular	ADJ
fnp-3271	328	22	characterization	characterization	NOUN
fnp-3271	328	23	of	of	ADP
fnp-3271	328	24	a	a	DET
fnp-3271	328	25	pineal	pineal	NOUN
fnp-3271	328	26	region	region	NOUN
fnp-3271	328	27	tumor	tumor	NOUN
fnp-3271	328	28	encountered	encounter	VERB
fnp-3271	328	29	in	in	ADP
fnp-3271	328	30	adolescents	adolescent	NOUN
fnp-3271	328	31	and	and	CCONJ
fnp-3271	328	32	adults	adult	NOUN
fnp-3271	328	33	.	.	PUNCT
fnp-3271	329	1	acta	acta	PROPN
fnp-3271	329	2	neuropathol	neuropathol	PROPN
fnp-3271	329	3	,	,	PUNCT
fnp-3271	329	4	2020	2020	NUM
fnp-3271	329	5	.	.	PUNCT
fnp-3271	330	1	139(2	139(2	NUM
fnp-3271	330	2	):	):	PUNCT
fnp-3271	330	3	p.	p.	NOUN
fnp-3271	330	4	277	277	NUM
fnp-3271	330	5	-	-	SYM
fnp-3271	330	6	286	286	NUM
fnp-3271	330	7	.	.	PUNCT
fnp-3271	331	1	35	35	NUM
fnp-3271	331	2	.	.	PUNCT
fnp-3271	332	1	chen	chen	PROPN
fnp-3271	332	2	,	,	PUNCT
fnp-3271	332	3	c.c.l	c.c.l	PROPN
fnp-3271	332	4	.	.	PROPN
fnp-3271	332	5	,	,	PUNCT
fnp-3271	332	6	et	et	PROPN
fnp-3271	332	7	al	al	PROPN
fnp-3271	332	8	.	.	PROPN
fnp-3271	332	9	,	,	PUNCT
fnp-3271	332	10	histone	histone	PROPN
fnp-3271	332	11	h3.3g34	h3.3g34	NOUN
fnp-3271	332	12	-	-	PUNCT
fnp-3271	332	13	mutant	mutant	ADJ
fnp-3271	332	14	interneuron	interneuron	NOUN
fnp-3271	332	15	progenitors	progenitor	NOUN
fnp-3271	332	16	co	co	ADJ
fnp-3271	332	17	-	-	ADJ
fnp-3271	332	18	opt	opt	ADJ
fnp-3271	332	19	pdgfra	pdgfra	NOUN
fnp-3271	332	20	for	for	ADP
fnp-3271	332	21	gliomagenesis	gliomagenesis	NOUN
fnp-3271	332	22	.	.	PUNCT
fnp-3271	333	1	cell	cell	NOUN
fnp-3271	333	2	,	,	PUNCT
fnp-3271	333	3	2020	2020	NUM
fnp-3271	333	4	.	.	PUNCT
fnp-3271	334	1	183(6	183(6	NUM
fnp-3271	334	2	):	):	PUNCT
fnp-3271	334	3	p.	p.	NOUN
fnp-3271	334	4	1617	1617	NUM
fnp-3271	334	5	-	-	SYM
fnp-3271	334	6	1633	1633	NUM
fnp-3271	334	7	e22	e22	NOUN
fnp-3271	334	8	.	.	PUNCT
fnp-3271	335	1	36	36	NUM
fnp-3271	335	2	.	.	PUNCT
fnp-3271	336	1	michealraj	michealraj	PROPN
fnp-3271	336	2	,	,	PUNCT
fnp-3271	336	3	k.a	k.a	PROPN
fnp-3271	336	4	.	.	PROPN
fnp-3271	336	5	,	,	PUNCT
fnp-3271	336	6	et	et	PROPN
fnp-3271	336	7	al	al	PROPN
fnp-3271	336	8	.	.	PROPN
fnp-3271	336	9	,	,	PUNCT
fnp-3271	336	10	metabolic	metabolic	NOUN
fnp-3271	336	11	regulation	regulation	NOUN
fnp-3271	336	12	of	of	ADP
fnp-3271	336	13	the	the	DET
fnp-3271	336	14	epigenome	epigenome	NOUN
fnp-3271	336	15	drives	drive	VERB
fnp-3271	336	16	lethal	lethal	ADJ
fnp-3271	336	17	infantile	infantile	ADJ
fnp-3271	336	18	ependymoma	ependymoma	NOUN
fnp-3271	336	19	.	.	PUNCT
fnp-3271	337	1	cell	cell	NOUN
fnp-3271	337	2	,	,	PUNCT
fnp-3271	337	3	2020	2020	NUM
fnp-3271	337	4	.	.	PUNCT
fnp-3271	338	1	181(6	181(6	NUM
fnp-3271	338	2	):	):	PUNCT
fnp-3271	338	3	p.	p.	NOUN
fnp-3271	338	4	1329	1329	NUM
fnp-3271	338	5	-	-	SYM
fnp-3271	338	6	1345	1345	NUM
fnp-3271	338	7	e24	e24	NOUN
fnp-3271	338	8	.	.	PROPN
fnp-3271	339	1	37	37	NUM
fnp-3271	339	2	.	.	PUNCT
fnp-3271	340	1	bongaarts	bongaart	NOUN
fnp-3271	340	2	,	,	PUNCT
fnp-3271	340	3	a.	a.	NOUN
fnp-3271	340	4	,	,	PUNCT
fnp-3271	340	5	et	et	PROPN
fnp-3271	340	6	al	al	PROPN
fnp-3271	340	7	.	.	PROPN
fnp-3271	340	8	,	,	PUNCT
fnp-3271	340	9	dysregulation	dysregulation	NOUN
fnp-3271	340	10	of	of	ADP
fnp-3271	340	11	the	the	DET
fnp-3271	340	12	mmp	mmp	PROPN
fnp-3271	340	13	/	/	SYM
fnp-3271	340	14	timp	timp	PROPN
fnp-3271	340	15	proteolytic	proteolytic	ADJ
fnp-3271	340	16	system	system	NOUN
fnp-3271	340	17	in	in	ADP
fnp-3271	340	18	subependymal	subependymal	ADJ
fnp-3271	340	19	giant	giant	ADJ
fnp-3271	340	20	cell	cell	NOUN
fnp-3271	340	21	astrocytomas	astrocytoma	NOUN
fnp-3271	340	22	in	in	ADP
fnp-3271	340	23	patients	patient	NOUN
fnp-3271	340	24	with	with	ADP
fnp-3271	340	25	tuberous	tuberous	ADJ
fnp-3271	340	26	sclerosis	sclerosis	NOUN
fnp-3271	340	27	complex	complex	NOUN
fnp-3271	340	28	:	:	PUNCT
fnp-3271	340	29	modulation	modulation	NOUN
fnp-3271	340	30	of	of	ADP
fnp-3271	340	31	mmp	mmp	PROPN
fnp-3271	340	32	by	by	ADP
fnp-3271	340	33	microrna-320d	microrna-320d	PROPN
fnp-3271	340	34	in	in	ADP
fnp-3271	340	35	vitro	vitro	X
fnp-3271	340	36	.	.	PUNCT
fnp-3271	341	1	j	j	PROPN
fnp-3271	341	2	neuropathol	neuropathol	PROPN
fnp-3271	341	3	exp	exp	PROPN
fnp-3271	341	4	neurol	neurol	PROPN
fnp-3271	341	5	,	,	PUNCT
fnp-3271	341	6	2020	2020	NUM
fnp-3271	341	7	.	.	PUNCT
fnp-3271	342	1	79(7	79(7	NUM
fnp-3271	342	2	):	):	PUNCT
fnp-3271	342	3	p.	p.	NOUN
fnp-3271	342	4	777	777	NUM
fnp-3271	342	5	-	-	PUNCT
fnp-3271	342	6	790	790	NUM
fnp-3271	342	7	.	.	PUNCT
fnp-3271	343	1	38	38	NUM
fnp-3271	343	2	.	.	PUNCT
fnp-3271	344	1	dodgshun	dodgshun	PROPN
fnp-3271	344	2	,	,	PUNCT
fnp-3271	344	3	a.j	a.j	PROPN
fnp-3271	344	4	.	.	PROPN
fnp-3271	344	5	,	,	PUNCT
fnp-3271	344	6	et	et	PROPN
fnp-3271	344	7	al	al	PROPN
fnp-3271	344	8	.	.	PROPN
fnp-3271	344	9	,	,	PUNCT
fnp-3271	344	10	germline	germline	NOUN
fnp-3271	344	11	-	-	PUNCT
fnp-3271	344	12	driven	drive	VERB
fnp-3271	344	13	replication	replication	NOUN
fnp-3271	344	14	repair	repair	NOUN
fnp-3271	344	15	-	-	PUNCT
fnp-3271	344	16	deficient	deficient	ADJ
fnp-3271	344	17	high	high	ADJ
fnp-3271	344	18	-	-	PUNCT
fnp-3271	344	19	grade	grade	NOUN
fnp-3271	344	20	gliomas	glioma	NOUN
fnp-3271	344	21	exhibit	exhibit	VERB
fnp-3271	344	22	unique	unique	ADJ
fnp-3271	344	23	hypomethylation	hypomethylation	NOUN
fnp-3271	344	24	patterns	pattern	NOUN
fnp-3271	344	25	.	.	PUNCT
fnp-3271	345	1	acta	acta	PROPN
fnp-3271	345	2	neuropathol	neuropathol	PROPN
fnp-3271	345	3	,	,	PUNCT
fnp-3271	345	4	2020	2020	NUM
fnp-3271	345	5	.	.	PUNCT
fnp-3271	346	1	140(5	140(5	NUM
fnp-3271	346	2	):	):	PUNCT
fnp-3271	347	1	p.	p.	NOUN
fnp-3271	347	2	765	765	NUM
fnp-3271	347	3	-	-	SYM
fnp-3271	347	4	776	776	NUM
fnp-3271	347	5	.	.	NOUN
fnp-3271	347	6	39	39	NUM
fnp-3271	347	7	.	.	PUNCT
fnp-3271	348	1	yu	yu	PROPN
fnp-3271	348	2	,	,	PUNCT
fnp-3271	348	3	k.	k.	PROPN
fnp-3271	348	4	,	,	PUNCT
fnp-3271	348	5	et	et	PROPN
fnp-3271	348	6	al	al	PROPN
fnp-3271	348	7	.	.	PROPN
fnp-3271	348	8	,	,	PUNCT
fnp-3271	348	9	pik3ca	pik3ca	AUX
fnp-3271	348	10	variants	variant	NOUN
fnp-3271	348	11	selectively	selectively	ADV
fnp-3271	348	12	initiate	initiate	VERB
fnp-3271	348	13	brain	brain	NOUN
fnp-3271	348	14	hyperactivity	hyperactivity	NOUN
fnp-3271	348	15	during	during	ADP
fnp-3271	348	16	gliomagenesis	gliomagenesis	NOUN
fnp-3271	348	17	.	.	PUNCT
fnp-3271	349	1	nature	nature	NOUN
fnp-3271	349	2	,	,	PUNCT
fnp-3271	349	3	2020	2020	NUM
fnp-3271	349	4	.	.	PUNCT
fnp-3271	350	1	578(7793	578(7793	NUM
fnp-3271	350	2	):	):	PUNCT
fnp-3271	350	3	p.	p.	NOUN
fnp-3271	350	4	166	166	NUM
fnp-3271	350	5	-	-	SYM
fnp-3271	350	6	171	171	NUM
fnp-3271	350	7	.	.	PUNCT
fnp-3271	350	8	40	40	NUM
fnp-3271	350	9	.	.	PUNCT
fnp-3271	351	1	monje	monje	PROPN
fnp-3271	351	2	,	,	PUNCT
fnp-3271	351	3	m.	m.	NOUN
fnp-3271	351	4	,	,	PUNCT
fnp-3271	351	5	et	et	PROPN
fnp-3271	351	6	al	al	PROPN
fnp-3271	351	7	.	.	PROPN
fnp-3271	351	8	,	,	PUNCT
fnp-3271	351	9	roadmap	roadmap	NOUN
fnp-3271	351	10	for	for	ADP
fnp-3271	351	11	the	the	DET
fnp-3271	351	12	emerging	emerge	VERB
fnp-3271	351	13	field	field	NOUN
fnp-3271	351	14	of	of	ADP
fnp-3271	351	15	cancer	cancer	NOUN
fnp-3271	351	16	neuroscience	neuroscience	NOUN
fnp-3271	351	17	.	.	PUNCT
fnp-3271	352	1	cell	cell	NOUN
fnp-3271	352	2	,	,	PUNCT
fnp-3271	352	3	2020	2020	NUM
fnp-3271	352	4	.	.	PUNCT
fnp-3271	353	1	181(2	181(2	NUM
fnp-3271	353	2	):	):	PUNCT
fnp-3271	353	3	p.	p.	NOUN
fnp-3271	353	4	219	219	NUM
fnp-3271	353	5	-	-	SYM
fnp-3271	353	6	222	222	NUM
fnp-3271	353	7	.	.	PUNCT
fnp-3271	353	8	41	41	NUM
fnp-3271	353	9	.	.	PUNCT
fnp-3271	354	1	caruso	caruso	PROPN
fnp-3271	354	2	,	,	PUNCT
fnp-3271	354	3	f.p	f.p	PROPN
fnp-3271	354	4	.	.	PROPN
fnp-3271	354	5	,	,	PUNCT
fnp-3271	354	6	et	et	PROPN
fnp-3271	354	7	al	al	PROPN
fnp-3271	354	8	.	.	PROPN
fnp-3271	354	9	,	,	PUNCT
fnp-3271	354	10	a	a	DET
fnp-3271	354	11	map	map	NOUN
fnp-3271	354	12	of	of	ADP
fnp-3271	354	13	tumor	tumor	NOUN
fnp-3271	354	14	-	-	PUNCT
fnp-3271	354	15	host	host	NOUN
fnp-3271	354	16	interactions	interaction	NOUN
fnp-3271	354	17	in	in	ADP
fnp-3271	354	18	glioma	glioma	NOUN
fnp-3271	354	19	at	at	ADP
fnp-3271	354	20	single	single	ADJ
fnp-3271	354	21	-	-	PUNCT
fnp-3271	354	22	cell	cell	NOUN
fnp-3271	354	23	resolution	resolution	NOUN
fnp-3271	354	24	.	.	PUNCT
fnp-3271	355	1	gigascience	gigascience	NOUN
fnp-3271	355	2	,	,	PUNCT
fnp-3271	355	3	2020	2020	NUM
fnp-3271	355	4	.	.	PUNCT
fnp-3271	356	1	9(10	9(10	NUM
fnp-3271	356	2	)	)	PUNCT
fnp-3271	356	3	.	.	PUNCT
fnp-3271	357	1	42	42	NUM
fnp-3271	357	2	.	.	PUNCT
fnp-3271	357	3	voisin	voisin	PROPN
fnp-3271	357	4	,	,	PUNCT
fnp-3271	357	5	m.r	m.r	PROPN
fnp-3271	357	6	.	.	PROPN
fnp-3271	357	7	,	,	PUNCT
fnp-3271	357	8	et	et	PROPN
fnp-3271	357	9	al	al	PROPN
fnp-3271	357	10	.	.	PROPN
fnp-3271	357	11	,	,	PUNCT
fnp-3271	357	12	brain	brain	NOUN
fnp-3271	357	13	tumors	tumor	NOUN
fnp-3271	357	14	and	and	CCONJ
fnp-3271	357	15	covid-19	covid-19	PROPN
fnp-3271	357	16	:	:	PUNCT
fnp-3271	357	17	the	the	DET
fnp-3271	357	18	patient	patient	NOUN
fnp-3271	357	19	and	and	CCONJ
fnp-3271	357	20	caregiver	caregiver	NOUN
fnp-3271	357	21	experience	experience	NOUN
fnp-3271	357	22	.	.	PUNCT
fnp-3271	358	1	neurooncol	neurooncol	PROPN
fnp-3271	358	2	adv	adv	PROPN
fnp-3271	358	3	,	,	PUNCT
fnp-3271	358	4	2020	2020	NUM
fnp-3271	358	5	.	.	PUNCT
fnp-3271	359	1	2(1	2(1	NUM
fnp-3271	359	2	):	):	PUNCT
fnp-3271	359	3	p.	p.	NOUN
fnp-3271	359	4	vdaa104	vdaa104	PROPN
fnp-3271	359	5	.	.	PUNCT
fnp-3271	360	1	43	43	NUM
fnp-3271	360	2	.	.	PUNCT
fnp-3271	361	1	mehta	mehta	PROPN
fnp-3271	361	2	,	,	PUNCT
fnp-3271	361	3	v.	v.	PROPN
fnp-3271	361	4	,	,	PUNCT
fnp-3271	361	5	et	et	PROPN
fnp-3271	361	6	al	al	PROPN
fnp-3271	361	7	.	.	PROPN
fnp-3271	361	8	,	,	PUNCT
fnp-3271	361	9	case	case	NOUN
fnp-3271	361	10	fatality	fatality	NOUN
fnp-3271	361	11	rate	rate	NOUN
fnp-3271	361	12	of	of	ADP
fnp-3271	361	13	cancer	cancer	NOUN
fnp-3271	361	14	patients	patient	NOUN
fnp-3271	361	15	with	with	ADP
fnp-3271	361	16	covid-19	covid-19	PROPN
fnp-3271	361	17	in	in	ADP
fnp-3271	361	18	a	a	DET
fnp-3271	361	19	new	new	PROPN
fnp-3271	361	20	york	york	PROPN
fnp-3271	361	21	hospital	hospital	NOUN
fnp-3271	361	22	system	system	NOUN
fnp-3271	361	23	.	.	PUNCT
fnp-3271	362	1	cancer	cancer	NOUN
fnp-3271	362	2	discov	discov	NOUN
fnp-3271	362	3	,	,	PUNCT
fnp-3271	362	4	2020	2020	NUM
fnp-3271	362	5	.	.	PUNCT
fnp-3271	363	1	10(7	10(7	NUM
fnp-3271	363	2	):	):	PUNCT
fnp-3271	363	3	p.	p.	NOUN
fnp-3271	363	4	935	935	NUM
fnp-3271	363	5	-	-	SYM
fnp-3271	363	6	941	941	NUM
fnp-3271	363	7	.	.	PUNCT
fnp-3271	364	1	44	44	NUM
fnp-3271	364	2	.	.	PUNCT
fnp-3271	365	1	mohile	mohile	PROPN
fnp-3271	365	2	,	,	PUNCT
fnp-3271	365	3	n.a	n.a	PROPN
fnp-3271	365	4	.	.	PROPN
fnp-3271	365	5	,	,	PUNCT
fnp-3271	365	6	et	et	PROPN
fnp-3271	365	7	al	al	PROPN
fnp-3271	365	8	.	.	PROPN
fnp-3271	365	9	,	,	PUNCT
fnp-3271	365	10	urgent	urgent	ADJ
fnp-3271	365	11	considerations	consideration	NOUN
fnp-3271	365	12	for	for	ADP
fnp-3271	365	13	the	the	DET
fnp-3271	365	14	neuro	neuro	NOUN
fnp-3271	365	15	-	-	PUNCT
fnp-3271	365	16	oncologic	oncologic	NOUN
fnp-3271	365	17	treatment	treatment	NOUN
fnp-3271	365	18	of	of	ADP
fnp-3271	365	19	patients	patient	NOUN
fnp-3271	365	20	with	with	ADP
fnp-3271	365	21	gliomas	glioma	NOUN
fnp-3271	365	22	during	during	ADP
fnp-3271	365	23	the	the	DET
fnp-3271	365	24	covid-19	covid-19	PROPN
fnp-3271	365	25	pandemic	pandemic	NOUN
fnp-3271	365	26	.	.	PUNCT
fnp-3271	366	1	neuro	neuro	PROPN
fnp-3271	366	2	oncol	oncol	PROPN
fnp-3271	366	3	,	,	PUNCT
fnp-3271	366	4	2020	2020	NUM
fnp-3271	366	5	.	.	PUNCT
fnp-3271	367	1	45	45	NUM
fnp-3271	367	2	.	.	PUNCT
fnp-3271	367	3	henriksen	henriksen	PROPN
fnp-3271	367	4	,	,	PUNCT
fnp-3271	367	5	j.	j.	PROPN
fnp-3271	367	6	,	,	PUNCT
fnp-3271	367	7	et	et	PROPN
fnp-3271	367	8	al	al	PROPN
fnp-3271	367	9	.	.	PROPN
fnp-3271	367	10	,	,	PUNCT
fnp-3271	367	11	rapid	rapid	ADJ
fnp-3271	367	12	validation	validation	NOUN
fnp-3271	367	13	of	of	ADP
fnp-3271	367	14	telepathology	telepathology	NOUN
fnp-3271	367	15	by	by	ADP
fnp-3271	367	16	an	an	DET
fnp-3271	367	17	academic	academic	ADJ
fnp-3271	367	18	neuropathology	neuropathology	NOUN
fnp-3271	367	19	practice	practice	NOUN
fnp-3271	367	20	during	during	ADP
fnp-3271	367	21	the	the	DET
fnp-3271	367	22	covid-19	covid-19	PROPN
fnp-3271	367	23	pandemic	pandemic	NOUN
fnp-3271	367	24	.	.	PUNCT
fnp-3271	368	1	arch	arch	ADJ
fnp-3271	368	2	pathol	pathol	NOUN
fnp-3271	368	3	lab	lab	NOUN
fnp-3271	368	4	med	me	VERB
fnp-3271	368	5	,	,	PUNCT
fnp-3271	368	6	2020	2020	NUM
fnp-3271	368	7	.	.	PUNCT
fnp-3271	369	1	144(11	144(11	NUM
fnp-3271	369	2	):	):	PUNCT
fnp-3271	369	3	p.	p.	NOUN
fnp-3271	369	4	1311	1311	NUM
fnp-3271	369	5	-	-	SYM
fnp-3271	369	6	1320	1320	NUM
fnp-3271	369	7	.	.	PUNCT
fnp-3271	370	1	46	46	NUM
fnp-3271	370	2	.	.	PUNCT
fnp-3271	370	3	hanna	hanna	PROPN
fnp-3271	370	4	,	,	PUNCT
fnp-3271	370	5	m.g	m.g	PROPN
fnp-3271	370	6	.	.	PROPN
fnp-3271	370	7	,	,	PUNCT
fnp-3271	370	8	et	et	PROPN
fnp-3271	370	9	al	al	PROPN
fnp-3271	370	10	.	.	PROPN
fnp-3271	370	11	,	,	PUNCT
fnp-3271	370	12	validation	validation	NOUN
fnp-3271	370	13	of	of	ADP
fnp-3271	370	14	a	a	DET
fnp-3271	370	15	digital	digital	ADJ
fnp-3271	370	16	pathology	pathology	NOUN
fnp-3271	370	17	system	system	NOUN
fnp-3271	370	18	including	include	VERB
fnp-3271	370	19	remote	remote	ADJ
fnp-3271	370	20	review	review	NOUN
fnp-3271	370	21	during	during	ADP
fnp-3271	370	22	the	the	DET
fnp-3271	370	23	covid-19	covid-19	PROPN
fnp-3271	370	24	pandemic	pandemic	NOUN
fnp-3271	370	25	.	.	PUNCT
fnp-3271	371	1	mod	mod	PROPN
fnp-3271	371	2	pathol	pathol	PROPN
fnp-3271	371	3	,	,	PUNCT
fnp-3271	371	4	2020	2020	NUM
fnp-3271	371	5	.	.	PUNCT
fnp-3271	372	1	33(11	33(11	NUM
fnp-3271	372	2	):	):	PUNCT
fnp-3271	372	3	p.	p.	NOUN
fnp-3271	372	4	2115	2115	NUM
fnp-3271	372	5	-	-	PUNCT
fnp-3271	372	6	2127	2127	NUM
fnp-3271	372	7	.	.	PUNCT
fnp-3271	373	1	47	47	NUM
fnp-3271	373	2	.	.	PUNCT
fnp-3271	374	1	stathonikos	stathonikos	PROPN
fnp-3271	374	2	,	,	PUNCT
fnp-3271	374	3	n.	n.	PROPN
fnp-3271	374	4	,	,	PUNCT
fnp-3271	374	5	et	et	PROPN
fnp-3271	374	6	al	al	PROPN
fnp-3271	374	7	.	.	PROPN
fnp-3271	374	8	,	,	PUNCT
fnp-3271	374	9	digital	digital	ADJ
fnp-3271	374	10	pathology	pathology	NOUN
fnp-3271	374	11	in	in	ADP
fnp-3271	374	12	the	the	DET
fnp-3271	374	13	time	time	NOUN
fnp-3271	374	14	of	of	ADP
fnp-3271	374	15	corona	corona	NOUN
fnp-3271	374	16	.	.	PUNCT
fnp-3271	375	1	j	j	PROPN
fnp-3271	375	2	clin	clin	PROPN
fnp-3271	375	3	pathol	pathol	PROPN
fnp-3271	375	4	,	,	PUNCT
fnp-3271	375	5	2020	2020	NUM
fnp-3271	375	6	.	.	PUNCT
fnp-3271	376	1	73(11	73(11	NUM
fnp-3271	376	2	):	):	PUNCT
fnp-3271	376	3	p.	p.	NOUN
fnp-3271	376	4	706	706	NUM
fnp-3271	376	5	-	-	SYM
fnp-3271	376	6	712	712	NUM
fnp-3271	376	7	.	.	PUNCT
fnp-3271	377	1	48	48	NUM
fnp-3271	377	2	.	.	PUNCT
fnp-3271	378	1	williams	williams	PROPN
fnp-3271	378	2	,	,	PUNCT
fnp-3271	378	3	b.j	b.j	PROPN
fnp-3271	378	4	.	.	PROPN
fnp-3271	378	5	,	,	PUNCT
fnp-3271	378	6	et	et	PROPN
fnp-3271	378	7	al	al	PROPN
fnp-3271	378	8	.	.	PROPN
fnp-3271	378	9	,	,	PUNCT
fnp-3271	378	10	guidance	guidance	NOUN
fnp-3271	378	11	for	for	ADP
fnp-3271	378	12	remote	remote	ADJ
fnp-3271	378	13	reporting	reporting	NOUN
fnp-3271	378	14	of	of	ADP
fnp-3271	378	15	digital	digital	ADJ
fnp-3271	378	16	pathology	pathology	NOUN
fnp-3271	378	17	slides	slide	VERB
fnp-3271	378	18	during	during	ADP
fnp-3271	378	19	periods	period	NOUN
fnp-3271	378	20	of	of	ADP
fnp-3271	378	21	exceptional	exceptional	ADJ
fnp-3271	378	22	service	service	NOUN
fnp-3271	378	23	pressure	pressure	NOUN
fnp-3271	378	24	:	:	PUNCT
fnp-3271	378	25	an	an	DET
fnp-3271	378	26	emergency	emergency	NOUN
fnp-3271	378	27	response	response	NOUN
fnp-3271	378	28	from	from	ADP
fnp-3271	378	29	the	the	DET
fnp-3271	378	30	uk	uk	PROPN
fnp-3271	378	31	royal	royal	PROPN
fnp-3271	378	32	college	college	NOUN
fnp-3271	378	33	of	of	ADP
fnp-3271	378	34	pathologists	pathologist	NOUN
fnp-3271	378	35	.	.	PUNCT
fnp-3271	379	1	j	j	PROPN
fnp-3271	379	2	pathol	pathol	NOUN
fnp-3271	379	3	inform	inform	NOUN
fnp-3271	379	4	,	,	PUNCT
fnp-3271	379	5	2020	2020	NUM
fnp-3271	379	6	.	.	PUNCT
fnp-3271	380	1	11	11	NUM
fnp-3271	380	2	:	:	PUNCT
fnp-3271	380	3	p.	p.	NOUN
fnp-3271	380	4	12	12	NUM
fnp-3271	380	5	.	.	PUNCT
fnp-3271	380	6	49	49	NUM
fnp-3271	380	7	.	.	PUNCT
fnp-3271	381	1	cimadamore	cimadamore	PROPN
fnp-3271	381	2	,	,	PUNCT
fnp-3271	381	3	a.	a.	PROPN
fnp-3271	381	4	,	,	PUNCT
fnp-3271	381	5	et	et	PROPN
fnp-3271	381	6	al	al	PROPN
fnp-3271	381	7	.	.	PROPN
fnp-3271	381	8	,	,	PUNCT
fnp-3271	381	9	digital	digital	ADJ
fnp-3271	381	10	pathology	pathology	NOUN
fnp-3271	381	11	and	and	CCONJ
fnp-3271	381	12	covid-19	covid-19	PROPN
fnp-3271	381	13	and	and	CCONJ
fnp-3271	381	14	future	future	ADJ
fnp-3271	381	15	crises	crisis	NOUN
fnp-3271	381	16	:	:	PUNCT
fnp-3271	381	17	pathologists	pathologist	NOUN
fnp-3271	381	18	can	can	AUX
fnp-3271	381	19	safely	safely	ADV
fnp-3271	381	20	diagnose	diagnose	VERB
fnp-3271	381	21	cases	case	NOUN
fnp-3271	381	22	from	from	ADP
fnp-3271	381	23	home	home	NOUN
fnp-3271	381	24	using	use	VERB
fnp-3271	381	25	a	a	DET
fnp-3271	381	26	consumer	consumer	NOUN
fnp-3271	381	27	monitor	monitor	NOUN
fnp-3271	381	28	and	and	CCONJ
fnp-3271	381	29	a	a	DET
fnp-3271	381	30	mini	mini	ADJ
fnp-3271	381	31	pc	pc	NOUN
fnp-3271	381	32	.	.	PUNCT
fnp-3271	382	1	j	j	PROPN
fnp-3271	382	2	clin	clin	PROPN
fnp-3271	382	3	pathol	pathol	PROPN
fnp-3271	382	4	,	,	PUNCT
fnp-3271	382	5	2020	2020	NUM
fnp-3271	382	6	.	.	PUNCT
fnp-3271	383	1	73(11	73(11	NUM
fnp-3271	383	2	):	):	PUNCT
fnp-3271	383	3	p.	p.	NOUN
fnp-3271	383	4	695	695	NUM
fnp-3271	383	5	-	-	SYM
fnp-3271	383	6	696	696	NUM
fnp-3271	383	7	.	.	X
fnp-3271	384	1	50	50	NUM
fnp-3271	384	2	.	.	X
fnp-3271	384	3	parker	parker	PROPN
fnp-3271	384	4	,	,	PUNCT
fnp-3271	384	5	e.u	e.u	PROPN
fnp-3271	384	6	.	.	PROPN
fnp-3271	384	7	,	,	PUNCT
fnp-3271	384	8	o.	o.	PROPN
fnp-3271	384	9	chang	chang	PROPN
fnp-3271	384	10	,	,	PUNCT
fnp-3271	384	11	and	and	CCONJ
fnp-3271	384	12	l.	l.	PROPN
fnp-3271	384	13	koch	koch	PROPN
fnp-3271	384	14	,	,	PUNCT
fnp-3271	384	15	remote	remote	ADJ
fnp-3271	384	16	anatomic	anatomic	ADJ
fnp-3271	384	17	pathology	pathology	NOUN
fnp-3271	384	18	medical	medical	ADJ
fnp-3271	384	19	student	student	NOUN
fnp-3271	384	20	education	education	NOUN
fnp-3271	384	21	in	in	ADP
fnp-3271	384	22	washington	washington	PROPN
fnp-3271	384	23	state	state	PROPN
fnp-3271	384	24	.	.	PUNCT
fnp-3271	385	1	am	be	AUX
fnp-3271	385	2	j	j	PROPN
fnp-3271	385	3	clin	clin	PROPN
fnp-3271	385	4	pathol	pathol	NOUN
fnp-3271	385	5	,	,	PUNCT
fnp-3271	385	6	2020	2020	NUM
fnp-3271	385	7	.	.	PUNCT
fnp-3271	386	1	154(5	154(5	NUM
fnp-3271	386	2	):	):	PUNCT
fnp-3271	387	1	p.	p.	NOUN
fnp-3271	387	2	585	585	NUM
fnp-3271	387	3	-	-	SYM
fnp-3271	387	4	591	591	NUM
fnp-3271	387	5	.	.	PUNCT
fnp-3271	388	1	51	51	NUM
fnp-3271	388	2	.	.	PUNCT
fnp-3271	388	3	mukhopadhyay	mukhopadhyay	NOUN
fnp-3271	388	4	,	,	PUNCT
fnp-3271	388	5	s.	s.	PROPN
fnp-3271	388	6	,	,	PUNCT
fnp-3271	388	7	et	et	PROPN
fnp-3271	388	8	al	al	PROPN
fnp-3271	388	9	.	.	PROPN
fnp-3271	388	10	,	,	PUNCT
fnp-3271	388	11	leveraging	leverage	VERB
fnp-3271	388	12	technology	technology	NOUN
fnp-3271	388	13	for	for	ADP
fnp-3271	388	14	remote	remote	ADJ
fnp-3271	388	15	learning	learning	NOUN
fnp-3271	388	16	in	in	ADP
fnp-3271	388	17	the	the	DET
fnp-3271	388	18	era	era	NOUN
fnp-3271	388	19	of	of	ADP
fnp-3271	388	20	covid-19	covid-19	PROPN
fnp-3271	388	21	and	and	CCONJ
fnp-3271	388	22	social	social	ADJ
fnp-3271	388	23	distancing	distancing	NOUN
fnp-3271	388	24	.	.	PUNCT
fnp-3271	389	1	arch	arch	ADJ
fnp-3271	389	2	pathol	pathol	NOUN
fnp-3271	389	3	lab	lab	NOUN
fnp-3271	389	4	med	me	VERB
fnp-3271	389	5	,	,	PUNCT
fnp-3271	389	6	2020	2020	NUM
fnp-3271	389	7	.	.	PUNCT
fnp-3271	390	1	144(9	144(9	NUM
fnp-3271	390	2	):	):	PUNCT
fnp-3271	390	3	p.	p.	NOUN
fnp-3271	390	4	1027	1027	NUM
fnp-3271	390	5	-	-	SYM
fnp-3271	390	6	1036	1036	NUM
fnp-3271	390	7	.	.	PUNCT
fnp-3271	391	1	52	52	NUM
fnp-3271	391	2	.	.	PUNCT
fnp-3271	391	3	albeniz	albeniz	PROPN
fnp-3271	391	4	,	,	PUNCT
fnp-3271	391	5	e.	e.	PROPN
fnp-3271	391	6	,	,	PUNCT
fnp-3271	391	7	et	et	PROPN
fnp-3271	391	8	al	al	PROPN
fnp-3271	391	9	.	.	PROPN
fnp-3271	391	10	,	,	PUNCT
fnp-3271	391	11	stay	stay	VERB
fnp-3271	391	12	connected	connected	ADJ
fnp-3271	391	13	and	and	CCONJ
fnp-3271	391	14	up	up	ADP
fnp-3271	391	15	to	to	ADP
fnp-3271	391	16	date	date	NOUN
fnp-3271	391	17	.	.	PUNCT
fnp-3271	392	1	gi	gi	VERB
fnp-3271	392	2	meetings	meeting	NOUN
fnp-3271	392	3	and	and	CCONJ
fnp-3271	392	4	seminars	seminar	NOUN
fnp-3271	392	5	and	and	CCONJ
fnp-3271	392	6	the	the	DET
fnp-3271	392	7	covid-19	covid-19	PROPN
fnp-3271	392	8	pandemic	pandemic	NOUN
fnp-3271	392	9	.	.	PUNCT
fnp-3271	393	1	tech	tech	PROPN
fnp-3271	393	2	innov	innov	PROPN
fnp-3271	393	3	gastrointest	gastrointest	PROPN
fnp-3271	393	4	endosc	endosc	NOUN
fnp-3271	393	5	,	,	PUNCT
fnp-3271	393	6	2020	2020	NUM
fnp-3271	393	7	.	.	PUNCT
fnp-3271	394	1	53	53	NUM
fnp-3271	394	2	.	.	PUNCT
fnp-3271	394	3	bakouny	bakouny	PROPN
fnp-3271	394	4	,	,	PUNCT
fnp-3271	394	5	z.	z.	PROPN
fnp-3271	394	6	,	,	PUNCT
fnp-3271	394	7	et	et	PROPN
fnp-3271	394	8	al	al	PROPN
fnp-3271	394	9	.	.	PROPN
fnp-3271	394	10	,	,	PUNCT
fnp-3271	394	11	covid-19	covid-19	PROPN
fnp-3271	394	12	and	and	CCONJ
fnp-3271	394	13	cancer	cancer	NOUN
fnp-3271	394	14	:	:	PUNCT
fnp-3271	394	15	current	current	ADJ
fnp-3271	394	16	challenges	challenge	NOUN
fnp-3271	394	17	and	and	CCONJ
fnp-3271	394	18	perspectives	perspective	NOUN
fnp-3271	394	19	.	.	PUNCT
fnp-3271	395	1	cancer	cancer	NOUN
fnp-3271	395	2	cell	cell	NOUN
fnp-3271	395	3	,	,	PUNCT
fnp-3271	395	4	2020	2020	NUM
fnp-3271	395	5	.	.	PUNCT
fnp-3271	396	1	38(5	38(5	NUM
fnp-3271	396	2	):	):	PUNCT
fnp-3271	396	3	p.	p.	NOUN
fnp-3271	396	4	629	629	NUM
fnp-3271	396	5	-	-	SYM
fnp-3271	396	6	646	646	NUM
fnp-3271	396	7	.	.	PUNCT
fnp-3271	397	1	54	54	NUM
fnp-3271	397	2	.	.	PUNCT
fnp-3271	398	1	kruger	kruger	PROPN
fnp-3271	398	2	,	,	PUNCT
fnp-3271	398	3	j.	j.	PROPN
fnp-3271	398	4	and	and	CCONJ
fnp-3271	398	5	d.	d.	PROPN
fnp-3271	398	6	dunning	dunning	NOUN
fnp-3271	398	7	,	,	PUNCT
fnp-3271	398	8	unskilled	unskilled	ADJ
fnp-3271	398	9	and	and	CCONJ
fnp-3271	398	10	unaware	unaware	ADJ
fnp-3271	398	11	of	of	ADP
fnp-3271	398	12	it	it	PRON
fnp-3271	398	13	:	:	PUNCT
fnp-3271	398	14	how	how	SCONJ
fnp-3271	398	15	difficulties	difficulty	NOUN
fnp-3271	398	16	in	in	ADP
fnp-3271	398	17	recognizing	recognize	VERB
fnp-3271	398	18	one	one	PRON
fnp-3271	398	19	's	's	PART
fnp-3271	398	20	own	own	ADJ
fnp-3271	398	21	incompetence	incompetence	NOUN
fnp-3271	398	22	lead	lead	NOUN
fnp-3271	398	23	to	to	ADP
fnp-3271	398	24	inflated	inflated	ADJ
fnp-3271	398	25	self	self	NOUN
fnp-3271	398	26	-	-	PUNCT
fnp-3271	398	27	assessments	assessment	NOUN
fnp-3271	398	28	.	.	PUNCT
fnp-3271	399	1	j	j	PROPN
fnp-3271	399	2	pers	per	VERB
fnp-3271	399	3	soc	soc	PROPN
fnp-3271	399	4	psychol	psychol	NOUN
fnp-3271	399	5	,	,	PUNCT
fnp-3271	399	6	1999	1999	NUM
fnp-3271	399	7	.	.	PUNCT
fnp-3271	400	1	77(6	77(6	NUM
fnp-3271	400	2	):	):	PUNCT
fnp-3271	400	3	p.	p.	NOUN
fnp-3271	400	4	1121	1121	NUM
fnp-3271	400	5	-	-	SYM
fnp-3271	400	6	34	34	NUM
fnp-3271	400	7	.	.	PUNCT
fnp-3271	401	1	55	55	NUM
fnp-3271	401	2	.	.	PUNCT
fnp-3271	402	1	stichel	stichel	PROPN
fnp-3271	402	2	,	,	PUNCT
fnp-3271	402	3	d.	d.	PROPN
fnp-3271	402	4	,	,	PUNCT
fnp-3271	402	5	et	et	PROPN
fnp-3271	402	6	al	al	PROPN
fnp-3271	402	7	.	.	PROPN
fnp-3271	402	8	,	,	PUNCT
fnp-3271	402	9	accurate	accurate	ADJ
fnp-3271	402	10	calling	call	VERB
fnp-3271	402	11	of	of	ADP
fnp-3271	402	12	kiaa1549	kiaa1549	PROPN
fnp-3271	402	13	-	-	PUNCT
fnp-3271	402	14	braf	braf	NOUN
fnp-3271	402	15	fusions	fusion	NOUN
fnp-3271	402	16	from	from	ADP
fnp-3271	402	17	dna	dna	NOUN
fnp-3271	402	18	of	of	ADP
fnp-3271	402	19	human	human	ADJ
fnp-3271	402	20	brain	brain	NOUN
fnp-3271	402	21	tumours	tumour	NOUN
fnp-3271	402	22	using	use	VERB
fnp-3271	402	23	methylation	methylation	NOUN
fnp-3271	402	24	array	array	NOUN
fnp-3271	402	25	-	-	PUNCT
fnp-3271	402	26	based	base	VERB
fnp-3271	402	27	copy	copy	NOUN
fnp-3271	402	28	number	number	NOUN
fnp-3271	402	29	and	and	CCONJ
fnp-3271	402	30	gene	gene	NOUN
fnp-3271	402	31	panel	panel	NOUN
fnp-3271	402	32	sequencing	sequence	VERB
fnp-3271	402	33	data	datum	NOUN
fnp-3271	402	34	.	.	PUNCT
fnp-3271	403	1	neuropathol	neuropathol	PROPN
fnp-3271	403	2	appl	appl	PROPN
fnp-3271	403	3	neurobiol	neurobiol	PROPN
fnp-3271	403	4	,	,	PUNCT
fnp-3271	403	5	2020	2020	NUM
fnp-3271	403	6	.	.	PUNCT
fnp-3271	404	1	56	56	NUM
fnp-3271	404	2	.	.	X
fnp-3271	404	3	deng	deng	PROPN
fnp-3271	404	4	,	,	PUNCT
fnp-3271	404	5	m.y	m.y	PROPN
fnp-3271	404	6	.	.	PROPN
fnp-3271	404	7	,	,	PUNCT
fnp-3271	404	8	et	et	PROPN
fnp-3271	404	9	al	al	PROPN
fnp-3271	404	10	.	.	PROPN
fnp-3271	404	11	,	,	PUNCT
fnp-3271	404	12	molecularly	molecularly	ADV
fnp-3271	404	13	defined	define	VERB
fnp-3271	404	14	diffuse	diffuse	NOUN
fnp-3271	404	15	leptomeningeal	leptomeningeal	ADJ
fnp-3271	404	16	glioneuronal	glioneuronal	ADJ
fnp-3271	404	17	tumor	tumor	NOUN
fnp-3271	404	18	(	(	PUNCT
fnp-3271	404	19	dlgnt	dlgnt	NUM
fnp-3271	404	20	)	)	PUNCT
fnp-3271	404	21	comprises	comprise	VERB
fnp-3271	404	22	two	two	NUM
fnp-3271	404	23	subgroups	subgroup	NOUN
fnp-3271	404	24	with	with	ADP
fnp-3271	404	25	distinct	distinct	ADJ
fnp-3271	404	26	clinical	clinical	ADJ
fnp-3271	404	27	and	and	CCONJ
fnp-3271	404	28	genetic	genetic	ADJ
fnp-3271	404	29	features	feature	NOUN
fnp-3271	404	30	.	.	PUNCT
fnp-3271	405	1	acta	acta	PROPN
fnp-3271	405	2	neuropathol	neuropathol	PROPN
fnp-3271	405	3	,	,	PUNCT
fnp-3271	405	4	2018	2018	NUM
fnp-3271	405	5	.	.	PUNCT
fnp-3271	406	1	136(2	136(2	NUM
fnp-3271	406	2	):	):	PUNCT
fnp-3271	407	1	p.	p.	NOUN
fnp-3271	407	2	239	239	NUM
fnp-3271	407	3	-	-	SYM
fnp-3271	407	4	253	253	NUM
fnp-3271	407	5	.	.	PUNCT
fnp-3271	408	1	copyright	copyright	NOUN
fnp-3271	408	2	:	:	PUNCT
fnp-3271	408	3	©	©	PROPN
fnp-3271	408	4	2021	2021	NUM
fnp-3271	408	5	the	the	DET
fnp-3271	408	6	author(s	author(s	NOUN
fnp-3271	408	7	)	)	PUNCT
fnp-3271	408	8	.	.	PUNCT
fnp-3271	409	1	this	this	PRON
fnp-3271	409	2	is	be	AUX
fnp-3271	409	3	an	an	DET
fnp-3271	409	4	open	open	ADJ
fnp-3271	409	5	access	access	NOUN
fnp-3271	409	6	article	article	NOUN
fnp-3271	409	7	distributed	distribute	VERB
fnp-3271	409	8	under	under	ADP
fnp-3271	409	9	the	the	DET
fnp-3271	409	10	terms	term	NOUN
fnp-3271	409	11	of	of	ADP
fnp-3271	409	12	the	the	DET
fnp-3271	409	13	creative	creative	ADJ
fnp-3271	409	14	commons	common	NOUN
fnp-3271	409	15	attribution	attribution	NOUN
fnp-3271	409	16	4.0	4.0	NUM
fnp-3271	409	17	international	international	ADJ
fnp-3271	409	18	license	license	NOUN
fnp-3271	409	19	(	(	PUNCT
fnp-3271	409	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3271	409	21	)	)	PUNCT
fnp-3271	409	22	,	,	PUNCT
fnp-3271	409	23	which	which	PRON
fnp-3271	409	24	permits	permit	VERB
fnp-3271	409	25	unrestricted	unrestricted	ADJ
fnp-3271	409	26	use	use	NOUN
fnp-3271	409	27	,	,	PUNCT
fnp-3271	409	28	distribution	distribution	NOUN
fnp-3271	409	29	,	,	PUNCT
fnp-3271	409	30	and	and	CCONJ
fnp-3271	409	31	reproduction	reproduction	NOUN
fnp-3271	409	32	in	in	ADP
fnp-3271	409	33	any	any	DET
fnp-3271	409	34	medium	medium	NOUN
fnp-3271	409	35	,	,	PUNCT
fnp-3271	409	36	provided	provide	VERB
fnp-3271	409	37	the	the	DET
fnp-3271	409	38	original	original	ADJ
fnp-3271	409	39	author	author	NOUN
fnp-3271	409	40	and	and	CCONJ
fnp-3271	409	41	source	source	NOUN
fnp-3271	409	42	are	be	AUX
fnp-3271	409	43	credited	credit	VERB
fnp-3271	409	44	,	,	PUNCT
fnp-3271	409	45	a	a	DET
fnp-3271	409	46	link	link	NOUN
fnp-3271	409	47	to	to	ADP
fnp-3271	409	48	the	the	DET
fnp-3271	409	49	creative	creative	ADJ
fnp-3271	409	50	commons	common	NOUN
fnp-3271	409	51	license	license	NOUN
fnp-3271	409	52	is	be	AUX
fnp-3271	409	53	provided	provide	VERB
fnp-3271	409	54	,	,	PUNCT
fnp-3271	409	55	and	and	CCONJ
fnp-3271	409	56	any	any	DET
fnp-3271	409	57	changes	change	NOUN
fnp-3271	409	58	are	be	AUX
fnp-3271	409	59	indicated	indicate	VERB
fnp-3271	409	60	.	.	PUNCT
fnp-3271	410	1	the	the	DET
fnp-3271	410	2	creative	creative	ADJ
fnp-3271	410	3	commons	common	NOUN
fnp-3271	410	4	public	public	ADJ
fnp-3271	410	5	domain	domain	NOUN
fnp-3271	410	6	dedication	dedication	NOUN
fnp-3271	410	7	waiver	waiver	NOUN
fnp-3271	410	8	(	(	PUNCT
fnp-3271	410	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3271	410	10	)	)	PUNCT
fnp-3271	410	11	applies	apply	VERB
fnp-3271	410	12	to	to	ADP
fnp-3271	410	13	the	the	DET
fnp-3271	410	14	data	datum	NOUN
fnp-3271	410	15	made	make	VERB
fnp-3271	410	16	available	available	ADJ
fnp-3271	410	17	in	in	ADP
fnp-3271	410	18	this	this	DET
fnp-3271	410	19	article	article	NOUN
fnp-3271	410	20	,	,	PUNCT
fnp-3271	410	21	unless	unless	SCONJ
fnp-3271	410	22	otherwise	otherwise	ADV
fnp-3271	410	23	stated	state	VERB
fnp-3271	410	24	.	.	PUNCT