id	sid	tid	token	lemma	pos
fnp-3317	1	1	neurodegeneration	neurodegeneration	NOUN
fnp-3317	1	2	:	:	PUNCT
fnp-3317	1	3	2021	2021	NUM
fnp-3317	1	4	update	update	NOUN
fnp-3317	1	5	feel	feel	VERB
fnp-3317	1	6	free	free	ADJ
fnp-3317	1	7	to	to	PART
fnp-3317	1	8	add	add	VERB
fnp-3317	1	9	comments	comment	NOUN
fnp-3317	1	10	by	by	ADP
fnp-3317	1	11	clicking	click	VERB
fnp-3317	1	12	these	these	DET
fnp-3317	1	13	icons	icon	NOUN
fnp-3317	1	14	on	on	ADP
fnp-3317	1	15	the	the	DET
fnp-3317	1	16	sidebar	sidebar	NOUN
fnp-3317	1	17	free	free	ADJ
fnp-3317	1	18	neuropathology	neuropathology	NOUN
fnp-3317	1	19	2:9	2:9	NUM
fnp-3317	1	20	(	(	PUNCT
fnp-3317	1	21	2021	2021	NUM
fnp-3317	1	22	)	)	PUNCT
fnp-3317	1	23	review	review	NOUN
fnp-3317	1	24	neurodegeneration	neurodegeneration	NOUN
fnp-3317	1	25	:	:	PUNCT
fnp-3317	1	26	2021	2021	NUM
fnp-3317	1	27	update	update	NOUN
fnp-3317	1	28	john	john	PROPN
fnp-3317	1	29	f.	f.	PROPN
fnp-3317	1	30	crary	crary	PROPN
fnp-3317	1	31	neuropathology	neuropathology	PROPN
fnp-3317	1	32	brain	brain	PROPN
fnp-3317	1	33	bank	bank	PROPN
fnp-3317	1	34	&	&	CCONJ
fnp-3317	1	35	research	research	PROPN
fnp-3317	1	36	core	core	NOUN
fnp-3317	1	37	,	,	PUNCT
fnp-3317	1	38	department	department	NOUN
fnp-3317	1	39	of	of	ADP
fnp-3317	1	40	pathology	pathology	PROPN
fnp-3317	1	41	,	,	PUNCT
fnp-3317	1	42	nash	nash	PROPN
fnp-3317	1	43	family	family	PROPN
fnp-3317	1	44	department	department	PROPN
fnp-3317	1	45	of	of	ADP
fnp-3317	1	46	neuroscience	neuroscience	NOUN
fnp-3317	1	47	,	,	PUNCT
fnp-3317	1	48	ronald	ronald	PROPN
fnp-3317	1	49	m.	m.	PROPN
fnp-3317	1	50	loeb	loeb	PROPN
fnp-3317	1	51	center	center	PROPN
fnp-3317	1	52	for	for	ADP
fnp-3317	1	53	alzheimer	alzheimer	PROPN
fnp-3317	1	54	's	's	PART
fnp-3317	1	55	disease	disease	NOUN
fnp-3317	1	56	,	,	PUNCT
fnp-3317	1	57	friedman	friedman	PROPN
fnp-3317	1	58	brain	brain	PROPN
fnp-3317	1	59	institute	institute	PROPN
fnp-3317	1	60	,	,	PUNCT
fnp-3317	1	61	icahn	icahn	PROPN
fnp-3317	1	62	school	school	PROPN
fnp-3317	1	63	of	of	ADP
fnp-3317	1	64	medicine	medicine	NOUN
fnp-3317	1	65	at	at	ADP
fnp-3317	1	66	mount	mount	PROPN
fnp-3317	1	67	sinai	sinai	PROPN
fnp-3317	1	68	,	,	PUNCT
fnp-3317	1	69	new	new	PROPN
fnp-3317	1	70	york	york	PROPN
fnp-3317	1	71	,	,	PUNCT
fnp-3317	1	72	ny	ny	PROPN
fnp-3317	1	73	,	,	PUNCT
fnp-3317	1	74	usa	usa	PROPN
fnp-3317	1	75	corresponding	corresponding	PROPN
fnp-3317	1	76	author	author	NOUN
fnp-3317	1	77	:	:	PUNCT
fnp-3317	1	78	john	john	PROPN
fnp-3317	1	79	f.	f.	PROPN
fnp-3317	1	80	crary	crary	PROPN
fnp-3317	1	81	,	,	PUNCT
fnp-3317	1	82	md	md	PROPN
fnp-3317	1	83	-	-	PUNCT
fnp-3317	1	84	phd	phd	NOUN
fnp-3317	1	85	·	·	PUNCT
fnp-3317	1	86	friedman	friedman	PROPN
fnp-3317	1	87	brain	brain	PROPN
fnp-3317	1	88	institute	institute	PROPN
fnp-3317	1	89	·	·	PUNCT
fnp-3317	1	90	ronald	ronald	PROPN
fnp-3317	1	91	m.	m.	PROPN
fnp-3317	1	92	loeb	loeb	PROPN
fnp-3317	1	93	center	center	PROPN
fnp-3317	1	94	for	for	ADP
fnp-3317	1	95	alzheimer	alzheimer	PROPN
fnp-3317	1	96	’s	’s	PART
fnp-3317	1	97	disease	disease	NOUN
fnp-3317	1	98	·	·	PUNCT
fnp-3317	1	99	icahn	icahn	PROPN
fnp-3317	1	100	school	school	NOUN
fnp-3317	1	101	of	of	ADP
fnp-3317	1	102	medicine	medicine	NOUN
fnp-3317	1	103	at	at	ADP
fnp-3317	1	104	mount	mount	PROPN
fnp-3317	1	105	sinai	sinai	PROPN
fnp-3317	1	106	·	·	PUNCT
fnp-3317	1	107	1	1	NUM
fnp-3317	1	108	gustave	gustave	X
fnp-3317	1	109	l.	l.	PROPN
fnp-3317	1	110	levy	levy	PROPN
fnp-3317	1	111	place	place	PROPN
fnp-3317	1	112	box	box	PROPN
fnp-3317	1	113	1194	1194	NUM
fnp-3317	1	114	·	·	PUNCT
fnp-3317	1	115	new	new	PROPN
fnp-3317	1	116	york	york	PROPN
fnp-3317	1	117	,	,	PUNCT
fnp-3317	1	118	ny	ny	PROPN
fnp-3317	1	119	10029	10029	NUM
fnp-3317	1	120	·	·	PUNCT
fnp-3317	2	1	usa	usa	PROPN
fnp-3317	2	2	john.crary@mountsinai.org	john.crary@mountsinai.org	PROPN
fnp-3317	2	3	submitted	submit	VERB
fnp-3317	2	4	:	:	PUNCT
fnp-3317	2	5	28	28	NUM
fnp-3317	2	6	march	march	NOUN
fnp-3317	2	7	2021	2021	NUM
fnp-3317	2	8	accepted	accept	VERB
fnp-3317	2	9	:	:	PUNCT
fnp-3317	3	1	15	15	NUM
fnp-3317	3	2	april	april	PROPN
fnp-3317	3	3	2021	2021	NUM
fnp-3317	3	4	copyedited	copyedit	VERB
fnp-3317	3	5	by	by	ADP
fnp-3317	3	6	:	:	PUNCT
fnp-3317	3	7	jeffrey	jeffrey	PROPN
fnp-3317	3	8	nirschl	nirschl	PROPN
fnp-3317	3	9	published	publish	VERB
fnp-3317	3	10	:	:	PUNCT
fnp-3317	3	11	21	21	NUM
fnp-3317	3	12	april	april	PROPN
fnp-3317	3	13	2021	2021	NUM
fnp-3317	3	14	https://doi.org/10.17879/freeneuropathology-2021-3317	https://doi.org/10.17879/freeneuropathology-2021-3317	NOUN
fnp-3317	3	15	keywords	keyword	NOUN
fnp-3317	3	16	:	:	PUNCT
fnp-3317	3	17	neurodegeneration	neurodegeneration	NOUN
fnp-3317	3	18	,	,	PUNCT
fnp-3317	3	19	neuropathology	neuropathology	NOUN
fnp-3317	3	20	,	,	PUNCT
fnp-3317	3	21	alzheimer	alzheimer	PROPN
fnp-3317	3	22	disease	disease	NOUN
fnp-3317	3	23	,	,	PUNCT
fnp-3317	3	24	tauopathy	tauopathy	NOUN
fnp-3317	3	25	,	,	PUNCT
fnp-3317	3	26	α	α	NOUN
fnp-3317	3	27	-	-	PUNCT
fnp-3317	3	28	synucleinopathy	synucleinopathy	ADJ
fnp-3317	3	29	,	,	PUNCT
fnp-3317	3	30	chronic	chronic	ADJ
fnp-3317	3	31	traumatic	traumatic	ADJ
fnp-3317	3	32	encephalopathy	encephalopathy	NOUN
fnp-3317	3	33	,	,	PUNCT
fnp-3317	3	34	cryogenic	cryogenic	NOUN
fnp-3317	3	35	electron	electron	NOUN
fnp-3317	3	36	microscopy	microscopy	NOUN
fnp-3317	3	37	,	,	PUNCT
fnp-3317	3	38	proteomics	proteomic	NOUN
fnp-3317	3	39	abstract	abstract	NOUN
fnp-3317	3	40	this	this	DET
fnp-3317	3	41	article	article	NOUN
fnp-3317	3	42	reviews	review	VERB
fnp-3317	3	43	a	a	DET
fnp-3317	3	44	collection	collection	NOUN
fnp-3317	3	45	of	of	ADP
fnp-3317	3	46	manuscripts	manuscript	NOUN
fnp-3317	3	47	in	in	ADP
fnp-3317	3	48	the	the	DET
fnp-3317	3	49	field	field	NOUN
fnp-3317	3	50	of	of	ADP
fnp-3317	3	51	neurodegenerative	neurodegenerative	ADJ
fnp-3317	3	52	disease	disease	NOUN
fnp-3317	3	53	chosen	choose	VERB
fnp-3317	3	54	from	from	ADP
fnp-3317	3	55	what	what	PRON
fnp-3317	3	56	are	be	AUX
fnp-3317	3	57	considered	consider	VERB
fnp-3317	3	58	by	by	ADP
fnp-3317	3	59	the	the	DET
fnp-3317	3	60	author	author	NOUN
fnp-3317	3	61	to	to	PART
fnp-3317	3	62	be	be	AUX
fnp-3317	3	63	among	among	ADP
fnp-3317	3	64	the	the	DET
fnp-3317	3	65	10	10	NUM
fnp-3317	3	66	most	most	ADV
fnp-3317	3	67	important	important	ADJ
fnp-3317	3	68	and	and	CCONJ
fnp-3317	3	69	potentially	potentially	ADV
fnp-3317	3	70	impactful	impactful	ADJ
fnp-3317	3	71	topics	topic	NOUN
fnp-3317	3	72	or	or	CCONJ
fnp-3317	3	73	research	research	NOUN
fnp-3317	3	74	trends	trend	NOUN
fnp-3317	3	75	of	of	ADP
fnp-3317	3	76	2020	2020	NUM
fnp-3317	3	77	relevant	relevant	ADJ
fnp-3317	3	78	to	to	ADP
fnp-3317	3	79	the	the	DET
fnp-3317	3	80	field	field	NOUN
fnp-3317	3	81	of	of	ADP
fnp-3317	3	82	experimental	experimental	ADJ
fnp-3317	3	83	and	and	CCONJ
fnp-3317	3	84	diagnostic	diagnostic	ADJ
fnp-3317	3	85	neuropathology	neuropathology	NOUN
fnp-3317	3	86	.	.	PUNCT
fnp-3317	4	1	a	a	DET
fnp-3317	4	2	deliberate	deliberate	ADJ
fnp-3317	4	3	effort	effort	NOUN
fnp-3317	4	4	was	be	AUX
fnp-3317	4	5	made	make	VERB
fnp-3317	4	6	to	to	PART
fnp-3317	4	7	provide	provide	VERB
fnp-3317	4	8	balance	balance	NOUN
fnp-3317	4	9	among	among	ADP
fnp-3317	4	10	disease	disease	NOUN
fnp-3317	4	11	categories	category	NOUN
fnp-3317	4	12	covered	cover	VERB
fnp-3317	4	13	.	.	PUNCT
fnp-3317	5	1	the	the	DET
fnp-3317	5	2	result	result	NOUN
fnp-3317	5	3	is	be	AUX
fnp-3317	5	4	a	a	DET
fnp-3317	5	5	varied	varied	ADJ
fnp-3317	5	6	selection	selection	NOUN
fnp-3317	5	7	that	that	PRON
fnp-3317	5	8	includes	include	VERB
fnp-3317	5	9	not	not	PART
fnp-3317	5	10	just	just	ADV
fnp-3317	5	11	individual	individual	ADJ
fnp-3317	5	12	papers	paper	NOUN
fnp-3317	5	13	but	but	CCONJ
fnp-3317	5	14	also	also	ADV
fnp-3317	5	15	research	research	VERB
fnp-3317	5	16	topics	topic	NOUN
fnp-3317	5	17	and	and	CCONJ
fnp-3317	5	18	trends	trend	NOUN
fnp-3317	5	19	.	.	PUNCT
fnp-3317	6	1	the	the	DET
fnp-3317	6	2	association	association	NOUN
fnp-3317	6	3	of	of	ADP
fnp-3317	6	4	covid-19	covid-19	PROPN
fnp-3317	6	5	with	with	ADP
fnp-3317	6	6	longer	long	ADJ
fnp-3317	6	7	-	-	PUNCT
fnp-3317	6	8	term	term	NOUN
fnp-3317	6	9	neurological	neurological	ADJ
fnp-3317	6	10	symptoms	symptom	NOUN
fnp-3317	6	11	has	have	AUX
fnp-3317	6	12	launched	launch	VERB
fnp-3317	6	13	a	a	DET
fnp-3317	6	14	research	research	NOUN
fnp-3317	6	15	trend	trend	NOUN
fnp-3317	6	16	fueled	fuel	VERB
fnp-3317	6	17	by	by	ADP
fnp-3317	6	18	speculation	speculation	NOUN
fnp-3317	6	19	that	that	SCONJ
fnp-3317	6	20	the	the	DET
fnp-3317	6	21	sars	sar	NOUN
fnp-3317	6	22	-	-	PUNCT
fnp-3317	6	23	cov-2	cov-2	NOUN
fnp-3317	6	24	might	might	AUX
fnp-3317	6	25	trigger	trigger	VERB
fnp-3317	6	26	neurodegenerative	neurodegenerative	ADJ
fnp-3317	6	27	changes	change	NOUN
fnp-3317	6	28	.	.	PUNCT
fnp-3317	7	1	the	the	DET
fnp-3317	7	2	onslaught	onslaught	NOUN
fnp-3317	7	3	of	of	ADP
fnp-3317	7	4	transcriptomic	transcriptomic	ADJ
fnp-3317	7	5	studies	study	NOUN
fnp-3317	7	6	has	have	AUX
fnp-3317	7	7	begun	begin	VERB
fnp-3317	7	8	to	to	PART
fnp-3317	7	9	give	give	VERB
fnp-3317	7	10	way	way	NOUN
fnp-3317	7	11	to	to	ADP
fnp-3317	7	12	proteomics	proteomic	NOUN
fnp-3317	7	13	,	,	PUNCT
fnp-3317	7	14	with	with	ADP
fnp-3317	7	15	three	three	NUM
fnp-3317	7	16	transformative	transformative	ADJ
fnp-3317	7	17	studies	study	NOUN
fnp-3317	7	18	published	publish	VERB
fnp-3317	7	19	examining	examine	VERB
fnp-3317	7	20	glial	glial	ADJ
fnp-3317	7	21	contributions	contribution	NOUN
fnp-3317	7	22	to	to	ADP
fnp-3317	7	23	alzheimer	alzheimer	PROPN
fnp-3317	7	24	disease	disease	PROPN
fnp-3317	7	25	,	,	PUNCT
fnp-3317	7	26	cerebral	cerebral	ADJ
fnp-3317	7	27	atherosclerosis	atherosclerosis	NOUN
fnp-3317	7	28	in	in	ADP
fnp-3317	7	29	cognitive	cognitive	ADJ
fnp-3317	7	30	decline	decline	NOUN
fnp-3317	7	31	,	,	PUNCT
fnp-3317	7	32	and	and	CCONJ
fnp-3317	7	33	the	the	DET
fnp-3317	7	34	complex	complex	ADJ
fnp-3317	7	35	sequence	sequence	NOUN
fnp-3317	7	36	of	of	ADP
fnp-3317	7	37	post	post	ADJ
fnp-3317	7	38	-	-	ADJ
fnp-3317	7	39	translational	translational	ADJ
fnp-3317	7	40	modifications	modification	NOUN
fnp-3317	7	41	of	of	ADP
fnp-3317	7	42	the	the	DET
fnp-3317	7	43	tau	tau	PROPN
fnp-3317	7	44	protein	protein	NOUN
fnp-3317	7	45	.	.	PUNCT
fnp-3317	8	1	plasma	plasma	NOUN
fnp-3317	8	2	biomarkers	biomarker	NOUN
fnp-3317	8	3	for	for	ADP
fnp-3317	8	4	alzheimer	alzheimer	PROPN
fnp-3317	8	5	disease	disease	NOUN
fnp-3317	8	6	have	have	AUX
fnp-3317	8	7	continued	continue	VERB
fnp-3317	8	8	to	to	PART
fnp-3317	8	9	make	make	VERB
fnp-3317	8	10	rapid	rapid	ADJ
fnp-3317	8	11	advances	advance	NOUN
fnp-3317	8	12	,	,	PUNCT
fnp-3317	8	13	especially	especially	ADV
fnp-3317	8	14	around	around	ADP
fnp-3317	8	15	highly	highly	ADV
fnp-3317	8	16	sensitive	sensitive	ADJ
fnp-3317	8	17	assays	assay	NOUN
fnp-3317	8	18	capable	capable	ADJ
fnp-3317	8	19	of	of	ADP
fnp-3317	8	20	detecting	detect	VERB
fnp-3317	8	21	different	different	ADJ
fnp-3317	8	22	forms	form	NOUN
fnp-3317	8	23	of	of	ADP
fnp-3317	8	24	abnormal	abnormal	ADJ
fnp-3317	8	25	hyperphosphorylated	hyperphosphorylate	VERB
fnp-3317	8	26	tau	tau	NOUN
fnp-3317	8	27	in	in	ADP
fnp-3317	8	28	peripheral	peripheral	ADJ
fnp-3317	8	29	blood	blood	NOUN
fnp-3317	8	30	.	.	PUNCT
fnp-3317	9	1	two	two	NUM
fnp-3317	9	2	studies	study	NOUN
fnp-3317	9	3	using	use	VERB
fnp-3317	9	4	cryo	cryo	NOUN
fnp-3317	9	5	-	-	PUNCT
fnp-3317	9	6	electron	electron	NOUN
fnp-3317	9	7	microscopy	microscopy	NOUN
fnp-3317	9	8	showed	show	VERB
fnp-3317	9	9	the	the	DET
fnp-3317	9	10	power	power	NOUN
fnp-3317	9	11	of	of	ADP
fnp-3317	9	12	the	the	DET
fnp-3317	9	13	approach	approach	NOUN
fnp-3317	9	14	by	by	ADP
fnp-3317	9	15	continuing	continue	VERB
fnp-3317	9	16	to	to	PART
fnp-3317	9	17	elucidate	elucidate	VERB
fnp-3317	9	18	the	the	DET
fnp-3317	9	19	diversity	diversity	NOUN
fnp-3317	9	20	of	of	ADP
fnp-3317	9	21	filamentous	filamentous	ADJ
fnp-3317	9	22	tau	tau	NOUN
fnp-3317	9	23	inclusions	inclusion	NOUN
fnp-3317	9	24	,	,	PUNCT
fnp-3317	9	25	and	and	CCONJ
fnp-3317	9	26	a	a	DET
fnp-3317	9	27	third	third	ADJ
fnp-3317	9	28	study	study	NOUN
fnp-3317	9	29	gave	give	VERB
fnp-3317	9	30	the	the	DET
fnp-3317	9	31	first	first	ADJ
fnp-3317	9	32	glimpse	glimpse	NOUN
fnp-3317	9	33	of	of	ADP
fnp-3317	9	34	α	α	NOUN
fnp-3317	9	35	-	-	PUNCT
fnp-3317	9	36	synuclein	synuclein	NOUN
fnp-3317	9	37	aggregates	aggregate	NOUN
fnp-3317	9	38	at	at	ADP
fnp-3317	9	39	near	near	ADP
fnp-3317	9	40	atomic	atomic	ADJ
fnp-3317	9	41	resolution	resolution	NOUN
fnp-3317	9	42	.	.	PUNCT
fnp-3317	10	1	another	another	DET
fnp-3317	10	2	study	study	NOUN
fnp-3317	10	3	continued	continue	VERB
fnp-3317	10	4	to	to	PART
fnp-3317	10	5	delineate	delineate	VERB
fnp-3317	10	6	how	how	SCONJ
fnp-3317	10	7	different	different	ADJ
fnp-3317	10	8	α	α	ADJ
fnp-3317	10	9	-	-	PUNCT
fnp-3317	10	10	synuclein	synuclein	ADJ
fnp-3317	10	11	conformers	conformer	NOUN
fnp-3317	10	12	(	(	PUNCT
fnp-3317	10	13	“	"	PUNCT
fnp-3317	10	14	strains	strain	NOUN
fnp-3317	10	15	”	"	PUNCT
fnp-3317	10	16	)	)	PUNCT
fnp-3317	10	17	target	target	VERB
fnp-3317	10	18	specific	specific	ADJ
fnp-3317	10	19	brain	brain	NOUN
fnp-3317	10	20	regions	region	NOUN
fnp-3317	10	21	and	and	CCONJ
fnp-3317	10	22	lead	lead	VERB
fnp-3317	10	23	to	to	ADP
fnp-3317	10	24	neurodegeneration	neurodegeneration	NOUN
fnp-3317	10	25	.	.	PUNCT
fnp-3317	11	1	in	in	ADP
fnp-3317	11	2	huntington	huntington	PROPN
fnp-3317	11	3	’s	’s	PART
fnp-3317	11	4	disease	disease	NOUN
fnp-3317	11	5	,	,	PUNCT
fnp-3317	11	6	we	we	PRON
fnp-3317	11	7	saw	see	VERB
fnp-3317	11	8	compelling	compelling	ADJ
fnp-3317	11	9	molecular	molecular	ADJ
fnp-3317	11	10	data	datum	NOUN
fnp-3317	11	11	showing	show	VERB
fnp-3317	11	12	how	how	SCONJ
fnp-3317	11	13	cells	cell	NOUN
fnp-3317	11	14	adapt	adapt	VERB
fnp-3317	11	15	to	to	ADP
fnp-3317	11	16	endoplasmic	endoplasmic	ADJ
fnp-3317	11	17	reticulum	reticulum	NOUN
fnp-3317	11	18	stress	stress	NOUN
fnp-3317	11	19	through	through	ADP
fnp-3317	11	20	the	the	DET
fnp-3317	11	21	unfolded	unfolded	ADJ
fnp-3317	11	22	protein	protein	NOUN
fnp-3317	11	23	response	response	NOUN
fnp-3317	11	24	.	.	PUNCT
fnp-3317	12	1	finally	finally	ADV
fnp-3317	12	2	,	,	PUNCT
fnp-3317	12	3	the	the	DET
fnp-3317	12	4	role	role	NOUN
fnp-3317	12	5	of	of	ADP
fnp-3317	12	6	astrocytes	astrocyte	NOUN
fnp-3317	12	7	in	in	ADP
fnp-3317	12	8	chronic	chronic	ADJ
fnp-3317	12	9	traumatic	traumatic	ADJ
fnp-3317	12	10	encephalopathy	encephalopathy	NOUN
fnp-3317	12	11	has	have	AUX
fnp-3317	12	12	emerged	emerge	VERB
fnp-3317	12	13	as	as	ADP
fnp-3317	12	14	a	a	DET
fnp-3317	12	15	critical	critical	ADJ
fnp-3317	12	16	area	area	NOUN
fnp-3317	12	17	of	of	ADP
fnp-3317	12	18	interest	interest	NOUN
fnp-3317	12	19	.	.	PUNCT
fnp-3317	13	1	introduction	introduction	NOUN
fnp-3317	13	2	in	in	ADP
fnp-3317	13	3	a	a	DET
fnp-3317	13	4	year	year	NOUN
fnp-3317	13	5	like	like	ADP
fnp-3317	13	6	no	no	DET
fnp-3317	13	7	other	other	ADJ
fnp-3317	13	8	,	,	PUNCT
fnp-3317	13	9	experimental	experimental	ADJ
fnp-3317	13	10	neuropathology	neuropathology	NOUN
fnp-3317	13	11	research	research	NOUN
fnp-3317	13	12	in	in	ADP
fnp-3317	13	13	neurodegeneration	neurodegeneration	NOUN
fnp-3317	13	14	persevered	persevere	VERB
fnp-3317	13	15	.	.	PUNCT
fnp-3317	14	1	confronted	confront	VERB
fnp-3317	14	2	with	with	ADP
fnp-3317	14	3	a	a	DET
fnp-3317	14	4	devastating	devastating	ADJ
fnp-3317	14	5	pandemic	pandemic	NOUN
fnp-3317	14	6	,	,	PUNCT
fnp-3317	14	7	we	we	PRON
fnp-3317	14	8	endured	endure	VERB
fnp-3317	14	9	despite	despite	SCONJ
fnp-3317	14	10	shuttered	shuttered	ADJ
fnp-3317	14	11	laboratories	laboratory	NOUN
fnp-3317	14	12	,	,	PUNCT
fnp-3317	14	13	working	work	VERB
fnp-3317	14	14	from	from	ADP
fnp-3317	14	15	home	home	NOUN
fnp-3317	14	16	,	,	PUNCT
fnp-3317	14	17	supply	supply	NOUN
fnp-3317	14	18	shortages	shortage	NOUN
fnp-3317	14	19	,	,	PUNCT
fnp-3317	14	20	the	the	DET
fnp-3317	14	21	loss	loss	NOUN
fnp-3317	14	22	of	of	ADP
fnp-3317	14	23	loved	love	VERB
fnp-3317	14	24	ones	one	NOUN
fnp-3317	14	25	and	and	CCONJ
fnp-3317	14	26	a	a	DET
fnp-3317	14	27	myriad	myriad	NOUN
fnp-3317	14	28	of	of	ADP
fnp-3317	14	29	other	other	ADJ
fnp-3317	14	30	challenges	challenge	NOUN
fnp-3317	14	31	.	.	PUNCT
fnp-3317	15	1	our	our	PRON
fnp-3317	15	2	laboratories	laboratory	NOUN
fnp-3317	15	3	demonstrated	demonstrate	VERB
fnp-3317	15	4	inspiring	inspiring	ADJ
fnp-3317	15	5	resilience	resilience	NOUN
fnp-3317	15	6	,	,	PUNCT
fnp-3317	15	7	adapting	adapt	VERB
fnp-3317	15	8	to	to	ADP
fnp-3317	15	9	the	the	DET
fnp-3317	15	10	new	new	ADJ
fnp-3317	15	11	landscape	landscape	NOUN
fnp-3317	15	12	and	and	CCONJ
fnp-3317	15	13	soldiering	soldiering	NOUN
fnp-3317	15	14	on	on	ADP
fnp-3317	15	15	.	.	PUNCT
fnp-3317	16	1	many	many	ADJ
fnp-3317	16	2	rose	rise	VERB
fnp-3317	16	3	to	to	ADP
fnp-3317	16	4	the	the	DET
fnp-3317	16	5	challenge	challenge	NOUN
fnp-3317	16	6	,	,	PUNCT
fnp-3317	16	7	finding	find	VERB
fnp-3317	16	8	purpose	purpose	NOUN
fnp-3317	16	9	and	and	CCONJ
fnp-3317	16	10	inspiration	inspiration	NOUN
fnp-3317	16	11	in	in	ADP
fnp-3317	16	12	adversity	adversity	NOUN
fnp-3317	16	13	.	.	PUNCT
fnp-3317	17	1	dr	dr	PROPN
fnp-3317	17	2	.	.	PROPN
fnp-3317	17	3	rita	rita	PROPN
fnp-3317	17	4	levy	levy	NOUN
fnp-3317	17	5	montalcini	montalcini	NOUN
fnp-3317	17	6	once	once	ADV
fnp-3317	17	7	said	say	VERB
fnp-3317	17	8	,	,	PUNCT
fnp-3317	17	9	“	"	PUNCT
fnp-3317	17	10	i	i	PRON
fnp-3317	17	11	should	should	AUX
fnp-3317	17	12	thank	thank	VERB
fnp-3317	17	13	mussolini	mussolini	PROPN
fnp-3317	17	14	for	for	ADP
fnp-3317	17	15	having	having	AUX
fnp-3317	17	16	declared	declare	VERB
fnp-3317	17	17	me	i	PRON
fnp-3317	17	18	to	to	PART
fnp-3317	17	19	be	be	AUX
fnp-3317	17	20	of	of	ADP
fnp-3317	17	21	an	an	DET
fnp-3317	17	22	inferior	inferior	ADJ
fnp-3317	17	23	race	race	NOUN
fnp-3317	17	24	.	.	PUNCT
fnp-3317	18	1	this	this	PRON
fnp-3317	18	2	led	lead	VERB
fnp-3317	18	3	me	i	PRON
fnp-3317	18	4	to	to	ADP
fnp-3317	18	5	the	the	DET
fnp-3317	18	6	joy	joy	NOUN
fnp-3317	18	7	of	of	ADP
fnp-3317	18	8	working	work	VERB
fnp-3317	18	9	,	,	PUNCT
fnp-3317	18	10	not	not	PART
fnp-3317	18	11	any	any	PRON
fnp-3317	18	12	more	more	ADV
fnp-3317	18	13	unfortunately	unfortunately	ADV
fnp-3317	18	14	in	in	ADP
fnp-3317	18	15	university	university	NOUN
fnp-3317	18	16	institutes	institutes	NOUN
fnp-3317	18	17	,	,	PUNCT
fnp-3317	18	18	but	but	CCONJ
fnp-3317	18	19	in	in	ADP
fnp-3317	18	20	a	a	DET
fnp-3317	18	21	bedroom	bedroom	NOUN
fnp-3317	18	22	.	.	PUNCT
fnp-3317	18	23	”	"	PUNCT
fnp-3317	19	1	upon	upon	SCONJ
fnp-3317	19	2	completing	complete	VERB
fnp-3317	19	3	this	this	DET
fnp-3317	19	4	review	review	NOUN
fnp-3317	19	5	of	of	ADP
fnp-3317	19	6	just	just	ADV
fnp-3317	19	7	a	a	DET
fnp-3317	19	8	few	few	ADJ
fnp-3317	19	9	of	of	ADP
fnp-3317	19	10	the	the	DET
fnp-3317	19	11	accomplishments	accomplishment	NOUN
fnp-3317	19	12	of	of	ADP
fnp-3317	19	13	the	the	DET
fnp-3317	19	14	past	past	ADJ
fnp-3317	19	15	year	year	NOUN
fnp-3317	19	16	,	,	PUNCT
fnp-3317	19	17	it	it	PRON
fnp-3317	19	18	was	be	AUX
fnp-3317	19	19	clear	clear	ADJ
fnp-3317	19	20	that	that	SCONJ
fnp-3317	19	21	this	this	DET
fnp-3317	19	22	spirit	spirit	NOUN
fnp-3317	19	23	is	be	AUX
fnp-3317	19	24	alive	alive	ADJ
fnp-3317	19	25	,	,	PUNCT
fnp-3317	19	26	the	the	DET
fnp-3317	19	27	same	same	ADJ
fnp-3317	19	28	that	that	PRON
fnp-3317	19	29	compelled	compel	VERB
fnp-3317	19	30	levy	levy	NOUN
fnp-3317	19	31	-	-	PUNCT
fnp-3317	19	32	montalcini	montalcini	NOUN
fnp-3317	19	33	to	to	PART
fnp-3317	19	34	work	work	VERB
fnp-3317	19	35	tirelessly	tirelessly	ADV
fnp-3317	19	36	at	at	ADP
fnp-3317	19	37	home	home	NOUN
fnp-3317	19	38	to	to	PART
fnp-3317	19	39	study	study	VERB
fnp-3317	19	40	chick	chick	NOUN
fnp-3317	19	41	embryos	embryo	NOUN
fnp-3317	19	42	using	use	VERB
fnp-3317	19	43	scalpels	scalpel	NOUN
fnp-3317	19	44	fashioned	fashion	VERB
fnp-3317	19	45	from	from	ADP
fnp-3317	19	46	sewing	sewing	NOUN
fnp-3317	19	47	needles	needle	NOUN
fnp-3317	19	48	.	.	PUNCT
fnp-3317	20	1	the	the	DET
fnp-3317	20	2	spirit	spirit	NOUN
fnp-3317	20	3	could	could	AUX
fnp-3317	20	4	be	be	AUX
fnp-3317	20	5	felt	feel	VERB
fnp-3317	20	6	emanating	emanate	VERB
fnp-3317	20	7	from	from	ADP
fnp-3317	20	8	our	our	PRON
fnp-3317	20	9	colleagues	colleague	NOUN
fnp-3317	20	10	sheltering	shelter	VERB
fnp-3317	20	11	at	at	ADP
fnp-3317	20	12	home	home	NOUN
fnp-3317	20	13	,	,	PUNCT
fnp-3317	20	14	many	many	ADJ
fnp-3317	20	15	also	also	ADV
fnp-3317	20	16	literally	literally	ADV
fnp-3317	20	17	working	work	VERB
fnp-3317	20	18	in	in	ADP
fnp-3317	20	19	their	their	PRON
fnp-3317	20	20	bedrooms	bedroom	NOUN
fnp-3317	20	21	!	!	PUNCT
fnp-3317	21	1	so	so	ADV
fnp-3317	21	2	,	,	PUNCT
fnp-3317	21	3	it	it	PRON
fnp-3317	21	4	is	be	AUX
fnp-3317	21	5	with	with	ADP
fnp-3317	21	6	great	great	ADJ
fnp-3317	21	7	pride	pride	NOUN
fnp-3317	21	8	and	and	CCONJ
fnp-3317	21	9	appreciation	appreciation	NOUN
fnp-3317	21	10	that	that	SCONJ
fnp-3317	21	11	we	we	PRON
fnp-3317	21	12	take	take	VERB
fnp-3317	21	13	this	this	PRON
fnp-3317	21	14	look	look	VERB
fnp-3317	21	15	back	back	ADV
fnp-3317	21	16	and	and	CCONJ
fnp-3317	21	17	celebrate	celebrate	VERB
fnp-3317	21	18	the	the	DET
fnp-3317	21	19	accomplishments	accomplishment	NOUN
fnp-3317	21	20	of	of	ADP
fnp-3317	21	21	our	our	PRON
fnp-3317	21	22	colleagues	colleague	NOUN
fnp-3317	21	23	and	and	CCONJ
fnp-3317	21	24	recognize	recognize	VERB
fnp-3317	21	25	just	just	ADV
fnp-3317	21	26	a	a	DET
fnp-3317	21	27	few	few	ADJ
fnp-3317	21	28	of	of	ADP
fnp-3317	21	29	the	the	DET
fnp-3317	21	30	many	many	ADJ
fnp-3317	21	31	transformative	transformative	ADJ
fnp-3317	21	32	advances	advance	NOUN
fnp-3317	21	33	in	in	ADP
fnp-3317	21	34	2020	2020	NUM
fnp-3317	21	35	.	.	PUNCT
fnp-3317	22	1	the	the	DET
fnp-3317	22	2	pandemic	pandemic	NOUN
fnp-3317	22	3	is	be	AUX
fnp-3317	22	4	a	a	DET
fnp-3317	22	5	reminder	reminder	NOUN
fnp-3317	22	6	that	that	SCONJ
fnp-3317	22	7	substantive	substantive	ADJ
fnp-3317	22	8	scientific	scientific	ADJ
fnp-3317	22	9	progress	progress	NOUN
fnp-3317	22	10	comes	come	VERB
fnp-3317	22	11	with	with	ADP
fnp-3317	22	12	great	great	ADJ
fnp-3317	22	13	human	human	ADJ
fnp-3317	22	14	effort	effort	NOUN
fnp-3317	22	15	and	and	CCONJ
fnp-3317	22	16	rarely	rarely	ADV
fnp-3317	22	17	a	a	DET
fnp-3317	22	18	“	"	PUNCT
fnp-3317	22	19	eureka	eureka	PROPN
fnp-3317	22	20	moment	moment	NOUN
fnp-3317	22	21	.	.	PUNCT
fnp-3317	22	22	”	"	PUNCT
fnp-3317	23	1	here	here	ADV
fnp-3317	23	2	,	,	PUNCT
fnp-3317	23	3	we	we	PRON
fnp-3317	23	4	also	also	ADV
fnp-3317	23	5	highlight	highlight	VERB
fnp-3317	23	6	collaborative	collaborative	ADJ
fnp-3317	23	7	efforts	effort	NOUN
fnp-3317	23	8	,	,	PUNCT
fnp-3317	23	9	research	research	NOUN
fnp-3317	23	10	trends	trend	NOUN
fnp-3317	23	11	,	,	PUNCT
fnp-3317	23	12	groundbreaking	groundbreake	VERB
fnp-3317	23	13	methodologies	methodology	NOUN
fnp-3317	23	14	,	,	PUNCT
fnp-3317	23	15	and	and	CCONJ
fnp-3317	23	16	tools	tool	NOUN
fnp-3317	23	17	.	.	PUNCT
fnp-3317	24	1	a	a	DET
fnp-3317	24	2	concerted	concerted	ADJ
fnp-3317	24	3	effort	effort	NOUN
fnp-3317	24	4	was	be	AUX
fnp-3317	24	5	made	make	VERB
fnp-3317	24	6	to	to	PART
fnp-3317	24	7	seek	seek	VERB
fnp-3317	24	8	out	out	ADP
fnp-3317	24	9	innovations	innovation	NOUN
fnp-3317	24	10	across	across	ADP
fnp-3317	24	11	all	all	DET
fnp-3317	24	12	neurodegenerative	neurodegenerative	ADJ
fnp-3317	24	13	disease	disease	NOUN
fnp-3317	24	14	categories	category	NOUN
fnp-3317	24	15	.	.	PUNCT
fnp-3317	25	1	given	give	VERB
fnp-3317	25	2	the	the	DET
fnp-3317	25	3	readership	readership	NOUN
fnp-3317	25	4	and	and	CCONJ
fnp-3317	25	5	mission	mission	NOUN
fnp-3317	25	6	of	of	ADP
fnp-3317	25	7	this	this	DET
fnp-3317	25	8	journal	journal	NOUN
fnp-3317	25	9	,	,	PUNCT
fnp-3317	25	10	we	we	PRON
fnp-3317	25	11	emphasized	emphasize	VERB
fnp-3317	25	12	pathoanatomical	pathoanatomical	ADJ
fnp-3317	25	13	studies	study	NOUN
fnp-3317	25	14	most	most	ADV
fnp-3317	25	15	relevant	relevant	ADJ
fnp-3317	25	16	to	to	ADP
fnp-3317	25	17	neuropathologists	neuropathologist	NOUN
fnp-3317	25	18	and	and	CCONJ
fnp-3317	25	19	clinical	clinical	ADJ
fnp-3317	25	20	neuroscientists	neuroscientist	NOUN
fnp-3317	25	21	.	.	PUNCT
fnp-3317	26	1	1	1	X
fnp-3317	26	2	.	.	X
fnp-3317	27	1	the	the	DET
fnp-3317	27	2	long	long	ADJ
fnp-3317	27	3	-	-	PUNCT
fnp-3317	27	4	term	term	NOUN
fnp-3317	27	5	neuropathological	neuropathological	ADJ
fnp-3317	27	6	sequelae	sequelae	NOUN
fnp-3317	27	7	of	of	ADP
fnp-3317	27	8	covid-19	covid-19	PROPN
fnp-3317	27	9	over	over	ADP
fnp-3317	27	10	the	the	DET
fnp-3317	27	11	past	past	ADJ
fnp-3317	27	12	year	year	NOUN
fnp-3317	27	13	,	,	PUNCT
fnp-3317	27	14	the	the	DET
fnp-3317	27	15	sars	sar	NOUN
fnp-3317	27	16	-	-	PUNCT
fnp-3317	27	17	cov-2	cov-2	NOUN
fnp-3317	27	18	/	/	SYM
fnp-3317	27	19	covid-19	covid-19	PROPN
fnp-3317	27	20	pandemic	pandemic	NOUN
fnp-3317	27	21	has	have	AUX
fnp-3317	27	22	permeated	permeate	VERB
fnp-3317	27	23	essentially	essentially	ADV
fnp-3317	27	24	every	every	DET
fnp-3317	27	25	aspect	aspect	NOUN
fnp-3317	27	26	of	of	ADP
fnp-3317	27	27	our	our	PRON
fnp-3317	27	28	lives	life	NOUN
fnp-3317	27	29	,	,	PUNCT
fnp-3317	27	30	and	and	CCONJ
fnp-3317	27	31	research	research	NOUN
fnp-3317	27	32	in	in	ADP
fnp-3317	27	33	neurodegenerative	neurodegenerative	ADJ
fnp-3317	27	34	disease	disease	NOUN
fnp-3317	27	35	is	be	AUX
fnp-3317	27	36	no	no	DET
fnp-3317	27	37	exception	exception	NOUN
fnp-3317	27	38	,	,	PUNCT
fnp-3317	27	39	launching	launch	VERB
fnp-3317	27	40	a	a	DET
fnp-3317	27	41	new	new	ADJ
fnp-3317	27	42	,	,	PUNCT
fnp-3317	27	43	albeit	albeit	SCONJ
fnp-3317	27	44	speculative	speculative	ADJ
fnp-3317	27	45	,	,	PUNCT
fnp-3317	27	46	research	research	NOUN
fnp-3317	27	47	trend	trend	NOUN
fnp-3317	27	48	.	.	PUNCT
fnp-3317	28	1	early	early	ADV
fnp-3317	28	2	in	in	ADP
fnp-3317	28	3	the	the	DET
fnp-3317	28	4	pandemic	pandemic	NOUN
fnp-3317	28	5	,	,	PUNCT
fnp-3317	28	6	neuropathologists	neuropathologist	NOUN
fnp-3317	28	7	began	begin	VERB
fnp-3317	28	8	to	to	PART
fnp-3317	28	9	wonder	wonder	VERB
fnp-3317	28	10	about	about	ADP
fnp-3317	28	11	the	the	DET
fnp-3317	28	12	extent	extent	NOUN
fnp-3317	28	13	to	to	PART
fnp-3317	28	14	which	which	PRON
fnp-3317	28	15	covid-19	covid-19	PROPN
fnp-3317	28	16	might	might	AUX
fnp-3317	28	17	impact	impact	VERB
fnp-3317	28	18	brain	brain	NOUN
fnp-3317	28	19	health	health	NOUN
fnp-3317	28	20	.	.	PUNCT
fnp-3317	29	1	theoretically	theoretically	ADV
fnp-3317	29	2	,	,	PUNCT
fnp-3317	29	3	this	this	PRON
fnp-3317	29	4	could	could	AUX
fnp-3317	29	5	be	be	AUX
fnp-3317	29	6	through	through	ADP
fnp-3317	29	7	direct	direct	ADJ
fnp-3317	29	8	neurotropism	neurotropism	NOUN
fnp-3317	29	9	as	as	SCONJ
fnp-3317	29	10	some	some	DET
fnp-3317	29	11	coronaviruses	coronaviruse	NOUN
fnp-3317	29	12	are	be	AUX
fnp-3317	29	13	known	know	VERB
fnp-3317	29	14	to	to	PART
fnp-3317	29	15	cause	cause	VERB
fnp-3317	29	16	encephalitis	encephalitis	NOUN
fnp-3317	29	17	,	,	PUNCT
fnp-3317	29	18	or	or	CCONJ
fnp-3317	29	19	perhaps	perhaps	ADV
fnp-3317	29	20	indirectly	indirectly	ADV
fnp-3317	29	21	through	through	ADP
fnp-3317	29	22	complications	complication	NOUN
fnp-3317	29	23	related	relate	VERB
fnp-3317	29	24	to	to	ADP
fnp-3317	29	25	critical	critical	ADJ
fnp-3317	29	26	illness	illness	NOUN
fnp-3317	29	27	and	and	CCONJ
fnp-3317	29	28	systemic	systemic	ADJ
fnp-3317	29	29	disease	disease	NOUN
fnp-3317	29	30	(	(	PUNCT
fnp-3317	29	31	morgello	morgello	PROPN
fnp-3317	29	32	,	,	PUNCT
fnp-3317	29	33	2020	2020	NUM
fnp-3317	29	34	)	)	PUNCT
fnp-3317	29	35	.	.	PUNCT
fnp-3317	30	1	early	early	ADJ
fnp-3317	30	2	reports	report	NOUN
fnp-3317	30	3	documented	document	VERB
fnp-3317	30	4	encephalitis	encephalitis	NOUN
fnp-3317	30	5	in	in	ADP
fnp-3317	30	6	the	the	DET
fnp-3317	30	7	setting	setting	NOUN
fnp-3317	30	8	of	of	ADP
fnp-3317	30	9	covid-19	covid-19	PROPN
fnp-3317	30	10	(	(	PUNCT
fnp-3317	30	11	reichard	reichard	PROPN
fnp-3317	30	12	et	et	PROPN
fnp-3317	30	13	al	al	PROPN
fnp-3317	30	14	.	.	PROPN
fnp-3317	30	15	,	,	PUNCT
fnp-3317	30	16	2020	2020	NUM
fnp-3317	30	17	)	)	PUNCT
fnp-3317	30	18	,	,	PUNCT
fnp-3317	30	19	but	but	CCONJ
fnp-3317	30	20	sars	sar	NOUN
fnp-3317	30	21	-	-	PUNCT
fnp-3317	30	22	cov-2	cov-2	NOUN
fnp-3317	30	23	encephalitis	encephalitis	NOUN
fnp-3317	30	24	was	be	AUX
fnp-3317	30	25	considered	consider	VERB
fnp-3317	30	26	a	a	DET
fnp-3317	30	27	rare	rare	ADJ
fnp-3317	30	28	event	event	NOUN
fnp-3317	30	29	predominantly	predominantly	ADV
fnp-3317	30	30	restricted	restrict	VERB
fnp-3317	30	31	to	to	ADP
fnp-3317	30	32	susceptible	susceptible	ADJ
fnp-3317	30	33	populations	population	NOUN
fnp-3317	30	34	and	and	CCONJ
fnp-3317	30	35	of	of	ADP
fnp-3317	30	36	modest	modest	ADJ
fnp-3317	30	37	public	public	ADJ
fnp-3317	30	38	health	health	NOUN
fnp-3317	30	39	concern	concern	NOUN
fnp-3317	30	40	.	.	PUNCT
fnp-3317	31	1	larger	large	ADJ
fnp-3317	31	2	autopsy	autopsy	ADJ
fnp-3317	31	3	series	series	NOUN
fnp-3317	31	4	emerged	emerge	VERB
fnp-3317	31	5	,	,	PUNCT
fnp-3317	31	6	highlighting	highlight	VERB
fnp-3317	31	7	infarction	infarction	NOUN
fnp-3317	31	8	and	and	CCONJ
fnp-3317	31	9	microthrombi	microthrombi	NOUN
fnp-3317	31	10	in	in	ADP
fnp-3317	31	11	the	the	DET
fnp-3317	31	12	brain	brain	NOUN
fnp-3317	31	13	in	in	ADP
fnp-3317	31	14	the	the	DET
fnp-3317	31	15	acute	acute	NOUN
fnp-3317	31	16	setting	setting	NOUN
fnp-3317	31	17	(	(	PUNCT
fnp-3317	31	18	figure	figure	NOUN
fnp-3317	31	19	1	1	NUM
fnp-3317	31	20	)	)	PUNCT
fnp-3317	31	21	,	,	PUNCT
fnp-3317	31	22	more	more	ADV
fnp-3317	31	23	commonly	commonly	ADV
fnp-3317	31	24	in	in	ADP
fnp-3317	31	25	hospitalized	hospitalize	VERB
fnp-3317	31	26	patients	patient	NOUN
fnp-3317	31	27	,	,	PUNCT
fnp-3317	31	28	but	but	CCONJ
fnp-3317	31	29	this	this	PRON
fnp-3317	31	30	too	too	ADV
fnp-3317	31	31	was	be	AUX
fnp-3317	31	32	thought	think	VERB
fnp-3317	31	33	to	to	PART
fnp-3317	31	34	be	be	AUX
fnp-3317	31	35	uncommon	uncommon	ADJ
fnp-3317	31	36	(	(	PUNCT
fnp-3317	31	37	bryce	bryce	PROPN
fnp-3317	31	38	et	et	PROPN
fnp-3317	31	39	al	al	PROPN
fnp-3317	31	40	.	.	PROPN
fnp-3317	31	41	,	,	PUNCT
fnp-3317	31	42	2020	2020	NUM
fnp-3317	31	43	)	)	PUNCT
fnp-3317	31	44	.	.	PUNCT
fnp-3317	32	1	nevertheless	nevertheless	ADV
fnp-3317	32	2	,	,	PUNCT
fnp-3317	32	3	researchers	researcher	NOUN
fnp-3317	32	4	began	begin	VERB
fnp-3317	32	5	to	to	PART
fnp-3317	32	6	speculate	speculate	VERB
fnp-3317	32	7	that	that	SCONJ
fnp-3317	32	8	there	there	PRON
fnp-3317	32	9	may	may	AUX
fnp-3317	32	10	be	be	AUX
fnp-3317	32	11	long	long	ADJ
fnp-3317	32	12	-	-	PUNCT
fnp-3317	32	13	term	term	NOUN
fnp-3317	32	14	neurological	neurological	ADJ
fnp-3317	32	15	sequelae	sequelae	NOUN
fnp-3317	32	16	that	that	PRON
fnp-3317	32	17	follow	follow	VERB
fnp-3317	32	18	covid-19	covid-19	PROPN
fnp-3317	32	19	as	as	ADP
fnp-3317	32	20	examples	example	NOUN
fnp-3317	32	21	of	of	ADP
fnp-3317	32	22	post	post	ADJ
fnp-3317	32	23	-	-	ADJ
fnp-3317	32	24	viral	viral	ADJ
fnp-3317	32	25	tauopathy	tauopathy	NOUN
fnp-3317	32	26	and	and	CCONJ
fnp-3317	32	27	neurodegeneration	neurodegeneration	NOUN
fnp-3317	32	28	are	be	AUX
fnp-3317	32	29	well	well	ADV
fnp-3317	32	30	documented	document	VERB
fnp-3317	32	31	and	and	CCONJ
fnp-3317	32	32	now	now	ADV
fnp-3317	32	33	there	there	PRON
fnp-3317	32	34	is	be	VERB
fnp-3317	32	35	increasing	increase	VERB
fnp-3317	32	36	alarm	alarm	NOUN
fnp-3317	32	37	that	that	SCONJ
fnp-3317	32	38	there	there	PRON
fnp-3317	32	39	might	might	AUX
fnp-3317	32	40	be	be	AUX
fnp-3317	32	41	an	an	DET
fnp-3317	32	42	incipient	incipient	ADJ
fnp-3317	32	43	rise	rise	NOUN
fnp-3317	32	44	in	in	ADP
fnp-3317	32	45	neurological	neurological	ADJ
fnp-3317	32	46	complications	complication	NOUN
fnp-3317	32	47	,	,	PUNCT
fnp-3317	32	48	including	include	VERB
fnp-3317	32	49	dementia	dementia	NOUN
fnp-3317	32	50	and	and	CCONJ
fnp-3317	32	51	neurodegeneration	neurodegeneration	NOUN
fnp-3317	32	52	,	,	PUNCT
fnp-3317	32	53	that	that	PRON
fnp-3317	32	54	might	might	AUX
fnp-3317	32	55	follow	follow	VERB
fnp-3317	32	56	the	the	DET
fnp-3317	32	57	pandemic	pandemic	ADJ
fnp-3317	32	58	(	(	PUNCT
fnp-3317	32	59	badrfam	badrfam	PROPN
fnp-3317	32	60	&	&	CCONJ
fnp-3317	32	61	zandifar	zandifar	NOUN
fnp-3317	32	62	,	,	PUNCT
fnp-3317	32	63	2020	2020	NUM
fnp-3317	32	64	)	)	PUNCT
fnp-3317	32	65	.	.	PUNCT
fnp-3317	33	1	figure	figure	NOUN
fnp-3317	33	2	1	1	NUM
fnp-3317	33	3	.	.	PUNCT
fnp-3317	34	1	post	post	ADJ
fnp-3317	34	2	-	-	ADJ
fnp-3317	34	3	mortem	mortem	ADJ
fnp-3317	34	4	findings	finding	NOUN
fnp-3317	34	5	in	in	ADP
fnp-3317	34	6	a	a	DET
fnp-3317	34	7	patient	patient	NOUN
fnp-3317	34	8	with	with	ADP
fnp-3317	34	9	sars	sar	NOUN
fnp-3317	34	10	-	-	PUNCT
fnp-3317	34	11	cov-2	cov-2	NOUN
fnp-3317	34	12	/	/	SYM
fnp-3317	34	13	covid-19	covid-19	PROPN
fnp-3317	34	14	.	.	PUNCT
fnp-3317	35	1	a.	a.	PROPN
fnp-3317	35	2	fresh	fresh	ADJ
fnp-3317	35	3	gross	gross	ADJ
fnp-3317	35	4	image	image	NOUN
fnp-3317	35	5	of	of	ADP
fnp-3317	35	6	a	a	DET
fnp-3317	35	7	right	right	ADJ
fnp-3317	35	8	hemibrain	hemibrain	NOUN
fnp-3317	35	9	from	from	ADP
fnp-3317	35	10	a	a	DET
fnp-3317	35	11	68	68	NUM
fnp-3317	35	12	male	male	NOUN
fnp-3317	35	13	with	with	ADP
fnp-3317	35	14	covid-19	covid-19	PROPN
fnp-3317	35	15	showing	show	VERB
fnp-3317	35	16	diffuse	diffuse	NOUN
fnp-3317	35	17	swelling	swelling	NOUN
fnp-3317	35	18	and	and	CCONJ
fnp-3317	35	19	leptomeningeal	leptomeningeal	ADJ
fnp-3317	35	20	hemorrhage	hemorrhage	NOUN
fnp-3317	35	21	.	.	PUNCT
fnp-3317	36	1	b.	b.	PROPN
fnp-3317	36	2	fixed	fix	VERB
fnp-3317	36	3	right	right	ADV
fnp-3317	36	4	hemibrain	hemibrain	ADV
fnp-3317	36	5	from	from	ADP
fnp-3317	36	6	the	the	DET
fnp-3317	36	7	same	same	ADJ
fnp-3317	36	8	patient	patient	NOUN
fnp-3317	36	9	showing	show	VERB
fnp-3317	36	10	acute	acute	NOUN
fnp-3317	36	11	and	and	CCONJ
fnp-3317	36	12	subacute	subacute	VERB
fnp-3317	36	13	infarction	infarction	NOUN
fnp-3317	36	14	in	in	ADP
fnp-3317	36	15	the	the	DET
fnp-3317	36	16	distribution	distribution	NOUN
fnp-3317	36	17	of	of	ADP
fnp-3317	36	18	the	the	DET
fnp-3317	36	19	middle	middle	ADJ
fnp-3317	36	20	cerebral	cerebral	ADJ
fnp-3317	36	21	artery	artery	NOUN
fnp-3317	36	22	territory	territory	NOUN
fnp-3317	36	23	.	.	PUNCT
fnp-3317	37	1	c.	c.	PROPN
fnp-3317	37	2	luxol	luxol	PROPN
fnp-3317	37	3	fast	fast	PROPN
fnp-3317	37	4	blue	blue	PROPN
fnp-3317	37	5	counterstained	counterstaine	VERB
fnp-3317	37	6	hematoxylin	hematoxylin	NOUN
fnp-3317	37	7	and	and	CCONJ
fnp-3317	37	8	eosin	eosin	NOUN
fnp-3317	37	9	(	(	PUNCT
fnp-3317	37	10	lh	lh	PROPN
fnp-3317	37	11	&	&	CCONJ
fnp-3317	37	12	e	e	NOUN
fnp-3317	37	13	)	)	PUNCT
fnp-3317	37	14	section	section	NOUN
fnp-3317	37	15	showing	show	VERB
fnp-3317	37	16	subacute	subacute	NOUN
fnp-3317	37	17	hemorrhagic	hemorrhagic	ADJ
fnp-3317	37	18	infarction	infarction	NOUN
fnp-3317	37	19	.	.	PUNCT
fnp-3317	38	1	d.	d.	PROPN
fnp-3317	38	2	lh	lh	PROPN
fnp-3317	38	3	&	&	CCONJ
fnp-3317	38	4	e	e	NOUN
fnp-3317	38	5	-	-	ADJ
fnp-3317	38	6	stained	stain	VERB
fnp-3317	38	7	section	section	NOUN
fnp-3317	38	8	from	from	ADP
fnp-3317	38	9	the	the	DET
fnp-3317	38	10	neocortical	neocortical	ADJ
fnp-3317	38	11	white	white	ADJ
fnp-3317	38	12	matter	matter	NOUN
fnp-3317	38	13	in	in	ADP
fnp-3317	38	14	a	a	DET
fnp-3317	38	15	29	29	NUM
fnp-3317	38	16	-	-	PUNCT
fnp-3317	38	17	year	year	NOUN
fnp-3317	38	18	-	-	PUNCT
fnp-3317	38	19	old	old	ADJ
fnp-3317	38	20	male	male	NOUN
fnp-3317	38	21	covid-19	covid-19	PROPN
fnp-3317	38	22	patient	patient	NOUN
fnp-3317	38	23	with	with	ADP
fnp-3317	38	24	acute	acute	NOUN
fnp-3317	38	25	disseminated	disseminate	VERB
fnp-3317	38	26	encephalomyelitis	encephalomyelitis	NOUN
fnp-3317	38	27	(	(	PUNCT
fnp-3317	38	28	adem	adem	PROPN
fnp-3317	38	29	)	)	PUNCT
fnp-3317	38	30	.	.	PUNCT
fnp-3317	39	1	neurologists	neurologist	NOUN
fnp-3317	39	2	and	and	CCONJ
fnp-3317	39	3	other	other	ADJ
fnp-3317	39	4	clinicians	clinician	NOUN
fnp-3317	39	5	have	have	AUX
fnp-3317	39	6	been	be	AUX
fnp-3317	39	7	describing	describe	VERB
fnp-3317	39	8	persistent	persistent	ADJ
fnp-3317	39	9	neurological	neurological	ADJ
fnp-3317	39	10	symptomatology	symptomatology	NOUN
fnp-3317	39	11	in	in	ADP
fnp-3317	39	12	covid-19	covid-19	PROPN
fnp-3317	39	13	survivors	survivor	NOUN
fnp-3317	39	14	,	,	PUNCT
fnp-3317	39	15	including	include	VERB
fnp-3317	39	16	inattentiveness	inattentiveness	NOUN
fnp-3317	39	17	,	,	PUNCT
fnp-3317	39	18	memory	memory	NOUN
fnp-3317	39	19	impairment	impairment	NOUN
fnp-3317	39	20	and	and	CCONJ
fnp-3317	39	21	a	a	DET
fnp-3317	39	22	constellation	constellation	NOUN
fnp-3317	39	23	of	of	ADP
fnp-3317	39	24	other	other	ADJ
fnp-3317	39	25	cognitive	cognitive	ADJ
fnp-3317	39	26	symptoms	symptom	NOUN
fnp-3317	39	27	(	(	PUNCT
fnp-3317	39	28	i.e.	i.e.	X
fnp-3317	39	29	,	,	PUNCT
fnp-3317	39	30	“	"	PUNCT
fnp-3317	39	31	brain	brain	NOUN
fnp-3317	39	32	fog	fog	NOUN
fnp-3317	39	33	”	"	PUNCT
fnp-3317	39	34	)	)	PUNCT
fnp-3317	39	35	.	.	PUNCT
fnp-3317	40	1	these	these	PRON
fnp-3317	40	2	are	be	AUX
fnp-3317	40	3	part	part	NOUN
fnp-3317	40	4	of	of	ADP
fnp-3317	40	5	an	an	DET
fnp-3317	40	6	entity	entity	NOUN
fnp-3317	40	7	now	now	ADV
fnp-3317	40	8	termed	term	VERB
fnp-3317	40	9	the	the	DET
fnp-3317	40	10	post	post	ADJ
fnp-3317	40	11	-	-	ADJ
fnp-3317	40	12	acute	acute	ADJ
fnp-3317	40	13	covid-19	covid-19	PROPN
fnp-3317	40	14	syndrome	syndrome	NOUN
fnp-3317	40	15	(	(	PUNCT
fnp-3317	40	16	pacs	pac	NOUN
fnp-3317	40	17	)	)	PUNCT
fnp-3317	40	18	.	.	PUNCT
fnp-3317	41	1	the	the	DET
fnp-3317	41	2	underlying	underlie	VERB
fnp-3317	41	3	neuropathological	neuropathological	ADJ
fnp-3317	41	4	substrate	substrate	NOUN
fnp-3317	41	5	for	for	ADP
fnp-3317	41	6	these	these	DET
fnp-3317	41	7	findings	finding	NOUN
fnp-3317	41	8	remains	remain	VERB
fnp-3317	41	9	unclear	unclear	ADJ
fnp-3317	41	10	,	,	PUNCT
fnp-3317	41	11	but	but	CCONJ
fnp-3317	41	12	the	the	DET
fnp-3317	41	13	effects	effect	NOUN
fnp-3317	41	14	of	of	ADP
fnp-3317	41	15	hypoxic	hypoxic	ADJ
fnp-3317	41	16	-	-	PUNCT
fnp-3317	41	17	ischemic	ischemic	ADJ
fnp-3317	41	18	injury	injury	NOUN
fnp-3317	41	19	,	,	PUNCT
fnp-3317	41	20	chronic	chronic	ADJ
fnp-3317	41	21	neuroinflammation	neuroinflammation	NOUN
fnp-3317	41	22	,	,	PUNCT
fnp-3317	41	23	toxic	toxic	ADJ
fnp-3317	41	24	encephalopathy	encephalopathy	ADV
fnp-3317	41	25	from	from	ADP
fnp-3317	41	26	breakdown	breakdown	NOUN
fnp-3317	41	27	of	of	ADP
fnp-3317	41	28	the	the	DET
fnp-3317	41	29	blood	blood	NOUN
fnp-3317	41	30	brain	brain	NOUN
fnp-3317	41	31	barrier	barrier	NOUN
fnp-3317	41	32	are	be	AUX
fnp-3317	41	33	candidates	candidate	NOUN
fnp-3317	41	34	.	.	PUNCT
fnp-3317	42	1	direct	direct	ADJ
fnp-3317	42	2	effects	effect	NOUN
fnp-3317	42	3	of	of	ADP
fnp-3317	42	4	the	the	DET
fnp-3317	42	5	virus	virus	NOUN
fnp-3317	42	6	are	be	AUX
fnp-3317	42	7	not	not	PART
fnp-3317	42	8	completely	completely	ADV
fnp-3317	42	9	ruled	rule	VERB
fnp-3317	42	10	out	out	ADP
fnp-3317	42	11	,	,	PUNCT
fnp-3317	42	12	and	and	CCONJ
fnp-3317	42	13	the	the	DET
fnp-3317	42	14	potential	potential	NOUN
fnp-3317	42	15	for	for	ADP
fnp-3317	42	16	neurotropic	neurotropic	ADJ
fnp-3317	42	17	strains	strain	NOUN
fnp-3317	42	18	to	to	PART
fnp-3317	42	19	emerge	emerge	VERB
fnp-3317	42	20	remains	remain	VERB
fnp-3317	42	21	a	a	DET
fnp-3317	42	22	possibility	possibility	NOUN
fnp-3317	42	23	.	.	PUNCT
fnp-3317	43	1	given	give	VERB
fnp-3317	43	2	the	the	DET
fnp-3317	43	3	existence	existence	NOUN
fnp-3317	43	4	of	of	ADP
fnp-3317	43	5	encephalitis	encephalitis	ADJ
fnp-3317	43	6	lethargica	lethargica	NOUN
fnp-3317	43	7	and	and	CCONJ
fnp-3317	43	8	measles	measle	NOUN
fnp-3317	43	9	related	relate	VERB
fnp-3317	43	10	subacute	subacute	VERB
fnp-3317	43	11	sclerosing	sclerose	VERB
fnp-3317	43	12	panencephalitis	panencephalitis	NOUN
fnp-3317	43	13	,	,	PUNCT
fnp-3317	43	14	both	both	DET
fnp-3317	43	15	virus	virus	NOUN
fnp-3317	43	16	related	relate	VERB
fnp-3317	43	17	and	and	CCONJ
fnp-3317	43	18	associated	associate	VERB
fnp-3317	43	19	with	with	ADP
fnp-3317	43	20	neurofibrillary	neurofibrillary	ADJ
fnp-3317	43	21	tangles	tangle	NOUN
fnp-3317	43	22	,	,	PUNCT
fnp-3317	43	23	it	it	PRON
fnp-3317	43	24	is	be	AUX
fnp-3317	43	25	not	not	PART
fnp-3317	43	26	unreasonable	unreasonable	ADJ
fnp-3317	43	27	to	to	PART
fnp-3317	43	28	speculate	speculate	VERB
fnp-3317	43	29	that	that	SCONJ
fnp-3317	43	30	a	a	DET
fnp-3317	43	31	degenerative	degenerative	ADJ
fnp-3317	43	32	component	component	NOUN
fnp-3317	43	33	of	of	ADP
fnp-3317	43	34	pacs	pac	NOUN
fnp-3317	43	35	might	might	AUX
fnp-3317	43	36	exist	exist	VERB
fnp-3317	43	37	.	.	PUNCT
fnp-3317	44	1	critically	critically	ADV
fnp-3317	44	2	,	,	PUNCT
fnp-3317	44	3	it	it	PRON
fnp-3317	44	4	is	be	AUX
fnp-3317	44	5	imperative	imperative	ADJ
fnp-3317	44	6	to	to	PART
fnp-3317	44	7	understand	understand	VERB
fnp-3317	44	8	whether	whether	SCONJ
fnp-3317	44	9	these	these	DET
fnp-3317	44	10	pacs	pac	NOUN
fnp-3317	44	11	neurological	neurological	ADJ
fnp-3317	44	12	symptoms	symptom	NOUN
fnp-3317	44	13	are	be	AUX
fnp-3317	44	14	progressive	progressive	ADJ
fnp-3317	44	15	and	and	CCONJ
fnp-3317	44	16	we	we	PRON
fnp-3317	44	17	expect	expect	VERB
fnp-3317	44	18	a	a	DET
fnp-3317	44	19	surge	surge	NOUN
fnp-3317	44	20	in	in	ADP
fnp-3317	44	21	translational	translational	ADJ
fnp-3317	44	22	studies	study	NOUN
fnp-3317	44	23	in	in	ADP
fnp-3317	44	24	the	the	DET
fnp-3317	44	25	coming	come	VERB
fnp-3317	44	26	years	year	NOUN
fnp-3317	44	27	focused	focus	VERB
fnp-3317	44	28	on	on	ADP
fnp-3317	44	29	the	the	DET
fnp-3317	44	30	long	long	ADJ
fnp-3317	44	31	-	-	PUNCT
fnp-3317	44	32	term	term	NOUN
fnp-3317	44	33	changes	change	NOUN
fnp-3317	44	34	that	that	PRON
fnp-3317	44	35	follow	follow	VERB
fnp-3317	44	36	covid-19	covid-19	PROPN
fnp-3317	44	37	.	.	PUNCT
fnp-3317	44	38	  	  	SPACE
fnp-3317	44	39	2	2	X
fnp-3317	44	40	.	.	PUNCT
fnp-3317	45	1	proteomic	proteomic	ADJ
fnp-3317	45	2	analysis	analysis	NOUN
fnp-3317	45	3	:	:	PUNCT
fnp-3317	45	4	spotlight	spotlight	NOUN
fnp-3317	45	5	on	on	ADP
fnp-3317	45	6	microglial	microglial	ADJ
fnp-3317	45	7	and	and	CCONJ
fnp-3317	45	8	astrocyte	astrocyte	NOUN
fnp-3317	45	9	inflammation	inflammation	NOUN
fnp-3317	45	10	in	in	ADP
fnp-3317	45	11	alzheimer	alzheimer	PROPN
fnp-3317	45	12	disease	disease	NOUN
fnp-3317	45	13	in	in	ADP
fnp-3317	45	14	the	the	DET
fnp-3317	45	15	previous	previous	ADJ
fnp-3317	45	16	decades	decade	NOUN
fnp-3317	45	17	,	,	PUNCT
fnp-3317	45	18	transformative	transformative	ADJ
fnp-3317	45	19	technologies	technology	NOUN
fnp-3317	45	20	have	have	AUX
fnp-3317	45	21	enabled	enable	VERB
fnp-3317	45	22	large	large	ADJ
fnp-3317	45	23	-	-	PUNCT
fnp-3317	45	24	scale	scale	NOUN
fnp-3317	45	25	genomic	genomic	NOUN
fnp-3317	45	26	and	and	CCONJ
fnp-3317	45	27	transcriptomic	transcriptomic	ADJ
fnp-3317	45	28	studies	study	NOUN
fnp-3317	45	29	of	of	ADP
fnp-3317	45	30	post	post	ADJ
fnp-3317	45	31	-	-	ADJ
fnp-3317	45	32	mortem	mortem	ADJ
fnp-3317	45	33	brain	brain	NOUN
fnp-3317	45	34	tissues	tissue	NOUN
fnp-3317	45	35	that	that	PRON
fnp-3317	45	36	have	have	AUX
fnp-3317	45	37	been	be	AUX
fnp-3317	45	38	directed	direct	VERB
fnp-3317	45	39	towards	towards	ADP
fnp-3317	45	40	neurodegenerative	neurodegenerative	ADJ
fnp-3317	45	41	diseases	disease	NOUN
fnp-3317	45	42	,	,	PUNCT
fnp-3317	45	43	yielding	yield	VERB
fnp-3317	45	44	a	a	DET
fnp-3317	45	45	flood	flood	NOUN
fnp-3317	45	46	of	of	ADP
fnp-3317	45	47	data	datum	NOUN
fnp-3317	45	48	out	out	ADP
fnp-3317	45	49	of	of	ADP
fnp-3317	45	50	which	which	PRON
fnp-3317	45	51	has	have	AUX
fnp-3317	45	52	emerged	emerge	VERB
fnp-3317	45	53	a	a	DET
fnp-3317	45	54	rich	rich	ADJ
fnp-3317	45	55	and	and	CCONJ
fnp-3317	45	56	complex	complex	ADJ
fnp-3317	45	57	picture	picture	NOUN
fnp-3317	45	58	of	of	ADP
fnp-3317	45	59	alzheimer	alzheimer	PROPN
fnp-3317	45	60	disease	disease	NOUN
fnp-3317	45	61	(	(	PUNCT
fnp-3317	45	62	ad	ad	NOUN
fnp-3317	45	63	)	)	PUNCT
fnp-3317	45	64	.	.	PUNCT
fnp-3317	46	1	but	but	CCONJ
fnp-3317	46	2	what	what	PRON
fnp-3317	46	3	about	about	ADP
fnp-3317	46	4	the	the	DET
fnp-3317	46	5	proteins	protein	NOUN
fnp-3317	46	6	?	?	PUNCT
fnp-3317	47	1	owning	own	VERB
fnp-3317	47	2	to	to	ADP
fnp-3317	47	3	their	their	PRON
fnp-3317	47	4	relatively	relatively	ADV
fnp-3317	47	5	more	more	ADV
fnp-3317	47	6	complex	complex	ADJ
fnp-3317	47	7	chemical	chemical	NOUN
fnp-3317	47	8	structures	structure	NOUN
fnp-3317	47	9	,	,	PUNCT
fnp-3317	47	10	measuring	measure	VERB
fnp-3317	47	11	structural	structural	ADJ
fnp-3317	47	12	changes	change	NOUN
fnp-3317	47	13	on	on	ADP
fnp-3317	47	14	the	the	DET
fnp-3317	47	15	protein	protein	NOUN
fnp-3317	47	16	level	level	NOUN
fnp-3317	47	17	in	in	ADP
fnp-3317	47	18	a	a	DET
fnp-3317	47	19	high	high	ADJ
fnp-3317	47	20	throughput	throughput	NOUN
fnp-3317	47	21	manner	manner	NOUN
fnp-3317	47	22	is	be	AUX
fnp-3317	47	23	much	much	ADV
fnp-3317	47	24	more	more	ADV
fnp-3317	47	25	challenging	challenging	ADJ
fnp-3317	47	26	.	.	PUNCT
fnp-3317	48	1	but	but	CCONJ
fnp-3317	48	2	now	now	ADV
fnp-3317	48	3	,	,	PUNCT
fnp-3317	48	4	proteomic	proteomic	ADJ
fnp-3317	48	5	technologies	technology	NOUN
fnp-3317	48	6	have	have	AUX
fnp-3317	48	7	advanced	advance	VERB
fnp-3317	48	8	sufficiently	sufficiently	ADV
fnp-3317	48	9	,	,	PUNCT
fnp-3317	48	10	and	and	CCONJ
fnp-3317	48	11	we	we	PRON
fnp-3317	48	12	are	be	AUX
fnp-3317	48	13	beginning	begin	VERB
fnp-3317	48	14	to	to	PART
fnp-3317	48	15	see	see	VERB
fnp-3317	48	16	them	they	PRON
fnp-3317	48	17	take	take	VERB
fnp-3317	48	18	center	center	NOUN
fnp-3317	48	19	stage	stage	NOUN
fnp-3317	48	20	.	.	PUNCT
fnp-3317	49	1	here	here	ADV
fnp-3317	49	2	and	and	CCONJ
fnp-3317	49	3	in	in	ADP
fnp-3317	49	4	the	the	DET
fnp-3317	49	5	next	next	ADJ
fnp-3317	49	6	two	two	NUM
fnp-3317	49	7	sections	section	NOUN
fnp-3317	49	8	we	we	PRON
fnp-3317	49	9	highlight	highlight	VERB
fnp-3317	49	10	three	three	NUM
fnp-3317	49	11	such	such	ADJ
fnp-3317	49	12	studies	study	NOUN
fnp-3317	49	13	.	.	PUNCT
fnp-3317	50	1	the	the	DET
fnp-3317	50	2	first	first	ADJ
fnp-3317	50	3	study	study	NOUN
fnp-3317	50	4	,	,	PUNCT
fnp-3317	50	5	published	publish	VERB
fnp-3317	50	6	in	in	ADP
fnp-3317	50	7	nature	nature	NOUN
fnp-3317	50	8	medicine	medicine	NOUN
fnp-3317	50	9	,	,	PUNCT
fnp-3317	50	10	led	lead	VERB
fnp-3317	50	11	by	by	ADP
fnp-3317	50	12	nicholas	nicholas	PROPN
fnp-3317	50	13	seyfried	seyfried	PROPN
fnp-3317	50	14	and	and	CCONJ
fnp-3317	50	15	allan	allan	PROPN
fnp-3317	50	16	levey	levey	PROPN
fnp-3317	50	17	at	at	ADP
fnp-3317	50	18	emory	emory	PROPN
fnp-3317	50	19	university	university	PROPN
fnp-3317	50	20	,	,	PUNCT
fnp-3317	50	21	profiled	profile	VERB
fnp-3317	50	22	2,000	2,000	NUM
fnp-3317	50	23	brain	brain	NOUN
fnp-3317	50	24	samples	sample	NOUN
fnp-3317	50	25	,	,	PUNCT
fnp-3317	50	26	comparing	compare	VERB
fnp-3317	50	27	more	more	ADJ
fnp-3317	50	28	than	than	ADP
fnp-3317	50	29	3,000	3,000	NUM
fnp-3317	50	30	proteins	protein	NOUN
fnp-3317	50	31	from	from	ADP
fnp-3317	50	32	multiple	multiple	ADJ
fnp-3317	50	33	cohorts	cohort	NOUN
fnp-3317	50	34	,	,	PUNCT
fnp-3317	50	35	including	include	VERB
fnp-3317	50	36	controls	control	NOUN
fnp-3317	50	37	,	,	PUNCT
fnp-3317	50	38	people	people	NOUN
fnp-3317	50	39	with	with	ADP
fnp-3317	50	40	asymptomatic	asymptomatic	ADJ
fnp-3317	50	41	ad	ad	NOUN
fnp-3317	50	42	neuropathology	neuropathology	NOUN
fnp-3317	50	43	and	and	CCONJ
fnp-3317	50	44	those	those	PRON
fnp-3317	50	45	with	with	ADP
fnp-3317	50	46	dementia	dementia	NOUN
fnp-3317	50	47	due	due	ADP
fnp-3317	50	48	to	to	ADP
fnp-3317	50	49	ad	ad	NOUN
fnp-3317	50	50	(	(	PUNCT
fnp-3317	50	51	johnson	johnson	PROPN
fnp-3317	50	52	et	et	PROPN
fnp-3317	50	53	al	al	PROPN
fnp-3317	50	54	.	.	PROPN
fnp-3317	50	55	,	,	PUNCT
fnp-3317	50	56	2020	2020	NUM
fnp-3317	50	57	)	)	PUNCT
fnp-3317	50	58	.	.	PUNCT
fnp-3317	51	1	cases	case	NOUN
fnp-3317	51	2	were	be	AUX
fnp-3317	51	3	derived	derive	VERB
fnp-3317	51	4	from	from	ADP
fnp-3317	51	5	a	a	DET
fnp-3317	51	6	total	total	NOUN
fnp-3317	51	7	of	of	ADP
fnp-3317	51	8	eight	eight	NUM
fnp-3317	51	9	collections	collection	NOUN
fnp-3317	51	10	,	,	PUNCT
fnp-3317	51	11	including	include	VERB
fnp-3317	51	12	the	the	DET
fnp-3317	51	13	religious	religious	ADJ
fnp-3317	51	14	orders	order	NOUN
fnp-3317	51	15	study	study	VERB
fnp-3317	51	16	and	and	CCONJ
fnp-3317	51	17	memory	memory	NOUN
fnp-3317	51	18	and	and	CCONJ
fnp-3317	51	19	aging	age	VERB
fnp-3317	51	20	project	project	NOUN
fnp-3317	51	21	(	(	PUNCT
fnp-3317	51	22	ros	ros	PROPN
fnp-3317	51	23	-	-	PUNCT
fnp-3317	51	24	map	map	NOUN
fnp-3317	51	25	)	)	PUNCT
fnp-3317	51	26	,	,	PUNCT
fnp-3317	51	27	mayo	mayo	NOUN
fnp-3317	51	28	clinic	clinic	PROPN
fnp-3317	51	29	brain	brain	PROPN
fnp-3317	51	30	bank	bank	PROPN
fnp-3317	51	31	,	,	PUNCT
fnp-3317	51	32	baltimore	baltimore	PROPN
fnp-3317	51	33	longitudinal	longitudinal	ADJ
fnp-3317	51	34	study	study	NOUN
fnp-3317	51	35	of	of	ADP
fnp-3317	51	36	aging	age	VERB
fnp-3317	51	37	(	(	PUNCT
fnp-3317	51	38	blsa	blsa	NOUN
fnp-3317	51	39	)	)	PUNCT
fnp-3317	51	40	,	,	PUNCT
fnp-3317	51	41	baltimore	baltimore	PROPN
fnp-3317	51	42	coroner	coroner	PROPN
fnp-3317	51	43	’s	’s	PART
fnp-3317	51	44	office	office	NOUN
fnp-3317	51	45	,	,	PUNCT
fnp-3317	51	46	banner	banner	NOUN
fnp-3317	51	47	sun	sun	PROPN
fnp-3317	51	48	health	health	PROPN
fnp-3317	51	49	research	research	PROPN
fnp-3317	51	50	institute	institute	PROPN
fnp-3317	51	51	,	,	PUNCT
fnp-3317	51	52	mount	mount	PROPN
fnp-3317	51	53	sinai	sinai	PROPN
fnp-3317	51	54	school	school	PROPN
fnp-3317	51	55	of	of	ADP
fnp-3317	51	56	medicine	medicine	NOUN
fnp-3317	51	57	brain	brain	PROPN
fnp-3317	51	58	bank	bank	PROPN
fnp-3317	51	59	,	,	PUNCT
fnp-3317	51	60	adult	adult	NOUN
fnp-3317	51	61	changes	change	NOUN
fnp-3317	51	62	in	in	ADP
fnp-3317	51	63	thought	thought	NOUN
fnp-3317	51	64	study	study	NOUN
fnp-3317	51	65	(	(	PUNCT
fnp-3317	51	66	act	act	PROPN
fnp-3317	51	67	)	)	PUNCT
fnp-3317	51	68	,	,	PUNCT
fnp-3317	51	69	and	and	CCONJ
fnp-3317	51	70	university	university	PROPN
fnp-3317	51	71	of	of	ADP
fnp-3317	51	72	pennsylvania	pennsylvania	PROPN
fnp-3317	51	73	school	school	PROPN
fnp-3317	51	74	of	of	ADP
fnp-3317	51	75	medicine	medicine	PROPN
fnp-3317	51	76	brain	brain	NOUN
fnp-3317	51	77	bank	bank	PROPN
fnp-3317	51	78	.	.	PUNCT
fnp-3317	52	1	researchers	researcher	NOUN
fnp-3317	52	2	identified	identify	VERB
fnp-3317	52	3	13	13	NUM
fnp-3317	52	4	different	different	ADJ
fnp-3317	52	5	gene	gene	NOUN
fnp-3317	52	6	sets	set	NOUN
fnp-3317	52	7	(	(	PUNCT
fnp-3317	52	8	“	"	PUNCT
fnp-3317	52	9	modules	module	NOUN
fnp-3317	52	10	”	"	PUNCT
fnp-3317	52	11	)	)	PUNCT
fnp-3317	52	12	based	base	VERB
fnp-3317	52	13	on	on	ADP
fnp-3317	52	14	co	co	ADJ
fnp-3317	52	15	-	-	NOUN
fnp-3317	52	16	expression	expression	ADJ
fnp-3317	52	17	patterns	pattern	NOUN
fnp-3317	52	18	(	(	PUNCT
fnp-3317	52	19	figure	figure	NOUN
fnp-3317	52	20	2	2	NUM
fnp-3317	52	21	)	)	PUNCT
fnp-3317	52	22	.	.	PUNCT
fnp-3317	53	1	of	of	ADP
fnp-3317	53	2	these	these	PRON
fnp-3317	53	3	,	,	PUNCT
fnp-3317	53	4	six	six	NUM
fnp-3317	53	5	were	be	AUX
fnp-3317	53	6	correlated	correlate	VERB
fnp-3317	53	7	with	with	ADP
fnp-3317	53	8	ad	ad	NOUN
fnp-3317	53	9	neuropathological	neuropathological	ADJ
fnp-3317	53	10	features	feature	NOUN
fnp-3317	53	11	(	(	PUNCT
fnp-3317	53	12	i.e.	i.e.	X
fnp-3317	53	13	,	,	PUNCT
fnp-3317	53	14	amyloid	amyloid	NOUN
fnp-3317	53	15	plaques	plaque	NOUN
fnp-3317	53	16	,	,	PUNCT
fnp-3317	53	17	neurofibrillary	neurofibrillary	ADJ
fnp-3317	53	18	tangles	tangle	NOUN
fnp-3317	53	19	)	)	PUNCT
fnp-3317	53	20	or	or	CCONJ
fnp-3317	53	21	cognitive	cognitive	ADJ
fnp-3317	53	22	impairment	impairment	NOUN
fnp-3317	53	23	.	.	PUNCT
fnp-3317	54	1	of	of	ADP
fnp-3317	54	2	the	the	DET
fnp-3317	54	3	three	three	NUM
fnp-3317	54	4	that	that	PRON
fnp-3317	54	5	were	be	AUX
fnp-3317	54	6	most	most	ADV
fnp-3317	54	7	closely	closely	ADV
fnp-3317	54	8	correlated	correlate	VERB
fnp-3317	54	9	with	with	ADP
fnp-3317	54	10	ad	ad	NOUN
fnp-3317	54	11	features	feature	NOUN
fnp-3317	54	12	,	,	PUNCT
fnp-3317	54	13	two	two	NUM
fnp-3317	54	14	were	be	AUX
fnp-3317	54	15	downregulated	downregulate	VERB
fnp-3317	54	16	,	,	PUNCT
fnp-3317	54	17	including	include	VERB
fnp-3317	54	18	the	the	DET
fnp-3317	54	19	m1	m1	NOUN
fnp-3317	54	20	that	that	PRON
fnp-3317	54	21	was	be	AUX
fnp-3317	54	22	composed	compose	VERB
fnp-3317	54	23	of	of	ADP
fnp-3317	54	24	proteins	protein	NOUN
fnp-3317	54	25	involved	involve	VERB
fnp-3317	54	26	in	in	ADP
fnp-3317	54	27	synaptic	synaptic	ADJ
fnp-3317	54	28	function	function	NOUN
fnp-3317	54	29	and	and	CCONJ
fnp-3317	54	30	the	the	DET
fnp-3317	54	31	m3	m3	PROPN
fnp-3317	54	32	that	that	PRON
fnp-3317	54	33	tracked	track	VERB
fnp-3317	54	34	with	with	ADP
fnp-3317	54	35	mitochondrial	mitochondrial	ADJ
fnp-3317	54	36	proteins	protein	NOUN
fnp-3317	54	37	.	.	PUNCT
fnp-3317	55	1	m4	m4	PROPN
fnp-3317	55	2	had	have	VERB
fnp-3317	55	3	the	the	DET
fnp-3317	55	4	strongest	strong	ADJ
fnp-3317	55	5	correlation	correlation	NOUN
fnp-3317	55	6	with	with	ADP
fnp-3317	55	7	disease	disease	NOUN
fnp-3317	55	8	traits	trait	NOUN
fnp-3317	55	9	and	and	CCONJ
fnp-3317	55	10	contained	contain	VERB
fnp-3317	55	11	astrocyte	astrocyte	NOUN
fnp-3317	55	12	and	and	CCONJ
fnp-3317	55	13	microglial	microglial	ADJ
fnp-3317	55	14	proteins	protein	NOUN
fnp-3317	55	15	involved	involve	VERB
fnp-3317	55	16	in	in	ADP
fnp-3317	55	17	sugar	sugar	NOUN
fnp-3317	55	18	metabolism	metabolism	NOUN
fnp-3317	55	19	.	.	PUNCT
fnp-3317	56	1	intriguingly	intriguingly	ADV
fnp-3317	56	2	,	,	PUNCT
fnp-3317	56	3	many	many	ADJ
fnp-3317	56	4	of	of	ADP
fnp-3317	56	5	the	the	DET
fnp-3317	56	6	proteins	protein	NOUN
fnp-3317	56	7	in	in	ADP
fnp-3317	56	8	the	the	DET
fnp-3317	56	9	m4	m4	PROPN
fnp-3317	56	10	module	module	NOUN
fnp-3317	56	11	were	be	AUX
fnp-3317	56	12	encoded	encode	VERB
fnp-3317	56	13	by	by	ADP
fnp-3317	56	14	genes	gene	NOUN
fnp-3317	56	15	that	that	PRON
fnp-3317	56	16	are	be	AUX
fnp-3317	56	17	ad	ad	NOUN
fnp-3317	56	18	risk	risk	NOUN
fnp-3317	56	19	loci	locus	NOUN
fnp-3317	56	20	.	.	PUNCT
fnp-3317	57	1	importantly	importantly	ADV
fnp-3317	57	2	,	,	PUNCT
fnp-3317	57	3	regardless	regardless	ADV
fnp-3317	57	4	of	of	ADP
fnp-3317	57	5	their	their	PRON
fnp-3317	57	6	precise	precise	ADJ
fnp-3317	57	7	function	function	NOUN
fnp-3317	57	8	and	and	CCONJ
fnp-3317	57	9	role	role	NOUN
fnp-3317	57	10	in	in	ADP
fnp-3317	57	11	disease	disease	NOUN
fnp-3317	57	12	,	,	PUNCT
fnp-3317	57	13	27	27	NUM
fnp-3317	57	14	of	of	ADP
fnp-3317	57	15	them	they	PRON
fnp-3317	57	16	were	be	AUX
fnp-3317	57	17	detected	detect	VERB
fnp-3317	57	18	in	in	ADP
fnp-3317	57	19	csf	csf	NOUN
fnp-3317	57	20	,	,	PUNCT
fnp-3317	57	21	underscoring	underscore	VERB
fnp-3317	57	22	their	their	PRON
fnp-3317	57	23	potential	potential	ADJ
fnp-3317	57	24	utility	utility	NOUN
fnp-3317	57	25	as	as	ADP
fnp-3317	57	26	biomarkers	biomarker	NOUN
fnp-3317	57	27	.	.	PUNCT
fnp-3317	58	1	because	because	SCONJ
fnp-3317	58	2	this	this	PRON
fnp-3317	58	3	was	be	AUX
fnp-3317	58	4	funded	fund	VERB
fnp-3317	58	5	by	by	ADP
fnp-3317	58	6	the	the	DET
fnp-3317	58	7	accelerating	accelerate	VERB
fnp-3317	58	8	medicine	medicine	NOUN
fnp-3317	58	9	partnership	partnership	NOUN
fnp-3317	58	10	ad	ad	NOUN
fnp-3317	58	11	(	(	PUNCT
fnp-3317	58	12	amp	amp	NOUN
fnp-3317	58	13	-	-	PUNCT
fnp-3317	58	14	ad	ad	NOUN
fnp-3317	58	15	)	)	PUNCT
fnp-3317	58	16	project	project	NOUN
fnp-3317	58	17	,	,	PUNCT
fnp-3317	58	18	all	all	PRON
fnp-3317	58	19	of	of	ADP
fnp-3317	58	20	these	these	DET
fnp-3317	58	21	data	datum	NOUN
fnp-3317	58	22	are	be	AUX
fnp-3317	58	23	publicly	publicly	ADV
fnp-3317	58	24	available	available	ADJ
fnp-3317	58	25	for	for	ADP
fnp-3317	58	26	the	the	DET
fnp-3317	58	27	research	research	NOUN
fnp-3317	58	28	community	community	NOUN
fnp-3317	58	29	and	and	CCONJ
fnp-3317	58	30	will	will	AUX
fnp-3317	58	31	surely	surely	ADV
fnp-3317	58	32	catalyze	catalyze	VERB
fnp-3317	58	33	continued	continue	VERB
fnp-3317	58	34	proteomic	proteomic	ADJ
fnp-3317	58	35	studies	study	NOUN
fnp-3317	58	36	.	.	PUNCT
fnp-3317	59	1	figure	figure	NOUN
fnp-3317	59	2	2	2	NUM
fnp-3317	59	3	.	.	PUNCT
fnp-3317	59	4	protein	protein	NOUN
fnp-3317	59	5	network	network	NOUN
fnp-3317	59	6	analysis	analysis	NOUN
fnp-3317	59	7	in	in	ADP
fnp-3317	59	8	post	post	ADJ
fnp-3317	59	9	-	-	ADJ
fnp-3317	59	10	mortem	mortem	ADJ
fnp-3317	59	11	alzheimer	alzheimer	NOUN
fnp-3317	59	12	disease	disease	NOUN
fnp-3317	59	13	(	(	PUNCT
fnp-3317	59	14	ad	ad	NOUN
fnp-3317	59	15	)	)	PUNCT
fnp-3317	59	16	brain	brain	NOUN
fnp-3317	59	17	.	.	PUNCT
fnp-3317	60	1	a.	a.	NOUN
fnp-3317	60	2	brain	brain	NOUN
fnp-3317	60	3	tissue	tissue	NOUN
fnp-3317	60	4	from	from	ADP
fnp-3317	60	5	the	the	DET
fnp-3317	60	6	dorsolateral	dorsolateral	ADJ
fnp-3317	60	7	prefrontal	prefrontal	ADJ
fnp-3317	60	8	cortex	cortex	NOUN
fnp-3317	60	9	from	from	ADP
fnp-3317	60	10	ad	ad	NOUN
fnp-3317	60	11	patients	patient	NOUN
fnp-3317	60	12	and	and	CCONJ
fnp-3317	60	13	compared	compare	VERB
fnp-3317	60	14	to	to	ADP
fnp-3317	60	15	cognitively	cognitively	ADV
fnp-3317	60	16	normal	normal	ADJ
fnp-3317	60	17	subjects	subject	NOUN
fnp-3317	60	18	with	with	ADP
fnp-3317	60	19	age	age	NOUN
fnp-3317	60	20	-	-	PUNCT
fnp-3317	60	21	related	relate	VERB
fnp-3317	60	22	pathology	pathology	NOUN
fnp-3317	60	23	and	and	CCONJ
fnp-3317	60	24	pathologically	pathologically	ADV
fnp-3317	60	25	negative	negative	ADJ
fnp-3317	60	26	controls	control	NOUN
fnp-3317	60	27	from	from	ADP
fnp-3317	60	28	four	four	NUM
fnp-3317	60	29	cohorts	cohort	NOUN
fnp-3317	60	30	.	.	PUNCT
fnp-3317	61	1	b.	b.	PROPN
fnp-3317	62	1	a	a	DET
fnp-3317	62	2	correlation	correlation	NOUN
fnp-3317	62	3	network	network	NOUN
fnp-3317	62	4	consisting	consist	VERB
fnp-3317	62	5	of	of	ADP
fnp-3317	62	6	13	13	NUM
fnp-3317	62	7	modules	module	NOUN
fnp-3317	62	8	using	use	VERB
fnp-3317	62	9	3334	3334	NUM
fnp-3317	62	10	proteins	protein	NOUN
fnp-3317	62	11	was	be	AUX
fnp-3317	62	12	created	create	VERB
fnp-3317	62	13	and	and	CCONJ
fnp-3317	62	14	correlated	correlate	VERB
fnp-3317	62	15	with	with	ADP
fnp-3317	62	16	neuropathological	neuropathological	ADJ
fnp-3317	62	17	assessments	assessment	NOUN
fnp-3317	62	18	,	,	PUNCT
fnp-3317	62	19	cell	cell	NOUN
fnp-3317	62	20	type	type	NOUN
fnp-3317	62	21	markers	marker	NOUN
fnp-3317	62	22	,	,	PUNCT
fnp-3317	62	23	and	and	CCONJ
fnp-3317	62	24	the	the	DET
fnp-3317	62	25	associated	associated	ADJ
fnp-3317	62	26	biological	biological	ADJ
fnp-3317	62	27	processes	process	NOUN
fnp-3317	62	28	identified	identify	VERB
fnp-3317	62	29	using	use	VERB
fnp-3317	62	30	gene	gene	NOUN
fnp-3317	62	31	ontology	ontology	NOUN
fnp-3317	62	32	(	(	PUNCT
fnp-3317	62	33	go	go	VERB
fnp-3317	62	34	)	)	PUNCT
fnp-3317	62	35	analysis	analysis	NOUN
fnp-3317	62	36	.	.	PUNCT
fnp-3317	63	1	images	image	NOUN
fnp-3317	63	2	courtesy	courtesy	NOUN
fnp-3317	63	3	of	of	ADP
fnp-3317	63	4	dr	dr	PROPN
fnp-3317	63	5	.	.	PROPN
fnp-3317	63	6	erik	erik	PROPN
fnp-3317	63	7	c.	c.	PROPN
fnp-3317	63	8	johnson	johnson	PROPN
fnp-3317	63	9	,	,	PUNCT
fnp-3317	63	10	allan	allan	PROPN
fnp-3317	63	11	i.	i.	PROPN
fnp-3317	63	12	levy	levy	PROPN
fnp-3317	63	13	,	,	PUNCT
fnp-3317	63	14	nicholas	nicholas	PROPN
fnp-3317	63	15	t.	t.	PROPN
fnp-3317	63	16	seyfried	seyfried	PROPN
fnp-3317	63	17	,	,	PUNCT
fnp-3317	63	18	reproduced	reproduce	VERB
fnp-3317	63	19	with	with	ADP
fnp-3317	63	20	permission	permission	NOUN
fnp-3317	63	21	under	under	ADP
fnp-3317	63	22	the	the	DET
fnp-3317	63	23	creative	creative	ADJ
fnp-3317	63	24	commons	common	NOUN
fnp-3317	63	25	license	license	NOUN
fnp-3317	63	26	.	.	PUNCT
fnp-3317	64	1	3	3	X
fnp-3317	64	2	.	.	X
fnp-3317	64	3	proteomic	proteomic	ADJ
fnp-3317	64	4	analysis	analysis	NOUN
fnp-3317	64	5	:	:	PUNCT
fnp-3317	64	6	the	the	DET
fnp-3317	64	7	contribution	contribution	NOUN
fnp-3317	64	8	of	of	ADP
fnp-3317	64	9	cerebral	cerebral	ADJ
fnp-3317	64	10	atherosclerosis	atherosclerosis	NOUN
fnp-3317	64	11	to	to	PART
fnp-3317	64	12	cognitive	cognitive	ADJ
fnp-3317	64	13	decline	decline	NOUN
fnp-3317	64	14	another	another	DET
fnp-3317	64	15	proteomics	proteomic	NOUN
fnp-3317	64	16	paper	paper	NOUN
fnp-3317	64	17	published	publish	VERB
fnp-3317	64	18	in	in	ADP
fnp-3317	64	19	nature	nature	NOUN
fnp-3317	64	20	neuroscience	neuroscience	NOUN
fnp-3317	64	21	,	,	PUNCT
fnp-3317	64	22	also	also	ADV
fnp-3317	64	23	from	from	ADP
fnp-3317	64	24	emory	emory	PROPN
fnp-3317	64	25	university	university	PROPN
fnp-3317	64	26	led	lead	VERB
fnp-3317	64	27	by	by	ADP
fnp-3317	64	28	nicholas	nicholas	PROPN
fnp-3317	64	29	seyfried	seyfried	PROPN
fnp-3317	64	30	,	,	PUNCT
fnp-3317	64	31	allan	allan	PROPN
fnp-3317	64	32	levey	levey	PROPN
fnp-3317	64	33	,	,	PUNCT
fnp-3317	64	34	and	and	CCONJ
fnp-3317	64	35	thomas	thomas	PROPN
fnp-3317	64	36	s.	s.	PROPN
fnp-3317	64	37	wingo	wingo	PROPN
fnp-3317	64	38	,	,	PUNCT
fnp-3317	64	39	examined	examine	VERB
fnp-3317	64	40	cerebral	cerebral	ADJ
fnp-3317	64	41	atherosclerosis	atherosclerosis	NOUN
fnp-3317	64	42	as	as	SCONJ
fnp-3317	64	43	it	it	PRON
fnp-3317	64	44	relates	relate	VERB
fnp-3317	64	45	to	to	ADP
fnp-3317	64	46	cognitive	cognitive	ADJ
fnp-3317	64	47	decline	decline	NOUN
fnp-3317	64	48	and	and	CCONJ
fnp-3317	64	49	ad	ad	NOUN
fnp-3317	64	50	(	(	PUNCT
fnp-3317	64	51	wingo	wingo	NOUN
fnp-3317	64	52	et	et	PROPN
fnp-3317	64	53	al	al	PROPN
fnp-3317	64	54	.	.	PROPN
fnp-3317	64	55	,	,	PUNCT
fnp-3317	64	56	2020	2020	NUM
fnp-3317	64	57	)	)	PUNCT
fnp-3317	64	58	.	.	PUNCT
fnp-3317	65	1	here	here	ADV
fnp-3317	65	2	,	,	PUNCT
fnp-3317	65	3	the	the	DET
fnp-3317	65	4	investigators	investigator	NOUN
fnp-3317	65	5	performed	perform	VERB
fnp-3317	65	6	a	a	DET
fnp-3317	65	7	proteome	proteome	ADJ
fnp-3317	65	8	-	-	PUNCT
fnp-3317	65	9	wide	wide	ADJ
fnp-3317	65	10	association	association	NOUN
fnp-3317	65	11	study	study	NOUN
fnp-3317	65	12	(	(	PUNCT
fnp-3317	65	13	pwas	pwas	NUM
fnp-3317	65	14	)	)	PUNCT
fnp-3317	65	15	,	,	PUNCT
fnp-3317	65	16	which	which	PRON
fnp-3317	65	17	is	be	AUX
fnp-3317	65	18	similar	similar	ADJ
fnp-3317	65	19	to	to	ADP
fnp-3317	65	20	a	a	DET
fnp-3317	65	21	genome	genome	NOUN
fnp-3317	65	22	-	-	PUNCT
fnp-3317	65	23	wide	wide	ADJ
fnp-3317	65	24	association	association	NOUN
fnp-3317	65	25	study	study	NOUN
fnp-3317	65	26	(	(	PUNCT
fnp-3317	65	27	gwas	gwas	PROPN
fnp-3317	65	28	)	)	PUNCT
fnp-3317	65	29	,	,	PUNCT
fnp-3317	65	30	to	to	PART
fnp-3317	65	31	look	look	VERB
fnp-3317	65	32	more	more	ADV
fnp-3317	65	33	broadly	broadly	ADV
fnp-3317	65	34	at	at	ADP
fnp-3317	65	35	relevant	relevant	ADJ
fnp-3317	65	36	neuropathological	neuropathological	ADJ
fnp-3317	65	37	changes	change	NOUN
fnp-3317	65	38	,	,	PUNCT
fnp-3317	65	39	including	include	VERB
fnp-3317	65	40	amyloid	amyloid	NOUN
fnp-3317	65	41	-	-	PUNCT
fnp-3317	65	42	beta	beta	NOUN
fnp-3317	65	43	deposition	deposition	NOUN
fnp-3317	65	44	,	,	PUNCT
fnp-3317	65	45	neurofibrillary	neurofibrillary	ADJ
fnp-3317	65	46	tangles	tangle	NOUN
fnp-3317	65	47	,	,	PUNCT
fnp-3317	65	48	infarcts	infarct	VERB
fnp-3317	65	49	(	(	PUNCT
fnp-3317	65	50	both	both	CCONJ
fnp-3317	65	51	macro	macro	NOUN
fnp-3317	65	52	and	and	CCONJ
fnp-3317	65	53	microinfarcts	microinfarct	NOUN
fnp-3317	65	54	)	)	PUNCT
fnp-3317	65	55	,	,	PUNCT
fnp-3317	65	56	cerebral	cerebral	ADJ
fnp-3317	65	57	amyloid	amyloid	NOUN
fnp-3317	65	58	angiopathy	angiopathy	NOUN
fnp-3317	65	59	,	,	PUNCT
fnp-3317	65	60	tar	tar	NOUN
fnp-3317	65	61	dna	dna	NOUN
fnp-3317	65	62	-	-	PUNCT
fnp-3317	65	63	binding	bind	VERB
fnp-3317	65	64	protein	protein	NOUN
fnp-3317	65	65	43	43	NUM
fnp-3317	65	66	(	(	PUNCT
fnp-3317	65	67	tdp-43	tdp-43	PROPN
fnp-3317	65	68	,	,	PUNCT
fnp-3317	65	69	transactive	transactive	ADJ
fnp-3317	65	70	response	response	NOUN
fnp-3317	65	71	dna	dna	NOUN
fnp-3317	65	72	binding	bind	VERB
fnp-3317	65	73	protein	protein	NOUN
fnp-3317	65	74	43	43	NUM
fnp-3317	65	75	kda	kda	NOUN
fnp-3317	65	76	)	)	PUNCT
fnp-3317	65	77	,	,	PUNCT
fnp-3317	65	78	lewy	lewy	PROPN
fnp-3317	65	79	body	body	PROPN
fnp-3317	65	80	pathology	pathology	NOUN
fnp-3317	65	81	,	,	PUNCT
fnp-3317	65	82	hippocampal	hippocampal	ADJ
fnp-3317	65	83	sclerosis	sclerosis	NOUN
fnp-3317	65	84	,	,	PUNCT
fnp-3317	65	85	and	and	CCONJ
fnp-3317	65	86	atherosclerosis	atherosclerosis	NOUN
fnp-3317	65	87	.	.	PUNCT
fnp-3317	66	1	out	out	ADP
fnp-3317	66	2	of	of	ADP
fnp-3317	66	3	this	this	DET
fnp-3317	66	4	analysis	analysis	NOUN
fnp-3317	66	5	,	,	PUNCT
fnp-3317	66	6	114	114	NUM
fnp-3317	66	7	proteins	protein	NOUN
fnp-3317	66	8	emerged	emerge	VERB
fnp-3317	66	9	,	,	PUNCT
fnp-3317	66	10	independently	independently	ADV
fnp-3317	66	11	of	of	ADP
fnp-3317	66	12	cerebrovascular	cerebrovascular	ADJ
fnp-3317	66	13	risk	risk	NOUN
fnp-3317	66	14	factors	factor	NOUN
fnp-3317	66	15	(	(	PUNCT
fnp-3317	66	16	e.g.	e.g.	ADV
fnp-3317	66	17	,	,	PUNCT
fnp-3317	66	18	hypertension	hypertension	NOUN
fnp-3317	66	19	,	,	PUNCT
fnp-3317	66	20	diabetes	diabetes	NOUN
fnp-3317	66	21	,	,	PUNCT
fnp-3317	66	22	smoking	smoking	NOUN
fnp-3317	66	23	;	;	PUNCT
fnp-3317	66	24	figure	figure	NOUN
fnp-3317	66	25	3	3	NUM
fnp-3317	66	26	)	)	PUNCT
fnp-3317	66	27	.	.	PUNCT
fnp-3317	67	1	strikingly	strikingly	ADV
fnp-3317	67	2	,	,	PUNCT
fnp-3317	67	3	many	many	ADJ
fnp-3317	67	4	were	be	AUX
fnp-3317	67	5	from	from	ADP
fnp-3317	67	6	oligodendrocytes	oligodendrocyte	NOUN
fnp-3317	67	7	involved	involve	VERB
fnp-3317	67	8	in	in	ADP
fnp-3317	67	9	myelination	myelination	NOUN
fnp-3317	67	10	.	.	PUNCT
fnp-3317	68	1	other	other	ADJ
fnp-3317	68	2	genes	gene	NOUN
fnp-3317	68	3	were	be	AUX
fnp-3317	68	4	involved	involve	VERB
fnp-3317	68	5	in	in	ADP
fnp-3317	68	6	mrna	mrna	PROPN
fnp-3317	68	7	processing	processing	NOUN
fnp-3317	68	8	and	and	CCONJ
fnp-3317	68	9	splicing	splicing	NOUN
fnp-3317	68	10	.	.	PUNCT
fnp-3317	69	1	they	they	PRON
fnp-3317	69	2	performed	perform	VERB
fnp-3317	69	3	co	co	ADJ
fnp-3317	69	4	-	-	NOUN
fnp-3317	69	5	expression	expression	ADJ
fnp-3317	69	6	network	network	NOUN
fnp-3317	69	7	analysis	analysis	NOUN
fnp-3317	69	8	and	and	CCONJ
fnp-3317	69	9	31	31	NUM
fnp-3317	69	10	modules	module	NOUN
fnp-3317	69	11	were	be	AUX
fnp-3317	69	12	identified	identify	VERB
fnp-3317	69	13	,	,	PUNCT
fnp-3317	69	14	with	with	ADP
fnp-3317	69	15	five	five	NUM
fnp-3317	69	16	being	be	AUX
fnp-3317	69	17	linked	link	VERB
fnp-3317	69	18	independently	independently	ADV
fnp-3317	69	19	to	to	ADP
fnp-3317	69	20	cerebral	cerebral	ADJ
fnp-3317	69	21	atherosclerosis	atherosclerosis	NOUN
fnp-3317	69	22	.	.	PUNCT
fnp-3317	70	1	this	this	DET
fnp-3317	70	2	analysis	analysis	NOUN
fnp-3317	70	3	pointed	point	VERB
fnp-3317	70	4	to	to	ADP
fnp-3317	70	5	oligodendrocyte	oligodendrocyte	ADJ
fnp-3317	70	6	function	function	NOUN
fnp-3317	70	7	alongside	alongside	ADP
fnp-3317	70	8	downregulation	downregulation	NOUN
fnp-3317	70	9	of	of	ADP
fnp-3317	70	10	mrna	mrna	PROPN
fnp-3317	70	11	processing	processing	NOUN
fnp-3317	70	12	in	in	ADP
fnp-3317	70	13	neurons	neuron	NOUN
fnp-3317	70	14	and	and	CCONJ
fnp-3317	70	15	astrocytes	astrocyte	NOUN
fnp-3317	70	16	with	with	ADP
fnp-3317	70	17	impaired	impaired	ADJ
fnp-3317	70	18	synaptic	synaptic	ADJ
fnp-3317	70	19	functioning	functioning	NOUN
fnp-3317	70	20	in	in	ADP
fnp-3317	70	21	brains	brain	NOUN
fnp-3317	70	22	of	of	ADP
fnp-3317	70	23	individuals	individual	NOUN
fnp-3317	70	24	with	with	ADP
fnp-3317	70	25	cerebral	cerebral	ADJ
fnp-3317	70	26	atherosclerosis	atherosclerosis	NOUN
fnp-3317	70	27	.	.	PUNCT
fnp-3317	71	1	this	this	PRON
fnp-3317	71	2	may	may	AUX
fnp-3317	71	3	be	be	AUX
fnp-3317	71	4	related	relate	VERB
fnp-3317	71	5	to	to	ADP
fnp-3317	71	6	another	another	DET
fnp-3317	71	7	finding	finding	NOUN
fnp-3317	71	8	of	of	ADP
fnp-3317	71	9	higher	high	ADJ
fnp-3317	71	10	levels	level	NOUN
fnp-3317	71	11	of	of	ADP
fnp-3317	71	12	neurofilament	neurofilament	ADJ
fnp-3317	71	13	light	light	NOUN
fnp-3317	71	14	(	(	PUNCT
fnp-3317	71	15	nfl	nfl	PROPN
fnp-3317	71	16	)	)	PUNCT
fnp-3317	71	17	and	and	CCONJ
fnp-3317	71	18	medium	medium	NOUN
fnp-3317	71	19	(	(	PUNCT
fnp-3317	71	20	nfm	nfm	PROPN
fnp-3317	71	21	)	)	PUNCT
fnp-3317	71	22	which	which	PRON
fnp-3317	71	23	were	be	AUX
fnp-3317	71	24	higher	high	ADJ
fnp-3317	71	25	in	in	ADP
fnp-3317	71	26	cases	case	NOUN
fnp-3317	71	27	with	with	ADP
fnp-3317	71	28	atherosclerosis	atherosclerosis	NOUN
fnp-3317	71	29	,	,	PUNCT
fnp-3317	71	30	perhaps	perhaps	ADV
fnp-3317	71	31	reflecting	reflect	VERB
fnp-3317	71	32	axonal	axonal	ADJ
fnp-3317	71	33	injury	injury	NOUN
fnp-3317	71	34	.	.	PUNCT
fnp-3317	72	1	this	this	DET
fnp-3317	72	2	study	study	NOUN
fnp-3317	72	3	will	will	AUX
fnp-3317	72	4	drive	drive	VERB
fnp-3317	72	5	continued	continued	ADJ
fnp-3317	72	6	research	research	NOUN
fnp-3317	72	7	into	into	ADP
fnp-3317	72	8	the	the	DET
fnp-3317	72	9	effects	effect	NOUN
fnp-3317	72	10	of	of	ADP
fnp-3317	72	11	cerebral	cerebral	ADJ
fnp-3317	72	12	atherosclerosis	atherosclerosis	NOUN
fnp-3317	72	13	on	on	ADP
fnp-3317	72	14	the	the	DET
fnp-3317	72	15	brain	brain	NOUN
fnp-3317	72	16	proteome	proteome	NOUN
fnp-3317	72	17	and	and	CCONJ
fnp-3317	72	18	their	their	PRON
fnp-3317	72	19	contribution	contribution	NOUN
fnp-3317	72	20	to	to	ADP
fnp-3317	72	21	ad	ad	NOUN
fnp-3317	72	22	.	.	PUNCT
fnp-3317	73	1	figure	figure	NOUN
fnp-3317	73	2	3	3	NUM
fnp-3317	73	3	.	.	PUNCT
fnp-3317	74	1	co	co	ADJ
fnp-3317	74	2	-	-	NOUN
fnp-3317	74	3	expression	expression	ADJ
fnp-3317	74	4	network	network	NOUN
fnp-3317	74	5	analysis	analysis	NOUN
fnp-3317	74	6	of	of	ADP
fnp-3317	74	7	protein	protein	NOUN
fnp-3317	74	8	modules	module	NOUN
fnp-3317	74	9	in	in	ADP
fnp-3317	74	10	post	post	ADJ
fnp-3317	74	11	-	-	ADJ
fnp-3317	74	12	mortem	mortem	ADJ
fnp-3317	74	13	human	human	ADJ
fnp-3317	74	14	brain	brain	NOUN
fnp-3317	74	15	.	.	PUNCT
fnp-3317	75	1	a	a	PRON
fnp-3317	75	2	,	,	PUNCT
fnp-3317	75	3	b.	b.	PROPN
fnp-3317	76	1	a	a	DET
fnp-3317	76	2	total	total	NOUN
fnp-3317	76	3	of	of	ADP
fnp-3317	76	4	31	31	NUM
fnp-3317	76	5	modules	module	NOUN
fnp-3317	76	6	were	be	AUX
fnp-3317	76	7	identified	identify	VERB
fnp-3317	76	8	and	and	CCONJ
fnp-3317	76	9	protein	protein	NOUN
fnp-3317	76	10	signatures	signature	NOUN
fnp-3317	76	11	mapped	map	VERB
fnp-3317	76	12	to	to	ADP
fnp-3317	76	13	cell	cell	NOUN
fnp-3317	76	14	type	type	NOUN
fnp-3317	76	15	.	.	PUNCT
fnp-3317	77	1	c.	c.	NOUN
fnp-3317	78	1	these	these	DET
fnp-3317	78	2	modules	module	NOUN
fnp-3317	78	3	were	be	AUX
fnp-3317	78	4	then	then	ADV
fnp-3317	78	5	associated	associate	VERB
fnp-3317	78	6	with	with	ADP
fnp-3317	78	7	neuropathological	neuropathological	ADJ
fnp-3317	78	8	outcomes	outcome	NOUN
fnp-3317	78	9	.	.	PUNCT
fnp-3317	79	1	d.	d.	PROPN
fnp-3317	79	2	differences	difference	NOUN
fnp-3317	79	3	in	in	ADP
fnp-3317	79	4	module	module	NOUN
fnp-3317	79	5	eigen	eigen	NOUN
fnp-3317	79	6	proteins	protein	NOUN
fnp-3317	79	7	were	be	AUX
fnp-3317	79	8	seen	see	VERB
fnp-3317	79	9	modules	module	NOUN
fnp-3317	79	10	3	3	NUM
fnp-3317	79	11	and	and	CCONJ
fnp-3317	79	12	9	9	NUM
fnp-3317	79	13	for	for	ADP
fnp-3317	79	14	atherosclerosis	atherosclerosis	NOUN
fnp-3317	79	15	and	and	CCONJ
fnp-3317	79	16	alzheimer	alzheimer	NOUN
fnp-3317	79	17	disease	disease	NOUN
fnp-3317	79	18	-	-	PUNCT
fnp-3317	79	19	related	relate	VERB
fnp-3317	79	20	dementia	dementia	NOUN
fnp-3317	79	21	.	.	PUNCT
fnp-3317	80	1	images	image	NOUN
fnp-3317	80	2	curtesy	curtesy	ADV
fnp-3317	80	3	of	of	ADP
fnp-3317	80	4	drs	dr	NOUN
fnp-3317	80	5	.	.	PUNCT
fnp-3317	81	1	thomas	thomas	PROPN
fnp-3317	81	2	wingo	wingo	PROPN
fnp-3317	81	3	,	,	PUNCT
fnp-3317	81	4	aliza	aliza	PROPN
fnp-3317	81	5	wingo	wingo	PROPN
fnp-3317	81	6	,	,	PUNCT
fnp-3317	81	7	nicholas	nicholas	PROPN
fnp-3317	81	8	seyfried	seyfried	PROPN
fnp-3317	81	9	,	,	PUNCT
fnp-3317	81	10	allan	allan	PROPN
fnp-3317	81	11	i.	i.	PROPN
fnp-3317	81	12	levey	levey	PROPN
fnp-3317	81	13	(	(	PUNCT
fnp-3317	81	14	emory	emory	PROPN
fnp-3317	81	15	university	university	PROPN
fnp-3317	81	16	school	school	NOUN
fnp-3317	81	17	of	of	ADP
fnp-3317	81	18	medicine	medicine	NOUN
fnp-3317	81	19	)	)	PUNCT
fnp-3317	81	20	.	.	PUNCT
fnp-3317	82	1	4	4	X
fnp-3317	82	2	.	.	X
fnp-3317	82	3	proteomic	proteomic	ADJ
fnp-3317	82	4	analysis	analysis	NOUN
fnp-3317	82	5	:	:	PUNCT
fnp-3317	82	6	a	a	DET
fnp-3317	82	7	high	high	ADJ
fnp-3317	82	8	-	-	PUNCT
fnp-3317	82	9	resolution	resolution	NOUN
fnp-3317	82	10	quantitative	quantitative	ADJ
fnp-3317	82	11	map	map	NOUN
fnp-3317	82	12	of	of	ADP
fnp-3317	82	13	post	post	ADJ
fnp-3317	82	14	-	-	ADJ
fnp-3317	82	15	translational	translational	ADJ
fnp-3317	82	16	modifications	modification	NOUN
fnp-3317	82	17	of	of	ADP
fnp-3317	82	18	tau	tau	PROPN
fnp-3317	82	19	proteoforms	proteoform	VERB
fnp-3317	82	20	neurofibrillary	neurofibrillary	ADJ
fnp-3317	82	21	tangles	tangle	NOUN
fnp-3317	82	22	exist	exist	VERB
fnp-3317	82	23	in	in	ADP
fnp-3317	82	24	a	a	DET
fnp-3317	82	25	spectrum	spectrum	NOUN
fnp-3317	82	26	of	of	ADP
fnp-3317	82	27	morphological	morphological	ADJ
fnp-3317	82	28	forms	form	NOUN
fnp-3317	82	29	that	that	PRON
fnp-3317	82	30	are	be	AUX
fnp-3317	82	31	immediately	immediately	ADV
fnp-3317	82	32	recognizable	recognizable	ADJ
fnp-3317	82	33	using	use	VERB
fnp-3317	82	34	immunohistochemistry	immunohistochemistry	NOUN
fnp-3317	82	35	with	with	ADP
fnp-3317	82	36	antisera	antisera	NOUN
fnp-3317	82	37	targeting	target	VERB
fnp-3317	82	38	hyperphosphorylated	hyperphosphorylate	VERB
fnp-3317	82	39	tau	tau	PROPN
fnp-3317	82	40	(	(	PUNCT
fnp-3317	82	41	p	p	PROPN
fnp-3317	82	42	-	-	PUNCT
fnp-3317	82	43	tau	tau	NOUN
fnp-3317	82	44	)	)	PUNCT
fnp-3317	82	45	.	.	PUNCT
fnp-3317	83	1	the	the	DET
fnp-3317	83	2	earliest	early	ADJ
fnp-3317	83	3	detectable	detectable	ADJ
fnp-3317	83	4	neurofibrillary	neurofibrillary	ADJ
fnp-3317	83	5	change	change	NOUN
fnp-3317	83	6	is	be	AUX
fnp-3317	83	7	the	the	DET
fnp-3317	83	8	presence	presence	NOUN
fnp-3317	83	9	faint	faint	ADJ
fnp-3317	83	10	granular	granular	ADJ
fnp-3317	83	11	p	p	PROPN
fnp-3317	83	12	-	-	PUNCT
fnp-3317	83	13	tau	tau	NOUN
fnp-3317	83	14	labeling	labeling	NOUN
fnp-3317	83	15	in	in	ADP
fnp-3317	83	16	pre	pre	NOUN
fnp-3317	83	17	-	-	NOUN
fnp-3317	83	18	tangles	tangle	NOUN
fnp-3317	83	19	;	;	PUNCT
fnp-3317	83	20	this	this	DET
fnp-3317	83	21	staining	stain	VERB
fnp-3317	83	22	accumulates	accumulate	VERB
fnp-3317	83	23	and	and	CCONJ
fnp-3317	83	24	coalesces	coalesce	VERB
fnp-3317	83	25	into	into	ADP
fnp-3317	83	26	intracellular	intracellular	ADJ
fnp-3317	83	27	tangles	tangle	NOUN
fnp-3317	83	28	that	that	PRON
fnp-3317	83	29	eventually	eventually	ADV
fnp-3317	83	30	become	become	VERB
fnp-3317	83	31	extracellular	extracellular	ADJ
fnp-3317	83	32	(	(	PUNCT
fnp-3317	83	33	“	"	PUNCT
fnp-3317	83	34	tombstone	tombstone	NOUN
fnp-3317	83	35	”	"	PUNCT
fnp-3317	83	36	or	or	CCONJ
fnp-3317	83	37	“	"	PUNCT
fnp-3317	83	38	ghost	ghost	NOUN
fnp-3317	83	39	”	"	PUNCT
fnp-3317	83	40	)	)	PUNCT
fnp-3317	83	41	tangles	tangle	NOUN
fnp-3317	83	42	following	follow	VERB
fnp-3317	83	43	neuronal	neuronal	ADJ
fnp-3317	83	44	death	death	NOUN
fnp-3317	83	45	.	.	PUNCT
fnp-3317	84	1	understanding	understand	VERB
fnp-3317	84	2	the	the	DET
fnp-3317	84	3	molecular	molecular	ADJ
fnp-3317	84	4	events	event	NOUN
fnp-3317	84	5	that	that	PRON
fnp-3317	84	6	correspond	correspond	VERB
fnp-3317	84	7	to	to	ADP
fnp-3317	84	8	this	this	DET
fnp-3317	84	9	sequence	sequence	NOUN
fnp-3317	84	10	would	would	AUX
fnp-3317	84	11	be	be	AUX
fnp-3317	84	12	extremely	extremely	ADV
fnp-3317	84	13	helpful	helpful	ADJ
fnp-3317	84	14	for	for	ADP
fnp-3317	84	15	developing	develop	VERB
fnp-3317	84	16	the	the	DET
fnp-3317	84	17	next	next	ADJ
fnp-3317	84	18	generation	generation	NOUN
fnp-3317	84	19	of	of	ADP
fnp-3317	84	20	diagnostics	diagnostic	NOUN
fnp-3317	84	21	(	(	PUNCT
fnp-3317	84	22	see	see	VERB
fnp-3317	84	23	below	below	ADV
fnp-3317	84	24	)	)	PUNCT
fnp-3317	84	25	and	and	CCONJ
fnp-3317	84	26	therapeutics	therapeutic	NOUN
fnp-3317	84	27	.	.	PUNCT
fnp-3317	85	1	the	the	DET
fnp-3317	85	2	pathobiology	pathobiology	NOUN
fnp-3317	85	3	of	of	ADP
fnp-3317	85	4	tau	tau	PROPN
fnp-3317	85	5	pathology	pathology	NOUN
fnp-3317	85	6	is	be	AUX
fnp-3317	85	7	complex	complex	ADJ
fnp-3317	85	8	,	,	PUNCT
fnp-3317	85	9	with	with	SCONJ
fnp-3317	85	10	multiple	multiple	ADJ
fnp-3317	85	11	tau	tau	PROPN
fnp-3317	85	12	isoforms	isoform	VERB
fnp-3317	85	13	undergoing	undergo	VERB
fnp-3317	85	14	innumerable	innumerable	ADJ
fnp-3317	85	15	secondary	secondary	ADJ
fnp-3317	85	16	structural	structural	ADJ
fnp-3317	85	17	modifications	modification	NOUN
fnp-3317	85	18	in	in	ADP
fnp-3317	85	19	disease	disease	NOUN
fnp-3317	85	20	states	state	NOUN
fnp-3317	85	21	beyond	beyond	ADP
fnp-3317	85	22	just	just	ADV
fnp-3317	85	23	hyperphosphorylation	hyperphosphorylation	NOUN
fnp-3317	85	24	,	,	PUNCT
fnp-3317	85	25	including	include	VERB
fnp-3317	85	26	truncation	truncation	NOUN
fnp-3317	85	27	,	,	PUNCT
fnp-3317	85	28	acetylation	acetylation	NOUN
fnp-3317	85	29	,	,	PUNCT
fnp-3317	85	30	ubiquitination	ubiquitination	NOUN
fnp-3317	85	31	,	,	PUNCT
fnp-3317	85	32	glycosylation	glycosylation	NOUN
fnp-3317	85	33	and	and	CCONJ
fnp-3317	85	34	methylation	methylation	NOUN
fnp-3317	85	35	.	.	PUNCT
fnp-3317	86	1	it	it	PRON
fnp-3317	86	2	has	have	AUX
fnp-3317	86	3	been	be	AUX
fnp-3317	86	4	challenging	challenge	VERB
fnp-3317	86	5	to	to	PART
fnp-3317	86	6	temporally	temporally	ADV
fnp-3317	86	7	map	map	VERB
fnp-3317	86	8	the	the	DET
fnp-3317	86	9	order	order	NOUN
fnp-3317	86	10	of	of	ADP
fnp-3317	86	11	these	these	DET
fnp-3317	86	12	events	event	NOUN
fnp-3317	86	13	using	use	VERB
fnp-3317	86	14	traditional	traditional	ADJ
fnp-3317	86	15	approaches	approach	NOUN
fnp-3317	86	16	(	(	PUNCT
fnp-3317	86	17	e.g.	e.g.	ADV
fnp-3317	86	18	,	,	PUNCT
fnp-3317	86	19	phospho	phospho	ADJ
fnp-3317	86	20	-	-	PUNCT
fnp-3317	86	21	specific	specific	ADJ
fnp-3317	86	22	tau	tau	PROPN
fnp-3317	86	23	antisera	antisera	NOUN
fnp-3317	86	24	-	-	PUNCT
fnp-3317	86	25	based	base	VERB
fnp-3317	86	26	methods	method	NOUN
fnp-3317	86	27	)	)	PUNCT
fnp-3317	86	28	which	which	PRON
fnp-3317	86	29	lack	lack	VERB
fnp-3317	86	30	the	the	DET
fnp-3317	86	31	ability	ability	NOUN
fnp-3317	86	32	to	to	PART
fnp-3317	86	33	synchronously	synchronously	ADV
fnp-3317	86	34	and	and	CCONJ
fnp-3317	86	35	comprehensively	comprehensively	ADV
fnp-3317	86	36	detect	detect	VERB
fnp-3317	86	37	these	these	DET
fnp-3317	86	38	critical	critical	ADJ
fnp-3317	86	39	changes	change	NOUN
fnp-3317	86	40	.	.	PUNCT
fnp-3317	87	1	in	in	ADP
fnp-3317	87	2	the	the	DET
fnp-3317	87	3	last	last	ADJ
fnp-3317	87	4	proteomics	proteomic	NOUN
fnp-3317	87	5	paper	paper	NOUN
fnp-3317	87	6	,	,	PUNCT
fnp-3317	87	7	published	publish	VERB
fnp-3317	87	8	in	in	ADP
fnp-3317	87	9	cell	cell	NOUN
fnp-3317	87	10	in	in	ADP
fnp-3317	87	11	november	november	PROPN
fnp-3317	87	12	of	of	ADP
fnp-3317	87	13	2020	2020	NUM
fnp-3317	87	14	,	,	PUNCT
fnp-3317	87	15	a	a	DET
fnp-3317	87	16	powerful	powerful	ADJ
fnp-3317	87	17	study	study	NOUN
fnp-3317	87	18	,	,	PUNCT
fnp-3317	87	19	led	lead	VERB
fnp-3317	87	20	by	by	ADP
fnp-3317	87	21	dr	dr	PROPN
fnp-3317	87	22	.	.	PROPN
fnp-3317	87	23	judith	judith	PROPN
fnp-3317	87	24	steene	steene	PROPN
fnp-3317	87	25	at	at	ADP
fnp-3317	87	26	boston	boston	PROPN
fnp-3317	87	27	children	children	PROPN
fnp-3317	87	28	’s	’s	PART
fnp-3317	87	29	hospital	hospital	NOUN
fnp-3317	87	30	,	,	PUNCT
fnp-3317	87	31	detailed	detail	VERB
fnp-3317	87	32	their	their	PRON
fnp-3317	87	33	focused	focused	ADJ
fnp-3317	87	34	analysis	analysis	NOUN
fnp-3317	87	35	that	that	PRON
fnp-3317	87	36	was	be	AUX
fnp-3317	87	37	entirely	entirely	ADV
fnp-3317	87	38	directed	direct	VERB
fnp-3317	87	39	towards	towards	ADP
fnp-3317	87	40	the	the	DET
fnp-3317	87	41	tau	tau	PROPN
fnp-3317	87	42	protein	protein	NOUN
fnp-3317	87	43	(	(	PUNCT
fnp-3317	87	44	wesseling	wesseling	NOUN
fnp-3317	87	45	et	et	NOUN
fnp-3317	87	46	al	al	PROPN
fnp-3317	87	47	.	.	PROPN
fnp-3317	87	48	,	,	PUNCT
fnp-3317	87	49	2020	2020	NUM
fnp-3317	87	50	)	)	PUNCT
fnp-3317	87	51	.	.	PUNCT
fnp-3317	88	1	they	they	PRON
fnp-3317	88	2	deployed	deploy	VERB
fnp-3317	88	3	a	a	DET
fnp-3317	88	4	previously	previously	ADV
fnp-3317	88	5	published	publish	VERB
fnp-3317	88	6	mass	mass	NOUN
fnp-3317	88	7	spectrometry	spectrometry	NOUN
fnp-3317	88	8	-	-	PUNCT
fnp-3317	88	9	based	base	VERB
fnp-3317	88	10	assay	assay	NOUN
fnp-3317	88	11	,	,	PUNCT
fnp-3317	88	12	that	that	SCONJ
fnp-3317	88	13	they	they	PRON
fnp-3317	88	14	term	term	VERB
fnp-3317	88	15	“	"	PUNCT
fnp-3317	88	16	flexi	flexi	NOUN
fnp-3317	88	17	-	-	PUNCT
fnp-3317	88	18	tau	tau	PROPN
fnp-3317	88	19	”	"	PUNCT
fnp-3317	88	20	(	(	PUNCT
fnp-3317	88	21	mair	mair	PROPN
fnp-3317	88	22	et	et	PROPN
fnp-3317	88	23	al	al	PROPN
fnp-3317	88	24	.	.	PROPN
fnp-3317	88	25	,	,	PUNCT
fnp-3317	88	26	2016	2016	NUM
fnp-3317	88	27	)	)	PUNCT
fnp-3317	88	28	,	,	PUNCT
fnp-3317	88	29	which	which	PRON
fnp-3317	88	30	allowed	allow	VERB
fnp-3317	88	31	them	they	PRON
fnp-3317	88	32	to	to	PART
fnp-3317	88	33	generate	generate	VERB
fnp-3317	88	34	a	a	DET
fnp-3317	88	35	high	high	ADJ
fnp-3317	88	36	-	-	PUNCT
fnp-3317	88	37	resolution	resolution	NOUN
fnp-3317	88	38	quantitative	quantitative	ADJ
fnp-3317	88	39	proteomic	proteomic	ADJ
fnp-3317	88	40	map	map	NOUN
fnp-3317	88	41	of	of	ADP
fnp-3317	88	42	95	95	NUM
fnp-3317	88	43	post	post	ADJ
fnp-3317	88	44	-	-	ADJ
fnp-3317	88	45	translational	translational	ADJ
fnp-3317	88	46	modifications	modification	NOUN
fnp-3317	88	47	on	on	ADP
fnp-3317	88	48	multiple	multiple	ADJ
fnp-3317	88	49	tau	tau	PROPN
fnp-3317	88	50	isoforms	isoform	NOUN
fnp-3317	88	51	from	from	ADP
fnp-3317	88	52	91	91	NUM
fnp-3317	88	53	human	human	ADJ
fnp-3317	88	54	post	post	ADJ
fnp-3317	88	55	-	-	ADJ
fnp-3317	88	56	mortem	mortem	ADJ
fnp-3317	88	57	brains	brain	NOUN
fnp-3317	88	58	.	.	PUNCT
fnp-3317	89	1	they	they	PRON
fnp-3317	89	2	then	then	ADV
fnp-3317	89	3	used	use	VERB
fnp-3317	89	4	unsupervised	unsupervised	ADJ
fnp-3317	89	5	analyses	analysis	NOUN
fnp-3317	89	6	to	to	PART
fnp-3317	89	7	predict	predict	VERB
fnp-3317	89	8	sequential	sequential	ADJ
fnp-3317	89	9	addition	addition	NOUN
fnp-3317	89	10	of	of	ADP
fnp-3317	89	11	modifications	modification	NOUN
fnp-3317	89	12	.	.	PUNCT
fnp-3317	90	1	they	they	PRON
fnp-3317	90	2	found	find	VERB
fnp-3317	90	3	that	that	SCONJ
fnp-3317	90	4	while	while	SCONJ
fnp-3317	90	5	there	there	PRON
fnp-3317	90	6	is	be	VERB
fnp-3317	90	7	a	a	DET
fnp-3317	90	8	great	great	ADJ
fnp-3317	90	9	degree	degree	NOUN
fnp-3317	90	10	of	of	ADP
fnp-3317	90	11	heterogeneity	heterogeneity	NOUN
fnp-3317	90	12	,	,	PUNCT
fnp-3317	90	13	there	there	PRON
fnp-3317	90	14	appears	appear	VERB
fnp-3317	90	15	to	to	PART
fnp-3317	90	16	be	be	AUX
fnp-3317	90	17	a	a	DET
fnp-3317	90	18	minimal	minimal	ADJ
fnp-3317	90	19	set	set	NOUN
fnp-3317	90	20	of	of	ADP
fnp-3317	90	21	modifications	modification	NOUN
fnp-3317	90	22	that	that	PRON
fnp-3317	90	23	develop	develop	VERB
fnp-3317	90	24	in	in	ADP
fnp-3317	90	25	a	a	DET
fnp-3317	90	26	processive	processive	ADJ
fnp-3317	90	27	fashion	fashion	NOUN
fnp-3317	90	28	and	and	CCONJ
fnp-3317	90	29	are	be	AUX
fnp-3317	90	30	associated	associate	VERB
fnp-3317	90	31	with	with	ADP
fnp-3317	90	32	tissue	tissue	NOUN
fnp-3317	90	33	fractions	fraction	NOUN
fnp-3317	90	34	associated	associate	VERB
fnp-3317	90	35	with	with	ADP
fnp-3317	90	36	disease	disease	NOUN
fnp-3317	90	37	stage	stage	NOUN
fnp-3317	90	38	as	as	ADV
fnp-3317	90	39	well	well	ADV
fnp-3317	90	40	as	as	ADP
fnp-3317	90	41	tau	tau	NOUN
fnp-3317	90	42	seeding	seed	VERB
fnp-3317	90	43	activity	activity	NOUN
fnp-3317	90	44	.	.	PUNCT
fnp-3317	91	1	the	the	DET
fnp-3317	91	2	analysis	analysis	NOUN
fnp-3317	91	3	also	also	ADV
fnp-3317	91	4	highlighted	highlight	VERB
fnp-3317	91	5	a	a	DET
fnp-3317	91	6	specific	specific	ADJ
fnp-3317	91	7	alternatively	alternatively	ADV
fnp-3317	91	8	spliced	splice	VERB
fnp-3317	91	9	tau	tau	PROPN
fnp-3317	91	10	isoform	isoform	NOUN
fnp-3317	91	11	with	with	ADP
fnp-3317	91	12	four	four	NUM
fnp-3317	91	13	microtubule	microtubule	NOUN
fnp-3317	91	14	binding	bind	VERB
fnp-3317	91	15	domain	domain	NOUN
fnp-3317	91	16	repeats	repeat	NOUN
fnp-3317	91	17	(	(	PUNCT
fnp-3317	91	18	4r	4r	NOUN
fnp-3317	91	19	)	)	PUNCT
fnp-3317	91	20	,	,	PUNCT
fnp-3317	91	21	but	but	CCONJ
fnp-3317	91	22	lacking	lack	VERB
fnp-3317	91	23	n	n	CCONJ
fnp-3317	91	24	-	-	PUNCT
fnp-3317	91	25	terminal	terminal	ADJ
fnp-3317	91	26	domain	domain	NOUN
fnp-3317	91	27	inserts	insert	NOUN
fnp-3317	91	28	(	(	PUNCT
fnp-3317	91	29	0n	0n	NUM
fnp-3317	91	30	)	)	PUNCT
fnp-3317	91	31	.	.	PUNCT
fnp-3317	92	1	the	the	DET
fnp-3317	92	2	0n4r	0n4r	NOUN
fnp-3317	92	3	isoform	isoform	NOUN
fnp-3317	92	4	is	be	AUX
fnp-3317	92	5	highly	highly	ADV
fnp-3317	92	6	overrepresented	overrepresented	ADJ
fnp-3317	92	7	in	in	ADP
fnp-3317	92	8	aggregates	aggregate	NOUN
fnp-3317	92	9	isolated	isolate	VERB
fnp-3317	92	10	from	from	ADP
fnp-3317	92	11	early	early	ADJ
fnp-3317	92	12	disease	disease	NOUN
fnp-3317	92	13	stages	stage	NOUN
fnp-3317	92	14	alongside	alongside	ADP
fnp-3317	92	15	modifications	modification	NOUN
fnp-3317	92	16	associated	associate	VERB
fnp-3317	92	17	with	with	ADP
fnp-3317	92	18	increased	increase	VERB
fnp-3317	92	19	negative	negative	ADJ
fnp-3317	92	20	charge	charge	NOUN
fnp-3317	92	21	in	in	ADP
fnp-3317	92	22	the	the	DET
fnp-3317	92	23	proline	proline	NOUN
fnp-3317	92	24	-	-	PUNCT
fnp-3317	92	25	rich	rich	ADJ
fnp-3317	92	26	region	region	NOUN
fnp-3317	92	27	and	and	CCONJ
fnp-3317	92	28	decreased	decrease	VERB
fnp-3317	92	29	positive	positive	ADJ
fnp-3317	92	30	charge	charge	NOUN
fnp-3317	92	31	in	in	ADP
fnp-3317	92	32	the	the	DET
fnp-3317	92	33	microtubule	microtubule	NOUN
fnp-3317	92	34	binding	bind	VERB
fnp-3317	92	35	domain	domain	NOUN
fnp-3317	92	36	.	.	PUNCT
fnp-3317	93	1	these	these	DET
fnp-3317	93	2	findings	finding	NOUN
fnp-3317	93	3	are	be	AUX
fnp-3317	93	4	promising	promise	VERB
fnp-3317	93	5	because	because	SCONJ
fnp-3317	93	6	they	they	PRON
fnp-3317	93	7	give	give	VERB
fnp-3317	93	8	us	we	PRON
fnp-3317	93	9	the	the	DET
fnp-3317	93	10	most	most	ADV
fnp-3317	93	11	comprehensive	comprehensive	ADJ
fnp-3317	93	12	picture	picture	NOUN
fnp-3317	93	13	of	of	ADP
fnp-3317	93	14	tau	tau	PROPN
fnp-3317	93	15	secondary	secondary	ADJ
fnp-3317	93	16	structure	structure	NOUN
fnp-3317	93	17	and	and	CCONJ
fnp-3317	93	18	provide	provide	VERB
fnp-3317	93	19	a	a	DET
fnp-3317	93	20	pathway	pathway	NOUN
fnp-3317	93	21	towards	towards	ADP
fnp-3317	93	22	continuing	continue	VERB
fnp-3317	93	23	to	to	PART
fnp-3317	93	24	advance	advance	VERB
fnp-3317	93	25	the	the	DET
fnp-3317	93	26	biomarkers	biomarker	NOUN
fnp-3317	93	27	that	that	PRON
fnp-3317	93	28	are	be	AUX
fnp-3317	93	29	rapidly	rapidly	ADV
fnp-3317	93	30	evolving	evolve	VERB
fnp-3317	93	31	and	and	CCONJ
fnp-3317	93	32	identify	identify	VERB
fnp-3317	93	33	the	the	DET
fnp-3317	93	34	critical	critical	ADJ
fnp-3317	93	35	modifications	modification	NOUN
fnp-3317	93	36	that	that	PRON
fnp-3317	93	37	are	be	AUX
fnp-3317	93	38	responsible	responsible	ADJ
fnp-3317	93	39	for	for	ADP
fnp-3317	93	40	the	the	DET
fnp-3317	93	41	pathogenicity	pathogenicity	NOUN
fnp-3317	93	42	of	of	ADP
fnp-3317	93	43	tau	tau	PROPN
fnp-3317	93	44	paving	pave	VERB
fnp-3317	93	45	the	the	DET
fnp-3317	93	46	way	way	NOUN
fnp-3317	93	47	towards	towards	ADP
fnp-3317	93	48	new	new	ADJ
fnp-3317	93	49	therapeutics	therapeutic	NOUN
fnp-3317	93	50	.	.	PUNCT
fnp-3317	94	1	5	5	X
fnp-3317	94	2	.	.	X
fnp-3317	94	3	plasma	plasma	NOUN
fnp-3317	94	4	biomarkers	biomarker	NOUN
fnp-3317	94	5	for	for	ADP
fnp-3317	94	6	alzheimer	alzheimer	PROPN
fnp-3317	94	7	disease	disease	NOUN
fnp-3317	94	8	obtaining	obtain	VERB
fnp-3317	94	9	a	a	DET
fnp-3317	94	10	definitive	definitive	ADJ
fnp-3317	94	11	diagnosis	diagnosis	NOUN
fnp-3317	94	12	of	of	ADP
fnp-3317	94	13	a	a	DET
fnp-3317	94	14	neurodegenerative	neurodegenerative	ADJ
fnp-3317	94	15	disease	disease	NOUN
fnp-3317	94	16	continues	continue	VERB
fnp-3317	94	17	to	to	PART
fnp-3317	94	18	require	require	VERB
fnp-3317	94	19	an	an	DET
fnp-3317	94	20	autopsy	autopsy	NOUN
fnp-3317	94	21	,	,	PUNCT
fnp-3317	94	22	the	the	DET
fnp-3317	94	23	perennial	perennial	ADJ
fnp-3317	94	24	gold	gold	NOUN
fnp-3317	94	25	standard	standard	NOUN
fnp-3317	94	26	,	,	PUNCT
fnp-3317	94	27	but	but	CCONJ
fnp-3317	94	28	continued	continued	ADJ
fnp-3317	94	29	advances	advance	NOUN
fnp-3317	94	30	in	in	ADP
fnp-3317	94	31	blood	blood	NOUN
fnp-3317	94	32	-	-	PUNCT
fnp-3317	94	33	based	base	VERB
fnp-3317	94	34	biomarkers	biomarker	NOUN
fnp-3317	94	35	are	be	AUX
fnp-3317	94	36	continuing	continue	VERB
fnp-3317	94	37	to	to	PART
fnp-3317	94	38	challenge	challenge	VERB
fnp-3317	94	39	this	this	PRON
fnp-3317	94	40	and	and	CCONJ
fnp-3317	94	41	offer	offer	VERB
fnp-3317	94	42	a	a	DET
fnp-3317	94	43	low	low	ADJ
fnp-3317	94	44	-	-	PUNCT
fnp-3317	94	45	cost	cost	NOUN
fnp-3317	94	46	,	,	PUNCT
fnp-3317	94	47	convenient	convenient	ADJ
fnp-3317	94	48	alternative	alternative	NOUN
fnp-3317	94	49	.	.	PUNCT
fnp-3317	95	1	over	over	ADP
fnp-3317	95	2	the	the	DET
fnp-3317	95	3	past	past	ADJ
fnp-3317	95	4	decade	decade	NOUN
fnp-3317	95	5	,	,	PUNCT
fnp-3317	95	6	substantial	substantial	ADJ
fnp-3317	95	7	progress	progress	NOUN
fnp-3317	95	8	has	have	AUX
fnp-3317	95	9	been	be	AUX
fnp-3317	95	10	made	make	VERB
fnp-3317	95	11	in	in	ADP
fnp-3317	95	12	our	our	PRON
fnp-3317	95	13	ability	ability	NOUN
fnp-3317	95	14	to	to	PART
fnp-3317	95	15	assess	assess	VERB
fnp-3317	95	16	molecular	molecular	ADJ
fnp-3317	95	17	changes	change	NOUN
fnp-3317	95	18	in	in	ADP
fnp-3317	95	19	the	the	DET
fnp-3317	95	20	central	central	ADJ
fnp-3317	95	21	nervous	nervous	ADJ
fnp-3317	95	22	system	system	NOUN
fnp-3317	95	23	using	use	VERB
fnp-3317	95	24	non	non	ADJ
fnp-3317	95	25	-	-	ADJ
fnp-3317	95	26	invasive	invasive	ADJ
fnp-3317	95	27	amyloid	amyloid	NOUN
fnp-3317	95	28	positron	positron	NOUN
fnp-3317	95	29	emission	emission	NOUN
fnp-3317	95	30	tomography	tomography	NOUN
fnp-3317	95	31	(	(	PUNCT
fnp-3317	95	32	pet	pet	NOUN
fnp-3317	95	33	)	)	PUNCT
fnp-3317	95	34	scans	scan	NOUN
fnp-3317	95	35	and	and	CCONJ
fnp-3317	95	36	cerebrospinal	cerebrospinal	ADJ
fnp-3317	95	37	fluid	fluid	NOUN
fnp-3317	95	38	(	(	PUNCT
fnp-3317	95	39	csf	csf	NOUN
fnp-3317	95	40	)	)	PUNCT
fnp-3317	95	41	markers	marker	NOUN
fnp-3317	95	42	.	.	PUNCT
fnp-3317	96	1	yet	yet	CCONJ
fnp-3317	96	2	these	these	DET
fnp-3317	96	3	modalities	modality	NOUN
fnp-3317	96	4	are	be	AUX
fnp-3317	96	5	expensive	expensive	ADJ
fnp-3317	96	6	,	,	PUNCT
fnp-3317	96	7	inconvenient	inconvenient	ADJ
fnp-3317	96	8	and	and	CCONJ
fnp-3317	96	9	come	come	VERB
fnp-3317	96	10	with	with	ADP
fnp-3317	96	11	a	a	DET
fnp-3317	96	12	mild	mild	ADJ
fnp-3317	96	13	degree	degree	NOUN
fnp-3317	96	14	of	of	ADP
fnp-3317	96	15	risk	risk	NOUN
fnp-3317	96	16	.	.	PUNCT
fnp-3317	97	1	the	the	DET
fnp-3317	97	2	long	long	ADV
fnp-3317	97	3	-	-	PUNCT
fnp-3317	97	4	sought	seek	VERB
fnp-3317	97	5	development	development	NOUN
fnp-3317	97	6	of	of	ADP
fnp-3317	97	7	a	a	DET
fnp-3317	97	8	blood	blood	NOUN
fnp-3317	97	9	-	-	PUNCT
fnp-3317	97	10	based	base	VERB
fnp-3317	97	11	biomarker	biomarker	NOUN
fnp-3317	97	12	for	for	ADP
fnp-3317	97	13	alzheimer	alzheimer	PROPN
fnp-3317	97	14	disease	disease	NOUN
fnp-3317	97	15	(	(	PUNCT
fnp-3317	97	16	ad	ad	NOUN
fnp-3317	97	17	)	)	PUNCT
fnp-3317	97	18	,	,	PUNCT
fnp-3317	97	19	had	have	AUX
fnp-3317	97	20	been	be	AUX
fnp-3317	97	21	considered	consider	VERB
fnp-3317	97	22	unrealistic	unrealistic	ADJ
fnp-3317	97	23	because	because	SCONJ
fnp-3317	97	24	the	the	DET
fnp-3317	97	25	levels	level	NOUN
fnp-3317	97	26	of	of	ADP
fnp-3317	97	27	brain	brain	NOUN
fnp-3317	97	28	proteins	protein	NOUN
fnp-3317	97	29	in	in	ADP
fnp-3317	97	30	the	the	DET
fnp-3317	97	31	blood	blood	NOUN
fnp-3317	97	32	had	have	AUX
fnp-3317	97	33	been	be	AUX
fnp-3317	97	34	thought	think	VERB
fnp-3317	97	35	to	to	PART
fnp-3317	97	36	be	be	AUX
fnp-3317	97	37	simply	simply	ADV
fnp-3317	97	38	too	too	ADV
fnp-3317	97	39	low	low	ADJ
fnp-3317	97	40	to	to	PART
fnp-3317	97	41	be	be	AUX
fnp-3317	97	42	reliably	reliably	ADV
fnp-3317	97	43	and	and	CCONJ
fnp-3317	97	44	reproducibly	reproducibly	ADV
fnp-3317	97	45	detected	detect	VERB
fnp-3317	97	46	.	.	PUNCT
fnp-3317	98	1	further	far	ADV
fnp-3317	98	2	,	,	PUNCT
fnp-3317	98	3	there	there	PRON
fnp-3317	98	4	was	be	VERB
fnp-3317	98	5	concern	concern	NOUN
fnp-3317	98	6	that	that	SCONJ
fnp-3317	98	7	the	the	DET
fnp-3317	98	8	extent	extent	NOUN
fnp-3317	98	9	to	to	PART
fnp-3317	98	10	which	which	PRON
fnp-3317	98	11	blood	blood	NOUN
fnp-3317	98	12	levels	level	NOUN
fnp-3317	98	13	of	of	ADP
fnp-3317	98	14	various	various	ADJ
fnp-3317	98	15	factors	factor	NOUN
fnp-3317	98	16	reflect	reflect	VERB
fnp-3317	98	17	ongoing	ongoing	ADJ
fnp-3317	98	18	disease	disease	NOUN
fnp-3317	98	19	processes	process	NOUN
fnp-3317	98	20	might	might	AUX
fnp-3317	98	21	be	be	AUX
fnp-3317	98	22	too	too	ADV
fnp-3317	98	23	disconnected	disconnected	ADJ
fnp-3317	98	24	or	or	CCONJ
fnp-3317	98	25	tangential	tangential	ADJ
fnp-3317	98	26	to	to	PART
fnp-3317	98	27	be	be	AUX
fnp-3317	98	28	clinically	clinically	ADV
fnp-3317	98	29	useful	useful	ADJ
fnp-3317	98	30	.	.	PUNCT
fnp-3317	99	1	so	so	ADV
fnp-3317	99	2	,	,	PUNCT
fnp-3317	99	3	it	it	PRON
fnp-3317	99	4	comes	come	VERB
fnp-3317	99	5	as	as	ADP
fnp-3317	99	6	no	no	DET
fnp-3317	99	7	surprise	surprise	NOUN
fnp-3317	99	8	that	that	SCONJ
fnp-3317	99	9	the	the	DET
fnp-3317	99	10	research	research	NOUN
fnp-3317	99	11	community	community	NOUN
fnp-3317	99	12	has	have	AUX
fnp-3317	99	13	been	be	AUX
fnp-3317	99	14	stunned	stun	VERB
fnp-3317	99	15	by	by	ADP
fnp-3317	99	16	the	the	DET
fnp-3317	99	17	rapid	rapid	ADJ
fnp-3317	99	18	progress	progress	NOUN
fnp-3317	99	19	in	in	ADP
fnp-3317	99	20	blood	blood	NOUN
fnp-3317	99	21	-	-	PUNCT
fnp-3317	99	22	based	base	VERB
fnp-3317	99	23	biomarkers	biomarker	NOUN
fnp-3317	99	24	in	in	ADP
fnp-3317	99	25	neurodegeneration	neurodegeneration	NOUN
fnp-3317	99	26	.	.	PUNCT
fnp-3317	100	1	this	this	DET
fnp-3317	100	2	year	year	NOUN
fnp-3317	100	3	a	a	DET
fnp-3317	100	4	milestone	milestone	NOUN
fnp-3317	100	5	was	be	AUX
fnp-3317	100	6	achieved	achieve	VERB
fnp-3317	100	7	,	,	PUNCT
fnp-3317	100	8	with	with	ADP
fnp-3317	100	9	the	the	DET
fnp-3317	100	10	“	"	PUNCT
fnp-3317	100	11	precivityad	precivityad	PROPN
fnp-3317	100	12	™	™	NOUN
fnp-3317	100	13	”	"	PUNCT
fnp-3317	100	14	mass	mass	ADJ
fnp-3317	100	15	-	-	PUNCT
fnp-3317	100	16	spec	spec	NOUN
fnp-3317	100	17	amyloid	amyloid	NOUN
fnp-3317	100	18	-	-	PUNCT
fnp-3317	100	19	β	β	X
fnp-3317	100	20	assay	assay	NOUN
fnp-3317	100	21	,	,	PUNCT
fnp-3317	100	22	which	which	PRON
fnp-3317	100	23	was	be	AUX
fnp-3317	100	24	developed	develop	VERB
fnp-3317	100	25	at	at	ADP
fnp-3317	100	26	washington	washington	PROPN
fnp-3317	100	27	university	university	PROPN
fnp-3317	100	28	saint	saint	NOUN
fnp-3317	100	29	louis	louis	PROPN
fnp-3317	100	30	in	in	ADP
fnp-3317	100	31	the	the	DET
fnp-3317	100	32	laboratory	laboratory	NOUN
fnp-3317	100	33	directed	direct	VERB
fnp-3317	100	34	by	by	ADP
fnp-3317	100	35	dr	dr	PROPN
fnp-3317	100	36	.	.	PROPN
fnp-3317	100	37	randall	randall	PROPN
fnp-3317	100	38	bateman	bateman	PROPN
fnp-3317	100	39	,	,	PUNCT
fnp-3317	100	40	receiving	receive	VERB
fnp-3317	100	41	approval	approval	NOUN
fnp-3317	100	42	under	under	ADP
fnp-3317	100	43	the	the	DET
fnp-3317	100	44	clinical	clinical	ADJ
fnp-3317	100	45	laboratory	laboratory	NOUN
fnp-3317	100	46	improvement	improvement	NOUN
fnp-3317	100	47	amendments	amendment	NOUN
fnp-3317	100	48	(	(	PUNCT
fnp-3317	100	49	clia	clia	PROPN
fnp-3317	100	50	)	)	PUNCT
fnp-3317	100	51	as	as	ADV
fnp-3317	100	52	well	well	ADV
fnp-3317	100	53	as	as	ADP
fnp-3317	100	54	an	an	DET
fnp-3317	100	55	fda	fda	PROPN
fnp-3317	100	56	breakthrough	breakthrough	NOUN
fnp-3317	100	57	designation	designation	NOUN
fnp-3317	100	58	.	.	PUNCT
fnp-3317	101	1	however	however	ADV
fnp-3317	101	2	,	,	PUNCT
fnp-3317	101	3	this	this	PRON
fnp-3317	101	4	is	be	AUX
fnp-3317	101	5	only	only	ADV
fnp-3317	101	6	half	half	NOUN
fnp-3317	101	7	of	of	ADP
fnp-3317	101	8	the	the	DET
fnp-3317	101	9	story	story	NOUN
fnp-3317	101	10	.	.	PUNCT
fnp-3317	102	1	the	the	DET
fnp-3317	102	2	other	other	ADJ
fnp-3317	102	3	essential	essential	ADJ
fnp-3317	102	4	neuropathological	neuropathological	ADJ
fnp-3317	102	5	hallmark	hallmark	NOUN
fnp-3317	102	6	of	of	ADP
fnp-3317	102	7	ad	ad	NOUN
fnp-3317	102	8	,	,	PUNCT
fnp-3317	102	9	the	the	DET
fnp-3317	102	10	neurofibrillary	neurofibrillary	ADJ
fnp-3317	102	11	tangle	tangle	NOUN
fnp-3317	102	12	composed	compose	VERB
fnp-3317	102	13	of	of	ADP
fnp-3317	102	14	abnormal	abnormal	ADJ
fnp-3317	102	15	tau	tau	NOUN
fnp-3317	102	16	,	,	PUNCT
fnp-3317	102	17	is	be	AUX
fnp-3317	102	18	also	also	ADV
fnp-3317	102	19	required	require	VERB
fnp-3317	102	20	for	for	ADP
fnp-3317	102	21	a	a	DET
fnp-3317	102	22	diagnosis	diagnosis	NOUN
fnp-3317	102	23	.	.	PUNCT
fnp-3317	103	1	remarkably	remarkably	ADV
fnp-3317	103	2	,	,	PUNCT
fnp-3317	103	3	similar	similar	ADJ
fnp-3317	103	4	rapid	rapid	ADJ
fnp-3317	103	5	progress	progress	NOUN
fnp-3317	103	6	is	be	AUX
fnp-3317	103	7	being	be	AUX
fnp-3317	103	8	made	make	VERB
fnp-3317	103	9	on	on	ADP
fnp-3317	103	10	this	this	DET
fnp-3317	103	11	front	front	NOUN
fnp-3317	103	12	with	with	ADP
fnp-3317	103	13	a	a	DET
fnp-3317	103	14	series	series	NOUN
fnp-3317	103	15	of	of	ADP
fnp-3317	103	16	groundbreaking	groundbreake	VERB
fnp-3317	103	17	studies	study	NOUN
fnp-3317	103	18	that	that	PRON
fnp-3317	103	19	were	be	AUX
fnp-3317	103	20	published	publish	VERB
fnp-3317	103	21	over	over	ADP
fnp-3317	103	22	that	that	DET
fnp-3317	103	23	past	past	ADJ
fnp-3317	103	24	year	year	NOUN
fnp-3317	103	25	,	,	PUNCT
fnp-3317	103	26	continuing	continue	VERB
fnp-3317	103	27	the	the	DET
fnp-3317	103	28	momentum	momentum	NOUN
fnp-3317	103	29	.	.	PUNCT
fnp-3317	104	1	in	in	ADP
fnp-3317	104	2	previous	previous	ADJ
fnp-3317	104	3	years	year	NOUN
fnp-3317	104	4	,	,	PUNCT
fnp-3317	104	5	the	the	DET
fnp-3317	104	6	first	first	ADJ
fnp-3317	104	7	papers	paper	NOUN
fnp-3317	104	8	emerged	emerge	VERB
fnp-3317	104	9	describing	describe	VERB
fnp-3317	104	10	highly	highly	ADV
fnp-3317	104	11	sensitive	sensitive	ADJ
fnp-3317	104	12	immunoassays	immunoassay	NOUN
fnp-3317	104	13	identifying	identify	VERB
fnp-3317	104	14	p	p	PROPN
fnp-3317	104	15	-	-	PUNCT
fnp-3317	104	16	tau	tau	NOUN
fnp-3317	104	17	phosphorylated	phosphorylate	VERB
fnp-3317	104	18	at	at	ADP
fnp-3317	104	19	threonines	threonine	NOUN
fnp-3317	104	20	181	181	NUM
fnp-3317	104	21	or	or	CCONJ
fnp-3317	104	22	217	217	NUM
fnp-3317	104	23	as	as	ADP
fnp-3317	104	24	early	early	ADJ
fnp-3317	104	25	promising	promising	ADJ
fnp-3317	104	26	biomarkers	biomarker	NOUN
fnp-3317	104	27	.	.	PUNCT
fnp-3317	105	1	in	in	ADP
fnp-3317	105	2	2020	2020	NUM
fnp-3317	105	3	,	,	PUNCT
fnp-3317	105	4	phospho	phospho	ADJ
fnp-3317	105	5	-	-	ADJ
fnp-3317	105	6	threonine	threonine	ADJ
fnp-3317	105	7	231	231	NUM
fnp-3317	105	8	(	(	PUNCT
fnp-3317	105	9	p	p	NOUN
fnp-3317	105	10	-	-	PUNCT
fnp-3317	105	11	tau231	tau231	NOUN
fnp-3317	105	12	)	)	PUNCT
fnp-3317	105	13	was	be	AUX
fnp-3317	105	14	reported	report	VERB
fnp-3317	105	15	to	to	PART
fnp-3317	105	16	be	be	AUX
fnp-3317	105	17	an	an	DET
fnp-3317	105	18	excellent	excellent	ADJ
fnp-3317	105	19	early	early	ADJ
fnp-3317	105	20	marker	marker	NOUN
fnp-3317	105	21	for	for	ADP
fnp-3317	105	22	tau	tau	PROPN
fnp-3317	105	23	pathology	pathology	NOUN
fnp-3317	105	24	in	in	ADP
fnp-3317	105	25	csf	csf	PROPN
fnp-3317	105	26	(	(	PUNCT
fnp-3317	105	27	suárez	suárez	NOUN
fnp-3317	105	28	-	-	PUNCT
fnp-3317	105	29	calvet	calvet	NOUN
fnp-3317	105	30	et	et	PROPN
fnp-3317	105	31	al	al	PROPN
fnp-3317	105	32	.	.	PROPN
fnp-3317	105	33	,	,	PUNCT
fnp-3317	105	34	2020	2020	NUM
fnp-3317	105	35	)	)	PUNCT
fnp-3317	105	36	.	.	PUNCT
fnp-3317	106	1	this	this	PRON
fnp-3317	106	2	was	be	AUX
fnp-3317	106	3	followed	follow	VERB
fnp-3317	106	4	up	up	ADP
fnp-3317	106	5	with	with	ADP
fnp-3317	106	6	results	result	NOUN
fnp-3317	106	7	from	from	ADP
fnp-3317	106	8	a	a	DET
fnp-3317	106	9	study	study	NOUN
fnp-3317	106	10	using	use	VERB
fnp-3317	106	11	an	an	DET
fnp-3317	106	12	ultrasensitive	ultrasensitive	ADJ
fnp-3317	106	13	single	single	ADJ
fnp-3317	106	14	molecule	molecule	NOUN
fnp-3317	106	15	array	array	NOUN
fnp-3317	106	16	(	(	PUNCT
fnp-3317	106	17	simoa	simoa	PROPN
fnp-3317	106	18	)	)	PUNCT
fnp-3317	106	19	for	for	ADP
fnp-3317	106	20	the	the	DET
fnp-3317	106	21	quantification	quantification	NOUN
fnp-3317	106	22	of	of	ADP
fnp-3317	106	23	p	p	PROPN
fnp-3317	106	24	-	-	PUNCT
fnp-3317	106	25	tau231	tau231	NOUN
fnp-3317	106	26	in	in	ADP
fnp-3317	106	27	blood	blood	NOUN
fnp-3317	106	28	plasma	plasma	NOUN
fnp-3317	106	29	(	(	PUNCT
fnp-3317	106	30	ashton	ashton	PROPN
fnp-3317	106	31	et	et	PROPN
fnp-3317	106	32	al	al	PROPN
fnp-3317	106	33	.	.	PROPN
fnp-3317	106	34	,	,	PUNCT
fnp-3317	106	35	2021	2021	NUM
fnp-3317	106	36	)	)	PUNCT
fnp-3317	106	37	.	.	PUNCT
fnp-3317	107	1	the	the	DET
fnp-3317	107	2	study	study	NOUN
fnp-3317	107	3	included	include	VERB
fnp-3317	107	4	a	a	DET
fnp-3317	107	5	total	total	NOUN
fnp-3317	107	6	of	of	ADP
fnp-3317	107	7	588	588	NUM
fnp-3317	107	8	subjects	subject	NOUN
fnp-3317	107	9	and	and	CCONJ
fnp-3317	107	10	successfully	successfully	ADV
fnp-3317	107	11	differentiated	differentiate	VERB
fnp-3317	107	12	ad	ad	NOUN
fnp-3317	107	13	from	from	ADP
fnp-3317	107	14	amyloid	amyloid	NOUN
fnp-3317	107	15	-	-	PUNCT
fnp-3317	107	16	β	β	X
fnp-3317	107	17	negative	negative	ADJ
fnp-3317	107	18	cognitively	cognitively	ADV
fnp-3317	107	19	normal	normal	ADJ
fnp-3317	107	20	individuals	individual	NOUN
fnp-3317	107	21	.	.	PUNCT
fnp-3317	108	1	plasma	plasma	NOUN
fnp-3317	108	2	p	p	PROPN
fnp-3317	108	3	-	-	PUNCT
fnp-3317	108	4	tau231	tau231	PROPN
fnp-3317	108	5	also	also	ADV
fnp-3317	108	6	differentiated	differentiate	VERB
fnp-3317	108	7	ad	ad	NOUN
fnp-3317	108	8	patients	patient	NOUN
fnp-3317	108	9	from	from	ADP
fnp-3317	108	10	non	non	ADJ
fnp-3317	108	11	-	-	ADJ
fnp-3317	108	12	ad	ad	ADJ
fnp-3317	108	13	neurodegenerative	neurodegenerative	ADJ
fnp-3317	108	14	disorders	disorder	NOUN
fnp-3317	108	15	and	and	CCONJ
fnp-3317	108	16	amyloid	amyloid	NOUN
fnp-3317	108	17	-	-	PUNCT
fnp-3317	108	18	β	β	X
fnp-3317	108	19	negative	negative	ADJ
fnp-3317	108	20	mci	mci	PROPN
fnp-3317	108	21	patients	patient	NOUN
fnp-3317	108	22	.	.	PUNCT
fnp-3317	109	1	in	in	ADP
fnp-3317	109	2	samples	sample	NOUN
fnp-3317	109	3	taken	take	VERB
fnp-3317	109	4	from	from	ADP
fnp-3317	109	5	patients	patient	NOUN
fnp-3317	109	6	with	with	ADP
fnp-3317	109	7	post	post	ADJ
fnp-3317	109	8	-	-	ADJ
fnp-3317	109	9	mortem	mortem	ADJ
fnp-3317	109	10	autopsy	autopsy	ADJ
fnp-3317	109	11	confirmation	confirmation	NOUN
fnp-3317	109	12	,	,	PUNCT
fnp-3317	109	13	plasma	plasma	NOUN
fnp-3317	109	14	p	p	PROPN
fnp-3317	109	15	-	-	PUNCT
fnp-3317	109	16	tau231	tau231	PROPN
fnp-3317	109	17	was	be	AUX
fnp-3317	109	18	extremely	extremely	ADV
fnp-3317	109	19	accurate	accurate	ADJ
fnp-3317	109	20	in	in	ADP
fnp-3317	109	21	identifying	identify	VERB
fnp-3317	109	22	ad	ad	NOUN
fnp-3317	109	23	neuropathology	neuropathology	NOUN
fnp-3317	109	24	in	in	ADP
fnp-3317	109	25	comparison	comparison	NOUN
fnp-3317	109	26	to	to	ADP
fnp-3317	109	27	non	non	ADJ
fnp-3317	109	28	-	-	ADJ
fnp-3317	109	29	ad	ad	ADJ
fnp-3317	109	30	neurodegenerative	neurodegenerative	ADJ
fnp-3317	109	31	disorders	disorder	NOUN
fnp-3317	109	32	(	(	PUNCT
fnp-3317	109	33	auc	auc	NOUN
fnp-3317	109	34	=	=	NOUN
fnp-3317	109	35	0.99	0.99	NUM
fnp-3317	109	36	)	)	PUNCT
fnp-3317	109	37	.	.	PUNCT
fnp-3317	110	1	plasma	plasma	NOUN
fnp-3317	110	2	p	p	PROPN
fnp-3317	110	3	-	-	PUNCT
fnp-3317	110	4	tau231	tau231	PROPN
fnp-3317	110	5	was	be	AUX
fnp-3317	110	6	highly	highly	ADV
fnp-3317	110	7	correlated	correlate	VERB
fnp-3317	110	8	with	with	ADP
fnp-3317	110	9	other	other	ADJ
fnp-3317	110	10	ad	ad	NOUN
fnp-3317	110	11	biomarkers	biomarker	NOUN
fnp-3317	110	12	,	,	PUNCT
fnp-3317	110	13	i.e.	i.e.	X
fnp-3317	110	14	,	,	PUNCT
fnp-3317	110	15	csf	csf	ADJ
fnp-3317	110	16	p	p	PROPN
fnp-3317	110	17	-	-	PUNCT
fnp-3317	110	18	tau231	tau231	PROPN
fnp-3317	110	19	,	,	PUNCT
fnp-3317	110	20	tau	tau	PROPN
fnp-3317	110	21	pet	pet	NOUN
fnp-3317	110	22	(	(	PUNCT
fnp-3317	110	23	[	[	X
fnp-3317	110	24	18f]mk-6240	18f]mk-6240	NUM
fnp-3317	110	25	)	)	PUNCT
fnp-3317	110	26	and	and	CCONJ
fnp-3317	110	27	amyloid	amyloid	NOUN
fnp-3317	110	28	-	-	PUNCT
fnp-3317	110	29	β	β	X
fnp-3317	110	30	pet	pet	NOUN
fnp-3317	110	31	(	(	PUNCT
fnp-3317	110	32	[	[	NOUN
fnp-3317	110	33	18f]azd	18f]azd	NUM
fnp-3317	110	34	)	)	PUNCT
fnp-3317	110	35	.	.	PUNCT
fnp-3317	111	1	the	the	DET
fnp-3317	111	2	elevations	elevation	NOUN
fnp-3317	111	3	in	in	ADP
fnp-3317	111	4	p	p	PROPN
fnp-3317	111	5	-	-	PUNCT
fnp-3317	111	6	tau231	tau231	PROPN
fnp-3317	111	7	were	be	AUX
fnp-3317	111	8	a	a	DET
fnp-3317	111	9	very	very	ADV
fnp-3317	111	10	early	early	ADJ
fnp-3317	111	11	change	change	NOUN
fnp-3317	111	12	,	,	PUNCT
fnp-3317	111	13	preceding	precede	VERB
fnp-3317	111	14	amyloid	amyloid	NOUN
fnp-3317	111	15	-	-	PUNCT
fnp-3317	111	16	β	β	NOUN
fnp-3317	111	17	pet	pet	NOUN
fnp-3317	111	18	and	and	CCONJ
fnp-3317	111	19	plasma	plasma	VERB
fnp-3317	111	20	p	p	PROPN
fnp-3317	111	21	-	-	PUNCT
fnp-3317	111	22	tau181	tau181	PROPN
fnp-3317	111	23	.	.	PUNCT
fnp-3317	112	1	plasma	plasma	PROPN
fnp-3317	112	2	p	p	PROPN
fnp-3317	112	3	-	-	PUNCT
fnp-3317	112	4	tau231	tau231	PROPN
fnp-3317	112	5	had	have	VERB
fnp-3317	112	6	the	the	DET
fnp-3317	112	7	power	power	NOUN
fnp-3317	112	8	to	to	PART
fnp-3317	112	9	resolve	resolve	VERB
fnp-3317	112	10	even	even	ADV
fnp-3317	112	11	subtle	subtle	ADJ
fnp-3317	112	12	differences	difference	NOUN
fnp-3317	112	13	,	,	PUNCT
fnp-3317	112	14	differentiating	differentiate	VERB
fnp-3317	112	15	subjects	subject	NOUN
fnp-3317	112	16	across	across	ADP
fnp-3317	112	17	even	even	ADV
fnp-3317	112	18	early	early	ADJ
fnp-3317	112	19	braak	braak	NOUN
fnp-3317	112	20	stages	stage	NOUN
fnp-3317	112	21	.	.	PUNCT
fnp-3317	113	1	together	together	ADV
fnp-3317	113	2	,	,	PUNCT
fnp-3317	113	3	we	we	PRON
fnp-3317	113	4	are	be	AUX
fnp-3317	113	5	witnessing	witness	VERB
fnp-3317	113	6	impressive	impressive	ADJ
fnp-3317	113	7	progress	progress	NOUN
fnp-3317	113	8	in	in	ADP
fnp-3317	113	9	blood	blood	NOUN
fnp-3317	113	10	-	-	PUNCT
fnp-3317	113	11	based	base	VERB
fnp-3317	113	12	ad	ad	NOUN
fnp-3317	113	13	biomarkers	biomarker	NOUN
fnp-3317	113	14	with	with	ADP
fnp-3317	113	15	the	the	DET
fnp-3317	113	16	potential	potential	NOUN
fnp-3317	113	17	to	to	PART
fnp-3317	113	18	detect	detect	VERB
fnp-3317	113	19	the	the	DET
fnp-3317	113	20	earliest	early	ADJ
fnp-3317	113	21	disease	disease	NOUN
fnp-3317	113	22	stages	stage	NOUN
fnp-3317	113	23	,	,	PUNCT
fnp-3317	113	24	prior	prior	ADV
fnp-3317	113	25	to	to	ADP
fnp-3317	113	26	significant	significant	ADJ
fnp-3317	113	27	irreversible	irreversible	ADJ
fnp-3317	113	28	brain	brain	NOUN
fnp-3317	113	29	destruction	destruction	NOUN
fnp-3317	113	30	,	,	PUNCT
fnp-3317	113	31	and	and	CCONJ
fnp-3317	113	32	enable	enable	VERB
fnp-3317	113	33	the	the	DET
fnp-3317	113	34	next	next	ADJ
fnp-3317	113	35	generation	generation	NOUN
fnp-3317	113	36	of	of	ADP
fnp-3317	113	37	clinical	clinical	ADJ
fnp-3317	113	38	trials	trial	NOUN
fnp-3317	113	39	.	.	PUNCT
fnp-3317	114	1	6	6	X
fnp-3317	114	2	.	.	X
fnp-3317	114	3	cryo	cryo	NOUN
fnp-3317	114	4	-	-	PUNCT
fnp-3317	114	5	electron	electron	NOUN
fnp-3317	114	6	microscopy	microscopy	NOUN
fnp-3317	114	7	:	:	PUNCT
fnp-3317	114	8	ultrahigh	ultrahigh	ADJ
fnp-3317	114	9	resolution	resolution	NOUN
fnp-3317	114	10	structure	structure	NOUN
fnp-3317	114	11	of	of	ADP
fnp-3317	114	12	tau	tau	PROPN
fnp-3317	114	13	in	in	ADP
fnp-3317	114	14	corticobasal	corticobasal	NOUN
fnp-3317	114	15	degeneration	degeneration	NOUN
fnp-3317	114	16	in	in	ADP
fnp-3317	114	17	2017	2017	NUM
fnp-3317	114	18	,	,	PUNCT
fnp-3317	114	19	the	the	DET
fnp-3317	114	20	nobel	nobel	PROPN
fnp-3317	114	21	prize	prize	PROPN
fnp-3317	114	22	in	in	ADP
fnp-3317	114	23	chemistry	chemistry	NOUN
fnp-3317	114	24	was	be	AUX
fnp-3317	114	25	awarded	award	VERB
fnp-3317	114	26	to	to	ADP
fnp-3317	114	27	jacques	jacques	PROPN
fnp-3317	114	28	dubochet	dubochet	PROPN
fnp-3317	114	29	,	,	PUNCT
fnp-3317	114	30	joachim	joachim	PROPN
fnp-3317	114	31	frank	frank	PROPN
fnp-3317	114	32	and	and	CCONJ
fnp-3317	114	33	richard	richard	PROPN
fnp-3317	114	34	henderson	henderson	PROPN
fnp-3317	114	35	for	for	ADP
fnp-3317	114	36	cryo	cryo	NOUN
fnp-3317	114	37	-	-	PUNCT
fnp-3317	114	38	electron	electron	NOUN
fnp-3317	114	39	microscopy	microscopy	NOUN
fnp-3317	114	40	(	(	PUNCT
fnp-3317	114	41	cryo	cryo	NOUN
fnp-3317	114	42	-	-	PUNCT
fnp-3317	114	43	em	em	PROPN
fnp-3317	114	44	)	)	PUNCT
fnp-3317	114	45	.	.	PUNCT
fnp-3317	115	1	the	the	DET
fnp-3317	115	2	approach	approach	NOUN
fnp-3317	115	3	,	,	PUNCT
fnp-3317	115	4	which	which	PRON
fnp-3317	115	5	involves	involve	VERB
fnp-3317	115	6	cooling	cool	VERB
fnp-3317	115	7	samples	sample	NOUN
fnp-3317	115	8	to	to	ADP
fnp-3317	115	9	cryogenic	cryogenic	ADJ
fnp-3317	115	10	temperatures	temperature	NOUN
fnp-3317	115	11	and	and	CCONJ
fnp-3317	115	12	embedding	embed	VERB
fnp-3317	115	13	them	they	PRON
fnp-3317	115	14	in	in	ADP
fnp-3317	115	15	an	an	DET
fnp-3317	115	16	environment	environment	NOUN
fnp-3317	115	17	of	of	ADP
fnp-3317	115	18	vitreous	vitreous	ADJ
fnp-3317	115	19	water	water	NOUN
fnp-3317	115	20	,	,	PUNCT
fnp-3317	115	21	has	have	AUX
fnp-3317	115	22	been	be	AUX
fnp-3317	115	23	in	in	ADP
fnp-3317	115	24	development	development	NOUN
fnp-3317	115	25	since	since	SCONJ
fnp-3317	115	26	the	the	DET
fnp-3317	115	27	1970s	1970	NOUN
fnp-3317	115	28	,	,	PUNCT
fnp-3317	115	29	but	but	CCONJ
fnp-3317	115	30	recent	recent	ADJ
fnp-3317	115	31	technical	technical	ADJ
fnp-3317	115	32	advances	advance	NOUN
fnp-3317	115	33	in	in	ADP
fnp-3317	115	34	detectors	detector	NOUN
fnp-3317	115	35	and	and	CCONJ
fnp-3317	115	36	software	software	NOUN
fnp-3317	115	37	algorithms	algorithm	NOUN
fnp-3317	115	38	have	have	AUX
fnp-3317	115	39	enabled	enable	VERB
fnp-3317	115	40	solving	solve	VERB
fnp-3317	115	41	molecular	molecular	ADJ
fnp-3317	115	42	structures	structure	NOUN
fnp-3317	115	43	at	at	ADP
fnp-3317	115	44	near	near	ADJ
fnp-3317	115	45	-	-	PUNCT
fnp-3317	115	46	atomic	atomic	ADJ
fnp-3317	115	47	resolution	resolution	NOUN
fnp-3317	115	48	.	.	PUNCT
fnp-3317	116	1	the	the	DET
fnp-3317	116	2	power	power	NOUN
fnp-3317	116	3	of	of	ADP
fnp-3317	116	4	cryo	cryo	NOUN
fnp-3317	116	5	-	-	PUNCT
fnp-3317	116	6	em	em	PRON
fnp-3317	116	7	was	be	AUX
fnp-3317	116	8	first	first	ADV
fnp-3317	116	9	demonstrated	demonstrate	VERB
fnp-3317	116	10	that	that	DET
fnp-3317	116	11	year	year	NOUN
fnp-3317	116	12	to	to	ADP
fnp-3317	116	13	the	the	DET
fnp-3317	116	14	neurodegenerative	neurodegenerative	ADJ
fnp-3317	116	15	disease	disease	NOUN
fnp-3317	116	16	research	research	NOUN
fnp-3317	116	17	community	community	NOUN
fnp-3317	116	18	when	when	SCONJ
fnp-3317	116	19	the	the	DET
fnp-3317	116	20	approach	approach	NOUN
fnp-3317	116	21	was	be	AUX
fnp-3317	116	22	applied	apply	VERB
fnp-3317	116	23	to	to	ADP
fnp-3317	116	24	paired	pair	VERB
fnp-3317	116	25	-	-	PUNCT
fnp-3317	116	26	helical	helical	ADJ
fnp-3317	116	27	filament	filament	NOUN
fnp-3317	116	28	tau	tau	NOUN
fnp-3317	116	29	fibrils	fibril	VERB
fnp-3317	116	30	in	in	ADP
fnp-3317	116	31	alzheimer	alzheimer	PROPN
fnp-3317	116	32	disease	disease	NOUN
fnp-3317	116	33	,	,	PUNCT
fnp-3317	116	34	illuminating	illuminate	VERB
fnp-3317	116	35	at	at	ADP
fnp-3317	116	36	near	near	ADP
fnp-3317	116	37	atomic	atomic	ADJ
fnp-3317	116	38	resolution	resolution	NOUN
fnp-3317	116	39	the	the	DET
fnp-3317	116	40	c	c	NOUN
fnp-3317	116	41	-	-	PUNCT
fnp-3317	116	42	shaped	shape	VERB
fnp-3317	116	43	conformation	conformation	NOUN
fnp-3317	116	44	of	of	ADP
fnp-3317	116	45	the	the	DET
fnp-3317	116	46	core	core	NOUN
fnp-3317	116	47	(	(	PUNCT
fnp-3317	116	48	fitzpatrick	fitzpatrick	PROPN
fnp-3317	116	49	et	et	PROPN
fnp-3317	116	50	al	al	PROPN
fnp-3317	116	51	.	.	PROPN
fnp-3317	116	52	,	,	PUNCT
fnp-3317	116	53	2017	2017	NUM
fnp-3317	116	54	)	)	PUNCT
fnp-3317	116	55	.	.	PUNCT
fnp-3317	117	1	this	this	DET
fnp-3317	117	2	report	report	NOUN
fnp-3317	117	3	was	be	AUX
fnp-3317	117	4	quickly	quickly	ADV
fnp-3317	117	5	followed	follow	VERB
fnp-3317	117	6	by	by	ADP
fnp-3317	117	7	the	the	DET
fnp-3317	117	8	solving	solving	NOUN
fnp-3317	117	9	of	of	ADP
fnp-3317	117	10	the	the	DET
fnp-3317	117	11	structure	structure	NOUN
fnp-3317	117	12	for	for	ADP
fnp-3317	117	13	the	the	DET
fnp-3317	117	14	j	j	PROPN
fnp-3317	117	15	-	-	PUNCT
fnp-3317	117	16	shaped	shape	VERB
fnp-3317	117	17	tau	tau	PROPN
fnp-3317	117	18	filament	filament	NOUN
fnp-3317	117	19	core	core	NOUN
fnp-3317	117	20	in	in	ADP
fnp-3317	117	21	pick	pick	NOUN
fnp-3317	117	22	disease	disease	NOUN
fnp-3317	117	23	which	which	PRON
fnp-3317	117	24	contains	contain	VERB
fnp-3317	117	25	additional	additional	ADJ
fnp-3317	117	26	residues	residue	NOUN
fnp-3317	117	27	making	make	VERB
fnp-3317	117	28	it	it	PRON
fnp-3317	117	29	slightly	slightly	ADV
fnp-3317	117	30	longer	long	ADV
fnp-3317	117	31	than	than	ADP
fnp-3317	117	32	in	in	ADP
fnp-3317	117	33	ad	ad	NOUN
fnp-3317	117	34	(	(	PUNCT
fnp-3317	117	35	falcon	falcon	PROPN
fnp-3317	117	36	et	et	PROPN
fnp-3317	117	37	al	al	PROPN
fnp-3317	117	38	.	.	PROPN
fnp-3317	117	39	,	,	PUNCT
fnp-3317	117	40	2018	2018	NUM
fnp-3317	117	41	)	)	PUNCT
fnp-3317	117	42	.	.	PUNCT
fnp-3317	118	1	next	next	ADJ
fnp-3317	118	2	came	come	VERB
fnp-3317	118	3	chronic	chronic	ADJ
fnp-3317	118	4	traumatic	traumatic	ADJ
fnp-3317	118	5	encephalopathy	encephalopathy	NOUN
fnp-3317	118	6	,	,	PUNCT
fnp-3317	118	7	which	which	PRON
fnp-3317	118	8	has	have	VERB
fnp-3317	118	9	a	a	DET
fnp-3317	118	10	similar	similar	ADJ
fnp-3317	118	11	c	c	NOUN
fnp-3317	118	12	-	-	PUNCT
fnp-3317	118	13	shape	shape	NOUN
fnp-3317	118	14	to	to	ADP
fnp-3317	118	15	that	that	PRON
fnp-3317	118	16	in	in	ADP
fnp-3317	118	17	alzheimer	alzheimer	PROPN
fnp-3317	118	18	disease	disease	PROPN
fnp-3317	118	19	(	(	PUNCT
fnp-3317	118	20	falcon	falcon	PROPN
fnp-3317	118	21	et	et	PROPN
fnp-3317	118	22	al	al	PROPN
fnp-3317	118	23	.	.	PROPN
fnp-3317	118	24	,	,	PUNCT
fnp-3317	118	25	2019	2019	NUM
fnp-3317	118	26	)	)	PUNCT
fnp-3317	118	27	.	.	PUNCT
fnp-3317	119	1	also	also	ADV
fnp-3317	119	2	described	describe	VERB
fnp-3317	119	3	was	be	AUX
fnp-3317	119	4	an	an	DET
fnp-3317	119	5	additional	additional	ADJ
fnp-3317	119	6	non	non	ADJ
fnp-3317	119	7	-	-	ADJ
fnp-3317	119	8	proteinaceous	proteinaceous	ADJ
fnp-3317	119	9	hydrophobic	hydrophobic	NOUN
fnp-3317	119	10	density	density	NOUN
fnp-3317	119	11	that	that	PRON
fnp-3317	119	12	has	have	VERB
fnp-3317	119	13	yet	yet	ADV
fnp-3317	119	14	to	to	PART
fnp-3317	119	15	be	be	AUX
fnp-3317	119	16	defined	define	VERB
fnp-3317	119	17	.	.	PUNCT
fnp-3317	120	1	these	these	DET
fnp-3317	120	2	findings	finding	NOUN
fnp-3317	120	3	support	support	VERB
fnp-3317	120	4	the	the	DET
fnp-3317	120	5	notion	notion	NOUN
fnp-3317	120	6	that	that	SCONJ
fnp-3317	120	7	there	there	PRON
fnp-3317	120	8	exists	exist	VERB
fnp-3317	120	9	a	a	DET
fnp-3317	120	10	spectrum	spectrum	NOUN
fnp-3317	120	11	of	of	ADP
fnp-3317	120	12	hitherto	hitherto	NOUN
fnp-3317	120	13	unrecognized	unrecognize	VERB
fnp-3317	120	14	tau	tau	PROPN
fnp-3317	120	15	structural	structural	ADJ
fnp-3317	120	16	features	feature	NOUN
fnp-3317	120	17	and	and	CCONJ
fnp-3317	120	18	conformations	conformation	NOUN
fnp-3317	120	19	,	,	PUNCT
fnp-3317	120	20	often	often	ADV
fnp-3317	120	21	termed	term	VERB
fnp-3317	120	22	“	"	PUNCT
fnp-3317	120	23	strains	strain	NOUN
fnp-3317	120	24	”	"	PUNCT
fnp-3317	120	25	in	in	ADP
fnp-3317	120	26	a	a	DET
fnp-3317	120	27	nod	nod	NOUN
fnp-3317	120	28	to	to	ADP
fnp-3317	120	29	the	the	DET
fnp-3317	120	30	prion	prion	NOUN
fnp-3317	120	31	literature	literature	NOUN
fnp-3317	120	32	that	that	PRON
fnp-3317	120	33	has	have	AUX
fnp-3317	120	34	informed	inform	VERB
fnp-3317	120	35	much	much	ADJ
fnp-3317	120	36	of	of	ADP
fnp-3317	120	37	the	the	DET
fnp-3317	120	38	research	research	NOUN
fnp-3317	120	39	on	on	ADP
fnp-3317	120	40	protein	protein	NOUN
fnp-3317	120	41	misfolding	misfolde	VERB
fnp-3317	120	42	,	,	PUNCT
fnp-3317	120	43	that	that	PRON
fnp-3317	120	44	may	may	AUX
fnp-3317	120	45	be	be	AUX
fnp-3317	120	46	distinct	distinct	ADJ
fnp-3317	120	47	in	in	ADP
fnp-3317	120	48	different	different	ADJ
fnp-3317	120	49	disease	disease	NOUN
fnp-3317	120	50	states	state	NOUN
fnp-3317	120	51	.	.	PUNCT
fnp-3317	121	1	now	now	ADV
fnp-3317	121	2	,	,	PUNCT
fnp-3317	121	3	we	we	PRON
fnp-3317	121	4	are	be	AUX
fnp-3317	121	5	continuing	continue	VERB
fnp-3317	121	6	to	to	PART
fnp-3317	121	7	see	see	VERB
fnp-3317	121	8	additional	additional	ADJ
fnp-3317	121	9	insights	insight	NOUN
fnp-3317	121	10	with	with	ADP
fnp-3317	121	11	two	two	NUM
fnp-3317	121	12	papers	paper	NOUN
fnp-3317	121	13	describing	describe	VERB
fnp-3317	121	14	the	the	DET
fnp-3317	121	15	structure	structure	NOUN
fnp-3317	121	16	of	of	ADP
fnp-3317	121	17	the	the	DET
fnp-3317	121	18	tau	tau	PROPN
fnp-3317	121	19	filament	filament	NOUN
fnp-3317	121	20	core	core	NOUN
fnp-3317	121	21	in	in	ADP
fnp-3317	121	22	corticobasal	corticobasal	NOUN
fnp-3317	121	23	degeneration	degeneration	NOUN
fnp-3317	121	24	as	as	ADV
fnp-3317	121	25	well	well	ADV
fnp-3317	121	26	as	as	ADP
fnp-3317	121	27	another	another	PRON
fnp-3317	121	28	which	which	PRON
fnp-3317	121	29	is	be	AUX
fnp-3317	121	30	the	the	DET
fnp-3317	121	31	first	first	ADJ
fnp-3317	121	32	cryo	cryo	NOUN
fnp-3317	121	33	-	-	PUNCT
fnp-3317	121	34	em	em	PRON
fnp-3317	121	35	structure	structure	NOUN
fnp-3317	121	36	of	of	ADP
fnp-3317	121	37	α	α	NOUN
fnp-3317	121	38	-	-	PUNCT
fnp-3317	121	39	synuclein	synuclein	NOUN
fnp-3317	121	40	(	(	PUNCT
fnp-3317	121	41	see	see	VERB
fnp-3317	121	42	next	next	ADJ
fnp-3317	121	43	section	section	NOUN
fnp-3317	121	44	)	)	PUNCT
fnp-3317	121	45	.	.	PUNCT
fnp-3317	122	1	in	in	ADP
fnp-3317	122	2	a	a	DET
fnp-3317	122	3	paper	paper	NOUN
fnp-3317	122	4	published	publish	VERB
fnp-3317	122	5	in	in	ADP
fnp-3317	122	6	cell	cell	NOUN
fnp-3317	122	7	in	in	ADP
fnp-3317	122	8	february	february	PROPN
fnp-3317	122	9	2020	2020	NUM
fnp-3317	122	10	,	,	PUNCT
fnp-3317	122	11	a	a	DET
fnp-3317	122	12	team	team	NOUN
fnp-3317	122	13	led	lead	VERB
fnp-3317	122	14	by	by	ADP
fnp-3317	122	15	anthony	anthony	PROPN
fnp-3317	122	16	fitzpatrick	fitzpatrick	PROPN
fnp-3317	122	17	at	at	ADP
fnp-3317	122	18	columbia	columbia	PROPN
fnp-3317	122	19	university	university	PROPN
fnp-3317	122	20	detailed	detail	VERB
fnp-3317	122	21	their	their	PRON
fnp-3317	122	22	study	study	NOUN
fnp-3317	122	23	showing	show	VERB
fnp-3317	122	24	the	the	DET
fnp-3317	122	25	cryo	cryo	NOUN
fnp-3317	122	26	-	-	PUNCT
fnp-3317	122	27	em	em	PRON
fnp-3317	122	28	structure	structure	NOUN
fnp-3317	122	29	of	of	ADP
fnp-3317	122	30	filaments	filament	NOUN
fnp-3317	122	31	from	from	ADP
fnp-3317	122	32	corticobasal	corticobasal	NOUN
fnp-3317	122	33	degeneration	degeneration	NOUN
fnp-3317	122	34	(	(	PUNCT
fnp-3317	122	35	arakhamia	arakhamia	NOUN
fnp-3317	122	36	et	et	PROPN
fnp-3317	122	37	al	al	PROPN
fnp-3317	122	38	.	.	PROPN
fnp-3317	122	39	,	,	PUNCT
fnp-3317	122	40	2020	2020	NUM
fnp-3317	122	41	)	)	PUNCT
fnp-3317	122	42	.	.	PUNCT
fnp-3317	123	1	in	in	ADP
fnp-3317	123	2	additional	additional	ADJ
fnp-3317	123	3	analyses	analysis	NOUN
fnp-3317	123	4	,	,	PUNCT
fnp-3317	123	5	they	they	PRON
fnp-3317	123	6	further	far	ADV
fnp-3317	123	7	integrated	integrate	VERB
fnp-3317	123	8	these	these	DET
fnp-3317	123	9	cryo	cryo	NOUN
fnp-3317	123	10	-	-	PUNCT
fnp-3317	123	11	em	em	PRON
fnp-3317	123	12	structures	structure	NOUN
fnp-3317	123	13	and	and	CCONJ
fnp-3317	123	14	those	those	PRON
fnp-3317	123	15	from	from	ADP
fnp-3317	123	16	ad	ad	NOUN
fnp-3317	123	17	with	with	ADP
fnp-3317	123	18	mass	mass	ADJ
fnp-3317	123	19	spectrometry	spectrometry	NOUN
fnp-3317	123	20	data	datum	NOUN
fnp-3317	123	21	to	to	PART
fnp-3317	123	22	localize	localize	VERB
fnp-3317	123	23	post	post	ADJ
fnp-3317	123	24	-	-	ADJ
fnp-3317	123	25	translational	translational	ADJ
fnp-3317	123	26	secondary	secondary	ADJ
fnp-3317	123	27	modifications	modification	NOUN
fnp-3317	123	28	.	.	PUNCT
fnp-3317	124	1	a	a	DET
fnp-3317	124	2	separate	separate	ADJ
fnp-3317	124	3	study	study	NOUN
fnp-3317	124	4	,	,	PUNCT
fnp-3317	124	5	published	publish	VERB
fnp-3317	124	6	in	in	ADP
fnp-3317	124	7	nature	nature	NOUN
fnp-3317	124	8	,	,	PUNCT
fnp-3317	124	9	led	lead	VERB
fnp-3317	124	10	by	by	ADP
fnp-3317	124	11	sjors	sjor	NOUN
fnp-3317	124	12	scheres	schere	NOUN
fnp-3317	124	13	and	and	CCONJ
fnp-3317	124	14	michel	michel	PROPN
fnp-3317	124	15	goedert	goedert	PROPN
fnp-3317	124	16	at	at	ADP
fnp-3317	124	17	the	the	DET
fnp-3317	124	18	mrc	mrc	NOUN
fnp-3317	124	19	laboratory	laboratory	NOUN
fnp-3317	124	20	of	of	ADP
fnp-3317	124	21	molecular	molecular	ADJ
fnp-3317	124	22	biology	biology	NOUN
fnp-3317	124	23	in	in	ADP
fnp-3317	124	24	cambridge	cambridge	PROPN
fnp-3317	124	25	,	,	PUNCT
fnp-3317	124	26	england	england	PROPN
fnp-3317	124	27	,	,	PUNCT
fnp-3317	124	28	u.k	u.k	PROPN
fnp-3317	124	29	.	.	PROPN
fnp-3317	124	30	(	(	PUNCT
fnp-3317	124	31	zhang	zhang	PROPN
fnp-3317	124	32	et	et	PROPN
fnp-3317	124	33	al	al	PROPN
fnp-3317	124	34	.	.	PROPN
fnp-3317	124	35	,	,	PUNCT
fnp-3317	124	36	2020	2020	NUM
fnp-3317	124	37	)	)	PUNCT
fnp-3317	124	38	.	.	PUNCT
fnp-3317	125	1	this	this	DET
fnp-3317	125	2	team	team	NOUN
fnp-3317	125	3	also	also	ADV
fnp-3317	125	4	showed	show	VERB
fnp-3317	125	5	a	a	DET
fnp-3317	125	6	similar	similar	ADJ
fnp-3317	125	7	structure	structure	NOUN
fnp-3317	125	8	in	in	ADP
fnp-3317	125	9	cbd	cbd	NOUN
fnp-3317	125	10	(	(	PUNCT
fnp-3317	125	11	figure	figure	NOUN
fnp-3317	125	12	4	4	NUM
fnp-3317	125	13	)	)	PUNCT
fnp-3317	125	14	.	.	PUNCT
fnp-3317	126	1	together	together	ADV
fnp-3317	126	2	,	,	PUNCT
fnp-3317	126	3	in	in	ADP
fnp-3317	126	4	addition	addition	NOUN
fnp-3317	126	5	to	to	ADP
fnp-3317	126	6	providing	provide	VERB
fnp-3317	126	7	a	a	DET
fnp-3317	126	8	validated	validate	VERB
fnp-3317	126	9	atomic	atomic	ADJ
fnp-3317	126	10	level	level	NOUN
fnp-3317	126	11	resolution	resolution	NOUN
fnp-3317	126	12	c	c	NOUN
fnp-3317	126	13	-	-	PUNCT
fnp-3317	126	14	shaped	shape	VERB
fnp-3317	126	15	structure	structure	NOUN
fnp-3317	126	16	of	of	ADP
fnp-3317	126	17	the	the	DET
fnp-3317	126	18	tau	tau	PROPN
fnp-3317	126	19	filament	filament	NOUN
fnp-3317	126	20	in	in	ADP
fnp-3317	126	21	cbd	cbd	PROPN
fnp-3317	126	22	,	,	PUNCT
fnp-3317	126	23	these	these	DET
fnp-3317	126	24	studies	study	NOUN
fnp-3317	126	25	both	both	PRON
fnp-3317	126	26	revealed	reveal	VERB
fnp-3317	126	27	a	a	DET
fnp-3317	126	28	density	density	NOUN
fnp-3317	126	29	buried	bury	VERB
fnp-3317	126	30	in	in	ADP
fnp-3317	126	31	the	the	DET
fnp-3317	126	32	structure	structure	NOUN
fnp-3317	126	33	that	that	PRON
fnp-3317	126	34	represents	represent	VERB
fnp-3317	126	35	a	a	DET
fnp-3317	126	36	molecule	molecule	NOUN
fnp-3317	126	37	of	of	ADP
fnp-3317	126	38	unknown	unknown	ADJ
fnp-3317	126	39	identity	identity	NOUN
fnp-3317	126	40	,	,	PUNCT
fnp-3317	126	41	akin	akin	ADJ
fnp-3317	126	42	to	to	ADP
fnp-3317	126	43	what	what	PRON
fnp-3317	126	44	was	be	AUX
fnp-3317	126	45	identified	identify	VERB
fnp-3317	126	46	in	in	ADP
fnp-3317	126	47	cte	cte	PROPN
fnp-3317	126	48	.	.	PUNCT
fnp-3317	127	1	the	the	DET
fnp-3317	127	2	fibrils	fibril	NOUN
fnp-3317	127	3	in	in	ADP
fnp-3317	127	4	cbd	cbd	NOUN
fnp-3317	127	5	are	be	AUX
fnp-3317	127	6	composed	compose	VERB
fnp-3317	127	7	entirely	entirely	ADV
fnp-3317	127	8	of	of	ADP
fnp-3317	127	9	tau	tau	PROPN
fnp-3317	127	10	with	with	ADP
fnp-3317	127	11	4	4	NUM
fnp-3317	127	12	microtubule	microtubule	NOUN
fnp-3317	127	13	binding	bind	VERB
fnp-3317	127	14	domain	domain	NOUN
fnp-3317	127	15	repeats	repeat	NOUN
fnp-3317	127	16	(	(	PUNCT
fnp-3317	127	17	4r	4r	NOUN
fnp-3317	127	18	)	)	PUNCT
fnp-3317	127	19	,	,	PUNCT
fnp-3317	127	20	which	which	PRON
fnp-3317	127	21	differs	differ	VERB
fnp-3317	127	22	from	from	ADP
fnp-3317	127	23	pick	pick	NOUN
fnp-3317	127	24	disease	disease	NOUN
fnp-3317	127	25	which	which	PRON
fnp-3317	127	26	is	be	AUX
fnp-3317	127	27	composed	compose	VERB
fnp-3317	127	28	of	of	ADP
fnp-3317	127	29	3r	3r	NUM
fnp-3317	127	30	tau	tau	PROPN
fnp-3317	127	31	as	as	ADV
fnp-3317	127	32	well	well	ADV
fnp-3317	127	33	as	as	ADP
fnp-3317	127	34	ad	ad	NOUN
fnp-3317	127	35	and	and	CCONJ
fnp-3317	127	36	cte	cte	NOUN
fnp-3317	127	37	which	which	PRON
fnp-3317	127	38	are	be	AUX
fnp-3317	127	39	mixed	mixed	ADJ
fnp-3317	127	40	3r	3r	NUM
fnp-3317	127	41	and	and	CCONJ
fnp-3317	127	42	4r	4r	NOUN
fnp-3317	127	43	.	.	PUNCT
fnp-3317	128	1	additional	additional	ADJ
fnp-3317	128	2	future	future	ADJ
fnp-3317	128	3	studies	study	NOUN
fnp-3317	128	4	directed	direct	VERB
fnp-3317	128	5	towards	towards	ADP
fnp-3317	128	6	further	further	ADJ
fnp-3317	128	7	delineation	delineation	NOUN
fnp-3317	128	8	of	of	ADP
fnp-3317	128	9	the	the	DET
fnp-3317	128	10	diversity	diversity	NOUN
fnp-3317	128	11	of	of	ADP
fnp-3317	128	12	tau	tau	PROPN
fnp-3317	128	13	filament	filament	NOUN
fnp-3317	128	14	structures	structure	NOUN
fnp-3317	128	15	has	have	VERB
fnp-3317	128	16	the	the	DET
fnp-3317	128	17	potential	potential	NOUN
fnp-3317	128	18	to	to	PART
fnp-3317	128	19	pave	pave	VERB
fnp-3317	128	20	the	the	DET
fnp-3317	128	21	way	way	NOUN
fnp-3317	128	22	towards	towards	ADP
fnp-3317	128	23	improved	improved	ADJ
fnp-3317	128	24	diagnostics	diagnostic	NOUN
fnp-3317	128	25	and	and	CCONJ
fnp-3317	128	26	advancing	advance	VERB
fnp-3317	128	27	our	our	PRON
fnp-3317	128	28	understanding	understanding	NOUN
fnp-3317	128	29	of	of	ADP
fnp-3317	128	30	the	the	DET
fnp-3317	128	31	diversity	diversity	NOUN
fnp-3317	128	32	of	of	ADP
fnp-3317	128	33	conformers	conformer	NOUN
fnp-3317	128	34	in	in	ADP
fnp-3317	128	35	tauopathy	tauopathy	NOUN
fnp-3317	128	36	that	that	PRON
fnp-3317	128	37	may	may	AUX
fnp-3317	128	38	be	be	AUX
fnp-3317	128	39	associated	associate	VERB
fnp-3317	128	40	with	with	ADP
fnp-3317	128	41	different	different	ADJ
fnp-3317	128	42	clinical	clinical	ADJ
fnp-3317	128	43	symptomatology	symptomatology	NOUN
fnp-3317	128	44	.	.	PUNCT
fnp-3317	129	1	figure	figure	NOUN
fnp-3317	129	2	4	4	NUM
fnp-3317	129	3	.	.	PUNCT
fnp-3317	130	1	cryo	cryo	NOUN
fnp-3317	130	2	-	-	PUNCT
fnp-3317	130	3	em	em	PRON
fnp-3317	130	4	of	of	ADP
fnp-3317	130	5	tau	tau	PROPN
fnp-3317	130	6	filaments	filament	NOUN
fnp-3317	130	7	in	in	ADP
fnp-3317	130	8	corticobasal	corticobasal	NOUN
fnp-3317	130	9	degeneration	degeneration	NOUN
fnp-3317	130	10	.	.	PUNCT
fnp-3317	131	1	a.	a.	NOUN
fnp-3317	131	2	negative	negative	ADJ
fnp-3317	131	3	-	-	PUNCT
fnp-3317	131	4	stain	stain	NOUN
fnp-3317	131	5	electron	electron	NOUN
fnp-3317	131	6	micrographs	micrograph	NOUN
fnp-3317	131	7	of	of	ADP
fnp-3317	131	8	type	type	NOUN
fnp-3317	131	9	i	i	PRON
fnp-3317	131	10	and	and	CCONJ
fnp-3317	131	11	type	type	PROPN
fnp-3317	131	12	ii	ii	PROPN
fnp-3317	131	13	tau	tau	PROPN
fnp-3317	131	14	filaments	filament	NOUN
fnp-3317	131	15	extracted	extract	VERB
fnp-3317	131	16	from	from	ADP
fnp-3317	131	17	the	the	DET
fnp-3317	131	18	frontal	frontal	ADJ
fnp-3317	131	19	cortex	cortex	NOUN
fnp-3317	131	20	of	of	ADP
fnp-3317	131	21	cbd	cbd	PROPN
fnp-3317	131	22	.	.	PUNCT
fnp-3317	132	1	b.	b.	PROPN
fnp-3317	132	2	cryo	cryo	PROPN
fnp-3317	132	3	-	-	PUNCT
fnp-3317	132	4	em	em	PRON
fnp-3317	132	5	maps	map	NOUN
fnp-3317	132	6	of	of	ADP
fnp-3317	132	7	type	type	NOUN
fnp-3317	132	8	i	i	PRON
fnp-3317	132	9	and	and	CCONJ
fnp-3317	132	10	type	type	PROPN
fnp-3317	132	11	ii	ii	PROPN
fnp-3317	132	12	tau	tau	PROPN
fnp-3317	132	13	filaments	filament	VERB
fnp-3317	132	14	from	from	ADP
fnp-3317	132	15	the	the	DET
fnp-3317	132	16	frontal	frontal	ADJ
fnp-3317	132	17	cortex	cortex	NOUN
fnp-3317	132	18	of	of	ADP
fnp-3317	132	19	cbd	cbd	PROPN
fnp-3317	132	20	.	.	PUNCT
fnp-3317	133	1	c.	c.	PROPN
fnp-3317	133	2	top	top	PROPN
fnp-3317	133	3	,	,	PUNCT
fnp-3317	133	4	the	the	DET
fnp-3317	133	5	microtubule	microtubule	NOUN
fnp-3317	133	6	-	-	PUNCT
fnp-3317	133	7	binding	bind	VERB
fnp-3317	133	8	repeats	repeat	NOUN
fnp-3317	133	9	(	(	PUNCT
fnp-3317	133	10	r1	r1	NOUN
fnp-3317	133	11	–	–	PUNCT
fnp-3317	133	12	r4	r4	NOUN
fnp-3317	133	13	)	)	PUNCT
fnp-3317	133	14	of	of	ADP
fnp-3317	133	15	tau	tau	PROPN
fnp-3317	133	16	and	and	CCONJ
fnp-3317	133	17	the	the	DET
fnp-3317	133	18	sequence	sequence	NOUN
fnp-3317	133	19	after	after	ADP
fnp-3317	133	20	r4	r4	NOUN
fnp-3317	133	21	that	that	PRON
fnp-3317	133	22	is	be	AUX
fnp-3317	133	23	present	present	ADJ
fnp-3317	133	24	in	in	ADP
fnp-3317	133	25	the	the	DET
fnp-3317	133	26	core	core	NOUN
fnp-3317	133	27	of	of	ADP
fnp-3317	133	28	cbd	cbd	NOUN
fnp-3317	133	29	filaments	filament	NOUN
fnp-3317	133	30	(	(	PUNCT
fnp-3317	133	31	all	all	PRON
fnp-3317	133	32	shown	show	VERB
fnp-3317	133	33	in	in	ADP
fnp-3317	133	34	different	different	ADJ
fnp-3317	133	35	colors	color	NOUN
fnp-3317	133	36	)	)	PUNCT
fnp-3317	133	37	.	.	PUNCT
fnp-3317	134	1	bottom	bottom	ADJ
fnp-3317	134	2	,	,	PUNCT
fnp-3317	134	3	atomic	atomic	ADJ
fnp-3317	134	4	model	model	NOUN
fnp-3317	134	5	of	of	ADP
fnp-3317	134	6	the	the	DET
fnp-3317	134	7	cbd	cbd	PROPN
fnp-3317	134	8	type	type	PROPN
fnp-3317	134	9	ii	ii	PROPN
fnp-3317	134	10	tau	tau	PROPN
fnp-3317	134	11	filament	filament	NOUN
fnp-3317	134	12	.	.	PUNCT
fnp-3317	135	1	the	the	DET
fnp-3317	135	2	extra	extra	ADJ
fnp-3317	135	3	density	density	NOUN
fnp-3317	135	4	is	be	AUX
fnp-3317	135	5	shown	show	VERB
fnp-3317	135	6	in	in	ADP
fnp-3317	135	7	light	light	ADJ
fnp-3317	135	8	blue	blue	NOUN
fnp-3317	135	9	,	,	PUNCT
fnp-3317	135	10	with	with	ADP
fnp-3317	135	11	k290	k290	PROPN
fnp-3317	135	12	,	,	PUNCT
fnp-3317	135	13	k294	k294	PROPN
fnp-3317	135	14	and	and	CCONJ
fnp-3317	135	15	k370	k370	PROPN
fnp-3317	135	16	indicated	indicate	VERB
fnp-3317	135	17	.	.	PUNCT
fnp-3317	136	1	images	image	NOUN
fnp-3317	136	2	courtesy	courtesy	NOUN
fnp-3317	136	3	of	of	ADP
fnp-3317	136	4	drs	dr	NOUN
fnp-3317	136	5	.	.	PUNCT
fnp-3317	137	1	wenjuan	wenjuan	PROPN
fnp-3317	137	2	zhang	zhang	PROPN
fnp-3317	137	3	,	,	PUNCT
fnp-3317	137	4	sjors	sjor	NOUN
fnp-3317	137	5	scheres	schere	NOUN
fnp-3317	137	6	and	and	CCONJ
fnp-3317	137	7	michel	michel	PROPN
fnp-3317	137	8	goedert	goedert	PROPN
fnp-3317	137	9	mrc	mrc	PROPN
fnp-3317	137	10	laboratory	laboratory	NOUN
fnp-3317	137	11	of	of	ADP
fnp-3317	137	12	molecular	molecular	ADJ
fnp-3317	137	13	biology	biology	NOUN
fnp-3317	137	14	,	,	PUNCT
fnp-3317	137	15	cambridge	cambridge	PROPN
fnp-3317	137	16	)	)	PUNCT
fnp-3317	137	17	.	.	PUNCT
fnp-3317	138	1	7	7	X
fnp-3317	138	2	.	.	X
fnp-3317	138	3	cryo	cryo	NOUN
fnp-3317	138	4	-	-	PUNCT
fnp-3317	138	5	electron	electron	NOUN
fnp-3317	138	6	microscopy	microscopy	NOUN
fnp-3317	138	7	:	:	PUNCT
fnp-3317	138	8	ultrahigh	ultrahigh	ADJ
fnp-3317	138	9	resolution	resolution	NOUN
fnp-3317	138	10	structures	structure	NOUN
fnp-3317	138	11	of	of	ADP
fnp-3317	138	12	α	α	NOUN
fnp-3317	138	13	-	-	PUNCT
fnp-3317	138	14	synuclein	synuclein	ADJ
fnp-3317	138	15	conformers	conformer	NOUN
fnp-3317	138	16	this	this	DET
fnp-3317	138	17	year	year	NOUN
fnp-3317	138	18	we	we	PRON
fnp-3317	138	19	also	also	ADV
fnp-3317	138	20	saw	see	VERB
fnp-3317	138	21	reports	report	NOUN
fnp-3317	138	22	of	of	ADP
fnp-3317	138	23	the	the	DET
fnp-3317	138	24	first	first	ADJ
fnp-3317	138	25	ultrahigh	ultrahigh	ADJ
fnp-3317	138	26	resolution	resolution	NOUN
fnp-3317	138	27	cryo	cryo	NOUN
fnp-3317	138	28	-	-	PUNCT
fnp-3317	138	29	em	em	PRON
fnp-3317	138	30	structures	structure	NOUN
fnp-3317	138	31	of	of	ADP
fnp-3317	138	32	α	α	NOUN
fnp-3317	138	33	-	-	PUNCT
fnp-3317	138	34	synuclein	synuclein	NOUN
fnp-3317	138	35	fibrils	fibril	NOUN
fnp-3317	138	36	published	publish	VERB
fnp-3317	138	37	in	in	ADP
fnp-3317	138	38	nature	nature	NOUN
fnp-3317	138	39	also	also	ADV
fnp-3317	138	40	from	from	ADP
fnp-3317	138	41	sjors	sjor	NOUN
fnp-3317	138	42	scheres	schere	NOUN
fnp-3317	138	43	and	and	CCONJ
fnp-3317	138	44	michel	michel	PROPN
fnp-3317	138	45	goedert	goedert	PROPN
fnp-3317	138	46	at	at	ADP
fnp-3317	138	47	the	the	DET
fnp-3317	138	48	mrc	mrc	NOUN
fnp-3317	138	49	laboratory	laboratory	NOUN
fnp-3317	138	50	of	of	ADP
fnp-3317	138	51	molecular	molecular	ADJ
fnp-3317	138	52	biology	biology	NOUN
fnp-3317	138	53	(	(	PUNCT
fnp-3317	138	54	schweighauser	schweighauser	NOUN
fnp-3317	138	55	et	et	NOUN
fnp-3317	138	56	al	al	PROPN
fnp-3317	138	57	.	.	PROPN
fnp-3317	138	58	,	,	PUNCT
fnp-3317	138	59	2020	2020	NUM
fnp-3317	138	60	)	)	PUNCT
fnp-3317	138	61	.	.	PUNCT
fnp-3317	139	1	the	the	DET
fnp-3317	139	2	synucleinopathies	synucleinopathie	NOUN
fnp-3317	139	3	are	be	AUX
fnp-3317	139	4	a	a	DET
fnp-3317	139	5	group	group	NOUN
fnp-3317	139	6	of	of	ADP
fnp-3317	139	7	neurodegenerative	neurodegenerative	ADJ
fnp-3317	139	8	disorders	disorder	NOUN
fnp-3317	139	9	that	that	PRON
fnp-3317	139	10	include	include	VERB
fnp-3317	139	11	parkinson	parkinson	NOUN
fnp-3317	139	12	’s	’s	PART
fnp-3317	139	13	disease	disease	NOUN
fnp-3317	139	14	(	(	PUNCT
fnp-3317	139	15	pd	pd	NOUN
fnp-3317	139	16	)	)	PUNCT
fnp-3317	139	17	,	,	PUNCT
fnp-3317	139	18	pd	pd	PROPN
fnp-3317	139	19	dementia	dementia	PROPN
fnp-3317	139	20	,	,	PUNCT
fnp-3317	139	21	diffuse	diffuse	PROPN
fnp-3317	139	22	lewy	lewy	ADJ
fnp-3317	139	23	body	body	NOUN
fnp-3317	139	24	disease	disease	NOUN
fnp-3317	139	25	(	(	PUNCT
fnp-3317	139	26	dlbd	dlbd	X
fnp-3317	139	27	)	)	PUNCT
fnp-3317	139	28	and	and	CCONJ
fnp-3317	139	29	multiple	multiple	ADJ
fnp-3317	139	30	system	system	NOUN
fnp-3317	139	31	atrophy	atrophy	NOUN
fnp-3317	139	32	(	(	PUNCT
fnp-3317	139	33	msa	msa	PROPN
fnp-3317	139	34	)	)	PUNCT
fnp-3317	139	35	.	.	PUNCT
fnp-3317	140	1	co	co	VERB
fnp-3317	140	2	-	-	ADJ
fnp-3317	140	3	first	first	ADJ
fnp-3317	140	4	authors	author	NOUN
fnp-3317	140	5	schweighauser	schweighauser	VERB
fnp-3317	140	6	and	and	CCONJ
fnp-3317	140	7	shi	shi	PROPN
fnp-3317	140	8	et	et	PROPN
fnp-3317	140	9	al	al	PROPN
fnp-3317	140	10	.	.	PROPN
fnp-3317	140	11	,	,	PUNCT
fnp-3317	140	12	studied	study	VERB
fnp-3317	140	13	three	three	NUM
fnp-3317	140	14	cases	case	NOUN
fnp-3317	140	15	of	of	ADP
fnp-3317	140	16	dlbd	dlbd	NOUN
fnp-3317	140	17	and	and	CCONJ
fnp-3317	140	18	five	five	NUM
fnp-3317	140	19	with	with	ADP
fnp-3317	140	20	msa	msa	PROPN
fnp-3317	140	21	.	.	PROPN
fnp-3317	141	1	in	in	ADP
fnp-3317	141	2	msa	msa	PROPN
fnp-3317	141	3	,	,	PUNCT
fnp-3317	141	4	they	they	PRON
fnp-3317	141	5	found	find	VERB
fnp-3317	141	6	two	two	NUM
fnp-3317	141	7	types	type	NOUN
fnp-3317	141	8	of	of	ADP
fnp-3317	141	9	filament	filament	NOUN
fnp-3317	141	10	,	,	PUNCT
fnp-3317	141	11	that	that	SCONJ
fnp-3317	141	12	they	they	PRON
fnp-3317	141	13	termed	term	VERB
fnp-3317	141	14	type	type	NOUN
fnp-3317	141	15	1	1	NUM
fnp-3317	141	16	and	and	CCONJ
fnp-3317	141	17	type	type	NOUN
fnp-3317	141	18	2	2	NUM
fnp-3317	141	19	,	,	PUNCT
fnp-3317	141	20	each	each	PRON
fnp-3317	141	21	with	with	ADP
fnp-3317	141	22	filaments	filament	NOUN
fnp-3317	141	23	with	with	ADP
fnp-3317	141	24	different	different	ADJ
fnp-3317	141	25	protofibrils	protofibril	NOUN
fnp-3317	141	26	that	that	PRON
fnp-3317	141	27	make	make	VERB
fnp-3317	141	28	up	up	ADP
fnp-3317	141	29	the	the	DET
fnp-3317	141	30	core	core	NOUN
fnp-3317	141	31	.	.	PUNCT
fnp-3317	142	1	the	the	DET
fnp-3317	142	2	conformation	conformation	NOUN
fnp-3317	142	3	of	of	ADP
fnp-3317	142	4	α	α	PROPN
fnp-3317	142	5	-	-	PUNCT
fnp-3317	142	6	synuclein	synuclein	ADJ
fnp-3317	142	7	filaments	filament	NOUN
fnp-3317	142	8	derived	derive	VERB
fnp-3317	142	9	from	from	ADP
fnp-3317	142	10	dlbd	dlbd	NOUN
fnp-3317	142	11	brains	brain	NOUN
fnp-3317	142	12	by	by	ADP
fnp-3317	142	13	cryo	cryo	NOUN
fnp-3317	142	14	-	-	PUNCT
fnp-3317	142	15	em	em	PRON
fnp-3317	142	16	precluded	preclude	VERB
fnp-3317	142	17	3d	3d	NUM
fnp-3317	142	18	imaging	imaging	NOUN
fnp-3317	142	19	,	,	PUNCT
fnp-3317	142	20	so	so	CCONJ
fnp-3317	142	21	2d	2d	NOUN
fnp-3317	142	22	class	class	NOUN
fnp-3317	142	23	averaging	averaging	NOUN
fnp-3317	142	24	was	be	AUX
fnp-3317	142	25	used	use	VERB
fnp-3317	142	26	to	to	PART
fnp-3317	142	27	show	show	VERB
fnp-3317	142	28	that	that	SCONJ
fnp-3317	142	29	there	there	PRON
fnp-3317	142	30	were	be	VERB
fnp-3317	142	31	differences	difference	NOUN
fnp-3317	142	32	in	in	ADP
fnp-3317	142	33	the	the	DET
fnp-3317	142	34	structure	structure	NOUN
fnp-3317	142	35	from	from	ADP
fnp-3317	142	36	msa	msa	PROPN
fnp-3317	142	37	.	.	PUNCT
fnp-3317	143	1	overall	overall	ADV
fnp-3317	143	2	,	,	PUNCT
fnp-3317	143	3	these	these	DET
fnp-3317	143	4	structural	structural	ADJ
fnp-3317	143	5	differences	difference	NOUN
fnp-3317	143	6	are	be	AUX
fnp-3317	143	7	of	of	ADP
fnp-3317	143	8	great	great	ADJ
fnp-3317	143	9	interest	interest	NOUN
fnp-3317	143	10	as	as	ADP
fnp-3317	143	11	accumulating	accumulate	VERB
fnp-3317	143	12	evidence	evidence	NOUN
fnp-3317	143	13	suggests	suggest	VERB
fnp-3317	143	14	that	that	SCONJ
fnp-3317	143	15	α	α	X
fnp-3317	143	16	-	-	PUNCT
fnp-3317	143	17	synuclein	synuclein	NOUN
fnp-3317	143	18	might	might	AUX
fnp-3317	143	19	behave	behave	VERB
fnp-3317	143	20	in	in	ADP
fnp-3317	143	21	a	a	DET
fnp-3317	143	22	prion	prion	NOUN
fnp-3317	143	23	-	-	PUNCT
fnp-3317	143	24	like	like	ADJ
fnp-3317	143	25	manner	manner	NOUN
fnp-3317	143	26	,	,	PUNCT
fnp-3317	143	27	with	with	ADP
fnp-3317	143	28	templating	templating	NOUN
fnp-3317	143	29	and	and	CCONJ
fnp-3317	143	30	propagation	propagation	NOUN
fnp-3317	143	31	of	of	ADP
fnp-3317	143	32	abnormal	abnormal	ADJ
fnp-3317	143	33	structures	structure	NOUN
fnp-3317	143	34	/	/	SYM
fnp-3317	143	35	conformers	conformer	NOUN
fnp-3317	143	36	.	.	PUNCT
fnp-3317	144	1	this	this	DET
fnp-3317	144	2	knowledge	knowledge	NOUN
fnp-3317	144	3	may	may	AUX
fnp-3317	144	4	be	be	AUX
fnp-3317	144	5	helpful	helpful	ADJ
fnp-3317	144	6	in	in	ADP
fnp-3317	144	7	understanding	understand	VERB
fnp-3317	144	8	the	the	DET
fnp-3317	144	9	pathogenesis	pathogenesis	NOUN
fnp-3317	144	10	and	and	CCONJ
fnp-3317	144	11	natural	natural	ADJ
fnp-3317	144	12	history	history	NOUN
fnp-3317	144	13	of	of	ADP
fnp-3317	144	14	the	the	DET
fnp-3317	144	15	synucleinopathies	synucleinopathie	NOUN
fnp-3317	144	16	,	,	PUNCT
fnp-3317	144	17	and	and	CCONJ
fnp-3317	144	18	especially	especially	ADV
fnp-3317	144	19	in	in	ADP
fnp-3317	144	20	the	the	DET
fnp-3317	144	21	development	development	NOUN
fnp-3317	144	22	of	of	ADP
fnp-3317	144	23	specific	specific	ADJ
fnp-3317	144	24	α	α	NOUN
fnp-3317	144	25	-	-	PUNCT
fnp-3317	144	26	synuclein	synuclein	ADJ
fnp-3317	144	27	pet	pet	ADJ
fnp-3317	144	28	tracers	tracer	NOUN
fnp-3317	144	29	,	,	PUNCT
fnp-3317	144	30	which	which	PRON
fnp-3317	144	31	have	have	AUX
fnp-3317	144	32	been	be	AUX
fnp-3317	144	33	so	so	ADV
fnp-3317	144	34	far	far	ADV
fnp-3317	144	35	elusive	elusive	ADJ
fnp-3317	144	36	.	.	PUNCT
fnp-3317	145	1	8	8	X
fnp-3317	145	2	.	.	X
fnp-3317	145	3	characterizing	characterize	VERB
fnp-3317	145	4	α	α	NOUN
fnp-3317	145	5	-	-	PUNCT
fnp-3317	145	6	synuclein	synuclein	NOUN
fnp-3317	145	7	strains	strain	VERB
fnp-3317	145	8	the	the	DET
fnp-3317	145	9	α	α	NOUN
fnp-3317	145	10	-	-	PUNCT
fnp-3317	145	11	synucleinopathies	synucleinopathie	NOUN
fnp-3317	145	12	,	,	PUNCT
fnp-3317	145	13	including	include	VERB
fnp-3317	145	14	parkinson	parkinson	NOUN
fnp-3317	145	15	disease	disease	NOUN
fnp-3317	145	16	,	,	PUNCT
fnp-3317	145	17	diffuse	diffuse	PROPN
fnp-3317	145	18	lewy	lewy	ADJ
fnp-3317	145	19	body	body	NOUN
fnp-3317	145	20	disease	disease	NOUN
fnp-3317	145	21	,	,	PUNCT
fnp-3317	145	22	and	and	CCONJ
fnp-3317	145	23	dementia	dementia	NOUN
fnp-3317	145	24	with	with	ADP
fnp-3317	145	25	lewy	lewy	ADJ
fnp-3317	145	26	bodies	body	NOUN
fnp-3317	145	27	,	,	PUNCT
fnp-3317	145	28	while	while	SCONJ
fnp-3317	145	29	linked	link	VERB
fnp-3317	145	30	by	by	ADP
fnp-3317	145	31	aggregation	aggregation	NOUN
fnp-3317	145	32	of	of	ADP
fnp-3317	145	33	α	α	NOUN
fnp-3317	145	34	-	-	PUNCT
fnp-3317	145	35	synuclein	synuclein	NOUN
fnp-3317	145	36	,	,	PUNCT
fnp-3317	145	37	have	have	AUX
fnp-3317	145	38	been	be	AUX
fnp-3317	145	39	hypothesized	hypothesize	VERB
fnp-3317	145	40	to	to	PART
fnp-3317	145	41	diverge	diverge	VERB
fnp-3317	145	42	based	base	VERB
fnp-3317	145	43	on	on	ADP
fnp-3317	145	44	the	the	DET
fnp-3317	145	45	prion	prion	NOUN
fnp-3317	145	46	-	-	PUNCT
fnp-3317	145	47	like	like	ADJ
fnp-3317	145	48	properties	property	NOUN
fnp-3317	145	49	unique	unique	ADJ
fnp-3317	145	50	disease	disease	NOUN
fnp-3317	145	51	conformational	conformational	ADJ
fnp-3317	145	52	structural	structural	ADJ
fnp-3317	145	53	folding	folding	NOUN
fnp-3317	145	54	that	that	PRON
fnp-3317	145	55	templates	template	VERB
fnp-3317	145	56	replication	replication	NOUN
fnp-3317	145	57	of	of	ADP
fnp-3317	145	58	the	the	DET
fnp-3317	145	59	abnormality	abnormality	NOUN
fnp-3317	145	60	.	.	PUNCT
fnp-3317	146	1	these	these	DET
fnp-3317	146	2	strains	strain	NOUN
fnp-3317	146	3	are	be	AUX
fnp-3317	146	4	hypothesized	hypothesize	VERB
fnp-3317	146	5	to	to	PART
fnp-3317	146	6	have	have	VERB
fnp-3317	146	7	different	different	ADJ
fnp-3317	146	8	properties	property	NOUN
fnp-3317	146	9	and	and	CCONJ
fnp-3317	146	10	may	may	AUX
fnp-3317	146	11	influence	influence	VERB
fnp-3317	146	12	neuropathological	neuropathological	ADJ
fnp-3317	146	13	features	feature	NOUN
fnp-3317	146	14	and	and	CCONJ
fnp-3317	146	15	symptomatology	symptomatology	NOUN
fnp-3317	146	16	.	.	PUNCT
fnp-3317	147	1	this	this	DET
fnp-3317	147	2	year	year	NOUN
fnp-3317	147	3	,	,	PUNCT
fnp-3317	147	4	a	a	DET
fnp-3317	147	5	study	study	NOUN
fnp-3317	147	6	was	be	AUX
fnp-3317	147	7	published	publish	VERB
fnp-3317	147	8	that	that	PRON
fnp-3317	147	9	took	take	VERB
fnp-3317	147	10	us	we	PRON
fnp-3317	147	11	one	one	NUM
fnp-3317	147	12	step	step	NOUN
fnp-3317	147	13	closer	close	ADV
fnp-3317	147	14	to	to	ADP
fnp-3317	147	15	understanding	understand	VERB
fnp-3317	147	16	the	the	DET
fnp-3317	147	17	pathobiology	pathobiology	NOUN
fnp-3317	147	18	and	and	CCONJ
fnp-3317	147	19	diversity	diversity	NOUN
fnp-3317	147	20	of	of	ADP
fnp-3317	147	21	α	α	NOUN
fnp-3317	147	22	-	-	PUNCT
fnp-3317	147	23	synuclein	synuclein	NOUN
fnp-3317	147	24	strains	strain	NOUN
fnp-3317	147	25	.	.	PUNCT
fnp-3317	148	1	in	in	ADP
fnp-3317	148	2	an	an	DET
fnp-3317	148	3	elegant	elegant	ADJ
fnp-3317	148	4	set	set	NOUN
fnp-3317	148	5	of	of	ADP
fnp-3317	148	6	experiments	experiment	NOUN
fnp-3317	148	7	,	,	PUNCT
fnp-3317	148	8	lau	lau	PROPN
fnp-3317	148	9	et	et	PROPN
fnp-3317	148	10	al	al	PROPN
fnp-3317	148	11	.	.	PROPN
fnp-3317	148	12	recreated	recreate	VERB
fnp-3317	148	13	an	an	DET
fnp-3317	148	14	array	array	NOUN
fnp-3317	148	15	of	of	ADP
fnp-3317	148	16	α	α	NOUN
fnp-3317	148	17	-	-	PUNCT
fnp-3317	148	18	synuclein	synuclein	NOUN
fnp-3317	148	19	fibrils	fibril	NOUN
fnp-3317	148	20	with	with	ADP
fnp-3317	148	21	different	different	ADJ
fnp-3317	148	22	confirmations	confirmation	NOUN
fnp-3317	148	23	in	in	ADP
fnp-3317	148	24	vitro	vitro	X
fnp-3317	148	25	using	use	VERB
fnp-3317	148	26	recombinant	recombinant	ADJ
fnp-3317	148	27	proteins	protein	NOUN
fnp-3317	148	28	by	by	ADP
fnp-3317	148	29	altering	alter	VERB
fnp-3317	148	30	buffer	buffer	NOUN
fnp-3317	148	31	conditions	condition	NOUN
fnp-3317	148	32	(	(	PUNCT
fnp-3317	148	33	lau	lau	PROPN
fnp-3317	148	34	et	et	PROPN
fnp-3317	148	35	al	al	PROPN
fnp-3317	148	36	.	.	PROPN
fnp-3317	148	37	,	,	PUNCT
fnp-3317	148	38	2020	2020	NUM
fnp-3317	148	39	)	)	PUNCT
fnp-3317	148	40	.	.	PUNCT
fnp-3317	149	1	they	they	PRON
fnp-3317	149	2	generated	generate	VERB
fnp-3317	149	3	a	a	DET
fnp-3317	149	4	host	host	NOUN
fnp-3317	149	5	of	of	ADP
fnp-3317	149	6	fibrils	fibril	NOUN
fnp-3317	149	7	that	that	PRON
fnp-3317	149	8	varied	varied	ADJ
fnp-3317	149	9	in	in	ADP
fnp-3317	149	10	their	their	PRON
fnp-3317	149	11	biophysical	biophysical	ADJ
fnp-3317	149	12	properties	property	NOUN
fnp-3317	149	13	and	and	CCONJ
fnp-3317	149	14	compared	compare	VERB
fnp-3317	149	15	them	they	PRON
fnp-3317	149	16	with	with	ADP
fnp-3317	149	17	those	those	PRON
fnp-3317	149	18	derived	derive	VERB
fnp-3317	149	19	from	from	ADP
fnp-3317	149	20	human	human	ADJ
fnp-3317	149	21	post	post	ADJ
fnp-3317	149	22	-	-	ADJ
fnp-3317	149	23	mortem	mortem	ADJ
fnp-3317	149	24	brain	brain	NOUN
fnp-3317	149	25	samples	sample	NOUN
fnp-3317	149	26	.	.	PUNCT
fnp-3317	150	1	then	then	ADV
fnp-3317	150	2	,	,	PUNCT
fnp-3317	150	3	the	the	DET
fnp-3317	150	4	fibrils	fibril	NOUN
fnp-3317	150	5	were	be	AUX
fnp-3317	150	6	inoculated	inoculate	VERB
fnp-3317	150	7	into	into	ADP
fnp-3317	150	8	a	a	DET
fnp-3317	150	9	transgenic	transgenic	NOUN
fnp-3317	150	10	mouse	mouse	NOUN
fnp-3317	150	11	line	line	NOUN
fnp-3317	150	12	that	that	PRON
fnp-3317	150	13	overexpresses	overexpresse	VERB
fnp-3317	150	14	human	human	ADJ
fnp-3317	150	15	mutant	mutant	NOUN
fnp-3317	150	16	α	α	NOUN
fnp-3317	150	17	-	-	PUNCT
fnp-3317	150	18	synuclein	synuclein	NOUN
fnp-3317	150	19	and	and	CCONJ
fnp-3317	150	20	observed	observe	VERB
fnp-3317	150	21	them	they	PRON
fnp-3317	150	22	.	.	PUNCT
fnp-3317	151	1	over	over	ADP
fnp-3317	151	2	time	time	NOUN
fnp-3317	151	3	,	,	PUNCT
fnp-3317	151	4	the	the	DET
fnp-3317	151	5	mice	mouse	NOUN
fnp-3317	151	6	developed	develop	VERB
fnp-3317	151	7	a	a	DET
fnp-3317	151	8	range	range	NOUN
fnp-3317	151	9	of	of	ADP
fnp-3317	151	10	traits	trait	NOUN
fnp-3317	151	11	that	that	PRON
fnp-3317	151	12	were	be	AUX
fnp-3317	151	13	strain	strain	ADJ
fnp-3317	151	14	specific	specific	ADJ
fnp-3317	151	15	,	,	PUNCT
fnp-3317	151	16	including	include	VERB
fnp-3317	151	17	aggregate	aggregate	ADJ
fnp-3317	151	18	morphology	morphology	NOUN
fnp-3317	151	19	,	,	PUNCT
fnp-3317	151	20	incubation	incubation	NOUN
fnp-3317	151	21	periods	period	NOUN
fnp-3317	151	22	and	and	CCONJ
fnp-3317	151	23	behavioral	behavioral	ADJ
fnp-3317	151	24	changes	change	NOUN
fnp-3317	151	25	,	,	PUNCT
fnp-3317	151	26	that	that	PRON
fnp-3317	151	27	could	could	AUX
fnp-3317	151	28	be	be	AUX
fnp-3317	151	29	propagated	propagate	VERB
fnp-3317	151	30	serially	serially	ADV
fnp-3317	151	31	(	(	PUNCT
fnp-3317	151	32	figure	figure	NOUN
fnp-3317	151	33	5	5	NUM
fnp-3317	151	34	)	)	PUNCT
fnp-3317	151	35	.	.	PUNCT
fnp-3317	152	1	in	in	ADP
fnp-3317	152	2	the	the	DET
fnp-3317	152	3	brains	brain	NOUN
fnp-3317	152	4	of	of	ADP
fnp-3317	152	5	these	these	DET
fnp-3317	152	6	animals	animal	NOUN
fnp-3317	152	7	,	,	PUNCT
fnp-3317	152	8	distinct	distinct	ADJ
fnp-3317	152	9	neuroanatomical	neuroanatomical	ADJ
fnp-3317	152	10	vulnerability	vulnerability	NOUN
fnp-3317	152	11	was	be	AUX
fnp-3317	152	12	observed	observe	VERB
fnp-3317	152	13	that	that	PRON
fnp-3317	152	14	was	be	AUX
fnp-3317	152	15	dictated	dictate	VERB
fnp-3317	152	16	by	by	ADP
fnp-3317	152	17	strain	strain	NOUN
fnp-3317	152	18	type	type	NOUN
fnp-3317	152	19	.	.	PUNCT
fnp-3317	153	1	these	these	DET
fnp-3317	153	2	findings	finding	NOUN
fnp-3317	153	3	give	give	VERB
fnp-3317	153	4	us	we	PRON
fnp-3317	153	5	an	an	DET
fnp-3317	153	6	additional	additional	ADJ
fnp-3317	153	7	model	model	NOUN
fnp-3317	153	8	for	for	ADP
fnp-3317	153	9	testing	test	VERB
fnp-3317	153	10	questions	question	NOUN
fnp-3317	153	11	related	relate	VERB
fnp-3317	153	12	to	to	ADP
fnp-3317	153	13	how	how	SCONJ
fnp-3317	153	14	these	these	DET
fnp-3317	153	15	different	different	ADJ
fnp-3317	153	16	α	α	ADJ
fnp-3317	153	17	-	-	PUNCT
fnp-3317	153	18	synuclein	synuclein	ADJ
fnp-3317	153	19	conformers	conformer	NOUN
fnp-3317	153	20	target	target	VERB
fnp-3317	153	21	specific	specific	ADJ
fnp-3317	153	22	cells	cell	NOUN
fnp-3317	153	23	and	and	CCONJ
fnp-3317	153	24	brain	brain	NOUN
fnp-3317	153	25	regions	region	NOUN
fnp-3317	153	26	leading	lead	VERB
fnp-3317	153	27	to	to	ADP
fnp-3317	153	28	neurodegeneration	neurodegeneration	NOUN
fnp-3317	153	29	.	.	PUNCT
fnp-3317	154	1	figure	figure	NOUN
fnp-3317	154	2	5	5	NUM
fnp-3317	154	3	.	.	PUNCT
fnp-3317	154	4	distinct	distinct	ADJ
fnp-3317	154	5	midbrain	midbrain	NOUN
fnp-3317	154	6	pathology	pathology	NOUN
fnp-3317	154	7	in	in	ADP
fnp-3317	154	8	transgenic	transgenic	NOUN
fnp-3317	154	9	α	α	X
fnp-3317	154	10	-	-	PUNCT
fnp-3317	154	11	synuclein	synuclein	X
fnp-3317	154	12	(	(	PUNCT
fnp-3317	154	13	m83	m83	NOUN
fnp-3317	154	14	)	)	PUNCT
fnp-3317	154	15	mice	mouse	NOUN
fnp-3317	154	16	inoculated	inoculate	VERB
fnp-3317	154	17	with	with	ADP
fnp-3317	154	18	salt	salt	NOUN
fnp-3317	154	19	(	(	PUNCT
fnp-3317	154	20	s	s	NOUN
fnp-3317	154	21	)	)	PUNCT
fnp-3317	154	22	fibrils	fibril	NOUN
fnp-3317	154	23	or	or	CCONJ
fnp-3317	154	24	no	no	DET
fnp-3317	154	25	salt	salt	NOUN
fnp-3317	154	26	(	(	PUNCT
fnp-3317	154	27	ns	ns	NOUN
fnp-3317	154	28	)	)	PUNCT
fnp-3317	154	29	fibrils	fibril	NOUN
fnp-3317	154	30	.	.	PUNCT
fnp-3317	155	1	a.	a.	NOUN
fnp-3317	155	2	the	the	DET
fnp-3317	155	3	ns	ns	NUM
fnp-3317	155	4	fibril	fibril	ADV
fnp-3317	155	5	-	-	PUNCT
fnp-3317	155	6	injected	inject	VERB
fnp-3317	155	7	mice	mouse	NOUN
fnp-3317	155	8	show	show	VERB
fnp-3317	155	9	the	the	DET
fnp-3317	155	10	“	"	PUNCT
fnp-3317	155	11	lewy	lewy	ADJ
fnp-3317	155	12	body	body	NOUN
fnp-3317	155	13	-	-	PUNCT
fnp-3317	155	14	like	like	ADJ
fnp-3317	155	15	”	"	PUNCT
fnp-3317	155	16	α	α	NOUN
fnp-3317	155	17	-	-	PUNCT
fnp-3317	155	18	synuclein	synuclein	NOUN
fnp-3317	155	19	pathology	pathology	NOUN
fnp-3317	155	20	.	.	PUNCT
fnp-3317	156	1	b.	b.	VERB
fnp-3317	157	1	the	the	DET
fnp-3317	157	2	s	s	NOUN
fnp-3317	157	3	fibril	fibril	ADV
fnp-3317	157	4	-	-	PUNCT
fnp-3317	157	5	injected	inject	VERB
fnp-3317	157	6	mice	mice	NOUN
fnp-3317	157	7	exhibit	exhibit	VERB
fnp-3317	157	8	the	the	DET
fnp-3317	157	9	“	"	PUNCT
fnp-3317	157	10	ring	ring	NOUN
fnp-3317	157	11	-	-	PUNCT
fnp-3317	157	12	like	like	ADJ
fnp-3317	157	13	”	"	PUNCT
fnp-3317	157	14	α	α	NOUN
fnp-3317	157	15	-	-	PUNCT
fnp-3317	157	16	synuclein	synuclein	NOUN
fnp-3317	157	17	pathology	pathology	NOUN
fnp-3317	157	18	.	.	PUNCT
fnp-3317	158	1	both	both	DET
fnp-3317	158	2	images	image	NOUN
fnp-3317	158	3	show	show	VERB
fnp-3317	158	4	stains	stain	NOUN
fnp-3317	158	5	with	with	ADP
fnp-3317	158	6	the	the	DET
fnp-3317	158	7	ep1536y	ep1536y	ADJ
fnp-3317	158	8	antibody	antibody	NOUN
fnp-3317	158	9	that	that	PRON
fnp-3317	158	10	recognizes	recognize	VERB
fnp-3317	158	11	synuclein	synuclein	NOUN
fnp-3317	158	12	phosphorylated	phosphorylate	VERB
fnp-3317	158	13	at	at	ADP
fnp-3317	158	14	serine	serine	NOUN
fnp-3317	158	15	129	129	NUM
fnp-3317	158	16	.	.	PUNCT
fnp-3317	159	1	images	image	NOUN
fnp-3317	159	2	courtesy	courtesy	NOUN
fnp-3317	159	3	of	of	ADP
fnp-3317	159	4	dr	dr	PROPN
fnp-3317	159	5	.	.	PROPN
fnp-3317	159	6	joel	joel	PROPN
fnp-3317	159	7	watts	watts	PROPN
fnp-3317	159	8	(	(	PUNCT
fnp-3317	159	9	university	university	NOUN
fnp-3317	159	10	of	of	ADP
fnp-3317	159	11	toronto	toronto	PROPN
fnp-3317	159	12	)	)	PUNCT
fnp-3317	159	13	.	.	PUNCT
fnp-3317	160	1	9	9	X
fnp-3317	160	2	.	.	X
fnp-3317	160	3	huntington	huntington	PROPN
fnp-3317	160	4	’s	’s	PART
fnp-3317	160	5	disease	disease	NOUN
fnp-3317	160	6	and	and	CCONJ
fnp-3317	160	7	chorea	chorea	NOUN
fnp-3317	160	8	abnormalities	abnormality	NOUN
fnp-3317	160	9	in	in	ADP
fnp-3317	160	10	proteostasis	proteostasis	NOUN
fnp-3317	160	11	are	be	AUX
fnp-3317	160	12	a	a	DET
fnp-3317	160	13	key	key	ADJ
fnp-3317	160	14	feature	feature	NOUN
fnp-3317	160	15	of	of	ADP
fnp-3317	160	16	essentially	essentially	ADV
fnp-3317	160	17	all	all	PRON
fnp-3317	160	18	neurodegenerative	neurodegenerative	ADJ
fnp-3317	160	19	disorders	disorder	NOUN
fnp-3317	160	20	.	.	PUNCT
fnp-3317	161	1	this	this	DET
fnp-3317	161	2	change	change	NOUN
fnp-3317	161	3	is	be	AUX
fnp-3317	161	4	associated	associate	VERB
fnp-3317	161	5	with	with	ADP
fnp-3317	161	6	endoplasmic	endoplasmic	ADJ
fnp-3317	161	7	reticulum	reticulum	NOUN
fnp-3317	161	8	(	(	PUNCT
fnp-3317	161	9	er	er	INTJ
fnp-3317	161	10	)	)	PUNCT
fnp-3317	161	11	stress	stress	NOUN
fnp-3317	161	12	,	,	PUNCT
fnp-3317	161	13	which	which	PRON
fnp-3317	161	14	then	then	ADV
fnp-3317	161	15	triggers	trigger	VERB
fnp-3317	161	16	the	the	DET
fnp-3317	161	17	unfolded	unfolded	ADJ
fnp-3317	161	18	protein	protein	NOUN
fnp-3317	161	19	response	response	NOUN
fnp-3317	161	20	(	(	PUNCT
fnp-3317	161	21	upr	upr	NOUN
fnp-3317	161	22	)	)	PUNCT
fnp-3317	161	23	.	.	PUNCT
fnp-3317	162	1	xbp1	xbp1	PROPN
fnp-3317	162	2	is	be	AUX
fnp-3317	162	3	a	a	DET
fnp-3317	162	4	key	key	ADJ
fnp-3317	162	5	mediator	mediator	NOUN
fnp-3317	162	6	of	of	ADP
fnp-3317	162	7	the	the	DET
fnp-3317	162	8	er	er	INTJ
fnp-3317	162	9	stress	stress	NOUN
fnp-3317	162	10	response	response	NOUN
fnp-3317	162	11	thought	think	VERB
fnp-3317	162	12	to	to	PART
fnp-3317	162	13	be	be	AUX
fnp-3317	162	14	a	a	DET
fnp-3317	162	15	master	master	NOUN
fnp-3317	162	16	regulator	regulator	NOUN
fnp-3317	162	17	of	of	ADP
fnp-3317	162	18	the	the	DET
fnp-3317	162	19	upr	upr	NOUN
fnp-3317	162	20	that	that	PRON
fnp-3317	162	21	drives	drive	VERB
fnp-3317	162	22	the	the	DET
fnp-3317	162	23	adaptation	adaptation	NOUN
fnp-3317	162	24	response	response	NOUN
fnp-3317	162	25	to	to	PART
fnp-3317	162	26	recover	recover	VERB
fnp-3317	162	27	proteostasis	proteostasis	NOUN
fnp-3317	162	28	through	through	ADP
fnp-3317	162	29	a	a	DET
fnp-3317	162	30	number	number	NOUN
fnp-3317	162	31	of	of	ADP
fnp-3317	162	32	mechanisms	mechanism	NOUN
fnp-3317	162	33	.	.	PUNCT
fnp-3317	163	1	in	in	ADP
fnp-3317	163	2	a	a	DET
fnp-3317	163	3	series	series	NOUN
fnp-3317	163	4	of	of	ADP
fnp-3317	163	5	compelling	compelling	ADJ
fnp-3317	163	6	experiments	experiment	NOUN
fnp-3317	163	7	,	,	PUNCT
fnp-3317	163	8	a	a	DET
fnp-3317	163	9	team	team	NOUN
fnp-3317	163	10	from	from	ADP
fnp-3317	163	11	the	the	DET
fnp-3317	163	12	university	university	NOUN
fnp-3317	163	13	of	of	ADP
fnp-3317	163	14	chile	chile	PROPN
fnp-3317	163	15	showed	show	VERB
fnp-3317	163	16	that	that	SCONJ
fnp-3317	163	17	treatment	treatment	NOUN
fnp-3317	163	18	with	with	ADP
fnp-3317	163	19	igf2	igf2	PROPN
fnp-3317	163	20	,	,	PUNCT
fnp-3317	163	21	a	a	DET
fnp-3317	163	22	factor	factor	NOUN
fnp-3317	163	23	that	that	PRON
fnp-3317	163	24	they	they	PRON
fnp-3317	163	25	previously	previously	ADV
fnp-3317	163	26	implicated	implicate	VERB
fnp-3317	163	27	as	as	ADP
fnp-3317	163	28	a	a	DET
fnp-3317	163	29	downstream	downstream	ADJ
fnp-3317	163	30	effector	effector	NOUN
fnp-3317	163	31	of	of	ADP
fnp-3317	163	32	xbp1	xbp1	PROPN
fnp-3317	163	33	in	in	ADP
fnp-3317	163	34	animal	animal	NOUN
fnp-3317	163	35	models	model	NOUN
fnp-3317	163	36	deficient	deficient	ADJ
fnp-3317	163	37	in	in	ADP
fnp-3317	163	38	xbp1	xbp1	PROPN
fnp-3317	163	39	,	,	PUNCT
fnp-3317	163	40	may	may	AUX
fnp-3317	163	41	be	be	AUX
fnp-3317	163	42	an	an	DET
fnp-3317	163	43	important	important	ADJ
fnp-3317	163	44	contributor	contributor	NOUN
fnp-3317	163	45	to	to	ADP
fnp-3317	163	46	this	this	DET
fnp-3317	163	47	finding	finding	NOUN
fnp-3317	163	48	(	(	PUNCT
fnp-3317	163	49	garcía	garcía	VERB
fnp-3317	163	50	-	-	PUNCT
fnp-3317	163	51	huerta	huerta	PROPN
fnp-3317	163	52	et	et	PROPN
fnp-3317	163	53	al	al	PROPN
fnp-3317	163	54	.	.	PROPN
fnp-3317	163	55	,	,	PUNCT
fnp-3317	163	56	2020	2020	NUM
fnp-3317	163	57	)	)	PUNCT
fnp-3317	163	58	.	.	PUNCT
fnp-3317	164	1	treatment	treatment	NOUN
fnp-3317	164	2	with	with	ADP
fnp-3317	164	3	igf1	igf1	PROPN
fnp-3317	164	4	led	lead	VERB
fnp-3317	164	5	to	to	ADP
fnp-3317	164	6	a	a	DET
fnp-3317	164	7	marked	mark	VERB
fnp-3317	164	8	reduction	reduction	NOUN
fnp-3317	164	9	in	in	ADP
fnp-3317	164	10	the	the	DET
fnp-3317	164	11	burden	burden	NOUN
fnp-3317	164	12	of	of	ADP
fnp-3317	164	13	intracellular	intracellular	ADJ
fnp-3317	164	14	aggregates	aggregate	NOUN
fnp-3317	164	15	of	of	ADP
fnp-3317	164	16	mutant	mutant	ADJ
fnp-3317	164	17	huntingtin	huntingtin	NOUN
fnp-3317	164	18	in	in	ADP
fnp-3317	164	19	cellular	cellular	ADJ
fnp-3317	164	20	models	model	NOUN
fnp-3317	164	21	,	,	PUNCT
fnp-3317	164	22	including	include	VERB
fnp-3317	164	23	an	an	DET
fnp-3317	164	24	induced	induced	ADJ
fnp-3317	164	25	pluripotent	pluripotent	ADJ
fnp-3317	164	26	stem	stem	NOUN
fnp-3317	164	27	cell	cell	NOUN
fnp-3317	164	28	(	(	PUNCT
fnp-3317	164	29	ipsc)-derived	ipsc)-derive	VERB
fnp-3317	164	30	model	model	NOUN
fnp-3317	164	31	of	of	ADP
fnp-3317	164	32	medium	medium	ADJ
fnp-3317	164	33	spiny	spiny	ADJ
fnp-3317	164	34	neurons	neuron	NOUN
fnp-3317	164	35	from	from	ADP
fnp-3317	164	36	hd	hd	NOUN
fnp-3317	164	37	patients	patient	NOUN
fnp-3317	164	38	.	.	PUNCT
fnp-3317	165	1	when	when	SCONJ
fnp-3317	165	2	the	the	DET
fnp-3317	165	3	autophagy	autophagy	NOUN
fnp-3317	165	4	and	and	CCONJ
fnp-3317	165	5	the	the	DET
fnp-3317	165	6	ubiquitin	ubiquitin	ADJ
fnp-3317	165	7	proteasome	proteasome	NOUN
fnp-3317	165	8	were	be	AUX
fnp-3317	165	9	assessed	assess	VERB
fnp-3317	165	10	,	,	PUNCT
fnp-3317	165	11	they	they	PRON
fnp-3317	165	12	surprisingly	surprisingly	ADV
fnp-3317	165	13	found	find	VERB
fnp-3317	165	14	that	that	SCONJ
fnp-3317	165	15	these	these	DET
fnp-3317	165	16	pathways	pathway	NOUN
fnp-3317	165	17	were	be	AUX
fnp-3317	165	18	not	not	PART
fnp-3317	165	19	responsible	responsible	ADJ
fnp-3317	165	20	.	.	PUNCT
fnp-3317	166	1	remarkably	remarkably	ADV
fnp-3317	166	2	,	,	PUNCT
fnp-3317	166	3	they	they	PRON
fnp-3317	166	4	found	find	VERB
fnp-3317	166	5	igf2	igf2	PROPN
fnp-3317	166	6	signaling	signal	VERB
fnp-3317	166	7	enhanced	enhanced	ADJ
fnp-3317	166	8	secretion	secretion	NOUN
fnp-3317	166	9	of	of	ADP
fnp-3317	166	10	soluble	soluble	ADJ
fnp-3317	166	11	mutant	mutant	NOUN
fnp-3317	166	12	huntingtin	huntingtin	NOUN
fnp-3317	166	13	into	into	ADP
fnp-3317	166	14	exosomes	exosome	NOUN
fnp-3317	166	15	/	/	SYM
fnp-3317	166	16	microvesicles	microvesicle	NOUN
fnp-3317	166	17	.	.	PUNCT
fnp-3317	167	1	these	these	DET
fnp-3317	167	2	findings	finding	NOUN
fnp-3317	167	3	were	be	AUX
fnp-3317	167	4	not	not	PART
fnp-3317	167	5	limited	limit	VERB
fnp-3317	167	6	to	to	ADP
fnp-3317	167	7	cell	cell	NOUN
fnp-3317	167	8	culture	culture	NOUN
fnp-3317	167	9	but	but	CCONJ
fnp-3317	167	10	were	be	AUX
fnp-3317	167	11	recapitulated	recapitulate	VERB
fnp-3317	167	12	when	when	SCONJ
fnp-3317	167	13	igf2	igf2	PROPN
fnp-3317	167	14	was	be	AUX
fnp-3317	167	15	infused	infuse	VERB
fnp-3317	167	16	into	into	ADP
fnp-3317	167	17	the	the	DET
fnp-3317	167	18	brain	brain	NOUN
fnp-3317	167	19	of	of	ADP
fnp-3317	167	20	hd	hd	NOUN
fnp-3317	167	21	mice	mouse	NOUN
fnp-3317	167	22	.	.	PUNCT
fnp-3317	168	1	finally	finally	ADV
fnp-3317	168	2	,	,	PUNCT
fnp-3317	168	3	these	these	DET
fnp-3317	168	4	findings	finding	NOUN
fnp-3317	168	5	were	be	AUX
fnp-3317	168	6	validated	validate	VERB
fnp-3317	168	7	in	in	ADP
fnp-3317	168	8	human	human	ADJ
fnp-3317	168	9	tissue	tissue	NOUN
fnp-3317	168	10	samples	sample	NOUN
fnp-3317	168	11	,	,	PUNCT
fnp-3317	168	12	with	with	ADP
fnp-3317	168	13	a	a	DET
fnp-3317	168	14	reduction	reduction	NOUN
fnp-3317	168	15	in	in	ADP
fnp-3317	168	16	igf2	igf2	PROPN
fnp-3317	168	17	in	in	ADP
fnp-3317	168	18	post	post	ADJ
fnp-3317	168	19	-	-	ADJ
fnp-3317	168	20	mortem	mortem	ADJ
fnp-3317	168	21	hd	hd	NOUN
fnp-3317	168	22	brain	brain	NOUN
fnp-3317	168	23	and	and	CCONJ
fnp-3317	168	24	blood	blood	NOUN
fnp-3317	168	25	.	.	PUNCT
fnp-3317	169	1	these	these	DET
fnp-3317	169	2	findings	finding	NOUN
fnp-3317	169	3	take	take	VERB
fnp-3317	169	4	us	we	PRON
fnp-3317	169	5	one	one	NUM
fnp-3317	169	6	step	step	NOUN
fnp-3317	169	7	closer	close	ADV
fnp-3317	169	8	to	to	ADP
fnp-3317	169	9	understanding	understand	VERB
fnp-3317	169	10	the	the	DET
fnp-3317	169	11	role	role	NOUN
fnp-3317	169	12	of	of	ADP
fnp-3317	169	13	the	the	DET
fnp-3317	169	14	upr	upr	NOUN
fnp-3317	169	15	in	in	ADP
fnp-3317	169	16	hd	hd	NOUN
fnp-3317	169	17	and	and	CCONJ
fnp-3317	169	18	suggest	suggest	VERB
fnp-3317	169	19	a	a	DET
fnp-3317	169	20	mechanism	mechanism	NOUN
fnp-3317	169	21	that	that	PRON
fnp-3317	169	22	could	could	AUX
fnp-3317	169	23	be	be	AUX
fnp-3317	169	24	targeted	target	VERB
fnp-3317	169	25	for	for	ADP
fnp-3317	169	26	therapeutics	therapeutic	NOUN
fnp-3317	169	27	.	.	PUNCT
fnp-3317	170	1	10	10	NUM
fnp-3317	170	2	.	.	X
fnp-3317	170	3	chronic	chronic	ADJ
fnp-3317	170	4	traumatic	traumatic	ADJ
fnp-3317	170	5	encephalopathy	encephalopathy	NOUN
fnp-3317	170	6	:	:	PUNCT
fnp-3317	170	7	what	what	PRON
fnp-3317	170	8	about	about	ADP
fnp-3317	170	9	the	the	DET
fnp-3317	170	10	astrocytes	astrocyte	NOUN
fnp-3317	170	11	?	?	PUNCT
fnp-3317	171	1	slightly	slightly	ADV
fnp-3317	171	2	over	over	ADP
fnp-3317	171	3	ten	ten	NUM
fnp-3317	171	4	years	year	NOUN
fnp-3317	171	5	ago	ago	ADV
fnp-3317	171	6	,	,	PUNCT
fnp-3317	171	7	chronic	chronic	ADJ
fnp-3317	171	8	traumatic	traumatic	ADJ
fnp-3317	171	9	encephalopathy	encephalopathy	NOUN
fnp-3317	171	10	(	(	PUNCT
fnp-3317	171	11	cte	cte	NOUN
fnp-3317	171	12	)	)	PUNCT
fnp-3317	171	13	was	be	AUX
fnp-3317	171	14	propelled	propel	VERB
fnp-3317	171	15	to	to	ADP
fnp-3317	171	16	the	the	DET
fnp-3317	171	17	fore	fore	NOUN
fnp-3317	171	18	of	of	ADP
fnp-3317	171	19	neurodegenerative	neurodegenerative	ADJ
fnp-3317	171	20	disease	disease	NOUN
fnp-3317	171	21	research	research	NOUN
fnp-3317	171	22	where	where	SCONJ
fnp-3317	171	23	it	it	PRON
fnp-3317	171	24	has	have	AUX
fnp-3317	171	25	remained	remain	VERB
fnp-3317	171	26	.	.	PUNCT
fnp-3317	172	1	since	since	SCONJ
fnp-3317	172	2	that	that	DET
fnp-3317	172	3	time	time	NOUN
fnp-3317	172	4	,	,	PUNCT
fnp-3317	172	5	broad	broad	ADJ
fnp-3317	172	6	consensus	consensus	NOUN
fnp-3317	172	7	has	have	AUX
fnp-3317	172	8	emerged	emerge	VERB
fnp-3317	172	9	among	among	ADP
fnp-3317	172	10	neuropathologists	neuropathologist	NOUN
fnp-3317	172	11	that	that	SCONJ
fnp-3317	172	12	cte	cte	PROPN
fnp-3317	172	13	has	have	VERB
fnp-3317	172	14	a	a	DET
fnp-3317	172	15	distinct	distinct	ADJ
fnp-3317	172	16	neuropathological	neuropathological	ADJ
fnp-3317	172	17	presentation	presentation	NOUN
fnp-3317	172	18	that	that	PRON
fnp-3317	172	19	is	be	AUX
fnp-3317	172	20	distinguishable	distinguishable	ADJ
fnp-3317	172	21	from	from	ADP
fnp-3317	172	22	other	other	ADJ
fnp-3317	172	23	tauopathies	tauopathie	NOUN
fnp-3317	172	24	,	,	PUNCT
fnp-3317	172	25	with	with	ADP
fnp-3317	172	26	a	a	DET
fnp-3317	172	27	unique	unique	ADJ
fnp-3317	172	28	pathognomonic	pathognomonic	ADJ
fnp-3317	172	29	perivascular	perivascular	ADJ
fnp-3317	172	30	lesion	lesion	NOUN
fnp-3317	172	31	that	that	PRON
fnp-3317	172	32	was	be	AUX
fnp-3317	172	33	codified	codify	VERB
fnp-3317	172	34	in	in	ADP
fnp-3317	172	35	consensus	consensus	NOUN
fnp-3317	172	36	criteria	criterion	NOUN
fnp-3317	172	37	(	(	PUNCT
fnp-3317	172	38	mckee	mckee	NOUN
fnp-3317	172	39	et	et	PROPN
fnp-3317	172	40	al	al	PROPN
fnp-3317	172	41	.	.	PROPN
fnp-3317	172	42	,	,	PUNCT
fnp-3317	172	43	2016	2016	NUM
fnp-3317	172	44	)	)	PUNCT
fnp-3317	172	45	.	.	PUNCT
fnp-3317	173	1	in	in	ADP
fnp-3317	173	2	this	this	DET
fnp-3317	173	3	report	report	NOUN
fnp-3317	173	4	,	,	PUNCT
fnp-3317	173	5	the	the	DET
fnp-3317	173	6	pathognomonic	pathognomonic	ADJ
fnp-3317	173	7	lesion	lesion	NOUN
fnp-3317	173	8	was	be	AUX
fnp-3317	173	9	described	describe	VERB
fnp-3317	173	10	as	as	ADP
fnp-3317	173	11	consisting	consist	VERB
fnp-3317	173	12	of	of	ADP
fnp-3317	173	13	“	"	PUNCT
fnp-3317	173	14	p	p	PROPN
fnp-3317	173	15	-	-	PUNCT
fnp-3317	173	16	tau	tau	NOUN
fnp-3317	173	17	aggregates	aggregate	NOUN
fnp-3317	173	18	in	in	ADP
fnp-3317	173	19	neurons	neuron	NOUN
fnp-3317	173	20	,	,	PUNCT
fnp-3317	173	21	astrocytes	astrocyte	NOUN
fnp-3317	173	22	,	,	PUNCT
fnp-3317	173	23	and	and	CCONJ
fnp-3317	173	24	cell	cell	NOUN
fnp-3317	173	25	processes	process	NOUN
fnp-3317	173	26	around	around	ADP
fnp-3317	173	27	small	small	ADJ
fnp-3317	173	28	vessels	vessel	NOUN
fnp-3317	173	29	in	in	ADP
fnp-3317	173	30	an	an	DET
fnp-3317	173	31	irregular	irregular	ADJ
fnp-3317	173	32	pattern	pattern	NOUN
fnp-3317	173	33	at	at	ADP
fnp-3317	173	34	the	the	DET
fnp-3317	173	35	depths	depth	NOUN
fnp-3317	173	36	of	of	ADP
fnp-3317	173	37	the	the	DET
fnp-3317	173	38	cortical	cortical	ADJ
fnp-3317	173	39	sulci	sulci	NOUN
fnp-3317	173	40	”	"	PUNCT
fnp-3317	173	41	.	.	PUNCT
fnp-3317	174	1	while	while	SCONJ
fnp-3317	174	2	this	this	DET
fnp-3317	174	3	working	work	VERB
fnp-3317	174	4	definition	definition	NOUN
fnp-3317	174	5	was	be	AUX
fnp-3317	174	6	considered	consider	VERB
fnp-3317	174	7	sufficiently	sufficiently	ADV
fnp-3317	174	8	precise	precise	ADJ
fnp-3317	174	9	,	,	PUNCT
fnp-3317	174	10	confusion	confusion	NOUN
fnp-3317	174	11	emerged	emerge	VERB
fnp-3317	174	12	and	and	CCONJ
fnp-3317	174	13	persisted	persist	VERB
fnp-3317	174	14	in	in	ADP
fnp-3317	174	15	the	the	DET
fnp-3317	174	16	literature	literature	NOUN
fnp-3317	174	17	around	around	ADP
fnp-3317	174	18	the	the	DET
fnp-3317	174	19	perivascular	perivascular	ADJ
fnp-3317	174	20	astrocytes	astrocyte	NOUN
fnp-3317	174	21	in	in	ADP
fnp-3317	174	22	aging	age	VERB
fnp-3317	174	23	related	relate	VERB
fnp-3317	174	24	tau	tau	PROPN
fnp-3317	174	25	astrogliopathy	astrogliopathy	ADJ
fnp-3317	174	26	(	(	PUNCT
fnp-3317	174	27	artag	artag	ADJ
fnp-3317	174	28	)	)	PUNCT
fnp-3317	174	29	(	(	PUNCT
fnp-3317	174	30	kovacs	kovacs	PROPN
fnp-3317	174	31	et	et	PROPN
fnp-3317	174	32	al	al	PROPN
fnp-3317	174	33	.	.	PROPN
fnp-3317	174	34	,	,	PUNCT
fnp-3317	174	35	2016	2016	NUM
fnp-3317	174	36	)	)	PUNCT
fnp-3317	174	37	that	that	PRON
fnp-3317	174	38	can	can	AUX
fnp-3317	174	39	generally	generally	ADV
fnp-3317	174	40	be	be	AUX
fnp-3317	174	41	differentiated	differentiate	VERB
fnp-3317	174	42	based	base	VERB
fnp-3317	174	43	on	on	ADP
fnp-3317	174	44	the	the	DET
fnp-3317	174	45	absence	absence	NOUN
fnp-3317	174	46	of	of	ADP
fnp-3317	174	47	neurons	neuron	NOUN
fnp-3317	174	48	and	and	CCONJ
fnp-3317	174	49	localization	localization	NOUN
fnp-3317	174	50	in	in	ADP
fnp-3317	174	51	the	the	DET
fnp-3317	174	52	white	white	ADJ
fnp-3317	174	53	matter	matter	NOUN
fnp-3317	174	54	or	or	CCONJ
fnp-3317	174	55	subpial	subpial	ADJ
fnp-3317	174	56	compartments	compartment	NOUN
fnp-3317	174	57	.	.	PUNCT
fnp-3317	175	1	clarification	clarification	NOUN
fnp-3317	175	2	was	be	AUX
fnp-3317	175	3	not	not	PART
fnp-3317	175	4	sufficient	sufficient	ADJ
fnp-3317	175	5	to	to	PART
fnp-3317	175	6	put	put	VERB
fnp-3317	175	7	the	the	DET
fnp-3317	175	8	astrocyte	astrocyte	NOUN
fnp-3317	175	9	question	question	NOUN
fnp-3317	175	10	to	to	PART
fnp-3317	175	11	rest	rest	VERB
fnp-3317	175	12	(	(	PUNCT
fnp-3317	175	13	mckee	mckee	NOUN
fnp-3317	175	14	et	et	PROPN
fnp-3317	175	15	al	al	PROPN
fnp-3317	175	16	.	.	PROPN
fnp-3317	175	17	,	,	PUNCT
fnp-3317	175	18	2020	2020	NUM
fnp-3317	175	19	)	)	PUNCT
fnp-3317	175	20	.	.	PUNCT
fnp-3317	176	1	setting	set	VERB
fnp-3317	176	2	aside	aside	ADV
fnp-3317	176	3	artag	artag	ADJ
fnp-3317	176	4	,	,	PUNCT
fnp-3317	176	5	there	there	PRON
fnp-3317	176	6	is	be	VERB
fnp-3317	176	7	a	a	DET
fnp-3317	176	8	tremendous	tremendous	ADJ
fnp-3317	176	9	burden	burden	NOUN
fnp-3317	176	10	of	of	ADP
fnp-3317	176	11	p	p	PROPN
fnp-3317	176	12	-	-	PUNCT
fnp-3317	176	13	tau	tau	NOUN
fnp-3317	176	14	positive	positive	ADJ
fnp-3317	176	15	gray	gray	ADJ
fnp-3317	176	16	matter	matter	NOUN
fnp-3317	176	17	astrocytes	astrocyte	NOUN
fnp-3317	176	18	in	in	ADP
fnp-3317	176	19	cte	cte	PROPN
fnp-3317	176	20	.	.	PUNCT
fnp-3317	177	1	a	a	DET
fnp-3317	177	2	study	study	NOUN
fnp-3317	177	3	led	lead	VERB
fnp-3317	177	4	by	by	ADP
fnp-3317	177	5	john	john	PROPN
fnp-3317	177	6	trojanowski	trojanowski	PROPN
fnp-3317	177	7	at	at	ADP
fnp-3317	177	8	the	the	DET
fnp-3317	177	9	university	university	PROPN
fnp-3317	177	10	of	of	ADP
fnp-3317	177	11	pennsylvania	pennsylvania	PROPN
fnp-3317	177	12	and	and	CCONJ
fnp-3317	177	13	william	william	PROPN
fnp-3317	177	14	stewart	stewart	PROPN
fnp-3317	177	15	at	at	ADP
fnp-3317	177	16	the	the	DET
fnp-3317	177	17	university	university	PROPN
fnp-3317	177	18	of	of	ADP
fnp-3317	177	19	glasgow	glasgow	PROPN
fnp-3317	177	20	published	publish	VERB
fnp-3317	177	21	in	in	ADP
fnp-3317	177	22	brain	brain	NOUN
fnp-3317	177	23	communications	communication	NOUN
fnp-3317	177	24	sought	seek	VERB
fnp-3317	177	25	to	to	PART
fnp-3317	177	26	neuroanatomically	neuroanatomically	ADV
fnp-3317	177	27	map	map	VERB
fnp-3317	177	28	these	these	DET
fnp-3317	177	29	astrocytes	astrocyte	NOUN
fnp-3317	177	30	and	and	CCONJ
fnp-3317	177	31	found	find	VERB
fnp-3317	177	32	a	a	DET
fnp-3317	177	33	preferential	preferential	ADJ
fnp-3317	177	34	accumulation	accumulation	NOUN
fnp-3317	177	35	in	in	ADP
fnp-3317	177	36	the	the	DET
fnp-3317	177	37	sulcal	sulcal	ADJ
fnp-3317	177	38	depths	depth	NOUN
fnp-3317	177	39	,	,	PUNCT
fnp-3317	177	40	the	the	DET
fnp-3317	177	41	precise	precise	ADJ
fnp-3317	177	42	region	region	NOUN
fnp-3317	177	43	that	that	PRON
fnp-3317	177	44	is	be	AUX
fnp-3317	177	45	biomechanically	biomechanically	ADV
fnp-3317	177	46	vulnerable	vulnerable	ADJ
fnp-3317	177	47	in	in	ADP
fnp-3317	177	48	cte	cte	NOUN
fnp-3317	177	49	and	and	CCONJ
fnp-3317	177	50	where	where	SCONJ
fnp-3317	177	51	tau	tau	PROPN
fnp-3317	177	52	pathology	pathology	NOUN
fnp-3317	177	53	first	first	ADV
fnp-3317	177	54	emerges	emerge	VERB
fnp-3317	177	55	(	(	PUNCT
fnp-3317	177	56	arena	arena	NOUN
fnp-3317	177	57	et	et	PROPN
fnp-3317	177	58	al	al	PROPN
fnp-3317	177	59	.	.	PROPN
fnp-3317	177	60	,	,	PUNCT
fnp-3317	177	61	2020	2020	NUM
fnp-3317	177	62	)	)	PUNCT
fnp-3317	177	63	.	.	PUNCT
fnp-3317	178	1	this	this	PRON
fnp-3317	178	2	is	be	AUX
fnp-3317	178	3	in	in	ADP
fnp-3317	178	4	contrast	contrast	NOUN
fnp-3317	178	5	to	to	ADP
fnp-3317	178	6	neuronal	neuronal	ADJ
fnp-3317	178	7	tau	tau	PROPN
fnp-3317	178	8	pathology	pathology	NOUN
fnp-3317	178	9	which	which	PRON
fnp-3317	178	10	they	they	PRON
fnp-3317	178	11	found	find	VERB
fnp-3317	178	12	was	be	AUX
fnp-3317	178	13	more	more	ADV
fnp-3317	178	14	diffuse	diffuse	ADJ
fnp-3317	178	15	.	.	PUNCT
fnp-3317	179	1	this	this	PRON
fnp-3317	179	2	seems	seem	VERB
fnp-3317	179	3	to	to	PART
fnp-3317	179	4	suggest	suggest	VERB
fnp-3317	179	5	that	that	PRON
fnp-3317	179	6	astrocyte	astrocyte	NOUN
fnp-3317	179	7	pathology	pathology	NOUN
fnp-3317	179	8	is	be	AUX
fnp-3317	179	9	an	an	DET
fnp-3317	179	10	early	early	ADJ
fnp-3317	179	11	event	event	NOUN
fnp-3317	179	12	.	.	PUNCT
fnp-3317	180	1	in	in	ADP
fnp-3317	180	2	another	another	DET
fnp-3317	180	3	study	study	NOUN
fnp-3317	180	4	published	publish	VERB
fnp-3317	180	5	in	in	ADP
fnp-3317	180	6	brain	brain	NOUN
fnp-3317	180	7	pathology	pathology	NOUN
fnp-3317	180	8	led	lead	VERB
fnp-3317	180	9	by	by	ADP
fnp-3317	180	10	ann	ann	PROPN
fnp-3317	180	11	mckee	mckee	PROPN
fnp-3317	180	12	and	and	CCONJ
fnp-3317	180	13	john	john	PROPN
fnp-3317	180	14	crary	crary	PROPN
fnp-3317	180	15	(	(	PUNCT
fnp-3317	180	16	writer	writer	NOUN
fnp-3317	180	17	of	of	ADP
fnp-3317	180	18	this	this	DET
fnp-3317	180	19	review	review	NOUN
fnp-3317	180	20	)	)	PUNCT
fnp-3317	180	21	,	,	PUNCT
fnp-3317	180	22	a	a	DET
fnp-3317	180	23	spectrum	spectrum	NOUN
fnp-3317	180	24	of	of	ADP
fnp-3317	180	25	cases	case	NOUN
fnp-3317	180	26	that	that	PRON
fnp-3317	180	27	also	also	ADV
fnp-3317	180	28	included	include	VERB
fnp-3317	180	29	very	very	ADV
fnp-3317	180	30	early	early	ADJ
fnp-3317	180	31	cte	cte	NOUN
fnp-3317	180	32	lesions	lesion	NOUN
fnp-3317	180	33	was	be	AUX
fnp-3317	180	34	able	able	ADJ
fnp-3317	180	35	to	to	PART
fnp-3317	180	36	pinpoint	pinpoint	VERB
fnp-3317	180	37	abnormal	abnormal	ADJ
fnp-3317	180	38	tau	tau	NOUN
fnp-3317	180	39	in	in	ADP
fnp-3317	180	40	early	early	ADJ
fnp-3317	180	41	pathognomonic	pathognomonic	ADJ
fnp-3317	180	42	lesions	lesion	NOUN
fnp-3317	180	43	to	to	ADP
fnp-3317	180	44	perivascular	perivascular	ADJ
fnp-3317	180	45	neurons	neuron	NOUN
fnp-3317	180	46	(	(	PUNCT
fnp-3317	180	47	figure	figure	NOUN
fnp-3317	180	48	6	6	NUM
fnp-3317	180	49	)	)	PUNCT
fnp-3317	180	50	,	,	PUNCT
fnp-3317	180	51	but	but	CCONJ
fnp-3317	180	52	not	not	PART
fnp-3317	180	53	astrocytes	astrocyte	NOUN
fnp-3317	180	54	,	,	PUNCT
fnp-3317	180	55	which	which	PRON
fnp-3317	180	56	appeared	appear	VERB
fnp-3317	180	57	to	to	PART
fnp-3317	180	58	accumulate	accumulate	VERB
fnp-3317	180	59	later	later	ADV
fnp-3317	180	60	in	in	ADP
fnp-3317	180	61	the	the	DET
fnp-3317	180	62	disease	disease	NOUN
fnp-3317	180	63	progression	progression	NOUN
fnp-3317	180	64	(	(	PUNCT
fnp-3317	180	65	cherry	cherry	NOUN
fnp-3317	180	66	et	et	PROPN
fnp-3317	180	67	al	al	PROPN
fnp-3317	180	68	.	.	PROPN
fnp-3317	180	69	,	,	PUNCT
fnp-3317	180	70	2020	2020	NUM
fnp-3317	180	71	)	)	PUNCT
fnp-3317	180	72	.	.	PUNCT
fnp-3317	181	1	this	this	DET
fnp-3317	181	2	tau	tau	PROPN
fnp-3317	181	3	pathology	pathology	NOUN
fnp-3317	181	4	consisted	consist	VERB
fnp-3317	181	5	predominantly	predominantly	ADV
fnp-3317	181	6	of	of	ADP
fnp-3317	181	7	tau	tau	PROPN
fnp-3317	181	8	isoforms	isoform	NOUN
fnp-3317	181	9	containing	contain	VERB
fnp-3317	181	10	four	four	NUM
fnp-3317	181	11	microtubule	microtubule	NOUN
fnp-3317	181	12	binding	bind	VERB
fnp-3317	181	13	domain	domain	NOUN
fnp-3317	181	14	repeats	repeat	NOUN
fnp-3317	181	15	(	(	PUNCT
fnp-3317	181	16	4r	4r	NUM
fnp-3317	181	17	tau	tau	NOUN
fnp-3317	181	18	)	)	PUNCT
fnp-3317	181	19	,	,	PUNCT
fnp-3317	181	20	an	an	DET
fnp-3317	181	21	isoform	isoform	NOUN
fnp-3317	181	22	that	that	PRON
fnp-3317	181	23	has	have	AUX
fnp-3317	181	24	been	be	AUX
fnp-3317	181	25	proposed	propose	VERB
fnp-3317	181	26	to	to	PART
fnp-3317	181	27	be	be	AUX
fnp-3317	181	28	especially	especially	ADV
fnp-3317	181	29	toxic	toxic	ADJ
fnp-3317	181	30	given	give	VERB
fnp-3317	181	31	its	its	PRON
fnp-3317	181	32	increased	increase	VERB
fnp-3317	181	33	propensity	propensity	NOUN
fnp-3317	181	34	towards	towards	ADP
fnp-3317	181	35	aggregation	aggregation	NOUN
fnp-3317	181	36	.	.	PUNCT
fnp-3317	182	1	together	together	ADV
fnp-3317	182	2	,	,	PUNCT
fnp-3317	182	3	these	these	DET
fnp-3317	182	4	findings	finding	NOUN
fnp-3317	182	5	point	point	VERB
fnp-3317	182	6	to	to	ADP
fnp-3317	182	7	a	a	DET
fnp-3317	182	8	complex	complex	ADJ
fnp-3317	182	9	picture	picture	NOUN
fnp-3317	182	10	of	of	ADP
fnp-3317	182	11	evolving	evolve	VERB
fnp-3317	182	12	tau	tau	PROPN
fnp-3317	182	13	pathology	pathology	NOUN
fnp-3317	182	14	in	in	ADP
fnp-3317	182	15	neurons	neuron	NOUN
fnp-3317	182	16	and	and	CCONJ
fnp-3317	182	17	astrocytes	astrocyte	NOUN
fnp-3317	182	18	early	early	ADV
fnp-3317	182	19	in	in	ADP
fnp-3317	182	20	cte	cte	NOUN
fnp-3317	182	21	and	and	CCONJ
fnp-3317	182	22	we	we	PRON
fnp-3317	182	23	expect	expect	VERB
fnp-3317	182	24	that	that	DET
fnp-3317	182	25	research	research	NOUN
fnp-3317	182	26	in	in	ADP
fnp-3317	182	27	the	the	DET
fnp-3317	182	28	coming	come	VERB
fnp-3317	182	29	years	year	NOUN
fnp-3317	182	30	around	around	ADP
fnp-3317	182	31	the	the	DET
fnp-3317	182	32	role	role	NOUN
fnp-3317	182	33	of	of	ADP
fnp-3317	182	34	astrocytes	astrocyte	NOUN
fnp-3317	182	35	in	in	ADP
fnp-3317	182	36	early	early	ADJ
fnp-3317	182	37	cte	cte	NOUN
fnp-3317	182	38	will	will	AUX
fnp-3317	182	39	intensify	intensify	VERB
fnp-3317	182	40	.	.	PUNCT
fnp-3317	183	1	figure	figure	VERB
fnp-3317	183	2	6	6	NUM
fnp-3317	183	3	.	.	PUNCT
fnp-3317	183	4	immunofluorescence	immunofluorescence	NOUN
fnp-3317	183	5	microscopy	microscopy	NOUN
fnp-3317	183	6	in	in	ADP
fnp-3317	183	7	a	a	DET
fnp-3317	183	8	sulcal	sulcal	ADJ
fnp-3317	183	9	region	region	NOUN
fnp-3317	183	10	from	from	ADP
fnp-3317	183	11	an	an	DET
fnp-3317	183	12	individual	individual	NOUN
fnp-3317	183	13	who	who	PRON
fnp-3317	183	14	passed	pass	VERB
fnp-3317	183	15	away	away	ADV
fnp-3317	183	16	in	in	ADP
fnp-3317	183	17	their	their	PRON
fnp-3317	183	18	20s	20	NOUN
fnp-3317	183	19	with	with	ADP
fnp-3317	183	20	chronic	chronic	ADJ
fnp-3317	183	21	traumatic	traumatic	ADJ
fnp-3317	183	22	encephalopathy	encephalopathy	NOUN
fnp-3317	183	23	(	(	PUNCT
fnp-3317	183	24	cte	cte	NOUN
fnp-3317	183	25	)	)	PUNCT
fnp-3317	183	26	.	.	PUNCT
fnp-3317	184	1	a.	a.	PROPN
fnp-3317	184	2	low	low	PROPN
fnp-3317	184	3	power	power	NOUN
fnp-3317	184	4	image	image	NOUN
fnp-3317	184	5	highlighting	highlight	VERB
fnp-3317	184	6	two	two	NUM
fnp-3317	184	7	perivascular	perivascular	ADJ
fnp-3317	184	8	lesions	lesion	NOUN
fnp-3317	184	9	.	.	PUNCT
fnp-3317	185	1	b.	b.	PROPN
fnp-3317	185	2	high	high	ADJ
fnp-3317	185	3	power	power	NOUN
fnp-3317	185	4	image	image	NOUN
fnp-3317	185	5	showing	show	VERB
fnp-3317	185	6	staining	stain	VERB
fnp-3317	185	7	with	with	ADP
fnp-3317	185	8	markers	marker	NOUN
fnp-3317	185	9	for	for	ADP
fnp-3317	185	10	astroglia	astroglia	PROPN
fnp-3317	185	11	(	(	PUNCT
fnp-3317	185	12	gfap	gfap	ADJ
fnp-3317	185	13	,	,	PUNCT
fnp-3317	185	14	blue	blue	ADJ
fnp-3317	185	15	)	)	PUNCT
fnp-3317	185	16	,	,	PUNCT
fnp-3317	185	17	neurons	neuron	NOUN
fnp-3317	185	18	(	(	PUNCT
fnp-3317	185	19	map2	map2	PROPN
fnp-3317	185	20	,	,	PUNCT
fnp-3317	185	21	green	green	ADJ
fnp-3317	185	22	)	)	PUNCT
fnp-3317	185	23	and	and	CCONJ
fnp-3317	185	24	abnormal	abnormal	ADJ
fnp-3317	185	25	hyperphosphorylated	hyperphosphorylate	VERB
fnp-3317	185	26	p	p	PROPN
fnp-3317	185	27	-	-	PUNCT
fnp-3317	185	28	tau	tau	PROPN
fnp-3317	185	29	(	(	PUNCT
fnp-3317	185	30	at8	at8	PROPN
fnp-3317	185	31	;	;	PUNCT
fnp-3317	185	32	green	green	ADJ
fnp-3317	185	33	)	)	PUNCT
fnp-3317	185	34	.	.	PUNCT
fnp-3317	186	1	white	white	PROPN
fnp-3317	186	2	arrows	arrow	NOUN
fnp-3317	186	3	mark	mark	PROPN
fnp-3317	186	4	colocalization	colocalization	NOUN
fnp-3317	186	5	.	.	PUNCT
fnp-3317	187	1	in	in	ADP
fnp-3317	187	2	these	these	DET
fnp-3317	187	3	lesions	lesion	NOUN
fnp-3317	187	4	,	,	PUNCT
fnp-3317	187	5	there	there	PRON
fnp-3317	187	6	is	be	VERB
fnp-3317	187	7	only	only	ADJ
fnp-3317	187	8	map2	map2	ADJ
fnp-3317	187	9	overlap	overlap	NOUN
fnp-3317	187	10	with	with	ADP
fnp-3317	187	11	p	p	PROPN
fnp-3317	187	12	-	-	PUNCT
fnp-3317	187	13	tau	tau	NOUN
fnp-3317	187	14	.	.	PUNCT
fnp-3317	188	1	no	no	DET
fnp-3317	188	2	gfap	gfap	PROPN
fnp-3317	188	3	/	/	SYM
fnp-3317	188	4	at8	at8	PROPN
fnp-3317	188	5	colocalization	colocalization	NOUN
fnp-3317	188	6	was	be	AUX
fnp-3317	188	7	seen	see	VERB
fnp-3317	188	8	in	in	ADP
fnp-3317	188	9	this	this	DET
fnp-3317	188	10	case	case	NOUN
fnp-3317	188	11	.	.	PUNCT
fnp-3317	189	1	scale	scale	NOUN
fnp-3317	189	2	bar	bar	NOUN
fnp-3317	189	3	is	be	AUX
fnp-3317	189	4	50	50	NUM
fnp-3317	189	5	um	um	INTJ
fnp-3317	189	6	.	.	PUNCT
fnp-3317	189	7	images	image	NOUN
fnp-3317	189	8	courtesy	courtesy	NOUN
fnp-3317	189	9	of	of	ADP
fnp-3317	189	10	dr	dr	PROPN
fnp-3317	189	11	.	.	PROPN
fnp-3317	189	12	jonathan	jonathan	PROPN
fnp-3317	189	13	cherry	cherry	PROPN
fnp-3317	189	14	and	and	CCONJ
fnp-3317	189	15	ann	ann	PROPN
fnp-3317	189	16	mckee	mckee	PROPN
fnp-3317	189	17	(	(	PUNCT
fnp-3317	189	18	boston	boston	PROPN
fnp-3317	189	19	university	university	PROPN
fnp-3317	189	20	and	and	CCONJ
fnp-3317	189	21	boston	boston	PROPN
fnp-3317	189	22	va	va	PROPN
fnp-3317	189	23	)	)	PUNCT
fnp-3317	189	24	.	.	PUNCT
fnp-3317	190	1	acknowledgement	acknowledgement	PROPN
fnp-3317	190	2	dr	dr	PROPN
fnp-3317	190	3	.	.	PROPN
fnp-3317	190	4	crary	crary	PROPN
fnp-3317	190	5	receives	receive	VERB
fnp-3317	190	6	research	research	NOUN
fnp-3317	190	7	funding	funding	NOUN
fnp-3317	190	8	from	from	ADP
fnp-3317	190	9	the	the	DET
fnp-3317	190	10	nih	nih	PROPN
fnp-3317	190	11	(	(	PUNCT
fnp-3317	190	12	p30ag066514	p30ag066514	NOUN
fnp-3317	190	13	,	,	PUNCT
fnp-3317	190	14	r01ag054008	r01ag054008	NOUN
fnp-3317	190	15	,	,	PUNCT
fnp-3317	190	16	r01ns095252	r01ns095252	NOUN
fnp-3317	190	17	,	,	PUNCT
fnp-3317	190	18	r01ag062348	r01ag062348	NOUN
fnp-3317	190	19	,	,	PUNCT
fnp-3317	190	20	r01ns086736	r01ns086736	NOUN
fnp-3317	190	21	,	,	PUNCT
fnp-3317	190	22	u54ns115266	u54ns115266	PROPN
fnp-3317	190	23	,	,	PUNCT
fnp-3317	190	24	u54ns115322	u54ns115322	NOUN
fnp-3317	190	25	)	)	PUNCT
fnp-3317	190	26	.	.	PUNCT
fnp-3317	191	1	we	we	PRON
fnp-3317	191	2	further	far	ADV
fnp-3317	191	3	acknowledge	acknowledge	VERB
fnp-3317	191	4	the	the	DET
fnp-3317	191	5	rainwater	rainwater	NOUN
fnp-3317	191	6	charitable	charitable	PROPN
fnp-3317	191	7	trust	trust	PROPN
fnp-3317	191	8	/	/	SYM
fnp-3317	191	9	tau	tau	PROPN
fnp-3317	191	10	consortium	consortium	PROPN
fnp-3317	191	11	,	,	PUNCT
fnp-3317	191	12	david	david	PROPN
fnp-3317	191	13	and	and	CCONJ
fnp-3317	191	14	elsie	elsie	PROPN
fnp-3317	191	15	werber	werber	PROPN
fnp-3317	191	16	,	,	PUNCT
fnp-3317	191	17	alexander	alexander	PROPN
fnp-3317	191	18	saint	saint	PROPN
fnp-3317	191	19	amand	amand	PROPN
fnp-3317	191	20	scholar	scholar	PROPN
fnp-3317	191	21	award	award	PROPN
fnp-3317	191	22	and	and	CCONJ
fnp-3317	191	23	karen	karen	PROPN
fnp-3317	191	24	strauss	strauss	PROPN
fnp-3317	191	25	cook	cook	PROPN
fnp-3317	191	26	research	research	NOUN
fnp-3317	191	27	scholar	scholar	NOUN
fnp-3317	191	28	award	award	NOUN
fnp-3317	191	29	.	.	PUNCT
fnp-3317	192	1	references	reference	NOUN
fnp-3317	192	2	arakhamia	arakhamia	VERB
fnp-3317	192	3	,	,	PUNCT
fnp-3317	192	4	t.	t.	PROPN
fnp-3317	192	5	,	,	PUNCT
fnp-3317	192	6	lee	lee	PROPN
fnp-3317	192	7	,	,	PUNCT
fnp-3317	192	8	c.	c.	PROPN
fnp-3317	192	9	e.	e.	PROPN
fnp-3317	192	10	,	,	PUNCT
fnp-3317	192	11	carlomagno	carlomagno	NOUN
fnp-3317	192	12	,	,	PUNCT
fnp-3317	192	13	y.	y.	PROPN
fnp-3317	192	14	,	,	PUNCT
fnp-3317	192	15	duong	duong	PROPN
fnp-3317	192	16	,	,	PUNCT
fnp-3317	192	17	d.	d.	PROPN
fnp-3317	192	18	m.	m.	PROPN
fnp-3317	192	19	,	,	PUNCT
fnp-3317	192	20	kundinger	kundinger	PROPN
fnp-3317	192	21	,	,	PUNCT
fnp-3317	192	22	s.	s.	PROPN
fnp-3317	192	23	r.	r.	PROPN
fnp-3317	192	24	,	,	PUNCT
fnp-3317	192	25	wang	wang	PROPN
fnp-3317	192	26	,	,	PUNCT
fnp-3317	192	27	k.	k.	PROPN
fnp-3317	192	28	,	,	PUNCT
fnp-3317	192	29	williams	williams	PROPN
fnp-3317	192	30	,	,	PUNCT
fnp-3317	192	31	d.	d.	PROPN
fnp-3317	192	32	,	,	PUNCT
fnp-3317	192	33	deture	deture	NOUN
fnp-3317	192	34	,	,	PUNCT
fnp-3317	192	35	m.	m.	NOUN
fnp-3317	192	36	,	,	PUNCT
fnp-3317	192	37	dickson	dickson	PROPN
fnp-3317	192	38	,	,	PUNCT
fnp-3317	192	39	d.	d.	PROPN
fnp-3317	192	40	w.	w.	PROPN
fnp-3317	192	41	,	,	PUNCT
fnp-3317	192	42	cook	cook	VERB
fnp-3317	192	43	,	,	PUNCT
fnp-3317	192	44	c.	c.	PROPN
fnp-3317	192	45	n.	n.	PROPN
fnp-3317	192	46	,	,	PUNCT
fnp-3317	192	47	seyfried	seyfrie	VERB
fnp-3317	192	48	,	,	PUNCT
fnp-3317	192	49	n.	n.	PROPN
fnp-3317	192	50	t.	t.	PROPN
fnp-3317	192	51	,	,	PUNCT
fnp-3317	192	52	petrucelli	petrucelli	PROPN
fnp-3317	192	53	,	,	PUNCT
fnp-3317	192	54	l.	l.	PROPN
fnp-3317	192	55	,	,	PUNCT
fnp-3317	192	56	&	&	CCONJ
fnp-3317	192	57	fitzpatrick	fitzpatrick	PROPN
fnp-3317	192	58	,	,	PUNCT
fnp-3317	193	1	a.	a.	PROPN
fnp-3317	193	2	w.	w.	PROPN
fnp-3317	193	3	p.	p.	PROPN
fnp-3317	193	4	(	(	PUNCT
fnp-3317	193	5	2020	2020	NUM
fnp-3317	193	6	)	)	PUNCT
fnp-3317	193	7	.	.	PUNCT
fnp-3317	194	1	posttranslational	posttranslational	ADJ
fnp-3317	194	2	modifications	modification	NOUN
fnp-3317	194	3	mediate	mediate	VERB
fnp-3317	194	4	the	the	DET
fnp-3317	194	5	structural	structural	ADJ
fnp-3317	194	6	diversity	diversity	NOUN
fnp-3317	194	7	of	of	ADP
fnp-3317	194	8	tauopathy	tauopathy	ADJ
fnp-3317	194	9	strains	strain	NOUN
fnp-3317	194	10	.	.	PUNCT
fnp-3317	195	1	cell	cell	NOUN
fnp-3317	195	2	,	,	PUNCT
fnp-3317	195	3	180(4	180(4	NUM
fnp-3317	195	4	)	)	PUNCT
fnp-3317	195	5	,	,	PUNCT
fnp-3317	195	6	633	633	NUM
fnp-3317	195	7	-	-	PUNCT
fnp-3317	195	8	644.e12	644.e12	PROPN
fnp-3317	195	9	.	.	PUNCT
fnp-3317	196	1	https://doi.org/10.1016/j.cell.2020.01.027	https://doi.org/10.1016/j.cell.2020.01.027	NUM
fnp-3317	196	2	arena	arena	NOUN
fnp-3317	196	3	,	,	PUNCT
fnp-3317	196	4	j.	j.	PROPN
fnp-3317	196	5	d.	d.	PROPN
fnp-3317	196	6	,	,	PUNCT
fnp-3317	196	7	johnson	johnson	PROPN
fnp-3317	196	8	,	,	PUNCT
fnp-3317	196	9	v.	v.	PROPN
fnp-3317	196	10	e.	e.	PROPN
fnp-3317	196	11	,	,	PUNCT
fnp-3317	196	12	lee	lee	PROPN
fnp-3317	196	13	,	,	PUNCT
fnp-3317	196	14	e.	e.	PROPN
fnp-3317	196	15	b.	b.	PROPN
fnp-3317	196	16	,	,	PUNCT
fnp-3317	196	17	gibbons	gibbon	NOUN
fnp-3317	196	18	,	,	PUNCT
fnp-3317	196	19	g.	g.	PROPN
fnp-3317	196	20	s.	s.	PROPN
fnp-3317	196	21	,	,	PUNCT
fnp-3317	196	22	smith	smith	PROPN
fnp-3317	196	23	,	,	PUNCT
fnp-3317	196	24	d.	d.	PROPN
fnp-3317	196	25	h.	h.	PROPN
fnp-3317	196	26	,	,	PUNCT
fnp-3317	196	27	trojanowski	trojanowski	PROPN
fnp-3317	196	28	,	,	PUNCT
fnp-3317	196	29	j.	j.	PROPN
fnp-3317	196	30	q.	q.	PROPN
fnp-3317	196	31	,	,	PUNCT
fnp-3317	196	32	&	&	CCONJ
fnp-3317	196	33	stewart	stewart	PROPN
fnp-3317	196	34	,	,	PUNCT
fnp-3317	196	35	w.	w.	PROPN
fnp-3317	196	36	(	(	PUNCT
fnp-3317	196	37	2020	2020	NUM
fnp-3317	196	38	)	)	PUNCT
fnp-3317	196	39	.	.	PUNCT
fnp-3317	197	1	astroglial	astroglial	ADJ
fnp-3317	197	2	tau	tau	PROPN
fnp-3317	197	3	pathology	pathology	NOUN
fnp-3317	197	4	alone	alone	ADV
fnp-3317	197	5	preferentially	preferentially	ADV
fnp-3317	197	6	concentrates	concentrate	VERB
fnp-3317	197	7	at	at	ADP
fnp-3317	197	8	sulcal	sulcal	ADJ
fnp-3317	197	9	depths	depth	NOUN
fnp-3317	197	10	in	in	ADP
fnp-3317	197	11	chronic	chronic	ADJ
fnp-3317	197	12	traumatic	traumatic	ADJ
fnp-3317	197	13	encephalopathy	encephalopathy	ADJ
fnp-3317	197	14	neuropathologic	neuropathologic	ADJ
fnp-3317	197	15	change	change	NOUN
fnp-3317	197	16	.	.	PUNCT
fnp-3317	198	1	brain	brain	NOUN
fnp-3317	198	2	communications	communication	NOUN
fnp-3317	198	3	,	,	PUNCT
fnp-3317	198	4	2(2	2(2	NUM
fnp-3317	198	5	)	)	PUNCT
fnp-3317	198	6	,	,	PUNCT
fnp-3317	198	7	fcaa210	fcaa210	PROPN
fnp-3317	198	8	.	.	PUNCT
fnp-3317	199	1	https://doi.org/10.1093/braincomms/fcaa210	https://doi.org/10.1093/braincomms/fcaa210	PROPN
fnp-3317	199	2	ashton	ashton	PROPN
fnp-3317	199	3	,	,	PUNCT
fnp-3317	199	4	n.	n.	PROPN
fnp-3317	199	5	j.	j.	PROPN
fnp-3317	199	6	,	,	PUNCT
fnp-3317	199	7	pascoal	pascoal	PROPN
fnp-3317	199	8	,	,	PUNCT
fnp-3317	199	9	t.	t.	PROPN
fnp-3317	199	10	a.	a.	PROPN
fnp-3317	199	11	,	,	PUNCT
fnp-3317	199	12	karikari	karikari	NOUN
fnp-3317	199	13	,	,	PUNCT
fnp-3317	199	14	t.	t.	PROPN
fnp-3317	199	15	k.	k.	PROPN
fnp-3317	199	16	,	,	PUNCT
fnp-3317	199	17	benedet	benedet	PROPN
fnp-3317	199	18	,	,	PUNCT
fnp-3317	199	19	a.	a.	PROPN
fnp-3317	199	20	l.	l.	PROPN
fnp-3317	199	21	,	,	PUNCT
fnp-3317	199	22	lantero	lantero	NOUN
fnp-3317	199	23	-	-	PUNCT
fnp-3317	199	24	rodriguez	rodriguez	NOUN
fnp-3317	199	25	,	,	PUNCT
fnp-3317	199	26	j.	j.	PROPN
fnp-3317	199	27	,	,	PUNCT
fnp-3317	199	28	brinkmalm	brinkmalm	PROPN
fnp-3317	199	29	,	,	PUNCT
fnp-3317	199	30	g.	g.	PROPN
fnp-3317	199	31	,	,	PUNCT
fnp-3317	199	32	snellman	snellman	NOUN
fnp-3317	199	33	,	,	PUNCT
fnp-3317	199	34	a.	a.	NOUN
fnp-3317	199	35	,	,	PUNCT
fnp-3317	199	36	schöll	schöll	NOUN
fnp-3317	199	37	,	,	PUNCT
fnp-3317	199	38	m.	m.	NOUN
fnp-3317	199	39	,	,	PUNCT
fnp-3317	199	40	troakes	troake	NOUN
fnp-3317	199	41	,	,	PUNCT
fnp-3317	199	42	c.	c.	PROPN
fnp-3317	199	43	,	,	PUNCT
fnp-3317	199	44	hye	hye	PROPN
fnp-3317	199	45	,	,	PUNCT
fnp-3317	199	46	a.	a.	PROPN
fnp-3317	199	47	,	,	PUNCT
fnp-3317	199	48	gauthier	gauthier	PROPN
fnp-3317	199	49	,	,	PUNCT
fnp-3317	199	50	s.	s.	PROPN
fnp-3317	199	51	,	,	PUNCT
fnp-3317	199	52	vanmechelen	vanmechelen	VERB
fnp-3317	199	53	,	,	PUNCT
fnp-3317	199	54	e.	e.	PROPN
fnp-3317	199	55	,	,	PUNCT
fnp-3317	199	56	zetterberg	zetterberg	PROPN
fnp-3317	199	57	,	,	PUNCT
fnp-3317	199	58	h.	h.	PROPN
fnp-3317	199	59	,	,	PUNCT
fnp-3317	199	60	rosa	rosa	PROPN
fnp-3317	199	61	-	-	PUNCT
fnp-3317	199	62	neto	neto	PROPN
fnp-3317	199	63	,	,	PUNCT
fnp-3317	199	64	p.	p.	NOUN
fnp-3317	199	65	,	,	PUNCT
fnp-3317	199	66	&	&	CCONJ
fnp-3317	199	67	blennow	blennow	ADV
fnp-3317	199	68	,	,	PUNCT
fnp-3317	199	69	k.	k.	PROPN
fnp-3317	199	70	(	(	PUNCT
fnp-3317	199	71	2021	2021	NUM
fnp-3317	199	72	)	)	PUNCT
fnp-3317	199	73	.	.	PUNCT
fnp-3317	200	1	plasma	plasma	NOUN
fnp-3317	200	2	p	p	PROPN
fnp-3317	200	3	-	-	PUNCT
fnp-3317	200	4	tau231	tau231	PROPN
fnp-3317	200	5	:	:	PUNCT
fnp-3317	200	6	a	a	DET
fnp-3317	200	7	new	new	ADJ
fnp-3317	200	8	biomarker	biomarker	NOUN
fnp-3317	200	9	for	for	ADP
fnp-3317	200	10	incipient	incipient	ADJ
fnp-3317	200	11	alzheimer	alzheimer	PROPN
fnp-3317	200	12	’s	’s	PART
fnp-3317	200	13	disease	disease	PROPN
fnp-3317	200	14	pathology	pathology	PROPN
fnp-3317	200	15	.	.	PUNCT
fnp-3317	201	1	acta	acta	PROPN
fnp-3317	201	2	neuropathologica	neuropathologica	PROPN
fnp-3317	201	3	.	.	PUNCT
fnp-3317	202	1	https://doi.org/10.1007/s00401-021-02275-6	https://doi.org/10.1007/s00401-021-02275-6	PROPN
fnp-3317	202	2	badrfam	badrfam	PROPN
fnp-3317	202	3	,	,	PUNCT
fnp-3317	202	4	r.	r.	PROPN
fnp-3317	202	5	,	,	PUNCT
fnp-3317	202	6	&	&	CCONJ
fnp-3317	202	7	zandifar	zandifar	ADV
fnp-3317	202	8	,	,	PUNCT
fnp-3317	202	9	a.	a.	NOUN
fnp-3317	202	10	(	(	PUNCT
fnp-3317	202	11	2020	2020	NUM
fnp-3317	202	12	)	)	PUNCT
fnp-3317	202	13	.	.	PUNCT
fnp-3317	203	1	from	from	ADP
fnp-3317	203	2	encephalitis	encephalitis	ADJ
fnp-3317	203	3	lethargica	lethargica	NOUN
fnp-3317	203	4	to	to	ADP
fnp-3317	203	5	covid-19	covid-19	PROPN
fnp-3317	203	6	:	:	PUNCT
fnp-3317	203	7	is	be	AUX
fnp-3317	203	8	there	there	PRON
fnp-3317	203	9	another	another	DET
fnp-3317	203	10	epidemic	epidemic	NOUN
fnp-3317	203	11	ahead	ahead	ADV
fnp-3317	203	12	?	?	PUNCT
fnp-3317	204	1	clinical	clinical	ADJ
fnp-3317	204	2	neurology	neurology	NOUN
fnp-3317	204	3	and	and	CCONJ
fnp-3317	204	4	neurosurgery	neurosurgery	NOUN
fnp-3317	204	5	,	,	PUNCT
fnp-3317	204	6	196	196	NUM
fnp-3317	204	7	,	,	PUNCT
fnp-3317	204	8	106065	106065	NUM
fnp-3317	204	9	.	.	PUNCT
fnp-3317	205	1	https://doi.org/10.1016/j.clineuro.2020.106065	https://doi.org/10.1016/j.clineuro.2020.106065	PROPN
fnp-3317	205	2	bryce	bryce	PROPN
fnp-3317	205	3	,	,	PUNCT
fnp-3317	205	4	c.	c.	PROPN
fnp-3317	205	5	,	,	PUNCT
fnp-3317	205	6	grimes	grimes	PROPN
fnp-3317	205	7	,	,	PUNCT
fnp-3317	205	8	z.	z.	PROPN
fnp-3317	205	9	,	,	PUNCT
fnp-3317	205	10	pujadas	pujadas	PROPN
fnp-3317	205	11	,	,	PUNCT
fnp-3317	205	12	e.	e.	PROPN
fnp-3317	205	13	,	,	PUNCT
fnp-3317	205	14	ahuja	ahuja	PROPN
fnp-3317	205	15	,	,	PUNCT
fnp-3317	205	16	s.	s.	PROPN
fnp-3317	205	17	,	,	PUNCT
fnp-3317	205	18	beasley	beasley	PROPN
fnp-3317	205	19	,	,	PUNCT
fnp-3317	205	20	m.	m.	PROPN
fnp-3317	205	21	b.	b.	PROPN
fnp-3317	205	22	,	,	PUNCT
fnp-3317	205	23	albrecht	albrecht	PROPN
fnp-3317	205	24	,	,	PUNCT
fnp-3317	205	25	r.	r.	PROPN
fnp-3317	205	26	,	,	PUNCT
fnp-3317	205	27	hernandez	hernandez	PROPN
fnp-3317	205	28	,	,	PUNCT
fnp-3317	205	29	t.	t.	PROPN
fnp-3317	205	30	,	,	PUNCT
fnp-3317	205	31	stock	stock	NOUN
fnp-3317	205	32	,	,	PUNCT
fnp-3317	205	33	a.	a.	NOUN
fnp-3317	205	34	,	,	PUNCT
fnp-3317	205	35	zhao	zhao	PROPN
fnp-3317	205	36	,	,	PUNCT
fnp-3317	205	37	z.	z.	PROPN
fnp-3317	205	38	,	,	PUNCT
fnp-3317	205	39	rasheed	rasheed	NOUN
fnp-3317	205	40	,	,	PUNCT
fnp-3317	205	41	m.	m.	NOUN
fnp-3317	205	42	a.	a.	PROPN
fnp-3317	205	43	,	,	PUNCT
fnp-3317	205	44	chen	chen	PROPN
fnp-3317	205	45	,	,	PUNCT
fnp-3317	205	46	j.	j.	PROPN
fnp-3317	205	47	,	,	PUNCT
fnp-3317	205	48	li	li	PROPN
fnp-3317	205	49	,	,	PUNCT
fnp-3317	205	50	l.	l.	PROPN
fnp-3317	205	51	,	,	PUNCT
fnp-3317	205	52	wang	wang	PROPN
fnp-3317	205	53	,	,	PUNCT
fnp-3317	205	54	d.	d.	PROPN
fnp-3317	205	55	,	,	PUNCT
fnp-3317	205	56	corben	corben	PROPN
fnp-3317	205	57	,	,	PUNCT
fnp-3317	205	58	a.	a.	NOUN
fnp-3317	205	59	,	,	PUNCT
fnp-3317	205	60	haines	haine	NOUN
fnp-3317	205	61	,	,	PUNCT
fnp-3317	205	62	k.	k.	PROPN
fnp-3317	205	63	,	,	PUNCT
fnp-3317	205	64	westra	westra	PROPN
fnp-3317	205	65	,	,	PUNCT
fnp-3317	205	66	w.	w.	PROPN
fnp-3317	205	67	,	,	PUNCT
fnp-3317	205	68	umphlett	umphlett	PROPN
fnp-3317	205	69	,	,	PUNCT
fnp-3317	205	70	m.	m.	NOUN
fnp-3317	205	71	,	,	PUNCT
fnp-3317	205	72	gordon	gordon	PROPN
fnp-3317	205	73	,	,	PUNCT
fnp-3317	205	74	r.	r.	PROPN
fnp-3317	205	75	e.	e.	PROPN
fnp-3317	205	76	,	,	PUNCT
fnp-3317	205	77	reidy	reidy	PROPN
fnp-3317	205	78	,	,	PUNCT
fnp-3317	205	79	j.	j.	PROPN
fnp-3317	205	80	,	,	PUNCT
fnp-3317	205	81	…	…	PUNCT
fnp-3317	205	82	fowkes	fowke	NOUN
fnp-3317	205	83	,	,	PUNCT
fnp-3317	205	84	m.	m.	NOUN
fnp-3317	205	85	(	(	PUNCT
fnp-3317	205	86	2020	2020	NUM
fnp-3317	205	87	)	)	PUNCT
fnp-3317	205	88	.	.	PUNCT
fnp-3317	206	1	pathophysiology	pathophysiology	NOUN
fnp-3317	206	2	of	of	ADP
fnp-3317	206	3	sars	sar	NOUN
fnp-3317	206	4	-	-	PUNCT
fnp-3317	206	5	cov-2	cov-2	NUM
fnp-3317	206	6	:	:	PUNCT
fnp-3317	206	7	targeting	target	VERB
fnp-3317	206	8	of	of	ADP
fnp-3317	206	9	endothelial	endothelial	ADJ
fnp-3317	206	10	cells	cell	NOUN
fnp-3317	206	11	renders	render	VERB
fnp-3317	206	12	a	a	DET
fnp-3317	206	13	complex	complex	ADJ
fnp-3317	206	14	disease	disease	NOUN
fnp-3317	206	15	with	with	ADP
fnp-3317	206	16	thrombotic	thrombotic	ADJ
fnp-3317	206	17	microangiopathy	microangiopathy	ADJ
fnp-3317	206	18	and	and	CCONJ
fnp-3317	206	19	aberrant	aberrant	ADJ
fnp-3317	206	20	immune	immune	ADJ
fnp-3317	206	21	response	response	NOUN
fnp-3317	206	22	.	.	PUNCT
fnp-3317	207	1	the	the	DET
fnp-3317	207	2	mount	mount	PROPN
fnp-3317	207	3	sinai	sinai	PROPN
fnp-3317	207	4	covid-19	covid-19	PROPN
fnp-3317	207	5	autopsy	autopsy	ADJ
fnp-3317	207	6	experience	experience	NOUN
fnp-3317	207	7	.	.	PUNCT
fnp-3317	208	1	medrxiv	medrxiv	PROPN
fnp-3317	208	2	,	,	PUNCT
fnp-3317	208	3	2020.05.18.20099960	2020.05.18.20099960	PROPN
fnp-3317	208	4	.	.	PUNCT
fnp-3317	209	1	https://doi.org/10.1101/2020.05.18.20099960	https://doi.org/10.1101/2020.05.18.20099960	PROPN
fnp-3317	209	2	cherry	cherry	PROPN
fnp-3317	209	3	,	,	PUNCT
fnp-3317	209	4	j.	j.	PROPN
fnp-3317	209	5	d.	d.	PROPN
fnp-3317	209	6	,	,	PUNCT
fnp-3317	209	7	kim	kim	PROPN
fnp-3317	209	8	,	,	PUNCT
fnp-3317	209	9	s.	s.	PROPN
fnp-3317	209	10	h.	h.	PROPN
fnp-3317	209	11	,	,	PUNCT
fnp-3317	209	12	stein	stein	PROPN
fnp-3317	209	13	,	,	PUNCT
fnp-3317	209	14	t.	t.	PROPN
fnp-3317	209	15	d.	d.	PROPN
fnp-3317	209	16	,	,	PUNCT
fnp-3317	209	17	pothast	pothast	NOUN
fnp-3317	209	18	,	,	PUNCT
fnp-3317	209	19	m.	m.	NOUN
fnp-3317	209	20	j.	j.	PROPN
fnp-3317	209	21	,	,	PUNCT
fnp-3317	209	22	nicks	nick	NOUN
fnp-3317	209	23	,	,	PUNCT
fnp-3317	209	24	r.	r.	PROPN
fnp-3317	209	25	,	,	PUNCT
fnp-3317	209	26	meng	meng	PROPN
fnp-3317	209	27	,	,	PUNCT
fnp-3317	209	28	g.	g.	PROPN
fnp-3317	209	29	,	,	PUNCT
fnp-3317	209	30	huber	huber	PROPN
fnp-3317	209	31	,	,	PUNCT
fnp-3317	209	32	b.	b.	PROPN
fnp-3317	209	33	r.	r.	PROPN
fnp-3317	209	34	,	,	PUNCT
fnp-3317	209	35	mez	mez	PROPN
fnp-3317	209	36	,	,	PUNCT
fnp-3317	209	37	j.	j.	PROPN
fnp-3317	209	38	,	,	PUNCT
fnp-3317	209	39	alosco	alosco	PROPN
fnp-3317	209	40	,	,	PUNCT
fnp-3317	209	41	m.	m.	PROPN
fnp-3317	209	42	l.	l.	PROPN
fnp-3317	209	43	,	,	PUNCT
fnp-3317	209	44	tripodis	tripodi	NOUN
fnp-3317	209	45	,	,	PUNCT
fnp-3317	209	46	y.	y.	PROPN
fnp-3317	209	47	,	,	PUNCT
fnp-3317	209	48	farrell	farrell	PROPN
fnp-3317	209	49	,	,	PUNCT
fnp-3317	209	50	k.	k.	PROPN
fnp-3317	209	51	,	,	PUNCT
fnp-3317	209	52	alvarez	alvarez	PROPN
fnp-3317	209	53	,	,	PUNCT
fnp-3317	209	54	v.	v.	PROPN
fnp-3317	209	55	e.	e.	PROPN
fnp-3317	209	56	,	,	PUNCT
fnp-3317	209	57	mckee	mckee	PROPN
fnp-3317	209	58	,	,	PUNCT
fnp-3317	209	59	a.	a.	PROPN
fnp-3317	209	60	c.	c.	PROPN
fnp-3317	209	61	,	,	PUNCT
fnp-3317	209	62	&	&	CCONJ
fnp-3317	209	63	crary	crary	PROPN
fnp-3317	209	64	,	,	PUNCT
fnp-3317	209	65	j.	j.	PROPN
fnp-3317	209	66	f.	f.	PROPN
fnp-3317	209	67	(	(	PUNCT
fnp-3317	209	68	2020	2020	NUM
fnp-3317	209	69	)	)	PUNCT
fnp-3317	209	70	.	.	PUNCT
fnp-3317	210	1	evolution	evolution	NOUN
fnp-3317	210	2	of	of	ADP
fnp-3317	210	3	neuronal	neuronal	ADJ
fnp-3317	210	4	and	and	CCONJ
fnp-3317	210	5	glial	glial	ADJ
fnp-3317	210	6	tau	tau	PROPN
fnp-3317	210	7	isoforms	isoform	NOUN
fnp-3317	210	8	in	in	ADP
fnp-3317	210	9	chronic	chronic	ADJ
fnp-3317	210	10	traumatic	traumatic	ADJ
fnp-3317	210	11	encephalopathy	encephalopathy	NOUN
fnp-3317	210	12	.	.	PUNCT
fnp-3317	211	1	brain	brain	NOUN
fnp-3317	211	2	pathology	pathology	PROPN
fnp-3317	211	3	(	(	PUNCT
fnp-3317	211	4	zurich	zurich	PROPN
fnp-3317	211	5	,	,	PUNCT
fnp-3317	211	6	switzerland	switzerland	PROPN
fnp-3317	211	7	)	)	PUNCT
fnp-3317	211	8	.	.	PUNCT
fnp-3317	212	1	https://doi.org/10.1111/bpa.12867	https://doi.org/10.1111/bpa.12867	PRON
fnp-3317	212	2	falcon	falcon	PROPN
fnp-3317	212	3	,	,	PUNCT
fnp-3317	212	4	b.	b.	PROPN
fnp-3317	212	5	,	,	PUNCT
fnp-3317	212	6	zhang	zhang	PROPN
fnp-3317	212	7	,	,	PUNCT
fnp-3317	212	8	w.	w.	PROPN
fnp-3317	212	9	,	,	PUNCT
fnp-3317	212	10	murzin	murzin	PROPN
fnp-3317	212	11	,	,	PUNCT
fnp-3317	212	12	a.	a.	NOUN
fnp-3317	212	13	g.	g.	PROPN
fnp-3317	212	14	,	,	PUNCT
fnp-3317	212	15	murshudov	murshudov	PROPN
fnp-3317	212	16	,	,	PUNCT
fnp-3317	212	17	g.	g.	PROPN
fnp-3317	212	18	,	,	PUNCT
fnp-3317	212	19	garringer	garringer	NOUN
fnp-3317	212	20	,	,	PUNCT
fnp-3317	212	21	h.	h.	PROPN
fnp-3317	212	22	j.	j.	PROPN
fnp-3317	212	23	,	,	PUNCT
fnp-3317	212	24	vidal	vidal	PROPN
fnp-3317	212	25	,	,	PUNCT
fnp-3317	212	26	r.	r.	PROPN
fnp-3317	212	27	,	,	PUNCT
fnp-3317	212	28	crowther	crowther	PROPN
fnp-3317	212	29	,	,	PUNCT
fnp-3317	212	30	r.	r.	PROPN
fnp-3317	212	31	a.	a.	PROPN
fnp-3317	212	32	,	,	PUNCT
fnp-3317	212	33	ghetti	ghetti	PROPN
fnp-3317	212	34	,	,	PUNCT
fnp-3317	212	35	b.	b.	PROPN
fnp-3317	212	36	,	,	PUNCT
fnp-3317	212	37	scheres	schere	NOUN
fnp-3317	212	38	,	,	PUNCT
fnp-3317	212	39	s.	s.	PROPN
fnp-3317	212	40	h.	h.	PROPN
fnp-3317	212	41	w.	w.	PROPN
fnp-3317	212	42	,	,	PUNCT
fnp-3317	212	43	&	&	CCONJ
fnp-3317	212	44	goedert	goedert	PROPN
fnp-3317	212	45	,	,	PUNCT
fnp-3317	212	46	m.	m.	NOUN
fnp-3317	212	47	(	(	PUNCT
fnp-3317	212	48	2018	2018	NUM
fnp-3317	212	49	)	)	PUNCT
fnp-3317	212	50	.	.	PUNCT
fnp-3317	213	1	structures	structure	NOUN
fnp-3317	213	2	of	of	ADP
fnp-3317	213	3	filaments	filament	NOUN
fnp-3317	213	4	from	from	ADP
fnp-3317	213	5	pick	pick	NOUN
fnp-3317	213	6	’s	’s	PART
fnp-3317	213	7	disease	disease	NOUN
fnp-3317	213	8	reveal	reveal	VERB
fnp-3317	213	9	a	a	DET
fnp-3317	213	10	novel	novel	NOUN
fnp-3317	213	11	tau	tau	NOUN
fnp-3317	213	12	protein	protein	NOUN
fnp-3317	213	13	fold	fold	NOUN
fnp-3317	213	14	.	.	PUNCT
fnp-3317	214	1	nature	nature	NOUN
fnp-3317	214	2	,	,	PUNCT
fnp-3317	214	3	561(7721	561(7721	NUM
fnp-3317	214	4	)	)	PUNCT
fnp-3317	214	5	,	,	PUNCT
fnp-3317	214	6	137–140	137–140	NUM
fnp-3317	214	7	.	.	PUNCT
fnp-3317	215	1	https://doi.org/10.1038/s41586-018-0454-y	https://doi.org/10.1038/s41586-018-0454-y	PROPN
fnp-3317	215	2	falcon	falcon	PROPN
fnp-3317	215	3	,	,	PUNCT
fnp-3317	215	4	b.	b.	PROPN
fnp-3317	215	5	,	,	PUNCT
fnp-3317	215	6	zivanov	zivanov	PROPN
fnp-3317	215	7	,	,	PUNCT
fnp-3317	215	8	j.	j.	PROPN
fnp-3317	215	9	,	,	PUNCT
fnp-3317	215	10	zhang	zhang	PROPN
fnp-3317	215	11	,	,	PUNCT
fnp-3317	215	12	w.	w.	PROPN
fnp-3317	215	13	,	,	PUNCT
fnp-3317	215	14	murzin	murzin	PROPN
fnp-3317	215	15	,	,	PUNCT
fnp-3317	215	16	a.	a.	NOUN
fnp-3317	215	17	g.	g.	PROPN
fnp-3317	215	18	,	,	PUNCT
fnp-3317	215	19	garringer	garringer	NOUN
fnp-3317	215	20	,	,	PUNCT
fnp-3317	215	21	h.	h.	PROPN
fnp-3317	215	22	j.	j.	PROPN
fnp-3317	215	23	,	,	PUNCT
fnp-3317	215	24	vidal	vidal	PROPN
fnp-3317	215	25	,	,	PUNCT
fnp-3317	215	26	r.	r.	PROPN
fnp-3317	215	27	,	,	PUNCT
fnp-3317	215	28	crowther	crowther	PROPN
fnp-3317	215	29	,	,	PUNCT
fnp-3317	215	30	r.	r.	PROPN
fnp-3317	215	31	a.	a.	PROPN
fnp-3317	215	32	,	,	PUNCT
fnp-3317	215	33	newell	newell	PROPN
fnp-3317	215	34	,	,	PUNCT
fnp-3317	215	35	k.	k.	PROPN
fnp-3317	215	36	l.	l.	PROPN
fnp-3317	215	37	,	,	PUNCT
fnp-3317	215	38	ghetti	ghetti	PROPN
fnp-3317	215	39	,	,	PUNCT
fnp-3317	215	40	b.	b.	PROPN
fnp-3317	215	41	,	,	PUNCT
fnp-3317	215	42	goedert	goedert	PROPN
fnp-3317	215	43	,	,	PUNCT
fnp-3317	215	44	m.	m.	NOUN
fnp-3317	215	45	,	,	PUNCT
fnp-3317	215	46	&	&	CCONJ
fnp-3317	215	47	scheres	schere	NOUN
fnp-3317	215	48	,	,	PUNCT
fnp-3317	215	49	s.	s.	PROPN
fnp-3317	215	50	h.	h.	PROPN
fnp-3317	215	51	w.	w.	PROPN
fnp-3317	215	52	(	(	PUNCT
fnp-3317	215	53	2019	2019	NUM
fnp-3317	215	54	)	)	PUNCT
fnp-3317	215	55	.	.	PUNCT
fnp-3317	216	1	novel	novel	PROPN
fnp-3317	216	2	tau	tau	PROPN
fnp-3317	216	3	filament	filament	NOUN
fnp-3317	216	4	fold	fold	NOUN
fnp-3317	216	5	in	in	ADP
fnp-3317	216	6	chronic	chronic	ADJ
fnp-3317	216	7	traumatic	traumatic	ADJ
fnp-3317	216	8	encephalopathy	encephalopathy	NOUN
fnp-3317	216	9	encloses	enclose	VERB
fnp-3317	216	10	hydrophobic	hydrophobic	NOUN
fnp-3317	216	11	molecules	molecule	NOUN
fnp-3317	216	12	.	.	PUNCT
fnp-3317	217	1	nature	nature	NOUN
fnp-3317	217	2	,	,	PUNCT
fnp-3317	217	3	568(7752	568(7752	NUM
fnp-3317	217	4	)	)	PUNCT
fnp-3317	217	5	,	,	PUNCT
fnp-3317	217	6	420–423	420–423	NUM
fnp-3317	217	7	.	.	PUNCT
fnp-3317	217	8	https://doi.org/10.1038/s41586-019-1026-5	https://doi.org/10.1038/s41586-019-1026-5	PROPN
fnp-3317	217	9	fitzpatrick	fitzpatrick	PROPN
fnp-3317	217	10	,	,	PUNCT
fnp-3317	217	11	a.	a.	PROPN
fnp-3317	217	12	w.	w.	PROPN
fnp-3317	217	13	p.	p.	PROPN
fnp-3317	217	14	,	,	PUNCT
fnp-3317	217	15	falcon	falcon	PROPN
fnp-3317	217	16	,	,	PUNCT
fnp-3317	217	17	b.	b.	PROPN
fnp-3317	217	18	,	,	PUNCT
fnp-3317	217	19	he	he	PRON
fnp-3317	217	20	,	,	PUNCT
fnp-3317	217	21	s.	s.	PROPN
fnp-3317	217	22	,	,	PUNCT
fnp-3317	217	23	murzin	murzin	PROPN
fnp-3317	217	24	,	,	PUNCT
fnp-3317	217	25	a.	a.	NOUN
fnp-3317	217	26	g.	g.	PROPN
fnp-3317	217	27	,	,	PUNCT
fnp-3317	217	28	murshudov	murshudov	PROPN
fnp-3317	217	29	,	,	PUNCT
fnp-3317	217	30	g.	g.	PROPN
fnp-3317	217	31	,	,	PUNCT
fnp-3317	217	32	garringer	garringer	NOUN
fnp-3317	217	33	,	,	PUNCT
fnp-3317	217	34	h.	h.	PROPN
fnp-3317	217	35	j.	j.	PROPN
fnp-3317	217	36	,	,	PUNCT
fnp-3317	217	37	crowther	crowther	PROPN
fnp-3317	217	38	,	,	PUNCT
fnp-3317	217	39	r.	r.	PROPN
fnp-3317	217	40	a.	a.	PROPN
fnp-3317	217	41	,	,	PUNCT
fnp-3317	217	42	ghetti	ghetti	PROPN
fnp-3317	217	43	,	,	PUNCT
fnp-3317	217	44	b.	b.	PROPN
fnp-3317	217	45	,	,	PUNCT
fnp-3317	217	46	goedert	goedert	PROPN
fnp-3317	217	47	,	,	PUNCT
fnp-3317	217	48	m.	m.	NOUN
fnp-3317	217	49	,	,	PUNCT
fnp-3317	217	50	&	&	CCONJ
fnp-3317	217	51	scheres	schere	NOUN
fnp-3317	217	52	,	,	PUNCT
fnp-3317	217	53	s.	s.	PROPN
fnp-3317	217	54	h.	h.	PROPN
fnp-3317	217	55	w.	w.	PROPN
fnp-3317	217	56	(	(	PUNCT
fnp-3317	217	57	2017	2017	NUM
fnp-3317	217	58	)	)	PUNCT
fnp-3317	217	59	.	.	PUNCT
fnp-3317	218	1	cryo	cryo	PROPN
fnp-3317	218	2	-	-	PUNCT
fnp-3317	218	3	em	em	PRON
fnp-3317	218	4	structures	structure	NOUN
fnp-3317	218	5	of	of	ADP
fnp-3317	218	6	tau	tau	PROPN
fnp-3317	218	7	filaments	filament	NOUN
fnp-3317	218	8	from	from	ADP
fnp-3317	218	9	alzheimer	alzheimer	PROPN
fnp-3317	218	10	’s	’s	PART
fnp-3317	218	11	disease	disease	NOUN
fnp-3317	218	12	.	.	PUNCT
fnp-3317	219	1	nature	nature	NOUN
fnp-3317	219	2	,	,	PUNCT
fnp-3317	219	3	547(7662	547(7662	NUM
fnp-3317	219	4	)	)	PUNCT
fnp-3317	219	5	,	,	PUNCT
fnp-3317	219	6	185–190	185–190	NUM
fnp-3317	219	7	.	.	PUNCT
fnp-3317	219	8	https://doi.org/10.1038/nature23002	https://doi.org/10.1038/nature23002	PROPN
fnp-3317	219	9	garcía	garcía	PROPN
fnp-3317	219	10	-	-	PUNCT
fnp-3317	219	11	huerta	huerta	PROPN
fnp-3317	219	12	,	,	PUNCT
fnp-3317	219	13	p.	p.	NOUN
fnp-3317	219	14	,	,	PUNCT
fnp-3317	219	15	troncoso	troncoso	NOUN
fnp-3317	219	16	-	-	PUNCT
fnp-3317	219	17	escudero	escudero	NOUN
fnp-3317	219	18	,	,	PUNCT
fnp-3317	219	19	p.	p.	PROPN
fnp-3317	219	20	,	,	PUNCT
fnp-3317	219	21	wu	wu	PROPN
fnp-3317	219	22	,	,	PUNCT
fnp-3317	219	23	d.	d.	PROPN
fnp-3317	219	24	,	,	PUNCT
fnp-3317	219	25	thiruvalluvan	thiruvalluvan	PROPN
fnp-3317	219	26	,	,	PUNCT
fnp-3317	219	27	a.	a.	NOUN
fnp-3317	219	28	,	,	PUNCT
fnp-3317	219	29	cisternas	cisternas	NOUN
fnp-3317	219	30	-	-	PUNCT
fnp-3317	219	31	olmedo	olmedo	NOUN
fnp-3317	219	32	,	,	PUNCT
fnp-3317	219	33	m.	m.	NOUN
fnp-3317	219	34	,	,	PUNCT
fnp-3317	219	35	henríquez	henríquez	PROPN
fnp-3317	219	36	,	,	PUNCT
fnp-3317	219	37	d.	d.	PROPN
fnp-3317	219	38	r.	r.	PROPN
fnp-3317	219	39	,	,	PUNCT
fnp-3317	219	40	plate	plate	NOUN
fnp-3317	219	41	,	,	PUNCT
fnp-3317	219	42	l.	l.	PROPN
fnp-3317	219	43	,	,	PUNCT
fnp-3317	219	44	chana	chana	NOUN
fnp-3317	219	45	-	-	PUNCT
fnp-3317	219	46	cuevas	cuevas	PROPN
fnp-3317	219	47	,	,	PUNCT
fnp-3317	219	48	p.	p.	NOUN
fnp-3317	219	49	,	,	PUNCT
fnp-3317	219	50	saquel	saquel	PROPN
fnp-3317	219	51	,	,	PUNCT
fnp-3317	219	52	c.	c.	PROPN
fnp-3317	219	53	,	,	PUNCT
fnp-3317	219	54	thielen	thielen	VERB
fnp-3317	219	55	,	,	PUNCT
fnp-3317	219	56	p.	p.	NOUN
fnp-3317	219	57	,	,	PUNCT
fnp-3317	219	58	longo	longo	PROPN
fnp-3317	219	59	,	,	PUNCT
fnp-3317	219	60	k.	k.	PROPN
fnp-3317	219	61	a.	a.	PROPN
fnp-3317	219	62	,	,	PUNCT
fnp-3317	219	63	geddes	geddes	PROPN
fnp-3317	219	64	,	,	PUNCT
fnp-3317	219	65	b.	b.	PROPN
fnp-3317	219	66	j.	j.	PROPN
fnp-3317	219	67	,	,	PUNCT
fnp-3317	219	68	lederkremer	lederkremer	PROPN
fnp-3317	219	69	,	,	PUNCT
fnp-3317	219	70	g.	g.	PROPN
fnp-3317	219	71	z.	z.	PROPN
fnp-3317	219	72	,	,	PUNCT
fnp-3317	219	73	sharma	sharma	PROPN
fnp-3317	219	74	,	,	PUNCT
fnp-3317	219	75	n.	n.	NOUN
fnp-3317	219	76	,	,	PUNCT
fnp-3317	219	77	shenkman	shenkman	NOUN
fnp-3317	219	78	,	,	PUNCT
fnp-3317	219	79	m.	m.	NOUN
fnp-3317	219	80	,	,	PUNCT
fnp-3317	219	81	naphade	naphade	PROPN
fnp-3317	219	82	,	,	PUNCT
fnp-3317	219	83	s.	s.	PROPN
fnp-3317	219	84	,	,	PUNCT
fnp-3317	219	85	sardi	sardi	PROPN
fnp-3317	219	86	,	,	PUNCT
fnp-3317	219	87	s.	s.	PROPN
fnp-3317	219	88	p.	p.	PROPN
fnp-3317	219	89	,	,	PUNCT
fnp-3317	219	90	spichiger	spichiger	PROPN
fnp-3317	219	91	,	,	PUNCT
fnp-3317	219	92	c.	c.	PROPN
fnp-3317	219	93	,	,	PUNCT
fnp-3317	219	94	richter	richter	PROPN
fnp-3317	219	95	,	,	PUNCT
fnp-3317	219	96	h.	h.	PROPN
fnp-3317	219	97	g.	g.	PROPN
fnp-3317	219	98	,	,	PUNCT
fnp-3317	219	99	…	…	PUNCT
fnp-3317	219	100	hetz	hetz	VERB
fnp-3317	219	101	,	,	PUNCT
fnp-3317	219	102	c.	c.	PROPN
fnp-3317	219	103	(	(	PUNCT
fnp-3317	219	104	2020	2020	NUM
fnp-3317	219	105	)	)	PUNCT
fnp-3317	219	106	.	.	PUNCT
fnp-3317	220	1	insulin	insulin	NOUN
fnp-3317	220	2	-	-	PUNCT
fnp-3317	220	3	like	like	ADJ
fnp-3317	220	4	growth	growth	NOUN
fnp-3317	220	5	factor	factor	NOUN
fnp-3317	220	6	2	2	NUM
fnp-3317	220	7	(	(	PUNCT
fnp-3317	220	8	igf2	igf2	PROPN
fnp-3317	220	9	)	)	PUNCT
fnp-3317	220	10	protects	protect	VERB
fnp-3317	220	11	against	against	ADP
fnp-3317	220	12	huntington	huntington	PROPN
fnp-3317	220	13	’s	’s	PART
fnp-3317	220	14	disease	disease	NOUN
fnp-3317	220	15	through	through	ADP
fnp-3317	220	16	the	the	DET
fnp-3317	220	17	extracellular	extracellular	ADJ
fnp-3317	220	18	disposal	disposal	NOUN
fnp-3317	220	19	of	of	ADP
fnp-3317	220	20	protein	protein	NOUN
fnp-3317	220	21	aggregates	aggregate	NOUN
fnp-3317	220	22	.	.	PUNCT
fnp-3317	221	1	acta	acta	PROPN
fnp-3317	221	2	neuropathologica	neuropathologica	PROPN
fnp-3317	221	3	,	,	PUNCT
fnp-3317	221	4	140(5	140(5	NUM
fnp-3317	221	5	)	)	PUNCT
fnp-3317	221	6	,	,	PUNCT
fnp-3317	221	7	737–764	737–764	NUM
fnp-3317	221	8	.	.	PUNCT
fnp-3317	222	1	https://doi.org/10.1007/s00401-020-02183-1	https://doi.org/10.1007/s00401-020-02183-1	PROPN
fnp-3317	222	2	johnson	johnson	PROPN
fnp-3317	222	3	,	,	PUNCT
fnp-3317	222	4	e.	e.	PROPN
fnp-3317	222	5	c.	c.	PROPN
fnp-3317	222	6	b.	b.	PROPN
fnp-3317	222	7	,	,	PUNCT
fnp-3317	222	8	dammer	dammer	PROPN
fnp-3317	222	9	,	,	PUNCT
fnp-3317	222	10	e.	e.	PROPN
fnp-3317	222	11	b.	b.	PROPN
fnp-3317	222	12	,	,	PUNCT
fnp-3317	222	13	duong	duong	PROPN
fnp-3317	222	14	,	,	PUNCT
fnp-3317	222	15	d.	d.	PROPN
fnp-3317	222	16	m.	m.	PROPN
fnp-3317	222	17	,	,	PUNCT
fnp-3317	222	18	ping	ping	PROPN
fnp-3317	222	19	,	,	PUNCT
fnp-3317	222	20	l.	l.	PROPN
fnp-3317	222	21	,	,	PUNCT
fnp-3317	222	22	zhou	zhou	PROPN
fnp-3317	222	23	,	,	PUNCT
fnp-3317	222	24	m.	m.	NOUN
fnp-3317	222	25	,	,	PUNCT
fnp-3317	222	26	yin	yin	PROPN
fnp-3317	222	27	,	,	PUNCT
fnp-3317	222	28	l.	l.	PROPN
fnp-3317	222	29	,	,	PUNCT
fnp-3317	222	30	higginbotham	higginbotham	PROPN
fnp-3317	222	31	,	,	PUNCT
fnp-3317	222	32	l.	l.	PROPN
fnp-3317	222	33	a.	a.	PROPN
fnp-3317	222	34	,	,	PUNCT
fnp-3317	222	35	guajardo	guajardo	PROPN
fnp-3317	222	36	,	,	PUNCT
fnp-3317	222	37	a.	a.	NOUN
fnp-3317	222	38	,	,	PUNCT
fnp-3317	222	39	white	white	PROPN
fnp-3317	222	40	,	,	PUNCT
fnp-3317	222	41	b.	b.	PROPN
fnp-3317	222	42	,	,	PUNCT
fnp-3317	222	43	troncoso	troncoso	PROPN
fnp-3317	222	44	,	,	PUNCT
fnp-3317	222	45	j.	j.	PROPN
fnp-3317	222	46	c.	c.	PROPN
fnp-3317	222	47	,	,	PUNCT
fnp-3317	222	48	thambisetty	thambisetty	PROPN
fnp-3317	222	49	,	,	PUNCT
fnp-3317	222	50	m.	m.	NOUN
fnp-3317	222	51	,	,	PUNCT
fnp-3317	222	52	montine	montine	NOUN
fnp-3317	222	53	,	,	PUNCT
fnp-3317	222	54	t.	t.	PROPN
fnp-3317	222	55	j.	j.	PROPN
fnp-3317	222	56	,	,	PUNCT
fnp-3317	222	57	lee	lee	PROPN
fnp-3317	222	58	,	,	PUNCT
fnp-3317	222	59	e.	e.	PROPN
fnp-3317	222	60	b.	b.	PROPN
fnp-3317	222	61	,	,	PUNCT
fnp-3317	222	62	trojanowski	trojanowski	PROPN
fnp-3317	222	63	,	,	PUNCT
fnp-3317	222	64	j.	j.	PROPN
fnp-3317	222	65	q.	q.	PROPN
fnp-3317	222	66	,	,	PUNCT
fnp-3317	222	67	beach	beach	NOUN
fnp-3317	222	68	,	,	PUNCT
fnp-3317	222	69	t.	t.	PROPN
fnp-3317	222	70	g.	g.	PROPN
fnp-3317	222	71	,	,	PUNCT
fnp-3317	222	72	reiman	reiman	NOUN
fnp-3317	222	73	,	,	PUNCT
fnp-3317	222	74	e.	e.	PROPN
fnp-3317	222	75	m.	m.	PROPN
fnp-3317	222	76	,	,	PUNCT
fnp-3317	222	77	haroutunian	haroutunian	NOUN
fnp-3317	222	78	,	,	PUNCT
fnp-3317	222	79	v.	v.	PROPN
fnp-3317	222	80	,	,	PUNCT
fnp-3317	222	81	wang	wang	PROPN
fnp-3317	222	82	,	,	PUNCT
fnp-3317	222	83	m.	m.	NOUN
fnp-3317	222	84	,	,	PUNCT
fnp-3317	222	85	schadt	schadt	NOUN
fnp-3317	222	86	,	,	PUNCT
fnp-3317	222	87	e.	e.	PROPN
fnp-3317	222	88	,	,	PUNCT
fnp-3317	222	89	…	…	PUNCT
fnp-3317	222	90	seyfried	seyfried	ADJ
fnp-3317	222	91	,	,	PUNCT
fnp-3317	222	92	n.	n.	NOUN
fnp-3317	222	93	t.	t.	PROPN
fnp-3317	222	94	(	(	PUNCT
fnp-3317	222	95	2020	2020	NUM
fnp-3317	222	96	)	)	PUNCT
fnp-3317	222	97	.	.	PUNCT
fnp-3317	223	1	large	large	ADJ
fnp-3317	223	2	-	-	PUNCT
fnp-3317	223	3	scale	scale	NOUN
fnp-3317	223	4	proteomic	proteomic	ADJ
fnp-3317	223	5	analysis	analysis	NOUN
fnp-3317	223	6	of	of	ADP
fnp-3317	223	7	alzheimer	alzheimer	PROPN
fnp-3317	223	8	’s	’s	PART
fnp-3317	223	9	disease	disease	NOUN
fnp-3317	223	10	brain	brain	NOUN
fnp-3317	223	11	and	and	CCONJ
fnp-3317	223	12	cerebrospinal	cerebrospinal	ADJ
fnp-3317	223	13	fluid	fluid	NOUN
fnp-3317	223	14	reveals	reveal	VERB
fnp-3317	223	15	early	early	ADJ
fnp-3317	223	16	changes	change	NOUN
fnp-3317	223	17	in	in	ADP
fnp-3317	223	18	energy	energy	NOUN
fnp-3317	223	19	metabolism	metabolism	NOUN
fnp-3317	223	20	associated	associate	VERB
fnp-3317	223	21	with	with	ADP
fnp-3317	223	22	microglia	microglia	ADJ
fnp-3317	223	23	and	and	CCONJ
fnp-3317	223	24	astrocyte	astrocyte	NOUN
fnp-3317	223	25	activation	activation	NOUN
fnp-3317	223	26	.	.	PUNCT
fnp-3317	224	1	nature	nature	NOUN
fnp-3317	224	2	medicine	medicine	NOUN
fnp-3317	224	3	,	,	PUNCT
fnp-3317	224	4	26(5	26(5	NUM
fnp-3317	224	5	)	)	PUNCT
fnp-3317	224	6	,	,	PUNCT
fnp-3317	224	7	769–780	769–780	NUM
fnp-3317	224	8	.	.	NOUN
fnp-3317	224	9	https://doi.org/10.1038/s41591-020-0815-6	https://doi.org/10.1038/s41591-020-0815-6	PROPN
fnp-3317	224	10	kovacs	kovacs	PROPN
fnp-3317	224	11	,	,	PUNCT
fnp-3317	224	12	g.	g.	PROPN
fnp-3317	224	13	g.	g.	PROPN
fnp-3317	224	14	,	,	PUNCT
fnp-3317	224	15	ferrer	ferrer	PROPN
fnp-3317	224	16	,	,	PUNCT
fnp-3317	224	17	i.	i.	PROPN
fnp-3317	224	18	,	,	PUNCT
fnp-3317	224	19	grinberg	grinberg	PROPN
fnp-3317	224	20	,	,	PUNCT
fnp-3317	224	21	l.	l.	PROPN
fnp-3317	224	22	t.	t.	PROPN
fnp-3317	224	23	,	,	PUNCT
fnp-3317	224	24	alafuzoff	alafuzoff	NOUN
fnp-3317	224	25	,	,	PUNCT
fnp-3317	224	26	i.	i.	NOUN
fnp-3317	224	27	,	,	PUNCT
fnp-3317	224	28	attems	attems	PROPN
fnp-3317	224	29	,	,	PUNCT
fnp-3317	224	30	j.	j.	PROPN
fnp-3317	224	31	,	,	PUNCT
fnp-3317	224	32	budka	budka	PROPN
fnp-3317	224	33	,	,	PUNCT
fnp-3317	224	34	h.	h.	PROPN
fnp-3317	224	35	,	,	PUNCT
fnp-3317	224	36	cairns	cairns	PROPN
fnp-3317	224	37	,	,	PUNCT
fnp-3317	224	38	n.	n.	PROPN
fnp-3317	224	39	j.	j.	PROPN
fnp-3317	224	40	,	,	PUNCT
fnp-3317	224	41	crary	crary	PROPN
fnp-3317	224	42	,	,	PUNCT
fnp-3317	224	43	j.	j.	PROPN
fnp-3317	224	44	f.	f.	PROPN
fnp-3317	224	45	,	,	PUNCT
fnp-3317	224	46	duyckaerts	duyckaert	NOUN
fnp-3317	224	47	,	,	PUNCT
fnp-3317	224	48	c.	c.	NOUN
fnp-3317	224	49	,	,	PUNCT
fnp-3317	224	50	ghetti	ghetti	PROPN
fnp-3317	224	51	,	,	PUNCT
fnp-3317	224	52	b.	b.	PROPN
fnp-3317	224	53	,	,	PUNCT
fnp-3317	224	54	halliday	halliday	PROPN
fnp-3317	224	55	,	,	PUNCT
fnp-3317	224	56	g.	g.	PROPN
fnp-3317	224	57	m.	m.	PROPN
fnp-3317	224	58	,	,	PUNCT
fnp-3317	224	59	ironside	ironside	PROPN
fnp-3317	224	60	,	,	PUNCT
fnp-3317	224	61	j.	j.	PROPN
fnp-3317	224	62	w.	w.	PROPN
fnp-3317	224	63	,	,	PUNCT
fnp-3317	224	64	love	love	PROPN
fnp-3317	224	65	,	,	PUNCT
fnp-3317	224	66	s.	s.	PROPN
fnp-3317	224	67	,	,	PUNCT
fnp-3317	224	68	mackenzie	mackenzie	PROPN
fnp-3317	224	69	,	,	PUNCT
fnp-3317	224	70	i.	i.	PROPN
fnp-3317	224	71	r.	r.	PROPN
fnp-3317	224	72	,	,	PUNCT
fnp-3317	224	73	munoz	munoz	PROPN
fnp-3317	224	74	,	,	PUNCT
fnp-3317	224	75	d.	d.	PROPN
fnp-3317	224	76	g.	g.	PROPN
fnp-3317	224	77	,	,	PUNCT
fnp-3317	224	78	murray	murray	PROPN
fnp-3317	224	79	,	,	PUNCT
fnp-3317	224	80	m.	m.	PROPN
fnp-3317	224	81	e.	e.	PROPN
fnp-3317	224	82	,	,	PUNCT
fnp-3317	224	83	nelson	nelson	PROPN
fnp-3317	224	84	,	,	PUNCT
fnp-3317	224	85	p.	p.	PROPN
fnp-3317	224	86	t.	t.	PROPN
fnp-3317	224	87	,	,	PUNCT
fnp-3317	224	88	takahashi	takahashi	PROPN
fnp-3317	224	89	,	,	PUNCT
fnp-3317	224	90	h.	h.	PROPN
fnp-3317	224	91	,	,	PUNCT
fnp-3317	224	92	trojanowski	trojanowski	PROPN
fnp-3317	224	93	,	,	PUNCT
fnp-3317	224	94	j.	j.	PROPN
fnp-3317	224	95	q.	q.	PROPN
fnp-3317	224	96	,	,	PUNCT
fnp-3317	224	97	…	…	PUNCT
fnp-3317	224	98	dickson	dickson	PROPN
fnp-3317	224	99	,	,	PUNCT
fnp-3317	224	100	d.	d.	PROPN
fnp-3317	224	101	w.	w.	PROPN
fnp-3317	224	102	(	(	PUNCT
fnp-3317	224	103	2016	2016	NUM
fnp-3317	224	104	)	)	PUNCT
fnp-3317	224	105	.	.	PUNCT
fnp-3317	225	1	aging	age	VERB
fnp-3317	225	2	-	-	PUNCT
fnp-3317	225	3	related	relate	VERB
fnp-3317	225	4	tau	tau	PROPN
fnp-3317	225	5	astrogliopathy	astrogliopathy	ADJ
fnp-3317	225	6	(	(	PUNCT
fnp-3317	225	7	artag	artag	ADJ
fnp-3317	225	8	):	):	PUNCT
fnp-3317	225	9	harmonized	harmonized	ADJ
fnp-3317	225	10	evaluation	evaluation	NOUN
fnp-3317	225	11	strategy	strategy	NOUN
fnp-3317	225	12	.	.	PUNCT
fnp-3317	226	1	acta	acta	PROPN
fnp-3317	226	2	neuropathologica	neuropathologica	PROPN
fnp-3317	226	3	,	,	PUNCT
fnp-3317	226	4	131(1	131(1	NUM
fnp-3317	226	5	)	)	PUNCT
fnp-3317	226	6	,	,	PUNCT
fnp-3317	226	7	87–102	87–102	PROPN
fnp-3317	226	8	.	.	PUNCT
fnp-3317	227	1	https://doi.org/10.1007/s00401-015-1509-x	https://doi.org/10.1007/s00401-015-1509-x	PROPN
fnp-3317	227	2	lau	lau	PROPN
fnp-3317	227	3	,	,	PUNCT
fnp-3317	227	4	a.	a.	PROPN
fnp-3317	227	5	,	,	PUNCT
fnp-3317	227	6	so	so	ADV
fnp-3317	227	7	,	,	PUNCT
fnp-3317	227	8	r.	r.	PROPN
fnp-3317	227	9	w.	w.	PROPN
fnp-3317	227	10	l.	l.	PROPN
fnp-3317	227	11	,	,	PUNCT
fnp-3317	227	12	lau	lau	PROPN
fnp-3317	227	13	,	,	PUNCT
fnp-3317	227	14	h.	h.	PROPN
fnp-3317	227	15	h.	h.	PROPN
fnp-3317	227	16	c.	c.	PROPN
fnp-3317	227	17	,	,	PUNCT
fnp-3317	227	18	sang	sing	VERB
fnp-3317	227	19	,	,	PUNCT
fnp-3317	227	20	j.	j.	PROPN
fnp-3317	227	21	c.	c.	PROPN
fnp-3317	227	22	,	,	PUNCT
fnp-3317	227	23	ruiz	ruiz	NOUN
fnp-3317	227	24	-	-	PUNCT
fnp-3317	227	25	riquelme	riquelme	NOUN
fnp-3317	227	26	,	,	PUNCT
fnp-3317	227	27	a.	a.	NOUN
fnp-3317	227	28	,	,	PUNCT
fnp-3317	227	29	fleck	fleck	NOUN
fnp-3317	227	30	,	,	PUNCT
fnp-3317	227	31	s.	s.	PROPN
fnp-3317	227	32	c.	c.	PROPN
fnp-3317	227	33	,	,	PUNCT
fnp-3317	227	34	stuart	stuart	PROPN
fnp-3317	227	35	,	,	PUNCT
fnp-3317	227	36	e.	e.	PROPN
fnp-3317	227	37	,	,	PUNCT
fnp-3317	227	38	menon	menon	PROPN
fnp-3317	227	39	,	,	PUNCT
fnp-3317	227	40	s.	s.	PROPN
fnp-3317	227	41	,	,	PUNCT
fnp-3317	227	42	visanji	visanji	PROPN
fnp-3317	227	43	,	,	PUNCT
fnp-3317	227	44	n.	n.	PROPN
fnp-3317	227	45	p.	p.	PROPN
fnp-3317	227	46	,	,	PUNCT
fnp-3317	227	47	meisl	meisl	PROPN
fnp-3317	227	48	,	,	PUNCT
fnp-3317	227	49	g.	g.	PROPN
fnp-3317	227	50	,	,	PUNCT
fnp-3317	227	51	faidi	faidi	PROPN
fnp-3317	227	52	,	,	PUNCT
fnp-3317	227	53	r.	r.	PROPN
fnp-3317	227	54	,	,	PUNCT
fnp-3317	227	55	marano	marano	PROPN
fnp-3317	227	56	,	,	PUNCT
fnp-3317	227	57	m.	m.	NOUN
fnp-3317	227	58	m.	m.	NOUN
fnp-3317	227	59	,	,	PUNCT
fnp-3317	227	60	schmitt	schmitt	NOUN
fnp-3317	227	61	-	-	PUNCT
fnp-3317	227	62	ulms	ulm	NOUN
fnp-3317	227	63	,	,	PUNCT
fnp-3317	227	64	c.	c.	PROPN
fnp-3317	227	65	,	,	PUNCT
fnp-3317	227	66	wang	wang	PROPN
fnp-3317	227	67	,	,	PUNCT
fnp-3317	227	68	z.	z.	PROPN
fnp-3317	227	69	,	,	PUNCT
fnp-3317	227	70	fraser	fraser	PROPN
fnp-3317	227	71	,	,	PUNCT
fnp-3317	227	72	p.	p.	PROPN
fnp-3317	227	73	e.	e.	PROPN
fnp-3317	227	74	,	,	PUNCT
fnp-3317	227	75	tandon	tandon	PROPN
fnp-3317	227	76	,	,	PUNCT
fnp-3317	227	77	a.	a.	PROPN
fnp-3317	227	78	,	,	PUNCT
fnp-3317	227	79	hyman	hyman	PROPN
fnp-3317	227	80	,	,	PUNCT
fnp-3317	227	81	b.	b.	PROPN
fnp-3317	227	82	t.	t.	PROPN
fnp-3317	227	83	,	,	PUNCT
fnp-3317	227	84	wille	wille	NOUN
fnp-3317	227	85	,	,	PUNCT
fnp-3317	227	86	h.	h.	PROPN
fnp-3317	227	87	,	,	PUNCT
fnp-3317	227	88	ingelsson	ingelsson	PROPN
fnp-3317	227	89	,	,	PUNCT
fnp-3317	227	90	m.	m.	NOUN
fnp-3317	227	91	,	,	PUNCT
fnp-3317	227	92	…	…	PUNCT
fnp-3317	227	93	watts	watts	PROPN
fnp-3317	227	94	,	,	PUNCT
fnp-3317	227	95	j.	j.	PROPN
fnp-3317	227	96	c.	c.	PROPN
fnp-3317	227	97	(	(	PUNCT
fnp-3317	227	98	2020	2020	NUM
fnp-3317	227	99	)	)	PUNCT
fnp-3317	227	100	.	.	PUNCT
fnp-3317	228	1	α	α	X
fnp-3317	228	2	-	-	PUNCT
fnp-3317	228	3	synuclein	synuclein	NOUN
fnp-3317	228	4	strains	strain	NOUN
fnp-3317	228	5	target	target	VERB
fnp-3317	228	6	distinct	distinct	ADJ
fnp-3317	228	7	brain	brain	NOUN
fnp-3317	228	8	regions	region	NOUN
fnp-3317	228	9	and	and	CCONJ
fnp-3317	228	10	cell	cell	NOUN
fnp-3317	228	11	types	type	NOUN
fnp-3317	228	12	.	.	PUNCT
fnp-3317	229	1	nature	nature	NOUN
fnp-3317	229	2	neuroscience	neuroscience	NOUN
fnp-3317	229	3	,	,	PUNCT
fnp-3317	229	4	23(1	23(1	NUM
fnp-3317	229	5	)	)	PUNCT
fnp-3317	229	6	,	,	PUNCT
fnp-3317	229	7	21–31	21–31	NUM
fnp-3317	229	8	.	.	PUNCT
fnp-3317	230	1	https://doi.org/10.1038/s41593-019-0541-x	https://doi.org/10.1038/s41593-019-0541-x	PROPN
fnp-3317	230	2	mair	mair	PROPN
fnp-3317	230	3	,	,	PUNCT
fnp-3317	230	4	w.	w.	PROPN
fnp-3317	230	5	,	,	PUNCT
fnp-3317	230	6	muntel	muntel	PROPN
fnp-3317	230	7	,	,	PUNCT
fnp-3317	230	8	j.	j.	PROPN
fnp-3317	230	9	,	,	PUNCT
fnp-3317	230	10	tepper	tepper	PROPN
fnp-3317	230	11	,	,	PUNCT
fnp-3317	230	12	k.	k.	PROPN
fnp-3317	230	13	,	,	PUNCT
fnp-3317	230	14	tang	tang	PROPN
fnp-3317	230	15	,	,	PUNCT
fnp-3317	230	16	s.	s.	PROPN
fnp-3317	230	17	,	,	PUNCT
fnp-3317	230	18	biernat	biernat	PROPN
fnp-3317	230	19	,	,	PUNCT
fnp-3317	230	20	j.	j.	PROPN
fnp-3317	230	21	,	,	PUNCT
fnp-3317	230	22	seeley	seeley	PROPN
fnp-3317	230	23	,	,	PUNCT
fnp-3317	230	24	w.	w.	PROPN
fnp-3317	230	25	w.	w.	PROPN
fnp-3317	230	26	,	,	PUNCT
fnp-3317	230	27	kosik	kosik	PROPN
fnp-3317	230	28	,	,	PUNCT
fnp-3317	230	29	k.	k.	PROPN
fnp-3317	230	30	s.	s.	PROPN
fnp-3317	230	31	,	,	PUNCT
fnp-3317	230	32	mandelkow	mandelkow	PROPN
fnp-3317	230	33	,	,	PUNCT
fnp-3317	230	34	e.	e.	PROPN
fnp-3317	230	35	,	,	PUNCT
fnp-3317	230	36	steen	steen	PROPN
fnp-3317	230	37	,	,	PUNCT
fnp-3317	230	38	h.	h.	PROPN
fnp-3317	230	39	,	,	PUNCT
fnp-3317	230	40	&	&	CCONJ
fnp-3317	230	41	steen	steen	PROPN
fnp-3317	230	42	,	,	PUNCT
fnp-3317	230	43	j.	j.	PROPN
fnp-3317	230	44	a.	a.	PROPN
fnp-3317	230	45	(	(	PUNCT
fnp-3317	230	46	2016	2016	NUM
fnp-3317	230	47	)	)	PUNCT
fnp-3317	230	48	.	.	PUNCT
fnp-3317	231	1	flexitau	flexitau	ADV
fnp-3317	231	2	:	:	PUNCT
fnp-3317	231	3	quantifying	quantify	VERB
fnp-3317	231	4	post	post	ADJ
fnp-3317	231	5	-	-	ADJ
fnp-3317	231	6	translational	translational	ADJ
fnp-3317	231	7	modifications	modification	NOUN
fnp-3317	231	8	of	of	ADP
fnp-3317	231	9	tau	tau	PROPN
fnp-3317	231	10	protein	protein	NOUN
fnp-3317	231	11	in	in	ADP
fnp-3317	231	12	vitro	vitro	X
fnp-3317	231	13	and	and	CCONJ
fnp-3317	231	14	in	in	ADP
fnp-3317	231	15	human	human	ADJ
fnp-3317	231	16	disease	disease	NOUN
fnp-3317	231	17	.	.	PUNCT
fnp-3317	232	1	analytical	analytical	ADJ
fnp-3317	232	2	chemistry	chemistry	NOUN
fnp-3317	232	3	,	,	PUNCT
fnp-3317	232	4	88(7	88(7	NUM
fnp-3317	232	5	)	)	PUNCT
fnp-3317	232	6	,	,	PUNCT
fnp-3317	232	7	3704–3714	3704–3714	NUM
fnp-3317	232	8	.	.	PUNCT
fnp-3317	233	1	https://doi.org/10.1021/acs.analchem.5b04509	https://doi.org/10.1021/acs.analchem.5b04509	PROPN
fnp-3317	233	2	mckee	mckee	PROPN
fnp-3317	233	3	,	,	PUNCT
fnp-3317	233	4	a.	a.	PROPN
fnp-3317	233	5	c.	c.	PROPN
fnp-3317	233	6	,	,	PUNCT
fnp-3317	233	7	cairns	cairns	PROPN
fnp-3317	233	8	,	,	PUNCT
fnp-3317	233	9	n.	n.	PROPN
fnp-3317	233	10	j.	j.	PROPN
fnp-3317	233	11	,	,	PUNCT
fnp-3317	233	12	dickson	dickson	PROPN
fnp-3317	233	13	,	,	PUNCT
fnp-3317	233	14	d.	d.	PROPN
fnp-3317	233	15	w.	w.	PROPN
fnp-3317	233	16	,	,	PUNCT
fnp-3317	233	17	folkerth	folkerth	PROPN
fnp-3317	233	18	,	,	PUNCT
fnp-3317	233	19	r.	r.	PROPN
fnp-3317	233	20	d.	d.	PROPN
fnp-3317	233	21	,	,	PUNCT
fnp-3317	233	22	keene	keene	PROPN
fnp-3317	233	23	,	,	PUNCT
fnp-3317	233	24	c.	c.	PROPN
fnp-3317	233	25	d.	d.	PROPN
fnp-3317	233	26	,	,	PUNCT
fnp-3317	233	27	litvan	litvan	PROPN
fnp-3317	233	28	,	,	PUNCT
fnp-3317	233	29	i.	i.	PROPN
fnp-3317	233	30	,	,	PUNCT
fnp-3317	233	31	perl	perl	PROPN
fnp-3317	233	32	,	,	PUNCT
fnp-3317	233	33	d.	d.	PROPN
fnp-3317	233	34	p.	p.	PROPN
fnp-3317	233	35	,	,	PUNCT
fnp-3317	233	36	stein	stein	PROPN
fnp-3317	233	37	,	,	PUNCT
fnp-3317	233	38	t.	t.	PROPN
fnp-3317	233	39	d.	d.	PROPN
fnp-3317	233	40	,	,	PUNCT
fnp-3317	233	41	vonsattel	vonsattel	NOUN
fnp-3317	233	42	,	,	PUNCT
fnp-3317	233	43	j.-p	j.-p	PROPN
fnp-3317	233	44	.	.	PROPN
fnp-3317	233	45	,	,	PUNCT
fnp-3317	233	46	stewart	stewart	PROPN
fnp-3317	233	47	,	,	PUNCT
fnp-3317	233	48	w.	w.	PROPN
fnp-3317	233	49	,	,	PUNCT
fnp-3317	233	50	tripodis	tripodi	NOUN
fnp-3317	233	51	,	,	PUNCT
fnp-3317	233	52	y.	y.	PROPN
fnp-3317	233	53	,	,	PUNCT
fnp-3317	233	54	crary	crary	NOUN
fnp-3317	233	55	,	,	PUNCT
fnp-3317	233	56	j.	j.	PROPN
fnp-3317	233	57	f.	f.	PROPN
fnp-3317	233	58	,	,	PUNCT
fnp-3317	233	59	bieniek	bieniek	PROPN
fnp-3317	233	60	,	,	PUNCT
fnp-3317	233	61	k.	k.	PROPN
fnp-3317	233	62	f.	f.	PROPN
fnp-3317	233	63	,	,	PUNCT
fnp-3317	233	64	dams	dams	NOUN
fnp-3317	233	65	-	-	PUNCT
fnp-3317	233	66	o’connor	o’connor	ADV
fnp-3317	233	67	,	,	PUNCT
fnp-3317	233	68	k.	k.	PROPN
fnp-3317	233	69	,	,	PUNCT
fnp-3317	233	70	alvarez	alvarez	PROPN
fnp-3317	233	71	,	,	PUNCT
fnp-3317	233	72	v.	v.	PROPN
fnp-3317	233	73	e.	e.	PROPN
fnp-3317	233	74	,	,	PUNCT
fnp-3317	233	75	gordon	gordon	PROPN
fnp-3317	233	76	,	,	PUNCT
fnp-3317	233	77	w.	w.	PROPN
fnp-3317	233	78	a.	a.	PROPN
fnp-3317	233	79	,	,	PUNCT
fnp-3317	233	80	&	&	CCONJ
fnp-3317	233	81	tbi	tbi	PROPN
fnp-3317	233	82	/	/	SYM
fnp-3317	233	83	cte	cte	PROPN
fnp-3317	233	84	group	group	NOUN
fnp-3317	233	85	.	.	PUNCT
fnp-3317	234	1	(	(	PUNCT
fnp-3317	234	2	2016	2016	NUM
fnp-3317	234	3	)	)	PUNCT
fnp-3317	234	4	.	.	PUNCT
fnp-3317	235	1	the	the	DET
fnp-3317	235	2	first	first	ADJ
fnp-3317	235	3	ninds	nind	NOUN
fnp-3317	235	4	/	/	SYM
fnp-3317	235	5	nibib	nibib	NOUN
fnp-3317	235	6	consensus	consensus	NOUN
fnp-3317	235	7	meeting	meeting	NOUN
fnp-3317	235	8	to	to	PART
fnp-3317	235	9	define	define	VERB
fnp-3317	235	10	neuropathological	neuropathological	ADJ
fnp-3317	235	11	criteria	criterion	NOUN
fnp-3317	235	12	for	for	ADP
fnp-3317	235	13	the	the	DET
fnp-3317	235	14	diagnosis	diagnosis	NOUN
fnp-3317	235	15	of	of	ADP
fnp-3317	235	16	chronic	chronic	ADJ
fnp-3317	235	17	traumatic	traumatic	ADJ
fnp-3317	235	18	encephalopathy	encephalopathy	NOUN
fnp-3317	235	19	.	.	PUNCT
fnp-3317	236	1	acta	acta	PROPN
fnp-3317	236	2	neuropathologica	neuropathologica	PROPN
fnp-3317	236	3	,	,	PUNCT
fnp-3317	236	4	131(1	131(1	NUM
fnp-3317	236	5	)	)	PUNCT
fnp-3317	236	6	,	,	PUNCT
fnp-3317	236	7	75–86	75–86	NUM
fnp-3317	236	8	.	.	PUNCT
fnp-3317	237	1	https://doi.org/10.1007/s00401-015-1515-z	https://doi.org/10.1007/s00401-015-1515-z	INTJ
fnp-3317	237	2	mckee	mckee	PROPN
fnp-3317	237	3	,	,	PUNCT
fnp-3317	237	4	a.	a.	PROPN
fnp-3317	237	5	c.	c.	PROPN
fnp-3317	237	6	,	,	PUNCT
fnp-3317	237	7	stein	stein	PROPN
fnp-3317	237	8	,	,	PUNCT
fnp-3317	237	9	t.	t.	PROPN
fnp-3317	237	10	d.	d.	PROPN
fnp-3317	237	11	,	,	PUNCT
fnp-3317	237	12	crary	crary	PROPN
fnp-3317	237	13	,	,	PUNCT
fnp-3317	237	14	j.	j.	PROPN
fnp-3317	237	15	f.	f.	PROPN
fnp-3317	237	16	,	,	PUNCT
fnp-3317	237	17	bieniek	bieniek	PROPN
fnp-3317	237	18	,	,	PUNCT
fnp-3317	237	19	k.	k.	PROPN
fnp-3317	237	20	f.	f.	PROPN
fnp-3317	237	21	,	,	PUNCT
fnp-3317	237	22	cantu	cantu	PROPN
fnp-3317	237	23	,	,	PUNCT
fnp-3317	237	24	r.	r.	PROPN
fnp-3317	237	25	c.	c.	PROPN
fnp-3317	237	26	,	,	PUNCT
fnp-3317	237	27	&	&	CCONJ
fnp-3317	237	28	kovacs	kovacs	PROPN
fnp-3317	237	29	,	,	PUNCT
fnp-3317	237	30	g.	g.	PROPN
fnp-3317	237	31	g.	g.	PROPN
fnp-3317	237	32	(	(	PUNCT
fnp-3317	237	33	2020	2020	NUM
fnp-3317	237	34	)	)	PUNCT
fnp-3317	237	35	.	.	PUNCT
fnp-3317	238	1	practical	practical	ADJ
fnp-3317	238	2	considerations	consideration	NOUN
fnp-3317	238	3	in	in	ADP
fnp-3317	238	4	the	the	DET
fnp-3317	238	5	diagnosis	diagnosis	NOUN
fnp-3317	238	6	of	of	ADP
fnp-3317	238	7	mild	mild	ADJ
fnp-3317	238	8	chronic	chronic	ADJ
fnp-3317	238	9	traumatic	traumatic	ADJ
fnp-3317	238	10	encephalopathy	encephalopathy	NOUN
fnp-3317	238	11	and	and	CCONJ
fnp-3317	238	12	distinction	distinction	NOUN
fnp-3317	238	13	from	from	ADP
fnp-3317	238	14	age	age	NOUN
fnp-3317	238	15	-	-	PUNCT
fnp-3317	238	16	related	relate	VERB
fnp-3317	238	17	tau	tau	PROPN
fnp-3317	238	18	astrogliopathy	astrogliopathy	PROPN
fnp-3317	238	19	.	.	PUNCT
fnp-3317	239	1	journal	journal	PROPN
fnp-3317	239	2	of	of	ADP
fnp-3317	239	3	neuropathology	neuropathology	NOUN
fnp-3317	239	4	and	and	CCONJ
fnp-3317	239	5	experimental	experimental	ADJ
fnp-3317	239	6	neurology	neurology	NOUN
fnp-3317	239	7	,	,	PUNCT
fnp-3317	239	8	79(8	79(8	NUM
fnp-3317	239	9	)	)	PUNCT
fnp-3317	239	10	,	,	PUNCT
fnp-3317	239	11	921–924	921–924	NUM
fnp-3317	239	12	.	.	PUNCT
fnp-3317	240	1	https://doi.org/10.1093/jnen/nlaa047	https://doi.org/10.1093/jnen/nlaa047	PROPN
fnp-3317	240	2	morgello	morgello	PROPN
fnp-3317	240	3	,	,	PUNCT
fnp-3317	240	4	s.	s.	PROPN
fnp-3317	240	5	(	(	PUNCT
fnp-3317	240	6	2020	2020	NUM
fnp-3317	240	7	,	,	PUNCT
fnp-3317	240	8	august	august	PROPN
fnp-3317	240	9	)	)	PUNCT
fnp-3317	240	10	.	.	PUNCT
fnp-3317	241	1	coronaviruses	coronaviruse	NOUN
fnp-3317	241	2	and	and	CCONJ
fnp-3317	241	3	the	the	DET
fnp-3317	241	4	central	central	ADJ
fnp-3317	241	5	nervous	nervous	ADJ
fnp-3317	241	6	system	system	NOUN
fnp-3317	241	7	.	.	PUNCT
fnp-3317	242	1	journal	journal	NOUN
fnp-3317	242	2	of	of	ADP
fnp-3317	242	3	neurovirology	neurovirology	NOUN
fnp-3317	242	4	;	;	PUNCT
fnp-3317	242	5	j	j	PROPN
fnp-3317	242	6	neurovirol	neurovirol	NOUN
fnp-3317	242	7	.	.	PUNCT
fnp-3317	243	1	https://doi.org/10.1007/s13365-020-00868-7	https://doi.org/10.1007/s13365-020-00868-7	PROPN
fnp-3317	243	2	reichard	reichard	PROPN
fnp-3317	243	3	,	,	PUNCT
fnp-3317	243	4	r.	r.	PROPN
fnp-3317	243	5	r.	r.	PROPN
fnp-3317	243	6	,	,	PUNCT
fnp-3317	243	7	kashani	kashani	PROPN
fnp-3317	243	8	,	,	PUNCT
fnp-3317	243	9	k.	k.	PROPN
fnp-3317	243	10	b.	b.	PROPN
fnp-3317	243	11	,	,	PUNCT
fnp-3317	243	12	boire	boire	PROPN
fnp-3317	243	13	,	,	PUNCT
fnp-3317	243	14	n.	n.	NOUN
fnp-3317	243	15	a.	a.	PROPN
fnp-3317	243	16	,	,	PUNCT
fnp-3317	243	17	constantopoulos	constantopoulo	NOUN
fnp-3317	243	18	,	,	PUNCT
fnp-3317	243	19	e.	e.	PROPN
fnp-3317	243	20	,	,	PUNCT
fnp-3317	243	21	guo	guo	PROPN
fnp-3317	243	22	,	,	PUNCT
fnp-3317	243	23	y.	y.	PROPN
fnp-3317	243	24	,	,	PUNCT
fnp-3317	243	25	&	&	CCONJ
fnp-3317	243	26	lucchinetti	lucchinetti	PROPN
fnp-3317	243	27	,	,	PUNCT
fnp-3317	243	28	c.	c.	PROPN
fnp-3317	243	29	f.	f.	PROPN
fnp-3317	243	30	(	(	PUNCT
fnp-3317	243	31	2020	2020	NUM
fnp-3317	243	32	)	)	PUNCT
fnp-3317	243	33	.	.	PUNCT
fnp-3317	244	1	neuropathology	neuropathology	NOUN
fnp-3317	244	2	of	of	ADP
fnp-3317	244	3	covid-19	covid-19	PROPN
fnp-3317	244	4	:	:	PUNCT
fnp-3317	244	5	a	a	DET
fnp-3317	244	6	spectrum	spectrum	NOUN
fnp-3317	244	7	of	of	ADP
fnp-3317	244	8	vascular	vascular	NOUN
fnp-3317	244	9	and	and	CCONJ
fnp-3317	244	10	acute	acute	ADJ
fnp-3317	244	11	disseminated	disseminate	VERB
fnp-3317	244	12	encephalomyelitis	encephalomyelitis	NOUN
fnp-3317	244	13	(	(	PUNCT
fnp-3317	244	14	adem)-like	adem)-like	ADP
fnp-3317	244	15	pathology	pathology	NOUN
fnp-3317	244	16	.	.	PUNCT
fnp-3317	245	1	acta	acta	PROPN
fnp-3317	245	2	neuropathologica	neuropathologica	PROPN
fnp-3317	245	3	,	,	PUNCT
fnp-3317	245	4	140(1	140(1	NUM
fnp-3317	245	5	)	)	PUNCT
fnp-3317	245	6	,	,	PUNCT
fnp-3317	245	7	1–6	1–6	NUM
fnp-3317	245	8	.	.	PUNCT
fnp-3317	245	9	https://doi.org/10.1007/s00401-020-02166-2	https://doi.org/10.1007/s00401-020-02166-2	NOUN
fnp-3317	245	10	schweighauser	schweighauser	NOUN
fnp-3317	245	11	,	,	PUNCT
fnp-3317	245	12	m.	m.	NOUN
fnp-3317	245	13	,	,	PUNCT
fnp-3317	245	14	shi	shi	PROPN
fnp-3317	245	15	,	,	PUNCT
fnp-3317	245	16	y.	y.	PROPN
fnp-3317	245	17	,	,	PUNCT
fnp-3317	245	18	tarutani	tarutani	PROPN
fnp-3317	245	19	,	,	PUNCT
fnp-3317	245	20	a.	a.	NOUN
fnp-3317	245	21	,	,	PUNCT
fnp-3317	245	22	kametani	kametani	PROPN
fnp-3317	245	23	,	,	PUNCT
fnp-3317	245	24	f.	f.	PROPN
fnp-3317	245	25	,	,	PUNCT
fnp-3317	245	26	murzin	murzin	PROPN
fnp-3317	245	27	,	,	PUNCT
fnp-3317	245	28	a.	a.	NOUN
fnp-3317	245	29	g.	g.	PROPN
fnp-3317	245	30	,	,	PUNCT
fnp-3317	245	31	ghetti	ghetti	PROPN
fnp-3317	245	32	,	,	PUNCT
fnp-3317	245	33	b.	b.	PROPN
fnp-3317	245	34	,	,	PUNCT
fnp-3317	245	35	matsubara	matsubara	PROPN
fnp-3317	245	36	,	,	PUNCT
fnp-3317	245	37	t.	t.	PROPN
fnp-3317	245	38	,	,	PUNCT
fnp-3317	245	39	tomita	tomita	PROPN
fnp-3317	245	40	,	,	PUNCT
fnp-3317	245	41	t.	t.	PROPN
fnp-3317	245	42	,	,	PUNCT
fnp-3317	245	43	ando	ando	PROPN
fnp-3317	245	44	,	,	PUNCT
fnp-3317	245	45	t.	t.	PROPN
fnp-3317	245	46	,	,	PUNCT
fnp-3317	245	47	hasegawa	hasegawa	PROPN
fnp-3317	245	48	,	,	PUNCT
fnp-3317	245	49	k.	k.	PROPN
fnp-3317	245	50	,	,	PUNCT
fnp-3317	245	51	murayama	murayama	PROPN
fnp-3317	245	52	,	,	PUNCT
fnp-3317	245	53	s.	s.	PROPN
fnp-3317	245	54	,	,	PUNCT
fnp-3317	245	55	yoshida	yoshida	PROPN
fnp-3317	245	56	,	,	PUNCT
fnp-3317	245	57	m.	m.	NOUN
fnp-3317	245	58	,	,	PUNCT
fnp-3317	245	59	hasegawa	hasegawa	PROPN
fnp-3317	245	60	,	,	PUNCT
fnp-3317	245	61	m.	m.	NOUN
fnp-3317	245	62	,	,	PUNCT
fnp-3317	245	63	scheres	schere	NOUN
fnp-3317	245	64	,	,	PUNCT
fnp-3317	245	65	s.	s.	PROPN
fnp-3317	245	66	h.	h.	PROPN
fnp-3317	245	67	w.	w.	PROPN
fnp-3317	245	68	,	,	PUNCT
fnp-3317	245	69	&	&	CCONJ
fnp-3317	245	70	goedert	goedert	PROPN
fnp-3317	245	71	,	,	PUNCT
fnp-3317	245	72	m.	m.	NOUN
fnp-3317	245	73	(	(	PUNCT
fnp-3317	245	74	2020	2020	NUM
fnp-3317	245	75	)	)	PUNCT
fnp-3317	245	76	.	.	PUNCT
fnp-3317	246	1	structures	structure	NOUN
fnp-3317	246	2	of	of	ADP
fnp-3317	246	3	α	α	NOUN
fnp-3317	246	4	-	-	PUNCT
fnp-3317	246	5	synuclein	synuclein	ADJ
fnp-3317	246	6	filaments	filament	NOUN
fnp-3317	246	7	from	from	ADP
fnp-3317	246	8	multiple	multiple	ADJ
fnp-3317	246	9	system	system	NOUN
fnp-3317	246	10	atrophy	atrophy	NOUN
fnp-3317	246	11	.	.	PUNCT
fnp-3317	247	1	nature	nature	NOUN
fnp-3317	247	2	,	,	PUNCT
fnp-3317	247	3	585(7825	585(7825	NUM
fnp-3317	247	4	)	)	PUNCT
fnp-3317	247	5	,	,	PUNCT
fnp-3317	247	6	464–469	464–469	NUM
fnp-3317	247	7	.	.	PUNCT
fnp-3317	248	1	https://doi.org/10.1038/s41586-020-2317-6	https://doi.org/10.1038/s41586-020-2317-6	NUM
fnp-3317	248	2	suárez	suárez	NOUN
fnp-3317	248	3	-	-	PUNCT
fnp-3317	248	4	calvet	calvet	NOUN
fnp-3317	248	5	,	,	PUNCT
fnp-3317	248	6	m.	m.	NOUN
fnp-3317	248	7	,	,	PUNCT
fnp-3317	248	8	karikari	karikari	NOUN
fnp-3317	248	9	,	,	PUNCT
fnp-3317	248	10	t.	t.	PROPN
fnp-3317	248	11	k.	k.	PROPN
fnp-3317	248	12	,	,	PUNCT
fnp-3317	248	13	ashton	ashton	PROPN
fnp-3317	248	14	,	,	PUNCT
fnp-3317	248	15	n.	n.	PROPN
fnp-3317	248	16	j.	j.	PROPN
fnp-3317	248	17	,	,	PUNCT
fnp-3317	248	18	lantero	lantero	PROPN
fnp-3317	248	19	rodríguez	rodríguez	PROPN
fnp-3317	248	20	,	,	PUNCT
fnp-3317	248	21	j.	j.	PROPN
fnp-3317	248	22	,	,	PUNCT
fnp-3317	248	23	milà	milà	ADJ
fnp-3317	248	24	-	-	PUNCT
fnp-3317	248	25	alomà	alomà	ADJ
fnp-3317	248	26	,	,	PUNCT
fnp-3317	248	27	m.	m.	NOUN
fnp-3317	248	28	,	,	PUNCT
fnp-3317	248	29	gispert	gispert	PROPN
fnp-3317	248	30	,	,	PUNCT
fnp-3317	248	31	j.	j.	PROPN
fnp-3317	248	32	d.	d.	PROPN
fnp-3317	248	33	,	,	PUNCT
fnp-3317	248	34	salvadó	salvadó	VERB
fnp-3317	248	35	,	,	PUNCT
fnp-3317	248	36	g.	g.	NOUN
fnp-3317	248	37	,	,	PUNCT
fnp-3317	248	38	minguillon	minguillon	NOUN
fnp-3317	248	39	,	,	PUNCT
fnp-3317	248	40	c.	c.	NOUN
fnp-3317	248	41	,	,	PUNCT
fnp-3317	248	42	fauria	fauria	PROPN
fnp-3317	248	43	,	,	PUNCT
fnp-3317	248	44	k.	k.	PROPN
fnp-3317	248	45	,	,	PUNCT
fnp-3317	248	46	shekari	shekari	PROPN
fnp-3317	248	47	,	,	PUNCT
fnp-3317	248	48	m.	m.	NOUN
fnp-3317	248	49	,	,	PUNCT
fnp-3317	248	50	grau	grau	PROPN
fnp-3317	248	51	-	-	PUNCT
fnp-3317	248	52	rivera	rivera	PROPN
fnp-3317	248	53	,	,	PUNCT
fnp-3317	248	54	o.	o.	PROPN
fnp-3317	248	55	,	,	PUNCT
fnp-3317	248	56	arenaza	arenaza	NOUN
fnp-3317	248	57	-	-	PUNCT
fnp-3317	248	58	urquijo	urquijo	NOUN
fnp-3317	248	59	,	,	PUNCT
fnp-3317	248	60	e.	e.	PROPN
fnp-3317	248	61	m.	m.	PROPN
fnp-3317	248	62	,	,	PUNCT
fnp-3317	248	63	sala	sala	PROPN
fnp-3317	248	64	-	-	PUNCT
fnp-3317	248	65	vila	vila	PROPN
fnp-3317	248	66	,	,	PUNCT
fnp-3317	248	67	a.	a.	NOUN
fnp-3317	248	68	,	,	PUNCT
fnp-3317	248	69	sánchez	sánchez	NOUN
fnp-3317	248	70	-	-	PUNCT
fnp-3317	248	71	benavides	benavide	NOUN
fnp-3317	248	72	,	,	PUNCT
fnp-3317	248	73	g.	g.	PROPN
fnp-3317	248	74	,	,	PUNCT
fnp-3317	248	75	gonzález	gonzález	PROPN
fnp-3317	248	76	-	-	PUNCT
fnp-3317	248	77	de	de	NOUN
fnp-3317	248	78	-	-	NOUN
fnp-3317	248	79	echávarri	echávarri	NOUN
fnp-3317	248	80	,	,	PUNCT
fnp-3317	248	81	j.	j.	PROPN
fnp-3317	248	82	m.	m.	PROPN
fnp-3317	248	83	,	,	PUNCT
fnp-3317	248	84	kollmorgen	kollmorgen	PROPN
fnp-3317	248	85	,	,	PUNCT
fnp-3317	248	86	g.	g.	PROPN
fnp-3317	248	87	,	,	PUNCT
fnp-3317	248	88	stoops	stoop	NOUN
fnp-3317	248	89	,	,	PUNCT
fnp-3317	248	90	e.	e.	PROPN
fnp-3317	248	91	,	,	PUNCT
fnp-3317	248	92	vanmechelen	vanmechelen	PROPN
fnp-3317	248	93	,	,	PUNCT
fnp-3317	248	94	e.	e.	PROPN
fnp-3317	248	95	,	,	PUNCT
fnp-3317	248	96	zetterberg	zetterberg	PROPN
fnp-3317	248	97	,	,	PUNCT
fnp-3317	248	98	h.	h.	PROPN
fnp-3317	248	99	,	,	PUNCT
fnp-3317	248	100	…	…	PUNCT
fnp-3317	248	101	alfa	alfa	NOUN
fnp-3317	248	102	study	study	NOUN
fnp-3317	248	103	.	.	PUNCT
fnp-3317	249	1	(	(	PUNCT
fnp-3317	249	2	2020	2020	NUM
fnp-3317	249	3	)	)	PUNCT
fnp-3317	249	4	.	.	PUNCT
fnp-3317	250	1	novel	novel	NOUN
fnp-3317	250	2	tau	tau	PROPN
fnp-3317	250	3	biomarkers	biomarker	NOUN
fnp-3317	250	4	phosphorylated	phosphorylate	VERB
fnp-3317	250	5	at	at	ADP
fnp-3317	250	6	t181	t181	NUM
fnp-3317	250	7	,	,	PUNCT
fnp-3317	250	8	t217	t217	PROPN
fnp-3317	250	9	or	or	CCONJ
fnp-3317	250	10	t231	t231	PROPN
fnp-3317	250	11	rise	rise	VERB
fnp-3317	250	12	in	in	ADP
fnp-3317	250	13	the	the	DET
fnp-3317	250	14	initial	initial	ADJ
fnp-3317	250	15	stages	stage	NOUN
fnp-3317	250	16	of	of	ADP
fnp-3317	250	17	the	the	DET
fnp-3317	250	18	preclinical	preclinical	ADJ
fnp-3317	250	19	alzheimer	alzheimer	PROPN
fnp-3317	250	20	’s	’s	PART
fnp-3317	250	21	continuum	continuum	ADJ
fnp-3317	250	22	when	when	SCONJ
fnp-3317	250	23	only	only	ADV
fnp-3317	250	24	subtle	subtle	ADJ
fnp-3317	250	25	changes	change	NOUN
fnp-3317	250	26	in	in	ADP
fnp-3317	250	27	aβ	aβ	DET
fnp-3317	250	28	pathology	pathology	NOUN
fnp-3317	250	29	are	be	AUX
fnp-3317	250	30	detected	detect	VERB
fnp-3317	250	31	.	.	PUNCT
fnp-3317	251	1	embo	embo	NOUN
fnp-3317	251	2	molecular	molecular	ADJ
fnp-3317	251	3	medicine	medicine	NOUN
fnp-3317	251	4	,	,	PUNCT
fnp-3317	251	5	12(12	12(12	NUM
fnp-3317	251	6	)	)	PUNCT
fnp-3317	251	7	,	,	PUNCT
fnp-3317	251	8	e12921	e12921	PROPN
fnp-3317	251	9	.	.	PROPN
fnp-3317	251	10	https://doi.org/10.15252/emmm.202012921	https://doi.org/10.15252/emmm.202012921	VERB
fnp-3317	251	11	wesseling	wesseling	NOUN
fnp-3317	251	12	,	,	PUNCT
fnp-3317	251	13	h.	h.	PROPN
fnp-3317	251	14	,	,	PUNCT
fnp-3317	251	15	mair	mair	PROPN
fnp-3317	251	16	,	,	PUNCT
fnp-3317	251	17	w.	w.	PROPN
fnp-3317	251	18	,	,	PUNCT
fnp-3317	251	19	kumar	kumar	PROPN
fnp-3317	251	20	,	,	PUNCT
fnp-3317	251	21	m.	m.	NOUN
fnp-3317	251	22	,	,	PUNCT
fnp-3317	251	23	schlaffner	schlaffner	NOUN
fnp-3317	251	24	,	,	PUNCT
fnp-3317	251	25	c.	c.	PROPN
fnp-3317	251	26	n.	n.	PROPN
fnp-3317	251	27	,	,	PUNCT
fnp-3317	251	28	tang	tang	PROPN
fnp-3317	251	29	,	,	PUNCT
fnp-3317	251	30	s.	s.	PROPN
fnp-3317	251	31	,	,	PUNCT
fnp-3317	251	32	beerepoot	beerepoot	PROPN
fnp-3317	251	33	,	,	PUNCT
fnp-3317	251	34	p.	p.	NOUN
fnp-3317	251	35	,	,	PUNCT
fnp-3317	251	36	fatou	fatou	NOUN
fnp-3317	251	37	,	,	PUNCT
fnp-3317	251	38	b.	b.	NOUN
fnp-3317	251	39	,	,	PUNCT
fnp-3317	251	40	guise	guise	ADJ
fnp-3317	251	41	,	,	PUNCT
fnp-3317	251	42	a.	a.	NOUN
fnp-3317	251	43	j.	j.	PROPN
fnp-3317	251	44	,	,	PUNCT
fnp-3317	251	45	cheng	cheng	PROPN
fnp-3317	251	46	,	,	PUNCT
fnp-3317	251	47	l.	l.	PROPN
fnp-3317	251	48	,	,	PUNCT
fnp-3317	251	49	takeda	takeda	PROPN
fnp-3317	251	50	,	,	PUNCT
fnp-3317	251	51	s.	s.	PROPN
fnp-3317	251	52	,	,	PUNCT
fnp-3317	251	53	muntel	muntel	PROPN
fnp-3317	251	54	,	,	PUNCT
fnp-3317	251	55	j.	j.	PROPN
fnp-3317	251	56	,	,	PUNCT
fnp-3317	251	57	rotunno	rotunno	NOUN
fnp-3317	251	58	,	,	PUNCT
fnp-3317	251	59	m.	m.	NOUN
fnp-3317	251	60	s.	s.	PROPN
fnp-3317	251	61	,	,	PUNCT
fnp-3317	251	62	dujardin	dujardin	PROPN
fnp-3317	251	63	,	,	PUNCT
fnp-3317	251	64	s.	s.	PROPN
fnp-3317	251	65	,	,	PUNCT
fnp-3317	251	66	davies	davy	NOUN
fnp-3317	251	67	,	,	PUNCT
fnp-3317	251	68	p.	p.	PROPN
fnp-3317	251	69	,	,	PUNCT
fnp-3317	251	70	kosik	kosik	PROPN
fnp-3317	251	71	,	,	PUNCT
fnp-3317	251	72	k.	k.	PROPN
fnp-3317	251	73	s.	s.	PROPN
fnp-3317	251	74	,	,	PUNCT
fnp-3317	251	75	miller	miller	PROPN
fnp-3317	251	76	,	,	PUNCT
fnp-3317	251	77	b.	b.	PROPN
fnp-3317	251	78	l.	l.	PROPN
fnp-3317	251	79	,	,	PUNCT
fnp-3317	251	80	berretta	berretta	PROPN
fnp-3317	251	81	,	,	PUNCT
fnp-3317	251	82	s.	s.	PROPN
fnp-3317	251	83	,	,	PUNCT
fnp-3317	251	84	hedreen	hedreen	PROPN
fnp-3317	251	85	,	,	PUNCT
fnp-3317	251	86	j.	j.	PROPN
fnp-3317	251	87	c.	c.	PROPN
fnp-3317	251	88	,	,	PUNCT
fnp-3317	251	89	grinberg	grinberg	PROPN
fnp-3317	251	90	,	,	PUNCT
fnp-3317	251	91	l.	l.	PROPN
fnp-3317	251	92	t.	t.	PROPN
fnp-3317	251	93	,	,	PUNCT
fnp-3317	251	94	…	…	PUNCT
fnp-3317	251	95	steen	steen	PROPN
fnp-3317	251	96	,	,	PUNCT
fnp-3317	251	97	j.	j.	PROPN
fnp-3317	251	98	a.	a.	PROPN
fnp-3317	251	99	(	(	PUNCT
fnp-3317	251	100	2020	2020	NUM
fnp-3317	251	101	)	)	PUNCT
fnp-3317	251	102	.	.	PUNCT
fnp-3317	252	1	tau	tau	PROPN
fnp-3317	252	2	ptm	ptm	PROPN
fnp-3317	252	3	profiles	profile	NOUN
fnp-3317	252	4	identify	identify	VERB
fnp-3317	252	5	patient	patient	ADJ
fnp-3317	252	6	heterogeneity	heterogeneity	NOUN
fnp-3317	252	7	and	and	CCONJ
fnp-3317	252	8	stages	stage	NOUN
fnp-3317	252	9	of	of	ADP
fnp-3317	252	10	alzheimer	alzheimer	PROPN
fnp-3317	252	11	’s	’s	PART
fnp-3317	252	12	disease	disease	NOUN
fnp-3317	252	13	.	.	PUNCT
fnp-3317	253	1	cell	cell	NOUN
fnp-3317	253	2	,	,	PUNCT
fnp-3317	253	3	183(6	183(6	NUM
fnp-3317	253	4	)	)	PUNCT
fnp-3317	253	5	,	,	PUNCT
fnp-3317	253	6	1699	1699	NUM
fnp-3317	253	7	-	-	SYM
fnp-3317	253	8	1713.e13	1713.e13	NUM
fnp-3317	253	9	.	.	PUNCT
fnp-3317	254	1	https://doi.org/10.1016/j.cell.2020.10.029	https://doi.org/10.1016/j.cell.2020.10.029	NOUN
fnp-3317	254	2	wingo	wingo	PROPN
fnp-3317	254	3	,	,	PUNCT
fnp-3317	254	4	a.	a.	NOUN
fnp-3317	254	5	p.	p.	PROPN
fnp-3317	254	6	,	,	PUNCT
fnp-3317	254	7	fan	fan	PROPN
fnp-3317	254	8	,	,	PUNCT
fnp-3317	254	9	w.	w.	PROPN
fnp-3317	254	10	,	,	PUNCT
fnp-3317	254	11	duong	duong	PROPN
fnp-3317	254	12	,	,	PUNCT
fnp-3317	254	13	d.	d.	PROPN
fnp-3317	254	14	m.	m.	NOUN
fnp-3317	254	15	,	,	PUNCT
fnp-3317	254	16	gerasimov	gerasimov	VERB
fnp-3317	254	17	,	,	PUNCT
fnp-3317	254	18	e.	e.	PROPN
fnp-3317	254	19	s.	s.	PROPN
fnp-3317	254	20	,	,	PUNCT
fnp-3317	254	21	dammer	dammer	PROPN
fnp-3317	254	22	,	,	PUNCT
fnp-3317	254	23	e.	e.	PROPN
fnp-3317	254	24	b.	b.	PROPN
fnp-3317	254	25	,	,	PUNCT
fnp-3317	254	26	liu	liu	PROPN
fnp-3317	254	27	,	,	PUNCT
fnp-3317	254	28	y.	y.	PROPN
fnp-3317	254	29	,	,	PUNCT
fnp-3317	254	30	harerimana	harerimana	PROPN
fnp-3317	254	31	,	,	PUNCT
fnp-3317	254	32	n.	n.	PROPN
fnp-3317	254	33	v.	v.	PROPN
fnp-3317	254	34	,	,	PUNCT
fnp-3317	254	35	white	white	PROPN
fnp-3317	254	36	,	,	PUNCT
fnp-3317	254	37	b.	b.	PROPN
fnp-3317	254	38	,	,	PUNCT
fnp-3317	254	39	thambisetty	thambisetty	PROPN
fnp-3317	254	40	,	,	PUNCT
fnp-3317	254	41	m.	m.	NOUN
fnp-3317	254	42	,	,	PUNCT
fnp-3317	254	43	troncoso	troncoso	PROPN
fnp-3317	254	44	,	,	PUNCT
fnp-3317	254	45	j.	j.	PROPN
fnp-3317	254	46	c.	c.	PROPN
fnp-3317	254	47	,	,	PUNCT
fnp-3317	254	48	kim	kim	PROPN
fnp-3317	254	49	,	,	PUNCT
fnp-3317	254	50	n.	n.	PROPN
fnp-3317	254	51	,	,	PUNCT
fnp-3317	254	52	schneider	schneider	PROPN
fnp-3317	254	53	,	,	PUNCT
fnp-3317	254	54	j.	j.	PROPN
fnp-3317	254	55	a.	a.	PROPN
fnp-3317	254	56	,	,	PUNCT
fnp-3317	254	57	hajjar	hajjar	PROPN
fnp-3317	254	58	,	,	PUNCT
fnp-3317	254	59	i.	i.	NOUN
fnp-3317	254	60	m.	m.	PROPN
fnp-3317	254	61	,	,	PUNCT
fnp-3317	254	62	lah	lah	PROPN
fnp-3317	254	63	,	,	PUNCT
fnp-3317	254	64	j.	j.	PROPN
fnp-3317	254	65	j.	j.	PROPN
fnp-3317	254	66	,	,	PUNCT
fnp-3317	254	67	bennett	bennett	PROPN
fnp-3317	254	68	,	,	PUNCT
fnp-3317	254	69	d.	d.	PROPN
fnp-3317	254	70	a.	a.	PROPN
fnp-3317	254	71	,	,	PUNCT
fnp-3317	254	72	seyfried	seyfrie	VERB
fnp-3317	254	73	,	,	PUNCT
fnp-3317	254	74	n.	n.	PROPN
fnp-3317	254	75	t.	t.	PROPN
fnp-3317	254	76	,	,	PUNCT
fnp-3317	254	77	levey	levey	PROPN
fnp-3317	254	78	,	,	PUNCT
fnp-3317	254	79	a.	a.	NOUN
fnp-3317	254	80	i.	i.	PROPN
fnp-3317	254	81	,	,	PUNCT
fnp-3317	254	82	&	&	CCONJ
fnp-3317	254	83	wingo	wingo	PROPN
fnp-3317	254	84	,	,	PUNCT
fnp-3317	254	85	t.	t.	PROPN
fnp-3317	254	86	s.	s.	PROPN
fnp-3317	254	87	(	(	PUNCT
fnp-3317	254	88	2020	2020	NUM
fnp-3317	254	89	)	)	PUNCT
fnp-3317	254	90	.	.	PUNCT
fnp-3317	255	1	shared	share	VERB
fnp-3317	255	2	proteomic	proteomic	ADJ
fnp-3317	255	3	effects	effect	NOUN
fnp-3317	255	4	of	of	ADP
fnp-3317	255	5	cerebral	cerebral	ADJ
fnp-3317	255	6	atherosclerosis	atherosclerosis	NOUN
fnp-3317	255	7	and	and	CCONJ
fnp-3317	255	8	alzheimer	alzheimer	PROPN
fnp-3317	255	9	’s	’s	PART
fnp-3317	255	10	disease	disease	NOUN
fnp-3317	255	11	on	on	ADP
fnp-3317	255	12	the	the	DET
fnp-3317	255	13	human	human	ADJ
fnp-3317	255	14	brain	brain	NOUN
fnp-3317	255	15	.	.	PUNCT
fnp-3317	256	1	nature	nature	NOUN
fnp-3317	256	2	neuroscience	neuroscience	NOUN
fnp-3317	256	3	,	,	PUNCT
fnp-3317	256	4	23(6	23(6	NUM
fnp-3317	256	5	)	)	PUNCT
fnp-3317	256	6	,	,	PUNCT
fnp-3317	256	7	696–700	696–700	NUM
fnp-3317	256	8	.	.	PUNCT
fnp-3317	257	1	https://doi.org/10.1038/s41593-020-0635-5	https://doi.org/10.1038/s41593-020-0635-5	NUM
fnp-3317	257	2	zhang	zhang	PROPN
fnp-3317	257	3	,	,	PUNCT
fnp-3317	257	4	w.	w.	PROPN
fnp-3317	257	5	,	,	PUNCT
fnp-3317	257	6	tarutani	tarutani	PROPN
fnp-3317	257	7	,	,	PUNCT
fnp-3317	257	8	a.	a.	PROPN
fnp-3317	257	9	,	,	PUNCT
fnp-3317	257	10	newell	newell	PROPN
fnp-3317	257	11	,	,	PUNCT
fnp-3317	257	12	k.	k.	PROPN
fnp-3317	257	13	l.	l.	PROPN
fnp-3317	257	14	,	,	PUNCT
fnp-3317	257	15	murzin	murzin	PROPN
fnp-3317	257	16	,	,	PUNCT
fnp-3317	257	17	a.	a.	NOUN
fnp-3317	257	18	g.	g.	PROPN
fnp-3317	257	19	,	,	PUNCT
fnp-3317	257	20	matsubara	matsubara	NOUN
fnp-3317	257	21	,	,	PUNCT
fnp-3317	257	22	t.	t.	PROPN
fnp-3317	257	23	,	,	PUNCT
fnp-3317	257	24	falcon	falcon	PROPN
fnp-3317	257	25	,	,	PUNCT
fnp-3317	257	26	b.	b.	PROPN
fnp-3317	257	27	,	,	PUNCT
fnp-3317	257	28	vidal	vidal	PROPN
fnp-3317	257	29	,	,	PUNCT
fnp-3317	257	30	r.	r.	PROPN
fnp-3317	257	31	,	,	PUNCT
fnp-3317	257	32	garringer	garringer	NOUN
fnp-3317	257	33	,	,	PUNCT
fnp-3317	257	34	h.	h.	PROPN
fnp-3317	257	35	j.	j.	PROPN
fnp-3317	257	36	,	,	PUNCT
fnp-3317	257	37	shi	shi	PROPN
fnp-3317	257	38	,	,	PUNCT
fnp-3317	257	39	y.	y.	PROPN
fnp-3317	257	40	,	,	PUNCT
fnp-3317	257	41	ikeuchi	ikeuchi	PROPN
fnp-3317	257	42	,	,	PUNCT
fnp-3317	257	43	t.	t.	PROPN
fnp-3317	257	44	,	,	PUNCT
fnp-3317	257	45	murayama	murayama	PROPN
fnp-3317	257	46	,	,	PUNCT
fnp-3317	257	47	s.	s.	PROPN
fnp-3317	257	48	,	,	PUNCT
fnp-3317	257	49	ghetti	ghetti	PROPN
fnp-3317	257	50	,	,	PUNCT
fnp-3317	257	51	b.	b.	PROPN
fnp-3317	257	52	,	,	PUNCT
fnp-3317	257	53	hasegawa	hasegawa	PROPN
fnp-3317	257	54	,	,	PUNCT
fnp-3317	257	55	m.	m.	NOUN
fnp-3317	257	56	,	,	PUNCT
fnp-3317	257	57	goedert	goedert	NOUN
fnp-3317	257	58	,	,	PUNCT
fnp-3317	257	59	m.	m.	NOUN
fnp-3317	257	60	,	,	PUNCT
fnp-3317	257	61	&	&	CCONJ
fnp-3317	257	62	scheres	schere	NOUN
fnp-3317	257	63	,	,	PUNCT
fnp-3317	257	64	s.	s.	PROPN
fnp-3317	257	65	h.	h.	PROPN
fnp-3317	257	66	w.	w.	PROPN
fnp-3317	257	67	(	(	PUNCT
fnp-3317	257	68	2020	2020	NUM
fnp-3317	257	69	)	)	PUNCT
fnp-3317	257	70	.	.	PUNCT
fnp-3317	258	1	novel	novel	PROPN
fnp-3317	258	2	tau	tau	PROPN
fnp-3317	258	3	filament	filament	NOUN
fnp-3317	258	4	fold	fold	NOUN
fnp-3317	258	5	in	in	ADP
fnp-3317	258	6	corticobasal	corticobasal	NOUN
fnp-3317	258	7	degeneration	degeneration	NOUN
fnp-3317	258	8	.	.	PUNCT
fnp-3317	259	1	nature	nature	NOUN
fnp-3317	259	2	,	,	PUNCT
fnp-3317	259	3	580(7802	580(7802	NOUN
fnp-3317	259	4	)	)	PUNCT
fnp-3317	259	5	,	,	PUNCT
fnp-3317	259	6	283–287	283–287	NUM
fnp-3317	259	7	.	.	PUNCT
fnp-3317	260	1	https://doi.org/10.1038/s41586-020-2043-0	https://doi.org/10.1038/s41586-020-2043-0	NUM
fnp-3317	260	2	copyright	copyright	NOUN
fnp-3317	260	3	:	:	PUNCT
fnp-3317	260	4	©	©	PROPN
fnp-3317	260	5	2021	2021	NUM
fnp-3317	260	6	the	the	DET
fnp-3317	260	7	author(s	author(s	NOUN
fnp-3317	260	8	)	)	PUNCT
fnp-3317	260	9	.	.	PUNCT
fnp-3317	261	1	this	this	PRON
fnp-3317	261	2	is	be	AUX
fnp-3317	261	3	an	an	DET
fnp-3317	261	4	open	open	ADJ
fnp-3317	261	5	access	access	NOUN
fnp-3317	261	6	article	article	NOUN
fnp-3317	261	7	distributed	distribute	VERB
fnp-3317	261	8	under	under	ADP
fnp-3317	261	9	the	the	DET
fnp-3317	261	10	terms	term	NOUN
fnp-3317	261	11	of	of	ADP
fnp-3317	261	12	the	the	DET
fnp-3317	261	13	creative	creative	ADJ
fnp-3317	261	14	commons	common	NOUN
fnp-3317	261	15	attribution	attribution	NOUN
fnp-3317	261	16	4.0	4.0	NUM
fnp-3317	261	17	international	international	ADJ
fnp-3317	261	18	license	license	NOUN
fnp-3317	261	19	(	(	PUNCT
fnp-3317	261	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3317	261	21	)	)	PUNCT
fnp-3317	261	22	,	,	PUNCT
fnp-3317	261	23	which	which	PRON
fnp-3317	261	24	permits	permit	VERB
fnp-3317	261	25	unrestricted	unrestricted	ADJ
fnp-3317	261	26	use	use	NOUN
fnp-3317	261	27	,	,	PUNCT
fnp-3317	261	28	distribution	distribution	NOUN
fnp-3317	261	29	,	,	PUNCT
fnp-3317	261	30	and	and	CCONJ
fnp-3317	261	31	reproduction	reproduction	NOUN
fnp-3317	261	32	in	in	ADP
fnp-3317	261	33	any	any	DET
fnp-3317	261	34	medium	medium	NOUN
fnp-3317	261	35	,	,	PUNCT
fnp-3317	261	36	provided	provide	VERB
fnp-3317	261	37	the	the	DET
fnp-3317	261	38	original	original	ADJ
fnp-3317	261	39	author	author	NOUN
fnp-3317	261	40	and	and	CCONJ
fnp-3317	261	41	source	source	NOUN
fnp-3317	261	42	are	be	AUX
fnp-3317	261	43	credited	credit	VERB
fnp-3317	261	44	,	,	PUNCT
fnp-3317	261	45	a	a	DET
fnp-3317	261	46	link	link	NOUN
fnp-3317	261	47	to	to	ADP
fnp-3317	261	48	the	the	DET
fnp-3317	261	49	creative	creative	ADJ
fnp-3317	261	50	commons	common	NOUN
fnp-3317	261	51	license	license	NOUN
fnp-3317	261	52	is	be	AUX
fnp-3317	261	53	provided	provide	VERB
fnp-3317	261	54	,	,	PUNCT
fnp-3317	261	55	and	and	CCONJ
fnp-3317	261	56	any	any	DET
fnp-3317	261	57	changes	change	NOUN
fnp-3317	261	58	are	be	AUX
fnp-3317	261	59	indicated	indicate	VERB
fnp-3317	261	60	.	.	PUNCT
fnp-3317	262	1	the	the	DET
fnp-3317	262	2	creative	creative	ADJ
fnp-3317	262	3	commons	common	NOUN
fnp-3317	262	4	public	public	ADJ
fnp-3317	262	5	domain	domain	NOUN
fnp-3317	262	6	dedication	dedication	NOUN
fnp-3317	262	7	waiver	waiver	NOUN
fnp-3317	262	8	(	(	PUNCT
fnp-3317	262	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3317	262	10	)	)	PUNCT
fnp-3317	262	11	applies	apply	VERB
fnp-3317	262	12	to	to	ADP
fnp-3317	262	13	the	the	DET
fnp-3317	262	14	data	datum	NOUN
fnp-3317	262	15	made	make	VERB
fnp-3317	262	16	available	available	ADJ
fnp-3317	262	17	in	in	ADP
fnp-3317	262	18	this	this	DET
fnp-3317	262	19	article	article	NOUN
fnp-3317	262	20	,	,	PUNCT
fnp-3317	262	21	unless	unless	SCONJ
fnp-3317	262	22	otherwise	otherwise	ADV
fnp-3317	262	23	stated	state	VERB
fnp-3317	262	24	.	.	PUNCT