id	sid	tid	token	lemma	pos
fnp-3326	1	1	specific	specific	ADJ
fnp-3326	1	2	immune	immune	ADJ
fnp-3326	1	3	modulation	modulation	NOUN
fnp-3326	1	4	of	of	ADP
fnp-3326	1	5	experimental	experimental	ADJ
fnp-3326	1	6	colitis	colitis	NOUN
fnp-3326	1	7	drives	drive	NOUN
fnp-3326	1	8	enteric	enteric	ADJ
fnp-3326	1	9	alpha	alpha	NOUN
fnp-3326	1	10	-	-	PUNCT
fnp-3326	1	11	synuclein	synuclein	NOUN
fnp-3326	1	12	accumulation	accumulation	NOUN
fnp-3326	1	13	and	and	CCONJ
fnp-3326	1	14	triggers	trigger	VERB
fnp-3326	1	15	age	age	NOUN
fnp-3326	1	16	-	-	PUNCT
fnp-3326	1	17	related	relate	VERB
fnp-3326	1	18	parkinson	parkinson	NOUN
fnp-3326	1	19	-	-	PUNCT
fnp-3326	1	20	like	like	ADJ
fnp-3326	1	21	brain	brain	NOUN
fnp-3326	1	22	pathology	pathology	NOUN
fnp-3326	1	23	feel	feel	VERB
fnp-3326	1	24	free	free	ADJ
fnp-3326	1	25	to	to	PART
fnp-3326	1	26	add	add	VERB
fnp-3326	1	27	comments	comment	NOUN
fnp-3326	1	28	by	by	ADP
fnp-3326	1	29	clicking	click	VERB
fnp-3326	1	30	these	these	DET
fnp-3326	1	31	icons	icon	NOUN
fnp-3326	1	32	on	on	ADP
fnp-3326	1	33	the	the	DET
fnp-3326	1	34	sidebar	sidebar	NOUN
fnp-3326	1	35	free	free	ADJ
fnp-3326	1	36	neuropathology	neuropathology	NOUN
fnp-3326	1	37	2:13	2:13	NUM
fnp-3326	1	38	(	(	PUNCT
fnp-3326	1	39	2021	2021	NUM
fnp-3326	1	40	)	)	PUNCT
fnp-3326	1	41	original	original	ADJ
fnp-3326	1	42	paper	paper	NOUN
fnp-3326	1	43	specific	specific	ADJ
fnp-3326	1	44	immune	immune	ADJ
fnp-3326	1	45	modulation	modulation	NOUN
fnp-3326	1	46	of	of	ADP
fnp-3326	1	47	experimental	experimental	ADJ
fnp-3326	1	48	colitis	colitis	NOUN
fnp-3326	1	49	drives	drive	NOUN
fnp-3326	1	50	enteric	enteric	ADJ
fnp-3326	1	51	alpha	alpha	NOUN
fnp-3326	1	52	-	-	PUNCT
fnp-3326	1	53	synuclein	synuclein	NOUN
fnp-3326	1	54	accumulation	accumulation	NOUN
fnp-3326	1	55	and	and	CCONJ
fnp-3326	1	56	triggers	trigger	VERB
fnp-3326	1	57	age	age	NOUN
fnp-3326	1	58	-	-	PUNCT
fnp-3326	1	59	related	relate	VERB
fnp-3326	1	60	parkinson	parkinson	NOUN
fnp-3326	1	61	-	-	PUNCT
fnp-3326	1	62	like	like	ADJ
fnp-3326	1	63	brain	brain	NOUN
fnp-3326	1	64	pathology	pathology	PROPN
fnp-3326	1	65	stefan	stefan	PROPN
fnp-3326	1	66	grathwohla	grathwohla	PROPN
fnp-3326	1	67	,	,	PUNCT
fnp-3326	1	68	emmanuel	emmanuel	PROPN
fnp-3326	1	69	quansahb	quansahb	PROPN
fnp-3326	1	70	,	,	PUNCT
fnp-3326	1	71	nazia	nazia	PROPN
fnp-3326	1	72	maroofa	maroofa	PROPN
fnp-3326	1	73	,	,	PUNCT
fnp-3326	1	74	jennifer	jennifer	PROPN
fnp-3326	1	75	a.	a.	PROPN
fnp-3326	1	76	steinerb	steinerb	PROPN
fnp-3326	1	77	,	,	PUNCT
fnp-3326	1	78	liz	liz	PROPN
fnp-3326	1	79	spychera	spychera	PROPN
fnp-3326	1	80	,	,	PUNCT
fnp-3326	1	81	fethallah	fethallah	PROPN
fnp-3326	1	82	benmansourc	benmansourc	PROPN
fnp-3326	1	83	,	,	PUNCT
fnp-3326	1	84	gonzalo	gonzalo	PROPN
fnp-3326	1	85	duran	duran	PROPN
fnp-3326	1	86	-	-	PUNCT
fnp-3326	1	87	pachecod	pachecod	NOUN
fnp-3326	1	88	,	,	PUNCT
fnp-3326	1	89	juliane	juliane	NOUN
fnp-3326	1	90	siebourg	siebourg	PROPN
fnp-3326	1	91	-	-	PUNCT
fnp-3326	1	92	polsterd	polsterd	PROPN
fnp-3326	1	93	,	,	PUNCT
fnp-3326	1	94	krisztina	krisztina	PROPN
fnp-3326	1	95	oroszlan	oroszlan	ADJ
fnp-3326	1	96	-	-	PUNCT
fnp-3326	1	97	szovika	szovika	NOUN
fnp-3326	1	98	,	,	PUNCT
fnp-3326	1	99	helga	helga	PROPN
fnp-3326	1	100	remya	remya	PROPN
fnp-3326	1	101	,	,	PUNCT
fnp-3326	1	102	markus	markus	NOUN
fnp-3326	1	103	haenggia	haenggia	PROPN
fnp-3326	1	104	,	,	PUNCT
fnp-3326	1	105	marc	marc	PROPN
fnp-3326	1	106	stawiskia	stawiskia	PROPN
fnp-3326	1	107	,	,	PUNCT
fnp-3326	1	108	matthias	matthias	PROPN
fnp-3326	1	109	selhausend	selhausend	NOUN
fnp-3326	1	110	,	,	PUNCT
fnp-3326	1	111	pierre	pierre	NOUN
fnp-3326	1	112	maliverd	maliverd	NOUN
fnp-3326	1	113	,	,	PUNCT
fnp-3326	1	114	andreas	andreas	PROPN
fnp-3326	1	115	wolferte	wolferte	PROPN
fnp-3326	1	116	,	,	PUNCT
fnp-3326	1	117	thomas	thomas	PROPN
fnp-3326	1	118	emriche	emriche	PROPN
fnp-3326	1	119	,	,	PUNCT
fnp-3326	1	120	zachary	zachary	PROPN
fnp-3326	1	121	madajb	madajb	NOUN
fnp-3326	1	122	,	,	PUNCT
fnp-3326	1	123	arel	arel	PROPN
fnp-3326	1	124	sud	sud	PROPN
fnp-3326	1	125	,	,	PUNCT
fnp-3326	1	126	martha	martha	PROPN
fnp-3326	1	127	l.	l.	PROPN
fnp-3326	1	128	escobar	escobar	PROPN
fnp-3326	1	129	galvisb	galvisb	PROPN
fnp-3326	1	130	,	,	PUNCT
fnp-3326	1	131	christoph	christoph	PROPN
fnp-3326	1	132	muellerf	muellerf	PROPN
fnp-3326	1	133	,	,	PUNCT
fnp-3326	1	134	annika	annika	PROPN
fnp-3326	1	135	herrmannd	herrmannd	PROPN
fnp-3326	1	136	,	,	PUNCT
fnp-3326	1	137	patrik	patrik	PROPN
fnp-3326	1	138	brundinb	brundinb	PROPN
fnp-3326	1	139	*	*	PUNCT
fnp-3326	1	140	,	,	PUNCT
fnp-3326	1	141	and	and	CCONJ
fnp-3326	1	142	markus	markus	NOUN
fnp-3326	1	143	britschgia	britschgia	PROPN
fnp-3326	1	144	*	*	PUNCT
fnp-3326	1	145	a	a	DET
fnp-3326	1	146	roche	roche	PROPN
fnp-3326	1	147	pharma	pharma	PROPN
fnp-3326	1	148	research	research	NOUN
fnp-3326	1	149	and	and	CCONJ
fnp-3326	1	150	early	early	ADJ
fnp-3326	1	151	development	development	NOUN
fnp-3326	1	152	,	,	PUNCT
fnp-3326	1	153	neuroscience	neuroscience	NOUN
fnp-3326	1	154	and	and	CCONJ
fnp-3326	1	155	rare	rare	ADJ
fnp-3326	1	156	diseases	disease	NOUN
fnp-3326	1	157	discovery	discovery	NOUN
fnp-3326	1	158	and	and	CCONJ
fnp-3326	1	159	translational	translational	ADJ
fnp-3326	1	160	area	area	NOUN
fnp-3326	1	161	,	,	PUNCT
fnp-3326	1	162	roche	roche	PROPN
fnp-3326	1	163	innovation	innovation	PROPN
fnp-3326	1	164	center	center	PROPN
fnp-3326	1	165	basel	basel	PROPN
fnp-3326	1	166	,	,	PUNCT
fnp-3326	1	167	f.	f.	PROPN
fnp-3326	1	168	hoffmann	hoffmann	PROPN
fnp-3326	1	169	-	-	PUNCT
fnp-3326	1	170	la	la	PROPN
fnp-3326	1	171	roche	roche	PROPN
fnp-3326	1	172	ltd	ltd	PROPN
fnp-3326	1	173	,	,	PUNCT
fnp-3326	1	174	grenzacherstrasse	grenzacherstrasse	PROPN
fnp-3326	1	175	124	124	NUM
fnp-3326	1	176	,	,	PUNCT
fnp-3326	1	177	basel	basel	PROPN
fnp-3326	1	178	,	,	PUNCT
fnp-3326	1	179	switzerland	switzerland	PROPN
fnp-3326	1	180	b	b	PROPN
fnp-3326	1	181	parkinson	parkinson	NOUN
fnp-3326	1	182	’s	’s	PART
fnp-3326	1	183	disease	disease	NOUN
fnp-3326	1	184	center	center	NOUN
fnp-3326	1	185	,	,	PUNCT
fnp-3326	1	186	department	department	NOUN
fnp-3326	1	187	of	of	ADP
fnp-3326	1	188	neurodegenerative	neurodegenerative	ADJ
fnp-3326	1	189	science	science	NOUN
fnp-3326	1	190	,	,	PUNCT
fnp-3326	1	191	van	van	PROPN
fnp-3326	1	192	andel	andel	PROPN
fnp-3326	1	193	institute	institute	PROPN
fnp-3326	1	194	,	,	PUNCT
fnp-3326	1	195	333	333	NUM
fnp-3326	1	196	bostwick	bostwick	PROPN
fnp-3326	1	197	ave	ave	PROPN
fnp-3326	1	198	.	.	PUNCT
fnp-3326	2	1	ne	ne	PROPN
fnp-3326	2	2	,	,	PUNCT
fnp-3326	2	3	grand	grand	PROPN
fnp-3326	2	4	rapids	rapids	PROPN
fnp-3326	2	5	,	,	PUNCT
fnp-3326	2	6	mi	mi	PROPN
fnp-3326	2	7	,	,	PUNCT
fnp-3326	2	8	usa	usa	PROPN
fnp-3326	2	9	c	c	PROPN
fnp-3326	2	10	roche	roche	PROPN
fnp-3326	2	11	pharma	pharma	PROPN
fnp-3326	2	12	research	research	NOUN
fnp-3326	2	13	and	and	CCONJ
fnp-3326	2	14	early	early	ADJ
fnp-3326	2	15	development	development	NOUN
fnp-3326	2	16	,	,	PUNCT
fnp-3326	2	17	predi	predi	NOUN
fnp-3326	2	18	,	,	PUNCT
fnp-3326	2	19	roche	roche	PROPN
fnp-3326	2	20	innovation	innovation	PROPN
fnp-3326	2	21	center	center	PROPN
fnp-3326	2	22	basel	basel	PROPN
fnp-3326	2	23	,	,	PUNCT
fnp-3326	2	24	f.	f.	PROPN
fnp-3326	2	25	hoffmann	hoffmann	PROPN
fnp-3326	2	26	-	-	PUNCT
fnp-3326	2	27	la	la	PROPN
fnp-3326	2	28	roche	roche	PROPN
fnp-3326	2	29	ltd	ltd	PROPN
fnp-3326	2	30	,	,	PUNCT
fnp-3326	2	31	grenzacherstrasse	grenzacherstrasse	PROPN
fnp-3326	2	32	124	124	NUM
fnp-3326	2	33	,	,	PUNCT
fnp-3326	2	34	basel	basel	PROPN
fnp-3326	2	35	,	,	PUNCT
fnp-3326	2	36	switzerland	switzerland	PROPN
fnp-3326	2	37	d	d	X
fnp-3326	2	38	roche	roche	PROPN
fnp-3326	2	39	pharma	pharma	PROPN
fnp-3326	2	40	research	research	NOUN
fnp-3326	2	41	and	and	CCONJ
fnp-3326	2	42	early	early	ADJ
fnp-3326	2	43	development	development	NOUN
fnp-3326	2	44	,	,	PUNCT
fnp-3326	2	45	pharmaceutical	pharmaceutical	NOUN
fnp-3326	2	46	sciences	science	NOUN
fnp-3326	2	47	,	,	PUNCT
fnp-3326	2	48	roche	roche	NOUN
fnp-3326	2	49	innovation	innovation	PROPN
fnp-3326	2	50	center	center	PROPN
fnp-3326	2	51	basel	basel	PROPN
fnp-3326	2	52	,	,	PUNCT
fnp-3326	2	53	f.	f.	PROPN
fnp-3326	2	54	hoffmann	hoffmann	PROPN
fnp-3326	2	55	-	-	PUNCT
fnp-3326	2	56	la	la	PROPN
fnp-3326	2	57	roche	roche	PROPN
fnp-3326	2	58	ltd	ltd	PROPN
fnp-3326	2	59	,	,	PUNCT
fnp-3326	2	60	grenzacherstrasse	grenzacherstrasse	PROPN
fnp-3326	2	61	124	124	NUM
fnp-3326	2	62	,	,	PUNCT
fnp-3326	2	63	basel	basel	PROPN
fnp-3326	2	64	,	,	PUNCT
fnp-3326	2	65	switzerland	switzerland	PROPN
fnp-3326	2	66	e	e	PROPN
fnp-3326	2	67	roche	roche	PROPN
fnp-3326	2	68	pharma	pharma	PROPN
fnp-3326	2	69	research	research	NOUN
fnp-3326	2	70	and	and	CCONJ
fnp-3326	2	71	early	early	ADJ
fnp-3326	2	72	development	development	NOUN
fnp-3326	2	73	,	,	PUNCT
fnp-3326	2	74	pharmaceutical	pharmaceutical	NOUN
fnp-3326	2	75	sciences	science	NOUN
fnp-3326	2	76	,	,	PUNCT
fnp-3326	2	77	roche	roche	PROPN
fnp-3326	2	78	innovation	innovation	PROPN
fnp-3326	2	79	center	center	PROPN
fnp-3326	2	80	munich	munich	PROPN
fnp-3326	2	81	,	,	PUNCT
fnp-3326	2	82	roche	roche	PROPN
fnp-3326	2	83	diagnostics	diagnostic	NOUN
fnp-3326	2	84	gmbh	gmbh	NOUN
fnp-3326	2	85	,	,	PUNCT
fnp-3326	2	86	nonnenwald	nonnenwald	NOUN
fnp-3326	2	87	2	2	NUM
fnp-3326	2	88	,	,	PUNCT
fnp-3326	2	89	penzberg	penzberg	PROPN
fnp-3326	2	90	,	,	PUNCT
fnp-3326	2	91	germany	germany	PROPN
fnp-3326	2	92	f	f	PROPN
fnp-3326	2	93	institute	institute	PROPN
fnp-3326	2	94	of	of	ADP
fnp-3326	2	95	pathology	pathology	PROPN
fnp-3326	2	96	,	,	PUNCT
fnp-3326	2	97	university	university	PROPN
fnp-3326	2	98	of	of	ADP
fnp-3326	2	99	bern	bern	PROPN
fnp-3326	2	100	,	,	PUNCT
fnp-3326	2	101	murtenstrasse	murtenstrasse	NOUN
fnp-3326	2	102	31	31	NUM
fnp-3326	2	103	,	,	PUNCT
fnp-3326	2	104	bern	bern	PROPN
fnp-3326	2	105	,	,	PUNCT
fnp-3326	2	106	switzerland	switzerland	PROPN
fnp-3326	2	107	*	*	PUNCT
fnp-3326	2	108	corresponding	correspond	VERB
fnp-3326	2	109	authors	author	NOUN
fnp-3326	2	110	:	:	PUNCT
fnp-3326	2	111	markus	markus	PROPN
fnp-3326	2	112	britschgi	britschgi	PROPN
fnp-3326	2	113	·	·	PUNCT
fnp-3326	2	114	roche	roche	PROPN
fnp-3326	2	115	pharma	pharma	PROPN
fnp-3326	2	116	research	research	NOUN
fnp-3326	2	117	and	and	CCONJ
fnp-3326	2	118	early	early	ADJ
fnp-3326	2	119	development	development	NOUN
fnp-3326	2	120	·	·	PUNCT
fnp-3326	2	121	neuroscience	neuroscience	NOUN
fnp-3326	2	122	and	and	CCONJ
fnp-3326	2	123	rare	rare	ADJ
fnp-3326	2	124	diseases	disease	NOUN
fnp-3326	2	125	discovery	discovery	NOUN
fnp-3326	2	126	and	and	CCONJ
fnp-3326	2	127	translational	translational	ADJ
fnp-3326	2	128	area	area	NOUN
fnp-3326	2	129	·	·	PUNCT
fnp-3326	2	130	roche	roche	PROPN
fnp-3326	2	131	innovation	innovation	PROPN
fnp-3326	2	132	center	center	PROPN
fnp-3326	2	133	basel	basel	PROPN
fnp-3326	2	134	·	·	PUNCT
fnp-3326	2	135	f.	f.	PROPN
fnp-3326	2	136	hoffmann	hoffmann	PROPN
fnp-3326	2	137	-	-	PUNCT
fnp-3326	2	138	la	la	PROPN
fnp-3326	2	139	roche	roche	PROPN
fnp-3326	2	140	ltd	ltd	PROPN
fnp-3326	2	141	·	·	PUNCT
fnp-3326	2	142	grenzacherstrasse	grenzacherstrasse	VERB
fnp-3326	2	143	124	124	NUM
fnp-3326	2	144	·	·	SYM
fnp-3326	2	145	4070	4070	NUM
fnp-3326	2	146	basel	basel	PROPN
fnp-3326	2	147	·	·	PUNCT
fnp-3326	2	148	switzerland	switzerland	PROPN
fnp-3326	2	149	markus.britschgi@roche.com	markus.britschgi@roche.com	X
fnp-3326	2	150	patrik	patrik	PROPN
fnp-3326	2	151	brundin	brundin	PROPN
fnp-3326	2	152	·	·	PUNCT
fnp-3326	3	1	van	van	PROPN
fnp-3326	3	2	andel	andel	PROPN
fnp-3326	3	3	institute	institute	PROPN
fnp-3326	3	4	·	·	PROPN
fnp-3326	3	5	333	333	NUM
fnp-3326	3	6	bostwick	bostwick	PROPN
fnp-3326	3	7	ave	ave	PROPN
fnp-3326	3	8	.	.	PUNCT
fnp-3326	3	9	ne	ne	PROPN
fnp-3326	3	10	·	·	PUNCT
fnp-3326	3	11	grand	grand	ADJ
fnp-3326	3	12	rapids	rapids	PROPN
fnp-3326	3	13	·	·	PUNCT
fnp-3326	3	14	mi	mi	PROPN
fnp-3326	3	15	49503	49503	NUM
fnp-3326	3	16	·	·	SYM
fnp-3326	3	17	usa	usa	PROPN
fnp-3326	3	18	patrik.brundin@vai.orgs	patrik.brundin@vai.orgs	PROPN
fnp-3326	3	19	submitted	submit	VERB
fnp-3326	3	20	:	:	PUNCT
fnp-3326	3	21	07	07	NUM
fnp-3326	3	22	april	april	PROPN
fnp-3326	3	23	2021	2021	NUM
fnp-3326	3	24	accepted	accept	VERB
fnp-3326	3	25	:	:	PUNCT
fnp-3326	3	26	08	08	NUM
fnp-3326	3	27	may	may	AUX
fnp-3326	3	28	2021	2021	NUM
fnp-3326	3	29	copyedited	copyedit	VERB
fnp-3326	3	30	by	by	ADP
fnp-3326	3	31	:	:	PUNCT
fnp-3326	3	32	bert	bert	PROPN
fnp-3326	3	33	m.	m.	PROPN
fnp-3326	3	34	verheijen	verheijen	PROPN
fnp-3326	3	35	published	publish	VERB
fnp-3326	3	36	:	:	PUNCT
fnp-3326	3	37	18	18	NUM
fnp-3326	3	38	may	may	PROPN
fnp-3326	3	39	2021	2021	NUM
fnp-3326	3	40	https://doi.org/10.17879/freeneuropathology-2021-3326	https://doi.org/10.17879/freeneuropathology-2021-3326	CCONJ
fnp-3326	3	41	additional	additional	ADJ
fnp-3326	3	42	resources	resource	NOUN
fnp-3326	3	43	and	and	CCONJ
fnp-3326	3	44	electronic	electronic	ADJ
fnp-3326	3	45	supplementary	supplementary	ADJ
fnp-3326	3	46	material	material	NOUN
fnp-3326	3	47	:	:	PUNCT
fnp-3326	3	48	supplementary	supplementary	ADJ
fnp-3326	3	49	material	material	NOUN
fnp-3326	3	50	keywords	keyword	NOUN
fnp-3326	3	51	:	:	PUNCT
fnp-3326	3	52	alpha	alpha	NOUN
fnp-3326	3	53	-	-	PUNCT
fnp-3326	3	54	synuclein	synuclein	NOUN
fnp-3326	3	55	,	,	PUNCT
fnp-3326	3	56	experimental	experimental	ADJ
fnp-3326	3	57	colitis	colitis	NOUN
fnp-3326	3	58	,	,	PUNCT
fnp-3326	3	59	enteric	enteric	ADJ
fnp-3326	3	60	nervous	nervous	ADJ
fnp-3326	3	61	system	system	NOUN
fnp-3326	3	62	,	,	PUNCT
fnp-3326	3	63	parkinson	parkinson	NOUN
fnp-3326	3	64	’s	’s	PART
fnp-3326	3	65	disease	disease	NOUN
fnp-3326	3	66	,	,	PUNCT
fnp-3326	3	67	substantia	substantia	NOUN
fnp-3326	3	68	nigra	nigra	PROPN
fnp-3326	3	69	abstract	abstract	ADJ
fnp-3326	3	70	background	background	NOUN
fnp-3326	3	71	:	:	PUNCT
fnp-3326	3	72	in	in	ADP
fnp-3326	3	73	some	some	DET
fnp-3326	3	74	people	people	NOUN
fnp-3326	3	75	with	with	ADP
fnp-3326	3	76	parkinson	parkinson	NOUN
fnp-3326	3	77	’s	’s	PART
fnp-3326	3	78	disease	disease	NOUN
fnp-3326	3	79	(	(	PUNCT
fnp-3326	3	80	pd	pd	PROPN
fnp-3326	3	81	)	)	PUNCT
fnp-3326	3	82	,	,	PUNCT
fnp-3326	3	83	α	α	X
fnp-3326	3	84	-	-	PUNCT
fnp-3326	3	85	synuclein	synuclein	NOUN
fnp-3326	3	86	(	(	PUNCT
fnp-3326	3	87	αsyn	αsyn	PROPN
fnp-3326	3	88	)	)	PUNCT
fnp-3326	3	89	accumulation	accumulation	NOUN
fnp-3326	3	90	may	may	AUX
fnp-3326	3	91	begin	begin	VERB
fnp-3326	3	92	in	in	ADP
fnp-3326	3	93	the	the	DET
fnp-3326	3	94	enteric	enteric	ADJ
fnp-3326	3	95	nervous	nervous	ADJ
fnp-3326	3	96	system	system	NOUN
fnp-3326	3	97	(	(	PUNCT
fnp-3326	3	98	ens	en	NOUN
fnp-3326	3	99	)	)	PUNCT
fnp-3326	3	100	decades	decade	NOUN
fnp-3326	3	101	before	before	ADP
fnp-3326	3	102	development	development	NOUN
fnp-3326	3	103	of	of	ADP
fnp-3326	3	104	brain	brain	NOUN
fnp-3326	3	105	pathology	pathology	NOUN
fnp-3326	3	106	and	and	CCONJ
fnp-3326	3	107	disease	disease	NOUN
fnp-3326	3	108	diagnosis	diagnosis	NOUN
fnp-3326	3	109	.	.	PUNCT
fnp-3326	3	110	  	  	SPACE
fnp-3326	3	111	objective	objective	NOUN
fnp-3326	3	112	:	:	PUNCT
fnp-3326	3	113	to	to	PART
fnp-3326	3	114	determine	determine	VERB
fnp-3326	3	115	how	how	SCONJ
fnp-3326	3	116	different	different	ADJ
fnp-3326	3	117	types	type	NOUN
fnp-3326	3	118	and	and	CCONJ
fnp-3326	3	119	severity	severity	NOUN
fnp-3326	3	120	of	of	ADP
fnp-3326	3	121	intestinal	intestinal	ADJ
fnp-3326	3	122	inflammation	inflammation	NOUN
fnp-3326	3	123	could	could	AUX
fnp-3326	3	124	trigger	trigger	VERB
fnp-3326	3	125	αsyn	αsyn	ADJ
fnp-3326	3	126	accumulation	accumulation	NOUN
fnp-3326	3	127	in	in	ADP
fnp-3326	3	128	the	the	DET
fnp-3326	3	129	ens	ens	NOUN
fnp-3326	3	130	and	and	CCONJ
fnp-3326	3	131	the	the	DET
fnp-3326	3	132	subsequent	subsequent	ADJ
fnp-3326	3	133	development	development	NOUN
fnp-3326	3	134	of	of	ADP
fnp-3326	3	135	αsyn	αsyn	ADJ
fnp-3326	3	136	brain	brain	NOUN
fnp-3326	3	137	pathology	pathology	NOUN
fnp-3326	3	138	.	.	PUNCT
fnp-3326	3	139	  	  	SPACE
fnp-3326	4	1	methods	method	NOUN
fnp-3326	4	2	:	:	PUNCT
fnp-3326	4	3	we	we	PRON
fnp-3326	4	4	assessed	assess	VERB
fnp-3326	4	5	the	the	DET
fnp-3326	4	6	effects	effect	NOUN
fnp-3326	4	7	of	of	ADP
fnp-3326	4	8	modulating	modulate	VERB
fnp-3326	4	9	shortand	shortand	NOUN
fnp-3326	4	10	long	long	ADJ
fnp-3326	4	11	-	-	PUNCT
fnp-3326	4	12	term	term	NOUN
fnp-3326	4	13	experimental	experimental	ADJ
fnp-3326	4	14	colitis	colitis	NOUN
fnp-3326	4	15	on	on	ADP
fnp-3326	4	16	αsyn	αsyn	ADJ
fnp-3326	4	17	accumulation	accumulation	NOUN
fnp-3326	4	18	in	in	ADP
fnp-3326	4	19	the	the	DET
fnp-3326	4	20	gut	gut	NOUN
fnp-3326	4	21	of	of	ADP
fnp-3326	4	22	αsyn	αsyn	ADJ
fnp-3326	4	23	transgenic	transgenic	NOUN
fnp-3326	4	24	and	and	CCONJ
fnp-3326	4	25	wild	wild	ADJ
fnp-3326	4	26	type	type	NOUN
fnp-3326	4	27	mice	mouse	NOUN
fnp-3326	4	28	by	by	ADP
fnp-3326	4	29	immunostaining	immunostaine	VERB
fnp-3326	4	30	and	and	CCONJ
fnp-3326	4	31	gene	gene	NOUN
fnp-3326	4	32	expression	expression	NOUN
fnp-3326	4	33	analysis	analysis	NOUN
fnp-3326	4	34	.	.	PUNCT
fnp-3326	5	1	to	to	PART
fnp-3326	5	2	determine	determine	VERB
fnp-3326	5	3	the	the	DET
fnp-3326	5	4	long	long	ADJ
fnp-3326	5	5	-	-	PUNCT
fnp-3326	5	6	term	term	NOUN
fnp-3326	5	7	effect	effect	NOUN
fnp-3326	5	8	on	on	ADP
fnp-3326	5	9	the	the	DET
fnp-3326	5	10	brain	brain	NOUN
fnp-3326	5	11	,	,	PUNCT
fnp-3326	5	12	we	we	PRON
fnp-3326	5	13	induced	induce	VERB
fnp-3326	5	14	dextran	dextran	ADJ
fnp-3326	5	15	sulfate	sulfate	NOUN
fnp-3326	5	16	sodium	sodium	NOUN
fnp-3326	5	17	(	(	PUNCT
fnp-3326	5	18	dss	dss	NOUN
fnp-3326	5	19	)	)	PUNCT
fnp-3326	5	20	colitis	colitis	NOUN
fnp-3326	5	21	in	in	ADP
fnp-3326	5	22	young	young	ADJ
fnp-3326	5	23	αsyn	αsyn	ADJ
fnp-3326	5	24	transgenic	transgenic	NOUN
fnp-3326	5	25	mice	mouse	NOUN
fnp-3326	5	26	and	and	CCONJ
fnp-3326	5	27	aged	age	VERB
fnp-3326	5	28	them	they	PRON
fnp-3326	5	29	under	under	ADP
fnp-3326	5	30	normal	normal	ADJ
fnp-3326	5	31	conditions	condition	NOUN
fnp-3326	5	32	up	up	ADP
fnp-3326	5	33	to	to	ADP
fnp-3326	5	34	9	9	NUM
fnp-3326	5	35	or	or	CCONJ
fnp-3326	5	36	21	21	NUM
fnp-3326	5	37	months	month	NOUN
fnp-3326	5	38	before	before	ADP
fnp-3326	5	39	tissue	tissue	NOUN
fnp-3326	5	40	analyses	analysis	NOUN
fnp-3326	5	41	.	.	PUNCT
fnp-3326	5	42	  	  	SPACE
fnp-3326	6	1	results	result	VERB
fnp-3326	6	2	:	:	PUNCT
fnp-3326	6	3	a	a	DET
fnp-3326	6	4	single	single	ADJ
fnp-3326	6	5	strong	strong	ADJ
fnp-3326	6	6	or	or	CCONJ
fnp-3326	6	7	sustained	sustain	VERB
fnp-3326	6	8	mild	mild	ADJ
fnp-3326	6	9	dss	dss	NOUN
fnp-3326	6	10	colitis	colitis	NOUN
fnp-3326	6	11	triggered	trigger	VERB
fnp-3326	6	12	αsyn	αsyn	ADJ
fnp-3326	6	13	accumulation	accumulation	NOUN
fnp-3326	6	14	in	in	ADP
fnp-3326	6	15	the	the	DET
fnp-3326	6	16	submucosal	submucosal	NOUN
fnp-3326	6	17	plexus	plexus	NOUN
fnp-3326	6	18	of	of	ADP
fnp-3326	6	19	wild	wild	ADJ
fnp-3326	6	20	type	type	NOUN
fnp-3326	6	21	and	and	CCONJ
fnp-3326	6	22	αsyn	αsyn	ADJ
fnp-3326	6	23	transgenic	transgenic	NOUN
fnp-3326	6	24	mice	mouse	NOUN
fnp-3326	6	25	,	,	PUNCT
fnp-3326	6	26	while	while	SCONJ
fnp-3326	6	27	short	short	ADJ
fnp-3326	6	28	-	-	PUNCT
fnp-3326	6	29	term	term	NOUN
fnp-3326	6	30	mild	mild	ADJ
fnp-3326	6	31	dss	dss	NOUN
fnp-3326	6	32	colitis	colitis	NOUN
fnp-3326	6	33	or	or	CCONJ
fnp-3326	6	34	inflammation	inflammation	NOUN
fnp-3326	6	35	induced	induce	VERB
fnp-3326	6	36	by	by	ADP
fnp-3326	6	37	lipopolysaccharide	lipopolysaccharide	ADJ
fnp-3326	6	38	did	do	AUX
fnp-3326	6	39	not	not	PART
fnp-3326	6	40	have	have	VERB
fnp-3326	6	41	such	such	DET
fnp-3326	6	42	an	an	DET
fnp-3326	6	43	effect	effect	NOUN
fnp-3326	6	44	.	.	PUNCT
fnp-3326	7	1	genetic	genetic	ADJ
fnp-3326	7	2	and	and	CCONJ
fnp-3326	7	3	pharmacological	pharmacological	ADJ
fnp-3326	7	4	modulation	modulation	NOUN
fnp-3326	7	5	of	of	ADP
fnp-3326	7	6	macrophage	macrophage	NOUN
fnp-3326	7	7	-	-	PUNCT
fnp-3326	7	8	associated	associate	VERB
fnp-3326	7	9	pathways	pathway	NOUN
fnp-3326	7	10	modulated	modulate	VERB
fnp-3326	7	11	the	the	DET
fnp-3326	7	12	severity	severity	NOUN
fnp-3326	7	13	of	of	ADP
fnp-3326	7	14	enteric	enteric	ADJ
fnp-3326	7	15	αsyn	αsyn	NOUN
fnp-3326	7	16	.	.	PUNCT
fnp-3326	8	1	remarkably	remarkably	ADV
fnp-3326	8	2	,	,	PUNCT
fnp-3326	8	3	experimental	experimental	ADJ
fnp-3326	8	4	colitis	colitis	NOUN
fnp-3326	8	5	at	at	ADP
fnp-3326	8	6	three	three	NUM
fnp-3326	8	7	months	month	NOUN
fnp-3326	8	8	of	of	ADP
fnp-3326	8	9	age	age	NOUN
fnp-3326	8	10	exacerbated	exacerbate	VERB
fnp-3326	8	11	the	the	DET
fnp-3326	8	12	accumulation	accumulation	NOUN
fnp-3326	8	13	of	of	ADP
fnp-3326	8	14	aggregated	aggregate	VERB
fnp-3326	8	15	phospho	phospho	NOUN
fnp-3326	8	16	-	-	PUNCT
fnp-3326	8	17	serine	serine	NOUN
fnp-3326	8	18	129	129	NUM
fnp-3326	8	19	αsyn	αsyn	NOUN
fnp-3326	8	20	in	in	ADP
fnp-3326	8	21	the	the	DET
fnp-3326	8	22	midbrain	midbrain	NOUN
fnp-3326	8	23	(	(	PUNCT
fnp-3326	8	24	including	include	VERB
fnp-3326	8	25	the	the	DET
fnp-3326	8	26	substantia	substantia	NOUN
fnp-3326	8	27	nigra	nigra	NOUN
fnp-3326	8	28	)	)	PUNCT
fnp-3326	8	29	,	,	PUNCT
fnp-3326	8	30	in	in	ADP
fnp-3326	8	31	21but	21but	NUM
fnp-3326	8	32	not	not	PART
fnp-3326	8	33	9	9	NUM
fnp-3326	8	34	-	-	PUNCT
fnp-3326	8	35	month	month	NOUN
fnp-3326	8	36	-	-	PUNCT
fnp-3326	8	37	old	old	ADJ
fnp-3326	8	38	αsyn	αsyn	ADJ
fnp-3326	8	39	transgenic	transgenic	NOUN
fnp-3326	8	40	mice	mouse	NOUN
fnp-3326	8	41	.	.	PUNCT
fnp-3326	9	1	this	this	DET
fnp-3326	9	2	increase	increase	NOUN
fnp-3326	9	3	in	in	ADP
fnp-3326	9	4	midbrain	midbrain	NOUN
fnp-3326	9	5	αsyn	αsyn	ADJ
fnp-3326	9	6	accumulation	accumulation	NOUN
fnp-3326	9	7	is	be	AUX
fnp-3326	9	8	accompanied	accompany	VERB
fnp-3326	9	9	by	by	ADP
fnp-3326	9	10	the	the	DET
fnp-3326	9	11	loss	loss	NOUN
fnp-3326	9	12	of	of	ADP
fnp-3326	9	13	tyrosine	tyrosine	NOUN
fnp-3326	9	14	hydroxylase	hydroxylase	NOUN
fnp-3326	9	15	-	-	PUNCT
fnp-3326	9	16	immunoreactive	immunoreactive	ADJ
fnp-3326	9	17	nigral	nigral	ADJ
fnp-3326	9	18	neurons	neuron	NOUN
fnp-3326	9	19	.	.	PUNCT
fnp-3326	9	20	  	  	SPACE
fnp-3326	10	1	conclusions	conclusion	NOUN
fnp-3326	10	2	:	:	PUNCT
fnp-3326	10	3	our	our	PRON
fnp-3326	10	4	data	datum	NOUN
fnp-3326	10	5	suggest	suggest	VERB
fnp-3326	10	6	that	that	SCONJ
fnp-3326	10	7	specific	specific	ADJ
fnp-3326	10	8	types	type	NOUN
fnp-3326	10	9	and	and	CCONJ
fnp-3326	10	10	severity	severity	NOUN
fnp-3326	10	11	of	of	ADP
fnp-3326	10	12	intestinal	intestinal	ADJ
fnp-3326	10	13	inflammation	inflammation	NOUN
fnp-3326	10	14	,	,	PUNCT
fnp-3326	10	15	mediated	mediate	VERB
fnp-3326	10	16	by	by	ADP
fnp-3326	10	17	monocyte	monocyte	NOUN
fnp-3326	10	18	/	/	SYM
fnp-3326	10	19	macrophage	macrophage	ADJ
fnp-3326	10	20	signaling	signaling	NOUN
fnp-3326	10	21	,	,	PUNCT
fnp-3326	10	22	could	could	AUX
fnp-3326	10	23	play	play	VERB
fnp-3326	10	24	a	a	DET
fnp-3326	10	25	critical	critical	ADJ
fnp-3326	10	26	role	role	NOUN
fnp-3326	10	27	in	in	ADP
fnp-3326	10	28	the	the	DET
fnp-3326	10	29	initiation	initiation	NOUN
fnp-3326	10	30	and	and	CCONJ
fnp-3326	10	31	progression	progression	NOUN
fnp-3326	10	32	of	of	ADP
fnp-3326	10	33	pd	pd	PROPN
fnp-3326	10	34	.	.	PROPN
fnp-3326	10	35	introduction	introduction	NOUN
fnp-3326	10	36	parkinson	parkinson	NOUN
fnp-3326	10	37	’s	’s	PART
fnp-3326	10	38	disease	disease	NOUN
fnp-3326	10	39	(	(	PUNCT
fnp-3326	10	40	pd	pd	NOUN
fnp-3326	10	41	)	)	PUNCT
fnp-3326	10	42	is	be	AUX
fnp-3326	10	43	a	a	DET
fnp-3326	10	44	progressively	progressively	ADV
fnp-3326	10	45	debilitating	debilitate	VERB
fnp-3326	10	46	neurodegenerative	neurodegenerative	ADJ
fnp-3326	10	47	disease	disease	NOUN
fnp-3326	10	48	affecting	affect	VERB
fnp-3326	10	49	1	1	NUM
fnp-3326	10	50	%	%	NOUN
fnp-3326	10	51	of	of	ADP
fnp-3326	10	52	the	the	DET
fnp-3326	10	53	population	population	NOUN
fnp-3326	10	54	above	above	ADP
fnp-3326	10	55	60	60	NUM
fnp-3326	10	56	years	year	NOUN
fnp-3326	11	1	[	[	X
fnp-3326	11	2	1	1	NUM
fnp-3326	11	3	]	]	PUNCT
fnp-3326	11	4	.	.	PUNCT
fnp-3326	12	1	typical	typical	ADJ
fnp-3326	12	2	symptoms	symptom	NOUN
fnp-3326	12	3	are	be	AUX
fnp-3326	12	4	motor	motor	NOUN
fnp-3326	12	5	impairments	impairment	NOUN
fnp-3326	12	6	including	include	VERB
fnp-3326	12	7	muscle	muscle	NOUN
fnp-3326	12	8	rigidity	rigidity	NOUN
fnp-3326	12	9	,	,	PUNCT
fnp-3326	12	10	tremor	tremor	NOUN
fnp-3326	12	11	,	,	PUNCT
fnp-3326	12	12	and	and	CCONJ
fnp-3326	12	13	bradykinesia	bradykinesia	PROPN
fnp-3326	12	14	.	.	PUNCT
fnp-3326	13	1	neuropathologically	neuropathologically	PROPN
fnp-3326	13	2	,	,	PUNCT
fnp-3326	13	3	pd	pd	PROPN
fnp-3326	13	4	is	be	AUX
fnp-3326	13	5	hallmarked	hallmarke	VERB
fnp-3326	13	6	by	by	ADP
fnp-3326	13	7	loss	loss	NOUN
fnp-3326	13	8	of	of	ADP
fnp-3326	13	9	dopaminergic	dopaminergic	ADJ
fnp-3326	13	10	neurons	neuron	NOUN
fnp-3326	13	11	in	in	ADP
fnp-3326	13	12	the	the	DET
fnp-3326	13	13	substantia	substantia	NOUN
fnp-3326	13	14	nigra	nigra	NOUN
fnp-3326	13	15	(	(	PUNCT
fnp-3326	13	16	sn	sn	PROPN
fnp-3326	13	17	)	)	PUNCT
fnp-3326	13	18	,	,	PUNCT
fnp-3326	13	19	a	a	DET
fnp-3326	13	20	concomitant	concomitant	ADJ
fnp-3326	13	21	reduction	reduction	NOUN
fnp-3326	13	22	of	of	ADP
fnp-3326	13	23	striatal	striatal	ADJ
fnp-3326	13	24	dopaminergic	dopaminergic	ADJ
fnp-3326	13	25	signaling	signal	VERB
fnp-3326	13	26	[	[	X
fnp-3326	13	27	2	2	NUM
fnp-3326	13	28	]	]	PUNCT
fnp-3326	13	29	,	,	PUNCT
fnp-3326	13	30	and	and	CCONJ
fnp-3326	13	31	the	the	DET
fnp-3326	13	32	presence	presence	NOUN
fnp-3326	13	33	of	of	ADP
fnp-3326	13	34	intraneuronal	intraneuronal	ADJ
fnp-3326	13	35	inclusions	inclusion	NOUN
fnp-3326	13	36	called	call	VERB
fnp-3326	13	37	lewy	lewy	PROPN
fnp-3326	13	38	bodies	body	NOUN
fnp-3326	13	39	and	and	CCONJ
fnp-3326	13	40	neurites	neurite	NOUN
fnp-3326	14	1	[	[	X
fnp-3326	14	2	3	3	NUM
fnp-3326	14	3	]	]	PUNCT
fnp-3326	14	4	.	.	PUNCT
fnp-3326	15	1	lewy	lewy	PROPN
fnp-3326	15	2	pathology	pathology	PROPN
fnp-3326	15	3	is	be	AUX
fnp-3326	15	4	enriched	enrich	VERB
fnp-3326	15	5	in	in	ADP
fnp-3326	15	6	α	α	NOUN
fnp-3326	15	7	-	-	PUNCT
fnp-3326	15	8	synuclein	synuclein	NOUN
fnp-3326	15	9	(	(	PUNCT
fnp-3326	15	10	αsyn	αsyn	PROPN
fnp-3326	15	11	)	)	PUNCT
fnp-3326	15	12	,	,	PUNCT
fnp-3326	15	13	a	a	DET
fnp-3326	15	14	presynaptic	presynaptic	ADJ
fnp-3326	15	15	protein	protein	NOUN
fnp-3326	15	16	that	that	PRON
fnp-3326	15	17	tends	tend	VERB
fnp-3326	15	18	to	to	PART
fnp-3326	15	19	aggregate	aggregate	VERB
fnp-3326	15	20	and	and	CCONJ
fnp-3326	15	21	become	become	AUX
fnp-3326	15	22	phosphorylated	phosphorylate	VERB
fnp-3326	15	23	at	at	ADP
fnp-3326	15	24	serine	serine	NOUN
fnp-3326	15	25	129	129	NUM
fnp-3326	15	26	under	under	ADP
fnp-3326	15	27	pathological	pathological	ADJ
fnp-3326	15	28	conditions	condition	NOUN
fnp-3326	16	1	[	[	X
fnp-3326	16	2	2	2	NUM
fnp-3326	16	3	]	]	PUNCT
fnp-3326	16	4	.	.	PUNCT
fnp-3326	17	1	rare	rare	ADJ
fnp-3326	17	2	point	point	NOUN
fnp-3326	17	3	mutations	mutation	NOUN
fnp-3326	17	4	in	in	ADP
fnp-3326	17	5	αsyn	αsyn	NOUN
fnp-3326	17	6	and	and	CCONJ
fnp-3326	17	7	gene	gene	NOUN
fnp-3326	17	8	multiplications	multiplication	NOUN
fnp-3326	17	9	also	also	ADV
fnp-3326	17	10	cause	cause	VERB
fnp-3326	17	11	familial	familial	ADJ
fnp-3326	17	12	forms	form	NOUN
fnp-3326	17	13	of	of	ADP
fnp-3326	17	14	pd	pd	NOUN
fnp-3326	17	15	and	and	CCONJ
fnp-3326	17	16	related	relate	VERB
fnp-3326	17	17	neurological	neurological	ADJ
fnp-3326	17	18	conditions	condition	NOUN
fnp-3326	17	19	,	,	PUNCT
fnp-3326	17	20	and	and	CCONJ
fnp-3326	17	21	certain	certain	ADJ
fnp-3326	17	22	single	single	ADJ
fnp-3326	17	23	nucleotide	nucleotide	ADJ
fnp-3326	17	24	polymorphisms	polymorphism	NOUN
fnp-3326	17	25	close	close	ADJ
fnp-3326	17	26	to	to	ADP
fnp-3326	17	27	the	the	DET
fnp-3326	17	28	αsyn	αsyn	ADJ
fnp-3326	17	29	gene	gene	NOUN
fnp-3326	17	30	(	(	PUNCT
fnp-3326	17	31	snca	snca	NOUN
fnp-3326	17	32	)	)	PUNCT
fnp-3326	17	33	locus	locus	NOUN
fnp-3326	17	34	are	be	AUX
fnp-3326	17	35	associated	associate	VERB
fnp-3326	17	36	with	with	ADP
fnp-3326	17	37	increased	increase	VERB
fnp-3326	17	38	risk	risk	NOUN
fnp-3326	17	39	for	for	ADP
fnp-3326	17	40	sporadic	sporadic	ADJ
fnp-3326	17	41	pd	pd	PROPN
fnp-3326	18	1	[	[	X
fnp-3326	18	2	4	4	NUM
fnp-3326	18	3	]	]	PUNCT
fnp-3326	18	4	.	.	PUNCT
fnp-3326	19	1	these	these	DET
fnp-3326	19	2	findings	finding	NOUN
fnp-3326	19	3	make	make	VERB
fnp-3326	19	4	αsyn	αsyn	NOUN
fnp-3326	19	5	a	a	DET
fnp-3326	19	6	focal	focal	ADJ
fnp-3326	19	7	point	point	NOUN
fnp-3326	19	8	of	of	ADP
fnp-3326	19	9	biomarker	biomarker	NOUN
fnp-3326	19	10	and	and	CCONJ
fnp-3326	19	11	drug	drug	NOUN
fnp-3326	19	12	development	development	NOUN
fnp-3326	19	13	programs	program	NOUN
fnp-3326	19	14	for	for	ADP
fnp-3326	19	15	pd	pd	PROPN
fnp-3326	19	16	.	.	PROPN
fnp-3326	20	1	several	several	ADJ
fnp-3326	20	2	years	year	NOUN
fnp-3326	20	3	before	before	ADP
fnp-3326	20	4	the	the	DET
fnp-3326	20	5	first	first	ADJ
fnp-3326	20	6	appearance	appearance	NOUN
fnp-3326	20	7	of	of	ADP
fnp-3326	20	8	motor	motor	NOUN
fnp-3326	20	9	symptoms	symptom	NOUN
fnp-3326	20	10	,	,	PUNCT
fnp-3326	20	11	many	many	ADJ
fnp-3326	20	12	patients	patient	NOUN
fnp-3326	20	13	exhibit	exhibit	VERB
fnp-3326	20	14	a	a	DET
fnp-3326	20	15	variety	variety	NOUN
fnp-3326	20	16	of	of	ADP
fnp-3326	20	17	non	non	ADJ
fnp-3326	20	18	-	-	ADJ
fnp-3326	20	19	motor	motor	ADJ
fnp-3326	20	20	symptoms	symptom	NOUN
fnp-3326	20	21	including	include	VERB
fnp-3326	20	22	constipation	constipation	NOUN
fnp-3326	20	23	,	,	PUNCT
fnp-3326	20	24	sleep	sleep	NOUN
fnp-3326	20	25	disorder	disorder	NOUN
fnp-3326	20	26	,	,	PUNCT
fnp-3326	20	27	depression	depression	NOUN
fnp-3326	20	28	,	,	PUNCT
fnp-3326	20	29	and	and	CCONJ
fnp-3326	20	30	hyposmia	hyposmia	NOUN
fnp-3326	21	1	[	[	X
fnp-3326	21	2	5–7	5–7	X
fnp-3326	21	3	]	]	X
fnp-3326	21	4	.	.	PUNCT
fnp-3326	22	1	indeed	indeed	ADV
fnp-3326	22	2	,	,	PUNCT
fnp-3326	22	3	co	co	NOUN
fnp-3326	22	4	-	-	NOUN
fnp-3326	22	5	occurrence	occurrence	NOUN
fnp-3326	22	6	of	of	ADP
fnp-3326	22	7	some	some	PRON
fnp-3326	22	8	of	of	ADP
fnp-3326	22	9	these	these	DET
fnp-3326	22	10	non	non	ADJ
fnp-3326	22	11	-	-	ADJ
fnp-3326	22	12	motor	motor	ADJ
fnp-3326	22	13	symptoms	symptom	NOUN
fnp-3326	22	14	is	be	AUX
fnp-3326	22	15	coupled	couple	VERB
fnp-3326	22	16	to	to	ADP
fnp-3326	22	17	elevated	elevate	VERB
fnp-3326	22	18	pd	pd	PROPN
fnp-3326	22	19	risk	risk	NOUN
fnp-3326	23	1	[	[	X
fnp-3326	23	2	8–11	8–11	X
fnp-3326	23	3	]	]	PUNCT
fnp-3326	23	4	.	.	PUNCT
fnp-3326	24	1	constipation	constipation	NOUN
fnp-3326	24	2	is	be	AUX
fnp-3326	24	3	an	an	DET
fnp-3326	24	4	important	important	ADJ
fnp-3326	24	5	non	non	ADJ
fnp-3326	24	6	-	-	ADJ
fnp-3326	24	7	motor	motor	ADJ
fnp-3326	24	8	feature	feature	NOUN
fnp-3326	24	9	of	of	ADP
fnp-3326	24	10	prodromal	prodromal	ADJ
fnp-3326	24	11	pd	pd	PROPN
fnp-3326	24	12	,	,	PUNCT
fnp-3326	24	13	with	with	ADP
fnp-3326	24	14	28	28	NUM
fnp-3326	24	15	-	-	SYM
fnp-3326	24	16	61	61	NUM
fnp-3326	24	17	%	%	NOUN
fnp-3326	24	18	of	of	ADP
fnp-3326	24	19	patients	patient	NOUN
fnp-3326	24	20	having	having	AUX
fnp-3326	24	21	exhibited	exhibit	VERB
fnp-3326	24	22	gastrointestinal	gastrointestinal	ADJ
fnp-3326	24	23	dysfunction	dysfunction	NOUN
fnp-3326	24	24	for	for	ADP
fnp-3326	24	25	several	several	ADJ
fnp-3326	24	26	years	year	NOUN
fnp-3326	24	27	during	during	ADP
fnp-3326	24	28	the	the	DET
fnp-3326	24	29	prodrome	prodrome	NOUN
fnp-3326	24	30	[	[	X
fnp-3326	24	31	7,10,12	7,10,12	NUM
fnp-3326	24	32	]	]	PUNCT
fnp-3326	24	33	.	.	PUNCT
fnp-3326	25	1	notably	notably	ADV
fnp-3326	25	2	,	,	PUNCT
fnp-3326	25	3	αsyn	αsyn	NOUN
fnp-3326	25	4	-	-	PUNCT
fnp-3326	25	5	immunoreactive	immunoreactive	ADJ
fnp-3326	25	6	inclusions	inclusion	NOUN
fnp-3326	25	7	have	have	AUX
fnp-3326	25	8	been	be	AUX
fnp-3326	25	9	found	find	VERB
fnp-3326	25	10	in	in	ADP
fnp-3326	25	11	neurons	neuron	NOUN
fnp-3326	25	12	of	of	ADP
fnp-3326	25	13	the	the	DET
fnp-3326	25	14	submucosal	submucosal	NOUN
fnp-3326	25	15	plexus	plexus	NOUN
fnp-3326	25	16	in	in	ADP
fnp-3326	25	17	people	people	NOUN
fnp-3326	25	18	with	with	ADP
fnp-3326	25	19	pd	pd	PROPN
fnp-3326	25	20	[	[	X
fnp-3326	25	21	3,13	3,13	NUM
fnp-3326	25	22	]	]	PUNCT
fnp-3326	25	23	.	.	PUNCT
fnp-3326	26	1	taken	take	VERB
fnp-3326	26	2	together	together	ADV
fnp-3326	26	3	,	,	PUNCT
fnp-3326	26	4	this	this	DET
fnp-3326	26	5	converging	converge	VERB
fnp-3326	26	6	evidence	evidence	NOUN
fnp-3326	26	7	suggests	suggest	VERB
fnp-3326	26	8	an	an	DET
fnp-3326	26	9	early	early	ADJ
fnp-3326	26	10	involvement	involvement	NOUN
fnp-3326	26	11	of	of	ADP
fnp-3326	26	12	the	the	DET
fnp-3326	26	13	enteric	enteric	ADJ
fnp-3326	26	14	nervous	nervous	ADJ
fnp-3326	26	15	system	system	NOUN
fnp-3326	26	16	(	(	PUNCT
fnp-3326	26	17	ens	ens	PROPN
fnp-3326	26	18	)	)	PUNCT
fnp-3326	26	19	in	in	ADP
fnp-3326	26	20	the	the	DET
fnp-3326	26	21	pathogenesis	pathogenesis	NOUN
fnp-3326	26	22	of	of	ADP
fnp-3326	26	23	pd	pd	PROPN
fnp-3326	26	24	.	.	PROPN
fnp-3326	26	25	already	already	ADV
fnp-3326	26	26	over	over	ADP
fnp-3326	26	27	a	a	DET
fnp-3326	26	28	decade	decade	NOUN
fnp-3326	26	29	ago	ago	ADV
fnp-3326	26	30	,	,	PUNCT
fnp-3326	26	31	braak	braak	NOUN
fnp-3326	26	32	and	and	CCONJ
fnp-3326	26	33	colleagues	colleague	NOUN
fnp-3326	26	34	hypothesized	hypothesize	VERB
fnp-3326	26	35	that	that	SCONJ
fnp-3326	26	36	αsyn	αsyn	NOUN
fnp-3326	26	37	-	-	PUNCT
fnp-3326	26	38	immunoreactive	immunoreactive	ADJ
fnp-3326	26	39	inclusions	inclusion	NOUN
fnp-3326	26	40	first	first	ADV
fnp-3326	26	41	appear	appear	VERB
fnp-3326	26	42	in	in	ADP
fnp-3326	26	43	the	the	DET
fnp-3326	26	44	ens	ens	NOUN
fnp-3326	26	45	and	and	CCONJ
fnp-3326	26	46	then	then	ADV
fnp-3326	26	47	occur	occur	VERB
fnp-3326	26	48	in	in	ADP
fnp-3326	26	49	the	the	DET
fnp-3326	26	50	parasympathetic	parasympathetic	NOUN
fnp-3326	26	51	(	(	PUNCT
fnp-3326	26	52	e.g.	e.g.	ADV
fnp-3326	26	53	,	,	PUNCT
fnp-3326	26	54	vagal	vagal	ADJ
fnp-3326	26	55	output	output	NOUN
fnp-3326	26	56	neurons	neuron	NOUN
fnp-3326	26	57	in	in	ADP
fnp-3326	26	58	the	the	DET
fnp-3326	26	59	intestines	intestine	NOUN
fnp-3326	26	60	)	)	PUNCT
fnp-3326	26	61	and	and	CCONJ
fnp-3326	26	62	sympathetic	sympathetic	ADJ
fnp-3326	26	63	(	(	PUNCT
fnp-3326	26	64	e.g.	e.g.	ADV
fnp-3326	26	65	,	,	PUNCT
fnp-3326	26	66	in	in	ADP
fnp-3326	26	67	the	the	DET
fnp-3326	26	68	celiac	celiac	ADJ
fnp-3326	26	69	ganglion	ganglion	NOUN
fnp-3326	26	70	in	in	ADP
fnp-3326	26	71	the	the	DET
fnp-3326	26	72	upper	upper	ADJ
fnp-3326	26	73	abdomen	abdomen	NOUN
fnp-3326	26	74	)	)	PUNCT
fnp-3326	26	75	nervous	nervous	ADJ
fnp-3326	26	76	system	system	NOUN
fnp-3326	26	77	and	and	CCONJ
fnp-3326	26	78	gradually	gradually	ADV
fnp-3326	26	79	engage	engage	VERB
fnp-3326	26	80	the	the	DET
fnp-3326	26	81	brainstem	brainstem	NOUN
fnp-3326	26	82	,	,	PUNCT
fnp-3326	26	83	including	include	VERB
fnp-3326	26	84	the	the	DET
fnp-3326	26	85	vagal	vagal	ADJ
fnp-3326	26	86	dorsal	dorsal	NOUN
fnp-3326	26	87	motor	motor	NOUN
fnp-3326	26	88	nucleus	nucleus	NOUN
fnp-3326	26	89	and	and	CCONJ
fnp-3326	26	90	midbrain	midbrain	NOUN
fnp-3326	26	91	areas	area	NOUN
fnp-3326	26	92	[	[	X
fnp-3326	26	93	3,13	3,13	NUM
fnp-3326	26	94	]	]	PUNCT
fnp-3326	26	95	.	.	PUNCT
fnp-3326	27	1	several	several	ADJ
fnp-3326	27	2	studies	study	NOUN
fnp-3326	27	3	in	in	ADP
fnp-3326	27	4	preclinical	preclinical	ADJ
fnp-3326	27	5	models	model	NOUN
fnp-3326	27	6	have	have	AUX
fnp-3326	27	7	demonstrated	demonstrate	VERB
fnp-3326	27	8	that	that	SCONJ
fnp-3326	27	9	αsyn	αsyn	ADJ
fnp-3326	27	10	pathology	pathology	NOUN
fnp-3326	27	11	in	in	ADP
fnp-3326	27	12	the	the	DET
fnp-3326	27	13	gut	gut	NOUN
fnp-3326	27	14	is	be	AUX
fnp-3326	27	15	associated	associate	VERB
fnp-3326	27	16	with	with	ADP
fnp-3326	27	17	the	the	DET
fnp-3326	27	18	development	development	NOUN
fnp-3326	27	19	of	of	ADP
fnp-3326	27	20	αsyn	αsyn	ADJ
fnp-3326	27	21	pathology	pathology	NOUN
fnp-3326	27	22	in	in	ADP
fnp-3326	27	23	the	the	DET
fnp-3326	27	24	brain	brain	NOUN
fnp-3326	28	1	[	[	X
fnp-3326	28	2	14–21	14–21	NUM
fnp-3326	28	3	]	]	X
fnp-3326	28	4	.	.	PUNCT
fnp-3326	29	1	for	for	ADP
fnp-3326	29	2	a	a	DET
fnp-3326	29	3	better	well	ADJ
fnp-3326	29	4	understanding	understanding	NOUN
fnp-3326	29	5	of	of	ADP
fnp-3326	29	6	pd	pd	NOUN
fnp-3326	29	7	pathogenesis	pathogenesis	NOUN
fnp-3326	29	8	and	and	CCONJ
fnp-3326	29	9	particularly	particularly	ADV
fnp-3326	29	10	events	event	NOUN
fnp-3326	29	11	happening	happen	VERB
fnp-3326	29	12	at	at	ADP
fnp-3326	29	13	preclinical	preclinical	ADJ
fnp-3326	29	14	stages	stage	NOUN
fnp-3326	29	15	of	of	ADP
fnp-3326	29	16	pd	pd	NOUN
fnp-3326	29	17	,	,	PUNCT
fnp-3326	29	18	it	it	PRON
fnp-3326	29	19	is	be	AUX
fnp-3326	29	20	critical	critical	ADJ
fnp-3326	29	21	to	to	PART
fnp-3326	29	22	determine	determine	VERB
fnp-3326	29	23	factors	factor	NOUN
fnp-3326	29	24	that	that	PRON
fnp-3326	29	25	regulate	regulate	VERB
fnp-3326	29	26	αsyn	αsyn	ADJ
fnp-3326	29	27	accumulation	accumulation	NOUN
fnp-3326	29	28	in	in	ADP
fnp-3326	29	29	the	the	DET
fnp-3326	29	30	ens	ens	NOUN
fnp-3326	29	31	and	and	CCONJ
fnp-3326	29	32	to	to	PART
fnp-3326	29	33	understand	understand	VERB
fnp-3326	29	34	whether	whether	SCONJ
fnp-3326	29	35	the	the	DET
fnp-3326	29	36	process	process	NOUN
fnp-3326	29	37	underlying	underlie	VERB
fnp-3326	29	38	αsyn	αsyn	ADJ
fnp-3326	29	39	accumulation	accumulation	NOUN
fnp-3326	29	40	in	in	ADP
fnp-3326	29	41	the	the	DET
fnp-3326	29	42	gut	gut	NOUN
fnp-3326	29	43	can	can	AUX
fnp-3326	29	44	also	also	ADV
fnp-3326	29	45	lead	lead	VERB
fnp-3326	29	46	to	to	ADP
fnp-3326	29	47	αsyn	αsyn	ADJ
fnp-3326	29	48	pathology	pathology	NOUN
fnp-3326	29	49	in	in	ADP
fnp-3326	29	50	the	the	DET
fnp-3326	29	51	brain	brain	NOUN
fnp-3326	29	52	.	.	PUNCT
fnp-3326	30	1	inflammation	inflammation	NOUN
fnp-3326	30	2	can	can	AUX
fnp-3326	30	3	potentially	potentially	ADV
fnp-3326	30	4	trigger	trigger	VERB
fnp-3326	30	5	αsyn	αsyn	ADJ
fnp-3326	30	6	pathology	pathology	NOUN
fnp-3326	30	7	in	in	ADP
fnp-3326	30	8	the	the	DET
fnp-3326	30	9	ens	ens	NOUN
fnp-3326	30	10	of	of	ADP
fnp-3326	30	11	the	the	DET
fnp-3326	30	12	gut	gut	NOUN
fnp-3326	30	13	and	and	CCONJ
fnp-3326	30	14	in	in	ADP
fnp-3326	30	15	the	the	DET
fnp-3326	30	16	brain	brain	NOUN
fnp-3326	30	17	.	.	PUNCT
fnp-3326	31	1	a	a	DET
fnp-3326	31	2	recent	recent	ADJ
fnp-3326	31	3	finding	finding	NOUN
fnp-3326	31	4	in	in	ADP
fnp-3326	31	5	children	child	NOUN
fnp-3326	31	6	with	with	ADP
fnp-3326	31	7	gastrointestinal	gastrointestinal	ADJ
fnp-3326	31	8	inflammation	inflammation	NOUN
fnp-3326	31	9	suggests	suggest	VERB
fnp-3326	31	10	an	an	DET
fnp-3326	31	11	immune	immune	ADJ
fnp-3326	31	12	regulatory	regulatory	ADJ
fnp-3326	31	13	function	function	NOUN
fnp-3326	31	14	of	of	ADP
fnp-3326	31	15	αsyn	αsyn	NOUN
fnp-3326	31	16	[	[	X
fnp-3326	31	17	22	22	NUM
fnp-3326	31	18	]	]	PUNCT
fnp-3326	31	19	.	.	PUNCT
fnp-3326	32	1	immune	immune	ADJ
fnp-3326	32	2	pathways	pathway	NOUN
fnp-3326	32	3	are	be	AUX
fnp-3326	32	4	indeed	indeed	ADV
fnp-3326	32	5	activated	activate	VERB
fnp-3326	32	6	in	in	ADP
fnp-3326	32	7	the	the	DET
fnp-3326	32	8	brain	brain	NOUN
fnp-3326	32	9	and	and	CCONJ
fnp-3326	32	10	colon	colon	NOUN
fnp-3326	32	11	of	of	ADP
fnp-3326	32	12	pd	pd	PROPN
fnp-3326	32	13	cases	case	NOUN
fnp-3326	32	14	[	[	X
fnp-3326	32	15	23,24	23,24	X
fnp-3326	32	16	]	]	PUNCT
fnp-3326	32	17	.	.	PUNCT
fnp-3326	33	1	also	also	ADV
fnp-3326	33	2	,	,	PUNCT
fnp-3326	33	3	several	several	ADJ
fnp-3326	33	4	genes	gene	NOUN
fnp-3326	33	5	associated	associate	VERB
fnp-3326	33	6	with	with	ADP
fnp-3326	33	7	an	an	DET
fnp-3326	33	8	increased	increase	VERB
fnp-3326	33	9	pd	pd	NOUN
fnp-3326	33	10	risk	risk	NOUN
fnp-3326	33	11	have	have	VERB
fnp-3326	33	12	an	an	DET
fnp-3326	33	13	immune	immune	ADJ
fnp-3326	33	14	system	system	NOUN
fnp-3326	33	15	-	-	PUNCT
fnp-3326	33	16	related	relate	VERB
fnp-3326	33	17	function	function	NOUN
fnp-3326	33	18	[	[	X
fnp-3326	33	19	25	25	NUM
fnp-3326	33	20	]	]	PUNCT
fnp-3326	33	21	,	,	PUNCT
fnp-3326	33	22	and	and	CCONJ
fnp-3326	33	23	it	it	PRON
fnp-3326	33	24	was	be	AUX
fnp-3326	33	25	recently	recently	ADV
fnp-3326	33	26	proposed	propose	VERB
fnp-3326	33	27	that	that	SCONJ
fnp-3326	33	28	pd	pd	PROPN
fnp-3326	33	29	heritability	heritability	NOUN
fnp-3326	33	30	is	be	AUX
fnp-3326	33	31	not	not	PART
fnp-3326	33	32	simply	simply	ADV
fnp-3326	33	33	due	due	ADJ
fnp-3326	33	34	to	to	ADP
fnp-3326	33	35	variation	variation	NOUN
fnp-3326	33	36	in	in	ADP
fnp-3326	33	37	brain	brain	NOUN
fnp-3326	33	38	-	-	PUNCT
fnp-3326	33	39	specific	specific	ADJ
fnp-3326	33	40	genes	gene	NOUN
fnp-3326	33	41	,	,	PUNCT
fnp-3326	33	42	but	but	CCONJ
fnp-3326	33	43	that	that	SCONJ
fnp-3326	33	44	several	several	ADJ
fnp-3326	33	45	cell	cell	NOUN
fnp-3326	33	46	types	type	NOUN
fnp-3326	33	47	in	in	ADP
fnp-3326	33	48	different	different	ADJ
fnp-3326	33	49	tissues	tissue	NOUN
fnp-3326	33	50	are	be	AUX
fnp-3326	33	51	involved	involve	VERB
fnp-3326	33	52	[	[	PUNCT
fnp-3326	33	53	26	26	NUM
fnp-3326	33	54	]	]	PUNCT
fnp-3326	33	55	.	.	PUNCT
fnp-3326	34	1	further	further	ADJ
fnp-3326	34	2	genetic	genetic	ADJ
fnp-3326	34	3	evidence	evidence	NOUN
fnp-3326	34	4	supporting	support	VERB
fnp-3326	34	5	a	a	DET
fnp-3326	34	6	role	role	NOUN
fnp-3326	34	7	for	for	ADP
fnp-3326	34	8	immune	immune	ADJ
fnp-3326	34	9	pathways	pathway	NOUN
fnp-3326	34	10	in	in	ADP
fnp-3326	34	11	pd	pd	PROPN
fnp-3326	34	12	pathogenesis	pathogenesis	NOUN
fnp-3326	34	13	is	be	AUX
fnp-3326	34	14	provided	provide	VERB
fnp-3326	34	15	by	by	ADP
fnp-3326	34	16	a	a	DET
fnp-3326	34	17	genome	genome	NOUN
fnp-3326	34	18	-	-	PUNCT
fnp-3326	34	19	wide	wide	ADJ
fnp-3326	34	20	association	association	NOUN
fnp-3326	34	21	study	study	NOUN
fnp-3326	34	22	that	that	PRON
fnp-3326	34	23	identified	identify	VERB
fnp-3326	34	24	common	common	ADJ
fnp-3326	34	25	genetic	genetic	ADJ
fnp-3326	34	26	pathways	pathway	NOUN
fnp-3326	34	27	linking	link	VERB
fnp-3326	34	28	pd	pd	PROPN
fnp-3326	34	29	and	and	CCONJ
fnp-3326	34	30	autoimmune	autoimmune	ADJ
fnp-3326	34	31	disorders	disorder	NOUN
fnp-3326	34	32	[	[	X
fnp-3326	34	33	27	27	NUM
fnp-3326	34	34	]	]	PUNCT
fnp-3326	34	35	.	.	PUNCT
fnp-3326	35	1	most	most	ADV
fnp-3326	35	2	prominently	prominently	ADV
fnp-3326	35	3	,	,	PUNCT
fnp-3326	35	4	lrrk2	lrrk2	PROPN
fnp-3326	35	5	,	,	PUNCT
fnp-3326	35	6	a	a	DET
fnp-3326	35	7	major	major	ADJ
fnp-3326	35	8	genetic	genetic	ADJ
fnp-3326	35	9	risk	risk	NOUN
fnp-3326	35	10	factor	factor	NOUN
fnp-3326	35	11	for	for	ADP
fnp-3326	35	12	pd	pd	PROPN
fnp-3326	36	1	[	[	X
fnp-3326	36	2	28	28	NUM
fnp-3326	36	3	]	]	PUNCT
fnp-3326	36	4	also	also	ADV
fnp-3326	36	5	confers	confer	VERB
fnp-3326	36	6	increased	increase	VERB
fnp-3326	36	7	risk	risk	NOUN
fnp-3326	36	8	for	for	ADP
fnp-3326	36	9	developing	develop	VERB
fnp-3326	36	10	inflammatory	inflammatory	ADJ
fnp-3326	36	11	bowel	bowel	NOUN
fnp-3326	36	12	disease	disease	NOUN
fnp-3326	36	13	(	(	PUNCT
fnp-3326	36	14	ibd	ibd	NOUN
fnp-3326	36	15	)	)	PUNCT
fnp-3326	37	1	[	[	X
fnp-3326	37	2	29	29	NUM
fnp-3326	37	3	]	]	PUNCT
fnp-3326	37	4	.	.	PUNCT
fnp-3326	38	1	certain	certain	ADJ
fnp-3326	38	2	risk	risk	NOUN
fnp-3326	38	3	alleles	allele	NOUN
fnp-3326	38	4	are	be	AUX
fnp-3326	38	5	shared	share	VERB
fnp-3326	38	6	between	between	ADP
fnp-3326	38	7	pd	pd	PROPN
fnp-3326	38	8	and	and	CCONJ
fnp-3326	38	9	crohn	crohn	PROPN
fnp-3326	38	10	’s	’s	PART
fnp-3326	38	11	disease	disease	NOUN
fnp-3326	38	12	[	[	X
fnp-3326	38	13	30	30	NUM
fnp-3326	38	14	]	]	PUNCT
fnp-3326	38	15	,	,	PUNCT
fnp-3326	38	16	and	and	CCONJ
fnp-3326	38	17	lrrk2	lrrk2	NOUN
fnp-3326	38	18	is	be	AUX
fnp-3326	38	19	known	know	VERB
fnp-3326	38	20	to	to	PART
fnp-3326	38	21	modulate	modulate	VERB
fnp-3326	38	22	the	the	DET
fnp-3326	38	23	function	function	NOUN
fnp-3326	38	24	of	of	ADP
fnp-3326	38	25	monocytes	monocyte	NOUN
fnp-3326	38	26	,	,	PUNCT
fnp-3326	38	27	macrophages	macrophage	NOUN
fnp-3326	38	28	and	and	CCONJ
fnp-3326	38	29	other	other	ADJ
fnp-3326	38	30	immune	immune	ADJ
fnp-3326	38	31	cells	cell	NOUN
fnp-3326	39	1	[	[	X
fnp-3326	39	2	31,32	31,32	NUM
fnp-3326	39	3	]	]	PUNCT
fnp-3326	39	4	.	.	PUNCT
fnp-3326	40	1	intriguingly	intriguingly	ADV
fnp-3326	40	2	,	,	PUNCT
fnp-3326	40	3	ibd	ibd	PROPN
fnp-3326	40	4	is	be	AUX
fnp-3326	40	5	associated	associate	VERB
fnp-3326	40	6	with	with	ADP
fnp-3326	40	7	an	an	DET
fnp-3326	40	8	increased	increase	VERB
fnp-3326	40	9	risk	risk	NOUN
fnp-3326	40	10	for	for	ADP
fnp-3326	40	11	developing	develop	VERB
fnp-3326	40	12	pd	pd	NOUN
fnp-3326	40	13	and	and	CCONJ
fnp-3326	40	14	specifically	specifically	ADV
fnp-3326	40	15	blocking	block	VERB
fnp-3326	40	16	the	the	DET
fnp-3326	40	17	tumor	tumor	NOUN
fnp-3326	40	18	necrosis	necrosis	NOUN
fnp-3326	40	19	factor	factor	NOUN
fnp-3326	40	20	(	(	PUNCT
fnp-3326	40	21	tnf	tnf	PROPN
fnp-3326	40	22	)	)	PUNCT
fnp-3326	40	23	pathway	pathway	NOUN
fnp-3326	40	24	reduces	reduce	VERB
fnp-3326	40	25	this	this	DET
fnp-3326	40	26	risk	risk	NOUN
fnp-3326	41	1	[	[	X
fnp-3326	41	2	33–37	33–37	NUM
fnp-3326	41	3	]	]	PUNCT
fnp-3326	41	4	.	.	PUNCT
fnp-3326	42	1	recently	recently	ADV
fnp-3326	42	2	,	,	PUNCT
fnp-3326	42	3	it	it	PRON
fnp-3326	42	4	was	be	AUX
fnp-3326	42	5	reported	report	VERB
fnp-3326	42	6	that	that	SCONJ
fnp-3326	42	7	experimental	experimental	ADJ
fnp-3326	42	8	colitis	colitis	NOUN
fnp-3326	42	9	in	in	ADP
fnp-3326	42	10	αsyn	αsyn	ADJ
fnp-3326	42	11	transgenic	transgenic	NOUN
fnp-3326	42	12	mice	mouse	NOUN
fnp-3326	42	13	leads	lead	VERB
fnp-3326	42	14	to	to	ADP
fnp-3326	42	15	enteric	enteric	ADJ
fnp-3326	42	16	accumulation	accumulation	NOUN
fnp-3326	42	17	of	of	ADP
fnp-3326	42	18	αsyn	αsyn	NOUN
fnp-3326	42	19	and	and	CCONJ
fnp-3326	42	20	the	the	DET
fnp-3326	42	21	development	development	NOUN
fnp-3326	42	22	of	of	ADP
fnp-3326	42	23	pd	pd	ADJ
fnp-3326	42	24	-	-	PUNCT
fnp-3326	42	25	like	like	ADJ
fnp-3326	42	26	brain	brain	NOUN
fnp-3326	42	27	pathology	pathology	NOUN
fnp-3326	42	28	and	and	CCONJ
fnp-3326	42	29	symptoms	symptom	NOUN
fnp-3326	42	30	within	within	ADP
fnp-3326	42	31	a	a	DET
fnp-3326	42	32	few	few	ADJ
fnp-3326	42	33	months	month	NOUN
fnp-3326	43	1	[	[	X
fnp-3326	43	2	38	38	NUM
fnp-3326	43	3	]	]	PUNCT
fnp-3326	43	4	.	.	PUNCT
fnp-3326	44	1	converging	converge	VERB
fnp-3326	44	2	clinical	clinical	ADJ
fnp-3326	44	3	and	and	CCONJ
fnp-3326	44	4	nonclinical	nonclinical	ADJ
fnp-3326	44	5	data	datum	NOUN
fnp-3326	44	6	suggest	suggest	VERB
fnp-3326	44	7	that	that	SCONJ
fnp-3326	44	8	the	the	DET
fnp-3326	44	9	intestinal	intestinal	ADJ
fnp-3326	44	10	immune	immune	ADJ
fnp-3326	44	11	environment	environment	NOUN
fnp-3326	44	12	plays	play	VERB
fnp-3326	44	13	a	a	DET
fnp-3326	44	14	role	role	NOUN
fnp-3326	44	15	in	in	ADP
fnp-3326	44	16	triggering	trigger	VERB
fnp-3326	44	17	pd	pd	PROPN
fnp-3326	44	18	or	or	CCONJ
fnp-3326	44	19	facilitating	facilitate	VERB
fnp-3326	44	20	the	the	DET
fnp-3326	44	21	molecular	molecular	ADJ
fnp-3326	44	22	events	event	NOUN
fnp-3326	44	23	involved	involve	VERB
fnp-3326	44	24	in	in	ADP
fnp-3326	44	25	the	the	DET
fnp-3326	44	26	earliest	early	ADJ
fnp-3326	44	27	phases	phase	NOUN
fnp-3326	44	28	of	of	ADP
fnp-3326	44	29	the	the	DET
fnp-3326	44	30	disease	disease	NOUN
fnp-3326	44	31	process	process	NOUN
fnp-3326	44	32	[	[	X
fnp-3326	44	33	39,40	39,40	NUM
fnp-3326	44	34	]	]	PUNCT
fnp-3326	44	35	.	.	PUNCT
fnp-3326	45	1	here	here	ADV
fnp-3326	45	2	,	,	PUNCT
fnp-3326	45	3	we	we	PRON
fnp-3326	45	4	tested	test	VERB
fnp-3326	45	5	the	the	DET
fnp-3326	45	6	hypothesis	hypothesis	NOUN
fnp-3326	45	7	that	that	DET
fnp-3326	45	8	specific	specific	ADJ
fnp-3326	45	9	types	type	NOUN
fnp-3326	45	10	and	and	CCONJ
fnp-3326	45	11	severity	severity	NOUN
fnp-3326	45	12	of	of	ADP
fnp-3326	45	13	intestinal	intestinal	ADJ
fnp-3326	45	14	inflammation	inflammation	NOUN
fnp-3326	45	15	are	be	AUX
fnp-3326	45	16	required	require	VERB
fnp-3326	45	17	to	to	PART
fnp-3326	45	18	trigger	trigger	VERB
fnp-3326	45	19	the	the	DET
fnp-3326	45	20	accumulation	accumulation	NOUN
fnp-3326	45	21	of	of	ADP
fnp-3326	45	22	αsyn	αsyn	NOUN
fnp-3326	45	23	in	in	ADP
fnp-3326	45	24	the	the	DET
fnp-3326	45	25	ens	ens	NOUN
fnp-3326	45	26	and	and	CCONJ
fnp-3326	45	27	the	the	DET
fnp-3326	45	28	subsequent	subsequent	ADJ
fnp-3326	45	29	development	development	NOUN
fnp-3326	45	30	of	of	ADP
fnp-3326	45	31	αsyn	αsyn	ADJ
fnp-3326	45	32	pathology	pathology	NOUN
fnp-3326	45	33	in	in	ADP
fnp-3326	45	34	the	the	DET
fnp-3326	45	35	brain	brain	NOUN
fnp-3326	45	36	.	.	PUNCT
fnp-3326	46	1	experimental	experimental	ADJ
fnp-3326	46	2	forms	form	NOUN
fnp-3326	46	3	of	of	ADP
fnp-3326	46	4	colitis	colitis	NOUN
fnp-3326	46	5	in	in	ADP
fnp-3326	46	6	wild	wild	ADJ
fnp-3326	46	7	type	type	NOUN
fnp-3326	46	8	and	and	CCONJ
fnp-3326	46	9	αsyn	αsyn	ADJ
fnp-3326	46	10	transgenic	transgenic	NOUN
fnp-3326	46	11	mice	mouse	NOUN
fnp-3326	46	12	demonstrated	demonstrate	VERB
fnp-3326	46	13	that	that	SCONJ
fnp-3326	46	14	the	the	DET
fnp-3326	46	15	type	type	NOUN
fnp-3326	46	16	and	and	CCONJ
fnp-3326	46	17	degree	degree	NOUN
fnp-3326	46	18	of	of	ADP
fnp-3326	46	19	inflammation	inflammation	NOUN
fnp-3326	46	20	regulates	regulate	VERB
fnp-3326	46	21	the	the	DET
fnp-3326	46	22	amount	amount	NOUN
fnp-3326	46	23	of	of	ADP
fnp-3326	46	24	αsyn	αsyn	ADJ
fnp-3326	46	25	accumulation	accumulation	NOUN
fnp-3326	46	26	in	in	ADP
fnp-3326	46	27	the	the	DET
fnp-3326	46	28	colon	colon	NOUN
fnp-3326	46	29	.	.	PUNCT
fnp-3326	47	1	macrophage	macrophage	ADJ
fnp-3326	47	2	-	-	PUNCT
fnp-3326	47	3	related	relate	VERB
fnp-3326	47	4	signaling	signal	VERB
fnp-3326	47	5	limited	limit	VERB
fnp-3326	47	6	the	the	DET
fnp-3326	47	7	extent	extent	NOUN
fnp-3326	47	8	of	of	ADP
fnp-3326	47	9	αsyn	αsyn	PROPN
fnp-3326	47	10	immunoreactivity	immunoreactivity	NOUN
fnp-3326	47	11	as	as	SCONJ
fnp-3326	47	12	demonstrated	demonstrate	VERB
fnp-3326	47	13	in	in	ADP
fnp-3326	47	14	a	a	DET
fnp-3326	47	15	genetic	genetic	ADJ
fnp-3326	47	16	and	and	CCONJ
fnp-3326	47	17	a	a	DET
fnp-3326	47	18	pharmacological	pharmacological	ADJ
fnp-3326	47	19	immune	immune	ADJ
fnp-3326	47	20	modulation	modulation	NOUN
fnp-3326	47	21	paradigm	paradigm	NOUN
fnp-3326	47	22	in	in	ADP
fnp-3326	47	23	the	the	DET
fnp-3326	47	24	experimental	experimental	ADJ
fnp-3326	47	25	colitis	colitis	PROPN
fnp-3326	47	26	mouse	mouse	NOUN
fnp-3326	47	27	model	model	NOUN
fnp-3326	47	28	.	.	PUNCT
fnp-3326	48	1	most	most	ADV
fnp-3326	48	2	remarkable	remarkable	ADJ
fnp-3326	48	3	,	,	PUNCT
fnp-3326	48	4	when	when	SCONJ
fnp-3326	48	5	αsyn	αsyn	ADJ
fnp-3326	48	6	transgenic	transgenic	NOUN
fnp-3326	48	7	mice	mouse	NOUN
fnp-3326	48	8	were	be	AUX
fnp-3326	48	9	exposed	expose	VERB
fnp-3326	48	10	to	to	ADP
fnp-3326	48	11	experimental	experimental	ADJ
fnp-3326	48	12	colitis	colitis	NOUN
fnp-3326	48	13	at	at	ADP
fnp-3326	48	14	3	3	NUM
fnp-3326	48	15	months	month	NOUN
fnp-3326	48	16	of	of	ADP
fnp-3326	48	17	age	age	NOUN
fnp-3326	48	18	and	and	CCONJ
fnp-3326	48	19	then	then	ADV
fnp-3326	48	20	were	be	AUX
fnp-3326	48	21	allowed	allow	VERB
fnp-3326	48	22	to	to	PART
fnp-3326	48	23	age	age	VERB
fnp-3326	48	24	normally	normally	ADV
fnp-3326	48	25	up	up	ADP
fnp-3326	48	26	to	to	ADP
fnp-3326	48	27	9	9	NUM
fnp-3326	48	28	or	or	CCONJ
fnp-3326	48	29	21	21	NUM
fnp-3326	48	30	months	month	NOUN
fnp-3326	48	31	,	,	PUNCT
fnp-3326	48	32	the	the	DET
fnp-3326	48	33	accumulation	accumulation	NOUN
fnp-3326	48	34	of	of	ADP
fnp-3326	48	35	aggregated	aggregate	VERB
fnp-3326	48	36	αsyn	αsyn	NOUN
fnp-3326	48	37	in	in	ADP
fnp-3326	48	38	midbrain	midbrain	NOUN
fnp-3326	48	39	,	,	PUNCT
fnp-3326	48	40	including	include	VERB
fnp-3326	48	41	the	the	DET
fnp-3326	48	42	sn	sn	NOUN
fnp-3326	48	43	,	,	PUNCT
fnp-3326	48	44	was	be	AUX
fnp-3326	48	45	much	much	ADV
fnp-3326	48	46	exacerbated	exacerbate	VERB
fnp-3326	48	47	in	in	ADP
fnp-3326	48	48	the	the	DET
fnp-3326	48	49	21	21	NUM
fnp-3326	48	50	-	-	PUNCT
fnp-3326	48	51	month	month	NOUN
fnp-3326	48	52	-	-	PUNCT
fnp-3326	48	53	old	old	ADJ
fnp-3326	48	54	group	group	NOUN
fnp-3326	48	55	,	,	PUNCT
fnp-3326	48	56	but	but	CCONJ
fnp-3326	48	57	not	not	PART
fnp-3326	48	58	in	in	ADP
fnp-3326	48	59	the	the	DET
fnp-3326	48	60	9	9	NUM
fnp-3326	48	61	-	-	PUNCT
fnp-3326	48	62	month	month	NOUN
fnp-3326	48	63	-	-	PUNCT
fnp-3326	48	64	old	old	ADJ
fnp-3326	48	65	group	group	NOUN
fnp-3326	48	66	.	.	PUNCT
fnp-3326	49	1	these	these	DET
fnp-3326	49	2	21	21	NUM
fnp-3326	49	3	-	-	PUNCT
fnp-3326	49	4	month	month	NOUN
fnp-3326	49	5	-	-	PUNCT
fnp-3326	49	6	old	old	ADJ
fnp-3326	49	7	mice	mouse	NOUN
fnp-3326	49	8	also	also	ADV
fnp-3326	49	9	exhibited	exhibit	VERB
fnp-3326	49	10	loss	loss	NOUN
fnp-3326	49	11	of	of	ADP
fnp-3326	49	12	nigral	nigral	ADJ
fnp-3326	49	13	tyrosine	tyrosine	NOUN
fnp-3326	49	14	hydroxylase	hydroxylase	NOUN
fnp-3326	49	15	-	-	PUNCT
fnp-3326	49	16	immunoreactive	immunoreactive	ADJ
fnp-3326	49	17	neurons	neuron	NOUN
fnp-3326	49	18	.	.	PUNCT
fnp-3326	50	1	together	together	ADV
fnp-3326	50	2	,	,	PUNCT
fnp-3326	50	3	our	our	PRON
fnp-3326	50	4	data	datum	NOUN
fnp-3326	50	5	provide	provide	VERB
fnp-3326	50	6	experimental	experimental	ADJ
fnp-3326	50	7	evidence	evidence	NOUN
fnp-3326	50	8	in	in	ADP
fnp-3326	50	9	mice	mouse	NOUN
fnp-3326	50	10	that	that	SCONJ
fnp-3326	50	11	certain	certain	ADJ
fnp-3326	50	12	specific	specific	ADJ
fnp-3326	50	13	forms	form	NOUN
fnp-3326	50	14	of	of	ADP
fnp-3326	50	15	intestinal	intestinal	ADJ
fnp-3326	50	16	inflammation	inflammation	NOUN
fnp-3326	50	17	might	might	AUX
fnp-3326	50	18	be	be	AUX
fnp-3326	50	19	a	a	DET
fnp-3326	50	20	relevant	relevant	ADJ
fnp-3326	50	21	upstream	upstream	ADJ
fnp-3326	50	22	trigger	trigger	NOUN
fnp-3326	50	23	that	that	PRON
fnp-3326	50	24	plays	play	VERB
fnp-3326	50	25	a	a	DET
fnp-3326	50	26	critical	critical	ADJ
fnp-3326	50	27	role	role	NOUN
fnp-3326	50	28	in	in	ADP
fnp-3326	50	29	the	the	DET
fnp-3326	50	30	initiation	initiation	NOUN
fnp-3326	50	31	of	of	ADP
fnp-3326	50	32	pd	pd	PROPN
fnp-3326	50	33	pathogenesis	pathogenesis	NOUN
fnp-3326	50	34	and	and	CCONJ
fnp-3326	50	35	the	the	DET
fnp-3326	50	36	disease	disease	NOUN
fnp-3326	50	37	progression	progression	NOUN
fnp-3326	50	38	.	.	PUNCT
fnp-3326	51	1	methods	method	NOUN
fnp-3326	51	2	aim	aim	VERB
fnp-3326	51	3	,	,	PUNCT
fnp-3326	51	4	design	design	NOUN
fnp-3326	51	5	and	and	CCONJ
fnp-3326	51	6	setting	set	VERB
fnp-3326	51	7	we	we	PRON
fnp-3326	51	8	aimed	aim	VERB
fnp-3326	51	9	to	to	PART
fnp-3326	51	10	combine	combine	VERB
fnp-3326	51	11	an	an	DET
fnp-3326	51	12	αsyn	αsyn	ADJ
fnp-3326	51	13	transgenic	transgenic	NOUN
fnp-3326	51	14	mouse	mouse	NOUN
fnp-3326	51	15	model	model	NOUN
fnp-3326	51	16	of	of	ADP
fnp-3326	51	17	age	age	NOUN
fnp-3326	51	18	-	-	PUNCT
fnp-3326	51	19	dependent	dependent	ADJ
fnp-3326	51	20	development	development	NOUN
fnp-3326	51	21	of	of	ADP
fnp-3326	51	22	αsyn	αsyn	ADJ
fnp-3326	51	23	pathology	pathology	NOUN
fnp-3326	51	24	with	with	ADP
fnp-3326	51	25	well	well	ADV
fnp-3326	51	26	-	-	PUNCT
fnp-3326	51	27	established	establish	VERB
fnp-3326	51	28	experimental	experimental	ADJ
fnp-3326	51	29	colitis	colitis	NOUN
fnp-3326	51	30	paradigms	paradigm	NOUN
fnp-3326	51	31	in	in	ADP
fnp-3326	51	32	order	order	NOUN
fnp-3326	51	33	to	to	PART
fnp-3326	51	34	explore	explore	VERB
fnp-3326	51	35	the	the	DET
fnp-3326	51	36	effect	effect	NOUN
fnp-3326	51	37	of	of	ADP
fnp-3326	51	38	type	type	NOUN
fnp-3326	51	39	and	and	CCONJ
fnp-3326	51	40	severity	severity	NOUN
fnp-3326	51	41	of	of	ADP
fnp-3326	51	42	immune	immune	ADJ
fnp-3326	51	43	activation	activation	NOUN
fnp-3326	51	44	on	on	ADP
fnp-3326	51	45	the	the	DET
fnp-3326	51	46	development	development	NOUN
fnp-3326	51	47	of	of	ADP
fnp-3326	51	48	αsyn	αsyn	ADJ
fnp-3326	51	49	pathology	pathology	NOUN
fnp-3326	51	50	in	in	ADP
fnp-3326	51	51	the	the	DET
fnp-3326	51	52	colon	colon	NOUN
fnp-3326	51	53	and	and	CCONJ
fnp-3326	51	54	the	the	DET
fnp-3326	51	55	brain	brain	NOUN
fnp-3326	51	56	.	.	PUNCT
fnp-3326	52	1	the	the	DET
fnp-3326	52	2	design	design	NOUN
fnp-3326	52	3	and	and	CCONJ
fnp-3326	52	4	setting	setting	NOUN
fnp-3326	52	5	of	of	ADP
fnp-3326	52	6	the	the	DET
fnp-3326	52	7	different	different	ADJ
fnp-3326	52	8	studies	study	NOUN
fnp-3326	52	9	are	be	AUX
fnp-3326	52	10	illustrated	illustrate	VERB
fnp-3326	52	11	in	in	ADP
fnp-3326	52	12	fig	fig	NOUN
fnp-3326	52	13	.	.	PUNCT
fnp-3326	53	1	1	1	X
fnp-3326	53	2	.	.	X
fnp-3326	53	3	fig	fig	NOUN
fnp-3326	53	4	.	.	PUNCT
fnp-3326	54	1	1	1	NUM
fnp-3326	54	2	age	age	NOUN
fnp-3326	54	3	-	-	PUNCT
fnp-3326	54	4	dependent	dependent	ADJ
fnp-3326	54	5	increase	increase	NOUN
fnp-3326	54	6	of	of	ADP
fnp-3326	54	7	intracellular	intracellular	ADJ
fnp-3326	54	8	αsyn	αsyn	ADJ
fnp-3326	54	9	accumulation	accumulation	NOUN
fnp-3326	54	10	in	in	ADP
fnp-3326	54	11	enteric	enteric	ADJ
fnp-3326	54	12	nervous	nervous	ADJ
fnp-3326	54	13	system	system	NOUN
fnp-3326	54	14	of	of	ADP
fnp-3326	54	15	hemizygous	hemizygous	ADJ
fnp-3326	54	16	(	(	PUNCT
fnp-3326	54	17	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	54	18	transgenic	transgenic	NOUN
fnp-3326	54	19	mice	mouse	NOUN
fnp-3326	54	20	and	and	CCONJ
fnp-3326	54	21	setup	setup	NOUN
fnp-3326	54	22	of	of	ADP
fnp-3326	54	23	the	the	DET
fnp-3326	54	24	experimental	experimental	ADJ
fnp-3326	54	25	colitis	colitis	NOUN
fnp-3326	54	26	paradigms	paradigm	NOUN
fnp-3326	54	27	.	.	PUNCT
fnp-3326	55	1	a	a	DET
fnp-3326	55	2	confocal	confocal	ADJ
fnp-3326	55	3	microscopy	microscopy	NOUN
fnp-3326	55	4	imaging	imaging	NOUN
fnp-3326	55	5	of	of	ADP
fnp-3326	55	6	the	the	DET
fnp-3326	55	7	inclusions	inclusion	NOUN
fnp-3326	55	8	of	of	ADP
fnp-3326	55	9	human	human	ADJ
fnp-3326	55	10	αsyn	αsyn	NOUN
fnp-3326	55	11	(	(	PUNCT
fnp-3326	55	12	red	red	ADJ
fnp-3326	55	13	,	,	PUNCT
fnp-3326	55	14	antibody	antibody	NOUN
fnp-3326	55	15	clone	clone	NOUN
fnp-3326	55	16	211	211	NUM
fnp-3326	55	17	;	;	PUNCT
fnp-3326	55	18	human	human	ADJ
fnp-3326	55	19	αsyn	αsyn	PROPN
fnp-3326	55	20	specific	specific	NOUN
fnp-3326	55	21	)	)	PUNCT
fnp-3326	55	22	within	within	ADP
fnp-3326	55	23	the	the	DET
fnp-3326	55	24	ganglia	ganglia	NOUN
fnp-3326	55	25	of	of	ADP
fnp-3326	55	26	the	the	DET
fnp-3326	55	27	submucosal	submucosal	NOUN
fnp-3326	55	28	plexus	plexus	NOUN
fnp-3326	55	29	(	(	PUNCT
fnp-3326	55	30	green	green	ADJ
fnp-3326	55	31	,	,	PUNCT
fnp-3326	55	32	peripherin	peripherin	NOUN
fnp-3326	55	33	;	;	PUNCT
fnp-3326	55	34	blue	blue	ADJ
fnp-3326	55	35	,	,	PUNCT
fnp-3326	55	36	dapi	dapi	ADJ
fnp-3326	55	37	/	/	SYM
fnp-3326	55	38	nuclei	nucleus	NOUN
fnp-3326	55	39	)	)	PUNCT
fnp-3326	55	40	of	of	ADP
fnp-3326	55	41	hemizygous	hemizygous	ADJ
fnp-3326	55	42	(	(	PUNCT
fnp-3326	55	43	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	55	44	transgenic	transgenic	NOUN
fnp-3326	55	45	mice	mouse	NOUN
fnp-3326	55	46	.	.	PUNCT
fnp-3326	56	1	arrowhead	arrowhead	NOUN
fnp-3326	56	2	points	point	NOUN
fnp-3326	56	3	to	to	ADP
fnp-3326	56	4	one	one	NUM
fnp-3326	56	5	of	of	ADP
fnp-3326	56	6	the	the	DET
fnp-3326	56	7	typical	typical	ADJ
fnp-3326	56	8	irregularly	irregularly	ADV
fnp-3326	56	9	sized	sized	ADJ
fnp-3326	56	10	and	and	CCONJ
fnp-3326	56	11	shaped	shape	VERB
fnp-3326	56	12	αsyn	αsyn	ADJ
fnp-3326	56	13	inclusion	inclusion	NOUN
fnp-3326	56	14	bodies	body	NOUN
fnp-3326	56	15	visualized	visualize	VERB
fnp-3326	56	16	in	in	ADP
fnp-3326	56	17	2d	2d	NUM
fnp-3326	56	18	z	z	NOUN
fnp-3326	56	19	-	-	PUNCT
fnp-3326	56	20	stacks	stack	NOUN
fnp-3326	56	21	of	of	ADP
fnp-3326	56	22	rotated	rotate	VERB
fnp-3326	56	23	confocal	confocal	ADJ
fnp-3326	56	24	images	image	NOUN
fnp-3326	56	25	.	.	PUNCT
fnp-3326	57	1	scale	scale	NOUN
fnp-3326	57	2	bar	bar	NOUN
fnp-3326	57	3	:	:	PUNCT
fnp-3326	57	4	100	100	NUM
fnp-3326	57	5	μm	μm	NOUN
fnp-3326	57	6	.	.	PUNCT
fnp-3326	58	1	b	b	NOUN
fnp-3326	58	2	stereological	stereological	ADJ
fnp-3326	58	3	quantification	quantification	NOUN
fnp-3326	58	4	of	of	ADP
fnp-3326	58	5	normally	normally	ADV
fnp-3326	58	6	occurring	occur	VERB
fnp-3326	58	7	human	human	ADJ
fnp-3326	58	8	αsyn	αsyn	ADJ
fnp-3326	58	9	inclusions	inclusion	NOUN
fnp-3326	58	10	in	in	ADP
fnp-3326	58	11	the	the	DET
fnp-3326	58	12	myenteric	myenteric	ADJ
fnp-3326	58	13	and	and	CCONJ
fnp-3326	58	14	submucosal	submucosal	NOUN
fnp-3326	58	15	plexuses	plexus	NOUN
fnp-3326	58	16	of	of	ADP
fnp-3326	58	17	3and	3and	NUM
fnp-3326	58	18	12	12	NUM
fnp-3326	58	19	-	-	PUNCT
fnp-3326	58	20	month	month	NOUN
fnp-3326	58	21	-	-	PUNCT
fnp-3326	58	22	old	old	ADJ
fnp-3326	58	23	hemizygous	hemizygous	ADJ
fnp-3326	58	24	(	(	PUNCT
fnp-3326	58	25	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	58	26	transgenic	transgenic	NOUN
fnp-3326	58	27	mice	mouse	NOUN
fnp-3326	58	28	(	(	PUNCT
fnp-3326	58	29	n	n	NOUN
fnp-3326	58	30	=	=	SYM
fnp-3326	58	31	4	4	NUM
fnp-3326	58	32	per	per	ADP
fnp-3326	58	33	group	group	NOUN
fnp-3326	58	34	;	;	PUNCT
fnp-3326	58	35	mean	mean	VERB
fnp-3326	58	36	and	and	CCONJ
fnp-3326	58	37	s.e.m	s.e.m	NOUN
fnp-3326	58	38	.	.	PROPN
fnp-3326	58	39	are	be	AUX
fnp-3326	58	40	shown	show	VERB
fnp-3326	58	41	;	;	PUNCT
fnp-3326	58	42	student	student	NOUN
fnp-3326	58	43	t	t	PROPN
fnp-3326	58	44	-	-	PUNCT
fnp-3326	58	45	test	test	NOUN
fnp-3326	58	46	between	between	ADP
fnp-3326	58	47	the	the	DET
fnp-3326	58	48	two	two	NUM
fnp-3326	58	49	age	age	NOUN
fnp-3326	58	50	groups	group	NOUN
fnp-3326	58	51	in	in	ADP
fnp-3326	58	52	each	each	DET
fnp-3326	58	53	region	region	NOUN
fnp-3326	58	54	)	)	PUNCT
fnp-3326	58	55	.	.	PUNCT
fnp-3326	59	1	c	c	NOUN
fnp-3326	59	2	setup	setup	NOUN
fnp-3326	59	3	of	of	ADP
fnp-3326	59	4	experimental	experimental	ADJ
fnp-3326	59	5	colitis	colitis	NOUN
fnp-3326	59	6	paradigms	paradigm	NOUN
fnp-3326	59	7	employing	employ	VERB
fnp-3326	59	8	dextran	dextran	VERB
fnp-3326	59	9	sulfate	sulfate	NOUN
fnp-3326	59	10	sodium	sodium	NOUN
fnp-3326	59	11	(	(	PUNCT
fnp-3326	59	12	dss	dss	NOUN
fnp-3326	59	13	,	,	PUNCT
fnp-3326	59	14	per	per	ADP
fnp-3326	59	15	os	os	NOUN
fnp-3326	59	16	in	in	ADP
fnp-3326	59	17	drinking	drinking	NOUN
fnp-3326	59	18	water	water	NOUN
fnp-3326	59	19	)	)	PUNCT
fnp-3326	59	20	or	or	CCONJ
fnp-3326	59	21	bacterial	bacterial	ADJ
fnp-3326	59	22	lipopolysaccharide	lipopolysaccharide	NOUN
fnp-3326	59	23	(	(	PUNCT
fnp-3326	59	24	lps	lps	PROPN
fnp-3326	59	25	,	,	PUNCT
fnp-3326	59	26	intraperitoneal	intraperitoneal	ADJ
fnp-3326	59	27	injection	injection	NOUN
fnp-3326	59	28	)	)	PUNCT
fnp-3326	59	29	.	.	PUNCT
fnp-3326	60	1	except	except	SCONJ
fnp-3326	60	2	for	for	ADP
fnp-3326	60	3	the	the	DET
fnp-3326	60	4	‘	'	PUNCT
fnp-3326	60	5	chronic	chronic	ADJ
fnp-3326	60	6	dss	dss	NOUN
fnp-3326	60	7	paradigm	paradigm	NOUN
fnp-3326	60	8	,	,	PUNCT
fnp-3326	60	9	constant	constant	ADJ
fnp-3326	60	10	dose	dose	NOUN
fnp-3326	60	11	’	'	PUNCT
fnp-3326	60	12	,	,	PUNCT
fnp-3326	60	13	all	all	DET
fnp-3326	60	14	paradigms	paradigm	NOUN
fnp-3326	60	15	were	be	AUX
fnp-3326	60	16	started	start	VERB
fnp-3326	60	17	at	at	ADP
fnp-3326	60	18	the	the	DET
fnp-3326	60	19	age	age	NOUN
fnp-3326	60	20	of	of	ADP
fnp-3326	60	21	3	3	NUM
fnp-3326	60	22	months	month	NOUN
fnp-3326	60	23	.	.	PUNCT
fnp-3326	61	1	the	the	DET
fnp-3326	61	2	‘	'	PUNCT
fnp-3326	61	3	chronic	chronic	ADJ
fnp-3326	61	4	dss	dss	NOUN
fnp-3326	61	5	paradigm	paradigm	NOUN
fnp-3326	61	6	,	,	PUNCT
fnp-3326	61	7	constant	constant	ADJ
fnp-3326	61	8	dose	dose	NOUN
fnp-3326	61	9	’	'	PUNCT
fnp-3326	61	10	was	be	AUX
fnp-3326	61	11	started	start	VERB
fnp-3326	61	12	in	in	ADP
fnp-3326	61	13	mice	mouse	NOUN
fnp-3326	61	14	aged	age	VERB
fnp-3326	61	15	5	5	NUM
fnp-3326	61	16	months	month	NOUN
fnp-3326	61	17	and	and	CCONJ
fnp-3326	61	18	the	the	DET
fnp-3326	61	19	colon	colon	NOUN
fnp-3326	61	20	were	be	AUX
fnp-3326	61	21	analyzed	analyze	VERB
fnp-3326	61	22	right	right	ADV
fnp-3326	61	23	after	after	ADV
fnp-3326	61	24	.	.	PUNCT
fnp-3326	62	1	for	for	ADP
fnp-3326	62	2	some	some	DET
fnp-3326	62	3	experiments	experiment	NOUN
fnp-3326	62	4	,	,	PUNCT
fnp-3326	62	5	we	we	PRON
fnp-3326	62	6	used	use	VERB
fnp-3326	62	7	a	a	DET
fnp-3326	62	8	‘	'	PUNCT
fnp-3326	62	9	chronic	chronic	ADJ
fnp-3326	62	10	dss	dss	NOUN
fnp-3326	62	11	paradigm	paradigm	NOUN
fnp-3326	62	12	,	,	PUNCT
fnp-3326	62	13	increasing	increase	VERB
fnp-3326	62	14	dose	dose	NOUN
fnp-3326	62	15	’	'	PUNCT
fnp-3326	62	16	,	,	PUNCT
fnp-3326	62	17	to	to	PART
fnp-3326	62	18	mimic	mimic	VERB
fnp-3326	62	19	better	well	ADV
fnp-3326	62	20	the	the	DET
fnp-3326	62	21	chronic	chronic	ADJ
fnp-3326	62	22	nature	nature	NOUN
fnp-3326	62	23	of	of	ADP
fnp-3326	62	24	ibd	ibd	PROPN
fnp-3326	62	25	and	and	CCONJ
fnp-3326	62	26	the	the	DET
fnp-3326	62	27	longer	long	ADJ
fnp-3326	62	28	water	water	NOUN
fnp-3326	62	29	intervals	interval	NOUN
fnp-3326	62	30	are	be	AUX
fnp-3326	62	31	generally	generally	ADV
fnp-3326	62	32	more	more	ADV
fnp-3326	62	33	gentle	gentle	ADJ
fnp-3326	62	34	for	for	ADP
fnp-3326	62	35	the	the	DET
fnp-3326	62	36	mice	mouse	NOUN
fnp-3326	62	37	from	from	ADP
fnp-3326	62	38	an	an	DET
fnp-3326	62	39	animal	animal	NOUN
fnp-3326	62	40	welfare	welfare	NOUN
fnp-3326	62	41	perspective	perspective	NOUN
fnp-3326	62	42	as	as	ADV
fnp-3326	62	43	well	well	ADV
fnp-3326	62	44	.	.	PUNCT
fnp-3326	63	1	under	under	ADP
fnp-3326	63	2	this	this	DET
fnp-3326	63	3	paradigm	paradigm	NOUN
fnp-3326	63	4	,	,	PUNCT
fnp-3326	63	5	we	we	PRON
fnp-3326	63	6	induced	induce	VERB
fnp-3326	63	7	experimental	experimental	ADJ
fnp-3326	63	8	dss	dss	NOUN
fnp-3326	63	9	colitis	colitis	NOUN
fnp-3326	63	10	intermittently	intermittently	ADV
fnp-3326	63	11	as	as	SCONJ
fnp-3326	63	12	indicated	indicate	VERB
fnp-3326	63	13	over	over	ADP
fnp-3326	63	14	23	23	NUM
fnp-3326	63	15	days	day	NOUN
fnp-3326	63	16	,	,	PUNCT
fnp-3326	63	17	then	then	ADV
fnp-3326	63	18	let	let	VERB
fnp-3326	63	19	the	the	DET
fnp-3326	63	20	mice	mice	NOUN
fnp-3326	63	21	recover	recover	VERB
fnp-3326	63	22	and	and	CCONJ
fnp-3326	63	23	age	age	NOUN
fnp-3326	63	24	for	for	ADP
fnp-3326	63	25	two	two	NUM
fnp-3326	63	26	more	more	ADJ
fnp-3326	63	27	months	month	NOUN
fnp-3326	63	28	up	up	ADP
fnp-3326	63	29	to	to	ADP
fnp-3326	63	30	the	the	DET
fnp-3326	63	31	age	age	NOUN
fnp-3326	63	32	of	of	ADP
fnp-3326	63	33	6	6	NUM
fnp-3326	63	34	months	month	NOUN
fnp-3326	63	35	on	on	ADP
fnp-3326	63	36	normal	normal	ADJ
fnp-3326	63	37	drinking	drinking	NOUN
fnp-3326	63	38	water	water	NOUN
fnp-3326	63	39	,	,	PUNCT
fnp-3326	63	40	and	and	CCONJ
fnp-3326	63	41	analyzed	analyze	VERB
fnp-3326	63	42	their	their	PRON
fnp-3326	63	43	colon	colon	NOUN
fnp-3326	63	44	.	.	PUNCT
fnp-3326	64	1	in	in	ADP
fnp-3326	64	2	a	a	DET
fnp-3326	64	3	separate	separate	ADJ
fnp-3326	64	4	experiment	experiment	NOUN
fnp-3326	64	5	,	,	PUNCT
fnp-3326	64	6	we	we	PRON
fnp-3326	64	7	aged	age	VERB
fnp-3326	64	8	the	the	DET
fnp-3326	64	9	mice	mouse	NOUN
fnp-3326	64	10	further	far	ADV
fnp-3326	64	11	up	up	ADP
fnp-3326	64	12	to	to	ADP
fnp-3326	64	13	9	9	NUM
fnp-3326	64	14	or	or	CCONJ
fnp-3326	64	15	21	21	NUM
fnp-3326	64	16	months	month	NOUN
fnp-3326	64	17	and	and	CCONJ
fnp-3326	64	18	analyzed	analyze	VERB
fnp-3326	64	19	their	their	PRON
fnp-3326	64	20	brain	brain	NOUN
fnp-3326	64	21	pathology	pathology	NOUN
fnp-3326	64	22	.	.	PUNCT
fnp-3326	65	1	open	open	VERB
fnp-3326	65	2	arrows	arrow	NOUN
fnp-3326	65	3	on	on	ADP
fnp-3326	65	4	time	time	NOUN
fnp-3326	65	5	axis	axis	NOUN
fnp-3326	65	6	indicate	indicate	VERB
fnp-3326	65	7	that	that	SCONJ
fnp-3326	65	8	colon	colon	NOUN
fnp-3326	65	9	was	be	AUX
fnp-3326	65	10	analyzed	analyze	VERB
fnp-3326	65	11	and	and	CCONJ
fnp-3326	65	12	stars	star	NOUN
fnp-3326	65	13	with	with	ADP
fnp-3326	65	14	closed	closed	ADJ
fnp-3326	65	15	arrows	arrow	NOUN
fnp-3326	65	16	indicate	indicate	VERB
fnp-3326	65	17	that	that	SCONJ
fnp-3326	65	18	brains	brain	NOUN
fnp-3326	65	19	were	be	AUX
fnp-3326	65	20	analyzed	analyze	VERB
fnp-3326	65	21	.	.	PUNCT
fnp-3326	66	1	d	d	X
fnp-3326	66	2	hematoxylin	hematoxylin	NOUN
fnp-3326	66	3	staining	staining	NOUN
fnp-3326	66	4	of	of	ADP
fnp-3326	66	5	35	35	NUM
fnp-3326	66	6	μm	μm	NUM
fnp-3326	66	7	thick	thick	ADJ
fnp-3326	66	8	colon	colon	NOUN
fnp-3326	66	9	sections	section	NOUN
fnp-3326	66	10	of	of	ADP
fnp-3326	66	11	3	3	NUM
fnp-3326	66	12	-	-	PUNCT
fnp-3326	66	13	month	month	NOUN
fnp-3326	66	14	-	-	PUNCT
fnp-3326	66	15	old	old	ADJ
fnp-3326	66	16	hemizygous	hemizygous	ADJ
fnp-3326	66	17	(	(	PUNCT
fnp-3326	66	18	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	66	19	transgenic	transgenic	NOUN
fnp-3326	66	20	mice	mouse	NOUN
fnp-3326	66	21	.	.	PUNCT
fnp-3326	67	1	organizational	organizational	ADJ
fnp-3326	67	2	layers	layer	NOUN
fnp-3326	67	3	of	of	ADP
fnp-3326	67	4	the	the	DET
fnp-3326	67	5	intact	intact	ADJ
fnp-3326	67	6	colon	colon	NOUN
fnp-3326	67	7	(	(	PUNCT
fnp-3326	67	8	left	leave	VERB
fnp-3326	67	9	panel	panel	NOUN
fnp-3326	67	10	)	)	PUNCT
fnp-3326	67	11	.	.	PUNCT
fnp-3326	68	1	representative	representative	ADJ
fnp-3326	68	2	images	image	NOUN
fnp-3326	68	3	of	of	ADP
fnp-3326	68	4	various	various	ADJ
fnp-3326	68	5	severity	severity	NOUN
fnp-3326	68	6	degrees	degree	NOUN
fnp-3326	68	7	of	of	ADP
fnp-3326	68	8	dss	dss	NOUN
fnp-3326	68	9	-	-	PUNCT
fnp-3326	68	10	driven	drive	VERB
fnp-3326	68	11	colitis	colitis	NOUN
fnp-3326	68	12	from	from	ADP
fnp-3326	68	13	weak	weak	ADJ
fnp-3326	68	14	leukocyte	leukocyte	NOUN
fnp-3326	68	15	infiltration	infiltration	NOUN
fnp-3326	68	16	(	(	PUNCT
fnp-3326	68	17	top	top	ADJ
fnp-3326	68	18	panel	panel	NOUN
fnp-3326	68	19	of	of	ADP
fnp-3326	68	20	acute	acute	PROPN
fnp-3326	68	21	dss	dss	NOUN
fnp-3326	68	22	)	)	PUNCT
fnp-3326	68	23	to	to	ADP
fnp-3326	68	24	more	more	ADV
fnp-3326	68	25	extensive	extensive	ADJ
fnp-3326	68	26	leukocyte	leukocyte	NOUN
fnp-3326	68	27	infiltration	infiltration	NOUN
fnp-3326	68	28	with	with	ADP
fnp-3326	68	29	mucosal	mucosal	NOUN
fnp-3326	68	30	ulceration	ulceration	NOUN
fnp-3326	68	31	(	(	PUNCT
fnp-3326	68	32	lowest	low	ADJ
fnp-3326	68	33	panel	panel	NOUN
fnp-3326	68	34	of	of	ADP
fnp-3326	68	35	acute	acute	PROPN
fnp-3326	68	36	dss	dss	NOUN
fnp-3326	68	37	)	)	PUNCT
fnp-3326	68	38	.	.	PUNCT
fnp-3326	69	1	note	note	VERB
fnp-3326	69	2	the	the	DET
fnp-3326	69	3	different	different	ADJ
fnp-3326	69	4	appearance	appearance	NOUN
fnp-3326	69	5	of	of	ADP
fnp-3326	69	6	enteric	enteric	ADJ
fnp-3326	69	7	inflammation	inflammation	NOUN
fnp-3326	69	8	in	in	ADP
fnp-3326	69	9	acute	acute	PROPN
fnp-3326	69	10	lps	lps	PROPN
fnp-3326	69	11	-	-	PUNCT
fnp-3326	69	12	driven	drive	VERB
fnp-3326	69	13	peripheral	peripheral	ADJ
fnp-3326	69	14	inflammation	inflammation	NOUN
fnp-3326	69	15	compared	compare	VERB
fnp-3326	69	16	with	with	ADP
fnp-3326	69	17	dss	dss	NOUN
fnp-3326	69	18	,	,	PUNCT
fnp-3326	69	19	e.g.	e.g.	ADV
fnp-3326	69	20	,	,	PUNCT
fnp-3326	69	21	confined	confine	VERB
fnp-3326	69	22	immune	immune	ADJ
fnp-3326	69	23	cell	cell	NOUN
fnp-3326	69	24	clustering	clustering	NOUN
fnp-3326	69	25	and	and	CCONJ
fnp-3326	69	26	lymphoid	lymphoid	ADJ
fnp-3326	69	27	hyperplasia	hyperplasia	NOUN
fnp-3326	69	28	,	,	PUNCT
fnp-3326	69	29	intact	intact	ADJ
fnp-3326	69	30	mucosal	mucosal	ADJ
fnp-3326	69	31	layer	layer	NOUN
fnp-3326	69	32	.	.	PUNCT
fnp-3326	70	1	scale	scale	NOUN
fnp-3326	70	2	bar	bar	NOUN
fnp-3326	70	3	:	:	PUNCT
fnp-3326	70	4	50	50	NUM
fnp-3326	70	5	μm	μm	NOUN
fnp-3326	70	6	(	(	PUNCT
fnp-3326	70	7	intact	intact	ADJ
fnp-3326	70	8	colon	colon	NOUN
fnp-3326	70	9	)	)	PUNCT
fnp-3326	70	10	,	,	PUNCT
fnp-3326	70	11	100	100	NUM
fnp-3326	70	12	μm	μm	NUM
fnp-3326	70	13	(	(	PUNCT
fnp-3326	70	14	acute	acute	PROPN
fnp-3326	70	15	dss	dss	NOUN
fnp-3326	70	16	)	)	PUNCT
fnp-3326	70	17	,	,	PUNCT
fnp-3326	70	18	and	and	CCONJ
fnp-3326	70	19	200	200	NUM
fnp-3326	70	20	μm	μm	NOUN
fnp-3326	70	21	(	(	PUNCT
fnp-3326	70	22	lps	lps	PROPN
fnp-3326	70	23	)	)	PUNCT
fnp-3326	70	24	.	.	PUNCT
fnp-3326	71	1	mice	mouse	NOUN
fnp-3326	71	2	male	male	ADJ
fnp-3326	71	3	c57bl/6j	c57bl/6j	PROPN
fnp-3326	71	4	wild	wild	ADJ
fnp-3326	71	5	type	type	NOUN
fnp-3326	71	6	mice	mouse	NOUN
fnp-3326	71	7	(	(	PUNCT
fnp-3326	71	8	jackson	jackson	PROPN
fnp-3326	71	9	laboratories	laboratory	NOUN
fnp-3326	71	10	,	,	PUNCT
fnp-3326	71	11	bar	bar	NOUN
fnp-3326	71	12	harbor	harbor	NOUN
fnp-3326	71	13	,	,	PUNCT
fnp-3326	71	14	usa	usa	PROPN
fnp-3326	71	15	)	)	PUNCT
fnp-3326	71	16	,	,	PUNCT
fnp-3326	71	17	hemizygous	hemizygous	ADJ
fnp-3326	71	18	tg(thy1	tg(thy1	NOUN
fnp-3326	71	19	-	-	PUNCT
fnp-3326	71	20	snca*a30p)18pjk	snca*a30p)18pjk	NOUN
fnp-3326	71	21	(	(	PUNCT
fnp-3326	71	22	(	(	PUNCT
fnp-3326	71	23	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	71	24	)	)	PUNCT
fnp-3326	72	1	[	[	X
fnp-3326	72	2	41	41	NUM
fnp-3326	72	3	]	]	PUNCT
fnp-3326	72	4	and	and	CCONJ
fnp-3326	72	5	tg(thy1	tg(thy1	NOUN
fnp-3326	72	6	-	-	PUNCT
fnp-3326	72	7	snca*a30p)18pjk	snca*a30p)18pjk	NOUN
fnp-3326	72	8	crossed	cross	VERB
fnp-3326	72	9	with	with	ADP
fnp-3326	72	10	cx3cr1tm1litt	cx3cr1tm1litt	NOUN
fnp-3326	72	11	(	(	PUNCT
fnp-3326	72	12	(	(	PUNCT
fnp-3326	72	13	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	72	14	/cx3cr1	/cx3cr1	NOUN
fnp-3326	72	15	-	-	PUNCT
fnp-3326	72	16	def	def	ADJ
fnp-3326	72	17	;	;	PUNCT
fnp-3326	72	18	homozygous	homozygous	ADJ
fnp-3326	72	19	for	for	ADP
fnp-3326	72	20	cx3cr1	cx3cr1	PROPN
fnp-3326	72	21	-	-	PUNCT
fnp-3326	72	22	gfp	gfp	NOUN
fnp-3326	72	23	knock	knock	NOUN
fnp-3326	72	24	-	-	PUNCT
fnp-3326	72	25	in	in	ADP
fnp-3326	72	26	allele	allele	NOUN
fnp-3326	72	27	;	;	PUNCT
fnp-3326	72	28	[	[	X
fnp-3326	72	29	42	42	NUM
fnp-3326	72	30	]	]	PUNCT
fnp-3326	72	31	transgenic	transgenic	NOUN
fnp-3326	72	32	mice	mouse	NOUN
fnp-3326	72	33	were	be	AUX
fnp-3326	72	34	used	use	VERB
fnp-3326	72	35	for	for	ADP
fnp-3326	72	36	the	the	DET
fnp-3326	72	37	study	study	NOUN
fnp-3326	72	38	.	.	PUNCT
fnp-3326	73	1	(	(	PUNCT
fnp-3326	73	2	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	73	3	transgenic	transgenic	NOUN
fnp-3326	73	4	mice	mouse	NOUN
fnp-3326	73	5	express	express	VERB
fnp-3326	73	6	mutant	mutant	ADJ
fnp-3326	73	7	human	human	ADJ
fnp-3326	73	8	αsyn	αsyn	NOUN
fnp-3326	73	9	under	under	ADP
fnp-3326	73	10	the	the	DET
fnp-3326	73	11	neuron	neuron	NOUN
fnp-3326	73	12	selective	selective	ADJ
fnp-3326	73	13	thy1	thy1	NOUN
fnp-3326	73	14	promoter	promoter	NOUN
fnp-3326	73	15	.	.	PUNCT
fnp-3326	74	1	(	(	PUNCT
fnp-3326	74	2	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	74	3	transgenic	transgenic	NOUN
fnp-3326	74	4	mice	mouse	NOUN
fnp-3326	74	5	were	be	AUX
fnp-3326	74	6	crossed	cross	VERB
fnp-3326	74	7	to	to	ADP
fnp-3326	74	8	cx3cr1	cx3cr1	VERB
fnp-3326	74	9	-	-	ADJ
fnp-3326	74	10	def	def	ADJ
fnp-3326	74	11	transgenic	transgenic	NOUN
fnp-3326	74	12	mice	mouse	NOUN
fnp-3326	74	13	which	which	PRON
fnp-3326	74	14	express	express	VERB
fnp-3326	74	15	egfp	egfp	NOUN
fnp-3326	74	16	replacing	replace	VERB
fnp-3326	74	17	fractalkine	fractalkine	NOUN
fnp-3326	74	18	receptor	receptor	NOUN
fnp-3326	74	19	gene	gene	NOUN
fnp-3326	74	20	expression	expression	NOUN
fnp-3326	74	21	.	.	PUNCT
fnp-3326	75	1	all	all	DET
fnp-3326	75	2	mice	mouse	NOUN
fnp-3326	75	3	were	be	AUX
fnp-3326	75	4	maintained	maintain	VERB
fnp-3326	75	5	on	on	ADP
fnp-3326	75	6	a	a	DET
fnp-3326	75	7	c57bl/6j	c57bl/6j	NOUN
fnp-3326	75	8	background	background	NOUN
fnp-3326	75	9	for	for	ADP
fnp-3326	75	10	more	more	ADJ
fnp-3326	75	11	than	than	ADP
fnp-3326	75	12	10	10	NUM
fnp-3326	75	13	generations	generation	NOUN
fnp-3326	75	14	and	and	CCONJ
fnp-3326	75	15	under	under	ADP
fnp-3326	75	16	specific	specific	ADJ
fnp-3326	75	17	pathogen	pathogen	NOUN
fnp-3326	75	18	-	-	PUNCT
fnp-3326	75	19	free	free	ADJ
fnp-3326	75	20	conditions	condition	NOUN
fnp-3326	75	21	.	.	PUNCT
fnp-3326	76	1	to	to	ADP
fnp-3326	76	2	the	the	DET
fnp-3326	76	3	extent	extent	NOUN
fnp-3326	76	4	possible	possible	ADJ
fnp-3326	76	5	,	,	PUNCT
fnp-3326	76	6	littermates	littermate	NOUN
fnp-3326	76	7	were	be	AUX
fnp-3326	76	8	used	use	VERB
fnp-3326	76	9	in	in	ADP
fnp-3326	76	10	the	the	DET
fnp-3326	76	11	experiments	experiment	NOUN
fnp-3326	76	12	.	.	PUNCT
fnp-3326	77	1	health	health	NOUN
fnp-3326	77	2	status	status	NOUN
fnp-3326	77	3	was	be	AUX
fnp-3326	77	4	monitored	monitor	VERB
fnp-3326	77	5	daily	daily	ADV
fnp-3326	77	6	during	during	ADP
fnp-3326	77	7	experiments	experiment	NOUN
fnp-3326	77	8	.	.	PUNCT
fnp-3326	78	1	the	the	DET
fnp-3326	78	2	in	in	ADP
fnp-3326	78	3	vivo	vivo	ADJ
fnp-3326	78	4	experiments	experiment	NOUN
fnp-3326	78	5	were	be	AUX
fnp-3326	78	6	endorsed	endorse	VERB
fnp-3326	78	7	by	by	ADP
fnp-3326	78	8	a	a	DET
fnp-3326	78	9	roche	roche	PROPN
fnp-3326	78	10	internal	internal	PROPN
fnp-3326	78	11	review	review	PROPN
fnp-3326	78	12	board	board	NOUN
fnp-3326	78	13	and	and	CCONJ
fnp-3326	78	14	approved	approve	VERB
fnp-3326	78	15	by	by	ADP
fnp-3326	78	16	the	the	DET
fnp-3326	78	17	local	local	ADJ
fnp-3326	78	18	animal	animal	NOUN
fnp-3326	78	19	welfare	welfare	NOUN
fnp-3326	78	20	authorities	authority	NOUN
fnp-3326	78	21	of	of	ADP
fnp-3326	78	22	the	the	DET
fnp-3326	78	23	canton	canton	PROPN
fnp-3326	78	24	basel	basel	PROPN
fnp-3326	78	25	-	-	PUNCT
fnp-3326	78	26	stadt	stadt	NOUN
fnp-3326	78	27	,	,	PUNCT
fnp-3326	78	28	basel	basel	PROPN
fnp-3326	78	29	,	,	PUNCT
fnp-3326	78	30	switzerland	switzerland	PROPN
fnp-3326	78	31	.	.	PUNCT
fnp-3326	79	1	experimental	experimental	ADJ
fnp-3326	79	2	colitis	colitis	NOUN
fnp-3326	79	3	paradigms	paradigm	NOUN
fnp-3326	79	4	in	in	ADP
fnp-3326	79	5	mice	mouse	NOUN
fnp-3326	79	6	paradigms	paradigm	NOUN
fnp-3326	79	7	for	for	ADP
fnp-3326	79	8	the	the	DET
fnp-3326	79	9	induction	induction	NOUN
fnp-3326	79	10	of	of	ADP
fnp-3326	79	11	inflammation	inflammation	NOUN
fnp-3326	79	12	were	be	AUX
fnp-3326	79	13	either	either	CCONJ
fnp-3326	79	14	1	1	NUM
fnp-3326	79	15	week	week	NOUN
fnp-3326	79	16	(	(	PUNCT
fnp-3326	79	17	acute	acute	NOUN
fnp-3326	79	18	)	)	PUNCT
fnp-3326	79	19	or	or	CCONJ
fnp-3326	79	20	3	3	NUM
fnp-3326	79	21	-	-	SYM
fnp-3326	79	22	4	4	NUM
fnp-3326	79	23	weeks	week	NOUN
fnp-3326	79	24	(	(	PUNCT
fnp-3326	79	25	chronic	chronic	NOUN
fnp-3326	79	26	)	)	PUNCT
fnp-3326	79	27	with	with	ADP
fnp-3326	79	28	or	or	CCONJ
fnp-3326	79	29	without	without	ADP
fnp-3326	79	30	an	an	DET
fnp-3326	79	31	incubation	incubation	NOUN
fnp-3326	79	32	phase	phase	NOUN
fnp-3326	79	33	under	under	ADP
fnp-3326	79	34	normal	normal	ADJ
fnp-3326	79	35	conditions	condition	NOUN
fnp-3326	79	36	of	of	ADP
fnp-3326	79	37	2-	2-	NUM
fnp-3326	79	38	,	,	PUNCT
fnp-3326	79	39	6-	6-	NOUN
fnp-3326	79	40	,	,	PUNCT
fnp-3326	79	41	or	or	CCONJ
fnp-3326	79	42	18	18	NUM
fnp-3326	79	43	-	-	PUNCT
fnp-3326	79	44	months	month	NOUN
fnp-3326	79	45	post	post	NOUN
fnp-3326	79	46	application	application	NOUN
fnp-3326	79	47	(	(	PUNCT
fnp-3326	79	48	fig	fig	NOUN
fnp-3326	79	49	.	.	PUNCT
fnp-3326	79	50	1	1	NUM
fnp-3326	79	51	)	)	PUNCT
fnp-3326	79	52	.	.	PUNCT
fnp-3326	80	1	acute	acute	ADJ
fnp-3326	80	2	systemic	systemic	ADJ
fnp-3326	80	3	inflammation	inflammation	NOUN
fnp-3326	80	4	was	be	AUX
fnp-3326	80	5	induced	induce	VERB
fnp-3326	80	6	by	by	ADP
fnp-3326	80	7	intraperitoneal	intraperitoneal	NOUN
fnp-3326	80	8	(	(	PUNCT
fnp-3326	80	9	i.p	i.p	PROPN
fnp-3326	80	10	.	.	PROPN
fnp-3326	80	11	)	)	PUNCT
fnp-3326	81	1	lipopolysaccharide	lipopolysaccharide	ADV
fnp-3326	81	2	(	(	PUNCT
fnp-3326	81	3	lps	lps	PROPN
fnp-3326	81	4	)	)	PUNCT
fnp-3326	81	5	application	application	NOUN
fnp-3326	81	6	[	[	X
fnp-3326	81	7	43	43	NUM
fnp-3326	81	8	]	]	PUNCT
fnp-3326	81	9	of	of	ADP
fnp-3326	81	10	0.5	0.5	NUM
fnp-3326	81	11	mg	mg	PROPN
fnp-3326	81	12	/	/	SYM
fnp-3326	81	13	kg	kg	PROPN
fnp-3326	81	14	in	in	ADP
fnp-3326	81	15	100	100	NUM
fnp-3326	81	16	µl	µl	ADP
fnp-3326	81	17	injection	injection	NOUN
fnp-3326	81	18	volume	volume	NOUN
fnp-3326	81	19	on	on	ADP
fnp-3326	81	20	day	day	NOUN
fnp-3326	81	21	0	0	NUM
fnp-3326	81	22	and	and	CCONJ
fnp-3326	81	23	3	3	NUM
fnp-3326	81	24	(	(	PUNCT
fnp-3326	81	25	sigma	sigma	PROPN
fnp-3326	81	26	-	-	PUNCT
fnp-3326	81	27	aldrich	aldrich	PROPN
fnp-3326	81	28	chemie	chemie	PROPN
fnp-3326	81	29	gmbh	gmbh	PROPN
fnp-3326	81	30	,	,	PUNCT
fnp-3326	81	31	steinheim	steinheim	PROPN
fnp-3326	81	32	,	,	PUNCT
fnp-3326	81	33	germany	germany	PROPN
fnp-3326	81	34	,	,	PUNCT
fnp-3326	81	35	lps	lps	PROPN
fnp-3326	81	36	055	055	NUM
fnp-3326	81	37	:	:	PUNCT
fnp-3326	81	38	b5	b5	PROPN
fnp-3326	81	39	)	)	PUNCT
fnp-3326	81	40	.	.	PUNCT
fnp-3326	82	1	acute	acute	PROPN
fnp-3326	82	2	colitis	colitis	NOUN
fnp-3326	82	3	was	be	AUX
fnp-3326	82	4	induced	induce	VERB
fnp-3326	82	5	by	by	ADP
fnp-3326	82	6	application	application	NOUN
fnp-3326	82	7	of	of	ADP
fnp-3326	82	8	36	36	NUM
fnp-3326	82	9	-	-	PUNCT
fnp-3326	82	10	50kda	50kda	NOUN
fnp-3326	82	11	dextran	dextran	NOUN
fnp-3326	82	12	sulfate	sulfate	NOUN
fnp-3326	82	13	sodium	sodium	NOUN
fnp-3326	82	14	(	(	PUNCT
fnp-3326	82	15	dss	dss	NOUN
fnp-3326	82	16	)	)	PUNCT
fnp-3326	83	1	[	[	X
fnp-3326	83	2	44	44	NUM
fnp-3326	83	3	]	]	PUNCT
fnp-3326	83	4	(	(	PUNCT
fnp-3326	83	5	160110	160110	NUM
fnp-3326	83	6	,	,	PUNCT
fnp-3326	83	7	mp	mp	NOUN
fnp-3326	83	8	biomedicals	biomedical	NOUN
fnp-3326	83	9	,	,	PUNCT
fnp-3326	83	10	llc	llc	PROPN
fnp-3326	83	11	,	,	PUNCT
fnp-3326	83	12	illkirch	illkirch	PROPN
fnp-3326	83	13	,	,	PUNCT
fnp-3326	83	14	france	france	PROPN
fnp-3326	83	15	)	)	PUNCT
fnp-3326	83	16	at	at	ADP
fnp-3326	83	17	1	1	NUM
fnp-3326	83	18	%	%	NOUN
fnp-3326	83	19	,	,	PUNCT
fnp-3326	83	20	2.5	2.5	NUM
fnp-3326	83	21	%	%	NOUN
fnp-3326	83	22	or	or	CCONJ
fnp-3326	83	23	5	5	NUM
fnp-3326	83	24	%	%	NOUN
fnp-3326	83	25	in	in	ADP
fnp-3326	83	26	autoclaved	autoclaved	ADJ
fnp-3326	83	27	drinking	drinking	NOUN
fnp-3326	83	28	water	water	NOUN
fnp-3326	83	29	for	for	ADP
fnp-3326	83	30	5	5	NUM
fnp-3326	83	31	continuous	continuous	ADJ
fnp-3326	83	32	days	day	NOUN
fnp-3326	83	33	respectively	respectively	ADV
fnp-3326	83	34	,	,	PUNCT
fnp-3326	83	35	followed	follow	VERB
fnp-3326	83	36	by	by	ADP
fnp-3326	83	37	2	2	NUM
fnp-3326	83	38	days	day	NOUN
fnp-3326	83	39	of	of	ADP
fnp-3326	83	40	water	water	NOUN
fnp-3326	83	41	(	(	PUNCT
fnp-3326	83	42	1	1	NUM
fnp-3326	83	43	dss	dss	NOUN
fnp-3326	83	44	application	application	NOUN
fnp-3326	83	45	cycle	cycle	NOUN
fnp-3326	83	46	)	)	PUNCT
fnp-3326	83	47	.	.	PUNCT
fnp-3326	84	1	chronic	chronic	ADJ
fnp-3326	84	2	colitis	colitis	NOUN
fnp-3326	84	3	was	be	AUX
fnp-3326	84	4	induced	induce	VERB
fnp-3326	84	5	by	by	ADP
fnp-3326	84	6	two	two	NUM
fnp-3326	84	7	different	different	ADJ
fnp-3326	84	8	dosing	dosing	ADJ
fnp-3326	84	9	protocols	protocol	NOUN
fnp-3326	84	10	:	:	PUNCT
fnp-3326	84	11	i	i	X
fnp-3326	84	12	)	)	PUNCT
fnp-3326	84	13	in	in	ADP
fnp-3326	84	14	a	a	DET
fnp-3326	84	15	constant	constant	ADJ
fnp-3326	84	16	dose	dose	NOUN
fnp-3326	84	17	of	of	ADP
fnp-3326	84	18	dss	dss	NOUN
fnp-3326	84	19	(	(	PUNCT
fnp-3326	84	20	1	1	NUM
fnp-3326	84	21	%	%	NOUN
fnp-3326	84	22	or	or	CCONJ
fnp-3326	84	23	2.5	2.5	NUM
fnp-3326	84	24	%	%	NOUN
fnp-3326	84	25	)	)	PUNCT
fnp-3326	84	26	for	for	ADP
fnp-3326	84	27	5	5	NUM
fnp-3326	84	28	days	day	NOUN
fnp-3326	84	29	and	and	CCONJ
fnp-3326	84	30	changed	change	VERB
fnp-3326	84	31	to	to	ADP
fnp-3326	84	32	2	2	NUM
fnp-3326	84	33	days	day	NOUN
fnp-3326	84	34	with	with	ADP
fnp-3326	84	35	normal	normal	ADJ
fnp-3326	84	36	drinking	drinking	NOUN
fnp-3326	84	37	water	water	NOUN
fnp-3326	84	38	and	and	CCONJ
fnp-3326	84	39	repeated	repeat	VERB
fnp-3326	84	40	three	three	NUM
fnp-3326	84	41	times	time	NOUN
fnp-3326	84	42	(	(	PUNCT
fnp-3326	84	43	4	4	NUM
fnp-3326	84	44	application	application	NOUN
fnp-3326	84	45	cycles	cycle	NOUN
fnp-3326	84	46	in	in	ADP
fnp-3326	84	47	total	total	NOUN
fnp-3326	84	48	)	)	PUNCT
fnp-3326	84	49	;	;	PUNCT
fnp-3326	84	50	ii	ii	X
fnp-3326	84	51	)	)	PUNCT
fnp-3326	84	52	in	in	ADP
fnp-3326	84	53	an	an	DET
fnp-3326	84	54	increasing	increase	VERB
fnp-3326	84	55	dose	dose	NOUN
fnp-3326	84	56	of	of	ADP
fnp-3326	84	57	dss	dss	NOUN
fnp-3326	84	58	starting	start	VERB
fnp-3326	84	59	at	at	ADP
fnp-3326	84	60	1	1	NUM
fnp-3326	84	61	%	%	NOUN
fnp-3326	84	62	for	for	ADP
fnp-3326	84	63	5	5	NUM
fnp-3326	84	64	days	day	NOUN
fnp-3326	84	65	followed	follow	VERB
fnp-3326	84	66	for	for	ADP
fnp-3326	84	67	4	4	NUM
fnp-3326	84	68	days	day	NOUN
fnp-3326	84	69	on	on	ADP
fnp-3326	84	70	normal	normal	ADJ
fnp-3326	84	71	drinking	drinking	NOUN
fnp-3326	84	72	water	water	NOUN
fnp-3326	84	73	,	,	PUNCT
fnp-3326	84	74	then	then	ADV
fnp-3326	84	75	increased	increase	VERB
fnp-3326	84	76	to	to	ADP
fnp-3326	84	77	1.5	1.5	NUM
fnp-3326	84	78	%	%	NOUN
fnp-3326	84	79	dss	dss	NOUN
fnp-3326	84	80	for	for	ADP
fnp-3326	84	81	the	the	DET
fnp-3326	84	82	next	next	ADJ
fnp-3326	84	83	5	5	NUM
fnp-3326	84	84	days	day	NOUN
fnp-3326	84	85	followed	follow	VERB
fnp-3326	84	86	by	by	ADP
fnp-3326	84	87	4	4	NUM
fnp-3326	84	88	days	day	NOUN
fnp-3326	84	89	of	of	ADP
fnp-3326	84	90	water	water	NOUN
fnp-3326	84	91	and	and	CCONJ
fnp-3326	84	92	a	a	DET
fnp-3326	84	93	final	final	ADJ
fnp-3326	84	94	cycle	cycle	NOUN
fnp-3326	84	95	of	of	ADP
fnp-3326	84	96	2	2	NUM
fnp-3326	84	97	%	%	NOUN
fnp-3326	84	98	dss	dss	NOUN
fnp-3326	84	99	followed	follow	VERB
fnp-3326	84	100	by	by	ADP
fnp-3326	84	101	aging	age	VERB
fnp-3326	84	102	the	the	DET
fnp-3326	84	103	mice	mouse	NOUN
fnp-3326	84	104	on	on	ADP
fnp-3326	84	105	normal	normal	ADJ
fnp-3326	84	106	drinking	drinking	NOUN
fnp-3326	84	107	water	water	NOUN
fnp-3326	84	108	until	until	SCONJ
fnp-3326	84	109	they	they	PRON
fnp-3326	84	110	were	be	AUX
fnp-3326	84	111	sacrificed	sacrifice	VERB
fnp-3326	84	112	.	.	PUNCT
fnp-3326	85	1	mice	mouse	NOUN
fnp-3326	85	2	from	from	ADP
fnp-3326	85	3	the	the	DET
fnp-3326	85	4	same	same	ADJ
fnp-3326	85	5	littermate	littermate	NOUN
fnp-3326	85	6	group	group	NOUN
fnp-3326	85	7	were	be	AUX
fnp-3326	85	8	randomized	randomize	VERB
fnp-3326	85	9	per	per	ADP
fnp-3326	85	10	cage	cage	NOUN
fnp-3326	85	11	into	into	ADP
fnp-3326	85	12	‘	'	PUNCT
fnp-3326	85	13	exposed	expose	VERB
fnp-3326	85	14	to	to	ADP
fnp-3326	85	15	inflammation	inflammation	NOUN
fnp-3326	85	16	inducing	induce	VERB
fnp-3326	85	17	agent	agent	NOUN
fnp-3326	85	18	’	'	PUNCT
fnp-3326	85	19	(	(	PUNCT
fnp-3326	85	20	lps	lps	PROPN
fnp-3326	85	21	or	or	CCONJ
fnp-3326	85	22	dss	dss	NOUN
fnp-3326	85	23	,	,	PUNCT
fnp-3326	85	24	respectively	respectively	ADV
fnp-3326	85	25	)	)	PUNCT
fnp-3326	85	26	or	or	CCONJ
fnp-3326	85	27	‘	'	PUNCT
fnp-3326	85	28	unaffected	unaffected	ADJ
fnp-3326	85	29	’	'	PUNCT
fnp-3326	85	30	(	(	PUNCT
fnp-3326	85	31	vehicle	vehicle	NOUN
fnp-3326	85	32	for	for	ADP
fnp-3326	85	33	the	the	DET
fnp-3326	85	34	lps	lps	PROPN
fnp-3326	85	35	paradigm	paradigm	NOUN
fnp-3326	85	36	or	or	CCONJ
fnp-3326	85	37	normal	normal	ADJ
fnp-3326	85	38	drinking	drinking	NOUN
fnp-3326	85	39	water	water	NOUN
fnp-3326	85	40	for	for	ADP
fnp-3326	85	41	the	the	DET
fnp-3326	85	42	dss	dss	NOUN
fnp-3326	85	43	paradigms	paradigm	NOUN
fnp-3326	85	44	,	,	PUNCT
fnp-3326	85	45	respectively	respectively	ADV
fnp-3326	85	46	)	)	PUNCT
fnp-3326	85	47	.	.	PUNCT
fnp-3326	86	1	for	for	ADP
fnp-3326	86	2	the	the	DET
fnp-3326	86	3	long	long	ADJ
fnp-3326	86	4	-	-	PUNCT
fnp-3326	86	5	term	term	NOUN
fnp-3326	86	6	experiments	experiment	NOUN
fnp-3326	86	7	with	with	ADP
fnp-3326	86	8	the	the	DET
fnp-3326	86	9	two	two	NUM
fnp-3326	86	10	aging	age	VERB
fnp-3326	86	11	cohorts	cohort	NOUN
fnp-3326	86	12	‘	'	PUNCT
fnp-3326	86	13	9	9	NUM
fnp-3326	86	14	months	month	NOUN
fnp-3326	86	15	’	'	PUNCT
fnp-3326	86	16	and	and	CCONJ
fnp-3326	86	17	‘	'	PUNCT
fnp-3326	86	18	21	21	NUM
fnp-3326	86	19	months	month	NOUN
fnp-3326	86	20	’	'	PUNCT
fnp-3326	86	21	,	,	PUNCT
fnp-3326	86	22	respectively	respectively	ADV
fnp-3326	86	23	,	,	PUNCT
fnp-3326	86	24	all	all	DET
fnp-3326	86	25	mice	mouse	NOUN
fnp-3326	86	26	in	in	ADP
fnp-3326	86	27	that	that	DET
fnp-3326	86	28	study	study	NOUN
fnp-3326	86	29	were	be	AUX
fnp-3326	86	30	simultaneously	simultaneously	ADV
fnp-3326	86	31	exposed	expose	VERB
fnp-3326	86	32	in	in	ADP
fnp-3326	86	33	one	one	NUM
fnp-3326	86	34	large	large	ADJ
fnp-3326	86	35	cohort	cohort	NOUN
fnp-3326	86	36	at	at	ADP
fnp-3326	86	37	the	the	DET
fnp-3326	86	38	age	age	NOUN
fnp-3326	86	39	of	of	ADP
fnp-3326	86	40	about	about	ADV
fnp-3326	86	41	3	3	NUM
fnp-3326	86	42	months	month	NOUN
fnp-3326	86	43	to	to	ADP
fnp-3326	86	44	the	the	DET
fnp-3326	86	45	increasing	increase	VERB
fnp-3326	86	46	dose	dose	ADJ
fnp-3326	86	47	chronic	chronic	ADJ
fnp-3326	86	48	dss	dss	NOUN
fnp-3326	86	49	paradigm	paradigm	NOUN
fnp-3326	86	50	(	(	PUNCT
fnp-3326	86	51	fig	fig	NOUN
fnp-3326	86	52	.	.	NOUN
fnp-3326	86	53	1	1	NUM
fnp-3326	86	54	)	)	PUNCT
fnp-3326	86	55	and	and	CCONJ
fnp-3326	86	56	dss	dss	NOUN
fnp-3326	86	57	exposure	exposure	NOUN
fnp-3326	86	58	was	be	AUX
fnp-3326	86	59	stopped	stop	VERB
fnp-3326	86	60	for	for	ADP
fnp-3326	86	61	all	all	DET
fnp-3326	86	62	mice	mouse	NOUN
fnp-3326	86	63	on	on	ADP
fnp-3326	86	64	the	the	DET
fnp-3326	86	65	same	same	ADJ
fnp-3326	86	66	day	day	NOUN
fnp-3326	86	67	after	after	ADP
fnp-3326	86	68	the	the	DET
fnp-3326	86	69	23	23	NUM
fnp-3326	86	70	-	-	PUNCT
fnp-3326	86	71	day	day	NOUN
fnp-3326	86	72	period	period	NOUN
fnp-3326	86	73	.	.	PUNCT
fnp-3326	87	1	the	the	DET
fnp-3326	87	2	mice	mouse	NOUN
fnp-3326	87	3	were	be	AUX
fnp-3326	87	4	then	then	ADV
fnp-3326	87	5	kept	keep	VERB
fnp-3326	87	6	and	and	CCONJ
fnp-3326	87	7	aged	aged	ADJ
fnp-3326	87	8	on	on	ADP
fnp-3326	87	9	normal	normal	ADJ
fnp-3326	87	10	drinking	drinking	NOUN
fnp-3326	87	11	water	water	NOUN
fnp-3326	87	12	and	and	CCONJ
fnp-3326	87	13	under	under	ADP
fnp-3326	87	14	normal	normal	ADJ
fnp-3326	87	15	housing	housing	NOUN
fnp-3326	87	16	conditions	condition	NOUN
fnp-3326	87	17	in	in	ADP
fnp-3326	87	18	the	the	DET
fnp-3326	87	19	same	same	ADJ
fnp-3326	87	20	room	room	NOUN
fnp-3326	87	21	until	until	ADP
fnp-3326	87	22	the	the	DET
fnp-3326	87	23	day	day	NOUN
fnp-3326	87	24	they	they	PRON
fnp-3326	87	25	were	be	AUX
fnp-3326	87	26	perfused	perfuse	VERB
fnp-3326	87	27	and	and	CCONJ
fnp-3326	87	28	tissue	tissue	NOUN
fnp-3326	87	29	was	be	AUX
fnp-3326	87	30	collected	collect	VERB
fnp-3326	87	31	.	.	PUNCT
fnp-3326	88	1	il-10	il-10	X
fnp-3326	88	2	treatment	treatment	NOUN
fnp-3326	88	3	and	and	CCONJ
fnp-3326	88	4	exposure	exposure	NOUN
fnp-3326	88	5	measurement	measurement	NOUN
fnp-3326	88	6	two	two	NUM
fnp-3326	88	7	different	different	ADJ
fnp-3326	88	8	forms	form	NOUN
fnp-3326	88	9	of	of	ADP
fnp-3326	88	10	mouse	mouse	NOUN
fnp-3326	88	11	igg	igg	PROPN
fnp-3326	88	12	bound	bind	VERB
fnp-3326	88	13	murine	murine	NOUN
fnp-3326	88	14	il-10	il-10	X
fnp-3326	88	15	(	(	PUNCT
fnp-3326	88	16	migg(v1)-mil10	migg(v1)-mil10	PROPN
fnp-3326	88	17	and	and	CCONJ
fnp-3326	88	18	migg(v2)-mil10	migg(v2)-mil10	NOUN
fnp-3326	88	19	)	)	PUNCT
fnp-3326	88	20	were	be	AUX
fnp-3326	88	21	diluted	dilute	VERB
fnp-3326	88	22	in	in	ADP
fnp-3326	88	23	pre	pre	ADJ
fnp-3326	88	24	-	-	ADJ
fnp-3326	88	25	prepared	prepared	ADJ
fnp-3326	88	26	sterile	sterile	ADJ
fnp-3326	88	27	formulation	formulation	NOUN
fnp-3326	88	28	buffer	buffer	NOUN
fnp-3326	88	29	comprised	comprise	VERB
fnp-3326	88	30	of	of	ADP
fnp-3326	88	31	0.5	0.5	NUM
fnp-3326	88	32	%	%	NOUN
fnp-3326	88	33	mouse	mouse	NOUN
fnp-3326	88	34	serum	serum	NOUN
fnp-3326	88	35	supplemented	supplement	VERB
fnp-3326	88	36	with	with	ADP
fnp-3326	88	37	25	25	NUM
fnp-3326	88	38	mm	mm	NUM
fnp-3326	88	39	citrate	citrate	NOUN
fnp-3326	88	40	,	,	PUNCT
fnp-3326	88	41	300	300	NUM
fnp-3326	88	42	mm	mm	NOUN
fnp-3326	88	43	arginine	arginine	NOUN
fnp-3326	88	44	to	to	ADP
fnp-3326	88	45	a	a	DET
fnp-3326	88	46	final	final	ADJ
fnp-3326	88	47	concentration	concentration	NOUN
fnp-3326	88	48	of	of	ADP
fnp-3326	88	49	0.75	0.75	NUM
fnp-3326	88	50	mg	mg	PROPN
fnp-3326	88	51	/	/	SYM
fnp-3326	88	52	ml	ml	NOUN
fnp-3326	88	53	and	and	CCONJ
fnp-3326	88	54	the	the	DET
fnp-3326	88	55	ph	ph	NOUN
fnp-3326	88	56	adjusted	adjust	VERB
fnp-3326	88	57	to	to	ADP
fnp-3326	88	58	6.7	6.7	NUM
fnp-3326	88	59	on	on	ADP
fnp-3326	88	60	the	the	DET
fnp-3326	88	61	day	day	NOUN
fnp-3326	88	62	of	of	ADP
fnp-3326	88	63	application	application	NOUN
fnp-3326	88	64	.	.	PUNCT
fnp-3326	89	1	each	each	DET
fnp-3326	89	2	mouse	mouse	NOUN
fnp-3326	89	3	was	be	AUX
fnp-3326	89	4	treated	treat	VERB
fnp-3326	89	5	once	once	ADV
fnp-3326	89	6	with	with	ADP
fnp-3326	89	7	150	150	NUM
fnp-3326	89	8	µg	µg	ADV
fnp-3326	89	9	i.p	i.p	PROPN
fnp-3326	89	10	.	.	PUNCT
fnp-3326	90	1	concurrently	concurrently	ADV
fnp-3326	90	2	with	with	ADP
fnp-3326	90	3	the	the	DET
fnp-3326	90	4	initiation	initiation	NOUN
fnp-3326	90	5	of	of	ADP
fnp-3326	90	6	the	the	DET
fnp-3326	90	7	acute	acute	ADJ
fnp-3326	90	8	colitis	colitis	NOUN
fnp-3326	90	9	paradigm	paradigm	NOUN
fnp-3326	90	10	with	with	ADP
fnp-3326	90	11	5	5	NUM
fnp-3326	90	12	%	%	NOUN
fnp-3326	90	13	dss	dss	NOUN
fnp-3326	90	14	.	.	PUNCT
fnp-3326	91	1	the	the	DET
fnp-3326	91	2	concentrations	concentration	NOUN
fnp-3326	91	3	of	of	ADP
fnp-3326	91	4	migg	migg	NOUN
fnp-3326	91	5	-	-	PUNCT
fnp-3326	91	6	mil10	mil10	VERB
fnp-3326	91	7	fusion	fusion	NOUN
fnp-3326	91	8	proteins	protein	NOUN
fnp-3326	91	9	in	in	ADP
fnp-3326	91	10	murine	murine	ADJ
fnp-3326	91	11	serum	serum	NOUN
fnp-3326	91	12	samples	sample	NOUN
fnp-3326	91	13	were	be	AUX
fnp-3326	91	14	determined	determine	VERB
fnp-3326	91	15	by	by	ADP
fnp-3326	91	16	enzyme	enzyme	NOUN
fnp-3326	91	17	-	-	PUNCT
fnp-3326	91	18	linked	link	VERB
fnp-3326	91	19	immunosorbent	immunosorbent	ADJ
fnp-3326	91	20	assays	assay	NOUN
fnp-3326	91	21	(	(	PUNCT
fnp-3326	91	22	elisa	elisa	NOUN
fnp-3326	91	23	)	)	PUNCT
fnp-3326	91	24	specific	specific	NOUN
fnp-3326	91	25	for	for	ADP
fnp-3326	91	26	the	the	DET
fnp-3326	91	27	fab	fab	ADJ
fnp-3326	91	28	moiety	moiety	NOUN
fnp-3326	91	29	of	of	ADP
fnp-3326	91	30	the	the	DET
fnp-3326	91	31	administered	administer	VERB
fnp-3326	91	32	migg	migg	NOUN
fnp-3326	91	33	-	-	PUNCT
fnp-3326	91	34	mil10	mil10	VERB
fnp-3326	91	35	fusion	fusion	NOUN
fnp-3326	91	36	protein	protein	NOUN
fnp-3326	91	37	.	.	PUNCT
fnp-3326	92	1	biotinylated	biotinylate	VERB
fnp-3326	92	2	migg	migg	PROPN
fnp-3326	92	3	-	-	PUNCT
fnp-3326	92	4	mil10	mil10	VERB
fnp-3326	92	5	-	-	PUNCT
fnp-3326	92	6	specific	specific	ADJ
fnp-3326	92	7	target	target	NOUN
fnp-3326	92	8	molecules	molecule	NOUN
fnp-3326	92	9	were	be	AUX
fnp-3326	92	10	used	use	VERB
fnp-3326	92	11	for	for	ADP
fnp-3326	92	12	capturing	capturing	NOUN
fnp-3326	92	13	,	,	PUNCT
fnp-3326	92	14	goat	goat	PROPN
fnp-3326	92	15	anti	anti	ADJ
fnp-3326	92	16	-	-	ADJ
fnp-3326	92	17	mig	mig	ADJ
fnp-3326	92	18	igg	igg	PROPN
fnp-3326	92	19	-	-	PUNCT
fnp-3326	92	20	hrp	hrp	PROPN
fnp-3326	92	21	conjugate	conjugate	ADJ
fnp-3326	92	22	and	and	CCONJ
fnp-3326	92	23	peroxidase	peroxidase	ADJ
fnp-3326	92	24	substrate	substrate	NOUN
fnp-3326	92	25	abts	abt	NOUN
fnp-3326	92	26	were	be	AUX
fnp-3326	92	27	used	use	VERB
fnp-3326	92	28	for	for	ADP
fnp-3326	92	29	quantitative	quantitative	ADJ
fnp-3326	92	30	detection	detection	NOUN
fnp-3326	92	31	of	of	ADP
fnp-3326	92	32	migg	migg	NOUN
fnp-3326	92	33	-	-	PUNCT
fnp-3326	92	34	mil10	mil10	VERB
fnp-3326	92	35	fusion	fusion	NOUN
fnp-3326	92	36	proteins	protein	NOUN
fnp-3326	92	37	.	.	PUNCT
fnp-3326	93	1	immunohistochemistry	immunohistochemistry	NOUN
fnp-3326	93	2	mice	mouse	NOUN
fnp-3326	93	3	were	be	AUX
fnp-3326	93	4	injected	inject	VERB
fnp-3326	93	5	with	with	ADP
fnp-3326	93	6	a	a	DET
fnp-3326	93	7	lethal	lethal	ADJ
fnp-3326	93	8	dose	dose	NOUN
fnp-3326	93	9	of	of	ADP
fnp-3326	93	10	pentobarbital	pentobarbital	NOUN
fnp-3326	93	11	(	(	PUNCT
fnp-3326	93	12	150	150	NUM
fnp-3326	93	13	mg	mg	NUM
fnp-3326	93	14	/	/	SYM
fnp-3326	93	15	kg	kg	NOUN
fnp-3326	93	16	)	)	PUNCT
fnp-3326	93	17	.	.	PUNCT
fnp-3326	94	1	upon	upon	SCONJ
fnp-3326	94	2	full	full	ADJ
fnp-3326	94	3	anesthesia	anesthesia	NOUN
fnp-3326	94	4	,	,	PUNCT
fnp-3326	94	5	mice	mouse	NOUN
fnp-3326	94	6	received	receive	VERB
fnp-3326	94	7	transcardial	transcardial	ADJ
fnp-3326	94	8	perfusion	perfusion	NOUN
fnp-3326	94	9	with	with	ADP
fnp-3326	94	10	room	room	NOUN
fnp-3326	94	11	temperature	temperature	NOUN
fnp-3326	94	12	phosphate	phosphate	NOUN
fnp-3326	94	13	buffered	buffer	VERB
fnp-3326	94	14	saline	saline	NOUN
fnp-3326	94	15	(	(	PUNCT
fnp-3326	94	16	pbs	pbs	PROPN
fnp-3326	94	17	)	)	PUNCT
fnp-3326	94	18	.	.	PUNCT
fnp-3326	95	1	for	for	ADP
fnp-3326	95	2	biochemical	biochemical	ADJ
fnp-3326	95	3	and	and	CCONJ
fnp-3326	95	4	immunohistochemical	immunohistochemical	ADJ
fnp-3326	95	5	analysis	analysis	NOUN
fnp-3326	95	6	,	,	PUNCT
fnp-3326	95	7	one	one	NUM
fnp-3326	95	8	section	section	NOUN
fnp-3326	95	9	of	of	ADP
fnp-3326	95	10	the	the	DET
fnp-3326	95	11	proximal	proximal	ADJ
fnp-3326	95	12	colon	colon	NOUN
fnp-3326	95	13	was	be	AUX
fnp-3326	95	14	either	either	CCONJ
fnp-3326	95	15	fresh	fresh	ADJ
fnp-3326	95	16	frozen	frozen	ADJ
fnp-3326	95	17	and	and	CCONJ
fnp-3326	95	18	stored	store	VERB
fnp-3326	95	19	at	at	ADP
fnp-3326	95	20	-80	-80	NOUN
fnp-3326	95	21	°	°	NOUN
fnp-3326	95	22	c	c	NOUN
fnp-3326	95	23	or	or	CCONJ
fnp-3326	95	24	post	post	VERB
fnp-3326	95	25	-	-	ADJ
fnp-3326	95	26	fixed	fixed	ADJ
fnp-3326	95	27	in	in	ADP
fnp-3326	95	28	4	4	NUM
fnp-3326	95	29	%	%	NOUN
fnp-3326	95	30	paraformaldehyde	paraformaldehyde	NOUN
fnp-3326	95	31	(	(	PUNCT
fnp-3326	95	32	pfa	pfa	NOUN
fnp-3326	95	33	)	)	PUNCT
fnp-3326	95	34	solution	solution	NOUN
fnp-3326	95	35	for	for	ADP
fnp-3326	95	36	24	24	NUM
fnp-3326	95	37	h.	h.	PROPN
fnp-3326	95	38	following	follow	VERB
fnp-3326	95	39	post	post	NOUN
fnp-3326	95	40	-	-	NOUN
fnp-3326	95	41	fixation	fixation	NOUN
fnp-3326	95	42	,	,	PUNCT
fnp-3326	95	43	organs	organ	NOUN
fnp-3326	95	44	were	be	AUX
fnp-3326	95	45	incubated	incubate	VERB
fnp-3326	95	46	in	in	ADP
fnp-3326	95	47	30	30	NUM
fnp-3326	95	48	%	%	NOUN
fnp-3326	95	49	sucrose	sucrose	NOUN
fnp-3326	95	50	/	/	SYM
fnp-3326	95	51	pbs	pbs	PROPN
fnp-3326	95	52	at	at	ADP
fnp-3326	95	53	4	4	NUM
fnp-3326	95	54	°	°	ADP
fnp-3326	95	55	c	c	NOUN
fnp-3326	95	56	for	for	ADP
fnp-3326	95	57	at	at	ADV
fnp-3326	95	58	least	least	ADV
fnp-3326	95	59	48	48	NUM
fnp-3326	95	60	h	h	NOUN
fnp-3326	95	61	before	before	ADP
fnp-3326	95	62	further	further	ADJ
fnp-3326	95	63	processing	processing	NOUN
fnp-3326	95	64	.	.	PUNCT
fnp-3326	96	1	subsequently	subsequently	ADV
fnp-3326	96	2	,	,	PUNCT
fnp-3326	96	3	enteric	enteric	ADJ
fnp-3326	96	4	tissue	tissue	NOUN
fnp-3326	96	5	was	be	AUX
fnp-3326	96	6	cryotome	cryotome	NOUN
fnp-3326	96	7	-	-	PUNCT
fnp-3326	96	8	sectioned	section	VERB
fnp-3326	96	9	to	to	ADP
fnp-3326	96	10	35	35	NUM
fnp-3326	96	11	µm	µm	ADP
fnp-3326	96	12	thick	thick	ADJ
fnp-3326	96	13	longitudinal	longitudinal	ADJ
fnp-3326	96	14	sections	section	NOUN
fnp-3326	96	15	(	(	PUNCT
fnp-3326	96	16	approx	approx	NOUN
fnp-3326	96	17	.	.	PUNCT
fnp-3326	97	1	1	1	NUM
fnp-3326	97	2	cm	cm	NOUN
fnp-3326	97	3	length	length	NOUN
fnp-3326	97	4	)	)	PUNCT
fnp-3326	97	5	.	.	PUNCT
fnp-3326	98	1	the	the	DET
fnp-3326	98	2	brain	brain	NOUN
fnp-3326	98	3	was	be	AUX
fnp-3326	98	4	collected	collect	VERB
fnp-3326	98	5	and	and	CCONJ
fnp-3326	98	6	post	post	ADJ
fnp-3326	98	7	-	-	ADJ
fnp-3326	98	8	fixed	fix	VERB
fnp-3326	98	9	for	for	ADP
fnp-3326	98	10	24	24	NUM
fnp-3326	98	11	h	h	NOUN
fnp-3326	98	12	in	in	ADP
fnp-3326	98	13	4	4	NUM
fnp-3326	98	14	%	%	NOUN
fnp-3326	98	15	pfa	pfa	NOUN
fnp-3326	98	16	followed	follow	VERB
fnp-3326	98	17	by	by	ADP
fnp-3326	98	18	30	30	NUM
fnp-3326	98	19	%	%	NOUN
fnp-3326	98	20	sucrose	sucrose	NOUN
fnp-3326	98	21	in	in	ADP
fnp-3326	98	22	phosphate	phosphate	ADJ
fnp-3326	98	23	buffer	buffer	NOUN
fnp-3326	98	24	until	until	ADP
fnp-3326	98	25	cryo	cryo	NOUN
fnp-3326	98	26	-	-	PUNCT
fnp-3326	98	27	sectioning	sectioning	NOUN
fnp-3326	98	28	of	of	ADP
fnp-3326	98	29	floating	float	VERB
fnp-3326	98	30	sections	section	NOUN
fnp-3326	98	31	at	at	ADP
fnp-3326	98	32	40	40	NUM
fnp-3326	98	33	μm	μm	NOUN
fnp-3326	98	34	.	.	PUNCT
fnp-3326	99	1	histological	histological	ADJ
fnp-3326	99	2	analysis	analysis	NOUN
fnp-3326	99	3	of	of	ADP
fnp-3326	99	4	mouse	mouse	NOUN
fnp-3326	99	5	colon	colon	NOUN
fnp-3326	99	6	was	be	AUX
fnp-3326	99	7	performed	perform	VERB
fnp-3326	99	8	using	use	VERB
fnp-3326	99	9	standard	standard	ADJ
fnp-3326	99	10	hematoxylin	hematoxylin	PROPN
fnp-3326	99	11	staining	staining	NOUN
fnp-3326	99	12	.	.	PUNCT
fnp-3326	100	1	immunohistochemical	immunohistochemical	ADJ
fnp-3326	100	2	staining	staining	NOUN
fnp-3326	100	3	was	be	AUX
fnp-3326	100	4	accomplished	accomplish	VERB
fnp-3326	100	5	using	use	VERB
fnp-3326	100	6	the	the	DET
fnp-3326	100	7	vectastain	vectastain	NOUN
fnp-3326	100	8	elite	elite	ADJ
fnp-3326	100	9	abc	abc	PROPN
fnp-3326	100	10	kits	kits	PROPN
fnp-3326	100	11	and	and	CCONJ
fnp-3326	100	12	peroxidase	peroxidase	NOUN
fnp-3326	100	13	substrate	substrate	NOUN
fnp-3326	100	14	kit	kit	NOUN
fnp-3326	100	15	sk-4100	sk-4100	NOUN
fnp-3326	100	16	(	(	PUNCT
fnp-3326	100	17	vector	vector	NOUN
fnp-3326	100	18	laboratories	laboratory	NOUN
fnp-3326	100	19	,	,	PUNCT
fnp-3326	100	20	burlingame	burlingame	PROPN
fnp-3326	100	21	,	,	PUNCT
fnp-3326	100	22	ca	ca	PROPN
fnp-3326	100	23	,	,	PUNCT
fnp-3326	100	24	usa	usa	PROPN
fnp-3326	100	25	)	)	PUNCT
fnp-3326	100	26	or	or	CCONJ
fnp-3326	100	27	fluorescently	fluorescently	ADV
fnp-3326	100	28	labelled	label	VERB
fnp-3326	100	29	secondary	secondary	ADJ
fnp-3326	100	30	antibodies	antibody	NOUN
fnp-3326	100	31	(	(	PUNCT
fnp-3326	100	32	alexa	alexa	PROPN
fnp-3326	100	33	488	488	NUM
fnp-3326	100	34	,	,	PUNCT
fnp-3326	100	35	555	555	NUM
fnp-3326	100	36	or	or	CCONJ
fnp-3326	100	37	647	647	NUM
fnp-3326	100	38	,	,	PUNCT
fnp-3326	100	39	life	life	NOUN
fnp-3326	100	40	technologies	technology	NOUN
fnp-3326	100	41	,	,	PUNCT
fnp-3326	100	42	zug	zug	PROPN
fnp-3326	100	43	,	,	PUNCT
fnp-3326	100	44	switzerland	switzerland	PROPN
fnp-3326	100	45	)	)	PUNCT
fnp-3326	100	46	.	.	PUNCT
fnp-3326	101	1	the	the	DET
fnp-3326	101	2	following	following	ADJ
fnp-3326	101	3	primary	primary	ADJ
fnp-3326	101	4	antibodies	antibody	NOUN
fnp-3326	101	5	have	have	AUX
fnp-3326	101	6	been	be	AUX
fnp-3326	101	7	used	use	VERB
fnp-3326	101	8	for	for	ADP
fnp-3326	101	9	overnight	overnight	ADJ
fnp-3326	101	10	incubation	incubation	NOUN
fnp-3326	101	11	at	at	ADP
fnp-3326	101	12	a	a	DET
fnp-3326	101	13	dilution	dilution	NOUN
fnp-3326	101	14	of	of	ADP
fnp-3326	101	15	1:1000	1:1000	NUM
fnp-3326	101	16	;	;	PUNCT
fnp-3326	101	17	monoclonal	monoclonal	NOUN
fnp-3326	101	18	antibody	antibody	NOUN
fnp-3326	101	19	to	to	ADP
fnp-3326	101	20	human	human	ADJ
fnp-3326	101	21	αsyn	αsyn	NOUN
fnp-3326	101	22	(	(	PUNCT
fnp-3326	101	23	clone	clone	NOUN
fnp-3326	101	24	211	211	NUM
fnp-3326	101	25	,	,	PUNCT
fnp-3326	101	26	sc-12767	sc-12767	NOUN
fnp-3326	101	27	,	,	PUNCT
fnp-3326	101	28	santa	santa	PROPN
fnp-3326	101	29	cruz	cruz	PROPN
fnp-3326	101	30	biotechnology	biotechnology	PROPN
fnp-3326	101	31	,	,	PUNCT
fnp-3326	101	32	heidelberg	heidelberg	PROPN
fnp-3326	101	33	,	,	PUNCT
fnp-3326	101	34	germany	germany	PROPN
fnp-3326	101	35	;	;	PUNCT
fnp-3326	101	36	specific	specific	ADJ
fnp-3326	101	37	to	to	ADP
fnp-3326	101	38	human	human	ADJ
fnp-3326	101	39	αsyn	αsyn	NOUN
fnp-3326	101	40	and	and	CCONJ
fnp-3326	101	41	binds	bind	VERB
fnp-3326	101	42	to	to	ADP
fnp-3326	101	43	normal	normal	ADJ
fnp-3326	101	44	αsyn	αsyn	NOUN
fnp-3326	101	45	as	as	ADV
fnp-3326	101	46	well	well	ADV
fnp-3326	101	47	as	as	ADP
fnp-3326	101	48	abnormal	abnormal	ADJ
fnp-3326	101	49	αsyn	αsyn	ADJ
fnp-3326	101	50	inclusions	inclusion	NOUN
fnp-3326	101	51	which	which	PRON
fnp-3326	101	52	contain	contain	VERB
fnp-3326	101	53	the	the	DET
fnp-3326	101	54	respective	respective	ADJ
fnp-3326	101	55	epitope	epitope	NOUN
fnp-3326	101	56	)	)	PUNCT
fnp-3326	101	57	,	,	PUNCT
fnp-3326	101	58	monoclonal	monoclonal	NOUN
fnp-3326	101	59	antibody	antibody	NOUN
fnp-3326	101	60	generated	generate	VERB
fnp-3326	101	61	towards	towards	ADP
fnp-3326	101	62	rat	rat	NOUN
fnp-3326	101	63	αsyn	αsyn	PROPN
fnp-3326	101	64	,	,	PUNCT
fnp-3326	101	65	cross	cross	ADJ
fnp-3326	101	66	-	-	ADJ
fnp-3326	101	67	reactive	reactive	ADJ
fnp-3326	101	68	with	with	ADP
fnp-3326	101	69	murine	murine	ADJ
fnp-3326	101	70	and	and	CCONJ
fnp-3326	101	71	human	human	ADJ
fnp-3326	101	72	αsyn	αsyn	NOUN
fnp-3326	101	73	(	(	PUNCT
fnp-3326	101	74	syn1	syn1	NOUN
fnp-3326	101	75	/	/	SYM
fnp-3326	101	76	clone	clone	NOUN
fnp-3326	101	77	42	42	NUM
fnp-3326	101	78	,	,	PUNCT
fnp-3326	101	79	bd	bd	PROPN
fnp-3326	101	80	transduction	transduction	NOUN
fnp-3326	101	81	laboratories	laboratory	NOUN
fnp-3326	101	82	,	,	PUNCT
fnp-3326	101	83	allschwil	allschwil	PROPN
fnp-3326	101	84	,	,	PUNCT
fnp-3326	101	85	switzerland	switzerland	PROPN
fnp-3326	101	86	;	;	PUNCT
fnp-3326	101	87	used	use	VERB
fnp-3326	101	88	for	for	ADP
fnp-3326	101	89	wild	wild	ADJ
fnp-3326	101	90	type	type	NOUN
fnp-3326	101	91	mice	mouse	NOUN
fnp-3326	101	92	)	)	PUNCT
fnp-3326	101	93	,	,	PUNCT
fnp-3326	101	94	polyclonal	polyclonal	ADJ
fnp-3326	101	95	antibody	antibody	NOUN
fnp-3326	101	96	to	to	ADP
fnp-3326	101	97	the	the	DET
fnp-3326	101	98	peripheral	peripheral	ADJ
fnp-3326	101	99	neuronal	neuronal	ADJ
fnp-3326	101	100	marker	marker	NOUN
fnp-3326	101	101	peripherin	peripherin	NOUN
fnp-3326	101	102	(	(	PUNCT
fnp-3326	101	103	millipore	millipore	PROPN
fnp-3326	101	104	corporation	corporation	PROPN
fnp-3326	101	105	,	,	PUNCT
fnp-3326	101	106	billerica	billerica	PROPN
fnp-3326	101	107	,	,	PUNCT
fnp-3326	101	108	ma	ma	PROPN
fnp-3326	101	109	,	,	PUNCT
fnp-3326	101	110	usa	usa	PROPN
fnp-3326	101	111	)	)	PUNCT
fnp-3326	101	112	,	,	PUNCT
fnp-3326	101	113	and	and	CCONJ
fnp-3326	101	114	polyclonal	polyclonal	ADJ
fnp-3326	101	115	antibody	antibody	NOUN
fnp-3326	101	116	to	to	ADP
fnp-3326	101	117	macrophage	macrophage	ADJ
fnp-3326	101	118	marker	marker	NOUN
fnp-3326	101	119	iba-1	iba-1	PUNCT
fnp-3326	101	120	(	(	PUNCT
fnp-3326	101	121	wako	wako	PROPN
fnp-3326	101	122	chemical	chemical	PROPN
fnp-3326	101	123	gmbh	gmbh	PROPN
fnp-3326	101	124	,	,	PUNCT
fnp-3326	101	125	neuss	neuss	PROPN
fnp-3326	101	126	,	,	PUNCT
fnp-3326	101	127	germany	germany	PROPN
fnp-3326	101	128	)	)	PUNCT
fnp-3326	101	129	.	.	PUNCT
fnp-3326	102	1	to	to	PART
fnp-3326	102	2	detect	detect	VERB
fnp-3326	102	3	αsyn	αsyn	NOUN
fnp-3326	102	4	phosphorylated	phosphorylate	VERB
fnp-3326	102	5	at	at	ADP
fnp-3326	102	6	serine	serine	NOUN
fnp-3326	102	7	129	129	NUM
fnp-3326	102	8	(	(	PUNCT
fnp-3326	102	9	pser129	pser129	ADJ
fnp-3326	102	10	-	-	ADJ
fnp-3326	102	11	positive	positive	ADJ
fnp-3326	102	12	inclusions	inclusion	NOUN
fnp-3326	102	13	of	of	ADP
fnp-3326	102	14	pathological	pathological	ADJ
fnp-3326	102	15	/	/	SYM
fnp-3326	102	16	abnormal	abnormal	ADJ
fnp-3326	102	17	αsyn	αsyn	NOUN
fnp-3326	102	18	)	)	PUNCT
fnp-3326	102	19	in	in	ADP
fnp-3326	102	20	the	the	DET
fnp-3326	102	21	free	free	ADV
fnp-3326	102	22	-	-	PUNCT
fnp-3326	102	23	floating	float	VERB
fnp-3326	102	24	brain	brain	NOUN
fnp-3326	102	25	sections	section	NOUN
fnp-3326	102	26	,	,	PUNCT
fnp-3326	102	27	monoclonal	monoclonal	NOUN
fnp-3326	102	28	antibody	antibody	NOUN
fnp-3326	102	29	(	(	PUNCT
fnp-3326	102	30	ab51253	ab51253	ADJ
fnp-3326	102	31	,	,	PUNCT
fnp-3326	102	32	abcam	abcam	PROPN
fnp-3326	102	33	,	,	PUNCT
fnp-3326	102	34	cambridge	cambridge	PROPN
fnp-3326	102	35	,	,	PUNCT
fnp-3326	102	36	usa	usa	PROPN
fnp-3326	102	37	)	)	PUNCT
fnp-3326	102	38	was	be	AUX
fnp-3326	102	39	used	use	VERB
fnp-3326	102	40	at	at	ADP
fnp-3326	102	41	a	a	DET
fnp-3326	102	42	dilution	dilution	NOUN
fnp-3326	102	43	of	of	ADP
fnp-3326	102	44	1:10000	1:10000	NUM
fnp-3326	102	45	.	.	PUNCT
fnp-3326	103	1	prior	prior	ADV
fnp-3326	103	2	to	to	ADP
fnp-3326	103	3	the	the	DET
fnp-3326	103	4	pser129	pser129	PROPN
fnp-3326	103	5	staining	stain	VERB
fnp-3326	103	6	,	,	PUNCT
fnp-3326	103	7	the	the	DET
fnp-3326	103	8	free	free	ADV
fnp-3326	103	9	-	-	PUNCT
fnp-3326	103	10	floating	float	VERB
fnp-3326	103	11	brain	brain	NOUN
fnp-3326	103	12	sections	section	NOUN
fnp-3326	103	13	were	be	AUX
fnp-3326	103	14	incubated	incubate	VERB
fnp-3326	103	15	for	for	ADP
fnp-3326	103	16	10	10	NUM
fnp-3326	103	17	min	min	NOUN
fnp-3326	103	18	at	at	ADP
fnp-3326	103	19	room	room	NOUN
fnp-3326	103	20	temperature	temperature	NOUN
fnp-3326	103	21	in	in	ADP
fnp-3326	103	22	a	a	DET
fnp-3326	103	23	phosphate	phosphate	ADJ
fnp-3326	103	24	buffered	buffer	VERB
fnp-3326	103	25	saline	saline	NOUN
fnp-3326	103	26	solution	solution	NOUN
fnp-3326	103	27	containing	contain	VERB
fnp-3326	103	28	10	10	NUM
fnp-3326	103	29	μg	μg	NOUN
fnp-3326	103	30	/	/	SYM
fnp-3326	103	31	ml	ml	NOUN
fnp-3326	103	32	proteinase	proteinase	NOUN
fnp-3326	103	33	k	k	PROPN
fnp-3326	103	34	(	(	PUNCT
fnp-3326	103	35	cat	cat	NOUN
fnp-3326	103	36	#	#	NOUN
fnp-3326	103	37	25530015	25530015	NUM
fnp-3326	103	38	;	;	PUNCT
fnp-3326	103	39	invitrogen	invitrogen	PROPN
fnp-3326	103	40	,	,	PUNCT
fnp-3326	103	41	california	california	PROPN
fnp-3326	103	42	,	,	PUNCT
fnp-3326	103	43	usa	usa	PROPN
fnp-3326	103	44	)	)	PUNCT
fnp-3326	103	45	.	.	PUNCT
fnp-3326	104	1	tyrosine	tyrosine	NOUN
fnp-3326	104	2	hydroxylase	hydroxylase	NOUN
fnp-3326	104	3	(	(	PUNCT
fnp-3326	104	4	th)-immunoreactive	th)-immunoreactive	ADJ
fnp-3326	104	5	cells	cell	NOUN
fnp-3326	104	6	were	be	AUX
fnp-3326	104	7	detected	detect	VERB
fnp-3326	104	8	using	use	VERB
fnp-3326	104	9	a	a	DET
fnp-3326	104	10	polyclonal	polyclonal	ADJ
fnp-3326	104	11	antibody	antibody	NOUN
fnp-3326	104	12	(	(	PUNCT
fnp-3326	104	13	657012	657012	NUM
fnp-3326	104	14	,	,	PUNCT
fnp-3326	104	15	millipore	millipore	PROPN
fnp-3326	104	16	sigma	sigma	PROPN
fnp-3326	104	17	)	)	PUNCT
fnp-3326	104	18	at	at	ADP
fnp-3326	104	19	a	a	DET
fnp-3326	104	20	dilution	dilution	NOUN
fnp-3326	104	21	of	of	ADP
fnp-3326	104	22	1:1000	1:1000	NUM
fnp-3326	104	23	.	.	PUNCT
fnp-3326	105	1	to	to	PART
fnp-3326	105	2	measure	measure	VERB
fnp-3326	105	3	the	the	DET
fnp-3326	105	4	density	density	NOUN
fnp-3326	105	5	of	of	ADP
fnp-3326	105	6	nissl	nissl	ADJ
fnp-3326	105	7	-	-	PUNCT
fnp-3326	105	8	positive	positive	ADJ
fnp-3326	105	9	cells	cell	NOUN
fnp-3326	105	10	,	,	PUNCT
fnp-3326	105	11	the	the	DET
fnp-3326	105	12	th	th	ADV
fnp-3326	105	13	-	-	PUNCT
fnp-3326	105	14	stained	stain	VERB
fnp-3326	105	15	cells	cell	NOUN
fnp-3326	105	16	were	be	AUX
fnp-3326	105	17	counter	counter	ADJ
fnp-3326	105	18	-	-	VERB
fnp-3326	105	19	stained	stain	VERB
fnp-3326	105	20	with	with	ADP
fnp-3326	105	21	cresyl	cresyl	ADJ
fnp-3326	105	22	violet	violet	NOUN
fnp-3326	105	23	.	.	PUNCT
fnp-3326	106	1	the	the	DET
fnp-3326	106	2	slides	slide	NOUN
fnp-3326	106	3	were	be	AUX
fnp-3326	106	4	incubated	incubate	VERB
fnp-3326	106	5	in	in	ADP
fnp-3326	106	6	0.1	0.1	NUM
fnp-3326	106	7	%	%	NOUN
fnp-3326	106	8	cresyl	cresyl	ADJ
fnp-3326	106	9	violet	violet	NOUN
fnp-3326	106	10	solution	solution	NOUN
fnp-3326	106	11	for	for	ADP
fnp-3326	106	12	9	9	NUM
fnp-3326	106	13	min	min	NOUN
fnp-3326	106	14	and	and	CCONJ
fnp-3326	106	15	then	then	ADV
fnp-3326	106	16	dehydrated	dehydrate	VERB
fnp-3326	106	17	in	in	ADP
fnp-3326	106	18	95	95	NUM
fnp-3326	106	19	%	%	NOUN
fnp-3326	106	20	and	and	CCONJ
fnp-3326	106	21	100	100	NUM
fnp-3326	106	22	%	%	NOUN
fnp-3326	106	23	ethanol	ethanol	NOUN
fnp-3326	106	24	and	and	CCONJ
fnp-3326	106	25	then	then	ADV
fnp-3326	106	26	xylene	xylene	NOUN
fnp-3326	106	27	prior	prior	ADV
fnp-3326	106	28	to	to	PART
fnp-3326	106	29	cover	cover	VERB
fnp-3326	106	30	slipping	slip	VERB
fnp-3326	106	31	with	with	ADP
fnp-3326	106	32	cytoseal	cytoseal	NOUN
fnp-3326	106	33	60	60	NUM
fnp-3326	106	34	mounting	mount	VERB
fnp-3326	106	35	media	medium	NOUN
fnp-3326	106	36	(	(	PUNCT
fnp-3326	106	37	thermo	thermo	NOUN
fnp-3326	106	38	fisher	fisher	PROPN
fnp-3326	106	39	scientific	scientific	PROPN
fnp-3326	106	40	)	)	PUNCT
fnp-3326	106	41	.	.	PUNCT
fnp-3326	107	1	quantifications	quantification	NOUN
fnp-3326	107	2	of	of	ADP
fnp-3326	107	3	the	the	DET
fnp-3326	107	4	blind	blind	ADV
fnp-3326	107	5	-	-	PUNCT
fnp-3326	107	6	coded	code	VERB
fnp-3326	107	7	th	th	NUM
fnp-3326	107	8	/	/	SYM
fnp-3326	107	9	nissl	nissl	NOUN
fnp-3326	107	10	-	-	PUNCT
fnp-3326	107	11	stained	stain	VERB
fnp-3326	107	12	slides	slide	NOUN
fnp-3326	107	13	were	be	AUX
fnp-3326	107	14	done	do	VERB
fnp-3326	107	15	using	use	VERB
fnp-3326	107	16	stereo	stereo	NOUN
fnp-3326	107	17	investigator	investigator	NOUN
fnp-3326	107	18	(	(	PUNCT
fnp-3326	107	19	version	version	NOUN
fnp-3326	107	20	2017.01.1	2017.01.1	NUM
fnp-3326	107	21	;	;	PUNCT
fnp-3326	107	22	mbf	mbf	NOUN
fnp-3326	107	23	bioscience	bioscience	NOUN
fnp-3326	107	24	,	,	PUNCT
fnp-3326	107	25	williams	williams	PROPN
fnp-3326	107	26	,	,	PUNCT
fnp-3326	107	27	vt	vt	PROPN
fnp-3326	107	28	,	,	PUNCT
fnp-3326	107	29	usa	usa	PROPN
fnp-3326	107	30	)	)	PUNCT
fnp-3326	107	31	on	on	ADP
fnp-3326	107	32	an	an	DET
fnp-3326	107	33	imager	imager	NOUN
fnp-3326	107	34	m2	m2	PROPN
fnp-3326	107	35	microscope	microscope	NOUN
fnp-3326	107	36	(	(	PUNCT
fnp-3326	107	37	zeiss	zeiss	PROPN
fnp-3326	107	38	)	)	PUNCT
fnp-3326	107	39	coupled	couple	VERB
fnp-3326	107	40	to	to	ADP
fnp-3326	107	41	a	a	DET
fnp-3326	107	42	computer	computer	NOUN
fnp-3326	107	43	.	.	PUNCT
fnp-3326	108	1	we	we	PRON
fnp-3326	108	2	analyzed	analyze	VERB
fnp-3326	108	3	5	5	NUM
fnp-3326	108	4	-	-	SYM
fnp-3326	108	5	7	7	NUM
fnp-3326	108	6	nigral	nigral	ADJ
fnp-3326	108	7	sections	section	NOUN
fnp-3326	108	8	per	per	ADP
fnp-3326	108	9	animal	animal	NOUN
fnp-3326	108	10	,	,	PUNCT
fnp-3326	108	11	and	and	CCONJ
fnp-3326	108	12	a	a	DET
fnp-3326	108	13	total	total	NOUN
fnp-3326	108	14	of	of	ADP
fnp-3326	108	15	7	7	NUM
fnp-3326	108	16	-	-	SYM
fnp-3326	108	17	8	8	NUM
fnp-3326	108	18	animals	animal	NOUN
fnp-3326	108	19	per	per	ADP
fnp-3326	108	20	treatment	treatment	NOUN
fnp-3326	108	21	group	group	NOUN
fnp-3326	108	22	.	.	PUNCT
fnp-3326	109	1	we	we	PRON
fnp-3326	109	2	outlined	outline	VERB
fnp-3326	109	3	the	the	DET
fnp-3326	109	4	substantia	substantia	NOUN
fnp-3326	109	5	nigra	nigra	PROPN
fnp-3326	109	6	pars	par	NOUN
fnp-3326	109	7	compacta	compacta	NOUN
fnp-3326	109	8	and	and	CCONJ
fnp-3326	109	9	counted	count	VERB
fnp-3326	109	10	every	every	DET
fnp-3326	109	11	th	th	NOUN
fnp-3326	109	12	-	-	PUNCT
fnp-3326	109	13	immunoreactive	immunoreactive	ADJ
fnp-3326	109	14	and	and	CCONJ
fnp-3326	109	15	nissl	nissl	ADJ
fnp-3326	109	16	-	-	PUNCT
fnp-3326	109	17	positive	positive	ADJ
fnp-3326	109	18	cell	cell	NOUN
fnp-3326	109	19	in	in	ADP
fnp-3326	109	20	that	that	DET
fnp-3326	109	21	area	area	NOUN
fnp-3326	109	22	(	(	PUNCT
fnp-3326	109	23	using	use	VERB
fnp-3326	109	24	a	a	DET
fnp-3326	109	25	counting	counting	NOUN
fnp-3326	109	26	frame	frame	NOUN
fnp-3326	109	27	of	of	ADP
fnp-3326	109	28	40	40	NUM
fnp-3326	109	29	µm	µm	NOUN
fnp-3326	109	30	x	x	SYM
fnp-3326	109	31	40	40	NUM
fnp-3326	109	32	µm	µm	NOUN
fnp-3326	109	33	,	,	PUNCT
fnp-3326	109	34	grid	grid	NOUN
fnp-3326	109	35	size	size	NOUN
fnp-3326	109	36	of	of	ADP
fnp-3326	109	37	140	140	NUM
fnp-3326	109	38	µm	µm	NOUN
fnp-3326	109	39	x	x	SYM
fnp-3326	109	40	140	140	NUM
fnp-3326	109	41	µm	µm	NOUN
fnp-3326	109	42	,	,	PUNCT
fnp-3326	109	43	a	a	DET
fnp-3326	109	44	guard	guard	NOUN
fnp-3326	109	45	zone	zone	NOUN
fnp-3326	109	46	of	of	ADP
fnp-3326	109	47	2	2	NUM
fnp-3326	109	48	µm	µm	NOUN
fnp-3326	109	49	and	and	CCONJ
fnp-3326	109	50	optical	optical	ADJ
fnp-3326	109	51	dissector	dissector	NOUN
fnp-3326	109	52	height	height	NOUN
fnp-3326	109	53	of	of	ADP
fnp-3326	109	54	20	20	NUM
fnp-3326	109	55	µm	µm	NOUN
fnp-3326	109	56	)	)	PUNCT
fnp-3326	109	57	and	and	CCONJ
fnp-3326	109	58	then	then	ADV
fnp-3326	109	59	computed	compute	VERB
fnp-3326	109	60	the	the	DET
fnp-3326	109	61	number	number	NOUN
fnp-3326	109	62	of	of	ADP
fnp-3326	109	63	cells	cell	NOUN
fnp-3326	109	64	per	per	ADP
fnp-3326	109	65	section	section	NOUN
fnp-3326	109	66	,	,	PUNCT
fnp-3326	109	67	generating	generate	VERB
fnp-3326	109	68	the	the	DET
fnp-3326	109	69	average	average	ADJ
fnp-3326	109	70	cell	cell	NOUN
fnp-3326	109	71	count	count	NOUN
fnp-3326	109	72	per	per	ADP
fnp-3326	109	73	animal	animal	NOUN
fnp-3326	109	74	.	.	PUNCT
fnp-3326	110	1	we	we	PRON
fnp-3326	110	2	then	then	ADV
fnp-3326	110	3	calculated	calculate	VERB
fnp-3326	110	4	the	the	DET
fnp-3326	110	5	average	average	ADJ
fnp-3326	110	6	count	count	NOUN
fnp-3326	110	7	of	of	ADP
fnp-3326	110	8	cells	cell	NOUN
fnp-3326	110	9	per	per	ADP
fnp-3326	110	10	treatment	treatment	NOUN
fnp-3326	110	11	group	group	NOUN
fnp-3326	110	12	and	and	CCONJ
fnp-3326	110	13	analyzed	analyze	VERB
fnp-3326	110	14	the	the	DET
fnp-3326	110	15	data	datum	NOUN
fnp-3326	110	16	using	use	VERB
fnp-3326	110	17	unpaired	unpaired	ADJ
fnp-3326	110	18	student	student	NOUN
fnp-3326	110	19	’s	’s	PART
fnp-3326	110	20	t	t	PROPN
fnp-3326	110	21	-	-	PUNCT
fnp-3326	110	22	test	test	NOUN
fnp-3326	110	23	after	after	ADP
fnp-3326	110	24	confirming	confirm	VERB
fnp-3326	110	25	normality	normality	NOUN
fnp-3326	110	26	and	and	CCONJ
fnp-3326	110	27	homoscedasticity	homoscedasticity	NOUN
fnp-3326	110	28	in	in	ADP
fnp-3326	110	29	prism	prism	NOUN
fnp-3326	110	30	7.0	7.0	NUM
fnp-3326	110	31	(	(	PUNCT
fnp-3326	110	32	graphpad	graphpad	NOUN
fnp-3326	110	33	software	software	NOUN
fnp-3326	110	34	)	)	PUNCT
fnp-3326	110	35	.	.	PUNCT
fnp-3326	111	1	imaging	imaging	NOUN
fnp-3326	111	2	and	and	CCONJ
fnp-3326	111	3	stereological	stereological	ADJ
fnp-3326	111	4	quantification	quantification	NOUN
fnp-3326	111	5	of	of	ADP
fnp-3326	111	6	αsyn	αsyn	ADJ
fnp-3326	111	7	deposits	deposit	NOUN
fnp-3326	111	8	in	in	ADP
fnp-3326	111	9	enteric	enteric	ADJ
fnp-3326	111	10	nervous	nervous	ADJ
fnp-3326	111	11	system	system	NOUN
fnp-3326	111	12	imaging	imaging	NOUN
fnp-3326	111	13	and	and	CCONJ
fnp-3326	111	14	stereological	stereological	ADJ
fnp-3326	111	15	quantification	quantification	NOUN
fnp-3326	111	16	were	be	AUX
fnp-3326	111	17	performed	perform	VERB
fnp-3326	111	18	on	on	ADP
fnp-3326	111	19	a	a	DET
fnp-3326	111	20	zeiss	zeiss	PROPN
fnp-3326	111	21	axio	axio	PROPN
fnp-3326	111	22	imager	imager	PROPN
fnp-3326	111	23	z2	z2	PROPN
fnp-3326	111	24	fluorescence	fluorescence	NOUN
fnp-3326	111	25	microscope	microscope	NOUN
fnp-3326	111	26	(	(	PUNCT
fnp-3326	111	27	carl	carl	PROPN
fnp-3326	111	28	zeiss	zeiss	PROPN
fnp-3326	111	29	ag	ag	PROPN
fnp-3326	111	30	,	,	PUNCT
fnp-3326	111	31	jena	jena	PROPN
fnp-3326	111	32	,	,	PUNCT
fnp-3326	111	33	germany	germany	PROPN
fnp-3326	111	34	)	)	PUNCT
fnp-3326	111	35	.	.	PUNCT
fnp-3326	112	1	leica	leica	PROPN
fnp-3326	112	2	tcs	tcs	PROPN
fnp-3326	112	3	sp5	sp5	VERB
fnp-3326	112	4	confocal	confocal	ADJ
fnp-3326	112	5	system	system	NOUN
fnp-3326	112	6	using	use	VERB
fnp-3326	112	7	an	an	DET
fnp-3326	112	8	hcx	hcx	NOUN
fnp-3326	112	9	pl	pl	X
fnp-3326	112	10	apo	apo	PROPN
fnp-3326	112	11	cs	cs	PROPN
fnp-3326	112	12	40x	40x	PROPN
fnp-3326	112	13	1.3	1.3	NUM
fnp-3326	112	14	oil	oil	NOUN
fnp-3326	112	15	uv	uv	NOUN
fnp-3326	112	16	or	or	CCONJ
fnp-3326	112	17	an	an	DET
fnp-3326	112	18	hcx	hcx	NOUN
fnp-3326	112	19	pl	pl	X
fnp-3326	112	20	apo	apo	PROPN
fnp-3326	112	21	lb	lb	PROPN
fnp-3326	112	22	63x	63x	PROPN
fnp-3326	112	23	1.4	1.4	NUM
fnp-3326	112	24	oil	oil	NOUN
fnp-3326	112	25	uv	uv	NOUN
fnp-3326	112	26	objective	objective	NOUN
fnp-3326	112	27	was	be	AUX
fnp-3326	112	28	utilized	utilize	VERB
fnp-3326	112	29	for	for	ADP
fnp-3326	112	30	image	image	NOUN
fnp-3326	112	31	recording	recording	NOUN
fnp-3326	112	32	.	.	PUNCT
fnp-3326	113	1	accumulation	accumulation	NOUN
fnp-3326	113	2	of	of	ADP
fnp-3326	113	3	αsyn	αsyn	NOUN
fnp-3326	113	4	in	in	ADP
fnp-3326	113	5	the	the	DET
fnp-3326	113	6	ens	ens	NOUN
fnp-3326	113	7	(	(	PUNCT
fnp-3326	113	8	i.e.	i.e.	X
fnp-3326	113	9	,	,	PUNCT
fnp-3326	113	10	punctate	punctate	VERB
fnp-3326	113	11	intracellular	intracellular	ADJ
fnp-3326	113	12	bodies	body	NOUN
fnp-3326	113	13	/	/	SYM
fnp-3326	113	14	features	feature	NOUN
fnp-3326	113	15	)	)	PUNCT
fnp-3326	113	16	was	be	AUX
fnp-3326	113	17	assessed	assess	VERB
fnp-3326	113	18	on	on	ADP
fnp-3326	113	19	a	a	DET
fnp-3326	113	20	random	random	ADJ
fnp-3326	113	21	set	set	NOUN
fnp-3326	113	22	of	of	ADP
fnp-3326	113	23	3	3	NUM
fnp-3326	113	24	adjacent	adjacent	ADJ
fnp-3326	113	25	35	35	NUM
fnp-3326	113	26	µm	µm	ADP
fnp-3326	113	27	thick	thick	ADJ
fnp-3326	113	28	,	,	PUNCT
fnp-3326	113	29	αsyn	αsyn	NOUN
fnp-3326	113	30	-	-	PUNCT
fnp-3326	113	31	immunostained	immunostaine	VERB
fnp-3326	113	32	sections	section	NOUN
fnp-3326	113	33	comprising	comprise	VERB
fnp-3326	113	34	the	the	DET
fnp-3326	113	35	myenteric	myenteric	ADJ
fnp-3326	113	36	and	and	CCONJ
fnp-3326	113	37	submucosal	submucosal	ADJ
fnp-3326	113	38	neuronal	neuronal	ADJ
fnp-3326	113	39	plexuses	plexus	NOUN
fnp-3326	113	40	.	.	PUNCT
fnp-3326	114	1	analysis	analysis	NOUN
fnp-3326	114	2	was	be	AUX
fnp-3326	114	3	performed	perform	VERB
fnp-3326	114	4	with	with	ADP
fnp-3326	114	5	the	the	DET
fnp-3326	114	6	aid	aid	NOUN
fnp-3326	114	7	of	of	ADP
fnp-3326	114	8	a	a	DET
fnp-3326	114	9	stereology	stereology	NOUN
fnp-3326	114	10	software	software	NOUN
fnp-3326	114	11	(	(	PUNCT
fnp-3326	114	12	stereo	stereo	NOUN
fnp-3326	114	13	investigator	investigator	NOUN
fnp-3326	114	14	10	10	NUM
fnp-3326	114	15	,	,	PUNCT
fnp-3326	114	16	mbf	mbf	NOUN
fnp-3326	114	17	bioscience	bioscience	NOUN
fnp-3326	114	18	,	,	PUNCT
fnp-3326	114	19	williams	williams	PROPN
fnp-3326	114	20	,	,	PUNCT
fnp-3326	114	21	vt	vt	PROPN
fnp-3326	114	22	,	,	PUNCT
fnp-3326	114	23	usa	usa	PROPN
fnp-3326	114	24	)	)	PUNCT
fnp-3326	114	25	as	as	SCONJ
fnp-3326	114	26	described	describe	VERB
fnp-3326	114	27	previously	previously	ADV
fnp-3326	114	28	[	[	X
fnp-3326	114	29	45	45	NUM
fnp-3326	114	30	]	]	PUNCT
fnp-3326	114	31	.	.	PUNCT
fnp-3326	115	1	in	in	ADP
fnp-3326	115	2	the	the	DET
fnp-3326	115	3	myenteric	myenteric	ADJ
fnp-3326	115	4	plexus	plexus	NOUN
fnp-3326	115	5	ganglion	ganglion	NOUN
fnp-3326	115	6	,	,	PUNCT
fnp-3326	115	7	volume	volume	NOUN
fnp-3326	115	8	was	be	AUX
fnp-3326	115	9	defined	define	VERB
fnp-3326	115	10	by	by	ADP
fnp-3326	115	11	multiple	multiple	ADJ
fnp-3326	115	12	outlined	outline	VERB
fnp-3326	115	13	plexuses	plexus	NOUN
fnp-3326	115	14	containing	contain	VERB
fnp-3326	115	15	a	a	DET
fnp-3326	115	16	range	range	NOUN
fnp-3326	115	17	of	of	ADP
fnp-3326	115	18	5	5	NUM
fnp-3326	115	19	-	-	SYM
fnp-3326	115	20	20	20	NUM
fnp-3326	115	21	neuronal	neuronal	ADJ
fnp-3326	115	22	cells	cell	NOUN
fnp-3326	115	23	and	and	CCONJ
fnp-3326	115	24	quantified	quantify	VERB
fnp-3326	115	25	by	by	ADP
fnp-3326	115	26	the	the	DET
fnp-3326	115	27	optical	optical	ADJ
fnp-3326	115	28	fraction	fraction	NOUN
fnp-3326	115	29	fractionator	fractionator	NOUN
fnp-3326	115	30	technique	technique	NOUN
fnp-3326	115	31	.	.	PUNCT
fnp-3326	116	1	in	in	ADP
fnp-3326	116	2	contrast	contrast	NOUN
fnp-3326	116	3	to	to	ADP
fnp-3326	116	4	the	the	DET
fnp-3326	116	5	myenteric	myenteric	ADJ
fnp-3326	116	6	plexus	plexus	NOUN
fnp-3326	116	7	,	,	PUNCT
fnp-3326	116	8	the	the	DET
fnp-3326	116	9	submucosa	submucosa	NOUN
fnp-3326	116	10	consists	consist	VERB
fnp-3326	116	11	of	of	ADP
fnp-3326	116	12	compact	compact	ADJ
fnp-3326	116	13	plexuses	plexus	NOUN
fnp-3326	116	14	with	with	ADP
fnp-3326	116	15	1	1	NUM
fnp-3326	116	16	-	-	SYM
fnp-3326	116	17	5	5	NUM
fnp-3326	116	18	cells	cell	NOUN
fnp-3326	116	19	including	include	VERB
fnp-3326	116	20	interconnecting	interconnect	VERB
fnp-3326	116	21	neurites	neurite	NOUN
fnp-3326	116	22	.	.	PUNCT
fnp-3326	117	1	therefore	therefore	ADV
fnp-3326	117	2	,	,	PUNCT
fnp-3326	117	3	the	the	DET
fnp-3326	117	4	entire	entire	ADJ
fnp-3326	117	5	submucosa	submucosa	NOUN
fnp-3326	117	6	was	be	AUX
fnp-3326	117	7	set	set	VERB
fnp-3326	117	8	as	as	ADP
fnp-3326	117	9	region	region	NOUN
fnp-3326	117	10	of	of	ADP
fnp-3326	117	11	interest	interest	NOUN
fnp-3326	117	12	,	,	PUNCT
fnp-3326	117	13	analyzed	analyze	VERB
fnp-3326	117	14	with	with	ADP
fnp-3326	117	15	the	the	DET
fnp-3326	117	16	area	area	NOUN
fnp-3326	117	17	fraction	fraction	NOUN
fnp-3326	117	18	fractionator	fractionator	NOUN
fnp-3326	117	19	technique	technique	NOUN
fnp-3326	117	20	.	.	PUNCT
fnp-3326	118	1	results	result	NOUN
fnp-3326	118	2	of	of	ADP
fnp-3326	118	3	the	the	DET
fnp-3326	118	4	submucosal	submucosal	NOUN
fnp-3326	118	5	plexus	plexus	NOUN
fnp-3326	118	6	are	be	AUX
fnp-3326	118	7	displayed	display	VERB
fnp-3326	118	8	by	by	ADP
fnp-3326	118	9	percent	percent	NOUN
fnp-3326	118	10	area	area	NOUN
fnp-3326	118	11	containing	contain	VERB
fnp-3326	118	12	αsyn	αsyn	ADJ
fnp-3326	118	13	deposits	deposit	NOUN
fnp-3326	118	14	.	.	PUNCT
fnp-3326	119	1	for	for	ADP
fnp-3326	119	2	the	the	DET
fnp-3326	119	3	il-10	il-10	DET
fnp-3326	119	4	experiment	experiment	NOUN
fnp-3326	119	5	,	,	PUNCT
fnp-3326	119	6	αsyn	αsyn	ADJ
fnp-3326	119	7	positive	positive	ADJ
fnp-3326	119	8	inclusions	inclusion	NOUN
fnp-3326	119	9	from	from	ADP
fnp-3326	119	10	immunofluorescence	immunofluorescence	NOUN
fnp-3326	119	11	images	image	NOUN
fnp-3326	119	12	were	be	AUX
fnp-3326	119	13	counted	count	VERB
fnp-3326	119	14	for	for	ADP
fnp-3326	119	15	each	each	DET
fnp-3326	119	16	image	image	NOUN
fnp-3326	119	17	.	.	PUNCT
fnp-3326	120	1	inclusion	inclusion	NOUN
fnp-3326	120	2	body	body	NOUN
fnp-3326	120	3	-	-	PUNCT
fnp-3326	120	4	like	like	ADJ
fnp-3326	120	5	features	feature	NOUN
fnp-3326	120	6	were	be	AUX
fnp-3326	120	7	filtered	filter	VERB
fnp-3326	120	8	based	base	VERB
fnp-3326	120	9	on	on	ADP
fnp-3326	120	10	having	have	VERB
fnp-3326	120	11	a	a	DET
fnp-3326	120	12	size	size	NOUN
fnp-3326	120	13	between	between	ADP
fnp-3326	120	14	12	12	NUM
fnp-3326	120	15	and	and	CCONJ
fnp-3326	120	16	50000	50000	NUM
fnp-3326	120	17	pixels	pixel	NOUN
fnp-3326	120	18	and	and	CCONJ
fnp-3326	120	19	a	a	DET
fnp-3326	120	20	minimal	minimal	ADJ
fnp-3326	120	21	intensity	intensity	NOUN
fnp-3326	120	22	value	value	NOUN
fnp-3326	120	23	greater	great	ADJ
fnp-3326	120	24	than	than	ADP
fnp-3326	120	25	300	300	NUM
fnp-3326	120	26	.	.	PUNCT
fnp-3326	121	1	the	the	DET
fnp-3326	121	2	filtering	filter	VERB
fnp-3326	121	3	step	step	NOUN
fnp-3326	121	4	was	be	AUX
fnp-3326	121	5	performed	perform	VERB
fnp-3326	121	6	to	to	PART
fnp-3326	121	7	exclude	exclude	VERB
fnp-3326	121	8	small	small	ADJ
fnp-3326	121	9	background	background	NOUN
fnp-3326	121	10	features	feature	NOUN
fnp-3326	121	11	and	and	CCONJ
fnp-3326	121	12	macrophages	macrophage	NOUN
fnp-3326	121	13	(	(	PUNCT
fnp-3326	121	14	very	very	ADV
fnp-3326	121	15	large	large	ADJ
fnp-3326	121	16	spots	spot	NOUN
fnp-3326	121	17	)	)	PUNCT
fnp-3326	121	18	.	.	PUNCT
fnp-3326	122	1	the	the	DET
fnp-3326	122	2	counts	count	NOUN
fnp-3326	122	3	were	be	AUX
fnp-3326	122	4	then	then	ADV
fnp-3326	122	5	aggregated	aggregate	VERB
fnp-3326	122	6	to	to	ADP
fnp-3326	122	7	the	the	DET
fnp-3326	122	8	animal	animal	NOUN
fnp-3326	122	9	level	level	NOUN
fnp-3326	122	10	by	by	ADP
fnp-3326	122	11	summing	sum	VERB
fnp-3326	122	12	the	the	DET
fnp-3326	122	13	inclusion	inclusion	NOUN
fnp-3326	122	14	feature	feature	NOUN
fnp-3326	122	15	counts	count	NOUN
fnp-3326	122	16	of	of	ADP
fnp-3326	122	17	all	all	DET
fnp-3326	122	18	images	image	NOUN
fnp-3326	122	19	per	per	ADP
fnp-3326	122	20	animal	animal	NOUN
fnp-3326	122	21	and	and	CCONJ
fnp-3326	122	22	then	then	ADV
fnp-3326	122	23	normalizing	normalize	VERB
fnp-3326	122	24	for	for	ADP
fnp-3326	122	25	(	(	PUNCT
fnp-3326	122	26	i.e.	i.e.	X
fnp-3326	122	27	,	,	PUNCT
fnp-3326	122	28	dividing	divide	VERB
fnp-3326	122	29	by	by	ADP
fnp-3326	122	30	)	)	PUNCT
fnp-3326	122	31	the	the	DET
fnp-3326	122	32	number	number	NOUN
fnp-3326	122	33	of	of	ADP
fnp-3326	122	34	images	image	NOUN
fnp-3326	122	35	for	for	ADP
fnp-3326	122	36	a	a	DET
fnp-3326	122	37	given	give	VERB
fnp-3326	122	38	animal	animal	NOUN
fnp-3326	122	39	.	.	PUNCT
fnp-3326	123	1	upon	upon	SCONJ
fnp-3326	123	2	exploratory	exploratory	ADJ
fnp-3326	123	3	data	datum	NOUN
fnp-3326	123	4	analysis	analysis	NOUN
fnp-3326	123	5	two	two	NUM
fnp-3326	123	6	mice	mouse	NOUN
fnp-3326	123	7	were	be	AUX
fnp-3326	123	8	excluded	exclude	VERB
fnp-3326	123	9	:	:	PUNCT
fnp-3326	123	10	one	one	NUM
fnp-3326	123	11	mouse	mouse	NOUN
fnp-3326	123	12	because	because	SCONJ
fnp-3326	123	13	it	it	PRON
fnp-3326	123	14	only	only	ADV
fnp-3326	123	15	had	have	VERB
fnp-3326	123	16	one	one	NUM
fnp-3326	123	17	image	image	NOUN
fnp-3326	123	18	(	(	PUNCT
fnp-3326	123	19	technical	technical	ADJ
fnp-3326	123	20	outlier	outlier	NOUN
fnp-3326	123	21	,	,	PUNCT
fnp-3326	123	22	missing	miss	VERB
fnp-3326	123	23	data	datum	NOUN
fnp-3326	123	24	point	point	NOUN
fnp-3326	123	25	;	;	PUNCT
fnp-3326	123	26	repeating	repeat	VERB
fnp-3326	123	27	the	the	DET
fnp-3326	123	28	staining	staining	NOUN
fnp-3326	123	29	for	for	ADP
fnp-3326	123	30	this	this	DET
fnp-3326	123	31	one	one	NUM
fnp-3326	123	32	mouse	mouse	NOUN
fnp-3326	123	33	would	would	AUX
fnp-3326	123	34	have	have	AUX
fnp-3326	123	35	required	require	VERB
fnp-3326	123	36	re	re	VERB
fnp-3326	123	37	-	-	VERB
fnp-3326	123	38	staining	stain	VERB
fnp-3326	123	39	the	the	DET
fnp-3326	123	40	entire	entire	ADJ
fnp-3326	123	41	cohort	cohort	NOUN
fnp-3326	123	42	in	in	ADP
fnp-3326	123	43	order	order	NOUN
fnp-3326	123	44	to	to	PART
fnp-3326	123	45	be	be	AUX
fnp-3326	123	46	consistent	consistent	ADJ
fnp-3326	123	47	with	with	ADP
fnp-3326	123	48	staining	stain	VERB
fnp-3326	123	49	conditions	condition	NOUN
fnp-3326	123	50	for	for	ADP
fnp-3326	123	51	quantification	quantification	NOUN
fnp-3326	123	52	;	;	PUNCT
fnp-3326	123	53	this	this	PRON
fnp-3326	123	54	was	be	AUX
fnp-3326	123	55	unnecessary	unnecessary	ADJ
fnp-3326	123	56	after	after	ADP
fnp-3326	123	57	statistical	statistical	ADJ
fnp-3326	123	58	analysis	analysis	NOUN
fnp-3326	123	59	)	)	PUNCT
fnp-3326	123	60	and	and	CCONJ
fnp-3326	123	61	another	another	PRON
fnp-3326	123	62	due	due	ADP
fnp-3326	123	63	to	to	ADP
fnp-3326	123	64	it	it	PRON
fnp-3326	123	65	being	be	AUX
fnp-3326	123	66	an	an	DET
fnp-3326	123	67	outlier	outlier	NOUN
fnp-3326	123	68	,	,	PUNCT
fnp-3326	123	69	based	base	VERB
fnp-3326	123	70	on	on	ADP
fnp-3326	123	71	its	its	PRON
fnp-3326	123	72	infiltration	infiltration	NOUN
fnp-3326	123	73	score	score	NOUN
fnp-3326	123	74	and	and	CCONJ
fnp-3326	123	75	image	image	NOUN
fnp-3326	123	76	data	datum	NOUN
fnp-3326	123	77	(	(	PUNCT
fnp-3326	123	78	i.e.	i.e.	X
fnp-3326	123	79	,	,	PUNCT
fnp-3326	123	80	in	in	ADP
fnp-3326	123	81	contrast	contrast	NOUN
fnp-3326	123	82	to	to	ADP
fnp-3326	123	83	the	the	DET
fnp-3326	123	84	other	other	ADJ
fnp-3326	123	85	mice	mouse	NOUN
fnp-3326	123	86	that	that	PRON
fnp-3326	123	87	had	have	AUX
fnp-3326	123	88	received	receive	VERB
fnp-3326	123	89	dss	dss	NOUN
fnp-3326	123	90	,	,	PUNCT
fnp-3326	123	91	this	this	DET
fnp-3326	123	92	mouse	mouse	NOUN
fnp-3326	123	93	did	do	AUX
fnp-3326	123	94	not	not	PART
fnp-3326	123	95	show	show	VERB
fnp-3326	123	96	signs	sign	NOUN
fnp-3326	123	97	of	of	ADP
fnp-3326	123	98	inflammation	inflammation	NOUN
fnp-3326	123	99	or	or	CCONJ
fnp-3326	123	100	colonic	colonic	ADJ
fnp-3326	123	101	tissue	tissue	NOUN
fnp-3326	123	102	damage	damage	NOUN
fnp-3326	123	103	that	that	PRON
fnp-3326	123	104	is	be	AUX
fnp-3326	123	105	normally	normally	ADV
fnp-3326	123	106	induced	induce	VERB
fnp-3326	123	107	by	by	ADP
fnp-3326	123	108	dss	dss	NOUN
fnp-3326	123	109	;	;	PUNCT
fnp-3326	123	110	it	it	PRON
fnp-3326	123	111	could	could	AUX
fnp-3326	123	112	not	not	PART
fnp-3326	123	113	be	be	AUX
fnp-3326	123	114	determined	determine	VERB
fnp-3326	123	115	if	if	SCONJ
fnp-3326	123	116	that	that	DET
fnp-3326	123	117	mouse	mouse	NOUN
fnp-3326	123	118	was	be	AUX
fnp-3326	123	119	correctly	correctly	ADV
fnp-3326	123	120	dosed	dose	VERB
fnp-3326	123	121	with	with	ADP
fnp-3326	123	122	dss	dss	NOUN
fnp-3326	123	123	and	and	CCONJ
fnp-3326	123	124	thus	thus	ADV
fnp-3326	123	125	it	it	PRON
fnp-3326	123	126	was	be	AUX
fnp-3326	123	127	excluded	exclude	VERB
fnp-3326	123	128	from	from	ADP
fnp-3326	123	129	the	the	DET
fnp-3326	123	130	analysis	analysis	NOUN
fnp-3326	123	131	)	)	PUNCT
fnp-3326	123	132	.	.	PUNCT
fnp-3326	124	1	quantification	quantification	NOUN
fnp-3326	124	2	of	of	ADP
fnp-3326	124	3	leukocytes	leukocyte	NOUN
fnp-3326	124	4	infiltration	infiltration	NOUN
fnp-3326	124	5	to	to	PART
fnp-3326	124	6	determine	determine	VERB
fnp-3326	124	7	the	the	DET
fnp-3326	124	8	leukocyte	leukocyte	NOUN
fnp-3326	124	9	covered	cover	VERB
fnp-3326	124	10	area	area	NOUN
fnp-3326	124	11	in	in	ADP
fnp-3326	124	12	the	the	DET
fnp-3326	124	13	colon	colon	NOUN
fnp-3326	124	14	after	after	ADP
fnp-3326	124	15	lps	lps	PROPN
fnp-3326	124	16	or	or	CCONJ
fnp-3326	124	17	dss	dss	NOUN
fnp-3326	124	18	application	application	NOUN
fnp-3326	124	19	,	,	PUNCT
fnp-3326	124	20	three	three	NUM
fnp-3326	124	21	adjacent	adjacent	ADJ
fnp-3326	124	22	hematoxylin	hematoxylin	NOUN
fnp-3326	124	23	-	-	PUNCT
fnp-3326	124	24	stained	stain	VERB
fnp-3326	124	25	sections	section	NOUN
fnp-3326	124	26	were	be	AUX
fnp-3326	124	27	quantified	quantify	VERB
fnp-3326	124	28	.	.	PUNCT
fnp-3326	125	1	total	total	ADJ
fnp-3326	125	2	area	area	NOUN
fnp-3326	125	3	of	of	ADP
fnp-3326	125	4	colon	colon	NOUN
fnp-3326	125	5	sections	section	NOUN
fnp-3326	125	6	and	and	CCONJ
fnp-3326	125	7	localizations	localization	NOUN
fnp-3326	125	8	of	of	ADP
fnp-3326	125	9	leukocyte	leukocyte	ADJ
fnp-3326	125	10	assemblies	assembly	NOUN
fnp-3326	125	11	within	within	ADP
fnp-3326	125	12	the	the	DET
fnp-3326	125	13	tissue	tissue	NOUN
fnp-3326	125	14	architecture	architecture	NOUN
fnp-3326	125	15	were	be	AUX
fnp-3326	125	16	identified	identify	VERB
fnp-3326	125	17	and	and	CCONJ
fnp-3326	125	18	outlined	outline	VERB
fnp-3326	125	19	utilizing	utilize	VERB
fnp-3326	125	20	a	a	DET
fnp-3326	125	21	stereology	stereology	NOUN
fnp-3326	125	22	software	software	NOUN
fnp-3326	125	23	(	(	PUNCT
fnp-3326	125	24	stereo	stereo	NOUN
fnp-3326	125	25	investigator	investigator	NOUN
fnp-3326	125	26	6	6	NUM
fnp-3326	125	27	,	,	PUNCT
fnp-3326	125	28	mbf	mbf	NOUN
fnp-3326	125	29	bioscience	bioscience	NOUN
fnp-3326	125	30	,	,	PUNCT
fnp-3326	125	31	williams	williams	PROPN
fnp-3326	125	32	,	,	PUNCT
fnp-3326	125	33	vt	vt	PROPN
fnp-3326	125	34	,	,	PUNCT
fnp-3326	125	35	usa	usa	PROPN
fnp-3326	125	36	)	)	PUNCT
fnp-3326	125	37	.	.	PUNCT
fnp-3326	126	1	percentage	percentage	NOUN
fnp-3326	126	2	of	of	ADP
fnp-3326	126	3	leukocyte	leukocyte	NOUN
fnp-3326	126	4	covered	cover	VERB
fnp-3326	126	5	area	area	NOUN
fnp-3326	126	6	has	have	AUX
fnp-3326	126	7	been	be	AUX
fnp-3326	126	8	set	set	VERB
fnp-3326	126	9	in	in	ADP
fnp-3326	126	10	proportion	proportion	NOUN
fnp-3326	126	11	to	to	ADP
fnp-3326	126	12	total	total	ADJ
fnp-3326	126	13	area	area	NOUN
fnp-3326	126	14	of	of	ADP
fnp-3326	126	15	the	the	DET
fnp-3326	126	16	analyzed	analyze	VERB
fnp-3326	126	17	colon	colon	NOUN
fnp-3326	126	18	section	section	NOUN
fnp-3326	126	19	,	,	PUNCT
fnp-3326	126	20	e.g.	e.g.	ADV
fnp-3326	126	21	,	,	PUNCT
fnp-3326	126	22	to	to	ADP
fnp-3326	126	23	at	at	ADP
fnp-3326	126	24	least	least	ADJ
fnp-3326	126	25	the	the	DET
fnp-3326	126	26	length	length	NOUN
fnp-3326	126	27	of	of	ADP
fnp-3326	126	28	1	1	NUM
fnp-3326	126	29	cm	cm	NOUN
fnp-3326	126	30	of	of	ADP
fnp-3326	126	31	proximal	proximal	ADJ
fnp-3326	126	32	colon	colon	NOUN
fnp-3326	126	33	.	.	PUNCT
fnp-3326	127	1	for	for	ADP
fnp-3326	127	2	the	the	DET
fnp-3326	127	3	il-10	il-10	DET
fnp-3326	127	4	experiment	experiment	NOUN
fnp-3326	127	5	,	,	PUNCT
fnp-3326	127	6	hematoxylin	hematoxylin	NOUN
fnp-3326	127	7	-	-	PUNCT
fnp-3326	127	8	stained	stain	VERB
fnp-3326	127	9	colon	colon	NOUN
fnp-3326	127	10	slices	slice	NOUN
fnp-3326	127	11	were	be	AUX
fnp-3326	127	12	examined	examine	VERB
fnp-3326	127	13	by	by	ADP
fnp-3326	127	14	an	an	DET
fnp-3326	127	15	expert	expert	ADJ
fnp-3326	127	16	pathologist	pathologist	NOUN
fnp-3326	127	17	blinded	blind	VERB
fnp-3326	127	18	to	to	ADP
fnp-3326	127	19	treatment	treatment	NOUN
fnp-3326	127	20	conditions	condition	NOUN
fnp-3326	127	21	.	.	PUNCT
fnp-3326	128	1	a	a	DET
fnp-3326	128	2	score	score	NOUN
fnp-3326	128	3	of	of	ADP
fnp-3326	128	4	0	0	NUM
fnp-3326	128	5	-	-	SYM
fnp-3326	128	6	3	3	NUM
fnp-3326	128	7	was	be	AUX
fnp-3326	128	8	assigned	assign	VERB
fnp-3326	128	9	to	to	ADP
fnp-3326	128	10	each	each	DET
fnp-3326	128	11	section	section	NOUN
fnp-3326	128	12	for	for	ADP
fnp-3326	128	13	each	each	PRON
fnp-3326	128	14	of	of	ADP
fnp-3326	128	15	the	the	DET
fnp-3326	128	16	3	3	NUM
fnp-3326	128	17	layers	layer	NOUN
fnp-3326	128	18	lamina	lamina	PROPN
fnp-3326	128	19	propria	propria	PROPN
fnp-3326	128	20	,	,	PUNCT
fnp-3326	128	21	submucosa	submucosa	PROPN
fnp-3326	128	22	and	and	CCONJ
fnp-3326	128	23	muscularis	muscularis	NOUN
fnp-3326	128	24	based	base	VERB
fnp-3326	128	25	on	on	ADP
fnp-3326	128	26	the	the	DET
fnp-3326	128	27	degree	degree	NOUN
fnp-3326	128	28	of	of	ADP
fnp-3326	128	29	inflammatory	inflammatory	ADJ
fnp-3326	128	30	infiltration	infiltration	NOUN
fnp-3326	128	31	.	.	PUNCT
fnp-3326	129	1	a	a	DET
fnp-3326	129	2	score	score	NOUN
fnp-3326	129	3	of	of	ADP
fnp-3326	129	4	0	0	NUM
fnp-3326	129	5	denoted	denote	VERB
fnp-3326	129	6	no	no	DET
fnp-3326	129	7	inflammation	inflammation	NOUN
fnp-3326	129	8	and	and	CCONJ
fnp-3326	129	9	a	a	DET
fnp-3326	129	10	score	score	NOUN
fnp-3326	129	11	of	of	ADP
fnp-3326	129	12	3	3	NUM
fnp-3326	129	13	indicated	indicate	VERB
fnp-3326	129	14	extensive	extensive	ADJ
fnp-3326	129	15	infiltration	infiltration	NOUN
fnp-3326	129	16	.	.	PUNCT
fnp-3326	130	1	the	the	DET
fnp-3326	130	2	mean	mean	NOUN
fnp-3326	130	3	of	of	ADP
fnp-3326	130	4	the	the	DET
fnp-3326	130	5	values	value	NOUN
fnp-3326	130	6	for	for	ADP
fnp-3326	130	7	all	all	DET
fnp-3326	130	8	3	3	NUM
fnp-3326	130	9	layers	layer	NOUN
fnp-3326	130	10	was	be	AUX
fnp-3326	130	11	taken	take	VERB
fnp-3326	130	12	as	as	ADP
fnp-3326	130	13	the	the	DET
fnp-3326	130	14	final	final	ADJ
fnp-3326	130	15	measure	measure	NOUN
fnp-3326	130	16	of	of	ADP
fnp-3326	130	17	leukocyte	leukocyte	ADJ
fnp-3326	130	18	infiltration	infiltration	NOUN
fnp-3326	130	19	per	per	ADP
fnp-3326	130	20	mouse	mouse	NOUN
fnp-3326	130	21	.	.	PUNCT
fnp-3326	131	1	quantification	quantification	NOUN
fnp-3326	131	2	of	of	ADP
fnp-3326	131	3	iba-1	iba-1	PUNCT
fnp-3326	131	4	/	/	SYM
fnp-3326	131	5	αsyn	αsyn	NOUN
fnp-3326	131	6	-	-	PUNCT
fnp-3326	131	7	double	double	ADJ
fnp-3326	131	8	positive	positive	ADJ
fnp-3326	131	9	macrophages	macrophage	NOUN
fnp-3326	131	10	the	the	DET
fnp-3326	131	11	number	number	NOUN
fnp-3326	131	12	of	of	ADP
fnp-3326	131	13	iba-1	iba-1	PUNCT
fnp-3326	131	14	/	/	SYM
fnp-3326	131	15	αsyn	αsyn	NOUN
fnp-3326	131	16	-	-	PUNCT
fnp-3326	131	17	double	double	ADJ
fnp-3326	131	18	positive	positive	ADJ
fnp-3326	131	19	cells	cell	NOUN
fnp-3326	131	20	was	be	AUX
fnp-3326	131	21	evaluated	evaluate	VERB
fnp-3326	131	22	by	by	ADP
fnp-3326	131	23	quantification	quantification	NOUN
fnp-3326	131	24	of	of	ADP
fnp-3326	131	25	10	10	NUM
fnp-3326	131	26	random	random	ADJ
fnp-3326	131	27	regions	region	NOUN
fnp-3326	131	28	in	in	ADP
fnp-3326	131	29	2	2	NUM
fnp-3326	131	30	adjacent	adjacent	ADJ
fnp-3326	131	31	sections	section	NOUN
fnp-3326	131	32	of	of	ADP
fnp-3326	131	33	the	the	DET
fnp-3326	131	34	proximal	proximal	ADJ
fnp-3326	131	35	colon	colon	NOUN
fnp-3326	131	36	.	.	PUNCT
fnp-3326	132	1	the	the	DET
fnp-3326	132	2	region	region	NOUN
fnp-3326	132	3	of	of	ADP
fnp-3326	132	4	interest	interest	NOUN
fnp-3326	132	5	was	be	AUX
fnp-3326	132	6	set	set	VERB
fnp-3326	132	7	to	to	PART
fnp-3326	132	8	contain	contain	VERB
fnp-3326	132	9	the	the	DET
fnp-3326	132	10	myenteric	myenteric	ADJ
fnp-3326	132	11	plexus	plexus	NOUN
fnp-3326	132	12	/	/	SYM
fnp-3326	132	13	circular	circular	ADJ
fnp-3326	132	14	muscle	muscle	NOUN
fnp-3326	132	15	layer	layer	NOUN
fnp-3326	132	16	and	and	CCONJ
fnp-3326	132	17	the	the	DET
fnp-3326	132	18	submucosal	submucosal	NOUN
fnp-3326	132	19	plexus	plexus	NOUN
fnp-3326	132	20	.	.	PUNCT
fnp-3326	133	1	scoring	scoring	NOUN
fnp-3326	133	2	of	of	ADP
fnp-3326	133	3	pser129	pser129	PROPN
fnp-3326	133	4	pathology	pathology	NOUN
fnp-3326	133	5	and	and	CCONJ
fnp-3326	133	6	brain	brain	NOUN
fnp-3326	133	7	heatmap	heatmap	NOUN
fnp-3326	133	8	we	we	PRON
fnp-3326	133	9	evaluated	evaluate	VERB
fnp-3326	133	10	pser129	pser129	PROPN
fnp-3326	133	11	pathology	pathology	NOUN
fnp-3326	133	12	on	on	ADP
fnp-3326	133	13	a	a	DET
fnp-3326	133	14	full	full	ADJ
fnp-3326	133	15	series	series	NOUN
fnp-3326	133	16	of	of	ADP
fnp-3326	133	17	immunostained	immunostaine	VERB
fnp-3326	133	18	coronal	coronal	ADJ
fnp-3326	133	19	sections	section	NOUN
fnp-3326	133	20	from	from	ADP
fnp-3326	133	21	10	10	NUM
fnp-3326	133	22	mice	mouse	NOUN
fnp-3326	133	23	per	per	ADP
fnp-3326	133	24	treatment	treatment	NOUN
fnp-3326	133	25	group	group	NOUN
fnp-3326	133	26	(	(	PUNCT
fnp-3326	133	27	i.e.	i.e.	X
fnp-3326	133	28	,	,	PUNCT
fnp-3326	133	29	water	water	NOUN
fnp-3326	133	30	vs.	vs.	ADP
fnp-3326	133	31	dss	dss	NOUN
fnp-3326	133	32	-	-	PUNCT
fnp-3326	133	33	treated	treat	VERB
fnp-3326	133	34	groups	group	NOUN
fnp-3326	133	35	)	)	PUNCT
fnp-3326	133	36	on	on	ADP
fnp-3326	133	37	blind	blind	ADJ
fnp-3326	133	38	-	-	PUNCT
fnp-3326	133	39	coded	code	VERB
fnp-3326	133	40	slides	slide	NOUN
fnp-3326	133	41	using	use	VERB
fnp-3326	133	42	a	a	DET
fnp-3326	133	43	previously	previously	ADV
fnp-3326	133	44	described	describe	VERB
fnp-3326	133	45	method	method	NOUN
fnp-3326	133	46	[	[	X
fnp-3326	133	47	46	46	NUM
fnp-3326	133	48	]	]	PUNCT
fnp-3326	133	49	.	.	PUNCT
fnp-3326	134	1	we	we	PRON
fnp-3326	134	2	visualized	visualize	VERB
fnp-3326	134	3	pathology	pathology	NOUN
fnp-3326	134	4	from	from	ADP
fnp-3326	134	5	one	one	NUM
fnp-3326	134	6	hemisphere	hemisphere	ADV
fnp-3326	134	7	of	of	ADP
fnp-3326	134	8	all	all	DET
fnp-3326	134	9	brain	brain	NOUN
fnp-3326	134	10	sections	section	NOUN
fnp-3326	134	11	(	(	PUNCT
fnp-3326	134	12	apart	apart	ADV
fnp-3326	134	13	from	from	ADP
fnp-3326	134	14	the	the	DET
fnp-3326	134	15	olfactory	olfactory	NOUN
fnp-3326	134	16	area	area	NOUN
fnp-3326	134	17	)	)	PUNCT
fnp-3326	134	18	using	use	VERB
fnp-3326	134	19	a	a	DET
fnp-3326	134	20	nikon	nikon	ADJ
fnp-3326	134	21	eclipse	eclipse	NOUN
fnp-3326	134	22	ni	ni	PROPN
fnp-3326	134	23	-	-	PUNCT
fnp-3326	134	24	u	u	NOUN
fnp-3326	134	25	microscope	microscope	NOUN
fnp-3326	134	26	and	and	CCONJ
fnp-3326	134	27	assigned	assign	VERB
fnp-3326	134	28	scores	score	NOUN
fnp-3326	134	29	ranging	range	VERB
fnp-3326	134	30	from	from	ADP
fnp-3326	134	31	0	0	NUM
fnp-3326	134	32	to	to	ADP
fnp-3326	134	33	4	4	NUM
fnp-3326	134	34	to	to	ADP
fnp-3326	134	35	each	each	DET
fnp-3326	134	36	brain	brain	NOUN
fnp-3326	134	37	area	area	NOUN
fnp-3326	134	38	based	base	VERB
fnp-3326	134	39	on	on	ADP
fnp-3326	134	40	the	the	DET
fnp-3326	134	41	relative	relative	ADJ
fnp-3326	134	42	abundance	abundance	NOUN
fnp-3326	134	43	of	of	ADP
fnp-3326	134	44	proteinase	proteinase	PROPN
fnp-3326	134	45	k	k	PROPN
fnp-3326	134	46	(	(	PUNCT
fnp-3326	134	47	pk)-resistant	pk)-resistant	ADJ
fnp-3326	134	48	pser129	pser129	ADJ
fnp-3326	134	49	-	-	ADJ
fnp-3326	134	50	positive	positive	ADJ
fnp-3326	134	51	inclusions	inclusion	NOUN
fnp-3326	134	52	(	(	PUNCT
fnp-3326	134	53	i.e.	i.e.	X
fnp-3326	134	54	,	,	PUNCT
fnp-3326	134	55	cell	cell	NOUN
fnp-3326	134	56	bodies	body	NOUN
fnp-3326	134	57	and	and	CCONJ
fnp-3326	134	58	neurites	neurite	NOUN
fnp-3326	134	59	)	)	PUNCT
fnp-3326	134	60	.	.	PUNCT
fnp-3326	135	1	in	in	ADP
fnp-3326	135	2	this	this	DET
fnp-3326	135	3	case	case	NOUN
fnp-3326	135	4	,	,	PUNCT
fnp-3326	135	5	0	0	NUM
fnp-3326	135	6	=	=	SYM
fnp-3326	135	7	no	no	DET
fnp-3326	135	8	aggregates	aggregate	NOUN
fnp-3326	135	9	,	,	PUNCT
fnp-3326	135	10	1	1	NUM
fnp-3326	135	11	=	=	SYM
fnp-3326	135	12	sparse	sparse	ADJ
fnp-3326	135	13	,	,	PUNCT
fnp-3326	135	14	2	2	NUM
fnp-3326	135	15	=	=	NOUN
fnp-3326	135	16	mild	mild	ADJ
fnp-3326	135	17	,	,	PUNCT
fnp-3326	135	18	3=	3=	NUM
fnp-3326	135	19	dense	dense	ADJ
fnp-3326	135	20	,	,	PUNCT
fnp-3326	135	21	4	4	NUM
fnp-3326	135	22	=	=	SYM
fnp-3326	135	23	very	very	ADV
fnp-3326	135	24	dense	dense	ADJ
fnp-3326	135	25	.	.	PUNCT
fnp-3326	136	1	for	for	ADP
fnp-3326	136	2	the	the	DET
fnp-3326	136	3	heatmap	heatmap	NOUN
fnp-3326	136	4	,	,	PUNCT
fnp-3326	136	5	we	we	PRON
fnp-3326	136	6	obtained	obtain	VERB
fnp-3326	136	7	the	the	DET
fnp-3326	136	8	average	average	ADJ
fnp-3326	136	9	score	score	NOUN
fnp-3326	136	10	values	value	NOUN
fnp-3326	136	11	of	of	ADP
fnp-3326	136	12	each	each	DET
fnp-3326	136	13	brain	brain	NOUN
fnp-3326	136	14	area	area	NOUN
fnp-3326	136	15	for	for	ADP
fnp-3326	136	16	each	each	DET
fnp-3326	136	17	treatment	treatment	NOUN
fnp-3326	136	18	group	group	NOUN
fnp-3326	136	19	.	.	PUNCT
fnp-3326	137	1	the	the	DET
fnp-3326	137	2	average	average	ADJ
fnp-3326	137	3	data	datum	NOUN
fnp-3326	137	4	for	for	ADP
fnp-3326	137	5	each	each	DET
fnp-3326	137	6	treatment	treatment	NOUN
fnp-3326	137	7	group	group	NOUN
fnp-3326	137	8	(	(	PUNCT
fnp-3326	137	9	n=10	n=10	NOUN
fnp-3326	137	10	mice	mice	NOUN
fnp-3326	137	11	/	/	SYM
fnp-3326	137	12	group	group	NOUN
fnp-3326	137	13	)	)	PUNCT
fnp-3326	137	14	was	be	AUX
fnp-3326	137	15	then	then	ADV
fnp-3326	137	16	represented	represent	VERB
fnp-3326	137	17	as	as	ADP
fnp-3326	137	18	a	a	DET
fnp-3326	137	19	heatmap	heatmap	NOUN
fnp-3326	137	20	in	in	ADP
fnp-3326	137	21	a	a	DET
fnp-3326	137	22	sagittal	sagittal	ADJ
fnp-3326	137	23	mouse	mouse	NOUN
fnp-3326	137	24	brain	brain	NOUN
fnp-3326	137	25	background	background	NOUN
fnp-3326	137	26	.	.	PUNCT
fnp-3326	138	1	to	to	PART
fnp-3326	138	2	create	create	VERB
fnp-3326	138	3	the	the	DET
fnp-3326	138	4	brain	brain	NOUN
fnp-3326	138	5	heatmap	heatmap	NOUN
fnp-3326	138	6	a	a	DET
fnp-3326	138	7	postscript	postscript	PROPN
fnp-3326	138	8	file	file	NOUN
fnp-3326	138	9	downloaded	download	VERB
fnp-3326	138	10	freely	freely	ADV
fnp-3326	138	11	from	from	ADP
fnp-3326	138	12	allen	allen	PROPN
fnp-3326	138	13	brain	brain	PROPN
fnp-3326	138	14	atlas	atlas	PROPN
fnp-3326	138	15	(	(	PUNCT
fnp-3326	138	16	mouse	mouse	PROPN
fnp-3326	138	17	,	,	PUNCT
fnp-3326	138	18	p56	p56	ADJ
fnp-3326	138	19	,	,	PUNCT
fnp-3326	138	20	sagittal	sagittal	ADJ
fnp-3326	138	21	,	,	PUNCT
fnp-3326	138	22	image	image	NOUN
fnp-3326	138	23	15	15	NUM
fnp-3326	138	24	of	of	ADP
fnp-3326	138	25	21	21	NUM
fnp-3326	138	26	;	;	PUNCT
fnp-3326	138	27	-	-	PUNCT
fnp-3326	138	28	>	>	X
fnp-3326	138	29	weblink	weblink	NOUN
fnp-3326	138	30	*	*	PUNCT
fnp-3326	138	31	)	)	PUNCT
fnp-3326	138	32	was	be	AUX
fnp-3326	138	33	converted	convert	VERB
fnp-3326	138	34	to	to	ADP
fnp-3326	138	35	an	an	DET
fnp-3326	138	36	xml	xml	NOUN
fnp-3326	138	37	in	in	ADP
fnp-3326	138	38	r	r	NOUN
fnp-3326	138	39	v	v	NUM
fnp-3326	138	40	3.4.4	3.4.4	NUM
fnp-3326	138	41	,	,	PUNCT
fnp-3326	138	42	and	and	CCONJ
fnp-3326	138	43	the	the	DET
fnp-3326	138	44	mean	mean	ADJ
fnp-3326	138	45	scores	score	NOUN
fnp-3326	138	46	were	be	AUX
fnp-3326	138	47	manually	manually	ADV
fnp-3326	138	48	assigned	assign	VERB
fnp-3326	138	49	to	to	ADP
fnp-3326	138	50	respective	respective	ADJ
fnp-3326	138	51	brain	brain	NOUN
fnp-3326	138	52	regions	region	NOUN
fnp-3326	138	53	.	.	PUNCT
fnp-3326	139	1	the	the	DET
fnp-3326	139	2	remaining	remain	VERB
fnp-3326	139	3	brain	brain	NOUN
fnp-3326	139	4	regions	region	NOUN
fnp-3326	139	5	were	be	AUX
fnp-3326	139	6	estimated	estimate	VERB
fnp-3326	139	7	via	via	ADP
fnp-3326	139	8	the	the	DET
fnp-3326	139	9	r	r	NOUN
fnp-3326	139	10	package	package	NOUN
fnp-3326	139	11	‘	'	PUNCT
fnp-3326	139	12	akima	akima	NOUN
fnp-3326	139	13	’	'	PUNCT
fnp-3326	139	14	,	,	PUNCT
fnp-3326	139	15	using	use	VERB
fnp-3326	139	16	a	a	DET
fnp-3326	139	17	pointwise	pointwise	ADJ
fnp-3326	139	18	bivariate	bivariate	ADJ
fnp-3326	139	19	interpolation	interpolation	NOUN
fnp-3326	139	20	algorithm	algorithm	NOUN
fnp-3326	139	21	for	for	ADP
fnp-3326	139	22	irregular	irregular	ADJ
fnp-3326	139	23	data	datum	NOUN
fnp-3326	139	24	on	on	ADP
fnp-3326	139	25	the	the	DET
fnp-3326	139	26	mean	mean	NOUN
fnp-3326	139	27	x	x	X
fnp-3326	139	28	and	and	CCONJ
fnp-3326	139	29	y	y	PROPN
fnp-3326	139	30	coordinates	coordinate	NOUN
fnp-3326	139	31	for	for	ADP
fnp-3326	139	32	each	each	DET
fnp-3326	139	33	brain	brain	NOUN
fnp-3326	139	34	region	region	NOUN
fnp-3326	139	35	.	.	PUNCT
fnp-3326	139	36	  	  	SPACE
fnp-3326	140	1	*	*	PUNCT
fnp-3326	140	2	(	(	PUNCT
fnp-3326	140	3	http://atlas.brain-map.org/atlas?atlas=2#atlas=2&structure=771&resolution=16.75&x=%7755.7470703125&y=3899.625&zoom=-3&plate=100883867&z=5	http://atlas.brain-map.org/atlas?atlas=2#atlas=2&structure=771&resolution=16.75&x=%7755.7470703125&y=3899.625&zoom=-3&plate=100883867&z=5	NOUN
fnp-3326	140	4	)	)	PUNCT
fnp-3326	140	5	densitometry	densitometry	NOUN
fnp-3326	140	6	of	of	ADP
fnp-3326	140	7	pser129	pser129	PROPN
fnp-3326	140	8	αsyn	αsyn	ADJ
fnp-3326	140	9	brain	brain	NOUN
fnp-3326	140	10	pathology	pathology	NOUN
fnp-3326	140	11	the	the	DET
fnp-3326	140	12	density	density	NOUN
fnp-3326	140	13	of	of	ADP
fnp-3326	140	14	pser129	pser129	PROPN
fnp-3326	140	15	pathology	pathology	NOUN
fnp-3326	140	16	in	in	ADP
fnp-3326	140	17	12	12	NUM
fnp-3326	140	18	major	major	ADJ
fnp-3326	140	19	brain	brain	NOUN
fnp-3326	140	20	areas	area	NOUN
fnp-3326	140	21	(	(	PUNCT
fnp-3326	140	22	reticular	reticular	ADJ
fnp-3326	140	23	nucleus	nucleus	NOUN
fnp-3326	140	24	,	,	PUNCT
fnp-3326	140	25	pontine	pontine	ADJ
fnp-3326	140	26	reticular	reticular	ADJ
fnp-3326	140	27	nucleus	nucleus	NOUN
fnp-3326	140	28	,	,	PUNCT
fnp-3326	140	29	periaqueductal	periaqueductal	ADJ
fnp-3326	140	30	gray	gray	NOUN
fnp-3326	140	31	,	,	PUNCT
fnp-3326	140	32	gray	gray	ADJ
fnp-3326	140	33	and	and	CCONJ
fnp-3326	140	34	white	white	ADJ
fnp-3326	140	35	layer	layer	NOUN
fnp-3326	140	36	,	,	PUNCT
fnp-3326	140	37	reticular	reticular	ADJ
fnp-3326	140	38	formation	formation	NOUN
fnp-3326	140	39	,	,	PUNCT
fnp-3326	140	40	substantia	substantia	NOUN
fnp-3326	140	41	nigra	nigra	NOUN
fnp-3326	140	42	,	,	PUNCT
fnp-3326	140	43	ventral	ventral	ADJ
fnp-3326	140	44	tegmental	tegmental	ADJ
fnp-3326	140	45	area	area	NOUN
fnp-3326	140	46	,	,	PUNCT
fnp-3326	140	47	thalamus	thalamus	NOUN
fnp-3326	140	48	,	,	PUNCT
fnp-3326	140	49	hypothalamus	hypothalamus	PROPN
fnp-3326	140	50	,	,	PUNCT
fnp-3326	140	51	central	central	ADJ
fnp-3326	140	52	amygdala	amygdala	NOUN
fnp-3326	140	53	,	,	PUNCT
fnp-3326	140	54	pallidum	pallidum	NOUN
fnp-3326	140	55	and	and	CCONJ
fnp-3326	140	56	striatum	striatum	NOUN
fnp-3326	140	57	)	)	PUNCT
fnp-3326	140	58	was	be	AUX
fnp-3326	140	59	determined	determine	VERB
fnp-3326	140	60	in	in	ADP
fnp-3326	140	61	the	the	DET
fnp-3326	140	62	water	water	NOUN
fnp-3326	140	63	and	and	CCONJ
fnp-3326	140	64	dss	dss	NOUN
fnp-3326	140	65	-	-	PUNCT
fnp-3326	140	66	treated	treat	VERB
fnp-3326	140	67	animals	animal	NOUN
fnp-3326	140	68	.	.	PUNCT
fnp-3326	141	1	a	a	DET
fnp-3326	141	2	nikon	nikon	PROPN
fnp-3326	141	3	eclipse	eclipse	NOUN
fnp-3326	141	4	ni	ni	PROPN
fnp-3326	141	5	-	-	PUNCT
fnp-3326	141	6	u	u	NOUN
fnp-3326	141	7	microscope	microscope	NOUN
fnp-3326	141	8	was	be	AUX
fnp-3326	141	9	used	use	VERB
fnp-3326	141	10	to	to	PART
fnp-3326	141	11	acquire	acquire	VERB
fnp-3326	141	12	20x	20x	NOUN
fnp-3326	141	13	magnification	magnification	NOUN
fnp-3326	141	14	images	image	NOUN
fnp-3326	141	15	(	(	PUNCT
fnp-3326	141	16	without	without	ADP
fnp-3326	141	17	condenser	condenser	PROPN
fnp-3326	141	18	lens	lens	PROPN
fnp-3326	141	19	)	)	PUNCT
fnp-3326	141	20	from	from	ADP
fnp-3326	141	21	all	all	DET
fnp-3326	141	22	the	the	DET
fnp-3326	141	23	indicated	indicate	VERB
fnp-3326	141	24	brain	brain	NOUN
fnp-3326	141	25	areas	area	NOUN
fnp-3326	141	26	,	,	PUNCT
fnp-3326	141	27	using	use	VERB
fnp-3326	141	28	the	the	DET
fnp-3326	141	29	same	same	ADJ
fnp-3326	141	30	exposure	exposure	NOUN
fnp-3326	141	31	time	time	NOUN
fnp-3326	141	32	for	for	ADP
fnp-3326	141	33	all	all	DET
fnp-3326	141	34	images	image	NOUN
fnp-3326	141	35	.	.	PUNCT
fnp-3326	142	1	in	in	ADP
fnp-3326	142	2	all	all	DET
fnp-3326	142	3	cases	case	NOUN
fnp-3326	142	4	,	,	PUNCT
fnp-3326	142	5	images	image	NOUN
fnp-3326	142	6	were	be	AUX
fnp-3326	142	7	acquired	acquire	VERB
fnp-3326	142	8	on	on	ADP
fnp-3326	142	9	three	three	NUM
fnp-3326	142	10	sections	section	NOUN
fnp-3326	142	11	separated	separate	VERB
fnp-3326	142	12	by	by	ADP
fnp-3326	142	13	420	420	NUM
fnp-3326	142	14	μm	μm	NOUN
fnp-3326	142	15	intervals	interval	NOUN
fnp-3326	142	16	(	(	PUNCT
fnp-3326	142	17	localized	localize	VERB
fnp-3326	142	18	between	between	ADP
fnp-3326	142	19	bregma	bregma	NOUN
fnp-3326	142	20	)	)	PUNCT
fnp-3326	142	21	.	.	PUNCT
fnp-3326	143	1	we	we	PRON
fnp-3326	143	2	then	then	ADV
fnp-3326	143	3	processed	process	VERB
fnp-3326	143	4	the	the	DET
fnp-3326	143	5	acquired	acquire	VERB
fnp-3326	143	6	images	image	NOUN
fnp-3326	143	7	using	use	VERB
fnp-3326	143	8	image	image	NOUN
fnp-3326	143	9	j64	j64	NOUN
fnp-3326	144	1	[	[	X
fnp-3326	144	2	47	47	NUM
fnp-3326	144	3	]	]	PUNCT
fnp-3326	144	4	,	,	PUNCT
fnp-3326	144	5	created	create	VERB
fnp-3326	144	6	a	a	DET
fnp-3326	144	7	mask	mask	NOUN
fnp-3326	144	8	(	(	PUNCT
fnp-3326	144	9	to	to	PART
fnp-3326	144	10	exclude	exclude	VERB
fnp-3326	144	11	background	background	NOUN
fnp-3326	144	12	)	)	PUNCT
fnp-3326	144	13	that	that	PRON
fnp-3326	144	14	redirects	redirect	VERB
fnp-3326	144	15	to	to	ADP
fnp-3326	144	16	the	the	DET
fnp-3326	144	17	original	original	ADJ
fnp-3326	144	18	image	image	NOUN
fnp-3326	144	19	for	for	ADP
fnp-3326	144	20	analysis	analysis	NOUN
fnp-3326	144	21	,	,	PUNCT
fnp-3326	144	22	measured	measure	VERB
fnp-3326	144	23	the	the	DET
fnp-3326	144	24	total	total	ADJ
fnp-3326	144	25	area	area	NOUN
fnp-3326	144	26	and	and	CCONJ
fnp-3326	144	27	the	the	DET
fnp-3326	144	28	mean	mean	ADJ
fnp-3326	144	29	grey	grey	ADJ
fnp-3326	144	30	value	value	NOUN
fnp-3326	144	31	of	of	ADP
fnp-3326	144	32	the	the	DET
fnp-3326	144	33	area	area	NOUN
fnp-3326	144	34	that	that	PRON
fnp-3326	144	35	had	have	VERB
fnp-3326	144	36	inclusions	inclusion	NOUN
fnp-3326	144	37	.	.	PUNCT
fnp-3326	145	1	for	for	ADP
fnp-3326	145	2	brain	brain	NOUN
fnp-3326	145	3	areas	area	NOUN
fnp-3326	145	4	such	such	ADJ
fnp-3326	145	5	as	as	ADP
fnp-3326	145	6	periaqueductal	periaqueductal	ADJ
fnp-3326	145	7	gray	gray	NOUN
fnp-3326	145	8	that	that	PRON
fnp-3326	145	9	do	do	AUX
fnp-3326	145	10	not	not	PART
fnp-3326	145	11	fill	fill	VERB
fnp-3326	145	12	the	the	DET
fnp-3326	145	13	entirety	entirety	NOUN
fnp-3326	145	14	of	of	ADP
fnp-3326	145	15	the	the	DET
fnp-3326	145	16	field	field	NOUN
fnp-3326	145	17	to	to	PART
fnp-3326	145	18	be	be	AUX
fnp-3326	145	19	analyzed	analyze	VERB
fnp-3326	145	20	,	,	PUNCT
fnp-3326	145	21	we	we	PRON
fnp-3326	145	22	drew	draw	VERB
fnp-3326	145	23	a	a	DET
fnp-3326	145	24	contour	contour	NOUN
fnp-3326	145	25	of	of	ADP
fnp-3326	145	26	the	the	DET
fnp-3326	145	27	area	area	NOUN
fnp-3326	145	28	and	and	CCONJ
fnp-3326	145	29	the	the	DET
fnp-3326	145	30	analysis	analysis	NOUN
fnp-3326	145	31	was	be	AUX
fnp-3326	145	32	performed	perform	VERB
fnp-3326	145	33	only	only	ADV
fnp-3326	145	34	within	within	ADP
fnp-3326	145	35	that	that	DET
fnp-3326	145	36	contoured	contoured	ADJ
fnp-3326	145	37	area	area	NOUN
fnp-3326	145	38	.	.	PUNCT
fnp-3326	146	1	we	we	PRON
fnp-3326	146	2	subsequently	subsequently	ADV
fnp-3326	146	3	calculated	calculate	VERB
fnp-3326	146	4	the	the	DET
fnp-3326	146	5	grey	grey	ADJ
fnp-3326	146	6	value	value	NOUN
fnp-3326	146	7	of	of	ADP
fnp-3326	146	8	the	the	DET
fnp-3326	146	9	area	area	NOUN
fnp-3326	146	10	per	per	ADP
fnp-3326	146	11	square	square	ADJ
fnp-3326	146	12	pixels	pixel	NOUN
fnp-3326	146	13	for	for	ADP
fnp-3326	146	14	each	each	DET
fnp-3326	146	15	image	image	NOUN
fnp-3326	146	16	(	(	PUNCT
fnp-3326	146	17	i.e.	i.e.	X
fnp-3326	146	18	,	,	PUNCT
fnp-3326	146	19	a.u./px2	a.u./px2	PUNCT
fnp-3326	146	20	=	=	SYM
fnp-3326	146	21	mean	mean	ADJ
fnp-3326	146	22	grey	grey	NOUN
fnp-3326	146	23	value	value	NOUN
fnp-3326	146	24	x	x	X
fnp-3326	146	25	area	area	NOUN
fnp-3326	146	26	stained	stain	VERB
fnp-3326	146	27	/	/	SYM
fnp-3326	146	28	total	total	NOUN
fnp-3326	146	29	area	area	NOUN
fnp-3326	146	30	assessed	assess	VERB
fnp-3326	146	31	)	)	PUNCT
fnp-3326	146	32	.	.	PUNCT
fnp-3326	147	1	based	base	VERB
fnp-3326	147	2	on	on	ADP
fnp-3326	147	3	this	this	PRON
fnp-3326	147	4	,	,	PUNCT
fnp-3326	147	5	we	we	PRON
fnp-3326	147	6	calculated	calculate	VERB
fnp-3326	147	7	the	the	DET
fnp-3326	147	8	average	average	ADJ
fnp-3326	147	9	grey	grey	ADJ
fnp-3326	147	10	value	value	NOUN
fnp-3326	147	11	per	per	ADP
fnp-3326	147	12	square	square	ADJ
fnp-3326	147	13	pixels	pixel	NOUN
fnp-3326	147	14	for	for	ADP
fnp-3326	147	15	each	each	DET
fnp-3326	147	16	brain	brain	NOUN
fnp-3326	147	17	area	area	NOUN
fnp-3326	147	18	for	for	ADP
fnp-3326	147	19	each	each	DET
fnp-3326	147	20	animal	animal	NOUN
fnp-3326	147	21	(	(	PUNCT
fnp-3326	147	22	n	n	NOUN
fnp-3326	147	23	=	=	SYM
fnp-3326	147	24	6	6	NUM
fnp-3326	147	25	mice	mouse	NOUN
fnp-3326	147	26	/	/	SYM
fnp-3326	147	27	group	group	NOUN
fnp-3326	147	28	)	)	PUNCT
fnp-3326	147	29	,	,	PUNCT
fnp-3326	147	30	and	and	CCONJ
fnp-3326	147	31	then	then	ADV
fnp-3326	147	32	extended	extend	VERB
fnp-3326	147	33	this	this	DET
fnp-3326	147	34	calculation	calculation	NOUN
fnp-3326	147	35	to	to	PART
fnp-3326	147	36	determine	determine	VERB
fnp-3326	147	37	the	the	DET
fnp-3326	147	38	average	average	ADJ
fnp-3326	147	39	grey	grey	ADJ
fnp-3326	147	40	value	value	NOUN
fnp-3326	147	41	per	per	ADP
fnp-3326	147	42	square	square	ADJ
fnp-3326	147	43	pixels	pixel	NOUN
fnp-3326	147	44	for	for	ADP
fnp-3326	147	45	each	each	DET
fnp-3326	147	46	treatment	treatment	NOUN
fnp-3326	147	47	group	group	NOUN
fnp-3326	147	48	and	and	CCONJ
fnp-3326	147	49	each	each	PRON
fnp-3326	147	50	of	of	ADP
fnp-3326	147	51	the	the	DET
fnp-3326	147	52	twelve	twelve	NUM
fnp-3326	147	53	brain	brain	NOUN
fnp-3326	147	54	areas	area	NOUN
fnp-3326	147	55	of	of	ADP
fnp-3326	147	56	interest	interest	NOUN
fnp-3326	147	57	.	.	PUNCT
fnp-3326	148	1	blinding	blind	VERB
fnp-3326	148	2	of	of	ADP
fnp-3326	148	3	experimenters	experimenter	NOUN
fnp-3326	148	4	for	for	ADP
fnp-3326	148	5	histological	histological	ADJ
fnp-3326	148	6	and	and	CCONJ
fnp-3326	148	7	immunohistochemical	immunohistochemical	ADJ
fnp-3326	148	8	analyses	analysis	NOUN
fnp-3326	148	9	for	for	ADP
fnp-3326	148	10	analyses	analysis	NOUN
fnp-3326	148	11	of	of	ADP
fnp-3326	148	12	colon	colon	NOUN
fnp-3326	148	13	and	and	CCONJ
fnp-3326	148	14	brain	brain	NOUN
fnp-3326	148	15	tissue	tissue	NOUN
fnp-3326	148	16	on	on	ADP
fnp-3326	148	17	slides	slide	NOUN
fnp-3326	148	18	,	,	PUNCT
fnp-3326	148	19	a	a	DET
fnp-3326	148	20	second	second	ADJ
fnp-3326	148	21	individual	individual	ADJ
fnp-3326	148	22	assigned	assign	VERB
fnp-3326	148	23	unique	unique	ADJ
fnp-3326	148	24	codes	code	NOUN
fnp-3326	148	25	to	to	ADP
fnp-3326	148	26	stained	stain	VERB
fnp-3326	148	27	slides	slide	NOUN
fnp-3326	148	28	.	.	PUNCT
fnp-3326	149	1	therefore	therefore	ADV
fnp-3326	149	2	,	,	PUNCT
fnp-3326	149	3	the	the	DET
fnp-3326	149	4	experimenter	experimenter	NOUN
fnp-3326	149	5	conducted	conduct	VERB
fnp-3326	149	6	the	the	DET
fnp-3326	149	7	analyses	analysis	NOUN
fnp-3326	149	8	blinded	blind	VERB
fnp-3326	149	9	to	to	ADP
fnp-3326	149	10	the	the	DET
fnp-3326	149	11	identity	identity	NOUN
fnp-3326	149	12	of	of	ADP
fnp-3326	149	13	the	the	DET
fnp-3326	149	14	mice	mouse	NOUN
fnp-3326	149	15	.	.	PUNCT
fnp-3326	150	1	for	for	ADP
fnp-3326	150	2	randomization	randomization	NOUN
fnp-3326	150	3	of	of	ADP
fnp-3326	150	4	treatment	treatment	NOUN
fnp-3326	150	5	groups	group	NOUN
fnp-3326	150	6	see	see	VERB
fnp-3326	150	7	above	above	ADV
fnp-3326	150	8	.	.	PUNCT
fnp-3326	151	1	mrna	mrna	PROPN
fnp-3326	151	2	expression	expression	NOUN
fnp-3326	151	3	to	to	PART
fnp-3326	151	4	assess	assess	VERB
fnp-3326	151	5	mrna	mrna	NOUN
fnp-3326	151	6	expression	expression	NOUN
fnp-3326	151	7	levels	level	NOUN
fnp-3326	151	8	from	from	ADP
fnp-3326	151	9	the	the	DET
fnp-3326	151	10	proximal	proximal	ADJ
fnp-3326	151	11	colon	colon	NOUN
fnp-3326	151	12	,	,	PUNCT
fnp-3326	151	13	rna	rna	PROPN
fnp-3326	151	14	was	be	AUX
fnp-3326	151	15	extracted	extract	VERB
fnp-3326	151	16	from	from	ADP
fnp-3326	151	17	fresh	fresh	ADJ
fnp-3326	151	18	frozen	frozen	ADJ
fnp-3326	151	19	tissue	tissue	NOUN
fnp-3326	151	20	with	with	ADP
fnp-3326	151	21	magnalyser	magnalyser	PROPN
fnp-3326	151	22	green	green	ADJ
fnp-3326	151	23	beads	bead	NOUN
fnp-3326	151	24	(	(	PUNCT
fnp-3326	151	25	roche	roche	NOUN
fnp-3326	151	26	diagnostics	diagnostic	NOUN
fnp-3326	151	27	,	,	PUNCT
fnp-3326	151	28	mannheim	mannheim	PROPN
fnp-3326	151	29	,	,	PUNCT
fnp-3326	151	30	germany	germany	PROPN
fnp-3326	151	31	)	)	PUNCT
fnp-3326	151	32	and	and	CCONJ
fnp-3326	151	33	qiazol	qiazol	ADJ
fnp-3326	151	34	lysis	lysis	NOUN
fnp-3326	151	35	(	(	PUNCT
fnp-3326	151	36	reagent	reagent	ADJ
fnp-3326	151	37	cat.no.79306	cat.no.79306	NOUN
fnp-3326	151	38	,	,	PUNCT
fnp-3326	151	39	hilden	hilden	PROPN
fnp-3326	151	40	,	,	PUNCT
fnp-3326	151	41	germany	germany	PROPN
fnp-3326	151	42	)	)	PUNCT
fnp-3326	151	43	purified	purify	VERB
fnp-3326	151	44	on	on	ADP
fnp-3326	151	45	magnapure	magnapure	ADJ
fnp-3326	151	46	lc	lc	PROPN
fnp-3326	151	47	(	(	PUNCT
fnp-3326	151	48	hp	hp	PROPN
fnp-3326	151	49	kit	kit	NOUN
fnp-3326	151	50	no.03542394001	no.03542394001	PROPN
fnp-3326	151	51	,	,	PUNCT
fnp-3326	151	52	f.	f.	PROPN
fnp-3326	151	53	hoffmann	hoffmann	PROPN
fnp-3326	151	54	-	-	PUNCT
fnp-3326	151	55	la	la	PROPN
fnp-3326	151	56	roche	roche	PROPN
fnp-3326	151	57	ag	ag	PROPN
fnp-3326	151	58	,	,	PUNCT
fnp-3326	151	59	rotkreuz	rotkreuz	PROPN
fnp-3326	151	60	,	,	PUNCT
fnp-3326	151	61	switzerland	switzerland	PROPN
fnp-3326	151	62	)	)	PUNCT
fnp-3326	151	63	and	and	CCONJ
fnp-3326	151	64	amplified	amplify	VERB
fnp-3326	151	65	via	via	ADP
fnp-3326	151	66	real	real	ADJ
fnp-3326	151	67	-	-	PUNCT
fnp-3326	151	68	time	time	NOUN
fnp-3326	151	69	pcr	pcr	NOUN
fnp-3326	151	70	(	(	PUNCT
fnp-3326	151	71	4	4	NUM
fnp-3326	151	72	ng	ng	PROPN
fnp-3326	151	73	rna	rna	PROPN
fnp-3326	151	74	/	/	SYM
fnp-3326	151	75	reaction	reaction	NOUN
fnp-3326	151	76	;	;	PUNCT
fnp-3326	151	77	lightcycler	lightcycler	NOUN
fnp-3326	151	78	480	480	NUM
fnp-3326	151	79	,	,	PUNCT
fnp-3326	151	80	roche	roche	NOUN
fnp-3326	151	81	diagnostics	diagnostic	NOUN
fnp-3326	151	82	corporation	corporation	NOUN
fnp-3326	151	83	,	,	PUNCT
fnp-3326	151	84	indianapolis	indianapolis	PROPN
fnp-3326	151	85	,	,	PUNCT
fnp-3326	151	86	usa	usa	PROPN
fnp-3326	151	87	)	)	PUNCT
fnp-3326	151	88	.	.	PUNCT
fnp-3326	152	1	amplification	amplification	NOUN
fnp-3326	152	2	of	of	ADP
fnp-3326	152	3	mrna	mrna	PROPN
fnp-3326	152	4	was	be	AUX
fnp-3326	152	5	performed	perform	VERB
fnp-3326	152	6	by	by	ADP
fnp-3326	152	7	using	use	VERB
fnp-3326	152	8	taqman	taqman	NOUN
fnp-3326	152	9	probes	probe	NOUN
fnp-3326	152	10	for	for	ADP
fnp-3326	152	11	human	human	ADJ
fnp-3326	152	12	or	or	CCONJ
fnp-3326	152	13	murine	murine	ADJ
fnp-3326	152	14	specific	specific	ADJ
fnp-3326	152	15	α	α	NOUN
fnp-3326	152	16	-	-	PUNCT
fnp-3326	152	17	synuclein	synuclein	NOUN
fnp-3326	152	18	and	and	CCONJ
fnp-3326	152	19	for	for	ADP
fnp-3326	152	20	selected	select	VERB
fnp-3326	152	21	cytokines	cytokine	NOUN
fnp-3326	152	22	/	/	SYM
fnp-3326	152	23	chemokines	chemokine	NOUN
fnp-3326	152	24	(	(	PUNCT
fnp-3326	152	25	applied	apply	VERB
fnp-3326	152	26	biosystems	biosystems	PROPN
fnp-3326	152	27	europe	europe	PROPN
fnp-3326	152	28	b.v	b.v	PROPN
fnp-3326	152	29	.	.	PROPN
fnp-3326	152	30	,	,	PUNCT
fnp-3326	152	31	zug	zug	PROPN
fnp-3326	152	32	,	,	PUNCT
fnp-3326	152	33	switzerland	switzerland	PROPN
fnp-3326	152	34	)	)	PUNCT
fnp-3326	152	35	.	.	PUNCT
fnp-3326	153	1	target	target	PROPN
fnp-3326	153	2	mrna	mrna	PROPN
fnp-3326	153	3	was	be	AUX
fnp-3326	153	4	normalized	normalize	VERB
fnp-3326	153	5	to	to	PART
fnp-3326	153	6	tissue	tissue	VERB
fnp-3326	153	7	specific	specific	ADJ
fnp-3326	153	8	murine	murine	ADJ
fnp-3326	153	9	gapdh	gapdh	NOUN
fnp-3326	153	10	levels	level	NOUN
fnp-3326	153	11	and	and	CCONJ
fnp-3326	153	12	displayed	display	VERB
fnp-3326	153	13	as	as	ADP
fnp-3326	153	14	relative	relative	ADJ
fnp-3326	153	15	expression	expression	NOUN
fnp-3326	153	16	after	after	ADP
fnp-3326	153	17	30	30	NUM
fnp-3326	153	18	amplification	amplification	NOUN
fnp-3326	153	19	cycles	cycle	NOUN
fnp-3326	153	20	.	.	PUNCT
fnp-3326	154	1	statistics	statistic	NOUN
fnp-3326	154	2	measurements	measurement	NOUN
fnp-3326	154	3	for	for	ADP
fnp-3326	154	4	inflammation	inflammation	NOUN
fnp-3326	154	5	and	and	CCONJ
fnp-3326	154	6	αsyn	αsyn	ADJ
fnp-3326	154	7	accumulation	accumulation	NOUN
fnp-3326	154	8	in	in	ADP
fnp-3326	154	9	the	the	DET
fnp-3326	154	10	ens	en	NOUN
fnp-3326	154	11	were	be	AUX
fnp-3326	154	12	taken	take	VERB
fnp-3326	154	13	from	from	ADP
fnp-3326	154	14	distinct	distinct	ADJ
fnp-3326	154	15	samples	sample	NOUN
fnp-3326	154	16	(	(	PUNCT
fnp-3326	154	17	e.g.	e.g.	ADV
fnp-3326	154	18	,	,	PUNCT
fnp-3326	154	19	in	in	ADP
fnp-3326	154	20	three	three	NUM
fnp-3326	154	21	to	to	PART
fnp-3326	154	22	six	six	NUM
fnp-3326	154	23	technical	technical	ADJ
fnp-3326	154	24	replicates	replicate	NOUN
fnp-3326	154	25	per	per	ADP
fnp-3326	154	26	mouse	mouse	NOUN
fnp-3326	154	27	)	)	PUNCT
fnp-3326	154	28	.	.	PUNCT
fnp-3326	155	1	data	datum	NOUN
fnp-3326	155	2	from	from	ADP
fnp-3326	155	3	each	each	DET
fnp-3326	155	4	mouse	mouse	NOUN
fnp-3326	155	5	was	be	AUX
fnp-3326	155	6	used	use	VERB
fnp-3326	155	7	only	only	ADV
fnp-3326	155	8	once	once	ADV
fnp-3326	155	9	,	,	PUNCT
fnp-3326	155	10	thus	thus	ADV
fnp-3326	155	11	no	no	DET
fnp-3326	155	12	repeated	repeat	VERB
fnp-3326	155	13	measure	measure	NOUN
fnp-3326	155	14	of	of	ADP
fnp-3326	155	15	the	the	DET
fnp-3326	155	16	same	same	ADJ
fnp-3326	155	17	sample	sample	NOUN
fnp-3326	155	18	was	be	AUX
fnp-3326	155	19	performed	perform	VERB
fnp-3326	155	20	.	.	PUNCT
fnp-3326	156	1	statistical	statistical	ADJ
fnp-3326	156	2	analysis	analysis	NOUN
fnp-3326	156	3	of	of	ADP
fnp-3326	156	4	gut	gut	NOUN
fnp-3326	156	5	pathology	pathology	NOUN
fnp-3326	156	6	and	and	CCONJ
fnp-3326	156	7	inflammation	inflammation	NOUN
fnp-3326	156	8	was	be	AUX
fnp-3326	156	9	performed	perform	VERB
fnp-3326	156	10	using	use	VERB
fnp-3326	156	11	graphpad	graphpad	NOUN
fnp-3326	156	12	prism	prism	NOUN
fnp-3326	156	13	6.04	6.04	NUM
fnp-3326	156	14	or	or	CCONJ
fnp-3326	156	15	7.0	7.0	NUM
fnp-3326	156	16	software	software	NOUN
fnp-3326	156	17	(	(	PUNCT
fnp-3326	156	18	graphpad	graphpad	NOUN
fnp-3326	156	19	software	software	PROPN
fnp-3326	156	20	,	,	PUNCT
fnp-3326	156	21	inc	inc	PROPN
fnp-3326	156	22	.	.	PROPN
fnp-3326	156	23	la	la	PROPN
fnp-3326	156	24	jolla	jolla	PROPN
fnp-3326	156	25	,	,	PUNCT
fnp-3326	156	26	ca	ca	PROPN
fnp-3326	156	27	,	,	PUNCT
fnp-3326	156	28	usa	usa	PROPN
fnp-3326	156	29	)	)	PUNCT
fnp-3326	156	30	.	.	PUNCT
fnp-3326	157	1	the	the	DET
fnp-3326	157	2	results	result	NOUN
fnp-3326	157	3	are	be	AUX
fnp-3326	157	4	expressed	express	VERB
fnp-3326	157	5	as	as	ADP
fnp-3326	157	6	mean	mean	ADJ
fnp-3326	157	7	values	value	NOUN
fnp-3326	157	8	±	±	NUM
fnp-3326	157	9	standard	standard	ADJ
fnp-3326	157	10	errors	error	NOUN
fnp-3326	157	11	of	of	ADP
fnp-3326	157	12	the	the	DET
fnp-3326	157	13	mean	mean	ADJ
fnp-3326	157	14	(	(	PUNCT
fnp-3326	157	15	s.e.m	s.e.m	NOUN
fnp-3326	157	16	.	.	PUNCT
fnp-3326	157	17	)	)	PUNCT
fnp-3326	157	18	.	.	PUNCT
fnp-3326	158	1	student	student	NOUN
fnp-3326	158	2	’s	’s	PART
fnp-3326	158	3	t	t	PROPN
fnp-3326	158	4	-	-	PUNCT
fnp-3326	158	5	test	test	NOUN
fnp-3326	158	6	(	(	PUNCT
fnp-3326	158	7	or	or	CCONJ
fnp-3326	158	8	welch	welch	PROPN
fnp-3326	158	9	’s	’s	PART
fnp-3326	158	10	t	t	PROPN
fnp-3326	158	11	-	-	PUNCT
fnp-3326	158	12	test	test	NOUN
fnp-3326	158	13	for	for	ADP
fnp-3326	158	14	unequal	unequal	ADJ
fnp-3326	158	15	variances	variance	NOUN
fnp-3326	158	16	)	)	PUNCT
fnp-3326	158	17	was	be	AUX
fnp-3326	158	18	used	use	VERB
fnp-3326	158	19	to	to	PART
fnp-3326	158	20	compare	compare	VERB
fnp-3326	158	21	two	two	NUM
fnp-3326	158	22	groups	group	NOUN
fnp-3326	158	23	and	and	CCONJ
fnp-3326	158	24	anova	anova	PROPN
fnp-3326	158	25	was	be	AUX
fnp-3326	158	26	used	use	VERB
fnp-3326	158	27	for	for	ADP
fnp-3326	158	28	multi	multi	NOUN
fnp-3326	158	29	-	-	NOUN
fnp-3326	158	30	comparison	comparison	NOUN
fnp-3326	158	31	of	of	ADP
fnp-3326	158	32	groups	group	NOUN
fnp-3326	158	33	followed	follow	VERB
fnp-3326	158	34	by	by	ADP
fnp-3326	158	35	tukey	tukey	PROPN
fnp-3326	158	36	hsd	hsd	PROPN
fnp-3326	158	37	post	post	ADJ
fnp-3326	158	38	-	-	ADJ
fnp-3326	158	39	hoc	hoc	ADJ
fnp-3326	158	40	analysis	analysis	NOUN
fnp-3326	158	41	.	.	PUNCT
fnp-3326	159	1	for	for	ADP
fnp-3326	159	2	the	the	DET
fnp-3326	159	3	statistical	statistical	ADJ
fnp-3326	159	4	analysis	analysis	NOUN
fnp-3326	159	5	of	of	ADP
fnp-3326	159	6	the	the	DET
fnp-3326	159	7	mrna	mrna	PROPN
fnp-3326	159	8	expression	expression	NOUN
fnp-3326	159	9	,	,	PUNCT
fnp-3326	159	10	data	datum	NOUN
fnp-3326	159	11	quality	quality	NOUN
fnp-3326	159	12	was	be	AUX
fnp-3326	159	13	assessed	assess	VERB
fnp-3326	159	14	by	by	ADP
fnp-3326	159	15	inspecting	inspect	VERB
fnp-3326	159	16	the	the	DET
fnp-3326	159	17	distribution	distribution	NOUN
fnp-3326	159	18	of	of	ADP
fnp-3326	159	19	cp	cp	NUM
fnp-3326	159	20	values	value	NOUN
fnp-3326	159	21	of	of	ADP
fnp-3326	159	22	reference	reference	NOUN
fnp-3326	159	23	endogenous	endogenous	ADJ
fnp-3326	159	24	genes	gene	NOUN
fnp-3326	159	25	across	across	ADP
fnp-3326	159	26	samples	sample	NOUN
fnp-3326	159	27	,	,	PUNCT
fnp-3326	159	28	by	by	ADP
fnp-3326	159	29	inspecting	inspect	VERB
fnp-3326	159	30	the	the	DET
fnp-3326	159	31	level	level	NOUN
fnp-3326	159	32	of	of	ADP
fnp-3326	159	33	cp	cp	NUM
fnp-3326	159	34	variation	variation	NOUN
fnp-3326	159	35	between	between	ADP
fnp-3326	159	36	technical	technical	ADJ
fnp-3326	159	37	replicates	replicate	NOUN
fnp-3326	159	38	and	and	CCONJ
fnp-3326	159	39	by	by	ADP
fnp-3326	159	40	exploring	explore	VERB
fnp-3326	159	41	the	the	DET
fnp-3326	159	42	samples	sample	NOUN
fnp-3326	159	43	multivariate	multivariate	NOUN
fnp-3326	159	44	signal	signal	NOUN
fnp-3326	159	45	distribution	distribution	NOUN
fnp-3326	159	46	as	as	ADP
fnp-3326	159	47	in	in	ADP
fnp-3326	159	48	a	a	DET
fnp-3326	159	49	principal	principal	ADJ
fnp-3326	159	50	component	component	NOUN
fnp-3326	159	51	analysis	analysis	NOUN
fnp-3326	159	52	.	.	PUNCT
fnp-3326	160	1	relative	relative	ADJ
fnp-3326	160	2	gene	gene	NOUN
fnp-3326	160	3	expression	expression	NOUN
fnp-3326	160	4	levels	level	NOUN
fnp-3326	160	5	were	be	AUX
fnp-3326	160	6	expressed	express	VERB
fnp-3326	160	7	as	as	ADP
fnp-3326	160	8	2-(cpgene	2-(cpgene	NUM
fnp-3326	160	9	–	–	PUNCT
fnp-3326	160	10	cpref	cpref	NOUN
fnp-3326	160	11	)	)	PUNCT
fnp-3326	160	12	.	.	PUNCT
fnp-3326	161	1	statistical	statistical	ADJ
fnp-3326	161	2	analyses	analysis	NOUN
fnp-3326	161	3	to	to	PART
fnp-3326	161	4	assess	assess	VERB
fnp-3326	161	5	the	the	DET
fnp-3326	161	6	effect	effect	NOUN
fnp-3326	161	7	of	of	ADP
fnp-3326	161	8	the	the	DET
fnp-3326	161	9	experimental	experimental	ADJ
fnp-3326	161	10	conditions	condition	NOUN
fnp-3326	161	11	on	on	ADP
fnp-3326	161	12	the	the	DET
fnp-3326	161	13	log2	log2	PROPN
fnp-3326	161	14	gene	gene	NOUN
fnp-3326	161	15	expression	expression	NOUN
fnp-3326	161	16	levels	level	NOUN
fnp-3326	161	17	were	be	AUX
fnp-3326	161	18	done	do	VERB
fnp-3326	161	19	with	with	ADP
fnp-3326	161	20	linear	linear	ADJ
fnp-3326	161	21	models	model	NOUN
fnp-3326	161	22	using	use	VERB
fnp-3326	161	23	the	the	DET
fnp-3326	161	24	limma	limma	NOUN
fnp-3326	161	25	package	package	NOUN
fnp-3326	161	26	(	(	PUNCT
fnp-3326	161	27	bioconductor	bioconductor	NOUN
fnp-3326	161	28	/	/	SYM
fnp-3326	161	29	r	r	NOUN
fnp-3326	161	30	,	,	PUNCT
fnp-3326	161	31	[	[	X
fnp-3326	161	32	48	48	NUM
fnp-3326	161	33	]	]	PUNCT
fnp-3326	161	34	)	)	PUNCT
fnp-3326	161	35	.	.	PUNCT
fnp-3326	162	1	these	these	DET
fnp-3326	162	2	analyses	analysis	NOUN
fnp-3326	162	3	were	be	AUX
fnp-3326	162	4	implemented	implement	VERB
fnp-3326	162	5	in	in	ADP
fnp-3326	162	6	r	r	NOUN
fnp-3326	162	7	v	v	NUM
fnp-3326	162	8	3.1.1	3.1.1	NUM
fnp-3326	162	9	.	.	PUNCT
fnp-3326	163	1	for	for	ADP
fnp-3326	163	2	the	the	DET
fnp-3326	163	3	statistical	statistical	ADJ
fnp-3326	163	4	modelling	modelling	NOUN
fnp-3326	163	5	of	of	ADP
fnp-3326	163	6	the	the	DET
fnp-3326	163	7	effects	effect	NOUN
fnp-3326	163	8	of	of	ADP
fnp-3326	163	9	the	the	DET
fnp-3326	163	10	il-10	il-10	ADJ
fnp-3326	163	11	treatment	treatment	NOUN
fnp-3326	163	12	on	on	ADP
fnp-3326	163	13	αsyn	αsyn	ADJ
fnp-3326	163	14	counts	count	NOUN
fnp-3326	163	15	,	,	PUNCT
fnp-3326	163	16	as	as	ADV
fnp-3326	163	17	well	well	ADV
fnp-3326	163	18	as	as	ADP
fnp-3326	163	19	infiltration	infiltration	NOUN
fnp-3326	163	20	scores	score	NOUN
fnp-3326	163	21	,	,	PUNCT
fnp-3326	163	22	the	the	DET
fnp-3326	163	23	levels	level	NOUN
fnp-3326	163	24	for	for	ADP
fnp-3326	163	25	igg1(v1)-il10	igg1(v1)-il10	NOUN
fnp-3326	163	26	and	and	CCONJ
fnp-3326	163	27	igg1(v2)-il10	igg1(v2)-il10	PRON
fnp-3326	163	28	treatment	treatment	NOUN
fnp-3326	163	29	were	be	AUX
fnp-3326	163	30	compared	compare	VERB
fnp-3326	163	31	to	to	ADP
fnp-3326	163	32	the	the	DET
fnp-3326	163	33	positive	positive	ADJ
fnp-3326	163	34	(	(	PUNCT
fnp-3326	163	35	vehicle	vehicle	NOUN
fnp-3326	163	36	/	/	SYM
fnp-3326	163	37	dss	dss	NOUN
fnp-3326	163	38	)	)	PUNCT
fnp-3326	163	39	control	control	NOUN
fnp-3326	163	40	.	.	PUNCT
fnp-3326	164	1	additionally	additionally	ADV
fnp-3326	164	2	,	,	PUNCT
fnp-3326	164	3	since	since	SCONJ
fnp-3326	164	4	levels	level	NOUN
fnp-3326	164	5	of	of	ADP
fnp-3326	164	6	the	the	DET
fnp-3326	164	7	control	control	NOUN
fnp-3326	164	8	antibody	antibody	NOUN
fnp-3326	164	9	treatment	treatment	NOUN
fnp-3326	164	10	(	(	PUNCT
fnp-3326	164	11	igg1(v1	igg1(v1	PROPN
fnp-3326	164	12	)	)	PUNCT
fnp-3326	164	13	)	)	PUNCT
fnp-3326	164	14	were	be	AUX
fnp-3326	164	15	very	very	ADV
fnp-3326	164	16	similar	similar	ADJ
fnp-3326	164	17	to	to	ADP
fnp-3326	164	18	the	the	DET
fnp-3326	164	19	positive	positive	ADJ
fnp-3326	164	20	control	control	NOUN
fnp-3326	164	21	,	,	PUNCT
fnp-3326	164	22	the	the	DET
fnp-3326	164	23	two	two	NUM
fnp-3326	164	24	groups	group	NOUN
fnp-3326	164	25	were	be	AUX
fnp-3326	164	26	pooled	pool	VERB
fnp-3326	164	27	in	in	ADP
fnp-3326	164	28	further	further	ADJ
fnp-3326	164	29	contrasts	contrast	NOUN
fnp-3326	164	30	in	in	ADP
fnp-3326	164	31	which	which	PRON
fnp-3326	164	32	effects	effect	NOUN
fnp-3326	164	33	of	of	ADP
fnp-3326	164	34	individual	individual	ADJ
fnp-3326	164	35	antibodies	antibody	NOUN
fnp-3326	164	36	or	or	CCONJ
fnp-3326	164	37	control	control	PROPN
fnp-3326	164	38	igg	igg	PROPN
fnp-3326	164	39	was	be	AUX
fnp-3326	164	40	assessed	assess	VERB
fnp-3326	164	41	.	.	PUNCT
fnp-3326	165	1	for	for	ADP
fnp-3326	165	2	αsyn	αsyn	ADJ
fnp-3326	165	3	counts	count	NOUN
fnp-3326	165	4	in	in	ADP
fnp-3326	165	5	the	the	DET
fnp-3326	165	6	enteric	enteric	ADJ
fnp-3326	165	7	nervous	nervous	ADJ
fnp-3326	165	8	system	system	NOUN
fnp-3326	165	9	,	,	PUNCT
fnp-3326	165	10	a	a	DET
fnp-3326	165	11	linear	linear	ADJ
fnp-3326	165	12	model	model	NOUN
fnp-3326	165	13	on	on	ADP
fnp-3326	165	14	the	the	DET
fnp-3326	165	15	treatment	treatment	NOUN
fnp-3326	165	16	groups	group	NOUN
fnp-3326	165	17	with	with	ADP
fnp-3326	165	18	one	one	NUM
fnp-3326	165	19	-	-	PUNCT
fnp-3326	165	20	degree	degree	NOUN
fnp-3326	165	21	freedom	freedom	NOUN
fnp-3326	165	22	contrasts	contrast	NOUN
fnp-3326	165	23	was	be	AUX
fnp-3326	165	24	applied	apply	VERB
fnp-3326	165	25	.	.	PUNCT
fnp-3326	166	1	for	for	ADP
fnp-3326	166	2	the	the	DET
fnp-3326	166	3	infiltration	infiltration	NOUN
fnp-3326	166	4	score	score	VERB
fnp-3326	166	5	a	a	DET
fnp-3326	166	6	kruskal	kruskal	PROPN
fnp-3326	166	7	-	-	PUNCT
fnp-3326	166	8	wallis	wallis	PROPN
fnp-3326	166	9	test	test	NOUN
fnp-3326	166	10	,	,	PUNCT
fnp-3326	166	11	with	with	ADP
fnp-3326	166	12	the	the	DET
fnp-3326	166	13	same	same	ADJ
fnp-3326	166	14	contrasts	contrast	NOUN
fnp-3326	166	15	,	,	PUNCT
fnp-3326	166	16	was	be	AUX
fnp-3326	166	17	used	use	VERB
fnp-3326	166	18	.	.	PUNCT
fnp-3326	167	1	all	all	DET
fnp-3326	167	2	statistical	statistical	ADJ
fnp-3326	167	3	tests	test	NOUN
fnp-3326	167	4	were	be	AUX
fnp-3326	167	5	two	two	NUM
fnp-3326	167	6	-	-	PUNCT
fnp-3326	167	7	tailed	tail	VERB
fnp-3326	167	8	with	with	ADP
fnp-3326	167	9	a	a	DET
fnp-3326	167	10	significance	significance	NOUN
fnp-3326	167	11	level	level	NOUN
fnp-3326	167	12	of	of	ADP
fnp-3326	167	13	p	p	NOUN
fnp-3326	167	14	<	<	NOUN
fnp-3326	167	15	0.05	0.05	NUM
fnp-3326	167	16	.	.	PUNCT
fnp-3326	168	1	for	for	ADP
fnp-3326	168	2	the	the	DET
fnp-3326	168	3	statistical	statistical	ADJ
fnp-3326	168	4	analysis	analysis	NOUN
fnp-3326	168	5	of	of	ADP
fnp-3326	168	6	the	the	DET
fnp-3326	168	7	pser129	pser129	PROPN
fnp-3326	168	8	αsyn	αsyn	ADJ
fnp-3326	168	9	brain	brain	NOUN
fnp-3326	168	10	pathology	pathology	NOUN
fnp-3326	168	11	,	,	PUNCT
fnp-3326	168	12	zero	zero	NUM
fnp-3326	168	13	-	-	PUNCT
fnp-3326	168	14	inflated	inflate	VERB
fnp-3326	168	15	negative	negative	ADJ
fnp-3326	168	16	-	-	PUNCT
fnp-3326	168	17	binomial	binomial	ADJ
fnp-3326	168	18	mixed	mixed	ADJ
fnp-3326	168	19	-	-	PUNCT
fnp-3326	168	20	effects	effect	NOUN
fnp-3326	168	21	models	model	NOUN
fnp-3326	168	22	with	with	ADP
fnp-3326	168	23	a	a	DET
fnp-3326	168	24	random	random	ADJ
fnp-3326	168	25	intercept	intercept	NOUN
fnp-3326	168	26	for	for	ADP
fnp-3326	168	27	each	each	DET
fnp-3326	168	28	sample	sample	NOUN
fnp-3326	168	29	and	and	CCONJ
fnp-3326	168	30	variance	variance	NOUN
fnp-3326	168	31	assumed	assume	VERB
fnp-3326	168	32	to	to	PART
fnp-3326	168	33	increase	increase	VERB
fnp-3326	168	34	linearly	linearly	ADV
fnp-3326	168	35	with	with	ADP
fnp-3326	168	36	the	the	DET
fnp-3326	168	37	mean	mean	NOUN
fnp-3326	168	38	(	(	PUNCT
fnp-3326	168	39	verified	verify	VERB
fnp-3326	168	40	against	against	ADP
fnp-3326	168	41	a	a	DET
fnp-3326	168	42	quadratic	quadratic	ADJ
fnp-3326	168	43	increase	increase	NOUN
fnp-3326	168	44	using	use	VERB
fnp-3326	168	45	akaike	akaike	ADJ
fnp-3326	168	46	information	information	NOUN
fnp-3326	168	47	criterion	criterion	NOUN
fnp-3326	169	1	[	[	X
fnp-3326	169	2	aic	aic	X
fnp-3326	169	3	]	]	X
fnp-3326	169	4	and	and	CCONJ
fnp-3326	169	5	bayesian	bayesian	NOUN
fnp-3326	169	6	information	information	NOUN
fnp-3326	169	7	criterion	criterion	NOUN
fnp-3326	169	8	[	[	X
fnp-3326	169	9	bic	bic	NOUN
fnp-3326	169	10	]	]	PUNCT
fnp-3326	169	11	)	)	PUNCT
fnp-3326	169	12	were	be	AUX
fnp-3326	169	13	used	use	VERB
fnp-3326	169	14	to	to	PART
fnp-3326	169	15	analyze	analyze	VERB
fnp-3326	169	16	the	the	DET
fnp-3326	169	17	dataset	dataset	NOUN
fnp-3326	169	18	via	via	ADP
fnp-3326	169	19	the	the	DET
fnp-3326	169	20	‘	'	PUNCT
fnp-3326	169	21	glmmtmb	glmmtmb	NOUN
fnp-3326	169	22	’	'	PUNCT
fnp-3326	169	23	package	package	NOUN
fnp-3326	169	24	in	in	ADP
fnp-3326	169	25	r	r	NOUN
fnp-3326	169	26	v	v	NUM
fnp-3326	169	27	3.4.4	3.4.4	NUM
fnp-3326	169	28	.	.	PUNCT
fnp-3326	170	1	linear	linear	PROPN
fnp-3326	170	2	contrasts	contrast	VERB
fnp-3326	170	3	with	with	ADP
fnp-3326	170	4	false	false	ADJ
fnp-3326	170	5	discovery	discovery	NOUN
fnp-3326	170	6	rate	rate	NOUN
fnp-3326	170	7	(	(	PUNCT
fnp-3326	170	8	fdr	fdr	PROPN
fnp-3326	170	9	)	)	PUNCT
fnp-3326	170	10	adjustments	adjustment	NOUN
fnp-3326	170	11	were	be	AUX
fnp-3326	170	12	then	then	ADV
fnp-3326	170	13	used	use	VERB
fnp-3326	170	14	to	to	PART
fnp-3326	170	15	test	test	VERB
fnp-3326	170	16	our	our	PRON
fnp-3326	170	17	hypotheses	hypothesis	NOUN
fnp-3326	170	18	and	and	CCONJ
fnp-3326	170	19	account	account	VERB
fnp-3326	170	20	for	for	ADP
fnp-3326	170	21	multiple	multiple	ADJ
fnp-3326	170	22	testing	testing	NOUN
fnp-3326	170	23	(	(	PUNCT
fnp-3326	170	24	for	for	ADP
fnp-3326	170	25	brain	brain	NOUN
fnp-3326	170	26	area	area	NOUN
fnp-3326	170	27	and	and	CCONJ
fnp-3326	170	28	experimental	experimental	ADJ
fnp-3326	170	29	group	group	NOUN
fnp-3326	170	30	)	)	PUNCT
fnp-3326	170	31	.	.	PUNCT
fnp-3326	171	1	results	result	VERB
fnp-3326	171	2	experimental	experimental	ADJ
fnp-3326	171	3	colitis	colitis	NOUN
fnp-3326	171	4	exacerbates	exacerbate	VERB
fnp-3326	171	5	αsyn	αsyn	ADJ
fnp-3326	171	6	load	load	NOUN
fnp-3326	171	7	in	in	ADP
fnp-3326	171	8	the	the	DET
fnp-3326	171	9	submucosal	submucosal	NOUN
fnp-3326	171	10	plexus	plexus	NOUN
fnp-3326	171	11	of	of	ADP
fnp-3326	171	12	αsyn	αsyn	ADJ
fnp-3326	171	13	transgenic	transgenic	NOUN
fnp-3326	171	14	and	and	CCONJ
fnp-3326	171	15	wild	wild	ADJ
fnp-3326	171	16	type	type	NOUN
fnp-3326	171	17	mice	mouse	NOUN
fnp-3326	171	18	during	during	ADP
fnp-3326	171	19	the	the	DET
fnp-3326	171	20	process	process	NOUN
fnp-3326	171	21	of	of	ADP
fnp-3326	171	22	further	far	ADV
fnp-3326	171	23	characterizing	characterize	VERB
fnp-3326	171	24	a	a	DET
fnp-3326	171	25	(	(	PUNCT
fnp-3326	171	26	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	171	27	transgenic	transgenic	NOUN
fnp-3326	171	28	mouse	mouse	NOUN
fnp-3326	171	29	line	line	NOUN
fnp-3326	172	1	[	[	X
fnp-3326	172	2	41	41	NUM
fnp-3326	172	3	]	]	PUNCT
fnp-3326	172	4	,	,	PUNCT
fnp-3326	172	5	we	we	PRON
fnp-3326	172	6	detected	detect	VERB
fnp-3326	172	7	by	by	ADP
fnp-3326	172	8	immunohistochemistry	immunohistochemistry	NOUN
fnp-3326	172	9	human	human	PROPN
fnp-3326	172	10	αsyn	αsyn	PROPN
fnp-3326	172	11	accumulation	accumulation	NOUN
fnp-3326	172	12	in	in	ADP
fnp-3326	172	13	all	all	DET
fnp-3326	172	14	innervated	innervated	ADJ
fnp-3326	172	15	organs	organ	NOUN
fnp-3326	172	16	that	that	PRON
fnp-3326	172	17	were	be	AUX
fnp-3326	172	18	analyzed	analyze	VERB
fnp-3326	172	19	(	(	PUNCT
fnp-3326	172	20	suppl	suppl	PROPN
fnp-3326	172	21	.	.	PUNCT
fnp-3326	172	22	fig	fig	NOUN
fnp-3326	172	23	.	.	PUNCT
fnp-3326	173	1	1	1	NUM
fnp-3326	173	2	)	)	PUNCT
fnp-3326	173	3	.	.	PUNCT
fnp-3326	174	1	to	to	PART
fnp-3326	174	2	examine	examine	VERB
fnp-3326	174	3	the	the	DET
fnp-3326	174	4	localization	localization	NOUN
fnp-3326	174	5	of	of	ADP
fnp-3326	174	6	αsyn	αsyn	ADJ
fnp-3326	174	7	inclusions	inclusion	NOUN
fnp-3326	174	8	in	in	ADP
fnp-3326	174	9	nervous	nervous	ADJ
fnp-3326	174	10	structures	structure	NOUN
fnp-3326	174	11	in	in	ADP
fnp-3326	174	12	the	the	DET
fnp-3326	174	13	ens	en	NOUN
fnp-3326	174	14	,	,	PUNCT
fnp-3326	174	15	we	we	PRON
fnp-3326	174	16	performed	perform	VERB
fnp-3326	174	17	an	an	DET
fnp-3326	174	18	immunofluorescent	immunofluorescent	NOUN
fnp-3326	174	19	co	co	NOUN
fnp-3326	174	20	-	-	ADJ
fnp-3326	174	21	staining	stain	VERB
fnp-3326	174	22	for	for	ADP
fnp-3326	174	23	human	human	ADJ
fnp-3326	174	24	αsyn	αsyn	NOUN
fnp-3326	174	25	(	(	PUNCT
fnp-3326	174	26	clone	clone	NOUN
fnp-3326	174	27	211	211	NUM
fnp-3326	174	28	)	)	PUNCT
fnp-3326	174	29	and	and	CCONJ
fnp-3326	174	30	peripherin	peripherin	NOUN
fnp-3326	174	31	,	,	PUNCT
fnp-3326	174	32	a	a	DET
fnp-3326	174	33	specific	specific	ADJ
fnp-3326	174	34	marker	marker	NOUN
fnp-3326	174	35	for	for	ADP
fnp-3326	174	36	peripheral	peripheral	ADJ
fnp-3326	174	37	nerves	nerve	NOUN
fnp-3326	174	38	.	.	PUNCT
fnp-3326	175	1	by	by	ADP
fnp-3326	175	2	applying	apply	VERB
fnp-3326	175	3	confocal	confocal	ADJ
fnp-3326	175	4	microscopy	microscopy	NOUN
fnp-3326	175	5	,	,	PUNCT
fnp-3326	175	6	we	we	PRON
fnp-3326	175	7	established	establish	VERB
fnp-3326	175	8	a	a	DET
fnp-3326	175	9	process	process	NOUN
fnp-3326	175	10	and	and	CCONJ
fnp-3326	175	11	protocol	protocol	NOUN
fnp-3326	175	12	to	to	PART
fnp-3326	175	13	identify	identify	VERB
fnp-3326	175	14	myenteric	myenteric	ADJ
fnp-3326	175	15	and	and	CCONJ
fnp-3326	175	16	submucosal	submucosal	NOUN
fnp-3326	175	17	plexuses	plexus	NOUN
fnp-3326	175	18	in	in	ADP
fnp-3326	175	19	order	order	NOUN
fnp-3326	175	20	to	to	PART
fnp-3326	175	21	quantify	quantify	VERB
fnp-3326	175	22	the	the	DET
fnp-3326	175	23	αsyn	αsyn	ADJ
fnp-3326	175	24	inclusions	inclusion	NOUN
fnp-3326	175	25	found	find	VERB
fnp-3326	175	26	in	in	ADP
fnp-3326	175	27	the	the	DET
fnp-3326	175	28	nerve	nerve	NOUN
fnp-3326	175	29	cells	cell	NOUN
fnp-3326	175	30	of	of	ADP
fnp-3326	175	31	the	the	DET
fnp-3326	175	32	ganglia	ganglia	NOUN
fnp-3326	175	33	in	in	ADP
fnp-3326	175	34	the	the	DET
fnp-3326	175	35	colon	colon	NOUN
fnp-3326	175	36	.	.	PUNCT
fnp-3326	176	1	the	the	DET
fnp-3326	176	2	intracellular	intracellular	ADJ
fnp-3326	176	3	presence	presence	NOUN
fnp-3326	176	4	of	of	ADP
fnp-3326	176	5	the	the	DET
fnp-3326	176	6	irregularly	irregularly	ADV
fnp-3326	176	7	sized	sized	ADJ
fnp-3326	176	8	and	and	CCONJ
fnp-3326	176	9	shaped	shape	VERB
fnp-3326	176	10	αsyn	αsyn	ADJ
fnp-3326	176	11	inclusion	inclusion	NOUN
fnp-3326	176	12	bodies	body	NOUN
fnp-3326	176	13	was	be	AUX
fnp-3326	176	14	confirmed	confirm	VERB
fnp-3326	176	15	in	in	ADP
fnp-3326	176	16	2d	2d	NUM
fnp-3326	176	17	z	z	NOUN
fnp-3326	176	18	-	-	PUNCT
fnp-3326	176	19	stacks	stack	NOUN
fnp-3326	176	20	of	of	ADP
fnp-3326	176	21	rotated	rotate	VERB
fnp-3326	176	22	confocal	confocal	ADJ
fnp-3326	176	23	images	image	NOUN
fnp-3326	176	24	(	(	PUNCT
fnp-3326	176	25	fig	fig	NOUN
fnp-3326	176	26	.	.	PUNCT
fnp-3326	177	1	1a	1a	NOUN
fnp-3326	177	2	)	)	PUNCT
fnp-3326	177	3	.	.	PUNCT
fnp-3326	178	1	we	we	PRON
fnp-3326	178	2	observed	observe	VERB
fnp-3326	178	3	an	an	DET
fnp-3326	178	4	age	age	NOUN
fnp-3326	178	5	-	-	PUNCT
fnp-3326	178	6	dependent	dependent	ADJ
fnp-3326	178	7	(	(	PUNCT
fnp-3326	178	8	mice	mouse	NOUN
fnp-3326	178	9	aged	age	VERB
fnp-3326	178	10	3	3	NUM
fnp-3326	178	11	months	month	NOUN
fnp-3326	178	12	versus	versus	ADP
fnp-3326	178	13	12	12	NUM
fnp-3326	178	14	months	month	NOUN
fnp-3326	178	15	)	)	PUNCT
fnp-3326	178	16	increase	increase	NOUN
fnp-3326	178	17	of	of	ADP
fnp-3326	178	18	baseline	baseline	ADJ
fnp-3326	178	19	human	human	ADJ
fnp-3326	178	20	αsyn	αsyn	ADJ
fnp-3326	178	21	inclusions	inclusion	NOUN
fnp-3326	178	22	in	in	ADP
fnp-3326	178	23	both	both	DET
fnp-3326	178	24	plexuses	plexus	NOUN
fnp-3326	178	25	(	(	PUNCT
fnp-3326	178	26	fig	fig	NOUN
fnp-3326	178	27	.	.	PUNCT
fnp-3326	178	28	1b	1b	NUM
fnp-3326	178	29	)	)	PUNCT
fnp-3326	178	30	.	.	PUNCT
fnp-3326	179	1	given	give	VERB
fnp-3326	179	2	the	the	DET
fnp-3326	179	3	clinical	clinical	ADJ
fnp-3326	179	4	and	and	CCONJ
fnp-3326	179	5	epidemiological	epidemiological	ADJ
fnp-3326	179	6	link	link	NOUN
fnp-3326	179	7	between	between	ADP
fnp-3326	179	8	ibd	ibd	PROPN
fnp-3326	179	9	and	and	CCONJ
fnp-3326	179	10	pd	pd	PROPN
fnp-3326	179	11	,	,	PUNCT
fnp-3326	179	12	we	we	PRON
fnp-3326	179	13	wanted	want	VERB
fnp-3326	179	14	to	to	PART
fnp-3326	179	15	test	test	VERB
fnp-3326	179	16	whether	whether	SCONJ
fnp-3326	179	17	different	different	ADJ
fnp-3326	179	18	types	type	NOUN
fnp-3326	179	19	and	and	CCONJ
fnp-3326	179	20	strengths	strength	NOUN
fnp-3326	179	21	of	of	ADP
fnp-3326	179	22	ibd	ibd	NOUN
fnp-3326	179	23	-	-	PUNCT
fnp-3326	179	24	related	relate	VERB
fnp-3326	179	25	experimental	experimental	ADJ
fnp-3326	179	26	inflammation	inflammation	NOUN
fnp-3326	179	27	in	in	ADP
fnp-3326	179	28	the	the	DET
fnp-3326	179	29	colon	colon	NOUN
fnp-3326	179	30	exacerbates	exacerbate	VERB
fnp-3326	179	31	this	this	DET
fnp-3326	179	32	local	local	ADJ
fnp-3326	179	33	accumulation	accumulation	NOUN
fnp-3326	179	34	of	of	ADP
fnp-3326	179	35	αsyn	αsyn	NOUN
fnp-3326	179	36	acutely	acutely	ADV
fnp-3326	179	37	(	(	PUNCT
fnp-3326	179	38	e.g.	e.g.	ADV
fnp-3326	179	39	,	,	PUNCT
fnp-3326	179	40	within	within	ADP
fnp-3326	179	41	a	a	DET
fnp-3326	179	42	few	few	ADJ
fnp-3326	179	43	days	day	NOUN
fnp-3326	179	44	or	or	CCONJ
fnp-3326	179	45	weeks	week	NOUN
fnp-3326	179	46	)	)	PUNCT
fnp-3326	179	47	and	and	CCONJ
fnp-3326	179	48	how	how	SCONJ
fnp-3326	179	49	the	the	DET
fnp-3326	179	50	age	age	NOUN
fnp-3326	179	51	of	of	ADP
fnp-3326	179	52	the	the	DET
fnp-3326	179	53	αsyn	αsyn	ADJ
fnp-3326	179	54	transgenic	transgenic	NOUN
fnp-3326	179	55	mice	mouse	NOUN
fnp-3326	179	56	may	may	AUX
fnp-3326	179	57	influence	influence	VERB
fnp-3326	179	58	the	the	DET
fnp-3326	179	59	outcome	outcome	NOUN
fnp-3326	179	60	.	.	PUNCT
fnp-3326	180	1	administration	administration	NOUN
fnp-3326	180	2	of	of	ADP
fnp-3326	180	3	dextran	dextran	ADJ
fnp-3326	180	4	sulfate	sulfate	NOUN
fnp-3326	180	5	sodium	sodium	NOUN
fnp-3326	180	6	(	(	PUNCT
fnp-3326	180	7	dss	dss	NOUN
fnp-3326	180	8	)	)	PUNCT
fnp-3326	180	9	in	in	ADP
fnp-3326	180	10	the	the	DET
fnp-3326	180	11	drinking	drinking	NOUN
fnp-3326	180	12	water	water	NOUN
fnp-3326	180	13	in	in	ADP
fnp-3326	180	14	acute	acute	ADJ
fnp-3326	180	15	or	or	CCONJ
fnp-3326	180	16	chronic	chronic	ADJ
fnp-3326	180	17	dosing	dose	VERB
fnp-3326	180	18	paradigms	paradigm	NOUN
fnp-3326	180	19	are	be	AUX
fnp-3326	180	20	well	well	ADV
fnp-3326	180	21	-	-	PUNCT
fnp-3326	180	22	established	establish	VERB
fnp-3326	180	23	mouse	mouse	NOUN
fnp-3326	180	24	models	model	NOUN
fnp-3326	180	25	of	of	ADP
fnp-3326	180	26	experimental	experimental	ADJ
fnp-3326	180	27	colitis	colitis	NOUN
fnp-3326	180	28	mimicking	mimic	VERB
fnp-3326	180	29	aspects	aspect	NOUN
fnp-3326	180	30	of	of	ADP
fnp-3326	180	31	ibd	ibd	NOUN
fnp-3326	180	32	,	,	PUNCT
fnp-3326	180	33	i.e.	i.e.	X
fnp-3326	180	34	,	,	PUNCT
fnp-3326	180	35	by	by	ADP
fnp-3326	180	36	exhibiting	exhibit	VERB
fnp-3326	180	37	infiltration	infiltration	NOUN
fnp-3326	180	38	of	of	ADP
fnp-3326	180	39	leukocytes	leukocyte	NOUN
fnp-3326	180	40	into	into	ADP
fnp-3326	180	41	the	the	DET
fnp-3326	180	42	submucosa	submucosa	NOUN
fnp-3326	180	43	with	with	ADP
fnp-3326	180	44	various	various	ADJ
fnp-3326	180	45	degrees	degree	NOUN
fnp-3326	180	46	of	of	ADP
fnp-3326	180	47	destruction	destruction	NOUN
fnp-3326	180	48	of	of	ADP
fnp-3326	180	49	the	the	DET
fnp-3326	180	50	colonic	colonic	ADJ
fnp-3326	180	51	mucosa	mucosa	NOUN
fnp-3326	180	52	and	and	CCONJ
fnp-3326	180	53	submucosa	submucosa	NOUN
fnp-3326	180	54	[	[	X
fnp-3326	180	55	49	49	NUM
fnp-3326	180	56	]	]	PUNCT
fnp-3326	180	57	.	.	PUNCT
fnp-3326	181	1	it	it	PRON
fnp-3326	181	2	is	be	AUX
fnp-3326	181	3	well	well	ADV
fnp-3326	181	4	-	-	PUNCT
fnp-3326	181	5	known	know	VERB
fnp-3326	181	6	that	that	SCONJ
fnp-3326	181	7	the	the	DET
fnp-3326	181	8	effects	effect	NOUN
fnp-3326	181	9	induced	induce	VERB
fnp-3326	181	10	by	by	ADP
fnp-3326	181	11	the	the	DET
fnp-3326	181	12	dss	dss	NOUN
fnp-3326	181	13	paradigm	paradigm	NOUN
fnp-3326	181	14	can	can	AUX
fnp-3326	181	15	vary	vary	VERB
fnp-3326	181	16	substantially	substantially	ADV
fnp-3326	181	17	based	base	VERB
fnp-3326	181	18	on	on	ADP
fnp-3326	181	19	the	the	DET
fnp-3326	181	20	genetic	genetic	ADJ
fnp-3326	181	21	background	background	NOUN
fnp-3326	181	22	of	of	ADP
fnp-3326	181	23	the	the	DET
fnp-3326	181	24	mice	mouse	NOUN
fnp-3326	181	25	and	and	CCONJ
fnp-3326	181	26	due	due	ADP
fnp-3326	181	27	to	to	ADP
fnp-3326	181	28	different	different	ADJ
fnp-3326	181	29	animal	animal	NOUN
fnp-3326	181	30	housing	housing	NOUN
fnp-3326	181	31	environments	environment	NOUN
fnp-3326	181	32	.	.	PUNCT
fnp-3326	182	1	thus	thus	ADV
fnp-3326	182	2	,	,	PUNCT
fnp-3326	182	3	in	in	ADP
fnp-3326	182	4	order	order	NOUN
fnp-3326	182	5	to	to	PART
fnp-3326	182	6	establish	establish	VERB
fnp-3326	182	7	the	the	DET
fnp-3326	182	8	dss	dss	NOUN
fnp-3326	182	9	paradigm	paradigm	NOUN
fnp-3326	182	10	in	in	ADP
fnp-3326	182	11	our	our	PRON
fnp-3326	182	12	environment	environment	NOUN
fnp-3326	182	13	and	and	CCONJ
fnp-3326	182	14	with	with	ADP
fnp-3326	182	15	our	our	PRON
fnp-3326	182	16	mice	mouse	NOUN
fnp-3326	182	17	,	,	PUNCT
fnp-3326	182	18	we	we	PRON
fnp-3326	182	19	first	first	ADV
fnp-3326	182	20	tested	test	VERB
fnp-3326	182	21	the	the	DET
fnp-3326	182	22	effect	effect	NOUN
fnp-3326	182	23	of	of	ADP
fnp-3326	182	24	dss	dss	NOUN
fnp-3326	182	25	administration	administration	NOUN
fnp-3326	182	26	at	at	ADP
fnp-3326	182	27	different	different	ADJ
fnp-3326	182	28	doses	dose	NOUN
fnp-3326	182	29	and	and	CCONJ
fnp-3326	182	30	durations	duration	NOUN
fnp-3326	182	31	in	in	ADP
fnp-3326	182	32	the	the	DET
fnp-3326	182	33	(	(	PUNCT
fnp-3326	182	34	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	182	35	transgenic	transgenic	NOUN
fnp-3326	182	36	mice	mouse	NOUN
fnp-3326	182	37	(	(	PUNCT
fnp-3326	182	38	fig	fig	NOUN
fnp-3326	182	39	.	.	PUNCT
fnp-3326	183	1	1c	1c	NOUN
fnp-3326	183	2	)	)	PUNCT
fnp-3326	183	3	.	.	PUNCT
fnp-3326	184	1	we	we	PRON
fnp-3326	184	2	observed	observe	VERB
fnp-3326	184	3	that	that	SCONJ
fnp-3326	184	4	leukocyte	leukocyte	NOUN
fnp-3326	184	5	infiltration	infiltration	NOUN
fnp-3326	184	6	was	be	AUX
fnp-3326	184	7	appropriately	appropriately	ADV
fnp-3326	184	8	modulated	modulate	VERB
fnp-3326	184	9	by	by	ADP
fnp-3326	184	10	the	the	DET
fnp-3326	184	11	acute	acute	PROPN
fnp-3326	184	12	dose	dose	PROPN
fnp-3326	184	13	(	(	PUNCT
fnp-3326	184	14	1	1	NUM
fnp-3326	184	15	%	%	NOUN
fnp-3326	184	16	or	or	CCONJ
fnp-3326	184	17	2.5	2.5	NUM
fnp-3326	184	18	%	%	NOUN
fnp-3326	184	19	dss	dss	NOUN
fnp-3326	184	20	for	for	ADP
fnp-3326	184	21	5	5	NUM
fnp-3326	184	22	days	day	NOUN
fnp-3326	184	23	followed	follow	VERB
fnp-3326	184	24	by	by	ADP
fnp-3326	184	25	2	2	NUM
fnp-3326	184	26	days	day	NOUN
fnp-3326	184	27	drinking	drink	VERB
fnp-3326	184	28	water	water	NOUN
fnp-3326	184	29	)	)	PUNCT
fnp-3326	184	30	and	and	CCONJ
fnp-3326	184	31	chronic	chronic	ADJ
fnp-3326	184	32	constant	constant	ADJ
fnp-3326	184	33	dose	dose	NOUN
fnp-3326	184	34	(	(	PUNCT
fnp-3326	184	35	1	1	NUM
fnp-3326	184	36	%	%	NOUN
fnp-3326	184	37	or	or	CCONJ
fnp-3326	184	38	2.5	2.5	NUM
fnp-3326	184	39	%	%	NOUN
fnp-3326	184	40	dss	dss	NOUN
fnp-3326	184	41	alternating	alternating	NOUN
fnp-3326	184	42	with	with	ADP
fnp-3326	184	43	normal	normal	ADJ
fnp-3326	184	44	drinking	drinking	NOUN
fnp-3326	184	45	water	water	NOUN
fnp-3326	184	46	for	for	ADP
fnp-3326	184	47	28	28	NUM
fnp-3326	184	48	days	day	NOUN
fnp-3326	184	49	,	,	PUNCT
fnp-3326	184	50	respectively	respectively	ADV
fnp-3326	184	51	)	)	PUNCT
fnp-3326	184	52	dss	dss	NOUN
fnp-3326	184	53	paradigms	paradigms	NOUN
fnp-3326	184	54	(	(	PUNCT
fnp-3326	184	55	fig	fig	NOUN
fnp-3326	184	56	.	.	PUNCT
fnp-3326	184	57	1d	1d	NUM
fnp-3326	184	58	and	and	CCONJ
fnp-3326	184	59	2a	2a	NUM
fnp-3326	184	60	)	)	PUNCT
fnp-3326	184	61	.	.	PUNCT
fnp-3326	185	1	in	in	ADP
fnp-3326	185	2	the	the	DET
fnp-3326	185	3	same	same	ADJ
fnp-3326	185	4	experiment	experiment	NOUN
fnp-3326	185	5	,	,	PUNCT
fnp-3326	185	6	we	we	PRON
fnp-3326	185	7	wanted	want	VERB
fnp-3326	185	8	to	to	PART
fnp-3326	185	9	test	test	VERB
fnp-3326	185	10	for	for	ADP
fnp-3326	185	11	an	an	DET
fnp-3326	185	12	age	age	NOUN
fnp-3326	185	13	effect	effect	NOUN
fnp-3326	185	14	on	on	ADP
fnp-3326	185	15	a	a	DET
fnp-3326	185	16	potential	potential	ADJ
fnp-3326	185	17	aggravation	aggravation	NOUN
fnp-3326	185	18	of	of	ADP
fnp-3326	185	19	αsyn	αsyn	ADJ
fnp-3326	185	20	accumulation	accumulation	NOUN
fnp-3326	185	21	in	in	ADP
fnp-3326	185	22	the	the	DET
fnp-3326	185	23	ens	ens	NOUN
fnp-3326	185	24	and	and	CCONJ
fnp-3326	185	25	applied	apply	VERB
fnp-3326	185	26	the	the	DET
fnp-3326	185	27	acute	acute	NOUN
fnp-3326	185	28	dose	dose	NOUN
fnp-3326	185	29	paradigm	paradigm	NOUN
fnp-3326	185	30	on	on	ADP
fnp-3326	185	31	3	3	NUM
fnp-3326	185	32	-	-	PUNCT
fnp-3326	185	33	month	month	NOUN
fnp-3326	185	34	-	-	PUNCT
fnp-3326	185	35	old	old	ADJ
fnp-3326	185	36	mice	mouse	NOUN
fnp-3326	185	37	and	and	CCONJ
fnp-3326	185	38	the	the	DET
fnp-3326	185	39	chronic	chronic	ADJ
fnp-3326	185	40	dose	dose	NOUN
fnp-3326	185	41	paradigm	paradigm	NOUN
fnp-3326	185	42	was	be	AUX
fnp-3326	185	43	started	start	VERB
fnp-3326	185	44	at	at	ADP
fnp-3326	185	45	the	the	DET
fnp-3326	185	46	age	age	NOUN
fnp-3326	185	47	of	of	ADP
fnp-3326	185	48	5	5	NUM
fnp-3326	185	49	months	month	NOUN
fnp-3326	185	50	leading	lead	VERB
fnp-3326	185	51	to	to	ADP
fnp-3326	185	52	a	a	DET
fnp-3326	185	53	final	final	ADJ
fnp-3326	185	54	age	age	NOUN
fnp-3326	185	55	of	of	ADP
fnp-3326	185	56	6	6	NUM
fnp-3326	185	57	months	month	NOUN
fnp-3326	185	58	at	at	ADP
fnp-3326	185	59	analysis	analysis	NOUN
fnp-3326	185	60	of	of	ADP
fnp-3326	185	61	the	the	DET
fnp-3326	185	62	mice	mouse	NOUN
fnp-3326	185	63	.	.	PUNCT
fnp-3326	186	1	in	in	ADP
fnp-3326	186	2	the	the	DET
fnp-3326	186	3	acute	acute	ADJ
fnp-3326	186	4	dss	dss	NOUN
fnp-3326	186	5	dosing	dosing	NOUN
fnp-3326	186	6	paradigm	paradigm	NOUN
fnp-3326	186	7	with	with	ADP
fnp-3326	186	8	mice	mouse	NOUN
fnp-3326	186	9	at	at	ADP
fnp-3326	186	10	the	the	DET
fnp-3326	186	11	age	age	NOUN
fnp-3326	186	12	of	of	ADP
fnp-3326	186	13	3	3	NUM
fnp-3326	186	14	months	month	NOUN
fnp-3326	186	15	,	,	PUNCT
fnp-3326	186	16	2.5	2.5	NUM
fnp-3326	186	17	%	%	NOUN
fnp-3326	186	18	,	,	PUNCT
fnp-3326	186	19	but	but	CCONJ
fnp-3326	186	20	not	not	PART
fnp-3326	186	21	1	1	NUM
fnp-3326	186	22	%	%	NOUN
fnp-3326	186	23	,	,	PUNCT
fnp-3326	186	24	dss	dss	NOUN
fnp-3326	186	25	triggered	trigger	VERB
fnp-3326	186	26	intracellular	intracellular	ADJ
fnp-3326	186	27	accumulation	accumulation	NOUN
fnp-3326	186	28	of	of	ADP
fnp-3326	186	29	αsyn	αsyn	NOUN
fnp-3326	186	30	in	in	ADP
fnp-3326	186	31	peripherin	peripherin	ADJ
fnp-3326	186	32	positive	positive	ADJ
fnp-3326	186	33	nerve	nerve	NOUN
fnp-3326	186	34	cells	cell	NOUN
fnp-3326	186	35	of	of	ADP
fnp-3326	186	36	the	the	DET
fnp-3326	186	37	submucosal	submucosal	NOUN
fnp-3326	186	38	plexus	plexus	NOUN
fnp-3326	186	39	(	(	PUNCT
fnp-3326	186	40	fig	fig	NOUN
fnp-3326	186	41	.	.	PUNCT
fnp-3326	187	1	2a	2a	NUM
fnp-3326	187	2	,	,	PUNCT
fnp-3326	187	3	b	b	NOUN
fnp-3326	187	4	)	)	PUNCT
fnp-3326	187	5	.	.	PUNCT
fnp-3326	188	1	in	in	ADP
fnp-3326	188	2	the	the	DET
fnp-3326	188	3	28	28	NUM
fnp-3326	188	4	-	-	PUNCT
fnp-3326	188	5	day	day	NOUN
fnp-3326	188	6	chronic	chronic	ADJ
fnp-3326	188	7	constant	constant	ADJ
fnp-3326	188	8	dss	dss	NOUN
fnp-3326	188	9	dose	dose	NOUN
fnp-3326	188	10	paradigm	paradigm	NOUN
fnp-3326	188	11	in	in	ADP
fnp-3326	188	12	mice	mouse	NOUN
fnp-3326	188	13	aged	age	VERB
fnp-3326	188	14	6	6	NUM
fnp-3326	188	15	months	month	NOUN
fnp-3326	188	16	(	(	PUNCT
fnp-3326	188	17	fig	fig	NOUN
fnp-3326	188	18	.	.	PUNCT
fnp-3326	189	1	1c	1c	NOUN
fnp-3326	189	2	and	and	CCONJ
fnp-3326	189	3	2a	2a	NUM
fnp-3326	189	4	)	)	PUNCT
fnp-3326	189	5	,	,	PUNCT
fnp-3326	189	6	we	we	PRON
fnp-3326	189	7	observed	observe	VERB
fnp-3326	189	8	that	that	SCONJ
fnp-3326	189	9	the	the	DET
fnp-3326	189	10	1	1	NUM
fnp-3326	189	11	%	%	NOUN
fnp-3326	189	12	constant	constant	ADJ
fnp-3326	189	13	chronic	chronic	ADJ
fnp-3326	189	14	dss	dss	NOUN
fnp-3326	189	15	dose	dose	NOUN
fnp-3326	189	16	showed	show	VERB
fnp-3326	189	17	a	a	DET
fnp-3326	189	18	similar	similar	ADJ
fnp-3326	189	19	degree	degree	NOUN
fnp-3326	189	20	of	of	ADP
fnp-3326	189	21	αsyn	αsyn	ADJ
fnp-3326	189	22	inclusions	inclusion	NOUN
fnp-3326	189	23	as	as	ADP
fnp-3326	189	24	the	the	DET
fnp-3326	189	25	3	3	NUM
fnp-3326	189	26	-	-	PUNCT
fnp-3326	189	27	month	month	NOUN
fnp-3326	189	28	-	-	PUNCT
fnp-3326	189	29	old	old	ADJ
fnp-3326	189	30	mice	mouse	NOUN
fnp-3326	189	31	which	which	PRON
fnp-3326	189	32	were	be	AUX
fnp-3326	189	33	on	on	ADP
fnp-3326	189	34	an	an	DET
fnp-3326	189	35	acute	acute	ADJ
fnp-3326	189	36	2.5	2.5	NUM
fnp-3326	189	37	%	%	NOUN
fnp-3326	189	38	dss	dss	NOUN
fnp-3326	189	39	dose	dose	NOUN
fnp-3326	189	40	paradigm	paradigm	NOUN
fnp-3326	189	41	.	.	PUNCT
fnp-3326	190	1	in	in	ADP
fnp-3326	190	2	addition	addition	NOUN
fnp-3326	190	3	,	,	PUNCT
fnp-3326	190	4	mice	mouse	NOUN
fnp-3326	190	5	previously	previously	ADV
fnp-3326	190	6	exposed	expose	VERB
fnp-3326	190	7	to	to	ADP
fnp-3326	190	8	2.5	2.5	NUM
fnp-3326	190	9	%	%	NOUN
fnp-3326	190	10	constant	constant	ADJ
fnp-3326	190	11	chronic	chronic	ADJ
fnp-3326	190	12	dss	dss	NOUN
fnp-3326	190	13	dose	dose	NOUN
fnp-3326	190	14	presented	present	VERB
fnp-3326	190	15	on	on	ADP
fnp-3326	190	16	average	average	ADJ
fnp-3326	190	17	with	with	ADP
fnp-3326	190	18	a	a	DET
fnp-3326	190	19	slightly	slightly	ADV
fnp-3326	190	20	but	but	CCONJ
fnp-3326	190	21	robust	robust	ADJ
fnp-3326	190	22	increased	increase	VERB
fnp-3326	190	23	percent	percent	NOUN
fnp-3326	190	24	area	area	NOUN
fnp-3326	190	25	of	of	ADP
fnp-3326	190	26	αsyn	αsyn	ADJ
fnp-3326	190	27	inclusions	inclusion	NOUN
fnp-3326	190	28	compared	compare	VERB
fnp-3326	190	29	with	with	ADP
fnp-3326	190	30	the	the	DET
fnp-3326	190	31	6	6	NUM
fnp-3326	190	32	-	-	PUNCT
fnp-3326	190	33	month	month	NOUN
fnp-3326	190	34	-	-	PUNCT
fnp-3326	190	35	old	old	ADJ
fnp-3326	190	36	mice	mouse	NOUN
fnp-3326	190	37	that	that	PRON
fnp-3326	190	38	were	be	AUX
fnp-3326	190	39	on	on	ADP
fnp-3326	190	40	1	1	NUM
fnp-3326	190	41	%	%	NOUN
fnp-3326	190	42	dss	dss	NOUN
fnp-3326	190	43	(	(	PUNCT
fnp-3326	190	44	fig	fig	NOUN
fnp-3326	190	45	.	.	PUNCT
fnp-3326	190	46	2a	2a	NUM
fnp-3326	190	47	)	)	PUNCT
fnp-3326	190	48	.	.	PUNCT
fnp-3326	191	1	together	together	ADV
fnp-3326	191	2	,	,	PUNCT
fnp-3326	191	3	this	this	PRON
fnp-3326	191	4	demonstrated	demonstrate	VERB
fnp-3326	191	5	that	that	SCONJ
fnp-3326	191	6	different	different	ADJ
fnp-3326	191	7	dss	dss	NOUN
fnp-3326	191	8	paradigms	paradigm	NOUN
fnp-3326	191	9	can	can	AUX
fnp-3326	191	10	be	be	AUX
fnp-3326	191	11	established	establish	VERB
fnp-3326	191	12	in	in	ADP
fnp-3326	191	13	(	(	PUNCT
fnp-3326	191	14	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	191	15	transgenic	transgenic	NOUN
fnp-3326	191	16	mice	mouse	NOUN
fnp-3326	191	17	and	and	CCONJ
fnp-3326	191	18	that	that	SCONJ
fnp-3326	191	19	different	different	ADJ
fnp-3326	191	20	dss	dss	NOUN
fnp-3326	191	21	paradigms	paradigm	NOUN
fnp-3326	191	22	can	can	AUX
fnp-3326	191	23	induce	induce	VERB
fnp-3326	191	24	robust	robust	ADJ
fnp-3326	191	25	elevation	elevation	NOUN
fnp-3326	191	26	of	of	ADP
fnp-3326	191	27	αsyn	αsyn	ADJ
fnp-3326	191	28	inclusions	inclusion	NOUN
fnp-3326	191	29	.	.	PUNCT
fnp-3326	192	1	this	this	DET
fnp-3326	192	2	first	first	ADJ
fnp-3326	192	3	experiment	experiment	NOUN
fnp-3326	192	4	also	also	ADV
fnp-3326	192	5	provided	provide	VERB
fnp-3326	192	6	us	we	PRON
fnp-3326	192	7	with	with	ADP
fnp-3326	192	8	data	datum	NOUN
fnp-3326	192	9	points	point	NOUN
fnp-3326	192	10	to	to	PART
fnp-3326	192	11	estimate	estimate	VERB
fnp-3326	192	12	a	a	DET
fnp-3326	192	13	potential	potential	ADJ
fnp-3326	192	14	effect	effect	NOUN
fnp-3326	192	15	size	size	NOUN
fnp-3326	192	16	for	for	ADP
fnp-3326	192	17	triggering	trigger	VERB
fnp-3326	192	18	αsyn	αsyn	ADJ
fnp-3326	192	19	inclusions	inclusion	NOUN
fnp-3326	192	20	in	in	ADP
fnp-3326	192	21	the	the	DET
fnp-3326	192	22	different	different	ADJ
fnp-3326	192	23	dss	dss	NOUN
fnp-3326	192	24	paradigms	paradigm	VERB
fnp-3326	192	25	.	.	PUNCT
fnp-3326	193	1	we	we	PRON
fnp-3326	193	2	observed	observe	VERB
fnp-3326	193	3	that	that	SCONJ
fnp-3326	193	4	the	the	DET
fnp-3326	193	5	younger	young	ADJ
fnp-3326	193	6	(	(	PUNCT
fnp-3326	193	7	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	193	8	transgenic	transgenic	NOUN
fnp-3326	193	9	mice	mouse	NOUN
fnp-3326	193	10	showed	show	VERB
fnp-3326	193	11	a	a	DET
fnp-3326	193	12	robust	robust	ADJ
fnp-3326	193	13	increase	increase	NOUN
fnp-3326	193	14	in	in	ADP
fnp-3326	193	15	αsyn	αsyn	ADJ
fnp-3326	193	16	inclusions	inclusion	NOUN
fnp-3326	193	17	and	and	CCONJ
fnp-3326	193	18	better	well	ADJ
fnp-3326	193	19	signal	signal	VERB
fnp-3326	193	20	-	-	PUNCT
fnp-3326	193	21	to	to	ADP
fnp-3326	193	22	-	-	PUNCT
fnp-3326	193	23	noise	noise	NOUN
fnp-3326	193	24	conditions	condition	NOUN
fnp-3326	193	25	of	of	ADP
fnp-3326	193	26	the	the	DET
fnp-3326	193	27	autofluorescent	autofluorescent	ADJ
fnp-3326	193	28	colonic	colonic	ADJ
fnp-3326	193	29	tissue	tissue	NOUN
fnp-3326	193	30	than	than	ADP
fnp-3326	193	31	the	the	DET
fnp-3326	193	32	older	old	ADJ
fnp-3326	193	33	ones	one	NOUN
fnp-3326	193	34	,	,	PUNCT
fnp-3326	193	35	experiments	experiment	NOUN
fnp-3326	193	36	were	be	AUX
fnp-3326	193	37	henceforth	henceforth	ADV
fnp-3326	193	38	continued	continue	VERB
fnp-3326	193	39	with	with	ADP
fnp-3326	193	40	mice	mouse	NOUN
fnp-3326	193	41	of	of	ADP
fnp-3326	193	42	the	the	DET
fnp-3326	193	43	younger	young	ADJ
fnp-3326	193	44	age	age	NOUN
fnp-3326	193	45	.	.	PUNCT
fnp-3326	194	1	in	in	ADP
fnp-3326	194	2	this	this	DET
fnp-3326	194	3	initial	initial	ADJ
fnp-3326	194	4	experiment	experiment	NOUN
fnp-3326	194	5	,	,	PUNCT
fnp-3326	194	6	it	it	PRON
fnp-3326	194	7	was	be	AUX
fnp-3326	194	8	also	also	ADV
fnp-3326	194	9	interesting	interesting	ADJ
fnp-3326	194	10	to	to	PART
fnp-3326	194	11	observe	observe	VERB
fnp-3326	194	12	that	that	SCONJ
fnp-3326	194	13	(	(	PUNCT
fnp-3326	194	14	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	194	15	transgenic	transgenic	NOUN
fnp-3326	194	16	mice	mouse	NOUN
fnp-3326	194	17	exposed	expose	VERB
fnp-3326	194	18	to	to	AUX
fnp-3326	194	19	acute	acute	VERB
fnp-3326	194	20	2.5	2.5	NUM
fnp-3326	194	21	%	%	NOUN
fnp-3326	194	22	dss	dss	NOUN
fnp-3326	194	23	colitis	colitis	NOUN
fnp-3326	194	24	presented	present	VERB
fnp-3326	194	25	with	with	ADP
fnp-3326	194	26	several	several	ADJ
fnp-3326	194	27	αsyn	αsyn	NOUN
fnp-3326	194	28	-	-	PUNCT
fnp-3326	194	29	positive	positive	ADJ
fnp-3326	194	30	cells	cell	NOUN
fnp-3326	194	31	with	with	ADP
fnp-3326	194	32	a	a	DET
fnp-3326	194	33	morphology	morphology	NOUN
fnp-3326	194	34	consistent	consistent	ADJ
fnp-3326	194	35	with	with	ADP
fnp-3326	194	36	them	they	PRON
fnp-3326	194	37	being	be	AUX
fnp-3326	194	38	infiltrating	infiltrate	VERB
fnp-3326	194	39	leucocytes	leucocyte	NOUN
fnp-3326	194	40	,	,	PUNCT
fnp-3326	194	41	which	which	PRON
fnp-3326	194	42	was	be	AUX
fnp-3326	194	43	confirmed	confirm	VERB
fnp-3326	194	44	by	by	ADP
fnp-3326	194	45	an	an	DET
fnp-3326	194	46	iba-1	iba-1	PUNCT
fnp-3326	194	47	co	co	NOUN
fnp-3326	194	48	-	-	ADJ
fnp-3326	194	49	staining	staining	ADJ
fnp-3326	194	50	(	(	PUNCT
fnp-3326	194	51	suppl	suppl	PROPN
fnp-3326	194	52	.	.	PUNCT
fnp-3326	194	53	fig	fig	NOUN
fnp-3326	194	54	.	.	PUNCT
fnp-3326	195	1	2	2	NUM
fnp-3326	195	2	)	)	PUNCT
fnp-3326	195	3	.	.	PUNCT
fnp-3326	196	1	this	this	DET
fnp-3326	196	2	finding	finding	NOUN
fnp-3326	196	3	was	be	AUX
fnp-3326	196	4	relevant	relevant	ADJ
fnp-3326	196	5	for	for	ADP
fnp-3326	196	6	the	the	DET
fnp-3326	196	7	quantification	quantification	NOUN
fnp-3326	196	8	of	of	ADP
fnp-3326	196	9	αsyn	αsyn	ADJ
fnp-3326	196	10	inclusions	inclusion	NOUN
fnp-3326	196	11	in	in	ADP
fnp-3326	196	12	the	the	DET
fnp-3326	196	13	myenteric	myenteric	ADJ
fnp-3326	196	14	and	and	CCONJ
fnp-3326	196	15	submucosal	submucosal	NOUN
fnp-3326	196	16	plexus	plexus	NOUN
fnp-3326	196	17	,	,	PUNCT
fnp-3326	196	18	i.e.	i.e.	X
fnp-3326	196	19	,	,	PUNCT
fnp-3326	196	20	such	such	ADJ
fnp-3326	196	21	features	feature	NOUN
fnp-3326	196	22	were	be	AUX
fnp-3326	196	23	excluded	exclude	VERB
fnp-3326	196	24	from	from	ADP
fnp-3326	196	25	the	the	DET
fnp-3326	196	26	quantification	quantification	NOUN
fnp-3326	196	27	process	process	NOUN
fnp-3326	196	28	.	.	PUNCT
fnp-3326	197	1	fig	fig	NOUN
fnp-3326	197	2	.	.	PUNCT
fnp-3326	198	1	2	2	NUM
fnp-3326	198	2	experimental	experimental	ADJ
fnp-3326	198	3	dss	dss	NOUN
fnp-3326	198	4	colitis	colitis	NOUN
fnp-3326	198	5	severity	severity	NOUN
fnp-3326	198	6	and	and	CCONJ
fnp-3326	198	7	duration	duration	NOUN
fnp-3326	198	8	-	-	PUNCT
fnp-3326	198	9	dependent	dependent	ADJ
fnp-3326	198	10	aggravation	aggravation	NOUN
fnp-3326	198	11	of	of	ADP
fnp-3326	198	12	accumulation	accumulation	NOUN
fnp-3326	198	13	of	of	ADP
fnp-3326	198	14	αsyn	αsyn	ADJ
fnp-3326	198	15	inclusions	inclusion	NOUN
fnp-3326	198	16	in	in	ADP
fnp-3326	198	17	the	the	DET
fnp-3326	198	18	colonic	colonic	ADJ
fnp-3326	198	19	submucosal	submucosal	NOUN
fnp-3326	198	20	plexus	plexus	NOUN
fnp-3326	198	21	of	of	ADP
fnp-3326	198	22	hemizygous	hemizygous	ADJ
fnp-3326	198	23	(	(	PUNCT
fnp-3326	198	24	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	198	25	transgenic	transgenic	NOUN
fnp-3326	198	26	and	and	CCONJ
fnp-3326	198	27	wild	wild	ADJ
fnp-3326	198	28	type	type	NOUN
fnp-3326	198	29	mice	mouse	NOUN
fnp-3326	198	30	.	.	PUNCT
fnp-3326	199	1	a	a	DET
fnp-3326	199	2	administration	administration	NOUN
fnp-3326	199	3	of	of	ADP
fnp-3326	199	4	dss	dss	NOUN
fnp-3326	199	5	in	in	ADP
fnp-3326	199	6	drinking	drinking	NOUN
fnp-3326	199	7	water	water	NOUN
fnp-3326	199	8	induced	induce	VERB
fnp-3326	199	9	a	a	DET
fnp-3326	199	10	robust	robust	ADJ
fnp-3326	199	11	increase	increase	NOUN
fnp-3326	199	12	of	of	ADP
fnp-3326	199	13	leukocyte	leukocyte	NOUN
fnp-3326	199	14	infiltration	infiltration	NOUN
fnp-3326	199	15	in	in	ADP
fnp-3326	199	16	the	the	DET
fnp-3326	199	17	acute	acute	NOUN
fnp-3326	199	18	(	(	PUNCT
fnp-3326	199	19	1	1	NUM
fnp-3326	199	20	%	%	NOUN
fnp-3326	199	21	or	or	CCONJ
fnp-3326	199	22	2.5	2.5	NUM
fnp-3326	199	23	%	%	NOUN
fnp-3326	199	24	dss	dss	NOUN
fnp-3326	199	25	for	for	ADP
fnp-3326	199	26	5	5	NUM
fnp-3326	199	27	days	day	NOUN
fnp-3326	199	28	followed	follow	VERB
fnp-3326	199	29	by	by	ADP
fnp-3326	199	30	2	2	NUM
fnp-3326	199	31	days	day	NOUN
fnp-3326	199	32	of	of	ADP
fnp-3326	199	33	normal	normal	ADJ
fnp-3326	199	34	drinking	drinking	NOUN
fnp-3326	199	35	water	water	NOUN
fnp-3326	199	36	;	;	PUNCT
fnp-3326	199	37	one	one	NUM
fnp-3326	199	38	group	group	NOUN
fnp-3326	199	39	was	be	AUX
fnp-3326	199	40	kept	keep	VERB
fnp-3326	199	41	on	on	ADP
fnp-3326	199	42	normal	normal	ADJ
fnp-3326	199	43	drinking	drinking	NOUN
fnp-3326	199	44	water	water	NOUN
fnp-3326	199	45	)	)	PUNCT
fnp-3326	199	46	and	and	CCONJ
fnp-3326	199	47	chronic	chronic	ADJ
fnp-3326	199	48	constant	constant	ADJ
fnp-3326	199	49	dss	dss	NOUN
fnp-3326	199	50	dose	dose	NOUN
fnp-3326	199	51	(	(	PUNCT
fnp-3326	199	52	1	1	NUM
fnp-3326	199	53	%	%	NOUN
fnp-3326	199	54	or	or	CCONJ
fnp-3326	199	55	2.5	2.5	NUM
fnp-3326	199	56	%	%	NOUN
fnp-3326	199	57	alternating	alternate	VERB
fnp-3326	199	58	with	with	ADP
fnp-3326	199	59	normal	normal	ADJ
fnp-3326	199	60	drinking	drinking	NOUN
fnp-3326	199	61	water	water	NOUN
fnp-3326	199	62	)	)	PUNCT
fnp-3326	199	63	paradigm	paradigm	NOUN
fnp-3326	199	64	in	in	ADP
fnp-3326	199	65	hemizygous	hemizygous	ADJ
fnp-3326	199	66	(	(	PUNCT
fnp-3326	199	67	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	199	68	transgenic	transgenic	NOUN
fnp-3326	199	69	mice	mouse	NOUN
fnp-3326	199	70	.	.	PUNCT
fnp-3326	200	1	the	the	DET
fnp-3326	200	2	highest	high	ADJ
fnp-3326	200	3	acute	acute	NOUN
fnp-3326	200	4	dose	dose	NOUN
fnp-3326	200	5	(	(	PUNCT
fnp-3326	200	6	2.5	2.5	NUM
fnp-3326	200	7	%	%	NOUN
fnp-3326	200	8	)	)	PUNCT
fnp-3326	200	9	and	and	CCONJ
fnp-3326	200	10	the	the	DET
fnp-3326	200	11	two	two	NUM
fnp-3326	200	12	constant	constant	ADJ
fnp-3326	200	13	chronic	chronic	ADJ
fnp-3326	200	14	doses	dose	NOUN
fnp-3326	200	15	led	lead	VERB
fnp-3326	200	16	to	to	ADP
fnp-3326	200	17	a	a	DET
fnp-3326	200	18	very	very	ADV
fnp-3326	200	19	robust	robust	ADJ
fnp-3326	200	20	increase	increase	NOUN
fnp-3326	200	21	of	of	ADP
fnp-3326	200	22	αsyn	αsyn	ADJ
fnp-3326	200	23	inclusions	inclusion	NOUN
fnp-3326	200	24	in	in	ADP
fnp-3326	200	25	the	the	DET
fnp-3326	200	26	submucosal	submucosal	NOUN
fnp-3326	200	27	plexus	plexus	NOUN
fnp-3326	200	28	(	(	PUNCT
fnp-3326	200	29	stereological	stereological	ADJ
fnp-3326	200	30	quantification	quantification	NOUN
fnp-3326	200	31	of	of	ADP
fnp-3326	200	32	αsyn	αsyn	ADJ
fnp-3326	200	33	inclusions	inclusion	NOUN
fnp-3326	200	34	in	in	ADP
fnp-3326	200	35	the	the	DET
fnp-3326	200	36	submucosal	submucosal	NOUN
fnp-3326	200	37	plexus	plexus	NOUN
fnp-3326	200	38	of	of	ADP
fnp-3326	200	39	all	all	PRON
fnp-3326	200	40	3and	3and	NUM
fnp-3326	200	41	6	6	NUM
fnp-3326	200	42	-	-	PUNCT
fnp-3326	200	43	month	month	NOUN
fnp-3326	200	44	-	-	PUNCT
fnp-3326	200	45	old	old	ADJ
fnp-3326	200	46	hemizygous	hemizygous	ADJ
fnp-3326	200	47	(	(	PUNCT
fnp-3326	200	48	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	200	49	transgenic	transgenic	NOUN
fnp-3326	200	50	mice	mouse	NOUN
fnp-3326	200	51	;	;	PUNCT
fnp-3326	200	52	n	n	NOUN
fnp-3326	200	53	=	=	SYM
fnp-3326	200	54	5	5	NUM
fnp-3326	200	55	-	-	SYM
fnp-3326	200	56	7	7	NUM
fnp-3326	200	57	per	per	ADP
fnp-3326	200	58	group	group	NOUN
fnp-3326	200	59	;	;	PUNCT
fnp-3326	200	60	mean	mean	VERB
fnp-3326	200	61	and	and	CCONJ
fnp-3326	200	62	s.e.m	s.e.m	NOUN
fnp-3326	200	63	.	.	PROPN
fnp-3326	200	64	are	be	AUX
fnp-3326	200	65	shown	show	VERB
fnp-3326	200	66	)	)	PUNCT
fnp-3326	200	67	.	.	PUNCT
fnp-3326	201	1	b	b	X
fnp-3326	201	2	representative	representative	ADJ
fnp-3326	201	3	2d	2d	NOUN
fnp-3326	201	4	z	z	NOUN
fnp-3326	201	5	-	-	PUNCT
fnp-3326	201	6	stacks	stack	NOUN
fnp-3326	201	7	of	of	ADP
fnp-3326	201	8	confocal	confocal	ADJ
fnp-3326	201	9	images	image	NOUN
fnp-3326	201	10	of	of	ADP
fnp-3326	201	11	increasing	increase	VERB
fnp-3326	201	12	abundance	abundance	NOUN
fnp-3326	201	13	of	of	ADP
fnp-3326	201	14	αsyn	αsyn	ADJ
fnp-3326	201	15	inclusions	inclusion	NOUN
fnp-3326	201	16	(	(	PUNCT
fnp-3326	201	17	red	red	ADJ
fnp-3326	201	18	,	,	PUNCT
fnp-3326	201	19	human	human	ADJ
fnp-3326	201	20	-	-	PUNCT
fnp-3326	201	21	αsyn	αsyn	NOUN
fnp-3326	201	22	specific	specific	ADJ
fnp-3326	201	23	monoclonal	monoclonal	NOUN
fnp-3326	201	24	antibody	antibody	NOUN
fnp-3326	201	25	clone	clone	NOUN
fnp-3326	201	26	211	211	NUM
fnp-3326	201	27	)	)	PUNCT
fnp-3326	201	28	in	in	ADP
fnp-3326	201	29	a	a	DET
fnp-3326	201	30	ganglion	ganglion	NOUN
fnp-3326	201	31	of	of	ADP
fnp-3326	201	32	the	the	DET
fnp-3326	201	33	submucosal	submucosal	NOUN
fnp-3326	201	34	plexus	plexus	NOUN
fnp-3326	201	35	(	(	PUNCT
fnp-3326	201	36	green	green	ADJ
fnp-3326	201	37	,	,	PUNCT
fnp-3326	201	38	peripherin	peripherin	NOUN
fnp-3326	201	39	)	)	PUNCT
fnp-3326	201	40	with	with	ADP
fnp-3326	201	41	cellular	cellular	ADJ
fnp-3326	201	42	nuclei	nucleus	NOUN
fnp-3326	201	43	in	in	ADP
fnp-3326	201	44	blue	blue	ADJ
fnp-3326	201	45	(	(	PUNCT
fnp-3326	201	46	dapi	dapi	ADJ
fnp-3326	201	47	)	)	PUNCT
fnp-3326	201	48	in	in	ADP
fnp-3326	201	49	the	the	DET
fnp-3326	201	50	acute	acute	ADJ
fnp-3326	201	51	dss	dss	NOUN
fnp-3326	201	52	paradigm	paradigm	NOUN
fnp-3326	201	53	.	.	PUNCT
fnp-3326	202	1	arrow	arrow	NOUN
fnp-3326	202	2	heads	head	NOUN
fnp-3326	202	3	point	point	VERB
fnp-3326	202	4	to	to	ADP
fnp-3326	202	5	the	the	DET
fnp-3326	202	6	typical	typical	ADJ
fnp-3326	202	7	irregularly	irregularly	ADV
fnp-3326	202	8	sized	sized	ADJ
fnp-3326	202	9	and	and	CCONJ
fnp-3326	202	10	shaped	shape	VERB
fnp-3326	202	11	αsyn	αsyn	ADJ
fnp-3326	202	12	inclusion	inclusion	NOUN
fnp-3326	202	13	bodies	body	NOUN
fnp-3326	202	14	that	that	PRON
fnp-3326	202	15	accumulate	accumulate	VERB
fnp-3326	202	16	in	in	ADP
fnp-3326	202	17	the	the	DET
fnp-3326	202	18	highest	high	ADJ
fnp-3326	202	19	dss	dss	NOUN
fnp-3326	202	20	dose	dose	NOUN
fnp-3326	202	21	.	.	PUNCT
fnp-3326	203	1	scale	scale	NOUN
fnp-3326	203	2	bar	bar	NOUN
fnp-3326	203	3	:	:	PUNCT
fnp-3326	203	4	200	200	NUM
fnp-3326	203	5	µm	µm	NOUN
fnp-3326	203	6	.	.	PUNCT
fnp-3326	204	1	c	c	NOUN
fnp-3326	204	2	overview	overview	NOUN
fnp-3326	204	3	of	of	ADP
fnp-3326	204	4	colonic	colonic	ADJ
fnp-3326	204	5	region	region	NOUN
fnp-3326	204	6	of	of	ADP
fnp-3326	204	7	3	3	NUM
fnp-3326	204	8	-	-	PUNCT
fnp-3326	204	9	month	month	NOUN
fnp-3326	204	10	-	-	PUNCT
fnp-3326	204	11	old	old	ADJ
fnp-3326	204	12	wild	wild	ADJ
fnp-3326	204	13	type	type	NOUN
fnp-3326	204	14	mice	mouse	NOUN
fnp-3326	204	15	exposed	expose	VERB
fnp-3326	204	16	to	to	ADP
fnp-3326	204	17	water	water	NOUN
fnp-3326	204	18	or	or	CCONJ
fnp-3326	204	19	acute	acute	ADJ
fnp-3326	204	20	dss	dss	NOUN
fnp-3326	204	21	(	(	PUNCT
fnp-3326	204	22	5	5	NUM
fnp-3326	204	23	%	%	NOUN
fnp-3326	204	24	)	)	PUNCT
fnp-3326	204	25	with	with	ADP
fnp-3326	204	26	immunofluorescence	immunofluorescence	NOUN
fnp-3326	204	27	analysis	analysis	NOUN
fnp-3326	204	28	of	of	ADP
fnp-3326	204	29	murine	murine	ADJ
fnp-3326	204	30	αsyn	αsyn	ADJ
fnp-3326	204	31	load	load	NOUN
fnp-3326	204	32	in	in	ADP
fnp-3326	204	33	the	the	DET
fnp-3326	204	34	colon	colon	NOUN
fnp-3326	204	35	performed	perform	VERB
fnp-3326	204	36	immediately	immediately	ADV
fnp-3326	204	37	after	after	ADP
fnp-3326	204	38	colitis	colitis	NOUN
fnp-3326	204	39	.	.	PUNCT
fnp-3326	205	1	white	white	PROPN
fnp-3326	205	2	dotted	dotted	ADJ
fnp-3326	205	3	rectangles	rectangle	NOUN
fnp-3326	205	4	in	in	ADP
fnp-3326	205	5	the	the	DET
fnp-3326	205	6	top	top	NOUN
fnp-3326	205	7	row	row	NOUN
fnp-3326	205	8	indicate	indicate	VERB
fnp-3326	205	9	the	the	DET
fnp-3326	205	10	area	area	NOUN
fnp-3326	205	11	that	that	PRON
fnp-3326	205	12	was	be	AUX
fnp-3326	205	13	zoomed	zoom	VERB
fnp-3326	205	14	-	-	PUNCT
fnp-3326	205	15	in	in	ADV
fnp-3326	205	16	in	in	ADP
fnp-3326	205	17	the	the	DET
fnp-3326	205	18	lower	low	ADJ
fnp-3326	205	19	panels	panel	NOUN
fnp-3326	205	20	.	.	PUNCT
fnp-3326	206	1	in	in	ADP
fnp-3326	206	2	the	the	DET
fnp-3326	206	3	zoom	zoom	NOUN
fnp-3326	206	4	-	-	PUNCT
fnp-3326	206	5	ins	in	NOUN
fnp-3326	206	6	we	we	PRON
fnp-3326	206	7	show	show	VERB
fnp-3326	206	8	representative	representative	ADJ
fnp-3326	206	9	images	image	NOUN
fnp-3326	206	10	of	of	ADP
fnp-3326	206	11	dapi	dapi	NOUN
fnp-3326	206	12	and	and	CCONJ
fnp-3326	206	13	αsyn	αsyn	PROPN
fnp-3326	206	14	(	(	PUNCT
fnp-3326	206	15	red	red	ADJ
fnp-3326	206	16	,	,	PUNCT
fnp-3326	206	17	rodent	rodent	ADJ
fnp-3326	206	18	αsyn	αsyn	ADJ
fnp-3326	206	19	cross	cross	ADJ
fnp-3326	206	20	-	-	ADJ
fnp-3326	206	21	reactive	reactive	ADJ
fnp-3326	206	22	monoclonal	monoclonal	NOUN
fnp-3326	206	23	antibody	antibody	NOUN
fnp-3326	206	24	syn1	syn1	NOUN
fnp-3326	206	25	/	/	SYM
fnp-3326	206	26	clone	clone	NOUN
fnp-3326	206	27	42	42	NUM
fnp-3326	206	28	)	)	PUNCT
fnp-3326	206	29	inclusions	inclusion	NOUN
fnp-3326	206	30	with	with	ADP
fnp-3326	206	31	and	and	CCONJ
fnp-3326	206	32	without	without	ADP
fnp-3326	206	33	the	the	DET
fnp-3326	206	34	peripherin	peripherin	NOUN
fnp-3326	206	35	channel	channel	NOUN
fnp-3326	206	36	(	(	PUNCT
fnp-3326	206	37	green	green	NOUN
fnp-3326	206	38	)	)	PUNCT
fnp-3326	206	39	.	.	PUNCT
fnp-3326	207	1	the	the	DET
fnp-3326	207	2	white	white	PROPN
fnp-3326	207	3	dotted	dot	VERB
fnp-3326	207	4	circled	circle	VERB
fnp-3326	207	5	area	area	NOUN
fnp-3326	207	6	illustrates	illustrate	VERB
fnp-3326	207	7	the	the	DET
fnp-3326	207	8	peripherin	peripherin	NOUN
fnp-3326	207	9	-	-	PUNCT
fnp-3326	207	10	positive	positive	ADJ
fnp-3326	207	11	area	area	NOUN
fnp-3326	207	12	that	that	PRON
fnp-3326	207	13	was	be	AUX
fnp-3326	207	14	analyzed	analyze	VERB
fnp-3326	207	15	for	for	ADP
fnp-3326	207	16	αsyn	αsyn	ADJ
fnp-3326	207	17	inclusion	inclusion	NOUN
fnp-3326	207	18	bodies	body	NOUN
fnp-3326	207	19	(	(	PUNCT
fnp-3326	207	20	arrow	arrow	NOUN
fnp-3326	207	21	heads	head	NOUN
fnp-3326	207	22	in	in	ADP
fnp-3326	207	23	bottom	bottom	ADJ
fnp-3326	207	24	row	row	NOUN
fnp-3326	207	25	)	)	PUNCT
fnp-3326	207	26	.	.	PUNCT
fnp-3326	208	1	scale	scale	NOUN
fnp-3326	208	2	bar	bar	NOUN
fnp-3326	208	3	for	for	ADP
fnp-3326	208	4	the	the	DET
fnp-3326	208	5	lower	low	ADJ
fnp-3326	208	6	three	three	NUM
fnp-3326	208	7	panels	panel	NOUN
fnp-3326	208	8	:	:	PUNCT
fnp-3326	208	9	200	200	NUM
fnp-3326	208	10	μm	μm	NOUN
fnp-3326	208	11	.	.	PUNCT
fnp-3326	209	1	d	d	X
fnp-3326	209	2	stereological	stereological	ADJ
fnp-3326	209	3	quantification	quantification	NOUN
fnp-3326	209	4	of	of	ADP
fnp-3326	209	5	murine	murine	ADJ
fnp-3326	209	6	αsyn	αsyn	ADJ
fnp-3326	209	7	inclusions	inclusion	NOUN
fnp-3326	209	8	in	in	ADP
fnp-3326	209	9	the	the	DET
fnp-3326	209	10	submucosal	submucosal	NOUN
fnp-3326	209	11	plexus	plexus	NOUN
fnp-3326	209	12	of	of	ADP
fnp-3326	209	13	wild	wild	ADJ
fnp-3326	209	14	type	type	NOUN
fnp-3326	209	15	mice	mouse	NOUN
fnp-3326	209	16	right	right	ADV
fnp-3326	209	17	after	after	ADP
fnp-3326	209	18	acute	acute	ADJ
fnp-3326	209	19	dss	dss	NOUN
fnp-3326	209	20	colitis	colitis	NOUN
fnp-3326	209	21	(	(	PUNCT
fnp-3326	209	22	n	n	NOUN
fnp-3326	209	23	=	=	SYM
fnp-3326	209	24	5	5	NUM
fnp-3326	209	25	per	per	ADP
fnp-3326	209	26	group	group	NOUN
fnp-3326	209	27	)	)	PUNCT
fnp-3326	209	28	.	.	PUNCT
fnp-3326	210	1	note	note	VERB
fnp-3326	210	2	the	the	DET
fnp-3326	210	3	regularly	regularly	ADV
fnp-3326	210	4	arranged	arrange	VERB
fnp-3326	210	5	and	and	CCONJ
fnp-3326	210	6	smoothly	smoothly	ADV
fnp-3326	210	7	distributed	distribute	VERB
fnp-3326	210	8	immunoreactivity	immunoreactivity	NOUN
fnp-3326	210	9	for	for	ADP
fnp-3326	210	10	the	the	DET
fnp-3326	210	11	physiological	physiological	ADJ
fnp-3326	210	12	αsyn	αsyn	NOUN
fnp-3326	210	13	with	with	ADP
fnp-3326	210	14	barely	barely	ADV
fnp-3326	210	15	any	any	DET
fnp-3326	210	16	inclusion	inclusion	NOUN
fnp-3326	210	17	bodies	body	NOUN
fnp-3326	210	18	in	in	ADP
fnp-3326	210	19	the	the	DET
fnp-3326	210	20	intact	intact	ADJ
fnp-3326	210	21	enteric	enteric	ADJ
fnp-3326	210	22	nerves	nerve	NOUN
fnp-3326	210	23	of	of	ADP
fnp-3326	210	24	the	the	DET
fnp-3326	210	25	water	water	NOUN
fnp-3326	210	26	group	group	NOUN
fnp-3326	210	27	.	.	PUNCT
fnp-3326	211	1	for	for	ADP
fnp-3326	211	2	both	both	DET
fnp-3326	211	3	panels	panel	NOUN
fnp-3326	211	4	(	(	PUNCT
fnp-3326	211	5	a	a	X
fnp-3326	211	6	)	)	PUNCT
fnp-3326	211	7	and	and	CCONJ
fnp-3326	211	8	(	(	PUNCT
fnp-3326	211	9	d	d	NOUN
fnp-3326	211	10	)	)	PUNCT
fnp-3326	211	11	,	,	PUNCT
fnp-3326	211	12	statistical	statistical	ADJ
fnp-3326	211	13	analysis	analysis	NOUN
fnp-3326	211	14	for	for	ADP
fnp-3326	211	15	αsyn	αsyn	ADJ
fnp-3326	211	16	accumulation	accumulation	NOUN
fnp-3326	211	17	was	be	AUX
fnp-3326	211	18	omitted	omit	VERB
fnp-3326	211	19	as	as	ADP
fnp-3326	211	20	the	the	DET
fnp-3326	211	21	noticeable	noticeable	ADJ
fnp-3326	211	22	and	and	CCONJ
fnp-3326	211	23	very	very	ADV
fnp-3326	211	24	robust	robust	ADJ
fnp-3326	211	25	differences	difference	NOUN
fnp-3326	211	26	between	between	ADP
fnp-3326	211	27	the	the	DET
fnp-3326	211	28	means	mean	NOUN
fnp-3326	211	29	are	be	AUX
fnp-3326	211	30	self	self	NOUN
fnp-3326	211	31	-	-	PUNCT
fnp-3326	211	32	evident	evident	ADJ
fnp-3326	211	33	(	(	PUNCT
fnp-3326	211	34	error	error	NOUN
fnp-3326	211	35	bars	bar	NOUN
fnp-3326	211	36	indicate	indicate	VERB
fnp-3326	211	37	standard	standard	ADJ
fnp-3326	211	38	error	error	NOUN
fnp-3326	211	39	of	of	ADP
fnp-3326	211	40	the	the	DET
fnp-3326	211	41	mean	mean	NOUN
fnp-3326	211	42	)	)	PUNCT
fnp-3326	211	43	and	and	CCONJ
fnp-3326	211	44	an	an	DET
fnp-3326	211	45	indication	indication	NOUN
fnp-3326	211	46	for	for	ADP
fnp-3326	211	47	an	an	DET
fnp-3326	211	48	estimation	estimation	NOUN
fnp-3326	211	49	for	for	ADP
fnp-3326	211	50	significance	significance	NOUN
fnp-3326	211	51	would	would	AUX
fnp-3326	211	52	be	be	AUX
fnp-3326	211	53	irrelevant	irrelevant	ADJ
fnp-3326	211	54	.	.	PUNCT
fnp-3326	212	1	wild	wild	ADJ
fnp-3326	212	2	type	type	NOUN
fnp-3326	212	3	mice	mouse	NOUN
fnp-3326	212	4	also	also	ADV
fnp-3326	212	5	express	express	VERB
fnp-3326	212	6	endogenous	endogenous	ADJ
fnp-3326	212	7	αsyn	αsyn	NOUN
fnp-3326	212	8	in	in	ADP
fnp-3326	212	9	innervated	innervated	ADJ
fnp-3326	212	10	organs	organ	NOUN
fnp-3326	212	11	,	,	PUNCT
fnp-3326	212	12	but	but	CCONJ
fnp-3326	212	13	at	at	ADP
fnp-3326	212	14	much	much	ADV
fnp-3326	212	15	lower	low	ADJ
fnp-3326	212	16	levels	level	NOUN
fnp-3326	212	17	compared	compare	VERB
fnp-3326	212	18	with	with	ADP
fnp-3326	212	19	the	the	DET
fnp-3326	212	20	levels	level	NOUN
fnp-3326	212	21	of	of	ADP
fnp-3326	212	22	human	human	ADJ
fnp-3326	212	23	αsyn	αsyn	NOUN
fnp-3326	212	24	expressed	express	VERB
fnp-3326	212	25	by	by	ADP
fnp-3326	212	26	the	the	DET
fnp-3326	212	27	hemizygous	hemizygous	ADJ
fnp-3326	212	28	(	(	PUNCT
fnp-3326	212	29	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	212	30	transgenic	transgenic	NOUN
fnp-3326	212	31	mice	mouse	NOUN
fnp-3326	212	32	(	(	PUNCT
fnp-3326	212	33	suppl	suppl	PROPN
fnp-3326	212	34	.	.	PUNCT
fnp-3326	212	35	fig	fig	NOUN
fnp-3326	212	36	.	.	PUNCT
fnp-3326	212	37	1	1	NUM
fnp-3326	212	38	)	)	PUNCT
fnp-3326	212	39	.	.	PUNCT
fnp-3326	213	1	to	to	PART
fnp-3326	213	2	confirm	confirm	VERB
fnp-3326	213	3	that	that	SCONJ
fnp-3326	213	4	the	the	DET
fnp-3326	213	5	finding	finding	NOUN
fnp-3326	213	6	in	in	ADP
fnp-3326	213	7	(	(	PUNCT
fnp-3326	213	8	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	213	9	transgenic	transgenic	NOUN
fnp-3326	213	10	mice	mouse	NOUN
fnp-3326	213	11	was	be	AUX
fnp-3326	213	12	independent	independent	ADJ
fnp-3326	213	13	of	of	ADP
fnp-3326	213	14	transgenic	transgenic	NOUN
fnp-3326	213	15	expression	expression	NOUN
fnp-3326	213	16	of	of	ADP
fnp-3326	213	17	human	human	ADJ
fnp-3326	213	18	αsyn	αsyn	NOUN
fnp-3326	213	19	,	,	PUNCT
fnp-3326	213	20	we	we	PRON
fnp-3326	213	21	applied	apply	VERB
fnp-3326	213	22	an	an	DET
fnp-3326	213	23	acute	acute	ADJ
fnp-3326	213	24	5	5	NUM
fnp-3326	213	25	%	%	NOUN
fnp-3326	213	26	dss	dss	NOUN
fnp-3326	213	27	dose	dose	NOUN
fnp-3326	213	28	paradigm	paradigm	NOUN
fnp-3326	213	29	(	(	PUNCT
fnp-3326	213	30	5	5	NUM
fnp-3326	213	31	days	day	NOUN
fnp-3326	213	32	dss	dss	NOUN
fnp-3326	213	33	+	+	CCONJ
fnp-3326	213	34	2	2	NUM
fnp-3326	213	35	days	day	NOUN
fnp-3326	213	36	water	water	NOUN
fnp-3326	213	37	)	)	PUNCT
fnp-3326	213	38	in	in	ADP
fnp-3326	213	39	wild	wild	ADJ
fnp-3326	213	40	type	type	NOUN
fnp-3326	213	41	mice	mouse	NOUN
fnp-3326	213	42	(	(	PUNCT
fnp-3326	213	43	fig	fig	NOUN
fnp-3326	213	44	.	.	PUNCT
fnp-3326	214	1	1c	1c	NOUN
fnp-3326	214	2	)	)	PUNCT
fnp-3326	214	3	.	.	PUNCT
fnp-3326	215	1	we	we	PRON
fnp-3326	215	2	observed	observe	VERB
fnp-3326	215	3	,	,	PUNCT
fnp-3326	215	4	in	in	ADP
fnp-3326	215	5	the	the	DET
fnp-3326	215	6	submucosal	submucosal	NOUN
fnp-3326	215	7	plexus	plexus	NOUN
fnp-3326	215	8	,	,	PUNCT
fnp-3326	215	9	small	small	ADJ
fnp-3326	215	10	inclusion	inclusion	NOUN
fnp-3326	215	11	bodies	body	NOUN
fnp-3326	215	12	of	of	ADP
fnp-3326	215	13	endogenous	endogenous	ADJ
fnp-3326	215	14	murine	murine	ADJ
fnp-3326	215	15	αsyn	αsyn	NOUN
fnp-3326	215	16	(	(	PUNCT
fnp-3326	215	17	detected	detect	VERB
fnp-3326	215	18	by	by	ADP
fnp-3326	215	19	rodent	rodent	ADJ
fnp-3326	215	20	cross	cross	ADJ
fnp-3326	215	21	-	-	ADJ
fnp-3326	215	22	reactive	reactive	ADJ
fnp-3326	215	23	αsyn	αsyn	NOUN
fnp-3326	215	24	-	-	PUNCT
fnp-3326	215	25	specific	specific	ADJ
fnp-3326	215	26	monoclonal	monoclonal	NOUN
fnp-3326	215	27	antibody	antibody	NOUN
fnp-3326	215	28	syn1	syn1	NOUN
fnp-3326	215	29	/	/	SYM
fnp-3326	215	30	clone	clone	NOUN
fnp-3326	215	31	42	42	NUM
fnp-3326	215	32	,	,	PUNCT
fnp-3326	215	33	fig	fig	NOUN
fnp-3326	215	34	.	.	PUNCT
fnp-3326	216	1	2c	2c	NUM
fnp-3326	216	2	,	,	PUNCT
fnp-3326	216	3	d	d	NOUN
fnp-3326	216	4	)	)	PUNCT
fnp-3326	216	5	.	.	PUNCT
fnp-3326	217	1	these	these	DET
fnp-3326	217	2	features	feature	NOUN
fnp-3326	217	3	were	be	AUX
fnp-3326	217	4	close	close	ADJ
fnp-3326	217	5	to	to	ADP
fnp-3326	217	6	undetectable	undetectable	ADJ
fnp-3326	217	7	in	in	ADP
fnp-3326	217	8	the	the	DET
fnp-3326	217	9	water	water	NOUN
fnp-3326	217	10	group	group	NOUN
fnp-3326	217	11	that	that	PRON
fnp-3326	217	12	did	do	AUX
fnp-3326	217	13	not	not	PART
fnp-3326	217	14	experience	experience	VERB
fnp-3326	217	15	experimental	experimental	ADJ
fnp-3326	217	16	colitis	colitis	NOUN
fnp-3326	217	17	.	.	PUNCT
fnp-3326	218	1	a	a	DET
fnp-3326	218	2	separate	separate	ADJ
fnp-3326	218	3	experiment	experiment	NOUN
fnp-3326	218	4	also	also	ADV
fnp-3326	218	5	confirmed	confirm	VERB
fnp-3326	218	6	that	that	SCONJ
fnp-3326	218	7	the	the	DET
fnp-3326	218	8	observed	observed	ADJ
fnp-3326	218	9	effects	effect	NOUN
fnp-3326	218	10	of	of	ADP
fnp-3326	218	11	elevated	elevated	ADJ
fnp-3326	218	12	αsyn	αsyn	ADJ
fnp-3326	218	13	inclusions	inclusion	NOUN
fnp-3326	218	14	following	follow	VERB
fnp-3326	218	15	acute	acute	ADJ
fnp-3326	218	16	dss	dss	NOUN
fnp-3326	218	17	(	(	PUNCT
fnp-3326	218	18	5	5	NUM
fnp-3326	218	19	%	%	NOUN
fnp-3326	218	20	dose	dose	NOUN
fnp-3326	218	21	)	)	PUNCT
fnp-3326	218	22	could	could	AUX
fnp-3326	218	23	not	not	PART
fnp-3326	218	24	be	be	AUX
fnp-3326	218	25	attributed	attribute	VERB
fnp-3326	218	26	to	to	ADP
fnp-3326	218	27	increased	increase	VERB
fnp-3326	218	28	gene	gene	NOUN
fnp-3326	218	29	expression	expression	NOUN
fnp-3326	218	30	of	of	ADP
fnp-3326	218	31	murine	murine	ADJ
fnp-3326	218	32	or	or	CCONJ
fnp-3326	218	33	the	the	DET
fnp-3326	218	34	transgenic	transgenic	NOUN
fnp-3326	218	35	human	human	ADJ
fnp-3326	218	36	αsyn	αsyn	NOUN
fnp-3326	218	37	(	(	PUNCT
fnp-3326	218	38	suppl	suppl	PROPN
fnp-3326	218	39	.	.	PUNCT
fnp-3326	218	40	fig	fig	PROPN
fnp-3326	218	41	.	.	PUNCT
fnp-3326	219	1	3	3	NUM
fnp-3326	219	2	)	)	PUNCT
fnp-3326	219	3	.	.	PUNCT
fnp-3326	220	1	together	together	ADV
fnp-3326	220	2	,	,	PUNCT
fnp-3326	220	3	these	these	DET
fnp-3326	220	4	results	result	NOUN
fnp-3326	220	5	confirmed	confirm	VERB
fnp-3326	220	6	the	the	DET
fnp-3326	220	7	validity	validity	NOUN
fnp-3326	220	8	of	of	ADP
fnp-3326	220	9	this	this	DET
fnp-3326	220	10	experimental	experimental	ADJ
fnp-3326	220	11	ibd	ibd	PROPN
fnp-3326	220	12	paradigm	paradigm	NOUN
fnp-3326	220	13	to	to	PART
fnp-3326	220	14	test	test	VERB
fnp-3326	220	15	the	the	DET
fnp-3326	220	16	effect	effect	NOUN
fnp-3326	220	17	of	of	ADP
fnp-3326	220	18	inflammation	inflammation	NOUN
fnp-3326	220	19	on	on	ADP
fnp-3326	220	20	αsyn	αsyn	ADJ
fnp-3326	220	21	accumulation	accumulation	NOUN
fnp-3326	220	22	in	in	ADP
fnp-3326	220	23	the	the	DET
fnp-3326	220	24	ens	ens	NOUN
fnp-3326	220	25	in	in	ADP
fnp-3326	220	26	wild	wild	ADJ
fnp-3326	220	27	type	type	NOUN
fnp-3326	220	28	and	and	CCONJ
fnp-3326	220	29	(	(	PUNCT
fnp-3326	220	30	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	220	31	transgenic	transgenic	NOUN
fnp-3326	220	32	mice	mouse	NOUN
fnp-3326	220	33	.	.	PUNCT
fnp-3326	221	1	because	because	SCONJ
fnp-3326	221	2	the	the	DET
fnp-3326	221	3	(	(	PUNCT
fnp-3326	221	4	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	221	5	transgenic	transgenic	NOUN
fnp-3326	221	6	mouse	mouse	NOUN
fnp-3326	221	7	model	model	NOUN
fnp-3326	221	8	is	be	AUX
fnp-3326	221	9	well	well	ADV
fnp-3326	221	10	-	-	PUNCT
fnp-3326	221	11	established	establish	VERB
fnp-3326	221	12	to	to	PART
fnp-3326	221	13	analyze	analyze	VERB
fnp-3326	221	14	human	human	ADJ
fnp-3326	221	15	αsyn	αsyn	NOUN
fnp-3326	221	16	-	-	PUNCT
fnp-3326	221	17	related	relate	VERB
fnp-3326	221	18	pathology	pathology	NOUN
fnp-3326	221	19	,	,	PUNCT
fnp-3326	221	20	we	we	PRON
fnp-3326	221	21	focused	focus	VERB
fnp-3326	221	22	for	for	ADP
fnp-3326	221	23	the	the	DET
fnp-3326	221	24	remainder	remainder	NOUN
fnp-3326	221	25	of	of	ADP
fnp-3326	221	26	the	the	DET
fnp-3326	221	27	study	study	NOUN
fnp-3326	221	28	on	on	ADP
fnp-3326	221	29	employing	employ	VERB
fnp-3326	221	30	these	these	DET
fnp-3326	221	31	transgenic	transgenic	ADJ
fnp-3326	221	32	mice	mouse	NOUN
fnp-3326	221	33	.	.	PUNCT
fnp-3326	222	1	colitis	colitis	NOUN
fnp-3326	222	2	induced	induce	VERB
fnp-3326	222	3	by	by	ADP
fnp-3326	222	4	peroral	peroral	ADJ
fnp-3326	222	5	dss	dss	NOUN
fnp-3326	222	6	but	but	CCONJ
fnp-3326	222	7	not	not	PART
fnp-3326	222	8	by	by	ADP
fnp-3326	222	9	intraperitoneal	intraperitoneal	ADJ
fnp-3326	222	10	administration	administration	NOUN
fnp-3326	222	11	of	of	ADP
fnp-3326	222	12	lps	lps	PROPN
fnp-3326	222	13	aggravates	aggravate	VERB
fnp-3326	222	14	αsyn	αsyn	ADJ
fnp-3326	222	15	accumulation	accumulation	NOUN
fnp-3326	222	16	in	in	ADP
fnp-3326	222	17	colonic	colonic	ADJ
fnp-3326	222	18	submucosal	submucosal	NOUN
fnp-3326	222	19	plexus	plexus	NOUN
fnp-3326	222	20	of	of	ADP
fnp-3326	222	21	αsyn	αsyn	ADJ
fnp-3326	222	22	transgenic	transgenic	NOUN
fnp-3326	222	23	mice	mouse	NOUN
fnp-3326	222	24	different	different	ADJ
fnp-3326	222	25	inflammatory	inflammatory	ADJ
fnp-3326	222	26	agents	agent	NOUN
fnp-3326	222	27	induce	induce	VERB
fnp-3326	222	28	different	different	ADJ
fnp-3326	222	29	types	type	NOUN
fnp-3326	222	30	of	of	ADP
fnp-3326	222	31	immune	immune	ADJ
fnp-3326	222	32	stimulation	stimulation	NOUN
fnp-3326	222	33	and	and	CCONJ
fnp-3326	222	34	thus	thus	ADV
fnp-3326	222	35	can	can	AUX
fnp-3326	222	36	influence	influence	VERB
fnp-3326	222	37	the	the	DET
fnp-3326	222	38	phenotype	phenotype	NOUN
fnp-3326	222	39	of	of	ADP
fnp-3326	222	40	experimental	experimental	ADJ
fnp-3326	222	41	colitis	colitis	NOUN
fnp-3326	222	42	.	.	PUNCT
fnp-3326	223	1	a	a	DET
fnp-3326	223	2	well	well	ADV
fnp-3326	223	3	-	-	PUNCT
fnp-3326	223	4	established	establish	VERB
fnp-3326	223	5	experimental	experimental	ADJ
fnp-3326	223	6	immune	immune	ADJ
fnp-3326	223	7	trigger	trigger	NOUN
fnp-3326	223	8	is	be	AUX
fnp-3326	223	9	the	the	DET
fnp-3326	223	10	bacterial	bacterial	ADJ
fnp-3326	223	11	endotoxin	endotoxin	ADJ
fnp-3326	223	12	lps	lps	PROPN
fnp-3326	223	13	.	.	PUNCT
fnp-3326	224	1	in	in	ADP
fnp-3326	224	2	order	order	NOUN
fnp-3326	224	3	to	to	PART
fnp-3326	224	4	explore	explore	VERB
fnp-3326	224	5	the	the	DET
fnp-3326	224	6	effects	effect	NOUN
fnp-3326	224	7	of	of	ADP
fnp-3326	224	8	different	different	ADJ
fnp-3326	224	9	approaches	approach	NOUN
fnp-3326	224	10	to	to	PART
fnp-3326	224	11	induce	induce	VERB
fnp-3326	224	12	inflammation	inflammation	NOUN
fnp-3326	224	13	in	in	ADP
fnp-3326	224	14	or	or	CCONJ
fnp-3326	224	15	nearby	nearby	ADV
fnp-3326	224	16	the	the	DET
fnp-3326	224	17	gut	gut	NOUN
fnp-3326	224	18	in	in	ADP
fnp-3326	224	19	(	(	PUNCT
fnp-3326	224	20	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	224	21	transgenic	transgenic	NOUN
fnp-3326	224	22	mice	mouse	NOUN
fnp-3326	224	23	,	,	PUNCT
fnp-3326	224	24	we	we	PRON
fnp-3326	224	25	compared	compare	VERB
fnp-3326	224	26	the	the	DET
fnp-3326	224	27	outcome	outcome	NOUN
fnp-3326	224	28	of	of	ADP
fnp-3326	224	29	acute	acute	NOUN
fnp-3326	224	30	(	(	PUNCT
fnp-3326	224	31	5	5	NUM
fnp-3326	224	32	days	day	NOUN
fnp-3326	224	33	dss	dss	NOUN
fnp-3326	224	34	+	+	CCONJ
fnp-3326	224	35	2	2	NUM
fnp-3326	224	36	days	day	NOUN
fnp-3326	224	37	normal	normal	ADJ
fnp-3326	224	38	drinking	drinking	NOUN
fnp-3326	224	39	water	water	NOUN
fnp-3326	224	40	)	)	PUNCT
fnp-3326	224	41	5	5	NUM
fnp-3326	224	42	%	%	NOUN
fnp-3326	224	43	dss	dss	NOUN
fnp-3326	224	44	per	per	ADP
fnp-3326	224	45	os	os	NOUN
fnp-3326	224	46	with	with	ADP
fnp-3326	224	47	acute	acute	PROPN
fnp-3326	224	48	0.5	0.5	NUM
fnp-3326	224	49	mg	mg	PROPN
fnp-3326	224	50	/	/	SYM
fnp-3326	224	51	kg	kg	PROPN
fnp-3326	224	52	intraperitoneal	intraperitoneal	PROPN
fnp-3326	224	53	lps	lps	PROPN
fnp-3326	224	54	administration	administration	NOUN
fnp-3326	224	55	(	(	PUNCT
fnp-3326	224	56	fig	fig	NOUN
fnp-3326	224	57	.	.	PUNCT
fnp-3326	225	1	1c	1c	NOUN
fnp-3326	225	2	and	and	CCONJ
fnp-3326	225	3	3	3	NUM
fnp-3326	225	4	)	)	PUNCT
fnp-3326	225	5	.	.	PUNCT
fnp-3326	226	1	to	to	PART
fnp-3326	226	2	maximize	maximize	VERB
fnp-3326	226	3	the	the	DET
fnp-3326	226	4	inflammatory	inflammatory	ADJ
fnp-3326	226	5	response	response	NOUN
fnp-3326	226	6	,	,	PUNCT
fnp-3326	226	7	we	we	PRON
fnp-3326	226	8	administered	administer	VERB
fnp-3326	226	9	both	both	DET
fnp-3326	226	10	dss	dss	NOUN
fnp-3326	226	11	and	and	CCONJ
fnp-3326	226	12	lps	lps	PROPN
fnp-3326	226	13	at	at	ADP
fnp-3326	226	14	relatively	relatively	ADV
fnp-3326	226	15	high	high	ADJ
fnp-3326	226	16	doses	dose	NOUN
fnp-3326	226	17	.	.	PUNCT
fnp-3326	227	1	at	at	ADP
fnp-3326	227	2	day	day	NOUN
fnp-3326	227	3	7	7	NUM
fnp-3326	227	4	,	,	PUNCT
fnp-3326	227	5	both	both	DET
fnp-3326	227	6	agents	agent	NOUN
fnp-3326	227	7	had	have	AUX
fnp-3326	227	8	induced	induce	VERB
fnp-3326	227	9	variable	variable	ADJ
fnp-3326	227	10	degrees	degree	NOUN
fnp-3326	227	11	of	of	ADP
fnp-3326	227	12	leukocyte	leukocyte	NOUN
fnp-3326	227	13	infiltration	infiltration	NOUN
fnp-3326	227	14	in	in	ADP
fnp-3326	227	15	the	the	DET
fnp-3326	227	16	submucosa	submucosa	NOUN
fnp-3326	227	17	of	of	ADP
fnp-3326	227	18	the	the	DET
fnp-3326	227	19	colon	colon	NOUN
fnp-3326	227	20	while	while	SCONJ
fnp-3326	227	21	a	a	DET
fnp-3326	227	22	marked	mark	VERB
fnp-3326	227	23	destruction	destruction	NOUN
fnp-3326	227	24	of	of	ADP
fnp-3326	227	25	the	the	DET
fnp-3326	227	26	mucosa	mucosa	NOUN
fnp-3326	227	27	was	be	AUX
fnp-3326	227	28	induced	induce	VERB
fnp-3326	227	29	when	when	SCONJ
fnp-3326	227	30	giving	give	VERB
fnp-3326	227	31	only	only	ADV
fnp-3326	227	32	dss	dss	NOUN
fnp-3326	227	33	(	(	PUNCT
fnp-3326	227	34	fig	fig	NOUN
fnp-3326	227	35	.	.	PUNCT
fnp-3326	228	1	1d	1d	NUM
fnp-3326	228	2	)	)	PUNCT
fnp-3326	228	3	.	.	PUNCT
fnp-3326	229	1	as	as	ADP
fnp-3326	229	2	before	before	ADV
fnp-3326	229	3	,	,	PUNCT
fnp-3326	229	4	the	the	DET
fnp-3326	229	5	dss	dss	NOUN
fnp-3326	229	6	-	-	PUNCT
fnp-3326	229	7	exposed	expose	VERB
fnp-3326	229	8	mice	mouse	NOUN
fnp-3326	229	9	presented	present	VERB
fnp-3326	229	10	with	with	ADP
fnp-3326	229	11	increased	increase	VERB
fnp-3326	229	12	accumulation	accumulation	NOUN
fnp-3326	229	13	of	of	ADP
fnp-3326	229	14	αsyn	αsyn	NOUN
fnp-3326	229	15	in	in	ADP
fnp-3326	229	16	the	the	DET
fnp-3326	229	17	ganglia	ganglia	NOUN
fnp-3326	229	18	of	of	ADP
fnp-3326	229	19	the	the	DET
fnp-3326	229	20	submucosal	submucosal	NOUN
fnp-3326	229	21	plexus	plexus	NOUN
fnp-3326	229	22	(	(	PUNCT
fnp-3326	229	23	fig	fig	NOUN
fnp-3326	229	24	.	.	PUNCT
fnp-3326	230	1	3a	3a	NUM
fnp-3326	230	2	)	)	PUNCT
fnp-3326	230	3	.	.	PUNCT
fnp-3326	231	1	in	in	ADP
fnp-3326	231	2	contrast	contrast	NOUN
fnp-3326	231	3	,	,	PUNCT
fnp-3326	231	4	we	we	PRON
fnp-3326	231	5	detected	detect	VERB
fnp-3326	231	6	no	no	DET
fnp-3326	231	7	change	change	NOUN
fnp-3326	231	8	in	in	ADP
fnp-3326	231	9	αsyn	αsyn	ADJ
fnp-3326	231	10	load	load	NOUN
fnp-3326	231	11	in	in	ADP
fnp-3326	231	12	the	the	DET
fnp-3326	231	13	myenteric	myenteric	ADJ
fnp-3326	231	14	plexus	plexus	NOUN
fnp-3326	231	15	,	,	PUNCT
fnp-3326	231	16	consistent	consistent	ADJ
fnp-3326	231	17	with	with	ADP
fnp-3326	231	18	lack	lack	NOUN
fnp-3326	231	19	of	of	ADP
fnp-3326	231	20	leukocyte	leukocyte	NOUN
fnp-3326	231	21	infiltration	infiltration	NOUN
fnp-3326	231	22	in	in	ADP
fnp-3326	231	23	this	this	DET
fnp-3326	231	24	part	part	NOUN
fnp-3326	231	25	of	of	ADP
fnp-3326	231	26	the	the	DET
fnp-3326	231	27	colonic	colonic	NOUN
fnp-3326	231	28	wall	wall	NOUN
fnp-3326	231	29	(	(	PUNCT
fnp-3326	231	30	fig	fig	NOUN
fnp-3326	231	31	.	.	PUNCT
fnp-3326	232	1	3b	3b	NUM
fnp-3326	232	2	)	)	PUNCT
fnp-3326	232	3	.	.	PUNCT
fnp-3326	233	1	despite	despite	SCONJ
fnp-3326	233	2	the	the	DET
fnp-3326	233	3	high	high	ADJ
fnp-3326	233	4	dose	dose	PROPN
fnp-3326	233	5	,	,	PUNCT
fnp-3326	233	6	lps	lps	PROPN
fnp-3326	233	7	-	-	PUNCT
fnp-3326	233	8	induced	induce	VERB
fnp-3326	233	9	inflammation	inflammation	NOUN
fnp-3326	233	10	did	do	AUX
fnp-3326	233	11	not	not	PART
fnp-3326	233	12	increase	increase	VERB
fnp-3326	233	13	αsyn	αsyn	ADJ
fnp-3326	233	14	accumulation	accumulation	NOUN
fnp-3326	233	15	in	in	ADP
fnp-3326	233	16	the	the	DET
fnp-3326	233	17	colonic	colonic	ADJ
fnp-3326	233	18	nervous	nervous	ADJ
fnp-3326	233	19	plexuses	plexus	NOUN
fnp-3326	233	20	(	(	PUNCT
fnp-3326	233	21	fig	fig	NOUN
fnp-3326	233	22	.	.	PUNCT
fnp-3326	234	1	3c	3c	NUM
fnp-3326	234	2	,	,	PUNCT
fnp-3326	234	3	d	d	NOUN
fnp-3326	234	4	)	)	PUNCT
fnp-3326	234	5	.	.	PUNCT
fnp-3326	235	1	notably	notably	ADV
fnp-3326	235	2	,	,	PUNCT
fnp-3326	235	3	lps	lps	PROPN
fnp-3326	235	4	and	and	CCONJ
fnp-3326	235	5	dss	dss	NOUN
fnp-3326	235	6	resulted	result	VERB
fnp-3326	235	7	in	in	ADP
fnp-3326	235	8	a	a	DET
fnp-3326	235	9	differential	differential	ADJ
fnp-3326	235	10	expression	expression	NOUN
fnp-3326	235	11	of	of	ADP
fnp-3326	235	12	cytokines	cytokine	NOUN
fnp-3326	235	13	,	,	PUNCT
fnp-3326	235	14	and	and	CCONJ
fnp-3326	235	15	consistent	consistent	ADJ
fnp-3326	235	16	with	with	ADP
fnp-3326	235	17	leukocyte	leukocyte	ADJ
fnp-3326	235	18	recruitment	recruitment	NOUN
fnp-3326	235	19	,	,	PUNCT
fnp-3326	235	20	ccl2	ccl2	PROPN
fnp-3326	235	21	was	be	AUX
fnp-3326	235	22	elevated	elevate	VERB
fnp-3326	235	23	in	in	ADP
fnp-3326	235	24	both	both	DET
fnp-3326	235	25	(	(	PUNCT
fnp-3326	235	26	fig	fig	NOUN
fnp-3326	235	27	.	.	PUNCT
fnp-3326	236	1	3f	3f	PROPN
fnp-3326	236	2	,	,	PUNCT
fnp-3326	236	3	g	g	NOUN
fnp-3326	236	4	)	)	PUNCT
fnp-3326	236	5	.	.	PUNCT
fnp-3326	237	1	in	in	ADP
fnp-3326	237	2	the	the	DET
fnp-3326	237	3	lps	lps	PROPN
fnp-3326	237	4	paradigm	paradigm	NOUN
fnp-3326	237	5	,	,	PUNCT
fnp-3326	237	6	mrna	mrna	PROPN
fnp-3326	237	7	for	for	ADP
fnp-3326	237	8	il-10	il-10	PRON
fnp-3326	237	9	was	be	AUX
fnp-3326	237	10	markedly	markedly	ADV
fnp-3326	237	11	elevated	elevate	VERB
fnp-3326	237	12	,	,	PUNCT
fnp-3326	237	13	whereas	whereas	SCONJ
fnp-3326	237	14	dss	dss	NOUN
fnp-3326	237	15	strongly	strongly	ADV
fnp-3326	237	16	increased	increase	VERB
fnp-3326	237	17	il-6	il-6	NOUN
fnp-3326	237	18	and	and	CCONJ
fnp-3326	237	19	also	also	ADV
fnp-3326	237	20	il-1β	il-1β	PROPN
fnp-3326	237	21	but	but	CCONJ
fnp-3326	237	22	not	not	PART
fnp-3326	237	23	il-10	il-10	PRON
fnp-3326	237	24	.	.	PUNCT
fnp-3326	238	1	together	together	ADV
fnp-3326	238	2	these	these	DET
fnp-3326	238	3	results	result	NOUN
fnp-3326	238	4	indicate	indicate	VERB
fnp-3326	238	5	that	that	SCONJ
fnp-3326	238	6	,	,	PUNCT
fnp-3326	238	7	in	in	ADP
fnp-3326	238	8	our	our	PRON
fnp-3326	238	9	model	model	NOUN
fnp-3326	238	10	,	,	PUNCT
fnp-3326	238	11	colonic	colonic	ADJ
fnp-3326	238	12	inflammation	inflammation	NOUN
fnp-3326	238	13	induced	induce	VERB
fnp-3326	238	14	by	by	ADP
fnp-3326	238	15	peroral	peroral	ADJ
fnp-3326	238	16	dss	dss	NOUN
fnp-3326	238	17	but	but	CCONJ
fnp-3326	238	18	not	not	PART
fnp-3326	238	19	intraperitoneal	intraperitoneal	ADJ
fnp-3326	238	20	lps	lps	PROPN
fnp-3326	238	21	increases	increase	VERB
fnp-3326	238	22	the	the	DET
fnp-3326	238	23	accumulation	accumulation	NOUN
fnp-3326	238	24	of	of	ADP
fnp-3326	238	25	αsyn	αsyn	NOUN
fnp-3326	238	26	in	in	ADP
fnp-3326	238	27	the	the	DET
fnp-3326	238	28	colon	colon	NOUN
fnp-3326	238	29	.	.	PUNCT
fnp-3326	239	1	fig	fig	NOUN
fnp-3326	239	2	.	.	PUNCT
fnp-3326	240	1	3	3	NUM
fnp-3326	240	2	colitis	colitis	NOUN
fnp-3326	240	3	induced	induce	VERB
fnp-3326	240	4	by	by	ADP
fnp-3326	240	5	peroral	peroral	ADJ
fnp-3326	240	6	dss	dss	NOUN
fnp-3326	240	7	but	but	CCONJ
fnp-3326	240	8	not	not	PART
fnp-3326	240	9	peritoneal	peritoneal	ADJ
fnp-3326	240	10	lps	lps	PROPN
fnp-3326	240	11	enhances	enhance	VERB
fnp-3326	240	12	αsyn	αsyn	ADJ
fnp-3326	240	13	accumulation	accumulation	NOUN
fnp-3326	240	14	in	in	ADP
fnp-3326	240	15	the	the	DET
fnp-3326	240	16	colonic	colonic	ADJ
fnp-3326	240	17	submucosal	submucosal	NOUN
fnp-3326	240	18	plexus	plexus	NOUN
fnp-3326	240	19	of	of	ADP
fnp-3326	240	20	hemizygous	hemizygous	ADJ
fnp-3326	240	21	(	(	PUNCT
fnp-3326	240	22	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	240	23	transgenic	transgenic	NOUN
fnp-3326	240	24	mice	mouse	NOUN
fnp-3326	240	25	and	and	CCONJ
fnp-3326	240	26	can	can	AUX
fnp-3326	240	27	be	be	AUX
fnp-3326	240	28	increased	increase	VERB
fnp-3326	240	29	by	by	ADP
fnp-3326	240	30	lack	lack	NOUN
fnp-3326	240	31	of	of	ADP
fnp-3326	240	32	monocyte	monocyte	ADJ
fnp-3326	240	33	/	/	SYM
fnp-3326	240	34	macrophage	macrophage	NOUN
fnp-3326	240	35	-	-	PUNCT
fnp-3326	240	36	related	relate	VERB
fnp-3326	240	37	cx3cr1	cx3cr1	NOUN
fnp-3326	240	38	signaling	signal	VERB
fnp-3326	240	39	.	.	PUNCT
fnp-3326	241	1	mice	mouse	NOUN
fnp-3326	241	2	received	receive	VERB
fnp-3326	241	3	in	in	ADP
fnp-3326	241	4	an	an	DET
fnp-3326	241	5	acute	acute	ADJ
fnp-3326	241	6	paradigm	paradigm	NOUN
fnp-3326	241	7	either	either	CCONJ
fnp-3326	241	8	peroral	peroral	ADJ
fnp-3326	241	9	5	5	NUM
fnp-3326	241	10	%	%	NOUN
fnp-3326	241	11	dss	dss	NOUN
fnp-3326	241	12	in	in	ADP
fnp-3326	241	13	their	their	PRON
fnp-3326	241	14	drinking	drinking	NOUN
fnp-3326	241	15	water	water	NOUN
fnp-3326	241	16	or	or	CCONJ
fnp-3326	241	17	intraperitoneally	intraperitoneally	ADV
fnp-3326	241	18	0.5	0.5	NUM
fnp-3326	241	19	mg	mg	PROPN
fnp-3326	241	20	/	/	SYM
fnp-3326	241	21	kg	kg	NOUN
fnp-3326	241	22	lps	lps	PROPN
fnp-3326	241	23	.	.	PUNCT
fnp-3326	242	1	effects	effect	NOUN
fnp-3326	242	2	of	of	ADP
fnp-3326	242	3	dss	dss	NOUN
fnp-3326	242	4	and	and	CCONJ
fnp-3326	242	5	lps	lps	PROPN
fnp-3326	242	6	in	in	ADP
fnp-3326	242	7	the	the	DET
fnp-3326	242	8	colon	colon	NOUN
fnp-3326	242	9	,	,	PUNCT
fnp-3326	242	10	respectively	respectively	ADV
fnp-3326	242	11	,	,	PUNCT
fnp-3326	242	12	were	be	AUX
fnp-3326	242	13	compared	compare	VERB
fnp-3326	242	14	to	to	ADP
fnp-3326	242	15	effects	effect	NOUN
fnp-3326	242	16	induced	induce	VERB
fnp-3326	242	17	by	by	ADP
fnp-3326	242	18	vehicle	vehicle	NOUN
fnp-3326	242	19	(	(	PUNCT
fnp-3326	242	20	see	see	VERB
fnp-3326	242	21	figure	figure	NOUN
fnp-3326	242	22	1c	1c	NOUN
fnp-3326	242	23	for	for	ADP
fnp-3326	242	24	timelines	timeline	NOUN
fnp-3326	242	25	)	)	PUNCT
fnp-3326	242	26	.	.	PUNCT
fnp-3326	243	1	stereological	stereological	ADJ
fnp-3326	243	2	quantification	quantification	NOUN
fnp-3326	243	3	of	of	ADP
fnp-3326	243	4	αsyn	αsyn	ADJ
fnp-3326	243	5	inclusions	inclusion	NOUN
fnp-3326	243	6	in	in	ADP
fnp-3326	243	7	the	the	DET
fnp-3326	243	8	submucosal	submucosal	NOUN
fnp-3326	243	9	plexus	plexus	NOUN
fnp-3326	243	10	as	as	ADP
fnp-3326	243	11	%	%	NOUN
fnp-3326	243	12	area	area	NOUN
fnp-3326	243	13	(	(	PUNCT
fnp-3326	243	14	a	a	PRON
fnp-3326	243	15	,	,	PUNCT
fnp-3326	243	16	c	c	NOUN
fnp-3326	243	17	)	)	PUNCT
fnp-3326	243	18	and	and	CCONJ
fnp-3326	243	19	in	in	ADP
fnp-3326	243	20	the	the	DET
fnp-3326	243	21	mucosal	mucosal	NOUN
fnp-3326	243	22	plexus	plexus	NOUN
fnp-3326	243	23	as	as	ADP
fnp-3326	243	24	particle	particle	NOUN
fnp-3326	243	25	load	load	NOUN
fnp-3326	243	26	per	per	ADP
fnp-3326	243	27	ganglion	ganglion	NOUN
fnp-3326	243	28	(	(	PUNCT
fnp-3326	243	29	b	b	NOUN
fnp-3326	243	30	,	,	PUNCT
fnp-3326	243	31	d	d	NOUN
fnp-3326	243	32	)	)	PUNCT
fnp-3326	243	33	(	(	PUNCT
fnp-3326	243	34	two	two	NUM
fnp-3326	243	35	-	-	PUNCT
fnp-3326	243	36	way	way	NOUN
fnp-3326	243	37	anova	anova	X
fnp-3326	243	38	with	with	ADP
fnp-3326	243	39	tukey	tukey	PROPN
fnp-3326	243	40	post	post	X
fnp-3326	243	41	hoc	hoc	X
fnp-3326	243	42	test	test	NOUN
fnp-3326	243	43	;	;	PUNCT
fnp-3326	243	44	covariates	covariate	VERB
fnp-3326	243	45	genotype	genotype	NOUN
fnp-3326	243	46	and	and	CCONJ
fnp-3326	243	47	treatment	treatment	NOUN
fnp-3326	243	48	paradigm	paradigm	NOUN
fnp-3326	243	49	)	)	PUNCT
fnp-3326	243	50	.	.	PUNCT
fnp-3326	244	1	e	e	PROPN
fnp-3326	244	2	representative	representative	ADJ
fnp-3326	244	3	2d	2d	NUM
fnp-3326	244	4	stacks	stack	NOUN
fnp-3326	244	5	of	of	ADP
fnp-3326	244	6	confocal	confocal	ADJ
fnp-3326	244	7	images	image	NOUN
fnp-3326	244	8	of	of	ADP
fnp-3326	244	9	intracellular	intracellular	ADJ
fnp-3326	244	10	αsyn	αsyn	ADJ
fnp-3326	244	11	inclusions	inclusion	NOUN
fnp-3326	244	12	(	(	PUNCT
fnp-3326	244	13	red	red	ADJ
fnp-3326	244	14	,	,	PUNCT
fnp-3326	244	15	human	human	ADJ
fnp-3326	244	16	αsyn	αsyn	NOUN
fnp-3326	244	17	specific	specific	ADJ
fnp-3326	244	18	monoclonal	monoclonal	NOUN
fnp-3326	244	19	antibody	antibody	NOUN
fnp-3326	244	20	clone	clone	NOUN
fnp-3326	244	21	211	211	NUM
fnp-3326	244	22	;	;	PUNCT
fnp-3326	244	23	arrow	arrow	NOUN
fnp-3326	244	24	heads	head	NOUN
fnp-3326	244	25	pointing	point	VERB
fnp-3326	244	26	to	to	ADP
fnp-3326	244	27	some	some	DET
fnp-3326	244	28	selected	select	VERB
fnp-3326	244	29	inclusions	inclusion	NOUN
fnp-3326	244	30	)	)	PUNCT
fnp-3326	244	31	in	in	ADP
fnp-3326	244	32	a	a	DET
fnp-3326	244	33	ganglion	ganglion	NOUN
fnp-3326	244	34	of	of	ADP
fnp-3326	244	35	the	the	DET
fnp-3326	244	36	myenteric	myenteric	ADJ
fnp-3326	244	37	plexus	plexus	NOUN
fnp-3326	244	38	(	(	PUNCT
fnp-3326	244	39	green	green	ADJ
fnp-3326	244	40	,	,	PUNCT
fnp-3326	244	41	peripherin	peripherin	NOUN
fnp-3326	244	42	)	)	PUNCT
fnp-3326	244	43	with	with	ADP
fnp-3326	244	44	cellular	cellular	ADJ
fnp-3326	244	45	nuclei	nucleus	NOUN
fnp-3326	244	46	in	in	ADP
fnp-3326	244	47	blue	blue	ADJ
fnp-3326	244	48	(	(	PUNCT
fnp-3326	244	49	dapi	dapi	ADJ
fnp-3326	244	50	)	)	PUNCT
fnp-3326	244	51	.	.	PUNCT
fnp-3326	245	1	scale	scale	NOUN
fnp-3326	245	2	bar	bar	NOUN
fnp-3326	245	3	:	:	PUNCT
fnp-3326	245	4	50	50	NUM
fnp-3326	245	5	μm	μm	NOUN
fnp-3326	245	6	.	.	PUNCT
fnp-3326	246	1	gene	gene	NOUN
fnp-3326	246	2	expression	expression	NOUN
fnp-3326	246	3	analysis	analysis	NOUN
fnp-3326	246	4	of	of	ADP
fnp-3326	246	5	selected	select	VERB
fnp-3326	246	6	cytokines	cytokine	NOUN
fnp-3326	246	7	in	in	ADP
fnp-3326	246	8	the	the	DET
fnp-3326	246	9	colon	colon	NOUN
fnp-3326	246	10	of	of	ADP
fnp-3326	246	11	(	(	PUNCT
fnp-3326	246	12	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	246	13	transgenic	transgenic	NOUN
fnp-3326	246	14	mice	mouse	NOUN
fnp-3326	246	15	that	that	PRON
fnp-3326	246	16	received	receive	VERB
fnp-3326	246	17	either	either	CCONJ
fnp-3326	246	18	acute	acute	ADJ
fnp-3326	246	19	dss	dss	NOUN
fnp-3326	246	20	(	(	PUNCT
fnp-3326	246	21	f	f	NOUN
fnp-3326	246	22	)	)	PUNCT
fnp-3326	246	23	or	or	CCONJ
fnp-3326	246	24	lps	lps	PROPN
fnp-3326	246	25	(	(	PUNCT
fnp-3326	246	26	g	g	NOUN
fnp-3326	246	27	)	)	PUNCT
fnp-3326	246	28	compared	compare	VERB
fnp-3326	246	29	to	to	ADP
fnp-3326	246	30	their	their	PRON
fnp-3326	246	31	respective	respective	ADJ
fnp-3326	246	32	vehicle	vehicle	NOUN
fnp-3326	246	33	or	or	CCONJ
fnp-3326	246	34	water	water	NOUN
fnp-3326	246	35	controls	control	NOUN
fnp-3326	246	36	.	.	PUNCT
fnp-3326	247	1	note	note	VERB
fnp-3326	247	2	the	the	DET
fnp-3326	247	3	strong	strong	ADJ
fnp-3326	247	4	increase	increase	NOUN
fnp-3326	247	5	in	in	ADP
fnp-3326	247	6	il-6	il-6	NOUN
fnp-3326	247	7	and	and	CCONJ
fnp-3326	247	8	the	the	DET
fnp-3326	247	9	lack	lack	NOUN
fnp-3326	247	10	of	of	ADP
fnp-3326	247	11	elevation	elevation	NOUN
fnp-3326	247	12	of	of	ADP
fnp-3326	247	13	il-10	il-10	NOUN
fnp-3326	247	14	in	in	ADP
fnp-3326	247	15	the	the	DET
fnp-3326	247	16	dss	dss	NOUN
fnp-3326	247	17	paradigm	paradigm	NOUN
fnp-3326	247	18	compared	compare	VERB
fnp-3326	247	19	to	to	ADP
fnp-3326	247	20	the	the	DET
fnp-3326	247	21	lps	lps	PROPN
fnp-3326	247	22	paradigm	paradigm	NOUN
fnp-3326	247	23	indicating	indicate	VERB
fnp-3326	247	24	a	a	DET
fnp-3326	247	25	different	different	ADJ
fnp-3326	247	26	inflammatory	inflammatory	ADJ
fnp-3326	247	27	colonic	colonic	NOUN
fnp-3326	247	28	milieu	milieu	NOUN
fnp-3326	247	29	despite	despite	SCONJ
fnp-3326	247	30	the	the	DET
fnp-3326	247	31	abundant	abundant	ADJ
fnp-3326	247	32	leukocyte	leukocyte	NOUN
fnp-3326	247	33	infiltration	infiltration	NOUN
fnp-3326	247	34	in	in	ADP
fnp-3326	247	35	both	both	DET
fnp-3326	247	36	paradigms	paradigm	NOUN
fnp-3326	247	37	.	.	PUNCT
fnp-3326	248	1	n	n	PRON
fnp-3326	248	2	=	=	SYM
fnp-3326	248	3	5	5	NUM
fnp-3326	248	4	-	-	SYM
fnp-3326	248	5	8	8	NUM
fnp-3326	248	6	per	per	ADP
fnp-3326	248	7	group	group	NOUN
fnp-3326	248	8	;	;	PUNCT
fnp-3326	248	9	mean	mean	VERB
fnp-3326	248	10	and	and	CCONJ
fnp-3326	248	11	s.e.m	s.e.m	NOUN
fnp-3326	248	12	.	.	PROPN
fnp-3326	248	13	;	;	PUNCT
fnp-3326	248	14	student	student	NOUN
fnp-3326	248	15	’s	’s	PART
fnp-3326	248	16	t	t	PROPN
fnp-3326	248	17	-	-	PUNCT
fnp-3326	248	18	test	test	NOUN
fnp-3326	248	19	between	between	ADP
fnp-3326	248	20	inflammatory	inflammatory	ADJ
fnp-3326	248	21	agent	agent	NOUN
fnp-3326	248	22	and	and	CCONJ
fnp-3326	248	23	vehicle	vehicle	NOUN
fnp-3326	248	24	for	for	ADP
fnp-3326	248	25	individual	individual	ADJ
fnp-3326	248	26	cytokines	cytokine	NOUN
fnp-3326	248	27	.	.	PUNCT
fnp-3326	249	1	lack	lack	NOUN
fnp-3326	249	2	of	of	ADP
fnp-3326	249	3	monocyte	monocyte	NOUN
fnp-3326	249	4	/	/	SYM
fnp-3326	249	5	macrophage	macrophage	NOUN
fnp-3326	249	6	related	related	ADJ
fnp-3326	249	7	cx3cr1	cx3cr1	NOUN
fnp-3326	249	8	signaling	signal	VERB
fnp-3326	249	9	during	during	ADP
fnp-3326	249	10	dss	dss	NOUN
fnp-3326	249	11	colitis	colitis	NOUN
fnp-3326	249	12	increases	increase	VERB
fnp-3326	249	13	αsyn	αsyn	ADJ
fnp-3326	249	14	load	load	NOUN
fnp-3326	249	15	in	in	ADP
fnp-3326	249	16	the	the	DET
fnp-3326	249	17	submucosal	submucosal	NOUN
fnp-3326	249	18	plexus	plexus	NOUN
fnp-3326	249	19	of	of	ADP
fnp-3326	249	20	αsyn	αsyn	ADJ
fnp-3326	249	21	transgenic	transgenic	NOUN
fnp-3326	249	22	mice	mouse	NOUN
fnp-3326	249	23	given	give	VERB
fnp-3326	249	24	the	the	DET
fnp-3326	249	25	role	role	NOUN
fnp-3326	249	26	of	of	ADP
fnp-3326	249	27	monocytes	monocyte	NOUN
fnp-3326	249	28	/	/	SYM
fnp-3326	249	29	macrophages	macrophage	NOUN
fnp-3326	249	30	in	in	ADP
fnp-3326	249	31	ibd	ibd	NOUN
fnp-3326	249	32	and	and	CCONJ
fnp-3326	249	33	in	in	ADP
fnp-3326	249	34	the	the	DET
fnp-3326	249	35	related	related	ADJ
fnp-3326	249	36	dss	dss	NOUN
fnp-3326	249	37	paradigm	paradigm	NOUN
fnp-3326	249	38	,	,	PUNCT
fnp-3326	249	39	we	we	PRON
fnp-3326	249	40	hypothesized	hypothesize	VERB
fnp-3326	249	41	further	far	ADV
fnp-3326	249	42	that	that	SCONJ
fnp-3326	249	43	modulating	modulate	VERB
fnp-3326	249	44	monocytes	monocyte	NOUN
fnp-3326	249	45	/	/	SYM
fnp-3326	249	46	macrophages	macrophage	NOUN
fnp-3326	249	47	may	may	AUX
fnp-3326	249	48	affect	affect	VERB
fnp-3326	249	49	accumulation	accumulation	NOUN
fnp-3326	249	50	of	of	ADP
fnp-3326	249	51	αsyn	αsyn	NOUN
fnp-3326	249	52	in	in	ADP
fnp-3326	249	53	our	our	PRON
fnp-3326	249	54	dss	dss	NOUN
fnp-3326	249	55	model	model	NOUN
fnp-3326	249	56	as	as	ADV
fnp-3326	249	57	well	well	ADV
fnp-3326	249	58	.	.	PUNCT
fnp-3326	250	1	in	in	ADP
fnp-3326	250	2	a	a	DET
fnp-3326	250	3	first	first	ADJ
fnp-3326	250	4	set	set	NOUN
fnp-3326	250	5	of	of	ADP
fnp-3326	250	6	experiments	experiment	NOUN
fnp-3326	250	7	we	we	PRON
fnp-3326	250	8	manipulated	manipulate	VERB
fnp-3326	250	9	monocytes	monocyte	NOUN
fnp-3326	250	10	/	/	SYM
fnp-3326	250	11	macrophages	macrophage	NOUN
fnp-3326	250	12	genetically	genetically	ADV
fnp-3326	250	13	by	by	ADP
fnp-3326	250	14	crossing	cross	VERB
fnp-3326	250	15	(	(	PUNCT
fnp-3326	250	16	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	250	17	transgenic	transgenic	NOUN
fnp-3326	250	18	mice	mouse	NOUN
fnp-3326	250	19	with	with	ADP
fnp-3326	250	20	mice	mouse	NOUN
fnp-3326	250	21	that	that	PRON
fnp-3326	250	22	have	have	VERB
fnp-3326	250	23	a	a	DET
fnp-3326	250	24	deletion	deletion	NOUN
fnp-3326	250	25	for	for	ADP
fnp-3326	250	26	the	the	DET
fnp-3326	250	27	fractalkine	fractalkine	NOUN
fnp-3326	250	28	receptor	receptor	NOUN
fnp-3326	250	29	cx3cr1	cx3cr1	NOUN
fnp-3326	250	30	(	(	PUNCT
fnp-3326	250	31	cx3cr1	cx3cr1	NOUN
fnp-3326	250	32	-	-	PUNCT
fnp-3326	250	33	gfp	gfp	NOUN
fnp-3326	250	34	knock	knock	NOUN
fnp-3326	250	35	-	-	PUNCT
fnp-3326	250	36	in	in	ADP
fnp-3326	250	37	mice	mouse	NOUN
fnp-3326	250	38	)	)	PUNCT
fnp-3326	250	39	(	(	PUNCT
fnp-3326	250	40	fig	fig	NOUN
fnp-3326	250	41	.	.	PUNCT
fnp-3326	250	42	3a	3a	NUM
fnp-3326	250	43	,	,	PUNCT
fnp-3326	250	44	b	b	NOUN
fnp-3326	250	45	)	)	PUNCT
fnp-3326	250	46	.	.	PUNCT
fnp-3326	251	1	the	the	DET
fnp-3326	251	2	cx3cr1	cx3cr1	NOUN
fnp-3326	251	3	-	-	PUNCT
fnp-3326	251	4	cx3cl1	cx3cl1	ADJ
fnp-3326	251	5	axis	axis	NOUN
fnp-3326	251	6	plays	play	VERB
fnp-3326	251	7	an	an	DET
fnp-3326	251	8	important	important	ADJ
fnp-3326	251	9	role	role	NOUN
fnp-3326	251	10	in	in	ADP
fnp-3326	251	11	maintaining	maintain	VERB
fnp-3326	251	12	the	the	DET
fnp-3326	251	13	function	function	NOUN
fnp-3326	251	14	of	of	ADP
fnp-3326	251	15	the	the	DET
fnp-3326	251	16	lamina	lamina	ADJ
fnp-3326	251	17	propria	propria	PROPN
fnp-3326	251	18	macrophage	macrophage	ADJ
fnp-3326	251	19	population	population	NOUN
fnp-3326	251	20	of	of	ADP
fnp-3326	251	21	the	the	DET
fnp-3326	251	22	gastrointestinal	gastrointestinal	ADJ
fnp-3326	251	23	wall	wall	NOUN
fnp-3326	251	24	and	and	CCONJ
fnp-3326	251	25	lack	lack	NOUN
fnp-3326	251	26	of	of	ADP
fnp-3326	251	27	this	this	DET
fnp-3326	251	28	signaling	signal	VERB
fnp-3326	251	29	pathway	pathway	NOUN
fnp-3326	251	30	in	in	ADP
fnp-3326	251	31	experimental	experimental	ADJ
fnp-3326	251	32	colitis	colitis	NOUN
fnp-3326	251	33	models	model	NOUN
fnp-3326	251	34	may	may	AUX
fnp-3326	251	35	either	either	CCONJ
fnp-3326	251	36	aggravate	aggravate	VERB
fnp-3326	251	37	or	or	CCONJ
fnp-3326	251	38	ameliorate	ameliorate	VERB
fnp-3326	251	39	the	the	DET
fnp-3326	251	40	induced	induced	ADJ
fnp-3326	251	41	pathology	pathology	NOUN
fnp-3326	251	42	[	[	X
fnp-3326	251	43	50–52	50–52	NUM
fnp-3326	251	44	]	]	PUNCT
fnp-3326	251	45	.	.	PUNCT
fnp-3326	252	1	in	in	ADP
fnp-3326	252	2	our	our	PRON
fnp-3326	252	3	experiment	experiment	NOUN
fnp-3326	252	4	,	,	PUNCT
fnp-3326	252	5	the	the	DET
fnp-3326	252	6	area	area	NOUN
fnp-3326	252	7	covered	cover	VERB
fnp-3326	252	8	by	by	ADP
fnp-3326	252	9	infiltrating	infiltrate	VERB
fnp-3326	252	10	leukocytes	leukocyte	NOUN
fnp-3326	252	11	following	follow	VERB
fnp-3326	252	12	exposure	exposure	NOUN
fnp-3326	252	13	to	to	ADP
fnp-3326	252	14	dss	dss	NOUN
fnp-3326	252	15	was	be	AUX
fnp-3326	252	16	near	near	ADP
fnp-3326	252	17	the	the	DET
fnp-3326	252	18	mucosa	mucosa	NOUN
fnp-3326	252	19	and	and	CCONJ
fnp-3326	252	20	submucosa	submucosa	PROPN
fnp-3326	252	21	and	and	CCONJ
fnp-3326	252	22	was	be	AUX
fnp-3326	252	23	not	not	PART
fnp-3326	252	24	significantly	significantly	ADV
fnp-3326	252	25	higher	high	ADJ
fnp-3326	252	26	in	in	ADP
fnp-3326	252	27	the	the	DET
fnp-3326	252	28	cx3cr1	cx3cr1	ADJ
fnp-3326	252	29	-	-	ADJ
fnp-3326	252	30	deficient	deficient	ADJ
fnp-3326	252	31	αsyn	αsyn	ADJ
fnp-3326	252	32	transgenic	transgenic	NOUN
fnp-3326	252	33	mice	mouse	NOUN
fnp-3326	252	34	than	than	ADP
fnp-3326	252	35	in	in	ADP
fnp-3326	252	36	the	the	DET
fnp-3326	252	37	cx3cr1	cx3cr1	NOUN
fnp-3326	252	38	-	-	ADJ
fnp-3326	252	39	competent	competent	ADJ
fnp-3326	252	40	mice	mouse	NOUN
fnp-3326	252	41	(	(	PUNCT
fnp-3326	252	42	suppl	suppl	PROPN
fnp-3326	252	43	.	.	PUNCT
fnp-3326	252	44	fig	fig	PROPN
fnp-3326	252	45	.	.	PUNCT
fnp-3326	253	1	3a	3a	NUM
fnp-3326	253	2	)	)	PUNCT
fnp-3326	253	3	.	.	PUNCT
fnp-3326	254	1	however	however	ADV
fnp-3326	254	2	,	,	PUNCT
fnp-3326	254	3	a	a	DET
fnp-3326	254	4	significantly	significantly	ADV
fnp-3326	254	5	higher	high	ADJ
fnp-3326	254	6	level	level	NOUN
fnp-3326	254	7	of	of	ADP
fnp-3326	254	8	αsyn	αsyn	NOUN
fnp-3326	254	9	accumulated	accumulate	VERB
fnp-3326	254	10	in	in	ADP
fnp-3326	254	11	the	the	DET
fnp-3326	254	12	submucosal	submucosal	NOUN
fnp-3326	254	13	plexus	plexus	NOUN
fnp-3326	254	14	in	in	ADP
fnp-3326	254	15	αsyn	αsyn	ADJ
fnp-3326	254	16	transgenic	transgenic	NOUN
fnp-3326	254	17	mice	mouse	NOUN
fnp-3326	254	18	lacking	lack	VERB
fnp-3326	254	19	cx3cr1	cx3cr1	NOUN
fnp-3326	254	20	compared	compare	VERB
fnp-3326	254	21	to	to	ADP
fnp-3326	254	22	αsyn	αsyn	ADJ
fnp-3326	254	23	transgenic	transgenic	NOUN
fnp-3326	254	24	mice	mouse	NOUN
fnp-3326	254	25	expressing	express	VERB
fnp-3326	254	26	cx3cr1	cx3cr1	NOUN
fnp-3326	254	27	(	(	PUNCT
fnp-3326	254	28	p	p	NOUN
fnp-3326	254	29	=	=	NOUN
fnp-3326	254	30	0.001	0.001	NUM
fnp-3326	254	31	,	,	PUNCT
fnp-3326	254	32	two	two	NUM
fnp-3326	254	33	-	-	PUNCT
fnp-3326	254	34	way	way	NOUN
fnp-3326	254	35	anova	anova	X
fnp-3326	254	36	with	with	ADP
fnp-3326	254	37	tukey	tukey	PROPN
fnp-3326	254	38	hsd	hsd	PROPN
fnp-3326	254	39	post	post	ADJ
fnp-3326	254	40	-	-	ADJ
fnp-3326	254	41	hoc	hoc	ADJ
fnp-3326	254	42	analysis	analysis	NOUN
fnp-3326	254	43	;	;	PUNCT
fnp-3326	254	44	fig	fig	NOUN
fnp-3326	254	45	.	.	PUNCT
fnp-3326	255	1	3a	3a	NUM
fnp-3326	255	2	)	)	PUNCT
fnp-3326	255	3	.	.	PUNCT
fnp-3326	256	1	in	in	ADP
fnp-3326	256	2	the	the	DET
fnp-3326	256	3	myenteric	myenteric	ADJ
fnp-3326	256	4	plexus	plexus	NOUN
fnp-3326	256	5	,	,	PUNCT
fnp-3326	256	6	we	we	PRON
fnp-3326	256	7	found	find	VERB
fnp-3326	256	8	no	no	DET
fnp-3326	256	9	marked	marked	ADJ
fnp-3326	256	10	increase	increase	NOUN
fnp-3326	256	11	in	in	ADP
fnp-3326	256	12	αsyn	αsyn	ADJ
fnp-3326	256	13	accumulation	accumulation	NOUN
fnp-3326	256	14	in	in	ADP
fnp-3326	256	15	neither	neither	CCONJ
fnp-3326	256	16	the	the	DET
fnp-3326	256	17	αsyn	αsyn	ADJ
fnp-3326	256	18	transgenic	transgenic	NOUN
fnp-3326	256	19	mice	mouse	NOUN
fnp-3326	256	20	with	with	ADP
fnp-3326	256	21	normal	normal	ADJ
fnp-3326	256	22	cx3cr1	cx3cr1	NOUN
fnp-3326	256	23	nor	nor	CCONJ
fnp-3326	256	24	the	the	DET
fnp-3326	256	25	αsyn	αsyn	ADJ
fnp-3326	256	26	transgenic	transgenic	NOUN
fnp-3326	256	27	mice	mouse	NOUN
fnp-3326	256	28	deficient	deficient	ADJ
fnp-3326	256	29	in	in	ADP
fnp-3326	256	30	cx3cr1	cx3cr1	NOUN
fnp-3326	256	31	,	,	PUNCT
fnp-3326	256	32	indicating	indicate	VERB
fnp-3326	256	33	as	as	ADP
fnp-3326	256	34	in	in	ADP
fnp-3326	256	35	the	the	DET
fnp-3326	256	36	experiments	experiment	NOUN
fnp-3326	256	37	above	above	ADP
fnp-3326	256	38	a	a	DET
fnp-3326	256	39	possible	possible	ADJ
fnp-3326	256	40	prominent	prominent	ADJ
fnp-3326	256	41	role	role	NOUN
fnp-3326	256	42	for	for	ADP
fnp-3326	256	43	the	the	DET
fnp-3326	256	44	localization	localization	NOUN
fnp-3326	256	45	of	of	ADP
fnp-3326	256	46	leukocyte	leukocyte	NOUN
fnp-3326	256	47	infiltration	infiltration	NOUN
fnp-3326	256	48	in	in	ADP
fnp-3326	256	49	the	the	DET
fnp-3326	256	50	process	process	NOUN
fnp-3326	256	51	of	of	ADP
fnp-3326	256	52	αsyn	αsyn	ADJ
fnp-3326	256	53	accumulation	accumulation	NOUN
fnp-3326	256	54	in	in	ADP
fnp-3326	256	55	the	the	DET
fnp-3326	256	56	submucosa	submucosa	PROPN
fnp-3326	256	57	(	(	PUNCT
fnp-3326	256	58	fig	fig	NOUN
fnp-3326	256	59	.	.	PUNCT
fnp-3326	257	1	3b	3b	NUM
fnp-3326	257	2	)	)	PUNCT
fnp-3326	257	3	.	.	PUNCT
fnp-3326	258	1	collectively	collectively	ADV
fnp-3326	258	2	,	,	PUNCT
fnp-3326	258	3	our	our	PRON
fnp-3326	258	4	results	result	NOUN
fnp-3326	258	5	in	in	ADP
fnp-3326	258	6	cx3cr1	cx3cr1	ADJ
fnp-3326	258	7	-	-	ADJ
fnp-3326	258	8	deficient	deficient	ADJ
fnp-3326	258	9	αsyn	αsyn	ADJ
fnp-3326	258	10	transgenic	transgenic	NOUN
fnp-3326	258	11	mice	mouse	NOUN
fnp-3326	258	12	provide	provide	VERB
fnp-3326	258	13	a	a	DET
fnp-3326	258	14	potential	potential	ADJ
fnp-3326	258	15	association	association	NOUN
fnp-3326	258	16	between	between	ADP
fnp-3326	258	17	monocyte	monocyte	NOUN
fnp-3326	258	18	/	/	SYM
fnp-3326	258	19	macrophage	macrophage	ADJ
fnp-3326	258	20	signaling	signaling	NOUN
fnp-3326	258	21	and	and	CCONJ
fnp-3326	258	22	αsyn	αsyn	NOUN
fnp-3326	258	23	accumulation	accumulation	NOUN
fnp-3326	258	24	in	in	ADP
fnp-3326	258	25	ens	ens	PROPN
fnp-3326	258	26	in	in	ADP
fnp-3326	258	27	this	this	DET
fnp-3326	258	28	experimental	experimental	ADJ
fnp-3326	258	29	ibd	ibd	PROPN
fnp-3326	258	30	model	model	NOUN
fnp-3326	258	31	.	.	PUNCT
fnp-3326	259	1	systemic	systemic	ADJ
fnp-3326	259	2	il-10	il-10	PRON
fnp-3326	259	3	reduces	reduce	VERB
fnp-3326	259	4	dss	dss	NOUN
fnp-3326	259	5	-	-	PUNCT
fnp-3326	259	6	induced	induce	VERB
fnp-3326	259	7	colitis	colitis	NOUN
fnp-3326	259	8	and	and	CCONJ
fnp-3326	259	9	associated	associated	ADJ
fnp-3326	259	10	enteric	enteric	ADJ
fnp-3326	259	11	αsyn	αsyn	ADJ
fnp-3326	259	12	accumulation	accumulation	NOUN
fnp-3326	259	13	in	in	ADP
fnp-3326	259	14	αsyn	αsyn	ADJ
fnp-3326	259	15	transgenic	transgenic	NOUN
fnp-3326	259	16	mice	mouse	NOUN
fnp-3326	259	17	to	to	PART
fnp-3326	259	18	continue	continue	VERB
fnp-3326	259	19	testing	test	VERB
fnp-3326	259	20	the	the	DET
fnp-3326	259	21	hypothesis	hypothesis	NOUN
fnp-3326	259	22	that	that	SCONJ
fnp-3326	259	23	modulating	modulate	VERB
fnp-3326	259	24	monocytes	monocyte	NOUN
fnp-3326	259	25	/	/	SYM
fnp-3326	259	26	macrophages	macrophage	NOUN
fnp-3326	259	27	may	may	AUX
fnp-3326	259	28	affect	affect	VERB
fnp-3326	259	29	accumulation	accumulation	NOUN
fnp-3326	259	30	of	of	ADP
fnp-3326	259	31	αsyn	αsyn	NOUN
fnp-3326	259	32	in	in	ADP
fnp-3326	259	33	our	our	PRON
fnp-3326	259	34	dss	dss	NOUN
fnp-3326	259	35	model	model	NOUN
fnp-3326	259	36	we	we	PRON
fnp-3326	259	37	moved	move	VERB
fnp-3326	259	38	to	to	ADP
fnp-3326	259	39	a	a	DET
fnp-3326	259	40	pharmacological	pharmacological	ADJ
fnp-3326	259	41	modulation	modulation	NOUN
fnp-3326	259	42	of	of	ADP
fnp-3326	259	43	this	this	DET
fnp-3326	259	44	cellular	cellular	ADJ
fnp-3326	259	45	subset	subset	NOUN
fnp-3326	259	46	.	.	PUNCT
fnp-3326	260	1	interleukin-10	interleukin-10	PROPN
fnp-3326	260	2	(	(	PUNCT
fnp-3326	260	3	il-10	il-10	PRON
fnp-3326	260	4	)	)	PUNCT
fnp-3326	260	5	is	be	AUX
fnp-3326	260	6	an	an	DET
fnp-3326	260	7	important	important	ADJ
fnp-3326	260	8	regulator	regulator	NOUN
fnp-3326	260	9	of	of	ADP
fnp-3326	260	10	monocytes	monocyte	NOUN
fnp-3326	260	11	/	/	SYM
fnp-3326	260	12	macrophages	macrophage	NOUN
fnp-3326	260	13	,	,	PUNCT
fnp-3326	260	14	and	and	CCONJ
fnp-3326	260	15	genetic	genetic	ADJ
fnp-3326	260	16	ablation	ablation	NOUN
fnp-3326	260	17	of	of	ADP
fnp-3326	260	18	il-10	il-10	PRON
fnp-3326	260	19	signaling	signal	VERB
fnp-3326	260	20	or	or	CCONJ
fnp-3326	260	21	blocking	block	VERB
fnp-3326	260	22	il-10	il-10	NOUN
fnp-3326	260	23	with	with	ADP
fnp-3326	260	24	specific	specific	ADJ
fnp-3326	260	25	antibodies	antibody	NOUN
fnp-3326	260	26	has	have	AUX
fnp-3326	260	27	been	be	AUX
fnp-3326	260	28	reported	report	VERB
fnp-3326	260	29	to	to	PART
fnp-3326	260	30	enhance	enhance	VERB
fnp-3326	260	31	dss	dss	NOUN
fnp-3326	260	32	colitis	colitis	NOUN
fnp-3326	260	33	[	[	X
fnp-3326	260	34	53,54	53,54	NUM
fnp-3326	260	35	]	]	X
fnp-3326	260	36	.	.	PUNCT
fnp-3326	261	1	in	in	ADP
fnp-3326	261	2	the	the	DET
fnp-3326	261	3	experiments	experiment	NOUN
fnp-3326	261	4	with	with	ADP
fnp-3326	261	5	lps	lps	PROPN
fnp-3326	261	6	we	we	PRON
fnp-3326	261	7	had	have	AUX
fnp-3326	261	8	also	also	ADV
fnp-3326	261	9	noted	note	VERB
fnp-3326	261	10	an	an	DET
fnp-3326	261	11	increase	increase	NOUN
fnp-3326	261	12	of	of	ADP
fnp-3326	261	13	il-10	il-10	NOUN
fnp-3326	261	14	compared	compare	VERB
fnp-3326	261	15	with	with	ADP
fnp-3326	261	16	the	the	DET
fnp-3326	261	17	dss	dss	NOUN
fnp-3326	261	18	paradigm	paradigm	NOUN
fnp-3326	261	19	and	and	CCONJ
fnp-3326	261	20	lps	lps	PROPN
fnp-3326	261	21	inflammation	inflammation	NOUN
fnp-3326	261	22	was	be	AUX
fnp-3326	261	23	in	in	ADP
fnp-3326	261	24	contrast	contrast	NOUN
fnp-3326	261	25	to	to	ADP
fnp-3326	261	26	dss	dss	NOUN
fnp-3326	261	27	colitis	colitis	NOUN
fnp-3326	261	28	not	not	PART
fnp-3326	261	29	associated	associate	VERB
fnp-3326	261	30	with	with	ADP
fnp-3326	261	31	increased	increase	VERB
fnp-3326	261	32	αsyn	αsyn	ADJ
fnp-3326	261	33	accumulation	accumulation	NOUN
fnp-3326	261	34	in	in	ADP
fnp-3326	261	35	the	the	DET
fnp-3326	261	36	ens	ens	PROPN
fnp-3326	261	37	(	(	PUNCT
fnp-3326	261	38	fig	fig	NOUN
fnp-3326	261	39	.	.	PUNCT
fnp-3326	262	1	3	3	NUM
fnp-3326	262	2	)	)	PUNCT
fnp-3326	262	3	.	.	PUNCT
fnp-3326	263	1	to	to	PART
fnp-3326	263	2	mimic	mimic	VERB
fnp-3326	263	3	the	the	DET
fnp-3326	263	4	effect	effect	NOUN
fnp-3326	263	5	of	of	ADP
fnp-3326	263	6	higher	high	ADJ
fnp-3326	263	7	levels	level	NOUN
fnp-3326	263	8	of	of	ADP
fnp-3326	263	9	il-10	il-10	NOUN
fnp-3326	263	10	in	in	ADP
fnp-3326	263	11	an	an	DET
fnp-3326	263	12	acute	acute	ADJ
fnp-3326	263	13	model	model	NOUN
fnp-3326	263	14	of	of	ADP
fnp-3326	263	15	dss	dss	NOUN
fnp-3326	263	16	colitis	colitis	NOUN
fnp-3326	263	17	(	(	PUNCT
fnp-3326	263	18	5	5	NUM
fnp-3326	263	19	%	%	NOUN
fnp-3326	263	20	dss	dss	NOUN
fnp-3326	263	21	for	for	ADP
fnp-3326	263	22	5	5	NUM
fnp-3326	263	23	days	day	NOUN
fnp-3326	263	24	+	+	CCONJ
fnp-3326	263	25	2	2	NUM
fnp-3326	263	26	days	day	NOUN
fnp-3326	263	27	normal	normal	ADJ
fnp-3326	263	28	drinking	drinking	NOUN
fnp-3326	263	29	water	water	NOUN
fnp-3326	263	30	,	,	PUNCT
fnp-3326	263	31	fig	fig	NOUN
fnp-3326	263	32	.	.	PUNCT
fnp-3326	264	1	1c	1c	NOUN
fnp-3326	264	2	)	)	PUNCT
fnp-3326	264	3	,	,	PUNCT
fnp-3326	264	4	we	we	PRON
fnp-3326	264	5	administered	administer	VERB
fnp-3326	264	6	intraperitoneally	intraperitoneally	ADV
fnp-3326	264	7	recombinant	recombinant	ADJ
fnp-3326	264	8	murine	murine	ADJ
fnp-3326	264	9	il-10	il-10	X
fnp-3326	264	10	(	(	PUNCT
fnp-3326	264	11	mil10	mil10	PROPN
fnp-3326	264	12	)	)	PUNCT
fnp-3326	264	13	in	in	ADP
fnp-3326	264	14	this	this	DET
fnp-3326	264	15	paradigm	paradigm	NOUN
fnp-3326	264	16	.	.	PUNCT
fnp-3326	265	1	the	the	DET
fnp-3326	265	2	half	half	ADJ
fnp-3326	265	3	-	-	PUNCT
fnp-3326	265	4	life	life	NOUN
fnp-3326	265	5	of	of	ADP
fnp-3326	265	6	injected	inject	VERB
fnp-3326	265	7	recombinant	recombinant	ADJ
fnp-3326	265	8	il-10	il-10	PRON
fnp-3326	265	9	protein	protein	NOUN
fnp-3326	265	10	in	in	ADP
fnp-3326	265	11	blood	blood	NOUN
fnp-3326	265	12	is	be	AUX
fnp-3326	265	13	very	very	ADV
fnp-3326	265	14	short	short	ADJ
fnp-3326	265	15	.	.	PUNCT
fnp-3326	266	1	to	to	PART
fnp-3326	266	2	reduce	reduce	VERB
fnp-3326	266	3	the	the	DET
fnp-3326	266	4	number	number	NOUN
fnp-3326	266	5	of	of	ADP
fnp-3326	266	6	injections	injection	NOUN
fnp-3326	266	7	,	,	PUNCT
fnp-3326	266	8	we	we	PRON
fnp-3326	266	9	extended	extend	VERB
fnp-3326	266	10	the	the	DET
fnp-3326	266	11	half	half	ADJ
fnp-3326	266	12	-	-	PUNCT
fnp-3326	266	13	life	life	NOUN
fnp-3326	266	14	of	of	ADP
fnp-3326	266	15	mil-10	mil-10	NOUN
fnp-3326	266	16	in	in	ADP
fnp-3326	266	17	circulation	circulation	NOUN
fnp-3326	266	18	by	by	ADP
fnp-3326	266	19	engineering	engineer	VERB
fnp-3326	266	20	it	it	PRON
fnp-3326	266	21	onto	onto	ADP
fnp-3326	266	22	two	two	NUM
fnp-3326	266	23	different	different	ADJ
fnp-3326	266	24	murine	murine	ADJ
fnp-3326	266	25	igg	igg	PROPN
fnp-3326	266	26	variants	variant	NOUN
fnp-3326	266	27	(	(	PUNCT
fnp-3326	266	28	i.e.	i.e.	X
fnp-3326	266	29	,	,	PUNCT
fnp-3326	266	30	migg1(v1)-mil10	migg1(v1)-mil10	PROPN
fnp-3326	266	31	and	and	CCONJ
fnp-3326	266	32	migg1(v2)-mil10	migg1(v2)-mil10	PROPN
fnp-3326	266	33	,	,	PUNCT
fnp-3326	266	34	respectively	respectively	ADV
fnp-3326	266	35	)	)	PUNCT
fnp-3326	266	36	.	.	PUNCT
fnp-3326	267	1	as	as	SCONJ
fnp-3326	267	2	described	describe	VERB
fnp-3326	267	3	above	above	ADV
fnp-3326	267	4	,	,	PUNCT
fnp-3326	267	5	dss	dss	NOUN
fnp-3326	267	6	induced	induce	VERB
fnp-3326	267	7	a	a	DET
fnp-3326	267	8	marked	mark	VERB
fnp-3326	267	9	increase	increase	NOUN
fnp-3326	267	10	in	in	ADP
fnp-3326	267	11	leukocyte	leukocyte	NOUN
fnp-3326	267	12	infiltration	infiltration	NOUN
fnp-3326	267	13	and	and	CCONJ
fnp-3326	267	14	αsyn	αsyn	NOUN
fnp-3326	267	15	accumulation	accumulation	NOUN
fnp-3326	267	16	,	,	PUNCT
fnp-3326	267	17	and	and	CCONJ
fnp-3326	267	18	we	we	PRON
fnp-3326	267	19	found	find	VERB
fnp-3326	267	20	both	both	PRON
fnp-3326	267	21	to	to	PART
fnp-3326	267	22	be	be	AUX
fnp-3326	267	23	similar	similar	ADJ
fnp-3326	267	24	in	in	ADP
fnp-3326	267	25	the	the	DET
fnp-3326	267	26	untreated	untreated	ADJ
fnp-3326	267	27	and	and	CCONJ
fnp-3326	267	28	control	control	PROPN
fnp-3326	267	29	igg	igg	PROPN
fnp-3326	267	30	treated	treat	VERB
fnp-3326	267	31	group	group	NOUN
fnp-3326	267	32	(	(	PUNCT
fnp-3326	267	33	fig	fig	NOUN
fnp-3326	267	34	.	.	PUNCT
fnp-3326	268	1	4a	4a	NUM
fnp-3326	268	2	,	,	PUNCT
fnp-3326	268	3	b	b	NOUN
fnp-3326	268	4	)	)	PUNCT
fnp-3326	268	5	.	.	PUNCT
fnp-3326	269	1	in	in	ADP
fnp-3326	269	2	contrast	contrast	NOUN
fnp-3326	269	3	,	,	PUNCT
fnp-3326	269	4	both	both	CCONJ
fnp-3326	269	5	migg1(v1)-mil10	migg1(v1)-mil10	PROPN
fnp-3326	269	6	and	and	CCONJ
fnp-3326	269	7	migg1(v2)-mil10	migg1(v2)-mil10	PROPN
fnp-3326	269	8	significantly	significantly	ADV
fnp-3326	269	9	reduced	reduce	VERB
fnp-3326	269	10	leukocyte	leukocyte	NOUN
fnp-3326	269	11	infiltration	infiltration	NOUN
fnp-3326	269	12	in	in	ADP
fnp-3326	269	13	mice	mouse	NOUN
fnp-3326	269	14	treated	treat	VERB
fnp-3326	269	15	with	with	ADP
fnp-3326	269	16	dss	dss	NOUN
fnp-3326	269	17	(	(	PUNCT
fnp-3326	269	18	p<0.0001	p<0.0001	NOUN
fnp-3326	269	19	,	,	PUNCT
fnp-3326	269	20	one	one	NUM
fnp-3326	269	21	-	-	PUNCT
fnp-3326	269	22	way	way	NOUN
fnp-3326	269	23	anova	anova	X
fnp-3326	269	24	with	with	ADP
fnp-3326	269	25	tukey	tukey	PROPN
fnp-3326	269	26	hsd	hsd	PROPN
fnp-3326	269	27	post	post	ADJ
fnp-3326	269	28	-	-	ADJ
fnp-3326	269	29	hoc	hoc	ADJ
fnp-3326	269	30	analysis	analysis	NOUN
fnp-3326	269	31	;	;	PUNCT
fnp-3326	269	32	fig	fig	NOUN
fnp-3326	269	33	.	.	PUNCT
fnp-3326	270	1	4a	4a	NUM
fnp-3326	270	2	,	,	PUNCT
fnp-3326	270	3	b	b	NOUN
fnp-3326	270	4	)	)	PUNCT
fnp-3326	270	5	.	.	PUNCT
fnp-3326	271	1	a	a	DET
fnp-3326	271	2	significant	significant	ADJ
fnp-3326	271	3	down	down	ADJ
fnp-3326	271	4	-	-	PUNCT
fnp-3326	271	5	regulatory	regulatory	ADJ
fnp-3326	271	6	effect	effect	NOUN
fnp-3326	271	7	of	of	ADP
fnp-3326	271	8	an	an	DET
fnp-3326	271	9	il-10	il-10	PRON
fnp-3326	271	10	treatment	treatment	NOUN
fnp-3326	271	11	on	on	ADP
fnp-3326	271	12	dss	dss	NOUN
fnp-3326	271	13	colitis	colitis	NOUN
fnp-3326	271	14	induced	induce	VERB
fnp-3326	271	15	accumulation	accumulation	NOUN
fnp-3326	271	16	of	of	ADP
fnp-3326	271	17	human	human	ADJ
fnp-3326	271	18	αsyn	αsyn	NOUN
fnp-3326	271	19	in	in	ADP
fnp-3326	271	20	the	the	DET
fnp-3326	271	21	submucosal	submucosal	NOUN
fnp-3326	271	22	plexus	plexus	NOUN
fnp-3326	271	23	was	be	AUX
fnp-3326	271	24	only	only	ADV
fnp-3326	271	25	observed	observe	VERB
fnp-3326	271	26	with	with	ADP
fnp-3326	271	27	migg1(v2)-mil10	migg1(v2)-mil10	PROPN
fnp-3326	271	28	(	(	PUNCT
fnp-3326	271	29	p=0.02	p=0.02	NOUN
fnp-3326	271	30	,	,	PUNCT
fnp-3326	271	31	one	one	NUM
fnp-3326	271	32	-	-	PUNCT
fnp-3326	271	33	way	way	NOUN
fnp-3326	271	34	anova	anova	X
fnp-3326	271	35	with	with	ADP
fnp-3326	271	36	tukey	tukey	PROPN
fnp-3326	271	37	hsd	hsd	PROPN
fnp-3326	271	38	post	post	ADJ
fnp-3326	271	39	-	-	ADJ
fnp-3326	271	40	hoc	hoc	ADJ
fnp-3326	271	41	analysis	analysis	NOUN
fnp-3326	271	42	;	;	PUNCT
fnp-3326	271	43	fig	fig	NOUN
fnp-3326	271	44	.	.	PUNCT
fnp-3326	272	1	4b	4b	PROPN
fnp-3326	272	2	)	)	PUNCT
fnp-3326	272	3	.	.	PUNCT
fnp-3326	273	1	this	this	DET
fnp-3326	273	2	effect	effect	NOUN
fnp-3326	273	3	by	by	ADP
fnp-3326	273	4	migg1(v2)-mil10	migg1(v2)-mil10	PROPN
fnp-3326	273	5	on	on	ADP
fnp-3326	273	6	αsyn	αsyn	ADJ
fnp-3326	273	7	levels	level	NOUN
fnp-3326	273	8	was	be	AUX
fnp-3326	273	9	accompanied	accompany	VERB
fnp-3326	273	10	by	by	ADP
fnp-3326	273	11	detectable	detectable	ADJ
fnp-3326	273	12	serum	serum	NOUN
fnp-3326	273	13	levels	level	NOUN
fnp-3326	273	14	of	of	ADP
fnp-3326	273	15	migg1(v2)-mil10	migg1(v2)-mil10	PROPN
fnp-3326	273	16	at	at	ADP
fnp-3326	273	17	the	the	DET
fnp-3326	273	18	end	end	NOUN
fnp-3326	273	19	of	of	ADP
fnp-3326	273	20	the	the	DET
fnp-3326	273	21	in	in	ADP
fnp-3326	273	22	vivo	vivo	NOUN
fnp-3326	273	23	phase	phase	NOUN
fnp-3326	273	24	,	,	PUNCT
fnp-3326	273	25	whereas	whereas	SCONJ
fnp-3326	273	26	migg1(v1)-mil10	migg1(v1)-mil10	PROPN
fnp-3326	273	27	was	be	AUX
fnp-3326	273	28	no	no	ADV
fnp-3326	273	29	longer	long	ADV
fnp-3326	273	30	detectable	detectable	ADJ
fnp-3326	273	31	at	at	ADP
fnp-3326	273	32	that	that	DET
fnp-3326	273	33	point	point	NOUN
fnp-3326	273	34	(	(	PUNCT
fnp-3326	273	35	fig	fig	NOUN
fnp-3326	273	36	.	.	PUNCT
fnp-3326	274	1	4c	4c	NOUN
fnp-3326	274	2	)	)	PUNCT
fnp-3326	274	3	.	.	PUNCT
fnp-3326	275	1	this	this	PRON
fnp-3326	275	2	indicates	indicate	VERB
fnp-3326	275	3	that	that	SCONJ
fnp-3326	275	4	although	although	SCONJ
fnp-3326	275	5	both	both	DET
fnp-3326	275	6	forms	form	NOUN
fnp-3326	275	7	of	of	ADP
fnp-3326	275	8	il-10	il-10	NOUN
fnp-3326	275	9	have	have	VERB
fnp-3326	275	10	a	a	DET
fnp-3326	275	11	down	down	ADJ
fnp-3326	275	12	-	-	PUNCT
fnp-3326	275	13	regulatory	regulatory	ADJ
fnp-3326	275	14	effect	effect	NOUN
fnp-3326	275	15	on	on	ADP
fnp-3326	275	16	leukocyte	leukocyte	ADJ
fnp-3326	275	17	infiltration	infiltration	NOUN
fnp-3326	275	18	,	,	PUNCT
fnp-3326	275	19	a	a	DET
fnp-3326	275	20	sustained	sustained	ADJ
fnp-3326	275	21	pharmacological	pharmacological	ADJ
fnp-3326	275	22	exposure	exposure	NOUN
fnp-3326	275	23	of	of	ADP
fnp-3326	275	24	il-10	il-10	PRON
fnp-3326	275	25	may	may	AUX
fnp-3326	275	26	be	be	AUX
fnp-3326	275	27	required	require	VERB
fnp-3326	275	28	for	for	ADP
fnp-3326	275	29	reducing	reduce	VERB
fnp-3326	275	30	αsyn	αsyn	ADJ
fnp-3326	275	31	accumulation	accumulation	NOUN
fnp-3326	275	32	.	.	PUNCT
fnp-3326	276	1	these	these	DET
fnp-3326	276	2	results	result	NOUN
fnp-3326	276	3	highlight	highlight	VERB
fnp-3326	276	4	an	an	DET
fnp-3326	276	5	important	important	ADJ
fnp-3326	276	6	role	role	NOUN
fnp-3326	276	7	for	for	ADP
fnp-3326	276	8	the	the	DET
fnp-3326	276	9	il-10	il-10	PRON
fnp-3326	276	10	pathway	pathway	NOUN
fnp-3326	276	11	in	in	ADP
fnp-3326	276	12	keeping	keep	VERB
fnp-3326	276	13	αsyn	αsyn	ADJ
fnp-3326	276	14	accumulation	accumulation	NOUN
fnp-3326	276	15	at	at	ADP
fnp-3326	276	16	a	a	DET
fnp-3326	276	17	reduced	reduced	ADJ
fnp-3326	276	18	level	level	NOUN
fnp-3326	276	19	throughout	throughout	ADP
fnp-3326	276	20	the	the	DET
fnp-3326	276	21	course	course	NOUN
fnp-3326	276	22	of	of	ADP
fnp-3326	276	23	experimental	experimental	ADJ
fnp-3326	276	24	ibd	ibd	NOUN
fnp-3326	276	25	.	.	PUNCT
fnp-3326	277	1	together	together	ADV
fnp-3326	277	2	,	,	PUNCT
fnp-3326	277	3	our	our	PRON
fnp-3326	277	4	observations	observation	NOUN
fnp-3326	277	5	by	by	ADP
fnp-3326	277	6	genetic	genetic	ADJ
fnp-3326	277	7	(	(	PUNCT
fnp-3326	277	8	i.e.	i.e.	X
fnp-3326	277	9	,	,	PUNCT
fnp-3326	277	10	cx3cr1	cx3cr1	NOUN
fnp-3326	277	11	-	-	ADJ
fnp-3326	277	12	cx3cl1	cx3cl1	ADJ
fnp-3326	277	13	axis	axis	NOUN
fnp-3326	277	14	)	)	PUNCT
fnp-3326	277	15	and	and	CCONJ
fnp-3326	277	16	pharmacological	pharmacological	ADJ
fnp-3326	277	17	modulation	modulation	NOUN
fnp-3326	277	18	(	(	PUNCT
fnp-3326	277	19	i.e.	i.e.	X
fnp-3326	277	20	,	,	PUNCT
fnp-3326	277	21	il-10	il-10	PRON
fnp-3326	277	22	)	)	PUNCT
fnp-3326	277	23	of	of	ADP
fnp-3326	277	24	dss	dss	NOUN
fnp-3326	277	25	colitis	colitis	NOUN
fnp-3326	277	26	corroborate	corroborate	VERB
fnp-3326	277	27	an	an	DET
fnp-3326	277	28	important	important	ADJ
fnp-3326	277	29	role	role	NOUN
fnp-3326	277	30	for	for	ADP
fnp-3326	277	31	monocyte	monocyte	NOUN
fnp-3326	277	32	/	/	SYM
fnp-3326	277	33	macrophage	macrophage	ADJ
fnp-3326	277	34	pathways	pathway	NOUN
fnp-3326	277	35	in	in	ADP
fnp-3326	277	36	the	the	DET
fnp-3326	277	37	development	development	NOUN
fnp-3326	277	38	of	of	ADP
fnp-3326	277	39	αsyn	αsyn	ADJ
fnp-3326	277	40	accumulation	accumulation	NOUN
fnp-3326	277	41	in	in	ADP
fnp-3326	277	42	the	the	DET
fnp-3326	277	43	ens	ens	NOUN
fnp-3326	277	44	of	of	ADP
fnp-3326	277	45	the	the	DET
fnp-3326	277	46	colon	colon	NOUN
fnp-3326	277	47	.	.	PUNCT
fnp-3326	278	1	fig	fig	NOUN
fnp-3326	278	2	.	.	PUNCT
fnp-3326	279	1	4	4	NUM
fnp-3326	279	2	systemic	systemic	ADJ
fnp-3326	279	3	il-10	il-10	NOUN
fnp-3326	279	4	ameliorates	ameliorate	VERB
fnp-3326	279	5	dss	dss	NOUN
fnp-3326	279	6	colitis	colitis	NOUN
fnp-3326	279	7	and	and	CCONJ
fnp-3326	279	8	slightly	slightly	ADV
fnp-3326	279	9	reduces	reduce	VERB
fnp-3326	279	10	associated	associated	ADJ
fnp-3326	279	11	local	local	ADJ
fnp-3326	279	12	αsyn	αsyn	ADJ
fnp-3326	279	13	accumulation	accumulation	NOUN
fnp-3326	279	14	in	in	ADP
fnp-3326	279	15	(	(	PUNCT
fnp-3326	279	16	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	279	17	transgenic	transgenic	NOUN
fnp-3326	279	18	mice	mouse	NOUN
fnp-3326	279	19	.	.	PUNCT
fnp-3326	280	1	two	two	NUM
fnp-3326	280	2	different	different	ADJ
fnp-3326	280	3	recombinantly	recombinantly	ADV
fnp-3326	280	4	engineered	engineer	VERB
fnp-3326	280	5	and	and	CCONJ
fnp-3326	280	6	murine	murine	ADJ
fnp-3326	280	7	igg1	igg1	NOUN
fnp-3326	280	8	-	-	PUNCT
fnp-3326	280	9	fused	fuse	VERB
fnp-3326	280	10	forms	form	NOUN
fnp-3326	280	11	of	of	ADP
fnp-3326	280	12	murine	murine	ADJ
fnp-3326	280	13	il-10	il-10	X
fnp-3326	280	14	(	(	PUNCT
fnp-3326	280	15	migg1(v1)-mil10	migg1(v1)-mil10	PROPN
fnp-3326	280	16	and	and	CCONJ
fnp-3326	280	17	migg1(v2)-mil10	migg1(v2)-mil10	PROPN
fnp-3326	280	18	)	)	PUNCT
fnp-3326	280	19	were	be	AUX
fnp-3326	280	20	administered	administer	VERB
fnp-3326	280	21	(	(	PUNCT
fnp-3326	280	22	150	150	NUM
fnp-3326	280	23	µg	µg	NOUN
fnp-3326	280	24	per	per	ADP
fnp-3326	280	25	mouse	mouse	NOUN
fnp-3326	280	26	i.p	i.p	PROPN
fnp-3326	280	27	.	.	PROPN
fnp-3326	280	28	)	)	PUNCT
fnp-3326	280	29	at	at	ADP
fnp-3326	280	30	the	the	DET
fnp-3326	280	31	beginning	beginning	NOUN
fnp-3326	280	32	of	of	ADP
fnp-3326	280	33	the	the	DET
fnp-3326	280	34	acute	acute	ADJ
fnp-3326	280	35	dss	dss	NOUN
fnp-3326	280	36	paradigm	paradigm	NOUN
fnp-3326	280	37	(	(	PUNCT
fnp-3326	280	38	5	5	NUM
fnp-3326	280	39	%	%	NOUN
fnp-3326	280	40	)	)	PUNCT
fnp-3326	280	41	in	in	ADP
fnp-3326	280	42	(	(	PUNCT
fnp-3326	280	43	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	280	44	transgenic	transgenic	NOUN
fnp-3326	280	45	mice	mouse	NOUN
fnp-3326	280	46	.	.	PUNCT
fnp-3326	281	1	vehicle	vehicle	NOUN
fnp-3326	281	2	and	and	CCONJ
fnp-3326	281	3	the	the	DET
fnp-3326	281	4	migg1(v1	migg1(v1	PROPN
fnp-3326	281	5	)	)	PUNCT
fnp-3326	281	6	alone	alone	ADV
fnp-3326	281	7	served	serve	VERB
fnp-3326	281	8	as	as	ADP
fnp-3326	281	9	untreated	untreated	ADJ
fnp-3326	281	10	controls	control	NOUN
fnp-3326	281	11	.	.	PUNCT
fnp-3326	282	1	a	a	DET
fnp-3326	282	2	leukocyte	leukocyte	NOUN
fnp-3326	282	3	infiltration	infiltration	NOUN
fnp-3326	282	4	was	be	AUX
fnp-3326	282	5	assessed	assess	VERB
fnp-3326	282	6	by	by	ADP
fnp-3326	282	7	visual	visual	ADJ
fnp-3326	282	8	scoring	scoring	NOUN
fnp-3326	282	9	and	and	CCONJ
fnp-3326	282	10	(	(	PUNCT
fnp-3326	282	11	b	b	NOUN
fnp-3326	282	12	)	)	PUNCT
fnp-3326	282	13	inclusion	inclusion	NOUN
fnp-3326	282	14	features	feature	NOUN
fnp-3326	282	15	of	of	ADP
fnp-3326	282	16	αsyn	αsyn	NOUN
fnp-3326	282	17	were	be	AUX
fnp-3326	282	18	stereologically	stereologically	ADV
fnp-3326	282	19	and	and	CCONJ
fnp-3326	282	20	semi	semi	ADJ
fnp-3326	282	21	-	-	ADJ
fnp-3326	282	22	automatically	automatically	ADV
fnp-3326	282	23	quantified	quantify	VERB
fnp-3326	282	24	and	and	CCONJ
fnp-3326	282	25	result	result	VERB
fnp-3326	282	26	log	log	NOUN
fnp-3326	282	27	scaled	scale	VERB
fnp-3326	282	28	for	for	ADP
fnp-3326	282	29	statistical	statistical	ADJ
fnp-3326	282	30	analysis	analysis	NOUN
fnp-3326	282	31	.	.	PUNCT
fnp-3326	283	1	both	both	CCONJ
fnp-3326	283	2	the	the	DET
fnp-3326	283	3	vehicle	vehicle	NOUN
fnp-3326	283	4	group	group	NOUN
fnp-3326	283	5	and	and	CCONJ
fnp-3326	283	6	the	the	DET
fnp-3326	283	7	migg1(v1	migg1(v1	PROPN
fnp-3326	283	8	)	)	PUNCT
fnp-3326	283	9	group	group	NOUN
fnp-3326	283	10	had	have	VERB
fnp-3326	283	11	similar	similar	ADJ
fnp-3326	283	12	levels	level	NOUN
fnp-3326	283	13	of	of	ADP
fnp-3326	283	14	leukocyte	leukocyte	NOUN
fnp-3326	283	15	infiltration	infiltration	NOUN
fnp-3326	283	16	and	and	CCONJ
fnp-3326	283	17	αsyn	αsyn	ADJ
fnp-3326	283	18	inclusions	inclusion	NOUN
fnp-3326	283	19	and	and	CCONJ
fnp-3326	283	20	were	be	AUX
fnp-3326	283	21	merged	merge	VERB
fnp-3326	283	22	for	for	ADP
fnp-3326	283	23	the	the	DET
fnp-3326	283	24	statistical	statistical	ADJ
fnp-3326	283	25	analysis	analysis	NOUN
fnp-3326	283	26	to	to	PART
fnp-3326	283	27	compare	compare	VERB
fnp-3326	283	28	with	with	ADP
fnp-3326	283	29	the	the	DET
fnp-3326	283	30	il-10	il-10	ADV
fnp-3326	283	31	treated	treat	VERB
fnp-3326	283	32	groups	group	NOUN
fnp-3326	283	33	.	.	PUNCT
fnp-3326	284	1	both	both	DET
fnp-3326	284	2	forms	form	NOUN
fnp-3326	284	3	of	of	ADP
fnp-3326	284	4	il-10	il-10	PRON
fnp-3326	284	5	ameliorated	ameliorate	VERB
fnp-3326	284	6	leukocyte	leukocyte	NOUN
fnp-3326	284	7	infiltration	infiltration	NOUN
fnp-3326	284	8	whereas	whereas	SCONJ
fnp-3326	284	9	migg1(v2)-mil10	migg1(v2)-mil10	PROPN
fnp-3326	284	10	also	also	ADV
fnp-3326	284	11	blocked	block	VERB
fnp-3326	284	12	the	the	DET
fnp-3326	284	13	appearance	appearance	NOUN
fnp-3326	284	14	of	of	ADP
fnp-3326	284	15	αsyn	αsyn	ADJ
fnp-3326	284	16	inclusions	inclusion	NOUN
fnp-3326	284	17	significantly	significantly	ADV
fnp-3326	284	18	(	(	PUNCT
fnp-3326	284	19	n	n	NOUN
fnp-3326	284	20	=	=	SYM
fnp-3326	284	21	3	3	NUM
fnp-3326	284	22	-	-	SYM
fnp-3326	284	23	6	6	NUM
fnp-3326	284	24	per	per	ADP
fnp-3326	284	25	group	group	NOUN
fnp-3326	284	26	;	;	PUNCT
fnp-3326	284	27	mean	mean	VERB
fnp-3326	284	28	and	and	CCONJ
fnp-3326	284	29	s.e.m	s.e.m	NOUN
fnp-3326	284	30	.	.	PROPN
fnp-3326	284	31	;	;	PUNCT
fnp-3326	284	32	one	one	NUM
fnp-3326	284	33	-	-	PUNCT
fnp-3326	284	34	way	way	NOUN
fnp-3326	284	35	anova	anova	X
fnp-3326	284	36	and	and	CCONJ
fnp-3326	284	37	tukey	tukey	PROPN
fnp-3326	284	38	post	post	X
fnp-3326	284	39	hoc	hoc	X
fnp-3326	284	40	test	test	NOUN
fnp-3326	284	41	)	)	PUNCT
fnp-3326	284	42	.	.	PUNCT
fnp-3326	285	1	c	c	PROPN
fnp-3326	285	2	persistent	persistent	ADJ
fnp-3326	285	3	exposure	exposure	NOUN
fnp-3326	285	4	migg1(v2)-mil10	migg1(v2)-mil10	PROPN
fnp-3326	285	5	versus	versus	ADP
fnp-3326	285	6	migg1(v1)-mil10	migg1(v1)-mil10	PROPN
fnp-3326	285	7	(	(	PUNCT
fnp-3326	285	8	lower	low	ADJ
fnp-3326	285	9	limit	limit	NOUN
fnp-3326	285	10	of	of	ADP
fnp-3326	285	11	detection	detection	NOUN
fnp-3326	285	12	is	be	AUX
fnp-3326	285	13	indicated	indicate	VERB
fnp-3326	285	14	at	at	ADP
fnp-3326	285	15	<	<	X
fnp-3326	285	16	0.234	0.234	NUM
fnp-3326	285	17	μg	μg	NOUN
fnp-3326	285	18	/	/	SYM
fnp-3326	285	19	ml	ml	NOUN
fnp-3326	285	20	)	)	PUNCT
fnp-3326	285	21	as	as	SCONJ
fnp-3326	285	22	measured	measure	VERB
fnp-3326	285	23	in	in	ADP
fnp-3326	285	24	serum	serum	NOUN
fnp-3326	285	25	at	at	ADP
fnp-3326	285	26	the	the	DET
fnp-3326	285	27	end	end	NOUN
fnp-3326	285	28	of	of	ADP
fnp-3326	285	29	the	the	DET
fnp-3326	285	30	in	in	ADP
fnp-3326	285	31	vivo	vivo	NOUN
fnp-3326	285	32	phase	phase	NOUN
fnp-3326	285	33	corresponds	correspond	VERB
fnp-3326	285	34	with	with	ADP
fnp-3326	285	35	beneficial	beneficial	ADJ
fnp-3326	285	36	treatment	treatment	NOUN
fnp-3326	285	37	effects	effect	NOUN
fnp-3326	285	38	on	on	ADP
fnp-3326	285	39	αsyn	αsyn	NOUN
fnp-3326	285	40	readout	readout	VERB
fnp-3326	285	41	observed	observe	VERB
fnp-3326	285	42	above	above	ADV
fnp-3326	285	43	.	.	PUNCT
fnp-3326	286	1	the	the	DET
fnp-3326	286	2	migg1(v1	migg1(v1	PROPN
fnp-3326	286	3	)	)	PUNCT
fnp-3326	286	4	was	be	AUX
fnp-3326	286	5	only	only	ADV
fnp-3326	286	6	measured	measure	VERB
fnp-3326	286	7	in	in	ADP
fnp-3326	286	8	two	two	NUM
fnp-3326	286	9	mice	mouse	NOUN
fnp-3326	286	10	.	.	PUNCT
fnp-3326	287	1	dss	dss	NOUN
fnp-3326	287	2	colitis	colitis	NOUN
fnp-3326	287	3	-	-	PUNCT
fnp-3326	287	4	induced	induce	VERB
fnp-3326	287	5	submucosal	submucosal	NOUN
fnp-3326	287	6	αsyn	αsyn	NOUN
fnp-3326	287	7	accumulation	accumulation	NOUN
fnp-3326	287	8	at	at	ADP
fnp-3326	287	9	a	a	DET
fnp-3326	287	10	young	young	ADJ
fnp-3326	287	11	age	age	NOUN
fnp-3326	287	12	persists	persist	VERB
fnp-3326	287	13	for	for	ADP
fnp-3326	287	14	months	month	NOUN
fnp-3326	287	15	and	and	CCONJ
fnp-3326	287	16	is	be	AUX
fnp-3326	287	17	exacerbated	exacerbate	VERB
fnp-3326	287	18	by	by	ADP
fnp-3326	287	19	lack	lack	NOUN
fnp-3326	287	20	of	of	ADP
fnp-3326	287	21	cx3cr1	cx3cr1	NOUN
fnp-3326	287	22	signaling	signal	VERB
fnp-3326	287	23	in	in	ADP
fnp-3326	287	24	humans	human	NOUN
fnp-3326	287	25	there	there	PRON
fnp-3326	287	26	is	be	VERB
fnp-3326	287	27	strong	strong	ADJ
fnp-3326	287	28	epidemiological	epidemiological	ADJ
fnp-3326	287	29	evidence	evidence	NOUN
fnp-3326	287	30	that	that	SCONJ
fnp-3326	287	31	ibd	ibd	PROPN
fnp-3326	287	32	increases	increase	VERB
fnp-3326	287	33	pd	pd	PROPN
fnp-3326	287	34	risk	risk	NOUN
fnp-3326	288	1	[	[	X
fnp-3326	288	2	33,35,37	33,35,37	X
fnp-3326	288	3	]	]	PUNCT
fnp-3326	288	4	and	and	CCONJ
fnp-3326	288	5	recent	recent	ADJ
fnp-3326	288	6	evidence	evidence	NOUN
fnp-3326	288	7	in	in	ADP
fnp-3326	288	8	crohn	crohn	PROPN
fnp-3326	288	9	’s	’s	PART
fnp-3326	288	10	disease	disease	NOUN
fnp-3326	289	1	[	[	X
fnp-3326	289	2	55	55	NUM
fnp-3326	289	3	]	]	PUNCT
fnp-3326	289	4	indicates	indicate	VERB
fnp-3326	289	5	that	that	SCONJ
fnp-3326	289	6	such	such	ADJ
fnp-3326	289	7	gut	gut	NOUN
fnp-3326	289	8	inflammatory	inflammatory	ADJ
fnp-3326	289	9	conditions	condition	NOUN
fnp-3326	289	10	are	be	AUX
fnp-3326	289	11	associated	associate	VERB
fnp-3326	289	12	with	with	ADP
fnp-3326	289	13	αsyn	αsyn	ADJ
fnp-3326	289	14	accumulation	accumulation	NOUN
fnp-3326	289	15	in	in	ADP
fnp-3326	289	16	the	the	DET
fnp-3326	289	17	ens	ens	NOUN
fnp-3326	289	18	[	[	X
fnp-3326	289	19	36	36	NUM
fnp-3326	289	20	]	]	PUNCT
fnp-3326	289	21	.	.	PUNCT
fnp-3326	290	1	in	in	ADP
fnp-3326	290	2	these	these	DET
fnp-3326	290	3	experiments	experiment	NOUN
fnp-3326	290	4	in	in	ADP
fnp-3326	290	5	mice	mouse	NOUN
fnp-3326	290	6	,	,	PUNCT
fnp-3326	290	7	we	we	PRON
fnp-3326	290	8	have	have	AUX
fnp-3326	290	9	until	until	ADP
fnp-3326	290	10	here	here	ADV
fnp-3326	290	11	established	establish	VERB
fnp-3326	290	12	and	and	CCONJ
fnp-3326	290	13	replicated	replicate	VERB
fnp-3326	290	14	,	,	PUNCT
fnp-3326	290	15	in	in	ADP
fnp-3326	290	16	different	different	ADJ
fnp-3326	290	17	setups	setup	NOUN
fnp-3326	290	18	,	,	PUNCT
fnp-3326	290	19	a	a	DET
fnp-3326	290	20	link	link	NOUN
fnp-3326	290	21	between	between	ADP
fnp-3326	290	22	modulation	modulation	NOUN
fnp-3326	290	23	of	of	ADP
fnp-3326	290	24	inflammation	inflammation	NOUN
fnp-3326	290	25	and	and	CCONJ
fnp-3326	290	26	induction	induction	NOUN
fnp-3326	290	27	of	of	ADP
fnp-3326	290	28	αsyn	αsyn	ADJ
fnp-3326	290	29	accumulation	accumulation	NOUN
fnp-3326	290	30	in	in	ADP
fnp-3326	290	31	the	the	DET
fnp-3326	290	32	ens	en	NOUN
fnp-3326	290	33	.	.	PROPN
fnp-3326	291	1	because	because	SCONJ
fnp-3326	291	2	longer	long	ADJ
fnp-3326	291	3	exposure	exposure	NOUN
fnp-3326	291	4	to	to	ADP
fnp-3326	291	5	dss	dss	NOUN
fnp-3326	291	6	(	(	PUNCT
fnp-3326	291	7	i.e.	i.e.	X
fnp-3326	291	8	,	,	PUNCT
fnp-3326	291	9	over	over	ADP
fnp-3326	291	10	several	several	ADJ
fnp-3326	291	11	weeks	week	NOUN
fnp-3326	291	12	)	)	PUNCT
fnp-3326	291	13	mimics	mimic	VERB
fnp-3326	291	14	more	more	ADV
fnp-3326	291	15	closely	closely	ADV
fnp-3326	291	16	the	the	DET
fnp-3326	291	17	chronic	chronic	ADJ
fnp-3326	291	18	nature	nature	NOUN
fnp-3326	291	19	of	of	ADP
fnp-3326	291	20	ibd	ibd	PROPN
fnp-3326	291	21	,	,	PUNCT
fnp-3326	291	22	we	we	PRON
fnp-3326	291	23	elected	elect	VERB
fnp-3326	291	24	to	to	PART
fnp-3326	291	25	explore	explore	VERB
fnp-3326	291	26	αsyn	αsyn	ADJ
fnp-3326	291	27	accumulation	accumulation	NOUN
fnp-3326	291	28	in	in	ADP
fnp-3326	291	29	the	the	DET
fnp-3326	291	30	submucosal	submucosal	NOUN
fnp-3326	291	31	plexus	plexus	NOUN
fnp-3326	291	32	of	of	ADP
fnp-3326	291	33	(	(	PUNCT
fnp-3326	291	34	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	291	35	transgenic	transgenic	NOUN
fnp-3326	291	36	mice	mouse	NOUN
fnp-3326	291	37	that	that	PRON
fnp-3326	291	38	were	be	AUX
fnp-3326	291	39	subjected	subject	VERB
fnp-3326	291	40	to	to	ADP
fnp-3326	291	41	dss	dss	NOUN
fnp-3326	291	42	colitis	colitis	NOUN
fnp-3326	291	43	in	in	ADP
fnp-3326	291	44	a	a	DET
fnp-3326	291	45	4	4	NUM
fnp-3326	291	46	-	-	PUNCT
fnp-3326	291	47	week	week	NOUN
fnp-3326	291	48	chronic	chronic	ADJ
fnp-3326	291	49	increasing	increase	VERB
fnp-3326	291	50	dose	dose	NOUN
fnp-3326	291	51	paradigm	paradigm	NOUN
fnp-3326	291	52	.	.	PUNCT
fnp-3326	292	1	in	in	ADP
fnp-3326	292	2	addition	addition	NOUN
fnp-3326	292	3	,	,	PUNCT
fnp-3326	292	4	the	the	DET
fnp-3326	292	5	dose	dose	NOUN
fnp-3326	292	6	increase	increase	NOUN
fnp-3326	292	7	with	with	ADP
fnp-3326	292	8	longer	long	ADJ
fnp-3326	292	9	water	water	NOUN
fnp-3326	292	10	intervals	interval	NOUN
fnp-3326	292	11	is	be	AUX
fnp-3326	292	12	more	more	ADV
fnp-3326	292	13	gentle	gentle	ADJ
fnp-3326	292	14	for	for	ADP
fnp-3326	292	15	the	the	DET
fnp-3326	292	16	mice	mouse	NOUN
fnp-3326	292	17	from	from	ADP
fnp-3326	292	18	an	an	DET
fnp-3326	292	19	animal	animal	NOUN
fnp-3326	292	20	welfare	welfare	NOUN
fnp-3326	292	21	perspective	perspective	NOUN
fnp-3326	292	22	.	.	PUNCT
fnp-3326	293	1	in	in	ADP
fnp-3326	293	2	order	order	NOUN
fnp-3326	293	3	to	to	PART
fnp-3326	293	4	allow	allow	VERB
fnp-3326	293	5	for	for	ADP
fnp-3326	293	6	a	a	DET
fnp-3326	293	7	full	full	ADJ
fnp-3326	293	8	recovery	recovery	NOUN
fnp-3326	293	9	from	from	ADP
fnp-3326	293	10	the	the	DET
fnp-3326	293	11	chronic	chronic	ADJ
fnp-3326	293	12	inflammation	inflammation	NOUN
fnp-3326	293	13	,	,	PUNCT
fnp-3326	293	14	we	we	PRON
fnp-3326	293	15	aged	age	VERB
fnp-3326	293	16	the	the	DET
fnp-3326	293	17	mice	mouse	NOUN
fnp-3326	293	18	for	for	ADP
fnp-3326	293	19	two	two	NUM
fnp-3326	293	20	months	month	NOUN
fnp-3326	293	21	on	on	ADP
fnp-3326	293	22	normal	normal	ADJ
fnp-3326	293	23	drinking	drinking	NOUN
fnp-3326	293	24	water	water	NOUN
fnp-3326	293	25	and	and	CCONJ
fnp-3326	293	26	analyzed	analyze	VERB
fnp-3326	293	27	them	they	PRON
fnp-3326	293	28	at	at	ADP
fnp-3326	293	29	the	the	DET
fnp-3326	293	30	age	age	NOUN
fnp-3326	293	31	of	of	ADP
fnp-3326	293	32	6	6	NUM
fnp-3326	293	33	months	month	NOUN
fnp-3326	293	34	(	(	PUNCT
fnp-3326	293	35	fig	fig	NOUN
fnp-3326	293	36	.	.	PUNCT
fnp-3326	294	1	1c	1c	NOUN
fnp-3326	294	2	)	)	PUNCT
fnp-3326	294	3	.	.	PUNCT
fnp-3326	295	1	at	at	ADP
fnp-3326	295	2	this	this	DET
fnp-3326	295	3	point	point	NOUN
fnp-3326	295	4	we	we	PRON
fnp-3326	295	5	wanted	want	VERB
fnp-3326	295	6	again	again	ADV
fnp-3326	295	7	to	to	PART
fnp-3326	295	8	explore	explore	VERB
fnp-3326	295	9	the	the	DET
fnp-3326	295	10	effect	effect	NOUN
fnp-3326	295	11	of	of	ADP
fnp-3326	295	12	modulating	modulate	VERB
fnp-3326	295	13	monocytes	monocyte	NOUN
fnp-3326	295	14	/	/	SYM
fnp-3326	295	15	macrophages	macrophage	NOUN
fnp-3326	295	16	in	in	ADP
fnp-3326	295	17	this	this	DET
fnp-3326	295	18	chronic	chronic	NOUN
fnp-3326	295	19	setting	set	VERB
fnp-3326	295	20	and	and	CCONJ
fnp-3326	295	21	added	add	VERB
fnp-3326	295	22	an	an	DET
fnp-3326	295	23	experimental	experimental	ADJ
fnp-3326	295	24	arm	arm	NOUN
fnp-3326	295	25	with	with	ADP
fnp-3326	295	26	(	(	PUNCT
fnp-3326	295	27	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	295	28	transgenic	transgenic	NOUN
fnp-3326	295	29	mice	mouse	NOUN
fnp-3326	295	30	lacking	lack	VERB
fnp-3326	295	31	cx3cr1	cx3cr1	NOUN
fnp-3326	295	32	.	.	PUNCT
fnp-3326	296	1	as	as	SCONJ
fnp-3326	296	2	expected	expect	VERB
fnp-3326	296	3	,	,	PUNCT
fnp-3326	296	4	after	after	ADP
fnp-3326	296	5	2	2	NUM
fnp-3326	296	6	months	month	NOUN
fnp-3326	296	7	of	of	ADP
fnp-3326	296	8	recovery	recovery	NOUN
fnp-3326	296	9	,	,	PUNCT
fnp-3326	296	10	the	the	DET
fnp-3326	296	11	area	area	NOUN
fnp-3326	296	12	that	that	PRON
fnp-3326	296	13	is	be	AUX
fnp-3326	296	14	usually	usually	ADV
fnp-3326	296	15	extensively	extensively	ADV
fnp-3326	296	16	covered	cover	VERB
fnp-3326	296	17	by	by	ADP
fnp-3326	296	18	leukocytes	leukocyte	NOUN
fnp-3326	296	19	in	in	ADP
fnp-3326	296	20	the	the	DET
fnp-3326	296	21	submucosal	submucosal	NOUN
fnp-3326	296	22	plexus	plexus	NOUN
fnp-3326	296	23	of	of	ADP
fnp-3326	296	24	the	the	DET
fnp-3326	296	25	acute	acute	ADJ
fnp-3326	296	26	dss	dss	NOUN
fnp-3326	296	27	paradigm	paradigm	NOUN
fnp-3326	296	28	had	have	AUX
fnp-3326	296	29	returned	return	VERB
fnp-3326	296	30	to	to	ADP
fnp-3326	296	31	normal	normal	ADJ
fnp-3326	296	32	levels	level	NOUN
fnp-3326	296	33	following	follow	VERB
fnp-3326	296	34	the	the	DET
fnp-3326	296	35	two	two	NUM
fnp-3326	296	36	-	-	PUNCT
fnp-3326	296	37	month	month	NOUN
fnp-3326	296	38	recovery	recovery	NOUN
fnp-3326	296	39	period	period	NOUN
fnp-3326	296	40	(	(	PUNCT
fnp-3326	296	41	suppl	suppl	PROPN
fnp-3326	296	42	.	.	PUNCT
fnp-3326	296	43	fig	fig	PROPN
fnp-3326	296	44	.	.	PUNCT
fnp-3326	297	1	4a	4a	NUM
fnp-3326	297	2	)	)	PUNCT
fnp-3326	297	3	.	.	PUNCT
fnp-3326	298	1	remarkably	remarkably	ADV
fnp-3326	298	2	,	,	PUNCT
fnp-3326	298	3	however	however	ADV
fnp-3326	298	4	,	,	PUNCT
fnp-3326	298	5	the	the	DET
fnp-3326	298	6	area	area	NOUN
fnp-3326	298	7	containing	contain	VERB
fnp-3326	298	8	αsyn	αsyn	ADJ
fnp-3326	298	9	inclusions	inclusion	NOUN
fnp-3326	298	10	in	in	ADP
fnp-3326	298	11	the	the	DET
fnp-3326	298	12	ganglia	ganglia	NOUN
fnp-3326	298	13	of	of	ADP
fnp-3326	298	14	the	the	DET
fnp-3326	298	15	submucosal	submucosal	NOUN
fnp-3326	298	16	plexus	plexus	NOUN
fnp-3326	298	17	was	be	AUX
fnp-3326	298	18	still	still	ADV
fnp-3326	298	19	almost	almost	ADV
fnp-3326	298	20	doubled	double	VERB
fnp-3326	298	21	when	when	SCONJ
fnp-3326	298	22	compared	compare	VERB
fnp-3326	298	23	to	to	ADP
fnp-3326	298	24	αsyn	αsyn	ADJ
fnp-3326	298	25	transgenic	transgenic	NOUN
fnp-3326	298	26	mice	mouse	NOUN
fnp-3326	298	27	that	that	PRON
fnp-3326	298	28	were	be	AUX
fnp-3326	298	29	not	not	PART
fnp-3326	298	30	exposed	expose	VERB
fnp-3326	298	31	to	to	ADP
fnp-3326	298	32	dss	dss	NOUN
fnp-3326	298	33	,	,	PUNCT
fnp-3326	298	34	and	and	CCONJ
fnp-3326	298	35	this	this	PRON
fnp-3326	298	36	was	be	AUX
fnp-3326	298	37	exacerbated	exacerbate	VERB
fnp-3326	298	38	in	in	ADP
fnp-3326	298	39	αsyn	αsyn	ADJ
fnp-3326	298	40	transgenic	transgenic	NOUN
fnp-3326	298	41	mice	mouse	NOUN
fnp-3326	298	42	deficient	deficient	ADJ
fnp-3326	298	43	for	for	ADP
fnp-3326	298	44	cx3cr1	cx3cr1	PROPN
fnp-3326	298	45	(	(	PUNCT
fnp-3326	298	46	suppl	suppl	PROPN
fnp-3326	298	47	.	.	PUNCT
fnp-3326	298	48	fig	fig	PROPN
fnp-3326	298	49	.	.	PUNCT
fnp-3326	299	1	4b	4b	PROPN
fnp-3326	299	2	)	)	PUNCT
fnp-3326	299	3	.	.	PUNCT
fnp-3326	300	1	the	the	DET
fnp-3326	300	2	finding	finding	NOUN
fnp-3326	300	3	in	in	ADP
fnp-3326	300	4	the	the	DET
fnp-3326	300	5	αsyn	αsyn	ADJ
fnp-3326	300	6	transgenic	transgenic	NOUN
fnp-3326	300	7	mice	mouse	NOUN
fnp-3326	300	8	suggests	suggest	VERB
fnp-3326	300	9	that	that	SCONJ
fnp-3326	300	10	accumulation	accumulation	NOUN
fnp-3326	300	11	of	of	ADP
fnp-3326	300	12	αsyn	αsyn	NOUN
fnp-3326	300	13	is	be	AUX
fnp-3326	300	14	not	not	PART
fnp-3326	300	15	a	a	DET
fnp-3326	300	16	transient	transient	ADJ
fnp-3326	300	17	effect	effect	NOUN
fnp-3326	300	18	or	or	CCONJ
fnp-3326	300	19	response	response	NOUN
fnp-3326	300	20	.	.	PUNCT
fnp-3326	301	1	in	in	ADP
fnp-3326	301	2	addition	addition	NOUN
fnp-3326	301	3	,	,	PUNCT
fnp-3326	301	4	modulation	modulation	NOUN
fnp-3326	301	5	of	of	ADP
fnp-3326	301	6	monocytes	monocyte	NOUN
fnp-3326	301	7	/	/	SYM
fnp-3326	301	8	macrophages	macrophage	NOUN
fnp-3326	301	9	by	by	ADP
fnp-3326	301	10	down	down	ADV
fnp-3326	301	11	-	-	PUNCT
fnp-3326	301	12	regulating	regulate	VERB
fnp-3326	301	13	the	the	DET
fnp-3326	301	14	cx3cr1	cx3cr1	NOUN
fnp-3326	301	15	-	-	PUNCT
fnp-3326	301	16	cx3cl1	cx3cl1	ADJ
fnp-3326	301	17	axis	axis	NOUN
fnp-3326	301	18	contributes	contribute	VERB
fnp-3326	301	19	to	to	PART
fnp-3326	301	20	aggravation	aggravation	NOUN
fnp-3326	301	21	of	of	ADP
fnp-3326	301	22	this	this	DET
fnp-3326	301	23	accumulation	accumulation	NOUN
fnp-3326	301	24	.	.	PUNCT
fnp-3326	302	1	experimental	experimental	ADJ
fnp-3326	302	2	dss	dss	NOUN
fnp-3326	302	3	colitis	colitis	NOUN
fnp-3326	302	4	-	-	PUNCT
fnp-3326	302	5	induced	induce	VERB
fnp-3326	302	6	at	at	ADP
fnp-3326	302	7	a	a	DET
fnp-3326	302	8	young	young	ADJ
fnp-3326	302	9	age	age	NOUN
fnp-3326	302	10	exacerbates	exacerbate	VERB
fnp-3326	302	11	αsyn	αsyn	ADJ
fnp-3326	302	12	brain	brain	NOUN
fnp-3326	302	13	pathology	pathology	NOUN
fnp-3326	302	14	and	and	CCONJ
fnp-3326	302	15	dopaminergic	dopaminergic	ADJ
fnp-3326	302	16	neuron	neuron	NOUN
fnp-3326	302	17	loss	loss	NOUN
fnp-3326	302	18	in	in	ADP
fnp-3326	302	19	old	old	ADJ
fnp-3326	302	20	αsyn	αsyn	ADJ
fnp-3326	302	21	transgenic	transgenic	NOUN
fnp-3326	302	22	mice	mouse	NOUN
fnp-3326	302	23	at	at	ADP
fnp-3326	302	24	this	this	DET
fnp-3326	302	25	point	point	NOUN
fnp-3326	302	26	,	,	PUNCT
fnp-3326	302	27	we	we	PRON
fnp-3326	302	28	have	have	AUX
fnp-3326	302	29	established	establish	VERB
fnp-3326	302	30	and	and	CCONJ
fnp-3326	302	31	repeatedly	repeatedly	ADV
fnp-3326	302	32	demonstrated	demonstrate	VERB
fnp-3326	302	33	that	that	DET
fnp-3326	302	34	modulation	modulation	NOUN
fnp-3326	302	35	of	of	ADP
fnp-3326	302	36	inflammatory	inflammatory	ADJ
fnp-3326	302	37	mechanisms	mechanism	NOUN
fnp-3326	302	38	in	in	ADP
fnp-3326	302	39	experimental	experimental	ADJ
fnp-3326	302	40	colitis	colitis	NOUN
fnp-3326	302	41	induced	induce	VERB
fnp-3326	302	42	by	by	ADP
fnp-3326	302	43	acute	acute	ADJ
fnp-3326	302	44	and	and	CCONJ
fnp-3326	302	45	chronic	chronic	ADJ
fnp-3326	302	46	dss	dss	NOUN
fnp-3326	302	47	administration	administration	NOUN
fnp-3326	302	48	is	be	AUX
fnp-3326	302	49	causatively	causatively	ADV
fnp-3326	302	50	linked	link	VERB
fnp-3326	302	51	to	to	ADP
fnp-3326	302	52	induction	induction	NOUN
fnp-3326	302	53	and	and	CCONJ
fnp-3326	302	54	persistence	persistence	NOUN
fnp-3326	302	55	of	of	ADP
fnp-3326	302	56	intracellular	intracellular	ADJ
fnp-3326	302	57	αsyn	αsyn	ADJ
fnp-3326	302	58	inclusions	inclusion	NOUN
fnp-3326	302	59	in	in	ADP
fnp-3326	302	60	the	the	DET
fnp-3326	302	61	ens	ens	NOUN
fnp-3326	302	62	of	of	ADP
fnp-3326	302	63	young	young	ADJ
fnp-3326	302	64	adult	adult	NOUN
fnp-3326	302	65	mice	mouse	NOUN
fnp-3326	302	66	.	.	PUNCT
fnp-3326	303	1	the	the	DET
fnp-3326	303	2	previously	previously	ADV
fnp-3326	303	3	highlighted	highlight	VERB
fnp-3326	303	4	hypothesis	hypothesis	NOUN
fnp-3326	303	5	by	by	ADP
fnp-3326	303	6	braak	braak	NOUN
fnp-3326	303	7	and	and	CCONJ
fnp-3326	303	8	colleagues	colleague	NOUN
fnp-3326	303	9	associates	associate	VERB
fnp-3326	303	10	αsyn	αsyn	ADJ
fnp-3326	303	11	brain	brain	NOUN
fnp-3326	303	12	pathology	pathology	NOUN
fnp-3326	303	13	in	in	ADP
fnp-3326	303	14	pd	pd	PROPN
fnp-3326	303	15	with	with	ADP
fnp-3326	303	16	αsyn	αsyn	PROPN
fnp-3326	303	17	pathology	pathology	NOUN
fnp-3326	303	18	in	in	ADP
fnp-3326	303	19	the	the	DET
fnp-3326	303	20	ens	en	NOUN
fnp-3326	303	21	earlier	early	ADV
fnp-3326	303	22	in	in	ADP
fnp-3326	303	23	life	life	NOUN
fnp-3326	303	24	[	[	X
fnp-3326	303	25	3,56	3,56	X
fnp-3326	303	26	]	]	PUNCT
fnp-3326	303	27	.	.	PUNCT
fnp-3326	304	1	to	to	PART
fnp-3326	304	2	assess	assess	VERB
fnp-3326	304	3	development	development	NOUN
fnp-3326	304	4	of	of	ADP
fnp-3326	304	5	brain	brain	NOUN
fnp-3326	304	6	αsyn	αsyn	NOUN
fnp-3326	304	7	pathology	pathology	NOUN
fnp-3326	304	8	and	and	CCONJ
fnp-3326	304	9	to	to	PART
fnp-3326	304	10	link	link	VERB
fnp-3326	304	11	it	it	PRON
fnp-3326	304	12	to	to	ADP
fnp-3326	304	13	ibd	ibd	PROPN
fnp-3326	304	14	risk	risk	NOUN
fnp-3326	304	15	,	,	PUNCT
fnp-3326	304	16	we	we	PRON
fnp-3326	304	17	exposed	expose	VERB
fnp-3326	304	18	3	3	NUM
fnp-3326	304	19	-	-	PUNCT
fnp-3326	304	20	month	month	NOUN
fnp-3326	304	21	-	-	PUNCT
fnp-3326	304	22	old	old	ADJ
fnp-3326	304	23	hemizygous	hemizygous	ADJ
fnp-3326	304	24	(	(	PUNCT
fnp-3326	304	25	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	304	26	transgenic	transgenic	NOUN
fnp-3326	304	27	mice	mouse	NOUN
fnp-3326	304	28	to	to	ADP
fnp-3326	304	29	a	a	DET
fnp-3326	304	30	chronic	chronic	ADJ
fnp-3326	304	31	increasing	increase	VERB
fnp-3326	304	32	dose	dose	NOUN
fnp-3326	304	33	dss	dss	NOUN
fnp-3326	304	34	paradigm	paradigm	NOUN
fnp-3326	304	35	or	or	CCONJ
fnp-3326	304	36	normal	normal	ADJ
fnp-3326	304	37	drinking	drinking	NOUN
fnp-3326	304	38	water	water	NOUN
fnp-3326	304	39	and	and	CCONJ
fnp-3326	304	40	after	after	ADP
fnp-3326	304	41	23	23	NUM
fnp-3326	304	42	days	day	NOUN
fnp-3326	304	43	returned	return	VERB
fnp-3326	304	44	all	all	DET
fnp-3326	304	45	mice	mouse	NOUN
fnp-3326	304	46	to	to	ADP
fnp-3326	304	47	normal	normal	ADJ
fnp-3326	304	48	drinking	drinking	NOUN
fnp-3326	304	49	water	water	NOUN
fnp-3326	304	50	until	until	ADP
fnp-3326	304	51	sacrifice	sacrifice	NOUN
fnp-3326	304	52	several	several	ADJ
fnp-3326	304	53	months	month	NOUN
fnp-3326	304	54	later	later	ADV
fnp-3326	304	55	(	(	PUNCT
fnp-3326	304	56	fig	fig	NOUN
fnp-3326	304	57	.	.	PUNCT
fnp-3326	305	1	1c	1c	NOUN
fnp-3326	305	2	)	)	PUNCT
fnp-3326	305	3	.	.	PUNCT
fnp-3326	306	1	we	we	PRON
fnp-3326	306	2	chose	choose	VERB
fnp-3326	306	3	to	to	PART
fnp-3326	306	4	use	use	VERB
fnp-3326	306	5	the	the	DET
fnp-3326	306	6	αsyn	αsyn	ADJ
fnp-3326	306	7	transgenic	transgenic	NOUN
fnp-3326	306	8	model	model	NOUN
fnp-3326	306	9	rather	rather	ADV
fnp-3326	306	10	than	than	ADP
fnp-3326	306	11	wild	wild	ADJ
fnp-3326	306	12	type	type	NOUN
fnp-3326	306	13	mice	mouse	NOUN
fnp-3326	306	14	for	for	ADP
fnp-3326	306	15	this	this	DET
fnp-3326	306	16	study	study	NOUN
fnp-3326	306	17	because	because	SCONJ
fnp-3326	306	18	of	of	ADP
fnp-3326	306	19	two	two	NUM
fnp-3326	306	20	reasons	reason	NOUN
fnp-3326	306	21	:	:	PUNCT
fnp-3326	306	22	1	1	X
fnp-3326	306	23	)	)	PUNCT
fnp-3326	306	24	we	we	PRON
fnp-3326	306	25	knew	know	VERB
fnp-3326	306	26	that	that	SCONJ
fnp-3326	306	27	the	the	DET
fnp-3326	306	28	model	model	NOUN
fnp-3326	306	29	as	as	ADP
fnp-3326	306	30	hemizygous	hemizygous	ADJ
fnp-3326	306	31	transgenic	transgenic	NOUN
fnp-3326	306	32	mice	mouse	NOUN
fnp-3326	306	33	exhibit	exhibit	VERB
fnp-3326	306	34	some	some	DET
fnp-3326	306	35	αsyn	αsyn	ADJ
fnp-3326	306	36	brain	brain	NOUN
fnp-3326	306	37	pathology	pathology	NOUN
fnp-3326	306	38	that	that	PRON
fnp-3326	306	39	develops	develop	VERB
fnp-3326	306	40	slowly	slowly	ADV
fnp-3326	306	41	under	under	ADP
fnp-3326	306	42	baseline	baseline	ADJ
fnp-3326	306	43	conditions	condition	NOUN
fnp-3326	306	44	.	.	PUNCT
fnp-3326	307	1	importantly	importantly	ADV
fnp-3326	307	2	,	,	PUNCT
fnp-3326	307	3	the	the	DET
fnp-3326	307	4	pathology	pathology	NOUN
fnp-3326	307	5	is	be	AUX
fnp-3326	307	6	much	much	ADV
fnp-3326	307	7	less	less	ADV
fnp-3326	307	8	pronounced	pronounced	ADJ
fnp-3326	307	9	than	than	ADP
fnp-3326	307	10	in	in	ADP
fnp-3326	307	11	homozygous	homozygous	ADJ
fnp-3326	307	12	(	(	PUNCT
fnp-3326	307	13	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	307	14	mice	mouse	NOUN
fnp-3326	308	1	[	[	X
fnp-3326	308	2	57	57	NUM
fnp-3326	308	3	]	]	SYM
fnp-3326	308	4	;	;	PUNCT
fnp-3326	308	5	2	2	X
fnp-3326	308	6	)	)	PUNCT
fnp-3326	308	7	at	at	ADP
fnp-3326	308	8	the	the	DET
fnp-3326	308	9	time	time	NOUN
fnp-3326	308	10	of	of	ADP
fnp-3326	308	11	the	the	DET
fnp-3326	308	12	experiment	experiment	NOUN
fnp-3326	308	13	,	,	PUNCT
fnp-3326	308	14	it	it	PRON
fnp-3326	308	15	was	be	AUX
fnp-3326	308	16	not	not	PART
fnp-3326	308	17	clear	clear	ADJ
fnp-3326	308	18	whether	whether	SCONJ
fnp-3326	308	19	wild	wild	ADJ
fnp-3326	308	20	type	type	NOUN
fnp-3326	308	21	mice	mouse	NOUN
fnp-3326	308	22	could	could	AUX
fnp-3326	308	23	develop	develop	VERB
fnp-3326	308	24	αsyn	αsyn	ADJ
fnp-3326	308	25	brain	brain	NOUN
fnp-3326	308	26	pathology	pathology	NOUN
fnp-3326	308	27	upon	upon	SCONJ
fnp-3326	308	28	dss	dss	NOUN
fnp-3326	308	29	colitis	colitis	NOUN
fnp-3326	308	30	.	.	PUNCT
fnp-3326	309	1	thus	thus	ADV
fnp-3326	309	2	,	,	PUNCT
fnp-3326	309	3	we	we	PRON
fnp-3326	309	4	chose	choose	VERB
fnp-3326	309	5	hemizygous	hemizygous	ADJ
fnp-3326	309	6	(	(	PUNCT
fnp-3326	309	7	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	309	8	transgenic	transgenic	NOUN
fnp-3326	309	9	mice	mouse	NOUN
fnp-3326	309	10	to	to	PART
fnp-3326	309	11	increase	increase	VERB
fnp-3326	309	12	the	the	DET
fnp-3326	309	13	chances	chance	NOUN
fnp-3326	309	14	for	for	ADP
fnp-3326	309	15	a	a	DET
fnp-3326	309	16	successful	successful	ADJ
fnp-3326	309	17	outcome	outcome	NOUN
fnp-3326	309	18	and	and	CCONJ
fnp-3326	309	19	potentially	potentially	ADV
fnp-3326	309	20	to	to	PART
fnp-3326	309	21	aggravate	aggravate	VERB
fnp-3326	309	22	the	the	DET
fnp-3326	309	23	brain	brain	NOUN
fnp-3326	309	24	pathology	pathology	NOUN
fnp-3326	309	25	from	from	ADP
fnp-3326	309	26	mild	mild	ADJ
fnp-3326	309	27	to	to	ADP
fnp-3326	309	28	strong	strong	ADJ
fnp-3326	309	29	.	.	PUNCT
fnp-3326	310	1	after	after	ADP
fnp-3326	310	2	exposing	expose	VERB
fnp-3326	310	3	the	the	DET
fnp-3326	310	4	mice	mouse	NOUN
fnp-3326	310	5	either	either	CCONJ
fnp-3326	310	6	to	to	ADP
fnp-3326	310	7	normal	normal	ADJ
fnp-3326	310	8	drinking	drinking	NOUN
fnp-3326	310	9	water	water	NOUN
fnp-3326	310	10	or	or	CCONJ
fnp-3326	310	11	a	a	DET
fnp-3326	310	12	chronic	chronic	NOUN
fnp-3326	310	13	increasing	increase	VERB
fnp-3326	310	14	dose	dose	NOUN
fnp-3326	310	15	dss	dss	NOUN
fnp-3326	310	16	paradigm	paradigm	NOUN
fnp-3326	310	17	,	,	PUNCT
fnp-3326	310	18	we	we	PRON
fnp-3326	310	19	aged	age	VERB
fnp-3326	310	20	them	they	PRON
fnp-3326	310	21	in	in	ADP
fnp-3326	310	22	two	two	NUM
fnp-3326	310	23	cohorts	cohort	NOUN
fnp-3326	310	24	on	on	ADP
fnp-3326	310	25	normal	normal	ADJ
fnp-3326	310	26	water	water	NOUN
fnp-3326	310	27	and	and	CCONJ
fnp-3326	310	28	housing	housing	NOUN
fnp-3326	310	29	conditions	condition	NOUN
fnp-3326	310	30	to	to	PART
fnp-3326	310	31	either	either	CCONJ
fnp-3326	310	32	up	up	ADP
fnp-3326	310	33	to	to	ADP
fnp-3326	310	34	the	the	DET
fnp-3326	310	35	age	age	NOUN
fnp-3326	310	36	of	of	ADP
fnp-3326	310	37	9	9	NUM
fnp-3326	310	38	months	month	NOUN
fnp-3326	310	39	or	or	CCONJ
fnp-3326	310	40	21	21	NUM
fnp-3326	310	41	months	month	NOUN
fnp-3326	310	42	.	.	PUNCT
fnp-3326	311	1	at	at	ADP
fnp-3326	311	2	these	these	DET
fnp-3326	311	3	two	two	NUM
fnp-3326	311	4	timepoints	timepoint	NOUN
fnp-3326	311	5	we	we	PRON
fnp-3326	311	6	analyzed	analyze	VERB
fnp-3326	311	7	various	various	ADJ
fnp-3326	311	8	brain	brain	NOUN
fnp-3326	311	9	regions	region	NOUN
fnp-3326	311	10	for	for	ADP
fnp-3326	311	11	αsyn	αsyn	ADJ
fnp-3326	311	12	inclusions	inclusion	NOUN
fnp-3326	311	13	that	that	PRON
fnp-3326	311	14	are	be	AUX
fnp-3326	311	15	generally	generally	ADV
fnp-3326	311	16	considered	consider	VERB
fnp-3326	311	17	pathological	pathological	ADJ
fnp-3326	311	18	by	by	ADP
fnp-3326	311	19	being	be	AUX
fnp-3326	311	20	proteinase	proteinase	ADJ
fnp-3326	311	21	k	k	PROPN
fnp-3326	311	22	(	(	PUNCT
fnp-3326	311	23	pk)-resistant	pk)-resistant	NOUN
fnp-3326	311	24	and	and	CCONJ
fnp-3326	311	25	immunopositive	immunopositive	ADJ
fnp-3326	311	26	for	for	ADP
fnp-3326	311	27	pser129	pser129	PROPN
fnp-3326	311	28	-	-	PUNCT
fnp-3326	311	29	αsyn	αsyn	NOUN
fnp-3326	311	30	.	.	PUNCT
fnp-3326	312	1	when	when	SCONJ
fnp-3326	312	2	we	we	PRON
fnp-3326	312	3	examined	examine	VERB
fnp-3326	312	4	the	the	DET
fnp-3326	312	5	9	9	NUM
fnp-3326	312	6	-	-	PUNCT
fnp-3326	312	7	month	month	NOUN
fnp-3326	312	8	-	-	PUNCT
fnp-3326	312	9	old	old	ADJ
fnp-3326	312	10	αsyn	αsyn	ADJ
fnp-3326	312	11	transgenic	transgenic	NOUN
fnp-3326	312	12	mice	mouse	NOUN
fnp-3326	312	13	,	,	PUNCT
fnp-3326	312	14	we	we	PRON
fnp-3326	312	15	found	find	VERB
fnp-3326	312	16	that	that	SCONJ
fnp-3326	312	17	both	both	DET
fnp-3326	312	18	experimental	experimental	ADJ
fnp-3326	312	19	groups	group	NOUN
fnp-3326	312	20	(	(	PUNCT
fnp-3326	312	21	i.e.	i.e.	X
fnp-3326	312	22	,	,	PUNCT
fnp-3326	312	23	those	those	PRON
fnp-3326	312	24	who	who	PRON
fnp-3326	312	25	were	be	AUX
fnp-3326	312	26	on	on	ADP
fnp-3326	312	27	dss	dss	NOUN
fnp-3326	312	28	and	and	CCONJ
fnp-3326	312	29	those	those	PRON
fnp-3326	312	30	who	who	PRON
fnp-3326	312	31	stayed	stay	VERB
fnp-3326	312	32	on	on	ADP
fnp-3326	312	33	normal	normal	ADJ
fnp-3326	312	34	water	water	NOUN
fnp-3326	312	35	throughout	throughout	ADP
fnp-3326	312	36	their	their	PRON
fnp-3326	312	37	entire	entire	ADJ
fnp-3326	312	38	life	life	NOUN
fnp-3326	312	39	and	and	CCONJ
fnp-3326	312	40	thus	thus	ADV
fnp-3326	312	41	never	never	ADV
fnp-3326	312	42	experienced	experience	VERB
fnp-3326	312	43	dss	dss	NOUN
fnp-3326	312	44	colitis	colitis	NOUN
fnp-3326	312	45	)	)	PUNCT
fnp-3326	312	46	exhibited	exhibit	VERB
fnp-3326	312	47	extremely	extremely	ADV
fnp-3326	312	48	low	low	ADJ
fnp-3326	312	49	levels	level	NOUN
fnp-3326	312	50	of	of	ADP
fnp-3326	312	51	pathological	pathological	ADJ
fnp-3326	312	52	αsyn	αsyn	NOUN
fnp-3326	312	53	aggregation	aggregation	NOUN
fnp-3326	312	54	in	in	ADP
fnp-3326	312	55	the	the	DET
fnp-3326	312	56	brain	brain	NOUN
fnp-3326	312	57	(	(	PUNCT
fnp-3326	312	58	fig	fig	NOUN
fnp-3326	312	59	.	.	NOUN
fnp-3326	312	60	5	5	NUM
fnp-3326	312	61	and	and	CCONJ
fnp-3326	312	62	suppl	suppl	ADJ
fnp-3326	312	63	.	.	PUNCT
fnp-3326	313	1	fig	fig	NOUN
fnp-3326	313	2	.	.	PUNCT
fnp-3326	314	1	5	5	NUM
fnp-3326	314	2	)	)	PUNCT
fnp-3326	314	3	.	.	PUNCT
fnp-3326	315	1	our	our	PRON
fnp-3326	315	2	observation	observation	NOUN
fnp-3326	315	3	of	of	ADP
fnp-3326	315	4	the	the	DET
fnp-3326	315	5	level	level	NOUN
fnp-3326	315	6	of	of	ADP
fnp-3326	315	7	pathological	pathological	ADJ
fnp-3326	315	8	αsyn	αsyn	ADJ
fnp-3326	315	9	aggregations	aggregation	NOUN
fnp-3326	315	10	in	in	ADP
fnp-3326	315	11	the	the	DET
fnp-3326	315	12	brain	brain	NOUN
fnp-3326	315	13	of	of	ADP
fnp-3326	315	14	these	these	DET
fnp-3326	315	15	9	9	NUM
fnp-3326	315	16	-	-	PUNCT
fnp-3326	315	17	month	month	NOUN
fnp-3326	315	18	-	-	PUNCT
fnp-3326	315	19	old	old	ADJ
fnp-3326	315	20	hemizygous	hemizygous	ADJ
fnp-3326	315	21	(	(	PUNCT
fnp-3326	315	22	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	315	23	transgenic	transgenic	NOUN
fnp-3326	315	24	mice	mouse	NOUN
fnp-3326	315	25	(	(	PUNCT
fnp-3326	315	26	fig	fig	NOUN
fnp-3326	315	27	.	.	PUNCT
fnp-3326	316	1	5a	5a	NUM
fnp-3326	316	2	)	)	PUNCT
fnp-3326	316	3	is	be	AUX
fnp-3326	316	4	indeed	indeed	ADV
fnp-3326	316	5	consistent	consistent	ADJ
fnp-3326	316	6	with	with	ADP
fnp-3326	316	7	earlier	early	ADJ
fnp-3326	316	8	descriptions	description	NOUN
fnp-3326	316	9	of	of	ADP
fnp-3326	316	10	the	the	DET
fnp-3326	316	11	model	model	NOUN
fnp-3326	316	12	at	at	ADP
fnp-3326	316	13	the	the	DET
fnp-3326	316	14	age	age	NOUN
fnp-3326	316	15	of	of	ADP
fnp-3326	316	16	11	11	NUM
fnp-3326	316	17	months	month	NOUN
fnp-3326	317	1	[	[	X
fnp-3326	317	2	57	57	NUM
fnp-3326	317	3	]	]	PUNCT
fnp-3326	317	4	.	.	PUNCT
fnp-3326	318	1	the	the	DET
fnp-3326	318	2	21	21	NUM
fnp-3326	318	3	-	-	PUNCT
fnp-3326	318	4	month	month	NOUN
fnp-3326	318	5	-	-	PUNCT
fnp-3326	318	6	old	old	ADJ
fnp-3326	318	7	hemizygous	hemizygous	ADJ
fnp-3326	318	8	(	(	PUNCT
fnp-3326	318	9	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	318	10	transgenic	transgenic	NOUN
fnp-3326	318	11	mice	mouse	NOUN
fnp-3326	318	12	that	that	PRON
fnp-3326	318	13	only	only	ADV
fnp-3326	318	14	received	receive	VERB
fnp-3326	318	15	water	water	NOUN
fnp-3326	318	16	during	during	ADP
fnp-3326	318	17	their	their	PRON
fnp-3326	318	18	lifetime	lifetime	NOUN
fnp-3326	318	19	showed	show	VERB
fnp-3326	318	20	,	,	PUNCT
fnp-3326	318	21	in	in	ADP
fnp-3326	318	22	contrast	contrast	NOUN
fnp-3326	318	23	to	to	ADP
fnp-3326	318	24	the	the	DET
fnp-3326	318	25	9	9	NUM
fnp-3326	318	26	-	-	PUNCT
fnp-3326	318	27	month	month	NOUN
fnp-3326	318	28	-	-	PUNCT
fnp-3326	318	29	old	old	ADJ
fnp-3326	318	30	cohort	cohort	NOUN
fnp-3326	318	31	,	,	PUNCT
fnp-3326	318	32	more	more	ADV
fnp-3326	318	33	discernible	discernible	ADJ
fnp-3326	318	34	pk	pk	NOUN
fnp-3326	318	35	-	-	ADJ
fnp-3326	318	36	resistant	resistant	ADJ
fnp-3326	318	37	pser129	pser129	NOUN
fnp-3326	318	38	-	-	ADJ
fnp-3326	318	39	αsyn	αsyn	ADJ
fnp-3326	318	40	immunoreactive	immunoreactive	ADJ
fnp-3326	318	41	features	feature	NOUN
fnp-3326	318	42	(	(	PUNCT
fnp-3326	318	43	fig	fig	NOUN
fnp-3326	318	44	.	.	PUNCT
fnp-3326	319	1	5b	5b	NUM
fnp-3326	319	2	)	)	PUNCT
fnp-3326	320	1	and	and	CCONJ
fnp-3326	320	2	the	the	DET
fnp-3326	320	3	abundance	abundance	NOUN
fnp-3326	320	4	of	of	ADP
fnp-3326	320	5	these	these	DET
fnp-3326	320	6	features	feature	NOUN
fnp-3326	320	7	was	be	AUX
fnp-3326	320	8	consistent	consistent	ADJ
fnp-3326	320	9	with	with	ADP
fnp-3326	320	10	previous	previous	ADJ
fnp-3326	320	11	observations	observation	NOUN
fnp-3326	320	12	in	in	ADP
fnp-3326	320	13	this	this	DET
fnp-3326	320	14	transgenic	transgenic	NOUN
fnp-3326	320	15	line	line	NOUN
fnp-3326	320	16	at	at	ADP
fnp-3326	320	17	the	the	DET
fnp-3326	320	18	age	age	NOUN
fnp-3326	320	19	of	of	ADP
fnp-3326	320	20	24	24	NUM
fnp-3326	320	21	months	month	NOUN
fnp-3326	321	1	[	[	X
fnp-3326	321	2	57	57	NUM
fnp-3326	321	3	]	]	PUNCT
fnp-3326	321	4	.	.	PUNCT
fnp-3326	322	1	in	in	ADP
fnp-3326	322	2	marked	mark	VERB
fnp-3326	322	3	contrast	contrast	NOUN
fnp-3326	322	4	,	,	PUNCT
fnp-3326	322	5	the	the	DET
fnp-3326	322	6	21	21	NUM
fnp-3326	322	7	-	-	PUNCT
fnp-3326	322	8	month	month	NOUN
fnp-3326	322	9	-	-	PUNCT
fnp-3326	322	10	old	old	ADJ
fnp-3326	322	11	hemizygous	hemizygous	ADJ
fnp-3326	322	12	(	(	PUNCT
fnp-3326	322	13	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	322	14	transgenic	transgenic	NOUN
fnp-3326	322	15	mice	mouse	NOUN
fnp-3326	322	16	that	that	PRON
fnp-3326	322	17	were	be	AUX
fnp-3326	322	18	exposed	expose	VERB
fnp-3326	322	19	to	to	ADP
fnp-3326	322	20	dss	dss	NOUN
fnp-3326	322	21	at	at	ADP
fnp-3326	322	22	three	three	NUM
fnp-3326	322	23	months	month	NOUN
fnp-3326	322	24	of	of	ADP
fnp-3326	322	25	age	age	NOUN
fnp-3326	322	26	presented	present	VERB
fnp-3326	322	27	with	with	ADP
fnp-3326	322	28	pser129	pser129	ADJ
fnp-3326	322	29	-	-	ADJ
fnp-3326	322	30	positive	positive	ADJ
fnp-3326	322	31	αsyn	αsyn	ADJ
fnp-3326	322	32	pathology	pathology	NOUN
fnp-3326	322	33	throughout	throughout	ADP
fnp-3326	322	34	various	various	ADJ
fnp-3326	322	35	brain	brain	NOUN
fnp-3326	322	36	regions	region	NOUN
fnp-3326	322	37	in	in	ADP
fnp-3326	322	38	a	a	DET
fnp-3326	322	39	much	much	ADV
fnp-3326	322	40	more	more	ADV
fnp-3326	322	41	exacerbated	exacerbate	VERB
fnp-3326	322	42	fashion	fashion	NOUN
fnp-3326	322	43	than	than	ADP
fnp-3326	322	44	mice	mouse	NOUN
fnp-3326	322	45	that	that	PRON
fnp-3326	322	46	were	be	AUX
fnp-3326	322	47	aged	age	VERB
fnp-3326	322	48	up	up	ADP
fnp-3326	322	49	to	to	PART
fnp-3326	322	50	21	21	NUM
fnp-3326	322	51	months	month	NOUN
fnp-3326	322	52	without	without	ADP
fnp-3326	322	53	having	having	AUX
fnp-3326	322	54	experienced	experience	VERB
fnp-3326	322	55	dss	dss	NOUN
fnp-3326	322	56	colitis	colitis	NOUN
fnp-3326	322	57	at	at	ADP
fnp-3326	322	58	young	young	ADJ
fnp-3326	322	59	age	age	NOUN
fnp-3326	322	60	(	(	PUNCT
fnp-3326	322	61	fig	fig	NOUN
fnp-3326	322	62	.	.	PUNCT
fnp-3326	323	1	5b	5b	NUM
fnp-3326	323	2	-	-	PUNCT
fnp-3326	323	3	e	e	NOUN
fnp-3326	323	4	)	)	PUNCT
fnp-3326	323	5	.	.	PUNCT
fnp-3326	324	1	the	the	DET
fnp-3326	324	2	degree	degree	NOUN
fnp-3326	324	3	and	and	CCONJ
fnp-3326	324	4	distribution	distribution	NOUN
fnp-3326	324	5	of	of	ADP
fnp-3326	324	6	pk	pk	NOUN
fnp-3326	324	7	-	-	ADJ
fnp-3326	324	8	resistant	resistant	ADJ
fnp-3326	324	9	αsyn	αsyn	NOUN
fnp-3326	324	10	in	in	ADP
fnp-3326	324	11	the	the	DET
fnp-3326	324	12	brain	brain	NOUN
fnp-3326	324	13	was	be	AUX
fnp-3326	324	14	similar	similar	ADJ
fnp-3326	324	15	to	to	ADP
fnp-3326	324	16	what	what	PRON
fnp-3326	324	17	was	be	AUX
fnp-3326	324	18	previously	previously	ADV
fnp-3326	324	19	described	describe	VERB
fnp-3326	324	20	for	for	ADP
fnp-3326	324	21	homozygous	homozygous	ADJ
fnp-3326	324	22	(	(	PUNCT
fnp-3326	324	23	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	324	24	transgenic	transgenic	NOUN
fnp-3326	324	25	mice	mouse	NOUN
fnp-3326	324	26	at	at	ADP
fnp-3326	324	27	the	the	DET
fnp-3326	324	28	age	age	NOUN
fnp-3326	324	29	of	of	ADP
fnp-3326	324	30	8	8	NUM
fnp-3326	324	31	to	to	PART
fnp-3326	324	32	9	9	NUM
fnp-3326	324	33	months	month	NOUN
fnp-3326	325	1	[	[	X
fnp-3326	325	2	57	57	NUM
fnp-3326	325	3	]	]	PUNCT
fnp-3326	325	4	.	.	PUNCT
fnp-3326	326	1	the	the	DET
fnp-3326	326	2	significant	significant	ADJ
fnp-3326	326	3	aggravation	aggravation	NOUN
fnp-3326	326	4	of	of	ADP
fnp-3326	326	5	αsyn	αsyn	ADJ
fnp-3326	326	6	pathology	pathology	NOUN
fnp-3326	326	7	in	in	ADP
fnp-3326	326	8	the	the	DET
fnp-3326	326	9	substantia	substantia	NOUN
fnp-3326	326	10	nigra	nigra	NOUN
fnp-3326	326	11	(	(	PUNCT
fnp-3326	326	12	p	p	NOUN
fnp-3326	326	13	≤	≤	NOUN
fnp-3326	326	14	0.01	0.01	NUM
fnp-3326	326	15	in	in	ADP
fnp-3326	326	16	a	a	DET
fnp-3326	326	17	negative	negative	ADJ
fnp-3326	326	18	-	-	PUNCT
fnp-3326	326	19	binomial	binomial	ADJ
fnp-3326	326	20	mixed	mixed	ADJ
fnp-3326	326	21	-	-	PUNCT
fnp-3326	326	22	effects	effect	NOUN
fnp-3326	326	23	model	model	NOUN
fnp-3326	326	24	adjusting	adjust	VERB
fnp-3326	326	25	for	for	ADP
fnp-3326	326	26	multiple	multiple	ADJ
fnp-3326	326	27	comparisons	comparison	NOUN
fnp-3326	326	28	performed	perform	VERB
fnp-3326	326	29	over	over	ADP
fnp-3326	326	30	all	all	DET
fnp-3326	326	31	brain	brain	NOUN
fnp-3326	326	32	areas	area	NOUN
fnp-3326	326	33	)	)	PUNCT
fnp-3326	326	34	was	be	AUX
fnp-3326	326	35	accompanied	accompany	VERB
fnp-3326	326	36	by	by	ADP
fnp-3326	326	37	a	a	DET
fnp-3326	326	38	significant	significant	ADJ
fnp-3326	326	39	loss	loss	NOUN
fnp-3326	326	40	of	of	ADP
fnp-3326	326	41	tyrosine	tyrosine	NOUN
fnp-3326	326	42	hydroxylase	hydroxylase	NOUN
fnp-3326	326	43	(	(	PUNCT
fnp-3326	326	44	th	th	NOUN
fnp-3326	326	45	)	)	PUNCT
fnp-3326	326	46	and	and	CCONJ
fnp-3326	326	47	nissl	nissl	ADJ
fnp-3326	326	48	-	-	PUNCT
fnp-3326	326	49	positive	positive	ADJ
fnp-3326	326	50	cells	cell	NOUN
fnp-3326	326	51	at	at	ADP
fnp-3326	326	52	21	21	NUM
fnp-3326	326	53	months	month	NOUN
fnp-3326	326	54	of	of	ADP
fnp-3326	326	55	age	age	NOUN
fnp-3326	326	56	(	(	PUNCT
fnp-3326	326	57	p	p	NOUN
fnp-3326	326	58	≤	≤	NOUN
fnp-3326	326	59	0.05	0.05	NUM
fnp-3326	326	60	,	,	PUNCT
fnp-3326	326	61	student	student	NOUN
fnp-3326	326	62	’s	’s	PART
fnp-3326	326	63	t	t	PROPN
fnp-3326	326	64	-	-	PUNCT
fnp-3326	326	65	test	test	NOUN
fnp-3326	326	66	;	;	PUNCT
fnp-3326	326	67	fig	fig	NOUN
fnp-3326	326	68	.	.	PUNCT
fnp-3326	327	1	6	6	NUM
fnp-3326	327	2	)	)	PUNCT
fnp-3326	327	3	.	.	PUNCT
fnp-3326	328	1	together	together	ADV
fnp-3326	328	2	,	,	PUNCT
fnp-3326	328	3	we	we	PRON
fnp-3326	328	4	found	find	VERB
fnp-3326	328	5	that	that	SCONJ
fnp-3326	328	6	experimental	experimental	ADJ
fnp-3326	328	7	dss	dss	NOUN
fnp-3326	328	8	colitis	colitis	NOUN
fnp-3326	328	9	at	at	ADP
fnp-3326	328	10	a	a	DET
fnp-3326	328	11	young	young	ADJ
fnp-3326	328	12	age	age	NOUN
fnp-3326	328	13	caused	cause	VERB
fnp-3326	328	14	an	an	DET
fnp-3326	328	15	age	age	NOUN
fnp-3326	328	16	-	-	PUNCT
fnp-3326	328	17	dependent	dependent	ADJ
fnp-3326	328	18	exacerbation	exacerbation	NOUN
fnp-3326	328	19	of	of	ADP
fnp-3326	328	20	pk	pk	NOUN
fnp-3326	328	21	-	-	ADJ
fnp-3326	328	22	resistant	resistant	ADJ
fnp-3326	328	23	pser129	pser129	ADJ
fnp-3326	328	24	-	-	ADJ
fnp-3326	328	25	αsyn	αsyn	ADJ
fnp-3326	328	26	pathology	pathology	NOUN
fnp-3326	328	27	and	and	CCONJ
fnp-3326	328	28	a	a	DET
fnp-3326	328	29	loss	loss	NOUN
fnp-3326	328	30	of	of	ADP
fnp-3326	328	31	nigral	nigral	ADJ
fnp-3326	328	32	dopaminergic	dopaminergic	ADJ
fnp-3326	328	33	neurons	neuron	NOUN
fnp-3326	328	34	in	in	ADP
fnp-3326	328	35	the	the	DET
fnp-3326	328	36	brains	brain	NOUN
fnp-3326	328	37	of	of	ADP
fnp-3326	328	38	(	(	PUNCT
fnp-3326	328	39	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	328	40	transgenic	transgenic	NOUN
fnp-3326	328	41	mice	mouse	NOUN
fnp-3326	328	42	.	.	PUNCT
fnp-3326	329	1	fig	fig	NOUN
fnp-3326	329	2	.	.	PUNCT
fnp-3326	330	1	5	5	NUM
fnp-3326	330	2	a	a	DET
fnp-3326	330	3	23	23	NUM
fnp-3326	330	4	-	-	PUNCT
fnp-3326	330	5	days	day	NOUN
fnp-3326	330	6	chronic	chronic	ADJ
fnp-3326	330	7	dss	dss	NOUN
fnp-3326	330	8	colitis	colitis	NOUN
fnp-3326	330	9	insult	insult	NOUN
fnp-3326	330	10	at	at	ADP
fnp-3326	330	11	young	young	ADJ
fnp-3326	330	12	age	age	NOUN
fnp-3326	330	13	causes	cause	VERB
fnp-3326	330	14	an	an	DET
fnp-3326	330	15	age	age	NOUN
fnp-3326	330	16	-	-	PUNCT
fnp-3326	330	17	dependent	dependent	ADJ
fnp-3326	330	18	accumulation	accumulation	NOUN
fnp-3326	330	19	of	of	ADP
fnp-3326	330	20	proteinase	proteinase	NOUN
fnp-3326	330	21	k	k	NOUN
fnp-3326	330	22	-	-	ADJ
fnp-3326	330	23	resistant	resistant	ADJ
fnp-3326	330	24	pser129	pser129	NOUN
fnp-3326	330	25	-	-	NOUN
fnp-3326	330	26	αsyn	αsyn	NOUN
fnp-3326	330	27	in	in	ADP
fnp-3326	330	28	various	various	ADJ
fnp-3326	330	29	brain	brain	NOUN
fnp-3326	330	30	regions	region	NOUN
fnp-3326	330	31	of	of	ADP
fnp-3326	330	32	(	(	PUNCT
fnp-3326	330	33	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	330	34	transgenic	transgenic	NOUN
fnp-3326	330	35	mice	mouse	NOUN
fnp-3326	330	36	.	.	PUNCT
fnp-3326	331	1	a	a	DET
fnp-3326	331	2	23	23	NUM
fnp-3326	331	3	-	-	PUNCT
fnp-3326	331	4	days	day	NOUN
fnp-3326	331	5	chronic	chronic	ADJ
fnp-3326	331	6	increasing	increase	VERB
fnp-3326	331	7	dose	dose	NOUN
fnp-3326	331	8	dss	dss	NOUN
fnp-3326	331	9	paradigm	paradigm	NOUN
fnp-3326	331	10	was	be	AUX
fnp-3326	331	11	performed	perform	VERB
fnp-3326	331	12	with	with	ADP
fnp-3326	331	13	3	3	NUM
fnp-3326	331	14	-	-	PUNCT
fnp-3326	331	15	month	month	NOUN
fnp-3326	331	16	-	-	PUNCT
fnp-3326	331	17	old	old	ADJ
fnp-3326	331	18	(	(	PUNCT
fnp-3326	331	19	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	331	20	transgenic	transgenic	NOUN
fnp-3326	331	21	mice	mouse	NOUN
fnp-3326	331	22	.	.	PUNCT
fnp-3326	332	1	after	after	ADP
fnp-3326	332	2	recovering	recover	VERB
fnp-3326	332	3	and	and	CCONJ
fnp-3326	332	4	further	further	ADJ
fnp-3326	332	5	aging	aging	NOUN
fnp-3326	332	6	,	,	PUNCT
fnp-3326	332	7	various	various	ADJ
fnp-3326	332	8	brain	brain	NOUN
fnp-3326	332	9	regions	region	NOUN
fnp-3326	332	10	were	be	AUX
fnp-3326	332	11	analyzed	analyze	VERB
fnp-3326	332	12	for	for	ADP
fnp-3326	332	13	proteinase	proteinase	PROPN
fnp-3326	332	14	k	k	PROPN
fnp-3326	332	15	(	(	PUNCT
fnp-3326	332	16	pk)-resistant	pk)-resistant	ADJ
fnp-3326	332	17	pser129	pser129	PROPN
fnp-3326	332	18	-	-	PUNCT
fnp-3326	332	19	αsyn	αsyn	NOUN
fnp-3326	332	20	immunoreactivity	immunoreactivity	NOUN
fnp-3326	332	21	in	in	ADP
fnp-3326	332	22	9	9	NUM
fnp-3326	332	23	-	-	PUNCT
fnp-3326	332	24	month	month	NOUN
fnp-3326	332	25	(	(	PUNCT
fnp-3326	332	26	a	a	NOUN
fnp-3326	332	27	)	)	PUNCT
fnp-3326	332	28	and	and	CCONJ
fnp-3326	332	29	21	21	NUM
fnp-3326	332	30	-	-	PUNCT
fnp-3326	332	31	month	month	NOUN
fnp-3326	332	32	-	-	PUNCT
fnp-3326	332	33	old	old	ADJ
fnp-3326	332	34	(	(	PUNCT
fnp-3326	332	35	b	b	NOUN
fnp-3326	332	36	)	)	PUNCT
fnp-3326	332	37	mice	mouse	NOUN
fnp-3326	332	38	,	,	PUNCT
fnp-3326	332	39	respectively	respectively	ADV
fnp-3326	332	40	.	.	PUNCT
fnp-3326	333	1	the	the	DET
fnp-3326	333	2	dark	dark	ADJ
fnp-3326	333	3	brown	brown	PROPN
fnp-3326	333	4	features	feature	NOUN
fnp-3326	333	5	in	in	ADP
fnp-3326	333	6	(	(	PUNCT
fnp-3326	333	7	a	a	NOUN
fnp-3326	333	8	)	)	PUNCT
fnp-3326	333	9	(	(	PUNCT
fnp-3326	333	10	barely	barely	ADV
fnp-3326	333	11	any	any	PRON
fnp-3326	333	12	visible	visible	ADJ
fnp-3326	333	13	in	in	ADP
fnp-3326	333	14	both	both	CCONJ
fnp-3326	333	15	the	the	DET
fnp-3326	333	16	water	water	NOUN
fnp-3326	333	17	and	and	CCONJ
fnp-3326	333	18	the	the	DET
fnp-3326	333	19	dss	dss	NOUN
fnp-3326	333	20	group	group	NOUN
fnp-3326	333	21	)	)	PUNCT
fnp-3326	333	22	and	and	CCONJ
fnp-3326	333	23	(	(	PUNCT
fnp-3326	333	24	b	b	NOUN
fnp-3326	333	25	)	)	PUNCT
fnp-3326	333	26	(	(	PUNCT
fnp-3326	333	27	strongly	strongly	ADV
fnp-3326	333	28	visible	visible	ADJ
fnp-3326	333	29	with	with	ADP
fnp-3326	333	30	typical	typical	ADJ
fnp-3326	333	31	neuritic	neuritic	ADJ
fnp-3326	333	32	and	and	CCONJ
fnp-3326	333	33	punctated	punctate	VERB
fnp-3326	333	34	inclusion	inclusion	NOUN
fnp-3326	333	35	-	-	PUNCT
fnp-3326	333	36	type	type	NOUN
fnp-3326	333	37	morphology	morphology	NOUN
fnp-3326	333	38	)	)	PUNCT
fnp-3326	333	39	indicate	indicate	VERB
fnp-3326	333	40	pk	pk	NOUN
fnp-3326	333	41	-	-	ADJ
fnp-3326	333	42	resistant	resistant	ADJ
fnp-3326	333	43	inclusions	inclusion	NOUN
fnp-3326	333	44	with	with	ADP
fnp-3326	333	45	pser129	pser129	ADJ
fnp-3326	333	46	-	-	PUNCT
fnp-3326	333	47	αsyn	αsyn	NOUN
fnp-3326	333	48	immunoreactivity	immunoreactivity	NOUN
fnp-3326	333	49	.	.	PUNCT
fnp-3326	334	1	densitometric	densitometric	ADJ
fnp-3326	334	2	quantification	quantification	NOUN
fnp-3326	334	3	of	of	ADP
fnp-3326	334	4	pser129	pser129	PROPN
fnp-3326	334	5	-	-	PUNCT
fnp-3326	334	6	αsyn	αsyn	ADJ
fnp-3326	334	7	immunoreactivity	immunoreactivity	NOUN
fnp-3326	334	8	in	in	ADP
fnp-3326	334	9	different	different	ADJ
fnp-3326	334	10	brain	brain	NOUN
fnp-3326	334	11	regions	region	NOUN
fnp-3326	334	12	of	of	ADP
fnp-3326	334	13	21	21	NUM
fnp-3326	334	14	-	-	PUNCT
fnp-3326	334	15	month	month	NOUN
fnp-3326	334	16	-	-	PUNCT
fnp-3326	334	17	old	old	ADJ
fnp-3326	334	18	mice	mouse	NOUN
fnp-3326	334	19	(	(	PUNCT
fnp-3326	334	20	c	c	X
fnp-3326	334	21	,	,	PUNCT
fnp-3326	334	22	d	d	NOUN
fnp-3326	334	23	)	)	PUNCT
fnp-3326	334	24	(	(	PUNCT
fnp-3326	334	25	n=6	n=6	NOUN
fnp-3326	334	26	mice	mouse	NOUN
fnp-3326	334	27	per	per	ADP
fnp-3326	334	28	group	group	NOUN
fnp-3326	334	29	)	)	PUNCT
fnp-3326	334	30	.	.	PUNCT
fnp-3326	335	1	in	in	ADP
fnp-3326	335	2	order	order	NOUN
fnp-3326	335	3	to	to	PART
fnp-3326	335	4	visualize	visualize	VERB
fnp-3326	335	5	better	well	ADJ
fnp-3326	335	6	the	the	DET
fnp-3326	335	7	differences	difference	NOUN
fnp-3326	335	8	between	between	ADP
fnp-3326	335	9	the	the	DET
fnp-3326	335	10	water	water	NOUN
fnp-3326	335	11	versus	versus	ADP
fnp-3326	335	12	the	the	DET
fnp-3326	335	13	dss	dss	NOUN
fnp-3326	335	14	group	group	NOUN
fnp-3326	335	15	at	at	ADP
fnp-3326	335	16	21	21	NUM
fnp-3326	335	17	months	month	NOUN
fnp-3326	335	18	,	,	PUNCT
fnp-3326	335	19	brain	brain	NOUN
fnp-3326	335	20	regions	region	NOUN
fnp-3326	335	21	with	with	ADP
fnp-3326	335	22	large	large	ADJ
fnp-3326	335	23	increase	increase	NOUN
fnp-3326	335	24	were	be	AUX
fnp-3326	335	25	plotted	plot	VERB
fnp-3326	335	26	on	on	ADP
fnp-3326	335	27	an	an	DET
fnp-3326	335	28	y	y	NOUN
fnp-3326	335	29	-	-	PUNCT
fnp-3326	335	30	axis	axis	NOUN
fnp-3326	335	31	up	up	ADP
fnp-3326	335	32	to	to	PART
fnp-3326	335	33	250	250	NUM
fnp-3326	335	34	a.u./px2	a.u./px2	PROPN
fnp-3326	335	35	and	and	CCONJ
fnp-3326	335	36	small	small	ADJ
fnp-3326	335	37	increase	increase	NOUN
fnp-3326	335	38	on	on	ADP
fnp-3326	335	39	a	a	DET
fnp-3326	335	40	y	y	NOUN
fnp-3326	335	41	-	-	PUNCT
fnp-3326	335	42	axis	axis	NOUN
fnp-3326	335	43	up	up	ADP
fnp-3326	335	44	to	to	PART
fnp-3326	335	45	40	40	NUM
fnp-3326	335	46	a.u./px2	a.u./px2	NOUN
fnp-3326	335	47	.	.	PUNCT
fnp-3326	336	1	the	the	DET
fnp-3326	336	2	about	about	ADV
fnp-3326	336	3	<	<	X
fnp-3326	336	4	5	5	NUM
fnp-3326	336	5	to	to	PART
fnp-3326	336	6	150	150	NUM
fnp-3326	336	7	a.u./px2	a.u./px2	PROPN
fnp-3326	336	8	average	average	ADJ
fnp-3326	336	9	values	value	NOUN
fnp-3326	336	10	in	in	ADP
fnp-3326	336	11	the	the	DET
fnp-3326	336	12	dss	dss	NOUN
fnp-3326	336	13	group	group	NOUN
fnp-3326	336	14	versus	versus	ADP
fnp-3326	336	15	the	the	DET
fnp-3326	336	16	about	about	ADV
fnp-3326	336	17	0	0	NUM
fnp-3326	336	18	to	to	PART
fnp-3326	336	19	30	30	NUM
fnp-3326	336	20	a.u./px2	a.u./px2	PROPN
fnp-3326	336	21	average	average	ADJ
fnp-3326	336	22	values	value	NOUN
fnp-3326	336	23	in	in	ADP
fnp-3326	336	24	the	the	DET
fnp-3326	336	25	water	water	NOUN
fnp-3326	336	26	group	group	NOUN
fnp-3326	336	27	in	in	ADP
fnp-3326	336	28	several	several	ADJ
fnp-3326	336	29	brain	brain	NOUN
fnp-3326	336	30	regions	region	NOUN
fnp-3326	336	31	confirm	confirm	VERB
fnp-3326	336	32	the	the	DET
fnp-3326	336	33	visual	visual	ADJ
fnp-3326	336	34	impression	impression	NOUN
fnp-3326	336	35	in	in	ADP
fnp-3326	336	36	panel	panel	NOUN
fnp-3326	336	37	(	(	PUNCT
fnp-3326	336	38	b	b	NOUN
fnp-3326	336	39	)	)	PUNCT
fnp-3326	336	40	.	.	PUNCT
fnp-3326	337	1	one	one	NUM
fnp-3326	337	2	21	21	NUM
fnp-3326	337	3	-	-	PUNCT
fnp-3326	337	4	month	month	NOUN
fnp-3326	337	5	-	-	PUNCT
fnp-3326	337	6	old	old	ADJ
fnp-3326	337	7	mouse	mouse	NOUN
fnp-3326	337	8	in	in	ADP
fnp-3326	337	9	the	the	DET
fnp-3326	337	10	dss	dss	NOUN
fnp-3326	337	11	group	group	NOUN
fnp-3326	337	12	was	be	AUX
fnp-3326	337	13	excluded	exclude	VERB
fnp-3326	337	14	from	from	ADP
fnp-3326	337	15	analysis	analysis	NOUN
fnp-3326	337	16	due	due	ADJ
fnp-3326	337	17	to	to	ADP
fnp-3326	337	18	presumed	presume	VERB
fnp-3326	337	19	failed	fail	VERB
fnp-3326	337	20	treatment	treatment	NOUN
fnp-3326	337	21	;	;	PUNCT
fnp-3326	337	22	it	it	PRON
fnp-3326	337	23	is	be	AUX
fnp-3326	337	24	included	include	VERB
fnp-3326	337	25	in	in	ADP
fnp-3326	337	26	the	the	DET
fnp-3326	337	27	graphs	graph	NOUN
fnp-3326	337	28	.	.	PUNCT
fnp-3326	338	1	statistical	statistical	ADJ
fnp-3326	338	2	analyses	analysis	NOUN
fnp-3326	338	3	were	be	AUX
fnp-3326	338	4	performed	perform	VERB
fnp-3326	338	5	using	use	VERB
fnp-3326	338	6	negative	negative	ADJ
fnp-3326	338	7	-	-	PUNCT
fnp-3326	338	8	binomial	binomial	ADJ
fnp-3326	338	9	mixed	mixed	ADJ
fnp-3326	338	10	-	-	PUNCT
fnp-3326	338	11	effects	effect	NOUN
fnp-3326	338	12	models	model	NOUN
fnp-3326	338	13	adjusting	adjust	VERB
fnp-3326	338	14	for	for	ADP
fnp-3326	338	15	multiple	multiple	ADJ
fnp-3326	338	16	comparisons	comparison	NOUN
fnp-3326	338	17	.	.	PUNCT
fnp-3326	339	1	e	e	X
fnp-3326	339	2	representative	representative	ADJ
fnp-3326	339	3	heatmap	heatmap	NOUN
fnp-3326	339	4	of	of	ADP
fnp-3326	339	5	the	the	DET
fnp-3326	339	6	average	average	ADJ
fnp-3326	339	7	distribution	distribution	NOUN
fnp-3326	339	8	scores	score	NOUN
fnp-3326	339	9	of	of	ADP
fnp-3326	339	10	pser129	pser129	PROPN
fnp-3326	339	11	-	-	PUNCT
fnp-3326	339	12	αsyn	αsyn	NOUN
fnp-3326	339	13	immunoreactivity	immunoreactivity	NOUN
fnp-3326	339	14	for	for	ADP
fnp-3326	339	15	each	each	DET
fnp-3326	339	16	treatment	treatment	NOUN
fnp-3326	339	17	group	group	NOUN
fnp-3326	339	18	in	in	ADP
fnp-3326	339	19	varying	vary	VERB
fnp-3326	339	20	brain	brain	NOUN
fnp-3326	339	21	regions	region	NOUN
fnp-3326	339	22	in	in	ADP
fnp-3326	339	23	all	all	DET
fnp-3326	339	24	the	the	DET
fnp-3326	339	25	9	9	NUM
fnp-3326	339	26	-	-	PUNCT
fnp-3326	339	27	month	month	NOUN
fnp-3326	339	28	(	(	PUNCT
fnp-3326	339	29	a	a	PRON
fnp-3326	339	30	and	and	CCONJ
fnp-3326	339	31	supplemental	supplemental	ADJ
fnp-3326	339	32	figure	figure	NOUN
fnp-3326	339	33	5	5	NUM
fnp-3326	339	34	)	)	PUNCT
fnp-3326	339	35	and	and	CCONJ
fnp-3326	339	36	21	21	NUM
fnp-3326	339	37	-	-	PUNCT
fnp-3326	339	38	month	month	NOUN
fnp-3326	339	39	-	-	PUNCT
fnp-3326	339	40	old	old	ADJ
fnp-3326	339	41	(	(	PUNCT
fnp-3326	339	42	b	b	NOUN
fnp-3326	339	43	)	)	PUNCT
fnp-3326	339	44	mice	mouse	NOUN
fnp-3326	339	45	was	be	AUX
fnp-3326	339	46	generated	generate	VERB
fnp-3326	339	47	in	in	ADP
fnp-3326	339	48	a	a	DET
fnp-3326	339	49	sagittal	sagittal	ADJ
fnp-3326	339	50	mouse	mouse	NOUN
fnp-3326	339	51	brain	brain	NOUN
fnp-3326	339	52	(	(	PUNCT
fnp-3326	339	53	n=10	n=10	NOUN
fnp-3326	339	54	mice	mouse	NOUN
fnp-3326	339	55	per	per	ADP
fnp-3326	339	56	group	group	NOUN
fnp-3326	339	57	)	)	PUNCT
fnp-3326	339	58	.	.	PUNCT
fnp-3326	340	1	statistical	statistical	ADJ
fnp-3326	340	2	analyses	analysis	NOUN
fnp-3326	340	3	were	be	AUX
fnp-3326	340	4	performed	perform	VERB
fnp-3326	340	5	using	use	VERB
fnp-3326	340	6	linear	linear	ADJ
fnp-3326	340	7	mixed	mixed	ADJ
fnp-3326	340	8	-	-	PUNCT
fnp-3326	340	9	effects	effect	NOUN
fnp-3326	340	10	model	model	NOUN
fnp-3326	340	11	adjusting	adjust	VERB
fnp-3326	340	12	for	for	ADP
fnp-3326	340	13	multiple	multiple	ADJ
fnp-3326	340	14	comparisons	comparison	NOUN
fnp-3326	340	15	.	.	PUNCT
fnp-3326	341	1	a.u./px2	a.u./px2	PUNCT
fnp-3326	341	2	,	,	PUNCT
fnp-3326	341	3	=	=	SYM
fnp-3326	341	4	mean	mean	VERB
fnp-3326	341	5	grey	grey	NOUN
fnp-3326	341	6	value	value	NOUN
fnp-3326	341	7	x	x	X
fnp-3326	341	8	area	area	NOUN
fnp-3326	341	9	stained	stain	VERB
fnp-3326	341	10	/	/	SYM
fnp-3326	341	11	total	total	NOUN
fnp-3326	341	12	area	area	NOUN
fnp-3326	341	13	assessed	assess	VERB
fnp-3326	341	14	.	.	PUNCT
fnp-3326	342	1	scale	scale	NOUN
fnp-3326	342	2	bars	bar	NOUN
fnp-3326	342	3	:	:	PUNCT
fnp-3326	342	4	500	500	NUM
fnp-3326	342	5	μm	μm	NOUN
fnp-3326	342	6	.	.	PUNCT
fnp-3326	343	1	discussion	discussion	NOUN
fnp-3326	343	2	currently	currently	ADV
fnp-3326	343	3	,	,	PUNCT
fnp-3326	343	4	there	there	PRON
fnp-3326	343	5	is	be	VERB
fnp-3326	343	6	no	no	DET
fnp-3326	343	7	therapy	therapy	NOUN
fnp-3326	343	8	for	for	ADP
fnp-3326	343	9	pd	pd	PROPN
fnp-3326	343	10	available	available	ADJ
fnp-3326	343	11	to	to	PART
fnp-3326	343	12	slow	slow	VERB
fnp-3326	343	13	or	or	CCONJ
fnp-3326	343	14	stop	stop	VERB
fnp-3326	343	15	disease	disease	NOUN
fnp-3326	343	16	progression	progression	NOUN
fnp-3326	343	17	and	and	CCONJ
fnp-3326	343	18	an	an	DET
fnp-3326	343	19	obstacle	obstacle	NOUN
fnp-3326	343	20	in	in	ADP
fnp-3326	343	21	the	the	DET
fnp-3326	343	22	quest	quest	NOUN
fnp-3326	343	23	to	to	PART
fnp-3326	343	24	develop	develop	VERB
fnp-3326	343	25	one	one	NUM
fnp-3326	343	26	is	be	AUX
fnp-3326	343	27	that	that	SCONJ
fnp-3326	343	28	we	we	PRON
fnp-3326	343	29	do	do	AUX
fnp-3326	343	30	not	not	PART
fnp-3326	343	31	understand	understand	VERB
fnp-3326	343	32	how	how	SCONJ
fnp-3326	343	33	the	the	DET
fnp-3326	343	34	disease	disease	NOUN
fnp-3326	343	35	develops	develop	VERB
fnp-3326	343	36	[	[	X
fnp-3326	343	37	58	58	NUM
fnp-3326	343	38	]	]	PUNCT
fnp-3326	343	39	.	.	PUNCT
fnp-3326	344	1	abnormal	abnormal	ADJ
fnp-3326	344	2	intraneuronal	intraneuronal	ADJ
fnp-3326	344	3	accumulation	accumulation	NOUN
fnp-3326	344	4	of	of	ADP
fnp-3326	344	5	αsyn	αsyn	NOUN
fnp-3326	344	6	(	(	PUNCT
fnp-3326	344	7	i.e.	i.e.	X
fnp-3326	344	8	,	,	PUNCT
fnp-3326	344	9	in	in	ADP
fnp-3326	344	10	lewy	lewy	PROPN
fnp-3326	344	11	bodies	body	NOUN
fnp-3326	344	12	and	and	CCONJ
fnp-3326	344	13	neurites	neurite	NOUN
fnp-3326	344	14	)	)	PUNCT
fnp-3326	344	15	is	be	AUX
fnp-3326	344	16	a	a	DET
fnp-3326	344	17	key	key	ADJ
fnp-3326	344	18	neuropathological	neuropathological	ADJ
fnp-3326	344	19	hallmark	hallmark	NOUN
fnp-3326	344	20	and	and	CCONJ
fnp-3326	344	21	the	the	DET
fnp-3326	344	22	distribution	distribution	NOUN
fnp-3326	344	23	of	of	ADP
fnp-3326	344	24	lewy	lewy	PROPN
fnp-3326	344	25	pathology	pathology	PROPN
fnp-3326	344	26	in	in	ADP
fnp-3326	344	27	postmortem	postmortem	NOUN
fnp-3326	344	28	brain	brain	NOUN
fnp-3326	344	29	is	be	AUX
fnp-3326	344	30	used	use	VERB
fnp-3326	344	31	for	for	ADP
fnp-3326	344	32	staging	stage	VERB
fnp-3326	344	33	in	in	ADP
fnp-3326	344	34	pd	pd	PROPN
fnp-3326	345	1	[	[	X
fnp-3326	345	2	2,59	2,59	X
fnp-3326	345	3	]	]	X
fnp-3326	345	4	.	.	PUNCT
fnp-3326	346	1	accumulation	accumulation	NOUN
fnp-3326	346	2	of	of	ADP
fnp-3326	346	3	αsyn	αsyn	PROPN
fnp-3326	346	4	has	have	AUX
fnp-3326	346	5	also	also	ADV
fnp-3326	346	6	been	be	AUX
fnp-3326	346	7	observed	observe	VERB
fnp-3326	346	8	in	in	ADP
fnp-3326	346	9	the	the	DET
fnp-3326	346	10	peripheral	peripheral	ADJ
fnp-3326	346	11	nervous	nervous	ADJ
fnp-3326	346	12	system	system	NOUN
fnp-3326	346	13	in	in	ADP
fnp-3326	346	14	pd	pd	PROPN
fnp-3326	346	15	,	,	PUNCT
fnp-3326	346	16	some	some	DET
fnp-3326	346	17	individuals	individual	NOUN
fnp-3326	346	18	at	at	ADP
fnp-3326	346	19	risk	risk	NOUN
fnp-3326	346	20	of	of	ADP
fnp-3326	346	21	developing	develop	VERB
fnp-3326	346	22	the	the	DET
fnp-3326	346	23	disease	disease	NOUN
fnp-3326	346	24	,	,	PUNCT
fnp-3326	346	25	and	and	CCONJ
fnp-3326	346	26	normal	normal	ADJ
fnp-3326	346	27	individuals	individual	NOUN
fnp-3326	346	28	[	[	X
fnp-3326	346	29	60–62	60–62	NOUN
fnp-3326	346	30	]	]	PUNCT
fnp-3326	346	31	.	.	PUNCT
fnp-3326	347	1	similar	similar	ADJ
fnp-3326	347	2	to	to	ADP
fnp-3326	347	3	this	this	DET
fnp-3326	347	4	finding	finding	NOUN
fnp-3326	347	5	in	in	ADP
fnp-3326	347	6	humans	human	NOUN
fnp-3326	347	7	,	,	PUNCT
fnp-3326	347	8	αsyn	αsyn	NOUN
fnp-3326	347	9	-	-	PUNCT
fnp-3326	347	10	immunoreactive	immunoreactive	ADJ
fnp-3326	347	11	inclusions	inclusion	NOUN
fnp-3326	347	12	and	and	CCONJ
fnp-3326	347	13	signs	sign	NOUN
fnp-3326	347	14	of	of	ADP
fnp-3326	347	15	age	age	NOUN
fnp-3326	347	16	-	-	PUNCT
fnp-3326	347	17	dependent	dependent	ADJ
fnp-3326	347	18	αsyn	αsyn	NOUN
fnp-3326	347	19	-	-	PUNCT
fnp-3326	347	20	related	relate	VERB
fnp-3326	347	21	pathological	pathological	ADJ
fnp-3326	347	22	changes	change	NOUN
fnp-3326	347	23	have	have	AUX
fnp-3326	347	24	also	also	ADV
fnp-3326	347	25	been	be	AUX
fnp-3326	347	26	detected	detect	VERB
fnp-3326	347	27	in	in	ADP
fnp-3326	347	28	the	the	DET
fnp-3326	347	29	ens	ens	NOUN
fnp-3326	347	30	of	of	ADP
fnp-3326	347	31	wild	wild	ADJ
fnp-3326	347	32	type	type	NOUN
fnp-3326	347	33	rats	rat	NOUN
fnp-3326	348	1	[	[	X
fnp-3326	348	2	63,64	63,64	X
fnp-3326	348	3	]	]	PUNCT
fnp-3326	348	4	and	and	CCONJ
fnp-3326	348	5	several	several	ADJ
fnp-3326	348	6	transgenic	transgenic	NOUN
fnp-3326	348	7	mouse	mouse	NOUN
fnp-3326	348	8	models	model	NOUN
fnp-3326	348	9	prior	prior	ADV
fnp-3326	348	10	to	to	ADP
fnp-3326	348	11	development	development	NOUN
fnp-3326	348	12	of	of	ADP
fnp-3326	348	13	brain	brain	NOUN
fnp-3326	348	14	pathology	pathology	NOUN
fnp-3326	348	15	[	[	X
fnp-3326	348	16	21,65	21,65	NOUN
fnp-3326	348	17	]	]	PUNCT
fnp-3326	348	18	.	.	PUNCT
fnp-3326	349	1	based	base	VERB
fnp-3326	349	2	on	on	ADP
fnp-3326	349	3	preclinical	preclinical	ADJ
fnp-3326	349	4	models	model	NOUN
fnp-3326	349	5	employing	employ	VERB
fnp-3326	349	6	injection	injection	NOUN
fnp-3326	349	7	of	of	ADP
fnp-3326	349	8	brain	brain	NOUN
fnp-3326	349	9	extracts	extract	NOUN
fnp-3326	349	10	or	or	CCONJ
fnp-3326	349	11	re	re	ADJ
fnp-3326	349	12	-	-	NOUN
fnp-3326	349	13	combinant	combinant	ADJ
fnp-3326	349	14	αsyn	αsyn	PROPN
fnp-3326	349	15	fibrils	fibril	NOUN
fnp-3326	349	16	to	to	ADP
fnp-3326	349	17	different	different	ADJ
fnp-3326	349	18	brain	brain	NOUN
fnp-3326	349	19	regions	region	NOUN
fnp-3326	349	20	and	and	CCONJ
fnp-3326	349	21	intestines	intestine	NOUN
fnp-3326	349	22	[	[	X
fnp-3326	349	23	15–17,19,20,46,66,67	15–17,19,20,46,66,67	NUM
fnp-3326	349	24	]	]	PUNCT
fnp-3326	349	25	together	together	ADV
fnp-3326	349	26	with	with	ADP
fnp-3326	349	27	postmortem	postmortem	NOUN
fnp-3326	349	28	brain	brain	NOUN
fnp-3326	349	29	pathology	pathology	NOUN
fnp-3326	349	30	[	[	X
fnp-3326	349	31	56,59,68	56,59,68	NUM
fnp-3326	349	32	]	]	PUNCT
fnp-3326	349	33	,	,	PUNCT
fnp-3326	349	34	it	it	PRON
fnp-3326	349	35	has	have	AUX
fnp-3326	349	36	also	also	ADV
fnp-3326	349	37	been	be	AUX
fnp-3326	349	38	suggested	suggest	VERB
fnp-3326	349	39	that	that	SCONJ
fnp-3326	349	40	αsyn	αsyn	PROPN
fnp-3326	349	41	pathology	pathology	NOUN
fnp-3326	349	42	propagates	propagate	VERB
fnp-3326	349	43	temporospatially	temporospatially	ADV
fnp-3326	349	44	from	from	ADP
fnp-3326	349	45	cell	cell	NOUN
fnp-3326	349	46	-	-	PUNCT
fnp-3326	349	47	to	to	ADP
fnp-3326	349	48	-	-	PUNCT
fnp-3326	349	49	cell	cell	NOUN
fnp-3326	349	50	in	in	ADP
fnp-3326	349	51	a	a	DET
fnp-3326	349	52	prion	prion	NOUN
fnp-3326	349	53	-	-	PUNCT
fnp-3326	349	54	like	like	ADJ
fnp-3326	349	55	manner	manner	NOUN
fnp-3326	349	56	[	[	X
fnp-3326	349	57	3,59,66,68,69	3,59,66,68,69	NUM
fnp-3326	349	58	]	]	PUNCT
fnp-3326	349	59	.	.	PUNCT
fnp-3326	350	1	however	however	ADV
fnp-3326	350	2	,	,	PUNCT
fnp-3326	350	3	the	the	DET
fnp-3326	350	4	initial	initial	ADJ
fnp-3326	350	5	factors	factor	NOUN
fnp-3326	350	6	triggering	trigger	VERB
fnp-3326	350	7	αsyn	αsyn	ADJ
fnp-3326	350	8	aggregation	aggregation	NOUN
fnp-3326	350	9	in	in	ADP
fnp-3326	350	10	the	the	DET
fnp-3326	350	11	tissue	tissue	NOUN
fnp-3326	350	12	or	or	CCONJ
fnp-3326	350	13	organ	organ	NOUN
fnp-3326	350	14	of	of	ADP
fnp-3326	350	15	origin	origin	NOUN
fnp-3326	350	16	of	of	ADP
fnp-3326	350	17	the	the	DET
fnp-3326	350	18	pathology	pathology	NOUN
fnp-3326	350	19	are	be	AUX
fnp-3326	350	20	yet	yet	ADV
fnp-3326	350	21	to	to	PART
fnp-3326	350	22	be	be	AUX
fnp-3326	350	23	established	establish	VERB
fnp-3326	350	24	[	[	X
fnp-3326	350	25	58	58	NUM
fnp-3326	350	26	]	]	PUNCT
fnp-3326	350	27	and	and	CCONJ
fnp-3326	350	28	the	the	DET
fnp-3326	350	29	involvement	involvement	NOUN
fnp-3326	350	30	of	of	ADP
fnp-3326	350	31	peripheral	peripheral	ADJ
fnp-3326	350	32	stimuli	stimulus	NOUN
fnp-3326	350	33	in	in	ADP
fnp-3326	350	34	the	the	DET
fnp-3326	350	35	aggregation	aggregation	NOUN
fnp-3326	350	36	and	and	CCONJ
fnp-3326	350	37	pathogenic	pathogenic	ADJ
fnp-3326	350	38	spread	spread	NOUN
fnp-3326	350	39	of	of	ADP
fnp-3326	350	40	αsyn	αsyn	NOUN
fnp-3326	350	41	is	be	AUX
fnp-3326	350	42	only	only	ADV
fnp-3326	350	43	beginning	begin	VERB
fnp-3326	350	44	to	to	PART
fnp-3326	350	45	unravel	unravel	VERB
fnp-3326	350	46	.	.	PUNCT
fnp-3326	351	1	in	in	ADP
fnp-3326	351	2	this	this	DET
fnp-3326	351	3	study	study	NOUN
fnp-3326	351	4	,	,	PUNCT
fnp-3326	351	5	we	we	PRON
fnp-3326	351	6	provide	provide	VERB
fnp-3326	351	7	evidence	evidence	NOUN
fnp-3326	351	8	that	that	SCONJ
fnp-3326	351	9	dss	dss	NOUN
fnp-3326	351	10	colitis	colitis	NOUN
fnp-3326	351	11	,	,	PUNCT
fnp-3326	351	12	i.e.	i.e.	X
fnp-3326	351	13	,	,	PUNCT
fnp-3326	351	14	an	an	DET
fnp-3326	351	15	experimental	experimental	ADJ
fnp-3326	351	16	ibd	ibd	NOUN
fnp-3326	351	17	-	-	PUNCT
fnp-3326	351	18	like	like	ADJ
fnp-3326	351	19	inflammation	inflammation	NOUN
fnp-3326	351	20	,	,	PUNCT
fnp-3326	351	21	triggers	trigger	VERB
fnp-3326	351	22	αsyn	αsyn	ADJ
fnp-3326	351	23	accumulation	accumulation	NOUN
fnp-3326	351	24	in	in	ADP
fnp-3326	351	25	the	the	DET
fnp-3326	351	26	ens	ens	NOUN
fnp-3326	351	27	of	of	ADP
fnp-3326	351	28	wild	wild	ADJ
fnp-3326	351	29	type	type	NOUN
fnp-3326	351	30	mice	mouse	NOUN
fnp-3326	351	31	and	and	CCONJ
fnp-3326	351	32	in	in	ADP
fnp-3326	351	33	a	a	DET
fnp-3326	351	34	human	human	ADJ
fnp-3326	351	35	αsyn	αsyn	NOUN
fnp-3326	351	36	transgenic	transgenic	NOUN
fnp-3326	351	37	mouse	mouse	NOUN
fnp-3326	351	38	model	model	NOUN
fnp-3326	351	39	of	of	ADP
fnp-3326	351	40	pd	pd	PROPN
fnp-3326	351	41	(	(	PUNCT
fnp-3326	351	42	fig	fig	NOUN
fnp-3326	351	43	.	.	PUNCT
fnp-3326	352	1	2	2	NUM
fnp-3326	352	2	)	)	PUNCT
fnp-3326	352	3	.	.	PUNCT
fnp-3326	353	1	we	we	PRON
fnp-3326	353	2	found	find	VERB
fnp-3326	353	3	aggravation	aggravation	NOUN
fnp-3326	353	4	of	of	ADP
fnp-3326	353	5	enteric	enteric	ADJ
fnp-3326	353	6	αsyn	αsyn	ADJ
fnp-3326	353	7	accumulation	accumulation	NOUN
fnp-3326	353	8	in	in	ADP
fnp-3326	353	9	αsyn	αsyn	ADJ
fnp-3326	353	10	transgenic	transgenic	NOUN
fnp-3326	353	11	mice	mouse	NOUN
fnp-3326	353	12	lacking	lack	VERB
fnp-3326	353	13	cx3cr1	cx3cr1	ADP
fnp-3326	353	14	signaling	signal	VERB
fnp-3326	353	15	and	and	CCONJ
fnp-3326	353	16	amelioration	amelioration	NOUN
fnp-3326	353	17	of	of	ADP
fnp-3326	353	18	inflammation	inflammation	NOUN
fnp-3326	353	19	and	and	CCONJ
fnp-3326	353	20	associated	associate	VERB
fnp-3326	353	21	slight	slight	ADJ
fnp-3326	353	22	reduction	reduction	NOUN
fnp-3326	353	23	of	of	ADP
fnp-3326	353	24	enteric	enteric	ADJ
fnp-3326	353	25	αsyn	αsyn	NOUN
fnp-3326	353	26	load	load	NOUN
fnp-3326	353	27	by	by	ADP
fnp-3326	353	28	systemic	systemic	ADJ
fnp-3326	353	29	il-10	il-10	PRON
fnp-3326	353	30	,	,	PUNCT
fnp-3326	353	31	demonstrating	demonstrate	VERB
fnp-3326	353	32	that	that	SCONJ
fnp-3326	353	33	genetic	genetic	ADJ
fnp-3326	353	34	and	and	CCONJ
fnp-3326	353	35	pharmacologic	pharmacologic	ADJ
fnp-3326	353	36	modulation	modulation	NOUN
fnp-3326	353	37	of	of	ADP
fnp-3326	353	38	inflammation	inflammation	NOUN
fnp-3326	353	39	can	can	AUX
fnp-3326	353	40	influence	influence	VERB
fnp-3326	353	41	the	the	DET
fnp-3326	353	42	degree	degree	NOUN
fnp-3326	353	43	of	of	ADP
fnp-3326	353	44	αsyn	αsyn	ADJ
fnp-3326	353	45	accumulation	accumulation	NOUN
fnp-3326	353	46	in	in	ADP
fnp-3326	353	47	the	the	DET
fnp-3326	353	48	ens	ens	PROPN
fnp-3326	353	49	(	(	PUNCT
fnp-3326	353	50	fig	fig	NOUN
fnp-3326	353	51	.	.	NOUN
fnp-3326	353	52	3	3	NUM
fnp-3326	353	53	and	and	CCONJ
fnp-3326	353	54	4	4	NUM
fnp-3326	353	55	)	)	PUNCT
fnp-3326	353	56	.	.	PUNCT
fnp-3326	354	1	because	because	SCONJ
fnp-3326	354	2	il-10	il-10	NUM
fnp-3326	354	3	and	and	CCONJ
fnp-3326	354	4	the	the	DET
fnp-3326	354	5	cx3cr1	cx3cr1	NOUN
fnp-3326	354	6	-	-	PUNCT
fnp-3326	354	7	cx3cl1	cx3cl1	ADJ
fnp-3326	354	8	axis	axis	NOUN
fnp-3326	354	9	are	be	AUX
fnp-3326	354	10	able	able	ADJ
fnp-3326	354	11	to	to	PART
fnp-3326	354	12	mediate	mediate	VERB
fnp-3326	354	13	this	this	DET
fnp-3326	354	14	effect	effect	NOUN
fnp-3326	354	15	,	,	PUNCT
fnp-3326	354	16	this	this	PRON
fnp-3326	354	17	suggests	suggest	VERB
fnp-3326	354	18	that	that	SCONJ
fnp-3326	354	19	monocytes	monocyte	VERB
fnp-3326	354	20	/	/	SYM
fnp-3326	354	21	macrophages	macrophage	NOUN
fnp-3326	354	22	may	may	AUX
fnp-3326	354	23	modulate	modulate	VERB
fnp-3326	354	24	the	the	DET
fnp-3326	354	25	process	process	NOUN
fnp-3326	354	26	in	in	ADP
fnp-3326	354	27	this	this	DET
fnp-3326	354	28	model	model	NOUN
fnp-3326	354	29	.	.	PUNCT
fnp-3326	355	1	we	we	PRON
fnp-3326	355	2	further	far	ADV
fnp-3326	355	3	observed	observe	VERB
fnp-3326	355	4	that	that	SCONJ
fnp-3326	355	5	the	the	DET
fnp-3326	355	6	aggravated	aggravate	VERB
fnp-3326	355	7	αsyn	αsyn	NOUN
fnp-3326	355	8	accumulation	accumulation	NOUN
fnp-3326	355	9	in	in	ADP
fnp-3326	355	10	the	the	DET
fnp-3326	355	11	ens	ens	NOUN
fnp-3326	355	12	persisted	persist	VERB
fnp-3326	355	13	even	even	ADV
fnp-3326	355	14	after	after	ADP
fnp-3326	355	15	two	two	NUM
fnp-3326	355	16	months	month	NOUN
fnp-3326	355	17	of	of	ADP
fnp-3326	355	18	recovery	recovery	NOUN
fnp-3326	355	19	from	from	ADP
fnp-3326	355	20	dss	dss	NOUN
fnp-3326	355	21	colitis	colitis	NOUN
fnp-3326	355	22	and	and	CCONJ
fnp-3326	355	23	was	be	AUX
fnp-3326	355	24	aggravated	aggravate	VERB
fnp-3326	355	25	in	in	ADP
fnp-3326	355	26	the	the	DET
fnp-3326	355	27	absence	absence	NOUN
fnp-3326	355	28	of	of	ADP
fnp-3326	355	29	cx3cr1	cx3cr1	NOUN
fnp-3326	355	30	signaling	signal	VERB
fnp-3326	355	31	.	.	PUNCT
fnp-3326	356	1	this	this	PRON
fnp-3326	356	2	indicates	indicate	VERB
fnp-3326	356	3	that	that	SCONJ
fnp-3326	356	4	the	the	DET
fnp-3326	356	5	accumulation	accumulation	NOUN
fnp-3326	356	6	is	be	AUX
fnp-3326	356	7	persistent	persistent	ADJ
fnp-3326	356	8	and	and	CCONJ
fnp-3326	356	9	this	this	PRON
fnp-3326	356	10	further	far	ADV
fnp-3326	356	11	establishes	establish	VERB
fnp-3326	356	12	that	that	SCONJ
fnp-3326	356	13	monocytes	monocyte	VERB
fnp-3326	356	14	/	/	SYM
fnp-3326	356	15	macrophages	macrophage	NOUN
fnp-3326	356	16	play	play	VERB
fnp-3326	356	17	a	a	DET
fnp-3326	356	18	critical	critical	ADJ
fnp-3326	356	19	role	role	NOUN
fnp-3326	356	20	in	in	ADP
fnp-3326	356	21	this	this	DET
fnp-3326	356	22	process	process	NOUN
fnp-3326	356	23	(	(	PUNCT
fnp-3326	357	1	suppl	suppl	PROPN
fnp-3326	357	2	.	.	PUNCT
fnp-3326	357	3	fig	fig	NOUN
fnp-3326	357	4	.	.	PUNCT
fnp-3326	358	1	4	4	NUM
fnp-3326	358	2	)	)	PUNCT
fnp-3326	358	3	.	.	PUNCT
fnp-3326	359	1	remarkably	remarkably	ADV
fnp-3326	359	2	,	,	PUNCT
fnp-3326	359	3	at	at	ADP
fnp-3326	359	4	18	18	NUM
fnp-3326	359	5	months	month	NOUN
fnp-3326	359	6	but	but	CCONJ
fnp-3326	359	7	not	not	PART
fnp-3326	359	8	6	6	NUM
fnp-3326	359	9	months	month	NOUN
fnp-3326	359	10	post	post	NOUN
fnp-3326	359	11	induction	induction	NOUN
fnp-3326	359	12	of	of	ADP
fnp-3326	359	13	dss	dss	NOUN
fnp-3326	359	14	colitis	colitis	NOUN
fnp-3326	359	15	(	(	PUNCT
fnp-3326	359	16	thus	thus	ADV
fnp-3326	359	17	,	,	PUNCT
fnp-3326	359	18	at	at	ADP
fnp-3326	359	19	age	age	NOUN
fnp-3326	359	20	21	21	NUM
fnp-3326	359	21	months	month	NOUN
fnp-3326	359	22	but	but	CCONJ
fnp-3326	359	23	not	not	PART
fnp-3326	359	24	9	9	NUM
fnp-3326	359	25	months	month	NOUN
fnp-3326	359	26	,	,	PUNCT
fnp-3326	359	27	respectively	respectively	ADV
fnp-3326	359	28	)	)	PUNCT
fnp-3326	359	29	,	,	PUNCT
fnp-3326	359	30	αsyn	αsyn	NOUN
fnp-3326	359	31	transgenic	transgenic	NOUN
fnp-3326	359	32	mice	mouse	NOUN
fnp-3326	359	33	had	have	AUX
fnp-3326	359	34	developed	develop	VERB
fnp-3326	360	1	massively	massively	ADV
fnp-3326	360	2	elevated	elevate	VERB
fnp-3326	360	3	αsyn	αsyn	ADJ
fnp-3326	360	4	brain	brain	NOUN
fnp-3326	360	5	pathology	pathology	NOUN
fnp-3326	360	6	(	(	PUNCT
fnp-3326	360	7	fig	fig	NOUN
fnp-3326	360	8	.	.	NOUN
fnp-3326	360	9	5	5	NUM
fnp-3326	360	10	and	and	CCONJ
fnp-3326	360	11	suppl	suppl	ADJ
fnp-3326	360	12	.	.	PUNCT
fnp-3326	360	13	fig	fig	NOUN
fnp-3326	360	14	.	.	PUNCT
fnp-3326	361	1	5	5	NUM
fnp-3326	361	2	)	)	PUNCT
fnp-3326	361	3	.	.	PUNCT
fnp-3326	362	1	this	this	DET
fnp-3326	362	2	elevated	elevated	ADJ
fnp-3326	362	3	pk	pk	NOUN
fnp-3326	362	4	-	-	ADJ
fnp-3326	362	5	resistant	resistant	ADJ
fnp-3326	362	6	pser129	pser129	ADJ
fnp-3326	362	7	-	-	ADJ
fnp-3326	362	8	αsyn	αsyn	ADJ
fnp-3326	362	9	pathology	pathology	NOUN
fnp-3326	362	10	in	in	ADP
fnp-3326	362	11	the	the	DET
fnp-3326	362	12	midbrain	midbrain	NOUN
fnp-3326	362	13	,	,	PUNCT
fnp-3326	362	14	including	include	VERB
fnp-3326	362	15	the	the	DET
fnp-3326	362	16	substantia	substantia	NOUN
fnp-3326	362	17	nigra	nigra	NOUN
fnp-3326	362	18	,	,	PUNCT
fnp-3326	362	19	and	and	CCONJ
fnp-3326	362	20	other	other	ADJ
fnp-3326	362	21	brain	brain	NOUN
fnp-3326	362	22	regions	region	NOUN
fnp-3326	362	23	coincided	coincide	VERB
fnp-3326	362	24	with	with	ADP
fnp-3326	362	25	an	an	DET
fnp-3326	362	26	average	average	ADJ
fnp-3326	362	27	decrease	decrease	NOUN
fnp-3326	362	28	of	of	ADP
fnp-3326	362	29	30	30	NUM
fnp-3326	362	30	-	-	SYM
fnp-3326	362	31	50	50	NUM
fnp-3326	362	32	%	%	NOUN
fnp-3326	362	33	of	of	ADP
fnp-3326	362	34	thand	thand	PROPN
fnp-3326	362	35	nissl	nissl	ADJ
fnp-3326	362	36	-	-	PUNCT
fnp-3326	362	37	positive	positive	ADJ
fnp-3326	362	38	cells	cell	NOUN
fnp-3326	362	39	in	in	ADP
fnp-3326	362	40	the	the	DET
fnp-3326	362	41	nigra	nigra	NOUN
fnp-3326	362	42	(	(	PUNCT
fnp-3326	362	43	fig	fig	NOUN
fnp-3326	362	44	.	.	PUNCT
fnp-3326	363	1	6	6	NUM
fnp-3326	363	2	)	)	PUNCT
fnp-3326	363	3	.	.	PUNCT
fnp-3326	364	1	we	we	PRON
fnp-3326	364	2	chose	choose	VERB
fnp-3326	364	3	to	to	PART
fnp-3326	364	4	perform	perform	VERB
fnp-3326	364	5	the	the	DET
fnp-3326	364	6	long	long	ADJ
fnp-3326	364	7	-	-	PUNCT
fnp-3326	364	8	term	term	NOUN
fnp-3326	364	9	experiments	experiment	NOUN
fnp-3326	364	10	in	in	ADP
fnp-3326	364	11	αsyn	αsyn	ADJ
fnp-3326	364	12	transgenic	transgenic	NOUN
fnp-3326	364	13	mice	mouse	NOUN
fnp-3326	364	14	rather	rather	ADV
fnp-3326	364	15	than	than	ADP
fnp-3326	364	16	wild	wild	ADJ
fnp-3326	364	17	type	type	NOUN
fnp-3326	364	18	mice	mouse	NOUN
fnp-3326	364	19	while	while	SCONJ
fnp-3326	364	20	being	be	AUX
fnp-3326	364	21	aware	aware	ADJ
fnp-3326	364	22	of	of	ADP
fnp-3326	364	23	the	the	DET
fnp-3326	364	24	caveats	caveat	NOUN
fnp-3326	364	25	of	of	ADP
fnp-3326	364	26	employing	employ	VERB
fnp-3326	364	27	genetic	genetic	ADJ
fnp-3326	364	28	overexpression	overexpression	NOUN
fnp-3326	364	29	models	model	NOUN
fnp-3326	364	30	,	,	PUNCT
fnp-3326	364	31	which	which	PRON
fnp-3326	364	32	use	use	VERB
fnp-3326	364	33	a	a	DET
fnp-3326	364	34	neuron	neuron	NOUN
fnp-3326	364	35	selective	selective	ADJ
fnp-3326	364	36	thy-1	thy-1	ADJ
fnp-3326	364	37	promoter	promoter	NOUN
fnp-3326	364	38	cassette	cassette	NOUN
fnp-3326	364	39	such	such	ADJ
fnp-3326	364	40	as	as	ADP
fnp-3326	364	41	these	these	PRON
fnp-3326	364	42	(	(	PUNCT
fnp-3326	364	43	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	364	44	transgenic	transgenic	NOUN
fnp-3326	364	45	mice	mouse	NOUN
fnp-3326	364	46	.	.	PUNCT
fnp-3326	365	1	however	however	ADV
fnp-3326	365	2	,	,	PUNCT
fnp-3326	365	3	these	these	DET
fnp-3326	365	4	particular	particular	ADJ
fnp-3326	365	5	αsyn	αsyn	ADJ
fnp-3326	365	6	transgenic	transgenic	NOUN
fnp-3326	365	7	mice	mouse	NOUN
fnp-3326	365	8	had	have	AUX
fnp-3326	365	9	previously	previously	ADV
fnp-3326	365	10	been	be	AUX
fnp-3326	365	11	shown	show	VERB
fnp-3326	365	12	to	to	PART
fnp-3326	365	13	slowly	slowly	ADV
fnp-3326	365	14	develop	develop	VERB
fnp-3326	365	15	αsyn	αsyn	ADJ
fnp-3326	365	16	pathology	pathology	NOUN
fnp-3326	365	17	in	in	ADP
fnp-3326	365	18	the	the	DET
fnp-3326	365	19	brain	brain	NOUN
fnp-3326	365	20	on	on	ADP
fnp-3326	365	21	a	a	DET
fnp-3326	365	22	homozygous	homozygous	ADJ
fnp-3326	365	23	genotype	genotype	NOUN
fnp-3326	366	1	[	[	X
fnp-3326	366	2	41,57	41,57	NOUN
fnp-3326	366	3	]	]	PUNCT
fnp-3326	366	4	making	make	VERB
fnp-3326	366	5	them	they	PRON
fnp-3326	366	6	ideal	ideal	ADJ
fnp-3326	366	7	when	when	SCONJ
fnp-3326	366	8	asking	ask	VERB
fnp-3326	366	9	the	the	DET
fnp-3326	366	10	question	question	NOUN
fnp-3326	366	11	of	of	ADP
fnp-3326	366	12	whether	whether	SCONJ
fnp-3326	366	13	transient	transient	ADJ
fnp-3326	366	14	colonic	colonic	ADJ
fnp-3326	366	15	inflammation	inflammation	NOUN
fnp-3326	366	16	can	can	AUX
fnp-3326	366	17	aggravate	aggravate	VERB
fnp-3326	366	18	brain	brain	NOUN
fnp-3326	366	19	pathology	pathology	NOUN
fnp-3326	366	20	in	in	ADP
fnp-3326	366	21	a	a	DET
fnp-3326	366	22	genetically	genetically	ADV
fnp-3326	366	23	predisposed	predispose	VERB
fnp-3326	366	24	animal	animal	NOUN
fnp-3326	366	25	such	such	ADJ
fnp-3326	366	26	as	as	ADP
fnp-3326	366	27	the	the	DET
fnp-3326	366	28	hemizygous	hemizygous	ADJ
fnp-3326	366	29	transgenic	transgenic	NOUN
fnp-3326	366	30	mice	mouse	NOUN
fnp-3326	366	31	used	use	VERB
fnp-3326	366	32	in	in	ADP
fnp-3326	366	33	this	this	DET
fnp-3326	366	34	study	study	NOUN
fnp-3326	366	35	.	.	PUNCT
fnp-3326	367	1	others	other	NOUN
fnp-3326	367	2	have	have	AUX
fnp-3326	367	3	recently	recently	ADV
fnp-3326	367	4	demonstrated	demonstrate	VERB
fnp-3326	367	5	in	in	ADP
fnp-3326	367	6	a	a	DET
fnp-3326	367	7	more	more	ADV
fnp-3326	367	8	aggressive	aggressive	ADJ
fnp-3326	367	9	αsyn	αsyn	ADJ
fnp-3326	367	10	transgenic	transgenic	NOUN
fnp-3326	367	11	mouse	mouse	NOUN
fnp-3326	367	12	model	model	NOUN
fnp-3326	367	13	that	that	SCONJ
fnp-3326	367	14	mild	mild	ADJ
fnp-3326	367	15	dss	dss	NOUN
fnp-3326	367	16	colitis	colitis	NOUN
fnp-3326	367	17	can	can	AUX
fnp-3326	367	18	accelerate	accelerate	VERB
fnp-3326	367	19	αsyn	αsyn	ADJ
fnp-3326	367	20	accumulation	accumulation	NOUN
fnp-3326	367	21	in	in	ADP
fnp-3326	367	22	the	the	DET
fnp-3326	367	23	ens	ens	NOUN
fnp-3326	367	24	and	and	CCONJ
fnp-3326	367	25	brain	brain	NOUN
fnp-3326	367	26	[	[	X
fnp-3326	367	27	38	38	NUM
fnp-3326	367	28	]	]	PUNCT
fnp-3326	367	29	.	.	PUNCT
fnp-3326	368	1	in	in	ADP
fnp-3326	368	2	future	future	ADJ
fnp-3326	368	3	long	long	ADJ
fnp-3326	368	4	-	-	PUNCT
fnp-3326	368	5	term	term	NOUN
fnp-3326	368	6	studies	study	NOUN
fnp-3326	368	7	,	,	PUNCT
fnp-3326	368	8	we	we	PRON
fnp-3326	368	9	plan	plan	VERB
fnp-3326	368	10	to	to	PART
fnp-3326	368	11	address	address	VERB
fnp-3326	368	12	whether	whether	SCONJ
fnp-3326	368	13	αsyn	αsyn	ADJ
fnp-3326	368	14	pathology	pathology	NOUN
fnp-3326	368	15	develops	develop	VERB
fnp-3326	368	16	also	also	ADV
fnp-3326	368	17	in	in	ADP
fnp-3326	368	18	the	the	DET
fnp-3326	368	19	brains	brain	NOUN
fnp-3326	368	20	of	of	ADP
fnp-3326	368	21	wild	wild	ADJ
fnp-3326	368	22	type	type	NOUN
fnp-3326	368	23	mice	mouse	NOUN
fnp-3326	368	24	if	if	SCONJ
fnp-3326	368	25	they	they	PRON
fnp-3326	368	26	sustain	sustain	VERB
fnp-3326	368	27	transient	transient	ADJ
fnp-3326	368	28	experimental	experimental	ADJ
fnp-3326	368	29	ibd	ibd	NOUN
fnp-3326	368	30	at	at	ADP
fnp-3326	368	31	a	a	DET
fnp-3326	368	32	young	young	ADJ
fnp-3326	368	33	age	age	NOUN
fnp-3326	368	34	.	.	PUNCT
fnp-3326	369	1	in	in	ADP
fnp-3326	369	2	our	our	PRON
fnp-3326	369	3	present	present	ADJ
fnp-3326	369	4	study	study	NOUN
fnp-3326	369	5	,	,	PUNCT
fnp-3326	369	6	experimental	experimental	ADJ
fnp-3326	369	7	dss	dss	NOUN
fnp-3326	369	8	colitis	colitis	NOUN
fnp-3326	369	9	in	in	ADP
fnp-3326	369	10	αsyn	αsyn	ADJ
fnp-3326	369	11	transgenic	transgenic	NOUN
fnp-3326	369	12	mice	mouse	NOUN
fnp-3326	369	13	recapitulated	recapitulate	VERB
fnp-3326	369	14	the	the	DET
fnp-3326	369	15	accumulation	accumulation	NOUN
fnp-3326	369	16	of	of	ADP
fnp-3326	369	17	enteric	enteric	ADJ
fnp-3326	369	18	αsyn	αsyn	NOUN
fnp-3326	369	19	which	which	PRON
fnp-3326	369	20	is	be	AUX
fnp-3326	369	21	proposed	propose	VERB
fnp-3326	369	22	to	to	PART
fnp-3326	369	23	occur	occur	VERB
fnp-3326	369	24	in	in	ADP
fnp-3326	369	25	humans	human	NOUN
fnp-3326	369	26	several	several	ADJ
fnp-3326	369	27	years	year	NOUN
fnp-3326	369	28	before	before	ADP
fnp-3326	369	29	pd	pd	PROPN
fnp-3326	369	30	diagnosis	diagnosis	NOUN
fnp-3326	369	31	[	[	X
fnp-3326	369	32	39	39	NUM
fnp-3326	369	33	]	]	PUNCT
fnp-3326	369	34	.	.	PUNCT
fnp-3326	370	1	additionally	additionally	ADV
fnp-3326	370	2	,	,	PUNCT
fnp-3326	370	3	the	the	DET
fnp-3326	370	4	subsequent	subsequent	ADJ
fnp-3326	370	5	age	age	NOUN
fnp-3326	370	6	-	-	PUNCT
fnp-3326	370	7	related	relate	VERB
fnp-3326	370	8	development	development	NOUN
fnp-3326	370	9	of	of	ADP
fnp-3326	370	10	αsyn	αsyn	ADJ
fnp-3326	370	11	pathology	pathology	NOUN
fnp-3326	370	12	in	in	ADP
fnp-3326	370	13	the	the	DET
fnp-3326	370	14	brain	brain	NOUN
fnp-3326	370	15	of	of	ADP
fnp-3326	370	16	αsyn	αsyn	ADJ
fnp-3326	370	17	transgenic	transgenic	NOUN
fnp-3326	370	18	mice	mouse	NOUN
fnp-3326	370	19	together	together	ADV
fnp-3326	370	20	with	with	ADP
fnp-3326	370	21	the	the	DET
fnp-3326	370	22	loss	loss	NOUN
fnp-3326	370	23	of	of	ADP
fnp-3326	370	24	nigral	nigral	ADJ
fnp-3326	370	25	dopaminergic	dopaminergic	ADJ
fnp-3326	370	26	neurons	neuron	NOUN
fnp-3326	370	27	mimicked	mimic	VERB
fnp-3326	370	28	a	a	DET
fnp-3326	370	29	progression	progression	NOUN
fnp-3326	370	30	of	of	ADP
fnp-3326	370	31	the	the	DET
fnp-3326	370	32	disease	disease	NOUN
fnp-3326	370	33	similar	similar	ADJ
fnp-3326	370	34	to	to	ADP
fnp-3326	370	35	what	what	PRON
fnp-3326	370	36	is	be	AUX
fnp-3326	370	37	considered	consider	VERB
fnp-3326	370	38	to	to	PART
fnp-3326	370	39	occur	occur	VERB
fnp-3326	370	40	in	in	ADP
fnp-3326	370	41	pd	pd	PROPN
fnp-3326	370	42	.	.	PROPN
fnp-3326	370	43	fig	fig	PROPN
fnp-3326	370	44	.	.	PUNCT
fnp-3326	371	1	6	6	NUM
fnp-3326	371	2	a	a	DET
fnp-3326	371	3	23	23	NUM
fnp-3326	371	4	-	-	PUNCT
fnp-3326	371	5	days	day	NOUN
fnp-3326	371	6	chronic	chronic	ADJ
fnp-3326	371	7	dss	dss	NOUN
fnp-3326	371	8	colitis	colitis	NOUN
fnp-3326	371	9	insult	insult	NOUN
fnp-3326	371	10	at	at	ADP
fnp-3326	371	11	young	young	ADJ
fnp-3326	371	12	age	age	NOUN
fnp-3326	371	13	results	result	NOUN
fnp-3326	371	14	in	in	ADP
fnp-3326	371	15	loss	loss	NOUN
fnp-3326	371	16	of	of	ADP
fnp-3326	371	17	tyrosine	tyrosine	NOUN
fnp-3326	371	18	hydroxylaseand	hydroxylaseand	PROPN
fnp-3326	371	19	nissl	nissl	ADJ
fnp-3326	371	20	-	-	PUNCT
fnp-3326	371	21	positive	positive	ADJ
fnp-3326	371	22	cells	cell	NOUN
fnp-3326	371	23	in	in	ADP
fnp-3326	371	24	the	the	DET
fnp-3326	371	25	substantia	substantia	NOUN
fnp-3326	371	26	nigra	nigra	NOUN
fnp-3326	371	27	of	of	ADP
fnp-3326	371	28	(	(	PUNCT
fnp-3326	371	29	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	371	30	transgenic	transgenic	NOUN
fnp-3326	371	31	mice	mouse	NOUN
fnp-3326	371	32	at	at	ADP
fnp-3326	371	33	21	21	NUM
fnp-3326	371	34	months	month	NOUN
fnp-3326	371	35	of	of	ADP
fnp-3326	371	36	age	age	NOUN
fnp-3326	371	37	.	.	PUNCT
fnp-3326	372	1	(	(	PUNCT
fnp-3326	372	2	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	372	3	transgenic	transgenic	NOUN
fnp-3326	372	4	mice	mouse	NOUN
fnp-3326	372	5	were	be	AUX
fnp-3326	372	6	exposed	expose	VERB
fnp-3326	372	7	to	to	ADP
fnp-3326	372	8	a	a	DET
fnp-3326	372	9	23	23	NUM
fnp-3326	372	10	-	-	PUNCT
fnp-3326	372	11	days	day	NOUN
fnp-3326	372	12	chronic	chronic	ADJ
fnp-3326	372	13	increasing	increase	VERB
fnp-3326	372	14	dose	dose	NOUN
fnp-3326	372	15	dss	dss	NOUN
fnp-3326	372	16	paradigm	paradigm	NOUN
fnp-3326	372	17	at	at	ADP
fnp-3326	372	18	the	the	DET
fnp-3326	372	19	age	age	NOUN
fnp-3326	372	20	of	of	ADP
fnp-3326	372	21	3	3	NUM
fnp-3326	372	22	months	month	NOUN
fnp-3326	372	23	followed	follow	VERB
fnp-3326	372	24	by	by	ADP
fnp-3326	372	25	aging	age	VERB
fnp-3326	372	26	on	on	ADP
fnp-3326	372	27	normal	normal	ADJ
fnp-3326	372	28	drinking	drinking	NOUN
fnp-3326	372	29	water	water	NOUN
fnp-3326	372	30	up	up	ADP
fnp-3326	372	31	to	to	ADP
fnp-3326	372	32	the	the	DET
fnp-3326	372	33	age	age	NOUN
fnp-3326	372	34	to	to	ADP
fnp-3326	372	35	21	21	NUM
fnp-3326	372	36	months	month	NOUN
fnp-3326	372	37	.	.	PUNCT
fnp-3326	373	1	these	these	DET
fnp-3326	373	2	mice	mouse	NOUN
fnp-3326	373	3	showed	show	VERB
fnp-3326	373	4	a	a	DET
fnp-3326	373	5	significant	significant	ADJ
fnp-3326	373	6	loss	loss	NOUN
fnp-3326	373	7	of	of	ADP
fnp-3326	373	8	mean	mean	ADJ
fnp-3326	373	9	count	count	NOUN
fnp-3326	373	10	of	of	ADP
fnp-3326	373	11	nissl	nissl	ADJ
fnp-3326	373	12	-	-	PUNCT
fnp-3326	373	13	positive	positive	ADJ
fnp-3326	373	14	cells	cell	NOUN
fnp-3326	373	15	with	with	ADP
fnp-3326	373	16	tyrosine	tyrosine	NOUN
fnp-3326	373	17	hydroxylase	hydroxylase	NOUN
fnp-3326	373	18	(	(	PUNCT
fnp-3326	373	19	th	th	NOUN
fnp-3326	373	20	)	)	PUNCT
fnp-3326	373	21	immunoreactivity	immunoreactivity	NOUN
fnp-3326	373	22	and	and	CCONJ
fnp-3326	373	23	cellular	cellular	ADJ
fnp-3326	373	24	nissl	nissl	NOUN
fnp-3326	373	25	staining	stain	VERB
fnp-3326	373	26	in	in	ADP
fnp-3326	373	27	the	the	DET
fnp-3326	373	28	substantia	substantia	NOUN
fnp-3326	373	29	nigra	nigra	NOUN
fnp-3326	373	30	compared	compare	VERB
fnp-3326	373	31	to	to	ADP
fnp-3326	373	32	age	age	NOUN
fnp-3326	373	33	-	-	PUNCT
fnp-3326	373	34	matched	match	VERB
fnp-3326	373	35	littermate	littermate	NOUN
fnp-3326	373	36	mice	mouse	NOUN
fnp-3326	373	37	in	in	ADP
fnp-3326	373	38	the	the	DET
fnp-3326	373	39	group	group	NOUN
fnp-3326	373	40	that	that	PRON
fnp-3326	373	41	did	do	AUX
fnp-3326	373	42	not	not	PART
fnp-3326	373	43	experience	experience	VERB
fnp-3326	373	44	dss	dss	NOUN
fnp-3326	373	45	colitis	colitis	NOUN
fnp-3326	373	46	(	(	PUNCT
fnp-3326	373	47	water	water	NOUN
fnp-3326	373	48	)	)	PUNCT
fnp-3326	373	49	.	.	PUNCT
fnp-3326	374	1	a	a	DET
fnp-3326	374	2	representative	representative	ADJ
fnp-3326	374	3	images	image	NOUN
fnp-3326	374	4	of	of	ADP
fnp-3326	374	5	two	two	NUM
fnp-3326	374	6	levels	level	NOUN
fnp-3326	374	7	of	of	ADP
fnp-3326	374	8	the	the	DET
fnp-3326	374	9	substantia	substantia	NOUN
fnp-3326	374	10	nigra	nigra	NOUN
fnp-3326	374	11	in	in	ADP
fnp-3326	374	12	one	one	NUM
fnp-3326	374	13	mouse	mouse	NOUN
fnp-3326	374	14	per	per	ADP
fnp-3326	374	15	group	group	NOUN
fnp-3326	374	16	.	.	PUNCT
fnp-3326	375	1	b	b	ADP
fnp-3326	375	2	stereological	stereological	ADJ
fnp-3326	375	3	quantification	quantification	NOUN
fnp-3326	375	4	of	of	ADP
fnp-3326	375	5	cells	cell	NOUN
fnp-3326	375	6	positive	positive	ADJ
fnp-3326	375	7	for	for	ADP
fnp-3326	375	8	th	th	PRON
fnp-3326	375	9	or	or	CCONJ
fnp-3326	375	10	nissl	nissl	NOUN
fnp-3326	375	11	(	(	PUNCT
fnp-3326	375	12	n=7	n=7	PROPN
fnp-3326	375	13	-	-	PUNCT
fnp-3326	375	14	8	8	NUM
fnp-3326	375	15	mice	mouse	NOUN
fnp-3326	375	16	per	per	ADP
fnp-3326	375	17	group	group	NOUN
fnp-3326	375	18	)	)	PUNCT
fnp-3326	375	19	.	.	PUNCT
fnp-3326	376	1	statistical	statistical	ADJ
fnp-3326	376	2	analyses	analysis	NOUN
fnp-3326	376	3	of	of	ADP
fnp-3326	376	4	the	the	DET
fnp-3326	376	5	th	th	NUM
fnp-3326	376	6	dataset	dataset	NOUN
fnp-3326	376	7	were	be	AUX
fnp-3326	376	8	performed	perform	VERB
fnp-3326	376	9	using	use	VERB
fnp-3326	376	10	student	student	NOUN
fnp-3326	376	11	’s	’s	PART
fnp-3326	376	12	t	t	PROPN
fnp-3326	376	13	-	-	PUNCT
fnp-3326	376	14	test	test	NOUN
fnp-3326	376	15	,	,	PUNCT
fnp-3326	376	16	while	while	SCONJ
fnp-3326	376	17	welch	welch	PROPN
fnp-3326	376	18	’s	’s	PART
fnp-3326	376	19	t	t	PROPN
fnp-3326	376	20	-	-	PUNCT
fnp-3326	376	21	test	test	NOUN
fnp-3326	376	22	was	be	AUX
fnp-3326	376	23	used	use	VERB
fnp-3326	376	24	for	for	ADP
fnp-3326	376	25	the	the	DET
fnp-3326	376	26	nissl	nissl	ADJ
fnp-3326	376	27	dataset	dataset	NOUN
fnp-3326	376	28	to	to	PART
fnp-3326	376	29	adjust	adjust	VERB
fnp-3326	376	30	for	for	ADP
fnp-3326	376	31	unequal	unequal	ADJ
fnp-3326	376	32	variances	variance	NOUN
fnp-3326	376	33	.	.	PUNCT
fnp-3326	377	1	scale	scale	NOUN
fnp-3326	377	2	bar	bar	NOUN
fnp-3326	377	3	:	:	PUNCT
fnp-3326	377	4	500	500	NUM
fnp-3326	377	5	μm	μm	NOUN
fnp-3326	377	6	.	.	PUNCT
fnp-3326	378	1	we	we	PRON
fnp-3326	378	2	established	establish	VERB
fnp-3326	378	3	that	that	SCONJ
fnp-3326	378	4	a	a	DET
fnp-3326	378	5	mechanism	mechanism	NOUN
fnp-3326	378	6	by	by	ADP
fnp-3326	378	7	which	which	PRON
fnp-3326	378	8	a	a	DET
fnp-3326	378	9	specific	specific	ADJ
fnp-3326	378	10	type	type	NOUN
fnp-3326	378	11	of	of	ADP
fnp-3326	378	12	peripheral	peripheral	ADJ
fnp-3326	378	13	inflammation	inflammation	NOUN
fnp-3326	378	14	promotes	promote	VERB
fnp-3326	378	15	αsyn	αsyn	ADJ
fnp-3326	378	16	accumulation	accumulation	NOUN
fnp-3326	378	17	in	in	ADP
fnp-3326	378	18	the	the	DET
fnp-3326	378	19	colon	colon	NOUN
fnp-3326	378	20	potentially	potentially	ADV
fnp-3326	378	21	involves	involve	VERB
fnp-3326	378	22	monocytes	monocyte	NOUN
fnp-3326	378	23	and	and	CCONJ
fnp-3326	378	24	macrophages	macrophage	NOUN
fnp-3326	378	25	.	.	PUNCT
fnp-3326	379	1	both	both	DET
fnp-3326	379	2	peroral	peroral	ADJ
fnp-3326	379	3	dss	dss	NOUN
fnp-3326	379	4	and	and	CCONJ
fnp-3326	379	5	intraperitoneal	intraperitoneal	PROPN
fnp-3326	379	6	lps	lps	PROPN
fnp-3326	379	7	administration	administration	NOUN
fnp-3326	379	8	provoked	provoke	VERB
fnp-3326	379	9	strong	strong	ADJ
fnp-3326	379	10	local	local	ADJ
fnp-3326	379	11	immune	immune	ADJ
fnp-3326	379	12	reactions	reaction	NOUN
fnp-3326	379	13	resulting	result	VERB
fnp-3326	379	14	in	in	ADP
fnp-3326	379	15	leukocyte	leukocyte	ADJ
fnp-3326	379	16	infiltration	infiltration	NOUN
fnp-3326	379	17	into	into	ADP
fnp-3326	379	18	the	the	DET
fnp-3326	379	19	submucosa	submucosa	NOUN
fnp-3326	379	20	of	of	ADP
fnp-3326	379	21	the	the	DET
fnp-3326	379	22	colon	colon	NOUN
fnp-3326	379	23	.	.	PUNCT
fnp-3326	380	1	the	the	DET
fnp-3326	380	2	inflamed	inflame	VERB
fnp-3326	380	3	region	region	NOUN
fnp-3326	380	4	of	of	ADP
fnp-3326	380	5	the	the	DET
fnp-3326	380	6	colon	colon	NOUN
fnp-3326	380	7	contains	contain	VERB
fnp-3326	380	8	the	the	DET
fnp-3326	380	9	submucosal	submucosal	NOUN
fnp-3326	380	10	plexus	plexus	NOUN
fnp-3326	380	11	and	and	CCONJ
fnp-3326	380	12	is	be	AUX
fnp-3326	380	13	anatomically	anatomically	ADV
fnp-3326	380	14	separated	separate	VERB
fnp-3326	380	15	from	from	ADP
fnp-3326	380	16	the	the	DET
fnp-3326	380	17	myenteric	myenteric	ADJ
fnp-3326	380	18	plexus	plexus	NOUN
fnp-3326	380	19	by	by	ADP
fnp-3326	380	20	a	a	DET
fnp-3326	380	21	thick	thick	ADJ
fnp-3326	380	22	circular	circular	ADJ
fnp-3326	380	23	muscle	muscle	NOUN
fnp-3326	380	24	(	(	PUNCT
fnp-3326	380	25	fig	fig	NOUN
fnp-3326	380	26	.	.	PUNCT
fnp-3326	381	1	1	1	NUM
fnp-3326	381	2	)	)	PUNCT
fnp-3326	381	3	.	.	PUNCT
fnp-3326	382	1	this	this	DET
fnp-3326	382	2	discrete	discrete	ADJ
fnp-3326	382	3	localization	localization	NOUN
fnp-3326	382	4	of	of	ADP
fnp-3326	382	5	inflammation	inflammation	NOUN
fnp-3326	382	6	to	to	ADP
fnp-3326	382	7	the	the	DET
fnp-3326	382	8	submucosa	submucosa	NOUN
fnp-3326	382	9	might	might	AUX
fnp-3326	382	10	explain	explain	VERB
fnp-3326	382	11	why	why	SCONJ
fnp-3326	382	12	αsyn	αsyn	NOUN
fnp-3326	382	13	only	only	ADV
fnp-3326	382	14	accumulated	accumulate	VERB
fnp-3326	382	15	in	in	ADP
fnp-3326	382	16	the	the	DET
fnp-3326	382	17	nerves	nerve	NOUN
fnp-3326	382	18	of	of	ADP
fnp-3326	382	19	the	the	DET
fnp-3326	382	20	submucosal	submucosal	NOUN
fnp-3326	382	21	plexus	plexus	NOUN
fnp-3326	382	22	and	and	CCONJ
fnp-3326	382	23	not	not	PART
fnp-3326	382	24	in	in	ADP
fnp-3326	382	25	the	the	DET
fnp-3326	382	26	myenteric	myenteric	ADJ
fnp-3326	382	27	plexus	plexus	NOUN
fnp-3326	382	28	of	of	ADP
fnp-3326	382	29	our	our	PRON
fnp-3326	382	30	mice	mouse	NOUN
fnp-3326	382	31	that	that	PRON
fnp-3326	382	32	received	receive	VERB
fnp-3326	382	33	dss	dss	NOUN
fnp-3326	382	34	in	in	ADP
fnp-3326	382	35	both	both	CCONJ
fnp-3326	382	36	a	a	DET
fnp-3326	382	37	strong	strong	ADJ
fnp-3326	382	38	acute	acute	NOUN
fnp-3326	382	39	and	and	CCONJ
fnp-3326	382	40	the	the	DET
fnp-3326	382	41	two	two	NUM
fnp-3326	382	42	chronic	chronic	NOUN
fnp-3326	382	43	paradigms	paradigm	VERB
fnp-3326	382	44	.	.	PUNCT
fnp-3326	383	1	the	the	DET
fnp-3326	383	2	mechanism	mechanism	NOUN
fnp-3326	383	3	underlying	underlie	VERB
fnp-3326	383	4	how	how	SCONJ
fnp-3326	383	5	intraperitoneally	intraperitoneally	ADV
fnp-3326	383	6	administered	administer	VERB
fnp-3326	383	7	lps	lps	PROPN
fnp-3326	383	8	leads	lead	VERB
fnp-3326	383	9	to	to	ADP
fnp-3326	383	10	submucosal	submucosal	NOUN
fnp-3326	383	11	leukocyte	leukocyte	NOUN
fnp-3326	383	12	infiltration	infiltration	NOUN
fnp-3326	383	13	likely	likely	ADV
fnp-3326	383	14	involves	involve	VERB
fnp-3326	383	15	the	the	DET
fnp-3326	383	16	monocyte	monocyte	NOUN
fnp-3326	383	17	attractant	attractant	ADJ
fnp-3326	383	18	chemokine	chemokine	ADJ
fnp-3326	383	19	ccl2	ccl2	NOUN
fnp-3326	383	20	(	(	PUNCT
fnp-3326	383	21	fig	fig	NOUN
fnp-3326	383	22	.	.	PUNCT
fnp-3326	384	1	3	3	NUM
fnp-3326	384	2	)	)	PUNCT
fnp-3326	384	3	,	,	PUNCT
fnp-3326	384	4	but	but	CCONJ
fnp-3326	384	5	the	the	DET
fnp-3326	384	6	specifics	specific	NOUN
fnp-3326	384	7	remain	remain	VERB
fnp-3326	384	8	to	to	PART
fnp-3326	384	9	be	be	AUX
fnp-3326	384	10	clarified	clarify	VERB
fnp-3326	384	11	[	[	PUNCT
fnp-3326	384	12	70	70	NUM
fnp-3326	384	13	]	]	PUNCT
fnp-3326	384	14	.	.	PUNCT
fnp-3326	385	1	indeed	indeed	ADV
fnp-3326	385	2	,	,	PUNCT
fnp-3326	385	3	ccl2	ccl2	PROPN
fnp-3326	385	4	was	be	AUX
fnp-3326	385	5	also	also	ADV
fnp-3326	385	6	upregulated	upregulate	VERB
fnp-3326	385	7	in	in	ADP
fnp-3326	385	8	the	the	DET
fnp-3326	385	9	colon	colon	NOUN
fnp-3326	385	10	of	of	ADP
fnp-3326	385	11	our	our	PRON
fnp-3326	385	12	dss	dss	NOUN
fnp-3326	385	13	model	model	NOUN
fnp-3326	385	14	.	.	PUNCT
fnp-3326	386	1	however	however	ADV
fnp-3326	386	2	,	,	PUNCT
fnp-3326	386	3	in	in	ADP
fnp-3326	386	4	contrast	contrast	NOUN
fnp-3326	386	5	to	to	ADP
fnp-3326	386	6	intraperitoneal	intraperitoneal	ADJ
fnp-3326	386	7	lps	lps	PROPN
fnp-3326	386	8	,	,	PUNCT
fnp-3326	386	9	where	where	SCONJ
fnp-3326	386	10	infiltrating	infiltrating	ADJ
fnp-3326	386	11	macrophages	macrophage	NOUN
fnp-3326	386	12	were	be	AUX
fnp-3326	386	13	present	present	ADJ
fnp-3326	386	14	in	in	ADP
fnp-3326	386	15	discrete	discrete	ADJ
fnp-3326	386	16	patches	patch	NOUN
fnp-3326	386	17	in	in	ADP
fnp-3326	386	18	the	the	DET
fnp-3326	386	19	colonic	colonic	NOUN
fnp-3326	386	20	wall	wall	NOUN
fnp-3326	386	21	,	,	PUNCT
fnp-3326	386	22	dss	dss	NOUN
fnp-3326	386	23	-	-	PUNCT
fnp-3326	386	24	related	relate	VERB
fnp-3326	386	25	macrophage	macrophage	ADJ
fnp-3326	386	26	infiltration	infiltration	NOUN
fnp-3326	386	27	was	be	AUX
fnp-3326	386	28	distributed	distribute	VERB
fnp-3326	386	29	both	both	CCONJ
fnp-3326	386	30	in	in	ADP
fnp-3326	386	31	small	small	ADJ
fnp-3326	386	32	groups	group	NOUN
fnp-3326	386	33	and	and	CCONJ
fnp-3326	386	34	larger	large	ADJ
fnp-3326	386	35	randomly	randomly	ADV
fnp-3326	386	36	distributed	distribute	VERB
fnp-3326	386	37	patches	patch	NOUN
fnp-3326	386	38	of	of	ADP
fnp-3326	386	39	cells	cell	NOUN
fnp-3326	386	40	across	across	ADP
fnp-3326	386	41	the	the	DET
fnp-3326	386	42	entire	entire	ADJ
fnp-3326	386	43	colonic	colonic	NOUN
fnp-3326	386	44	submucosa	submucosa	NOUN
fnp-3326	386	45	.	.	PUNCT
fnp-3326	387	1	also	also	ADV
fnp-3326	387	2	,	,	PUNCT
fnp-3326	387	3	perorally	perorally	ADV
fnp-3326	387	4	administered	administer	VERB
fnp-3326	387	5	dss	dss	NOUN
fnp-3326	387	6	destroys	destroy	VERB
fnp-3326	387	7	the	the	DET
fnp-3326	387	8	mucosa	mucosa	NOUN
fnp-3326	387	9	of	of	ADP
fnp-3326	387	10	the	the	DET
fnp-3326	387	11	colon	colon	NOUN
fnp-3326	387	12	,	,	PUNCT
fnp-3326	387	13	similar	similar	ADJ
fnp-3326	387	14	to	to	ADP
fnp-3326	387	15	some	some	DET
fnp-3326	387	16	forms	form	NOUN
fnp-3326	387	17	of	of	ADP
fnp-3326	387	18	ulcerative	ulcerative	ADJ
fnp-3326	387	19	colitis	colitis	NOUN
fnp-3326	387	20	,	,	PUNCT
fnp-3326	387	21	resulting	result	VERB
fnp-3326	387	22	in	in	ADP
fnp-3326	387	23	the	the	DET
fnp-3326	387	24	transient	transient	ADJ
fnp-3326	387	25	disintegration	disintegration	NOUN
fnp-3326	387	26	of	of	ADP
fnp-3326	387	27	the	the	DET
fnp-3326	387	28	intestinal	intestinal	ADJ
fnp-3326	387	29	epithelial	epithelial	ADJ
fnp-3326	387	30	barrier	barrier	NOUN
fnp-3326	387	31	.	.	PUNCT
fnp-3326	388	1	in	in	ADP
fnp-3326	388	2	our	our	PRON
fnp-3326	388	3	(	(	PUNCT
fnp-3326	388	4	thy1)-h[a30p]αsyn	thy1)-h[a30p]αsyn	NOUN
fnp-3326	388	5	transgenic	transgenic	NOUN
fnp-3326	388	6	mice	mouse	NOUN
fnp-3326	388	7	,	,	PUNCT
fnp-3326	388	8	the	the	DET
fnp-3326	388	9	subsequent	subsequent	ADJ
fnp-3326	388	10	immune	immune	ADJ
fnp-3326	388	11	response	response	NOUN
fnp-3326	388	12	to	to	ADP
fnp-3326	388	13	the	the	DET
fnp-3326	388	14	infiltration	infiltration	NOUN
fnp-3326	388	15	of	of	ADP
fnp-3326	388	16	commensal	commensal	NOUN
fnp-3326	388	17	bacteria	bacteria	NOUN
fnp-3326	388	18	evoked	evoke	VERB
fnp-3326	388	19	an	an	DET
fnp-3326	388	20	elevated	elevated	ADJ
fnp-3326	388	21	expression	expression	NOUN
fnp-3326	388	22	of	of	ADP
fnp-3326	388	23	cytokines	cytokine	NOUN
fnp-3326	388	24	such	such	ADJ
fnp-3326	388	25	as	as	ADP
fnp-3326	388	26	il-1β	il-1β	PROPN
fnp-3326	388	27	and	and	CCONJ
fnp-3326	388	28	il-6	il-6	NOUN
fnp-3326	388	29	,	,	PUNCT
fnp-3326	388	30	a	a	DET
fnp-3326	388	31	phenomenon	phenomenon	NOUN
fnp-3326	388	32	also	also	ADV
fnp-3326	388	33	observed	observe	VERB
fnp-3326	388	34	in	in	ADP
fnp-3326	388	35	the	the	DET
fnp-3326	388	36	colon	colon	NOUN
fnp-3326	388	37	of	of	ADP
fnp-3326	388	38	ibd	ibd	NOUN
fnp-3326	388	39	patients	patient	NOUN
fnp-3326	388	40	[	[	X
fnp-3326	388	41	71,72	71,72	X
fnp-3326	388	42	]	]	PUNCT
fnp-3326	388	43	.	.	PUNCT
fnp-3326	389	1	this	this	DET
fnp-3326	389	2	upregulation	upregulation	NOUN
fnp-3326	389	3	was	be	AUX
fnp-3326	389	4	absent	absent	ADJ
fnp-3326	389	5	in	in	ADP
fnp-3326	389	6	the	the	DET
fnp-3326	389	7	lps	lps	PROPN
fnp-3326	389	8	paradigm	paradigm	NOUN
fnp-3326	389	9	in	in	ADP
fnp-3326	389	10	which	which	PRON
fnp-3326	389	11	the	the	DET
fnp-3326	389	12	intestinal	intestinal	ADJ
fnp-3326	389	13	mucosa	mucosa	NOUN
fnp-3326	389	14	remained	remain	VERB
fnp-3326	389	15	intact	intact	ADJ
fnp-3326	389	16	.	.	PUNCT
fnp-3326	390	1	by	by	ADP
fnp-3326	390	2	acting	act	VERB
fnp-3326	390	3	on	on	ADP
fnp-3326	390	4	tight	tight	ADJ
fnp-3326	390	5	junctions	junction	NOUN
fnp-3326	390	6	,	,	PUNCT
fnp-3326	390	7	il-1β	il-1β	PROPN
fnp-3326	390	8	and	and	CCONJ
fnp-3326	390	9	il-6	il-6	NOUN
fnp-3326	390	10	can	can	AUX
fnp-3326	390	11	increase	increase	VERB
fnp-3326	390	12	intestinal	intestinal	ADJ
fnp-3326	390	13	barrier	barrier	NOUN
fnp-3326	390	14	permeability	permeability	NOUN
fnp-3326	390	15	(	(	PUNCT
fnp-3326	390	16	gut	gut	NOUN
fnp-3326	390	17	leakiness	leakiness	NOUN
fnp-3326	390	18	)	)	PUNCT
fnp-3326	390	19	,	,	PUNCT
fnp-3326	390	20	facilitating	facilitate	VERB
fnp-3326	390	21	the	the	DET
fnp-3326	390	22	recruitment	recruitment	NOUN
fnp-3326	390	23	of	of	ADP
fnp-3326	390	24	additional	additional	ADJ
fnp-3326	390	25	immune	immune	ADJ
fnp-3326	390	26	cells	cell	NOUN
fnp-3326	390	27	to	to	ADP
fnp-3326	390	28	the	the	DET
fnp-3326	390	29	site	site	NOUN
fnp-3326	390	30	of	of	ADP
fnp-3326	390	31	the	the	DET
fnp-3326	390	32	inflammation	inflammation	NOUN
fnp-3326	390	33	,	,	PUNCT
fnp-3326	390	34	eventually	eventually	ADV
fnp-3326	390	35	culminating	culminate	VERB
fnp-3326	390	36	in	in	ADP
fnp-3326	390	37	widespread	widespread	ADJ
fnp-3326	390	38	immune	immune	ADJ
fnp-3326	390	39	activation	activation	NOUN
fnp-3326	390	40	[	[	X
fnp-3326	390	41	73,74	73,74	NOUN
fnp-3326	390	42	]	]	PUNCT
fnp-3326	390	43	.	.	PUNCT
fnp-3326	391	1	consistent	consistent	ADJ
fnp-3326	391	2	with	with	ADP
fnp-3326	391	3	the	the	DET
fnp-3326	391	4	breach	breach	NOUN
fnp-3326	391	5	of	of	ADP
fnp-3326	391	6	barrier	barrier	NOUN
fnp-3326	391	7	permeability	permeability	NOUN
fnp-3326	391	8	in	in	ADP
fnp-3326	391	9	our	our	PRON
fnp-3326	391	10	mouse	mouse	NOUN
fnp-3326	391	11	model	model	NOUN
fnp-3326	391	12	,	,	PUNCT
fnp-3326	391	13	some	some	DET
fnp-3326	391	14	pd	pd	PROPN
fnp-3326	391	15	patients	patient	NOUN
fnp-3326	391	16	exhibit	exhibit	VERB
fnp-3326	391	17	increased	increase	VERB
fnp-3326	391	18	colonic	colonic	ADJ
fnp-3326	391	19	cytokines	cytokine	NOUN
fnp-3326	391	20	such	such	ADJ
fnp-3326	391	21	as	as	ADP
fnp-3326	391	22	il-1β	il-1β	PROPN
fnp-3326	391	23	,	,	PUNCT
fnp-3326	391	24	il-6	il-6	NUM
fnp-3326	391	25	and	and	CCONJ
fnp-3326	391	26	tnf	tnf	PROPN
fnp-3326	391	27	,	,	PUNCT
fnp-3326	391	28	occurring	occur	VERB
fnp-3326	391	29	together	together	ADV
fnp-3326	391	30	with	with	ADP
fnp-3326	391	31	increased	increase	VERB
fnp-3326	391	32	intestinal	intestinal	ADJ
fnp-3326	391	33	permeability	permeability	NOUN
fnp-3326	392	1	[	[	X
fnp-3326	392	2	23,75	23,75	NUM
fnp-3326	392	3	]	]	X
fnp-3326	392	4	.	.	PUNCT
fnp-3326	393	1	in	in	ADP
fnp-3326	393	2	this	this	DET
fnp-3326	393	3	context	context	NOUN
fnp-3326	393	4	,	,	PUNCT
fnp-3326	393	5	it	it	PRON
fnp-3326	393	6	is	be	AUX
fnp-3326	393	7	also	also	ADV
fnp-3326	393	8	notable	notable	ADJ
fnp-3326	393	9	that	that	SCONJ
fnp-3326	393	10	people	people	NOUN
fnp-3326	393	11	with	with	ADP
fnp-3326	393	12	crohn	crohn	PROPN
fnp-3326	393	13	’s	’s	PART
fnp-3326	393	14	disease	disease	NOUN
fnp-3326	393	15	present	present	ADJ
fnp-3326	393	16	with	with	ADP
fnp-3326	393	17	increased	increase	VERB
fnp-3326	393	18	enteric	enteric	ADJ
fnp-3326	393	19	αsyn	αsyn	NOUN
fnp-3326	393	20	expression	expression	NOUN
fnp-3326	393	21	[	[	X
fnp-3326	393	22	55	55	NUM
fnp-3326	393	23	]	]	PUNCT
fnp-3326	393	24	and	and	CCONJ
fnp-3326	393	25	even	even	ADV
fnp-3326	393	26	more	more	ADV
fnp-3326	393	27	striking	striking	ADJ
fnp-3326	393	28	that	that	SCONJ
fnp-3326	393	29	ibd	ibd	PROPN
fnp-3326	393	30	patients	patient	NOUN
fnp-3326	393	31	on	on	ADP
fnp-3326	393	32	anti	anti	ADJ
fnp-3326	393	33	-	-	ADJ
fnp-3326	393	34	tnf	tnf	ADJ
fnp-3326	393	35	therapy	therapy	NOUN
fnp-3326	393	36	have	have	VERB
fnp-3326	393	37	a	a	DET
fnp-3326	393	38	reduced	reduced	ADJ
fnp-3326	393	39	risk	risk	NOUN
fnp-3326	393	40	of	of	ADP
fnp-3326	393	41	developing	develop	VERB
fnp-3326	393	42	pd	pd	PROPN
fnp-3326	393	43	compared	compare	VERB
fnp-3326	393	44	to	to	ADP
fnp-3326	393	45	ibd	ibd	NOUN
fnp-3326	393	46	patients	patient	NOUN
fnp-3326	393	47	not	not	PART
fnp-3326	393	48	given	give	VERB
fnp-3326	393	49	this	this	DET
fnp-3326	393	50	treatment	treatment	NOUN
fnp-3326	393	51	[	[	X
fnp-3326	393	52	35	35	NUM
fnp-3326	393	53	]	]	PUNCT
fnp-3326	393	54	.	.	PUNCT
fnp-3326	394	1	notably	notably	ADV
fnp-3326	394	2	,	,	PUNCT
fnp-3326	394	3	mucosal	mucosal	ADJ
fnp-3326	394	4	macrophages	macrophage	NOUN
fnp-3326	394	5	with	with	ADP
fnp-3326	394	6	intra	intra	ADJ
fnp-3326	394	7	-	-	ADJ
fnp-3326	394	8	lysosomal	lysosomal	ADJ
fnp-3326	394	9	αsyn	αsyn	NOUN
fnp-3326	394	10	content	content	NOUN
fnp-3326	394	11	were	be	AUX
fnp-3326	394	12	previously	previously	ADV
fnp-3326	394	13	described	describe	VERB
fnp-3326	394	14	in	in	ADP
fnp-3326	394	15	the	the	DET
fnp-3326	394	16	intact	intact	ADJ
fnp-3326	394	17	human	human	ADJ
fnp-3326	394	18	appendix	appendix	NOUN
fnp-3326	394	19	[	[	X
fnp-3326	394	20	76	76	NUM
fnp-3326	394	21	]	]	PUNCT
fnp-3326	394	22	.	.	PUNCT
fnp-3326	395	1	these	these	DET
fnp-3326	395	2	macrophages	macrophage	NOUN
fnp-3326	395	3	were	be	AUX
fnp-3326	395	4	in	in	ADP
fnp-3326	395	5	close	close	ADJ
fnp-3326	395	6	proximity	proximity	NOUN
fnp-3326	395	7	to	to	ADP
fnp-3326	395	8	the	the	DET
fnp-3326	395	9	axonal	axonal	ADJ
fnp-3326	395	10	varicosities	varicosity	NOUN
fnp-3326	395	11	of	of	ADP
fnp-3326	395	12	the	the	DET
fnp-3326	395	13	vermiform	vermiform	ADJ
fnp-3326	395	14	appendix	appendix	NOUN
fnp-3326	395	15	,	,	PUNCT
fnp-3326	395	16	which	which	PRON
fnp-3326	395	17	showed	show	VERB
fnp-3326	395	18	an	an	DET
fnp-3326	395	19	enriched	enriched	ADJ
fnp-3326	395	20	staining	staining	NOUN
fnp-3326	395	21	for	for	ADP
fnp-3326	395	22	αsyn	αsyn	NOUN
fnp-3326	395	23	in	in	ADP
fnp-3326	395	24	the	the	DET
fnp-3326	395	25	mucosal	mucosal	NOUN
fnp-3326	395	26	plexus	plexus	NOUN
fnp-3326	395	27	.	.	PUNCT
fnp-3326	396	1	furthermore	furthermore	ADV
fnp-3326	396	2	,	,	PUNCT
fnp-3326	396	3	we	we	PRON
fnp-3326	396	4	recently	recently	ADV
fnp-3326	396	5	found	find	VERB
fnp-3326	396	6	that	that	SCONJ
fnp-3326	396	7	the	the	DET
fnp-3326	396	8	vermiform	vermiform	ADJ
fnp-3326	396	9	appendix	appendix	NOUN
fnp-3326	396	10	contains	contain	VERB
fnp-3326	396	11	aggregated	aggregate	VERB
fnp-3326	396	12	and	and	CCONJ
fnp-3326	396	13	truncated	truncate	VERB
fnp-3326	396	14	αsyn	αsyn	NOUN
fnp-3326	396	15	that	that	PRON
fnp-3326	396	16	has	have	VERB
fnp-3326	396	17	the	the	DET
fnp-3326	396	18	propensity	propensity	NOUN
fnp-3326	396	19	to	to	ADP
fnp-3326	396	20	seed	seed	NOUN
fnp-3326	396	21	aggregation	aggregation	NOUN
fnp-3326	396	22	of	of	ADP
fnp-3326	396	23	recombinant	recombinant	ADJ
fnp-3326	396	24	αsyn	αsyn	NOUN
fnp-3326	396	25	in	in	ADP
fnp-3326	396	26	vitro	vitro	X
fnp-3326	397	1	[	[	X
fnp-3326	397	2	62	62	NUM
fnp-3326	397	3	]	]	PUNCT
fnp-3326	397	4	.	.	PUNCT
fnp-3326	398	1	our	our	PRON
fnp-3326	398	2	finding	finding	NOUN
fnp-3326	398	3	of	of	ADP
fnp-3326	398	4	lps	lps	PROPN
fnp-3326	398	5	not	not	PART
fnp-3326	398	6	being	be	AUX
fnp-3326	398	7	able	able	ADJ
fnp-3326	398	8	to	to	PART
fnp-3326	398	9	induce	induce	VERB
fnp-3326	398	10	an	an	DET
fnp-3326	398	11	αsyn	αsyn	ADJ
fnp-3326	398	12	phenotype	phenotype	NOUN
fnp-3326	398	13	in	in	ADP
fnp-3326	398	14	the	the	DET
fnp-3326	398	15	colon	colon	NOUN
fnp-3326	398	16	is	be	AUX
fnp-3326	398	17	in	in	ADP
fnp-3326	398	18	contrast	contrast	NOUN
fnp-3326	398	19	to	to	ADP
fnp-3326	398	20	the	the	DET
fnp-3326	398	21	reports	report	NOUN
fnp-3326	398	22	by	by	ADP
fnp-3326	398	23	kelly	kelly	PROPN
fnp-3326	398	24	and	and	CCONJ
fnp-3326	398	25	colleagues	colleague	NOUN
fnp-3326	398	26	who	who	PRON
fnp-3326	398	27	injected	inject	VERB
fnp-3326	398	28	wild	wild	ADJ
fnp-3326	398	29	type	type	NOUN
fnp-3326	398	30	mice	mouse	NOUN
fnp-3326	398	31	with	with	ADP
fnp-3326	398	32	lps	lps	PROPN
fnp-3326	398	33	and	and	CCONJ
fnp-3326	398	34	observed	observe	VERB
fnp-3326	398	35	an	an	DET
fnp-3326	398	36	immediate	immediate	ADJ
fnp-3326	398	37	and	and	CCONJ
fnp-3326	398	38	progressive	progressive	ADJ
fnp-3326	398	39	increase	increase	NOUN
fnp-3326	398	40	in	in	ADP
fnp-3326	398	41	αsyn	αsyn	PROPN
fnp-3326	398	42	immunoreactivity	immunoreactivity	NOUN
fnp-3326	398	43	in	in	ADP
fnp-3326	398	44	the	the	DET
fnp-3326	398	45	myenteric	myenteric	ADJ
fnp-3326	398	46	ganglia	ganglia	NOUN
fnp-3326	398	47	of	of	ADP
fnp-3326	398	48	the	the	DET
fnp-3326	398	49	large	large	ADJ
fnp-3326	398	50	intestine	intestine	NOUN
fnp-3326	398	51	but	but	CCONJ
fnp-3326	398	52	not	not	PART
fnp-3326	398	53	in	in	ADP
fnp-3326	398	54	the	the	DET
fnp-3326	398	55	small	small	ADJ
fnp-3326	398	56	intestine	intestine	NOUN
fnp-3326	398	57	[	[	X
fnp-3326	398	58	77	77	NUM
fnp-3326	398	59	]	]	PUNCT
fnp-3326	398	60	.	.	PUNCT
fnp-3326	399	1	the	the	DET
fnp-3326	399	2	low	low	PROPN
fnp-3326	399	3	dose	dose	NOUN
fnp-3326	399	4	(	(	PUNCT
fnp-3326	399	5	0.5	0.5	NUM
fnp-3326	399	6	mg	mg	PROPN
fnp-3326	399	7	/	/	SYM
fnp-3326	399	8	kg	kg	PROPN
fnp-3326	399	9	used	use	VERB
fnp-3326	399	10	in	in	ADP
fnp-3326	399	11	our	our	PRON
fnp-3326	399	12	study	study	NOUN
fnp-3326	399	13	versus	versus	ADP
fnp-3326	399	14	2.5	2.5	NUM
fnp-3326	399	15	mg	mg	NOUN
fnp-3326	399	16	/	/	SYM
fnp-3326	399	17	kg	kg	PROPN
fnp-3326	399	18	used	use	VERB
fnp-3326	399	19	by	by	ADP
fnp-3326	399	20	kelly	kelly	PROPN
fnp-3326	399	21	and	and	CCONJ
fnp-3326	399	22	colleagues	colleague	NOUN
fnp-3326	399	23	)	)	PUNCT
fnp-3326	399	24	,	,	PUNCT
fnp-3326	399	25	coupled	couple	VERB
fnp-3326	399	26	with	with	ADP
fnp-3326	399	27	the	the	DET
fnp-3326	399	28	possible	possible	ADJ
fnp-3326	399	29	usage	usage	NOUN
fnp-3326	399	30	of	of	ADP
fnp-3326	399	31	different	different	ADJ
fnp-3326	399	32	bacterial	bacterial	ADJ
fnp-3326	399	33	strains	strain	NOUN
fnp-3326	399	34	to	to	PART
fnp-3326	399	35	generate	generate	VERB
fnp-3326	399	36	lps	lps	PROPN
fnp-3326	399	37	affecting	affect	VERB
fnp-3326	399	38	potency	potency	NOUN
fnp-3326	399	39	and	and	CCONJ
fnp-3326	399	40	pyrogenicity	pyrogenicity	NOUN
fnp-3326	399	41	of	of	ADP
fnp-3326	399	42	lps	lps	PROPN
fnp-3326	399	43	(	(	PUNCT
fnp-3326	399	44	here	here	ADV
fnp-3326	399	45	strain	strain	VERB
fnp-3326	399	46	o55	o55	NOUN
fnp-3326	399	47	:	:	PUNCT
fnp-3326	399	48	b5	b5	PROPN
fnp-3326	399	49	was	be	AUX
fnp-3326	399	50	administered	administer	VERB
fnp-3326	399	51	versus	versus	ADP
fnp-3326	399	52	presumably	presumably	ADV
fnp-3326	399	53	strain	strain	VERB
fnp-3326	399	54	o111	o111	PROPN
fnp-3326	399	55	:	:	PUNCT
fnp-3326	400	1	b4	b4	NOUN
fnp-3326	400	2	used	use	VERB
fnp-3326	400	3	by	by	ADP
fnp-3326	400	4	kelly	kelly	PROPN
fnp-3326	400	5	and	and	CCONJ
fnp-3326	400	6	colleagues	colleague	NOUN
fnp-3326	400	7	and	and	CCONJ
fnp-3326	400	8	others	other	NOUN
fnp-3326	400	9	[	[	X
fnp-3326	400	10	78	78	NUM
fnp-3326	400	11	]	]	PUNCT
fnp-3326	400	12	,	,	PUNCT
fnp-3326	400	13	and	and	CCONJ
fnp-3326	400	14	potential	potential	ADJ
fnp-3326	400	15	effects	effect	NOUN
fnp-3326	400	16	of	of	ADP
fnp-3326	400	17	different	different	ADJ
fnp-3326	400	18	environments	environment	NOUN
fnp-3326	400	19	and	and	CCONJ
fnp-3326	400	20	microbiomes	microbiome	NOUN
fnp-3326	400	21	[	[	X
fnp-3326	400	22	79	79	NUM
fnp-3326	400	23	]	]	PUNCT
fnp-3326	400	24	may	may	AUX
fnp-3326	400	25	contribute	contribute	VERB
fnp-3326	400	26	to	to	ADP
fnp-3326	400	27	this	this	DET
fnp-3326	400	28	discrepancy	discrepancy	NOUN
fnp-3326	400	29	.	.	PUNCT
fnp-3326	401	1	it	it	PRON
fnp-3326	401	2	will	will	AUX
fnp-3326	401	3	be	be	AUX
fnp-3326	401	4	interesting	interesting	ADJ
fnp-3326	401	5	to	to	PART
fnp-3326	401	6	study	study	VERB
fnp-3326	401	7	the	the	DET
fnp-3326	401	8	mentioned	mention	VERB
fnp-3326	401	9	parameters	parameter	NOUN
fnp-3326	401	10	and	and	CCONJ
fnp-3326	401	11	their	their	PRON
fnp-3326	401	12	role	role	NOUN
fnp-3326	401	13	in	in	ADP
fnp-3326	401	14	inducing	induce	VERB
fnp-3326	401	15	αsyn	αsyn	ADJ
fnp-3326	401	16	pathology	pathology	NOUN
fnp-3326	401	17	further	far	ADV
fnp-3326	401	18	in	in	ADP
fnp-3326	401	19	rodent	rodent	ADJ
fnp-3326	401	20	models	model	NOUN
fnp-3326	401	21	and	and	CCONJ
fnp-3326	401	22	explore	explore	VERB
fnp-3326	401	23	how	how	SCONJ
fnp-3326	401	24	this	this	PRON
fnp-3326	401	25	could	could	AUX
fnp-3326	401	26	be	be	AUX
fnp-3326	401	27	translated	translate	VERB
fnp-3326	401	28	to	to	ADP
fnp-3326	401	29	the	the	DET
fnp-3326	401	30	even	even	ADV
fnp-3326	401	31	more	more	ADV
fnp-3326	401	32	heterogeneous	heterogeneous	ADJ
fnp-3326	401	33	human	human	ADJ
fnp-3326	401	34	setting	setting	NOUN
fnp-3326	401	35	.	.	PUNCT
fnp-3326	402	1	similarly	similarly	ADV
fnp-3326	402	2	,	,	PUNCT
fnp-3326	402	3	others	other	NOUN
fnp-3326	402	4	showed	show	VERB
fnp-3326	402	5	that	that	SCONJ
fnp-3326	402	6	employing	employ	VERB
fnp-3326	402	7	a	a	DET
fnp-3326	402	8	sub	sub	ADJ
fnp-3326	402	9	-	-	ADJ
fnp-3326	402	10	chronic	chronic	ADJ
fnp-3326	402	11	0.5	0.5	NUM
fnp-3326	402	12	%	%	NOUN
fnp-3326	402	13	dss	dss	NOUN
fnp-3326	402	14	paradigm	paradigm	NOUN
fnp-3326	402	15	for	for	ADP
fnp-3326	402	16	3	3	NUM
fnp-3326	402	17	weeks	week	NOUN
fnp-3326	402	18	in	in	ADP
fnp-3326	402	19	wild	wild	ADJ
fnp-3326	402	20	type	type	NOUN
fnp-3326	402	21	mice	mouse	NOUN
fnp-3326	402	22	did	do	AUX
fnp-3326	402	23	not	not	PART
fnp-3326	402	24	trigger	trigger	VERB
fnp-3326	402	25	an	an	DET
fnp-3326	402	26	αsyn	αsyn	ADJ
fnp-3326	402	27	pathology	pathology	NOUN
fnp-3326	402	28	in	in	ADP
fnp-3326	402	29	the	the	DET
fnp-3326	402	30	colon	colon	NOUN
fnp-3326	402	31	[	[	NOUN
fnp-3326	402	32	80	80	NUM
fnp-3326	402	33	]	]	PUNCT
fnp-3326	402	34	.	.	PUNCT
fnp-3326	403	1	while	while	SCONJ
fnp-3326	403	2	we	we	PRON
fnp-3326	403	3	have	have	AUX
fnp-3326	403	4	not	not	PART
fnp-3326	403	5	tested	test	VERB
fnp-3326	403	6	this	this	DET
fnp-3326	403	7	particular	particular	ADJ
fnp-3326	403	8	sub	sub	ADJ
fnp-3326	403	9	-	-	ADJ
fnp-3326	403	10	chronic	chronic	ADJ
fnp-3326	403	11	dss	dss	NOUN
fnp-3326	403	12	colitis	colitis	NOUN
fnp-3326	403	13	paradigm	paradigm	NOUN
fnp-3326	403	14	and	and	CCONJ
fnp-3326	403	15	instead	instead	ADV
fnp-3326	403	16	had	have	AUX
fnp-3326	403	17	administered	administer	VERB
fnp-3326	403	18	5	5	NUM
fnp-3326	403	19	%	%	NOUN
fnp-3326	403	20	dss	dss	NOUN
fnp-3326	403	21	acutely	acutely	ADV
fnp-3326	403	22	to	to	ADP
fnp-3326	403	23	the	the	DET
fnp-3326	403	24	wild	wild	ADJ
fnp-3326	403	25	type	type	NOUN
fnp-3326	403	26	mice	mouse	NOUN
fnp-3326	403	27	(	(	PUNCT
fnp-3326	403	28	fig	fig	NOUN
fnp-3326	403	29	.	.	PUNCT
fnp-3326	404	1	2c	2c	NOUN
fnp-3326	404	2	)	)	PUNCT
fnp-3326	404	3	,	,	PUNCT
fnp-3326	404	4	the	the	DET
fnp-3326	404	5	data	datum	NOUN
fnp-3326	404	6	by	by	ADP
fnp-3326	404	7	garrido	garrido	PROPN
fnp-3326	404	8	-	-	PUNCT
fnp-3326	404	9	gil	gil	PROPN
fnp-3326	404	10	and	and	CCONJ
fnp-3326	404	11	colleagues	colleague	NOUN
fnp-3326	404	12	may	may	AUX
fnp-3326	404	13	corroborate	corroborate	VERB
fnp-3326	404	14	our	our	PRON
fnp-3326	404	15	results	result	NOUN
fnp-3326	404	16	which	which	PRON
fnp-3326	404	17	show	show	VERB
fnp-3326	404	18	in	in	ADP
fnp-3326	404	19	αsyn	αsyn	ADJ
fnp-3326	404	20	transgenic	transgenic	NOUN
fnp-3326	404	21	mice	mouse	NOUN
fnp-3326	404	22	that	that	SCONJ
fnp-3326	404	23	a	a	DET
fnp-3326	404	24	certain	certain	ADJ
fnp-3326	404	25	dss	dss	NOUN
fnp-3326	404	26	dose	dose	NOUN
fnp-3326	404	27	and	and	CCONJ
fnp-3326	404	28	severity	severity	NOUN
fnp-3326	404	29	of	of	ADP
fnp-3326	404	30	inflammation	inflammation	NOUN
fnp-3326	404	31	is	be	AUX
fnp-3326	404	32	required	require	VERB
fnp-3326	404	33	in	in	ADP
fnp-3326	404	34	order	order	NOUN
fnp-3326	404	35	to	to	PART
fnp-3326	404	36	induce	induce	VERB
fnp-3326	404	37	accumulation	accumulation	NOUN
fnp-3326	404	38	of	of	ADP
fnp-3326	404	39	αsyn	αsyn	NOUN
fnp-3326	404	40	in	in	ADP
fnp-3326	404	41	the	the	DET
fnp-3326	404	42	submucosal	submucosal	NOUN
fnp-3326	404	43	plexus	plexus	NOUN
fnp-3326	404	44	(	(	PUNCT
fnp-3326	404	45	fig	fig	NOUN
fnp-3326	404	46	.	.	PUNCT
fnp-3326	404	47	2a	2a	NUM
fnp-3326	404	48	)	)	PUNCT
fnp-3326	404	49	.	.	PUNCT
fnp-3326	405	1	what	what	PRON
fnp-3326	405	2	could	could	AUX
fnp-3326	405	3	be	be	AUX
fnp-3326	405	4	a	a	DET
fnp-3326	405	5	functional	functional	ADJ
fnp-3326	405	6	role	role	NOUN
fnp-3326	405	7	of	of	ADP
fnp-3326	405	8	the	the	DET
fnp-3326	405	9	αsyn	αsyn	ADJ
fnp-3326	405	10	species	specie	NOUN
fnp-3326	405	11	found	find	VERB
fnp-3326	405	12	in	in	ADP
fnp-3326	405	13	abundance	abundance	NOUN
fnp-3326	405	14	in	in	ADP
fnp-3326	405	15	the	the	DET
fnp-3326	405	16	gut	gut	NOUN
fnp-3326	405	17	wall	wall	NOUN
fnp-3326	405	18	?	?	PUNCT
fnp-3326	406	1	monomeric	monomeric	ADJ
fnp-3326	406	2	and	and	CCONJ
fnp-3326	406	3	oligomeric	oligomeric	ADJ
fnp-3326	406	4	αsyn	αsyn	ADJ
fnp-3326	406	5	species	specie	NOUN
fnp-3326	406	6	reportedly	reportedly	ADV
fnp-3326	406	7	act	act	VERB
fnp-3326	406	8	as	as	ADP
fnp-3326	406	9	chemoattractants	chemoattractant	NOUN
fnp-3326	406	10	for	for	ADP
fnp-3326	406	11	neutrophils	neutrophil	NOUN
fnp-3326	406	12	and	and	CCONJ
fnp-3326	406	13	monocytes	monocyte	NOUN
fnp-3326	406	14	,	,	PUNCT
fnp-3326	406	15	enhancing	enhance	VERB
fnp-3326	406	16	the	the	DET
fnp-3326	406	17	maturation	maturation	NOUN
fnp-3326	406	18	of	of	ADP
fnp-3326	406	19	dendritic	dendritic	ADJ
fnp-3326	406	20	cells	cell	NOUN
fnp-3326	406	21	in	in	ADP
fnp-3326	406	22	the	the	DET
fnp-3326	406	23	ens	ens	NOUN
fnp-3326	406	24	[	[	X
fnp-3326	406	25	22,81	22,81	NUM
fnp-3326	406	26	]	]	X
fnp-3326	406	27	.	.	PUNCT
fnp-3326	407	1	with	with	ADP
fnp-3326	407	2	such	such	DET
fnp-3326	407	3	a	a	DET
fnp-3326	407	4	role	role	NOUN
fnp-3326	407	5	in	in	ADP
fnp-3326	407	6	intestinal	intestinal	ADJ
fnp-3326	407	7	immunity	immunity	NOUN
fnp-3326	407	8	,	,	PUNCT
fnp-3326	407	9	it	it	PRON
fnp-3326	407	10	is	be	AUX
fnp-3326	407	11	possible	possible	ADJ
fnp-3326	407	12	that	that	SCONJ
fnp-3326	407	13	the	the	DET
fnp-3326	407	14	tissue	tissue	NOUN
fnp-3326	407	15	destruction	destruction	NOUN
fnp-3326	407	16	induced	induce	VERB
fnp-3326	407	17	by	by	ADP
fnp-3326	407	18	dss	dss	NOUN
fnp-3326	407	19	in	in	ADP
fnp-3326	407	20	the	the	DET
fnp-3326	407	21	present	present	ADJ
fnp-3326	407	22	study	study	NOUN
fnp-3326	407	23	led	lead	VERB
fnp-3326	407	24	to	to	ADP
fnp-3326	407	25	release	release	NOUN
fnp-3326	407	26	of	of	ADP
fnp-3326	407	27	αsyn	αsyn	NOUN
fnp-3326	407	28	,	,	PUNCT
fnp-3326	407	29	which	which	PRON
fnp-3326	407	30	perhaps	perhaps	ADV
fnp-3326	407	31	served	serve	VERB
fnp-3326	407	32	as	as	ADP
fnp-3326	407	33	a	a	DET
fnp-3326	407	34	chemoattractant	chemoattractant	NOUN
fnp-3326	407	35	for	for	ADP
fnp-3326	407	36	monocytes	monocyte	NOUN
fnp-3326	407	37	.	.	PUNCT
fnp-3326	408	1	the	the	DET
fnp-3326	408	2	increased	increase	VERB
fnp-3326	408	3	abundance	abundance	NOUN
fnp-3326	408	4	of	of	ADP
fnp-3326	408	5	αsyn	αsyn	NOUN
fnp-3326	408	6	and	and	CCONJ
fnp-3326	408	7	altered	alter	VERB
fnp-3326	408	8	intestinal	intestinal	ADJ
fnp-3326	408	9	permeability	permeability	NOUN
fnp-3326	408	10	,	,	PUNCT
fnp-3326	408	11	along	along	ADP
fnp-3326	408	12	with	with	ADP
fnp-3326	408	13	the	the	DET
fnp-3326	408	14	dss	dss	NOUN
fnp-3326	408	15	-	-	PUNCT
fnp-3326	408	16	evoked	evoke	VERB
fnp-3326	408	17	inflammatory	inflammatory	ADJ
fnp-3326	408	18	response	response	NOUN
fnp-3326	408	19	may	may	AUX
fnp-3326	408	20	have	have	AUX
fnp-3326	408	21	provided	provide	VERB
fnp-3326	408	22	an	an	DET
fnp-3326	408	23	enabling	enable	VERB
fnp-3326	408	24	milieu	milieu	NOUN
fnp-3326	408	25	allowing	allow	VERB
fnp-3326	408	26	further	further	ADJ
fnp-3326	408	27	αsyn	αsyn	ADJ
fnp-3326	408	28	accumulation	accumulation	NOUN
fnp-3326	408	29	in	in	ADP
fnp-3326	408	30	the	the	DET
fnp-3326	408	31	ens	ens	NOUN
fnp-3326	408	32	of	of	ADP
fnp-3326	408	33	the	the	DET
fnp-3326	408	34	colon	colon	NOUN
fnp-3326	408	35	[	[	NOUN
fnp-3326	408	36	77	77	NUM
fnp-3326	408	37	]	]	PUNCT
fnp-3326	408	38	.	.	PUNCT
fnp-3326	409	1	macrophages	macrophage	NOUN
fnp-3326	409	2	and	and	CCONJ
fnp-3326	409	3	other	other	ADJ
fnp-3326	409	4	immune	immune	ADJ
fnp-3326	409	5	cells	cell	NOUN
fnp-3326	409	6	are	be	AUX
fnp-3326	409	7	also	also	ADV
fnp-3326	409	8	regulated	regulate	VERB
fnp-3326	409	9	by	by	ADP
fnp-3326	409	10	several	several	ADJ
fnp-3326	409	11	genes	gene	NOUN
fnp-3326	409	12	including	include	VERB
fnp-3326	409	13	lrrk2	lrrk2	PROPN
fnp-3326	409	14	,	,	PUNCT
fnp-3326	409	15	an	an	DET
fnp-3326	409	16	established	establish	VERB
fnp-3326	409	17	risk	risk	NOUN
fnp-3326	409	18	gene	gene	NOUN
fnp-3326	409	19	for	for	ADP
fnp-3326	409	20	pd	pd	PROPN
fnp-3326	409	21	and	and	CCONJ
fnp-3326	409	22	ibd	ibd	PROPN
fnp-3326	409	23	.	.	PUNCT
fnp-3326	410	1	it	it	PRON
fnp-3326	410	2	will	will	AUX
fnp-3326	410	3	be	be	AUX
fnp-3326	410	4	interesting	interesting	ADJ
fnp-3326	410	5	to	to	PART
fnp-3326	410	6	explore	explore	VERB
fnp-3326	410	7	how	how	SCONJ
fnp-3326	410	8	mutations	mutation	NOUN
fnp-3326	410	9	in	in	ADP
fnp-3326	410	10	genes	gene	NOUN
fnp-3326	410	11	that	that	PRON
fnp-3326	410	12	control	control	VERB
fnp-3326	410	13	autophagy	autophagy	VERB
fnp-3326	410	14	,	,	PUNCT
fnp-3326	410	15	including	include	VERB
fnp-3326	410	16	the	the	DET
fnp-3326	410	17	lrrk2	lrrk2	NOUN
fnp-3326	410	18	gene	gene	NOUN
fnp-3326	410	19	,	,	PUNCT
fnp-3326	410	20	influence	influence	VERB
fnp-3326	410	21	the	the	DET
fnp-3326	410	22	handling	handling	NOUN
fnp-3326	410	23	of	of	ADP
fnp-3326	410	24	αsyn	αsyn	NOUN
fnp-3326	410	25	by	by	ADP
fnp-3326	410	26	macrophages	macrophage	NOUN
fnp-3326	410	27	that	that	PRON
fnp-3326	410	28	invade	invade	VERB
fnp-3326	410	29	the	the	DET
fnp-3326	410	30	inflamed	inflamed	ADJ
fnp-3326	410	31	colon	colon	NOUN
fnp-3326	410	32	in	in	ADP
fnp-3326	410	33	our	our	PRON
fnp-3326	410	34	dss	dss	NOUN
fnp-3326	410	35	colitis	colitis	NOUN
fnp-3326	410	36	paradigm	paradigm	NOUN
fnp-3326	410	37	.	.	PUNCT
fnp-3326	411	1	despite	despite	SCONJ
fnp-3326	411	2	the	the	DET
fnp-3326	411	3	intriguing	intriguing	ADJ
fnp-3326	411	4	translational	translational	ADJ
fnp-3326	411	5	aspect	aspect	NOUN
fnp-3326	411	6	of	of	ADP
fnp-3326	411	7	our	our	PRON
fnp-3326	411	8	finding	finding	NOUN
fnp-3326	411	9	in	in	ADP
fnp-3326	411	10	the	the	DET
fnp-3326	411	11	dss	dss	NOUN
fnp-3326	411	12	paradigm	paradigm	NOUN
fnp-3326	411	13	,	,	PUNCT
fnp-3326	411	14	others	other	NOUN
fnp-3326	411	15	have	have	AUX
fnp-3326	411	16	very	very	ADV
fnp-3326	411	17	recently	recently	ADV
fnp-3326	411	18	reported	report	VERB
fnp-3326	411	19	that	that	SCONJ
fnp-3326	411	20	dss	dss	NOUN
fnp-3326	411	21	colitis	colitis	NOUN
fnp-3326	411	22	in	in	ADP
fnp-3326	411	23	mice	mouse	NOUN
fnp-3326	411	24	down	down	ADP
fnp-3326	411	25	-	-	PUNCT
fnp-3326	411	26	regulates	regulate	VERB
fnp-3326	411	27	the	the	DET
fnp-3326	411	28	expression	expression	NOUN
fnp-3326	411	29	of	of	ADP
fnp-3326	411	30	enteric	enteric	ADJ
fnp-3326	411	31	αsyn	αsyn	NOUN
fnp-3326	411	32	on	on	ADP
fnp-3326	411	33	protein	protein	NOUN
fnp-3326	411	34	levels	level	NOUN
fnp-3326	411	35	in	in	ADP
fnp-3326	411	36	vivo	vivo	NOUN
fnp-3326	411	37	[	[	X
fnp-3326	411	38	82,83	82,83	NUM
fnp-3326	411	39	]	]	PUNCT
fnp-3326	411	40	.	.	PUNCT
fnp-3326	412	1	this	this	PRON
fnp-3326	412	2	is	be	AUX
fnp-3326	412	3	in	in	ADP
fnp-3326	412	4	contrast	contrast	NOUN
fnp-3326	412	5	to	to	ADP
fnp-3326	412	6	our	our	PRON
fnp-3326	412	7	immunofluorescence	immunofluorescence	NOUN
fnp-3326	412	8	(	(	PUNCT
fnp-3326	412	9	i.e.	i.e.	X
fnp-3326	412	10	,	,	PUNCT
fnp-3326	412	11	increased	increase	VERB
fnp-3326	412	12	accumulation	accumulation	NOUN
fnp-3326	412	13	of	of	ADP
fnp-3326	412	14	αsyn	αsyn	NOUN
fnp-3326	412	15	in	in	ADP
fnp-3326	412	16	submucosal	submucosal	NOUN
fnp-3326	412	17	plexus	plexus	NOUN
fnp-3326	412	18	upon	upon	SCONJ
fnp-3326	412	19	dss	dss	NOUN
fnp-3326	412	20	colitis	colitis	NOUN
fnp-3326	412	21	;	;	PUNCT
fnp-3326	412	22	fig	fig	NOUN
fnp-3326	412	23	.	.	PUNCT
fnp-3326	413	1	2	2	NUM
fnp-3326	413	2	,	,	PUNCT
fnp-3326	413	3	3	3	NUM
fnp-3326	413	4	,	,	PUNCT
fnp-3326	413	5	and	and	CCONJ
fnp-3326	413	6	4	4	NUM
fnp-3326	413	7	)	)	PUNCT
fnp-3326	414	1	and	and	CCONJ
fnp-3326	414	2	gene	gene	NOUN
fnp-3326	414	3	expression	expression	NOUN
fnp-3326	414	4	data	datum	NOUN
fnp-3326	414	5	(	(	PUNCT
fnp-3326	414	6	e.g.	e.g.	ADV
fnp-3326	414	7	,	,	PUNCT
fnp-3326	414	8	no	no	DET
fnp-3326	414	9	change	change	NOUN
fnp-3326	414	10	in	in	ADP
fnp-3326	414	11	endogenous	endogenous	ADJ
fnp-3326	414	12	and	and	CCONJ
fnp-3326	414	13	transgenic	transgenic	VERB
fnp-3326	414	14	αsyn	αsyn	NOUN
fnp-3326	414	15	upon	upon	SCONJ
fnp-3326	414	16	dss	dss	NOUN
fnp-3326	414	17	colitis	colitis	NOUN
fnp-3326	414	18	;	;	PUNCT
fnp-3326	414	19	suppl	suppl	PROPN
fnp-3326	414	20	.	.	PUNCT
fnp-3326	414	21	fig	fig	PROPN
fnp-3326	414	22	.	.	PUNCT
fnp-3326	415	1	3	3	NUM
fnp-3326	415	2	)	)	PUNCT
fnp-3326	415	3	in	in	ADP
fnp-3326	415	4	the	the	DET
fnp-3326	415	5	same	same	ADJ
fnp-3326	415	6	paradigm	paradigm	NOUN
fnp-3326	415	7	and	and	CCONJ
fnp-3326	415	8	may	may	AUX
fnp-3326	415	9	reflect	reflect	VERB
fnp-3326	415	10	the	the	DET
fnp-3326	415	11	well	well	ADV
fnp-3326	415	12	-	-	PUNCT
fnp-3326	415	13	known	know	VERB
fnp-3326	415	14	lab	lab	NOUN
fnp-3326	415	15	-	-	PUNCT
fnp-3326	415	16	to	to	ADP
fnp-3326	415	17	-	-	PUNCT
fnp-3326	415	18	lab	lab	NOUN
fnp-3326	415	19	variability	variability	NOUN
fnp-3326	415	20	that	that	PRON
fnp-3326	415	21	can	can	AUX
fnp-3326	415	22	occur	occur	VERB
fnp-3326	415	23	for	for	ADP
fnp-3326	415	24	the	the	DET
fnp-3326	415	25	dss	dss	NOUN
fnp-3326	415	26	models	model	NOUN
fnp-3326	415	27	[	[	X
fnp-3326	415	28	84	84	NUM
fnp-3326	415	29	]	]	PUNCT
fnp-3326	415	30	.	.	PUNCT
fnp-3326	416	1	perhaps	perhaps	ADV
fnp-3326	416	2	the	the	DET
fnp-3326	416	3	most	most	ADV
fnp-3326	416	4	striking	striking	ADJ
fnp-3326	416	5	finding	finding	NOUN
fnp-3326	416	6	in	in	ADP
fnp-3326	416	7	our	our	PRON
fnp-3326	416	8	study	study	NOUN
fnp-3326	416	9	was	be	AUX
fnp-3326	416	10	that	that	SCONJ
fnp-3326	416	11	a	a	DET
fnp-3326	416	12	single	single	ADJ
fnp-3326	416	13	period	period	NOUN
fnp-3326	416	14	of	of	ADP
fnp-3326	416	15	dss	dss	NOUN
fnp-3326	416	16	-	-	PUNCT
fnp-3326	416	17	induced	induce	VERB
fnp-3326	416	18	colitis	colitis	NOUN
fnp-3326	416	19	at	at	ADP
fnp-3326	416	20	a	a	DET
fnp-3326	416	21	young	young	ADJ
fnp-3326	416	22	age	age	NOUN
fnp-3326	416	23	led	lead	VERB
fnp-3326	416	24	to	to	ADP
fnp-3326	416	25	an	an	DET
fnp-3326	416	26	exacerbation	exacerbation	NOUN
fnp-3326	416	27	of	of	ADP
fnp-3326	416	28	αsyn	αsyn	ADJ
fnp-3326	416	29	pathology	pathology	NOUN
fnp-3326	416	30	in	in	ADP
fnp-3326	416	31	the	the	DET
fnp-3326	416	32	brain	brain	NOUN
fnp-3326	416	33	of	of	ADP
fnp-3326	416	34	αsyn	αsyn	ADJ
fnp-3326	416	35	transgenic	transgenic	NOUN
fnp-3326	416	36	mice	mouse	NOUN
fnp-3326	416	37	much	much	ADV
fnp-3326	416	38	later	later	ADV
fnp-3326	416	39	in	in	ADP
fnp-3326	416	40	life	life	NOUN
fnp-3326	416	41	(	(	PUNCT
fnp-3326	416	42	fig	fig	NOUN
fnp-3326	416	43	.	.	PUNCT
fnp-3326	416	44	5	5	NUM
fnp-3326	416	45	)	)	PUNCT
fnp-3326	416	46	.	.	PUNCT
fnp-3326	417	1	how	how	SCONJ
fnp-3326	417	2	does	do	AUX
fnp-3326	417	3	severe	severe	ADJ
fnp-3326	417	4	αsyn	αsyn	ADJ
fnp-3326	417	5	inclusion	inclusion	NOUN
fnp-3326	417	6	pathology	pathology	NOUN
fnp-3326	417	7	develop	develop	VERB
fnp-3326	417	8	in	in	ADP
fnp-3326	417	9	the	the	DET
fnp-3326	417	10	brains	brain	NOUN
fnp-3326	417	11	of	of	ADP
fnp-3326	417	12	these	these	DET
fnp-3326	417	13	mice	mouse	NOUN
fnp-3326	417	14	?	?	PUNCT
fnp-3326	418	1	one	one	NUM
fnp-3326	418	2	hypothesis	hypothesis	NOUN
fnp-3326	418	3	is	be	AUX
fnp-3326	418	4	that	that	SCONJ
fnp-3326	418	5	the	the	DET
fnp-3326	418	6	brain	brain	NOUN
fnp-3326	418	7	αsyn	αsyn	NOUN
fnp-3326	418	8	pathology	pathology	NOUN
fnp-3326	418	9	observed	observe	VERB
fnp-3326	418	10	in	in	ADP
fnp-3326	418	11	this	this	DET
fnp-3326	418	12	study	study	NOUN
fnp-3326	418	13	could	could	AUX
fnp-3326	418	14	be	be	AUX
fnp-3326	418	15	due	due	ADJ
fnp-3326	418	16	to	to	ADP
fnp-3326	418	17	direct	direct	ADJ
fnp-3326	418	18	effects	effect	NOUN
fnp-3326	418	19	of	of	ADP
fnp-3326	418	20	peripheral	peripheral	ADJ
fnp-3326	418	21	immune	immune	ADJ
fnp-3326	418	22	activation	activation	NOUN
fnp-3326	418	23	on	on	ADP
fnp-3326	418	24	the	the	DET
fnp-3326	418	25	brain	brain	NOUN
fnp-3326	418	26	and	and	CCONJ
fnp-3326	418	27	that	that	SCONJ
fnp-3326	418	28	certain	certain	ADJ
fnp-3326	418	29	peripheral	peripheral	ADJ
fnp-3326	418	30	triggers	trigger	NOUN
fnp-3326	418	31	can	can	AUX
fnp-3326	418	32	directly	directly	ADV
fnp-3326	418	33	affect	affect	VERB
fnp-3326	418	34	microglial	microglial	ADJ
fnp-3326	418	35	activity	activity	NOUN
fnp-3326	418	36	.	.	PUNCT
fnp-3326	419	1	for	for	ADP
fnp-3326	419	2	instance	instance	NOUN
fnp-3326	419	3	,	,	PUNCT
fnp-3326	419	4	short	short	ADJ
fnp-3326	419	5	-	-	PUNCT
fnp-3326	419	6	chain	chain	NOUN
fnp-3326	419	7	fatty	fatty	NOUN
fnp-3326	419	8	acids	acid	NOUN
fnp-3326	419	9	derived	derive	VERB
fnp-3326	419	10	from	from	ADP
fnp-3326	419	11	gut	gut	NOUN
fnp-3326	419	12	microbiota	microbiota	NOUN
fnp-3326	419	13	appear	appear	VERB
fnp-3326	419	14	to	to	PART
fnp-3326	419	15	influence	influence	VERB
fnp-3326	419	16	function	function	NOUN
fnp-3326	419	17	and	and	CCONJ
fnp-3326	419	18	maturation	maturation	NOUN
fnp-3326	419	19	of	of	ADP
fnp-3326	419	20	microglia	microglia	NOUN
fnp-3326	419	21	in	in	ADP
fnp-3326	419	22	the	the	DET
fnp-3326	419	23	mouse	mouse	NOUN
fnp-3326	419	24	brain	brain	NOUN
fnp-3326	419	25	[	[	X
fnp-3326	419	26	85	85	NUM
fnp-3326	419	27	]	]	PUNCT
fnp-3326	419	28	and	and	CCONJ
fnp-3326	419	29	inflammatory	inflammatory	ADJ
fnp-3326	419	30	mediators	mediator	NOUN
fnp-3326	419	31	released	release	VERB
fnp-3326	419	32	by	by	ADP
fnp-3326	419	33	gut	gut	NOUN
fnp-3326	419	34	microbiota	microbiota	NOUN
fnp-3326	419	35	into	into	ADP
fnp-3326	419	36	the	the	DET
fnp-3326	419	37	bloodstream	bloodstream	NOUN
fnp-3326	419	38	have	have	AUX
fnp-3326	419	39	been	be	AUX
fnp-3326	419	40	suggested	suggest	VERB
fnp-3326	419	41	to	to	PART
fnp-3326	419	42	induce	induce	VERB
fnp-3326	419	43	brain	brain	NOUN
fnp-3326	419	44	pathology	pathology	NOUN
fnp-3326	419	45	and	and	CCONJ
fnp-3326	419	46	behavioral	behavioral	ADJ
fnp-3326	419	47	changes	change	NOUN
fnp-3326	419	48	in	in	ADP
fnp-3326	419	49	an	an	DET
fnp-3326	419	50	αsyn	αsyn	ADJ
fnp-3326	419	51	transgenic	transgenic	NOUN
fnp-3326	419	52	mouse	mouse	NOUN
fnp-3326	419	53	model	model	NOUN
fnp-3326	419	54	[	[	X
fnp-3326	419	55	86	86	NUM
fnp-3326	419	56	]	]	PUNCT
fnp-3326	419	57	.	.	PUNCT
fnp-3326	420	1	moreover	moreover	ADV
fnp-3326	420	2	,	,	PUNCT
fnp-3326	420	3	rats	rat	NOUN
fnp-3326	420	4	and	and	CCONJ
fnp-3326	420	5	nematodes	nematode	NOUN
fnp-3326	420	6	have	have	AUX
fnp-3326	420	7	been	be	AUX
fnp-3326	420	8	reported	report	VERB
fnp-3326	420	9	to	to	PART
fnp-3326	420	10	develop	develop	VERB
fnp-3326	420	11	αsyn	αsyn	ADJ
fnp-3326	420	12	inclusions	inclusion	NOUN
fnp-3326	420	13	after	after	ADP
fnp-3326	420	14	exposure	exposure	NOUN
fnp-3326	420	15	to	to	ADP
fnp-3326	420	16	the	the	DET
fnp-3326	420	17	bacterial	bacterial	ADJ
fnp-3326	420	18	amyloid	amyloid	NOUN
fnp-3326	420	19	protein	protein	NOUN
fnp-3326	420	20	curli	curli	NOUN
fnp-3326	420	21	,	,	PUNCT
fnp-3326	420	22	a	a	DET
fnp-3326	420	23	protein	protein	NOUN
fnp-3326	420	24	which	which	PRON
fnp-3326	420	25	stimulates	stimulate	VERB
fnp-3326	420	26	microgliosis	microgliosis	NOUN
fnp-3326	420	27	,	,	PUNCT
fnp-3326	420	28	astrogliosis	astrogliosis	NOUN
fnp-3326	420	29	,	,	PUNCT
fnp-3326	420	30	and	and	CCONJ
fnp-3326	420	31	secretion	secretion	NOUN
fnp-3326	420	32	of	of	ADP
fnp-3326	420	33	il-6	il-6	NOUN
fnp-3326	420	34	and	and	CCONJ
fnp-3326	420	35	tnf	tnf	PROPN
fnp-3326	421	1	[	[	X
fnp-3326	421	2	87	87	NUM
fnp-3326	421	3	]	]	PUNCT
fnp-3326	421	4	.	.	PUNCT
fnp-3326	422	1	intriguingly	intriguingly	ADV
fnp-3326	422	2	,	,	PUNCT
fnp-3326	422	3	a	a	DET
fnp-3326	422	4	recent	recent	ADJ
fnp-3326	422	5	study	study	NOUN
fnp-3326	422	6	reported	report	VERB
fnp-3326	422	7	that	that	SCONJ
fnp-3326	422	8	peripherally	peripherally	ADV
fnp-3326	422	9	applied	apply	VERB
fnp-3326	422	10	inflammatory	inflammatory	ADJ
fnp-3326	422	11	stimuli	stimulus	NOUN
fnp-3326	422	12	induce	induce	VERB
fnp-3326	422	13	acute	acute	ADJ
fnp-3326	422	14	immune	immune	ADJ
fnp-3326	422	15	training	training	NOUN
fnp-3326	422	16	(	(	PUNCT
fnp-3326	422	17	that	that	PRON
fnp-3326	422	18	exacerbates	exacerbate	VERB
fnp-3326	422	19	β	β	NOUN
fnp-3326	422	20	-	-	ADJ
fnp-3326	422	21	amyloid	amyloid	ADJ
fnp-3326	422	22	pathology	pathology	NOUN
fnp-3326	422	23	)	)	PUNCT
fnp-3326	422	24	and	and	CCONJ
fnp-3326	422	25	immune	immune	ADJ
fnp-3326	422	26	tolerance	tolerance	NOUN
fnp-3326	422	27	in	in	ADP
fnp-3326	422	28	the	the	DET
fnp-3326	422	29	brain	brain	NOUN
fnp-3326	422	30	that	that	PRON
fnp-3326	422	31	reprograms	reprogram	VERB
fnp-3326	422	32	microglia	microglia	PROPN
fnp-3326	422	33	,	,	PUNCT
fnp-3326	422	34	an	an	DET
fnp-3326	422	35	effect	effect	NOUN
fnp-3326	422	36	which	which	PRON
fnp-3326	422	37	can	can	AUX
fnp-3326	422	38	persist	persist	VERB
fnp-3326	422	39	for	for	ADP
fnp-3326	422	40	at	at	ADV
fnp-3326	422	41	least	least	ADV
fnp-3326	422	42	six	six	NUM
fnp-3326	422	43	months	month	NOUN
fnp-3326	422	44	[	[	X
fnp-3326	422	45	88	88	NUM
fnp-3326	422	46	]	]	PUNCT
fnp-3326	422	47	.	.	PUNCT
fnp-3326	423	1	whether	whether	SCONJ
fnp-3326	423	2	this	this	PRON
fnp-3326	423	3	is	be	AUX
fnp-3326	423	4	a	a	DET
fnp-3326	423	5	relevant	relevant	ADJ
fnp-3326	423	6	mechanism	mechanism	NOUN
fnp-3326	423	7	in	in	ADP
fnp-3326	423	8	the	the	DET
fnp-3326	423	9	dss	dss	NOUN
fnp-3326	423	10	paradigm	paradigm	NOUN
fnp-3326	423	11	needs	need	VERB
fnp-3326	423	12	to	to	PART
fnp-3326	423	13	be	be	AUX
fnp-3326	423	14	explored	explore	VERB
fnp-3326	423	15	.	.	PUNCT
fnp-3326	424	1	another	another	DET
fnp-3326	424	2	hypothesis	hypothesis	NOUN
fnp-3326	424	3	is	be	AUX
fnp-3326	424	4	that	that	SCONJ
fnp-3326	424	5	the	the	DET
fnp-3326	424	6	observed	observed	ADJ
fnp-3326	424	7	brain	brain	NOUN
fnp-3326	424	8	αsyn	αsyn	PROPN
fnp-3326	424	9	pathology	pathology	NOUN
fnp-3326	424	10	may	may	AUX
fnp-3326	424	11	have	have	AUX
fnp-3326	424	12	accumulated	accumulate	VERB
fnp-3326	424	13	as	as	ADP
fnp-3326	424	14	a	a	DET
fnp-3326	424	15	consequence	consequence	NOUN
fnp-3326	424	16	of	of	ADP
fnp-3326	424	17	the	the	DET
fnp-3326	424	18	transfer	transfer	NOUN
fnp-3326	424	19	of	of	ADP
fnp-3326	424	20	pathogenic	pathogenic	ADJ
fnp-3326	424	21	αsyn	αsyn	NOUN
fnp-3326	424	22	seeds	seed	NOUN
fnp-3326	424	23	from	from	ADP
fnp-3326	424	24	the	the	DET
fnp-3326	424	25	gut	gut	NOUN
fnp-3326	424	26	via	via	ADP
fnp-3326	424	27	the	the	DET
fnp-3326	424	28	vagal	vagal	ADJ
fnp-3326	424	29	nerve	nerve	NOUN
fnp-3326	424	30	.	.	PUNCT
fnp-3326	425	1	several	several	ADJ
fnp-3326	425	2	experimental	experimental	ADJ
fnp-3326	425	3	studies	study	NOUN
fnp-3326	425	4	have	have	AUX
fnp-3326	425	5	demonstrated	demonstrate	VERB
fnp-3326	425	6	that	that	SCONJ
fnp-3326	425	7	pathogenic	pathogenic	ADJ
fnp-3326	425	8	αsyn	αsyn	NOUN
fnp-3326	425	9	seeds	seed	NOUN
fnp-3326	425	10	can	can	AUX
fnp-3326	425	11	be	be	AUX
fnp-3326	425	12	transferred	transfer	VERB
fnp-3326	425	13	from	from	ADP
fnp-3326	425	14	the	the	DET
fnp-3326	425	15	peripheral	peripheral	NOUN
fnp-3326	425	16	to	to	ADP
fnp-3326	425	17	the	the	DET
fnp-3326	425	18	central	central	ADJ
fnp-3326	425	19	nervous	nervous	ADJ
fnp-3326	425	20	system	system	NOUN
fnp-3326	425	21	.	.	PUNCT
fnp-3326	426	1	aggregated	aggregate	VERB
fnp-3326	426	2	recombinant	recombinant	ADJ
fnp-3326	426	3	αsyn	αsyn	NOUN
fnp-3326	426	4	injected	inject	VERB
fnp-3326	426	5	intraperitoneally	intraperitoneally	ADV
fnp-3326	426	6	,	,	PUNCT
fnp-3326	426	7	intramuscularly	intramuscularly	ADV
fnp-3326	426	8	or	or	CCONJ
fnp-3326	426	9	into	into	ADP
fnp-3326	426	10	the	the	DET
fnp-3326	426	11	gastric	gastric	ADJ
fnp-3326	426	12	wall	wall	NOUN
fnp-3326	426	13	of	of	ADP
fnp-3326	426	14	certain	certain	ADJ
fnp-3326	426	15	mouse	mouse	NOUN
fnp-3326	426	16	models	model	NOUN
fnp-3326	426	17	of	of	ADP
fnp-3326	426	18	pd	pd	PROPN
fnp-3326	426	19	results	result	NOUN
fnp-3326	426	20	in	in	ADP
fnp-3326	426	21	αsyn	αsyn	ADJ
fnp-3326	426	22	inclusions	inclusion	NOUN
fnp-3326	426	23	in	in	ADP
fnp-3326	426	24	the	the	DET
fnp-3326	426	25	brain	brain	NOUN
fnp-3326	427	1	[	[	X
fnp-3326	427	2	16,89	16,89	NUM
fnp-3326	427	3	]	]	PUNCT
fnp-3326	427	4	.	.	PUNCT
fnp-3326	428	1	data	datum	NOUN
fnp-3326	428	2	from	from	ADP
fnp-3326	428	3	animals	animal	NOUN
fnp-3326	428	4	injected	inject	VERB
fnp-3326	428	5	with	with	ADP
fnp-3326	428	6	recombinant	recombinant	ADJ
fnp-3326	428	7	αsyn	αsyn	ADJ
fnp-3326	428	8	protein	protein	NOUN
fnp-3326	428	9	in	in	ADP
fnp-3326	428	10	the	the	DET
fnp-3326	428	11	gut	gut	NOUN
fnp-3326	428	12	wall	wall	NOUN
fnp-3326	428	13	or	or	CCONJ
fnp-3326	428	14	viral	viral	ADJ
fnp-3326	428	15	vectors	vector	NOUN
fnp-3326	428	16	expressing	express	VERB
fnp-3326	428	17	αsyn	αsyn	NOUN
fnp-3326	428	18	into	into	ADP
fnp-3326	428	19	the	the	DET
fnp-3326	428	20	vagal	vagal	ADJ
fnp-3326	428	21	nerve	nerve	NOUN
fnp-3326	428	22	suggest	suggest	VERB
fnp-3326	428	23	that	that	SCONJ
fnp-3326	428	24	pathogenic	pathogenic	ADJ
fnp-3326	428	25	seeds	seed	NOUN
fnp-3326	428	26	can	can	AUX
fnp-3326	428	27	be	be	AUX
fnp-3326	428	28	transmitted	transmit	VERB
fnp-3326	428	29	via	via	ADP
fnp-3326	428	30	the	the	DET
fnp-3326	428	31	vagal	vagal	ADJ
fnp-3326	428	32	nerve	nerve	NOUN
fnp-3326	429	1	[	[	X
fnp-3326	429	2	15,19,20,64,67,90–92	15,19,20,64,67,90–92	NUM
fnp-3326	429	3	]	]	X
fnp-3326	429	4	.	.	PUNCT
fnp-3326	430	1	a	a	DET
fnp-3326	430	2	role	role	NOUN
fnp-3326	430	3	for	for	ADP
fnp-3326	430	4	the	the	DET
fnp-3326	430	5	vagal	vagal	ADJ
fnp-3326	430	6	nerve	nerve	NOUN
fnp-3326	430	7	in	in	ADP
fnp-3326	430	8	pd	pd	PROPN
fnp-3326	430	9	was	be	AUX
fnp-3326	430	10	also	also	ADV
fnp-3326	430	11	suggested	suggest	VERB
fnp-3326	430	12	by	by	ADP
fnp-3326	430	13	an	an	DET
fnp-3326	430	14	epidemiological	epidemiological	ADJ
fnp-3326	430	15	study	study	NOUN
fnp-3326	430	16	indicating	indicate	VERB
fnp-3326	430	17	that	that	SCONJ
fnp-3326	430	18	vagotomy	vagotomy	NOUN
fnp-3326	430	19	in	in	ADP
fnp-3326	430	20	a	a	DET
fnp-3326	430	21	danish	danish	ADJ
fnp-3326	430	22	population	population	NOUN
fnp-3326	430	23	is	be	AUX
fnp-3326	430	24	associated	associate	VERB
fnp-3326	430	25	with	with	ADP
fnp-3326	430	26	decreased	decrease	VERB
fnp-3326	430	27	pd	pd	PROPN
fnp-3326	430	28	risk	risk	NOUN
fnp-3326	430	29	[	[	X
fnp-3326	430	30	93	93	NUM
fnp-3326	430	31	]	]	PUNCT
fnp-3326	430	32	,	,	PUNCT
fnp-3326	430	33	although	although	SCONJ
fnp-3326	430	34	this	this	DET
fnp-3326	430	35	association	association	NOUN
fnp-3326	430	36	has	have	AUX
fnp-3326	430	37	been	be	AUX
fnp-3326	430	38	challenged	challenge	VERB
fnp-3326	430	39	[	[	X
fnp-3326	430	40	94	94	NUM
fnp-3326	430	41	]	]	PUNCT
fnp-3326	430	42	.	.	PUNCT
fnp-3326	431	1	in	in	ADP
fnp-3326	431	2	the	the	DET
fnp-3326	431	3	present	present	ADJ
fnp-3326	431	4	study	study	NOUN
fnp-3326	431	5	,	,	PUNCT
fnp-3326	431	6	αsyn	αsyn	PROPN
fnp-3326	431	7	pathology	pathology	NOUN
fnp-3326	431	8	was	be	AUX
fnp-3326	431	9	much	much	ADV
fnp-3326	431	10	more	more	ADV
fnp-3326	431	11	prominent	prominent	ADJ
fnp-3326	431	12	in	in	ADP
fnp-3326	431	13	the	the	DET
fnp-3326	431	14	reticular	reticular	ADJ
fnp-3326	431	15	nucleus	nucleus	NOUN
fnp-3326	431	16	(	(	PUNCT
fnp-3326	431	17	including	include	VERB
fnp-3326	431	18	the	the	DET
fnp-3326	431	19	vagal	vagal	ADJ
fnp-3326	431	20	nucleus	nucleus	NOUN
fnp-3326	431	21	)	)	PUNCT
fnp-3326	431	22	and	and	CCONJ
fnp-3326	431	23	midbrain	midbrain	NOUN
fnp-3326	431	24	areas	area	NOUN
fnp-3326	431	25	compared	compare	VERB
fnp-3326	431	26	to	to	ADP
fnp-3326	431	27	the	the	DET
fnp-3326	431	28	rostral	rostral	ADJ
fnp-3326	431	29	areas	area	NOUN
fnp-3326	431	30	at	at	ADP
fnp-3326	431	31	18	18	NUM
fnp-3326	431	32	months	month	NOUN
fnp-3326	431	33	post	post	NOUN
fnp-3326	431	34	dss	dss	NOUN
fnp-3326	431	35	colitis	colitis	NOUN
fnp-3326	431	36	.	.	PUNCT
fnp-3326	432	1	although	although	SCONJ
fnp-3326	432	2	we	we	PRON
fnp-3326	432	3	did	do	AUX
fnp-3326	432	4	not	not	PART
fnp-3326	432	5	conduct	conduct	VERB
fnp-3326	432	6	the	the	DET
fnp-3326	432	7	definitive	definitive	ADJ
fnp-3326	432	8	experiment	experiment	NOUN
fnp-3326	432	9	of	of	ADP
fnp-3326	432	10	cutting	cut	VERB
fnp-3326	432	11	the	the	DET
fnp-3326	432	12	vagal	vagal	ADJ
fnp-3326	432	13	nerve	nerve	NOUN
fnp-3326	432	14	,	,	PUNCT
fnp-3326	432	15	our	our	PRON
fnp-3326	432	16	data	datum	NOUN
fnp-3326	432	17	are	be	AUX
fnp-3326	432	18	consistent	consistent	ADJ
fnp-3326	432	19	with	with	ADP
fnp-3326	432	20	the	the	DET
fnp-3326	432	21	growing	grow	VERB
fnp-3326	432	22	body	body	NOUN
fnp-3326	432	23	of	of	ADP
fnp-3326	432	24	evidence	evidence	NOUN
fnp-3326	432	25	that	that	SCONJ
fnp-3326	432	26	the	the	DET
fnp-3326	432	27	vagal	vagal	ADJ
fnp-3326	432	28	nerve	nerve	NOUN
fnp-3326	432	29	is	be	AUX
fnp-3326	432	30	involved	involve	VERB
fnp-3326	432	31	in	in	ADP
fnp-3326	432	32	the	the	DET
fnp-3326	432	33	accumulation	accumulation	NOUN
fnp-3326	432	34	of	of	ADP
fnp-3326	432	35	αsyn	αsyn	ADJ
fnp-3326	432	36	aggregates	aggregate	NOUN
fnp-3326	432	37	in	in	ADP
fnp-3326	432	38	the	the	DET
fnp-3326	432	39	brain	brain	NOUN
fnp-3326	432	40	.	.	PUNCT
fnp-3326	433	1	that	that	PRON
fnp-3326	433	2	said	say	VERB
fnp-3326	433	3	,	,	PUNCT
fnp-3326	433	4	the	the	DET
fnp-3326	433	5	innervation	innervation	NOUN
fnp-3326	433	6	of	of	ADP
fnp-3326	433	7	the	the	DET
fnp-3326	433	8	colon	colon	NOUN
fnp-3326	433	9	occurs	occur	VERB
fnp-3326	433	10	via	via	ADP
fnp-3326	433	11	both	both	CCONJ
fnp-3326	433	12	parasympathetic	parasympathetic	ADJ
fnp-3326	433	13	(	(	PUNCT
fnp-3326	433	14	e.g.	e.g.	ADV
fnp-3326	433	15	,	,	PUNCT
fnp-3326	433	16	vagal	vagal	ADJ
fnp-3326	433	17	output	output	NOUN
fnp-3326	433	18	neurons	neuron	NOUN
fnp-3326	433	19	)	)	PUNCT
fnp-3326	433	20	and	and	CCONJ
fnp-3326	433	21	sympathetic	sympathetic	ADJ
fnp-3326	433	22	(	(	PUNCT
fnp-3326	433	23	e.g.	e.g.	ADV
fnp-3326	433	24	,	,	PUNCT
fnp-3326	433	25	in	in	ADP
fnp-3326	433	26	the	the	DET
fnp-3326	433	27	celiac	celiac	ADJ
fnp-3326	433	28	ganglion	ganglion	NOUN
fnp-3326	433	29	of	of	ADP
fnp-3326	433	30	the	the	DET
fnp-3326	433	31	upper	upper	ADJ
fnp-3326	433	32	abdomen	abdomen	NOUN
fnp-3326	433	33	)	)	PUNCT
fnp-3326	433	34	nerves	nerve	NOUN
fnp-3326	433	35	.	.	PUNCT
fnp-3326	434	1	the	the	DET
fnp-3326	434	2	possibility	possibility	NOUN
fnp-3326	434	3	of	of	ADP
fnp-3326	434	4	propagation	propagation	NOUN
fnp-3326	434	5	of	of	ADP
fnp-3326	434	6	αsyn	αsyn	ADJ
fnp-3326	434	7	pathology	pathology	NOUN
fnp-3326	434	8	via	via	ADP
fnp-3326	434	9	the	the	DET
fnp-3326	434	10	two	two	NUM
fnp-3326	434	11	routes	route	NOUN
fnp-3326	434	12	is	be	AUX
fnp-3326	434	13	supported	support	VERB
fnp-3326	434	14	by	by	ADP
fnp-3326	434	15	the	the	DET
fnp-3326	434	16	observation	observation	NOUN
fnp-3326	434	17	that	that	SCONJ
fnp-3326	434	18	injection	injection	NOUN
fnp-3326	434	19	of	of	ADP
fnp-3326	434	20	recombinant	recombinant	ADJ
fnp-3326	434	21	αsyn	αsyn	NOUN
fnp-3326	434	22	fibrils	fibril	NOUN
fnp-3326	434	23	to	to	ADP
fnp-3326	434	24	the	the	DET
fnp-3326	434	25	duodenum	duodenum	NOUN
fnp-3326	434	26	of	of	ADP
fnp-3326	434	27	certain	certain	ADJ
fnp-3326	434	28	αsyn	αsyn	ADJ
fnp-3326	434	29	transgenic	transgenic	NOUN
fnp-3326	434	30	rats	rat	NOUN
fnp-3326	434	31	leads	lead	VERB
fnp-3326	434	32	to	to	ADP
fnp-3326	434	33	accumulation	accumulation	NOUN
fnp-3326	434	34	of	of	ADP
fnp-3326	434	35	pathological	pathological	ADJ
fnp-3326	434	36	αsyn	αsyn	NOUN
fnp-3326	434	37	in	in	ADP
fnp-3326	434	38	organs	organ	NOUN
fnp-3326	434	39	innervated	innervate	VERB
fnp-3326	434	40	by	by	ADP
fnp-3326	434	41	the	the	DET
fnp-3326	434	42	parasympathetic	parasympathetic	NOUN
fnp-3326	434	43	and	and	CCONJ
fnp-3326	434	44	the	the	DET
fnp-3326	434	45	sympathetic	sympathetic	ADJ
fnp-3326	434	46	nerves	nerve	NOUN
fnp-3326	434	47	[	[	X
fnp-3326	434	48	67	67	NUM
fnp-3326	434	49	]	]	PUNCT
fnp-3326	434	50	and	and	CCONJ
fnp-3326	434	51	an	an	DET
fnp-3326	434	52	age	age	NOUN
fnp-3326	434	53	-	-	PUNCT
fnp-3326	434	54	dependent	dependent	ADJ
fnp-3326	434	55	propagation	propagation	NOUN
fnp-3326	434	56	of	of	ADP
fnp-3326	434	57	αsyn	αsyn	ADJ
fnp-3326	434	58	pathology	pathology	NOUN
fnp-3326	434	59	from	from	ADP
fnp-3326	434	60	gut	gut	NOUN
fnp-3326	434	61	-	-	PUNCT
fnp-3326	434	62	to	to	ADP
fnp-3326	434	63	-	-	PUNCT
fnp-3326	434	64	brain	brain	NOUN
fnp-3326	434	65	in	in	ADP
fnp-3326	434	66	wild	wild	ADJ
fnp-3326	434	67	type	type	NOUN
fnp-3326	434	68	rats	rat	NOUN
fnp-3326	434	69	[	[	X
fnp-3326	434	70	64	64	NUM
fnp-3326	434	71	]	]	PUNCT
fnp-3326	434	72	.	.	PUNCT
fnp-3326	435	1	clinically	clinically	ADV
fnp-3326	435	2	,	,	PUNCT
fnp-3326	435	3	more	more	ADV
fnp-3326	435	4	relevant	relevant	ADJ
fnp-3326	435	5	,	,	PUNCT
fnp-3326	435	6	αsyn	αsyn	ADJ
fnp-3326	435	7	accumulation	accumulation	NOUN
fnp-3326	435	8	is	be	AUX
fnp-3326	435	9	present	present	ADJ
fnp-3326	435	10	in	in	ADP
fnp-3326	435	11	both	both	CCONJ
fnp-3326	435	12	parasympathetic	parasympathetic	ADJ
fnp-3326	435	13	and	and	CCONJ
fnp-3326	435	14	sympathetic	sympathetic	ADJ
fnp-3326	435	15	vagal	vagal	ADJ
fnp-3326	435	16	nerves	nerve	NOUN
fnp-3326	435	17	in	in	ADP
fnp-3326	435	18	humans	human	NOUN
fnp-3326	435	19	as	as	ADV
fnp-3326	435	20	well	well	ADV
fnp-3326	435	21	[	[	X
fnp-3326	435	22	95	95	NUM
fnp-3326	435	23	]	]	PUNCT
fnp-3326	435	24	.	.	PUNCT
fnp-3326	436	1	thus	thus	ADV
fnp-3326	436	2	,	,	PUNCT
fnp-3326	436	3	propagation	propagation	NOUN
fnp-3326	436	4	may	may	AUX
fnp-3326	436	5	occur	occur	VERB
fnp-3326	436	6	through	through	ADP
fnp-3326	436	7	both	both	CCONJ
fnp-3326	436	8	vagal	vagal	ADJ
fnp-3326	436	9	and	and	CCONJ
fnp-3326	436	10	spinal	spinal	ADJ
fnp-3326	436	11	routes	route	NOUN
fnp-3326	436	12	.	.	PUNCT
fnp-3326	437	1	aging	aging	NOUN
fnp-3326	437	2	is	be	AUX
fnp-3326	437	3	considered	consider	VERB
fnp-3326	437	4	a	a	DET
fnp-3326	437	5	major	major	ADJ
fnp-3326	437	6	risk	risk	NOUN
fnp-3326	437	7	factor	factor	NOUN
fnp-3326	437	8	for	for	ADP
fnp-3326	437	9	neurodegenerative	neurodegenerative	ADJ
fnp-3326	437	10	diseases	disease	NOUN
fnp-3326	437	11	,	,	PUNCT
fnp-3326	437	12	as	as	SCONJ
fnp-3326	437	13	failing	fail	VERB
fnp-3326	437	14	cellular	cellular	ADJ
fnp-3326	437	15	mechanisms	mechanism	NOUN
fnp-3326	437	16	are	be	AUX
fnp-3326	437	17	proposed	propose	VERB
fnp-3326	437	18	to	to	PART
fnp-3326	437	19	be	be	AUX
fnp-3326	437	20	unable	unable	ADJ
fnp-3326	437	21	to	to	PART
fnp-3326	437	22	efficiently	efficiently	ADV
fnp-3326	437	23	clear	clear	VERB
fnp-3326	437	24	pathologically	pathologically	ADV
fnp-3326	437	25	accumulating	accumulate	VERB
fnp-3326	437	26	proteins	protein	NOUN
fnp-3326	437	27	and	and	CCONJ
fnp-3326	437	28	organelles	organelle	NOUN
fnp-3326	438	1	[	[	X
fnp-3326	438	2	96	96	NUM
fnp-3326	438	3	]	]	PUNCT
fnp-3326	438	4	.	.	PUNCT
fnp-3326	439	1	intriguingly	intriguingly	ADV
fnp-3326	439	2	,	,	PUNCT
fnp-3326	439	3	in	in	ADP
fnp-3326	439	4	the	the	DET
fnp-3326	439	5	current	current	ADJ
fnp-3326	439	6	study	study	NOUN
fnp-3326	439	7	,	,	PUNCT
fnp-3326	439	8	while	while	SCONJ
fnp-3326	439	9	both	both	DET
fnp-3326	439	10	cohorts	cohort	NOUN
fnp-3326	439	11	were	be	AUX
fnp-3326	439	12	exposed	expose	VERB
fnp-3326	439	13	to	to	ADP
fnp-3326	439	14	the	the	DET
fnp-3326	439	15	same	same	ADJ
fnp-3326	439	16	peripheral	peripheral	ADJ
fnp-3326	439	17	dss	dss	NOUN
fnp-3326	439	18	colitis	colitis	NOUN
fnp-3326	439	19	insult	insult	NOUN
fnp-3326	439	20	at	at	ADP
fnp-3326	439	21	3	3	NUM
fnp-3326	439	22	months	month	NOUN
fnp-3326	439	23	of	of	ADP
fnp-3326	439	24	age	age	NOUN
fnp-3326	439	25	,	,	PUNCT
fnp-3326	439	26	αsyn	αsyn	ADJ
fnp-3326	439	27	pathology	pathology	NOUN
fnp-3326	439	28	only	only	ADV
fnp-3326	439	29	developed	develop	VERB
fnp-3326	439	30	in	in	ADP
fnp-3326	439	31	the	the	DET
fnp-3326	439	32	brain	brain	NOUN
fnp-3326	439	33	of	of	ADP
fnp-3326	439	34	aged	aged	ADJ
fnp-3326	439	35	(	(	PUNCT
fnp-3326	439	36	21	21	NUM
fnp-3326	439	37	-	-	PUNCT
fnp-3326	439	38	month	month	NOUN
fnp-3326	439	39	-	-	PUNCT
fnp-3326	439	40	old	old	ADJ
fnp-3326	439	41	)	)	PUNCT
fnp-3326	439	42	but	but	CCONJ
fnp-3326	439	43	not	not	PART
fnp-3326	439	44	in	in	ADP
fnp-3326	439	45	the	the	DET
fnp-3326	439	46	relatively	relatively	ADV
fnp-3326	439	47	younger	young	ADJ
fnp-3326	439	48	(	(	PUNCT
fnp-3326	439	49	9	9	NUM
fnp-3326	439	50	-	-	PUNCT
fnp-3326	439	51	month	month	NOUN
fnp-3326	439	52	-	-	PUNCT
fnp-3326	439	53	old	old	ADJ
fnp-3326	439	54	)	)	PUNCT
fnp-3326	439	55	mice	mouse	NOUN
fnp-3326	439	56	(	(	PUNCT
fnp-3326	439	57	fig	fig	NOUN
fnp-3326	439	58	.	.	PUNCT
fnp-3326	440	1	5	5	NUM
fnp-3326	440	2	)	)	PUNCT
fnp-3326	441	1	.	.	PUNCT
fnp-3326	442	1	while	while	SCONJ
fnp-3326	442	2	the	the	DET
fnp-3326	442	3	mechanisms	mechanism	NOUN
fnp-3326	442	4	involved	involve	VERB
fnp-3326	442	5	in	in	ADP
fnp-3326	442	6	this	this	DET
fnp-3326	442	7	phenomenon	phenomenon	NOUN
fnp-3326	442	8	are	be	AUX
fnp-3326	442	9	still	still	ADV
fnp-3326	442	10	unclear	unclear	ADJ
fnp-3326	442	11	,	,	PUNCT
fnp-3326	442	12	a	a	DET
fnp-3326	442	13	recent	recent	ADJ
fnp-3326	442	14	study	study	NOUN
fnp-3326	442	15	in	in	ADP
fnp-3326	442	16	mice	mice	NOUN
fnp-3326	442	17	reports	report	NOUN
fnp-3326	442	18	an	an	DET
fnp-3326	442	19	age	age	NOUN
fnp-3326	442	20	-	-	PUNCT
fnp-3326	442	21	dependent	dependent	ADJ
fnp-3326	442	22	association	association	NOUN
fnp-3326	442	23	of	of	ADP
fnp-3326	442	24	development	development	NOUN
fnp-3326	442	25	of	of	ADP
fnp-3326	442	26	αsyn	αsyn	ADJ
fnp-3326	442	27	pathology	pathology	NOUN
fnp-3326	442	28	in	in	ADP
fnp-3326	442	29	the	the	DET
fnp-3326	442	30	brain	brain	NOUN
fnp-3326	442	31	and	and	CCONJ
fnp-3326	442	32	development	development	NOUN
fnp-3326	442	33	of	of	ADP
fnp-3326	442	34	motor	motor	NOUN
fnp-3326	442	35	deficits	deficit	NOUN
fnp-3326	442	36	after	after	ADP
fnp-3326	442	37	inoculating	inoculate	VERB
fnp-3326	442	38	the	the	DET
fnp-3326	442	39	gut	gut	NOUN
fnp-3326	442	40	wall	wall	NOUN
fnp-3326	442	41	with	with	ADP
fnp-3326	442	42	recombinant	recombinant	ADJ
fnp-3326	442	43	αsyn	αsyn	NOUN
fnp-3326	442	44	fibrils	fibril	NOUN
fnp-3326	442	45	[	[	X
fnp-3326	442	46	20	20	NUM
fnp-3326	442	47	]	]	PUNCT
fnp-3326	442	48	.	.	PUNCT
fnp-3326	443	1	investigating	investigate	VERB
fnp-3326	443	2	this	this	PRON
fnp-3326	443	3	further	far	ADV
fnp-3326	443	4	,	,	PUNCT
fnp-3326	443	5	the	the	DET
fnp-3326	443	6	study	study	NOUN
fnp-3326	443	7	observed	observe	VERB
fnp-3326	443	8	a	a	DET
fnp-3326	443	9	reduction	reduction	NOUN
fnp-3326	443	10	of	of	ADP
fnp-3326	443	11	the	the	DET
fnp-3326	443	12	lysosomal	lysosomal	ADJ
fnp-3326	443	13	enzyme	enzyme	NOUN
fnp-3326	443	14	glucocerebrosidase	glucocerebrosidase	NOUN
fnp-3326	443	15	in	in	ADP
fnp-3326	443	16	the	the	DET
fnp-3326	443	17	gut	gut	NOUN
fnp-3326	443	18	of	of	ADP
fnp-3326	443	19	aged	aged	ADJ
fnp-3326	443	20	but	but	CCONJ
fnp-3326	443	21	not	not	PART
fnp-3326	443	22	young	young	ADJ
fnp-3326	443	23	mice	mouse	NOUN
fnp-3326	443	24	[	[	X
fnp-3326	443	25	20	20	NUM
fnp-3326	443	26	]	]	PUNCT
fnp-3326	443	27	.	.	PUNCT
fnp-3326	444	1	viral	viral	ADJ
fnp-3326	444	2	vector	vector	NOUN
fnp-3326	444	3	-	-	PUNCT
fnp-3326	444	4	based	base	VERB
fnp-3326	444	5	overexpression	overexpression	NOUN
fnp-3326	444	6	of	of	ADP
fnp-3326	444	7	glucocerebrosidase	glucocerebrosidase	NOUN
fnp-3326	444	8	partially	partially	ADV
fnp-3326	444	9	rescued	rescue	VERB
fnp-3326	444	10	the	the	DET
fnp-3326	444	11	ens	ens	PROPN
fnp-3326	444	12	network	network	NOUN
fnp-3326	444	13	connectivity	connectivity	NOUN
fnp-3326	444	14	with	with	ADP
fnp-3326	444	15	concomitant	concomitant	ADJ
fnp-3326	444	16	variable	variable	ADJ
fnp-3326	444	17	downregulation	downregulation	NOUN
fnp-3326	444	18	of	of	ADP
fnp-3326	444	19	pser129	pser129	ADJ
fnp-3326	444	20	-	-	PUNCT
fnp-3326	444	21	αsyn	αsyn	ADJ
fnp-3326	444	22	levels	level	NOUN
fnp-3326	444	23	[	[	X
fnp-3326	444	24	20	20	NUM
fnp-3326	444	25	]	]	PUNCT
fnp-3326	444	26	.	.	PUNCT
fnp-3326	445	1	although	although	SCONJ
fnp-3326	445	2	other	other	ADJ
fnp-3326	445	3	age	age	NOUN
fnp-3326	445	4	-	-	PUNCT
fnp-3326	445	5	related	relate	VERB
fnp-3326	445	6	factors	factor	NOUN
fnp-3326	445	7	are	be	AUX
fnp-3326	445	8	likely	likely	ADV
fnp-3326	445	9	involved	involve	VERB
fnp-3326	445	10	,	,	PUNCT
fnp-3326	445	11	the	the	DET
fnp-3326	445	12	finding	finding	NOUN
fnp-3326	445	13	of	of	ADP
fnp-3326	445	14	challis	challi	NOUN
fnp-3326	445	15	and	and	CCONJ
fnp-3326	445	16	colleagues	colleague	NOUN
fnp-3326	445	17	,	,	PUNCT
fnp-3326	445	18	together	together	ADV
fnp-3326	445	19	with	with	ADP
fnp-3326	445	20	the	the	DET
fnp-3326	445	21	well	well	ADV
fnp-3326	445	22	-	-	PUNCT
fnp-3326	445	23	known	know	VERB
fnp-3326	445	24	genetic	genetic	ADJ
fnp-3326	445	25	risk	risk	NOUN
fnp-3326	445	26	for	for	ADP
fnp-3326	445	27	glucocerebrosidase	glucocerebrosidase	NOUN
fnp-3326	445	28	and	and	CCONJ
fnp-3326	445	29	several	several	ADJ
fnp-3326	445	30	other	other	ADJ
fnp-3326	445	31	lysosomal	lysosomal	ADJ
fnp-3326	445	32	genes	gene	NOUN
fnp-3326	445	33	in	in	ADP
fnp-3326	445	34	pd	pd	PROPN
fnp-3326	445	35	[	[	X
fnp-3326	445	36	97,98	97,98	NOUN
fnp-3326	445	37	]	]	PUNCT
fnp-3326	445	38	,	,	PUNCT
fnp-3326	445	39	suggest	suggest	VERB
fnp-3326	445	40	a	a	DET
fnp-3326	445	41	critical	critical	ADJ
fnp-3326	445	42	role	role	NOUN
fnp-3326	445	43	of	of	ADP
fnp-3326	445	44	the	the	DET
fnp-3326	445	45	lysosomal	lysosomal	ADJ
fnp-3326	445	46	pathway	pathway	NOUN
fnp-3326	445	47	in	in	ADP
fnp-3326	445	48	the	the	DET
fnp-3326	445	49	long	long	ADJ
fnp-3326	445	50	-	-	PUNCT
fnp-3326	445	51	term	term	NOUN
fnp-3326	445	52	persistence	persistence	NOUN
fnp-3326	445	53	of	of	ADP
fnp-3326	445	54	pathology	pathology	NOUN
fnp-3326	445	55	in	in	ADP
fnp-3326	445	56	the	the	DET
fnp-3326	445	57	ens	ens	NOUN
fnp-3326	445	58	and	and	CCONJ
fnp-3326	445	59	the	the	DET
fnp-3326	445	60	progression	progression	NOUN
fnp-3326	445	61	of	of	ADP
fnp-3326	445	62	αsyn	αsyn	ADJ
fnp-3326	445	63	pathology	pathology	NOUN
fnp-3326	445	64	from	from	ADP
fnp-3326	445	65	the	the	DET
fnp-3326	445	66	gut	gut	NOUN
fnp-3326	445	67	to	to	ADP
fnp-3326	445	68	the	the	DET
fnp-3326	445	69	brain	brain	NOUN
fnp-3326	445	70	of	of	ADP
fnp-3326	445	71	aged	aged	ADJ
fnp-3326	445	72	mice	mouse	NOUN
fnp-3326	445	73	.	.	PUNCT
fnp-3326	446	1	upcoming	upcoming	ADJ
fnp-3326	446	2	studies	study	NOUN
fnp-3326	446	3	in	in	ADP
fnp-3326	446	4	human	human	ADJ
fnp-3326	446	5	tissue	tissue	NOUN
fnp-3326	446	6	may	may	AUX
fnp-3326	446	7	shed	shed	VERB
fnp-3326	446	8	more	more	ADJ
fnp-3326	446	9	light	light	NOUN
fnp-3326	446	10	on	on	ADP
fnp-3326	446	11	the	the	DET
fnp-3326	446	12	mechanisms	mechanism	NOUN
fnp-3326	446	13	on	on	ADP
fnp-3326	446	14	how	how	SCONJ
fnp-3326	446	15	autophagy	autophagy	ADJ
fnp-3326	446	16	-	-	PUNCT
fnp-3326	446	17	lysosomal	lysosomal	ADJ
fnp-3326	446	18	pathways	pathway	NOUN
fnp-3326	446	19	are	be	AUX
fnp-3326	446	20	regulated	regulate	VERB
fnp-3326	446	21	and	and	CCONJ
fnp-3326	446	22	how	how	SCONJ
fnp-3326	446	23	they	they	PRON
fnp-3326	446	24	,	,	PUNCT
fnp-3326	446	25	together	together	ADV
fnp-3326	446	26	with	with	ADP
fnp-3326	446	27	aging	aging	NOUN
fnp-3326	446	28	,	,	PUNCT
fnp-3326	446	29	may	may	AUX
fnp-3326	446	30	contribute	contribute	VERB
fnp-3326	446	31	to	to	ADP
fnp-3326	446	32	the	the	DET
fnp-3326	446	33	pathogenesis	pathogenesis	NOUN
fnp-3326	446	34	in	in	ADP
fnp-3326	446	35	pd	pd	PROPN
fnp-3326	446	36	.	.	PUNCT
fnp-3326	447	1	in	in	ADP
fnp-3326	447	2	summary	summary	NOUN
fnp-3326	447	3	,	,	PUNCT
fnp-3326	447	4	we	we	PRON
fnp-3326	447	5	report	report	VERB
fnp-3326	447	6	that	that	SCONJ
fnp-3326	447	7	αsyn	αsyn	PROPN
fnp-3326	447	8	accumulates	accumulate	VERB
fnp-3326	447	9	in	in	ADP
fnp-3326	447	10	the	the	DET
fnp-3326	447	11	colon	colon	NOUN
fnp-3326	447	12	of	of	ADP
fnp-3326	447	13	αsyn	αsyn	ADJ
fnp-3326	447	14	transgenic	transgenic	NOUN
fnp-3326	447	15	and	and	CCONJ
fnp-3326	447	16	wild	wild	ADJ
fnp-3326	447	17	type	type	NOUN
fnp-3326	447	18	mice	mouse	NOUN
fnp-3326	447	19	subjected	subject	VERB
fnp-3326	447	20	to	to	ADP
fnp-3326	447	21	experimental	experimental	ADJ
fnp-3326	447	22	dss	dss	NOUN
fnp-3326	447	23	colitis	colitis	NOUN
fnp-3326	447	24	and	and	CCONJ
fnp-3326	447	25	that	that	SCONJ
fnp-3326	447	26	this	this	DET
fnp-3326	447	27	process	process	NOUN
fnp-3326	447	28	can	can	AUX
fnp-3326	447	29	be	be	AUX
fnp-3326	447	30	modulated	modulate	VERB
fnp-3326	447	31	by	by	ADP
fnp-3326	447	32	genetically	genetically	ADV
fnp-3326	447	33	and	and	CCONJ
fnp-3326	447	34	pharmacologically	pharmacologically	ADV
fnp-3326	447	35	modifying	modify	VERB
fnp-3326	447	36	pathways	pathway	NOUN
fnp-3326	447	37	related	relate	VERB
fnp-3326	447	38	to	to	ADP
fnp-3326	447	39	monocyte	monocyte	NOUN
fnp-3326	447	40	/	/	SYM
fnp-3326	447	41	macrophage	macrophage	ADJ
fnp-3326	447	42	signaling	signaling	NOUN
fnp-3326	447	43	.	.	PUNCT
fnp-3326	448	1	we	we	PRON
fnp-3326	448	2	further	far	ADV
fnp-3326	448	3	demonstrate	demonstrate	VERB
fnp-3326	448	4	that	that	SCONJ
fnp-3326	448	5	chronic	chronic	NOUN
fnp-3326	448	6	but	but	CCONJ
fnp-3326	448	7	transient	transient	ADJ
fnp-3326	448	8	dss	dss	NOUN
fnp-3326	448	9	colitis	colitis	NOUN
fnp-3326	448	10	in	in	ADP
fnp-3326	448	11	young	young	ADJ
fnp-3326	448	12	αsyn	αsyn	ADJ
fnp-3326	448	13	transgenic	transgenic	NOUN
fnp-3326	448	14	mice	mouse	NOUN
fnp-3326	448	15	leads	lead	VERB
fnp-3326	448	16	to	to	ADP
fnp-3326	448	17	a	a	DET
fnp-3326	448	18	markedly	markedly	ADV
fnp-3326	448	19	exacerbated	exacerbate	VERB
fnp-3326	448	20	accumulation	accumulation	NOUN
fnp-3326	448	21	of	of	ADP
fnp-3326	448	22	αsyn	αsyn	ADJ
fnp-3326	448	23	aggregates	aggregate	NOUN
fnp-3326	448	24	in	in	ADP
fnp-3326	448	25	the	the	DET
fnp-3326	448	26	brain	brain	NOUN
fnp-3326	448	27	of	of	ADP
fnp-3326	448	28	aged	aged	ADJ
fnp-3326	448	29	mice	mouse	NOUN
fnp-3326	448	30	.	.	PUNCT
fnp-3326	449	1	in	in	ADP
fnp-3326	449	2	the	the	DET
fnp-3326	449	3	same	same	ADJ
fnp-3326	449	4	aged	aged	ADJ
fnp-3326	449	5	mice	mouse	NOUN
fnp-3326	449	6	,	,	PUNCT
fnp-3326	449	7	the	the	DET
fnp-3326	449	8	numbers	number	NOUN
fnp-3326	449	9	of	of	ADP
fnp-3326	449	10	thand	thand	PROPN
fnp-3326	449	11	nissl	nissl	ADJ
fnp-3326	449	12	-	-	PUNCT
fnp-3326	449	13	positive	positive	ADJ
fnp-3326	449	14	neurons	neuron	NOUN
fnp-3326	449	15	in	in	ADP
fnp-3326	449	16	the	the	DET
fnp-3326	449	17	substantia	substantia	NOUN
fnp-3326	449	18	nigra	nigra	NOUN
fnp-3326	449	19	are	be	AUX
fnp-3326	449	20	reduced	reduce	VERB
fnp-3326	449	21	,	,	PUNCT
fnp-3326	449	22	suggestive	suggestive	ADJ
fnp-3326	449	23	of	of	ADP
fnp-3326	449	24	a	a	DET
fnp-3326	449	25	neurodegenerative	neurodegenerative	ADJ
fnp-3326	449	26	process	process	NOUN
fnp-3326	449	27	.	.	PUNCT
fnp-3326	450	1	together	together	ADV
fnp-3326	450	2	,	,	PUNCT
fnp-3326	450	3	our	our	PRON
fnp-3326	450	4	findings	finding	NOUN
fnp-3326	450	5	are	be	AUX
fnp-3326	450	6	in	in	ADP
fnp-3326	450	7	consonance	consonance	NOUN
fnp-3326	450	8	with	with	ADP
fnp-3326	450	9	studies	study	NOUN
fnp-3326	450	10	demonstrating	demonstrate	VERB
fnp-3326	450	11	a	a	DET
fnp-3326	450	12	link	link	NOUN
fnp-3326	450	13	between	between	ADP
fnp-3326	450	14	ibd	ibd	PROPN
fnp-3326	450	15	and	and	CCONJ
fnp-3326	450	16	pd	pd	NOUN
fnp-3326	451	1	[	[	X
fnp-3326	451	2	33,35,99	33,35,99	NUM
fnp-3326	451	3	]	]	PUNCT
fnp-3326	451	4	and	and	CCONJ
fnp-3326	451	5	suggest	suggest	VERB
fnp-3326	451	6	a	a	DET
fnp-3326	451	7	critical	critical	ADJ
fnp-3326	451	8	role	role	NOUN
fnp-3326	451	9	for	for	ADP
fnp-3326	451	10	specific	specific	ADJ
fnp-3326	451	11	types	type	NOUN
fnp-3326	451	12	of	of	ADP
fnp-3326	451	13	intestinal	intestinal	ADJ
fnp-3326	451	14	inflammation	inflammation	NOUN
fnp-3326	451	15	and	and	CCONJ
fnp-3326	451	16	αsyn	αsyn	ADJ
fnp-3326	451	17	accumulation	accumulation	NOUN
fnp-3326	451	18	in	in	ADP
fnp-3326	451	19	the	the	DET
fnp-3326	451	20	initiation	initiation	NOUN
fnp-3326	451	21	and	and	CCONJ
fnp-3326	451	22	progression	progression	NOUN
fnp-3326	451	23	of	of	ADP
fnp-3326	451	24	pd	pd	PROPN
fnp-3326	451	25	.	.	PUNCT
fnp-3326	451	26	acknowledgments	acknowledgment	NOUN
fnp-3326	451	27	including	include	VERB
fnp-3326	451	28	sources	source	NOUN
fnp-3326	451	29	of	of	ADP
fnp-3326	451	30	support	support	NOUN
fnp-3326	451	31	we	we	PRON
fnp-3326	451	32	thank	thank	VERB
fnp-3326	451	33	drs	drs	PROPN
fnp-3326	451	34	.	.	PUNCT
fnp-3326	452	1	l.	l.	PROPN
fnp-3326	452	2	ozmen	ozmen	PROPN
fnp-3326	452	3	and	and	CCONJ
fnp-3326	452	4	a.	a.	NOUN
fnp-3326	452	5	bergadano	bergadano	VERB
fnp-3326	452	6	for	for	ADP
fnp-3326	452	7	their	their	PRON
fnp-3326	452	8	tremendous	tremendous	ADJ
fnp-3326	452	9	support	support	NOUN
fnp-3326	452	10	in	in	ADP
fnp-3326	452	11	maintaining	maintain	VERB
fnp-3326	452	12	the	the	DET
fnp-3326	452	13	mouse	mouse	NOUN
fnp-3326	452	14	colony	colony	NOUN
fnp-3326	452	15	and	and	CCONJ
fnp-3326	452	16	we	we	PRON
fnp-3326	452	17	are	be	AUX
fnp-3326	452	18	grateful	grateful	ADJ
fnp-3326	452	19	to	to	ADP
fnp-3326	452	20	the	the	DET
fnp-3326	452	21	animal	animal	NOUN
fnp-3326	452	22	caretakers	caretaker	NOUN
fnp-3326	452	23	,	,	PUNCT
fnp-3326	452	24	veterinarians	veterinarian	NOUN
fnp-3326	452	25	and	and	CCONJ
fnp-3326	452	26	many	many	ADJ
fnp-3326	452	27	unnamed	unnamed	ADJ
fnp-3326	452	28	staff	staff	NOUN
fnp-3326	452	29	at	at	ADP
fnp-3326	452	30	roche	roche	NOUN
fnp-3326	452	31	for	for	ADP
fnp-3326	452	32	their	their	PRON
fnp-3326	452	33	valuable	valuable	ADJ
fnp-3326	452	34	work	work	NOUN
fnp-3326	452	35	with	with	ADP
fnp-3326	452	36	the	the	DET
fnp-3326	452	37	mice	mouse	NOUN
fnp-3326	452	38	in	in	ADP
fnp-3326	452	39	this	this	DET
fnp-3326	452	40	study	study	NOUN
fnp-3326	452	41	.	.	PUNCT
fnp-3326	453	1	in	in	ADP
fnp-3326	453	2	addition	addition	NOUN
fnp-3326	453	3	,	,	PUNCT
fnp-3326	453	4	at	at	ADP
fnp-3326	453	5	roche	roche	NOUN
fnp-3326	453	6	we	we	PRON
fnp-3326	453	7	thank	thank	VERB
fnp-3326	453	8	dr	dr	PROPN
fnp-3326	453	9	.	.	PROPN
fnp-3326	453	10	k.g	k.g	PROPN
fnp-3326	453	11	.	.	PROPN
fnp-3326	453	12	lassen	lassen	PROPN
fnp-3326	453	13	for	for	ADP
fnp-3326	453	14	critical	critical	ADJ
fnp-3326	453	15	input	input	NOUN
fnp-3326	453	16	to	to	ADP
fnp-3326	453	17	the	the	DET
fnp-3326	453	18	paper	paper	NOUN
fnp-3326	453	19	,	,	PUNCT
fnp-3326	453	20	dr	dr	PROPN
fnp-3326	453	21	.	.	PROPN
fnp-3326	453	22	c.	c.	PROPN
fnp-3326	453	23	ullmer	ullmer	PROPN
fnp-3326	453	24	for	for	ADP
fnp-3326	453	25	co	co	VERB
fnp-3326	453	26	-	-	ADJ
fnp-3326	453	27	mentoring	mentoring	ADJ
fnp-3326	453	28	s.g	s.g	PROPN
fnp-3326	453	29	.	.	PROPN
fnp-3326	453	30	and	and	CCONJ
fnp-3326	453	31	providing	provide	VERB
fnp-3326	453	32	scientific	scientific	ADJ
fnp-3326	453	33	input	input	NOUN
fnp-3326	453	34	,	,	PUNCT
fnp-3326	453	35	dr	dr	PROPN
fnp-3326	453	36	.	.	PROPN
fnp-3326	453	37	l.	l.	PROPN
fnp-3326	453	38	collin	collin	PROPN
fnp-3326	453	39	for	for	ADP
fnp-3326	453	40	helping	help	VERB
fnp-3326	453	41	with	with	ADP
fnp-3326	453	42	confocal	confocal	ADJ
fnp-3326	453	43	imaging	imaging	NOUN
fnp-3326	453	44	and	and	CCONJ
fnp-3326	453	45	we	we	PRON
fnp-3326	453	46	are	be	AUX
fnp-3326	453	47	grateful	grateful	ADJ
fnp-3326	453	48	to	to	ADP
fnp-3326	453	49	dr	dr	PROPN
fnp-3326	453	50	.	.	PROPN
fnp-3326	453	51	t.	t.	PROPN
fnp-3326	453	52	kremer	kremer	PROPN
fnp-3326	453	53	,	,	PUNCT
fnp-3326	453	54	n.	n.	PROPN
fnp-3326	453	55	haenggi	haenggi	PROPN
fnp-3326	453	56	,	,	PUNCT
fnp-3326	453	57	d.	d.	PROPN
fnp-3326	453	58	mona	mona	PROPN
fnp-3326	453	59	,	,	PUNCT
fnp-3326	453	60	a.	a.	PROPN
fnp-3326	453	61	girardeau	girardeau	PROPN
fnp-3326	453	62	,	,	PUNCT
fnp-3326	453	63	and	and	CCONJ
fnp-3326	453	64	j.	j.	PROPN
fnp-3326	453	65	messer	messer	PROPN
fnp-3326	453	66	for	for	ADP
fnp-3326	453	67	providing	provide	VERB
fnp-3326	453	68	support	support	NOUN
fnp-3326	453	69	in	in	ADP
fnp-3326	453	70	tissue	tissue	NOUN
fnp-3326	453	71	dissections	dissection	NOUN
fnp-3326	453	72	and	and	CCONJ
fnp-3326	453	73	g.	g.	PROPN
fnp-3326	453	74	walker	walker	PROPN
fnp-3326	453	75	and	and	CCONJ
fnp-3326	453	76	r.	r.	PROPN
fnp-3326	453	77	lauria	lauria	PROPN
fnp-3326	453	78	for	for	ADP
fnp-3326	453	79	technical	technical	ADJ
fnp-3326	453	80	support	support	NOUN
fnp-3326	453	81	.	.	PUNCT
fnp-3326	454	1	ms	ms	PROPN
fnp-3326	454	2	.	.	PROPN
fnp-3326	454	3	e.	e.	PROPN
fnp-3326	454	4	schulz	schulz	PROPN
fnp-3326	454	5	from	from	ADP
fnp-3326	454	6	vai	vai	PROPN
fnp-3326	454	7	assisted	assist	VERB
fnp-3326	454	8	with	with	ADP
fnp-3326	454	9	immunostaining	immunostaine	VERB
fnp-3326	454	10	of	of	ADP
fnp-3326	454	11	the	the	DET
fnp-3326	454	12	brain	brain	NOUN
fnp-3326	454	13	tissue	tissue	NOUN
fnp-3326	454	14	.	.	PUNCT
fnp-3326	455	1	we	we	PRON
fnp-3326	455	2	thank	thank	VERB
fnp-3326	455	3	the	the	DET
fnp-3326	455	4	contract	contract	NOUN
fnp-3326	455	5	research	research	NOUN
fnp-3326	455	6	organization	organization	NOUN
fnp-3326	455	7	frimorfo	frimorfo	ADJ
fnp-3326	455	8	for	for	ADP
fnp-3326	455	9	carefully	carefully	ADV
fnp-3326	455	10	sectioning	section	VERB
fnp-3326	455	11	the	the	DET
fnp-3326	455	12	brains	brain	NOUN
fnp-3326	455	13	for	for	ADP
fnp-3326	455	14	this	this	DET
fnp-3326	455	15	study	study	NOUN
fnp-3326	455	16	.	.	PUNCT
fnp-3326	456	1	we	we	PRON
fnp-3326	456	2	acknowledge	acknowledge	VERB
fnp-3326	456	3	drs	drs	PROPN
fnp-3326	456	4	.	.	PROPN
fnp-3326	456	5	l.	l.	PROPN
fnp-3326	456	6	gaudimier	gaudimier	PROPN
fnp-3326	456	7	(	(	PUNCT
fnp-3326	456	8	née	née	PROPN
fnp-3326	456	9	chicha	chicha	PROPN
fnp-3326	456	10	)	)	PUNCT
fnp-3326	456	11	and	and	CCONJ
fnp-3326	456	12	f.	f.	PROPN
fnp-3326	456	13	pan	pan	PROPN
fnp-3326	456	14	-	-	PROPN
fnp-3326	456	15	montojo	montojo	NOUN
fnp-3326	456	16	for	for	ADP
fnp-3326	456	17	scientific	scientific	ADJ
fnp-3326	456	18	discussions	discussion	NOUN
fnp-3326	456	19	early	early	ADV
fnp-3326	456	20	in	in	ADP
fnp-3326	456	21	the	the	DET
fnp-3326	456	22	project	project	NOUN
fnp-3326	456	23	,	,	PUNCT
fnp-3326	456	24	dr	dr	PROPN
fnp-3326	456	25	.	.	PROPN
fnp-3326	456	26	w.	w.	PROPN
fnp-3326	456	27	zago	zago	PROPN
fnp-3326	456	28	from	from	ADP
fnp-3326	456	29	prothena	prothena	NOUN
fnp-3326	456	30	for	for	ADP
fnp-3326	456	31	valuable	valuable	ADJ
fnp-3326	456	32	scientific	scientific	ADJ
fnp-3326	456	33	input	input	NOUN
fnp-3326	456	34	throughout	throughout	ADP
fnp-3326	456	35	the	the	DET
fnp-3326	456	36	project	project	NOUN
fnp-3326	456	37	,	,	PUNCT
fnp-3326	456	38	and	and	CCONJ
fnp-3326	456	39	drs	drs	PROPN
fnp-3326	456	40	.	.	PROPN
fnp-3326	456	41	m.	m.	NOUN
fnp-3326	456	42	and	and	CCONJ
fnp-3326	456	43	p.	p.	NOUN
fnp-3326	456	44	derkinderen	derkinderen	NOUN
fnp-3326	456	45	for	for	ADP
fnp-3326	456	46	critical	critical	ADJ
fnp-3326	456	47	input	input	NOUN
fnp-3326	456	48	on	on	ADP
fnp-3326	456	49	the	the	DET
fnp-3326	456	50	link	link	NOUN
fnp-3326	456	51	between	between	ADP
fnp-3326	456	52	ibd	ibd	PROPN
fnp-3326	456	53	and	and	CCONJ
fnp-3326	456	54	the	the	DET
fnp-3326	456	55	enteric	enteric	ADJ
fnp-3326	456	56	αsyn	αsyn	ADJ
fnp-3326	456	57	accumulation	accumulation	NOUN
fnp-3326	456	58	in	in	ADP
fnp-3326	456	59	humans	human	NOUN
fnp-3326	456	60	.	.	PUNCT
fnp-3326	457	1	p.b	p.b	PROPN
fnp-3326	457	2	.	.	PROPN
fnp-3326	457	3	acknowledges	acknowledge	VERB
fnp-3326	457	4	the	the	DET
fnp-3326	457	5	van	van	PROPN
fnp-3326	457	6	andel	andel	PROPN
fnp-3326	457	7	institute	institute	PROPN
fnp-3326	457	8	and	and	CCONJ
fnp-3326	457	9	the	the	DET
fnp-3326	457	10	many	many	ADJ
fnp-3326	457	11	individuals	individual	NOUN
fnp-3326	457	12	and	and	CCONJ
fnp-3326	457	13	corporations	corporation	NOUN
fnp-3326	457	14	that	that	PRON
fnp-3326	457	15	supported	support	VERB
fnp-3326	457	16	financially	financially	ADV
fnp-3326	457	17	the	the	DET
fnp-3326	457	18	neurodegenerative	neurodegenerative	ADJ
fnp-3326	457	19	research	research	NOUN
fnp-3326	457	20	at	at	ADP
fnp-3326	457	21	van	van	PROPN
fnp-3326	457	22	andel	andel	PROPN
fnp-3326	457	23	institute	institute	PROPN
fnp-3326	457	24	.	.	PUNCT
fnp-3326	458	1	research	research	NOUN
fnp-3326	458	2	at	at	ADP
fnp-3326	458	3	van	van	PROPN
fnp-3326	458	4	andel	andel	PROPN
fnp-3326	458	5	institute	institute	PROPN
fnp-3326	458	6	reported	report	VERB
fnp-3326	458	7	in	in	ADP
fnp-3326	458	8	this	this	DET
fnp-3326	458	9	publication	publication	NOUN
fnp-3326	458	10	was	be	AUX
fnp-3326	458	11	also	also	ADV
fnp-3326	458	12	financially	financially	ADV
fnp-3326	458	13	supported	support	VERB
fnp-3326	458	14	by	by	ADP
fnp-3326	458	15	roche	roche	PROPN
fnp-3326	458	16	through	through	ADP
fnp-3326	458	17	a	a	DET
fnp-3326	458	18	research	research	NOUN
fnp-3326	458	19	collaboration	collaboration	NOUN
fnp-3326	458	20	with	with	ADP
fnp-3326	458	21	p.b	p.b	PROPN
fnp-3326	458	22	.	.	PROPN
fnp-3326	458	23	s.g	s.g	PROPN
fnp-3326	458	24	and	and	CCONJ
fnp-3326	458	25	n.m	n.m	PROPN
fnp-3326	458	26	.	.	PROPN
fnp-3326	458	27	were	be	AUX
fnp-3326	458	28	supported	support	VERB
fnp-3326	458	29	by	by	ADP
fnp-3326	458	30	a	a	DET
fnp-3326	458	31	grant	grant	NOUN
fnp-3326	458	32	from	from	ADP
fnp-3326	458	33	roche	roche	PROPN
fnp-3326	458	34	under	under	ADP
fnp-3326	458	35	the	the	DET
fnp-3326	458	36	roche	roche	PROPN
fnp-3326	458	37	postdoctoral	postdoctoral	ADJ
fnp-3326	458	38	fellowship	fellowship	NOUN
fnp-3326	458	39	(	(	PUNCT
fnp-3326	458	40	rpf	rpf	NOUN
fnp-3326	458	41	)	)	PUNCT
fnp-3326	458	42	program	program	NOUN
fnp-3326	458	43	.	.	PUNCT
fnp-3326	459	1	conflict	conflict	NOUN
fnp-3326	459	2	of	of	ADP
fnp-3326	459	3	interest	interest	NOUN
fnp-3326	459	4	at	at	ADP
fnp-3326	459	5	the	the	DET
fnp-3326	459	6	time	time	NOUN
fnp-3326	459	7	of	of	ADP
fnp-3326	459	8	the	the	DET
fnp-3326	459	9	study	study	NOUN
fnp-3326	459	10	s.g	s.g	PROPN
fnp-3326	459	11	.	.	PROPN
fnp-3326	459	12	and	and	CCONJ
fnp-3326	459	13	n.m	n.m	PROPN
fnp-3326	459	14	.	.	PROPN
fnp-3326	459	15	were	be	AUX
fnp-3326	459	16	roche	roche	PROPN
fnp-3326	459	17	postdoctoral	postdoctoral	ADJ
fnp-3326	459	18	fellows	fellow	NOUN
fnp-3326	459	19	employed	employ	VERB
fnp-3326	459	20	by	by	ADP
fnp-3326	459	21	roche	roche	NOUN
fnp-3326	459	22	and	and	CCONJ
fnp-3326	459	23	l.s	l.s	PROPN
fnp-3326	459	24	.	.	PROPN
fnp-3326	459	25	,	,	PUNCT
fnp-3326	459	26	f.b	f.b	PROPN
fnp-3326	459	27	.	.	PROPN
fnp-3326	459	28	,	,	PUNCT
fnp-3326	459	29	g.d.p	g.d.p	PROPN
fnp-3326	459	30	.	.	PROPN
fnp-3326	459	31	,	,	PUNCT
fnp-3326	459	32	j.s.p	j.s.p	PROPN
fnp-3326	459	33	.	.	PUNCT
fnp-3326	459	34	,	,	PUNCT
fnp-3326	459	35	k.o.s	k.o.s	PROPN
fnp-3326	459	36	.	.	PROPN
fnp-3326	459	37	,	,	PUNCT
fnp-3326	459	38	h.r	h.r	PROPN
fnp-3326	459	39	.	.	PROPN
fnp-3326	459	40	,	,	PUNCT
fnp-3326	459	41	m.h	m.h	PROPN
fnp-3326	459	42	.	.	PROPN
fnp-3326	459	43	,	,	PUNCT
fnp-3326	459	44	m.se	m.se	PROPN
fnp-3326	459	45	.	.	PROPN
fnp-3326	460	1	m.st	m.st	PROPN
fnp-3326	460	2	.	.	PROPN
fnp-3326	460	3	,	,	PUNCT
fnp-3326	460	4	p.m.	p.m.	NOUN
fnp-3326	460	5	,	,	PUNCT
fnp-3326	460	6	a.w	a.w	PROPN
fnp-3326	460	7	.	.	PROPN
fnp-3326	460	8	,	,	PUNCT
fnp-3326	461	1	t.e	t.e	PROPN
fnp-3326	461	2	.	.	PROPN
fnp-3326	461	3	,	,	PUNCT
fnp-3326	461	4	a.h	a.h	PROPN
fnp-3326	461	5	.	.	PROPN
fnp-3326	461	6	and	and	CCONJ
fnp-3326	461	7	m.b	m.b	PROPN
fnp-3326	461	8	.	.	PROPN
fnp-3326	461	9	are	be	AUX
fnp-3326	461	10	or	or	CCONJ
fnp-3326	461	11	were	be	AUX
fnp-3326	461	12	fulltime	fulltime	ADJ
fnp-3326	461	13	employees	employee	NOUN
fnp-3326	461	14	or	or	CCONJ
fnp-3326	461	15	trainees	trainee	NOUN
fnp-3326	461	16	at	at	ADP
fnp-3326	461	17	roche	roche	NOUN
fnp-3326	461	18	and	and	CCONJ
fnp-3326	461	19	they	they	PRON
fnp-3326	461	20	may	may	AUX
fnp-3326	461	21	additionally	additionally	ADV
fnp-3326	461	22	hold	hold	VERB
fnp-3326	461	23	roche	roche	NOUN
fnp-3326	461	24	stock	stock	NOUN
fnp-3326	461	25	/	/	SYM
fnp-3326	461	26	stock	stock	NOUN
fnp-3326	461	27	options	option	NOUN
fnp-3326	461	28	.	.	PUNCT
fnp-3326	462	1	s.g	s.g	PROPN
fnp-3326	462	2	.	.	PROPN
fnp-3326	462	3	and	and	CCONJ
fnp-3326	462	4	l.s	l.s	PROPN
fnp-3326	462	5	.	.	PROPN
fnp-3326	462	6	are	be	AUX
fnp-3326	462	7	currently	currently	ADV
fnp-3326	462	8	employees	employee	NOUN
fnp-3326	462	9	of	of	ADP
fnp-3326	462	10	neurimmune	neurimmune	PROPN
fnp-3326	462	11	ag	ag	PROPN
fnp-3326	462	12	,	,	PUNCT
fnp-3326	462	13	schlieren	schlieren	PROPN
fnp-3326	462	14	,	,	PUNCT
fnp-3326	462	15	switzerland	switzerland	PROPN
fnp-3326	462	16	.	.	PUNCT
fnp-3326	463	1	p.b	p.b	PROPN
fnp-3326	463	2	.	.	PROPN
fnp-3326	463	3	has	have	AUX
fnp-3326	463	4	received	receive	VERB
fnp-3326	463	5	commercial	commercial	ADJ
fnp-3326	463	6	support	support	NOUN
fnp-3326	463	7	as	as	ADP
fnp-3326	463	8	a	a	DET
fnp-3326	463	9	consultant	consultant	NOUN
fnp-3326	463	10	from	from	ADP
fnp-3326	463	11	axial	axial	ADJ
fnp-3326	463	12	biotherapeutics	biotherapeutic	NOUN
fnp-3326	463	13	,	,	PUNCT
fnp-3326	463	14	calico	calico	ADJ
fnp-3326	463	15	life	life	NOUN
fnp-3326	463	16	sciences	science	NOUN
fnp-3326	463	17	,	,	PUNCT
fnp-3326	463	18	curasen	curasen	NOUN
fnp-3326	463	19	,	,	PUNCT
fnp-3326	463	20	fujifilm	fujifilm	NOUN
fnp-3326	463	21	-	-	PUNCT
fnp-3326	463	22	cellular	cellular	ADJ
fnp-3326	463	23	dynamics	dynamic	NOUN
fnp-3326	463	24	international	international	PROPN
fnp-3326	463	25	,	,	PUNCT
fnp-3326	463	26	h.	h.	PROPN
fnp-3326	463	27	lundbeck	lundbeck	PROPN
fnp-3326	463	28	a	a	PROPN
fnp-3326	463	29	/	/	SYM
fnp-3326	463	30	s	s	PROPN
fnp-3326	463	31	,	,	PUNCT
fnp-3326	463	32	and	and	CCONJ
fnp-3326	463	33	idorsia	idorsia	PROPN
fnp-3326	463	34	pharmaceuticals	pharmaceuticals	PROPN
fnp-3326	463	35	ltd	ltd	PROPN
fnp-3326	463	36	.	.	PUNCT
fnp-3326	464	1	he	he	PRON
fnp-3326	464	2	has	have	AUX
fnp-3326	464	3	received	receive	VERB
fnp-3326	464	4	commercial	commercial	ADJ
fnp-3326	464	5	support	support	NOUN
fnp-3326	464	6	for	for	ADP
fnp-3326	464	7	grants	grant	NOUN
fnp-3326	464	8	/	/	SYM
fnp-3326	464	9	research	research	NOUN
fnp-3326	464	10	from	from	ADP
fnp-3326	464	11	h.	h.	PROPN
fnp-3326	464	12	lundbeck	lundbeck	PROPN
fnp-3326	464	13	a	a	PROPN
fnp-3326	464	14	/	/	SYM
fnp-3326	464	15	s	s	NOUN
fnp-3326	464	16	and	and	CCONJ
fnp-3326	464	17	roche	roche	NOUN
fnp-3326	464	18	.	.	PUNCT
fnp-3326	465	1	he	he	PRON
fnp-3326	465	2	has	have	VERB
fnp-3326	465	3	ownership	ownership	NOUN
fnp-3326	465	4	interests	interest	NOUN
fnp-3326	465	5	in	in	ADP
fnp-3326	465	6	acousort	acousort	PROPN
fnp-3326	465	7	ab	ab	PROPN
fnp-3326	465	8	.	.	PUNCT
fnp-3326	466	1	the	the	DET
fnp-3326	466	2	other	other	ADJ
fnp-3326	466	3	authors	author	NOUN
fnp-3326	466	4	declare	declare	VERB
fnp-3326	466	5	that	that	SCONJ
fnp-3326	466	6	they	they	PRON
fnp-3326	466	7	have	have	VERB
fnp-3326	466	8	no	no	DET
fnp-3326	466	9	competing	compete	VERB
fnp-3326	466	10	interest	interest	NOUN
fnp-3326	466	11	with	with	ADP
fnp-3326	466	12	regard	regard	NOUN
fnp-3326	466	13	to	to	ADP
fnp-3326	466	14	this	this	DET
fnp-3326	466	15	research	research	NOUN
fnp-3326	466	16	.	.	PUNCT
fnp-3326	467	1	author	author	NOUN
fnp-3326	467	2	contributions	contribution	NOUN
fnp-3326	467	3	s.g	s.g	PROPN
fnp-3326	467	4	.	.	PROPN
fnp-3326	467	5	,	,	PUNCT
fnp-3326	467	6	n.m	n.m	PROPN
fnp-3326	467	7	.	.	PROPN
fnp-3326	467	8	and	and	CCONJ
fnp-3326	467	9	l.s	l.s	PROPN
fnp-3326	467	10	.	.	PROPN
fnp-3326	467	11	planned	plan	VERB
fnp-3326	467	12	and	and	CCONJ
fnp-3326	467	13	performed	perform	VERB
fnp-3326	467	14	the	the	PRON
fnp-3326	467	15	in	in	ADP
fnp-3326	467	16	vivo	vivo	ADJ
fnp-3326	467	17	experiments	experiment	NOUN
fnp-3326	467	18	,	,	PUNCT
fnp-3326	467	19	colon	colon	NOUN
fnp-3326	467	20	immunostaining	immunostaining	NOUN
fnp-3326	467	21	,	,	PUNCT
fnp-3326	467	22	analysis	analysis	NOUN
fnp-3326	467	23	,	,	PUNCT
fnp-3326	467	24	and	and	CCONJ
fnp-3326	467	25	quantification	quantification	NOUN
fnp-3326	467	26	;	;	PUNCT
fnp-3326	467	27	s.g	s.g	PROPN
fnp-3326	467	28	.	.	PROPN
fnp-3326	467	29	and	and	CCONJ
fnp-3326	467	30	n.m	n.m	PROPN
fnp-3326	467	31	.	.	PROPN
fnp-3326	467	32	drafted	draft	VERB
fnp-3326	467	33	a	a	DET
fnp-3326	467	34	first	first	ADJ
fnp-3326	467	35	version	version	NOUN
fnp-3326	467	36	of	of	ADP
fnp-3326	467	37	the	the	DET
fnp-3326	467	38	manuscript	manuscript	NOUN
fnp-3326	467	39	;	;	PUNCT
fnp-3326	467	40	e.q	e.q	PROPN
fnp-3326	467	41	.	.	PROPN
fnp-3326	467	42	performed	perform	VERB
fnp-3326	467	43	,	,	PUNCT
fnp-3326	467	44	imaged	image	VERB
fnp-3326	467	45	,	,	PUNCT
fnp-3326	467	46	quantitated	quantitated	ADJ
fnp-3326	467	47	pser129	pser129	PROPN
fnp-3326	467	48	,	,	PUNCT
fnp-3326	467	49	th	th	X
fnp-3326	467	50	and	and	CCONJ
fnp-3326	467	51	nissl	nissl	ADV
fnp-3326	467	52	staining	stain	VERB
fnp-3326	467	53	in	in	ADP
fnp-3326	467	54	the	the	DET
fnp-3326	467	55	brain	brain	NOUN
fnp-3326	467	56	sections	section	NOUN
fnp-3326	467	57	,	,	PUNCT
fnp-3326	467	58	and	and	CCONJ
fnp-3326	467	59	drafted	draft	VERB
fnp-3326	467	60	a	a	DET
fnp-3326	467	61	more	more	ADV
fnp-3326	467	62	advanced	advanced	ADJ
fnp-3326	467	63	version	version	NOUN
fnp-3326	467	64	of	of	ADP
fnp-3326	467	65	the	the	DET
fnp-3326	467	66	manuscript	manuscript	NOUN
fnp-3326	467	67	with	with	ADP
fnp-3326	467	68	j.a.s	j.a.s	PROPN
fnp-3326	467	69	.	.	PROPN
fnp-3326	467	70	,	,	PUNCT
fnp-3326	467	71	who	who	PRON
fnp-3326	467	72	also	also	ADV
fnp-3326	467	73	provided	provide	VERB
fnp-3326	467	74	helpful	helpful	ADJ
fnp-3326	467	75	discussion	discussion	NOUN
fnp-3326	467	76	.	.	PUNCT
fnp-3326	468	1	both	both	DET
fnp-3326	468	2	j.a.s	j.a.s	PROPN
fnp-3326	468	3	.	.	PROPN
fnp-3326	468	4	and	and	CCONJ
fnp-3326	468	5	e.q	e.q	PROPN
fnp-3326	468	6	.	.	PROPN
fnp-3326	468	7	were	be	AUX
fnp-3326	468	8	critical	critical	ADJ
fnp-3326	468	9	in	in	ADP
fnp-3326	468	10	revising	revise	VERB
fnp-3326	468	11	the	the	DET
fnp-3326	468	12	manuscript	manuscript	NOUN
fnp-3326	468	13	.	.	PUNCT
fnp-3326	469	1	f.b	f.b	PROPN
fnp-3326	469	2	.	.	PROPN
fnp-3326	469	3	and	and	CCONJ
fnp-3326	469	4	k.o.s	k.o.s	PROPN
fnp-3326	469	5	.	.	PUNCT
fnp-3326	469	6	supported	support	VERB
fnp-3326	469	7	the	the	DET
fnp-3326	469	8	image	image	NOUN
fnp-3326	469	9	acquisition	acquisition	NOUN
fnp-3326	469	10	and	and	CCONJ
fnp-3326	469	11	image	image	NOUN
fnp-3326	469	12	analysis	analysis	NOUN
fnp-3326	469	13	for	for	ADP
fnp-3326	469	14	the	the	DET
fnp-3326	469	15	colon	colon	NOUN
fnp-3326	469	16	samples	sample	NOUN
fnp-3326	469	17	;	;	PUNCT
fnp-3326	469	18	m.st	m.st	PROPN
fnp-3326	469	19	.	.	PROPN
fnp-3326	469	20	performed	perform	VERB
fnp-3326	469	21	imaging	imaging	NOUN
fnp-3326	469	22	and	and	CCONJ
fnp-3326	469	23	data	datum	NOUN
fnp-3326	469	24	analysis	analysis	NOUN
fnp-3326	469	25	of	of	ADP
fnp-3326	469	26	experiments	experiment	NOUN
fnp-3326	469	27	with	with	ADP
fnp-3326	469	28	wild	wild	ADJ
fnp-3326	469	29	type	type	NOUN
fnp-3326	469	30	mice	mouse	NOUN
fnp-3326	469	31	;	;	PUNCT
fnp-3326	469	32	g.d.p	g.d.p	ADJ
fnp-3326	469	33	.	.	PUNCT
fnp-3326	470	1	and	and	CCONJ
fnp-3326	470	2	j.s.p	j.s.p	PROPN
fnp-3326	470	3	.	.	PUNCT
fnp-3326	470	4	performed	perform	VERB
fnp-3326	470	5	statistical	statistical	ADJ
fnp-3326	470	6	analysis	analysis	NOUN
fnp-3326	470	7	of	of	ADP
fnp-3326	470	8	the	the	DET
fnp-3326	470	9	dss	dss	NOUN
fnp-3326	470	10	experiments	experiment	NOUN
fnp-3326	470	11	;	;	PUNCT
fnp-3326	470	12	h.r	h.r	PROPN
fnp-3326	470	13	.	.	PROPN
fnp-3326	470	14	and	and	CCONJ
fnp-3326	470	15	m.h	m.h	PROPN
fnp-3326	470	16	.	.	PROPN
fnp-3326	470	17	performed	perform	VERB
fnp-3326	470	18	mrna	mrna	PROPN
fnp-3326	470	19	analyses	analysis	NOUN
fnp-3326	470	20	;	;	PUNCT
fnp-3326	470	21	m.se	m.se	PROPN
fnp-3326	470	22	.	.	PROPN
fnp-3326	470	23	trained	trained	PROPN
fnp-3326	470	24	s.g	s.g	PROPN
fnp-3326	470	25	.	.	PROPN
fnp-3326	470	26	and	and	CCONJ
fnp-3326	470	27	l.s	l.s	PROPN
fnp-3326	470	28	.	.	PROPN
fnp-3326	470	29	on	on	ADP
fnp-3326	470	30	mouse	mouse	NOUN
fnp-3326	470	31	necropsy	necropsy	NOUN
fnp-3326	470	32	and	and	CCONJ
fnp-3326	470	33	supported	support	VERB
fnp-3326	470	34	their	their	PRON
fnp-3326	470	35	work	work	NOUN
fnp-3326	470	36	;	;	PUNCT
fnp-3326	470	37	p.m.	p.m.	NOUN
fnp-3326	470	38	performed	perform	VERB
fnp-3326	470	39	expert	expert	NOUN
fnp-3326	470	40	pathology	pathology	NOUN
fnp-3326	470	41	staging	stage	VERB
fnp-3326	470	42	on	on	ADP
fnp-3326	470	43	leukocyte	leukocyte	ADJ
fnp-3326	470	44	infiltration	infiltration	NOUN
fnp-3326	470	45	;	;	PUNCT
fnp-3326	470	46	t.e	t.e	PROPN
fnp-3326	470	47	.	.	PROPN
fnp-3326	470	48	and	and	CCONJ
fnp-3326	470	49	a.w	a.w	PROPN
fnp-3326	470	50	.	.	PROPN
fnp-3326	470	51	provided	provide	VERB
fnp-3326	470	52	migg	migg	ADJ
fnp-3326	470	53	-	-	PUNCT
fnp-3326	470	54	mil-10	mil-10	NOUN
fnp-3326	470	55	fusion	fusion	NOUN
fnp-3326	470	56	proteins	protein	NOUN
fnp-3326	470	57	and	and	CCONJ
fnp-3326	470	58	measured	measure	VERB
fnp-3326	470	59	serum	serum	NOUN
fnp-3326	470	60	exposure	exposure	NOUN
fnp-3326	470	61	;	;	PUNCT
fnp-3326	470	62	z.m	z.m	PROPN
fnp-3326	470	63	.	.	PROPN
fnp-3326	470	64	performed	perform	VERB
fnp-3326	470	65	statistical	statistical	ADJ
fnp-3326	470	66	analysis	analysis	NOUN
fnp-3326	470	67	for	for	ADP
fnp-3326	470	68	the	the	DET
fnp-3326	470	69	pser129	pser129	PROPN
fnp-3326	470	70	αsyn	αsyn	PROPN
fnp-3326	470	71	immunohistochemistry	immunohistochemistry	PROPN
fnp-3326	470	72	data	data	PROPN
fnp-3326	470	73	.	.	PUNCT
fnp-3326	471	1	a.s	a.s	PROPN
fnp-3326	471	2	.	.	PROPN
fnp-3326	471	3	contributed	contribute	VERB
fnp-3326	471	4	with	with	ADP
fnp-3326	471	5	scientific	scientific	ADJ
fnp-3326	471	6	and	and	CCONJ
fnp-3326	471	7	veterinary	veterinary	ADJ
fnp-3326	471	8	expert	expert	NOUN
fnp-3326	471	9	input	input	NOUN
fnp-3326	471	10	for	for	ADP
fnp-3326	471	11	implementation	implementation	NOUN
fnp-3326	471	12	and	and	CCONJ
fnp-3326	471	13	analysis	analysis	NOUN
fnp-3326	471	14	of	of	ADP
fnp-3326	471	15	the	the	DET
fnp-3326	471	16	dss	dss	NOUN
fnp-3326	471	17	colitis	colitis	NOUN
fnp-3326	471	18	model	model	NOUN
fnp-3326	471	19	at	at	ADP
fnp-3326	471	20	roche	roche	PROPN
fnp-3326	471	21	.	.	PUNCT
fnp-3326	472	1	m.l.e.g	m.l.e.g	PROPN
fnp-3326	472	2	.	.	PROPN
fnp-3326	472	3	provided	provide	VERB
fnp-3326	472	4	helpful	helpful	ADJ
fnp-3326	472	5	discussion	discussion	NOUN
fnp-3326	472	6	and	and	CCONJ
fnp-3326	472	7	project	project	NOUN
fnp-3326	472	8	planning	planning	NOUN
fnp-3326	472	9	.	.	PUNCT
fnp-3326	473	1	a.h	a.h	PROPN
fnp-3326	473	2	.	.	PROPN
fnp-3326	473	3	co	co	PROPN
fnp-3326	473	4	-	-	ADJ
fnp-3326	473	5	mentored	mentored	ADJ
fnp-3326	473	6	s.g	s.g	PROPN
fnp-3326	473	7	.	.	PROPN
fnp-3326	473	8	and	and	CCONJ
fnp-3326	473	9	n.m	n.m	PROPN
fnp-3326	473	10	.	.	PROPN
fnp-3326	473	11	,	,	PUNCT
fnp-3326	473	12	performed	perform	VERB
fnp-3326	473	13	expert	expert	NOUN
fnp-3326	473	14	pathology	pathology	NOUN
fnp-3326	473	15	staging	stage	VERB
fnp-3326	473	16	on	on	ADP
fnp-3326	473	17	leukocyte	leukocyte	ADJ
fnp-3326	473	18	infiltration	infiltration	NOUN
fnp-3326	473	19	and	and	CCONJ
fnp-3326	473	20	contributed	contribute	VERB
fnp-3326	473	21	to	to	ADP
fnp-3326	473	22	experimental	experimental	ADJ
fnp-3326	473	23	planning	planning	NOUN
fnp-3326	473	24	.	.	PUNCT
fnp-3326	474	1	c.m	c.m	PROPN
fnp-3326	474	2	.	.	PROPN
fnp-3326	474	3	trained	train	VERB
fnp-3326	474	4	s.g	s.g	PROPN
fnp-3326	474	5	.	.	PROPN
fnp-3326	474	6	on	on	ADP
fnp-3326	474	7	the	the	DET
fnp-3326	474	8	colitis	colitis	NOUN
fnp-3326	474	9	model	model	NOUN
fnp-3326	474	10	and	and	CCONJ
fnp-3326	474	11	provided	provide	VERB
fnp-3326	474	12	expert	expert	NOUN
fnp-3326	474	13	input	input	NOUN
fnp-3326	474	14	on	on	ADP
fnp-3326	474	15	the	the	DET
fnp-3326	474	16	experimental	experimental	ADJ
fnp-3326	474	17	ibd	ibd	PROPN
fnp-3326	474	18	model	model	NOUN
fnp-3326	474	19	.	.	PUNCT
fnp-3326	475	1	m.b	m.b	PROPN
fnp-3326	475	2	.	.	PROPN
fnp-3326	476	1	and	and	CCONJ
fnp-3326	476	2	p.b	p.b	PROPN
fnp-3326	476	3	.	.	PROPN
fnp-3326	476	4	co	co	VERB
fnp-3326	476	5	-	-	ADJ
fnp-3326	476	6	mentored	mentored	ADJ
fnp-3326	476	7	roche	roche	PROPN
fnp-3326	476	8	postdoctoral	postdoctoral	PROPN
fnp-3326	476	9	fellows	fellows	PROPN
fnp-3326	476	10	s.g	s.g	PROPN
fnp-3326	476	11	.	.	PROPN
fnp-3326	476	12	and	and	CCONJ
fnp-3326	476	13	n.m	n.m	PROPN
fnp-3326	476	14	.	.	PROPN
fnp-3326	476	15	,	,	PUNCT
fnp-3326	476	16	conceived	conceive	VERB
fnp-3326	476	17	and	and	CCONJ
fnp-3326	476	18	oversaw	oversee	VERB
fnp-3326	476	19	the	the	DET
fnp-3326	476	20	study	study	NOUN
fnp-3326	476	21	,	,	PUNCT
fnp-3326	476	22	and	and	CCONJ
fnp-3326	476	23	performed	perform	VERB
fnp-3326	476	24	experimental	experimental	ADJ
fnp-3326	476	25	planning	planning	NOUN
fnp-3326	476	26	;	;	PUNCT
fnp-3326	476	27	m.b	m.b	PROPN
fnp-3326	476	28	.	.	PROPN
fnp-3326	476	29	,	,	PUNCT
fnp-3326	476	30	p.b	p.b	PROPN
fnp-3326	476	31	.	.	PROPN
fnp-3326	476	32	j.a.s	j.a.s	PROPN
fnp-3326	476	33	.	.	PROPN
fnp-3326	477	1	and	and	CCONJ
fnp-3326	477	2	e.q	e.q	PROPN
fnp-3326	477	3	.	.	PROPN
fnp-3326	477	4	wrote	write	VERB
fnp-3326	477	5	the	the	DET
fnp-3326	477	6	final	final	ADJ
fnp-3326	477	7	version	version	NOUN
fnp-3326	477	8	of	of	ADP
fnp-3326	477	9	the	the	DET
fnp-3326	477	10	manuscript	manuscript	NOUN
fnp-3326	477	11	.	.	PUNCT
fnp-3326	478	1	all	all	DET
fnp-3326	478	2	authors	author	NOUN
fnp-3326	478	3	read	read	VERB
fnp-3326	478	4	and	and	CCONJ
fnp-3326	478	5	approved	approve	VERB
fnp-3326	478	6	the	the	DET
fnp-3326	478	7	final	final	ADJ
fnp-3326	478	8	manuscript	manuscript	NOUN
fnp-3326	478	9	.	.	PUNCT
fnp-3326	479	1	references	reference	NOUN
fnp-3326	479	2	1	1	NUM
fnp-3326	479	3	.	.	PUNCT
fnp-3326	479	4	tysnes	tysne	NOUN
fnp-3326	480	1	o	o	PROPN
fnp-3326	480	2	-	-	SYM
fnp-3326	480	3	b	b	PROPN
fnp-3326	480	4	,	,	PUNCT
fnp-3326	480	5	storstein	storstein	ADJ
fnp-3326	480	6	a.	a.	NOUN
fnp-3326	480	7	epidemiology	epidemiology	NOUN
fnp-3326	480	8	of	of	ADP
fnp-3326	480	9	parkinson	parkinson	NOUN
fnp-3326	480	10	’s	’s	PART
fnp-3326	480	11	disease	disease	NOUN
fnp-3326	480	12	.	.	PUNCT
fnp-3326	481	1	j	j	PROPN
fnp-3326	481	2	neural	neural	ADJ
fnp-3326	481	3	transm	transm	PROPN
fnp-3326	481	4	(	(	PUNCT
fnp-3326	481	5	vienna	vienna	PROPN
fnp-3326	481	6	)	)	PUNCT
fnp-3326	481	7	.	.	PUNCT
fnp-3326	482	1	2017;124:901–5	2017;124:901–5	NUM
fnp-3326	482	2	.	.	PUNCT
fnp-3326	483	1	2	2	NUM
fnp-3326	483	2	.	.	X
fnp-3326	483	3	spillantini	spillantini	PROPN
fnp-3326	483	4	mg	mg	PROPN
fnp-3326	483	5	,	,	PUNCT
fnp-3326	483	6	goedert	goedert	PROPN
fnp-3326	483	7	m.	m.	NOUN
fnp-3326	483	8	neurodegeneration	neurodegeneration	NOUN
fnp-3326	483	9	and	and	CCONJ
fnp-3326	483	10	the	the	DET
fnp-3326	483	11	ordered	order	VERB
fnp-3326	483	12	assembly	assembly	NOUN
fnp-3326	483	13	of	of	ADP
fnp-3326	483	14	α	α	NOUN
fnp-3326	483	15	-	-	PUNCT
fnp-3326	483	16	synuclein	synuclein	NOUN
fnp-3326	483	17	.	.	PUNCT
fnp-3326	484	1	cell	cell	NOUN
fnp-3326	484	2	tissue	tissue	NOUN
fnp-3326	484	3	res	re	NOUN
fnp-3326	484	4	.	.	PUNCT
fnp-3326	485	1	2017;373:137–48	2017;373:137–48	NUM
fnp-3326	485	2	.	.	X
fnp-3326	486	1	3	3	X
fnp-3326	486	2	.	.	X
fnp-3326	486	3	del	del	PROPN
fnp-3326	486	4	tredici	tredici	PROPN
fnp-3326	486	5	k	k	PROPN
fnp-3326	486	6	,	,	PUNCT
fnp-3326	486	7	braak	braak	PROPN
fnp-3326	486	8	h.	h.	PROPN
fnp-3326	486	9	lewy	lewy	PROPN
fnp-3326	486	10	pathology	pathology	PROPN
fnp-3326	486	11	and	and	CCONJ
fnp-3326	486	12	neurodegeneration	neurodegeneration	NOUN
fnp-3326	486	13	in	in	ADP
fnp-3326	486	14	premotor	premotor	ADJ
fnp-3326	486	15	parkinson	parkinson	NOUN
fnp-3326	486	16	’s	’s	PART
fnp-3326	486	17	disease	disease	NOUN
fnp-3326	486	18	.	.	PUNCT
fnp-3326	487	1	mov	mov	NOUN
fnp-3326	487	2	disord	disord	NOUN
fnp-3326	487	3	.	.	PUNCT
fnp-3326	488	1	2012;27:597–607	2012;27:597–607	PROPN
fnp-3326	488	2	.	.	PUNCT
fnp-3326	489	1	4	4	X
fnp-3326	489	2	.	.	X
fnp-3326	489	3	polymeropoulos	polymeropoulos	PROPN
fnp-3326	489	4	mh	mh	PROPN
fnp-3326	489	5	,	,	PUNCT
fnp-3326	489	6	lavedan	lavedan	PROPN
fnp-3326	489	7	c	c	PROPN
fnp-3326	489	8	,	,	PUNCT
fnp-3326	489	9	leroy	leroy	PROPN
fnp-3326	489	10	e	e	PROPN
fnp-3326	489	11	,	,	PUNCT
fnp-3326	489	12	ide	ide	NOUN
fnp-3326	489	13	se	se	X
fnp-3326	489	14	,	,	PUNCT
fnp-3326	489	15	dehejia	dehejia	NOUN
fnp-3326	489	16	a	a	PRON
fnp-3326	489	17	,	,	PUNCT
fnp-3326	489	18	dutra	dutra	ADJ
fnp-3326	489	19	a	a	X
fnp-3326	489	20	,	,	PUNCT
fnp-3326	489	21	et	et	PROPN
fnp-3326	489	22	al	al	PROPN
fnp-3326	489	23	.	.	PROPN
fnp-3326	489	24	mutation	mutation	NOUN
fnp-3326	489	25	in	in	ADP
fnp-3326	489	26	the	the	DET
fnp-3326	489	27	alpha	alpha	NOUN
fnp-3326	489	28	-	-	PUNCT
fnp-3326	489	29	synuclein	synuclein	NOUN
fnp-3326	489	30	gene	gene	NOUN
fnp-3326	489	31	identified	identify	VERB
fnp-3326	489	32	in	in	ADP
fnp-3326	489	33	families	family	NOUN
fnp-3326	489	34	with	with	ADP
fnp-3326	489	35	parkinson	parkinson	NOUN
fnp-3326	489	36	’s	’s	PART
fnp-3326	489	37	disease	disease	NOUN
fnp-3326	489	38	.	.	PUNCT
fnp-3326	490	1	science	science	NOUN
fnp-3326	490	2	.	.	PUNCT
fnp-3326	491	1	1997;276:2045–7	1997;276:2045–7	ADJ
fnp-3326	491	2	.	.	PUNCT
fnp-3326	492	1	5	5	NUM
fnp-3326	492	2	.	.	X
fnp-3326	492	3	schrag	schrag	PROPN
fnp-3326	492	4	a	a	PROPN
fnp-3326	492	5	,	,	PUNCT
fnp-3326	492	6	horsfall	horsfall	PROPN
fnp-3326	492	7	l	l	PROPN
fnp-3326	492	8	,	,	PUNCT
fnp-3326	492	9	walters	walters	PROPN
fnp-3326	492	10	k	k	PROPN
fnp-3326	492	11	,	,	PUNCT
fnp-3326	492	12	noyce	noyce	PROPN
fnp-3326	492	13	a	a	PROPN
fnp-3326	492	14	,	,	PUNCT
fnp-3326	492	15	petersen	petersen	PROPN
fnp-3326	492	16	i.	i.	PROPN
fnp-3326	492	17	prediagnostic	prediagnostic	PROPN
fnp-3326	492	18	presentations	presentation	NOUN
fnp-3326	492	19	of	of	ADP
fnp-3326	492	20	parkinson	parkinson	NOUN
fnp-3326	492	21	’s	’s	PART
fnp-3326	492	22	disease	disease	NOUN
fnp-3326	492	23	in	in	ADP
fnp-3326	492	24	primary	primary	ADJ
fnp-3326	492	25	care	care	NOUN
fnp-3326	492	26	:	:	PUNCT
fnp-3326	492	27	a	a	DET
fnp-3326	492	28	case	case	NOUN
fnp-3326	492	29	-	-	PUNCT
fnp-3326	492	30	control	control	NOUN
fnp-3326	492	31	study	study	NOUN
fnp-3326	492	32	.	.	PUNCT
fnp-3326	493	1	lancet	lancet	PROPN
fnp-3326	493	2	neurol	neurol	PROPN
fnp-3326	493	3	.	.	PUNCT
fnp-3326	494	1	2015;14:57–64	2015;14:57–64	NUM
fnp-3326	494	2	.	.	PROPN
fnp-3326	494	3	6	6	NUM
fnp-3326	494	4	.	.	X
fnp-3326	494	5	gaenslen	gaenslen	VERB
fnp-3326	494	6	a	a	PRON
fnp-3326	494	7	,	,	PUNCT
fnp-3326	494	8	swid	swid	NOUN
fnp-3326	494	9	i	i	PRON
fnp-3326	494	10	,	,	PUNCT
fnp-3326	494	11	liepelt	liepelt	NOUN
fnp-3326	494	12	-	-	PUNCT
fnp-3326	494	13	scarfone	scarfone	NOUN
fnp-3326	495	1	i	i	PROPN
fnp-3326	495	2	,	,	PUNCT
fnp-3326	495	3	godau	godau	PROPN
fnp-3326	495	4	j	j	PROPN
fnp-3326	495	5	,	,	PUNCT
fnp-3326	495	6	berg	berg	PROPN
fnp-3326	495	7	d.	d.	PROPN
fnp-3326	495	8	the	the	DET
fnp-3326	495	9	patients	patient	NOUN
fnp-3326	495	10	’	’	PART
fnp-3326	495	11	perception	perception	NOUN
fnp-3326	495	12	of	of	ADP
fnp-3326	495	13	prodromal	prodromal	ADJ
fnp-3326	495	14	symptoms	symptom	NOUN
fnp-3326	495	15	before	before	ADP
fnp-3326	495	16	the	the	DET
fnp-3326	495	17	initial	initial	ADJ
fnp-3326	495	18	diagnosis	diagnosis	NOUN
fnp-3326	495	19	of	of	ADP
fnp-3326	495	20	parkinson	parkinson	NOUN
fnp-3326	495	21	’s	’s	PART
fnp-3326	495	22	disease	disease	NOUN
fnp-3326	495	23	.	.	PUNCT
fnp-3326	496	1	mov	mov	NOUN
fnp-3326	496	2	disord	disord	NOUN
fnp-3326	496	3	.	.	PUNCT
fnp-3326	497	1	2011;26:653–8	2011;26:653–8	NUM
fnp-3326	497	2	.	.	PUNCT
fnp-3326	498	1	7	7	X
fnp-3326	498	2	.	.	X
fnp-3326	498	3	pont	pont	NOUN
fnp-3326	498	4	-	-	PUNCT
fnp-3326	498	5	sunyer	sunyer	PROPN
fnp-3326	498	6	c	c	PROPN
fnp-3326	498	7	,	,	PUNCT
fnp-3326	498	8	hotter	hot	ADJ
fnp-3326	498	9	a	a	PRON
fnp-3326	498	10	,	,	PUNCT
fnp-3326	498	11	gaig	gaig	PROPN
fnp-3326	498	12	c	c	NOUN
fnp-3326	498	13	,	,	PUNCT
fnp-3326	498	14	seppi	seppi	PROPN
fnp-3326	498	15	k	k	NOUN
fnp-3326	498	16	,	,	PUNCT
fnp-3326	498	17	compta	compta	VERB
fnp-3326	498	18	y	y	PROPN
fnp-3326	498	19	,	,	PUNCT
fnp-3326	498	20	katzenschlager	katzenschlager	ADJ
fnp-3326	498	21	r	r	NOUN
fnp-3326	498	22	,	,	PUNCT
fnp-3326	498	23	et	et	PROPN
fnp-3326	498	24	al	al	PROPN
fnp-3326	498	25	.	.	PUNCT
fnp-3326	499	1	the	the	DET
fnp-3326	499	2	onset	onset	NOUN
fnp-3326	499	3	of	of	ADP
fnp-3326	499	4	nonmotor	nonmotor	NOUN
fnp-3326	499	5	symptoms	symptom	NOUN
fnp-3326	499	6	in	in	ADP
fnp-3326	499	7	parkinson	parkinson	NOUN
fnp-3326	499	8	’s	’s	PART
fnp-3326	499	9	disease	disease	NOUN
fnp-3326	499	10	(	(	PUNCT
fnp-3326	499	11	the	the	DET
fnp-3326	499	12	onset	onset	ADJ
fnp-3326	499	13	pd	pd	PROPN
fnp-3326	499	14	study	study	PROPN
fnp-3326	499	15	)	)	PUNCT
fnp-3326	499	16	.	.	PUNCT
fnp-3326	500	1	mov	mov	NOUN
fnp-3326	500	2	disord	disord	NOUN
fnp-3326	500	3	.	.	PUNCT
fnp-3326	501	1	2015;30:229–37	2015;30:229–37	NUM
fnp-3326	501	2	.	.	NOUN
fnp-3326	502	1	8	8	NUM
fnp-3326	502	2	.	.	PUNCT
fnp-3326	503	1	berg	berg	PROPN
fnp-3326	503	2	d	d	PROPN
fnp-3326	503	3	,	,	PUNCT
fnp-3326	503	4	godau	godau	PROPN
fnp-3326	503	5	j	j	PROPN
fnp-3326	503	6	,	,	PUNCT
fnp-3326	503	7	seppi	seppi	PROPN
fnp-3326	503	8	k	k	PROPN
fnp-3326	503	9	,	,	PUNCT
fnp-3326	503	10	behnke	behnke	PROPN
fnp-3326	503	11	s	s	PROPN
fnp-3326	503	12	,	,	PUNCT
fnp-3326	503	13	liepelt	liepelt	NOUN
fnp-3326	503	14	-	-	PUNCT
fnp-3326	503	15	scarfone	scarfone	NOUN
fnp-3326	504	1	i	i	PROPN
fnp-3326	504	2	,	,	PUNCT
fnp-3326	504	3	lerche	lerche	PROPN
fnp-3326	504	4	s	s	PROPN
fnp-3326	504	5	,	,	PUNCT
fnp-3326	504	6	et	et	PROPN
fnp-3326	504	7	al	al	PROPN
fnp-3326	504	8	.	.	PUNCT
fnp-3326	505	1	the	the	DET
fnp-3326	505	2	prips	prip	NOUN
fnp-3326	505	3	study	study	NOUN
fnp-3326	505	4	:	:	PUNCT
fnp-3326	505	5	screening	screen	VERB
fnp-3326	505	6	battery	battery	NOUN
fnp-3326	505	7	for	for	ADP
fnp-3326	505	8	subjects	subject	NOUN
fnp-3326	505	9	at	at	ADP
fnp-3326	505	10	risk	risk	NOUN
fnp-3326	505	11	for	for	ADP
fnp-3326	505	12	parkinson	parkinson	NOUN
fnp-3326	505	13	’s	’s	PART
fnp-3326	505	14	disease	disease	NOUN
fnp-3326	505	15	.	.	PUNCT
fnp-3326	506	1	eur	eur	PROPN
fnp-3326	506	2	j	j	PROPN
fnp-3326	506	3	neurol	neurol	NOUN
fnp-3326	506	4	.	.	PUNCT
fnp-3326	507	1	2013;20:102–8	2013;20:102–8	NUM
fnp-3326	507	2	.	.	X
fnp-3326	507	3	9	9	X
fnp-3326	507	4	.	.	X
fnp-3326	507	5	postuma	postuma	PROPN
fnp-3326	507	6	rb	rb	PROPN
fnp-3326	507	7	,	,	PUNCT
fnp-3326	507	8	gagnon	gagnon	PROPN
fnp-3326	507	9	j	j	PROPN
fnp-3326	507	10	-	-	PROPN
fnp-3326	507	11	f	f	PROPN
fnp-3326	507	12	,	,	PUNCT
fnp-3326	507	13	bertrand	bertrand	PROPN
fnp-3326	507	14	j	j	PROPN
fnp-3326	507	15	-	-	PUNCT
fnp-3326	507	16	a	a	PROPN
fnp-3326	507	17	,	,	PUNCT
fnp-3326	507	18	génier	génier	PROPN
fnp-3326	507	19	marchand	marchand	PROPN
fnp-3326	507	20	d	d	PROPN
fnp-3326	507	21	,	,	PUNCT
fnp-3326	507	22	montplaisir	montplaisir	PROPN
fnp-3326	507	23	jy	jy	PROPN
fnp-3326	507	24	.	.	PROPN
fnp-3326	507	25	parkinson	parkinson	PROPN
fnp-3326	507	26	risk	risk	NOUN
fnp-3326	507	27	in	in	ADP
fnp-3326	507	28	idiopathic	idiopathic	ADJ
fnp-3326	507	29	rem	rem	PUNCT
fnp-3326	507	30	sleep	sleep	NOUN
fnp-3326	507	31	behavior	behavior	NOUN
fnp-3326	507	32	disorder	disorder	NOUN
fnp-3326	507	33	:	:	PUNCT
fnp-3326	507	34	preparing	prepare	VERB
fnp-3326	507	35	for	for	ADP
fnp-3326	507	36	neuroprotective	neuroprotective	ADJ
fnp-3326	507	37	trials	trial	NOUN
fnp-3326	507	38	.	.	PUNCT
fnp-3326	508	1	neurology	neurology	NOUN
fnp-3326	508	2	.	.	PUNCT
fnp-3326	509	1	2015;84:1104–13	2015;84:1104–13	NUM
fnp-3326	509	2	.	.	PUNCT
fnp-3326	510	1	10	10	NUM
fnp-3326	510	2	.	.	PUNCT
fnp-3326	511	1	abbott	abbott	PROPN
fnp-3326	511	2	rd	rd	PROPN
fnp-3326	511	3	,	,	PUNCT
fnp-3326	511	4	petrovitch	petrovitch	VERB
fnp-3326	511	5	h	h	NOUN
fnp-3326	511	6	,	,	PUNCT
fnp-3326	511	7	white	white	PROPN
fnp-3326	511	8	lr	lr	PROPN
fnp-3326	511	9	,	,	PUNCT
fnp-3326	511	10	masaki	masaki	PROPN
fnp-3326	511	11	kh	kh	PROPN
fnp-3326	511	12	,	,	PUNCT
fnp-3326	511	13	tanner	tanner	NOUN
fnp-3326	511	14	cm	cm	NOUN
fnp-3326	511	15	,	,	PUNCT
fnp-3326	511	16	curb	curb	NOUN
fnp-3326	511	17	jd	jd	PROPN
fnp-3326	511	18	,	,	PUNCT
fnp-3326	511	19	et	et	PROPN
fnp-3326	511	20	al	al	PROPN
fnp-3326	511	21	.	.	PROPN
fnp-3326	511	22	frequency	frequency	PROPN
fnp-3326	511	23	of	of	ADP
fnp-3326	511	24	bowel	bowel	NOUN
fnp-3326	511	25	movements	movement	NOUN
fnp-3326	511	26	and	and	CCONJ
fnp-3326	511	27	the	the	DET
fnp-3326	511	28	future	future	ADJ
fnp-3326	511	29	risk	risk	NOUN
fnp-3326	511	30	of	of	ADP
fnp-3326	511	31	parkinson	parkinson	NOUN
fnp-3326	511	32	’s	’s	PART
fnp-3326	511	33	disease	disease	NOUN
fnp-3326	511	34	.	.	PUNCT
fnp-3326	512	1	neurology	neurology	NOUN
fnp-3326	512	2	.	.	PUNCT
fnp-3326	513	1	2001;57:456–62	2001;57:456–62	NUM
fnp-3326	513	2	.	.	NOUN
fnp-3326	513	3	11	11	NUM
fnp-3326	513	4	.	.	PUNCT
fnp-3326	514	1	savica	savica	NOUN
fnp-3326	514	2	r	r	PROPN
fnp-3326	514	3	,	,	PUNCT
fnp-3326	514	4	carlin	carlin	PROPN
fnp-3326	514	5	jm	jm	PROPN
fnp-3326	514	6	,	,	PUNCT
fnp-3326	514	7	grossardt	grossardt	ADJ
fnp-3326	514	8	br	br	PROPN
fnp-3326	514	9	,	,	PUNCT
fnp-3326	514	10	bower	bower	PROPN
fnp-3326	514	11	jh	jh	PROPN
fnp-3326	514	12	,	,	PUNCT
fnp-3326	514	13	ahlskog	ahlskog	PROPN
fnp-3326	514	14	je	je	PROPN
fnp-3326	514	15	,	,	PUNCT
fnp-3326	514	16	maraganore	maraganore	PROPN
fnp-3326	514	17	dm	dm	PROPN
fnp-3326	514	18	,	,	PUNCT
fnp-3326	514	19	et	et	PROPN
fnp-3326	514	20	al	al	PROPN
fnp-3326	514	21	.	.	PROPN
fnp-3326	515	1	medical	medical	PROPN
fnp-3326	515	2	records	record	NOUN
fnp-3326	515	3	documentation	documentation	NOUN
fnp-3326	515	4	of	of	ADP
fnp-3326	515	5	constipation	constipation	NOUN
fnp-3326	515	6	preceding	precede	VERB
fnp-3326	515	7	parkinson	parkinson	NOUN
fnp-3326	515	8	disease	disease	NOUN
fnp-3326	515	9	:	:	PUNCT
fnp-3326	515	10	a	a	DET
fnp-3326	515	11	case	case	NOUN
fnp-3326	515	12	-	-	PUNCT
fnp-3326	515	13	control	control	NOUN
fnp-3326	515	14	study	study	NOUN
fnp-3326	515	15	.	.	PUNCT
fnp-3326	516	1	neurology	neurology	NOUN
fnp-3326	516	2	.	.	PUNCT
fnp-3326	517	1	2009;73:1752–8	2009;73:1752–8	X
fnp-3326	517	2	.	.	PUNCT
fnp-3326	518	1	12	12	NUM
fnp-3326	518	2	.	.	PUNCT
fnp-3326	519	1	mahlknecht	mahlknecht	PROPN
fnp-3326	519	2	p	p	NOUN
fnp-3326	519	3	,	,	PUNCT
fnp-3326	519	4	seppi	seppi	PROPN
fnp-3326	519	5	k	k	PROPN
fnp-3326	519	6	,	,	PUNCT
fnp-3326	519	7	poewe	poewe	PROPN
fnp-3326	519	8	w.	w.	PROPN
fnp-3326	519	9	the	the	DET
fnp-3326	519	10	concept	concept	NOUN
fnp-3326	519	11	of	of	ADP
fnp-3326	519	12	prodromal	prodromal	ADJ
fnp-3326	519	13	parkinson	parkinson	NOUN
fnp-3326	519	14	’s	’s	PART
fnp-3326	519	15	disease	disease	NOUN
fnp-3326	519	16	.	.	PUNCT
fnp-3326	520	1	j	j	PROPN
fnp-3326	520	2	parkinsons	parkinson	VERB
fnp-3326	520	3	dis	dis	PROPN
fnp-3326	520	4	.	.	PUNCT
fnp-3326	521	1	5:681–97	5:681–97	X
fnp-3326	521	2	.	.	PUNCT
fnp-3326	522	1	13	13	NUM
fnp-3326	522	2	.	.	PUNCT
fnp-3326	523	1	braak	braak	PROPN
fnp-3326	523	2	h	h	PROPN
fnp-3326	523	3	,	,	PUNCT
fnp-3326	523	4	de	de	PROPN
fnp-3326	523	5	vos	vos	PROPN
fnp-3326	523	6	rai	rai	PROPN
fnp-3326	523	7	,	,	PUNCT
fnp-3326	523	8	bohl	bohl	PROPN
fnp-3326	523	9	j	j	PROPN
fnp-3326	523	10	,	,	PUNCT
fnp-3326	523	11	del	del	PROPN
fnp-3326	523	12	tredici	tredici	PROPN
fnp-3326	523	13	k.	k.	PROPN
fnp-3326	523	14	gastric	gastric	PROPN
fnp-3326	523	15	alpha	alpha	PROPN
fnp-3326	523	16	-	-	PUNCT
fnp-3326	523	17	synuclein	synuclein	NOUN
fnp-3326	523	18	immunoreactive	immunoreactive	ADJ
fnp-3326	523	19	inclusions	inclusion	NOUN
fnp-3326	523	20	in	in	ADP
fnp-3326	523	21	meissner	meissner	PROPN
fnp-3326	523	22	’s	’s	PART
fnp-3326	523	23	and	and	CCONJ
fnp-3326	523	24	auerbach	auerbach	VERB
fnp-3326	523	25	’s	’s	PART
fnp-3326	523	26	plexuses	plexus	NOUN
fnp-3326	523	27	in	in	ADP
fnp-3326	523	28	cases	case	NOUN
fnp-3326	523	29	staged	stage	VERB
fnp-3326	523	30	for	for	ADP
fnp-3326	523	31	parkinson	parkinson	NOUN
fnp-3326	523	32	’s	’s	PART
fnp-3326	523	33	disease	disease	NOUN
fnp-3326	523	34	-	-	PUNCT
fnp-3326	523	35	related	relate	VERB
fnp-3326	523	36	brain	brain	NOUN
fnp-3326	523	37	pathology	pathology	NOUN
fnp-3326	523	38	.	.	PUNCT
fnp-3326	524	1	neurosci	neurosci	PROPN
fnp-3326	524	2	lett	lett	PROPN
fnp-3326	524	3	.	.	PUNCT
fnp-3326	525	1	2006;396:67–72	2006;396:67–72	NUM
fnp-3326	525	2	.	.	PROPN
fnp-3326	526	1	14	14	NUM
fnp-3326	526	2	.	.	PUNCT
fnp-3326	526	3	phillips	phillips	PROPN
fnp-3326	526	4	rj	rj	PROPN
fnp-3326	526	5	,	,	PUNCT
fnp-3326	526	6	walter	walter	PROPN
fnp-3326	526	7	gc	gc	PROPN
fnp-3326	526	8	,	,	PUNCT
fnp-3326	526	9	wilder	wilder	ADJ
fnp-3326	526	10	sl	sl	NOUN
fnp-3326	526	11	,	,	PUNCT
fnp-3326	526	12	baronowsky	baronowsky	ADJ
fnp-3326	526	13	ea	ea	PROPN
fnp-3326	526	14	,	,	PUNCT
fnp-3326	526	15	powley	powley	VERB
fnp-3326	526	16	tl	tl	PROPN
fnp-3326	526	17	.	.	PUNCT
fnp-3326	526	18	alpha	alpha	PROPN
fnp-3326	526	19	-	-	PUNCT
fnp-3326	526	20	synuclein	synuclein	NOUN
fnp-3326	526	21	-	-	PUNCT
fnp-3326	526	22	immunopositive	immunopositive	ADJ
fnp-3326	526	23	myenteric	myenteric	ADJ
fnp-3326	526	24	neurons	neuron	NOUN
fnp-3326	526	25	and	and	CCONJ
fnp-3326	526	26	vagal	vagal	ADJ
fnp-3326	526	27	preganglionic	preganglionic	ADJ
fnp-3326	526	28	terminals	terminal	NOUN
fnp-3326	526	29	:	:	PUNCT
fnp-3326	526	30	autonomic	autonomic	ADJ
fnp-3326	526	31	pathway	pathway	NOUN
fnp-3326	526	32	implicated	implicate	VERB
fnp-3326	526	33	in	in	ADP
fnp-3326	526	34	parkinson	parkinson	NOUN
fnp-3326	526	35	’s	’s	PART
fnp-3326	526	36	disease	disease	NOUN
fnp-3326	526	37	?	?	PUNCT
fnp-3326	527	1	neuroscience	neuroscience	NOUN
fnp-3326	527	2	.	.	PUNCT
fnp-3326	528	1	2008;153:733–50	2008;153:733–50	NUM
fnp-3326	528	2	.	.	NOUN
fnp-3326	528	3	15	15	NUM
fnp-3326	528	4	.	.	PUNCT
fnp-3326	528	5	holmqvist	holmqvist	PROPN
fnp-3326	528	6	s	s	PROPN
fnp-3326	528	7	,	,	PUNCT
fnp-3326	528	8	chutna	chutna	NOUN
fnp-3326	528	9	o	o	NOUN
fnp-3326	528	10	,	,	PUNCT
fnp-3326	528	11	bousset	bousset	ADJ
fnp-3326	528	12	l	l	NOUN
fnp-3326	528	13	,	,	PUNCT
fnp-3326	528	14	aldrin	aldrin	NOUN
fnp-3326	528	15	-	-	PUNCT
fnp-3326	528	16	kirk	kirk	PROPN
fnp-3326	528	17	p	p	PROPN
fnp-3326	528	18	,	,	PUNCT
fnp-3326	528	19	li	li	PROPN
fnp-3326	528	20	w	w	PROPN
fnp-3326	528	21	,	,	PUNCT
fnp-3326	528	22	björklund	björklund	VERB
fnp-3326	528	23	t	t	PROPN
fnp-3326	528	24	,	,	PUNCT
fnp-3326	528	25	et	et	PROPN
fnp-3326	528	26	al	al	PROPN
fnp-3326	528	27	.	.	PUNCT
fnp-3326	529	1	direct	direct	ADJ
fnp-3326	529	2	evidence	evidence	NOUN
fnp-3326	529	3	of	of	ADP
fnp-3326	529	4	parkinson	parkinson	NOUN
fnp-3326	529	5	pathology	pathology	NOUN
fnp-3326	529	6	spread	spread	VERB
fnp-3326	529	7	from	from	ADP
fnp-3326	529	8	the	the	DET
fnp-3326	529	9	gastrointestinal	gastrointestinal	ADJ
fnp-3326	529	10	tract	tract	NOUN
fnp-3326	529	11	to	to	ADP
fnp-3326	529	12	the	the	DET
fnp-3326	529	13	brain	brain	NOUN
fnp-3326	529	14	in	in	ADP
fnp-3326	529	15	rats	rat	NOUN
fnp-3326	529	16	.	.	PUNCT
fnp-3326	530	1	acta	acta	PROPN
fnp-3326	530	2	neuropathol	neuropathol	PROPN
fnp-3326	530	3	.	.	PUNCT
fnp-3326	531	1	2014;128:805–20	2014;128:805–20	X
fnp-3326	531	2	.	.	PROPN
fnp-3326	531	3	16	16	NUM
fnp-3326	531	4	.	.	PUNCT
fnp-3326	532	1	breid	breid	PROPN
fnp-3326	532	2	s	s	PROPN
fnp-3326	532	3	,	,	PUNCT
fnp-3326	532	4	bernis	bernis	VERB
fnp-3326	532	5	me	i	PRON
fnp-3326	532	6	,	,	PUNCT
fnp-3326	532	7	babila	babila	PROPN
fnp-3326	532	8	jt	jt	PROPN
fnp-3326	532	9	,	,	PUNCT
fnp-3326	532	10	garza	garza	PROPN
fnp-3326	532	11	mc	mc	PROPN
fnp-3326	532	12	,	,	PUNCT
fnp-3326	532	13	wille	wille	PROPN
fnp-3326	532	14	h	h	NOUN
fnp-3326	532	15	,	,	PUNCT
fnp-3326	532	16	tamgüney	tamgüney	PROPN
fnp-3326	532	17	g.	g.	PROPN
fnp-3326	532	18	neuroinvasion	neuroinvasion	PROPN
fnp-3326	532	19	of	of	ADP
fnp-3326	532	20	α	α	PROPN
fnp-3326	532	21	-	-	PUNCT
fnp-3326	532	22	synuclein	synuclein	NOUN
fnp-3326	532	23	prionoids	prionoid	NOUN
fnp-3326	532	24	after	after	ADP
fnp-3326	532	25	intraperitoneal	intraperitoneal	NOUN
fnp-3326	532	26	and	and	CCONJ
fnp-3326	532	27	intraglossal	intraglossal	PROPN
fnp-3326	532	28	inoculation	inoculation	NOUN
fnp-3326	532	29	.	.	PUNCT
fnp-3326	533	1	j	j	PROPN
fnp-3326	533	2	virol	virol	NOUN
fnp-3326	533	3	.	.	PUNCT
fnp-3326	534	1	2016;90:9182–93	2016;90:9182–93	NUM
fnp-3326	534	2	.	.	X
fnp-3326	535	1	17	17	NUM
fnp-3326	535	2	.	.	PUNCT
fnp-3326	536	1	sargent	sargent	PROPN
fnp-3326	536	2	d	d	PROPN
fnp-3326	536	3	,	,	PUNCT
fnp-3326	536	4	verchère	verchère	PROPN
fnp-3326	536	5	j	j	PROPN
fnp-3326	536	6	,	,	PUNCT
fnp-3326	536	7	lazizzera	lazizzera	PROPN
fnp-3326	536	8	c	c	PROPN
fnp-3326	536	9	,	,	PUNCT
fnp-3326	536	10	gaillard	gaillard	PROPN
fnp-3326	536	11	d	d	PROPN
fnp-3326	536	12	,	,	PUNCT
fnp-3326	536	13	lakhdar	lakhdar	PROPN
fnp-3326	536	14	l	l	NOUN
fnp-3326	536	15	,	,	PUNCT
fnp-3326	536	16	streichenberger	streichenberg	ADJ
fnp-3326	536	17	n	n	NOUN
fnp-3326	536	18	,	,	PUNCT
fnp-3326	536	19	et	et	PROPN
fnp-3326	536	20	al	al	PROPN
fnp-3326	536	21	.	.	PUNCT
fnp-3326	537	1	“	"	PUNCT
fnp-3326	537	2	prion	prion	NOUN
fnp-3326	537	3	-	-	PUNCT
fnp-3326	537	4	like	like	ADJ
fnp-3326	537	5	”	"	PUNCT
fnp-3326	537	6	propagation	propagation	NOUN
fnp-3326	537	7	of	of	ADP
fnp-3326	537	8	the	the	DET
fnp-3326	537	9	synucleinopathy	synucleinopathy	NOUN
fnp-3326	537	10	of	of	ADP
fnp-3326	537	11	m83	m83	NOUN
fnp-3326	537	12	transgenic	transgenic	NOUN
fnp-3326	537	13	mice	mouse	NOUN
fnp-3326	537	14	depends	depend	VERB
fnp-3326	537	15	on	on	ADP
fnp-3326	537	16	the	the	DET
fnp-3326	537	17	mouse	mouse	NOUN
fnp-3326	537	18	genotype	genotype	NOUN
fnp-3326	537	19	and	and	CCONJ
fnp-3326	537	20	type	type	NOUN
fnp-3326	537	21	of	of	ADP
fnp-3326	537	22	inoculum	inoculum	NOUN
fnp-3326	537	23	.	.	PUNCT
fnp-3326	538	1	j	j	PROPN
fnp-3326	538	2	neurochem	neurochem	PROPN
fnp-3326	538	3	.	.	PUNCT
fnp-3326	539	1	2017;143:126–35	2017;143:126–35	NUM
fnp-3326	539	2	.	.	PROPN
fnp-3326	539	3	18	18	NUM
fnp-3326	539	4	.	.	PUNCT
fnp-3326	539	5	manfredsson	manfredsson	PROPN
fnp-3326	539	6	fp	fp	PROPN
fnp-3326	539	7	,	,	PUNCT
fnp-3326	539	8	luk	luk	PROPN
fnp-3326	539	9	kc	kc	PROPN
fnp-3326	539	10	,	,	PUNCT
fnp-3326	539	11	benskey	benskey	PROPN
fnp-3326	539	12	mj	mj	PROPN
fnp-3326	539	13	,	,	PUNCT
fnp-3326	539	14	gezer	gezer	VERB
fnp-3326	539	15	a	a	PRON
fnp-3326	539	16	,	,	PUNCT
fnp-3326	539	17	garcia	garcia	PROPN
fnp-3326	539	18	j	j	PROPN
fnp-3326	539	19	,	,	PUNCT
fnp-3326	539	20	kuhn	kuhn	PROPN
fnp-3326	539	21	nc	nc	PROPN
fnp-3326	539	22	,	,	PUNCT
fnp-3326	539	23	et	et	PROPN
fnp-3326	539	24	al	al	PROPN
fnp-3326	539	25	.	.	PROPN
fnp-3326	539	26	induction	induction	NOUN
fnp-3326	539	27	of	of	ADP
fnp-3326	539	28	alpha	alpha	NOUN
fnp-3326	539	29	-	-	PUNCT
fnp-3326	539	30	synuclein	synuclein	NOUN
fnp-3326	539	31	pathology	pathology	NOUN
fnp-3326	539	32	in	in	ADP
fnp-3326	539	33	the	the	DET
fnp-3326	539	34	enteric	enteric	ADJ
fnp-3326	539	35	nervous	nervous	ADJ
fnp-3326	539	36	system	system	NOUN
fnp-3326	539	37	of	of	ADP
fnp-3326	539	38	the	the	DET
fnp-3326	539	39	rat	rat	NOUN
fnp-3326	539	40	and	and	CCONJ
fnp-3326	539	41	non	non	ADJ
fnp-3326	539	42	-	-	ADJ
fnp-3326	539	43	human	human	ADJ
fnp-3326	539	44	primate	primate	NOUN
fnp-3326	539	45	results	result	NOUN
fnp-3326	539	46	in	in	ADP
fnp-3326	539	47	gastrointestinal	gastrointestinal	ADJ
fnp-3326	539	48	dysmotility	dysmotility	NOUN
fnp-3326	539	49	and	and	CCONJ
fnp-3326	539	50	transient	transient	ADJ
fnp-3326	539	51	cns	cns	PROPN
fnp-3326	539	52	pathology	pathology	NOUN
fnp-3326	539	53	.	.	PUNCT
fnp-3326	540	1	neurobiol	neurobiol	PROPN
fnp-3326	540	2	dis	dis	PROPN
fnp-3326	540	3	.	.	PUNCT
fnp-3326	541	1	2018;112:106–18	2018;112:106–18	NUM
fnp-3326	541	2	.	.	NOUN
fnp-3326	541	3	19	19	NUM
fnp-3326	541	4	.	.	X
fnp-3326	541	5	arotcarena	arotcarena	PROPN
fnp-3326	541	6	m	m	PROPN
fnp-3326	541	7	-	-	PUNCT
fnp-3326	541	8	l	l	NOUN
fnp-3326	541	9	,	,	PUNCT
fnp-3326	541	10	dovero	dovero	NOUN
fnp-3326	541	11	s	s	PROPN
fnp-3326	541	12	,	,	PUNCT
fnp-3326	541	13	prigent	prigent	NOUN
fnp-3326	541	14	a	a	PRON
fnp-3326	541	15	,	,	PUNCT
fnp-3326	541	16	bourdenx	bourdenx	PROPN
fnp-3326	541	17	m	m	NOUN
fnp-3326	541	18	,	,	PUNCT
fnp-3326	541	19	camus	camus	PROPN
fnp-3326	541	20	s	s	PROPN
fnp-3326	541	21	,	,	PUNCT
fnp-3326	541	22	porras	porras	PROPN
fnp-3326	541	23	g	g	PROPN
fnp-3326	541	24	,	,	PUNCT
fnp-3326	541	25	et	et	PROPN
fnp-3326	541	26	al	al	PROPN
fnp-3326	541	27	.	.	PUNCT
fnp-3326	542	1	bidirectional	bidirectional	ADJ
fnp-3326	542	2	gut	gut	PROPN
fnp-3326	542	3	-	-	PUNCT
fnp-3326	542	4	to	to	ADP
fnp-3326	542	5	-	-	PUNCT
fnp-3326	542	6	brain	brain	NOUN
fnp-3326	542	7	and	and	CCONJ
fnp-3326	542	8	brain	brain	NOUN
fnp-3326	542	9	-	-	PUNCT
fnp-3326	542	10	to	to	ADP
fnp-3326	542	11	-	-	PUNCT
fnp-3326	542	12	gut	gut	NOUN
fnp-3326	542	13	propagation	propagation	NOUN
fnp-3326	542	14	of	of	ADP
fnp-3326	542	15	synucleinopathy	synucleinopathy	NOUN
fnp-3326	542	16	in	in	ADP
fnp-3326	542	17	non	non	ADJ
fnp-3326	542	18	-	-	ADJ
fnp-3326	542	19	human	human	ADJ
fnp-3326	542	20	primates	primate	NOUN
fnp-3326	542	21	.	.	PUNCT
fnp-3326	543	1	brain	brain	NOUN
fnp-3326	543	2	.	.	PUNCT
fnp-3326	544	1	oxford	oxford	PROPN
fnp-3326	544	2	academic	academic	PROPN
fnp-3326	544	3	;	;	PUNCT
fnp-3326	544	4	2020;143:1462–75	2020;143:1462–75	NUM
fnp-3326	544	5	.	.	X
fnp-3326	545	1	20	20	NUM
fnp-3326	545	2	.	.	PUNCT
fnp-3326	545	3	challis	challi	NOUN
fnp-3326	545	4	c	c	PROPN
fnp-3326	545	5	,	,	PUNCT
fnp-3326	545	6	hori	hori	PROPN
fnp-3326	545	7	a	a	PROPN
fnp-3326	545	8	,	,	PUNCT
fnp-3326	545	9	sampson	sampson	PROPN
fnp-3326	545	10	tr	tr	VERB
fnp-3326	545	11	,	,	PUNCT
fnp-3326	545	12	yoo	yoo	PROPN
fnp-3326	545	13	bb	bb	PROPN
fnp-3326	545	14	,	,	PUNCT
fnp-3326	545	15	challis	challis	PROPN
fnp-3326	545	16	rc	rc	PROPN
fnp-3326	545	17	,	,	PUNCT
fnp-3326	545	18	hamilton	hamilton	PROPN
fnp-3326	545	19	am	am	PROPN
fnp-3326	545	20	,	,	PUNCT
fnp-3326	545	21	et	et	PROPN
fnp-3326	545	22	al	al	PROPN
fnp-3326	545	23	.	.	PUNCT
fnp-3326	546	1	gut	gut	NOUN
fnp-3326	546	2	-	-	PUNCT
fnp-3326	546	3	seeded	seed	VERB
fnp-3326	546	4	α	α	NOUN
fnp-3326	546	5	-	-	PUNCT
fnp-3326	546	6	synuclein	synuclein	NOUN
fnp-3326	546	7	fibrils	fibril	NOUN
fnp-3326	546	8	promote	promote	VERB
fnp-3326	546	9	gut	gut	NOUN
fnp-3326	546	10	dysfunction	dysfunction	NOUN
fnp-3326	546	11	and	and	CCONJ
fnp-3326	546	12	brain	brain	NOUN
fnp-3326	546	13	pathology	pathology	NOUN
fnp-3326	546	14	specifically	specifically	ADV
fnp-3326	546	15	in	in	ADP
fnp-3326	546	16	aged	aged	ADJ
fnp-3326	546	17	mice	mouse	NOUN
fnp-3326	546	18	.	.	PUNCT
fnp-3326	547	1	nature	nature	NOUN
fnp-3326	547	2	neuroscience	neuroscience	NOUN
fnp-3326	547	3	.	.	PUNCT
fnp-3326	548	1	nature	nature	NOUN
fnp-3326	548	2	publishing	publishing	PROPN
fnp-3326	548	3	group	group	NOUN
fnp-3326	548	4	;	;	PUNCT
fnp-3326	548	5	2020;23:327–36	2020;23:327–36	X
fnp-3326	548	6	.	.	PUNCT
fnp-3326	549	1	21	21	NUM
fnp-3326	549	2	.	.	PUNCT
fnp-3326	550	1	bencsik	bencsik	VERB
fnp-3326	550	2	a	a	PRON
fnp-3326	550	3	,	,	PUNCT
fnp-3326	550	4	muselli	muselli	PROPN
fnp-3326	550	5	l	l	NOUN
fnp-3326	550	6	,	,	PUNCT
fnp-3326	550	7	leboidre	leboidre	PROPN
fnp-3326	550	8	m	m	PROPN
fnp-3326	550	9	,	,	PUNCT
fnp-3326	550	10	lakhdar	lakhdar	PROPN
fnp-3326	550	11	l	l	NOUN
fnp-3326	550	12	,	,	PUNCT
fnp-3326	550	13	baron	baron	X
fnp-3326	550	14	t.	t.	PROPN
fnp-3326	550	15	early	early	ADJ
fnp-3326	550	16	and	and	CCONJ
fnp-3326	550	17	persistent	persistent	ADJ
fnp-3326	550	18	expression	expression	NOUN
fnp-3326	550	19	of	of	ADP
fnp-3326	550	20	phosphorylated	phosphorylate	VERB
fnp-3326	550	21	α	α	NOUN
fnp-3326	550	22	-	-	NOUN
fnp-3326	550	23	synuclein	synuclein	NOUN
fnp-3326	550	24	in	in	ADP
fnp-3326	550	25	the	the	DET
fnp-3326	550	26	enteric	enteric	ADJ
fnp-3326	550	27	nervous	nervous	ADJ
fnp-3326	550	28	system	system	NOUN
fnp-3326	550	29	of	of	ADP
fnp-3326	550	30	a53	a53	PROPN
fnp-3326	550	31	t	t	PROPN
fnp-3326	550	32	mutant	mutant	NOUN
fnp-3326	550	33	human	human	ADJ
fnp-3326	550	34	α	α	PROPN
fnp-3326	550	35	-	-	PUNCT
fnp-3326	550	36	synuclein	synuclein	NOUN
fnp-3326	550	37	transgenic	transgenic	NOUN
fnp-3326	550	38	mice	mouse	NOUN
fnp-3326	550	39	.	.	PUNCT
fnp-3326	551	1	journal	journal	PROPN
fnp-3326	551	2	of	of	ADP
fnp-3326	551	3	neuropathology	neuropathology	NOUN
fnp-3326	551	4	&	&	CCONJ
fnp-3326	551	5	experimental	experimental	ADJ
fnp-3326	551	6	neurology	neurology	NOUN
fnp-3326	551	7	.	.	PUNCT
fnp-3326	552	1	2014;73:1144–51	2014;73:1144–51	NUM
fnp-3326	552	2	.	.	PUNCT
fnp-3326	553	1	22	22	NUM
fnp-3326	553	2	.	.	PUNCT
fnp-3326	554	1	stolzenberg	stolzenberg	PROPN
fnp-3326	554	2	e	e	X
fnp-3326	554	3	,	,	PUNCT
fnp-3326	554	4	berry	berry	VERB
fnp-3326	554	5	d	d	PROPN
fnp-3326	554	6	,	,	PUNCT
fnp-3326	554	7	yang	yang	PROPN
fnp-3326	554	8	d	d	PROPN
fnp-3326	554	9	,	,	PUNCT
fnp-3326	554	10	lee	lee	PROPN
fnp-3326	554	11	ey	ey	PROPN
fnp-3326	554	12	,	,	PUNCT
fnp-3326	554	13	kroemer	kroemer	PROPN
fnp-3326	554	14	a	a	PRON
fnp-3326	554	15	,	,	PUNCT
fnp-3326	554	16	kaufman	kaufman	PROPN
fnp-3326	554	17	s	s	PROPN
fnp-3326	554	18	,	,	PUNCT
fnp-3326	554	19	et	et	PROPN
fnp-3326	554	20	al	al	PROPN
fnp-3326	554	21	.	.	PUNCT
fnp-3326	555	1	a	a	DET
fnp-3326	555	2	role	role	NOUN
fnp-3326	555	3	for	for	ADP
fnp-3326	555	4	neuronal	neuronal	ADJ
fnp-3326	555	5	alpha	alpha	NOUN
fnp-3326	555	6	-	-	PUNCT
fnp-3326	555	7	synuclein	synuclein	NOUN
fnp-3326	555	8	in	in	ADP
fnp-3326	555	9	gastrointestinal	gastrointestinal	ADJ
fnp-3326	555	10	immunity	immunity	NOUN
fnp-3326	555	11	.	.	PUNCT
fnp-3326	556	1	jin	jin	NOUN
fnp-3326	556	2	.	.	PUNCT
fnp-3326	557	1	2017;9:456–63	2017;9:456–63	NUM
fnp-3326	557	2	.	.	NOUN
fnp-3326	557	3	23	23	NUM
fnp-3326	557	4	.	.	PUNCT
fnp-3326	558	1	devos	devos	PROPN
fnp-3326	558	2	d	d	PROPN
fnp-3326	558	3	,	,	PUNCT
fnp-3326	558	4	lebouvier	lebouvier	PROPN
fnp-3326	558	5	t	t	PROPN
fnp-3326	558	6	,	,	PUNCT
fnp-3326	558	7	lardeux	lardeux	PROPN
fnp-3326	558	8	b	b	PROPN
fnp-3326	558	9	,	,	PUNCT
fnp-3326	558	10	biraud	biraud	VERB
fnp-3326	558	11	m	m	PRON
fnp-3326	558	12	,	,	PUNCT
fnp-3326	558	13	rouaud	rouaud	VERB
fnp-3326	558	14	t	t	PROPN
fnp-3326	558	15	,	,	PUNCT
fnp-3326	558	16	pouclet	pouclet	PROPN
fnp-3326	558	17	h	h	PROPN
fnp-3326	558	18	,	,	PUNCT
fnp-3326	558	19	et	et	PROPN
fnp-3326	558	20	al	al	PROPN
fnp-3326	558	21	.	.	PUNCT
fnp-3326	559	1	colonic	colonic	ADJ
fnp-3326	559	2	inflammation	inflammation	NOUN
fnp-3326	559	3	in	in	ADP
fnp-3326	559	4	parkinson	parkinson	NOUN
fnp-3326	559	5	’s	’s	PART
fnp-3326	559	6	disease	disease	NOUN
fnp-3326	559	7	.	.	PUNCT
fnp-3326	560	1	neurobiol	neurobiol	PROPN
fnp-3326	560	2	dis	dis	PROPN
fnp-3326	560	3	.	.	PUNCT
fnp-3326	561	1	2013;50:42–8	2013;50:42–8	NUM
fnp-3326	561	2	.	.	PUNCT
fnp-3326	562	1	24	24	NUM
fnp-3326	562	2	.	.	PUNCT
fnp-3326	562	3	mogi	mogi	PROPN
fnp-3326	562	4	m	m	PROPN
fnp-3326	562	5	,	,	PUNCT
fnp-3326	562	6	harada	harada	PROPN
fnp-3326	562	7	m	m	PROPN
fnp-3326	562	8	,	,	PUNCT
fnp-3326	562	9	kondo	kondo	PROPN
fnp-3326	562	10	t	t	PROPN
fnp-3326	562	11	,	,	PUNCT
fnp-3326	562	12	riederer	riederer	NOUN
fnp-3326	562	13	p	p	NOUN
fnp-3326	562	14	,	,	PUNCT
fnp-3326	562	15	inagaki	inagaki	PROPN
fnp-3326	562	16	h	h	PROPN
fnp-3326	562	17	,	,	PUNCT
fnp-3326	562	18	minami	minami	PROPN
fnp-3326	562	19	m	m	PROPN
fnp-3326	562	20	,	,	PUNCT
fnp-3326	562	21	et	et	PROPN
fnp-3326	562	22	al	al	PROPN
fnp-3326	562	23	.	.	PUNCT
fnp-3326	563	1	interleukin-1	interleukin-1	NOUN
fnp-3326	563	2	beta	beta	NOUN
fnp-3326	563	3	,	,	PUNCT
fnp-3326	563	4	interleukin-6	interleukin-6	NOUN
fnp-3326	563	5	,	,	PUNCT
fnp-3326	563	6	epidermal	epidermal	ADJ
fnp-3326	563	7	growth	growth	NOUN
fnp-3326	563	8	factor	factor	NOUN
fnp-3326	563	9	and	and	CCONJ
fnp-3326	563	10	transforming	transform	VERB
fnp-3326	563	11	growth	growth	NOUN
fnp-3326	563	12	factor	factor	NOUN
fnp-3326	563	13	-	-	PUNCT
fnp-3326	563	14	alpha	alpha	NOUN
fnp-3326	563	15	are	be	AUX
fnp-3326	563	16	elevated	elevate	VERB
fnp-3326	563	17	in	in	ADP
fnp-3326	563	18	the	the	DET
fnp-3326	563	19	brain	brain	NOUN
fnp-3326	563	20	from	from	ADP
fnp-3326	563	21	parkinsonian	parkinsonian	ADJ
fnp-3326	563	22	patients	patient	NOUN
fnp-3326	563	23	.	.	PUNCT
fnp-3326	564	1	neurosci	neurosci	PROPN
fnp-3326	564	2	lett	lett	PROPN
fnp-3326	564	3	.	.	PUNCT
fnp-3326	565	1	1994;180:147–50	1994;180:147–50	NUM
fnp-3326	565	2	.	.	PUNCT
fnp-3326	566	1	25	25	NUM
fnp-3326	566	2	.	.	PUNCT
fnp-3326	567	1	brás	brás	PROPN
fnp-3326	567	2	j	j	PROPN
fnp-3326	567	3	,	,	PUNCT
fnp-3326	567	4	guerreiro	guerreiro	PROPN
fnp-3326	567	5	r	r	PROPN
fnp-3326	567	6	,	,	PUNCT
fnp-3326	567	7	hardy	hardy	ADJ
fnp-3326	567	8	j.	j.	PROPN
fnp-3326	567	9	snapshot	snapshot	PROPN
fnp-3326	567	10	:	:	PUNCT
fnp-3326	567	11	genetics	genetic	NOUN
fnp-3326	567	12	of	of	ADP
fnp-3326	567	13	parkinson	parkinson	NOUN
fnp-3326	567	14	’s	’s	PART
fnp-3326	567	15	disease	disease	NOUN
fnp-3326	567	16	.	.	PUNCT
fnp-3326	568	1	cell	cell	NOUN
fnp-3326	568	2	.	.	PUNCT
fnp-3326	569	1	2015;160:570	2015;160:570	NUM
fnp-3326	569	2	-	-	SYM
fnp-3326	569	3	570.e1	570.e1	NUM
fnp-3326	569	4	.	.	PUNCT
fnp-3326	570	1	26	26	NUM
fnp-3326	570	2	.	.	PUNCT
fnp-3326	571	1	reynolds	reynolds	PROPN
fnp-3326	571	2	rh	rh	PROPN
fnp-3326	571	3	,	,	PUNCT
fnp-3326	571	4	botía	botía	PROPN
fnp-3326	571	5	j	j	PROPN
fnp-3326	571	6	,	,	PUNCT
fnp-3326	571	7	nalls	nalls	PROPN
fnp-3326	571	8	ma	ma	PROPN
fnp-3326	571	9	,	,	PUNCT
fnp-3326	571	10	hardy	hardy	PROPN
fnp-3326	571	11	j	j	PROPN
fnp-3326	571	12	,	,	PUNCT
fnp-3326	571	13	taliun	taliun	PROPN
fnp-3326	571	14	sag	sag	NOUN
fnp-3326	571	15	,	,	PUNCT
fnp-3326	571	16	ryten	ryten	ADJ
fnp-3326	571	17	m.	m.	NOUN
fnp-3326	571	18	moving	move	VERB
fnp-3326	571	19	beyond	beyond	ADP
fnp-3326	571	20	neurons	neuron	NOUN
fnp-3326	571	21	:	:	PUNCT
fnp-3326	571	22	the	the	DET
fnp-3326	571	23	role	role	NOUN
fnp-3326	571	24	of	of	ADP
fnp-3326	571	25	cell	cell	NOUN
fnp-3326	571	26	type	type	NOUN
fnp-3326	571	27	-	-	PUNCT
fnp-3326	571	28	specific	specific	ADJ
fnp-3326	571	29	gene	gene	NOUN
fnp-3326	571	30	regulation	regulation	NOUN
fnp-3326	571	31	in	in	ADP
fnp-3326	571	32	parkinson	parkinson	NOUN
fnp-3326	571	33	’s	’s	PART
fnp-3326	571	34	disease	disease	NOUN
fnp-3326	571	35	heritability	heritability	NOUN
fnp-3326	571	36	.	.	PUNCT
fnp-3326	572	1	npj	npj	PROPN
fnp-3326	572	2	parkinson	parkinson	NOUN
fnp-3326	572	3	’s	’s	PART
fnp-3326	572	4	disease	disease	NOUN
fnp-3326	572	5	.	.	PUNCT
fnp-3326	573	1	2019;5:6	2019;5:6	X
fnp-3326	573	2	.	.	X
fnp-3326	574	1	27	27	NUM
fnp-3326	574	2	.	.	PUNCT
fnp-3326	575	1	witoelar	witoelar	PROPN
fnp-3326	575	2	a	a	PRON
fnp-3326	575	3	,	,	PUNCT
fnp-3326	575	4	jansen	jansen	PROPN
fnp-3326	575	5	ie	ie	X
fnp-3326	575	6	,	,	PUNCT
fnp-3326	575	7	wang	wang	PROPN
fnp-3326	575	8	y	y	PROPN
fnp-3326	575	9	,	,	PUNCT
fnp-3326	575	10	desikan	desikan	PROPN
fnp-3326	575	11	rs	rs	NOUN
fnp-3326	575	12	,	,	PUNCT
fnp-3326	575	13	gibbs	gibbs	PROPN
fnp-3326	575	14	jr	jr	PROPN
fnp-3326	575	15	,	,	PUNCT
fnp-3326	575	16	blauwendraat	blauwendraat	PROPN
fnp-3326	576	1	c	c	X
fnp-3326	576	2	,	,	PUNCT
fnp-3326	576	3	et	et	PROPN
fnp-3326	576	4	al	al	PROPN
fnp-3326	576	5	.	.	PUNCT
fnp-3326	576	6	genome	genome	NOUN
fnp-3326	576	7	-	-	PUNCT
fnp-3326	576	8	wide	wide	ADJ
fnp-3326	576	9	pleiotropy	pleiotropy	NOUN
fnp-3326	576	10	between	between	ADP
fnp-3326	576	11	parkinson	parkinson	NOUN
fnp-3326	576	12	disease	disease	NOUN
fnp-3326	576	13	and	and	CCONJ
fnp-3326	576	14	autoimmune	autoimmune	ADJ
fnp-3326	576	15	diseases	disease	NOUN
fnp-3326	576	16	.	.	PUNCT
fnp-3326	577	1	jama	jama	PROPN
fnp-3326	577	2	neurol	neurol	PROPN
fnp-3326	577	3	.	.	PUNCT
fnp-3326	578	1	2017;74:780–92	2017;74:780–92	X
fnp-3326	578	2	.	.	PROPN
fnp-3326	579	1	28	28	NUM
fnp-3326	579	2	.	.	PUNCT
fnp-3326	580	1	foo	foo	PROPN
fnp-3326	580	2	jn	jn	PROPN
fnp-3326	580	3	,	,	PUNCT
fnp-3326	580	4	chung	chung	PROPN
fnp-3326	580	5	sj	sj	PROPN
fnp-3326	580	6	,	,	PUNCT
fnp-3326	580	7	tan	tan	PROPN
fnp-3326	580	8	lc	lc	PROPN
fnp-3326	580	9	,	,	PUNCT
fnp-3326	580	10	liany	liany	ADJ
fnp-3326	580	11	h	h	NOUN
fnp-3326	580	12	,	,	PUNCT
fnp-3326	580	13	ryu	ryu	PROPN
fnp-3326	580	14	h	h	PROPN
fnp-3326	580	15	-	-	PUNCT
fnp-3326	580	16	s	s	NOUN
fnp-3326	580	17	,	,	PUNCT
fnp-3326	580	18	hong	hong	PROPN
fnp-3326	580	19	m	m	PROPN
fnp-3326	580	20	,	,	PUNCT
fnp-3326	580	21	et	et	PROPN
fnp-3326	580	22	al	al	PROPN
fnp-3326	580	23	.	.	PUNCT
fnp-3326	580	24	linking	link	VERB
fnp-3326	580	25	a	a	DET
fnp-3326	580	26	genome	genome	NOUN
fnp-3326	580	27	-	-	PUNCT
fnp-3326	580	28	wide	wide	ADJ
fnp-3326	580	29	association	association	NOUN
fnp-3326	580	30	study	study	NOUN
fnp-3326	580	31	signal	signal	VERB
fnp-3326	580	32	to	to	ADP
fnp-3326	580	33	a	a	DET
fnp-3326	580	34	lrrk2	lrrk2	NOUN
fnp-3326	580	35	coding	code	VERB
fnp-3326	580	36	variant	variant	NOUN
fnp-3326	580	37	in	in	ADP
fnp-3326	580	38	parkinson	parkinson	NOUN
fnp-3326	580	39	’s	’s	PART
fnp-3326	580	40	disease	disease	NOUN
fnp-3326	580	41	.	.	PUNCT
fnp-3326	581	1	mov	mov	NOUN
fnp-3326	581	2	disord	disord	NOUN
fnp-3326	581	3	.	.	PUNCT
fnp-3326	582	1	2016;31:484–7	2016;31:484–7	NUM
fnp-3326	582	2	.	.	NOUN
fnp-3326	583	1	29	29	NUM
fnp-3326	583	2	.	.	PUNCT
fnp-3326	584	1	umeno	umeno	PROPN
fnp-3326	584	2	j	j	PROPN
fnp-3326	584	3	,	,	PUNCT
fnp-3326	584	4	asano	asano	PROPN
fnp-3326	584	5	k	k	PROPN
fnp-3326	584	6	,	,	PUNCT
fnp-3326	584	7	matsushita	matsushita	PROPN
fnp-3326	584	8	t	t	PROPN
fnp-3326	584	9	,	,	PUNCT
fnp-3326	584	10	matsumoto	matsumoto	PROPN
fnp-3326	584	11	t	t	PROPN
fnp-3326	584	12	,	,	PUNCT
fnp-3326	584	13	kiyohara	kiyohara	PROPN
fnp-3326	584	14	y	y	PROPN
fnp-3326	584	15	,	,	PUNCT
fnp-3326	584	16	iida	iida	PROPN
fnp-3326	584	17	m	m	PROPN
fnp-3326	584	18	,	,	PUNCT
fnp-3326	584	19	et	et	PROPN
fnp-3326	584	20	al	al	PROPN
fnp-3326	584	21	.	.	PUNCT
fnp-3326	585	1	meta	meta	VERB
fnp-3326	585	2	-	-	PUNCT
fnp-3326	585	3	analysis	analysis	NOUN
fnp-3326	585	4	of	of	ADP
fnp-3326	585	5	published	publish	VERB
fnp-3326	585	6	studies	study	NOUN
fnp-3326	585	7	identified	identify	VERB
fnp-3326	585	8	eight	eight	NUM
fnp-3326	585	9	additional	additional	ADJ
fnp-3326	585	10	common	common	ADJ
fnp-3326	585	11	susceptibility	susceptibility	NOUN
fnp-3326	585	12	loci	locus	NOUN
fnp-3326	585	13	for	for	ADP
fnp-3326	585	14	crohn	crohn	PROPN
fnp-3326	585	15	’s	’s	PART
fnp-3326	585	16	disease	disease	NOUN
fnp-3326	585	17	and	and	CCONJ
fnp-3326	585	18	ulcerative	ulcerative	ADJ
fnp-3326	585	19	colitis	colitis	NOUN
fnp-3326	585	20	.	.	PUNCT
fnp-3326	586	1	inflamm	inflamm	PROPN
fnp-3326	586	2	bowel	bowel	PROPN
fnp-3326	586	3	dis	dis	PROPN
fnp-3326	586	4	.	.	PUNCT
fnp-3326	587	1	2011;17:2407–15	2011;17:2407–15	NUM
fnp-3326	587	2	.	.	PUNCT
fnp-3326	588	1	30	30	NUM
fnp-3326	588	2	.	.	PUNCT
fnp-3326	589	1	hui	hui	PROPN
fnp-3326	589	2	ky	ky	PROPN
fnp-3326	589	3	,	,	PUNCT
fnp-3326	589	4	fernandez	fernandez	PROPN
fnp-3326	589	5	-	-	PUNCT
fnp-3326	589	6	hernandez	hernandez	PROPN
fnp-3326	589	7	h	h	PROPN
fnp-3326	589	8	,	,	PUNCT
fnp-3326	589	9	hu	hu	PROPN
fnp-3326	589	10	j	j	PROPN
fnp-3326	589	11	,	,	PUNCT
fnp-3326	589	12	schaffner	schaffner	X
fnp-3326	589	13	a	a	PRON
fnp-3326	589	14	,	,	PUNCT
fnp-3326	589	15	pankratz	pankratz	NOUN
fnp-3326	589	16	n	n	CCONJ
fnp-3326	589	17	,	,	PUNCT
fnp-3326	589	18	hsu	hsu	PROPN
fnp-3326	589	19	n	n	PROPN
fnp-3326	589	20	-	-	PUNCT
fnp-3326	589	21	y	y	PROPN
fnp-3326	589	22	,	,	PUNCT
fnp-3326	589	23	et	et	PROPN
fnp-3326	589	24	al	al	PROPN
fnp-3326	589	25	.	.	PUNCT
fnp-3326	589	26	functional	functional	ADJ
fnp-3326	589	27	variants	variant	NOUN
fnp-3326	589	28	in	in	ADP
fnp-3326	589	29	the	the	DET
fnp-3326	589	30	lrrk2	lrrk2	NOUN
fnp-3326	589	31	gene	gene	NOUN
fnp-3326	589	32	confer	confer	NOUN
fnp-3326	589	33	shared	share	VERB
fnp-3326	589	34	effects	effect	NOUN
fnp-3326	589	35	on	on	ADP
fnp-3326	589	36	risk	risk	NOUN
fnp-3326	589	37	for	for	ADP
fnp-3326	589	38	crohn	crohn	PROPN
fnp-3326	589	39	’s	’s	PART
fnp-3326	589	40	disease	disease	NOUN
fnp-3326	589	41	and	and	CCONJ
fnp-3326	589	42	parkinson	parkinson	NOUN
fnp-3326	589	43	’s	’s	PART
fnp-3326	589	44	disease	disease	NOUN
fnp-3326	589	45	.	.	PUNCT
fnp-3326	590	1	science	science	NOUN
fnp-3326	590	2	translational	translational	ADJ
fnp-3326	590	3	medicine	medicine	NOUN
fnp-3326	590	4	.	.	PUNCT
fnp-3326	591	1	2018;10	2018;10	NOUN
fnp-3326	591	2	:	:	PUNCT
fnp-3326	592	1	eaai7795	eaai7795	PROPN
fnp-3326	592	2	.	.	PROPN
fnp-3326	592	3	31	31	NUM
fnp-3326	592	4	.	.	PUNCT
fnp-3326	592	5	gardet	gardet	PROPN
fnp-3326	592	6	a	a	PROPN
fnp-3326	592	7	,	,	PUNCT
fnp-3326	592	8	benita	benita	PROPN
fnp-3326	592	9	y	y	PROPN
fnp-3326	592	10	,	,	PUNCT
fnp-3326	592	11	li	li	PROPN
fnp-3326	592	12	c	c	PROPN
fnp-3326	592	13	,	,	PUNCT
fnp-3326	592	14	sands	sand	NOUN
fnp-3326	592	15	be	be	AUX
fnp-3326	592	16	,	,	PUNCT
fnp-3326	592	17	ballester	ballester	PROPN
fnp-3326	592	18	i	i	PROPN
fnp-3326	592	19	,	,	PUNCT
fnp-3326	592	20	stevens	stevens	PROPN
fnp-3326	592	21	c	c	PROPN
fnp-3326	592	22	,	,	PUNCT
fnp-3326	592	23	et	et	PROPN
fnp-3326	592	24	al	al	PROPN
fnp-3326	592	25	.	.	PROPN
fnp-3326	592	26	lrrk2	lrrk2	PROPN
fnp-3326	592	27	is	be	AUX
fnp-3326	592	28	involved	involve	VERB
fnp-3326	592	29	in	in	ADP
fnp-3326	592	30	the	the	DET
fnp-3326	592	31	ifn	ifn	PROPN
fnp-3326	592	32	-	-	PUNCT
fnp-3326	592	33	gamma	gamma	NOUN
fnp-3326	592	34	response	response	NOUN
fnp-3326	592	35	and	and	CCONJ
fnp-3326	592	36	host	host	NOUN
fnp-3326	592	37	response	response	NOUN
fnp-3326	592	38	to	to	ADP
fnp-3326	592	39	pathogens	pathogen	NOUN
fnp-3326	592	40	.	.	PUNCT
fnp-3326	593	1	j	j	PROPN
fnp-3326	593	2	immunol	immunol	NOUN
fnp-3326	593	3	.	.	PUNCT
fnp-3326	594	1	2010;185:5577–85	2010;185:5577–85	NUM
fnp-3326	594	2	.	.	PUNCT
fnp-3326	595	1	32	32	NUM
fnp-3326	595	2	.	.	PUNCT
fnp-3326	596	1	hakimi	hakimi	PROPN
fnp-3326	596	2	m	m	PROPN
fnp-3326	596	3	,	,	PUNCT
fnp-3326	596	4	selvanantham	selvanantham	PROPN
fnp-3326	596	5	t	t	PROPN
fnp-3326	596	6	,	,	PUNCT
fnp-3326	596	7	swinton	swinton	PROPN
fnp-3326	596	8	e	e	PROPN
fnp-3326	596	9	,	,	PUNCT
fnp-3326	596	10	padmore	padmore	X
fnp-3326	596	11	rf	rf	NOUN
fnp-3326	596	12	,	,	PUNCT
fnp-3326	596	13	tong	tong	PROPN
fnp-3326	596	14	y	y	PROPN
fnp-3326	596	15	,	,	PUNCT
fnp-3326	596	16	kabbach	kabbach	VERB
fnp-3326	596	17	g	g	NOUN
fnp-3326	596	18	,	,	PUNCT
fnp-3326	596	19	et	et	PROPN
fnp-3326	596	20	al	al	PROPN
fnp-3326	596	21	.	.	PROPN
fnp-3326	596	22	parkinson	parkinson	PROPN
fnp-3326	596	23	’s	’s	PART
fnp-3326	596	24	disease	disease	NOUN
fnp-3326	596	25	-	-	PUNCT
fnp-3326	596	26	linked	link	VERB
fnp-3326	596	27	lrrk2	lrrk2	NOUN
fnp-3326	596	28	is	be	AUX
fnp-3326	596	29	expressed	express	VERB
fnp-3326	596	30	in	in	ADP
fnp-3326	596	31	circulating	circulate	VERB
fnp-3326	596	32	and	and	CCONJ
fnp-3326	596	33	tissue	tissue	NOUN
fnp-3326	596	34	immune	immune	ADJ
fnp-3326	596	35	cells	cell	NOUN
fnp-3326	596	36	and	and	CCONJ
fnp-3326	596	37	upregulated	upregulate	VERB
fnp-3326	596	38	following	follow	VERB
fnp-3326	596	39	recognition	recognition	NOUN
fnp-3326	596	40	of	of	ADP
fnp-3326	596	41	microbial	microbial	ADJ
fnp-3326	596	42	structures	structure	NOUN
fnp-3326	596	43	.	.	PUNCT
fnp-3326	597	1	j	j	PROPN
fnp-3326	597	2	neural	neural	ADJ
fnp-3326	597	3	transm	transm	PROPN
fnp-3326	597	4	(	(	PUNCT
fnp-3326	597	5	vienna	vienna	PROPN
fnp-3326	597	6	)	)	PUNCT
fnp-3326	597	7	.	.	PUNCT
fnp-3326	598	1	2011;118:795–808	2011;118:795–808	X
fnp-3326	598	2	.	.	PUNCT
fnp-3326	599	1	33	33	NUM
fnp-3326	599	2	.	.	PUNCT
fnp-3326	600	1	lin	lin	PROPN
fnp-3326	600	2	j	j	PROPN
fnp-3326	600	3	-	-	PROPN
fnp-3326	600	4	c	c	PROPN
fnp-3326	600	5	,	,	PUNCT
fnp-3326	600	6	lin	lin	PROPN
fnp-3326	600	7	c	c	PROPN
fnp-3326	600	8	-	-	PUNCT
fnp-3326	600	9	s	s	PROPN
fnp-3326	600	10	,	,	PUNCT
fnp-3326	600	11	hsu	hsu	PROPN
fnp-3326	600	12	c	c	PROPN
fnp-3326	600	13	-	-	PUNCT
fnp-3326	600	14	w	w	PROPN
fnp-3326	600	15	,	,	PUNCT
fnp-3326	600	16	lin	lin	PROPN
fnp-3326	600	17	c	c	PROPN
fnp-3326	600	18	-	-	PUNCT
fnp-3326	600	19	l	l	NOUN
fnp-3326	600	20	,	,	PUNCT
fnp-3326	600	21	kao	kao	PROPN
fnp-3326	600	22	c	c	PROPN
fnp-3326	600	23	-	-	PUNCT
fnp-3326	600	24	h.	h.	PROPN
fnp-3326	600	25	association	association	PROPN
fnp-3326	600	26	between	between	ADP
fnp-3326	600	27	parkinson	parkinson	NOUN
fnp-3326	600	28	’s	’s	PART
fnp-3326	600	29	disease	disease	NOUN
fnp-3326	600	30	and	and	CCONJ
fnp-3326	600	31	inflammatory	inflammatory	ADJ
fnp-3326	600	32	bowel	bowel	NOUN
fnp-3326	600	33	disease	disease	NOUN
fnp-3326	600	34	:	:	PUNCT
fnp-3326	600	35	a	a	DET
fnp-3326	600	36	nationwide	nationwide	ADJ
fnp-3326	600	37	taiwanese	taiwanese	ADJ
fnp-3326	600	38	retrospective	retrospective	ADJ
fnp-3326	600	39	cohort	cohort	NOUN
fnp-3326	600	40	study	study	NOUN
fnp-3326	600	41	.	.	PUNCT
fnp-3326	601	1	inflamm	inflamm	PROPN
fnp-3326	601	2	bowel	bowel	PROPN
fnp-3326	601	3	dis	dis	PROPN
fnp-3326	601	4	.	.	PUNCT
fnp-3326	602	1	2016;22:1049–55	2016;22:1049–55	X
fnp-3326	602	2	.	.	PUNCT
fnp-3326	603	1	34	34	NUM
fnp-3326	603	2	.	.	PUNCT
fnp-3326	603	3	nerius	nerius	PROPN
fnp-3326	603	4	m	m	PROPN
fnp-3326	603	5	,	,	PUNCT
fnp-3326	603	6	doblhammer	doblhammer	PROPN
fnp-3326	603	7	g	g	PROPN
fnp-3326	603	8	,	,	PUNCT
fnp-3326	603	9	tamgüney	tamgüney	NOUN
fnp-3326	603	10	g.	g.	PROPN
fnp-3326	603	11	gi	gi	PROPN
fnp-3326	603	12	infections	infection	NOUN
fnp-3326	603	13	are	be	AUX
fnp-3326	603	14	associated	associate	VERB
fnp-3326	603	15	with	with	ADP
fnp-3326	603	16	an	an	DET
fnp-3326	603	17	increased	increase	VERB
fnp-3326	603	18	risk	risk	NOUN
fnp-3326	603	19	of	of	ADP
fnp-3326	603	20	parkinson	parkinson	NOUN
fnp-3326	603	21	’s	’s	PART
fnp-3326	603	22	disease	disease	NOUN
fnp-3326	603	23	.	.	PUNCT
fnp-3326	604	1	gut	gut	VERB
fnp-3326	604	2	.	.	PUNCT
fnp-3326	605	1	2019;gutjnl-2019	2019;gutjnl-2019	NUM
fnp-3326	605	2	-	-	SYM
fnp-3326	605	3	318822	318822	NUM
fnp-3326	605	4	.	.	PUNCT
fnp-3326	606	1	35	35	NUM
fnp-3326	606	2	.	.	PUNCT
fnp-3326	607	1	peter	peter	PROPN
fnp-3326	607	2	i	i	PROPN
fnp-3326	607	3	,	,	PUNCT
fnp-3326	607	4	dubinsky	dubinsky	PROPN
fnp-3326	607	5	m	m	PROPN
fnp-3326	607	6	,	,	PUNCT
fnp-3326	607	7	bressman	bressman	PROPN
fnp-3326	607	8	s	s	PROPN
fnp-3326	607	9	,	,	PUNCT
fnp-3326	607	10	park	park	NOUN
fnp-3326	607	11	a	a	NOUN
fnp-3326	607	12	,	,	PUNCT
fnp-3326	607	13	lu	lu	PROPN
fnp-3326	607	14	c	c	NOUN
fnp-3326	607	15	,	,	PUNCT
fnp-3326	607	16	chen	chen	PROPN
fnp-3326	607	17	n	n	CCONJ
fnp-3326	607	18	,	,	PUNCT
fnp-3326	607	19	et	et	PROPN
fnp-3326	607	20	al	al	PROPN
fnp-3326	607	21	.	.	PUNCT
fnp-3326	607	22	anti	anti	ADJ
fnp-3326	607	23	-	-	ADJ
fnp-3326	607	24	tumor	tumor	ADJ
fnp-3326	607	25	necrosis	necrosis	NOUN
fnp-3326	607	26	factor	factor	NOUN
fnp-3326	607	27	therapy	therapy	NOUN
fnp-3326	607	28	and	and	CCONJ
fnp-3326	607	29	incidence	incidence	NOUN
fnp-3326	607	30	of	of	ADP
fnp-3326	607	31	parkinson	parkinson	NOUN
fnp-3326	607	32	disease	disease	NOUN
fnp-3326	607	33	among	among	ADP
fnp-3326	607	34	patients	patient	NOUN
fnp-3326	607	35	with	with	ADP
fnp-3326	607	36	inflammatory	inflammatory	ADJ
fnp-3326	607	37	bowel	bowel	NOUN
fnp-3326	607	38	disease	disease	NOUN
fnp-3326	607	39	.	.	PUNCT
fnp-3326	608	1	jama	jama	PROPN
fnp-3326	608	2	neurol	neurol	PROPN
fnp-3326	608	3	.	.	PUNCT
fnp-3326	609	1	2018;75:939–46	2018;75:939–46	X
fnp-3326	609	2	.	.	PROPN
fnp-3326	610	1	36	36	NUM
fnp-3326	610	2	.	.	PUNCT
fnp-3326	611	1	rolli	rolli	NOUN
fnp-3326	611	2	-	-	PUNCT
fnp-3326	611	3	derkinderen	derkinderen	PROPN
fnp-3326	611	4	m	m	PROPN
fnp-3326	611	5	,	,	PUNCT
fnp-3326	611	6	leclair	leclair	PROPN
fnp-3326	611	7	-	-	PUNCT
fnp-3326	611	8	visonneau	visonneau	PROPN
fnp-3326	611	9	l	l	NOUN
fnp-3326	611	10	,	,	PUNCT
fnp-3326	611	11	bourreille	bourreille	NOUN
fnp-3326	611	12	a	a	PRON
fnp-3326	611	13	,	,	PUNCT
fnp-3326	611	14	coron	coron	PROPN
fnp-3326	611	15	e	e	NOUN
fnp-3326	611	16	,	,	PUNCT
fnp-3326	611	17	neunlist	neunlist	NOUN
fnp-3326	611	18	m	m	PROPN
fnp-3326	611	19	,	,	PUNCT
fnp-3326	611	20	derkinderen	derkinderen	PROPN
fnp-3326	611	21	p.	p.	PROPN
fnp-3326	611	22	is	be	AUX
fnp-3326	611	23	parkinson	parkinson	NOUN
fnp-3326	611	24	’s	’s	PART
fnp-3326	611	25	disease	disease	NOUN
fnp-3326	611	26	a	a	DET
fnp-3326	611	27	chronic	chronic	ADJ
fnp-3326	611	28	low	low	ADJ
fnp-3326	611	29	-	-	PUNCT
fnp-3326	611	30	grade	grade	NOUN
fnp-3326	611	31	inflammatory	inflammatory	ADJ
fnp-3326	611	32	bowel	bowel	NOUN
fnp-3326	611	33	disease	disease	NOUN
fnp-3326	611	34	?	?	PUNCT
fnp-3326	612	1	j	j	PROPN
fnp-3326	612	2	neurol	neurol	NOUN
fnp-3326	612	3	.	.	PUNCT
fnp-3326	613	1	2019;1–7	2019;1–7	NUM
fnp-3326	613	2	.	.	PUNCT
fnp-3326	614	1	37	37	NUM
fnp-3326	614	2	.	.	PUNCT
fnp-3326	615	1	wan	wan	PROPN
fnp-3326	616	1	q	q	PROPN
fnp-3326	616	2	-	-	PROPN
fnp-3326	616	3	y	y	PROPN
fnp-3326	616	4	,	,	PUNCT
fnp-3326	616	5	zhao	zhao	PROPN
fnp-3326	616	6	r	r	PROPN
fnp-3326	616	7	,	,	PUNCT
fnp-3326	616	8	wu	wu	PROPN
fnp-3326	616	9	x	x	PROPN
fnp-3326	616	10	-	-	PUNCT
fnp-3326	616	11	t.	t.	ADJ
fnp-3326	616	12	older	old	ADJ
fnp-3326	616	13	patients	patient	NOUN
fnp-3326	616	14	with	with	ADP
fnp-3326	616	15	ibd	ibd	PROPN
fnp-3326	616	16	might	might	AUX
fnp-3326	616	17	have	have	VERB
fnp-3326	616	18	higher	high	ADJ
fnp-3326	616	19	risk	risk	NOUN
fnp-3326	616	20	of	of	ADP
fnp-3326	616	21	parkinson	parkinson	NOUN
fnp-3326	616	22	’s	’s	PART
fnp-3326	616	23	disease	disease	NOUN
fnp-3326	616	24	.	.	PUNCT
fnp-3326	617	1	gut	gut	VERB
fnp-3326	617	2	.	.	PUNCT
fnp-3326	618	1	2018;gutjnl-2018	2018;gutjnl-2018	NUM
fnp-3326	618	2	-	-	SYM
fnp-3326	618	3	317103	317103	NUM
fnp-3326	618	4	.	.	PUNCT
fnp-3326	619	1	38	38	NUM
fnp-3326	619	2	.	.	PUNCT
fnp-3326	620	1	kishimoto	kishimoto	PROPN
fnp-3326	620	2	y	y	PROPN
fnp-3326	620	3	,	,	PUNCT
fnp-3326	620	4	zhu	zhu	PROPN
fnp-3326	620	5	w	w	PROPN
fnp-3326	620	6	,	,	PUNCT
fnp-3326	620	7	hosoda	hosoda	PROPN
fnp-3326	620	8	w	w	PROPN
fnp-3326	620	9	,	,	PUNCT
fnp-3326	620	10	sen	sen	PROPN
fnp-3326	620	11	jm	jm	PROPN
fnp-3326	620	12	,	,	PUNCT
fnp-3326	620	13	mattson	mattson	PROPN
fnp-3326	620	14	mp	mp	PROPN
fnp-3326	620	15	.	.	PROPN
fnp-3326	620	16	chronic	chronic	ADJ
fnp-3326	620	17	mild	mild	ADJ
fnp-3326	620	18	gut	gut	NOUN
fnp-3326	620	19	inflammation	inflammation	NOUN
fnp-3326	620	20	accelerates	accelerate	VERB
fnp-3326	620	21	brain	brain	NOUN
fnp-3326	620	22	neuropathology	neuropathology	NOUN
fnp-3326	620	23	and	and	CCONJ
fnp-3326	620	24	motor	motor	NOUN
fnp-3326	620	25	dysfunction	dysfunction	NOUN
fnp-3326	620	26	in	in	ADP
fnp-3326	620	27	α	α	NOUN
fnp-3326	620	28	-	-	PUNCT
fnp-3326	620	29	synuclein	synuclein	ADJ
fnp-3326	620	30	mutant	mutant	ADJ
fnp-3326	620	31	mice	mouse	NOUN
fnp-3326	620	32	.	.	PUNCT
fnp-3326	621	1	neuromolecular	neuromolecular	ADJ
fnp-3326	621	2	med	med	PROPN
fnp-3326	621	3	.	.	PUNCT
fnp-3326	622	1	2019;21:239	2019;21:239	X
fnp-3326	622	2	-	-	PUNCT
fnp-3326	622	3	249	249	NUM
fnp-3326	622	4	.	.	NOUN
fnp-3326	623	1	39	39	NUM
fnp-3326	623	2	.	.	PUNCT
fnp-3326	624	1	houser	houser	PROPN
fnp-3326	624	2	mc	mc	PROPN
fnp-3326	624	3	,	,	PUNCT
fnp-3326	624	4	tansey	tansey	NOUN
fnp-3326	624	5	mg	mg	PROPN
fnp-3326	624	6	.	.	PUNCT
fnp-3326	625	1	the	the	DET
fnp-3326	625	2	gut	gut	NOUN
fnp-3326	625	3	-	-	PUNCT
fnp-3326	625	4	brain	brain	NOUN
fnp-3326	625	5	axis	axis	NOUN
fnp-3326	625	6	:	:	PUNCT
fnp-3326	625	7	is	be	AUX
fnp-3326	625	8	intestinal	intestinal	ADJ
fnp-3326	625	9	inflammation	inflammation	NOUN
fnp-3326	625	10	a	a	DET
fnp-3326	625	11	silent	silent	ADJ
fnp-3326	625	12	driver	driver	NOUN
fnp-3326	625	13	of	of	ADP
fnp-3326	625	14	parkinson	parkinson	NOUN
fnp-3326	625	15	’s	’s	PART
fnp-3326	625	16	disease	disease	NOUN
fnp-3326	625	17	pathogenesis	pathogenesis	NOUN
fnp-3326	625	18	?	?	PUNCT
fnp-3326	626	1	npj	npj	PROPN
fnp-3326	626	2	parkinson	parkinson	NOUN
fnp-3326	626	3	’s	’s	PART
fnp-3326	626	4	disease	disease	NOUN
fnp-3326	626	5	.	.	PUNCT
fnp-3326	627	1	2017;3:3	2017;3:3	NUM
fnp-3326	627	2	.	.	PUNCT
fnp-3326	628	1	40	40	NUM
fnp-3326	628	2	.	.	PUNCT
fnp-3326	629	1	joers	joer	NOUN
fnp-3326	629	2	v	v	ADP
fnp-3326	629	3	,	,	PUNCT
fnp-3326	629	4	masilamoni	masilamoni	ADJ
fnp-3326	629	5	g	g	NOUN
fnp-3326	629	6	,	,	PUNCT
fnp-3326	629	7	kempf	kempf	PROPN
fnp-3326	629	8	d	d	PROPN
fnp-3326	629	9	,	,	PUNCT
fnp-3326	629	10	weiss	weiss	PROPN
fnp-3326	629	11	ar	ar	PROPN
fnp-3326	629	12	,	,	PUNCT
fnp-3326	629	13	rotterman	rotterman	PROPN
fnp-3326	629	14	tm	tm	PROPN
fnp-3326	629	15	,	,	PUNCT
fnp-3326	629	16	murray	murray	PROPN
fnp-3326	629	17	b	b	PROPN
fnp-3326	629	18	,	,	PUNCT
fnp-3326	629	19	et	et	PROPN
fnp-3326	629	20	al	al	PROPN
fnp-3326	629	21	.	.	PUNCT
fnp-3326	630	1	microglia	microglia	PROPN
fnp-3326	630	2	,	,	PUNCT
fnp-3326	630	3	inflammation	inflammation	NOUN
fnp-3326	630	4	and	and	CCONJ
fnp-3326	630	5	gut	gut	NOUN
fnp-3326	630	6	microbiota	microbiota	NOUN
fnp-3326	630	7	responses	response	NOUN
fnp-3326	630	8	in	in	ADP
fnp-3326	630	9	a	a	DET
fnp-3326	630	10	progressive	progressive	ADJ
fnp-3326	630	11	monkey	monkey	NOUN
fnp-3326	630	12	model	model	NOUN
fnp-3326	630	13	of	of	ADP
fnp-3326	630	14	parkinson	parkinson	NOUN
fnp-3326	630	15	’s	’s	PART
fnp-3326	630	16	disease	disease	NOUN
fnp-3326	630	17	:	:	PUNCT
fnp-3326	630	18	a	a	DET
fnp-3326	630	19	case	case	NOUN
fnp-3326	630	20	series	series	NOUN
fnp-3326	630	21	.	.	PUNCT
fnp-3326	631	1	neurobiology	neurobiology	NOUN
fnp-3326	631	2	of	of	ADP
fnp-3326	631	3	disease	disease	NOUN
fnp-3326	631	4	.	.	PUNCT
fnp-3326	632	1	2020;144:105027	2020;144:105027	NUM
fnp-3326	632	2	.	.	PUNCT
fnp-3326	633	1	41	41	NUM
fnp-3326	633	2	.	.	PUNCT
fnp-3326	634	1	kahle	kahle	PROPN
fnp-3326	634	2	pj	pj	PROPN
fnp-3326	634	3	,	,	PUNCT
fnp-3326	634	4	neumann	neumann	PROPN
fnp-3326	634	5	m	m	PROPN
fnp-3326	634	6	,	,	PUNCT
fnp-3326	634	7	ozmen	ozmen	PROPN
fnp-3326	634	8	l	l	PROPN
fnp-3326	634	9	,	,	PUNCT
fnp-3326	634	10	muller	muller	PROPN
fnp-3326	634	11	v	v	PROPN
fnp-3326	634	12	,	,	PUNCT
fnp-3326	634	13	jacobsen	jacobsen	PROPN
fnp-3326	634	14	h	h	PROPN
fnp-3326	634	15	,	,	PUNCT
fnp-3326	634	16	schindzielorz	schindzielorz	VERB
fnp-3326	634	17	a	a	PRON
fnp-3326	634	18	,	,	PUNCT
fnp-3326	634	19	et	et	PROPN
fnp-3326	634	20	al	al	PROPN
fnp-3326	634	21	.	.	PROPN
fnp-3326	634	22	subcellular	subcellular	ADJ
fnp-3326	634	23	localization	localization	NOUN
fnp-3326	634	24	of	of	ADP
fnp-3326	634	25	wild	wild	ADJ
fnp-3326	634	26	-	-	PUNCT
fnp-3326	634	27	type	type	NOUN
fnp-3326	634	28	and	and	CCONJ
fnp-3326	634	29	parkinson	parkinson	NOUN
fnp-3326	634	30	’s	’s	PART
fnp-3326	634	31	disease	disease	NOUN
fnp-3326	634	32	-	-	PUNCT
fnp-3326	634	33	associated	associate	VERB
fnp-3326	634	34	mutant	mutant	ADJ
fnp-3326	634	35	alpha	alpha	NOUN
fnp-3326	634	36	-synuclein	-synuclein	PROPN
fnp-3326	634	37	in	in	ADP
fnp-3326	634	38	human	human	ADJ
fnp-3326	634	39	and	and	CCONJ
fnp-3326	634	40	transgenic	transgenic	NOUN
fnp-3326	634	41	mouse	mouse	NOUN
fnp-3326	634	42	brain	brain	NOUN
fnp-3326	634	43	.	.	PUNCT
fnp-3326	635	1	j	j	PROPN
fnp-3326	635	2	neurosci	neurosci	PROPN
fnp-3326	635	3	.	.	PUNCT
fnp-3326	636	1	2000;20:6365–73	2000;20:6365–73	X
fnp-3326	636	2	.	.	X
fnp-3326	637	1	42	42	NUM
fnp-3326	637	2	.	.	PUNCT
fnp-3326	638	1	jung	jung	PROPN
fnp-3326	638	2	s	s	PROPN
fnp-3326	638	3	,	,	PUNCT
fnp-3326	638	4	aliberti	aliberti	PROPN
fnp-3326	638	5	j	j	PROPN
fnp-3326	638	6	,	,	PUNCT
fnp-3326	638	7	graemmel	graemmel	VERB
fnp-3326	638	8	p	p	NOUN
fnp-3326	638	9	,	,	PUNCT
fnp-3326	638	10	sunshine	sunshine	PROPN
fnp-3326	638	11	mj	mj	PROPN
fnp-3326	638	12	,	,	PUNCT
fnp-3326	638	13	kreutzberg	kreutzberg	PROPN
fnp-3326	638	14	gw	gw	PROPN
fnp-3326	638	15	,	,	PUNCT
fnp-3326	638	16	sher	sher	PROPN
fnp-3326	638	17	a	a	PROPN
fnp-3326	638	18	,	,	PUNCT
fnp-3326	638	19	et	et	PROPN
fnp-3326	638	20	al	al	PROPN
fnp-3326	638	21	.	.	PUNCT
fnp-3326	639	1	analysis	analysis	NOUN
fnp-3326	639	2	of	of	ADP
fnp-3326	639	3	fractalkine	fractalkine	NOUN
fnp-3326	639	4	receptor	receptor	NOUN
fnp-3326	639	5	cx(3)cr1	cx(3)cr1	NOUN
fnp-3326	639	6	function	function	NOUN
fnp-3326	639	7	by	by	ADP
fnp-3326	639	8	targeted	target	VERB
fnp-3326	639	9	deletion	deletion	NOUN
fnp-3326	639	10	and	and	CCONJ
fnp-3326	639	11	green	green	ADJ
fnp-3326	639	12	fluorescent	fluorescent	ADJ
fnp-3326	639	13	protein	protein	NOUN
fnp-3326	639	14	reporter	reporter	NOUN
fnp-3326	639	15	gene	gene	NOUN
fnp-3326	639	16	insertion	insertion	NOUN
fnp-3326	639	17	.	.	PUNCT
fnp-3326	640	1	mol	mol	ADP
fnp-3326	640	2	cell	cell	NOUN
fnp-3326	640	3	biol	biol	NOUN
fnp-3326	640	4	.	.	PUNCT
fnp-3326	641	1	2000;20:4106–14	2000;20:4106–14	X
fnp-3326	641	2	.	.	X
fnp-3326	641	3	43	43	NUM
fnp-3326	641	4	.	.	PUNCT
fnp-3326	642	1	kitazawa	kitazawa	PROPN
fnp-3326	642	2	m	m	PROPN
fnp-3326	642	3	,	,	PUNCT
fnp-3326	642	4	oddo	oddo	VERB
fnp-3326	642	5	s	s	PROPN
fnp-3326	642	6	,	,	PUNCT
fnp-3326	642	7	yamasaki	yamasaki	PROPN
fnp-3326	642	8	tr	tr	VERB
fnp-3326	642	9	,	,	PUNCT
fnp-3326	642	10	green	green	PROPN
fnp-3326	642	11	kn	kn	PROPN
fnp-3326	642	12	,	,	PUNCT
fnp-3326	642	13	laferla	laferla	PROPN
fnp-3326	642	14	fm	fm	PROPN
fnp-3326	642	15	.	.	PROPN
fnp-3326	642	16	lipopolysaccharide	lipopolysaccharide	ADV
fnp-3326	642	17	-	-	PUNCT
fnp-3326	642	18	induced	induce	VERB
fnp-3326	642	19	inflammation	inflammation	NOUN
fnp-3326	642	20	exacerbates	exacerbate	VERB
fnp-3326	642	21	tau	tau	PROPN
fnp-3326	642	22	pathology	pathology	NOUN
fnp-3326	642	23	by	by	ADP
fnp-3326	642	24	a	a	DET
fnp-3326	642	25	cyclin	cyclin	NOUN
fnp-3326	642	26	-	-	PUNCT
fnp-3326	642	27	dependent	dependent	ADJ
fnp-3326	642	28	kinase	kinase	NOUN
fnp-3326	642	29	5	5	NUM
fnp-3326	642	30	-	-	PUNCT
fnp-3326	642	31	mediated	mediate	VERB
fnp-3326	642	32	pathway	pathway	NOUN
fnp-3326	642	33	in	in	ADP
fnp-3326	642	34	a	a	DET
fnp-3326	642	35	transgenic	transgenic	NOUN
fnp-3326	642	36	model	model	NOUN
fnp-3326	642	37	of	of	ADP
fnp-3326	642	38	alzheimer	alzheimer	PROPN
fnp-3326	642	39	’s	’s	PART
fnp-3326	642	40	disease	disease	NOUN
fnp-3326	642	41	.	.	PUNCT
fnp-3326	643	1	j	j	PROPN
fnp-3326	643	2	neurosci	neurosci	PROPN
fnp-3326	643	3	.	.	PUNCT
fnp-3326	644	1	2005;25:8843–53	2005;25:8843–53	NUM
fnp-3326	644	2	.	.	PUNCT
fnp-3326	645	1	44	44	NUM
fnp-3326	645	2	.	.	PUNCT
fnp-3326	646	1	schenk	schenk	PROPN
fnp-3326	646	2	m	m	PROPN
fnp-3326	646	3	,	,	PUNCT
fnp-3326	646	4	bouchon	bouchon	PROPN
fnp-3326	646	5	a	a	PROPN
fnp-3326	646	6	,	,	PUNCT
fnp-3326	646	7	seibold	seibold	ADJ
fnp-3326	646	8	f	f	PROPN
fnp-3326	646	9	,	,	PUNCT
fnp-3326	646	10	mueller	mueller	PROPN
fnp-3326	646	11	c.	c.	PROPN
fnp-3326	646	12	trem-1	trem-1	PROPN
fnp-3326	646	13	-	-	PUNCT
fnp-3326	646	14	-expressing	-expresse	VERB
fnp-3326	646	15	intestinal	intestinal	ADJ
fnp-3326	646	16	macrophages	macrophage	NOUN
fnp-3326	646	17	crucially	crucially	ADV
fnp-3326	646	18	amplify	amplify	VERB
fnp-3326	646	19	chronic	chronic	ADJ
fnp-3326	646	20	inflammation	inflammation	NOUN
fnp-3326	646	21	in	in	ADP
fnp-3326	646	22	experimental	experimental	ADJ
fnp-3326	646	23	colitis	colitis	NOUN
fnp-3326	646	24	and	and	CCONJ
fnp-3326	646	25	inflammatory	inflammatory	ADJ
fnp-3326	646	26	bowel	bowel	NOUN
fnp-3326	646	27	diseases	disease	NOUN
fnp-3326	646	28	.	.	PUNCT
fnp-3326	647	1	j	j	PROPN
fnp-3326	647	2	clin	clin	PROPN
fnp-3326	647	3	invest	invest	PROPN
fnp-3326	647	4	.	.	PUNCT
fnp-3326	648	1	2007;117:3097–106	2007;117:3097–106	INTJ
fnp-3326	648	2	.	.	PUNCT
fnp-3326	649	1	45	45	NUM
fnp-3326	649	2	.	.	PUNCT
fnp-3326	650	1	grathwohl	grathwohl	PROPN
fnp-3326	650	2	sa	sa	PROPN
fnp-3326	650	3	,	,	PUNCT
fnp-3326	650	4	kälin	kälin	PROPN
fnp-3326	650	5	re	re	PROPN
fnp-3326	650	6	,	,	PUNCT
fnp-3326	650	7	bolmont	bolmont	PROPN
fnp-3326	650	8	t	t	PROPN
fnp-3326	650	9	,	,	PUNCT
fnp-3326	650	10	prokop	prokop	PROPN
fnp-3326	650	11	s	s	PROPN
fnp-3326	650	12	,	,	PUNCT
fnp-3326	650	13	winkelmann	winkelmann	PROPN
fnp-3326	650	14	g	g	PROPN
fnp-3326	650	15	,	,	PUNCT
fnp-3326	650	16	kaeser	kaeser	PROPN
fnp-3326	650	17	sa	sa	PROPN
fnp-3326	650	18	,	,	PUNCT
fnp-3326	650	19	et	et	PROPN
fnp-3326	650	20	al	al	PROPN
fnp-3326	650	21	.	.	PUNCT
fnp-3326	650	22	formation	formation	NOUN
fnp-3326	650	23	and	and	CCONJ
fnp-3326	650	24	maintenance	maintenance	NOUN
fnp-3326	650	25	of	of	ADP
fnp-3326	650	26	alzheimer	alzheimer	PROPN
fnp-3326	650	27	’s	’s	PART
fnp-3326	650	28	disease	disease	NOUN
fnp-3326	650	29	β	β	NOUN
fnp-3326	650	30	-	-	NOUN
fnp-3326	650	31	amyloid	amyloid	ADJ
fnp-3326	650	32	plaques	plaque	NOUN
fnp-3326	650	33	in	in	ADP
fnp-3326	650	34	the	the	DET
fnp-3326	650	35	absence	absence	NOUN
fnp-3326	650	36	of	of	ADP
fnp-3326	650	37	microglia	microglia	NOUN
fnp-3326	650	38	.	.	PUNCT
fnp-3326	651	1	nat	nat	PROPN
fnp-3326	651	2	neurosci	neurosci	PROPN
fnp-3326	651	3	.	.	PUNCT
fnp-3326	652	1	2009;12:1361–3	2009;12:1361–3	NUM
fnp-3326	652	2	.	.	PUNCT
fnp-3326	653	1	46	46	NUM
fnp-3326	653	2	.	.	PUNCT
fnp-3326	654	1	rey	rey	PROPN
fnp-3326	654	2	nl	nl	PROPN
fnp-3326	654	3	,	,	PUNCT
fnp-3326	654	4	george	george	PROPN
fnp-3326	654	5	s	s	PROPN
fnp-3326	654	6	,	,	PUNCT
fnp-3326	654	7	steiner	steiner	PROPN
fnp-3326	654	8	ja	ja	PROPN
fnp-3326	654	9	,	,	PUNCT
fnp-3326	654	10	madaj	madaj	PROPN
fnp-3326	654	11	z	z	PROPN
fnp-3326	654	12	,	,	PUNCT
fnp-3326	654	13	luk	luk	PROPN
fnp-3326	654	14	kc	kc	PROPN
fnp-3326	654	15	,	,	PUNCT
fnp-3326	654	16	trojanowski	trojanowski	PROPN
fnp-3326	654	17	jq	jq	PROPN
fnp-3326	654	18	,	,	PUNCT
fnp-3326	654	19	et	et	PROPN
fnp-3326	654	20	al	al	PROPN
fnp-3326	654	21	.	.	PROPN
fnp-3326	655	1	spread	spread	NOUN
fnp-3326	655	2	of	of	ADP
fnp-3326	655	3	aggregates	aggregate	NOUN
fnp-3326	655	4	after	after	SCONJ
fnp-3326	655	5	olfactory	olfactory	NOUN
fnp-3326	655	6	bulb	bulb	VERB
fnp-3326	655	7	injection	injection	NOUN
fnp-3326	655	8	of	of	ADP
fnp-3326	655	9	α	α	NOUN
fnp-3326	655	10	-	-	PUNCT
fnp-3326	655	11	synuclein	synuclein	NOUN
fnp-3326	655	12	fibrils	fibril	NOUN
fnp-3326	655	13	is	be	AUX
fnp-3326	655	14	associated	associate	VERB
fnp-3326	655	15	with	with	ADP
fnp-3326	655	16	early	early	ADJ
fnp-3326	655	17	neuronal	neuronal	ADJ
fnp-3326	655	18	loss	loss	NOUN
fnp-3326	655	19	and	and	CCONJ
fnp-3326	655	20	is	be	AUX
fnp-3326	655	21	reduced	reduce	VERB
fnp-3326	655	22	long	long	ADJ
fnp-3326	655	23	term	term	NOUN
fnp-3326	655	24	.	.	PUNCT
fnp-3326	656	1	acta	acta	PROPN
fnp-3326	656	2	neuropathol	neuropathol	PROPN
fnp-3326	656	3	.	.	PUNCT
fnp-3326	657	1	2017;1–19	2017;1–19	NUM
fnp-3326	657	2	.	.	PUNCT
fnp-3326	658	1	47	47	NUM
fnp-3326	658	2	.	.	PUNCT
fnp-3326	659	1	schneider	schneider	PROPN
fnp-3326	659	2	ca	ca	PROPN
fnp-3326	659	3	,	,	PUNCT
fnp-3326	659	4	rasband	rasband	PROPN
fnp-3326	659	5	ws	ws	PROPN
fnp-3326	659	6	,	,	PUNCT
fnp-3326	659	7	eliceiri	eliceiri	PROPN
fnp-3326	659	8	kw	kw	PROPN
fnp-3326	659	9	.	.	PROPN
fnp-3326	660	1	nih	nih	PROPN
fnp-3326	660	2	image	image	PROPN
fnp-3326	660	3	to	to	ADP
fnp-3326	660	4	imagej	imagej	ADV
fnp-3326	660	5	:	:	PUNCT
fnp-3326	660	6	25	25	NUM
fnp-3326	660	7	years	year	NOUN
fnp-3326	660	8	of	of	ADP
fnp-3326	660	9	image	image	NOUN
fnp-3326	660	10	analysis	analysis	NOUN
fnp-3326	660	11	.	.	PUNCT
fnp-3326	661	1	nat	nat	NOUN
fnp-3326	661	2	methods	method	NOUN
fnp-3326	661	3	.	.	PUNCT
fnp-3326	662	1	2012;9:671–5	2012;9:671–5	NOUN
fnp-3326	662	2	.	.	PUNCT
fnp-3326	663	1	48	48	NUM
fnp-3326	663	2	.	.	PUNCT
fnp-3326	664	1	smyth	smyth	PROPN
fnp-3326	664	2	gk	gk	PROPN
fnp-3326	664	3	.	.	PROPN
fnp-3326	664	4	limma	limma	PROPN
fnp-3326	664	5	:	:	PUNCT
fnp-3326	664	6	linear	linear	NOUN
fnp-3326	664	7	models	model	NOUN
fnp-3326	664	8	for	for	ADP
fnp-3326	664	9	microarray	microarray	NOUN
fnp-3326	664	10	data	datum	NOUN
fnp-3326	664	11	.	.	PUNCT
fnp-3326	665	1	in	in	ADP
fnp-3326	665	2	:	:	PUNCT
fnp-3326	665	3	gentleman	gentleman	ADJ
fnp-3326	665	4	r	r	PROPN
fnp-3326	665	5	,	,	PUNCT
fnp-3326	665	6	carey	carey	PROPN
fnp-3326	665	7	vj	vj	PROPN
fnp-3326	665	8	,	,	PUNCT
fnp-3326	665	9	huber	huber	PROPN
fnp-3326	665	10	w	w	PROPN
fnp-3326	665	11	,	,	PUNCT
fnp-3326	665	12	irizarry	irizarry	ADJ
fnp-3326	665	13	ra	ra	PROPN
fnp-3326	665	14	,	,	PUNCT
fnp-3326	665	15	dudoit	dudoit	PROPN
fnp-3326	665	16	s	s	NOUN
fnp-3326	665	17	,	,	PUNCT
fnp-3326	665	18	editors	editor	NOUN
fnp-3326	665	19	.	.	PUNCT
fnp-3326	666	1	bioinformatics	bioinformatic	NOUN
fnp-3326	666	2	and	and	CCONJ
fnp-3326	666	3	computational	computational	ADJ
fnp-3326	666	4	biology	biology	NOUN
fnp-3326	666	5	solutions	solution	NOUN
fnp-3326	666	6	using	use	VERB
fnp-3326	666	7	r	r	NOUN
fnp-3326	666	8	and	and	CCONJ
fnp-3326	666	9	bioconductor	bioconductor	NOUN
fnp-3326	667	1	[	[	X
fnp-3326	667	2	internet	internet	NOUN
fnp-3326	667	3	]	]	PUNCT
fnp-3326	667	4	.	.	PUNCT
fnp-3326	668	1	new	new	PROPN
fnp-3326	668	2	york	york	PROPN
fnp-3326	668	3	,	,	PUNCT
fnp-3326	668	4	ny	ny	PROPN
fnp-3326	668	5	:	:	PUNCT
fnp-3326	668	6	springer	springer	PROPN
fnp-3326	668	7	new	new	PROPN
fnp-3326	668	8	york	york	PROPN
fnp-3326	668	9	;	;	PUNCT
fnp-3326	668	10	2005	2005	NUM
fnp-3326	668	11	[	[	X
fnp-3326	668	12	cited	cite	VERB
fnp-3326	668	13	2019	2019	NUM
fnp-3326	668	14	may	may	AUX
fnp-3326	668	15	1	1	NUM
fnp-3326	668	16	]	]	PUNCT
fnp-3326	668	17	.	.	PUNCT
fnp-3326	669	1	p.	p.	NOUN
fnp-3326	669	2	397–420	397–420	NUM
fnp-3326	669	3	.	.	PUNCT
fnp-3326	670	1	available	available	ADJ
fnp-3326	670	2	from	from	ADP
fnp-3326	670	3	:	:	PUNCT
fnp-3326	670	4	https://doi.org/10.1007/0-387-29362-0_23	https://doi.org/10.1007/0-387-29362-0_23	PROPN
fnp-3326	670	5	49	49	NUM
fnp-3326	670	6	.	.	PUNCT
fnp-3326	671	1	chassaing	chassae	VERB
fnp-3326	671	2	b	b	PROPN
fnp-3326	671	3	,	,	PUNCT
fnp-3326	671	4	aitken	aitken	PROPN
fnp-3326	671	5	jd	jd	PROPN
fnp-3326	671	6	,	,	PUNCT
fnp-3326	671	7	malleshappa	malleshappa	PROPN
fnp-3326	671	8	m	m	PROPN
fnp-3326	671	9	,	,	PUNCT
fnp-3326	671	10	vijay	vijay	NOUN
fnp-3326	671	11	-	-	PUNCT
fnp-3326	671	12	kumar	kumar	PROPN
fnp-3326	671	13	m.	m.	NOUN
fnp-3326	671	14	dextran	dextran	NOUN
fnp-3326	671	15	sulfate	sulfate	NOUN
fnp-3326	671	16	sodium	sodium	NOUN
fnp-3326	671	17	(	(	PUNCT
fnp-3326	671	18	dss)-induced	dss)-induce	VERB
fnp-3326	671	19	colitis	colitis	NOUN
fnp-3326	671	20	in	in	ADP
fnp-3326	671	21	mice	mouse	NOUN
fnp-3326	671	22	.	.	PUNCT
fnp-3326	672	1	curr	curr	PROPN
fnp-3326	672	2	protoc	protoc	PROPN
fnp-3326	672	3	immunol	immunol	NOUN
fnp-3326	672	4	.	.	PUNCT
fnp-3326	673	1	2014;104	2014;104	NUM
fnp-3326	673	2	:	:	PUNCT
fnp-3326	673	3	unit	unit	NOUN
fnp-3326	673	4	15.25	15.25	NUM
fnp-3326	673	5	.	.	PUNCT
fnp-3326	674	1	50	50	NUM
fnp-3326	674	2	.	.	PUNCT
fnp-3326	675	1	weber	weber	PROPN
fnp-3326	675	2	b	b	PROPN
fnp-3326	675	3	,	,	PUNCT
fnp-3326	675	4	saurer	saurer	PROPN
fnp-3326	675	5	l	l	PROPN
fnp-3326	675	6	,	,	PUNCT
fnp-3326	675	7	schenk	schenk	PROPN
fnp-3326	675	8	m	m	PROPN
fnp-3326	675	9	,	,	PUNCT
fnp-3326	675	10	dickgreber	dickgreber	PROPN
fnp-3326	675	11	n	n	PROPN
fnp-3326	675	12	,	,	PUNCT
fnp-3326	675	13	mueller	mueller	PROPN
fnp-3326	675	14	c.	c.	PROPN
fnp-3326	675	15	cx3cr1	cx3cr1	PROPN
fnp-3326	675	16	defines	define	VERB
fnp-3326	675	17	functionally	functionally	ADV
fnp-3326	675	18	distinct	distinct	ADJ
fnp-3326	675	19	intestinal	intestinal	ADJ
fnp-3326	675	20	mononuclear	mononuclear	ADJ
fnp-3326	675	21	phagocyte	phagocyte	NOUN
fnp-3326	675	22	subsets	subset	NOUN
fnp-3326	675	23	which	which	PRON
fnp-3326	675	24	maintain	maintain	VERB
fnp-3326	675	25	their	their	PRON
fnp-3326	675	26	respective	respective	ADJ
fnp-3326	675	27	functions	function	NOUN
fnp-3326	675	28	during	during	ADP
fnp-3326	675	29	homeostatic	homeostatic	ADJ
fnp-3326	675	30	and	and	CCONJ
fnp-3326	675	31	inflammatory	inflammatory	ADJ
fnp-3326	675	32	conditions	condition	NOUN
fnp-3326	675	33	.	.	PUNCT
fnp-3326	676	1	eur	eur	PROPN
fnp-3326	676	2	j	j	PROPN
fnp-3326	676	3	immunol	immunol	NOUN
fnp-3326	676	4	.	.	PUNCT
fnp-3326	677	1	2011;41:773–9	2011;41:773–9	NUM
fnp-3326	677	2	.	.	PUNCT
fnp-3326	678	1	51	51	NUM
fnp-3326	678	2	.	.	PUNCT
fnp-3326	679	1	medina	medina	PROPN
fnp-3326	679	2	-	-	PUNCT
fnp-3326	679	3	contreras	contreras	PROPN
fnp-3326	679	4	o	o	PROPN
fnp-3326	679	5	,	,	PUNCT
fnp-3326	679	6	geem	geem	PROPN
fnp-3326	679	7	d	d	NOUN
fnp-3326	679	8	,	,	PUNCT
fnp-3326	679	9	laur	laur	PROPN
fnp-3326	679	10	o	o	NOUN
fnp-3326	679	11	,	,	PUNCT
fnp-3326	679	12	williams	williams	PROPN
fnp-3326	679	13	ir	ir	PROPN
fnp-3326	679	14	,	,	PUNCT
fnp-3326	679	15	lira	lira	PROPN
fnp-3326	679	16	sa	sa	PROPN
fnp-3326	679	17	,	,	PUNCT
fnp-3326	679	18	nusrat	nusrat	PROPN
fnp-3326	679	19	a	a	PROPN
fnp-3326	679	20	,	,	PUNCT
fnp-3326	679	21	et	et	PROPN
fnp-3326	679	22	al	al	PROPN
fnp-3326	679	23	.	.	PROPN
fnp-3326	679	24	cx3cr1	cx3cr1	PROPN
fnp-3326	679	25	regulates	regulate	VERB
fnp-3326	679	26	intestinal	intestinal	ADJ
fnp-3326	679	27	macrophage	macrophage	ADJ
fnp-3326	679	28	homeostasis	homeostasis	NOUN
fnp-3326	679	29	,	,	PUNCT
fnp-3326	679	30	bacterial	bacterial	ADJ
fnp-3326	679	31	translocation	translocation	NOUN
fnp-3326	679	32	,	,	PUNCT
fnp-3326	679	33	and	and	CCONJ
fnp-3326	679	34	colitogenic	colitogenic	VERB
fnp-3326	679	35	th17	th17	PROPN
fnp-3326	679	36	responses	response	NOUN
fnp-3326	679	37	in	in	ADP
fnp-3326	679	38	mice	mouse	NOUN
fnp-3326	679	39	.	.	PUNCT
fnp-3326	680	1	j	j	PROPN
fnp-3326	680	2	clin	clin	PROPN
fnp-3326	680	3	invest	invest	PROPN
fnp-3326	680	4	.	.	PUNCT
fnp-3326	681	1	2011;121:4787–95	2011;121:4787–95	NOUN
fnp-3326	681	2	.	.	PUNCT
fnp-3326	682	1	52	52	NUM
fnp-3326	682	2	.	.	PUNCT
fnp-3326	683	1	kostadinova	kostadinova	PROPN
fnp-3326	683	2	fi	fi	PROPN
fnp-3326	683	3	,	,	PUNCT
fnp-3326	683	4	baba	baba	PROPN
fnp-3326	683	5	t	t	PROPN
fnp-3326	683	6	,	,	PUNCT
fnp-3326	683	7	ishida	ishida	PROPN
fnp-3326	683	8	y	y	PROPN
fnp-3326	683	9	,	,	PUNCT
fnp-3326	683	10	kondo	kondo	PROPN
fnp-3326	683	11	t	t	PROPN
fnp-3326	683	12	,	,	PUNCT
fnp-3326	683	13	popivanova	popivanova	VERB
fnp-3326	683	14	bk	bk	PROPN
fnp-3326	683	15	,	,	PUNCT
fnp-3326	683	16	mukaida	mukaida	PROPN
fnp-3326	683	17	n.	n.	PROPN
fnp-3326	683	18	crucial	crucial	ADJ
fnp-3326	683	19	involvement	involvement	NOUN
fnp-3326	683	20	of	of	ADP
fnp-3326	683	21	the	the	DET
fnp-3326	683	22	cx3cr1	cx3cr1	NOUN
fnp-3326	683	23	-	-	PUNCT
fnp-3326	683	24	cx3cl1	cx3cl1	ADJ
fnp-3326	683	25	axis	axis	NOUN
fnp-3326	683	26	in	in	ADP
fnp-3326	683	27	dextran	dextran	ADJ
fnp-3326	683	28	sulfate	sulfate	NOUN
fnp-3326	683	29	sodium	sodium	NOUN
fnp-3326	683	30	-	-	PUNCT
fnp-3326	683	31	mediated	mediate	VERB
fnp-3326	683	32	acute	acute	ADJ
fnp-3326	683	33	colitis	colitis	NOUN
fnp-3326	683	34	in	in	ADP
fnp-3326	683	35	mice	mouse	NOUN
fnp-3326	683	36	.	.	PUNCT
fnp-3326	684	1	j	j	PROPN
fnp-3326	684	2	leukoc	leukoc	VERB
fnp-3326	684	3	biol	biol	PROPN
fnp-3326	684	4	.	.	PUNCT
fnp-3326	685	1	2010;88:133–43	2010;88:133–43	X
fnp-3326	685	2	.	.	PUNCT
fnp-3326	686	1	53	53	NUM
fnp-3326	686	2	.	.	PUNCT
fnp-3326	687	1	kang	kang	PROPN
fnp-3326	687	2	s	s	PROPN
fnp-3326	687	3	,	,	PUNCT
fnp-3326	687	4	okuno	okuno	PROPN
fnp-3326	687	5	t	t	PROPN
fnp-3326	687	6	,	,	PUNCT
fnp-3326	687	7	takegahara	takegahara	NOUN
fnp-3326	687	8	n	n	CCONJ
fnp-3326	687	9	,	,	PUNCT
fnp-3326	687	10	takamatsu	takamatsu	NOUN
fnp-3326	687	11	h	h	NOUN
fnp-3326	687	12	,	,	PUNCT
fnp-3326	687	13	nojima	nojima	PROPN
fnp-3326	687	14	s	s	PROPN
fnp-3326	687	15	,	,	PUNCT
fnp-3326	687	16	kimura	kimura	PROPN
fnp-3326	687	17	t	t	PROPN
fnp-3326	687	18	,	,	PUNCT
fnp-3326	687	19	et	et	PROPN
fnp-3326	687	20	al	al	PROPN
fnp-3326	687	21	.	.	PUNCT
fnp-3326	688	1	intestinal	intestinal	ADJ
fnp-3326	688	2	epithelial	epithelial	ADJ
fnp-3326	688	3	cell	cell	NOUN
fnp-3326	688	4	-	-	PUNCT
fnp-3326	688	5	derived	derive	VERB
fnp-3326	688	6	semaphorin	semaphorin	NOUN
fnp-3326	688	7	7a	7a	NUM
fnp-3326	688	8	negatively	negatively	ADV
fnp-3326	688	9	regulates	regulate	VERB
fnp-3326	688	10	development	development	NOUN
fnp-3326	688	11	of	of	ADP
fnp-3326	688	12	colitis	colitis	NOUN
fnp-3326	688	13	via	via	ADP
fnp-3326	688	14	αvβ1	αvβ1	NOUN
fnp-3326	688	15	integrin	integrin	NOUN
fnp-3326	688	16	.	.	PUNCT
fnp-3326	689	1	j	j	PROPN
fnp-3326	689	2	immunol	immunol	NOUN
fnp-3326	689	3	.	.	PUNCT
fnp-3326	690	1	2012;188:1108–16	2012;188:1108–16	NOUN
fnp-3326	690	2	.	.	PUNCT
fnp-3326	691	1	54	54	NUM
fnp-3326	691	2	.	.	PUNCT
fnp-3326	692	1	li	li	PROPN
fnp-3326	692	2	b	b	PROPN
fnp-3326	692	3	,	,	PUNCT
fnp-3326	692	4	alli	alli	PROPN
fnp-3326	692	5	r	r	PROPN
fnp-3326	692	6	,	,	PUNCT
fnp-3326	692	7	vogel	vogel	NOUN
fnp-3326	692	8	p	p	NOUN
fnp-3326	692	9	,	,	PUNCT
fnp-3326	692	10	geiger	geiger	PROPN
fnp-3326	692	11	tl	tl	PROPN
fnp-3326	692	12	.	.	PROPN
fnp-3326	692	13	il-10	il-10	NUM
fnp-3326	692	14	modulates	modulate	VERB
fnp-3326	692	15	dss	dss	NOUN
fnp-3326	692	16	-	-	PUNCT
fnp-3326	692	17	induced	induce	VERB
fnp-3326	692	18	colitis	colitis	NOUN
fnp-3326	692	19	through	through	ADP
fnp-3326	692	20	a	a	DET
fnp-3326	692	21	macrophage	macrophage	NOUN
fnp-3326	692	22	-	-	PUNCT
fnp-3326	692	23	ros	ros	NOUN
fnp-3326	692	24	-	-	PUNCT
fnp-3326	692	25	no	no	NOUN
fnp-3326	692	26	axis	axis	NOUN
fnp-3326	692	27	.	.	PUNCT
fnp-3326	693	1	mucosal	mucosal	ADJ
fnp-3326	693	2	immunol	immunol	NOUN
fnp-3326	693	3	.	.	PUNCT
fnp-3326	694	1	2014;7:869–78	2014;7:869–78	NUM
fnp-3326	694	2	.	.	PUNCT
fnp-3326	695	1	55	55	NUM
fnp-3326	695	2	.	.	PUNCT
fnp-3326	696	1	prigent	prigent	PROPN
fnp-3326	696	2	a	a	PRON
fnp-3326	696	3	,	,	PUNCT
fnp-3326	696	4	lionnet	lionnet	NOUN
fnp-3326	696	5	a	a	NOUN
fnp-3326	696	6	,	,	PUNCT
fnp-3326	696	7	durieu	durieu	NOUN
fnp-3326	696	8	e	e	NOUN
fnp-3326	696	9	,	,	PUNCT
fnp-3326	696	10	chapelet	chapelet	VERB
fnp-3326	696	11	g	g	PROPN
fnp-3326	696	12	,	,	PUNCT
fnp-3326	696	13	bourreille	bourreille	NOUN
fnp-3326	696	14	a	a	PRON
fnp-3326	696	15	,	,	PUNCT
fnp-3326	696	16	neunlist	neunlist	NOUN
fnp-3326	696	17	m	m	PROPN
fnp-3326	696	18	,	,	PUNCT
fnp-3326	696	19	et	et	PROPN
fnp-3326	696	20	al	al	PROPN
fnp-3326	696	21	.	.	PROPN
fnp-3326	696	22	enteric	enteric	ADJ
fnp-3326	696	23	alpha	alpha	NOUN
fnp-3326	696	24	-	-	PUNCT
fnp-3326	696	25	synuclein	synuclein	NOUN
fnp-3326	696	26	expression	expression	NOUN
fnp-3326	696	27	is	be	AUX
fnp-3326	696	28	increased	increase	VERB
fnp-3326	696	29	in	in	ADP
fnp-3326	696	30	crohn	crohn	PROPN
fnp-3326	696	31	’s	’s	PART
fnp-3326	696	32	disease	disease	NOUN
fnp-3326	696	33	.	.	PUNCT
fnp-3326	697	1	acta	acta	PROPN
fnp-3326	697	2	neuropathol	neuropathol	PROPN
fnp-3326	697	3	.	.	PUNCT
fnp-3326	698	1	2019;137:359–61	2019;137:359–61	X
fnp-3326	698	2	.	.	PUNCT
fnp-3326	699	1	56	56	NUM
fnp-3326	699	2	.	.	PUNCT
fnp-3326	699	3	braak	braak	PROPN
fnp-3326	699	4	h	h	PROPN
fnp-3326	699	5	,	,	PUNCT
fnp-3326	699	6	del	del	PROPN
fnp-3326	699	7	tredici	tredici	PROPN
fnp-3326	699	8	k	k	PROPN
fnp-3326	699	9	,	,	PUNCT
fnp-3326	699	10	rüb	rüb	X
fnp-3326	699	11	u	u	NOUN
fnp-3326	699	12	,	,	PUNCT
fnp-3326	699	13	de	de	PROPN
fnp-3326	699	14	vos	vos	PROPN
fnp-3326	699	15	rai	rai	PROPN
fnp-3326	699	16	,	,	PUNCT
fnp-3326	699	17	jansen	jansen	PROPN
fnp-3326	699	18	steur	steur	PROPN
fnp-3326	699	19	enh	enh	PROPN
fnp-3326	699	20	,	,	PUNCT
fnp-3326	699	21	braak	braak	PROPN
fnp-3326	699	22	e.	e.	PROPN
fnp-3326	699	23	staging	staging	NOUN
fnp-3326	699	24	of	of	ADP
fnp-3326	699	25	brain	brain	NOUN
fnp-3326	699	26	pathology	pathology	NOUN
fnp-3326	699	27	related	relate	VERB
fnp-3326	699	28	to	to	ADP
fnp-3326	699	29	sporadic	sporadic	ADJ
fnp-3326	699	30	parkinson	parkinson	NOUN
fnp-3326	699	31	’s	’s	PART
fnp-3326	699	32	disease	disease	NOUN
fnp-3326	699	33	.	.	PUNCT
fnp-3326	700	1	neurobiol	neurobiol	PROPN
fnp-3326	700	2	aging	aging	NOUN
fnp-3326	700	3	.	.	PUNCT
fnp-3326	701	1	2003;24:197–211	2003;24:197–211	NOUN
fnp-3326	701	2	.	.	PUNCT
fnp-3326	702	1	57	57	NUM
fnp-3326	702	2	.	.	PUNCT
fnp-3326	702	3	neumann	neumann	PROPN
fnp-3326	702	4	m	m	PROPN
fnp-3326	702	5	,	,	PUNCT
fnp-3326	702	6	kahle	kahle	PROPN
fnp-3326	702	7	pj	pj	PROPN
fnp-3326	702	8	,	,	PUNCT
fnp-3326	702	9	giasson	giasson	PROPN
fnp-3326	702	10	bi	bi	PROPN
fnp-3326	702	11	,	,	PUNCT
fnp-3326	702	12	ozmen	ozmen	PROPN
fnp-3326	702	13	l	l	NOUN
fnp-3326	702	14	,	,	PUNCT
fnp-3326	702	15	borroni	borroni	PROPN
fnp-3326	702	16	e	e	PROPN
fnp-3326	702	17	,	,	PUNCT
fnp-3326	702	18	spooren	spooren	PROPN
fnp-3326	702	19	w	w	PROPN
fnp-3326	702	20	,	,	PUNCT
fnp-3326	702	21	et	et	PROPN
fnp-3326	702	22	al	al	PROPN
fnp-3326	702	23	.	.	PROPN
fnp-3326	702	24	misfolded	misfolde	VERB
fnp-3326	702	25	proteinase	proteinase	PROPN
fnp-3326	702	26	k	k	NOUN
fnp-3326	702	27	-	-	ADJ
fnp-3326	702	28	resistant	resistant	ADJ
fnp-3326	702	29	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-3326	702	30	alpha	alpha	NOUN
fnp-3326	702	31	-	-	PUNCT
fnp-3326	702	32	synuclein	synuclein	NOUN
fnp-3326	702	33	in	in	ADP
fnp-3326	702	34	aged	aged	ADJ
fnp-3326	702	35	transgenic	transgenic	NOUN
fnp-3326	702	36	mice	mouse	NOUN
fnp-3326	702	37	with	with	ADP
fnp-3326	702	38	locomotor	locomotor	NOUN
fnp-3326	702	39	deterioration	deterioration	NOUN
fnp-3326	702	40	and	and	CCONJ
fnp-3326	702	41	in	in	ADP
fnp-3326	702	42	human	human	ADJ
fnp-3326	702	43	alpha	alpha	NOUN
fnp-3326	702	44	-	-	PUNCT
fnp-3326	702	45	synucleinopathies	synucleinopathie	NOUN
fnp-3326	702	46	.	.	PUNCT
fnp-3326	703	1	j	j	PROPN
fnp-3326	703	2	clin	clin	PROPN
fnp-3326	703	3	invest	invest	PROPN
fnp-3326	703	4	.	.	PUNCT
fnp-3326	704	1	2002;110:1429–39	2002;110:1429–39	X
fnp-3326	704	2	.	.	PUNCT
fnp-3326	705	1	58	58	NUM
fnp-3326	705	2	.	.	PUNCT
fnp-3326	706	1	johnson	johnson	PROPN
fnp-3326	706	2	me	i	PRON
fnp-3326	706	3	,	,	PUNCT
fnp-3326	706	4	stecher	stecher	PROPN
fnp-3326	706	5	b	b	PROPN
fnp-3326	706	6	,	,	PUNCT
fnp-3326	706	7	labrie	labrie	PROPN
fnp-3326	706	8	v	v	PROPN
fnp-3326	706	9	,	,	PUNCT
fnp-3326	706	10	brundin	brundin	ADJ
fnp-3326	706	11	l	l	NOUN
fnp-3326	706	12	,	,	PUNCT
fnp-3326	706	13	brundin	brundin	ADJ
fnp-3326	706	14	p.	p.	NOUN
fnp-3326	706	15	triggers	trigger	NOUN
fnp-3326	706	16	,	,	PUNCT
fnp-3326	706	17	facilitators	facilitator	NOUN
fnp-3326	706	18	,	,	PUNCT
fnp-3326	706	19	and	and	CCONJ
fnp-3326	706	20	aggravators	aggravator	NOUN
fnp-3326	706	21	:	:	PUNCT
fnp-3326	706	22	redefining	redefine	VERB
fnp-3326	706	23	parkinson	parkinson	NOUN
fnp-3326	706	24	’s	’s	PART
fnp-3326	706	25	disease	disease	NOUN
fnp-3326	706	26	pathogenesis	pathogenesis	NOUN
fnp-3326	706	27	.	.	PUNCT
fnp-3326	707	1	trends	trend	NOUN
fnp-3326	707	2	neurosci	neurosci	PROPN
fnp-3326	707	3	.	.	PUNCT
fnp-3326	708	1	2018;s0166	2018;s0166	NUM
fnp-3326	708	2	-	-	SYM
fnp-3326	708	3	2236:30253–4	2236:30253–4	NUM
fnp-3326	708	4	.	.	PUNCT
fnp-3326	709	1	59	59	NUM
fnp-3326	709	2	.	.	PUNCT
fnp-3326	710	1	braak	braak	PROPN
fnp-3326	710	2	h	h	PROPN
fnp-3326	710	3	,	,	PUNCT
fnp-3326	710	4	del	del	PROPN
fnp-3326	710	5	tredici	tredici	PROPN
fnp-3326	710	6	k	k	PROPN
fnp-3326	710	7	,	,	PUNCT
fnp-3326	710	8	bratzke	bratzke	PROPN
fnp-3326	710	9	h	h	PROPN
fnp-3326	710	10	,	,	PUNCT
fnp-3326	710	11	hamm	hamm	PROPN
fnp-3326	710	12	-	-	PUNCT
fnp-3326	710	13	clement	clement	PROPN
fnp-3326	710	14	j	j	PROPN
fnp-3326	710	15	,	,	PUNCT
fnp-3326	710	16	sandmann	sandmann	PROPN
fnp-3326	710	17	-	-	PUNCT
fnp-3326	710	18	keil	keil	PROPN
fnp-3326	710	19	d	d	NOUN
fnp-3326	710	20	,	,	PUNCT
fnp-3326	710	21	rüb	rüb	X
fnp-3326	710	22	u.	u.	NOUN
fnp-3326	710	23	staging	staging	NOUN
fnp-3326	710	24	of	of	ADP
fnp-3326	710	25	the	the	DET
fnp-3326	710	26	intracerebral	intracerebral	ADJ
fnp-3326	710	27	inclusion	inclusion	NOUN
fnp-3326	710	28	body	body	NOUN
fnp-3326	710	29	pathology	pathology	NOUN
fnp-3326	710	30	associated	associate	VERB
fnp-3326	710	31	with	with	ADP
fnp-3326	710	32	idiopathic	idiopathic	ADJ
fnp-3326	710	33	parkinson	parkinson	NOUN
fnp-3326	710	34	’s	’s	PART
fnp-3326	710	35	disease	disease	NOUN
fnp-3326	710	36	(	(	PUNCT
fnp-3326	710	37	preclinical	preclinical	ADJ
fnp-3326	710	38	and	and	CCONJ
fnp-3326	710	39	clinical	clinical	ADJ
fnp-3326	710	40	stages	stage	NOUN
fnp-3326	710	41	)	)	PUNCT
fnp-3326	710	42	.	.	PUNCT
fnp-3326	711	1	j	j	PROPN
fnp-3326	711	2	neurol	neurol	PROPN
fnp-3326	711	3	.	.	PUNCT
fnp-3326	712	1	2002;249	2002;249	NUM
fnp-3326	712	2	suppl	suppl	ADJ
fnp-3326	713	1	3	3	NUM
fnp-3326	713	2	:	:	PUNCT
fnp-3326	713	3	iii/1	iii/1	PROPN
fnp-3326	713	4	-	-	PUNCT
fnp-3326	713	5	5	5	NUM
fnp-3326	713	6	.	.	NOUN
fnp-3326	713	7	60	60	NUM
fnp-3326	713	8	.	.	PUNCT
fnp-3326	714	1	shannon	shannon	PROPN
fnp-3326	714	2	km	km	PROPN
fnp-3326	714	3	,	,	PUNCT
fnp-3326	714	4	keshavarzian	keshavarzian	PROPN
fnp-3326	714	5	a	a	PROPN
fnp-3326	714	6	,	,	PUNCT
fnp-3326	714	7	dodiya	dodiya	PROPN
fnp-3326	714	8	hb	hb	PROPN
fnp-3326	714	9	,	,	PUNCT
fnp-3326	714	10	jakate	jakate	ADJ
fnp-3326	714	11	s	s	PROPN
fnp-3326	714	12	,	,	PUNCT
fnp-3326	714	13	kordower	kordower	PROPN
fnp-3326	714	14	jh	jh	PROPN
fnp-3326	714	15	.	.	PUNCT
fnp-3326	714	16	is	be	AUX
fnp-3326	714	17	alpha	alpha	NOUN
fnp-3326	714	18	-	-	PUNCT
fnp-3326	714	19	synuclein	synuclein	NOUN
fnp-3326	714	20	in	in	ADP
fnp-3326	714	21	the	the	DET
fnp-3326	714	22	colon	colon	NOUN
fnp-3326	714	23	a	a	DET
fnp-3326	714	24	biomarker	biomarker	NOUN
fnp-3326	714	25	for	for	ADP
fnp-3326	714	26	premotor	premotor	ADJ
fnp-3326	714	27	parkinson	parkinson	NOUN
fnp-3326	714	28	’s	’s	PART
fnp-3326	714	29	disease	disease	NOUN
fnp-3326	714	30	?	?	PUNCT
fnp-3326	715	1	evidence	evidence	NOUN
fnp-3326	715	2	from	from	ADP
fnp-3326	715	3	3	3	NUM
fnp-3326	715	4	cases	case	NOUN
fnp-3326	715	5	.	.	PUNCT
fnp-3326	716	1	mov	mov	NOUN
fnp-3326	716	2	disord	disord	NOUN
fnp-3326	716	3	.	.	PUNCT
fnp-3326	717	1	2012;27:716–9	2012;27:716–9	NUM
fnp-3326	717	2	.	.	PUNCT
fnp-3326	718	1	61	61	NUM
fnp-3326	718	2	.	.	PUNCT
fnp-3326	719	1	lebouvier	lebouvier	PROPN
fnp-3326	719	2	t	t	PROPN
fnp-3326	719	3	,	,	PUNCT
fnp-3326	719	4	neunlist	neunlist	PROPN
fnp-3326	719	5	m	m	PROPN
fnp-3326	719	6	,	,	PUNCT
fnp-3326	719	7	bruley	bruley	PROPN
fnp-3326	719	8	des	des	PROPN
fnp-3326	719	9	varannes	varannes	PROPN
fnp-3326	719	10	s	s	PROPN
fnp-3326	719	11	,	,	PUNCT
fnp-3326	719	12	coron	coron	PROPN
fnp-3326	719	13	e	e	NOUN
fnp-3326	719	14	,	,	PUNCT
fnp-3326	719	15	drouard	drouard	VERB
fnp-3326	719	16	a	a	PRON
fnp-3326	719	17	,	,	PUNCT
fnp-3326	719	18	n’guyen	n’guyen	PROPN
fnp-3326	719	19	j	j	PROPN
fnp-3326	719	20	-	-	PROPN
fnp-3326	719	21	m	m	PROPN
fnp-3326	719	22	,	,	PUNCT
fnp-3326	719	23	et	et	PROPN
fnp-3326	719	24	al	al	PROPN
fnp-3326	719	25	.	.	PUNCT
fnp-3326	720	1	colonic	colonic	NOUN
fnp-3326	720	2	biopsies	biopsy	NOUN
fnp-3326	720	3	to	to	PART
fnp-3326	720	4	assess	assess	VERB
fnp-3326	720	5	the	the	DET
fnp-3326	720	6	neuropathology	neuropathology	NOUN
fnp-3326	720	7	of	of	ADP
fnp-3326	720	8	parkinson	parkinson	NOUN
fnp-3326	720	9	’s	’s	PART
fnp-3326	720	10	disease	disease	NOUN
fnp-3326	720	11	and	and	CCONJ
fnp-3326	720	12	its	its	PRON
fnp-3326	720	13	relationship	relationship	NOUN
fnp-3326	720	14	with	with	ADP
fnp-3326	720	15	symptoms	symptom	NOUN
fnp-3326	720	16	.	.	PUNCT
fnp-3326	721	1	plos	plos	PROPN
fnp-3326	721	2	one	one	NUM
fnp-3326	721	3	.	.	PUNCT
fnp-3326	722	1	2010;5	2010;5	NUM
fnp-3326	722	2	:	:	PUNCT
fnp-3326	722	3	e12728	e12728	NOUN
fnp-3326	722	4	.	.	PUNCT
fnp-3326	723	1	62	62	NUM
fnp-3326	723	2	.	.	PUNCT
fnp-3326	724	1	killinger	killinger	PROPN
fnp-3326	724	2	ba	ba	PROPN
fnp-3326	724	3	,	,	PUNCT
fnp-3326	724	4	madaj	madaj	VERB
fnp-3326	724	5	z	z	PROPN
fnp-3326	724	6	,	,	PUNCT
fnp-3326	724	7	sikora	sikora	PROPN
fnp-3326	724	8	jw	jw	PROPN
fnp-3326	724	9	,	,	PUNCT
fnp-3326	724	10	rey	rey	PROPN
fnp-3326	724	11	n	n	PROPN
fnp-3326	724	12	,	,	PUNCT
fnp-3326	724	13	haas	haas	PROPN
fnp-3326	724	14	aj	aj	PROPN
fnp-3326	724	15	,	,	PUNCT
fnp-3326	724	16	vepa	vepa	PROPN
fnp-3326	724	17	y	y	PROPN
fnp-3326	724	18	,	,	PUNCT
fnp-3326	724	19	et	et	PROPN
fnp-3326	724	20	al	al	PROPN
fnp-3326	724	21	.	.	PUNCT
fnp-3326	725	1	the	the	DET
fnp-3326	725	2	vermiform	vermiform	ADJ
fnp-3326	725	3	appendix	appendix	NOUN
fnp-3326	725	4	impacts	impact	VERB
fnp-3326	725	5	the	the	DET
fnp-3326	725	6	risk	risk	NOUN
fnp-3326	725	7	of	of	ADP
fnp-3326	725	8	developing	develop	VERB
fnp-3326	725	9	parkinson	parkinson	NOUN
fnp-3326	725	10	’s	’s	PART
fnp-3326	725	11	disease	disease	NOUN
fnp-3326	725	12	.	.	PUNCT
fnp-3326	726	1	sci	sci	PROPN
fnp-3326	726	2	transl	transl	PROPN
fnp-3326	726	3	med	med	PROPN
fnp-3326	726	4	.	.	PUNCT
fnp-3326	727	1	2018;10	2018;10	NUM
fnp-3326	727	2	:	:	PUNCT
fnp-3326	727	3	eaar5280	eaar5280	PROPN
fnp-3326	727	4	.	.	PROPN
fnp-3326	728	1	63	63	NUM
fnp-3326	728	2	.	.	PUNCT
fnp-3326	728	3	phillips	phillips	PROPN
fnp-3326	728	4	rj	rj	PROPN
fnp-3326	728	5	,	,	PUNCT
fnp-3326	728	6	walter	walter	PROPN
fnp-3326	728	7	gc	gc	PROPN
fnp-3326	728	8	,	,	PUNCT
fnp-3326	728	9	ringer	ringer	NOUN
fnp-3326	728	10	be	be	PROPN
fnp-3326	728	11	,	,	PUNCT
fnp-3326	728	12	higgs	higgs	PROPN
fnp-3326	728	13	km	km	PROPN
fnp-3326	728	14	,	,	PUNCT
fnp-3326	728	15	powley	powley	VERB
fnp-3326	728	16	tl	tl	PROPN
fnp-3326	728	17	.	.	PUNCT
fnp-3326	728	18	alpha	alpha	PROPN
fnp-3326	728	19	-	-	PUNCT
fnp-3326	728	20	synuclein	synuclein	VERB
fnp-3326	728	21	immunopositive	immunopositive	ADJ
fnp-3326	728	22	aggregates	aggregate	NOUN
fnp-3326	728	23	in	in	ADP
fnp-3326	728	24	the	the	DET
fnp-3326	728	25	myenteric	myenteric	ADJ
fnp-3326	728	26	plexus	plexus	NOUN
fnp-3326	728	27	of	of	ADP
fnp-3326	728	28	the	the	DET
fnp-3326	728	29	aging	age	VERB
fnp-3326	728	30	fischer	fischer	NOUN
fnp-3326	728	31	344	344	NUM
fnp-3326	728	32	rat	rat	PROPN
fnp-3326	728	33	.	.	PUNCT
fnp-3326	728	34	exp	exp	NOUN
fnp-3326	728	35	neurol	neurol	NOUN
fnp-3326	728	36	.	.	PUNCT
fnp-3326	729	1	2009;220:109–19	2009;220:109–19	NOUN
fnp-3326	729	2	.	.	PUNCT
fnp-3326	730	1	64	64	NUM
fnp-3326	730	2	.	.	PUNCT
fnp-3326	731	1	van	van	PROPN
fnp-3326	731	2	den	den	PROPN
fnp-3326	731	3	berge	berge	PROPN
fnp-3326	731	4	n	n	PROPN
fnp-3326	731	5	,	,	PUNCT
fnp-3326	731	6	ferreira	ferreira	PROPN
fnp-3326	731	7	n	n	CCONJ
fnp-3326	731	8	,	,	PUNCT
fnp-3326	731	9	mikkelsen	mikkelsen	PROPN
fnp-3326	731	10	tw	tw	PROPN
fnp-3326	731	11	,	,	PUNCT
fnp-3326	731	12	alstrup	alstrup	PROPN
fnp-3326	731	13	ako	ako	PROPN
fnp-3326	731	14	,	,	PUNCT
fnp-3326	731	15	tamgüney	tamgüney	NOUN
fnp-3326	731	16	g	g	PROPN
fnp-3326	731	17	,	,	PUNCT
fnp-3326	731	18	karlsson	karlsson	PROPN
fnp-3326	731	19	p	p	PROPN
fnp-3326	731	20	,	,	PUNCT
fnp-3326	731	21	et	et	PROPN
fnp-3326	731	22	al	al	PROPN
fnp-3326	731	23	.	.	PROPN
fnp-3326	731	24	ageing	age	VERB
fnp-3326	731	25	promotes	promote	VERB
fnp-3326	731	26	pathological	pathological	ADJ
fnp-3326	731	27	alpha	alpha	NOUN
fnp-3326	731	28	-	-	PUNCT
fnp-3326	731	29	synuclein	synuclein	NOUN
fnp-3326	731	30	propagation	propagation	NOUN
fnp-3326	731	31	and	and	CCONJ
fnp-3326	731	32	autonomic	autonomic	ADJ
fnp-3326	731	33	dysfunction	dysfunction	NOUN
fnp-3326	731	34	in	in	ADP
fnp-3326	731	35	wild	wild	ADJ
fnp-3326	731	36	-	-	PUNCT
fnp-3326	731	37	type	type	NOUN
fnp-3326	731	38	rats	rat	NOUN
fnp-3326	731	39	.	.	PUNCT
fnp-3326	732	1	brain	brain	NOUN
fnp-3326	732	2	.	.	PUNCT
fnp-3326	733	1	2021;awab061	2021;awab061	PROPN
fnp-3326	733	2	65	65	NUM
fnp-3326	733	3	.	.	PUNCT
fnp-3326	734	1	kuo	kuo	PROPN
fnp-3326	734	2	y	y	PROPN
fnp-3326	734	3	-	-	PUNCT
fnp-3326	734	4	m	m	PROPN
fnp-3326	734	5	,	,	PUNCT
fnp-3326	734	6	li	li	PROPN
fnp-3326	734	7	z	z	PROPN
fnp-3326	734	8	,	,	PUNCT
fnp-3326	734	9	jiao	jiao	PROPN
fnp-3326	734	10	y	y	PROPN
fnp-3326	734	11	,	,	PUNCT
fnp-3326	734	12	gaborit	gaborit	NOUN
fnp-3326	734	13	n	n	CCONJ
fnp-3326	734	14	,	,	PUNCT
fnp-3326	734	15	pani	pani	PROPN
fnp-3326	734	16	ak	ak	PROPN
fnp-3326	734	17	,	,	PUNCT
fnp-3326	734	18	orrison	orrison	NOUN
fnp-3326	734	19	bm	bm	PROPN
fnp-3326	734	20	,	,	PUNCT
fnp-3326	734	21	et	et	PROPN
fnp-3326	734	22	al	al	PROPN
fnp-3326	734	23	.	.	PROPN
fnp-3326	734	24	extensive	extensive	ADJ
fnp-3326	734	25	enteric	enteric	ADJ
fnp-3326	734	26	nervous	nervous	ADJ
fnp-3326	734	27	system	system	NOUN
fnp-3326	734	28	abnormalities	abnormality	NOUN
fnp-3326	734	29	in	in	ADP
fnp-3326	734	30	mice	mouse	NOUN
fnp-3326	734	31	transgenic	transgenic	NOUN
fnp-3326	734	32	for	for	ADP
fnp-3326	734	33	artificial	artificial	ADJ
fnp-3326	734	34	chromosomes	chromosome	NOUN
fnp-3326	734	35	containing	contain	VERB
fnp-3326	734	36	parkinson	parkinson	NOUN
fnp-3326	734	37	disease	disease	NOUN
fnp-3326	734	38	-	-	PUNCT
fnp-3326	734	39	associated	associate	VERB
fnp-3326	734	40	α	α	NOUN
fnp-3326	734	41	-	-	PUNCT
fnp-3326	734	42	synuclein	synuclein	NOUN
fnp-3326	734	43	gene	gene	NOUN
fnp-3326	734	44	mutations	mutation	NOUN
fnp-3326	734	45	precede	precede	VERB
fnp-3326	734	46	central	central	ADJ
fnp-3326	734	47	nervous	nervous	ADJ
fnp-3326	734	48	system	system	NOUN
fnp-3326	734	49	changes	change	NOUN
fnp-3326	734	50	.	.	PUNCT
fnp-3326	735	1	hum	hum	NOUN
fnp-3326	735	2	mol	mol	ADP
fnp-3326	735	3	genet	genet	NOUN
fnp-3326	735	4	.	.	PUNCT
fnp-3326	736	1	2010;19:1633–50	2010;19:1633–50	NUM
fnp-3326	736	2	.	.	PUNCT
fnp-3326	737	1	66	66	NUM
fnp-3326	737	2	.	.	PUNCT
fnp-3326	738	1	luk	luk	PROPN
fnp-3326	738	2	kc	kc	PROPN
fnp-3326	738	3	,	,	PUNCT
fnp-3326	738	4	kehm	kehm	PROPN
fnp-3326	738	5	v	v	PROPN
fnp-3326	738	6	,	,	PUNCT
fnp-3326	738	7	carroll	carroll	PROPN
fnp-3326	738	8	j	j	PROPN
fnp-3326	738	9	,	,	PUNCT
fnp-3326	738	10	zhang	zhang	PROPN
fnp-3326	738	11	b	b	PROPN
fnp-3326	738	12	,	,	PUNCT
fnp-3326	738	13	o’brien	o’brien	PROPN
fnp-3326	738	14	p	p	NOUN
fnp-3326	738	15	,	,	PUNCT
fnp-3326	738	16	trojanowski	trojanowski	PROPN
fnp-3326	738	17	jq	jq	PROPN
fnp-3326	738	18	,	,	PUNCT
fnp-3326	738	19	et	et	PROPN
fnp-3326	738	20	al	al	PROPN
fnp-3326	738	21	.	.	PUNCT
fnp-3326	739	1	pathological	pathological	ADJ
fnp-3326	739	2	α	α	NOUN
fnp-3326	739	3	-	-	PUNCT
fnp-3326	739	4	synuclein	synuclein	NOUN
fnp-3326	739	5	transmission	transmission	NOUN
fnp-3326	739	6	initiates	initiate	VERB
fnp-3326	739	7	parkinson	parkinson	NOUN
fnp-3326	739	8	-	-	PUNCT
fnp-3326	739	9	like	like	ADJ
fnp-3326	739	10	neurodegeneration	neurodegeneration	NOUN
fnp-3326	739	11	in	in	ADP
fnp-3326	739	12	nontransgenic	nontransgenic	ADJ
fnp-3326	739	13	mice	mouse	NOUN
fnp-3326	739	14	.	.	PUNCT
fnp-3326	740	1	science	science	NOUN
fnp-3326	740	2	.	.	PUNCT
fnp-3326	741	1	2012;338:949–53	2012;338:949–53	NUM
fnp-3326	741	2	.	.	PUNCT
fnp-3326	742	1	67	67	NUM
fnp-3326	742	2	.	.	PUNCT
fnp-3326	743	1	van	van	PROPN
fnp-3326	743	2	den	den	PROPN
fnp-3326	743	3	berge	berge	PROPN
fnp-3326	743	4	n	n	PROPN
fnp-3326	743	5	,	,	PUNCT
fnp-3326	743	6	ferreira	ferreira	PROPN
fnp-3326	743	7	n	n	CCONJ
fnp-3326	743	8	,	,	PUNCT
fnp-3326	743	9	gram	gram	PROPN
fnp-3326	743	10	h	h	NOUN
fnp-3326	743	11	,	,	PUNCT
fnp-3326	743	12	mikkelsen	mikkelsen	PROPN
fnp-3326	743	13	tw	tw	PROPN
fnp-3326	743	14	,	,	PUNCT
fnp-3326	743	15	alstrup	alstrup	PROPN
fnp-3326	743	16	ako	ako	PROPN
fnp-3326	743	17	,	,	PUNCT
fnp-3326	743	18	casadei	casadei	NOUN
fnp-3326	743	19	n	n	CCONJ
fnp-3326	743	20	,	,	PUNCT
fnp-3326	743	21	et	et	PROPN
fnp-3326	743	22	al	al	PROPN
fnp-3326	743	23	.	.	PROPN
fnp-3326	743	24	evidence	evidence	NOUN
fnp-3326	743	25	for	for	ADP
fnp-3326	743	26	bidirectional	bidirectional	NOUN
fnp-3326	743	27	and	and	CCONJ
fnp-3326	743	28	trans	trans	ADJ
fnp-3326	743	29	-	-	ADJ
fnp-3326	743	30	synaptic	synaptic	ADJ
fnp-3326	743	31	parasympathetic	parasympathetic	NOUN
fnp-3326	743	32	and	and	CCONJ
fnp-3326	743	33	sympathetic	sympathetic	ADJ
fnp-3326	743	34	propagation	propagation	NOUN
fnp-3326	743	35	of	of	ADP
fnp-3326	743	36	alpha	alpha	NOUN
fnp-3326	743	37	-	-	PUNCT
fnp-3326	743	38	synuclein	synuclein	NOUN
fnp-3326	743	39	in	in	ADP
fnp-3326	743	40	rats	rat	NOUN
fnp-3326	743	41	.	.	PUNCT
fnp-3326	744	1	acta	acta	PROPN
fnp-3326	744	2	neuropathol	neuropathol	PROPN
fnp-3326	744	3	.	.	PUNCT
fnp-3326	745	1	2019;138:535	2019;138:535	NUM
fnp-3326	745	2	-	-	SYM
fnp-3326	745	3	550	550	NUM
fnp-3326	745	4	.	.	PUNCT
fnp-3326	746	1	68	68	NUM
fnp-3326	746	2	.	.	PUNCT
fnp-3326	747	1	spillantini	spillantini	PROPN
fnp-3326	747	2	mg	mg	PROPN
fnp-3326	747	3	,	,	PUNCT
fnp-3326	747	4	schmidt	schmidt	PROPN
fnp-3326	747	5	ml	ml	PROPN
fnp-3326	747	6	,	,	PUNCT
fnp-3326	747	7	lee	lee	PROPN
fnp-3326	747	8	vm	vm	PROPN
fnp-3326	747	9	,	,	PUNCT
fnp-3326	747	10	trojanowski	trojanowski	PROPN
fnp-3326	747	11	jq	jq	PROPN
fnp-3326	747	12	,	,	PUNCT
fnp-3326	747	13	jakes	jakes	PROPN
fnp-3326	747	14	r	r	PROPN
fnp-3326	747	15	,	,	PUNCT
fnp-3326	747	16	goedert	goedert	PROPN
fnp-3326	747	17	m.	m.	NOUN
fnp-3326	747	18	alpha	alpha	PROPN
fnp-3326	747	19	-	-	PUNCT
fnp-3326	747	20	synuclein	synuclein	NOUN
fnp-3326	747	21	in	in	ADP
fnp-3326	747	22	lewy	lewy	PROPN
fnp-3326	747	23	bodies	body	NOUN
fnp-3326	747	24	.	.	PUNCT
fnp-3326	748	1	nature	nature	NOUN
fnp-3326	748	2	.	.	PUNCT
fnp-3326	749	1	1997;388:839–40	1997;388:839–40	PROPN
fnp-3326	749	2	.	.	PUNCT
fnp-3326	750	1	69	69	NUM
fnp-3326	750	2	.	.	PUNCT
fnp-3326	751	1	rey	rey	PROPN
fnp-3326	751	2	nl	nl	PROPN
fnp-3326	751	3	,	,	PUNCT
fnp-3326	751	4	steiner	steiner	PROPN
fnp-3326	751	5	ja	ja	PROPN
fnp-3326	751	6	,	,	PUNCT
fnp-3326	751	7	maroof	maroof	PROPN
fnp-3326	751	8	n	n	CCONJ
fnp-3326	751	9	,	,	PUNCT
fnp-3326	751	10	luk	luk	PROPN
fnp-3326	751	11	kc	kc	PROPN
fnp-3326	751	12	,	,	PUNCT
fnp-3326	751	13	madaj	madaj	PROPN
fnp-3326	751	14	z	z	PROPN
fnp-3326	751	15	,	,	PUNCT
fnp-3326	751	16	trojanowski	trojanowski	PROPN
fnp-3326	751	17	jq	jq	PROPN
fnp-3326	751	18	,	,	PUNCT
fnp-3326	751	19	et	et	PROPN
fnp-3326	751	20	al	al	PROPN
fnp-3326	751	21	.	.	PROPN
fnp-3326	752	1	widespread	widespread	ADJ
fnp-3326	752	2	transneuronal	transneuronal	ADJ
fnp-3326	752	3	propagation	propagation	NOUN
fnp-3326	752	4	of	of	ADP
fnp-3326	752	5	α	α	NOUN
fnp-3326	752	6	-	-	PUNCT
fnp-3326	752	7	synucleinopathy	synucleinopathy	NOUN
fnp-3326	752	8	triggered	trigger	VERB
fnp-3326	752	9	in	in	ADP
fnp-3326	752	10	olfactory	olfactory	ADJ
fnp-3326	752	11	bulb	bulb	NOUN
fnp-3326	752	12	mimics	mimic	VERB
fnp-3326	752	13	prodromal	prodromal	ADJ
fnp-3326	752	14	parkinson	parkinson	NOUN
fnp-3326	752	15	’s	’s	PART
fnp-3326	752	16	disease	disease	NOUN
fnp-3326	752	17	.	.	PUNCT
fnp-3326	753	1	j	j	PROPN
fnp-3326	753	2	exp	exp	NOUN
fnp-3326	753	3	med	med	PROPN
fnp-3326	753	4	.	.	PUNCT
fnp-3326	753	5	2016;213:1759–78	2016;213:1759–78	NUM
fnp-3326	753	6	.	.	PUNCT
fnp-3326	754	1	70	70	NUM
fnp-3326	754	2	.	.	PUNCT
fnp-3326	755	1	puntambekar	puntambekar	PROPN
fnp-3326	755	2	ss	ss	PROPN
fnp-3326	755	3	,	,	PUNCT
fnp-3326	755	4	davis	davis	PROPN
fnp-3326	755	5	ds	ds	PROPN
fnp-3326	755	6	,	,	PUNCT
fnp-3326	755	7	hawel	hawel	NOUN
fnp-3326	755	8	l	l	PROPN
fnp-3326	755	9	,	,	PUNCT
fnp-3326	755	10	crane	crane	PROPN
fnp-3326	755	11	j	j	PROPN
fnp-3326	755	12	,	,	PUNCT
fnp-3326	755	13	byus	byus	PROPN
fnp-3326	755	14	cv	cv	PROPN
fnp-3326	755	15	,	,	PUNCT
fnp-3326	755	16	carson	carson	PROPN
fnp-3326	755	17	mj	mj	PROPN
fnp-3326	755	18	.	.	PUNCT
fnp-3326	755	19	lps	lps	PROPN
fnp-3326	755	20	-	-	PUNCT
fnp-3326	755	21	induced	induce	VERB
fnp-3326	755	22	ccl2	ccl2	NOUN
fnp-3326	755	23	expression	expression	NOUN
fnp-3326	755	24	and	and	CCONJ
fnp-3326	755	25	macrophage	macrophage	ADJ
fnp-3326	755	26	influx	influx	NOUN
fnp-3326	755	27	into	into	ADP
fnp-3326	755	28	the	the	DET
fnp-3326	755	29	murine	murine	ADJ
fnp-3326	755	30	central	central	ADJ
fnp-3326	755	31	nervous	nervous	ADJ
fnp-3326	755	32	system	system	NOUN
fnp-3326	755	33	is	be	AUX
fnp-3326	755	34	polyamine	polyamine	NOUN
fnp-3326	755	35	-	-	PUNCT
fnp-3326	755	36	dependent	dependent	ADJ
fnp-3326	755	37	.	.	PUNCT
fnp-3326	756	1	brain	brain	NOUN
fnp-3326	756	2	behav	behav	PROPN
fnp-3326	756	3	immun	immun	PROPN
fnp-3326	756	4	.	.	PUNCT
fnp-3326	757	1	2011;25:629–39	2011;25:629–39	NUM
fnp-3326	757	2	.	.	PUNCT
fnp-3326	758	1	71	71	NUM
fnp-3326	758	2	.	.	PUNCT
fnp-3326	758	3	andus	andus	PROPN
fnp-3326	758	4	t	t	PROPN
fnp-3326	758	5	,	,	PUNCT
fnp-3326	758	6	daig	daig	PROPN
fnp-3326	758	7	r	r	NOUN
fnp-3326	758	8	,	,	PUNCT
fnp-3326	758	9	vogl	vogl	NOUN
fnp-3326	758	10	d	d	NOUN
fnp-3326	758	11	,	,	PUNCT
fnp-3326	758	12	aschenbrenner	aschenbrenner	NOUN
fnp-3326	758	13	e	e	NOUN
fnp-3326	758	14	,	,	PUNCT
fnp-3326	758	15	lock	lock	NOUN
fnp-3326	758	16	g	g	NOUN
fnp-3326	758	17	,	,	PUNCT
fnp-3326	758	18	hollerbach	hollerbach	NOUN
fnp-3326	758	19	s	s	NUM
fnp-3326	758	20	,	,	PUNCT
fnp-3326	758	21	et	et	PROPN
fnp-3326	758	22	al	al	PROPN
fnp-3326	758	23	.	.	PROPN
fnp-3326	758	24	imbalance	imbalance	NOUN
fnp-3326	758	25	of	of	ADP
fnp-3326	758	26	the	the	DET
fnp-3326	758	27	interleukin	interleukin	NOUN
fnp-3326	758	28	1	1	NUM
fnp-3326	758	29	system	system	NOUN
fnp-3326	758	30	in	in	ADP
fnp-3326	758	31	colonic	colonic	ADJ
fnp-3326	758	32	mucosa	mucosa	NOUN
fnp-3326	758	33	—	—	PUNCT
fnp-3326	758	34	association	association	NOUN
fnp-3326	758	35	with	with	ADP
fnp-3326	758	36	intestinal	intestinal	ADJ
fnp-3326	758	37	inflammation	inflammation	NOUN
fnp-3326	758	38	and	and	CCONJ
fnp-3326	758	39	interleukin	interleukin	NOUN
fnp-3326	758	40	1	1	NUM
fnp-3326	758	41	receptor	receptor	NOUN
fnp-3326	758	42	agonist	agonist	NOUN
fnp-3326	758	43	genotype	genotype	NOUN
fnp-3326	758	44	2	2	NUM
fnp-3326	758	45	.	.	PUNCT
fnp-3326	759	1	gut	gut	NOUN
fnp-3326	759	2	.	.	PUNCT
fnp-3326	760	1	1997;41:651–7	1997;41:651–7	NUM
fnp-3326	760	2	.	.	X
fnp-3326	761	1	72	72	NUM
fnp-3326	761	2	.	.	PUNCT
fnp-3326	761	3	sanchez	sanchez	PROPN
fnp-3326	761	4	-	-	PUNCT
fnp-3326	761	5	muñoz	muñoz	PROPN
fnp-3326	761	6	f	f	PROPN
fnp-3326	761	7	,	,	PUNCT
fnp-3326	761	8	dominguez	dominguez	PROPN
fnp-3326	761	9	-	-	PUNCT
fnp-3326	761	10	lopez	lopez	PROPN
fnp-3326	761	11	a	a	PROPN
fnp-3326	761	12	,	,	PUNCT
fnp-3326	761	13	yamamoto	yamamoto	PROPN
fnp-3326	761	14	-	-	PUNCT
fnp-3326	761	15	furusho	furusho	PROPN
fnp-3326	761	16	jk	jk	PROPN
fnp-3326	761	17	.	.	PUNCT
fnp-3326	761	18	role	role	NOUN
fnp-3326	761	19	of	of	ADP
fnp-3326	761	20	cytokines	cytokine	NOUN
fnp-3326	761	21	in	in	ADP
fnp-3326	761	22	inflammatory	inflammatory	ADJ
fnp-3326	761	23	bowel	bowel	NOUN
fnp-3326	761	24	disease	disease	NOUN
fnp-3326	761	25	.	.	PUNCT
fnp-3326	762	1	world	world	PROPN
fnp-3326	762	2	j	j	PROPN
fnp-3326	762	3	gastroenterol	gastroenterol	PROPN
fnp-3326	762	4	.	.	PUNCT
fnp-3326	763	1	2008;14:4280–8	2008;14:4280–8	NOUN
fnp-3326	763	2	.	.	PUNCT
fnp-3326	764	1	73	73	NUM
fnp-3326	764	2	.	.	PUNCT
fnp-3326	765	1	al	al	PROPN
fnp-3326	765	2	-	-	PUNCT
fnp-3326	765	3	sadi	sadi	PROPN
fnp-3326	765	4	rm	rm	PROPN
fnp-3326	765	5	,	,	PUNCT
fnp-3326	765	6	ma	ma	PROPN
fnp-3326	765	7	ty	ty	PROPN
fnp-3326	765	8	.	.	PUNCT
fnp-3326	765	9	il-1beta	il-1beta	PROPN
fnp-3326	765	10	causes	cause	VERB
fnp-3326	765	11	an	an	DET
fnp-3326	765	12	increase	increase	NOUN
fnp-3326	765	13	in	in	ADP
fnp-3326	765	14	intestinal	intestinal	ADJ
fnp-3326	765	15	epithelial	epithelial	ADJ
fnp-3326	765	16	tight	tight	ADJ
fnp-3326	765	17	junction	junction	NOUN
fnp-3326	765	18	permeability	permeability	NOUN
fnp-3326	765	19	.	.	PUNCT
fnp-3326	766	1	j	j	PROPN
fnp-3326	766	2	immunol	immunol	NOUN
fnp-3326	766	3	.	.	PUNCT
fnp-3326	767	1	2007;178:4641–9	2007;178:4641–9	ADJ
fnp-3326	767	2	.	.	PUNCT
fnp-3326	768	1	74	74	NUM
fnp-3326	768	2	.	.	PUNCT
fnp-3326	769	1	capaldo	capaldo	PROPN
fnp-3326	769	2	ct	ct	PROPN
fnp-3326	769	3	,	,	PUNCT
fnp-3326	769	4	nusrat	nusrat	PROPN
fnp-3326	769	5	a.	a.	NOUN
fnp-3326	769	6	cytokine	cytokine	PROPN
fnp-3326	769	7	regulation	regulation	NOUN
fnp-3326	769	8	of	of	ADP
fnp-3326	769	9	tight	tight	ADJ
fnp-3326	769	10	junctions	junction	NOUN
fnp-3326	769	11	.	.	PUNCT
fnp-3326	770	1	biochim	biochim	PROPN
fnp-3326	770	2	biophys	biophy	NOUN
fnp-3326	770	3	acta	acta	PROPN
fnp-3326	770	4	.	.	PUNCT
fnp-3326	771	1	2009;1788:864–71	2009;1788:864–71	NUM
fnp-3326	771	2	.	.	PUNCT
fnp-3326	772	1	75	75	NUM
fnp-3326	772	2	.	.	PUNCT
fnp-3326	773	1	forsyth	forsyth	PROPN
fnp-3326	773	2	cb	cb	PROPN
fnp-3326	773	3	,	,	PUNCT
fnp-3326	773	4	shannon	shannon	PROPN
fnp-3326	773	5	km	km	PROPN
fnp-3326	773	6	,	,	PUNCT
fnp-3326	773	7	kordower	kordower	PROPN
fnp-3326	773	8	jh	jh	PROPN
fnp-3326	773	9	,	,	PUNCT
fnp-3326	773	10	voigt	voigt	PROPN
fnp-3326	773	11	rm	rm	PROPN
fnp-3326	773	12	,	,	PUNCT
fnp-3326	773	13	shaikh	shaikh	PROPN
fnp-3326	773	14	m	m	PROPN
fnp-3326	773	15	,	,	PUNCT
fnp-3326	773	16	jaglin	jaglin	PROPN
fnp-3326	773	17	ja	ja	PROPN
fnp-3326	773	18	,	,	PUNCT
fnp-3326	773	19	et	et	PROPN
fnp-3326	773	20	al	al	PROPN
fnp-3326	773	21	.	.	PROPN
fnp-3326	773	22	increased	increase	VERB
fnp-3326	773	23	intestinal	intestinal	ADJ
fnp-3326	773	24	permeability	permeability	NOUN
fnp-3326	773	25	correlates	correlate	VERB
fnp-3326	773	26	with	with	ADP
fnp-3326	773	27	sigmoid	sigmoid	NOUN
fnp-3326	773	28	mucosa	mucosa	NOUN
fnp-3326	773	29	alpha	alpha	NOUN
fnp-3326	773	30	-	-	PUNCT
fnp-3326	773	31	synuclein	synuclein	NOUN
fnp-3326	773	32	staining	stain	VERB
fnp-3326	773	33	and	and	CCONJ
fnp-3326	773	34	endotoxin	endotoxin	ADJ
fnp-3326	773	35	exposure	exposure	NOUN
fnp-3326	773	36	markers	marker	NOUN
fnp-3326	773	37	in	in	ADP
fnp-3326	773	38	early	early	ADJ
fnp-3326	773	39	parkinson	parkinson	NOUN
fnp-3326	773	40	’s	’s	PART
fnp-3326	773	41	disease	disease	NOUN
fnp-3326	773	42	.	.	PUNCT
fnp-3326	774	1	plos	plos	PROPN
fnp-3326	774	2	one	one	NUM
fnp-3326	774	3	.	.	PUNCT
fnp-3326	775	1	2011;6	2011;6	NUM
fnp-3326	775	2	:	:	PUNCT
fnp-3326	776	1	e28032	e28032	NOUN
fnp-3326	776	2	.	.	PROPN
fnp-3326	777	1	76	76	NUM
fnp-3326	777	2	.	.	PUNCT
fnp-3326	778	1	gray	gray	PROPN
fnp-3326	778	2	mt	mt	PROPN
fnp-3326	778	3	,	,	PUNCT
fnp-3326	778	4	munoz	munoz	PROPN
fnp-3326	778	5	dg	dg	PROPN
fnp-3326	778	6	,	,	PUNCT
fnp-3326	778	7	gray	gray	ADJ
fnp-3326	778	8	da	da	PROPN
fnp-3326	778	9	,	,	PUNCT
fnp-3326	778	10	schlossmacher	schlossmacher	PROPN
fnp-3326	778	11	mg	mg	PROPN
fnp-3326	778	12	,	,	PUNCT
fnp-3326	778	13	woulfe	woulfe	PROPN
fnp-3326	778	14	jm	jm	PROPN
fnp-3326	778	15	.	.	PROPN
fnp-3326	778	16	alpha	alpha	PROPN
fnp-3326	778	17	-	-	PUNCT
fnp-3326	778	18	synuclein	synuclein	NOUN
fnp-3326	778	19	in	in	ADP
fnp-3326	778	20	the	the	DET
fnp-3326	778	21	appendiceal	appendiceal	ADJ
fnp-3326	778	22	mucosa	mucosa	NOUN
fnp-3326	778	23	of	of	ADP
fnp-3326	778	24	neurologically	neurologically	ADV
fnp-3326	778	25	intact	intact	ADJ
fnp-3326	778	26	subjects	subject	NOUN
fnp-3326	778	27	.	.	PUNCT
fnp-3326	779	1	mov	mov	NOUN
fnp-3326	779	2	disord	disord	NOUN
fnp-3326	779	3	.	.	PUNCT
fnp-3326	780	1	2014;29:991–8	2014;29:991–8	NUM
fnp-3326	780	2	.	.	PUNCT
fnp-3326	781	1	77	77	NUM
fnp-3326	781	2	.	.	PUNCT
fnp-3326	782	1	kelly	kelly	PROPN
fnp-3326	782	2	lp	lp	PROPN
fnp-3326	782	3	,	,	PUNCT
fnp-3326	782	4	carvey	carvey	NOUN
fnp-3326	782	5	pm	pm	PROPN
fnp-3326	782	6	,	,	PUNCT
fnp-3326	782	7	keshavarzian	keshavarzian	PROPN
fnp-3326	782	8	a	a	X
fnp-3326	782	9	,	,	PUNCT
fnp-3326	782	10	shannon	shannon	PROPN
fnp-3326	782	11	km	km	PROPN
fnp-3326	782	12	,	,	PUNCT
fnp-3326	782	13	shaikh	shaikh	PROPN
fnp-3326	782	14	m	m	PROPN
fnp-3326	782	15	,	,	PUNCT
fnp-3326	782	16	bakay	bakay	PROPN
fnp-3326	782	17	rae	rae	PROPN
fnp-3326	782	18	,	,	PUNCT
fnp-3326	782	19	et	et	PROPN
fnp-3326	782	20	al	al	PROPN
fnp-3326	782	21	.	.	PROPN
fnp-3326	782	22	progression	progression	NOUN
fnp-3326	782	23	of	of	ADP
fnp-3326	782	24	intestinal	intestinal	ADJ
fnp-3326	782	25	permeability	permeability	NOUN
fnp-3326	782	26	changes	change	NOUN
fnp-3326	782	27	and	and	CCONJ
fnp-3326	782	28	alpha	alpha	NOUN
fnp-3326	782	29	-	-	PUNCT
fnp-3326	782	30	synuclein	synuclein	NOUN
fnp-3326	782	31	expression	expression	NOUN
fnp-3326	782	32	in	in	ADP
fnp-3326	782	33	a	a	DET
fnp-3326	782	34	mouse	mouse	NOUN
fnp-3326	782	35	model	model	NOUN
fnp-3326	782	36	of	of	ADP
fnp-3326	782	37	parkinson	parkinson	NOUN
fnp-3326	782	38	’s	’s	PART
fnp-3326	782	39	disease	disease	NOUN
fnp-3326	782	40	.	.	PUNCT
fnp-3326	783	1	mov	mov	NOUN
fnp-3326	783	2	disord	disord	NOUN
fnp-3326	783	3	.	.	PUNCT
fnp-3326	784	1	2014;29:999–1009	2014;29:999–1009	NUM
fnp-3326	784	2	.	.	X
fnp-3326	784	3	78	78	NUM
fnp-3326	784	4	.	.	PUNCT
fnp-3326	784	5	akarsu	akarsu	PROPN
fnp-3326	784	6	es	es	PROPN
fnp-3326	784	7	,	,	PUNCT
fnp-3326	784	8	mamuk	mamuk	PROPN
fnp-3326	784	9	s.	s.	PROPN
fnp-3326	784	10	escherichia	escherichia	NOUN
fnp-3326	784	11	coli	coli	NOUN
fnp-3326	784	12	lipopolysaccharides	lipopolysaccharide	NOUN
fnp-3326	784	13	produce	produce	VERB
fnp-3326	784	14	serotype	serotype	NOUN
fnp-3326	784	15	-	-	PUNCT
fnp-3326	784	16	specific	specific	ADJ
fnp-3326	784	17	hypothermic	hypothermic	ADJ
fnp-3326	784	18	response	response	NOUN
fnp-3326	784	19	in	in	ADP
fnp-3326	784	20	biotelemetered	biotelemetere	VERB
fnp-3326	784	21	rats	rat	NOUN
fnp-3326	784	22	.	.	PUNCT
fnp-3326	785	1	am	be	AUX
fnp-3326	785	2	j	j	PROPN
fnp-3326	785	3	physiol	physiol	PROPN
fnp-3326	785	4	regul	regul	PROPN
fnp-3326	785	5	integr	integr	PROPN
fnp-3326	785	6	comp	comp	PROPN
fnp-3326	785	7	physiol	physiol	PROPN
fnp-3326	785	8	.	.	PUNCT
fnp-3326	786	1	2007;292	2007;292	NUM
fnp-3326	786	2	:	:	PUNCT
fnp-3326	786	3	r1846	r1846	NOUN
fnp-3326	786	4	-	-	PUNCT
fnp-3326	786	5	1850	1850	NUM
fnp-3326	786	6	.	.	PUNCT
fnp-3326	787	1	79	79	NUM
fnp-3326	787	2	.	.	PUNCT
fnp-3326	788	1	dodiya	dodiya	PROPN
fnp-3326	788	2	hb	hb	PROPN
fnp-3326	788	3	,	,	PUNCT
fnp-3326	788	4	forsyth	forsyth	PROPN
fnp-3326	788	5	cb	cb	PROPN
fnp-3326	788	6	,	,	PUNCT
fnp-3326	788	7	voigt	voigt	PROPN
fnp-3326	788	8	rm	rm	PROPN
fnp-3326	788	9	,	,	PUNCT
fnp-3326	788	10	engen	engen	PROPN
fnp-3326	788	11	pa	pa	PROPN
fnp-3326	788	12	,	,	PUNCT
fnp-3326	788	13	patel	patel	PROPN
fnp-3326	788	14	j	j	PROPN
fnp-3326	788	15	,	,	PUNCT
fnp-3326	788	16	shaikh	shaikh	PROPN
fnp-3326	788	17	m	m	PROPN
fnp-3326	788	18	,	,	PUNCT
fnp-3326	788	19	et	et	PROPN
fnp-3326	788	20	al	al	PROPN
fnp-3326	788	21	.	.	PROPN
fnp-3326	789	1	chronic	chronic	ADJ
fnp-3326	789	2	stress	stress	NOUN
fnp-3326	789	3	-	-	PUNCT
fnp-3326	789	4	induced	induce	VERB
fnp-3326	789	5	gut	gut	NOUN
fnp-3326	789	6	dysfunction	dysfunction	NOUN
fnp-3326	789	7	exacerbates	exacerbate	VERB
fnp-3326	789	8	parkinson	parkinson	NOUN
fnp-3326	789	9	’s	’s	PART
fnp-3326	789	10	disease	disease	NOUN
fnp-3326	789	11	phenotype	phenotype	NOUN
fnp-3326	789	12	and	and	CCONJ
fnp-3326	789	13	pathology	pathology	NOUN
fnp-3326	789	14	in	in	ADP
fnp-3326	789	15	a	a	DET
fnp-3326	789	16	rotenone	rotenone	NOUN
fnp-3326	789	17	-	-	PUNCT
fnp-3326	789	18	induced	induce	VERB
fnp-3326	789	19	mouse	mouse	NOUN
fnp-3326	789	20	model	model	NOUN
fnp-3326	789	21	of	of	ADP
fnp-3326	789	22	parkinson	parkinson	NOUN
fnp-3326	789	23	’s	’s	PART
fnp-3326	789	24	disease	disease	NOUN
fnp-3326	789	25	.	.	PUNCT
fnp-3326	790	1	neurobiol	neurobiol	PROPN
fnp-3326	790	2	dis	dis	PROPN
fnp-3326	790	3	.	.	PUNCT
fnp-3326	791	1	2020;135:104352	2020;135:104352	NUM
fnp-3326	791	2	.	.	PUNCT
fnp-3326	792	1	80	80	NUM
fnp-3326	792	2	.	.	PUNCT
fnp-3326	793	1	garrido	garrido	PROPN
fnp-3326	793	2	-	-	PUNCT
fnp-3326	793	3	gil	gil	PROPN
fnp-3326	793	4	p	p	PROPN
fnp-3326	793	5	,	,	PUNCT
fnp-3326	793	6	rodriguez	rodriguez	NOUN
fnp-3326	793	7	-	-	PUNCT
fnp-3326	793	8	perez	perez	PROPN
fnp-3326	793	9	ai	ai	NOUN
fnp-3326	793	10	,	,	PUNCT
fnp-3326	793	11	dominguez	dominguez	PROPN
fnp-3326	793	12	-	-	PUNCT
fnp-3326	793	13	meijide	meijide	PROPN
fnp-3326	793	14	a	a	PRON
fnp-3326	793	15	,	,	PUNCT
fnp-3326	793	16	guerra	guerra	PROPN
fnp-3326	793	17	mj	mj	PROPN
fnp-3326	793	18	,	,	PUNCT
fnp-3326	793	19	labandeira	labandeira	PROPN
fnp-3326	793	20	-	-	PUNCT
fnp-3326	793	21	garcia	garcia	PROPN
fnp-3326	793	22	jl	jl	PROPN
fnp-3326	793	23	.	.	PUNCT
fnp-3326	794	1	bidirectional	bidirectional	ADJ
fnp-3326	794	2	neural	neural	ADJ
fnp-3326	794	3	interaction	interaction	NOUN
fnp-3326	794	4	between	between	ADP
fnp-3326	794	5	central	central	ADJ
fnp-3326	794	6	dopaminergic	dopaminergic	ADJ
fnp-3326	794	7	and	and	CCONJ
fnp-3326	794	8	gut	gut	NOUN
fnp-3326	794	9	lesions	lesion	NOUN
fnp-3326	794	10	in	in	ADP
fnp-3326	794	11	parkinson	parkinson	NOUN
fnp-3326	794	12	’s	’s	PART
fnp-3326	794	13	disease	disease	NOUN
fnp-3326	794	14	models	model	NOUN
fnp-3326	794	15	.	.	PUNCT
fnp-3326	795	1	mol	mol	ADP
fnp-3326	795	2	neurobiol	neurobiol	PROPN
fnp-3326	795	3	.	.	PUNCT
fnp-3326	796	1	2018;55:7297	2018;55:7297	NUM
fnp-3326	796	2	-	-	SYM
fnp-3326	796	3	7316	7316	NUM
fnp-3326	796	4	81	81	NUM
fnp-3326	796	5	.	.	PUNCT
fnp-3326	797	1	labrie	labrie	PROPN
fnp-3326	797	2	v	v	PROPN
fnp-3326	797	3	,	,	PUNCT
fnp-3326	797	4	brundin	brundin	ADJ
fnp-3326	797	5	p.	p.	NOUN
fnp-3326	797	6	alpha	alpha	PROPN
fnp-3326	797	7	-	-	PUNCT
fnp-3326	797	8	synuclein	synuclein	NOUN
fnp-3326	797	9	to	to	ADP
fnp-3326	797	10	the	the	DET
fnp-3326	797	11	rescue	rescue	NOUN
fnp-3326	797	12	:	:	PUNCT
fnp-3326	797	13	immune	immune	ADJ
fnp-3326	797	14	cell	cell	NOUN
fnp-3326	797	15	recruitment	recruitment	NOUN
fnp-3326	797	16	by	by	ADP
fnp-3326	797	17	alpha	alpha	NOUN
fnp-3326	797	18	-	-	PUNCT
fnp-3326	797	19	synuclein	synuclein	NOUN
fnp-3326	797	20	during	during	ADP
fnp-3326	797	21	gastrointestinal	gastrointestinal	ADJ
fnp-3326	797	22	infection	infection	NOUN
fnp-3326	797	23	.	.	PUNCT
fnp-3326	798	1	jin	jin	NOUN
fnp-3326	798	2	.	.	PUNCT
fnp-3326	799	1	2017;9:437–40	2017;9:437–40	X
fnp-3326	799	2	.	.	PROPN
fnp-3326	800	1	82	82	NUM
fnp-3326	800	2	.	.	PUNCT
fnp-3326	801	1	prigent	prigent	PROPN
fnp-3326	801	2	a	a	PROPN
fnp-3326	801	3	,	,	PUNCT
fnp-3326	801	4	gonzales	gonzales	PROPN
fnp-3326	801	5	j	j	PROPN
fnp-3326	801	6	,	,	PUNCT
fnp-3326	801	7	durand	durand	PROPN
fnp-3326	801	8	t	t	PROPN
fnp-3326	801	9	,	,	PUNCT
fnp-3326	801	10	le	le	PROPN
fnp-3326	801	11	berre	berre	PROPN
fnp-3326	801	12	-	-	PUNCT
fnp-3326	801	13	scoul	scoul	PROPN
fnp-3326	801	14	c	c	NOUN
fnp-3326	801	15	,	,	PUNCT
fnp-3326	801	16	rolli	rolli	NOUN
fnp-3326	801	17	-	-	PUNCT
fnp-3326	801	18	derkinderen	derkinderen	NOUN
fnp-3326	801	19	m	m	PROPN
fnp-3326	801	20	,	,	PUNCT
fnp-3326	801	21	neunlist	neunlist	PROPN
fnp-3326	801	22	m	m	PROPN
fnp-3326	801	23	,	,	PUNCT
fnp-3326	801	24	et	et	PROPN
fnp-3326	801	25	al	al	PROPN
fnp-3326	801	26	.	.	PROPN
fnp-3326	801	27	acute	acute	PROPN
fnp-3326	801	28	inflammation	inflammation	NOUN
fnp-3326	801	29	down	down	ADJ
fnp-3326	801	30	-	-	PUNCT
fnp-3326	801	31	regulates	regulate	VERB
fnp-3326	801	32	alpha	alpha	NOUN
fnp-3326	801	33	-	-	PUNCT
fnp-3326	801	34	synuclein	synuclein	NOUN
fnp-3326	801	35	expression	expression	NOUN
fnp-3326	801	36	in	in	ADP
fnp-3326	801	37	enteric	enteric	ADJ
fnp-3326	801	38	neurons	neuron	NOUN
fnp-3326	801	39	.	.	PUNCT
fnp-3326	802	1	j	j	PROPN
fnp-3326	802	2	neurochem	neurochem	PROPN
fnp-3326	802	3	.	.	PUNCT
fnp-3326	803	1	2019;148:746–60	2019;148:746–60	NUM
fnp-3326	803	2	.	.	PROPN
fnp-3326	803	3	83	83	NUM
fnp-3326	803	4	.	.	PUNCT
fnp-3326	804	1	resnikoff	resnikoff	NOUN
fnp-3326	804	2	h	h	NOUN
fnp-3326	804	3	,	,	PUNCT
fnp-3326	804	4	metzger	metzger	PROPN
fnp-3326	804	5	jm	jm	PROPN
fnp-3326	804	6	,	,	PUNCT
fnp-3326	804	7	lopez	lopez	PROPN
fnp-3326	804	8	m	m	PROPN
fnp-3326	804	9	,	,	PUNCT
fnp-3326	804	10	bondarenko	bondarenko	PROPN
fnp-3326	804	11	v	v	NOUN
fnp-3326	804	12	,	,	PUNCT
fnp-3326	804	13	mejia	mejia	PROPN
fnp-3326	804	14	a	a	PROPN
fnp-3326	804	15	,	,	PUNCT
fnp-3326	804	16	simmons	simmons	PROPN
fnp-3326	804	17	ha	ha	INTJ
fnp-3326	804	18	,	,	PUNCT
fnp-3326	804	19	et	et	PROPN
fnp-3326	804	20	al	al	PROPN
fnp-3326	804	21	.	.	PUNCT
fnp-3326	805	1	colonic	colonic	ADJ
fnp-3326	805	2	inflammation	inflammation	NOUN
fnp-3326	805	3	affects	affect	VERB
fnp-3326	805	4	myenteric	myenteric	ADV
fnp-3326	805	5	alpha	alpha	NOUN
fnp-3326	805	6	-	-	PUNCT
fnp-3326	805	7	synuclein	synuclein	NOUN
fnp-3326	805	8	in	in	ADP
fnp-3326	805	9	nonhuman	nonhuman	ADJ
fnp-3326	805	10	primates	primate	NOUN
fnp-3326	805	11	.	.	PUNCT
fnp-3326	806	1	j	j	PROPN
fnp-3326	806	2	inflamm	inflamm	PROPN
fnp-3326	806	3	res	re	NOUN
fnp-3326	806	4	.	.	PUNCT
fnp-3326	807	1	2019;12:113–26	2019;12:113–26	NUM
fnp-3326	807	2	.	.	NOUN
fnp-3326	807	3	84	84	NUM
fnp-3326	807	4	.	.	PUNCT
fnp-3326	808	1	whittem	whittem	PROPN
fnp-3326	808	2	cg	cg	PROPN
fnp-3326	808	3	,	,	PUNCT
fnp-3326	808	4	williams	williams	PROPN
fnp-3326	808	5	ad	ad	PROPN
fnp-3326	808	6	,	,	PUNCT
fnp-3326	808	7	williams	williams	PROPN
fnp-3326	808	8	cs	cs	PROPN
fnp-3326	808	9	.	.	PROPN
fnp-3326	808	10	murine	murine	ADJ
fnp-3326	808	11	colitis	colitis	NOUN
fnp-3326	808	12	modeling	modeling	NOUN
fnp-3326	808	13	using	use	VERB
fnp-3326	808	14	dextran	dextran	VERB
fnp-3326	808	15	sulfate	sulfate	NOUN
fnp-3326	808	16	sodium	sodium	NOUN
fnp-3326	808	17	(	(	PUNCT
fnp-3326	808	18	dss	dss	NOUN
fnp-3326	808	19	)	)	PUNCT
fnp-3326	808	20	.	.	PUNCT
fnp-3326	809	1	j	j	PROPN
fnp-3326	809	2	vis	vis	X
fnp-3326	809	3	exp	exp	NOUN
fnp-3326	809	4	[	[	X
fnp-3326	809	5	internet	internet	NOUN
fnp-3326	809	6	]	]	PUNCT
fnp-3326	809	7	.	.	PUNCT
fnp-3326	810	1	2010	2010	NUM
fnp-3326	811	1	[	[	X
fnp-3326	811	2	cited	cite	VERB
fnp-3326	811	3	2019	2019	NUM
fnp-3326	811	4	apr	apr	NOUN
fnp-3326	811	5	27	27	NUM
fnp-3326	811	6	]	]	PUNCT
fnp-3326	811	7	;	;	PUNCT
fnp-3326	811	8	available	available	ADJ
fnp-3326	811	9	from	from	ADP
fnp-3326	811	10	:	:	PUNCT
fnp-3326	811	11	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc2841571/	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc2841571/	NOUN
fnp-3326	811	12	85	85	NUM
fnp-3326	811	13	.	.	PUNCT
fnp-3326	812	1	erny	erny	NOUN
fnp-3326	812	2	d	d	PROPN
fnp-3326	812	3	,	,	PUNCT
fnp-3326	812	4	hrabě	hrabě	PROPN
fnp-3326	812	5	de	de	PROPN
fnp-3326	812	6	angelis	angelis	PROPN
fnp-3326	812	7	al	al	PROPN
fnp-3326	812	8	,	,	PUNCT
fnp-3326	812	9	jaitin	jaitin	PROPN
fnp-3326	812	10	d	d	PROPN
fnp-3326	812	11	,	,	PUNCT
fnp-3326	812	12	wieghofer	wieghofer	VERB
fnp-3326	812	13	p	p	PRON
fnp-3326	812	14	,	,	PUNCT
fnp-3326	812	15	staszewski	staszewski	NOUN
fnp-3326	812	16	o	o	PROPN
fnp-3326	812	17	,	,	PUNCT
fnp-3326	812	18	david	david	PROPN
fnp-3326	812	19	e	e	PROPN
fnp-3326	812	20	,	,	PUNCT
fnp-3326	812	21	et	et	PROPN
fnp-3326	812	22	al	al	PROPN
fnp-3326	812	23	.	.	PROPN
fnp-3326	812	24	host	host	NOUN
fnp-3326	812	25	microbiota	microbiota	NOUN
fnp-3326	812	26	constantly	constantly	ADV
fnp-3326	812	27	control	control	VERB
fnp-3326	812	28	maturation	maturation	NOUN
fnp-3326	812	29	and	and	CCONJ
fnp-3326	812	30	function	function	NOUN
fnp-3326	812	31	of	of	ADP
fnp-3326	812	32	microglia	microglia	NOUN
fnp-3326	812	33	in	in	ADP
fnp-3326	812	34	the	the	DET
fnp-3326	812	35	cns	cns	NOUN
fnp-3326	812	36	.	.	PUNCT
fnp-3326	813	1	nat	nat	PROPN
fnp-3326	813	2	neurosci	neurosci	PROPN
fnp-3326	813	3	.	.	PUNCT
fnp-3326	814	1	2015;18:965–77	2015;18:965–77	X
fnp-3326	814	2	.	.	PROPN
fnp-3326	815	1	86	86	NUM
fnp-3326	815	2	.	.	X
fnp-3326	816	1	sampson	sampson	NOUN
fnp-3326	816	2	tr	tr	VERB
fnp-3326	816	3	,	,	PUNCT
fnp-3326	816	4	debelius	debelius	ADJ
fnp-3326	816	5	jw	jw	PROPN
fnp-3326	816	6	,	,	PUNCT
fnp-3326	816	7	thron	thron	PROPN
fnp-3326	816	8	t	t	PROPN
fnp-3326	816	9	,	,	PUNCT
fnp-3326	816	10	janssen	janssen	PROPN
fnp-3326	816	11	s	s	PROPN
fnp-3326	816	12	,	,	PUNCT
fnp-3326	816	13	shastri	shastri	PROPN
fnp-3326	816	14	gg	gg	PROPN
fnp-3326	816	15	,	,	PUNCT
fnp-3326	816	16	ilhan	ilhan	PROPN
fnp-3326	816	17	ze	ze	PROPN
fnp-3326	816	18	,	,	PUNCT
fnp-3326	816	19	et	et	PROPN
fnp-3326	816	20	al	al	PROPN
fnp-3326	816	21	.	.	PUNCT
fnp-3326	817	1	gut	gut	NOUN
fnp-3326	817	2	microbiota	microbiota	NOUN
fnp-3326	817	3	regulate	regulate	NOUN
fnp-3326	817	4	motor	motor	NOUN
fnp-3326	817	5	deficits	deficit	NOUN
fnp-3326	817	6	and	and	CCONJ
fnp-3326	817	7	neuroinflammation	neuroinflammation	NOUN
fnp-3326	817	8	in	in	ADP
fnp-3326	817	9	a	a	DET
fnp-3326	817	10	model	model	NOUN
fnp-3326	817	11	of	of	ADP
fnp-3326	817	12	parkinson	parkinson	NOUN
fnp-3326	817	13	’s	’s	PART
fnp-3326	817	14	disease	disease	NOUN
fnp-3326	817	15	.	.	PUNCT
fnp-3326	818	1	cell	cell	NOUN
fnp-3326	818	2	.	.	PUNCT
fnp-3326	819	1	2016;167:1469	2016;167:1469	NUM
fnp-3326	819	2	-	-	SYM
fnp-3326	819	3	1480.e12	1480.e12	NUM
fnp-3326	819	4	.	.	PUNCT
fnp-3326	820	1	87	87	NUM
fnp-3326	820	2	.	.	PUNCT
fnp-3326	821	1	chen	chen	PROPN
fnp-3326	821	2	sg	sg	PROPN
fnp-3326	821	3	,	,	PUNCT
fnp-3326	821	4	stribinskis	stribinskis	PROPN
fnp-3326	821	5	v	v	PROPN
fnp-3326	821	6	,	,	PUNCT
fnp-3326	821	7	rane	rane	PROPN
fnp-3326	821	8	mj	mj	PROPN
fnp-3326	821	9	,	,	PUNCT
fnp-3326	821	10	demuth	demuth	PROPN
fnp-3326	821	11	dr	dr	PROPN
fnp-3326	821	12	,	,	PUNCT
fnp-3326	821	13	gozal	gozal	NOUN
fnp-3326	821	14	e	e	PROPN
fnp-3326	821	15	,	,	PUNCT
fnp-3326	821	16	roberts	roberts	PROPN
fnp-3326	821	17	am	am	PROPN
fnp-3326	821	18	,	,	PUNCT
fnp-3326	821	19	et	et	PROPN
fnp-3326	821	20	al	al	PROPN
fnp-3326	821	21	.	.	PROPN
fnp-3326	821	22	exposure	exposure	NOUN
fnp-3326	821	23	to	to	ADP
fnp-3326	821	24	the	the	DET
fnp-3326	821	25	functional	functional	ADJ
fnp-3326	821	26	bacterial	bacterial	ADJ
fnp-3326	821	27	amyloid	amyloid	NOUN
fnp-3326	821	28	protein	protein	NOUN
fnp-3326	821	29	curli	curli	NOUN
fnp-3326	821	30	enhances	enhance	VERB
fnp-3326	821	31	alpha	alpha	NOUN
fnp-3326	821	32	-	-	PUNCT
fnp-3326	821	33	synuclein	synuclein	NOUN
fnp-3326	821	34	aggregation	aggregation	NOUN
fnp-3326	821	35	in	in	ADP
fnp-3326	821	36	aged	aged	ADJ
fnp-3326	821	37	fischer	fischer	NOUN
fnp-3326	821	38	344	344	NUM
fnp-3326	821	39	rats	rat	NOUN
fnp-3326	821	40	and	and	CCONJ
fnp-3326	821	41	caenorhabditis	caenorhabditis	PROPN
fnp-3326	821	42	elegans	elegan	NOUN
fnp-3326	821	43	.	.	PUNCT
fnp-3326	822	1	scientific	scientific	ADJ
fnp-3326	822	2	reports	report	NOUN
fnp-3326	822	3	.	.	PUNCT
fnp-3326	823	1	2016;6:34477	2016;6:34477	NOUN
fnp-3326	823	2	.	.	PUNCT
fnp-3326	824	1	88	88	NUM
fnp-3326	824	2	.	.	PUNCT
fnp-3326	825	1	wendeln	wendeln	PROPN
fnp-3326	825	2	a	a	X
fnp-3326	825	3	-	-	PUNCT
fnp-3326	825	4	c	c	NOUN
fnp-3326	825	5	,	,	PUNCT
fnp-3326	825	6	degenhardt	degenhardt	ADJ
fnp-3326	825	7	k	k	PROPN
fnp-3326	825	8	,	,	PUNCT
fnp-3326	825	9	kaurani	kaurani	PROPN
fnp-3326	825	10	l	l	PROPN
fnp-3326	825	11	,	,	PUNCT
fnp-3326	825	12	gertig	gertig	PROPN
fnp-3326	825	13	m	m	PROPN
fnp-3326	825	14	,	,	PUNCT
fnp-3326	825	15	ulas	ulas	PROPN
fnp-3326	825	16	t	t	PROPN
fnp-3326	825	17	,	,	PUNCT
fnp-3326	825	18	jain	jain	PROPN
fnp-3326	825	19	g	g	PROPN
fnp-3326	825	20	,	,	PUNCT
fnp-3326	825	21	et	et	PROPN
fnp-3326	825	22	al	al	PROPN
fnp-3326	825	23	.	.	PROPN
fnp-3326	825	24	innate	innate	ADJ
fnp-3326	825	25	immune	immune	ADJ
fnp-3326	825	26	memory	memory	NOUN
fnp-3326	825	27	in	in	ADP
fnp-3326	825	28	the	the	DET
fnp-3326	825	29	brain	brain	NOUN
fnp-3326	825	30	shapes	shape	NOUN
fnp-3326	825	31	neurological	neurological	ADJ
fnp-3326	825	32	disease	disease	NOUN
fnp-3326	825	33	hallmarks	hallmark	NOUN
fnp-3326	825	34	.	.	PUNCT
fnp-3326	826	1	nature	nature	NOUN
fnp-3326	826	2	.	.	PUNCT
fnp-3326	827	1	2018;556:332–8	2018;556:332–8	NUM
fnp-3326	827	2	.	.	PUNCT
fnp-3326	828	1	89	89	NUM
fnp-3326	828	2	.	.	PUNCT
fnp-3326	829	1	sacino	sacino	PROPN
fnp-3326	829	2	an	an	PROPN
fnp-3326	829	3	,	,	PUNCT
fnp-3326	829	4	brooks	brooks	PROPN
fnp-3326	829	5	m	m	PROPN
fnp-3326	829	6	,	,	PUNCT
fnp-3326	829	7	thomas	thomas	PROPN
fnp-3326	829	8	ma	ma	PROPN
fnp-3326	829	9	,	,	PUNCT
fnp-3326	829	10	mckinney	mckinney	PROPN
fnp-3326	829	11	ab	ab	PROPN
fnp-3326	829	12	,	,	PUNCT
fnp-3326	829	13	lee	lee	PROPN
fnp-3326	829	14	s	s	PROPN
fnp-3326	829	15	,	,	PUNCT
fnp-3326	829	16	regenhardt	regenhardt	ADJ
fnp-3326	829	17	rw	rw	NOUN
fnp-3326	829	18	,	,	PUNCT
fnp-3326	829	19	et	et	PROPN
fnp-3326	829	20	al	al	PROPN
fnp-3326	829	21	.	.	PROPN
fnp-3326	830	1	intramuscular	intramuscular	ADJ
fnp-3326	830	2	injection	injection	NOUN
fnp-3326	830	3	of	of	ADP
fnp-3326	830	4	α	α	NOUN
fnp-3326	830	5	-	-	PUNCT
fnp-3326	830	6	synuclein	synuclein	NOUN
fnp-3326	830	7	induces	induce	VERB
fnp-3326	830	8	cns	cns	PROPN
fnp-3326	830	9	α	α	PROPN
fnp-3326	830	10	-	-	PUNCT
fnp-3326	830	11	synuclein	synuclein	NOUN
fnp-3326	830	12	pathology	pathology	NOUN
fnp-3326	830	13	and	and	CCONJ
fnp-3326	830	14	a	a	DET
fnp-3326	830	15	rapid	rapid	ADJ
fnp-3326	830	16	-	-	PUNCT
fnp-3326	830	17	onset	onset	NOUN
fnp-3326	830	18	motor	motor	NOUN
fnp-3326	830	19	phenotype	phenotype	NOUN
fnp-3326	830	20	in	in	ADP
fnp-3326	830	21	transgenic	transgenic	NOUN
fnp-3326	830	22	mice	mouse	NOUN
fnp-3326	830	23	.	.	PUNCT
fnp-3326	831	1	proc	proc	PROPN
fnp-3326	831	2	natl	natl	PROPN
fnp-3326	831	3	acad	acad	PROPN
fnp-3326	831	4	sci	sci	PROPN
fnp-3326	831	5	u	u	PROPN
fnp-3326	831	6	s	s	NOUN
fnp-3326	831	7	a.	a.	NOUN
fnp-3326	831	8	2014;111:10732–7	2014;111:10732–7	NOUN
fnp-3326	831	9	.	.	PUNCT
fnp-3326	832	1	90	90	NUM
fnp-3326	832	2	.	.	PUNCT
fnp-3326	833	1	kim	kim	PROPN
fnp-3326	833	2	s	s	PROPN
fnp-3326	833	3	,	,	PUNCT
fnp-3326	833	4	kwon	kwon	VERB
fnp-3326	833	5	s	s	NOUN
fnp-3326	833	6	-	-	PUNCT
fnp-3326	833	7	h	h	NOUN
fnp-3326	833	8	,	,	PUNCT
fnp-3326	833	9	kam	kam	PROPN
fnp-3326	833	10	t	t	PROPN
fnp-3326	833	11	-	-	PUNCT
fnp-3326	833	12	i	i	PROPN
fnp-3326	833	13	,	,	PUNCT
fnp-3326	833	14	panicker	panicker	PROPN
fnp-3326	833	15	n	n	CCONJ
fnp-3326	833	16	,	,	PUNCT
fnp-3326	833	17	karuppagounder	karuppagounder	PROPN
fnp-3326	833	18	ss	ss	PROPN
fnp-3326	833	19	,	,	PUNCT
fnp-3326	833	20	lee	lee	PROPN
fnp-3326	833	21	s	s	PROPN
fnp-3326	833	22	,	,	PUNCT
fnp-3326	833	23	et	et	PROPN
fnp-3326	833	24	al	al	PROPN
fnp-3326	833	25	.	.	PUNCT
fnp-3326	834	1	transneuronal	transneuronal	ADJ
fnp-3326	834	2	propagation	propagation	NOUN
fnp-3326	834	3	of	of	ADP
fnp-3326	834	4	pathologic	pathologic	ADJ
fnp-3326	834	5	α	α	NOUN
fnp-3326	834	6	-	-	NOUN
fnp-3326	834	7	synuclein	synuclein	NOUN
fnp-3326	834	8	from	from	ADP
fnp-3326	834	9	the	the	DET
fnp-3326	834	10	gut	gut	NOUN
fnp-3326	834	11	to	to	ADP
fnp-3326	834	12	the	the	DET
fnp-3326	834	13	brain	brain	NOUN
fnp-3326	834	14	models	model	NOUN
fnp-3326	834	15	parkinson	parkinson	NOUN
fnp-3326	834	16	’s	’s	PART
fnp-3326	834	17	disease	disease	NOUN
fnp-3326	834	18	.	.	PUNCT
fnp-3326	835	1	neuron	neuron	PROPN
fnp-3326	836	1	[	[	X
fnp-3326	836	2	internet	internet	NOUN
fnp-3326	836	3	]	]	PUNCT
fnp-3326	836	4	.	.	PUNCT
fnp-3326	837	1	2019	2019	NUM
fnp-3326	838	1	[	[	X
fnp-3326	838	2	cited	cite	VERB
fnp-3326	838	3	2019	2019	NUM
fnp-3326	838	4	jul	jul	NOUN
fnp-3326	838	5	25];0	25];0	NUM
fnp-3326	838	6	.	.	PUNCT
fnp-3326	839	1	available	available	ADJ
fnp-3326	839	2	from	from	ADP
fnp-3326	839	3	:	:	PUNCT
fnp-3326	839	4	https://www.cell.com/neuron/abstract/s0896-6273(19)30488-x	https://www.cell.com/neuron/abstract/s0896-6273(19)30488-x	PROPN
fnp-3326	839	5	91	91	NUM
fnp-3326	839	6	.	.	PUNCT
fnp-3326	840	1	lohmann	lohmann	PROPN
fnp-3326	840	2	s	s	PROPN
fnp-3326	840	3	,	,	PUNCT
fnp-3326	840	4	bernis	bernis	VERB
fnp-3326	840	5	me	i	PRON
fnp-3326	840	6	,	,	PUNCT
fnp-3326	840	7	tachu	tachu	PROPN
fnp-3326	840	8	bj	bj	NOUN
fnp-3326	840	9	,	,	PUNCT
fnp-3326	840	10	ziemski	ziemski	PROPN
fnp-3326	840	11	a	a	PRON
fnp-3326	840	12	,	,	PUNCT
fnp-3326	840	13	grigoletto	grigoletto	PROPN
fnp-3326	840	14	j	j	PROPN
fnp-3326	840	15	,	,	PUNCT
fnp-3326	840	16	tamgüney	tamgüney	NOUN
fnp-3326	840	17	g.	g.	PROPN
fnp-3326	840	18	oral	oral	ADJ
fnp-3326	840	19	and	and	CCONJ
fnp-3326	840	20	intravenous	intravenous	ADJ
fnp-3326	840	21	transmission	transmission	NOUN
fnp-3326	840	22	of	of	ADP
fnp-3326	840	23	α	α	NOUN
fnp-3326	840	24	-	-	PUNCT
fnp-3326	840	25	synuclein	synuclein	NOUN
fnp-3326	840	26	fibrils	fibril	NOUN
fnp-3326	840	27	to	to	ADP
fnp-3326	840	28	mice	mouse	NOUN
fnp-3326	840	29	.	.	PUNCT
fnp-3326	841	1	acta	acta	PROPN
fnp-3326	841	2	neuropathol	neuropathol	PROPN
fnp-3326	841	3	.	.	PUNCT
fnp-3326	842	1	2019;138(4):515	2019;138(4):515	X
fnp-3326	842	2	-	-	SYM
fnp-3326	842	3	533	533	NUM
fnp-3326	842	4	.	.	NOUN
fnp-3326	842	5	92	92	NUM
fnp-3326	842	6	.	.	PUNCT
fnp-3326	843	1	uemura	uemura	PROPN
fnp-3326	843	2	n	n	CCONJ
fnp-3326	843	3	,	,	PUNCT
fnp-3326	843	4	yagi	yagi	ADJ
fnp-3326	843	5	h	h	NOUN
fnp-3326	843	6	,	,	PUNCT
fnp-3326	843	7	uemura	uemura	PROPN
fnp-3326	843	8	mt	mt	PROPN
fnp-3326	843	9	,	,	PUNCT
fnp-3326	843	10	hatanaka	hatanaka	PROPN
fnp-3326	843	11	y	y	PROPN
fnp-3326	843	12	,	,	PUNCT
fnp-3326	843	13	yamakado	yamakado	PROPN
fnp-3326	843	14	h	h	PROPN
fnp-3326	843	15	,	,	PUNCT
fnp-3326	843	16	takahashi	takahashi	PROPN
fnp-3326	843	17	r.	r.	PROPN
fnp-3326	843	18	inoculation	inoculation	PROPN
fnp-3326	843	19	of	of	ADP
fnp-3326	843	20	α	α	PROPN
fnp-3326	843	21	-	-	PUNCT
fnp-3326	843	22	synuclein	synuclein	NOUN
fnp-3326	843	23	preformed	preformed	ADJ
fnp-3326	843	24	fibrils	fibril	NOUN
fnp-3326	843	25	into	into	ADP
fnp-3326	843	26	the	the	DET
fnp-3326	843	27	mouse	mouse	NOUN
fnp-3326	843	28	gastrointestinal	gastrointestinal	ADJ
fnp-3326	843	29	tract	tract	NOUN
fnp-3326	843	30	induces	induce	VERB
fnp-3326	843	31	lewy	lewy	ADJ
fnp-3326	843	32	body	body	NOUN
fnp-3326	843	33	-	-	PUNCT
fnp-3326	843	34	like	like	ADJ
fnp-3326	843	35	aggregates	aggregate	NOUN
fnp-3326	843	36	in	in	ADP
fnp-3326	843	37	the	the	DET
fnp-3326	843	38	brainstem	brainstem	NOUN
fnp-3326	843	39	via	via	ADP
fnp-3326	843	40	the	the	DET
fnp-3326	843	41	vagus	vagus	NOUN
fnp-3326	843	42	nerve	nerve	NOUN
fnp-3326	843	43	.	.	PUNCT
fnp-3326	844	1	molecular	molecular	ADJ
fnp-3326	844	2	neurodegeneration	neurodegeneration	NOUN
fnp-3326	844	3	.	.	PUNCT
fnp-3326	845	1	2018;13:21	2018;13:21	NUM
fnp-3326	845	2	.	.	PUNCT
fnp-3326	846	1	93	93	NUM
fnp-3326	846	2	.	.	PUNCT
fnp-3326	847	1	svensson	svensson	PROPN
fnp-3326	847	2	e	e	PROPN
fnp-3326	847	3	,	,	PUNCT
fnp-3326	847	4	horváth	horváth	PROPN
fnp-3326	847	5	-	-	PUNCT
fnp-3326	847	6	puhó	puhó	PROPN
fnp-3326	847	7	e	e	NOUN
fnp-3326	847	8	,	,	PUNCT
fnp-3326	847	9	thomsen	thomsen	PROPN
fnp-3326	847	10	rw	rw	PROPN
fnp-3326	847	11	,	,	PUNCT
fnp-3326	847	12	djurhuus	djurhuus	PROPN
fnp-3326	847	13	jc	jc	PROPN
fnp-3326	847	14	,	,	PUNCT
fnp-3326	847	15	pedersen	pedersen	PROPN
fnp-3326	847	16	l	l	PROPN
fnp-3326	847	17	,	,	PUNCT
fnp-3326	847	18	borghammer	borghammer	PROPN
fnp-3326	847	19	p	p	NOUN
fnp-3326	847	20	,	,	PUNCT
fnp-3326	847	21	et	et	PROPN
fnp-3326	847	22	al	al	PROPN
fnp-3326	847	23	.	.	PROPN
fnp-3326	847	24	vagotomy	vagotomy	PROPN
fnp-3326	847	25	and	and	CCONJ
fnp-3326	847	26	subsequent	subsequent	ADJ
fnp-3326	847	27	risk	risk	NOUN
fnp-3326	847	28	of	of	ADP
fnp-3326	847	29	parkinson	parkinson	NOUN
fnp-3326	847	30	’s	’s	PART
fnp-3326	847	31	disease	disease	NOUN
fnp-3326	847	32	.	.	PUNCT
fnp-3326	848	1	ann	ann	PROPN
fnp-3326	848	2	neurol	neurol	PROPN
fnp-3326	848	3	.	.	PUNCT
fnp-3326	849	1	2015;78:522–9	2015;78:522–9	NUM
fnp-3326	849	2	.	.	PROPN
fnp-3326	850	1	94	94	NUM
fnp-3326	850	2	.	.	PUNCT
fnp-3326	851	1	tysnes	tysne	NOUN
fnp-3326	852	1	o	o	PROPN
fnp-3326	852	2	-	-	SYM
fnp-3326	852	3	b	b	PROPN
fnp-3326	852	4	,	,	PUNCT
fnp-3326	852	5	kenborg	kenborg	PROPN
fnp-3326	852	6	l	l	PROPN
fnp-3326	852	7	,	,	PUNCT
fnp-3326	852	8	herlofson	herlofson	PROPN
fnp-3326	852	9	k	k	PROPN
fnp-3326	852	10	,	,	PUNCT
fnp-3326	852	11	steding	stede	VERB
fnp-3326	852	12	-	-	PUNCT
fnp-3326	852	13	jessen	jessen	PROPN
fnp-3326	852	14	m	m	PROPN
fnp-3326	852	15	,	,	PUNCT
fnp-3326	852	16	horn	horn	AUX
fnp-3326	852	17	a	a	DET
fnp-3326	852	18	,	,	PUNCT
fnp-3326	852	19	olsen	olsen	PROPN
fnp-3326	852	20	jh	jh	PROPN
fnp-3326	852	21	,	,	PUNCT
fnp-3326	852	22	et	et	PROPN
fnp-3326	852	23	al	al	PROPN
fnp-3326	852	24	.	.	PROPN
fnp-3326	852	25	does	do	AUX
fnp-3326	852	26	vagotomy	vagotomy	ADV
fnp-3326	852	27	reduce	reduce	VERB
fnp-3326	852	28	the	the	DET
fnp-3326	852	29	risk	risk	NOUN
fnp-3326	852	30	of	of	ADP
fnp-3326	852	31	parkinson	parkinson	NOUN
fnp-3326	852	32	’s	’s	PART
fnp-3326	852	33	disease	disease	NOUN
fnp-3326	852	34	?	?	PUNCT
fnp-3326	853	1	ann	ann	PROPN
fnp-3326	853	2	neurol	neurol	PROPN
fnp-3326	853	3	.	.	PUNCT
fnp-3326	854	1	2015;78:1011–2	2015;78:1011–2	X
fnp-3326	854	2	.	.	PUNCT
fnp-3326	855	1	95	95	NUM
fnp-3326	855	2	.	.	PUNCT
fnp-3326	856	1	braak	braak	PROPN
fnp-3326	856	2	h	h	PROPN
fnp-3326	856	3	,	,	PUNCT
fnp-3326	856	4	sastre	sastre	PROPN
fnp-3326	856	5	m	m	PROPN
fnp-3326	856	6	,	,	PUNCT
fnp-3326	856	7	bohl	bohl	PROPN
fnp-3326	856	8	jre	jre	PROPN
fnp-3326	856	9	,	,	PUNCT
fnp-3326	856	10	de	de	PROPN
fnp-3326	856	11	vos	vos	PROPN
fnp-3326	856	12	rai	rai	PROPN
fnp-3326	856	13	,	,	PUNCT
fnp-3326	856	14	del	del	PROPN
fnp-3326	856	15	tredici	tredici	PROPN
fnp-3326	856	16	k.	k.	PROPN
fnp-3326	856	17	parkinson	parkinson	PROPN
fnp-3326	856	18	’s	’s	PART
fnp-3326	856	19	disease	disease	NOUN
fnp-3326	856	20	:	:	PUNCT
fnp-3326	856	21	lesions	lesion	NOUN
fnp-3326	856	22	in	in	ADP
fnp-3326	856	23	dorsal	dorsal	NOUN
fnp-3326	856	24	horn	horn	NOUN
fnp-3326	856	25	layer	layer	NOUN
fnp-3326	856	26	i	i	PRON
fnp-3326	856	27	,	,	PUNCT
fnp-3326	856	28	involvement	involvement	NOUN
fnp-3326	856	29	of	of	ADP
fnp-3326	856	30	parasympathetic	parasympathetic	ADJ
fnp-3326	856	31	and	and	CCONJ
fnp-3326	856	32	sympathetic	sympathetic	ADJ
fnp-3326	856	33	preand	preand	NOUN
fnp-3326	856	34	postganglionic	postganglionic	ADJ
fnp-3326	856	35	neurons	neuron	NOUN
fnp-3326	856	36	.	.	PUNCT
fnp-3326	857	1	acta	acta	PROPN
fnp-3326	857	2	neuropathol	neuropathol	PROPN
fnp-3326	857	3	.	.	PUNCT
fnp-3326	858	1	2007;113:421–9	2007;113:421–9	NOUN
fnp-3326	858	2	.	.	PUNCT
fnp-3326	859	1	96	96	NUM
fnp-3326	859	2	.	.	PUNCT
fnp-3326	860	1	reeve	reeve	PROPN
fnp-3326	860	2	a	a	PRON
fnp-3326	860	3	,	,	PUNCT
fnp-3326	860	4	simcox	simcox	PROPN
fnp-3326	860	5	e	e	PROPN
fnp-3326	860	6	,	,	PUNCT
fnp-3326	860	7	turnbull	turnbull	PROPN
fnp-3326	860	8	d.	d.	PROPN
fnp-3326	860	9	ageing	ageing	NOUN
fnp-3326	860	10	and	and	CCONJ
fnp-3326	860	11	parkinson	parkinson	NOUN
fnp-3326	860	12	’s	’s	PART
fnp-3326	860	13	disease	disease	NOUN
fnp-3326	860	14	:	:	PUNCT
fnp-3326	860	15	why	why	SCONJ
fnp-3326	860	16	is	be	AUX
fnp-3326	860	17	advancing	advance	VERB
fnp-3326	860	18	age	age	NOUN
fnp-3326	860	19	the	the	DET
fnp-3326	860	20	biggest	big	ADJ
fnp-3326	860	21	risk	risk	NOUN
fnp-3326	860	22	factor	factor	NOUN
fnp-3326	860	23	?	?	PUNCT
fnp-3326	860	24	ageing	age	VERB
fnp-3326	860	25	research	research	NOUN
fnp-3326	860	26	reviews	review	NOUN
fnp-3326	860	27	.	.	PUNCT
fnp-3326	861	1	2014;14:19–30	2014;14:19–30	NUM
fnp-3326	861	2	.	.	PUNCT
fnp-3326	862	1	97	97	NUM
fnp-3326	862	2	.	.	PUNCT
fnp-3326	862	3	neumann	neumann	PROPN
fnp-3326	862	4	j	j	PROPN
fnp-3326	862	5	,	,	PUNCT
fnp-3326	862	6	bras	bras	PROPN
fnp-3326	862	7	j	j	PROPN
fnp-3326	862	8	,	,	PUNCT
fnp-3326	862	9	deas	deas	PROPN
fnp-3326	862	10	e	e	PROPN
fnp-3326	862	11	,	,	PUNCT
fnp-3326	862	12	o’sullivan	o’sullivan	NOUN
fnp-3326	862	13	ss	ss	NOUN
fnp-3326	862	14	,	,	PUNCT
fnp-3326	862	15	parkkinen	parkkinen	PROPN
fnp-3326	862	16	l	l	NOUN
fnp-3326	862	17	,	,	PUNCT
fnp-3326	862	18	lachmann	lachmann	PROPN
fnp-3326	862	19	rh	rh	PROPN
fnp-3326	862	20	,	,	PUNCT
fnp-3326	862	21	et	et	PROPN
fnp-3326	862	22	al	al	PROPN
fnp-3326	862	23	.	.	PUNCT
fnp-3326	863	1	glucocerebrosidase	glucocerebrosidase	PROPN
fnp-3326	863	2	mutations	mutation	NOUN
fnp-3326	863	3	in	in	ADP
fnp-3326	863	4	clinical	clinical	ADJ
fnp-3326	863	5	and	and	CCONJ
fnp-3326	863	6	pathologically	pathologically	ADV
fnp-3326	863	7	proven	prove	VERB
fnp-3326	863	8	parkinson	parkinson	NOUN
fnp-3326	863	9	’s	’s	PART
fnp-3326	863	10	disease	disease	NOUN
fnp-3326	863	11	.	.	PUNCT
fnp-3326	864	1	brain	brain	NOUN
fnp-3326	864	2	.	.	PUNCT
fnp-3326	865	1	2009;132:1783–94	2009;132:1783–94	X
fnp-3326	865	2	.	.	PUNCT
fnp-3326	866	1	98	98	NUM
fnp-3326	866	2	.	.	PUNCT
fnp-3326	867	1	nalls	nalls	PROPN
fnp-3326	867	2	ma	ma	PROPN
fnp-3326	867	3	,	,	PUNCT
fnp-3326	867	4	pankratz	pankratz	NOUN
fnp-3326	867	5	n	n	CCONJ
fnp-3326	867	6	,	,	PUNCT
fnp-3326	867	7	lill	lill	NOUN
fnp-3326	867	8	cm	cm	PROPN
fnp-3326	867	9	,	,	PUNCT
fnp-3326	867	10	do	do	AUX
fnp-3326	867	11	cb	cb	PROPN
fnp-3326	867	12	,	,	PUNCT
fnp-3326	867	13	hernandez	hernandez	PROPN
fnp-3326	867	14	dg	dg	PROPN
fnp-3326	867	15	,	,	PUNCT
fnp-3326	867	16	saad	saad	PROPN
fnp-3326	867	17	m	m	PROPN
fnp-3326	867	18	,	,	PUNCT
fnp-3326	867	19	et	et	PROPN
fnp-3326	867	20	al	al	PROPN
fnp-3326	867	21	.	.	PUNCT
fnp-3326	868	1	large	large	ADJ
fnp-3326	868	2	-	-	PUNCT
fnp-3326	868	3	scale	scale	NOUN
fnp-3326	868	4	meta	meta	ADJ
fnp-3326	868	5	-	-	PUNCT
fnp-3326	868	6	analysis	analysis	NOUN
fnp-3326	868	7	of	of	ADP
fnp-3326	868	8	genome	genome	NOUN
fnp-3326	868	9	-	-	PUNCT
fnp-3326	868	10	wide	wide	ADJ
fnp-3326	868	11	association	association	NOUN
fnp-3326	868	12	data	datum	NOUN
fnp-3326	868	13	identifies	identify	VERB
fnp-3326	868	14	six	six	NUM
fnp-3326	868	15	new	new	ADJ
fnp-3326	868	16	risk	risk	NOUN
fnp-3326	868	17	loci	loci	NOUN
fnp-3326	868	18	for	for	ADP
fnp-3326	868	19	parkinson	parkinson	NOUN
fnp-3326	868	20	’s	’s	PART
fnp-3326	868	21	disease	disease	NOUN
fnp-3326	868	22	.	.	PUNCT
fnp-3326	869	1	nat	nat	PROPN
fnp-3326	869	2	genet	genet	PROPN
fnp-3326	869	3	.	.	PUNCT
fnp-3326	870	1	2014;46:989–93	2014;46:989–93	NUM
fnp-3326	870	2	.	.	NOUN
fnp-3326	871	1	99	99	NUM
fnp-3326	871	2	.	.	PUNCT
fnp-3326	872	1	villumsen	villumsen	PROPN
fnp-3326	872	2	m	m	PROPN
fnp-3326	872	3	,	,	PUNCT
fnp-3326	872	4	aznar	aznar	PROPN
fnp-3326	872	5	s	s	PROPN
fnp-3326	872	6	,	,	PUNCT
fnp-3326	872	7	pakkenberg	pakkenberg	PROPN
fnp-3326	872	8	b	b	PROPN
fnp-3326	872	9	,	,	PUNCT
fnp-3326	872	10	jess	jess	PROPN
fnp-3326	872	11	t	t	PROPN
fnp-3326	872	12	,	,	PUNCT
fnp-3326	872	13	brudek	brudek	NOUN
fnp-3326	872	14	t.	t.	ADJ
fnp-3326	872	15	inflammatory	inflammatory	ADJ
fnp-3326	872	16	bowel	bowel	NOUN
fnp-3326	872	17	disease	disease	NOUN
fnp-3326	872	18	increases	increase	VERB
fnp-3326	872	19	the	the	DET
fnp-3326	872	20	risk	risk	NOUN
fnp-3326	872	21	of	of	ADP
fnp-3326	872	22	parkinson	parkinson	NOUN
fnp-3326	872	23	’s	’s	PART
fnp-3326	872	24	disease	disease	NOUN
fnp-3326	872	25	:	:	PUNCT
fnp-3326	872	26	a	a	DET
fnp-3326	872	27	danish	danish	ADJ
fnp-3326	872	28	nationwide	nationwide	ADJ
fnp-3326	872	29	cohort	cohort	NOUN
fnp-3326	872	30	study	study	NOUN
fnp-3326	872	31	1977	1977	NUM
fnp-3326	872	32	-	-	SYM
fnp-3326	872	33	2014	2014	NUM
fnp-3326	872	34	.	.	PUNCT
fnp-3326	873	1	gut	gut	INTJ
fnp-3326	873	2	.	.	PUNCT
fnp-3326	874	1	2018;68:18–24	2018;68:18–24	NUM
fnp-3326	874	2	.	.	PUNCT
fnp-3326	875	1	copyright	copyright	NOUN
fnp-3326	875	2	:	:	PUNCT
fnp-3326	875	3	©	©	PROPN
fnp-3326	875	4	2021	2021	NUM
fnp-3326	875	5	the	the	DET
fnp-3326	875	6	author(s	author(s	NOUN
fnp-3326	875	7	)	)	PUNCT
fnp-3326	875	8	.	.	PUNCT
fnp-3326	876	1	this	this	PRON
fnp-3326	876	2	is	be	AUX
fnp-3326	876	3	an	an	DET
fnp-3326	876	4	open	open	ADJ
fnp-3326	876	5	access	access	NOUN
fnp-3326	876	6	article	article	NOUN
fnp-3326	876	7	distributed	distribute	VERB
fnp-3326	876	8	under	under	ADP
fnp-3326	876	9	the	the	DET
fnp-3326	876	10	terms	term	NOUN
fnp-3326	876	11	of	of	ADP
fnp-3326	876	12	the	the	DET
fnp-3326	876	13	creative	creative	ADJ
fnp-3326	876	14	commons	common	NOUN
fnp-3326	876	15	attribution	attribution	NOUN
fnp-3326	876	16	4.0	4.0	NUM
fnp-3326	876	17	international	international	ADJ
fnp-3326	876	18	license	license	NOUN
fnp-3326	876	19	(	(	PUNCT
fnp-3326	876	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3326	876	21	)	)	PUNCT
fnp-3326	876	22	,	,	PUNCT
fnp-3326	876	23	which	which	PRON
fnp-3326	876	24	permits	permit	VERB
fnp-3326	876	25	unrestricted	unrestricted	ADJ
fnp-3326	876	26	use	use	NOUN
fnp-3326	876	27	,	,	PUNCT
fnp-3326	876	28	distribution	distribution	NOUN
fnp-3326	876	29	,	,	PUNCT
fnp-3326	876	30	and	and	CCONJ
fnp-3326	876	31	reproduction	reproduction	NOUN
fnp-3326	876	32	in	in	ADP
fnp-3326	876	33	any	any	DET
fnp-3326	876	34	medium	medium	NOUN
fnp-3326	876	35	,	,	PUNCT
fnp-3326	876	36	provided	provide	VERB
fnp-3326	876	37	the	the	DET
fnp-3326	876	38	original	original	ADJ
fnp-3326	876	39	author	author	NOUN
fnp-3326	876	40	and	and	CCONJ
fnp-3326	876	41	source	source	NOUN
fnp-3326	876	42	are	be	AUX
fnp-3326	876	43	credited	credit	VERB
fnp-3326	876	44	,	,	PUNCT
fnp-3326	876	45	a	a	DET
fnp-3326	876	46	link	link	NOUN
fnp-3326	876	47	to	to	ADP
fnp-3326	876	48	the	the	DET
fnp-3326	876	49	creative	creative	ADJ
fnp-3326	876	50	commons	common	NOUN
fnp-3326	876	51	license	license	NOUN
fnp-3326	876	52	is	be	AUX
fnp-3326	876	53	provided	provide	VERB
fnp-3326	876	54	,	,	PUNCT
fnp-3326	876	55	and	and	CCONJ
fnp-3326	876	56	any	any	DET
fnp-3326	876	57	changes	change	NOUN
fnp-3326	876	58	are	be	AUX
fnp-3326	876	59	indicated	indicate	VERB
fnp-3326	876	60	.	.	PUNCT
fnp-3326	877	1	the	the	DET
fnp-3326	877	2	creative	creative	ADJ
fnp-3326	877	3	commons	common	NOUN
fnp-3326	877	4	public	public	ADJ
fnp-3326	877	5	domain	domain	NOUN
fnp-3326	877	6	dedication	dedication	NOUN
fnp-3326	877	7	waiver	waiver	NOUN
fnp-3326	877	8	(	(	PUNCT
fnp-3326	877	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3326	877	10	)	)	PUNCT
fnp-3326	877	11	applies	apply	VERB
fnp-3326	877	12	to	to	ADP
fnp-3326	877	13	the	the	DET
fnp-3326	877	14	data	datum	NOUN
fnp-3326	877	15	made	make	VERB
fnp-3326	877	16	available	available	ADJ
fnp-3326	877	17	in	in	ADP
fnp-3326	877	18	this	this	DET
fnp-3326	877	19	article	article	NOUN
fnp-3326	877	20	,	,	PUNCT
fnp-3326	877	21	unless	unless	SCONJ
fnp-3326	877	22	otherwise	otherwise	ADV
fnp-3326	877	23	stated	state	VERB
fnp-3326	877	24	.	.	PUNCT