id	sid	tid	token	lemma	pos
fnp-3453	1	1	differential	differential	ADJ
fnp-3453	1	2	gene	gene	NOUN
fnp-3453	1	3	expression	expression	NOUN
fnp-3453	1	4	in	in	ADP
fnp-3453	1	5	the	the	DET
fnp-3453	1	6	cortical	cortical	ADJ
fnp-3453	1	7	sulcus	sulcus	NOUN
fnp-3453	1	8	compared	compare	VERB
fnp-3453	1	9	to	to	ADP
fnp-3453	1	10	the	the	DET
fnp-3453	1	11	gyral	gyral	ADJ
fnp-3453	1	12	crest	crest	NOUN
fnp-3453	1	13	within	within	ADP
fnp-3453	1	14	the	the	DET
fnp-3453	1	15	early	early	ADJ
fnp-3453	1	16	stages	stage	NOUN
fnp-3453	1	17	of	of	ADP
fnp-3453	1	18	chronic	chronic	ADJ
fnp-3453	1	19	traumatic	traumatic	ADJ
fnp-3453	1	20	encephalopathy	encephalopathy	NOUN
fnp-3453	1	21	feel	feel	VERB
fnp-3453	1	22	free	free	ADJ
fnp-3453	1	23	to	to	PART
fnp-3453	1	24	add	add	VERB
fnp-3453	1	25	comments	comment	NOUN
fnp-3453	1	26	by	by	ADP
fnp-3453	1	27	clicking	click	VERB
fnp-3453	1	28	these	these	DET
fnp-3453	1	29	icons	icon	NOUN
fnp-3453	1	30	on	on	ADP
fnp-3453	1	31	the	the	DET
fnp-3453	1	32	sidebar	sidebar	NOUN
fnp-3453	1	33	free	free	ADJ
fnp-3453	1	34	neuropathology	neuropathology	NOUN
fnp-3453	1	35	2:21	2:21	NUM
fnp-3453	1	36	(	(	PUNCT
fnp-3453	1	37	2021	2021	NUM
fnp-3453	1	38	)	)	PUNCT
fnp-3453	1	39	original	original	ADJ
fnp-3453	1	40	paper	paper	NOUN
fnp-3453	1	41	differential	differential	NOUN
fnp-3453	1	42	gene	gene	NOUN
fnp-3453	1	43	expression	expression	NOUN
fnp-3453	1	44	in	in	ADP
fnp-3453	1	45	the	the	DET
fnp-3453	1	46	cortical	cortical	ADJ
fnp-3453	1	47	sulcus	sulcus	NOUN
fnp-3453	1	48	compared	compare	VERB
fnp-3453	1	49	to	to	ADP
fnp-3453	1	50	the	the	DET
fnp-3453	1	51	gyral	gyral	ADJ
fnp-3453	1	52	crest	crest	NOUN
fnp-3453	1	53	within	within	ADP
fnp-3453	1	54	the	the	DET
fnp-3453	1	55	early	early	ADJ
fnp-3453	1	56	stages	stage	NOUN
fnp-3453	1	57	of	of	ADP
fnp-3453	1	58	chronic	chronic	ADJ
fnp-3453	1	59	traumatic	traumatic	ADJ
fnp-3453	1	60	encephalopathy	encephalopathy	NOUN
fnp-3453	1	61	jonathan	jonathan	PROPN
fnp-3453	1	62	d.	d.	PROPN
fnp-3453	1	63	cherry*1,2,3,4	cherry*1,2,3,4	PROPN
fnp-3453	1	64	,	,	PUNCT
fnp-3453	1	65	filisia	filisia	PROPN
fnp-3453	1	66	agus2,5	agus2,5	PROPN
fnp-3453	1	67	,	,	PUNCT
fnp-3453	1	68	erin	erin	PROPN
fnp-3453	1	69	dixon3,4	dixon3,4	PROPN
fnp-3453	1	70	,	,	PUNCT
fnp-3453	1	71	bertrand	bertrand	PROPN
fnp-3453	1	72	huber2,3,4,6	huber2,3,4,6	PROPN
fnp-3453	1	73	,	,	PUNCT
fnp-3453	1	74	victor	victor	PROPN
fnp-3453	1	75	e.	e.	PROPN
fnp-3453	1	76	alvarez2,3,4,7	alvarez2,3,4,7	PROPN
fnp-3453	1	77	,	,	PUNCT
fnp-3453	1	78	jesse	jesse	PROPN
fnp-3453	1	79	mez2,3	mez2,3	PROPN
fnp-3453	1	80	,	,	PUNCT
fnp-3453	1	81	ann	ann	PROPN
fnp-3453	1	82	c.	c.	PROPN
fnp-3453	1	83	mckee1,2,3,4,7	mckee1,2,3,4,7	PROPN
fnp-3453	1	84	,	,	PUNCT
fnp-3453	1	85	adam	adam	PROPN
fnp-3453	1	86	labadorf2,5,6	labadorf2,5,6	PROPN
fnp-3453	1	87	,	,	PUNCT
fnp-3453	1	88	thor	thor	PROPN
fnp-3453	1	89	d.	d.	PROPN
fnp-3453	1	90	stein1,3,4,7	stein1,3,4,7	PROPN
fnp-3453	2	1	1	1	NUM
fnp-3453	2	2	department	department	NOUN
fnp-3453	2	3	of	of	ADP
fnp-3453	2	4	pathology	pathology	NOUN
fnp-3453	2	5	and	and	CCONJ
fnp-3453	2	6	laboratory	laboratory	NOUN
fnp-3453	2	7	medicine	medicine	NOUN
fnp-3453	2	8	,	,	PUNCT
fnp-3453	2	9	boston	boston	PROPN
fnp-3453	2	10	university	university	PROPN
fnp-3453	2	11	school	school	NOUN
fnp-3453	2	12	of	of	ADP
fnp-3453	2	13	medicine	medicine	NOUN
fnp-3453	2	14	,	,	PUNCT
fnp-3453	2	15	boston	boston	PROPN
fnp-3453	2	16	ma	ma	PROPN
fnp-3453	2	17	,	,	PUNCT
fnp-3453	2	18	usa	usa	PROPN
fnp-3453	2	19	2	2	NUM
fnp-3453	2	20	department	department	NOUN
fnp-3453	2	21	of	of	ADP
fnp-3453	2	22	neurology	neurology	NOUN
fnp-3453	2	23	,	,	PUNCT
fnp-3453	2	24	boston	boston	PROPN
fnp-3453	2	25	university	university	PROPN
fnp-3453	2	26	school	school	NOUN
fnp-3453	2	27	of	of	ADP
fnp-3453	2	28	medicine	medicine	NOUN
fnp-3453	2	29	,	,	PUNCT
fnp-3453	2	30	boston	boston	PROPN
fnp-3453	2	31	ma	ma	PROPN
fnp-3453	2	32	,	,	PUNCT
fnp-3453	2	33	usa	usa	PROPN
fnp-3453	2	34	3	3	NUM
fnp-3453	2	35	boston	boston	PROPN
fnp-3453	2	36	university	university	PROPN
fnp-3453	2	37	alzheimer	alzheimer	PROPN
fnp-3453	2	38	’s	’s	PART
fnp-3453	2	39	disease	disease	NOUN
fnp-3453	2	40	and	and	CCONJ
fnp-3453	2	41	cte	cte	NOUN
fnp-3453	2	42	centers	center	NOUN
fnp-3453	2	43	,	,	PUNCT
fnp-3453	2	44	boston	boston	PROPN
fnp-3453	2	45	university	university	PROPN
fnp-3453	2	46	school	school	NOUN
fnp-3453	2	47	of	of	ADP
fnp-3453	2	48	medicine	medicine	NOUN
fnp-3453	2	49	,	,	PUNCT
fnp-3453	2	50	boston	boston	PROPN
fnp-3453	2	51	ma	ma	PROPN
fnp-3453	2	52	,	,	PUNCT
fnp-3453	2	53	usa	usa	PROPN
fnp-3453	2	54	4	4	NUM
fnp-3453	2	55	va	va	PROPN
fnp-3453	2	56	boston	boston	PROPN
fnp-3453	2	57	healthcare	healthcare	PROPN
fnp-3453	2	58	system	system	PROPN
fnp-3453	2	59	,	,	PUNCT
fnp-3453	2	60	jamaica	jamaica	PROPN
fnp-3453	2	61	plain	plain	PROPN
fnp-3453	2	62	ma	ma	PROPN
fnp-3453	2	63	,	,	PUNCT
fnp-3453	2	64	usa	usa	PROPN
fnp-3453	2	65	5	5	NUM
fnp-3453	2	66	bioinformatics	bioinformatics	NOUN
fnp-3453	2	67	program	program	NOUN
fnp-3453	2	68	,	,	PUNCT
fnp-3453	2	69	boston	boston	PROPN
fnp-3453	2	70	university	university	PROPN
fnp-3453	2	71	,	,	PUNCT
fnp-3453	2	72	boston	boston	PROPN
fnp-3453	2	73	ma	ma	PROPN
fnp-3453	2	74	,	,	PUNCT
fnp-3453	2	75	usa	usa	PROPN
fnp-3453	2	76	6	6	NUM
fnp-3453	2	77	national	national	ADJ
fnp-3453	2	78	center	center	NOUN
fnp-3453	2	79	for	for	ADP
fnp-3453	2	80	ptsd	ptsd	PROPN
fnp-3453	2	81	,	,	PUNCT
fnp-3453	2	82	va	va	PROPN
fnp-3453	2	83	boston	boston	PROPN
fnp-3453	2	84	healthcare	healthcare	PROPN
fnp-3453	2	85	system	system	PROPN
fnp-3453	2	86	,	,	PUNCT
fnp-3453	2	87	boston	boston	PROPN
fnp-3453	2	88	ma	ma	PROPN
fnp-3453	2	89	,	,	PUNCT
fnp-3453	2	90	usa	usa	PROPN
fnp-3453	2	91	7	7	NUM
fnp-3453	2	92	va	va	PROPN
fnp-3453	2	93	bedford	bedford	PROPN
fnp-3453	2	94	healthcare	healthcare	PROPN
fnp-3453	2	95	system	system	NOUN
fnp-3453	2	96	,	,	PUNCT
fnp-3453	2	97	bedford	bedford	PROPN
fnp-3453	2	98	ma	ma	PROPN
fnp-3453	2	99	,	,	PUNCT
fnp-3453	2	100	usa	usa	PROPN
fnp-3453	2	101	*	*	PUNCT
fnp-3453	2	102	corresponding	correspond	VERB
fnp-3453	2	103	authors	author	NOUN
fnp-3453	2	104	:	:	PUNCT
fnp-3453	2	105	jonathan	jonathan	PROPN
fnp-3453	2	106	d.	d.	PROPN
fnp-3453	2	107	cherry	cherry	PROPN
fnp-3453	2	108	,	,	PUNCT
fnp-3453	2	109	phd	phd	PROPN
fnp-3453	2	110	·	·	PUNCT
fnp-3453	2	111	va	va	PROPN
fnp-3453	2	112	boston	boston	PROPN
fnp-3453	2	113	healthcare	healthcare	PROPN
fnp-3453	2	114	system	system	PROPN
fnp-3453	2	115	·	·	PUNCT
fnp-3453	2	116	150	150	NUM
fnp-3453	2	117	s	s	NOUN
fnp-3453	2	118	huntington	huntington	PROPN
fnp-3453	2	119	ave	ave	PROPN
fnp-3453	2	120	·	·	PUNCT
fnp-3453	2	121	boston	boston	PROPN
fnp-3453	2	122	,	,	PUNCT
fnp-3453	2	123	ma	ma	PROPN
fnp-3453	2	124	02130	02130	NUM
fnp-3453	2	125	·	·	PUNCT
fnp-3453	2	126	usa	usa	PROPN
fnp-3453	2	127	jdcherry@bu.edu	jdcherry@bu.edu	PROPN
fnp-3453	2	128	thor	thor	PROPN
fnp-3453	2	129	d.	d.	PROPN
fnp-3453	2	130	stein	stein	PROPN
fnp-3453	2	131	,	,	PUNCT
fnp-3453	2	132	md	md	PROPN
fnp-3453	2	133	.	.	PROPN
fnp-3453	2	134	phd	phd	PROPN
fnp-3453	2	135	·	·	PUNCT
fnp-3453	2	136	va	va	PROPN
fnp-3453	2	137	boston	boston	PROPN
fnp-3453	2	138	healthcare	healthcare	PROPN
fnp-3453	2	139	system	system	PROPN
fnp-3453	2	140	·	·	PUNCT
fnp-3453	2	141	150	150	NUM
fnp-3453	2	142	s	s	NOUN
fnp-3453	2	143	huntington	huntington	PROPN
fnp-3453	2	144	ave	ave	PROPN
fnp-3453	2	145	·	·	PUNCT
fnp-3453	2	146	boston	boston	PROPN
fnp-3453	2	147	,	,	PUNCT
fnp-3453	2	148	ma	ma	PROPN
fnp-3453	2	149	02130	02130	NUM
fnp-3453	2	150	·	·	PUNCT
fnp-3453	2	151	usa	usa	PROPN
fnp-3453	2	152	tdstein@bu.edu	tdstein@bu.edu	PROPN
fnp-3453	2	153	submitted	submit	VERB
fnp-3453	2	154	:	:	PUNCT
fnp-3453	2	155	21	21	NUM
fnp-3453	2	156	july	july	PROPN
fnp-3453	2	157	2021	2021	NUM
fnp-3453	2	158	accepted	accept	VERB
fnp-3453	2	159	:	:	PUNCT
fnp-3453	2	160	12	12	NUM
fnp-3453	2	161	august	august	PROPN
fnp-3453	2	162	2021	2021	NUM
fnp-3453	2	163	copyedited	copyedit	VERB
fnp-3453	2	164	by	by	ADP
fnp-3453	2	165	:	:	PUNCT
fnp-3453	2	166	lauren	lauren	PROPN
fnp-3453	2	167	walker	walker	PROPN
fnp-3453	2	168	published	publish	VERB
fnp-3453	2	169	:	:	PUNCT
fnp-3453	3	1	17	17	NUM
fnp-3453	3	2	august	august	PROPN
fnp-3453	3	3	2021	2021	NUM
fnp-3453	3	4	https://doi.org/10.17879/freeneuropathology-2021-3453	https://doi.org/10.17879/freeneuropathology-2021-3453	ADP
fnp-3453	3	5	additional	additional	ADJ
fnp-3453	3	6	resources	resource	NOUN
fnp-3453	3	7	and	and	CCONJ
fnp-3453	3	8	electronic	electronic	ADJ
fnp-3453	3	9	supplementary	supplementary	ADJ
fnp-3453	3	10	material	material	NOUN
fnp-3453	3	11	:	:	PUNCT
fnp-3453	3	12	download	download	VERB
fnp-3453	3	13	supplementary	supplementary	ADJ
fnp-3453	3	14	material	material	NOUN
fnp-3453	3	15	keywords	keyword	NOUN
fnp-3453	3	16	:	:	PUNCT
fnp-3453	3	17	cte	cte	NOUN
fnp-3453	3	18	,	,	PUNCT
fnp-3453	3	19	rna	rna	PROPN
fnp-3453	3	20	-	-	PUNCT
fnp-3453	3	21	seq	seq	NOUN
fnp-3453	3	22	,	,	PUNCT
fnp-3453	3	23	repetitive	repetitive	ADJ
fnp-3453	3	24	head	head	NOUN
fnp-3453	3	25	trauma	trauma	NOUN
fnp-3453	3	26	,	,	PUNCT
fnp-3453	3	27	inflammation	inflammation	NOUN
fnp-3453	3	28	,	,	PUNCT
fnp-3453	3	29	tau	tau	PROPN
fnp-3453	3	30	,	,	PUNCT
fnp-3453	3	31	tbi	tbi	PROPN
fnp-3453	3	32	abstract	abstract	ADJ
fnp-3453	3	33	chronic	chronic	ADJ
fnp-3453	3	34	traumatic	traumatic	ADJ
fnp-3453	3	35	encephalopathy	encephalopathy	NOUN
fnp-3453	3	36	(	(	PUNCT
fnp-3453	3	37	cte	cte	NOUN
fnp-3453	3	38	)	)	PUNCT
fnp-3453	3	39	is	be	AUX
fnp-3453	3	40	a	a	DET
fnp-3453	3	41	progressive	progressive	ADJ
fnp-3453	3	42	neurodegenerative	neurodegenerative	ADJ
fnp-3453	3	43	tauopathy	tauopathy	NOUN
fnp-3453	3	44	found	find	VERB
fnp-3453	3	45	in	in	ADP
fnp-3453	3	46	individuals	individual	NOUN
fnp-3453	3	47	with	with	ADP
fnp-3453	3	48	a	a	DET
fnp-3453	3	49	history	history	NOUN
fnp-3453	3	50	of	of	ADP
fnp-3453	3	51	repetitive	repetitive	ADJ
fnp-3453	3	52	head	head	NOUN
fnp-3453	3	53	impacts	impact	NOUN
fnp-3453	3	54	(	(	PUNCT
fnp-3453	3	55	rhi	rhi	NOUN
fnp-3453	3	56	)	)	PUNCT
fnp-3453	3	57	.	.	PUNCT
fnp-3453	4	1	previous	previous	ADJ
fnp-3453	4	2	work	work	NOUN
fnp-3453	4	3	has	have	AUX
fnp-3453	4	4	demonstrated	demonstrate	VERB
fnp-3453	4	5	that	that	SCONJ
fnp-3453	4	6	neuroinflammation	neuroinflammation	NOUN
fnp-3453	4	7	is	be	AUX
fnp-3453	4	8	involved	involve	VERB
fnp-3453	4	9	in	in	ADP
fnp-3453	4	10	cte	cte	PROPN
fnp-3453	4	11	pathogenesis	pathogenesis	NOUN
fnp-3453	4	12	,	,	PUNCT
fnp-3453	4	13	however	however	ADV
fnp-3453	4	14	,	,	PUNCT
fnp-3453	4	15	the	the	DET
fnp-3453	4	16	specific	specific	ADJ
fnp-3453	4	17	inflammatory	inflammatory	ADJ
fnp-3453	4	18	mechanisms	mechanism	NOUN
fnp-3453	4	19	are	be	AUX
fnp-3453	4	20	still	still	ADV
fnp-3453	4	21	unclear	unclear	ADJ
fnp-3453	4	22	.	.	PUNCT
fnp-3453	5	1	here	here	ADV
fnp-3453	5	2	,	,	PUNCT
fnp-3453	5	3	using	use	VERB
fnp-3453	5	4	rna	rna	NOUN
fnp-3453	5	5	-	-	PUNCT
fnp-3453	5	6	sequencing	sequence	VERB
fnp-3453	5	7	and	and	CCONJ
fnp-3453	5	8	gene	gene	NOUN
fnp-3453	5	9	set	set	VERB
fnp-3453	5	10	enrichment	enrichment	NOUN
fnp-3453	5	11	analysis	analysis	NOUN
fnp-3453	5	12	(	(	PUNCT
fnp-3453	5	13	gsea	gsea	NOUN
fnp-3453	5	14	)	)	PUNCT
fnp-3453	5	15	,	,	PUNCT
fnp-3453	5	16	we	we	PRON
fnp-3453	5	17	investigated	investigate	VERB
fnp-3453	5	18	the	the	DET
fnp-3453	5	19	genetic	genetic	ADJ
fnp-3453	5	20	changes	change	NOUN
fnp-3453	5	21	found	find	VERB
fnp-3453	5	22	in	in	ADP
fnp-3453	5	23	tissue	tissue	NOUN
fnp-3453	5	24	taken	take	VERB
fnp-3453	5	25	from	from	ADP
fnp-3453	5	26	the	the	DET
fnp-3453	5	27	region	region	NOUN
fnp-3453	5	28	cte	cte	PROPN
fnp-3453	5	29	pathology	pathology	PROPN
fnp-3453	5	30	is	be	AUX
fnp-3453	5	31	first	first	ADV
fnp-3453	5	32	found	find	VERB
fnp-3453	5	33	,	,	PUNCT
fnp-3453	5	34	the	the	DET
fnp-3453	5	35	cortical	cortical	ADJ
fnp-3453	5	36	sulcus	sulcus	NOUN
fnp-3453	5	37	,	,	PUNCT
fnp-3453	5	38	and	and	CCONJ
fnp-3453	5	39	compared	compare	VERB
fnp-3453	5	40	it	it	PRON
fnp-3453	5	41	to	to	ADP
fnp-3453	5	42	neighboring	neighboring	NOUN
fnp-3453	5	43	gryal	gryal	ADJ
fnp-3453	5	44	crest	crest	NOUN
fnp-3453	5	45	tissue	tissue	NOUN
fnp-3453	5	46	to	to	PART
fnp-3453	5	47	identify	identify	VERB
fnp-3453	5	48	what	what	PRON
fnp-3453	5	49	pathways	pathway	NOUN
fnp-3453	5	50	were	be	AUX
fnp-3453	5	51	directly	directly	ADV
fnp-3453	5	52	related	relate	VERB
fnp-3453	5	53	to	to	ADP
fnp-3453	5	54	initial	initial	ADJ
fnp-3453	5	55	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-3453	5	56	tau	tau	PROPN
fnp-3453	5	57	(	(	PUNCT
fnp-3453	5	58	p	p	PROPN
fnp-3453	5	59	-	-	PUNCT
fnp-3453	5	60	tau	tau	NOUN
fnp-3453	5	61	)	)	PUNCT
fnp-3453	5	62	deposition	deposition	NOUN
fnp-3453	5	63	.	.	PUNCT
fnp-3453	6	1	21	21	NUM
fnp-3453	6	2	cases	case	NOUN
fnp-3453	6	3	were	be	AUX
fnp-3453	6	4	chosen	choose	VERB
fnp-3453	6	5	for	for	ADP
fnp-3453	6	6	analysis	analysis	NOUN
fnp-3453	6	7	:	:	PUNCT
fnp-3453	6	8	6	6	NUM
fnp-3453	6	9	cases	case	NOUN
fnp-3453	6	10	had	have	VERB
fnp-3453	6	11	no	no	DET
fnp-3453	6	12	exposure	exposure	NOUN
fnp-3453	6	13	to	to	ADP
fnp-3453	6	14	rhi	rhi	NOUN
fnp-3453	6	15	or	or	CCONJ
fnp-3453	6	16	presence	presence	NOUN
fnp-3453	6	17	of	of	ADP
fnp-3453	6	18	neurodegenerative	neurodegenerative	ADJ
fnp-3453	6	19	disease	disease	NOUN
fnp-3453	6	20	(	(	PUNCT
fnp-3453	6	21	control	control	NOUN
fnp-3453	6	22	)	)	PUNCT
fnp-3453	6	23	,	,	PUNCT
fnp-3453	6	24	5	5	NUM
fnp-3453	6	25	cases	case	NOUN
fnp-3453	6	26	had	have	VERB
fnp-3453	6	27	exposure	exposure	NOUN
fnp-3453	6	28	to	to	ADP
fnp-3453	6	29	rhi	rhi	PROPN
fnp-3453	6	30	but	but	CCONJ
fnp-3453	6	31	no	no	DET
fnp-3453	6	32	presence	presence	NOUN
fnp-3453	6	33	of	of	ADP
fnp-3453	6	34	neurodegenerative	neurodegenerative	ADJ
fnp-3453	6	35	disease	disease	NOUN
fnp-3453	6	36	(	(	PUNCT
fnp-3453	6	37	rhi	rhi	NOUN
fnp-3453	6	38	)	)	PUNCT
fnp-3453	6	39	,	,	PUNCT
fnp-3453	6	40	and	and	CCONJ
fnp-3453	6	41	10	10	NUM
fnp-3453	6	42	cases	case	NOUN
fnp-3453	6	43	had	have	VERB
fnp-3453	6	44	exposure	exposure	NOUN
fnp-3453	6	45	to	to	ADP
fnp-3453	6	46	rhi	rhi	PROPN
fnp-3453	6	47	and	and	CCONJ
fnp-3453	6	48	low	low	ADJ
fnp-3453	6	49	stage	stage	NOUN
fnp-3453	6	50	cte	cte	NOUN
fnp-3453	6	51	(	(	PUNCT
fnp-3453	6	52	cte	cte	PROPN
fnp-3453	6	53	)	)	PUNCT
fnp-3453	6	54	.	.	PUNCT
fnp-3453	7	1	two	two	NUM
fnp-3453	7	2	sets	set	NOUN
fnp-3453	7	3	of	of	ADP
fnp-3453	7	4	genes	gene	NOUN
fnp-3453	7	5	were	be	AUX
fnp-3453	7	6	identified	identify	VERB
fnp-3453	7	7	:	:	PUNCT
fnp-3453	7	8	genes	gene	NOUN
fnp-3453	7	9	that	that	PRON
fnp-3453	7	10	changed	change	VERB
fnp-3453	7	11	in	in	ADP
fnp-3453	7	12	both	both	CCONJ
fnp-3453	7	13	the	the	DET
fnp-3453	7	14	sulcus	sulcus	NOUN
fnp-3453	7	15	and	and	CCONJ
fnp-3453	7	16	crest	crest	NOUN
fnp-3453	7	17	and	and	CCONJ
fnp-3453	7	18	genes	gene	NOUN
fnp-3453	7	19	that	that	PRON
fnp-3453	7	20	changed	change	VERB
fnp-3453	7	21	specifically	specifically	ADV
fnp-3453	7	22	in	in	ADP
fnp-3453	7	23	the	the	DET
fnp-3453	7	24	sulcus	sulcus	NOUN
fnp-3453	7	25	relative	relative	ADV
fnp-3453	7	26	to	to	ADP
fnp-3453	7	27	the	the	DET
fnp-3453	7	28	crest	crest	NOUN
fnp-3453	7	29	.	.	PUNCT
fnp-3453	8	1	when	when	SCONJ
fnp-3453	8	2	examining	examine	VERB
fnp-3453	8	3	genes	gene	NOUN
fnp-3453	8	4	that	that	PRON
fnp-3453	8	5	changed	change	VERB
fnp-3453	8	6	in	in	ADP
fnp-3453	8	7	both	both	CCONJ
fnp-3453	8	8	the	the	DET
fnp-3453	8	9	sulcus	sulcus	NOUN
fnp-3453	8	10	and	and	CCONJ
fnp-3453	8	11	crest	crest	NOUN
fnp-3453	8	12	,	,	PUNCT
fnp-3453	8	13	gsea	gsea	PROPN
fnp-3453	8	14	demonstrated	demonstrate	VERB
fnp-3453	8	15	an	an	DET
fnp-3453	8	16	increase	increase	NOUN
fnp-3453	8	17	in	in	ADP
fnp-3453	8	18	immune	immune	ADJ
fnp-3453	8	19	related	relate	VERB
fnp-3453	8	20	processes	process	NOUN
fnp-3453	8	21	and	and	CCONJ
fnp-3453	8	22	a	a	DET
fnp-3453	8	23	decrease	decrease	NOUN
fnp-3453	8	24	in	in	ADP
fnp-3453	8	25	neuronal	neuronal	ADJ
fnp-3453	8	26	processes	process	NOUN
fnp-3453	8	27	in	in	ADP
fnp-3453	8	28	rhi	rhi	PROPN
fnp-3453	8	29	and	and	CCONJ
fnp-3453	8	30	cte	cte	PROPN
fnp-3453	8	31	groups	group	NOUN
fnp-3453	8	32	.	.	PUNCT
fnp-3453	9	1	sulcal	sulcal	ADJ
fnp-3453	9	2	specific	specific	ADJ
fnp-3453	9	3	alterations	alteration	NOUN
fnp-3453	9	4	were	be	AUX
fnp-3453	9	5	observed	observe	VERB
fnp-3453	9	6	to	to	PART
fnp-3453	9	7	be	be	AUX
fnp-3453	9	8	driven	drive	VERB
fnp-3453	9	9	by	by	ADP
fnp-3453	9	10	three	three	NUM
fnp-3453	9	11	mechanisms	mechanism	NOUN
fnp-3453	9	12	:	:	PUNCT
fnp-3453	9	13	anatomy	anatomy	NOUN
fnp-3453	9	14	,	,	PUNCT
fnp-3453	9	15	rhi	rhi	PROPN
fnp-3453	9	16	,	,	PUNCT
fnp-3453	9	17	or	or	CCONJ
fnp-3453	9	18	p	p	PROPN
fnp-3453	9	19	-	-	PUNCT
fnp-3453	9	20	tau	tau	NOUN
fnp-3453	9	21	.	.	PUNCT
fnp-3453	10	1	first	first	ADV
fnp-3453	10	2	,	,	PUNCT
fnp-3453	10	3	we	we	PRON
fnp-3453	10	4	observed	observe	VERB
fnp-3453	10	5	consistent	consistent	ADJ
fnp-3453	10	6	sulcal	sulcal	ADJ
fnp-3453	10	7	specific	specific	ADJ
fnp-3453	10	8	alterations	alteration	NOUN
fnp-3453	10	9	in	in	ADP
fnp-3453	10	10	immune	immune	NOUN
fnp-3453	10	11	,	,	PUNCT
fnp-3453	10	12	extracellular	extracellular	ADJ
fnp-3453	10	13	matrix	matrix	NOUN
fnp-3453	10	14	,	,	PUNCT
fnp-3453	10	15	vascular	vascular	ADJ
fnp-3453	10	16	,	,	PUNCT
fnp-3453	10	17	neuronal	neuronal	ADJ
fnp-3453	10	18	,	,	PUNCT
fnp-3453	10	19	and	and	CCONJ
fnp-3453	10	20	endocytosis	endocytosis	NOUN
fnp-3453	10	21	/	/	SYM
fnp-3453	10	22	exocytosis	exocytosis	NOUN
fnp-3453	10	23	categories	category	NOUN
fnp-3453	10	24	across	across	ADP
fnp-3453	10	25	all	all	DET
fnp-3453	10	26	groups	group	NOUN
fnp-3453	10	27	,	,	PUNCT
fnp-3453	10	28	suggesting	suggest	VERB
fnp-3453	10	29	the	the	DET
fnp-3453	10	30	sulcus	sulcus	NOUN
fnp-3453	10	31	has	have	VERB
fnp-3453	10	32	a	a	DET
fnp-3453	10	33	unique	unique	ADJ
fnp-3453	10	34	molecular	molecular	ADJ
fnp-3453	10	35	signature	signature	NOUN
fnp-3453	10	36	compared	compare	VERB
fnp-3453	10	37	to	to	ADP
fnp-3453	10	38	the	the	DET
fnp-3453	10	39	neighboring	neighboring	NOUN
fnp-3453	10	40	crest	crest	NOUN
fnp-3453	10	41	independent	independent	ADJ
fnp-3453	10	42	of	of	ADP
fnp-3453	10	43	pathology	pathology	NOUN
fnp-3453	10	44	.	.	PUNCT
fnp-3453	11	1	second	second	ADJ
fnp-3453	11	2	,	,	PUNCT
fnp-3453	11	3	individuals	individual	NOUN
fnp-3453	11	4	with	with	ADP
fnp-3453	11	5	a	a	DET
fnp-3453	11	6	history	history	NOUN
fnp-3453	11	7	of	of	ADP
fnp-3453	11	8	rhi	rhi	PROPN
fnp-3453	11	9	demonstrated	demonstrate	VERB
fnp-3453	11	10	impairment	impairment	NOUN
fnp-3453	11	11	in	in	ADP
fnp-3453	11	12	metabolic	metabolic	NOUN
fnp-3453	11	13	and	and	CCONJ
fnp-3453	11	14	mitochondrial	mitochondrial	ADJ
fnp-3453	11	15	related	relate	VERB
fnp-3453	11	16	processes	process	NOUN
fnp-3453	11	17	.	.	PUNCT
fnp-3453	12	1	finally	finally	ADV
fnp-3453	12	2	,	,	PUNCT
fnp-3453	12	3	in	in	ADP
fnp-3453	12	4	individuals	individual	NOUN
fnp-3453	12	5	with	with	ADP
fnp-3453	12	6	cte	cte	NOUN
fnp-3453	12	7	,	,	PUNCT
fnp-3453	12	8	we	we	PRON
fnp-3453	12	9	observed	observe	VERB
fnp-3453	12	10	impairment	impairment	NOUN
fnp-3453	12	11	of	of	ADP
fnp-3453	12	12	immune	immune	ADJ
fnp-3453	12	13	and	and	CCONJ
fnp-3453	12	14	phagocytic	phagocytic	ADJ
fnp-3453	12	15	related	relate	VERB
fnp-3453	12	16	processes	process	NOUN
fnp-3453	12	17	.	.	PUNCT
fnp-3453	13	1	overall	overall	ADV
fnp-3453	13	2	,	,	PUNCT
fnp-3453	13	3	this	this	DET
fnp-3453	13	4	work	work	NOUN
fnp-3453	13	5	provides	provide	VERB
fnp-3453	13	6	the	the	DET
fnp-3453	13	7	first	first	ADJ
fnp-3453	13	8	observation	observation	NOUN
fnp-3453	13	9	of	of	ADP
fnp-3453	13	10	biological	biological	ADJ
fnp-3453	13	11	processes	process	NOUN
fnp-3453	13	12	specifically	specifically	ADV
fnp-3453	13	13	altered	alter	VERB
fnp-3453	13	14	in	in	ADP
fnp-3453	13	15	the	the	DET
fnp-3453	13	16	sulcus	sulcus	NOUN
fnp-3453	13	17	that	that	PRON
fnp-3453	13	18	could	could	AUX
fnp-3453	13	19	be	be	AUX
fnp-3453	13	20	directly	directly	ADV
fnp-3453	13	21	implicated	implicate	VERB
fnp-3453	13	22	in	in	ADP
fnp-3453	13	23	cte	cte	NOUN
fnp-3453	13	24	pathogenesis	pathogenesis	NOUN
fnp-3453	13	25	and	and	CCONJ
fnp-3453	13	26	provide	provide	VERB
fnp-3453	13	27	novel	novel	ADJ
fnp-3453	13	28	targets	target	NOUN
fnp-3453	13	29	for	for	ADP
fnp-3453	13	30	biomarkers	biomarker	NOUN
fnp-3453	13	31	and	and	CCONJ
fnp-3453	13	32	therapies	therapy	NOUN
fnp-3453	13	33	.	.	PUNCT
fnp-3453	14	1	introduction	introduction	NOUN
fnp-3453	14	2	chronic	chronic	ADJ
fnp-3453	14	3	traumatic	traumatic	ADJ
fnp-3453	14	4	encephalopathy	encephalopathy	NOUN
fnp-3453	14	5	(	(	PUNCT
fnp-3453	14	6	cte	cte	NOUN
fnp-3453	14	7	)	)	PUNCT
fnp-3453	14	8	is	be	AUX
fnp-3453	14	9	a	a	DET
fnp-3453	14	10	progressive	progressive	ADJ
fnp-3453	14	11	neurodegenerative	neurodegenerative	ADJ
fnp-3453	14	12	disease	disease	NOUN
fnp-3453	14	13	found	find	VERB
fnp-3453	14	14	in	in	ADP
fnp-3453	14	15	individuals	individual	NOUN
fnp-3453	14	16	with	with	ADP
fnp-3453	14	17	a	a	DET
fnp-3453	14	18	history	history	NOUN
fnp-3453	14	19	of	of	ADP
fnp-3453	14	20	exposure	exposure	NOUN
fnp-3453	14	21	to	to	ADP
fnp-3453	14	22	repetitive	repetitive	ADJ
fnp-3453	14	23	head	head	NOUN
fnp-3453	14	24	impacts	impact	NOUN
fnp-3453	14	25	(	(	PUNCT
fnp-3453	14	26	rhi	rhi	NOUN
fnp-3453	14	27	)	)	PUNCT
fnp-3453	14	28	typically	typically	ADV
fnp-3453	14	29	received	receive	VERB
fnp-3453	14	30	through	through	ADP
fnp-3453	14	31	playing	play	VERB
fnp-3453	14	32	contact	contact	NOUN
fnp-3453	14	33	sports	sport	NOUN
fnp-3453	14	34	such	such	ADJ
fnp-3453	14	35	as	as	ADP
fnp-3453	14	36	american	american	ADJ
fnp-3453	14	37	football	football	PROPN
fnp-3453	14	38	,	,	PUNCT
fnp-3453	14	39	hockey	hockey	NOUN
fnp-3453	14	40	,	,	PUNCT
fnp-3453	14	41	soccer	soccer	NOUN
fnp-3453	14	42	,	,	PUNCT
fnp-3453	14	43	boxing	boxing	NOUN
fnp-3453	14	44	,	,	PUNCT
fnp-3453	14	45	or	or	CCONJ
fnp-3453	14	46	rugby	rugby	NOUN
fnp-3453	14	47	,	,	PUNCT
fnp-3453	14	48	or	or	CCONJ
fnp-3453	14	49	through	through	ADP
fnp-3453	14	50	military	military	ADJ
fnp-3453	14	51	service	service	NOUN
fnp-3453	14	52	-	-	PUNCT
fnp-3453	14	53	related	relate	VERB
fnp-3453	14	54	injuries	injury	NOUN
fnp-3453	14	55	like	like	ADP
fnp-3453	14	56	blasts	blast	NOUN
fnp-3453	14	57	[	[	X
fnp-3453	14	58	3	3	NUM
fnp-3453	14	59	,	,	PUNCT
fnp-3453	14	60	23	23	NUM
fnp-3453	14	61	,	,	PUNCT
fnp-3453	14	62	24	24	NUM
fnp-3453	14	63	]	]	PUNCT
fnp-3453	14	64	.	.	PUNCT
fnp-3453	15	1	currently	currently	ADV
fnp-3453	15	2	,	,	PUNCT
fnp-3453	15	3	cte	cte	PROPN
fnp-3453	15	4	can	can	AUX
fnp-3453	15	5	only	only	ADV
fnp-3453	15	6	be	be	AUX
fnp-3453	15	7	definitively	definitively	ADV
fnp-3453	15	8	diagnosed	diagnose	VERB
fnp-3453	15	9	after	after	ADP
fnp-3453	15	10	death	death	NOUN
fnp-3453	15	11	through	through	ADP
fnp-3453	15	12	neuropathologic	neuropathologic	ADJ
fnp-3453	15	13	autopsy	autopsy	ADJ
fnp-3453	15	14	.	.	PUNCT
fnp-3453	16	1	the	the	DET
fnp-3453	16	2	pathognomonic	pathognomonic	ADJ
fnp-3453	16	3	lesion	lesion	NOUN
fnp-3453	16	4	that	that	PRON
fnp-3453	16	5	defines	define	VERB
fnp-3453	16	6	the	the	DET
fnp-3453	16	7	disease	disease	NOUN
fnp-3453	16	8	consists	consist	VERB
fnp-3453	16	9	of	of	ADP
fnp-3453	16	10	perivascular	perivascular	ADJ
fnp-3453	16	11	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-3453	16	12	tau	tau	PROPN
fnp-3453	16	13	(	(	PUNCT
fnp-3453	16	14	p	p	PROPN
fnp-3453	16	15	-	-	PUNCT
fnp-3453	16	16	tau	tau	NOUN
fnp-3453	16	17	)	)	PUNCT
fnp-3453	16	18	found	find	VERB
fnp-3453	16	19	in	in	ADP
fnp-3453	16	20	neurons	neuron	NOUN
fnp-3453	16	21	and	and	CCONJ
fnp-3453	16	22	sometimes	sometimes	ADV
fnp-3453	16	23	astrocytes	astrocyte	NOUN
fnp-3453	16	24	,	,	PUNCT
fnp-3453	16	25	initially	initially	ADV
fnp-3453	16	26	at	at	ADP
fnp-3453	16	27	the	the	DET
fnp-3453	16	28	depths	depth	NOUN
fnp-3453	16	29	of	of	ADP
fnp-3453	16	30	the	the	DET
fnp-3453	16	31	cortical	cortical	ADJ
fnp-3453	16	32	sulcus	sulcus	NOUN
fnp-3453	16	33	in	in	ADP
fnp-3453	16	34	the	the	DET
fnp-3453	16	35	frontal	frontal	ADJ
fnp-3453	16	36	cortex	cortex	NOUN
fnp-3453	16	37	[	[	X
fnp-3453	16	38	3	3	NUM
fnp-3453	16	39	]	]	PUNCT
fnp-3453	16	40	.	.	PUNCT
fnp-3453	17	1	through	through	ADP
fnp-3453	17	2	computational	computational	ADJ
fnp-3453	17	3	modeling	modeling	NOUN
fnp-3453	17	4	and	and	CCONJ
fnp-3453	17	5	helmet	helmet	NOUN
fnp-3453	17	6	sensor	sensor	NOUN
fnp-3453	17	7	data	datum	NOUN
fnp-3453	17	8	,	,	PUNCT
fnp-3453	17	9	it	it	PRON
fnp-3453	17	10	was	be	AUX
fnp-3453	17	11	observed	observe	VERB
fnp-3453	17	12	that	that	SCONJ
fnp-3453	17	13	the	the	DET
fnp-3453	17	14	sulcus	sulcus	NOUN
fnp-3453	17	15	and	and	CCONJ
fnp-3453	17	16	blood	blood	NOUN
fnp-3453	17	17	vessels	vessel	NOUN
fnp-3453	17	18	receive	receive	VERB
fnp-3453	17	19	the	the	DET
fnp-3453	17	20	greatest	great	ADJ
fnp-3453	17	21	amount	amount	NOUN
fnp-3453	17	22	of	of	ADP
fnp-3453	17	23	damage	damage	NOUN
fnp-3453	17	24	after	after	ADP
fnp-3453	17	25	head	head	NOUN
fnp-3453	17	26	trauma	trauma	NOUN
fnp-3453	17	27	,	,	PUNCT
fnp-3453	17	28	directly	directly	ADV
fnp-3453	17	29	linking	link	VERB
fnp-3453	17	30	rhi	rhi	NOUN
fnp-3453	17	31	induced	induce	VERB
fnp-3453	17	32	trauma	trauma	NOUN
fnp-3453	17	33	to	to	PART
fnp-3453	17	34	cte	cte	VERB
fnp-3453	17	35	pathogenesis	pathogenesis	NOUN
fnp-3453	17	36	[	[	X
fnp-3453	17	37	11	11	NUM
fnp-3453	17	38	]	]	PUNCT
fnp-3453	17	39	.	.	PUNCT
fnp-3453	18	1	however	however	ADV
fnp-3453	18	2	,	,	PUNCT
fnp-3453	18	3	the	the	DET
fnp-3453	18	4	specific	specific	ADJ
fnp-3453	18	5	biological	biological	ADJ
fnp-3453	18	6	response	response	NOUN
fnp-3453	18	7	after	after	ADP
fnp-3453	18	8	trauma	trauma	NOUN
fnp-3453	18	9	that	that	PRON
fnp-3453	18	10	drives	drive	VERB
fnp-3453	18	11	cte	cte	PROPN
fnp-3453	18	12	pathology	pathology	PROPN
fnp-3453	18	13	is	be	AUX
fnp-3453	18	14	still	still	ADV
fnp-3453	18	15	unclear	unclear	ADJ
fnp-3453	18	16	.	.	PUNCT
fnp-3453	19	1	under	under	ADP
fnp-3453	19	2	normal	normal	ADJ
fnp-3453	19	3	circumstances	circumstance	NOUN
fnp-3453	19	4	,	,	PUNCT
fnp-3453	19	5	inflammation	inflammation	NOUN
fnp-3453	19	6	is	be	AUX
fnp-3453	19	7	a	a	DET
fnp-3453	19	8	necessary	necessary	ADJ
fnp-3453	19	9	part	part	NOUN
fnp-3453	19	10	of	of	ADP
fnp-3453	19	11	the	the	DET
fnp-3453	19	12	injury	injury	NOUN
fnp-3453	19	13	cascade	cascade	NOUN
fnp-3453	19	14	.	.	PUNCT
fnp-3453	20	1	in	in	ADP
fnp-3453	20	2	the	the	DET
fnp-3453	20	3	brain	brain	NOUN
fnp-3453	20	4	,	,	PUNCT
fnp-3453	20	5	neuroinflammation	neuroinflammation	NOUN
fnp-3453	20	6	has	have	AUX
fnp-3453	20	7	been	be	AUX
fnp-3453	20	8	observed	observe	VERB
fnp-3453	20	9	to	to	PART
fnp-3453	20	10	be	be	AUX
fnp-3453	20	11	necessary	necessary	ADJ
fnp-3453	20	12	for	for	ADP
fnp-3453	20	13	wound	wound	ADJ
fnp-3453	20	14	healing	healing	NOUN
fnp-3453	20	15	responses	response	NOUN
fnp-3453	20	16	after	after	ADP
fnp-3453	20	17	damage	damage	NOUN
fnp-3453	20	18	,	,	PUNCT
fnp-3453	20	19	triggering	trigger	VERB
fnp-3453	20	20	an	an	DET
fnp-3453	20	21	innate	innate	ADJ
fnp-3453	20	22	and	and	CCONJ
fnp-3453	20	23	adaptive	adaptive	ADJ
fnp-3453	20	24	immune	immune	ADJ
fnp-3453	20	25	response	response	NOUN
fnp-3453	20	26	to	to	PART
fnp-3453	20	27	fight	fight	VERB
fnp-3453	20	28	infectious	infectious	ADJ
fnp-3453	20	29	agents	agent	NOUN
fnp-3453	20	30	,	,	PUNCT
fnp-3453	20	31	and	and	CCONJ
fnp-3453	20	32	recruit	recruit	VERB
fnp-3453	20	33	beneficial	beneficial	ADJ
fnp-3453	20	34	immune	immune	ADJ
fnp-3453	20	35	cells	cell	NOUN
fnp-3453	20	36	to	to	ADP
fnp-3453	20	37	areas	area	NOUN
fnp-3453	20	38	of	of	ADP
fnp-3453	20	39	need	need	NOUN
fnp-3453	20	40	[	[	X
fnp-3453	20	41	6	6	NUM
fnp-3453	20	42	]	]	PUNCT
fnp-3453	20	43	.	.	PUNCT
fnp-3453	21	1	however	however	ADV
fnp-3453	21	2	,	,	PUNCT
fnp-3453	21	3	prolonged	prolonged	ADJ
fnp-3453	21	4	or	or	CCONJ
fnp-3453	21	5	chronic	chronic	ADJ
fnp-3453	21	6	inflammation	inflammation	NOUN
fnp-3453	21	7	can	can	AUX
fnp-3453	21	8	be	be	AUX
fnp-3453	21	9	harmful	harmful	ADJ
fnp-3453	21	10	and	and	CCONJ
fnp-3453	21	11	can	can	AUX
fnp-3453	21	12	result	result	VERB
fnp-3453	21	13	in	in	ADP
fnp-3453	21	14	tissue	tissue	NOUN
fnp-3453	21	15	damage	damage	NOUN
fnp-3453	21	16	and	and	CCONJ
fnp-3453	21	17	long	long	ADJ
fnp-3453	21	18	-	-	PUNCT
fnp-3453	21	19	term	term	NOUN
fnp-3453	21	20	pathology	pathology	NOUN
fnp-3453	21	21	.	.	PUNCT
fnp-3453	22	1	rhi	rhi	PROPN
fnp-3453	22	2	has	have	AUX
fnp-3453	22	3	been	be	AUX
fnp-3453	22	4	shown	show	VERB
fnp-3453	22	5	to	to	PART
fnp-3453	22	6	induce	induce	VERB
fnp-3453	22	7	a	a	DET
fnp-3453	22	8	chronic	chronic	ADJ
fnp-3453	22	9	neuroinflammatory	neuroinflammatory	NOUN
fnp-3453	22	10	environment	environment	NOUN
fnp-3453	22	11	in	in	ADP
fnp-3453	22	12	both	both	PRON
fnp-3453	22	13	mouse	mouse	NOUN
fnp-3453	22	14	and	and	CCONJ
fnp-3453	22	15	human	human	ADJ
fnp-3453	22	16	studies	study	NOUN
fnp-3453	22	17	[	[	X
fnp-3453	22	18	9	9	NUM
fnp-3453	22	19	,	,	PUNCT
fnp-3453	22	20	10	10	NUM
fnp-3453	22	21	,	,	PUNCT
fnp-3453	22	22	32	32	NUM
fnp-3453	22	23	]	]	PUNCT
fnp-3453	22	24	.	.	PUNCT
fnp-3453	23	1	additionally	additionally	ADV
fnp-3453	23	2	,	,	PUNCT
fnp-3453	23	3	previous	previous	ADJ
fnp-3453	23	4	work	work	NOUN
fnp-3453	23	5	from	from	ADP
fnp-3453	23	6	our	our	PRON
fnp-3453	23	7	laboratory	laboratory	NOUN
fnp-3453	23	8	has	have	AUX
fnp-3453	23	9	demonstrated	demonstrate	VERB
fnp-3453	23	10	that	that	SCONJ
fnp-3453	23	11	elevated	elevate	VERB
fnp-3453	23	12	microglial	microglial	ADJ
fnp-3453	23	13	recruitment	recruitment	NOUN
fnp-3453	23	14	via	via	ADP
fnp-3453	23	15	the	the	DET
fnp-3453	23	16	chemokine	chemokine	ADJ
fnp-3453	23	17	ccl2	ccl2	NOUN
fnp-3453	23	18	,	,	PUNCT
fnp-3453	23	19	and	and	CCONJ
fnp-3453	23	20	glial	glial	ADJ
fnp-3453	23	21	activation	activation	NOUN
fnp-3453	23	22	was	be	AUX
fnp-3453	23	23	related	relate	VERB
fnp-3453	23	24	to	to	ADP
fnp-3453	23	25	greater	great	ADJ
fnp-3453	23	26	years	year	NOUN
fnp-3453	23	27	playing	play	VERB
fnp-3453	23	28	contact	contact	NOUN
fnp-3453	23	29	sports	sport	NOUN
fnp-3453	23	30	and	and	CCONJ
fnp-3453	23	31	is	be	AUX
fnp-3453	23	32	a	a	DET
fnp-3453	23	33	prominent	prominent	ADJ
fnp-3453	23	34	feature	feature	NOUN
fnp-3453	23	35	in	in	ADP
fnp-3453	23	36	cte	cte	NOUN
fnp-3453	24	1	[	[	X
fnp-3453	24	2	4	4	NUM
fnp-3453	24	3	,	,	PUNCT
fnp-3453	24	4	7	7	NUM
fnp-3453	24	5	]	]	PUNCT
fnp-3453	24	6	.	.	PUNCT
fnp-3453	25	1	we	we	PRON
fnp-3453	25	2	observed	observe	VERB
fnp-3453	25	3	that	that	SCONJ
fnp-3453	25	4	microglia	microglia	ADJ
fnp-3453	25	5	-	-	PUNCT
fnp-3453	25	6	mediated	mediate	VERB
fnp-3453	25	7	neuroinflammation	neuroinflammation	NOUN
fnp-3453	25	8	may	may	AUX
fnp-3453	25	9	exist	exist	VERB
fnp-3453	25	10	in	in	ADP
fnp-3453	25	11	a	a	DET
fnp-3453	25	12	feedback	feedback	NOUN
fnp-3453	25	13	loop	loop	NOUN
fnp-3453	25	14	with	with	ADP
fnp-3453	25	15	p	p	PROPN
fnp-3453	25	16	-	-	PUNCT
fnp-3453	25	17	tau	tau	PROPN
fnp-3453	25	18	pathology	pathology	NOUN
fnp-3453	25	19	.	.	PUNCT
fnp-3453	26	1	neuroinflammation	neuroinflammation	NOUN
fnp-3453	26	2	induces	induce	VERB
fnp-3453	26	3	p	p	PROPN
fnp-3453	26	4	-	-	PUNCT
fnp-3453	26	5	tau	tau	NOUN
fnp-3453	26	6	deposition	deposition	NOUN
fnp-3453	26	7	,	,	PUNCT
fnp-3453	26	8	which	which	PRON
fnp-3453	26	9	in	in	ADP
fnp-3453	26	10	turn	turn	NOUN
fnp-3453	26	11	induces	induce	VERB
fnp-3453	26	12	more	more	ADJ
fnp-3453	26	13	neuroinflammation	neuroinflammation	NOUN
fnp-3453	26	14	leading	lead	VERB
fnp-3453	26	15	to	to	ADP
fnp-3453	26	16	a	a	DET
fnp-3453	26	17	vicious	vicious	ADJ
fnp-3453	26	18	cycle	cycle	NOUN
fnp-3453	26	19	,	,	PUNCT
fnp-3453	26	20	similar	similar	ADJ
fnp-3453	26	21	to	to	ADP
fnp-3453	26	22	the	the	DET
fnp-3453	26	23	inflammatory	inflammatory	ADJ
fnp-3453	26	24	cascade	cascade	NOUN
fnp-3453	26	25	hypothesis	hypothesis	NOUN
fnp-3453	26	26	in	in	ADP
fnp-3453	26	27	alzheimer	alzheimer	PROPN
fnp-3453	26	28	’s	’s	PART
fnp-3453	26	29	disease	disease	NOUN
fnp-3453	26	30	(	(	PUNCT
fnp-3453	26	31	ad	ad	NOUN
fnp-3453	26	32	)	)	PUNCT
fnp-3453	27	1	[	[	X
fnp-3453	27	2	12	12	NUM
fnp-3453	27	3	,	,	PUNCT
fnp-3453	27	4	16	16	NUM
fnp-3453	27	5	]	]	PUNCT
fnp-3453	27	6	.	.	PUNCT
fnp-3453	28	1	however	however	ADV
fnp-3453	28	2	,	,	PUNCT
fnp-3453	28	3	the	the	DET
fnp-3453	28	4	concept	concept	NOUN
fnp-3453	28	5	of	of	ADP
fnp-3453	28	6	neuroinflammation	neuroinflammation	NOUN
fnp-3453	28	7	is	be	AUX
fnp-3453	28	8	broad	broad	ADJ
fnp-3453	28	9	,	,	PUNCT
fnp-3453	28	10	encompassing	encompass	VERB
fnp-3453	28	11	inflammatory	inflammatory	ADJ
fnp-3453	28	12	,	,	PUNCT
fnp-3453	28	13	anti	anti	ADJ
fnp-3453	28	14	-	-	ADJ
fnp-3453	28	15	inflammatory	inflammatory	ADJ
fnp-3453	28	16	,	,	PUNCT
fnp-3453	28	17	senescent	senescent	NOUN
fnp-3453	28	18	,	,	PUNCT
fnp-3453	28	19	and	and	CCONJ
fnp-3453	28	20	immunoregulatory	immunoregulatory	ADJ
fnp-3453	28	21	features	feature	VERB
fnp-3453	28	22	that	that	SCONJ
fnp-3453	28	23	previous	previous	ADJ
fnp-3453	28	24	histology	histology	NOUN
fnp-3453	28	25	-	-	PUNCT
fnp-3453	28	26	based	base	VERB
fnp-3453	28	27	studies	study	NOUN
fnp-3453	28	28	were	be	AUX
fnp-3453	28	29	unable	unable	ADJ
fnp-3453	28	30	to	to	PART
fnp-3453	28	31	easily	easily	ADV
fnp-3453	28	32	segregate	segregate	VERB
fnp-3453	28	33	[	[	PUNCT
fnp-3453	28	34	6	6	NUM
fnp-3453	28	35	]	]	PUNCT
fnp-3453	28	36	.	.	PUNCT
fnp-3453	29	1	therefore	therefore	ADV
fnp-3453	29	2	,	,	PUNCT
fnp-3453	29	3	there	there	PRON
fnp-3453	29	4	is	be	VERB
fnp-3453	29	5	a	a	DET
fnp-3453	29	6	critical	critical	ADJ
fnp-3453	29	7	need	need	NOUN
fnp-3453	29	8	to	to	PART
fnp-3453	29	9	understand	understand	VERB
fnp-3453	29	10	the	the	DET
fnp-3453	29	11	individual	individual	ADJ
fnp-3453	29	12	inflammatory	inflammatory	ADJ
fnp-3453	29	13	phenotypes	phenotype	NOUN
fnp-3453	29	14	that	that	PRON
fnp-3453	29	15	emerge	emerge	VERB
fnp-3453	29	16	during	during	ADP
fnp-3453	29	17	rhi	rhi	PROPN
fnp-3453	29	18	to	to	PART
fnp-3453	29	19	have	have	VERB
fnp-3453	29	20	more	more	ADV
fnp-3453	29	21	complete	complete	ADJ
fnp-3453	29	22	insight	insight	NOUN
fnp-3453	29	23	into	into	ADP
fnp-3453	29	24	the	the	DET
fnp-3453	29	25	various	various	ADJ
fnp-3453	29	26	mechanisms	mechanism	NOUN
fnp-3453	29	27	which	which	PRON
fnp-3453	29	28	may	may	AUX
fnp-3453	29	29	directly	directly	ADV
fnp-3453	29	30	result	result	VERB
fnp-3453	29	31	in	in	ADP
fnp-3453	29	32	cte	cte	NOUN
fnp-3453	29	33	pathogenesis	pathogenesis	NOUN
fnp-3453	29	34	.	.	PUNCT
fnp-3453	30	1	to	to	PART
fnp-3453	30	2	help	help	VERB
fnp-3453	30	3	fill	fill	VERB
fnp-3453	30	4	in	in	ADP
fnp-3453	30	5	knowledge	knowledge	NOUN
fnp-3453	30	6	gaps	gap	NOUN
fnp-3453	30	7	,	,	PUNCT
fnp-3453	30	8	high	high	ADJ
fnp-3453	30	9	level	level	NOUN
fnp-3453	30	10	bioinformatic	bioinformatic	ADJ
fnp-3453	30	11	analyses	analysis	NOUN
fnp-3453	30	12	are	be	AUX
fnp-3453	30	13	needed	need	VERB
fnp-3453	30	14	.	.	PUNCT
fnp-3453	31	1	previous	previous	ADJ
fnp-3453	31	2	studies	study	NOUN
fnp-3453	31	3	have	have	AUX
fnp-3453	31	4	demonstrated	demonstrate	VERB
fnp-3453	31	5	that	that	SCONJ
fnp-3453	31	6	high	high	ADJ
fnp-3453	31	7	throughput	throughput	NOUN
fnp-3453	31	8	genomic	genomic	NOUN
fnp-3453	31	9	techniques	technique	NOUN
fnp-3453	31	10	and	and	CCONJ
fnp-3453	31	11	bioinformatic	bioinformatic	ADJ
fnp-3453	31	12	pipelines	pipeline	NOUN
fnp-3453	31	13	are	be	AUX
fnp-3453	31	14	an	an	DET
fnp-3453	31	15	optimal	optimal	ADJ
fnp-3453	31	16	method	method	NOUN
fnp-3453	31	17	to	to	PART
fnp-3453	31	18	investigate	investigate	VERB
fnp-3453	31	19	large	large	ADJ
fnp-3453	31	20	scale	scale	NOUN
fnp-3453	31	21	changes	change	NOUN
fnp-3453	31	22	in	in	ADP
fnp-3453	31	23	the	the	DET
fnp-3453	31	24	brain	brain	NOUN
fnp-3453	31	25	and	and	CCONJ
fnp-3453	31	26	determine	determine	VERB
fnp-3453	31	27	specific	specific	ADJ
fnp-3453	31	28	pathways	pathway	NOUN
fnp-3453	31	29	and	and	CCONJ
fnp-3453	31	30	effects	effect	NOUN
fnp-3453	31	31	in	in	ADP
fnp-3453	31	32	a	a	DET
fnp-3453	31	33	more	more	ADV
fnp-3453	31	34	efficient	efficient	ADJ
fnp-3453	31	35	manner	manner	NOUN
fnp-3453	32	1	[	[	X
fnp-3453	32	2	1	1	NUM
fnp-3453	32	3	,	,	PUNCT
fnp-3453	32	4	17	17	NUM
fnp-3453	32	5	]	]	PUNCT
fnp-3453	32	6	.	.	PUNCT
fnp-3453	33	1	herein	herein	NOUN
fnp-3453	33	2	,	,	PUNCT
fnp-3453	33	3	we	we	PRON
fnp-3453	33	4	utilized	utilize	VERB
fnp-3453	33	5	bulk	bulk	ADJ
fnp-3453	33	6	tissue	tissue	NOUN
fnp-3453	33	7	rna	rna	NOUN
fnp-3453	33	8	-	-	PUNCT
fnp-3453	33	9	sequencing	sequence	VERB
fnp-3453	33	10	targeted	target	VERB
fnp-3453	33	11	to	to	ADP
fnp-3453	33	12	cortical	cortical	ADJ
fnp-3453	33	13	anatomy	anatomy	NOUN
fnp-3453	33	14	,	,	PUNCT
fnp-3453	33	15	in	in	ADP
fnp-3453	33	16	order	order	NOUN
fnp-3453	33	17	to	to	PART
fnp-3453	33	18	investigate	investigate	VERB
fnp-3453	33	19	the	the	DET
fnp-3453	33	20	spectrum	spectrum	NOUN
fnp-3453	33	21	of	of	ADP
fnp-3453	33	22	inflammatory	inflammatory	ADJ
fnp-3453	33	23	and	and	CCONJ
fnp-3453	33	24	neurodegenerative	neurodegenerative	ADJ
fnp-3453	33	25	phenotypes	phenotype	NOUN
fnp-3453	33	26	that	that	PRON
fnp-3453	33	27	occur	occur	VERB
fnp-3453	33	28	as	as	ADP
fnp-3453	33	29	a	a	DET
fnp-3453	33	30	result	result	NOUN
fnp-3453	33	31	of	of	ADP
fnp-3453	33	32	rhi	rhi	PROPN
fnp-3453	33	33	and	and	CCONJ
fnp-3453	33	34	during	during	ADP
fnp-3453	33	35	early	early	ADJ
fnp-3453	33	36	stage	stage	NOUN
fnp-3453	33	37	cte	cte	NOUN
fnp-3453	33	38	.	.	PUNCT
fnp-3453	34	1	as	as	SCONJ
fnp-3453	34	2	the	the	DET
fnp-3453	34	3	earliest	early	ADJ
fnp-3453	34	4	neuropathologic	neuropathologic	ADJ
fnp-3453	34	5	feature	feature	NOUN
fnp-3453	34	6	of	of	ADP
fnp-3453	34	7	cte	cte	NOUN
fnp-3453	34	8	is	be	AUX
fnp-3453	34	9	p	p	PROPN
fnp-3453	34	10	-	-	PUNCT
fnp-3453	34	11	tau	tau	PROPN
fnp-3453	34	12	pathology	pathology	NOUN
fnp-3453	34	13	found	find	VERB
fnp-3453	34	14	at	at	ADP
fnp-3453	34	15	the	the	DET
fnp-3453	34	16	depth	depth	NOUN
fnp-3453	34	17	of	of	ADP
fnp-3453	34	18	the	the	DET
fnp-3453	34	19	cortical	cortical	ADJ
fnp-3453	34	20	sulcus	sulcus	NOUN
fnp-3453	34	21	,	,	PUNCT
fnp-3453	34	22	we	we	PRON
fnp-3453	34	23	chose	choose	VERB
fnp-3453	34	24	to	to	PART
fnp-3453	34	25	examine	examine	VERB
fnp-3453	34	26	what	what	PRON
fnp-3453	34	27	genetic	genetic	ADJ
fnp-3453	34	28	changes	change	NOUN
fnp-3453	34	29	occur	occur	VERB
fnp-3453	34	30	specifically	specifically	ADV
fnp-3453	34	31	in	in	ADP
fnp-3453	34	32	the	the	DET
fnp-3453	34	33	sulcus	sulcus	NOUN
fnp-3453	34	34	compared	compare	VERB
fnp-3453	34	35	to	to	ADP
fnp-3453	34	36	the	the	DET
fnp-3453	34	37	neighboring	neighboring	ADJ
fnp-3453	34	38	gyral	gyral	ADJ
fnp-3453	34	39	crest	crest	NOUN
fnp-3453	34	40	.	.	PUNCT
fnp-3453	35	1	by	by	ADP
fnp-3453	35	2	directly	directly	ADV
fnp-3453	35	3	comparing	compare	VERB
fnp-3453	35	4	between	between	ADP
fnp-3453	35	5	the	the	DET
fnp-3453	35	6	sulcus	sulcus	NOUN
fnp-3453	35	7	and	and	CCONJ
fnp-3453	35	8	crest	crest	NOUN
fnp-3453	35	9	within	within	ADP
fnp-3453	35	10	each	each	DET
fnp-3453	35	11	case	case	NOUN
fnp-3453	35	12	,	,	PUNCT
fnp-3453	35	13	we	we	PRON
fnp-3453	35	14	will	will	AUX
fnp-3453	35	15	have	have	VERB
fnp-3453	35	16	unique	unique	ADJ
fnp-3453	35	17	insights	insight	NOUN
fnp-3453	35	18	into	into	ADP
fnp-3453	35	19	which	which	PRON
fnp-3453	35	20	genes	gene	NOUN
fnp-3453	35	21	or	or	CCONJ
fnp-3453	35	22	biological	biological	ADJ
fnp-3453	35	23	processes	process	NOUN
fnp-3453	35	24	are	be	AUX
fnp-3453	35	25	specifically	specifically	ADV
fnp-3453	35	26	altered	alter	VERB
fnp-3453	35	27	in	in	ADP
fnp-3453	35	28	the	the	DET
fnp-3453	35	29	sulcus	sulcus	NOUN
fnp-3453	35	30	as	as	SCONJ
fnp-3453	35	31	opposed	oppose	VERB
fnp-3453	35	32	to	to	ADP
fnp-3453	35	33	genes	gene	NOUN
fnp-3453	35	34	that	that	PRON
fnp-3453	35	35	are	be	AUX
fnp-3453	35	36	part	part	NOUN
fnp-3453	35	37	of	of	ADP
fnp-3453	35	38	a	a	DET
fnp-3453	35	39	more	more	ADJ
fnp-3453	35	40	tissue	tissue	NOUN
fnp-3453	35	41	wide	wide	ADJ
fnp-3453	35	42	response	response	NOUN
fnp-3453	35	43	.	.	PUNCT
fnp-3453	36	1	we	we	PRON
fnp-3453	36	2	will	will	AUX
fnp-3453	36	3	utilize	utilize	VERB
fnp-3453	36	4	three	three	NUM
fnp-3453	36	5	separate	separate	ADJ
fnp-3453	36	6	groups	group	NOUN
fnp-3453	36	7	,	,	PUNCT
fnp-3453	36	8	individuals	individual	NOUN
fnp-3453	36	9	without	without	ADP
fnp-3453	36	10	any	any	DET
fnp-3453	36	11	rhi	rhi	NOUN
fnp-3453	36	12	or	or	CCONJ
fnp-3453	36	13	cte	cte	PROPN
fnp-3453	36	14	(	(	PUNCT
fnp-3453	36	15	controls	control	NOUN
fnp-3453	36	16	)	)	PUNCT
fnp-3453	36	17	,	,	PUNCT
fnp-3453	36	18	individuals	individual	NOUN
fnp-3453	36	19	with	with	ADP
fnp-3453	36	20	rhi	rhi	PROPN
fnp-3453	36	21	but	but	CCONJ
fnp-3453	36	22	no	no	DET
fnp-3453	36	23	cte	cte	NOUN
fnp-3453	36	24	(	(	PUNCT
fnp-3453	36	25	rhi	rhi	PROPN
fnp-3453	36	26	)	)	PUNCT
fnp-3453	36	27	,	,	PUNCT
fnp-3453	36	28	and	and	CCONJ
fnp-3453	36	29	individuals	individual	NOUN
fnp-3453	36	30	with	with	ADP
fnp-3453	36	31	early	early	ADJ
fnp-3453	36	32	stage	stage	NOUN
fnp-3453	36	33	cte	cte	NOUN
fnp-3453	36	34	(	(	PUNCT
fnp-3453	36	35	cte	cte	PROPN
fnp-3453	36	36	)	)	PUNCT
fnp-3453	36	37	.	.	PUNCT
fnp-3453	37	1	comparison	comparison	NOUN
fnp-3453	37	2	of	of	ADP
fnp-3453	37	3	these	these	DET
fnp-3453	37	4	three	three	NUM
fnp-3453	37	5	groups	group	NOUN
fnp-3453	37	6	will	will	AUX
fnp-3453	37	7	allow	allow	VERB
fnp-3453	37	8	direct	direct	ADJ
fnp-3453	37	9	analysis	analysis	NOUN
fnp-3453	37	10	of	of	ADP
fnp-3453	37	11	different	different	ADJ
fnp-3453	37	12	stages	stage	NOUN
fnp-3453	37	13	of	of	ADP
fnp-3453	37	14	disease	disease	NOUN
fnp-3453	37	15	.	.	PUNCT
fnp-3453	38	1	furthermore	furthermore	ADV
fnp-3453	38	2	,	,	PUNCT
fnp-3453	38	3	the	the	DET
fnp-3453	38	4	results	result	NOUN
fnp-3453	38	5	will	will	AUX
fnp-3453	38	6	provide	provide	VERB
fnp-3453	38	7	new	new	ADJ
fnp-3453	38	8	understandings	understanding	NOUN
fnp-3453	38	9	and	and	CCONJ
fnp-3453	38	10	insight	insight	NOUN
fnp-3453	38	11	into	into	ADP
fnp-3453	38	12	what	what	PRON
fnp-3453	38	13	genes	gene	NOUN
fnp-3453	38	14	and	and	CCONJ
fnp-3453	38	15	biological	biological	ADJ
fnp-3453	38	16	processes	process	NOUN
fnp-3453	38	17	might	might	AUX
fnp-3453	38	18	be	be	AUX
fnp-3453	38	19	directly	directly	ADV
fnp-3453	38	20	related	relate	VERB
fnp-3453	38	21	to	to	ADP
fnp-3453	38	22	initial	initial	ADJ
fnp-3453	38	23	cte	cte	PROPN
fnp-3453	38	24	p	p	PROPN
fnp-3453	38	25	-	-	PUNCT
fnp-3453	38	26	tau	tau	PROPN
fnp-3453	38	27	deposition	deposition	NOUN
fnp-3453	38	28	as	as	SCONJ
fnp-3453	38	29	opposed	oppose	VERB
fnp-3453	38	30	to	to	ADP
fnp-3453	38	31	a	a	DET
fnp-3453	38	32	general	general	ADJ
fnp-3453	38	33	cns	cns	NOUN
fnp-3453	38	34	response	response	NOUN
fnp-3453	38	35	to	to	PART
fnp-3453	38	36	trauma	trauma	VERB
fnp-3453	38	37	.	.	PUNCT
fnp-3453	39	1	finally	finally	ADV
fnp-3453	39	2	,	,	PUNCT
fnp-3453	39	3	genes	gene	NOUN
fnp-3453	39	4	that	that	PRON
fnp-3453	39	5	are	be	AUX
fnp-3453	39	6	found	find	VERB
fnp-3453	39	7	to	to	PART
fnp-3453	39	8	be	be	AUX
fnp-3453	39	9	specific	specific	ADJ
fnp-3453	39	10	to	to	PART
fnp-3453	39	11	cte	cte	VERB
fnp-3453	39	12	related	related	ADJ
fnp-3453	39	13	pathology	pathology	NOUN
fnp-3453	39	14	will	will	AUX
fnp-3453	39	15	become	become	VERB
fnp-3453	39	16	targets	target	NOUN
fnp-3453	39	17	for	for	ADP
fnp-3453	39	18	future	future	ADJ
fnp-3453	39	19	biomarker	biomarker	NOUN
fnp-3453	39	20	or	or	CCONJ
fnp-3453	39	21	therapeutic	therapeutic	ADJ
fnp-3453	39	22	intervention	intervention	NOUN
fnp-3453	39	23	studies	study	NOUN
fnp-3453	39	24	.	.	PUNCT
fnp-3453	40	1	methods	method	NOUN
fnp-3453	40	2	subjects	subject	VERB
fnp-3453	40	3	a	a	DET
fnp-3453	40	4	convenience	convenience	NOUN
fnp-3453	40	5	sample	sample	NOUN
fnp-3453	40	6	of	of	ADP
fnp-3453	40	7	15	15	NUM
fnp-3453	40	8	brain	brain	NOUN
fnp-3453	40	9	donors	donor	NOUN
fnp-3453	40	10	with	with	ADP
fnp-3453	40	11	a	a	DET
fnp-3453	40	12	history	history	NOUN
fnp-3453	40	13	of	of	ADP
fnp-3453	40	14	rhi	rhi	PROPN
fnp-3453	40	15	exposure	exposure	NOUN
fnp-3453	40	16	from	from	ADP
fnp-3453	40	17	contact	contact	NOUN
fnp-3453	40	18	sports	sport	NOUN
fnp-3453	40	19	were	be	AUX
fnp-3453	40	20	selected	select	VERB
fnp-3453	40	21	from	from	ADP
fnp-3453	40	22	the	the	DET
fnp-3453	40	23	understanding	understanding	ADJ
fnp-3453	40	24	neurological	neurological	ADJ
fnp-3453	40	25	injury	injury	NOUN
fnp-3453	40	26	and	and	CCONJ
fnp-3453	40	27	traumatic	traumatic	ADJ
fnp-3453	40	28	encephalopathy	encephalopathy	NOUN
fnp-3453	40	29	(	(	PUNCT
fnp-3453	40	30	unite	unite	NOUN
fnp-3453	40	31	)	)	PUNCT
fnp-3453	40	32	brain	brain	NOUN
fnp-3453	40	33	bank	bank	NOUN
fnp-3453	40	34	.	.	PUNCT
fnp-3453	41	1	selection	selection	NOUN
fnp-3453	41	2	was	be	AUX
fnp-3453	41	3	based	base	VERB
fnp-3453	41	4	on	on	ADP
fnp-3453	41	5	availability	availability	NOUN
fnp-3453	41	6	of	of	ADP
fnp-3453	41	7	frozen	frozen	ADJ
fnp-3453	41	8	frontal	frontal	ADJ
fnp-3453	41	9	cortex	cortex	NOUN
fnp-3453	41	10	tissue	tissue	NOUN
fnp-3453	41	11	and	and	CCONJ
fnp-3453	41	12	if	if	SCONJ
fnp-3453	41	13	the	the	DET
fnp-3453	41	14	cases	case	NOUN
fnp-3453	41	15	were	be	AUX
fnp-3453	41	16	male	male	ADJ
fnp-3453	41	17	and	and	CCONJ
fnp-3453	41	18	between	between	ADP
fnp-3453	41	19	the	the	DET
fnp-3453	41	20	ages	age	NOUN
fnp-3453	41	21	of	of	ADP
fnp-3453	41	22	35	35	NUM
fnp-3453	41	23	-	-	SYM
fnp-3453	41	24	65	65	NUM
fnp-3453	41	25	years	year	NOUN
fnp-3453	41	26	old	old	ADJ
fnp-3453	41	27	.	.	PUNCT
fnp-3453	42	1	samples	sample	NOUN
fnp-3453	42	2	were	be	AUX
fnp-3453	42	3	excluded	exclude	VERB
fnp-3453	42	4	from	from	ADP
fnp-3453	42	5	the	the	DET
fnp-3453	42	6	study	study	NOUN
fnp-3453	42	7	if	if	SCONJ
fnp-3453	42	8	they	they	PRON
fnp-3453	42	9	carried	carry	VERB
fnp-3453	42	10	a	a	DET
fnp-3453	42	11	neuropathologic	neuropathologic	ADJ
fnp-3453	42	12	diagnosis	diagnosis	NOUN
fnp-3453	42	13	of	of	ADP
fnp-3453	42	14	ad	ad	NOUN
fnp-3453	42	15	,	,	PUNCT
fnp-3453	42	16	neocortical	neocortical	ADJ
fnp-3453	42	17	lewy	lewy	ADJ
fnp-3453	42	18	bodies	body	NOUN
fnp-3453	42	19	,	,	PUNCT
fnp-3453	42	20	frontotemporal	frontotemporal	ADJ
fnp-3453	42	21	lobar	lobar	ADJ
fnp-3453	42	22	degeneration	degeneration	NOUN
fnp-3453	42	23	(	(	PUNCT
fnp-3453	42	24	ftld	ftld	ADJ
fnp-3453	42	25	)	)	PUNCT
fnp-3453	42	26	,	,	PUNCT
fnp-3453	42	27	or	or	CCONJ
fnp-3453	42	28	motor	motor	NOUN
fnp-3453	42	29	neuron	neuron	PROPN
fnp-3453	42	30	disease	disease	PROPN
fnp-3453	42	31	(	(	PUNCT
fnp-3453	42	32	mnd	mnd	PROPN
fnp-3453	42	33	)	)	PUNCT
fnp-3453	42	34	based	base	VERB
fnp-3453	42	35	on	on	ADP
fnp-3453	42	36	established	establish	VERB
fnp-3453	42	37	neuropathologic	neuropathologic	ADJ
fnp-3453	42	38	criteria	criterion	NOUN
fnp-3453	42	39	for	for	ADP
fnp-3453	42	40	each	each	DET
fnp-3453	42	41	disease	disease	NOUN
fnp-3453	43	1	[	[	X
fnp-3453	43	2	19	19	NUM
fnp-3453	43	3	,	,	PUNCT
fnp-3453	43	4	20	20	NUM
fnp-3453	43	5	,	,	PUNCT
fnp-3453	43	6	25	25	NUM
fnp-3453	43	7	,	,	PUNCT
fnp-3453	43	8	26	26	NUM
fnp-3453	43	9	]	]	PUNCT
fnp-3453	43	10	.	.	PUNCT
fnp-3453	44	1	an	an	DET
fnp-3453	44	2	additional	additional	ADJ
fnp-3453	44	3	6	6	NUM
fnp-3453	44	4	donors	donor	NOUN
fnp-3453	44	5	were	be	AUX
fnp-3453	44	6	obtained	obtain	VERB
fnp-3453	44	7	from	from	ADP
fnp-3453	44	8	the	the	DET
fnp-3453	44	9	national	national	ADJ
fnp-3453	44	10	post	post	ADJ
fnp-3453	44	11	-	-	ADJ
fnp-3453	44	12	traumatic	traumatic	ADJ
fnp-3453	44	13	stress	stress	NOUN
fnp-3453	44	14	disorder	disorder	NOUN
fnp-3453	44	15	(	(	PUNCT
fnp-3453	44	16	ptsd	ptsd	PROPN
fnp-3453	44	17	)	)	PUNCT
fnp-3453	44	18	brain	brain	NOUN
fnp-3453	44	19	bank	bank	NOUN
fnp-3453	44	20	(	(	PUNCT
fnp-3453	44	21	national	national	ADJ
fnp-3453	44	22	center	center	NOUN
fnp-3453	44	23	for	for	ADP
fnp-3453	44	24	ptsd	ptsd	PROPN
fnp-3453	44	25	,	,	PUNCT
fnp-3453	44	26	va	va	PROPN
fnp-3453	44	27	boston	boston	PROPN
fnp-3453	44	28	healthcare	healthcare	PROPN
fnp-3453	44	29	system	system	PROPN
fnp-3453	44	30	,	,	PUNCT
fnp-3453	44	31	boston	boston	PROPN
fnp-3453	44	32	ma	ma	PROPN
fnp-3453	44	33	)	)	PUNCT
fnp-3453	44	34	.	.	PUNCT
fnp-3453	45	1	these	these	DET
fnp-3453	45	2	6	6	NUM
fnp-3453	45	3	donors	donor	NOUN
fnp-3453	45	4	were	be	AUX
fnp-3453	45	5	selected	select	VERB
fnp-3453	45	6	from	from	ADP
fnp-3453	45	7	a	a	DET
fnp-3453	45	8	group	group	NOUN
fnp-3453	45	9	that	that	PRON
fnp-3453	45	10	lacked	lack	VERB
fnp-3453	45	11	a	a	DET
fnp-3453	45	12	history	history	NOUN
fnp-3453	45	13	of	of	ADP
fnp-3453	45	14	rhi	rhi	NOUN
fnp-3453	45	15	,	,	PUNCT
fnp-3453	45	16	did	do	AUX
fnp-3453	45	17	not	not	PART
fnp-3453	45	18	have	have	VERB
fnp-3453	45	19	evidence	evidence	NOUN
fnp-3453	45	20	of	of	ADP
fnp-3453	45	21	a	a	DET
fnp-3453	45	22	neurodegenerative	neurodegenerative	ADJ
fnp-3453	45	23	disease	disease	NOUN
fnp-3453	45	24	at	at	ADP
fnp-3453	45	25	autopsy	autopsy	ADJ
fnp-3453	45	26	,	,	PUNCT
fnp-3453	45	27	and	and	CCONJ
fnp-3453	45	28	were	be	AUX
fnp-3453	45	29	not	not	PART
fnp-3453	45	30	diagnosed	diagnose	VERB
fnp-3453	45	31	with	with	ADP
fnp-3453	45	32	ptsd	ptsd	NOUN
fnp-3453	45	33	in	in	ADP
fnp-3453	45	34	life	life	NOUN
fnp-3453	45	35	.	.	PUNCT
fnp-3453	46	1	samples	sample	NOUN
fnp-3453	46	2	were	be	AUX
fnp-3453	46	3	grouped	group	VERB
fnp-3453	46	4	into	into	ADP
fnp-3453	46	5	three	three	NUM
fnp-3453	46	6	categories	category	NOUN
fnp-3453	46	7	:	:	PUNCT
fnp-3453	46	8	6	6	NUM
fnp-3453	46	9	cases	case	NOUN
fnp-3453	46	10	with	with	ADP
fnp-3453	46	11	no	no	DET
fnp-3453	46	12	history	history	NOUN
fnp-3453	46	13	of	of	ADP
fnp-3453	46	14	repetitive	repetitive	ADJ
fnp-3453	46	15	head	head	NOUN
fnp-3453	46	16	trauma	trauma	NOUN
fnp-3453	46	17	or	or	CCONJ
fnp-3453	46	18	neurodegenerative	neurodegenerative	ADJ
fnp-3453	46	19	disease	disease	NOUN
fnp-3453	46	20	(	(	PUNCT
fnp-3453	46	21	control	control	NOUN
fnp-3453	46	22	)	)	PUNCT
fnp-3453	46	23	,	,	PUNCT
fnp-3453	46	24	5	5	NUM
fnp-3453	46	25	cases	case	NOUN
fnp-3453	46	26	with	with	ADP
fnp-3453	46	27	a	a	DET
fnp-3453	46	28	history	history	NOUN
fnp-3453	46	29	of	of	ADP
fnp-3453	46	30	repetitive	repetitive	ADJ
fnp-3453	46	31	head	head	NOUN
fnp-3453	46	32	trauma	trauma	NOUN
fnp-3453	46	33	but	but	CCONJ
fnp-3453	46	34	no	no	DET
fnp-3453	46	35	neurodegenerative	neurodegenerative	ADJ
fnp-3453	46	36	disease	disease	NOUN
fnp-3453	46	37	(	(	PUNCT
fnp-3453	46	38	rhi	rhi	NOUN
fnp-3453	46	39	)	)	PUNCT
fnp-3453	46	40	,	,	PUNCT
fnp-3453	46	41	and	and	CCONJ
fnp-3453	46	42	10	10	NUM
fnp-3453	46	43	cases	case	NOUN
fnp-3453	46	44	with	with	ADP
fnp-3453	46	45	a	a	DET
fnp-3453	46	46	history	history	NOUN
fnp-3453	46	47	of	of	ADP
fnp-3453	46	48	repetitive	repetitive	ADJ
fnp-3453	46	49	head	head	NOUN
fnp-3453	46	50	trauma	trauma	NOUN
fnp-3453	46	51	and	and	CCONJ
fnp-3453	46	52	a	a	DET
fnp-3453	46	53	diagnosis	diagnosis	NOUN
fnp-3453	46	54	of	of	ADP
fnp-3453	46	55	low	low	ADJ
fnp-3453	46	56	stage	stage	NOUN
fnp-3453	46	57	cte	cte	NOUN
fnp-3453	46	58	(	(	PUNCT
fnp-3453	46	59	cte	cte	PROPN
fnp-3453	46	60	)	)	PUNCT
fnp-3453	46	61	.	.	PUNCT
fnp-3453	47	1	there	there	PRON
fnp-3453	47	2	was	be	VERB
fnp-3453	47	3	no	no	DET
fnp-3453	47	4	difference	difference	NOUN
fnp-3453	47	5	in	in	ADP
fnp-3453	47	6	the	the	DET
fnp-3453	47	7	mean	mean	ADJ
fnp-3453	47	8	age	age	NOUN
fnp-3453	47	9	of	of	ADP
fnp-3453	47	10	death	death	NOUN
fnp-3453	47	11	of	of	ADP
fnp-3453	47	12	each	each	DET
fnp-3453	47	13	group	group	NOUN
fnp-3453	47	14	:	:	PUNCT
fnp-3453	47	15	control51.3	control51.3	VERB
fnp-3453	47	16	years	year	NOUN
fnp-3453	47	17	old	old	ADJ
fnp-3453	47	18	±	±	NUM
fnp-3453	47	19	8.2	8.2	NUM
fnp-3453	47	20	,	,	PUNCT
fnp-3453	47	21	rhi51.4	rhi51.4	PROPN
fnp-3453	47	22	years	year	NOUN
fnp-3453	47	23	old	old	ADJ
fnp-3453	47	24	±	±	NUM
fnp-3453	47	25	6.8	6.8	NUM
fnp-3453	47	26	,	,	PUNCT
fnp-3453	47	27	cte49.5	cte49.5	NOUN
fnp-3453	47	28	years	year	NOUN
fnp-3453	47	29	old	old	ADJ
fnp-3453	47	30	±	±	NUM
fnp-3453	47	31	8.1	8.1	NUM
fnp-3453	47	32	.	.	PUNCT
fnp-3453	48	1	all	all	DET
fnp-3453	48	2	cases	case	NOUN
fnp-3453	48	3	were	be	AUX
fnp-3453	48	4	male	male	ADJ
fnp-3453	48	5	and	and	CCONJ
fnp-3453	48	6	had	have	VERB
fnp-3453	48	7	a	a	DET
fnp-3453	48	8	history	history	NOUN
fnp-3453	48	9	of	of	ADP
fnp-3453	48	10	playing	play	VERB
fnp-3453	48	11	american	american	ADJ
fnp-3453	48	12	football	football	NOUN
fnp-3453	48	13	.	.	PUNCT
fnp-3453	49	1	individual	individual	ADJ
fnp-3453	49	2	descriptive	descriptive	ADJ
fnp-3453	49	3	statistics	statistic	NOUN
fnp-3453	49	4	for	for	ADP
fnp-3453	49	5	the	the	DET
fnp-3453	49	6	age	age	NOUN
fnp-3453	49	7	at	at	ADP
fnp-3453	49	8	death	death	NOUN
fnp-3453	49	9	,	,	PUNCT
fnp-3453	49	10	years	year	NOUN
fnp-3453	49	11	of	of	ADP
fnp-3453	49	12	exposure	exposure	NOUN
fnp-3453	49	13	,	,	PUNCT
fnp-3453	49	14	sport	sport	NOUN
fnp-3453	49	15	played	play	VERB
fnp-3453	49	16	,	,	PUNCT
fnp-3453	49	17	and	and	CCONJ
fnp-3453	49	18	rna	rna	NOUN
fnp-3453	49	19	integrity	integrity	NOUN
fnp-3453	49	20	number	number	NOUN
fnp-3453	49	21	(	(	PUNCT
fnp-3453	49	22	rin	rin	NOUN
fnp-3453	49	23	)	)	PUNCT
fnp-3453	49	24	,	,	PUNCT
fnp-3453	49	25	are	be	AUX
fnp-3453	49	26	provided	provide	VERB
fnp-3453	49	27	in	in	ADP
fnp-3453	49	28	table	table	NOUN
fnp-3453	49	29	1	1	NUM
fnp-3453	49	30	.	.	PUNCT
fnp-3453	50	1	next	next	ADJ
fnp-3453	50	2	-	-	PUNCT
fnp-3453	50	3	of	of	ADP
fnp-3453	50	4	-	-	PUNCT
fnp-3453	50	5	kin	kin	NOUN
fnp-3453	50	6	provided	provide	VERB
fnp-3453	50	7	written	write	VERB
fnp-3453	50	8	consent	consent	NOUN
fnp-3453	50	9	for	for	ADP
fnp-3453	50	10	participation	participation	NOUN
fnp-3453	50	11	and	and	CCONJ
fnp-3453	50	12	donation	donation	NOUN
fnp-3453	50	13	.	.	PUNCT
fnp-3453	51	1	institutional	institutional	ADJ
fnp-3453	51	2	review	review	PROPN
fnp-3453	51	3	board	board	NOUN
fnp-3453	51	4	approval	approval	NOUN
fnp-3453	51	5	for	for	ADP
fnp-3453	51	6	brain	brain	NOUN
fnp-3453	51	7	donation	donation	NOUN
fnp-3453	51	8	was	be	AUX
fnp-3453	51	9	obtained	obtain	VERB
fnp-3453	51	10	through	through	ADP
fnp-3453	51	11	the	the	DET
fnp-3453	51	12	boston	boston	PROPN
fnp-3453	51	13	university	university	PROPN
fnp-3453	51	14	alzheimer	alzheimer	PROPN
fnp-3453	51	15	’s	’s	PART
fnp-3453	51	16	disease	disease	NOUN
fnp-3453	51	17	and	and	CCONJ
fnp-3453	51	18	cte	cte	PROPN
fnp-3453	51	19	center	center	NOUN
fnp-3453	51	20	,	,	PUNCT
fnp-3453	51	21	human	human	ADJ
fnp-3453	51	22	subjects	subject	NOUN
fnp-3453	51	23	institutional	institutional	ADJ
fnp-3453	51	24	review	review	NOUN
fnp-3453	51	25	board	board	NOUN
fnp-3453	51	26	of	of	ADP
fnp-3453	51	27	the	the	DET
fnp-3453	51	28	boston	boston	PROPN
fnp-3453	51	29	university	university	PROPN
fnp-3453	51	30	school	school	NOUN
fnp-3453	51	31	of	of	ADP
fnp-3453	51	32	medicine	medicine	NOUN
fnp-3453	51	33	,	,	PUNCT
fnp-3453	51	34	and	and	CCONJ
fnp-3453	51	35	edith	edith	PROPN
fnp-3453	51	36	nourse	nourse	PROPN
fnp-3453	51	37	rogers	rogers	PROPN
fnp-3453	51	38	memorial	memorial	PROPN
fnp-3453	51	39	veterans	veterans	PROPN
fnp-3453	51	40	hospital	hospital	PROPN
fnp-3453	51	41	(	(	PUNCT
fnp-3453	51	42	bedford	bedford	PROPN
fnp-3453	51	43	,	,	PUNCT
fnp-3453	51	44	ma	ma	PROPN
fnp-3453	51	45	)	)	PUNCT
fnp-3453	51	46	.	.	PUNCT
fnp-3453	52	1	neuropathological	neuropathological	ADJ
fnp-3453	52	2	assessment	assessment	NOUN
fnp-3453	52	3	post	post	ADJ
fnp-3453	52	4	-	-	ADJ
fnp-3453	52	5	mortem	mortem	ADJ
fnp-3453	52	6	fresh	fresh	ADJ
fnp-3453	52	7	frozen	frozen	ADJ
fnp-3453	52	8	tissue	tissue	NOUN
fnp-3453	52	9	from	from	ADP
fnp-3453	52	10	the	the	DET
fnp-3453	52	11	dorsolateral	dorsolateral	ADJ
fnp-3453	52	12	frontal	frontal	ADJ
fnp-3453	52	13	cortex	cortex	NOUN
fnp-3453	52	14	was	be	AUX
fnp-3453	52	15	obtained	obtain	VERB
fnp-3453	52	16	using	use	VERB
fnp-3453	52	17	previously	previously	ADV
fnp-3453	52	18	described	describe	VERB
fnp-3453	52	19	procedures	procedure	NOUN
fnp-3453	52	20	[	[	X
fnp-3453	52	21	4	4	NUM
fnp-3453	52	22	]	]	PUNCT
fnp-3453	52	23	.	.	PUNCT
fnp-3453	53	1	neuropathologic	neuropathologic	ADJ
fnp-3453	53	2	diagnosis	diagnosis	NOUN
fnp-3453	53	3	was	be	AUX
fnp-3453	53	4	obtained	obtain	VERB
fnp-3453	53	5	from	from	ADP
fnp-3453	53	6	formalin	formalin	NOUN
fnp-3453	53	7	fixed	fix	VERB
fnp-3453	53	8	paraffin	paraffin	NOUN
fnp-3453	53	9	embedded	embed	VERB
fnp-3453	53	10	tissue	tissue	NOUN
fnp-3453	53	11	as	as	SCONJ
fnp-3453	53	12	previously	previously	ADV
fnp-3453	53	13	described	describe	VERB
fnp-3453	53	14	[	[	X
fnp-3453	53	15	21	21	NUM
fnp-3453	53	16	,	,	PUNCT
fnp-3453	53	17	24	24	NUM
fnp-3453	53	18	]	]	PUNCT
fnp-3453	53	19	.	.	PUNCT
fnp-3453	54	1	briefly	briefly	NOUN
fnp-3453	54	2	,	,	PUNCT
fnp-3453	54	3	22	22	NUM
fnp-3453	54	4	sections	section	NOUN
fnp-3453	54	5	of	of	ADP
fnp-3453	54	6	paraffin	paraffin	NOUN
fnp-3453	54	7	embedded	embed	VERB
fnp-3453	54	8	tissue	tissue	NOUN
fnp-3453	54	9	were	be	AUX
fnp-3453	54	10	stained	stain	VERB
fnp-3453	54	11	for	for	ADP
fnp-3453	54	12	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-3453	54	13	tau	tau	PROPN
fnp-3453	54	14	(	(	PUNCT
fnp-3453	54	15	p	p	PROPN
fnp-3453	54	16	-	-	PUNCT
fnp-3453	54	17	tau	tau	NOUN
fnp-3453	54	18	)	)	PUNCT
fnp-3453	54	19	,	,	PUNCT
fnp-3453	54	20	alpha	alpha	NOUN
fnp-3453	54	21	-	-	PUNCT
fnp-3453	54	22	synuclein	synuclein	NOUN
fnp-3453	54	23	,	,	PUNCT
fnp-3453	54	24	amyloid	amyloid	NOUN
fnp-3453	54	25	beta	beta	NOUN
fnp-3453	54	26	,	,	PUNCT
fnp-3453	54	27	tdp-43	tdp-43	PROPN
fnp-3453	54	28	,	,	PUNCT
fnp-3453	54	29	luxol	luxol	NOUN
fnp-3453	54	30	fast	fast	ADJ
fnp-3453	54	31	blue	blue	ADJ
fnp-3453	54	32	,	,	PUNCT
fnp-3453	54	33	and	and	CCONJ
fnp-3453	54	34	hematoxylin	hematoxylin	NOUN
fnp-3453	54	35	and	and	CCONJ
fnp-3453	54	36	eosin	eosin	NOUN
fnp-3453	54	37	using	use	VERB
fnp-3453	54	38	previously	previously	ADV
fnp-3453	54	39	described	describe	VERB
fnp-3453	54	40	methods	method	NOUN
fnp-3453	54	41	[	[	X
fnp-3453	54	42	22	22	NUM
fnp-3453	54	43	]	]	PUNCT
fnp-3453	54	44	.	.	PUNCT
fnp-3453	55	1	a	a	DET
fnp-3453	55	2	neuropathologic	neuropathologic	ADJ
fnp-3453	55	3	diagnosis	diagnosis	NOUN
fnp-3453	55	4	of	of	ADP
fnp-3453	55	5	cte	cte	NOUN
fnp-3453	55	6	was	be	AUX
fnp-3453	55	7	made	make	VERB
fnp-3453	55	8	using	use	VERB
fnp-3453	55	9	national	national	ADJ
fnp-3453	55	10	institute	institute	PROPN
fnp-3453	55	11	of	of	ADP
fnp-3453	55	12	neurological	neurological	ADJ
fnp-3453	55	13	disorders	disorder	NOUN
fnp-3453	55	14	and	and	CCONJ
fnp-3453	55	15	stroke	stroke	NOUN
fnp-3453	55	16	(	(	PUNCT
fnp-3453	55	17	ninds	nind	NOUN
fnp-3453	55	18	)	)	PUNCT
fnp-3453	55	19	consensus	consensus	NOUN
fnp-3453	55	20	criteria	criterion	NOUN
fnp-3453	55	21	[	[	X
fnp-3453	55	22	3	3	NUM
fnp-3453	55	23	,	,	PUNCT
fnp-3453	55	24	21	21	NUM
fnp-3453	55	25	]	]	PUNCT
fnp-3453	55	26	.	.	PUNCT
fnp-3453	56	1	cte	cte	PROPN
fnp-3453	56	2	cases	case	NOUN
fnp-3453	56	3	could	could	AUX
fnp-3453	56	4	be	be	AUX
fnp-3453	56	5	subdivided	subdivide	VERB
fnp-3453	56	6	based	base	VERB
fnp-3453	56	7	on	on	ADP
fnp-3453	56	8	the	the	DET
fnp-3453	56	9	presence	presence	NOUN
fnp-3453	56	10	,	,	PUNCT
fnp-3453	56	11	extent	extent	NOUN
fnp-3453	56	12	,	,	PUNCT
fnp-3453	56	13	and	and	CCONJ
fnp-3453	56	14	severity	severity	NOUN
fnp-3453	56	15	of	of	ADP
fnp-3453	56	16	p	p	PROPN
fnp-3453	56	17	-	-	PUNCT
fnp-3453	56	18	tau	tau	PROPN
fnp-3453	56	19	deposition	deposition	NOUN
fnp-3453	56	20	through	through	ADP
fnp-3453	56	21	the	the	DET
fnp-3453	56	22	brain	brain	NOUN
fnp-3453	56	23	.	.	PUNCT
fnp-3453	57	1	as	as	SCONJ
fnp-3453	57	2	the	the	DET
fnp-3453	57	3	focus	focus	NOUN
fnp-3453	57	4	of	of	ADP
fnp-3453	57	5	the	the	DET
fnp-3453	57	6	study	study	NOUN
fnp-3453	57	7	was	be	AUX
fnp-3453	57	8	to	to	PART
fnp-3453	57	9	examine	examine	VERB
fnp-3453	57	10	early	early	ADJ
fnp-3453	57	11	changes	change	NOUN
fnp-3453	57	12	,	,	PUNCT
fnp-3453	57	13	only	only	ADV
fnp-3453	57	14	cases	case	NOUN
fnp-3453	57	15	that	that	PRON
fnp-3453	57	16	met	meet	VERB
fnp-3453	57	17	the	the	DET
fnp-3453	57	18	“	"	PUNCT
fnp-3453	57	19	low	low	ADJ
fnp-3453	57	20	stage	stage	NOUN
fnp-3453	57	21	cte	cte	NOUN
fnp-3453	57	22	”	"	PUNCT
fnp-3453	57	23	criteria	criterion	NOUN
fnp-3453	57	24	were	be	AUX
fnp-3453	57	25	used	use	VERB
fnp-3453	57	26	for	for	ADP
fnp-3453	57	27	analysis	analysis	NOUN
fnp-3453	57	28	.	.	PUNCT
fnp-3453	58	1	the	the	DET
fnp-3453	58	2	low	low	ADJ
fnp-3453	58	3	stage	stage	NOUN
fnp-3453	58	4	cte	cte	NOUN
fnp-3453	58	5	designation	designation	NOUN
fnp-3453	58	6	encompasses	encompass	VERB
fnp-3453	58	7	cte	cte	NOUN
fnp-3453	58	8	stage	stage	NOUN
fnp-3453	58	9	i&ii	i&ii	NOUN
fnp-3453	58	10	[	[	X
fnp-3453	58	11	2	2	NUM
fnp-3453	58	12	,	,	PUNCT
fnp-3453	58	13	21	21	NUM
fnp-3453	58	14	]	]	PUNCT
fnp-3453	58	15	and	and	CCONJ
fnp-3453	58	16	shows	show	VERB
fnp-3453	58	17	strong	strong	ADJ
fnp-3453	58	18	agreement	agreement	NOUN
fnp-3453	58	19	with	with	ADP
fnp-3453	58	20	the	the	DET
fnp-3453	58	21	recent	recent	ADJ
fnp-3453	58	22	ninds	nind	NOUN
fnp-3453	58	23	consensus	consensus	NOUN
fnp-3453	58	24	staging	staging	NOUN
fnp-3453	58	25	for	for	ADP
fnp-3453	58	26	low	low	ADJ
fnp-3453	58	27	stage	stage	NOUN
fnp-3453	58	28	cte	cte	NOUN
fnp-3453	59	1	[	[	X
fnp-3453	59	2	3	3	NUM
fnp-3453	59	3	]	]	PUNCT
fnp-3453	59	4	.	.	PUNCT
fnp-3453	60	1	neuropathologic	neuropathologic	ADJ
fnp-3453	60	2	examination	examination	NOUN
fnp-3453	60	3	occurred	occurred	AUX
fnp-3453	60	4	blinded	blind	VERB
fnp-3453	60	5	to	to	ADP
fnp-3453	60	6	clinical	clinical	ADJ
fnp-3453	60	7	results	result	NOUN
fnp-3453	60	8	.	.	PUNCT
fnp-3453	61	1	all	all	DET
fnp-3453	61	2	evaluations	evaluation	NOUN
fnp-3453	61	3	were	be	AUX
fnp-3453	61	4	reviewed	review	VERB
fnp-3453	61	5	by	by	ADP
fnp-3453	61	6	four	four	NUM
fnp-3453	61	7	neuropathologists	neuropathologist	NOUN
fnp-3453	61	8	(	(	PUNCT
fnp-3453	61	9	va	va	NOUN
fnp-3453	61	10	,	,	PUNCT
fnp-3453	61	11	bh	bh	NOUN
fnp-3453	61	12	,	,	PUNCT
fnp-3453	61	13	ts	ts	NOUN
fnp-3453	61	14	,	,	PUNCT
fnp-3453	61	15	am	be	AUX
fnp-3453	61	16	)	)	PUNCT
fnp-3453	61	17	;	;	PUNCT
fnp-3453	61	18	discrepancies	discrepancy	NOUN
fnp-3453	61	19	in	in	ADP
fnp-3453	61	20	the	the	DET
fnp-3453	61	21	diagnosis	diagnosis	NOUN
fnp-3453	61	22	were	be	AUX
fnp-3453	61	23	resolved	resolve	VERB
fnp-3453	61	24	by	by	ADP
fnp-3453	61	25	consensus	consensus	NOUN
fnp-3453	61	26	conference	conference	NOUN
fnp-3453	61	27	.	.	PUNCT
fnp-3453	62	1	demographics	demographic	NOUN
fnp-3453	62	2	,	,	PUNCT
fnp-3453	62	3	athletic	athletic	ADJ
fnp-3453	62	4	history	history	NOUN
fnp-3453	62	5	(	(	PUNCT
fnp-3453	62	6	type	type	NOUN
fnp-3453	62	7	of	of	ADP
fnp-3453	62	8	sports	sport	NOUN
fnp-3453	62	9	played	play	VERB
fnp-3453	62	10	,	,	PUNCT
fnp-3453	62	11	level	level	NOUN
fnp-3453	62	12	,	,	PUNCT
fnp-3453	62	13	position	position	NOUN
fnp-3453	62	14	,	,	PUNCT
fnp-3453	62	15	age	age	NOUN
fnp-3453	62	16	of	of	ADP
fnp-3453	62	17	first	first	ADJ
fnp-3453	62	18	exposure	exposure	NOUN
fnp-3453	62	19	to	to	ADP
fnp-3453	62	20	sports	sport	NOUN
fnp-3453	62	21	and	and	CCONJ
fnp-3453	62	22	years	year	NOUN
fnp-3453	62	23	playing	play	VERB
fnp-3453	62	24	contact	contact	NOUN
fnp-3453	62	25	sports	sport	NOUN
fnp-3453	62	26	)	)	PUNCT
fnp-3453	62	27	,	,	PUNCT
fnp-3453	62	28	military	military	ADJ
fnp-3453	62	29	history	history	NOUN
fnp-3453	62	30	(	(	PUNCT
fnp-3453	62	31	branch	branch	NOUN
fnp-3453	62	32	,	,	PUNCT
fnp-3453	62	33	location	location	NOUN
fnp-3453	62	34	of	of	ADP
fnp-3453	62	35	service	service	NOUN
fnp-3453	62	36	and	and	CCONJ
fnp-3453	62	37	duration	duration	NOUN
fnp-3453	62	38	of	of	ADP
fnp-3453	62	39	combat	combat	NOUN
fnp-3453	62	40	exposure	exposure	NOUN
fnp-3453	62	41	)	)	PUNCT
fnp-3453	62	42	,	,	PUNCT
fnp-3453	62	43	and	and	CCONJ
fnp-3453	62	44	traumatic	traumatic	ADJ
fnp-3453	62	45	brain	brain	NOUN
fnp-3453	62	46	injury	injury	NOUN
fnp-3453	62	47	(	(	PUNCT
fnp-3453	62	48	tbi	tbi	NOUN
fnp-3453	62	49	)	)	PUNCT
fnp-3453	62	50	history	history	NOUN
fnp-3453	62	51	(	(	PUNCT
fnp-3453	62	52	including	include	VERB
fnp-3453	62	53	number	number	NOUN
fnp-3453	62	54	of	of	ADP
fnp-3453	62	55	concussions	concussion	NOUN
fnp-3453	62	56	)	)	PUNCT
fnp-3453	62	57	were	be	AUX
fnp-3453	62	58	queried	query	VERB
fnp-3453	62	59	during	during	ADP
fnp-3453	62	60	a	a	DET
fnp-3453	62	61	telephone	telephone	NOUN
fnp-3453	62	62	interview	interview	NOUN
fnp-3453	62	63	as	as	SCONJ
fnp-3453	62	64	detailed	detailed	ADJ
fnp-3453	62	65	previously	previously	ADV
fnp-3453	62	66	[	[	X
fnp-3453	62	67	30	30	NUM
fnp-3453	62	68	]	]	PUNCT
fnp-3453	62	69	.	.	PUNCT
fnp-3453	63	1	rna	rna	NOUN
fnp-3453	63	2	-	-	PUNCT
fnp-3453	63	3	sequencing	sequence	VERB
fnp-3453	63	4	50	50	NUM
fnp-3453	63	5	µg	µg	NOUN
fnp-3453	63	6	of	of	ADP
fnp-3453	63	7	fresh	fresh	ADJ
fnp-3453	63	8	frozen	frozen	ADJ
fnp-3453	63	9	tissue	tissue	NOUN
fnp-3453	63	10	was	be	AUX
fnp-3453	63	11	taken	take	VERB
fnp-3453	63	12	from	from	ADP
fnp-3453	63	13	the	the	DET
fnp-3453	63	14	dorsolateral	dorsolateral	ADJ
fnp-3453	63	15	frontal	frontal	ADJ
fnp-3453	63	16	cortex	cortex	NOUN
fnp-3453	63	17	grey	grey	NOUN
fnp-3453	63	18	matter	matter	NOUN
fnp-3453	63	19	at	at	ADP
fnp-3453	63	20	two	two	NUM
fnp-3453	63	21	locations	location	NOUN
fnp-3453	63	22	for	for	ADP
fnp-3453	63	23	each	each	DET
fnp-3453	63	24	case	case	NOUN
fnp-3453	63	25	:	:	PUNCT
fnp-3453	63	26	the	the	DET
fnp-3453	63	27	depth	depth	NOUN
fnp-3453	63	28	of	of	ADP
fnp-3453	63	29	the	the	DET
fnp-3453	63	30	superior	superior	ADJ
fnp-3453	63	31	frontal	frontal	ADJ
fnp-3453	63	32	cortical	cortical	ADJ
fnp-3453	63	33	sulcus	sulcus	NOUN
fnp-3453	63	34	(	(	PUNCT
fnp-3453	63	35	defined	define	VERB
fnp-3453	63	36	as	as	ADP
fnp-3453	63	37	the	the	DET
fnp-3453	63	38	bottom	bottom	ADJ
fnp-3453	63	39	third	third	NOUN
fnp-3453	63	40	of	of	ADP
fnp-3453	63	41	the	the	DET
fnp-3453	63	42	sulcus	sulcus	NOUN
fnp-3453	63	43	)	)	PUNCT
fnp-3453	63	44	and	and	CCONJ
fnp-3453	63	45	the	the	DET
fnp-3453	63	46	associated	associated	ADJ
fnp-3453	63	47	neighboring	neighboring	NOUN
fnp-3453	63	48	gryal	gryal	ADJ
fnp-3453	63	49	crest	crest	NOUN
fnp-3453	63	50	at	at	ADP
fnp-3453	63	51	the	the	DET
fnp-3453	63	52	level	level	NOUN
fnp-3453	63	53	of	of	ADP
fnp-3453	63	54	the	the	DET
fnp-3453	63	55	anterior	anterior	ADJ
fnp-3453	63	56	caudate	caudate	NOUN
fnp-3453	63	57	nucleus	nucleus	NOUN
fnp-3453	63	58	.	.	PUNCT
fnp-3453	64	1	frozen	frozen	ADJ
fnp-3453	64	2	tissue	tissue	NOUN
fnp-3453	64	3	was	be	AUX
fnp-3453	64	4	process	process	NOUN
fnp-3453	64	5	using	use	VERB
fnp-3453	64	6	a	a	DET
fnp-3453	64	7	mortar	mortar	NOUN
fnp-3453	64	8	and	and	CCONJ
fnp-3453	64	9	pestle	pestle	NOUN
fnp-3453	64	10	,	,	PUNCT
fnp-3453	64	11	and	and	CCONJ
fnp-3453	64	12	mrna	mrna	PROPN
fnp-3453	64	13	was	be	AUX
fnp-3453	64	14	extracted	extract	VERB
fnp-3453	64	15	and	and	CCONJ
fnp-3453	64	16	isolated	isolate	VERB
fnp-3453	64	17	using	use	VERB
fnp-3453	64	18	a	a	DET
fnp-3453	64	19	maxwell	maxwell	PROPN
fnp-3453	64	20	rna	rna	NOUN
fnp-3453	64	21	extraction	extraction	NOUN
fnp-3453	64	22	kit	kit	NOUN
fnp-3453	64	23	(	(	PUNCT
fnp-3453	64	24	promega	promega	NOUN
fnp-3453	64	25	)	)	PUNCT
fnp-3453	64	26	as	as	ADP
fnp-3453	64	27	per	per	ADP
fnp-3453	64	28	manufactures	manufacture	NOUN
fnp-3453	64	29	instruction	instruction	NOUN
fnp-3453	64	30	.	.	PUNCT
fnp-3453	65	1	an	an	DET
fnp-3453	65	2	ion	ion	NOUN
fnp-3453	65	3	apliseq	apliseq	VERB
fnp-3453	65	4	transcriptome	transcriptome	ADJ
fnp-3453	65	5	human	human	ADJ
fnp-3453	65	6	gene	gene	NOUN
fnp-3453	65	7	expression	expression	NOUN
fnp-3453	65	8	kit	kit	NOUN
fnp-3453	65	9	(	(	PUNCT
fnp-3453	65	10	thermofisher	thermofisher	PROPN
fnp-3453	65	11	scientific	scientific	NOUN
fnp-3453	65	12	)	)	PUNCT
fnp-3453	65	13	was	be	AUX
fnp-3453	65	14	then	then	ADV
fnp-3453	65	15	used	use	VERB
fnp-3453	65	16	to	to	PART
fnp-3453	65	17	convert	convert	VERB
fnp-3453	65	18	mrna	mrna	NOUN
fnp-3453	65	19	to	to	ADP
fnp-3453	65	20	cdna	cdna	PROPN
fnp-3453	65	21	and	and	CCONJ
fnp-3453	65	22	establish	establish	VERB
fnp-3453	65	23	human	human	ADJ
fnp-3453	65	24	transcriptome	transcriptome	PROPN
fnp-3453	65	25	cdna	cdna	PROPN
fnp-3453	65	26	libraries	library	NOUN
fnp-3453	65	27	as	as	ADP
fnp-3453	65	28	per	per	ADP
fnp-3453	65	29	manufactures	manufacture	NOUN
fnp-3453	65	30	instructions	instruction	NOUN
fnp-3453	65	31	.	.	PUNCT
fnp-3453	66	1	human	human	ADJ
fnp-3453	66	2	transcriptome	transcriptome	PROPN
fnp-3453	66	3	libraries	library	NOUN
fnp-3453	66	4	were	be	AUX
fnp-3453	66	5	then	then	ADV
fnp-3453	66	6	sequenced	sequence	VERB
fnp-3453	66	7	using	use	VERB
fnp-3453	66	8	an	an	DET
fnp-3453	66	9	ion	ion	NOUN
fnp-3453	66	10	torrent	torrent	NOUN
fnp-3453	66	11	s5	s5	PROPN
fnp-3453	66	12	next	next	ADJ
fnp-3453	66	13	generation	generation	NOUN
fnp-3453	66	14	sequencer	sequencer	NOUN
fnp-3453	66	15	(	(	PUNCT
fnp-3453	66	16	thermofisher	thermofisher	ADJ
fnp-3453	66	17	scientific	scientific	NOUN
fnp-3453	66	18	)	)	PUNCT
fnp-3453	66	19	.	.	PUNCT
fnp-3453	67	1	samples	sample	NOUN
fnp-3453	67	2	were	be	AUX
fnp-3453	67	3	processed	process	VERB
fnp-3453	67	4	and	and	CCONJ
fnp-3453	67	5	run	run	VERB
fnp-3453	67	6	across	across	ADP
fnp-3453	67	7	two	two	NUM
fnp-3453	67	8	batches	batch	NOUN
fnp-3453	67	9	.	.	PUNCT
fnp-3453	68	1	batch	batch	NOUN
fnp-3453	68	2	one	one	NUM
fnp-3453	68	3	contained	contain	VERB
fnp-3453	68	4	6	6	NUM
fnp-3453	68	5	control	control	NOUN
fnp-3453	68	6	and	and	CCONJ
fnp-3453	68	7	6	6	NUM
fnp-3453	68	8	cte	cte	NOUN
fnp-3453	68	9	cases	case	NOUN
fnp-3453	68	10	,	,	PUNCT
fnp-3453	68	11	and	and	CCONJ
fnp-3453	68	12	batch	batch	VERB
fnp-3453	68	13	two	two	NUM
fnp-3453	68	14	contained	contain	VERB
fnp-3453	68	15	5	5	NUM
fnp-3453	68	16	rhi	rhi	NOUN
fnp-3453	68	17	and	and	CCONJ
fnp-3453	68	18	4	4	NUM
fnp-3453	68	19	cte	cte	NOUN
fnp-3453	68	20	cases	case	NOUN
fnp-3453	68	21	and	and	CCONJ
fnp-3453	68	22	were	be	AUX
fnp-3453	68	23	compared	compare	VERB
fnp-3453	68	24	separately	separately	ADV
fnp-3453	68	25	to	to	PART
fnp-3453	68	26	avoid	avoid	VERB
fnp-3453	68	27	batch	batch	NOUN
fnp-3453	68	28	effects	effect	NOUN
fnp-3453	68	29	.	.	PUNCT
fnp-3453	69	1	normalized	normalize	VERB
fnp-3453	69	2	counts	count	NOUN
fnp-3453	69	3	for	for	ADP
fnp-3453	69	4	each	each	DET
fnp-3453	69	5	sample	sample	NOUN
fnp-3453	69	6	were	be	AUX
fnp-3453	69	7	determined	determine	VERB
fnp-3453	69	8	using	use	VERB
fnp-3453	69	9	the	the	DET
fnp-3453	69	10	ion	ion	NOUN
fnp-3453	69	11	torrent	torrent	NOUN
fnp-3453	69	12	suit	suit	NOUN
fnp-3453	69	13	software	software	VERB
fnp-3453	69	14	5.10	5.10	NUM
fnp-3453	69	15	and	and	CCONJ
fnp-3453	69	16	concatenated	concatenate	VERB
fnp-3453	69	17	together	together	ADV
fnp-3453	69	18	into	into	ADP
fnp-3453	69	19	genes	gene	NOUN
fnp-3453	69	20	by	by	ADP
fnp-3453	69	21	sample	sample	NOUN
fnp-3453	69	22	count	count	NOUN
fnp-3453	69	23	matrix	matrix	NOUN
fnp-3453	69	24	.	.	PUNCT
fnp-3453	70	1	the	the	DET
fnp-3453	70	2	normalized	normalize	VERB
fnp-3453	70	3	counts	count	NOUN
fnp-3453	70	4	were	be	AUX
fnp-3453	70	5	then	then	ADV
fnp-3453	70	6	transformed	transform	VERB
fnp-3453	70	7	with	with	ADP
fnp-3453	70	8	rlog	rlog	NOUN
fnp-3453	70	9	for	for	ADP
fnp-3453	70	10	principal	principal	ADJ
fnp-3453	70	11	component	component	NOUN
fnp-3453	70	12	analysis	analysis	NOUN
fnp-3453	70	13	(	(	PUNCT
fnp-3453	70	14	pca	pca	NOUN
fnp-3453	70	15	)	)	PUNCT
fnp-3453	70	16	.	.	PUNCT
fnp-3453	71	1	differential	differential	ADJ
fnp-3453	71	2	expression	expression	NOUN
fnp-3453	71	3	analysis	analysis	NOUN
fnp-3453	71	4	genes	gene	NOUN
fnp-3453	71	5	with	with	ADP
fnp-3453	71	6	more	more	ADJ
fnp-3453	71	7	than	than	ADP
fnp-3453	71	8	50	50	NUM
fnp-3453	71	9	%	%	NOUN
fnp-3453	71	10	zero	zero	NUM
fnp-3453	71	11	counts	count	NOUN
fnp-3453	71	12	within	within	ADP
fnp-3453	71	13	each	each	DET
fnp-3453	71	14	group	group	NOUN
fnp-3453	71	15	were	be	AUX
fnp-3453	71	16	filtered	filter	VERB
fnp-3453	71	17	out	out	ADP
fnp-3453	71	18	.	.	PUNCT
fnp-3453	72	1	pairwise	pairwise	NOUN
fnp-3453	72	2	differential	differential	NOUN
fnp-3453	72	3	expression	expression	NOUN
fnp-3453	72	4	(	(	PUNCT
fnp-3453	72	5	de	de	X
fnp-3453	72	6	)	)	PUNCT
fnp-3453	72	7	analyses	analysis	NOUN
fnp-3453	72	8	were	be	AUX
fnp-3453	72	9	conducted	conduct	VERB
fnp-3453	72	10	separately	separately	ADV
fnp-3453	72	11	for	for	ADP
fnp-3453	72	12	cte	cte	PROPN
fnp-3453	72	13	vs	vs	ADP
fnp-3453	72	14	rhi	rhi	PROPN
fnp-3453	72	15	and	and	CCONJ
fnp-3453	72	16	cte	cte	PROPN
fnp-3453	72	17	vs	vs	ADP
fnp-3453	72	18	control	control	NOUN
fnp-3453	72	19	using	use	VERB
fnp-3453	72	20	deseq2	deseq2	PROPN
fnp-3453	72	21	bioconductor	bioconductor	PROPN
fnp-3453	72	22	package	package	NOUN
fnp-3453	72	23	,	,	PUNCT
fnp-3453	72	24	modeling	model	VERB
fnp-3453	72	25	counts	count	NOUN
fnp-3453	72	26	as	as	ADP
fnp-3453	72	27	a	a	DET
fnp-3453	72	28	function	function	NOUN
fnp-3453	72	29	of	of	ADP
fnp-3453	72	30	case	case	NOUN
fnp-3453	72	31	status	status	NOUN
fnp-3453	72	32	adjusting	adjust	VERB
fnp-3453	72	33	for	for	ADP
fnp-3453	72	34	age	age	NOUN
fnp-3453	72	35	at	at	ADP
fnp-3453	72	36	death	death	NOUN
fnp-3453	72	37	[	[	X
fnp-3453	72	38	18	18	NUM
fnp-3453	72	39	]	]	PUNCT
fnp-3453	72	40	.	.	PUNCT
fnp-3453	73	1	to	to	PART
fnp-3453	73	2	analyze	analyze	VERB
fnp-3453	73	3	changes	change	NOUN
fnp-3453	73	4	between	between	ADP
fnp-3453	73	5	the	the	DET
fnp-3453	73	6	sulcus	sulcus	NOUN
fnp-3453	73	7	and	and	CCONJ
fnp-3453	73	8	crest	crest	NOUN
fnp-3453	73	9	within	within	ADP
fnp-3453	73	10	each	each	DET
fnp-3453	73	11	group	group	NOUN
fnp-3453	73	12	,	,	PUNCT
fnp-3453	73	13	a	a	DET
fnp-3453	73	14	ratio	ratio	NOUN
fnp-3453	73	15	between	between	ADP
fnp-3453	73	16	the	the	DET
fnp-3453	73	17	sulcus	sulcus	NOUN
fnp-3453	73	18	and	and	CCONJ
fnp-3453	73	19	crest	crest	NOUN
fnp-3453	73	20	genes	gene	NOUN
fnp-3453	73	21	were	be	AUX
fnp-3453	73	22	calculated	calculate	VERB
fnp-3453	73	23	using	use	VERB
fnp-3453	73	24	the	the	DET
fnp-3453	73	25	concatenated	concatenate	VERB
fnp-3453	73	26	normalized	normalize	VERB
fnp-3453	73	27	counts	count	NOUN
fnp-3453	73	28	matrix	matrix	NOUN
fnp-3453	73	29	.	.	PUNCT
fnp-3453	74	1	genes	gene	NOUN
fnp-3453	74	2	that	that	PRON
fnp-3453	74	3	could	could	AUX
fnp-3453	74	4	not	not	PART
fnp-3453	74	5	be	be	AUX
fnp-3453	74	6	detected	detect	VERB
fnp-3453	74	7	in	in	ADP
fnp-3453	74	8	all	all	DET
fnp-3453	74	9	samples	sample	NOUN
fnp-3453	74	10	(	(	PUNCT
fnp-3453	74	11	genes	gene	NOUN
fnp-3453	74	12	with	with	ADP
fnp-3453	74	13	0	0	NUM
fnp-3453	74	14	counts	count	NOUN
fnp-3453	74	15	for	for	ADP
fnp-3453	74	16	all	all	DET
fnp-3453	74	17	samples	sample	NOUN
fnp-3453	74	18	)	)	PUNCT
fnp-3453	74	19	were	be	AUX
fnp-3453	74	20	filtered	filter	VERB
fnp-3453	74	21	out	out	ADP
fnp-3453	74	22	.	.	PUNCT
fnp-3453	75	1	a	a	DET
fnp-3453	75	2	pseudocount	pseudocount	NOUN
fnp-3453	75	3	of	of	ADP
fnp-3453	75	4	0.01	0.01	NUM
fnp-3453	75	5	was	be	AUX
fnp-3453	75	6	added	add	VERB
fnp-3453	75	7	to	to	ADP
fnp-3453	75	8	the	the	DET
fnp-3453	75	9	counts	count	NOUN
fnp-3453	75	10	to	to	PART
fnp-3453	75	11	prevent	prevent	VERB
fnp-3453	75	12	infinity	infinity	NOUN
fnp-3453	75	13	values	value	NOUN
fnp-3453	75	14	from	from	ADP
fnp-3453	75	15	zero	zero	NUM
fnp-3453	75	16	divisions	division	NOUN
fnp-3453	75	17	.	.	PUNCT
fnp-3453	76	1	the	the	DET
fnp-3453	76	2	ratio	ratio	NOUN
fnp-3453	76	3	was	be	AUX
fnp-3453	76	4	then	then	ADV
fnp-3453	76	5	calculated	calculate	VERB
fnp-3453	76	6	as	as	ADP
fnp-3453	76	7	log	log	NOUN
fnp-3453	76	8	2	2	NUM
fnp-3453	76	9	of	of	ADP
fnp-3453	76	10	sulcus	sulcus	NOUN
fnp-3453	76	11	counts	count	NOUN
fnp-3453	76	12	divided	divide	VERB
fnp-3453	76	13	by	by	ADP
fnp-3453	76	14	crest	crest	NOUN
fnp-3453	76	15	counts	count	NOUN
fnp-3453	76	16	for	for	ADP
fnp-3453	76	17	each	each	DET
fnp-3453	76	18	gene	gene	NOUN
fnp-3453	76	19	within	within	ADP
fnp-3453	76	20	each	each	DET
fnp-3453	76	21	sample	sample	NOUN
fnp-3453	76	22	.	.	PUNCT
fnp-3453	77	1	to	to	PART
fnp-3453	77	2	attenuate	attenuate	VERB
fnp-3453	77	3	extreme	extreme	ADJ
fnp-3453	77	4	ratios	ratio	NOUN
fnp-3453	77	5	due	due	ADJ
fnp-3453	77	6	to	to	ADP
fnp-3453	77	7	small	small	ADJ
fnp-3453	77	8	count	count	NOUN
fnp-3453	77	9	values	value	NOUN
fnp-3453	77	10	in	in	ADP
fnp-3453	77	11	either	either	DET
fnp-3453	77	12	tissue	tissue	NOUN
fnp-3453	77	13	,	,	PUNCT
fnp-3453	77	14	the	the	DET
fnp-3453	77	15	ratios	ratio	NOUN
fnp-3453	77	16	were	be	AUX
fnp-3453	77	17	arcsin	arcsin	PROPN
fnp-3453	77	18	transformed	transform	VERB
fnp-3453	77	19	by	by	ADP
fnp-3453	77	20	first	first	ADJ
fnp-3453	77	21	dividing	dividing	NOUN
fnp-3453	77	22	by	by	ADP
fnp-3453	77	23	0.5	0.5	NUM
fnp-3453	77	24	and	and	CCONJ
fnp-3453	77	25	then	then	ADV
fnp-3453	77	26	applying	apply	VERB
fnp-3453	77	27	the	the	DET
fnp-3453	77	28	arcsin	arcsin	PROPN
fnp-3453	77	29	function	function	NOUN
fnp-3453	77	30	using	use	VERB
fnp-3453	77	31	the	the	DET
fnp-3453	77	32	numpy	numpy	NOUN
fnp-3453	77	33	python	python	NOUN
fnp-3453	77	34	package	package	NOUN
fnp-3453	77	35	.	.	PUNCT
fnp-3453	78	1	this	this	DET
fnp-3453	78	2	procedure	procedure	NOUN
fnp-3453	78	3	results	result	VERB
fnp-3453	78	4	in	in	ADP
fnp-3453	78	5	a	a	DET
fnp-3453	78	6	log2	log2	PROPN
fnp-3453	78	7	fold	fold	NOUN
fnp-3453	78	8	change	change	NOUN
fnp-3453	78	9	of	of	ADP
fnp-3453	78	10	sulcus	sulcus	NOUN
fnp-3453	78	11	vs	vs	ADP
fnp-3453	78	12	crest	crest	NOUN
fnp-3453	78	13	for	for	ADP
fnp-3453	78	14	each	each	DET
fnp-3453	78	15	gene	gene	NOUN
fnp-3453	78	16	in	in	ADP
fnp-3453	78	17	each	each	DET
fnp-3453	78	18	sample	sample	NOUN
fnp-3453	78	19	.	.	PUNCT
fnp-3453	79	1	to	to	PART
fnp-3453	79	2	identify	identify	VERB
fnp-3453	79	3	genes	gene	NOUN
fnp-3453	79	4	that	that	PRON
fnp-3453	79	5	exhibited	exhibit	VERB
fnp-3453	79	6	significantly	significantly	ADV
fnp-3453	79	7	different	different	ADJ
fnp-3453	79	8	expression	expression	NOUN
fnp-3453	79	9	between	between	ADP
fnp-3453	79	10	tissues	tissue	NOUN
fnp-3453	79	11	within	within	ADP
fnp-3453	79	12	each	each	DET
fnp-3453	79	13	case	case	NOUN
fnp-3453	79	14	status	status	NOUN
fnp-3453	79	15	,	,	PUNCT
fnp-3453	79	16	one	one	NUM
fnp-3453	79	17	-	-	PUNCT
fnp-3453	79	18	sample	sample	NOUN
fnp-3453	79	19	,	,	PUNCT
fnp-3453	79	20	two	two	NUM
fnp-3453	79	21	-	-	PUNCT
fnp-3453	79	22	tailed	tail	VERB
fnp-3453	79	23	t	t	NOUN
fnp-3453	79	24	-	-	PUNCT
fnp-3453	79	25	tests	test	NOUN
fnp-3453	79	26	comparing	compare	VERB
fnp-3453	79	27	with	with	ADP
fnp-3453	79	28	an	an	DET
fnp-3453	79	29	expected	expect	VERB
fnp-3453	79	30	mean	mean	ADJ
fnp-3453	79	31	log2	log2	PROPN
fnp-3453	79	32	fold	fold	NOUN
fnp-3453	79	33	change	change	NOUN
fnp-3453	79	34	of	of	ADP
fnp-3453	79	35	zero	zero	NUM
fnp-3453	79	36	were	be	AUX
fnp-3453	79	37	performed	perform	VERB
fnp-3453	79	38	for	for	ADP
fnp-3453	79	39	the	the	DET
fnp-3453	79	40	fold	fold	ADJ
fnp-3453	79	41	changes	change	NOUN
fnp-3453	79	42	of	of	ADP
fnp-3453	79	43	each	each	DET
fnp-3453	79	44	gene	gene	NOUN
fnp-3453	79	45	.	.	PUNCT
fnp-3453	80	1	p	p	X
fnp-3453	80	2	-	-	PUNCT
fnp-3453	80	3	values	value	NOUN
fnp-3453	80	4	were	be	AUX
fnp-3453	80	5	adjusted	adjust	VERB
fnp-3453	80	6	for	for	ADP
fnp-3453	80	7	multiple	multiple	ADJ
fnp-3453	80	8	hypotheses	hypothesis	NOUN
fnp-3453	80	9	using	use	VERB
fnp-3453	80	10	the	the	DET
fnp-3453	80	11	benjamini	benjamini	ADJ
fnp-3453	80	12	-	-	PUNCT
fnp-3453	80	13	hochberg	hochberg	NOUN
fnp-3453	80	14	procedure	procedure	NOUN
fnp-3453	80	15	.	.	PUNCT
fnp-3453	81	1	similarly	similarly	ADV
fnp-3453	81	2	,	,	PUNCT
fnp-3453	81	3	two	two	NUM
fnp-3453	81	4	-	-	PUNCT
fnp-3453	81	5	sample	sample	NOUN
fnp-3453	81	6	t	t	NOUN
fnp-3453	81	7	-	-	PUNCT
fnp-3453	81	8	tests	test	NOUN
fnp-3453	81	9	were	be	AUX
fnp-3453	81	10	run	run	VERB
fnp-3453	81	11	to	to	PART
fnp-3453	81	12	compare	compare	VERB
fnp-3453	81	13	the	the	DET
fnp-3453	81	14	sulcus	sulcus	NOUN
fnp-3453	81	15	vs	vs	ADP
fnp-3453	81	16	crest	crest	NOUN
fnp-3453	81	17	fold	fold	NOUN
fnp-3453	81	18	changes	change	NOUN
fnp-3453	81	19	for	for	ADP
fnp-3453	81	20	cte	cte	PROPN
fnp-3453	81	21	vs	vs	ADP
fnp-3453	81	22	rhi	rhi	PROPN
fnp-3453	81	23	,	,	PUNCT
fnp-3453	81	24	cte	cte	PROPN
fnp-3453	81	25	vs	vs	ADP
fnp-3453	81	26	control	control	NOUN
fnp-3453	81	27	,	,	PUNCT
fnp-3453	81	28	and	and	CCONJ
fnp-3453	81	29	rhi	rhi	PROPN
fnp-3453	81	30	vs	vs	ADP
fnp-3453	81	31	control	control	PROPN
fnp-3453	81	32	.	.	PUNCT
fnp-3453	82	1	gene	gene	NOUN
fnp-3453	82	2	set	set	VERB
fnp-3453	82	3	enrichment	enrichment	NOUN
fnp-3453	82	4	analysis	analysis	NOUN
fnp-3453	82	5	(	(	PUNCT
fnp-3453	82	6	gsea	gsea	NOUN
fnp-3453	82	7	)	)	PUNCT
fnp-3453	82	8	gene	gene	NOUN
fnp-3453	82	9	set	set	VERB
fnp-3453	82	10	enrichment	enrichment	NOUN
fnp-3453	82	11	analysis	analysis	NOUN
fnp-3453	82	12	for	for	ADP
fnp-3453	82	13	all	all	DET
fnp-3453	82	14	de	de	X
fnp-3453	82	15	gene	gene	NOUN
fnp-3453	82	16	lists	list	NOUN
fnp-3453	82	17	were	be	AUX
fnp-3453	82	18	performed	perform	VERB
fnp-3453	82	19	using	use	VERB
fnp-3453	82	20	the	the	DET
fnp-3453	82	21	fgsea	fgsea	NOUN
fnp-3453	82	22	r	r	NOUN
fnp-3453	82	23	package	package	NOUN
fnp-3453	82	24	in	in	ADP
fnp-3453	82	25	bioconductor	bioconductor	NOUN
fnp-3453	82	26	and	and	CCONJ
fnp-3453	82	27	gene	gene	NOUN
fnp-3453	82	28	ontology	ontology	NOUN
fnp-3453	82	29	(	(	PUNCT
fnp-3453	82	30	go	go	VERB
fnp-3453	82	31	)	)	PUNCT
fnp-3453	82	32	geneset	geneset	NOUN
fnp-3453	82	33	annotations	annotation	NOUN
fnp-3453	82	34	from	from	ADP
fnp-3453	82	35	goatools	goatools	PROPN
fnp-3453	82	36	python	python	PROPN
fnp-3453	82	37	package	package	NOUN
fnp-3453	82	38	[	[	X
fnp-3453	82	39	14	14	NUM
fnp-3453	82	40	,	,	PUNCT
fnp-3453	82	41	29	29	NUM
fnp-3453	82	42	]	]	PUNCT
fnp-3453	82	43	.	.	PUNCT
fnp-3453	83	1	gsea	gsea	NOUN
fnp-3453	83	2	statistics	statistic	NOUN
fnp-3453	83	3	were	be	AUX
fnp-3453	83	4	calculated	calculate	VERB
fnp-3453	83	5	using	use	VERB
fnp-3453	83	6	gene	gene	NOUN
fnp-3453	83	7	list	list	NOUN
fnp-3453	83	8	sorted	sort	VERB
fnp-3453	83	9	by	by	ADP
fnp-3453	83	10	descending	descend	VERB
fnp-3453	83	11	log2	log2	PROPN
fnp-3453	83	12	fold	fold	NOUN
fnp-3453	83	13	change	change	NOUN
fnp-3453	83	14	(	(	PUNCT
fnp-3453	83	15	from	from	ADP
fnp-3453	83	16	de	de	ADJ
fnp-3453	83	17	)	)	PUNCT
fnp-3453	83	18	or	or	CCONJ
fnp-3453	83	19	log	log	VERB
fnp-3453	83	20	2	2	NUM
fnp-3453	83	21	ratio	ratio	NOUN
fnp-3453	83	22	t	t	PROPN
fnp-3453	83	23	-	-	PUNCT
fnp-3453	83	24	statistics	statistic	NOUN
fnp-3453	83	25	,	,	PUNCT
fnp-3453	83	26	and	and	CCONJ
fnp-3453	83	27	significance	significance	NOUN
fnp-3453	83	28	was	be	AUX
fnp-3453	83	29	assessed	assess	VERB
fnp-3453	83	30	for	for	ADP
fnp-3453	83	31	gene	gene	NOUN
fnp-3453	83	32	sets	set	NOUN
fnp-3453	83	33	at	at	ADP
fnp-3453	83	34	fdr	fdr	PROPN
fnp-3453	83	35	<	<	X
fnp-3453	83	36	0.1	0.1	NUM
fnp-3453	83	37	.	.	PUNCT
fnp-3453	84	1	the	the	DET
fnp-3453	84	2	resulting	result	VERB
fnp-3453	84	3	normalized	normalize	VERB
fnp-3453	84	4	enrichment	enrichment	NOUN
fnp-3453	84	5	scores	score	NOUN
fnp-3453	84	6	(	(	PUNCT
fnp-3453	84	7	nes	ne	NOUN
fnp-3453	84	8	)	)	PUNCT
fnp-3453	84	9	were	be	AUX
fnp-3453	84	10	then	then	ADV
fnp-3453	84	11	used	use	VERB
fnp-3453	84	12	to	to	PART
fnp-3453	84	13	create	create	VERB
fnp-3453	84	14	heatmaps	heatmap	NOUN
fnp-3453	84	15	.	.	PUNCT
fnp-3453	85	1	gsea	gsea	ADJ
fnp-3453	85	2	biological	biological	ADJ
fnp-3453	85	3	process	process	NOUN
fnp-3453	85	4	were	be	AUX
fnp-3453	85	5	grouped	group	VERB
fnp-3453	85	6	into	into	ADP
fnp-3453	85	7	1	1	NUM
fnp-3453	85	8	out	out	ADP
fnp-3453	85	9	of	of	ADP
fnp-3453	85	10	11	11	NUM
fnp-3453	85	11	biological	biological	ADJ
fnp-3453	85	12	categories	category	NOUN
fnp-3453	85	13	by	by	ADP
fnp-3453	85	14	hand	hand	NOUN
fnp-3453	85	15	,	,	PUNCT
fnp-3453	85	16	based	base	VERB
fnp-3453	85	17	on	on	ADP
fnp-3453	85	18	expert	expert	ADJ
fnp-3453	85	19	opinion	opinion	NOUN
fnp-3453	85	20	.	.	PUNCT
fnp-3453	86	1	categories	category	NOUN
fnp-3453	86	2	were	be	AUX
fnp-3453	86	3	discussed	discuss	VERB
fnp-3453	86	4	and	and	CCONJ
fnp-3453	86	5	confirmed	confirm	VERB
fnp-3453	86	6	among	among	ADP
fnp-3453	86	7	3	3	NUM
fnp-3453	86	8	authors	author	NOUN
fnp-3453	86	9	(	(	PUNCT
fnp-3453	86	10	jc	jc	PROPN
fnp-3453	86	11	,	,	PUNCT
fnp-3453	86	12	al	al	PROPN
fnp-3453	86	13	,	,	PUNCT
fnp-3453	86	14	ts	ts	PROPN
fnp-3453	86	15	)	)	PUNCT
fnp-3453	86	16	.	.	PUNCT
fnp-3453	87	1	any	any	DET
fnp-3453	87	2	differences	difference	NOUN
fnp-3453	87	3	were	be	AUX
fnp-3453	87	4	resolved	resolve	VERB
fnp-3453	87	5	through	through	ADP
fnp-3453	87	6	consensus	consensus	NOUN
fnp-3453	87	7	conference	conference	NOUN
fnp-3453	87	8	.	.	PUNCT
fnp-3453	88	1	the	the	DET
fnp-3453	88	2	biological	biological	ADJ
fnp-3453	88	3	categories	category	NOUN
fnp-3453	88	4	were	be	AUX
fnp-3453	88	5	:	:	PUNCT
fnp-3453	88	6	immune	immune	ADJ
fnp-3453	88	7	,	,	PUNCT
fnp-3453	88	8	vascular	vascular	ADJ
fnp-3453	88	9	,	,	PUNCT
fnp-3453	88	10	neuronal	neuronal	ADJ
fnp-3453	88	11	,	,	PUNCT
fnp-3453	88	12	extracellular	extracellular	ADJ
fnp-3453	88	13	matrix	matrix	NOUN
fnp-3453	88	14	(	(	PUNCT
fnp-3453	88	15	ecm	ecm	PROPN
fnp-3453	88	16	)	)	PUNCT
fnp-3453	88	17	,	,	PUNCT
fnp-3453	88	18	mitochondrial	mitochondrial	ADJ
fnp-3453	88	19	/	/	SYM
fnp-3453	88	20	metabolism	metabolism	NOUN
fnp-3453	88	21	,	,	PUNCT
fnp-3453	88	22	signaling	signal	VERB
fnp-3453	88	23	,	,	PUNCT
fnp-3453	88	24	cytoskeleton	cytoskeleton	NOUN
fnp-3453	88	25	,	,	PUNCT
fnp-3453	88	26	transcription	transcription	NOUN
fnp-3453	88	27	/	/	SYM
fnp-3453	88	28	translation	translation	NOUN
fnp-3453	88	29	,	,	PUNCT
fnp-3453	88	30	endocytosis	endocytosis	NOUN
fnp-3453	88	31	/	/	SYM
fnp-3453	88	32	exocytosis	exocytosis	NOUN
fnp-3453	88	33	,	,	PUNCT
fnp-3453	88	34	protein	protein	NOUN
fnp-3453	88	35	processing	processing	NOUN
fnp-3453	88	36	,	,	PUNCT
fnp-3453	88	37	and	and	CCONJ
fnp-3453	88	38	any	any	DET
fnp-3453	88	39	process	process	NOUN
fnp-3453	88	40	that	that	PRON
fnp-3453	88	41	did	do	VERB
fnp-3453	88	42	n’t	not	PART
fnp-3453	88	43	fit	fit	VERB
fnp-3453	88	44	the	the	DET
fnp-3453	88	45	previous	previous	ADJ
fnp-3453	88	46	10	10	NUM
fnp-3453	88	47	category	category	NOUN
fnp-3453	88	48	was	be	AUX
fnp-3453	88	49	assigned	assign	VERB
fnp-3453	88	50	to	to	ADP
fnp-3453	88	51	“	"	PUNCT
fnp-3453	88	52	other	other	ADJ
fnp-3453	88	53	”	"	PUNCT
fnp-3453	88	54	.	.	PUNCT
fnp-3453	89	1	finally	finally	ADV
fnp-3453	89	2	,	,	PUNCT
fnp-3453	89	3	gene	gene	NOUN
fnp-3453	89	4	ontology	ontology	NOUN
fnp-3453	89	5	analysis	analysis	NOUN
fnp-3453	89	6	from	from	ADP
fnp-3453	89	7	common	common	ADJ
fnp-3453	89	8	or	or	CCONJ
fnp-3453	89	9	unique	unique	ADJ
fnp-3453	89	10	genes	gene	NOUN
fnp-3453	89	11	groups	group	NOUN
fnp-3453	89	12	was	be	AUX
fnp-3453	89	13	carried	carry	VERB
fnp-3453	89	14	out	out	ADP
fnp-3453	89	15	using	use	VERB
fnp-3453	89	16	metascape	metascape	NOUN
fnp-3453	89	17	[	[	X
fnp-3453	89	18	33	33	NUM
fnp-3453	89	19	]	]	PUNCT
fnp-3453	89	20	.	.	PUNCT
fnp-3453	90	1	all	all	DET
fnp-3453	90	2	code	code	NOUN
fnp-3453	90	3	and	and	CCONJ
fnp-3453	90	4	supplementary	supplementary	ADJ
fnp-3453	90	5	information	information	NOUN
fnp-3453	90	6	needed	need	VERB
fnp-3453	90	7	to	to	PART
fnp-3453	90	8	reproduce	reproduce	VERB
fnp-3453	90	9	this	this	DET
fnp-3453	90	10	analysis	analysis	NOUN
fnp-3453	90	11	is	be	AUX
fnp-3453	90	12	available	available	ADJ
fnp-3453	90	13	at	at	ADP
fnp-3453	90	14	https://osf.io/exsfa/.	https://osf.io/exsfa/.	PROPN
fnp-3453	90	15	results	result	NOUN
fnp-3453	90	16	overall	overall	ADV
fnp-3453	90	17	,	,	PUNCT
fnp-3453	90	18	3	3	NUM
fnp-3453	90	19	differential	differential	NOUN
fnp-3453	90	20	expression	expression	NOUN
fnp-3453	90	21	analyses	analysis	NOUN
fnp-3453	90	22	were	be	AUX
fnp-3453	90	23	carried	carry	VERB
fnp-3453	90	24	out	out	ADP
fnp-3453	90	25	.	.	PUNCT
fnp-3453	91	1	a	a	DET
fnp-3453	91	2	summary	summary	NOUN
fnp-3453	91	3	of	of	ADP
fnp-3453	91	4	each	each	DET
fnp-3453	91	5	comparison	comparison	NOUN
fnp-3453	91	6	is	be	AUX
fnp-3453	91	7	outlined	outline	VERB
fnp-3453	91	8	in	in	ADP
fnp-3453	91	9	figure	figure	NOUN
fnp-3453	91	10	1	1	NUM
fnp-3453	91	11	.	.	PUNCT
fnp-3453	92	1	the	the	DET
fnp-3453	92	2	first	first	ADJ
fnp-3453	92	3	analysis	analysis	NOUN
fnp-3453	92	4	was	be	AUX
fnp-3453	92	5	to	to	PART
fnp-3453	92	6	directly	directly	ADV
fnp-3453	92	7	compare	compare	VERB
fnp-3453	92	8	the	the	DET
fnp-3453	92	9	differentially	differentially	ADV
fnp-3453	92	10	expressed	express	VERB
fnp-3453	92	11	genes	gene	NOUN
fnp-3453	92	12	in	in	ADP
fnp-3453	92	13	the	the	DET
fnp-3453	92	14	sulcus	sulcus	NOUN
fnp-3453	92	15	or	or	CCONJ
fnp-3453	92	16	crest	crest	NOUN
fnp-3453	92	17	to	to	ADP
fnp-3453	92	18	the	the	DET
fnp-3453	92	19	matching	matching	NOUN
fnp-3453	92	20	region	region	NOUN
fnp-3453	92	21	across	across	ADP
fnp-3453	92	22	control	control	NOUN
fnp-3453	92	23	,	,	PUNCT
fnp-3453	92	24	rhi	rhi	PROPN
fnp-3453	92	25	,	,	PUNCT
fnp-3453	92	26	or	or	CCONJ
fnp-3453	92	27	cte	cte	NOUN
fnp-3453	92	28	groups	group	NOUN
fnp-3453	92	29	(	(	PUNCT
fnp-3453	92	30	figure	figure	VERB
fnp-3453	92	31	1a	1a	NOUN
fnp-3453	92	32	,	,	PUNCT
fnp-3453	92	33	comparison	comparison	NOUN
fnp-3453	92	34	1	1	NUM
fnp-3453	92	35	)	)	PUNCT
fnp-3453	92	36	.	.	PUNCT
fnp-3453	93	1	the	the	DET
fnp-3453	93	2	second	second	ADJ
fnp-3453	93	3	analysis	analysis	NOUN
fnp-3453	93	4	was	be	AUX
fnp-3453	93	5	to	to	PART
fnp-3453	93	6	directly	directly	ADV
fnp-3453	93	7	compare	compare	VERB
fnp-3453	93	8	the	the	DET
fnp-3453	93	9	sulcus	sulcus	NOUN
fnp-3453	93	10	vs.	vs.	ADP
fnp-3453	93	11	crest	crest	NOUN
fnp-3453	93	12	within	within	ADP
fnp-3453	93	13	each	each	DET
fnp-3453	93	14	group	group	NOUN
fnp-3453	93	15	(	(	PUNCT
fnp-3453	93	16	figure	figure	NOUN
fnp-3453	93	17	1b	1b	NUM
fnp-3453	93	18	,	,	PUNCT
fnp-3453	93	19	comparison	comparison	NOUN
fnp-3453	93	20	2	2	NUM
fnp-3453	93	21	)	)	PUNCT
fnp-3453	93	22	.	.	PUNCT
fnp-3453	94	1	the	the	DET
fnp-3453	94	2	final	final	ADJ
fnp-3453	94	3	analysis	analysis	NOUN
fnp-3453	94	4	was	be	AUX
fnp-3453	94	5	to	to	PART
fnp-3453	94	6	compare	compare	VERB
fnp-3453	94	7	how	how	SCONJ
fnp-3453	94	8	the	the	DET
fnp-3453	94	9	sulcus	sulcus	NOUN
fnp-3453	94	10	vs.	vs.	ADP
fnp-3453	94	11	crest	crest	PROPN
fnp-3453	94	12	relative	relative	ADJ
fnp-3453	94	13	ratios	ratio	NOUN
fnp-3453	94	14	of	of	ADP
fnp-3453	94	15	each	each	DET
fnp-3453	94	16	gene	gene	NOUN
fnp-3453	94	17	changed	change	VERB
fnp-3453	94	18	across	across	ADP
fnp-3453	94	19	each	each	DET
fnp-3453	94	20	disease	disease	NOUN
fnp-3453	94	21	group	group	NOUN
fnp-3453	94	22	(	(	PUNCT
fnp-3453	94	23	figure	figure	NOUN
fnp-3453	94	24	1c	1c	NOUN
fnp-3453	94	25	,	,	PUNCT
fnp-3453	94	26	comparison	comparison	NOUN
fnp-3453	94	27	3	3	NUM
fnp-3453	94	28	)	)	PUNCT
fnp-3453	94	29	.	.	PUNCT
fnp-3453	95	1	figure	figure	NOUN
fnp-3453	95	2	1	1	NUM
fnp-3453	95	3	.	.	PUNCT
fnp-3453	96	1	summary	summary	NOUN
fnp-3453	96	2	of	of	ADP
fnp-3453	96	3	differential	differential	ADJ
fnp-3453	96	4	expression	expression	NOUN
fnp-3453	96	5	analysis	analysis	NOUN
fnp-3453	96	6	used	use	VERB
fnp-3453	96	7	for	for	ADP
fnp-3453	96	8	comparisonsrepresentative	comparisonsrepresentative	ADJ
fnp-3453	96	9	images	image	NOUN
fnp-3453	96	10	demonstrating	demonstrate	VERB
fnp-3453	96	11	how	how	SCONJ
fnp-3453	96	12	which	which	DET
fnp-3453	96	13	regions	region	NOUN
fnp-3453	96	14	were	be	AUX
fnp-3453	96	15	being	be	AUX
fnp-3453	96	16	used	use	VERB
fnp-3453	96	17	for	for	ADP
fnp-3453	96	18	comparison	comparison	NOUN
fnp-3453	96	19	.	.	PUNCT
fnp-3453	97	1	a	a	DET
fnp-3453	97	2	)	)	PUNCT
fnp-3453	97	3	comparison	comparison	NOUN
fnp-3453	97	4	1	1	NUM
fnp-3453	97	5	compares	compare	VERB
fnp-3453	97	6	the	the	DET
fnp-3453	97	7	differentially	differentially	ADV
fnp-3453	97	8	expressed	express	VERB
fnp-3453	97	9	genes	gene	NOUN
fnp-3453	97	10	in	in	ADP
fnp-3453	97	11	the	the	DET
fnp-3453	97	12	sulcus	sulcus	NOUN
fnp-3453	97	13	and	and	CCONJ
fnp-3453	97	14	crest	crest	NOUN
fnp-3453	97	15	to	to	ADP
fnp-3453	97	16	the	the	DET
fnp-3453	97	17	corresponding	corresponding	ADJ
fnp-3453	97	18	region	region	NOUN
fnp-3453	97	19	between	between	ADP
fnp-3453	97	20	control	control	PROPN
fnp-3453	97	21	,	,	PUNCT
fnp-3453	97	22	rhi	rhi	PROPN
fnp-3453	97	23	,	,	PUNCT
fnp-3453	97	24	and	and	CCONJ
fnp-3453	97	25	cte	cte	PROPN
fnp-3453	97	26	.	.	PUNCT
fnp-3453	98	1	b	b	X
fnp-3453	98	2	)	)	PUNCT
fnp-3453	98	3	comparison	comparison	NOUN
fnp-3453	98	4	2	2	NUM
fnp-3453	98	5	directly	directly	ADV
fnp-3453	98	6	compares	compare	VERB
fnp-3453	98	7	the	the	DET
fnp-3453	98	8	sulcus	sulcus	NOUN
fnp-3453	98	9	to	to	ADP
fnp-3453	98	10	the	the	DET
fnp-3453	98	11	crest	crest	NOUN
fnp-3453	98	12	within	within	ADP
fnp-3453	98	13	each	each	DET
fnp-3453	98	14	group	group	NOUN
fnp-3453	98	15	.	.	PUNCT
fnp-3453	99	1	c	c	X
fnp-3453	99	2	)	)	PUNCT
fnp-3453	99	3	comparison	comparison	NOUN
fnp-3453	99	4	3	3	NUM
fnp-3453	99	5	uses	use	VERB
fnp-3453	99	6	the	the	DET
fnp-3453	99	7	ratio	ratio	NOUN
fnp-3453	99	8	created	create	VERB
fnp-3453	99	9	from	from	ADP
fnp-3453	99	10	comparison	comparison	NOUN
fnp-3453	99	11	2	2	NUM
fnp-3453	99	12	and	and	CCONJ
fnp-3453	99	13	compares	compare	VERB
fnp-3453	99	14	that	that	SCONJ
fnp-3453	99	15	sulcus	sulcus	NOUN
fnp-3453	99	16	vs	vs	ADP
fnp-3453	99	17	crest	crest	NOUN
fnp-3453	99	18	ratio	ratio	NOUN
fnp-3453	99	19	from	from	ADP
fnp-3453	99	20	rhi	rhi	PROPN
fnp-3453	99	21	and	and	CCONJ
fnp-3453	99	22	cte	cte	NOUN
fnp-3453	99	23	groups	group	NOUN
fnp-3453	99	24	to	to	ADP
fnp-3453	99	25	the	the	DET
fnp-3453	99	26	control	control	NOUN
fnp-3453	99	27	group	group	NOUN
fnp-3453	99	28	to	to	PART
fnp-3453	99	29	determine	determine	VERB
fnp-3453	99	30	how	how	SCONJ
fnp-3453	99	31	the	the	DET
fnp-3453	99	32	sulcal	sulcal	ADJ
fnp-3453	99	33	specific	specific	ADJ
fnp-3453	99	34	genes	gene	NOUN
fnp-3453	99	35	changes	change	VERB
fnp-3453	99	36	over	over	ADP
fnp-3453	99	37	the	the	DET
fnp-3453	99	38	course	course	NOUN
fnp-3453	99	39	of	of	ADP
fnp-3453	99	40	disease	disease	NOUN
fnp-3453	99	41	.	.	PUNCT
fnp-3453	100	1	differentially	differentially	ADV
fnp-3453	100	2	expressed	express	VERB
fnp-3453	100	3	genes	gene	NOUN
fnp-3453	100	4	had	have	VERB
fnp-3453	100	5	similar	similar	ADJ
fnp-3453	100	6	directions	direction	NOUN
fnp-3453	100	7	of	of	ADP
fnp-3453	100	8	effect	effect	NOUN
fnp-3453	100	9	in	in	ADP
fnp-3453	100	10	the	the	DET
fnp-3453	100	11	sulcus	sulcus	NOUN
fnp-3453	100	12	and	and	CCONJ
fnp-3453	100	13	crest	crest	NOUN
fnp-3453	100	14	we	we	PRON
fnp-3453	100	15	first	first	ADV
fnp-3453	100	16	examined	examine	VERB
fnp-3453	100	17	the	the	DET
fnp-3453	100	18	differentially	differentially	ADV
fnp-3453	100	19	expressed	express	VERB
fnp-3453	100	20	(	(	PUNCT
fnp-3453	100	21	de	de	ADJ
fnp-3453	100	22	)	)	PUNCT
fnp-3453	100	23	genes	gene	NOUN
fnp-3453	100	24	found	find	VERB
fnp-3453	100	25	in	in	ADP
fnp-3453	100	26	the	the	DET
fnp-3453	100	27	sulcus	sulcus	NOUN
fnp-3453	100	28	and	and	CCONJ
fnp-3453	100	29	crest	crest	NOUN
fnp-3453	100	30	to	to	PART
fnp-3453	100	31	identify	identify	VERB
fnp-3453	100	32	the	the	DET
fnp-3453	100	33	genes	gene	NOUN
fnp-3453	100	34	most	most	ADV
fnp-3453	100	35	affected	affect	VERB
fnp-3453	100	36	in	in	ADP
fnp-3453	100	37	early	early	ADJ
fnp-3453	100	38	cte	cte	NOUN
fnp-3453	100	39	compared	compare	VERB
fnp-3453	100	40	with	with	ADP
fnp-3453	100	41	control	control	NOUN
fnp-3453	100	42	and	and	CCONJ
fnp-3453	100	43	rhi	rhi	PROPN
fnp-3453	100	44	groups	group	NOUN
fnp-3453	100	45	(	(	PUNCT
fnp-3453	100	46	table	table	NOUN
fnp-3453	100	47	2	2	NUM
fnp-3453	100	48	)	)	PUNCT
fnp-3453	100	49	(	(	PUNCT
fnp-3453	100	50	figure	figure	VERB
fnp-3453	100	51	1a	1a	NOUN
fnp-3453	100	52	,	,	PUNCT
fnp-3453	100	53	comparison	comparison	NOUN
fnp-3453	100	54	1	1	NUM
fnp-3453	100	55	)	)	PUNCT
fnp-3453	100	56	.	.	PUNCT
fnp-3453	101	1	the	the	DET
fnp-3453	101	2	relative	relative	ADJ
fnp-3453	101	3	sulcus	sulcus	NOUN
fnp-3453	101	4	and	and	CCONJ
fnp-3453	101	5	crest	crest	NOUN
fnp-3453	101	6	de	de	NOUN
fnp-3453	101	7	genes	gene	NOUN
fnp-3453	101	8	that	that	PRON
fnp-3453	101	9	were	be	AUX
fnp-3453	101	10	significantly	significantly	ADV
fnp-3453	101	11	altered	alter	VERB
fnp-3453	101	12	(	(	PUNCT
fnp-3453	101	13	nominal	nominal	ADJ
fnp-3453	101	14	p	p	X
fnp-3453	101	15	<	<	X
fnp-3453	101	16	0.05	0.05	NUM
fnp-3453	101	17	)	)	PUNCT
fnp-3453	101	18	in	in	ADP
fnp-3453	101	19	at	at	ADV
fnp-3453	101	20	least	least	ADV
fnp-3453	101	21	one	one	NUM
fnp-3453	101	22	region	region	NOUN
fnp-3453	101	23	were	be	AUX
fnp-3453	101	24	plotted	plot	VERB
fnp-3453	101	25	against	against	ADP
fnp-3453	101	26	each	each	DET
fnp-3453	101	27	other	other	ADJ
fnp-3453	101	28	to	to	PART
fnp-3453	101	29	examine	examine	VERB
fnp-3453	101	30	if	if	SCONJ
fnp-3453	101	31	there	there	PRON
fnp-3453	101	32	were	be	VERB
fnp-3453	101	33	similar	similar	ADJ
fnp-3453	101	34	direction	direction	NOUN
fnp-3453	101	35	changes	change	NOUN
fnp-3453	101	36	occurring	occur	VERB
fnp-3453	101	37	in	in	ADP
fnp-3453	101	38	the	the	DET
fnp-3453	101	39	sulcus	sulcus	NOUN
fnp-3453	101	40	and	and	CCONJ
fnp-3453	101	41	crest	crest	NOUN
fnp-3453	101	42	(	(	PUNCT
fnp-3453	101	43	figure	figure	NOUN
fnp-3453	101	44	2	2	NUM
fnp-3453	101	45	)	)	PUNCT
fnp-3453	101	46	.	.	PUNCT
fnp-3453	102	1	changes	change	NOUN
fnp-3453	102	2	that	that	PRON
fnp-3453	102	3	were	be	AUX
fnp-3453	102	4	consistent	consistent	ADJ
fnp-3453	102	5	across	across	ADP
fnp-3453	102	6	both	both	CCONJ
fnp-3453	102	7	sulcus	sulcus	NOUN
fnp-3453	102	8	and	and	CCONJ
fnp-3453	102	9	crest	crest	NOUN
fnp-3453	102	10	could	could	AUX
fnp-3453	102	11	be	be	AUX
fnp-3453	102	12	interpreted	interpret	VERB
fnp-3453	102	13	as	as	ADP
fnp-3453	102	14	a	a	DET
fnp-3453	102	15	general	general	ADJ
fnp-3453	102	16	frontal	frontal	ADJ
fnp-3453	102	17	cortex	cortex	NOUN
fnp-3453	102	18	wide	wide	ADJ
fnp-3453	102	19	response	response	NOUN
fnp-3453	102	20	.	.	PUNCT
fnp-3453	103	1	first	first	ADV
fnp-3453	103	2	,	,	PUNCT
fnp-3453	103	3	we	we	PRON
fnp-3453	103	4	compared	compare	VERB
fnp-3453	103	5	cte	cte	VERB
fnp-3453	103	6	to	to	PART
fnp-3453	103	7	control	control	VERB
fnp-3453	103	8	(	(	PUNCT
fnp-3453	103	9	figure	figure	NOUN
fnp-3453	103	10	2a	2a	NUM
fnp-3453	103	11	)	)	PUNCT
fnp-3453	103	12	.	.	PUNCT
fnp-3453	104	1	we	we	PRON
fnp-3453	104	2	observed	observe	VERB
fnp-3453	104	3	that	that	SCONJ
fnp-3453	104	4	95	95	NUM
fnp-3453	104	5	%	%	NOUN
fnp-3453	104	6	of	of	ADP
fnp-3453	104	7	genes	gene	NOUN
fnp-3453	104	8	had	have	VERB
fnp-3453	104	9	the	the	DET
fnp-3453	104	10	same	same	ADJ
fnp-3453	104	11	direction	direction	NOUN
fnp-3453	104	12	of	of	ADP
fnp-3453	104	13	effect	effect	NOUN
fnp-3453	104	14	in	in	ADP
fnp-3453	104	15	both	both	CCONJ
fnp-3453	104	16	the	the	DET
fnp-3453	104	17	sulcus	sulcus	NOUN
fnp-3453	104	18	and	and	CCONJ
fnp-3453	104	19	crest	crest	NOUN
fnp-3453	104	20	.	.	PUNCT
fnp-3453	105	1	only	only	ADV
fnp-3453	105	2	109	109	NUM
fnp-3453	105	3	(	(	PUNCT
fnp-3453	105	4	5.0	5.0	NUM
fnp-3453	105	5	%	%	NOUN
fnp-3453	105	6	total	total	ADJ
fnp-3453	105	7	de	de	X
fnp-3453	105	8	genes	gene	NOUN
fnp-3453	105	9	)	)	PUNCT
fnp-3453	105	10	genes	gene	NOUN
fnp-3453	105	11	had	have	VERB
fnp-3453	105	12	an	an	DET
fnp-3453	105	13	opposite	opposite	ADJ
fnp-3453	105	14	direction	direction	NOUN
fnp-3453	105	15	of	of	ADP
fnp-3453	105	16	effect	effect	NOUN
fnp-3453	105	17	(	(	PUNCT
fnp-3453	105	18	figure	figure	NOUN
fnp-3453	105	19	2a	2a	NUM
fnp-3453	105	20	)	)	PUNCT
fnp-3453	105	21	.	.	PUNCT
fnp-3453	106	1	when	when	SCONJ
fnp-3453	106	2	examining	examine	VERB
fnp-3453	106	3	the	the	DET
fnp-3453	106	4	changes	change	NOUN
fnp-3453	106	5	between	between	ADP
fnp-3453	106	6	cte	cte	NOUN
fnp-3453	106	7	and	and	CCONJ
fnp-3453	106	8	rhi	rhi	PROPN
fnp-3453	106	9	,	,	PUNCT
fnp-3453	106	10	we	we	PRON
fnp-3453	106	11	observed	observe	VERB
fnp-3453	106	12	fewer	few	ADJ
fnp-3453	106	13	genes	gene	NOUN
fnp-3453	106	14	were	be	AUX
fnp-3453	106	15	altered	alter	VERB
fnp-3453	106	16	compared	compare	VERB
fnp-3453	106	17	to	to	AUX
fnp-3453	106	18	cte	cte	VERB
fnp-3453	106	19	vs	vs	ADP
fnp-3453	106	20	control	control	NOUN
fnp-3453	106	21	(	(	PUNCT
fnp-3453	106	22	table	table	NOUN
fnp-3453	106	23	2	2	NUM
fnp-3453	106	24	)	)	PUNCT
fnp-3453	106	25	.	.	PUNCT
fnp-3453	107	1	almost	almost	ADV
fnp-3453	107	2	all	all	PRON
fnp-3453	107	3	of	of	ADP
fnp-3453	107	4	the	the	DET
fnp-3453	107	5	genes	gene	NOUN
fnp-3453	107	6	had	have	VERB
fnp-3453	107	7	the	the	DET
fnp-3453	107	8	same	same	ADJ
fnp-3453	107	9	direction	direction	NOUN
fnp-3453	107	10	of	of	ADP
fnp-3453	107	11	effect	effect	NOUN
fnp-3453	107	12	(	(	PUNCT
fnp-3453	107	13	figure	figure	NOUN
fnp-3453	107	14	2b	2b	NOUN
fnp-3453	107	15	)	)	PUNCT
fnp-3453	107	16	.	.	PUNCT
fnp-3453	108	1	only	only	ADV
fnp-3453	108	2	2	2	NUM
fnp-3453	108	3	genes	gene	NOUN
fnp-3453	108	4	(	(	PUNCT
fnp-3453	108	5	0.4	0.4	NUM
fnp-3453	108	6	%	%	NOUN
fnp-3453	108	7	total	total	ADJ
fnp-3453	108	8	de	de	X
fnp-3453	108	9	genes	gene	NOUN
fnp-3453	108	10	)	)	PUNCT
fnp-3453	108	11	,	,	PUNCT
fnp-3453	108	12	jmjd6	jmjd6	PROPN
fnp-3453	108	13	and	and	CCONJ
fnp-3453	108	14	vat1l	vat1l	NUM
fnp-3453	108	15	,	,	PUNCT
fnp-3453	108	16	were	be	AUX
fnp-3453	108	17	elevated	elevate	VERB
fnp-3453	108	18	in	in	ADP
fnp-3453	108	19	the	the	DET
fnp-3453	108	20	sulcus	sulcus	NOUN
fnp-3453	108	21	but	but	CCONJ
fnp-3453	108	22	decreased	decrease	VERB
fnp-3453	108	23	in	in	ADP
fnp-3453	108	24	the	the	DET
fnp-3453	108	25	crest	crest	NOUN
fnp-3453	108	26	.	.	PUNCT
fnp-3453	109	1	the	the	DET
fnp-3453	109	2	genes	gene	NOUN
fnp-3453	109	3	with	with	ADP
fnp-3453	109	4	the	the	DET
fnp-3453	109	5	largest	large	ADJ
fnp-3453	109	6	change	change	NOUN
fnp-3453	109	7	,	,	PUNCT
fnp-3453	109	8	in	in	ADP
fnp-3453	109	9	addition	addition	NOUN
fnp-3453	109	10	to	to	ADP
fnp-3453	109	11	specific	specific	ADJ
fnp-3453	109	12	genes	gene	NOUN
fnp-3453	109	13	of	of	ADP
fnp-3453	109	14	interest	interest	NOUN
fnp-3453	109	15	were	be	AUX
fnp-3453	109	16	highlighted	highlight	VERB
fnp-3453	109	17	.	.	PUNCT
fnp-3453	110	1	a	a	DET
fnp-3453	110	2	full	full	ADJ
fnp-3453	110	3	list	list	NOUN
fnp-3453	110	4	of	of	ADP
fnp-3453	110	5	de	de	ADJ
fnp-3453	110	6	genes	gene	NOUN
fnp-3453	110	7	for	for	ADP
fnp-3453	110	8	the	the	DET
fnp-3453	110	9	cte	cte	NOUN
fnp-3453	110	10	vs	vs	ADP
fnp-3453	110	11	control	control	NOUN
fnp-3453	110	12	and	and	CCONJ
fnp-3453	110	13	cte	cte	PROPN
fnp-3453	110	14	vs	vs	ADP
fnp-3453	110	15	rhi	rhi	PROPN
fnp-3453	110	16	analysis	analysis	NOUN
fnp-3453	110	17	can	can	AUX
fnp-3453	110	18	be	be	AUX
fnp-3453	110	19	found	find	VERB
fnp-3453	110	20	in	in	ADP
fnp-3453	110	21	supplementary	supplementary	ADJ
fnp-3453	110	22	file	file	NOUN
fnp-3453	110	23	1	1	NUM
fnp-3453	110	24	.	.	PUNCT
fnp-3453	110	25	figure	figure	NOUN
fnp-3453	110	26	2	2	NUM
fnp-3453	110	27	.	.	PUNCT
fnp-3453	110	28	comparative	comparative	ADJ
fnp-3453	110	29	analysis	analysis	NOUN
fnp-3453	110	30	of	of	ADP
fnp-3453	110	31	the	the	DET
fnp-3453	110	32	differentially	differentially	ADV
fnp-3453	110	33	expressed	express	VERB
fnp-3453	110	34	genes	gene	NOUN
fnp-3453	110	35	found	find	VERB
fnp-3453	110	36	in	in	ADP
fnp-3453	110	37	the	the	DET
fnp-3453	110	38	sulcus	sulcus	NOUN
fnp-3453	110	39	and	and	CCONJ
fnp-3453	110	40	crestanalysis	crestanalysis	NOUN
fnp-3453	110	41	of	of	ADP
fnp-3453	110	42	de	de	NOUN
fnp-3453	110	43	genes	gene	NOUN
fnp-3453	110	44	from	from	ADP
fnp-3453	110	45	the	the	DET
fnp-3453	110	46	sulcus	sulcus	NOUN
fnp-3453	110	47	and	and	CCONJ
fnp-3453	110	48	crest	crest	NOUN
fnp-3453	110	49	plotted	plot	VERB
fnp-3453	110	50	against	against	ADP
fnp-3453	110	51	each	each	DET
fnp-3453	110	52	other	other	ADJ
fnp-3453	110	53	comparing	compare	VERB
fnp-3453	110	54	(	(	PUNCT
fnp-3453	110	55	a	a	PRON
fnp-3453	110	56	)	)	PUNCT
fnp-3453	110	57	cte	cte	NOUN
fnp-3453	110	58	vs	vs	ADP
fnp-3453	110	59	control	control	NOUN
fnp-3453	110	60	and	and	CCONJ
fnp-3453	110	61	(	(	PUNCT
fnp-3453	110	62	b	b	X
fnp-3453	110	63	)	)	PUNCT
fnp-3453	110	64	cte	cte	NOUN
fnp-3453	110	65	vs	vs	ADP
fnp-3453	110	66	rhi	rhi	PROPN
fnp-3453	110	67	.	.	PUNCT
fnp-3453	111	1	genes	gene	NOUN
fnp-3453	111	2	were	be	AUX
fnp-3453	111	3	plotted	plot	VERB
fnp-3453	111	4	if	if	SCONJ
fnp-3453	111	5	they	they	PRON
fnp-3453	111	6	were	be	AUX
fnp-3453	111	7	significantly	significantly	ADV
fnp-3453	111	8	altered	alter	VERB
fnp-3453	111	9	(	(	PUNCT
fnp-3453	111	10	p<0.05	p<0.05	NOUN
fnp-3453	111	11	)	)	PUNCT
fnp-3453	111	12	in	in	ADP
fnp-3453	111	13	at	at	ADV
fnp-3453	111	14	least	least	ADV
fnp-3453	111	15	one	one	NUM
fnp-3453	111	16	region	region	NOUN
fnp-3453	111	17	.	.	PUNCT
fnp-3453	112	1	each	each	DET
fnp-3453	112	2	dot	dot	NOUN
fnp-3453	112	3	represents	represent	VERB
fnp-3453	112	4	one	one	NUM
fnp-3453	112	5	gene	gene	NOUN
fnp-3453	112	6	.	.	PUNCT
fnp-3453	113	1	genes	gene	NOUN
fnp-3453	113	2	of	of	ADP
fnp-3453	113	3	interest	interest	NOUN
fnp-3453	113	4	and	and	CCONJ
fnp-3453	113	5	the	the	DET
fnp-3453	113	6	top	top	NOUN
fnp-3453	113	7	expressed	express	VERB
fnp-3453	113	8	have	have	AUX
fnp-3453	113	9	been	be	AUX
fnp-3453	113	10	annotated	annotate	VERB
fnp-3453	113	11	.	.	PUNCT
fnp-3453	114	1	gene	gene	NOUN
fnp-3453	114	2	set	set	VERB
fnp-3453	114	3	enrichment	enrichment	NOUN
fnp-3453	114	4	analysis	analysis	NOUN
fnp-3453	114	5	(	(	PUNCT
fnp-3453	114	6	gsea	gsea	NOUN
fnp-3453	114	7	)	)	PUNCT
fnp-3453	114	8	was	be	AUX
fnp-3453	114	9	then	then	ADV
fnp-3453	114	10	performed	perform	VERB
fnp-3453	114	11	on	on	ADP
fnp-3453	114	12	each	each	DET
fnp-3453	114	13	set	set	NOUN
fnp-3453	114	14	of	of	ADP
fnp-3453	114	15	genes	gene	NOUN
fnp-3453	114	16	to	to	PART
fnp-3453	114	17	characterize	characterize	VERB
fnp-3453	114	18	biological	biological	ADJ
fnp-3453	114	19	processes	process	NOUN
fnp-3453	114	20	that	that	PRON
fnp-3453	114	21	are	be	AUX
fnp-3453	114	22	altered	alter	VERB
fnp-3453	114	23	in	in	ADP
fnp-3453	114	24	cte	cte	PROPN
fnp-3453	114	25	(	(	PUNCT
fnp-3453	114	26	table	table	NOUN
fnp-3453	114	27	3	3	NUM
fnp-3453	114	28	)	)	PUNCT
fnp-3453	114	29	.	.	PUNCT
fnp-3453	115	1	each	each	DET
fnp-3453	115	2	gsea	gsea	NOUN
fnp-3453	115	3	process	process	NOUN
fnp-3453	115	4	was	be	AUX
fnp-3453	115	5	then	then	ADV
fnp-3453	115	6	assigned	assign	VERB
fnp-3453	115	7	to	to	ADP
fnp-3453	115	8	1	1	NUM
fnp-3453	115	9	of	of	ADP
fnp-3453	115	10	11	11	NUM
fnp-3453	115	11	overall	overall	ADJ
fnp-3453	115	12	biological	biological	ADJ
fnp-3453	115	13	categories	category	NOUN
fnp-3453	115	14	to	to	PART
fnp-3453	115	15	better	well	ADV
fnp-3453	115	16	contextualize	contextualize	VERB
fnp-3453	115	17	changes	change	NOUN
fnp-3453	115	18	(	(	PUNCT
fnp-3453	115	19	figure	figure	NOUN
fnp-3453	115	20	3	3	NUM
fnp-3453	115	21	)	)	PUNCT
fnp-3453	115	22	.	.	PUNCT
fnp-3453	116	1	when	when	SCONJ
fnp-3453	116	2	comparing	compare	VERB
fnp-3453	116	3	cte	cte	NOUN
fnp-3453	116	4	vs	vs	ADP
fnp-3453	116	5	control	control	NOUN
fnp-3453	116	6	(	(	PUNCT
fnp-3453	116	7	figure	figure	NOUN
fnp-3453	116	8	3a	3a	NUM
fnp-3453	116	9	)	)	PUNCT
fnp-3453	116	10	,	,	PUNCT
fnp-3453	116	11	81	81	NUM
fnp-3453	116	12	processes	process	NOUN
fnp-3453	116	13	were	be	AUX
fnp-3453	116	14	observed	observe	VERB
fnp-3453	116	15	to	to	PART
fnp-3453	116	16	have	have	VERB
fnp-3453	116	17	an	an	DET
fnp-3453	116	18	fdr	fdr	PROPN
fnp-3453	116	19	adjusted	adjust	VERB
fnp-3453	116	20	p	p	X
fnp-3453	116	21	<	<	X
fnp-3453	116	22	0.1	0.1	NUM
fnp-3453	116	23	in	in	ADP
fnp-3453	116	24	the	the	DET
fnp-3453	116	25	sulcus	sulcus	NOUN
fnp-3453	116	26	or	or	CCONJ
fnp-3453	116	27	the	the	DET
fnp-3453	116	28	crest	crest	NOUN
fnp-3453	116	29	.	.	PUNCT
fnp-3453	117	1	41	41	NUM
fnp-3453	117	2	processes	process	NOUN
fnp-3453	117	3	were	be	AUX
fnp-3453	117	4	positively	positively	ADV
fnp-3453	117	5	enriched	enrich	VERB
fnp-3453	117	6	and	and	CCONJ
fnp-3453	117	7	34	34	NUM
fnp-3453	117	8	were	be	AUX
fnp-3453	117	9	negatively	negatively	ADV
fnp-3453	117	10	enriched	enrich	VERB
fnp-3453	117	11	in	in	ADP
fnp-3453	117	12	the	the	DET
fnp-3453	117	13	same	same	ADJ
fnp-3453	117	14	direction	direction	NOUN
fnp-3453	117	15	in	in	ADP
fnp-3453	117	16	both	both	CCONJ
fnp-3453	117	17	the	the	DET
fnp-3453	117	18	sulcus	sulcus	NOUN
fnp-3453	117	19	and	and	CCONJ
fnp-3453	117	20	crest	crest	NOUN
fnp-3453	117	21	.	.	PUNCT
fnp-3453	118	1	a	a	DET
fnp-3453	118	2	complete	complete	ADJ
fnp-3453	118	3	breakdown	breakdown	NOUN
fnp-3453	118	4	of	of	ADP
fnp-3453	118	5	group	group	NOUN
fnp-3453	118	6	assignments	assignment	NOUN
fnp-3453	118	7	can	can	AUX
fnp-3453	118	8	be	be	AUX
fnp-3453	118	9	found	find	VERB
fnp-3453	118	10	in	in	ADP
fnp-3453	118	11	table	table	NOUN
fnp-3453	118	12	3	3	NUM
fnp-3453	118	13	.	.	PUNCT
fnp-3453	119	1	the	the	DET
fnp-3453	119	2	majority	majority	NOUN
fnp-3453	119	3	of	of	ADP
fnp-3453	119	4	positively	positively	ADV
fnp-3453	119	5	enriched	enrich	VERB
fnp-3453	119	6	processes	process	NOUN
fnp-3453	119	7	were	be	AUX
fnp-3453	119	8	involved	involve	VERB
fnp-3453	119	9	the	the	DET
fnp-3453	119	10	immune	immune	ADJ
fnp-3453	119	11	category	category	NOUN
fnp-3453	119	12	with	with	ADP
fnp-3453	119	13	70.7	70.7	NUM
fnp-3453	119	14	%	%	NOUN
fnp-3453	119	15	of	of	ADP
fnp-3453	119	16	total	total	ADJ
fnp-3453	119	17	processes	process	NOUN
fnp-3453	119	18	.	.	PUNCT
fnp-3453	120	1	conversely	conversely	ADV
fnp-3453	120	2	,	,	PUNCT
fnp-3453	120	3	only	only	ADV
fnp-3453	120	4	14.7	14.7	NUM
fnp-3453	120	5	%	%	NOUN
fnp-3453	120	6	of	of	ADP
fnp-3453	120	7	the	the	DET
fnp-3453	120	8	negatively	negatively	ADV
fnp-3453	120	9	enriched	enrich	VERB
fnp-3453	120	10	processes	process	NOUN
fnp-3453	120	11	were	be	AUX
fnp-3453	120	12	immune	immune	ADJ
fnp-3453	120	13	processes	process	NOUN
fnp-3453	120	14	.	.	PUNCT
fnp-3453	121	1	neuronal	neuronal	ADJ
fnp-3453	121	2	processes	process	NOUN
fnp-3453	121	3	were	be	AUX
fnp-3453	121	4	the	the	DET
fnp-3453	121	5	largest	large	ADJ
fnp-3453	121	6	group	group	NOUN
fnp-3453	121	7	of	of	ADP
fnp-3453	121	8	negatively	negatively	ADV
fnp-3453	121	9	enriched	enrich	VERB
fnp-3453	121	10	processes	process	NOUN
fnp-3453	121	11	with	with	ADP
fnp-3453	121	12	35.5	35.5	NUM
fnp-3453	121	13	%	%	NOUN
fnp-3453	121	14	.	.	PUNCT
fnp-3453	122	1	there	there	PRON
fnp-3453	122	2	were	be	VERB
fnp-3453	122	3	fewer	few	ADJ
fnp-3453	122	4	positively	positively	ADV
fnp-3453	122	5	enriched	enrich	VERB
fnp-3453	122	6	neuronal	neuronal	ADJ
fnp-3453	122	7	processes	process	NOUN
fnp-3453	122	8	(	(	PUNCT
fnp-3453	122	9	4.9	4.9	NUM
fnp-3453	122	10	%	%	NOUN
fnp-3453	122	11	)	)	PUNCT
fnp-3453	122	12	.	.	PUNCT
fnp-3453	123	1	most	most	ADJ
fnp-3453	123	2	signaling	signal	VERB
fnp-3453	123	3	processes	process	NOUN
fnp-3453	123	4	were	be	AUX
fnp-3453	123	5	negatively	negatively	ADV
fnp-3453	123	6	enriched	enrich	VERB
fnp-3453	123	7	(	(	PUNCT
fnp-3453	123	8	20.6	20.6	NUM
fnp-3453	123	9	%	%	NOUN
fnp-3453	123	10	)	)	PUNCT
fnp-3453	124	1	compared	compare	VERB
fnp-3453	124	2	to	to	PART
fnp-3453	124	3	positively	positively	ADV
fnp-3453	124	4	enriched	enrich	VERB
fnp-3453	124	5	(	(	PUNCT
fnp-3453	124	6	4.9	4.9	NUM
fnp-3453	124	7	%	%	NOUN
fnp-3453	124	8	)	)	PUNCT
fnp-3453	124	9	.	.	PUNCT
fnp-3453	125	1	mitochondria	mitochondria	PROPN
fnp-3453	125	2	processes	process	NOUN
fnp-3453	125	3	were	be	AUX
fnp-3453	125	4	only	only	ADV
fnp-3453	125	5	found	find	VERB
fnp-3453	125	6	to	to	PART
fnp-3453	125	7	be	be	AUX
fnp-3453	125	8	negatively	negatively	ADV
fnp-3453	125	9	enriched	enrich	VERB
fnp-3453	125	10	,	,	PUNCT
fnp-3453	125	11	while	while	SCONJ
fnp-3453	125	12	vascular	vascular	ADJ
fnp-3453	125	13	processes	process	NOUN
fnp-3453	125	14	were	be	AUX
fnp-3453	125	15	only	only	ADV
fnp-3453	125	16	found	find	VERB
fnp-3453	125	17	in	in	ADP
fnp-3453	125	18	the	the	DET
fnp-3453	125	19	positively	positively	ADV
fnp-3453	125	20	enriched	enrich	VERB
fnp-3453	125	21	group	group	NOUN
fnp-3453	125	22	(	(	PUNCT
fnp-3453	125	23	table	table	NOUN
fnp-3453	125	24	3	3	NUM
fnp-3453	125	25	)	)	PUNCT
fnp-3453	125	26	.	.	PUNCT
fnp-3453	126	1	6	6	NUM
fnp-3453	126	2	processes	process	NOUN
fnp-3453	126	3	were	be	AUX
fnp-3453	126	4	found	find	VERB
fnp-3453	126	5	to	to	PART
fnp-3453	126	6	have	have	VERB
fnp-3453	126	7	a	a	DET
fnp-3453	126	8	mixed	mixed	ADJ
fnp-3453	126	9	direction	direction	NOUN
fnp-3453	126	10	of	of	ADP
fnp-3453	126	11	effect	effect	NOUN
fnp-3453	126	12	.	.	PUNCT
fnp-3453	127	1	of	of	ADP
fnp-3453	127	2	those	those	DET
fnp-3453	127	3	6	6	NUM
fnp-3453	127	4	processes	process	NOUN
fnp-3453	127	5	,	,	PUNCT
fnp-3453	127	6	2	2	NUM
fnp-3453	127	7	were	be	AUX
fnp-3453	127	8	immune	immune	ADJ
fnp-3453	127	9	and	and	CCONJ
fnp-3453	127	10	4	4	NUM
fnp-3453	127	11	were	be	AUX
fnp-3453	127	12	extra	extra	ADJ
fnp-3453	127	13	-	-	ADJ
fnp-3453	127	14	cellular	cellular	ADJ
fnp-3453	127	15	matrix	matrix	NOUN
fnp-3453	127	16	(	(	PUNCT
fnp-3453	127	17	ecm	ecm	PROPN
fnp-3453	127	18	)	)	PUNCT
fnp-3453	127	19	related	relate	VERB
fnp-3453	127	20	(	(	PUNCT
fnp-3453	127	21	table	table	NOUN
fnp-3453	127	22	3	3	NUM
fnp-3453	127	23	)	)	PUNCT
fnp-3453	127	24	.	.	PUNCT
fnp-3453	128	1	for	for	ADP
fnp-3453	128	2	cte	cte	PROPN
fnp-3453	128	3	vs	vs	ADP
fnp-3453	128	4	rhi	rhi	PROPN
fnp-3453	128	5	(	(	PUNCT
fnp-3453	128	6	figure	figure	NOUN
fnp-3453	128	7	3b	3b	NUM
fnp-3453	128	8	)	)	PUNCT
fnp-3453	128	9	,	,	PUNCT
fnp-3453	128	10	44	44	NUM
fnp-3453	128	11	processes	process	NOUN
fnp-3453	128	12	were	be	AUX
fnp-3453	128	13	observed	observe	VERB
fnp-3453	128	14	to	to	PART
fnp-3453	128	15	have	have	VERB
fnp-3453	128	16	an	an	DET
fnp-3453	128	17	fdr	fdr	PROPN
fnp-3453	128	18	adjusted	adjust	VERB
fnp-3453	128	19	p	p	X
fnp-3453	128	20	<	<	X
fnp-3453	128	21	0.1	0.1	NUM
fnp-3453	128	22	in	in	ADP
fnp-3453	128	23	the	the	DET
fnp-3453	128	24	sulcus	sulcus	NOUN
fnp-3453	128	25	or	or	CCONJ
fnp-3453	128	26	crest	crest	NOUN
fnp-3453	128	27	.	.	PUNCT
fnp-3453	129	1	36	36	NUM
fnp-3453	129	2	processes	process	NOUN
fnp-3453	129	3	were	be	AUX
fnp-3453	129	4	positively	positively	ADV
fnp-3453	129	5	enriched	enrich	VERB
fnp-3453	129	6	,	,	PUNCT
fnp-3453	129	7	and	and	CCONJ
fnp-3453	129	8	7	7	NUM
fnp-3453	129	9	processes	process	NOUN
fnp-3453	129	10	were	be	AUX
fnp-3453	129	11	negatively	negatively	ADV
fnp-3453	129	12	enriched	enrich	VERB
fnp-3453	129	13	in	in	ADP
fnp-3453	129	14	the	the	DET
fnp-3453	129	15	same	same	ADJ
fnp-3453	129	16	direction	direction	NOUN
fnp-3453	129	17	.	.	PUNCT
fnp-3453	130	1	the	the	DET
fnp-3453	130	2	largest	large	ADJ
fnp-3453	130	3	positively	positively	ADV
fnp-3453	130	4	enriched	enrich	VERB
fnp-3453	130	5	category	category	NOUN
fnp-3453	130	6	was	be	AUX
fnp-3453	130	7	immune	immune	ADJ
fnp-3453	130	8	processes	process	NOUN
fnp-3453	130	9	with	with	ADP
fnp-3453	130	10	38.9	38.9	NUM
fnp-3453	130	11	%	%	NOUN
fnp-3453	130	12	.	.	PUNCT
fnp-3453	131	1	no	no	DET
fnp-3453	131	2	immune	immune	ADJ
fnp-3453	131	3	processes	process	NOUN
fnp-3453	131	4	were	be	AUX
fnp-3453	131	5	negatively	negatively	ADV
fnp-3453	131	6	enriched	enrich	VERB
fnp-3453	131	7	.	.	PUNCT
fnp-3453	132	1	ecm	ecm	NOUN
fnp-3453	132	2	processes	process	NOUN
fnp-3453	132	3	were	be	AUX
fnp-3453	132	4	the	the	DET
fnp-3453	132	5	second	second	ADV
fnp-3453	132	6	largest	large	ADJ
fnp-3453	132	7	positively	positively	ADV
fnp-3453	132	8	enriched	enrich	VERB
fnp-3453	132	9	category	category	NOUN
fnp-3453	132	10	with	with	ADP
fnp-3453	132	11	30.6	30.6	NUM
fnp-3453	132	12	%	%	NOUN
fnp-3453	132	13	of	of	ADP
fnp-3453	132	14	processes	process	NOUN
fnp-3453	132	15	.	.	PUNCT
fnp-3453	133	1	no	no	DET
fnp-3453	133	2	ecm	ecm	PROPN
fnp-3453	133	3	processes	process	NOUN
fnp-3453	133	4	were	be	AUX
fnp-3453	133	5	negatively	negatively	ADV
fnp-3453	133	6	enriched	enrich	VERB
fnp-3453	133	7	.	.	PUNCT
fnp-3453	134	1	neuronal	neuronal	ADJ
fnp-3453	134	2	processes	process	NOUN
fnp-3453	134	3	were	be	AUX
fnp-3453	134	4	the	the	DET
fnp-3453	134	5	majority	majority	NOUN
fnp-3453	134	6	of	of	ADP
fnp-3453	134	7	negatively	negatively	ADV
fnp-3453	134	8	enriched	enrich	VERB
fnp-3453	134	9	processes	process	NOUN
fnp-3453	134	10	(	(	PUNCT
fnp-3453	134	11	85.7	85.7	NUM
fnp-3453	134	12	%	%	NOUN
fnp-3453	134	13	)	)	PUNCT
fnp-3453	134	14	and	and	CCONJ
fnp-3453	134	15	were	be	AUX
fnp-3453	134	16	higher	high	ADJ
fnp-3453	134	17	than	than	ADP
fnp-3453	134	18	positively	positively	ADV
fnp-3453	134	19	enriched	enrich	VERB
fnp-3453	134	20	neuronal	neuronal	ADJ
fnp-3453	134	21	processes	process	NOUN
fnp-3453	134	22	.	.	PUNCT
fnp-3453	135	1	the	the	DET
fnp-3453	135	2	only	only	ADJ
fnp-3453	135	3	other	other	ADJ
fnp-3453	135	4	negatively	negatively	ADV
fnp-3453	135	5	enriched	enrich	VERB
fnp-3453	135	6	process	process	NOUN
fnp-3453	135	7	was	be	AUX
fnp-3453	135	8	transcription	transcription	NOUN
fnp-3453	135	9	/	/	SYM
fnp-3453	135	10	translation	translation	NOUN
fnp-3453	135	11	(	(	PUNCT
fnp-3453	135	12	14.3	14.3	NUM
fnp-3453	135	13	%	%	NOUN
fnp-3453	135	14	)	)	PUNCT
fnp-3453	135	15	.	.	PUNCT
fnp-3453	136	1	vascular	vascular	ADJ
fnp-3453	136	2	,	,	PUNCT
fnp-3453	136	3	signaling	signaling	ADJ
fnp-3453	136	4	,	,	PUNCT
fnp-3453	136	5	cytoskeletal	cytoskeletal	ADJ
fnp-3453	136	6	,	,	PUNCT
fnp-3453	136	7	endo	endo	NOUN
fnp-3453	136	8	/	/	SYM
fnp-3453	136	9	exocytosis	exocytosis	NOUN
fnp-3453	136	10	,	,	PUNCT
fnp-3453	136	11	and	and	CCONJ
fnp-3453	136	12	other	other	ADJ
fnp-3453	136	13	processes	process	NOUN
fnp-3453	136	14	were	be	AUX
fnp-3453	136	15	all	all	PRON
fnp-3453	136	16	similarly	similarly	ADV
fnp-3453	136	17	expressed	express	VERB
fnp-3453	136	18	.	.	PUNCT
fnp-3453	137	1	one	one	NUM
fnp-3453	137	2	process	process	NOUN
fnp-3453	137	3	,	,	PUNCT
fnp-3453	137	4	“	"	PUNCT
fnp-3453	137	5	signaling	signal	VERB
fnp-3453	137	6	receptor	receptor	NOUN
fnp-3453	137	7	activity	activity	NOUN
fnp-3453	137	8	”	"	PUNCT
fnp-3453	137	9	,	,	PUNCT
fnp-3453	137	10	from	from	ADP
fnp-3453	137	11	the	the	DET
fnp-3453	137	12	signaling	signal	VERB
fnp-3453	137	13	category	category	NOUN
fnp-3453	137	14	,	,	PUNCT
fnp-3453	137	15	was	be	AUX
fnp-3453	137	16	decreased	decrease	VERB
fnp-3453	137	17	in	in	ADP
fnp-3453	137	18	the	the	DET
fnp-3453	137	19	crest	crest	NOUN
fnp-3453	137	20	and	and	CCONJ
fnp-3453	137	21	increased	increase	VERB
fnp-3453	137	22	in	in	ADP
fnp-3453	137	23	the	the	DET
fnp-3453	137	24	sulcus	sulcus	NOUN
fnp-3453	137	25	(	(	PUNCT
fnp-3453	137	26	figure	figure	NOUN
fnp-3453	137	27	3	3	NUM
fnp-3453	137	28	)	)	PUNCT
fnp-3453	137	29	.	.	PUNCT
fnp-3453	138	1	figure	figure	VERB
fnp-3453	138	2	3	3	NUM
fnp-3453	138	3	.	.	X
fnp-3453	138	4	heatmap	heatmap	NOUN
fnp-3453	138	5	of	of	ADP
fnp-3453	138	6	sulcus	sulcus	NOUN
fnp-3453	138	7	and	and	CCONJ
fnp-3453	138	8	crest	crest	NOUN
fnp-3453	138	9	gsea	gsea	NOUN
fnp-3453	138	10	biological	biological	ADJ
fnp-3453	138	11	processesusing	processesuse	VERB
fnp-3453	138	12	the	the	DET
fnp-3453	138	13	de	de	ADJ
fnp-3453	138	14	genes	gene	NOUN
fnp-3453	138	15	from	from	ADP
fnp-3453	138	16	the	the	DET
fnp-3453	138	17	sulcus	sulcus	NOUN
fnp-3453	138	18	and	and	CCONJ
fnp-3453	138	19	crest	crest	NOUN
fnp-3453	138	20	,	,	PUNCT
fnp-3453	138	21	gsea	gsea	ADJ
fnp-3453	138	22	biological	biological	ADJ
fnp-3453	138	23	processes	process	NOUN
fnp-3453	138	24	were	be	AUX
fnp-3453	138	25	derived	derive	VERB
fnp-3453	138	26	and	and	CCONJ
fnp-3453	138	27	plotted	plot	VERB
fnp-3453	138	28	in	in	ADP
fnp-3453	138	29	a	a	DET
fnp-3453	138	30	heatmap	heatmap	NOUN
fnp-3453	138	31	comparing	compare	VERB
fnp-3453	138	32	(	(	PUNCT
fnp-3453	138	33	a	a	PRON
fnp-3453	138	34	)	)	PUNCT
fnp-3453	138	35	cte	cte	NOUN
fnp-3453	138	36	vs	vs	ADP
fnp-3453	138	37	control	control	NOUN
fnp-3453	138	38	and	and	CCONJ
fnp-3453	138	39	(	(	PUNCT
fnp-3453	138	40	b	b	X
fnp-3453	138	41	)	)	PUNCT
fnp-3453	138	42	cte	cte	NOUN
fnp-3453	138	43	vs	vs	ADP
fnp-3453	138	44	rhi	rhi	PROPN
fnp-3453	138	45	.	.	PUNCT
fnp-3453	139	1	processes	process	NOUN
fnp-3453	139	2	were	be	AUX
fnp-3453	139	3	included	include	VERB
fnp-3453	139	4	if	if	SCONJ
fnp-3453	139	5	they	they	PRON
fnp-3453	139	6	were	be	AUX
fnp-3453	139	7	significantly	significantly	ADV
fnp-3453	139	8	enriched	enrich	VERB
fnp-3453	139	9	(	(	PUNCT
fnp-3453	139	10	fdr	fdr	PROPN
fnp-3453	139	11	adjusted	adjust	VERB
fnp-3453	139	12	p	p	PRON
fnp-3453	139	13	<	<	X
fnp-3453	139	14	0.1	0.1	NUM
fnp-3453	139	15	)	)	PUNCT
fnp-3453	139	16	in	in	ADP
fnp-3453	139	17	at	at	ADV
fnp-3453	139	18	least	least	ADV
fnp-3453	139	19	one	one	NUM
fnp-3453	139	20	region	region	NOUN
fnp-3453	139	21	.	.	PUNCT
fnp-3453	140	1	each	each	DET
fnp-3453	140	2	gsea	gsea	ADJ
fnp-3453	140	3	biological	biological	ADJ
fnp-3453	140	4	process	process	NOUN
fnp-3453	140	5	was	be	AUX
fnp-3453	140	6	assigned	assign	VERB
fnp-3453	140	7	to	to	ADP
fnp-3453	140	8	1	1	NUM
fnp-3453	140	9	of	of	ADP
fnp-3453	140	10	11	11	NUM
fnp-3453	140	11	biological	biological	ADJ
fnp-3453	140	12	categories	category	NOUN
fnp-3453	140	13	to	to	PART
fnp-3453	140	14	better	well	ADV
fnp-3453	140	15	identify	identify	VERB
fnp-3453	140	16	overall	overall	ADJ
fnp-3453	140	17	changes	change	NOUN
fnp-3453	140	18	.	.	PUNCT
fnp-3453	141	1	[	[	X
fnp-3453	141	2	please	please	INTJ
fnp-3453	141	3	click	click	VERB
fnp-3453	141	4	on	on	ADP
fnp-3453	141	5	the	the	DET
fnp-3453	141	6	figure	figure	NOUN
fnp-3453	141	7	to	to	PART
fnp-3453	141	8	download	download	VERB
fnp-3453	141	9	a	a	DET
fnp-3453	141	10	high	high	ADJ
fnp-3453	141	11	-	-	PUNCT
fnp-3453	141	12	resolution	resolution	NOUN
fnp-3453	141	13	version	version	NOUN
fnp-3453	141	14	]	]	PUNCT
fnp-3453	141	15	there	there	PRON
fnp-3453	141	16	were	be	VERB
fnp-3453	141	17	significant	significant	ADJ
fnp-3453	141	18	differences	difference	NOUN
fnp-3453	141	19	in	in	ADP
fnp-3453	141	20	the	the	DET
fnp-3453	141	21	sulcus	sulcus	NOUN
fnp-3453	141	22	compared	compare	VERB
fnp-3453	141	23	to	to	ADP
fnp-3453	141	24	the	the	DET
fnp-3453	141	25	crest	crest	NOUN
fnp-3453	141	26	we	we	PRON
fnp-3453	141	27	next	next	ADV
fnp-3453	141	28	chose	choose	VERB
fnp-3453	141	29	to	to	PART
fnp-3453	141	30	directly	directly	ADV
fnp-3453	141	31	compare	compare	VERB
fnp-3453	141	32	the	the	DET
fnp-3453	141	33	sulcus	sulcus	NOUN
fnp-3453	141	34	and	and	CCONJ
fnp-3453	141	35	crest	crest	NOUN
fnp-3453	141	36	within	within	ADP
fnp-3453	141	37	the	the	DET
fnp-3453	141	38	controls	control	NOUN
fnp-3453	141	39	,	,	PUNCT
fnp-3453	141	40	rhi	rhi	PROPN
fnp-3453	141	41	,	,	PUNCT
fnp-3453	141	42	and	and	CCONJ
fnp-3453	141	43	cte	cte	NOUN
fnp-3453	141	44	groups	group	NOUN
fnp-3453	141	45	to	to	PART
fnp-3453	141	46	determine	determine	VERB
fnp-3453	141	47	which	which	DET
fnp-3453	141	48	genes	gene	NOUN
fnp-3453	141	49	were	be	AUX
fnp-3453	141	50	specifically	specifically	ADV
fnp-3453	141	51	altered	alter	VERB
fnp-3453	141	52	in	in	ADP
fnp-3453	141	53	the	the	DET
fnp-3453	141	54	sulcus	sulcus	NOUN
fnp-3453	141	55	compared	compare	VERB
fnp-3453	141	56	with	with	ADP
fnp-3453	141	57	the	the	DET
fnp-3453	141	58	crest	crest	NOUN
fnp-3453	141	59	by	by	ADP
fnp-3453	141	60	computing	compute	VERB
fnp-3453	141	61	an	an	DET
fnp-3453	141	62	arcsin	arcsin	PROPN
fnp-3453	141	63	transformed	transform	VERB
fnp-3453	141	64	log2	log2	PROPN
fnp-3453	141	65	ratio	ratio	NOUN
fnp-3453	141	66	of	of	ADP
fnp-3453	141	67	sulcus	sulcus	NOUN
fnp-3453	141	68	vs	vs	ADP
fnp-3453	141	69	crest	crest	NOUN
fnp-3453	141	70	normalized	normalize	VERB
fnp-3453	141	71	counts	count	NOUN
fnp-3453	141	72	within	within	ADP
fnp-3453	141	73	individuals	individual	NOUN
fnp-3453	141	74	(	(	PUNCT
fnp-3453	141	75	see	see	VERB
fnp-3453	141	76	methods	method	NOUN
fnp-3453	141	77	)	)	PUNCT
fnp-3453	141	78	(	(	PUNCT
fnp-3453	141	79	table	table	NOUN
fnp-3453	141	80	4	4	NUM
fnp-3453	141	81	)	)	PUNCT
fnp-3453	141	82	(	(	PUNCT
fnp-3453	141	83	figure	figure	VERB
fnp-3453	141	84	1b	1b	NUM
fnp-3453	141	85	,	,	PUNCT
fnp-3453	141	86	comparison	comparison	NOUN
fnp-3453	141	87	2	2	NUM
fnp-3453	141	88	)	)	PUNCT
fnp-3453	141	89	.	.	PUNCT
fnp-3453	142	1	alterations	alteration	NOUN
fnp-3453	142	2	within	within	ADP
fnp-3453	142	3	each	each	DET
fnp-3453	142	4	group	group	NOUN
fnp-3453	142	5	could	could	AUX
fnp-3453	142	6	be	be	AUX
fnp-3453	142	7	related	relate	VERB
fnp-3453	142	8	to	to	ADP
fnp-3453	142	9	the	the	DET
fnp-3453	142	10	unique	unique	ADJ
fnp-3453	142	11	aspects	aspect	NOUN
fnp-3453	142	12	of	of	ADP
fnp-3453	142	13	each	each	DET
fnp-3453	142	14	condition	condition	NOUN
fnp-3453	142	15	.	.	PUNCT
fnp-3453	143	1	changes	change	NOUN
fnp-3453	143	2	in	in	ADP
fnp-3453	143	3	the	the	DET
fnp-3453	143	4	control	control	NOUN
fnp-3453	143	5	sulcus	sulcus	NOUN
fnp-3453	143	6	are	be	AUX
fnp-3453	143	7	related	relate	VERB
fnp-3453	143	8	to	to	ADP
fnp-3453	143	9	general	general	ADJ
fnp-3453	143	10	anatomy	anatomy	NOUN
fnp-3453	143	11	,	,	PUNCT
fnp-3453	143	12	rhi	rhi	PROPN
fnp-3453	143	13	sulcal	sulcal	ADJ
fnp-3453	143	14	changes	change	NOUN
fnp-3453	143	15	are	be	AUX
fnp-3453	143	16	related	relate	VERB
fnp-3453	143	17	to	to	ADP
fnp-3453	143	18	repetitive	repetitive	ADJ
fnp-3453	143	19	head	head	NOUN
fnp-3453	143	20	trauma	trauma	NOUN
fnp-3453	143	21	induced	induce	VERB
fnp-3453	143	22	damage	damage	NOUN
fnp-3453	143	23	,	,	PUNCT
fnp-3453	143	24	and	and	CCONJ
fnp-3453	143	25	cte	cte	PROPN
fnp-3453	143	26	sulcal	sulcal	ADJ
fnp-3453	143	27	changes	change	NOUN
fnp-3453	143	28	were	be	AUX
fnp-3453	143	29	related	relate	VERB
fnp-3453	143	30	to	to	ADP
fnp-3453	143	31	p	p	NOUN
fnp-3453	143	32	-	-	PUNCT
fnp-3453	143	33	tau	tau	NOUN
fnp-3453	143	34	deposition	deposition	NOUN
fnp-3453	143	35	.	.	PUNCT
fnp-3453	144	1	within	within	ADP
fnp-3453	144	2	controls	control	NOUN
fnp-3453	144	3	,	,	PUNCT
fnp-3453	144	4	we	we	PRON
fnp-3453	144	5	observed	observe	VERB
fnp-3453	144	6	671	671	NUM
fnp-3453	144	7	genes	gene	NOUN
fnp-3453	144	8	had	have	VERB
fnp-3453	144	9	an	an	DET
fnp-3453	144	10	fdr	fdr	PROPN
fnp-3453	144	11	adjusted	adjust	VERB
fnp-3453	144	12	p	p	X
fnp-3453	144	13	<	<	X
fnp-3453	144	14	0.1	0.1	NUM
fnp-3453	144	15	.	.	PUNCT
fnp-3453	145	1	of	of	ADP
fnp-3453	145	2	the	the	DET
fnp-3453	145	3	fdr	fdr	PROPN
fnp-3453	145	4	corrected	correct	VERB
fnp-3453	145	5	genes	gene	NOUN
fnp-3453	145	6	,	,	PUNCT
fnp-3453	145	7	579	579	NUM
fnp-3453	145	8	were	be	AUX
fnp-3453	145	9	increased	increase	VERB
fnp-3453	145	10	in	in	ADP
fnp-3453	145	11	the	the	DET
fnp-3453	145	12	sulcus	sulcus	NOUN
fnp-3453	145	13	and	and	CCONJ
fnp-3453	145	14	92	92	NUM
fnp-3453	145	15	were	be	AUX
fnp-3453	145	16	decreased	decrease	VERB
fnp-3453	145	17	in	in	ADP
fnp-3453	145	18	the	the	DET
fnp-3453	145	19	sulcus	sulcus	NOUN
fnp-3453	145	20	compared	compare	VERB
fnp-3453	145	21	to	to	ADP
fnp-3453	145	22	the	the	DET
fnp-3453	145	23	crest	crest	NOUN
fnp-3453	145	24	(	(	PUNCT
fnp-3453	145	25	figure	figure	NOUN
fnp-3453	145	26	4a	4a	NUM
fnp-3453	145	27	)	)	PUNCT
fnp-3453	145	28	.	.	PUNCT
fnp-3453	146	1	for	for	ADP
fnp-3453	146	2	cases	case	NOUN
fnp-3453	146	3	in	in	ADP
fnp-3453	146	4	the	the	DET
fnp-3453	146	5	rhi	rhi	PROPN
fnp-3453	146	6	group	group	PROPN
fnp-3453	146	7	,	,	PUNCT
fnp-3453	146	8	1926	1926	NUM
fnp-3453	146	9	genes	gene	NOUN
fnp-3453	146	10	were	be	AUX
fnp-3453	146	11	found	find	VERB
fnp-3453	146	12	to	to	PART
fnp-3453	146	13	have	have	VERB
fnp-3453	146	14	a	a	DET
fnp-3453	146	15	nominal	nominal	ADJ
fnp-3453	146	16	p	p	X
fnp-3453	146	17	<	<	X
fnp-3453	146	18	0.05	0.05	NUM
fnp-3453	146	19	.	.	PUNCT
fnp-3453	147	1	however	however	ADV
fnp-3453	147	2	,	,	PUNCT
fnp-3453	147	3	only	only	ADV
fnp-3453	147	4	1	1	NUM
fnp-3453	147	5	gene	gene	NOUN
fnp-3453	147	6	,	,	PUNCT
fnp-3453	147	7	manea	manea	PROPN
fnp-3453	147	8	,	,	PUNCT
fnp-3453	147	9	reached	reach	VERB
fnp-3453	147	10	fdr	fdr	PROPN
fnp-3453	147	11	corrected	correct	VERB
fnp-3453	147	12	significance	significance	NOUN
fnp-3453	147	13	.	.	PUNCT
fnp-3453	148	1	of	of	ADP
fnp-3453	148	2	the	the	DET
fnp-3453	148	3	nominally	nominally	ADV
fnp-3453	148	4	significant	significant	ADJ
fnp-3453	148	5	genes	gene	NOUN
fnp-3453	148	6	,	,	PUNCT
fnp-3453	148	7	1127	1127	NUM
fnp-3453	148	8	were	be	AUX
fnp-3453	148	9	increased	increase	VERB
fnp-3453	148	10	and	and	CCONJ
fnp-3453	148	11	799	799	NUM
fnp-3453	148	12	were	be	AUX
fnp-3453	148	13	decreased	decrease	VERB
fnp-3453	148	14	in	in	ADP
fnp-3453	148	15	the	the	DET
fnp-3453	148	16	sulcus	sulcus	NOUN
fnp-3453	148	17	compared	compare	VERB
fnp-3453	148	18	to	to	ADP
fnp-3453	148	19	the	the	DET
fnp-3453	148	20	crest	crest	NOUN
fnp-3453	148	21	(	(	PUNCT
fnp-3453	148	22	figure	figure	VERB
fnp-3453	148	23	4b	4b	PROPN
fnp-3453	148	24	)	)	PUNCT
fnp-3453	148	25	.	.	PUNCT
fnp-3453	149	1	in	in	ADP
fnp-3453	149	2	subjects	subject	NOUN
fnp-3453	149	3	with	with	ADP
fnp-3453	149	4	cte	cte	NOUN
fnp-3453	149	5	,	,	PUNCT
fnp-3453	149	6	1147	1147	NUM
fnp-3453	149	7	genes	gene	NOUN
fnp-3453	149	8	reached	reach	VERB
fnp-3453	149	9	fdr	fdr	PROPN
fnp-3453	149	10	adjusted	adjust	VERB
fnp-3453	149	11	p	p	PRON
fnp-3453	149	12	<	<	X
fnp-3453	149	13	0.1	0.1	NUM
fnp-3453	149	14	.	.	PUNCT
fnp-3453	150	1	603	603	NUM
fnp-3453	150	2	genes	gene	NOUN
fnp-3453	150	3	were	be	AUX
fnp-3453	150	4	elevated	elevate	VERB
fnp-3453	150	5	in	in	ADP
fnp-3453	150	6	the	the	DET
fnp-3453	150	7	sulcus	sulcus	NOUN
fnp-3453	150	8	and	and	CCONJ
fnp-3453	150	9	433	433	NUM
fnp-3453	150	10	genes	gene	NOUN
fnp-3453	150	11	were	be	AUX
fnp-3453	150	12	decreased	decrease	VERB
fnp-3453	150	13	in	in	ADP
fnp-3453	150	14	the	the	DET
fnp-3453	150	15	sulcus	sulcus	NOUN
fnp-3453	150	16	compared	compare	VERB
fnp-3453	150	17	to	to	ADP
fnp-3453	150	18	the	the	DET
fnp-3453	150	19	crest	crest	NOUN
fnp-3453	150	20	(	(	PUNCT
fnp-3453	150	21	figure	figure	NOUN
fnp-3453	150	22	4c	4c	NOUN
fnp-3453	150	23	)	)	PUNCT
fnp-3453	150	24	.	.	PUNCT
fnp-3453	151	1	the	the	DET
fnp-3453	151	2	top	top	ADJ
fnp-3453	151	3	10	10	NUM
fnp-3453	151	4	increased	increase	VERB
fnp-3453	151	5	and	and	CCONJ
fnp-3453	151	6	decreased	decrease	VERB
fnp-3453	151	7	genes	gene	NOUN
fnp-3453	151	8	by	by	ADP
fnp-3453	151	9	log2	log2	PROPN
fnp-3453	151	10	fold	fold	NOUN
fnp-3453	151	11	change	change	NOUN
fnp-3453	151	12	were	be	AUX
fnp-3453	151	13	annotated	annotate	VERB
fnp-3453	151	14	in	in	ADP
fnp-3453	151	15	each	each	DET
fnp-3453	151	16	plot	plot	NOUN
fnp-3453	151	17	.	.	PUNCT
fnp-3453	152	1	a	a	DET
fnp-3453	152	2	full	full	ADJ
fnp-3453	152	3	list	list	NOUN
fnp-3453	152	4	of	of	ADP
fnp-3453	152	5	sulcus	sulcus	NOUN
fnp-3453	152	6	vs.	vs.	ADP
fnp-3453	152	7	crest	crest	NOUN
fnp-3453	152	8	gene	gene	NOUN
fnp-3453	152	9	changes	change	NOUN
fnp-3453	152	10	can	can	AUX
fnp-3453	152	11	be	be	AUX
fnp-3453	152	12	found	find	VERB
fnp-3453	152	13	in	in	ADP
fnp-3453	152	14	supplementary	supplementary	ADJ
fnp-3453	152	15	file	file	NOUN
fnp-3453	152	16	2	2	NUM
fnp-3453	152	17	.	.	X
fnp-3453	152	18	figure	figure	NOUN
fnp-3453	152	19	4	4	NUM
fnp-3453	152	20	.	.	PUNCT
fnp-3453	152	21	genes	gene	NOUN
fnp-3453	152	22	that	that	PRON
fnp-3453	152	23	are	be	AUX
fnp-3453	152	24	differentially	differentially	ADV
fnp-3453	152	25	expressed	express	VERB
fnp-3453	152	26	in	in	ADP
fnp-3453	152	27	the	the	DET
fnp-3453	152	28	sulcus	sulcus	NOUN
fnp-3453	152	29	compared	compare	VERB
fnp-3453	152	30	to	to	ADP
fnp-3453	152	31	the	the	DET
fnp-3453	152	32	crestthe	crestthe	PROPN
fnp-3453	152	33	sulcus	sulcus	NOUN
fnp-3453	152	34	was	be	AUX
fnp-3453	152	35	directly	directly	ADV
fnp-3453	152	36	compared	compare	VERB
fnp-3453	152	37	to	to	ADP
fnp-3453	152	38	the	the	DET
fnp-3453	152	39	crest	crest	NOUN
fnp-3453	152	40	across	across	ADP
fnp-3453	152	41	(	(	PUNCT
fnp-3453	152	42	a	a	PRON
fnp-3453	152	43	)	)	PUNCT
fnp-3453	152	44	control	control	NOUN
fnp-3453	152	45	,	,	PUNCT
fnp-3453	152	46	(	(	PUNCT
fnp-3453	152	47	b	b	X
fnp-3453	152	48	)	)	PUNCT
fnp-3453	152	49	rhi	rhi	NOUN
fnp-3453	152	50	,	,	PUNCT
fnp-3453	152	51	and	and	CCONJ
fnp-3453	152	52	(	(	PUNCT
fnp-3453	152	53	c	c	X
fnp-3453	152	54	)	)	PUNCT
fnp-3453	152	55	cte	cte	NOUN
fnp-3453	152	56	and	and	CCONJ
fnp-3453	152	57	sulcal	sulcal	ADV
fnp-3453	152	58	specific	specific	ADJ
fnp-3453	152	59	de	de	NOUN
fnp-3453	152	60	genes	gene	NOUN
fnp-3453	152	61	were	be	AUX
fnp-3453	152	62	calculated	calculate	VERB
fnp-3453	152	63	.	.	PUNCT
fnp-3453	153	1	each	each	DET
fnp-3453	153	2	dot	dot	NOUN
fnp-3453	153	3	represents	represent	VERB
fnp-3453	153	4	one	one	NUM
fnp-3453	153	5	gene	gene	NOUN
fnp-3453	153	6	.	.	PUNCT
fnp-3453	154	1	dots	dot	NOUN
fnp-3453	154	2	that	that	PRON
fnp-3453	154	3	are	be	AUX
fnp-3453	154	4	red	red	ADJ
fnp-3453	154	5	represent	represent	NOUN
fnp-3453	154	6	genes	gene	NOUN
fnp-3453	154	7	that	that	PRON
fnp-3453	154	8	met	meet	VERB
fnp-3453	154	9	fdr	fdr	PROPN
fnp-3453	154	10	adjusted	adjust	VERB
fnp-3453	154	11	p	p	X
fnp-3453	154	12	<	<	X
fnp-3453	154	13	0.1	0.1	NUM
fnp-3453	154	14	significance	significance	NOUN
fnp-3453	154	15	.	.	PUNCT
fnp-3453	155	1	the	the	DET
fnp-3453	155	2	top	top	ADJ
fnp-3453	155	3	10	10	NUM
fnp-3453	155	4	positive	positive	ADJ
fnp-3453	155	5	and	and	CCONJ
fnp-3453	155	6	negatively	negatively	ADV
fnp-3453	155	7	enriched	enrich	VERB
fnp-3453	155	8	genes	gene	NOUN
fnp-3453	155	9	were	be	AUX
fnp-3453	155	10	annotated	annotate	VERB
fnp-3453	155	11	.	.	PUNCT
fnp-3453	156	1	gsea	gsea	NOUN
fnp-3453	156	2	analysis	analysis	NOUN
fnp-3453	156	3	clarifies	clarify	VERB
fnp-3453	156	4	biological	biological	ADJ
fnp-3453	156	5	response	response	NOUN
fnp-3453	156	6	processes	process	NOUN
fnp-3453	156	7	that	that	PRON
fnp-3453	156	8	are	be	AUX
fnp-3453	156	9	occurring	occur	VERB
fnp-3453	156	10	in	in	ADP
fnp-3453	156	11	the	the	DET
fnp-3453	156	12	sulcus	sulcus	NOUN
fnp-3453	156	13	in	in	ADP
fnp-3453	156	14	each	each	DET
fnp-3453	156	15	condition	condition	NOUN
fnp-3453	156	16	to	to	PART
fnp-3453	156	17	further	far	ADV
fnp-3453	156	18	explore	explore	VERB
fnp-3453	156	19	how	how	SCONJ
fnp-3453	156	20	the	the	DET
fnp-3453	156	21	sulcal	sulcal	ADJ
fnp-3453	156	22	specific	specific	ADJ
fnp-3453	156	23	response	response	NOUN
fnp-3453	156	24	contributed	contribute	VERB
fnp-3453	156	25	to	to	ADP
fnp-3453	156	26	the	the	DET
fnp-3453	156	27	larger	large	ADJ
fnp-3453	156	28	biological	biological	ADJ
fnp-3453	156	29	response	response	NOUN
fnp-3453	156	30	,	,	PUNCT
fnp-3453	156	31	gsea	gsea	NOUN
fnp-3453	156	32	was	be	AUX
fnp-3453	156	33	performed	perform	VERB
fnp-3453	156	34	using	use	VERB
fnp-3453	156	35	the	the	DET
fnp-3453	156	36	genes	gene	NOUN
fnp-3453	156	37	that	that	PRON
fnp-3453	156	38	were	be	AUX
fnp-3453	156	39	significantly	significantly	ADV
fnp-3453	156	40	altered	alter	VERB
fnp-3453	156	41	in	in	ADP
fnp-3453	156	42	the	the	DET
fnp-3453	156	43	sulcus	sulcus	NOUN
fnp-3453	156	44	compared	compare	VERB
fnp-3453	156	45	to	to	ADP
fnp-3453	156	46	the	the	DET
fnp-3453	156	47	crest	crest	NOUN
fnp-3453	156	48	.	.	PUNCT
fnp-3453	157	1	using	use	VERB
fnp-3453	157	2	fdr	fdr	PROPN
fnp-3453	157	3	adjusted	adjust	VERB
fnp-3453	157	4	p	p	PRON
fnp-3453	157	5	<	<	X
fnp-3453	157	6	0.1	0.1	NUM
fnp-3453	157	7	,	,	PUNCT
fnp-3453	157	8	301	301	NUM
fnp-3453	157	9	significant	significant	ADJ
fnp-3453	157	10	processes	process	NOUN
fnp-3453	157	11	were	be	AUX
fnp-3453	157	12	observed	observe	VERB
fnp-3453	157	13	in	in	ADP
fnp-3453	157	14	controls	control	NOUN
fnp-3453	157	15	,	,	PUNCT
fnp-3453	157	16	78	78	NUM
fnp-3453	157	17	in	in	ADP
fnp-3453	157	18	rhi	rhi	NOUN
fnp-3453	157	19	,	,	PUNCT
fnp-3453	157	20	and	and	CCONJ
fnp-3453	157	21	129	129	NUM
fnp-3453	157	22	in	in	ADP
fnp-3453	157	23	cte	cte	PROPN
fnp-3453	157	24	.	.	PUNCT
fnp-3453	158	1	the	the	DET
fnp-3453	158	2	observed	observe	VERB
fnp-3453	158	3	processes	process	NOUN
fnp-3453	158	4	represented	represent	VERB
fnp-3453	158	5	biological	biological	ADJ
fnp-3453	158	6	changes	change	NOUN
fnp-3453	158	7	specific	specific	ADJ
fnp-3453	158	8	to	to	ADP
fnp-3453	158	9	the	the	DET
fnp-3453	158	10	sulcus	sulcus	NOUN
fnp-3453	158	11	compared	compare	VERB
fnp-3453	158	12	to	to	ADP
fnp-3453	158	13	the	the	DET
fnp-3453	158	14	crest	crest	NOUN
fnp-3453	158	15	in	in	ADP
fnp-3453	158	16	each	each	DET
fnp-3453	158	17	relative	relative	ADJ
fnp-3453	158	18	group	group	NOUN
fnp-3453	158	19	.	.	PUNCT
fnp-3453	159	1	we	we	PRON
fnp-3453	159	2	then	then	ADV
fnp-3453	159	3	wanted	want	VERB
fnp-3453	159	4	to	to	PART
fnp-3453	159	5	compare	compare	VERB
fnp-3453	159	6	enrichment	enrichment	NOUN
fnp-3453	159	7	of	of	ADP
fnp-3453	159	8	each	each	DET
fnp-3453	159	9	biological	biological	ADJ
fnp-3453	159	10	process	process	NOUN
fnp-3453	159	11	across	across	ADP
fnp-3453	159	12	groups	group	NOUN
fnp-3453	159	13	and	and	CCONJ
fnp-3453	159	14	determine	determine	VERB
fnp-3453	159	15	if	if	SCONJ
fnp-3453	159	16	there	there	PRON
fnp-3453	159	17	were	be	VERB
fnp-3453	159	18	similar	similar	ADJ
fnp-3453	159	19	or	or	CCONJ
fnp-3453	159	20	different	different	ADJ
fnp-3453	159	21	directions	direction	NOUN
fnp-3453	159	22	of	of	ADP
fnp-3453	159	23	effect	effect	NOUN
fnp-3453	159	24	(	(	PUNCT
fnp-3453	159	25	figure	figure	NOUN
fnp-3453	159	26	5	5	NUM
fnp-3453	159	27	)	)	PUNCT
fnp-3453	159	28	.	.	PUNCT
fnp-3453	160	1	for	for	ADP
fnp-3453	160	2	added	add	VERB
fnp-3453	160	3	clarity	clarity	NOUN
fnp-3453	160	4	and	and	CCONJ
fnp-3453	160	5	biological	biological	ADJ
fnp-3453	160	6	relevance	relevance	NOUN
fnp-3453	160	7	,	,	PUNCT
fnp-3453	160	8	each	each	DET
fnp-3453	160	9	process	process	NOUN
fnp-3453	160	10	was	be	AUX
fnp-3453	160	11	assigned	assign	VERB
fnp-3453	160	12	to	to	ADP
fnp-3453	160	13	1	1	NUM
fnp-3453	160	14	of	of	ADP
fnp-3453	160	15	11	11	NUM
fnp-3453	160	16	greater	great	ADJ
fnp-3453	160	17	biological	biological	ADJ
fnp-3453	160	18	categories	category	NOUN
fnp-3453	160	19	similar	similar	ADJ
fnp-3453	160	20	to	to	PART
fnp-3453	160	21	figure	figure	VERB
fnp-3453	160	22	3	3	NUM
fnp-3453	160	23	.	.	PUNCT
fnp-3453	161	1	a	a	DET
fnp-3453	161	2	heatmap	heatmap	NOUN
fnp-3453	161	3	was	be	AUX
fnp-3453	161	4	then	then	ADV
fnp-3453	161	5	created	create	VERB
fnp-3453	161	6	using	use	VERB
fnp-3453	161	7	processes	process	NOUN
fnp-3453	161	8	that	that	PRON
fnp-3453	161	9	were	be	AUX
fnp-3453	161	10	significantly	significantly	ADV
fnp-3453	161	11	enriched	enrich	VERB
fnp-3453	161	12	in	in	ADP
fnp-3453	161	13	at	at	ADV
fnp-3453	161	14	least	least	ADV
fnp-3453	161	15	one	one	NUM
fnp-3453	161	16	category	category	NOUN
fnp-3453	161	17	(	(	PUNCT
fnp-3453	161	18	figure	figure	NOUN
fnp-3453	161	19	5	5	NUM
fnp-3453	161	20	)	)	PUNCT
fnp-3453	161	21	.	.	PUNCT
fnp-3453	162	1	the	the	DET
fnp-3453	162	2	immune	immune	ADJ
fnp-3453	162	3	category	category	NOUN
fnp-3453	162	4	had	have	VERB
fnp-3453	162	5	51	51	NUM
fnp-3453	162	6	(	(	PUNCT
fnp-3453	162	7	13.7	13.7	NUM
fnp-3453	162	8	%	%	NOUN
fnp-3453	162	9	)	)	PUNCT
fnp-3453	162	10	processes	process	NOUN
fnp-3453	162	11	.	.	PUNCT
fnp-3453	163	1	the	the	DET
fnp-3453	163	2	majority	majority	NOUN
fnp-3453	163	3	of	of	ADP
fnp-3453	163	4	processes	process	NOUN
fnp-3453	163	5	were	be	AUX
fnp-3453	163	6	observed	observe	VERB
fnp-3453	163	7	to	to	PART
fnp-3453	163	8	be	be	AUX
fnp-3453	163	9	elevated	elevate	VERB
fnp-3453	163	10	in	in	ADP
fnp-3453	163	11	the	the	DET
fnp-3453	163	12	sulcus	sulcus	NOUN
fnp-3453	163	13	compared	compare	VERB
fnp-3453	163	14	to	to	ADP
fnp-3453	163	15	the	the	DET
fnp-3453	163	16	crest	crest	NOUN
fnp-3453	163	17	across	across	ADP
fnp-3453	163	18	all	all	DET
fnp-3453	163	19	3	3	NUM
fnp-3453	163	20	sample	sample	NOUN
fnp-3453	163	21	groups	group	NOUN
fnp-3453	163	22	.	.	PUNCT
fnp-3453	164	1	however	however	ADV
fnp-3453	164	2	,	,	PUNCT
fnp-3453	164	3	among	among	ADP
fnp-3453	164	4	the	the	DET
fnp-3453	164	5	cte	cte	PROPN
fnp-3453	164	6	group	group	NOUN
fnp-3453	164	7	there	there	PRON
fnp-3453	164	8	was	be	VERB
fnp-3453	164	9	an	an	DET
fnp-3453	164	10	increase	increase	NOUN
fnp-3453	164	11	in	in	ADP
fnp-3453	164	12	the	the	DET
fnp-3453	164	13	number	number	NOUN
fnp-3453	164	14	of	of	ADP
fnp-3453	164	15	processes	process	NOUN
fnp-3453	164	16	that	that	PRON
fnp-3453	164	17	had	have	VERB
fnp-3453	164	18	a	a	DET
fnp-3453	164	19	negative	negative	ADJ
fnp-3453	164	20	enrichment	enrichment	NOUN
fnp-3453	164	21	in	in	ADP
fnp-3453	164	22	the	the	DET
fnp-3453	164	23	sulcus	sulcus	NOUN
fnp-3453	164	24	compare	compare	VERB
fnp-3453	164	25	to	to	ADP
fnp-3453	164	26	the	the	DET
fnp-3453	164	27	crest	crest	NOUN
fnp-3453	164	28	(	(	PUNCT
fnp-3453	164	29	figure	figure	NOUN
fnp-3453	164	30	5a	5a	NUM
fnp-3453	164	31	)	)	PUNCT
fnp-3453	164	32	.	.	PUNCT
fnp-3453	165	1	next	next	ADV
fnp-3453	165	2	,	,	PUNCT
fnp-3453	165	3	there	there	PRON
fnp-3453	165	4	were	be	VERB
fnp-3453	165	5	30	30	NUM
fnp-3453	165	6	(	(	PUNCT
fnp-3453	165	7	8.0	8.0	NUM
fnp-3453	165	8	%	%	NOUN
fnp-3453	165	9	)	)	PUNCT
fnp-3453	165	10	transcription	transcription	NOUN
fnp-3453	165	11	/	/	SYM
fnp-3453	165	12	translation	translation	NOUN
fnp-3453	165	13	processes	process	NOUN
fnp-3453	165	14	,	,	PUNCT
fnp-3453	165	15	the	the	DET
fnp-3453	165	16	majority	majority	NOUN
fnp-3453	165	17	of	of	ADP
fnp-3453	165	18	which	which	PRON
fnp-3453	165	19	were	be	AUX
fnp-3453	165	20	positively	positively	ADV
fnp-3453	165	21	enriched	enrich	VERB
fnp-3453	165	22	in	in	ADP
fnp-3453	165	23	the	the	DET
fnp-3453	165	24	sulcus	sulcus	NOUN
fnp-3453	165	25	compared	compare	VERB
fnp-3453	165	26	to	to	ADP
fnp-3453	165	27	the	the	DET
fnp-3453	165	28	crest	crest	NOUN
fnp-3453	165	29	(	(	PUNCT
fnp-3453	165	30	figure	figure	NOUN
fnp-3453	165	31	5b	5b	NUM
fnp-3453	165	32	)	)	PUNCT
fnp-3453	165	33	.	.	PUNCT
fnp-3453	166	1	the	the	DET
fnp-3453	166	2	category	category	NOUN
fnp-3453	166	3	with	with	ADP
fnp-3453	166	4	the	the	DET
fnp-3453	166	5	most	most	ADV
fnp-3453	166	6	assigned	assign	VERB
fnp-3453	166	7	processes	process	NOUN
fnp-3453	166	8	was	be	AUX
fnp-3453	166	9	the	the	DET
fnp-3453	166	10	neuronal	neuronal	ADJ
fnp-3453	166	11	category	category	NOUN
fnp-3453	166	12	with	with	ADP
fnp-3453	166	13	99	99	NUM
fnp-3453	166	14	(	(	PUNCT
fnp-3453	166	15	26.5	26.5	NUM
fnp-3453	166	16	%	%	NOUN
fnp-3453	166	17	)	)	PUNCT
fnp-3453	166	18	processes	process	NOUN
fnp-3453	166	19	.	.	PUNCT
fnp-3453	167	1	almost	almost	ADV
fnp-3453	167	2	all	all	PRON
fnp-3453	167	3	of	of	ADP
fnp-3453	167	4	the	the	DET
fnp-3453	167	5	neuronal	neuronal	ADJ
fnp-3453	167	6	processes	process	NOUN
fnp-3453	167	7	demonstrated	demonstrate	VERB
fnp-3453	167	8	a	a	DET
fnp-3453	167	9	negative	negative	ADJ
fnp-3453	167	10	enrichment	enrichment	NOUN
fnp-3453	167	11	in	in	ADP
fnp-3453	167	12	the	the	DET
fnp-3453	167	13	sulcus	sulcus	NOUN
fnp-3453	167	14	.	.	PUNCT
fnp-3453	168	1	of	of	ADP
fnp-3453	168	2	the	the	DET
fnp-3453	168	3	few	few	ADJ
fnp-3453	168	4	processes	process	NOUN
fnp-3453	168	5	that	that	PRON
fnp-3453	168	6	did	do	AUX
fnp-3453	168	7	have	have	VERB
fnp-3453	168	8	a	a	DET
fnp-3453	168	9	positive	positive	ADJ
fnp-3453	168	10	enrichment	enrichment	NOUN
fnp-3453	168	11	,	,	PUNCT
fnp-3453	168	12	there	there	PRON
fnp-3453	168	13	was	be	VERB
fnp-3453	168	14	a	a	DET
fnp-3453	168	15	trend	trend	NOUN
fnp-3453	168	16	towards	towards	ADP
fnp-3453	168	17	decreasing	decrease	VERB
fnp-3453	168	18	after	after	ADP
fnp-3453	168	19	rhi	rhi	PROPN
fnp-3453	168	20	and	and	CCONJ
fnp-3453	168	21	during	during	ADP
fnp-3453	168	22	cte	cte	PROPN
fnp-3453	168	23	(	(	PUNCT
fnp-3453	168	24	figure	figure	NOUN
fnp-3453	168	25	4c	4c	NOUN
fnp-3453	168	26	)	)	PUNCT
fnp-3453	168	27	.	.	PUNCT
fnp-3453	169	1	next	next	ADV
fnp-3453	169	2	,	,	PUNCT
fnp-3453	169	3	there	there	PRON
fnp-3453	169	4	were	be	VERB
fnp-3453	169	5	9	9	NUM
fnp-3453	169	6	(	(	PUNCT
fnp-3453	169	7	2.4	2.4	NUM
fnp-3453	169	8	%	%	NOUN
fnp-3453	169	9	)	)	PUNCT
fnp-3453	169	10	cytoskeletal	cytoskeletal	ADJ
fnp-3453	169	11	processes	process	NOUN
fnp-3453	169	12	.	.	PUNCT
fnp-3453	170	1	the	the	DET
fnp-3453	170	2	ecm	ecm	PROPN
fnp-3453	170	3	category	category	NOUN
fnp-3453	170	4	had	have	VERB
fnp-3453	170	5	34	34	NUM
fnp-3453	170	6	(	(	PUNCT
fnp-3453	170	7	6.4	6.4	NUM
fnp-3453	170	8	%	%	NOUN
fnp-3453	170	9	)	)	PUNCT
fnp-3453	170	10	processes	process	NOUN
fnp-3453	170	11	.	.	PUNCT
fnp-3453	171	1	all	all	DET
fnp-3453	171	2	the	the	DET
fnp-3453	171	3	processes	process	NOUN
fnp-3453	171	4	were	be	AUX
fnp-3453	171	5	positively	positively	ADV
fnp-3453	171	6	enriched	enrich	VERB
fnp-3453	171	7	in	in	ADP
fnp-3453	171	8	control	control	NOUN
fnp-3453	171	9	cases	case	NOUN
fnp-3453	171	10	.	.	PUNCT
fnp-3453	172	1	however	however	ADV
fnp-3453	172	2	,	,	PUNCT
fnp-3453	172	3	there	there	PRON
fnp-3453	172	4	was	be	VERB
fnp-3453	172	5	a	a	DET
fnp-3453	172	6	possible	possible	ADJ
fnp-3453	172	7	progressive	progressive	ADJ
fnp-3453	172	8	increase	increase	NOUN
fnp-3453	172	9	in	in	ADP
fnp-3453	172	10	negatively	negatively	ADV
fnp-3453	172	11	enriched	enrich	VERB
fnp-3453	172	12	processes	process	NOUN
fnp-3453	172	13	through	through	ADP
fnp-3453	172	14	rhi	rhi	PROPN
fnp-3453	172	15	and	and	CCONJ
fnp-3453	172	16	cte	cte	PROPN
fnp-3453	172	17	(	(	PUNCT
fnp-3453	172	18	figure	figure	NOUN
fnp-3453	172	19	5e	5e	NUM
fnp-3453	172	20	)	)	PUNCT
fnp-3453	172	21	.	.	PUNCT
fnp-3453	173	1	mitochondria	mitochondria	PROPN
fnp-3453	173	2	had	have	VERB
fnp-3453	173	3	24	24	NUM
fnp-3453	173	4	(	(	PUNCT
fnp-3453	173	5	6.4	6.4	NUM
fnp-3453	173	6	%	%	NOUN
fnp-3453	173	7	)	)	PUNCT
fnp-3453	173	8	associated	associate	VERB
fnp-3453	173	9	processes	process	NOUN
fnp-3453	173	10	.	.	PUNCT
fnp-3453	174	1	the	the	DET
fnp-3453	174	2	rhi	rhi	PROPN
fnp-3453	174	3	group	group	NOUN
fnp-3453	174	4	only	only	ADV
fnp-3453	174	5	had	have	VERB
fnp-3453	174	6	1	1	NUM
fnp-3453	174	7	negatively	negatively	ADV
fnp-3453	174	8	enriched	enrich	VERB
fnp-3453	174	9	pathway	pathway	NOUN
fnp-3453	174	10	while	while	SCONJ
fnp-3453	174	11	control	control	NOUN
fnp-3453	174	12	and	and	CCONJ
fnp-3453	174	13	cte	cte	NOUN
fnp-3453	174	14	had	have	VERB
fnp-3453	174	15	a	a	DET
fnp-3453	174	16	mixed	mixed	ADJ
fnp-3453	174	17	split	split	NOUN
fnp-3453	174	18	of	of	ADP
fnp-3453	174	19	positive	positive	ADJ
fnp-3453	174	20	and	and	CCONJ
fnp-3453	174	21	negative	negative	ADJ
fnp-3453	174	22	processes	process	NOUN
fnp-3453	174	23	(	(	PUNCT
fnp-3453	174	24	figure	figure	NOUN
fnp-3453	174	25	5f	5f	NOUN
fnp-3453	174	26	)	)	PUNCT
fnp-3453	174	27	.	.	PUNCT
fnp-3453	175	1	the	the	DET
fnp-3453	175	2	signaling	signal	VERB
fnp-3453	175	3	category	category	NOUN
fnp-3453	175	4	had	have	VERB
fnp-3453	175	5	56	56	NUM
fnp-3453	175	6	(	(	PUNCT
fnp-3453	175	7	15.0	15.0	NUM
fnp-3453	175	8	%	%	NOUN
fnp-3453	175	9	)	)	PUNCT
fnp-3453	175	10	processes	process	NOUN
fnp-3453	175	11	and	and	CCONJ
fnp-3453	175	12	was	be	AUX
fnp-3453	175	13	evenly	evenly	ADV
fnp-3453	175	14	split	split	VERB
fnp-3453	175	15	between	between	ADP
fnp-3453	175	16	positive	positive	ADJ
fnp-3453	175	17	and	and	CCONJ
fnp-3453	175	18	negative	negative	ADJ
fnp-3453	175	19	enrichment	enrichment	NOUN
fnp-3453	175	20	(	(	PUNCT
fnp-3453	175	21	figure	figure	NOUN
fnp-3453	175	22	5	5	NUM
fnp-3453	175	23	g	g	NOUN
fnp-3453	175	24	)	)	PUNCT
fnp-3453	175	25	.	.	PUNCT
fnp-3453	176	1	the	the	DET
fnp-3453	176	2	vascular	vascular	ADJ
fnp-3453	176	3	category	category	NOUN
fnp-3453	176	4	had	have	VERB
fnp-3453	176	5	14	14	NUM
fnp-3453	176	6	(	(	PUNCT
fnp-3453	176	7	8.0	8.0	NUM
fnp-3453	176	8	%	%	NOUN
fnp-3453	176	9	)	)	PUNCT
fnp-3453	176	10	processes	process	NOUN
fnp-3453	176	11	.	.	PUNCT
fnp-3453	177	1	the	the	DET
fnp-3453	177	2	control	control	NOUN
fnp-3453	177	3	group	group	NOUN
fnp-3453	177	4	was	be	AUX
fnp-3453	177	5	entirely	entirely	ADV
fnp-3453	177	6	positively	positively	ADV
fnp-3453	177	7	enriched	enrich	VERB
fnp-3453	177	8	in	in	ADP
fnp-3453	177	9	the	the	DET
fnp-3453	177	10	sulcus	sulcus	NOUN
fnp-3453	177	11	but	but	CCONJ
fnp-3453	177	12	there	there	PRON
fnp-3453	177	13	was	be	VERB
fnp-3453	177	14	a	a	DET
fnp-3453	177	15	switch	switch	NOUN
fnp-3453	177	16	to	to	PART
fnp-3453	177	17	more	more	ADV
fnp-3453	177	18	negatively	negatively	ADV
fnp-3453	177	19	associated	associate	VERB
fnp-3453	177	20	processes	process	NOUN
fnp-3453	177	21	in	in	ADP
fnp-3453	177	22	rhi	rhi	PROPN
fnp-3453	177	23	and	and	CCONJ
fnp-3453	177	24	cte	cte	PROPN
fnp-3453	177	25	(	(	PUNCT
fnp-3453	177	26	figure	figure	NOUN
fnp-3453	177	27	5h	5h	NUM
fnp-3453	177	28	)	)	PUNCT
fnp-3453	177	29	.	.	PUNCT
fnp-3453	178	1	the	the	DET
fnp-3453	178	2	endocytosis	endocytosis	NOUN
fnp-3453	178	3	/	/	SYM
fnp-3453	178	4	exocytosis	exocytosis	NOUN
fnp-3453	178	5	category	category	NOUN
fnp-3453	178	6	had	have	VERB
fnp-3453	178	7	13	13	NUM
fnp-3453	178	8	(	(	PUNCT
fnp-3453	178	9	3.5	3.5	NUM
fnp-3453	178	10	%	%	NOUN
fnp-3453	178	11	)	)	PUNCT
fnp-3453	178	12	processes	process	NOUN
fnp-3453	178	13	and	and	CCONJ
fnp-3453	178	14	was	be	AUX
fnp-3453	178	15	primarily	primarily	ADV
fnp-3453	178	16	negatively	negatively	ADV
fnp-3453	178	17	enriched	enrich	VERB
fnp-3453	178	18	in	in	ADP
fnp-3453	178	19	the	the	DET
fnp-3453	178	20	sulcus	sulcus	NOUN
fnp-3453	178	21	(	(	PUNCT
fnp-3453	178	22	figure	figure	NOUN
fnp-3453	178	23	5i	5i	NUM
fnp-3453	178	24	)	)	PUNCT
fnp-3453	178	25	.	.	PUNCT
fnp-3453	179	1	the	the	DET
fnp-3453	179	2	protein	protein	NOUN
fnp-3453	179	3	processing	processing	NOUN
fnp-3453	179	4	category	category	NOUN
fnp-3453	179	5	had	have	VERB
fnp-3453	179	6	16	16	NUM
fnp-3453	179	7	(	(	PUNCT
fnp-3453	179	8	4.3	4.3	NUM
fnp-3453	179	9	%	%	NOUN
fnp-3453	179	10	)	)	PUNCT
fnp-3453	179	11	processes	process	NOUN
fnp-3453	179	12	and	and	CCONJ
fnp-3453	179	13	was	be	AUX
fnp-3453	179	14	a	a	DET
fnp-3453	179	15	mix	mix	NOUN
fnp-3453	179	16	of	of	ADP
fnp-3453	179	17	positive	positive	ADJ
fnp-3453	179	18	and	and	CCONJ
fnp-3453	179	19	negative	negative	ADJ
fnp-3453	179	20	processes	process	NOUN
fnp-3453	179	21	.	.	PUNCT
fnp-3453	180	1	there	there	PRON
fnp-3453	180	2	appeared	appear	VERB
fnp-3453	180	3	to	to	PART
fnp-3453	180	4	be	be	AUX
fnp-3453	180	5	an	an	DET
fnp-3453	180	6	increase	increase	NOUN
fnp-3453	180	7	in	in	ADP
fnp-3453	180	8	negative	negative	ADJ
fnp-3453	180	9	processes	process	NOUN
fnp-3453	180	10	associated	associate	VERB
fnp-3453	180	11	with	with	ADP
fnp-3453	180	12	cte	cte	PROPN
fnp-3453	180	13	(	(	PUNCT
fnp-3453	180	14	figure	figure	NOUN
fnp-3453	180	15	5j	5j	NUM
fnp-3453	180	16	)	)	PUNCT
fnp-3453	180	17	.	.	PUNCT
fnp-3453	181	1	finally	finally	ADV
fnp-3453	181	2	,	,	PUNCT
fnp-3453	181	3	the	the	DET
fnp-3453	181	4	27	27	NUM
fnp-3453	181	5	processes	process	NOUN
fnp-3453	181	6	that	that	PRON
fnp-3453	181	7	did	do	AUX
fnp-3453	181	8	not	not	PART
fnp-3453	181	9	fit	fit	VERB
fnp-3453	181	10	into	into	ADP
fnp-3453	181	11	the	the	DET
fnp-3453	181	12	previous	previous	ADJ
fnp-3453	181	13	10	10	NUM
fnp-3453	181	14	categories	category	NOUN
fnp-3453	181	15	were	be	AUX
fnp-3453	181	16	placed	place	VERB
fnp-3453	181	17	into	into	ADP
fnp-3453	181	18	“	"	PUNCT
fnp-3453	181	19	other	other	ADJ
fnp-3453	181	20	”	"	PUNCT
fnp-3453	181	21	(	(	PUNCT
fnp-3453	181	22	figure	figure	NOUN
fnp-3453	181	23	5k	5k	NUM
fnp-3453	181	24	)	)	PUNCT
fnp-3453	181	25	.	.	PUNCT
fnp-3453	182	1	overall	overall	ADJ
fnp-3453	182	2	,	,	PUNCT
fnp-3453	182	3	throughout	throughout	ADP
fnp-3453	182	4	all	all	DET
fnp-3453	182	5	11	11	NUM
fnp-3453	182	6	categories	category	NOUN
fnp-3453	182	7	,	,	PUNCT
fnp-3453	182	8	there	there	PRON
fnp-3453	182	9	was	be	VERB
fnp-3453	182	10	a	a	DET
fnp-3453	182	11	high	high	ADJ
fnp-3453	182	12	agreement	agreement	NOUN
fnp-3453	182	13	in	in	ADP
fnp-3453	182	14	the	the	DET
fnp-3453	182	15	direction	direction	NOUN
fnp-3453	182	16	of	of	ADP
fnp-3453	182	17	effect	effect	NOUN
fnp-3453	182	18	in	in	ADP
fnp-3453	182	19	all	all	DET
fnp-3453	182	20	cases	case	NOUN
fnp-3453	182	21	.	.	PUNCT
fnp-3453	183	1	73	73	NUM
fnp-3453	183	2	(	(	PUNCT
fnp-3453	183	3	21.2	21.2	NUM
fnp-3453	183	4	%	%	NOUN
fnp-3453	183	5	)	)	PUNCT
fnp-3453	183	6	processes	process	NOUN
fnp-3453	183	7	did	do	AUX
fnp-3453	183	8	not	not	PART
fnp-3453	183	9	have	have	VERB
fnp-3453	183	10	the	the	DET
fnp-3453	183	11	same	same	ADJ
fnp-3453	183	12	direction	direction	NOUN
fnp-3453	183	13	of	of	ADP
fnp-3453	183	14	effect	effect	NOUN
fnp-3453	183	15	.	.	PUNCT
fnp-3453	184	1	figure	figure	VERB
fnp-3453	184	2	5	5	NUM
fnp-3453	184	3	.	.	PUNCT
fnp-3453	184	4	heatmap	heatmap	NOUN
fnp-3453	184	5	of	of	ADP
fnp-3453	184	6	sulcal	sulcal	ADJ
fnp-3453	184	7	specific	specific	ADJ
fnp-3453	184	8	gsea	gsea	NOUN
fnp-3453	184	9	biological	biological	ADJ
fnp-3453	184	10	processesusing	processesuse	VERB
fnp-3453	184	11	the	the	DET
fnp-3453	184	12	genes	gene	NOUN
fnp-3453	184	13	that	that	PRON
fnp-3453	184	14	were	be	AUX
fnp-3453	184	15	significantly	significantly	ADV
fnp-3453	184	16	altered	alter	VERB
fnp-3453	184	17	in	in	ADP
fnp-3453	184	18	the	the	DET
fnp-3453	184	19	sulcus	sulcus	NOUN
fnp-3453	184	20	compared	compare	VERB
fnp-3453	184	21	to	to	ADP
fnp-3453	184	22	the	the	DET
fnp-3453	184	23	crest	crest	NOUN
fnp-3453	184	24	,	,	PUNCT
fnp-3453	184	25	we	we	PRON
fnp-3453	184	26	used	use	VERB
fnp-3453	184	27	gsea	gsea	NOUN
fnp-3453	184	28	to	to	PART
fnp-3453	184	29	identify	identify	VERB
fnp-3453	184	30	biological	biological	ADJ
fnp-3453	184	31	processes	process	NOUN
fnp-3453	184	32	.	.	PUNCT
fnp-3453	185	1	each	each	DET
fnp-3453	185	2	process	process	NOUN
fnp-3453	185	3	was	be	AUX
fnp-3453	185	4	then	then	ADV
fnp-3453	185	5	assigned	assign	VERB
fnp-3453	185	6	to	to	ADP
fnp-3453	185	7	a	a	DET
fnp-3453	185	8	greater	great	ADJ
fnp-3453	185	9	overall	overall	ADJ
fnp-3453	185	10	biological	biological	ADJ
fnp-3453	185	11	category	category	NOUN
fnp-3453	185	12	:	:	PUNCT
fnp-3453	185	13	a	a	X
fnp-3453	185	14	)	)	PUNCT
fnp-3453	185	15	immune	immune	ADJ
fnp-3453	185	16	,	,	PUNCT
fnp-3453	185	17	b	b	NOUN
fnp-3453	185	18	)	)	PUNCT
fnp-3453	185	19	transcriptional	transcriptional	ADJ
fnp-3453	185	20	/	/	SYM
fnp-3453	185	21	translational	translational	ADJ
fnp-3453	185	22	,	,	PUNCT
fnp-3453	185	23	c	c	NOUN
fnp-3453	185	24	)	)	PUNCT
fnp-3453	185	25	neuronal	neuronal	ADJ
fnp-3453	185	26	,	,	PUNCT
fnp-3453	185	27	d	d	NOUN
fnp-3453	185	28	)	)	PUNCT
fnp-3453	185	29	cytoskeletal	cytoskeletal	NOUN
fnp-3453	185	30	,	,	PUNCT
fnp-3453	185	31	e	e	NOUN
fnp-3453	185	32	)	)	PUNCT
fnp-3453	185	33	extracellular	extracellular	ADJ
fnp-3453	185	34	matrix	matrix	NOUN
fnp-3453	185	35	,	,	PUNCT
fnp-3453	185	36	f	f	X
fnp-3453	185	37	)	)	PUNCT
fnp-3453	185	38	mitochondria	mitochondria	NOUN
fnp-3453	185	39	/	/	SYM
fnp-3453	185	40	metabolism	metabolism	NOUN
fnp-3453	185	41	,	,	PUNCT
fnp-3453	185	42	g	g	NOUN
fnp-3453	185	43	)	)	PUNCT
fnp-3453	185	44	signaling	signal	VERB
fnp-3453	185	45	,	,	PUNCT
fnp-3453	185	46	h	h	NOUN
fnp-3453	185	47	)	)	PUNCT
fnp-3453	185	48	vascular	vascular	NOUN
fnp-3453	185	49	,	,	PUNCT
fnp-3453	185	50	i	i	NOUN
fnp-3453	185	51	)	)	PUNCT
fnp-3453	185	52	endocytosis	endocytosis	NOUN
fnp-3453	185	53	/	/	SYM
fnp-3453	185	54	exocytosis	exocytosis	NOUN
fnp-3453	185	55	,	,	PUNCT
fnp-3453	185	56	j	j	NOUN
fnp-3453	185	57	)	)	PUNCT
fnp-3453	185	58	protein	protein	NOUN
fnp-3453	185	59	processing	processing	NOUN
fnp-3453	185	60	,	,	PUNCT
fnp-3453	185	61	k	k	NOUN
fnp-3453	185	62	)	)	PUNCT
fnp-3453	185	63	other	other	ADJ
fnp-3453	185	64	.	.	PUNCT
fnp-3453	186	1	[	[	AUX
fnp-3453	186	2	please	please	INTJ
fnp-3453	186	3	click	click	VERB
fnp-3453	186	4	on	on	ADP
fnp-3453	186	5	the	the	DET
fnp-3453	186	6	figure	figure	NOUN
fnp-3453	186	7	to	to	PART
fnp-3453	186	8	download	download	VERB
fnp-3453	186	9	a	a	DET
fnp-3453	186	10	high	high	ADJ
fnp-3453	186	11	-	-	PUNCT
fnp-3453	186	12	resolution	resolution	NOUN
fnp-3453	186	13	version	version	NOUN
fnp-3453	186	14	]	]	PUNCT
fnp-3453	186	15	next	next	ADV
fnp-3453	186	16	,	,	PUNCT
fnp-3453	186	17	using	use	VERB
fnp-3453	186	18	the	the	DET
fnp-3453	186	19	ratio	ratio	NOUN
fnp-3453	186	20	that	that	PRON
fnp-3453	186	21	was	be	AUX
fnp-3453	186	22	created	create	VERB
fnp-3453	186	23	by	by	ADP
fnp-3453	186	24	directly	directly	ADV
fnp-3453	186	25	comparing	compare	VERB
fnp-3453	186	26	the	the	DET
fnp-3453	186	27	differentially	differentially	ADV
fnp-3453	186	28	expressed	express	VERB
fnp-3453	186	29	genes	gene	NOUN
fnp-3453	186	30	in	in	ADP
fnp-3453	186	31	the	the	DET
fnp-3453	186	32	sulcus	sulcus	NOUN
fnp-3453	186	33	to	to	ADP
fnp-3453	186	34	crest	crest	NOUN
fnp-3453	186	35	within	within	ADP
fnp-3453	186	36	each	each	DET
fnp-3453	186	37	group	group	NOUN
fnp-3453	186	38	,	,	PUNCT
fnp-3453	186	39	we	we	PRON
fnp-3453	186	40	compared	compare	VERB
fnp-3453	186	41	how	how	SCONJ
fnp-3453	186	42	those	those	DET
fnp-3453	186	43	ratios	ratio	NOUN
fnp-3453	186	44	changed	change	VERB
fnp-3453	186	45	in	in	ADP
fnp-3453	186	46	rhi	rhi	PROPN
fnp-3453	186	47	and	and	CCONJ
fnp-3453	186	48	cte	cte	PROPN
fnp-3453	186	49	relative	relative	ADJ
fnp-3453	186	50	to	to	ADP
fnp-3453	186	51	control	control	NOUN
fnp-3453	186	52	(	(	PUNCT
fnp-3453	186	53	figure	figure	NOUN
fnp-3453	186	54	1c	1c	NOUN
fnp-3453	186	55	,	,	PUNCT
fnp-3453	186	56	comparison	comparison	NOUN
fnp-3453	186	57	3	3	NUM
fnp-3453	186	58	)	)	PUNCT
fnp-3453	186	59	.	.	PUNCT
fnp-3453	187	1	this	this	DET
fnp-3453	187	2	analysis	analysis	NOUN
fnp-3453	187	3	provided	provide	VERB
fnp-3453	187	4	additional	additional	ADJ
fnp-3453	187	5	information	information	NOUN
fnp-3453	187	6	into	into	ADP
fnp-3453	187	7	how	how	SCONJ
fnp-3453	187	8	genes	gene	NOUN
fnp-3453	187	9	which	which	PRON
fnp-3453	187	10	were	be	AUX
fnp-3453	187	11	increased	increase	VERB
fnp-3453	187	12	in	in	ADP
fnp-3453	187	13	the	the	DET
fnp-3453	187	14	sulcus	sulcus	NOUN
fnp-3453	187	15	compared	compare	VERB
fnp-3453	187	16	to	to	ADP
fnp-3453	187	17	the	the	DET
fnp-3453	187	18	crest	crest	NOUN
fnp-3453	187	19	change	change	NOUN
fnp-3453	187	20	after	after	ADP
fnp-3453	187	21	exposure	exposure	NOUN
fnp-3453	187	22	to	to	PART
fnp-3453	187	23	head	head	VERB
fnp-3453	187	24	trauma	trauma	NOUN
fnp-3453	187	25	and	and	CCONJ
fnp-3453	187	26	p	p	X
fnp-3453	187	27	-	-	PUNCT
fnp-3453	187	28	tau	tau	PROPN
fnp-3453	187	29	pathology	pathology	NOUN
fnp-3453	187	30	.	.	PUNCT
fnp-3453	188	1	87	87	NUM
fnp-3453	188	2	processes	process	NOUN
fnp-3453	188	3	were	be	AUX
fnp-3453	188	4	found	find	VERB
fnp-3453	188	5	to	to	PART
fnp-3453	188	6	be	be	AUX
fnp-3453	188	7	significantly	significantly	ADV
fnp-3453	188	8	altered	alter	VERB
fnp-3453	188	9	in	in	ADP
fnp-3453	188	10	rhi	rhi	PROPN
fnp-3453	188	11	vs	vs	ADP
fnp-3453	188	12	control	control	NOUN
fnp-3453	188	13	,	,	PUNCT
fnp-3453	188	14	and	and	CCONJ
fnp-3453	188	15	127	127	NUM
fnp-3453	188	16	processes	process	NOUN
fnp-3453	188	17	were	be	AUX
fnp-3453	188	18	altered	alter	VERB
fnp-3453	188	19	in	in	ADP
fnp-3453	188	20	cte	cte	PROPN
fnp-3453	188	21	vs	vs	ADP
fnp-3453	188	22	control	control	NOUN
fnp-3453	188	23	.	.	PUNCT
fnp-3453	189	1	the	the	DET
fnp-3453	189	2	same	same	ADJ
fnp-3453	189	3	11	11	NUM
fnp-3453	189	4	greater	great	ADJ
fnp-3453	189	5	biological	biological	ADJ
fnp-3453	189	6	processes	process	NOUN
fnp-3453	189	7	were	be	AUX
fnp-3453	189	8	used	use	VERB
fnp-3453	189	9	to	to	ADP
fnp-3453	189	10	group	group	NOUN
fnp-3453	189	11	gsea	gsea	NOUN
fnp-3453	189	12	processes	process	NOUN
fnp-3453	189	13	and	and	CCONJ
fnp-3453	189	14	all	all	DET
fnp-3453	189	15	processes	process	NOUN
fnp-3453	189	16	that	that	PRON
fnp-3453	189	17	were	be	AUX
fnp-3453	189	18	significant	significant	ADJ
fnp-3453	189	19	for	for	ADP
fnp-3453	189	20	at	at	ADV
fnp-3453	189	21	least	least	ADJ
fnp-3453	189	22	one	one	NUM
fnp-3453	189	23	of	of	ADP
fnp-3453	189	24	the	the	DET
fnp-3453	189	25	two	two	NUM
fnp-3453	189	26	comparisons	comparison	NOUN
fnp-3453	189	27	were	be	AUX
fnp-3453	189	28	included	include	VERB
fnp-3453	189	29	in	in	ADP
fnp-3453	189	30	a	a	DET
fnp-3453	189	31	heatmap	heatmap	NOUN
fnp-3453	189	32	(	(	PUNCT
fnp-3453	189	33	figure	figure	VERB
fnp-3453	189	34	6a	6a	NOUN
fnp-3453	189	35	-	-	PUNCT
fnp-3453	189	36	k	k	NOUN
fnp-3453	189	37	)	)	PUNCT
fnp-3453	189	38	.	.	PUNCT
fnp-3453	190	1	there	there	PRON
fnp-3453	190	2	were	be	VERB
fnp-3453	190	3	54	54	NUM
fnp-3453	190	4	immune	immune	ADJ
fnp-3453	190	5	processes	process	NOUN
fnp-3453	190	6	altered	alter	VERB
fnp-3453	190	7	(	(	PUNCT
fnp-3453	190	8	figure	figure	NOUN
fnp-3453	190	9	6a	6a	NOUN
fnp-3453	190	10	)	)	PUNCT
fnp-3453	190	11	.	.	PUNCT
fnp-3453	191	1	this	this	PRON
fnp-3453	191	2	was	be	AUX
fnp-3453	191	3	the	the	DET
fnp-3453	191	4	largest	large	ADJ
fnp-3453	191	5	number	number	NOUN
fnp-3453	191	6	of	of	ADP
fnp-3453	191	7	altered	alter	VERB
fnp-3453	191	8	processes	process	NOUN
fnp-3453	191	9	compared	compare	VERB
fnp-3453	191	10	to	to	ADP
fnp-3453	191	11	the	the	DET
fnp-3453	191	12	other	other	ADJ
fnp-3453	191	13	10	10	NUM
fnp-3453	191	14	categories	category	NOUN
fnp-3453	191	15	.	.	PUNCT
fnp-3453	192	1	the	the	DET
fnp-3453	192	2	majority	majority	NOUN
fnp-3453	192	3	of	of	ADP
fnp-3453	192	4	immune	immune	ADJ
fnp-3453	192	5	processes	process	NOUN
fnp-3453	192	6	were	be	AUX
fnp-3453	192	7	observed	observe	VERB
fnp-3453	192	8	to	to	PART
fnp-3453	192	9	be	be	AUX
fnp-3453	192	10	decreased	decrease	VERB
fnp-3453	192	11	compared	compare	VERB
fnp-3453	192	12	to	to	ADP
fnp-3453	192	13	controls	control	NOUN
fnp-3453	192	14	.	.	PUNCT
fnp-3453	193	1	transcription	transcription	NOUN
fnp-3453	193	2	/	/	SYM
fnp-3453	193	3	translation	translation	NOUN
fnp-3453	193	4	was	be	AUX
fnp-3453	193	5	the	the	DET
fnp-3453	193	6	second	second	ADV
fnp-3453	193	7	largest	large	ADJ
fnp-3453	193	8	with	with	SCONJ
fnp-3453	193	9	46	46	NUM
fnp-3453	193	10	processes	process	NOUN
fnp-3453	193	11	being	be	AUX
fnp-3453	193	12	altered	alter	VERB
fnp-3453	193	13	(	(	PUNCT
fnp-3453	193	14	figure	figure	NOUN
fnp-3453	193	15	6b	6b	NUM
fnp-3453	193	16	)	)	PUNCT
fnp-3453	193	17	.	.	PUNCT
fnp-3453	194	1	the	the	DET
fnp-3453	194	2	neuronal	neuronal	ADJ
fnp-3453	194	3	category	category	NOUN
fnp-3453	194	4	had	have	VERB
fnp-3453	194	5	31	31	NUM
fnp-3453	194	6	processes	process	NOUN
fnp-3453	194	7	and	and	CCONJ
fnp-3453	194	8	the	the	DET
fnp-3453	194	9	majority	majority	NOUN
fnp-3453	194	10	were	be	AUX
fnp-3453	194	11	observed	observe	VERB
fnp-3453	194	12	to	to	PART
fnp-3453	194	13	be	be	AUX
fnp-3453	194	14	increased	increase	VERB
fnp-3453	194	15	compared	compare	VERB
fnp-3453	194	16	to	to	ADP
fnp-3453	194	17	control	control	NOUN
fnp-3453	194	18	(	(	PUNCT
fnp-3453	194	19	figure	figure	NOUN
fnp-3453	194	20	6c	6c	PROPN
fnp-3453	194	21	)	)	PUNCT
fnp-3453	194	22	.	.	PUNCT
fnp-3453	195	1	cytoskeletal	cytoskeletal	PROPN
fnp-3453	195	2	had	have	VERB
fnp-3453	195	3	16	16	NUM
fnp-3453	195	4	processes	process	NOUN
fnp-3453	195	5	and	and	CCONJ
fnp-3453	195	6	had	have	VERB
fnp-3453	195	7	more	more	ADJ
fnp-3453	195	8	processes	process	NOUN
fnp-3453	195	9	that	that	PRON
fnp-3453	195	10	decreased	decrease	VERB
fnp-3453	195	11	compared	compare	VERB
fnp-3453	195	12	to	to	ADP
fnp-3453	195	13	increased	increase	VERB
fnp-3453	195	14	(	(	PUNCT
fnp-3453	195	15	figure	figure	NOUN
fnp-3453	195	16	6d	6d	NUM
fnp-3453	195	17	)	)	PUNCT
fnp-3453	195	18	.	.	PUNCT
fnp-3453	196	1	ecm	ecm	NOUN
fnp-3453	196	2	had	have	VERB
fnp-3453	196	3	25	25	NUM
fnp-3453	196	4	processes	process	NOUN
fnp-3453	196	5	and	and	CCONJ
fnp-3453	196	6	all	all	PRON
fnp-3453	196	7	of	of	ADP
fnp-3453	196	8	them	they	PRON
fnp-3453	196	9	were	be	AUX
fnp-3453	196	10	decreased	decrease	VERB
fnp-3453	196	11	compared	compare	VERB
fnp-3453	196	12	to	to	ADP
fnp-3453	196	13	control	control	NOUN
fnp-3453	196	14	(	(	PUNCT
fnp-3453	196	15	figure	figure	NOUN
fnp-3453	196	16	6e	6e	NUM
fnp-3453	196	17	)	)	PUNCT
fnp-3453	196	18	.	.	PUNCT
fnp-3453	197	1	mitochondria	mitochondria	PROPN
fnp-3453	197	2	had	have	VERB
fnp-3453	197	3	21	21	NUM
fnp-3453	197	4	processes	process	NOUN
fnp-3453	197	5	and	and	CCONJ
fnp-3453	197	6	the	the	DET
fnp-3453	197	7	majority	majority	NOUN
fnp-3453	197	8	were	be	AUX
fnp-3453	197	9	increased	increase	VERB
fnp-3453	197	10	compared	compare	VERB
fnp-3453	197	11	to	to	ADP
fnp-3453	197	12	controls	control	NOUN
fnp-3453	197	13	(	(	PUNCT
fnp-3453	197	14	figure	figure	NOUN
fnp-3453	197	15	6f	6f	NUM
fnp-3453	197	16	)	)	PUNCT
fnp-3453	197	17	.	.	PUNCT
fnp-3453	198	1	signaling	signal	VERB
fnp-3453	198	2	had	have	VERB
fnp-3453	198	3	44	44	NUM
fnp-3453	198	4	,	,	PUNCT
fnp-3453	198	5	with	with	ADP
fnp-3453	198	6	the	the	DET
fnp-3453	198	7	majority	majority	NOUN
fnp-3453	198	8	being	be	AUX
fnp-3453	198	9	decreased	decrease	VERB
fnp-3453	198	10	compared	compare	VERB
fnp-3453	198	11	to	to	ADP
fnp-3453	198	12	control	control	NOUN
fnp-3453	198	13	(	(	PUNCT
fnp-3453	198	14	figure	figure	NOUN
fnp-3453	198	15	6	6	NUM
fnp-3453	198	16	g	g	NOUN
fnp-3453	198	17	)	)	PUNCT
fnp-3453	198	18	.	.	PUNCT
fnp-3453	199	1	vascular	vascular	NOUN
fnp-3453	199	2	had	have	VERB
fnp-3453	199	3	16	16	NUM
fnp-3453	199	4	processes	process	NOUN
fnp-3453	199	5	with	with	ADP
fnp-3453	199	6	all	all	PRON
fnp-3453	199	7	but	but	SCONJ
fnp-3453	199	8	one	one	NUM
fnp-3453	199	9	observed	observe	VERB
fnp-3453	199	10	to	to	PART
fnp-3453	199	11	decrease	decrease	VERB
fnp-3453	199	12	compared	compare	VERB
fnp-3453	199	13	to	to	ADP
fnp-3453	199	14	controls	control	NOUN
fnp-3453	199	15	(	(	PUNCT
fnp-3453	199	16	figure	figure	NOUN
fnp-3453	199	17	6h	6h	NUM
fnp-3453	199	18	)	)	PUNCT
fnp-3453	199	19	.	.	PUNCT
fnp-3453	200	1	endocytosis	endocytosis	NOUN
fnp-3453	200	2	/	/	SYM
fnp-3453	200	3	exocytosis	exocytosis	NOUN
fnp-3453	200	4	had	have	VERB
fnp-3453	200	5	9	9	NUM
fnp-3453	200	6	processes	process	NOUN
fnp-3453	200	7	with	with	ADP
fnp-3453	200	8	an	an	DET
fnp-3453	200	9	even	even	ADV
fnp-3453	200	10	split	split	NOUN
fnp-3453	200	11	of	of	ADP
fnp-3453	200	12	changes	change	NOUN
fnp-3453	200	13	(	(	PUNCT
fnp-3453	200	14	figure	figure	NOUN
fnp-3453	200	15	6i	6i	NUM
fnp-3453	200	16	)	)	PUNCT
fnp-3453	200	17	.	.	PUNCT
fnp-3453	201	1	protein	protein	NOUN
fnp-3453	201	2	processing	processing	NOUN
fnp-3453	201	3	had	have	VERB
fnp-3453	201	4	22	22	NUM
fnp-3453	201	5	processes	process	NOUN
fnp-3453	201	6	with	with	ADP
fnp-3453	201	7	an	an	DET
fnp-3453	201	8	even	even	ADV
fnp-3453	201	9	split	split	NOUN
fnp-3453	201	10	of	of	ADP
fnp-3453	201	11	changes	change	NOUN
fnp-3453	201	12	(	(	PUNCT
fnp-3453	201	13	figure	figure	NOUN
fnp-3453	201	14	6j	6j	NUM
fnp-3453	201	15	)	)	PUNCT
fnp-3453	201	16	.	.	PUNCT
fnp-3453	202	1	finally	finally	ADV
fnp-3453	202	2	,	,	PUNCT
fnp-3453	202	3	the	the	DET
fnp-3453	202	4	12	12	NUM
fnp-3453	202	5	processes	process	NOUN
fnp-3453	202	6	that	that	PRON
fnp-3453	202	7	did	do	AUX
fnp-3453	202	8	n’t	not	PART
fnp-3453	202	9	fall	fall	VERB
fnp-3453	202	10	in	in	ADP
fnp-3453	202	11	the	the	DET
fnp-3453	202	12	previous	previous	ADJ
fnp-3453	202	13	10	10	NUM
fnp-3453	202	14	categories	category	NOUN
fnp-3453	202	15	were	be	AUX
fnp-3453	202	16	assigned	assign	VERB
fnp-3453	202	17	to	to	ADP
fnp-3453	202	18	an	an	DET
fnp-3453	202	19	“	"	PUNCT
fnp-3453	202	20	other	other	ADJ
fnp-3453	202	21	”	"	PUNCT
fnp-3453	202	22	category	category	NOUN
fnp-3453	202	23	and	and	CCONJ
fnp-3453	202	24	were	be	AUX
fnp-3453	202	25	all	all	ADV
fnp-3453	202	26	decreased	decrease	VERB
fnp-3453	202	27	compared	compare	VERB
fnp-3453	202	28	to	to	ADP
fnp-3453	202	29	control	control	NOUN
fnp-3453	202	30	(	(	PUNCT
fnp-3453	202	31	figure	figure	NOUN
fnp-3453	202	32	6k	6k	NOUN
fnp-3453	202	33	)	)	PUNCT
fnp-3453	202	34	.	.	PUNCT
fnp-3453	203	1	overall	overall	ADV
fnp-3453	203	2	,	,	PUNCT
fnp-3453	203	3	rhi	rhi	PROPN
fnp-3453	203	4	and	and	CCONJ
fnp-3453	203	5	cte	cte	PROPN
fnp-3453	203	6	had	have	VERB
fnp-3453	203	7	similar	similar	ADJ
fnp-3453	203	8	changes	change	NOUN
fnp-3453	203	9	compared	compare	VERB
fnp-3453	203	10	to	to	ADP
fnp-3453	203	11	controls	control	NOUN
fnp-3453	203	12	.	.	PUNCT
fnp-3453	204	1	for	for	ADP
fnp-3453	204	2	rhi	rhi	NOUN
fnp-3453	204	3	-	-	PUNCT
fnp-3453	204	4	control	control	PROPN
fnp-3453	204	5	and	and	CCONJ
fnp-3453	204	6	cte	cte	NOUN
fnp-3453	204	7	-	-	PUNCT
fnp-3453	204	8	control	control	NOUN
fnp-3453	204	9	comparisons	comparison	NOUN
fnp-3453	204	10	that	that	PRON
fnp-3453	204	11	did	do	AUX
fnp-3453	204	12	not	not	PART
fnp-3453	204	13	have	have	VERB
fnp-3453	204	14	the	the	DET
fnp-3453	204	15	same	same	ADJ
fnp-3453	204	16	direction	direction	NOUN
fnp-3453	204	17	of	of	ADP
fnp-3453	204	18	effect	effect	NOUN
fnp-3453	204	19	,	,	PUNCT
fnp-3453	204	20	cte	cte	NOUN
fnp-3453	204	21	-	-	PUNCT
fnp-3453	204	22	control	control	NOUN
fnp-3453	204	23	comparisons	comparison	NOUN
fnp-3453	204	24	always	always	ADV
fnp-3453	204	25	had	have	AUX
fnp-3453	204	26	reduced	reduce	VERB
fnp-3453	204	27	enrichment	enrichment	NOUN
fnp-3453	204	28	of	of	ADP
fnp-3453	204	29	those	those	DET
fnp-3453	204	30	processes	process	NOUN
fnp-3453	204	31	.	.	PUNCT
fnp-3453	205	1	figure	figure	VERB
fnp-3453	205	2	6	6	NUM
fnp-3453	205	3	.	.	PUNCT
fnp-3453	205	4	heatmap	heatmap	NOUN
fnp-3453	205	5	of	of	ADP
fnp-3453	205	6	sulcal	sulcal	ADJ
fnp-3453	205	7	specific	specific	ADJ
fnp-3453	205	8	gsea	gsea	ADJ
fnp-3453	205	9	biological	biological	ADJ
fnp-3453	205	10	processes	process	NOUN
fnp-3453	205	11	that	that	PRON
fnp-3453	205	12	change	change	VERB
fnp-3453	205	13	in	in	ADP
fnp-3453	205	14	rhi	rhi	PROPN
fnp-3453	205	15	and	and	CCONJ
fnp-3453	205	16	cte	cte	NOUN
fnp-3453	205	17	compared	compare	VERB
fnp-3453	205	18	to	to	ADP
fnp-3453	205	19	controlthe	controlthe	PROPN
fnp-3453	205	20	rhi	rhi	PROPN
fnp-3453	205	21	and	and	CCONJ
fnp-3453	205	22	cte	cte	PROPN
fnp-3453	205	23	gsea	gsea	NOUN
fnp-3453	205	24	processes	process	NOUN
fnp-3453	205	25	that	that	PRON
fnp-3453	205	26	were	be	AUX
fnp-3453	205	27	found	find	VERB
fnp-3453	205	28	to	to	PART
fnp-3453	205	29	be	be	AUX
fnp-3453	205	30	specifically	specifically	ADV
fnp-3453	205	31	altered	alter	VERB
fnp-3453	205	32	in	in	ADP
fnp-3453	205	33	the	the	DET
fnp-3453	205	34	sulcus	sulcus	NOUN
fnp-3453	205	35	were	be	AUX
fnp-3453	205	36	compared	compare	VERB
fnp-3453	205	37	to	to	ADP
fnp-3453	205	38	the	the	DET
fnp-3453	205	39	control	control	NOUN
fnp-3453	205	40	.	.	PUNCT
fnp-3453	206	1	each	each	DET
fnp-3453	206	2	process	process	NOUN
fnp-3453	206	3	was	be	AUX
fnp-3453	206	4	again	again	ADV
fnp-3453	206	5	assigned	assign	VERB
fnp-3453	206	6	to	to	ADP
fnp-3453	206	7	a	a	DET
fnp-3453	206	8	greater	great	ADJ
fnp-3453	206	9	overall	overall	ADJ
fnp-3453	206	10	biological	biological	ADJ
fnp-3453	206	11	category	category	NOUN
fnp-3453	206	12	:	:	PUNCT
fnp-3453	206	13	a	a	X
fnp-3453	206	14	)	)	PUNCT
fnp-3453	206	15	immune	immune	ADJ
fnp-3453	206	16	,	,	PUNCT
fnp-3453	206	17	b	b	NOUN
fnp-3453	206	18	)	)	PUNCT
fnp-3453	206	19	transcriptional	transcriptional	ADJ
fnp-3453	206	20	/	/	SYM
fnp-3453	206	21	translational	translational	ADJ
fnp-3453	206	22	,	,	PUNCT
fnp-3453	206	23	c	c	NOUN
fnp-3453	206	24	)	)	PUNCT
fnp-3453	206	25	neuronal	neuronal	ADJ
fnp-3453	206	26	,	,	PUNCT
fnp-3453	206	27	d	d	NOUN
fnp-3453	206	28	)	)	PUNCT
fnp-3453	206	29	cytoskeletal	cytoskeletal	NOUN
fnp-3453	206	30	,	,	PUNCT
fnp-3453	206	31	e	e	NOUN
fnp-3453	206	32	)	)	PUNCT
fnp-3453	206	33	extracellular	extracellular	ADJ
fnp-3453	206	34	matrix	matrix	NOUN
fnp-3453	206	35	,	,	PUNCT
fnp-3453	206	36	f	f	X
fnp-3453	206	37	)	)	PUNCT
fnp-3453	206	38	mitochondria	mitochondria	NOUN
fnp-3453	206	39	/	/	SYM
fnp-3453	206	40	metabolism	metabolism	NOUN
fnp-3453	206	41	,	,	PUNCT
fnp-3453	206	42	g	g	NOUN
fnp-3453	206	43	)	)	PUNCT
fnp-3453	206	44	signaling	signal	VERB
fnp-3453	206	45	,	,	PUNCT
fnp-3453	206	46	h	h	NOUN
fnp-3453	206	47	)	)	PUNCT
fnp-3453	206	48	vascular	vascular	NOUN
fnp-3453	206	49	,	,	PUNCT
fnp-3453	206	50	i	i	NOUN
fnp-3453	206	51	)	)	PUNCT
fnp-3453	206	52	endocytosis	endocytosis	NOUN
fnp-3453	206	53	/	/	SYM
fnp-3453	206	54	exocytosis	exocytosis	NOUN
fnp-3453	206	55	,	,	PUNCT
fnp-3453	206	56	j	j	NOUN
fnp-3453	206	57	)	)	PUNCT
fnp-3453	206	58	protein	protein	NOUN
fnp-3453	206	59	processing	processing	NOUN
fnp-3453	206	60	,	,	PUNCT
fnp-3453	206	61	k	k	NOUN
fnp-3453	206	62	)	)	PUNCT
fnp-3453	206	63	other	other	ADJ
fnp-3453	206	64	.	.	PUNCT
fnp-3453	207	1	[	[	AUX
fnp-3453	207	2	please	please	INTJ
fnp-3453	207	3	click	click	VERB
fnp-3453	207	4	on	on	ADP
fnp-3453	207	5	the	the	DET
fnp-3453	207	6	figure	figure	NOUN
fnp-3453	207	7	to	to	PART
fnp-3453	207	8	download	download	VERB
fnp-3453	207	9	a	a	DET
fnp-3453	207	10	high	high	ADJ
fnp-3453	207	11	-	-	PUNCT
fnp-3453	207	12	resolution	resolution	NOUN
fnp-3453	207	13	version	version	NOUN
fnp-3453	207	14	]	]	X
fnp-3453	207	15	common	common	ADJ
fnp-3453	207	16	and	and	CCONJ
fnp-3453	207	17	unique	unique	ADJ
fnp-3453	207	18	genes	gene	NOUN
fnp-3453	207	19	found	find	VERB
fnp-3453	207	20	in	in	ADP
fnp-3453	207	21	the	the	DET
fnp-3453	207	22	sulcus	sulcus	NOUN
fnp-3453	207	23	across	across	ADP
fnp-3453	207	24	disease	disease	NOUN
fnp-3453	207	25	groups	group	NOUN
fnp-3453	207	26	finally	finally	ADV
fnp-3453	207	27	,	,	PUNCT
fnp-3453	207	28	using	use	VERB
fnp-3453	207	29	the	the	DET
fnp-3453	207	30	differentially	differentially	ADV
fnp-3453	207	31	expressed	express	VERB
fnp-3453	207	32	gene	gene	NOUN
fnp-3453	207	33	results	result	NOUN
fnp-3453	207	34	comparing	compare	VERB
fnp-3453	207	35	the	the	DET
fnp-3453	207	36	sulcus	sulcus	NOUN
fnp-3453	207	37	to	to	ADP
fnp-3453	207	38	the	the	DET
fnp-3453	207	39	crest	crest	NOUN
fnp-3453	207	40	(	(	PUNCT
fnp-3453	207	41	figure	figure	NOUN
fnp-3453	207	42	1b	1b	NUM
fnp-3453	207	43	,	,	PUNCT
fnp-3453	207	44	comparison	comparison	NOUN
fnp-3453	207	45	2	2	NUM
fnp-3453	207	46	)	)	PUNCT
fnp-3453	207	47	,	,	PUNCT
fnp-3453	207	48	we	we	PRON
fnp-3453	207	49	wanted	want	VERB
fnp-3453	207	50	to	to	PART
fnp-3453	207	51	examine	examine	VERB
fnp-3453	207	52	if	if	SCONJ
fnp-3453	207	53	there	there	PRON
fnp-3453	207	54	were	be	VERB
fnp-3453	207	55	any	any	DET
fnp-3453	207	56	sulcal	sulcal	ADJ
fnp-3453	207	57	specific	specific	ADJ
fnp-3453	207	58	alterations	alteration	NOUN
fnp-3453	207	59	that	that	PRON
fnp-3453	207	60	were	be	AUX
fnp-3453	207	61	unique	unique	ADJ
fnp-3453	207	62	or	or	CCONJ
fnp-3453	207	63	common	common	ADJ
fnp-3453	207	64	across	across	ADP
fnp-3453	207	65	each	each	DET
fnp-3453	207	66	group	group	NOUN
fnp-3453	207	67	(	(	PUNCT
fnp-3453	207	68	figure	figure	NOUN
fnp-3453	207	69	7	7	NUM
fnp-3453	207	70	)	)	PUNCT
fnp-3453	207	71	.	.	PUNCT
fnp-3453	208	1	first	first	ADV
fnp-3453	208	2	,	,	PUNCT
fnp-3453	208	3	we	we	PRON
fnp-3453	208	4	examined	examine	VERB
fnp-3453	208	5	what	what	PRON
fnp-3453	208	6	sulcal	sulcal	ADJ
fnp-3453	208	7	specific	specific	ADJ
fnp-3453	208	8	genes	gene	NOUN
fnp-3453	208	9	were	be	AUX
fnp-3453	208	10	commonly	commonly	ADV
fnp-3453	208	11	altered	alter	VERB
fnp-3453	208	12	in	in	ADP
fnp-3453	208	13	all	all	DET
fnp-3453	208	14	three	three	NUM
fnp-3453	208	15	groups	group	NOUN
fnp-3453	208	16	.	.	PUNCT
fnp-3453	209	1	333	333	NUM
fnp-3453	209	2	genes	gene	NOUN
fnp-3453	209	3	were	be	AUX
fnp-3453	209	4	differentially	differentially	ADV
fnp-3453	209	5	expressed	express	VERB
fnp-3453	209	6	in	in	ADP
fnp-3453	209	7	the	the	DET
fnp-3453	209	8	sulcus	sulcus	NOUN
fnp-3453	209	9	compared	compare	VERB
fnp-3453	209	10	with	with	ADP
fnp-3453	209	11	the	the	DET
fnp-3453	209	12	crest	crest	NOUN
fnp-3453	209	13	among	among	ADP
fnp-3453	209	14	all	all	DET
fnp-3453	209	15	three	three	NUM
fnp-3453	209	16	groups	group	NOUN
fnp-3453	209	17	(	(	PUNCT
fnp-3453	209	18	figure	figure	NOUN
fnp-3453	209	19	7a	7a	NUM
fnp-3453	209	20	)	)	PUNCT
fnp-3453	209	21	.	.	PUNCT
fnp-3453	210	1	331	331	NUM
fnp-3453	210	2	of	of	ADP
fnp-3453	210	3	333	333	NUM
fnp-3453	210	4	genes	gene	NOUN
fnp-3453	210	5	had	have	VERB
fnp-3453	210	6	the	the	DET
fnp-3453	210	7	same	same	ADJ
fnp-3453	210	8	direction	direction	NOUN
fnp-3453	210	9	of	of	ADP
fnp-3453	210	10	effect	effect	NOUN
fnp-3453	210	11	among	among	ADP
fnp-3453	210	12	all	all	DET
fnp-3453	210	13	three	three	NUM
fnp-3453	210	14	diagnostic	diagnostic	ADJ
fnp-3453	210	15	groups	group	NOUN
fnp-3453	210	16	(	(	PUNCT
fnp-3453	210	17	figure	figure	NOUN
fnp-3453	210	18	7b	7b	NOUN
fnp-3453	210	19	)	)	PUNCT
fnp-3453	210	20	.	.	PUNCT
fnp-3453	211	1	only	only	ADV
fnp-3453	211	2	2	2	NUM
fnp-3453	211	3	genes	gene	NOUN
fnp-3453	211	4	,	,	PUNCT
fnp-3453	211	5	kiaa2022	kiaa2022	PROPN
fnp-3453	211	6	(	(	PUNCT
fnp-3453	211	7	up	up	ADP
fnp-3453	211	8	in	in	ADP
fnp-3453	211	9	rhi	rhi	NOUN
fnp-3453	211	10	)	)	PUNCT
fnp-3453	211	11	and	and	CCONJ
fnp-3453	211	12	plekhh2	plekhh2	NOUN
fnp-3453	211	13	(	(	PUNCT
fnp-3453	211	14	down	down	ADP
fnp-3453	211	15	in	in	ADP
fnp-3453	211	16	rhi	rhi	PROPN
fnp-3453	211	17	)	)	PUNCT
fnp-3453	211	18	,	,	PUNCT
fnp-3453	211	19	had	have	VERB
fnp-3453	211	20	a	a	DET
fnp-3453	211	21	conflicting	conflicting	ADJ
fnp-3453	211	22	direction	direction	NOUN
fnp-3453	211	23	of	of	ADP
fnp-3453	211	24	effect	effect	NOUN
fnp-3453	211	25	in	in	ADP
fnp-3453	211	26	rhi	rhi	PROPN
fnp-3453	211	27	compared	compare	VERB
fnp-3453	211	28	to	to	ADP
fnp-3453	211	29	control	control	NOUN
fnp-3453	211	30	and	and	CCONJ
fnp-3453	211	31	cte	cte	NOUN
fnp-3453	211	32	.	.	PUNCT
fnp-3453	212	1	to	to	PART
fnp-3453	212	2	better	well	ADV
fnp-3453	212	3	understand	understand	VERB
fnp-3453	212	4	the	the	DET
fnp-3453	212	5	biological	biological	ADJ
fnp-3453	212	6	relevance	relevance	NOUN
fnp-3453	212	7	of	of	ADP
fnp-3453	212	8	those	those	DET
fnp-3453	212	9	common	common	ADJ
fnp-3453	212	10	genes	gene	NOUN
fnp-3453	212	11	,	,	PUNCT
fnp-3453	212	12	gene	gene	NOUN
fnp-3453	212	13	ontology	ontology	NOUN
fnp-3453	212	14	(	(	PUNCT
fnp-3453	212	15	go	go	VERB
fnp-3453	212	16	)	)	PUNCT
fnp-3453	212	17	analysis	analysis	NOUN
fnp-3453	212	18	was	be	AUX
fnp-3453	212	19	performed	perform	VERB
fnp-3453	212	20	(	(	PUNCT
fnp-3453	212	21	figure	figure	NOUN
fnp-3453	212	22	7c	7c	NUM
fnp-3453	212	23	)	)	PUNCT
fnp-3453	212	24	.	.	PUNCT
fnp-3453	213	1	the	the	DET
fnp-3453	213	2	most	most	ADV
fnp-3453	213	3	highly	highly	ADV
fnp-3453	213	4	significant	significant	ADJ
fnp-3453	213	5	go	go	NOUN
fnp-3453	213	6	term	term	NOUN
fnp-3453	213	7	of	of	ADP
fnp-3453	213	8	the	the	DET
fnp-3453	213	9	common	common	ADJ
fnp-3453	213	10	genes	gene	NOUN
fnp-3453	213	11	was	be	AUX
fnp-3453	213	12	“	"	PUNCT
fnp-3453	213	13	gliogenesis	gliogenesis	NOUN
fnp-3453	213	14	”	"	PUNCT
fnp-3453	213	15	,	,	PUNCT
fnp-3453	213	16	suggesting	suggest	VERB
fnp-3453	213	17	an	an	DET
fnp-3453	213	18	altered	altered	ADJ
fnp-3453	213	19	glial	glial	ADJ
fnp-3453	213	20	response	response	NOUN
fnp-3453	213	21	is	be	AUX
fnp-3453	213	22	an	an	DET
fnp-3453	213	23	innate	innate	ADJ
fnp-3453	213	24	feature	feature	NOUN
fnp-3453	213	25	of	of	ADP
fnp-3453	213	26	the	the	DET
fnp-3453	213	27	sulcus	sulcus	NOUN
fnp-3453	213	28	compared	compare	VERB
fnp-3453	213	29	to	to	ADP
fnp-3453	213	30	other	other	ADJ
fnp-3453	213	31	brain	brain	NOUN
fnp-3453	213	32	regions	region	NOUN
fnp-3453	213	33	.	.	PUNCT
fnp-3453	214	1	when	when	SCONJ
fnp-3453	214	2	examining	examine	VERB
fnp-3453	214	3	the	the	DET
fnp-3453	214	4	rest	rest	NOUN
fnp-3453	214	5	of	of	ADP
fnp-3453	214	6	the	the	DET
fnp-3453	214	7	top	top	ADJ
fnp-3453	214	8	20	20	NUM
fnp-3453	214	9	significant	significant	ADJ
fnp-3453	214	10	processes	process	NOUN
fnp-3453	214	11	,	,	PUNCT
fnp-3453	214	12	many	many	ADJ
fnp-3453	214	13	processes	process	NOUN
fnp-3453	214	14	were	be	AUX
fnp-3453	214	15	observed	observe	VERB
fnp-3453	214	16	to	to	PART
fnp-3453	214	17	encompass	encompass	VERB
fnp-3453	214	18	development	development	NOUN
fnp-3453	214	19	,	,	PUNCT
fnp-3453	214	20	homeostasis	homeostasis	NOUN
fnp-3453	214	21	,	,	PUNCT
fnp-3453	214	22	and	and	CCONJ
fnp-3453	214	23	organization	organization	NOUN
fnp-3453	214	24	.	.	PUNCT
fnp-3453	215	1	we	we	PRON
fnp-3453	215	2	then	then	ADV
fnp-3453	215	3	wanted	want	VERB
fnp-3453	215	4	to	to	PART
fnp-3453	215	5	determine	determine	VERB
fnp-3453	215	6	which	which	PRON
fnp-3453	215	7	differentially	differentially	ADV
fnp-3453	215	8	expressed	express	VERB
fnp-3453	215	9	genes	gene	NOUN
fnp-3453	215	10	in	in	ADP
fnp-3453	215	11	the	the	DET
fnp-3453	215	12	sulcus	sulcus	NOUN
fnp-3453	215	13	compared	compare	VERB
fnp-3453	215	14	with	with	ADP
fnp-3453	215	15	the	the	DET
fnp-3453	215	16	crest	crest	NOUN
fnp-3453	215	17	were	be	AUX
fnp-3453	215	18	unique	unique	ADJ
fnp-3453	215	19	to	to	ADP
fnp-3453	215	20	each	each	DET
fnp-3453	215	21	diagnostic	diagnostic	ADJ
fnp-3453	215	22	group	group	NOUN
fnp-3453	215	23	.	.	PUNCT
fnp-3453	216	1	a	a	DET
fnp-3453	216	2	stringent	stringent	ADJ
fnp-3453	216	3	criteria	criterion	NOUN
fnp-3453	216	4	was	be	AUX
fnp-3453	216	5	used	use	VERB
fnp-3453	216	6	to	to	PART
fnp-3453	216	7	avoid	avoid	VERB
fnp-3453	216	8	including	include	VERB
fnp-3453	216	9	any	any	DET
fnp-3453	216	10	gene	gene	NOUN
fnp-3453	216	11	that	that	PRON
fnp-3453	216	12	was	be	AUX
fnp-3453	216	13	significant	significant	ADJ
fnp-3453	216	14	in	in	ADP
fnp-3453	216	15	one	one	NUM
fnp-3453	216	16	group	group	NOUN
fnp-3453	216	17	but	but	CCONJ
fnp-3453	216	18	also	also	ADV
fnp-3453	216	19	had	have	VERB
fnp-3453	216	20	p	p	NOUN
fnp-3453	216	21	values	value	NOUN
fnp-3453	216	22	close	close	ADJ
fnp-3453	216	23	to	to	PART
fnp-3453	216	24	significant	significant	ADJ
fnp-3453	216	25	in	in	ADP
fnp-3453	216	26	the	the	DET
fnp-3453	216	27	other	other	ADJ
fnp-3453	216	28	two	two	NUM
fnp-3453	216	29	suggesting	suggest	VERB
fnp-3453	216	30	they	they	PRON
fnp-3453	216	31	could	could	AUX
fnp-3453	216	32	be	be	AUX
fnp-3453	216	33	common	common	ADJ
fnp-3453	216	34	genes	gene	NOUN
fnp-3453	216	35	if	if	SCONJ
fnp-3453	216	36	power	power	NOUN
fnp-3453	216	37	were	be	AUX
fnp-3453	216	38	increased	increase	VERB
fnp-3453	216	39	.	.	PUNCT
fnp-3453	217	1	therefore	therefore	ADV
fnp-3453	217	2	,	,	PUNCT
fnp-3453	217	3	only	only	ADV
fnp-3453	217	4	genes	gene	NOUN
fnp-3453	217	5	that	that	PRON
fnp-3453	217	6	had	have	VERB
fnp-3453	217	7	a	a	DET
fnp-3453	217	8	nominal	nominal	ADJ
fnp-3453	217	9	p	p	X
fnp-3453	217	10	<	<	X
fnp-3453	217	11	0.05	0.05	NUM
fnp-3453	217	12	in	in	ADP
fnp-3453	217	13	one	one	NUM
fnp-3453	217	14	group	group	NOUN
fnp-3453	217	15	and	and	CCONJ
fnp-3453	217	16	a	a	DET
fnp-3453	217	17	p	p	X
fnp-3453	217	18	>	>	X
fnp-3453	217	19	0.25	0.25	NUM
fnp-3453	217	20	in	in	ADP
fnp-3453	217	21	all	all	DET
fnp-3453	217	22	others	other	NOUN
fnp-3453	217	23	were	be	AUX
fnp-3453	217	24	marked	mark	VERB
fnp-3453	217	25	to	to	PART
fnp-3453	217	26	be	be	AUX
fnp-3453	217	27	“	"	PUNCT
fnp-3453	217	28	uniquely	uniquely	ADV
fnp-3453	217	29	”	"	PUNCT
fnp-3453	217	30	altered	alter	VERB
fnp-3453	217	31	.	.	PUNCT
fnp-3453	218	1	1074	1074	NUM
fnp-3453	218	2	genes	gene	NOUN
fnp-3453	218	3	were	be	AUX
fnp-3453	218	4	found	find	VERB
fnp-3453	218	5	to	to	PART
fnp-3453	218	6	be	be	AUX
fnp-3453	218	7	uniquely	uniquely	ADV
fnp-3453	218	8	altered	alter	VERB
fnp-3453	218	9	in	in	ADP
fnp-3453	218	10	the	the	DET
fnp-3453	218	11	control	control	NOUN
fnp-3453	218	12	sulcus	sulcus	NOUN
fnp-3453	218	13	with	with	ADP
fnp-3453	218	14	806	806	NUM
fnp-3453	218	15	being	be	AUX
fnp-3453	218	16	increased	increase	VERB
fnp-3453	218	17	and	and	CCONJ
fnp-3453	218	18	268	268	NUM
fnp-3453	218	19	being	be	AUX
fnp-3453	218	20	decreased	decrease	VERB
fnp-3453	218	21	compared	compare	VERB
fnp-3453	218	22	to	to	ADP
fnp-3453	218	23	the	the	DET
fnp-3453	218	24	crest	crest	NOUN
fnp-3453	218	25	(	(	PUNCT
fnp-3453	218	26	figure	figure	NOUN
fnp-3453	218	27	7d	7d	NUM
fnp-3453	218	28	)	)	PUNCT
fnp-3453	218	29	.	.	PUNCT
fnp-3453	219	1	168	168	NUM
fnp-3453	219	2	genes	gene	NOUN
fnp-3453	219	3	had	have	VERB
fnp-3453	219	4	an	an	DET
fnp-3453	219	5	fdr	fdr	PROPN
fnp-3453	219	6	<	<	X
fnp-3453	219	7	0.1	0.1	NUM
fnp-3453	219	8	.	.	PUNCT
fnp-3453	220	1	when	when	SCONJ
fnp-3453	220	2	observing	observe	VERB
fnp-3453	220	3	the	the	DET
fnp-3453	220	4	go	go	NOUN
fnp-3453	220	5	processes	process	NOUN
fnp-3453	220	6	of	of	ADP
fnp-3453	220	7	the	the	DET
fnp-3453	220	8	unique	unique	ADJ
fnp-3453	220	9	control	control	NOUN
fnp-3453	220	10	genes	gene	NOUN
fnp-3453	220	11	,	,	PUNCT
fnp-3453	220	12	developmental	developmental	ADJ
fnp-3453	220	13	and	and	CCONJ
fnp-3453	220	14	immune	immune	ADJ
fnp-3453	220	15	regulation	regulation	NOUN
fnp-3453	220	16	processes	process	NOUN
fnp-3453	220	17	appeared	appear	VERB
fnp-3453	220	18	to	to	PART
fnp-3453	220	19	be	be	AUX
fnp-3453	220	20	the	the	DET
fnp-3453	220	21	most	most	ADV
fnp-3453	220	22	prominent	prominent	ADJ
fnp-3453	220	23	(	(	PUNCT
fnp-3453	220	24	figure	figure	NOUN
fnp-3453	220	25	7e	7e	NUM
fnp-3453	220	26	)	)	PUNCT
fnp-3453	220	27	.	.	PUNCT
fnp-3453	221	1	389	389	NUM
fnp-3453	221	2	genes	gene	NOUN
fnp-3453	221	3	were	be	AUX
fnp-3453	221	4	found	find	VERB
fnp-3453	221	5	to	to	PART
fnp-3453	221	6	be	be	AUX
fnp-3453	221	7	unique	unique	ADJ
fnp-3453	221	8	in	in	ADP
fnp-3453	221	9	the	the	DET
fnp-3453	221	10	rhi	rhi	PROPN
fnp-3453	221	11	group	group	NOUN
fnp-3453	221	12	.	.	PUNCT
fnp-3453	222	1	192	192	NUM
fnp-3453	222	2	genes	gene	NOUN
fnp-3453	222	3	were	be	AUX
fnp-3453	222	4	increased	increase	VERB
fnp-3453	222	5	,	,	PUNCT
fnp-3453	222	6	and	and	CCONJ
fnp-3453	222	7	197	197	NUM
fnp-3453	222	8	genes	gene	NOUN
fnp-3453	222	9	were	be	AUX
fnp-3453	222	10	decreased	decrease	VERB
fnp-3453	222	11	in	in	ADP
fnp-3453	222	12	the	the	DET
fnp-3453	222	13	rhi	rhi	PROPN
fnp-3453	222	14	sulcus	sulcus	PROPN
fnp-3453	222	15	(	(	PUNCT
fnp-3453	222	16	figure	figure	NOUN
fnp-3453	222	17	7f	7f	NUM
fnp-3453	222	18	)	)	PUNCT
fnp-3453	222	19	.	.	PUNCT
fnp-3453	223	1	no	no	DET
fnp-3453	223	2	rhi	rhi	PROPN
fnp-3453	223	3	unique	unique	ADJ
fnp-3453	223	4	gene	gene	NOUN
fnp-3453	223	5	met	meet	VERB
fnp-3453	223	6	fdr	fdr	PROPN
fnp-3453	223	7	corrected	correct	VERB
fnp-3453	223	8	significance	significance	NOUN
fnp-3453	223	9	.	.	PUNCT
fnp-3453	224	1	using	use	VERB
fnp-3453	224	2	go	go	VERB
fnp-3453	224	3	analysis	analysis	NOUN
fnp-3453	224	4	,	,	PUNCT
fnp-3453	224	5	it	it	PRON
fnp-3453	224	6	was	be	AUX
fnp-3453	224	7	observed	observe	VERB
fnp-3453	224	8	that	that	SCONJ
fnp-3453	224	9	many	many	ADJ
fnp-3453	224	10	of	of	ADP
fnp-3453	224	11	the	the	DET
fnp-3453	224	12	processes	process	NOUN
fnp-3453	224	13	were	be	AUX
fnp-3453	224	14	metabolic	metabolic	ADJ
fnp-3453	224	15	or	or	CCONJ
fnp-3453	224	16	transcriptionally	transcriptionally	ADV
fnp-3453	224	17	related	relate	VERB
fnp-3453	224	18	(	(	PUNCT
fnp-3453	224	19	figure	figure	NOUN
fnp-3453	224	20	6	6	NUM
fnp-3453	224	21	g	g	NOUN
fnp-3453	224	22	)	)	PUNCT
fnp-3453	224	23	.	.	PUNCT
fnp-3453	225	1	finally	finally	ADV
fnp-3453	225	2	,	,	PUNCT
fnp-3453	225	3	531	531	NUM
fnp-3453	225	4	genes	gene	NOUN
fnp-3453	225	5	were	be	AUX
fnp-3453	225	6	uniquely	uniquely	ADV
fnp-3453	225	7	altered	alter	VERB
fnp-3453	225	8	in	in	ADP
fnp-3453	225	9	the	the	DET
fnp-3453	225	10	cte	cte	NOUN
fnp-3453	225	11	sulcus	sulcus	NOUN
fnp-3453	225	12	.	.	PUNCT
fnp-3453	226	1	239	239	NUM
fnp-3453	226	2	genes	gene	NOUN
fnp-3453	226	3	were	be	AUX
fnp-3453	226	4	increased	increase	VERB
fnp-3453	226	5	,	,	PUNCT
fnp-3453	226	6	and	and	CCONJ
fnp-3453	226	7	292	292	NUM
fnp-3453	226	8	genes	gene	NOUN
fnp-3453	226	9	were	be	AUX
fnp-3453	226	10	decreased	decrease	VERB
fnp-3453	226	11	in	in	ADP
fnp-3453	226	12	the	the	DET
fnp-3453	226	13	sulcus	sulcus	NOUN
fnp-3453	226	14	relative	relative	ADJ
fnp-3453	226	15	to	to	ADP
fnp-3453	226	16	the	the	DET
fnp-3453	226	17	crest	crest	NOUN
fnp-3453	226	18	(	(	PUNCT
fnp-3453	226	19	figure	figure	NOUN
fnp-3453	226	20	7h	7h	PROPN
fnp-3453	226	21	)	)	PUNCT
fnp-3453	226	22	.	.	PUNCT
fnp-3453	227	1	136	136	NUM
fnp-3453	227	2	genes	gene	NOUN
fnp-3453	227	3	met	meet	VERB
fnp-3453	227	4	frd	frd	ADJ
fnp-3453	227	5	corrected	correct	VERB
fnp-3453	227	6	significance	significance	NOUN
fnp-3453	227	7	<	<	X
fnp-3453	227	8	0.1	0.1	NUM
fnp-3453	227	9	.	.	PUNCT
fnp-3453	228	1	go	go	VERB
fnp-3453	228	2	analysis	analysis	NOUN
fnp-3453	228	3	of	of	ADP
fnp-3453	228	4	cte	cte	NOUN
fnp-3453	228	5	specific	specific	ADJ
fnp-3453	228	6	biological	biological	ADJ
fnp-3453	228	7	processes	process	NOUN
fnp-3453	228	8	demonstrated	demonstrate	VERB
fnp-3453	228	9	immune	immune	ADJ
fnp-3453	228	10	and	and	CCONJ
fnp-3453	228	11	cell	cell	NOUN
fnp-3453	228	12	damage	damage	NOUN
fnp-3453	228	13	biological	biological	ADJ
fnp-3453	228	14	processes	process	NOUN
fnp-3453	228	15	(	(	PUNCT
fnp-3453	228	16	figure	figure	NOUN
fnp-3453	228	17	7i	7i	NUM
fnp-3453	228	18	)	)	PUNCT
fnp-3453	228	19	.	.	PUNCT
fnp-3453	229	1	figure	figure	VERB
fnp-3453	229	2	7	7	NUM
fnp-3453	229	3	.	.	PUNCT
fnp-3453	230	1	analysis	analysis	NOUN
fnp-3453	230	2	of	of	ADP
fnp-3453	230	3	common	common	ADJ
fnp-3453	230	4	and	and	CCONJ
fnp-3453	230	5	unique	unique	ADJ
fnp-3453	230	6	genes	gene	NOUN
fnp-3453	230	7	and	and	CCONJ
fnp-3453	230	8	biological	biological	ADJ
fnp-3453	230	9	process	process	NOUN
fnp-3453	230	10	found	find	VERB
fnp-3453	230	11	in	in	ADP
fnp-3453	230	12	the	the	DET
fnp-3453	230	13	sulcususing	sulcususe	VERB
fnp-3453	230	14	the	the	DET
fnp-3453	230	15	genes	gene	NOUN
fnp-3453	230	16	that	that	PRON
fnp-3453	230	17	were	be	AUX
fnp-3453	230	18	found	find	VERB
fnp-3453	230	19	to	to	PART
fnp-3453	230	20	be	be	AUX
fnp-3453	230	21	significantly	significantly	ADV
fnp-3453	230	22	altered	alter	VERB
fnp-3453	230	23	in	in	ADP
fnp-3453	230	24	the	the	DET
fnp-3453	230	25	sulcus	sulcus	NOUN
fnp-3453	230	26	compared	compare	VERB
fnp-3453	230	27	to	to	ADP
fnp-3453	230	28	the	the	DET
fnp-3453	230	29	crest	crest	NOUN
fnp-3453	230	30	,	,	PUNCT
fnp-3453	230	31	we	we	PRON
fnp-3453	230	32	compared	compare	VERB
fnp-3453	230	33	which	which	DET
fnp-3453	230	34	genes	gene	NOUN
fnp-3453	230	35	were	be	AUX
fnp-3453	230	36	common	common	ADJ
fnp-3453	230	37	to	to	ADP
fnp-3453	230	38	all	all	DET
fnp-3453	230	39	groups	group	NOUN
fnp-3453	230	40	and	and	CCONJ
fnp-3453	230	41	which	which	PRON
fnp-3453	230	42	were	be	AUX
fnp-3453	230	43	unique	unique	ADJ
fnp-3453	230	44	to	to	ADP
fnp-3453	230	45	each	each	DET
fnp-3453	230	46	condition	condition	NOUN
fnp-3453	230	47	.	.	PUNCT
fnp-3453	231	1	a	a	DET
fnp-3453	231	2	stringent	stringent	ADJ
fnp-3453	231	3	criteria	criterion	NOUN
fnp-3453	231	4	was	be	AUX
fnp-3453	231	5	used	use	VERB
fnp-3453	231	6	to	to	PART
fnp-3453	231	7	avoid	avoid	VERB
fnp-3453	231	8	including	include	VERB
fnp-3453	231	9	any	any	DET
fnp-3453	231	10	genes	gene	NOUN
fnp-3453	231	11	that	that	PRON
fnp-3453	231	12	were	be	AUX
fnp-3453	231	13	significant	significant	ADJ
fnp-3453	231	14	in	in	ADP
fnp-3453	231	15	one	one	NUM
fnp-3453	231	16	group	group	NOUN
fnp-3453	231	17	but	but	CCONJ
fnp-3453	231	18	also	also	ADV
fnp-3453	231	19	had	have	VERB
fnp-3453	231	20	p	p	NOUN
fnp-3453	231	21	values	value	NOUN
fnp-3453	231	22	close	close	ADJ
fnp-3453	231	23	to	to	ADP
fnp-3453	231	24	significant	significant	ADJ
fnp-3453	231	25	others	other	NOUN
fnp-3453	231	26	suggesting	suggest	VERB
fnp-3453	231	27	they	they	PRON
fnp-3453	231	28	could	could	AUX
fnp-3453	231	29	be	be	AUX
fnp-3453	231	30	common	common	ADJ
fnp-3453	231	31	genes	gene	NOUN
fnp-3453	231	32	if	if	SCONJ
fnp-3453	231	33	power	power	NOUN
fnp-3453	231	34	was	be	AUX
fnp-3453	231	35	increased	increase	VERB
fnp-3453	231	36	.	.	PUNCT
fnp-3453	232	1	therefore	therefore	ADV
fnp-3453	232	2	,	,	PUNCT
fnp-3453	232	3	only	only	ADV
fnp-3453	232	4	genes	gene	NOUN
fnp-3453	232	5	that	that	PRON
fnp-3453	232	6	had	have	VERB
fnp-3453	232	7	a	a	DET
fnp-3453	232	8	p	p	NOUN
fnp-3453	232	9	<	<	X
fnp-3453	232	10	0.05	0.05	NUM
fnp-3453	232	11	in	in	ADP
fnp-3453	232	12	one	one	NUM
fnp-3453	232	13	group	group	NOUN
fnp-3453	232	14	and	and	CCONJ
fnp-3453	232	15	a	a	DET
fnp-3453	232	16	p	p	X
fnp-3453	232	17	>	>	X
fnp-3453	232	18	0.25	0.25	NUM
fnp-3453	232	19	in	in	ADP
fnp-3453	232	20	all	all	DET
fnp-3453	232	21	others	other	NOUN
fnp-3453	232	22	were	be	AUX
fnp-3453	232	23	marked	mark	VERB
fnp-3453	232	24	to	to	PART
fnp-3453	232	25	be	be	AUX
fnp-3453	232	26	“	"	PUNCT
fnp-3453	232	27	uniquely	uniquely	ADV
fnp-3453	232	28	”	"	PUNCT
fnp-3453	232	29	altered	alter	VERB
fnp-3453	232	30	.	.	PUNCT
fnp-3453	233	1	a	a	X
fnp-3453	233	2	)	)	PUNCT
fnp-3453	233	3	a	a	DET
fnp-3453	233	4	venn	venn	PROPN
fnp-3453	233	5	diagram	diagram	NOUN
fnp-3453	233	6	of	of	ADP
fnp-3453	233	7	the	the	DET
fnp-3453	233	8	common	common	ADJ
fnp-3453	233	9	and	and	CCONJ
fnp-3453	233	10	unique	unique	ADJ
fnp-3453	233	11	genes	gene	NOUN
fnp-3453	233	12	found	find	VERB
fnp-3453	233	13	among	among	ADP
fnp-3453	233	14	all	all	DET
fnp-3453	233	15	three	three	NUM
fnp-3453	233	16	groups	group	NOUN
fnp-3453	233	17	.	.	PUNCT
fnp-3453	234	1	b	b	X
fnp-3453	234	2	)	)	PUNCT
fnp-3453	234	3	a	a	DET
fnp-3453	234	4	heatmap	heatmap	NOUN
fnp-3453	234	5	of	of	ADP
fnp-3453	234	6	the	the	DET
fnp-3453	234	7	common	common	ADJ
fnp-3453	234	8	genes	gene	NOUN
fnp-3453	234	9	showing	show	VERB
fnp-3453	234	10	similar	similar	ADJ
fnp-3453	234	11	directions	direction	NOUN
fnp-3453	234	12	of	of	ADP
fnp-3453	234	13	effect	effect	NOUN
fnp-3453	234	14	of	of	ADP
fnp-3453	234	15	the	the	DET
fnp-3453	234	16	majority	majority	NOUN
fnp-3453	234	17	of	of	ADP
fnp-3453	234	18	genes	gene	NOUN
fnp-3453	234	19	.	.	PUNCT
fnp-3453	235	1	c	c	X
fnp-3453	235	2	)	)	PUNCT
fnp-3453	235	3	go	go	VERB
fnp-3453	235	4	analysis	analysis	NOUN
fnp-3453	235	5	of	of	ADP
fnp-3453	235	6	the	the	DET
fnp-3453	235	7	common	common	ADJ
fnp-3453	235	8	genes	gene	NOUN
fnp-3453	235	9	.	.	PUNCT
fnp-3453	236	1	d	d	X
fnp-3453	236	2	)	)	PUNCT
fnp-3453	236	3	a	a	DET
fnp-3453	236	4	plot	plot	NOUN
fnp-3453	236	5	of	of	ADP
fnp-3453	236	6	the	the	DET
fnp-3453	236	7	unique	unique	ADJ
fnp-3453	236	8	sulcal	sulcal	ADJ
fnp-3453	236	9	genes	gene	NOUN
fnp-3453	236	10	found	find	VERB
fnp-3453	236	11	in	in	ADP
fnp-3453	236	12	control	control	NOUN
fnp-3453	236	13	cases	case	NOUN
fnp-3453	236	14	.	.	PUNCT
fnp-3453	237	1	e	e	X
fnp-3453	237	2	)	)	PUNCT
fnp-3453	237	3	go	go	VERB
fnp-3453	237	4	analysis	analysis	NOUN
fnp-3453	237	5	of	of	ADP
fnp-3453	237	6	the	the	DET
fnp-3453	237	7	unique	unique	ADJ
fnp-3453	237	8	control	control	NOUN
fnp-3453	237	9	genes	gene	NOUN
fnp-3453	237	10	.	.	PUNCT
fnp-3453	238	1	f	f	X
fnp-3453	238	2	)	)	PUNCT
fnp-3453	238	3	a	a	DET
fnp-3453	238	4	plot	plot	NOUN
fnp-3453	238	5	of	of	ADP
fnp-3453	238	6	the	the	DET
fnp-3453	238	7	unique	unique	ADJ
fnp-3453	238	8	sulcal	sulcal	ADJ
fnp-3453	238	9	genes	gene	NOUN
fnp-3453	238	10	found	find	VERB
fnp-3453	238	11	in	in	ADP
fnp-3453	238	12	rhi	rhi	PROPN
fnp-3453	238	13	cases	case	NOUN
fnp-3453	238	14	.	.	PUNCT
fnp-3453	239	1	g	g	NOUN
fnp-3453	239	2	)	)	PUNCT
fnp-3453	239	3	go	go	VERB
fnp-3453	239	4	analysis	analysis	NOUN
fnp-3453	239	5	of	of	ADP
fnp-3453	239	6	unique	unique	ADJ
fnp-3453	239	7	rhi	rhi	NOUN
fnp-3453	239	8	genes	gene	NOUN
fnp-3453	239	9	.	.	PUNCT
fnp-3453	240	1	h	h	X
fnp-3453	240	2	)	)	PUNCT
fnp-3453	240	3	a	a	DET
fnp-3453	240	4	plot	plot	NOUN
fnp-3453	240	5	of	of	ADP
fnp-3453	240	6	the	the	DET
fnp-3453	240	7	unique	unique	ADJ
fnp-3453	240	8	sulcal	sulcal	ADJ
fnp-3453	240	9	genes	gene	NOUN
fnp-3453	240	10	found	find	VERB
fnp-3453	240	11	in	in	ADP
fnp-3453	240	12	cte	cte	NOUN
fnp-3453	240	13	cases	case	NOUN
fnp-3453	240	14	.	.	PUNCT
fnp-3453	241	1	i	i	PRON
fnp-3453	241	2	)	)	PUNCT
fnp-3453	241	3	go	go	VERB
fnp-3453	241	4	analysis	analysis	NOUN
fnp-3453	241	5	of	of	ADP
fnp-3453	241	6	unique	unique	ADJ
fnp-3453	241	7	cte	cte	NOUN
fnp-3453	241	8	genes	gene	NOUN
fnp-3453	241	9	.	.	PUNCT
fnp-3453	242	1	in	in	ADP
fnp-3453	242	2	all	all	DET
fnp-3453	242	3	plots	plot	NOUN
fnp-3453	242	4	,	,	PUNCT
fnp-3453	242	5	red	red	ADJ
fnp-3453	242	6	dots	dot	NOUN
fnp-3453	242	7	denote	denote	VERB
fnp-3453	242	8	genes	gene	NOUN
fnp-3453	242	9	that	that	PRON
fnp-3453	242	10	met	meet	VERB
fnp-3453	242	11	fdr	fdr	PROPN
fnp-3453	242	12	adjusted	adjust	VERB
fnp-3453	242	13	p	p	X
fnp-3453	242	14	<	<	X
fnp-3453	242	15	0.1	0.1	NUM
fnp-3453	242	16	.	.	PUNCT
fnp-3453	243	1	go	go	VERB
fnp-3453	243	2	analysis	analysis	NOUN
fnp-3453	243	3	was	be	AUX
fnp-3453	243	4	performed	perform	VERB
fnp-3453	243	5	using	use	VERB
fnp-3453	243	6	any	any	DET
fnp-3453	243	7	gene	gene	NOUN
fnp-3453	243	8	that	that	PRON
fnp-3453	243	9	met	meet	VERB
fnp-3453	243	10	nominal	nominal	ADJ
fnp-3453	243	11	p	p	X
fnp-3453	243	12	<	<	X
fnp-3453	243	13	0.05	0.05	NUM
fnp-3453	243	14	significance	significance	NOUN
fnp-3453	243	15	.	.	PUNCT
fnp-3453	244	1	the	the	DET
fnp-3453	244	2	top	top	ADJ
fnp-3453	244	3	5	5	NUM
fnp-3453	244	4	positive	positive	ADJ
fnp-3453	244	5	and	and	CCONJ
fnp-3453	244	6	negative	negative	ADJ
fnp-3453	244	7	genes	gene	NOUN
fnp-3453	244	8	for	for	ADP
fnp-3453	244	9	each	each	DET
fnp-3453	244	10	group	group	NOUN
fnp-3453	244	11	were	be	AUX
fnp-3453	244	12	annotated	annotate	VERB
fnp-3453	244	13	.	.	PUNCT
fnp-3453	245	1	[	[	X
fnp-3453	245	2	please	please	INTJ
fnp-3453	245	3	click	click	VERB
fnp-3453	245	4	on	on	ADP
fnp-3453	245	5	the	the	DET
fnp-3453	245	6	figure	figure	NOUN
fnp-3453	245	7	to	to	PART
fnp-3453	245	8	download	download	VERB
fnp-3453	245	9	a	a	DET
fnp-3453	245	10	high	high	ADJ
fnp-3453	245	11	-	-	PUNCT
fnp-3453	245	12	resolution	resolution	NOUN
fnp-3453	245	13	version	version	NOUN
fnp-3453	245	14	]	]	PUNCT
fnp-3453	245	15	discussion	discussion	NOUN
fnp-3453	245	16	building	building	NOUN
fnp-3453	245	17	on	on	ADP
fnp-3453	245	18	previous	previous	ADJ
fnp-3453	245	19	work	work	NOUN
fnp-3453	245	20	suggesting	suggest	VERB
fnp-3453	245	21	that	that	SCONJ
fnp-3453	245	22	altered	alter	VERB
fnp-3453	245	23	neuroinflammation	neuroinflammation	NOUN
fnp-3453	245	24	is	be	AUX
fnp-3453	245	25	an	an	DET
fnp-3453	245	26	early	early	ADJ
fnp-3453	245	27	event	event	NOUN
fnp-3453	245	28	in	in	ADP
fnp-3453	245	29	cte	cte	NOUN
fnp-3453	245	30	,	,	PUNCT
fnp-3453	245	31	here	here	ADV
fnp-3453	245	32	we	we	PRON
fnp-3453	245	33	have	have	AUX
fnp-3453	245	34	demonstrated	demonstrate	VERB
fnp-3453	245	35	that	that	SCONJ
fnp-3453	245	36	there	there	PRON
fnp-3453	245	37	is	be	VERB
fnp-3453	245	38	a	a	DET
fnp-3453	245	39	complex	complex	ADJ
fnp-3453	245	40	inflammatory	inflammatory	ADJ
fnp-3453	245	41	response	response	NOUN
fnp-3453	245	42	encompassing	encompass	VERB
fnp-3453	245	43	several	several	ADJ
fnp-3453	245	44	unique	unique	ADJ
fnp-3453	245	45	biological	biological	ADJ
fnp-3453	245	46	categories	category	NOUN
fnp-3453	245	47	occurring	occur	VERB
fnp-3453	245	48	specifically	specifically	ADV
fnp-3453	245	49	in	in	ADP
fnp-3453	245	50	the	the	DET
fnp-3453	245	51	sulcus	sulcus	NOUN
fnp-3453	245	52	and	and	CCONJ
fnp-3453	245	53	might	might	AUX
fnp-3453	245	54	be	be	AUX
fnp-3453	245	55	directly	directly	ADV
fnp-3453	245	56	related	relate	VERB
fnp-3453	245	57	to	to	ADP
fnp-3453	245	58	cte	cte	VERB
fnp-3453	245	59	pathogenesis	pathogenesis	NOUN
fnp-3453	245	60	.	.	PUNCT
fnp-3453	246	1	when	when	SCONJ
fnp-3453	246	2	comparing	compare	VERB
fnp-3453	246	3	the	the	DET
fnp-3453	246	4	sulcus	sulcus	NOUN
fnp-3453	246	5	to	to	ADP
fnp-3453	246	6	the	the	DET
fnp-3453	246	7	neighboring	neighbor	VERB
fnp-3453	246	8	gyral	gyral	ADJ
fnp-3453	246	9	crest	crest	NOUN
fnp-3453	246	10	we	we	PRON
fnp-3453	246	11	observed	observe	VERB
fnp-3453	246	12	that	that	SCONJ
fnp-3453	246	13	although	although	SCONJ
fnp-3453	246	14	there	there	PRON
fnp-3453	246	15	was	be	VERB
fnp-3453	246	16	pronounced	pronounce	VERB
fnp-3453	246	17	gene	gene	NOUN
fnp-3453	246	18	expression	expression	NOUN
fnp-3453	246	19	related	relate	VERB
fnp-3453	246	20	changes	change	NOUN
fnp-3453	246	21	present	present	ADJ
fnp-3453	246	22	in	in	ADP
fnp-3453	246	23	both	both	DET
fnp-3453	246	24	regions	region	NOUN
fnp-3453	246	25	,	,	PUNCT
fnp-3453	246	26	there	there	PRON
fnp-3453	246	27	was	be	VERB
fnp-3453	246	28	a	a	DET
fnp-3453	246	29	further	far	ADV
fnp-3453	246	30	amplified	amplify	VERB
fnp-3453	246	31	and	and	CCONJ
fnp-3453	246	32	specific	specific	ADJ
fnp-3453	246	33	sulcal	sulcal	ADJ
fnp-3453	246	34	alterations	alteration	NOUN
fnp-3453	246	35	that	that	PRON
fnp-3453	246	36	might	might	AUX
fnp-3453	246	37	be	be	AUX
fnp-3453	246	38	related	relate	VERB
fnp-3453	246	39	to	to	PART
fnp-3453	246	40	head	head	VERB
fnp-3453	246	41	trauma	trauma	NOUN
fnp-3453	246	42	and	and	CCONJ
fnp-3453	246	43	cte	cte	NOUN
fnp-3453	246	44	pathogenesis	pathogenesis	NOUN
fnp-3453	246	45	.	.	PUNCT
fnp-3453	247	1	when	when	SCONJ
fnp-3453	247	2	comparing	compare	VERB
fnp-3453	247	3	what	what	PRON
fnp-3453	247	4	genes	gene	NOUN
fnp-3453	247	5	and	and	CCONJ
fnp-3453	247	6	biological	biological	ADJ
fnp-3453	247	7	processes	process	NOUN
fnp-3453	247	8	were	be	AUX
fnp-3453	247	9	altered	alter	VERB
fnp-3453	247	10	in	in	ADP
fnp-3453	247	11	the	the	DET
fnp-3453	247	12	sulcus	sulcus	NOUN
fnp-3453	247	13	compared	compare	VERB
fnp-3453	247	14	to	to	ADP
fnp-3453	247	15	the	the	DET
fnp-3453	247	16	crest	crest	NOUN
fnp-3453	247	17	,	,	PUNCT
fnp-3453	247	18	several	several	ADJ
fnp-3453	247	19	higher	high	ADJ
fnp-3453	247	20	order	order	NOUN
fnp-3453	247	21	biological	biological	ADJ
fnp-3453	247	22	categories	category	NOUN
fnp-3453	247	23	were	be	AUX
fnp-3453	247	24	observed	observe	VERB
fnp-3453	247	25	to	to	PART
fnp-3453	247	26	consistently	consistently	ADV
fnp-3453	247	27	change	change	VERB
fnp-3453	247	28	across	across	ADP
fnp-3453	247	29	control	control	NOUN
fnp-3453	247	30	,	,	PUNCT
fnp-3453	247	31	rhi	rhi	PROPN
fnp-3453	247	32	,	,	PUNCT
fnp-3453	247	33	and	and	CCONJ
fnp-3453	247	34	cte	cte	PROPN
fnp-3453	247	35	.	.	PROPN
fnp-3453	248	1	immune	immune	PROPN
fnp-3453	248	2	,	,	PUNCT
fnp-3453	248	3	transcriptional	transcriptional	ADJ
fnp-3453	248	4	/	/	SYM
fnp-3453	248	5	translation	translation	NOUN
fnp-3453	248	6	,	,	PUNCT
fnp-3453	248	7	ecm	ecm	NOUN
fnp-3453	248	8	,	,	PUNCT
fnp-3453	248	9	and	and	CCONJ
fnp-3453	248	10	vascular	vascular	ADJ
fnp-3453	248	11	categories	category	NOUN
fnp-3453	248	12	all	all	PRON
fnp-3453	248	13	were	be	AUX
fnp-3453	248	14	positively	positively	ADV
fnp-3453	248	15	enriched	enrich	VERB
fnp-3453	248	16	in	in	ADP
fnp-3453	248	17	the	the	DET
fnp-3453	248	18	sulcus	sulcus	NOUN
fnp-3453	248	19	while	while	SCONJ
fnp-3453	248	20	neuronal	neuronal	ADJ
fnp-3453	248	21	and	and	CCONJ
fnp-3453	248	22	endocytosis	endocytosis	NOUN
fnp-3453	248	23	/	/	SYM
fnp-3453	248	24	exocytosis	exocytosis	NOUN
fnp-3453	248	25	processes	process	NOUN
fnp-3453	248	26	were	be	AUX
fnp-3453	248	27	commonly	commonly	ADV
fnp-3453	248	28	negatively	negatively	ADV
fnp-3453	248	29	enriched	enrich	VERB
fnp-3453	248	30	in	in	ADP
fnp-3453	248	31	the	the	DET
fnp-3453	248	32	sulcus	sulcus	NOUN
fnp-3453	248	33	.	.	PUNCT
fnp-3453	249	1	these	these	DET
fnp-3453	249	2	findings	finding	NOUN
fnp-3453	249	3	demonstrate	demonstrate	VERB
fnp-3453	249	4	that	that	SCONJ
fnp-3453	249	5	even	even	ADV
fnp-3453	249	6	in	in	ADP
fnp-3453	249	7	the	the	DET
fnp-3453	249	8	absence	absence	NOUN
fnp-3453	249	9	of	of	ADP
fnp-3453	249	10	rhi	rhi	PROPN
fnp-3453	249	11	exposure	exposure	NOUN
fnp-3453	249	12	or	or	CCONJ
fnp-3453	249	13	cte	cte	PROPN
fnp-3453	249	14	pathology	pathology	PROPN
fnp-3453	249	15	,	,	PUNCT
fnp-3453	249	16	the	the	DET
fnp-3453	249	17	sulcus	sulcus	NOUN
fnp-3453	249	18	had	have	VERB
fnp-3453	249	19	a	a	DET
fnp-3453	249	20	unique	unique	ADJ
fnp-3453	249	21	expression	expression	NOUN
fnp-3453	249	22	pattern	pattern	NOUN
fnp-3453	249	23	compared	compare	VERB
fnp-3453	249	24	to	to	ADP
fnp-3453	249	25	the	the	DET
fnp-3453	249	26	gryal	gryal	ADJ
fnp-3453	249	27	crest	crest	NOUN
fnp-3453	249	28	and	and	CCONJ
fnp-3453	249	29	might	might	AUX
fnp-3453	249	30	help	help	VERB
fnp-3453	249	31	partly	partly	ADV
fnp-3453	249	32	explain	explain	VERB
fnp-3453	249	33	the	the	DET
fnp-3453	249	34	susceptibility	susceptibility	NOUN
fnp-3453	249	35	to	to	PART
fnp-3453	249	36	head	head	VERB
fnp-3453	249	37	trauma	trauma	NOUN
fnp-3453	249	38	and	and	CCONJ
fnp-3453	249	39	tau	tau	PROPN
fnp-3453	249	40	deposition	deposition	NOUN
fnp-3453	249	41	.	.	PUNCT
fnp-3453	250	1	when	when	SCONJ
fnp-3453	250	2	examining	examine	VERB
fnp-3453	250	3	how	how	SCONJ
fnp-3453	250	4	the	the	DET
fnp-3453	250	5	sulcal	sulcal	ADJ
fnp-3453	250	6	specific	specific	ADJ
fnp-3453	250	7	alterations	alteration	NOUN
fnp-3453	250	8	might	might	AUX
fnp-3453	250	9	change	change	VERB
fnp-3453	250	10	in	in	ADP
fnp-3453	250	11	response	response	NOUN
fnp-3453	250	12	to	to	PART
fnp-3453	250	13	trauma	trauma	VERB
fnp-3453	250	14	and	and	CCONJ
fnp-3453	250	15	disease	disease	NOUN
fnp-3453	250	16	,	,	PUNCT
fnp-3453	250	17	in	in	ADP
fnp-3453	250	18	the	the	DET
fnp-3453	250	19	rhi	rhi	PROPN
fnp-3453	250	20	and	and	CCONJ
fnp-3453	250	21	cte	cte	PROPN
fnp-3453	250	22	group	group	NOUN
fnp-3453	250	23	there	there	PRON
fnp-3453	250	24	was	be	VERB
fnp-3453	250	25	a	a	DET
fnp-3453	250	26	complex	complex	ADJ
fnp-3453	250	27	mixed	mixed	ADJ
fnp-3453	250	28	increase	increase	NOUN
fnp-3453	250	29	and	and	CCONJ
fnp-3453	250	30	decrease	decrease	NOUN
fnp-3453	250	31	of	of	ADP
fnp-3453	250	32	inflammatory	inflammatory	ADJ
fnp-3453	250	33	processes	process	NOUN
fnp-3453	250	34	such	such	ADJ
fnp-3453	250	35	as	as	ADP
fnp-3453	250	36	astrocyte	astrocyte	NOUN
fnp-3453	250	37	development	development	NOUN
fnp-3453	250	38	,	,	PUNCT
fnp-3453	250	39	scavenger	scavenger	NOUN
fnp-3453	250	40	receptor	receptor	NOUN
fnp-3453	250	41	activity	activity	NOUN
fnp-3453	250	42	,	,	PUNCT
fnp-3453	250	43	regulation	regulation	NOUN
fnp-3453	250	44	of	of	ADP
fnp-3453	250	45	immune	immune	ADJ
fnp-3453	250	46	response	response	NOUN
fnp-3453	250	47	,	,	PUNCT
fnp-3453	250	48	leukocyte	leukocyte	NOUN
fnp-3453	250	49	migration	migration	NOUN
fnp-3453	250	50	,	,	PUNCT
fnp-3453	250	51	and	and	CCONJ
fnp-3453	250	52	antigen	antigen	NOUN
fnp-3453	250	53	processing	processing	NOUN
fnp-3453	250	54	compared	compare	VERB
fnp-3453	250	55	to	to	ADP
fnp-3453	250	56	the	the	DET
fnp-3453	250	57	controls	control	NOUN
fnp-3453	250	58	.	.	PUNCT
fnp-3453	251	1	additionally	additionally	ADV
fnp-3453	251	2	,	,	PUNCT
fnp-3453	251	3	neuronal	neuronal	ADJ
fnp-3453	251	4	processes	process	NOUN
fnp-3453	251	5	were	be	AUX
fnp-3453	251	6	elevated	elevate	VERB
fnp-3453	251	7	after	after	ADP
fnp-3453	251	8	rhi	rhi	PROPN
fnp-3453	251	9	and	and	CCONJ
fnp-3453	251	10	during	during	ADP
fnp-3453	251	11	cte	cte	PROPN
fnp-3453	251	12	relative	relative	ADJ
fnp-3453	251	13	to	to	ADP
fnp-3453	251	14	control	control	NOUN
fnp-3453	251	15	cases	case	NOUN
fnp-3453	251	16	,	,	PUNCT
fnp-3453	251	17	possibly	possibly	ADV
fnp-3453	251	18	suggesting	suggest	VERB
fnp-3453	251	19	injured	injure	VERB
fnp-3453	251	20	neurons	neuron	NOUN
fnp-3453	251	21	might	might	AUX
fnp-3453	251	22	induce	induce	VERB
fnp-3453	251	23	compensatory	compensatory	ADJ
fnp-3453	251	24	mechanisms	mechanism	NOUN
fnp-3453	251	25	in	in	ADP
fnp-3453	251	26	efforts	effort	NOUN
fnp-3453	251	27	to	to	PART
fnp-3453	251	28	mitigate	mitigate	VERB
fnp-3453	251	29	rhi	rhi	PROPN
fnp-3453	251	30	induced	induced	ADJ
fnp-3453	251	31	damage	damage	NOUN
fnp-3453	251	32	.	.	PUNCT
fnp-3453	252	1	these	these	DET
fnp-3453	252	2	complex	complex	ADJ
fnp-3453	252	3	alterations	alteration	NOUN
fnp-3453	252	4	could	could	AUX
fnp-3453	252	5	also	also	ADV
fnp-3453	252	6	be	be	AUX
fnp-3453	252	7	observed	observe	VERB
fnp-3453	252	8	in	in	ADP
fnp-3453	252	9	transcriptional	transcriptional	ADJ
fnp-3453	252	10	/	/	SYM
fnp-3453	252	11	translational	translational	ADJ
fnp-3453	252	12	,	,	PUNCT
fnp-3453	252	13	cytoskeletal	cytoskeletal	ADJ
fnp-3453	252	14	,	,	PUNCT
fnp-3453	252	15	ecm	ecm	NOUN
fnp-3453	252	16	,	,	PUNCT
fnp-3453	252	17	mitochondria	mitochondria	NOUN
fnp-3453	252	18	/	/	SYM
fnp-3453	252	19	metabolism	metabolism	NOUN
fnp-3453	252	20	,	,	PUNCT
fnp-3453	252	21	signaling	signaling	ADJ
fnp-3453	252	22	,	,	PUNCT
fnp-3453	252	23	vascular	vascular	ADJ
fnp-3453	252	24	,	,	PUNCT
fnp-3453	252	25	endocytosis	endocytosis	NOUN
fnp-3453	252	26	/	/	SYM
fnp-3453	252	27	exocytosis	exocytosis	NOUN
fnp-3453	252	28	,	,	PUNCT
fnp-3453	252	29	and	and	CCONJ
fnp-3453	252	30	protein	protein	NOUN
fnp-3453	252	31	processing	processing	NOUN
fnp-3453	252	32	processes	process	NOUN
fnp-3453	252	33	as	as	ADV
fnp-3453	252	34	well	well	ADV
fnp-3453	252	35	.	.	PUNCT
fnp-3453	253	1	finally	finally	ADV
fnp-3453	253	2	,	,	PUNCT
fnp-3453	253	3	we	we	PRON
fnp-3453	253	4	observed	observe	VERB
fnp-3453	253	5	that	that	SCONJ
fnp-3453	253	6	each	each	PRON
fnp-3453	253	7	of	of	ADP
fnp-3453	253	8	the	the	DET
fnp-3453	253	9	three	three	NUM
fnp-3453	253	10	groups	group	NOUN
fnp-3453	253	11	had	have	VERB
fnp-3453	253	12	a	a	DET
fnp-3453	253	13	set	set	NOUN
fnp-3453	253	14	of	of	ADP
fnp-3453	253	15	genes	gene	NOUN
fnp-3453	253	16	and	and	CCONJ
fnp-3453	253	17	processes	process	NOUN
fnp-3453	253	18	that	that	PRON
fnp-3453	253	19	were	be	AUX
fnp-3453	253	20	uniquely	uniquely	ADV
fnp-3453	253	21	altered	alter	VERB
fnp-3453	253	22	in	in	ADP
fnp-3453	253	23	the	the	DET
fnp-3453	253	24	sulcus	sulcus	NOUN
fnp-3453	253	25	.	.	PUNCT
fnp-3453	254	1	go	go	VERB
fnp-3453	254	2	analysis	analysis	NOUN
fnp-3453	254	3	demonstrated	demonstrate	VERB
fnp-3453	254	4	that	that	SCONJ
fnp-3453	254	5	within	within	ADP
fnp-3453	254	6	the	the	DET
fnp-3453	254	7	control	control	NOUN
fnp-3453	254	8	group	group	NOUN
fnp-3453	254	9	,	,	PUNCT
fnp-3453	254	10	specifically	specifically	ADV
fnp-3453	254	11	altered	alter	VERB
fnp-3453	254	12	genes	gene	NOUN
fnp-3453	254	13	were	be	AUX
fnp-3453	254	14	related	relate	VERB
fnp-3453	254	15	to	to	ADP
fnp-3453	254	16	development	development	NOUN
fnp-3453	254	17	and	and	CCONJ
fnp-3453	254	18	homeostasis	homeostasis	NOUN
fnp-3453	254	19	;	;	PUNCT
fnp-3453	254	20	within	within	ADP
fnp-3453	254	21	rhi	rhi	PROPN
fnp-3453	254	22	,	,	PUNCT
fnp-3453	254	23	altered	alter	VERB
fnp-3453	254	24	genes	gene	NOUN
fnp-3453	254	25	were	be	AUX
fnp-3453	254	26	metabolic	metabolic	NOUN
fnp-3453	254	27	and	and	CCONJ
fnp-3453	254	28	mitochondria	mitochondria	NOUN
fnp-3453	254	29	related	relate	VERB
fnp-3453	254	30	;	;	PUNCT
fnp-3453	254	31	and	and	CCONJ
fnp-3453	254	32	within	within	ADP
fnp-3453	254	33	cte	cte	NOUN
fnp-3453	254	34	,	,	PUNCT
fnp-3453	254	35	altered	alter	VERB
fnp-3453	254	36	genes	gene	NOUN
fnp-3453	254	37	were	be	AUX
fnp-3453	254	38	immune	immune	ADJ
fnp-3453	254	39	and	and	CCONJ
fnp-3453	254	40	inflammation	inflammation	NOUN
fnp-3453	254	41	related	relate	VERB
fnp-3453	254	42	.	.	PUNCT
fnp-3453	255	1	overall	overall	ADV
fnp-3453	255	2	,	,	PUNCT
fnp-3453	255	3	we	we	PRON
fnp-3453	255	4	have	have	AUX
fnp-3453	255	5	built	build	VERB
fnp-3453	255	6	on	on	ADP
fnp-3453	255	7	previous	previous	ADJ
fnp-3453	255	8	work	work	NOUN
fnp-3453	255	9	and	and	CCONJ
fnp-3453	255	10	expanded	expand	VERB
fnp-3453	255	11	our	our	PRON
fnp-3453	255	12	understanding	understanding	NOUN
fnp-3453	255	13	of	of	ADP
fnp-3453	255	14	the	the	DET
fnp-3453	255	15	complex	complex	ADJ
fnp-3453	255	16	neurodegenerative	neurodegenerative	ADJ
fnp-3453	255	17	response	response	NOUN
fnp-3453	255	18	that	that	PRON
fnp-3453	255	19	occurs	occur	VERB
fnp-3453	255	20	after	after	ADP
fnp-3453	255	21	rhi	rhi	PROPN
fnp-3453	255	22	and	and	CCONJ
fnp-3453	255	23	during	during	ADP
fnp-3453	255	24	cte	cte	NOUN
fnp-3453	255	25	.	.	PUNCT
fnp-3453	256	1	since	since	SCONJ
fnp-3453	256	2	p	p	PROPN
fnp-3453	256	3	-	-	PUNCT
fnp-3453	256	4	tau	tau	NOUN
fnp-3453	256	5	deposition	deposition	NOUN
fnp-3453	256	6	in	in	ADP
fnp-3453	256	7	the	the	DET
fnp-3453	256	8	crest	crest	NOUN
fnp-3453	256	9	is	be	AUX
fnp-3453	256	10	less	less	ADV
fnp-3453	256	11	likely	likely	ADJ
fnp-3453	256	12	in	in	ADP
fnp-3453	256	13	early	early	ADJ
fnp-3453	256	14	cte	cte	NOUN
fnp-3453	256	15	,	,	PUNCT
fnp-3453	256	16	genes	gene	NOUN
fnp-3453	256	17	that	that	PRON
fnp-3453	256	18	were	be	AUX
fnp-3453	256	19	found	find	VERB
fnp-3453	256	20	to	to	PART
fnp-3453	256	21	be	be	AUX
fnp-3453	256	22	differentially	differentially	ADV
fnp-3453	256	23	expressed	express	VERB
fnp-3453	256	24	in	in	ADP
fnp-3453	256	25	both	both	CCONJ
fnp-3453	256	26	the	the	DET
fnp-3453	256	27	sulcus	sulcus	NOUN
fnp-3453	256	28	and	and	CCONJ
fnp-3453	256	29	the	the	DET
fnp-3453	256	30	crest	crest	NOUN
fnp-3453	256	31	are	be	AUX
fnp-3453	256	32	possibly	possibly	ADV
fnp-3453	256	33	less	less	ADV
fnp-3453	256	34	specific	specific	ADJ
fnp-3453	256	35	to	to	PART
fnp-3453	256	36	cte	cte	VERB
fnp-3453	256	37	sulcal	sulcal	ADJ
fnp-3453	256	38	p	p	PROPN
fnp-3453	256	39	-	-	PUNCT
fnp-3453	256	40	tau	tau	NOUN
fnp-3453	256	41	deposition	deposition	NOUN
fnp-3453	256	42	and	and	CCONJ
fnp-3453	256	43	more	more	ADV
fnp-3453	256	44	related	related	ADJ
fnp-3453	256	45	to	to	ADP
fnp-3453	256	46	a	a	DET
fnp-3453	256	47	general	general	ADJ
fnp-3453	256	48	response	response	NOUN
fnp-3453	256	49	to	to	PART
fnp-3453	256	50	head	head	VERB
fnp-3453	256	51	trauma	trauma	NOUN
fnp-3453	256	52	.	.	PUNCT
fnp-3453	257	1	consistent	consistent	ADJ
fnp-3453	257	2	with	with	ADP
fnp-3453	257	3	previous	previous	ADJ
fnp-3453	257	4	reports	report	NOUN
fnp-3453	257	5	on	on	ADP
fnp-3453	257	6	how	how	SCONJ
fnp-3453	257	7	repetitive	repetitive	ADJ
fnp-3453	257	8	head	head	NOUN
fnp-3453	257	9	trauma	trauma	NOUN
fnp-3453	257	10	affects	affect	VERB
fnp-3453	257	11	the	the	DET
fnp-3453	257	12	cns	cns	NOUN
fnp-3453	257	13	,	,	PUNCT
fnp-3453	257	14	the	the	DET
fnp-3453	257	15	most	most	ADV
fnp-3453	257	16	common	common	ADJ
fnp-3453	257	17	genes	gene	NOUN
fnp-3453	257	18	that	that	PRON
fnp-3453	257	19	were	be	AUX
fnp-3453	257	20	altered	alter	VERB
fnp-3453	257	21	in	in	ADP
fnp-3453	257	22	both	both	CCONJ
fnp-3453	257	23	the	the	DET
fnp-3453	257	24	sulcus	sulcus	NOUN
fnp-3453	257	25	and	and	CCONJ
fnp-3453	257	26	crest	crest	NOUN
fnp-3453	257	27	in	in	ADP
fnp-3453	257	28	cte	cte	PROPN
fnp-3453	257	29	were	be	AUX
fnp-3453	257	30	immune	immune	ADJ
fnp-3453	257	31	and	and	CCONJ
fnp-3453	257	32	inflammatory	inflammatory	ADJ
fnp-3453	257	33	related	relate	VERB
fnp-3453	257	34	(	(	PUNCT
fnp-3453	257	35	figures	figure	NOUN
fnp-3453	257	36	2&3	2&3	NUM
fnp-3453	257	37	)	)	PUNCT
fnp-3453	257	38	.	.	PUNCT
fnp-3453	258	1	we	we	PRON
fnp-3453	258	2	observed	observe	VERB
fnp-3453	258	3	that	that	SCONJ
fnp-3453	258	4	there	there	PRON
fnp-3453	258	5	was	be	VERB
fnp-3453	258	6	a	a	DET
fnp-3453	258	7	significant	significant	ADJ
fnp-3453	258	8	upregulation	upregulation	NOUN
fnp-3453	258	9	in	in	ADP
fnp-3453	258	10	complement	complement	NOUN
fnp-3453	258	11	genes	gene	NOUN
fnp-3453	258	12	c4a	c4a	ADJ
fnp-3453	258	13	and	and	CCONJ
fnp-3453	258	14	c4b	c4b	PROPN
fnp-3453	258	15	suggesting	suggest	VERB
fnp-3453	258	16	a	a	DET
fnp-3453	258	17	persistent	persistent	ADJ
fnp-3453	258	18	innate	innate	ADJ
fnp-3453	258	19	immune	immune	ADJ
fnp-3453	258	20	response	response	NOUN
fnp-3453	258	21	and	and	CCONJ
fnp-3453	258	22	activation	activation	NOUN
fnp-3453	258	23	of	of	ADP
fnp-3453	258	24	the	the	DET
fnp-3453	258	25	complement	complement	NOUN
fnp-3453	258	26	cascade	cascade	NOUN
fnp-3453	258	27	was	be	AUX
fnp-3453	258	28	present	present	ADJ
fnp-3453	258	29	in	in	ADP
fnp-3453	258	30	the	the	DET
fnp-3453	258	31	frontal	frontal	ADJ
fnp-3453	258	32	cortex	cortex	NOUN
fnp-3453	258	33	.	.	PUNCT
fnp-3453	259	1	complement	complement	NOUN
fnp-3453	259	2	has	have	VERB
fnp-3453	259	3	a	a	DET
fnp-3453	259	4	wide	wide	ADJ
fnp-3453	259	5	variety	variety	NOUN
fnp-3453	259	6	of	of	ADP
fnp-3453	259	7	functions	function	NOUN
fnp-3453	259	8	,	,	PUNCT
fnp-3453	259	9	but	but	CCONJ
fnp-3453	259	10	in	in	ADP
fnp-3453	259	11	the	the	DET
fnp-3453	259	12	context	context	NOUN
fnp-3453	259	13	of	of	ADP
fnp-3453	259	14	neurodegeneration	neurodegeneration	NOUN
fnp-3453	259	15	,	,	PUNCT
fnp-3453	259	16	it	it	PRON
fnp-3453	259	17	has	have	AUX
fnp-3453	259	18	been	be	AUX
fnp-3453	259	19	associated	associate	VERB
fnp-3453	259	20	with	with	ADP
fnp-3453	259	21	increased	increase	VERB
fnp-3453	259	22	synaptic	synaptic	ADJ
fnp-3453	259	23	pruning	pruning	NOUN
fnp-3453	259	24	and	and	CCONJ
fnp-3453	259	25	synaptic	synaptic	ADJ
fnp-3453	259	26	loss	loss	NOUN
fnp-3453	259	27	[	[	X
fnp-3453	259	28	27	27	NUM
fnp-3453	259	29	]	]	PUNCT
fnp-3453	259	30	.	.	PUNCT
fnp-3453	260	1	it	it	PRON
fnp-3453	260	2	is	be	AUX
fnp-3453	260	3	possible	possible	ADJ
fnp-3453	260	4	the	the	DET
fnp-3453	260	5	c4	c4	NOUN
fnp-3453	260	6	activity	activity	NOUN
fnp-3453	260	7	is	be	AUX
fnp-3453	260	8	related	relate	VERB
fnp-3453	260	9	to	to	ADP
fnp-3453	260	10	the	the	DET
fnp-3453	260	11	psd-95	psd-95	CCONJ
fnp-3453	260	12	synaptic	synaptic	ADJ
fnp-3453	260	13	protein	protein	NOUN
fnp-3453	260	14	loss	loss	NOUN
fnp-3453	260	15	that	that	PRON
fnp-3453	260	16	has	have	AUX
fnp-3453	260	17	been	be	AUX
fnp-3453	260	18	reported	report	VERB
fnp-3453	260	19	in	in	ADP
fnp-3453	260	20	previous	previous	ADJ
fnp-3453	260	21	cte	cte	NOUN
fnp-3453	260	22	studies	study	NOUN
fnp-3453	260	23	[	[	X
fnp-3453	260	24	5	5	NUM
fnp-3453	260	25	]	]	PUNCT
fnp-3453	260	26	.	.	PUNCT
fnp-3453	261	1	c4	c4	NOUN
fnp-3453	261	2	has	have	AUX
fnp-3453	261	3	been	be	AUX
fnp-3453	261	4	suggested	suggest	VERB
fnp-3453	261	5	to	to	PART
fnp-3453	261	6	play	play	VERB
fnp-3453	261	7	a	a	DET
fnp-3453	261	8	role	role	NOUN
fnp-3453	261	9	in	in	ADP
fnp-3453	261	10	synaptic	synaptic	ADJ
fnp-3453	261	11	pruning	pruning	NOUN
fnp-3453	261	12	in	in	ADP
fnp-3453	261	13	schizophrenia	schizophrenia	NOUN
fnp-3453	262	1	[	[	X
fnp-3453	262	2	28	28	NUM
fnp-3453	262	3	]	]	PUNCT
fnp-3453	262	4	,	,	PUNCT
fnp-3453	262	5	and	and	CCONJ
fnp-3453	262	6	c4	c4	NOUN
fnp-3453	262	7	gene	gene	NOUN
fnp-3453	262	8	expression	expression	NOUN
fnp-3453	262	9	and	and	CCONJ
fnp-3453	262	10	protein	protein	NOUN
fnp-3453	262	11	levels	level	NOUN
fnp-3453	262	12	have	have	AUX
fnp-3453	262	13	recently	recently	ADV
fnp-3453	262	14	been	be	AUX
fnp-3453	262	15	linked	link	VERB
fnp-3453	262	16	to	to	ADP
fnp-3453	262	17	tau	tau	PROPN
fnp-3453	262	18	phosphatases	phosphatase	NOUN
fnp-3453	262	19	and	and	CCONJ
fnp-3453	262	20	the	the	DET
fnp-3453	262	21	development	development	NOUN
fnp-3453	262	22	of	of	ADP
fnp-3453	262	23	ad	ad	NOUN
fnp-3453	262	24	suggesting	suggest	VERB
fnp-3453	262	25	a	a	DET
fnp-3453	262	26	possible	possible	ADJ
fnp-3453	262	27	mechanism	mechanism	NOUN
fnp-3453	262	28	in	in	ADP
fnp-3453	262	29	the	the	DET
fnp-3453	262	30	development	development	NOUN
fnp-3453	262	31	of	of	ADP
fnp-3453	262	32	tau	tau	PROPN
fnp-3453	262	33	pathology	pathology	NOUN
fnp-3453	263	1	[	[	X
fnp-3453	263	2	15	15	NUM
fnp-3453	263	3	]	]	PUNCT
fnp-3453	263	4	.	.	PUNCT
fnp-3453	264	1	additionally	additionally	ADV
fnp-3453	264	2	,	,	PUNCT
fnp-3453	264	3	microglia	microglia	ADJ
fnp-3453	264	4	related	relate	VERB
fnp-3453	264	5	genes	gene	NOUN
fnp-3453	264	6	,	,	PUNCT
fnp-3453	264	7	such	such	ADJ
fnp-3453	264	8	as	as	ADP
fnp-3453	264	9	cxcr1	cxcr1	PROPN
fnp-3453	264	10	,	,	PUNCT
fnp-3453	264	11	were	be	AUX
fnp-3453	264	12	elevated	elevate	VERB
fnp-3453	264	13	in	in	ADP
fnp-3453	264	14	cte	cte	NOUN
fnp-3453	264	15	,	,	PUNCT
fnp-3453	264	16	which	which	PRON
fnp-3453	264	17	is	be	AUX
fnp-3453	264	18	in	in	ADP
fnp-3453	264	19	agreement	agreement	NOUN
fnp-3453	264	20	with	with	ADP
fnp-3453	264	21	previous	previous	ADJ
fnp-3453	264	22	studies	study	NOUN
fnp-3453	264	23	examining	examine	VERB
fnp-3453	264	24	microglia	microglia	ADJ
fnp-3453	264	25	related	relate	VERB
fnp-3453	264	26	changes	change	NOUN
fnp-3453	264	27	in	in	ADP
fnp-3453	264	28	cte	cte	NOUN
fnp-3453	264	29	[	[	X
fnp-3453	264	30	4	4	NUM
fnp-3453	264	31	,	,	PUNCT
fnp-3453	264	32	7	7	NUM
fnp-3453	264	33	]	]	PUNCT
fnp-3453	264	34	.	.	PUNCT
fnp-3453	265	1	astrocytic	astrocytic	ADJ
fnp-3453	265	2	genes	gene	NOUN
fnp-3453	265	3	,	,	PUNCT
fnp-3453	265	4	gfap	gfap	NOUN
fnp-3453	265	5	and	and	CCONJ
fnp-3453	265	6	aqp1	aqp1	PROPN
fnp-3453	265	7	,	,	PUNCT
fnp-3453	265	8	were	be	AUX
fnp-3453	265	9	also	also	ADV
fnp-3453	265	10	found	find	VERB
fnp-3453	265	11	to	to	PART
fnp-3453	265	12	be	be	AUX
fnp-3453	265	13	increased	increase	VERB
fnp-3453	265	14	in	in	ADP
fnp-3453	265	15	both	both	CCONJ
fnp-3453	265	16	the	the	DET
fnp-3453	265	17	sulcus	sulcus	NOUN
fnp-3453	265	18	and	and	CCONJ
fnp-3453	265	19	crest	crest	NOUN
fnp-3453	265	20	.	.	PUNCT
fnp-3453	266	1	it	it	PRON
fnp-3453	266	2	has	have	AUX
fnp-3453	266	3	been	be	AUX
fnp-3453	266	4	suggested	suggest	VERB
fnp-3453	266	5	that	that	SCONJ
fnp-3453	266	6	there	there	PRON
fnp-3453	266	7	is	be	VERB
fnp-3453	266	8	impairment	impairment	NOUN
fnp-3453	266	9	of	of	ADP
fnp-3453	266	10	aqp4	aqp4	PROPN
fnp-3453	266	11	after	after	ADP
fnp-3453	266	12	trauma	trauma	NOUN
fnp-3453	266	13	,	,	PUNCT
fnp-3453	266	14	and	and	CCONJ
fnp-3453	266	15	it	it	PRON
fnp-3453	266	16	is	be	AUX
fnp-3453	266	17	possible	possible	ADJ
fnp-3453	266	18	that	that	SCONJ
fnp-3453	266	19	aqp1	aqp1	PROPN
fnp-3453	266	20	was	be	AUX
fnp-3453	266	21	upregulated	upregulate	VERB
fnp-3453	266	22	in	in	ADP
fnp-3453	266	23	compensation	compensation	NOUN
fnp-3453	266	24	[	[	X
fnp-3453	266	25	31	31	NUM
fnp-3453	266	26	]	]	PUNCT
fnp-3453	266	27	.	.	PUNCT
fnp-3453	267	1	interestingly	interestingly	ADV
fnp-3453	267	2	,	,	PUNCT
fnp-3453	267	3	there	there	PRON
fnp-3453	267	4	also	also	ADV
fnp-3453	267	5	appeared	appear	VERB
fnp-3453	267	6	to	to	PART
fnp-3453	267	7	be	be	AUX
fnp-3453	267	8	a	a	DET
fnp-3453	267	9	significant	significant	ADJ
fnp-3453	267	10	neutrophil	neutrophil	ADJ
fnp-3453	267	11	response	response	NOUN
fnp-3453	267	12	found	find	VERB
fnp-3453	267	13	across	across	ADP
fnp-3453	267	14	the	the	DET
fnp-3453	267	15	sulcus	sulcus	NOUN
fnp-3453	267	16	and	and	CCONJ
fnp-3453	267	17	the	the	DET
fnp-3453	267	18	crest	crest	NOUN
fnp-3453	267	19	.	.	PUNCT
fnp-3453	268	1	several	several	ADJ
fnp-3453	268	2	neutrophil	neutrophil	ADJ
fnp-3453	268	3	related	relate	VERB
fnp-3453	268	4	genes	gene	NOUN
fnp-3453	268	5	such	such	ADJ
fnp-3453	268	6	as	as	ADP
fnp-3453	268	7	cd177	cd177	PROPN
fnp-3453	268	8	,	,	PUNCT
fnp-3453	268	9	s100a8	s100a8	PROPN
fnp-3453	268	10	,	,	PUNCT
fnp-3453	268	11	s100a9	s100a9	PROPN
fnp-3453	268	12	,	,	PUNCT
fnp-3453	268	13	bpi	bpi	PROPN
fnp-3453	268	14	,	,	PUNCT
fnp-3453	268	15	and	and	CCONJ
fnp-3453	268	16	lcn2	lcn2	PROPN
fnp-3453	268	17	,	,	PUNCT
fnp-3453	268	18	and	and	CCONJ
fnp-3453	268	19	multiple	multiple	ADJ
fnp-3453	268	20	neutrophil	neutrophil	ADJ
fnp-3453	268	21	gsea	gsea	NOUN
fnp-3453	268	22	processes	process	NOUN
fnp-3453	268	23	were	be	AUX
fnp-3453	268	24	highly	highly	ADV
fnp-3453	268	25	increased	increase	VERB
fnp-3453	268	26	.	.	PUNCT
fnp-3453	269	1	however	however	ADV
fnp-3453	269	2	,	,	PUNCT
fnp-3453	269	3	it	it	PRON
fnp-3453	269	4	is	be	AUX
fnp-3453	269	5	possible	possible	ADJ
fnp-3453	269	6	that	that	SCONJ
fnp-3453	269	7	the	the	DET
fnp-3453	269	8	observed	observe	VERB
fnp-3453	269	9	neutrophil	neutrophil	ADJ
fnp-3453	269	10	response	response	NOUN
fnp-3453	269	11	could	could	AUX
fnp-3453	269	12	be	be	AUX
fnp-3453	269	13	related	relate	VERB
fnp-3453	269	14	to	to	ADP
fnp-3453	269	15	various	various	ADJ
fnp-3453	269	16	causes	cause	NOUN
fnp-3453	269	17	of	of	ADP
fnp-3453	269	18	death	death	NOUN
fnp-3453	269	19	as	as	SCONJ
fnp-3453	269	20	opposed	oppose	VERB
fnp-3453	269	21	to	to	PART
fnp-3453	269	22	contact	contact	VERB
fnp-3453	269	23	sport	sport	NOUN
fnp-3453	269	24	exposure	exposure	NOUN
fnp-3453	269	25	.	.	PUNCT
fnp-3453	270	1	future	future	ADJ
fnp-3453	270	2	work	work	NOUN
fnp-3453	270	3	will	will	AUX
fnp-3453	270	4	be	be	AUX
fnp-3453	270	5	needed	need	VERB
fnp-3453	270	6	to	to	PART
fnp-3453	270	7	closely	closely	ADV
fnp-3453	270	8	examine	examine	VERB
fnp-3453	270	9	if	if	SCONJ
fnp-3453	270	10	neutrophil	neutrophil	ADJ
fnp-3453	270	11	markers	marker	NOUN
fnp-3453	270	12	could	could	AUX
fnp-3453	270	13	be	be	AUX
fnp-3453	270	14	observed	observe	VERB
fnp-3453	270	15	using	use	VERB
fnp-3453	270	16	biomarkers	biomarker	NOUN
fnp-3453	270	17	from	from	ADP
fnp-3453	270	18	living	live	VERB
fnp-3453	270	19	individuals	individual	NOUN
fnp-3453	270	20	to	to	PART
fnp-3453	270	21	better	well	ADV
fnp-3453	270	22	explore	explore	VERB
fnp-3453	270	23	the	the	DET
fnp-3453	270	24	possible	possible	ADJ
fnp-3453	270	25	effects	effect	NOUN
fnp-3453	270	26	of	of	ADP
fnp-3453	270	27	tbi	tbi	NOUN
fnp-3453	270	28	and	and	CCONJ
fnp-3453	270	29	a	a	DET
fnp-3453	270	30	long	long	ADJ
fnp-3453	270	31	-	-	PUNCT
fnp-3453	270	32	term	term	NOUN
fnp-3453	270	33	neutrophil	neutrophil	ADJ
fnp-3453	270	34	response	response	NOUN
fnp-3453	270	35	.	.	PUNCT
fnp-3453	271	1	altogether	altogether	ADV
fnp-3453	271	2	,	,	PUNCT
fnp-3453	271	3	these	these	DET
fnp-3453	271	4	results	result	NOUN
fnp-3453	271	5	demonstrate	demonstrate	VERB
fnp-3453	271	6	that	that	SCONJ
fnp-3453	271	7	there	there	PRON
fnp-3453	271	8	is	be	VERB
fnp-3453	271	9	a	a	DET
fnp-3453	271	10	prominent	prominent	ADJ
fnp-3453	271	11	neuroinflammatory	neuroinflammatory	ADJ
fnp-3453	271	12	response	response	NOUN
fnp-3453	271	13	found	find	VERB
fnp-3453	271	14	in	in	ADP
fnp-3453	271	15	the	the	DET
fnp-3453	271	16	frontal	frontal	ADJ
fnp-3453	271	17	cortex	cortex	NOUN
fnp-3453	271	18	of	of	ADP
fnp-3453	271	19	subjects	subject	NOUN
fnp-3453	271	20	who	who	PRON
fnp-3453	271	21	experience	experience	VERB
fnp-3453	271	22	repetitive	repetitive	ADJ
fnp-3453	271	23	head	head	NOUN
fnp-3453	271	24	trauma	trauma	NOUN
fnp-3453	271	25	.	.	PUNCT
fnp-3453	272	1	however	however	ADV
fnp-3453	272	2	,	,	PUNCT
fnp-3453	272	3	it	it	PRON
fnp-3453	272	4	is	be	AUX
fnp-3453	272	5	likely	likely	ADJ
fnp-3453	272	6	that	that	SCONJ
fnp-3453	272	7	changes	change	NOUN
fnp-3453	272	8	that	that	PRON
fnp-3453	272	9	occur	occur	VERB
fnp-3453	272	10	uniformly	uniformly	ADV
fnp-3453	272	11	in	in	ADP
fnp-3453	272	12	both	both	CCONJ
fnp-3453	272	13	the	the	DET
fnp-3453	272	14	sulcus	sulcus	NOUN
fnp-3453	272	15	and	and	CCONJ
fnp-3453	272	16	crest	crest	NOUN
fnp-3453	272	17	do	do	AUX
fnp-3453	272	18	not	not	PART
fnp-3453	272	19	fully	fully	ADV
fnp-3453	272	20	explain	explain	VERB
fnp-3453	272	21	the	the	DET
fnp-3453	272	22	mechanisms	mechanism	NOUN
fnp-3453	272	23	behind	behind	ADP
fnp-3453	272	24	p	p	PROPN
fnp-3453	272	25	-	-	PUNCT
fnp-3453	272	26	tau	tau	NOUN
fnp-3453	272	27	deposition	deposition	NOUN
fnp-3453	272	28	and	and	CCONJ
fnp-3453	272	29	are	be	AUX
fnp-3453	272	30	only	only	ADV
fnp-3453	272	31	part	part	NOUN
fnp-3453	272	32	of	of	ADP
fnp-3453	272	33	the	the	DET
fnp-3453	272	34	equation	equation	NOUN
fnp-3453	272	35	of	of	ADP
fnp-3453	272	36	cte	cte	NOUN
fnp-3453	272	37	mechanisms	mechanism	NOUN
fnp-3453	272	38	.	.	PUNCT
fnp-3453	273	1	therefore	therefore	ADV
fnp-3453	273	2	,	,	PUNCT
fnp-3453	273	3	it	it	PRON
fnp-3453	273	4	was	be	AUX
fnp-3453	273	5	crucial	crucial	ADJ
fnp-3453	273	6	that	that	SCONJ
fnp-3453	273	7	we	we	PRON
fnp-3453	273	8	expand	expand	VERB
fnp-3453	273	9	our	our	PRON
fnp-3453	273	10	analysis	analysis	NOUN
fnp-3453	273	11	to	to	ADP
fnp-3453	273	12	focusing	focus	VERB
fnp-3453	273	13	on	on	ADP
fnp-3453	273	14	what	what	DET
fnp-3453	273	15	changes	change	NOUN
fnp-3453	273	16	could	could	AUX
fnp-3453	273	17	be	be	AUX
fnp-3453	273	18	observed	observe	VERB
fnp-3453	273	19	uniquely	uniquely	ADV
fnp-3453	273	20	in	in	ADP
fnp-3453	273	21	the	the	DET
fnp-3453	273	22	sulcus	sulcus	NOUN
fnp-3453	273	23	and	and	CCONJ
fnp-3453	273	24	might	might	AUX
fnp-3453	273	25	directly	directly	ADV
fnp-3453	273	26	relate	relate	VERB
fnp-3453	273	27	to	to	ADP
fnp-3453	273	28	cte	cte	VERB
fnp-3453	273	29	pathogenesis	pathogenesis	NOUN
fnp-3453	273	30	.	.	PUNCT
fnp-3453	274	1	interestingly	interestingly	ADV
fnp-3453	274	2	,	,	PUNCT
fnp-3453	274	3	we	we	PRON
fnp-3453	274	4	found	find	VERB
fnp-3453	274	5	that	that	SCONJ
fnp-3453	274	6	multiple	multiple	ADJ
fnp-3453	274	7	factors	factor	NOUN
fnp-3453	274	8	might	might	AUX
fnp-3453	274	9	be	be	AUX
fnp-3453	274	10	contributing	contribute	VERB
fnp-3453	274	11	to	to	ADP
fnp-3453	274	12	sulcal	sulcal	ADJ
fnp-3453	274	13	specific	specific	ADJ
fnp-3453	274	14	alterations	alteration	NOUN
fnp-3453	274	15	.	.	PUNCT
fnp-3453	275	1	our	our	PRON
fnp-3453	275	2	findings	finding	NOUN
fnp-3453	275	3	suggested	suggest	VERB
fnp-3453	275	4	that	that	SCONJ
fnp-3453	275	5	sulcal	sulcal	ADJ
fnp-3453	275	6	specific	specific	ADJ
fnp-3453	275	7	changes	change	NOUN
fnp-3453	275	8	were	be	AUX
fnp-3453	275	9	the	the	DET
fnp-3453	275	10	result	result	NOUN
fnp-3453	275	11	of	of	ADP
fnp-3453	275	12	either	either	DET
fnp-3453	275	13	1	1	NUM
fnp-3453	275	14	)	)	PUNCT
fnp-3453	275	15	anatomy	anatomy	NOUN
fnp-3453	275	16	,	,	PUNCT
fnp-3453	275	17	2	2	NUM
fnp-3453	275	18	)	)	PUNCT
fnp-3453	275	19	repetitive	repetitive	ADJ
fnp-3453	275	20	head	head	NOUN
fnp-3453	275	21	trauma	trauma	NOUN
fnp-3453	275	22	,	,	PUNCT
fnp-3453	275	23	and	and	CCONJ
fnp-3453	275	24	3	3	X
fnp-3453	275	25	)	)	PUNCT
fnp-3453	275	26	p	p	PROPN
fnp-3453	275	27	-	-	PUNCT
fnp-3453	275	28	tau	tau	PROPN
fnp-3453	275	29	pathology	pathology	NOUN
fnp-3453	275	30	.	.	PUNCT
fnp-3453	276	1	although	although	SCONJ
fnp-3453	276	2	the	the	DET
fnp-3453	276	3	sulcus	sulcus	NOUN
fnp-3453	276	4	and	and	CCONJ
fnp-3453	276	5	crest	crest	NOUN
fnp-3453	276	6	are	be	AUX
fnp-3453	276	7	only	only	ADV
fnp-3453	276	8	separated	separate	VERB
fnp-3453	276	9	by	by	ADP
fnp-3453	276	10	centimeters	centimeter	NOUN
fnp-3453	276	11	,	,	PUNCT
fnp-3453	276	12	our	our	PRON
fnp-3453	276	13	current	current	ADJ
fnp-3453	276	14	result	result	NOUN
fnp-3453	276	15	suggest	suggest	VERB
fnp-3453	276	16	that	that	SCONJ
fnp-3453	276	17	each	each	DET
fnp-3453	276	18	region	region	NOUN
fnp-3453	276	19	has	have	VERB
fnp-3453	276	20	a	a	DET
fnp-3453	276	21	unique	unique	ADJ
fnp-3453	276	22	environment	environment	NOUN
fnp-3453	276	23	even	even	ADV
fnp-3453	276	24	in	in	ADP
fnp-3453	276	25	the	the	DET
fnp-3453	276	26	absence	absence	NOUN
fnp-3453	276	27	on	on	ADP
fnp-3453	276	28	trauma	trauma	NOUN
fnp-3453	276	29	or	or	CCONJ
fnp-3453	276	30	neurodegenerative	neurodegenerative	ADJ
fnp-3453	276	31	disease	disease	NOUN
fnp-3453	276	32	.	.	PUNCT
fnp-3453	277	1	when	when	SCONJ
fnp-3453	277	2	comparing	compare	VERB
fnp-3453	277	3	the	the	DET
fnp-3453	277	4	sulcus	sulcus	NOUN
fnp-3453	277	5	to	to	ADP
fnp-3453	277	6	the	the	DET
fnp-3453	277	7	crest	crest	NOUN
fnp-3453	277	8	across	across	ADP
fnp-3453	277	9	each	each	DET
fnp-3453	277	10	group	group	NOUN
fnp-3453	277	11	,	,	PUNCT
fnp-3453	277	12	there	there	PRON
fnp-3453	277	13	was	be	VERB
fnp-3453	277	14	high	high	ADJ
fnp-3453	277	15	agreement	agreement	NOUN
fnp-3453	277	16	in	in	ADP
fnp-3453	277	17	the	the	DET
fnp-3453	277	18	direction	direction	NOUN
fnp-3453	277	19	of	of	ADP
fnp-3453	277	20	effect	effect	NOUN
fnp-3453	277	21	observed	observe	VERB
fnp-3453	277	22	in	in	ADP
fnp-3453	277	23	all	all	DET
fnp-3453	277	24	the	the	DET
fnp-3453	277	25	processes	process	NOUN
fnp-3453	277	26	between	between	ADP
fnp-3453	277	27	control	control	NOUN
fnp-3453	277	28	,	,	PUNCT
fnp-3453	277	29	rhi	rhi	PROPN
fnp-3453	277	30	,	,	PUNCT
fnp-3453	277	31	and	and	CCONJ
fnp-3453	277	32	cte	cte	NOUN
fnp-3453	277	33	.	.	PUNCT
fnp-3453	278	1	these	these	DET
fnp-3453	278	2	results	result	NOUN
fnp-3453	278	3	provide	provide	VERB
fnp-3453	278	4	novel	novel	ADJ
fnp-3453	278	5	information	information	NOUN
fnp-3453	278	6	on	on	ADP
fnp-3453	278	7	basic	basic	ADJ
fnp-3453	278	8	neuroanatomy	neuroanatomy	NOUN
fnp-3453	278	9	of	of	ADP
fnp-3453	278	10	how	how	SCONJ
fnp-3453	278	11	closely	closely	ADV
fnp-3453	278	12	related	related	ADJ
fnp-3453	278	13	tissue	tissue	NOUN
fnp-3453	278	14	regions	region	NOUN
fnp-3453	278	15	might	might	AUX
fnp-3453	278	16	be	be	AUX
fnp-3453	278	17	significantly	significantly	ADV
fnp-3453	278	18	different	different	ADJ
fnp-3453	278	19	and	and	CCONJ
fnp-3453	278	20	result	result	VERB
fnp-3453	278	21	in	in	ADP
fnp-3453	278	22	unique	unique	ADJ
fnp-3453	278	23	neuropathologic	neuropathologic	ADJ
fnp-3453	278	24	features	feature	NOUN
fnp-3453	278	25	.	.	PUNCT
fnp-3453	279	1	to	to	ADP
fnp-3453	279	2	our	our	PRON
fnp-3453	279	3	knowledge	knowledge	NOUN
fnp-3453	279	4	,	,	PUNCT
fnp-3453	279	5	this	this	PRON
fnp-3453	279	6	is	be	AUX
fnp-3453	279	7	the	the	DET
fnp-3453	279	8	first	first	ADJ
fnp-3453	279	9	study	study	NOUN
fnp-3453	279	10	to	to	PART
fnp-3453	279	11	report	report	VERB
fnp-3453	279	12	such	such	ADJ
fnp-3453	279	13	findings	finding	NOUN
fnp-3453	279	14	.	.	PUNCT
fnp-3453	280	1	the	the	DET
fnp-3453	280	2	largest	large	ADJ
fnp-3453	280	3	category	category	NOUN
fnp-3453	280	4	of	of	ADP
fnp-3453	280	5	processes	process	NOUN
fnp-3453	280	6	was	be	AUX
fnp-3453	280	7	found	find	VERB
fnp-3453	280	8	to	to	PART
fnp-3453	280	9	be	be	AUX
fnp-3453	280	10	neuronal	neuronal	ADJ
fnp-3453	280	11	,	,	PUNCT
fnp-3453	280	12	and	and	CCONJ
fnp-3453	280	13	was	be	AUX
fnp-3453	280	14	downregulated	downregulate	VERB
fnp-3453	280	15	in	in	ADP
fnp-3453	280	16	the	the	DET
fnp-3453	280	17	sulcus	sulcus	NOUN
fnp-3453	280	18	compared	compare	VERB
fnp-3453	280	19	to	to	ADP
fnp-3453	280	20	the	the	DET
fnp-3453	280	21	crest	crest	NOUN
fnp-3453	280	22	.	.	PUNCT
fnp-3453	281	1	there	there	PRON
fnp-3453	281	2	are	be	VERB
fnp-3453	281	3	two	two	NUM
fnp-3453	281	4	possible	possible	ADJ
fnp-3453	281	5	explanations	explanation	NOUN
fnp-3453	281	6	for	for	ADP
fnp-3453	281	7	this	this	PRON
fnp-3453	281	8	,	,	PUNCT
fnp-3453	281	9	either	either	CCONJ
fnp-3453	281	10	the	the	DET
fnp-3453	281	11	sulcus	sulcus	NOUN
fnp-3453	281	12	has	have	VERB
fnp-3453	281	13	less	less	ADJ
fnp-3453	281	14	neurons	neuron	NOUN
fnp-3453	281	15	and	and	CCONJ
fnp-3453	281	16	supporting	support	VERB
fnp-3453	281	17	cells	cell	NOUN
fnp-3453	281	18	or	or	CCONJ
fnp-3453	281	19	there	there	PRON
fnp-3453	281	20	is	be	VERB
fnp-3453	281	21	a	a	DET
fnp-3453	281	22	persistent	persistent	ADJ
fnp-3453	281	23	neuronal	neuronal	ADJ
fnp-3453	281	24	impairment	impairment	NOUN
fnp-3453	281	25	found	find	VERB
fnp-3453	281	26	in	in	ADP
fnp-3453	281	27	the	the	DET
fnp-3453	281	28	sulcus	sulcus	NOUN
fnp-3453	281	29	across	across	ADP
fnp-3453	281	30	all	all	DET
fnp-3453	281	31	groups	group	NOUN
fnp-3453	281	32	.	.	PUNCT
fnp-3453	282	1	regardless	regardless	ADV
fnp-3453	282	2	which	which	PRON
fnp-3453	282	3	is	be	AUX
fnp-3453	282	4	correct	correct	ADJ
fnp-3453	282	5	,	,	PUNCT
fnp-3453	282	6	it	it	PRON
fnp-3453	282	7	is	be	AUX
fnp-3453	282	8	possible	possible	ADJ
fnp-3453	282	9	that	that	SCONJ
fnp-3453	282	10	an	an	DET
fnp-3453	282	11	impaired	impaired	ADJ
fnp-3453	282	12	or	or	CCONJ
fnp-3453	282	13	reduced	reduce	VERB
fnp-3453	282	14	neuronal	neuronal	ADJ
fnp-3453	282	15	response	response	NOUN
fnp-3453	282	16	might	might	AUX
fnp-3453	282	17	predispose	predispose	VERB
fnp-3453	282	18	the	the	DET
fnp-3453	282	19	sulcus	sulcus	NOUN
fnp-3453	282	20	to	to	ADP
fnp-3453	282	21	elevated	elevated	ADJ
fnp-3453	282	22	damage	damage	NOUN
fnp-3453	282	23	post	post	NOUN
fnp-3453	282	24	head	head	NOUN
fnp-3453	282	25	trauma	trauma	NOUN
fnp-3453	282	26	.	.	PUNCT
fnp-3453	283	1	the	the	DET
fnp-3453	283	2	next	next	ADV
fnp-3453	283	3	largest	large	ADJ
fnp-3453	283	4	category	category	NOUN
fnp-3453	283	5	of	of	ADP
fnp-3453	283	6	processes	process	NOUN
fnp-3453	283	7	were	be	AUX
fnp-3453	283	8	immune	immune	ADJ
fnp-3453	283	9	related	relate	VERB
fnp-3453	283	10	.	.	PUNCT
fnp-3453	284	1	interestingly	interestingly	ADV
fnp-3453	284	2	,	,	PUNCT
fnp-3453	284	3	the	the	DET
fnp-3453	284	4	majority	majority	NOUN
fnp-3453	284	5	of	of	ADP
fnp-3453	284	6	these	these	DET
fnp-3453	284	7	processes	process	NOUN
fnp-3453	284	8	were	be	AUX
fnp-3453	284	9	elevated	elevate	VERB
fnp-3453	284	10	compared	compare	VERB
fnp-3453	284	11	to	to	ADP
fnp-3453	284	12	the	the	DET
fnp-3453	284	13	crest	crest	NOUN
fnp-3453	284	14	.	.	PUNCT
fnp-3453	285	1	this	this	PRON
fnp-3453	285	2	suggests	suggest	VERB
fnp-3453	285	3	that	that	SCONJ
fnp-3453	285	4	the	the	DET
fnp-3453	285	5	sulcus	sulcus	NOUN
fnp-3453	285	6	might	might	AUX
fnp-3453	285	7	already	already	ADV
fnp-3453	285	8	be	be	AUX
fnp-3453	285	9	“	"	PUNCT
fnp-3453	285	10	primed	prime	VERB
fnp-3453	285	11	”	"	PUNCT
fnp-3453	285	12	to	to	PART
fnp-3453	285	13	have	have	VERB
fnp-3453	285	14	an	an	DET
fnp-3453	285	15	exaggerated	exaggerated	ADJ
fnp-3453	285	16	immune	immune	ADJ
fnp-3453	285	17	reaction	reaction	NOUN
fnp-3453	285	18	.	.	PUNCT
fnp-3453	286	1	the	the	DET
fnp-3453	286	2	primed	prime	VERB
fnp-3453	286	3	phenotype	phenotype	NOUN
fnp-3453	286	4	could	could	AUX
fnp-3453	286	5	be	be	AUX
fnp-3453	286	6	consistent	consistent	ADJ
fnp-3453	286	7	with	with	ADP
fnp-3453	286	8	having	have	VERB
fnp-3453	286	9	more	more	ADJ
fnp-3453	286	10	glial	glial	ADJ
fnp-3453	286	11	present	present	NOUN
fnp-3453	286	12	or	or	CCONJ
fnp-3453	286	13	the	the	DET
fnp-3453	286	14	current	current	ADJ
fnp-3453	286	15	glia	glia	NOUN
fnp-3453	286	16	might	might	AUX
fnp-3453	286	17	be	be	AUX
fnp-3453	286	18	predisposed	predispose	VERB
fnp-3453	286	19	to	to	PART
fnp-3453	286	20	have	have	VERB
fnp-3453	286	21	a	a	DET
fnp-3453	286	22	more	more	ADV
fnp-3453	286	23	severe	severe	ADJ
fnp-3453	286	24	immune	immune	ADJ
fnp-3453	286	25	reaction	reaction	NOUN
fnp-3453	286	26	.	.	PUNCT
fnp-3453	287	1	additionally	additionally	ADV
fnp-3453	287	2	,	,	PUNCT
fnp-3453	287	3	the	the	DET
fnp-3453	287	4	sulcus	sulcus	NOUN
fnp-3453	287	5	was	be	AUX
fnp-3453	287	6	observed	observe	VERB
fnp-3453	287	7	to	to	PART
fnp-3453	287	8	be	be	AUX
fnp-3453	287	9	positively	positively	ADV
fnp-3453	287	10	enriched	enrich	VERB
fnp-3453	287	11	in	in	ADP
fnp-3453	287	12	ecm	ecm	NOUN
fnp-3453	287	13	and	and	CCONJ
fnp-3453	287	14	vascular	vascular	ADJ
fnp-3453	287	15	processes	process	NOUN
fnp-3453	287	16	compared	compare	VERB
fnp-3453	287	17	to	to	ADP
fnp-3453	287	18	the	the	DET
fnp-3453	287	19	crest	crest	NOUN
fnp-3453	287	20	,	,	PUNCT
fnp-3453	287	21	further	far	ADV
fnp-3453	287	22	demonstrating	demonstrate	VERB
fnp-3453	287	23	the	the	DET
fnp-3453	287	24	sulcus	sulcus	NOUN
fnp-3453	287	25	is	be	AUX
fnp-3453	287	26	comprised	comprise	VERB
fnp-3453	287	27	of	of	ADP
fnp-3453	287	28	a	a	DET
fnp-3453	287	29	unique	unique	ADJ
fnp-3453	287	30	environment	environment	NOUN
fnp-3453	287	31	that	that	PRON
fnp-3453	287	32	responds	respond	VERB
fnp-3453	287	33	differently	differently	ADV
fnp-3453	287	34	during	during	ADP
fnp-3453	287	35	pathology	pathology	NOUN
fnp-3453	287	36	compared	compare	VERB
fnp-3453	287	37	to	to	ADP
fnp-3453	287	38	other	other	ADJ
fnp-3453	287	39	neighboring	neighboring	NOUN
fnp-3453	287	40	regions	region	NOUN
fnp-3453	287	41	.	.	PUNCT
fnp-3453	288	1	although	although	SCONJ
fnp-3453	288	2	it	it	PRON
fnp-3453	288	3	is	be	AUX
fnp-3453	288	4	likely	likely	ADJ
fnp-3453	288	5	the	the	DET
fnp-3453	288	6	physics	physics	NOUN
fnp-3453	288	7	of	of	ADP
fnp-3453	288	8	head	head	NOUN
fnp-3453	288	9	trauma	trauma	NOUN
fnp-3453	288	10	induced	induce	VERB
fnp-3453	288	11	damage	damage	NOUN
fnp-3453	288	12	and	and	CCONJ
fnp-3453	288	13	sulcal	sulcal	ADJ
fnp-3453	288	14	force	force	NOUN
fnp-3453	288	15	concentration	concentration	NOUN
fnp-3453	288	16	are	be	AUX
fnp-3453	288	17	the	the	DET
fnp-3453	288	18	main	main	ADJ
fnp-3453	288	19	driver	driver	NOUN
fnp-3453	288	20	of	of	ADP
fnp-3453	288	21	sulcal	sulcal	ADJ
fnp-3453	288	22	specific	specific	ADJ
fnp-3453	288	23	pathology	pathology	NOUN
fnp-3453	288	24	[	[	X
fnp-3453	288	25	11	11	NUM
fnp-3453	288	26	]	]	PUNCT
fnp-3453	288	27	,	,	PUNCT
fnp-3453	288	28	the	the	DET
fnp-3453	288	29	findings	finding	NOUN
fnp-3453	288	30	reported	report	VERB
fnp-3453	288	31	here	here	ADV
fnp-3453	288	32	could	could	AUX
fnp-3453	288	33	describe	describe	VERB
fnp-3453	288	34	additional	additional	ADJ
fnp-3453	288	35	mechanisms	mechanism	NOUN
fnp-3453	288	36	explaining	explain	VERB
fnp-3453	288	37	how	how	SCONJ
fnp-3453	288	38	the	the	DET
fnp-3453	288	39	sulcus	sulcus	NOUN
fnp-3453	288	40	is	be	AUX
fnp-3453	288	41	preferentially	preferentially	ADV
fnp-3453	288	42	affected	affect	VERB
fnp-3453	288	43	after	after	ADP
fnp-3453	288	44	repetitive	repetitive	ADJ
fnp-3453	288	45	head	head	NOUN
fnp-3453	288	46	trauma	trauma	NOUN
fnp-3453	288	47	[	[	X
fnp-3453	288	48	3	3	NUM
fnp-3453	288	49	]	]	PUNCT
fnp-3453	288	50	.	.	PUNCT
fnp-3453	289	1	consistent	consistent	ADJ
fnp-3453	289	2	with	with	ADP
fnp-3453	289	3	our	our	PRON
fnp-3453	289	4	hypothesis	hypothesis	NOUN
fnp-3453	289	5	and	and	CCONJ
fnp-3453	289	6	previous	previous	ADJ
fnp-3453	289	7	observations	observation	NOUN
fnp-3453	289	8	,	,	PUNCT
fnp-3453	289	9	repetitive	repetitive	ADJ
fnp-3453	289	10	head	head	NOUN
fnp-3453	289	11	trauma	trauma	NOUN
fnp-3453	289	12	was	be	AUX
fnp-3453	289	13	also	also	ADV
fnp-3453	289	14	a	a	DET
fnp-3453	289	15	significant	significant	ADJ
fnp-3453	289	16	mechanism	mechanism	NOUN
fnp-3453	289	17	driving	drive	VERB
fnp-3453	289	18	sulcal	sulcal	ADJ
fnp-3453	289	19	specific	specific	ADJ
fnp-3453	289	20	genetic	genetic	ADJ
fnp-3453	289	21	alterations	alteration	NOUN
fnp-3453	289	22	.	.	PUNCT
fnp-3453	290	1	the	the	DET
fnp-3453	290	2	cte	cte	PROPN
fnp-3453	290	3	and	and	CCONJ
fnp-3453	290	4	rhi	rhi	PROPN
fnp-3453	290	5	group	group	PROPN
fnp-3453	290	6	were	be	AUX
fnp-3453	290	7	observed	observe	VERB
fnp-3453	290	8	to	to	PART
fnp-3453	290	9	be	be	AUX
fnp-3453	290	10	very	very	ADV
fnp-3453	290	11	similar	similar	ADJ
fnp-3453	290	12	in	in	ADP
fnp-3453	290	13	many	many	ADJ
fnp-3453	290	14	genes	gene	NOUN
fnp-3453	290	15	and	and	CCONJ
fnp-3453	290	16	biological	biological	ADJ
fnp-3453	290	17	processes	process	NOUN
fnp-3453	290	18	that	that	PRON
fnp-3453	290	19	were	be	AUX
fnp-3453	290	20	altered	alter	VERB
fnp-3453	290	21	in	in	ADP
fnp-3453	290	22	the	the	DET
fnp-3453	290	23	sulcus	sulcus	NOUN
fnp-3453	290	24	compared	compare	VERB
fnp-3453	290	25	to	to	ADP
fnp-3453	290	26	controls	control	NOUN
fnp-3453	290	27	(	(	PUNCT
fnp-3453	290	28	figure	figure	NOUN
fnp-3453	290	29	5	5	NUM
fnp-3453	290	30	)	)	PUNCT
fnp-3453	290	31	.	.	PUNCT
fnp-3453	291	1	the	the	DET
fnp-3453	291	2	changes	change	NOUN
fnp-3453	291	3	that	that	PRON
fnp-3453	291	4	were	be	AUX
fnp-3453	291	5	observed	observe	VERB
fnp-3453	291	6	to	to	PART
fnp-3453	291	7	be	be	AUX
fnp-3453	291	8	consistent	consistent	ADJ
fnp-3453	291	9	between	between	ADP
fnp-3453	291	10	the	the	DET
fnp-3453	291	11	rhi	rhi	PROPN
fnp-3453	291	12	and	and	CCONJ
fnp-3453	291	13	cte	cte	PROPN
fnp-3453	291	14	group	group	NOUN
fnp-3453	291	15	could	could	AUX
fnp-3453	291	16	be	be	AUX
fnp-3453	291	17	interpreted	interpret	VERB
fnp-3453	291	18	as	as	ADP
fnp-3453	291	19	trauma	trauma	NOUN
fnp-3453	291	20	related	relate	VERB
fnp-3453	291	21	alterations	alteration	NOUN
fnp-3453	291	22	,	,	PUNCT
fnp-3453	291	23	as	as	ADP
fnp-3453	291	24	a	a	DET
fnp-3453	291	25	common	common	ADJ
fnp-3453	291	26	feature	feature	NOUN
fnp-3453	291	27	of	of	ADP
fnp-3453	291	28	both	both	DET
fnp-3453	291	29	groups	group	NOUN
fnp-3453	291	30	is	be	AUX
fnp-3453	291	31	they	they	PRON
fnp-3453	291	32	share	share	VERB
fnp-3453	291	33	a	a	DET
fnp-3453	291	34	history	history	NOUN
fnp-3453	291	35	of	of	ADP
fnp-3453	291	36	repetitive	repetitive	ADJ
fnp-3453	291	37	head	head	NOUN
fnp-3453	291	38	trauma	trauma	NOUN
fnp-3453	291	39	received	receive	VERB
fnp-3453	291	40	from	from	ADP
fnp-3453	291	41	playing	play	VERB
fnp-3453	291	42	american	american	ADJ
fnp-3453	291	43	football	football	NOUN
fnp-3453	291	44	.	.	PUNCT
fnp-3453	292	1	it	it	PRON
fnp-3453	292	2	was	be	AUX
fnp-3453	292	3	unexpected	unexpected	ADJ
fnp-3453	292	4	to	to	PART
fnp-3453	292	5	observe	observe	VERB
fnp-3453	292	6	more	more	ADJ
fnp-3453	292	7	than	than	ADP
fnp-3453	292	8	half	half	NOUN
fnp-3453	292	9	of	of	ADP
fnp-3453	292	10	the	the	PRON
fnp-3453	292	11	of	of	ADP
fnp-3453	292	12	immune	immune	ADJ
fnp-3453	292	13	biological	biological	ADJ
fnp-3453	292	14	responses	response	NOUN
fnp-3453	292	15	in	in	ADP
fnp-3453	292	16	rhi	rhi	PROPN
fnp-3453	292	17	and	and	CCONJ
fnp-3453	292	18	cte	cte	PROPN
fnp-3453	292	19	were	be	AUX
fnp-3453	292	20	decreased	decrease	VERB
fnp-3453	292	21	in	in	ADP
fnp-3453	292	22	the	the	DET
fnp-3453	292	23	sulcus	sulcus	NOUN
fnp-3453	292	24	compared	compare	VERB
fnp-3453	292	25	to	to	ADP
fnp-3453	292	26	control	control	NOUN
fnp-3453	292	27	.	.	PUNCT
fnp-3453	293	1	previous	previous	ADJ
fnp-3453	293	2	work	work	NOUN
fnp-3453	293	3	had	have	AUX
fnp-3453	293	4	suggested	suggest	VERB
fnp-3453	293	5	that	that	SCONJ
fnp-3453	293	6	neuroinflammation	neuroinflammation	NOUN
fnp-3453	293	7	was	be	AUX
fnp-3453	293	8	a	a	DET
fnp-3453	293	9	prominent	prominent	ADJ
fnp-3453	293	10	feature	feature	NOUN
fnp-3453	293	11	of	of	ADP
fnp-3453	293	12	head	head	NOUN
fnp-3453	293	13	trauma	trauma	NOUN
fnp-3453	293	14	and	and	CCONJ
fnp-3453	293	15	likely	likely	ADV
fnp-3453	293	16	related	relate	VERB
fnp-3453	293	17	to	to	ADP
fnp-3453	293	18	initial	initial	ADJ
fnp-3453	293	19	p	p	PROPN
fnp-3453	293	20	-	-	PUNCT
fnp-3453	293	21	tau	tau	NOUN
fnp-3453	293	22	deposition	deposition	NOUN
fnp-3453	294	1	[	[	X
fnp-3453	294	2	7	7	NUM
fnp-3453	294	3	]	]	PUNCT
fnp-3453	294	4	.	.	PUNCT
fnp-3453	295	1	when	when	SCONJ
fnp-3453	295	2	examining	examine	VERB
fnp-3453	295	3	which	which	PRON
fnp-3453	295	4	biological	biological	ADJ
fnp-3453	295	5	processes	process	NOUN
fnp-3453	295	6	were	be	AUX
fnp-3453	295	7	altered	alter	VERB
fnp-3453	295	8	in	in	ADP
fnp-3453	295	9	the	the	DET
fnp-3453	295	10	sulcus	sulcus	NOUN
fnp-3453	295	11	,	,	PUNCT
fnp-3453	295	12	it	it	PRON
fnp-3453	295	13	was	be	AUX
fnp-3453	295	14	observed	observe	VERB
fnp-3453	295	15	that	that	SCONJ
fnp-3453	295	16	the	the	DET
fnp-3453	295	17	upregulated	upregulated	ADJ
fnp-3453	295	18	processes	process	NOUN
fnp-3453	295	19	were	be	AUX
fnp-3453	295	20	more	more	ADV
fnp-3453	295	21	related	related	ADJ
fnp-3453	295	22	to	to	ADP
fnp-3453	295	23	foreign	foreign	ADJ
fnp-3453	295	24	object	object	NOUN
fnp-3453	295	25	recognition	recognition	NOUN
fnp-3453	295	26	,	,	PUNCT
fnp-3453	295	27	antigen	antigen	ADJ
fnp-3453	295	28	presentation	presentation	NOUN
fnp-3453	295	29	,	,	PUNCT
fnp-3453	295	30	and	and	CCONJ
fnp-3453	295	31	lysosomal	lysosomal	ADJ
fnp-3453	295	32	function	function	NOUN
fnp-3453	295	33	,	,	PUNCT
fnp-3453	295	34	while	while	SCONJ
fnp-3453	295	35	the	the	DET
fnp-3453	295	36	downregulated	downregulate	VERB
fnp-3453	295	37	processes	process	NOUN
fnp-3453	295	38	were	be	AUX
fnp-3453	295	39	related	relate	VERB
fnp-3453	295	40	to	to	ADP
fnp-3453	295	41	inflammatory	inflammatory	ADJ
fnp-3453	295	42	cytokine	cytokine	NOUN
fnp-3453	295	43	production	production	NOUN
fnp-3453	295	44	and	and	CCONJ
fnp-3453	295	45	other	other	ADJ
fnp-3453	295	46	elements	element	NOUN
fnp-3453	295	47	related	relate	VERB
fnp-3453	295	48	to	to	ADP
fnp-3453	295	49	neurodegeneration	neurodegeneration	NOUN
fnp-3453	295	50	.	.	PUNCT
fnp-3453	296	1	this	this	PRON
fnp-3453	296	2	is	be	AUX
fnp-3453	296	3	consistent	consistent	ADJ
fnp-3453	296	4	with	with	ADP
fnp-3453	296	5	our	our	PRON
fnp-3453	296	6	previous	previous	ADJ
fnp-3453	296	7	study	study	NOUN
fnp-3453	296	8	demonstrating	demonstrate	VERB
fnp-3453	296	9	that	that	SCONJ
fnp-3453	296	10	after	after	ADP
fnp-3453	296	11	repetitive	repetitive	ADJ
fnp-3453	296	12	head	head	NOUN
fnp-3453	296	13	trauma	trauma	NOUN
fnp-3453	296	14	there	there	PRON
fnp-3453	296	15	was	be	VERB
fnp-3453	296	16	relatively	relatively	ADV
fnp-3453	296	17	unchanged	unchanged	ADJ
fnp-3453	296	18	numbers	number	NOUN
fnp-3453	296	19	of	of	ADP
fnp-3453	296	20	total	total	ADJ
fnp-3453	296	21	microglia	microglia	NOUN
fnp-3453	296	22	,	,	PUNCT
fnp-3453	296	23	but	but	CCONJ
fnp-3453	296	24	increased	increased	ADJ
fnp-3453	296	25	levels	level	NOUN
fnp-3453	296	26	of	of	ADP
fnp-3453	296	27	cells	cell	NOUN
fnp-3453	296	28	positive	positive	ADJ
fnp-3453	296	29	for	for	ADP
fnp-3453	296	30	cd68	cd68	PROPN
fnp-3453	296	31	,	,	PUNCT
fnp-3453	296	32	a	a	DET
fnp-3453	296	33	lysosomal	lysosomal	ADJ
fnp-3453	296	34	marker	marker	NOUN
fnp-3453	296	35	that	that	PRON
fnp-3453	296	36	is	be	AUX
fnp-3453	296	37	elevated	elevate	VERB
fnp-3453	296	38	during	during	ADP
fnp-3453	296	39	increased	increase	VERB
fnp-3453	296	40	phagocytosis	phagocytosis	NOUN
fnp-3453	296	41	and	and	CCONJ
fnp-3453	296	42	innate	innate	ADJ
fnp-3453	296	43	immune	immune	ADJ
fnp-3453	296	44	activation	activation	NOUN
fnp-3453	296	45	[	[	X
fnp-3453	296	46	8	8	NUM
fnp-3453	296	47	]	]	X
fnp-3453	296	48	furthermore	furthermore	ADV
fnp-3453	296	49	,	,	PUNCT
fnp-3453	296	50	tmem106b	tmem106b	ADJ
fnp-3453	296	51	genotype	genotype	NOUN
fnp-3453	296	52	,	,	PUNCT
fnp-3453	296	53	which	which	PRON
fnp-3453	296	54	is	be	AUX
fnp-3453	296	55	related	relate	VERB
fnp-3453	296	56	to	to	ADP
fnp-3453	296	57	lysosomal	lysosomal	ADJ
fnp-3453	296	58	and	and	CCONJ
fnp-3453	296	59	phagocytic	phagocytic	ADJ
fnp-3453	296	60	alterations	alteration	NOUN
fnp-3453	296	61	,	,	PUNCT
fnp-3453	296	62	has	have	AUX
fnp-3453	296	63	been	be	AUX
fnp-3453	296	64	also	also	ADV
fnp-3453	296	65	found	find	VERB
fnp-3453	296	66	to	to	PART
fnp-3453	296	67	relate	relate	VERB
fnp-3453	296	68	to	to	AUX
fnp-3453	296	69	cte	cte	VERB
fnp-3453	296	70	severity	severity	NOUN
fnp-3453	296	71	[	[	X
fnp-3453	296	72	5	5	NUM
fnp-3453	296	73	]	]	PUNCT
fnp-3453	296	74	.	.	PUNCT
fnp-3453	297	1	overall	overall	ADV
fnp-3453	297	2	,	,	PUNCT
fnp-3453	297	3	the	the	DET
fnp-3453	297	4	surprising	surprising	ADJ
fnp-3453	297	5	downregulation	downregulation	NOUN
fnp-3453	297	6	of	of	ADP
fnp-3453	297	7	multiple	multiple	ADJ
fnp-3453	297	8	immune	immune	NOUN
fnp-3453	297	9	-	-	PUNCT
fnp-3453	297	10	related	relate	VERB
fnp-3453	297	11	processes	process	NOUN
fnp-3453	297	12	may	may	AUX
fnp-3453	297	13	suggest	suggest	VERB
fnp-3453	297	14	that	that	SCONJ
fnp-3453	297	15	an	an	DET
fnp-3453	297	16	impaired	impaired	ADJ
fnp-3453	297	17	immune	immune	ADJ
fnp-3453	297	18	response	response	NOUN
fnp-3453	297	19	following	follow	VERB
fnp-3453	297	20	rhi	rhi	PROPN
fnp-3453	297	21	predisposes	predispose	VERB
fnp-3453	297	22	individuals	individual	NOUN
fnp-3453	297	23	to	to	ADP
fnp-3453	297	24	developing	develop	VERB
fnp-3453	297	25	initial	initial	ADJ
fnp-3453	297	26	tau	tau	PROPN
fnp-3453	297	27	pathology	pathology	NOUN
fnp-3453	297	28	cte	cte	PROPN
fnp-3453	297	29	.	.	PUNCT
fnp-3453	298	1	future	future	ADJ
fnp-3453	298	2	studies	study	NOUN
fnp-3453	298	3	examining	examine	VERB
fnp-3453	298	4	cell	cell	NOUN
fnp-3453	298	5	type	type	NOUN
fnp-3453	298	6	specific	specific	ADJ
fnp-3453	298	7	alterations	alteration	NOUN
fnp-3453	298	8	and	and	CCONJ
fnp-3453	298	9	the	the	DET
fnp-3453	298	10	effects	effect	NOUN
fnp-3453	298	11	of	of	ADP
fnp-3453	298	12	immune	immune	NOUN
fnp-3453	298	13	-	-	PUNCT
fnp-3453	298	14	related	relate	VERB
fnp-3453	298	15	genetic	genetic	ADJ
fnp-3453	298	16	polymorphisms	polymorphism	NOUN
fnp-3453	298	17	will	will	AUX
fnp-3453	298	18	be	be	AUX
fnp-3453	298	19	necessary	necessary	ADJ
fnp-3453	298	20	to	to	PART
fnp-3453	298	21	test	test	VERB
fnp-3453	298	22	this	this	DET
fnp-3453	298	23	hypothesis	hypothesis	NOUN
fnp-3453	298	24	.	.	PUNCT
fnp-3453	299	1	although	although	SCONJ
fnp-3453	299	2	the	the	DET
fnp-3453	299	3	cte	cte	NOUN
fnp-3453	299	4	and	and	CCONJ
fnp-3453	299	5	rhi	rhi	PROPN
fnp-3453	299	6	group	group	PROPN
fnp-3453	299	7	did	do	AUX
fnp-3453	299	8	overlap	overlap	VERB
fnp-3453	299	9	for	for	ADP
fnp-3453	299	10	many	many	ADJ
fnp-3453	299	11	alterations	alteration	NOUN
fnp-3453	299	12	,	,	PUNCT
fnp-3453	299	13	we	we	PRON
fnp-3453	299	14	observed	observe	VERB
fnp-3453	299	15	that	that	SCONJ
fnp-3453	299	16	the	the	DET
fnp-3453	299	17	predominant	predominant	ADJ
fnp-3453	299	18	unique	unique	ADJ
fnp-3453	299	19	rhi	rhi	NOUN
fnp-3453	299	20	genes	gene	NOUN
fnp-3453	299	21	and	and	CCONJ
fnp-3453	299	22	go	go	VERB
fnp-3453	299	23	processes	process	NOUN
fnp-3453	299	24	were	be	AUX
fnp-3453	299	25	related	relate	VERB
fnp-3453	299	26	to	to	ADP
fnp-3453	299	27	mitochondrial	mitochondrial	ADJ
fnp-3453	299	28	and	and	CCONJ
fnp-3453	299	29	metabolic	metabolic	NOUN
fnp-3453	299	30	activity	activity	NOUN
fnp-3453	299	31	.	.	PUNCT
fnp-3453	300	1	rhi	rhi	PROPN
fnp-3453	300	2	is	be	AUX
fnp-3453	300	3	a	a	DET
fnp-3453	300	4	group	group	NOUN
fnp-3453	300	5	of	of	ADP
fnp-3453	300	6	cases	case	NOUN
fnp-3453	300	7	that	that	PRON
fnp-3453	300	8	is	be	AUX
fnp-3453	300	9	defined	define	VERB
fnp-3453	300	10	by	by	ADP
fnp-3453	300	11	having	have	VERB
fnp-3453	300	12	exposure	exposure	NOUN
fnp-3453	300	13	to	to	ADP
fnp-3453	300	14	repetitive	repetitive	ADJ
fnp-3453	300	15	head	head	NOUN
fnp-3453	300	16	trauma	trauma	NOUN
fnp-3453	300	17	,	,	PUNCT
fnp-3453	300	18	but	but	CCONJ
fnp-3453	300	19	no	no	DET
fnp-3453	300	20	neurodegenerative	neurodegenerative	ADJ
fnp-3453	300	21	pathology	pathology	NOUN
fnp-3453	300	22	.	.	PUNCT
fnp-3453	301	1	therefore	therefore	ADV
fnp-3453	301	2	,	,	PUNCT
fnp-3453	301	3	it	it	PRON
fnp-3453	301	4	is	be	AUX
fnp-3453	301	5	intriguing	intriguing	ADJ
fnp-3453	301	6	to	to	PART
fnp-3453	301	7	observe	observe	VERB
fnp-3453	301	8	that	that	SCONJ
fnp-3453	301	9	there	there	PRON
fnp-3453	301	10	was	be	VERB
fnp-3453	301	11	a	a	DET
fnp-3453	301	12	strong	strong	ADJ
fnp-3453	301	13	metabolic	metabolic	NOUN
fnp-3453	301	14	deficit	deficit	NOUN
fnp-3453	301	15	present	present	NOUN
fnp-3453	301	16	even	even	ADV
fnp-3453	301	17	before	before	SCONJ
fnp-3453	301	18	pathology	pathology	NOUN
fnp-3453	301	19	occurs	occur	VERB
fnp-3453	301	20	.	.	PUNCT
fnp-3453	302	1	mitochondrial	mitochondrial	ADJ
fnp-3453	302	2	activity	activity	NOUN
fnp-3453	302	3	is	be	AUX
fnp-3453	302	4	heavily	heavily	ADV
fnp-3453	302	5	tied	tie	VERB
fnp-3453	302	6	to	to	ADP
fnp-3453	302	7	the	the	DET
fnp-3453	302	8	health	health	NOUN
fnp-3453	302	9	of	of	ADP
fnp-3453	302	10	the	the	DET
fnp-3453	302	11	cell	cell	NOUN
fnp-3453	302	12	and	and	CCONJ
fnp-3453	302	13	any	any	DET
fnp-3453	302	14	impairments	impairment	NOUN
fnp-3453	302	15	could	could	AUX
fnp-3453	302	16	directly	directly	ADV
fnp-3453	302	17	impact	impact	VERB
fnp-3453	302	18	cell	cell	NOUN
fnp-3453	302	19	function	function	NOUN
fnp-3453	302	20	.	.	PUNCT
fnp-3453	303	1	these	these	DET
fnp-3453	303	2	results	result	NOUN
fnp-3453	303	3	suggest	suggest	VERB
fnp-3453	303	4	that	that	SCONJ
fnp-3453	303	5	after	after	ADP
fnp-3453	303	6	a	a	DET
fnp-3453	303	7	history	history	NOUN
fnp-3453	303	8	of	of	ADP
fnp-3453	303	9	repetitive	repetitive	ADJ
fnp-3453	303	10	head	head	NOUN
fnp-3453	303	11	trauma	trauma	NOUN
fnp-3453	303	12	,	,	PUNCT
fnp-3453	303	13	mitochondrial	mitochondrial	ADJ
fnp-3453	303	14	dysfunction	dysfunction	NOUN
fnp-3453	303	15	might	might	AUX
fnp-3453	303	16	be	be	AUX
fnp-3453	303	17	the	the	DET
fnp-3453	303	18	main	main	ADJ
fnp-3453	303	19	element	element	NOUN
fnp-3453	303	20	driving	drive	VERB
fnp-3453	303	21	early	early	ADJ
fnp-3453	303	22	symptoms	symptom	NOUN
fnp-3453	303	23	and	and	CCONJ
fnp-3453	303	24	pathology	pathology	NOUN
fnp-3453	303	25	.	.	PUNCT
fnp-3453	304	1	additionally	additionally	ADV
fnp-3453	304	2	,	,	PUNCT
fnp-3453	304	3	there	there	PRON
fnp-3453	304	4	have	have	AUX
fnp-3453	304	5	been	be	AUX
fnp-3453	304	6	several	several	ADJ
fnp-3453	304	7	reports	report	NOUN
fnp-3453	304	8	of	of	ADP
fnp-3453	304	9	mitochondria	mitochondria	NOUN
fnp-3453	304	10	related	relate	VERB
fnp-3453	304	11	dysfunction	dysfunction	NOUN
fnp-3453	304	12	occurring	occur	VERB
fnp-3453	304	13	as	as	ADP
fnp-3453	304	14	a	a	DET
fnp-3453	304	15	consequence	consequence	NOUN
fnp-3453	304	16	of	of	ADP
fnp-3453	304	17	head	head	NOUN
fnp-3453	304	18	trauma	trauma	NOUN
fnp-3453	304	19	[	[	X
fnp-3453	304	20	13	13	NUM
fnp-3453	304	21	]	]	PUNCT
fnp-3453	304	22	.	.	PUNCT
fnp-3453	305	1	it	it	PRON
fnp-3453	305	2	is	be	AUX
fnp-3453	305	3	unclear	unclear	ADJ
fnp-3453	305	4	if	if	SCONJ
fnp-3453	305	5	there	there	PRON
fnp-3453	305	6	are	be	VERB
fnp-3453	305	7	a	a	DET
fnp-3453	305	8	specific	specific	ADJ
fnp-3453	305	9	cell	cell	NOUN
fnp-3453	305	10	type	type	NOUN
fnp-3453	305	11	that	that	PRON
fnp-3453	305	12	is	be	AUX
fnp-3453	305	13	most	most	ADV
fnp-3453	305	14	affected	affected	ADJ
fnp-3453	305	15	or	or	CCONJ
fnp-3453	305	16	what	what	PRON
fnp-3453	305	17	might	might	AUX
fnp-3453	305	18	be	be	AUX
fnp-3453	305	19	upstream	upstream	ADJ
fnp-3453	305	20	of	of	ADP
fnp-3453	305	21	the	the	DET
fnp-3453	305	22	mitochondrial	mitochondrial	ADJ
fnp-3453	305	23	dysfunction	dysfunction	NOUN
fnp-3453	305	24	,	,	PUNCT
fnp-3453	305	25	but	but	CCONJ
fnp-3453	305	26	these	these	DET
fnp-3453	305	27	results	result	NOUN
fnp-3453	305	28	point	point	VERB
fnp-3453	305	29	towards	towards	ADP
fnp-3453	305	30	another	another	DET
fnp-3453	305	31	possible	possible	ADJ
fnp-3453	305	32	therapeutic	therapeutic	ADJ
fnp-3453	305	33	target	target	NOUN
fnp-3453	305	34	to	to	PART
fnp-3453	305	35	treat	treat	VERB
fnp-3453	305	36	disease	disease	NOUN
fnp-3453	305	37	before	before	SCONJ
fnp-3453	305	38	p	p	PROPN
fnp-3453	305	39	-	-	PUNCT
fnp-3453	305	40	tau	tau	PROPN
fnp-3453	305	41	deposition	deposition	NOUN
fnp-3453	305	42	even	even	ADV
fnp-3453	305	43	begins	begin	VERB
fnp-3453	305	44	.	.	PUNCT
fnp-3453	306	1	finally	finally	ADV
fnp-3453	306	2	,	,	PUNCT
fnp-3453	306	3	we	we	PRON
fnp-3453	306	4	investigated	investigate	VERB
fnp-3453	306	5	the	the	DET
fnp-3453	306	6	contribution	contribution	NOUN
fnp-3453	306	7	of	of	ADP
fnp-3453	306	8	p	p	PROPN
fnp-3453	306	9	-	-	PUNCT
fnp-3453	306	10	tau	tau	NOUN
fnp-3453	306	11	pathology	pathology	NOUN
fnp-3453	306	12	to	to	ADP
fnp-3453	306	13	the	the	DET
fnp-3453	306	14	sulcal	sulcal	ADJ
fnp-3453	306	15	specific	specific	ADJ
fnp-3453	306	16	genetic	genetic	ADJ
fnp-3453	306	17	alterations	alteration	NOUN
fnp-3453	306	18	.	.	PUNCT
fnp-3453	307	1	when	when	SCONJ
fnp-3453	307	2	directly	directly	ADV
fnp-3453	307	3	comparing	compare	VERB
fnp-3453	307	4	sulcal	sulcal	ADJ
fnp-3453	307	5	specific	specific	ADJ
fnp-3453	307	6	changes	change	NOUN
fnp-3453	307	7	found	find	VERB
fnp-3453	307	8	in	in	ADP
fnp-3453	307	9	rhi	rhi	PROPN
fnp-3453	307	10	and	and	CCONJ
fnp-3453	307	11	cte	cte	PROPN
fnp-3453	307	12	,	,	PUNCT
fnp-3453	307	13	very	very	ADV
fnp-3453	307	14	few	few	ADJ
fnp-3453	307	15	differences	difference	NOUN
fnp-3453	307	16	were	be	AUX
fnp-3453	307	17	observed	observe	VERB
fnp-3453	307	18	.	.	PUNCT
fnp-3453	308	1	this	this	PRON
fnp-3453	308	2	was	be	AUX
fnp-3453	308	3	unsurprising	unsurprising	ADJ
fnp-3453	308	4	as	as	SCONJ
fnp-3453	308	5	our	our	PRON
fnp-3453	308	6	cte	cte	NOUN
fnp-3453	308	7	group	group	NOUN
fnp-3453	308	8	was	be	AUX
fnp-3453	308	9	restricted	restrict	VERB
fnp-3453	308	10	to	to	ADP
fnp-3453	308	11	cases	case	NOUN
fnp-3453	308	12	with	with	ADP
fnp-3453	308	13	low	low	ADJ
fnp-3453	308	14	stage	stage	NOUN
fnp-3453	308	15	cte	cte	NOUN
fnp-3453	308	16	and	and	CCONJ
fnp-3453	308	17	had	have	VERB
fnp-3453	308	18	minimal	minimal	ADJ
fnp-3453	308	19	tau	tau	PROPN
fnp-3453	308	20	pathology	pathology	NOUN
fnp-3453	308	21	.	.	PUNCT
fnp-3453	309	1	therefore	therefore	ADV
fnp-3453	309	2	,	,	PUNCT
fnp-3453	309	3	it	it	PRON
fnp-3453	309	4	is	be	AUX
fnp-3453	309	5	likely	likely	ADJ
fnp-3453	309	6	that	that	DET
fnp-3453	309	7	exposure	exposure	NOUN
fnp-3453	309	8	to	to	ADP
fnp-3453	309	9	repetitive	repetitive	ADJ
fnp-3453	309	10	head	head	NOUN
fnp-3453	309	11	trauma	trauma	NOUN
fnp-3453	309	12	was	be	AUX
fnp-3453	309	13	a	a	DET
fnp-3453	309	14	stronger	strong	ADJ
fnp-3453	309	15	driving	driving	NOUN
fnp-3453	309	16	force	force	NOUN
fnp-3453	309	17	for	for	ADP
fnp-3453	309	18	sulcal	sulcal	ADJ
fnp-3453	309	19	specific	specific	ADJ
fnp-3453	309	20	changes	change	NOUN
fnp-3453	309	21	than	than	ADP
fnp-3453	309	22	p	p	NOUN
fnp-3453	309	23	-	-	PUNCT
fnp-3453	309	24	tau	tau	NOUN
fnp-3453	309	25	pathology	pathology	NOUN
fnp-3453	309	26	in	in	ADP
fnp-3453	309	27	these	these	DET
fnp-3453	309	28	individuals	individual	NOUN
fnp-3453	309	29	.	.	PUNCT
fnp-3453	310	1	it	it	PRON
fnp-3453	310	2	is	be	AUX
fnp-3453	310	3	also	also	ADV
fnp-3453	310	4	likely	likely	ADJ
fnp-3453	310	5	that	that	SCONJ
fnp-3453	310	6	many	many	ADJ
fnp-3453	310	7	genes	gene	NOUN
fnp-3453	310	8	related	relate	VERB
fnp-3453	310	9	to	to	ADP
fnp-3453	310	10	repetitive	repetitive	ADJ
fnp-3453	310	11	head	head	NOUN
fnp-3453	310	12	trauma	trauma	NOUN
fnp-3453	310	13	are	be	AUX
fnp-3453	310	14	part	part	NOUN
fnp-3453	310	15	of	of	ADP
fnp-3453	310	16	the	the	DET
fnp-3453	310	17	p	p	PROPN
fnp-3453	310	18	-	-	PUNCT
fnp-3453	310	19	tau	tau	PROPN
fnp-3453	310	20	deposition	deposition	NOUN
fnp-3453	310	21	mechanisms	mechanism	NOUN
fnp-3453	310	22	and	and	CCONJ
fnp-3453	310	23	are	be	AUX
fnp-3453	310	24	not	not	PART
fnp-3453	310	25	necessarily	necessarily	ADV
fnp-3453	310	26	unique	unique	ADJ
fnp-3453	310	27	to	to	ADP
fnp-3453	310	28	cte	cte	PROPN
fnp-3453	310	29	.	.	PUNCT
fnp-3453	311	1	rhi	rhi	PROPN
fnp-3453	311	2	and	and	CCONJ
fnp-3453	311	3	cte	cte	PROPN
fnp-3453	311	4	might	might	AUX
fnp-3453	311	5	not	not	PART
fnp-3453	311	6	be	be	AUX
fnp-3453	311	7	district	district	NOUN
fnp-3453	311	8	pathologic	pathologic	ADJ
fnp-3453	311	9	groups	group	NOUN
fnp-3453	311	10	,	,	PUNCT
fnp-3453	311	11	rather	rather	ADV
fnp-3453	311	12	they	they	PRON
fnp-3453	311	13	exist	exist	VERB
fnp-3453	311	14	in	in	ADP
fnp-3453	311	15	a	a	DET
fnp-3453	311	16	spectrum	spectrum	NOUN
fnp-3453	311	17	.	.	PUNCT
fnp-3453	312	1	however	however	ADV
fnp-3453	312	2	,	,	PUNCT
fnp-3453	312	3	we	we	PRON
fnp-3453	312	4	were	be	AUX
fnp-3453	312	5	still	still	ADV
fnp-3453	312	6	able	able	ADJ
fnp-3453	312	7	to	to	PART
fnp-3453	312	8	identify	identify	VERB
fnp-3453	312	9	unique	unique	ADJ
fnp-3453	312	10	genes	gene	NOUN
fnp-3453	312	11	found	find	VERB
fnp-3453	312	12	altered	alter	VERB
fnp-3453	312	13	only	only	ADV
fnp-3453	312	14	in	in	ADP
fnp-3453	312	15	the	the	DET
fnp-3453	312	16	cte	cte	NOUN
fnp-3453	312	17	sulcus	sulcus	NOUN
fnp-3453	312	18	and	and	CCONJ
fnp-3453	312	19	therefore	therefore	ADV
fnp-3453	312	20	,	,	PUNCT
fnp-3453	312	21	likely	likely	ADV
fnp-3453	312	22	related	relate	VERB
fnp-3453	312	23	to	to	ADP
fnp-3453	312	24	p	p	PROPN
fnp-3453	312	25	-	-	PUNCT
fnp-3453	312	26	tau	tau	NOUN
fnp-3453	312	27	deposition	deposition	NOUN
fnp-3453	312	28	.	.	PUNCT
fnp-3453	313	1	the	the	DET
fnp-3453	313	2	main	main	ADJ
fnp-3453	313	3	cte	cte	NOUN
fnp-3453	313	4	unique	unique	ADJ
fnp-3453	313	5	genes	gene	NOUN
fnp-3453	313	6	and	and	CCONJ
fnp-3453	313	7	go	go	VERB
fnp-3453	313	8	processes	process	NOUN
fnp-3453	313	9	were	be	AUX
fnp-3453	313	10	related	relate	VERB
fnp-3453	313	11	to	to	ADP
fnp-3453	313	12	immune	immune	ADJ
fnp-3453	313	13	and	and	CCONJ
fnp-3453	313	14	cell	cell	NOUN
fnp-3453	313	15	damage	damage	NOUN
fnp-3453	313	16	further	far	ADV
fnp-3453	313	17	highlighting	highlight	VERB
fnp-3453	313	18	the	the	DET
fnp-3453	313	19	possible	possible	ADJ
fnp-3453	313	20	connection	connection	NOUN
fnp-3453	313	21	between	between	ADP
fnp-3453	313	22	p	p	PROPN
fnp-3453	313	23	-	-	PUNCT
fnp-3453	313	24	tau	tau	PROPN
fnp-3453	313	25	deposition	deposition	NOUN
fnp-3453	313	26	and	and	CCONJ
fnp-3453	313	27	the	the	DET
fnp-3453	313	28	immune	immune	ADJ
fnp-3453	313	29	system	system	NOUN
fnp-3453	313	30	.	.	PUNCT
fnp-3453	314	1	it	it	PRON
fnp-3453	314	2	is	be	AUX
fnp-3453	314	3	unclear	unclear	ADJ
fnp-3453	314	4	if	if	SCONJ
fnp-3453	314	5	these	these	DET
fnp-3453	314	6	unique	unique	ADJ
fnp-3453	314	7	cte	cte	NOUN
fnp-3453	314	8	genes	gene	NOUN
fnp-3453	314	9	are	be	AUX
fnp-3453	314	10	a	a	DET
fnp-3453	314	11	consequence	consequence	NOUN
fnp-3453	314	12	of	of	ADP
fnp-3453	314	13	p	p	PROPN
fnp-3453	314	14	-	-	PUNCT
fnp-3453	314	15	tau	tau	PROPN
fnp-3453	314	16	deposition	deposition	NOUN
fnp-3453	314	17	or	or	CCONJ
fnp-3453	314	18	act	act	VERB
fnp-3453	314	19	as	as	ADP
fnp-3453	314	20	a	a	DET
fnp-3453	314	21	mechanism	mechanism	NOUN
fnp-3453	314	22	that	that	PRON
fnp-3453	314	23	,	,	PUNCT
fnp-3453	314	24	in	in	ADP
fnp-3453	314	25	addition	addition	NOUN
fnp-3453	314	26	to	to	ADP
fnp-3453	314	27	other	other	ADJ
fnp-3453	314	28	trauma	trauma	NOUN
fnp-3453	314	29	related	relate	VERB
fnp-3453	314	30	pathways	pathway	NOUN
fnp-3453	314	31	,	,	PUNCT
fnp-3453	314	32	could	could	AUX
fnp-3453	314	33	lead	lead	VERB
fnp-3453	314	34	to	to	ADP
fnp-3453	314	35	p	p	PROPN
fnp-3453	314	36	-	-	PUNCT
fnp-3453	314	37	tau	tau	NOUN
fnp-3453	314	38	deposition	deposition	NOUN
fnp-3453	314	39	.	.	PUNCT
fnp-3453	315	1	however	however	ADV
fnp-3453	315	2	,	,	PUNCT
fnp-3453	315	3	these	these	DET
fnp-3453	315	4	observed	observe	VERB
fnp-3453	315	5	unique	unique	ADJ
fnp-3453	315	6	cte	cte	NOUN
fnp-3453	315	7	biological	biological	ADJ
fnp-3453	315	8	processes	process	NOUN
fnp-3453	315	9	are	be	AUX
fnp-3453	315	10	novel	novel	ADJ
fnp-3453	315	11	targets	target	NOUN
fnp-3453	315	12	for	for	ADP
fnp-3453	315	13	future	future	ADJ
fnp-3453	315	14	biomarkers	biomarker	NOUN
fnp-3453	315	15	studies	study	NOUN
fnp-3453	315	16	to	to	PART
fnp-3453	315	17	help	help	AUX
fnp-3453	315	18	identify	identify	VERB
fnp-3453	315	19	early	early	ADJ
fnp-3453	315	20	stage	stage	NOUN
fnp-3453	315	21	disease	disease	NOUN
fnp-3453	315	22	.	.	PUNCT
fnp-3453	316	1	there	there	PRON
fnp-3453	316	2	are	be	VERB
fnp-3453	316	3	several	several	ADJ
fnp-3453	316	4	limitations	limitation	NOUN
fnp-3453	316	5	in	in	ADP
fnp-3453	316	6	this	this	DET
fnp-3453	316	7	study	study	NOUN
fnp-3453	316	8	.	.	PUNCT
fnp-3453	317	1	rna	rna	NOUN
fnp-3453	317	2	-	-	PUNCT
fnp-3453	317	3	sequencing	sequencing	NOUN
fnp-3453	317	4	was	be	AUX
fnp-3453	317	5	done	do	VERB
fnp-3453	317	6	on	on	ADP
fnp-3453	317	7	bulk	bulk	ADJ
fnp-3453	317	8	tissue	tissue	NOUN
fnp-3453	317	9	so	so	SCONJ
fnp-3453	317	10	no	no	DET
fnp-3453	317	11	comments	comment	NOUN
fnp-3453	317	12	on	on	ADP
fnp-3453	317	13	the	the	DET
fnp-3453	317	14	contribution	contribution	NOUN
fnp-3453	317	15	of	of	ADP
fnp-3453	317	16	individual	individual	ADJ
fnp-3453	317	17	cells	cell	NOUN
fnp-3453	317	18	can	can	AUX
fnp-3453	317	19	be	be	AUX
fnp-3453	317	20	made	make	VERB
fnp-3453	317	21	at	at	ADP
fnp-3453	317	22	this	this	DET
fnp-3453	317	23	time	time	NOUN
fnp-3453	317	24	.	.	PUNCT
fnp-3453	318	1	future	future	ADJ
fnp-3453	318	2	work	work	NOUN
fnp-3453	318	3	utilizing	utilize	VERB
fnp-3453	318	4	single	single	ADJ
fnp-3453	318	5	cell	cell	NOUN
fnp-3453	318	6	technologies	technology	NOUN
fnp-3453	318	7	will	will	AUX
fnp-3453	318	8	be	be	AUX
fnp-3453	318	9	needed	need	VERB
fnp-3453	318	10	to	to	PART
fnp-3453	318	11	determine	determine	VERB
fnp-3453	318	12	the	the	DET
fnp-3453	318	13	specific	specific	ADJ
fnp-3453	318	14	effects	effect	NOUN
fnp-3453	318	15	of	of	ADP
fnp-3453	318	16	each	each	DET
fnp-3453	318	17	cell	cell	NOUN
fnp-3453	318	18	on	on	ADP
fnp-3453	318	19	the	the	DET
fnp-3453	318	20	sulcal	sulcal	ADJ
fnp-3453	318	21	environment	environment	NOUN
fnp-3453	318	22	during	during	ADP
fnp-3453	318	23	cte	cte	PROPN
fnp-3453	318	24	.	.	PUNCT
fnp-3453	319	1	furthermore	furthermore	ADV
fnp-3453	319	2	,	,	PUNCT
fnp-3453	319	3	it	it	PRON
fnp-3453	319	4	is	be	AUX
fnp-3453	319	5	difficult	difficult	ADJ
fnp-3453	319	6	to	to	PART
fnp-3453	319	7	determine	determine	VERB
fnp-3453	319	8	the	the	DET
fnp-3453	319	9	full	full	ADJ
fnp-3453	319	10	mechanistic	mechanistic	ADJ
fnp-3453	319	11	effect	effect	NOUN
fnp-3453	319	12	in	in	ADP
fnp-3453	319	13	studies	study	NOUN
fnp-3453	319	14	using	use	VERB
fnp-3453	319	15	post	post	ADJ
fnp-3453	319	16	-	-	ADJ
fnp-3453	319	17	mortem	mortem	ADJ
fnp-3453	319	18	human	human	ADJ
fnp-3453	319	19	tissue	tissue	NOUN
fnp-3453	319	20	,	,	PUNCT
fnp-3453	319	21	as	as	SCONJ
fnp-3453	319	22	we	we	PRON
fnp-3453	319	23	can	can	AUX
fnp-3453	319	24	only	only	ADV
fnp-3453	319	25	look	look	VERB
fnp-3453	319	26	at	at	ADP
fnp-3453	319	27	a	a	DET
fnp-3453	319	28	single	single	ADJ
fnp-3453	319	29	point	point	NOUN
fnp-3453	319	30	in	in	ADP
fnp-3453	319	31	time	time	NOUN
fnp-3453	319	32	at	at	ADP
fnp-3453	319	33	the	the	DET
fnp-3453	319	34	end	end	NOUN
fnp-3453	319	35	of	of	ADP
fnp-3453	319	36	the	the	DET
fnp-3453	319	37	donor	donor	NOUN
fnp-3453	319	38	’s	’s	PART
fnp-3453	319	39	life	life	NOUN
fnp-3453	319	40	.	.	PUNCT
fnp-3453	320	1	mechanistic	mechanistic	ADJ
fnp-3453	320	2	studies	study	NOUN
fnp-3453	320	3	using	use	VERB
fnp-3453	320	4	mouse	mouse	NOUN
fnp-3453	320	5	models	model	NOUN
fnp-3453	320	6	or	or	CCONJ
fnp-3453	320	7	cell	cell	NOUN
fnp-3453	320	8	culture	culture	NOUN
fnp-3453	320	9	systems	system	NOUN
fnp-3453	320	10	will	will	AUX
fnp-3453	320	11	be	be	AUX
fnp-3453	320	12	needed	need	VERB
fnp-3453	320	13	to	to	PART
fnp-3453	320	14	determine	determine	VERB
fnp-3453	320	15	if	if	SCONJ
fnp-3453	320	16	the	the	DET
fnp-3453	320	17	observed	observed	ADJ
fnp-3453	320	18	genes	gene	NOUN
fnp-3453	320	19	are	be	AUX
fnp-3453	320	20	mechanistically	mechanistically	ADV
fnp-3453	320	21	related	relate	VERB
fnp-3453	320	22	to	to	ADP
fnp-3453	320	23	pathologic	pathologic	ADJ
fnp-3453	320	24	or	or	CCONJ
fnp-3453	320	25	healthy	healthy	ADJ
fnp-3453	320	26	physiologic	physiologic	ADJ
fnp-3453	320	27	responses	response	NOUN
fnp-3453	320	28	.	.	PUNCT
fnp-3453	321	1	additionally	additionally	ADV
fnp-3453	321	2	,	,	PUNCT
fnp-3453	321	3	due	due	ADP
fnp-3453	321	4	to	to	ADP
fnp-3453	321	5	the	the	DET
fnp-3453	321	6	inherent	inherent	ADJ
fnp-3453	321	7	variation	variation	NOUN
fnp-3453	321	8	that	that	PRON
fnp-3453	321	9	is	be	AUX
fnp-3453	321	10	present	present	ADJ
fnp-3453	321	11	in	in	ADP
fnp-3453	321	12	human	human	ADJ
fnp-3453	321	13	studies	study	NOUN
fnp-3453	321	14	,	,	PUNCT
fnp-3453	321	15	a	a	DET
fnp-3453	321	16	larger	large	ADJ
fnp-3453	321	17	sample	sample	NOUN
fnp-3453	321	18	size	size	NOUN
fnp-3453	321	19	is	be	AUX
fnp-3453	321	20	needed	need	VERB
fnp-3453	321	21	to	to	PART
fnp-3453	321	22	identify	identify	VERB
fnp-3453	321	23	more	more	ADV
fnp-3453	321	24	subtle	subtle	ADJ
fnp-3453	321	25	changes	change	NOUN
fnp-3453	321	26	.	.	PUNCT
fnp-3453	322	1	as	as	SCONJ
fnp-3453	322	2	the	the	DET
fnp-3453	322	3	present	present	ADJ
fnp-3453	322	4	study	study	NOUN
fnp-3453	322	5	only	only	ADV
fnp-3453	322	6	focused	focus	VERB
fnp-3453	322	7	on	on	ADP
fnp-3453	322	8	early	early	ADJ
fnp-3453	322	9	disease	disease	NOUN
fnp-3453	322	10	,	,	PUNCT
fnp-3453	322	11	future	future	ADJ
fnp-3453	322	12	work	work	NOUN
fnp-3453	322	13	is	be	AUX
fnp-3453	322	14	also	also	ADV
fnp-3453	322	15	needed	need	VERB
fnp-3453	322	16	to	to	PART
fnp-3453	322	17	compare	compare	VERB
fnp-3453	322	18	the	the	DET
fnp-3453	322	19	changes	change	NOUN
fnp-3453	322	20	found	find	VERB
fnp-3453	322	21	in	in	ADP
fnp-3453	322	22	low	low	ADJ
fnp-3453	322	23	stage	stage	NOUN
fnp-3453	322	24	disease	disease	NOUN
fnp-3453	322	25	to	to	ADP
fnp-3453	322	26	high	high	ADJ
fnp-3453	322	27	stage	stage	NOUN
fnp-3453	322	28	cte	cte	NOUN
fnp-3453	322	29	to	to	PART
fnp-3453	322	30	determine	determine	VERB
fnp-3453	322	31	if	if	SCONJ
fnp-3453	322	32	processes	process	NOUN
fnp-3453	322	33	are	be	AUX
fnp-3453	322	34	similar	similar	ADJ
fnp-3453	322	35	.	.	PUNCT
fnp-3453	323	1	finally	finally	ADV
fnp-3453	323	2	,	,	PUNCT
fnp-3453	323	3	as	as	SCONJ
fnp-3453	323	4	all	all	PRON
fnp-3453	323	5	of	of	ADP
fnp-3453	323	6	the	the	DET
fnp-3453	323	7	observed	observed	ADJ
fnp-3453	323	8	changes	change	NOUN
fnp-3453	323	9	were	be	AUX
fnp-3453	323	10	based	base	VERB
fnp-3453	323	11	on	on	ADP
fnp-3453	323	12	mrna	mrna	PROPN
fnp-3453	323	13	,	,	PUNCT
fnp-3453	323	14	proteomic	proteomic	ADJ
fnp-3453	323	15	and	and	CCONJ
fnp-3453	323	16	histologic	histologic	ADJ
fnp-3453	323	17	studies	study	NOUN
fnp-3453	323	18	will	will	AUX
fnp-3453	323	19	be	be	AUX
fnp-3453	323	20	needed	need	VERB
fnp-3453	323	21	to	to	PART
fnp-3453	323	22	verify	verify	VERB
fnp-3453	323	23	if	if	SCONJ
fnp-3453	323	24	the	the	DET
fnp-3453	323	25	results	result	NOUN
fnp-3453	323	26	are	be	AUX
fnp-3453	323	27	also	also	ADV
fnp-3453	323	28	found	find	VERB
fnp-3453	323	29	at	at	ADP
fnp-3453	323	30	the	the	DET
fnp-3453	323	31	protein	protein	NOUN
fnp-3453	323	32	level	level	NOUN
fnp-3453	323	33	.	.	PUNCT
fnp-3453	324	1	in	in	ADP
fnp-3453	324	2	conclusion	conclusion	NOUN
fnp-3453	324	3	,	,	PUNCT
fnp-3453	324	4	these	these	DET
fnp-3453	324	5	results	result	NOUN
fnp-3453	324	6	provide	provide	VERB
fnp-3453	324	7	clear	clear	ADJ
fnp-3453	324	8	evidence	evidence	NOUN
fnp-3453	324	9	that	that	SCONJ
fnp-3453	324	10	there	there	PRON
fnp-3453	324	11	is	be	VERB
fnp-3453	324	12	a	a	DET
fnp-3453	324	13	complex	complex	ADJ
fnp-3453	324	14	molecular	molecular	ADJ
fnp-3453	324	15	response	response	NOUN
fnp-3453	324	16	occurring	occur	VERB
fnp-3453	324	17	in	in	ADP
fnp-3453	324	18	the	the	DET
fnp-3453	324	19	sulcus	sulcus	NOUN
fnp-3453	324	20	compared	compare	VERB
fnp-3453	324	21	to	to	ADP
fnp-3453	324	22	the	the	DET
fnp-3453	324	23	gyral	gyral	ADJ
fnp-3453	324	24	crest	crest	NOUN
fnp-3453	324	25	.	.	PUNCT
fnp-3453	325	1	even	even	ADV
fnp-3453	325	2	without	without	ADP
fnp-3453	325	3	exposure	exposure	NOUN
fnp-3453	325	4	to	to	ADP
fnp-3453	325	5	repetitive	repetitive	ADJ
fnp-3453	325	6	head	head	NOUN
fnp-3453	325	7	trauma	trauma	NOUN
fnp-3453	325	8	,	,	PUNCT
fnp-3453	325	9	the	the	DET
fnp-3453	325	10	sulcus	sulcus	NOUN
fnp-3453	325	11	had	have	VERB
fnp-3453	325	12	a	a	DET
fnp-3453	325	13	persistent	persistent	ADJ
fnp-3453	325	14	immune	immune	ADJ
fnp-3453	325	15	response	response	NOUN
fnp-3453	325	16	.	.	PUNCT
fnp-3453	326	1	in	in	ADP
fnp-3453	326	2	response	response	NOUN
fnp-3453	326	3	to	to	ADP
fnp-3453	326	4	rhi	rhi	PROPN
fnp-3453	326	5	,	,	PUNCT
fnp-3453	326	6	there	there	PRON
fnp-3453	326	7	was	be	VERB
fnp-3453	326	8	immune	immune	ADJ
fnp-3453	326	9	alteration	alteration	NOUN
fnp-3453	326	10	,	,	PUNCT
fnp-3453	326	11	metabolic	metabolic	NOUN
fnp-3453	326	12	/	/	SYM
fnp-3453	326	13	mitochondria	mitochondria	NOUN
fnp-3453	326	14	dysfunction	dysfunction	NOUN
fnp-3453	326	15	,	,	PUNCT
fnp-3453	326	16	vascular	vascular	ADJ
fnp-3453	326	17	,	,	PUNCT
fnp-3453	326	18	and	and	CCONJ
fnp-3453	326	19	ecm	ecm	NOUN
fnp-3453	326	20	impairment	impairment	NOUN
fnp-3453	326	21	.	.	PUNCT
fnp-3453	327	1	during	during	ADP
fnp-3453	327	2	cte	cte	NOUN
fnp-3453	327	3	pathogenesis	pathogenesis	NOUN
fnp-3453	327	4	,	,	PUNCT
fnp-3453	327	5	the	the	DET
fnp-3453	327	6	immune	immune	ADJ
fnp-3453	327	7	response	response	NOUN
fnp-3453	327	8	found	find	VERB
fnp-3453	327	9	in	in	ADP
fnp-3453	327	10	low	low	ADJ
fnp-3453	327	11	stage	stage	NOUN
fnp-3453	327	12	cte	cte	NOUN
fnp-3453	327	13	was	be	AUX
fnp-3453	327	14	not	not	PART
fnp-3453	327	15	observed	observe	VERB
fnp-3453	327	16	to	to	PART
fnp-3453	327	17	be	be	AUX
fnp-3453	327	18	tissue	tissue	NOUN
fnp-3453	327	19	destruction	destruction	NOUN
fnp-3453	327	20	,	,	PUNCT
fnp-3453	327	21	cell	cell	NOUN
fnp-3453	327	22	loss	loss	NOUN
fnp-3453	327	23	,	,	PUNCT
fnp-3453	327	24	overt	overt	ADJ
fnp-3453	327	25	neuroinflammation	neuroinflammation	NOUN
fnp-3453	327	26	,	,	PUNCT
fnp-3453	327	27	or	or	CCONJ
fnp-3453	327	28	other	other	ADJ
fnp-3453	327	29	neurodegenerative	neurodegenerative	ADJ
fnp-3453	327	30	related	related	ADJ
fnp-3453	327	31	responses	response	NOUN
fnp-3453	327	32	,	,	PUNCT
fnp-3453	327	33	rather	rather	ADV
fnp-3453	327	34	,	,	PUNCT
fnp-3453	327	35	it	it	PRON
fnp-3453	327	36	was	be	AUX
fnp-3453	327	37	more	more	ADV
fnp-3453	327	38	focused	focused	ADJ
fnp-3453	327	39	on	on	ADP
fnp-3453	327	40	antigen	antigen	ADJ
fnp-3453	327	41	presentation	presentation	NOUN
fnp-3453	327	42	,	,	PUNCT
fnp-3453	327	43	phagocytosis	phagocytosis	NOUN
fnp-3453	327	44	,	,	PUNCT
fnp-3453	327	45	and	and	CCONJ
fnp-3453	327	46	wound	wound	NOUN
fnp-3453	327	47	repair	repair	NOUN
fnp-3453	327	48	responses	response	NOUN
fnp-3453	327	49	.	.	PUNCT
fnp-3453	328	1	in	in	ADP
fnp-3453	328	2	addition	addition	NOUN
fnp-3453	328	3	to	to	ADP
fnp-3453	328	4	complex	complex	ADJ
fnp-3453	328	5	immune	immune	ADJ
fnp-3453	328	6	changes	change	NOUN
fnp-3453	328	7	,	,	PUNCT
fnp-3453	328	8	early	early	ADV
fnp-3453	328	9	mitochondrial	mitochondrial	ADJ
fnp-3453	328	10	,	,	PUNCT
fnp-3453	328	11	vascular	vascular	ADJ
fnp-3453	328	12	,	,	PUNCT
fnp-3453	328	13	ecm	ecm	NOUN
fnp-3453	328	14	,	,	PUNCT
fnp-3453	328	15	and	and	CCONJ
fnp-3453	328	16	neuronal	neuronal	ADJ
fnp-3453	328	17	activity	activity	NOUN
fnp-3453	328	18	are	be	AUX
fnp-3453	328	19	all	all	PRON
fnp-3453	328	20	affected	affect	VERB
fnp-3453	328	21	during	during	ADP
fnp-3453	328	22	repetitive	repetitive	ADJ
fnp-3453	328	23	head	head	NOUN
fnp-3453	328	24	trauma	trauma	NOUN
fnp-3453	328	25	induced	induce	VERB
fnp-3453	328	26	damage	damage	NOUN
fnp-3453	328	27	and	and	CCONJ
fnp-3453	328	28	early	early	ADJ
fnp-3453	328	29	tau	tau	PROPN
fnp-3453	328	30	deposition	deposition	NOUN
fnp-3453	328	31	,	,	PUNCT
fnp-3453	328	32	and	and	CCONJ
fnp-3453	328	33	represent	represent	VERB
fnp-3453	328	34	possible	possible	ADJ
fnp-3453	328	35	avenues	avenue	NOUN
fnp-3453	328	36	to	to	PART
fnp-3453	328	37	halt	halt	VERB
fnp-3453	328	38	cte	cte	NOUN
fnp-3453	328	39	pathogenesis	pathogenesis	NOUN
fnp-3453	328	40	and	and	CCONJ
fnp-3453	328	41	prevent	prevent	NOUN
fnp-3453	328	42	disease	disease	NOUN
fnp-3453	328	43	.	.	PUNCT
fnp-3453	329	1	these	these	DET
fnp-3453	329	2	results	result	NOUN
fnp-3453	329	3	help	help	VERB
fnp-3453	329	4	refine	refine	VERB
fnp-3453	329	5	our	our	PRON
fnp-3453	329	6	understanding	understanding	NOUN
fnp-3453	329	7	of	of	ADP
fnp-3453	329	8	the	the	DET
fnp-3453	329	9	neuroinflammatory	neuroinflammatory	ADJ
fnp-3453	329	10	environment	environment	NOUN
fnp-3453	329	11	present	present	ADJ
fnp-3453	329	12	during	during	ADP
fnp-3453	329	13	disease	disease	NOUN
fnp-3453	329	14	and	and	CCONJ
fnp-3453	329	15	will	will	AUX
fnp-3453	329	16	help	help	VERB
fnp-3453	329	17	guide	guide	VERB
fnp-3453	329	18	the	the	DET
fnp-3453	329	19	discovery	discovery	NOUN
fnp-3453	329	20	of	of	ADP
fnp-3453	329	21	future	future	ADJ
fnp-3453	329	22	therapeutic	therapeutic	ADJ
fnp-3453	329	23	strategies	strategy	NOUN
fnp-3453	329	24	and	and	CCONJ
fnp-3453	329	25	novel	novel	ADJ
fnp-3453	329	26	biomarkers	biomarker	NOUN
fnp-3453	329	27	.	.	PUNCT
fnp-3453	330	1	future	future	ADJ
fnp-3453	330	2	studies	study	NOUN
fnp-3453	330	3	will	will	AUX
fnp-3453	330	4	be	be	AUX
fnp-3453	330	5	crucial	crucial	ADJ
fnp-3453	330	6	to	to	PART
fnp-3453	330	7	further	far	ADV
fnp-3453	330	8	dissect	dissect	VERB
fnp-3453	330	9	and	and	CCONJ
fnp-3453	330	10	study	study	VERB
fnp-3453	330	11	the	the	DET
fnp-3453	330	12	observed	observe	VERB
fnp-3453	330	13	biological	biological	ADJ
fnp-3453	330	14	processes	process	NOUN
fnp-3453	330	15	provided	provide	VERB
fnp-3453	330	16	here	here	ADV
fnp-3453	330	17	to	to	PART
fnp-3453	330	18	better	well	ADV
fnp-3453	330	19	understand	understand	VERB
fnp-3453	330	20	the	the	DET
fnp-3453	330	21	full	full	ADJ
fnp-3453	330	22	spectrum	spectrum	NOUN
fnp-3453	330	23	of	of	ADP
fnp-3453	330	24	early	early	ADJ
fnp-3453	330	25	disease	disease	NOUN
fnp-3453	330	26	.	.	PUNCT
fnp-3453	331	1	acknowledgements	acknowledgement	NOUN
fnp-3453	331	2	this	this	DET
fnp-3453	331	3	work	work	NOUN
fnp-3453	331	4	was	be	AUX
fnp-3453	331	5	supported	support	VERB
fnp-3453	331	6	by	by	ADP
fnp-3453	331	7	grant	grant	NOUN
fnp-3453	331	8	funding	funding	NOUN
fnp-3453	331	9	from	from	ADP
fnp-3453	331	10	:	:	PUNCT
fnp-3453	331	11	nih	nih	PROPN
fnp-3453	331	12	(	(	PUNCT
fnp-3453	331	13	u19	u19	PROPN
fnp-3453	331	14	-	-	PUNCT
fnp-3453	331	15	ag068753	ag068753	PROPN
fnp-3453	331	16	,	,	PUNCT
fnp-3453	331	17	ag08122	ag08122	PROPN
fnp-3453	331	18	,	,	PUNCT
fnp-3453	331	19	ag054076	ag054076	PROPN
fnp-3453	331	20	)	)	PUNCT
fnp-3453	331	21	,	,	PUNCT
fnp-3453	331	22	nia	nia	PROPN
fnp-3453	331	23	(	(	PUNCT
fnp-3453	331	24	ag057902	ag057902	PROPN
fnp-3453	331	25	,	,	PUNCT
fnp-3453	331	26	ag06234	ag06234	PROPN
fnp-3453	331	27	,	,	PUNCT
fnp-3453	331	28	rf1ag054156	rf1ag054156	NOUN
fnp-3453	331	29	,	,	PUNCT
fnp-3453	331	30	rf1ag057768	rf1ag057768	PROPN
fnp-3453	331	31	)	)	PUNCT
fnp-3453	331	32	,	,	PUNCT
fnp-3453	331	33	ninds	nind	NOUN
fnp-3453	331	34	(	(	PUNCT
fnp-3453	331	35	u54ns115266	u54ns115266	NOUN
fnp-3453	331	36	,	,	PUNCT
fnp-3453	331	37	u01ns086659	u01ns086659	NOUN
fnp-3453	331	38	,	,	PUNCT
fnp-3453	331	39	and	and	CCONJ
fnp-3453	331	40	k23ns102399	k23ns102399	PROPN
fnp-3453	331	41	)	)	PUNCT
fnp-3453	331	42	,	,	PUNCT
fnp-3453	331	43	national	national	PROPN
fnp-3453	331	44	institute	institute	PROPN
fnp-3453	331	45	of	of	ADP
fnp-3453	331	46	aging	age	VERB
fnp-3453	331	47	boston	boston	PROPN
fnp-3453	331	48	university	university	PROPN
fnp-3453	331	49	ad	ad	NOUN
fnp-3453	331	50	center	center	NOUN
fnp-3453	331	51	(	(	PUNCT
fnp-3453	331	52	p30ag013846	p30ag013846	NOUN
fnp-3453	331	53	;	;	PUNCT
fnp-3453	331	54	supplement	supplement	NOUN
fnp-3453	331	55	0572063345	0572063345	NUM
fnp-3453	331	56	-	-	SYM
fnp-3453	331	57	5	5	NUM
fnp-3453	331	58	)	)	PUNCT
fnp-3453	331	59	;	;	PUNCT
fnp-3453	331	60	department	department	NOUN
fnp-3453	331	61	of	of	ADP
fnp-3453	331	62	veterans	veterans	PROPN
fnp-3453	331	63	affairs	affair	NOUN
fnp-3453	331	64	biorepository	biorepository	NOUN
fnp-3453	331	65	(	(	PUNCT
fnp-3453	331	66	bx002466	bx002466	PROPN
fnp-3453	331	67	)	)	PUNCT
fnp-3453	331	68	department	department	NOUN
fnp-3453	331	69	of	of	ADP
fnp-3453	331	70	veterans	veterans	PROPN
fnp-3453	331	71	affairs	affairs	PROPN
fnp-3453	331	72	merit	merit	PROPN
fnp-3453	331	73	award	award	PROPN
fnp-3453	331	74	(	(	PUNCT
fnp-3453	331	75	i01	i01	NOUN
fnp-3453	331	76	-	-	PUNCT
fnp-3453	331	77	cx001038	cx001038	PROPN
fnp-3453	331	78	)	)	PUNCT
fnp-3453	331	79	,	,	PUNCT
fnp-3453	331	80	department	department	NOUN
fnp-3453	331	81	of	of	ADP
fnp-3453	331	82	veterans	veterans	PROPN
fnp-3453	331	83	affairs	affairs	PROPN
fnp-3453	331	84	career	career	NOUN
fnp-3453	331	85	development	development	PROPN
fnp-3453	331	86	award	award	PROPN
fnp-3453	331	87	(	(	PUNCT
fnp-3453	331	88	bx004349	bx004349	PROPN
fnp-3453	331	89	)	)	PUNCT
fnp-3453	331	90	,	,	PUNCT
fnp-3453	331	91	and	and	CCONJ
fnp-3453	331	92	the	the	DET
fnp-3453	331	93	nick	nick	PROPN
fnp-3453	331	94	and	and	CCONJ
fnp-3453	331	95	lynn	lynn	PROPN
fnp-3453	331	96	buoniconti	buoniconti	PROPN
fnp-3453	331	97	foundation	foundation	PROPN
fnp-3453	331	98	.	.	PUNCT
fnp-3453	332	1	the	the	DET
fnp-3453	332	2	views	view	NOUN
fnp-3453	332	3	,	,	PUNCT
fnp-3453	332	4	opinions	opinion	NOUN
fnp-3453	332	5	,	,	PUNCT
fnp-3453	332	6	and/or	and/or	CCONJ
fnp-3453	332	7	findings	finding	NOUN
fnp-3453	332	8	contained	contain	VERB
fnp-3453	332	9	in	in	ADP
fnp-3453	332	10	this	this	DET
fnp-3453	332	11	article	article	NOUN
fnp-3453	332	12	are	be	AUX
fnp-3453	332	13	those	those	PRON
fnp-3453	332	14	of	of	ADP
fnp-3453	332	15	the	the	DET
fnp-3453	332	16	authors	author	NOUN
fnp-3453	332	17	and	and	CCONJ
fnp-3453	332	18	should	should	AUX
fnp-3453	332	19	not	not	PART
fnp-3453	332	20	be	be	AUX
fnp-3453	332	21	construed	construe	VERB
fnp-3453	332	22	as	as	ADP
fnp-3453	332	23	an	an	DET
fnp-3453	332	24	official	official	ADJ
fnp-3453	332	25	veterans	veteran	NOUN
fnp-3453	332	26	affairs	affairs	PROPN
fnp-3453	332	27	or	or	CCONJ
fnp-3453	332	28	department	department	PROPN
fnp-3453	332	29	of	of	ADP
fnp-3453	332	30	defense	defense	NOUN
fnp-3453	332	31	position	position	NOUN
fnp-3453	332	32	,	,	PUNCT
fnp-3453	332	33	policy	policy	NOUN
fnp-3453	332	34	,	,	PUNCT
fnp-3453	332	35	or	or	CCONJ
fnp-3453	332	36	decision	decision	NOUN
fnp-3453	332	37	,	,	PUNCT
fnp-3453	332	38	unless	unless	SCONJ
fnp-3453	332	39	so	so	ADV
fnp-3453	332	40	designated	designate	VERB
fnp-3453	332	41	by	by	ADP
fnp-3453	332	42	other	other	ADJ
fnp-3453	332	43	official	official	ADJ
fnp-3453	332	44	documentation	documentation	NOUN
fnp-3453	332	45	.	.	PUNCT
fnp-3453	333	1	funders	funder	NOUN
fnp-3453	333	2	did	do	AUX
fnp-3453	333	3	not	not	PART
fnp-3453	333	4	have	have	VERB
fnp-3453	333	5	a	a	DET
fnp-3453	333	6	role	role	NOUN
fnp-3453	333	7	in	in	ADP
fnp-3453	333	8	the	the	DET
fnp-3453	333	9	design	design	NOUN
fnp-3453	333	10	and	and	CCONJ
fnp-3453	333	11	conduct	conduct	NOUN
fnp-3453	333	12	of	of	ADP
fnp-3453	333	13	the	the	DET
fnp-3453	333	14	study	study	NOUN
fnp-3453	333	15	;	;	PUNCT
fnp-3453	333	16	collection	collection	NOUN
fnp-3453	333	17	,	,	PUNCT
fnp-3453	333	18	management	management	NOUN
fnp-3453	333	19	,	,	PUNCT
fnp-3453	333	20	analysis	analysis	NOUN
fnp-3453	333	21	,	,	PUNCT
fnp-3453	333	22	and	and	CCONJ
fnp-3453	333	23	interpretation	interpretation	NOUN
fnp-3453	333	24	of	of	ADP
fnp-3453	333	25	the	the	DET
fnp-3453	333	26	data	datum	NOUN
fnp-3453	333	27	;	;	PUNCT
fnp-3453	333	28	preparation	preparation	NOUN
fnp-3453	333	29	,	,	PUNCT
fnp-3453	333	30	review	review	NOUN
fnp-3453	333	31	,	,	PUNCT
fnp-3453	333	32	or	or	CCONJ
fnp-3453	333	33	approval	approval	NOUN
fnp-3453	333	34	of	of	ADP
fnp-3453	333	35	the	the	DET
fnp-3453	333	36	manuscript	manuscript	NOUN
fnp-3453	333	37	;	;	PUNCT
fnp-3453	333	38	or	or	CCONJ
fnp-3453	333	39	decision	decision	NOUN
fnp-3453	333	40	to	to	PART
fnp-3453	333	41	submit	submit	VERB
fnp-3453	333	42	the	the	DET
fnp-3453	333	43	manuscript	manuscript	NOUN
fnp-3453	333	44	for	for	ADP
fnp-3453	333	45	publication	publication	NOUN
fnp-3453	333	46	.	.	PUNCT
fnp-3453	334	1	references	reference	NOUN
fnp-3453	334	2	1	1	NUM
fnp-3453	334	3	.	.	PUNCT
fnp-3453	335	1	agus	agus	PROPN
fnp-3453	335	2	f	f	PROPN
fnp-3453	335	3	,	,	PUNCT
fnp-3453	335	4	crespo	crespo	PROPN
fnp-3453	336	1	d	d	PROPN
fnp-3453	336	2	,	,	PUNCT
fnp-3453	336	3	myers	myers	PROPN
fnp-3453	336	4	rh	rh	PROPN
fnp-3453	336	5	,	,	PUNCT
fnp-3453	336	6	labadorf	labadorf	PROPN
fnp-3453	336	7	a	a	PRON
fnp-3453	336	8	(	(	PUNCT
fnp-3453	336	9	2019	2019	NUM
fnp-3453	336	10	)	)	PUNCT
fnp-3453	336	11	the	the	DET
fnp-3453	336	12	caudate	caudate	ADJ
fnp-3453	336	13	nucleus	nucleus	NOUN
fnp-3453	336	14	undergoes	undergo	VERB
fnp-3453	336	15	dramatic	dramatic	ADJ
fnp-3453	336	16	and	and	CCONJ
fnp-3453	336	17	unique	unique	ADJ
fnp-3453	336	18	transcriptional	transcriptional	ADJ
fnp-3453	336	19	changes	change	NOUN
fnp-3453	336	20	in	in	ADP
fnp-3453	336	21	human	human	ADJ
fnp-3453	336	22	prodromal	prodromal	ADJ
fnp-3453	336	23	huntington	huntington	PROPN
fnp-3453	336	24	's	's	PART
fnp-3453	336	25	disease	disease	NOUN
fnp-3453	336	26	brain	brain	NOUN
fnp-3453	336	27	.	.	PUNCT
fnp-3453	337	1	bmc	bmc	PROPN
fnp-3453	337	2	med	med	ADJ
fnp-3453	337	3	genomics	genomic	NOUN
fnp-3453	337	4	12	12	NUM
fnp-3453	337	5	:	:	SYM
fnp-3453	337	6	137	137	NUM
fnp-3453	337	7	https://doi.org/10.1186/s12920-019-0581-9	https://doi.org/10.1186/s12920-019-0581-9	NUM
fnp-3453	337	8	2	2	NUM
fnp-3453	337	9	.	.	X
fnp-3453	337	10	alosco	alosco	PROPN
fnp-3453	337	11	ml	ml	PROPN
fnp-3453	337	12	,	,	PUNCT
fnp-3453	337	13	cherry	cherry	PROPN
fnp-3453	337	14	jd	jd	PROPN
fnp-3453	337	15	,	,	PUNCT
fnp-3453	337	16	huber	huber	PROPN
fnp-3453	337	17	br	br	PROPN
fnp-3453	337	18	,	,	PUNCT
fnp-3453	337	19	tripodis	tripodis	PROPN
fnp-3453	337	20	y	y	PROPN
fnp-3453	337	21	,	,	PUNCT
fnp-3453	337	22	baucom	baucom	PROPN
fnp-3453	337	23	z	z	PROPN
fnp-3453	337	24	,	,	PUNCT
fnp-3453	337	25	kowall	kowall	VERB
fnp-3453	337	26	nw	nw	INTJ
fnp-3453	337	27	et	et	PROPN
fnp-3453	337	28	al	al	PROPN
fnp-3453	337	29	(	(	PUNCT
fnp-3453	337	30	2020	2020	NUM
fnp-3453	337	31	)	)	PUNCT
fnp-3453	337	32	characterizing	characterize	VERB
fnp-3453	337	33	tau	tau	PROPN
fnp-3453	337	34	deposition	deposition	NOUN
fnp-3453	337	35	in	in	ADP
fnp-3453	337	36	chronic	chronic	ADJ
fnp-3453	337	37	traumatic	traumatic	ADJ
fnp-3453	337	38	encephalopathy	encephalopathy	NOUN
fnp-3453	337	39	(	(	PUNCT
fnp-3453	337	40	cte	cte	NOUN
fnp-3453	337	41	):	):	PUNCT
fnp-3453	337	42	utility	utility	NOUN
fnp-3453	337	43	of	of	ADP
fnp-3453	337	44	the	the	DET
fnp-3453	337	45	mckee	mckee	PROPN
fnp-3453	337	46	cte	cte	PROPN
fnp-3453	337	47	staging	staging	NOUN
fnp-3453	337	48	scheme	scheme	NOUN
fnp-3453	337	49	.	.	PUNCT
fnp-3453	338	1	acta	acta	PROPN
fnp-3453	338	2	neuropathol	neuropathol	PROPN
fnp-3453	338	3	140	140	NUM
fnp-3453	338	4	:	:	PUNCT
fnp-3453	338	5	495	495	NUM
fnp-3453	338	6	-	-	SYM
fnp-3453	338	7	512	512	NUM
fnp-3453	338	8	https://doi.org/10.1007/s00401-020-02197-9	https://doi.org/10.1007/s00401-020-02197-9	NOUN
fnp-3453	338	9	3	3	NUM
fnp-3453	338	10	.	.	PUNCT
fnp-3453	338	11	bieniek	bieniek	PROPN
fnp-3453	338	12	kf	kf	PROPN
fnp-3453	338	13	,	,	PUNCT
fnp-3453	338	14	cairns	cairns	PROPN
fnp-3453	338	15	nj	nj	PROPN
fnp-3453	338	16	,	,	PUNCT
fnp-3453	338	17	crary	crary	PROPN
fnp-3453	338	18	jf	jf	PROPN
fnp-3453	338	19	,	,	PUNCT
fnp-3453	338	20	dickson	dickson	PROPN
fnp-3453	338	21	dw	dw	PROPN
fnp-3453	338	22	,	,	PUNCT
fnp-3453	338	23	folkerth	folkerth	PROPN
fnp-3453	338	24	rd	rd	PROPN
fnp-3453	338	25	,	,	PUNCT
fnp-3453	338	26	keene	keene	PROPN
fnp-3453	338	27	cd	cd	PROPN
fnp-3453	338	28	et	et	PROPN
fnp-3453	338	29	al	al	PROPN
fnp-3453	338	30	(	(	PUNCT
fnp-3453	338	31	2021	2021	NUM
fnp-3453	338	32	)	)	PUNCT
fnp-3453	338	33	the	the	DET
fnp-3453	338	34	second	second	ADJ
fnp-3453	338	35	ninds	nind	NOUN
fnp-3453	338	36	/	/	SYM
fnp-3453	338	37	nibib	nibib	NOUN
fnp-3453	338	38	consensus	consensus	NOUN
fnp-3453	338	39	meeting	meeting	NOUN
fnp-3453	338	40	to	to	PART
fnp-3453	338	41	define	define	VERB
fnp-3453	338	42	neuropathological	neuropathological	ADJ
fnp-3453	338	43	criteria	criterion	NOUN
fnp-3453	338	44	for	for	ADP
fnp-3453	338	45	the	the	DET
fnp-3453	338	46	diagnosis	diagnosis	NOUN
fnp-3453	338	47	of	of	ADP
fnp-3453	338	48	chronic	chronic	ADJ
fnp-3453	338	49	traumatic	traumatic	ADJ
fnp-3453	338	50	encephalopathy	encephalopathy	NOUN
fnp-3453	338	51	.	.	PUNCT
fnp-3453	339	1	j	j	PROPN
fnp-3453	339	2	neuropathol	neuropathol	PROPN
fnp-3453	339	3	exp	exp	PROPN
fnp-3453	339	4	neurol	neurol	PROPN
fnp-3453	339	5	80	80	NUM
fnp-3453	339	6	:	:	SYM
fnp-3453	339	7	210	210	NUM
fnp-3453	339	8	-	-	SYM
fnp-3453	339	9	219	219	NUM
fnp-3453	339	10	https://doi.org/10.1093/jnen/nlab001	https://doi.org/10.1093/jnen/nlab001	DET
fnp-3453	339	11	4	4	NUM
fnp-3453	339	12	.	.	PUNCT
fnp-3453	340	1	cherry	cherry	PROPN
fnp-3453	340	2	jd	jd	PROPN
fnp-3453	340	3	,	,	PUNCT
fnp-3453	340	4	meng	meng	PROPN
fnp-3453	340	5	g	g	PROPN
fnp-3453	340	6	,	,	PUNCT
fnp-3453	340	7	daley	daley	PROPN
fnp-3453	340	8	s	s	PROPN
fnp-3453	340	9	,	,	PUNCT
fnp-3453	340	10	xia	xia	PROPN
fnp-3453	340	11	w	w	PROPN
fnp-3453	340	12	,	,	PUNCT
fnp-3453	340	13	svirsky	svirsky	PROPN
fnp-3453	340	14	s	s	NOUN
fnp-3453	340	15	,	,	PUNCT
fnp-3453	340	16	alvarez	alvarez	PROPN
fnp-3453	340	17	ve	ve	PROPN
fnp-3453	340	18	et	et	PROPN
fnp-3453	340	19	al	al	PROPN
fnp-3453	340	20	(	(	PUNCT
fnp-3453	340	21	2020	2020	NUM
fnp-3453	340	22	)	)	PUNCT
fnp-3453	340	23	ccl2	ccl2	NOUN
fnp-3453	340	24	is	be	AUX
fnp-3453	340	25	associated	associate	VERB
fnp-3453	340	26	with	with	ADP
fnp-3453	340	27	microglia	microglia	ADJ
fnp-3453	340	28	and	and	CCONJ
fnp-3453	340	29	macrophage	macrophage	ADJ
fnp-3453	340	30	recruitment	recruitment	NOUN
fnp-3453	340	31	in	in	ADP
fnp-3453	340	32	chronic	chronic	ADJ
fnp-3453	340	33	traumatic	traumatic	ADJ
fnp-3453	340	34	encephalopathy	encephalopathy	NOUN
fnp-3453	340	35	.	.	PUNCT
fnp-3453	341	1	j	j	PROPN
fnp-3453	341	2	neuroinflammation	neuroinflammation	NOUN
fnp-3453	341	3	17	17	NUM
fnp-3453	341	4	:	:	SYM
fnp-3453	341	5	370	370	NUM
fnp-3453	341	6	https://doi.org/10.1186/s12974-020-02036-4	https://doi.org/10.1186/s12974-020-02036-4	NUM
fnp-3453	341	7	5	5	NUM
fnp-3453	341	8	.	.	PUNCT
fnp-3453	342	1	cherry	cherry	PROPN
fnp-3453	342	2	jd	jd	PROPN
fnp-3453	342	3	,	,	PUNCT
fnp-3453	342	4	mez	mez	PROPN
fnp-3453	342	5	j	j	PROPN
fnp-3453	342	6	,	,	PUNCT
fnp-3453	342	7	crary	crary	PROPN
fnp-3453	342	8	jf	jf	PROPN
fnp-3453	342	9	,	,	PUNCT
fnp-3453	342	10	tripodis	tripodis	VERB
fnp-3453	342	11	y	y	PROPN
fnp-3453	342	12	,	,	PUNCT
fnp-3453	342	13	alvarez	alvarez	PROPN
fnp-3453	342	14	ve	ve	PROPN
fnp-3453	342	15	,	,	PUNCT
fnp-3453	342	16	mahar	mahar	PROPN
fnp-3453	343	1	i	i	INTJ
fnp-3453	343	2	et	et	PROPN
fnp-3453	343	3	al	al	PROPN
fnp-3453	343	4	(	(	PUNCT
fnp-3453	343	5	2018	2018	NUM
fnp-3453	343	6	)	)	PUNCT
fnp-3453	343	7	variation	variation	NOUN
fnp-3453	343	8	in	in	ADP
fnp-3453	343	9	tmem106b	tmem106b	PROPN
fnp-3453	343	10	in	in	ADP
fnp-3453	343	11	chronic	chronic	ADJ
fnp-3453	343	12	traumatic	traumatic	ADJ
fnp-3453	343	13	encephalopathy	encephalopathy	NOUN
fnp-3453	343	14	.	.	PUNCT
fnp-3453	344	1	acta	acta	PROPN
fnp-3453	344	2	neuropathologica	neuropathologica	PROPN
fnp-3453	344	3	communications	communication	NOUN
fnp-3453	344	4	6	6	NUM
fnp-3453	344	5	:	:	SYM
fnp-3453	344	6	115	115	NUM
fnp-3453	344	7	https://doi.org/10.1186/s40478-018-0619-9	https://doi.org/10.1186/s40478-018-0619-9	NUM
fnp-3453	344	8	6	6	NUM
fnp-3453	344	9	.	.	PUNCT
fnp-3453	345	1	cherry	cherry	PROPN
fnp-3453	345	2	jd	jd	PROPN
fnp-3453	345	3	,	,	PUNCT
fnp-3453	345	4	olschowka	olschowka	PROPN
fnp-3453	345	5	ja	ja	PROPN
fnp-3453	345	6	,	,	PUNCT
fnp-3453	345	7	o'banion	o'banion	PROPN
fnp-3453	345	8	mk	mk	PROPN
fnp-3453	345	9	(	(	PUNCT
fnp-3453	345	10	2014	2014	NUM
fnp-3453	345	11	)	)	PUNCT
fnp-3453	345	12	neuroinflammation	neuroinflammation	NOUN
fnp-3453	345	13	and	and	CCONJ
fnp-3453	345	14	m2	m2	PROPN
fnp-3453	345	15	microglia	microglia	PROPN
fnp-3453	345	16	:	:	PUNCT
fnp-3453	345	17	the	the	DET
fnp-3453	345	18	good	good	NOUN
fnp-3453	345	19	,	,	PUNCT
fnp-3453	345	20	the	the	DET
fnp-3453	345	21	bad	bad	ADJ
fnp-3453	345	22	,	,	PUNCT
fnp-3453	345	23	and	and	CCONJ
fnp-3453	345	24	the	the	DET
fnp-3453	345	25	inflamed	inflame	VERB
fnp-3453	345	26	.	.	PUNCT
fnp-3453	346	1	j	j	PROPN
fnp-3453	346	2	neuroinflammation	neuroinflammation	NOUN
fnp-3453	346	3	11	11	NUM
fnp-3453	346	4	:	:	SYM
fnp-3453	346	5	98	98	NUM
fnp-3453	346	6	https://doi.org/10.1186/1742-2094-11-98	https://doi.org/10.1186/1742-2094-11-98	ADJ
fnp-3453	346	7	7	7	NUM
fnp-3453	346	8	.	.	PUNCT
fnp-3453	347	1	cherry	cherry	PROPN
fnp-3453	347	2	jd	jd	PROPN
fnp-3453	347	3	,	,	PUNCT
fnp-3453	347	4	tripodis	tripodis	PROPN
fnp-3453	347	5	y	y	PROPN
fnp-3453	347	6	,	,	PUNCT
fnp-3453	347	7	alvarez	alvarez	PROPN
fnp-3453	347	8	ve	ve	PROPN
fnp-3453	347	9	,	,	PUNCT
fnp-3453	347	10	huber	huber	PROPN
fnp-3453	347	11	b	b	PROPN
fnp-3453	347	12	,	,	PUNCT
fnp-3453	347	13	kiernan	kiernan	PROPN
fnp-3453	347	14	pt	pt	PROPN
fnp-3453	347	15	,	,	PUNCT
fnp-3453	347	16	daneshvar	daneshvar	NOUN
fnp-3453	347	17	dh	dh	NOUN
fnp-3453	347	18	et	et	PROPN
fnp-3453	347	19	al	al	PROPN
fnp-3453	347	20	(	(	PUNCT
fnp-3453	347	21	2016	2016	NUM
fnp-3453	347	22	)	)	PUNCT
fnp-3453	347	23	microglial	microglial	ADJ
fnp-3453	347	24	neuroinflammation	neuroinflammation	NOUN
fnp-3453	347	25	contributes	contribute	VERB
fnp-3453	347	26	to	to	ADP
fnp-3453	347	27	tau	tau	PROPN
fnp-3453	347	28	accumulation	accumulation	NOUN
fnp-3453	347	29	in	in	ADP
fnp-3453	347	30	chronic	chronic	ADJ
fnp-3453	347	31	traumatic	traumatic	ADJ
fnp-3453	347	32	encephalopathy	encephalopathy	NOUN
fnp-3453	347	33	.	.	PUNCT
fnp-3453	348	1	acta	acta	PROPN
fnp-3453	348	2	neuropathol	neuropathol	PROPN
fnp-3453	348	3	commun	commun	PROPN
fnp-3453	348	4	4	4	NUM
fnp-3453	348	5	:	:	SYM
fnp-3453	348	6	112	112	NUM
fnp-3453	348	7	https://doi.org/10.1186/s40478-016-0382-8	https://doi.org/10.1186/s40478-016-0382-8	NUM
fnp-3453	348	8	8	8	NUM
fnp-3453	348	9	.	.	PUNCT
fnp-3453	349	1	chistiakov	chistiakov	PROPN
fnp-3453	349	2	da	da	PROPN
fnp-3453	349	3	,	,	PUNCT
fnp-3453	349	4	killingsworth	killingsworth	PROPN
fnp-3453	349	5	mc	mc	PROPN
fnp-3453	349	6	,	,	PUNCT
fnp-3453	349	7	myasoedova	myasoedova	PROPN
fnp-3453	349	8	va	va	PROPN
fnp-3453	349	9	,	,	PUNCT
fnp-3453	349	10	orekhov	orekhov	ADJ
fnp-3453	349	11	an	an	DET
fnp-3453	349	12	,	,	PUNCT
fnp-3453	349	13	bobryshev	bobryshev	PROPN
fnp-3453	349	14	yv	yv	PROPN
fnp-3453	349	15	(	(	PUNCT
fnp-3453	349	16	2017	2017	NUM
fnp-3453	349	17	)	)	PUNCT
fnp-3453	350	1	cd68	cd68	PROPN
fnp-3453	350	2	/	/	SYM
fnp-3453	350	3	macrosialin	macrosialin	NOUN
fnp-3453	350	4	:	:	PUNCT
fnp-3453	350	5	not	not	PART
fnp-3453	350	6	just	just	ADV
fnp-3453	350	7	a	a	DET
fnp-3453	350	8	histochemical	histochemical	ADJ
fnp-3453	350	9	marker	marker	NOUN
fnp-3453	350	10	.	.	PUNCT
fnp-3453	351	1	lab	lab	PROPN
fnp-3453	351	2	invest	invest	VERB
fnp-3453	351	3	97	97	NUM
fnp-3453	351	4	:	:	SYM
fnp-3453	351	5	4	4	NUM
fnp-3453	351	6	-	-	SYM
fnp-3453	351	7	13	13	NUM
fnp-3453	351	8	https://doi.org/10.1038/labinvest.2016.116	https://doi.org/10.1038/labinvest.2016.116	PROPN
fnp-3453	351	9	9	9	NUM
fnp-3453	351	10	.	.	PUNCT
fnp-3453	352	1	coughlin	coughlin	PROPN
fnp-3453	352	2	jm	jm	PROPN
fnp-3453	352	3	,	,	PUNCT
fnp-3453	352	4	wang	wang	PROPN
fnp-3453	352	5	y	y	PROPN
fnp-3453	352	6	,	,	PUNCT
fnp-3453	352	7	minn	minn	PROPN
fnp-3453	352	8	i	i	PROPN
fnp-3453	352	9	,	,	PUNCT
fnp-3453	352	10	bienko	bienko	ADJ
fnp-3453	352	11	n	n	CCONJ
fnp-3453	352	12	,	,	PUNCT
fnp-3453	352	13	ambinder	ambinder	PROPN
fnp-3453	352	14	eb	eb	PROPN
fnp-3453	352	15	,	,	PUNCT
fnp-3453	352	16	xu	xu	PROPN
fnp-3453	352	17	x	x	PUNCT
fnp-3453	352	18	et	et	PROPN
fnp-3453	352	19	al	al	PROPN
fnp-3453	352	20	(	(	PUNCT
fnp-3453	352	21	2017	2017	NUM
fnp-3453	352	22	)	)	PUNCT
fnp-3453	352	23	imaging	imaging	NOUN
fnp-3453	352	24	of	of	ADP
fnp-3453	352	25	glial	glial	ADJ
fnp-3453	352	26	cell	cell	NOUN
fnp-3453	352	27	activation	activation	NOUN
fnp-3453	352	28	and	and	CCONJ
fnp-3453	352	29	white	white	ADJ
fnp-3453	352	30	matter	matter	NOUN
fnp-3453	352	31	integrity	integrity	NOUN
fnp-3453	352	32	in	in	ADP
fnp-3453	352	33	brains	brain	NOUN
fnp-3453	352	34	of	of	ADP
fnp-3453	352	35	active	active	ADJ
fnp-3453	352	36	and	and	CCONJ
fnp-3453	352	37	recently	recently	ADV
fnp-3453	352	38	retired	retire	VERB
fnp-3453	352	39	national	national	PROPN
fnp-3453	352	40	football	football	PROPN
fnp-3453	352	41	league	league	PROPN
fnp-3453	352	42	players	player	NOUN
fnp-3453	352	43	.	.	PUNCT
fnp-3453	353	1	jama	jama	PROPN
fnp-3453	353	2	neurol	neurol	PROPN
fnp-3453	353	3	74	74	NUM
fnp-3453	353	4	:	:	SYM
fnp-3453	353	5	67	67	NUM
fnp-3453	353	6	-	-	SYM
fnp-3453	353	7	74	74	NUM
fnp-3453	353	8	https://doi.org/10.1001/jamaneurol.2016.3764	https://doi.org/10.1001/jamaneurol.2016.3764	PROPN
fnp-3453	353	9	10	10	NUM
fnp-3453	353	10	.	.	PUNCT
fnp-3453	354	1	coughlin	coughlin	PROPN
fnp-3453	354	2	jm	jm	PROPN
fnp-3453	354	3	,	,	PUNCT
fnp-3453	354	4	wang	wang	PROPN
fnp-3453	354	5	y	y	PROPN
fnp-3453	354	6	,	,	PUNCT
fnp-3453	354	7	munro	munro	PROPN
fnp-3453	354	8	ca	ca	PROPN
fnp-3453	354	9	,	,	PUNCT
fnp-3453	354	10	ma	ma	PROPN
fnp-3453	354	11	s	s	PROPN
fnp-3453	354	12	,	,	PUNCT
fnp-3453	354	13	yue	yue	PROPN
fnp-3453	354	14	c	c	PROPN
fnp-3453	354	15	,	,	PUNCT
fnp-3453	354	16	chen	chen	PROPN
fnp-3453	354	17	s	s	PART
fnp-3453	354	18	et	et	PROPN
fnp-3453	354	19	al	al	PROPN
fnp-3453	354	20	(	(	PUNCT
fnp-3453	354	21	2015	2015	NUM
fnp-3453	354	22	)	)	PUNCT
fnp-3453	354	23	neuroinflammation	neuroinflammation	NOUN
fnp-3453	354	24	and	and	CCONJ
fnp-3453	354	25	brain	brain	NOUN
fnp-3453	354	26	atrophy	atrophy	NOUN
fnp-3453	354	27	in	in	ADP
fnp-3453	354	28	former	former	ADJ
fnp-3453	354	29	nfl	nfl	PROPN
fnp-3453	354	30	players	player	NOUN
fnp-3453	354	31	:	:	PUNCT
fnp-3453	354	32	an	an	DET
fnp-3453	354	33	in	in	ADP
fnp-3453	354	34	vivo	vivo	ADJ
fnp-3453	354	35	multimodal	multimodal	NOUN
fnp-3453	354	36	imaging	imaging	NOUN
fnp-3453	354	37	pilot	pilot	NOUN
fnp-3453	354	38	study	study	NOUN
fnp-3453	354	39	.	.	PUNCT
fnp-3453	355	1	neurobiol	neurobiol	PROPN
fnp-3453	355	2	dis	dis	PROPN
fnp-3453	355	3	74	74	NUM
fnp-3453	355	4	:	:	PUNCT
fnp-3453	355	5	58	58	NUM
fnp-3453	355	6	-	-	SYM
fnp-3453	355	7	65	65	NUM
fnp-3453	355	8	https://doi.org/10.1016/j.nbd.2014.10.019	https://doi.org/10.1016/j.nbd.2014.10.019	PROPN
fnp-3453	355	9	11	11	NUM
fnp-3453	355	10	.	.	PUNCT
fnp-3453	356	1	ghajari	ghajari	PROPN
fnp-3453	356	2	m	m	PROPN
fnp-3453	356	3	,	,	PUNCT
fnp-3453	356	4	hellyer	hellyer	PROPN
fnp-3453	356	5	pj	pj	PROPN
fnp-3453	356	6	,	,	PUNCT
fnp-3453	356	7	sharp	sharp	ADJ
fnp-3453	356	8	dj	dj	X
fnp-3453	356	9	(	(	PUNCT
fnp-3453	356	10	2017	2017	NUM
fnp-3453	356	11	)	)	PUNCT
fnp-3453	356	12	computational	computational	ADJ
fnp-3453	356	13	modelling	modelling	NOUN
fnp-3453	356	14	of	of	ADP
fnp-3453	356	15	traumatic	traumatic	ADJ
fnp-3453	356	16	brain	brain	NOUN
fnp-3453	356	17	injury	injury	NOUN
fnp-3453	356	18	predicts	predict	VERB
fnp-3453	356	19	the	the	DET
fnp-3453	356	20	location	location	NOUN
fnp-3453	356	21	of	of	ADP
fnp-3453	356	22	chronic	chronic	ADJ
fnp-3453	356	23	traumatic	traumatic	ADJ
fnp-3453	356	24	encephalopathy	encephalopathy	ADJ
fnp-3453	356	25	pathology	pathology	NOUN
fnp-3453	356	26	.	.	PUNCT
fnp-3453	357	1	brain	brain	NOUN
fnp-3453	357	2	140	140	NUM
fnp-3453	357	3	:	:	PUNCT
fnp-3453	357	4	333	333	NUM
fnp-3453	357	5	-	-	SYM
fnp-3453	357	6	343	343	NUM
fnp-3453	357	7	https://doi.org/10.1093/brain/aww317	https://doi.org/10.1093/brain/aww317	NOUN
fnp-3453	357	8	12	12	NUM
fnp-3453	357	9	.	.	PUNCT
fnp-3453	358	1	hardy	hardy	PROPN
fnp-3453	358	2	ja	ja	PROPN
fnp-3453	358	3	,	,	PUNCT
fnp-3453	358	4	higgins	higgins	PROPN
fnp-3453	358	5	ga	ga	PROPN
fnp-3453	358	6	(	(	PUNCT
fnp-3453	358	7	1992	1992	NUM
fnp-3453	358	8	)	)	PUNCT
fnp-3453	358	9	alzheimer	alzheimer	PROPN
fnp-3453	358	10	's	's	PART
fnp-3453	358	11	disease	disease	NOUN
fnp-3453	358	12	:	:	PUNCT
fnp-3453	358	13	the	the	DET
fnp-3453	358	14	amyloid	amyloid	NOUN
fnp-3453	358	15	cascade	cascade	NOUN
fnp-3453	358	16	hypothesis	hypothesis	NOUN
fnp-3453	358	17	.	.	PUNCT
fnp-3453	359	1	science	science	NOUN
fnp-3453	359	2	256	256	NUM
fnp-3453	359	3	:	:	PUNCT
fnp-3453	359	4	184	184	NUM
fnp-3453	359	5	-	-	SYM
fnp-3453	359	6	185	185	NUM
fnp-3453	359	7	https://doi.org/10.1126/science.1566067	https://doi.org/10.1126/science.1566067	ADP
fnp-3453	359	8	13	13	NUM
fnp-3453	359	9	.	.	PUNCT
fnp-3453	360	1	hiebert	hiebert	PROPN
fnp-3453	360	2	jb	jb	PROPN
fnp-3453	360	3	,	,	PUNCT
fnp-3453	360	4	shen	shen	PROPN
fnp-3453	360	5	q	q	PROPN
fnp-3453	360	6	,	,	PUNCT
fnp-3453	360	7	thimmesch	thimmesch	PROPN
fnp-3453	360	8	ar	ar	PROPN
fnp-3453	360	9	,	,	PUNCT
fnp-3453	360	10	pierce	pierce	PROPN
fnp-3453	360	11	jd	jd	PROPN
fnp-3453	360	12	(	(	PUNCT
fnp-3453	360	13	2015	2015	NUM
fnp-3453	360	14	)	)	PUNCT
fnp-3453	360	15	traumatic	traumatic	ADJ
fnp-3453	360	16	brain	brain	NOUN
fnp-3453	360	17	injury	injury	NOUN
fnp-3453	360	18	and	and	CCONJ
fnp-3453	360	19	mitochondrial	mitochondrial	ADJ
fnp-3453	360	20	dysfunction	dysfunction	NOUN
fnp-3453	360	21	.	.	PUNCT
fnp-3453	361	1	am	be	AUX
fnp-3453	361	2	j	j	PROPN
fnp-3453	361	3	med	med	PROPN
fnp-3453	361	4	sci	sci	PROPN
fnp-3453	361	5	350	350	NUM
fnp-3453	361	6	:	:	PUNCT
fnp-3453	361	7	132	132	NUM
fnp-3453	361	8	-	-	SYM
fnp-3453	361	9	138	138	NUM
fnp-3453	361	10	https://doi.org/10.1097/maj.0000000000000506	https://doi.org/10.1097/maj.0000000000000506	NOUN
fnp-3453	361	11	14	14	NUM
fnp-3453	361	12	.	.	PUNCT
fnp-3453	362	1	huber	huber	PROPN
fnp-3453	362	2	w	w	PROPN
fnp-3453	362	3	,	,	PUNCT
fnp-3453	362	4	carey	carey	PROPN
fnp-3453	362	5	vj	vj	PROPN
fnp-3453	362	6	,	,	PUNCT
fnp-3453	362	7	gentleman	gentleman	ADJ
fnp-3453	362	8	r	r	NOUN
fnp-3453	362	9	,	,	PUNCT
fnp-3453	362	10	anders	anders	PROPN
fnp-3453	362	11	s	s	PROPN
fnp-3453	362	12	,	,	PUNCT
fnp-3453	362	13	carlson	carlson	PROPN
fnp-3453	362	14	m	m	PROPN
fnp-3453	362	15	,	,	PUNCT
fnp-3453	362	16	carvalho	carvalho	VERB
fnp-3453	362	17	bs	bs	PROPN
fnp-3453	362	18	et	et	PROPN
fnp-3453	362	19	al	al	PROPN
fnp-3453	362	20	(	(	PUNCT
fnp-3453	362	21	2015	2015	NUM
fnp-3453	362	22	)	)	PUNCT
fnp-3453	362	23	orchestrating	orchestrate	VERB
fnp-3453	362	24	high	high	ADJ
fnp-3453	362	25	-	-	PUNCT
fnp-3453	362	26	throughput	throughput	NOUN
fnp-3453	362	27	genomic	genomic	ADJ
fnp-3453	362	28	analysis	analysis	NOUN
fnp-3453	362	29	with	with	ADP
fnp-3453	362	30	bioconductor	bioconductor	NOUN
fnp-3453	362	31	.	.	PUNCT
fnp-3453	363	1	nat	nat	PROPN
fnp-3453	363	2	methods	method	NOUN
fnp-3453	363	3	12	12	NUM
fnp-3453	363	4	:	:	PUNCT
fnp-3453	363	5	115	115	NUM
fnp-3453	363	6	-	-	SYM
fnp-3453	363	7	121	121	NUM
fnp-3453	363	8	https://doi.org/10.1038/nmeth.3252	https://doi.org/10.1038/nmeth.3252	NOUN
fnp-3453	363	9	15	15	NUM
fnp-3453	363	10	.	.	PUNCT
fnp-3453	364	1	jun	jun	PROPN
fnp-3453	364	2	gr	gr	PROPN
fnp-3453	364	3	,	,	PUNCT
fnp-3453	364	4	you	you	PRON
fnp-3453	364	5	y	y	NOUN
fnp-3453	364	6	,	,	PUNCT
fnp-3453	364	7	zhu	zhu	PROPN
fnp-3453	364	8	c	c	X
fnp-3453	364	9	,	,	PUNCT
fnp-3453	364	10	meng	meng	PROPN
fnp-3453	364	11	g	g	PROPN
fnp-3453	364	12	,	,	PUNCT
fnp-3453	364	13	chung	chung	PROPN
fnp-3453	364	14	j	j	PROPN
fnp-3453	364	15	,	,	PUNCT
fnp-3453	364	16	panitch	panitch	PROPN
fnp-3453	364	17	r	r	NOUN
fnp-3453	364	18	et	et	NOUN
fnp-3453	364	19	al	al	PROPN
fnp-3453	364	20	(	(	PUNCT
fnp-3453	364	21	2020	2020	NUM
fnp-3453	364	22	)	)	PUNCT
fnp-3453	364	23	protein	protein	NOUN
fnp-3453	364	24	phosphatase	phosphatase	NOUN
fnp-3453	364	25	2a	2a	NUM
fnp-3453	364	26	,	,	PUNCT
fnp-3453	364	27	complement	complement	NOUN
fnp-3453	364	28	component	component	NOUN
fnp-3453	364	29	4	4	NUM
fnp-3453	364	30	,	,	PUNCT
fnp-3453	364	31	and	and	CCONJ
fnp-3453	364	32	apoe	apoe	ADJ
fnp-3453	364	33	genotype	genotype	NOUN
fnp-3453	364	34	linked	link	VERB
fnp-3453	364	35	to	to	ADP
fnp-3453	364	36	alzheimer	alzheimer	PROPN
fnp-3453	364	37	’s	’s	PART
fnp-3453	364	38	disease	disease	NOUN
fnp-3453	364	39	using	use	VERB
fnp-3453	364	40	a	a	DET
fnp-3453	364	41	systems	system	NOUN
fnp-3453	364	42	biology	biology	NOUN
fnp-3453	364	43	approach	approach	NOUN
fnp-3453	364	44	.	.	PUNCT
fnp-3453	365	1	medrxiv	medrxiv	X
fnp-3453	365	2	:	:	PUNCT
fnp-3453	365	3	https://doi.org/10.1101/2020.11.20.20235051	https://doi.org/10.1101/2020.11.20.20235051	PROPN
fnp-3453	365	4	16	16	NUM
fnp-3453	365	5	.	.	PUNCT
fnp-3453	366	1	karran	karran	PROPN
fnp-3453	366	2	e	e	PROPN
fnp-3453	366	3	,	,	PUNCT
fnp-3453	366	4	mercken	mercken	VERB
fnp-3453	366	5	m	m	PROPN
fnp-3453	366	6	,	,	PUNCT
fnp-3453	366	7	de	de	PROPN
fnp-3453	366	8	strooper	strooper	NOUN
fnp-3453	366	9	b	b	PROPN
fnp-3453	366	10	(	(	PUNCT
fnp-3453	366	11	2011	2011	NUM
fnp-3453	366	12	)	)	PUNCT
fnp-3453	366	13	the	the	DET
fnp-3453	366	14	amyloid	amyloid	NOUN
fnp-3453	366	15	cascade	cascade	NOUN
fnp-3453	366	16	hypothesis	hypothesis	NOUN
fnp-3453	366	17	for	for	ADP
fnp-3453	366	18	alzheimer	alzheimer	PROPN
fnp-3453	366	19	's	's	PART
fnp-3453	366	20	disease	disease	NOUN
fnp-3453	366	21	:	:	PUNCT
fnp-3453	366	22	an	an	DET
fnp-3453	366	23	appraisal	appraisal	NOUN
fnp-3453	366	24	for	for	ADP
fnp-3453	366	25	the	the	DET
fnp-3453	366	26	development	development	NOUN
fnp-3453	366	27	of	of	ADP
fnp-3453	366	28	therapeutics	therapeutic	NOUN
fnp-3453	366	29	.	.	PUNCT
fnp-3453	367	1	nat	nat	PROPN
fnp-3453	367	2	rev	rev	VERB
fnp-3453	367	3	drug	drug	PROPN
fnp-3453	367	4	discov	discov	PROPN
fnp-3453	367	5	10	10	NUM
fnp-3453	367	6	:	:	PUNCT
fnp-3453	367	7	698	698	NUM
fnp-3453	367	8	-	-	SYM
fnp-3453	367	9	712	712	NUM
fnp-3453	367	10	https://doi.org/10.1038/nrd3505	https://doi.org/10.1038/nrd3505	NUM
fnp-3453	367	11	17	17	NUM
fnp-3453	367	12	.	.	PUNCT
fnp-3453	368	1	labadorf	labadorf	PROPN
fnp-3453	368	2	a	a	PRON
fnp-3453	368	3	,	,	PUNCT
fnp-3453	368	4	choi	choi	PROPN
fnp-3453	368	5	sh	sh	PROPN
fnp-3453	368	6	,	,	PUNCT
fnp-3453	368	7	myers	myers	PROPN
fnp-3453	368	8	rh	rh	PROPN
fnp-3453	368	9	(	(	PUNCT
fnp-3453	368	10	2017	2017	NUM
fnp-3453	368	11	)	)	PUNCT
fnp-3453	368	12	evidence	evidence	NOUN
fnp-3453	368	13	for	for	ADP
fnp-3453	368	14	a	a	DET
fnp-3453	368	15	pan	pan	ADJ
fnp-3453	368	16	-	-	ADJ
fnp-3453	368	17	neurodegenerative	neurodegenerative	ADJ
fnp-3453	368	18	disease	disease	NOUN
fnp-3453	368	19	response	response	NOUN
fnp-3453	368	20	in	in	ADP
fnp-3453	368	21	huntington	huntington	PROPN
fnp-3453	368	22	's	's	PART
fnp-3453	368	23	and	and	CCONJ
fnp-3453	368	24	parkinson	parkinson	NOUN
fnp-3453	368	25	's	's	PART
fnp-3453	368	26	disease	disease	NOUN
fnp-3453	368	27	expression	expression	NOUN
fnp-3453	368	28	profiles	profile	NOUN
fnp-3453	368	29	.	.	PUNCT
fnp-3453	369	1	front	front	NOUN
fnp-3453	369	2	mol	mol	ADP
fnp-3453	369	3	neurosci	neurosci	PROPN
fnp-3453	369	4	10	10	NUM
fnp-3453	369	5	:	:	SYM
fnp-3453	369	6	430	430	NUM
fnp-3453	369	7	https://doi.org/10.3389/fnmol.2017.00430	https://doi.org/10.3389/fnmol.2017.00430	PROPN
fnp-3453	369	8	18	18	NUM
fnp-3453	369	9	.	.	PUNCT
fnp-3453	369	10	love	love	PROPN
fnp-3453	369	11	mi	mi	PROPN
fnp-3453	369	12	,	,	PUNCT
fnp-3453	369	13	huber	huber	PROPN
fnp-3453	369	14	w	w	PROPN
fnp-3453	369	15	,	,	PUNCT
fnp-3453	369	16	anders	anders	PROPN
fnp-3453	369	17	s	s	X
fnp-3453	369	18	(	(	PUNCT
fnp-3453	369	19	2014	2014	NUM
fnp-3453	369	20	)	)	PUNCT
fnp-3453	369	21	moderated	moderated	ADJ
fnp-3453	369	22	estimation	estimation	NOUN
fnp-3453	369	23	of	of	ADP
fnp-3453	369	24	fold	fold	ADJ
fnp-3453	369	25	change	change	NOUN
fnp-3453	369	26	and	and	CCONJ
fnp-3453	369	27	dispersion	dispersion	NOUN
fnp-3453	369	28	for	for	ADP
fnp-3453	369	29	rna	rna	NOUN
fnp-3453	369	30	-	-	PUNCT
fnp-3453	369	31	seq	seq	NOUN
fnp-3453	369	32	data	datum	NOUN
fnp-3453	369	33	with	with	ADP
fnp-3453	369	34	deseq2	deseq2	PROPN
fnp-3453	369	35	.	.	PUNCT
fnp-3453	370	1	genome	genome	NOUN
fnp-3453	370	2	biol	biol	NOUN
fnp-3453	370	3	15	15	NUM
fnp-3453	370	4	:	:	PUNCT
fnp-3453	370	5	550	550	NUM
fnp-3453	370	6	https://doi.org/10.1186/s13059-014-0550-8	https://doi.org/10.1186/s13059-014-0550-8	NUM
fnp-3453	370	7	19	19	NUM
fnp-3453	370	8	.	.	PUNCT
fnp-3453	371	1	love	love	PROPN
fnp-3453	371	2	s	s	PROPN
fnp-3453	371	3	,	,	PUNCT
fnp-3453	371	4	louis	louis	PROPN
fnp-3453	371	5	d	d	PROPN
fnp-3453	371	6	,	,	PUNCT
fnp-3453	371	7	ellison	ellison	PROPN
fnp-3453	371	8	dw	dw	PROPN
fnp-3453	371	9	(	(	PUNCT
fnp-3453	371	10	2008	2008	NUM
fnp-3453	371	11	)	)	PUNCT
fnp-3453	371	12	greenfield	greenfield	NOUN
fnp-3453	371	13	’s	’s	PART
fnp-3453	371	14	neuropathology	neuropathology	NOUN
fnp-3453	371	15	,	,	PUNCT
fnp-3453	371	16	2	2	NUM
fnp-3453	371	17	-	-	PUNCT
fnp-3453	371	18	volume	volume	NOUN
fnp-3453	371	19	set	set	NOUN
fnp-3453	371	20	.	.	PUNCT
fnp-3453	372	1	crc	crc	PROPN
fnp-3453	372	2	press	press	PROPN
fnp-3453	372	3	20	20	NUM
fnp-3453	372	4	.	.	PUNCT
fnp-3453	373	1	mackenzie	mackenzie	PROPN
fnp-3453	373	2	ir	ir	PROPN
fnp-3453	373	3	,	,	PUNCT
fnp-3453	373	4	neumann	neumann	PROPN
fnp-3453	373	5	m	m	PROPN
fnp-3453	373	6	,	,	PUNCT
fnp-3453	373	7	bigio	bigio	NOUN
fnp-3453	373	8	eh	eh	INTJ
fnp-3453	373	9	,	,	PUNCT
fnp-3453	373	10	cairns	cairns	PROPN
fnp-3453	373	11	nj	nj	PROPN
fnp-3453	373	12	,	,	PUNCT
fnp-3453	373	13	alafuzoff	alafuzoff	NOUN
fnp-3453	374	1	i	i	PRON
fnp-3453	374	2	,	,	PUNCT
fnp-3453	374	3	kril	kril	PROPN
fnp-3453	374	4	j	j	PROPN
fnp-3453	374	5	et	et	PROPN
fnp-3453	374	6	al	al	PROPN
fnp-3453	374	7	(	(	PUNCT
fnp-3453	374	8	2010	2010	NUM
fnp-3453	374	9	)	)	PUNCT
fnp-3453	374	10	nomenclature	nomenclature	NOUN
fnp-3453	374	11	and	and	CCONJ
fnp-3453	374	12	nosology	nosology	NOUN
fnp-3453	374	13	for	for	ADP
fnp-3453	374	14	neuropathologic	neuropathologic	ADJ
fnp-3453	374	15	subtypes	subtype	NOUN
fnp-3453	374	16	of	of	ADP
fnp-3453	374	17	frontotemporal	frontotemporal	ADJ
fnp-3453	374	18	lobar	lobar	ADJ
fnp-3453	374	19	degeneration	degeneration	NOUN
fnp-3453	374	20	:	:	PUNCT
fnp-3453	374	21	an	an	DET
fnp-3453	374	22	update	update	NOUN
fnp-3453	374	23	.	.	PUNCT
fnp-3453	375	1	acta	acta	PROPN
fnp-3453	375	2	neuropathol	neuropathol	PROPN
fnp-3453	375	3	119	119	NUM
fnp-3453	375	4	:	:	SYM
fnp-3453	375	5	1	1	NUM
fnp-3453	375	6	-	-	SYM
fnp-3453	375	7	4	4	NUM
fnp-3453	375	8	https://doi.org/10.1007/s00401-009-0612-2	https://doi.org/10.1007/s00401-009-0612-2	NUM
fnp-3453	375	9	21	21	NUM
fnp-3453	375	10	.	.	PUNCT
fnp-3453	376	1	mckee	mckee	PROPN
fnp-3453	376	2	ac	ac	PROPN
fnp-3453	376	3	,	,	PUNCT
fnp-3453	376	4	cairns	cairns	PROPN
fnp-3453	376	5	nj	nj	PROPN
fnp-3453	376	6	,	,	PUNCT
fnp-3453	376	7	dickson	dickson	PROPN
fnp-3453	376	8	dw	dw	PROPN
fnp-3453	376	9	,	,	PUNCT
fnp-3453	376	10	folkerth	folkerth	PROPN
fnp-3453	376	11	rd	rd	PROPN
fnp-3453	376	12	,	,	PUNCT
fnp-3453	376	13	dirk	dirk	PROPN
fnp-3453	376	14	keene	keene	PROPN
fnp-3453	376	15	c	c	AUX
fnp-3453	376	16	,	,	PUNCT
fnp-3453	376	17	litvan	litvan	NOUN
fnp-3453	376	18	i	i	PRON
fnp-3453	376	19	et	et	VERB
fnp-3453	376	20	al	al	PROPN
fnp-3453	376	21	(	(	PUNCT
fnp-3453	376	22	2016	2016	NUM
fnp-3453	376	23	)	)	PUNCT
fnp-3453	376	24	the	the	DET
fnp-3453	376	25	first	first	ADJ
fnp-3453	376	26	ninds	nind	NOUN
fnp-3453	376	27	/	/	SYM
fnp-3453	376	28	nibib	nibib	NOUN
fnp-3453	376	29	consensus	consensus	NOUN
fnp-3453	376	30	meeting	meeting	NOUN
fnp-3453	376	31	to	to	PART
fnp-3453	376	32	define	define	VERB
fnp-3453	376	33	neuropathological	neuropathological	ADJ
fnp-3453	376	34	criteria	criterion	NOUN
fnp-3453	376	35	for	for	ADP
fnp-3453	376	36	the	the	DET
fnp-3453	376	37	diagnosis	diagnosis	NOUN
fnp-3453	376	38	of	of	ADP
fnp-3453	376	39	chronic	chronic	ADJ
fnp-3453	376	40	traumatic	traumatic	ADJ
fnp-3453	376	41	encephalopathy	encephalopathy	NOUN
fnp-3453	376	42	.	.	PUNCT
fnp-3453	377	1	acta	acta	PROPN
fnp-3453	377	2	neuropathol	neuropathol	PROPN
fnp-3453	377	3	131	131	NUM
fnp-3453	377	4	:	:	PUNCT
fnp-3453	377	5	75	75	NUM
fnp-3453	377	6	-	-	SYM
fnp-3453	377	7	86	86	NUM
fnp-3453	377	8	https://doi.org/10.1007/s00401-015-1515-z	https://doi.org/10.1007/s00401-015-1515-z	NOUN
fnp-3453	377	9	22	22	NUM
fnp-3453	377	10	.	.	PUNCT
fnp-3453	378	1	mckee	mckee	PROPN
fnp-3453	378	2	ac	ac	PROPN
fnp-3453	378	3	,	,	PUNCT
fnp-3453	378	4	cantu	cantu	PROPN
fnp-3453	378	5	rc	rc	PROPN
fnp-3453	378	6	,	,	PUNCT
fnp-3453	378	7	nowinski	nowinski	PROPN
fnp-3453	378	8	cj	cj	PROPN
fnp-3453	378	9	,	,	PUNCT
fnp-3453	378	10	hedley	hedley	PROPN
fnp-3453	378	11	-	-	PUNCT
fnp-3453	378	12	whyte	whyte	PROPN
fnp-3453	378	13	et	et	PROPN
fnp-3453	378	14	,	,	PUNCT
fnp-3453	378	15	gavett	gavett	PROPN
fnp-3453	378	16	be	be	PROPN
fnp-3453	378	17	,	,	PUNCT
fnp-3453	378	18	budson	budson	NOUN
fnp-3453	378	19	ae	ae	PROPN
fnp-3453	378	20	et	et	PROPN
fnp-3453	378	21	al	al	PROPN
fnp-3453	378	22	(	(	PUNCT
fnp-3453	378	23	2009	2009	NUM
fnp-3453	378	24	)	)	PUNCT
fnp-3453	378	25	chronic	chronic	ADJ
fnp-3453	378	26	traumatic	traumatic	ADJ
fnp-3453	378	27	encephalopathy	encephalopathy	NOUN
fnp-3453	378	28	in	in	ADP
fnp-3453	378	29	athletes	athlete	NOUN
fnp-3453	378	30	:	:	PUNCT
fnp-3453	378	31	progressive	progressive	ADJ
fnp-3453	378	32	tauopathy	tauopathy	NOUN
fnp-3453	378	33	after	after	ADP
fnp-3453	378	34	repetitive	repetitive	ADJ
fnp-3453	378	35	head	head	NOUN
fnp-3453	378	36	injury	injury	NOUN
fnp-3453	378	37	.	.	PUNCT
fnp-3453	379	1	j	j	PROPN
fnp-3453	379	2	neuropathol	neuropathol	PROPN
fnp-3453	379	3	exp	exp	PROPN
fnp-3453	379	4	neurol	neurol	PROPN
fnp-3453	379	5	68	68	NUM
fnp-3453	379	6	:	:	PUNCT
fnp-3453	379	7	709	709	NUM
fnp-3453	379	8	-	-	SYM
fnp-3453	379	9	735	735	NUM
fnp-3453	379	10	https://doi.org/10.1097/nen.0b013e3181a9d503	https://doi.org/10.1097/nen.0b013e3181a9d503	NOUN
fnp-3453	379	11	23	23	NUM
fnp-3453	379	12	.	.	PUNCT
fnp-3453	380	1	mckee	mckee	PROPN
fnp-3453	380	2	ac	ac	PROPN
fnp-3453	380	3	,	,	PUNCT
fnp-3453	380	4	daneshvar	daneshvar	PROPN
fnp-3453	380	5	dh	dh	PROPN
fnp-3453	380	6	,	,	PUNCT
fnp-3453	380	7	alvarez	alvarez	PROPN
fnp-3453	380	8	ve	ve	PROPN
fnp-3453	380	9	,	,	PUNCT
fnp-3453	380	10	stein	stein	PROPN
fnp-3453	380	11	td	td	PROPN
fnp-3453	380	12	(	(	PUNCT
fnp-3453	380	13	2014	2014	NUM
fnp-3453	380	14	)	)	PUNCT
fnp-3453	380	15	the	the	DET
fnp-3453	380	16	neuropathology	neuropathology	NOUN
fnp-3453	380	17	of	of	ADP
fnp-3453	380	18	sport	sport	NOUN
fnp-3453	380	19	.	.	PUNCT
fnp-3453	381	1	acta	acta	PROPN
fnp-3453	381	2	neuropathol	neuropathol	PROPN
fnp-3453	381	3	127	127	NUM
fnp-3453	381	4	:	:	PUNCT
fnp-3453	381	5	29	29	NUM
fnp-3453	381	6	-	-	SYM
fnp-3453	381	7	51	51	NUM
fnp-3453	381	8	https://doi.org/10.1007/s00401-013-1230-6	https://doi.org/10.1007/s00401-013-1230-6	NUM
fnp-3453	381	9	24	24	NUM
fnp-3453	381	10	.	.	PUNCT
fnp-3453	382	1	mckee	mckee	PROPN
fnp-3453	382	2	ac	ac	PROPN
fnp-3453	382	3	,	,	PUNCT
fnp-3453	382	4	stern	stern	PROPN
fnp-3453	382	5	ra	ra	PROPN
fnp-3453	382	6	,	,	PUNCT
fnp-3453	382	7	nowinski	nowinski	PROPN
fnp-3453	382	8	cj	cj	PROPN
fnp-3453	382	9	,	,	PUNCT
fnp-3453	382	10	stein	stein	PROPN
fnp-3453	382	11	td	td	PROPN
fnp-3453	382	12	,	,	PUNCT
fnp-3453	382	13	alvarez	alvarez	PROPN
fnp-3453	382	14	ve	ve	PROPN
fnp-3453	382	15	,	,	PUNCT
fnp-3453	382	16	daneshvar	daneshvar	PROPN
fnp-3453	382	17	dh	dh	NOUN
fnp-3453	382	18	et	et	PROPN
fnp-3453	382	19	al	al	PROPN
fnp-3453	382	20	(	(	PUNCT
fnp-3453	382	21	2013	2013	NUM
fnp-3453	382	22	)	)	PUNCT
fnp-3453	382	23	the	the	DET
fnp-3453	382	24	spectrum	spectrum	NOUN
fnp-3453	382	25	of	of	ADP
fnp-3453	382	26	disease	disease	NOUN
fnp-3453	382	27	in	in	ADP
fnp-3453	382	28	chronic	chronic	ADJ
fnp-3453	382	29	traumatic	traumatic	ADJ
fnp-3453	382	30	encephalopathy	encephalopathy	NOUN
fnp-3453	382	31	.	.	PUNCT
fnp-3453	383	1	brain	brain	NOUN
fnp-3453	383	2	136	136	NUM
fnp-3453	383	3	:	:	PUNCT
fnp-3453	383	4	43	43	NUM
fnp-3453	383	5	-	-	SYM
fnp-3453	383	6	64	64	NUM
fnp-3453	383	7	https://doi.org/10.1093/brain/aws307	https://doi.org/10.1093/brain/aws307	NUM
fnp-3453	383	8	25	25	NUM
fnp-3453	383	9	.	.	PUNCT
fnp-3453	384	1	mckeith	mckeith	PROPN
fnp-3453	384	2	ig	ig	PROPN
fnp-3453	384	3	(	(	PUNCT
fnp-3453	384	4	2006	2006	NUM
fnp-3453	384	5	)	)	PUNCT
fnp-3453	384	6	consensus	consensus	NOUN
fnp-3453	384	7	guidelines	guideline	NOUN
fnp-3453	384	8	for	for	ADP
fnp-3453	384	9	the	the	DET
fnp-3453	384	10	clinical	clinical	ADJ
fnp-3453	384	11	and	and	CCONJ
fnp-3453	384	12	pathologic	pathologic	ADJ
fnp-3453	384	13	diagnosis	diagnosis	NOUN
fnp-3453	384	14	of	of	ADP
fnp-3453	384	15	dementia	dementia	NOUN
fnp-3453	384	16	with	with	ADP
fnp-3453	384	17	lewy	lewy	ADJ
fnp-3453	384	18	bodies	body	NOUN
fnp-3453	384	19	(	(	PUNCT
fnp-3453	384	20	dlb	dlb	NOUN
fnp-3453	384	21	):	):	PUNCT
fnp-3453	384	22	report	report	NOUN
fnp-3453	384	23	of	of	ADP
fnp-3453	384	24	the	the	DET
fnp-3453	384	25	consortium	consortium	NOUN
fnp-3453	384	26	on	on	ADP
fnp-3453	384	27	dlb	dlb	PROPN
fnp-3453	384	28	international	international	ADJ
fnp-3453	384	29	workshop	workshop	NOUN
fnp-3453	384	30	.	.	PUNCT
fnp-3453	385	1	j	j	PROPN
fnp-3453	385	2	alzheimers	alzheimers	PROPN
fnp-3453	385	3	dis	dis	PROPN
fnp-3453	385	4	9	9	NUM
fnp-3453	385	5	:	:	PUNCT
fnp-3453	385	6	417	417	NUM
fnp-3453	385	7	-	-	SYM
fnp-3453	385	8	423	423	NUM
fnp-3453	385	9	.	.	PUNCT
fnp-3453	386	1	https://doi.org/10.3233/jad-2006-9s347	https://doi.org/10.3233/jad-2006-9s347	PROPN
fnp-3453	386	2	26	26	NUM
fnp-3453	386	3	.	.	PUNCT
fnp-3453	387	1	montine	montine	PROPN
fnp-3453	387	2	tj	tj	PROPN
fnp-3453	387	3	,	,	PUNCT
fnp-3453	387	4	phelps	phelps	PROPN
fnp-3453	387	5	ch	ch	PROPN
fnp-3453	387	6	,	,	PUNCT
fnp-3453	387	7	beach	beach	PROPN
fnp-3453	387	8	tg	tg	PROPN
fnp-3453	387	9	,	,	PUNCT
fnp-3453	387	10	bigio	bigio	NOUN
fnp-3453	387	11	eh	eh	INTJ
fnp-3453	387	12	,	,	PUNCT
fnp-3453	387	13	cairns	cairns	PROPN
fnp-3453	387	14	nj	nj	PROPN
fnp-3453	387	15	,	,	PUNCT
fnp-3453	387	16	dickson	dickson	PROPN
fnp-3453	387	17	dw	dw	PROPN
fnp-3453	387	18	et	et	PROPN
fnp-3453	387	19	al	al	PROPN
fnp-3453	387	20	(	(	PUNCT
fnp-3453	387	21	2012	2012	NUM
fnp-3453	387	22	)	)	PUNCT
fnp-3453	387	23	national	national	PROPN
fnp-3453	387	24	institute	institute	NOUN
fnp-3453	387	25	on	on	ADP
fnp-3453	387	26	aging	age	VERB
fnp-3453	387	27	-	-	PUNCT
fnp-3453	387	28	alzheimer	alzheimer	NOUN
fnp-3453	387	29	's	's	PART
fnp-3453	387	30	association	association	NOUN
fnp-3453	387	31	guidelines	guideline	NOUN
fnp-3453	387	32	for	for	ADP
fnp-3453	387	33	the	the	DET
fnp-3453	387	34	neuropathologic	neuropathologic	ADJ
fnp-3453	387	35	assessment	assessment	NOUN
fnp-3453	387	36	of	of	ADP
fnp-3453	387	37	alzheimer	alzheimer	PROPN
fnp-3453	387	38	's	's	PART
fnp-3453	387	39	disease	disease	NOUN
fnp-3453	387	40	:	:	PUNCT
fnp-3453	387	41	a	a	DET
fnp-3453	387	42	practical	practical	ADJ
fnp-3453	387	43	approach	approach	NOUN
fnp-3453	387	44	.	.	PUNCT
fnp-3453	388	1	acta	acta	PROPN
fnp-3453	388	2	neuropathol	neuropathol	PROPN
fnp-3453	388	3	123	123	NUM
fnp-3453	388	4	:	:	PUNCT
fnp-3453	388	5	1	1	NUM
fnp-3453	388	6	-	-	SYM
fnp-3453	388	7	11	11	NUM
fnp-3453	388	8	https://doi.org/10.1007/s00401-011-0910-3	https://doi.org/10.1007/s00401-011-0910-3	NUM
fnp-3453	388	9	27	27	NUM
fnp-3453	388	10	.	.	PUNCT
fnp-3453	389	1	schartz	schartz	PROPN
fnp-3453	389	2	nd	nd	PROPN
fnp-3453	389	3	,	,	PUNCT
fnp-3453	389	4	tenner	tenner	PROPN
fnp-3453	389	5	aj	aj	PROPN
fnp-3453	389	6	(	(	PUNCT
fnp-3453	389	7	2020	2020	NUM
fnp-3453	389	8	)	)	PUNCT
fnp-3453	389	9	the	the	DET
fnp-3453	389	10	good	good	NOUN
fnp-3453	389	11	,	,	PUNCT
fnp-3453	389	12	the	the	DET
fnp-3453	389	13	bad	bad	ADJ
fnp-3453	389	14	,	,	PUNCT
fnp-3453	389	15	and	and	CCONJ
fnp-3453	389	16	the	the	DET
fnp-3453	389	17	opportunities	opportunity	NOUN
fnp-3453	389	18	of	of	ADP
fnp-3453	389	19	the	the	DET
fnp-3453	389	20	complement	complement	NOUN
fnp-3453	389	21	system	system	NOUN
fnp-3453	389	22	in	in	ADP
fnp-3453	389	23	neurodegenerative	neurodegenerative	ADJ
fnp-3453	389	24	disease	disease	NOUN
fnp-3453	389	25	.	.	PUNCT
fnp-3453	390	1	j	j	PROPN
fnp-3453	390	2	neuroinflammation	neuroinflammation	NOUN
fnp-3453	390	3	17	17	NUM
fnp-3453	390	4	:	:	PUNCT
fnp-3453	390	5	354	354	NUM
fnp-3453	390	6	https://doi.org/10.1186/s12974-020-02024-8	https://doi.org/10.1186/s12974-020-02024-8	NUM
fnp-3453	390	7	28	28	NUM
fnp-3453	390	8	.	.	PUNCT
fnp-3453	391	1	sekar	sekar	PROPN
fnp-3453	391	2	a	a	PROPN
fnp-3453	391	3	,	,	PUNCT
fnp-3453	391	4	bialas	bialas	PROPN
fnp-3453	391	5	ar	ar	PROPN
fnp-3453	391	6	,	,	PUNCT
fnp-3453	391	7	de	de	PROPN
fnp-3453	391	8	rivera	rivera	PROPN
fnp-3453	391	9	h	h	PROPN
fnp-3453	391	10	,	,	PUNCT
fnp-3453	391	11	davis	davis	PROPN
fnp-3453	391	12	a	a	PRON
fnp-3453	391	13	,	,	PUNCT
fnp-3453	391	14	hammond	hammond	PROPN
fnp-3453	391	15	tr	tr	VERB
fnp-3453	391	16	,	,	PUNCT
fnp-3453	391	17	kamitaki	kamitaki	PROPN
fnp-3453	391	18	n	n	ADP
fnp-3453	391	19	et	et	PROPN
fnp-3453	391	20	al	al	PROPN
fnp-3453	391	21	(	(	PUNCT
fnp-3453	391	22	2016	2016	NUM
fnp-3453	391	23	)	)	PUNCT
fnp-3453	391	24	schizophrenia	schizophrenia	NOUN
fnp-3453	391	25	risk	risk	NOUN
fnp-3453	391	26	from	from	ADP
fnp-3453	391	27	complex	complex	ADJ
fnp-3453	391	28	variation	variation	NOUN
fnp-3453	391	29	of	of	ADP
fnp-3453	391	30	complement	complement	NOUN
fnp-3453	391	31	component	component	NOUN
fnp-3453	391	32	4	4	NUM
fnp-3453	391	33	.	.	PUNCT
fnp-3453	391	34	nature	nature	NOUN
fnp-3453	391	35	530	530	NUM
fnp-3453	391	36	:	:	PUNCT
fnp-3453	391	37	177	177	NUM
fnp-3453	391	38	-	-	SYM
fnp-3453	391	39	183	183	NUM
fnp-3453	391	40	https://doi.org/10.1038/nature16549	https://doi.org/10.1038/nature16549	NOUN
fnp-3453	391	41	29	29	NUM
fnp-3453	391	42	.	.	PUNCT
fnp-3453	392	1	sergushichev	sergushichev	VERB
fnp-3453	392	2	aa	aa	PROPN
fnp-3453	392	3	(	(	PUNCT
fnp-3453	392	4	2016	2016	NUM
fnp-3453	392	5	)	)	PUNCT
fnp-3453	392	6	an	an	DET
fnp-3453	392	7	algorithm	algorithm	NOUN
fnp-3453	392	8	for	for	ADP
fnp-3453	392	9	fast	fast	ADJ
fnp-3453	392	10	preranked	preranke	VERB
fnp-3453	392	11	gene	gene	NOUN
fnp-3453	392	12	set	set	VERB
fnp-3453	392	13	enrichment	enrichment	NOUN
fnp-3453	392	14	analysis	analysis	NOUN
fnp-3453	392	15	using	use	VERB
fnp-3453	392	16	cumulative	cumulative	ADJ
fnp-3453	392	17	statistic	statistic	ADJ
fnp-3453	392	18	calculation	calculation	NOUN
fnp-3453	392	19	.	.	PUNCT
fnp-3453	393	1	biorxiv	biorxiv	NOUN
fnp-3453	393	2	:	:	PUNCT
fnp-3453	394	1	https://doi.org/doi.org/10.1101/060012	https://doi.org/doi.org/10.1101/060012	PROPN
fnp-3453	394	2	30	30	NUM
fnp-3453	394	3	.	.	PUNCT
fnp-3453	394	4	stern	stern	PROPN
fnp-3453	394	5	ra	ra	PROPN
fnp-3453	394	6	,	,	PUNCT
fnp-3453	394	7	daneshvar	daneshvar	PROPN
fnp-3453	394	8	dh	dh	PROPN
fnp-3453	394	9	,	,	PUNCT
fnp-3453	394	10	baugh	baugh	PROPN
fnp-3453	394	11	cm	cm	PROPN
fnp-3453	394	12	,	,	PUNCT
fnp-3453	394	13	seichepine	seichepine	PROPN
fnp-3453	394	14	dr	dr	PROPN
fnp-3453	394	15	,	,	PUNCT
fnp-3453	394	16	montenigro	montenigro	ADJ
fnp-3453	394	17	ph	ph	VERB
fnp-3453	394	18	,	,	PUNCT
fnp-3453	394	19	riley	riley	PROPN
fnp-3453	394	20	do	do	AUX
fnp-3453	394	21	et	et	PROPN
fnp-3453	394	22	al	al	PROPN
fnp-3453	394	23	(	(	PUNCT
fnp-3453	394	24	2013	2013	NUM
fnp-3453	394	25	)	)	PUNCT
fnp-3453	394	26	clinical	clinical	ADJ
fnp-3453	394	27	presentation	presentation	NOUN
fnp-3453	394	28	of	of	ADP
fnp-3453	394	29	chronic	chronic	ADJ
fnp-3453	394	30	traumatic	traumatic	ADJ
fnp-3453	394	31	encephalopathy	encephalopathy	NOUN
fnp-3453	394	32	.	.	PUNCT
fnp-3453	395	1	neurology	neurology	NOUN
fnp-3453	395	2	81	81	NUM
fnp-3453	395	3	:	:	SYM
fnp-3453	395	4	1122	1122	NUM
fnp-3453	395	5	-	-	SYM
fnp-3453	395	6	1129	1129	NUM
fnp-3453	395	7	https://doi.org/10.1212/wnl.0b013e3182a55f7f	https://doi.org/10.1212/wnl.0b013e3182a55f7f	PROPN
fnp-3453	395	8	31	31	NUM
fnp-3453	395	9	.	.	PUNCT
fnp-3453	396	1	szu	szu	PROPN
fnp-3453	396	2	ji	ji	PROPN
fnp-3453	396	3	,	,	PUNCT
fnp-3453	396	4	chaturvedi	chaturvedi	PROPN
fnp-3453	396	5	s	s	PROPN
fnp-3453	396	6	,	,	PUNCT
fnp-3453	396	7	patel	patel	PROPN
fnp-3453	396	8	dd	dd	PROPN
fnp-3453	396	9	,	,	PUNCT
fnp-3453	396	10	binder	binder	NOUN
fnp-3453	396	11	dk	dk	PROPN
fnp-3453	396	12	(	(	PUNCT
fnp-3453	396	13	2020	2020	NUM
fnp-3453	396	14	)	)	PUNCT
fnp-3453	396	15	aquaporin-4	aquaporin-4	NUM
fnp-3453	396	16	dysregulation	dysregulation	NOUN
fnp-3453	396	17	in	in	ADP
fnp-3453	396	18	a	a	DET
fnp-3453	396	19	controlled	control	VERB
fnp-3453	396	20	cortical	cortical	ADJ
fnp-3453	396	21	impact	impact	NOUN
fnp-3453	396	22	injury	injury	NOUN
fnp-3453	396	23	model	model	NOUN
fnp-3453	396	24	of	of	ADP
fnp-3453	396	25	posttraumatic	posttraumatic	ADJ
fnp-3453	396	26	epilepsy	epilepsy	NOUN
fnp-3453	396	27	.	.	PUNCT
fnp-3453	397	1	neuroscience	neuroscience	NOUN
fnp-3453	397	2	428	428	NUM
fnp-3453	397	3	:	:	PUNCT
fnp-3453	397	4	140	140	NUM
fnp-3453	397	5	-	-	SYM
fnp-3453	397	6	153	153	NUM
fnp-3453	397	7	https://doi.org/10.1016/j.neuroscience.2019.12.006	https://doi.org/10.1016/j.neuroscience.2019.12.006	PROPN
fnp-3453	397	8	32	32	NUM
fnp-3453	397	9	.	.	PUNCT
fnp-3453	398	1	tagge	tagge	NOUN
fnp-3453	398	2	ca	ca	PROPN
fnp-3453	398	3	,	,	PUNCT
fnp-3453	398	4	fisher	fisher	PROPN
fnp-3453	398	5	am	be	AUX
fnp-3453	398	6	,	,	PUNCT
fnp-3453	398	7	minaeva	minaeva	VERB
fnp-3453	398	8	ov	ov	PROPN
fnp-3453	398	9	,	,	PUNCT
fnp-3453	398	10	gaudreau	gaudreau	PROPN
fnp-3453	398	11	-	-	PUNCT
fnp-3453	398	12	balderrama	balderrama	PROPN
fnp-3453	398	13	a	a	NOUN
fnp-3453	398	14	,	,	PUNCT
fnp-3453	398	15	moncaster	moncaster	NOUN
fnp-3453	398	16	ja	ja	PROPN
fnp-3453	398	17	,	,	PUNCT
fnp-3453	398	18	zhang	zhang	PROPN
fnp-3453	398	19	xl	xl	PROPN
fnp-3453	398	20	et	et	PROPN
fnp-3453	398	21	al	al	PROPN
fnp-3453	398	22	(	(	PUNCT
fnp-3453	398	23	2018	2018	NUM
fnp-3453	398	24	)	)	PUNCT
fnp-3453	398	25	concussion	concussion	NOUN
fnp-3453	398	26	,	,	PUNCT
fnp-3453	398	27	microvascular	microvascular	ADJ
fnp-3453	398	28	injury	injury	NOUN
fnp-3453	398	29	,	,	PUNCT
fnp-3453	398	30	and	and	CCONJ
fnp-3453	398	31	early	early	ADJ
fnp-3453	398	32	tauopathy	tauopathy	NOUN
fnp-3453	398	33	in	in	ADP
fnp-3453	398	34	young	young	ADJ
fnp-3453	398	35	athletes	athlete	NOUN
fnp-3453	398	36	after	after	ADP
fnp-3453	398	37	impact	impact	NOUN
fnp-3453	398	38	head	head	NOUN
fnp-3453	398	39	injury	injury	NOUN
fnp-3453	398	40	and	and	CCONJ
fnp-3453	398	41	an	an	DET
fnp-3453	398	42	impact	impact	NOUN
fnp-3453	398	43	concussion	concussion	NOUN
fnp-3453	398	44	mouse	mouse	NOUN
fnp-3453	398	45	model	model	NOUN
fnp-3453	398	46	.	.	PUNCT
fnp-3453	399	1	brain	brain	NOUN
fnp-3453	399	2	141	141	NUM
fnp-3453	399	3	:	:	PUNCT
fnp-3453	399	4	422	422	NUM
fnp-3453	399	5	-	-	SYM
fnp-3453	399	6	458	458	NUM
fnp-3453	399	7	https://doi.org/10.1093/brain/awx350	https://doi.org/10.1093/brain/awx350	ADJ
fnp-3453	399	8	33	33	NUM
fnp-3453	399	9	.	.	PUNCT
fnp-3453	400	1	zhou	zhou	PROPN
fnp-3453	400	2	y	y	PROPN
fnp-3453	400	3	,	,	PUNCT
fnp-3453	400	4	zhou	zhou	PROPN
fnp-3453	400	5	b	b	PROPN
fnp-3453	400	6	,	,	PUNCT
fnp-3453	400	7	pache	pache	PROPN
fnp-3453	400	8	l	l	PROPN
fnp-3453	400	9	,	,	PUNCT
fnp-3453	400	10	chang	chang	PROPN
fnp-3453	400	11	m	m	PROPN
fnp-3453	400	12	,	,	PUNCT
fnp-3453	400	13	khodabakhshi	khodabakhshi	PROPN
fnp-3453	400	14	ah	ah	INTJ
fnp-3453	400	15	,	,	PUNCT
fnp-3453	400	16	tanaseichuk	tanaseichuk	NOUN
fnp-3453	400	17	o	o	X
fnp-3453	400	18	et	et	NOUN
fnp-3453	400	19	al	al	PROPN
fnp-3453	400	20	(	(	PUNCT
fnp-3453	400	21	2019	2019	NUM
fnp-3453	400	22	)	)	PUNCT
fnp-3453	400	23	metascape	metascape	NOUN
fnp-3453	400	24	provides	provide	VERB
fnp-3453	400	25	a	a	DET
fnp-3453	400	26	biologist	biologist	NOUN
fnp-3453	400	27	-	-	PUNCT
fnp-3453	400	28	oriented	orient	VERB
fnp-3453	400	29	resource	resource	NOUN
fnp-3453	400	30	for	for	ADP
fnp-3453	400	31	the	the	DET
fnp-3453	400	32	analysis	analysis	NOUN
fnp-3453	400	33	of	of	ADP
fnp-3453	400	34	systems	system	NOUN
fnp-3453	400	35	-	-	PUNCT
fnp-3453	400	36	level	level	NOUN
fnp-3453	400	37	datasets	dataset	NOUN
fnp-3453	400	38	.	.	PUNCT
fnp-3453	401	1	nat	nat	PROPN
fnp-3453	401	2	.	.	PUNCT
fnp-3453	402	1	commun	commun	PROPN
fnp-3453	402	2	10	10	NUM
fnp-3453	402	3	:	:	PUNCT
fnp-3453	402	4	1523	1523	NUM
fnp-3453	402	5	https://doi.org/10.1038/s41467-019-09234-6	https://doi.org/10.1038/s41467-019-09234-6	NUM
fnp-3453	402	6	copyright	copyright	NOUN
fnp-3453	402	7	:	:	PUNCT
fnp-3453	402	8	©	©	PROPN
fnp-3453	402	9	2021	2021	NUM
fnp-3453	402	10	the	the	DET
fnp-3453	402	11	author(s	author(s	NOUN
fnp-3453	402	12	)	)	PUNCT
fnp-3453	402	13	.	.	PUNCT
fnp-3453	403	1	this	this	PRON
fnp-3453	403	2	is	be	AUX
fnp-3453	403	3	an	an	DET
fnp-3453	403	4	open	open	ADJ
fnp-3453	403	5	access	access	NOUN
fnp-3453	403	6	article	article	NOUN
fnp-3453	403	7	distributed	distribute	VERB
fnp-3453	403	8	under	under	ADP
fnp-3453	403	9	the	the	DET
fnp-3453	403	10	terms	term	NOUN
fnp-3453	403	11	of	of	ADP
fnp-3453	403	12	the	the	DET
fnp-3453	403	13	creative	creative	ADJ
fnp-3453	403	14	commons	common	NOUN
fnp-3453	403	15	attribution	attribution	NOUN
fnp-3453	403	16	4.0	4.0	NUM
fnp-3453	403	17	international	international	ADJ
fnp-3453	403	18	license	license	NOUN
fnp-3453	403	19	(	(	PUNCT
fnp-3453	403	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3453	403	21	)	)	PUNCT
fnp-3453	403	22	,	,	PUNCT
fnp-3453	403	23	which	which	PRON
fnp-3453	403	24	permits	permit	VERB
fnp-3453	403	25	unrestricted	unrestricted	ADJ
fnp-3453	403	26	use	use	NOUN
fnp-3453	403	27	,	,	PUNCT
fnp-3453	403	28	distribution	distribution	NOUN
fnp-3453	403	29	,	,	PUNCT
fnp-3453	403	30	and	and	CCONJ
fnp-3453	403	31	reproduction	reproduction	NOUN
fnp-3453	403	32	in	in	ADP
fnp-3453	403	33	any	any	DET
fnp-3453	403	34	medium	medium	NOUN
fnp-3453	403	35	,	,	PUNCT
fnp-3453	403	36	provided	provide	VERB
fnp-3453	403	37	the	the	DET
fnp-3453	403	38	original	original	ADJ
fnp-3453	403	39	author	author	NOUN
fnp-3453	403	40	and	and	CCONJ
fnp-3453	403	41	source	source	NOUN
fnp-3453	403	42	are	be	AUX
fnp-3453	403	43	credited	credit	VERB
fnp-3453	403	44	,	,	PUNCT
fnp-3453	403	45	a	a	DET
fnp-3453	403	46	link	link	NOUN
fnp-3453	403	47	to	to	ADP
fnp-3453	403	48	the	the	DET
fnp-3453	403	49	creative	creative	ADJ
fnp-3453	403	50	commons	common	NOUN
fnp-3453	403	51	license	license	NOUN
fnp-3453	403	52	is	be	AUX
fnp-3453	403	53	provided	provide	VERB
fnp-3453	403	54	,	,	PUNCT
fnp-3453	403	55	and	and	CCONJ
fnp-3453	403	56	any	any	DET
fnp-3453	403	57	changes	change	NOUN
fnp-3453	403	58	are	be	AUX
fnp-3453	403	59	indicated	indicate	VERB
fnp-3453	403	60	.	.	PUNCT
fnp-3453	404	1	the	the	DET
fnp-3453	404	2	creative	creative	ADJ
fnp-3453	404	3	commons	common	NOUN
fnp-3453	404	4	public	public	ADJ
fnp-3453	404	5	domain	domain	NOUN
fnp-3453	404	6	dedication	dedication	NOUN
fnp-3453	404	7	waiver	waiver	NOUN
fnp-3453	404	8	(	(	PUNCT
fnp-3453	404	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3453	404	10	)	)	PUNCT
fnp-3453	404	11	applies	apply	VERB
fnp-3453	404	12	to	to	ADP
fnp-3453	404	13	the	the	DET
fnp-3453	404	14	data	datum	NOUN
fnp-3453	404	15	made	make	VERB
fnp-3453	404	16	available	available	ADJ
fnp-3453	404	17	in	in	ADP
fnp-3453	404	18	this	this	DET
fnp-3453	404	19	article	article	NOUN
fnp-3453	404	20	,	,	PUNCT
fnp-3453	404	21	unless	unless	SCONJ
fnp-3453	404	22	otherwise	otherwise	ADV
fnp-3453	404	23	stated	state	VERB
fnp-3453	404	24	.	.	PUNCT