id	sid	tid	token	lemma	pos
fnp-3528	1	1	strategies	strategy	NOUN
fnp-3528	1	2	to	to	PART
fnp-3528	1	3	gain	gain	VERB
fnp-3528	1	4	novel	novel	ADJ
fnp-3528	1	5	alzheimer	alzheimer	PROPN
fnp-3528	1	6	’s	’s	PART
fnp-3528	1	7	disease	disease	NOUN
fnp-3528	1	8	diagnostics	diagnostic	NOUN
fnp-3528	1	9	and	and	CCONJ
fnp-3528	1	10	therapeutics	therapeutic	NOUN
fnp-3528	1	11	using	use	VERB
fnp-3528	1	12	modulators	modulator	NOUN
fnp-3528	1	13	of	of	ADP
fnp-3528	1	14	abca	abca	NOUN
fnp-3528	1	15	transporters	transporter	NOUN
fnp-3528	1	16	feel	feel	VERB
fnp-3528	1	17	free	free	ADJ
fnp-3528	1	18	to	to	PART
fnp-3528	1	19	add	add	VERB
fnp-3528	1	20	comments	comment	NOUN
fnp-3528	1	21	by	by	ADP
fnp-3528	1	22	clicking	click	VERB
fnp-3528	1	23	these	these	DET
fnp-3528	1	24	icons	icon	NOUN
fnp-3528	1	25	on	on	ADP
fnp-3528	1	26	the	the	DET
fnp-3528	1	27	sidebar	sidebar	NOUN
fnp-3528	1	28	free	free	ADJ
fnp-3528	1	29	neuropathology	neuropathology	NOUN
fnp-3528	1	30	2:33	2:33	NUM
fnp-3528	1	31	(	(	PUNCT
fnp-3528	1	32	2021	2021	NUM
fnp-3528	1	33	)	)	PUNCT
fnp-3528	1	34	review	review	NOUN
fnp-3528	1	35	strategies	strategy	NOUN
fnp-3528	1	36	to	to	PART
fnp-3528	1	37	gain	gain	VERB
fnp-3528	1	38	novel	novel	ADJ
fnp-3528	1	39	alzheimer	alzheimer	PROPN
fnp-3528	1	40	’s	’s	PART
fnp-3528	1	41	disease	disease	NOUN
fnp-3528	1	42	diagnostics	diagnostic	NOUN
fnp-3528	1	43	and	and	CCONJ
fnp-3528	1	44	therapeutics	therapeutic	NOUN
fnp-3528	1	45	using	use	VERB
fnp-3528	1	46	modulators	modulator	NOUN
fnp-3528	1	47	of	of	ADP
fnp-3528	1	48	abca	abca	PROPN
fnp-3528	1	49	transporters	transporter	NOUN
fnp-3528	1	50	jens	jens	PROPN
fnp-3528	1	51	pahnke1,2,3	pahnke1,2,3	ADV
fnp-3528	1	52	,	,	PUNCT
fnp-3528	1	53	pablo	pablo	PROPN
fnp-3528	1	54	bascuñana1	bascuñana1	PROPN
fnp-3528	1	55	,	,	PUNCT
fnp-3528	1	56	mirjam	mirjam	PROPN
fnp-3528	1	57	brackhan1,2	brackhan1,2	PROPN
fnp-3528	1	58	,	,	PUNCT
fnp-3528	1	59	katja	katja	PROPN
fnp-3528	1	60	stefan1	stefan1	ADV
fnp-3528	1	61	,	,	PUNCT
fnp-3528	1	62	vigneshwaran	vigneshwaran	PROPN
fnp-3528	1	63	namasivayam4	namasivayam4	PROPN
fnp-3528	1	64	,	,	PUNCT
fnp-3528	1	65	radosveta	radosveta	ADJ
fnp-3528	1	66	koldamova5	koldamova5	PROPN
fnp-3528	1	67	,	,	PUNCT
fnp-3528	1	68	jingyun	jingyun	PROPN
fnp-3528	1	69	wu1	wu1	PROPN
fnp-3528	1	70	,	,	PUNCT
fnp-3528	1	71	luisa	luisa	PROPN
fnp-3528	1	72	möhle1	möhle1	PROPN
fnp-3528	1	73	,	,	PUNCT
fnp-3528	1	74	sven	sven	PROPN
fnp-3528	1	75	marcel	marcel	PROPN
fnp-3528	1	76	stefan1	stefan1	X
fnp-3528	1	77	1	1	NUM
fnp-3528	1	78	department	department	NOUN
fnp-3528	1	79	of	of	ADP
fnp-3528	1	80	pathology	pathology	PROPN
fnp-3528	1	81	,	,	PUNCT
fnp-3528	1	82	section	section	NOUN
fnp-3528	1	83	of	of	ADP
fnp-3528	1	84	neuropathology	neuropathology	NOUN
fnp-3528	1	85	,	,	PUNCT
fnp-3528	1	86	translational	translational	ADJ
fnp-3528	1	87	neurodegeneration	neurodegeneration	NOUN
fnp-3528	1	88	research	research	NOUN
fnp-3528	1	89	and	and	CCONJ
fnp-3528	1	90	neuropathology	neuropathology	NOUN
fnp-3528	1	91	lab	lab	NOUN
fnp-3528	1	92	,	,	PUNCT
fnp-3528	1	93	university	university	NOUN
fnp-3528	1	94	of	of	ADP
fnp-3528	1	95	oslo	oslo	PROPN
fnp-3528	1	96	and	and	CCONJ
fnp-3528	1	97	oslo	oslo	PROPN
fnp-3528	1	98	university	university	PROPN
fnp-3528	1	99	hospital	hospital	PROPN
fnp-3528	1	100	,	,	PUNCT
fnp-3528	1	101	oslo	oslo	PROPN
fnp-3528	1	102	,	,	PUNCT
fnp-3528	1	103	norway	norway	PROPN
fnp-3528	1	104	2	2	NUM
fnp-3528	1	105	lied	lie	VERB
fnp-3528	1	106	,	,	PUNCT
fnp-3528	1	107	university	university	NOUN
fnp-3528	1	108	of	of	ADP
fnp-3528	1	109	lübeck	lübeck	PROPN
fnp-3528	1	110	,	,	PUNCT
fnp-3528	1	111	lübeck	lübeck	PROPN
fnp-3528	1	112	,	,	PUNCT
fnp-3528	1	113	germany	germany	PROPN
fnp-3528	1	114	3	3	NUM
fnp-3528	1	115	department	department	PROPN
fnp-3528	1	116	of	of	ADP
fnp-3528	1	117	pharmacology	pharmacology	NOUN
fnp-3528	1	118	,	,	PUNCT
fnp-3528	1	119	faculty	faculty	NOUN
fnp-3528	1	120	of	of	ADP
fnp-3528	1	121	medicine	medicine	NOUN
fnp-3528	1	122	,	,	PUNCT
fnp-3528	1	123	university	university	PROPN
fnp-3528	1	124	of	of	ADP
fnp-3528	1	125	latvia	latvia	PROPN
fnp-3528	1	126	,	,	PUNCT
fnp-3528	1	127	rīga	rīga	PROPN
fnp-3528	1	128	,	,	PUNCT
fnp-3528	1	129	latvia	latvia	PROPN
fnp-3528	1	130	4	4	NUM
fnp-3528	1	131	department	department	NOUN
fnp-3528	1	132	of	of	ADP
fnp-3528	1	133	pharmaceutical	pharmaceutical	ADJ
fnp-3528	1	134	and	and	CCONJ
fnp-3528	1	135	cellbiological	cellbiological	ADJ
fnp-3528	1	136	chemistry	chemistry	NOUN
fnp-3528	1	137	,	,	PUNCT
fnp-3528	1	138	pharmaceutical	pharmaceutical	PROPN
fnp-3528	1	139	institute	institute	PROPN
fnp-3528	1	140	,	,	PUNCT
fnp-3528	1	141	university	university	PROPN
fnp-3528	1	142	of	of	ADP
fnp-3528	1	143	bonn	bonn	PROPN
fnp-3528	1	144	,	,	PUNCT
fnp-3528	1	145	bonn	bonn	PROPN
fnp-3528	1	146	,	,	PUNCT
fnp-3528	1	147	germany	germany	PROPN
fnp-3528	1	148	4	4	NUM
fnp-3528	1	149	department	department	PROPN
fnp-3528	1	150	of	of	ADP
fnp-3528	1	151	environmental	environmental	ADJ
fnp-3528	1	152	and	and	CCONJ
fnp-3528	1	153	occupational	occupational	ADJ
fnp-3528	1	154	health	health	NOUN
fnp-3528	1	155	,	,	PUNCT
fnp-3528	1	156	school	school	NOUN
fnp-3528	1	157	of	of	ADP
fnp-3528	1	158	public	public	ADJ
fnp-3528	1	159	health	health	NOUN
fnp-3528	1	160	,	,	PUNCT
fnp-3528	1	161	university	university	PROPN
fnp-3528	1	162	of	of	ADP
fnp-3528	1	163	pittsburgh	pittsburgh	PROPN
fnp-3528	1	164	,	,	PUNCT
fnp-3528	1	165	pittsburgh	pittsburgh	PROPN
fnp-3528	1	166	,	,	PUNCT
fnp-3528	1	167	pa	pa	PROPN
fnp-3528	1	168	,	,	PUNCT
fnp-3528	1	169	united	united	PROPN
fnp-3528	1	170	states	states	PROPN
fnp-3528	1	171	of	of	ADP
fnp-3528	1	172	america	america	PROPN
fnp-3528	1	173	corresponding	corresponding	PROPN
fnp-3528	1	174	author	author	NOUN
fnp-3528	1	175	:	:	PUNCT
fnp-3528	1	176	sven	sven	PROPN
fnp-3528	1	177	marcel	marcel	PROPN
fnp-3528	1	178	stefan	stefan	PROPN
fnp-3528	1	179	·	·	PUNCT
fnp-3528	1	180	department	department	PROPN
fnp-3528	1	181	of	of	ADP
fnp-3528	1	182	pathology	pathology	PROPN
fnp-3528	1	183	·	·	PUNCT
fnp-3528	1	184	section	section	NOUN
fnp-3528	1	185	of	of	ADP
fnp-3528	1	186	neuropathology	neuropathology	NOUN
fnp-3528	1	187	·	·	PUNCT
fnp-3528	1	188	translational	translational	ADJ
fnp-3528	1	189	neurodegeneration	neurodegeneration	NOUN
fnp-3528	1	190	research	research	NOUN
fnp-3528	1	191	and	and	CCONJ
fnp-3528	1	192	neuropathology	neuropathology	NOUN
fnp-3528	1	193	lab	lab	NOUN
fnp-3528	1	194	·	·	PUNCT
fnp-3528	1	195	www.pahnkelab.eu	www.pahnkelab.eu	X
fnp-3528	1	196	·	·	PUNCT
fnp-3528	1	197	university	university	PROPN
fnp-3528	1	198	of	of	ADP
fnp-3528	1	199	oslo	oslo	PROPN
fnp-3528	1	200	and	and	CCONJ
fnp-3528	1	201	oslo	oslo	PROPN
fnp-3528	1	202	university	university	PROPN
fnp-3528	1	203	hospital	hospital	PROPN
fnp-3528	1	204	·	·	PUNCT
fnp-3528	1	205	sognsvannsveien	sognsvannsveien	NOUN
fnp-3528	1	206	20	20	NUM
fnp-3528	1	207	·	·	SYM
fnp-3528	1	208	0372	0372	NUM
fnp-3528	1	209	oslo	oslo	PROPN
fnp-3528	1	210	·	·	PUNCT
fnp-3528	1	211	norway	norway	PROPN
fnp-3528	1	212	s.m.stefan@medisin.uio.no	s.m.stefan@medisin.uio.no	VERB
fnp-3528	1	213	submitted	submit	VERB
fnp-3528	1	214	:	:	PUNCT
fnp-3528	1	215	07	07	NUM
fnp-3528	1	216	september	september	PROPN
fnp-3528	1	217	2021	2021	NUM
fnp-3528	1	218	accepted	accept	VERB
fnp-3528	1	219	:	:	PUNCT
fnp-3528	1	220	12	12	NUM
fnp-3528	1	221	november	november	PROPN
fnp-3528	1	222	2021	2021	NUM
fnp-3528	1	223	copyedited	copyedit	VERB
fnp-3528	1	224	by	by	ADP
fnp-3528	1	225	:	:	PUNCT
fnp-3528	1	226	biswarathan	biswarathan	PROPN
fnp-3528	1	227	ramani	ramani	PROPN
fnp-3528	2	1	published	publish	VERB
fnp-3528	2	2	:	:	PUNCT
fnp-3528	3	1	13	13	NUM
fnp-3528	3	2	december	december	PROPN
fnp-3528	3	3	2021	2021	NUM
fnp-3528	3	4	https://doi.org/10.17879/freeneuropathology-2021-3528	https://doi.org/10.17879/freeneuropathology-2021-3528	NOUN
fnp-3528	3	5	keywords	keyword	NOUN
fnp-3528	3	6	:	:	PUNCT
fnp-3528	3	7	abc	abc	PROPN
fnp-3528	3	8	transporter	transporter	NOUN
fnp-3528	3	9	,	,	PUNCT
fnp-3528	3	10	abcb1	abcb1	NOUN
fnp-3528	3	11	(	(	PUNCT
fnp-3528	3	12	p	p	NOUN
fnp-3528	3	13	-	-	PUNCT
fnp-3528	3	14	gp	gp	NOUN
fnp-3528	3	15	)	)	PUNCT
fnp-3528	3	16	,	,	PUNCT
fnp-3528	3	17	abcc1	abcc1	PROPN
fnp-3528	3	18	(	(	PUNCT
fnp-3528	3	19	mrp1	mrp1	PROPN
fnp-3528	3	20	)	)	PUNCT
fnp-3528	3	21	,	,	PUNCT
fnp-3528	3	22	abcg2	abcg2	X
fnp-3528	3	23	(	(	PUNCT
fnp-3528	3	24	bcrp	bcrp	PROPN
fnp-3528	3	25	)	)	PUNCT
fnp-3528	3	26	,	,	PUNCT
fnp-3528	3	27	abca1	abca1	PROPN
fnp-3528	3	28	(	(	PUNCT
fnp-3528	3	29	abc1	abc1	PROPN
fnp-3528	3	30	)	)	PUNCT
fnp-3528	3	31	,	,	PUNCT
fnp-3528	3	32	abca2	abca2	PROPN
fnp-3528	3	33	,	,	PUNCT
fnp-3528	3	34	abca5	abca5	PROPN
fnp-3528	3	35	,	,	PUNCT
fnp-3528	3	36	abca7	abca7	PROPN
fnp-3528	3	37	,	,	PUNCT
fnp-3528	3	38	multitarget	multitarget	PROPN
fnp-3528	3	39	inhibitor	inhibitor	NOUN
fnp-3528	3	40	(	(	PUNCT
fnp-3528	3	41	panabc	panabc	PROPN
fnp-3528	3	42	)	)	PUNCT
fnp-3528	3	43	,	,	PUNCT
fnp-3528	3	44	broad	broad	ADJ
fnp-3528	3	45	-	-	PUNCT
fnp-3528	3	46	spectrum	spectrum	NOUN
fnp-3528	3	47	modulator	modulator	NOUN
fnp-3528	3	48	,	,	PUNCT
fnp-3528	3	49	alzheimer	alzheimer	PROPN
fnp-3528	3	50	’s	’s	PART
fnp-3528	3	51	disease	disease	NOUN
fnp-3528	3	52	,	,	PUNCT
fnp-3528	3	53	amyloid	amyloid	NOUN
fnp-3528	3	54	-	-	PUNCT
fnp-3528	3	55	beta	beta	NOUN
fnp-3528	3	56	(	(	PUNCT
fnp-3528	3	57	aβ	aβ	PROPN
fnp-3528	3	58	/	/	SYM
fnp-3528	3	59	abeta	abeta	PROPN
fnp-3528	3	60	)	)	PUNCT
fnp-3528	3	61	,	,	PUNCT
fnp-3528	3	62	inhibition	inhibition	NOUN
fnp-3528	3	63	,	,	PUNCT
fnp-3528	3	64	activation	activation	NOUN
fnp-3528	3	65	,	,	PUNCT
fnp-3528	3	66	induction	induction	NOUN
fnp-3528	3	67	,	,	PUNCT
fnp-3528	3	68	downregulation	downregulation	NOUN
fnp-3528	3	69	,	,	PUNCT
fnp-3528	3	70	pet	pet	ADJ
fnp-3528	3	71	tracer	tracer	NOUN
fnp-3528	3	72	(	(	PUNCT
fnp-3528	3	73	petabc	petabc	PROPN
fnp-3528	3	74	)	)	PUNCT
fnp-3528	3	75	,	,	PUNCT
fnp-3528	3	76	pattern	pattern	NOUN
fnp-3528	3	77	analysis	analysis	NOUN
fnp-3528	3	78	,	,	PUNCT
fnp-3528	3	79	polypharmacology	polypharmacology	NOUN
fnp-3528	3	80	,	,	PUNCT
fnp-3528	3	81	rational	rational	ADJ
fnp-3528	3	82	drug	drug	NOUN
fnp-3528	3	83	design	design	NOUN
fnp-3528	3	84	and	and	CCONJ
fnp-3528	3	85	development	development	NOUN
fnp-3528	3	86	abstract	abstract	ADJ
fnp-3528	3	87	adenosine	adenosine	NOUN
fnp-3528	3	88	-	-	PUNCT
fnp-3528	3	89	triphosphate-(atp)-binding	triphosphate-(atp)-binde	VERB
fnp-3528	3	90	cassette	cassette	NOUN
fnp-3528	3	91	(	(	PUNCT
fnp-3528	3	92	abc	abc	PROPN
fnp-3528	3	93	)	)	PUNCT
fnp-3528	3	94	transport	transport	NOUN
fnp-3528	3	95	proteins	protein	NOUN
fnp-3528	3	96	are	be	AUX
fnp-3528	3	97	ubiquitously	ubiquitously	ADV
fnp-3528	3	98	present	present	ADJ
fnp-3528	3	99	membrane	membrane	NOUN
fnp-3528	3	100	-	-	PUNCT
fnp-3528	3	101	bound	bind	VERB
fnp-3528	3	102	efflux	efflux	NOUN
fnp-3528	3	103	pumps	pump	NOUN
fnp-3528	3	104	that	that	PRON
fnp-3528	3	105	distribute	distribute	VERB
fnp-3528	3	106	endoand	endoand	PROPN
fnp-3528	3	107	xenobiotics	xenobiotics	PROPN
fnp-3528	3	108	across	across	ADP
fnp-3528	3	109	intraand	intraand	CCONJ
fnp-3528	3	110	intercellular	intercellular	ADJ
fnp-3528	3	111	barriers	barrier	NOUN
fnp-3528	3	112	.	.	PUNCT
fnp-3528	4	1	discovered	discover	VERB
fnp-3528	4	2	over	over	ADP
fnp-3528	4	3	40	40	NUM
fnp-3528	4	4	years	year	NOUN
fnp-3528	4	5	ago	ago	ADV
fnp-3528	4	6	,	,	PUNCT
fnp-3528	4	7	abc	abc	PROPN
fnp-3528	4	8	transporters	transporter	NOUN
fnp-3528	4	9	have	have	AUX
fnp-3528	4	10	been	be	AUX
fnp-3528	4	11	identified	identify	VERB
fnp-3528	4	12	as	as	ADP
fnp-3528	4	13	key	key	ADJ
fnp-3528	4	14	players	player	NOUN
fnp-3528	4	15	in	in	ADP
fnp-3528	4	16	various	various	ADJ
fnp-3528	4	17	human	human	ADJ
fnp-3528	4	18	diseases	disease	NOUN
fnp-3528	4	19	,	,	PUNCT
fnp-3528	4	20	such	such	ADJ
fnp-3528	4	21	as	as	ADP
fnp-3528	4	22	multidrug	multidrug	NOUN
fnp-3528	4	23	-	-	PUNCT
fnp-3528	4	24	resistant	resistant	ADJ
fnp-3528	4	25	cancer	cancer	NOUN
fnp-3528	4	26	and	and	CCONJ
fnp-3528	4	27	atherosclerosis	atherosclerosis	NOUN
fnp-3528	4	28	,	,	PUNCT
fnp-3528	4	29	but	but	CCONJ
fnp-3528	4	30	also	also	ADV
fnp-3528	4	31	neurodegenerative	neurodegenerative	ADJ
fnp-3528	4	32	diseases	disease	NOUN
fnp-3528	4	33	,	,	PUNCT
fnp-3528	4	34	such	such	ADJ
fnp-3528	4	35	as	as	ADP
fnp-3528	4	36	alzheimer	alzheimer	PROPN
fnp-3528	4	37	’s	’s	PART
fnp-3528	4	38	disease	disease	NOUN
fnp-3528	4	39	(	(	PUNCT
fnp-3528	4	40	ad	ad	NOUN
fnp-3528	4	41	)	)	PUNCT
fnp-3528	4	42	.	.	PUNCT
fnp-3528	5	1	most	most	ADV
fnp-3528	5	2	prominent	prominent	ADJ
fnp-3528	5	3	and	and	CCONJ
fnp-3528	5	4	well	well	ADV
fnp-3528	5	5	-	-	PUNCT
fnp-3528	5	6	studied	study	VERB
fnp-3528	5	7	are	be	AUX
fnp-3528	5	8	abcb1	abcb1	NOUN
fnp-3528	5	9	,	,	PUNCT
fnp-3528	5	10	abcc1	abcc1	PROPN
fnp-3528	5	11	,	,	PUNCT
fnp-3528	5	12	and	and	CCONJ
fnp-3528	5	13	abcg2	abcg2	NOUN
fnp-3528	5	14	,	,	PUNCT
fnp-3528	5	15	not	not	PART
fnp-3528	5	16	only	only	ADV
fnp-3528	5	17	due	due	ADJ
fnp-3528	5	18	to	to	ADP
fnp-3528	5	19	their	their	PRON
fnp-3528	5	20	contribution	contribution	NOUN
fnp-3528	5	21	to	to	ADP
fnp-3528	5	22	the	the	DET
fnp-3528	5	23	multidrug	multidrug	NOUN
fnp-3528	5	24	resistance	resistance	NOUN
fnp-3528	5	25	(	(	PUNCT
fnp-3528	5	26	mdr	mdr	NOUN
fnp-3528	5	27	)	)	PUNCT
fnp-3528	5	28	phenotype	phenotype	NOUN
fnp-3528	5	29	in	in	ADP
fnp-3528	5	30	cancer	cancer	NOUN
fnp-3528	5	31	,	,	PUNCT
fnp-3528	5	32	but	but	CCONJ
fnp-3528	5	33	also	also	ADV
fnp-3528	5	34	due	due	ADP
fnp-3528	5	35	to	to	ADP
fnp-3528	5	36	their	their	PRON
fnp-3528	5	37	contribution	contribution	NOUN
fnp-3528	5	38	to	to	ADP
fnp-3528	5	39	ad	ad	NOUN
fnp-3528	5	40	.	.	PUNCT
fnp-3528	6	1	however	however	ADV
fnp-3528	6	2	,	,	PUNCT
fnp-3528	6	3	our	our	PRON
fnp-3528	6	4	understanding	understanding	NOUN
fnp-3528	6	5	of	of	ADP
fnp-3528	6	6	other	other	ADJ
fnp-3528	6	7	abc	abc	PROPN
fnp-3528	6	8	transporters	transporter	NOUN
fnp-3528	6	9	is	be	AUX
fnp-3528	6	10	limited	limit	VERB
fnp-3528	6	11	,	,	PUNCT
fnp-3528	6	12	and	and	CCONJ
fnp-3528	6	13	most	most	ADJ
fnp-3528	6	14	of	of	ADP
fnp-3528	6	15	the	the	DET
fnp-3528	6	16	49	49	NUM
fnp-3528	6	17	human	human	ADJ
fnp-3528	6	18	abc	abc	PROPN
fnp-3528	6	19	transporters	transporter	NOUN
fnp-3528	6	20	have	have	AUX
fnp-3528	6	21	been	be	AUX
fnp-3528	6	22	largely	largely	ADV
fnp-3528	6	23	neglected	neglect	VERB
fnp-3528	6	24	as	as	ADP
fnp-3528	6	25	potential	potential	ADJ
fnp-3528	6	26	targets	target	NOUN
fnp-3528	6	27	for	for	ADP
fnp-3528	6	28	novel	novel	ADJ
fnp-3528	6	29	small	small	ADJ
fnp-3528	6	30	-	-	PUNCT
fnp-3528	6	31	molecule	molecule	NOUN
fnp-3528	6	32	drugs	drug	NOUN
fnp-3528	6	33	.	.	PUNCT
fnp-3528	7	1	this	this	PRON
fnp-3528	7	2	is	be	AUX
fnp-3528	7	3	especially	especially	ADV
fnp-3528	7	4	true	true	ADJ
fnp-3528	7	5	for	for	ADP
fnp-3528	7	6	the	the	DET
fnp-3528	7	7	abca	abca	NOUN
fnp-3528	7	8	subfamily	subfamily	ADV
fnp-3528	7	9	,	,	PUNCT
fnp-3528	7	10	which	which	PRON
fnp-3528	7	11	contains	contain	VERB
fnp-3528	7	12	several	several	ADJ
fnp-3528	7	13	members	member	NOUN
fnp-3528	7	14	known	know	VERB
fnp-3528	7	15	to	to	PART
fnp-3528	7	16	play	play	VERB
fnp-3528	7	17	a	a	DET
fnp-3528	7	18	role	role	NOUN
fnp-3528	7	19	in	in	ADP
fnp-3528	7	20	ad	ad	NOUN
fnp-3528	7	21	initiation	initiation	NOUN
fnp-3528	7	22	and	and	CCONJ
fnp-3528	7	23	progression	progression	NOUN
fnp-3528	7	24	.	.	PUNCT
fnp-3528	8	1	this	this	DET
fnp-3528	8	2	review	review	NOUN
fnp-3528	8	3	provides	provide	VERB
fnp-3528	8	4	up	up	ADP
fnp-3528	8	5	-	-	PUNCT
fnp-3528	8	6	to	to	ADP
fnp-3528	8	7	-	-	PUNCT
fnp-3528	8	8	date	date	NOUN
fnp-3528	8	9	information	information	NOUN
fnp-3528	8	10	on	on	ADP
fnp-3528	8	11	the	the	DET
fnp-3528	8	12	proposed	propose	VERB
fnp-3528	8	13	functional	functional	ADJ
fnp-3528	8	14	background	background	NOUN
fnp-3528	8	15	and	and	CCONJ
fnp-3528	8	16	pathological	pathological	ADJ
fnp-3528	8	17	role	role	NOUN
fnp-3528	8	18	of	of	ADP
fnp-3528	8	19	abca	abca	NOUN
fnp-3528	8	20	transporters	transporter	NOUN
fnp-3528	8	21	in	in	ADP
fnp-3528	8	22	ad	ad	NOUN
fnp-3528	8	23	.	.	PUNCT
fnp-3528	9	1	we	we	PRON
fnp-3528	9	2	also	also	ADV
fnp-3528	9	3	provide	provide	VERB
fnp-3528	9	4	an	an	DET
fnp-3528	9	5	overview	overview	NOUN
fnp-3528	9	6	of	of	ADP
fnp-3528	9	7	small	small	ADJ
fnp-3528	9	8	-	-	PUNCT
fnp-3528	9	9	molecules	molecule	NOUN
fnp-3528	9	10	shown	show	VERB
fnp-3528	9	11	to	to	PART
fnp-3528	9	12	interact	interact	VERB
fnp-3528	9	13	with	with	ADP
fnp-3528	9	14	abca	abca	PROPN
fnp-3528	9	15	transporters	transporter	NOUN
fnp-3528	9	16	as	as	ADV
fnp-3528	9	17	well	well	ADV
fnp-3528	9	18	as	as	ADP
fnp-3528	9	19	potential	potential	ADJ
fnp-3528	9	20	in	in	ADP
fnp-3528	9	21	silico	silico	NOUN
fnp-3528	9	22	,	,	PUNCT
fnp-3528	9	23	in	in	ADP
fnp-3528	9	24	vitro	vitro	NOUN
fnp-3528	9	25	,	,	PUNCT
fnp-3528	9	26	and	and	CCONJ
fnp-3528	9	27	in	in	ADP
fnp-3528	9	28	vivo	vivo	ADJ
fnp-3528	9	29	methodologies	methodology	NOUN
fnp-3528	9	30	to	to	PART
fnp-3528	9	31	gain	gain	VERB
fnp-3528	9	32	novel	novel	ADJ
fnp-3528	9	33	templates	template	NOUN
fnp-3528	9	34	for	for	ADP
fnp-3528	9	35	the	the	DET
fnp-3528	9	36	development	development	NOUN
fnp-3528	9	37	of	of	ADP
fnp-3528	9	38	innovative	innovative	ADJ
fnp-3528	9	39	abc	abc	PROPN
fnp-3528	9	40	transporter	transporter	NOUN
fnp-3528	9	41	-	-	PUNCT
fnp-3528	9	42	targeting	target	VERB
fnp-3528	9	43	diagnostics	diagnostic	NOUN
fnp-3528	9	44	and	and	CCONJ
fnp-3528	9	45	therapeutics	therapeutic	NOUN
fnp-3528	9	46	.	.	PUNCT
fnp-3528	10	1	introduction	introduction	NOUN
fnp-3528	10	2	from	from	ADP
fnp-3528	10	3	mdr	mdr	PROPN
fnp-3528	10	4	to	to	ADP
fnp-3528	10	5	neurodegeneration	neurodegeneration	NOUN
fnp-3528	10	6	:	:	PUNCT
fnp-3528	10	7	abc	abc	PROPN
fnp-3528	10	8	transporters	transporter	NOUN
fnp-3528	10	9	in	in	ADP
fnp-3528	10	10	human	human	ADJ
fnp-3528	10	11	disease	disease	NOUN
fnp-3528	10	12	abc	abc	PROPN
fnp-3528	10	13	transporters	transporter	NOUN
fnp-3528	10	14	,	,	PUNCT
fnp-3528	10	15	aβ	aβ	DET
fnp-3528	10	16	proteins	protein	NOUN
fnp-3528	10	17	,	,	PUNCT
fnp-3528	10	18	and	and	CCONJ
fnp-3528	10	19	ad	ad	NOUN
fnp-3528	10	20	part	part	NOUN
fnp-3528	11	1	i	i	NOUN
fnp-3528	11	2	:	:	PUNCT
fnp-3528	11	3	status	status	NOUN
fnp-3528	11	4	quo	quo	PROPN
fnp-3528	11	5	abca	abca	NOUN
fnp-3528	11	6	transporters	transporter	NOUN
fnp-3528	11	7	:	:	PUNCT
fnp-3528	11	8	physiological	physiological	ADJ
fnp-3528	11	9	function	function	NOUN
fnp-3528	11	10	and	and	CCONJ
fnp-3528	11	11	implications	implication	NOUN
fnp-3528	11	12	for	for	ADP
fnp-3528	11	13	ad	ad	NOUN
fnp-3528	11	14	abca1	abca1	NOUN
fnp-3528	11	15	abca2	abca2	NOUN
fnp-3528	11	16	abca3	abca3	PROPN
fnp-3528	11	17	abca4	abca4	PROPN
fnp-3528	11	18	abca5	abca5	PROPN
fnp-3528	12	1	abca6	abca6	PROPN
fnp-3528	12	2	abca7	abca7	PROPN
fnp-3528	12	3	abca8	abca8	PROPN
fnp-3528	12	4	–	–	PUNCT
fnp-3528	12	5	abca10	abca10	X
fnp-3528	12	6	abca12	abca12	NOUN
fnp-3528	12	7	abca13	abca13	NOUN
fnp-3528	12	8	modulators	modulator	NOUN
fnp-3528	12	9	of	of	ADP
fnp-3528	12	10	abca	abca	NOUN
fnp-3528	12	11	transporter	transporter	NOUN
fnp-3528	12	12	function	function	NOUN
fnp-3528	12	13	,	,	PUNCT
fnp-3528	12	14	trafficking	trafficking	NOUN
fnp-3528	12	15	,	,	PUNCT
fnp-3528	12	16	and	and	CCONJ
fnp-3528	12	17	regulation	regulation	VERB
fnp-3528	12	18	small	small	ADJ
fnp-3528	12	19	-	-	PUNCT
fnp-3528	12	20	molecule	molecule	NOUN
fnp-3528	12	21	interactors	interactor	NOUN
fnp-3528	12	22	of	of	ADP
fnp-3528	12	23	abca	abca	PROPN
fnp-3528	12	24	transporters	transporter	NOUN
fnp-3528	12	25	small	small	ADJ
fnp-3528	12	26	-	-	PUNCT
fnp-3528	12	27	molecule	molecule	NOUN
fnp-3528	12	28	regulators	regulator	NOUN
fnp-3528	12	29	of	of	ADP
fnp-3528	12	30	abca	abca	PROPN
fnp-3528	12	31	transporters	transporter	NOUN
fnp-3528	12	32	part	part	NOUN
fnp-3528	12	33	ii	ii	NOUN
fnp-3528	12	34	:	:	PUNCT
fnp-3528	12	35	pipeline	pipeline	NOUN
fnp-3528	12	36	development	development	NOUN
fnp-3528	12	37	to	to	PART
fnp-3528	12	38	gain	gain	VERB
fnp-3528	12	39	novel	novel	ADJ
fnp-3528	12	40	diagnostics	diagnostic	NOUN
fnp-3528	12	41	and	and	CCONJ
fnp-3528	12	42	therapeutics	therapeutic	NOUN
fnp-3528	12	43	in	in	ADP
fnp-3528	12	44	silico	silico	NOUN
fnp-3528	12	45	methodologies	methodology	NOUN
fnp-3528	12	46	to	to	PART
fnp-3528	12	47	predict	predict	VERB
fnp-3528	12	48	novel	novel	ADJ
fnp-3528	12	49	lead	lead	NOUN
fnp-3528	12	50	structures	structure	NOUN
fnp-3528	12	51	structure	structure	NOUN
fnp-3528	12	52	-	-	PUNCT
fnp-3528	12	53	based	base	VERB
fnp-3528	12	54	drug	drug	NOUN
fnp-3528	12	55	design	design	NOUN
fnp-3528	12	56	ligand	ligand	NOUN
fnp-3528	12	57	-	-	PUNCT
fnp-3528	12	58	based	base	VERB
fnp-3528	12	59	drug	drug	NOUN
fnp-3528	12	60	design	design	NOUN
fnp-3528	12	61	in	in	ADP
fnp-3528	12	62	vitro	vitro	X
fnp-3528	12	63	methodologies	methodology	NOUN
fnp-3528	12	64	to	to	PART
fnp-3528	12	65	assess	assess	VERB
fnp-3528	12	66	novel	novel	ADJ
fnp-3528	12	67	lead	lead	NOUN
fnp-3528	12	68	structures	structure	NOUN
fnp-3528	12	69	host	host	NOUN
fnp-3528	12	70	system	system	NOUN
fnp-3528	12	71	of	of	ADP
fnp-3528	12	72	abca	abca	PROPN
fnp-3528	12	73	transporters	transporter	NOUN
fnp-3528	12	74	functional	functional	ADJ
fnp-3528	12	75	assessment	assessment	NOUN
fnp-3528	12	76	of	of	ADP
fnp-3528	12	77	abca	abca	NOUN
fnp-3528	12	78	transporters	transporter	NOUN
fnp-3528	12	79	in	in	ADP
fnp-3528	12	80	vivo	vivo	ADJ
fnp-3528	12	81	assessment	assessment	NOUN
fnp-3528	12	82	of	of	ADP
fnp-3528	12	83	clinical	clinical	ADJ
fnp-3528	12	84	candidates	candidate	NOUN
fnp-3528	12	85	knock	knock	VERB
fnp-3528	12	86	-	-	PUNCT
fnp-3528	12	87	out	out	ADP
fnp-3528	12	88	mouse	mouse	NOUN
fnp-3528	12	89	models	model	NOUN
fnp-3528	12	90	rnai	rnai	NOUN
fnp-3528	12	91	models	model	NOUN
fnp-3528	12	92	overexpression	overexpression	NOUN
fnp-3528	12	93	models	model	NOUN
fnp-3528	12	94	humanized	humanize	VERB
fnp-3528	12	95	abc	abc	PROPN
fnp-3528	12	96	transporter	transporter	NOUN
fnp-3528	12	97	mouse	mouse	NOUN
fnp-3528	12	98	models	model	NOUN
fnp-3528	12	99	disease	disease	NOUN
fnp-3528	12	100	models	model	NOUN
fnp-3528	12	101	imaging	image	VERB
fnp-3528	12	102	techniques	technique	NOUN
fnp-3528	12	103	concluding	conclude	VERB
fnp-3528	12	104	remarks	remark	VERB
fnp-3528	12	105	:	:	PUNCT
fnp-3528	12	106	where	where	SCONJ
fnp-3528	12	107	do	do	AUX
fnp-3528	12	108	we	we	PRON
fnp-3528	12	109	go	go	VERB
fnp-3528	12	110	from	from	ADP
fnp-3528	12	111	here	here	ADV
fnp-3528	12	112	?	?	PUNCT
fnp-3528	13	1	appendix	appendix	VERB
fnp-3528	13	2	abbreviations	abbreviation	NOUN
fnp-3528	13	3	5	5	NUM
fnp-3528	13	4	-	-	PUNCT
fnp-3528	13	5	fu	fu	ADJ
fnp-3528	13	6	5	5	NUM
fnp-3528	13	7	-	-	PUNCT
fnp-3528	13	8	fluorouracil	fluorouracil	NOUN
fnp-3528	13	9	,	,	PUNCT
fnp-3528	13	10	aβ	aβ	DET
fnp-3528	13	11	amyloid	amyloid	NOUN
fnp-3528	13	12	-	-	PUNCT
fnp-3528	13	13	β	β	NOUN
fnp-3528	13	14	,	,	PUNCT
fnp-3528	13	15	abca	abca	PROPN
fnp-3528	13	16	atp	atp	PROPN
fnp-3528	13	17	-	-	PUNCT
fnp-3528	13	18	binding	bind	VERB
fnp-3528	13	19	cassette	cassette	NOUN
fnp-3528	13	20	transporter	transporter	NOUN
fnp-3528	13	21	subfamily	subfamily	ADV
fnp-3528	13	22	a	a	PRON
fnp-3528	13	23	,	,	PUNCT
fnp-3528	13	24	acat	acat	ADJ
fnp-3528	13	25	acyl	acyl	ADJ
fnp-3528	13	26	coenzyme	coenzyme	PROPN
fnp-3528	13	27	a	a	DET
fnp-3528	13	28	cholesteryl	cholesteryl	PROPN
fnp-3528	13	29	acyl	acyl	NOUN
fnp-3528	13	30	transferase	transferase	NOUN
fnp-3528	13	31	,	,	PUNCT
fnp-3528	13	32	ad	ad	NOUN
fnp-3528	13	33	alzheimer	alzheimer	PROPN
fnp-3528	13	34	’s	’s	PART
fnp-3528	13	35	disease	disease	NOUN
fnp-3528	13	36	,	,	PUNCT
fnp-3528	13	37	adma	adma	PROPN
fnp-3528	13	38	asymmetric	asymmetric	PROPN
fnp-3528	13	39	dimethylarginine	dimethylarginine	PROPN
fnp-3528	13	40	,	,	PUNCT
fnp-3528	13	41	adp	adp	PROPN
fnp-3528	13	42	adenosine	adenosine	NOUN
fnp-3528	13	43	-	-	PUNCT
fnp-3528	13	44	diphosphate	diphosphate	NOUN
fnp-3528	13	45	,	,	PUNCT
fnp-3528	13	46	als	als	VERB
fnp-3528	13	47	amyotrophic	amyotrophic	ADJ
fnp-3528	13	48	lateral	lateral	ADJ
fnp-3528	13	49	sclerosis	sclerosis	NOUN
fnp-3528	13	50	,	,	PUNCT
fnp-3528	13	51	ampk	ampk	NOUN
fnp-3528	13	52	camp	camp	NOUN
fnp-3528	13	53	-	-	PUNCT
fnp-3528	13	54	activated	activate	VERB
fnp-3528	13	55	protein	protein	NOUN
fnp-3528	13	56	kinase	kinase	NOUN
fnp-3528	13	57	,	,	PUNCT
fnp-3528	13	58	apoa1	apoa1	PROPN
fnp-3528	13	59	/	/	SYM
fnp-3528	13	60	e3	e3	NOUN
fnp-3528	13	61	/	/	SYM
fnp-3528	13	62	e4	e4	PROPN
fnp-3528	13	63	apolipoprotein	apolipoprotein	ADJ
fnp-3528	13	64	a1	a1	PROPN
fnp-3528	13	65	/	/	SYM
fnp-3528	13	66	e3	e3	NOUN
fnp-3528	13	67	/	/	SYM
fnp-3528	13	68	e4	e4	PROPN
fnp-3528	13	69	,	,	PUNCT
fnp-3528	13	70	app	app	NOUN
fnp-3528	13	71	amyloid	amyloid	NOUN
fnp-3528	13	72	precursor	precursor	NOUN
fnp-3528	13	73	protein	protein	NOUN
fnp-3528	13	74	,	,	PUNCT
fnp-3528	13	75	atp	atp	NOUN
fnp-3528	13	76	adenosine	adenosine	NOUN
fnp-3528	13	77	-	-	PUNCT
fnp-3528	13	78	triphosphate	triphosphate	NOUN
fnp-3528	13	79	,	,	PUNCT
fnp-3528	13	80	bbb	bbb	NOUN
fnp-3528	13	81	blood	blood	NOUN
fnp-3528	13	82	-	-	PUNCT
fnp-3528	13	83	brain	brain	NOUN
fnp-3528	13	84	barrier	barrier	NOUN
fnp-3528	13	85	,	,	PUNCT
fnp-3528	13	86	bcsfb	bcsfb	VERB
fnp-3528	13	87	blood	blood	NOUN
fnp-3528	13	88	-	-	PUNCT
fnp-3528	13	89	cerebrospinal	cerebrospinal	ADJ
fnp-3528	13	90	fluid	fluid	NOUN
fnp-3528	13	91	barrier	barrier	NOUN
fnp-3528	13	92	,	,	PUNCT
fnp-3528	13	93	bhk	bhk	PROPN
fnp-3528	13	94	baby	baby	PROPN
fnp-3528	13	95	hamster	hamster	PROPN
fnp-3528	13	96	kidney	kidney	PROPN
fnp-3528	13	97	,	,	PUNCT
fnp-3528	13	98	big1	big1	NOUN
fnp-3528	13	99	brefeldin	brefeldin	VERB
fnp-3528	13	100	1	1	NUM
fnp-3528	13	101	-	-	PUNCT
fnp-3528	13	102	inhibited	inhibit	VERB
fnp-3528	13	103	guanine	guanine	NOUN
fnp-3528	13	104	nucleotide	nucleotide	PROPN
fnp-3528	13	105	exchange	exchange	PROPN
fnp-3528	13	106	protein	protein	NOUN
fnp-3528	13	107	,	,	PUNCT
fnp-3528	13	108	bodipy	bodipy	NOUN
fnp-3528	13	109	4,4	4,4	NUM
fnp-3528	13	110	-	-	PUNCT
fnp-3528	13	111	difluoro-4	difluoro-4	NOUN
fnp-3528	13	112	-	-	PUNCT
fnp-3528	13	113	bora-3a,4a	bora-3a,4a	VERB
fnp-3528	13	114	-	-	PUNCT
fnp-3528	13	115	diaza	diaza	NOUN
fnp-3528	13	116	-	-	PUNCT
fnp-3528	13	117	s	s	NOUN
fnp-3528	13	118	-	-	PUNCT
fnp-3528	13	119	indacene	indacene	NOUN
fnp-3528	13	120	,	,	PUNCT
fnp-3528	13	121	camp	camp	NOUN
fnp-3528	13	122	cyclic	cyclic	ADJ
fnp-3528	13	123	adenosine	adenosine	NOUN
fnp-3528	13	124	monophosphate	monophosphate	NOUN
fnp-3528	13	125	,	,	PUNCT
fnp-3528	13	126	cftr	cftr	NOUN
fnp-3528	13	127	cystic	cystic	ADJ
fnp-3528	13	128	fibrosis	fibrosis	NOUN
fnp-3528	13	129	transmembrane	transmembrane	NOUN
fnp-3528	13	130	conductance	conductance	NOUN
fnp-3528	13	131	regulator	regulator	NOUN
fnp-3528	13	132	,	,	PUNCT
fnp-3528	13	133	cho	cho	PROPN
fnp-3528	13	134	chinese	chinese	PROPN
fnp-3528	13	135	hamster	hamster	PROPN
fnp-3528	13	136	ovary	ovary	NOUN
fnp-3528	13	137	,	,	PUNCT
fnp-3528	13	138	cns	cns	PROPN
fnp-3528	13	139	central	central	ADJ
fnp-3528	13	140	nervous	nervous	ADJ
fnp-3528	13	141	system	system	NOUN
fnp-3528	13	142	,	,	PUNCT
fnp-3528	13	143	cpt	cpt	PROPN
fnp-3528	13	144	-	-	PUNCT
fnp-3528	13	145	camp	camp	NOUN
fnp-3528	13	146	8-(4	8-(4	PROPN
fnp-3528	13	147	-	-	PUNCT
fnp-3528	13	148	chlorophenylthio)-camp	chlorophenylthio)-camp	PROPN
fnp-3528	13	149	,	,	PUNCT
fnp-3528	13	150	cryo	cryo	NOUN
fnp-3528	13	151	-	-	PUNCT
fnp-3528	13	152	em	em	NOUN
fnp-3528	13	153	cryogenic	cryogenic	NOUN
fnp-3528	13	154	electron	electron	NOUN
fnp-3528	13	155	microscopy	microscopy	NOUN
fnp-3528	13	156	,	,	PUNCT
fnp-3528	13	157	csf	csf	X
fnp-3528	13	158	cer	cer	NOUN
fnp-3528	13	159	-	-	ADJ
fnp-3528	13	160	ebral	ebral	ADJ
fnp-3528	13	161	spinal	spinal	NOUN
fnp-3528	13	162	fluid	fluid	NOUN
fnp-3528	13	163	,	,	PUNCT
fnp-3528	13	164	dids	did	VERB
fnp-3528	13	165	4,4’-diisothiocyano-2,2’-stilbenedisulfonic	4,4’-diisothiocyano-2,2’-stilbenedisulfonic	NUM
fnp-3528	13	166	acid	acid	NOUN
fnp-3528	13	167	,	,	PUNCT
fnp-3528	13	168	ec50	ec50	PROPN
fnp-3528	13	169	half	half	ADV
fnp-3528	13	170	-	-	PUNCT
fnp-3528	13	171	maximal	maximal	ADJ
fnp-3528	13	172	effect	effect	NOUN
fnp-3528	13	173	concentration	concentration	NOUN
fnp-3528	13	174	,	,	PUNCT
fnp-3528	13	175	ecd	ecd	PROPN
fnp-3528	13	176	extracellular	extracellular	ADJ
fnp-3528	13	177	domain	domain	NOUN
fnp-3528	13	178	,	,	PUNCT
fnp-3528	13	179	ecgc	ecgc	PROPN
fnp-3528	13	180	epigallocatechin	epigallocatechin	PROPN
fnp-3528	13	181	gallate	gallate	PROPN
fnp-3528	13	182	,	,	PUNCT
fnp-3528	13	183	ed50	ed50	PROPN
fnp-3528	13	184	half	half	ADV
fnp-3528	13	185	-	-	PUNCT
fnp-3528	13	186	maximal	maximal	ADJ
fnp-3528	13	187	effective	effective	ADJ
fnp-3528	13	188	dose	dose	NOUN
fnp-3528	13	189	,	,	PUNCT
fnp-3528	13	190	eoad	eoad	VERB
fnp-3528	13	191	early	early	ADJ
fnp-3528	13	192	-	-	PUNCT
fnp-3528	13	193	onset	onset	NOUN
fnp-3528	13	194	ad	ad	NOUN
fnp-3528	13	195	,	,	PUNCT
fnp-3528	13	196	fpd5	fpd5	ADJ
fnp-3528	13	197	fluorescigenic	fluorescigenic	ADJ
fnp-3528	13	198	pyrazoline	pyrazoline	NOUN
fnp-3528	13	199	derivative	derivative	ADJ
fnp-3528	13	200	5	5	NUM
fnp-3528	13	201	,	,	PUNCT
fnp-3528	13	202	fxr	fxr	ADJ
fnp-3528	13	203	farnesoid	farnesoid	PROPN
fnp-3528	13	204	-	-	PUNCT
fnp-3528	13	205	x	x	NOUN
fnp-3528	13	206	-	-	NOUN
fnp-3528	13	207	receptor	receptor	NOUN
fnp-3528	13	208	,	,	PUNCT
fnp-3528	13	209	gfp	gfp	PROPN
fnp-3528	13	210	green	green	ADJ
fnp-3528	13	211	fluorescent	fluorescent	PROPN
fnp-3528	13	212	protein	protein	NOUN
fnp-3528	13	213	,	,	PUNCT
fnp-3528	13	214	ggpp	ggpp	NOUN
fnp-3528	13	215	geranylgeraniol	geranylgeraniol	PROPN
fnp-3528	13	216	pyrophosphate	pyrophosphate	NOUN
fnp-3528	13	217	,	,	PUNCT
fnp-3528	13	218	gsh	gsh	PROPN
fnp-3528	13	219	reduced	reduce	VERB
fnp-3528	13	220	glutathione	glutathione	NOUN
fnp-3528	13	221	,	,	PUNCT
fnp-3528	13	222	gwas	gwas	NOUN
fnp-3528	13	223	genome	genome	NOUN
fnp-3528	13	224	-	-	PUNCT
fnp-3528	13	225	wide	wide	ADJ
fnp-3528	13	226	association	association	NOUN
fnp-3528	13	227	study	study	NOUN
fnp-3528	13	228	,	,	PUNCT
fnp-3528	13	229	hd	hd	PROPN
fnp-3528	13	230	huntington	huntington	PROPN
fnp-3528	13	231	’s	’s	PART
fnp-3528	13	232	disease	disease	NOUN
fnp-3528	13	233	,	,	PUNCT
fnp-3528	13	234	hdac2	hdac2	NOUN
fnp-3528	13	235	histone	histone	NOUN
fnp-3528	13	236	deacetylase	deacetylase	VERB
fnp-3528	13	237	2	2	NUM
fnp-3528	13	238	,	,	PUNCT
fnp-3528	13	239	hdl	hdl	PROPN
fnp-3528	13	240	high	high	ADJ
fnp-3528	13	241	-	-	PUNCT
fnp-3528	13	242	density	density	NOUN
fnp-3528	13	243	lipoprotein	lipoprotein	ADJ
fnp-3528	13	244	,	,	PUNCT
fnp-3528	13	245	hmg	hmg	NOUN
fnp-3528	13	246	-	-	PUNCT
fnp-3528	13	247	coa	coa	NOUN
fnp-3528	13	248	-	-	PUNCT
fnp-3528	13	249	reductase	reductase	NOUN
fnp-3528	13	250	3	3	NUM
fnp-3528	13	251	-	-	PUNCT
fnp-3528	13	252	hydroxyl-3	hydroxyl-3	NUM
fnp-3528	13	253	-	-	PUNCT
fnp-3528	13	254	methyl	methyl	NOUN
fnp-3528	13	255	glutaryl	glutaryl	NOUN
fnp-3528	13	256	-	-	PUNCT
fnp-3528	13	257	coenzyme	coenzyme	PROPN
fnp-3528	13	258	a	a	DET
fnp-3528	13	259	reductase	reductase	NOUN
fnp-3528	13	260	,	,	PUNCT
fnp-3528	13	261	hts	hts	PROPN
fnp-3528	13	262	high	high	ADJ
fnp-3528	13	263	-	-	PUNCT
fnp-3528	13	264	throughput	throughput	NOUN
fnp-3528	13	265	screening	screening	NOUN
fnp-3528	13	266	,	,	PUNCT
fnp-3528	13	267	ic50	ic50	PROPN
fnp-3528	13	268	half	half	ADJ
fnp-3528	13	269	-	-	PUNCT
fnp-3528	13	270	maximal	maximal	ADJ
fnp-3528	13	271	inhibition	inhibition	NOUN
fnp-3528	13	272	concentration	concentration	NOUN
fnp-3528	13	273	,	,	PUNCT
fnp-3528	13	274	lamp1	lamp1	PROPN
fnp-3528	13	275	lysosomal	lysosomal	NOUN
fnp-3528	13	276	-	-	PUNCT
fnp-3528	13	277	associated	associate	VERB
fnp-3528	13	278	membrane	membrane	NOUN
fnp-3528	13	279	protein	protein	NOUN
fnp-3528	13	280	1	1	NUM
fnp-3528	13	281	,	,	PUNCT
fnp-3528	13	282	ldlr	ldlr	ADJ
fnp-3528	13	283	ldr	ldr	PROPN
fnp-3528	13	284	receptor	receptor	NOUN
fnp-3528	13	285	,	,	PUNCT
fnp-3528	13	286	lncrna	lncrna	NOUN
fnp-3528	13	287	long	long	ADJ
fnp-3528	13	288	non	non	ADJ
fnp-3528	13	289	-	-	ADJ
fnp-3528	13	290	coding	code	VERB
fnp-3528	13	291	rna	rna	NOUN
fnp-3528	13	292	,	,	PUNCT
fnp-3528	13	293	load	load	VERB
fnp-3528	13	294	late	late	ADJ
fnp-3528	13	295	-	-	PUNCT
fnp-3528	13	296	onset	onset	NOUN
fnp-3528	13	297	ad	ad	NOUN
fnp-3528	13	298	,	,	PUNCT
fnp-3528	13	299	ltc4	ltc4	PROPN
fnp-3528	13	300	leukotriene	leukotriene	PROPN
fnp-3528	13	301	c4	c4	PROPN
fnp-3528	13	302	,	,	PUNCT
fnp-3528	13	303	lxr	lxr	NOUN
fnp-3528	13	304	liver	liver	NOUN
fnp-3528	13	305	-	-	PUNCT
fnp-3528	13	306	x	x	NOUN
fnp-3528	13	307	-	-	NOUN
fnp-3528	13	308	receptor	receptor	NOUN
fnp-3528	13	309	,	,	PUNCT
fnp-3528	13	310	mdr	mdr	PROPN
fnp-3528	13	311	multidrug	multidrug	NOUN
fnp-3528	13	312	resistance	resistance	NOUN
fnp-3528	13	313	,	,	PUNCT
fnp-3528	13	314	mrna	mrna	PROPN
fnp-3528	13	315	messenger	messenger	PROPN
fnp-3528	13	316	rna	rna	PROPN
fnp-3528	13	317	,	,	PUNCT
fnp-3528	13	318	ms	ms	PROPN
fnp-3528	13	319	multiple	multiple	ADJ
fnp-3528	13	320	sclerosis	sclerosis	NOUN
fnp-3528	13	321	,	,	PUNCT
fnp-3528	13	322	msd	msd	NOUN
fnp-3528	13	323	membrane	membrane	NOUN
fnp-3528	13	324	-	-	PUNCT
fnp-3528	13	325	spanning	span	VERB
fnp-3528	13	326	domain	domain	NOUN
fnp-3528	13	327	,	,	PUNCT
fnp-3528	13	328	nbd	nbd	PROPN
fnp-3528	13	329	7	7	NUM
fnp-3528	13	330	-	-	PUNCT
fnp-3528	13	331	nitro-2,1,3	nitro-2,1,3	ADJ
fnp-3528	13	332	-	-	PUNCT
fnp-3528	13	333	benzooxadiazole	benzooxadiazole	NOUN
fnp-3528	13	334	or	or	CCONJ
fnp-3528	13	335	nucleotide	nucleotide	ADJ
fnp-3528	13	336	binding	bind	VERB
fnp-3528	13	337	domain	domain	NOUN
fnp-3528	13	338	,	,	PUNCT
fnp-3528	13	339	ndea	ndea	NOUN
fnp-3528	13	340	n	n	CCONJ
fnp-3528	13	341	-	-	PUNCT
fnp-3528	13	342	nitrosodiethylamine	nitrosodiethylamine	NOUN
fnp-3528	13	343	,	,	PUNCT
fnp-3528	13	344	nem	nem	PROPN
fnp-3528	13	345	n	n	CCONJ
fnp-3528	13	346	-	-	PUNCT
fnp-3528	13	347	ethylmaleimide	ethylmaleimide	ADV
fnp-3528	13	348	,	,	PUNCT
fnp-3528	13	349	(	(	PUNCT
fnp-3528	13	350	ox)ldl	ox)ldl	NOUN
fnp-3528	13	351	(	(	PUNCT
fnp-3528	13	352	oxidized	oxidize	VERB
fnp-3528	13	353	)	)	PUNCT
fnp-3528	13	354	low	low	ADJ
fnp-3528	13	355	density	density	NOUN
fnp-3528	13	356	lipoprotein	lipoprotein	ADJ
fnp-3528	13	357	,	,	PUNCT
fnp-3528	13	358	pcb29	pcb29	NOUN
fnp-3528	13	359	-	-	PROPN
fnp-3528	13	360	pq	pq	NOUN
fnp-3528	13	361	2,3,5	2,3,5	NUM
fnp-3528	13	362	-	-	PUNCT
fnp-3528	13	363	trichloro-6	trichloro-6	PRON
fnp-3528	13	364	-	-	PUNCT
fnp-3528	13	365	phenyl-[1,4]-benzoquinone	phenyl-[1,4]-benzoquinone	NOUN
fnp-3528	13	366	,	,	PUNCT
fnp-3528	13	367	pd	pd	PROPN
fnp-3528	13	368	parkinson	parkinson	NOUN
fnp-3528	13	369	’s	’s	PART
fnp-3528	13	370	disease	disease	NOUN
fnp-3528	13	371	,	,	PUNCT
fnp-3528	13	372	pdb	pdb	PROPN
fnp-3528	13	373	protein	protein	NOUN
fnp-3528	13	374	data	data	PROPN
fnp-3528	13	375	bank	bank	PROPN
fnp-3528	13	376	,	,	PUNCT
fnp-3528	13	377	pg	pg	PROPN
fnp-3528	13	378	-	-	PUNCT
fnp-3528	13	379	j2	j2	NOUN
fnp-3528	13	380	prostaglandin	prostaglandin	NOUN
fnp-3528	13	381	j2	j2	PROPN
fnp-3528	13	382	,	,	PUNCT
fnp-3528	13	383	pma	pma	PROPN
fnp-3528	13	384	phorbol	phorbol	PROPN
fnp-3528	13	385	12	12	NUM
fnp-3528	13	386	-	-	PUNCT
fnp-3528	13	387	myristate	myristate	ADJ
fnp-3528	13	388	13	13	NUM
fnp-3528	13	389	-	-	PUNCT
fnp-3528	13	390	acetate	acetate	NOUN
fnp-3528	13	391	,	,	PUNCT
fnp-3528	13	392	ppar	ppar	NOUN
fnp-3528	13	393	peroxisome	peroxisome	VERB
fnp-3528	13	394	proliferator	proliferator	NOUN
fnp-3528	13	395	-	-	PUNCT
fnp-3528	13	396	activated	activate	VERB
fnp-3528	13	397	receptor	receptor	NOUN
fnp-3528	13	398	,	,	PUNCT
fnp-3528	13	399	prdx1	prdx1	PROPN
fnp-3528	13	400	peroxiredoxin	peroxiredoxin	PROPN
fnp-3528	13	401	1	1	NUM
fnp-3528	13	402	,	,	PUNCT
fnp-3528	13	403	rar	rar	NOUN
fnp-3528	13	404	retinoic	retinoic	ADJ
fnp-3528	13	405	acid	acid	NOUN
fnp-3528	13	406	receptor	receptor	NOUN
fnp-3528	13	407	,	,	PUNCT
fnp-3528	13	408	rna	rna	NOUN
fnp-3528	13	409	ribonucleic	ribonucleic	NOUN
fnp-3528	13	410	acid	acid	NOUN
fnp-3528	13	411	,	,	PUNCT
fnp-3528	13	412	rxr	rxr	PROPN
fnp-3528	13	413	retinoid	retinoid	PROPN
fnp-3528	13	414	-	-	PUNCT
fnp-3528	13	415	x	x	NOUN
fnp-3528	13	416	-	-	NOUN
fnp-3528	13	417	receptor	receptor	NOUN
fnp-3528	13	418	,	,	PUNCT
fnp-3528	13	419	sar	sar	NOUN
fnp-3528	13	420	structure	structure	NOUN
fnp-3528	13	421	-	-	PUNCT
fnp-3528	13	422	activity	activity	NOUN
fnp-3528	13	423	relationships	relationship	NOUN
fnp-3528	13	424	,	,	PUNCT
fnp-3528	13	425	shrna	shrna	ADJ
fnp-3528	13	426	short	short	ADJ
fnp-3528	13	427	-	-	PUNCT
fnp-3528	13	428	hairpin	hairpin	NOUN
fnp-3528	13	429	rna	rna	NOUN
fnp-3528	13	430	,	,	PUNCT
fnp-3528	13	431	sirna	sirna	PROPN
fnp-3528	13	432	small	small	ADJ
fnp-3528	13	433	interfering	interfere	VERB
fnp-3528	13	434	rna	rna	PROPN
fnp-3528	13	435	,	,	PUNCT
fnp-3528	13	436	snp	snp	ADJ
fnp-3528	13	437	single	single	ADJ
fnp-3528	13	438	nucleotide	nucleotide	NOUN
fnp-3528	13	439	polymorphism	polymorphism	NOUN
fnp-3528	13	440	,	,	PUNCT
fnp-3528	13	441	sr	sr	PROPN
fnp-3528	13	442	-	-	PUNCT
fnp-3528	13	443	bi	bi	PROPN
fnp-3528	13	444	(	(	PUNCT
fnp-3528	13	445	srb1	srb1	PROPN
fnp-3528	13	446	)	)	PUNCT
fnp-3528	13	447	scavenger	scavenger	NOUN
fnp-3528	13	448	receptor	receptor	NOUN
fnp-3528	13	449	b1	b1	NOUN
fnp-3528	13	450	(	(	PUNCT
fnp-3528	13	451	also	also	ADV
fnp-3528	13	452	hdl	hdl	PROPN
fnp-3528	13	453	receptor	receptor	PROPN
fnp-3528	13	454	)	)	PUNCT
fnp-3528	13	455	,	,	PUNCT
fnp-3528	13	456	srepb	srepb	VERB
fnp-3528	13	457	sterol	sterol	NOUN
fnp-3528	13	458	regulation	regulation	NOUN
fnp-3528	13	459	element	element	NOUN
fnp-3528	13	460	-	-	PUNCT
fnp-3528	13	461	binding	bind	VERB
fnp-3528	13	462	protein	protein	NOUN
fnp-3528	13	463	,	,	PUNCT
fnp-3528	13	464	tki	tki	PROPN
fnp-3528	13	465	tyrosine	tyrosine	PROPN
fnp-3528	13	466	kinase	kinase	PROPN
fnp-3528	13	467	inhibitor	inhibitor	PROPN
fnp-3528	13	468	,	,	PUNCT
fnp-3528	13	469	tki	tki	PROPN
fnp-3528	13	470	tyrosine	tyrosine	PROPN
fnp-3528	13	471	kinase	kinase	PROPN
fnp-3528	13	472	inhibitor	inhibitor	PROPN
fnp-3528	13	473	,	,	PUNCT
fnp-3528	13	474	tm	tm	DET
fnp-3528	13	475	transmembrane	transmembrane	ADJ
fnp-3528	13	476	helix	helix	NOUN
fnp-3528	13	477	introduction	introduction	NOUN
fnp-3528	13	478	from	from	ADP
fnp-3528	13	479	mdr	mdr	PROPN
fnp-3528	13	480	to	to	ADP
fnp-3528	13	481	neurodegeneration	neurodegeneration	NOUN
fnp-3528	13	482	:	:	PUNCT
fnp-3528	13	483	abc	abc	PROPN
fnp-3528	13	484	transporters	transporter	NOUN
fnp-3528	13	485	in	in	ADP
fnp-3528	13	486	human	human	ADJ
fnp-3528	13	487	disease	disease	NOUN
fnp-3528	13	488	abc	abc	PROPN
fnp-3528	13	489	transporters	transporter	NOUN
fnp-3528	13	490	are	be	AUX
fnp-3528	13	491	membrane	membrane	NOUN
fnp-3528	13	492	-	-	PUNCT
fnp-3528	13	493	bound	bind	VERB
fnp-3528	13	494	transport	transport	NOUN
fnp-3528	13	495	proteins	protein	NOUN
fnp-3528	13	496	that	that	PRON
fnp-3528	13	497	are	be	AUX
fnp-3528	13	498	ubiquitously	ubiquitously	ADV
fnp-3528	13	499	present	present	ADJ
fnp-3528	13	500	in	in	ADP
fnp-3528	13	501	the	the	DET
fnp-3528	13	502	human	human	NOUN
fnp-3528	13	503	body.1	body.1	PROPN
fnp-3528	13	504	-	-	PUNCT
fnp-3528	13	505	4	4	NUM
fnp-3528	13	506	they	they	PRON
fnp-3528	13	507	play	play	VERB
fnp-3528	13	508	a	a	DET
fnp-3528	13	509	major	major	ADJ
fnp-3528	13	510	role	role	NOUN
fnp-3528	13	511	in	in	ADP
fnp-3528	13	512	determining	determine	VERB
fnp-3528	13	513	the	the	DET
fnp-3528	13	514	distribution	distribution	NOUN
fnp-3528	13	515	of	of	ADP
fnp-3528	13	516	intrinsic	intrinsic	ADJ
fnp-3528	13	517	and	and	CCONJ
fnp-3528	13	518	xenobiotic	xenobiotic	ADJ
fnp-3528	13	519	drugs	drug	NOUN
fnp-3528	13	520	between	between	ADP
fnp-3528	13	521	intraand	intraand	NOUN
fnp-3528	13	522	intercellular	intercellular	ADJ
fnp-3528	13	523	compartments.5,6	compartments.5,6	VERB
fnp-3528	13	524	the	the	DET
fnp-3528	13	525	clinical	clinical	ADJ
fnp-3528	13	526	relevance	relevance	NOUN
fnp-3528	13	527	of	of	ADP
fnp-3528	13	528	abc	abc	PROPN
fnp-3528	13	529	transporters	transporter	NOUN
fnp-3528	13	530	became	became	AUX
fnp-3528	13	531	pronounced	pronounce	VERB
fnp-3528	13	532	when	when	SCONJ
fnp-3528	13	533	their	their	PRON
fnp-3528	13	534	expression	expression	NOUN
fnp-3528	13	535	was	be	AUX
fnp-3528	13	536	correlated	correlate	VERB
fnp-3528	13	537	to	to	ADP
fnp-3528	13	538	cross	cross	NOUN
fnp-3528	13	539	-	-	NOUN
fnp-3528	13	540	resistance	resistance	NOUN
fnp-3528	13	541	of	of	ADP
fnp-3528	13	542	cancer	cancer	NOUN
fnp-3528	13	543	cells	cell	NOUN
fnp-3528	13	544	to	to	PART
fnp-3528	13	545	antineoplastic	antineoplastic	VERB
fnp-3528	13	546	agents.3,7	agents.3,7	PROPN
fnp-3528	13	547	-	-	SYM
fnp-3528	13	548	13	13	NUM
fnp-3528	13	549	this	this	DET
fnp-3528	13	550	phenomenon	phenomenon	NOUN
fnp-3528	13	551	is	be	AUX
fnp-3528	13	552	called	call	VERB
fnp-3528	13	553	‘	'	PUNCT
fnp-3528	13	554	multidrug	multidrug	NOUN
fnp-3528	13	555	resistance	resistance	NOUN
fnp-3528	13	556	’	'	PUNCT
fnp-3528	13	557	(	(	PUNCT
fnp-3528	13	558	mdr	mdr	PROPN
fnp-3528	13	559	)	)	PUNCT
fnp-3528	13	560	.	.	PUNCT
fnp-3528	14	1	however	however	ADV
fnp-3528	14	2	,	,	PUNCT
fnp-3528	14	3	despite	despite	SCONJ
fnp-3528	14	4	enormous	enormous	ADJ
fnp-3528	14	5	efforts	effort	NOUN
fnp-3528	14	6	and	and	CCONJ
fnp-3528	14	7	countless	countless	ADJ
fnp-3528	14	8	clinical	clinical	ADJ
fnp-3528	14	9	trials	trial	NOUN
fnp-3528	14	10	to	to	PART
fnp-3528	14	11	target	target	VERB
fnp-3528	14	12	these	these	DET
fnp-3528	14	13	efflux	efflux	NOUN
fnp-3528	14	14	pumps,14	pumps,14	NOUN
fnp-3528	14	15	-	-	PUNCT
fnp-3528	14	16	17	17	NUM
fnp-3528	14	17	mdr	mdr	NOUN
fnp-3528	14	18	is	be	AUX
fnp-3528	14	19	still	still	ADV
fnp-3528	14	20	a	a	DET
fnp-3528	14	21	major	major	ADJ
fnp-3528	14	22	unresolved	unresolved	ADJ
fnp-3528	14	23	obstacle	obstacle	NOUN
fnp-3528	14	24	in	in	ADP
fnp-3528	14	25	cancer	cancer	NOUN
fnp-3528	14	26	chemotherapy	chemotherapy	NOUN
fnp-3528	14	27	.	.	PUNCT
fnp-3528	15	1	to	to	ADP
fnp-3528	15	2	date	date	NOUN
fnp-3528	15	3	,	,	PUNCT
fnp-3528	15	4	most	most	ADJ
fnp-3528	15	5	abc	abc	PROPN
fnp-3528	15	6	transporters	transporter	NOUN
fnp-3528	15	7	have	have	AUX
fnp-3528	15	8	been	be	AUX
fnp-3528	15	9	associated	associate	VERB
fnp-3528	15	10	with	with	ADP
fnp-3528	15	11	mdr,3,7	mdr,3,7	PROPN
fnp-3528	15	12	-	-	PUNCT
fnp-3528	15	13	9,11,12	9,11,12	PROPN
fnp-3528	15	14	but	but	CCONJ
fnp-3528	15	15	only	only	ADV
fnp-3528	15	16	a	a	DET
fnp-3528	15	17	small	small	ADJ
fnp-3528	15	18	minority	minority	NOUN
fnp-3528	15	19	has	have	AUX
fnp-3528	15	20	been	be	AUX
fnp-3528	15	21	studied	study	VERB
fnp-3528	15	22	properly	properly	ADV
fnp-3528	15	23	and	and	CCONJ
fnp-3528	15	24	can	can	AUX
fnp-3528	15	25	be	be	AUX
fnp-3528	15	26	addressed	address	VERB
fnp-3528	15	27	by	by	ADP
fnp-3528	15	28	small	small	ADJ
fnp-3528	15	29	-	-	PUNCT
fnp-3528	15	30	molecule	molecule	NOUN
fnp-3528	15	31	modulators.18	modulators.18	NOUN
fnp-3528	15	32	-	-	PUNCT
fnp-3528	15	33	22	22	NUM
fnp-3528	15	34	amongst	amongst	ADP
fnp-3528	15	35	these	these	PRON
fnp-3528	15	36	are	be	AUX
fnp-3528	15	37	abcb1,1,18	abcb1,1,18	NOUN
fnp-3528	15	38	-	-	PUNCT
fnp-3528	15	39	27	27	NUM
fnp-3528	15	40	abcc1,1,18,19,23,24,26,27	abcc1,1,18,19,23,24,26,27	NOUN
fnp-3528	15	41	and	and	CCONJ
fnp-3528	15	42	abcg2.18,19,25	abcg2.18,19,25	ADV
fnp-3528	15	43	apart	apart	ADV
fnp-3528	15	44	from	from	ADP
fnp-3528	15	45	their	their	PRON
fnp-3528	15	46	role	role	NOUN
fnp-3528	15	47	in	in	ADP
fnp-3528	15	48	multidrug	multidrug	NOUN
fnp-3528	15	49	-	-	PUNCT
fnp-3528	15	50	resistant	resistant	ADJ
fnp-3528	15	51	cancer	cancer	NOUN
fnp-3528	15	52	,	,	PUNCT
fnp-3528	15	53	many	many	ADJ
fnp-3528	15	54	abc	abc	PROPN
fnp-3528	15	55	transporters	transporter	NOUN
fnp-3528	15	56	have	have	AUX
fnp-3528	15	57	been	be	AUX
fnp-3528	15	58	identified	identify	VERB
fnp-3528	15	59	as	as	ADP
fnp-3528	15	60	key	key	ADJ
fnp-3528	15	61	players	player	NOUN
fnp-3528	15	62	in	in	ADP
fnp-3528	15	63	neurological	neurological	ADJ
fnp-3528	15	64	disorders	disorder	NOUN
fnp-3528	15	65	.	.	PUNCT
fnp-3528	16	1	evidence	evidence	NOUN
fnp-3528	16	2	for	for	ADP
fnp-3528	16	3	this	this	PRON
fnp-3528	16	4	includes	include	VERB
fnp-3528	16	5	their	their	PRON
fnp-3528	16	6	high	high	ADJ
fnp-3528	16	7	abundance	abundance	NOUN
fnp-3528	16	8	at	at	ADP
fnp-3528	16	9	the	the	DET
fnp-3528	16	10	blood	blood	NOUN
fnp-3528	16	11	-	-	PUNCT
fnp-3528	16	12	brain	brain	NOUN
fnp-3528	16	13	barrier	barrier	NOUN
fnp-3528	16	14	(	(	PUNCT
fnp-3528	16	15	bbb	bbb	NOUN
fnp-3528	16	16	)	)	PUNCT
fnp-3528	16	17	and	and	CCONJ
fnp-3528	16	18	blood	blood	NOUN
fnp-3528	16	19	-	-	PUNCT
fnp-3528	16	20	cerebrospinal	cerebrospinal	ADJ
fnp-3528	16	21	fluid	fluid	NOUN
fnp-3528	16	22	barrier	barrier	NOUN
fnp-3528	16	23	(	(	PUNCT
fnp-3528	16	24	bcsfb	bcsfb	PROPN
fnp-3528	16	25	)	)	PUNCT
fnp-3528	16	26	in	in	ADP
fnp-3528	16	27	the	the	DET
fnp-3528	16	28	central	central	ADJ
fnp-3528	16	29	nervous	nervous	ADJ
fnp-3528	16	30	system	system	NOUN
fnp-3528	16	31	(	(	PUNCT
fnp-3528	16	32	cns).28	cns).28	ADV
fnp-3528	16	33	-	-	PUNCT
fnp-3528	16	34	32	32	NUM
fnp-3528	16	35	additionally	additionally	ADV
fnp-3528	16	36	,	,	PUNCT
fnp-3528	16	37	their	their	PRON
fnp-3528	16	38	expression	expression	NOUN
fnp-3528	16	39	is	be	AUX
fnp-3528	16	40	altered	alter	VERB
fnp-3528	16	41	in	in	ADP
fnp-3528	16	42	many	many	ADJ
fnp-3528	16	43	pathological	pathological	ADJ
fnp-3528	16	44	conditions	condition	NOUN
fnp-3528	16	45	in	in	ADP
fnp-3528	16	46	the	the	DET
fnp-3528	16	47	brain.28	brain.28	NOUN
fnp-3528	16	48	-	-	PUNCT
fnp-3528	16	49	30,33	30,33	NUM
fnp-3528	16	50	-	-	PUNCT
fnp-3528	16	51	40	40	NUM
fnp-3528	16	52	important	important	ADJ
fnp-3528	16	53	players	player	NOUN
fnp-3528	16	54	are	be	AUX
fnp-3528	16	55	,	,	PUNCT
fnp-3528	16	56	again	again	ADV
fnp-3528	16	57	,	,	PUNCT
fnp-3528	16	58	abcb1,28	abcb1,28	ADJ
fnp-3528	16	59	-	-	ADJ
fnp-3528	16	60	30,34	30,34	ADJ
fnp-3528	16	61	-	-	PUNCT
fnp-3528	16	62	36,39	36,39	ADJ
fnp-3528	16	63	-	-	PUNCT
fnp-3528	16	64	44	44	NUM
fnp-3528	16	65	abcc1,28	abcc1,28	NOUN
fnp-3528	16	66	-	-	PUNCT
fnp-3528	16	67	30,39,41,43,45	30,39,41,43,45	PROPN
fnp-3528	16	68	and	and	CCONJ
fnp-3528	16	69	abcg228,30,34,36,39	abcg228,30,34,36,39	ADV
fnp-3528	16	70	-	-	PUNCT
fnp-3528	16	71	41,43	41,43	ADJ
fnp-3528	16	72	in	in	ADP
fnp-3528	16	73	diseases	disease	NOUN
fnp-3528	16	74	like	like	ADP
fnp-3528	16	75	ad,28	ad,28	ADV
fnp-3528	16	76	-	-	PUNCT
fnp-3528	16	77	30,41	30,41	NUM
fnp-3528	16	78	amyotrophic	amyotrophic	ADJ
fnp-3528	16	79	lateral	lateral	ADJ
fnp-3528	16	80	sclerosis	sclerosis	NOUN
fnp-3528	16	81	(	(	PUNCT
fnp-3528	16	82	als),34,36,44	als),34,36,44	PROPN
fnp-3528	16	83	encephalopathy,45,46	encephalopathy,45,46	PROPN
fnp-3528	16	84	epilepsy,39,40	epilepsy,39,40	X
fnp-3528	16	85	multiple	multiple	ADJ
fnp-3528	16	86	sclerosis	sclerosis	NOUN
fnp-3528	16	87	(	(	PUNCT
fnp-3528	16	88	ms),35	ms),35	PUNCT
fnp-3528	16	89	and	and	CCONJ
fnp-3528	16	90	parkinson	parkinson	NOUN
fnp-3528	16	91	’s	’s	PART
fnp-3528	16	92	disease	disease	NOUN
fnp-3528	16	93	(	(	PUNCT
fnp-3528	16	94	pd).42,47	pd).42,47	ADV
fnp-3528	16	95	furthermore	furthermore	ADV
fnp-3528	16	96	,	,	PUNCT
fnp-3528	16	97	abc	abc	PROPN
fnp-3528	16	98	transporters	transporter	NOUN
fnp-3528	16	99	were	be	AUX
fnp-3528	16	100	also	also	ADV
fnp-3528	16	101	found	find	VERB
fnp-3528	16	102	to	to	PART
fnp-3528	16	103	be	be	AUX
fnp-3528	16	104	associated	associate	VERB
fnp-3528	16	105	with	with	ADP
fnp-3528	16	106	certain	certain	ADJ
fnp-3528	16	107	genetic	genetic	ADJ
fnp-3528	16	108	neurological	neurological	ADJ
fnp-3528	16	109	and	and	CCONJ
fnp-3528	16	110	psychiatric	psychiatric	ADJ
fnp-3528	16	111	diseases	disease	NOUN
fnp-3528	16	112	such	such	ADJ
fnp-3528	16	113	as	as	ADP
fnp-3528	16	114	huntington	huntington	PROPN
fnp-3528	16	115	’s	’s	PART
fnp-3528	16	116	disease	disease	NOUN
fnp-3528	16	117	(	(	PUNCT
fnp-3528	16	118	hd),38	hd),38	VERB
fnp-3528	16	119	bipolar	bipolar	ADJ
fnp-3528	16	120	disorder,48,49	disorder,48,49	VERB
fnp-3528	16	121	depression,48	depression,48	NOUN
fnp-3528	16	122	or	or	CCONJ
fnp-3528	16	123	schizophrenia.48,49	schizophrenia.48,49	NOUN
fnp-3528	16	124	table	table	NOUN
fnp-3528	16	125	 	 	SPACE
fnp-3528	16	126	1	1	NUM
fnp-3528	16	127	summarizes	summarize	VERB
fnp-3528	16	128	the	the	DET
fnp-3528	16	129	involvement	involvement	NOUN
fnp-3528	16	130	of	of	ADP
fnp-3528	16	131	abc	abc	PROPN
fnp-3528	16	132	transporters	transporter	NOUN
fnp-3528	16	133	in	in	ADP
fnp-3528	16	134	neurological	neurological	ADJ
fnp-3528	16	135	diseases	disease	NOUN
fnp-3528	16	136	.	.	PUNCT
fnp-3528	17	1	table	table	NOUN
fnp-3528	17	2	 	 	SPACE
fnp-3528	17	3	1	1	NUM
fnp-3528	17	4	.	.	PUNCT
fnp-3528	18	1	abc	abc	PROPN
fnp-3528	18	2	transporters	transporter	NOUN
fnp-3528	18	3	and	and	CCONJ
fnp-3528	18	4	related	relate	VERB
fnp-3528	18	5	neurological	neurological	ADJ
fnp-3528	18	6	and	and	CCONJ
fnp-3528	18	7	psychiatric	psychiatric	ADJ
fnp-3528	18	8	diseases	disease	NOUN
fnp-3528	18	9	.	.	PUNCT
fnp-3528	19	1	abc	abc	PROPN
fnp-3528	19	2	transporter	transporter	VERB
fnp-3528	19	3	associated	associate	VERB
fnp-3528	19	4	diseases	disease	NOUN
fnp-3528	19	5	abca1	abca1	NOUN
fnp-3528	20	1	ad50	ad50	PROPN
fnp-3528	20	2	hd51	hd51	PROPN
fnp-3528	20	3	abca2	abca2	VERB
fnp-3528	21	1	ad52	ad52	PROPN
fnp-3528	21	2	abnormal	abnormal	ADJ
fnp-3528	21	3	sphingolipid	sphingolipid	NOUN
fnp-3528	21	4	metabolism53,54	metabolism53,54	PROPN
fnp-3528	21	5	abca4	abca4	VERB
fnp-3528	21	6	cone	cone	NOUN
fnp-3528	21	7	-	-	PUNCT
fnp-3528	21	8	rod	rod	NOUN
fnp-3528	21	9	dystrophy55	dystrophy55	NOUN
fnp-3528	21	10	fundus	fundus	NOUN
fnp-3528	21	11	flavimaculatus56	flavimaculatus56	NOUN
fnp-3528	21	12	retinitis	retinitis	ADJ
fnp-3528	21	13	pigmentosa57,58	pigmentosa57,58	NUM
fnp-3528	21	14	stargardt	stargardt	ADJ
fnp-3528	21	15	disease59	disease59	NOUN
fnp-3528	21	16	-	-	PUNCT
fnp-3528	21	17	62	62	NUM
fnp-3528	21	18	abca5	abca5	X
fnp-3528	22	1	ad28	ad28	PROPN
fnp-3528	22	2	abca7	abca7	PROPN
fnp-3528	22	3	ad63	ad63	PROPN
fnp-3528	22	4	abca13	abca13	VERB
fnp-3528	22	5	lewy	lewy	PROPN
fnp-3528	22	6	body	body	PROPN
fnp-3528	22	7	disease64	disease64	VERB
fnp-3528	22	8	psychiatric	psychiatric	ADJ
fnp-3528	22	9	disorders48,65,66	disorders48,65,66	ADJ
fnp-3528	22	10	stroke	stroke	PROPN
fnp-3528	22	11	in	in	ADP
fnp-3528	22	12	mice67	mice67	ADJ
fnp-3528	22	13	abcb1	abcb1	NOUN
fnp-3528	23	1	ad28	ad28	PROPN
fnp-3528	23	2	brain	brain	PROPN
fnp-3528	23	3	tumors68	tumors68	ADP
fnp-3528	23	4	hiv	hiv	PROPN
fnp-3528	23	5	-	-	PUNCT
fnp-3528	23	6	associated	associate	VERB
fnp-3528	23	7	depression	depression	NOUN
fnp-3528	23	8	and	and	CCONJ
fnp-3528	23	9	schizophrenia69,70	schizophrenia69,70	PROPN
fnp-3528	23	10	hiv	hiv	PROPN
fnp-3528	23	11	-	-	PUNCT
fnp-3528	23	12	associated	associate	VERB
fnp-3528	23	13	encephalopathy46	encephalopathy46	NOUN
fnp-3528	23	14	epilepsy71	epilepsy71	PROPN
fnp-3528	23	15	ischemic	ischemic	ADJ
fnp-3528	23	16	stroke72	stroke72	NOUN
fnp-3528	24	1	ms35	ms35	PROPN
fnp-3528	24	2	multiple	multiple	ADJ
fnp-3528	24	3	systems	system	NOUN
fnp-3528	24	4	atrophy73	atrophy73	NOUN
fnp-3528	25	1	pd74	pd74	PROPN
fnp-3528	25	2	progressive	progressive	ADJ
fnp-3528	25	3	supranuclear	supranuclear	PROPN
fnp-3528	25	4	palsy75	palsy75	PROPN
fnp-3528	25	5	creutzfeldt	creutzfeldt	PROPN
fnp-3528	25	6	-	-	PUNCT
fnp-3528	25	7	jakob	jakob	ADJ
fnp-3528	25	8	disease76	disease76	PROPN
fnp-3528	25	9	abcb7	abcb7	PUNCT
fnp-3528	26	1	pd77	pd77	ADJ
fnp-3528	26	2	abcb9	abcb9	VERB
fnp-3528	26	3	pd78	pd78	PROPN
fnp-3528	26	4	abcc1	abcc1	NOUN
fnp-3528	27	1	ad28	ad28	PROPN
fnp-3528	27	2	brain	brain	NOUN
fnp-3528	27	3	tumors79	tumors79	NOUN
fnp-3528	27	4	epilepsy39	epilepsy39	NOUN
fnp-3528	27	5	hiv	hiv	PROPN
fnp-3528	27	6	-	-	PUNCT
fnp-3528	27	7	associated	associate	VERB
fnp-3528	27	8	encephalopathy45	encephalopathy45	NOUN
fnp-3528	27	9	ischemic	ischemic	ADJ
fnp-3528	27	10	stroke80	stroke80	NOUN
fnp-3528	27	11	abcc2	abcc2	NOUN
fnp-3528	27	12	brain	brain	NOUN
fnp-3528	27	13	tumors79	tumors79	ADJ
fnp-3528	27	14	epilepsy39	epilepsy39	NOUN
fnp-3528	27	15	abcc3	abcc3	PROPN
fnp-3528	28	1	brain	brain	NOUN
fnp-3528	28	2	tumors79	tumors79	ADJ
fnp-3528	28	3	epilepsy39	epilepsy39	NOUN
fnp-3528	28	4	abcc8	abcc8	PROPN
fnp-3528	28	5	als81	als81	PROPN
fnp-3528	28	6	abcc9	abcc9	PROPN
fnp-3528	28	7	als81	als81	PROPN
fnp-3528	28	8	limbic	limbic	NOUN
fnp-3528	28	9	-	-	PUNCT
fnp-3528	28	10	predominant	predominant	ADJ
fnp-3528	28	11	age	age	NOUN
fnp-3528	28	12	-	-	PUNCT
fnp-3528	28	13	related	relate	VERB
fnp-3528	28	14	tdp-43	tdp-43	NOUN
fnp-3528	28	15	encephalopathy	encephalopathy	ADJ
fnp-3528	28	16	(	(	PUNCT
fnp-3528	28	17	late)82	late)82	ADJ
fnp-3528	28	18	hippocampal	hippocampal	ADJ
fnp-3528	28	19	sclerosis	sclerosis	NOUN
fnp-3528	28	20	of	of	ADP
fnp-3528	28	21	aging	aging	NOUN
fnp-3528	28	22	and	and	CCONJ
fnp-3528	28	23	depression83	depression83	NOUN
fnp-3528	28	24	abcd1	abcd1	ADJ
fnp-3528	28	25	cerebral	cerebral	ADJ
fnp-3528	28	26	adrenoleukodystrophy84	adrenoleukodystrophy84	NOUN
fnp-3528	28	27	abcg1	abcg1	PUNCT
fnp-3528	29	1	ad85	ad85	PROPN
fnp-3528	29	2	brain	brain	NOUN
fnp-3528	29	3	metabolic	metabolic	NOUN
fnp-3528	29	4	disorder86	disorder86	NOUN
fnp-3528	29	5	abcg2	abcg2	PUNCT
fnp-3528	30	1	ad87	ad87	NOUN
fnp-3528	30	2	als88	als88	PROPN
fnp-3528	30	3	brain	brain	NOUN
fnp-3528	30	4	tumors89	tumors89	NOUN
fnp-3528	30	5	epilepsy90	epilepsy90	NOUN
fnp-3528	30	6	ms91	ms91	PROPN
fnp-3528	30	7	pd47	pd47	PROPN
fnp-3528	30	8	traumatic	traumatic	ADJ
fnp-3528	30	9	brain	brain	NOUN
fnp-3528	30	10	injury92	injury92	NOUN
fnp-3528	30	11	abcg4	abcg4	PUNCT
fnp-3528	31	1	ad93	ad93	PROPN
fnp-3528	31	2	hd51	hd51	PROPN
fnp-3528	31	3	abc	abc	PROPN
fnp-3528	31	4	transporters	transporter	NOUN
fnp-3528	31	5	,	,	PUNCT
fnp-3528	31	6	aβ	aβ	DET
fnp-3528	31	7	proteins	protein	NOUN
fnp-3528	31	8	,	,	PUNCT
fnp-3528	31	9	and	and	CCONJ
fnp-3528	31	10	ad	ad	NOUN
fnp-3528	31	11	since	since	SCONJ
fnp-3528	31	12	2001	2001	NUM
fnp-3528	31	13	,	,	PUNCT
fnp-3528	31	14	abc	abc	PROPN
fnp-3528	31	15	transporters	transporter	NOUN
fnp-3528	31	16	have	have	AUX
fnp-3528	31	17	been	be	AUX
fnp-3528	31	18	implicated	implicate	VERB
fnp-3528	31	19	in	in	ADP
fnp-3528	31	20	ad	ad	NOUN
fnp-3528	31	21	pathogenesis.28	pathogenesis.28	NOUN
fnp-3528	31	22	-	-	PUNCT
fnp-3528	31	23	30,41,43,94,95	30,41,43,94,95	NUM
fnp-3528	31	24	specifically	specifically	ADV
fnp-3528	31	25	abcb1,94	abcb1,94	PROPN
fnp-3528	31	26	abcc1,96	abcc1,96	NOUN
fnp-3528	32	1	and	and	CCONJ
fnp-3528	32	2	abcg297	abcg297	PROPN
fnp-3528	32	3	have	have	AUX
fnp-3528	32	4	been	be	AUX
fnp-3528	32	5	suggested	suggest	VERB
fnp-3528	32	6	to	to	PART
fnp-3528	32	7	directly	directly	ADV
fnp-3528	32	8	transport	transport	VERB
fnp-3528	32	9	amyloid	amyloid	NOUN
fnp-3528	32	10	-	-	PUNCT
fnp-3528	32	11	β	β	X
fnp-3528	32	12	(	(	PUNCT
fnp-3528	32	13	aβ	aβ	NOUN
fnp-3528	32	14	)	)	PUNCT
fnp-3528	32	15	proteins	protein	NOUN
fnp-3528	32	16	,	,	PUNCT
fnp-3528	32	17	being	be	AUX
fnp-3528	32	18	involved	involve	VERB
fnp-3528	32	19	in	in	ADP
fnp-3528	32	20	aβ	aβ	ADP
fnp-3528	32	21	clearance	clearance	NOUN
fnp-3528	32	22	from	from	ADP
fnp-3528	32	23	the	the	DET
fnp-3528	32	24	brain	brain	NOUN
fnp-3528	32	25	to	to	ADP
fnp-3528	32	26	the	the	DET
fnp-3528	32	27	blood	blood	NOUN
fnp-3528	32	28	stream.94,96,97	stream.94,96,97	ADV
fnp-3528	32	29	in	in	ADP
fnp-3528	32	30	light	light	NOUN
fnp-3528	32	31	of	of	ADP
fnp-3528	32	32	the	the	DET
fnp-3528	32	33	failure	failure	NOUN
fnp-3528	32	34	of	of	ADP
fnp-3528	32	35	the	the	DET
fnp-3528	32	36	first	first	ADJ
fnp-3528	32	37	immunological	immunological	ADJ
fnp-3528	32	38	treatment	treatment	NOUN
fnp-3528	32	39	studies,98	studies,98	NOUN
fnp-3528	32	40	it	it	PRON
fnp-3528	32	41	was	be	AUX
fnp-3528	32	42	already	already	ADV
fnp-3528	32	43	proposed	propose	VERB
fnp-3528	32	44	that	that	SCONJ
fnp-3528	32	45	abc	abc	PROPN
fnp-3528	32	46	transporter	transporter	VERB
fnp-3528	32	47	dysfunction	dysfunction	NOUN
fnp-3528	32	48	could	could	AUX
fnp-3528	32	49	explain	explain	VERB
fnp-3528	32	50	the	the	DET
fnp-3528	32	51	clearance	clearance	NOUN
fnp-3528	32	52	problem	problem	NOUN
fnp-3528	32	53	of	of	ADP
fnp-3528	32	54	aβ.99,100	aβ.99,100	PROPN
fnp-3528	32	55	cerebral	cerebral	ADJ
fnp-3528	32	56	accumulation	accumulation	NOUN
fnp-3528	32	57	of	of	ADP
fnp-3528	32	58	aβ	aβ	DET
fnp-3528	32	59	proteins	protein	NOUN
fnp-3528	32	60	interferes	interfere	VERB
fnp-3528	32	61	with	with	ADP
fnp-3528	32	62	neuronal	neuronal	ADJ
fnp-3528	32	63	metabolite	metabolite	NOUN
fnp-3528	32	64	homeostasis	homeostasis	NOUN
fnp-3528	32	65	and	and	CCONJ
fnp-3528	32	66	leads	lead	VERB
fnp-3528	32	67	to	to	ADP
fnp-3528	32	68	interruption	interruption	NOUN
fnp-3528	32	69	of	of	ADP
fnp-3528	32	70	cortico	cortico	NOUN
fnp-3528	32	71	-	-	PUNCT
fnp-3528	32	72	cortical	cortical	ADJ
fnp-3528	32	73	circuits	circuit	NOUN
fnp-3528	32	74	and	and	CCONJ
fnp-3528	32	75	hampered	hamper	VERB
fnp-3528	32	76	synaptic	synaptic	ADJ
fnp-3528	32	77	communication	communication	NOUN
fnp-3528	32	78	.	.	PUNCT
fnp-3528	33	1	this	this	PRON
fnp-3528	33	2	results	result	VERB
fnp-3528	33	3	in	in	ADP
fnp-3528	33	4	an	an	DET
fnp-3528	33	5	irreversible	irreversible	ADJ
fnp-3528	33	6	atrophy	atrophy	NOUN
fnp-3528	33	7	and	and	CCONJ
fnp-3528	33	8	degeneration	degeneration	NOUN
fnp-3528	33	9	of	of	ADP
fnp-3528	33	10	specific	specific	ADJ
fnp-3528	33	11	brain	brain	NOUN
fnp-3528	33	12	regions	region	NOUN
fnp-3528	33	13	,	,	PUNCT
fnp-3528	33	14	which	which	PRON
fnp-3528	33	15	further	far	ADV
fnp-3528	33	16	causes	cause	VERB
fnp-3528	33	17	behavioral	behavioral	ADJ
fnp-3528	33	18	,	,	PUNCT
fnp-3528	33	19	cognitive	cognitive	ADJ
fnp-3528	33	20	,	,	PUNCT
fnp-3528	33	21	and	and	CCONJ
fnp-3528	33	22	visuospatial	visuospatial	ADJ
fnp-3528	33	23	impairments	impairment	NOUN
fnp-3528	33	24	in	in	ADP
fnp-3528	33	25	the	the	DET
fnp-3528	33	26	progression	progression	NOUN
fnp-3528	33	27	of	of	ADP
fnp-3528	33	28	ad.101	ad.101	PRON
fnp-3528	33	29	the	the	DET
fnp-3528	33	30	most	most	ADV
fnp-3528	33	31	prominent	prominent	ADJ
fnp-3528	33	32	abc	abc	PROPN
fnp-3528	33	33	transporter	transporter	NOUN
fnp-3528	33	34	subfamily	subfamily	ADV
fnp-3528	33	35	involved	involve	VERB
fnp-3528	33	36	in	in	ADP
fnp-3528	33	37	ad	ad	NOUN
fnp-3528	33	38	is	be	AUX
fnp-3528	33	39	the	the	DET
fnp-3528	33	40	abca	abca	NOUN
fnp-3528	33	41	subfamily	subfamily	ADV
fnp-3528	33	42	of	of	ADP
fnp-3528	33	43	cholesterol	cholesterol	NOUN
fnp-3528	33	44	and	and	CCONJ
fnp-3528	33	45	phospholipid	phospholipid	NOUN
fnp-3528	33	46	transporters	transporter	NOUN
fnp-3528	33	47	,	,	PUNCT
fnp-3528	33	48	in	in	ADP
fnp-3528	33	49	which	which	PRON
fnp-3528	33	50	particularly	particularly	ADV
fnp-3528	33	51	abca1	abca1	NOUN
fnp-3528	33	52	,	,	PUNCT
fnp-3528	33	53	abca2	abca2	PROPN
fnp-3528	33	54	,	,	PUNCT
fnp-3528	33	55	abca5	abca5	PROPN
fnp-3528	33	56	,	,	PUNCT
fnp-3528	33	57	and	and	CCONJ
fnp-3528	33	58	abca7	abca7	PROPN
fnp-3528	33	59	have	have	AUX
fnp-3528	33	60	been	be	AUX
fnp-3528	33	61	associated	associate	VERB
fnp-3528	33	62	with	with	ADP
fnp-3528	33	63	ad.28	ad.28	NOUN
fnp-3528	33	64	-	-	PUNCT
fnp-3528	33	65	30,41,43,95,102	30,41,43,95,102	NUM
fnp-3528	33	66	for	for	ADP
fnp-3528	33	67	abca1,28,41,95,103	abca1,28,41,95,103	PROPN
fnp-3528	33	68	and	and	CCONJ
fnp-3528	33	69	specifically	specifically	ADV
fnp-3528	33	70	for	for	ADP
fnp-3528	33	71	abca7,28,41,95,104	abca7,28,41,95,104	PROPN
fnp-3528	33	72	-	-	PUNCT
fnp-3528	33	73	107	107	NUM
fnp-3528	33	74	genetic	genetic	ADJ
fnp-3528	33	75	variant28,41,108	variant28,41,108	NOUN
fnp-3528	33	76	-	-	PUNCT
fnp-3528	33	77	111	111	NUM
fnp-3528	33	78	and	and	CCONJ
fnp-3528	33	79	genome	genome	NOUN
fnp-3528	33	80	-	-	PUNCT
fnp-3528	33	81	wide	wide	ADJ
fnp-3528	33	82	association	association	NOUN
fnp-3528	33	83	studies	study	NOUN
fnp-3528	33	84	(	(	PUNCT
fnp-3528	33	85	gwas)28,41,106,107,112	gwas)28,41,106,107,112	PROPN
fnp-3528	33	86	have	have	AUX
fnp-3528	33	87	suggested	suggest	VERB
fnp-3528	33	88	that	that	SCONJ
fnp-3528	33	89	these	these	DET
fnp-3528	33	90	transporters	transporter	NOUN
fnp-3528	33	91	are	be	AUX
fnp-3528	33	92	risk	risk	NOUN
fnp-3528	33	93	factors	factor	NOUN
fnp-3528	33	94	in	in	ADP
fnp-3528	33	95	ad	ad	NOUN
fnp-3528	33	96	.	.	PUNCT
fnp-3528	34	1	these	these	DET
fnp-3528	34	2	discoveries	discovery	NOUN
fnp-3528	34	3	give	give	VERB
fnp-3528	34	4	the	the	DET
fnp-3528	34	5	members	member	NOUN
fnp-3528	34	6	of	of	ADP
fnp-3528	34	7	the	the	DET
fnp-3528	34	8	abca	abca	NOUN
fnp-3528	34	9	subfamily	subfamily	ADV
fnp-3528	34	10	a	a	DET
fnp-3528	34	11	special	special	ADJ
fnp-3528	34	12	standing	standing	NOUN
fnp-3528	34	13	within	within	ADP
fnp-3528	34	14	the	the	DET
fnp-3528	34	15	group	group	NOUN
fnp-3528	34	16	of	of	ADP
fnp-3528	34	17	ad	ad	NOUN
fnp-3528	34	18	-	-	PUNCT
fnp-3528	34	19	related	relate	VERB
fnp-3528	34	20	abc	abc	NOUN
fnp-3528	34	21	transporters	transporter	NOUN
fnp-3528	34	22	.	.	PUNCT
fnp-3528	35	1	cholesterol	cholesterol	NOUN
fnp-3528	35	2	metabolism	metabolism	NOUN
fnp-3528	35	3	in	in	ADP
fnp-3528	35	4	the	the	DET
fnp-3528	35	5	context	context	NOUN
fnp-3528	35	6	of	of	ADP
fnp-3528	35	7	ad	ad	NOUN
fnp-3528	35	8	has	have	AUX
fnp-3528	35	9	been	be	AUX
fnp-3528	35	10	discussed	discuss	VERB
fnp-3528	35	11	extensively	extensively	ADV
fnp-3528	35	12	before.95,102,104,105,113	before.95,102,104,105,113	ADJ
fnp-3528	35	13	-	-	SYM
fnp-3528	35	14	116	116	NUM
fnp-3528	35	15	the	the	DET
fnp-3528	35	16	contribution	contribution	NOUN
fnp-3528	35	17	of	of	ADP
fnp-3528	35	18	cholesterol	cholesterol	NOUN
fnp-3528	35	19	and	and	CCONJ
fnp-3528	35	20	phosphilipid	phosphilipid	ADJ
fnp-3528	35	21	transport	transport	NOUN
fnp-3528	35	22	to	to	ADP
fnp-3528	35	23	membrane	membrane	NOUN
fnp-3528	35	24	constitution	constitution	NOUN
fnp-3528	35	25	,	,	PUNCT
fnp-3528	35	26	composition	composition	NOUN
fnp-3528	35	27	,	,	PUNCT
fnp-3528	35	28	fluidity	fluidity	NOUN
fnp-3528	35	29	,	,	PUNCT
fnp-3528	35	30	and	and	CCONJ
fnp-3528	35	31	lipid	lipid	NOUN
fnp-3528	35	32	raft	raft	NOUN
fnp-3528	35	33	formation	formation	NOUN
fnp-3528	35	34	mediated	mediate	VERB
fnp-3528	35	35	by	by	ADP
fnp-3528	35	36	abca	abca	NOUN
fnp-3528	35	37	transporters	transporter	NOUN
fnp-3528	35	38	has	have	AUX
fnp-3528	35	39	already	already	ADV
fnp-3528	35	40	been	be	AUX
fnp-3528	35	41	proposed,6	proposed,6	VERB
fnp-3528	35	42	presenting	present	VERB
fnp-3528	35	43	a	a	DET
fnp-3528	35	44	putative	putative	ADJ
fnp-3528	35	45	pharmacological	pharmacological	NOUN
fnp-3528	35	46	target.117	target.117	NOUN
fnp-3528	35	47	targeting	target	VERB
fnp-3528	35	48	cholesterol	cholesterol	NOUN
fnp-3528	35	49	and	and	CCONJ
fnp-3528	35	50	lipid	lipid	NOUN
fnp-3528	35	51	distribution	distribution	NOUN
fnp-3528	35	52	impacts	impact	NOUN
fnp-3528	35	53	aβ	aβ	ADP
fnp-3528	35	54	production	production	NOUN
fnp-3528	35	55	by	by	ADP
fnp-3528	35	56	differential	differential	ADJ
fnp-3528	35	57	activities	activity	NOUN
fnp-3528	35	58	between	between	ADP
fnp-3528	35	59	α-	α-	X
fnp-3528	35	60	,	,	PUNCT
fnp-3528	35	61	β-	β-	X
fnp-3528	35	62	,	,	PUNCT
fnp-3528	35	63	and	and	CCONJ
fnp-3528	35	64	γ	γ	NOUN
fnp-3528	35	65	-	-	PUNCT
fnp-3528	35	66	secretases	secretase	NOUN
fnp-3528	35	67	,	,	PUNCT
fnp-3528	35	68	but	but	CCONJ
fnp-3528	35	69	also	also	ADV
fnp-3528	35	70	amyloid	amyloid	NOUN
fnp-3528	35	71	precursor	precursor	NOUN
fnp-3528	35	72	protein	protein	NOUN
fnp-3528	35	73	(	(	PUNCT
fnp-3528	35	74	app	app	NOUN
fnp-3528	35	75	)	)	PUNCT
fnp-3528	35	76	processing106,118	processing106,118	PROPN
fnp-3528	35	77	-	-	SYM
fnp-3528	35	78	122	122	NUM
fnp-3528	35	79	and	and	CCONJ
fnp-3528	35	80	aβ	aβ	PRON
fnp-3528	35	81	degradation.106,119,123	degradation.106,119,123	PROPN
fnp-3528	35	82	-	-	PUNCT
fnp-3528	35	83	126	126	NUM
fnp-3528	35	84	a	a	DET
fnp-3528	35	85	contribution	contribution	NOUN
fnp-3528	35	86	of	of	ADP
fnp-3528	35	87	abca	abca	NOUN
fnp-3528	35	88	transporters	transporter	NOUN
fnp-3528	35	89	to	to	AUX
fnp-3528	35	90	aβ	aβ	VERB
fnp-3528	35	91	clearance	clearance	NOUN
fnp-3528	35	92	from	from	ADP
fnp-3528	35	93	the	the	DET
fnp-3528	35	94	brain	brain	NOUN
fnp-3528	35	95	was	be	AUX
fnp-3528	35	96	also	also	ADV
fnp-3528	35	97	proposed,103,106,119,124,127	proposed,103,106,119,124,127	ADJ
fnp-3528	35	98	but	but	CCONJ
fnp-3528	35	99	not	not	PART
fnp-3528	35	100	through	through	ADP
fnp-3528	35	101	direct	direct	ADJ
fnp-3528	35	102	aβ	aβ	NOUN
fnp-3528	35	103	transport.128,129	transport.128,129	ADJ
fnp-3528	35	104	although	although	SCONJ
fnp-3528	35	105	abca	abca	NOUN
fnp-3528	35	106	transporters	transporter	NOUN
fnp-3528	35	107	have	have	AUX
fnp-3528	35	108	been	be	AUX
fnp-3528	35	109	reviewed	review	VERB
fnp-3528	35	110	for	for	ADP
fnp-3528	35	111	the	the	DET
fnp-3528	35	112	last	last	ADJ
fnp-3528	35	113	two	two	NUM
fnp-3528	35	114	decades,3,130,131	decades,3,130,131	NOUN
fnp-3528	35	115	little	little	ADJ
fnp-3528	35	116	is	be	AUX
fnp-3528	35	117	known	know	VERB
fnp-3528	35	118	about	about	ADP
fnp-3528	35	119	their	their	PRON
fnp-3528	35	120	specific	specific	ADJ
fnp-3528	35	121	contribution	contribution	NOUN
fnp-3528	35	122	to	to	ADP
fnp-3528	35	123	ad	ad	NOUN
fnp-3528	35	124	pathogenesis	pathogenesis	NOUN
fnp-3528	35	125	and	and	CCONJ
fnp-3528	35	126	their	their	PRON
fnp-3528	35	127	mode	mode	NOUN
fnp-3528	35	128	of	of	ADP
fnp-3528	35	129	action	action	NOUN
fnp-3528	35	130	.	.	PUNCT
fnp-3528	36	1	this	this	PRON
fnp-3528	36	2	is	be	AUX
fnp-3528	36	3	mainly	mainly	ADV
fnp-3528	36	4	due	due	ADJ
fnp-3528	36	5	to	to	ADP
fnp-3528	36	6	a	a	DET
fnp-3528	36	7	lack	lack	NOUN
fnp-3528	36	8	of	of	ADP
fnp-3528	36	9	small	small	ADJ
fnp-3528	36	10	-	-	PUNCT
fnp-3528	36	11	molecules	molecule	NOUN
fnp-3528	36	12	that	that	PRON
fnp-3528	36	13	can	can	AUX
fnp-3528	36	14	be	be	AUX
fnp-3528	36	15	used	use	VERB
fnp-3528	36	16	to	to	PART
fnp-3528	36	17	track	track	VERB
fnp-3528	36	18	,	,	PUNCT
fnp-3528	36	19	study	study	NOUN
fnp-3528	36	20	,	,	PUNCT
fnp-3528	36	21	and	and	CCONJ
fnp-3528	36	22	impact	impact	VERB
fnp-3528	36	23	the	the	DET
fnp-3528	36	24	function	function	NOUN
fnp-3528	36	25	of	of	ADP
fnp-3528	36	26	these	these	DET
fnp-3528	36	27	under	under	ADV
fnp-3528	36	28	-	-	PUNCT
fnp-3528	36	29	studied	study	VERB
fnp-3528	36	30	abc	abc	PROPN
fnp-3528	36	31	transporters	transporter	NOUN
fnp-3528	36	32	.	.	PUNCT
fnp-3528	37	1	the	the	DET
fnp-3528	37	2	present	present	ADJ
fnp-3528	37	3	review	review	NOUN
fnp-3528	37	4	consists	consist	VERB
fnp-3528	37	5	of	of	ADP
fnp-3528	37	6	two	two	NUM
fnp-3528	37	7	parts	part	NOUN
fnp-3528	37	8	:	:	PUNCT
fnp-3528	37	9	part	part	NOUN
fnp-3528	37	10	i	i	PRON
fnp-3528	37	11	provides	provide	VERB
fnp-3528	37	12	the	the	DET
fnp-3528	37	13	status	status	NOUN
fnp-3528	37	14	quo	quo	NOUN
fnp-3528	37	15	of	of	ADP
fnp-3528	37	16	abca	abca	PROPN
fnp-3528	37	17	transporters	transporter	NOUN
fnp-3528	37	18	in	in	ADP
fnp-3528	37	19	ad	ad	NOUN
fnp-3528	37	20	and	and	CCONJ
fnp-3528	37	21	small	small	ADJ
fnp-3528	37	22	-	-	PUNCT
fnp-3528	37	23	molecule	molecule	NOUN
fnp-3528	37	24	modulators	modulator	NOUN
fnp-3528	37	25	–	–	PUNCT
fnp-3528	37	26	in	in	ADP
fnp-3528	37	27	particular	particular	ADJ
fnp-3528	37	28	intrinsic	intrinsic	ADJ
fnp-3528	37	29	substrates	substrate	NOUN
fnp-3528	37	30	,	,	PUNCT
fnp-3528	37	31	natural	natural	ADJ
fnp-3528	37	32	compounds	compound	NOUN
fnp-3528	37	33	,	,	PUNCT
fnp-3528	37	34	pharmacological	pharmacological	ADJ
fnp-3528	37	35	drugs	drug	NOUN
fnp-3528	37	36	,	,	PUNCT
fnp-3528	37	37	and	and	CCONJ
fnp-3528	37	38	synthetic	synthetic	ADJ
fnp-3528	37	39	molecules	molecule	NOUN
fnp-3528	37	40	–	–	PUNCT
fnp-3528	37	41	that	that	PRON
fnp-3528	37	42	have	have	AUX
fnp-3528	37	43	been	be	AUX
fnp-3528	37	44	reported	report	VERB
fnp-3528	37	45	to	to	PART
fnp-3528	37	46	influence	influence	VERB
fnp-3528	37	47	abca	abca	NOUN
fnp-3528	37	48	transporter	transporter	NOUN
fnp-3528	37	49	function	function	NOUN
fnp-3528	37	50	and	and	CCONJ
fnp-3528	37	51	expression	expression	NOUN
fnp-3528	37	52	;	;	PUNCT
fnp-3528	37	53	part	part	NOUN
fnp-3528	37	54	ii	ii	PROPN
fnp-3528	37	55	outlines	outline	VERB
fnp-3528	37	56	the	the	DET
fnp-3528	37	57	necessary	necessary	ADJ
fnp-3528	37	58	drug	drug	NOUN
fnp-3528	37	59	development	development	NOUN
fnp-3528	37	60	pipeline	pipeline	NOUN
fnp-3528	37	61	for	for	ADP
fnp-3528	37	62	the	the	DET
fnp-3528	37	63	discovery	discovery	NOUN
fnp-3528	37	64	of	of	ADP
fnp-3528	37	65	novel	novel	ADJ
fnp-3528	37	66	lead	lead	NOUN
fnp-3528	37	67	structures	structure	NOUN
fnp-3528	37	68	as	as	ADP
fnp-3528	37	69	potential	potential	ADJ
fnp-3528	37	70	innovative	innovative	ADJ
fnp-3528	37	71	diagnostics	diagnostic	NOUN
fnp-3528	37	72	and	and	CCONJ
fnp-3528	37	73	therapeutics	therapeutic	NOUN
fnp-3528	37	74	against	against	ADP
fnp-3528	37	75	ad	ad	NOUN
fnp-3528	37	76	.	.	PUNCT
fnp-3528	38	1	this	this	DET
fnp-3528	38	2	pipeline	pipeline	NOUN
fnp-3528	38	3	includes	include	VERB
fnp-3528	38	4	cutting	cutting	NOUN
fnp-3528	38	5	-	-	PUNCT
fnp-3528	38	6	edge	edge	NOUN
fnp-3528	38	7	in	in	ADP
fnp-3528	38	8	silico	silico	NOUN
fnp-3528	38	9	methodologies	methodology	NOUN
fnp-3528	38	10	,	,	PUNCT
fnp-3528	38	11	established	establish	VERB
fnp-3528	38	12	in	in	ADP
fnp-3528	38	13	vitro	vitro	X
fnp-3528	38	14	cell	cell	NOUN
fnp-3528	38	15	assays	assay	NOUN
fnp-3528	38	16	,	,	PUNCT
fnp-3528	38	17	and	and	CCONJ
fnp-3528	38	18	necessary	necessary	ADJ
fnp-3528	38	19	in	in	ADP
fnp-3528	38	20	vivo	vivo	NOUN
fnp-3528	38	21	models	model	NOUN
fnp-3528	38	22	.	.	PUNCT
fnp-3528	39	1	collectively	collectively	ADV
fnp-3528	39	2	,	,	PUNCT
fnp-3528	39	3	this	this	DET
fnp-3528	39	4	review	review	NOUN
fnp-3528	39	5	contributes	contribute	VERB
fnp-3528	39	6	to	to	ADP
fnp-3528	39	7	a	a	DET
fnp-3528	39	8	deeper	deep	ADJ
fnp-3528	39	9	understanding	understanding	NOUN
fnp-3528	39	10	of	of	ADP
fnp-3528	39	11	small	small	ADJ
fnp-3528	39	12	-	-	PUNCT
fnp-3528	39	13	molecule	molecule	NOUN
fnp-3528	39	14	ligands	ligand	NOUN
fnp-3528	39	15	that	that	PRON
fnp-3528	39	16	influence	influence	VERB
fnp-3528	39	17	abca	abca	NOUN
fnp-3528	39	18	transporter	transporter	NOUN
fnp-3528	39	19	function	function	NOUN
fnp-3528	39	20	,	,	PUNCT
fnp-3528	39	21	potentially	potentially	ADV
fnp-3528	39	22	leading	lead	VERB
fnp-3528	39	23	to	to	ADP
fnp-3528	39	24	the	the	DET
fnp-3528	39	25	development	development	NOUN
fnp-3528	39	26	of	of	ADP
fnp-3528	39	27	novel	novel	ADJ
fnp-3528	39	28	ad	ad	NOUN
fnp-3528	39	29	diagnostics	diagnostic	NOUN
fnp-3528	39	30	and	and	CCONJ
fnp-3528	39	31	therapeutics	therapeutic	NOUN
fnp-3528	39	32	.	.	PUNCT
fnp-3528	40	1	part	part	NOUN
fnp-3528	41	1	i	i	NOUN
fnp-3528	41	2	:	:	PUNCT
fnp-3528	41	3	status	status	NOUN
fnp-3528	41	4	quo	quo	PROPN
fnp-3528	41	5	abca	abca	NOUN
fnp-3528	41	6	transporters	transporter	NOUN
fnp-3528	41	7	:	:	PUNCT
fnp-3528	41	8	physiological	physiological	ADJ
fnp-3528	41	9	function	function	NOUN
fnp-3528	41	10	and	and	CCONJ
fnp-3528	41	11	implications	implication	NOUN
fnp-3528	41	12	for	for	ADP
fnp-3528	41	13	ad	ad	NOUN
fnp-3528	41	14	abca	abca	NOUN
fnp-3528	41	15	transporters	transporter	NOUN
fnp-3528	41	16	are	be	AUX
fnp-3528	41	17	ubiquitously	ubiquitously	ADV
fnp-3528	41	18	present	present	ADJ
fnp-3528	41	19	in	in	ADP
fnp-3528	41	20	the	the	DET
fnp-3528	41	21	human	human	NOUN
fnp-3528	41	22	body,3,10,13	body,3,10,13	PROPN
fnp-3528	41	23	although	although	SCONJ
fnp-3528	41	24	differentially	differentially	ADV
fnp-3528	41	25	expressed.10	expressed.10	VERB
fnp-3528	41	26	all	all	PRON
fnp-3528	41	27	of	of	ADP
fnp-3528	41	28	the	the	DET
fnp-3528	41	29	12	12	NUM
fnp-3528	41	30	subfamily	subfamily	NOUN
fnp-3528	41	31	members	member	NOUN
fnp-3528	41	32	have	have	AUX
fnp-3528	41	33	been	be	AUX
fnp-3528	41	34	associated	associate	VERB
fnp-3528	41	35	with	with	ADP
fnp-3528	41	36	cholesterol	cholesterol	NOUN
fnp-3528	41	37	and/or	and/or	CCONJ
fnp-3528	41	38	phospholipid	phospholipid	NOUN
fnp-3528	41	39	transport	transport	NOUN
fnp-3528	41	40	and	and	CCONJ
fnp-3528	41	41	homeostasis,3,13,132	homeostasis,3,13,132	PUNCT
fnp-3528	41	42	except	except	SCONJ
fnp-3528	41	43	for	for	ADP
fnp-3528	41	44	abca4	abca4	PROPN
fnp-3528	41	45	,	,	PUNCT
fnp-3528	41	46	which	which	PRON
fnp-3528	41	47	is	be	AUX
fnp-3528	41	48	primarily	primarily	ADV
fnp-3528	41	49	a	a	DET
fnp-3528	41	50	transporter	transporter	NOUN
fnp-3528	41	51	of	of	ADP
fnp-3528	41	52	retinoids.133	retinoids.133	NUM
fnp-3528	41	53	-	-	PUNCT
fnp-3528	41	54	138	138	NUM
fnp-3528	41	55	in	in	ADP
fnp-3528	41	56	addition	addition	NOUN
fnp-3528	41	57	to	to	ADP
fnp-3528	41	58	the	the	DET
fnp-3528	41	59	diseases	disease	NOUN
fnp-3528	41	60	listed	list	VERB
fnp-3528	41	61	in	in	ADP
fnp-3528	41	62	table	table	NOUN
fnp-3528	41	63	 	 	SPACE
fnp-3528	41	64	1	1	NUM
fnp-3528	41	65	,	,	PUNCT
fnp-3528	41	66	abca	abca	NOUN
fnp-3528	41	67	transporters	transporter	NOUN
fnp-3528	41	68	have	have	AUX
fnp-3528	41	69	been	be	AUX
fnp-3528	41	70	described	describe	VERB
fnp-3528	41	71	as	as	ADP
fnp-3528	41	72	key	key	ADJ
fnp-3528	41	73	proteins	protein	NOUN
fnp-3528	41	74	in	in	ADP
fnp-3528	41	75	several	several	ADJ
fnp-3528	41	76	other	other	ADJ
fnp-3528	41	77	human	human	ADJ
fnp-3528	41	78	disorders	disorder	NOUN
fnp-3528	41	79	,	,	PUNCT
fnp-3528	41	80	including	include	VERB
fnp-3528	41	81	neonatal	neonatal	ADJ
fnp-3528	41	82	respiratory	respiratory	ADJ
fnp-3528	41	83	distress	distress	NOUN
fnp-3528	41	84	syndrome	syndrome	NOUN
fnp-3528	41	85	(	(	PUNCT
fnp-3528	41	86	abca3),139	abca3),139	ADP
fnp-3528	41	87	chronic	chronic	ADJ
fnp-3528	41	88	interstitial	interstitial	ADJ
fnp-3528	41	89	lung	lung	NOUN
fnp-3528	41	90	disease	disease	NOUN
fnp-3528	41	91	(	(	PUNCT
fnp-3528	41	92	abca3),140	abca3),140	ADJ
fnp-3528	41	93	cataract	cataract	NOUN
fnp-3528	41	94	-	-	PUNCT
fnp-3528	41	95	microcornea	microcornea	NOUN
fnp-3528	41	96	syndrome	syndrome	NOUN
fnp-3528	41	97	(	(	PUNCT
fnp-3528	41	98	abca3),141	abca3),141	NOUN
fnp-3528	41	99	hypertrichosis	hypertrichosis	NOUN
fnp-3528	41	100	terminalis	terminali	NOUN
fnp-3528	41	101	(	(	PUNCT
fnp-3528	41	102	abca5),142	abca5),142	PROPN
fnp-3528	41	103	or	or	CCONJ
fnp-3528	41	104	harlequin	harlequin	PROPN
fnp-3528	41	105	ichtyosis	ichtyosis	NOUN
fnp-3528	41	106	(	(	PUNCT
fnp-3528	41	107	abca12).143	abca12).143	NOUN
fnp-3528	41	108	however	however	ADV
fnp-3528	41	109	,	,	PUNCT
fnp-3528	41	110	one	one	NUM
fnp-3528	41	111	major	major	ADJ
fnp-3528	41	112	clinical	clinical	ADJ
fnp-3528	41	113	implication	implication	NOUN
fnp-3528	41	114	for	for	ADP
fnp-3528	41	115	abca	abca	PROPN
fnp-3528	41	116	transporters	transporter	NOUN
fnp-3528	41	117	,	,	PUNCT
fnp-3528	41	118	particularly	particularly	ADV
fnp-3528	41	119	abca1	abca1	NOUN
fnp-3528	41	120	,	,	PUNCT
fnp-3528	41	121	abca2	abca2	PROPN
fnp-3528	41	122	,	,	PUNCT
fnp-3528	41	123	abca5	abca5	PROPN
fnp-3528	41	124	,	,	PUNCT
fnp-3528	41	125	and	and	CCONJ
fnp-3528	41	126	abca7	abca7	PROPN
fnp-3528	41	127	,	,	PUNCT
fnp-3528	41	128	relates	relate	VERB
fnp-3528	41	129	to	to	ADP
fnp-3528	41	130	ad.28,50,52,63	ad.28,50,52,63	PROPN
fnp-3528	41	131	their	their	PRON
fnp-3528	41	132	suggested	suggest	VERB
fnp-3528	41	133	roles	role	NOUN
fnp-3528	41	134	in	in	ADP
fnp-3528	41	135	this	this	DET
fnp-3528	41	136	major	major	ADJ
fnp-3528	41	137	burdensome	burdensome	ADJ
fnp-3528	41	138	neurodegenerative	neurodegenerative	ADJ
fnp-3528	41	139	disease	disease	NOUN
fnp-3528	41	140	as	as	ADV
fnp-3528	41	141	well	well	ADV
fnp-3528	41	142	as	as	ADP
fnp-3528	41	143	general	general	ADJ
fnp-3528	41	144	physiological	physiological	ADJ
fnp-3528	41	145	aspects	aspect	NOUN
fnp-3528	41	146	are	be	AUX
fnp-3528	41	147	summarized	summarize	VERB
fnp-3528	41	148	in	in	ADP
fnp-3528	41	149	the	the	DET
fnp-3528	41	150	following	follow	VERB
fnp-3528	41	151	sections	section	NOUN
fnp-3528	41	152	.	.	PUNCT
fnp-3528	42	1	abca1	abca1	NOUN
fnp-3528	42	2	abca1	abca1	NOUN
fnp-3528	42	3	is	be	AUX
fnp-3528	42	4	the	the	DET
fnp-3528	42	5	prototype	prototype	NOUN
fnp-3528	42	6	of	of	ADP
fnp-3528	42	7	the	the	DET
fnp-3528	42	8	abca	abca	PROPN
fnp-3528	42	9	subfamily,144	subfamily,144	PROPN
fnp-3528	42	10	was	be	AUX
fnp-3528	42	11	first	first	ADV
fnp-3528	42	12	identified	identify	VERB
fnp-3528	42	13	in	in	ADP
fnp-3528	42	14	1994	1994	NUM
fnp-3528	42	15	,	,	PUNCT
fnp-3528	42	16	and	and	CCONJ
fnp-3528	42	17	is	be	AUX
fnp-3528	42	18	located	locate	VERB
fnp-3528	42	19	on	on	ADP
fnp-3528	42	20	human	human	ADJ
fnp-3528	42	21	chromosome	chromosome	NOUN
fnp-3528	42	22	9.145	9.145	NUM
fnp-3528	42	23	the	the	DET
fnp-3528	42	24	complete	complete	ADJ
fnp-3528	42	25	genomic	genomic	ADJ
fnp-3528	42	26	sequence	sequence	NOUN
fnp-3528	42	27	of	of	ADP
fnp-3528	42	28	human	human	ADJ
fnp-3528	42	29	abca1	abca1	NOUN
fnp-3528	42	30	was	be	AUX
fnp-3528	42	31	reported	report	VERB
fnp-3528	42	32	in	in	ADP
fnp-3528	42	33	2000	2000	NUM
fnp-3528	42	34	.	.	PUNCT
fnp-3528	43	1	the	the	DET
fnp-3528	43	2	abca1	abca1	NOUN
fnp-3528	43	3	gene	gene	NOUN
fnp-3528	43	4	spans	span	VERB
fnp-3528	43	5	149	149	NUM
fnp-3528	43	6	kb	kb	NOUN
fnp-3528	43	7	comprising	comprise	VERB
fnp-3528	43	8	50	50	NUM
fnp-3528	43	9	exons	exon	NOUN
fnp-3528	43	10	,	,	PUNCT
fnp-3528	43	11	and	and	CCONJ
fnp-3528	43	12	the	the	DET
fnp-3528	43	13	resulting	result	VERB
fnp-3528	43	14	protein	protein	NOUN
fnp-3528	43	15	is	be	AUX
fnp-3528	43	16	2261	2261	NUM
fnp-3528	43	17	amino	amino	NOUN
fnp-3528	43	18	acids	acid	NOUN
fnp-3528	43	19	long.146	long.146	PROPN
fnp-3528	43	20	abca1	abca1	NOUN
fnp-3528	43	21	is	be	AUX
fnp-3528	43	22	located	locate	VERB
fnp-3528	43	23	in	in	ADP
fnp-3528	43	24	the	the	DET
fnp-3528	43	25	plasma	plasma	NOUN
fnp-3528	43	26	membrane	membrane	NOUN
fnp-3528	43	27	and	and	CCONJ
fnp-3528	43	28	is	be	AUX
fnp-3528	43	29	also	also	ADV
fnp-3528	43	30	present	present	ADJ
fnp-3528	43	31	intracellularly	intracellularly	ADV
fnp-3528	43	32	in	in	ADP
fnp-3528	43	33	the	the	DET
fnp-3528	43	34	endoplasmic	endoplasmic	ADJ
fnp-3528	43	35	reticulum	reticulum	NOUN
fnp-3528	43	36	and	and	CCONJ
fnp-3528	43	37	golgi	golgi	NOUN
fnp-3528	43	38	apparatus	apparatus	NOUN
fnp-3528	43	39	,	,	PUNCT
fnp-3528	43	40	where	where	SCONJ
fnp-3528	43	41	it	it	PRON
fnp-3528	43	42	mediates	mediate	VERB
fnp-3528	43	43	the	the	DET
fnp-3528	43	44	efflux	efflux	NOUN
fnp-3528	43	45	of	of	ADP
fnp-3528	43	46	cholesterol	cholesterol	NOUN
fnp-3528	43	47	and	and	CCONJ
fnp-3528	43	48	phospholipids	phospholipid	NOUN
fnp-3528	43	49	from	from	ADP
fnp-3528	43	50	intracellular	intracellular	ADJ
fnp-3528	43	51	compartments	compartment	NOUN
fnp-3528	43	52	to	to	ADP
fnp-3528	43	53	extracellular	extracellular	ADJ
fnp-3528	43	54	lipid	lipid	NOUN
fnp-3528	43	55	-	-	PUNCT
fnp-3528	43	56	free	free	ADJ
fnp-3528	43	57	apolipoproteins	apolipoprotein	NOUN
fnp-3528	43	58	,	,	PUNCT
fnp-3528	43	59	mainly	mainly	ADV
fnp-3528	43	60	apolipoprotein	apolipoprotein	ADJ
fnp-3528	43	61	a1	a1	NOUN
fnp-3528	43	62	(	(	PUNCT
fnp-3528	43	63	apoa1	apoa1	ADJ
fnp-3528	43	64	)	)	PUNCT
fnp-3528	43	65	and	and	CCONJ
fnp-3528	43	66	to	to	ADP
fnp-3528	43	67	a	a	DET
fnp-3528	43	68	lesser	less	ADJ
fnp-3528	43	69	extend	extend	NOUN
fnp-3528	43	70	apoa2	apoa2	NOUN
fnp-3528	43	71	and	and	CCONJ
fnp-3528	43	72	apoe	apoe	NOUN
fnp-3528	43	73	,	,	PUNCT
fnp-3528	43	74	to	to	PART
fnp-3528	43	75	form	form	VERB
fnp-3528	43	76	high	high	ADJ
fnp-3528	43	77	-	-	PUNCT
fnp-3528	43	78	density	density	NOUN
fnp-3528	43	79	lipoprotein	lipoprotein	ADJ
fnp-3528	43	80	(	(	PUNCT
fnp-3528	43	81	hdl	hdl	NOUN
fnp-3528	43	82	)	)	PUNCT
fnp-3528	43	83	particles.3,147,148	particles.3,147,148	NOUN
fnp-3528	43	84	the	the	DET
fnp-3528	43	85	lipidation	lipidation	NOUN
fnp-3528	43	86	of	of	ADP
fnp-3528	43	87	apoa1	apoa1	PROPN
fnp-3528	43	88	is	be	AUX
fnp-3528	43	89	preceded	precede	VERB
fnp-3528	43	90	by	by	ADP
fnp-3528	43	91	abca1	abca1	NOUN
fnp-3528	43	92	dimerization.149	dimerization.149	NOUN
fnp-3528	43	93	abca1	abca1	NOUN
fnp-3528	43	94	thus	thus	ADV
fnp-3528	43	95	represents	represent	VERB
fnp-3528	43	96	the	the	DET
fnp-3528	43	97	first	first	ADJ
fnp-3528	43	98	and	and	CCONJ
fnp-3528	43	99	rate	rate	NOUN
fnp-3528	43	100	-	-	PUNCT
fnp-3528	43	101	limiting	limit	VERB
fnp-3528	43	102	step	step	NOUN
fnp-3528	43	103	in	in	ADP
fnp-3528	43	104	the	the	DET
fnp-3528	43	105	reverse	reverse	ADJ
fnp-3528	43	106	cholesterol	cholesterol	NOUN
fnp-3528	43	107	transport	transport	NOUN
fnp-3528	43	108	pathway	pathway	NOUN
fnp-3528	43	109	,	,	PUNCT
fnp-3528	43	110	which	which	PRON
fnp-3528	43	111	removes	remove	VERB
fnp-3528	43	112	excess	excess	ADJ
fnp-3528	43	113	cholesterol	cholesterol	NOUN
fnp-3528	43	114	from	from	ADP
fnp-3528	43	115	peripheral	peripheral	ADJ
fnp-3528	43	116	tissues	tissue	NOUN
fnp-3528	43	117	via	via	ADP
fnp-3528	43	118	hdl	hdl	PROPN
fnp-3528	43	119	and	and	CCONJ
fnp-3528	43	120	delivers	deliver	VERB
fnp-3528	43	121	it	it	PRON
fnp-3528	43	122	to	to	ADP
fnp-3528	43	123	the	the	DET
fnp-3528	43	124	liver	liver	NOUN
fnp-3528	43	125	for	for	ADP
fnp-3528	43	126	conversion	conversion	NOUN
fnp-3528	43	127	into	into	ADP
fnp-3528	43	128	bile	bile	NOUN
fnp-3528	43	129	acids	acid	NOUN
fnp-3528	43	130	and	and	CCONJ
fnp-3528	43	131	subsequent	subsequent	ADJ
fnp-3528	43	132	excretion	excretion	NOUN
fnp-3528	43	133	.	.	PUNCT
fnp-3528	44	1	in	in	ADP
fnp-3528	44	2	contrast	contrast	NOUN
fnp-3528	44	3	to	to	ADP
fnp-3528	44	4	peripheral	peripheral	ADJ
fnp-3528	44	5	tissues	tissue	NOUN
fnp-3528	44	6	,	,	PUNCT
fnp-3528	44	7	the	the	DET
fnp-3528	44	8	physiological	physiological	ADJ
fnp-3528	44	9	role	role	NOUN
fnp-3528	44	10	of	of	ADP
fnp-3528	44	11	abca1	abca1	NOUN
fnp-3528	44	12	in	in	ADP
fnp-3528	44	13	the	the	DET
fnp-3528	44	14	brain	brain	NOUN
fnp-3528	44	15	,	,	PUNCT
fnp-3528	44	16	where	where	SCONJ
fnp-3528	44	17	it	it	PRON
fnp-3528	44	18	is	be	AUX
fnp-3528	44	19	expressed	express	VERB
fnp-3528	44	20	in	in	ADP
fnp-3528	44	21	all	all	DET
fnp-3528	44	22	cell	cell	NOUN
fnp-3528	44	23	types	type	NOUN
fnp-3528	44	24	,	,	PUNCT
fnp-3528	44	25	is	be	AUX
fnp-3528	44	26	not	not	PART
fnp-3528	44	27	well	well	ADV
fnp-3528	44	28	defined.103	defined.103	VERB
fnp-3528	44	29	it	it	PRON
fnp-3528	44	30	has	have	AUX
fnp-3528	44	31	been	be	AUX
fnp-3528	44	32	suggested	suggest	VERB
fnp-3528	44	33	that	that	SCONJ
fnp-3528	44	34	abca1	abca1	NOUN
fnp-3528	44	35	is	be	AUX
fnp-3528	44	36	required	require	VERB
fnp-3528	44	37	for	for	ADP
fnp-3528	44	38	cholesterol	cholesterol	NOUN
fnp-3528	44	39	transport	transport	NOUN
fnp-3528	44	40	from	from	ADP
fnp-3528	44	41	glial	glial	ADJ
fnp-3528	44	42	cells	cell	NOUN
fnp-3528	44	43	to	to	ADP
fnp-3528	44	44	neurons	neuron	NOUN
fnp-3528	44	45	via	via	ADP
fnp-3528	44	46	apoe	apoe	NOUN
fnp-3528	44	47	,	,	PUNCT
fnp-3528	44	48	which	which	PRON
fnp-3528	44	49	is	be	AUX
fnp-3528	44	50	secreted	secrete	VERB
fnp-3528	44	51	by	by	ADP
fnp-3528	44	52	glial	glial	ADJ
fnp-3528	44	53	cells	cell	NOUN
fnp-3528	44	54	and	and	CCONJ
fnp-3528	44	55	serves	serve	VERB
fnp-3528	44	56	as	as	ADP
fnp-3528	44	57	the	the	DET
fnp-3528	44	58	main	main	ADJ
fnp-3528	44	59	lipid	lipid	NOUN
fnp-3528	44	60	acceptor	acceptor	NOUN
fnp-3528	44	61	in	in	ADP
fnp-3528	44	62	the	the	DET
fnp-3528	44	63	brain.103,125	brain.103,125	NOUN
fnp-3528	44	64	in	in	ADP
fnp-3528	44	65	vitro	vitro	X
fnp-3528	44	66	and	and	CCONJ
fnp-3528	44	67	in	in	ADP
fnp-3528	44	68	vivo	vivo	ADJ
fnp-3528	44	69	studies	study	NOUN
fnp-3528	44	70	in	in	ADP
fnp-3528	44	71	abca1	abca1	NOUN
fnp-3528	44	72	knock	knock	VERB
fnp-3528	44	73	-	-	PUNCT
fnp-3528	44	74	out	out	ADP
fnp-3528	44	75	models	model	NOUN
fnp-3528	44	76	demonstrated	demonstrate	VERB
fnp-3528	44	77	that	that	SCONJ
fnp-3528	44	78	abca1	abca1	NOUN
fnp-3528	44	79	is	be	AUX
fnp-3528	44	80	essential	essential	ADJ
fnp-3528	44	81	for	for	ADP
fnp-3528	44	82	normal	normal	ADJ
fnp-3528	44	83	apoe	apoe	ADJ
fnp-3528	44	84	secretion	secretion	NOUN
fnp-3528	44	85	and	and	CCONJ
fnp-3528	44	86	lipidation	lipidation	NOUN
fnp-3528	44	87	in	in	ADP
fnp-3528	44	88	the	the	DET
fnp-3528	44	89	cns.150,151	cns.150,151	NOUN
fnp-3528	44	90	glial	glial	ADJ
fnp-3528	44	91	cells	cell	NOUN
fnp-3528	44	92	deficient	deficient	ADJ
fnp-3528	44	93	for	for	ADP
fnp-3528	44	94	abca1	abca1	NOUN
fnp-3528	44	95	showed	show	VERB
fnp-3528	44	96	reduced	reduce	VERB
fnp-3528	44	97	lipid	lipid	NOUN
fnp-3528	44	98	efflux	efflux	VERB
fnp-3528	44	99	with	with	ADP
fnp-3528	44	100	concurrent	concurrent	ADJ
fnp-3528	44	101	lipid	lipid	NOUN
fnp-3528	44	102	accumulation	accumulation	NOUN
fnp-3528	44	103	as	as	ADV
fnp-3528	44	104	well	well	ADV
fnp-3528	44	105	as	as	ADP
fnp-3528	44	106	decreased	decrease	VERB
fnp-3528	44	107	apoe	apoe	ADJ
fnp-3528	44	108	secretion	secretion	NOUN
fnp-3528	44	109	,	,	PUNCT
fnp-3528	44	110	with	with	ADP
fnp-3528	44	111	apoe	apoe	ADJ
fnp-3528	44	112	particles	particle	NOUN
fnp-3528	44	113	being	be	AUX
fnp-3528	44	114	small	small	ADJ
fnp-3528	44	115	and	and	CCONJ
fnp-3528	44	116	poorly	poorly	ADV
fnp-3528	44	117	lipidated	lipidate	VERB
fnp-3528	44	118	.	.	PUNCT
fnp-3528	45	1	in	in	ADP
fnp-3528	45	2	mice	mouse	NOUN
fnp-3528	45	3	,	,	PUNCT
fnp-3528	45	4	abca1	abca1	NOUN
fnp-3528	45	5	knock	knock	NOUN
fnp-3528	45	6	-	-	PUNCT
fnp-3528	45	7	out	out	NOUN
fnp-3528	45	8	resulted	result	VERB
fnp-3528	45	9	in	in	ADP
fnp-3528	45	10	dramatically	dramatically	ADV
fnp-3528	45	11	decreased	decrease	VERB
fnp-3528	45	12	brain	brain	NOUN
fnp-3528	45	13	levels	level	NOUN
fnp-3528	45	14	of	of	ADP
fnp-3528	45	15	apoe	apoe	NOUN
fnp-3528	45	16	.	.	PUNCT
fnp-3528	46	1	moreover	moreover	ADV
fnp-3528	46	2	,	,	PUNCT
fnp-3528	46	3	examination	examination	NOUN
fnp-3528	46	4	of	of	ADP
fnp-3528	46	5	the	the	DET
fnp-3528	46	6	hippocampi	hippocampi	ADJ
fnp-3528	46	7	of	of	ADP
fnp-3528	46	8	abca1	abca1	NOUN
fnp-3528	46	9	-	-	PUNCT
fnp-3528	46	10	deficient	deficient	ADJ
fnp-3528	46	11	mice	mouse	NOUN
fnp-3528	46	12	revealed	reveal	VERB
fnp-3528	46	13	a	a	DET
fnp-3528	46	14	decrease	decrease	NOUN
fnp-3528	46	15	in	in	ADP
fnp-3528	46	16	neurite	neurite	ADJ
fnp-3528	46	17	length	length	NOUN
fnp-3528	46	18	and	and	CCONJ
fnp-3528	46	19	number	number	NOUN
fnp-3528	46	20	of	of	ADP
fnp-3528	46	21	neurite	neurite	ADJ
fnp-3528	46	22	segments	segment	NOUN
fnp-3528	46	23	and	and	CCONJ
fnp-3528	46	24	branches	branch	NOUN
fnp-3528	46	25	,	,	PUNCT
fnp-3528	46	26	pointing	point	VERB
fnp-3528	46	27	to	to	ADP
fnp-3528	46	28	an	an	DET
fnp-3528	46	29	importance	importance	NOUN
fnp-3528	46	30	of	of	ADP
fnp-3528	46	31	abca1	abca1	NOUN
fnp-3528	46	32	for	for	ADP
fnp-3528	46	33	neurite	neurite	NOUN
fnp-3528	46	34	integrity.152	integrity.152	NOUN
fnp-3528	46	35	the	the	DET
fnp-3528	46	36	major	major	ADJ
fnp-3528	46	37	genetic	genetic	ADJ
fnp-3528	46	38	risk	risk	NOUN
fnp-3528	46	39	factor	factor	NOUN
fnp-3528	46	40	for	for	ADP
fnp-3528	46	41	sporadic	sporadic	ADJ
fnp-3528	46	42	ad	ad	NOUN
fnp-3528	46	43	is	be	AUX
fnp-3528	46	44	the	the	DET
fnp-3528	46	45	allelic	allelic	ADJ
fnp-3528	46	46	state	state	NOUN
fnp-3528	46	47	of	of	ADP
fnp-3528	46	48	the	the	DET
fnp-3528	46	49	apoe	apoe	ADJ
fnp-3528	46	50	genotype	genotype	NOUN
fnp-3528	46	51	,	,	PUNCT
fnp-3528	46	52	with	with	SCONJ
fnp-3528	46	53	inheritance	inheritance	NOUN
fnp-3528	46	54	of	of	ADP
fnp-3528	46	55	the	the	DET
fnp-3528	46	56	apoe4	apoe4	PROPN
fnp-3528	46	57	allele	allele	NOUN
fnp-3528	46	58	markedly	markedly	ADV
fnp-3528	46	59	increasing	increase	VERB
fnp-3528	46	60	disease	disease	NOUN
fnp-3528	46	61	risk.153,154	risk.153,154	VERB
fnp-3528	46	62	recently	recently	ADV
fnp-3528	46	63	,	,	PUNCT
fnp-3528	47	1	rawat	rawat	PROPN
fnp-3528	47	2	et	et	PROPN
fnp-3528	47	3	al	al	PROPN
fnp-3528	47	4	.	.	PROPN
fnp-3528	47	5	investigated	investigate	VERB
fnp-3528	47	6	how	how	SCONJ
fnp-3528	47	7	apoe4	apoe4	ADJ
fnp-3528	47	8	affected	affected	ADJ
fnp-3528	47	9	abca1	abca1	NOUN
fnp-3528	47	10	expression	expression	NOUN
fnp-3528	47	11	and	and	CCONJ
fnp-3528	47	12	function	function	NOUN
fnp-3528	47	13	in	in	ADP
fnp-3528	47	14	vitro	vitro	X
fnp-3528	47	15	in	in	ADP
fnp-3528	47	16	astrocytes.155	astrocytes.155	NOUN
fnp-3528	47	17	the	the	DET
fnp-3528	47	18	authors	author	NOUN
fnp-3528	47	19	found	find	VERB
fnp-3528	47	20	that	that	SCONJ
fnp-3528	47	21	apoe4	apoe4	PROPN
fnp-3528	47	22	decreased	decrease	VERB
fnp-3528	47	23	abca1	abca1	NOUN
fnp-3528	47	24	plasma	plasma	NOUN
fnp-3528	47	25	membrane	membrane	NOUN
fnp-3528	47	26	levels	level	NOUN
fnp-3528	47	27	and	and	CCONJ
fnp-3528	47	28	increased	increase	VERB
fnp-3528	47	29	abca1	abca1	NOUN
fnp-3528	47	30	co	co	NOUN
fnp-3528	47	31	-	-	NOUN
fnp-3528	47	32	localization	localization	NOUN
fnp-3528	47	33	with	with	ADP
fnp-3528	47	34	late	late	ADJ
fnp-3528	47	35	endosomes	endosome	NOUN
fnp-3528	47	36	via	via	ADP
fnp-3528	47	37	activation	activation	NOUN
fnp-3528	47	38	of	of	ADP
fnp-3528	47	39	adp	adp	PROPN
fnp-3528	47	40	-	-	PUNCT
fnp-3528	47	41	ribosylation	ribosylation	NOUN
fnp-3528	47	42	factor	factor	NOUN
fnp-3528	47	43	6	6	NUM
fnp-3528	47	44	,	,	PUNCT
fnp-3528	47	45	thereby	thereby	ADV
fnp-3528	47	46	reducing	reduce	VERB
fnp-3528	47	47	cholesterol	cholesterol	NOUN
fnp-3528	47	48	efflux	efflux	NOUN
fnp-3528	47	49	and	and	CCONJ
fnp-3528	47	50	lipidation	lipidation	NOUN
fnp-3528	47	51	of	of	ADP
fnp-3528	47	52	apoe	apoe	ADJ
fnp-3528	47	53	particles	particle	NOUN
fnp-3528	47	54	.	.	PUNCT
fnp-3528	48	1	they	they	PRON
fnp-3528	48	2	corroborated	corroborate	VERB
fnp-3528	48	3	their	their	PRON
fnp-3528	48	4	findings	finding	NOUN
fnp-3528	48	5	in	in	ADP
fnp-3528	48	6	blood	blood	NOUN
fnp-3528	48	7	-	-	PUNCT
fnp-3528	48	8	cerebrospinal	cerebrospinal	ADJ
fnp-3528	48	9	fluid	fluid	NOUN
fnp-3528	48	10	(	(	PUNCT
fnp-3528	48	11	csf	csf	NOUN
fnp-3528	48	12	)	)	PUNCT
fnp-3528	48	13	showing	show	VERB
fnp-3528	48	14	that	that	PRON
fnp-3528	48	15	csf	csf	NOUN
fnp-3528	48	16	from	from	ADP
fnp-3528	48	17	homozygous	homozygous	ADJ
fnp-3528	48	18	carriers	carrier	NOUN
fnp-3528	48	19	of	of	ADP
fnp-3528	48	20	the	the	DET
fnp-3528	48	21	apoe4	apoe4	PROPN
fnp-3528	48	22	allele	allele	NOUN
fnp-3528	48	23	was	be	AUX
fnp-3528	48	24	less	less	ADV
fnp-3528	48	25	efficient	efficient	ADJ
fnp-3528	48	26	in	in	ADP
fnp-3528	48	27	stimulating	stimulate	VERB
fnp-3528	48	28	abca1	abca1	NOUN
fnp-3528	48	29	-	-	PUNCT
fnp-3528	48	30	mediated	mediate	VERB
fnp-3528	48	31	cholesterol	cholesterol	NOUN
fnp-3528	48	32	efflux	efflux	NOUN
fnp-3528	48	33	compared	compare	VERB
fnp-3528	48	34	to	to	ADP
fnp-3528	48	35	csf	csf	VERB
fnp-3528	48	36	from	from	ADP
fnp-3528	48	37	homozygous	homozygous	ADJ
fnp-3528	48	38	carriers	carrier	NOUN
fnp-3528	48	39	of	of	ADP
fnp-3528	48	40	the	the	DET
fnp-3528	48	41	apoe3	apoe3	PROPN
fnp-3528	48	42	allele	allele	PROPN
fnp-3528	48	43	.	.	PUNCT
fnp-3528	49	1	a	a	DET
fnp-3528	49	2	recent	recent	ADJ
fnp-3528	49	3	study	study	NOUN
fnp-3528	49	4	assessed	assess	VERB
fnp-3528	49	5	cholesterol	cholesterol	NOUN
fnp-3528	49	6	efflux	efflux	NOUN
fnp-3528	49	7	capacity	capacity	NOUN
fnp-3528	49	8	of	of	ADP
fnp-3528	49	9	csf	csf	NOUN
fnp-3528	49	10	by	by	ADP
fnp-3528	49	11	analyzing	analyze	VERB
fnp-3528	49	12	ad	ad	NOUN
fnp-3528	49	13	patients	patient	NOUN
fnp-3528	49	14	,	,	PUNCT
fnp-3528	49	15	non	non	ADJ
fnp-3528	49	16	-	-	ADJ
fnp-3528	49	17	ad	ad	ADJ
fnp-3528	49	18	patients	patient	NOUN
fnp-3528	49	19	,	,	PUNCT
fnp-3528	49	20	and	and	CCONJ
fnp-3528	49	21	control	control	VERB
fnp-3528	49	22	subjects.156	subjects.156	PROPN
fnp-3528	49	23	the	the	DET
fnp-3528	49	24	results	result	NOUN
fnp-3528	49	25	demonstrated	demonstrate	VERB
fnp-3528	49	26	that	that	SCONJ
fnp-3528	49	27	abca1	abca1	NOUN
fnp-3528	49	28	-	-	PUNCT
fnp-3528	49	29	mediated	mediate	VERB
fnp-3528	49	30	csf	csf	ADJ
fnp-3528	49	31	-	-	PUNCT
fnp-3528	49	32	cholesterol	cholesterol	NOUN
fnp-3528	49	33	efflux	efflux	NOUN
fnp-3528	49	34	capacity	capacity	NOUN
fnp-3528	49	35	was	be	AUX
fnp-3528	49	36	markedly	markedly	ADV
fnp-3528	49	37	reduced	reduce	VERB
fnp-3528	49	38	in	in	ADP
fnp-3528	49	39	ad	ad	NOUN
fnp-3528	49	40	but	but	CCONJ
fnp-3528	49	41	not	not	PART
fnp-3528	49	42	in	in	ADP
fnp-3528	49	43	non	non	ADJ
fnp-3528	49	44	-	-	ADJ
fnp-3528	49	45	ad	ad	ADJ
fnp-3528	49	46	demented	demented	ADJ
fnp-3528	49	47	patients	patient	NOUN
fnp-3528	49	48	.	.	PUNCT
fnp-3528	50	1	however	however	ADV
fnp-3528	50	2	,	,	PUNCT
fnp-3528	50	3	this	this	DET
fnp-3528	50	4	difference	difference	NOUN
fnp-3528	50	5	did	do	AUX
fnp-3528	50	6	not	not	PART
fnp-3528	50	7	depend	depend	VERB
fnp-3528	50	8	on	on	ADP
fnp-3528	50	9	apoe4	apoe4	PROPN
fnp-3528	50	10	status	status	NOUN
fnp-3528	50	11	.	.	PUNCT
fnp-3528	51	1	interestingly	interestingly	ADV
fnp-3528	51	2	,	,	PUNCT
fnp-3528	51	3	abca1	abca1	NOUN
fnp-3528	51	4	-	-	PUNCT
fnp-3528	51	5	mediated	mediate	VERB
fnp-3528	51	6	csf	csf	ADJ
fnp-3528	51	7	-	-	PUNCT
fnp-3528	51	8	cholesterol	cholesterol	NOUN
fnp-3528	51	9	efflux	efflux	NOUN
fnp-3528	51	10	capacity	capacity	NOUN
fnp-3528	51	11	inversely	inversely	ADV
fnp-3528	51	12	correlated	correlate	VERB
fnp-3528	51	13	with	with	ADP
fnp-3528	51	14	total	total	ADJ
fnp-3528	51	15	and	and	CCONJ
fnp-3528	51	16	phosphorylated	phosphorylate	VERB
fnp-3528	51	17	protein	protein	NOUN
fnp-3528	51	18	tau	tau	NOUN
fnp-3528	51	19	,	,	PUNCT
fnp-3528	51	20	suggesting	suggest	VERB
fnp-3528	51	21	a	a	DET
fnp-3528	51	22	link	link	NOUN
fnp-3528	51	23	between	between	ADP
fnp-3528	51	24	the	the	DET
fnp-3528	51	25	dysfunction	dysfunction	NOUN
fnp-3528	51	26	of	of	ADP
fnp-3528	51	27	hdl	hdl	NOUN
fnp-3528	51	28	-	-	PUNCT
fnp-3528	51	29	like	like	ADJ
fnp-3528	51	30	particle	particle	NOUN
fnp-3528	51	31	in	in	ADP
fnp-3528	51	32	csf	csf	NOUN
fnp-3528	51	33	and	and	CCONJ
fnp-3528	51	34	neurodegeneration	neurodegeneration	NOUN
fnp-3528	51	35	.	.	PUNCT
fnp-3528	52	1	apart	apart	ADV
fnp-3528	52	2	from	from	ADP
fnp-3528	52	3	the	the	DET
fnp-3528	52	4	indirect	indirect	ADJ
fnp-3528	52	5	link	link	NOUN
fnp-3528	52	6	via	via	ADP
fnp-3528	52	7	apoe	apoe	NOUN
fnp-3528	52	8	,	,	PUNCT
fnp-3528	52	9	a	a	DET
fnp-3528	52	10	direct	direct	ADJ
fnp-3528	52	11	link	link	NOUN
fnp-3528	52	12	between	between	ADP
fnp-3528	52	13	abca1	abca1	NOUN
fnp-3528	52	14	and	and	CCONJ
fnp-3528	52	15	ad	ad	NOUN
fnp-3528	52	16	has	have	AUX
fnp-3528	52	17	also	also	ADV
fnp-3528	52	18	been	be	AUX
fnp-3528	52	19	subject	subject	ADJ
fnp-3528	52	20	to	to	ADP
fnp-3528	52	21	investigation	investigation	NOUN
fnp-3528	52	22	.	.	PUNCT
fnp-3528	53	1	expression	expression	NOUN
fnp-3528	53	2	of	of	ADP
fnp-3528	53	3	hippocampal	hippocampal	ADJ
fnp-3528	53	4	abca1	abca1	NOUN
fnp-3528	53	5	was	be	AUX
fnp-3528	53	6	elevated	elevate	VERB
fnp-3528	53	7	on	on	ADP
fnp-3528	53	8	both	both	CCONJ
fnp-3528	53	9	the	the	DET
fnp-3528	53	10	mrna	mrna	NOUN
fnp-3528	53	11	and	and	CCONJ
fnp-3528	53	12	protein	protein	NOUN
fnp-3528	53	13	levels	level	NOUN
fnp-3528	53	14	and	and	CCONJ
fnp-3528	53	15	was	be	AUX
fnp-3528	53	16	positively	positively	ADV
fnp-3528	53	17	correlated	correlate	VERB
fnp-3528	53	18	with	with	ADP
fnp-3528	53	19	neuro	neuro	NOUN
fnp-3528	53	20	-	-	PUNCT
fnp-3528	53	21	pathological	pathological	ADJ
fnp-3528	53	22	changes	change	NOUN
fnp-3528	53	23	and	and	CCONJ
fnp-3528	53	24	dementia	dementia	NOUN
fnp-3528	53	25	severity	severity	NOUN
fnp-3528	53	26	in	in	ADP
fnp-3528	53	27	ad	ad	NOUN
fnp-3528	53	28	patients.157	patients.157	NOUN
fnp-3528	53	29	the	the	DET
fnp-3528	53	30	authors	author	NOUN
fnp-3528	53	31	of	of	ADP
fnp-3528	53	32	this	this	DET
fnp-3528	53	33	study	study	NOUN
fnp-3528	53	34	suggested	suggest	VERB
fnp-3528	53	35	that	that	SCONJ
fnp-3528	53	36	the	the	DET
fnp-3528	53	37	observed	observed	ADJ
fnp-3528	53	38	upregulation	upregulation	NOUN
fnp-3528	53	39	of	of	ADP
fnp-3528	53	40	abca1	abca1	NOUN
fnp-3528	53	41	could	could	AUX
fnp-3528	53	42	be	be	AUX
fnp-3528	53	43	interpreted	interpret	VERB
fnp-3528	53	44	as	as	ADP
fnp-3528	53	45	a	a	DET
fnp-3528	53	46	compensatory	compensatory	ADJ
fnp-3528	53	47	attempt	attempt	NOUN
fnp-3528	53	48	to	to	PART
fnp-3528	53	49	clear	clear	VERB
fnp-3528	53	50	aβ	aβ	PRON
fnp-3528	53	51	from	from	ADP
fnp-3528	53	52	the	the	DET
fnp-3528	53	53	brain	brain	NOUN
fnp-3528	53	54	.	.	PUNCT
fnp-3528	54	1	moreover	moreover	ADV
fnp-3528	54	2	,	,	PUNCT
fnp-3528	54	3	a	a	DET
fnp-3528	54	4	variety	variety	NOUN
fnp-3528	54	5	of	of	ADP
fnp-3528	54	6	studies	study	NOUN
fnp-3528	54	7	investigated	investigate	VERB
fnp-3528	54	8	associations	association	NOUN
fnp-3528	54	9	between	between	ADP
fnp-3528	54	10	single	single	ADJ
fnp-3528	54	11	nucleotide	nucleotide	ADJ
fnp-3528	54	12	polymorphisms	polymorphism	NOUN
fnp-3528	54	13	(	(	PUNCT
fnp-3528	54	14	snp	snp	PROPN
fnp-3528	54	15	)	)	PUNCT
fnp-3528	54	16	in	in	ADP
fnp-3528	54	17	the	the	DET
fnp-3528	54	18	abca1	abca1	NOUN
fnp-3528	54	19	gene	gene	NOUN
fnp-3528	54	20	and	and	CCONJ
fnp-3528	54	21	the	the	DET
fnp-3528	54	22	risk	risk	NOUN
fnp-3528	54	23	for	for	ADP
fnp-3528	54	24	ad,28,108	ad,28,108	NOUN
fnp-3528	54	25	-	-	PUNCT
fnp-3528	54	26	111	111	NUM
fnp-3528	54	27	reporting	reporting	NOUN
fnp-3528	54	28	inconclusive	inconclusive	ADJ
fnp-3528	54	29	results.95,103	results.95,103	VERB
fnp-3528	54	30	a	a	DET
fnp-3528	54	31	meta	meta	ADJ
fnp-3528	54	32	-	-	PUNCT
fnp-3528	54	33	analysis	analysis	NOUN
fnp-3528	54	34	of	of	ADP
fnp-3528	54	35	several	several	ADJ
fnp-3528	54	36	studies	study	NOUN
fnp-3528	54	37	identified	identify	VERB
fnp-3528	54	38	the	the	DET
fnp-3528	54	39	abca1	abca1	NOUN
fnp-3528	54	40	rs2422493	rs2422493	NOUN
fnp-3528	54	41	(	(	PUNCT
fnp-3528	54	42	c477	c477	PROPN
fnp-3528	54	43	t	t	PROPN
fnp-3528	54	44	)	)	PUNCT
fnp-3528	54	45	polymorphism	polymorphism	NOUN
fnp-3528	54	46	as	as	ADP
fnp-3528	54	47	a	a	DET
fnp-3528	54	48	risk	risk	NOUN
fnp-3528	54	49	factor	factor	NOUN
fnp-3528	54	50	for	for	ADP
fnp-3528	54	51	ad	ad	NOUN
fnp-3528	54	52	while	while	SCONJ
fnp-3528	54	53	no	no	DET
fnp-3528	54	54	association	association	NOUN
fnp-3528	54	55	was	be	AUX
fnp-3528	54	56	found	find	VERB
fnp-3528	54	57	for	for	ADP
fnp-3528	54	58	the	the	DET
fnp-3528	54	59	rs2066718	rs2066718	PROPN
fnp-3528	54	60	(	(	PUNCT
fnp-3528	54	61	v771	v771	NUM
fnp-3528	54	62	m	m	NOUN
fnp-3528	54	63	)	)	PUNCT
fnp-3528	54	64	or	or	CCONJ
fnp-3528	54	65	rs1800977	rs1800977	PROPN
fnp-3528	54	66	(	(	PUNCT
fnp-3528	54	67	c14	c14	PROPN
fnp-3528	54	68	t	t	PROPN
fnp-3528	54	69	)	)	PUNCT
fnp-3528	54	70	polymorphisms.111	polymorphisms.111	PROPN
fnp-3528	54	71	this	this	DET
fnp-3528	54	72	risk	risk	NOUN
fnp-3528	54	73	effect	effect	NOUN
fnp-3528	54	74	for	for	ADP
fnp-3528	54	75	rs2422493	rs2422493	PROPN
fnp-3528	54	76	was	be	AUX
fnp-3528	54	77	confirmed	confirm	VERB
fnp-3528	54	78	in	in	ADP
fnp-3528	54	79	a	a	DET
fnp-3528	54	80	recent	recent	ADJ
fnp-3528	54	81	genetic	genetic	ADJ
fnp-3528	54	82	variant	variant	NOUN
fnp-3528	54	83	association	association	NOUN
fnp-3528	54	84	study	study	NOUN
fnp-3528	54	85	that	that	SCONJ
fnp-3528	54	86	,	,	PUNCT
fnp-3528	54	87	in	in	ADP
fnp-3528	54	88	contrast	contrast	NOUN
fnp-3528	54	89	to	to	ADP
fnp-3528	54	90	the	the	DET
fnp-3528	54	91	meta	meta	ADJ
fnp-3528	54	92	-	-	PUNCT
fnp-3528	54	93	analysis	analysis	NOUN
fnp-3528	54	94	,	,	PUNCT
fnp-3528	54	95	also	also	ADV
fnp-3528	54	96	reported	report	VERB
fnp-3528	54	97	an	an	DET
fnp-3528	54	98	increased	increase	VERB
fnp-3528	54	99	ad	ad	NOUN
fnp-3528	54	100	risk	risk	NOUN
fnp-3528	54	101	for	for	ADP
fnp-3528	54	102	rs2066718	rs2066718	PROPN
fnp-3528	54	103	and	and	CCONJ
fnp-3528	54	104	a	a	DET
fnp-3528	54	105	decreased	decrease	VERB
fnp-3528	54	106	ad	ad	NOUN
fnp-3528	54	107	risk	risk	NOUN
fnp-3528	54	108	for	for	ADP
fnp-3528	54	109	rs1800977.109	rs1800977.109	VERB
fnp-3528	54	110	further	further	ADJ
fnp-3528	54	111	genetic	genetic	PROPN
fnp-3528	54	112	association	association	NOUN
fnp-3528	54	113	studies	study	NOUN
fnp-3528	54	114	and	and	CCONJ
fnp-3528	54	115	meta	meta	NOUN
fnp-3528	54	116	-	-	PUNCT
fnp-3528	54	117	analyses	analysis	NOUN
fnp-3528	54	118	are	be	AUX
fnp-3528	54	119	necessary	necessary	ADJ
fnp-3528	54	120	to	to	PART
fnp-3528	54	121	search	search	VERB
fnp-3528	54	122	for	for	ADP
fnp-3528	54	123	potential	potential	ADJ
fnp-3528	54	124	associations	association	NOUN
fnp-3528	54	125	between	between	ADP
fnp-3528	54	126	abca1	abca1	NOUN
fnp-3528	54	127	polymorphisms	polymorphism	NOUN
fnp-3528	54	128	and	and	CCONJ
fnp-3528	54	129	ad	ad	NOUN
fnp-3528	54	130	risk	risk	NOUN
fnp-3528	54	131	.	.	PUNCT
fnp-3528	55	1	in	in	ADP
fnp-3528	55	2	a	a	DET
fnp-3528	55	3	recent	recent	ADJ
fnp-3528	55	4	ad	ad	NOUN
fnp-3528	55	5	gwas	gwas	NOUN
fnp-3528	55	6	,	,	PUNCT
fnp-3528	55	7	the	the	DET
fnp-3528	55	8	rs1800978	rs1800978	NOUN
fnp-3528	55	9	polymorphism	polymorphism	NOUN
fnp-3528	55	10	in	in	ADP
fnp-3528	55	11	the	the	DET
fnp-3528	55	12	abca1	abca1	NOUN
fnp-3528	55	13	gene	gene	NOUN
fnp-3528	55	14	was	be	AUX
fnp-3528	55	15	identified	identify	VERB
fnp-3528	55	16	as	as	ADP
fnp-3528	55	17	the	the	DET
fnp-3528	55	18	lead	lead	NOUN
fnp-3528	55	19	snp	snp	VERB
fnp-3528	55	20	in	in	ADP
fnp-3528	55	21	a	a	DET
fnp-3528	55	22	new	new	ADJ
fnp-3528	55	23	genome	genome	NOUN
fnp-3528	55	24	-	-	PUNCT
fnp-3528	55	25	wide	wide	ADJ
fnp-3528	55	26	significant	significant	ADJ
fnp-3528	55	27	locus.158	locus.158	PROPN
fnp-3528	55	28	the	the	DET
fnp-3528	55	29	association	association	NOUN
fnp-3528	55	30	of	of	ADP
fnp-3528	55	31	genetic	genetic	ADJ
fnp-3528	55	32	variants	variant	NOUN
fnp-3528	55	33	of	of	ADP
fnp-3528	55	34	the	the	DET
fnp-3528	55	35	abca1	abca1	NOUN
fnp-3528	55	36	gene	gene	NOUN
fnp-3528	55	37	with	with	ADP
fnp-3528	55	38	ad	ad	NOUN
fnp-3528	55	39	risk	risk	NOUN
fnp-3528	55	40	was	be	AUX
fnp-3528	55	41	confirmed	confirm	VERB
fnp-3528	55	42	by	by	ADP
fnp-3528	55	43	exome	exome	NOUN
fnp-3528	55	44	sequencing	sequence	VERB
fnp-3528	55	45	data	datum	NOUN
fnp-3528	55	46	analysis	analysis	NOUN
fnp-3528	55	47	from	from	ADP
fnp-3528	55	48	32,558	32,558	NUM
fnp-3528	55	49	individuals.158	individuals.158	NOUN
fnp-3528	55	50	the	the	DET
fnp-3528	55	51	study	study	NOUN
fnp-3528	55	52	identified	identify	VERB
fnp-3528	55	53	around	around	ADP
fnp-3528	55	54	120	120	NUM
fnp-3528	55	55	variants	variant	NOUN
fnp-3528	55	56	that	that	PRON
fnp-3528	55	57	have	have	VERB
fnp-3528	55	58	an	an	DET
fnp-3528	55	59	increased	increase	VERB
fnp-3528	55	60	frequency	frequency	NOUN
fnp-3528	55	61	in	in	ADP
fnp-3528	55	62	early	early	ADJ
fnp-3528	55	63	-	-	PUNCT
fnp-3528	55	64	onset	onset	NOUN
fnp-3528	55	65	ad	ad	NOUN
fnp-3528	55	66	(	(	PUNCT
fnp-3528	55	67	eoad	eoad	NOUN
fnp-3528	55	68	;	;	PUNCT
fnp-3528	55	69	1.5	1.5	NUM
fnp-3528	55	70	%	%	NOUN
fnp-3528	55	71	)	)	PUNCT
fnp-3528	55	72	and	and	CCONJ
fnp-3528	55	73	late	late	ADJ
fnp-3528	55	74	-	-	PUNCT
fnp-3528	55	75	onset	onset	NOUN
fnp-3528	55	76	ad	ad	NOUN
fnp-3528	55	77	(	(	PUNCT
fnp-3528	55	78	load	load	NOUN
fnp-3528	55	79	;	;	PUNCT
fnp-3528	55	80	1.1	1.1	NUM
fnp-3528	55	81	%	%	NOUN
fnp-3528	55	82	)	)	PUNCT
fnp-3528	55	83	cases	case	NOUN
fnp-3528	55	84	,	,	PUNCT
fnp-3528	55	85	compared	compare	VERB
fnp-3528	55	86	to	to	ADP
fnp-3528	55	87	0.5	0.5	NUM
fnp-3528	55	88	%	%	NOUN
fnp-3528	55	89	of	of	ADP
fnp-3528	55	90	all	all	DET
fnp-3528	55	91	controls	control	NOUN
fnp-3528	55	92	.	.	PUNCT
fnp-3528	56	1	the	the	DET
fnp-3528	56	2	data	datum	NOUN
fnp-3528	56	3	demonstrated	demonstrate	VERB
fnp-3528	56	4	that	that	SCONJ
fnp-3528	56	5	ad	ad	NOUN
fnp-3528	56	6	-	-	PUNCT
fnp-3528	56	7	association	association	NOUN
fnp-3528	56	8	was	be	AUX
fnp-3528	56	9	mainly	mainly	ADV
fnp-3528	56	10	explained	explain	VERB
fnp-3528	56	11	by	by	ADP
fnp-3528	56	12	extremely	extremely	ADV
fnp-3528	56	13	rare	rare	ADJ
fnp-3528	56	14	variants	variant	NOUN
fnp-3528	56	15	,	,	PUNCT
fnp-3528	56	16	but	but	CCONJ
fnp-3528	56	17	also	also	ADV
fnp-3528	56	18	by	by	ADP
fnp-3528	56	19	a	a	DET
fnp-3528	56	20	smaller	small	ADJ
fnp-3528	56	21	number	number	NOUN
fnp-3528	56	22	of	of	ADP
fnp-3528	56	23	more	more	ADJ
fnp-3528	56	24	common	common	ADJ
fnp-3528	56	25	variants	variant	NOUN
fnp-3528	56	26	,	,	PUNCT
fnp-3528	56	27	e.g.	e.g.	ADV
fnp-3528	56	28	,	,	PUNCT
fnp-3528	56	29	n1800h.159	n1800h.159	NOUN
fnp-3528	56	30	intriguingly	intriguingly	ADV
fnp-3528	56	31	,	,	PUNCT
fnp-3528	56	32	loss	loss	NOUN
fnp-3528	56	33	of	of	ADP
fnp-3528	56	34	function	function	NOUN
fnp-3528	56	35	and	and	CCONJ
fnp-3528	56	36	missense	missense	NOUN
fnp-3528	56	37	variants	variant	NOUN
fnp-3528	56	38	in	in	ADP
fnp-3528	56	39	the	the	DET
fnp-3528	56	40	abca1	abca1	NOUN
fnp-3528	56	41	gene	gene	NOUN
fnp-3528	56	42	were	be	AUX
fnp-3528	56	43	respectively	respectively	ADV
fnp-3528	56	44	associated	associate	VERB
fnp-3528	56	45	with	with	ADP
fnp-3528	56	46	a	a	DET
fnp-3528	56	47	4.7	4.7	NUM
fnp-3528	56	48	-	-	ADJ
fnp-3528	56	49	fold	fold	ADJ
fnp-3528	56	50	(	(	PUNCT
fnp-3528	56	51	95%ci	95%ci	NUM
fnp-3528	56	52	2.2	2.2	NUM
fnp-3528	56	53	-	-	SYM
fnp-3528	56	54	10.3	10.3	NUM
fnp-3528	56	55	)	)	PUNCT
fnp-3528	56	56	and	and	CCONJ
fnp-3528	56	57	2.7	2.7	NUM
fnp-3528	56	58	-	-	ADJ
fnp-3528	56	59	fold	fold	ADJ
fnp-3528	56	60	(	(	PUNCT
fnp-3528	56	61	95%ci	95%ci	NUM
fnp-3528	56	62	1.9	1.9	NUM
fnp-3528	56	63	-	-	SYM
fnp-3528	56	64	3.8	3.8	NUM
fnp-3528	56	65	)	)	PUNCT
fnp-3528	56	66	increased	increase	VERB
fnp-3528	56	67	eoad	eoad	NOUN
fnp-3528	56	68	risk	risk	NOUN
fnp-3528	56	69	,	,	PUNCT
fnp-3528	56	70	and	and	CCONJ
fnp-3528	56	71	this	this	PRON
fnp-3528	56	72	was	be	AUX
fnp-3528	56	73	lower	low	ADJ
fnp-3528	56	74	for	for	ADP
fnp-3528	56	75	load	load	NOUN
fnp-3528	56	76	cases	case	NOUN
fnp-3528	56	77	suggesting	suggest	VERB
fnp-3528	56	78	that	that	SCONJ
fnp-3528	56	79	the	the	DET
fnp-3528	56	80	burden	burden	NOUN
fnp-3528	56	81	of	of	ADP
fnp-3528	56	82	damaging	damaging	ADJ
fnp-3528	56	83	abca1	abca1	NOUN
fnp-3528	56	84	variants	variant	NOUN
fnp-3528	56	85	was	be	AUX
fnp-3528	56	86	concentrated	concentrate	VERB
fnp-3528	56	87	in	in	ADP
fnp-3528	56	88	younger	young	ADJ
fnp-3528	56	89	ad	ad	NOUN
fnp-3528	56	90	patients	patient	NOUN
fnp-3528	56	91	.	.	PUNCT
fnp-3528	57	1	additionally	additionally	ADV
fnp-3528	57	2	,	,	PUNCT
fnp-3528	57	3	some	some	DET
fnp-3528	57	4	long	long	ADJ
fnp-3528	57	5	non	non	ADJ
fnp-3528	57	6	-	-	ADJ
fnp-3528	57	7	coding	coding	ADJ
fnp-3528	57	8	(	(	PUNCT
fnp-3528	57	9	lnc	lnc	PROPN
fnp-3528	57	10	)	)	PUNCT
fnp-3528	57	11	rnas	rna	NOUN
fnp-3528	57	12	such	such	ADJ
fnp-3528	57	13	as	as	ADP
fnp-3528	57	14	lncrna	lncrna	NOUN
fnp-3528	57	15	loc286367	loc286367	NOUN
fnp-3528	57	16	have	have	AUX
fnp-3528	57	17	been	be	AUX
fnp-3528	57	18	shown	show	VERB
fnp-3528	57	19	to	to	PART
fnp-3528	57	20	affect	affect	VERB
fnp-3528	57	21	abca1	abca1	NOUN
fnp-3528	57	22	expression.160	expression.160	PRON
fnp-3528	57	23	lncrna	lncrna	NOUN
fnp-3528	57	24	loc286367	loc286367	NOUN
fnp-3528	57	25	and	and	CCONJ
fnp-3528	57	26	abca1	abca1	NOUN
fnp-3528	57	27	are	be	AUX
fnp-3528	57	28	located	locate	VERB
fnp-3528	57	29	on	on	ADP
fnp-3528	57	30	the	the	DET
fnp-3528	57	31	same	same	ADJ
fnp-3528	57	32	chromosome	chromosome	NOUN
fnp-3528	57	33	but	but	CCONJ
fnp-3528	57	34	are	be	AUX
fnp-3528	57	35	transcribed	transcribe	VERB
fnp-3528	57	36	in	in	ADP
fnp-3528	57	37	opposite	opposite	ADJ
fnp-3528	57	38	directions	direction	NOUN
fnp-3528	57	39	.	.	PUNCT
fnp-3528	58	1	a	a	DET
fnp-3528	58	2	recent	recent	ADJ
fnp-3528	58	3	study	study	NOUN
fnp-3528	58	4	demonstrated	demonstrate	VERB
fnp-3528	58	5	that	that	SCONJ
fnp-3528	58	6	loc286367	loc286367	NOUN
fnp-3528	58	7	reduces	reduce	VERB
fnp-3528	58	8	abca1	abca1	NOUN
fnp-3528	58	9	expression	expression	NOUN
fnp-3528	58	10	in	in	ADP
fnp-3528	58	11	thp-1	thp-1	ADP
fnp-3528	58	12	macrophages	macrophage	NOUN
fnp-3528	58	13	and	and	CCONJ
fnp-3528	58	14	increases	increase	VERB
fnp-3528	58	15	the	the	DET
fnp-3528	58	16	levels	level	NOUN
fnp-3528	58	17	of	of	ADP
fnp-3528	58	18	proinflammatory	proinflammatory	ADJ
fnp-3528	58	19	cytokines.160	cytokines.160	NOUN
fnp-3528	58	20	the	the	DET
fnp-3528	58	21	role	role	NOUN
fnp-3528	58	22	of	of	ADP
fnp-3528	58	23	abca1	abca1	NOUN
fnp-3528	58	24	in	in	ADP
fnp-3528	58	25	aβ	aβ	NOUN
fnp-3528	58	26	deposition	deposition	NOUN
fnp-3528	58	27	and	and	CCONJ
fnp-3528	58	28	clearance	clearance	NOUN
fnp-3528	58	29	as	as	ADV
fnp-3528	58	30	well	well	ADV
fnp-3528	58	31	as	as	ADP
fnp-3528	58	32	in	in	ADP
fnp-3528	58	33	aβ	aβ	DET
fnp-3528	58	34	deposits	deposit	NOUN
fnp-3528	58	35	-	-	PUNCT
fnp-3528	58	36	related	relate	VERB
fnp-3528	58	37	memory	memory	NOUN
fnp-3528	58	38	deficits	deficit	NOUN
fnp-3528	58	39	has	have	AUX
fnp-3528	58	40	been	be	AUX
fnp-3528	58	41	extensively	extensively	ADV
fnp-3528	58	42	investigated	investigate	VERB
fnp-3528	58	43	in	in	ADP
fnp-3528	58	44	app	app	ADJ
fnp-3528	58	45	-	-	PUNCT
fnp-3528	58	46	transgenic	transgenic	NOUN
fnp-3528	58	47	mouse	mouse	NOUN
fnp-3528	58	48	models	model	NOUN
fnp-3528	58	49	of	of	ADP
fnp-3528	58	50	ad	ad	NOUN
fnp-3528	58	51	.	.	PUNCT
fnp-3528	59	1	the	the	DET
fnp-3528	59	2	lack	lack	NOUN
fnp-3528	59	3	of	of	ADP
fnp-3528	59	4	abca1	abca1	NOUN
fnp-3528	59	5	decreased	decrease	VERB
fnp-3528	59	6	brain	brain	NOUN
fnp-3528	59	7	apoe	apoe	ADJ
fnp-3528	59	8	levels	level	NOUN
fnp-3528	59	9	and	and	CCONJ
fnp-3528	59	10	either	either	CCONJ
fnp-3528	59	11	did	do	AUX
fnp-3528	59	12	not	not	PART
fnp-3528	59	13	affect	affect	VERB
fnp-3528	59	14	or	or	CCONJ
fnp-3528	59	15	increased	increase	VERB
fnp-3528	60	1	aβ	aβ	PRON
fnp-3528	60	2	load.161	load.161	NUM
fnp-3528	60	3	-	-	SYM
fnp-3528	60	4	163	163	NUM
fnp-3528	60	5	a	a	DET
fnp-3528	60	6	recent	recent	ADJ
fnp-3528	60	7	study	study	NOUN
fnp-3528	60	8	utilizing	utilize	VERB
fnp-3528	60	9	shotgun	shotgun	NOUN
fnp-3528	60	10	lipidomics	lipidomic	NOUN
fnp-3528	60	11	experiments	experiment	NOUN
fnp-3528	60	12	demonstrated	demonstrate	VERB
fnp-3528	60	13	a	a	DET
fnp-3528	60	14	common	common	ADJ
fnp-3528	60	15	apoe	apoe	ADJ
fnp-3528	60	16	isoform	isoform	NOUN
fnp-3528	60	17	-	-	PUNCT
fnp-3528	60	18	specific	specific	ADJ
fnp-3528	60	19	phospholipid	phospholipid	NOUN
fnp-3528	60	20	signature	signature	NOUN
fnp-3528	60	21	between	between	ADP
fnp-3528	60	22	human	human	PROPN
fnp-3528	60	23	apoe3/3	apoe3/3	PROPN
fnp-3528	60	24	and	and	CCONJ
fnp-3528	60	25	apoe4/4	apoe4/4	ADV
fnp-3528	60	26	ad	ad	NOUN
fnp-3528	60	27	brains	brain	NOUN
fnp-3528	60	28	and	and	CCONJ
fnp-3528	60	29	lipoproteins	lipoprotein	NOUN
fnp-3528	60	30	isolated	isolate	VERB
fnp-3528	60	31	from	from	ADP
fnp-3528	60	32	astrocyte	astrocyte	NOUN
fnp-3528	60	33	-	-	PUNCT
fnp-3528	60	34	conditioned	condition	VERB
fnp-3528	60	35	media	medium	NOUN
fnp-3528	60	36	of	of	ADP
fnp-3528	60	37	apoe3	apoe3	NOUN
fnp-3528	60	38	and	and	CCONJ
fnp-3528	60	39	apoe4	apoe4	ADJ
fnp-3528	60	40	mice.164	mice.164	NOUN
fnp-3528	60	41	interestingly	interestingly	ADV
fnp-3528	60	42	,	,	PUNCT
fnp-3528	60	43	the	the	DET
fnp-3528	60	44	lipoproteins	lipoprotein	NOUN
fnp-3528	60	45	derived	derive	VERB
fnp-3528	60	46	from	from	ADP
fnp-3528	60	47	wild	wild	ADJ
fnp-3528	60	48	-	-	PUNCT
fnp-3528	60	49	type	type	NOUN
fnp-3528	60	50	and	and	CCONJ
fnp-3528	60	51	abca1het	abca1het	NOUN
fnp-3528	60	52	mice	mouse	NOUN
fnp-3528	60	53	had	have	VERB
fnp-3528	60	54	phospholipid	phospholipid	NOUN
fnp-3528	60	55	content	content	NOUN
fnp-3528	60	56	apoe3	apoe3	PROPN
fnp-3528	61	1	>	>	X
fnp-3528	62	1	apoe4	apoe4	PROPN
fnp-3528	62	2	>	>	X
fnp-3528	62	3	apoe3het	apoe3het	PROPN
fnp-3528	62	4	>	>	X
fnp-3528	62	5	apoe4het	apoe4het	X
fnp-3528	62	6	suggesting	suggest	VERB
fnp-3528	62	7	that	that	SCONJ
fnp-3528	62	8	the	the	DET
fnp-3528	62	9	combination	combination	NOUN
fnp-3528	62	10	of	of	ADP
fnp-3528	62	11	abca1	abca1	NOUN
fnp-3528	62	12	insufficiency	insufficiency	NOUN
fnp-3528	62	13	and	and	CCONJ
fnp-3528	62	14	apoe4	apoe4	PROPN
fnp-3528	62	15	genotype	genotype	NOUN
fnp-3528	62	16	decreases	decrease	NOUN
fnp-3528	62	17	apoe	apoe	ADP
fnp-3528	62	18	lipidation	lipidation	NOUN
fnp-3528	62	19	even	even	ADV
fnp-3528	62	20	further	far	ADV
fnp-3528	62	21	,	,	PUNCT
fnp-3528	62	22	thus	thus	ADV
fnp-3528	62	23	aggravating	aggravate	VERB
fnp-3528	62	24	apoe4	apoe4	ADJ
fnp-3528	62	25	effect	effect	NOUN
fnp-3528	62	26	.	.	PUNCT
fnp-3528	63	1	these	these	DET
fnp-3528	63	2	findings	finding	NOUN
fnp-3528	63	3	suggest	suggest	VERB
fnp-3528	63	4	that	that	SCONJ
fnp-3528	63	5	poorly	poorly	ADV
fnp-3528	63	6	lipidated	lipidate	VERB
fnp-3528	63	7	apoe	apoe	NOUN
fnp-3528	63	8	may	may	AUX
fnp-3528	63	9	promote	promote	VERB
fnp-3528	63	10	aβ	aβ	PRON
fnp-3528	63	11	aggregation.129,161	aggregation.129,161	NOUN
fnp-3528	63	12	-	-	SYM
fnp-3528	63	13	163	163	NUM
fnp-3528	63	14	in	in	ADP
fnp-3528	63	15	contrast	contrast	NOUN
fnp-3528	63	16	,	,	PUNCT
fnp-3528	63	17	overexpression	overexpression	NOUN
fnp-3528	63	18	of	of	ADP
fnp-3528	63	19	abca1	abca1	NOUN
fnp-3528	63	20	in	in	ADP
fnp-3528	63	21	an	an	DET
fnp-3528	63	22	app	app	ADJ
fnp-3528	63	23	-	-	PUNCT
fnp-3528	63	24	transgenic	transgenic	NOUN
fnp-3528	63	25	mouse	mouse	NOUN
fnp-3528	63	26	model	model	NOUN
fnp-3528	63	27	resulted	result	VERB
fnp-3528	63	28	in	in	ADP
fnp-3528	63	29	increased	increase	VERB
fnp-3528	63	30	lipidation	lipidation	NOUN
fnp-3528	63	31	,	,	PUNCT
fnp-3528	63	32	albeit	albeit	SCONJ
fnp-3528	63	33	reduced	reduced	ADJ
fnp-3528	63	34	brain	brain	NOUN
fnp-3528	63	35	levels	level	NOUN
fnp-3528	63	36	of	of	ADP
fnp-3528	63	37	apoe	apoe	NOUN
fnp-3528	63	38	and	and	CCONJ
fnp-3528	63	39	decreased	decrease	VERB
fnp-3528	63	40	aβ	aβ	DET
fnp-3528	63	41	load	load	NOUN
fnp-3528	63	42	,	,	PUNCT
fnp-3528	63	43	implying	imply	VERB
fnp-3528	63	44	that	that	SCONJ
fnp-3528	63	45	highly	highly	ADV
fnp-3528	63	46	lipidated	lipidate	VERB
fnp-3528	63	47	apoe	apoe	NOUN
fnp-3528	63	48	may	may	AUX
fnp-3528	63	49	reduce	reduce	VERB
fnp-3528	63	50	aβ	aβ	PRON
fnp-3528	63	51	aggregation	aggregation	NOUN
fnp-3528	63	52	propensity.127	propensity.127	NOUN
fnp-3528	63	53	this	this	PRON
fnp-3528	63	54	is	be	AUX
fnp-3528	63	55	supported	support	VERB
fnp-3528	63	56	by	by	ADP
fnp-3528	63	57	findings	finding	NOUN
fnp-3528	63	58	of	of	ADP
fnp-3528	63	59	deane	deane	PROPN
fnp-3528	63	60	et	et	PROPN
fnp-3528	63	61	al	al	PROPN
fnp-3528	63	62	.	.	PROPN
fnp-3528	63	63	,	,	PUNCT
fnp-3528	63	64	who	who	PRON
fnp-3528	63	65	showed	show	VERB
fnp-3528	63	66	that	that	SCONJ
fnp-3528	63	67	different	different	ADJ
fnp-3528	63	68	apoe	apoe	ADJ
fnp-3528	63	69	isoforms	isoform	NOUN
fnp-3528	63	70	may	may	AUX
fnp-3528	63	71	differentially	differentially	ADV
fnp-3528	63	72	disrupt	disrupt	VERB
fnp-3528	63	73	aβ	aβ	ADP
fnp-3528	63	74	clearance	clearance	NOUN
fnp-3528	63	75	from	from	ADP
fnp-3528	63	76	mice	mouse	NOUN
fnp-3528	63	77	brains.165	brains.165	VERB
fnp-3528	63	78	a	a	DET
fnp-3528	63	79	stable	stable	ADJ
fnp-3528	63	80	isotope	isotope	NOUN
fnp-3528	63	81	-	-	PUNCT
fnp-3528	63	82	labelling	labelling	NOUN
fnp-3528	63	83	kinetic	kinetic	ADJ
fnp-3528	63	84	study	study	NOUN
fnp-3528	63	85	in	in	ADP
fnp-3528	63	86	an	an	DET
fnp-3528	63	87	app	app	ADJ
fnp-3528	63	88	-	-	PUNCT
fnp-3528	63	89	transgenic	transgenic	NOUN
fnp-3528	63	90	mouse	mouse	NOUN
fnp-3528	63	91	model	model	NOUN
fnp-3528	63	92	either	either	CCONJ
fnp-3528	63	93	lacking	lacking	ADJ
fnp-3528	63	94	abca1	abca1	NOUN
fnp-3528	63	95	or	or	CCONJ
fnp-3528	63	96	overexpressing	overexpresse	VERB
fnp-3528	63	97	abca1	abca1	NOUN
fnp-3528	63	98	demonstrated	demonstrate	VERB
fnp-3528	63	99	increased	increase	VERB
fnp-3528	63	100	apoe	apoe	ADJ
fnp-3528	63	101	clearance	clearance	NOUN
fnp-3528	63	102	in	in	ADP
fnp-3528	63	103	both	both	DET
fnp-3528	63	104	abca1	abca1	NOUN
fnp-3528	63	105	knock	knock	VERB
fnp-3528	63	106	-	-	PUNCT
fnp-3528	63	107	out	out	NOUN
fnp-3528	63	108	and	and	CCONJ
fnp-3528	63	109	abca1	abca1	NOUN
fnp-3528	63	110	-	-	PUNCT
fnp-3528	63	111	overexpressing	overexpresse	VERB
fnp-3528	63	112	mice	mouse	NOUN
fnp-3528	63	113	,	,	PUNCT
fnp-3528	63	114	but	but	CCONJ
fnp-3528	63	115	did	do	AUX
fnp-3528	63	116	not	not	PART
fnp-3528	63	117	reveal	reveal	VERB
fnp-3528	63	118	any	any	DET
fnp-3528	63	119	effect	effect	NOUN
fnp-3528	63	120	on	on	ADP
fnp-3528	63	121	aβ	aβ	ADP
fnp-3528	63	122	clearance	clearance	NOUN
fnp-3528	63	123	or	or	CCONJ
fnp-3528	63	124	production	production	NOUN
fnp-3528	63	125	,	,	PUNCT
fnp-3528	63	126	suggesting	suggest	VERB
fnp-3528	63	127	that	that	DET
fnp-3528	63	128	abca1	abca1	NOUN
fnp-3528	63	129	may	may	AUX
fnp-3528	63	130	regulate	regulate	VERB
fnp-3528	63	131	aβ	aβ	ADP
fnp-3528	63	132	deposition	deposition	NOUN
fnp-3528	63	133	by	by	ADP
fnp-3528	63	134	a	a	DET
fnp-3528	63	135	mechanism	mechanism	NOUN
fnp-3528	63	136	other	other	ADJ
fnp-3528	63	137	than	than	ADP
fnp-3528	63	138	altering	alter	VERB
fnp-3528	63	139	aβ	aβ	DET
fnp-3528	63	140	metabolism.166	metabolism.166	NOUN
fnp-3528	63	141	in	in	ADP
fnp-3528	63	142	contrast	contrast	NOUN
fnp-3528	63	143	,	,	PUNCT
fnp-3528	63	144	a	a	DET
fnp-3528	63	145	study	study	NOUN
fnp-3528	63	146	assessing	assess	VERB
fnp-3528	63	147	the	the	DET
fnp-3528	63	148	clearance	clearance	NOUN
fnp-3528	63	149	of	of	ADP
fnp-3528	63	150	intracerebrally	intracerebrally	ADV
fnp-3528	63	151	injected	inject	VERB
fnp-3528	63	152	125i	125i	NOUN
fnp-3528	63	153	-	-	PUNCT
fnp-3528	63	154	aβ	aβ	NOUN
fnp-3528	63	155	from	from	ADP
fnp-3528	63	156	the	the	DET
fnp-3528	63	157	brain	brain	NOUN
fnp-3528	63	158	reported	report	VERB
fnp-3528	63	159	that	that	SCONJ
fnp-3528	63	160	abca1	abca1	NOUN
fnp-3528	63	161	-	-	PUNCT
fnp-3528	63	162	deficiency	deficiency	NOUN
fnp-3528	63	163	decreased	decrease	VERB
fnp-3528	63	164	aβ	aβ	DET
fnp-3528	63	165	clearance	clearance	NOUN
fnp-3528	63	166	in	in	ADP
fnp-3528	63	167	non	non	ADJ
fnp-3528	63	168	-	-	ADJ
fnp-3528	63	169	app	app	ADJ
fnp-3528	63	170	-	-	PUNCT
fnp-3528	63	171	transgenic	transgenic	ADJ
fnp-3528	63	172	mice.167	mice.167	NOUN
fnp-3528	63	173	furthermore	furthermore	ADV
fnp-3528	63	174	,	,	PUNCT
fnp-3528	63	175	knock	knock	VERB
fnp-3528	63	176	-	-	PUNCT
fnp-3528	63	177	out	out	NOUN
fnp-3528	63	178	of	of	ADP
fnp-3528	63	179	abca1	abca1	NOUN
fnp-3528	63	180	was	be	AUX
fnp-3528	63	181	found	find	VERB
fnp-3528	63	182	to	to	PART
fnp-3528	63	183	augment	augment	VERB
fnp-3528	63	184	the	the	DET
fnp-3528	63	185	dissemination	dissemination	NOUN
fnp-3528	63	186	of	of	ADP
fnp-3528	63	187	intracerebrally	intracerebrally	ADV
fnp-3528	63	188	injected	inject	VERB
fnp-3528	63	189	,	,	PUNCT
fnp-3528	63	190	brain	brain	NOUN
fnp-3528	63	191	-	-	PUNCT
fnp-3528	63	192	derived	derive	VERB
fnp-3528	63	193	aβ	aβ	NOUN
fnp-3528	63	194	seeds	seed	NOUN
fnp-3528	63	195	in	in	ADP
fnp-3528	63	196	app	app	ADJ
fnp-3528	63	197	-	-	PUNCT
fnp-3528	63	198	transgenic	transgenic	ADJ
fnp-3528	63	199	mice.167	mice.167	ADJ
fnp-3528	63	200	haplodeficiency	haplodeficiency	NOUN
fnp-3528	63	201	of	of	ADP
fnp-3528	63	202	abca1	abca1	NOUN
fnp-3528	63	203	led	lead	VERB
fnp-3528	63	204	to	to	ADP
fnp-3528	63	205	decreased	decrease	VERB
fnp-3528	63	206	brain	brain	NOUN
fnp-3528	63	207	apoe	apoe	NOUN
fnp-3528	63	208	levels	level	NOUN
fnp-3528	63	209	and	and	CCONJ
fnp-3528	63	210	increased	increase	VERB
fnp-3528	63	211	aβ	aβ	DET
fnp-3528	63	212	oligomer	oligomer	ADJ
fnp-3528	63	213	levels	level	NOUN
fnp-3528	63	214	but	but	CCONJ
fnp-3528	63	215	did	do	AUX
fnp-3528	63	216	not	not	PART
fnp-3528	63	217	affect	affect	VERB
fnp-3528	63	218	aβ	aβ	PRON
fnp-3528	63	219	deposition	deposition	NOUN
fnp-3528	63	220	in	in	ADP
fnp-3528	63	221	app	app	ADJ
fnp-3528	63	222	-	-	PUNCT
fnp-3528	63	223	transgenic	transgenic	ADJ
fnp-3528	63	224	mice.168	mice.168	NOUN
fnp-3528	63	225	however	however	ADV
fnp-3528	63	226	,	,	PUNCT
fnp-3528	63	227	both	both	DET
fnp-3528	63	228	haplodeficiency	haplodeficiency	NOUN
fnp-3528	63	229	and	and	CCONJ
fnp-3528	63	230	homozygous	homozygous	ADJ
fnp-3528	63	231	knock	knock	NOUN
fnp-3528	63	232	-	-	PUNCT
fnp-3528	63	233	out	out	NOUN
fnp-3528	63	234	of	of	ADP
fnp-3528	63	235	abca1	abca1	NOUN
fnp-3528	63	236	aggravated	aggravate	VERB
fnp-3528	63	237	cognitive	cognitive	ADJ
fnp-3528	63	238	deficits	deficit	NOUN
fnp-3528	63	239	in	in	ADP
fnp-3528	63	240	app	app	ADJ
fnp-3528	63	241	-	-	PUNCT
fnp-3528	63	242	transgenic	transgenic	ADJ
fnp-3528	63	243	mice.152,167,168	mice.152,167,168	NOUN
fnp-3528	63	244	lastly	lastly	ADV
fnp-3528	63	245	,	,	PUNCT
fnp-3528	63	246	the	the	DET
fnp-3528	63	247	lack	lack	NOUN
fnp-3528	63	248	of	of	ADP
fnp-3528	63	249	one	one	NUM
fnp-3528	63	250	copy	copy	NOUN
fnp-3528	63	251	of	of	ADP
fnp-3528	63	252	abca1	abca1	NOUN
fnp-3528	63	253	exacerbated	exacerbate	VERB
fnp-3528	63	254	memory	memory	NOUN
fnp-3528	63	255	deficits	deficit	NOUN
fnp-3528	63	256	,	,	PUNCT
fnp-3528	63	257	decreased	decrease	VERB
fnp-3528	63	258	aβ	aβ	DET
fnp-3528	63	259	clearance	clearance	NOUN
fnp-3528	63	260	,	,	PUNCT
fnp-3528	63	261	and	and	CCONJ
fnp-3528	63	262	increased	increase	VERB
fnp-3528	63	263	aβ	aβ	PRON
fnp-3528	63	264	load	load	NOUN
fnp-3528	63	265	in	in	ADP
fnp-3528	63	266	app	app	ADJ
fnp-3528	63	267	-	-	PUNCT
fnp-3528	63	268	transgenic	transgenic	NOUN
fnp-3528	63	269	mice	mouse	NOUN
fnp-3528	63	270	expressing	express	VERB
fnp-3528	63	271	human	human	ADJ
fnp-3528	63	272	apoe4	apoe4	PROPN
fnp-3528	63	273	but	but	CCONJ
fnp-3528	63	274	not	not	PART
fnp-3528	63	275	in	in	ADP
fnp-3528	63	276	app	app	ADJ
fnp-3528	63	277	-	-	PUNCT
fnp-3528	63	278	transgenic	transgenic	ADJ
fnp-3528	63	279	mice	mouse	NOUN
fnp-3528	63	280	expressing	express	VERB
fnp-3528	63	281	human	human	ADJ
fnp-3528	63	282	apoe3.169	apoe3.169	NOUN
fnp-3528	63	283	abca2	abca2	NOUN
fnp-3528	63	284	abca2	abca2	PROPN
fnp-3528	63	285	is	be	AUX
fnp-3528	63	286	predominantly	predominantly	ADV
fnp-3528	63	287	,	,	PUNCT
fnp-3528	63	288	but	but	CCONJ
fnp-3528	63	289	not	not	PART
fnp-3528	63	290	exclusively	exclusively	ADV
fnp-3528	63	291	,	,	PUNCT
fnp-3528	63	292	expressed	express	VERB
fnp-3528	63	293	in	in	ADP
fnp-3528	63	294	the	the	DET
fnp-3528	63	295	brain	brain	NOUN
fnp-3528	63	296	,	,	PUNCT
fnp-3528	63	297	where	where	SCONJ
fnp-3528	63	298	it	it	PRON
fnp-3528	63	299	can	can	AUX
fnp-3528	63	300	be	be	AUX
fnp-3528	63	301	found	find	VERB
fnp-3528	63	302	in	in	ADP
fnp-3528	63	303	glial	glial	ADJ
fnp-3528	63	304	cells	cell	NOUN
fnp-3528	63	305	and	and	CCONJ
fnp-3528	63	306	neurons.170	neurons.170	NOUN
fnp-3528	63	307	-	-	PUNCT
fnp-3528	63	308	173	173	NUM
fnp-3528	63	309	on	on	ADP
fnp-3528	63	310	the	the	DET
fnp-3528	63	311	subcellular	subcellular	ADJ
fnp-3528	63	312	level	level	NOUN
fnp-3528	63	313	,	,	PUNCT
fnp-3528	63	314	abca2	abca2	NOUN
fnp-3528	63	315	is	be	AUX
fnp-3528	63	316	located	locate	VERB
fnp-3528	63	317	in	in	ADP
fnp-3528	63	318	endoand	endoand	PROPN
fnp-3528	63	319	lysosomal	lysosomal	ADJ
fnp-3528	63	320	membranes	membrane	NOUN
fnp-3528	63	321	,	,	PUNCT
fnp-3528	63	322	facilitating	facilitate	VERB
fnp-3528	63	323	the	the	DET
fnp-3528	63	324	sequestration	sequestration	NOUN
fnp-3528	63	325	of	of	ADP
fnp-3528	63	326	waste	waste	NOUN
fnp-3528	63	327	substances	substance	NOUN
fnp-3528	63	328	into	into	ADP
fnp-3528	63	329	intracellular	intracellular	ADJ
fnp-3528	63	330	vesicles.172	vesicles.172	NOUN
fnp-3528	63	331	in	in	ADP
fnp-3528	63	332	addition	addition	NOUN
fnp-3528	63	333	,	,	PUNCT
fnp-3528	63	334	it	it	PRON
fnp-3528	63	335	is	be	AUX
fnp-3528	63	336	involved	involve	VERB
fnp-3528	63	337	in	in	ADP
fnp-3528	63	338	myelin	myelin	ADJ
fnp-3528	63	339	lipid	lipid	NOUN
fnp-3528	63	340	transport	transport	NOUN
fnp-3528	63	341	,	,	PUNCT
fnp-3528	63	342	neural	neural	ADJ
fnp-3528	63	343	development	development	NOUN
fnp-3528	63	344	,	,	PUNCT
fnp-3528	63	345	and	and	CCONJ
fnp-3528	63	346	macrophage	macrophage	ADJ
fnp-3528	63	347	activation.30,174,175	activation.30,174,175	NOUN
fnp-3528	63	348	genetic	genetic	ADJ
fnp-3528	63	349	variations	variation	NOUN
fnp-3528	63	350	of	of	ADP
fnp-3528	63	351	abca2	abca2	NOUN
fnp-3528	63	352	were	be	AUX
fnp-3528	63	353	identified	identify	VERB
fnp-3528	63	354	as	as	ADP
fnp-3528	63	355	a	a	DET
fnp-3528	63	356	risk	risk	NOUN
fnp-3528	63	357	factor	factor	NOUN
fnp-3528	63	358	for	for	ADP
fnp-3528	63	359	eoad	eoad	NOUN
fnp-3528	63	360	and	and	CCONJ
fnp-3528	63	361	sporadic	sporadic	ADJ
fnp-3528	63	362	ad.52,176	ad.52,176	NOUN
fnp-3528	63	363	these	these	DET
fnp-3528	63	364	two	two	NUM
fnp-3528	63	365	studies	study	NOUN
fnp-3528	63	366	showed	show	VERB
fnp-3528	63	367	a	a	DET
fnp-3528	63	368	strong	strong	ADJ
fnp-3528	63	369	correlation	correlation	NOUN
fnp-3528	63	370	between	between	ADP
fnp-3528	63	371	rs908832	rs908832	NOUN
fnp-3528	63	372	and	and	CCONJ
fnp-3528	63	373	ad.52,176	ad.52,176	NOUN
fnp-3528	63	374	however	however	ADV
fnp-3528	63	375	,	,	PUNCT
fnp-3528	63	376	a	a	DET
fnp-3528	63	377	later	later	ADJ
fnp-3528	63	378	study	study	NOUN
fnp-3528	63	379	could	could	AUX
fnp-3528	63	380	not	not	PART
fnp-3528	63	381	find	find	VERB
fnp-3528	63	382	a	a	DET
fnp-3528	63	383	link	link	NOUN
fnp-3528	63	384	between	between	ADP
fnp-3528	63	385	this	this	DET
fnp-3528	63	386	snp	snp	NOUN
fnp-3528	63	387	and	and	CCONJ
fnp-3528	63	388	any	any	DET
fnp-3528	63	389	form	form	NOUN
fnp-3528	63	390	of	of	ADP
fnp-3528	63	391	ad.177	ad.177	PROPN
fnp-3528	63	392	in	in	ADP
fnp-3528	63	393	addition	addition	NOUN
fnp-3528	63	394	,	,	PUNCT
fnp-3528	63	395	abca2	abca2	NOUN
fnp-3528	63	396	mrna	mrna	PROPN
fnp-3528	63	397	expression	expression	NOUN
fnp-3528	63	398	was	be	AUX
fnp-3528	63	399	upregulated	upregulate	VERB
fnp-3528	63	400	in	in	ADP
fnp-3528	63	401	ad	ad	NOUN
fnp-3528	63	402	patients	patient	NOUN
fnp-3528	63	403	compared	compare	VERB
fnp-3528	63	404	to	to	ADP
fnp-3528	63	405	controls	control	NOUN
fnp-3528	63	406	suggesting	suggest	VERB
fnp-3528	63	407	abca2	abca2	ADV
fnp-3528	63	408	as	as	ADP
fnp-3528	63	409	a	a	DET
fnp-3528	63	410	biomarker	biomarker	NOUN
fnp-3528	63	411	for	for	ADP
fnp-3528	63	412	differential	differential	ADJ
fnp-3528	63	413	diagnosis	diagnosis	NOUN
fnp-3528	63	414	of	of	ADP
fnp-3528	63	415	ad.178	ad.178	PROPN
fnp-3528	63	416	preclinical	preclinical	ADJ
fnp-3528	63	417	studies	study	NOUN
fnp-3528	63	418	of	of	ADP
fnp-3528	63	419	abca2	abca2	NOUN
fnp-3528	63	420	suggested	suggest	VERB
fnp-3528	63	421	that	that	SCONJ
fnp-3528	63	422	this	this	DET
fnp-3528	63	423	transporter	transporter	NOUN
fnp-3528	63	424	modulates	modulate	VERB
fnp-3528	63	425	aβ	aβ	PRON
fnp-3528	63	426	production	production	NOUN
fnp-3528	63	427	via	via	ADP
fnp-3528	63	428	the	the	DET
fnp-3528	63	429	ldl	ldl	NOUN
fnp-3528	63	430	receptor	receptor	NOUN
fnp-3528	63	431	(	(	PUNCT
fnp-3528	63	432	ldlr).179,180	ldlr).179,180	DET
fnp-3528	63	433	abca2	abca2	NOUN
fnp-3528	63	434	overexpression	overexpression	NOUN
fnp-3528	63	435	increased	increase	VERB
fnp-3528	63	436	ldlr	ldlr	ADJ
fnp-3528	63	437	density	density	NOUN
fnp-3528	63	438	,	,	PUNCT
fnp-3528	63	439	and	and	CCONJ
fnp-3528	63	440	ldlr	ldlr	ADJ
fnp-3528	63	441	deficiency	deficiency	NOUN
fnp-3528	63	442	has	have	AUX
fnp-3528	63	443	been	be	AUX
fnp-3528	63	444	described	describe	VERB
fnp-3528	63	445	to	to	PART
fnp-3528	63	446	enhance	enhance	VERB
fnp-3528	63	447	aβ	aβ	PRON
fnp-3528	64	1	deposition.181	deposition.181	PROPN
fnp-3528	64	2	chen	chen	PROPN
fnp-3528	64	3	et	et	PROPN
fnp-3528	64	4	al	al	PROPN
fnp-3528	64	5	.	.	PROPN
fnp-3528	64	6	reported	report	VERB
fnp-3528	64	7	a	a	DET
fnp-3528	64	8	co	co	NOUN
fnp-3528	64	9	-	-	NOUN
fnp-3528	64	10	localization	localization	NOUN
fnp-3528	64	11	of	of	ADP
fnp-3528	64	12	abca2	abca2	NOUN
fnp-3528	64	13	and	and	CCONJ
fnp-3528	64	14	aβ	aβ	INTJ
fnp-3528	64	15	as	as	ADV
fnp-3528	64	16	well	well	ADV
fnp-3528	64	17	as	as	ADP
fnp-3528	64	18	aβ	aβ	PRON
fnp-3528	64	19	upregulation	upregulation	NOUN
fnp-3528	64	20	in	in	ADP
fnp-3528	64	21	cells	cell	NOUN
fnp-3528	64	22	overexpressing	overexpresse	VERB
fnp-3528	64	23	abca2	abca2	X
fnp-3528	64	24	.	.	PUNCT
fnp-3528	65	1	in	in	ADP
fnp-3528	65	2	addition	addition	NOUN
fnp-3528	65	3	,	,	PUNCT
fnp-3528	65	4	impairment	impairment	NOUN
fnp-3528	65	5	of	of	ADP
fnp-3528	65	6	abca2	abca2	NOUN
fnp-3528	65	7	expression	expression	NOUN
fnp-3528	65	8	using	use	VERB
fnp-3528	65	9	small	small	ADJ
fnp-3528	65	10	interfering	interfere	VERB
fnp-3528	65	11	rna	rna	PROPN
fnp-3528	65	12	(	(	PUNCT
fnp-3528	65	13	sirna	sirna	PROPN
fnp-3528	65	14	)	)	PUNCT
fnp-3528	65	15	was	be	AUX
fnp-3528	65	16	accompanied	accompany	VERB
fnp-3528	65	17	by	by	ADP
fnp-3528	65	18	a	a	DET
fnp-3528	65	19	decrease	decrease	NOUN
fnp-3528	65	20	in	in	ADP
fnp-3528	65	21	aβ	aβ	DET
fnp-3528	65	22	production.182	production.182	PROPN
fnp-3528	65	23	abca2	abca2	NOUN
fnp-3528	65	24	depletion	depletion	NOUN
fnp-3528	65	25	has	have	AUX
fnp-3528	65	26	been	be	AUX
fnp-3528	65	27	shown	show	VERB
fnp-3528	65	28	to	to	PART
fnp-3528	65	29	induce	induce	VERB
fnp-3528	65	30	a	a	DET
fnp-3528	65	31	shift	shift	NOUN
fnp-3528	65	32	from	from	ADP
fnp-3528	65	33	βto	βto	NOUN
fnp-3528	65	34	α	α	NOUN
fnp-3528	65	35	-	-	NOUN
fnp-3528	65	36	secretases	secretase	NOUN
fnp-3528	65	37	and	and	CCONJ
fnp-3528	65	38	thus	thus	ADV
fnp-3528	65	39	,	,	PUNCT
fnp-3528	65	40	a	a	DET
fnp-3528	65	41	reduction	reduction	NOUN
fnp-3528	65	42	of	of	ADP
fnp-3528	65	43	app	app	NOUN
fnp-3528	65	44	processing	processing	NOUN
fnp-3528	65	45	by	by	ADP
fnp-3528	65	46	γ	γ	PROPN
fnp-3528	65	47	-	-	PUNCT
fnp-3528	65	48	secretase.182	secretase.182	NOUN
fnp-3528	65	49	furthermore	furthermore	ADV
fnp-3528	65	50	,	,	PUNCT
fnp-3528	65	51	abca2	abca2	NOUN
fnp-3528	65	52	has	have	AUX
fnp-3528	65	53	been	be	AUX
fnp-3528	65	54	proposed	propose	VERB
fnp-3528	65	55	to	to	PART
fnp-3528	65	56	play	play	VERB
fnp-3528	65	57	a	a	DET
fnp-3528	65	58	role	role	NOUN
fnp-3528	65	59	in	in	ADP
fnp-3528	65	60	aβ	aβ	NOUN
fnp-3528	65	61	production	production	NOUN
fnp-3528	65	62	as	as	SCONJ
fnp-3528	65	63	it	it	PRON
fnp-3528	65	64	has	have	AUX
fnp-3528	65	65	been	be	AUX
fnp-3528	65	66	reported	report	VERB
fnp-3528	65	67	to	to	PART
fnp-3528	65	68	upregulate	upregulate	VERB
fnp-3528	65	69	sphingosine	sphingosine	NOUN
fnp-3528	65	70	in	in	ADP
fnp-3528	65	71	murine	murine	ADJ
fnp-3528	65	72	cells	cell	NOUN
fnp-3528	65	73	and	and	CCONJ
fnp-3528	65	74	,	,	PUNCT
fnp-3528	65	75	therefore	therefore	ADV
fnp-3528	65	76	,	,	PUNCT
fnp-3528	65	77	to	to	PART
fnp-3528	65	78	induce	induce	VERB
fnp-3528	65	79	app	app	NOUN
fnp-3528	65	80	transcription.183	transcription.183	NOUN
fnp-3528	65	81	however	however	ADV
fnp-3528	65	82	,	,	PUNCT
fnp-3528	65	83	another	another	DET
fnp-3528	65	84	study	study	NOUN
fnp-3528	65	85	in	in	ADP
fnp-3528	65	86	human	human	ADJ
fnp-3528	65	87	cells	cell	NOUN
fnp-3528	65	88	could	could	AUX
fnp-3528	65	89	not	not	PART
fnp-3528	65	90	confirm	confirm	VERB
fnp-3528	65	91	the	the	DET
fnp-3528	65	92	modulation	modulation	NOUN
fnp-3528	65	93	of	of	ADP
fnp-3528	65	94	aβ	aβ	NOUN
fnp-3528	65	95	production	production	NOUN
fnp-3528	65	96	or	or	CCONJ
fnp-3528	65	97	cholesterol	cholesterol	NOUN
fnp-3528	65	98	efflux	efflux	NOUN
fnp-3528	65	99	by	by	ADP
fnp-3528	65	100	abca2.184	abca2.184	NOUN
fnp-3528	65	101	thus	thus	ADV
fnp-3528	65	102	,	,	PUNCT
fnp-3528	65	103	further	further	ADJ
fnp-3528	65	104	research	research	NOUN
fnp-3528	65	105	on	on	ADP
fnp-3528	65	106	the	the	DET
fnp-3528	65	107	role	role	NOUN
fnp-3528	65	108	of	of	ADP
fnp-3528	65	109	abca2	abca2	NOUN
fnp-3528	65	110	in	in	ADP
fnp-3528	65	111	ad	ad	NOUN
fnp-3528	65	112	pathogenesis	pathogenesis	NOUN
fnp-3528	65	113	and	and	CCONJ
fnp-3528	65	114	its	its	PRON
fnp-3528	65	115	potential	potential	NOUN
fnp-3528	65	116	as	as	ADP
fnp-3528	65	117	a	a	DET
fnp-3528	65	118	therapeutic	therapeutic	ADJ
fnp-3528	65	119	target	target	NOUN
fnp-3528	65	120	is	be	AUX
fnp-3528	65	121	necessary	necessary	ADJ
fnp-3528	65	122	.	.	PUNCT
fnp-3528	66	1	abca3	abca3	PUNCT
fnp-3528	67	1	despite	despite	SCONJ
fnp-3528	67	2	its	its	PRON
fnp-3528	67	3	initial	initial	ADJ
fnp-3528	67	4	report	report	NOUN
fnp-3528	67	5	of	of	ADP
fnp-3528	67	6	exclusive	exclusive	ADJ
fnp-3528	67	7	lung	lung	NOUN
fnp-3528	67	8	expression,185	expression,185	NOUN
fnp-3528	67	9	abca3	abca3	PUNCT
fnp-3528	67	10	is	be	AUX
fnp-3528	67	11	also	also	ADV
fnp-3528	67	12	found	find	VERB
fnp-3528	67	13	in	in	ADP
fnp-3528	67	14	other	other	ADJ
fnp-3528	67	15	tissues	tissue	NOUN
fnp-3528	67	16	including	include	VERB
fnp-3528	67	17	the	the	DET
fnp-3528	67	18	brain.186,187	brain.186,187	NOUN
fnp-3528	67	19	within	within	ADP
fnp-3528	67	20	the	the	DET
fnp-3528	67	21	brain	brain	NOUN
fnp-3528	67	22	,	,	PUNCT
fnp-3528	67	23	the	the	DET
fnp-3528	67	24	highest	high	ADJ
fnp-3528	67	25	levels	level	NOUN
fnp-3528	67	26	of	of	ADP
fnp-3528	67	27	abca3	abca3	PROPN
fnp-3528	67	28	were	be	AUX
fnp-3528	67	29	found	find	VERB
fnp-3528	67	30	in	in	ADP
fnp-3528	67	31	oligodendrocytes.188	oligodendrocytes.188	PROPN
fnp-3528	67	32	abca3	abca3	X
fnp-3528	67	33	plays	play	VERB
fnp-3528	67	34	a	a	DET
fnp-3528	67	35	role	role	NOUN
fnp-3528	67	36	in	in	ADP
fnp-3528	67	37	producing	produce	VERB
fnp-3528	67	38	surfactants	surfactant	NOUN
fnp-3528	67	39	in	in	ADP
fnp-3528	67	40	the	the	DET
fnp-3528	67	41	lung	lung	NOUN
fnp-3528	67	42	,	,	PUNCT
fnp-3528	67	43	suggesting	suggest	VERB
fnp-3528	67	44	that	that	SCONJ
fnp-3528	67	45	the	the	DET
fnp-3528	67	46	transporter	transporter	NOUN
fnp-3528	67	47	may	may	AUX
fnp-3528	67	48	also	also	ADV
fnp-3528	67	49	be	be	AUX
fnp-3528	67	50	involved	involve	VERB
fnp-3528	67	51	in	in	ADP
fnp-3528	67	52	lipid	lipid	ADJ
fnp-3528	67	53	metabolism	metabolism	NOUN
fnp-3528	67	54	in	in	ADP
fnp-3528	67	55	the	the	DET
fnp-3528	67	56	brain	brain	NOUN
fnp-3528	67	57	,	,	PUNCT
fnp-3528	67	58	specifically	specifically	ADV
fnp-3528	67	59	phosphatidylcholine	phosphatidylcholine	NOUN
fnp-3528	67	60	and	and	CCONJ
fnp-3528	67	61	phosphatidylglycerol	phosphatidylglycerol	VERB
fnp-3528	67	62	transport	transport	NOUN
fnp-3528	67	63	.	.	PUNCT
fnp-3528	68	1	interestingly	interestingly	ADV
fnp-3528	68	2	,	,	PUNCT
fnp-3528	68	3	phosphatidylcholine	phosphatidylcholine	PROPN
fnp-3528	68	4	has	have	AUX
fnp-3528	68	5	also	also	ADV
fnp-3528	68	6	been	be	AUX
fnp-3528	68	7	discussed	discuss	VERB
fnp-3528	68	8	in	in	ADP
fnp-3528	68	9	the	the	DET
fnp-3528	68	10	context	context	NOUN
fnp-3528	68	11	of	of	ADP
fnp-3528	68	12	ad.189	ad.189	PROPN
fnp-3528	68	13	a	a	DET
fnp-3528	68	14	genetic	genetic	ADJ
fnp-3528	68	15	study	study	NOUN
fnp-3528	68	16	revealed	reveal	VERB
fnp-3528	68	17	that	that	SCONJ
fnp-3528	68	18	mutations	mutation	NOUN
fnp-3528	68	19	in	in	ADP
fnp-3528	68	20	abca3	abca3	PROPN
fnp-3528	68	21	can	can	AUX
fnp-3528	68	22	also	also	ADV
fnp-3528	68	23	cause	cause	VERB
fnp-3528	68	24	cataract	cataract	NOUN
fnp-3528	68	25	-	-	PUNCT
fnp-3528	68	26	microcornea	microcornea	NOUN
fnp-3528	68	27	syndrome	syndrome	NOUN
fnp-3528	68	28	,	,	PUNCT
fnp-3528	68	29	a	a	DET
fnp-3528	68	30	rare	rare	ADJ
fnp-3528	68	31	congenital	congenital	ADJ
fnp-3528	68	32	malformation	malformation	NOUN
fnp-3528	68	33	of	of	ADP
fnp-3528	68	34	the	the	DET
fnp-3528	68	35	eye.141	eye.141	NOUN
fnp-3528	68	36	the	the	DET
fnp-3528	68	37	actual	actual	ADJ
fnp-3528	68	38	implications	implication	NOUN
fnp-3528	68	39	of	of	ADP
fnp-3528	68	40	the	the	DET
fnp-3528	68	41	potential	potential	ADJ
fnp-3528	68	42	connection	connection	NOUN
fnp-3528	68	43	between	between	ADP
fnp-3528	68	44	altered	alter	VERB
fnp-3528	68	45	abca3	abca3	PROPN
fnp-3528	68	46	functionality	functionality	NOUN
fnp-3528	68	47	and	and	CCONJ
fnp-3528	68	48	ad	ad	NOUN
fnp-3528	68	49	need	need	NOUN
fnp-3528	68	50	to	to	PART
fnp-3528	68	51	be	be	AUX
fnp-3528	68	52	addressed	address	VERB
fnp-3528	68	53	in	in	ADP
fnp-3528	68	54	future	future	ADJ
fnp-3528	68	55	studies	study	NOUN
fnp-3528	68	56	.	.	PUNCT
fnp-3528	69	1	abca4	abca4	PROPN
fnp-3528	69	2	abca4	abca4	PROPN
fnp-3528	69	3	is	be	AUX
fnp-3528	69	4	mainly	mainly	ADV
fnp-3528	69	5	expressed	express	VERB
fnp-3528	69	6	in	in	ADP
fnp-3528	69	7	the	the	DET
fnp-3528	69	8	retina	retina	NOUN
fnp-3528	69	9	with	with	ADP
fnp-3528	69	10	very	very	ADV
fnp-3528	69	11	little	little	ADJ
fnp-3528	69	12	presence	presence	NOUN
fnp-3528	69	13	in	in	ADP
fnp-3528	69	14	other	other	ADJ
fnp-3528	69	15	tissues	tissue	NOUN
fnp-3528	69	16	of	of	ADP
fnp-3528	69	17	the	the	DET
fnp-3528	69	18	cns.190	cns.190	NOUN
fnp-3528	69	19	abca4	abca4	PROPN
fnp-3528	69	20	mutation	mutation	NOUN
fnp-3528	69	21	causes	cause	VERB
fnp-3528	69	22	stargardt	stargardt	ADJ
fnp-3528	69	23	disease	disease	NOUN
fnp-3528	69	24	,	,	PUNCT
fnp-3528	69	25	characterized	characterize	VERB
fnp-3528	69	26	by	by	ADP
fnp-3528	69	27	macular	macular	ADJ
fnp-3528	69	28	dystrophy	dystrophy	NOUN
fnp-3528	69	29	,	,	PUNCT
fnp-3528	69	30	retinal	retinal	ADJ
fnp-3528	69	31	alterations	alteration	NOUN
fnp-3528	69	32	,	,	PUNCT
fnp-3528	69	33	and	and	CCONJ
fnp-3528	69	34	lipofuscin	lipofuscin	VERB
fnp-3528	69	35	accumulation.60,61,190,191	accumulation.60,61,190,191	PRON
fnp-3528	69	36	other	other	ADJ
fnp-3528	69	37	retinal	retinal	ADJ
fnp-3528	69	38	diseases	disease	NOUN
fnp-3528	69	39	,	,	PUNCT
fnp-3528	69	40	such	such	ADJ
fnp-3528	69	41	as	as	ADP
fnp-3528	69	42	fundus	fundus	X
fnp-3528	69	43	flavimaculatus	flavimaculatus	NOUN
fnp-3528	69	44	,	,	PUNCT
fnp-3528	69	45	retinitis	retinitis	NOUN
fnp-3528	69	46	pigmentosa	pigmentosa	NOUN
fnp-3528	69	47	,	,	PUNCT
fnp-3528	69	48	or	or	CCONJ
fnp-3528	69	49	cone	cone	NOUN
fnp-3528	69	50	-	-	PUNCT
fnp-3528	69	51	rod	rod	NOUN
fnp-3528	69	52	dystrophy	dystrophy	NOUN
fnp-3528	69	53	,	,	PUNCT
fnp-3528	69	54	have	have	AUX
fnp-3528	69	55	also	also	ADV
fnp-3528	69	56	been	be	AUX
fnp-3528	69	57	associated	associate	VERB
fnp-3528	69	58	with	with	ADP
fnp-3528	69	59	mutations	mutation	NOUN
fnp-3528	69	60	of	of	ADP
fnp-3528	69	61	abca4.55,57,58,192	abca4.55,57,58,192	NOUN
fnp-3528	69	62	abca4	abca4	PROPN
fnp-3528	69	63	is	be	AUX
fnp-3528	69	64	expressed	express	VERB
fnp-3528	69	65	in	in	ADP
fnp-3528	69	66	brain	brain	NOUN
fnp-3528	69	67	capillary	capillary	ADJ
fnp-3528	69	68	endothelial	endothelial	ADJ
fnp-3528	69	69	cells	cell	NOUN
fnp-3528	69	70	,	,	PUNCT
fnp-3528	69	71	as	as	SCONJ
fnp-3528	69	72	well.193	well.193	NOUN
fnp-3528	69	73	however	however	ADV
fnp-3528	69	74	,	,	PUNCT
fnp-3528	69	75	no	no	DET
fnp-3528	69	76	link	link	NOUN
fnp-3528	69	77	between	between	ADP
fnp-3528	69	78	abca4	abca4	PROPN
fnp-3528	69	79	and	and	CCONJ
fnp-3528	69	80	ad	ad	NOUN
fnp-3528	69	81	has	have	AUX
fnp-3528	69	82	been	be	AUX
fnp-3528	69	83	suggested	suggest	VERB
fnp-3528	69	84	to	to	ADP
fnp-3528	69	85	date	date	NOUN
fnp-3528	69	86	.	.	PUNCT
fnp-3528	70	1	abca5	abca5	PROPN
fnp-3528	71	1	abca5	abca5	X
fnp-3528	71	2	is	be	AUX
fnp-3528	71	3	a	a	DET
fnp-3528	71	4	little	little	ADV
fnp-3528	71	5	-	-	PUNCT
fnp-3528	71	6	known	know	VERB
fnp-3528	71	7	member	member	NOUN
fnp-3528	71	8	of	of	ADP
fnp-3528	71	9	the	the	DET
fnp-3528	71	10	abca	abca	NOUN
fnp-3528	71	11	subfamily	subfamily	ADV
fnp-3528	71	12	expressed	express	VERB
fnp-3528	71	13	mainly	mainly	ADV
fnp-3528	71	14	in	in	ADP
fnp-3528	71	15	skeletal	skeletal	ADJ
fnp-3528	71	16	muscle	muscle	NOUN
fnp-3528	71	17	with	with	ADP
fnp-3528	71	18	unknown	unknown	ADJ
fnp-3528	71	19	function	function	NOUN
fnp-3528	71	20	in	in	ADP
fnp-3528	71	21	the	the	DET
fnp-3528	71	22	brain.194	brain.194	PROPN
fnp-3528	71	23	studies	study	NOUN
fnp-3528	71	24	in	in	ADP
fnp-3528	71	25	peripheral	peripheral	ADJ
fnp-3528	71	26	tissues	tissue	NOUN
fnp-3528	71	27	suggest	suggest	VERB
fnp-3528	71	28	that	that	SCONJ
fnp-3528	71	29	the	the	DET
fnp-3528	71	30	function	function	NOUN
fnp-3528	71	31	of	of	ADP
fnp-3528	71	32	abca5	abca5	NOUN
fnp-3528	71	33	is	be	AUX
fnp-3528	71	34	associated	associate	VERB
fnp-3528	71	35	with	with	ADP
fnp-3528	71	36	cellular	cellular	ADJ
fnp-3528	71	37	lipid	lipid	NOUN
fnp-3528	71	38	metabolism.195	metabolism.195	PROPN
fnp-3528	71	39	abca5	abca5	NOUN
fnp-3528	71	40	knock	knock	NOUN
fnp-3528	71	41	-	-	PUNCT
fnp-3528	71	42	out	out	NOUN
fnp-3528	71	43	in	in	ADP
fnp-3528	71	44	mice	mouse	NOUN
fnp-3528	71	45	induced	induce	VERB
fnp-3528	71	46	signs	sign	NOUN
fnp-3528	71	47	of	of	ADP
fnp-3528	71	48	lysosomal	lysosomal	ADJ
fnp-3528	71	49	storage	storage	NOUN
fnp-3528	71	50	disease	disease	NOUN
fnp-3528	71	51	in	in	ADP
fnp-3528	71	52	the	the	DET
fnp-3528	71	53	heart	heart	NOUN
fnp-3528	71	54	and	and	CCONJ
fnp-3528	71	55	the	the	DET
fnp-3528	71	56	thyroid	thyroid	NOUN
fnp-3528	71	57	gland.131	gland.131	NUM
fnp-3528	71	58	in	in	ADP
fnp-3528	71	59	the	the	DET
fnp-3528	71	60	brain	brain	NOUN
fnp-3528	71	61	,	,	PUNCT
fnp-3528	71	62	abca5	abca5	X
fnp-3528	71	63	is	be	AUX
fnp-3528	71	64	expressed	express	VERB
fnp-3528	71	65	in	in	ADP
fnp-3528	71	66	neurons	neuron	NOUN
fnp-3528	71	67	and	and	CCONJ
fnp-3528	71	68	,	,	PUNCT
fnp-3528	71	69	to	to	ADP
fnp-3528	71	70	a	a	DET
fnp-3528	71	71	lesser	less	ADJ
fnp-3528	71	72	extent	extent	NOUN
fnp-3528	71	73	,	,	PUNCT
fnp-3528	71	74	in	in	ADP
fnp-3528	71	75	microglia	microglia	ADJ
fnp-3528	71	76	,	,	PUNCT
fnp-3528	72	1	astrocytes	astrocyte	NOUN
fnp-3528	72	2	,	,	PUNCT
fnp-3528	72	3	and	and	CCONJ
fnp-3528	72	4	oligodendrocytes.195	oligodendrocytes.195	NOUN
fnp-3528	72	5	fu	fu	NOUN
fnp-3528	72	6	et	et	PROPN
fnp-3528	72	7	al	al	PROPN
fnp-3528	72	8	.	.	PROPN
fnp-3528	72	9	showed	show	VERB
fnp-3528	72	10	that	that	SCONJ
fnp-3528	72	11	abca5	abca5	NOUN
fnp-3528	72	12	stimulated	stimulate	VERB
fnp-3528	72	13	cholesterol	cholesterol	NOUN
fnp-3528	72	14	efflux	efflux	NOUN
fnp-3528	72	15	in	in	ADP
fnp-3528	72	16	neurons	neuron	NOUN
fnp-3528	72	17	and	and	CCONJ
fnp-3528	72	18	induced	induce	VERB
fnp-3528	72	19	a	a	DET
fnp-3528	72	20	decrease	decrease	NOUN
fnp-3528	72	21	in	in	ADP
fnp-3528	72	22	aβ	aβ	PRON
fnp-3528	72	23	production	production	NOUN
fnp-3528	72	24	probably	probably	ADV
fnp-3528	72	25	affecting	affect	VERB
fnp-3528	72	26	app	app	NOUN
fnp-3528	72	27	processing	processing	NOUN
fnp-3528	72	28	but	but	CCONJ
fnp-3528	72	29	not	not	PART
fnp-3528	72	30	its	its	PRON
fnp-3528	72	31	expression.195	expression.195	ADJ
fnp-3528	72	32	abca6	abca6	PROPN
fnp-3528	72	33	abca6	abca6	PROPN
fnp-3528	72	34	is	be	AUX
fnp-3528	72	35	ubiquitously	ubiquitously	ADV
fnp-3528	72	36	expressed	express	VERB
fnp-3528	72	37	with	with	ADP
fnp-3528	72	38	high	high	ADJ
fnp-3528	72	39	levels	level	NOUN
fnp-3528	72	40	in	in	ADP
fnp-3528	72	41	liver	liver	NOUN
fnp-3528	72	42	,	,	PUNCT
fnp-3528	72	43	lung	lung	NOUN
fnp-3528	72	44	,	,	PUNCT
fnp-3528	72	45	heart	heart	NOUN
fnp-3528	72	46	,	,	PUNCT
fnp-3528	72	47	brain	brain	NOUN
fnp-3528	72	48	,	,	PUNCT
fnp-3528	72	49	and	and	CCONJ
fnp-3528	72	50	ovaries	ovary	NOUN
fnp-3528	72	51	.	.	PUNCT
fnp-3528	73	1	this	this	DET
fnp-3528	73	2	transporter	transporter	NOUN
fnp-3528	73	3	is	be	AUX
fnp-3528	73	4	probably	probably	ADV
fnp-3528	73	5	involved	involve	VERB
fnp-3528	73	6	in	in	ADP
fnp-3528	73	7	macrophage	macrophage	ADJ
fnp-3528	73	8	lipid	lipid	NOUN
fnp-3528	73	9	homeostasis	homeostasis	NOUN
fnp-3528	73	10	as	as	SCONJ
fnp-3528	73	11	it	it	PRON
fnp-3528	73	12	is	be	AUX
fnp-3528	73	13	upregulated	upregulate	VERB
fnp-3528	73	14	during	during	ADP
fnp-3528	73	15	macrophage	macrophage	ADJ
fnp-3528	73	16	differentiation	differentiation	NOUN
fnp-3528	73	17	and	and	CCONJ
fnp-3528	73	18	is	be	AUX
fnp-3528	73	19	responsive	responsive	ADJ
fnp-3528	73	20	to	to	ADP
fnp-3528	73	21	cholesterol	cholesterol	NOUN
fnp-3528	73	22	treatment.196	treatment.196	NOUN
fnp-3528	73	23	although	although	SCONJ
fnp-3528	73	24	certain	certain	ADJ
fnp-3528	73	25	missense	missense	NOUN
fnp-3528	73	26	variants	variant	NOUN
fnp-3528	73	27	of	of	ADP
fnp-3528	73	28	abca6	abca6	PROPN
fnp-3528	73	29	have	have	AUX
fnp-3528	73	30	been	be	AUX
fnp-3528	73	31	correlated	correlate	VERB
fnp-3528	73	32	with	with	ADP
fnp-3528	73	33	blood	blood	NOUN
fnp-3528	73	34	cholesterol	cholesterol	NOUN
fnp-3528	74	1	levels,197	levels,197	PROPN
fnp-3528	75	1	no	no	DET
fnp-3528	75	2	link	link	NOUN
fnp-3528	75	3	between	between	ADP
fnp-3528	75	4	abca6	abca6	PROPN
fnp-3528	75	5	and	and	CCONJ
fnp-3528	75	6	ad	ad	NOUN
fnp-3528	75	7	has	have	AUX
fnp-3528	75	8	yet	yet	ADV
fnp-3528	75	9	been	be	AUX
fnp-3528	75	10	found	find	VERB
fnp-3528	75	11	.	.	PUNCT
fnp-3528	76	1	abca7	abca7	PROPN
fnp-3528	76	2	abca7	abca7	PROPN
fnp-3528	76	3	was	be	AUX
fnp-3528	76	4	first	first	ADV
fnp-3528	76	5	identified	identify	VERB
fnp-3528	76	6	in	in	ADP
fnp-3528	76	7	the	the	DET
fnp-3528	76	8	year	year	NOUN
fnp-3528	76	9	2000	2000	NUM
fnp-3528	76	10	,	,	PUNCT
fnp-3528	76	11	and	and	CCONJ
fnp-3528	76	12	is	be	AUX
fnp-3528	76	13	located	locate	VERB
fnp-3528	76	14	on	on	ADP
fnp-3528	76	15	human	human	ADJ
fnp-3528	76	16	chromosome	chromosome	NOUN
fnp-3528	76	17	19.198	19.198	NUM
fnp-3528	76	18	-	-	SYM
fnp-3528	76	19	200	200	NUM
fnp-3528	76	20	analysis	analysis	NOUN
fnp-3528	76	21	of	of	ADP
fnp-3528	76	22	abca7	abca7	PROPN
fnp-3528	76	23	mrna	mrna	PROPN
fnp-3528	76	24	expression	expression	NOUN
fnp-3528	76	25	levels	level	NOUN
fnp-3528	76	26	has	have	AUX
fnp-3528	76	27	shown	show	VERB
fnp-3528	76	28	that	that	SCONJ
fnp-3528	76	29	this	this	DET
fnp-3528	76	30	transporter	transporter	NOUN
fnp-3528	76	31	is	be	AUX
fnp-3528	76	32	mainly	mainly	ADV
fnp-3528	76	33	confined	confine	VERB
fnp-3528	76	34	to	to	ADP
fnp-3528	76	35	the	the	DET
fnp-3528	76	36	brain	brain	NOUN
fnp-3528	76	37	and	and	CCONJ
fnp-3528	76	38	the	the	DET
fnp-3528	76	39	immune	immune	ADJ
fnp-3528	76	40	system.3	system.3	NOUN
fnp-3528	76	41	due	due	ADP
fnp-3528	76	42	to	to	ADP
fnp-3528	76	43	its	its	PRON
fnp-3528	76	44	high	high	ADJ
fnp-3528	76	45	homology	homology	NOUN
fnp-3528	76	46	to	to	ADP
fnp-3528	76	47	abca1	abca1	PROPN
fnp-3528	76	48	(	(	PUNCT
fnp-3528	76	49	54%),200	54%),200	NUM
fnp-3528	76	50	abca7	abca7	NOUN
fnp-3528	76	51	was	be	AUX
fnp-3528	76	52	first	first	ADV
fnp-3528	76	53	hypothesized	hypothesize	VERB
fnp-3528	76	54	to	to	PART
fnp-3528	76	55	play	play	VERB
fnp-3528	76	56	an	an	DET
fnp-3528	76	57	important	important	ADJ
fnp-3528	76	58	role	role	NOUN
fnp-3528	76	59	in	in	ADP
fnp-3528	76	60	lipid	lipid	NOUN
fnp-3528	76	61	trafficking	trafficking	NOUN
fnp-3528	76	62	,	,	PUNCT
fnp-3528	76	63	mediating	mediate	VERB
fnp-3528	76	64	cholesterol	cholesterol	NOUN
fnp-3528	76	65	and	and	CCONJ
fnp-3528	76	66	phospholipid	phospholipid	NOUN
fnp-3528	76	67	efflux	efflux	NOUN
fnp-3528	76	68	.	.	PUNCT
fnp-3528	77	1	abca7	abca7	PROPN
fnp-3528	77	2	actively	actively	ADV
fnp-3528	77	3	transports	transport	VERB
fnp-3528	77	4	phosphatidylcholine	phosphatidylcholine	NOUN
fnp-3528	77	5	,	,	PUNCT
fnp-3528	77	6	phosphatidylserine	phosphatidylserine	NOUN
fnp-3528	77	7	,	,	PUNCT
fnp-3528	77	8	and	and	CCONJ
fnp-3528	77	9	sphingomyelin	sphingomyelin	NOUN
fnp-3528	77	10	from	from	ADP
fnp-3528	77	11	the	the	DET
fnp-3528	77	12	cytoplasm	cytoplasm	NOUN
fnp-3528	77	13	to	to	ADP
fnp-3528	77	14	the	the	DET
fnp-3528	77	15	exocytoplasmic	exocytoplasmic	ADJ
fnp-3528	77	16	leaflet	leaflet	NOUN
fnp-3528	77	17	of	of	ADP
fnp-3528	77	18	membranes.198,199,201	membranes.198,199,201	VERB
fnp-3528	77	19	however	however	ADV
fnp-3528	77	20	,	,	PUNCT
fnp-3528	77	21	in	in	ADP
fnp-3528	77	22	contrast	contrast	NOUN
fnp-3528	77	23	to	to	ADP
fnp-3528	77	24	abca1	abca1	NOUN
fnp-3528	77	25	,	,	PUNCT
fnp-3528	77	26	abca7	abca7	PROPN
fnp-3528	77	27	generates	generate	VERB
fnp-3528	77	28	only	only	ADV
fnp-3528	77	29	small	small	ADJ
fnp-3528	77	30	hdl	hdl	PROPN
fnp-3528	78	1	particles.202	particles.202	PROPN
fnp-3528	78	2	recent	recent	ADJ
fnp-3528	78	3	research	research	NOUN
fnp-3528	78	4	has	have	AUX
fnp-3528	78	5	shown	show	VERB
fnp-3528	78	6	that	that	SCONJ
fnp-3528	78	7	lipid	lipid	NOUN
fnp-3528	78	8	trafficking	trafficking	NOUN
fnp-3528	78	9	by	by	ADP
fnp-3528	78	10	abca7	abca7	PROPN
fnp-3528	78	11	plays	play	VERB
fnp-3528	78	12	a	a	DET
fnp-3528	78	13	secondary	secondary	ADJ
fnp-3528	78	14	role	role	NOUN
fnp-3528	78	15	.	.	PUNCT
fnp-3528	79	1	studies	study	NOUN
fnp-3528	79	2	in	in	ADP
fnp-3528	79	3	abca7	abca7	PROPN
fnp-3528	79	4	knock	knock	VERB
fnp-3528	79	5	-	-	PUNCT
fnp-3528	79	6	out	out	ADP
fnp-3528	79	7	models	model	NOUN
fnp-3528	79	8	have	have	AUX
fnp-3528	79	9	demonstrated	demonstrate	VERB
fnp-3528	79	10	that	that	SCONJ
fnp-3528	79	11	abca7	abca7	PROPN
fnp-3528	79	12	is	be	AUX
fnp-3528	79	13	involved	involve	VERB
fnp-3528	79	14	in	in	ADP
fnp-3528	79	15	the	the	DET
fnp-3528	79	16	phagocytotic	phagocytotic	ADJ
fnp-3528	79	17	activity	activity	NOUN
fnp-3528	79	18	of	of	ADP
fnp-3528	79	19	macrophages	macrophage	NOUN
fnp-3528	79	20	and	and	CCONJ
fnp-3528	79	21	fibroblasts198,203	fibroblasts198,203	NOUN
fnp-3528	79	22	-	-	SYM
fnp-3528	79	23	205	205	NUM
fnp-3528	79	24	but	but	CCONJ
fnp-3528	79	25	not	not	PART
fnp-3528	79	26	in	in	ADP
fnp-3528	79	27	cell	cell	NOUN
fnp-3528	79	28	cholesterol	cholesterol	NOUN
fnp-3528	79	29	release.206	release.206	NOUN
fnp-3528	79	30	-	-	PUNCT
fnp-3528	79	31	208	208	NUM
fnp-3528	79	32	in	in	ADP
fnp-3528	79	33	2011	2011	NUM
fnp-3528	79	34	,	,	PUNCT
fnp-3528	79	35	hollingworth	hollingworth	NOUN
fnp-3528	79	36	et	et	PROPN
fnp-3528	79	37	al	al	PROPN
fnp-3528	79	38	.	.	PROPN
fnp-3528	79	39	identified	identify	VERB
fnp-3528	79	40	the	the	DET
fnp-3528	79	41	abca7	abca7	PROPN
fnp-3528	79	42	gene	gene	NOUN
fnp-3528	79	43	as	as	ADP
fnp-3528	79	44	an	an	DET
fnp-3528	79	45	ad	ad	NOUN
fnp-3528	79	46	risk	risk	NOUN
fnp-3528	79	47	locus.198,209	locus.198,209	NOUN
fnp-3528	79	48	in	in	ADP
fnp-3528	79	49	multiple	multiple	ADJ
fnp-3528	79	50	studies	study	NOUN
fnp-3528	79	51	,	,	PUNCT
fnp-3528	79	52	variants	variant	NOUN
fnp-3528	79	53	of	of	ADP
fnp-3528	79	54	abca7	abca7	PROPN
fnp-3528	79	55	have	have	AUX
fnp-3528	79	56	been	be	AUX
fnp-3528	79	57	associated	associate	VERB
fnp-3528	79	58	with	with	ADP
fnp-3528	79	59	an	an	DET
fnp-3528	79	60	increased	increase	VERB
fnp-3528	79	61	risk	risk	NOUN
fnp-3528	79	62	of	of	ADP
fnp-3528	79	63	developing	develop	VERB
fnp-3528	79	64	ad.198,210	ad.198,210	NOUN
fnp-3528	79	65	-	-	PUNCT
fnp-3528	79	66	212	212	NUM
fnp-3528	79	67	in	in	ADP
fnp-3528	79	68	2015	2015	NUM
fnp-3528	79	69	,	,	PUNCT
fnp-3528	79	70	steinberg	steinberg	PROPN
fnp-3528	79	71	et	et	PROPN
fnp-3528	79	72	al	al	PROPN
fnp-3528	79	73	.	.	PROPN
fnp-3528	79	74	reported	report	VERB
fnp-3528	79	75	that	that	SCONJ
fnp-3528	79	76	rare	rare	ADJ
fnp-3528	79	77	loss	loss	NOUN
fnp-3528	79	78	-	-	PUNCT
fnp-3528	79	79	of	of	ADP
fnp-3528	79	80	-	-	PUNCT
fnp-3528	79	81	function	function	NOUN
fnp-3528	79	82	variants	variant	NOUN
fnp-3528	79	83	of	of	ADP
fnp-3528	79	84	abca7	abca7	PROPN
fnp-3528	79	85	confer	confer	VERB
fnp-3528	79	86	a	a	DET
fnp-3528	79	87	risk	risk	NOUN
fnp-3528	79	88	of	of	ADP
fnp-3528	79	89	ad	ad	NOUN
fnp-3528	79	90	in	in	ADP
fnp-3528	79	91	icelanders	icelanders	PROPN
fnp-3528	79	92	(	(	PUNCT
fnp-3528	79	93	odds	odd	NOUN
fnp-3528	79	94	ratio	ratio	NOUN
fnp-3528	79	95	:	:	PUNCT
fnp-3528	79	96	2.12	2.12	NUM
fnp-3528	79	97	;	;	PUNCT
fnp-3528	79	98	p	p	NOUN
fnp-3528	79	99	=	=	NOUN
fnp-3528	79	100	2.2	2.2	NUM
fnp-3528	79	101	∙	∙	PROPN
fnp-3528	79	102	10	10	NUM
fnp-3528	79	103	-	-	SYM
fnp-3528	79	104	13	13	NUM
fnp-3528	79	105	)	)	PUNCT
fnp-3528	79	106	,	,	PUNCT
fnp-3528	79	107	and	and	CCONJ
fnp-3528	79	108	found	find	VERB
fnp-3528	79	109	a	a	DET
fnp-3528	79	110	similar	similar	ADJ
fnp-3528	79	111	association	association	NOUN
fnp-3528	79	112	in	in	ADP
fnp-3528	79	113	study	study	NOUN
fnp-3528	79	114	groups	group	NOUN
fnp-3528	79	115	from	from	ADP
fnp-3528	79	116	europe	europe	PROPN
fnp-3528	79	117	and	and	CCONJ
fnp-3528	79	118	the	the	DET
fnp-3528	79	119	united	united	PROPN
fnp-3528	79	120	states	states	PROPN
fnp-3528	79	121	(	(	PUNCT
fnp-3528	79	122	combined	combine	VERB
fnp-3528	79	123	odds	odd	NOUN
fnp-3528	79	124	ratio	ratio	NOUN
fnp-3528	79	125	:	:	PUNCT
fnp-3528	79	126	2.03	2.03	NUM
fnp-3528	79	127	;	;	PUNCT
fnp-3528	79	128	p	p	NOUN
fnp-3528	79	129	=	=	NOUN
fnp-3528	79	130	6.8	6.8	NUM
fnp-3528	79	131	∙	∙	PROPN
fnp-3528	79	132	10	10	NUM
fnp-3528	79	133	-	-	SYM
fnp-3528	79	134	15).213	15).213	NUM
fnp-3528	79	135	in	in	ADP
fnp-3528	79	136	particular	particular	ADJ
fnp-3528	79	137	,	,	PUNCT
fnp-3528	79	138	the	the	DET
fnp-3528	79	139	rare	rare	ADJ
fnp-3528	79	140	ad	ad	NOUN
fnp-3528	79	141	-	-	PUNCT
fnp-3528	79	142	related	relate	VERB
fnp-3528	79	143	polymorphism	polymorphism	NOUN
fnp-3528	79	144	rs200538373	rs200538373	NOUN
fnp-3528	79	145	was	be	AUX
fnp-3528	79	146	associated	associate	VERB
fnp-3528	79	147	with	with	ADP
fnp-3528	79	148	an	an	DET
fnp-3528	79	149	ad	ad	NOUN
fnp-3528	79	150	risk	risk	NOUN
fnp-3528	79	151	odds	odd	VERB
fnp-3528	79	152	ratio	ratio	NOUN
fnp-3528	79	153	of	of	ADP
fnp-3528	79	154	1.9.210	1.9.210	PROPN
fnp-3528	79	155	these	these	DET
fnp-3528	79	156	studies	study	NOUN
fnp-3528	79	157	suggest	suggest	VERB
fnp-3528	79	158	that	that	SCONJ
fnp-3528	79	159	reduced	reduced	ADJ
fnp-3528	79	160	levels	level	NOUN
fnp-3528	79	161	of	of	ADP
fnp-3528	79	162	abca7	abca7	PROPN
fnp-3528	79	163	may	may	AUX
fnp-3528	79	164	increase	increase	VERB
fnp-3528	79	165	the	the	DET
fnp-3528	79	166	risk	risk	NOUN
fnp-3528	79	167	of	of	ADP
fnp-3528	79	168	ad	ad	NOUN
fnp-3528	79	169	.	.	PUNCT
fnp-3528	80	1	nonetheless	nonetheless	ADV
fnp-3528	80	2	,	,	PUNCT
fnp-3528	80	3	it	it	PRON
fnp-3528	80	4	is	be	AUX
fnp-3528	80	5	not	not	PART
fnp-3528	80	6	clear	clear	ADJ
fnp-3528	80	7	how	how	SCONJ
fnp-3528	80	8	these	these	DET
fnp-3528	80	9	polymorphisms	polymorphism	NOUN
fnp-3528	80	10	affect	affect	VERB
fnp-3528	80	11	abca7	abca7	PROPN
fnp-3528	80	12	function	function	NOUN
fnp-3528	80	13	and	and	CCONJ
fnp-3528	80	14	contribute	contribute	VERB
fnp-3528	80	15	to	to	ADP
fnp-3528	80	16	ad	ad	NOUN
fnp-3528	80	17	progression	progression	NOUN
fnp-3528	80	18	.	.	PUNCT
fnp-3528	81	1	increased	increase	VERB
fnp-3528	81	2	levels	level	NOUN
fnp-3528	81	3	of	of	ADP
fnp-3528	81	4	abca7	abca7	NOUN
fnp-3528	81	5	expression	expression	NOUN
fnp-3528	81	6	were	be	AUX
fnp-3528	81	7	described	describe	VERB
fnp-3528	81	8	in	in	ADP
fnp-3528	81	9	ad	ad	NOUN
fnp-3528	81	10	patients	patient	NOUN
fnp-3528	81	11	and	and	CCONJ
fnp-3528	81	12	were	be	AUX
fnp-3528	81	13	also	also	ADV
fnp-3528	81	14	positively	positively	ADV
fnp-3528	81	15	correlated	correlate	VERB
fnp-3528	81	16	with	with	ADP
fnp-3528	81	17	cognitive	cognitive	ADJ
fnp-3528	81	18	decline.198,211	decline.198,211	NOUN
fnp-3528	81	19	this	this	DET
fnp-3528	81	20	finding	finding	NOUN
fnp-3528	81	21	is	be	AUX
fnp-3528	81	22	consistent	consistent	ADJ
fnp-3528	81	23	with	with	ADP
fnp-3528	81	24	abca7	abca7	PROPN
fnp-3528	81	25	mrna	mrna	PROPN
fnp-3528	81	26	transcription	transcription	NOUN
fnp-3528	81	27	levels	level	NOUN
fnp-3528	81	28	in	in	ADP
fnp-3528	81	29	j20	j20	PROPN
fnp-3528	81	30	mice.123	mice.123	PROPN
fnp-3528	81	31	the	the	DET
fnp-3528	81	32	increase	increase	NOUN
fnp-3528	81	33	of	of	ADP
fnp-3528	81	34	abca7	abca7	NOUN
fnp-3528	81	35	may	may	AUX
fnp-3528	81	36	be	be	AUX
fnp-3528	81	37	a	a	DET
fnp-3528	81	38	compensatory	compensatory	ADJ
fnp-3528	81	39	defense	defense	NOUN
fnp-3528	81	40	mechanism	mechanism	NOUN
fnp-3528	81	41	that	that	PRON
fnp-3528	81	42	is	be	AUX
fnp-3528	81	43	insufficient	insufficient	ADJ
fnp-3528	81	44	to	to	PART
fnp-3528	81	45	stop	stop	VERB
fnp-3528	81	46	disease	disease	NOUN
fnp-3528	81	47	progression	progression	NOUN
fnp-3528	81	48	.	.	PUNCT
fnp-3528	82	1	furthermore	furthermore	ADV
fnp-3528	82	2	,	,	PUNCT
fnp-3528	82	3	the	the	DET
fnp-3528	82	4	rs3764650	rs3764650	PROPN
fnp-3528	82	5	g	g	NOUN
fnp-3528	82	6	allele	allele	NOUN
fnp-3528	82	7	has	have	AUX
fnp-3528	82	8	been	be	AUX
fnp-3528	82	9	associated	associate	VERB
fnp-3528	82	10	with	with	ADP
fnp-3528	82	11	increased	increase	VERB
fnp-3528	82	12	neuritic	neuritic	ADJ
fnp-3528	82	13	plaques	plaque	NOUN
fnp-3528	82	14	in	in	ADP
fnp-3528	82	15	human	human	ADJ
fnp-3528	82	16	patients198,214	patients198,214	NOUN
fnp-3528	82	17	and	and	CCONJ
fnp-3528	82	18	a	a	DET
fnp-3528	82	19	limitation	limitation	NOUN
fnp-3528	82	20	of	of	ADP
fnp-3528	82	21	the	the	DET
fnp-3528	82	22	neuroprotective	neuroprotective	ADJ
fnp-3528	82	23	effects	effect	NOUN
fnp-3528	82	24	of	of	ADP
fnp-3528	82	25	exercise	exercise	NOUN
fnp-3528	82	26	intervention.215	intervention.215	NOUN
fnp-3528	82	27	these	these	DET
fnp-3528	82	28	studies	study	NOUN
fnp-3528	82	29	support	support	VERB
fnp-3528	82	30	a	a	DET
fnp-3528	82	31	potential	potential	ADJ
fnp-3528	82	32	protective	protective	ADJ
fnp-3528	82	33	role	role	NOUN
fnp-3528	82	34	of	of	ADP
fnp-3528	82	35	abca7	abca7	NOUN
fnp-3528	82	36	in	in	ADP
fnp-3528	82	37	ad	ad	NOUN
fnp-3528	82	38	.	.	PUNCT
fnp-3528	83	1	to	to	ADP
fnp-3528	83	2	date	date	NOUN
fnp-3528	83	3	,	,	PUNCT
fnp-3528	83	4	three	three	NUM
fnp-3528	83	5	potential	potential	ADJ
fnp-3528	83	6	roles	role	NOUN
fnp-3528	83	7	have	have	AUX
fnp-3528	83	8	been	be	AUX
fnp-3528	83	9	identified	identify	VERB
fnp-3528	83	10	for	for	ADP
fnp-3528	83	11	abca7	abca7	PROPN
fnp-3528	83	12	contribution	contribution	NOUN
fnp-3528	83	13	to	to	ADP
fnp-3528	83	14	ad	ad	NOUN
fnp-3528	83	15	:	:	PUNCT
fnp-3528	83	16	app	app	NOUN
fnp-3528	83	17	processing	processing	NOUN
fnp-3528	83	18	,	,	PUNCT
fnp-3528	83	19	immune	immune	ADJ
fnp-3528	83	20	response	response	NOUN
fnp-3528	83	21	,	,	PUNCT
fnp-3528	83	22	and	and	CCONJ
fnp-3528	83	23	lipid	lipid	ADJ
fnp-3528	83	24	metabolism	metabolism	NOUN
fnp-3528	83	25	.	.	PUNCT
fnp-3528	84	1	chan	chan	PROPN
fnp-3528	84	2	et	et	PROPN
fnp-3528	84	3	al	al	PROPN
fnp-3528	84	4	.	.	PROPN
fnp-3528	84	5	proposed	propose	VERB
fnp-3528	84	6	an	an	DET
fnp-3528	84	7	inhibitory	inhibitory	ADJ
fnp-3528	84	8	effect	effect	NOUN
fnp-3528	84	9	of	of	ADP
fnp-3528	84	10	abca7	abca7	PROPN
fnp-3528	84	11	on	on	ADP
fnp-3528	84	12	aβ	aβ	ADJ
fnp-3528	84	13	deposition	deposition	NOUN
fnp-3528	84	14	after	after	ADP
fnp-3528	84	15	showing	show	VERB
fnp-3528	84	16	in	in	ADP
fnp-3528	84	17	vitro	vitro	X
fnp-3528	84	18	inhibition	inhibition	NOUN
fnp-3528	84	19	of	of	ADP
fnp-3528	84	20	aβ	aβ	NOUN
fnp-3528	84	21	production	production	NOUN
fnp-3528	84	22	independent	independent	ADJ
fnp-3528	84	23	of	of	ADP
fnp-3528	84	24	β	β	NOUN
fnp-3528	84	25	-	-	NOUN
fnp-3528	84	26	secretase	secretase	ADJ
fnp-3528	84	27	activity.120	activity.120	ADJ
fnp-3528	84	28	other	other	ADJ
fnp-3528	84	29	authors	author	NOUN
fnp-3528	84	30	proposed	propose	VERB
fnp-3528	84	31	that	that	SCONJ
fnp-3528	84	32	abca7	abca7	PROPN
fnp-3528	84	33	is	be	AUX
fnp-3528	84	34	not	not	PART
fnp-3528	84	35	directly	directly	ADV
fnp-3528	84	36	linked	link	VERB
fnp-3528	84	37	to	to	ADP
fnp-3528	84	38	aβ	aβ	NOUN
fnp-3528	84	39	production	production	NOUN
fnp-3528	84	40	,	,	PUNCT
fnp-3528	84	41	but	but	CCONJ
fnp-3528	84	42	rather	rather	ADV
fnp-3528	84	43	through	through	ADP
fnp-3528	84	44	lipid	lipid	ADJ
fnp-3528	84	45	metabolism	metabolism	NOUN
fnp-3528	84	46	as	as	SCONJ
fnp-3528	84	47	abca7	abca7	PROPN
fnp-3528	84	48	mediates	mediate	VERB
fnp-3528	84	49	the	the	DET
fnp-3528	84	50	transport	transport	NOUN
fnp-3528	84	51	of	of	ADP
fnp-3528	84	52	lipids	lipid	NOUN
fnp-3528	84	53	across	across	ADP
fnp-3528	84	54	the	the	DET
fnp-3528	84	55	bbb	bbb	NOUN
fnp-3528	84	56	and	and	CCONJ
fnp-3528	84	57	abca7	abca7	PROPN
fnp-3528	84	58	loss	loss	NOUN
fnp-3528	84	59	of	of	ADP
fnp-3528	84	60	function	function	NOUN
fnp-3528	84	61	may	may	AUX
fnp-3528	84	62	alter	alter	VERB
fnp-3528	84	63	cholesterol	cholesterol	NOUN
fnp-3528	84	64	transport	transport	NOUN
fnp-3528	84	65	by	by	ADP
fnp-3528	84	66	decreasing	decrease	VERB
fnp-3528	84	67	apoe	apoe	ADJ
fnp-3528	84	68	secretion	secretion	NOUN
fnp-3528	84	69	and	and	CCONJ
fnp-3528	84	70	abca1	abca1	NOUN
fnp-3528	84	71	expression	expression	NOUN
fnp-3528	84	72	.	.	PUNCT
fnp-3528	85	1	this	this	DET
fnp-3528	85	2	alteration	alteration	NOUN
fnp-3528	85	3	in	in	ADP
fnp-3528	85	4	cholesterol	cholesterol	NOUN
fnp-3528	85	5	metabolism	metabolism	NOUN
fnp-3528	85	6	can	can	AUX
fnp-3528	85	7	also	also	ADV
fnp-3528	85	8	contribute	contribute	VERB
fnp-3528	85	9	to	to	ADP
fnp-3528	85	10	ad	ad	NOUN
fnp-3528	85	11	development.216	development.216	VERB
fnp-3528	85	12	however	however	ADV
fnp-3528	85	13	,	,	PUNCT
fnp-3528	85	14	abca7	abca7	PROPN
fnp-3528	85	15	knock	knock	NOUN
fnp-3528	85	16	-	-	PUNCT
fnp-3528	85	17	out	out	NOUN
fnp-3528	85	18	induced	induce	VERB
fnp-3528	85	19	an	an	DET
fnp-3528	85	20	increase	increase	NOUN
fnp-3528	85	21	of	of	ADP
fnp-3528	85	22	aβ	aβ	PRON
fnp-3528	85	23	load	load	NOUN
fnp-3528	85	24	with	with	ADP
fnp-3528	85	25	no	no	DET
fnp-3528	85	26	difference	difference	NOUN
fnp-3528	85	27	in	in	ADP
fnp-3528	85	28	clearance	clearance	NOUN
fnp-3528	85	29	rate	rate	NOUN
fnp-3528	85	30	and	and	CCONJ
fnp-3528	85	31	an	an	DET
fnp-3528	85	32	increase	increase	NOUN
fnp-3528	85	33	of	of	ADP
fnp-3528	85	34	β	β	NOUN
fnp-3528	85	35	-	-	ADJ
fnp-3528	85	36	secretase	secretase	ADJ
fnp-3528	85	37	expression	expression	NOUN
fnp-3528	85	38	.	.	PUNCT
fnp-3528	86	1	on	on	ADP
fnp-3528	86	2	the	the	DET
fnp-3528	86	3	other	other	ADJ
fnp-3528	86	4	hand	hand	NOUN
fnp-3528	86	5	,	,	PUNCT
fnp-3528	86	6	abca7	abca7	NOUN
fnp-3528	86	7	overexpression	overexpression	NOUN
fnp-3528	86	8	led	lead	VERB
fnp-3528	86	9	to	to	AUX
fnp-3528	86	10	diminished	diminish	VERB
fnp-3528	86	11	aβ	aβ	PRON
fnp-3528	86	12	production	production	NOUN
fnp-3528	86	13	and	and	CCONJ
fnp-3528	86	14	improved	improved	ADJ
fnp-3528	86	15	cognitive	cognitive	ADJ
fnp-3528	86	16	function.217,218	function.217,218	NOUN
fnp-3528	86	17	nevertheless	nevertheless	ADV
fnp-3528	86	18	,	,	PUNCT
fnp-3528	86	19	abca7	abca7	PROPN
fnp-3528	86	20	is	be	AUX
fnp-3528	86	21	highly	highly	ADV
fnp-3528	86	22	expressed	express	VERB
fnp-3528	86	23	in	in	ADP
fnp-3528	86	24	phagocytic	phagocytic	ADJ
fnp-3528	86	25	cells	cell	NOUN
fnp-3528	86	26	,	,	PUNCT
fnp-3528	86	27	including	include	VERB
fnp-3528	86	28	macrophages	macrophage	NOUN
fnp-3528	86	29	and	and	CCONJ
fnp-3528	86	30	microglia	microglia	ADJ
fnp-3528	86	31	,	,	PUNCT
fnp-3528	86	32	suggesting	suggest	VERB
fnp-3528	86	33	a	a	DET
fnp-3528	86	34	role	role	NOUN
fnp-3528	86	35	of	of	ADP
fnp-3528	86	36	the	the	DET
fnp-3528	86	37	transporter	transporter	NOUN
fnp-3528	86	38	in	in	ADP
fnp-3528	86	39	phagocytosis.188,198	phagocytosis.188,198	NOUN
fnp-3528	86	40	phagocytosis	phagocytosis	NOUN
fnp-3528	86	41	is	be	AUX
fnp-3528	86	42	crucial	crucial	ADJ
fnp-3528	86	43	to	to	PART
fnp-3528	86	44	maintain	maintain	VERB
fnp-3528	86	45	brain	brain	NOUN
fnp-3528	86	46	homeostasis	homeostasis	NOUN
fnp-3528	86	47	.	.	PUNCT
fnp-3528	87	1	indeed	indeed	ADV
fnp-3528	87	2	,	,	PUNCT
fnp-3528	87	3	ineffective	ineffective	ADJ
fnp-3528	87	4	phagocytosis	phagocytosis	NOUN
fnp-3528	87	5	may	may	AUX
fnp-3528	87	6	induce	induce	VERB
fnp-3528	87	7	neuroinflammation	neuroinflammation	NOUN
fnp-3528	87	8	,	,	PUNCT
fnp-3528	87	9	which	which	PRON
fnp-3528	87	10	is	be	AUX
fnp-3528	87	11	a	a	DET
fnp-3528	87	12	risk	risk	NOUN
fnp-3528	87	13	factor	factor	NOUN
fnp-3528	87	14	in	in	ADP
fnp-3528	87	15	ad	ad	NOUN
fnp-3528	87	16	.	.	PUNCT
fnp-3528	88	1	in	in	ADP
fnp-3528	88	2	addition	addition	NOUN
fnp-3528	88	3	,	,	PUNCT
fnp-3528	88	4	microglial	microglial	ADJ
fnp-3528	88	5	cells	cell	NOUN
fnp-3528	88	6	are	be	AUX
fnp-3528	88	7	involved	involve	VERB
fnp-3528	88	8	in	in	ADP
fnp-3528	88	9	phagocytosis	phagocytosis	NOUN
fnp-3528	88	10	and	and	CCONJ
fnp-3528	88	11	degradation	degradation	NOUN
fnp-3528	88	12	of	of	ADP
fnp-3528	88	13	aβ	aβ	NOUN
fnp-3528	88	14	.	.	PUNCT
fnp-3528	89	1	thus	thus	ADV
fnp-3528	89	2	,	,	PUNCT
fnp-3528	89	3	an	an	DET
fnp-3528	89	4	involvement	involvement	NOUN
fnp-3528	89	5	of	of	ADP
fnp-3528	89	6	abca7	abca7	PROPN
fnp-3528	89	7	in	in	ADP
fnp-3528	89	8	microglial	microglial	ADJ
fnp-3528	89	9	phagocytosis	phagocytosis	NOUN
fnp-3528	89	10	of	of	ADP
fnp-3528	89	11	aβ	aβ	NOUN
fnp-3528	89	12	may	may	AUX
fnp-3528	89	13	explain	explain	VERB
fnp-3528	89	14	the	the	DET
fnp-3528	89	15	contribution	contribution	NOUN
fnp-3528	89	16	of	of	ADP
fnp-3528	89	17	this	this	DET
fnp-3528	89	18	transporter	transporter	NOUN
fnp-3528	89	19	to	to	ADP
fnp-3528	89	20	ad	ad	NOUN
fnp-3528	89	21	pathogenesis	pathogenesis	NOUN
fnp-3528	89	22	.	.	PUNCT
fnp-3528	90	1	in	in	ADP
fnp-3528	90	2	ad	ad	NOUN
fnp-3528	90	3	patients	patient	NOUN
fnp-3528	90	4	,	,	PUNCT
fnp-3528	90	5	increased	increase	VERB
fnp-3528	90	6	abca7	abca7	NOUN
fnp-3528	90	7	transcription	transcription	NOUN
fnp-3528	90	8	has	have	AUX
fnp-3528	90	9	been	be	AUX
fnp-3528	90	10	found	find	VERB
fnp-3528	90	11	in	in	ADP
fnp-3528	90	12	areas	area	NOUN
fnp-3528	90	13	with	with	ADP
fnp-3528	90	14	plaques	plaque	NOUN
fnp-3528	90	15	but	but	CCONJ
fnp-3528	90	16	not	not	PART
fnp-3528	90	17	in	in	ADP
fnp-3528	90	18	unaltered	unaltered	ADJ
fnp-3528	90	19	regions	region	NOUN
fnp-3528	90	20	such	such	ADJ
fnp-3528	90	21	as	as	ADP
fnp-3528	90	22	the	the	DET
fnp-3528	90	23	cerebellum.123	cerebellum.123	NOUN
fnp-3528	90	24	this	this	DET
fnp-3528	90	25	increase	increase	NOUN
fnp-3528	90	26	in	in	ADP
fnp-3528	90	27	transcription	transcription	NOUN
fnp-3528	90	28	was	be	AUX
fnp-3528	90	29	paralleled	parallel	VERB
fnp-3528	90	30	by	by	ADP
fnp-3528	90	31	microglia	microglia	ADJ
fnp-3528	90	32	recruitment	recruitment	NOUN
fnp-3528	90	33	supporting	support	VERB
fnp-3528	90	34	the	the	DET
fnp-3528	90	35	contribution	contribution	NOUN
fnp-3528	90	36	of	of	ADP
fnp-3528	90	37	abca7	abca7	NOUN
fnp-3528	90	38	to	to	ADP
fnp-3528	90	39	microglia	microglia	ADJ
fnp-3528	90	40	-	-	PUNCT
fnp-3528	90	41	mediated	mediate	VERB
fnp-3528	90	42	phagocytosis	phagocytosis	NOUN
fnp-3528	90	43	of	of	ADP
fnp-3528	90	44	aβ	aβ	NOUN
fnp-3528	90	45	.	.	PUNCT
fnp-3528	91	1	in	in	ADP
fnp-3528	91	2	addition	addition	NOUN
fnp-3528	91	3	,	,	PUNCT
fnp-3528	91	4	abca7	abca7	PROPN
fnp-3528	91	5	knock	knock	VERB
fnp-3528	91	6	-	-	PUNCT
fnp-3528	91	7	out	out	ADP
fnp-3528	91	8	mice	mouse	NOUN
fnp-3528	91	9	showed	show	VERB
fnp-3528	91	10	a	a	DET
fnp-3528	91	11	reduced	reduced	ADJ
fnp-3528	91	12	microglia	microglia	ADJ
fnp-3528	91	13	response	response	NOUN
fnp-3528	91	14	after	after	ADP
fnp-3528	91	15	intracerebral	intracerebral	ADJ
fnp-3528	91	16	aβ	aβ	VERB
fnp-3528	91	17	injection.123	injection.123	PROPN
fnp-3528	91	18	kim	kim	PROPN
fnp-3528	91	19	et	et	PROPN
fnp-3528	91	20	al	al	PROPN
fnp-3528	91	21	.	.	PROPN
fnp-3528	91	22	demonstrated	demonstrate	VERB
fnp-3528	91	23	an	an	DET
fnp-3528	91	24	increased	increase	VERB
fnp-3528	91	25	aβ	aβ	NOUN
fnp-3528	91	26	load	load	NOUN
fnp-3528	91	27	in	in	ADP
fnp-3528	91	28	j20	j20	PROPN
fnp-3528	91	29	/	/	SYM
fnp-3528	91	30	a7	a7	PROPN
fnp-3528	91	31	knock	knock	NOUN
fnp-3528	91	32	-	-	PUNCT
fnp-3528	91	33	out	out	ADP
fnp-3528	91	34	mice	mouse	NOUN
fnp-3528	91	35	compared	compare	VERB
fnp-3528	91	36	to	to	ADP
fnp-3528	91	37	j20	j20	PROPN
fnp-3528	91	38	mice	mouse	NOUN
fnp-3528	91	39	,	,	PUNCT
fnp-3528	91	40	potentially	potentially	ADV
fnp-3528	91	41	due	due	ADJ
fnp-3528	91	42	to	to	ADP
fnp-3528	91	43	an	an	DET
fnp-3528	91	44	altered	altered	ADJ
fnp-3528	91	45	phagocytic	phagocytic	ADJ
fnp-3528	91	46	function.124,198	function.124,198	NOUN
fnp-3528	91	47	furthermore	furthermore	ADV
fnp-3528	91	48	,	,	PUNCT
fnp-3528	91	49	it	it	PRON
fnp-3528	91	50	has	have	AUX
fnp-3528	91	51	recently	recently	ADV
fnp-3528	91	52	been	be	AUX
fnp-3528	91	53	shown	show	VERB
fnp-3528	91	54	that	that	SCONJ
fnp-3528	91	55	abca7	abca7	PROPN
fnp-3528	91	56	haplodeficiency	haplodeficiency	NOUN
fnp-3528	91	57	disturbs	disturb	VERB
fnp-3528	91	58	the	the	DET
fnp-3528	91	59	microglial	microglial	ADJ
fnp-3528	91	60	immune	immune	ADJ
fnp-3528	91	61	response	response	NOUN
fnp-3528	91	62	and	and	CCONJ
fnp-3528	91	63	causes	cause	NOUN
fnp-3528	91	64	enhanced	enhance	VERB
fnp-3528	91	65	aβ	aβ	PRON
fnp-3528	91	66	accumulation	accumulation	NOUN
fnp-3528	91	67	in	in	ADP
fnp-3528	91	68	microglia	microglia	NOUN
fnp-3528	91	69	,	,	PUNCT
fnp-3528	91	70	probably	probably	ADV
fnp-3528	91	71	due	due	ADP
fnp-3528	91	72	to	to	ADP
fnp-3528	91	73	alterations	alteration	NOUN
fnp-3528	91	74	in	in	ADP
fnp-3528	91	75	endolysosomal	endolysosomal	ADJ
fnp-3528	91	76	trafficking.219	trafficking.219	ADJ
fnp-3528	91	77	last	last	ADV
fnp-3528	91	78	,	,	PUNCT
fnp-3528	91	79	a	a	DET
fnp-3528	91	80	new	new	ADJ
fnp-3528	91	81	hypothesis	hypothesis	NOUN
fnp-3528	91	82	has	have	AUX
fnp-3528	91	83	emerged	emerge	VERB
fnp-3528	91	84	recently	recently	ADV
fnp-3528	91	85	,	,	PUNCT
fnp-3528	91	86	assigning	assign	VERB
fnp-3528	91	87	abca7	abca7	PROPN
fnp-3528	91	88	a	a	DET
fnp-3528	91	89	prominent	prominent	ADJ
fnp-3528	91	90	role	role	NOUN
fnp-3528	91	91	in	in	ADP
fnp-3528	91	92	the	the	DET
fnp-3528	91	93	altered	alter	VERB
fnp-3528	91	94	lipidostasis	lipidostasis	NOUN
fnp-3528	91	95	hypothesis	hypothesis	NOUN
fnp-3528	91	96	in	in	ADP
fnp-3528	91	97	ad.104	ad.104	PROPN
fnp-3528	91	98	the	the	DET
fnp-3528	91	99	authors	author	NOUN
fnp-3528	91	100	of	of	ADP
fnp-3528	91	101	this	this	DET
fnp-3528	91	102	study	study	NOUN
fnp-3528	91	103	proposed	propose	VERB
fnp-3528	91	104	the	the	DET
fnp-3528	91	105	existence	existence	NOUN
fnp-3528	91	106	of	of	ADP
fnp-3528	91	107	a	a	DET
fnp-3528	91	108	neurodegenerative	neurodegenerative	ADJ
fnp-3528	91	109	lipid	lipid	NOUN
fnp-3528	91	110	that	that	PRON
fnp-3528	91	111	is	be	AUX
fnp-3528	91	112	naturally	naturally	ADV
fnp-3528	91	113	removed	remove	VERB
fnp-3528	91	114	by	by	ADP
fnp-3528	91	115	abca7	abca7	PROPN
fnp-3528	91	116	.	.	PUNCT
fnp-3528	92	1	a	a	DET
fnp-3528	92	2	loss	loss	NOUN
fnp-3528	92	3	of	of	ADP
fnp-3528	92	4	abca7	abca7	PROPN
fnp-3528	92	5	function	function	NOUN
fnp-3528	92	6	due	due	ADP
fnp-3528	92	7	to	to	ADP
fnp-3528	92	8	the	the	DET
fnp-3528	92	9	described	describe	VERB
fnp-3528	92	10	polymorphisms	polymorphism	NOUN
fnp-3528	92	11	might	might	AUX
fnp-3528	92	12	accelerate	accelerate	VERB
fnp-3528	92	13	accumulation	accumulation	NOUN
fnp-3528	92	14	of	of	ADP
fnp-3528	92	15	this	this	DET
fnp-3528	92	16	lipid	lipid	NOUN
fnp-3528	92	17	,	,	PUNCT
fnp-3528	92	18	inducing	induce	VERB
fnp-3528	92	19	aβ	aβ	ADP
fnp-3528	92	20	aggregation	aggregation	NOUN
fnp-3528	92	21	.	.	PUNCT
fnp-3528	93	1	in	in	ADP
fnp-3528	93	2	fact	fact	NOUN
fnp-3528	93	3	,	,	PUNCT
fnp-3528	93	4	a	a	DET
fnp-3528	93	5	link	link	NOUN
fnp-3528	93	6	between	between	ADP
fnp-3528	93	7	cholesterol	cholesterol	NOUN
fnp-3528	93	8	metabolism	metabolism	NOUN
fnp-3528	93	9	and	and	CCONJ
fnp-3528	93	10	abca7	abca7	NOUN
fnp-3528	93	11	-	-	PUNCT
fnp-3528	93	12	mediated	mediate	VERB
fnp-3528	93	13	phagocytosis	phagocytosis	NOUN
fnp-3528	93	14	has	have	AUX
fnp-3528	93	15	been	be	AUX
fnp-3528	93	16	reported	report	VERB
fnp-3528	93	17	,	,	PUNCT
fnp-3528	93	18	which	which	PRON
fnp-3528	93	19	may	may	AUX
fnp-3528	93	20	also	also	ADV
fnp-3528	93	21	explain	explain	VERB
fnp-3528	93	22	the	the	DET
fnp-3528	93	23	protective	protective	ADJ
fnp-3528	93	24	properties	property	NOUN
fnp-3528	93	25	of	of	ADP
fnp-3528	93	26	statin	statin	ADJ
fnp-3528	93	27	treatment	treatment	NOUN
fnp-3528	93	28	in	in	ADP
fnp-3528	93	29	the	the	DET
fnp-3528	93	30	development	development	NOUN
fnp-3528	93	31	of	of	ADP
fnp-3528	93	32	ad.105,198,203,220	ad.105,198,203,220	NOUN
fnp-3528	93	33	despite	despite	SCONJ
fnp-3528	93	34	recent	recent	ADJ
fnp-3528	93	35	findings	finding	NOUN
fnp-3528	93	36	,	,	PUNCT
fnp-3528	93	37	the	the	DET
fnp-3528	93	38	role	role	NOUN
fnp-3528	93	39	of	of	ADP
fnp-3528	93	40	abca7	abca7	NOUN
fnp-3528	93	41	in	in	ADP
fnp-3528	93	42	ad	ad	NOUN
fnp-3528	93	43	pathogenesis	pathogenesis	NOUN
fnp-3528	93	44	remains	remain	VERB
fnp-3528	93	45	unclear	unclear	ADJ
fnp-3528	93	46	.	.	PUNCT
fnp-3528	94	1	according	accord	VERB
fnp-3528	94	2	to	to	ADP
fnp-3528	94	3	in	in	ADP
fnp-3528	94	4	vitro	vitro	X
fnp-3528	94	5	and	and	CCONJ
fnp-3528	94	6	preclinical	preclinical	ADJ
fnp-3528	94	7	research	research	NOUN
fnp-3528	94	8	,	,	PUNCT
fnp-3528	94	9	it	it	PRON
fnp-3528	94	10	may	may	AUX
fnp-3528	94	11	be	be	AUX
fnp-3528	94	12	associated	associate	VERB
fnp-3528	94	13	with	with	ADP
fnp-3528	94	14	phagocytic	phagocytic	ADJ
fnp-3528	94	15	activity	activity	NOUN
fnp-3528	94	16	by	by	ADP
fnp-3528	94	17	microglia	microglia	NOUN
fnp-3528	94	18	,	,	PUNCT
fnp-3528	94	19	which	which	PRON
fnp-3528	94	20	could	could	AUX
fnp-3528	94	21	be	be	AUX
fnp-3528	94	22	linked	link	VERB
fnp-3528	94	23	to	to	ADP
fnp-3528	94	24	cell	cell	VERB
fnp-3528	94	25	cholesterol	cholesterol	NOUN
fnp-3528	94	26	metabolism.105,198,203	metabolism.105,198,203	PROPN
fnp-3528	94	27	thus	thus	ADV
fnp-3528	94	28	,	,	PUNCT
fnp-3528	94	29	further	further	ADJ
fnp-3528	94	30	investigation	investigation	NOUN
fnp-3528	94	31	is	be	AUX
fnp-3528	94	32	required	require	VERB
fnp-3528	94	33	to	to	PART
fnp-3528	94	34	reveal	reveal	VERB
fnp-3528	94	35	the	the	DET
fnp-3528	94	36	role	role	NOUN
fnp-3528	94	37	of	of	ADP
fnp-3528	94	38	abca7	abca7	NOUN
fnp-3528	94	39	in	in	ADP
fnp-3528	94	40	ad	ad	NOUN
fnp-3528	94	41	pathogenesis	pathogenesis	NOUN
fnp-3528	94	42	and	and	CCONJ
fnp-3528	94	43	its	its	PRON
fnp-3528	94	44	potential	potential	ADJ
fnp-3528	94	45	use	use	NOUN
fnp-3528	94	46	as	as	ADP
fnp-3528	94	47	a	a	DET
fnp-3528	94	48	therapeutic	therapeutic	ADJ
fnp-3528	94	49	target	target	NOUN
fnp-3528	94	50	for	for	ADP
fnp-3528	94	51	this	this	DET
fnp-3528	94	52	neurodegenerative	neurodegenerative	ADJ
fnp-3528	94	53	disease	disease	NOUN
fnp-3528	94	54	.	.	PUNCT
fnp-3528	95	1	abca8	abca8	PROPN
fnp-3528	95	2	–	–	PUNCT
fnp-3528	95	3	abca10	abca10	VERB
fnp-3528	95	4	so	so	ADV
fnp-3528	95	5	far	far	ADV
fnp-3528	95	6	,	,	PUNCT
fnp-3528	95	7	no	no	DET
fnp-3528	95	8	obvious	obvious	ADJ
fnp-3528	95	9	role	role	NOUN
fnp-3528	95	10	of	of	ADP
fnp-3528	95	11	abca8–10	abca8–10	NOUN
fnp-3528	95	12	has	have	AUX
fnp-3528	95	13	been	be	AUX
fnp-3528	95	14	elucidated	elucidate	VERB
fnp-3528	95	15	for	for	ADP
fnp-3528	95	16	ad	ad	NOUN
fnp-3528	95	17	,	,	PUNCT
fnp-3528	95	18	neurodegenerative	neurodegenerative	ADJ
fnp-3528	95	19	diseases	disease	NOUN
fnp-3528	95	20	,	,	PUNCT
fnp-3528	95	21	nor	nor	CCONJ
fnp-3528	95	22	any	any	DET
fnp-3528	95	23	human	human	ADJ
fnp-3528	95	24	disease	disease	NOUN
fnp-3528	95	25	.	.	PUNCT
fnp-3528	96	1	however	however	ADV
fnp-3528	96	2	,	,	PUNCT
fnp-3528	96	3	several	several	ADJ
fnp-3528	96	4	potential	potential	ADJ
fnp-3528	96	5	intrinsic	intrinsic	ADJ
fnp-3528	96	6	substrates	substrate	NOUN
fnp-3528	96	7	of	of	ADP
fnp-3528	96	8	abca8	abca8	PROPN
fnp-3528	96	9	have	have	AUX
fnp-3528	96	10	been	be	AUX
fnp-3528	96	11	identified.10,221,222	identified.10,221,222	NOUN
fnp-3528	96	12	furthermore	furthermore	ADV
fnp-3528	96	13	,	,	PUNCT
fnp-3528	96	14	a	a	DET
fnp-3528	96	15	significant	significant	ADJ
fnp-3528	96	16	number	number	NOUN
fnp-3528	96	17	of	of	ADP
fnp-3528	96	18	abca	abca	NOUN
fnp-3528	96	19	transporter	transporter	NOUN
fnp-3528	96	20	modulators	modulator	NOUN
fnp-3528	96	21	have	have	AUX
fnp-3528	96	22	been	be	AUX
fnp-3528	96	23	identified	identify	VERB
fnp-3528	96	24	on	on	ADP
fnp-3528	96	25	this	this	DET
fnp-3528	96	26	target.222	target.222	NOUN
fnp-3528	96	27	hence	hence	ADV
fnp-3528	96	28	,	,	PUNCT
fnp-3528	96	29	abca8	abca8	PROPN
fnp-3528	96	30	represents	represent	VERB
fnp-3528	96	31	a	a	DET
fnp-3528	96	32	good	good	ADJ
fnp-3528	96	33	model	model	NOUN
fnp-3528	96	34	system	system	NOUN
fnp-3528	96	35	for	for	ADP
fnp-3528	96	36	the	the	DET
fnp-3528	96	37	development	development	NOUN
fnp-3528	96	38	of	of	ADP
fnp-3528	96	39	potential	potential	ADJ
fnp-3528	96	40	therapeutics	therapeutic	NOUN
fnp-3528	96	41	targeting	target	VERB
fnp-3528	96	42	other	other	ADJ
fnp-3528	96	43	abca	abca	NOUN
fnp-3528	96	44	transporters	transporter	NOUN
fnp-3528	96	45	taking	take	VERB
fnp-3528	96	46	the	the	DET
fnp-3528	96	47	scarce	scarce	ADJ
fnp-3528	96	48	knowledge	knowledge	NOUN
fnp-3528	96	49	on	on	ADP
fnp-3528	96	50	this	this	DET
fnp-3528	96	51	transporter	transporter	NOUN
fnp-3528	96	52	subclass	subclass	NOUN
fnp-3528	96	53	into	into	ADP
fnp-3528	96	54	account	account	NOUN
fnp-3528	96	55	.	.	PUNCT
fnp-3528	97	1	abca12	abca12	PROPN
fnp-3528	97	2	abca12	abca12	NOUN
fnp-3528	97	3	is	be	AUX
fnp-3528	97	4	expressed	express	VERB
fnp-3528	97	5	predominantly	predominantly	ADV
fnp-3528	97	6	in	in	ADP
fnp-3528	97	7	the	the	DET
fnp-3528	97	8	epidermis	epidermis	NOUN
fnp-3528	97	9	,	,	PUNCT
fnp-3528	97	10	and	and	CCONJ
fnp-3528	97	11	its	its	PRON
fnp-3528	97	12	main	main	ADJ
fnp-3528	97	13	function	function	NOUN
fnp-3528	97	14	is	be	AUX
fnp-3528	97	15	the	the	DET
fnp-3528	97	16	transport	transport	NOUN
fnp-3528	97	17	of	of	ADP
fnp-3528	97	18	lipids.223	lipids.223	NOUN
fnp-3528	97	19	it	it	PRON
fnp-3528	97	20	is	be	AUX
fnp-3528	97	21	hypothesized	hypothesize	VERB
fnp-3528	97	22	that	that	SCONJ
fnp-3528	97	23	abca12	abca12	NOUN
fnp-3528	97	24	plays	play	VERB
fnp-3528	97	25	a	a	DET
fnp-3528	97	26	role	role	NOUN
fnp-3528	97	27	in	in	ADP
fnp-3528	97	28	skin	skin	NOUN
fnp-3528	97	29	lipid	lipid	NOUN
fnp-3528	97	30	homeostasis	homeostasis	NOUN
fnp-3528	97	31	.	.	PUNCT
fnp-3528	98	1	mutations	mutation	NOUN
fnp-3528	98	2	in	in	ADP
fnp-3528	98	3	this	this	DET
fnp-3528	98	4	gene	gene	NOUN
fnp-3528	98	5	are	be	AUX
fnp-3528	98	6	associated	associate	VERB
fnp-3528	98	7	with	with	ADP
fnp-3528	98	8	lamellar	lamellar	ADJ
fnp-3528	98	9	ichthyosis	ichthyosis	NOUN
fnp-3528	98	10	type	type	NOUN
fnp-3528	98	11	2	2	NUM
fnp-3528	98	12	and	and	CCONJ
fnp-3528	98	13	harlequin	harlequin	PROPN
fnp-3528	98	14	ichthyosis.143,224,225	ichthyosis.143,224,225	PROPN
fnp-3528	98	15	however	however	ADV
fnp-3528	98	16	,	,	PUNCT
fnp-3528	98	17	a	a	DET
fnp-3528	98	18	japanese	japanese	ADJ
fnp-3528	98	19	study	study	NOUN
fnp-3528	98	20	investigated	investigate	VERB
fnp-3528	98	21	common	common	ADJ
fnp-3528	98	22	polymorphisms	polymorphism	NOUN
fnp-3528	98	23	of	of	ADP
fnp-3528	98	24	abca12	abca12	NOUN
fnp-3528	98	25	and	and	CCONJ
fnp-3528	98	26	did	do	AUX
fnp-3528	98	27	not	not	PART
fnp-3528	98	28	find	find	VERB
fnp-3528	98	29	an	an	DET
fnp-3528	98	30	association	association	NOUN
fnp-3528	98	31	with	with	ADP
fnp-3528	98	32	sporadic	sporadic	ADJ
fnp-3528	98	33	ad.226	ad.226	PROPN
fnp-3528	98	34	abca13	abca13	NOUN
fnp-3528	98	35	abca13	abca13	NOUN
fnp-3528	98	36	is	be	AUX
fnp-3528	98	37	the	the	DET
fnp-3528	98	38	largest	large	ADJ
fnp-3528	98	39	abc	abc	NOUN
fnp-3528	98	40	transporter	transporter	NOUN
fnp-3528	98	41	with	with	ADP
fnp-3528	98	42	576	576	NUM
fnp-3528	98	43	kda.227	kda.227	NOUN
fnp-3528	98	44	it	it	PRON
fnp-3528	98	45	has	have	AUX
fnp-3528	98	46	been	be	AUX
fnp-3528	98	47	reported	report	VERB
fnp-3528	98	48	to	to	PART
fnp-3528	98	49	be	be	AUX
fnp-3528	98	50	highly	highly	ADV
fnp-3528	98	51	expressed	express	VERB
fnp-3528	98	52	in	in	ADP
fnp-3528	98	53	the	the	DET
fnp-3528	98	54	brain	brain	NOUN
fnp-3528	98	55	as	as	ADV
fnp-3528	98	56	well	well	ADV
fnp-3528	98	57	as	as	ADP
fnp-3528	98	58	in	in	ADP
fnp-3528	98	59	peripheral	peripheral	ADJ
fnp-3528	98	60	tissues.227	tissues.227	NOUN
fnp-3528	98	61	a	a	DET
fnp-3528	98	62	very	very	ADV
fnp-3528	98	63	small	small	ADJ
fnp-3528	98	64	study	study	NOUN
fnp-3528	98	65	found	find	VERB
fnp-3528	98	66	reduced	reduce	VERB
fnp-3528	98	67	neuroinflammation	neuroinflammation	NOUN
fnp-3528	98	68	and	and	CCONJ
fnp-3528	98	69	altered	altered	ADJ
fnp-3528	98	70	abca13	abca13	NOUN
fnp-3528	98	71	expression	expression	NOUN
fnp-3528	98	72	in	in	ADP
fnp-3528	98	73	post	post	NOUN
fnp-3528	98	74	mortem	mortem	X
fnp-3528	98	75	analyses	analysis	NOUN
fnp-3528	98	76	of	of	ADP
fnp-3528	98	77	brains	brain	NOUN
fnp-3528	98	78	from	from	ADP
fnp-3528	98	79	patients	patient	NOUN
fnp-3528	98	80	with	with	ADP
fnp-3528	98	81	lewy	lewy	ADJ
fnp-3528	98	82	body	body	NOUN
fnp-3528	98	83	dementia.64	dementia.64	NOUN
fnp-3528	98	84	in	in	ADP
fnp-3528	98	85	addition	addition	NOUN
fnp-3528	98	86	,	,	PUNCT
fnp-3528	98	87	increased	increase	VERB
fnp-3528	98	88	abca13	abca13	NOUN
fnp-3528	98	89	expression	expression	NOUN
fnp-3528	98	90	has	have	AUX
fnp-3528	98	91	been	be	AUX
fnp-3528	98	92	reported	report	VERB
fnp-3528	98	93	after	after	ADP
fnp-3528	98	94	stroke	stroke	NOUN
fnp-3528	98	95	in	in	ADP
fnp-3528	98	96	mice.67	mice.67	NOUN
fnp-3528	98	97	furthermore	furthermore	ADV
fnp-3528	98	98	,	,	PUNCT
fnp-3528	98	99	two	two	NUM
fnp-3528	98	100	studies	study	NOUN
fnp-3528	98	101	showed	show	VERB
fnp-3528	98	102	enhanced	enhanced	ADJ
fnp-3528	98	103	abca13	abca13	NOUN
fnp-3528	98	104	mrna	mrna	PROPN
fnp-3528	98	105	expression	expression	NOUN
fnp-3528	98	106	in	in	ADP
fnp-3528	98	107	schizophrenic	schizophrenic	ADJ
fnp-3528	98	108	patients	patient	NOUN
fnp-3528	98	109	after	after	ADP
fnp-3528	98	110	different	different	ADJ
fnp-3528	98	111	antipsychotic	antipsychotic	ADJ
fnp-3528	98	112	treatments	treatment	NOUN
fnp-3528	98	113	,	,	PUNCT
fnp-3528	98	114	suggesting	suggest	VERB
fnp-3528	98	115	a	a	DET
fnp-3528	98	116	role	role	NOUN
fnp-3528	98	117	of	of	ADP
fnp-3528	98	118	this	this	DET
fnp-3528	98	119	transporter	transporter	NOUN
fnp-3528	98	120	in	in	ADP
fnp-3528	98	121	psychiatric	psychiatric	ADJ
fnp-3528	98	122	disorders.48,65,66	disorders.48,65,66	VERB
fnp-3528	98	123	however	however	ADV
fnp-3528	98	124	,	,	PUNCT
fnp-3528	98	125	no	no	DET
fnp-3528	98	126	association	association	NOUN
fnp-3528	98	127	between	between	ADP
fnp-3528	98	128	abca13	abca13	NOUN
fnp-3528	98	129	and	and	CCONJ
fnp-3528	98	130	ad	ad	NOUN
fnp-3528	98	131	has	have	AUX
fnp-3528	98	132	been	be	AUX
fnp-3528	98	133	found	find	VERB
fnp-3528	98	134	.	.	PUNCT
fnp-3528	99	1	figure	figure	VERB
fnp-3528	99	2	1	1	NUM
fnp-3528	99	3	.	.	PUNCT
fnp-3528	100	1	molecular	molecular	ADJ
fnp-3528	100	2	formulas	formula	NOUN
fnp-3528	100	3	of	of	ADP
fnp-3528	100	4	prominent	prominent	ADJ
fnp-3528	100	5	interactors	interactor	NOUN
fnp-3528	100	6	of	of	ADP
fnp-3528	100	7	abca	abca	PROPN
fnp-3528	100	8	transporters	transporter	NOUN
fnp-3528	100	9	.	.	PUNCT
fnp-3528	101	1	modulators	modulator	NOUN
fnp-3528	101	2	of	of	ADP
fnp-3528	101	3	abca	abca	NOUN
fnp-3528	101	4	transporter	transporter	NOUN
fnp-3528	101	5	function	function	NOUN
fnp-3528	101	6	,	,	PUNCT
fnp-3528	101	7	trafficking	trafficking	NOUN
fnp-3528	101	8	,	,	PUNCT
fnp-3528	101	9	and	and	CCONJ
fnp-3528	101	10	regulation	regulation	NOUN
fnp-3528	101	11	‘	'	PUNCT
fnp-3528	101	12	modulation	modulation	NOUN
fnp-3528	101	13	’	'	PUNCT
fnp-3528	101	14	is	be	AUX
fnp-3528	101	15	a	a	DET
fnp-3528	101	16	widely	widely	ADV
fnp-3528	101	17	used	use	VERB
fnp-3528	101	18	term	term	NOUN
fnp-3528	101	19	to	to	PART
fnp-3528	101	20	summarize	summarize	VERB
fnp-3528	101	21	actions	action	NOUN
fnp-3528	101	22	of	of	ADP
fnp-3528	101	23	small	small	ADJ
fnp-3528	101	24	-	-	PUNCT
fnp-3528	101	25	molecules	molecule	NOUN
fnp-3528	101	26	that	that	PRON
fnp-3528	101	27	have	have	AUX
fnp-3528	101	28	been	be	AUX
fnp-3528	101	29	reported	report	VERB
fnp-3528	101	30	to	to	PART
fnp-3528	101	31	alter	alter	VERB
fnp-3528	101	32	abca	abca	NOUN
fnp-3528	101	33	transporter	transporter	NOUN
fnp-3528	101	34	function	function	NOUN
fnp-3528	101	35	,	,	PUNCT
fnp-3528	101	36	trafficking	trafficking	NOUN
fnp-3528	101	37	,	,	PUNCT
fnp-3528	101	38	and/or	and/or	CCONJ
fnp-3528	101	39	regulation	regulation	NOUN
fnp-3528	101	40	.	.	PUNCT
fnp-3528	102	1	modulators	modulator	NOUN
fnp-3528	102	2	can	can	AUX
fnp-3528	102	3	be	be	AUX
fnp-3528	102	4	divided	divide	VERB
fnp-3528	102	5	into	into	ADP
fnp-3528	102	6	‘	'	PUNCT
fnp-3528	102	7	interactors	interactor	NOUN
fnp-3528	102	8	’	'	PUNCT
fnp-3528	102	9	and	and	CCONJ
fnp-3528	102	10	‘	'	PUNCT
fnp-3528	102	11	regulators	regulator	NOUN
fnp-3528	102	12	’	'	PUNCT
fnp-3528	102	13	.	.	PUNCT
fnp-3528	103	1	interactors	interactor	NOUN
fnp-3528	103	2	summarize	summarize	VERB
fnp-3528	103	3	compounds	compound	NOUN
fnp-3528	103	4	that	that	PRON
fnp-3528	103	5	directly	directly	ADV
fnp-3528	103	6	bind	bind	VERB
fnp-3528	103	7	to	to	ADP
fnp-3528	103	8	abca	abca	NOUN
fnp-3528	103	9	transports	transport	NOUN
fnp-3528	103	10	,	,	PUNCT
fnp-3528	103	11	which	which	PRON
fnp-3528	103	12	can	can	AUX
fnp-3528	103	13	have	have	AUX
fnp-3528	103	14	either	either	CCONJ
fnp-3528	103	15	inhibiting	inhibit	VERB
fnp-3528	103	16	or	or	CCONJ
fnp-3528	103	17	activating	activate	VERB
fnp-3528	103	18	effects	effect	NOUN
fnp-3528	103	19	on	on	ADP
fnp-3528	103	20	the	the	DET
fnp-3528	103	21	transporters	transporter	NOUN
fnp-3528	103	22	.	.	PUNCT
fnp-3528	104	1	substrates	substrate	NOUN
fnp-3528	104	2	are	be	AUX
fnp-3528	104	3	also	also	ADV
fnp-3528	104	4	included	include	VERB
fnp-3528	104	5	in	in	ADP
fnp-3528	104	6	this	this	DET
fnp-3528	104	7	category	category	NOUN
fnp-3528	104	8	.	.	PUNCT
fnp-3528	105	1	in	in	ADP
fnp-3528	105	2	terms	term	NOUN
fnp-3528	105	3	of	of	ADP
fnp-3528	105	4	abca	abca	NOUN
fnp-3528	105	5	transporters	transporter	NOUN
fnp-3528	105	6	,	,	PUNCT
fnp-3528	105	7	however	however	ADV
fnp-3528	105	8	,	,	PUNCT
fnp-3528	105	9	a	a	DET
fnp-3528	105	10	direct	direct	ADJ
fnp-3528	105	11	interaction	interaction	NOUN
fnp-3528	105	12	of	of	ADP
fnp-3528	105	13	these	these	DET
fnp-3528	105	14	agents	agent	NOUN
fnp-3528	105	15	with	with	ADP
fnp-3528	105	16	their	their	PRON
fnp-3528	105	17	target(s	target(s	NOUN
fnp-3528	105	18	)	)	PUNCT
fnp-3528	105	19	has	have	AUX
fnp-3528	105	20	in	in	ADP
fnp-3528	105	21	most	most	ADJ
fnp-3528	105	22	cases	case	NOUN
fnp-3528	105	23	not	not	PART
fnp-3528	105	24	yet	yet	ADV
fnp-3528	105	25	been	be	AUX
fnp-3528	105	26	comprehensively	comprehensively	ADV
fnp-3528	105	27	proven	prove	VERB
fnp-3528	105	28	.	.	PUNCT
fnp-3528	106	1	therefore	therefore	ADV
fnp-3528	106	2	,	,	PUNCT
fnp-3528	106	3	compounds	compound	VERB
fnp-3528	106	4	that	that	PRON
fnp-3528	106	5	are	be	AUX
fnp-3528	106	6	believed	believe	VERB
fnp-3528	106	7	to	to	PART
fnp-3528	106	8	directly	directly	ADV
fnp-3528	106	9	interact	interact	VERB
fnp-3528	106	10	with	with	ADP
fnp-3528	106	11	abca	abca	PROPN
fnp-3528	106	12	transporters	transporter	NOUN
fnp-3528	106	13	extend	extend	VERB
fnp-3528	106	14	the	the	DET
fnp-3528	106	15	category	category	NOUN
fnp-3528	106	16	of	of	ADP
fnp-3528	106	17	interactors	interactor	NOUN
fnp-3528	106	18	.	.	PUNCT
fnp-3528	107	1	figure	figure	VERB
fnp-3528	107	2	 	 	SPACE
fnp-3528	107	3	1	1	NUM
fnp-3528	107	4	represents	represent	VERB
fnp-3528	107	5	the	the	DET
fnp-3528	107	6	most	most	ADV
fnp-3528	107	7	prominent	prominent	ADJ
fnp-3528	107	8	interactors	interactor	NOUN
fnp-3528	107	9	of	of	ADP
fnp-3528	107	10	abca	abca	NOUN
fnp-3528	107	11	transporters	transporter	NOUN
fnp-3528	107	12	and	and	CCONJ
fnp-3528	107	13	provides	provide	VERB
fnp-3528	107	14	additional	additional	ADJ
fnp-3528	107	15	information	information	NOUN
fnp-3528	107	16	about	about	ADP
fnp-3528	107	17	their	their	PRON
fnp-3528	107	18	mode	mode	NOUN
fnp-3528	107	19	of	of	ADP
fnp-3528	107	20	modulation	modulation	NOUN
fnp-3528	107	21	.	.	PUNCT
fnp-3528	108	1	regulators	regulator	NOUN
fnp-3528	108	2	are	be	AUX
fnp-3528	108	3	compounds	compound	NOUN
fnp-3528	108	4	that	that	PRON
fnp-3528	108	5	change	change	VERB
fnp-3528	108	6	abca	abca	NOUN
fnp-3528	108	7	transporter	transporter	NOUN
fnp-3528	108	8	expression	expression	NOUN
fnp-3528	108	9	(	(	PUNCT
fnp-3528	108	10	transcription	transcription	NOUN
fnp-3528	108	11	and/or	and/or	CCONJ
fnp-3528	108	12	translation	translation	NOUN
fnp-3528	108	13	)	)	PUNCT
fnp-3528	108	14	in	in	ADP
fnp-3528	108	15	terms	term	NOUN
fnp-3528	108	16	of	of	ADP
fnp-3528	108	17	induction	induction	NOUN
fnp-3528	108	18	and/or	and/or	CCONJ
fnp-3528	108	19	downregulation	downregulation	NOUN
fnp-3528	108	20	.	.	PUNCT
fnp-3528	109	1	in	in	ADP
fnp-3528	109	2	addition	addition	NOUN
fnp-3528	109	3	,	,	PUNCT
fnp-3528	109	4	compounds	compound	VERB
fnp-3528	109	5	that	that	PRON
fnp-3528	109	6	regulate	regulate	VERB
fnp-3528	109	7	abca	abca	NOUN
fnp-3528	109	8	transporter	transporter	NOUN
fnp-3528	109	9	trafficking	trafficking	NOUN
fnp-3528	109	10	can	can	AUX
fnp-3528	109	11	be	be	AUX
fnp-3528	109	12	included	include	VERB
fnp-3528	109	13	into	into	ADP
fnp-3528	109	14	the	the	DET
fnp-3528	109	15	category	category	NOUN
fnp-3528	109	16	of	of	ADP
fnp-3528	109	17	regulators	regulator	NOUN
fnp-3528	109	18	,	,	PUNCT
fnp-3528	109	19	as	as	SCONJ
fnp-3528	109	20	this	this	DET
fnp-3528	109	21	effect	effect	NOUN
fnp-3528	109	22	was	be	AUX
fnp-3528	109	23	often	often	ADV
fnp-3528	109	24	observed	observe	VERB
fnp-3528	109	25	as	as	ADP
fnp-3528	109	26	‘	'	PUNCT
fnp-3528	109	27	pseudo	pseudo	NOUN
fnp-3528	109	28	-	-	ADJ
fnp-3528	109	29	protein	protein	ADJ
fnp-3528	109	30	increase	increase	NOUN
fnp-3528	109	31	’	'	PUNCT
fnp-3528	109	32	at	at	ADP
fnp-3528	109	33	the	the	DET
fnp-3528	109	34	cell	cell	NOUN
fnp-3528	109	35	membrane	membrane	NOUN
fnp-3528	109	36	.	.	PUNCT
fnp-3528	110	1	figure	figure	NOUN
fnp-3528	110	2	 	 	SPACE
fnp-3528	110	3	2	2	NUM
fnp-3528	110	4	depicts	depict	VERB
fnp-3528	110	5	the	the	DET
fnp-3528	110	6	most	most	ADV
fnp-3528	110	7	prominent	prominent	ADJ
fnp-3528	110	8	regulators	regulator	NOUN
fnp-3528	110	9	of	of	ADP
fnp-3528	110	10	abca	abca	NOUN
fnp-3528	110	11	transporters	transporter	NOUN
fnp-3528	110	12	including	include	VERB
fnp-3528	110	13	proposed	propose	VERB
fnp-3528	110	14	mode	mode	NOUN
fnp-3528	110	15	of	of	ADP
fnp-3528	110	16	modulations	modulation	NOUN
fnp-3528	110	17	.	.	PUNCT
fnp-3528	111	1	figure	figure	NOUN
fnp-3528	111	2	2	2	NUM
fnp-3528	111	3	.	.	PUNCT
fnp-3528	112	1	molecular	molecular	ADJ
fnp-3528	112	2	formulas	formula	NOUN
fnp-3528	112	3	of	of	ADP
fnp-3528	112	4	prominent	prominent	ADJ
fnp-3528	112	5	regulators	regulator	NOUN
fnp-3528	112	6	of	of	ADP
fnp-3528	112	7	abca	abca	NOUN
fnp-3528	112	8	transporters	transporter	NOUN
fnp-3528	112	9	.	.	PUNCT
fnp-3528	113	1	it	it	PRON
fnp-3528	113	2	must	must	AUX
fnp-3528	113	3	be	be	AUX
fnp-3528	113	4	stated	state	VERB
fnp-3528	113	5	that	that	SCONJ
fnp-3528	113	6	the	the	DET
fnp-3528	113	7	term	term	NOUN
fnp-3528	113	8	‘	'	PUNCT
fnp-3528	113	9	inhibitor	inhibitor	NOUN
fnp-3528	113	10	’	'	PUNCT
fnp-3528	113	11	and	and	CCONJ
fnp-3528	113	12	‘	'	PUNCT
fnp-3528	113	13	activator	activator	NOUN
fnp-3528	113	14	’	'	PUNCT
fnp-3528	113	15	are	be	AUX
fnp-3528	113	16	often	often	ADV
fnp-3528	113	17	misused	misuse	VERB
fnp-3528	113	18	in	in	ADP
fnp-3528	113	19	the	the	DET
fnp-3528	113	20	literature	literature	NOUN
fnp-3528	113	21	,	,	PUNCT
fnp-3528	113	22	as	as	SCONJ
fnp-3528	113	23	in	in	ADP
fnp-3528	113	24	most	most	ADJ
fnp-3528	113	25	cases	case	NOUN
fnp-3528	113	26	studies	study	NOUN
fnp-3528	113	27	describe	describe	VERB
fnp-3528	113	28	a	a	DET
fnp-3528	113	29	downregulation	downregulation	NOUN
fnp-3528	113	30	or	or	CCONJ
fnp-3528	113	31	induction	induction	NOUN
fnp-3528	113	32	.	.	PUNCT
fnp-3528	114	1	in	in	ADP
fnp-3528	114	2	the	the	DET
fnp-3528	114	3	present	present	ADJ
fnp-3528	114	4	review	review	NOUN
fnp-3528	114	5	,	,	PUNCT
fnp-3528	114	6	this	this	DET
fnp-3528	114	7	mislabeling	mislabeling	NOUN
fnp-3528	114	8	has	have	AUX
fnp-3528	114	9	been	be	AUX
fnp-3528	114	10	taken	take	VERB
fnp-3528	114	11	into	into	ADP
fnp-3528	114	12	account	account	NOUN
fnp-3528	114	13	and	and	CCONJ
fnp-3528	114	14	the	the	DET
fnp-3528	114	15	present	present	ADJ
fnp-3528	114	16	review	review	NOUN
fnp-3528	114	17	and	and	CCONJ
fnp-3528	114	18	the	the	DET
fnp-3528	114	19	respective	respective	ADJ
fnp-3528	114	20	compounds	compound	NOUN
fnp-3528	114	21	have	have	AUX
fnp-3528	114	22	been	be	AUX
fnp-3528	114	23	allocated	allocate	VERB
fnp-3528	114	24	into	into	ADP
fnp-3528	114	25	the	the	DET
fnp-3528	114	26	correct	correct	ADJ
fnp-3528	114	27	groups	group	NOUN
fnp-3528	114	28	.	.	PUNCT
fnp-3528	115	1	as	as	SCONJ
fnp-3528	115	2	established	establish	VERB
fnp-3528	115	3	earlier,23,24	earlier,23,24	PRON
fnp-3528	115	4	the	the	DET
fnp-3528	115	5	compounds	compound	NOUN
fnp-3528	115	6	are	be	AUX
fnp-3528	115	7	sorted	sort	VERB
fnp-3528	115	8	according	accord	VERB
fnp-3528	115	9	to	to	ADP
fnp-3528	115	10	their	their	PRON
fnp-3528	115	11	origin	origin	NOUN
fnp-3528	115	12	:	:	PUNCT
fnp-3528	115	13	(	(	PUNCT
fnp-3528	115	14	i	i	NOUN
fnp-3528	115	15	)	)	PUNCT
fnp-3528	115	16	intrinsic	intrinsic	ADJ
fnp-3528	115	17	substrates	substrate	NOUN
fnp-3528	115	18	and	and	CCONJ
fnp-3528	115	19	substrate	substrate	NOUN
fnp-3528	115	20	-	-	PUNCT
fnp-3528	115	21	like	like	ADJ
fnp-3528	115	22	molecules	molecule	NOUN
fnp-3528	115	23	,	,	PUNCT
fnp-3528	115	24	(	(	PUNCT
fnp-3528	115	25	ii	ii	NOUN
fnp-3528	115	26	)	)	PUNCT
fnp-3528	115	27	(	(	PUNCT
fnp-3528	115	28	other	other	ADJ
fnp-3528	115	29	)	)	PUNCT
fnp-3528	115	30	natural	natural	ADJ
fnp-3528	115	31	compounds	compound	NOUN
fnp-3528	115	32	,	,	PUNCT
fnp-3528	115	33	(	(	PUNCT
fnp-3528	115	34	iii	iii	NOUN
fnp-3528	115	35	)	)	PUNCT
fnp-3528	115	36	pharmacological	pharmacological	ADJ
fnp-3528	115	37	drugs	drug	NOUN
fnp-3528	115	38	,	,	PUNCT
fnp-3528	115	39	(	(	PUNCT
fnp-3528	115	40	iv	iv	X
fnp-3528	115	41	)	)	PUNCT
fnp-3528	115	42	high	high	ADJ
fnp-3528	115	43	-	-	PUNCT
fnp-3528	115	44	throughput	throughput	NOUN
fnp-3528	115	45	screening-(hts)-derived	screening-(hts)-derive	VERB
fnp-3528	115	46	candidates	candidate	NOUN
fnp-3528	115	47	,	,	PUNCT
fnp-3528	115	48	as	as	ADV
fnp-3528	115	49	well	well	ADV
fnp-3528	115	50	as	as	ADP
fnp-3528	115	51	(	(	PUNCT
fnp-3528	115	52	v	v	NOUN
fnp-3528	115	53	)	)	PUNCT
fnp-3528	115	54	compounds	compound	NOUN
fnp-3528	115	55	from	from	ADP
fnp-3528	115	56	synthetic	synthetic	ADJ
fnp-3528	115	57	/	/	SYM
fnp-3528	115	58	medicinal	medicinal	ADJ
fnp-3528	115	59	chemistry	chemistry	NOUN
fnp-3528	115	60	approaches	approach	NOUN
fnp-3528	115	61	.	.	PUNCT
fnp-3528	116	1	figure	figure	NOUN
fnp-3528	116	2	 	 	SPACE
fnp-3528	116	3	3	3	NUM
fnp-3528	116	4	gives	give	VERB
fnp-3528	116	5	a	a	DET
fnp-3528	116	6	general	general	ADJ
fnp-3528	116	7	overview	overview	NOUN
fnp-3528	116	8	of	of	ADP
fnp-3528	116	9	specific	specific	ADJ
fnp-3528	116	10	interactors	interactor	NOUN
fnp-3528	116	11	and	and	CCONJ
fnp-3528	116	12	their	their	PRON
fnp-3528	116	13	postulated	postulate	VERB
fnp-3528	116	14	mode	mode	NOUN
fnp-3528	116	15	of	of	ADP
fnp-3528	116	16	modulation	modulation	NOUN
fnp-3528	116	17	.	.	PUNCT
fnp-3528	117	1	table	table	NOUN
fnp-3528	117	2	 	 	SPACE
fnp-3528	117	3	2	2	NUM
fnp-3528	117	4	summarizes	summarize	NOUN
fnp-3528	117	5	all	all	DET
fnp-3528	117	6	modulators	modulator	NOUN
fnp-3528	117	7	of	of	ADP
fnp-3528	117	8	abca1	abca1	NOUN
fnp-3528	117	9	,	,	PUNCT
fnp-3528	117	10	the	the	DET
fnp-3528	117	11	most	most	ADV
fnp-3528	117	12	studied	study	VERB
fnp-3528	117	13	abca	abca	NOUN
fnp-3528	117	14	transporter	transporter	NOUN
fnp-3528	117	15	,	,	PUNCT
fnp-3528	117	16	while	while	SCONJ
fnp-3528	117	17	table	table	NOUN
fnp-3528	117	18	 	 	SPACE
fnp-3528	117	19	3	3	NUM
fnp-3528	117	20	summarizes	summarize	NOUN
fnp-3528	117	21	all	all	DET
fnp-3528	117	22	known	know	VERB
fnp-3528	117	23	modulators	modulator	NOUN
fnp-3528	117	24	in	in	ADP
fnp-3528	117	25	terms	term	NOUN
fnp-3528	117	26	of	of	ADP
fnp-3528	117	27	the	the	DET
fnp-3528	117	28	other	other	ADJ
fnp-3528	117	29	abca	abca	PROPN
fnp-3528	117	30	transporters	transporter	NOUN
fnp-3528	117	31	.	.	PUNCT
fnp-3528	118	1	the	the	DET
fnp-3528	118	2	stated	state	VERB
fnp-3528	118	3	concentration	concentration	NOUN
fnp-3528	118	4	values	value	NOUN
fnp-3528	118	5	are	be	AUX
fnp-3528	118	6	indicators	indicator	NOUN
fnp-3528	118	7	of	of	ADP
fnp-3528	118	8	bioactivities	bioactivitie	NOUN
fnp-3528	118	9	of	of	ADP
fnp-3528	118	10	the	the	DET
fnp-3528	118	11	respective	respective	ADJ
fnp-3528	118	12	compound	compound	NOUN
fnp-3528	118	13	and	and	CCONJ
fnp-3528	118	14	are	be	AUX
fnp-3528	118	15	strongly	strongly	ADV
fnp-3528	118	16	dependent	dependent	ADJ
fnp-3528	118	17	on	on	ADP
fnp-3528	118	18	the	the	DET
fnp-3528	118	19	testing	testing	NOUN
fnp-3528	118	20	system	system	NOUN
fnp-3528	118	21	utilized	utilize	VERB
fnp-3528	118	22	.	.	PUNCT
fnp-3528	119	1	hence	hence	ADV
fnp-3528	119	2	,	,	PUNCT
fnp-3528	119	3	the	the	DET
fnp-3528	119	4	respective	respective	ADJ
fnp-3528	119	5	data	datum	NOUN
fnp-3528	119	6	must	must	AUX
fnp-3528	119	7	be	be	AUX
fnp-3528	119	8	interpreted	interpret	VERB
fnp-3528	119	9	with	with	ADP
fnp-3528	119	10	caution	caution	NOUN
fnp-3528	119	11	.	.	PUNCT
fnp-3528	120	1	figure	figure	VERB
fnp-3528	120	2	3	3	NUM
fnp-3528	120	3	.	.	PUNCT
fnp-3528	120	4	general	general	ADJ
fnp-3528	120	5	overview	overview	NOUN
fnp-3528	120	6	of	of	ADP
fnp-3528	120	7	proteins	protein	NOUN
fnp-3528	120	8	participating	participate	VERB
fnp-3528	120	9	in	in	ADP
fnp-3528	120	10	abca1	abca1	NOUN
fnp-3528	120	11	regulation	regulation	NOUN
fnp-3528	120	12	and	and	CCONJ
fnp-3528	120	13	interaction	interaction	NOUN
fnp-3528	120	14	.	.	PUNCT
fnp-3528	121	1	small	small	ADJ
fnp-3528	121	2	-	-	PUNCT
fnp-3528	121	3	molecule	molecule	NOUN
fnp-3528	121	4	interactors	interactor	NOUN
fnp-3528	121	5	of	of	ADP
fnp-3528	121	6	abca	abca	PROPN
fnp-3528	121	7	transporters	transporter	NOUN
fnp-3528	121	8	endoand	endoand	PROPN
fnp-3528	121	9	xenobiotic	xenobiotic	ADJ
fnp-3528	121	10	substrates	substrate	VERB
fnp-3528	121	11	the	the	DET
fnp-3528	121	12	most	most	ADV
fnp-3528	121	13	genuine	genuine	ADJ
fnp-3528	121	14	interactors	interactor	NOUN
fnp-3528	121	15	of	of	ADP
fnp-3528	121	16	abca	abca	NOUN
fnp-3528	121	17	transporters	transporter	NOUN
fnp-3528	121	18	are	be	AUX
fnp-3528	121	19	intrinsic	intrinsic	ADJ
fnp-3528	121	20	substrates	substrate	NOUN
fnp-3528	121	21	of	of	ADP
fnp-3528	121	22	these	these	DET
fnp-3528	121	23	transporters	transporter	NOUN
fnp-3528	121	24	.	.	PUNCT
fnp-3528	122	1	these	these	PRON
fnp-3528	122	2	include	include	VERB
fnp-3528	122	3	cholesterol	cholesterol	NOUN
fnp-3528	122	4	(	(	PUNCT
fnp-3528	122	5	figure	figure	NOUN
fnp-3528	122	6	 	 	SPACE
fnp-3528	122	7	1	1	NUM
fnp-3528	122	8	)	)	PUNCT
fnp-3528	122	9	and	and	CCONJ
fnp-3528	122	10	other	other	ADJ
fnp-3528	122	11	sterol	sterol	NOUN
fnp-3528	122	12	derivatives,10,221,222,228	derivatives,10,221,222,228	PROPN
fnp-3528	122	13	but	but	CCONJ
fnp-3528	122	14	also	also	ADV
fnp-3528	122	15	phospholipids	phospholipid	NOUN
fnp-3528	122	16	(	(	PUNCT
fnp-3528	122	17	figure	figure	NOUN
fnp-3528	122	18	 	 	SPACE
fnp-3528	122	19	1	1	NUM
fnp-3528	122	20	)	)	PUNCT
fnp-3528	122	21	,	,	PUNCT
fnp-3528	122	22	sphingolipids228,229	sphingolipids228,229	NOUN
fnp-3528	122	23	and	and	CCONJ
fnp-3528	122	24	retinoids	retinoid	NOUN
fnp-3528	122	25	(	(	PUNCT
fnp-3528	122	26	e.g.	e.g.	ADV
fnp-3528	122	27	,	,	PUNCT
fnp-3528	122	28	all	all	DET
fnp-3528	122	29	-	-	PUNCT
fnp-3528	122	30	trans	trans	NOUN
fnp-3528	122	31	-	-	ADJ
fnp-3528	122	32	retinal	retinal	ADJ
fnp-3528	122	33	;	;	PUNCT
fnp-3528	122	34	figure	figure	NOUN
fnp-3528	122	35	 	 	SPACE
fnp-3528	122	36	1).133	1).133	NUM
fnp-3528	122	37	-	-	SYM
fnp-3528	122	38	138	138	NUM
fnp-3528	122	39	in	in	ADP
fnp-3528	122	40	addition	addition	NOUN
fnp-3528	122	41	,	,	PUNCT
fnp-3528	122	42	certain	certain	ADJ
fnp-3528	122	43	intrinsic	intrinsic	ADJ
fnp-3528	122	44	molecules	molecule	NOUN
fnp-3528	122	45	were	be	AUX
fnp-3528	122	46	demonstrated	demonstrate	VERB
fnp-3528	122	47	to	to	PART
fnp-3528	122	48	interact	interact	VERB
fnp-3528	122	49	with	with	ADP
fnp-3528	122	50	abca	abca	PROPN
fnp-3528	122	51	transporters	transporter	NOUN
fnp-3528	122	52	,	,	PUNCT
fnp-3528	122	53	in	in	ADP
fnp-3528	122	54	particular	particular	ADJ
fnp-3528	122	55	with	with	ADP
fnp-3528	122	56	abca1230	abca1230	PROPN
fnp-3528	122	57	and	and	CCONJ
fnp-3528	122	58	abca8.10,221,222	abca8.10,221,222	NOUN
fnp-3528	122	59	α	α	NOUN
fnp-3528	122	60	-	-	NOUN
fnp-3528	122	61	tocopherol	tocopherol	NOUN
fnp-3528	122	62	(	(	PUNCT
fnp-3528	122	63	vitamin	vitamin	NOUN
fnp-3528	122	64	e	e	NOUN
fnp-3528	122	65	)	)	PUNCT
fnp-3528	122	66	was	be	AUX
fnp-3528	122	67	demonstrated	demonstrate	VERB
fnp-3528	122	68	to	to	PART
fnp-3528	122	69	be	be	AUX
fnp-3528	122	70	transported	transport	VERB
fnp-3528	122	71	by	by	ADP
fnp-3528	122	72	abca1,230	abca1,230	PROPN
fnp-3528	122	73	and	and	CCONJ
fnp-3528	122	74	to	to	PART
fnp-3528	122	75	interfere	interfere	VERB
fnp-3528	122	76	with	with	ADP
fnp-3528	122	77	abca1	abca1	NOUN
fnp-3528	122	78	regulation.231	regulation.231	VERB
fnp-3528	122	79	the	the	DET
fnp-3528	122	80	sterol	sterol	NOUN
fnp-3528	122	81	derivatives	derivative	NOUN
fnp-3528	122	82	estradiol	estradiol	PROPN
fnp-3528	122	83	-	-	PUNCT
fnp-3528	122	84	β	β	NOUN
fnp-3528	122	85	-	-	ADJ
fnp-3528	122	86	glucuronide	glucuronide	ADJ
fnp-3528	122	87	,	,	PUNCT
fnp-3528	122	88	estrone	estrone	NOUN
fnp-3528	122	89	sulfate	sulfate	NOUN
fnp-3528	122	90	,	,	PUNCT
fnp-3528	122	91	and	and	CCONJ
fnp-3528	122	92	taurocholic	taurocholic	ADJ
fnp-3528	122	93	acid	acid	NOUN
fnp-3528	122	94	(	(	PUNCT
fnp-3528	122	95	figure	figure	NOUN
fnp-3528	122	96	 	 	SPACE
fnp-3528	122	97	1	1	NUM
fnp-3528	122	98	)	)	PUNCT
fnp-3528	122	99	,	,	PUNCT
fnp-3528	122	100	but	but	CCONJ
fnp-3528	122	101	also	also	ADV
fnp-3528	122	102	the	the	DET
fnp-3528	122	103	physiological	physiological	ADJ
fnp-3528	122	104	substrate	substrate	NOUN
fnp-3528	122	105	leukotriene	leukotriene	NOUN
fnp-3528	122	106	c4	c4	NOUN
fnp-3528	122	107	(	(	PUNCT
fnp-3528	122	108	ltc4	ltc4	PROPN
fnp-3528	122	109	)	)	PUNCT
fnp-3528	122	110	,	,	PUNCT
fnp-3528	122	111	the	the	DET
fnp-3528	122	112	natural	natural	ADJ
fnp-3528	122	113	compound	compound	NOUN
fnp-3528	122	114	ochratoxin	ochratoxin	NOUN
fnp-3528	122	115	a	a	PRON
fnp-3528	122	116	,	,	PUNCT
fnp-3528	122	117	as	as	ADV
fnp-3528	122	118	well	well	ADV
fnp-3528	122	119	as	as	ADP
fnp-3528	122	120	the	the	DET
fnp-3528	122	121	chemical	chemical	NOUN
fnp-3528	122	122	p	p	ADJ
fnp-3528	122	123	-	-	PUNCT
fnp-3528	122	124	amino	amino	NOUN
fnp-3528	122	125	hippuric	hippuric	ADJ
fnp-3528	122	126	acid	acid	NOUN
fnp-3528	122	127	were	be	AUX
fnp-3528	122	128	discovered	discover	VERB
fnp-3528	122	129	as	as	ADP
fnp-3528	122	130	(	(	PUNCT
fnp-3528	122	131	potential	potential	ADJ
fnp-3528	122	132	)	)	PUNCT
fnp-3528	122	133	abca8	abca8	NOUN
fnp-3528	122	134	substrates.10,221,222	substrates.10,221,222	NOUN
fnp-3528	122	135	specifically	specifically	ADV
fnp-3528	122	136	the	the	DET
fnp-3528	122	137	abca8	abca8	ADV
fnp-3528	122	138	-	-	PUNCT
fnp-3528	122	139	mediated	mediate	VERB
fnp-3528	122	140	taurocholate	taurocholate	NOUN
fnp-3528	122	141	export	export	NOUN
fnp-3528	122	142	from	from	ADP
fnp-3528	122	143	various	various	ADJ
fnp-3528	122	144	human	human	ADJ
fnp-3528	122	145	pancreatic	pancreatic	ADJ
fnp-3528	122	146	cancer	cancer	NOUN
fnp-3528	122	147	cell	cell	NOUN
fnp-3528	122	148	lines	line	NOUN
fnp-3528	122	149	was	be	AUX
fnp-3528	122	150	suggested	suggest	VERB
fnp-3528	122	151	as	as	ADP
fnp-3528	122	152	the	the	DET
fnp-3528	122	153	major	major	ADJ
fnp-3528	122	154	mechanism	mechanism	NOUN
fnp-3528	122	155	behind	behind	ADP
fnp-3528	122	156	gemcitabine	gemcitabine	NOUN
fnp-3528	122	157	resistance	resistance	NOUN
fnp-3528	122	158	in	in	ADP
fnp-3528	122	159	these	these	DET
fnp-3528	122	160	cells,221	cells,221	NOUN
fnp-3528	122	161	which	which	PRON
fnp-3528	122	162	was	be	AUX
fnp-3528	122	163	corroborated	corroborate	VERB
fnp-3528	122	164	in	in	ADP
fnp-3528	122	165	hek293	hek293	PROPN
fnp-3528	122	166	cells	cell	NOUN
fnp-3528	122	167	stably	stably	ADV
fnp-3528	122	168	expressing	express	VERB
fnp-3528	122	169	abca8.10	abca8.10	ADP
fnp-3528	122	170	in	in	ADP
fnp-3528	122	171	addition	addition	NOUN
fnp-3528	122	172	,	,	PUNCT
fnp-3528	122	173	a	a	DET
fnp-3528	122	174	small	small	ADJ
fnp-3528	122	175	body	body	NOUN
fnp-3528	122	176	of	of	ADP
fnp-3528	122	177	evidence	evidence	NOUN
fnp-3528	122	178	suggests	suggest	VERB
fnp-3528	122	179	that	that	SCONJ
fnp-3528	122	180	abca2	abca2	NOUN
fnp-3528	122	181	and	and	CCONJ
fnp-3528	122	182	abca3	abca3	PROPN
fnp-3528	122	183	contribute	contribute	VERB
fnp-3528	122	184	to	to	ADP
fnp-3528	122	185	the	the	DET
fnp-3528	122	186	subcellular	subcellular	ADJ
fnp-3528	122	187	sequestration	sequestration	NOUN
fnp-3528	122	188	of	of	ADP
fnp-3528	122	189	certain	certain	ADJ
fnp-3528	122	190	antineoplastic	antineoplastic	ADJ
fnp-3528	122	191	agents	agent	NOUN
fnp-3528	122	192	into	into	ADP
fnp-3528	122	193	endoand	endoand	PROPN
fnp-3528	122	194	lysosomes.232	lysosomes.232	PROPN
fnp-3528	122	195	-	-	PUNCT
fnp-3528	122	196	235	235	NUM
fnp-3528	122	197	these	these	DET
fnp-3528	122	198	agents	agent	NOUN
fnp-3528	122	199	include	include	VERB
fnp-3528	122	200	cytarabine	cytarabine	NOUN
fnp-3528	122	201	(	(	PUNCT
fnp-3528	122	202	abca3),235	abca3),235	NUM
fnp-3528	122	203	daunorubicin	daunorubicin	NOUN
fnp-3528	122	204	(	(	PUNCT
fnp-3528	122	205	abca3),232,233,235	abca3),232,233,235	VERB
fnp-3528	122	206	etoposide	etoposide	NOUN
fnp-3528	122	207	(	(	PUNCT
fnp-3528	122	208	abca3),235	abca3),235	PROPN
fnp-3528	122	209	imatinib	imatinib	NOUN
fnp-3528	122	210	(	(	PUNCT
fnp-3528	122	211	abca2	abca2	NOUN
fnp-3528	122	212	and	and	CCONJ
fnp-3528	122	213	abca3	abca3	PROPN
fnp-3528	122	214	;	;	PUNCT
fnp-3528	122	215	figure	figure	NOUN
fnp-3528	122	216	 	 	SPACE
fnp-3528	122	217	1),234,236	1),234,236	NUM
fnp-3528	122	218	mitoxantrone	mitoxantrone	NOUN
fnp-3528	122	219	(	(	PUNCT
fnp-3528	122	220	abca3),235	abca3),235	NUM
fnp-3528	122	221	and	and	CCONJ
fnp-3528	122	222	vincristine	vincristine	NOUN
fnp-3528	122	223	(	(	PUNCT
fnp-3528	122	224	abca3	abca3	PROPN
fnp-3528	122	225	;	;	PUNCT
fnp-3528	122	226	figure	figure	NOUN
fnp-3528	122	227	 	 	SPACE
fnp-3528	122	228	1).235	1).235	NOUN
fnp-3528	122	229	furthermore	furthermore	ADV
fnp-3528	122	230	,	,	PUNCT
fnp-3528	122	231	several	several	ADJ
fnp-3528	122	232	antineoplastic	antineoplastic	ADJ
fnp-3528	122	233	agents	agent	NOUN
fnp-3528	122	234	were	be	AUX
fnp-3528	122	235	described	describe	VERB
fnp-3528	122	236	to	to	PART
fnp-3528	122	237	have	have	VERB
fnp-3528	122	238	less	less	ADJ
fnp-3528	122	239	effect	effect	NOUN
fnp-3528	122	240	when	when	SCONJ
fnp-3528	122	241	abca2	abca2	PROPN
fnp-3528	122	242	was	be	AUX
fnp-3528	122	243	overexpressed	overexpresse	VERB
fnp-3528	122	244	in	in	ADP
fnp-3528	122	245	vitro171,237,238	vitro171,237,238	NOUN
fnp-3528	122	246	and	and	CCONJ
fnp-3528	122	247	in	in	ADP
fnp-3528	122	248	vivo.239	vivo.239	NOUN
fnp-3528	122	249	for	for	ADP
fnp-3528	122	250	example	example	NOUN
fnp-3528	122	251	,	,	PUNCT
fnp-3528	122	252	the	the	DET
fnp-3528	122	253	anticancer	anticancer	NOUN
fnp-3528	122	254	drug	drug	NOUN
fnp-3528	122	255	estramustine	estramustine	PROPN
fnp-3528	122	256	(	(	PUNCT
fnp-3528	122	257	figure	figure	NOUN
fnp-3528	122	258	 	 	SPACE
fnp-3528	122	259	1	1	NUM
fnp-3528	122	260	)	)	PUNCT
fnp-3528	122	261	was	be	AUX
fnp-3528	122	262	effluxed	effluxe	VERB
fnp-3528	122	263	from	from	ADP
fnp-3528	122	264	abca2	abca2	NOUN
fnp-3528	122	265	-	-	PUNCT
fnp-3528	122	266	overexpressing	overexpresse	VERB
fnp-3528	122	267	human	human	ADJ
fnp-3528	122	268	ovary	ovary	ADJ
fnp-3528	122	269	carcinoma	carcinoma	NOUN
fnp-3528	122	270	cells	cell	NOUN
fnp-3528	122	271	,	,	PUNCT
fnp-3528	122	272	which	which	PRON
fnp-3528	122	273	were	be	AUX
fnp-3528	122	274	less	less	ADV
fnp-3528	122	275	susceptible	susceptible	ADJ
fnp-3528	122	276	to	to	PART
fnp-3528	122	277	estramustine	estramustine	VERB
fnp-3528	122	278	treatment	treatment	NOUN
fnp-3528	122	279	than	than	ADP
fnp-3528	122	280	the	the	DET
fnp-3528	122	281	sensitive	sensitive	ADJ
fnp-3528	122	282	cell	cell	NOUN
fnp-3528	122	283	line.171,238	line.171,238	NOUN
fnp-3528	122	284	antisense	antisense	NOUN
fnp-3528	122	285	nucleotide	nucleotide	ADJ
fnp-3528	122	286	treatment	treatment	NOUN
fnp-3528	122	287	against	against	ADP
fnp-3528	122	288	abca2	abca2	NOUN
fnp-3528	122	289	re	re	VERB
fnp-3528	122	290	-	-	VERB
fnp-3528	122	291	sensitized	sensitize	VERB
fnp-3528	122	292	the	the	DET
fnp-3528	122	293	carcinoma	carcinoma	NOUN
fnp-3528	122	294	cells	cell	NOUN
fnp-3528	122	295	,	,	PUNCT
fnp-3528	122	296	further	far	ADV
fnp-3528	122	297	demonstrating	demonstrate	VERB
fnp-3528	122	298	a	a	DET
fnp-3528	122	299	role	role	NOUN
fnp-3528	122	300	for	for	ADP
fnp-3528	122	301	abca2	abca2	NOUN
fnp-3528	122	302	in	in	ADP
fnp-3528	122	303	mediating	mediate	VERB
fnp-3528	122	304	drug	drug	NOUN
fnp-3528	122	305	efflux.238	efflux.238	NOUN
fnp-3528	122	306	furthermore	furthermore	ADV
fnp-3528	122	307	,	,	PUNCT
fnp-3528	122	308	abca2	abca2	NOUN
fnp-3528	122	309	knock	knock	VERB
fnp-3528	122	310	-	-	PUNCT
fnp-3528	122	311	out	out	ADP
fnp-3528	122	312	mice	mouse	NOUN
fnp-3528	122	313	had	have	AUX
fnp-3528	122	314	elevated	elevate	VERB
fnp-3528	122	315	estradiol	estradiol	PROPN
fnp-3528	122	316	and	and	CCONJ
fnp-3528	122	317	estrone	estrone	NOUN
fnp-3528	122	318	levels	level	NOUN
fnp-3528	122	319	when	when	SCONJ
fnp-3528	122	320	treated	treat	VERB
fnp-3528	122	321	with	with	ADP
fnp-3528	122	322	estramustine.239	estramustine.239	PROPN
fnp-3528	122	323	a	a	DET
fnp-3528	122	324	similar	similar	ADJ
fnp-3528	122	325	effect	effect	NOUN
fnp-3528	122	326	in	in	ADP
fnp-3528	122	327	terms	term	NOUN
fnp-3528	122	328	of	of	ADP
fnp-3528	122	329	susceptibility	susceptibility	NOUN
fnp-3528	122	330	and	and	CCONJ
fnp-3528	122	331	re	re	NOUN
fnp-3528	122	332	-	-	NOUN
fnp-3528	122	333	sensitization	sensitization	NOUN
fnp-3528	122	334	was	be	AUX
fnp-3528	122	335	observed	observe	VERB
fnp-3528	122	336	for	for	ADP
fnp-3528	122	337	abca3	abca3	NOUN
fnp-3528	122	338	-	-	PUNCT
fnp-3528	122	339	mediated	mediate	VERB
fnp-3528	122	340	transport	transport	NOUN
fnp-3528	122	341	of	of	ADP
fnp-3528	122	342	miltefosine	miltefosine	NOUN
fnp-3528	122	343	in	in	ADP
fnp-3528	122	344	leishmania,240	leishmania,240	NOUN
fnp-3528	122	345	doxorubicin	doxorubicin	PROPN
fnp-3528	122	346	resistance	resistance	NOUN
fnp-3528	122	347	in	in	ADP
fnp-3528	122	348	acute	acute	ADJ
fnp-3528	122	349	myeloid	myeloid	NOUN
fnp-3528	122	350	leukemia	leukemia	PROPN
fnp-3528	122	351	cells,237	cells,237	PROPN
fnp-3528	122	352	and	and	CCONJ
fnp-3528	122	353	cisplatin	cisplatin	NOUN
fnp-3528	122	354	as	as	ADV
fnp-3528	122	355	well	well	ADV
fnp-3528	122	356	as	as	ADP
fnp-3528	122	357	paclitaxel	paclitaxel	VERB
fnp-3528	122	358	resistance	resistance	NOUN
fnp-3528	122	359	in	in	ADP
fnp-3528	122	360	several	several	ADJ
fnp-3528	122	361	lung	lung	NOUN
fnp-3528	122	362	cancer	cancer	NOUN
fnp-3528	122	363	cell	cell	NOUN
fnp-3528	122	364	lines.241	lines.241	NOUN
fnp-3528	122	365	table	table	NOUN
fnp-3528	122	366	2	2	NUM
fnp-3528	122	367	.	.	PUNCT
fnp-3528	122	368	currently	currently	ADV
fnp-3528	122	369	known	know	VERB
fnp-3528	122	370	modulators	modulator	NOUN
fnp-3528	122	371	of	of	ADP
fnp-3528	122	372	abca1	abca1	NOUN
fnp-3528	122	373	.	.	PUNCT
fnp-3528	123	1	mode	mode	NOUN
fnp-3528	123	2	of	of	ADP
fnp-3528	123	3	modulation	modulation	NOUN
fnp-3528	123	4	name	name	NOUN
fnp-3528	123	5	of	of	ADP
fnp-3528	123	6	modulator	modulator	NOUN
fnp-3528	123	7	effect	effect	NOUN
fnp-3528	123	8	concentration	concentration	NOUN
fnp-3528	123	9	;	;	PUNCT
fnp-3528	123	10	concentration	concentration	NOUN
fnp-3528	123	11	range	range	NOUN
fnp-3528	123	12	;	;	PUNCT
fnp-3528	124	1	ec50	ec50	PROPN
fnp-3528	124	2	;	;	PUNCT
fnp-3528	124	3	dose	dose	VERB
fnp-3528	124	4	;	;	PUNCT
fnp-3528	124	5	ed50	ed50	PROPN
fnp-3528	124	6	(	(	PUNCT
fnp-3528	124	7	potential	potential	ADJ
fnp-3528	124	8	)	)	PUNCT
fnp-3528	124	9	substrates	substrate	VERB
fnp-3528	124	10	cholesterol	cholesterol	NOUN
fnp-3528	124	11	phospholipids	phospholipid	NOUN
fnp-3528	124	12	β	β	NOUN
fnp-3528	124	13	-	-	NOUN
fnp-3528	124	14	sitosterol	sitosterol	VERB
fnp-3528	124	15	sphingomyelin	sphingomyelin	NOUN
fnp-3528	124	16	α	α	PROPN
fnp-3528	124	17	-	-	PUNCT
fnp-3528	124	18	tocopherol	tocopherol	NOUN
fnp-3528	124	19	activators	activator	NOUN
fnp-3528	124	20	ati-5261	ati-5261	VERB
fnp-3528	124	21	cs-6253	cs-6253	VERB
fnp-3528	124	22	1.07	1.07	NUM
fnp-3528	124	23	µm	µm	NOUN
fnp-3528	124	24	;	;	PUNCT
fnp-3528	124	25	30	30	NUM
fnp-3528	124	26	mg	mg	PROPN
fnp-3528	124	27	/	/	SYM
fnp-3528	124	28	kg	kg	PROPN
fnp-3528	124	29	body	body	NOUN
fnp-3528	124	30	weight	weight	NOUN
fnp-3528	124	31	in	in	ADP
fnp-3528	124	32	mice	mice	NOUN
fnp-3528	124	33	0.73	0.73	NUM
fnp-3528	124	34	µm	µm	NOUN
fnp-3528	124	35	;	;	PUNCT
fnp-3528	124	36	20	20	NUM
fnp-3528	124	37	mg	mg	NUM
fnp-3528	124	38	/	/	SYM
fnp-3528	124	39	kg	kg	PROPN
fnp-3528	124	40	body	body	NOUN
fnp-3528	124	41	weight	weight	NOUN
fnp-3528	124	42	in	in	ADP
fnp-3528	124	43	mice	mice	NOUN
fnp-3528	124	44	inhibitors	inhibitor	NOUN
fnp-3528	124	45	blt-4	blt-4	ADV
fnp-3528	124	46	bromosulfophthaleine	bromosulfophthaleine	VERB
fnp-3528	124	47	bumetanide	bumetanide	ADJ
fnp-3528	124	48	cyclosporine	cyclosporine	NOUN
fnp-3528	124	49	a	a	DET
fnp-3528	124	50	dids	did	NOUN
fnp-3528	124	51	diphenylamine	diphenylamine	NOUN
fnp-3528	124	52	2	2	NUM
fnp-3528	124	53	-	-	PUNCT
fnp-3528	124	54	carboxylic	carboxylic	ADJ
fnp-3528	124	55	acid	acid	NOUN
fnp-3528	124	56	flufenamic	flufenamic	ADJ
fnp-3528	124	57	acid	acid	NOUN
fnp-3528	124	58	furosemide	furosemide	NOUN
fnp-3528	124	59	glibenclamide	glibenclamide	NOUN
fnp-3528	124	60	pimecrolimus	pimecrolimus	PROPN
fnp-3528	124	61	probucol	probucol	PROPN
fnp-3528	124	62	sirolimus	sirolimus	PROPN
fnp-3528	124	63	tacrolimus	tacrolimus	PROPN
fnp-3528	124	64	valspodar	valspodar	PROPN
fnp-3528	124	65	150	150	NUM
fnp-3528	124	66	µm	µm	ADP
fnp-3528	124	67	500	500	NUM
fnp-3528	124	68	µm	µm	ADP
fnp-3528	124	69	200	200	NUM
fnp-3528	124	70	µm	µm	ADP
fnp-3528	124	71	1–20	1–20	PROPN
fnp-3528	124	72	µm	µm	ADP
fnp-3528	124	73	;	;	PUNCT
fnp-3528	125	1	ic50	ic50	PROPN
fnp-3528	125	2	=	=	PUNCT
fnp-3528	125	3	5.1–7.6	5.1–7.6	NUM
fnp-3528	125	4	µm	µm	ADP
fnp-3528	125	5	40–500	40–500	NUM
fnp-3528	125	6	µm	µm	ADP
fnp-3528	125	7	500	500	NUM
fnp-3528	125	8	µm	µm	ADP
fnp-3528	125	9	500	500	NUM
fnp-3528	125	10	µm	µm	ADP
fnp-3528	125	11	200	200	NUM
fnp-3528	125	12	µm	µm	PART
fnp-3528	125	13	50–1000	50–1000	NUM
fnp-3528	125	14	µm	µm	ADP
fnp-3528	125	15	20	20	NUM
fnp-3528	125	16	µm	µm	NUM
fnp-3528	125	17	;	;	PUNCT
fnp-3528	125	18	ic50	ic50	PROPN
fnp-3528	125	19	=	=	PROPN
fnp-3528	126	1	7.0	7.0	NUM
fnp-3528	126	2	µm	µm	NUM
fnp-3528	126	3	1.9–20	1.9–20	NUM
fnp-3528	126	4	µm	µm	ADP
fnp-3528	126	5	20	20	NUM
fnp-3528	126	6	µm	µm	NUM
fnp-3528	126	7	;	;	PUNCT
fnp-3528	126	8	ic50	ic50	PROPN
fnp-3528	126	9	=	=	PROPN
fnp-3528	126	10	18.8	18.8	NUM
fnp-3528	126	11	µm	µm	PART
fnp-3528	126	12	20	20	NUM
fnp-3528	126	13	µm	µm	NUM
fnp-3528	126	14	;	;	PUNCT
fnp-3528	126	15	ic50	ic50	PROPN
fnp-3528	126	16	=	=	PUNCT
fnp-3528	126	17	13.6	13.6	NUM
fnp-3528	126	18	µm	µm	ADP
fnp-3528	126	19	5	5	NUM
fnp-3528	126	20	µm	µm	NOUN
fnp-3528	126	21	;	;	PUNCT
fnp-3528	126	22	ic50	ic50	PROPN
fnp-3528	126	23	=	=	PROPN
fnp-3528	126	24	1.9	1.9	NUM
fnp-3528	126	25	µm	µm	ADP
fnp-3528	126	26	inducers	inducer	NOUN
fnp-3528	126	27	a-769662	a-769662	PUNCT
fnp-3528	126	28	aclarubicin	aclarubicin	ADJ
fnp-3528	126	29	allicin	allicin	NOUN
fnp-3528	126	30	camp	camp	NOUN
fnp-3528	126	31	butyryl	butyryl	NOUN
fnp-3528	126	32	-	-	PUNCT
fnp-3528	126	33	camp	camp	NOUN
fnp-3528	126	34	8	8	NUM
fnp-3528	126	35	-	-	PUNCT
fnp-3528	126	36	br	br	ADP
fnp-3528	126	37	-	-	PUNCT
fnp-3528	126	38	camp	camp	NOUN
fnp-3528	126	39	cpt	cpt	PROPN
fnp-3528	126	40	-	-	PUNCT
fnp-3528	126	41	camp	camp	NOUN
fnp-3528	126	42	atorvastatin	atorvastatin	PROPN
fnp-3528	126	43	atra	atra	PROPN
fnp-3528	126	44	az1	az1	PROPN
fnp-3528	126	45	–	–	PUNCT
fnp-3528	126	46	az9	az9	NOUN
fnp-3528	126	47	az-1	az-1	NOUN
fnp-3528	126	48	az-2	az-2	ADP
fnp-3528	126	49	az10606120	az10606120	PROPN
fnp-3528	126	50	az876	az876	PROPN
fnp-3528	126	51	bcd1	bcd1	PROPN
fnp-3528	126	52	n	n	CCONJ
fnp-3528	126	53	-	-	PUNCT
fnp-3528	126	54	benzothiazolyl-2	benzothiazolyl-2	VERB
fnp-3528	126	55	-	-	PUNCT
fnp-3528	126	56	benzenesulfonamides	benzenesulfonamide	NOUN
fnp-3528	126	57	berberine	berberine	NOUN
fnp-3528	126	58	bergapten	bergapten	NOUN
fnp-3528	126	59	bexarotene	bexarotene	PROPN
fnp-3528	126	60	bezafibrate	bezafibrate	PROPN
fnp-3528	126	61	bms-852927	bms-852927	PROPN
fnp-3528	126	62	sodium	sodium	NOUN
fnp-3528	126	63	-	-	PUNCT
fnp-3528	126	64	butyrate	butyrate	NOUN
fnp-3528	126	65	cholesterol	cholesterol	NOUN
fnp-3528	126	66	cholic	cholic	NOUN
fnp-3528	126	67	acid	acid	NOUN
fnp-3528	126	68	analog	analog	NOUN
fnp-3528	126	69	14b	14b	NUM
fnp-3528	126	70	celastrol	celastrol	NOUN
fnp-3528	126	71	chalcone	chalcone	NOUN
fnp-3528	126	72	derivatives	derivative	NOUN
fnp-3528	126	73	chromene	chromene	VERB
fnp-3528	126	74	derivatives	derivative	NOUN
fnp-3528	126	75	2	2	NUM
fnp-3528	126	76	,	,	PUNCT
fnp-3528	126	77	3	3	NUM
fnp-3528	126	78	,	,	PUNCT
fnp-3528	126	79	and	and	CCONJ
fnp-3528	126	80	5	5	NUM
fnp-3528	126	81	chromone	chromone	NOUN
fnp-3528	126	82	analog	analog	NOUN
fnp-3528	126	83	6	6	NUM
fnp-3528	126	84	cl2	cl2	NOUN
fnp-3528	126	85	-	-	SYM
fnp-3528	126	86	57	57	NUM
fnp-3528	126	87	curcumin	curcumin	NOUN
fnp-3528	126	88	daidzein	daidzein	PROPN
fnp-3528	126	89	danthron	danthron	PROPN
fnp-3528	126	90	1,6	1,6	NUM
fnp-3528	126	91	-	-	PUNCT
fnp-3528	126	92	o	o	NOUN
fnp-3528	126	93	,	,	PUNCT
fnp-3528	126	94	o	o	ADJ
fnp-3528	126	95	-	-	PUNCT
fnp-3528	126	96	diacetylbritannilactone	diacetylbritannilactone	ADJ
fnp-3528	126	97	digoxin	digoxin	NOUN
fnp-3528	126	98	doxazosin	doxazosin	PROPN
fnp-3528	126	99	doxorubicin	doxorubicin	PROPN
fnp-3528	126	100	efatutazone	efatutazone	PROPN
fnp-3528	126	101	e3317	e3317	ADJ
fnp-3528	126	102	egcg	egcg	NOUN
fnp-3528	126	103	homo	homo	PROPN
fnp-3528	126	104	-	-	PUNCT
fnp-3528	126	105	eriodictyol	eriodictyol	NOUN
fnp-3528	126	106	ethyl	ethyl	PROPN
fnp-3528	126	107	2,4,6	2,4,6	PROPN
fnp-3528	126	108	-	-	PUNCT
fnp-3528	126	109	trihydroxybenzoate	trihydroxybenzoate	NOUN
fnp-3528	126	110	f1	f1	NOUN
fnp-3528	126	111	f4	f4	PROPN
fnp-3528	126	112	fargesin	fargesin	NOUN
fnp-3528	126	113	fenofibrate	fenofibrate	NOUN
fnp-3528	126	114	fluvastatin	fluvastatin	PROPN
fnp-3528	126	115	fpd5	fpd5	PROPN
fnp-3528	126	116	fucosterol	fucosterol	PROPN
fnp-3528	126	117	geniposide	geniposide	ADV
fnp-3528	126	118	ginsenoside	ginsenoside	ADV
fnp-3528	126	119	(	(	PUNCT
fnp-3528	126	120	derivatives	derivative	NOUN
fnp-3528	126	121	)	)	PUNCT
fnp-3528	126	122	ginsenoside	ginsenoside	NOUN
fnp-3528	126	123	compound	compound	NOUN
fnp-3528	126	124	k	k	PROPN
fnp-3528	126	125	glycyrrhizine	glycyrrhizine	PROPN
fnp-3528	126	126	gq-11	gq-11	PROPN
fnp-3528	126	127	gw3965	gw3965	PROPN
fnp-3528	126	128	gw7845	gw7845	PROPN
fnp-3528	126	129	gypenosides	gypenosides	PROPN
fnp-3528	126	130	hesperetin-7	hesperetin-7	PROPN
fnp-3528	126	131	-	-	PUNCT
fnp-3528	126	132	o	o	NOUN
fnp-3528	126	133	-	-	PUNCT
fnp-3528	126	134	β	β	NOUN
fnp-3528	126	135	-	-	ADJ
fnp-3528	126	136	d	d	NOUN
fnp-3528	126	137	-	-	PUNCT
fnp-3528	126	138	glucopyranoside	glucopyranoside	NOUN
fnp-3528	126	139	hesperetin-7	hesperetin-7	NOUN
fnp-3528	126	140	-	-	PUNCT
fnp-3528	126	141	o	o	NOUN
fnp-3528	126	142	-	-	NOUN
fnp-3528	126	143	rutinosid	rutinosid	ADJ
fnp-3528	126	144	20-(s)-hydroxycholesterol	20-(s)-hydroxycholesterol	NOUN
fnp-3528	126	145	4	4	NUM
fnp-3528	126	146	-	-	PUNCT
fnp-3528	126	147	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	126	148	22-(r)-hydroxycholesterol	22-(r)-hydroxycholesterol	NUM
fnp-3528	126	149	22-(s)-hydroxycholesterol	22-(s)-hydroxycholesterol	NUM
fnp-3528	126	150	24	24	NUM
fnp-3528	126	151	-	-	PUNCT
fnp-3528	126	152	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	126	153	24-(s)-hydroxycholesterol	24-(s)-hydroxycholesterol	NUM
fnp-3528	126	154	25	25	NUM
fnp-3528	126	155	-	-	PUNCT
fnp-3528	126	156	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	126	157	27	27	NUM
fnp-3528	126	158	-	-	PUNCT
fnp-3528	126	159	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	126	160	3	3	NUM
fnp-3528	126	161	-	-	PUNCT
fnp-3528	126	162	hydroxytyrosol	hydroxytyrosol	NOUN
fnp-3528	126	163	idarubicin	idarubicin	PROPN
fnp-3528	126	164	kaempferol	kaempferol	PROPN
fnp-3528	126	165	l836,978	l836,978	ADP
fnp-3528	126	166	kuwanon	kuwanon	PROPN
fnp-3528	126	167	g	g	PROPN
fnp-3528	126	168	l-839,867	l-839,867	PROPN
fnp-3528	126	169	lxr623	lxr623	NOUN
fnp-3528	126	170	lycopene	lycopene	NOUN
fnp-3528	126	171	m2	m2	PROPN
fnp-3528	126	172	maslinic	maslinic	ADJ
fnp-3528	126	173	acid	acid	NOUN
fnp-3528	126	174	metformin	metformin	NOUN
fnp-3528	126	175	mevalonate	mevalonate	VERB
fnp-3528	126	176	mevastatin	mevastatin	PROPN
fnp-3528	126	177	mitotane	mitotane	ADJ
fnp-3528	126	178	naringenin	naringenin	PROPN
fnp-3528	126	179	obeticholic	obeticholic	ADJ
fnp-3528	126	180	acid	acid	PROPN
fnp-3528	126	181	ondansetron	ondansetron	PROPN
fnp-3528	126	182	orlistat	orlistat	PROPN
fnp-3528	126	183	ouabain	ouabain	VERB
fnp-3528	126	184	paeonol	paeonol	ADJ
fnp-3528	126	185	pcb29	pcb29	PROPN
fnp-3528	126	186	-	-	PUNCT
fnp-3528	126	187	pq	pq	PROPN
fnp-3528	126	188	pemafibrate	pemafibrate	NOUN
fnp-3528	126	189	pestalotioquinoside	pestalotioquinoside	PROPN
fnp-3528	126	190	c	c	PROPN
fnp-3528	126	191	phenethyl	phenethyl	PROPN
fnp-3528	126	192	isothiocyanate	isothiocyanate	VERB
fnp-3528	126	193	tadehagi	tadehagi	PROPN
fnp-3528	126	194	triquetrum	triquetrum	ADV
fnp-3528	126	195	-	-	PUNCT
fnp-3528	126	196	derived	derive	VERB
fnp-3528	126	197	glycosides	glycoside	NOUN
fnp-3528	126	198	pioglitazone	pioglitazone	NOUN
fnp-3528	126	199	pitavastatin	pitavastatin	NOUN
fnp-3528	126	200	platycodin	platycodin	VERB
fnp-3528	126	201	d	d	PROPN
fnp-3528	126	202	pma	pma	NOUN
fnp-3528	126	203	ponasterone	ponasterone	NOUN
fnp-3528	126	204	a	a	DET
fnp-3528	126	205	pratensein	pratensein	ADJ
fnp-3528	126	206	propofol	propofol	NOUN
fnp-3528	126	207	prostaglandin	prostaglandin	ADJ
fnp-3528	126	208	j2	j2	PROPN
fnp-3528	126	209	pyrrole	pyrrole	NOUN
fnp-3528	126	210	-	-	PUNCT
fnp-3528	126	211	imidazole	imidazole	NOUN
fnp-3528	126	212	-	-	PUNCT
fnp-3528	126	213	polyamide	polyamide	NOUN
fnp-3528	126	214	pyrromycin	pyrromycin	NOUN
fnp-3528	126	215	quercetin	quercetin	NOUN
fnp-3528	126	216	9	9	NUM
fnp-3528	126	217	-	-	PUNCT
fnp-3528	126	218	cis	cis	NOUN
fnp-3528	126	219	-	-	PUNCT
fnp-3528	126	220	retinoic	retinoic	NOUN
fnp-3528	126	221	acid	acid	NOUN
fnp-3528	126	222	ro0721957/5	ro0721957/5	NOUN
fnp-3528	126	223	ro0264456	ro0264456	NOUN
fnp-3528	126	224	rosiglitazone	rosiglitazone	NOUN
fnp-3528	126	225	rpr-5	rpr-5	PART
fnp-3528	126	226	rutaecarpine	rutaecarpine	NOUN
fnp-3528	126	227	and	and	CCONJ
fnp-3528	126	228	derivatives	derivative	NOUN
fnp-3528	126	229	saikosaponin	saikosaponin	VERB
fnp-3528	126	230	a	a	DET
fnp-3528	126	231	24-(s)-saringosterol	24-(s)-saringosterol	NUM
fnp-3528	126	232	sb203580	sb203580	PROPN
fnp-3528	126	233	scutellarein	scutellarein	ADJ
fnp-3528	126	234	selenium	selenium	NOUN
fnp-3528	126	235	serdemetan	serdemetan	PROPN
fnp-3528	126	236	simvastatin	simvastatin	PROPN
fnp-3528	126	237	spf1	spf1	PROPN
fnp-3528	126	238	spf2	spf2	PROPN
fnp-3528	126	239	soraphene	soraphene	VERB
fnp-3528	126	240	a	a	DET
fnp-3528	126	241	24-(s)-stigmast-5	24-(s)-stigmast-5	NUM
fnp-3528	126	242	-	-	PUNCT
fnp-3528	126	243	ene-3β,24	ene-3β,24	VERB
fnp-3528	126	244	-	-	PUNCT
fnp-3528	126	245	diol	diol	NOUN
fnp-3528	126	246	cannabis	cannabis	NOUN
fnp-3528	126	247	sativa	sativa	NOUN
fnp-3528	126	248	-	-	PUNCT
fnp-3528	126	249	derived	derive	VERB
fnp-3528	126	250	stilbenoids	stilbenoid	NOUN
fnp-3528	126	251	sulfoxaflor	sulfoxaflor	VERB
fnp-3528	126	252	tanshindiol	tanshindiol	NOUN
fnp-3528	126	253	c	c	PROPN
fnp-3528	127	1	taraxasterol	taraxasterol	PRON
fnp-3528	127	2	testosterone	testosterone	NOUN
fnp-3528	127	3	tetradecylthioacetic	tetradecylthioacetic	ADJ
fnp-3528	127	4	acid	acid	NOUN
fnp-3528	127	5	to901317	to901317	PROPN
fnp-3528	127	6	tr1	tr1	PROPN
fnp-3528	127	7	trichostatin	trichostatin	NOUN
fnp-3528	127	8	a	a	DET
fnp-3528	127	9	troglitazone	troglitazone	NOUN
fnp-3528	127	10	ttnpb	ttnpb	NOUN
fnp-3528	127	11	urolithin	urolithin	ADV
fnp-3528	127	12	a	a	DET
fnp-3528	127	13	urolithin	urolithin	PROPN
fnp-3528	127	14	b	b	PROPN
fnp-3528	127	15	urolithin	urolithin	PROPN
fnp-3528	127	16	b	b	PROPN
fnp-3528	127	17	sulfate	sulfate	NOUN
fnp-3528	127	18	vitamin	vitamin	NOUN
fnp-3528	127	19	d3	d3	PROPN
fnp-3528	127	20	vitexin	vitexin	PROPN
fnp-3528	127	21	way-254011	way-254011	PROPN
fnp-3528	128	1	wy14643	wy14643	PROPN
fnp-3528	128	2	bexarotene	bexarotene	PROPN
fnp-3528	128	3	derivatives	derivative	NOUN
fnp-3528	128	4	z10	z10	NOUN
fnp-3528	128	5	and	and	CCONJ
fnp-3528	128	6	z36	z36	PROPN
fnp-3528	128	7	zafirlukast	zafirlukast	NOUN
fnp-3528	128	8	250	250	NUM
fnp-3528	128	9	µm	µm	ADP
fnp-3528	128	10	ec50	ec50	PROPN
fnp-3528	128	11	=	=	PUNCT
fnp-3528	128	12	0.49	0.49	NUM
fnp-3528	128	13	µm	µm	ADP
fnp-3528	128	14	2.5–10	2.5–10	NUM
fnp-3528	128	15	µm	µm	ADP
fnp-3528	128	16	0.1–10	0.1–10	NOUN
fnp-3528	128	17	µm	µm	ADP
fnp-3528	128	18	300	300	NUM
fnp-3528	128	19	µm	µm	ADP
fnp-3528	128	20	0.3–1000	0.3–1000	NUM
fnp-3528	128	21	µm	µm	ADP
fnp-3528	128	22	300–500	300–500	NUM
fnp-3528	128	23	µm	µm	ADP
fnp-3528	128	24	5–10	5–10	PROPN
fnp-3528	128	25	µm	µm	ADP
fnp-3528	128	26	;	;	PUNCT
fnp-3528	128	27	4	4	NUM
fnp-3528	128	28	mg	mg	PROPN
fnp-3528	128	29	/	/	SYM
fnp-3528	128	30	kg	kg	PROPN
fnp-3528	128	31	body	body	NOUN
fnp-3528	128	32	weight	weight	NOUN
fnp-3528	128	33	in	in	ADP
fnp-3528	128	34	mice	mouse	NOUN
fnp-3528	128	35	0.25–10	0.25–10	NOUN
fnp-3528	128	36	µm	µm	ADP
fnp-3528	128	37	ed50	ed50	PROPN
fnp-3528	128	38	=	=	SYM
fnp-3528	128	39	1.49–341	1.49–341	NUM
fnp-3528	128	40	µmol	µmol	NOUN
fnp-3528	128	41	/	/	SYM
fnp-3528	128	42	kg	kg	NOUN
fnp-3528	128	43	body	body	NOUN
fnp-3528	128	44	weight	weight	NOUN
fnp-3528	128	45	in	in	ADP
fnp-3528	128	46	mice	mouse	NOUN
fnp-3528	128	47	10	10	NUM
fnp-3528	128	48	µm	µm	PART
fnp-3528	128	49	10	10	NUM
fnp-3528	128	50	µm	µm	ADP
fnp-3528	128	51	10	10	NUM
fnp-3528	128	52	µm	µm	ADP
fnp-3528	128	53	ed50	ed50	PROPN
fnp-3528	128	54	=	=	PUNCT
fnp-3528	128	55	0.956	0.956	NUM
fnp-3528	128	56	µmol	µmol	PART
fnp-3528	128	57	/	/	SYM
fnp-3528	128	58	kg	kg	NOUN
fnp-3528	128	59	body	body	NOUN
fnp-3528	128	60	weight	weight	NOUN
fnp-3528	128	61	in	in	ADP
fnp-3528	128	62	mice	mouse	NOUN
fnp-3528	128	63	ec50	ec50	PROPN
fnp-3528	128	64	=	=	PUNCT
fnp-3528	128	65	0.035	0.035	NUM
fnp-3528	128	66	µm	µm	ADP
fnp-3528	128	67	ec50	ec50	PROPN
fnp-3528	128	68	=	=	PUNCT
fnp-3528	128	69	0.37–33.42	0.37–33.42	NUM
fnp-3528	128	70	µm	µm	ADP
fnp-3528	128	71	5–20	5–20	PROPN
fnp-3528	128	72	µm	µm	ADP
fnp-3528	128	73	12.5–50.0	12.5–50.0	NUM
fnp-3528	128	74	mg	mg	PROPN
fnp-3528	128	75	/	/	SYM
fnp-3528	128	76	kg	kg	PROPN
fnp-3528	128	77	body	body	NOUN
fnp-3528	128	78	weight	weight	NOUN
fnp-3528	128	79	in	in	ADP
fnp-3528	128	80	rats	rat	NOUN
fnp-3528	128	81	0.1–1	0.1–1	VERB
fnp-3528	128	82	µm	µm	ADP
fnp-3528	128	83	10–200	10–200	NUM
fnp-3528	128	84	µm	µm	ADP
fnp-3528	128	85	ed50	ed50	PROPN
fnp-3528	128	86	=	=	PUNCT
fnp-3528	128	87	2.10	2.10	NUM
fnp-3528	128	88	µmol	µmol	NOUN
fnp-3528	128	89	/	/	SYM
fnp-3528	128	90	kg	kg	NOUN
fnp-3528	128	91	body	body	NOUN
fnp-3528	128	92	weight	weight	NOUN
fnp-3528	128	93	in	in	ADP
fnp-3528	128	94	mice	mouse	NOUN
fnp-3528	128	95	1000–10.000	1000–10.000	NUM
fnp-3528	128	96	µm	µm	ADP
fnp-3528	128	97	;	;	PUNCT
fnp-3528	128	98	200–400	200–400	NUM
fnp-3528	128	99	mg	mg	PROPN
fnp-3528	128	100	/	/	SYM
fnp-3528	128	101	kg	kg	PROPN
fnp-3528	128	102	body	body	NOUN
fnp-3528	128	103	weight	weight	NOUN
fnp-3528	128	104	in	in	ADP
fnp-3528	128	105	mice	mice	NOUN
fnp-3528	128	106	12.9–100	12.9–100	NUM
fnp-3528	128	107	µm	µm	ADP
fnp-3528	128	108	5–40	5–40	NUM
fnp-3528	128	109	µm	µm	ADP
fnp-3528	128	110	0.1–1.0	0.1–1.0	NOUN
fnp-3528	128	111	µm	µm	NOUN
fnp-3528	128	112	;	;	PUNCT
fnp-3528	128	113	0.5–1	0.5–1	PROPN
fnp-3528	128	114	mg	mg	PROPN
fnp-3528	128	115	/	/	SYM
fnp-3528	128	116	kg	kg	PROPN
fnp-3528	128	117	body	body	NOUN
fnp-3528	128	118	weight	weight	NOUN
fnp-3528	128	119	in	in	ADP
fnp-3528	128	120	mice	mouse	NOUN
fnp-3528	128	121	5–10	5–10	PROPN
fnp-3528	128	122	µm	µm	ADP
fnp-3528	128	123	;	;	PUNCT
fnp-3528	128	124	20	20	NUM
fnp-3528	128	125	mg	mg	NUM
fnp-3528	128	126	/	/	SYM
fnp-3528	128	127	kg	kg	PROPN
fnp-3528	128	128	body	body	NOUN
fnp-3528	128	129	weight	weight	NOUN
fnp-3528	128	130	in	in	ADP
fnp-3528	128	131	mice	mouse	NOUN
fnp-3528	128	132	25	25	NUM
fnp-3528	128	133	µm	µm	NUM
fnp-3528	128	134	25	25	NUM
fnp-3528	128	135	µm	µm	ADP
fnp-3528	128	136	10	10	NUM
fnp-3528	128	137	µm	µm	NUM
fnp-3528	128	138	;	;	PUNCT
fnp-3528	128	139	10	10	NUM
fnp-3528	128	140	mg	mg	NUM
fnp-3528	128	141	/	/	SYM
fnp-3528	128	142	kg	kg	PROPN
fnp-3528	128	143	body	body	NOUN
fnp-3528	128	144	weight	weight	NOUN
fnp-3528	128	145	in	in	ADP
fnp-3528	128	146	mice	mouse	NOUN
fnp-3528	128	147	5–40	5–40	NUM
fnp-3528	128	148	µm	µm	ADP
fnp-3528	128	149	ec50	ec50	PROPN
fnp-3528	128	150	=	=	PUNCT
fnp-3528	128	151	3.17	3.17	NUM
fnp-3528	128	152	µm	µm	ADP
fnp-3528	128	153	10–40	10–40	NUM
fnp-3528	128	154	µm	µm	NUM
fnp-3528	128	155	;	;	PUNCT
fnp-3528	128	156	60	60	NUM
fnp-3528	128	157	mg	mg	NUM
fnp-3528	128	158	/	/	SYM
fnp-3528	128	159	kg	kg	NOUN
fnp-3528	128	160	body	body	NOUN
fnp-3528	128	161	weight	weight	NOUN
fnp-3528	128	162	in	in	ADP
fnp-3528	128	163	mice	mice	NOUN
fnp-3528	128	164	8–10	8–10	PROPN
fnp-3528	128	165	µm	µm	NOUN
fnp-3528	128	166	;	;	PUNCT
fnp-3528	128	167	10	10	NUM
fnp-3528	128	168	ml	ml	NOUN
fnp-3528	128	169	/	/	SYM
fnp-3528	128	170	kg	kg	PROPN
fnp-3528	128	171	body	body	NOUN
fnp-3528	128	172	weight	weight	NOUN
fnp-3528	128	173	in	in	ADP
fnp-3528	128	174	mice	mice	NOUN
fnp-3528	128	175	0.010	0.010	NUM
fnp-3528	128	176	µm	µm	ADP
fnp-3528	128	177	10	10	NUM
fnp-3528	128	178	µm	µm	ADP
fnp-3528	128	179	0.0316–1	0.0316–1	NUM
fnp-3528	128	180	µm	µm	ADP
fnp-3528	128	181	;	;	PUNCT
fnp-3528	128	182	20	20	NUM
fnp-3528	128	183	mg	mg	NUM
fnp-3528	128	184	/	/	SYM
fnp-3528	128	185	kg	kg	PROPN
fnp-3528	128	186	body	body	NOUN
fnp-3528	128	187	weight	weight	NOUN
fnp-3528	128	188	in	in	ADP
fnp-3528	128	189	mice	mouse	NOUN
fnp-3528	128	190	40	40	NUM
fnp-3528	128	191	µm	µm	NUM
fnp-3528	128	192	0.01–1	0.01–1	NUM
fnp-3528	128	193	µm	µm	ADP
fnp-3528	128	194	;	;	PUNCT
fnp-3528	128	195	ec50	ec50	PROPN
fnp-3528	128	196	=	=	PUNCT
fnp-3528	128	197	0.2	0.2	NUM
fnp-3528	128	198	µm	µm	NUM
fnp-3528	128	199	40	40	NUM
fnp-3528	128	200	mg	mg	PROPN
fnp-3528	128	201	/	/	SYM
fnp-3528	128	202	kg	kg	PROPN
fnp-3528	128	203	body	body	NOUN
fnp-3528	128	204	weight	weight	NOUN
fnp-3528	128	205	in	in	ADP
fnp-3528	128	206	mice	mouse	NOUN
fnp-3528	128	207	41.4–165	41.4–165	NUM
fnp-3528	128	208	µm	µm	ADP
fnp-3528	128	209	50–100	50–100	NUM
fnp-3528	128	210	µm	µm	ADP
fnp-3528	128	211	ed50	ed50	PROPN
fnp-3528	128	212	=	=	PUNCT
fnp-3528	128	213	10	10	NUM
fnp-3528	128	214	µm	µm	NUM
fnp-3528	128	215	20	20	NUM
fnp-3528	128	216	µm	µm	NUM
fnp-3528	128	217	;	;	PUNCT
fnp-3528	128	218	50	50	NUM
fnp-3528	128	219	mg	mg	PROPN
fnp-3528	128	220	/	/	SYM
fnp-3528	128	221	kg	kg	NOUN
fnp-3528	128	222	body	body	NOUN
fnp-3528	128	223	weight	weight	NOUN
fnp-3528	128	224	in	in	ADP
fnp-3528	128	225	mice	mouse	NOUN
fnp-3528	128	226	2.77–40	2.77–40	NUM
fnp-3528	128	227	µm	µm	ADP
fnp-3528	128	228	1–20	1–20	NOUN
fnp-3528	128	229	µm	µm	ADP
fnp-3528	128	230	1	1	NUM
fnp-3528	128	231	µm	µm	NUM
fnp-3528	128	232	;	;	PUNCT
fnp-3528	128	233	0.005–0.02	0.005–0.02	NOUN
fnp-3528	128	234	mg	mg	PROPN
fnp-3528	128	235	/	/	SYM
fnp-3528	128	236	kg	kg	PROPN
fnp-3528	128	237	body	body	NOUN
fnp-3528	128	238	weight	weight	NOUN
fnp-3528	128	239	in	in	ADP
fnp-3528	128	240	mice	mouse	NOUN
fnp-3528	128	241	100	100	NUM
fnp-3528	128	242	-	-	SYM
fnp-3528	128	243	200	200	NUM
fnp-3528	128	244	µm	µm	ADP
fnp-3528	128	245	515	515	NUM
fnp-3528	128	246	µm	µm	NOUN
fnp-3528	128	247	;	;	PUNCT
fnp-3528	128	248	50–100	50–100	NUM
fnp-3528	128	249	mg	mg	PROPN
fnp-3528	128	250	/	/	SYM
fnp-3528	128	251	kg	kg	PROPN
fnp-3528	128	252	body	body	NOUN
fnp-3528	128	253	weight	weight	NOUN
fnp-3528	128	254	in	in	ADP
fnp-3528	128	255	mice	mouse	NOUN
fnp-3528	128	256	10–30	10–30	NUM
fnp-3528	128	257	µm	µm	ADP
fnp-3528	128	258	1.25	1.25	NUM
fnp-3528	128	259	µm	µm	ADP
fnp-3528	128	260	60.8–243	60.8–243	NUM
fnp-3528	128	261	µm	µm	ADP
fnp-3528	128	262	20	20	NUM
fnp-3528	128	263	mg	mg	NUM
fnp-3528	128	264	/	/	SYM
fnp-3528	128	265	kg	kg	PROPN
fnp-3528	128	266	body	body	NOUN
fnp-3528	128	267	weight	weight	NOUN
fnp-3528	128	268	in	in	ADP
fnp-3528	128	269	mice	mouse	NOUN
fnp-3528	128	270	0.5–50	0.5–50	NOUN
fnp-3528	128	271	µm	µm	ADP
fnp-3528	128	272	;	;	PUNCT
fnp-3528	128	273	ed50	ed50	PROPN
fnp-3528	128	274	=	=	PUNCT
fnp-3528	128	275	0.969	0.969	NUM
fnp-3528	128	276	µmol	µmol	NOUN
fnp-3528	128	277	/	/	SYM
fnp-3528	128	278	kg	kg	NOUN
fnp-3528	128	279	body	body	NOUN
fnp-3528	128	280	weight	weight	NOUN
fnp-3528	128	281	in	in	ADP
fnp-3528	128	282	mice	mouse	NOUN
fnp-3528	128	283	5	5	NUM
fnp-3528	128	284	µm	µm	PART
fnp-3528	128	285	5	5	NUM
fnp-3528	128	286	µg	µg	ADV
fnp-3528	128	287	/	/	SYM
fnp-3528	128	288	ml	ml	ADP
fnp-3528	128	289	107–431	107–431	NUM
fnp-3528	128	290	µm	µm	ADP
fnp-3528	128	291	100	100	NUM
fnp-3528	128	292	µm	µm	NUM
fnp-3528	128	293	;	;	PUNCT
fnp-3528	128	294	3	3	NUM
fnp-3528	128	295	mg	mg	PROPN
fnp-3528	128	296	/	/	SYM
fnp-3528	128	297	kg	kg	PROPN
fnp-3528	128	298	body	body	NOUN
fnp-3528	128	299	weight	weight	NOUN
fnp-3528	128	300	in	in	ADP
fnp-3528	128	301	mice	mice	NOUN
fnp-3528	128	302	5–20	5–20	PROPN
fnp-3528	128	303	µm	µm	ADP
fnp-3528	128	304	1–20	1–20	NOUN
fnp-3528	128	305	µm	µm	ADP
fnp-3528	128	306	1–25	1–25	PROPN
fnp-3528	128	307	µm	µm	NOUN
fnp-3528	128	308	;	;	PUNCT
fnp-3528	129	1	ec50	ec50	PROPN
fnp-3528	129	2	=	=	PROPN
fnp-3528	129	3	1.0	1.0	NUM
fnp-3528	129	4	µm	µm	NUM
fnp-3528	129	5	5–20	5–20	PROPN
fnp-3528	129	6	µm	µm	ADP
fnp-3528	129	7	20	20	NUM
fnp-3528	129	8	µm	µm	ADP
fnp-3528	129	9	0.5–1.5	0.5–1.5	NUM
fnp-3528	129	10	µm	µm	ADP
fnp-3528	129	11	2–12.4	2–12.4	NUM
fnp-3528	129	12	µm	µm	ADP
fnp-3528	129	13	6.21	6.21	NUM
fnp-3528	129	14	µm–10	µm–10	ADP
fnp-3528	129	15	µm	µm	ADP
fnp-3528	129	16	2–5	2–5	NUM
fnp-3528	129	17	µm	µm	ADP
fnp-3528	129	18	0.1	0.1	NUM
fnp-3528	129	19	µm	µm	ADP
fnp-3528	129	20	2.5–10	2.5–10	NUM
fnp-3528	129	21	µm	µm	ADP
fnp-3528	129	22	u.c.a	u.c.a	NOUN
fnp-3528	129	23	20	20	NUM
fnp-3528	129	24	µm	µm	NUM
fnp-3528	129	25	0.1–1	0.1–1	PROPN
fnp-3528	129	26	µm	µm	ADP
fnp-3528	129	27	0.1–1	0.1–1	PROPN
fnp-3528	129	28	µm	µm	ADP
fnp-3528	129	29	;	;	PUNCT
fnp-3528	130	1	ed50	ed50	PROPN
fnp-3528	130	2	=	=	PROPN
fnp-3528	130	3	31.5	31.5	NUM
fnp-3528	130	4	µmol	µmol	NOUN
fnp-3528	130	5	/	/	SYM
fnp-3528	130	6	kg	kg	NOUN
fnp-3528	130	7	body	body	NOUN
fnp-3528	130	8	weight	weight	NOUN
fnp-3528	130	9	in	in	ADP
fnp-3528	130	10	mice	mice	NOUN
fnp-3528	130	11	2.2–6.6	2.2–6.6	NUM
fnp-3528	130	12	mg	mg	PROPN
fnp-3528	130	13	/	/	SYM
fnp-3528	130	14	kg	kg	PROPN
fnp-3528	130	15	body	body	NOUN
fnp-3528	130	16	weight	weight	NOUN
fnp-3528	130	17	in	in	ADP
fnp-3528	130	18	ferrets	ferret	NOUN
fnp-3528	130	19	10	10	NUM
fnp-3528	130	20	µm	µm	PART
fnp-3528	130	21	20	20	NUM
fnp-3528	130	22	µm	µm	ADP
fnp-3528	130	23	10	10	NUM
fnp-3528	130	24	µm	µm	ADP
fnp-3528	130	25	5–500	5–500	NUM
fnp-3528	130	26	µm	µm	ADP
fnp-3528	130	27	50	50	NUM
fnp-3528	130	28	µm	µm	ADP
fnp-3528	130	29	20–50	20–50	NUM
fnp-3528	130	30	µm	µm	ADP
fnp-3528	130	31	25–100	25–100	NUM
fnp-3528	130	32	µm	µm	ADP
fnp-3528	130	33	40	40	NUM
fnp-3528	130	34	mg	mg	PROPN
fnp-3528	130	35	/	/	SYM
fnp-3528	130	36	kg	kg	PROPN
fnp-3528	130	37	body	body	NOUN
fnp-3528	130	38	weight	weight	NOUN
fnp-3528	130	39	in	in	ADP
fnp-3528	130	40	mice	mouse	NOUN
fnp-3528	130	41	1	1	NUM
fnp-3528	130	42	µm	µm	ADP
fnp-3528	130	43	50	50	NUM
fnp-3528	130	44	µm	µm	ADP
fnp-3528	130	45	0.010	0.010	NUM
fnp-3528	130	46	µm	µm	ADP
fnp-3528	130	47	100	100	NUM
fnp-3528	130	48	µm	µm	ADP
fnp-3528	130	49	5–10	5–10	NOUN
fnp-3528	130	50	µm	µm	ADP
fnp-3528	130	51	0.1–10	0.1–10	NOUN
fnp-3528	130	52	µm	µm	ADP
fnp-3528	130	53	;	;	PUNCT
fnp-3528	130	54	0.3	0.3	NUM
fnp-3528	130	55	mg	mg	PROPN
fnp-3528	130	56	/	/	SYM
fnp-3528	130	57	kg	kg	PROPN
fnp-3528	130	58	body	body	NOUN
fnp-3528	130	59	weight	weight	NOUN
fnp-3528	130	60	in	in	ADP
fnp-3528	130	61	mice	mice	NOUN
fnp-3528	130	62	50	50	NUM
fnp-3528	130	63	µm	µm	ADP
fnp-3528	130	64	30–75	30–75	NUM
fnp-3528	130	65	mg	mg	PROPN
fnp-3528	130	66	/	/	SYM
fnp-3528	130	67	kg	kg	PROPN
fnp-3528	130	68	body	body	NOUN
fnp-3528	130	69	weight	weight	NOUN
fnp-3528	130	70	in	in	ADP
fnp-3528	130	71	mice	mouse	NOUN
fnp-3528	130	72	10	10	NUM
fnp-3528	130	73	µm	µm	ADP
fnp-3528	130	74	5–10	5–10	NOUN
fnp-3528	130	75	µm	µm	ADP
fnp-3528	130	76	;	;	PUNCT
fnp-3528	130	77	ec50	ec50	PROPN
fnp-3528	130	78	=	=	SYM
fnp-3528	130	79	1.28–7.474	1.28–7.474	NUM
fnp-3528	130	80	µm	µm	NOUN
fnp-3528	130	81	;	;	PUNCT
fnp-3528	130	82	20	20	NUM
fnp-3528	130	83	mg	mg	NUM
fnp-3528	130	84	/	/	SYM
fnp-3528	130	85	kg	kg	PROPN
fnp-3528	130	86	body	body	NOUN
fnp-3528	130	87	weight	weight	NOUN
fnp-3528	130	88	in	in	ADP
fnp-3528	130	89	mice	mouse	NOUN
fnp-3528	130	90	0.1–10	0.1–10	NOUN
fnp-3528	130	91	µm	µm	ADP
fnp-3528	130	92	5–20	5–20	PROPN
fnp-3528	130	93	µm	µm	ADP
fnp-3528	130	94	0.32	0.32	NUM
fnp-3528	130	95	µm	µm	ADP
fnp-3528	130	96	2–5	2–5	NUM
fnp-3528	130	97	µm	µm	ADP
fnp-3528	130	98	ec50	ec50	PROPN
fnp-3528	130	99	=	=	PUNCT
fnp-3528	130	100	2.91	2.91	NUM
fnp-3528	130	101	µm	µm	PART
fnp-3528	130	102	50	50	NUM
fnp-3528	130	103	µm	µm	ADP
fnp-3528	130	104	1–20	1–20	NOUN
fnp-3528	130	105	µm	µm	ADP
fnp-3528	130	106	1	1	NUM
fnp-3528	130	107	µm	µm	NUM
fnp-3528	130	108	;	;	PUNCT
fnp-3528	130	109	1	1	NUM
fnp-3528	130	110	mg	mg	PROPN
fnp-3528	130	111	/	/	SYM
fnp-3528	130	112	kg	kg	PROPN
fnp-3528	130	113	body	body	NOUN
fnp-3528	130	114	weight	weight	NOUN
fnp-3528	130	115	in	in	ADP
fnp-3528	130	116	mice	mouse	NOUN
fnp-3528	131	1	ec50	ec50	PROPN
fnp-3528	131	2	=	=	PUNCT
fnp-3528	131	3	0.85	0.85	NUM
fnp-3528	131	4	µm	µm	ADP
fnp-3528	131	5	20	20	NUM
fnp-3528	131	6	µm	µm	NUM
fnp-3528	131	7	;	;	PUNCT
fnp-3528	131	8	12.5	12.5	NUM
fnp-3528	131	9	mg	mg	PROPN
fnp-3528	131	10	/	/	SYM
fnp-3528	131	11	kg	kg	PROPN
fnp-3528	131	12	body	body	NOUN
fnp-3528	131	13	weight	weight	NOUN
fnp-3528	131	14	in	in	ADP
fnp-3528	131	15	mice	mouse	NOUN
fnp-3528	131	16	0.04–10	0.04–10	PROPN
fnp-3528	132	1	µm	µm	NOUN
fnp-3528	132	2	;	;	PUNCT
fnp-3528	132	3	ec50	ec50	PROPN
fnp-3528	132	4	=	=	PUNCT
fnp-3528	132	5	0.29	0.29	NUM
fnp-3528	132	6	µm	µm	ADP
fnp-3528	132	7	0.050	0.050	NUM
fnp-3528	132	8	µm	µm	ADP
fnp-3528	132	9	0.005	0.005	NUM
fnp-3528	132	10	µm	µm	ADP
fnp-3528	132	11	0.05–10	0.05–10	PROPN
fnp-3528	132	12	µm	µm	NOUN
fnp-3528	132	13	;	;	PUNCT
fnp-3528	132	14	ec50	ec50	PROPN
fnp-3528	132	15	=	=	PROPN
fnp-3528	132	16	1.49	1.49	NUM
fnp-3528	132	17	µm	µm	ADP
fnp-3528	132	18	5	5	NUM
fnp-3528	132	19	µm	µm	ADP
fnp-3528	132	20	0.035–34.98	0.035–34.98	NUM
fnp-3528	132	21	µm	µm	ADP
fnp-3528	132	22	;	;	PUNCT
fnp-3528	133	1	ec50	ec50	PROPN
fnp-3528	133	2	=	=	PUNCT
fnp-3528	133	3	0.27	0.27	NUM
fnp-3528	133	4	µm	µm	ADP
fnp-3528	133	5	2–8	2–8	NUM
fnp-3528	133	6	µm	µm	ADP
fnp-3528	133	7	10	10	NUM
fnp-3528	133	8	µm	µm	NUM
fnp-3528	133	9	20	20	NUM
fnp-3528	133	10	µm	µm	ADP
fnp-3528	133	11	50	50	NUM
fnp-3528	133	12	mg	mg	PROPN
fnp-3528	133	13	/	/	SYM
fnp-3528	133	14	kg	kg	NOUN
fnp-3528	133	15	body	body	NOUN
fnp-3528	133	16	weight	weight	NOUN
fnp-3528	133	17	in	in	ADP
fnp-3528	133	18	mice	mice	NOUN
fnp-3528	133	19	2.5–5	2.5–5	NUM
fnp-3528	133	20	µm	µm	ADP
fnp-3528	133	21	2–5	2–5	NUM
fnp-3528	133	22	µm	µm	ADP
fnp-3528	133	23	10	10	NUM
fnp-3528	133	24	µm	µm	ADP
fnp-3528	133	25	1	1	NUM
fnp-3528	133	26	µm	µm	ADP
fnp-3528	133	27	1	1	NUM
fnp-3528	133	28	µm	µm	ADP
fnp-3528	133	29	0.03–20	0.03–20	PROPN
fnp-3528	133	30	µm	µm	NOUN
fnp-3528	133	31	;	;	PUNCT
fnp-3528	133	32	ec50	ec50	PROPN
fnp-3528	133	33	=	=	PUNCT
fnp-3528	133	34	0.01391	0.01391	NUM
fnp-3528	133	35	µm	µm	ADP
fnp-3528	133	36	10	10	NUM
fnp-3528	133	37	µm	µm	PART
fnp-3528	133	38	2.5–3	2.5–3	NUM
fnp-3528	133	39	µm	µm	ADP
fnp-3528	133	40	u.d.b	u.d.b	NOUN
fnp-3528	133	41	in	in	ADP
fnp-3528	133	42	aphis	aphis	PROPN
fnp-3528	133	43	gossypii	gossypii	PROPN
fnp-3528	133	44	10	10	NUM
fnp-3528	133	45	µm	µm	ADP
fnp-3528	133	46	3–12	3–12	PROPN
fnp-3528	133	47	µm	µm	ADP
fnp-3528	133	48	0.001–0.01	0.001–0.01	ADJ
fnp-3528	133	49	µm	µm	ADP
fnp-3528	133	50	0.75	0.75	NUM
fnp-3528	133	51	%	%	NOUN
fnp-3528	133	52	of	of	ADP
fnp-3528	133	53	high	high	ADJ
fnp-3528	133	54	-	-	PUNCT
fnp-3528	133	55	fat	fat	NOUN
fnp-3528	133	56	diet	diet	NOUN
fnp-3528	133	57	in	in	ADP
fnp-3528	133	58	mice	mouse	NOUN
fnp-3528	133	59	0.1–25	0.1–25	X
fnp-3528	133	60	µm	µm	NOUN
fnp-3528	133	61	;	;	PUNCT
fnp-3528	133	62	ed50	ed50	PROPN
fnp-3528	133	63	=	=	PROPN
fnp-3528	133	64	4.11	4.11	NUM
fnp-3528	133	65	µmol	µmol	NOUN
fnp-3528	133	66	/	/	SYM
fnp-3528	133	67	kg	kg	NOUN
fnp-3528	133	68	body	body	NOUN
fnp-3528	133	69	weight	weight	NOUN
fnp-3528	133	70	in	in	ADP
fnp-3528	133	71	mice	mouse	NOUN
fnp-3528	133	72	10	10	NUM
fnp-3528	133	73	µm	µm	ADP
fnp-3528	133	74	99.2	99.2	NUM
fnp-3528	133	75	µm	µm	NUM
fnp-3528	133	76	;	;	PUNCT
fnp-3528	133	77	0.5	0.5	NUM
fnp-3528	133	78	mg	mg	PROPN
fnp-3528	133	79	/	/	SYM
fnp-3528	133	80	kg	kg	PROPN
fnp-3528	133	81	body	body	NOUN
fnp-3528	133	82	weight	weight	NOUN
fnp-3528	133	83	in	in	ADP
fnp-3528	133	84	mice	mouse	NOUN
fnp-3528	133	85	1	1	NUM
fnp-3528	133	86	µm	µm	ADP
fnp-3528	133	87	0.25–10	0.25–10	PROPN
fnp-3528	133	88	µm	µm	ADP
fnp-3528	133	89	20	20	NUM
fnp-3528	133	90	µm	µm	ADP
fnp-3528	133	91	0.1–10	0.1–10	NOUN
fnp-3528	133	92	µm	µm	ADP
fnp-3528	133	93	10	10	NUM
fnp-3528	133	94	µm	µm	ADP
fnp-3528	133	95	1	1	NUM
fnp-3528	133	96	µm	µm	ADP
fnp-3528	133	97	50	50	NUM
fnp-3528	133	98	µm	µm	ADP
fnp-3528	133	99	ed50	ed50	PROPN
fnp-3528	133	100	=	=	PUNCT
fnp-3528	133	101	in	in	ADP
fnp-3528	133	102	mice	mouse	NOUN
fnp-3528	133	103	0.05–100	0.05–100	ADV
fnp-3528	133	104	µm	µm	ADP
fnp-3528	133	105	1	1	NUM
fnp-3528	133	106	µm	µm	NUM
fnp-3528	133	107	;	;	PUNCT
fnp-3528	133	108	40	40	NUM
fnp-3528	133	109	mg	mg	NUM
fnp-3528	133	110	/	/	SYM
fnp-3528	133	111	kg	kg	PROPN
fnp-3528	133	112	body	body	NOUN
fnp-3528	133	113	weight	weight	NOUN
fnp-3528	133	114	in	in	ADP
fnp-3528	133	115	mice	mice	NOUN
fnp-3528	133	116	2.5–5	2.5–5	NUM
fnp-3528	133	117	µm	µm	ADP
fnp-3528	133	118	downregulators	downregulator	NOUN
fnp-3528	133	119	5cppss-50	5cppss-50	NUM
fnp-3528	133	120	acrolein	acrolein	ADJ
fnp-3528	133	121	8	8	NUM
fnp-3528	133	122	-	-	PUNCT
fnp-3528	133	123	br	br	NOUN
fnp-3528	133	124	-	-	PUNCT
fnp-3528	133	125	camp	camp	NOUN
fnp-3528	133	126	angiotensin	angiotensin	PROPN
fnp-3528	133	127	ii	ii	PROPN
fnp-3528	133	128	asymmetric	asymmetric	PROPN
fnp-3528	133	129	dimethylarginine	dimethylarginine	PROPN
fnp-3528	133	130	atorvastatin	atorvastatin	PROPN
fnp-3528	133	131	atr-101	atr-101	PROPN
fnp-3528	133	132	bisphenol	bisphenol	NOUN
fnp-3528	133	133	a	a	DET
fnp-3528	133	134	chalcone	chalcone	NOUN
fnp-3528	133	135	derivatives	derivative	VERB
fnp-3528	133	136	4-{[4-(4	4-{[4-(4	NUM
fnp-3528	133	137	-	-	PUNCT
fnp-3528	133	138	chlorophenyl)-2	chlorophenyl)-2	PROPN
fnp-3528	133	139	-	-	PUNCT
fnp-3528	133	140	thiazolyl]amino}phenol	thiazolyl]amino}phenol	PROPN
fnp-3528	133	141	cholesterol	cholesterol	NOUN
fnp-3528	133	142	dexamethasone	dexamethasone	NOUN
fnp-3528	133	143	dibutyl	dibutyl	NOUN
fnp-3528	133	144	phthalate	phthalate	NOUN
fnp-3528	133	145	egcg	egcg	NOUN
fnp-3528	133	146	fluvastatin	fluvastatin	PROPN
fnp-3528	133	147	ggpp	ggpp	PROPN
fnp-3528	133	148	gsk2033	gsk2033	PROPN
fnp-3528	133	149	gw6471	gw6471	PROPN
fnp-3528	133	150	gw9662	gw9662	PROPN
fnp-3528	133	151	desulfated	desulfate	VERB
fnp-3528	133	152	holothurin	holothurin	NOUN
fnp-3528	133	153	a	a	DET
fnp-3528	133	154	homocysteine	homocysteine	NOUN
fnp-3528	133	155	lipopolysaccharides	lipopolysaccharide	NOUN
fnp-3528	133	156	lovastatin	lovastatin	PROPN
fnp-3528	133	157	ly294002	ly294002	PROPN
fnp-3528	133	158	methionine	methionine	NOUN
fnp-3528	133	159	mevalonate	mevalonate	VERB
fnp-3528	133	160	mevastatin	mevastatin	NOUN
fnp-3528	133	161	mitotane	mitotane	ADJ
fnp-3528	133	162	ndea	ndea	NOUN
fnp-3528	133	163	1,2,3,4,6	1,2,3,4,6	NUM
fnp-3528	133	164	-	-	PUNCT
fnp-3528	133	165	penta	penta	ADJ
fnp-3528	133	166	-	-	PUNCT
fnp-3528	133	167	o	o	NOUN
fnp-3528	133	168	-	-	ADJ
fnp-3528	133	169	galloyl	galloyl	ADJ
fnp-3528	133	170	-	-	PUNCT
fnp-3528	133	171	β	β	NOUN
fnp-3528	133	172	-	-	ADJ
fnp-3528	133	173	d	d	NOUN
fnp-3528	133	174	-	-	PUNCT
fnp-3528	133	175	glucose	glucose	NOUN
fnp-3528	133	176	phenylalanine	phenylalanine	NOUN
fnp-3528	133	177	-	-	PUNCT
fnp-3528	133	178	proline	proline	NOUN
fnp-3528	133	179	pitavastatin	pitavastatin	NOUN
fnp-3528	133	180	pravastatin	pravastatin	NOUN
fnp-3528	133	181	raloxifene	raloxifene	NOUN
fnp-3528	133	182	rosuvastatin	rosuvastatin	PROPN
fnp-3528	133	183	simvastatin	simvastatin	PROPN
fnp-3528	133	184	sr9243	sr9243	PROPN
fnp-3528	133	185	tamoxifene	tamoxifene	VERB
fnp-3528	133	186	α	α	NOUN
fnp-3528	133	187	-	-	NOUN
fnp-3528	133	188	tocopherol	tocopherol	ADJ
fnp-3528	133	189	γ	γ	NOUN
fnp-3528	133	190	-	-	ADJ
fnp-3528	133	191	tocopherol	tocopherol	ADJ
fnp-3528	133	192	toremifene	toremifene	NOUN
fnp-3528	133	193	troglitazone	troglitazone	NOUN
fnp-3528	133	194	valproic	valproic	ADJ
fnp-3528	133	195	acid	acid	NOUN
fnp-3528	133	196	varenicline	varenicline	NOUN
fnp-3528	133	197	20	20	NUM
fnp-3528	133	198	µm	µm	ADP
fnp-3528	133	199	5–20	5–20	PROPN
fnp-3528	133	200	µm	µm	ADP
fnp-3528	133	201	0.3	0.3	NUM
fnp-3528	133	202	µm	µm	ADP
fnp-3528	133	203	0.0001–0.100	0.0001–0.100	NUM
fnp-3528	133	204	µm	µm	ADP
fnp-3528	133	205	0.5–1	0.5–1	NOUN
fnp-3528	133	206	µm	µm	ADP
fnp-3528	133	207	0.1–100	0.1–100	NUM
fnp-3528	133	208	µm	µm	ADP
fnp-3528	133	209	10–30	10–30	NUM
fnp-3528	133	210	µm	µm	ADP
fnp-3528	133	211	100	100	NUM
fnp-3528	133	212	µm	µm	ADP
fnp-3528	133	213	10	10	NUM
fnp-3528	133	214	µm	µm	PART
fnp-3528	133	215	5	5	NUM
fnp-3528	133	216	µm	µm	ADP
fnp-3528	133	217	150	150	NUM
fnp-3528	133	218	µm	µm	NUM
fnp-3528	133	219	0.1–2.5	0.1–2.5	NOUN
fnp-3528	133	220	µm	µm	NOUN
fnp-3528	133	221	;	;	PUNCT
fnp-3528	133	222	8	8	NUM
fnp-3528	133	223	mg	mg	NUM
fnp-3528	133	224	/	/	SYM
fnp-3528	133	225	kg	kg	PROPN
fnp-3528	133	226	body	body	NOUN
fnp-3528	133	227	weight	weight	NOUN
fnp-3528	133	228	in	in	ADP
fnp-3528	133	229	rats	rat	NOUN
fnp-3528	133	230	0.1	0.1	NUM
fnp-3528	133	231	µm	µm	ADP
fnp-3528	133	232	100	100	NUM
fnp-3528	133	233	mg	mg	NUM
fnp-3528	133	234	/	/	SYM
fnp-3528	133	235	kg	kg	PROPN
fnp-3528	133	236	body	body	NOUN
fnp-3528	133	237	weight	weight	NOUN
fnp-3528	133	238	in	in	ADP
fnp-3528	133	239	mice	mice	NOUN
fnp-3528	133	240	0.1–100	0.1–100	NOUN
fnp-3528	133	241	µm	µm	ADP
fnp-3528	133	242	10	10	NUM
fnp-3528	133	243	µm–200	µm–200	X
fnp-3528	133	244	µm	µm	ADP
fnp-3528	133	245	0.05–5	0.05–5	NUM
fnp-3528	133	246	µm	µm	ADP
fnp-3528	133	247	10	10	NUM
fnp-3528	133	248	µm	µm	PART
fnp-3528	133	249	10	10	NUM
fnp-3528	133	250	µm	µm	ADP
fnp-3528	133	251	2.68–4.47	2.68–4.47	NUM
fnp-3528	133	252	µm	µm	ADP
fnp-3528	133	253	50–200	50–200	NUM
fnp-3528	133	254	µm	µm	ADP
fnp-3528	133	255	1	1	NUM
fnp-3528	133	256	mg	mg	NUM
fnp-3528	133	257	/	/	SYM
fnp-3528	133	258	ml	ml	NOUN
fnp-3528	133	259	0.1–100	0.1–100	NOUN
fnp-3528	133	260	µm	µm	ADP
fnp-3528	133	261	20	20	NUM
fnp-3528	133	262	µm	µm	ADP
fnp-3528	133	263	17	17	NUM
fnp-3528	133	264	g	g	NOUN
fnp-3528	133	265	/	/	SYM
fnp-3528	133	266	kg	kg	NOUN
fnp-3528	133	267	food	food	NOUN
fnp-3528	133	268	in	in	ADP
fnp-3528	133	269	mice	mice	NOUN
fnp-3528	133	270	100	100	NUM
fnp-3528	133	271	µm	µm	ADP
fnp-3528	133	272	0.05–50	0.05–50	NOUN
fnp-3528	133	273	µm	µm	ADP
fnp-3528	133	274	50	50	NUM
fnp-3528	133	275	µm	µm	ADP
fnp-3528	133	276	100	100	NUM
fnp-3528	133	277	mg	mg	NUM
fnp-3528	133	278	/	/	SYM
fnp-3528	133	279	kg	kg	PROPN
fnp-3528	133	280	body	body	NOUN
fnp-3528	133	281	weight	weight	NOUN
fnp-3528	133	282	in	in	ADP
fnp-3528	133	283	rats	rat	NOUN
fnp-3528	133	284	25–300	25–300	NUM
fnp-3528	133	285	mg	mg	NUM
fnp-3528	133	286	/	/	SYM
fnp-3528	133	287	kg	kg	NOUN
fnp-3528	133	288	body	body	NOUN
fnp-3528	133	289	weight	weight	NOUN
fnp-3528	133	290	in	in	ADP
fnp-3528	133	291	mice	mouse	NOUN
fnp-3528	133	292	1000	1000	NUM
fnp-3528	133	293	µm	µm	NOUN
fnp-3528	133	294	;	;	PUNCT
fnp-3528	133	295	600	600	NUM
fnp-3528	133	296	mg	mg	PROPN
fnp-3528	133	297	/	/	SYM
fnp-3528	133	298	kg	kg	NOUN
fnp-3528	133	299	body	body	NOUN
fnp-3528	133	300	weight	weight	NOUN
fnp-3528	133	301	in	in	ADP
fnp-3528	133	302	rats	rat	NOUN
fnp-3528	133	303	10	10	NUM
fnp-3528	133	304	µm	µm	PART
fnp-3528	133	305	50	50	NUM
fnp-3528	133	306	µm	µm	ADP
fnp-3528	133	307	10	10	NUM
fnp-3528	133	308	µm	µm	ADP
fnp-3528	133	309	5–50	5–50	NOUN
fnp-3528	133	310	µm	µm	ADP
fnp-3528	133	311	0.1–100	0.1–100	NUM
fnp-3528	133	312	µm	µm	ADP
fnp-3528	133	313	1	1	NUM
fnp-3528	133	314	µm	µm	ADP
fnp-3528	133	315	2.5–10	2.5–10	NUM
fnp-3528	133	316	µm	µm	ADP
fnp-3528	133	317	50–100	50–100	NUM
fnp-3528	133	318	µm	µm	ADP
fnp-3528	133	319	50–100	50–100	NUM
fnp-3528	133	320	µm	µm	ADP
fnp-3528	133	321	10	10	NUM
fnp-3528	133	322	µm	µm	PART
fnp-3528	133	323	10	10	NUM
fnp-3528	133	324	µm	µm	ADP
fnp-3528	133	325	1000	1000	NUM
fnp-3528	133	326	µm	µm	ADP
fnp-3528	133	327	10	10	NUM
fnp-3528	133	328	µm	µm	NUM
fnp-3528	133	329	;	;	PUNCT
fnp-3528	133	330	0.5	0.5	NUM
fnp-3528	133	331	mg	mg	PROPN
fnp-3528	133	332	/	/	SYM
fnp-3528	133	333	kg	kg	PROPN
fnp-3528	133	334	body	body	NOUN
fnp-3528	133	335	weight	weight	NOUN
fnp-3528	133	336	in	in	ADP
fnp-3528	133	337	mice	mouse	NOUN
fnp-3528	133	338	stabilizers	stabilizer	NOUN
fnp-3528	133	339	cyclosporine	cyclosporine	VERB
fnp-3528	133	340	a	a	DET
fnp-3528	133	341	diphenoquinone	diphenoquinone	NOUN
fnp-3528	133	342	erythrodiol	erythrodiol	ADJ
fnp-3528	133	343	alln	alln	PROPN
fnp-3528	133	344	leupeptin	leupeptin	PROPN
fnp-3528	133	345	probucol	probucol	PROPN
fnp-3528	133	346	spiroquinone	spiroquinone	NOUN
fnp-3528	133	347	testosterone	testosterone	NOUN
fnp-3528	133	348	wogonin	wogonin	NOUN
fnp-3528	133	349	10	10	NUM
fnp-3528	133	350	µm	µm	PART
fnp-3528	133	351	0.0001–0.0005	0.0001–0.0005	PROPN
fnp-3528	133	352	µm	µm	ADP
fnp-3528	133	353	10–15	10–15	NUM
fnp-3528	133	354	µm	µm	ADP
fnp-3528	133	355	50	50	NUM
fnp-3528	133	356	µm	µm	ADP
fnp-3528	133	357	1170	1170	NUM
fnp-3528	133	358	µm	µm	ADP
fnp-3528	133	359	u.c.a	u.c.a	NOUN
fnp-3528	133	360	0.025–0.050	0.025–0.050	NUM
fnp-3528	133	361	µm	µm	ADP
fnp-3528	133	362	0.01	0.01	NUM
fnp-3528	133	363	µm	µm	ADP
fnp-3528	133	364	10–40	10–40	NUM
fnp-3528	133	365	µm	µm	ADP
fnp-3528	133	366	destabilizers	destabilizer	NOUN
fnp-3528	133	367	brefeldin	brefeldin	VERB
fnp-3528	133	368	a	a	DET
fnp-3528	133	369	2	2	NUM
fnp-3528	133	370	-	-	PUNCT
fnp-3528	133	371	bromopalmitate	bromopalmitate	NOUN
fnp-3528	133	372	cycloheximide	cycloheximide	NOUN
fnp-3528	133	373	gö6976	gö6976	NOUN
fnp-3528	133	374	monensin	monensin	VERB
fnp-3528	133	375	a	a	DET
fnp-3528	133	376	serdemetan	serdemetan	ADJ
fnp-3528	133	377	tunicamycin	tunicamycin	NOUN
fnp-3528	133	378	17.8–36	17.8–36	NUM
fnp-3528	133	379	µm	µm	ADP
fnp-3528	133	380	7.5–60	7.5–60	NUM
fnp-3528	133	381	µm	µm	NOUN
fnp-3528	133	382	;	;	PUNCT
fnp-3528	133	383	ic50	ic50	PROPN
fnp-3528	133	384	=	=	PROPN
fnp-3528	133	385	15	15	NUM
fnp-3528	133	386	µm	µm	ADP
fnp-3528	133	387	355	355	NUM
fnp-3528	133	388	µm	µm	ADP
fnp-3528	133	389	10	10	NUM
fnp-3528	133	390	µm	µm	PART
fnp-3528	133	391	10	10	NUM
fnp-3528	133	392	µm	µm	ADP
fnp-3528	133	393	2–5	2–5	NUM
fnp-3528	133	394	µm	µm	ADP
fnp-3528	133	395	2.41	2.41	NUM
fnp-3528	133	396	µm	µm	ADP
fnp-3528	133	397	a	a	DET
fnp-3528	133	398	u.c	u.c	PROPN
fnp-3528	133	399	.	.	PUNCT
fnp-3528	133	400	=	=	PUNCT
fnp-3528	134	1	unspecified	unspecified	ADJ
fnp-3528	134	2	concentration	concentration	NOUN
fnp-3528	134	3	b	b	X
fnp-3528	134	4	u.d	u.d	PROPN
fnp-3528	134	5	.	.	PUNCT
fnp-3528	135	1	=	=	SYM
fnp-3528	135	2	unspecified	unspecified	ADJ
fnp-3528	135	3	dose	dose	NOUN
fnp-3528	135	4	strikingly	strikingly	ADV
fnp-3528	135	5	,	,	PUNCT
fnp-3528	135	6	abca2	abca2	PRON
fnp-3528	135	7	co	co	VERB
fnp-3528	135	8	-	-	VERB
fnp-3528	135	9	localized	localize	VERB
fnp-3528	135	10	with	with	ADP
fnp-3528	135	11	the	the	DET
fnp-3528	135	12	lysosomal	lysosomal	NOUN
fnp-3528	135	13	-	-	PUNCT
fnp-3528	135	14	associated	associate	VERB
fnp-3528	135	15	membrane	membrane	NOUN
fnp-3528	135	16	protein	protein	NOUN
fnp-3528	135	17	1	1	NUM
fnp-3528	135	18	(	(	PUNCT
fnp-3528	135	19	lamp1	lamp1	NOUN
fnp-3528	135	20	)	)	PUNCT
fnp-3528	135	21	–	–	PUNCT
fnp-3528	135	22	an	an	DET
fnp-3528	135	23	endolysosomal	endolysosomal	ADJ
fnp-3528	135	24	marker	marker	NOUN
fnp-3528	135	25	–	–	PUNCT
fnp-3528	135	26	as	as	ADV
fnp-3528	135	27	well	well	ADV
fnp-3528	135	28	as	as	ADP
fnp-3528	135	29	the	the	DET
fnp-3528	135	30	fluorescence	fluorescence	NOUN
fnp-3528	135	31	probe	probe	VERB
fnp-3528	135	32	dansyl	dansyl	NOUN
fnp-3528	135	33	-	-	PUNCT
fnp-3528	135	34	estramustine	estramustine	NOUN
fnp-3528	135	35	.	.	PUNCT
fnp-3528	136	1	this	this	DET
fnp-3528	136	2	co	co	NOUN
fnp-3528	136	3	-	-	NOUN
fnp-3528	136	4	localization	localization	NOUN
fnp-3528	136	5	indicates	indicate	VERB
fnp-3528	136	6	a	a	DET
fnp-3528	136	7	direct	direct	ADJ
fnp-3528	136	8	sequestration	sequestration	NOUN
fnp-3528	136	9	of	of	ADP
fnp-3528	136	10	this	this	DET
fnp-3528	136	11	antineoplastic	antineoplastic	ADJ
fnp-3528	136	12	drug	drug	NOUN
fnp-3528	136	13	into	into	ADP
fnp-3528	136	14	endoand	endoand	PROPN
fnp-3528	136	15	/	/	SYM
fnp-3528	136	16	or	or	CCONJ
fnp-3528	136	17	lysosomes.171	lysosomes.171	NOUN
fnp-3528	136	18	on	on	ADP
fnp-3528	136	19	the	the	DET
fnp-3528	136	20	other	other	ADJ
fnp-3528	136	21	hand	hand	NOUN
fnp-3528	136	22	,	,	PUNCT
fnp-3528	136	23	the	the	DET
fnp-3528	136	24	susceptibility	susceptibility	NOUN
fnp-3528	136	25	of	of	ADP
fnp-3528	136	26	abca3	abca3	NOUN
fnp-3528	136	27	-	-	PUNCT
fnp-3528	136	28	overexpressing	overexpresse	VERB
fnp-3528	136	29	ccrf	ccrf	NOUN
fnp-3528	136	30	-	-	PUNCT
fnp-3528	136	31	cem	cem	NOUN
fnp-3528	136	32	leukemia	leukemia	NOUN
fnp-3528	136	33	cells	cell	NOUN
fnp-3528	136	34	to	to	ADP
fnp-3528	136	35	the	the	DET
fnp-3528	136	36	antineoplastic	antineoplastic	ADJ
fnp-3528	136	37	agents	agent	NOUN
fnp-3528	136	38	cytarabine	cytarabine	NOUN
fnp-3528	136	39	,	,	PUNCT
fnp-3528	136	40	methotrexate	methotrexate	NOUN
fnp-3528	136	41	(	(	PUNCT
fnp-3528	136	42	figure	figure	NOUN
fnp-3528	136	43	 	 	SPACE
fnp-3528	136	44	1	1	NUM
fnp-3528	136	45	)	)	PUNCT
fnp-3528	136	46	,	,	PUNCT
fnp-3528	136	47	vincristine	vincristine	NOUN
fnp-3528	136	48	,	,	PUNCT
fnp-3528	136	49	but	but	CCONJ
fnp-3528	136	50	also	also	ADV
fnp-3528	136	51	the	the	DET
fnp-3528	136	52	anti	anti	ADJ
fnp-3528	136	53	-	-	ADJ
fnp-3528	136	54	inflammatory	inflammatory	ADJ
fnp-3528	136	55	drug	drug	NOUN
fnp-3528	136	56	dexamethasone	dexamethasone	NOUN
fnp-3528	136	57	,	,	PUNCT
fnp-3528	136	58	was	be	AUX
fnp-3528	136	59	reduced	reduce	VERB
fnp-3528	136	60	compared	compare	VERB
fnp-3528	136	61	to	to	ADP
fnp-3528	136	62	their	their	PRON
fnp-3528	136	63	parental	parental	ADJ
fnp-3528	136	64	counterparts.242	counterparts.242	NOUN
fnp-3528	136	65	taken	take	VERB
fnp-3528	136	66	together	together	ADV
fnp-3528	136	67	,	,	PUNCT
fnp-3528	136	68	abca2	abca2	NOUN
fnp-3528	136	69	and	and	CCONJ
fnp-3528	136	70	abca3	abca3	PROPN
fnp-3528	136	71	are	be	AUX
fnp-3528	136	72	contributors	contributor	NOUN
fnp-3528	136	73	to	to	ADP
fnp-3528	136	74	mdr	mdr	PROPN
fnp-3528	136	75	,	,	PUNCT
fnp-3528	136	76	and	and	CCONJ
fnp-3528	136	77	the	the	DET
fnp-3528	136	78	number	number	NOUN
fnp-3528	136	79	of	of	ADP
fnp-3528	136	80	potential	potential	ADJ
fnp-3528	136	81	abca2	abca2	NOUN
fnp-3528	136	82	and	and	CCONJ
fnp-3528	136	83	abca3	abca3	PROPN
fnp-3528	136	84	substrates	substrate	NOUN
fnp-3528	136	85	may	may	AUX
fnp-3528	136	86	be	be	AUX
fnp-3528	136	87	even	even	ADV
fnp-3528	136	88	higher	high	ADJ
fnp-3528	136	89	than	than	SCONJ
fnp-3528	136	90	currently	currently	ADV
fnp-3528	136	91	suggested	suggest	VERB
fnp-3528	136	92	.	.	PUNCT
fnp-3528	137	1	interestingly	interestingly	ADV
fnp-3528	137	2	,	,	PUNCT
fnp-3528	137	3	missense	missense	VERB
fnp-3528	137	4	mutations	mutation	NOUN
fnp-3528	137	5	of	of	ADP
fnp-3528	137	6	abca4	abca4	PROPN
fnp-3528	137	7	were	be	AUX
fnp-3528	137	8	associated	associate	VERB
fnp-3528	137	9	with	with	ADP
fnp-3528	137	10	chloroquineand	chloroquineand	NOUN
fnp-3528	137	11	hydroxychloroquine	hydroxychloroquine	PROPN
fnp-3528	137	12	-	-	PUNCT
fnp-3528	137	13	associated	associate	VERB
fnp-3528	137	14	retinopathy,243	retinopathy,243	NOUN
fnp-3528	137	15	although	although	SCONJ
fnp-3528	137	16	contradictory	contradictory	ADJ
fnp-3528	137	17	studies	study	NOUN
fnp-3528	137	18	exist.244	exist.244	VERB
fnp-3528	137	19	a	a	DET
fnp-3528	137	20	direct	direct	ADJ
fnp-3528	137	21	interaction	interaction	NOUN
fnp-3528	137	22	was	be	AUX
fnp-3528	137	23	postulated	postulate	VERB
fnp-3528	137	24	,	,	PUNCT
fnp-3528	137	25	however	however	ADV
fnp-3528	137	26	,	,	PUNCT
fnp-3528	137	27	not	not	PART
fnp-3528	137	28	proven	prove	VERB
fnp-3528	137	29	.	.	PUNCT
fnp-3528	138	1	nevertheless	nevertheless	ADV
fnp-3528	138	2	,	,	PUNCT
fnp-3528	138	3	these	these	DET
fnp-3528	138	4	results	result	NOUN
fnp-3528	138	5	suggest	suggest	VERB
fnp-3528	138	6	chloroquine	chloroquine	NOUN
fnp-3528	138	7	and	and	CCONJ
fnp-3528	138	8	hydroxychloroquine	hydroxychloroquine	NOUN
fnp-3528	138	9	as	as	ADP
fnp-3528	138	10	potential	potential	ADJ
fnp-3528	138	11	abca4	abca4	ADJ
fnp-3528	138	12	substrates	substrate	NOUN
fnp-3528	138	13	.	.	PUNCT
fnp-3528	139	1	table	table	NOUN
fnp-3528	139	2	3	3	NUM
fnp-3528	139	3	.	.	PUNCT
fnp-3528	139	4	currently	currently	ADV
fnp-3528	139	5	known	know	VERB
fnp-3528	139	6	modulators	modulator	NOUN
fnp-3528	139	7	of	of	ADP
fnp-3528	139	8	abca	abca	NOUN
fnp-3528	139	9	transporters	transporter	NOUN
fnp-3528	139	10	other	other	ADJ
fnp-3528	139	11	than	than	ADP
fnp-3528	139	12	abca1	abca1	NOUN
fnp-3528	139	13	.	.	PUNCT
fnp-3528	140	1	mode	mode	NOUN
fnp-3528	140	2	of	of	ADP
fnp-3528	140	3	modulation	modulation	NOUN
fnp-3528	140	4	name	name	NOUN
fnp-3528	140	5	of	of	ADP
fnp-3528	140	6	modulator	modulator	NOUN
fnp-3528	140	7	effect	effect	NOUN
fnp-3528	140	8	concentration	concentration	NOUN
fnp-3528	140	9	;	;	PUNCT
fnp-3528	140	10	concentration	concentration	NOUN
fnp-3528	140	11	range	range	NOUN
fnp-3528	140	12	;	;	PUNCT
fnp-3528	141	1	ec50	ec50	PROPN
fnp-3528	141	2	;	;	PUNCT
fnp-3528	141	3	dose	dose	VERB
fnp-3528	141	4	;	;	PUNCT
fnp-3528	141	5	ed50	ed50	PROPN
fnp-3528	141	6	abca2	abca2	NOUN
fnp-3528	141	7	(	(	PUNCT
fnp-3528	141	8	potential	potential	ADJ
fnp-3528	141	9	)	)	PUNCT
fnp-3528	141	10	substrates	substrate	NOUN
fnp-3528	141	11	cytarabine	cytarabine	NOUN
fnp-3528	141	12	dexamethasone	dexamethasone	PROPN
fnp-3528	141	13	estramustine	estramustine	PROPN
fnp-3528	141	14	estradiol	estradiol	PROPN
fnp-3528	141	15	estrone	estrone	PROPN
fnp-3528	141	16	imatinib	imatinib	NOUN
fnp-3528	141	17	methotrexate	methotrexate	VERB
fnp-3528	141	18	inducers	inducer	NOUN
fnp-3528	141	19	imatinib	imatinib	NOUN
fnp-3528	141	20	methotrexate	methotrexate	VERB
fnp-3528	141	21	progesterone	progesterone	NOUN
fnp-3528	141	22	sulfoxaflor	sulfoxaflor	NOUN
fnp-3528	141	23	u18666a	u18666a	NOUN
fnp-3528	141	24	u.c.b	u.c.b	NOUN
fnp-3528	141	25	1.28	1.28	NUM
fnp-3528	141	26	µm	µm	ADP
fnp-3528	141	27	31.8	31.8	NUM
fnp-3528	141	28	µm	µm	ADP
fnp-3528	141	29	u.d.c	u.d.c	PROPN
fnp-3528	141	30	in	in	ADP
fnp-3528	141	31	aphis	aphis	PROPN
fnp-3528	141	32	gossypii	gossypii	PROPN
fnp-3528	141	33	5	5	NUM
fnp-3528	141	34	µm	µm	ADP
fnp-3528	141	35	downregulators	downregulator	NOUN
fnp-3528	141	36	celecoxib	celecoxib	VERB
fnp-3528	141	37	10	10	NUM
fnp-3528	141	38	µm	µm	NOUN
fnp-3528	141	39	abca3	abca3	PROPN
fnp-3528	142	1	(	(	PUNCT
fnp-3528	142	2	potential	potential	ADJ
fnp-3528	142	3	)	)	PUNCT
fnp-3528	142	4	substrates	substrate	VERB
fnp-3528	142	5	cisplatin	cisplatin	NOUN
fnp-3528	142	6	cytarabine	cytarabine	PROPN
fnp-3528	142	7	dasatinib	dasatinib	NOUN
fnp-3528	142	8	daunorubicin	daunorubicin	PROPN
fnp-3528	142	9	dexamethasone	dexamethasone	NOUN
fnp-3528	142	10	doxorubicin	doxorubicin	PROPN
fnp-3528	142	11	etoposide	etoposide	PROPN
fnp-3528	142	12	imatinib	imatinib	NOUN
fnp-3528	142	13	methotrexate	methotrexate	VERB
fnp-3528	142	14	miltefosine	miltefosine	ADJ
fnp-3528	142	15	mitoxantrone	mitoxantrone	NOUN
fnp-3528	142	16	nilotinib	nilotinib	NOUN
fnp-3528	142	17	paclitaxel	paclitaxel	PROPN
fnp-3528	142	18	vincristine	vincristine	NOUN
fnp-3528	142	19	inducers	inducer	NOUN
fnp-3528	142	20	dasatinib	dasatinib	VERB
fnp-3528	142	21	5	5	NUM
fnp-3528	142	22	-	-	PUNCT
fnp-3528	142	23	fu	fu	NOUN
fnp-3528	142	24	imatinib	imatinib	NOUN
fnp-3528	142	25	methotrexate	methotrexate	VERB
fnp-3528	142	26	nilotinib	nilotinib	NOUN
fnp-3528	142	27	vitamin	vitamin	NOUN
fnp-3528	142	28	c	c	NOUN
fnp-3528	142	29	u.c.b	u.c.b	NOUN
fnp-3528	142	30	50	50	NUM
fnp-3528	142	31	µm	µm	NOUN
fnp-3528	142	32	0.1–12.5	0.1–12.5	NUM
fnp-3528	142	33	µm	µm	ADP
fnp-3528	142	34	1.28	1.28	NUM
fnp-3528	142	35	µm	µm	ADP
fnp-3528	142	36	u.c.b	u.c.b	NOUN
fnp-3528	142	37	56.78	56.78	NUM
fnp-3528	142	38	µm	µm	ADP
fnp-3528	142	39	downregulators	downregulator	NOUN
fnp-3528	142	40	genistein	genistein	PROPN
fnp-3528	142	41	indomethacin	indomethacin	VERB
fnp-3528	142	42	lipopolysaccharides	lipopolysaccharide	NOUN
fnp-3528	142	43	pk11195	pk11195	PROPN
fnp-3528	142	44	sirolimus	sirolimus	VERB
fnp-3528	142	45	3–9	3–9	NUM
fnp-3528	142	46	µm	µm	ADP
fnp-3528	142	47	2	2	NUM
fnp-3528	142	48	µm	µm	ADP
fnp-3528	142	49	10	10	NUM
fnp-3528	142	50	µg	µg	ADV
fnp-3528	142	51	/	/	SYM
fnp-3528	142	52	ml	ml	NOUN
fnp-3528	142	53	;	;	PUNCT
fnp-3528	142	54	100	100	NUM
fnp-3528	142	55	µg	µg	NOUN
fnp-3528	142	56	/	/	SYM
fnp-3528	142	57	ml	ml	NOUN
fnp-3528	142	58	in	in	ADP
fnp-3528	142	59	chicken	chicken	NOUN
fnp-3528	142	60	lungs	lung	NOUN
fnp-3528	142	61	u.c.b	u.c.b	NOUN
fnp-3528	142	62	2	2	NUM
fnp-3528	142	63	µm	µm	ADP
fnp-3528	142	64	stabilizers	stabilizer	NOUN
fnp-3528	142	65	c13	c13	PROPN
fnp-3528	142	66	c14	c14	PROPN
fnp-3528	142	67	c17	c17	PROPN
fnp-3528	142	68	genistein	genistein	PROPN
fnp-3528	142	69	ivacaftor	ivacaftor	VERB
fnp-3528	142	70	10	10	NUM
fnp-3528	142	71	µm	µm	PART
fnp-3528	142	72	10	10	NUM
fnp-3528	142	73	µm	µm	PART
fnp-3528	142	74	10	10	NUM
fnp-3528	142	75	µm	µm	PART
fnp-3528	142	76	10	10	NUM
fnp-3528	142	77	µm	µm	ADP
fnp-3528	142	78	1	1	NUM
fnp-3528	142	79	µm	µm	ADP
fnp-3528	142	80	abca4	abca4	PROPN
fnp-3528	142	81	(	(	PUNCT
fnp-3528	142	82	potential	potential	ADJ
fnp-3528	142	83	)	)	PUNCT
fnp-3528	142	84	substrates	substrate	VERB
fnp-3528	142	85	chloroquine	chloroquine	NOUN
fnp-3528	142	86	hydroxychloroquine	hydroxychloroquine	PROPN
fnp-3528	142	87	β	β	NOUN
fnp-3528	142	88	-	-	PUNCT
fnp-3528	142	89	ionone	ionone	ADJ
fnp-3528	142	90	11	11	NUM
fnp-3528	142	91	-	-	PUNCT
fnp-3528	142	92	cis	cis	NOUN
fnp-3528	142	93	-	-	PUNCT
fnp-3528	142	94	retinal	retinal	ADJ
fnp-3528	142	95	13	13	NUM
fnp-3528	142	96	-	-	PUNCT
fnp-3528	142	97	cis	cis	NOUN
fnp-3528	142	98	-	-	PUNCT
fnp-3528	142	99	retinal	retinal	ADJ
fnp-3528	142	100	all	all	DET
fnp-3528	142	101	-	-	PUNCT
fnp-3528	142	102	trans	trans	NOUN
fnp-3528	142	103	-	-	ADJ
fnp-3528	142	104	retinal	retinal	ADJ
fnp-3528	142	105	all	all	DET
fnp-3528	142	106	-	-	PUNCT
fnp-3528	142	107	trans	trans	ADJ
fnp-3528	142	108	-	-	ADJ
fnp-3528	142	109	retinoic	retinoic	ADJ
fnp-3528	142	110	acid	acid	NOUN
fnp-3528	142	111	all	all	PROPN
fnp-3528	142	112	-	-	PUNCT
fnp-3528	142	113	trans	trans	ADJ
fnp-3528	142	114	-	-	ADJ
fnp-3528	142	115	retinol	retinol	ADJ
fnp-3528	142	116	n	n	CCONJ
fnp-3528	142	117	-	-	PUNCT
fnp-3528	142	118	retinylidene	retinylidene	NOUN
fnp-3528	142	119	-	-	PUNCT
fnp-3528	142	120	phosphatidyl	phosphatidyl	NOUN
fnp-3528	142	121	-	-	PUNCT
fnp-3528	142	122	ethanolamine	ethanolamine	NOUN
fnp-3528	142	123	phosphatidyl	phosphatidyl	NOUN
fnp-3528	142	124	-	-	PUNCT
fnp-3528	142	125	ethanolamine	ethanolamine	NOUN
fnp-3528	142	126	stabilizers	stabilizer	NOUN
fnp-3528	142	127	c3	c3	PROPN
fnp-3528	142	128	c4	c4	PROPN
fnp-3528	142	129	c18	c18	PROPN
fnp-3528	142	130	lumacaftor	lumacaftor	PROPN
fnp-3528	142	131	10–20	10–20	NUM
fnp-3528	142	132	µm	µm	ADP
fnp-3528	142	133	1–20	1–20	NOUN
fnp-3528	142	134	µm	µm	ADP
fnp-3528	142	135	10–20	10–20	NUM
fnp-3528	142	136	µm	µm	ADP
fnp-3528	142	137	10–20	10–20	NUM
fnp-3528	142	138	µm	µm	ADP
fnp-3528	142	139	abca5	abca5	NOUN
fnp-3528	142	140	inducers	inducer	NOUN
fnp-3528	142	141	atorvastatin	atorvastatin	PROPN
fnp-3528	142	142	bezafibrate	bezafibrate	PROPN
fnp-3528	142	143	cholesterol	cholesterol	NOUN
fnp-3528	142	144	gw3965	gw3965	PROPN
fnp-3528	142	145	rosiglitazone	rosiglitazone	NOUN
fnp-3528	142	146	tacrolimus	tacrolimus	NOUN
fnp-3528	142	147	troglitazone	troglitazone	NOUN
fnp-3528	142	148	20	20	NUM
fnp-3528	142	149	µm	µm	PART
fnp-3528	142	150	10	10	NUM
fnp-3528	142	151	µm	µm	ADP
fnp-3528	142	152	100–150	100–150	NUM
fnp-3528	142	153	µm	µm	ADP
fnp-3528	142	154	0.5	0.5	NUM
fnp-3528	142	155	µm	µm	ADP
fnp-3528	142	156	10	10	NUM
fnp-3528	142	157	µm	µm	ADP
fnp-3528	142	158	0.04	0.04	NUM
fnp-3528	142	159	µm	µm	ADP
fnp-3528	142	160	10	10	NUM
fnp-3528	142	161	µm	µm	ADP
fnp-3528	142	162	downregulators	downregulator	NOUN
fnp-3528	142	163	digoxin	digoxin	VERB
fnp-3528	142	164	2.5	2.5	NUM
fnp-3528	142	165	g	g	NOUN
fnp-3528	142	166	/	/	SYM
fnp-3528	142	167	kg	kg	NOUN
fnp-3528	142	168	body	body	NOUN
fnp-3528	142	169	weight	weight	NOUN
fnp-3528	142	170	in	in	ADP
fnp-3528	142	171	mice	mouse	NOUN
fnp-3528	142	172	abca6	abca6	PROPN
fnp-3528	142	173	inducers	inducer	NOUN
fnp-3528	142	174	acitretin	acitretin	VERB
fnp-3528	142	175	lovastatin	lovastatin	PROPN
fnp-3528	142	176	mevastatin	mevastatin	PROPN
fnp-3528	142	177	1–10	1–10	PROPN
fnp-3528	142	178	mg	mg	PROPN
fnp-3528	142	179	/	/	SYM
fnp-3528	142	180	kg	kg	PROPN
fnp-3528	142	181	body	body	NOUN
fnp-3528	142	182	weight	weight	NOUN
fnp-3528	142	183	in	in	ADP
fnp-3528	142	184	pigs	pig	NOUN
fnp-3528	142	185	10	10	NUM
fnp-3528	142	186	µm	µm	PART
fnp-3528	142	187	10	10	NUM
fnp-3528	142	188	µm	µm	ADP
fnp-3528	142	189	downregulators	downregulator	NOUN
fnp-3528	142	190	lovastatin	lovastatin	PROPN
fnp-3528	142	191	mevastatin	mevastatin	PROPN
fnp-3528	142	192	10	10	NUM
fnp-3528	142	193	µm	µm	PART
fnp-3528	142	194	10	10	NUM
fnp-3528	142	195	µm	µm	ADP
fnp-3528	142	196	abca7	abca7	NOUN
fnp-3528	142	197	inducers	inducer	NOUN
fnp-3528	142	198	ponasterone	ponasterone	VERB
fnp-3528	142	199	a	a	DET
fnp-3528	142	200	pravastatin	pravastatin	PROPN
fnp-3528	142	201	rosuvastatin	rosuvastatin	NOUN
fnp-3528	142	202	1–5	1–5	PROPN
fnp-3528	142	203	µm	µm	ADP
fnp-3528	142	204	50	50	NUM
fnp-3528	142	205	µm	µm	ADP
fnp-3528	142	206	5	5	NUM
fnp-3528	142	207	µm	µm	ADP
fnp-3528	142	208	downregulators	downregulator	NOUN
fnp-3528	142	209	cholesterol	cholesterol	NOUN
fnp-3528	142	210	digoxin	digoxin	PROPN
fnp-3528	142	211	25	25	NUM
fnp-3528	142	212	-	-	PUNCT
fnp-3528	142	213	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	142	214	2	2	NUM
fnp-3528	142	215	mm	mm	NOUN
fnp-3528	142	216	2.5	2.5	NUM
fnp-3528	142	217	g	g	NOUN
fnp-3528	142	218	/	/	SYM
fnp-3528	142	219	kg	kg	NOUN
fnp-3528	142	220	body	body	NOUN
fnp-3528	142	221	weight	weight	NOUN
fnp-3528	142	222	in	in	ADP
fnp-3528	142	223	mice	mice	NOUN
fnp-3528	142	224	2.48	2.48	NUM
fnp-3528	142	225	µm	µm	ADP
fnp-3528	142	226	abca8	abca8	PROPN
fnp-3528	143	1	(	(	PUNCT
fnp-3528	143	2	potential	potential	ADJ
fnp-3528	143	3	)	)	PUNCT
fnp-3528	143	4	substrates	substrate	VERB
fnp-3528	143	5	p	p	ADJ
fnp-3528	143	6	-	-	PUNCT
fnp-3528	143	7	aminohippuric	aminohippuric	ADJ
fnp-3528	143	8	acid	acid	PROPN
fnp-3528	143	9	estradiol	estradiol	PROPN
fnp-3528	143	10	-	-	PUNCT
fnp-3528	143	11	β	β	NOUN
fnp-3528	143	12	-	-	ADJ
fnp-3528	143	13	glucuronide	glucuronide	ADJ
fnp-3528	143	14	estrone	estrone	NOUN
fnp-3528	143	15	sulfate	sulfate	NOUN
fnp-3528	143	16	glibenclamide	glibenclamide	NOUN
fnp-3528	143	17	leukotriene	leukotriene	NOUN
fnp-3528	143	18	c4	c4	PROPN
fnp-3528	143	19	ochratoxin	ochratoxin	VERB
fnp-3528	143	20	a	a	DET
fnp-3528	143	21	taurocholic	taurocholic	ADJ
fnp-3528	143	22	acid	acid	NOUN
fnp-3528	143	23	(	(	PUNCT
fnp-3528	143	24	potential	potential	ADJ
fnp-3528	143	25	)	)	PUNCT
fnp-3528	143	26	inhibitors	inhibitor	NOUN
fnp-3528	143	27	digoxin	digoxin	NOUN
fnp-3528	143	28	dofequidar	dofequidar	PROPN
fnp-3528	143	29	glibenclamide	glibenclamide	NOUN
fnp-3528	143	30	ochratoxin	ochratoxin	PROPN
fnp-3528	144	1	a	a	DET
fnp-3528	144	2	probenecid	probenecid	PROPN
fnp-3528	144	3	verapamil	verapamil	NOUN
fnp-3528	144	4	verlukast	verlukast	VERB
fnp-3528	144	5	250	250	NUM
fnp-3528	144	6	µm	µm	PART
fnp-3528	144	7	10	10	NUM
fnp-3528	144	8	µm	µm	ADP
fnp-3528	144	9	250	250	NUM
fnp-3528	144	10	µm	µm	ADP
fnp-3528	144	11	50	50	NUM
fnp-3528	144	12	µm	µm	ADP
fnp-3528	144	13	1000	1000	NUM
fnp-3528	144	14	µm	µm	ADP
fnp-3528	144	15	1000	1000	NUM
fnp-3528	144	16	µm	µm	ADP
fnp-3528	144	17	100	100	NUM
fnp-3528	144	18	µm	µm	ADP
fnp-3528	144	19	inducers	inducer	NOUN
fnp-3528	144	20	gemcitabine	gemcitabine	VERB
fnp-3528	144	21	polyethyleneglycol	polyethyleneglycol	NOUN
fnp-3528	144	22	-	-	PUNCT
fnp-3528	144	23	block	block	NOUN
fnp-3528	144	24	-	-	PUNCT
fnp-3528	144	25	polyactide	polyactide	NOUN
fnp-3528	144	26	nanoparticles	nanoparticle	NOUN
fnp-3528	144	27	0.05–0.8	0.05–0.8	NUM
fnp-3528	144	28	µm	µm	ADP
fnp-3528	144	29	42.04	42.04	NUM
fnp-3528	144	30	g	g	NOUN
fnp-3528	144	31	/	/	SYM
fnp-3528	144	32	kg	kg	NOUN
fnp-3528	144	33	body	body	NOUN
fnp-3528	144	34	weight	weight	NOUN
fnp-3528	144	35	in	in	ADP
fnp-3528	144	36	rats	rat	NOUN
fnp-3528	144	37	downregulators	downregulator	NOUN
fnp-3528	144	38	digoxin	digoxin	VERB
fnp-3528	144	39	2.5	2.5	NUM
fnp-3528	144	40	g	g	NOUN
fnp-3528	144	41	/	/	SYM
fnp-3528	144	42	kg	kg	NOUN
fnp-3528	144	43	body	body	NOUN
fnp-3528	144	44	weight	weight	NOUN
fnp-3528	144	45	in	in	ADP
fnp-3528	144	46	mice	mouse	NOUN
fnp-3528	144	47	abca9	abca9	PROPN
fnp-3528	144	48	downregulators	downregulator	NOUN
fnp-3528	144	49	digoxin	digoxin	VERB
fnp-3528	144	50	2.5	2.5	NUM
fnp-3528	144	51	g	g	NOUN
fnp-3528	144	52	/	/	SYM
fnp-3528	144	53	kg	kg	NOUN
fnp-3528	144	54	body	body	NOUN
fnp-3528	144	55	weight	weight	NOUN
fnp-3528	144	56	in	in	ADP
fnp-3528	144	57	mice	mouse	NOUN
fnp-3528	144	58	abca12	abca12	NOUN
fnp-3528	144	59	inducers	inducer	NOUN
fnp-3528	145	1	ceramide	ceramide	VERB
fnp-3528	145	2	n	n	CCONJ
fnp-3528	145	3	-	-	PUNCT
fnp-3528	145	4	hexanoyl	hexanoyl	NOUN
fnp-3528	145	5	-	-	PUNCT
fnp-3528	145	6	d	d	NOUN
fnp-3528	145	7	-	-	PUNCT
fnp-3528	145	8	erythro	erythro	NOUN
fnp-3528	145	9	-	-	PUNCT
fnp-3528	145	10	sphingosine	sphingosine	NOUN
fnp-3528	145	11	ciglitazone	ciglitazone	NOUN
fnp-3528	145	12	d609	d609	PROPN
fnp-3528	145	13	xanthate	xanthate	VERB
fnp-3528	145	14	d	d	X
fnp-3528	145	15	-	-	PUNCT
fnp-3528	145	16	ddmp	ddmp	ADJ
fnp-3528	145	17	gi	gi	NOUN
fnp-3528	145	18	251929x	251929x	NUM
fnp-3528	145	19	gw610742	gw610742	PROPN
fnp-3528	145	20	d	d	PROPN
fnp-3528	145	21	-	-	PUNCT
fnp-3528	145	22	mapp	mapp	NOUN
fnp-3528	145	23	d	d	NOUN
fnp-3528	145	24	-	-	NOUN
fnp-3528	145	25	nmappd	nmappd	ADJ
fnp-3528	145	26	d	d	NOUN
fnp-3528	145	27	-	-	NOUN
fnp-3528	145	28	ppmp	ppmp	ADJ
fnp-3528	145	29	d	d	NOUN
fnp-3528	145	30	-	-	PUNCT
fnp-3528	145	31	pppp	pppp	NOUN
fnp-3528	145	32	22-(r)-hydroxycholesterol	22-(r)-hydroxycholesterol	NUM
fnp-3528	145	33	to901317	to901317	PROPN
fnp-3528	145	34	troglitazone	troglitazone	NOUN
fnp-3528	145	35	5	5	NUM
fnp-3528	145	36	µm	µm	ADP
fnp-3528	145	37	7.5	7.5	NUM
fnp-3528	145	38	µm	µm	ADP
fnp-3528	145	39	25	25	NUM
fnp-3528	145	40	µm	µm	ADP
fnp-3528	145	41	u.c.b	u.c.b	NOUN
fnp-3528	145	42	10	10	NUM
fnp-3528	145	43	µm	µm	NOUN
fnp-3528	145	44	8	8	NUM
fnp-3528	145	45	µm	µm	ADP
fnp-3528	145	46	10	10	NUM
fnp-3528	145	47	µm	µm	PART
fnp-3528	145	48	5	5	NUM
fnp-3528	145	49	µm	µm	ADP
fnp-3528	145	50	5	5	NUM
fnp-3528	145	51	µm	µm	ADP
fnp-3528	145	52	10	10	NUM
fnp-3528	145	53	µm	µm	PART
fnp-3528	145	54	10	10	NUM
fnp-3528	145	55	µm	µm	PART
fnp-3528	145	56	10	10	NUM
fnp-3528	145	57	µm	µm	ADP
fnp-3528	145	58	7.5	7.5	NUM
fnp-3528	145	59	µm	µm	ADP
fnp-3528	145	60	stabilizers	stabilizer	NOUN
fnp-3528	145	61	acitretin	acitretin	VERB
fnp-3528	145	62	1–10	1–10	PROPN
fnp-3528	145	63	mg	mg	PROPN
fnp-3528	145	64	/	/	SYM
fnp-3528	145	65	kg	kg	PROPN
fnp-3528	145	66	body	body	NOUN
fnp-3528	145	67	weight	weight	NOUN
fnp-3528	145	68	in	in	ADP
fnp-3528	145	69	pigs	pig	NOUN
fnp-3528	145	70	a	a	DET
fnp-3528	145	71	apart	apart	ADV
fnp-3528	145	72	from	from	ADP
fnp-3528	145	73	cholesterol	cholesterol	NOUN
fnp-3528	145	74	and/or	and/or	CCONJ
fnp-3528	145	75	phospholipids	phospholipid	NOUN
fnp-3528	145	76	b	b	X
fnp-3528	145	77	u.c	u.c	PROPN
fnp-3528	145	78	.	.	PUNCT
fnp-3528	145	79	=	=	PUNCT
fnp-3528	146	1	unspecified	unspecified	ADJ
fnp-3528	146	2	concentration	concentration	NOUN
fnp-3528	146	3	c	c	PROPN
fnp-3528	146	4	u.d	u.d	PROPN
fnp-3528	146	5	.	.	PUNCT
fnp-3528	147	1	=	=	SYM
fnp-3528	147	2	unspecified	unspecified	ADJ
fnp-3528	147	3	dose	dose	VERB
fnp-3528	147	4	inhibitors	inhibitor	NOUN
fnp-3528	147	5	to	to	ADP
fnp-3528	147	6	date	date	NOUN
fnp-3528	147	7	,	,	PUNCT
fnp-3528	147	8	the	the	DET
fnp-3528	147	9	number	number	NOUN
fnp-3528	147	10	of	of	ADP
fnp-3528	147	11	small	small	ADJ
fnp-3528	147	12	-	-	PUNCT
fnp-3528	147	13	molecules	molecule	NOUN
fnp-3528	147	14	that	that	PRON
fnp-3528	147	15	(	(	PUNCT
fnp-3528	147	16	are	be	AUX
fnp-3528	147	17	believed	believe	VERB
fnp-3528	147	18	to	to	PART
fnp-3528	147	19	)	)	PUNCT
fnp-3528	147	20	directly	directly	ADV
fnp-3528	147	21	interact	interact	VERB
fnp-3528	147	22	with	with	ADP
fnp-3528	147	23	abca	abca	NOUN
fnp-3528	147	24	transporters	transporter	NOUN
fnp-3528	147	25	is	be	AUX
fnp-3528	147	26	very	very	ADV
fnp-3528	147	27	low	low	ADJ
fnp-3528	147	28	.	.	PUNCT
fnp-3528	148	1	for	for	ADP
fnp-3528	148	2	example	example	NOUN
fnp-3528	148	3	,	,	PUNCT
fnp-3528	148	4	only	only	ADV
fnp-3528	148	5	14	14	NUM
fnp-3528	148	6	inhibitors	inhibitor	NOUN
fnp-3528	148	7	can	can	AUX
fnp-3528	148	8	be	be	AUX
fnp-3528	148	9	found	find	VERB
fnp-3528	148	10	in	in	ADP
fnp-3528	148	11	the	the	DET
fnp-3528	148	12	literature	literature	NOUN
fnp-3528	148	13	regarding	regard	VERB
fnp-3528	148	14	the	the	DET
fnp-3528	148	15	most	most	ADV
fnp-3528	148	16	studied	study	VERB
fnp-3528	148	17	prototype	prototype	NOUN
fnp-3528	148	18	of	of	ADP
fnp-3528	148	19	abca	abca	PROPN
fnp-3528	148	20	transporters	transporter	NOUN
fnp-3528	148	21	,	,	PUNCT
fnp-3528	148	22	abca1.245	abca1.245	PROPN
fnp-3528	148	23	-	-	PUNCT
fnp-3528	148	24	248	248	NUM
fnp-3528	148	25	only	only	ADV
fnp-3528	148	26	four	four	NUM
fnp-3528	148	27	of	of	ADP
fnp-3528	148	28	these	these	DET
fnp-3528	148	29	inhibitors	inhibitor	NOUN
fnp-3528	148	30	are	be	AUX
fnp-3528	148	31	associated	associate	VERB
fnp-3528	148	32	with	with	ADP
fnp-3528	148	33	half	half	ADV
fnp-3528	148	34	-	-	PUNCT
fnp-3528	148	35	maximal	maximal	ADJ
fnp-3528	148	36	inhibition	inhibition	NOUN
fnp-3528	148	37	concentrations	concentration	NOUN
fnp-3528	148	38	(	(	PUNCT
fnp-3528	148	39	ic50),245,249	ic50),245,249	X
fnp-3528	148	40	which	which	PRON
fnp-3528	148	41	is	be	AUX
fnp-3528	148	42	the	the	DET
fnp-3528	148	43	‘	'	PUNCT
fnp-3528	148	44	golden	golden	ADJ
fnp-3528	148	45	surrogate	surrogate	NOUN
fnp-3528	148	46	’	'	PUNCT
fnp-3528	148	47	to	to	PART
fnp-3528	148	48	evaluate	evaluate	VERB
fnp-3528	148	49	and	and	CCONJ
fnp-3528	148	50	judge	judge	VERB
fnp-3528	148	51	inhibitory	inhibitory	ADJ
fnp-3528	148	52	activities	activity	NOUN
fnp-3528	148	53	of	of	ADP
fnp-3528	148	54	small	small	ADJ
fnp-3528	148	55	-	-	PUNCT
fnp-3528	148	56	molecules	molecule	NOUN
fnp-3528	148	57	.	.	PUNCT
fnp-3528	149	1	the	the	DET
fnp-3528	149	2	following	follow	VERB
fnp-3528	149	3	section	section	NOUN
fnp-3528	149	4	will	will	AUX
fnp-3528	149	5	highlight	highlight	VERB
fnp-3528	149	6	these	these	DET
fnp-3528	149	7	small	small	ADJ
fnp-3528	149	8	-	-	PUNCT
fnp-3528	149	9	molecules	molecule	NOUN
fnp-3528	149	10	as	as	ADV
fnp-3528	149	11	well	well	ADV
fnp-3528	149	12	as	as	ADP
fnp-3528	149	13	inhibitors	inhibitor	NOUN
fnp-3528	149	14	of	of	ADP
fnp-3528	149	15	other	other	ADJ
fnp-3528	149	16	abca	abca	PROPN
fnp-3528	149	17	transporters	transporter	NOUN
fnp-3528	149	18	.	.	PUNCT
fnp-3528	150	1	abca1	abca1	NOUN
fnp-3528	150	2	glibenclamide	glibenclamide	NOUN
fnp-3528	150	3	and	and	CCONJ
fnp-3528	150	4	4,4’-diisothiocyano-2,2’-stilbenedisulfonic	4,4’-diisothiocyano-2,2’-stilbenedisulfonic	NUM
fnp-3528	150	5	acid	acid	NOUN
fnp-3528	150	6	(	(	PUNCT
fnp-3528	150	7	dids	dids	PROPN
fnp-3528	150	8	)	)	PUNCT
fnp-3528	150	9	as	as	SCONJ
fnp-3528	150	10	outlined	outline	VERB
fnp-3528	150	11	above	above	ADV
fnp-3528	150	12	,	,	PUNCT
fnp-3528	150	13	abca1	abca1	PROPN
fnp-3528	150	14	is	be	AUX
fnp-3528	150	15	the	the	DET
fnp-3528	150	16	most	most	ADV
fnp-3528	150	17	studied	study	VERB
fnp-3528	150	18	and	and	CCONJ
fnp-3528	150	19	understood	understand	VERB
fnp-3528	150	20	abca	abca	NOUN
fnp-3528	150	21	transporter	transporter	NOUN
fnp-3528	150	22	,	,	PUNCT
fnp-3528	150	23	although	although	SCONJ
fnp-3528	150	24	its	its	PRON
fnp-3528	150	25	particular	particular	ADJ
fnp-3528	150	26	role	role	NOUN
fnp-3528	150	27	in	in	ADP
fnp-3528	150	28	neurodegenerative	neurodegenerative	ADJ
fnp-3528	150	29	diseases	disease	NOUN
fnp-3528	150	30	in	in	ADP
fnp-3528	150	31	general51,103	general51,103	PROPN
fnp-3528	150	32	–	–	PUNCT
fnp-3528	150	33	and	and	CCONJ
fnp-3528	150	34	in	in	ADP
fnp-3528	150	35	ad	ad	NOUN
fnp-3528	150	36	in	in	ADP
fnp-3528	150	37	particular	particular	ADJ
fnp-3528	150	38	–	–	PUNCT
fnp-3528	150	39	is	be	AUX
fnp-3528	150	40	not	not	PART
fnp-3528	150	41	well	well	ADV
fnp-3528	150	42	understood.28	understood.28	ADJ
fnp-3528	150	43	-	-	PUNCT
fnp-3528	150	44	30,43,95,102	30,43,95,102	NUM
fnp-3528	150	45	however	however	ADV
fnp-3528	150	46	,	,	PUNCT
fnp-3528	150	47	over	over	ADP
fnp-3528	150	48	time	time	NOUN
fnp-3528	150	49	,	,	PUNCT
fnp-3528	150	50	several	several	ADJ
fnp-3528	150	51	agents	agent	NOUN
fnp-3528	150	52	were	be	AUX
fnp-3528	150	53	found	find	VERB
fnp-3528	150	54	to	to	PART
fnp-3528	150	55	impact	impact	VERB
fnp-3528	150	56	abca1	abca1	NOUN
fnp-3528	150	57	transport	transport	NOUN
fnp-3528	150	58	function	function	NOUN
fnp-3528	150	59	.	.	PUNCT
fnp-3528	151	1	the	the	DET
fnp-3528	151	2	most	most	ADV
fnp-3528	151	3	prominent	prominent	ADJ
fnp-3528	151	4	examples	example	NOUN
fnp-3528	151	5	are	be	AUX
fnp-3528	151	6	glibenclamide	glibenclamide	ADJ
fnp-3528	151	7	and	and	CCONJ
fnp-3528	151	8	dids	dids	PROPN
fnp-3528	151	9	(	(	PUNCT
fnp-3528	151	10	both	both	PRON
fnp-3528	151	11	figure	figure	VERB
fnp-3528	151	12	 	 	SPACE
fnp-3528	151	13	1	1	NUM
fnp-3528	151	14	)	)	PUNCT
fnp-3528	151	15	,	,	PUNCT
fnp-3528	151	16	which	which	PRON
fnp-3528	151	17	were	be	AUX
fnp-3528	151	18	first	first	ADV
fnp-3528	151	19	shown	show	VERB
fnp-3528	151	20	to	to	PART
fnp-3528	151	21	inhibit	inhibit	VERB
fnp-3528	151	22	abca1	abca1	NOUN
fnp-3528	151	23	in	in	ADP
fnp-3528	151	24	1997.247,248	1997.247,248	PUNCT
fnp-3528	151	25	these	these	DET
fnp-3528	151	26	drugs	drug	NOUN
fnp-3528	151	27	blocked	block	VERB
fnp-3528	151	28	the	the	DET
fnp-3528	151	29	abca1	abca1	NOUN
fnp-3528	151	30	-	-	PUNCT
fnp-3528	151	31	mediated	mediate	VERB
fnp-3528	151	32	125i	125i	NOUN
fnp-3528	151	33	efflux	efflux	VERB
fnp-3528	151	34	from	from	ADP
fnp-3528	151	35	murine	murine	ADJ
fnp-3528	151	36	peritoneal	peritoneal	ADJ
fnp-3528	151	37	macrophages247	macrophages247	PROPN
fnp-3528	151	38	as	as	ADV
fnp-3528	151	39	well	well	ADV
fnp-3528	151	40	as	as	ADP
fnp-3528	151	41	human	human	ADJ
fnp-3528	151	42	abca1	abca1	NOUN
fnp-3528	151	43	-	-	PUNCT
fnp-3528	151	44	transfected	transfecte	VERB
fnp-3528	151	45	xenopus	xenopus	PROPN
fnp-3528	151	46	laevis	laevis	X
fnp-3528	151	47	oocytes.248	oocytes.248	PROPN
fnp-3528	151	48	glibenclamide	glibenclamide	ADV
fnp-3528	151	49	and	and	CCONJ
fnp-3528	151	50	dids	dids	PROPN
fnp-3528	151	51	inhibited	inhibit	VERB
fnp-3528	151	52	the	the	DET
fnp-3528	151	53	abca1	abca1	NOUN
fnp-3528	151	54	-	-	PUNCT
fnp-3528	151	55	mediated	mediate	VERB
fnp-3528	151	56	transport	transport	NOUN
fnp-3528	151	57	of	of	ADP
fnp-3528	151	58	cholesterol	cholesterol	NOUN
fnp-3528	151	59	and	and	CCONJ
fnp-3528	151	60	other	other	ADJ
fnp-3528	151	61	sterols	sterol	NOUN
fnp-3528	151	62	as	as	ADV
fnp-3528	151	63	well	well	ADV
fnp-3528	151	64	as	as	ADP
fnp-3528	151	65	phosphoand	phosphoand	NOUN
fnp-3528	151	66	sphingolipids	sphingolipid	NOUN
fnp-3528	151	67	.	.	PUNCT
fnp-3528	152	1	thus	thus	ADV
fnp-3528	152	2	,	,	PUNCT
fnp-3528	152	3	these	these	DET
fnp-3528	152	4	agents	agent	NOUN
fnp-3528	152	5	became	become	VERB
fnp-3528	152	6	the	the	DET
fnp-3528	152	7	‘	'	PUNCT
fnp-3528	152	8	standard	standard	ADJ
fnp-3528	152	9	abca1	abca1	NOUN
fnp-3528	152	10	inhibitors	inhibitor	NOUN
fnp-3528	152	11	’	'	PUNCT
fnp-3528	152	12	and	and	CCONJ
fnp-3528	152	13	have	have	AUX
fnp-3528	152	14	frequently	frequently	ADV
fnp-3528	152	15	been	be	AUX
fnp-3528	152	16	used	use	VERB
fnp-3528	152	17	in	in	ADP
fnp-3528	152	18	abca1	abca1	NOUN
fnp-3528	152	19	studies	study	NOUN
fnp-3528	152	20	ever	ever	ADV
fnp-3528	152	21	since.229,250	since.229,250	NOUN
fnp-3528	152	22	-	-	PUNCT
fnp-3528	152	23	269	269	NUM
fnp-3528	152	24	glibenclamide	glibenclamide	NOUN
fnp-3528	152	25	and	and	CCONJ
fnp-3528	152	26	dids	did	NOUN
fnp-3528	152	27	were	be	AUX
fnp-3528	152	28	preferred	prefer	VERB
fnp-3528	152	29	over	over	ADP
fnp-3528	152	30	other	other	ADJ
fnp-3528	152	31	discovered	discover	VERB
fnp-3528	152	32	abca	abca	NOUN
fnp-3528	152	33	inhibitors	inhibitor	NOUN
fnp-3528	152	34	,	,	PUNCT
fnp-3528	152	35	such	such	ADJ
fnp-3528	152	36	as	as	ADP
fnp-3528	152	37	bumetanide	bumetanide	ADJ
fnp-3528	152	38	,	,	PUNCT
fnp-3528	152	39	diphenylamine	diphenylamine	NOUN
fnp-3528	152	40	2	2	NUM
fnp-3528	152	41	-	-	PUNCT
fnp-3528	152	42	carboxylic	carboxylic	ADJ
fnp-3528	152	43	acid	acid	NOUN
fnp-3528	152	44	,	,	PUNCT
fnp-3528	152	45	flufenamic	flufenamic	ADJ
fnp-3528	152	46	acid	acid	NOUN
fnp-3528	152	47	,	,	PUNCT
fnp-3528	152	48	furosemide	furosemide	ADJ
fnp-3528	152	49	,	,	PUNCT
fnp-3528	152	50	and	and	CCONJ
fnp-3528	152	51	bromosulfophthaleine.248	bromosulfophthaleine.248	VERB
fnp-3528	152	52	specifically	specifically	ADV
fnp-3528	152	53	glibenclamide	glibenclamide	ADJ
fnp-3528	152	54	was	be	AUX
fnp-3528	152	55	rigorously	rigorously	ADV
fnp-3528	152	56	evaluated	evaluate	VERB
fnp-3528	152	57	regarding	regard	VERB
fnp-3528	152	58	its	its	PRON
fnp-3528	152	59	mechanism	mechanism	NOUN
fnp-3528	152	60	of	of	ADP
fnp-3528	152	61	action	action	NOUN
fnp-3528	152	62	.	.	PUNCT
fnp-3528	153	1	it	it	PRON
fnp-3528	153	2	was	be	AUX
fnp-3528	153	3	demonstrated	demonstrate	VERB
fnp-3528	153	4	that	that	SCONJ
fnp-3528	153	5	glibenclamide	glibenclamide	NOUN
fnp-3528	153	6	prevented	prevent	VERB
fnp-3528	153	7	cross	cross	ADJ
fnp-3528	153	8	-	-	ADJ
fnp-3528	153	9	linking	linking	NOUN
fnp-3528	153	10	of	of	ADP
fnp-3528	153	11	125i	125i	NOUN
fnp-3528	153	12	-	-	PUNCT
fnp-3528	153	13	marked	mark	VERB
fnp-3528	153	14	apoa1	apoa1	PROPN
fnp-3528	153	15	to	to	PART
fnp-3528	153	16	abca1,267,270	abca1,267,270	VERB
fnp-3528	153	17	not	not	PART
fnp-3528	153	18	interfering	interfere	VERB
fnp-3528	153	19	with	with	ADP
fnp-3528	153	20	abca1	abca1	NOUN
fnp-3528	153	21	location	location	NOUN
fnp-3528	153	22	at	at	ADP
fnp-3528	153	23	the	the	DET
fnp-3528	153	24	cell	cell	NOUN
fnp-3528	153	25	surface.267	surface.267	NOUN
fnp-3528	153	26	in	in	ADP
fnp-3528	153	27	essence	essence	NOUN
fnp-3528	153	28	,	,	PUNCT
fnp-3528	153	29	glibenclamide	glibenclamide	NOUN
fnp-3528	153	30	and	and	CCONJ
fnp-3528	153	31	dids	did	NOUN
fnp-3528	153	32	may	may	AUX
fnp-3528	153	33	play	play	VERB
fnp-3528	153	34	a	a	DET
fnp-3528	153	35	significant	significant	ADJ
fnp-3528	153	36	role	role	NOUN
fnp-3528	153	37	in	in	ADP
fnp-3528	153	38	the	the	DET
fnp-3528	153	39	development	development	NOUN
fnp-3528	153	40	of	of	ADP
fnp-3528	153	41	future	future	ADJ
fnp-3528	153	42	modulators	modulator	NOUN
fnp-3528	153	43	of	of	ADP
fnp-3528	153	44	abca	abca	NOUN
fnp-3528	153	45	transporters	transporter	NOUN
fnp-3528	153	46	in	in	ADP
fnp-3528	153	47	general	general	ADJ
fnp-3528	153	48	.	.	PUNCT
fnp-3528	154	1	probucol	probucol	PROPN
fnp-3528	154	2	and	and	CCONJ
fnp-3528	154	3	cyclosporine	cyclosporine	VERB
fnp-3528	154	4	a	a	DET
fnp-3528	154	5	less	less	ADV
fnp-3528	154	6	prominent	prominent	ADJ
fnp-3528	154	7	but	but	CCONJ
fnp-3528	154	8	also	also	ADV
fnp-3528	154	9	well	well	INTJ
fnp-3528	154	10	characterized	characterize	VERB
fnp-3528	154	11	are	be	AUX
fnp-3528	154	12	the	the	DET
fnp-3528	154	13	antilipidemic	antilipidemic	ADJ
fnp-3528	154	14	drug	drug	NOUN
fnp-3528	154	15	probucol246,271	probucol246,271	NOUN
fnp-3528	154	16	-	-	SYM
fnp-3528	154	17	278	278	NUM
fnp-3528	154	18	and	and	CCONJ
fnp-3528	154	19	the	the	DET
fnp-3528	154	20	immunosuppressant	immunosuppressant	ADJ
fnp-3528	154	21	cyclosporine	cyclosporine	VERB
fnp-3528	154	22	a245,249,258,279	a245,249,258,279	PROPN
fnp-3528	154	23	-	-	PUNCT
fnp-3528	154	24	281	281	NUM
fnp-3528	154	25	(	(	PUNCT
fnp-3528	154	26	both	both	PRON
fnp-3528	154	27	figure	figure	VERB
fnp-3528	154	28	 	 	SPACE
fnp-3528	154	29	1	1	NUM
fnp-3528	154	30	)	)	PUNCT
fnp-3528	154	31	.	.	PUNCT
fnp-3528	155	1	probucol	probucol	PROPN
fnp-3528	155	2	was	be	AUX
fnp-3528	155	3	demonstrated	demonstrate	VERB
fnp-3528	155	4	to	to	PART
fnp-3528	155	5	reduce	reduce	VERB
fnp-3528	155	6	the	the	DET
fnp-3528	155	7	cholesterol	cholesterol	NOUN
fnp-3528	155	8	efflux	efflux	NOUN
fnp-3528	155	9	from	from	ADP
fnp-3528	155	10	different	different	ADJ
fnp-3528	155	11	abca1	abca1	NOUN
fnp-3528	155	12	-	-	PUNCT
fnp-3528	155	13	overexpressing	overexpresse	VERB
fnp-3528	155	14	murine	murine	ADJ
fnp-3528	155	15	and	and	CCONJ
fnp-3528	155	16	human	human	ADJ
fnp-3528	155	17	macrophages,275	macrophages,275	PROPN
fnp-3528	155	18	-	-	PUNCT
fnp-3528	155	19	278	278	NUM
fnp-3528	155	20	and	and	CCONJ
fnp-3528	155	21	total	total	ADJ
fnp-3528	155	22	lipid	lipid	NOUN
fnp-3528	155	23	release	release	NOUN
fnp-3528	155	24	(	(	PUNCT
fnp-3528	155	25	cholesterol	cholesterol	NOUN
fnp-3528	155	26	+	+	CCONJ
fnp-3528	155	27	phospholipids	phospholipid	NOUN
fnp-3528	155	28	)	)	PUNCT
fnp-3528	155	29	from	from	ADP
fnp-3528	155	30	human	human	PROPN
fnp-3528	155	31	wi-38	wi-38	PROPN
fnp-3528	155	32	fibroblasts.246	fibroblasts.246	PROPN
fnp-3528	155	33	vice	vice	PROPN
fnp-3528	155	34	versa	versa	ADV
fnp-3528	155	35	,	,	PUNCT
fnp-3528	155	36	probucol	probucol	PROPN
fnp-3528	155	37	increased	increase	VERB
fnp-3528	155	38	accumulation	accumulation	NOUN
fnp-3528	155	39	of	of	ADP
fnp-3528	155	40	free	free	ADJ
fnp-3528	155	41	cholesterol	cholesterol	NOUN
fnp-3528	155	42	,	,	PUNCT
fnp-3528	155	43	cholesterol	cholesterol	NOUN
fnp-3528	155	44	esters	ester	NOUN
fnp-3528	155	45	,	,	PUNCT
fnp-3528	155	46	phosphatidylcholine	phosphatidylcholine	NOUN
fnp-3528	155	47	,	,	PUNCT
fnp-3528	155	48	and	and	CCONJ
fnp-3528	155	49	sphingomyelin	sphingomyelin	NOUN
fnp-3528	155	50	in	in	ADP
fnp-3528	155	51	human	human	PROPN
fnp-3528	155	52	fibroblasts.246	fibroblasts.246	PROPN
fnp-3528	155	53	additionally	additionally	ADV
fnp-3528	155	54	,	,	PUNCT
fnp-3528	155	55	probucol	probucol	PROPN
fnp-3528	155	56	was	be	AUX
fnp-3528	155	57	reported	report	VERB
fnp-3528	155	58	to	to	PART
fnp-3528	155	59	prevent	prevent	VERB
fnp-3528	155	60	cell	cell	NOUN
fnp-3528	155	61	surface	surface	NOUN
fnp-3528	155	62	-	-	PUNCT
fnp-3528	155	63	specific	specific	ADJ
fnp-3528	155	64	binding	binding	NOUN
fnp-3528	155	65	of	of	ADP
fnp-3528	155	66	125i	125i	NOUN
fnp-3528	155	67	marked	mark	VERB
fnp-3528	155	68	apoa1	apoa1	PROPN
fnp-3528	155	69	to	to	ADP
fnp-3528	155	70	abca1.246,278	abca1.246,278	PROPN
fnp-3528	155	71	similarly	similarly	ADV
fnp-3528	155	72	,	,	PUNCT
fnp-3528	155	73	this	this	DET
fnp-3528	155	74	effect	effect	NOUN
fnp-3528	155	75	has	have	AUX
fnp-3528	155	76	already	already	ADV
fnp-3528	155	77	been	be	AUX
fnp-3528	155	78	demonstrated	demonstrate	VERB
fnp-3528	155	79	for	for	ADP
fnp-3528	155	80	glibenclamide	glibenclamide	ADJ
fnp-3528	155	81	before.267,270	before.267,270	NOUN
fnp-3528	155	82	interestingly	interestingly	ADV
fnp-3528	155	83	,	,	PUNCT
fnp-3528	155	84	it	it	PRON
fnp-3528	155	85	was	be	AUX
fnp-3528	155	86	shown	show	VERB
fnp-3528	155	87	that	that	SCONJ
fnp-3528	155	88	total	total	ADJ
fnp-3528	155	89	abca1	abca1	NOUN
fnp-3528	155	90	protein	protein	NOUN
fnp-3528	155	91	levels	level	NOUN
fnp-3528	155	92	were	be	AUX
fnp-3528	155	93	increased	increase	VERB
fnp-3528	155	94	after	after	ADP
fnp-3528	155	95	exposure	exposure	NOUN
fnp-3528	155	96	to	to	ADP
fnp-3528	155	97	probucol	probucol	PROPN
fnp-3528	155	98	due	due	ADJ
fnp-3528	155	99	to	to	PART
fnp-3528	155	100	decreased	decrease	VERB
fnp-3528	155	101	degradation.246,275	degradation.246,275	ADP
fnp-3528	155	102	this	this	PRON
fnp-3528	155	103	qualifies	qualify	VERB
fnp-3528	155	104	probucol	probucol	PROPN
fnp-3528	155	105	also	also	ADV
fnp-3528	155	106	as	as	ADP
fnp-3528	155	107	a	a	DET
fnp-3528	155	108	stabilizer	stabilizer	NOUN
fnp-3528	155	109	.	.	PUNCT
fnp-3528	156	1	however	however	ADV
fnp-3528	156	2	,	,	PUNCT
fnp-3528	156	3	as	as	SCONJ
fnp-3528	156	4	its	its	PRON
fnp-3528	156	5	inhibiting	inhibit	VERB
fnp-3528	156	6	effect	effect	NOUN
fnp-3528	156	7	is	be	AUX
fnp-3528	156	8	far	far	ADV
fnp-3528	156	9	more	more	ADV
fnp-3528	156	10	pronounced	pronounce	VERB
fnp-3528	156	11	,	,	PUNCT
fnp-3528	156	12	we	we	PRON
fnp-3528	156	13	have	have	AUX
fnp-3528	156	14	included	include	VERB
fnp-3528	156	15	it	it	PRON
fnp-3528	156	16	as	as	ADP
fnp-3528	156	17	an	an	DET
fnp-3528	156	18	inhibitor	inhibitor	NOUN
fnp-3528	156	19	here	here	ADV
fnp-3528	156	20	.	.	PUNCT
fnp-3528	157	1	the	the	DET
fnp-3528	157	2	immunosuppressant	immunosuppressant	PROPN
fnp-3528	157	3	cyclosporine	cyclosporine	PROPN
fnp-3528	157	4	a	a	PRON
fnp-3528	157	5	has	have	AUX
fnp-3528	157	6	been	be	AUX
fnp-3528	157	7	characterized	characterize	VERB
fnp-3528	157	8	as	as	ADP
fnp-3528	157	9	an	an	DET
fnp-3528	157	10	abca1	abca1	NOUN
fnp-3528	157	11	inhibitor	inhibitor	NOUN
fnp-3528	157	12	in	in	ADP
fnp-3528	157	13	multiple	multiple	ADJ
fnp-3528	157	14	studies.245,249,258,279	studies.245,249,258,279	NOUN
fnp-3528	157	15	-	-	SYM
fnp-3528	157	16	281	281	NUM
fnp-3528	157	17	this	this	DET
fnp-3528	157	18	inhibition	inhibition	NOUN
fnp-3528	157	19	was	be	AUX
fnp-3528	157	20	shown	show	VERB
fnp-3528	157	21	to	to	PART
fnp-3528	157	22	be	be	AUX
fnp-3528	157	23	direct	direct	ADJ
fnp-3528	157	24	through	through	ADP
fnp-3528	157	25	a	a	DET
fnp-3528	157	26	radiolabeled	radiolabele	VERB
fnp-3528	157	27	variant	variant	NOUN
fnp-3528	157	28	of	of	ADP
fnp-3528	157	29	cyclosporine	cyclosporine	PROPN
fnp-3528	158	1	a	a	DET
fnp-3528	158	2	and	and	CCONJ
fnp-3528	158	3	purified	purified	ADJ
fnp-3528	158	4	abca1.245	abca1.245	PROPN
fnp-3528	158	5	cyclosporine	cyclosporine	VERB
fnp-3528	158	6	a	a	DET
fnp-3528	158	7	not	not	PART
fnp-3528	158	8	only	only	ADV
fnp-3528	158	9	functionally	functionally	ADV
fnp-3528	158	10	inhibited	inhibit	VERB
fnp-3528	158	11	abca1	abca1	NOUN
fnp-3528	158	12	-	-	PUNCT
fnp-3528	158	13	mediated	mediate	VERB
fnp-3528	158	14	cholesterol	cholesterol	NOUN
fnp-3528	158	15	and	and	CCONJ
fnp-3528	158	16	phospholipid	phospholipid	NOUN
fnp-3528	158	17	efflux,245,249	efflux,245,249	NOUN
fnp-3528	158	18	and	and	CCONJ
fnp-3528	158	19	caused	cause	VERB
fnp-3528	158	20	intracellular	intracellular	ADJ
fnp-3528	158	21	accumulation	accumulation	NOUN
fnp-3528	158	22	of	of	ADP
fnp-3528	158	23	cholesterol,258	cholesterol,258	INTJ
fnp-3528	158	24	but	but	CCONJ
fnp-3528	158	25	also	also	ADV
fnp-3528	158	26	inhibited	inhibit	VERB
fnp-3528	158	27	the	the	DET
fnp-3528	158	28	abca1	abca1	NOUN
fnp-3528	158	29	-	-	PUNCT
fnp-3528	158	30	dependent	dependent	ADJ
fnp-3528	158	31	binding	binding	NOUN
fnp-3528	158	32	of	of	ADP
fnp-3528	158	33	alexa	alexa	PROPN
fnp-3528	158	34	546or	546or	PROPN
fnp-3528	158	35	125i	125i	NOUN
fnp-3528	158	36	-	-	PUNCT
fnp-3528	158	37	labeled	label	VERB
fnp-3528	158	38	apoa1,245,249	apoa1,245,249	X
fnp-3528	158	39	as	as	SCONJ
fnp-3528	158	40	demonstrated	demonstrate	VERB
fnp-3528	158	41	for	for	ADP
fnp-3528	158	42	glibenclamide267,270	glibenclamide267,270	NUM
fnp-3528	158	43	and	and	CCONJ
fnp-3528	158	44	probucol246,278	probucol246,278	ADJ
fnp-3528	158	45	before	before	ADV
fnp-3528	158	46	.	.	PUNCT
fnp-3528	159	1	interestingly	interestingly	ADV
fnp-3528	159	2	,	,	PUNCT
fnp-3528	159	3	toxicity	toxicity	NOUN
fnp-3528	159	4	assays	assay	NOUN
fnp-3528	159	5	demonstrated	demonstrate	VERB
fnp-3528	159	6	that	that	SCONJ
fnp-3528	159	7	cyclosporine	cyclosporine	NOUN
fnp-3528	159	8	a	a	PRON
fnp-3528	159	9	negated	negate	VERB
fnp-3528	159	10	the	the	DET
fnp-3528	159	11	positive	positive	ADJ
fnp-3528	159	12	effect	effect	NOUN
fnp-3528	159	13	of	of	ADP
fnp-3528	159	14	an	an	DET
fnp-3528	159	15	abca1	abca1	NOUN
fnp-3528	159	16	inducer	inducer	NOUN
fnp-3528	159	17	on	on	ADP
fnp-3528	159	18	cell	cell	NOUN
fnp-3528	159	19	viability	viability	NOUN
fnp-3528	159	20	when	when	SCONJ
fnp-3528	159	21	cells	cell	NOUN
fnp-3528	159	22	were	be	AUX
fnp-3528	159	23	exposed	expose	VERB
fnp-3528	159	24	to	to	ADP
fnp-3528	159	25	aβ	aβ	PRON
fnp-3528	159	26	proteins.280	proteins.280	VERB
fnp-3528	159	27	this	this	PRON
fnp-3528	159	28	was	be	AUX
fnp-3528	159	29	confirmed	confirm	VERB
fnp-3528	159	30	in	in	ADP
fnp-3528	159	31	vivo	vivo	NOUN
fnp-3528	159	32	in	in	ADP
fnp-3528	159	33	c57bl/6	c57bl/6	NOUN
fnp-3528	159	34	mice	mouse	NOUN
fnp-3528	159	35	that	that	PRON
fnp-3528	159	36	had	have	AUX
fnp-3528	159	37	reduced	reduce	VERB
fnp-3528	159	38	hdl	hdl	PROPN
fnp-3528	159	39	levels.249	levels.249	PROPN
fnp-3528	159	40	interestingly	interestingly	ADV
fnp-3528	159	41	,	,	PUNCT
fnp-3528	159	42	cyclosporine	cyclosporine	VERB
fnp-3528	159	43	a	a	PRON
fnp-3528	159	44	was	be	AUX
fnp-3528	159	45	shown	show	VERB
fnp-3528	159	46	to	to	PART
fnp-3528	159	47	decrease	decrease	VERB
fnp-3528	159	48	abca1	abca1	NOUN
fnp-3528	159	49	turnover	turnover	NOUN
fnp-3528	159	50	,	,	PUNCT
fnp-3528	159	51	increasing	increase	VERB
fnp-3528	159	52	its	its	PRON
fnp-3528	159	53	presence	presence	NOUN
fnp-3528	159	54	at	at	ADP
fnp-3528	159	55	the	the	DET
fnp-3528	159	56	cell	cell	NOUN
fnp-3528	159	57	surface	surface	NOUN
fnp-3528	159	58	by	by	ADP
fnp-3528	159	59	a	a	DET
fnp-3528	159	60	factor	factor	NOUN
fnp-3528	159	61	of	of	ADP
fnp-3528	159	62	two	two	NUM
fnp-3528	159	63	as	as	SCONJ
fnp-3528	159	64	demonstrated	demonstrate	VERB
fnp-3528	159	65	with	with	ADP
fnp-3528	159	66	a	a	DET
fnp-3528	159	67	gfp	gfp	PROPN
fnp-3528	159	68	-	-	PUNCT
fnp-3528	159	69	labeled	label	VERB
fnp-3528	159	70	abca1	abca1	NOUN
fnp-3528	159	71	variant,249	variant,249	NOUN
fnp-3528	159	72	suggesting	suggest	VERB
fnp-3528	159	73	a	a	DET
fnp-3528	159	74	similar	similar	ADJ
fnp-3528	159	75	mode	mode	NOUN
fnp-3528	159	76	of	of	ADP
fnp-3528	159	77	inhibition	inhibition	NOUN
fnp-3528	159	78	as	as	ADP
fnp-3528	159	79	for	for	ADP
fnp-3528	159	80	probucol.275	probucol.275	PROPN
fnp-3528	159	81	thus	thus	ADV
fnp-3528	159	82	,	,	PUNCT
fnp-3528	159	83	as	as	SCONJ
fnp-3528	159	84	for	for	ADP
fnp-3528	159	85	probucol,246,275	probucol,246,275	NOUN
fnp-3528	159	86	cyclosporine	cyclosporine	VERB
fnp-3528	159	87	a	a	PRON
fnp-3528	159	88	also	also	ADV
fnp-3528	159	89	appears	appear	VERB
fnp-3528	159	90	to	to	PART
fnp-3528	159	91	have	have	VERB
fnp-3528	159	92	a	a	DET
fnp-3528	159	93	stabilizer	stabilizer	NOUN
fnp-3528	159	94	function,275	function,275	NOUN
fnp-3528	159	95	but	but	CCONJ
fnp-3528	159	96	is	be	AUX
fnp-3528	159	97	included	include	VERB
fnp-3528	159	98	in	in	ADP
fnp-3528	159	99	the	the	DET
fnp-3528	159	100	current	current	ADJ
fnp-3528	159	101	section	section	NOUN
fnp-3528	159	102	due	due	ADP
fnp-3528	159	103	to	to	ADP
fnp-3528	159	104	its	its	PRON
fnp-3528	159	105	pronounced	pronounced	ADJ
fnp-3528	159	106	inhibitory	inhibitory	ADJ
fnp-3528	159	107	role	role	NOUN
fnp-3528	159	108	.	.	PUNCT
fnp-3528	160	1	morevover	morevover	ADV
fnp-3528	160	2	,	,	PUNCT
fnp-3528	160	3	the	the	DET
fnp-3528	160	4	cyclosporine	cyclosporine	NOUN
fnp-3528	160	5	a	a	DET
fnp-3528	160	6	analog	analog	NOUN
fnp-3528	160	7	valspodar	valspodar	NOUN
fnp-3528	160	8	(	(	PUNCT
fnp-3528	160	9	psc833	psc833	PROPN
fnp-3528	160	10	)	)	PUNCT
fnp-3528	160	11	inhibited	inhibit	VERB
fnp-3528	160	12	direct	direct	ADJ
fnp-3528	160	13	binding	binding	NOUN
fnp-3528	160	14	of	of	ADP
fnp-3528	160	15	radiolabeled	radiolabele	VERB
fnp-3528	160	16	cyclosporine	cyclosporine	NOUN
fnp-3528	160	17	a	a	PRON
fnp-3528	160	18	to	to	ADP
fnp-3528	160	19	abca1	abca1	NOUN
fnp-3528	160	20	,	,	PUNCT
fnp-3528	160	21	revealing	reveal	VERB
fnp-3528	160	22	that	that	DET
fnp-3528	160	23	valspodar	valspodar	NOUN
fnp-3528	160	24	also	also	ADV
fnp-3528	160	25	acts	act	VERB
fnp-3528	160	26	as	as	ADP
fnp-3528	160	27	an	an	DET
fnp-3528	160	28	abca1	abca1	NOUN
fnp-3528	161	1	inhibitor.245,282	inhibitor.245,282	ADJ
fnp-3528	161	2	furthermore	furthermore	ADV
fnp-3528	161	3	,	,	PUNCT
fnp-3528	161	4	several	several	ADJ
fnp-3528	161	5	other	other	ADJ
fnp-3528	161	6	calmodulin	calmodulin	NOUN
fnp-3528	161	7	antagonists	antagonist	NOUN
fnp-3528	161	8	inhibited	inhibit	VERB
fnp-3528	161	9	abca1	abca1	NOUN
fnp-3528	161	10	-	-	PUNCT
fnp-3528	161	11	mediated	mediate	VERB
fnp-3528	161	12	cholesterol	cholesterol	NOUN
fnp-3528	161	13	efflux	efflux	NOUN
fnp-3528	161	14	and	and	CCONJ
fnp-3528	161	15	binding	bind	VERB
fnp-3528	161	16	of	of	ADP
fnp-3528	161	17	apoa1.245	apoa1.245	ADJ
fnp-3528	161	18	these	these	PRON
fnp-3528	161	19	include	include	VERB
fnp-3528	161	20	pimecrolimus,245	pimecrolimus,245	PROPN
fnp-3528	161	21	sirolimus,245	sirolimus,245	PROPN
fnp-3528	161	22	and	and	CCONJ
fnp-3528	161	23	tacrolimus,245	tacrolimus,245	PROPN
fnp-3528	161	24	suggesting	suggest	VERB
fnp-3528	161	25	these	these	DET
fnp-3528	161	26	molecules	molecule	NOUN
fnp-3528	161	27	as	as	ADP
fnp-3528	161	28	potential	potential	ADJ
fnp-3528	161	29	scaffolds	scaffold	NOUN
fnp-3528	161	30	for	for	ADP
fnp-3528	161	31	the	the	DET
fnp-3528	161	32	development	development	NOUN
fnp-3528	161	33	of	of	ADP
fnp-3528	161	34	future	future	ADJ
fnp-3528	161	35	abca1	abca1	NOUN
fnp-3528	161	36	modulators	modulator	NOUN
fnp-3528	161	37	.	.	PUNCT
fnp-3528	162	1	other	other	ADJ
fnp-3528	162	2	abca1	abca1	NOUN
fnp-3528	162	3	inhibitors	inhibitor	NOUN
fnp-3528	162	4	in	in	ADP
fnp-3528	162	5	terms	term	NOUN
fnp-3528	162	6	of	of	ADP
fnp-3528	162	7	other	other	ADJ
fnp-3528	162	8	small	small	ADJ
fnp-3528	162	9	-	-	PUNCT
fnp-3528	162	10	molecules	molecule	NOUN
fnp-3528	162	11	that	that	PRON
fnp-3528	162	12	were	be	AUX
fnp-3528	162	13	suggested	suggest	VERB
fnp-3528	162	14	to	to	PART
fnp-3528	162	15	inhibit	inhibit	VERB
fnp-3528	162	16	abca1	abca1	NOUN
fnp-3528	162	17	function	function	NOUN
fnp-3528	162	18	,	,	PUNCT
fnp-3528	162	19	blt-4	blt-4	PUNCT
fnp-3528	162	20	has	have	AUX
fnp-3528	162	21	been	be	AUX
fnp-3528	162	22	demonstrated	demonstrate	VERB
fnp-3528	162	23	to	to	PART
fnp-3528	162	24	inhibit	inhibit	VERB
fnp-3528	162	25	cholesterol	cholesterol	NOUN
fnp-3528	162	26	and	and	CCONJ
fnp-3528	162	27	phospholipid	phospholipid	NOUN
fnp-3528	162	28	export	export	NOUN
fnp-3528	162	29	from	from	ADP
fnp-3528	162	30	adipocytes	adipocyte	NOUN
fnp-3528	162	31	and	and	CCONJ
fnp-3528	162	32	macrophages,255	macrophages,255	X
fnp-3528	162	33	and	and	CCONJ
fnp-3528	162	34	to	to	PART
fnp-3528	162	35	decrease	decrease	VERB
fnp-3528	162	36	cholesterol	cholesterol	NOUN
fnp-3528	162	37	efflux	efflux	VERB
fnp-3528	162	38	from	from	ADP
fnp-3528	162	39	abca1	abca1	NOUN
fnp-3528	162	40	-	-	PUNCT
fnp-3528	162	41	transfected	transfecte	VERB
fnp-3528	162	42	hek293	hek293	PROPN
fnp-3528	162	43	cells	cell	NOUN
fnp-3528	162	44	.	.	PUNCT
fnp-3528	163	1	blt-4	blt-4	PRON
fnp-3528	163	2	was	be	AUX
fnp-3528	163	3	also	also	ADV
fnp-3528	163	4	shown	show	VERB
fnp-3528	163	5	to	to	PART
fnp-3528	163	6	inhibit	inhibit	VERB
fnp-3528	163	7	125i	125i	NOUN
fnp-3528	163	8	-	-	PUNCT
fnp-3528	163	9	marked	mark	VERB
fnp-3528	163	10	apoa1	apoa1	NOUN
fnp-3528	163	11	-	-	ADJ
fnp-3528	163	12	binding	bind	VERB
fnp-3528	163	13	to	to	PART
fnp-3528	163	14	abca1,270	abca1,270	PROPN
fnp-3528	163	15	as	as	SCONJ
fnp-3528	163	16	demonstrated	demonstrate	VERB
fnp-3528	163	17	for	for	ADP
fnp-3528	163	18	glibenclamide,267,270	glibenclamide,267,270	PROPN
fnp-3528	163	19	probucol,246,278	probucol,246,278	NOUN
fnp-3528	163	20	and	and	CCONJ
fnp-3528	163	21	cyclosporine.245,249	cyclosporine.245,249	PROPN
fnp-3528	163	22	other	other	ADJ
fnp-3528	163	23	abca	abca	PROPN
fnp-3528	163	24	transporters	transporter	NOUN
fnp-3528	163	25	while	while	SCONJ
fnp-3528	163	26	abca1	abca1	NOUN
fnp-3528	163	27	can	can	AUX
fnp-3528	163	28	be	be	AUX
fnp-3528	163	29	considered	consider	VERB
fnp-3528	163	30	a	a	DET
fnp-3528	163	31	less	less	ADV
fnp-3528	163	32	-	-	PUNCT
fnp-3528	163	33	studied	study	VERB
fnp-3528	163	34	abc	abc	PROPN
fnp-3528	163	35	transporter	transporter	VERB
fnp-3528	163	36	with	with	ADP
fnp-3528	163	37	certain	certain	ADJ
fnp-3528	163	38	knowledge	knowledge	NOUN
fnp-3528	163	39	about	about	ADP
fnp-3528	163	40	its	its	PRON
fnp-3528	163	41	function	function	NOUN
fnp-3528	163	42	and	and	CCONJ
fnp-3528	163	43	interfering	interfere	VERB
fnp-3528	163	44	small	small	ADJ
fnp-3528	163	45	-	-	PUNCT
fnp-3528	163	46	molecules,18	molecules,18	NOUN
fnp-3528	163	47	all	all	DET
fnp-3528	163	48	other	other	ADJ
fnp-3528	163	49	abca	abca	NOUN
fnp-3528	163	50	transporters	transporter	NOUN
fnp-3528	163	51	belong	belong	VERB
fnp-3528	163	52	to	to	ADP
fnp-3528	163	53	the	the	DET
fnp-3528	163	54	group	group	NOUN
fnp-3528	163	55	of	of	ADP
fnp-3528	163	56	under	under	ADV
fnp-3528	163	57	-	-	PUNCT
fnp-3528	163	58	studied	study	VERB
fnp-3528	163	59	abc	abc	PROPN
fnp-3528	163	60	transporters	transporter	NOUN
fnp-3528	163	61	that	that	PRON
fnp-3528	163	62	can	can	AUX
fnp-3528	163	63	not	not	PART
fnp-3528	163	64	be	be	AUX
fnp-3528	163	65	addressed	address	VERB
fnp-3528	163	66	by	by	ADP
fnp-3528	163	67	small	small	ADJ
fnp-3528	163	68	-	-	PUNCT
fnp-3528	163	69	molecules	molecule	NOUN
fnp-3528	163	70	with	with	ADP
fnp-3528	163	71	very	very	ADV
fnp-3528	163	72	rare	rare	ADJ
fnp-3528	163	73	exceptions.18	exceptions.18	NOUN
fnp-3528	163	74	one	one	NUM
fnp-3528	163	75	rare	rare	ADJ
fnp-3528	163	76	example	example	NOUN
fnp-3528	163	77	is	be	AUX
fnp-3528	163	78	abca8	abca8	PROPN
fnp-3528	163	79	.	.	PUNCT
fnp-3528	164	1	using	use	VERB
fnp-3528	164	2	the	the	DET
fnp-3528	164	3	xenopus	xenopus	PROPN
fnp-3528	164	4	laevis	laevis	ADJ
fnp-3528	164	5	oocytes	oocyte	NOUN
fnp-3528	164	6	model	model	VERB
fnp-3528	164	7	in	in	ADP
fnp-3528	164	8	vitro	vitro	X
fnp-3528	164	9	testing	testing	NOUN
fnp-3528	164	10	system,248	system,248	PROPN
fnp-3528	164	11	tsuruoka	tsuruoka	NOUN
fnp-3528	164	12	et	et	PROPN
fnp-3528	164	13	al	al	PROPN
fnp-3528	164	14	.	.	PROPN
fnp-3528	164	15	reported	report	VERB
fnp-3528	164	16	inhibitors	inhibitor	NOUN
fnp-3528	164	17	of	of	ADP
fnp-3528	164	18	this	this	DET
fnp-3528	164	19	transport	transport	NOUN
fnp-3528	164	20	protein.222	protein.222	NOUN
fnp-3528	164	21	while	while	SCONJ
fnp-3528	164	22	digoxin	digoxin	PROPN
fnp-3528	164	23	,	,	PUNCT
fnp-3528	164	24	probenecid	probenecid	PROPN
fnp-3528	164	25	,	,	PUNCT
fnp-3528	164	26	and	and	CCONJ
fnp-3528	164	27	verapamil	verapamil	NOUN
fnp-3528	164	28	(	(	PUNCT
fnp-3528	164	29	all	all	DET
fnp-3528	164	30	figure	figure	VERB
fnp-3528	164	31	 	 	SPACE
fnp-3528	164	32	1	1	NUM
fnp-3528	164	33	)	)	PUNCT
fnp-3528	164	34	could	could	AUX
fnp-3528	164	35	be	be	AUX
fnp-3528	164	36	identified	identify	VERB
fnp-3528	164	37	as	as	ADP
fnp-3528	164	38	very	very	ADV
fnp-3528	164	39	weak	weak	ADJ
fnp-3528	164	40	inhibitors	inhibitor	NOUN
fnp-3528	164	41	of	of	ADP
fnp-3528	164	42	abca8	abca8	PROPN
fnp-3528	164	43	-	-	PUNCT
fnp-3528	164	44	mediated	mediate	VERB
fnp-3528	164	45	estradiol	estradiol	PROPN
fnp-3528	164	46	-	-	PUNCT
fnp-3528	164	47	β	β	NOUN
fnp-3528	164	48	-	-	ADJ
fnp-3528	164	49	glucuronide	glucuronide	ADJ
fnp-3528	164	50	transport	transport	NOUN
fnp-3528	164	51	,	,	PUNCT
fnp-3528	164	52	dofequidar	dofequidar	NOUN
fnp-3528	164	53	(	(	PUNCT
fnp-3528	164	54	ms-209	ms-209	PROPN
fnp-3528	164	55	)	)	PUNCT
fnp-3528	164	56	,	,	PUNCT
fnp-3528	164	57	ochratoxin	ochratoxin	PROPN
fnp-3528	164	58	a	a	X
fnp-3528	164	59	,	,	PUNCT
fnp-3528	164	60	and	and	CCONJ
fnp-3528	164	61	verlukast	verlukast	VERB
fnp-3528	164	62	(	(	PUNCT
fnp-3528	164	63	mk-571	mk-571	ADJ
fnp-3528	164	64	;	;	PUNCT
fnp-3528	164	65	figure	figure	NOUN
fnp-3528	164	66	 	 	SPACE
fnp-3528	164	67	1	1	NUM
fnp-3528	164	68	)	)	PUNCT
fnp-3528	164	69	were	be	AUX
fnp-3528	164	70	discovered	discover	VERB
fnp-3528	164	71	as	as	ADP
fnp-3528	164	72	moderately	moderately	ADV
fnp-3528	164	73	potent	potent	ADJ
fnp-3528	164	74	inhibitors.222	inhibitors.222	ADV
fnp-3528	164	75	in	in	ADP
fnp-3528	164	76	addition	addition	NOUN
fnp-3528	164	77	,	,	PUNCT
fnp-3528	164	78	glibenclamide	glibenclamide	NOUN
fnp-3528	164	79	was	be	AUX
fnp-3528	164	80	also	also	ADV
fnp-3528	164	81	suggested	suggest	VERB
fnp-3528	164	82	to	to	ADP
fnp-3528	164	83	(	(	PUNCT
fnp-3528	164	84	partially	partially	ADV
fnp-3528	164	85	)	)	PUNCT
fnp-3528	164	86	inhibit	inhibit	NOUN
fnp-3528	164	87	abca8	abca8	NOUN
fnp-3528	164	88	function.266	function.266	NOUN
fnp-3528	164	89	activators	activator	NOUN
fnp-3528	164	90	although	although	SCONJ
fnp-3528	164	91	activators	activator	NOUN
fnp-3528	164	92	of	of	ADP
fnp-3528	164	93	abc	abc	PROPN
fnp-3528	164	94	transporters	transporter	NOUN
fnp-3528	164	95	have	have	AUX
fnp-3528	164	96	been	be	AUX
fnp-3528	164	97	reported	report	VERB
fnp-3528	164	98	,	,	PUNCT
fnp-3528	164	99	as	as	ADP
fnp-3528	164	100	for	for	ADP
fnp-3528	164	101	example	example	NOUN
fnp-3528	164	102	,	,	PUNCT
fnp-3528	164	103	for	for	ADP
fnp-3528	164	104	abcb123	abcb123	PROPN
fnp-3528	164	105	and	and	CCONJ
fnp-3528	164	106	abcc	abcc	NOUN
fnp-3528	164	107	transporters,23,283	transporters,23,283	VERB
fnp-3528	164	108	-	-	PUNCT
fnp-3528	164	109	288	288	NUM
fnp-3528	164	110	these	these	DET
fnp-3528	164	111	reports	report	NOUN
fnp-3528	164	112	are	be	AUX
fnp-3528	164	113	somewhat	somewhat	ADV
fnp-3528	164	114	scarce	scarce	ADJ
fnp-3528	164	115	compared	compare	VERB
fnp-3528	164	116	with	with	ADP
fnp-3528	164	117	other	other	ADJ
fnp-3528	164	118	classified	classified	ADJ
fnp-3528	164	119	modulators	modulator	NOUN
fnp-3528	164	120	of	of	ADP
fnp-3528	164	121	abc	abc	PROPN
fnp-3528	164	122	transporters	transporter	NOUN
fnp-3528	164	123	.	.	PUNCT
fnp-3528	165	1	in	in	ADP
fnp-3528	165	2	terms	term	NOUN
fnp-3528	165	3	of	of	ADP
fnp-3528	165	4	a	a	DET
fnp-3528	165	5	subclass	subclass	ADJ
fnp-3528	165	6	abc	abc	PROPN
fnp-3528	165	7	transporters	transporter	NOUN
fnp-3528	165	8	,	,	PUNCT
fnp-3528	165	9	no	no	DET
fnp-3528	165	10	small	small	ADJ
fnp-3528	165	11	-	-	PUNCT
fnp-3528	165	12	molecule	molecule	NOUN
fnp-3528	165	13	activators	activator	NOUN
fnp-3528	165	14	are	be	AUX
fnp-3528	165	15	known	know	VERB
fnp-3528	165	16	.	.	PUNCT
fnp-3528	166	1	however	however	ADV
fnp-3528	166	2	,	,	PUNCT
fnp-3528	166	3	it	it	PRON
fnp-3528	166	4	is	be	AUX
fnp-3528	166	5	well	well	ADV
fnp-3528	166	6	established	establish	VERB
fnp-3528	166	7	and	and	CCONJ
fnp-3528	166	8	has	have	AUX
fnp-3528	166	9	been	be	AUX
fnp-3528	166	10	extensively	extensively	ADV
fnp-3528	166	11	demonstrated	demonstrate	VERB
fnp-3528	166	12	that	that	SCONJ
fnp-3528	166	13	abca1	abca1	NOUN
fnp-3528	166	14	activity	activity	NOUN
fnp-3528	166	15	depends	depend	VERB
fnp-3528	166	16	on	on	ADP
fnp-3528	166	17	(	(	PUNCT
fnp-3528	166	18	co)-administration	co)-administration	NOUN
fnp-3528	166	19	of	of	ADP
fnp-3528	166	20	hdl	hdl	PROPN
fnp-3528	166	21	and/or	and/or	CCONJ
fnp-3528	166	22	apoa1.117	apoa1.117	PROPN
fnp-3528	166	23	hdl	hdl	PROPN
fnp-3528	166	24	and	and	CCONJ
fnp-3528	166	25	apoa1	apoa1	PROPN
fnp-3528	166	26	are	be	AUX
fnp-3528	166	27	not	not	PART
fnp-3528	166	28	small	small	ADJ
fnp-3528	166	29	-	-	PUNCT
fnp-3528	166	30	molecules	molecule	NOUN
fnp-3528	166	31	but	but	CCONJ
fnp-3528	166	32	peptides	peptide	NOUN
fnp-3528	166	33	,	,	PUNCT
fnp-3528	166	34	and	and	CCONJ
fnp-3528	166	35	therefore	therefore	ADV
fnp-3528	166	36	fall	fall	VERB
fnp-3528	166	37	outside	outside	ADV
fnp-3528	166	38	of	of	ADP
fnp-3528	166	39	the	the	DET
fnp-3528	166	40	scope	scope	NOUN
fnp-3528	166	41	of	of	ADP
fnp-3528	166	42	the	the	DET
fnp-3528	166	43	present	present	ADJ
fnp-3528	166	44	review	review	NOUN
fnp-3528	166	45	.	.	PUNCT
fnp-3528	167	1	similarly	similarly	ADV
fnp-3528	167	2	,	,	PUNCT
fnp-3528	167	3	it	it	PRON
fnp-3528	167	4	has	have	AUX
fnp-3528	167	5	been	be	AUX
fnp-3528	167	6	shown	show	VERB
fnp-3528	167	7	in	in	ADP
fnp-3528	167	8	several	several	ADJ
fnp-3528	167	9	reports	report	NOUN
fnp-3528	167	10	that	that	SCONJ
fnp-3528	167	11	hdl	hdl	PROPN
fnp-3528	167	12	-	-	PUNCT
fnp-3528	167	13	mimics	mimics	NOUN
fnp-3528	167	14	consisting	consisting	NOUN
fnp-3528	167	15	of	of	ADP
fnp-3528	167	16	26	26	NUM
fnp-3528	167	17	amino	amino	ADJ
fnp-3528	167	18	acids	acid	NOUN
fnp-3528	167	19	are	be	AUX
fnp-3528	167	20	able	able	ADJ
fnp-3528	167	21	to	to	PART
fnp-3528	167	22	increase	increase	VERB
fnp-3528	167	23	abca1	abca1	NOUN
fnp-3528	167	24	-	-	PUNCT
fnp-3528	167	25	mediated	mediate	VERB
fnp-3528	167	26	transport.289	transport.289	NOUN
fnp-3528	167	27	although	although	SCONJ
fnp-3528	167	28	these	these	DET
fnp-3528	167	29	molecules	molecule	NOUN
fnp-3528	167	30	are	be	AUX
fnp-3528	167	31	also	also	ADV
fnp-3528	167	32	not	not	PART
fnp-3528	167	33	small	small	ADJ
fnp-3528	167	34	-	-	PUNCT
fnp-3528	167	35	molecules	molecule	NOUN
fnp-3528	167	36	,	,	PUNCT
fnp-3528	167	37	the	the	DET
fnp-3528	167	38	scarceness	scarceness	NOUN
fnp-3528	167	39	of	of	ADP
fnp-3528	167	40	activators	activator	NOUN
fnp-3528	167	41	of	of	ADP
fnp-3528	167	42	abca	abca	PROPN
fnp-3528	167	43	transporters	transporter	NOUN
fnp-3528	167	44	warrants	warrant	NOUN
fnp-3528	167	45	the	the	DET
fnp-3528	167	46	inclusion	inclusion	NOUN
fnp-3528	167	47	of	of	ADP
fnp-3528	167	48	these	these	DET
fnp-3528	167	49	middle	middle	ADJ
fnp-3528	167	50	-	-	PUNCT
fnp-3528	167	51	sized	sized	ADJ
fnp-3528	167	52	molecules	molecule	NOUN
fnp-3528	167	53	here	here	ADV
fnp-3528	167	54	.	.	PUNCT
fnp-3528	168	1	in	in	ADP
fnp-3528	168	2	2004	2004	NUM
fnp-3528	168	3	,	,	PUNCT
fnp-3528	168	4	structural	structural	ADJ
fnp-3528	168	5	elements	element	NOUN
fnp-3528	168	6	of	of	ADP
fnp-3528	168	7	apoa1	apoa1	PROPN
fnp-3528	168	8	were	be	AUX
fnp-3528	168	9	discovered	discover	VERB
fnp-3528	168	10	to	to	PART
fnp-3528	168	11	promote	promote	VERB
fnp-3528	168	12	abca1	abca1	NOUN
fnp-3528	168	13	-	-	PUNCT
fnp-3528	168	14	mediated	mediate	VERB
fnp-3528	168	15	cholesterol	cholesterol	NOUN
fnp-3528	168	16	efflux.290	efflux.290	NOUN
fnp-3528	168	17	in	in	ADP
fnp-3528	168	18	2007	2007	NUM
fnp-3528	168	19	,	,	PUNCT
fnp-3528	168	20	vedhachalam	vedhachalam	PROPN
fnp-3528	168	21	et	et	PROPN
fnp-3528	168	22	al	al	PROPN
fnp-3528	168	23	.	.	PROPN
fnp-3528	168	24	discovered	discover	VERB
fnp-3528	168	25	that	that	SCONJ
fnp-3528	168	26	the	the	DET
fnp-3528	168	27	c	c	NOUN
fnp-3528	168	28	-	-	PUNCT
fnp-3528	168	29	terminus	terminus	NOUN
fnp-3528	168	30	of	of	ADP
fnp-3528	168	31	apoe	apoe	NOUN
fnp-3528	168	32	promoted	promote	VERB
fnp-3528	168	33	abca1	abca1	NOUN
fnp-3528	168	34	-	-	PUNCT
fnp-3528	168	35	mediated	mediate	VERB
fnp-3528	168	36	efflux	efflux	NOUN
fnp-3528	168	37	from	from	ADP
fnp-3528	168	38	murine	murine	ADJ
fnp-3528	168	39	j774.a1	j774.a1	PROPN
fnp-3528	168	40	macrophages.291	macrophages.291	NOUN
fnp-3528	168	41	the	the	DET
fnp-3528	168	42	latter	latter	ADJ
fnp-3528	168	43	discovery	discovery	NOUN
fnp-3528	168	44	led	lead	VERB
fnp-3528	168	45	to	to	ADP
fnp-3528	168	46	the	the	DET
fnp-3528	168	47	development	development	NOUN
fnp-3528	168	48	of	of	ADP
fnp-3528	168	49	two	two	NUM
fnp-3528	168	50	short	short	ADJ
fnp-3528	168	51	-	-	PUNCT
fnp-3528	168	52	length	length	NOUN
fnp-3528	168	53	peptides	peptide	NOUN
fnp-3528	168	54	,	,	PUNCT
fnp-3528	168	55	ati-5261	ati-5261	NOUN
fnp-3528	168	56	and	and	CCONJ
fnp-3528	168	57	cs-6253	cs-6253	ADJ
fnp-3528	168	58	,	,	PUNCT
fnp-3528	168	59	consisting	consist	VERB
fnp-3528	168	60	of	of	ADP
fnp-3528	168	61	26	26	NUM
fnp-3528	168	62	amino	amino	NOUN
fnp-3528	168	63	acids	acid	NOUN
fnp-3528	168	64	each.289	each.289	NOUN
fnp-3528	168	65	their	their	PRON
fnp-3528	168	66	amino	amino	NOUN
fnp-3528	168	67	acid	acid	NOUN
fnp-3528	168	68	sequences	sequence	NOUN
fnp-3528	168	69	expressed	express	VERB
fnp-3528	168	70	in	in	ADP
fnp-3528	168	71	single	single	ADJ
fnp-3528	168	72	-	-	PUNCT
fnp-3528	168	73	letter	letter	NOUN
fnp-3528	168	74	code	code	NOUN
fnp-3528	168	75	are	be	AUX
fnp-3528	168	76	evrskleewfaafrefaeeflarlks289	evrskleewfaafrefaeeflarlks289	ADJ
fnp-3528	168	77	and	and	CCONJ
fnp-3528	168	78	evcitskleewlaalcitelaeellacit	evcitskleewlaalcitelaeellacit	PROPN
fnp-3528	168	79	-	-	PUNCT
fnp-3528	168	80	lks	lks	PROPN
fnp-3528	168	81	(	(	PUNCT
fnp-3528	168	82	cit	cit	PROPN
fnp-3528	168	83	=	=	PROPN
fnp-3528	168	84	citrulline),292	citrulline),292	NOUN
fnp-3528	168	85	respectively	respectively	ADV
fnp-3528	168	86	,	,	PUNCT
fnp-3528	168	87	which	which	PRON
fnp-3528	168	88	is	be	AUX
fnp-3528	168	89	of	of	ADP
fnp-3528	168	90	particular	particular	ADJ
fnp-3528	168	91	interest	interest	NOUN
fnp-3528	168	92	for	for	ADP
fnp-3528	168	93	the	the	DET
fnp-3528	168	94	development	development	NOUN
fnp-3528	168	95	of	of	ADP
fnp-3528	168	96	novel	novel	ADJ
fnp-3528	168	97	lead	lead	NOUN
fnp-3528	168	98	structures	structure	NOUN
fnp-3528	168	99	.	.	PUNCT
fnp-3528	169	1	both	both	DET
fnp-3528	169	2	peptides	peptide	NOUN
fnp-3528	169	3	increased	increase	VERB
fnp-3528	169	4	abca1	abca1	NOUN
fnp-3528	169	5	-	-	PUNCT
fnp-3528	169	6	mediated	mediate	VERB
fnp-3528	169	7	cholesterol	cholesterol	NOUN
fnp-3528	169	8	and	and	CCONJ
fnp-3528	169	9	phospholipid	phospholipid	NOUN
fnp-3528	169	10	transport	transport	NOUN
fnp-3528	169	11	in	in	ADP
fnp-3528	169	12	murine	murine	ADJ
fnp-3528	169	13	and	and	CCONJ
fnp-3528	169	14	human	human	ADJ
fnp-3528	169	15	macrophages.289,292	macrophages.289,292	NOUN
fnp-3528	169	16	interestingly	interestingly	ADV
fnp-3528	169	17	,	,	PUNCT
fnp-3528	169	18	cs-6253	cs-6253	PROPN
fnp-3528	169	19	decreased	decrease	VERB
fnp-3528	169	20	125i	125i	NOUN
fnp-3528	169	21	-	-	PUNCT
fnp-3528	169	22	labed	labe	VERB
fnp-3528	169	23	apoa1	apoa1	NOUN
fnp-3528	169	24	binding	bind	VERB
fnp-3528	169	25	to	to	ADP
fnp-3528	169	26	abca1,292	abca1,292	PROPN
fnp-3528	169	27	as	as	SCONJ
fnp-3528	169	28	demonstrated	demonstrate	VERB
fnp-3528	169	29	for	for	ADP
fnp-3528	169	30	glibenclamide,267,270	glibenclamide,267,270	PROPN
fnp-3528	169	31	probucol,246,278	probucol,246,278	NOUN
fnp-3528	169	32	cyclosporine	cyclosporine	VERB
fnp-3528	169	33	a,245,249	a,245,249	NOUN
fnp-3528	169	34	and	and	CCONJ
fnp-3528	169	35	blt-4270	blt-4270	VERB
fnp-3528	169	36	before	before	ADV
fnp-3528	169	37	.	.	PUNCT
fnp-3528	170	1	however	however	ADV
fnp-3528	170	2	,	,	PUNCT
fnp-3528	170	3	cs-6253	cs-6253	PROPN
fnp-3528	170	4	was	be	AUX
fnp-3528	170	5	shown	show	VERB
fnp-3528	170	6	to	to	PART
fnp-3528	170	7	compete	compete	VERB
fnp-3528	170	8	with	with	ADP
fnp-3528	170	9	apoa1	apoa1	PROPN
fnp-3528	170	10	to	to	PART
fnp-3528	170	11	promote	promote	VERB
fnp-3528	170	12	abca1	abca1	NOUN
fnp-3528	170	13	-	-	PUNCT
fnp-3528	170	14	mediated	mediate	VERB
fnp-3528	170	15	transport.292	transport.292	NOUN
fnp-3528	170	16	both	both	PRON
fnp-3528	170	17	ati-5261	ati-5261	NOUN
fnp-3528	170	18	and	and	CCONJ
fnp-3528	170	19	cs-6253	cs-6253	PROPN
fnp-3528	170	20	have	have	VERB
fnp-3528	170	21	a	a	DET
fnp-3528	170	22	high	high	ADJ
fnp-3528	170	23	practical	practical	ADJ
fnp-3528	170	24	relevance	relevance	NOUN
fnp-3528	170	25	regarding	regard	VERB
fnp-3528	170	26	ad	ad	NOUN
fnp-3528	170	27	and	and	CCONJ
fnp-3528	170	28	other	other	ADJ
fnp-3528	170	29	neurodegenerative	neurodegenerative	ADJ
fnp-3528	170	30	diseases	disease	NOUN
fnp-3528	170	31	,	,	PUNCT
fnp-3528	170	32	as	as	SCONJ
fnp-3528	170	33	these	these	DET
fnp-3528	170	34	agents	agent	NOUN
fnp-3528	170	35	demonstrated	demonstrate	VERB
fnp-3528	170	36	in	in	ADP
fnp-3528	170	37	vivo	vivo	ADJ
fnp-3528	170	38	efficacy.289,293	efficacy.289,293	NOUN
fnp-3528	170	39	ati-5261	ati-5261	NOUN
fnp-3528	170	40	treatment	treatment	NOUN
fnp-3528	170	41	of	of	ADP
fnp-3528	170	42	high	high	ADJ
fnp-3528	170	43	fat	fat	ADJ
fnp-3528	170	44	diet	diet	NOUN
fnp-3528	170	45	-	-	PUNCT
fnp-3528	170	46	fed	feed	VERB
fnp-3528	170	47	apoe	apoe	ADJ
fnp-3528	170	48	knock	knock	NOUN
fnp-3528	170	49	-	-	PUNCT
fnp-3528	170	50	out	out	ADP
fnp-3528	170	51	mice	mouse	NOUN
fnp-3528	170	52	decreased	decrease	VERB
fnp-3528	170	53	cholesterol	cholesterol	NOUN
fnp-3528	170	54	levels	level	NOUN
fnp-3528	170	55	in	in	ADP
fnp-3528	170	56	both	both	DET
fnp-3528	170	57	plasma	plasma	NOUN
fnp-3528	170	58	and	and	CCONJ
fnp-3528	170	59	feces	fece	NOUN
fnp-3528	170	60	and	and	CCONJ
fnp-3528	170	61	reduced	reduce	VERB
fnp-3528	170	62	atherosclerotic	atherosclerotic	ADJ
fnp-3528	170	63	lesions.289	lesions.289	ADJ
fnp-3528	170	64	for	for	ADP
fnp-3528	170	65	cs-6253	cs-6253	ADJ
fnp-3528	170	66	,	,	PUNCT
fnp-3528	170	67	a	a	DET
fnp-3528	170	68	reduction	reduction	NOUN
fnp-3528	170	69	of	of	ADP
fnp-3528	170	70	aβ42	aβ42	PROPN
fnp-3528	170	71	levels	level	NOUN
fnp-3528	170	72	and	and	CCONJ
fnp-3528	170	73	tau	tau	PROPN
fnp-3528	170	74	protein	protein	NOUN
fnp-3528	170	75	phosphorylation	phosphorylation	NOUN
fnp-3528	170	76	in	in	ADP
fnp-3528	170	77	transgenic	transgenic	NOUN
fnp-3528	170	78	humanized	humanize	VERB
fnp-3528	170	79	apoe4	apoe4	ADJ
fnp-3528	170	80	mice	mouse	NOUN
fnp-3528	170	81	was	be	AUX
fnp-3528	170	82	demonstrated	demonstrate	VERB
fnp-3528	170	83	,	,	PUNCT
fnp-3528	170	84	which	which	PRON
fnp-3528	170	85	was	be	AUX
fnp-3528	170	86	accompanied	accompany	VERB
fnp-3528	170	87	by	by	ADP
fnp-3528	170	88	improved	improved	ADJ
fnp-3528	170	89	cognitive	cognitive	ADJ
fnp-3528	170	90	functions.293	functions.293	NOUN
fnp-3528	170	91	interestingly	interestingly	ADV
fnp-3528	170	92	,	,	PUNCT
fnp-3528	170	93	an	an	DET
fnp-3528	170	94	elevation	elevation	NOUN
fnp-3528	170	95	of	of	ADP
fnp-3528	170	96	abca1	abca1	NOUN
fnp-3528	170	97	protein	protein	NOUN
fnp-3528	170	98	was	be	AUX
fnp-3528	170	99	also	also	ADV
fnp-3528	170	100	observed	observe	VERB
fnp-3528	170	101	in	in	ADP
fnp-3528	170	102	treated	treat	VERB
fnp-3528	170	103	mice.293	mice.293	NOUN
fnp-3528	170	104	indeed	indeed	ADV
fnp-3528	170	105	,	,	PUNCT
fnp-3528	170	106	a	a	DET
fnp-3528	170	107	stabilization	stabilization	NOUN
fnp-3528	170	108	and/or	and/or	CCONJ
fnp-3528	170	109	induction	induction	NOUN
fnp-3528	170	110	may	may	AUX
fnp-3528	170	111	also	also	ADV
fnp-3528	170	112	have	have	AUX
fnp-3528	170	113	contributed	contribute	VERB
fnp-3528	170	114	to	to	ADP
fnp-3528	170	115	the	the	DET
fnp-3528	170	116	observed	observed	ADJ
fnp-3528	170	117	effects	effect	NOUN
fnp-3528	170	118	.	.	PUNCT
fnp-3528	171	1	however	however	ADV
fnp-3528	171	2	,	,	PUNCT
fnp-3528	171	3	the	the	DET
fnp-3528	171	4	proven	prove	VERB
fnp-3528	171	5	direct	direct	ADJ
fnp-3528	171	6	binding	binding	NOUN
fnp-3528	171	7	of	of	ADP
fnp-3528	171	8	these	these	DET
fnp-3528	171	9	agents	agent	NOUN
fnp-3528	171	10	suggested	suggest	VERB
fnp-3528	171	11	that	that	SCONJ
fnp-3528	171	12	activation	activation	NOUN
fnp-3528	171	13	takes	take	VERB
fnp-3528	171	14	place	place	NOUN
fnp-3528	171	15	as	as	ADP
fnp-3528	171	16	the	the	DET
fnp-3528	171	17	major	major	ADJ
fnp-3528	171	18	mode	mode	NOUN
fnp-3528	171	19	of	of	ADP
fnp-3528	171	20	action	action	NOUN
fnp-3528	171	21	.	.	PUNCT
fnp-3528	172	1	nonetheless	nonetheless	ADV
fnp-3528	172	2	,	,	PUNCT
fnp-3528	172	3	cs-6253	cs-6253	PROPN
fnp-3528	172	4	has	have	AUX
fnp-3528	172	5	not	not	PART
fnp-3528	172	6	been	be	AUX
fnp-3528	172	7	tested	test	VERB
fnp-3528	172	8	in	in	ADP
fnp-3528	172	9	ad	ad	NOUN
fnp-3528	172	10	mouse	mouse	NOUN
fnp-3528	172	11	models	model	NOUN
fnp-3528	172	12	so	so	ADV
fnp-3528	172	13	far	far	ADV
fnp-3528	172	14	,	,	PUNCT
fnp-3528	172	15	and	and	CCONJ
fnp-3528	172	16	being	be	AUX
fnp-3528	172	17	a	a	DET
fnp-3528	172	18	peptide	peptide	NOUN
fnp-3528	172	19	,	,	PUNCT
fnp-3528	172	20	it	it	PRON
fnp-3528	172	21	would	would	AUX
fnp-3528	172	22	not	not	PART
fnp-3528	172	23	be	be	AUX
fnp-3528	172	24	suitable	suitable	ADJ
fnp-3528	172	25	for	for	ADP
fnp-3528	172	26	oral	oral	ADJ
fnp-3528	172	27	application	application	NOUN
fnp-3528	172	28	in	in	ADP
fnp-3528	172	29	patients	patient	NOUN
fnp-3528	172	30	.	.	PUNCT
fnp-3528	173	1	small	small	ADJ
fnp-3528	173	2	-	-	PUNCT
fnp-3528	173	3	molecule	molecule	NOUN
fnp-3528	173	4	regulators	regulator	NOUN
fnp-3528	173	5	of	of	ADP
fnp-3528	173	6	abca	abca	PROPN
fnp-3528	173	7	transporters	transporter	NOUN
fnp-3528	173	8	the	the	DET
fnp-3528	173	9	herein	herein	NOUN
fnp-3528	173	10	discussed	discuss	VERB
fnp-3528	173	11	regulators	regulator	NOUN
fnp-3528	173	12	interfere	interfere	VERB
fnp-3528	173	13	with	with	ADP
fnp-3528	173	14	abca	abca	NOUN
fnp-3528	173	15	transporter	transporter	NOUN
fnp-3528	173	16	expression	expression	NOUN
fnp-3528	173	17	and/or	and/or	CCONJ
fnp-3528	173	18	trafficking	traffic	VERB
fnp-3528	173	19	.	.	PUNCT
fnp-3528	174	1	important	important	ADJ
fnp-3528	174	2	representatives	representative	NOUN
fnp-3528	174	3	are	be	AUX
fnp-3528	174	4	depicted	depict	VERB
fnp-3528	174	5	in	in	ADP
fnp-3528	174	6	figure	figure	NOUN
fnp-3528	174	7	 	 	SPACE
fnp-3528	174	8	2	2	NUM
fnp-3528	174	9	and	and	CCONJ
fnp-3528	174	10	additional	additional	ADJ
fnp-3528	174	11	information	information	NOUN
fnp-3528	174	12	is	be	AUX
fnp-3528	174	13	given	give	VERB
fnp-3528	174	14	in	in	ADP
fnp-3528	174	15	terms	term	NOUN
fnp-3528	174	16	of	of	ADP
fnp-3528	174	17	their	their	PRON
fnp-3528	174	18	mode	mode	NOUN
fnp-3528	174	19	of	of	ADP
fnp-3528	174	20	modulation	modulation	NOUN
fnp-3528	174	21	.	.	PUNCT
fnp-3528	175	1	since	since	SCONJ
fnp-3528	175	2	many	many	ADJ
fnp-3528	175	3	different	different	ADJ
fnp-3528	175	4	pathways	pathway	NOUN
fnp-3528	175	5	are	be	AUX
fnp-3528	175	6	involved	involve	VERB
fnp-3528	175	7	in	in	ADP
fnp-3528	175	8	abca	abca	PROPN
fnp-3528	175	9	transporter	transporter	NOUN
fnp-3528	175	10	regulation	regulation	NOUN
fnp-3528	175	11	,	,	PUNCT
fnp-3528	175	12	figure	figure	NOUN
fnp-3528	175	13	3	3	NUM
fnp-3528	175	14	provides	provide	VERB
fnp-3528	175	15	a	a	DET
fnp-3528	175	16	general	general	ADJ
fnp-3528	175	17	overview	overview	NOUN
fnp-3528	175	18	of	of	ADP
fnp-3528	175	19	participating	participate	VERB
fnp-3528	175	20	proteins	protein	NOUN
fnp-3528	175	21	and	and	CCONJ
fnp-3528	175	22	protein	protein	NOUN
fnp-3528	175	23	families	family	NOUN
fnp-3528	175	24	in	in	ADP
fnp-3528	175	25	terms	term	NOUN
fnp-3528	175	26	of	of	ADP
fnp-3528	175	27	the	the	DET
fnp-3528	175	28	most	most	ADV
fnp-3528	175	29	studied	study	VERB
fnp-3528	175	30	abca	abca	NOUN
fnp-3528	175	31	transporter	transporter	NOUN
fnp-3528	175	32	,	,	PUNCT
fnp-3528	175	33	abca1	abca1	NOUN
fnp-3528	175	34	.	.	PUNCT
fnp-3528	176	1	inducers	inducer	NOUN
fnp-3528	176	2	abca1	abca1	PROPN
fnp-3528	176	3	lxr	lxr	PROPN
fnp-3528	176	4	and	and	CCONJ
fnp-3528	176	5	rxr	rxr	PROPN
fnp-3528	176	6	pathways	pathway	NOUN
fnp-3528	176	7	given	give	VERB
fnp-3528	176	8	the	the	DET
fnp-3528	176	9	findings	finding	NOUN
fnp-3528	176	10	in	in	ADP
fnp-3528	176	11	ad	ad	NOUN
fnp-3528	176	12	mouse	mouse	NOUN
fnp-3528	176	13	models	model	NOUN
fnp-3528	176	14	with	with	ADP
fnp-3528	176	15	knock	knock	NOUN
fnp-3528	176	16	-	-	PUNCT
fnp-3528	176	17	out	out	NOUN
fnp-3528	176	18	of	of	ADP
fnp-3528	176	19	abca1	abca1	NOUN
fnp-3528	176	20	/	/	SYM
fnp-3528	176	21	abca1	abca1	NOUN
fnp-3528	176	22	or	or	CCONJ
fnp-3528	176	23	overexpression	overexpression	NOUN
fnp-3528	176	24	of	of	ADP
fnp-3528	176	25	abca1	abca1	NOUN
fnp-3528	176	26	,	,	PUNCT
fnp-3528	176	27	upregulating	upregulating	ADJ
fnp-3528	176	28	abca1	abca1	NOUN
fnp-3528	176	29	activity	activity	NOUN
fnp-3528	176	30	may	may	AUX
fnp-3528	176	31	be	be	AUX
fnp-3528	176	32	a	a	DET
fnp-3528	176	33	therapeutic	therapeutic	ADJ
fnp-3528	176	34	strategy	strategy	NOUN
fnp-3528	176	35	for	for	ADP
fnp-3528	176	36	decreasing	decrease	VERB
fnp-3528	176	37	aβ	aβ	DET
fnp-3528	176	38	pathology	pathology	NOUN
fnp-3528	176	39	in	in	ADP
fnp-3528	176	40	ad	ad	NOUN
fnp-3528	176	41	.	.	PUNCT
fnp-3528	177	1	abca1	abca1	PROPN
fnp-3528	177	2	is	be	AUX
fnp-3528	177	3	under	under	ADP
fnp-3528	177	4	the	the	DET
fnp-3528	177	5	transcriptional	transcriptional	ADJ
fnp-3528	177	6	control	control	NOUN
fnp-3528	177	7	of	of	ADP
fnp-3528	177	8	the	the	DET
fnp-3528	177	9	nuclear	nuclear	ADJ
fnp-3528	177	10	receptors	receptor	NOUN
fnp-3528	177	11	liver	liver	NOUN
fnp-3528	177	12	-	-	PUNCT
fnp-3528	177	13	x	x	NOUN
fnp-3528	177	14	-	-	NOUN
fnp-3528	177	15	receptor	receptor	NOUN
fnp-3528	177	16	(	(	PUNCT
fnp-3528	177	17	lxr	lxr	PROPN
fnp-3528	177	18	)	)	PUNCT
fnp-3528	177	19	and	and	CCONJ
fnp-3528	177	20	retinoid	retinoid	NOUN
fnp-3528	177	21	-	-	PUNCT
fnp-3528	177	22	x	x	NOUN
fnp-3528	177	23	-	-	NOUN
fnp-3528	177	24	receptor	receptor	NOUN
fnp-3528	177	25	(	(	PUNCT
fnp-3528	177	26	rxr),294	rxr),294	NOUN
fnp-3528	177	27	-	-	NUM
fnp-3528	177	28	296	296	NUM
fnp-3528	177	29	which	which	PRON
fnp-3528	177	30	can	can	AUX
fnp-3528	177	31	be	be	AUX
fnp-3528	177	32	targeted	target	VERB
fnp-3528	177	33	by	by	ADP
fnp-3528	177	34	small	small	ADJ
fnp-3528	177	35	-	-	PUNCT
fnp-3528	177	36	molecule	molecule	NOUN
fnp-3528	177	37	agonists	agonist	NOUN
fnp-3528	177	38	of	of	ADP
fnp-3528	177	39	lxr	lxr	PROPN
fnp-3528	177	40	and	and	CCONJ
fnp-3528	177	41	rxr	rxr	NOUN
fnp-3528	177	42	to	to	PART
fnp-3528	177	43	induce	induce	VERB
fnp-3528	177	44	abca1	abca1	NOUN
fnp-3528	177	45	expression	expression	NOUN
fnp-3528	177	46	(	(	PUNCT
fnp-3528	177	47	figure	figure	NOUN
fnp-3528	177	48	 	 	SPACE
fnp-3528	177	49	3	3	NUM
fnp-3528	177	50	)	)	PUNCT
fnp-3528	177	51	.	.	PUNCT
fnp-3528	178	1	numerous	numerous	ADJ
fnp-3528	178	2	studies	study	NOUN
fnp-3528	178	3	reported	report	VERB
fnp-3528	178	4	that	that	SCONJ
fnp-3528	178	5	treatment	treatment	NOUN
fnp-3528	178	6	of	of	ADP
fnp-3528	178	7	app	app	ADJ
fnp-3528	178	8	-	-	PUNCT
fnp-3528	178	9	transgenic	transgenic	NOUN
fnp-3528	178	10	mice	mouse	NOUN
fnp-3528	178	11	with	with	ADP
fnp-3528	178	12	lxr	lxr	PROPN
fnp-3528	178	13	or	or	CCONJ
fnp-3528	178	14	rxr	rxr	PROPN
fnp-3528	178	15	agonists	agonist	NOUN
fnp-3528	178	16	decreased	decrease	VERB
fnp-3528	178	17	aβ	aβ	PRON
fnp-3528	178	18	load126,297	load126,297	PROPN
fnp-3528	178	19	-	-	PUNCT
fnp-3528	178	20	301	301	NUM
fnp-3528	178	21	and/or	and/or	CCONJ
fnp-3528	178	22	improved	improve	VERB
fnp-3528	178	23	cognitive	cognitive	ADJ
fnp-3528	178	24	impairment.126,297,298,300	impairment.126,297,298,300	PROPN
fnp-3528	178	25	other	other	ADJ
fnp-3528	178	26	studies	study	NOUN
fnp-3528	178	27	reported	report	VERB
fnp-3528	178	28	cognitive	cognitive	ADJ
fnp-3528	178	29	improvement	improvement	NOUN
fnp-3528	178	30	without	without	ADP
fnp-3528	178	31	significant	significant	ADJ
fnp-3528	178	32	changes	change	NOUN
fnp-3528	178	33	in	in	ADP
fnp-3528	178	34	aβ	aβ	ADP
fnp-3528	178	35	load	load	NOUN
fnp-3528	178	36	in	in	ADP
fnp-3528	178	37	app	app	ADJ
fnp-3528	178	38	-	-	PUNCT
fnp-3528	178	39	transgenic	transgenic	ADJ
fnp-3528	178	40	mice	mouse	NOUN
fnp-3528	178	41	treated	treat	VERB
fnp-3528	178	42	with	with	ADP
fnp-3528	178	43	lxr	lxr	PROPN
fnp-3528	178	44	agonists.302,303	agonists.302,303	PUNCT
fnp-3528	178	45	lxr	lxr	NOUN
fnp-3528	178	46	and	and	CCONJ
fnp-3528	178	47	rxr	rxr	PROPN
fnp-3528	178	48	agonists	agonist	NOUN
fnp-3528	178	49	have	have	AUX
fnp-3528	178	50	already	already	ADV
fnp-3528	178	51	been	be	AUX
fnp-3528	178	52	described	describe	VERB
fnp-3528	178	53	extensively	extensively	ADV
fnp-3528	178	54	as	as	ADP
fnp-3528	178	55	potential	potential	ADJ
fnp-3528	178	56	therapeutics	therapeutic	NOUN
fnp-3528	178	57	in	in	ADP
fnp-3528	178	58	the	the	DET
fnp-3528	178	59	literature	literature	NOUN
fnp-3528	178	60	,	,	PUNCT
fnp-3528	178	61	also	also	ADV
fnp-3528	178	62	with	with	ADP
fnp-3528	178	63	respect	respect	NOUN
fnp-3528	178	64	to	to	ADP
fnp-3528	178	65	ad.304	ad.304	PROPN
fnp-3528	178	66	the	the	DET
fnp-3528	178	67	present	present	ADJ
fnp-3528	178	68	review	review	NOUN
fnp-3528	178	69	will	will	AUX
fnp-3528	178	70	focus	focus	VERB
fnp-3528	178	71	on	on	ADP
fnp-3528	178	72	those	those	DET
fnp-3528	178	73	agonists	agonist	NOUN
fnp-3528	178	74	that	that	PRON
fnp-3528	178	75	were	be	AUX
fnp-3528	178	76	reported	report	VERB
fnp-3528	178	77	in	in	ADP
fnp-3528	178	78	clear	clear	ADJ
fnp-3528	178	79	association	association	NOUN
fnp-3528	178	80	with	with	ADP
fnp-3528	178	81	abca1	abca1	PROPN
fnp-3528	178	82	.	.	PUNCT
fnp-3528	179	1	oxysterols	oxysterol	NOUN
fnp-3528	179	2	and	and	CCONJ
fnp-3528	179	3	retinoic	retinoic	ADJ
fnp-3528	179	4	acids	acid	NOUN
fnp-3528	179	5	22-(r)-hydroxycholesterol	22-(r)-hydroxycholesterol	PROPN
fnp-3528	179	6	(	(	PUNCT
fnp-3528	179	7	figure	figure	NOUN
fnp-3528	179	8	 	 	SPACE
fnp-3528	179	9	2	2	NUM
fnp-3528	179	10	)	)	PUNCT
fnp-3528	179	11	has	have	AUX
fnp-3528	179	12	been	be	AUX
fnp-3528	179	13	established	establish	VERB
fnp-3528	179	14	as	as	ADP
fnp-3528	179	15	the	the	DET
fnp-3528	179	16	natural	natural	ADJ
fnp-3528	179	17	gold	gold	ADJ
fnp-3528	179	18	standard	standard	NOUN
fnp-3528	179	19	for	for	ADP
fnp-3528	179	20	abca1	abca1	NOUN
fnp-3528	179	21	/	/	SYM
fnp-3528	179	22	abca1	abca1	NOUN
fnp-3528	179	23	induction	induction	NOUN
fnp-3528	179	24	through	through	ADP
fnp-3528	179	25	lxr	lxr	PROPN
fnp-3528	179	26	activation,122,205,249,252,259,262	activation,122,205,249,252,259,262	PROPN
fnp-3528	179	27	-	-	PUNCT
fnp-3528	179	28	264,268,277,278,305	264,268,277,278,305	NUM
fnp-3528	179	29	-	-	PUNCT
fnp-3528	179	30	315	315	NUM
fnp-3528	179	31	while	while	SCONJ
fnp-3528	179	32	9	9	NUM
fnp-3528	179	33	-	-	PUNCT
fnp-3528	179	34	cis	cis	NOUN
fnp-3528	179	35	retinoic	retinoic	NOUN
fnp-3528	179	36	acid	acid	NOUN
fnp-3528	179	37	(	(	PUNCT
fnp-3528	179	38	figure	figure	NOUN
fnp-3528	179	39	 	 	SPACE
fnp-3528	179	40	2	2	NUM
fnp-3528	179	41	)	)	PUNCT
fnp-3528	179	42	became	become	VERB
fnp-3528	179	43	the	the	DET
fnp-3528	179	44	natural	natural	ADJ
fnp-3528	179	45	gold	gold	ADJ
fnp-3528	179	46	standard	standard	NOUN
fnp-3528	179	47	for	for	ADP
fnp-3528	179	48	rxr	rxr	PROPN
fnp-3528	179	49	activation.122,245,249,259,262,264,277,278,309,311,313,316	activation.122,245,249,259,262,264,277,278,309,311,313,316	PROPN
fnp-3528	179	50	the	the	DET
fnp-3528	179	51	inducing	inducing	ADJ
fnp-3528	179	52	effects	effect	NOUN
fnp-3528	179	53	were	be	AUX
fnp-3528	179	54	described	describe	VERB
fnp-3528	179	55	both	both	CCONJ
fnp-3528	179	56	on	on	ADP
fnp-3528	179	57	abca1	abca1	NOUN
fnp-3528	179	58	/	/	SYM
fnp-3528	179	59	abca1	abca1	NOUN
fnp-3528	179	60	mrna122,205,252,263,264,305,307	mrna122,205,252,263,264,305,307	NOUN
fnp-3528	179	61	-	-	PUNCT
fnp-3528	179	62	311,313,315	311,313,315	NUM
fnp-3528	179	63	-	-	PUNCT
fnp-3528	179	64	317	317	NUM
fnp-3528	179	65	and	and	CCONJ
fnp-3528	179	66	abca1	abca1	NOUN
fnp-3528	179	67	protein	protein	NOUN
fnp-3528	179	68	levels.122,252,263,264,306,309	levels.122,252,263,264,306,309	NOUN
fnp-3528	179	69	-	-	PUNCT
fnp-3528	179	70	311,316,318	311,316,318	NUM
fnp-3528	179	71	other	other	ADJ
fnp-3528	179	72	oxysterols	oxysterol	NOUN
fnp-3528	179	73	like	like	ADP
fnp-3528	179	74	4	4	NUM
fnp-3528	179	75	-	-	PUNCT
fnp-3528	179	76	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	179	77	,	,	PUNCT
fnp-3528	179	78	20-(s)-hydroxycholesterol	20-(s)-hydroxycholesterol	NUM
fnp-3528	179	79	,	,	PUNCT
fnp-3528	179	80	22-(s)-hydroxycholesterol	22-(s)-hydroxycholesterol	NUM
fnp-3528	179	81	,	,	PUNCT
fnp-3528	179	82	24	24	NUM
fnp-3528	179	83	-	-	PUNCT
fnp-3528	179	84	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	179	85	,	,	PUNCT
fnp-3528	179	86	24-(s)-hydroxycholesterol	24-(s)-hydroxycholesterol	NUM
fnp-3528	179	87	,	,	PUNCT
fnp-3528	179	88	25	25	NUM
fnp-3528	179	89	-	-	PUNCT
fnp-3528	179	90	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	179	91	,	,	PUNCT
fnp-3528	179	92	27	27	NUM
fnp-3528	179	93	-	-	PUNCT
fnp-3528	179	94	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	179	95	,	,	PUNCT
fnp-3528	179	96	and	and	CCONJ
fnp-3528	179	97	cholesterol	cholesterol	NOUN
fnp-3528	179	98	itself	itself	PRON
fnp-3528	179	99	also	also	ADV
fnp-3528	179	100	induced	induce	VERB
fnp-3528	179	101	abca1	abca1	NOUN
fnp-3528	179	102	/	/	SYM
fnp-3528	179	103	abca1	abca1	NOUN
fnp-3528	180	1	mrna205,305,313,315,319	mrna205,305,313,315,319	PROPN
fnp-3528	180	2	-	-	PUNCT
fnp-3528	180	3	327	327	NUM
fnp-3528	180	4	and	and	CCONJ
fnp-3528	180	5	abca1	abca1	NOUN
fnp-3528	180	6	protein	protein	NOUN
fnp-3528	180	7	levels.321,328	levels.321,328	VERB
fnp-3528	180	8	the	the	DET
fnp-3528	180	9	increase	increase	NOUN
fnp-3528	180	10	in	in	ADP
fnp-3528	180	11	abca1	abca1	NOUN
fnp-3528	180	12	protein	protein	NOUN
fnp-3528	180	13	was	be	AUX
fnp-3528	180	14	functionally	functionally	ADV
fnp-3528	180	15	confirmed	confirm	VERB
fnp-3528	180	16	by	by	ADP
fnp-3528	180	17	an	an	DET
fnp-3528	180	18	enhanced	enhanced	ADJ
fnp-3528	180	19	cholesterol305,306,313,315,318	cholesterol305,306,313,315,318	PROPN
fnp-3528	180	20	and	and	CCONJ
fnp-3528	180	21	phospholipid	phospholipid	NOUN
fnp-3528	180	22	efflux,311,318	efflux,311,318	ADV
fnp-3528	180	23	as	as	ADV
fnp-3528	180	24	well	well	ADV
fnp-3528	180	25	as	as	ADP
fnp-3528	180	26	reduced	reduce	VERB
fnp-3528	180	27	total	total	ADJ
fnp-3528	180	28	cholesterol	cholesterol	NOUN
fnp-3528	180	29	influx.305	influx.305	NOUN
fnp-3528	180	30	specifically	specifically	ADV
fnp-3528	180	31	22-(r)-hydroxycholesterol	22-(r)-hydroxycholesterol	NUM
fnp-3528	180	32	and	and	CCONJ
fnp-3528	180	33	cholesterol	cholesterol	NOUN
fnp-3528	180	34	induced	induce	VERB
fnp-3528	180	35	both	both	CCONJ
fnp-3528	180	36	lxra	lxra	NOUN
fnp-3528	180	37	/	/	SYM
fnp-3528	180	38	lxra	lxra	NOUN
fnp-3528	180	39	and	and	CCONJ
fnp-3528	180	40	lxrb	lxrb	NOUN
fnp-3528	180	41	/	/	SYM
fnp-3528	180	42	lxrb.310,321	lxrb.310,321	PROPN
fnp-3528	180	43	additionally	additionally	ADV
fnp-3528	180	44	,	,	PUNCT
fnp-3528	180	45	cholesterol	cholesterol	NOUN
fnp-3528	180	46	also	also	ADV
fnp-3528	180	47	induced	induce	VERB
fnp-3528	180	48	murine	murine	ADJ
fnp-3528	180	49	peroxisome	peroxisome	NOUN
fnp-3528	180	50	proliferator	proliferator	NOUN
fnp-3528	180	51	-	-	PUNCT
fnp-3528	180	52	activated	activate	VERB
fnp-3528	180	53	receptor	receptor	NOUN
fnp-3528	180	54	γ	γ	X
fnp-3528	180	55	(	(	PUNCT
fnp-3528	180	56	ppar	ppar	NOUN
fnp-3528	180	57	-	-	PUNCT
fnp-3528	180	58	γ	γ	NOUN
fnp-3528	180	59	)	)	PUNCT
fnp-3528	180	60	mrna	mrna	NOUN
fnp-3528	180	61	(	(	PUNCT
fnp-3528	180	62	pparg),321	pparg),321	NOUN
fnp-3528	180	63	which	which	PRON
fnp-3528	180	64	represents	represent	VERB
fnp-3528	180	65	an	an	DET
fnp-3528	180	66	important	important	ADJ
fnp-3528	180	67	alternative	alternative	ADJ
fnp-3528	180	68	pathway	pathway	NOUN
fnp-3528	180	69	for	for	ADP
fnp-3528	180	70	abca1	abca1	NOUN
fnp-3528	180	71	/	/	SYM
fnp-3528	180	72	abca1	abca1	NOUN
fnp-3528	180	73	induction	induction	NOUN
fnp-3528	180	74	.	.	PUNCT
fnp-3528	181	1	furthermore	furthermore	ADV
fnp-3528	181	2	,	,	PUNCT
fnp-3528	181	3	24-(s)-hydroxycholesterol	24-(s)-hydroxycholesterol	NUM
fnp-3528	181	4	reduced	reduce	VERB
fnp-3528	181	5	in	in	ADP
fnp-3528	181	6	parallel	parallel	VERB
fnp-3528	181	7	the	the	DET
fnp-3528	181	8	sterol	sterol	NOUN
fnp-3528	181	9	regulation	regulation	NOUN
fnp-3528	181	10	element	element	NOUN
fnp-3528	181	11	-	-	PUNCT
fnp-3528	181	12	binding	bind	VERB
fnp-3528	181	13	protein	protein	NOUN
fnp-3528	181	14	2	2	NUM
fnp-3528	181	15	(	(	PUNCT
fnp-3528	181	16	srebp2	srebp2	NOUN
fnp-3528	181	17	)	)	PUNCT
fnp-3528	181	18	gene	gene	NOUN
fnp-3528	181	19	expression	expression	NOUN
fnp-3528	181	20	(	(	PUNCT
fnp-3528	181	21	srebp2).323	srebp2).323	VERB
fnp-3528	181	22	the	the	DET
fnp-3528	181	23	sreb	sreb	NOUN
fnp-3528	181	24	protein	protein	NOUN
fnp-3528	181	25	family	family	NOUN
fnp-3528	181	26	also	also	ADV
fnp-3528	181	27	represents	represent	VERB
fnp-3528	181	28	another	another	DET
fnp-3528	181	29	important	important	ADJ
fnp-3528	181	30	pathway	pathway	NOUN
fnp-3528	181	31	in	in	ADP
fnp-3528	181	32	abca1	abca1	NOUN
fnp-3528	181	33	/	/	SYM
fnp-3528	181	34	abca1	abca1	NOUN
fnp-3528	181	35	regulation	regulation	NOUN
fnp-3528	181	36	.	.	PUNCT
fnp-3528	182	1	the	the	DET
fnp-3528	182	2	9	9	NUM
fnp-3528	182	3	-	-	PUNCT
fnp-3528	182	4	cis	cis	NOUN
fnp-3528	182	5	-	-	PUNCT
fnp-3528	182	6	retinoic	retinoic	ADJ
fnp-3528	182	7	acid	acid	NOUN
fnp-3528	182	8	derivative	derivative	NOUN
fnp-3528	182	9	all	all	DET
fnp-3528	182	10	-	-	PUNCT
fnp-3528	182	11	trans¬-retinoic	trans¬-retinoic	NOUN
fnp-3528	182	12	acid	acid	NOUN
fnp-3528	182	13	(	(	PUNCT
fnp-3528	182	14	atra	atra	PROPN
fnp-3528	182	15	)	)	PUNCT
fnp-3528	182	16	significantly	significantly	ADV
fnp-3528	182	17	increased	increase	VERB
fnp-3528	182	18	abca1	abca1	NOUN
fnp-3528	182	19	/	/	SYM
fnp-3528	182	20	abca1	abca1	NOUN
fnp-3528	182	21	mrna	mrna	NOUN
fnp-3528	182	22	and	and	CCONJ
fnp-3528	182	23	abca1	abca1	NOUN
fnp-3528	182	24	protein	protein	NOUN
fnp-3528	182	25	content	content	NOUN
fnp-3528	182	26	in	in	ADP
fnp-3528	182	27	murine	murine	ADJ
fnp-3528	182	28	and	and	CCONJ
fnp-3528	182	29	human	human	ADJ
fnp-3528	182	30	macrophages	macrophage	NOUN
fnp-3528	182	31	,	,	PUNCT
fnp-3528	182	32	which	which	PRON
fnp-3528	182	33	was	be	AUX
fnp-3528	182	34	paralleled	parallel	VERB
fnp-3528	182	35	by	by	ADP
fnp-3528	182	36	increased	increase	VERB
fnp-3528	182	37	lxra	lxra	NOUN
fnp-3528	182	38	mrna	mrna	PROPN
fnp-3528	182	39	levels	level	NOUN
fnp-3528	182	40	in	in	ADP
fnp-3528	182	41	human	human	ADJ
fnp-3528	182	42	macrophages.329	macrophages.329	PROPN
fnp-3528	182	43	this	this	DET
fnp-3528	182	44	increase	increase	NOUN
fnp-3528	182	45	resulted	result	VERB
fnp-3528	182	46	in	in	ADP
fnp-3528	182	47	a	a	DET
fnp-3528	182	48	subsequently	subsequently	ADV
fnp-3528	182	49	enhanced	enhance	VERB
fnp-3528	182	50	cholesterol	cholesterol	NOUN
fnp-3528	182	51	efflux	efflux	NOUN
fnp-3528	182	52	from	from	ADP
fnp-3528	182	53	murine	murine	ADJ
fnp-3528	182	54	macrophages	macrophage	NOUN
fnp-3528	182	55	.	.	PUNCT
fnp-3528	183	1	atra	atra	PROPN
fnp-3528	183	2	is	be	AUX
fnp-3528	183	3	an	an	DET
fnp-3528	183	4	agonist	agonist	NOUN
fnp-3528	183	5	of	of	ADP
fnp-3528	183	6	the	the	DET
fnp-3528	183	7	retinoic	retinoic	ADJ
fnp-3528	183	8	acid	acid	NOUN
fnp-3528	183	9	receptor	receptor	NOUN
fnp-3528	183	10	(	(	PUNCT
fnp-3528	183	11	rar),329	rar),329	VERB
fnp-3528	183	12	which	which	PRON
fnp-3528	183	13	is	be	AUX
fnp-3528	183	14	in	in	ADP
fnp-3528	183	15	close	close	ADJ
fnp-3528	183	16	relation	relation	NOUN
fnp-3528	183	17	to	to	ADP
fnp-3528	183	18	the	the	DET
fnp-3528	183	19	rxr	rxr	NOUN
fnp-3528	183	20	receptor	receptor	NOUN
fnp-3528	183	21	and	and	CCONJ
fnp-3528	183	22	a	a	DET
fnp-3528	183	23	potential	potential	ADJ
fnp-3528	183	24	target	target	NOUN
fnp-3528	183	25	of	of	ADP
fnp-3528	183	26	retinoic	retinoic	ADJ
fnp-3528	183	27	acid	acid	NOUN
fnp-3528	183	28	derivatives	derivative	NOUN
fnp-3528	183	29	.	.	PUNCT
fnp-3528	184	1	to901317	to901317	NOUN
fnp-3528	184	2	and	and	CCONJ
fnp-3528	184	3	gw3965	gw3965	NOUN
fnp-3528	184	4	the	the	DET
fnp-3528	184	5	synthetic	synthetic	ADJ
fnp-3528	184	6	gold	gold	NOUN
fnp-3528	184	7	standard	standard	NOUN
fnp-3528	184	8	and	and	CCONJ
fnp-3528	184	9	most	most	ADV
fnp-3528	184	10	studied	studied	ADJ
fnp-3528	184	11	abca1	abca1	NOUN
fnp-3528	184	12	/	/	SYM
fnp-3528	184	13	abca1	abca1	NOUN
fnp-3528	184	14	inducer	inducer	NOUN
fnp-3528	184	15	in	in	ADP
fnp-3528	184	16	the	the	DET
fnp-3528	184	17	literature	literature	NOUN
fnp-3528	184	18	is	be	AUX
fnp-3528	184	19	to901317	to901317	ADJ
fnp-3528	184	20	(	(	PUNCT
fnp-3528	184	21	often	often	ADV
fnp-3528	184	22	referred	refer	VERB
fnp-3528	184	23	to	to	ADP
fnp-3528	184	24	as	as	ADP
fnp-3528	184	25	‘	'	PUNCT
fnp-3528	184	26	t0901317	t0901317	NOUN
fnp-3528	184	27	’	'	PUNCT
fnp-3528	184	28	;	;	PUNCT
fnp-3528	184	29	figure	figure	VERB
fnp-3528	184	30	2).205,245,250,252,259,260,262,264,271,272,279,280,282,308,310,317,319,322,324,326,328	2).205,245,250,252,259,260,262,264,271,272,279,280,282,308,310,317,319,322,324,326,328	NOUN
fnp-3528	184	31	-	-	SYM
fnp-3528	184	32	345	345	NUM
fnp-3528	184	33	to901317	to901317	NOUN
fnp-3528	184	34	targeted	target	VERB
fnp-3528	184	35	both	both	CCONJ
fnp-3528	184	36	the	the	DET
fnp-3528	184	37	lxr	lxr	NOUN
fnp-3528	184	38	α250,310,328,330,332,335,337	α250,310,328,330,332,335,337	PROPN
fnp-3528	184	39	-	-	SYM
fnp-3528	184	40	340,342	340,342	NUM
fnp-3528	184	41	and	and	CCONJ
fnp-3528	184	42	lxr	lxr	PROPN
fnp-3528	184	43	β	β	PROPN
fnp-3528	184	44	pathways,250,310,338,342	pathways,250,310,338,342	NOUN
fnp-3528	184	45	which	which	PRON
fnp-3528	184	46	correlated	correlate	VERB
fnp-3528	184	47	to	to	ADP
fnp-3528	184	48	abca1	abca1	NOUN
fnp-3528	184	49	/	/	SYM
fnp-3528	184	50	abca1	abca1	NOUN
fnp-3528	184	51	induction	induction	NOUN
fnp-3528	184	52	on	on	ADP
fnp-3528	184	53	mrna	mrna	PROPN
fnp-3528	184	54	and	and	CCONJ
fnp-3528	184	55	abca1	abca1	NOUN
fnp-3528	184	56	protein	protein	NOUN
fnp-3528	184	57	levels.205,250,279,282,310,319,322,324,326,328,330	levels.205,250,279,282,310,319,322,324,326,328,330	VERB
fnp-3528	184	58	-	-	PUNCT
fnp-3528	184	59	335,337	335,337	NUM
fnp-3528	184	60	-	-	PUNCT
fnp-3528	184	61	340,342,343	340,342,343	NUM
fnp-3528	184	62	in	in	ADP
fnp-3528	184	63	addition	addition	NOUN
fnp-3528	184	64	,	,	PUNCT
fnp-3528	184	65	an	an	DET
fnp-3528	184	66	induction	induction	NOUN
fnp-3528	184	67	of	of	ADP
fnp-3528	184	68	srebp1c	srebp1c	PROPN
fnp-3528	184	69	/	/	SYM
fnp-3528	184	70	srebp1c	srebp1c	PROPN
fnp-3528	184	71	has	have	AUX
fnp-3528	184	72	also	also	ADV
fnp-3528	184	73	been	be	AUX
fnp-3528	184	74	observed.336,342	observed.336,342	ADJ
fnp-3528	184	75	functionally	functionally	ADV
fnp-3528	184	76	,	,	PUNCT
fnp-3528	184	77	to901317	to901317	NOUN
fnp-3528	184	78	increased	increase	VERB
fnp-3528	184	79	cholesterol	cholesterol	NOUN
fnp-3528	184	80	efflux,250,259,260,262,264,282,319,324,329,331,342	efflux,250,259,260,262,264,282,319,324,329,331,342	NUM
fnp-3528	184	81	decreased	decrease	VERB
fnp-3528	184	82	intracellular	intracellular	ADJ
fnp-3528	184	83	aβ	aβ	PRON
fnp-3528	184	84	content	content	NOUN
fnp-3528	184	85	,	,	PUNCT
fnp-3528	184	86	and	and	CCONJ
fnp-3528	184	87	increased	increase	VERB
fnp-3528	184	88	aβ	aβ	PRON
fnp-3528	184	89	secretion	secretion	NOUN
fnp-3528	184	90	from	from	ADP
fnp-3528	184	91	different	different	ADJ
fnp-3528	184	92	murine	murine	ADJ
fnp-3528	184	93	brain	brain	NOUN
fnp-3528	184	94	cells.126,345	cells.126,345	PROPN
fnp-3528	184	95	further	far	ADV
fnp-3528	184	96	,	,	PUNCT
fnp-3528	184	97	it	it	PRON
fnp-3528	184	98	reduced	reduce	VERB
fnp-3528	184	99	aβ25	aβ25	PROPN
fnp-3528	184	100	-	-	PUNCT
fnp-3528	184	101	35	35	NUM
fnp-3528	184	102	-	-	PUNCT
fnp-3528	184	103	mediated	mediate	VERB
fnp-3528	184	104	toxicity	toxicity	NOUN
fnp-3528	184	105	toward	toward	ADP
fnp-3528	184	106	cells	cell	NOUN
fnp-3528	184	107	by	by	ADP
fnp-3528	184	108	induction	induction	NOUN
fnp-3528	184	109	of	of	ADP
fnp-3528	184	110	abca1.280	abca1.280	NOUN
fnp-3528	184	111	in	in	ADP
fnp-3528	184	112	addition	addition	NOUN
fnp-3528	184	113	,	,	PUNCT
fnp-3528	184	114	to901317	to901317	NOUN
fnp-3528	184	115	mitigated	mitigate	VERB
fnp-3528	184	116	memory	memory	NOUN
fnp-3528	184	117	deficits	deficit	NOUN
fnp-3528	184	118	in	in	ADP
fnp-3528	184	119	high	high	ADJ
fnp-3528	184	120	-	-	PUNCT
fnp-3528	184	121	fat	fat	NOUN
fnp-3528	184	122	diet	diet	NOUN
fnp-3528	184	123	-	-	PUNCT
fnp-3528	184	124	fed	feed	VERB
fnp-3528	184	125	app23	app23	PROPN
fnp-3528	184	126	mice	mouse	NOUN
fnp-3528	184	127	,	,	PUNCT
fnp-3528	184	128	reducing	reduce	VERB
fnp-3528	184	129	both	both	CCONJ
fnp-3528	184	130	plaque	plaque	NOUN
fnp-3528	184	131	and	and	CCONJ
fnp-3528	184	132	soluble	soluble	ADJ
fnp-3528	184	133	aβ	aβ	NOUN
fnp-3528	184	134	protein	protein	NOUN
fnp-3528	184	135	levels.344	levels.344	ADP
fnp-3528	184	136	besides	besides	ADV
fnp-3528	184	137	,	,	PUNCT
fnp-3528	184	138	to901317	to901317	NOUN
fnp-3528	184	139	reduced	reduce	VERB
fnp-3528	184	140	methionine-(homocysteine)-induced	methionine-(homocysteine)-induce	VERB
fnp-3528	184	141	atherosclerotic	atherosclerotic	ADJ
fnp-3528	184	142	lesions	lesion	NOUN
fnp-3528	184	143	in	in	ADP
fnp-3528	184	144	apoe	apoe	ADJ
fnp-3528	184	145	knock	knock	NOUN
fnp-3528	184	146	-	-	PUNCT
fnp-3528	184	147	out	out	ADP
fnp-3528	184	148	c57bl/6	c57bl/6	NOUN
fnp-3528	184	149	mice.335	mice.335	PROPN
fnp-3528	184	150	these	these	DET
fnp-3528	184	151	findings	finding	NOUN
fnp-3528	184	152	were	be	AUX
fnp-3528	184	153	paralleled	parallel	VERB
fnp-3528	184	154	by	by	ADP
fnp-3528	184	155	an	an	DET
fnp-3528	184	156	increase	increase	NOUN
fnp-3528	184	157	of	of	ADP
fnp-3528	184	158	abca1	abca1	PROPN
fnp-3528	184	159	mrna	mrna	PROPN
fnp-3528	184	160	and	and	CCONJ
fnp-3528	184	161	abca1	abca1	NOUN
fnp-3528	184	162	protein	protein	NOUN
fnp-3528	184	163	content,335	content,335	NOUN
fnp-3528	184	164	suggesting	suggest	VERB
fnp-3528	184	165	a	a	DET
fnp-3528	184	166	potential	potential	ADJ
fnp-3528	184	167	relevance	relevance	NOUN
fnp-3528	184	168	of	of	ADP
fnp-3528	184	169	to901217	to901217	NOUN
fnp-3528	184	170	in	in	ADP
fnp-3528	184	171	ad	ad	NOUN
fnp-3528	184	172	therapy	therapy	NOUN
fnp-3528	184	173	,	,	PUNCT
fnp-3528	184	174	although	although	SCONJ
fnp-3528	184	175	it	it	PRON
fnp-3528	184	176	must	must	AUX
fnp-3528	184	177	be	be	AUX
fnp-3528	184	178	taken	take	VERB
fnp-3528	184	179	into	into	ADP
fnp-3528	184	180	account	account	NOUN
fnp-3528	184	181	that	that	SCONJ
fnp-3528	184	182	lxr	lxr	ADJ
fnp-3528	184	183	activators	activator	NOUN
fnp-3528	184	184	,	,	PUNCT
fnp-3528	184	185	in	in	ADP
fnp-3528	184	186	particular	particular	ADJ
fnp-3528	184	187	to901317	to901317	NOUN
fnp-3528	184	188	,	,	PUNCT
fnp-3528	184	189	were	be	AUX
fnp-3528	184	190	demonstrated	demonstrate	VERB
fnp-3528	184	191	to	to	PART
fnp-3528	184	192	have	have	VERB
fnp-3528	184	193	severe	severe	ADJ
fnp-3528	184	194	side	side	NOUN
fnp-3528	184	195	effects	effect	NOUN
fnp-3528	184	196	in	in	ADP
fnp-3528	184	197	mice	mouse	NOUN
fnp-3528	184	198	,	,	PUNCT
fnp-3528	184	199	such	such	ADJ
fnp-3528	184	200	as	as	ADP
fnp-3528	184	201	neutropenia	neutropenia	NOUN
fnp-3528	184	202	,	,	PUNCT
fnp-3528	184	203	hypertriacylglycerolemia	hypertriacylglycerolemia	NOUN
fnp-3528	184	204	,	,	PUNCT
fnp-3528	184	205	hepatic	hepatic	ADJ
fnp-3528	184	206	triacylglycerol	triacylglycerol	NOUN
fnp-3528	184	207	accumulation	accumulation	NOUN
fnp-3528	184	208	,	,	PUNCT
fnp-3528	184	209	and	and	CCONJ
fnp-3528	184	210	hepatic	hepatic	NOUN
fnp-3528	184	211	steatosis.271,346,347	steatosis.271,346,347	PROPN
fnp-3528	184	212	the	the	DET
fnp-3528	184	213	second	second	ADJ
fnp-3528	184	214	most	most	ADV
fnp-3528	184	215	common	common	ADJ
fnp-3528	184	216	synthetic	synthetic	ADJ
fnp-3528	184	217	lxr	lxr	NOUN
fnp-3528	184	218	-	-	PUNCT
fnp-3528	184	219	α	α	PROPN
fnp-3528	184	220	and	and	CCONJ
fnp-3528	184	221	lxr	lxr	PROPN
fnp-3528	184	222	-	-	PUNCT
fnp-3528	185	1	β	β	NOUN
fnp-3528	185	2	agonist	agonist	NOUN
fnp-3528	185	3	is	be	AUX
fnp-3528	185	4	gw3965	gw3965	NOUN
fnp-3528	185	5	(	(	PUNCT
fnp-3528	185	6	figure	figure	NOUN
fnp-3528	185	7	 	 	SPACE
fnp-3528	185	8	2).255,272,317,319,321,334,348	2).255,272,317,319,321,334,348	NUM
fnp-3528	185	9	-	-	PUNCT
fnp-3528	185	10	352	352	NUM
fnp-3528	185	11	gw3965	gw3965	NOUN
fnp-3528	185	12	increased	increase	VERB
fnp-3528	185	13	mrna317,319,321,348,349,351,352	mrna317,319,321,348,349,351,352	NOUN
fnp-3528	185	14	and	and	CCONJ
fnp-3528	185	15	protein	protein	NOUN
fnp-3528	185	16	levels255,272,351	levels255,272,351	NOUN
fnp-3528	185	17	in	in	ADP
fnp-3528	185	18	different	different	ADJ
fnp-3528	185	19	abca1	abca1	NOUN
fnp-3528	185	20	-	-	PUNCT
fnp-3528	185	21	expressing	express	VERB
fnp-3528	185	22	cells	cell	NOUN
fnp-3528	185	23	.	.	PUNCT
fnp-3528	186	1	functionally	functionally	ADV
fnp-3528	186	2	,	,	PUNCT
fnp-3528	186	3	increased	increase	VERB
fnp-3528	186	4	abca1	abca1	NOUN
fnp-3528	186	5	mrna	mrna	PROPN
fnp-3528	186	6	and	and	CCONJ
fnp-3528	186	7	abca1	abca1	NOUN
fnp-3528	186	8	protein	protein	NOUN
fnp-3528	186	9	levels	level	NOUN
fnp-3528	186	10	correlated	correlate	VERB
fnp-3528	186	11	with	with	ADP
fnp-3528	186	12	enhanced	enhanced	ADJ
fnp-3528	186	13	cholesterol	cholesterol	NOUN
fnp-3528	186	14	efflux.255,351	efflux.255,351	PROPN
fnp-3528	186	15	strikingly	strikingly	ADV
fnp-3528	186	16	,	,	PUNCT
fnp-3528	186	17	exposure	exposure	NOUN
fnp-3528	186	18	of	of	ADP
fnp-3528	186	19	murine	murine	ADJ
fnp-3528	186	20	bv2	bv2	NOUN
fnp-3528	186	21	microglia	microglia	ADJ
fnp-3528	186	22	to	to	ADP
fnp-3528	186	23	gw3965	gw3965	NOUN
fnp-3528	186	24	reduced	reduce	VERB
fnp-3528	186	25	aβ42	aβ42	PROPN
fnp-3528	186	26	levels	level	NOUN
fnp-3528	186	27	due	due	ADJ
fnp-3528	186	28	to	to	ADP
fnp-3528	186	29	an	an	DET
fnp-3528	186	30	enhanced	enhanced	ADJ
fnp-3528	186	31	degradation	degradation	NOUN
fnp-3528	186	32	of	of	ADP
fnp-3528	186	33	aβ42,126	aβ42,126	NOUN
fnp-3528	186	34	suggesting	suggest	VERB
fnp-3528	186	35	that	that	DET
fnp-3528	186	36	abca1	abca1	NOUN
fnp-3528	186	37	contributes	contribute	VERB
fnp-3528	186	38	to	to	PART
fnp-3528	186	39	general	general	VERB
fnp-3528	186	40	aβ	aβ	PRON
fnp-3528	186	41	degradation	degradation	NOUN
fnp-3528	186	42	.	.	PUNCT
fnp-3528	187	1	finally	finally	ADV
fnp-3528	187	2	,	,	PUNCT
fnp-3528	187	3	gw3965	gw3965	PROPN
fnp-3528	187	4	significantly	significantly	ADV
fnp-3528	187	5	increased	increase	VERB
fnp-3528	187	6	abca1	abca1	NOUN
fnp-3528	187	7	transcription	transcription	NOUN
fnp-3528	187	8	in	in	ADP
fnp-3528	187	9	c57bl/6	c57bl/6	NOUN
fnp-3528	187	10	mice,334,351	mice,334,351	NOUN
fnp-3528	187	11	and	and	CCONJ
fnp-3528	187	12	improved	improve	VERB
fnp-3528	187	13	contextual	contextual	ADJ
fnp-3528	187	14	memory	memory	NOUN
fnp-3528	187	15	as	as	ADV
fnp-3528	187	16	well	well	ADV
fnp-3528	187	17	as	as	ADP
fnp-3528	187	18	aβ	aβ	DET
fnp-3528	187	19	pathology	pathology	NOUN
fnp-3528	187	20	in	in	ADP
fnp-3528	187	21	tg2576	tg2576	PROPN
fnp-3528	187	22	mice,126	mice,126	NOUN
fnp-3528	187	23	emphasizing	emphasize	VERB
fnp-3528	187	24	its	its	PRON
fnp-3528	187	25	high	high	ADJ
fnp-3528	187	26	relevance	relevance	NOUN
fnp-3528	187	27	in	in	ADP
fnp-3528	187	28	ad	ad	NOUN
fnp-3528	187	29	therapy	therapy	NOUN
fnp-3528	187	30	.	.	PUNCT
fnp-3528	188	1	abca1	abca1	PROPN
fnp-3528	188	2	other	other	ADJ
fnp-3528	188	3	lxr	lxr	PROPN
fnp-3528	188	4	agonists	agonist	NOUN
fnp-3528	188	5	and	and	CCONJ
fnp-3528	188	6	inducers	inducer	NOUN
fnp-3528	188	7	sterane	sterane	NOUN
fnp-3528	188	8	and	and	CCONJ
fnp-3528	188	9	sterane	sterane	NOUN
fnp-3528	188	10	-	-	PUNCT
fnp-3528	188	11	like	like	ADJ
fnp-3528	188	12	natural	natural	ADJ
fnp-3528	188	13	compounds	compound	NOUN
fnp-3528	188	14	several	several	ADJ
fnp-3528	188	15	sterane	sterane	NOUN
fnp-3528	188	16	derivatives	derivative	NOUN
fnp-3528	188	17	were	be	AUX
fnp-3528	188	18	demonstrated	demonstrate	VERB
fnp-3528	188	19	to	to	PART
fnp-3528	188	20	target	target	VERB
fnp-3528	188	21	lxr	lxr	PROPN
fnp-3528	188	22	-	-	PUNCT
fnp-3528	188	23	α	α	PROPN
fnp-3528	188	24	and	and	CCONJ
fnp-3528	188	25	lxr	lxr	PROPN
fnp-3528	188	26	-	-	PUNCT
fnp-3528	188	27	β	β	X
fnp-3528	188	28	activation253,307,310,353	activation253,307,310,353	PROPN
fnp-3528	188	29	and/or	and/or	CCONJ
fnp-3528	188	30	lxra	lxra	NOUN
fnp-3528	188	31	/	/	SYM
fnp-3528	188	32	lxra	lxra	NOUN
fnp-3528	188	33	and	and	CCONJ
fnp-3528	188	34	lxrb	lxrb	NOUN
fnp-3528	188	35	/	/	SYM
fnp-3528	188	36	lxrb	lxrb	PROPN
fnp-3528	188	37	upregulation,330,332,354,355,356,357	upregulation,330,332,354,355,356,357	NUM
fnp-3528	188	38	resulting	result	VERB
fnp-3528	188	39	in	in	ADP
fnp-3528	188	40	induction	induction	NOUN
fnp-3528	188	41	of	of	ADP
fnp-3528	188	42	abca1	abca1	NOUN
fnp-3528	188	43	/	/	SYM
fnp-3528	188	44	abca1	abca1	NOUN
fnp-3528	188	45	.	.	PUNCT
fnp-3528	189	1	celastrol,330,332	celastrol,330,332	NOUN
fnp-3528	189	2	digoxin,253	digoxin,253	VERB
fnp-3528	189	3	fuco	fuco	ADJ
fnp-3528	189	4	-	-	PUNCT
fnp-3528	189	5	sterol,308	sterol,308	ADV
fnp-3528	189	6	certain	certain	ADJ
fnp-3528	189	7	gypenosides,354	gypenosides,354	PROPN
fnp-3528	189	8	ouabain,253	ouabain,253	PROPN
fnp-3528	189	9	platy	platy	NOUN
fnp-3528	189	10	-	-	PUNCT
fnp-3528	189	11	codin	codin	ADJ
fnp-3528	189	12	d,355	d,355	PROPN
fnp-3528	189	13	saikosaponin	saikosaponin	NOUN
fnp-3528	189	14	a,356	a,356	VERB
fnp-3528	189	15	24-(s)-saringosterol,307	24-(s)-saringosterol,307	NUM
fnp-3528	189	16	24-(s)-stigmast-5	24-(s)-stigmast-5	NUM
fnp-3528	189	17	-	-	PUNCT
fnp-3528	189	18	ene-3β,24	ene-3β,24	NOUN
fnp-3528	189	19	-	-	PUNCT
fnp-3528	189	20	diol,307	diol,307	NOUN
fnp-3528	189	21	taxarasterol,353	taxarasterol,353	PROPN
fnp-3528	189	22	testosterone,357	testosterone,357	PROPN
fnp-3528	189	23	and	and	CCONJ
fnp-3528	189	24	tr1310	tr1310	PROPN
fnp-3528	190	1	increased	increase	VERB
fnp-3528	190	2	abca1	abca1	NOUN
fnp-3528	190	3	/	/	SYM
fnp-3528	190	4	abca1	abca1	NOUN
fnp-3528	190	5	mrna307,308,310,330,332,353,354,356,357	mrna307,308,310,330,332,353,354,356,357	X
fnp-3528	190	6	and/or	and/or	CCONJ
fnp-3528	190	7	abca1	abca1	NOUN
fnp-3528	190	8	protein	protein	NOUN
fnp-3528	190	9	content310,253,353,354,355,357	content310,253,353,354,355,357	NOUN
fnp-3528	190	10	leading	lead	VERB
fnp-3528	190	11	to	to	ADP
fnp-3528	190	12	an	an	DET
fnp-3528	190	13	enhanced	enhanced	ADJ
fnp-3528	190	14	efflux	efflux	NOUN
fnp-3528	190	15	of	of	ADP
fnp-3528	190	16	cholesterol	cholesterol	NOUN
fnp-3528	190	17	in	in	ADP
fnp-3528	190	18	vitro253,308,330,332	vitro253,308,330,332	NOUN
fnp-3528	190	19	and	and	CCONJ
fnp-3528	190	20	decreased	decrease	VERB
fnp-3528	190	21	intracellular	intracellular	ADJ
fnp-3528	190	22	cholesterol	cholesterol	NOUN
fnp-3528	190	23	and/or	and/or	CCONJ
fnp-3528	190	24	phospholipid	phospholipid	NOUN
fnp-3528	190	25	levels	level	NOUN
fnp-3528	190	26	in	in	ADP
fnp-3528	190	27	vitro330,332,354,356,357	vitro330,332,354,356,357	PROPN
fnp-3528	190	28	and	and	CCONJ
fnp-3528	190	29	in	in	ADP
fnp-3528	190	30	vivo	vivo	NOUN
fnp-3528	190	31	in	in	ADP
fnp-3528	190	32	mice.253	mice.253	NOUN
fnp-3528	190	33	the	the	DET
fnp-3528	190	34	effect	effect	NOUN
fnp-3528	190	35	of	of	ADP
fnp-3528	190	36	fucosterol	fucosterol	NOUN
fnp-3528	190	37	was	be	AUX
fnp-3528	190	38	comparable	comparable	ADJ
fnp-3528	190	39	to	to	ADP
fnp-3528	190	40	that	that	PRON
fnp-3528	190	41	of	of	ADP
fnp-3528	190	42	the	the	DET
fnp-3528	190	43	standard	standard	ADJ
fnp-3528	190	44	abca1	abca1	NOUN
fnp-3528	190	45	/	/	SYM
fnp-3528	190	46	abca1	abca1	NOUN
fnp-3528	190	47	inducer	inducer	NOUN
fnp-3528	190	48	to901317.308	to901317.308	ADP
fnp-3528	190	49	a	a	DET
fnp-3528	190	50	correlation	correlation	NOUN
fnp-3528	190	51	to	to	ADP
fnp-3528	190	52	srebp1(c	srebp1(c	VERB
fnp-3528	190	53	)	)	PUNCT
fnp-3528	190	54	upregulation308,307,357	upregulation308,307,357	PROPN
fnp-3528	190	55	and	and	CCONJ
fnp-3528	190	56	srebp1	srebp1	NOUN
fnp-3528	190	57	protein	protein	NOUN
fnp-3528	190	58	expression357	expression357	PROPN
fnp-3528	190	59	could	could	AUX
fnp-3528	190	60	be	be	AUX
fnp-3528	190	61	determined	determine	VERB
fnp-3528	190	62	in	in	ADP
fnp-3528	190	63	case	case	NOUN
fnp-3528	190	64	of	of	ADP
fnp-3528	190	65	fucosterol,308	fucosterol,308	PROPN
fnp-3528	190	66	24-(s)-saringosterol,307	24-(s)-saringosterol,307	NUM
fnp-3528	190	67	24-(s)-stigmast-5	24-(s)-stigmast-5	NUM
fnp-3528	190	68	-	-	PUNCT
fnp-3528	190	69	ene-3β,24	ene-3β,24	NOUN
fnp-3528	190	70	-	-	PUNCT
fnp-3528	190	71	diol,307	diol,307	NOUN
fnp-3528	190	72	and	and	CCONJ
fnp-3528	190	73	testosterone.357	testosterone.357	VERB
fnp-3528	190	74	in	in	ADP
fnp-3528	190	75	case	case	NOUN
fnp-3528	190	76	of	of	ADP
fnp-3528	190	77	celastrol	celastrol	NOUN
fnp-3528	190	78	,	,	PUNCT
fnp-3528	190	79	the	the	DET
fnp-3528	190	80	regulation	regulation	NOUN
fnp-3528	190	81	of	of	ADP
fnp-3528	190	82	intracellular	intracellular	ADJ
fnp-3528	190	83	cholesterol	cholesterol	NOUN
fnp-3528	190	84	was	be	AUX
fnp-3528	190	85	pinned	pin	VERB
fnp-3528	190	86	to	to	ADP
fnp-3528	190	87	an	an	DET
fnp-3528	190	88	activation	activation	NOUN
fnp-3528	190	89	of	of	ADP
fnp-3528	190	90	autophagy330,332	autophagy330,332	NOUN
fnp-3528	190	91	and	and	CCONJ
fnp-3528	190	92	lipophagy,330	lipophagy,330	PROPN
fnp-3528	190	93	which	which	PRON
fnp-3528	190	94	are	be	AUX
fnp-3528	190	95	processes	process	NOUN
fnp-3528	190	96	that	that	PRON
fnp-3528	190	97	may	may	AUX
fnp-3528	190	98	be	be	AUX
fnp-3528	190	99	associated	associate	VERB
fnp-3528	190	100	with	with	ADP
fnp-3528	190	101	aβ	aβ	DET
fnp-3528	190	102	degradation	degradation	NOUN
fnp-3528	190	103	.	.	PUNCT
fnp-3528	191	1	flavonoids	flavonoid	NOUN
fnp-3528	191	2	the	the	DET
fnp-3528	191	3	flavonoids	flavonoid	NOUN
fnp-3528	191	4	naringenin,339	naringenin,339	PROPN
fnp-3528	191	5	quercetin,358	quercetin,358	NOUN
fnp-3528	191	6	and	and	CCONJ
fnp-3528	191	7	vitexin359	vitexin359	PROPN
fnp-3528	191	8	increased	increase	VERB
fnp-3528	191	9	abca1	abca1	NOUN
fnp-3528	191	10	/	/	SYM
fnp-3528	191	11	abca1	abca1	NOUN
fnp-3528	191	12	mrna339,359	mrna339,359	X
fnp-3528	191	13	and	and	CCONJ
fnp-3528	191	14	abca1	abca1	NOUN
fnp-3528	191	15	protein	protein	NOUN
fnp-3528	191	16	levels339,360,358	levels339,360,358	PROPN
fnp-3528	191	17	by	by	ADP
fnp-3528	191	18	induction	induction	NOUN
fnp-3528	191	19	of	of	ADP
fnp-3528	191	20	lxra	lxra	NOUN
fnp-3528	191	21	/	/	SYM
fnp-3528	191	22	lxra	lxra	NOUN
fnp-3528	191	23	mrna358,359	mrna358,359	NOUN
fnp-3528	191	24	and	and	CCONJ
fnp-3528	191	25	lxr	lxr	PROPN
fnp-3528	191	26	-	-	PUNCT
fnp-3528	191	27	α	α	NOUN
fnp-3528	191	28	protein.339,360	protein.339,360	PROPN
fnp-3528	191	29	the	the	DET
fnp-3528	191	30	effect	effect	NOUN
fnp-3528	191	31	of	of	ADP
fnp-3528	191	32	naringenin	naringenin	NOUN
fnp-3528	191	33	and	and	CCONJ
fnp-3528	191	34	the	the	DET
fnp-3528	191	35	standard	standard	ADJ
fnp-3528	191	36	abca1	abca1	NOUN
fnp-3528	191	37	/	/	SYM
fnp-3528	191	38	abca1	abca1	NOUN
fnp-3528	191	39	inducer	inducer	NOUN
fnp-3528	191	40	to901317	to901317	PROPN
fnp-3528	191	41	were	be	AUX
fnp-3528	191	42	additive	additive	ADJ
fnp-3528	191	43	.	.	PUNCT
fnp-3528	192	1	naringenin	naringenin	PROPN
fnp-3528	192	2	was	be	AUX
fnp-3528	192	3	shown	show	VERB
fnp-3528	192	4	to	to	PART
fnp-3528	192	5	be	be	AUX
fnp-3528	192	6	dependent	dependent	ADJ
fnp-3528	192	7	on	on	ADP
fnp-3528	192	8	the	the	DET
fnp-3528	192	9	camp	camp	NOUN
fnp-3528	192	10	-	-	PUNCT
fnp-3528	192	11	activated	activate	VERB
fnp-3528	192	12	protein	protein	NOUN
fnp-3528	192	13	kinase	kinase	NOUN
fnp-3528	192	14	(	(	PUNCT
fnp-3528	192	15	ampk	ampk	NOUN
fnp-3528	192	16	)	)	PUNCT
fnp-3528	192	17	regulation	regulation	NOUN
fnp-3528	192	18	(	(	PUNCT
fnp-3528	192	19	ampk	ampk	NOUN
fnp-3528	192	20	)	)	PUNCT
fnp-3528	192	21	,	,	PUNCT
fnp-3528	192	22	as	as	ADV
fnp-3528	192	23	well	well	ADV
fnp-3528	192	24	as	as	ADP
fnp-3528	192	25	srebp1c	srebp1c	PROPN
fnp-3528	192	26	regulation.339	regulation.339	VERB
fnp-3528	192	27	the	the	DET
fnp-3528	192	28	ampk	ampk	NOUN
fnp-3528	192	29	pathway	pathway	NOUN
fnp-3528	192	30	is	be	AUX
fnp-3528	192	31	another	another	DET
fnp-3528	192	32	very	very	ADV
fnp-3528	192	33	important	important	ADJ
fnp-3528	192	34	regulator	regulator	NOUN
fnp-3528	192	35	of	of	ADP
fnp-3528	192	36	abca1	abca1	NOUN
fnp-3528	192	37	expression	expression	NOUN
fnp-3528	192	38	.	.	PUNCT
fnp-3528	193	1	functionally	functionally	ADV
fnp-3528	193	2	,	,	PUNCT
fnp-3528	193	3	cholesterol	cholesterol	NOUN
fnp-3528	193	4	efflux	efflux	VERB
fnp-3528	193	5	from	from	ADP
fnp-3528	193	6	human339,360	human339,360	NOUN
fnp-3528	193	7	and	and	CCONJ
fnp-3528	193	8	murine360	murine360	PROPN
fnp-3528	193	9	macrophages	macrophage	NOUN
fnp-3528	193	10	was	be	AUX
fnp-3528	193	11	increased	increase	VERB
fnp-3528	193	12	in	in	ADP
fnp-3528	193	13	the	the	DET
fnp-3528	193	14	presence	presence	NOUN
fnp-3528	193	15	of	of	ADP
fnp-3528	193	16	naringenin.339,360	naringenin.339,360	NOUN
fnp-3528	193	17	in	in	ADP
fnp-3528	193	18	vivo	vivo	NOUN
fnp-3528	193	19	,	,	PUNCT
fnp-3528	193	20	naringenin	naringenin	NOUN
fnp-3528	193	21	and	and	CCONJ
fnp-3528	193	22	quercetin	quercetin	NOUN
fnp-3528	193	23	induced	induce	VERB
fnp-3528	193	24	abca1360	abca1360	NOUN
fnp-3528	193	25	and	and	CCONJ
fnp-3528	193	26	abca1,361,362	abca1,361,362	PROPN
fnp-3528	193	27	as	as	ADV
fnp-3528	193	28	well	well	ADV
fnp-3528	193	29	as	as	ADP
fnp-3528	193	30	abca1	abca1	NOUN
fnp-3528	193	31	-	-	PUNCT
fnp-3528	193	32	mediated	mediate	VERB
fnp-3528	193	33	cholesterol	cholesterol	NOUN
fnp-3528	193	34	transport,360	transport,360	NOUN
fnp-3528	193	35	which	which	PRON
fnp-3528	193	36	was	be	AUX
fnp-3528	193	37	reflected	reflect	VERB
fnp-3528	193	38	in	in	ADP
fnp-3528	193	39	reduced	reduce	VERB
fnp-3528	193	40	atherosclerotic	atherosclerotic	ADJ
fnp-3528	193	41	lesions	lesion	NOUN
fnp-3528	193	42	in	in	ADP
fnp-3528	193	43	the	the	DET
fnp-3528	193	44	aorta	aorta	NOUN
fnp-3528	193	45	of	of	ADP
fnp-3528	193	46	high	high	ADJ
fnp-3528	193	47	-	-	PUNCT
fnp-3528	193	48	fat	fat	NOUN
fnp-3528	193	49	diet	diet	NOUN
fnp-3528	193	50	-	-	PUNCT
fnp-3528	193	51	fed	feed	VERB
fnp-3528	193	52	c57bl/6	c57bl/6	NOUN
fnp-3528	193	53	mice.360	mice.360	NOUN
fnp-3528	193	54	in	in	ADP
fnp-3528	193	55	terms	term	NOUN
fnp-3528	193	56	of	of	ADP
fnp-3528	193	57	quercetin	quercetin	NOUN
fnp-3528	193	58	,	,	PUNCT
fnp-3528	193	59	a	a	DET
fnp-3528	193	60	protein	protein	NOUN
fnp-3528	193	61	increase	increase	NOUN
fnp-3528	193	62	of	of	ADP
fnp-3528	193	63	lxr	lxr	PROPN
fnp-3528	193	64	-	-	PUNCT
fnp-3528	193	65	α	α	NOUN
fnp-3528	193	66	and	and	CCONJ
fnp-3528	193	67	ppar	ppar	NOUN
fnp-3528	193	68	-	-	PUNCT
fnp-3528	193	69	γ	γ	NOUN
fnp-3528	193	70	was	be	AUX
fnp-3528	193	71	observed.361	observed.361	NOUN
fnp-3528	193	72	chalcones	chalcone	NOUN
fnp-3528	193	73	,	,	PUNCT
fnp-3528	193	74	the	the	DET
fnp-3528	193	75	precursors	precursor	NOUN
fnp-3528	193	76	of	of	ADP
fnp-3528	193	77	flavonoid	flavonoid	NOUN
fnp-3528	193	78	biosynthesis	biosynthesis	NOUN
fnp-3528	193	79	,	,	PUNCT
fnp-3528	193	80	were	be	AUX
fnp-3528	193	81	also	also	ADV
fnp-3528	193	82	demonstrated	demonstrate	VERB
fnp-3528	193	83	to	to	PART
fnp-3528	193	84	intervene	intervene	VERB
fnp-3528	193	85	with	with	ADP
fnp-3528	193	86	abca1	abca1	NOUN
fnp-3528	193	87	expression	expression	NOUN
fnp-3528	193	88	.	.	PUNCT
fnp-3528	194	1	the	the	DET
fnp-3528	194	2	chalcone	chalcone	NOUN
fnp-3528	194	3	derivatives	derivative	VERB
fnp-3528	194	4	1h,363	1h,363	NOUN
fnp-3528	194	5	1m,363,364	1m,363,364	NUM
fnp-3528	194	6	and	and	CCONJ
fnp-3528	194	7	1m-6364	1m-6364	NUM
fnp-3528	194	8	were	be	AUX
fnp-3528	194	9	demonstrated	demonstrate	VERB
fnp-3528	194	10	to	to	PART
fnp-3528	194	11	increase	increase	VERB
fnp-3528	194	12	abca1	abca1	NOUN
fnp-3528	194	13	mrna	mrna	NOUN
fnp-3528	194	14	and	and	CCONJ
fnp-3528	194	15	abca1	abca1	NOUN
fnp-3528	194	16	protein	protein	NOUN
fnp-3528	194	17	levels	level	NOUN
fnp-3528	194	18	in	in	ADP
fnp-3528	194	19	thp-1	thp-1	NUM
fnp-3528	194	20	macrophages,363,364	macrophages,363,364	NOUN
fnp-3528	194	21	which	which	PRON
fnp-3528	194	22	was	be	AUX
fnp-3528	194	23	accompanied	accompany	VERB
fnp-3528	194	24	by	by	ADP
fnp-3528	194	25	an	an	DET
fnp-3528	194	26	increase	increase	NOUN
fnp-3528	194	27	in	in	ADP
fnp-3528	194	28	lxra	lxra	NOUN
fnp-3528	194	29	mrna	mrna	NOUN
fnp-3528	194	30	and	and	CCONJ
fnp-3528	194	31	lxr	lxr	PROPN
fnp-3528	194	32	-	-	PUNCT
fnp-3528	194	33	α	α	NOUN
fnp-3528	194	34	protein	protein	NOUN
fnp-3528	194	35	levels.363	levels.363	VERB
fnp-3528	194	36	the	the	DET
fnp-3528	194	37	intracellular	intracellular	ADJ
fnp-3528	194	38	lipid	lipid	NOUN
fnp-3528	194	39	content	content	NOUN
fnp-3528	194	40	was	be	AUX
fnp-3528	194	41	decreased	decrease	VERB
fnp-3528	194	42	,	,	PUNCT
fnp-3528	194	43	while	while	SCONJ
fnp-3528	194	44	the	the	DET
fnp-3528	194	45	cholesterol	cholesterol	NOUN
fnp-3528	194	46	efflux	efflux	NOUN
fnp-3528	194	47	was	be	AUX
fnp-3528	194	48	increased	increase	VERB
fnp-3528	194	49	after	after	ADP
fnp-3528	194	50	exposure	exposure	NOUN
fnp-3528	194	51	of	of	ADP
fnp-3528	194	52	thp1	thp1	NOUN
fnp-3528	194	53	-	-	PUNCT
fnp-3528	194	54	cells	cell	NOUN
fnp-3528	194	55	to	to	ADP
fnp-3528	194	56	1m-6.364	1m-6.364	NOUN
fnp-3528	194	57	in	in	ADP
fnp-3528	194	58	addition	addition	NOUN
fnp-3528	194	59	,	,	PUNCT
fnp-3528	194	60	srebp1	srebp1	NOUN
fnp-3528	194	61	mrna	mrna	PROPN
fnp-3528	194	62	was	be	AUX
fnp-3528	194	63	increased	increase	VERB
fnp-3528	194	64	by	by	ADP
fnp-3528	194	65	1m-6,364	1m-6,364	NUM
fnp-3528	194	66	and	and	CCONJ
fnp-3528	194	67	aortic	aortic	ADJ
fnp-3528	194	68	atherosclerotic	atherosclerotic	ADJ
fnp-3528	194	69	plaques	plaque	NOUN
fnp-3528	194	70	were	be	AUX
fnp-3528	194	71	reduced	reduce	VERB
fnp-3528	194	72	in	in	ADP
fnp-3528	194	73	ldlr	ldlr	ADJ
fnp-3528	194	74	knock	knock	VERB
fnp-3528	194	75	-	-	PUNCT
fnp-3528	194	76	out	out	ADP
fnp-3528	194	77	c57bl/6	c57bl/6	NOUN
fnp-3528	194	78	mice.364	mice.364	NOUN
fnp-3528	194	79	polyphenols	polyphenol	NOUN
fnp-3528	194	80	and	and	CCONJ
fnp-3528	194	81	diterpenoid	diterpenoid	ADJ
fnp-3528	194	82	natural	natural	ADJ
fnp-3528	194	83	compounds	compound	NOUN
fnp-3528	194	84	the	the	DET
fnp-3528	194	85	polyphenols	polyphenol	NOUN
fnp-3528	194	86	kuwanon	kuwanon	PROPN
fnp-3528	194	87	g,365	g,365	PROPN
fnp-3528	194	88	paeonol,252	paeonol,252	VERB
fnp-3528	194	89	the	the	DET
fnp-3528	194	90	celtis	celtis	ADJ
fnp-3528	194	91	biondii	biondii	NOUN
fnp-3528	194	92	-	-	PUNCT
fnp-3528	194	93	derived	derive	VERB
fnp-3528	194	94	compound	compound	NOUN
fnp-3528	195	1	ethyl	ethyl	PROPN
fnp-3528	195	2	2,4,6	2,4,6	NUM
fnp-3528	195	3	-	-	PUNCT
fnp-3528	195	4	trihydroxybenzoate,342	trihydroxybenzoate,342	NOUN
fnp-3528	196	1	and	and	CCONJ
fnp-3528	196	2	the	the	DET
fnp-3528	196	3	diterpenoid	diterpenoid	PROPN
fnp-3528	196	4	farnesin366	farnesin366	PROPN
fnp-3528	196	5	increased	increase	VERB
fnp-3528	196	6	abca1	abca1	NOUN
fnp-3528	196	7	/	/	SYM
fnp-3528	196	8	abca1	abca1	NOUN
fnp-3528	196	9	mrna252,342,365,366	mrna252,342,365,366	NOUN
fnp-3528	196	10	and	and	CCONJ
fnp-3528	196	11	abca1	abca1	VERB
fnp-3528	196	12	protein252,342,365,366	protein252,342,365,366	ADJ
fnp-3528	196	13	content	content	NOUN
fnp-3528	196	14	in	in	ADP
fnp-3528	196	15	an	an	DET
fnp-3528	196	16	lxr	lxr	PROPN
fnp-3528	196	17	-	-	PUNCT
fnp-3528	196	18	α-252,366	α-252,366	PROPN
fnp-3528	196	19	and	and	CCONJ
fnp-3528	196	20	lxr	lxr	PROPN
fnp-3528	196	21	-	-	PUNCT
fnp-3528	196	22	β	β	NOUN
fnp-3528	196	23	-	-	PUNCT
fnp-3528	196	24	dependent342	dependent342	PROPN
fnp-3528	196	25	manner	manner	NOUN
fnp-3528	196	26	,	,	PUNCT
fnp-3528	196	27	which	which	PRON
fnp-3528	196	28	in	in	ADP
fnp-3528	196	29	parallel	parallel	ADJ
fnp-3528	196	30	reduced	reduce	VERB
fnp-3528	196	31	cholesterol	cholesterol	NOUN
fnp-3528	196	32	content252	content252	PROPN
fnp-3528	196	33	and	and	CCONJ
fnp-3528	196	34	increased	increase	VERB
fnp-3528	196	35	abca1	abca1	NOUN
fnp-3528	196	36	-	-	PUNCT
fnp-3528	196	37	mediated	mediate	VERB
fnp-3528	196	38	cholesterol	cholesterol	NOUN
fnp-3528	196	39	efflux	efflux	NOUN
fnp-3528	196	40	in	in	ADP
fnp-3528	196	41	various	various	ADJ
fnp-3528	196	42	cell	cell	NOUN
fnp-3528	196	43	lines.252,342,366	lines.252,342,366	PROPN
fnp-3528	196	44	in	in	ADP
fnp-3528	196	45	vivo	vivo	NOUN
fnp-3528	196	46	,	,	PUNCT
fnp-3528	196	47	farnesin	farnesin	NOUN
fnp-3528	196	48	increased	increase	VERB
fnp-3528	196	49	abca1	abca1	NOUN
fnp-3528	196	50	protein	protein	NOUN
fnp-3528	196	51	content	content	NOUN
fnp-3528	196	52	and	and	CCONJ
fnp-3528	196	53	cholesterol	cholesterol	NOUN
fnp-3528	196	54	efflux	efflux	VERB
fnp-3528	196	55	in	in	ADP
fnp-3528	196	56	apoe	apoe	ADJ
fnp-3528	196	57	knock	knock	NOUN
fnp-3528	196	58	-	-	PUNCT
fnp-3528	196	59	out	out	ADP
fnp-3528	196	60	c57bl/6	c57bl/6	NOUN
fnp-3528	196	61	mice	mouse	NOUN
fnp-3528	196	62	in	in	ADP
fnp-3528	196	63	primary	primary	ADJ
fnp-3528	196	64	peritoneal	peritoneal	ADJ
fnp-3528	196	65	macrophages	macrophage	NOUN
fnp-3528	196	66	and	and	CCONJ
fnp-3528	196	67	the	the	DET
fnp-3528	196	68	aorta	aorta	NOUN
fnp-3528	196	69	,	,	PUNCT
fnp-3528	196	70	which	which	PRON
fnp-3528	196	71	was	be	AUX
fnp-3528	196	72	reflected	reflect	VERB
fnp-3528	196	73	in	in	ADP
fnp-3528	196	74	reduced	reduce	VERB
fnp-3528	196	75	atherosclerotic	atherosclerotic	ADJ
fnp-3528	196	76	plaques.366	plaques.366	PROPN
fnp-3528	196	77	other	other	ADJ
fnp-3528	196	78	natural	natural	ADJ
fnp-3528	196	79	compounds	compound	NOUN
fnp-3528	196	80	several	several	ADJ
fnp-3528	196	81	other	other	ADJ
fnp-3528	196	82	natural	natural	ADJ
fnp-3528	196	83	compounds	compound	NOUN
fnp-3528	196	84	induced	induce	VERB
fnp-3528	196	85	abca1	abca1	NOUN
fnp-3528	196	86	/	/	SYM
fnp-3528	196	87	abca1	abca1	NOUN
fnp-3528	196	88	targeting	target	VERB
fnp-3528	196	89	lxr	lxr	PROPN
fnp-3528	196	90	-	-	PUNCT
fnp-3528	196	91	α	α	PROPN
fnp-3528	196	92	and	and	CCONJ
fnp-3528	196	93	lxr	lxr	PROPN
fnp-3528	196	94	-	-	PUNCT
fnp-3528	196	95	β	β	X
fnp-3528	196	96	activation256,272,256,349,367	activation256,272,256,349,367	NOUN
fnp-3528	196	97	and/or	and/or	CCONJ
fnp-3528	196	98	lxra	lxra	NOUN
fnp-3528	196	99	/	/	SYM
fnp-3528	196	100	lxra	lxra	NOUN
fnp-3528	196	101	and	and	CCONJ
fnp-3528	196	102	lxrb	lxrb	NOUN
fnp-3528	196	103	/	/	SYM
fnp-3528	196	104	lxrb	lxrb	PROPN
fnp-3528	196	105	induction.331,348,350,368,369,370,371,372,373,374	induction.331,348,350,368,369,370,371,372,373,374	X
fnp-3528	196	106	the	the	DET
fnp-3528	196	107	garlic	garlic	PROPN
fnp-3528	196	108	ingredient	ingredient	NOUN
fnp-3528	196	109	allicin,350	allicin,350	PROPN
fnp-3528	196	110	the	the	DET
fnp-3528	196	111	alkaloid	alkaloid	PROPN
fnp-3528	196	112	berberine,256	berberine,256	PROPN
fnp-3528	197	1	the	the	DET
fnp-3528	197	2	coumarin	coumarin	NOUN
fnp-3528	197	3	bergapten	bergapten	VERB
fnp-3528	197	4	a,368	a,368	PROPN
fnp-3528	197	5	certain	certain	ADJ
fnp-3528	197	6	pestalotiopsis	pestalotiopsis	NOUN
fnp-3528	197	7	neglecta	neglecta	ADV
fnp-3528	197	8	-	-	PUNCT
fnp-3528	197	9	derived	derive	VERB
fnp-3528	197	10	chromene	chromene	NOUN
fnp-3528	197	11	derivatives,348	derivatives,348	ADP
fnp-3528	197	12	the	the	DET
fnp-3528	197	13	rheum	rheum	NOUN
fnp-3528	197	14	palmatum	palmatum	NOUN
fnp-3528	197	15	-	-	PUNCT
fnp-3528	197	16	derived	derive	VERB
fnp-3528	197	17	anthra	anthra	NOUN
fnp-3528	197	18	-	-	PUNCT
fnp-3528	197	19	quinone	quinone	NOUN
fnp-3528	197	20	danthron,369	danthron,369	NOUN
fnp-3528	197	21	the	the	DET
fnp-3528	197	22	lacton	lacton	PROPN
fnp-3528	197	23	1,6	1,6	NUM
fnp-3528	197	24	-	-	PUNCT
fnp-3528	197	25	o	o	NOUN
fnp-3528	197	26	,	,	PUNCT
fnp-3528	197	27	o	o	ADJ
fnp-3528	197	28	-	-	ADJ
fnp-3528	197	29	diacetylbritannilactone,371	diacetylbritannilactone,371	ADV
fnp-3528	197	30	epigallocatechin	epigallocatechin	PROPN
fnp-3528	197	31	gallate	gallate	PROPN
fnp-3528	197	32	(	(	PUNCT
fnp-3528	197	33	egcg),370	egcg),370	X
fnp-3528	197	34	the	the	DET
fnp-3528	197	35	glycoside	glycoside	NOUN
fnp-3528	197	36	geniposide,375	geniposide,375	VERB
fnp-3528	197	37	the	the	DET
fnp-3528	197	38	vegetable	vegetable	NOUN
fnp-3528	197	39	ingredient	ingredient	NOUN
fnp-3528	197	40	phenethyl	phenethyl	NOUN
fnp-3528	197	41	isothiocyanate,373	isothiocyanate,373	VERB
fnp-3528	197	42	the	the	DET
fnp-3528	197	43	carotenoid	carotenoid	NOUN
fnp-3528	197	44	lycopene,372	lycopene,372	VERB
fnp-3528	198	1	the	the	DET
fnp-3528	198	2	pestalotiopsis	pestalotiopsis	NOUN
fnp-3528	198	3	neglecta	neglecta	ADV
fnp-3528	198	4	-	-	PUNCT
fnp-3528	198	5	derived	derive	VERB
fnp-3528	198	6	hydroquinone	hydroquinone	NOUN
fnp-3528	198	7	pestalotioquinoside	pestalotioquinoside	NOUN
fnp-3528	198	8	c,349	c,349	NOUN
fnp-3528	198	9	the	the	DET
fnp-3528	198	10	alkaloid	alkaloid	NOUN
fnp-3528	198	11	rutaecarpine,367	rutaecarpine,367	NOUN
fnp-3528	198	12	selenium,374	selenium,374	ADV
fnp-3528	199	1	the	the	DET
fnp-3528	199	2	macro	macro	NOUN
fnp-3528	199	3	-	-	ADJ
fnp-3528	199	4	lactone	lactone	ADJ
fnp-3528	199	5	soraphene	soraphene	NOUN
fnp-3528	199	6	a,272	a,272	PROPN
fnp-3528	199	7	and	and	CCONJ
fnp-3528	199	8	vitamin	vitamin	NOUN
fnp-3528	199	9	d3331	d3331	PROPN
fnp-3528	199	10	led	lead	VERB
fnp-3528	199	11	to	to	ADP
fnp-3528	199	12	increased	increase	VERB
fnp-3528	199	13	abca1	abca1	NOUN
fnp-3528	199	14	/	/	SYM
fnp-3528	199	15	abca1	abca1	NOUN
fnp-3528	199	16	mrna256,272,331,348,369,256,367,370,372,373	mrna256,272,331,348,369,256,367,370,372,373	NOUN
fnp-3528	199	17	and	and	CCONJ
fnp-3528	199	18	abca1	abca1	NOUN
fnp-3528	199	19	protein256,272,331,349,350,368,369,256,367,371,373,374	protein256,272,331,349,350,368,369,256,367,371,373,374	NOUN
fnp-3528	199	20	content	content	NOUN
fnp-3528	199	21	in	in	ADP
fnp-3528	199	22	vitro331,349,350,369,375,374	vitro331,349,350,369,375,374	PROPN
fnp-3528	199	23	and	and	CCONJ
fnp-3528	199	24	in	in	ADP
fnp-3528	199	25	vivo,368,369,370,371,372,373	vivo,368,369,370,371,372,373	NOUN
fnp-3528	199	26	enhancing	enhance	VERB
fnp-3528	199	27	cellular	cellular	ADJ
fnp-3528	199	28	cholesterol	cholesterol	NOUN
fnp-3528	199	29	efflux256,272,256,367,369	efflux256,272,256,367,369	PROPN
fnp-3528	199	30	and	and	CCONJ
fnp-3528	199	31	reducing	reduce	VERB
fnp-3528	199	32	intracellular	intracellular	ADJ
fnp-3528	199	33	cholesterol	cholesterol	NOUN
fnp-3528	199	34	con	con	NOUN
fnp-3528	199	35	-	-	PUNCT
fnp-3528	199	36	tent.331,350,369,256,367,375,372,374	tent.331,350,369,256,367,375,372,374	NOUN
fnp-3528	199	37	danthron	danthron	NOUN
fnp-3528	199	38	also	also	ADV
fnp-3528	199	39	increased	increase	VERB
fnp-3528	199	40	ampk	ampk	NOUN
fnp-3528	199	41	protein	protein	NOUN
fnp-3528	199	42	levels,369	levels,369	ADJ
fnp-3528	199	43	while	while	SCONJ
fnp-3528	199	44	egcg	egcg	NOUN
fnp-3528	199	45	downregulated	downregulate	VERB
fnp-3528	199	46	srebp1	srebp1	PROPN
fnp-3528	199	47	mrna	mrna	PROPN
fnp-3528	199	48	and	and	CCONJ
fnp-3528	199	49	srebp1	srebp1	NOUN
fnp-3528	199	50	protein	protein	NOUN
fnp-3528	199	51	content.370	content.370	PROPN
fnp-3528	199	52	lycopene	lycopene	NOUN
fnp-3528	199	53	induced	induce	VERB
fnp-3528	199	54	ppara	ppara	PROPN
fnp-3528	199	55	mrna	mrna	PROPN
fnp-3528	199	56	in	in	ADP
fnp-3528	199	57	tobacco	tobacco	NOUN
fnp-3528	199	58	carcinogenand	carcinogenand	NOUN
fnp-3528	199	59	cigarette	cigarette	NOUN
fnp-3528	199	60	smoke	smoke	NOUN
fnp-3528	199	61	-	-	PUNCT
fnp-3528	199	62	exposed	expose	VERB
fnp-3528	199	63	ferrets,372	ferrets,372	NOUN
fnp-3528	199	64	while	while	SCONJ
fnp-3528	199	65	isothiocyanate	isothiocyanate	ADJ
fnp-3528	199	66	induced	induce	VERB
fnp-3528	199	67	pparg	pparg	NOUN
fnp-3528	199	68	mrna	mrna	PROPN
fnp-3528	199	69	as	as	ADV
fnp-3528	199	70	well	well	ADV
fnp-3528	199	71	as	as	ADP
fnp-3528	199	72	ppar	ppar	NOUN
fnp-3528	199	73	-	-	PUNCT
fnp-3528	199	74	γ	γ	NOUN
fnp-3528	199	75	protein	protein	NOUN
fnp-3528	199	76	content	content	NOUN
fnp-3528	199	77	in	in	ADP
fnp-3528	199	78	high	high	ADJ
fnp-3528	199	79	fat	fat	ADJ
fnp-3528	199	80	diet	diet	NOUN
fnp-3528	199	81	-	-	PUNCT
fnp-3528	199	82	fed	feed	VERB
fnp-3528	199	83	c57bl/6	c57bl/6	NOUN
fnp-3528	199	84	mice.373	mice.373	NOUN
fnp-3528	199	85	the	the	DET
fnp-3528	199	86	inducing	inducing	ADJ
fnp-3528	199	87	effects	effect	NOUN
fnp-3528	199	88	on	on	ADP
fnp-3528	199	89	abca1	abca1	NOUN
fnp-3528	199	90	expression	expression	NOUN
fnp-3528	199	91	of	of	ADP
fnp-3528	199	92	vitamin	vitamin	NOUN
fnp-3528	199	93	d3	d3	PROPN
fnp-3528	199	94	and	and	CCONJ
fnp-3528	199	95	to901317	to901317	NOUN
fnp-3528	199	96	were	be	AUX
fnp-3528	199	97	additive.331	additive.331	PROPN
fnp-3528	199	98	danthron	danthron	NOUN
fnp-3528	199	99	,	,	PUNCT
fnp-3528	199	100	egcg	egcg	NOUN
fnp-3528	199	101	,	,	PUNCT
fnp-3528	199	102	geniposide	geniposide	ADJ
fnp-3528	199	103	,	,	PUNCT
fnp-3528	199	104	and	and	CCONJ
fnp-3528	199	105	rutaecarpine	rutaecarpine	NOUN
fnp-3528	199	106	demonstrated	demonstrate	VERB
fnp-3528	199	107	also	also	ADV
fnp-3528	199	108	reduced	reduce	VERB
fnp-3528	199	109	atherosclerotic	atherosclerotic	ADJ
fnp-3528	199	110	lesions	lesion	NOUN
fnp-3528	199	111	in	in	ADP
fnp-3528	199	112	apoe	apoe	ADJ
fnp-3528	199	113	knock	knock	NOUN
fnp-3528	199	114	-	-	PUNCT
fnp-3528	199	115	out	out	ADP
fnp-3528	199	116	c57bl/6	c57bl/6	NOUN
fnp-3528	199	117	mice,369,370,375,367	mice,369,370,375,367	NOUN
fnp-3528	199	118	and	and	CCONJ
fnp-3528	199	119	isothiocyanate	isothiocyanate	NOUN
fnp-3528	199	120	ameliorated	ameliorate	VERB
fnp-3528	199	121	the	the	DET
fnp-3528	199	122	aortic	aortic	ADJ
fnp-3528	199	123	injury	injury	NOUN
fnp-3528	199	124	of	of	ADP
fnp-3528	199	125	the	the	DET
fnp-3528	199	126	high	high	ADJ
fnp-3528	199	127	-	-	PUNCT
fnp-3528	199	128	fat	fat	NOUN
fnp-3528	199	129	diet	diet	NOUN
fnp-3528	199	130	in	in	ADP
fnp-3528	199	131	the	the	DET
fnp-3528	199	132	same	same	ADJ
fnp-3528	199	133	mice.373	mice.373	PROPN
fnp-3528	199	134	pharmacological	pharmacological	ADJ
fnp-3528	199	135	drugs	drug	NOUN
fnp-3528	199	136	several	several	ADJ
fnp-3528	199	137	pharmacological	pharmacological	ADJ
fnp-3528	199	138	drugs	drug	NOUN
fnp-3528	199	139	also	also	ADV
fnp-3528	199	140	demonstrated	demonstrate	VERB
fnp-3528	199	141	an	an	DET
fnp-3528	199	142	induction	induction	NOUN
fnp-3528	199	143	of	of	ADP
fnp-3528	199	144	abca1	abca1	NOUN
fnp-3528	199	145	/	/	SYM
fnp-3528	199	146	abca1	abca1	NOUN
fnp-3528	199	147	through	through	ADP
fnp-3528	199	148	lxr	lxr	PROPN
fnp-3528	199	149	-	-	PUNCT
fnp-3528	199	150	α	α	PROPN
fnp-3528	199	151	and/or	and/or	CCONJ
fnp-3528	199	152	lxr	lxr	PROPN
fnp-3528	199	153	-	-	PUNCT
fnp-3528	199	154	β	β	NOUN
fnp-3528	199	155	,	,	PUNCT
fnp-3528	199	156	including	include	VERB
fnp-3528	199	157	the	the	DET
fnp-3528	199	158	α1	α1	NOUN
fnp-3528	199	159	-	-	PUNCT
fnp-3528	199	160	blocker	blocker	NOUN
fnp-3528	199	161	doxazosin,376	doxazosin,376	NOUN
fnp-3528	199	162	the	the	DET
fnp-3528	199	163	5	5	NUM
fnp-3528	199	164	-	-	PUNCT
fnp-3528	199	165	ht3	ht3	NOUN
fnp-3528	199	166	receptor	receptor	NOUN
fnp-3528	199	167	antagonist	antagonist	NOUN
fnp-3528	199	168	ondansetron,279	ondansetron,279	NOUN
fnp-3528	199	169	and	and	CCONJ
fnp-3528	199	170	the	the	DET
fnp-3528	199	171	anesthetic	anesthetic	NOUN
fnp-3528	199	172	propofol.377	propofol.377	NOUN
fnp-3528	199	173	consequently	consequently	ADV
fnp-3528	199	174	,	,	PUNCT
fnp-3528	199	175	increased	increased	ADJ
fnp-3528	199	176	abca1	abca1	NOUN
fnp-3528	199	177	mrna279,376	mrna279,376	NOUN
fnp-3528	199	178	and	and	CCONJ
fnp-3528	199	179	abca1	abca1	PROPN
fnp-3528	199	180	protein279,376	protein279,376	PROPN
fnp-3528	199	181	levels	level	NOUN
fnp-3528	199	182	were	be	AUX
fnp-3528	199	183	observed	observe	VERB
fnp-3528	199	184	in	in	ADP
fnp-3528	199	185	human279,377	human279,377	NOUN
fnp-3528	199	186	and	and	CCONJ
fnp-3528	199	187	murine279,376	murine279,376	PROPN
fnp-3528	199	188	macrophages376,377	macrophages376,377	NOUN
fnp-3528	199	189	as	as	ADV
fnp-3528	199	190	well	well	ADV
fnp-3528	199	191	as	as	ADP
fnp-3528	199	192	astrocytes.279	astrocytes.279	PROPN
fnp-3528	199	193	functionally	functionally	ADV
fnp-3528	199	194	,	,	PUNCT
fnp-3528	199	195	ondansetron	ondansetron	NOUN
fnp-3528	199	196	induced	induce	VERB
fnp-3528	199	197	apoe	apoe	ADP
fnp-3528	199	198	efflux,279	efflux,279	PROPN
fnp-3528	199	199	while	while	SCONJ
fnp-3528	199	200	propofol	propofol	NOUN
fnp-3528	199	201	led	lead	VERB
fnp-3528	199	202	to	to	ADP
fnp-3528	199	203	increased	increase	VERB
fnp-3528	199	204	cholesterol	cholesterol	NOUN
fnp-3528	199	205	efflux.377	efflux.377	NOUN
fnp-3528	199	206	in	in	ADP
fnp-3528	199	207	addition	addition	NOUN
fnp-3528	199	208	,	,	PUNCT
fnp-3528	199	209	propofol	propofol	NOUN
fnp-3528	199	210	increased	increase	VERB
fnp-3528	199	211	pparg	pparg	ADJ
fnp-3528	199	212	mrna	mrna	NOUN
fnp-3528	199	213	and	and	CCONJ
fnp-3528	199	214	ppar	ppar	NOUN
fnp-3528	199	215	-	-	PUNCT
fnp-3528	199	216	γ	γ	NOUN
fnp-3528	199	217	protein	protein	NOUN
fnp-3528	199	218	content	content	NOUN
fnp-3528	199	219	in	in	ADP
fnp-3528	199	220	human	human	ADJ
fnp-3528	199	221	macrophages.377	macrophages.377	NOUN
fnp-3528	199	222	furthermore	furthermore	ADV
fnp-3528	199	223	,	,	PUNCT
fnp-3528	199	224	certain	certain	ADJ
fnp-3528	199	225	antineoplastic	antineoplastic	ADJ
fnp-3528	199	226	agents	agent	NOUN
fnp-3528	199	227	interfered	interfere	VERB
fnp-3528	199	228	with	with	ADP
fnp-3528	199	229	abca1	abca1	NOUN
fnp-3528	199	230	expression	expression	NOUN
fnp-3528	199	231	via	via	ADP
fnp-3528	199	232	lxr	lxr	PROPN
fnp-3528	199	233	-	-	PUNCT
fnp-3528	199	234	α	α	PROPN
fnp-3528	199	235	and/or	and/or	CCONJ
fnp-3528	199	236	lxr	lxr	PROPN
fnp-3528	199	237	-	-	PUNCT
fnp-3528	199	238	β	β	NOUN
fnp-3528	199	239	.	.	PUNCT
fnp-3528	200	1	doxorubicin	doxorubicin	PROPN
fnp-3528	200	2	demonstrated	demonstrate	VERB
fnp-3528	200	3	an	an	DET
fnp-3528	200	4	lxr	lxr	ADJ
fnp-3528	200	5	activation	activation	NOUN
fnp-3528	200	6	with	with	ADP
fnp-3528	200	7	subsequent	subsequent	ADJ
fnp-3528	200	8	induction	induction	NOUN
fnp-3528	200	9	of	of	ADP
fnp-3528	200	10	abca1	abca1	PROPN
fnp-3528	200	11	mrna	mrna	PROPN
fnp-3528	200	12	and	and	CCONJ
fnp-3528	200	13	abca1	abca1	NOUN
fnp-3528	200	14	protein	protein	NOUN
fnp-3528	200	15	in	in	ADP
fnp-3528	200	16	vitro	vitro	X
fnp-3528	200	17	and	and	CCONJ
fnp-3528	200	18	in	in	ADP
fnp-3528	200	19	vivo.250	vivo.250	PROPN
fnp-3528	200	20	functionally	functionally	ADV
fnp-3528	200	21	,	,	PUNCT
fnp-3528	200	22	doxorubicin	doxorubicin	PROPN
fnp-3528	200	23	elevated	elevate	VERB
fnp-3528	200	24	cholesterol	cholesterol	NOUN
fnp-3528	200	25	export	export	NOUN
fnp-3528	200	26	in	in	ADP
fnp-3528	200	27	vitro	vitro	X
fnp-3528	200	28	.	.	PUNCT
fnp-3528	201	1	it	it	PRON
fnp-3528	201	2	was	be	AUX
fnp-3528	201	3	shown	show	VERB
fnp-3528	201	4	that	that	SCONJ
fnp-3528	201	5	intraand	intraand	NOUN
fnp-3528	201	6	extracellular	extracellular	ADJ
fnp-3528	201	7	levels	level	NOUN
fnp-3528	201	8	of	of	ADP
fnp-3528	201	9	cholesterol	cholesterol	NOUN
fnp-3528	201	10	,	,	PUNCT
fnp-3528	201	11	cholesterol	cholesterol	NOUN
fnp-3528	201	12	precursors	precursor	NOUN
fnp-3528	201	13	,	,	PUNCT
fnp-3528	201	14	and	and	CCONJ
fnp-3528	201	15	several	several	ADJ
fnp-3528	201	16	oxysterols	oxysterol	NOUN
fnp-3528	201	17	were	be	AUX
fnp-3528	201	18	elevated	elevate	VERB
fnp-3528	201	19	after	after	ADP
fnp-3528	201	20	exposure	exposure	NOUN
fnp-3528	201	21	to	to	ADP
fnp-3528	201	22	doxorubicin	doxorubicin	PROPN
fnp-3528	201	23	.	.	PUNCT
fnp-3528	202	1	these	these	DET
fnp-3528	202	2	precursors	precursor	NOUN
fnp-3528	202	3	included	include	VERB
fnp-3528	202	4	lathosterol	lathosterol	NOUN
fnp-3528	202	5	,	,	PUNCT
fnp-3528	202	6	lanosterol	lanosterol	NOUN
fnp-3528	202	7	,	,	PUNCT
fnp-3528	202	8	and	and	CCONJ
fnp-3528	202	9	desmosterol	desmosterol	NOUN
fnp-3528	202	10	,	,	PUNCT
fnp-3528	202	11	while	while	SCONJ
fnp-3528	202	12	the	the	DET
fnp-3528	202	13	oxysterols	oxysterol	NOUN
fnp-3528	202	14	included	include	VERB
fnp-3528	202	15	7	7	NUM
fnp-3528	202	16	-	-	PUNCT
fnp-3528	202	17	α	α	DET
fnp-3528	202	18	-	-	PUNCT
fnp-3528	202	19	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	202	20	,	,	PUNCT
fnp-3528	202	21	7	7	NUM
fnp-3528	202	22	-	-	SYM
fnp-3528	202	23	β	β	NOUN
fnp-3528	202	24	-	-	PUNCT
fnp-3528	202	25	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	202	26	,	,	PUNCT
fnp-3528	202	27	7	7	NUM
fnp-3528	202	28	-	-	PUNCT
fnp-3528	202	29	ketocholesterol	ketocholesterol	NOUN
fnp-3528	202	30	,	,	PUNCT
fnp-3528	202	31	24	24	NUM
fnp-3528	202	32	-	-	PUNCT
fnp-3528	202	33	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	202	34	,	,	PUNCT
fnp-3528	202	35	and	and	CCONJ
fnp-3528	202	36	27	27	NUM
fnp-3528	202	37	-	-	PUNCT
fnp-3528	202	38	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	202	39	.	.	PUNCT
fnp-3528	203	1	the	the	DET
fnp-3528	203	2	authors	author	NOUN
fnp-3528	203	3	suggested	suggest	VERB
fnp-3528	203	4	that	that	SCONJ
fnp-3528	203	5	doxorubicin	doxorubicin	PROPN
fnp-3528	203	6	exposure	exposure	NOUN
fnp-3528	203	7	induced	induce	VERB
fnp-3528	203	8	cholesterol	cholesterol	NOUN
fnp-3528	203	9	metabolism	metabolism	NOUN
fnp-3528	203	10	subsequently	subsequently	ADV
fnp-3528	203	11	leading	lead	VERB
fnp-3528	203	12	to	to	ADP
fnp-3528	203	13	an	an	DET
fnp-3528	203	14	induction	induction	NOUN
fnp-3528	203	15	of	of	ADP
fnp-3528	203	16	abca1	abca1	NOUN
fnp-3528	203	17	.	.	PUNCT
fnp-3528	204	1	besides	besides	ADV
fnp-3528	204	2	,	,	PUNCT
fnp-3528	204	3	idarubicin	idarubicin	PROPN
fnp-3528	204	4	augmented	augment	VERB
fnp-3528	204	5	also	also	ADV
fnp-3528	204	6	abca1	abca1	PROPN
fnp-3528	204	7	mrna	mrna	PROPN
fnp-3528	204	8	levels	level	NOUN
fnp-3528	204	9	in	in	ADP
fnp-3528	204	10	vitro	vitro	VERB
fnp-3528	204	11	.	.	PUNCT
fnp-3528	205	1	synthetic	synthetic	ADJ
fnp-3528	205	2	compounds	compound	NOUN
fnp-3528	205	3	and	and	CCONJ
fnp-3528	205	4	hts	hts	PROPN
fnp-3528	205	5	hits	hit	VERB
fnp-3528	205	6	other	other	ADJ
fnp-3528	205	7	synthetic	synthetic	ADJ
fnp-3528	205	8	compounds	compound	NOUN
fnp-3528	205	9	have	have	AUX
fnp-3528	205	10	been	be	AUX
fnp-3528	205	11	shown	show	VERB
fnp-3528	205	12	to	to	PART
fnp-3528	205	13	induce	induce	VERB
fnp-3528	205	14	abca1	abca1	NOUN
fnp-3528	205	15	/	/	SYM
fnp-3528	205	16	abca1	abca1	NOUN
fnp-3528	205	17	expression	expression	NOUN
fnp-3528	205	18	by	by	ADP
fnp-3528	205	19	lxr	lxr	PROPN
fnp-3528	205	20	-	-	PUNCT
fnp-3528	205	21	α	α	PROPN
fnp-3528	205	22	and/or	and/or	CCONJ
fnp-3528	205	23	lxr	lxr	PROPN
fnp-3528	205	24	-	-	PUNCT
fnp-3528	205	25	β	β	NOUN
fnp-3528	205	26	induction	induction	NOUN
fnp-3528	205	27	.	.	PUNCT
fnp-3528	206	1	the	the	DET
fnp-3528	206	2	polymer	polymer	NOUN
fnp-3528	206	3	pyrrole	pyrrole	NOUN
fnp-3528	206	4	-	-	PUNCT
fnp-3528	206	5	imidazole	imidazole	NOUN
fnp-3528	206	6	-	-	PUNCT
fnp-3528	206	7	polyamide	polyamide	NOUN
fnp-3528	206	8	activated	activate	VERB
fnp-3528	206	9	a	a	DET
fnp-3528	206	10	promoter	promoter	NOUN
fnp-3528	206	11	region	region	NOUN
fnp-3528	206	12	for	for	ADP
fnp-3528	206	13	abca1	abca1	NOUN
fnp-3528	206	14	expression	expression	NOUN
fnp-3528	206	15	and	and	CCONJ
fnp-3528	206	16	thereby	thereby	ADV
fnp-3528	206	17	increased	increase	VERB
fnp-3528	206	18	cholesterol	cholesterol	NOUN
fnp-3528	206	19	and	and	CCONJ
fnp-3528	206	20	lipid	lipid	NOUN
fnp-3528	206	21	efflux	efflux	VERB
fnp-3528	206	22	from	from	ADP
fnp-3528	206	23	raw264.7	raw264.7	PROPN
fnp-3528	206	24	cells.376	cells.376	VERB
fnp-3528	206	25	the	the	DET
fnp-3528	206	26	authors	author	NOUN
fnp-3528	206	27	confirmed	confirm	VERB
fnp-3528	206	28	their	their	PRON
fnp-3528	206	29	findings	finding	NOUN
fnp-3528	206	30	in	in	ADP
fnp-3528	206	31	vivo	vivo	NOUN
fnp-3528	206	32	,	,	PUNCT
fnp-3528	206	33	revealing	reveal	VERB
fnp-3528	206	34	increased	increase	VERB
fnp-3528	206	35	abca1	abca1	NOUN
fnp-3528	206	36	mrna	mrna	NOUN
fnp-3528	206	37	and	and	CCONJ
fnp-3528	206	38	abca1	abca1	NOUN
fnp-3528	206	39	protein	protein	NOUN
fnp-3528	206	40	content	content	NOUN
fnp-3528	206	41	in	in	ADP
fnp-3528	206	42	peripheral	peripheral	ADJ
fnp-3528	206	43	blood	blood	NOUN
fnp-3528	206	44	mononuclear	mononuclear	ADJ
fnp-3528	206	45	cells	cell	NOUN
fnp-3528	206	46	and	and	CCONJ
fnp-3528	206	47	the	the	DET
fnp-3528	206	48	liver	liver	NOUN
fnp-3528	206	49	in	in	ADP
fnp-3528	206	50	c57bl/6	c57bl/6	NOUN
fnp-3528	206	51	mice	mouse	NOUN
fnp-3528	206	52	after	after	ADP
fnp-3528	206	53	exposure	exposure	NOUN
fnp-3528	206	54	to	to	ADP
fnp-3528	206	55	pyrrole	pyrrole	NOUN
fnp-3528	206	56	-	-	PUNCT
fnp-3528	206	57	imidazole	imidazole	NOUN
fnp-3528	206	58	-	-	PUNCT
fnp-3528	206	59	polyamide	polyamide	NOUN
fnp-3528	206	60	.	.	PUNCT
fnp-3528	207	1	in	in	ADP
fnp-3528	207	2	addition	addition	NOUN
fnp-3528	207	3	,	,	PUNCT
fnp-3528	207	4	the	the	DET
fnp-3528	207	5	lxr	lxr	NOUN
fnp-3528	207	6	agonist	agonist	NOUN
fnp-3528	207	7	lxr623	lxr623	NOUN
fnp-3528	207	8	induced	induce	VERB
fnp-3528	207	9	abca1	abca1	PROPN
fnp-3528	207	10	mrna	mrna	PROPN
fnp-3528	207	11	and	and	CCONJ
fnp-3528	207	12	abca1	abca1	NOUN
fnp-3528	207	13	protein	protein	NOUN
fnp-3528	207	14	levels	level	NOUN
fnp-3528	207	15	in	in	ADP
fnp-3528	207	16	two	two	NUM
fnp-3528	207	17	human	human	ADJ
fnp-3528	207	18	renal	renal	ADJ
fnp-3528	207	19	adenocarcinoma	adenocarcinoma	NOUN
fnp-3528	207	20	cell	cell	NOUN
fnp-3528	207	21	lines334	lines334	PROPN
fnp-3528	207	22	as	as	ADV
fnp-3528	207	23	well	well	ADV
fnp-3528	207	24	as	as	ADP
fnp-3528	207	25	abca1	abca1	PROPN
fnp-3528	207	26	mrna	mrna	PROPN
fnp-3528	207	27	levels	level	NOUN
fnp-3528	207	28	in	in	ADP
fnp-3528	207	29	vivo	vivo	NOUN
fnp-3528	207	30	in	in	ADP
fnp-3528	207	31	c57bl/6	c57bl/6	NOUN
fnp-3528	207	32	mice.378	mice.378	NOUN
fnp-3528	207	33	this	this	DET
fnp-3528	207	34	induction	induction	NOUN
fnp-3528	207	35	was	be	AUX
fnp-3528	207	36	reflected	reflect	VERB
fnp-3528	207	37	in	in	ADP
fnp-3528	207	38	reduced	reduced	ADJ
fnp-3528	207	39	intracellular	intracellular	ADJ
fnp-3528	207	40	cholesterol	cholesterol	NOUN
fnp-3528	207	41	and	and	CCONJ
fnp-3528	207	42	triglyceride	triglyceride	ADJ
fnp-3528	207	43	levels	level	NOUN
fnp-3528	207	44	.	.	PUNCT
fnp-3528	208	1	it	it	PRON
fnp-3528	208	2	must	must	AUX
fnp-3528	208	3	be	be	AUX
fnp-3528	208	4	noted	note	VERB
fnp-3528	208	5	that	that	SCONJ
fnp-3528	208	6	several	several	ADJ
fnp-3528	208	7	other	other	ADJ
fnp-3528	208	8	synthetic	synthetic	ADJ
fnp-3528	208	9	lxr	lxr	NOUN
fnp-3528	208	10	-	-	PUNCT
fnp-3528	208	11	α	α	PROPN
fnp-3528	208	12	and	and	CCONJ
fnp-3528	208	13	lxr	lxr	PROPN
fnp-3528	208	14	-	-	PUNCT
fnp-3528	208	15	β	β	NOUN
fnp-3528	208	16	agonists	agonist	NOUN
fnp-3528	208	17	induced	induce	VERB
fnp-3528	208	18	abca1	abca1	NOUN
fnp-3528	208	19	expression	expression	NOUN
fnp-3528	208	20	in	in	ADP
fnp-3528	208	21	vivo	vivo	NOUN
fnp-3528	208	22	:	:	PUNCT
fnp-3528	208	23	az1	az1	NOUN
fnp-3528	208	24	–	–	PUNCT
fnp-3528	208	25	az9	az9	NOUN
fnp-3528	208	26	,	,	PUNCT
fnp-3528	208	27	az876	az876	NOUN
fnp-3528	208	28	,	,	PUNCT
fnp-3528	208	29	bms-852927	bms-852927	NOUN
fnp-3528	208	30	,	,	PUNCT
fnp-3528	208	31	f1	f1	NOUN
fnp-3528	208	32	,	,	PUNCT
fnp-3528	208	33	way254011.378	way254011.378	PROPN
fnp-3528	208	34	finally	finally	ADV
fnp-3528	208	35	,	,	PUNCT
fnp-3528	208	36	an	an	DET
fnp-3528	208	37	hts	hts	PROPN
fnp-3528	208	38	approach	approach	NOUN
fnp-3528	208	39	discovered	discover	VERB
fnp-3528	208	40	two	two	NUM
fnp-3528	208	41	lxr	lxr	NOUN
fnp-3528	208	42	-	-	PUNCT
fnp-3528	208	43	α	α	NOUN
fnp-3528	208	44	and	and	CCONJ
fnp-3528	208	45	lxr	lxr	PROPN
fnp-3528	208	46	-	-	PUNCT
fnp-3528	208	47	β	β	NOUN
fnp-3528	208	48	agonists	agonist	NOUN
fnp-3528	208	49	as	as	SCONJ
fnp-3528	208	50	novel	novel	ADJ
fnp-3528	208	51	small	small	ADJ
fnp-3528	208	52	-	-	PUNCT
fnp-3528	208	53	molecule	molecule	NOUN
fnp-3528	208	54	abca1	abca1	NOUN
fnp-3528	208	55	/	/	SYM
fnp-3528	208	56	abca1	abca1	NOUN
fnp-3528	208	57	inducers	inducer	NOUN
fnp-3528	208	58	:	:	PUNCT
fnp-3528	208	59	f4	f4	ADJ
fnp-3528	208	60	and	and	CCONJ
fnp-3528	208	61	m2.319	m2.319	PROPN
fnp-3528	208	62	synthetic	synthetic	NOUN
fnp-3528	208	63	approaches	approach	VERB
fnp-3528	208	64	a	a	DET
fnp-3528	208	65	few	few	ADJ
fnp-3528	208	66	synthetic	synthetic	ADJ
fnp-3528	208	67	approaches	approach	NOUN
fnp-3528	208	68	have	have	AUX
fnp-3528	208	69	aimed	aim	VERB
fnp-3528	208	70	toward	toward	ADP
fnp-3528	208	71	the	the	DET
fnp-3528	208	72	development	development	NOUN
fnp-3528	208	73	of	of	ADP
fnp-3528	208	74	abca1	abca1	NOUN
fnp-3528	208	75	/	/	SYM
fnp-3528	208	76	abca1	abca1	NOUN
fnp-3528	208	77	inducers.271,336,352,379	inducers.271,336,352,379	PROPN
fnp-3528	208	78	-	-	PUNCT
fnp-3528	208	79	382	382	NUM
fnp-3528	208	80	the	the	DET
fnp-3528	208	81	cholic	cholic	ADJ
fnp-3528	208	82	acid	acid	NOUN
fnp-3528	208	83	analog	analog	NOUN
fnp-3528	208	84	14b,336	14b,336	NUM
fnp-3528	208	85	the	the	DET
fnp-3528	208	86	thiophene	thiophene	NOUN
fnp-3528	208	87	derivative	derivative	ADJ
fnp-3528	208	88	cl2	cl2	NOUN
fnp-3528	208	89	-	-	PUNCT
fnp-3528	208	90	57,271	57,271	NUM
fnp-3528	208	91	as	as	ADV
fnp-3528	208	92	well	well	ADV
fnp-3528	208	93	as	as	ADP
fnp-3528	208	94	derivatives	derivative	NOUN
fnp-3528	208	95	of	of	ADP
fnp-3528	208	96	n	n	CCONJ
fnp-3528	208	97	-	-	PUNCT
fnp-3528	208	98	benzothiazolyl-2	benzothiazolyl-2	VERB
fnp-3528	208	99	-	-	PUNCT
fnp-3528	208	100	benzene	benzene	NOUN
fnp-3528	208	101	-	-	PUNCT
fnp-3528	208	102	sulfonamide,379	sulfonamide,379	PROPN
fnp-3528	208	103	ginsenoside,352	ginsenoside,352	PROPN
fnp-3528	208	104	and	and	CCONJ
fnp-3528	208	105	rutaecarpine,367	rutaecarpine,367	PROPN
fnp-3528	208	106	all	all	PRON
fnp-3528	208	107	induced	induced	ADJ
fnp-3528	208	108	abca1	abca1	NOUN
fnp-3528	208	109	/	/	SYM
fnp-3528	208	110	abca1	abca1	NOUN
fnp-3528	208	111	mrna336,352,381	mrna336,352,381	NUM
fnp-3528	208	112	and	and	CCONJ
fnp-3528	208	113	abca1	abca1	NOUN
fnp-3528	208	114	protein271,336,379,381	protein271,336,379,381	NOUN
fnp-3528	208	115	content	content	NOUN
fnp-3528	208	116	in	in	ADP
fnp-3528	208	117	vitro271,336,379	vitro271,336,379	PROPN
fnp-3528	208	118	and	and	CCONJ
fnp-3528	208	119	in	in	ADP
fnp-3528	208	120	vivo,271	vivo,271	NOUN
fnp-3528	208	121	targeting	target	VERB
fnp-3528	208	122	the	the	DET
fnp-3528	208	123	lxr	lxr	NOUN
fnp-3528	208	124	-	-	PUNCT
fnp-3528	208	125	α	α	NOUN
fnp-3528	208	126	/	/	SYM
fnp-3528	208	127	lxr	lxr	PROPN
fnp-3528	208	128	-	-	PUNCT
fnp-3528	208	129	β	β	X
fnp-3528	208	130	pathway352	pathway352	NOUN
fnp-3528	208	131	by	by	ADP
fnp-3528	208	132	activation271	activation271	PROPN
fnp-3528	208	133	or	or	CCONJ
fnp-3528	208	134	induction336	induction336	PROPN
fnp-3528	208	135	of	of	ADP
fnp-3528	208	136	lxr	lxr	PROPN
fnp-3528	208	137	-	-	PUNCT
fnp-3528	208	138	α	α	NOUN
fnp-3528	208	139	/	/	SYM
fnp-3528	208	140	lxra	lxra	NOUN
fnp-3528	208	141	/	/	SYM
fnp-3528	208	142	lxra	lxra	NOUN
fnp-3528	208	143	and/or	and/or	CCONJ
fnp-3528	208	144	lxr	lxr	PROPN
fnp-3528	208	145	-	-	PUNCT
fnp-3528	208	146	β	β	NOUN
fnp-3528	208	147	/	/	SYM
fnp-3528	208	148	lxrb	lxrb	NOUN
fnp-3528	208	149	/	/	SYM
fnp-3528	208	150	lxrb	lxrb	NOUN
fnp-3528	208	151	.	.	PUNCT
fnp-3528	209	1	in	in	ADP
fnp-3528	209	2	vitro	vitro	X
fnp-3528	209	3	,	,	PUNCT
fnp-3528	209	4	cholesterol	cholesterol	NOUN
fnp-3528	209	5	efflux	efflux	NOUN
fnp-3528	209	6	increased379,381	increased379,381	NOUN
fnp-3528	209	7	and	and	CCONJ
fnp-3528	209	8	intracellular	intracellular	ADJ
fnp-3528	209	9	cholesterol	cholesterol	NOUN
fnp-3528	209	10	as	as	ADV
fnp-3528	209	11	well	well	ADV
fnp-3528	209	12	as	as	ADP
fnp-3528	209	13	lipid	lipid	NOUN
fnp-3528	209	14	content	content	NOUN
fnp-3528	209	15	were	be	AUX
fnp-3528	209	16	reduced,336,352	reduced,336,352	VERB
fnp-3528	209	17	while	while	SCONJ
fnp-3528	209	18	plasma	plasma	NOUN
fnp-3528	209	19	and	and	CCONJ
fnp-3528	209	20	liver	liver	NOUN
fnp-3528	209	21	triglycerides	triglyceride	NOUN
fnp-3528	209	22	levels	level	NOUN
fnp-3528	209	23	were	be	AUX
fnp-3528	209	24	reduced	reduce	VERB
fnp-3528	209	25	in	in	ADP
fnp-3528	209	26	vivo	vivo	NOUN
fnp-3528	209	27	in	in	ADP
fnp-3528	209	28	high	high	ADJ
fnp-3528	209	29	fat	fat	ADJ
fnp-3528	209	30	diet	diet	NOUN
fnp-3528	209	31	-	-	PUNCT
fnp-3528	209	32	fed	feed	VERB
fnp-3528	209	33	c57bl/6	c57bl/6	NOUN
fnp-3528	209	34	mice.271	mice.271	NOUN
fnp-3528	209	35	interestingly	interestingly	ADV
fnp-3528	209	36	,	,	PUNCT
fnp-3528	209	37	14b	14b	X
fnp-3528	209	38	induced	induce	VERB
fnp-3528	209	39	farnesoid	farnesoid	ADJ
fnp-3528	209	40	-	-	PUNCT
fnp-3528	209	41	x	x	NOUN
fnp-3528	209	42	-	-	NOUN
fnp-3528	209	43	receptor	receptor	NOUN
fnp-3528	209	44	(	(	PUNCT
fnp-3528	209	45	fxr	fxr	NOUN
fnp-3528	209	46	)	)	PUNCT
fnp-3528	209	47	transcription	transcription	NOUN
fnp-3528	209	48	(	(	PUNCT
fnp-3528	209	49	fxr),336	fxr),336	NOUN
fnp-3528	209	50	and	and	CCONJ
fnp-3528	209	51	cl2	cl2	PROPN
fnp-3528	209	52	-	-	ADJ
fnp-3528	209	53	57	57	NUM
fnp-3528	209	54	inhibited	inhibited	ADJ
fnp-3528	209	55	rxr	rxr	NOUN
fnp-3528	209	56	-	-	PUNCT
fnp-3528	209	57	β	β	PROPN
fnp-3528	209	58	,	,	PUNCT
fnp-3528	209	59	ppar	ppar	NOUN
fnp-3528	209	60	-	-	PUNCT
fnp-3528	209	61	γ	γ	NOUN
fnp-3528	209	62	,	,	PUNCT
fnp-3528	209	63	and	and	CCONJ
fnp-3528	209	64	ppar	ppar	NOUN
fnp-3528	209	65	-	-	PUNCT
fnp-3528	209	66	δ,271	δ,271	NOUN
fnp-3528	209	67	finally	finally	ADV
fnp-3528	209	68	,	,	PUNCT
fnp-3528	209	69	singh	singh	PROPN
fnp-3528	209	70	et	et	PROPN
fnp-3528	209	71	al	al	PROPN
fnp-3528	209	72	.	.	PROPN
fnp-3528	209	73	described	describe	VERB
fnp-3528	209	74	highly	highly	ADV
fnp-3528	209	75	potent	potent	ADJ
fnp-3528	209	76	lxr	lxr	NOUN
fnp-3528	209	77	-	-	PUNCT
fnp-3528	209	78	α	α	PROPN
fnp-3528	209	79	and	and	CCONJ
fnp-3528	209	80	lxr	lxr	PROPN
fnp-3528	209	81	-	-	PUNCT
fnp-3528	209	82	β	β	NOUN
fnp-3528	209	83	agonists	agonist	NOUN
fnp-3528	209	84	with	with	ADP
fnp-3528	209	85	effect	effect	NOUN
fnp-3528	209	86	at	at	ADP
fnp-3528	209	87	concentrations	concentration	NOUN
fnp-3528	209	88	in	in	ADP
fnp-3528	209	89	the	the	DET
fnp-3528	209	90	nanomolar	nanomolar	ADJ
fnp-3528	209	91	range.382	range.382	NOUN
fnp-3528	209	92	the	the	DET
fnp-3528	209	93	described	describe	VERB
fnp-3528	209	94	podocarpic	podocarpic	NOUN
fnp-3528	209	95	acid	acid	NOUN
fnp-3528	209	96	derivatives	derivative	NOUN
fnp-3528	209	97	have	have	AUX
fnp-3528	209	98	not	not	PART
fnp-3528	209	99	yet	yet	ADV
fnp-3528	209	100	been	be	AUX
fnp-3528	209	101	demonstrated	demonstrate	VERB
fnp-3528	209	102	to	to	PART
fnp-3528	209	103	induce	induce	VERB
fnp-3528	209	104	abca1	abca1	NOUN
fnp-3528	209	105	.	.	PUNCT
fnp-3528	210	1	however	however	ADV
fnp-3528	210	2	,	,	PUNCT
fnp-3528	210	3	these	these	DET
fnp-3528	210	4	compounds	compound	NOUN
fnp-3528	210	5	were	be	AUX
fnp-3528	210	6	designated	designate	VERB
fnp-3528	210	7	as	as	ADP
fnp-3528	210	8	potential	potential	ADJ
fnp-3528	210	9	abca1	abca1	NOUN
fnp-3528	210	10	inducers	inducer	NOUN
fnp-3528	210	11	by	by	ADP
fnp-3528	210	12	the	the	DET
fnp-3528	210	13	authors,382	authors,382	PROPN
fnp-3528	210	14	and	and	CCONJ
fnp-3528	210	15	their	their	PRON
fnp-3528	210	16	high	high	ADJ
fnp-3528	210	17	potency	potency	NOUN
fnp-3528	210	18	makes	make	VERB
fnp-3528	210	19	them	they	PRON
fnp-3528	210	20	interesting	interesting	ADJ
fnp-3528	210	21	candidates	candidate	NOUN
fnp-3528	210	22	for	for	ADP
fnp-3528	210	23	further	further	ADJ
fnp-3528	210	24	evaluation	evaluation	NOUN
fnp-3528	210	25	.	.	PUNCT
fnp-3528	211	1	such	such	ADJ
fnp-3528	211	2	synthetic	synthetic	ADJ
fnp-3528	211	3	approaches	approach	NOUN
fnp-3528	211	4	should	should	AUX
fnp-3528	211	5	be	be	AUX
fnp-3528	211	6	highlighted,271,336,352,379	highlighted,271,336,352,379	NOUN
fnp-3528	211	7	-	-	PUNCT
fnp-3528	211	8	382	382	NUM
fnp-3528	211	9	as	as	ADP
fnp-3528	211	10	chemical	chemical	ADJ
fnp-3528	211	11	derivatization	derivatization	NOUN
fnp-3528	211	12	of	of	ADP
fnp-3528	211	13	abca1	abca1	NOUN
fnp-3528	211	14	inducers	inducer	NOUN
fnp-3528	211	15	and	and	CCONJ
fnp-3528	211	16	elucidation	elucidation	NOUN
fnp-3528	211	17	of	of	ADP
fnp-3528	211	18	their	their	PRON
fnp-3528	211	19	structure	structure	NOUN
fnp-3528	211	20	-	-	PUNCT
fnp-3528	211	21	activity	activity	NOUN
fnp-3528	211	22	relationships	relationship	NOUN
fnp-3528	211	23	(	(	PUNCT
fnp-3528	211	24	sar	sar	NOUN
fnp-3528	211	25	)	)	PUNCT
fnp-3528	211	26	have	have	AUX
fnp-3528	211	27	not	not	PART
fnp-3528	211	28	yet	yet	ADV
fnp-3528	211	29	been	be	AUX
fnp-3528	211	30	comprehensively	comprehensively	ADV
fnp-3528	211	31	assessed	assess	VERB
fnp-3528	211	32	.	.	PUNCT
fnp-3528	212	1	more	more	ADJ
fnp-3528	212	2	reports	report	NOUN
fnp-3528	212	3	are	be	AUX
fnp-3528	212	4	needed	need	VERB
fnp-3528	212	5	to	to	PART
fnp-3528	212	6	gain	gain	VERB
fnp-3528	212	7	innovative	innovative	ADJ
fnp-3528	212	8	molecules	molecule	NOUN
fnp-3528	212	9	that	that	PRON
fnp-3528	212	10	can	can	AUX
fnp-3528	212	11	be	be	AUX
fnp-3528	212	12	considered	consider	VERB
fnp-3528	212	13	clinically	clinically	ADV
fnp-3528	212	14	for	for	ADP
fnp-3528	212	15	the	the	DET
fnp-3528	212	16	treatment	treatment	NOUN
fnp-3528	212	17	of	of	ADP
fnp-3528	212	18	various	various	ADJ
fnp-3528	212	19	abca1	abca1	NOUN
fnp-3528	212	20	-	-	PUNCT
fnp-3528	212	21	related	relate	VERB
fnp-3528	212	22	diseases	disease	NOUN
fnp-3528	212	23	.	.	PUNCT
fnp-3528	213	1	abca1	abca1	PROPN
fnp-3528	213	2	other	other	ADJ
fnp-3528	213	3	rxr	rxr	PROPN
fnp-3528	213	4	agonists	agonist	NOUN
fnp-3528	213	5	and	and	CCONJ
fnp-3528	213	6	inducers	inducer	NOUN
fnp-3528	213	7	in	in	ADP
fnp-3528	213	8	terms	term	NOUN
fnp-3528	213	9	of	of	ADP
fnp-3528	213	10	synthetic	synthetic	ADJ
fnp-3528	213	11	rxr	rxr	NOUN
fnp-3528	213	12	agonists	agonist	NOUN
fnp-3528	213	13	,	,	PUNCT
fnp-3528	213	14	the	the	DET
fnp-3528	213	15	4	4	NUM
fnp-3528	213	16	-	-	PUNCT
fnp-3528	213	17	chromanon	chromanon	NOUN
fnp-3528	213	18	derivatives	derivative	NOUN
fnp-3528	213	19	spf1	spf1	PROPN
fnp-3528	213	20	and	and	CCONJ
fnp-3528	213	21	spf2	spf2	PROPN
fnp-3528	213	22	increased	increase	VERB
fnp-3528	213	23	abcb1	abcb1	PROPN
fnp-3528	213	24	mrna	mrna	PROPN
fnp-3528	213	25	and	and	CCONJ
fnp-3528	213	26	abca1	abca1	NOUN
fnp-3528	213	27	protein	protein	NOUN
fnp-3528	213	28	levels	level	NOUN
fnp-3528	213	29	and	and	CCONJ
fnp-3528	213	30	lowered	lower	VERB
fnp-3528	213	31	aβ25–35	aβ25–35	ADV
fnp-3528	213	32	-	-	PUNCT
fnp-3528	213	33	mediated	mediate	VERB
fnp-3528	213	34	cell	cell	NOUN
fnp-3528	213	35	toxicity	toxicity	NOUN
fnp-3528	213	36	in	in	ADP
fnp-3528	213	37	vitro.280	vitro.280	NOUN
fnp-3528	213	38	the	the	DET
fnp-3528	213	39	same	same	ADJ
fnp-3528	213	40	effect	effect	NOUN
fnp-3528	213	41	was	be	AUX
fnp-3528	213	42	observed	observe	VERB
fnp-3528	213	43	for	for	ADP
fnp-3528	213	44	the	the	DET
fnp-3528	213	45	rxr	rxr	PROPN
fnp-3528	213	46	agonist	agonist	PROPN
fnp-3528	213	47	bexarotene,280	bexarotene,280	NOUN
fnp-3528	213	48	an	an	DET
fnp-3528	213	49	fda	fda	PROPN
fnp-3528	213	50	approved	approve	VERB
fnp-3528	213	51	drug	drug	NOUN
fnp-3528	213	52	against	against	ADP
fnp-3528	213	53	t	t	NOUN
fnp-3528	213	54	-	-	PUNCT
fnp-3528	213	55	cell	cell	NOUN
fnp-3528	213	56	lymphoma	lymphoma	NOUN
fnp-3528	213	57	-	-	PUNCT
fnp-3528	213	58	related	relate	VERB
fnp-3528	213	59	cutaneous	cutaneous	ADJ
fnp-3528	213	60	malformations	malformation	NOUN
fnp-3528	213	61	.	.	PUNCT
fnp-3528	214	1	bexarotene	bexarotene	NOUN
fnp-3528	214	2	was	be	AUX
fnp-3528	214	3	used	use	VERB
fnp-3528	214	4	as	as	ADP
fnp-3528	214	5	a	a	DET
fnp-3528	214	6	standard	standard	ADJ
fnp-3528	214	7	inducer	inducer	NOUN
fnp-3528	214	8	of	of	ADP
fnp-3528	214	9	abca1	abca1	NOUN
fnp-3528	214	10	/	/	SYM
fnp-3528	214	11	abca1	abca1	NOUN
fnp-3528	214	12	via	via	ADP
fnp-3528	214	13	the	the	DET
fnp-3528	214	14	rxr	rxr	PROPN
fnp-3528	214	15	pathway	pathway	NOUN
fnp-3528	214	16	in	in	ADP
fnp-3528	214	17	several	several	ADJ
fnp-3528	214	18	studies.271,272,280,319,380	studies.271,272,280,319,380	ADJ
fnp-3528	214	19	induction	induction	NOUN
fnp-3528	214	20	of	of	ADP
fnp-3528	214	21	abca1	abca1	PROPN
fnp-3528	214	22	mrna	mrna	PROPN
fnp-3528	214	23	and	and	CCONJ
fnp-3528	214	24	abca1	abca1	NOUN
fnp-3528	214	25	protein	protein	NOUN
fnp-3528	214	26	levels	level	NOUN
fnp-3528	214	27	was	be	AUX
fnp-3528	214	28	maximal	maximal	ADJ
fnp-3528	214	29	for	for	SCONJ
fnp-3528	214	30	bexarotene	bexarotene	NOUN
fnp-3528	214	31	in	in	ADP
fnp-3528	214	32	combination	combination	NOUN
fnp-3528	214	33	with	with	ADP
fnp-3528	214	34	to901317.280	to901317.280	NOUN
fnp-3528	214	35	bexarotene	bexarotene	NOUN
fnp-3528	214	36	is	be	AUX
fnp-3528	214	37	of	of	ADP
fnp-3528	214	38	particular	particular	ADJ
fnp-3528	214	39	practical	practical	ADJ
fnp-3528	214	40	relevance	relevance	NOUN
fnp-3528	214	41	as	as	ADP
fnp-3528	214	42	a	a	DET
fnp-3528	214	43	potential	potential	ADJ
fnp-3528	214	44	treatment	treatment	NOUN
fnp-3528	214	45	against	against	ADP
fnp-3528	214	46	ad	ad	NOUN
fnp-3528	214	47	due	due	ADP
fnp-3528	214	48	to	to	ADP
fnp-3528	214	49	its	its	PRON
fnp-3528	214	50	in	in	ADP
fnp-3528	214	51	vivo	vivo	ADJ
fnp-3528	214	52	effects	effect	NOUN
fnp-3528	214	53	.	.	PUNCT
fnp-3528	215	1	in	in	ADP
fnp-3528	215	2	different	different	ADJ
fnp-3528	215	3	ad	ad	NOUN
fnp-3528	215	4	mouse	mouse	NOUN
fnp-3528	215	5	models	model	NOUN
fnp-3528	215	6	,	,	PUNCT
fnp-3528	215	7	bexarotene	bexarotene	NOUN
fnp-3528	215	8	increased	increase	VERB
fnp-3528	215	9	abca1	abca1	PROPN
fnp-3528	215	10	mrna	mrna	PROPN
fnp-3528	215	11	and	and	CCONJ
fnp-3528	215	12	abca1	abca1	NOUN
fnp-3528	215	13	protein	protein	NOUN
fnp-3528	215	14	levels	level	NOUN
fnp-3528	215	15	,	,	PUNCT
fnp-3528	215	16	but	but	CCONJ
fnp-3528	215	17	also	also	ADV
fnp-3528	215	18	reduced	reduce	VERB
fnp-3528	215	19	cerebral	cerebral	ADJ
fnp-3528	215	20	load	load	NOUN
fnp-3528	215	21	of	of	ADP
fnp-3528	215	22	aβ	aβ	NOUN
fnp-3528	215	23	and	and	CCONJ
fnp-3528	215	24	hyperphosphorylated	hyperphosphorylate	VERB
fnp-3528	215	25	protein	protein	NOUN
fnp-3528	215	26	tau	tau	PROPN
fnp-3528	215	27	,	,	PUNCT
fnp-3528	215	28	which	which	PRON
fnp-3528	215	29	is	be	AUX
fnp-3528	215	30	also	also	ADV
fnp-3528	215	31	a	a	DET
fnp-3528	215	32	histological	histological	ADJ
fnp-3528	215	33	marker	marker	NOUN
fnp-3528	215	34	in	in	ADP
fnp-3528	215	35	ad	ad	NOUN
fnp-3528	215	36	and	and	CCONJ
fnp-3528	215	37	other	other	ADJ
fnp-3528	215	38	dementias.297,383	dementias.297,383	NOUN
fnp-3528	215	39	this	this	DET
fnp-3528	215	40	prospect	prospect	NOUN
fnp-3528	215	41	led	lead	VERB
fnp-3528	215	42	to	to	ADP
fnp-3528	215	43	synthetic	synthetic	ADJ
fnp-3528	215	44	bexarotene	bexarotene	NOUN
fnp-3528	215	45	derivatives	derivative	NOUN
fnp-3528	215	46	,	,	PUNCT
fnp-3528	215	47	specifically	specifically	ADV
fnp-3528	215	48	z10	z10	NOUN
fnp-3528	215	49	and	and	CCONJ
fnp-3528	215	50	z36.380	z36.380	PROPN
fnp-3528	215	51	both	both	DET
fnp-3528	215	52	candidates	candidate	NOUN
fnp-3528	215	53	induced	induce	VERB
fnp-3528	215	54	abca1	abca1	NOUN
fnp-3528	215	55	protein	protein	NOUN
fnp-3528	215	56	expression	expression	NOUN
fnp-3528	215	57	by	by	ADP
fnp-3528	215	58	rxr	rxr	PROPN
fnp-3528	215	59	-	-	PUNCT
fnp-3528	215	60	α	α	NOUN
fnp-3528	215	61	activation	activation	NOUN
fnp-3528	215	62	and	and	CCONJ
fnp-3528	215	63	reduced	reduce	VERB
fnp-3528	215	64	aβ	aβ	PRON
fnp-3528	215	65	burden	burden	NOUN
fnp-3528	215	66	in	in	ADP
fnp-3528	215	67	the	the	DET
fnp-3528	215	68	hippocampus	hippocampus	NOUN
fnp-3528	215	69	of	of	ADP
fnp-3528	215	70	female	female	ADJ
fnp-3528	215	71	app	app	PROPN
fnp-3528	215	72	/	/	SYM
fnp-3528	215	73	ps1	ps1	NOUN
fnp-3528	215	74	mice	mouse	NOUN
fnp-3528	215	75	.	.	PUNCT
fnp-3528	216	1	this	this	PRON
fnp-3528	216	2	coincided	coincide	VERB
fnp-3528	216	3	with	with	ADP
fnp-3528	216	4	an	an	DET
fnp-3528	216	5	enhanced	enhanced	ADJ
fnp-3528	216	6	abca1	abca1	NOUN
fnp-3528	216	7	protein	protein	NOUN
fnp-3528	216	8	expression	expression	NOUN
fnp-3528	216	9	in	in	ADP
fnp-3528	216	10	bv2	bv2	NOUN
fnp-3528	216	11	cells	cell	NOUN
fnp-3528	216	12	.	.	PUNCT
fnp-3528	217	1	moreover	moreover	ADV
fnp-3528	217	2	,	,	PUNCT
fnp-3528	217	3	the	the	DET
fnp-3528	217	4	pan	pan	NOUN
fnp-3528	217	5	-	-	ADJ
fnp-3528	217	6	rar	rar	NOUN
fnp-3528	217	7	agonist	agonist	NOUN
fnp-3528	217	8	ttnpb	ttnpb	NOUN
fnp-3528	217	9	also	also	ADV
fnp-3528	217	10	increased	increase	VERB
fnp-3528	217	11	abca1	abca1	NOUN
fnp-3528	217	12	protein	protein	NOUN
fnp-3528	217	13	content	content	NOUN
fnp-3528	217	14	in	in	ADP
fnp-3528	217	15	murine	murine	ADJ
fnp-3528	217	16	macrophages	macrophage	NOUN
fnp-3528	217	17	in	in	ADP
fnp-3528	217	18	an	an	DET
fnp-3528	217	19	rxr	rxr	PROPN
fnp-3528	217	20	-	-	PUNCT
fnp-3528	217	21	α	α	NOUN
fnp-3528	217	22	-	-	PUNCT
fnp-3528	217	23	dependent	dependent	ADJ
fnp-3528	217	24	manner	manner	NOUN
fnp-3528	217	25	.	.	PUNCT
fnp-3528	218	1	however	however	ADV
fnp-3528	218	2	,	,	PUNCT
fnp-3528	218	3	the	the	DET
fnp-3528	218	4	effect	effect	NOUN
fnp-3528	218	5	was	be	AUX
fnp-3528	218	6	generally	generally	ADV
fnp-3528	218	7	smaller	small	ADJ
fnp-3528	218	8	compared	compare	VERB
fnp-3528	218	9	to	to	ADP
fnp-3528	218	10	the	the	DET
fnp-3528	218	11	effect	effect	NOUN
fnp-3528	218	12	of	of	ADP
fnp-3528	218	13	atra.329	atra.329	PROPN
fnp-3528	218	14	finally	finally	ADV
fnp-3528	218	15	,	,	PUNCT
fnp-3528	218	16	a	a	DET
fnp-3528	218	17	combination	combination	NOUN
fnp-3528	218	18	of	of	ADP
fnp-3528	218	19	the	the	DET
fnp-3528	218	20	lxr	lxr	NOUN
fnp-3528	218	21	and	and	CCONJ
fnp-3528	218	22	rxr	rxr	PROPN
fnp-3528	218	23	agonists	agonist	NOUN
fnp-3528	218	24	ro0721957	ro0721957	NOUN
fnp-3528	218	25	and	and	CCONJ
fnp-3528	218	26	ro0264456	ro0264456	NOUN
fnp-3528	218	27	increased	increase	VERB
fnp-3528	218	28	abca1	abca1	PROPN
fnp-3528	218	29	mrna	mrna	PROPN
fnp-3528	218	30	in	in	ADP
fnp-3528	218	31	thp-1	thp-1	ADP
fnp-3528	218	32	macrophages	macrophage	NOUN
fnp-3528	218	33	accompanied	accompany	VERB
fnp-3528	218	34	by	by	ADP
fnp-3528	218	35	increased	increase	VERB
fnp-3528	218	36	cholesterol	cholesterol	NOUN
fnp-3528	218	37	efflux.384	efflux.384	PROPN
fnp-3528	218	38	ro0264456	ro0264456	NOUN
fnp-3528	218	39	was	be	AUX
fnp-3528	218	40	demonstrated	demonstrate	VERB
fnp-3528	218	41	to	to	PART
fnp-3528	218	42	increase	increase	VERB
fnp-3528	218	43	abca1	abca1	NOUN
fnp-3528	218	44	protein	protein	NOUN
fnp-3528	218	45	content	content	NOUN
fnp-3528	218	46	in	in	ADP
fnp-3528	218	47	combination	combination	NOUN
fnp-3528	218	48	with	with	ADP
fnp-3528	218	49	to901317.260	to901317.260	ADJ
fnp-3528	218	50	abca1	abca1	NOUN
fnp-3528	218	51	–	–	PUNCT
fnp-3528	218	52	protein	protein	NOUN
fnp-3528	218	53	kinase	kinase	NOUN
fnp-3528	218	54	c	c	PROPN
fnp-3528	218	55	(	(	PUNCT
fnp-3528	218	56	pkc	pkc	PROPN
fnp-3528	218	57	)	)	PUNCT
fnp-3528	218	58	,	,	PUNCT
fnp-3528	218	59	ampk	ampk	NOUN
fnp-3528	218	60	,	,	PUNCT
fnp-3528	218	61	and	and	CCONJ
fnp-3528	218	62	p38	p38	NOUN
fnp-3528	218	63	mitogen	mitogen	NOUN
fnp-3528	218	64	-	-	PUNCT
fnp-3528	218	65	activated	activate	VERB
fnp-3528	218	66	protein	protein	NOUN
fnp-3528	218	67	kinase	kinase	NOUN
fnp-3528	218	68	(	(	PUNCT
fnp-3528	218	69	mapk	mapk	NOUN
fnp-3528	218	70	)	)	PUNCT
fnp-3528	218	71	an	an	DET
fnp-3528	218	72	alternative	alternative	ADJ
fnp-3528	218	73	approach	approach	NOUN
fnp-3528	218	74	to	to	PART
fnp-3528	218	75	induce	induce	VERB
fnp-3528	218	76	abca1	abca1	NOUN
fnp-3528	218	77	is	be	AUX
fnp-3528	218	78	targeting	target	VERB
fnp-3528	218	79	the	the	DET
fnp-3528	218	80	pkc	pkc	NOUN
fnp-3528	218	81	pathway	pathway	NOUN
fnp-3528	218	82	(	(	PUNCT
fnp-3528	218	83	figure	figure	NOUN
fnp-3528	218	84	 	 	SPACE
fnp-3528	218	85	3	3	NUM
fnp-3528	218	86	)	)	PUNCT
fnp-3528	218	87	.	.	PUNCT
fnp-3528	219	1	pkc	pkc	PROPN
fnp-3528	219	2	agonists	agonist	NOUN
fnp-3528	219	3	were	be	AUX
fnp-3528	219	4	extensively	extensively	ADV
fnp-3528	219	5	used	use	VERB
fnp-3528	219	6	to	to	PART
fnp-3528	219	7	induce	induce	VERB
fnp-3528	219	8	abca1	abca1	NOUN
fnp-3528	219	9	/	/	SYM
fnp-3528	219	10	abca1	abca1	NOUN
fnp-3528	219	11	mrna	mrna	NOUN
fnp-3528	219	12	and	and	CCONJ
fnp-3528	219	13	abca1	abca1	NOUN
fnp-3528	219	14	protein	protein	NOUN
fnp-3528	219	15	levels.230,248,249,255,265,266,273,278,289	levels.230,248,249,255,265,266,273,278,289	PROPN
fnp-3528	219	16	-	-	PUNCT
fnp-3528	219	17	292,384	292,384	NUM
fnp-3528	219	18	-	-	SYM
fnp-3528	219	19	387	387	NUM
fnp-3528	219	20	prominent	prominent	ADJ
fnp-3528	219	21	pkc	pkc	NOUN
fnp-3528	219	22	agonists	agonist	NOUN
fnp-3528	219	23	include	include	VERB
fnp-3528	219	24	camp313	camp313	PROPN
fnp-3528	219	25	as	as	ADV
fnp-3528	219	26	well	well	ADV
fnp-3528	219	27	as	as	ADP
fnp-3528	219	28	synthetic	synthetic	ADJ
fnp-3528	219	29	derivatives	derivative	NOUN
fnp-3528	219	30	,	,	PUNCT
fnp-3528	219	31	such	such	ADJ
fnp-3528	219	32	as	as	ADP
fnp-3528	219	33	8	8	NUM
fnp-3528	219	34	-	-	PUNCT
fnp-3528	219	35	bromo	bromo	NOUN
fnp-3528	219	36	-	-	PUNCT
fnp-3528	219	37	camp	camp	NOUN
fnp-3528	219	38	(	(	PUNCT
fnp-3528	219	39	8	8	NUM
fnp-3528	219	40	-	-	PUNCT
fnp-3528	219	41	br	br	NOUN
fnp-3528	219	42	-	-	PUNCT
fnp-3528	219	43	camp	camp	NOUN
fnp-3528	219	44	;	;	PUNCT
fnp-3528	219	45	figure	figure	NOUN
fnp-3528	219	46	 	 	SPACE
fnp-3528	219	47	2),230,249,255,266,290,292	2),230,249,255,266,290,292	NUM
fnp-3528	219	48	8-(4	8-(4	PROPN
fnp-3528	219	49	-	-	PUNCT
fnp-3528	219	50	chlorophenylthio)-camp	chlorophenylthio)-camp	PROPN
fnp-3528	219	51	(	(	PUNCT
fnp-3528	219	52	cpt	cpt	PROPN
fnp-3528	219	53	-	-	PUNCT
fnp-3528	219	54	camp),273,291,384	camp),273,291,384	ADJ
fnp-3528	219	55	and	and	CCONJ
fnp-3528	219	56	dibutyryl	dibutyryl	NOUN
fnp-3528	219	57	-	-	PUNCT
fnp-3528	219	58	camp.385	camp.385	NOUN
fnp-3528	219	59	-	-	PUNCT
fnp-3528	219	60	387	387	NUM
fnp-3528	219	61	the	the	DET
fnp-3528	219	62	observed	observed	ADJ
fnp-3528	219	63	effects	effect	NOUN
fnp-3528	219	64	ranged	range	VERB
fnp-3528	219	65	in	in	ADP
fnp-3528	219	66	the	the	DET
fnp-3528	219	67	same	same	ADJ
fnp-3528	219	68	order	order	NOUN
fnp-3528	219	69	of	of	ADP
fnp-3528	219	70	magnitude	magnitude	NOUN
fnp-3528	219	71	as	as	SCONJ
fnp-3528	219	72	the	the	DET
fnp-3528	219	73	combination	combination	NOUN
fnp-3528	219	74	of	of	ADP
fnp-3528	219	75	22-(r)-hydroxycholesterol	22-(r)-hydroxycholesterol	NUM
fnp-3528	219	76	and	and	CCONJ
fnp-3528	219	77	9	9	NUM
fnp-3528	219	78	-	-	PUNCT
fnp-3528	219	79	cis	cis	NOUN
fnp-3528	219	80	-	-	PUNCT
fnp-3528	219	81	retoic	retoic	ADJ
fnp-3528	219	82	acid.313	acid.313	PROPN
fnp-3528	219	83	the	the	DET
fnp-3528	219	84	increase	increase	NOUN
fnp-3528	219	85	in	in	ADP
fnp-3528	219	86	abca1	abca1	NOUN
fnp-3528	219	87	/	/	SYM
fnp-3528	219	88	abca1	abca1	NOUN
fnp-3528	219	89	mrna	mrna	NOUN
fnp-3528	219	90	and	and	CCONJ
fnp-3528	219	91	abca1	abca1	NOUN
fnp-3528	219	92	protein	protein	NOUN
fnp-3528	219	93	levels	level	NOUN
fnp-3528	219	94	was	be	AUX
fnp-3528	219	95	reflected	reflect	VERB
fnp-3528	219	96	in	in	ADP
fnp-3528	219	97	an	an	DET
fnp-3528	219	98	enhancement	enhancement	NOUN
fnp-3528	219	99	of	of	ADP
fnp-3528	219	100	abca1	abca1	NOUN
fnp-3528	219	101	-	-	PUNCT
fnp-3528	219	102	mediated	mediate	VERB
fnp-3528	219	103	cholesterol	cholesterol	NOUN
fnp-3528	219	104	and	and	CCONJ
fnp-3528	219	105	phospholipid	phospholipid	NOUN
fnp-3528	219	106	efflux,249,255,386	efflux,249,255,386	VERB
fnp-3528	219	107	and	and	CCONJ
fnp-3528	219	108	increased	increase	VERB
fnp-3528	219	109	apoa1	apoa1	NOUN
fnp-3528	220	1	binding	bind	VERB
fnp-3528	220	2	to	to	ADP
fnp-3528	220	3	murine	murine	ADJ
fnp-3528	220	4	raw264.7	raw264.7	ADJ
fnp-3528	220	5	macrophages.385	macrophages.385	PROPN
fnp-3528	220	6	-	-	PUNCT
fnp-3528	220	7	387	387	NUM
fnp-3528	220	8	similar	similar	ADJ
fnp-3528	220	9	observations	observation	NOUN
fnp-3528	220	10	have	have	AUX
fnp-3528	220	11	been	be	AUX
fnp-3528	220	12	made	make	VERB
fnp-3528	220	13	for	for	ADP
fnp-3528	220	14	the	the	DET
fnp-3528	220	15	pkc	pkc	PROPN
fnp-3528	220	16	stimulant	stimulant	ADJ
fnp-3528	220	17	phorbol	phorbol	NOUN
fnp-3528	220	18	12	12	NUM
fnp-3528	220	19	-	-	PUNCT
fnp-3528	220	20	myristate	myristate	ADJ
fnp-3528	220	21	13	13	NUM
fnp-3528	220	22	-	-	PUNCT
fnp-3528	220	23	acetate	acetate	NOUN
fnp-3528	220	24	(	(	PUNCT
fnp-3528	220	25	pma	pma	PROPN
fnp-3528	220	26	)	)	PUNCT
fnp-3528	220	27	,	,	PUNCT
fnp-3528	220	28	which	which	PRON
fnp-3528	220	29	induced	induce	VERB
fnp-3528	220	30	abca1	abca1	NOUN
fnp-3528	220	31	protein	protein	NOUN
fnp-3528	220	32	expression	expression	NOUN
fnp-3528	220	33	and	and	CCONJ
fnp-3528	220	34	abca1	abca1	NOUN
fnp-3528	220	35	-	-	PUNCT
fnp-3528	220	36	mediated	mediate	VERB
fnp-3528	220	37	cholesterol	cholesterol	NOUN
fnp-3528	220	38	and	and	CCONJ
fnp-3528	220	39	phospholipid	phospholipid	NOUN
fnp-3528	220	40	release.386	release.386	VERB
fnp-3528	220	41	pma	pma	NOUN
fnp-3528	220	42	is	be	AUX
fnp-3528	220	43	also	also	ADV
fnp-3528	220	44	the	the	DET
fnp-3528	220	45	standard	standard	ADJ
fnp-3528	220	46	substance	substance	NOUN
fnp-3528	220	47	used	use	VERB
fnp-3528	220	48	to	to	PART
fnp-3528	220	49	differentiate	differentiate	VERB
fnp-3528	220	50	human	human	ADJ
fnp-3528	220	51	monocytic	monocytic	ADJ
fnp-3528	220	52	leukemia	leukemia	NOUN
fnp-3528	220	53	cells	cell	NOUN
fnp-3528	220	54	into	into	ADP
fnp-3528	220	55	thp-1	thp-1	SYM
fnp-3528	220	56	macrophages	macrophage	NOUN
fnp-3528	220	57	–	–	PUNCT
fnp-3528	220	58	a	a	DET
fnp-3528	220	59	standard	standard	ADJ
fnp-3528	220	60	host	host	NOUN
fnp-3528	220	61	system	system	NOUN
fnp-3528	220	62	for	for	ADP
fnp-3528	220	63	abca	abca	NOUN
fnp-3528	220	64	transporter	transporter	NOUN
fnp-3528	220	65	evaluation.231,245,249,256,268,272,275,292,308,310,312	evaluation.231,245,249,256,268,272,275,292,308,310,312	NOUN
fnp-3528	220	66	-	-	SYM
fnp-3528	220	67	316,321,328,335,338	316,321,328,335,338	NUM
fnp-3528	220	68	,	,	PUNCT
fnp-3528	220	69	​339,341,342,360,363,364,366,377,384,388	​339,341,342,360,363,364,366,377,384,388	NOUN
fnp-3528	220	70	-	-	PUNCT
fnp-3528	220	71	397	397	NUM
fnp-3528	220	72	regarding	regard	VERB
fnp-3528	220	73	the	the	DET
fnp-3528	220	74	ampk	ampk	NOUN
fnp-3528	220	75	pathway	pathway	NOUN
fnp-3528	220	76	(	(	PUNCT
fnp-3528	220	77	figure	figure	NOUN
fnp-3528	220	78	 	 	SPACE
fnp-3528	220	79	3	3	NUM
fnp-3528	220	80	)	)	PUNCT
fnp-3528	220	81	,	,	PUNCT
fnp-3528	220	82	the	the	DET
fnp-3528	220	83	natural	natural	ADJ
fnp-3528	220	84	compound	compound	NOUN
fnp-3528	220	85	curcumin	curcumin	NOUN
fnp-3528	220	86	induced	induce	VERB
fnp-3528	220	87	abca1	abca1	NOUN
fnp-3528	220	88	/	/	SYM
fnp-3528	220	89	abca1	abca1	NOUN
fnp-3528	220	90	mrna338,388	mrna338,388	NUM
fnp-3528	220	91	and	and	CCONJ
fnp-3528	220	92	abca1	abca1	NOUN
fnp-3528	220	93	protein	protein	NOUN
fnp-3528	220	94	levels388,394	levels388,394	NOUN
fnp-3528	220	95	as	as	ADV
fnp-3528	220	96	well	well	ADV
fnp-3528	220	97	as	as	ADP
fnp-3528	220	98	cholesterol	cholesterol	NOUN
fnp-3528	220	99	efflux338,388,394	efflux338,388,394	X
fnp-3528	220	100	in	in	ADP
fnp-3528	220	101	thp-1338,388,394	thp-1338,388,394	NOUN
fnp-3528	220	102	and	and	CCONJ
fnp-3528	220	103	raw264.7394	raw264.7394	NOUN
fnp-3528	220	104	macrophages	macrophage	NOUN
fnp-3528	220	105	,	,	PUNCT
fnp-3528	220	106	which	which	PRON
fnp-3528	220	107	was	be	AUX
fnp-3528	220	108	also	also	ADV
fnp-3528	220	109	mediated	mediate	VERB
fnp-3528	220	110	through	through	ADP
fnp-3528	220	111	lxr	lxr	PROPN
fnp-3528	220	112	-	-	PUNCT
fnp-3528	220	113	α	α	NOUN
fnp-3528	220	114	activation.338	activation.338	NOUN
fnp-3528	220	115	however	however	ADV
fnp-3528	220	116	,	,	PUNCT
fnp-3528	220	117	these	these	DET
fnp-3528	220	118	lxr	lxr	NOUN
fnp-3528	220	119	-	-	PUNCT
fnp-3528	220	120	α	α	NOUN
fnp-3528	220	121	activating	activate	VERB
fnp-3528	220	122	effects	effect	NOUN
fnp-3528	220	123	were	be	AUX
fnp-3528	220	124	much	much	ADV
fnp-3528	220	125	more	more	ADV
fnp-3528	220	126	pronounced	pronounce	VERB
fnp-3528	220	127	in	in	ADP
fnp-3528	220	128	combination	combination	NOUN
fnp-3528	220	129	with	with	ADP
fnp-3528	220	130	the	the	DET
fnp-3528	220	131	gold	gold	ADJ
fnp-3528	220	132	standard	standard	NOUN
fnp-3528	220	133	to901317.338	to901317.338	PROPN
fnp-3528	220	134	other	other	ADJ
fnp-3528	220	135	ampk	ampk	NOUN
fnp-3528	220	136	-	-	PUNCT
fnp-3528	220	137	targeting	target	VERB
fnp-3528	220	138	agents	agent	NOUN
fnp-3528	220	139	are	be	AUX
fnp-3528	220	140	a	a	DET
fnp-3528	220	141	769662	769662	NUM
fnp-3528	220	142	and	and	CCONJ
fnp-3528	221	1	metformin,398	metformin,398	ADP
fnp-3528	221	2	which	which	PRON
fnp-3528	221	3	induced	induce	VERB
fnp-3528	221	4	abca1	abca1	NOUN
fnp-3528	221	5	/	/	SYM
fnp-3528	221	6	abca1,398	abca1,398	PROPN
fnp-3528	221	7	lxra	lxra	NOUN
fnp-3528	221	8	/	/	SYM
fnp-3528	221	9	lxra,396,398	lxra,396,398	NOUN
fnp-3528	221	10	and	and	CCONJ
fnp-3528	221	11	lxrb/	lxrb/	NUM
fnp-3528	221	12	lxrb396,398	lxrb396,398	NOUN
fnp-3528	221	13	in	in	ADP
fnp-3528	221	14	human398	human398	PROPN
fnp-3528	221	15	and	and	CCONJ
fnp-3528	221	16	murine	murine	ADJ
fnp-3528	221	17	(	(	PUNCT
fnp-3528	221	18	primary	primary	NOUN
fnp-3528	221	19	)	)	PUNCT
fnp-3528	221	20	macrophages,398	macrophages,398	PROPN
fnp-3528	221	21	leading	lead	VERB
fnp-3528	221	22	to	to	ADP
fnp-3528	221	23	increased	increase	VERB
fnp-3528	221	24	cholesterol	cholesterol	NOUN
fnp-3528	221	25	efflux.396	efflux.396	NOUN
fnp-3528	221	26	concerning	concern	VERB
fnp-3528	221	27	the	the	DET
fnp-3528	221	28	mapk	mapk	NOUN
fnp-3528	221	29	pathway	pathway	NOUN
fnp-3528	221	30	(	(	PUNCT
fnp-3528	221	31	figure	figure	NOUN
fnp-3528	221	32	 	 	SPACE
fnp-3528	221	33	3	3	NUM
fnp-3528	221	34	)	)	PUNCT
fnp-3528	221	35	,	,	PUNCT
fnp-3528	221	36	the	the	DET
fnp-3528	221	37	sterane	sterane	NOUN
fnp-3528	221	38	glycoside	glycoside	NOUN
fnp-3528	221	39	ginsenoside	ginsenoside	PROPN
fnp-3528	221	40	compound	compound	PROPN
fnp-3528	221	41	k	k	NOUN
fnp-3528	221	42	increased	increase	VERB
fnp-3528	221	43	abca1	abca1	NOUN
fnp-3528	221	44	mrna	mrna	PROPN
fnp-3528	221	45	and	and	CCONJ
fnp-3528	221	46	abca1	abca1	NOUN
fnp-3528	221	47	protein	protein	NOUN
fnp-3528	221	48	levels	level	NOUN
fnp-3528	221	49	in	in	ADP
fnp-3528	221	50	murine	murine	ADJ
fnp-3528	221	51	macrophages	macrophage	NOUN
fnp-3528	221	52	,	,	PUNCT
fnp-3528	221	53	reducing	reduce	VERB
fnp-3528	221	54	intracellular	intracellular	ADJ
fnp-3528	221	55	lipid	lipid	NOUN
fnp-3528	221	56	content	content	NOUN
fnp-3528	221	57	and	and	CCONJ
fnp-3528	221	58	promoting	promote	VERB
fnp-3528	221	59	autophagy.399	autophagy.399	NOUN
fnp-3528	221	60	these	these	DET
fnp-3528	221	61	effects	effect	NOUN
fnp-3528	221	62	were	be	AUX
fnp-3528	221	63	pinned	pin	VERB
fnp-3528	221	64	to	to	ADP
fnp-3528	221	65	a	a	DET
fnp-3528	221	66	negative	negative	ADJ
fnp-3528	221	67	impact	impact	NOUN
fnp-3528	221	68	on	on	ADP
fnp-3528	221	69	the	the	DET
fnp-3528	221	70	mapk	mapk	NOUN
fnp-3528	221	71	pathway	pathway	NOUN
fnp-3528	221	72	.	.	PUNCT
fnp-3528	222	1	finally	finally	ADV
fnp-3528	222	2	,	,	PUNCT
fnp-3528	222	3	a	a	DET
fnp-3528	222	4	synthetic	synthetic	ADJ
fnp-3528	222	5	inhibitor	inhibitor	NOUN
fnp-3528	222	6	of	of	ADP
fnp-3528	222	7	mapk	mapk	NOUN
fnp-3528	222	8	,	,	PUNCT
fnp-3528	222	9	sb203580	sb203580	PROPN
fnp-3528	222	10	,	,	PUNCT
fnp-3528	222	11	was	be	AUX
fnp-3528	222	12	shown	show	VERB
fnp-3528	222	13	to	to	PART
fnp-3528	222	14	induce	induce	VERB
fnp-3528	222	15	abca1	abca1	NOUN
fnp-3528	222	16	protein	protein	NOUN
fnp-3528	222	17	in	in	ADP
fnp-3528	222	18	combination	combination	NOUN
fnp-3528	222	19	with	with	ADP
fnp-3528	222	20	the	the	DET
fnp-3528	222	21	above	above	ADJ
fnp-3528	222	22	mentioned	mention	VERB
fnp-3528	222	23	geniposide	geniposide	ADV
fnp-3528	222	24	in	in	ADP
fnp-3528	222	25	vitro	vitro	X
fnp-3528	222	26	in	in	ADP
fnp-3528	222	27	murine	murine	ADJ
fnp-3528	222	28	macrophages.375	macrophages.375	PROPN
fnp-3528	222	29	abca1	abca1	NOUN
fnp-3528	222	30	the	the	DET
fnp-3528	222	31	ppar	ppar	NOUN
fnp-3528	222	32	pathway	pathway	NOUN
fnp-3528	222	33	another	another	DET
fnp-3528	222	34	well	well	ADV
fnp-3528	222	35	-	-	PUNCT
fnp-3528	222	36	known	know	VERB
fnp-3528	222	37	approach	approach	NOUN
fnp-3528	222	38	to	to	PART
fnp-3528	222	39	induce	induce	VERB
fnp-3528	222	40	abca1	abca1	NOUN
fnp-3528	222	41	involves	involve	VERB
fnp-3528	222	42	the	the	DET
fnp-3528	222	43	ppar	ppar	NOUN
fnp-3528	222	44	pathway	pathway	NOUN
fnp-3528	222	45	(	(	PUNCT
fnp-3528	222	46	figure	figure	NOUN
fnp-3528	222	47	 	 	SPACE
fnp-3528	222	48	3).268,272,295,309,315,321,326	3).268,272,295,309,315,321,326	NOUN
fnp-3528	222	49	,	,	PUNCT
fnp-3528	222	50	327,337,343,395,400	327,337,343,395,400	NUM
fnp-3528	222	51	-	-	PUNCT
fnp-3528	222	52	409	409	NUM
fnp-3528	222	53	certain	certain	ADJ
fnp-3528	222	54	ppar	ppar	NOUN
fnp-3528	222	55	/	/	SYM
fnp-3528	222	56	ppar	ppar	NOUN
fnp-3528	222	57	inducers	inducer	NOUN
fnp-3528	222	58	and/or	and/or	CCONJ
fnp-3528	222	59	ppar	ppar	NOUN
fnp-3528	222	60	activators	activator	NOUN
fnp-3528	222	61	have	have	AUX
fnp-3528	222	62	been	be	AUX
fnp-3528	222	63	described	describe	VERB
fnp-3528	222	64	above	above	ADV
fnp-3528	222	65	,	,	PUNCT
fnp-3528	222	66	as	as	SCONJ
fnp-3528	222	67	these	these	DET
fnp-3528	222	68	modulators	modulator	NOUN
fnp-3528	222	69	also	also	ADV
fnp-3528	222	70	have	have	VERB
fnp-3528	222	71	effects	effect	NOUN
fnp-3528	222	72	on	on	ADP
fnp-3528	222	73	the	the	DET
fnp-3528	222	74	lxr	lxr	NOUN
fnp-3528	222	75	pathway.321,361,372,373,377	pathway.321,361,372,373,377	ADP
fnp-3528	222	76	several	several	ADJ
fnp-3528	222	77	natural	natural	ADJ
fnp-3528	222	78	compounds	compound	NOUN
fnp-3528	222	79	target	target	VERB
fnp-3528	222	80	the	the	DET
fnp-3528	222	81	ppar	ppar	NOUN
fnp-3528	222	82	pathway	pathway	NOUN
fnp-3528	222	83	,	,	PUNCT
fnp-3528	222	84	such	such	ADJ
fnp-3528	222	85	as	as	ADP
fnp-3528	222	86	the	the	DET
fnp-3528	222	87	flavonoids	flavonoid	NOUN
fnp-3528	222	88	homo	homo	NOUN
fnp-3528	222	89	-	-	PUNCT
fnp-3528	222	90	eriodictyol,402	eriodictyol,402	NOUN
fnp-3528	222	91	hesperetin-7	hesperetin-7	PROPN
fnp-3528	222	92	-	-	PUNCT
fnp-3528	222	93	o	o	NOUN
fnp-3528	222	94	-	-	PUNCT
fnp-3528	222	95	β	β	NOUN
fnp-3528	222	96	-	-	ADJ
fnp-3528	222	97	d	d	NOUN
fnp-3528	222	98	-	-	PUNCT
fnp-3528	222	99	glucopyrano	glucopyrano	NOUN
fnp-3528	222	100	-	-	PUNCT
fnp-3528	222	101	side,402	side,402	PROPN
fnp-3528	222	102	scutellarein,403	scutellarein,403	PROPN
fnp-3528	222	103	and	and	CCONJ
fnp-3528	222	104	the	the	DET
fnp-3528	222	105	antimycotic	antimycotic	ADJ
fnp-3528	222	106	trichostatin	trichostatin	NOUN
fnp-3528	222	107	a.410	a.410	ADP
fnp-3528	222	108	these	these	DET
fnp-3528	222	109	compounds	compound	NOUN
fnp-3528	222	110	increased	increase	VERB
fnp-3528	222	111	abca1402	abca1402	PROPN
fnp-3528	222	112	and	and	CCONJ
fnp-3528	222	113	pparg402	pparg402	PROPN
fnp-3528	222	114	mrna	mrna	PROPN
fnp-3528	222	115	as	as	ADV
fnp-3528	222	116	well	well	ADV
fnp-3528	222	117	as	as	ADP
fnp-3528	222	118	abca1,402,410	abca1,402,410	VERB
fnp-3528	222	119	ppar	ppar	NOUN
fnp-3528	222	120	-	-	PUNCT
fnp-3528	222	121	α,403	α,403	NOUN
fnp-3528	222	122	and	and	CCONJ
fnp-3528	222	123	ppar	ppar	NOUN
fnp-3528	222	124	-	-	PUNCT
fnp-3528	222	125	γ402,410	γ402,410	NOUN
fnp-3528	222	126	protein	protein	NOUN
fnp-3528	222	127	levels	level	NOUN
fnp-3528	222	128	in	in	ADP
fnp-3528	222	129	vitro402,410	vitro402,410	PROPN
fnp-3528	222	130	and	and	CCONJ
fnp-3528	222	131	in	in	ADP
fnp-3528	222	132	vivo.403	vivo.403	NOUN
fnp-3528	222	133	decreased	decrease	VERB
fnp-3528	222	134	intracellular	intracellular	ADJ
fnp-3528	222	135	cholesterol	cholesterol	NOUN
fnp-3528	222	136	levels	level	NOUN
fnp-3528	222	137	were	be	AUX
fnp-3528	222	138	also	also	ADV
fnp-3528	222	139	observed.402	observed.402	NUM
fnp-3528	222	140	trichostatin	trichostatin	NOUN
fnp-3528	222	141	a	a	DET
fnp-3528	222	142	reduced	reduce	VERB
fnp-3528	222	143	aortic	aortic	ADJ
fnp-3528	222	144	atherosclerotic	atherosclerotic	ADJ
fnp-3528	222	145	plaques	plaque	NOUN
fnp-3528	222	146	in	in	ADP
fnp-3528	222	147	high	high	ADJ
fnp-3528	222	148	-	-	PUNCT
fnp-3528	222	149	fat	fat	NOUN
fnp-3528	222	150	diet	diet	NOUN
fnp-3528	222	151	-	-	PUNCT
fnp-3528	222	152	fed	feed	VERB
fnp-3528	222	153	apoe	apoe	ADJ
fnp-3528	222	154	knock	knock	NOUN
fnp-3528	222	155	-	-	PUNCT
fnp-3528	222	156	out	out	NOUN
fnp-3528	222	157	mice,410	mice,410	PROPN
fnp-3528	222	158	and	and	CCONJ
fnp-3528	222	159	an	an	DET
fnp-3528	222	160	upregulation	upregulation	NOUN
fnp-3528	222	161	of	of	ADP
fnp-3528	222	162	abca1	abca1	NOUN
fnp-3528	222	163	,	,	PUNCT
fnp-3528	222	164	ppar	ppar	NOUN
fnp-3528	222	165	-	-	PUNCT
fnp-3528	222	166	γ	γ	X
fnp-3528	222	167	,	,	PUNCT
fnp-3528	222	168	and	and	CCONJ
fnp-3528	222	169	lxr	lxr	PROPN
fnp-3528	222	170	-	-	PUNCT
fnp-3528	222	171	α	α	NOUN
fnp-3528	222	172	/	/	SYM
fnp-3528	222	173	β	β	NOUN
fnp-3528	222	174	protein	protein	NOUN
fnp-3528	222	175	levels	level	NOUN
fnp-3528	222	176	was	be	AUX
fnp-3528	222	177	observed	observe	VERB
fnp-3528	222	178	in	in	ADP
fnp-3528	222	179	aortic	aortic	ADJ
fnp-3528	222	180	cells	cell	NOUN
fnp-3528	222	181	as	as	ADV
fnp-3528	222	182	well	well	ADV
fnp-3528	222	183	as	as	ADV
fnp-3528	222	184	peritoneal	peritoneal	ADJ
fnp-3528	222	185	macrophages.410	macrophages.410	ADP
fnp-3528	222	186	several	several	ADJ
fnp-3528	222	187	drugs	drug	NOUN
fnp-3528	222	188	and	and	CCONJ
fnp-3528	222	189	drug	drug	NOUN
fnp-3528	222	190	-	-	PUNCT
fnp-3528	222	191	like	like	ADJ
fnp-3528	222	192	ppar	ppar	NOUN
fnp-3528	222	193	agonists	agonist	NOUN
fnp-3528	222	194	were	be	AUX
fnp-3528	222	195	revealed	reveal	VERB
fnp-3528	222	196	to	to	PART
fnp-3528	222	197	induce	induce	VERB
fnp-3528	222	198	abca1	abca1	NOUN
fnp-3528	222	199	/	/	SYM
fnp-3528	222	200	abca1	abca1	NOUN
fnp-3528	222	201	mrna	mrna	PROPN
fnp-3528	222	202	and/or	and/or	CCONJ
fnp-3528	222	203	abca1	abca1	NOUN
fnp-3528	222	204	protein	protein	NOUN
fnp-3528	222	205	content	content	NOUN
fnp-3528	222	206	,	,	PUNCT
fnp-3528	222	207	including	include	VERB
fnp-3528	222	208	the	the	DET
fnp-3528	222	209	ppar	ppar	NOUN
fnp-3528	222	210	-	-	PUNCT
fnp-3528	222	211	α	α	NOUN
fnp-3528	222	212	agonists	agonist	NOUN
fnp-3528	222	213	fenofibrate,326,400,404	fenofibrate,326,400,404	NOUN
fnp-3528	222	214	pemafibrate	pemafibrate	NOUN
fnp-3528	222	215	(	(	PUNCT
fnp-3528	222	216	k	k	X
fnp-3528	222	217	877),405	877),405	NOUN
fnp-3528	222	218	wy14643,268,343	wy14643,268,343	NOUN
fnp-3528	222	219	and	and	CCONJ
fnp-3528	222	220	rpr-5,268	rpr-5,268	ADP
fnp-3528	222	221	as	as	ADV
fnp-3528	222	222	well	well	ADV
fnp-3528	222	223	as	as	ADP
fnp-3528	222	224	the	the	DET
fnp-3528	222	225	ppar	ppar	NOUN
fnp-3528	222	226	-	-	PUNCT
fnp-3528	222	227	γ	γ	NOUN
fnp-3528	222	228	agonists	agonist	NOUN
fnp-3528	222	229	efatutazone,337	efatutazone,337	INTJ
fnp-3528	223	1	pioglitazone,272,309,326,395,407	pioglitazone,272,309,326,395,407	INTJ
fnp-3528	223	2	pitavastatin,343	pitavastatin,343	VERB
fnp-3528	223	3	prostaglandin	prostaglandin	NOUN
fnp-3528	223	4	j2	j2	NOUN
fnp-3528	223	5	(	(	PUNCT
fnp-3528	223	6	pg	pg	NOUN
fnp-3528	223	7	-	-	PUNCT
fnp-3528	223	8	j2),268,327	j2),268,327	ADJ
fnp-3528	223	9	rosiglitazone	rosiglitazone	NOUN
fnp-3528	223	10	(	(	PUNCT
fnp-3528	223	11	figure	figure	NOUN
fnp-3528	223	12	 	 	SPACE
fnp-3528	223	13	2),268,309,315,408,409	2),268,309,315,408,409	NUM
fnp-3528	223	14	troglitazone,268	troglitazone,268	PROPN
fnp-3528	223	15	and	and	CCONJ
fnp-3528	223	16	gw7845,315	gw7845,315	PROPN
fnp-3528	223	17	but	but	CCONJ
fnp-3528	223	18	also	also	ADV
fnp-3528	223	19	the	the	DET
fnp-3528	223	20	broad	broad	ADJ
fnp-3528	223	21	-	-	PUNCT
fnp-3528	223	22	spectrum	spectrum	NOUN
fnp-3528	223	23	ppar	ppar	NOUN
fnp-3528	223	24	-	-	PUNCT
fnp-3528	223	25	α	α	NOUN
fnp-3528	223	26	,	,	PUNCT
fnp-3528	223	27	ppar	ppar	NOUN
fnp-3528	223	28	-	-	PUNCT
fnp-3528	223	29	β	β	NOUN
fnp-3528	223	30	,	,	PUNCT
fnp-3528	223	31	and	and	CCONJ
fnp-3528	223	32	ppar	ppar	NOUN
fnp-3528	223	33	-	-	PUNCT
fnp-3528	223	34	γ	γ	X
fnp-3528	223	35	agonist	agonist	NOUN
fnp-3528	223	36	bezafibrate268,327	bezafibrate268,327	NOUN
fnp-3528	223	37	and	and	CCONJ
fnp-3528	223	38	the	the	DET
fnp-3528	223	39	multitarget	multitarget	PROPN
fnp-3528	223	40	ppar	ppar	NOUN
fnp-3528	223	41	-	-	PUNCT
fnp-3528	223	42	α	α	NOUN
fnp-3528	223	43	,	,	PUNCT
fnp-3528	223	44	ppar	ppar	NOUN
fnp-3528	223	45	-	-	PUNCT
fnp-3528	223	46	γ	γ	NOUN
fnp-3528	223	47	,	,	PUNCT
fnp-3528	223	48	and	and	CCONJ
fnp-3528	223	49	ppar	ppar	NOUN
fnp-3528	223	50	-	-	PUNCT
fnp-3528	223	51	δ	δ	NOUN
fnp-3528	223	52	agonist	agonist	NOUN
fnp-3528	223	53	tetradecylthioacetic	tetradecylthioacetic	ADJ
fnp-3528	223	54	acid.401	acid.401	NOUN
fnp-3528	223	55	this	this	DET
fnp-3528	223	56	induction	induction	NOUN
fnp-3528	223	57	was	be	AUX
fnp-3528	223	58	observed	observe	VERB
fnp-3528	223	59	for	for	ADP
fnp-3528	223	60	abca1	abca1	NOUN
fnp-3528	223	61	/	/	SYM
fnp-3528	223	62	abca1	abca1	NOUN
fnp-3528	223	63	mrna268,315,343,401,405	mrna268,315,343,401,405	PROPN
fnp-3528	223	64	as	as	ADV
fnp-3528	223	65	well	well	ADV
fnp-3528	223	66	as	as	ADP
fnp-3528	223	67	abca1	abca1	NOUN
fnp-3528	223	68	protein	protein	NOUN
fnp-3528	223	69	levels,268,337,343,395,405,409	levels,268,337,343,395,405,409	ADV
fnp-3528	223	70	and	and	CCONJ
fnp-3528	223	71	was	be	AUX
fnp-3528	223	72	functionally	functionally	ADV
fnp-3528	223	73	confirmed	confirm	VERB
fnp-3528	223	74	by	by	ADP
fnp-3528	223	75	increased	increase	VERB
fnp-3528	223	76	cholesterol	cholesterol	NOUN
fnp-3528	223	77	efflux.268,315	efflux.268,315	PROPN
fnp-3528	223	78	a	a	DET
fnp-3528	223	79	connection	connection	NOUN
fnp-3528	223	80	between	between	ADP
fnp-3528	223	81	the	the	DET
fnp-3528	223	82	ppar	ppar	NOUN
fnp-3528	223	83	and	and	CCONJ
fnp-3528	223	84	lxr	lxr	PROPN
fnp-3528	223	85	pathways	pathway	NOUN
fnp-3528	223	86	has	have	AUX
fnp-3528	223	87	also	also	ADV
fnp-3528	223	88	been	be	AUX
fnp-3528	223	89	drawn,268,326,327,337,400	drawn,268,326,327,337,400	NOUN
fnp-3528	223	90	highlighting	highlight	VERB
fnp-3528	223	91	the	the	DET
fnp-3528	223	92	importance	importance	NOUN
fnp-3528	223	93	of	of	ADP
fnp-3528	223	94	both	both	DET
fnp-3528	223	95	pathways	pathway	NOUN
fnp-3528	223	96	for	for	ADP
fnp-3528	223	97	abca1	abca1	NOUN
fnp-3528	223	98	/	/	SYM
fnp-3528	223	99	abca1	abca1	NOUN
fnp-3528	223	100	induction	induction	NOUN
fnp-3528	223	101	.	.	PUNCT
fnp-3528	224	1	furthermore	furthermore	ADV
fnp-3528	224	2	,	,	PUNCT
fnp-3528	224	3	fenofibrate	fenofibrate	PROPN
fnp-3528	224	4	had	have	VERB
fnp-3528	224	5	a	a	DET
fnp-3528	224	6	positive	positive	ADJ
fnp-3528	224	7	impact	impact	NOUN
fnp-3528	224	8	on	on	ADP
fnp-3528	224	9	both	both	CCONJ
fnp-3528	224	10	the	the	DET
fnp-3528	224	11	lxr	lxr	PROPN
fnp-3528	224	12	-	-	PUNCT
fnp-3528	224	13	α	α	PROPN
fnp-3528	224	14	and	and	CCONJ
fnp-3528	224	15	ampk	ampk	PROPN
fnp-3528	224	16	pathways400	pathways400	PROPN
fnp-3528	224	17	certain	certain	ADJ
fnp-3528	224	18	ppar	ppar	NOUN
fnp-3528	224	19	agonists	agonist	NOUN
fnp-3528	224	20	have	have	AUX
fnp-3528	224	21	been	be	AUX
fnp-3528	224	22	used	use	VERB
fnp-3528	224	23	as	as	ADP
fnp-3528	224	24	standard	standard	ADJ
fnp-3528	224	25	inducers	inducer	NOUN
fnp-3528	224	26	of	of	ADP
fnp-3528	224	27	abca1	abca1	NOUN
fnp-3528	224	28	,	,	PUNCT
fnp-3528	224	29	e.g.	e.g.	ADV
fnp-3528	224	30	,	,	PUNCT
fnp-3528	225	1	pioglitazone407	pioglitazone407	PROPN
fnp-3528	225	2	and	and	CCONJ
fnp-3528	225	3	rosiglitazone.408	rosiglitazone.408	VERB
fnp-3528	225	4	synthetic	synthetic	ADJ
fnp-3528	225	5	ppar	ppar	NOUN
fnp-3528	225	6	agonists	agonist	NOUN
fnp-3528	225	7	were	be	AUX
fnp-3528	225	8	also	also	ADV
fnp-3528	225	9	reported	report	VERB
fnp-3528	225	10	to	to	PART
fnp-3528	225	11	induce	induce	VERB
fnp-3528	225	12	abca1.406	abca1.406	ADV
fnp-3528	225	13	the	the	DET
fnp-3528	225	14	benzothiazole	benzothiazole	NOUN
fnp-3528	225	15	derivative	derivative	ADJ
fnp-3528	225	16	e3317	e3317	PROPN
fnp-3528	225	17	dose	dose	NOUN
fnp-3528	225	18	-	-	PUNCT
fnp-3528	225	19	dependently	dependently	ADV
fnp-3528	225	20	increased	increase	VERB
fnp-3528	225	21	abca1	abca1	NOUN
fnp-3528	225	22	/	/	SYM
fnp-3528	225	23	abca1	abca1	NOUN
fnp-3528	225	24	mrna	mrna	NOUN
fnp-3528	225	25	and	and	CCONJ
fnp-3528	225	26	abca1	abca1	NOUN
fnp-3528	225	27	protein	protein	NOUN
fnp-3528	225	28	levels	level	NOUN
fnp-3528	225	29	though	though	SCONJ
fnp-3528	225	30	ppar	ppar	NOUN
fnp-3528	225	31	-	-	PUNCT
fnp-3528	225	32	γ	γ	NOUN
fnp-3528	225	33	activation	activation	NOUN
fnp-3528	225	34	in	in	ADP
fnp-3528	225	35	several	several	ADJ
fnp-3528	225	36	cell	cell	NOUN
fnp-3528	225	37	lines.406	lines.406	NOUN
fnp-3528	225	38	this	this	PRON
fnp-3528	225	39	was	be	AUX
fnp-3528	225	40	reflected	reflect	VERB
fnp-3528	225	41	in	in	ADP
fnp-3528	225	42	decreased	decrease	VERB
fnp-3528	225	43	cholesterol	cholesterol	NOUN
fnp-3528	225	44	efflux	efflux	NOUN
fnp-3528	225	45	and	and	CCONJ
fnp-3528	225	46	reduced	reduce	VERB
fnp-3528	225	47	intracellular	intracellular	ADJ
fnp-3528	225	48	cholesterol	cholesterol	NOUN
fnp-3528	225	49	content	content	NOUN
fnp-3528	225	50	.	.	PUNCT
fnp-3528	226	1	finally	finally	ADV
fnp-3528	226	2	,	,	PUNCT
fnp-3528	226	3	a	a	DET
fnp-3528	226	4	molecular	molecular	ADJ
fnp-3528	226	5	docking	docking	NOUN
fnp-3528	226	6	approach	approach	NOUN
fnp-3528	226	7	to	to	PART
fnp-3528	226	8	discover	discover	VERB
fnp-3528	226	9	novel	novel	ADJ
fnp-3528	226	10	ppar	ppar	NOUN
fnp-3528	226	11	agonists	agonist	NOUN
fnp-3528	226	12	has	have	AUX
fnp-3528	226	13	yielded	yield	VERB
fnp-3528	226	14	gq-11	gq-11	X
fnp-3528	226	15	,	,	PUNCT
fnp-3528	226	16	which	which	PRON
fnp-3528	226	17	induced	induce	VERB
fnp-3528	226	18	abca1	abca1	PROPN
fnp-3528	226	19	mrna	mrna	NOUN
fnp-3528	226	20	in	in	ADP
fnp-3528	226	21	livers	liver	NOUN
fnp-3528	226	22	of	of	ADP
fnp-3528	226	23	c57bl/6	c57bl/6	NOUN
fnp-3528	226	24	ldlr	ldlr	ADJ
fnp-3528	226	25	knock	knock	VERB
fnp-3528	226	26	-	-	PUNCT
fnp-3528	226	27	out	out	ADP
fnp-3528	226	28	mice.407	mice.407	NOUN
fnp-3528	226	29	abca1	abca1	NOUN
fnp-3528	226	30	the	the	DET
fnp-3528	226	31	3	3	NUM
fnp-3528	226	32	-	-	PUNCT
fnp-3528	226	33	hydroxyl-3	hydroxyl-3	NUM
fnp-3528	226	34	-	-	PUNCT
fnp-3528	226	35	methyl	methyl	NOUN
fnp-3528	226	36	glutaryl-(hmg)-coa	glutaryl-(hmg)-coa	NOUN
fnp-3528	226	37	-	-	PUNCT
fnp-3528	226	38	reductase	reductase	NOUN
fnp-3528	226	39	pathway	pathway	NOUN
fnp-3528	226	40	other	other	ADJ
fnp-3528	226	41	targets	target	NOUN
fnp-3528	226	42	for	for	ADP
fnp-3528	226	43	abca1	abca1	NOUN
fnp-3528	226	44	/	/	SYM
fnp-3528	226	45	abca1	abca1	NOUN
fnp-3528	226	46	induction	induction	NOUN
fnp-3528	226	47	are	be	AUX
fnp-3528	226	48	the	the	DET
fnp-3528	226	49	3	3	NUM
fnp-3528	226	50	-	-	PUNCT
fnp-3528	226	51	hydroxyl-3	hydroxyl-3	NUM
fnp-3528	226	52	-	-	PUNCT
fnp-3528	226	53	methylglutaryl-(hmg)-coa	methylglutaryl-(hmg)-coa	ADJ
fnp-3528	226	54	-	-	PUNCT
fnp-3528	226	55	reduc	reduc	NOUN
fnp-3528	226	56	-	-	PUNCT
fnp-3528	226	57	tase	tase	NOUN
fnp-3528	226	58	and	and	CCONJ
fnp-3528	226	59	cellular	cellular	ADJ
fnp-3528	226	60	cholesterol	cholesterol	NOUN
fnp-3528	226	61	synthesis	synthesis	NOUN
fnp-3528	226	62	(	(	PUNCT
fnp-3528	226	63	figure	figure	NOUN
fnp-3528	226	64	 	 	SPACE
fnp-3528	226	65	3).318,343	3).318,343	NOUN
fnp-3528	226	66	several	several	ADJ
fnp-3528	226	67	hmg	hmg	NOUN
fnp-3528	226	68	-	-	PUNCT
fnp-3528	226	69	coa	coa	NOUN
fnp-3528	226	70	-	-	PUNCT
fnp-3528	226	71	reductase	reductase	NOUN
fnp-3528	226	72	inhibitors	inhibitor	NOUN
fnp-3528	226	73	such	such	ADJ
fnp-3528	226	74	as	as	ADP
fnp-3528	226	75	atorvastatin	atorvastatin	NOUN
fnp-3528	226	76	(	(	PUNCT
fnp-3528	226	77	figure	figure	NOUN
fnp-3528	226	78	 	 	SPACE
fnp-3528	226	79	2),330,343,362	2),330,343,362	NUM
fnp-3528	226	80	fluvastatin,312,411	fluvastatin,312,411	NOUN
fnp-3528	226	81	mevastatin	mevastatin	NOUN
fnp-3528	226	82	(	(	PUNCT
fnp-3528	226	83	compactin),318	compactin),318	NOUN
fnp-3528	226	84	pitavastatin,318,343	pitavastatin,318,343	NOUN
fnp-3528	226	85	and	and	CCONJ
fnp-3528	226	86	simvastatin312,343	simvastatin312,343	VERB
fnp-3528	226	87	increased	increase	VERB
fnp-3528	226	88	abca1	abca1	NOUN
fnp-3528	226	89	/	/	SYM
fnp-3528	226	90	abca1	abca1	NOUN
fnp-3528	226	91	mrna312,343	mrna312,343	NOUN
fnp-3528	226	92	and	and	CCONJ
fnp-3528	226	93	abca1	abca1	NOUN
fnp-3528	226	94	protein	protein	NOUN
fnp-3528	226	95	levels,362,411	levels,362,411	VERB
fnp-3528	226	96	as	as	ADV
fnp-3528	226	97	well	well	ADV
fnp-3528	226	98	as	as	ADP
fnp-3528	226	99	abca1	abca1	NOUN
fnp-3528	226	100	-	-	PUNCT
fnp-3528	226	101	mediated	mediate	VERB
fnp-3528	226	102	cholesterol	cholesterol	NOUN
fnp-3528	226	103	efflux.318	efflux.318	NOUN
fnp-3528	226	104	these	these	DET
fnp-3528	226	105	data	datum	NOUN
fnp-3528	226	106	are	be	AUX
fnp-3528	226	107	surprising	surprising	ADJ
fnp-3528	226	108	,	,	PUNCT
fnp-3528	226	109	as	as	SCONJ
fnp-3528	226	110	one	one	PRON
fnp-3528	226	111	might	might	AUX
fnp-3528	226	112	expect	expect	VERB
fnp-3528	226	113	the	the	DET
fnp-3528	226	114	loss	loss	NOUN
fnp-3528	226	115	-	-	PUNCT
fnp-3528	226	116	of	of	ADP
fnp-3528	226	117	-	-	PUNCT
fnp-3528	226	118	function	function	NOUN
fnp-3528	226	119	of	of	ADP
fnp-3528	226	120	an	an	DET
fnp-3528	226	121	enzyme	enzyme	NOUN
fnp-3528	226	122	in	in	ADP
fnp-3528	226	123	the	the	DET
fnp-3528	226	124	cholesterol	cholesterol	NOUN
fnp-3528	226	125	synthesis	synthesis	NOUN
fnp-3528	226	126	pathway	pathway	NOUN
fnp-3528	226	127	to	to	PART
fnp-3528	226	128	induce	induce	VERB
fnp-3528	226	129	a	a	DET
fnp-3528	226	130	decrease	decrease	NOUN
fnp-3528	226	131	of	of	ADP
fnp-3528	226	132	abca1	abca1	NOUN
fnp-3528	226	133	,	,	PUNCT
fnp-3528	226	134	preventing	prevent	VERB
fnp-3528	226	135	cholesterol	cholesterol	NOUN
fnp-3528	226	136	depletion	depletion	NOUN
fnp-3528	226	137	from	from	ADP
fnp-3528	226	138	cells.314384,412	cells.314384,412	X
fnp-3528	226	139	conversely	conversely	ADV
fnp-3528	226	140	,	,	PUNCT
fnp-3528	226	141	the	the	DET
fnp-3528	226	142	overproduction	overproduction	NOUN
fnp-3528	226	143	of	of	ADP
fnp-3528	226	144	cholesterol	cholesterol	NOUN
fnp-3528	226	145	leads	lead	VERB
fnp-3528	226	146	to	to	ADP
fnp-3528	226	147	the	the	DET
fnp-3528	226	148	opposite	opposite	ADJ
fnp-3528	226	149	effect	effect	NOUN
fnp-3528	226	150	,	,	PUNCT
fnp-3528	226	151	as	as	SCONJ
fnp-3528	226	152	demonstrated	demonstrate	VERB
fnp-3528	226	153	for	for	ADP
fnp-3528	226	154	mevalonate	mevalonate	NOUN
fnp-3528	226	155	,	,	PUNCT
fnp-3528	226	156	which	which	PRON
fnp-3528	226	157	is	be	AUX
fnp-3528	226	158	a	a	DET
fnp-3528	226	159	building	building	NOUN
fnp-3528	226	160	block	block	NOUN
fnp-3528	226	161	of	of	ADP
fnp-3528	226	162	cholesterol	cholesterol	NOUN
fnp-3528	226	163	synthesis413	synthesis413	PROPN
fnp-3528	226	164	and	and	CCONJ
fnp-3528	226	165	has	have	AUX
fnp-3528	226	166	been	be	AUX
fnp-3528	226	167	demonstrated	demonstrate	VERB
fnp-3528	226	168	to	to	PART
fnp-3528	226	169	increase	increase	VERB
fnp-3528	226	170	abca1	abca1	NOUN
fnp-3528	226	171	/	/	SYM
fnp-3528	226	172	abca1	abca1	NOUN
fnp-3528	226	173	mrna312,314	mrna312,314	NOUN
fnp-3528	226	174	and	and	CCONJ
fnp-3528	226	175	to	to	PART
fnp-3528	226	176	abrogate	abrogate	VERB
fnp-3528	226	177	abca1	abca1	NOUN
fnp-3528	227	1	downregulation.312	downregulation.312	PRON
fnp-3528	227	2	pitavastatin	pitavastatin	NOUN
fnp-3528	227	3	addressed	address	VERB
fnp-3528	227	4	srebp	srebp	ADJ
fnp-3528	227	5	-	-	PUNCT
fnp-3528	227	6	driven	drive	VERB
fnp-3528	227	7	promotor	promotor	NOUN
fnp-3528	227	8	regions	region	NOUN
fnp-3528	227	9	upregulating	upregulating	ADJ
fnp-3528	227	10	abca1	abca1	PROPN
fnp-3528	227	11	mrna	mrna	PROPN
fnp-3528	227	12	levels,343	levels,343	PROPN
fnp-3528	227	13	and	and	CCONJ
fnp-3528	227	14	atorvastatin	atorvastatin	PROPN
fnp-3528	227	15	reduced	reduce	VERB
fnp-3528	227	16	atherosclerotic	atherosclerotic	ADJ
fnp-3528	227	17	plaques	plaque	NOUN
fnp-3528	227	18	in	in	ADP
fnp-3528	227	19	apoe	apoe	ADJ
fnp-3528	227	20	knocked	knock	VERB
fnp-3528	227	21	-	-	PUNCT
fnp-3528	227	22	out	out	ADP
fnp-3528	227	23	c57bl/6	c57bl/6	NOUN
fnp-3528	227	24	mice	mouse	NOUN
fnp-3528	227	25	by	by	ADP
fnp-3528	227	26	induction	induction	NOUN
fnp-3528	227	27	of	of	ADP
fnp-3528	227	28	abca1	abca1	NOUN
fnp-3528	227	29	protein	protein	NOUN
fnp-3528	227	30	content	content	NOUN
fnp-3528	227	31	in	in	ADP
fnp-3528	227	32	the	the	DET
fnp-3528	227	33	murine	murine	ADJ
fnp-3528	227	34	aorta.362	aorta.362	VERB
fnp-3528	227	35	other	other	ADJ
fnp-3528	227	36	abca1	abca1	NOUN
fnp-3528	227	37	inducers	inducer	NOUN
fnp-3528	227	38	sterane	sterane	NOUN
fnp-3528	227	39	and	and	CCONJ
fnp-3528	227	40	sterane	sterane	NOUN
fnp-3528	227	41	-	-	PUNCT
fnp-3528	227	42	like	like	ADJ
fnp-3528	227	43	natural	natural	ADJ
fnp-3528	227	44	compounds	compound	NOUN
fnp-3528	227	45	several	several	ADJ
fnp-3528	227	46	other	other	ADJ
fnp-3528	227	47	agents	agent	NOUN
fnp-3528	227	48	were	be	AUX
fnp-3528	227	49	reported	report	VERB
fnp-3528	227	50	to	to	PART
fnp-3528	227	51	induce	induce	VERB
fnp-3528	227	52	abca1	abca1	NOUN
fnp-3528	227	53	/	/	SYM
fnp-3528	227	54	abca1	abca1	NOUN
fnp-3528	227	55	mrna	mrna	PROPN
fnp-3528	227	56	and/or	and/or	CCONJ
fnp-3528	227	57	abca1	abca1	NOUN
fnp-3528	227	58	protein	protein	NOUN
fnp-3528	227	59	level(s	level(s	PROPN
fnp-3528	227	60	)	)	PUNCT
fnp-3528	227	61	,	,	PUNCT
fnp-3528	227	62	with	with	ADP
fnp-3528	227	63	some	some	DET
fnp-3528	227	64	studies	study	NOUN
fnp-3528	227	65	reporting	report	VERB
fnp-3528	227	66	a	a	DET
fnp-3528	227	67	unique	unique	ADJ
fnp-3528	227	68	mechanism	mechanism	NOUN
fnp-3528	227	69	of	of	ADP
fnp-3528	227	70	action	action	NOUN
fnp-3528	227	71	for	for	ADP
fnp-3528	227	72	these	these	DET
fnp-3528	227	73	agents	agent	NOUN
fnp-3528	227	74	.	.	PUNCT
fnp-3528	228	1	such	such	ADJ
fnp-3528	228	2	compounds	compound	NOUN
fnp-3528	228	3	include	include	VERB
fnp-3528	228	4	the	the	DET
fnp-3528	228	5	sterane	sterane	NOUN
fnp-3528	228	6	derivative	derivative	ADJ
fnp-3528	228	7	ponasterone	ponasterone	NOUN
fnp-3528	228	8	a	a	DET
fnp-3528	228	9	(	(	PUNCT
fnp-3528	228	10	ecdysone	ecdysone	NOUN
fnp-3528	228	11	;	;	PUNCT
fnp-3528	228	12	abca1	abca1	NOUN
fnp-3528	228	13	protein	protein	NOUN
fnp-3528	228	14	;	;	PUNCT
fnp-3528	228	15	abca1	abca1	NOUN
fnp-3528	228	16	-	-	PUNCT
fnp-3528	228	17	mediated	mediate	VERB
fnp-3528	228	18	cholesterol	cholesterol	NOUN
fnp-3528	228	19	and	and	CCONJ
fnp-3528	228	20	phospholipid	phospholipid	NOUN
fnp-3528	228	21	transport),202	transport),202	PROPN
fnp-3528	228	22	and	and	CCONJ
fnp-3528	228	23	the	the	DET
fnp-3528	228	24	enoxolone	enoxolone	NOUN
fnp-3528	228	25	derivative	derivative	PROPN
fnp-3528	228	26	glycyrrhizine	glycyrrhizine	NOUN
fnp-3528	228	27	(	(	PUNCT
fnp-3528	228	28	abca1	abca1	NOUN
fnp-3528	228	29	protein).414	protein).414	NOUN
fnp-3528	228	30	in	in	ADP
fnp-3528	228	31	addition	addition	NOUN
fnp-3528	228	32	,	,	PUNCT
fnp-3528	228	33	the	the	DET
fnp-3528	228	34	sterane	sterane	NOUN
fnp-3528	228	35	derivative	derivative	NOUN
fnp-3528	228	36	and	and	CCONJ
fnp-3528	228	37	farnesoid	farnesoid	ADJ
fnp-3528	228	38	-	-	ADJ
fnp-3528	228	39	x	x	NOUN
fnp-3528	228	40	-	-	NOUN
fnp-3528	228	41	receptor	receptor	NOUN
fnp-3528	228	42	(	(	PUNCT
fnp-3528	228	43	fxr	fxr	NOUN
fnp-3528	228	44	)	)	PUNCT
fnp-3528	228	45	activator	activator	NOUN
fnp-3528	228	46	obeticholic	obeticholic	NOUN
fnp-3528	228	47	acid	acid	PROPN
fnp-3528	228	48	induced	induce	VERB
fnp-3528	228	49	abca1	abca1	PROPN
fnp-3528	228	50	mrna	mrna	PROPN
fnp-3528	228	51	levels	level	NOUN
fnp-3528	228	52	in	in	ADP
fnp-3528	228	53	vivo	vivo	NOUN
fnp-3528	228	54	in	in	ADP
fnp-3528	228	55	the	the	DET
fnp-3528	228	56	ileum	ileum	NOUN
fnp-3528	228	57	of	of	ADP
fnp-3528	228	58	srb1	srb1	PROPN
fnp-3528	228	59	-	-	PUNCT
fnp-3528	228	60	deficient	deficient	ADJ
fnp-3528	228	61	c57bl/6	c57bl/6	NOUN
fnp-3528	228	62	mice.415	mice.415	NOUN
fnp-3528	228	63	in	in	ADP
fnp-3528	228	64	thp-1	thp-1	ADP
fnp-3528	228	65	macrophages	macrophage	NOUN
fnp-3528	228	66	,	,	PUNCT
fnp-3528	228	67	the	the	DET
fnp-3528	228	68	sterane	sterane	NOUN
fnp-3528	228	69	-	-	PUNCT
fnp-3528	228	70	like	like	ADJ
fnp-3528	228	71	maslinic	maslinic	ADJ
fnp-3528	228	72	acid	acid	NOUN
fnp-3528	228	73	induced	induce	VERB
fnp-3528	228	74	abca1	abca1	PROPN
fnp-3528	228	75	mrna	mrna	PROPN
fnp-3528	228	76	levels	level	NOUN
fnp-3528	228	77	,	,	PUNCT
fnp-3528	228	78	paralleled	parallel	VERB
fnp-3528	228	79	with	with	ADP
fnp-3528	228	80	an	an	DET
fnp-3528	228	81	increased	increase	VERB
fnp-3528	228	82	cholesterol	cholesterol	NOUN
fnp-3528	228	83	efflux	efflux	NOUN
fnp-3528	228	84	from	from	ADP
fnp-3528	228	85	these	these	DET
fnp-3528	228	86	cells.390	cells.390	NOUN
fnp-3528	228	87	finally	finally	ADV
fnp-3528	228	88	,	,	PUNCT
fnp-3528	228	89	the	the	DET
fnp-3528	228	90	salvia	salvia	NOUN
fnp-3528	228	91	miltiorrhiza	miltiorrhiza	NOUN
fnp-3528	228	92	-	-	PUNCT
fnp-3528	228	93	derived	derive	VERB
fnp-3528	228	94	tanshindiol	tanshindiol	NOUN
fnp-3528	228	95	c	c	PROPN
fnp-3528	228	96	was	be	AUX
fnp-3528	228	97	demonstrated	demonstrate	VERB
fnp-3528	228	98	to	to	PART
fnp-3528	228	99	induce	induce	VERB
fnp-3528	228	100	peroxiredoxin	peroxiredoxin	PROPN
fnp-3528	228	101	1	1	NUM
fnp-3528	228	102	mrna	mrna	PROPN
fnp-3528	228	103	(	(	PUNCT
fnp-3528	228	104	prdx1	prdx1	X
fnp-3528	228	105	)	)	PUNCT
fnp-3528	228	106	and	and	CCONJ
fnp-3528	228	107	protein	protein	NOUN
fnp-3528	228	108	(	(	PUNCT
fnp-3528	228	109	prdx1	prdx1	NOUN
fnp-3528	228	110	)	)	PUNCT
fnp-3528	228	111	content	content	NOUN
fnp-3528	228	112	in	in	ADP
fnp-3528	228	113	murine	murine	ADJ
fnp-3528	228	114	raw264.7	raw264.7	ADJ
fnp-3528	228	115	cells.416	cells.416	PROPN
fnp-3528	228	116	prdx1	prdx1	PROPN
fnp-3528	228	117	was	be	AUX
fnp-3528	228	118	demonstrated	demonstrate	VERB
fnp-3528	228	119	to	to	PART
fnp-3528	228	120	regulate	regulate	VERB
fnp-3528	228	121	abca1	abca1	PROPN
fnp-3528	228	122	mrna	mrna	PROPN
fnp-3528	228	123	and	and	CCONJ
fnp-3528	228	124	abca1	abca1	NOUN
fnp-3528	228	125	protein	protein	NOUN
fnp-3528	228	126	expression	expression	NOUN
fnp-3528	228	127	.	.	PUNCT
fnp-3528	229	1	a	a	DET
fnp-3528	229	2	reduction	reduction	NOUN
fnp-3528	229	3	of	of	ADP
fnp-3528	229	4	intracellular	intracellular	ADJ
fnp-3528	229	5	cholesterol	cholesterol	NOUN
fnp-3528	229	6	levels	level	NOUN
fnp-3528	229	7	in	in	ADP
fnp-3528	229	8	murine	murine	ADJ
fnp-3528	229	9	peritoneal	peritoneal	ADJ
fnp-3528	229	10	macrophages	macrophage	NOUN
fnp-3528	229	11	could	could	AUX
fnp-3528	229	12	also	also	ADV
fnp-3528	229	13	be	be	AUX
fnp-3528	229	14	observed	observe	VERB
fnp-3528	229	15	.	.	PUNCT
fnp-3528	230	1	flavonoids	flavonoid	NOUN
fnp-3528	230	2	the	the	DET
fnp-3528	230	3	flavonoids	flavonoid	NOUN
fnp-3528	230	4	daidzein	daidzein	ADV
fnp-3528	230	5	(	(	PUNCT
fnp-3528	230	6	figure	figure	NOUN
fnp-3528	230	7	 	 	SPACE
fnp-3528	230	8	2),309	2),309	NUM
fnp-3528	230	9	kaempferol,397	kaempferol,397	NOUN
fnp-3528	230	10	and	and	CCONJ
fnp-3528	230	11	pratensein309	pratensein309	PROPN
fnp-3528	230	12	induced	induced	ADJ
fnp-3528	230	13	abca1	abca1	NOUN
fnp-3528	230	14	mrna309,397	mrna309,397	NOUN
fnp-3528	230	15	and	and	CCONJ
fnp-3528	230	16	abca1	abca1	NOUN
fnp-3528	230	17	protein	protein	NOUN
fnp-3528	230	18	levels309	levels309	PROPN
fnp-3528	230	19	as	as	ADV
fnp-3528	230	20	well	well	ADV
fnp-3528	230	21	as	as	ADP
fnp-3528	230	22	abca1	abca1	NOUN
fnp-3528	230	23	-	-	PUNCT
fnp-3528	230	24	mediated	mediate	VERB
fnp-3528	230	25	cholesterol	cholesterol	NOUN
fnp-3528	230	26	efflux.397	efflux.397	ADJ
fnp-3528	230	27	in	in	ADP
fnp-3528	230	28	addition	addition	NOUN
fnp-3528	230	29	,	,	PUNCT
fnp-3528	230	30	hesperetin-7	hesperetin-7	NUM
fnp-3528	230	31	-	-	PUNCT
fnp-3528	230	32	o	o	NOUN
fnp-3528	230	33	-	-	NOUN
fnp-3528	230	34	rutinosid	rutinosid	NOUN
fnp-3528	230	35	(	(	PUNCT
fnp-3528	230	36	hesperidin	hesperidin	NOUN
fnp-3528	230	37	)	)	PUNCT
fnp-3528	230	38	abrogated	abrogate	VERB
fnp-3528	230	39	the	the	DET
fnp-3528	230	40	negative	negative	ADJ
fnp-3528	230	41	effect	effect	NOUN
fnp-3528	230	42	of	of	ADP
fnp-3528	230	43	varenicline	varenicline	NOUN
fnp-3528	230	44	on	on	ADP
fnp-3528	230	45	abca1	abca1	NOUN
fnp-3528	230	46	protein	protein	NOUN
fnp-3528	230	47	expression	expression	NOUN
fnp-3528	230	48	in	in	ADP
fnp-3528	230	49	raw264.7	raw264.7	PROPN
fnp-3528	230	50	macrophages.417	macrophages.417	VERB
fnp-3528	230	51	the	the	DET
fnp-3528	230	52	authors	author	NOUN
fnp-3528	230	53	could	could	AUX
fnp-3528	230	54	underpin	underpin	VERB
fnp-3528	230	55	their	their	PRON
fnp-3528	230	56	findings	finding	NOUN
fnp-3528	230	57	with	with	ADP
fnp-3528	230	58	a	a	DET
fnp-3528	230	59	reduction	reduction	NOUN
fnp-3528	230	60	of	of	ADP
fnp-3528	230	61	aortic	aortic	ADJ
fnp-3528	230	62	atherosclerotic	atherosclerotic	ADJ
fnp-3528	230	63	plaques	plaque	NOUN
fnp-3528	230	64	in	in	ADP
fnp-3528	230	65	apoe	apoe	ADJ
fnp-3528	230	66	knock	knock	NOUN
fnp-3528	230	67	-	-	PUNCT
fnp-3528	230	68	out	out	ADP
fnp-3528	230	69	c57bl/6	c57bl/6	NOUN
fnp-3528	230	70	mice	mouse	NOUN
fnp-3528	230	71	along	along	ADV
fnp-3528	230	72	with	with	ADP
fnp-3528	230	73	reduced	reduced	ADJ
fnp-3528	230	74	lipid	lipid	NOUN
fnp-3528	230	75	levels	level	NOUN
fnp-3528	230	76	in	in	ADP
fnp-3528	230	77	peritoneal	peritoneal	ADJ
fnp-3528	230	78	macrophages	macrophage	NOUN
fnp-3528	230	79	derived	derive	VERB
fnp-3528	230	80	from	from	ADP
fnp-3528	230	81	these	these	DET
fnp-3528	230	82	mice	mouse	NOUN
fnp-3528	230	83	.	.	PUNCT
fnp-3528	231	1	polyphenols	polyphenol	NOUN
fnp-3528	231	2	and	and	CCONJ
fnp-3528	231	3	polyphenol	polyphenol	NOUN
fnp-3528	231	4	-	-	PUNCT
fnp-3528	231	5	like	like	ADJ
fnp-3528	231	6	natural	natural	ADJ
fnp-3528	231	7	compounds	compound	NOUN
fnp-3528	231	8	several	several	ADJ
fnp-3528	231	9	polyphenols	polyphenol	NOUN
fnp-3528	231	10	and	and	CCONJ
fnp-3528	231	11	polyphenol	polyphenol	NOUN
fnp-3528	231	12	-	-	PUNCT
fnp-3528	231	13	like	like	ADJ
fnp-3528	231	14	compounds	compound	NOUN
fnp-3528	231	15	induced	induce	VERB
fnp-3528	231	16	abca1	abca1	NOUN
fnp-3528	231	17	mrna408,418	mrna408,418	NOUN
fnp-3528	231	18	and	and	CCONJ
fnp-3528	231	19	abca1	abca1	NOUN
fnp-3528	231	20	protein393,404	protein393,404	NOUN
fnp-3528	231	21	levels	level	NOUN
fnp-3528	231	22	in	in	ADP
fnp-3528	231	23	murine393,404,408,418	murine393,404,408,418	PROPN
fnp-3528	231	24	and	and	CCONJ
fnp-3528	231	25	human393	human393	PROPN
fnp-3528	231	26	macrophages	macrophage	NOUN
fnp-3528	231	27	,	,	PUNCT
fnp-3528	231	28	leading	lead	VERB
fnp-3528	231	29	to	to	ADP
fnp-3528	231	30	an	an	DET
fnp-3528	231	31	increased	increase	VERB
fnp-3528	231	32	cholesterol	cholesterol	NOUN
fnp-3528	231	33	efflux.404,408,418	efflux.404,408,418	NOUN
fnp-3528	231	34	these	these	PRON
fnp-3528	231	35	include	include	VERB
fnp-3528	231	36	certain	certain	ADJ
fnp-3528	231	37	cannabis	cannabis	NOUN
fnp-3528	231	38	sativa	sativa	NOUN
fnp-3528	231	39	-	-	PUNCT
fnp-3528	231	40	derived	derive	VERB
fnp-3528	231	41	stilbenoids404	stilbenoids404	PROPN
fnp-3528	231	42	as	as	ADV
fnp-3528	231	43	well	well	ADV
fnp-3528	231	44	as	as	ADP
fnp-3528	231	45	the	the	DET
fnp-3528	231	46	tadehagi	tadehagi	ADJ
fnp-3528	231	47	triquetrum	triquetrum	ADV
fnp-3528	231	48	-	-	PUNCT
fnp-3528	231	49	derived	derive	VERB
fnp-3528	231	50	phenylpropanoid	phenylpropanoid	NOUN
fnp-3528	231	51	glycosides	glycoside	NOUN
fnp-3528	231	52	urolithin	urolithin	PROPN
fnp-3528	231	53	a418	a418	PROPN
fnp-3528	231	54	and	and	CCONJ
fnp-3528	231	55	urolithin	urolithin	PROPN
fnp-3528	231	56	b	b	PROPN
fnp-3528	231	57	(	(	PUNCT
fnp-3528	231	58	sulfate).393	sulfate).393	ADJ
fnp-3528	231	59	in	in	ADP
fnp-3528	231	60	vivo	vivo	NOUN
fnp-3528	231	61	,	,	PUNCT
fnp-3528	231	62	atherosclerotic	atherosclerotic	ADJ
fnp-3528	231	63	plaques	plaque	NOUN
fnp-3528	231	64	were	be	AUX
fnp-3528	231	65	reduced	reduce	VERB
fnp-3528	231	66	after	after	ADP
fnp-3528	231	67	urolothin	urolothin	PROPN
fnp-3528	231	68	b	b	PROPN
fnp-3528	231	69	treatment	treatment	NOUN
fnp-3528	231	70	.	.	PUNCT
fnp-3528	232	1	one	one	NUM
fnp-3528	232	2	phenylpropanoid	phenylpropanoid	NOUN
fnp-3528	232	3	glycoside	glycoside	NOUN
fnp-3528	232	4	was	be	AUX
fnp-3528	232	5	demonstrated	demonstrate	VERB
fnp-3528	232	6	to	to	PART
fnp-3528	232	7	increase	increase	VERB
fnp-3528	232	8	lxra	lxra	NOUN
fnp-3528	232	9	,	,	PUNCT
fnp-3528	232	10	but	but	CCONJ
fnp-3528	232	11	none	none	NOUN
fnp-3528	232	12	of	of	ADP
fnp-3528	232	13	the	the	DET
fnp-3528	232	14	other	other	ADJ
fnp-3528	232	15	compounds	compound	NOUN
fnp-3528	232	16	could	could	AUX
fnp-3528	232	17	confirm	confirm	VERB
fnp-3528	232	18	these	these	DET
fnp-3528	232	19	results	result	NOUN
fnp-3528	232	20	.	.	PUNCT
fnp-3528	233	1	given	give	VERB
fnp-3528	233	2	that	that	SCONJ
fnp-3528	233	3	the	the	DET
fnp-3528	233	4	effect	effect	NOUN
fnp-3528	233	5	of	of	ADP
fnp-3528	233	6	all	all	DET
fnp-3528	233	7	compounds	compound	NOUN
fnp-3528	233	8	on	on	ADP
fnp-3528	233	9	abca1	abca1	NOUN
fnp-3528	233	10	expression	expression	NOUN
fnp-3528	233	11	was	be	AUX
fnp-3528	233	12	similar	similar	ADJ
fnp-3528	233	13	,	,	PUNCT
fnp-3528	233	14	it	it	PRON
fnp-3528	233	15	is	be	AUX
fnp-3528	233	16	likely	likely	ADJ
fnp-3528	233	17	that	that	SCONJ
fnp-3528	233	18	another	another	PRON
fnp-3528	233	19	,	,	PUNCT
fnp-3528	233	20	yet	yet	CCONJ
fnp-3528	233	21	unknown	unknown	ADJ
fnp-3528	233	22	pathway	pathway	NOUN
fnp-3528	233	23	was	be	AUX
fnp-3528	233	24	the	the	DET
fnp-3528	233	25	major	major	ADJ
fnp-3528	233	26	contributor	contributor	NOUN
fnp-3528	233	27	to	to	ADP
fnp-3528	233	28	the	the	DET
fnp-3528	233	29	observed	observed	ADJ
fnp-3528	233	30	effects	effect	NOUN
fnp-3528	233	31	.	.	PUNCT
fnp-3528	234	1	other	other	ADJ
fnp-3528	234	2	natural	natural	ADJ
fnp-3528	234	3	compounds	compound	NOUN
fnp-3528	234	4	sodium	sodium	NOUN
fnp-3528	234	5	butyrate	butyrate	NOUN
fnp-3528	234	6	induced	induce	VERB
fnp-3528	234	7	abca1	abca1	NOUN
fnp-3528	234	8	mrna	mrna	PROPN
fnp-3528	234	9	and	and	CCONJ
fnp-3528	234	10	abca1	abca1	NOUN
fnp-3528	234	11	protein	protein	NOUN
fnp-3528	234	12	levels	level	NOUN
fnp-3528	234	13	in	in	ADP
fnp-3528	234	14	murine	murine	ADJ
fnp-3528	234	15	raw264.7	raw264.7	NOUN
fnp-3528	234	16	cells	cell	NOUN
fnp-3528	234	17	,	,	PUNCT
fnp-3528	234	18	accompanied	accompany	VERB
fnp-3528	234	19	by	by	ADP
fnp-3528	234	20	an	an	DET
fnp-3528	234	21	increased	increase	VERB
fnp-3528	234	22	efflux	efflux	NOUN
fnp-3528	234	23	of	of	ADP
fnp-3528	234	24	cholesterol	cholesterol	NOUN
fnp-3528	234	25	from	from	ADP
fnp-3528	234	26	these	these	DET
fnp-3528	234	27	cells.419	cells.419	PROPN
fnp-3528	234	28	this	this	DET
fnp-3528	234	29	induction	induction	NOUN
fnp-3528	234	30	was	be	AUX
fnp-3528	234	31	reflected	reflect	VERB
fnp-3528	234	32	by	by	ADP
fnp-3528	234	33	increased	increase	VERB
fnp-3528	234	34	abca1	abca1	NOUN
fnp-3528	234	35	protein	protein	NOUN
fnp-3528	234	36	content	content	NOUN
fnp-3528	234	37	in	in	ADP
fnp-3528	234	38	vivo	vivo	NOUN
fnp-3528	234	39	,	,	PUNCT
fnp-3528	234	40	reduced	reduce	VERB
fnp-3528	234	41	plasma	plasma	NOUN
fnp-3528	234	42	cholesterol	cholesterol	NOUN
fnp-3528	234	43	and	and	CCONJ
fnp-3528	234	44	triglyceride	triglyceride	ADJ
fnp-3528	234	45	levels	level	NOUN
fnp-3528	234	46	,	,	PUNCT
fnp-3528	234	47	and	and	CCONJ
fnp-3528	234	48	reduced	reduce	VERB
fnp-3528	234	49	aortic	aortic	ADJ
fnp-3528	234	50	atherosclerotic	atherosclerotic	ADJ
fnp-3528	234	51	lesions	lesion	NOUN
fnp-3528	234	52	and	and	CCONJ
fnp-3528	234	53	hepatic	hepatic	ADJ
fnp-3528	234	54	steatosis	steatosis	NOUN
fnp-3528	234	55	in	in	ADP
fnp-3528	234	56	high	high	ADJ
fnp-3528	234	57	fat	fat	ADJ
fnp-3528	234	58	diet	diet	NOUN
fnp-3528	234	59	-	-	PUNCT
fnp-3528	234	60	fed	feed	VERB
fnp-3528	234	61	apoe	apoe	ADJ
fnp-3528	234	62	knock	knock	NOUN
fnp-3528	234	63	-	-	PUNCT
fnp-3528	234	64	out	out	ADP
fnp-3528	234	65	c57bl/6	c57bl/6	NOUN
fnp-3528	234	66	mice	mouse	NOUN
fnp-3528	234	67	.	.	PUNCT
fnp-3528	235	1	pharmacological	pharmacological	ADJ
fnp-3528	235	2	drugs	drug	NOUN
fnp-3528	235	3	several	several	ADJ
fnp-3528	235	4	pharmacological	pharmacological	ADJ
fnp-3528	235	5	drugs	drug	NOUN
fnp-3528	235	6	induced	induce	VERB
fnp-3528	235	7	abcb1	abcb1	NOUN
fnp-3528	235	8	/	/	SYM
fnp-3528	235	9	abca1	abca1	NOUN
fnp-3528	235	10	mrna309,420,421	mrna309,420,421	NOUN
fnp-3528	235	11	and	and	CCONJ
fnp-3528	235	12	abca1	abca1	NOUN
fnp-3528	235	13	protein,309,391,421	protein,309,391,421	ADP
fnp-3528	235	14	including	include	VERB
fnp-3528	235	15	the	the	DET
fnp-3528	235	16	anti	anti	ADJ
fnp-3528	235	17	-	-	ADJ
fnp-3528	235	18	obesity	obesity	ADJ
fnp-3528	235	19	drug	drug	NOUN
fnp-3528	235	20	orlistat,391	orlistat,391	PROPN
fnp-3528	235	21	the	the	DET
fnp-3528	235	22	antibiotic	antibiotic	ADJ
fnp-3528	235	23	sulfoxaflor,420	sulfoxaflor,420	X
fnp-3528	236	1	the	the	DET
fnp-3528	236	2	leukotriene	leukotriene	NOUN
fnp-3528	236	3	receptor	receptor	NOUN
fnp-3528	236	4	antagonist	antagonist	NOUN
fnp-3528	236	5	zafirlukast,421	zafirlukast,421	NOUN
fnp-3528	236	6	as	as	ADV
fnp-3528	236	7	well	well	ADV
fnp-3528	236	8	as	as	ADP
fnp-3528	236	9	the	the	DET
fnp-3528	236	10	anthracyclines	anthracycline	NOUN
fnp-3528	236	11	aclarubicin309	aclarubicin309	PROPN
fnp-3528	236	12	and	and	CCONJ
fnp-3528	236	13	pyrromycin.309	pyrromycin.309	PROPN
fnp-3528	236	14	zafirlukast	zafirlukast	NOUN
fnp-3528	236	15	in	in	ADP
fnp-3528	236	16	particular	particular	ADJ
fnp-3528	236	17	reduced	reduce	VERB
fnp-3528	236	18	intracellular	intracellular	ADJ
fnp-3528	236	19	cholesterol	cholesterol	NOUN
fnp-3528	236	20	and	and	CCONJ
fnp-3528	236	21	lipid	lipid	NOUN
fnp-3528	236	22	content	content	NOUN
fnp-3528	236	23	in	in	ADP
fnp-3528	236	24	oxidized	oxidized	ADJ
fnp-3528	236	25	ldl-(oxldl)-induced	ldl-(oxldl)-induce	VERB
fnp-3528	236	26	lipid	lipid	NOUN
fnp-3528	236	27	-	-	PUNCT
fnp-3528	236	28	overloaded	overload	VERB
fnp-3528	236	29	raw264.7	raw264.7	NOUN
fnp-3528	236	30	macrophages	macrophage	NOUN
fnp-3528	236	31	,	,	PUNCT
fnp-3528	236	32	and	and	CCONJ
fnp-3528	236	33	increased	increase	VERB
fnp-3528	236	34	cholesterol	cholesterol	NOUN
fnp-3528	236	35	efflux	efflux	NOUN
fnp-3528	236	36	from	from	ADP
fnp-3528	236	37	these	these	DET
fnp-3528	236	38	cells.421	cells.421	NOUN
fnp-3528	236	39	finally	finally	ADV
fnp-3528	236	40	,	,	PUNCT
fnp-3528	236	41	it	it	PRON
fnp-3528	236	42	should	should	AUX
fnp-3528	236	43	be	be	AUX
fnp-3528	236	44	highlighted	highlight	VERB
fnp-3528	236	45	that	that	SCONJ
fnp-3528	236	46	mifepristone	mifepristone	NOUN
fnp-3528	236	47	has	have	AUX
fnp-3528	236	48	frequently	frequently	ADV
fnp-3528	236	49	been	be	AUX
fnp-3528	236	50	used	use	VERB
fnp-3528	236	51	in	in	ADP
fnp-3528	236	52	a	a	DET
fnp-3528	236	53	mifepristone	mifepristone	NOUN
fnp-3528	236	54	-	-	PUNCT
fnp-3528	236	55	inducible	inducible	ADJ
fnp-3528	236	56	transfection	transfection	NOUN
fnp-3528	236	57	system	system	NOUN
fnp-3528	236	58	to	to	PART
fnp-3528	236	59	stabilize	stabilize	VERB
fnp-3528	236	60	and	and	CCONJ
fnp-3528	236	61	increase	increase	VERB
fnp-3528	236	62	abca1	abca1	NOUN
fnp-3528	236	63	expression	expression	NOUN
fnp-3528	236	64	in	in	ADP
fnp-3528	236	65	abca1	abca1	NOUN
fnp-3528	236	66	-	-	PUNCT
fnp-3528	236	67	transfected	transfecte	VERB
fnp-3528	236	68	baby	baby	NOUN
fnp-3528	236	69	hamster	hamster	NOUN
fnp-3528	236	70	kidney	kidney	NOUN
fnp-3528	236	71	(	(	PUNCT
fnp-3528	236	72	bhk)-21	bhk)-21	PROPN
fnp-3528	236	73	cells	cell	NOUN
fnp-3528	236	74	.	.	PUNCT
fnp-3528	237	1	this	this	DET
fnp-3528	237	2	abca1	abca1	NOUN
fnp-3528	237	3	induction	induction	NOUN
fnp-3528	237	4	could	could	AUX
fnp-3528	237	5	be	be	AUX
fnp-3528	237	6	functionally	functionally	ADV
fnp-3528	237	7	confirmed	confirm	VERB
fnp-3528	237	8	by	by	ADP
fnp-3528	237	9	increased	increase	VERB
fnp-3528	237	10	abca1	abca1	NOUN
fnp-3528	237	11	-	-	PUNCT
fnp-3528	237	12	mediated	mediate	VERB
fnp-3528	237	13	cholesterol	cholesterol	NOUN
fnp-3528	237	14	and	and	CCONJ
fnp-3528	237	15	phospholipid	phospholipid	NOUN
fnp-3528	237	16	efflux.245,273,422	efflux.245,273,422	NOUN
fnp-3528	237	17	synthetic	synthetic	ADJ
fnp-3528	237	18	compounds	compound	NOUN
fnp-3528	237	19	,	,	PUNCT
fnp-3528	237	20	hts	hts	PROPN
fnp-3528	237	21	hits	hit	VERB
fnp-3528	237	22	,	,	PUNCT
fnp-3528	237	23	and	and	CCONJ
fnp-3528	237	24	synthetic	synthetic	ADJ
fnp-3528	237	25	approaches	approach	VERB
fnp-3528	237	26	the	the	DET
fnp-3528	237	27	purinergic	purinergic	NOUN
fnp-3528	237	28	p2y7	p2y7	VERB
fnp-3528	237	29	receptor	receptor	NOUN
fnp-3528	237	30	antagonists	antagonist	NOUN
fnp-3528	237	31	az-1	az-1	NOUN
fnp-3528	237	32	,	,	PUNCT
fnp-3528	237	33	az-2	az-2	ADV
fnp-3528	237	34	,	,	PUNCT
fnp-3528	237	35	and	and	CCONJ
fnp-3528	237	36	az10606120	az10606120	ADJ
fnp-3528	237	37	increased	increase	VERB
fnp-3528	237	38	abca1	abca1	NOUN
fnp-3528	237	39	mrna	mrna	PROPN
fnp-3528	237	40	and	and	CCONJ
fnp-3528	237	41	abca1	abca1	NOUN
fnp-3528	237	42	protein	protein	NOUN
fnp-3528	237	43	levels	level	NOUN
fnp-3528	237	44	and	and	CCONJ
fnp-3528	237	45	resulted	result	VERB
fnp-3528	237	46	in	in	ADP
fnp-3528	237	47	enhanced	enhanced	ADJ
fnp-3528	237	48	cholesterol	cholesterol	NOUN
fnp-3528	237	49	efflux	efflux	NOUN
fnp-3528	237	50	from	from	ADP
fnp-3528	237	51	human	human	ADJ
fnp-3528	237	52	ccfsttg1	ccfsttg1	PROPN
fnp-3528	237	53	astrocytoma	astrocytoma	PROPN
fnp-3528	237	54	cells.423	cells.423	ADP
fnp-3528	237	55	the	the	DET
fnp-3528	237	56	polychlorinated	polychlorinate	VERB
fnp-3528	237	57	biphenyl	biphenyl	NOUN
fnp-3528	237	58	quinone	quinone	NOUN
fnp-3528	237	59	2,3,5	2,3,5	NUM
fnp-3528	237	60	-	-	NUM
fnp-3528	237	61	trichloro-6	trichloro-6	NUM
fnp-3528	237	62	-	-	PUNCT
fnp-3528	237	63	phenyl-[1,4]-benzo	phenyl-[1,4]-benzo	NOUN
fnp-3528	237	64	-	-	PUNCT
fnp-3528	237	65	quinone	quinone	NOUN
fnp-3528	237	66	(	(	PUNCT
fnp-3528	237	67	pcb29	pcb29	NOUN
fnp-3528	237	68	-	-	NOUN
fnp-3528	237	69	pq)424	pq)424	PROPN
fnp-3528	237	70	and	and	CCONJ
fnp-3528	237	71	the	the	DET
fnp-3528	237	72	fluorescigenic	fluorescigenic	ADJ
fnp-3528	237	73	pyrazoline	pyrazoline	NOUN
fnp-3528	237	74	derivative	derivative	NOUN
fnp-3528	237	75	5	5	NUM
fnp-3528	237	76	(	(	PUNCT
fnp-3528	237	77	fpd5)425	fpd5)425	PROPN
fnp-3528	237	78	increased	increase	VERB
fnp-3528	237	79	abca1	abca1	NOUN
fnp-3528	237	80	mrna424	mrna424	PROPN
fnp-3528	237	81	and	and	CCONJ
fnp-3528	237	82	abca1	abca1	PROPN
fnp-3528	237	83	protein425	protein425	PROPN
fnp-3528	237	84	content	content	NOUN
fnp-3528	237	85	in	in	ADP
fnp-3528	237	86	raw264.7	raw264.7	PROPN
fnp-3528	237	87	macrophages	macrophage	NOUN
fnp-3528	237	88	and	and	CCONJ
fnp-3528	237	89	reduced	reduce	VERB
fnp-3528	237	90	cholesterol	cholesterol	NOUN
fnp-3528	237	91	content	content	NOUN
fnp-3528	237	92	in	in	ADP
fnp-3528	237	93	these	these	DET
fnp-3528	237	94	cells.424,425	cells.424,425	NOUN
fnp-3528	237	95	in	in	ADP
fnp-3528	237	96	vivo	vivo	NOUN
fnp-3528	237	97	,	,	PUNCT
fnp-3528	237	98	fpd5	fpd5	PROPN
fnp-3528	237	99	reduced	reduce	VERB
fnp-3528	237	100	aortic	aortic	ADJ
fnp-3528	237	101	lipid	lipid	NOUN
fnp-3528	237	102	and	and	CCONJ
fnp-3528	237	103	cholesterol	cholesterol	NOUN
fnp-3528	237	104	content	content	NOUN
fnp-3528	237	105	and	and	CCONJ
fnp-3528	237	106	atherosclerotic	atherosclerotic	ADJ
fnp-3528	237	107	lesions	lesion	NOUN
fnp-3528	237	108	in	in	ADP
fnp-3528	237	109	apoe	apoe	ADJ
fnp-3528	237	110	knock	knock	NOUN
fnp-3528	237	111	-	-	PUNCT
fnp-3528	237	112	out	out	ADP
fnp-3528	237	113	c57bl/6	c57bl/6	NOUN
fnp-3528	237	114	mice	mouse	NOUN
fnp-3528	237	115	.	.	PUNCT
fnp-3528	238	1	inducers	inducer	NOUN
fnp-3528	238	2	of	of	ADP
fnp-3528	238	3	other	other	ADJ
fnp-3528	238	4	abca	abca	NOUN
fnp-3528	238	5	transporters	transporter	NOUN
fnp-3528	238	6	abca2	abca2	ADV
fnp-3528	238	7	and	and	CCONJ
fnp-3528	238	8	abca3	abca3	PROPN
fnp-3528	238	9	as	as	SCONJ
fnp-3528	238	10	detailed	detailed	ADJ
fnp-3528	238	11	above	above	ADV
fnp-3528	238	12	,	,	PUNCT
fnp-3528	238	13	abca2	abca2	NOUN
fnp-3528	238	14	and	and	CCONJ
fnp-3528	238	15	abca3	abca3	PROPN
fnp-3528	238	16	are	be	AUX
fnp-3528	238	17	believed	believe	VERB
fnp-3528	238	18	to	to	PART
fnp-3528	238	19	contribute	contribute	VERB
fnp-3528	238	20	to	to	PART
fnp-3528	238	21	multidrug	multidrug	VERB
fnp-3528	238	22	resistance	resistance	NOUN
fnp-3528	238	23	in	in	ADP
fnp-3528	238	24	cancer.171,232	cancer.171,232	PROPN
fnp-3528	238	25	-	-	PUNCT
fnp-3528	238	26	239,241,242	239,241,242	NUM
fnp-3528	238	27	in	in	ADP
fnp-3528	238	28	human	human	ADJ
fnp-3528	238	29	k562	k562	PROPN
fnp-3528	238	30	leukemia	leukemia	NOUN
fnp-3528	238	31	cells	cell	NOUN
fnp-3528	238	32	,	,	PUNCT
fnp-3528	238	33	it	it	PRON
fnp-3528	238	34	was	be	AUX
fnp-3528	238	35	demonstrated	demonstrate	VERB
fnp-3528	238	36	that	that	SCONJ
fnp-3528	238	37	the	the	DET
fnp-3528	238	38	tyrosine	tyrosine	NOUN
fnp-3528	238	39	kinase	kinase	PROPN
fnp-3528	238	40	inhibitor	inhibitor	PROPN
fnp-3528	238	41	(	(	PUNCT
fnp-3528	238	42	tki	tki	NOUN
fnp-3528	238	43	)	)	PUNCT
fnp-3528	238	44	imatinib	imatinib	NOUN
fnp-3528	238	45	induced	induce	VERB
fnp-3528	238	46	increased	increase	VERB
fnp-3528	238	47	levels	level	NOUN
fnp-3528	238	48	of	of	ADP
fnp-3528	238	49	abca2	abca2	PROPN
fnp-3528	238	50	mrna	mrna	PROPN
fnp-3528	238	51	and	and	CCONJ
fnp-3528	238	52	abca2	abca2	NOUN
fnp-3528	238	53	protein.236	protein.236	ADJ
fnp-3528	238	54	furthermore	furthermore	ADV
fnp-3528	238	55	,	,	PUNCT
fnp-3528	238	56	the	the	DET
fnp-3528	238	57	tkis	tkis	PROPN
fnp-3528	238	58	dasatinib	dasatinib	NOUN
fnp-3528	238	59	,	,	PUNCT
fnp-3528	238	60	imatinib	imatinib	NOUN
fnp-3528	238	61	,	,	PUNCT
fnp-3528	238	62	and	and	CCONJ
fnp-3528	238	63	nilotinib	nilotinib	NOUN
fnp-3528	238	64	increased	increase	VERB
fnp-3528	238	65	abca3	abca3	PROPN
fnp-3528	239	1	mrna	mrna	PROPN
fnp-3528	239	2	levels	level	NOUN
fnp-3528	239	3	in	in	ADP
fnp-3528	239	4	various	various	ADJ
fnp-3528	239	5	cancer	cancer	NOUN
fnp-3528	239	6	cell	cell	NOUN
fnp-3528	239	7	lines	line	NOUN
fnp-3528	239	8	as	as	ADV
fnp-3528	239	9	well	well	ADV
fnp-3528	239	10	as	as	ADP
fnp-3528	239	11	in	in	ADP
fnp-3528	239	12	tki	tki	NOUN
fnp-3528	239	13	-	-	ADJ
fnp-3528	239	14	treated	treat	VERB
fnp-3528	239	15	leukemia	leukemia	NOUN
fnp-3528	239	16	patients.426	patients.426	NOUN
fnp-3528	239	17	the	the	DET
fnp-3528	239	18	antimetabolite	antimetabolite	ADJ
fnp-3528	239	19	5	5	NUM
fnp-3528	239	20	-	-	PUNCT
fnp-3528	239	21	fluorouracil	fluorouracil	NOUN
fnp-3528	239	22	(	(	PUNCT
fnp-3528	239	23	5	5	NUM
fnp-3528	239	24	-	-	PUNCT
fnp-3528	239	25	fu	fu	NOUN
fnp-3528	239	26	)	)	PUNCT
fnp-3528	239	27	induced	induced	ADJ
fnp-3528	239	28	expression	expression	NOUN
fnp-3528	239	29	of	of	ADP
fnp-3528	239	30	abca3	abca3	PROPN
fnp-3528	239	31	mrna	mrna	PROPN
fnp-3528	239	32	in	in	ADP
fnp-3528	239	33	a	a	DET
fnp-3528	239	34	cholangiocarcinoma	cholangiocarcinoma	ADJ
fnp-3528	239	35	cell	cell	NOUN
fnp-3528	239	36	line,427	line,427	PROPN
fnp-3528	239	37	and	and	CCONJ
fnp-3528	239	38	methotrexate	methotrexate	NOUN
fnp-3528	239	39	increased	increase	VERB
fnp-3528	239	40	abca2	abca2	NOUN
fnp-3528	239	41	and	and	CCONJ
fnp-3528	239	42	abca3	abca3	PROPN
fnp-3528	239	43	mrna	mrna	PROPN
fnp-3528	239	44	in	in	ADP
fnp-3528	239	45	a	a	DET
fnp-3528	239	46	leukemia	leukemia	NOUN
fnp-3528	239	47	cell	cell	NOUN
fnp-3528	239	48	line.242	line.242	NOUN
fnp-3528	239	49	finally	finally	ADV
fnp-3528	239	50	,	,	PUNCT
fnp-3528	239	51	the	the	DET
fnp-3528	239	52	steroid	steroid	NOUN
fnp-3528	239	53	hormone	hormone	NOUN
fnp-3528	239	54	progesterone,179	progesterone,179	VERB
fnp-3528	239	55	the	the	DET
fnp-3528	239	56	antibiotic	antibiotic	ADJ
fnp-3528	239	57	sulfoxaflor,420	sulfoxaflor,420	NOUN
fnp-3528	239	58	and	and	CCONJ
fnp-3528	239	59	the	the	DET
fnp-3528	239	60	endosomal	endosomal	ADJ
fnp-3528	239	61	cholesterol	cholesterol	NOUN
fnp-3528	239	62	transport	transport	NOUN
fnp-3528	239	63	inhibitor	inhibitor	NOUN
fnp-3528	239	64	u18666a179	u18666a179	NOUN
fnp-3528	239	65	induced	induce	VERB
fnp-3528	239	66	abca2/	abca2/	PROPN
fnp-3528	239	67	abca2	abca2	NOUN
fnp-3528	240	1	transcripts420	transcripts420	PROPN
fnp-3528	240	2	in	in	ADP
fnp-3528	240	3	aphis	aphis	PROPN
fnp-3528	240	4	gossypii420	gossypii420	PROPN
fnp-3528	240	5	as	as	ADV
fnp-3528	240	6	well	well	ADV
fnp-3528	240	7	as	as	ADP
fnp-3528	240	8	in	in	ADP
fnp-3528	240	9	abca2	abca2	NOUN
fnp-3528	240	10	-	-	PUNCT
fnp-3528	240	11	transfected	transfecte	VERB
fnp-3528	240	12	chinese	chinese	ADJ
fnp-3528	240	13	hamster	hamster	NOUN
fnp-3528	240	14	ovary	ovary	NOUN
fnp-3528	240	15	(	(	PUNCT
fnp-3528	240	16	cho	cho	ADJ
fnp-3528	240	17	)	)	PUNCT
fnp-3528	240	18	cells	cell	NOUN
fnp-3528	240	19	and	and	CCONJ
fnp-3528	240	20	hepg2	hepg2	NOUN
fnp-3528	240	21	cells179	cells179	NOUN
fnp-3528	240	22	abca5	abca5	NOUN
fnp-3528	240	23	and	and	CCONJ
fnp-3528	240	24	abca6	abca6	NOUN
fnp-3528	240	25	as	as	SCONJ
fnp-3528	240	26	discussed	discuss	VERB
fnp-3528	240	27	earlier	early	ADV
fnp-3528	240	28	,	,	PUNCT
fnp-3528	240	29	cholesterol	cholesterol	NOUN
fnp-3528	240	30	and	and	CCONJ
fnp-3528	240	31	its	its	PRON
fnp-3528	240	32	derivatives	derivative	NOUN
fnp-3528	240	33	have	have	AUX
fnp-3528	240	34	been	be	AUX
fnp-3528	240	35	shown	show	VERB
fnp-3528	240	36	to	to	PART
fnp-3528	240	37	induce	induce	VERB
fnp-3528	240	38	abca1	abca1	NOUN
fnp-3528	240	39	/	/	SYM
fnp-3528	240	40	abca1	abca1	NOUN
fnp-3528	240	41	mrna	mrna	PROPN
fnp-3528	240	42	and/or	and/or	CCONJ
fnp-3528	240	43	abca1	abca1	NOUN
fnp-3528	240	44	protein	protein	NOUN
fnp-3528	240	45	levels.122,205,249,252,259,262	levels.122,205,249,252,259,262	PROPN
fnp-3528	240	46	-	-	PUNCT
fnp-3528	240	47	264,268,277,278,305	264,268,277,278,305	NUM
fnp-3528	240	48	-	-	PUNCT
fnp-3528	240	49	315,319	315,319	NUM
fnp-3528	240	50	-	-	SYM
fnp-3528	240	51	328	328	NUM
fnp-3528	240	52	induction	induction	NOUN
fnp-3528	240	53	by	by	ADP
fnp-3528	240	54	cholesterol	cholesterol	NOUN
fnp-3528	240	55	has	have	AUX
fnp-3528	240	56	also	also	ADV
fnp-3528	240	57	been	be	AUX
fnp-3528	240	58	demonstrated	demonstrate	VERB
fnp-3528	240	59	for	for	ADP
fnp-3528	240	60	abca5	abca5	ADJ
fnp-3528	240	61	mrna	mrna	PROPN
fnp-3528	240	62	and	and	CCONJ
fnp-3528	240	63	abca5	abca5	ADJ
fnp-3528	240	64	protein	protein	NOUN
fnp-3528	240	65	levels	level	NOUN
fnp-3528	240	66	in	in	ADP
fnp-3528	240	67	raw264.7	raw264.7	PROPN
fnp-3528	240	68	macrophages.321	macrophages.321	NOUN
fnp-3528	240	69	this	this	DET
fnp-3528	240	70	effect	effect	NOUN
fnp-3528	240	71	relied	rely	VERB
fnp-3528	240	72	on	on	ADP
fnp-3528	240	73	the	the	DET
fnp-3528	240	74	induction	induction	NOUN
fnp-3528	240	75	of	of	ADP
fnp-3528	240	76	lxra	lxra	NOUN
fnp-3528	240	77	,	,	PUNCT
fnp-3528	240	78	lxrb	lxrb	NOUN
fnp-3528	240	79	,	,	PUNCT
fnp-3528	240	80	and	and	CCONJ
fnp-3528	240	81	pparg	pparg	NOUN
fnp-3528	240	82	.	.	PUNCT
fnp-3528	241	1	consequently	consequently	ADV
fnp-3528	241	2	,	,	PUNCT
fnp-3528	241	3	several	several	ADJ
fnp-3528	241	4	lxr	lxr	NOUN
fnp-3528	241	5	and	and	CCONJ
fnp-3528	241	6	ppar	ppar	NOUN
fnp-3528	241	7	agonists	agonist	NOUN
fnp-3528	241	8	increased	increase	VERB
fnp-3528	241	9	abca5	abca5	NOUN
fnp-3528	241	10	expression	expression	NOUN
fnp-3528	241	11	,	,	PUNCT
fnp-3528	241	12	including	include	VERB
fnp-3528	241	13	bezafibrate	bezafibrate	NOUN
fnp-3528	241	14	(	(	PUNCT
fnp-3528	241	15	ppar	ppar	NOUN
fnp-3528	241	16	-	-	PUNCT
fnp-3528	241	17	α	α	NOUN
fnp-3528	241	18	,	,	PUNCT
fnp-3528	241	19	ppar	ppar	NOUN
fnp-3528	241	20	-	-	PUNCT
fnp-3528	241	21	β	β	NOUN
fnp-3528	241	22	,	,	PUNCT
fnp-3528	241	23	and	and	CCONJ
fnp-3528	241	24	ppar	ppar	NOUN
fnp-3528	241	25	-	-	PUNCT
fnp-3528	241	26	γ	γ	X
fnp-3528	241	27	;	;	PUNCT
fnp-3528	241	28	abca5	abca5	X
fnp-3528	241	29	mrna	mrna	NOUN
fnp-3528	241	30	and	and	CCONJ
fnp-3528	241	31	abca5	abca5	ADJ
fnp-3528	241	32	protein	protein	NOUN
fnp-3528	241	33	)	)	PUNCT
fnp-3528	241	34	,	,	PUNCT
fnp-3528	241	35	gw3965	gw3965	PROPN
fnp-3528	241	36	(	(	PUNCT
fnp-3528	241	37	lxr	lxr	PROPN
fnp-3528	241	38	;	;	PUNCT
fnp-3528	241	39	abca5	abca5	X
fnp-3528	241	40	mrna	mrna	PROPN
fnp-3528	241	41	)	)	PUNCT
fnp-3528	241	42	,	,	PUNCT
fnp-3528	241	43	rosiglitazone	rosiglitazone	NOUN
fnp-3528	241	44	(	(	PUNCT
fnp-3528	241	45	ppar	ppar	NOUN
fnp-3528	241	46	-	-	PUNCT
fnp-3528	241	47	γ	γ	X
fnp-3528	241	48	;	;	PUNCT
fnp-3528	241	49	abca5	abca5	X
fnp-3528	241	50	mrna	mrna	PROPN
fnp-3528	241	51	)	)	PUNCT
fnp-3528	241	52	,	,	PUNCT
fnp-3528	241	53	and	and	CCONJ
fnp-3528	241	54	troglitazone	troglitazone	NOUN
fnp-3528	241	55	(	(	PUNCT
fnp-3528	241	56	ppar	ppar	NOUN
fnp-3528	241	57	-	-	PUNCT
fnp-3528	241	58	γ	γ	X
fnp-3528	241	59	;	;	PUNCT
fnp-3528	241	60	abca5	abca5	X
fnp-3528	241	61	mrna	mrna	PROPN
fnp-3528	241	62	)	)	PUNCT
fnp-3528	241	63	in	in	ADP
fnp-3528	241	64	murine	murine	ADJ
fnp-3528	241	65	raw264.7	raw264.7	PROPN
fnp-3528	241	66	macrophages.321	macrophages.321	PROPN
fnp-3528	241	67	in	in	ADP
fnp-3528	241	68	addition	addition	NOUN
fnp-3528	241	69	,	,	PUNCT
fnp-3528	241	70	the	the	DET
fnp-3528	241	71	hmg	hmg	NOUN
fnp-3528	241	72	-	-	PUNCT
fnp-3528	241	73	coa	coa	NOUN
fnp-3528	241	74	-	-	PUNCT
fnp-3528	241	75	reductase	reductase	NOUN
fnp-3528	241	76	inhibitor	inhibitor	NOUN
fnp-3528	241	77	atorvastatin	atorvastatin	NOUN
fnp-3528	241	78	increased	increase	VERB
fnp-3528	241	79	abca5	abca5	PROPN
fnp-3528	242	1	mrna	mrna	PROPN
fnp-3528	242	2	and	and	CCONJ
fnp-3528	242	3	abca5	abca5	NOUN
fnp-3528	242	4	protein	protein	NOUN
fnp-3528	242	5	levels.321	levels.321	NOUN
fnp-3528	242	6	interestingly	interestingly	ADV
fnp-3528	242	7	,	,	PUNCT
fnp-3528	242	8	the	the	DET
fnp-3528	242	9	abca1	abca1	NOUN
fnp-3528	242	10	inhibitor	inhibitor	NOUN
fnp-3528	242	11	tacrolimus245	tacrolimus245	PROPN
fnp-3528	242	12	showed	show	VERB
fnp-3528	242	13	induction	induction	NOUN
fnp-3528	242	14	of	of	ADP
fnp-3528	242	15	abca5	abca5	PROPN
fnp-3528	242	16	mrna	mrna	PROPN
fnp-3528	242	17	in	in	ADP
fnp-3528	242	18	human	human	ADJ
fnp-3528	242	19	brain	brain	NOUN
fnp-3528	242	20	microvascular	microvascular	NOUN
fnp-3528	242	21	endothelial	endothelial	NOUN
fnp-3528	242	22	cells.428	cells.428	NOUN
fnp-3528	242	23	the	the	DET
fnp-3528	242	24	hmg	hmg	NOUN
fnp-3528	242	25	-	-	PUNCT
fnp-3528	242	26	coa	coa	NOUN
fnp-3528	242	27	-	-	PUNCT
fnp-3528	242	28	reductase	reductase	NOUN
fnp-3528	242	29	inhibitors	inhibitor	NOUN
fnp-3528	242	30	lovastatin	lovastatin	NOUN
fnp-3528	242	31	and	and	CCONJ
fnp-3528	242	32	mevastatin	mevastatin	NOUN
fnp-3528	242	33	resulted	result	VERB
fnp-3528	242	34	in	in	ADP
fnp-3528	242	35	an	an	DET
fnp-3528	242	36	induction	induction	NOUN
fnp-3528	242	37	of	of	ADP
fnp-3528	242	38	abca6	abca6	PROPN
fnp-3528	242	39	mrna	mrna	PROPN
fnp-3528	242	40	in	in	ADP
fnp-3528	242	41	the	the	DET
fnp-3528	242	42	human	human	ADJ
fnp-3528	242	43	endothelial	endothelial	NOUN
fnp-3528	242	44	cell	cell	NOUN
fnp-3528	242	45	line	line	NOUN
fnp-3528	242	46	ea.hy926.429	ea.hy926.429	PROPN
fnp-3528	242	47	finally	finally	ADV
fnp-3528	242	48	,	,	PUNCT
fnp-3528	242	49	in	in	ADP
fnp-3528	242	50	an	an	DET
fnp-3528	242	51	abca12	abca12	NOUN
fnp-3528	242	52	pig	pig	NOUN
fnp-3528	242	53	model	model	NOUN
fnp-3528	242	54	of	of	ADP
fnp-3528	242	55	the	the	DET
fnp-3528	242	56	rare	rare	ADJ
fnp-3528	242	57	and	and	CCONJ
fnp-3528	242	58	lethal	lethal	ADJ
fnp-3528	242	59	skin	skin	NOUN
fnp-3528	242	60	disease	disease	NOUN
fnp-3528	242	61	harlequin	harlequin	PROPN
fnp-3528	242	62	ichthyosis	ichthyosis	NOUN
fnp-3528	242	63	,	,	PUNCT
fnp-3528	242	64	it	it	PRON
fnp-3528	242	65	was	be	AUX
fnp-3528	242	66	demonstrated	demonstrate	VERB
fnp-3528	242	67	that	that	SCONJ
fnp-3528	242	68	treatment	treatment	NOUN
fnp-3528	242	69	with	with	ADP
fnp-3528	242	70	the	the	DET
fnp-3528	242	71	synthetic	synthetic	ADJ
fnp-3528	242	72	retinoid	retinoid	NOUN
fnp-3528	242	73	acitretin	acitretin	NOUN
fnp-3528	242	74	leads	lead	VERB
fnp-3528	242	75	to	to	ADP
fnp-3528	242	76	a	a	DET
fnp-3528	242	77	compensatory	compensatory	ADJ
fnp-3528	242	78	induction	induction	NOUN
fnp-3528	242	79	of	of	ADP
fnp-3528	242	80	abca6	abca6	PROPN
fnp-3528	242	81	mrna.430	mrna.430	PROPN
fnp-3528	242	82	abca7	abca7	PROPN
fnp-3528	242	83	similarly	similarly	ADV
fnp-3528	242	84	to	to	ADP
fnp-3528	242	85	abca1,202	abca1,202	NOUN
fnp-3528	242	86	the	the	DET
fnp-3528	242	87	sterane	sterane	NOUN
fnp-3528	242	88	derivative	derivative	ADJ
fnp-3528	242	89	ponasterone	ponasterone	NOUN
fnp-3528	242	90	a	a	DET
fnp-3528	242	91	increased	increase	VERB
fnp-3528	242	92	both	both	CCONJ
fnp-3528	242	93	abca7	abca7	NOUN
fnp-3528	242	94	protein	protein	NOUN
fnp-3528	242	95	expression	expression	NOUN
fnp-3528	242	96	and	and	CCONJ
fnp-3528	242	97	abca7	abca7	NOUN
fnp-3528	242	98	-	-	PUNCT
fnp-3528	242	99	mediated	mediate	VERB
fnp-3528	242	100	transport	transport	NOUN
fnp-3528	242	101	,	,	PUNCT
fnp-3528	242	102	mainly	mainly	ADV
fnp-3528	242	103	of	of	ADP
fnp-3528	242	104	phospholipids	phospholipid	NOUN
fnp-3528	242	105	,	,	PUNCT
fnp-3528	242	106	but	but	CCONJ
fnp-3528	242	107	also	also	ADV
fnp-3528	242	108	of	of	ADP
fnp-3528	242	109	cholesterol	cholesterol	NOUN
fnp-3528	242	110	to	to	ADP
fnp-3528	242	111	a	a	DET
fnp-3528	242	112	small	small	ADJ
fnp-3528	242	113	extent.202	extent.202	PROPN
fnp-3528	242	114	hmg	hmg	NOUN
fnp-3528	242	115	-	-	PUNCT
fnp-3528	242	116	coa	coa	NOUN
fnp-3528	242	117	-	-	PUNCT
fnp-3528	242	118	reductase	reductase	NOUN
fnp-3528	242	119	inhibitors	inhibitor	NOUN
fnp-3528	242	120	were	be	AUX
fnp-3528	242	121	described	describe	VERB
fnp-3528	242	122	above	above	ADV
fnp-3528	242	123	to	to	PART
fnp-3528	242	124	interfere	interfere	VERB
fnp-3528	242	125	with	with	ADP
fnp-3528	242	126	abca1/	abca1/	NOUN
fnp-3528	242	127	abca1312,318,330,343,362,411	abca1312,318,330,343,362,411	VERB
fnp-3528	242	128	and	and	CCONJ
fnp-3528	242	129	abca5321	abca5321	PROPN
fnp-3528	242	130	expression	expression	NOUN
fnp-3528	242	131	.	.	PUNCT
fnp-3528	243	1	in	in	ADP
fnp-3528	243	2	addition	addition	NOUN
fnp-3528	243	3	,	,	PUNCT
fnp-3528	243	4	certain	certain	ADJ
fnp-3528	243	5	compounds	compound	NOUN
fnp-3528	243	6	were	be	AUX
fnp-3528	243	7	also	also	ADV
fnp-3528	243	8	demonstrated	demonstrate	VERB
fnp-3528	243	9	to	to	PART
fnp-3528	243	10	interfere	interfere	VERB
fnp-3528	243	11	with	with	ADP
fnp-3528	243	12	abca7	abca7	PROPN
fnp-3528	243	13	expression.205,431	expression.205,431	NOUN
fnp-3528	243	14	these	these	PRON
fnp-3528	243	15	include	include	VERB
fnp-3528	243	16	pravastatin205,431	pravastatin205,431	NOUN
fnp-3528	243	17	and	and	CCONJ
fnp-3528	243	18	rosuvastatin	rosuvastatin	ADJ
fnp-3528	243	19	(	(	PUNCT
fnp-3528	243	20	figure	figure	NOUN
fnp-3528	243	21	 	 	SPACE
fnp-3528	243	22	2).431	2).431	NOUN
fnp-3528	243	23	these	these	DET
fnp-3528	243	24	agents	agent	NOUN
fnp-3528	243	25	increased	increase	VERB
fnp-3528	243	26	abca7	abca7	PROPN
fnp-3528	243	27	mrna	mrna	PROPN
fnp-3528	243	28	and	and	CCONJ
fnp-3528	243	29	abca7	abca7	ADJ
fnp-3528	243	30	protein	protein	NOUN
fnp-3528	243	31	levels	level	NOUN
fnp-3528	243	32	in	in	ADP
fnp-3528	243	33	vitro,205,431	vitro,205,431	NOUN
fnp-3528	243	34	whilst	whilst	SCONJ
fnp-3528	243	35	pravastatin	pravastatin	NOUN
fnp-3528	243	36	had	have	VERB
fnp-3528	243	37	the	the	DET
fnp-3528	243	38	same	same	ADJ
fnp-3528	243	39	effects	effect	NOUN
fnp-3528	243	40	in	in	ADP
fnp-3528	243	41	vivo	vivo	NOUN
fnp-3528	243	42	in	in	ADP
fnp-3528	243	43	murine	murine	ADJ
fnp-3528	243	44	peritoneal	peritoneal	ADJ
fnp-3528	243	45	macrophages.431	macrophages.431	NOUN
fnp-3528	243	46	surprisingly	surprisingly	ADV
fnp-3528	243	47	,	,	PUNCT
fnp-3528	243	48	this	this	DET
fnp-3528	243	49	increase	increase	NOUN
fnp-3528	243	50	of	of	ADP
fnp-3528	243	51	abca7	abca7	PROPN
fnp-3528	243	52	mrna	mrna	PROPN
fnp-3528	243	53	and	and	CCONJ
fnp-3528	243	54	abca7	abca7	ADJ
fnp-3528	243	55	protein	protein	NOUN
fnp-3528	243	56	levels	level	NOUN
fnp-3528	243	57	was	be	AUX
fnp-3528	243	58	accompanied	accompany	VERB
fnp-3528	243	59	by	by	ADP
fnp-3528	243	60	a	a	DET
fnp-3528	243	61	downregulation	downregulation	NOUN
fnp-3528	243	62	of	of	ADP
fnp-3528	243	63	lxra	lxra	NOUN
fnp-3528	243	64	and	and	CCONJ
fnp-3528	243	65	upregulation	upregulation	NOUN
fnp-3528	243	66	of	of	ADP
fnp-3528	243	67	srebp2	srebp2	NOUN
fnp-3528	243	68	in	in	ADP
fnp-3528	243	69	vitro.431	vitro.431	NOUN
fnp-3528	243	70	functionally	functionally	ADV
fnp-3528	243	71	,	,	PUNCT
fnp-3528	243	72	pravastatin	pravastatin	NOUN
fnp-3528	243	73	and	and	CCONJ
fnp-3528	243	74	rosuvastatin	rosuvastatin	ADJ
fnp-3528	243	75	reduced	reduce	VERB
fnp-3528	243	76	intracellular	intracellular	ADJ
fnp-3528	243	77	cholesterol	cholesterol	NOUN
fnp-3528	243	78	content431	content431	PROPN
fnp-3528	243	79	and	and	CCONJ
fnp-3528	243	80	induced	induce	VERB
fnp-3528	243	81	phagocytosis	phagocytosis	NOUN
fnp-3528	243	82	in	in	ADP
fnp-3528	243	83	vitro	vitro	NOUN
fnp-3528	243	84	and	and	CCONJ
fnp-3528	243	85	in	in	ADP
fnp-3528	243	86	vivo.431	vivo.431	NOUN
fnp-3528	243	87	these	these	DET
fnp-3528	243	88	effects	effect	NOUN
fnp-3528	243	89	occurred	occur	VERB
fnp-3528	243	90	in	in	ADP
fnp-3528	243	91	response	response	NOUN
fnp-3528	243	92	to	to	ADP
fnp-3528	243	93	an	an	DET
fnp-3528	243	94	abca1	abca1	NOUN
fnp-3528	243	95	downregulation	downregulation	NOUN
fnp-3528	243	96	by	by	ADP
fnp-3528	243	97	hmg	hmg	NOUN
fnp-3528	243	98	-	-	PUNCT
fnp-3528	243	99	coa	coa	NOUN
fnp-3528	243	100	-	-	PUNCT
fnp-3528	243	101	reductase	reductase	NOUN
fnp-3528	243	102	inhibitors	inhibitor	NOUN
fnp-3528	243	103	as	as	SCONJ
fnp-3528	243	104	described	describe	VERB
fnp-3528	243	105	earlier.312,321,384,432,439,429	earlier.312,321,384,432,439,429	PROPN
fnp-3528	243	106	due	due	ADP
fnp-3528	243	107	to	to	ADP
fnp-3528	243	108	their	their	PRON
fnp-3528	243	109	functional	functional	ADJ
fnp-3528	243	110	similarity	similarity	NOUN
fnp-3528	243	111	,	,	PUNCT
fnp-3528	243	112	the	the	DET
fnp-3528	243	113	upregulation	upregulation	NOUN
fnp-3528	243	114	of	of	ADP
fnp-3528	243	115	abca7	abca7	PROPN
fnp-3528	243	116	could	could	AUX
fnp-3528	243	117	be	be	AUX
fnp-3528	243	118	a	a	DET
fnp-3528	243	119	compensatory	compensatory	ADJ
fnp-3528	243	120	mechanism	mechanism	NOUN
fnp-3528	243	121	to	to	PART
fnp-3528	243	122	counteract	counteract	VERB
fnp-3528	243	123	the	the	DET
fnp-3528	243	124	loss	loss	NOUN
fnp-3528	243	125	of	of	ADP
fnp-3528	243	126	abca1.198	abca1.198	NOUN
fnp-3528	243	127	similarly	similarly	ADV
fnp-3528	243	128	,	,	PUNCT
fnp-3528	243	129	the	the	DET
fnp-3528	243	130	observed	observe	VERB
fnp-3528	243	131	lxra	lxra	NOUN
fnp-3528	243	132	downand	downand	PROPN
fnp-3528	243	133	srebp	srebp	PROPN
fnp-3528	243	134	up	up	ADP
fnp-3528	243	135	-	-	PUNCT
fnp-3528	243	136	regulation	regulation	NOUN
fnp-3528	243	137	may	may	AUX
fnp-3528	243	138	be	be	AUX
fnp-3528	243	139	a	a	DET
fnp-3528	243	140	compensatory	compensatory	ADJ
fnp-3528	243	141	mechanism	mechanism	NOUN
fnp-3528	243	142	to	to	PART
fnp-3528	243	143	counteract	counteract	VERB
fnp-3528	243	144	the	the	DET
fnp-3528	243	145	loss	loss	NOUN
fnp-3528	243	146	of	of	ADP
fnp-3528	243	147	intracellular	intracellular	ADJ
fnp-3528	243	148	cholesterol	cholesterol	NOUN
fnp-3528	243	149	.	.	PUNCT
fnp-3528	244	1	finally	finally	ADV
fnp-3528	244	2	,	,	PUNCT
fnp-3528	244	3	as	as	SCONJ
fnp-3528	244	4	described	describe	VERB
fnp-3528	244	5	for	for	ADP
fnp-3528	244	6	abca1,422	abca1,422	ADJ
fnp-3528	244	7	exposure	exposure	NOUN
fnp-3528	244	8	of	of	ADP
fnp-3528	244	9	abca7	abca7	NOUN
fnp-3528	244	10	-	-	PUNCT
fnp-3528	244	11	transfected	transfecte	VERB
fnp-3528	244	12	bhk-21	bhk-21	NUM
fnp-3528	244	13	cells	cell	NOUN
fnp-3528	244	14	to	to	ADP
fnp-3528	244	15	mifepristone	mifepristone	NOUN
fnp-3528	244	16	increased	increase	VERB
fnp-3528	244	17	abca7	abca7	PROPN
fnp-3528	244	18	protein	protein	NOUN
fnp-3528	244	19	content	content	NOUN
fnp-3528	244	20	and	and	CCONJ
fnp-3528	244	21	abca7	abca7	NOUN
fnp-3528	244	22	-	-	PUNCT
fnp-3528	244	23	mediated	mediate	VERB
fnp-3528	244	24	transport	transport	NOUN
fnp-3528	244	25	of	of	ADP
fnp-3528	244	26	phospholipids	phospholipid	NOUN
fnp-3528	244	27	and	and	CCONJ
fnp-3528	244	28	,	,	PUNCT
fnp-3528	244	29	to	to	ADP
fnp-3528	244	30	a	a	DET
fnp-3528	244	31	much	much	ADV
fnp-3528	244	32	lesser	less	ADJ
fnp-3528	244	33	extent	extent	NOUN
fnp-3528	244	34	,	,	PUNCT
fnp-3528	244	35	of	of	ADP
fnp-3528	244	36	cholesterol.422	cholesterol.422	ADJ
fnp-3528	244	37	abca8	abca8	PROPN
fnp-3528	244	38	abca8	abca8	PROPN
fnp-3528	245	1	mrna	mrna	PROPN
fnp-3528	245	2	and	and	CCONJ
fnp-3528	245	3	abca8	abca8	NOUN
fnp-3528	245	4	protein	protein	NOUN
fnp-3528	245	5	content	content	NOUN
fnp-3528	245	6	were	be	AUX
fnp-3528	245	7	induced	induce	VERB
fnp-3528	245	8	by	by	ADP
fnp-3528	245	9	gemcitabine	gemcitabine	NOUN
fnp-3528	245	10	in	in	ADP
fnp-3528	245	11	panc-1	panc-1	NOUN
fnp-3528	245	12	and	and	CCONJ
fnp-3528	245	13	cfpac-1	cfpac-1	NUM
fnp-3528	245	14	human	human	ADJ
fnp-3528	245	15	pancreatic	pancreatic	ADJ
fnp-3528	245	16	cancer	cancer	NOUN
fnp-3528	245	17	cells.221	cells.221	NOUN
fnp-3528	245	18	in	in	ADP
fnp-3528	245	19	rat	rat	NOUN
fnp-3528	245	20	liver	liver	NOUN
fnp-3528	245	21	,	,	PUNCT
fnp-3528	245	22	an	an	DET
fnp-3528	245	23	induction	induction	NOUN
fnp-3528	245	24	of	of	ADP
fnp-3528	245	25	abca8	abca8	PROPN
fnp-3528	245	26	was	be	AUX
fnp-3528	245	27	demonstrated	demonstrate	VERB
fnp-3528	245	28	via	via	ADP
fnp-3528	245	29	microarray	microarray	ADJ
fnp-3528	245	30	analysis	analysis	NOUN
fnp-3528	245	31	of	of	ADP
fnp-3528	245	32	cdna	cdna	PROPN
fnp-3528	245	33	when	when	SCONJ
fnp-3528	245	34	the	the	DET
fnp-3528	245	35	rats	rat	NOUN
fnp-3528	245	36	were	be	AUX
fnp-3528	245	37	exposed	expose	VERB
fnp-3528	245	38	to	to	ADP
fnp-3528	245	39	polyethyleneglycol	polyethyleneglycol	NOUN
fnp-3528	245	40	-	-	PUNCT
fnp-3528	245	41	block	block	NOUN
fnp-3528	245	42	-	-	PUNCT
fnp-3528	245	43	polylactide	polylactide	NOUN
fnp-3528	245	44	nanoparticles.433	nanoparticles.433	PROPN
fnp-3528	245	45	abca12	abca12	VERB
fnp-3528	245	46	several	several	ADJ
fnp-3528	245	47	lxr	lxr	NOUN
fnp-3528	245	48	and	and	CCONJ
fnp-3528	245	49	ppar	ppar	NOUN
fnp-3528	245	50	agonists	agonist	NOUN
fnp-3528	245	51	induced	induce	VERB
fnp-3528	245	52	abca12	abca12	NOUN
fnp-3528	245	53	/	/	SYM
fnp-3528	245	54	abca12	abca12	NOUN
fnp-3528	245	55	expression	expression	NOUN
fnp-3528	245	56	,	,	PUNCT
fnp-3528	245	57	such	such	ADJ
fnp-3528	245	58	as	as	ADP
fnp-3528	245	59	22-(r)-hydroxycholesterol	22-(r)-hydroxycholesterol	NUM
fnp-3528	245	60	(	(	PUNCT
fnp-3528	245	61	lxr),434	lxr),434	NOUN
fnp-3528	245	62	to901317	to901317	NOUN
fnp-3528	245	63	(	(	PUNCT
fnp-3528	245	64	lxr),430,434	lxr),430,434	NOUN
fnp-3528	245	65	ciglitazone	ciglitazone	NOUN
fnp-3528	245	66	(	(	PUNCT
fnp-3528	245	67	ppar	ppar	NOUN
fnp-3528	245	68	-	-	PUNCT
fnp-3528	245	69	γ),434	γ),434	NOUN
fnp-3528	245	70	gi	gi	NOUN
fnp-3528	245	71	251929x	251929x	NUM
fnp-3528	245	72	(	(	PUNCT
fnp-3528	245	73	ppar	ppar	NOUN
fnp-3528	245	74	-	-	PUNCT
fnp-3528	245	75	γ),434	γ),434	NOUN
fnp-3528	245	76	troglitazone	troglitazone	NOUN
fnp-3528	245	77	(	(	PUNCT
fnp-3528	245	78	ppar	ppar	NOUN
fnp-3528	245	79	-	-	PUNCT
fnp-3528	245	80	γ),434	γ),434	NOUN
fnp-3528	245	81	ceramide	ceramide	NOUN
fnp-3528	245	82	n	n	CCONJ
fnp-3528	245	83	-	-	PUNCT
fnp-3528	245	84	hexanoyl	hexanoyl	NOUN
fnp-3528	245	85	-	-	PUNCT
fnp-3528	245	86	d	d	NOUN
fnp-3528	245	87	-	-	PUNCT
fnp-3528	245	88	erythro	erythro	NOUN
fnp-3528	245	89	-	-	PUNCT
fnp-3528	245	90	sphingosine	sphingosine	NOUN
fnp-3528	245	91	(	(	PUNCT
fnp-3528	245	92	ppar	ppar	NOUN
fnp-3528	245	93	-	-	PUNCT
fnp-3528	245	94	δ),435	δ),435	ADJ
fnp-3528	245	95	and	and	CCONJ
fnp-3528	245	96	gw610742	gw610742	PROPN
fnp-3528	245	97	(	(	PUNCT
fnp-3528	245	98	ppar	ppar	NOUN
fnp-3528	245	99	-	-	PUNCT
fnp-3528	245	100	δ).434	δ).434	NOUN
fnp-3528	245	101	interestingly	interestingly	ADV
fnp-3528	245	102	,	,	PUNCT
fnp-3528	245	103	inhibition	inhibition	NOUN
fnp-3528	245	104	of	of	ADP
fnp-3528	245	105	certain	certain	ADJ
fnp-3528	245	106	enzymes	enzyme	NOUN
fnp-3528	245	107	to	to	PART
fnp-3528	245	108	prevent	prevent	VERB
fnp-3528	245	109	ceramide	ceramide	NOUN
fnp-3528	245	110	processing	processing	NOUN
fnp-3528	245	111	elevated	elevate	VERB
fnp-3528	245	112	intracellular	intracellular	ADJ
fnp-3528	245	113	ceramide	ceramide	NOUN
fnp-3528	245	114	content	content	NOUN
fnp-3528	245	115	and	and	CCONJ
fnp-3528	245	116	subsequently	subsequently	ADV
fnp-3528	245	117	abca12	abca12	NOUN
fnp-3528	245	118	mrna	mrna	PROPN
fnp-3528	245	119	levels.435	levels.435	PROPN
fnp-3528	245	120	these	these	DET
fnp-3528	245	121	enzymes	enzyme	NOUN
fnp-3528	245	122	include	include	VERB
fnp-3528	245	123	,	,	PUNCT
fnp-3528	245	124	for	for	ADP
fnp-3528	245	125	example	example	NOUN
fnp-3528	245	126	,	,	PUNCT
fnp-3528	245	127	the	the	DET
fnp-3528	245	128	glycosyl	glycosyl	NOUN
fnp-3528	245	129	-	-	PUNCT
fnp-3528	245	130	ceramide	ceramide	NOUN
fnp-3528	245	131	-	-	PUNCT
fnp-3528	245	132	transferase	transferase	NOUN
fnp-3528	245	133	synthase	synthase	NOUN
fnp-3528	245	134	[	[	X
fnp-3528	245	135	d	d	X
fnp-3528	245	136	threo-1	threo-1	ADV
fnp-3528	245	137	-	-	PUNCT
fnp-3528	245	138	phenyl-2	phenyl-2	NUM
fnp-3528	245	139	-	-	PUNCT
fnp-3528	245	140	hexadecanoylamino-3	hexadecanoylamino-3	NOUN
fnp-3528	245	141	-	-	PUNCT
fnp-3528	245	142	morpholino-1	morpholino-1	NOUN
fnp-3528	245	143	-	-	PUNCT
fnp-3528	245	144	pro	pro	ADJ
fnp-3528	245	145	-	-	ADJ
fnp-3528	245	146	panol	panol	ADJ
fnp-3528	245	147	(	(	PUNCT
fnp-3528	245	148	d	d	NOUN
fnp-3528	245	149	-	-	NOUN
fnp-3528	245	150	ppmp	ppmp	NOUN
fnp-3528	245	151	)	)	PUNCT
fnp-3528	245	152	,	,	PUNCT
fnp-3528	245	153	d	d	X
fnp-3528	245	154	-	-	PUNCT
fnp-3528	245	155	threo-1	threo-1	NUM
fnp-3528	245	156	-	-	PUNCT
fnp-3528	245	157	phenyl-2	phenyl-2	NUM
fnp-3528	245	158	-	-	PUNCT
fnp-3528	245	159	palmitoyl-3	palmitoyl-3	NOUN
fnp-3528	245	160	-	-	PUNCT
fnp-3528	245	161	pyrrolidinopropanol	pyrrolidinopropanol	NOUN
fnp-3528	245	162	(	(	PUNCT
fnp-3528	245	163	d	d	NOUN
fnp-3528	245	164	-	-	PUNCT
fnp-3528	245	165	pppp	pppp	NOUN
fnp-3528	245	166	/	/	PUNCT
fnp-3528	245	167	p4	p4	NOUN
fnp-3528	245	168	)	)	PUNCT
fnp-3528	245	169	and	and	CCONJ
fnp-3528	245	170	dl	dl	PROPN
fnp-3528	245	171	-	-	PUNCT
fnp-3528	245	172	threo-1	threo-1	NUM
fnp-3528	245	173	-	-	PUNCT
fnp-3528	245	174	phenyl-2	phenyl-2	NUM
fnp-3528	245	175	-	-	PUNCT
fnp-3528	245	176	de	de	NOUN
fnp-3528	245	177	-	-	ADJ
fnp-3528	245	178	canoylamino-3	canoylamino-3	ADJ
fnp-3528	245	179	-	-	PUNCT
fnp-3528	245	180	morpholino-1	morpholino-1	NOUN
fnp-3528	245	181	-	-	PUNCT
fnp-3528	245	182	propanol	propanol	NOUN
fnp-3528	245	183	(	(	PUNCT
fnp-3528	245	184	d	d	NOUN
fnp-3528	245	185	-	-	PUNCT
fnp-3528	245	186	ddmp	ddmp	NOUN
fnp-3528	245	187	)	)	PUNCT
fnp-3528	245	188	]	]	PUNCT
fnp-3528	245	189	,	,	PUNCT
fnp-3528	245	190	the	the	DET
fnp-3528	245	191	sphingomyelin	sphingomyelin	NOUN
fnp-3528	245	192	synthase	synthase	NOUN
fnp-3528	245	193	[	[	X
fnp-3528	245	194	tricyclo[5.2.1.02,6]decanyl)ethanedithioic	tricyclo[5.2.1.02,6]decanyl)ethanedithioic	ADJ
fnp-3528	245	195	acid	acid	NOUN
fnp-3528	245	196	(	(	PUNCT
fnp-3528	245	197	d609	d609	PROPN
fnp-3528	245	198	xanthate	xanthate	PROPN
fnp-3528	245	199	)	)	PUNCT
fnp-3528	245	200	]	]	PUNCT
fnp-3528	245	201	,	,	PUNCT
fnp-3528	245	202	as	as	ADV
fnp-3528	245	203	well	well	ADV
fnp-3528	245	204	as	as	ADP
fnp-3528	245	205	the	the	DET
fnp-3528	245	206	ceramidase	ceramidase	NOUN
fnp-3528	246	1	[	[	X
fnp-3528	246	2	d	d	X
fnp-3528	246	3	-	-	PUNCT
fnp-3528	246	4	erythro-2	erythro-2	NUM
fnp-3528	246	5	-	-	PUNCT
fnp-3528	246	6	tetradecanoylamino-1	tetradecanoylamino-1	NUM
fnp-3528	246	7	-	-	PUNCT
fnp-3528	246	8	phenyl-1	phenyl-1	NOUN
fnp-3528	246	9	-	-	PUNCT
fnp-3528	246	10	propanol	propanol	NOUN
fnp-3528	246	11	(	(	PUNCT
fnp-3528	246	12	d	d	NOUN
fnp-3528	246	13	-	-	PUNCT
fnp-3528	246	14	mapp	mapp	NOUN
fnp-3528	246	15	)	)	PUNCT
fnp-3528	246	16	and	and	CCONJ
fnp-3528	246	17	(	(	PUNCT
fnp-3528	246	18	d	d	NOUN
fnp-3528	246	19	nmappd	nmappd	NOUN
fnp-3528	246	20	/	/	SYM
fnp-3528	246	21	b13)].435	b13)].435	NUM
fnp-3528	246	22	downregulators	downregulator	NOUN
fnp-3528	246	23	abca1	abca1	NOUN
fnp-3528	246	24	lxr	lxr	PROPN
fnp-3528	246	25	and	and	CCONJ
fnp-3528	246	26	rxr	rxr	PROPN
fnp-3528	246	27	pathways	pathway	NOUN
fnp-3528	246	28	–	–	PUNCT
fnp-3528	246	29	intrinsic	intrinsic	ADJ
fnp-3528	246	30	substrates	substrate	NOUN
fnp-3528	246	31	the	the	DET
fnp-3528	246	32	intrinsic	intrinsic	ADJ
fnp-3528	246	33	metabolite	metabolite	NOUN
fnp-3528	246	34	asymmetric	asymmetric	ADJ
fnp-3528	246	35	dimethylarginine	dimethylarginine	ADJ
fnp-3528	246	36	(	(	PUNCT
fnp-3528	246	37	adma	adma	NOUN
fnp-3528	246	38	)	)	PUNCT
fnp-3528	246	39	reduced	reduce	VERB
fnp-3528	246	40	abca1	abca1	PROPN
fnp-3528	246	41	mrna	mrna	PROPN
fnp-3528	246	42	and	and	CCONJ
fnp-3528	246	43	abca1	abca1	NOUN
fnp-3528	246	44	protein	protein	NOUN
fnp-3528	246	45	levels	level	NOUN
fnp-3528	246	46	in	in	ADP
fnp-3528	246	47	human	human	ADJ
fnp-3528	246	48	and	and	CCONJ
fnp-3528	246	49	murine	murine	ADJ
fnp-3528	246	50	j744	j744	PROPN
fnp-3528	246	51	macrophages	macrophage	NOUN
fnp-3528	246	52	in	in	ADP
fnp-3528	246	53	combination	combination	NOUN
fnp-3528	246	54	with	with	ADP
fnp-3528	246	55	oxldl	oxldl	NOUN
fnp-3528	246	56	,	,	PUNCT
fnp-3528	246	57	resulting	result	VERB
fnp-3528	246	58	in	in	ADP
fnp-3528	246	59	increased	increase	VERB
fnp-3528	246	60	intracellular	intracellular	ADJ
fnp-3528	246	61	cholesterol	cholesterol	NOUN
fnp-3528	246	62	and	and	CCONJ
fnp-3528	246	63	triglyceride	triglyceride	INTJ
fnp-3528	246	64	levels.392	levels.392	PROPN
fnp-3528	246	65	this	this	PRON
fnp-3528	246	66	was	be	AUX
fnp-3528	246	67	accompanied	accompany	VERB
fnp-3528	246	68	by	by	ADP
fnp-3528	246	69	decreased	decrease	VERB
fnp-3528	246	70	efflux	efflux	NOUN
fnp-3528	246	71	of	of	ADP
fnp-3528	246	72	cholesterol	cholesterol	NOUN
fnp-3528	246	73	from	from	ADP
fnp-3528	246	74	these	these	DET
fnp-3528	246	75	cells	cell	NOUN
fnp-3528	246	76	.	.	PUNCT
fnp-3528	247	1	the	the	DET
fnp-3528	247	2	authors	author	NOUN
fnp-3528	247	3	suggested	suggest	VERB
fnp-3528	247	4	a	a	DET
fnp-3528	247	5	negative	negative	ADJ
fnp-3528	247	6	effect	effect	NOUN
fnp-3528	247	7	on	on	ADP
fnp-3528	247	8	the	the	DET
fnp-3528	247	9	lxr	lxr	NOUN
fnp-3528	247	10	-	-	PUNCT
fnp-3528	247	11	α	α	NOUN
fnp-3528	247	12	pathway	pathway	NOUN
fnp-3528	247	13	.	.	PUNCT
fnp-3528	248	1	in	in	ADP
fnp-3528	248	2	this	this	DET
fnp-3528	248	3	regard	regard	NOUN
fnp-3528	248	4	,	,	PUNCT
fnp-3528	248	5	the	the	DET
fnp-3528	248	6	lxr	lxr	PROPN
fnp-3528	248	7	-	-	PUNCT
fnp-3528	248	8	α	α	PROPN
fnp-3528	248	9	downregulator	downregulator	PROPN
fnp-3528	248	10	homocysteine	homocysteine	PROPN
fnp-3528	248	11	significantly	significantly	ADV
fnp-3528	248	12	reduced	reduce	VERB
fnp-3528	248	13	abca1	abca1	NOUN
fnp-3528	248	14	/	/	SYM
fnp-3528	248	15	abca1	abca1	NOUN
fnp-3528	248	16	mrna	mrna	NOUN
fnp-3528	248	17	and	and	CCONJ
fnp-3528	248	18	abca1	abca1	NOUN
fnp-3528	248	19	protein	protein	NOUN
fnp-3528	248	20	expression	expression	NOUN
fnp-3528	248	21	in	in	ADP
fnp-3528	248	22	vitro	vitro	X
fnp-3528	248	23	in	in	ADP
fnp-3528	248	24	thp-1	thp-1	SYM
fnp-3528	248	25	macrophages	macrophage	NOUN
fnp-3528	248	26	as	as	ADV
fnp-3528	248	27	well	well	ADV
fnp-3528	248	28	as	as	ADP
fnp-3528	248	29	in	in	ADP
fnp-3528	248	30	vivo	vivo	NOUN
fnp-3528	248	31	in	in	ADP
fnp-3528	248	32	macrophages	macrophage	NOUN
fnp-3528	248	33	from	from	ADP
fnp-3528	248	34	apoe	apoe	ADJ
fnp-3528	248	35	knock	knock	NOUN
fnp-3528	248	36	-	-	PUNCT
fnp-3528	248	37	out	out	ADP
fnp-3528	248	38	c57bl/6	c57bl/6	NOUN
fnp-3528	248	39	mice.335	mice.335	VERB
fnp-3528	248	40	the	the	DET
fnp-3528	248	41	cattle	cattle	NOUN
fnp-3528	248	42	metabolite	metabolite	NOUN
fnp-3528	248	43	dipeptide	dipeptide	ADJ
fnp-3528	248	44	phenylalanine	phenylalanine	NOUN
fnp-3528	248	45	-	-	PUNCT
fnp-3528	248	46	proline	proline	NOUN
fnp-3528	248	47	decreased	decrease	VERB
fnp-3528	248	48	abca1	abca1	NOUN
fnp-3528	248	49	mrna	mrna	PROPN
fnp-3528	248	50	and	and	CCONJ
fnp-3528	248	51	abca1	abca1	NOUN
fnp-3528	248	52	protein	protein	NOUN
fnp-3528	248	53	levels	level	NOUN
fnp-3528	248	54	in	in	ADP
fnp-3528	248	55	human	human	ADJ
fnp-3528	248	56	colorectal	colorectal	ADJ
fnp-3528	248	57	adenocarcinoma	adenocarcinoma	NOUN
fnp-3528	248	58	-	-	PUNCT
fnp-3528	248	59	derived	derive	VERB
fnp-3528	248	60	caco-2	caco-2	NUM
fnp-3528	248	61	cells.436	cells.436	VERB
fnp-3528	248	62	the	the	DET
fnp-3528	248	63	observed	observed	ADJ
fnp-3528	248	64	downregulation	downregulation	NOUN
fnp-3528	248	65	of	of	ADP
fnp-3528	248	66	lxrb	lxrb	PROPN
fnp-3528	248	67	mrna	mrna	PROPN
fnp-3528	248	68	could	could	AUX
fnp-3528	248	69	explain	explain	VERB
fnp-3528	248	70	the	the	DET
fnp-3528	248	71	negative	negative	ADJ
fnp-3528	248	72	impact	impact	NOUN
fnp-3528	248	73	on	on	ADP
fnp-3528	248	74	abca1	abca1	NOUN
fnp-3528	248	75	expression	expression	NOUN
fnp-3528	248	76	.	.	PUNCT
fnp-3528	249	1	in	in	ADP
fnp-3528	249	2	vivo	vivo	NOUN
fnp-3528	249	3	,	,	PUNCT
fnp-3528	249	4	the	the	DET
fnp-3528	249	5	jejunal	jejunal	ADJ
fnp-3528	249	6	abca1	abca1	PROPN
fnp-3528	249	7	mrna	mrna	PROPN
fnp-3528	249	8	levels	level	NOUN
fnp-3528	249	9	were	be	AUX
fnp-3528	249	10	decreased	decrease	VERB
fnp-3528	249	11	in	in	ADP
fnp-3528	249	12	wistar	wistar	PROPN
fnp-3528	249	13	rats.436	rats.436	PROPN
fnp-3528	249	14	the	the	DET
fnp-3528	249	15	abca1	abca1	NOUN
fnp-3528	249	16	substrate	substrate	NOUN
fnp-3528	249	17	α	α	NOUN
fnp-3528	249	18	-	-	PUNCT
fnp-3528	249	19	tocopherol230	tocopherol230	ADJ
fnp-3528	249	20	reduced	reduced	ADJ
fnp-3528	249	21	abca1	abca1	NOUN
fnp-3528	249	22	/	/	SYM
fnp-3528	249	23	abca1	abca1	NOUN
fnp-3528	249	24	mrna	mrna	PROPN
fnp-3528	249	25	levels	level	NOUN
fnp-3528	249	26	in	in	ADP
fnp-3528	249	27	vitro	vitro	X
fnp-3528	249	28	and	and	CCONJ
fnp-3528	249	29	in	in	ADP
fnp-3528	249	30	vivo.231	vivo.231	ADJ
fnp-3528	249	31	the	the	DET
fnp-3528	249	32	same	same	ADJ
fnp-3528	249	33	effects	effect	NOUN
fnp-3528	249	34	were	be	AUX
fnp-3528	249	35	observed	observe	VERB
fnp-3528	249	36	for	for	ADP
fnp-3528	249	37	γ	γ	NOUN
fnp-3528	249	38	-	-	NOUN
fnp-3528	249	39	tocopherol	tocopherol	NOUN
fnp-3528	249	40	in	in	ADP
fnp-3528	249	41	vitro	vitro	X
fnp-3528	249	42	,	,	PUNCT
fnp-3528	249	43	most	most	ADV
fnp-3528	249	44	likely	likely	ADJ
fnp-3528	249	45	through	through	ADP
fnp-3528	249	46	the	the	DET
fnp-3528	249	47	same	same	ADJ
fnp-3528	249	48	mechanism	mechanism	NOUN
fnp-3528	249	49	.	.	PUNCT
fnp-3528	250	1	the	the	DET
fnp-3528	250	2	authors	author	NOUN
fnp-3528	250	3	suggested	suggest	VERB
fnp-3528	250	4	a	a	DET
fnp-3528	250	5	negative	negative	ADJ
fnp-3528	250	6	impact	impact	NOUN
fnp-3528	250	7	on	on	ADP
fnp-3528	250	8	the	the	DET
fnp-3528	250	9	lxr	lxr	ADJ
fnp-3528	250	10	pathway	pathway	NOUN
fnp-3528	250	11	due	due	ADP
fnp-3528	250	12	to	to	ADP
fnp-3528	250	13	deprived	deprive	VERB
fnp-3528	250	14	oxycholesterol	oxycholesterol	NOUN
fnp-3528	250	15	derivatives	derivative	NOUN
fnp-3528	250	16	after	after	SCONJ
fnp-3528	250	17	α	α	NOUN
fnp-3528	250	18	-	-	ADJ
fnp-3528	250	19	tocopherol	tocopherol	NOUN
fnp-3528	250	20	treatment	treatment	NOUN
fnp-3528	250	21	both	both	CCONJ
fnp-3528	250	22	in	in	ADP
fnp-3528	250	23	vitro	vitro	X
fnp-3528	250	24	in	in	ADP
fnp-3528	250	25	hep3b	hep3b	PROPN
fnp-3528	250	26	cells	cell	NOUN
fnp-3528	250	27	and	and	CCONJ
fnp-3528	250	28	in	in	ADP
fnp-3528	250	29	vivo	vivo	NOUN
fnp-3528	250	30	in	in	ADP
fnp-3528	250	31	rat	rat	NOUN
fnp-3528	250	32	liver.231	liver.231	ADJ
fnp-3528	250	33	lxr	lxr	NOUN
fnp-3528	250	34	and	and	CCONJ
fnp-3528	250	35	rxr	rxr	PROPN
fnp-3528	250	36	pathways	pathways	PROPN
fnp-3528	250	37	sterane	sterane	NOUN
fnp-3528	250	38	and	and	CCONJ
fnp-3528	250	39	sterane	sterane	NOUN
fnp-3528	250	40	-	-	PUNCT
fnp-3528	250	41	like	like	ADJ
fnp-3528	250	42	natural	natural	ADJ
fnp-3528	250	43	compounds	compound	NOUN
fnp-3528	250	44	cholesterol	cholesterol	NOUN
fnp-3528	250	45	and	and	CCONJ
fnp-3528	250	46	its	its	PRON
fnp-3528	250	47	derivatives	derivative	NOUN
fnp-3528	250	48	have	have	AUX
fnp-3528	250	49	extensively	extensively	ADV
fnp-3528	250	50	been	be	AUX
fnp-3528	250	51	used	use	VERB
fnp-3528	250	52	to	to	PART
fnp-3528	250	53	induce	induce	VERB
fnp-3528	250	54	abca1	abca1	NOUN
fnp-3528	250	55	/	/	SYM
fnp-3528	250	56	abca1	abca1	NOUN
fnp-3528	250	57	expression122,205,249,252,259,262	expression122,205,249,252,259,262	PROPN
fnp-3528	250	58	-	-	PUNCT
fnp-3528	250	59	264,268,277,278,305	264,268,277,278,305	NUM
fnp-3528	250	60	-	-	PUNCT
fnp-3528	250	61	315,319	315,319	NUM
fnp-3528	250	62	-	-	SYM
fnp-3528	250	63	328	328	NUM
fnp-3528	250	64	however	however	ADV
fnp-3528	250	65	,	,	PUNCT
fnp-3528	250	66	mid	mid	ADJ
fnp-3528	250	67	-	-	ADJ
fnp-3528	250	68	term	term	NOUN
fnp-3528	250	69	exposure	exposure	NOUN
fnp-3528	250	70	to	to	ADP
fnp-3528	250	71	excess	excess	ADJ
fnp-3528	250	72	cholesterol	cholesterol	NOUN
fnp-3528	250	73	decreased	decrease	VERB
fnp-3528	250	74	abca1	abca1	NOUN
fnp-3528	250	75	expression	expression	NOUN
fnp-3528	250	76	though	though	SCONJ
fnp-3528	250	77	a	a	DET
fnp-3528	250	78	negative	negative	ADJ
fnp-3528	250	79	impact	impact	NOUN
fnp-3528	250	80	on	on	ADP
fnp-3528	250	81	lxra	lxra	NOUN
fnp-3528	250	82	,	,	PUNCT
fnp-3528	250	83	lxrb	lxrb	NOUN
fnp-3528	250	84	,	,	PUNCT
fnp-3528	250	85	and	and	CCONJ
fnp-3528	250	86	pparg	pparg	NOUN
fnp-3528	250	87	expression.321	expression.321	PROPN
fnp-3528	250	88	similar	similar	ADJ
fnp-3528	250	89	observations	observation	NOUN
fnp-3528	250	90	have	have	AUX
fnp-3528	250	91	been	be	AUX
fnp-3528	250	92	made	make	VERB
fnp-3528	250	93	for	for	ADP
fnp-3528	250	94	the	the	DET
fnp-3528	250	95	sterol	sterol	NOUN
fnp-3528	250	96	derivative	derivative	ADJ
fnp-3528	250	97	dexamethasone	dexamethasone	NOUN
fnp-3528	250	98	,	,	PUNCT
fnp-3528	250	99	which	which	PRON
fnp-3528	250	100	also	also	ADV
fnp-3528	250	101	reduced	reduce	VERB
fnp-3528	250	102	abca1	abca1	NOUN
fnp-3528	250	103	/	/	SYM
fnp-3528	250	104	abca1	abca1	NOUN
fnp-3528	250	105	mrna	mrna	NOUN
fnp-3528	250	106	and	and	CCONJ
fnp-3528	250	107	abca1	abca1	NOUN
fnp-3528	250	108	protein	protein	NOUN
fnp-3528	250	109	expression	expression	NOUN
fnp-3528	250	110	in	in	ADP
fnp-3528	250	111	vitro	vitro	X
fnp-3528	250	112	and	and	CCONJ
fnp-3528	250	113	in	in	ADP
fnp-3528	250	114	vivo	vivo	NOUN
fnp-3528	250	115	by	by	ADP
fnp-3528	250	116	downregulation	downregulation	NOUN
fnp-3528	250	117	of	of	ADP
fnp-3528	250	118	lxra	lxra	NOUN
fnp-3528	250	119	/	/	SYM
fnp-3528	250	120	lxra	lxra	NOUN
fnp-3528	250	121	mrna	mrna	NOUN
fnp-3528	250	122	and	and	CCONJ
fnp-3528	250	123	lxr	lxr	PROPN
fnp-3528	250	124	-	-	PUNCT
fnp-3528	250	125	α	α	NOUN
fnp-3528	250	126	protein	protein	NOUN
fnp-3528	250	127	levels	level	NOUN
fnp-3528	250	128	as	as	ADV
fnp-3528	250	129	well	well	ADV
fnp-3528	250	130	as	as	ADP
fnp-3528	250	131	upregulation	upregulation	NOUN
fnp-3528	250	132	of	of	ADP
fnp-3528	250	133	srebp2	srebp2	NOUN
fnp-3528	250	134	and	and	CCONJ
fnp-3528	250	135	hmg	hmg	NOUN
fnp-3528	250	136	-	-	PUNCT
fnp-3528	250	137	coa	coa	NOUN
fnp-3528	250	138	-	-	PUNCT
fnp-3528	250	139	reductase	reductase	NOUN
fnp-3528	250	140	gene	gene	NOUN
fnp-3528	250	141	expression	expression	NOUN
fnp-3528	250	142	(	(	PUNCT
fnp-3528	250	143	hmgcr).437	hmgcr).437	PROPN
fnp-3528	250	144	finally	finally	ADV
fnp-3528	250	145	,	,	PUNCT
fnp-3528	250	146	an	an	DET
fnp-3528	250	147	abca1	abca1	NOUN
fnp-3528	250	148	mrna	mrna	NOUN
fnp-3528	250	149	reduction	reduction	NOUN
fnp-3528	250	150	was	be	AUX
fnp-3528	250	151	observed	observe	VERB
fnp-3528	250	152	in	in	ADP
fnp-3528	250	153	murine	murine	ADJ
fnp-3528	250	154	raw264.7	raw264.7	ADJ
fnp-3528	250	155	macrophages	macrophage	NOUN
fnp-3528	250	156	for	for	SCONJ
fnp-3528	250	157	the	the	DET
fnp-3528	250	158	thelenota	thelenota	NOUN
fnp-3528	250	159	ananas	ananas	NOUN
fnp-3528	250	160	-	-	PUNCT
fnp-3528	250	161	derived	derive	VERB
fnp-3528	250	162	saponin	saponin	NOUN
fnp-3528	250	163	desulfated	desulfate	VERB
fnp-3528	250	164	holothurin	holothurin	PROPN
fnp-3528	250	165	a.438	a.438	PROPN
fnp-3528	250	166	interestingly	interestingly	ADV
fnp-3528	250	167	,	,	PUNCT
fnp-3528	250	168	hmgcr	hmgcr	PROPN
fnp-3528	250	169	was	be	AUX
fnp-3528	250	170	downregulated	downregulate	VERB
fnp-3528	250	171	after	after	ADP
fnp-3528	250	172	exposure	exposure	NOUN
fnp-3528	250	173	to	to	ADP
fnp-3528	250	174	desulfated	desulfated	ADJ
fnp-3528	250	175	holothurin	holothurin	PROPN
fnp-3528	250	176	a	a	NOUN
fnp-3528	250	177	,	,	PUNCT
fnp-3528	250	178	which	which	PRON
fnp-3528	250	179	contradicts	contradict	VERB
fnp-3528	250	180	other	other	ADJ
fnp-3528	250	181	findings.437	findings.437	NOUN
fnp-3528	250	182	lxr	lxr	NOUN
fnp-3528	250	183	and	and	CCONJ
fnp-3528	250	184	rxr	rxr	PROPN
fnp-3528	250	185	pathways	pathway	NOUN
fnp-3528	250	186	–	–	PUNCT
fnp-3528	250	187	other	other	ADJ
fnp-3528	250	188	natural	natural	ADJ
fnp-3528	250	189	compounds	compound	NOUN
fnp-3528	250	190	certain	certain	ADJ
fnp-3528	250	191	chalcone	chalcone	NOUN
fnp-3528	250	192	derivatives	derivative	NOUN
fnp-3528	250	193	also	also	ADV
fnp-3528	250	194	caused	cause	VERB
fnp-3528	250	195	reduced	reduced	ADJ
fnp-3528	250	196	expression	expression	NOUN
fnp-3528	250	197	of	of	ADP
fnp-3528	250	198	abca1	abca1	NOUN
fnp-3528	250	199	protein.363	protein.363	ADV
fnp-3528	250	200	in	in	ADP
fnp-3528	250	201	addition	addition	NOUN
fnp-3528	250	202	,	,	PUNCT
fnp-3528	250	203	lipopolysaccharides	lipopolysaccharide	NOUN
fnp-3528	250	204	reduced	reduce	VERB
fnp-3528	250	205	abca1	abca1	NOUN
fnp-3528	250	206	protein	protein	NOUN
fnp-3528	250	207	content	content	NOUN
fnp-3528	250	208	in	in	ADP
fnp-3528	250	209	endometrial	endometrial	ADJ
fnp-3528	250	210	endothelial	endothelial	ADJ
fnp-3528	250	211	cells	cell	NOUN
fnp-3528	250	212	from	from	ADP
fnp-3528	250	213	c57bl/6	c57bl/6	NOUN
fnp-3528	250	214	mice	mouse	NOUN
fnp-3528	250	215	,	,	PUNCT
fnp-3528	250	216	which	which	PRON
fnp-3528	250	217	was	be	AUX
fnp-3528	250	218	accompanied	accompany	VERB
fnp-3528	250	219	by	by	ADP
fnp-3528	250	220	increased	increase	VERB
fnp-3528	250	221	cholesterol	cholesterol	NOUN
fnp-3528	250	222	levels	level	NOUN
fnp-3528	250	223	in	in	ADP
fnp-3528	250	224	these	these	DET
fnp-3528	250	225	cells.374	cells.374	NOUN
fnp-3528	250	226	a	a	DET
fnp-3528	250	227	parallel	parallel	ADJ
fnp-3528	250	228	reduction	reduction	NOUN
fnp-3528	250	229	in	in	ADP
fnp-3528	250	230	lxr	lxr	PROPN
fnp-3528	250	231	-	-	PUNCT
fnp-3528	250	232	α	α	NOUN
fnp-3528	250	233	protein	protein	NOUN
fnp-3528	250	234	was	be	AUX
fnp-3528	250	235	also	also	ADV
fnp-3528	250	236	observed	observe	VERB
fnp-3528	250	237	.	.	PUNCT
fnp-3528	251	1	finally	finally	ADV
fnp-3528	251	2	,	,	PUNCT
fnp-3528	251	3	the	the	DET
fnp-3528	251	4	carcinogenic	carcinogenic	ADJ
fnp-3528	251	5	agent	agent	NOUN
fnp-3528	251	6	n	n	CCONJ
fnp-3528	251	7	-	-	PUNCT
fnp-3528	251	8	nitrosodiethylamine	nitrosodiethylamine	NOUN
fnp-3528	251	9	(	(	PUNCT
fnp-3528	251	10	ndea	ndea	NOUN
fnp-3528	251	11	)	)	PUNCT
fnp-3528	251	12	demonstrated	demonstrate	VERB
fnp-3528	251	13	in	in	ADP
fnp-3528	251	14	vivo	vivo	NOUN
fnp-3528	251	15	in	in	ADP
fnp-3528	251	16	wistar	wistar	PROPN
fnp-3528	251	17	albino	albino	PROPN
fnp-3528	251	18	rats	rat	VERB
fnp-3528	251	19	a	a	DET
fnp-3528	251	20	downregulation	downregulation	NOUN
fnp-3528	251	21	of	of	ADP
fnp-3528	251	22	lxra	lxra	NOUN
fnp-3528	251	23	and	and	CCONJ
fnp-3528	251	24	lxrb	lxrb	PROPN
fnp-3528	251	25	mrna	mrna	PROPN
fnp-3528	251	26	as	as	ADV
fnp-3528	251	27	well	well	ADV
fnp-3528	251	28	as	as	ADP
fnp-3528	251	29	lxr	lxr	PROPN
fnp-3528	251	30	-	-	PUNCT
fnp-3528	251	31	α	α	PROPN
fnp-3528	251	32	and	and	CCONJ
fnp-3528	251	33	lxr	lxr	PROPN
fnp-3528	251	34	-	-	PUNCT
fnp-3528	251	35	β	β	NOUN
fnp-3528	251	36	protein	protein	NOUN
fnp-3528	251	37	levels	level	NOUN
fnp-3528	251	38	and	and	CCONJ
fnp-3528	251	39	,	,	PUNCT
fnp-3528	251	40	subsequently	subsequently	ADV
fnp-3528	251	41	,	,	PUNCT
fnp-3528	252	1	abca1	abca1	PROPN
fnp-3528	252	2	protein.368	protein.368	PROPN
fnp-3528	252	3	lxr	lxr	PROPN
fnp-3528	252	4	and	and	CCONJ
fnp-3528	252	5	rxr	rxr	PROPN
fnp-3528	252	6	pathways	pathway	NOUN
fnp-3528	252	7	–	–	PUNCT
fnp-3528	252	8	synthetic	synthetic	ADJ
fnp-3528	252	9	compounds	compound	NOUN
fnp-3528	252	10	and	and	CCONJ
fnp-3528	252	11	hts	hts	PROPN
fnp-3528	252	12	hits	hit	VERB
fnp-3528	252	13	in	in	ADP
fnp-3528	252	14	terms	term	NOUN
fnp-3528	252	15	of	of	ADP
fnp-3528	252	16	other	other	ADJ
fnp-3528	252	17	lxr	lxr	ADJ
fnp-3528	252	18	antagonists	antagonist	NOUN
fnp-3528	252	19	and	and	CCONJ
fnp-3528	252	20	downregulators	downregulator	NOUN
fnp-3528	252	21	,	,	PUNCT
fnp-3528	252	22	gsk2033	gsk2033	NOUN
fnp-3528	252	23	(	(	PUNCT
fnp-3528	252	24	figure	figure	NOUN
fnp-3528	252	25	 	 	SPACE
fnp-3528	252	26	2),272,330,333	2),272,330,333	NUM
fnp-3528	252	27	5cppss-50,357	5cppss-50,357	NUM
fnp-3528	252	28	and	and	CCONJ
fnp-3528	252	29	sr9243333	sr9243333	NOUN
fnp-3528	252	30	reduced	reduce	VERB
fnp-3528	252	31	abca1	abca1	PROPN
fnp-3528	252	32	mrna	mrna	PROPN
fnp-3528	252	33	and	and	CCONJ
fnp-3528	252	34	abca1	abca1	NOUN
fnp-3528	252	35	protein	protein	NOUN
fnp-3528	253	1	expression.272,330,333,357	expression.272,330,333,357	CCONJ
fnp-3528	253	2	hmg	hmg	NOUN
fnp-3528	253	3	-	-	PUNCT
fnp-3528	253	4	coa	coa	NOUN
fnp-3528	253	5	-	-	PUNCT
fnp-3528	253	6	reductase	reductase	NOUN
fnp-3528	253	7	pathways	pathway	NOUN
fnp-3528	253	8	–	–	PUNCT
fnp-3528	253	9	intrinsic	intrinsic	ADJ
fnp-3528	253	10	substrates	substrate	NOUN
fnp-3528	253	11	and	and	CCONJ
fnp-3528	253	12	pharmacological	pharmacological	ADJ
fnp-3528	253	13	drugs	drug	NOUN
fnp-3528	253	14	the	the	DET
fnp-3528	253	15	peptide	peptide	ADJ
fnp-3528	253	16	hormone	hormone	NOUN
fnp-3528	253	17	angiotensin	angiotensin	PROPN
fnp-3528	253	18	ii	ii	PROPN
fnp-3528	253	19	reduced	reduce	VERB
fnp-3528	253	20	cholesterol	cholesterol	NOUN
fnp-3528	253	21	efflux	efflux	NOUN
fnp-3528	253	22	from	from	ADP
fnp-3528	253	23	murine	murine	ADJ
fnp-3528	253	24	peritoneal	peritoneal	ADJ
fnp-3528	253	25	macrophages.439	macrophages.439	NOUN
fnp-3528	253	26	this	this	DET
fnp-3528	253	27	reduction	reduction	NOUN
fnp-3528	253	28	could	could	AUX
fnp-3528	253	29	be	be	AUX
fnp-3528	253	30	reversed	reverse	VERB
fnp-3528	253	31	by	by	ADP
fnp-3528	253	32	the	the	DET
fnp-3528	253	33	angiotensin	angiotensin	PROPN
fnp-3528	253	34	ii	ii	PROPN
fnp-3528	253	35	receptor	receptor	NOUN
fnp-3528	253	36	antagonist	antagonist	NOUN
fnp-3528	253	37	losartan	losartan	ADJ
fnp-3528	253	38	.	.	PUNCT
fnp-3528	254	1	the	the	DET
fnp-3528	254	2	authors	author	NOUN
fnp-3528	254	3	concluded	conclude	VERB
fnp-3528	254	4	that	that	SCONJ
fnp-3528	254	5	abca1	abca1	NOUN
fnp-3528	254	6	was	be	AUX
fnp-3528	254	7	not	not	PART
fnp-3528	254	8	involved	involve	VERB
fnp-3528	254	9	in	in	ADP
fnp-3528	254	10	this	this	DET
fnp-3528	254	11	process	process	NOUN
fnp-3528	254	12	,	,	PUNCT
fnp-3528	254	13	as	as	SCONJ
fnp-3528	254	14	no	no	DET
fnp-3528	254	15	concurrent	concurrent	ADJ
fnp-3528	254	16	change	change	NOUN
fnp-3528	254	17	in	in	ADP
fnp-3528	254	18	abca1	abca1	NOUN
fnp-3528	254	19	expression	expression	NOUN
fnp-3528	254	20	was	be	AUX
fnp-3528	254	21	observed.439	observed.439	PROPN
fnp-3528	254	22	however	however	ADV
fnp-3528	254	23	,	,	PUNCT
fnp-3528	254	24	in	in	ADP
fnp-3528	254	25	another	another	DET
fnp-3528	254	26	report	report	NOUN
fnp-3528	254	27	,	,	PUNCT
fnp-3528	254	28	angiotensin	angiotensin	PROPN
fnp-3528	254	29	ii	ii	PROPN
fnp-3528	254	30	indeed	indeed	ADV
fnp-3528	254	31	demonstrated	demonstrate	VERB
fnp-3528	254	32	a	a	DET
fnp-3528	254	33	reduction	reduction	NOUN
fnp-3528	254	34	of	of	ADP
fnp-3528	254	35	abca1	abca1	PROPN
fnp-3528	254	36	mrna	mrna	PROPN
fnp-3528	254	37	and	and	CCONJ
fnp-3528	254	38	abca1	abca1	NOUN
fnp-3528	254	39	protein	protein	NOUN
fnp-3528	254	40	levels	level	NOUN
fnp-3528	254	41	in	in	ADP
fnp-3528	254	42	human	human	ADJ
fnp-3528	254	43	podocytes.440	podocytes.440	PROPN
fnp-3528	254	44	the	the	DET
fnp-3528	254	45	authors	author	NOUN
fnp-3528	254	46	concluded	conclude	VERB
fnp-3528	254	47	a	a	DET
fnp-3528	254	48	contribution	contribution	NOUN
fnp-3528	254	49	of	of	ADP
fnp-3528	254	50	the	the	DET
fnp-3528	254	51	hmg	hmg	NOUN
fnp-3528	254	52	-	-	PUNCT
fnp-3528	254	53	coa	coa	NOUN
fnp-3528	254	54	-	-	PUNCT
fnp-3528	254	55	reductase	reductase	NOUN
fnp-3528	254	56	,	,	PUNCT
fnp-3528	254	57	srebp1	srebp1	NOUN
fnp-3528	254	58	,	,	PUNCT
fnp-3528	254	59	and	and	CCONJ
fnp-3528	254	60	srebp2.440	srebp2.440	PROPN
fnp-3528	254	61	geranylgeraniol	geranylgeraniol	PROPN
fnp-3528	254	62	pyrophosphate	pyrophosphate	NOUN
fnp-3528	254	63	(	(	PUNCT
fnp-3528	254	64	ggpp	ggpp	NOUN
fnp-3528	254	65	;	;	PUNCT
fnp-3528	254	66	figure	figure	NOUN
fnp-3528	254	67	 	 	SPACE
fnp-3528	254	68	2	2	NUM
fnp-3528	254	69	)	)	PUNCT
fnp-3528	254	70	,	,	PUNCT
fnp-3528	254	71	a	a	DET
fnp-3528	254	72	product	product	NOUN
fnp-3528	254	73	of	of	ADP
fnp-3528	254	74	the	the	DET
fnp-3528	254	75	mevalonate	mevalonate	ADJ
fnp-3528	254	76	pathway	pathway	NOUN
fnp-3528	254	77	,	,	PUNCT
fnp-3528	254	78	reduced	reduce	VERB
fnp-3528	254	79	abca1	abca1	NOUN
fnp-3528	254	80	mrna	mrna	PROPN
fnp-3528	254	81	expression	expression	NOUN
fnp-3528	254	82	in	in	ADP
fnp-3528	254	83	human	human	ADJ
fnp-3528	254	84	macrophages	macrophage	NOUN
fnp-3528	254	85	,	,	PUNCT
fnp-3528	254	86	which	which	PRON
fnp-3528	254	87	was	be	AUX
fnp-3528	254	88	blocked	block	VERB
fnp-3528	254	89	by	by	ADP
fnp-3528	254	90	the	the	DET
fnp-3528	254	91	prenylation	prenylation	NOUN
fnp-3528	254	92	inhibitors	inhibitor	NOUN
fnp-3528	254	93	l836,978	l836,978	ADP
fnp-3528	254	94	and	and	CCONJ
fnp-3528	254	95	l-839,867.314	l-839,867.314	VERB
fnp-3528	254	96	in	in	ADP
fnp-3528	254	97	addition	addition	NOUN
fnp-3528	254	98	,	,	PUNCT
fnp-3528	254	99	a	a	DET
fnp-3528	254	100	reduction	reduction	NOUN
fnp-3528	254	101	of	of	ADP
fnp-3528	254	102	abca1	abca1	NOUN
fnp-3528	254	103	-	-	PUNCT
fnp-3528	254	104	mediated	mediate	VERB
fnp-3528	254	105	cholesterol	cholesterol	NOUN
fnp-3528	254	106	export	export	NOUN
fnp-3528	254	107	was	be	AUX
fnp-3528	254	108	observed	observe	VERB
fnp-3528	254	109	,	,	PUNCT
fnp-3528	254	110	which	which	PRON
fnp-3528	254	111	is	be	AUX
fnp-3528	254	112	also	also	ADV
fnp-3528	254	113	true	true	ADJ
fnp-3528	254	114	for	for	ADP
fnp-3528	254	115	mevalonate	mevalonate	ADJ
fnp-3528	254	116	itself.318	itself.318	PRON
fnp-3528	254	117	ggpp	ggpp	PROPN
fnp-3528	254	118	was	be	AUX
fnp-3528	254	119	used	use	VERB
fnp-3528	254	120	as	as	ADP
fnp-3528	254	121	a	a	DET
fnp-3528	254	122	standard	standard	ADJ
fnp-3528	254	123	abca1	abca1	NOUN
fnp-3528	254	124	downregulator	downregulator	NOUN
fnp-3528	254	125	in	in	ADP
fnp-3528	254	126	certain	certain	ADJ
fnp-3528	254	127	studies.279,354,366	studies.279,354,366	PROPN
fnp-3528	254	128	as	as	SCONJ
fnp-3528	254	129	discussed	discuss	VERB
fnp-3528	254	130	above	above	ADV
fnp-3528	254	131	,	,	PUNCT
fnp-3528	254	132	atorvastatin,343	atorvastatin,343	PROPN
fnp-3528	254	133	fluvastatin,312	fluvastatin,312	PROPN
fnp-3528	254	134	pitavastatin,318,343	pitavastatin,318,343	NOUN
fnp-3528	254	135	and	and	CCONJ
fnp-3528	254	136	simvasta	simvasta	NOUN
fnp-3528	254	137	-	-	PUNCT
fnp-3528	254	138	tin312,343	tin312,343	NOUN
fnp-3528	254	139	have	have	AUX
fnp-3528	254	140	been	be	AUX
fnp-3528	254	141	shown	show	VERB
fnp-3528	254	142	to	to	PART
fnp-3528	254	143	increase	increase	VERB
fnp-3528	254	144	abca1	abca1	NOUN
fnp-3528	254	145	/	/	SYM
fnp-3528	254	146	abca1	abca1	PROPN
fnp-3528	254	147	mrna	mrna	PROPN
fnp-3528	254	148	levels,312,343	levels,312,343	NOUN
fnp-3528	254	149	and	and	CCONJ
fnp-3528	254	150	to	to	PART
fnp-3528	254	151	enhance	enhance	VERB
fnp-3528	254	152	abca1	abca1	NOUN
fnp-3528	254	153	-	-	PUNCT
fnp-3528	254	154	mediated	mediate	VERB
fnp-3528	254	155	cholesterol	cholesterol	NOUN
fnp-3528	254	156	efflux.318	efflux.318	NOUN
fnp-3528	254	157	however	however	ADV
fnp-3528	254	158	,	,	PUNCT
fnp-3528	254	159	atorvastatin,312,321,384	atorvastatin,312,321,384	ADJ
fnp-3528	254	160	fluvastatin,312	fluvastatin,312	PROPN
fnp-3528	254	161	pitavastatin432	pitavastatin432	PROPN
fnp-3528	254	162	and	and	CCONJ
fnp-3528	254	163	simvastatin312,384	simvastatin312,384	NUM
fnp-3528	254	164	have	have	AUX
fnp-3528	254	165	also	also	ADV
fnp-3528	254	166	been	be	AUX
fnp-3528	254	167	reported	report	VERB
fnp-3528	254	168	to	to	PART
fnp-3528	254	169	reduce	reduce	VERB
fnp-3528	254	170	abca1	abca1	NOUN
fnp-3528	254	171	/	/	SYM
fnp-3528	254	172	abca1	abca1	NOUN
fnp-3528	254	173	transcription312,321,384,432	transcription312,321,384,432	NOUN
fnp-3528	254	174	and	and	CCONJ
fnp-3528	254	175	abca1	abca1	NOUN
fnp-3528	254	176	-	-	PUNCT
fnp-3528	254	177	mediated	mediate	VERB
fnp-3528	254	178	cholesterol	cholesterol	NOUN
fnp-3528	254	179	efflux.384,431	efflux.384,431	NOUN
fnp-3528	254	180	these	these	DET
fnp-3528	254	181	observations	observation	NOUN
fnp-3528	254	182	are	be	AUX
fnp-3528	254	183	in	in	ADP
fnp-3528	254	184	agreement	agreement	NOUN
fnp-3528	254	185	with	with	ADP
fnp-3528	254	186	other	other	ADJ
fnp-3528	254	187	reports	report	NOUN
fnp-3528	254	188	on	on	ADP
fnp-3528	254	189	hmg	hmg	NOUN
fnp-3528	254	190	-	-	PUNCT
fnp-3528	254	191	coa	coa	NOUN
fnp-3528	254	192	-	-	PUNCT
fnp-3528	254	193	reductase	reductase	NOUN
fnp-3528	254	194	inhibitors	inhibitor	NOUN
fnp-3528	254	195	that	that	PRON
fnp-3528	254	196	downregulated	downregulate	VERB
fnp-3528	254	197	abca1.312,431	abca1.312,431	PRON
fnp-3528	254	198	in	in	ADP
fnp-3528	254	199	particular	particular	ADJ
fnp-3528	254	200	,	,	PUNCT
fnp-3528	254	201	lovastatin,312	lovastatin,312	PROPN
fnp-3528	254	202	mevastatin	mevastatin	NOUN
fnp-3528	254	203	(	(	PUNCT
fnp-3528	254	204	compactin),412	compactin),412	X
fnp-3528	254	205	pravastatin,431	pravastatin,431	NOUN
fnp-3528	254	206	and	and	CCONJ
fnp-3528	254	207	rosuvastatin431,441	rosuvastatin431,441	NOUN
fnp-3528	254	208	reduced	reduce	VERB
fnp-3528	254	209	abca1	abca1	NOUN
fnp-3528	254	210	/	/	SYM
fnp-3528	254	211	abca1	abca1	NOUN
fnp-3528	254	212	mrna312,431	mrna312,431	NOUN
fnp-3528	254	213	and	and	CCONJ
fnp-3528	254	214	abca1	abca1	PROPN
fnp-3528	254	215	protein431	protein431	PROPN
fnp-3528	254	216	levels	level	NOUN
fnp-3528	254	217	.	.	PUNCT
fnp-3528	255	1	these	these	DET
fnp-3528	255	2	findings	finding	NOUN
fnp-3528	255	3	are	be	AUX
fnp-3528	255	4	expected	expect	VERB
fnp-3528	255	5	given	give	VERB
fnp-3528	255	6	that	that	SCONJ
fnp-3528	255	7	the	the	DET
fnp-3528	255	8	loss	loss	NOUN
fnp-3528	255	9	of	of	ADP
fnp-3528	255	10	cholesterol	cholesterol	NOUN
fnp-3528	255	11	by	by	ADP
fnp-3528	255	12	interruption	interruption	NOUN
fnp-3528	255	13	of	of	ADP
fnp-3528	255	14	cholesterol	cholesterol	NOUN
fnp-3528	255	15	synthesis	synthesis	NOUN
fnp-3528	255	16	leads	lead	VERB
fnp-3528	255	17	to	to	ADP
fnp-3528	255	18	a	a	DET
fnp-3528	255	19	compensatory	compensatory	ADJ
fnp-3528	255	20	reduction	reduction	NOUN
fnp-3528	255	21	of	of	ADP
fnp-3528	255	22	cholesterol	cholesterol	NOUN
fnp-3528	255	23	efflux.314384,412	efflux.314384,412	PUNCT
fnp-3528	255	24	the	the	DET
fnp-3528	255	25	contradictory	contradictory	ADJ
fnp-3528	255	26	results	result	NOUN
fnp-3528	255	27	relating	relate	VERB
fnp-3528	255	28	to	to	ADP
fnp-3528	255	29	abca1	abca1	NOUN
fnp-3528	255	30	may	may	AUX
fnp-3528	255	31	be	be	AUX
fnp-3528	255	32	caused	cause	VERB
fnp-3528	255	33	by	by	ADP
fnp-3528	255	34	the	the	DET
fnp-3528	255	35	use	use	NOUN
fnp-3528	255	36	of	of	ADP
fnp-3528	255	37	variable	variable	ADJ
fnp-3528	255	38	experimental	experimental	ADJ
fnp-3528	255	39	conditions	condition	NOUN
fnp-3528	255	40	between	between	ADP
fnp-3528	255	41	studies	study	NOUN
fnp-3528	255	42	,	,	PUNCT
fnp-3528	255	43	such	such	ADJ
fnp-3528	255	44	as	as	ADP
fnp-3528	255	45	different	different	ADJ
fnp-3528	255	46	cell	cell	NOUN
fnp-3528	255	47	lines	line	NOUN
fnp-3528	255	48	,	,	PUNCT
fnp-3528	255	49	assay	assay	NOUN
fnp-3528	255	50	methodologies	methodology	NOUN
fnp-3528	255	51	,	,	PUNCT
fnp-3528	255	52	or	or	CCONJ
fnp-3528	255	53	small	small	ADJ
fnp-3528	255	54	-	-	PUNCT
fnp-3528	255	55	molecule	molecule	NOUN
fnp-3528	255	56	-	-	PUNCT
fnp-3528	255	57	related	relate	VERB
fnp-3528	255	58	aspects	aspect	NOUN
fnp-3528	255	59	,	,	PUNCT
fnp-3528	255	60	such	such	ADJ
fnp-3528	255	61	as	as	ADP
fnp-3528	255	62	concentration	concentration	NOUN
fnp-3528	255	63	,	,	PUNCT
fnp-3528	255	64	distribution	distribution	NOUN
fnp-3528	255	65	,	,	PUNCT
fnp-3528	255	66	and	and	CCONJ
fnp-3528	255	67	protein	protein	NOUN
fnp-3528	255	68	binding	binding	NOUN
fnp-3528	255	69	.	.	PUNCT
fnp-3528	256	1	finally	finally	ADV
fnp-3528	256	2	,	,	PUNCT
fnp-3528	256	3	a	a	DET
fnp-3528	256	4	similar	similar	ADJ
fnp-3528	256	5	interconnection	interconnection	NOUN
fnp-3528	256	6	between	between	ADP
fnp-3528	256	7	hmg	hmg	NOUN
fnp-3528	256	8	-	-	PUNCT
fnp-3528	256	9	coa	coa	NOUN
fnp-3528	256	10	and	and	CCONJ
fnp-3528	256	11	abca1	abca1	NOUN
fnp-3528	256	12	was	be	AUX
fnp-3528	256	13	drawn	draw	VERB
fnp-3528	256	14	for	for	ADP
fnp-3528	256	15	the	the	DET
fnp-3528	256	16	antineoplastic	antineoplastic	ADJ
fnp-3528	256	17	agent	agent	NOUN
fnp-3528	256	18	mitotane	mitotane	NOUN
fnp-3528	256	19	,	,	PUNCT
fnp-3528	256	20	which	which	PRON
fnp-3528	256	21	downregulated	downregulate	VERB
fnp-3528	256	22	abca1	abca1	NOUN
fnp-3528	256	23	mrna441	mrna441	PROPN
fnp-3528	256	24	and	and	CCONJ
fnp-3528	256	25	increased	increase	VERB
fnp-3528	256	26	intracellular	intracellular	ADJ
fnp-3528	256	27	cholesterol	cholesterol	NOUN
fnp-3528	256	28	levels.333,441	levels.333,441	PROPN
fnp-3528	256	29	however	however	ADV
fnp-3528	256	30	,	,	PUNCT
fnp-3528	256	31	mitotane	mitotane	ADJ
fnp-3528	256	32	in	in	ADP
fnp-3528	256	33	combination	combination	NOUN
fnp-3528	256	34	with	with	ADP
fnp-3528	256	35	lxr	lxr	ADJ
fnp-3528	256	36	antagonists	antagonist	NOUN
fnp-3528	256	37	and	and	CCONJ
fnp-3528	256	38	lxr	lxr	ADJ
fnp-3528	256	39	downregulators	downregulator	NOUN
fnp-3528	256	40	had	have	VERB
fnp-3528	256	41	an	an	DET
fnp-3528	256	42	inverse	inverse	ADJ
fnp-3528	256	43	effect	effect	NOUN
fnp-3528	256	44	on	on	ADP
fnp-3528	256	45	mrna	mrna	PROPN
fnp-3528	256	46	regulation	regulation	PROPN
fnp-3528	256	47	,	,	PUNCT
fnp-3528	256	48	increasing	increase	VERB
fnp-3528	256	49	abca1	abca1	PROPN
fnp-3528	256	50	expression.327	expression.327	PROPN
fnp-3528	256	51	pkc	pkc	PROPN
fnp-3528	256	52	pathway	pathway	NOUN
fnp-3528	256	53	intrinsic	intrinsic	ADJ
fnp-3528	256	54	substrates	substrate	NOUN
fnp-3528	256	55	interestingly	interestingly	ADV
fnp-3528	256	56	,	,	PUNCT
fnp-3528	256	57	it	it	PRON
fnp-3528	256	58	was	be	AUX
fnp-3528	256	59	also	also	ADV
fnp-3528	256	60	demonstrated	demonstrate	VERB
fnp-3528	256	61	that	that	SCONJ
fnp-3528	256	62	long	long	ADJ
fnp-3528	256	63	-	-	PUNCT
fnp-3528	256	64	term	term	NOUN
fnp-3528	256	65	exposure	exposure	NOUN
fnp-3528	256	66	to	to	ADP
fnp-3528	256	67	low	low	ADJ
fnp-3528	256	68	concentrations	concentration	NOUN
fnp-3528	256	69	of	of	ADP
fnp-3528	256	70	8	8	NUM
fnp-3528	256	71	-	-	PUNCT
fnp-3528	256	72	br	br	NOUN
fnp-3528	256	73	-	-	PUNCT
fnp-3528	256	74	camp	camp	NOUN
fnp-3528	256	75	,	,	PUNCT
fnp-3528	256	76	a	a	DET
fnp-3528	256	77	standard	standard	ADJ
fnp-3528	256	78	abca1	abca1	NOUN
fnp-3528	256	79	/	/	SYM
fnp-3528	256	80	abca1	abca1	NOUN
fnp-3528	256	81	inducer,230,249,255,266,290,292	inducer,230,249,255,266,290,292	CCONJ
fnp-3528	256	82	led	lead	VERB
fnp-3528	256	83	to	to	PART
fnp-3528	256	84	decreased	decrease	VERB
fnp-3528	256	85	apoe	apoe	ADJ
fnp-3528	256	86	secretion	secretion	NOUN
fnp-3528	256	87	from	from	ADP
fnp-3528	256	88	human	human	ADJ
fnp-3528	256	89	monocyte	monocyte	NOUN
fnp-3528	256	90	-	-	PUNCT
fnp-3528	256	91	derived	derive	VERB
fnp-3528	256	92	macrophages.266	macrophages.266	NOUN
fnp-3528	256	93	apoe	apoe	NOUN
fnp-3528	256	94	secretion	secretion	NOUN
fnp-3528	256	95	can	can	AUX
fnp-3528	256	96	be	be	AUX
fnp-3528	256	97	considered	consider	VERB
fnp-3528	256	98	as	as	ADP
fnp-3528	256	99	a	a	DET
fnp-3528	256	100	surrogate	surrogate	ADJ
fnp-3528	256	101	marker	marker	NOUN
fnp-3528	256	102	for	for	ADP
fnp-3528	256	103	abca1	abca1	NOUN
fnp-3528	256	104	-	-	PUNCT
fnp-3528	256	105	mediated	mediate	VERB
fnp-3528	256	106	cholesterol	cholesterol	NOUN
fnp-3528	256	107	transport	transport	NOUN
fnp-3528	256	108	.	.	PUNCT
fnp-3528	257	1	ppar	ppar	NOUN
fnp-3528	257	2	pathway	pathway	NOUN
fnp-3528	257	3	–	–	PUNCT
fnp-3528	257	4	pharmacological	pharmacological	ADJ
fnp-3528	257	5	drugs	drug	NOUN
fnp-3528	257	6	and	and	CCONJ
fnp-3528	257	7	synthetic	synthetic	ADJ
fnp-3528	257	8	compounds	compound	NOUN
fnp-3528	257	9	regarding	regard	VERB
fnp-3528	257	10	the	the	DET
fnp-3528	257	11	important	important	ADJ
fnp-3528	257	12	ppar	ppar	NOUN
fnp-3528	257	13	pathway	pathway	NOUN
fnp-3528	257	14	,	,	PUNCT
fnp-3528	257	15	it	it	PRON
fnp-3528	257	16	must	must	AUX
fnp-3528	257	17	be	be	AUX
fnp-3528	257	18	noted	note	VERB
fnp-3528	257	19	that	that	SCONJ
fnp-3528	257	20	troglitazone	troglitazone	NOUN
fnp-3528	257	21	,	,	PUNCT
fnp-3528	257	22	indicated	indicate	VERB
fnp-3528	257	23	above	above	ADV
fnp-3528	257	24	as	as	SCONJ
fnp-3528	257	25	an	an	DET
fnp-3528	257	26	abca1	abca1	NOUN
fnp-3528	257	27	inducer,268	inducer,268	PROPN
fnp-3528	257	28	was	be	AUX
fnp-3528	257	29	also	also	ADV
fnp-3528	257	30	reported	report	VERB
fnp-3528	257	31	to	to	ADP
fnp-3528	257	32	downregulate	downregulate	PROPN
fnp-3528	257	33	abca1	abca1	PROPN
fnp-3528	257	34	transcription.321	transcription.321	NOUN
fnp-3528	257	35	these	these	DET
fnp-3528	257	36	inconsistent	inconsistent	ADJ
fnp-3528	257	37	effects	effect	NOUN
fnp-3528	257	38	may	may	AUX
fnp-3528	257	39	be	be	AUX
fnp-3528	257	40	explained	explain	VERB
fnp-3528	257	41	partially	partially	ADV
fnp-3528	257	42	by	by	ADP
fnp-3528	257	43	the	the	DET
fnp-3528	257	44	different	different	ADJ
fnp-3528	257	45	concentrations	concentration	NOUN
fnp-3528	257	46	used	use	VERB
fnp-3528	257	47	(	(	PUNCT
fnp-3528	257	48	1	1	NUM
fnp-3528	257	49	μm	μm	NOUN
fnp-3528	257	50	vs	vs	ADP
fnp-3528	257	51	10	10	NUM
fnp-3528	257	52	μm),268,321	μm),268,321	NUM
fnp-3528	257	53	but	but	CCONJ
fnp-3528	257	54	may	may	AUX
fnp-3528	257	55	also	also	ADV
fnp-3528	257	56	be	be	AUX
fnp-3528	257	57	related	relate	VERB
fnp-3528	257	58	to	to	ADP
fnp-3528	257	59	cross	cross	VERB
fnp-3528	257	60	-	-	NOUN
fnp-3528	257	61	talk	talk	NOUN
fnp-3528	257	62	between	between	ADP
fnp-3528	257	63	the	the	DET
fnp-3528	257	64	ppar	ppar	NOUN
fnp-3528	257	65	,	,	PUNCT
fnp-3528	257	66	lxr	lxr	PROPN
fnp-3528	257	67	,	,	PUNCT
fnp-3528	257	68	and	and	CCONJ
fnp-3528	257	69	mevalonate	mevalonate	VERB
fnp-3528	257	70	pathways	pathway	NOUN
fnp-3528	257	71	.	.	PUNCT
fnp-3528	258	1	the	the	DET
fnp-3528	258	2	ppar	ppar	NOUN
fnp-3528	258	3	-	-	PUNCT
fnp-3528	258	4	γ	γ	NOUN
fnp-3528	258	5	antagonist	antagonist	NOUN
fnp-3528	258	6	gw9662	gw9662	PROPN
fnp-3528	258	7	(	(	PUNCT
fnp-3528	258	8	figure	figure	NOUN
fnp-3528	258	9	 	 	SPACE
fnp-3528	258	10	2	2	NUM
fnp-3528	258	11	)	)	PUNCT
fnp-3528	258	12	reduced	reduce	VERB
fnp-3528	258	13	abca1	abca1	NOUN
fnp-3528	258	14	protein	protein	NOUN
fnp-3528	258	15	levels.406	levels.406	VERB
fnp-3528	258	16	other	other	ADJ
fnp-3528	258	17	abca1	abca1	NOUN
fnp-3528	258	18	downregulators	downregulator	NOUN
fnp-3528	258	19	–	–	PUNCT
fnp-3528	258	20	natural	natural	ADJ
fnp-3528	258	21	compounds	compound	VERB
fnp-3528	258	22	other	other	ADJ
fnp-3528	258	23	small	small	ADJ
fnp-3528	258	24	-	-	PUNCT
fnp-3528	258	25	molecules	molecule	NOUN
fnp-3528	258	26	have	have	AUX
fnp-3528	258	27	been	be	AUX
fnp-3528	258	28	reported	report	VERB
fnp-3528	258	29	to	to	PART
fnp-3528	258	30	act	act	VERB
fnp-3528	258	31	as	as	ADP
fnp-3528	258	32	abca1	abca1	NOUN
fnp-3528	258	33	/	/	SYM
fnp-3528	258	34	abca1	abca1	NOUN
fnp-3528	258	35	downregulators	downregulator	NOUN
fnp-3528	258	36	,	,	PUNCT
fnp-3528	258	37	acting	act	VERB
fnp-3528	258	38	independently	independently	ADV
fnp-3528	258	39	of	of	ADP
fnp-3528	258	40	the	the	DET
fnp-3528	258	41	previously	previously	ADV
fnp-3528	258	42	mentioned	mention	VERB
fnp-3528	258	43	lxr	lxr	PROPN
fnp-3528	258	44	,	,	PUNCT
fnp-3528	258	45	rxr	rxr	PROPN
fnp-3528	258	46	,	,	PUNCT
fnp-3528	258	47	ppar	ppar	NOUN
fnp-3528	258	48	,	,	PUNCT
fnp-3528	258	49	and	and	CCONJ
fnp-3528	258	50	hmg	hmg	NOUN
fnp-3528	258	51	-	-	PUNCT
fnp-3528	258	52	coa	coa	NOUN
fnp-3528	258	53	-	-	PUNCT
fnp-3528	258	54	reductase	reductase	NOUN
fnp-3528	258	55	pathways	pathway	NOUN
fnp-3528	258	56	.	.	PUNCT
fnp-3528	259	1	natural	natural	ADJ
fnp-3528	259	2	compounds	compound	NOUN
fnp-3528	259	3	such	such	ADJ
fnp-3528	259	4	as	as	ADP
fnp-3528	259	5	α	α	PROPN
fnp-3528	259	6	,	,	PUNCT
fnp-3528	259	7	β	β	ADJ
fnp-3528	259	8	-	-	ADJ
fnp-3528	259	9	unsaturated	unsaturated	ADJ
fnp-3528	259	10	carbonyl	carbonyl	NOUN
fnp-3528	259	11	derivative	derivative	NOUN
fnp-3528	259	12	acrolein,442	acrolein,442	NOUN
fnp-3528	259	13	the	the	DET
fnp-3528	259	14	polyphenol	polyphenol	NOUN
fnp-3528	259	15	bisphenol	bisphenol	NOUN
fnp-3528	259	16	a,443	a,443	NOUN
fnp-3528	259	17	and	and	CCONJ
fnp-3528	259	18	the	the	DET
fnp-3528	259	19	polyphenol	polyphenol	NOUN
fnp-3528	259	20	1,2,3,4,6	1,2,3,4,6	NUM
fnp-3528	259	21	penta	penta	ADJ
fnp-3528	259	22	-	-	PUNCT
fnp-3528	259	23	o	o	NOUN
fnp-3528	259	24	-	-	ADJ
fnp-3528	259	25	galloyl	galloyl	ADJ
fnp-3528	259	26	-	-	PUNCT
fnp-3528	259	27	β	β	NOUN
fnp-3528	259	28	-	-	PUNCT
fnp-3528	259	29	d	d	NOUN
fnp-3528	259	30	-	-	PUNCT
fnp-3528	259	31	glucose444	glucose444	PROPN
fnp-3528	259	32	demonstrated	demonstrate	VERB
fnp-3528	259	33	an	an	DET
fnp-3528	259	34	abca1	abca1	NOUN
fnp-3528	259	35	mrna443,444	mrna443,444	ADJ
fnp-3528	259	36	and	and	CCONJ
fnp-3528	259	37	abca1	abca1	NOUN
fnp-3528	259	38	protein442	protein442	PROPN
fnp-3528	259	39	downregulation	downregulation	NOUN
fnp-3528	259	40	in	in	ADP
fnp-3528	259	41	vitro443,442	vitro443,442	VERB
fnp-3528	259	42	and	and	CCONJ
fnp-3528	259	43	in	in	ADP
fnp-3528	259	44	vivo.444	vivo.444	NUM
fnp-3528	259	45	the	the	DET
fnp-3528	259	46	effect	effect	NOUN
fnp-3528	259	47	of	of	ADP
fnp-3528	259	48	acrolein	acrolein	PROPN
fnp-3528	259	49	could	could	AUX
fnp-3528	259	50	be	be	AUX
fnp-3528	259	51	abrogated	abrogate	VERB
fnp-3528	259	52	by	by	ADP
fnp-3528	259	53	3	3	NUM
fnp-3528	259	54	-	-	PUNCT
fnp-3528	259	55	hydroxytyrosol,442	hydroxytyrosol,442	PROPN
fnp-3528	259	56	an	an	DET
fnp-3528	259	57	inducer	inducer	NOUN
fnp-3528	259	58	of	of	ADP
fnp-3528	259	59	abca1	abca1	NOUN
fnp-3528	259	60	protein	protein	NOUN
fnp-3528	259	61	content.445	content.445	PROPN
fnp-3528	259	62	srebp2	srebp2	PROPN
fnp-3528	259	63	has	have	AUX
fnp-3528	259	64	been	be	AUX
fnp-3528	259	65	demonstrated	demonstrate	VERB
fnp-3528	259	66	to	to	PART
fnp-3528	259	67	be	be	AUX
fnp-3528	259	68	targeted	target	VERB
fnp-3528	259	69	by	by	ADP
fnp-3528	259	70	egcg	egcg	NOUN
fnp-3528	259	71	in	in	ADP
fnp-3528	259	72	high	high	ADJ
fnp-3528	259	73	fat	fat	ADJ
fnp-3528	259	74	diet	diet	NOUN
fnp-3528	259	75	-	-	PUNCT
fnp-3528	259	76	fed	feed	VERB
fnp-3528	259	77	transgenic	transgenic	NOUN
fnp-3528	259	78	srebp+/+	srebp+/+	PROPN
fnp-3528	259	79	wistar	wistar	PROPN
fnp-3528	259	80	rats	rat	NOUN
fnp-3528	259	81	,	,	PUNCT
fnp-3528	259	82	resulting	result	VERB
fnp-3528	259	83	in	in	ADP
fnp-3528	259	84	abca1	abca1	PROPN
fnp-3528	259	85	mrna	mrna	NOUN
fnp-3528	259	86	downregulation	downregulation	NOUN
fnp-3528	259	87	,	,	PUNCT
fnp-3528	259	88	while	while	SCONJ
fnp-3528	259	89	an	an	DET
fnp-3528	259	90	abca1	abca1	NOUN
fnp-3528	259	91	mrna	mrna	PROPN
fnp-3528	259	92	upregulation	upregulation	NOUN
fnp-3528	259	93	could	could	AUX
fnp-3528	259	94	be	be	AUX
fnp-3528	259	95	observed	observe	VERB
fnp-3528	259	96	under	under	ADP
fnp-3528	259	97	the	the	DET
fnp-3528	259	98	same	same	ADJ
fnp-3528	259	99	conditions	condition	NOUN
fnp-3528	259	100	in	in	ADP
fnp-3528	259	101	srebp	srebp	ADJ
fnp-3528	259	102	knock	knock	NOUN
fnp-3528	259	103	-	-	PUNCT
fnp-3528	259	104	out	out	NOUN
fnp-3528	259	105	wistar	wistar	PROPN
fnp-3528	259	106	rats.446	rats.446	PROPN
fnp-3528	259	107	other	other	ADJ
fnp-3528	259	108	abca1	abca1	NOUN
fnp-3528	259	109	downregulators	downregulator	NOUN
fnp-3528	259	110	–	–	PUNCT
fnp-3528	259	111	pharmacological	pharmacological	ADJ
fnp-3528	259	112	drugs	drug	NOUN
fnp-3528	259	113	exposure	exposure	NOUN
fnp-3528	259	114	of	of	ADP
fnp-3528	259	115	the	the	DET
fnp-3528	259	116	human	human	ADJ
fnp-3528	259	117	non	non	ADJ
fnp-3528	259	118	-	-	ADJ
fnp-3528	259	119	small	small	ADJ
fnp-3528	259	120	cell	cell	NOUN
fnp-3528	259	121	lung	lung	NOUN
fnp-3528	259	122	cancer	cancer	NOUN
fnp-3528	259	123	lines	line	NOUN
fnp-3528	259	124	a549	a549	PROPN
fnp-3528	259	125	and	and	CCONJ
fnp-3528	259	126	h358	h358	PROPN
fnp-3528	259	127	to	to	ADP
fnp-3528	259	128	the	the	DET
fnp-3528	259	129	antiepileptic	antiepileptic	ADJ
fnp-3528	259	130	drug	drug	NOUN
fnp-3528	259	131	valproate	valproate	NOUN
fnp-3528	259	132	led	lead	VERB
fnp-3528	259	133	to	to	ADP
fnp-3528	259	134	downregulation	downregulation	NOUN
fnp-3528	259	135	of	of	ADP
fnp-3528	259	136	abca1	abca1	PROPN
fnp-3528	259	137	mrna	mrna	PROPN
fnp-3528	259	138	and	and	CCONJ
fnp-3528	259	139	abca1	abca1	NOUN
fnp-3528	259	140	protein	protein	NOUN
fnp-3528	259	141	levels	level	NOUN
fnp-3528	259	142	through	through	ADP
fnp-3528	259	143	a	a	DET
fnp-3528	259	144	histone	histone	NOUN
fnp-3528	259	145	deacetylase	deacetylase	NOUN
fnp-3528	259	146	2-(hdac2)-mediated	2-(hdac2)-mediate	VERB
fnp-3528	259	147	mechanism	mechanism	NOUN
fnp-3528	259	148	.	.	PUNCT
fnp-3528	260	1	in	in	ADP
fnp-3528	260	2	parallel	parallel	NOUN
fnp-3528	260	3	,	,	PUNCT
fnp-3528	260	4	the	the	DET
fnp-3528	260	5	authors	author	NOUN
fnp-3528	260	6	observed	observe	VERB
fnp-3528	260	7	an	an	DET
fnp-3528	260	8	increased	increase	VERB
fnp-3528	260	9	sensitivity	sensitivity	NOUN
fnp-3528	260	10	of	of	ADP
fnp-3528	260	11	these	these	DET
fnp-3528	260	12	cells	cell	NOUN
fnp-3528	260	13	to	to	PART
fnp-3528	260	14	cisplatin.447	cisplatin.447	VERB
fnp-3528	260	15	the	the	DET
fnp-3528	260	16	selective	selective	ADJ
fnp-3528	260	17	estrogen	estrogen	NOUN
fnp-3528	260	18	receptor	receptor	NOUN
fnp-3528	260	19	modulators	modulator	NOUN
fnp-3528	260	20	raloxifene	raloxifene	VERB
fnp-3528	260	21	,	,	PUNCT
fnp-3528	260	22	tamoxifen	tamoxifen	NOUN
fnp-3528	260	23	,	,	PUNCT
fnp-3528	260	24	and	and	CCONJ
fnp-3528	260	25	toremifene	toremifene	NOUN
fnp-3528	260	26	were	be	AUX
fnp-3528	260	27	reported	report	VERB
fnp-3528	260	28	to	to	PART
fnp-3528	260	29	reduce	reduce	VERB
fnp-3528	260	30	abca1	abca1	NOUN
fnp-3528	260	31	protein	protein	NOUN
fnp-3528	260	32	content	content	NOUN
fnp-3528	260	33	in	in	ADP
fnp-3528	260	34	thp-1	thp-1	PUNCT
fnp-3528	260	35	macrophages	macrophage	NOUN
fnp-3528	260	36	along	along	ADV
fnp-3528	260	37	with	with	ADP
fnp-3528	260	38	decreased	decrease	VERB
fnp-3528	260	39	cholesterol	cholesterol	NOUN
fnp-3528	260	40	efflux	efflux	NOUN
fnp-3528	260	41	and	and	CCONJ
fnp-3528	260	42	increased	increase	VERB
fnp-3528	260	43	intracellular	intracellular	ADJ
fnp-3528	260	44	cholesterol	cholesterol	NOUN
fnp-3528	260	45	levels.341	levels.341	NOUN
fnp-3528	260	46	tamoxifen	tamoxifen	NOUN
fnp-3528	260	47	and	and	CCONJ
fnp-3528	260	48	raloxifene	raloxifene	NOUN
fnp-3528	260	49	treatment	treatment	NOUN
fnp-3528	260	50	decreased	decrease	VERB
fnp-3528	260	51	serum	serum	PROPN
fnp-3528	260	52	hdl	hdl	PROPN
fnp-3528	260	53	-	-	PUNCT
fnp-3528	260	54	cholesterol	cholesterol	NOUN
fnp-3528	260	55	levels	level	NOUN
fnp-3528	260	56	in	in	ADP
fnp-3528	260	57	mice	mouse	NOUN
fnp-3528	260	58	.	.	PUNCT
fnp-3528	261	1	in	in	ADP
fnp-3528	261	2	addition	addition	NOUN
fnp-3528	261	3	,	,	PUNCT
fnp-3528	261	4	tamoxifen	tamoxifen	NOUN
fnp-3528	261	5	reduced	reduce	VERB
fnp-3528	261	6	cholesterol	cholesterol	NOUN
fnp-3528	261	7	levels	level	NOUN
fnp-3528	261	8	in	in	ADP
fnp-3528	261	9	serum	serum	NOUN
fnp-3528	261	10	,	,	PUNCT
fnp-3528	261	11	liver	liver	NOUN
fnp-3528	261	12	,	,	PUNCT
fnp-3528	261	13	and	and	CCONJ
fnp-3528	261	14	feces	fece	NOUN
fnp-3528	261	15	of	of	ADP
fnp-3528	261	16	mice	mouse	NOUN
fnp-3528	261	17	after	after	ADP
fnp-3528	261	18	injection	injection	NOUN
fnp-3528	261	19	with	with	ADP
fnp-3528	261	20	cholesterol	cholesterol	NOUN
fnp-3528	261	21	-	-	PUNCT
fnp-3528	261	22	loaded	load	VERB
fnp-3528	261	23	macrophages.341	macrophages.341	NOUN
fnp-3528	261	24	interestingly	interestingly	ADV
fnp-3528	261	25	,	,	PUNCT
fnp-3528	261	26	the	the	DET
fnp-3528	261	27	downregulation	downregulation	NOUN
fnp-3528	261	28	of	of	ADP
fnp-3528	261	29	abca1	abca1	NOUN
fnp-3528	261	30	protein	protein	NOUN
fnp-3528	261	31	content	content	NOUN
fnp-3528	261	32	by	by	ADP
fnp-3528	261	33	these	these	DET
fnp-3528	261	34	estrogen	estrogen	NOUN
fnp-3528	261	35	receptor	receptor	NOUN
fnp-3528	261	36	modulators	modulator	NOUN
fnp-3528	261	37	could	could	AUX
fnp-3528	261	38	not	not	PART
fnp-3528	261	39	be	be	AUX
fnp-3528	261	40	demonstrated	demonstrate	VERB
fnp-3528	261	41	for	for	ADP
fnp-3528	261	42	murine	murine	ADJ
fnp-3528	261	43	liver	liver	NOUN
fnp-3528	261	44	,	,	PUNCT
fnp-3528	261	45	indicating	indicate	VERB
fnp-3528	261	46	a	a	DET
fnp-3528	261	47	macrophage	macrophage	NOUN
fnp-3528	261	48	-	-	PUNCT
fnp-3528	261	49	specific	specific	ADJ
fnp-3528	261	50	effect.341	effect.341	NOUN
fnp-3528	261	51	varenicline	varenicline	NOUN
fnp-3528	261	52	,	,	PUNCT
fnp-3528	261	53	a	a	DET
fnp-3528	261	54	drug	drug	NOUN
fnp-3528	261	55	used	use	VERB
fnp-3528	261	56	in	in	ADP
fnp-3528	261	57	smoking	smoking	NOUN
fnp-3528	261	58	cessation	cessation	NOUN
fnp-3528	261	59	,	,	PUNCT
fnp-3528	261	60	was	be	AUX
fnp-3528	261	61	shown	show	VERB
fnp-3528	261	62	in	in	ADP
fnp-3528	261	63	vivo	vivo	NOUN
fnp-3528	261	64	to	to	PART
fnp-3528	261	65	promote	promote	VERB
fnp-3528	261	66	aortic	aortic	ADJ
fnp-3528	261	67	atherosclerotic	atherosclerotic	ADJ
fnp-3528	261	68	lesions	lesion	NOUN
fnp-3528	261	69	in	in	ADP
fnp-3528	261	70	apoe	apoe	ADJ
fnp-3528	261	71	knock	knock	NOUN
fnp-3528	261	72	-	-	PUNCT
fnp-3528	261	73	out	out	ADP
fnp-3528	261	74	c57bl/6	c57bl/6	NOUN
fnp-3528	261	75	mice.417,448	mice.417,448	NOUN
fnp-3528	261	76	the	the	DET
fnp-3528	261	77	authors	author	NOUN
fnp-3528	261	78	demonstrated	demonstrate	VERB
fnp-3528	261	79	that	that	SCONJ
fnp-3528	261	80	intracellular	intracellular	ADJ
fnp-3528	261	81	lipid	lipid	NOUN
fnp-3528	261	82	content	content	NOUN
fnp-3528	261	83	in	in	ADP
fnp-3528	261	84	peritoneal	peritoneal	ADJ
fnp-3528	261	85	macrophages	macrophage	NOUN
fnp-3528	261	86	was	be	AUX
fnp-3528	261	87	increased	increase	VERB
fnp-3528	261	88	,	,	PUNCT
fnp-3528	261	89	and	and	CCONJ
fnp-3528	261	90	a	a	DET
fnp-3528	261	91	decreased	decrease	VERB
fnp-3528	261	92	abca1	abca1	NOUN
fnp-3528	261	93	protein	protein	NOUN
fnp-3528	261	94	expression	expression	NOUN
fnp-3528	261	95	was	be	AUX
fnp-3528	261	96	confirmed	confirm	VERB
fnp-3528	261	97	in	in	ADP
fnp-3528	261	98	vitro	vitro	X
fnp-3528	261	99	in	in	ADP
fnp-3528	261	100	raw264.7	raw264.7	PROPN
fnp-3528	261	101	macrophages	macrophage	NOUN
fnp-3528	261	102	.	.	PUNCT
fnp-3528	262	1	finally	finally	ADV
fnp-3528	262	2	,	,	PUNCT
fnp-3528	262	3	the	the	DET
fnp-3528	262	4	antineoplastic	antineoplastic	ADJ
fnp-3528	262	5	agent	agent	NOUN
fnp-3528	262	6	gefitinib	gefitinib	NOUN
fnp-3528	262	7	reduced	reduce	VERB
fnp-3528	262	8	abca1	abca1	NOUN
fnp-3528	262	9	protein	protein	NOUN
fnp-3528	262	10	content	content	NOUN
fnp-3528	262	11	in	in	ADP
fnp-3528	262	12	various	various	ADJ
fnp-3528	262	13	non	non	ADJ
fnp-3528	262	14	-	-	ADJ
fnp-3528	262	15	small	small	ADJ
fnp-3528	262	16	cell	cell	NOUN
fnp-3528	262	17	lung	lung	NOUN
fnp-3528	262	18	cancer	cancer	NOUN
fnp-3528	262	19	cell	cell	NOUN
fnp-3528	262	20	lines.400	lines.400	VERB
fnp-3528	262	21	other	other	ADJ
fnp-3528	262	22	abca1	abca1	NOUN
fnp-3528	262	23	downregulators	downregulator	NOUN
fnp-3528	262	24	–	–	PUNCT
fnp-3528	262	25	synthetic	synthetic	NOUN
fnp-3528	262	26	compounds	compound	VERB
fnp-3528	262	27	the	the	DET
fnp-3528	262	28	plasticizer	plasticizer	NOUN
fnp-3528	262	29	dibutyl	dibutyl	NOUN
fnp-3528	262	30	phthalate389	phthalate389	PROPN
fnp-3528	262	31	and	and	CCONJ
fnp-3528	262	32	the	the	DET
fnp-3528	262	33	pi3k	pi3k	PROPN
fnp-3528	262	34	/	/	SYM
fnp-3528	262	35	akt	akt	PROPN
fnp-3528	262	36	inhibitor	inhibitor	PROPN
fnp-3528	262	37	ly294002421	ly294002421	PROPN
fnp-3528	262	38	reduced	reduce	VERB
fnp-3528	262	39	abca1	abca1	PROPN
fnp-3528	263	1	mrna389	mrna389	PROPN
fnp-3528	263	2	and	and	CCONJ
fnp-3528	263	3	abca1	abca1	NOUN
fnp-3528	263	4	protein389,421	protein389,421	NOUN
fnp-3528	263	5	expression	expression	NOUN
fnp-3528	263	6	and	and	CCONJ
fnp-3528	263	7	increased	increase	VERB
fnp-3528	263	8	cellular	cellular	ADJ
fnp-3528	263	9	cholesterol	cholesterol	NOUN
fnp-3528	263	10	and	and	CCONJ
fnp-3528	263	11	lipid	lipid	NOUN
fnp-3528	263	12	levels389	levels389	PROPN
fnp-3528	263	13	in	in	ADP
fnp-3528	263	14	human389	human389	PROPN
fnp-3528	263	15	and	and	CCONJ
fnp-3528	263	16	murine421	murine421	PROPN
fnp-3528	263	17	macrophages	macrophage	NOUN
fnp-3528	263	18	.	.	PUNCT
fnp-3528	264	1	the	the	DET
fnp-3528	264	2	sphingosine	sphingosine	PROPN
fnp-3528	264	3	kinase	kinase	PROPN
fnp-3528	264	4	1	1	NUM
fnp-3528	264	5	and	and	CCONJ
fnp-3528	264	6	2	2	NUM
fnp-3528	264	7	inhibitor	inhibitor	NOUN
fnp-3528	264	8	4-{[4-(4	4-{[4-(4	NUM
fnp-3528	264	9	-	-	PUNCT
fnp-3528	264	10	chlorophenyl)-2	chlorophenyl)-2	PROPN
fnp-3528	264	11	-	-	PUNCT
fnp-3528	264	12	thiazolyl]amino}phenol	thiazolyl]amino}phenol	PROPN
fnp-3528	264	13	was	be	AUX
fnp-3528	264	14	demonstrated	demonstrate	VERB
fnp-3528	264	15	to	to	ADP
fnp-3528	264	16	downregulate	downregulate	NOUN
fnp-3528	264	17	abca1	abca1	NOUN
fnp-3528	264	18	protein	protein	NOUN
fnp-3528	264	19	expression	expression	NOUN
fnp-3528	264	20	in	in	ADP
fnp-3528	264	21	murine	murine	ADJ
fnp-3528	264	22	primary	primary	ADJ
fnp-3528	264	23	macrophages	macrophage	NOUN
fnp-3528	264	24	,	,	PUNCT
fnp-3528	264	25	which	which	PRON
fnp-3528	264	26	was	be	AUX
fnp-3528	264	27	dependent	dependent	ADJ
fnp-3528	264	28	on	on	ADP
fnp-3528	264	29	the	the	DET
fnp-3528	264	30	sphingosine	sphingosine	NOUN
fnp-3528	264	31	kinase	kinase	PROPN
fnp-3528	264	32	2	2	NUM
fnp-3528	264	33	as	as	ADV
fnp-3528	264	34	well	well	ADV
fnp-3528	264	35	as	as	ADP
fnp-3528	265	1	the	the	DET
fnp-3528	265	2	sphingosine-1	sphingosine-1	ADV
fnp-3528	265	3	-	-	PUNCT
fnp-3528	265	4	phosphate	phosphate	NOUN
fnp-3528	265	5	receptor.306	receptor.306	NOUN
fnp-3528	265	6	this	this	DET
fnp-3528	265	7	abca1	abca1	NOUN
fnp-3528	265	8	protein	protein	NOUN
fnp-3528	265	9	downregulation	downregulation	NOUN
fnp-3528	265	10	was	be	AUX
fnp-3528	265	11	accompanied	accompany	VERB
fnp-3528	265	12	by	by	ADP
fnp-3528	265	13	a	a	DET
fnp-3528	265	14	reduced	reduce	VERB
fnp-3528	265	15	cholesterol	cholesterol	NOUN
fnp-3528	265	16	efflux	efflux	NOUN
fnp-3528	265	17	.	.	PUNCT
fnp-3528	266	1	the	the	DET
fnp-3528	266	2	acyl	acyl	NOUN
fnp-3528	266	3	coenzyme	coenzyme	PROPN
fnp-3528	266	4	a	a	DET
fnp-3528	266	5	cholesteryl	cholesteryl	PROPN
fnp-3528	266	6	acyl	acyl	X
fnp-3528	266	7	transferase	transferase	NOUN
fnp-3528	266	8	(	(	PUNCT
fnp-3528	266	9	acat	acat	ADJ
fnp-3528	266	10	)	)	PUNCT
fnp-3528	266	11	inhibitor	inhibitor	NOUN
fnp-3528	266	12	atr-101	atr-101	NOUN
fnp-3528	266	13	reduced	reduce	VERB
fnp-3528	266	14	abca1	abca1	PROPN
fnp-3528	266	15	mrna	mrna	PROPN
fnp-3528	266	16	levels	level	NOUN
fnp-3528	267	1	and	and	CCONJ
fnp-3528	268	1	induced	induce	VERB
fnp-3528	268	2	an	an	DET
fnp-3528	268	3	increase	increase	NOUN
fnp-3528	268	4	in	in	ADP
fnp-3528	268	5	intracellular	intracellular	ADJ
fnp-3528	268	6	cholesterol	cholesterol	NOUN
fnp-3528	268	7	content	content	NOUN
fnp-3528	268	8	in	in	ADP
fnp-3528	268	9	h295r	h295r	NOUN
fnp-3528	268	10	cells.251	cells.251	NOUN
fnp-3528	268	11	the	the	DET
fnp-3528	268	12	authors	author	NOUN
fnp-3528	268	13	suggested	suggest	VERB
fnp-3528	268	14	that	that	SCONJ
fnp-3528	268	15	this	this	PRON
fnp-3528	268	16	was	be	AUX
fnp-3528	268	17	caused	cause	VERB
fnp-3528	268	18	by	by	ADP
fnp-3528	268	19	inhibition	inhibition	NOUN
fnp-3528	268	20	of	of	ADP
fnp-3528	268	21	abca1	abca1	NOUN
fnp-3528	268	22	but	but	CCONJ
fnp-3528	268	23	provided	provide	VERB
fnp-3528	268	24	no	no	DET
fnp-3528	268	25	clear	clear	ADJ
fnp-3528	268	26	proof	proof	NOUN
fnp-3528	268	27	of	of	ADP
fnp-3528	268	28	direct	direct	ADJ
fnp-3528	268	29	inhibition	inhibition	NOUN
fnp-3528	268	30	of	of	ADP
fnp-3528	268	31	abca1	abca1	NOUN
fnp-3528	268	32	.	.	PUNCT
fnp-3528	269	1	therefore	therefore	ADV
fnp-3528	269	2	,	,	PUNCT
fnp-3528	269	3	this	this	DET
fnp-3528	269	4	compound	compound	NOUN
fnp-3528	269	5	was	be	AUX
fnp-3528	269	6	classified	classify	VERB
fnp-3528	269	7	as	as	ADP
fnp-3528	269	8	a	a	DET
fnp-3528	269	9	downregulator	downregulator	NOUN
fnp-3528	269	10	.	.	PUNCT
fnp-3528	270	1	other	other	ADJ
fnp-3528	270	2	abca	abca	PROPN
fnp-3528	270	3	transporters	transporter	NOUN
fnp-3528	270	4	abca2	abca2	ADV
fnp-3528	270	5	and	and	CCONJ
fnp-3528	270	6	abca3	abca3	PROPN
fnp-3528	270	7	compared	compare	VERB
fnp-3528	270	8	to	to	ADP
fnp-3528	270	9	abca1	abca1	NOUN
fnp-3528	270	10	,	,	PUNCT
fnp-3528	270	11	knowledge	knowledge	NOUN
fnp-3528	270	12	relating	relate	VERB
fnp-3528	270	13	to	to	ADP
fnp-3528	270	14	downregulators	downregulator	NOUN
fnp-3528	270	15	of	of	ADP
fnp-3528	270	16	the	the	DET
fnp-3528	270	17	other	other	ADJ
fnp-3528	270	18	abca	abca	NOUN
fnp-3528	270	19	transporters	transporter	NOUN
fnp-3528	270	20	is	be	AUX
fnp-3528	270	21	very	very	ADV
fnp-3528	270	22	limited	limited	ADJ
fnp-3528	270	23	.	.	PUNCT
fnp-3528	271	1	as	as	SCONJ
fnp-3528	271	2	discussed	discuss	VERB
fnp-3528	271	3	above	above	ADV
fnp-3528	271	4	,	,	PUNCT
fnp-3528	272	1	human	human	ADJ
fnp-3528	272	2	leukemia	leukemia	NOUN
fnp-3528	272	3	cells	cell	NOUN
fnp-3528	272	4	exposed	expose	VERB
fnp-3528	272	5	to	to	ADP
fnp-3528	272	6	imatinib	imatinib	NOUN
fnp-3528	272	7	displayed	display	VERB
fnp-3528	272	8	increased	increase	VERB
fnp-3528	272	9	abca2	abca2	NOUN
fnp-3528	272	10	mrna	mrna	PROPN
fnp-3528	272	11	and	and	CCONJ
fnp-3528	272	12	abca2	abca2	NOUN
fnp-3528	272	13	protein	protein	NOUN
fnp-3528	272	14	expression.236	expression.236	PROPN
fnp-3528	272	15	celecoxib	celecoxib	NOUN
fnp-3528	272	16	abrogated	abrogate	VERB
fnp-3528	272	17	this	this	PRON
fnp-3528	272	18	effect.236	effect.236	PROPN
fnp-3528	272	19	a	a	DET
fnp-3528	272	20	similar	similar	ADJ
fnp-3528	272	21	observation	observation	NOUN
fnp-3528	272	22	was	be	AUX
fnp-3528	272	23	reported	report	VERB
fnp-3528	272	24	for	for	ADP
fnp-3528	272	25	abca3	abca3	PROPN
fnp-3528	272	26	,	,	PUNCT
fnp-3528	272	27	where	where	SCONJ
fnp-3528	272	28	the	the	DET
fnp-3528	272	29	anti	anti	ADJ
fnp-3528	272	30	-	-	ADJ
fnp-3528	272	31	inflammatory	inflammatory	ADJ
fnp-3528	272	32	drug	drug	NOUN
fnp-3528	272	33	indomethacin	indomethacin	NOUN
fnp-3528	272	34	and	and	CCONJ
fnp-3528	272	35	the	the	DET
fnp-3528	272	36	abca1	abca1	NOUN
fnp-3528	272	37	inhibitor	inhibitor	NOUN
fnp-3528	273	1	sirolimus245	sirolimus245	PROPN
fnp-3528	273	2	(	(	PUNCT
fnp-3528	273	3	figure	figure	NOUN
fnp-3528	273	4	 	 	SPACE
fnp-3528	273	5	2	2	NUM
fnp-3528	273	6	)	)	PUNCT
fnp-3528	273	7	downregulated	downregulate	VERB
fnp-3528	273	8	abca3	abca3	PROPN
fnp-3528	273	9	mrna	mrna	PROPN
fnp-3528	273	10	in	in	ADP
fnp-3528	273	11	various	various	ADJ
fnp-3528	273	12	cancer	cancer	NOUN
fnp-3528	273	13	cell	cell	NOUN
fnp-3528	273	14	lines.426,449,450	lines.426,449,450	PUNCT
fnp-3528	273	15	this	this	DET
fnp-3528	273	16	treatment	treatment	NOUN
fnp-3528	273	17	also	also	ADV
fnp-3528	273	18	resulted	result	VERB
fnp-3528	273	19	in	in	ADP
fnp-3528	273	20	a	a	DET
fnp-3528	273	21	sensitization	sensitization	NOUN
fnp-3528	273	22	of	of	ADP
fnp-3528	273	23	these	these	DET
fnp-3528	273	24	cell	cell	NOUN
fnp-3528	273	25	lines	line	NOUN
fnp-3528	273	26	toward	toward	ADP
fnp-3528	273	27	the	the	DET
fnp-3528	273	28	tkis	tkis	PROPN
fnp-3528	273	29	dasatinib	dasatinib	NOUN
fnp-3528	273	30	,	,	PUNCT
fnp-3528	273	31	imatinib	imatinib	NOUN
fnp-3528	273	32	,	,	PUNCT
fnp-3528	273	33	and	and	CCONJ
fnp-3528	273	34	nilotinib	nilotinib	NOUN
fnp-3528	273	35	when	when	SCONJ
fnp-3528	273	36	treated	treat	VERB
fnp-3528	273	37	with	with	ADP
fnp-3528	273	38	indomethacin.426	indomethacin.426	PROPN
fnp-3528	273	39	other	other	ADJ
fnp-3528	273	40	compounds	compound	NOUN
fnp-3528	273	41	were	be	AUX
fnp-3528	273	42	also	also	ADV
fnp-3528	273	43	reported	report	VERB
fnp-3528	273	44	to	to	AUX
fnp-3528	273	45	downregulate	downregulate	VERB
fnp-3528	273	46	abca3	abca3	PROPN
fnp-3528	273	47	/	/	SYM
fnp-3528	273	48	abca3	abca3	PROPN
fnp-3528	273	49	including	include	VERB
fnp-3528	273	50	the	the	DET
fnp-3528	273	51	flavonoid	flavonoid	PROPN
fnp-3528	273	52	genistein,451	genistein,451	PROPN
fnp-3528	273	53	lipopolysaccharides452	lipopolysaccharides452	PROPN
fnp-3528	273	54	–	–	PUNCT
fnp-3528	273	55	already	already	ADV
fnp-3528	273	56	demonstrated	demonstrate	VERB
fnp-3528	273	57	above	above	ADV
fnp-3528	273	58	as	as	ADP
fnp-3528	273	59	abca1	abca1	NOUN
fnp-3528	273	60	protein	protein	NOUN
fnp-3528	273	61	downregulators374	downregulators374	PROPN
fnp-3528	273	62	–	–	PUNCT
fnp-3528	273	63	and	and	CCONJ
fnp-3528	273	64	the	the	DET
fnp-3528	273	65	translocator	translocator	NOUN
fnp-3528	273	66	protein	protein	NOUN
fnp-3528	273	67	ligand	ligand	NOUN
fnp-3528	273	68	pk11195.453	pk11195.453	NOUN
fnp-3528	273	69	the	the	DET
fnp-3528	273	70	effect	effect	NOUN
fnp-3528	273	71	of	of	ADP
fnp-3528	273	72	lipopolysaccharides	lipopolysaccharide	NOUN
fnp-3528	273	73	could	could	AUX
fnp-3528	273	74	be	be	AUX
fnp-3528	273	75	abrogated	abrogate	VERB
fnp-3528	273	76	by	by	ADP
fnp-3528	273	77	ascorbic	ascorbic	NOUN
fnp-3528	273	78	acid	acid	NOUN
fnp-3528	273	79	(	(	PUNCT
fnp-3528	273	80	vitamin	vitamin	NOUN
fnp-3528	273	81	c	c	NOUN
fnp-3528	273	82	)	)	PUNCT
fnp-3528	273	83	.	.	PUNCT
fnp-3528	274	1	abca5	abca5	PROPN
fnp-3528	274	2	–	–	PUNCT
fnp-3528	274	3	abca9	abca9	NOUN
fnp-3528	274	4	interestingly	interestingly	ADV
fnp-3528	274	5	,	,	PUNCT
fnp-3528	274	6	the	the	DET
fnp-3528	274	7	abca8	abca8	NOUN
fnp-3528	274	8	inhibitor222	inhibitor222	PROPN
fnp-3528	274	9	and	and	CCONJ
fnp-3528	274	10	abca1	abca1	NOUN
fnp-3528	274	11	protein	protein	NOUN
fnp-3528	274	12	inducer253	inducer253	PROPN
fnp-3528	274	13	digoxin	digoxin	NOUN
fnp-3528	274	14	downregulated	downregulate	VERB
fnp-3528	274	15	abca5	abca5	NOUN
fnp-3528	274	16	and	and	CCONJ
fnp-3528	274	17	abca7–9	abca7–9	ADV
fnp-3528	274	18	in	in	ADP
fnp-3528	274	19	murine	murine	ADJ
fnp-3528	274	20	liver.454	liver.454	PROPN
fnp-3528	274	21	the	the	DET
fnp-3528	274	22	hmg	hmg	NOUN
fnp-3528	274	23	-	-	PUNCT
fnp-3528	274	24	coa	coa	NOUN
fnp-3528	274	25	-	-	PUNCT
fnp-3528	274	26	reductase	reductase	NOUN
fnp-3528	274	27	inhibitors	inhibitor	NOUN
fnp-3528	274	28	lovastatin	lovastatin	NOUN
fnp-3528	274	29	and	and	CCONJ
fnp-3528	274	30	mevastatin	mevastatin	NOUN
fnp-3528	274	31	downregulated	downregulate	VERB
fnp-3528	274	32	abca6	abca6	PROPN
fnp-3528	274	33	mrna	mrna	PROPN
fnp-3528	274	34	in	in	ADP
fnp-3528	274	35	human	human	ADJ
fnp-3528	274	36	umbilical	umbilical	ADJ
fnp-3528	274	37	vein	vein	ADJ
fnp-3528	274	38	endothelial	endothelial	NOUN
fnp-3528	274	39	cells.429	cells.429	ADP
fnp-3528	274	40	the	the	DET
fnp-3528	274	41	cholesterol	cholesterol	NOUN
fnp-3528	274	42	derivative	derivative	ADJ
fnp-3528	274	43	25	25	NUM
fnp-3528	274	44	-	-	PUNCT
fnp-3528	274	45	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	274	46	,	,	PUNCT
fnp-3528	274	47	which	which	PRON
fnp-3528	274	48	was	be	AUX
fnp-3528	274	49	introduced	introduce	VERB
fnp-3528	274	50	above	above	ADV
fnp-3528	274	51	as	as	SCONJ
fnp-3528	274	52	an	an	DET
fnp-3528	274	53	abca1	abca1	NOUN
fnp-3528	274	54	mrna	mrna	PROPN
fnp-3528	274	55	inducer,327	inducer,327	PROPN
fnp-3528	274	56	showed	show	VERB
fnp-3528	274	57	the	the	DET
fnp-3528	274	58	opposite	opposite	ADJ
fnp-3528	274	59	effect	effect	NOUN
fnp-3528	274	60	on	on	ADP
fnp-3528	274	61	abca7	abca7	PROPN
fnp-3528	274	62	mrna.324	mrna.324	PROPN
fnp-3528	274	63	this	this	DET
fnp-3528	274	64	finding	finding	NOUN
fnp-3528	274	65	is	be	AUX
fnp-3528	274	66	in	in	ADP
fnp-3528	274	67	agreement	agreement	NOUN
fnp-3528	274	68	with	with	ADP
fnp-3528	274	69	a	a	DET
fnp-3528	274	70	report	report	NOUN
fnp-3528	274	71	stating	state	VERB
fnp-3528	274	72	that	that	SCONJ
fnp-3528	274	73	excess	excess	ADJ
fnp-3528	274	74	cholesterol	cholesterol	NOUN
fnp-3528	274	75	reduced	reduce	VERB
fnp-3528	274	76	abca7	abca7	PROPN
fnp-3528	274	77	protein	protein	NOUN
fnp-3528	274	78	content	content	NOUN
fnp-3528	274	79	in	in	ADP
fnp-3528	274	80	both	both	CCONJ
fnp-3528	274	81	human	human	ADJ
fnp-3528	274	82	and	and	CCONJ
fnp-3528	274	83	murine	murine	ADJ
fnp-3528	274	84	fibroblasts.205	fibroblasts.205	NOUN
fnp-3528	274	85	stabilizers	stabilizer	NOUN
fnp-3528	274	86	of	of	ADP
fnp-3528	274	87	abca	abca	PROPN
fnp-3528	274	88	transporters	transporter	NOUN
fnp-3528	274	89	stabilizers	stabilizer	NOUN
fnp-3528	274	90	are	be	AUX
fnp-3528	274	91	compounds	compound	NOUN
fnp-3528	274	92	that	that	PRON
fnp-3528	274	93	promote	promote	VERB
fnp-3528	274	94	functional	functional	ADJ
fnp-3528	274	95	activity	activity	NOUN
fnp-3528	274	96	of	of	ADP
fnp-3528	274	97	abc	abc	PROPN
fnp-3528	274	98	transporters	transporter	NOUN
fnp-3528	274	99	through	through	ADP
fnp-3528	274	100	increasing	increase	VERB
fnp-3528	274	101	their	their	PRON
fnp-3528	274	102	presence	presence	NOUN
fnp-3528	274	103	at	at	ADP
fnp-3528	274	104	the	the	DET
fnp-3528	274	105	site	site	NOUN
fnp-3528	274	106	of	of	ADP
fnp-3528	274	107	action	action	NOUN
fnp-3528	274	108	(	(	PUNCT
fnp-3528	274	109	e.g.	e.g.	ADV
fnp-3528	274	110	,	,	PUNCT
fnp-3528	274	111	the	the	DET
fnp-3528	274	112	cell	cell	NOUN
fnp-3528	274	113	membrane	membrane	NOUN
fnp-3528	274	114	)	)	PUNCT
fnp-3528	274	115	either	either	CCONJ
fnp-3528	274	116	without	without	ADP
fnp-3528	274	117	interfering	interfere	VERB
fnp-3528	274	118	with	with	ADP
fnp-3528	274	119	mrna	mrna	NOUN
fnp-3528	274	120	or	or	CCONJ
fnp-3528	274	121	protein	protein	NOUN
fnp-3528	274	122	levels	level	NOUN
fnp-3528	274	123	,	,	PUNCT
fnp-3528	274	124	or	or	CCONJ
fnp-3528	274	125	in	in	ADP
fnp-3528	274	126	addition	addition	NOUN
fnp-3528	274	127	to	to	ADP
fnp-3528	274	128	these	these	DET
fnp-3528	274	129	effects	effect	NOUN
fnp-3528	274	130	.	.	PUNCT
fnp-3528	275	1	the	the	DET
fnp-3528	275	2	categorization	categorization	NOUN
fnp-3528	275	3	is	be	AUX
fnp-3528	275	4	difficult	difficult	ADJ
fnp-3528	275	5	,	,	PUNCT
fnp-3528	275	6	as	as	SCONJ
fnp-3528	275	7	the	the	DET
fnp-3528	275	8	necessary	necessary	ADJ
fnp-3528	275	9	information	information	NOUN
fnp-3528	275	10	regarding	regard	VERB
fnp-3528	275	11	many	many	ADJ
fnp-3528	275	12	modulators	modulator	NOUN
fnp-3528	275	13	of	of	ADP
fnp-3528	275	14	abca	abca	NOUN
fnp-3528	275	15	transporters	transporter	NOUN
fnp-3528	275	16	is	be	AUX
fnp-3528	275	17	lacking	lack	VERB
fnp-3528	275	18	and	and	CCONJ
fnp-3528	275	19	the	the	DET
fnp-3528	275	20	underlying	underlie	VERB
fnp-3528	275	21	mode	mode	NOUN
fnp-3528	275	22	of	of	ADP
fnp-3528	275	23	modulation	modulation	NOUN
fnp-3528	275	24	can	can	AUX
fnp-3528	275	25	not	not	PART
fnp-3528	275	26	be	be	AUX
fnp-3528	275	27	precisely	precisely	ADV
fnp-3528	275	28	identified	identify	VERB
fnp-3528	275	29	.	.	PUNCT
fnp-3528	276	1	in	in	ADP
fnp-3528	276	2	this	this	DET
fnp-3528	276	3	section	section	NOUN
fnp-3528	276	4	,	,	PUNCT
fnp-3528	276	5	we	we	PRON
fnp-3528	276	6	consider	consider	VERB
fnp-3528	276	7	only	only	ADV
fnp-3528	276	8	those	those	DET
fnp-3528	276	9	modulators	modulator	NOUN
fnp-3528	276	10	which	which	PRON
fnp-3528	276	11	predominantly	predominantly	ADV
fnp-3528	276	12	interfere	interfere	VERB
fnp-3528	276	13	with	with	ADP
fnp-3528	276	14	abca1	abca1	NOUN
fnp-3528	276	15	trafficking	trafficking	NOUN
fnp-3528	276	16	,	,	PUNCT
fnp-3528	276	17	with	with	ADP
fnp-3528	276	18	relatively	relatively	ADV
fnp-3528	276	19	minor	minor	ADJ
fnp-3528	276	20	or	or	CCONJ
fnp-3528	276	21	no	no	DET
fnp-3528	276	22	additional	additional	ADJ
fnp-3528	276	23	modes	mode	NOUN
fnp-3528	276	24	of	of	ADP
fnp-3528	276	25	action	action	NOUN
fnp-3528	276	26	/	/	SYM
fnp-3528	276	27	modulation	modulation	NOUN
fnp-3528	276	28	.	.	PUNCT
fnp-3528	277	1	stabilizers	stabilizer	NOUN
fnp-3528	277	2	are	be	AUX
fnp-3528	277	3	of	of	ADP
fnp-3528	277	4	particular	particular	ADJ
fnp-3528	277	5	interest	interest	NOUN
fnp-3528	277	6	,	,	PUNCT
fnp-3528	277	7	as	as	SCONJ
fnp-3528	277	8	they	they	PRON
fnp-3528	277	9	may	may	AUX
fnp-3528	277	10	represent	represent	VERB
fnp-3528	277	11	a	a	DET
fnp-3528	277	12	novel	novel	ADJ
fnp-3528	277	13	generation	generation	NOUN
fnp-3528	277	14	of	of	ADP
fnp-3528	277	15	functional	functional	ADJ
fnp-3528	277	16	abc	abc	PROPN
fnp-3528	277	17	transporter	transporter	NOUN
fnp-3528	277	18	activators	activator	NOUN
fnp-3528	277	19	,	,	PUNCT
fnp-3528	277	20	expanding	expand	VERB
fnp-3528	277	21	treatment	treatment	NOUN
fnp-3528	277	22	options	option	NOUN
fnp-3528	277	23	for	for	ADP
fnp-3528	277	24	several	several	ADJ
fnp-3528	277	25	diseases	disease	NOUN
fnp-3528	277	26	,	,	PUNCT
fnp-3528	277	27	particularly	particularly	ADV
fnp-3528	277	28	ad	ad	NOUN
fnp-3528	277	29	.	.	PUNCT
fnp-3528	278	1	abca1	abca1	PROPN
fnp-3528	278	2	probucol	probucol	PROPN
fnp-3528	278	3	and	and	CCONJ
fnp-3528	278	4	cyclosporine	cyclosporine	VERB
fnp-3528	278	5	a	a	PRON
fnp-3528	278	6	were	be	AUX
fnp-3528	278	7	demonstrated	demonstrate	VERB
fnp-3528	278	8	above	above	ADV
fnp-3528	278	9	to	to	PART
fnp-3528	278	10	decrease	decrease	VERB
fnp-3528	278	11	abca1	abca1	NOUN
fnp-3528	278	12	turnover	turnover	NOUN
fnp-3528	278	13	and	and	CCONJ
fnp-3528	278	14	increasing	increase	VERB
fnp-3528	278	15	abca1	abca1	NOUN
fnp-3528	278	16	protein	protein	NOUN
fnp-3528	278	17	content	content	NOUN
fnp-3528	278	18	at	at	ADP
fnp-3528	278	19	the	the	DET
fnp-3528	278	20	cell	cell	NOUN
fnp-3528	278	21	membrane.246,275	membrane.246,275	PROPN
fnp-3528	278	22	arakawa	arakawa	PROPN
fnp-3528	278	23	et	et	PROPN
fnp-3528	278	24	al	al	PROPN
fnp-3528	278	25	.	.	PROPN
fnp-3528	278	26	demonstrated	demonstrate	VERB
fnp-3528	278	27	that	that	SCONJ
fnp-3528	278	28	the	the	DET
fnp-3528	278	29	probucol	probucol	PROPN
fnp-3528	278	30	metabolites	metabolite	NOUN
fnp-3528	278	31	spiroquinone	spiroquinone	NOUN
fnp-3528	278	32	and	and	CCONJ
fnp-3528	278	33	diphenoquinone	diphenoquinone	NOUN
fnp-3528	278	34	did	do	AUX
fnp-3528	278	35	not	not	PART
fnp-3528	278	36	inhibit	inhibit	VERB
fnp-3528	278	37	abca1	abca1	NOUN
fnp-3528	278	38	-	-	PUNCT
fnp-3528	278	39	mediated	mediate	VERB
fnp-3528	278	40	transport	transport	NOUN
fnp-3528	278	41	like	like	ADP
fnp-3528	278	42	their	their	PRON
fnp-3528	278	43	parent	parent	NOUN
fnp-3528	278	44	compound	compound	NOUN
fnp-3528	278	45	but	but	CCONJ
fnp-3528	278	46	rather	rather	ADV
fnp-3528	278	47	increased	increase	VERB
fnp-3528	278	48	the	the	DET
fnp-3528	278	49	fraction	fraction	NOUN
fnp-3528	278	50	of	of	ADP
fnp-3528	278	51	functional	functional	ADJ
fnp-3528	278	52	abca1	abca1	NOUN
fnp-3528	278	53	in	in	ADP
fnp-3528	278	54	the	the	DET
fnp-3528	278	55	cell	cell	NOUN
fnp-3528	278	56	membrane.275	membrane.275	PROPN
fnp-3528	278	57	this	this	DET
fnp-3528	278	58	stabilization	stabilization	NOUN
fnp-3528	278	59	led	lead	VERB
fnp-3528	278	60	to	to	ADP
fnp-3528	278	61	increased	increase	VERB
fnp-3528	278	62	cholesterol	cholesterol	NOUN
fnp-3528	278	63	and	and	CCONJ
fnp-3528	278	64	phospholipid	phospholipid	NOUN
fnp-3528	278	65	efflux	efflux	NOUN
fnp-3528	278	66	.	.	PUNCT
fnp-3528	279	1	both	both	DET
fnp-3528	279	2	effects	effect	NOUN
fnp-3528	279	3	were	be	AUX
fnp-3528	279	4	observed	observe	VERB
fnp-3528	279	5	at	at	ADP
fnp-3528	279	6	very	very	ADV
fnp-3528	279	7	low	low	ADJ
fnp-3528	279	8	nanomolar	nanomolar	ADJ
fnp-3528	279	9	concentrations,275	concentrations,275	NOUN
fnp-3528	279	10	while	while	SCONJ
fnp-3528	279	11	abca1	abca1	PROPN
fnp-3528	279	12	mrna	mrna	PROPN
fnp-3528	279	13	remained	remain	VERB
fnp-3528	279	14	stable.275	stable.275	ADV
fnp-3528	279	15	strikingly	strikingly	ADV
fnp-3528	279	16	,	,	PUNCT
fnp-3528	279	17	spiroquinone	spiroquinone	NOUN
fnp-3528	279	18	and	and	CCONJ
fnp-3528	279	19	diphenoquinone	diphenoquinone	NOUN
fnp-3528	279	20	decreased	decrease	VERB
fnp-3528	279	21	vascular	vascular	ADJ
fnp-3528	279	22	lipid	lipid	NOUN
fnp-3528	279	23	deposits	deposit	NOUN
fnp-3528	279	24	in	in	ADP
fnp-3528	279	25	vivo	vivo	NOUN
fnp-3528	279	26	in	in	ADP
fnp-3528	279	27	cholesterol	cholesterol	NOUN
fnp-3528	279	28	-	-	PUNCT
fnp-3528	279	29	fed	feed	VERB
fnp-3528	279	30	rabbits,275	rabbits,275	PROPN
fnp-3528	279	31	which	which	PRON
fnp-3528	279	32	may	may	AUX
fnp-3528	279	33	be	be	AUX
fnp-3528	279	34	of	of	ADP
fnp-3528	279	35	relevance	relevance	NOUN
fnp-3528	279	36	for	for	ADP
fnp-3528	279	37	ad	ad	NOUN
fnp-3528	279	38	and	and	CCONJ
fnp-3528	279	39	potentially	potentially	ADV
fnp-3528	279	40	other	other	ADJ
fnp-3528	279	41	neurodegenerative	neurodegenerative	ADJ
fnp-3528	279	42	diseases	disease	NOUN
fnp-3528	279	43	.	.	PUNCT
fnp-3528	280	1	a	a	DET
fnp-3528	280	2	similar	similar	ADJ
fnp-3528	280	3	mode	mode	NOUN
fnp-3528	280	4	of	of	ADP
fnp-3528	280	5	stabilization	stabilization	NOUN
fnp-3528	280	6	,	,	PUNCT
fnp-3528	280	7	albeit	albeit	SCONJ
fnp-3528	280	8	with	with	ADP
fnp-3528	280	9	less	less	ADJ
fnp-3528	280	10	potency	potency	NOUN
fnp-3528	280	11	and	and	CCONJ
fnp-3528	280	12	no	no	NOUN
fnp-3528	280	13	in	in	ADP
fnp-3528	280	14	vivo	vivo	ADJ
fnp-3528	280	15	confirmation	confirmation	NOUN
fnp-3528	280	16	,	,	PUNCT
fnp-3528	280	17	has	have	AUX
fnp-3528	280	18	been	be	AUX
fnp-3528	280	19	observed	observe	VERB
fnp-3528	280	20	for	for	ADP
fnp-3528	280	21	the	the	DET
fnp-3528	280	22	flavonoid	flavonoid	PROPN
fnp-3528	280	23	wogonin,254	wogonin,254	PROPN
fnp-3528	280	24	the	the	DET
fnp-3528	280	25	olive	olive	ADJ
fnp-3528	280	26	oil	oil	NOUN
fnp-3528	280	27	-	-	PUNCT
fnp-3528	280	28	derived	derive	VERB
fnp-3528	280	29	compound	compound	NOUN
fnp-3528	280	30	erythrodiol,395	erythrodiol,395	PROPN
fnp-3528	280	31	and	and	CCONJ
fnp-3528	280	32	certain	certain	ADJ
fnp-3528	280	33	thiol	thiol	ADJ
fnp-3528	280	34	proteinase	proteinase	NOUN
fnp-3528	280	35	inhibitors	inhibitor	NOUN
fnp-3528	280	36	,	,	PUNCT
fnp-3528	280	37	in	in	ADP
fnp-3528	280	38	particular	particular	ADJ
fnp-3528	280	39	n	n	CCONJ
fnp-3528	280	40	-	-	PUNCT
fnp-3528	280	41	acetyl	acetyl	NOUN
fnp-3528	280	42	-	-	PUNCT
fnp-3528	280	43	leu	leu	PROPN
fnp-3528	280	44	-	-	PUNCT
fnp-3528	280	45	leu	leu	PROPN
fnp-3528	280	46	-	-	PROPN
fnp-3528	280	47	norleucinal	norleucinal	ADJ
fnp-3528	280	48	and	and	CCONJ
fnp-3528	280	49	leupeptin.316,386	leupeptin.316,386	NOUN
fnp-3528	280	50	finally	finally	ADV
fnp-3528	280	51	,	,	PUNCT
fnp-3528	280	52	the	the	DET
fnp-3528	280	53	abca1	abca1	NOUN
fnp-3528	280	54	mrna	mrna	PROPN
fnp-3528	280	55	and	and	CCONJ
fnp-3528	280	56	abca1	abca1	NOUN
fnp-3528	280	57	protein	protein	NOUN
fnp-3528	280	58	inducer	inducer	NOUN
fnp-3528	280	59	testosterone	testosterone	NOUN
fnp-3528	280	60	was	be	AUX
fnp-3528	280	61	demonstrated	demonstrate	VERB
fnp-3528	280	62	to	to	PART
fnp-3528	280	63	promote	promote	VERB
fnp-3528	280	64	abca1	abca1	NOUN
fnp-3528	280	65	trafficking	trafficking	NOUN
fnp-3528	280	66	to	to	ADP
fnp-3528	280	67	the	the	DET
fnp-3528	280	68	cell	cell	NOUN
fnp-3528	281	1	membrane.357	membrane.357	VERB
fnp-3528	281	2	other	other	ADJ
fnp-3528	281	3	abca	abca	NOUN
fnp-3528	281	4	transporters	transporter	NOUN
fnp-3528	281	5	the	the	DET
fnp-3528	281	6	cystic	cystic	ADJ
fnp-3528	281	7	fibrosis	fibrosis	NOUN
fnp-3528	281	8	transmembrane	transmembrane	NOUN
fnp-3528	281	9	conductance	conductance	NOUN
fnp-3528	281	10	regulator	regulator	NOUN
fnp-3528	281	11	(	(	PUNCT
fnp-3528	281	12	cftr	cftr	NOUN
fnp-3528	281	13	;	;	PUNCT
fnp-3528	281	14	abcc7	abcc7	NOUN
fnp-3528	281	15	)	)	PUNCT
fnp-3528	281	16	correctors	corrector	NOUN
fnp-3528	281	17	c13,455	c13,455	VERB
fnp-3528	282	1	c14,455	c14,455	INTJ
fnp-3528	282	2	c17,455	c17,455	PROPN
fnp-3528	282	3	genistein,456	genistein,456	PROPN
fnp-3528	282	4	and	and	CCONJ
fnp-3528	282	5	ivacaftor	ivacaftor	NOUN
fnp-3528	282	6	(	(	PUNCT
fnp-3528	282	7	figure	figure	NOUN
fnp-3528	282	8	 	 	SPACE
fnp-3528	282	9	2)456	2)456	NOUN
fnp-3528	282	10	were	be	AUX
fnp-3528	282	11	demonstrated	demonstrate	VERB
fnp-3528	282	12	to	to	PART
fnp-3528	282	13	rescue	rescue	VERB
fnp-3528	282	14	abca3	abca3	NOUN
fnp-3528	282	15	mutants	mutant	NOUN
fnp-3528	282	16	by	by	ADP
fnp-3528	282	17	increasing	increase	VERB
fnp-3528	282	18	total	total	ADJ
fnp-3528	282	19	abca3	abca3	NOUN
fnp-3528	282	20	mutant	mutant	ADJ
fnp-3528	282	21	protein	protein	NOUN
fnp-3528	282	22	levels,455	levels,455	ADP
fnp-3528	282	23	promoting	promote	VERB
fnp-3528	282	24	subcellular	subcellular	ADJ
fnp-3528	282	25	targeting	targeting	NOUN
fnp-3528	282	26	of	of	ADP
fnp-3528	282	27	abca3	abca3	PROPN
fnp-3528	282	28	into	into	ADP
fnp-3528	282	29	vesicular	vesicular	ADJ
fnp-3528	282	30	bodies,455	bodies,455	ADV
fnp-3528	282	31	and	and	CCONJ
fnp-3528	282	32	improving	improve	VERB
fnp-3528	282	33	lipid	lipid	NOUN
fnp-3528	282	34	transport	transport	NOUN
fnp-3528	282	35	function	function	NOUN
fnp-3528	282	36	of	of	ADP
fnp-3528	282	37	abca3.456	abca3.456	NOUN
fnp-3528	282	38	furthermore	furthermore	ADV
fnp-3528	282	39	,	,	PUNCT
fnp-3528	282	40	the	the	DET
fnp-3528	282	41	correctors	corrector	NOUN
fnp-3528	282	42	lumacaftor	lumacaftor	NOUN
fnp-3528	282	43	(	(	PUNCT
fnp-3528	282	44	vx-809	vx-809	NOUN
fnp-3528	282	45	;	;	PUNCT
fnp-3528	282	46	figure	figure	NOUN
fnp-3528	282	47	 	 	SPACE
fnp-3528	282	48	2	2	NUM
fnp-3528	282	49	)	)	PUNCT
fnp-3528	282	50	,	,	PUNCT
fnp-3528	282	51	c3	c3	NOUN
fnp-3528	282	52	,	,	PUNCT
fnp-3528	282	53	and	and	CCONJ
fnp-3528	282	54	c4	c4	NOUN
fnp-3528	282	55	,	,	PUNCT
fnp-3528	282	56	and	and	CCONJ
fnp-3528	282	57	c18	c18	NOUN
fnp-3528	282	58	increased	increase	VERB
fnp-3528	282	59	the	the	DET
fnp-3528	282	60	presence	presence	NOUN
fnp-3528	282	61	of	of	ADP
fnp-3528	282	62	abca4	abca4	PROPN
fnp-3528	282	63	at	at	ADP
fnp-3528	282	64	the	the	DET
fnp-3528	282	65	cell	cell	NOUN
fnp-3528	282	66	membrane	membrane	NOUN
fnp-3528	282	67	in	in	ADP
fnp-3528	282	68	abca4	abca4	ADJ
fnp-3528	282	69	-	-	PUNCT
fnp-3528	282	70	overexpressing	overexpresse	VERB
fnp-3528	282	71	hek293	hek293	PROPN
fnp-3528	282	72	cells	cell	NOUN
fnp-3528	282	73	,	,	PUNCT
fnp-3528	282	74	indicating	indicate	VERB
fnp-3528	282	75	promotion	promotion	NOUN
fnp-3528	282	76	of	of	ADP
fnp-3528	282	77	abca4	abca4	PROPN
fnp-3528	282	78	trafficking	traffic	VERB
fnp-3528	282	79	to	to	ADP
fnp-3528	282	80	the	the	DET
fnp-3528	282	81	plasma	plasma	NOUN
fnp-3528	282	82	membrane.457,458	membrane.457,458	PROPN
fnp-3528	282	83	promotion	promotion	NOUN
fnp-3528	282	84	of	of	ADP
fnp-3528	282	85	trafficking	trafficking	NOUN
fnp-3528	282	86	has	have	AUX
fnp-3528	282	87	already	already	ADV
fnp-3528	282	88	been	be	AUX
fnp-3528	282	89	demonstrated	demonstrate	VERB
fnp-3528	282	90	for	for	ADP
fnp-3528	282	91	other	other	ADJ
fnp-3528	282	92	abc	abc	PROPN
fnp-3528	282	93	transporters	transporter	NOUN
fnp-3528	282	94	,	,	PUNCT
fnp-3528	282	95	such	such	ADJ
fnp-3528	282	96	as	as	ADP
fnp-3528	282	97	abcc123,24	abcc123,24	NOUN
fnp-3528	282	98	and	and	CCONJ
fnp-3528	282	99	abcc7.459	abcc7.459	NOUN
fnp-3528	282	100	hence	hence	ADV
fnp-3528	282	101	,	,	PUNCT
fnp-3528	282	102	this	this	DET
fnp-3528	282	103	mechanism	mechanism	NOUN
fnp-3528	282	104	represents	represent	VERB
fnp-3528	282	105	a	a	DET
fnp-3528	282	106	new	new	ADJ
fnp-3528	282	107	potential	potential	ADJ
fnp-3528	282	108	therapeutic	therapeutic	ADJ
fnp-3528	282	109	option	option	NOUN
fnp-3528	282	110	for	for	ADP
fnp-3528	282	111	abca	abca	ADJ
fnp-3528	282	112	transporter	transporter	NOUN
fnp-3528	282	113	-	-	PUNCT
fnp-3528	282	114	related	relate	VERB
fnp-3528	282	115	ad	ad	NOUN
fnp-3528	282	116	.	.	PUNCT
fnp-3528	283	1	as	as	SCONJ
fnp-3528	283	2	proposed	propose	VERB
fnp-3528	283	3	for	for	ADP
fnp-3528	283	4	abcc7,460	abcc7,460	PROPN
fnp-3528	283	5	the	the	DET
fnp-3528	283	6	authors	author	NOUN
fnp-3528	283	7	suggested	suggest	VERB
fnp-3528	283	8	a	a	DET
fnp-3528	283	9	direct	direct	ADJ
fnp-3528	283	10	binding	binding	NOUN
fnp-3528	283	11	of	of	ADP
fnp-3528	283	12	the	the	DET
fnp-3528	283	13	correctors	corrector	NOUN
fnp-3528	283	14	to	to	ADP
fnp-3528	283	15	the	the	DET
fnp-3528	283	16	abca4	abca4	ADJ
fnp-3528	283	17	protein,457	protein,457	NOUN
fnp-3528	283	18	which	which	PRON
fnp-3528	283	19	has	have	AUX
fnp-3528	283	20	not	not	PART
fnp-3528	283	21	yet	yet	ADV
fnp-3528	283	22	been	be	AUX
fnp-3528	283	23	proven	prove	VERB
fnp-3528	283	24	.	.	PUNCT
fnp-3528	284	1	in	in	ADP
fnp-3528	284	2	an	an	DET
fnp-3528	284	3	abca12	abca12	NOUN
fnp-3528	284	4	pig	pig	NOUN
fnp-3528	284	5	model	model	NOUN
fnp-3528	284	6	of	of	ADP
fnp-3528	284	7	harlequin	harlequin	PROPN
fnp-3528	284	8	ichthyosis	ichthyosis	NOUN
fnp-3528	284	9	,	,	PUNCT
fnp-3528	284	10	acitretin	acitretin	NOUN
fnp-3528	284	11	(	(	PUNCT
fnp-3528	284	12	figure	figure	NOUN
fnp-3528	284	13	 	 	SPACE
fnp-3528	284	14	2	2	NUM
fnp-3528	284	15	)	)	PUNCT
fnp-3528	284	16	treatment	treatment	NOUN
fnp-3528	284	17	resulted	result	VERB
fnp-3528	284	18	in	in	ADP
fnp-3528	284	19	a	a	DET
fnp-3528	284	20	redistribution	redistribution	NOUN
fnp-3528	284	21	of	of	ADP
fnp-3528	284	22	abca12	abca12	NOUN
fnp-3528	284	23	in	in	ADP
fnp-3528	284	24	the	the	DET
fnp-3528	284	25	skin	skin	NOUN
fnp-3528	284	26	compared	compare	VERB
fnp-3528	284	27	to	to	ADP
fnp-3528	284	28	wild	wild	ADJ
fnp-3528	284	29	-	-	PUNCT
fnp-3528	284	30	type	type	NOUN
fnp-3528	284	31	pigs	pig	NOUN
fnp-3528	284	32	,	,	PUNCT
fnp-3528	284	33	and	and	CCONJ
fnp-3528	284	34	thus	thus	ADV
fnp-3528	284	35	,	,	PUNCT
fnp-3528	284	36	a	a	DET
fnp-3528	284	37	higher	high	ADJ
fnp-3528	284	38	survival	survival	NOUN
fnp-3528	284	39	rate.430	rate.430	NOUN
fnp-3528	284	40	destabilizers	destabilizer	NOUN
fnp-3528	284	41	of	of	ADP
fnp-3528	284	42	abca	abca	PROPN
fnp-3528	284	43	transporters	transporter	NOUN
fnp-3528	284	44	natural	natural	ADJ
fnp-3528	284	45	compounds	compound	NOUN
fnp-3528	284	46	in	in	ADP
fnp-3528	284	47	contrast	contrast	NOUN
fnp-3528	284	48	to	to	ADP
fnp-3528	284	49	compounds	compound	NOUN
fnp-3528	284	50	that	that	PRON
fnp-3528	284	51	promote	promote	VERB
fnp-3528	284	52	trafficking	trafficking	NOUN
fnp-3528	284	53	of	of	ADP
fnp-3528	284	54	functional	functional	ADJ
fnp-3528	284	55	abca1	abca1	NOUN
fnp-3528	284	56	to	to	ADP
fnp-3528	284	57	the	the	DET
fnp-3528	284	58	plasma	plasma	NOUN
fnp-3528	284	59	membrane	membrane	NOUN
fnp-3528	284	60	,	,	PUNCT
fnp-3528	284	61	other	other	ADJ
fnp-3528	284	62	compounds	compound	NOUN
fnp-3528	284	63	that	that	PRON
fnp-3528	284	64	have	have	VERB
fnp-3528	284	65	the	the	DET
fnp-3528	284	66	opposite	opposite	ADJ
fnp-3528	284	67	effect	effect	NOUN
fnp-3528	284	68	have	have	AUX
fnp-3528	284	69	been	be	AUX
fnp-3528	284	70	named	name	VERB
fnp-3528	284	71	‘	'	PUNCT
fnp-3528	284	72	destablizers	destablizer	NOUN
fnp-3528	284	73	’	'	PUNCT
fnp-3528	284	74	.	.	PUNCT
fnp-3528	285	1	so	so	ADV
fnp-3528	285	2	far	far	ADV
fnp-3528	285	3	,	,	PUNCT
fnp-3528	285	4	only	only	ADV
fnp-3528	285	5	agents	agent	NOUN
fnp-3528	285	6	targeting	target	VERB
fnp-3528	285	7	abca1	abca1	NOUN
fnp-3528	285	8	are	be	AUX
fnp-3528	285	9	known	know	VERB
fnp-3528	285	10	.	.	PUNCT
fnp-3528	286	1	the	the	DET
fnp-3528	286	2	lactone	lactone	PROPN
fnp-3528	286	3	antibiotic	antibiotic	PROPN
fnp-3528	286	4	brefeldin	brefeldin	VERB
fnp-3528	286	5	a	a	DET
fnp-3528	286	6	(	(	PUNCT
fnp-3528	286	7	figure	figure	NOUN
fnp-3528	286	8	 	 	SPACE
fnp-3528	286	9	2	2	NUM
fnp-3528	286	10	)	)	PUNCT
fnp-3528	286	11	interfered	interfere	VERB
fnp-3528	286	12	with	with	ADP
fnp-3528	286	13	abca1	abca1	NOUN
fnp-3528	286	14	cell	cell	NOUN
fnp-3528	286	15	-	-	PUNCT
fnp-3528	286	16	surface	surface	NOUN
fnp-3528	286	17	localization	localization	NOUN
fnp-3528	286	18	,	,	PUNCT
fnp-3528	286	19	recycling	recycling	NOUN
fnp-3528	286	20	,	,	PUNCT
fnp-3528	286	21	and	and	CCONJ
fnp-3528	286	22	intracellular	intracellular	ADJ
fnp-3528	286	23	trafficking.387,461	trafficking.387,461	NOUN
fnp-3528	286	24	-	-	SYM
fnp-3528	286	25	463	463	NUM
fnp-3528	286	26	these	these	DET
fnp-3528	286	27	effects	effect	NOUN
fnp-3528	286	28	were	be	AUX
fnp-3528	286	29	at	at	ADP
fnp-3528	286	30	least	least	ADJ
fnp-3528	286	31	in	in	ADP
fnp-3528	286	32	part	part	NOUN
fnp-3528	286	33	dependent	dependent	ADJ
fnp-3528	286	34	on	on	ADP
fnp-3528	286	35	the	the	DET
fnp-3528	286	36	interaction	interaction	NOUN
fnp-3528	286	37	with	with	ADP
fnp-3528	286	38	brefeldin	brefeldin	VERB
fnp-3528	286	39	1	1	NUM
fnp-3528	286	40	-	-	PUNCT
fnp-3528	286	41	inhibited	inhibit	VERB
fnp-3528	286	42	guanine	guanine	NOUN
fnp-3528	286	43	nucleotide	nucleotide	NOUN
fnp-3528	286	44	exchange	exchange	NOUN
fnp-3528	286	45	protein	protein	NOUN
fnp-3528	286	46	(	(	PUNCT
fnp-3528	286	47	big1).461	big1).461	VERB
fnp-3528	286	48	this	this	DET
fnp-3528	286	49	interference	interference	NOUN
fnp-3528	286	50	reduced	reduce	VERB
fnp-3528	286	51	the	the	DET
fnp-3528	286	52	functional	functional	ADJ
fnp-3528	286	53	fraction	fraction	NOUN
fnp-3528	286	54	of	of	ADP
fnp-3528	286	55	abca1	abca1	PROPN
fnp-3528	286	56	and	and	CCONJ
fnp-3528	286	57	,	,	PUNCT
fnp-3528	286	58	consequently	consequently	ADV
fnp-3528	286	59	,	,	PUNCT
fnp-3528	286	60	abca1	abca1	NOUN
fnp-3528	286	61	-	-	PUNCT
fnp-3528	286	62	mediated	mediate	VERB
fnp-3528	286	63	cholesterol	cholesterol	NOUN
fnp-3528	286	64	and	and	CCONJ
fnp-3528	286	65	phospholipid	phospholipid	NOUN
fnp-3528	286	66	transport.255	transport.255	VERB
fnp-3528	286	67	similar	similar	ADJ
fnp-3528	286	68	observations	observation	NOUN
fnp-3528	286	69	have	have	AUX
fnp-3528	286	70	been	be	AUX
fnp-3528	286	71	made	make	VERB
fnp-3528	286	72	for	for	ADP
fnp-3528	286	73	the	the	DET
fnp-3528	286	74	polyether	polyether	NOUN
fnp-3528	286	75	-	-	PUNCT
fnp-3528	286	76	antibiotics	antibiotic	NOUN
fnp-3528	286	77	monensin	monensin	NOUN
fnp-3528	286	78	,	,	PUNCT
fnp-3528	286	79	which	which	PRON
fnp-3528	286	80	reduced	reduce	VERB
fnp-3528	286	81	abca1	abca1	NOUN
fnp-3528	286	82	turnover	turnover	NOUN
fnp-3528	286	83	and	and	CCONJ
fnp-3528	286	84	trapped	trap	VERB
fnp-3528	286	85	it	it	PRON
fnp-3528	286	86	inside	inside	ADP
fnp-3528	286	87	endoand	endoand	PROPN
fnp-3528	286	88	lysosomes	lysosomes	PROPN
fnp-3528	286	89	.	.	PUNCT
fnp-3528	287	1	subsequently	subsequently	ADV
fnp-3528	287	2	,	,	PUNCT
fnp-3528	287	3	monensin	monensin	PROPN
fnp-3528	287	4	reduced	reduce	VERB
fnp-3528	287	5	the	the	DET
fnp-3528	287	6	functional	functional	ADJ
fnp-3528	287	7	presence	presence	NOUN
fnp-3528	287	8	of	of	ADP
fnp-3528	287	9	abca1	abca1	NOUN
fnp-3528	287	10	at	at	ADP
fnp-3528	287	11	the	the	DET
fnp-3528	287	12	cell	cell	NOUN
fnp-3528	287	13	surface,464	surface,464	ADP
fnp-3528	287	14	lowered	lower	VERB
fnp-3528	287	15	cholesterol	cholesterol	NOUN
fnp-3528	287	16	efflux,463	efflux,463	PROPN
fnp-3528	287	17	and	and	CCONJ
fnp-3528	287	18	increased	increase	VERB
fnp-3528	287	19	intracellular	intracellular	ADJ
fnp-3528	287	20	cholesterol	cholesterol	NOUN
fnp-3528	287	21	content.463,464	content.463,464	NOUN
fnp-3528	287	22	the	the	DET
fnp-3528	287	23	same	same	ADJ
fnp-3528	287	24	was	be	AUX
fnp-3528	287	25	demonstrated	demonstrate	VERB
fnp-3528	287	26	for	for	ADP
fnp-3528	287	27	nigericin	nigericin	NOUN
fnp-3528	287	28	,	,	PUNCT
fnp-3528	287	29	another	another	DET
fnp-3528	287	30	polyether	polyether	NOUN
fnp-3528	287	31	-	-	PUNCT
fnp-3528	287	32	antibiotic	antibiotic	ADJ
fnp-3528	287	33	,	,	PUNCT
fnp-3528	287	34	which	which	PRON
fnp-3528	287	35	increased	increase	VERB
fnp-3528	287	36	intracellular	intracellular	ADJ
fnp-3528	287	37	cholesterol	cholesterol	NOUN
fnp-3528	287	38	concentration,463	concentration,463	PROPN
fnp-3528	287	39	and	and	CCONJ
fnp-3528	287	40	inhibited	inhibited	ADJ
fnp-3528	287	41	abca1	abca1	NOUN
fnp-3528	287	42	-	-	PUNCT
fnp-3528	287	43	mediated	mediate	VERB
fnp-3528	287	44	cholesterol	cholesterol	NOUN
fnp-3528	287	45	efflux	efflux	VERB
fnp-3528	287	46	from	from	ADP
fnp-3528	287	47	raw264.7	raw264.7	PROPN
fnp-3528	287	48	macrophages.385	macrophages.385	ADJ
fnp-3528	287	49	inhibition	inhibition	NOUN
fnp-3528	287	50	of	of	ADP
fnp-3528	287	51	intracellular	intracellular	ADJ
fnp-3528	287	52	organelle	organelle	NOUN
fnp-3528	287	53	transport	transport	NOUN
fnp-3528	287	54	as	as	SCONJ
fnp-3528	287	55	suggested	suggest	VERB
fnp-3528	287	56	for	for	ADP
fnp-3528	287	57	brefeldin	brefeldin	VERB
fnp-3528	287	58	a387,461	a387,461	NOUN
fnp-3528	287	59	-	-	ADJ
fnp-3528	287	60	463	463	NUM
fnp-3528	287	61	and	and	CCONJ
fnp-3528	287	62	monensin463,464	monensin463,464	NOUN
fnp-3528	287	63	likely	likely	ADV
fnp-3528	287	64	applies	apply	VERB
fnp-3528	287	65	to	to	ADP
fnp-3528	287	66	nigericin	nigericin	PROPN
fnp-3528	287	67	as	as	ADP
fnp-3528	287	68	well.463,465	well.463,465	NOUN
fnp-3528	287	69	in	in	ADP
fnp-3528	287	70	addition	addition	NOUN
fnp-3528	287	71	,	,	PUNCT
fnp-3528	287	72	the	the	DET
fnp-3528	287	73	endoplasmic	endoplasmic	ADJ
fnp-3528	287	74	reticulum	reticulum	NOUN
fnp-3528	287	75	stress	stress	NOUN
fnp-3528	287	76	promotor	promotor	NOUN
fnp-3528	287	77	,	,	PUNCT
fnp-3528	287	78	tunicamycin	tunicamycin	PROPN
fnp-3528	287	79	,	,	PUNCT
fnp-3528	287	80	also	also	ADV
fnp-3528	287	81	reduced	reduce	VERB
fnp-3528	287	82	abca1	abca1	NOUN
fnp-3528	287	83	protein	protein	NOUN
fnp-3528	287	84	levels.360,466	levels.360,466	PROPN
fnp-3528	287	85	this	this	DET
fnp-3528	287	86	‘	'	PUNCT
fnp-3528	287	87	downregulation	downregulation	NOUN
fnp-3528	287	88	’	'	PUNCT
fnp-3528	287	89	is	be	AUX
fnp-3528	287	90	most	most	ADV
fnp-3528	287	91	likely	likely	ADV
fnp-3528	287	92	mediated	mediate	VERB
fnp-3528	287	93	though	though	SCONJ
fnp-3528	287	94	stress	stress	NOUN
fnp-3528	287	95	-	-	PUNCT
fnp-3528	287	96	induced	induce	VERB
fnp-3528	287	97	impaired	impaired	ADJ
fnp-3528	287	98	abca1	abca1	NOUN
fnp-3528	287	99	trafficking	trafficking	NOUN
fnp-3528	287	100	and/or	and/or	CCONJ
fnp-3528	287	101	increased	increase	VERB
fnp-3528	287	102	abca1	abca1	NOUN
fnp-3528	287	103	degradation.466	degradation.466	NUM
fnp-3528	287	104	however	however	ADV
fnp-3528	287	105	,	,	PUNCT
fnp-3528	287	106	in	in	ADP
fnp-3528	287	107	terms	term	NOUN
fnp-3528	287	108	of	of	ADP
fnp-3528	287	109	selective	selective	ADJ
fnp-3528	287	110	targeting	targeting	NOUN
fnp-3528	287	111	of	of	ADP
fnp-3528	287	112	abca1	abca1	NOUN
fnp-3528	287	113	in	in	ADP
fnp-3528	287	114	particular	particular	ADJ
fnp-3528	287	115	,	,	PUNCT
fnp-3528	287	116	or	or	CCONJ
fnp-3528	287	117	abca	abca	NOUN
fnp-3528	287	118	transporters	transporter	NOUN
fnp-3528	287	119	in	in	ADP
fnp-3528	287	120	general	general	ADJ
fnp-3528	287	121	,	,	PUNCT
fnp-3528	287	122	these	these	DET
fnp-3528	287	123	agents	agent	NOUN
fnp-3528	287	124	are	be	AUX
fnp-3528	287	125	less	less	ADV
fnp-3528	287	126	suitable	suitable	ADJ
fnp-3528	287	127	as	as	ADP
fnp-3528	287	128	in	in	ADP
fnp-3528	287	129	vivo	vivo	ADJ
fnp-3528	287	130	agents	agent	NOUN
fnp-3528	287	131	and	and	CCONJ
fnp-3528	287	132	serve	serve	VERB
fnp-3528	287	133	better	well	ADV
fnp-3528	287	134	as	as	ADP
fnp-3528	287	135	in	in	ADP
fnp-3528	287	136	vitro	vitro	X
fnp-3528	287	137	controls	control	NOUN
fnp-3528	287	138	.	.	PUNCT
fnp-3528	288	1	the	the	DET
fnp-3528	288	2	palmitic	palmitic	ADJ
fnp-3528	288	3	acid	acid	NOUN
fnp-3528	288	4	derivative	derivative	ADJ
fnp-3528	288	5	2	2	NUM
fnp-3528	288	6	-	-	PUNCT
fnp-3528	288	7	bromopalmitate	bromopalmitate	NOUN
fnp-3528	288	8	(	(	PUNCT
fnp-3528	288	9	figure	figure	NOUN
fnp-3528	288	10	 	 	SPACE
fnp-3528	288	11	2	2	NUM
fnp-3528	288	12	)	)	PUNCT
fnp-3528	288	13	inhibited	inhibited	ADJ
fnp-3528	288	14	trafficking	trafficking	NOUN
fnp-3528	288	15	of	of	ADP
fnp-3528	288	16	abca1	abca1	NOUN
fnp-3528	288	17	to	to	ADP
fnp-3528	288	18	the	the	DET
fnp-3528	288	19	plasma	plasma	NOUN
fnp-3528	288	20	membrane	membrane	NOUN
fnp-3528	288	21	and	and	CCONJ
fnp-3528	288	22	reduced	reduced	ADJ
fnp-3528	288	23	abca1	abca1	NOUN
fnp-3528	288	24	-	-	PUNCT
fnp-3528	288	25	mediated	mediate	VERB
fnp-3528	288	26	cholesterol	cholesterol	NOUN
fnp-3528	288	27	efflux.273,467	efflux.273,467	PROPN
fnp-3528	288	28	however	however	ADV
fnp-3528	288	29	,	,	PUNCT
fnp-3528	288	30	the	the	DET
fnp-3528	288	31	observed	observed	ADJ
fnp-3528	288	32	effect	effect	NOUN
fnp-3528	288	33	that	that	SCONJ
fnp-3528	288	34	abca1	abca1	NOUN
fnp-3528	288	35	did	do	AUX
fnp-3528	288	36	not	not	PART
fnp-3528	288	37	translocate	translocate	VERB
fnp-3528	288	38	to	to	ADP
fnp-3528	288	39	the	the	DET
fnp-3528	288	40	cell	cell	NOUN
fnp-3528	288	41	membrane	membrane	NOUN
fnp-3528	288	42	in	in	ADP
fnp-3528	288	43	hek293	hek293	PROPN
fnp-3528	288	44	/	/	SYM
fnp-3528	288	45	abca1	abca1	NOUN
fnp-3528	288	46	cells467	cells467	PROPN
fnp-3528	288	47	has	have	AUX
fnp-3528	288	48	not	not	PART
fnp-3528	288	49	been	be	AUX
fnp-3528	288	50	demonstrated	demonstrate	VERB
fnp-3528	288	51	in	in	ADP
fnp-3528	288	52	bhk-21	bhk-21	NUM
fnp-3528	288	53	/	/	SYM
fnp-3528	288	54	abca1	abca1	NOUN
fnp-3528	288	55	cells.273	cells.273	NOUN
fnp-3528	288	56	pharmacological	pharmacological	ADJ
fnp-3528	288	57	drugs	drug	NOUN
fnp-3528	288	58	interestingly	interestingly	ADV
fnp-3528	288	59	,	,	PUNCT
fnp-3528	288	60	the	the	DET
fnp-3528	288	61	experimental	experimental	ADJ
fnp-3528	288	62	anticancer	anticancer	NOUN
fnp-3528	288	63	drug	drug	NOUN
fnp-3528	288	64	serdemetan	serdemetan	ADJ
fnp-3528	288	65	(	(	PUNCT
fnp-3528	288	66	jnj-26854165	jnj-26854165	PROPN
fnp-3528	288	67	)	)	PUNCT
fnp-3528	288	68	was	be	AUX
fnp-3528	288	69	demonstrated	demonstrate	VERB
fnp-3528	288	70	to	to	PART
fnp-3528	288	71	induce	induce	VERB
fnp-3528	288	72	abca1	abca1	NOUN
fnp-3528	288	73	mrna	mrna	PROPN
fnp-3528	288	74	levels	level	NOUN
fnp-3528	288	75	but	but	CCONJ
fnp-3528	288	76	reduce	reduce	VERB
fnp-3528	288	77	abca1	abca1	NOUN
fnp-3528	288	78	-	-	PUNCT
fnp-3528	288	79	mediated	mediate	VERB
fnp-3528	288	80	cholesterol	cholesterol	NOUN
fnp-3528	288	81	efflux.468	efflux.468	NOUN
fnp-3528	288	82	the	the	DET
fnp-3528	288	83	abca1	abca1	NOUN
fnp-3528	288	84	mrna	mrna	PROPN
fnp-3528	288	85	induction	induction	NOUN
fnp-3528	288	86	was	be	AUX
fnp-3528	288	87	due	due	ADJ
fnp-3528	288	88	to	to	ADP
fnp-3528	288	89	induction	induction	NOUN
fnp-3528	288	90	of	of	ADP
fnp-3528	288	91	lxra	lxra	NOUN
fnp-3528	288	92	and	and	CCONJ
fnp-3528	288	93	lxrb	lxrb	NOUN
fnp-3528	288	94	.	.	PUNCT
fnp-3528	289	1	the	the	DET
fnp-3528	289	2	abca1	abca1	PROPN
fnp-3528	289	3	mrna	mrna	PROPN
fnp-3528	289	4	increase	increase	NOUN
fnp-3528	289	5	was	be	AUX
fnp-3528	289	6	also	also	ADV
fnp-3528	289	7	reflected	reflect	VERB
fnp-3528	289	8	at	at	ADP
fnp-3528	289	9	the	the	DET
fnp-3528	289	10	protein	protein	NOUN
fnp-3528	289	11	level	level	NOUN
fnp-3528	289	12	,	,	PUNCT
fnp-3528	289	13	which	which	PRON
fnp-3528	289	14	increased	increase	VERB
fnp-3528	289	15	within	within	ADP
fnp-3528	289	16	48	48	NUM
fnp-3528	289	17	hours	hour	NOUN
fnp-3528	289	18	of	of	ADP
fnp-3528	289	19	exposure	exposure	NOUN
fnp-3528	289	20	to	to	AUX
fnp-3528	289	21	serdemetan	serdemetan	ADJ
fnp-3528	289	22	before	before	SCONJ
fnp-3528	289	23	a	a	DET
fnp-3528	289	24	sudden	sudden	ADJ
fnp-3528	289	25	decrease	decrease	NOUN
fnp-3528	289	26	occurred	occur	VERB
fnp-3528	289	27	.	.	PUNCT
fnp-3528	290	1	the	the	DET
fnp-3528	290	2	authors	author	NOUN
fnp-3528	290	3	also	also	ADV
fnp-3528	290	4	showed	show	VERB
fnp-3528	290	5	that	that	SCONJ
fnp-3528	290	6	abca1	abca1	NOUN
fnp-3528	290	7	turnover	turnover	NOUN
fnp-3528	290	8	and	and	CCONJ
fnp-3528	290	9	degradation	degradation	NOUN
fnp-3528	290	10	were	be	AUX
fnp-3528	290	11	increased	increase	VERB
fnp-3528	290	12	.	.	PUNCT
fnp-3528	291	1	thus	thus	ADV
fnp-3528	291	2	,	,	PUNCT
fnp-3528	291	3	serdemetan	serdemetan	PROPN
fnp-3528	291	4	can	can	AUX
fnp-3528	291	5	be	be	AUX
fnp-3528	291	6	considered	consider	VERB
fnp-3528	291	7	a	a	DET
fnp-3528	291	8	destabilizer	destabilizer	NOUN
fnp-3528	291	9	.	.	PUNCT
fnp-3528	292	1	synthetic	synthetic	ADJ
fnp-3528	292	2	compounds	compound	NOUN
fnp-3528	292	3	cycloheximide	cycloheximide	NOUN
fnp-3528	292	4	was	be	AUX
fnp-3528	292	5	frequently	frequently	ADV
fnp-3528	292	6	used	use	VERB
fnp-3528	292	7	to	to	PART
fnp-3528	292	8	interrupt	interrupt	VERB
fnp-3528	292	9	intracellular	intracellular	ADJ
fnp-3528	292	10	trafficking	trafficking	NOUN
fnp-3528	292	11	of	of	ADP
fnp-3528	292	12	vesicles	vesicle	NOUN
fnp-3528	292	13	,	,	PUNCT
fnp-3528	292	14	including	include	VERB
fnp-3528	292	15	abca1	abca1	NOUN
fnp-3528	292	16	containing	contain	VERB
fnp-3528	292	17	endoand	endoand	NOUN
fnp-3528	292	18	lysosomes.387,464,468	lysosomes.387,464,468	PROPN
fnp-3528	292	19	as	as	SCONJ
fnp-3528	292	20	mentioned	mention	VERB
fnp-3528	292	21	earlier	early	ADV
fnp-3528	292	22	,	,	PUNCT
fnp-3528	292	23	abca1	abca1	PROPN
fnp-3528	292	24	is	be	AUX
fnp-3528	292	25	stabilized	stabilize	VERB
fnp-3528	292	26	by	by	ADP
fnp-3528	292	27	n	n	CCONJ
fnp-3528	292	28	-	-	PUNCT
fnp-3528	292	29	acetyl	acetyl	NOUN
fnp-3528	292	30	-	-	PUNCT
fnp-3528	292	31	leu	leu	PROPN
fnp-3528	292	32	-	-	PUNCT
fnp-3528	292	33	leu	leu	NOUN
fnp-3528	292	34	-	-	PUNCT
fnp-3528	292	35	norleucinal.316,386	norleucinal.316,386	NOUN
fnp-3528	292	36	this	this	DET
fnp-3528	292	37	stabilization	stabilization	NOUN
fnp-3528	292	38	could	could	AUX
fnp-3528	292	39	be	be	AUX
fnp-3528	292	40	abrogated	abrogate	VERB
fnp-3528	292	41	by	by	ADP
fnp-3528	292	42	the	the	DET
fnp-3528	292	43	protein	protein	NOUN
fnp-3528	292	44	kinase	kinase	NOUN
fnp-3528	292	45	c	c	PROPN
fnp-3528	292	46	inhibitor	inhibitor	NOUN
fnp-3528	292	47	gö6976	gö6976	NOUN
fnp-3528	292	48	,	,	PUNCT
fnp-3528	292	49	which	which	PRON
fnp-3528	292	50	affected	affect	VERB
fnp-3528	292	51	not	not	PART
fnp-3528	292	52	only	only	ADV
fnp-3528	292	53	abca1	abca1	NOUN
fnp-3528	292	54	protein	protein	NOUN
fnp-3528	292	55	content	content	NOUN
fnp-3528	292	56	,	,	PUNCT
fnp-3528	292	57	but	but	CCONJ
fnp-3528	292	58	also	also	ADV
fnp-3528	292	59	cholesterol	cholesterol	NOUN
fnp-3528	292	60	and	and	CCONJ
fnp-3528	292	61	phospholipid	phospholipid	NOUN
fnp-3528	292	62	transport.386	transport.386	VERB
fnp-3528	292	63	part	part	NOUN
fnp-3528	292	64	ii	ii	NOUN
fnp-3528	292	65	:	:	PUNCT
fnp-3528	292	66	pipeline	pipeline	NOUN
fnp-3528	292	67	development	development	NOUN
fnp-3528	292	68	to	to	PART
fnp-3528	292	69	gain	gain	VERB
fnp-3528	292	70	novel	novel	ADJ
fnp-3528	292	71	diagnostics	diagnostic	NOUN
fnp-3528	292	72	and	and	CCONJ
fnp-3528	292	73	therapeutics	therapeutic	NOUN
fnp-3528	292	74	in	in	ADP
fnp-3528	292	75	silico	silico	NOUN
fnp-3528	292	76	methodologies	methodology	NOUN
fnp-3528	292	77	to	to	PART
fnp-3528	292	78	predict	predict	VERB
fnp-3528	292	79	novel	novel	ADJ
fnp-3528	292	80	lead	lead	NOUN
fnp-3528	292	81	structures	structure	NOUN
fnp-3528	292	82	rational	rational	ADJ
fnp-3528	292	83	drug	drug	NOUN
fnp-3528	292	84	design	design	NOUN
fnp-3528	292	85	is	be	AUX
fnp-3528	292	86	the	the	DET
fnp-3528	292	87	innovative	innovative	ADJ
fnp-3528	292	88	process	process	NOUN
fnp-3528	292	89	of	of	ADP
fnp-3528	292	90	identifying	identify	VERB
fnp-3528	292	91	pharmaceutically	pharmaceutically	ADV
fnp-3528	292	92	relevant	relevant	ADJ
fnp-3528	292	93	drug	drug	NOUN
fnp-3528	292	94	candidates	candidate	NOUN
fnp-3528	292	95	.	.	PUNCT
fnp-3528	293	1	it	it	PRON
fnp-3528	293	2	is	be	AUX
fnp-3528	293	3	based	base	VERB
fnp-3528	293	4	on	on	ADP
fnp-3528	293	5	the	the	DET
fnp-3528	293	6	information	information	NOUN
fnp-3528	293	7	obtained	obtain	VERB
fnp-3528	293	8	in	in	ADP
fnp-3528	293	9	association	association	NOUN
fnp-3528	293	10	with	with	ADP
fnp-3528	293	11	the	the	DET
fnp-3528	293	12	drug	drug	NOUN
fnp-3528	293	13	target	target	NOUN
fnp-3528	293	14	,	,	PUNCT
fnp-3528	293	15	e.g.	e.g.	ADV
fnp-3528	293	16	,	,	PUNCT
fnp-3528	293	17	abc	abc	PROPN
fnp-3528	293	18	transporters	transporter	NOUN
fnp-3528	293	19	.	.	PUNCT
fnp-3528	294	1	in	in	ADP
fnp-3528	294	2	the	the	DET
fnp-3528	294	3	following	following	ADJ
fnp-3528	294	4	section	section	NOUN
fnp-3528	294	5	,	,	PUNCT
fnp-3528	294	6	we	we	PRON
fnp-3528	294	7	will	will	AUX
fnp-3528	294	8	discuss	discuss	VERB
fnp-3528	294	9	computational	computational	ADJ
fnp-3528	294	10	approaches	approach	NOUN
fnp-3528	294	11	for	for	ADP
fnp-3528	294	12	in	in	ADP
fnp-3528	294	13	silico	silico	NOUN
fnp-3528	294	14	operations	operation	NOUN
fnp-3528	294	15	that	that	PRON
fnp-3528	294	16	help	help	VERB
fnp-3528	294	17	to	to	PART
fnp-3528	294	18	identify	identify	VERB
fnp-3528	294	19	novel	novel	ADJ
fnp-3528	294	20	lead	lead	NOUN
fnp-3528	294	21	molecules	molecule	NOUN
fnp-3528	294	22	for	for	ADP
fnp-3528	294	23	potential	potential	ADJ
fnp-3528	294	24	diagnostic	diagnostic	ADJ
fnp-3528	294	25	and	and	CCONJ
fnp-3528	294	26	therapeutic	therapeutic	ADJ
fnp-3528	294	27	application	application	NOUN
fnp-3528	294	28	.	.	PUNCT
fnp-3528	295	1	structure	structure	NOUN
fnp-3528	295	2	-	-	PUNCT
fnp-3528	295	3	based	base	VERB
fnp-3528	295	4	drug	drug	NOUN
fnp-3528	295	5	design	design	VERB
fnp-3528	295	6	the	the	DET
fnp-3528	295	7	development	development	NOUN
fnp-3528	295	8	of	of	ADP
fnp-3528	295	9	computational	computational	ADJ
fnp-3528	295	10	methodologies	methodology	NOUN
fnp-3528	295	11	for	for	ADP
fnp-3528	295	12	structure	structure	NOUN
fnp-3528	295	13	-	-	PUNCT
fnp-3528	295	14	based	base	VERB
fnp-3528	295	15	drug	drug	NOUN
fnp-3528	295	16	design	design	NOUN
fnp-3528	295	17	to	to	PART
fnp-3528	295	18	understand	understand	VERB
fnp-3528	295	19	the	the	DET
fnp-3528	295	20	relationship	relationship	NOUN
fnp-3528	295	21	between	between	ADP
fnp-3528	295	22	transporter	transporter	NOUN
fnp-3528	295	23	sequence	sequence	NOUN
fnp-3528	295	24	/	/	SYM
fnp-3528	295	25	structure	structure	NOUN
fnp-3528	295	26	and	and	CCONJ
fnp-3528	295	27	function	function	NOUN
fnp-3528	295	28	depends	depend	VERB
fnp-3528	295	29	on	on	ADP
fnp-3528	295	30	the	the	DET
fnp-3528	295	31	availability	availability	NOUN
fnp-3528	295	32	of	of	ADP
fnp-3528	295	33	structural	structural	ADJ
fnp-3528	295	34	as	as	ADV
fnp-3528	295	35	well	well	ADV
fnp-3528	295	36	as	as	ADP
fnp-3528	295	37	biological	biological	ADJ
fnp-3528	295	38	information	information	NOUN
fnp-3528	295	39	.	.	PUNCT
fnp-3528	296	1	recent	recent	ADJ
fnp-3528	296	2	advances	advance	NOUN
fnp-3528	296	3	in	in	ADP
fnp-3528	296	4	experimental	experimental	ADJ
fnp-3528	296	5	approaches	approach	NOUN
fnp-3528	296	6	for	for	ADP
fnp-3528	296	7	structure	structure	NOUN
fnp-3528	296	8	determination	determination	NOUN
fnp-3528	296	9	have	have	AUX
fnp-3528	296	10	facilitated	facilitate	VERB
fnp-3528	296	11	high	high	ADJ
fnp-3528	296	12	-	-	PUNCT
fnp-3528	296	13	quality	quality	NOUN
fnp-3528	296	14	depictions	depiction	NOUN
fnp-3528	296	15	of	of	ADP
fnp-3528	296	16	the	the	DET
fnp-3528	296	17	structures	structure	NOUN
fnp-3528	296	18	of	of	ADP
fnp-3528	296	19	a	a	DET
fnp-3528	296	20	growing	grow	VERB
fnp-3528	296	21	number	number	NOUN
fnp-3528	296	22	of	of	ADP
fnp-3528	296	23	abc	abc	PROPN
fnp-3528	296	24	transporters	transporter	NOUN
fnp-3528	296	25	in	in	ADP
fnp-3528	296	26	different	different	ADJ
fnp-3528	296	27	conformational	conformational	ADJ
fnp-3528	296	28	states.469	states.469	NOUN
fnp-3528	296	29	these	these	DET
fnp-3528	296	30	experimental	experimental	ADJ
fnp-3528	296	31	approaches	approach	NOUN
fnp-3528	296	32	include	include	VERB
fnp-3528	296	33	in	in	ADP
fnp-3528	296	34	particular	particular	ADJ
fnp-3528	296	35	x	x	ADJ
fnp-3528	296	36	-	-	NOUN
fnp-3528	296	37	ray	ray	NOUN
fnp-3528	296	38	crystallography	crystallography	NOUN
fnp-3528	296	39	and	and	CCONJ
fnp-3528	296	40	cryo	cryo	NOUN
fnp-3528	296	41	-	-	PUNCT
fnp-3528	296	42	electron	electron	NOUN
fnp-3528	296	43	microscopy	microscopy	NOUN
fnp-3528	296	44	(	(	PUNCT
fnp-3528	296	45	cryo	cryo	NOUN
fnp-3528	296	46	-	-	PUNCT
fnp-3528	296	47	em	em	PROPN
fnp-3528	296	48	)	)	PUNCT
fnp-3528	296	49	.	.	PUNCT
fnp-3528	297	1	recently	recently	ADV
fnp-3528	297	2	,	,	PUNCT
fnp-3528	297	3	the	the	DET
fnp-3528	297	4	cryo	cryo	NOUN
fnp-3528	297	5	-	-	PUNCT
fnp-3528	297	6	em	em	PRON
fnp-3528	297	7	structures	structure	NOUN
fnp-3528	297	8	of	of	ADP
fnp-3528	297	9	human	human	ADJ
fnp-3528	297	10	abca1470	abca1470	PROPN
fnp-3528	297	11	and	and	CCONJ
fnp-3528	297	12	human	human	PROPN
fnp-3528	297	13	abca4471	abca4471	PROPN
fnp-3528	297	14	-	-	PUNCT
fnp-3528	297	15	473	473	NUM
fnp-3528	297	16	with	with	ADP
fnp-3528	297	17	resolutions	resolution	NOUN
fnp-3528	297	18	of	of	ADP
fnp-3528	297	19	4.1	4.1	NUM
fnp-3528	297	20	å	å	NOUN
fnp-3528	297	21	and	and	CCONJ
fnp-3528	297	22	3.3–3.6	3.3–3.6	NUM
fnp-3528	297	23	å	å	NOUN
fnp-3528	297	24	,	,	PUNCT
fnp-3528	297	25	respectively	respectively	ADV
fnp-3528	297	26	,	,	PUNCT
fnp-3528	297	27	were	be	AUX
fnp-3528	297	28	reported	report	VERB
fnp-3528	297	29	.	.	PUNCT
fnp-3528	298	1	in	in	ADP
fnp-3528	298	2	addition	addition	NOUN
fnp-3528	298	3	,	,	PUNCT
fnp-3528	298	4	a	a	DET
fnp-3528	298	5	cryo	cryo	NOUN
fnp-3528	298	6	-	-	PUNCT
fnp-3528	298	7	em	em	PRON
fnp-3528	298	8	structure	structure	NOUN
fnp-3528	298	9	of	of	ADP
fnp-3528	298	10	human	human	ADJ
fnp-3528	298	11	abca7	abca7	PROPN
fnp-3528	298	12	has	have	AUX
fnp-3528	298	13	been	be	AUX
fnp-3528	298	14	announced474	announced474	PROPN
fnp-3528	298	15	on	on	ADP
fnp-3528	298	16	biorxiv	biorxiv	NOUN
fnp-3528	298	17	(	(	PUNCT
fnp-3528	298	18	biorxiv.org	biorxiv.org	X
fnp-3528	298	19	)	)	PUNCT
fnp-3528	298	20	,	,	PUNCT
fnp-3528	298	21	which	which	PRON
fnp-3528	298	22	was	be	AUX
fnp-3528	298	23	,	,	PUNCT
fnp-3528	298	24	however	however	ADV
fnp-3528	298	25	,	,	PUNCT
fnp-3528	298	26	not	not	PART
fnp-3528	298	27	published	publish	VERB
fnp-3528	298	28	to	to	ADP
fnp-3528	298	29	this	this	DET
fnp-3528	298	30	date	date	NOUN
fnp-3528	298	31	(	(	PUNCT
fnp-3528	298	32	pdb	pdb	PROPN
fnp-3528	298	33	i	i	PROPN
fnp-3528	298	34	d	d	PROPN
fnp-3528	298	35	:	:	PUNCT
fnp-3528	298	36	7kqc	7kqc	NOUN
fnp-3528	298	37	)	)	PUNCT
fnp-3528	298	38	.	.	PUNCT
fnp-3528	299	1	nevertheless	nevertheless	ADV
fnp-3528	299	2	,	,	PUNCT
fnp-3528	299	3	a	a	DET
fnp-3528	299	4	homology	homology	NOUN
fnp-3528	299	5	model	model	NOUN
fnp-3528	299	6	of	of	ADP
fnp-3528	299	7	abca7	abca7	PROPN
fnp-3528	299	8	has	have	AUX
fnp-3528	299	9	been	be	AUX
fnp-3528	299	10	recently	recently	ADV
fnp-3528	299	11	developed.475	developed.475	VERB
fnp-3528	299	12	figure	figure	NOUN
fnp-3528	299	13	 	 	SPACE
fnp-3528	299	14	4	4	NUM
fnp-3528	299	15	shows	show	VERB
fnp-3528	299	16	the	the	DET
fnp-3528	299	17	structures	structure	NOUN
fnp-3528	299	18	of	of	ADP
fnp-3528	299	19	abca1	abca1	NOUN
fnp-3528	299	20	,	,	PUNCT
fnp-3528	299	21	abca4	abca4	ADJ
fnp-3528	299	22	,	,	PUNCT
fnp-3528	299	23	and	and	CCONJ
fnp-3528	299	24	abca7	abca7	NOUN
fnp-3528	299	25	as	as	SCONJ
fnp-3528	299	26	determined	determine	VERB
fnp-3528	299	27	by	by	ADP
fnp-3528	299	28	cryo	cryo	PROPN
fnp-3528	299	29	-	-	PUNCT
fnp-3528	299	30	em	em	PRON
fnp-3528	299	31	as	as	ADV
fnp-3528	299	32	well	well	ADV
fnp-3528	299	33	as	as	ADP
fnp-3528	299	34	homology	homology	NOUN
fnp-3528	299	35	modelling	modelling	NOUN
fnp-3528	299	36	.	.	PUNCT
fnp-3528	300	1	figure	figure	NOUN
fnp-3528	300	2	 	 	SPACE
fnp-3528	300	3	4	4	NUM
fnp-3528	300	4	.	.	PUNCT
fnp-3528	300	5	available	available	ADJ
fnp-3528	300	6	structures	structure	NOUN
fnp-3528	300	7	of	of	ADP
fnp-3528	300	8	abca	abca	NOUN
fnp-3528	300	9	transporters	transporter	NOUN
fnp-3528	300	10	:	:	PUNCT
fnp-3528	300	11	the	the	DET
fnp-3528	300	12	cryo	cryo	NOUN
fnp-3528	300	13	-	-	PUNCT
fnp-3528	300	14	em	em	PRON
fnp-3528	300	15	structures	structure	NOUN
fnp-3528	300	16	of	of	ADP
fnp-3528	300	17	human	human	ADJ
fnp-3528	300	18	abca1470	abca1470	PROPN
fnp-3528	300	19	(	(	PUNCT
fnp-3528	300	20	very	very	ADV
fnp-3528	300	21	left	left	ADJ
fnp-3528	300	22	;	;	PUNCT
fnp-3528	300	23	pdb	pdb	PROPN
fnp-3528	300	24	i	i	PROPN
fnp-3528	300	25	d	d	PROPN
fnp-3528	300	26	5xjy	5xjy	NUM
fnp-3528	300	27	)	)	PUNCT
fnp-3528	300	28	and	and	CCONJ
fnp-3528	300	29	abca4	abca4	VERB
fnp-3528	301	1	[	[	X
fnp-3528	301	2	left	leave	VERB
fnp-3528	301	3	(	(	PUNCT
fnp-3528	301	4	pdb	pdb	PROPN
fnp-3528	301	5	i	i	PROPN
fnp-3528	301	6	d	d	PROPN
fnp-3528	301	7	7lkp	7lkp	PROPN
fnp-3528	301	8	,	,	PUNCT
fnp-3528	301	9	middle	middle	NOUN
fnp-3528	301	10	(	(	PUNCT
fnp-3528	301	11	pdb	pdb	PROPN
fnp-3528	301	12	i	i	PROPN
fnp-3528	301	13	d	d	PROPN
fnp-3528	301	14	7e7i	7e7i	NUM
fnp-3528	301	15	)	)	PUNCT
fnp-3528	301	16	,	,	PUNCT
fnp-3528	301	17	and	and	CCONJ
fnp-3528	301	18	right	right	INTJ
fnp-3528	301	19	(	(	PUNCT
fnp-3528	301	20	pdb	pdb	PROPN
fnp-3528	301	21	i	i	PROPN
fnp-3528	301	22	d	d	PROPN
fnp-3528	301	23	7m1q)]471	7m1q)]471	PROPN
fnp-3528	301	24	-	-	SYM
fnp-3528	301	25	473	473	NUM
fnp-3528	301	26	as	as	ADV
fnp-3528	301	27	well	well	ADV
fnp-3528	301	28	as	as	ADP
fnp-3528	301	29	the	the	DET
fnp-3528	301	30	homology	homology	NOUN
fnp-3528	301	31	model	model	NOUN
fnp-3528	301	32	developed	develop	VERB
fnp-3528	301	33	for	for	ADP
fnp-3528	301	34	human	human	ADJ
fnp-3528	301	35	abca7	abca7	NOUN
fnp-3528	301	36	(	(	PUNCT
fnp-3528	301	37	very	very	ADV
fnp-3528	301	38	right).475	right).475	PROPN
fnp-3528	301	39	all	all	DET
fnp-3528	301	40	three	three	NUM
fnp-3528	301	41	transporters	transporter	NOUN
fnp-3528	301	42	are	be	AUX
fnp-3528	301	43	typical	typical	ADJ
fnp-3528	301	44	abca	abca	NOUN
fnp-3528	301	45	transporters	transporter	NOUN
fnp-3528	301	46	with	with	ADP
fnp-3528	301	47	three	three	NUM
fnp-3528	301	48	crucial	crucial	ADJ
fnp-3528	301	49	structural	structural	ADJ
fnp-3528	301	50	parts	part	NOUN
fnp-3528	301	51	:	:	PUNCT
fnp-3528	301	52	two	two	NUM
fnp-3528	301	53	nucleotide	nucleotide	NOUN
fnp-3528	301	54	-	-	PUNCT
fnp-3528	301	55	binding	bind	VERB
fnp-3528	301	56	domains	domain	NOUN
fnp-3528	301	57	(	(	PUNCT
fnp-3528	301	58	nbds	nbds	NOUN
fnp-3528	301	59	;	;	PUNCT
fnp-3528	301	60	intracellular	intracellular	ADJ
fnp-3528	301	61	)	)	PUNCT
fnp-3528	301	62	,	,	PUNCT
fnp-3528	301	63	two	two	NUM
fnp-3528	301	64	membrane	membrane	NOUN
fnp-3528	301	65	-	-	PUNCT
fnp-3528	301	66	spanning	span	VERB
fnp-3528	301	67	domains	domain	NOUN
fnp-3528	301	68	[	[	X
fnp-3528	301	69	msds	msds	NOUN
fnp-3528	301	70	(	(	PUNCT
fnp-3528	301	71	2	2	NUM
fnp-3528	301	72	x	x	SYM
fnp-3528	301	73	6	6	NUM
fnp-3528	301	74	transmembrane	transmembrane	NOUN
fnp-3528	301	75	helices	helix	NOUN
fnp-3528	301	76	tms	tms	PROPN
fnp-3528	301	77	)	)	PUNCT
fnp-3528	301	78	;	;	PUNCT
fnp-3528	301	79	inter	inter	ADJ
fnp-3528	301	80	-	-	ADJ
fnp-3528	301	81	membrane	membrane	ADJ
fnp-3528	301	82	space	space	NOUN
fnp-3528	301	83	]	]	PUNCT
fnp-3528	301	84	,	,	PUNCT
fnp-3528	301	85	and	and	CCONJ
fnp-3528	301	86	two	two	NUM
fnp-3528	301	87	large	large	ADJ
fnp-3528	301	88	extracellular	extracellular	ADJ
fnp-3528	301	89	domains	domain	NOUN
fnp-3528	301	90	(	(	PUNCT
fnp-3528	301	91	ecds	ecds	NOUN
fnp-3528	301	92	;	;	PUNCT
fnp-3528	301	93	extracellular	extracellular	ADJ
fnp-3528	301	94	)	)	PUNCT
fnp-3528	301	95	.	.	PUNCT
fnp-3528	302	1	considering	consider	VERB
fnp-3528	302	2	the	the	DET
fnp-3528	302	3	available	available	ADJ
fnp-3528	302	4	structural	structural	ADJ
fnp-3528	302	5	knowledge	knowledge	NOUN
fnp-3528	302	6	,	,	PUNCT
fnp-3528	302	7	a	a	DET
fnp-3528	302	8	‘	'	PUNCT
fnp-3528	302	9	common	common	ADJ
fnp-3528	302	10	’	'	PUNCT
fnp-3528	302	11	abca	abca	NOUN
fnp-3528	302	12	transporter	transporter	NOUN
fnp-3528	302	13	possesses	possess	VERB
fnp-3528	302	14	a	a	DET
fnp-3528	302	15	very	very	ADV
fnp-3528	302	16	long	long	ADJ
fnp-3528	302	17	amino	amino	NOUN
fnp-3528	302	18	acid	acid	NOUN
fnp-3528	302	19	sequence	sequence	NOUN
fnp-3528	302	20	(	(	PUNCT
fnp-3528	302	21	>	>	SYM
fnp-3528	302	22	2000	2000	NUM
fnp-3528	302	23	amino	amino	NOUN
fnp-3528	302	24	acids	acid	NOUN
fnp-3528	302	25	)	)	PUNCT
fnp-3528	302	26	and	and	CCONJ
fnp-3528	302	27	consists	consist	VERB
fnp-3528	302	28	of	of	ADP
fnp-3528	302	29	two	two	NUM
fnp-3528	302	30	membrane	membrane	NOUN
fnp-3528	302	31	-	-	PUNCT
fnp-3528	302	32	spanning	span	VERB
fnp-3528	302	33	domains	domain	NOUN
fnp-3528	302	34	(	(	PUNCT
fnp-3528	302	35	msd1	msd1	PROPN
fnp-3528	302	36	and	and	CCONJ
fnp-3528	302	37	msd2	msd2	PROPN
fnp-3528	302	38	)	)	PUNCT
fnp-3528	302	39	each	each	PRON
fnp-3528	302	40	composed	compose	VERB
fnp-3528	302	41	of	of	ADP
fnp-3528	302	42	six	six	NUM
fnp-3528	302	43	transmembrane	transmembrane	ADJ
fnp-3528	302	44	helices	helix	NOUN
fnp-3528	302	45	(	(	PUNCT
fnp-3528	302	46	tm1–6	tm1–6	PROPN
fnp-3528	302	47	and	and	CCONJ
fnp-3528	302	48	tm7–12	tm7–12	PROPN
fnp-3528	302	49	)	)	PUNCT
fnp-3528	302	50	.	.	PUNCT
fnp-3528	303	1	these	these	DET
fnp-3528	303	2	msds	msds	PROPN
fnp-3528	303	3	are	be	AUX
fnp-3528	303	4	followed	follow	VERB
fnp-3528	303	5	by	by	ADP
fnp-3528	303	6	a	a	DET
fnp-3528	303	7	cytoplasmic	cytoplasmic	ADJ
fnp-3528	303	8	region	region	NOUN
fnp-3528	303	9	comprising	comprise	VERB
fnp-3528	303	10	a	a	DET
fnp-3528	303	11	nucleotide	nucleotide	NOUN
fnp-3528	303	12	-	-	PUNCT
fnp-3528	303	13	binding	bind	VERB
fnp-3528	303	14	domain	domain	NOUN
fnp-3528	303	15	(	(	PUNCT
fnp-3528	303	16	nbd1	nbd1	NOUN
fnp-3528	303	17	and	and	CCONJ
fnp-3528	303	18	nbd2	nbd2	NOUN
fnp-3528	303	19	)	)	PUNCT
fnp-3528	303	20	and	and	CCONJ
fnp-3528	303	21	a	a	DET
fnp-3528	303	22	small	small	ADJ
fnp-3528	303	23	regulatory	regulatory	NOUN
fnp-3528	303	24	(	(	PUNCT
fnp-3528	303	25	r1	r1	NOUN
fnp-3528	303	26	and	and	CCONJ
fnp-3528	303	27	r2	r2	NOUN
fnp-3528	303	28	)	)	PUNCT
fnp-3528	303	29	domain	domain	NOUN
fnp-3528	303	30	,	,	PUNCT
fnp-3528	303	31	which	which	PRON
fnp-3528	303	32	have	have	AUX
fnp-3528	303	33	been	be	AUX
fnp-3528	303	34	proposed	propose	VERB
fnp-3528	303	35	to	to	PART
fnp-3528	303	36	stabilize	stabilize	VERB
fnp-3528	303	37	the	the	DET
fnp-3528	303	38	interaction	interaction	NOUN
fnp-3528	303	39	between	between	ADP
fnp-3528	303	40	nbd1	nbd1	PROPN
fnp-3528	303	41	and	and	CCONJ
fnp-3528	303	42	nbd2470,473	nbd2470,473	NOUN
fnp-3528	303	43	and	and	CCONJ
fnp-3528	303	44	were	be	AUX
fnp-3528	303	45	found	find	VERB
fnp-3528	303	46	to	to	PART
fnp-3528	303	47	strongly	strongly	ADV
fnp-3528	303	48	interact	interact	VERB
fnp-3528	303	49	with	with	ADP
fnp-3528	303	50	each	each	DET
fnp-3528	303	51	another	another	PRON
fnp-3528	303	52	in	in	ADP
fnp-3528	303	53	the	the	DET
fnp-3528	303	54	absence	absence	NOUN
fnp-3528	303	55	of	of	ADP
fnp-3528	303	56	atp.471,472	atp.471,472	NOUN
fnp-3528	303	57	abca	abca	NOUN
fnp-3528	303	58	transporters	transporter	NOUN
fnp-3528	303	59	are	be	AUX
fnp-3528	303	60	‘	'	PUNCT
fnp-3528	303	61	type	type	NOUN
fnp-3528	303	62	ii	ii	NOUN
fnp-3528	303	63	transporters	transporter	NOUN
fnp-3528	303	64	’	'	PUNCT
fnp-3528	303	65	in	in	ADP
fnp-3528	303	66	which	which	PRON
fnp-3528	303	67	the	the	DET
fnp-3528	303	68	msds	msds	PROPN
fnp-3528	303	69	indeed	indeed	ADV
fnp-3528	303	70	form	form	VERB
fnp-3528	303	71	a	a	DET
fnp-3528	303	72	tunnel	tunnel	NOUN
fnp-3528	303	73	for	for	ADP
fnp-3528	303	74	substrate	substrate	NOUN
fnp-3528	303	75	translocation	translocation	NOUN
fnp-3528	303	76	from	from	ADP
fnp-3528	303	77	the	the	DET
fnp-3528	303	78	cytosol	cytosol	NOUN
fnp-3528	303	79	to	to	ADP
fnp-3528	303	80	the	the	DET
fnp-3528	303	81	lumen	luman	NOUN
fnp-3528	303	82	,	,	PUNCT
fnp-3528	303	83	however	however	ADV
fnp-3528	303	84	,	,	PUNCT
fnp-3528	303	85	represent	represent	VERB
fnp-3528	303	86	separate	separate	ADJ
fnp-3528	303	87	entities	entity	NOUN
fnp-3528	303	88	without	without	ADP
fnp-3528	303	89	swapping	swap	VERB
fnp-3528	303	90	/	/	SYM
fnp-3528	303	91	twisting	twisting	NOUN
fnp-3528	303	92	of	of	ADP
fnp-3528	303	93	the	the	DET
fnp-3528	303	94	msds	msds	NOUN
fnp-3528	303	95	,	,	PUNCT
fnp-3528	303	96	as	as	SCONJ
fnp-3528	303	97	this	this	PRON
fnp-3528	303	98	is	be	AUX
fnp-3528	303	99	the	the	DET
fnp-3528	303	100	case	case	NOUN
fnp-3528	303	101	with	with	ADP
fnp-3528	303	102	classical	classical	ADJ
fnp-3528	303	103	‘	'	PUNCT
fnp-3528	303	104	type	type	NOUN
fnp-3528	303	105	i	i	PRON
fnp-3528	303	106	transporters	transporter	NOUN
fnp-3528	303	107	’	'	PUNCT
fnp-3528	303	108	like	like	ADP
fnp-3528	303	109	abcb1.476	abcb1.476	PRON
fnp-3528	303	110	most	most	ADJ
fnp-3528	303	111	tms	tms	PROPN
fnp-3528	303	112	are	be	AUX
fnp-3528	303	113	completely	completely	ADV
fnp-3528	303	114	exposed	expose	VERB
fnp-3528	303	115	to	to	ADP
fnp-3528	303	116	the	the	DET
fnp-3528	303	117	hydrophobic	hydrophobic	NOUN
fnp-3528	303	118	environment	environment	NOUN
fnp-3528	303	119	of	of	ADP
fnp-3528	303	120	the	the	DET
fnp-3528	303	121	membrane	membrane	NOUN
fnp-3528	303	122	,	,	PUNCT
fnp-3528	303	123	which	which	PRON
fnp-3528	303	124	could	could	AUX
fnp-3528	303	125	promote	promote	VERB
fnp-3528	303	126	the	the	DET
fnp-3528	303	127	attraction	attraction	NOUN
fnp-3528	303	128	and	and	CCONJ
fnp-3528	303	129	binding	binding	NOUN
fnp-3528	303	130	of	of	ADP
fnp-3528	303	131	fat	fat	ADJ
fnp-3528	303	132	-	-	PUNCT
fnp-3528	303	133	soluble	soluble	ADJ
fnp-3528	303	134	cholesterol	cholesterol	NOUN
fnp-3528	303	135	as	as	ADV
fnp-3528	303	136	well	well	ADV
fnp-3528	303	137	as	as	ADP
fnp-3528	303	138	phospholipids	phospholipid	NOUN
fnp-3528	303	139	before	before	ADP
fnp-3528	303	140	guidance	guidance	NOUN
fnp-3528	303	141	to	to	ADP
fnp-3528	303	142	and	and	CCONJ
fnp-3528	303	143	through	through	ADP
fnp-3528	303	144	the	the	DET
fnp-3528	303	145	substrate	substrate	NOUN
fnp-3528	303	146	translocation	translocation	NOUN
fnp-3528	303	147	tunnel	tunnel	NOUN
fnp-3528	303	148	,	,	PUNCT
fnp-3528	303	149	and	and	CCONJ
fnp-3528	303	150	which	which	PRON
fnp-3528	303	151	hosts	host	VERB
fnp-3528	303	152	several	several	ADJ
fnp-3528	303	153	cholesterol	cholesterol	NOUN
fnp-3528	303	154	and	and	CCONJ
fnp-3528	303	155	phospholipid	phospholipid	NOUN
fnp-3528	303	156	binding	bind	VERB
fnp-3528	303	157	sites.470	sites.470	NOUN
fnp-3528	303	158	-	-	PUNCT
fnp-3528	303	159	474	474	NUM
fnp-3528	303	160	a	a	DET
fnp-3528	303	161	unique	unique	ADJ
fnp-3528	303	162	feature	feature	NOUN
fnp-3528	303	163	amongst	amongst	ADP
fnp-3528	303	164	abca	abca	PROPN
fnp-3528	303	165	transporters	transporter	NOUN
fnp-3528	303	166	in	in	ADP
fnp-3528	303	167	comparison	comparison	NOUN
fnp-3528	303	168	to	to	ADP
fnp-3528	303	169	other	other	ADJ
fnp-3528	303	170	abc	abc	PROPN
fnp-3528	303	171	transporters	transporter	NOUN
fnp-3528	303	172	is	be	AUX
fnp-3528	303	173	the	the	DET
fnp-3528	303	174	existence	existence	NOUN
fnp-3528	303	175	of	of	ADP
fnp-3528	303	176	two	two	NUM
fnp-3528	303	177	large	large	ADJ
fnp-3528	303	178	extracellular	extracellular	ADJ
fnp-3528	303	179	domains	domain	NOUN
fnp-3528	303	180	(	(	PUNCT
fnp-3528	303	181	ecd1	ecd1	NOUN
fnp-3528	303	182	and	and	CCONJ
fnp-3528	303	183	ecd2	ecd2	PROPN
fnp-3528	303	184	)	)	PUNCT
fnp-3528	303	185	.	.	PUNCT
fnp-3528	304	1	these	these	DET
fnp-3528	304	2	domains	domain	NOUN
fnp-3528	304	3	together	together	ADV
fnp-3528	304	4	form	form	VERB
fnp-3528	304	5	a	a	DET
fnp-3528	304	6	channel	channel	NOUN
fnp-3528	304	7	embedded	embed	VERB
fnp-3528	304	8	in	in	ADP
fnp-3528	304	9	hydrophobic	hydrophobic	NOUN
fnp-3528	304	10	amino	amino	NOUN
fnp-3528	304	11	acids470	acids470	PROPN
fnp-3528	304	12	-	-	PUNCT
fnp-3528	304	13	472	472	NUM
fnp-3528	304	14	and	and	CCONJ
fnp-3528	304	15	are	be	AUX
fnp-3528	304	16	believed	believe	VERB
fnp-3528	304	17	to	to	PART
fnp-3528	304	18	facilitate	facilitate	VERB
fnp-3528	304	19	intermediate	intermediate	ADJ
fnp-3528	304	20	storage	storage	NOUN
fnp-3528	304	21	of	of	ADP
fnp-3528	304	22	cholesterol470	cholesterol470	PROPN
fnp-3528	304	23	and	and	CCONJ
fnp-3528	304	24	phospholipids	phospholipid	NOUN
fnp-3528	304	25	.	.	PUNCT
fnp-3528	305	1	they	they	PRON
fnp-3528	305	2	have	have	AUX
fnp-3528	305	3	also	also	ADV
fnp-3528	305	4	been	be	AUX
fnp-3528	305	5	suggested	suggest	VERB
fnp-3528	305	6	as	as	ADP
fnp-3528	305	7	the	the	DET
fnp-3528	305	8	primary	primary	ADJ
fnp-3528	305	9	binding	bind	VERB
fnp-3528	305	10	site	site	NOUN
fnp-3528	305	11	of	of	ADP
fnp-3528	305	12	apoa1,471,477	apoa1,471,477	NOUN
fnp-3528	305	13	as	as	SCONJ
fnp-3528	305	14	indicated	indicate	VERB
fnp-3528	305	15	by	by	ADP
fnp-3528	305	16	the	the	DET
fnp-3528	305	17	latest	late	ADJ
fnp-3528	305	18	data	datum	NOUN
fnp-3528	305	19	on	on	ADP
fnp-3528	305	20	abca4.471	abca4.471	ADJ
fnp-3528	305	21	a	a	DET
fnp-3528	305	22	large	large	ADJ
fnp-3528	305	23	gap	gap	NOUN
fnp-3528	305	24	exists	exist	VERB
fnp-3528	305	25	between	between	ADP
fnp-3528	305	26	the	the	DET
fnp-3528	305	27	ecds	ecds	NOUN
fnp-3528	305	28	and	and	CCONJ
fnp-3528	305	29	msds	msds	NOUN
fnp-3528	305	30	,	,	PUNCT
fnp-3528	305	31	pointing	point	VERB
fnp-3528	305	32	to	to	ADP
fnp-3528	305	33	strong	strong	ADJ
fnp-3528	305	34	conformational	conformational	ADJ
fnp-3528	305	35	changes	change	NOUN
fnp-3528	305	36	that	that	PRON
fnp-3528	305	37	are	be	AUX
fnp-3528	305	38	required	require	VERB
fnp-3528	305	39	for	for	ADP
fnp-3528	305	40	abca	abca	NOUN
fnp-3528	305	41	transporter	transporter	NOUN
fnp-3528	305	42	function.470	function.470	NOUN
fnp-3528	305	43	another	another	DET
fnp-3528	305	44	common	common	ADJ
fnp-3528	305	45	feature	feature	NOUN
fnp-3528	305	46	amongst	amongst	ADP
fnp-3528	305	47	abca	abca	PROPN
fnp-3528	305	48	transporters	transporter	NOUN
fnp-3528	305	49	are	be	AUX
fnp-3528	305	50	four	four	NUM
fnp-3528	305	51	intracellular	intracellular	ADJ
fnp-3528	305	52	and	and	CCONJ
fnp-3528	305	53	extracellular	extracellular	ADJ
fnp-3528	305	54	helices	helix	NOUN
fnp-3528	305	55	(	(	PUNCT
fnp-3528	305	56	ih1–4	ih1–4	NOUN
fnp-3528	305	57	and	and	CCONJ
fnp-3528	305	58	eh1–4	eh1–4	PROPN
fnp-3528	305	59	)	)	PUNCT
fnp-3528	305	60	,	,	PUNCT
fnp-3528	305	61	which	which	PRON
fnp-3528	305	62	are	be	AUX
fnp-3528	305	63	believed	believe	VERB
fnp-3528	305	64	to	to	PART
fnp-3528	305	65	provide	provide	VERB
fnp-3528	305	66	the	the	DET
fnp-3528	305	67	necessary	necessary	ADJ
fnp-3528	305	68	flexibility	flexibility	NOUN
fnp-3528	305	69	for	for	ADP
fnp-3528	305	70	interaction	interaction	NOUN
fnp-3528	305	71	between	between	ADP
fnp-3528	305	72	the	the	DET
fnp-3528	305	73	msds	msds	NOUN
fnp-3528	305	74	and	and	CCONJ
fnp-3528	305	75	nbds	nbds	NOUN
fnp-3528	305	76	in	in	ADP
fnp-3528	305	77	the	the	DET
fnp-3528	305	78	substrate	substrate	NOUN
fnp-3528	305	79	translocation	translocation	NOUN
fnp-3528	305	80	process,478	process,478	PROPN
fnp-3528	305	81	and	and	CCONJ
fnp-3528	305	82	were	be	AUX
fnp-3528	305	83	suggested	suggest	VERB
fnp-3528	305	84	to	to	PART
fnp-3528	305	85	enable	enable	VERB
fnp-3528	305	86	proper	proper	ADJ
fnp-3528	305	87	folding	folding	NOUN
fnp-3528	305	88	and	and	CCONJ
fnp-3528	305	89	function	function	NOUN
fnp-3528	305	90	of	of	ADP
fnp-3528	305	91	these	these	DET
fnp-3528	305	92	transporters.471	transporters.471	NOUN
fnp-3528	305	93	of	of	ADP
fnp-3528	305	94	important	important	ADJ
fnp-3528	305	95	note	note	NOUN
fnp-3528	305	96	is	be	AUX
fnp-3528	305	97	that	that	DET
fnp-3528	305	98	abca1	abca1	NOUN
fnp-3528	305	99	and	and	CCONJ
fnp-3528	305	100	abca4	abca4	VERB
fnp-3528	305	101	share	share	NOUN
fnp-3528	305	102	sequential	sequential	ADJ
fnp-3528	305	103	and	and	CCONJ
fnp-3528	305	104	structural	structural	ADJ
fnp-3528	305	105	similarities	similarity	NOUN
fnp-3528	305	106	with	with	ADP
fnp-3528	305	107	the	the	DET
fnp-3528	305	108	abcg	abcg	ADJ
fnp-3528	305	109	family	family	NOUN
fnp-3528	305	110	,	,	PUNCT
fnp-3528	305	111	in	in	ADP
fnp-3528	305	112	particular	particular	ADJ
fnp-3528	305	113	with	with	ADP
fnp-3528	305	114	abcg5	abcg5	PROPN
fnp-3528	305	115	/	/	SYM
fnp-3528	305	116	abcg8,470	abcg8,470	PROPN
fnp-3528	305	117	which	which	PRON
fnp-3528	305	118	is	be	AUX
fnp-3528	305	119	the	the	DET
fnp-3528	305	120	model	model	NOUN
fnp-3528	305	121	type	type	PROPN
fnp-3528	305	122	ii	ii	PROPN
fnp-3528	305	123	transporter.478	transporter.478	NOUN
fnp-3528	305	124	this	this	DET
fnp-3528	305	125	similarity	similarity	NOUN
fnp-3528	305	126	suggests	suggest	VERB
fnp-3528	305	127	an	an	DET
fnp-3528	305	128	evolutionary	evolutionary	ADJ
fnp-3528	305	129	relevance	relevance	NOUN
fnp-3528	305	130	amongst	amongst	ADP
fnp-3528	305	131	various	various	ADJ
fnp-3528	305	132	abc	abc	PROPN
fnp-3528	305	133	transporter	transporter	NOUN
fnp-3528	305	134	subfamilies	subfamily	NOUN
fnp-3528	305	135	.	.	PUNCT
fnp-3528	306	1	more	more	ADV
fnp-3528	306	2	importantly	importantly	ADV
fnp-3528	306	3	,	,	PUNCT
fnp-3528	306	4	conserved	conserve	VERB
fnp-3528	306	5	sequential	sequential	ADJ
fnp-3528	306	6	and	and	CCONJ
fnp-3528	306	7	structural	structural	ADJ
fnp-3528	306	8	similarities	similarity	NOUN
fnp-3528	306	9	also	also	ADV
fnp-3528	306	10	support	support	VERB
fnp-3528	306	11	the	the	DET
fnp-3528	306	12	translation	translation	NOUN
fnp-3528	306	13	of	of	ADP
fnp-3528	306	14	knowledge	knowledge	NOUN
fnp-3528	306	15	gained	gain	VERB
fnp-3528	306	16	on	on	ADP
fnp-3528	306	17	other	other	ADJ
fnp-3528	306	18	abc	abc	PROPN
fnp-3528	306	19	transporter	transporter	NOUN
fnp-3528	306	20	subfamilies	subfamily	NOUN
fnp-3528	306	21	to	to	ADP
fnp-3528	306	22	abca	abca	PROPN
fnp-3528	306	23	transporters.470,472	transporters.470,472	NOUN
fnp-3528	306	24	this	this	PRON
fnp-3528	306	25	is	be	AUX
fnp-3528	306	26	of	of	ADP
fnp-3528	306	27	particular	particular	ADJ
fnp-3528	306	28	interest	interest	NOUN
fnp-3528	306	29	when	when	SCONJ
fnp-3528	306	30	novel	novel	ADJ
fnp-3528	306	31	lead	lead	NOUN
fnp-3528	306	32	structures	structure	NOUN
fnp-3528	306	33	for	for	ADP
fnp-3528	306	34	new	new	ADJ
fnp-3528	306	35	pharmacological	pharmacological	ADJ
fnp-3528	306	36	targets	target	NOUN
fnp-3528	306	37	,	,	PUNCT
fnp-3528	306	38	in	in	ADP
fnp-3528	306	39	this	this	DET
fnp-3528	306	40	case	case	NOUN
fnp-3528	306	41	under	under	ADV
fnp-3528	306	42	-	-	PUNCT
fnp-3528	306	43	studied	study	VERB
fnp-3528	306	44	abc	abc	PROPN
fnp-3528	306	45	transporters,18	transporters,18	NOUN
fnp-3528	306	46	are	be	AUX
fnp-3528	306	47	focused,6,18	focused,6,18	PROPN
fnp-3528	306	48	and	and	CCONJ
fnp-3528	306	49	specific	specific	ADJ
fnp-3528	306	50	binding	bind	VERB
fnp-3528	306	51	sites	site	NOUN
fnp-3528	306	52	located	locate	VERB
fnp-3528	306	53	within	within	ADP
fnp-3528	306	54	the	the	DET
fnp-3528	306	55	msds	msds	NOUN
fnp-3528	306	56	or	or	CCONJ
fnp-3528	306	57	nbds	nbds	NOUN
fnp-3528	306	58	are	be	AUX
fnp-3528	306	59	targeted	target	VERB
fnp-3528	306	60	.	.	PUNCT
fnp-3528	307	1	based	base	VERB
fnp-3528	307	2	on	on	ADP
fnp-3528	307	3	the	the	DET
fnp-3528	307	4	sequence	sequence	NOUN
fnp-3528	307	5	information	information	NOUN
fnp-3528	307	6	of	of	ADP
fnp-3528	307	7	abc	abc	PROPN
fnp-3528	307	8	transporters	transporter	NOUN
fnp-3528	307	9	within	within	ADP
fnp-3528	307	10	the	the	DET
fnp-3528	307	11	same	same	ADJ
fnp-3528	307	12	family	family	NOUN
fnp-3528	307	13	,	,	PUNCT
fnp-3528	307	14	homology	homology	NOUN
fnp-3528	307	15	-	-	PUNCT
fnp-3528	307	16	modeling	modeling	NOUN
fnp-3528	307	17	techniques	technique	NOUN
fnp-3528	307	18	are	be	AUX
fnp-3528	307	19	the	the	DET
fnp-3528	307	20	preferred	prefer	VERB
fnp-3528	307	21	choice	choice	NOUN
fnp-3528	307	22	for	for	ADP
fnp-3528	307	23	structure	structure	NOUN
fnp-3528	307	24	determination	determination	NOUN
fnp-3528	307	25	and	and	CCONJ
fnp-3528	307	26	binding	bind	VERB
fnp-3528	307	27	site	site	NOUN
fnp-3528	307	28	elucidation	elucidation	NOUN
fnp-3528	307	29	if	if	SCONJ
fnp-3528	307	30	these	these	DET
fnp-3528	307	31	subtypes	subtype	NOUN
fnp-3528	307	32	do	do	AUX
fnp-3528	307	33	not	not	PART
fnp-3528	307	34	yield	yield	VERB
fnp-3528	307	35	x	x	NOUN
fnp-3528	307	36	-	-	NOUN
fnp-3528	307	37	ray	ray	NOUN
fnp-3528	307	38	or	or	CCONJ
fnp-3528	307	39	cryo	cryo	NOUN
fnp-3528	307	40	-	-	PUNCT
fnp-3528	307	41	em	em	PRON
fnp-3528	307	42	structures	structure	NOUN
fnp-3528	307	43	.	.	PUNCT
fnp-3528	308	1	this	this	DET
fnp-3528	308	2	methodology	methodology	NOUN
fnp-3528	308	3	is	be	AUX
fnp-3528	308	4	of	of	ADP
fnp-3528	308	5	particular	particular	ADJ
fnp-3528	308	6	relevance	relevance	NOUN
fnp-3528	308	7	for	for	ADP
fnp-3528	308	8	closely	closely	ADV
fnp-3528	308	9	related	relate	VERB
fnp-3528	308	10	homologs	homolog	NOUN
fnp-3528	308	11	with	with	ADP
fnp-3528	308	12	high	high	ADJ
fnp-3528	308	13	medical	medical	ADJ
fnp-3528	308	14	relevance,198	relevance,198	NOUN
fnp-3528	308	15	such	such	ADJ
fnp-3528	308	16	as	as	ADP
fnp-3528	308	17	abca7	abca7	PROPN
fnp-3528	308	18	(	(	PUNCT
fnp-3528	308	19	similarity	similarity	NOUN
fnp-3528	308	20	a1	a1	PROPN
fnp-3528	308	21	/	/	SYM
fnp-3528	308	22	a7	a7	PROPN
fnp-3528	308	23	:	:	PUNCT
fnp-3528	308	24	54	54	NUM
fnp-3528	308	25	%	%	NOUN
fnp-3528	308	26	;	;	PUNCT
fnp-3528	308	27	similarity	similarity	NOUN
fnp-3528	308	28	a4	a4	PROPN
fnp-3528	308	29	/	/	SYM
fnp-3528	308	30	a7	a7	PROPN
fnp-3528	308	31	:	:	PUNCT
fnp-3528	308	32	49%).200	49%).200	NUM
fnp-3528	308	33	the	the	DET
fnp-3528	308	34	generated	generate	VERB
fnp-3528	308	35	homology	homology	NOUN
fnp-3528	308	36	models	model	NOUN
fnp-3528	308	37	can	can	AUX
fnp-3528	308	38	be	be	AUX
fnp-3528	308	39	refined	refine	VERB
fnp-3528	308	40	further	far	ADV
fnp-3528	308	41	by	by	ADP
fnp-3528	308	42	molecular	molecular	ADJ
fnp-3528	308	43	dynamics	dynamic	NOUN
fnp-3528	308	44	simulation	simulation	NOUN
fnp-3528	308	45	,	,	PUNCT
fnp-3528	308	46	in	in	ADP
fnp-3528	308	47	which	which	PRON
fnp-3528	308	48	the	the	DET
fnp-3528	308	49	transporter	transporter	NOUN
fnp-3528	308	50	movement	movement	NOUN
fnp-3528	308	51	(	(	PUNCT
fnp-3528	308	52	‘	'	PUNCT
fnp-3528	308	53	trajectory	trajectory	NOUN
fnp-3528	308	54	’	'	PUNCT
fnp-3528	308	55	)	)	PUNCT
fnp-3528	308	56	is	be	AUX
fnp-3528	308	57	simulated	simulate	VERB
fnp-3528	308	58	to	to	PART
fnp-3528	308	59	potentially	potentially	ADV
fnp-3528	308	60	unravel	unravel	VERB
fnp-3528	308	61	relevant	relevant	ADJ
fnp-3528	308	62	transporter	transporter	NOUN
fnp-3528	308	63	conformations	conformation	NOUN
fnp-3528	308	64	.	.	PUNCT
fnp-3528	309	1	very	very	ADV
fnp-3528	309	2	recently	recently	ADV
fnp-3528	309	3	,	,	PUNCT
fnp-3528	309	4	potential	potential	ADJ
fnp-3528	309	5	abca1	abca1	NOUN
fnp-3528	309	6	drug	drug	NOUN
fnp-3528	309	7	binding	bind	VERB
fnp-3528	309	8	sites	site	NOUN
fnp-3528	309	9	have	have	AUX
fnp-3528	309	10	been	be	AUX
fnp-3528	309	11	proposed	propose	VERB
fnp-3528	309	12	by	by	ADP
fnp-3528	309	13	this	this	DET
fnp-3528	309	14	methodology,479	methodology,479	PROPN
fnp-3528	309	15	and	and	CCONJ
fnp-3528	309	16	an	an	DET
fnp-3528	309	17	abca7	abca7	PROPN
fnp-3528	309	18	homology	homology	NOUN
fnp-3528	309	19	model	model	NOUN
fnp-3528	309	20	has	have	AUX
fnp-3528	309	21	been	be	AUX
fnp-3528	309	22	developed	develop	VERB
fnp-3528	309	23	for	for	ADP
fnp-3528	309	24	molecular	molecular	ADJ
fnp-3528	309	25	docking	docking	NOUN
fnp-3528	309	26	experiments.475	experiments.475	PRON
fnp-3528	309	27	molecular	molecular	ADJ
fnp-3528	309	28	docking	docking	NOUN
fnp-3528	309	29	is	be	AUX
fnp-3528	309	30	a	a	DET
fnp-3528	309	31	very	very	ADV
fnp-3528	309	32	popular	popular	ADJ
fnp-3528	309	33	method	method	NOUN
fnp-3528	309	34	for	for	ADP
fnp-3528	309	35	predicting	predict	VERB
fnp-3528	309	36	binding	bind	VERB
fnp-3528	309	37	orientations	orientation	NOUN
fnp-3528	309	38	or	or	CCONJ
fnp-3528	309	39	poses	pose	NOUN
fnp-3528	309	40	of	of	ADP
fnp-3528	309	41	small	small	ADJ
fnp-3528	309	42	-	-	PUNCT
fnp-3528	309	43	molecules	molecule	NOUN
fnp-3528	309	44	within	within	ADP
fnp-3528	309	45	the	the	DET
fnp-3528	309	46	transporter	transporter	NOUN
fnp-3528	309	47	.	.	PUNCT
fnp-3528	310	1	most	most	ADV
fnp-3528	310	2	often	often	ADV
fnp-3528	310	3	,	,	PUNCT
fnp-3528	310	4	the	the	DET
fnp-3528	310	5	docking	docking	NOUN
fnp-3528	310	6	programs	program	NOUN
fnp-3528	310	7	account	account	VERB
fnp-3528	310	8	for	for	ADP
fnp-3528	310	9	full	full	ADJ
fnp-3528	310	10	conformational	conformational	ADJ
fnp-3528	310	11	flexibility	flexibility	NOUN
fnp-3528	310	12	of	of	ADP
fnp-3528	310	13	ligands	ligand	NOUN
fnp-3528	310	14	within	within	ADP
fnp-3528	310	15	the	the	DET
fnp-3528	310	16	binding	bind	VERB
fnp-3528	310	17	site	site	NOUN
fnp-3528	310	18	,	,	PUNCT
fnp-3528	310	19	treating	treat	VERB
fnp-3528	310	20	the	the	DET
fnp-3528	310	21	protein	protein	NOUN
fnp-3528	310	22	as	as	ADP
fnp-3528	310	23	a	a	DET
fnp-3528	310	24	rigid	rigid	ADJ
fnp-3528	310	25	body	body	NOUN
fnp-3528	310	26	.	.	PUNCT
fnp-3528	311	1	binding	bind	VERB
fnp-3528	311	2	site	site	NOUN
fnp-3528	311	3	identification	identification	NOUN
fnp-3528	311	4	is	be	AUX
fnp-3528	311	5	an	an	DET
fnp-3528	311	6	important	important	ADJ
fnp-3528	311	7	prerequisite	prerequisite	NOUN
fnp-3528	311	8	in	in	ADP
fnp-3528	311	9	the	the	DET
fnp-3528	311	10	structure	structure	NOUN
fnp-3528	311	11	-	-	PUNCT
fnp-3528	311	12	based	base	VERB
fnp-3528	311	13	drug	drug	NOUN
fnp-3528	311	14	design	design	NOUN
fnp-3528	311	15	implementation	implementation	NOUN
fnp-3528	311	16	.	.	PUNCT
fnp-3528	312	1	in	in	ADP
fnp-3528	312	2	terms	term	NOUN
fnp-3528	312	3	of	of	ADP
fnp-3528	312	4	abc	abc	PROPN
fnp-3528	312	5	transporters	transporter	NOUN
fnp-3528	312	6	,	,	PUNCT
fnp-3528	312	7	the	the	DET
fnp-3528	312	8	search	search	NOUN
fnp-3528	312	9	for	for	ADP
fnp-3528	312	10	binding	bind	VERB
fnp-3528	312	11	hot	hot	ADJ
fnp-3528	312	12	spots	spot	NOUN
fnp-3528	312	13	and	and	CCONJ
fnp-3528	312	14	cavities	cavity	NOUN
fnp-3528	312	15	on	on	ADP
fnp-3528	312	16	the	the	DET
fnp-3528	312	17	entire	entire	ADJ
fnp-3528	312	18	volume	volume	NOUN
fnp-3528	312	19	of	of	ADP
fnp-3528	312	20	the	the	DET
fnp-3528	312	21	protein	protein	NOUN
fnp-3528	312	22	(	(	PUNCT
fnp-3528	312	23	e.g.	e.g.	ADV
fnp-3528	312	24	,	,	PUNCT
fnp-3528	312	25	through	through	ADP
fnp-3528	312	26	blind	blind	ADJ
fnp-3528	312	27	docking	docking	NOUN
fnp-3528	312	28	)	)	PUNCT
fnp-3528	312	29	is	be	AUX
fnp-3528	312	30	necessary	necessary	ADJ
fnp-3528	312	31	due	due	ADP
fnp-3528	312	32	to	to	ADP
fnp-3528	312	33	the	the	DET
fnp-3528	312	34	general	general	ADJ
fnp-3528	312	35	lack	lack	NOUN
fnp-3528	312	36	of	of	ADP
fnp-3528	312	37	information	information	NOUN
fnp-3528	312	38	on	on	ADP
fnp-3528	312	39	binding	bind	VERB
fnp-3528	312	40	sites	site	NOUN
fnp-3528	312	41	of	of	ADP
fnp-3528	312	42	abc	abc	PROPN
fnp-3528	312	43	transporters	transporter	NOUN
fnp-3528	312	44	.	.	PUNCT
fnp-3528	313	1	recently	recently	ADV
fnp-3528	313	2	,	,	PUNCT
fnp-3528	313	3	in	in	ADP
fnp-3528	313	4	search	search	NOUN
fnp-3528	313	5	of	of	ADP
fnp-3528	313	6	highly	highly	ADV
fnp-3528	313	7	effective	effective	ADJ
fnp-3528	313	8	modulators	modulator	NOUN
fnp-3528	313	9	addressing	address	VERB
fnp-3528	313	10	abcg2	abcg2	NOUN
fnp-3528	313	11	-	-	PUNCT
fnp-3528	313	12	mediated	mediate	VERB
fnp-3528	313	13	mdr	mdr	NOUN
fnp-3528	313	14	,	,	PUNCT
fnp-3528	313	15	derivatives	derivative	NOUN
fnp-3528	313	16	of	of	ADP
fnp-3528	313	17	quinazolines	quinazoline	NOUN
fnp-3528	313	18	were	be	AUX
fnp-3528	313	19	synthesized	synthesize	VERB
fnp-3528	313	20	and	and	CCONJ
fnp-3528	313	21	biologically	biologically	ADV
fnp-3528	313	22	assessed	assess	VERB
fnp-3528	313	23	using	use	VERB
fnp-3528	313	24	a	a	DET
fnp-3528	313	25	hoechst	hoechst	ADJ
fnp-3528	313	26	33342	33342	NUM
fnp-3528	313	27	accumulation	accumulation	NOUN
fnp-3528	313	28	assay.480	assay.480	NOUN
fnp-3528	313	29	by	by	ADP
fnp-3528	313	30	utilizing	utilize	VERB
fnp-3528	313	31	the	the	DET
fnp-3528	313	32	cryo	cryo	NOUN
fnp-3528	313	33	-	-	PUNCT
fnp-3528	313	34	em	em	PRON
fnp-3528	313	35	structure	structure	NOUN
fnp-3528	313	36	of	of	ADP
fnp-3528	313	37	abcg2,481	abcg2,481	PROPN
fnp-3528	313	38	molecular	molecular	ADJ
fnp-3528	313	39	docking	docking	NOUN
fnp-3528	313	40	studies	study	NOUN
fnp-3528	313	41	were	be	AUX
fnp-3528	313	42	performed	perform	VERB
fnp-3528	313	43	using	use	VERB
fnp-3528	313	44	a	a	DET
fnp-3528	313	45	fragment	fragment	NOUN
fnp-3528	313	46	-	-	PUNCT
fnp-3528	313	47	based	base	VERB
fnp-3528	313	48	approach.482	approach.482	PROPN
fnp-3528	313	49	this	this	DET
fnp-3528	313	50	approach	approach	NOUN
fnp-3528	313	51	was	be	AUX
fnp-3528	313	52	used	use	VERB
fnp-3528	313	53	to	to	PART
fnp-3528	313	54	gain	gain	VERB
fnp-3528	313	55	insights	insight	NOUN
fnp-3528	313	56	into	into	ADP
fnp-3528	313	57	the	the	DET
fnp-3528	313	58	molecular	molecular	ADJ
fnp-3528	313	59	determinants	determinant	NOUN
fnp-3528	313	60	involved	involve	VERB
fnp-3528	313	61	in	in	ADP
fnp-3528	313	62	the	the	DET
fnp-3528	313	63	formation	formation	NOUN
fnp-3528	313	64	of	of	ADP
fnp-3528	313	65	the	the	DET
fnp-3528	313	66	transporter	transporter	NOUN
fnp-3528	313	67	-	-	PUNCT
fnp-3528	313	68	substrate	substrate	NOUN
fnp-3528	313	69	complex.480	complex.480	NOUN
fnp-3528	313	70	based	base	VERB
fnp-3528	313	71	on	on	ADP
fnp-3528	313	72	the	the	DET
fnp-3528	313	73	docking	docking	NOUN
fnp-3528	313	74	studies	study	NOUN
fnp-3528	313	75	,	,	PUNCT
fnp-3528	313	76	the	the	DET
fnp-3528	313	77	putative	putative	ADJ
fnp-3528	313	78	binding	bind	VERB
fnp-3528	313	79	site	site	NOUN
fnp-3528	313	80	of	of	ADP
fnp-3528	313	81	the	the	DET
fnp-3528	313	82	abcg2	abcg2	NOUN
fnp-3528	313	83	substrate	substrate	NOUN
fnp-3528	313	84	,	,	PUNCT
fnp-3528	313	85	hoechst	hoechst	NOUN
fnp-3528	313	86	33342	33342	NUM
fnp-3528	313	87	,	,	PUNCT
fnp-3528	313	88	and	and	CCONJ
fnp-3528	313	89	its	its	PRON
fnp-3528	313	90	interaction	interaction	NOUN
fnp-3528	313	91	with	with	ADP
fnp-3528	313	92	the	the	DET
fnp-3528	313	93	amino	amino	NOUN
fnp-3528	313	94	acids	acid	NOUN
fnp-3528	313	95	in	in	ADP
fnp-3528	313	96	the	the	DET
fnp-3528	313	97	binding	bind	VERB
fnp-3528	313	98	pocket	pocket	NOUN
fnp-3528	313	99	was	be	AUX
fnp-3528	313	100	proposed.480	proposed.480	PROPN
fnp-3528	313	101	the	the	DET
fnp-3528	313	102	predicted	predict	VERB
fnp-3528	313	103	binding	bind	VERB
fnp-3528	313	104	pose	pose	NOUN
fnp-3528	313	105	was	be	AUX
fnp-3528	313	106	rationalized	rationalize	VERB
fnp-3528	313	107	based	base	VERB
fnp-3528	313	108	on	on	ADP
fnp-3528	313	109	the	the	DET
fnp-3528	313	110	mutagenesis	mutagenesis	NOUN
fnp-3528	313	111	data	datum	NOUN
fnp-3528	313	112	reported	report	VERB
fnp-3528	313	113	in	in	ADP
fnp-3528	313	114	the	the	DET
fnp-3528	313	115	literature483	literature483	PROPN
fnp-3528	313	116	-	-	PUNCT
fnp-3528	313	117	487	487	NUM
fnp-3528	313	118	and	and	CCONJ
fnp-3528	313	119	further	far	ADV
fnp-3528	313	120	confirmed	confirm	VERB
fnp-3528	313	121	with	with	ADP
fnp-3528	313	122	kinetic	kinetic	ADJ
fnp-3528	313	123	studies	study	NOUN
fnp-3528	313	124	to	to	PART
fnp-3528	313	125	determine	determine	VERB
fnp-3528	313	126	the	the	DET
fnp-3528	313	127	mode	mode	NOUN
fnp-3528	313	128	of	of	ADP
fnp-3528	313	129	inhibition.480	inhibition.480	NOUN
fnp-3528	313	130	this	this	DET
fnp-3528	313	131	subsequent	subsequent	ADJ
fnp-3528	313	132	structure	structure	NOUN
fnp-3528	313	133	-	-	PUNCT
fnp-3528	313	134	based	base	VERB
fnp-3528	313	135	approach	approach	NOUN
fnp-3528	313	136	led	lead	VERB
fnp-3528	313	137	to	to	ADP
fnp-3528	313	138	the	the	DET
fnp-3528	313	139	discovery	discovery	NOUN
fnp-3528	313	140	of	of	ADP
fnp-3528	313	141	highly	highly	ADV
fnp-3528	313	142	potent	potent	ADJ
fnp-3528	313	143	pyrimidine	pyrimidine	NOUN
fnp-3528	313	144	-	-	PUNCT
fnp-3528	313	145	based	base	VERB
fnp-3528	313	146	abcg2	abcg2	NOUN
fnp-3528	313	147	inhibitors,488,489	inhibitors,488,489	NOUN
fnp-3528	313	148	specifically	specifically	ADV
fnp-3528	313	149	by	by	ADP
fnp-3528	313	150	identifying	identify	VERB
fnp-3528	313	151	a	a	DET
fnp-3528	313	152	novel	novel	ADJ
fnp-3528	313	153	binding	bind	VERB
fnp-3528	313	154	pocket	pocket	NOUN
fnp-3528	313	155	of	of	ADP
fnp-3528	313	156	this	this	DET
fnp-3528	313	157	transporter.488	transporter.488	NUM
fnp-3528	313	158	in	in	ADP
fnp-3528	313	159	terms	term	NOUN
fnp-3528	313	160	of	of	ADP
fnp-3528	313	161	abca	abca	NOUN
fnp-3528	313	162	transporters	transporter	NOUN
fnp-3528	313	163	,	,	PUNCT
fnp-3528	313	164	molecular	molecular	ADJ
fnp-3528	313	165	docking	docking	NOUN
fnp-3528	313	166	experiments	experiment	NOUN
fnp-3528	313	167	with	with	ADP
fnp-3528	313	168	the	the	DET
fnp-3528	313	169	newly	newly	ADV
fnp-3528	313	170	derived	derive	VERB
fnp-3528	313	171	abca7	abca7	PROPN
fnp-3528	313	172	homology	homology	NOUN
fnp-3528	313	173	model	model	NOUN
fnp-3528	313	174	applying	apply	VERB
fnp-3528	313	175	a	a	DET
fnp-3528	313	176	set	set	NOUN
fnp-3528	313	177	of	of	ADP
fnp-3528	313	178	diverse	diverse	ADJ
fnp-3528	313	179	pan	pan	NOUN
fnp-3528	313	180	-	-	ADJ
fnp-3528	313	181	abc	abc	ADJ
fnp-3528	313	182	transporter	transporter	NOUN
fnp-3528	313	183	inhibitors	inhibitor	NOUN
fnp-3528	313	184	revealed	reveal	VERB
fnp-3528	313	185	a	a	DET
fnp-3528	313	186	putative	putative	ADJ
fnp-3528	313	187	common	common	ADJ
fnp-3528	313	188	‘	'	PUNCT
fnp-3528	313	189	multitarget	multitarget	ADJ
fnp-3528	313	190	binding	bind	VERB
fnp-3528	313	191	site	site	NOUN
fnp-3528	313	192	’	'	PUNCT
fnp-3528	313	193	identified	identify	VERB
fnp-3528	313	194	within	within	ADP
fnp-3528	313	195	the	the	DET
fnp-3528	313	196	transmembrane	transmembrane	NOUN
fnp-3528	313	197	domains	domain	NOUN
fnp-3528	313	198	of	of	ADP
fnp-3528	313	199	abca7	abca7	PROPN
fnp-3528	313	200	.	.	PUNCT
fnp-3528	314	1	it	it	PRON
fnp-3528	314	2	must	must	AUX
fnp-3528	314	3	be	be	AUX
fnp-3528	314	4	noted	note	VERB
fnp-3528	314	5	that	that	SCONJ
fnp-3528	314	6	the	the	DET
fnp-3528	314	7	nucleotide	nucleotide	NOUN
fnp-3528	314	8	binding	bind	VERB
fnp-3528	314	9	domains	domain	NOUN
fnp-3528	314	10	are	be	AUX
fnp-3528	314	11	the	the	DET
fnp-3528	314	12	most	most	ADV
fnp-3528	314	13	highly	highly	ADV
fnp-3528	314	14	conserved	conserved	ADJ
fnp-3528	314	15	regions	region	NOUN
fnp-3528	314	16	amongst	amongst	ADP
fnp-3528	314	17	all	all	DET
fnp-3528	314	18	abc	abc	PROPN
fnp-3528	314	19	transporters	transporter	NOUN
fnp-3528	314	20	,	,	PUNCT
fnp-3528	314	21	and	and	CCONJ
fnp-3528	314	22	hence	hence	ADV
fnp-3528	314	23	,	,	PUNCT
fnp-3528	314	24	may	may	AUX
fnp-3528	314	25	also	also	ADV
fnp-3528	314	26	represent	represent	VERB
fnp-3528	314	27	a(nother	a(nother	ADV
fnp-3528	314	28	)	)	PUNCT
fnp-3528	314	29	multitarget	multitarget	PROPN
fnp-3528	314	30	binding	bind	VERB
fnp-3528	314	31	site	site	NOUN
fnp-3528	314	32	for	for	ADP
fnp-3528	314	33	certain	certain	ADJ
fnp-3528	314	34	drugs	drug	NOUN
fnp-3528	314	35	.	.	PUNCT
fnp-3528	315	1	however	however	ADV
fnp-3528	315	2	,	,	PUNCT
fnp-3528	315	3	the	the	DET
fnp-3528	315	4	vast	vast	ADJ
fnp-3528	315	5	majority	majority	NOUN
fnp-3528	315	6	of	of	ADP
fnp-3528	315	7	data	datum	NOUN
fnp-3528	315	8	reported	report	VERB
fnp-3528	315	9	in	in	ADP
fnp-3528	315	10	the	the	DET
fnp-3528	315	11	past	past	ADJ
fnp-3528	315	12	hint	hint	NOUN
fnp-3528	315	13	to	to	ADP
fnp-3528	315	14	the	the	DET
fnp-3528	315	15	transmembrane	transmembrane	NOUN
fnp-3528	315	16	domains	domain	NOUN
fnp-3528	315	17	as	as	ADP
fnp-3528	315	18	the	the	DET
fnp-3528	315	19	actual	actual	ADJ
fnp-3528	315	20	venue	venue	NOUN
fnp-3528	315	21	of	of	ADP
fnp-3528	315	22	bioactivity	bioactivity	NOUN
fnp-3528	315	23	in	in	ADP
fnp-3528	315	24	terms	term	NOUN
fnp-3528	315	25	of	of	ADP
fnp-3528	315	26	abc	abc	PROPN
fnp-3528	315	27	transporter	transporter	NOUN
fnp-3528	315	28	modulation.472	modulation.472	ADJ
fnp-3528	315	29	these	these	DET
fnp-3528	315	30	results	result	NOUN
fnp-3528	315	31	as	as	SCONJ
fnp-3528	315	32	described	describe	VERB
fnp-3528	315	33	above475,480,488,489	above475,480,488,489	NOUN
fnp-3528	315	34	give	give	VERB
fnp-3528	315	35	this	this	DET
fnp-3528	315	36	methodology	methodology	NOUN
fnp-3528	315	37	a	a	DET
fnp-3528	315	38	high	high	ADJ
fnp-3528	315	39	relevance	relevance	NOUN
fnp-3528	315	40	in	in	ADP
fnp-3528	315	41	the	the	DET
fnp-3528	315	42	drug	drug	NOUN
fnp-3528	315	43	development	development	NOUN
fnp-3528	315	44	process	process	NOUN
fnp-3528	315	45	in	in	ADP
fnp-3528	315	46	terms	term	NOUN
fnp-3528	315	47	of	of	ADP
fnp-3528	315	48	novel	novel	ADJ
fnp-3528	315	49	lead	lead	NOUN
fnp-3528	315	50	molecules	molecule	NOUN
fnp-3528	315	51	in	in	ADP
fnp-3528	315	52	general	general	ADJ
fnp-3528	315	53	,	,	PUNCT
fnp-3528	315	54	and	and	CCONJ
fnp-3528	315	55	provide	provide	VERB
fnp-3528	315	56	the	the	DET
fnp-3528	315	57	basis	basis	NOUN
fnp-3528	315	58	for	for	ADP
fnp-3528	315	59	rationally	rationally	ADV
fnp-3528	315	60	designed	design	VERB
fnp-3528	315	61	structure	structure	NOUN
fnp-3528	315	62	-	-	PUNCT
fnp-3528	315	63	guided	guide	VERB
fnp-3528	315	64	approaches	approach	NOUN
fnp-3528	315	65	for	for	ADP
fnp-3528	315	66	the	the	DET
fnp-3528	315	67	identification	identification	NOUN
fnp-3528	315	68	of	of	ADP
fnp-3528	315	69	modulators	modulator	NOUN
fnp-3528	315	70	of	of	ADP
fnp-3528	315	71	abca	abca	NOUN
fnp-3528	315	72	transporters	transporter	NOUN
fnp-3528	315	73	in	in	ADP
fnp-3528	315	74	particular	particular	ADJ
fnp-3528	315	75	,	,	PUNCT
fnp-3528	315	76	as	as	SCONJ
fnp-3528	315	77	recently	recently	ADV
fnp-3528	315	78	demonstrated	demonstrate	VERB
fnp-3528	315	79	for	for	SCONJ
fnp-3528	315	80	abca7.475	abca7.475	PROPN
fnp-3528	315	81	ligand	ligand	NOUN
fnp-3528	315	82	-	-	PUNCT
fnp-3528	315	83	based	base	VERB
fnp-3528	315	84	drug	drug	NOUN
fnp-3528	315	85	design	design	NOUN
fnp-3528	315	86	similarity	similarity	NOUN
fnp-3528	315	87	search	search	VERB
fnp-3528	315	88	the	the	DET
fnp-3528	315	89	analysis	analysis	NOUN
fnp-3528	315	90	of	of	ADP
fnp-3528	315	91	structure	structure	NOUN
fnp-3528	315	92	-	-	PUNCT
fnp-3528	315	93	activity	activity	NOUN
fnp-3528	315	94	relationships	relationship	NOUN
fnp-3528	315	95	using	use	VERB
fnp-3528	315	96	ligand	ligand	NOUN
fnp-3528	315	97	-	-	PUNCT
fnp-3528	315	98	based	base	VERB
fnp-3528	315	99	approaches	approach	NOUN
fnp-3528	315	100	is	be	AUX
fnp-3528	315	101	an	an	DET
fnp-3528	315	102	essential	essential	ADJ
fnp-3528	315	103	component	component	NOUN
fnp-3528	315	104	of	of	ADP
fnp-3528	315	105	medicinal	medicinal	ADJ
fnp-3528	315	106	chemistry	chemistry	NOUN
fnp-3528	315	107	and	and	CCONJ
fnp-3528	315	108	pharmacology	pharmacology	NOUN
fnp-3528	315	109	of	of	ADP
fnp-3528	315	110	abc	abc	PROPN
fnp-3528	315	111	transporters	transporter	NOUN
fnp-3528	315	112	.	.	PUNCT
fnp-3528	316	1	this	this	PRON
fnp-3528	316	2	becomes	become	VERB
fnp-3528	316	3	evident	evident	ADJ
fnp-3528	316	4	as	as	SCONJ
fnp-3528	316	5	x	x	NOUN
fnp-3528	316	6	-	-	NOUN
fnp-3528	316	7	ray	ray	NOUN
fnp-3528	316	8	or	or	CCONJ
fnp-3528	316	9	cryo	cryo	NOUN
fnp-3528	316	10	-	-	PUNCT
fnp-3528	316	11	em	em	PRON
fnp-3528	316	12	structures	structure	NOUN
fnp-3528	316	13	of	of	ADP
fnp-3528	316	14	most	most	ADJ
fnp-3528	316	15	abc	abc	PROPN
fnp-3528	316	16	transporter	transporter	NOUN
fnp-3528	316	17	subtypes	subtype	NOUN
fnp-3528	316	18	are	be	AUX
fnp-3528	316	19	lacking	lack	VERB
fnp-3528	316	20	to	to	PART
fnp-3528	316	21	serve	serve	VERB
fnp-3528	316	22	as	as	ADP
fnp-3528	316	23	suitable	suitable	ADJ
fnp-3528	316	24	templates	template	NOUN
fnp-3528	316	25	with	with	ADP
fnp-3528	316	26	sufficient	sufficient	ADJ
fnp-3528	316	27	similarity	similarity	NOUN
fnp-3528	316	28	for	for	ADP
fnp-3528	316	29	generating	generate	VERB
fnp-3528	316	30	homology	homology	NOUN
fnp-3528	316	31	models	model	NOUN
fnp-3528	316	32	.	.	PUNCT
fnp-3528	317	1	ligand	ligand	NOUN
fnp-3528	317	2	-	-	PUNCT
fnp-3528	317	3	based	base	VERB
fnp-3528	317	4	approaches	approach	NOUN
fnp-3528	317	5	establish	establish	VERB
fnp-3528	317	6	a	a	DET
fnp-3528	317	7	correlation	correlation	NOUN
fnp-3528	317	8	between	between	ADP
fnp-3528	317	9	the	the	DET
fnp-3528	317	10	molecular	molecular	ADJ
fnp-3528	317	11	structure	structure	NOUN
fnp-3528	317	12	of	of	ADP
fnp-3528	317	13	a	a	DET
fnp-3528	317	14	small	small	ADJ
fnp-3528	317	15	-	-	PUNCT
fnp-3528	317	16	molecule	molecule	NOUN
fnp-3528	317	17	and	and	CCONJ
fnp-3528	317	18	the	the	DET
fnp-3528	317	19	triggered	triggered	ADJ
fnp-3528	317	20	biological	biological	ADJ
fnp-3528	317	21	response	response	NOUN
fnp-3528	317	22	of	of	ADP
fnp-3528	317	23	the	the	DET
fnp-3528	317	24	target	target	NOUN
fnp-3528	317	25	.	.	PUNCT
fnp-3528	318	1	the	the	DET
fnp-3528	318	2	chemical	chemical	NOUN
fnp-3528	318	3	representation	representation	NOUN
fnp-3528	318	4	of	of	ADP
fnp-3528	318	5	the	the	DET
fnp-3528	318	6	molecules	molecule	NOUN
fnp-3528	318	7	is	be	AUX
fnp-3528	318	8	often	often	ADV
fnp-3528	318	9	expressed	express	VERB
fnp-3528	318	10	using	use	VERB
fnp-3528	318	11	descriptors	descriptor	NOUN
fnp-3528	318	12	,	,	PUNCT
fnp-3528	318	13	which	which	PRON
fnp-3528	318	14	are	be	AUX
fnp-3528	318	15	attributes	attribute	NOUN
fnp-3528	318	16	that	that	PRON
fnp-3528	318	17	conserve	conserve	VERB
fnp-3528	318	18	the	the	DET
fnp-3528	318	19	physicochemical	physicochemical	ADJ
fnp-3528	318	20	information	information	NOUN
fnp-3528	318	21	of	of	ADP
fnp-3528	318	22	the	the	DET
fnp-3528	318	23	molecule	molecule	NOUN
fnp-3528	318	24	.	.	PUNCT
fnp-3528	319	1	these	these	DET
fnp-3528	319	2	descriptors	descriptor	NOUN
fnp-3528	319	3	refer	refer	VERB
fnp-3528	319	4	to	to	ADP
fnp-3528	319	5	generic	generic	ADJ
fnp-3528	319	6	properties	property	NOUN
fnp-3528	319	7	such	such	ADJ
fnp-3528	319	8	as	as	ADP
fnp-3528	319	9	logp	logp	NOUN
fnp-3528	319	10	,	,	PUNCT
fnp-3528	319	11	molecular	molecular	ADJ
fnp-3528	319	12	weight	weight	NOUN
fnp-3528	319	13	,	,	PUNCT
fnp-3528	319	14	polar	polar	ADJ
fnp-3528	319	15	surface	surface	NOUN
fnp-3528	319	16	area	area	NOUN
fnp-3528	319	17	,	,	PUNCT
fnp-3528	319	18	rotatable	rotatable	ADJ
fnp-3528	319	19	bonds	bond	NOUN
fnp-3528	319	20	,	,	PUNCT
fnp-3528	319	21	or	or	CCONJ
fnp-3528	319	22	molar	molar	ADJ
fnp-3528	319	23	refractivity	refractivity	NOUN
fnp-3528	319	24	.	.	PUNCT
fnp-3528	320	1	alternatively	alternatively	ADV
fnp-3528	320	2	,	,	PUNCT
fnp-3528	320	3	structural	structural	ADJ
fnp-3528	320	4	representations	representation	NOUN
fnp-3528	320	5	of	of	ADP
fnp-3528	320	6	the	the	DET
fnp-3528	320	7	molecules	molecule	NOUN
fnp-3528	320	8	can	can	AUX
fnp-3528	320	9	form	form	VERB
fnp-3528	320	10	fingerprints	fingerprint	NOUN
fnp-3528	320	11	that	that	PRON
fnp-3528	320	12	portray	portray	VERB
fnp-3528	320	13	existent	existent	ADJ
fnp-3528	320	14	molecular	molecular	ADJ
fnp-3528	320	15	features	feature	NOUN
fnp-3528	320	16	of	of	ADP
fnp-3528	320	17	the	the	DET
fnp-3528	320	18	molecule	molecule	NOUN
fnp-3528	320	19	in	in	ADP
fnp-3528	320	20	a	a	DET
fnp-3528	320	21	binary	binary	PROPN
fnp-3528	320	22	code	code	NOUN
fnp-3528	320	23	.	.	PUNCT
fnp-3528	321	1	these	these	DET
fnp-3528	321	2	fingerprints	fingerprint	NOUN
fnp-3528	321	3	are	be	AUX
fnp-3528	321	4	,	,	PUNCT
fnp-3528	321	5	for	for	ADP
fnp-3528	321	6	example	example	NOUN
fnp-3528	321	7	,	,	PUNCT
fnp-3528	321	8	path	path	NOUN
fnp-3528	321	9	-	-	PUNCT
fnp-3528	321	10	like,490	like,490	NOUN
fnp-3528	321	11	or	or	CCONJ
fnp-3528	321	12	circular	circular	ADJ
fnp-3528	321	13	-	-	PUNCT
fnp-3528	321	14	based,491,492	based,491,492	NOUN
fnp-3528	321	15	such	such	ADJ
fnp-3528	321	16	as	as	ADP
fnp-3528	321	17	maccs	maccs	NOUN
fnp-3528	321	18	or	or	CCONJ
fnp-3528	321	19	ecfp4	ecfp4	PROPN
fnp-3528	321	20	,	,	PUNCT
fnp-3528	321	21	respectively	respectively	ADV
fnp-3528	321	22	.	.	PUNCT
fnp-3528	322	1	utilizing	utilize	VERB
fnp-3528	322	2	these	these	DET
fnp-3528	322	3	representations	representation	NOUN
fnp-3528	322	4	of	of	ADP
fnp-3528	322	5	molecules	molecule	NOUN
fnp-3528	322	6	,	,	PUNCT
fnp-3528	322	7	similarity	similarity	NOUN
fnp-3528	322	8	-	-	PUNCT
fnp-3528	322	9	driven	drive	VERB
fnp-3528	322	10	virtual	virtual	ADJ
fnp-3528	322	11	screenings	screening	NOUN
fnp-3528	322	12	can	can	AUX
fnp-3528	322	13	be	be	AUX
fnp-3528	322	14	applied	apply	VERB
fnp-3528	322	15	.	.	PUNCT
fnp-3528	323	1	here	here	ADV
fnp-3528	323	2	,	,	PUNCT
fnp-3528	323	3	molecules	molecule	NOUN
fnp-3528	323	4	are	be	AUX
fnp-3528	323	5	extracted	extract	VERB
fnp-3528	323	6	from	from	ADP
fnp-3528	323	7	a	a	DET
fnp-3528	323	8	virtual	virtual	ADJ
fnp-3528	323	9	library	library	NOUN
fnp-3528	323	10	of	of	ADP
fnp-3528	323	11	millions	million	NOUN
fnp-3528	323	12	or	or	CCONJ
fnp-3528	323	13	billions	billion	NOUN
fnp-3528	323	14	of	of	ADP
fnp-3528	323	15	compounds	compound	NOUN
fnp-3528	323	16	compared	compare	VERB
fnp-3528	323	17	to	to	ADP
fnp-3528	323	18	the	the	DET
fnp-3528	323	19	bioactive	bioactive	NOUN
fnp-3528	323	20	template	template	NOUN
fnp-3528	323	21	molecule(s	molecule(s	NOUN
fnp-3528	323	22	)	)	PUNCT
fnp-3528	323	23	according	accord	VERB
fnp-3528	323	24	to	to	ADP
fnp-3528	323	25	the	the	DET
fnp-3528	323	26	similarity	similarity	NOUN
fnp-3528	323	27	principle	principle	NOUN
fnp-3528	323	28	.	.	PUNCT
fnp-3528	324	1	the	the	DET
fnp-3528	324	2	abstract	abstract	ADJ
fnp-3528	324	3	representation	representation	NOUN
fnp-3528	324	4	of	of	ADP
fnp-3528	324	5	molecules	molecule	NOUN
fnp-3528	324	6	enables	enable	VERB
fnp-3528	324	7	clustering	clustering	NOUN
fnp-3528	324	8	of	of	ADP
fnp-3528	324	9	compounds	compound	NOUN
fnp-3528	324	10	,	,	PUNCT
fnp-3528	324	11	which	which	PRON
fnp-3528	324	12	is	be	AUX
fnp-3528	324	13	a	a	DET
fnp-3528	324	14	methodology	methodology	NOUN
fnp-3528	324	15	to	to	PART
fnp-3528	324	16	categorize	categorize	VERB
fnp-3528	324	17	a	a	DET
fnp-3528	324	18	diverse	diverse	ADJ
fnp-3528	324	19	set	set	NOUN
fnp-3528	324	20	of	of	ADP
fnp-3528	324	21	molecules	molecule	NOUN
fnp-3528	324	22	.	.	PUNCT
fnp-3528	325	1	moreover	moreover	ADV
fnp-3528	325	2	,	,	PUNCT
fnp-3528	325	3	these	these	DET
fnp-3528	325	4	abstract	abstract	ADJ
fnp-3528	325	5	representations	representation	NOUN
fnp-3528	325	6	can	can	AUX
fnp-3528	325	7	be	be	AUX
fnp-3528	325	8	used	use	VERB
fnp-3528	325	9	in	in	ADP
fnp-3528	325	10	different	different	ADJ
fnp-3528	325	11	machine	machine	NOUN
fnp-3528	325	12	learning	learning	NOUN
fnp-3528	325	13	(	(	PUNCT
fnp-3528	325	14	artificial	artificial	ADJ
fnp-3528	325	15	intelligence	intelligence	NOUN
fnp-3528	325	16	)	)	PUNCT
fnp-3528	325	17	approaches	approach	NOUN
fnp-3528	325	18	.	.	PUNCT
fnp-3528	326	1	pharmacophore	pharmacophore	NOUN
fnp-3528	326	2	modelling	model	VERB
fnp-3528	326	3	another	another	DET
fnp-3528	326	4	common	common	ADJ
fnp-3528	326	5	approach	approach	NOUN
fnp-3528	326	6	is	be	AUX
fnp-3528	326	7	pharmacophore	pharmacophore	NOUN
fnp-3528	326	8	modelling	modelling	NOUN
fnp-3528	326	9	,	,	PUNCT
fnp-3528	326	10	which	which	PRON
fnp-3528	326	11	analyzes	analyze	VERB
fnp-3528	326	12	a	a	DET
fnp-3528	326	13	number	number	NOUN
fnp-3528	326	14	of	of	ADP
fnp-3528	326	15	ligands	ligand	NOUN
fnp-3528	326	16	with	with	ADP
fnp-3528	326	17	a	a	DET
fnp-3528	326	18	common	common	ADJ
fnp-3528	326	19	mechanism	mechanism	NOUN
fnp-3528	326	20	of	of	ADP
fnp-3528	326	21	action	action	NOUN
fnp-3528	326	22	.	.	PUNCT
fnp-3528	327	1	the	the	DET
fnp-3528	327	2	model	model	NOUN
fnp-3528	327	3	is	be	AUX
fnp-3528	327	4	the	the	DET
fnp-3528	327	5	ensemble	ensemble	ADJ
fnp-3528	327	6	of	of	ADP
fnp-3528	327	7	common	common	ADJ
fnp-3528	327	8	chemical	chemical	NOUN
fnp-3528	327	9	features	feature	NOUN
fnp-3528	327	10	that	that	PRON
fnp-3528	327	11	are	be	AUX
fnp-3528	327	12	required	require	VERB
fnp-3528	327	13	to	to	PART
fnp-3528	327	14	ensure	ensure	VERB
fnp-3528	327	15	the	the	DET
fnp-3528	327	16	molecular	molecular	ADJ
fnp-3528	327	17	interaction	interaction	NOUN
fnp-3528	327	18	of	of	ADP
fnp-3528	327	19	the	the	DET
fnp-3528	327	20	ligands	ligand	NOUN
fnp-3528	327	21	with	with	ADP
fnp-3528	327	22	the	the	DET
fnp-3528	327	23	target	target	NOUN
fnp-3528	327	24	,	,	PUNCT
fnp-3528	327	25	such	such	ADJ
fnp-3528	327	26	as	as	ADP
fnp-3528	327	27	hydrogen	hydrogen	NOUN
fnp-3528	327	28	bond	bond	NOUN
fnp-3528	327	29	donors	donor	NOUN
fnp-3528	327	30	and	and	CCONJ
fnp-3528	327	31	acceptors	acceptor	NOUN
fnp-3528	327	32	as	as	ADV
fnp-3528	327	33	well	well	ADV
fnp-3528	327	34	as	as	ADP
fnp-3528	327	35	aromatic	aromatic	ADJ
fnp-3528	327	36	and	and	CCONJ
fnp-3528	327	37	hydrophobic	hydrophobic	NOUN
fnp-3528	327	38	centers	center	NOUN
fnp-3528	327	39	.	.	PUNCT
fnp-3528	328	1	the	the	DET
fnp-3528	328	2	pharmacophore	pharmacophore	NOUN
fnp-3528	328	3	models	model	NOUN
fnp-3528	328	4	are	be	AUX
fnp-3528	328	5	generated	generate	VERB
fnp-3528	328	6	by	by	ADP
fnp-3528	328	7	extracting	extract	VERB
fnp-3528	328	8	common	common	ADJ
fnp-3528	328	9	molecular	molecular	ADJ
fnp-3528	328	10	features	feature	NOUN
fnp-3528	328	11	through	through	ADP
fnp-3528	328	12	flexible	flexible	ADJ
fnp-3528	328	13	alignment	alignment	NOUN
fnp-3528	328	14	of	of	ADP
fnp-3528	328	15	the	the	DET
fnp-3528	328	16	active	active	ADJ
fnp-3528	328	17	biomolecules.493,494	biomolecules.493,494	NOUN
fnp-3528	328	18	this	this	PRON
fnp-3528	328	19	can	can	AUX
fnp-3528	328	20	be	be	AUX
fnp-3528	328	21	achieved	achieve	VERB
fnp-3528	328	22	by	by	ADP
fnp-3528	328	23	generating	generate	VERB
fnp-3528	328	24	all	all	DET
fnp-3528	328	25	possible	possible	ADJ
fnp-3528	328	26	conformations	conformation	NOUN
fnp-3528	328	27	of	of	ADP
fnp-3528	328	28	the	the	DET
fnp-3528	328	29	ligand	ligand	NOUN
fnp-3528	328	30	and	and	CCONJ
fnp-3528	328	31	aligning	align	VERB
fnp-3528	328	32	them	they	PRON
fnp-3528	328	33	to	to	PART
fnp-3528	328	34	determine	determine	VERB
fnp-3528	328	35	the	the	DET
fnp-3528	328	36	essential	essential	ADJ
fnp-3528	328	37	chemical	chemical	NOUN
fnp-3528	328	38	features	feature	NOUN
fnp-3528	328	39	and	and	CCONJ
fnp-3528	328	40	molecular	molecular	ADJ
fnp-3528	328	41	orientation	orientation	NOUN
fnp-3528	328	42	to	to	PART
fnp-3528	328	43	construct	construct	VERB
fnp-3528	328	44	the	the	DET
fnp-3528	328	45	pharmacophore	pharmacophore	NOUN
fnp-3528	328	46	model	model	NOUN
fnp-3528	328	47	.	.	PUNCT
fnp-3528	329	1	the	the	DET
fnp-3528	329	2	conformational	conformational	ADJ
fnp-3528	329	3	flexibility	flexibility	NOUN
fnp-3528	329	4	of	of	ADP
fnp-3528	329	5	the	the	DET
fnp-3528	329	6	ligands	ligand	NOUN
fnp-3528	329	7	representing	represent	VERB
fnp-3528	329	8	the	the	DET
fnp-3528	329	9	chemical	chemical	NOUN
fnp-3528	329	10	features	feature	NOUN
fnp-3528	329	11	is	be	AUX
fnp-3528	329	12	the	the	DET
fnp-3528	329	13	key	key	ADJ
fnp-3528	329	14	factor	factor	NOUN
fnp-3528	329	15	in	in	ADP
fnp-3528	329	16	the	the	DET
fnp-3528	329	17	pharmacophore	pharmacophore	NOUN
fnp-3528	329	18	model	model	NOUN
fnp-3528	329	19	generation	generation	NOUN
fnp-3528	329	20	.	.	PUNCT
fnp-3528	330	1	pattern	pattern	NOUN
fnp-3528	330	2	analysis	analysis	NOUN
fnp-3528	330	3	in	in	ADP
fnp-3528	330	4	addition	addition	NOUN
fnp-3528	330	5	to	to	ADP
fnp-3528	330	6	these	these	DET
fnp-3528	330	7	classical	classical	ADJ
fnp-3528	330	8	computational	computational	ADJ
fnp-3528	330	9	approaches	approach	NOUN
fnp-3528	330	10	,	,	PUNCT
fnp-3528	330	11	similarity	similarity	NOUN
fnp-3528	330	12	search	search	NOUN
fnp-3528	330	13	and	and	CCONJ
fnp-3528	330	14	pharmacophore	pharmacophore	NOUN
fnp-3528	330	15	modelling	modelling	NOUN
fnp-3528	330	16	,	,	PUNCT
fnp-3528	330	17	a	a	DET
fnp-3528	330	18	pattern	pattern	NOUN
fnp-3528	330	19	analysis	analysis	NOUN
fnp-3528	330	20	approach	approach	NOUN
fnp-3528	330	21	(	(	PUNCT
fnp-3528	330	22	‘	'	PUNCT
fnp-3528	330	23	c@pa	c@pa	NOUN
fnp-3528	330	24	’	'	PUNCT
fnp-3528	330	25	=	=	SYM
fnp-3528	330	26	computer	computer	NOUN
fnp-3528	330	27	-	-	PUNCT
fnp-3528	330	28	aided	aid	VERB
fnp-3528	330	29	pattern	pattern	NOUN
fnp-3528	330	30	analysis	analysis	NOUN
fnp-3528	330	31	’	'	PUNCT
fnp-3528	330	32	)	)	PUNCT
fnp-3528	330	33	has	have	AUX
fnp-3528	330	34	been	be	AUX
fnp-3528	330	35	reported	report	VERB
fnp-3528	330	36	recently.18,19,495	recently.18,19,495	ADJ
fnp-3528	330	37	pattern	pattern	NOUN
fnp-3528	330	38	analysis	analysis	NOUN
fnp-3528	330	39	extracts	extract	NOUN
fnp-3528	330	40	both	both	DET
fnp-3528	330	41	basic	basic	ADJ
fnp-3528	330	42	scaffolds	scaffold	NOUN
fnp-3528	330	43	and	and	CCONJ
fnp-3528	330	44	the	the	DET
fnp-3528	330	45	statistical	statistical	ADJ
fnp-3528	330	46	distribution	distribution	NOUN
fnp-3528	330	47	of	of	ADP
fnp-3528	330	48	substructural	substructural	ADJ
fnp-3528	330	49	elements	element	NOUN
fnp-3528	330	50	amongst	amongst	ADP
fnp-3528	330	51	the	the	DET
fnp-3528	330	52	template	template	NOUN
fnp-3528	330	53	ligands	ligand	NOUN
fnp-3528	330	54	.	.	PUNCT
fnp-3528	331	1	it	it	PRON
fnp-3528	331	2	works	work	VERB
fnp-3528	331	3	similarly	similarly	ADV
fnp-3528	331	4	to	to	ADP
fnp-3528	331	5	non	non	ADJ
fnp-3528	331	6	-	-	ADJ
fnp-3528	331	7	physicochemical	physicochemical	ADJ
fnp-3528	331	8	properties	property	NOUN
fnp-3528	331	9	-	-	PUNCT
fnp-3528	331	10	related	relate	VERB
fnp-3528	331	11	fingerprints	fingerprint	NOUN
fnp-3528	331	12	and	and	CCONJ
fnp-3528	331	13	conserves	conserve	NOUN
fnp-3528	331	14	substructural	substructural	ADJ
fnp-3528	331	15	features	feature	NOUN
fnp-3528	331	16	as	as	SCONJ
fnp-3528	331	17	they	they	PRON
fnp-3528	331	18	are	be	AUX
fnp-3528	331	19	present	present	ADJ
fnp-3528	331	20	in	in	ADP
fnp-3528	331	21	the	the	DET
fnp-3528	331	22	molecules	molecule	NOUN
fnp-3528	331	23	.	.	PUNCT
fnp-3528	332	1	pattern	pattern	NOUN
fnp-3528	332	2	analysis	analysis	NOUN
fnp-3528	332	3	has	have	AUX
fnp-3528	332	4	specifically	specifically	ADV
fnp-3528	332	5	been	be	AUX
fnp-3528	332	6	derived	derive	VERB
fnp-3528	332	7	for	for	ADP
fnp-3528	332	8	the	the	DET
fnp-3528	332	9	development	development	NOUN
fnp-3528	332	10	of	of	ADP
fnp-3528	332	11	novel	novel	ADJ
fnp-3528	332	12	potent	potent	NOUN
fnp-3528	332	13	multitarget	multitarget	PROPN
fnp-3528	332	14	abc	abc	PROPN
fnp-3528	332	15	transporter	transporter	NOUN
fnp-3528	332	16	inhibitors	inhibitor	NOUN
fnp-3528	332	17	.	.	PUNCT
fnp-3528	333	1	the	the	DET
fnp-3528	333	2	basic	basic	ADJ
fnp-3528	333	3	operations	operation	NOUN
fnp-3528	333	4	were	be	AUX
fnp-3528	333	5	the	the	DET
fnp-3528	333	6	categorization	categorization	NOUN
fnp-3528	333	7	of	of	ADP
fnp-3528	333	8	bioactive	bioactive	ADJ
fnp-3528	333	9	molecules	molecule	NOUN
fnp-3528	333	10	according	accord	VERB
fnp-3528	333	11	to	to	ADP
fnp-3528	333	12	their	their	PRON
fnp-3528	333	13	inhibitory	inhibitory	ADJ
fnp-3528	333	14	power	power	NOUN
fnp-3528	333	15	against	against	ADP
fnp-3528	333	16	specific	specific	ADJ
fnp-3528	333	17	abc	abc	PROPN
fnp-3528	333	18	transporters	transporter	NOUN
fnp-3528	333	19	and	and	CCONJ
fnp-3528	333	20	their	their	PRON
fnp-3528	333	21	classification	classification	NOUN
fnp-3528	333	22	according	accord	VERB
fnp-3528	333	23	to	to	ADP
fnp-3528	333	24	their	their	PRON
fnp-3528	333	25	selectivity	selectivity	NOUN
fnp-3528	333	26	profile	profile	NOUN
fnp-3528	333	27	.	.	PUNCT
fnp-3528	334	1	the	the	DET
fnp-3528	334	2	respective	respective	ADJ
fnp-3528	334	3	classes	class	NOUN
fnp-3528	334	4	can	can	AUX
fnp-3528	334	5	statistically	statistically	ADV
fnp-3528	334	6	be	be	AUX
fnp-3528	334	7	analyzed	analyze	VERB
fnp-3528	334	8	for	for	SCONJ
fnp-3528	334	9	both	both	PRON
fnp-3528	334	10	their	their	PRON
fnp-3528	334	11	basic	basic	ADJ
fnp-3528	334	12	scaffolds	scaffold	NOUN
fnp-3528	334	13	and/or	and/or	CCONJ
fnp-3528	334	14	their	their	PRON
fnp-3528	334	15	substructural	substructural	ADJ
fnp-3528	334	16	composition	composition	NOUN
fnp-3528	334	17	to	to	PART
fnp-3528	334	18	extract	extract	VERB
fnp-3528	334	19	the	the	DET
fnp-3528	334	20	desired	desire	VERB
fnp-3528	334	21	pharmacological	pharmacological	NOUN
fnp-3528	334	22	profile	profile	NOUN
fnp-3528	334	23	and	and	CCONJ
fnp-3528	334	24	target	target	VERB
fnp-3528	334	25	preferences	preference	NOUN
fnp-3528	334	26	.	.	PUNCT
fnp-3528	335	1	the	the	DET
fnp-3528	335	2	generated	generate	VERB
fnp-3528	335	3	model	model	NOUN
fnp-3528	335	4	focused	focus	VERB
fnp-3528	335	5	multitargeting	multitargeting	NOUN
fnp-3528	335	6	of	of	ADP
fnp-3528	335	7	abc	abc	PROPN
fnp-3528	335	8	transporters	transporter	NOUN
fnp-3528	335	9	,	,	PUNCT
fnp-3528	335	10	and	and	CCONJ
fnp-3528	335	11	resulted	result	VERB
fnp-3528	335	12	in	in	ADP
fnp-3528	335	13	a	a	DET
fnp-3528	335	14	biological	biological	ADJ
fnp-3528	335	15	hit	hit	NOUN
fnp-3528	335	16	rate	rate	NOUN
fnp-3528	335	17	of	of	ADP
fnp-3528	335	18	21.7%.19	21.7%.19	NOUN
fnp-3528	335	19	adaption	adaption	NOUN
fnp-3528	335	20	of	of	ADP
fnp-3528	335	21	the	the	DET
fnp-3528	335	22	model	model	NOUN
fnp-3528	335	23	(	(	PUNCT
fnp-3528	335	24	‘	'	PUNCT
fnp-3528	335	25	c@pa_1.2	c@pa_1.2	NOUN
fnp-3528	335	26	’	'	PUNCT
fnp-3528	335	27	)	)	PUNCT
fnp-3528	335	28	through	through	ADP
fnp-3528	335	29	additional	additional	ADJ
fnp-3528	335	30	non	non	ADJ
fnp-3528	335	31	-	-	ADJ
fnp-3528	335	32	statistical	statistical	ADJ
fnp-3528	335	33	and	and	CCONJ
fnp-3528	335	34	exploratory	exploratory	ADJ
fnp-3528	335	35	measures	measure	NOUN
fnp-3528	335	36	increased	increase	VERB
fnp-3528	335	37	the	the	DET
fnp-3528	335	38	biological	biological	ADJ
fnp-3528	335	39	hit	hit	NOUN
fnp-3528	335	40	rate	rate	NOUN
fnp-3528	335	41	to	to	ADP
fnp-3528	335	42	40%,18	40%,18	NOUN
fnp-3528	335	43	and	and	CCONJ
fnp-3528	335	44	an	an	DET
fnp-3528	335	45	additional	additional	ADJ
fnp-3528	335	46	extension	extension	NOUN
fnp-3528	335	47	of	of	ADP
fnp-3528	335	48	the	the	DET
fnp-3528	335	49	model	model	NOUN
fnp-3528	335	50	enabled	enable	VERB
fnp-3528	335	51	the	the	DET
fnp-3528	335	52	discovery	discovery	NOUN
fnp-3528	335	53	of	of	ADP
fnp-3528	335	54	the	the	DET
fnp-3528	335	55	‘	'	PUNCT
fnp-3528	335	56	outer	outer	ADJ
fnp-3528	335	57	multitarget	multitarget	NOUN
fnp-3528	335	58	modulator	modulator	NOUN
fnp-3528	335	59	landscape	landscape	NOUN
fnp-3528	335	60	’	'	PUNCT
fnp-3528	335	61	,	,	PUNCT
fnp-3528	335	62	which	which	PRON
fnp-3528	335	63	represented	represent	VERB
fnp-3528	335	64	weak	weak	ADJ
fnp-3528	335	65	multitarget	multitarget	NOUN
fnp-3528	335	66	bioactivities	bioactivitie	NOUN
fnp-3528	335	67	(	(	PUNCT
fnp-3528	335	68	>	>	SYM
fnp-3528	335	69	10	10	NUM
fnp-3528	335	70	μm	μm	NOUN
fnp-3528	335	71	)	)	PUNCT
fnp-3528	335	72	supporting	support	VERB
fnp-3528	335	73	the	the	DET
fnp-3528	335	74	discovery	discovery	NOUN
fnp-3528	335	75	of	of	ADP
fnp-3528	335	76	a	a	DET
fnp-3528	335	77	larger	large	ADJ
fnp-3528	335	78	number	number	NOUN
fnp-3528	335	79	of	of	ADP
fnp-3528	335	80	multitarget	multitarget	PROPN
fnp-3528	335	81	agents.495	agents.495	ADP
fnp-3528	335	82	the	the	DET
fnp-3528	335	83	hit	hit	NOUN
fnp-3528	335	84	rates	rate	NOUN
fnp-3528	335	85	are	be	AUX
fnp-3528	335	86	impressive	impressive	ADJ
fnp-3528	335	87	considering	consider	VERB
fnp-3528	335	88	that	that	SCONJ
fnp-3528	335	89	this	this	DET
fnp-3528	335	90	approach	approach	NOUN
fnp-3528	335	91	takes	take	VERB
fnp-3528	335	92	several	several	ADJ
fnp-3528	335	93	targets	target	NOUN
fnp-3528	335	94	with	with	ADP
fnp-3528	335	95	individual	individual	ADJ
fnp-3528	335	96	‘	'	PUNCT
fnp-3528	335	97	ligand	ligand	ADJ
fnp-3528	335	98	preferences	preference	NOUN
fnp-3528	335	99	’	'	PUNCT
fnp-3528	335	100	into	into	ADP
fnp-3528	335	101	account	account	NOUN
fnp-3528	335	102	.	.	PUNCT
fnp-3528	336	1	furthermore	furthermore	ADV
fnp-3528	336	2	,	,	PUNCT
fnp-3528	336	3	as	as	SCONJ
fnp-3528	336	4	several	several	ADJ
fnp-3528	336	5	abc	abc	PROPN
fnp-3528	336	6	transporters	transporter	NOUN
fnp-3528	336	7	of	of	ADP
fnp-3528	336	8	distinct	distinct	ADJ
fnp-3528	336	9	subfamilies	subfamily	NOUN
fnp-3528	336	10	were	be	AUX
fnp-3528	336	11	considered	consider	VERB
fnp-3528	336	12	(	(	PUNCT
fnp-3528	336	13	abcb1	abcb1	NOUN
fnp-3528	336	14	,	,	PUNCT
fnp-3528	336	15	abcc1	abcc1	PROPN
fnp-3528	336	16	,	,	PUNCT
fnp-3528	336	17	abcg2	abcg2	NOUN
fnp-3528	336	18	)	)	PUNCT
fnp-3528	336	19	,	,	PUNCT
fnp-3528	336	20	the	the	DET
fnp-3528	336	21	resultant	resultant	NOUN
fnp-3528	336	22	multitarget	multitarget	PROPN
fnp-3528	336	23	agents	agent	NOUN
fnp-3528	336	24	open	open	VERB
fnp-3528	336	25	up	up	ADP
fnp-3528	336	26	the	the	DET
fnp-3528	336	27	possibility	possibility	NOUN
fnp-3528	336	28	to	to	PART
fnp-3528	336	29	explore	explore	VERB
fnp-3528	336	30	under	under	ADP
fnp-3528	336	31	-	-	PUNCT
fnp-3528	336	32	studied	study	VERB
fnp-3528	336	33	abc	abc	PROPN
fnp-3528	336	34	transporters,18	transporters,18	NOUN
fnp-3528	336	35	in	in	ADP
fnp-3528	336	36	particular	particular	ADJ
fnp-3528	336	37	abca	abca	NOUN
fnp-3528	336	38	transporters	transporter	NOUN
fnp-3528	336	39	in	in	ADP
fnp-3528	336	40	terms	term	NOUN
fnp-3528	336	41	of	of	ADP
fnp-3528	336	42	ad.6,14	ad.6,14	ADV
fnp-3528	336	43	combined	combined	ADJ
fnp-3528	336	44	approaches	approach	NOUN
fnp-3528	336	45	apart	apart	ADV
fnp-3528	336	46	from	from	ADP
fnp-3528	336	47	the	the	DET
fnp-3528	336	48	individual	individual	ADJ
fnp-3528	336	49	use	use	NOUN
fnp-3528	336	50	of	of	ADP
fnp-3528	336	51	these	these	DET
fnp-3528	336	52	methodologies	methodology	NOUN
fnp-3528	336	53	,	,	PUNCT
fnp-3528	336	54	combined	combine	VERB
fnp-3528	336	55	approaches	approach	NOUN
fnp-3528	336	56	may	may	AUX
fnp-3528	336	57	lead	lead	VERB
fnp-3528	336	58	to	to	ADP
fnp-3528	336	59	improved	improved	ADJ
fnp-3528	336	60	hit	hit	NOUN
fnp-3528	336	61	rates	rate	NOUN
fnp-3528	336	62	and	and	CCONJ
fnp-3528	336	63	better	well	ADJ
fnp-3528	336	64	prediction	prediction	NOUN
fnp-3528	336	65	capabilities	capability	NOUN
fnp-3528	336	66	with	with	ADP
fnp-3528	336	67	respect	respect	NOUN
fnp-3528	336	68	to	to	ADP
fnp-3528	336	69	bioactivity	bioactivity	NOUN
fnp-3528	336	70	of	of	ADP
fnp-3528	336	71	small	small	ADJ
fnp-3528	336	72	-	-	PUNCT
fnp-3528	336	73	molecules	molecule	NOUN
fnp-3528	336	74	.	.	PUNCT
fnp-3528	337	1	this	this	PRON
fnp-3528	337	2	has	have	AUX
fnp-3528	337	3	in	in	ADP
fnp-3528	337	4	particular	particular	ADJ
fnp-3528	337	5	been	be	AUX
fnp-3528	337	6	demonstrated	demonstrate	VERB
fnp-3528	337	7	for	for	ADP
fnp-3528	337	8	a	a	DET
fnp-3528	337	9	combined	combine	VERB
fnp-3528	337	10	virtual	virtual	ADJ
fnp-3528	337	11	screening	screening	NOUN
fnp-3528	337	12	approach	approach	NOUN
fnp-3528	337	13	using	use	VERB
fnp-3528	337	14	similarity	similarity	NOUN
fnp-3528	337	15	search	search	NOUN
fnp-3528	337	16	and	and	CCONJ
fnp-3528	337	17	pharmacophore	pharmacophore	NOUN
fnp-3528	337	18	modelling	modelling	NOUN
fnp-3528	337	19	for	for	ADP
fnp-3528	337	20	the	the	DET
fnp-3528	337	21	discovery	discovery	NOUN
fnp-3528	337	22	of	of	ADP
fnp-3528	337	23	novel	novel	ADJ
fnp-3528	337	24	abcc1	abcc1	PROPN
fnp-3528	338	1	inhibitors.493	inhibitors.493	ADV
fnp-3528	338	2	also	also	ADV
fnp-3528	338	3	,	,	PUNCT
fnp-3528	338	4	certain	certain	ADJ
fnp-3528	338	5	pattern	pattern	NOUN
fnp-3528	338	6	analysis	analysis	NOUN
fnp-3528	338	7	approaches	approach	NOUN
fnp-3528	338	8	have	have	AUX
fnp-3528	338	9	used	use	VERB
fnp-3528	338	10	a	a	DET
fnp-3528	338	11	data	data	NOUN
fnp-3528	338	12	set	set	VERB
fnp-3528	338	13	derived	derive	VERB
fnp-3528	338	14	from	from	ADP
fnp-3528	338	15	a	a	DET
fnp-3528	338	16	similarity	similarity	NOUN
fnp-3528	338	17	search	search	NOUN
fnp-3528	338	18	and	and	CCONJ
fnp-3528	338	19	pharmacophore	pharmacophore	NOUN
fnp-3528	338	20	modelling	modelling	NOUN
fnp-3528	338	21	approach	approach	NOUN
fnp-3528	338	22	,	,	PUNCT
fnp-3528	338	23	and	and	CCONJ
fnp-3528	338	24	hence	hence	ADV
fnp-3528	338	25	,	,	PUNCT
fnp-3528	338	26	can	can	AUX
fnp-3528	338	27	also	also	ADV
fnp-3528	338	28	be	be	AUX
fnp-3528	338	29	considered	consider	VERB
fnp-3528	338	30	a	a	DET
fnp-3528	338	31	combined	combined	ADJ
fnp-3528	338	32	computational	computational	ADJ
fnp-3528	338	33	approach.18,495	approach.18,495	NOUN
fnp-3528	338	34	in	in	ADP
fnp-3528	338	35	vitro	vitro	X
fnp-3528	338	36	methodologies	methodology	NOUN
fnp-3528	338	37	to	to	PART
fnp-3528	338	38	assess	assess	VERB
fnp-3528	338	39	novel	novel	ADJ
fnp-3528	338	40	lead	lead	NOUN
fnp-3528	338	41	structures	structure	NOUN
fnp-3528	338	42	the	the	DET
fnp-3528	338	43	previous	previous	ADJ
fnp-3528	338	44	sections	section	NOUN
fnp-3528	338	45	have	have	AUX
fnp-3528	338	46	already	already	ADV
fnp-3528	338	47	outlined	outline	VERB
fnp-3528	338	48	the	the	DET
fnp-3528	338	49	diverse	diverse	ADJ
fnp-3528	338	50	testing	testing	NOUN
fnp-3528	338	51	systems	system	NOUN
fnp-3528	338	52	that	that	PRON
fnp-3528	338	53	have	have	AUX
fnp-3528	338	54	been	be	AUX
fnp-3528	338	55	used	use	VERB
fnp-3528	338	56	to	to	PART
fnp-3528	338	57	assess	assess	VERB
fnp-3528	338	58	the	the	DET
fnp-3528	338	59	modulatory	modulatory	ADJ
fnp-3528	338	60	effects	effect	NOUN
fnp-3528	338	61	of	of	ADP
fnp-3528	338	62	effectors	effector	NOUN
fnp-3528	338	63	toward	toward	ADP
fnp-3528	338	64	abca	abca	PROPN
fnp-3528	338	65	transporters	transporter	NOUN
fnp-3528	338	66	.	.	PUNCT
fnp-3528	339	1	the	the	DET
fnp-3528	339	2	following	follow	VERB
fnp-3528	339	3	section	section	NOUN
fnp-3528	339	4	will	will	AUX
fnp-3528	339	5	highlight	highlight	VERB
fnp-3528	339	6	the	the	DET
fnp-3528	339	7	abca	abca	NOUN
fnp-3528	339	8	transporter	transporter	NOUN
fnp-3528	339	9	-	-	PUNCT
fnp-3528	339	10	expressing	express	VERB
fnp-3528	339	11	host	host	NOUN
fnp-3528	339	12	systems	system	NOUN
fnp-3528	339	13	and	and	CCONJ
fnp-3528	339	14	the	the	DET
fnp-3528	339	15	related	related	ADJ
fnp-3528	339	16	assays	assay	NOUN
fnp-3528	339	17	that	that	PRON
fnp-3528	339	18	can	can	AUX
fnp-3528	339	19	be	be	AUX
fnp-3528	339	20	implemented	implement	VERB
fnp-3528	339	21	into	into	ADP
fnp-3528	339	22	the	the	DET
fnp-3528	339	23	pipeline	pipeline	NOUN
fnp-3528	339	24	for	for	ADP
fnp-3528	339	25	the	the	DET
fnp-3528	339	26	assessment	assessment	NOUN
fnp-3528	339	27	of	of	ADP
fnp-3528	339	28	novel	novel	ADJ
fnp-3528	339	29	lead	lead	NOUN
fnp-3528	339	30	molecules	molecule	NOUN
fnp-3528	339	31	as	as	ADP
fnp-3528	339	32	potential	potential	ADJ
fnp-3528	339	33	abca	abca	NOUN
fnp-3528	339	34	transporter	transporter	NOUN
fnp-3528	339	35	diagnostics	diagnostic	NOUN
fnp-3528	339	36	or	or	CCONJ
fnp-3528	339	37	therapeutics	therapeutic	NOUN
fnp-3528	339	38	.	.	PUNCT
fnp-3528	340	1	host	host	NOUN
fnp-3528	340	2	system	system	NOUN
fnp-3528	340	3	of	of	ADP
fnp-3528	340	4	abca	abca	PROPN
fnp-3528	340	5	transporters	transporter	NOUN
fnp-3528	340	6	the	the	DET
fnp-3528	340	7	transporter	transporter	NOUN
fnp-3528	340	8	host	host	NOUN
fnp-3528	340	9	system	system	NOUN
fnp-3528	340	10	(	(	PUNCT
fnp-3528	340	11	abca	abca	NOUN
fnp-3528	340	12	transporter	transporter	NOUN
fnp-3528	340	13	carrying	carry	VERB
fnp-3528	340	14	unit	unit	NOUN
fnp-3528	340	15	)	)	PUNCT
fnp-3528	340	16	can	can	AUX
fnp-3528	340	17	be	be	AUX
fnp-3528	340	18	categorized	categorize	VERB
fnp-3528	340	19	into	into	ADP
fnp-3528	340	20	(	(	PUNCT
fnp-3528	340	21	i	i	NOUN
fnp-3528	340	22	)	)	PUNCT
fnp-3528	340	23	living	living	NOUN
fnp-3528	340	24	-	-	PUNCT
fnp-3528	340	25	cell	cell	NOUN
fnp-3528	340	26	-	-	PUNCT
fnp-3528	340	27	based	base	VERB
fnp-3528	340	28	or	or	CCONJ
fnp-3528	340	29	(	(	PUNCT
fnp-3528	340	30	ii	ii	NOUN
fnp-3528	340	31	)	)	PUNCT
fnp-3528	340	32	membrane	membrane	NOUN
fnp-3528	340	33	preparation-/vesicle	preparation-/vesicle	NOUN
fnp-3528	340	34	-	-	PUNCT
fnp-3528	340	35	based	base	VERB
fnp-3528	340	36	(	(	PUNCT
fnp-3528	340	37	including	include	VERB
fnp-3528	340	38	isolated	isolate	VERB
fnp-3528	340	39	and	and	CCONJ
fnp-3528	340	40	reconstituted	reconstitute	VERB
fnp-3528	340	41	proteins	protein	NOUN
fnp-3528	340	42	)	)	PUNCT
fnp-3528	340	43	.	.	PUNCT
fnp-3528	341	1	the	the	DET
fnp-3528	341	2	vast	vast	ADJ
fnp-3528	341	3	majority	majority	NOUN
fnp-3528	341	4	of	of	ADP
fnp-3528	341	5	biological	biological	ADJ
fnp-3528	341	6	investigations	investigation	NOUN
fnp-3528	341	7	used	use	VERB
fnp-3528	341	8	living	living	NOUN
fnp-3528	341	9	cells	cell	NOUN
fnp-3528	341	10	.	.	PUNCT
fnp-3528	342	1	here	here	ADV
fnp-3528	342	2	,	,	PUNCT
fnp-3528	342	3	two	two	NUM
fnp-3528	342	4	different	different	ADJ
fnp-3528	342	5	living	live	VERB
fnp-3528	342	6	cell	cell	NOUN
fnp-3528	342	7	-	-	PUNCT
fnp-3528	342	8	based	base	VERB
fnp-3528	342	9	transporter	transporter	NOUN
fnp-3528	342	10	host	host	NOUN
fnp-3528	342	11	systems	system	NOUN
fnp-3528	342	12	can	can	AUX
fnp-3528	342	13	be	be	AUX
fnp-3528	342	14	differentiated	differentiate	VERB
fnp-3528	342	15	:	:	PUNCT
fnp-3528	342	16	(	(	PUNCT
fnp-3528	342	17	i	i	NOUN
fnp-3528	342	18	)	)	PUNCT
fnp-3528	342	19	native	native	ADJ
fnp-3528	342	20	/	/	SYM
fnp-3528	342	21	induced	induced	ADJ
fnp-3528	342	22	/	/	SYM
fnp-3528	342	23	selected	select	VERB
fnp-3528	342	24	cells	cell	NOUN
fnp-3528	342	25	and	and	CCONJ
fnp-3528	342	26	(	(	PUNCT
fnp-3528	342	27	ii	ii	NOUN
fnp-3528	342	28	)	)	PUNCT
fnp-3528	342	29	transfected	transfecte	VERB
fnp-3528	342	30	cells	cell	NOUN
fnp-3528	342	31	.	.	PUNCT
fnp-3528	343	1	native	native	ADJ
fnp-3528	343	2	abca	abca	PROPN
fnp-3528	343	3	transporters	transporter	NOUN
fnp-3528	343	4	-	-	PUNCT
fnp-3528	343	5	expressing	express	VERB
fnp-3528	343	6	living	live	VERB
fnp-3528	343	7	cells	cell	NOUN
fnp-3528	343	8	native	native	ADJ
fnp-3528	343	9	/	/	SYM
fnp-3528	343	10	induced	induced	ADJ
fnp-3528	343	11	/	/	SYM
fnp-3528	343	12	selected	select	VERB
fnp-3528	343	13	cells	cell	NOUN
fnp-3528	343	14	naturally	naturally	ADV
fnp-3528	343	15	express	express	VERB
fnp-3528	343	16	the	the	DET
fnp-3528	343	17	respective	respective	ADJ
fnp-3528	343	18	abca	abca	NOUN
fnp-3528	343	19	transporter	transporter	NOUN
fnp-3528	343	20	or	or	CCONJ
fnp-3528	343	21	have	have	AUX
fnp-3528	343	22	been	be	AUX
fnp-3528	343	23	exposed	expose	VERB
fnp-3528	343	24	to	to	ADP
fnp-3528	343	25	a	a	DET
fnp-3528	343	26	‘	'	PUNCT
fnp-3528	343	27	standard	standard	ADJ
fnp-3528	343	28	’	'	PUNCT
fnp-3528	343	29	inducer	inducer	NOUN
fnp-3528	343	30	,	,	PUNCT
fnp-3528	343	31	for	for	ADP
fnp-3528	343	32	example	example	NOUN
fnp-3528	343	33	,	,	PUNCT
fnp-3528	343	34	the	the	DET
fnp-3528	343	35	abca1	abca1	NOUN
fnp-3528	343	36	inducers	inducer	VERB
fnp-3528	343	37	22-(r)-hydroxycholesterol,122,205,249,252,259,262	22-(r)-hydroxycholesterol,122,205,249,252,259,262	NUM
fnp-3528	343	38	-	-	PUNCT
fnp-3528	343	39	264,268,277,278,305	264,268,277,278,305	NUM
fnp-3528	343	40	-	-	SYM
fnp-3528	343	41	315	315	NUM
fnp-3528	343	42	to901317,205,245,250,252,259,260,262,264,271,272,279	to901317,205,245,250,252,259,260,262,264,271,272,279	PROPN
fnp-3528	343	43	,	,	PUNCT
fnp-3528	343	44	280,282,308,310,317,319,322,324,326,328	280,282,308,310,317,319,322,324,326,328	NUM
fnp-3528	343	45	-	-	SYM
fnp-3528	343	46	345	345	NUM
fnp-3528	343	47	or	or	CCONJ
fnp-3528	343	48	8	8	NUM
fnp-3528	343	49	-	-	PUNCT
fnp-3528	343	50	br	br	NOUN
fnp-3528	343	51	camp,230,249,255,266,290,292	camp,230,249,255,266,290,292	NOUN
fnp-3528	343	52	and	and	CCONJ
fnp-3528	343	53	overexpress	overexpress	NOUN
fnp-3528	343	54	the	the	DET
fnp-3528	343	55	respective	respective	ADJ
fnp-3528	343	56	transporter	transporter	NOUN
fnp-3528	343	57	in	in	ADP
fnp-3528	343	58	response	response	NOUN
fnp-3528	343	59	(	(	PUNCT
fnp-3528	343	60	e.g.	e.g.	ADV
fnp-3528	343	61	,	,	PUNCT
fnp-3528	343	62	abca1	abca1	NOUN
fnp-3528	343	63	)	)	PUNCT
fnp-3528	343	64	.	.	PUNCT
fnp-3528	344	1	most	most	ADV
fnp-3528	344	2	commonly	commonly	ADV
fnp-3528	344	3	,	,	PUNCT
fnp-3528	344	4	human	human	ADJ
fnp-3528	344	5	or	or	CCONJ
fnp-3528	344	6	murine	murine	ADJ
fnp-3528	344	7	cells	cell	NOUN
fnp-3528	344	8	have	have	AUX
fnp-3528	344	9	been	be	AUX
fnp-3528	344	10	used	use	VERB
fnp-3528	344	11	.	.	PUNCT
fnp-3528	345	1	table	table	NOUN
fnp-3528	345	2	 	 	SPACE
fnp-3528	345	3	4	4	NUM
fnp-3528	345	4	summarizes	summarize	NOUN
fnp-3528	345	5	the	the	DET
fnp-3528	345	6	cell	cell	NOUN
fnp-3528	345	7	lines	line	NOUN
fnp-3528	345	8	used	use	VERB
fnp-3528	345	9	to	to	PART
fnp-3528	345	10	assess	assess	VERB
fnp-3528	345	11	the	the	DET
fnp-3528	345	12	abca	abca	NOUN
fnp-3528	345	13	transporter	transporter	NOUN
fnp-3528	345	14	modulators	modulator	NOUN
fnp-3528	345	15	discussed	discuss	VERB
fnp-3528	345	16	in	in	ADP
fnp-3528	345	17	the	the	DET
fnp-3528	345	18	previous	previous	ADJ
fnp-3528	345	19	sections	section	NOUN
fnp-3528	345	20	.	.	PUNCT
fnp-3528	346	1	it	it	PRON
fnp-3528	346	2	must	must	AUX
fnp-3528	346	3	be	be	AUX
fnp-3528	346	4	noted	note	VERB
fnp-3528	346	5	that	that	SCONJ
fnp-3528	346	6	the	the	DET
fnp-3528	346	7	addressed	address	VERB
fnp-3528	346	8	pathways	pathway	NOUN
fnp-3528	346	9	regulate	regulate	VERB
fnp-3528	346	10	also	also	ADV
fnp-3528	346	11	the	the	DET
fnp-3528	346	12	overexpression	overexpression	NOUN
fnp-3528	346	13	of	of	ADP
fnp-3528	346	14	other	other	ADJ
fnp-3528	346	15	abc	abc	PROPN
fnp-3528	346	16	transporters	transporter	NOUN
fnp-3528	346	17	.	.	PUNCT
fnp-3528	347	1	in	in	ADP
fnp-3528	347	2	terms	term	NOUN
fnp-3528	347	3	of	of	ADP
fnp-3528	347	4	the	the	DET
fnp-3528	347	5	studies	study	NOUN
fnp-3528	347	6	of	of	ADP
fnp-3528	347	7	abca1	abca1	PROPN
fnp-3528	347	8	,	,	PUNCT
fnp-3528	347	9	the	the	DET
fnp-3528	347	10	co	co	NOUN
fnp-3528	347	11	-	-	NOUN
fnp-3528	347	12	expression	expression	NOUN
fnp-3528	347	13	(	(	PUNCT
fnp-3528	347	14	i.e.	i.e.	X
fnp-3528	347	15	,	,	PUNCT
fnp-3528	347	16	co	co	NOUN
fnp-3528	347	17	-	-	NOUN
fnp-3528	347	18	upregulation	upregulation	NOUN
fnp-3528	347	19	and	and	CCONJ
fnp-3528	347	20	co	co	NOUN
fnp-3528	347	21	-	-	NOUN
fnp-3528	347	22	downregulation	downregulation	NOUN
fnp-3528	347	23	)	)	PUNCT
fnp-3528	347	24	of	of	ADP
fnp-3528	347	25	other	other	ADJ
fnp-3528	347	26	members	member	NOUN
fnp-3528	347	27	,	,	PUNCT
fnp-3528	347	28	such	such	ADJ
fnp-3528	347	29	as	as	ADP
fnp-3528	347	30	abcg1	abcg1	ADV
fnp-3528	347	31	,	,	PUNCT
fnp-3528	347	32	has	have	AUX
fnp-3528	347	33	frequently	frequently	ADV
fnp-3528	347	34	been	be	AUX
fnp-3528	347	35	observed.160,320,335,364,366,402,410,418,421,448	observed.160,320,335,364,366,402,410,418,421,448	X
fnp-3528	347	36	table	table	NOUN
fnp-3528	347	37	4	4	NUM
fnp-3528	347	38	.	.	PUNCT
fnp-3528	348	1	non	non	ADJ
fnp-3528	348	2	-	-	ADJ
fnp-3528	348	3	exhaustive	exhaustive	ADJ
fnp-3528	348	4	list	list	NOUN
fnp-3528	348	5	of	of	ADP
fnp-3528	348	6	native	native	ADJ
fnp-3528	348	7	abca	abca	NOUN
fnp-3528	348	8	transporters	transporter	NOUN
fnp-3528	348	9	-	-	PUNCT
fnp-3528	348	10	expressing	express	VERB
fnp-3528	348	11	cell	cell	NOUN
fnp-3528	348	12	lines	line	NOUN
fnp-3528	348	13	that	that	PRON
fnp-3528	348	14	have	have	AUX
fnp-3528	348	15	been	be	AUX
fnp-3528	348	16	established	establish	VERB
fnp-3528	348	17	in	in	ADP
fnp-3528	348	18	the	the	DET
fnp-3528	348	19	assessment	assessment	NOUN
fnp-3528	348	20	of	of	ADP
fnp-3528	348	21	small	small	ADJ
fnp-3528	348	22	-	-	PUNCT
fnp-3528	348	23	molecule	molecule	NOUN
fnp-3528	348	24	modulators	modulator	NOUN
fnp-3528	348	25	of	of	ADP
fnp-3528	348	26	abca	abca	NOUN
fnp-3528	348	27	transporters	transporter	NOUN
fnp-3528	348	28	.	.	PUNCT
fnp-3528	349	1	cell	cell	NOUN
fnp-3528	349	2	type	type	NOUN
fnp-3528	349	3	cell	cell	NOUN
fnp-3528	349	4	line	line	NOUN
fnp-3528	349	5	name	name	NOUN
fnp-3528	349	6	origin	origin	NOUN
fnp-3528	349	7	references	reference	NOUN
fnp-3528	349	8	abca1	abca1	NOUN
fnp-3528	349	9	colorectal	colorectal	ADJ
fnp-3528	349	10	adenocarcinoma	adenocarcinoma	NOUN
fnp-3528	349	11	cells	cell	NOUN
fnp-3528	349	12	caco-2	caco-2	NUM
fnp-3528	349	13	human	human	ADJ
fnp-3528	349	14	262,264,308,314,342,436	262,264,308,314,342,436	NUM
fnp-3528	349	15	lung	lung	NOUN
fnp-3528	349	16	adenocarcinoma	adenocarcinoma	NOUN
fnp-3528	349	17	cells	cell	NOUN
fnp-3528	349	18	hcc827	hcc827	PROPN
fnp-3528	349	19	-	-	PUNCT
fnp-3528	349	20	gr	gr	PRON
fnp-3528	349	21	pc9	pc9	NOUN
fnp-3528	349	22	-	-	PUNCT
fnp-3528	349	23	g2	g2	PROPN
fnp-3528	349	24	human	human	ADJ
fnp-3528	349	25	337	337	NUM
fnp-3528	349	26	337	337	NUM
fnp-3528	349	27	renal	renal	ADJ
fnp-3528	349	28	adenocarcinoma	adenocarcinoma	NOUN
fnp-3528	349	29	cells	cell	NOUN
fnp-3528	349	30	786	786	NUM
fnp-3528	349	31	-	-	PUNCT
fnp-3528	349	32	o	o	NOUN
fnp-3528	349	33	a498	a498	PROPN
fnp-3528	349	34	achn	achn	VERB
fnp-3528	349	35	hk-2	hk-2	PRON
fnp-3528	349	36	sn12c	sn12c	PROPN
fnp-3528	349	37	os	os	NOUN
fnp-3528	349	38	-	-	PUNCT
fnp-3528	349	39	rc-2	rc-2	NOUN
fnp-3528	349	40	human	human	PROPN
fnp-3528	349	41	human	human	PROPN
fnp-3528	349	42	human	human	PROPN
fnp-3528	349	43	human	human	PROPN
fnp-3528	349	44	human	human	PROPN
fnp-3528	349	45	human	human	PROPN
fnp-3528	349	46	334	334	NUM
fnp-3528	349	47	330	330	NUM
fnp-3528	349	48	334,349	334,349	NUM
fnp-3528	349	49	330	330	NUM
fnp-3528	349	50	330	330	NUM
fnp-3528	349	51	330	330	NUM
fnp-3528	349	52	adipocytes	adipocyte	NOUN
fnp-3528	349	53	3t3	3t3	NUM
fnp-3528	349	54	l-1	l-1	NUM
fnp-3528	350	1	mouse	mouse	NOUN
fnp-3528	350	2	255	255	NUM
fnp-3528	350	3	adrenocortical	adrenocortical	ADJ
fnp-3528	350	4	carcinoma	carcinoma	NOUN
fnp-3528	350	5	cells	cell	NOUN
fnp-3528	350	6	h295r	h295r	VERB
fnp-3528	350	7	muc-1	muc-1	VERB
fnp-3528	350	8	human	human	ADJ
fnp-3528	350	9	human	human	ADJ
fnp-3528	350	10	333,441	333,441	NUM
fnp-3528	350	11	333	333	NUM
fnp-3528	350	12	astrocytes	astrocyte	NOUN
fnp-3528	350	13	human	human	ADJ
fnp-3528	350	14	mouse	mouse	NOUN
fnp-3528	350	15	rat	rat	NOUN
fnp-3528	350	16	279	279	NUM
fnp-3528	350	17	229,279	229,279	NUM
fnp-3528	350	18	281	281	NUM
fnp-3528	350	19	astrocytoma	astrocytoma	NOUN
fnp-3528	350	20	ccfsttg1	ccfsttg1	PROPN
fnp-3528	350	21	human	human	ADJ
fnp-3528	350	22	423	423	NUM
fnp-3528	350	23	peripheral	peripheral	ADJ
fnp-3528	350	24	blood	blood	NOUN
fnp-3528	350	25	mononuclear	mononuclear	ADJ
fnp-3528	350	26	cells	cell	NOUN
fnp-3528	350	27	pbmc	pbmc	VERB
fnp-3528	350	28	human	human	ADJ
fnp-3528	350	29	411	411	NUM
fnp-3528	350	30	breast	breast	NOUN
fnp-3528	350	31	cancer	cancer	NOUN
fnp-3528	350	32	cells	cell	NOUN
fnp-3528	350	33	mcf-7	mcf-7	PART
fnp-3528	350	34	human	human	ADJ
fnp-3528	350	35	331	331	NUM
fnp-3528	350	36	pancreatic	pancreatic	ADJ
fnp-3528	350	37	β	β	NOUN
fnp-3528	350	38	-	-	NOUN
fnp-3528	350	39	cells	cell	NOUN
fnp-3528	350	40	ins-1	ins-1	PART
fnp-3528	350	41	mouse	mouse	NOUN
fnp-3528	350	42	409	409	NUM
fnp-3528	350	43	cardiomyocytes	cardiomyocyte	NOUN
fnp-3528	351	1	h9c2	h9c2	NOUN
fnp-3528	351	2	hl-1	hl-1	CCONJ
fnp-3528	351	3	rat	rat	PROPN
fnp-3528	351	4	mouse	mouse	PROPN
fnp-3528	351	5	253	253	NUM
fnp-3528	351	6	250	250	NUM
fnp-3528	351	7	aortic	aortic	ADJ
fnp-3528	351	8	endothelial	endothelial	NOUN
fnp-3528	351	9	cells	cell	NOUN
fnp-3528	351	10	haec	haec	PROPN
fnp-3528	351	11	human	human	PROPN
fnp-3528	351	12	263,269	263,269	NUM
fnp-3528	351	13	endometrial	endometrial	ADJ
fnp-3528	351	14	endothelial	endothelial	ADJ
fnp-3528	351	15	cells	cell	NOUN
fnp-3528	351	16	mouse	mouse	NOUN
fnp-3528	351	17	mouse	mouse	PROPN
fnp-3528	351	18	umbilical	umbilical	ADJ
fnp-3528	351	19	vein	vein	ADJ
fnp-3528	351	20	endothelial	endothelial	NOUN
fnp-3528	351	21	cells	cell	NOUN
fnp-3528	351	22	huvec	huvec	VERB
fnp-3528	351	23	human	human	PROPN
fnp-3528	351	24	269,364,442,496	269,364,442,496	NUM
fnp-3528	351	25	epithelial	epithelial	ADJ
fnp-3528	351	26	cells	cell	NOUN
fnp-3528	351	27	beas	beas	ADJ
fnp-3528	351	28	-	-	PUNCT
fnp-3528	351	29	b2	b2	NOUN
fnp-3528	351	30	human	human	ADJ
fnp-3528	351	31	322	322	NUM
fnp-3528	351	32	lung	lung	NOUN
fnp-3528	351	33	epithelial	epithelial	ADJ
fnp-3528	351	34	cells	cell	NOUN
fnp-3528	351	35	mouse	mouse	VERB
fnp-3528	351	36	311	311	NUM
fnp-3528	351	37	pigment	pigment	ADJ
fnp-3528	351	38	epithelial	epithelial	ADJ
fnp-3528	351	39	cells	cell	NOUN
fnp-3528	351	40	human	human	ADJ
fnp-3528	351	41	257	257	NUM
fnp-3528	351	42	mouse	mouse	NOUN
fnp-3528	351	43	mammalian	mammalian	ADJ
fnp-3528	351	44	epithelial	epithelial	ADJ
fnp-3528	351	45	cells	cell	NOUN
fnp-3528	351	46	mmec	mmec	NOUN
fnp-3528	351	47	mouse	mouse	PROPN
fnp-3528	351	48	350	350	NUM
fnp-3528	351	49	aortic	aortic	ADJ
fnp-3528	351	50	smooth	smooth	ADJ
fnp-3528	351	51	muscle	muscle	NOUN
fnp-3528	351	52	cells	cell	NOUN
fnp-3528	351	53	smc	smc	PROPN
fnp-3528	351	54	human	human	PROPN
fnp-3528	351	55	269	269	NUM
fnp-3528	351	56	vascular	vascular	ADJ
fnp-3528	351	57	smooth	smooth	ADJ
fnp-3528	351	58	muscle	muscle	NOUN
fnp-3528	351	59	cells	cell	NOUN
fnp-3528	351	60	vsmc	vsmc	VERB
fnp-3528	351	61	unspecified	unspecified	ADJ
fnp-3528	351	62	origin	origin	NOUN
fnp-3528	351	63	332	332	NUM
fnp-3528	351	64	fibroblasts	fibroblast	NOUN
fnp-3528	351	65	primary	primary	ADJ
fnp-3528	351	66	hip	hip	NOUN
fnp-3528	351	67	skin	skin	NOUN
fnp-3528	351	68	wi-38	wi-38	NOUN
fnp-3528	351	69	(	(	PUNCT
fnp-3528	351	70	embryonic	embryonic	ADJ
fnp-3528	351	71	)	)	PUNCT
fnp-3528	351	72	wi38va13	wi38va13	PROPN
fnp-3528	351	73	(	(	PUNCT
fnp-3528	351	74	embryonic	embryonic	ADJ
fnp-3528	351	75	)	)	PUNCT
fnp-3528	351	76	balb/3t3	balb/3t3	NOUN
fnp-3528	351	77	swiss	swiss	ADJ
fnp-3528	351	78	3t3	3t3	NUM
fnp-3528	351	79	human	human	PROPN
fnp-3528	351	80	human	human	PROPN
fnp-3528	351	81	human	human	PROPN
fnp-3528	351	82	mouse	mouse	PROPN
fnp-3528	351	83	mouse	mouse	PROPN
fnp-3528	351	84	230,260	230,260	NUM
fnp-3528	351	85	205,246	205,246	NUM
fnp-3528	351	86	277	277	NUM
fnp-3528	351	87	275	275	NUM
fnp-3528	351	88	312	312	NUM
fnp-3528	351	89	granulosa	granulosa	NOUN
fnp-3528	351	90	cells	cell	NOUN
fnp-3528	351	91	rat	rat	VERB
fnp-3528	351	92	443	443	NUM
fnp-3528	351	93	hair	hair	NOUN
fnp-3528	351	94	follicles	follicle	VERB
fnp-3528	351	95	human	human	ADJ
fnp-3528	351	96	282	282	NUM
fnp-3528	351	97	hepatoma	hepatoma	NOUN
fnp-3528	351	98	fu5ah	fu5ah	NOUN
fnp-3528	351	99	hep3b	hep3b	NOUN
fnp-3528	351	100	hepg2	hepg2	NOUN
fnp-3528	352	1	mcarh7777	mcarh7777	NOUN
fnp-3528	352	2	rat	rat	NOUN
fnp-3528	352	3	rat	rat	NOUN
fnp-3528	352	4	human	human	ADJ
fnp-3528	352	5	rat	rat	NOUN
fnp-3528	352	6	rat	rat	NOUN
fnp-3528	352	7	318	318	NUM
fnp-3528	352	8	231	231	NUM
fnp-3528	352	9	309,342,348,379	309,342,348,379	NUM
fnp-3528	352	10	280,312,317,367,381	280,312,317,367,381	NUM
fnp-3528	352	11	343	343	NUM
fnp-3528	352	12	insulinoma	insulinoma	NOUN
fnp-3528	352	13	cells	cell	NOUN
fnp-3528	352	14	ins-1	ins-1	PART
fnp-3528	352	15	rat	rat	NOUN
fnp-3528	352	16	405	405	NUM
fnp-3528	352	17	keratinocytes	keratinocyte	NOUN
fnp-3528	352	18	human	human	ADJ
fnp-3528	352	19	282	282	NUM
fnp-3528	352	20	embryonic	embryonic	ADJ
fnp-3528	352	21	kidney	kidney	NOUN
fnp-3528	352	22	cells	cell	NOUN
fnp-3528	352	23	human	human	ADJ
fnp-3528	352	24	312	312	NUM
fnp-3528	352	25	non	non	ADJ
fnp-3528	352	26	-	-	ADJ
fnp-3528	352	27	small	small	ADJ
fnp-3528	352	28	cell	cell	NOUN
fnp-3528	352	29	lung	lung	NOUN
fnp-3528	352	30	cancer	cancer	NOUN
fnp-3528	352	31	cells	cell	NOUN
fnp-3528	352	32	a549	a549	PROPN
fnp-3528	352	33	h1650	h1650	PROPN
fnp-3528	352	34	h1975	h1975	NOUN
fnp-3528	352	35	h358	h358	PROPN
fnp-3528	352	36	pc-9	pc-9	NOUN
fnp-3528	352	37	/	/	SYM
fnp-3528	352	38	gr	gr	PROPN
fnp-3528	352	39	human	human	PROPN
fnp-3528	352	40	human	human	PROPN
fnp-3528	352	41	human	human	PROPN
fnp-3528	352	42	human	human	PROPN
fnp-3528	352	43	human	human	PROPN
fnp-3528	352	44	322,447	322,447	NUM
fnp-3528	352	45	400	400	NUM
fnp-3528	352	46	400	400	NUM
fnp-3528	352	47	447	447	NUM
fnp-3528	352	48	400	400	NUM
fnp-3528	352	49	liver	liver	NOUN
fnp-3528	352	50	cells	cell	NOUN
fnp-3528	352	51	l02	l02	VERB
fnp-3528	352	52	human	human	ADJ
fnp-3528	352	53	406	406	NUM
fnp-3528	352	54	mantle	mantle	NOUN
fnp-3528	352	55	cell	cell	NOUN
fnp-3528	352	56	lymphoma	lymphoma	NOUN
fnp-3528	352	57	mcl	mcl	PROPN
fnp-3528	352	58	human	human	NOUN
fnp-3528	352	59	468	468	NUM
fnp-3528	352	60	macrophages	macrophage	NOUN
fnp-3528	352	61	primary	primary	ADJ
fnp-3528	352	62	human	human	PROPN
fnp-3528	352	63	268,305,339,396,398	268,305,339,396,398	NUM
fnp-3528	352	64	mouse	mouse	PROPN
fnp-3528	352	65	306,312,313,320,329,341,360,366,439,448	306,312,313,320,329,341,360,366,439,448	NUM
fnp-3528	352	66	hd11	hd11	PROPN
fnp-3528	352	67	chicken	chicken	NOUN
fnp-3528	352	68	356	356	NUM
fnp-3528	352	69	j774.a1	j774.a1	PROPN
fnp-3528	352	70	mouse	mouse	PROPN
fnp-3528	352	71	252,254,255,259,265,271,278,289	252,254,255,259,265,271,278,289	PROPN
fnp-3528	352	72	-	-	PUNCT
fnp-3528	352	73	292,384,392,393	292,384,392,393	NUM
fnp-3528	353	1	raw264.7	raw264.7	PROPN
fnp-3528	354	1	mouse	mouse	PROPN
fnp-3528	354	2	249,312,313,321,336,339,342,352,360,365,367,369,375	249,312,313,321,336,339,342,352,360,365,367,369,375	NOUN
fnp-3528	354	3	,	,	PUNCT
fnp-3528	354	4	376,381,385,399,402,404,406,408,410,416	376,381,385,399,402,404,406,408,410,416	NUM
fnp-3528	354	5	-	-	SYM
fnp-3528	354	6	419,421,424	419,421,424	NUM
fnp-3528	354	7	,	,	PUNCT
fnp-3528	354	8	425,438,442,448,497	425,438,442,448,497	NUM
fnp-3528	354	9	thp-1	thp-1	ADP
fnp-3528	354	10	human	human	NOUN
fnp-3528	354	11	231,245,249,256,268,272,275,292,308,310,312	231,245,249,256,268,272,275,292,308,310,312	PROPN
fnp-3528	354	12	-	-	PUNCT
fnp-3528	354	13	316,321	316,321	NUM
fnp-3528	354	14	,	,	PUNCT
fnp-3528	354	15	328,335,338,339,341,342,360,363,364,366,377,384	328,335,338,339,341,342,360,363,364,366,377,384	NUM
fnp-3528	354	16	,	,	PUNCT
fnp-3528	354	17	388	388	NUM
fnp-3528	354	18	-	-	SYM
fnp-3528	354	19	397	397	NUM
fnp-3528	354	20	u937	u937	PROPN
fnp-3528	354	21	human	human	ADJ
fnp-3528	354	22	307	307	NUM
fnp-3528	354	23	microglia	microglia	ADJ
fnp-3528	354	24	primary	primary	ADJ
fnp-3528	354	25	bv2	bv2	NOUN
fnp-3528	354	26	retinal	retinal	ADJ
fnp-3528	354	27	(	(	PUNCT
fnp-3528	354	28	müller	müller	PROPN
fnp-3528	354	29	cells	cells	PROPN
fnp-3528	354	30	)	)	PUNCT
fnp-3528	354	31	rat	rat	PROPN
fnp-3528	354	32	mouse	mouse	NOUN
fnp-3528	354	33	mouse	mouse	NOUN
fnp-3528	354	34	355	355	NUM
fnp-3528	354	35	126,353,380	126,353,380	NUM
fnp-3528	354	36	323	323	NUM
fnp-3528	354	37	multiple	multiple	ADJ
fnp-3528	354	38	myeloma	myeloma	NOUN
fnp-3528	354	39	mm	mm	PROPN
fnp-3528	354	40	human	human	ADJ
fnp-3528	354	41	468	468	NUM
fnp-3528	354	42	neuroblastoma	neuroblastoma	ADJ
fnp-3528	354	43	neuro-2a	neuro-2a	NOUN
fnp-3528	354	44	murine	murine	ADJ
fnp-3528	354	45	359	359	NUM
fnp-3528	354	46	neutrophils	neutrophil	NOUN
fnp-3528	354	47	primary	primary	ADJ
fnp-3528	354	48	human	human	ADJ
fnp-3528	354	49	339	339	NUM
fnp-3528	354	50	nephron	nephron	NOUN
fnp-3528	354	51	cells	cell	NOUN
fnp-3528	354	52	a6	a6	NOUN
fnp-3528	354	53	frog	frog	VERB
fnp-3528	354	54	258	258	NUM
fnp-3528	354	55	periodontal	periodontal	ADJ
fnp-3528	354	56	ligament	ligament	NOUN
fnp-3528	354	57	stem	stem	NOUN
fnp-3528	354	58	cells	cell	NOUN
fnp-3528	354	59	human	human	ADJ
fnp-3528	354	60	325	325	NUM
fnp-3528	354	61	pheochromocytoma	pheochromocytoma	NOUN
fnp-3528	354	62	pc12	pc12	PROPN
fnp-3528	354	63	rat	rat	NOUN
fnp-3528	354	64	280	280	NUM
fnp-3528	354	65	podocytes	podocyte	NOUN
fnp-3528	354	66	human	human	ADJ
fnp-3528	354	67	440	440	NUM
fnp-3528	354	68	retina	retina	NOUN
fnp-3528	354	69	cells	cell	NOUN
fnp-3528	354	70	arpe-19	arpe-19	PROPN
fnp-3528	354	71	human	human	ADJ
fnp-3528	354	72	354	354	NUM
fnp-3528	354	73	oral	oral	ADJ
fnp-3528	354	74	squamous	squamous	ADJ
fnp-3528	354	75	cell	cell	NOUN
fnp-3528	354	76	carcinoma	carcinoma	NOUN
fnp-3528	354	77	cells	cell	NOUN
fnp-3528	354	78	cal27	cal27	VERB
fnp-3528	354	79	human	human	ADJ
fnp-3528	354	80	371	371	NUM
fnp-3528	354	81	trophoblasts	trophoblast	NOUN
fnp-3528	354	82	bewo	bewo	PROPN
fnp-3528	354	83	human	human	ADJ
fnp-3528	354	84	437	437	NUM
fnp-3528	354	85	abca2	abca2	NOUN
fnp-3528	354	86	hepatoma	hepatoma	NOUN
fnp-3528	354	87	hepg2	hepg2	VERB
fnp-3528	355	1	rat	rat	NOUN
fnp-3528	355	2	179	179	NUM
fnp-3528	355	3	ovary	ovary	ADJ
fnp-3528	355	4	carcinoma	carcinoma	NOUN
fnp-3528	355	5	skem	skem	ADJ
fnp-3528	355	6	human	human	ADJ
fnp-3528	355	7	238	238	NUM
fnp-3528	355	8	abca3	abca3	NOUN
fnp-3528	355	9	cholangiocarcinoma	cholangiocarcinoma	PROPN
fnp-3528	355	10	m214	m214	PROPN
fnp-3528	355	11	-	-	PUNCT
fnp-3528	355	12	5fur	5fur	NUM
fnp-3528	355	13	human	human	ADJ
fnp-3528	355	14	427	427	NUM
fnp-3528	355	15	lung	lung	NOUN
fnp-3528	355	16	epithelial	epithelial	ADJ
fnp-3528	355	17	cells	cell	NOUN
fnp-3528	355	18	mle-12	mle-12	NOUN
fnp-3528	355	19	mouse	mouse	VERB
fnp-3528	355	20	452	452	NUM
fnp-3528	355	21	hepatoma	hepatoma	NOUN
fnp-3528	355	22	hepg2	hepg2	VERB
fnp-3528	356	1	rat	rat	NOUN
fnp-3528	356	2	451	451	NUM
fnp-3528	356	3	leukemia	leukemia	NOUN
fnp-3528	356	4	primary	primary	NOUN
fnp-3528	356	5	(	(	PUNCT
fnp-3528	356	6	acute	acute	ADJ
fnp-3528	356	7	myeloid	myeloid	NOUN
fnp-3528	356	8	)	)	PUNCT
fnp-3528	356	9	bv173	bv173	PROPN
fnp-3528	356	10	k562	k562	PROPN
fnp-3528	356	11	lama83	lama83	VERB
fnp-3528	356	12	human	human	PROPN
fnp-3528	356	13	human	human	PROPN
fnp-3528	356	14	human	human	PROPN
fnp-3528	356	15	human	human	ADJ
fnp-3528	356	16	234	234	NUM
fnp-3528	356	17	234,236	234,236	NUM
fnp-3528	356	18	234	234	NUM
fnp-3528	356	19	235	235	NUM
fnp-3528	356	20	lung	lung	NOUN
fnp-3528	356	21	cancer	cancer	NOUN
fnp-3528	356	22	a549	a549	PROPN
fnp-3528	356	23	nci	nci	PROPN
fnp-3528	356	24	-	-	PUNCT
fnp-3528	356	25	h1650	h1650	PROPN
fnp-3528	356	26	nci	nci	PROPN
fnp-3528	356	27	-	-	PUNCT
fnp-3528	356	28	h1975	h1975	PROPN
fnp-3528	356	29	human	human	PROPN
fnp-3528	356	30	human	human	PROPN
fnp-3528	356	31	human	human	PROPN
fnp-3528	356	32	241	241	NUM
fnp-3528	356	33	241	241	NUM
fnp-3528	356	34	241	241	NUM
fnp-3528	356	35	abca5	abca5	X
fnp-3528	356	36	brain	brain	NOUN
fnp-3528	356	37	microvascular	microvascular	NOUN
fnp-3528	356	38	endothelial	endothelial	ADJ
fnp-3528	356	39	cells	cell	NOUN
fnp-3528	356	40	hbmec	hbmec	VERB
fnp-3528	356	41	human	human	ADJ
fnp-3528	356	42	428	428	NUM
fnp-3528	356	43	macrophages	macrophage	NOUN
fnp-3528	356	44	raw264.7	raw264.7	PROPN
fnp-3528	356	45	thp	thp	PROPN
fnp-3528	356	46	mouse	mouse	PROPN
fnp-3528	356	47	human	human	ADJ
fnp-3528	356	48	321	321	NUM
fnp-3528	356	49	321	321	NUM
fnp-3528	356	50	abca7	abca7	NOUN
fnp-3528	356	51	fibroblasts	fibroblast	NOUN
fnp-3528	356	52	balb/3t3	balb/3t3	PROPN
fnp-3528	356	53	wi-38	wi-38	NOUN
fnp-3528	356	54	mouse	mouse	PROPN
fnp-3528	356	55	human	human	ADJ
fnp-3528	356	56	205	205	NUM
fnp-3528	356	57	205	205	NUM
fnp-3528	356	58	macrophages	macrophage	NOUN
fnp-3528	356	59	j774.a1	j774.a1	PROPN
fnp-3528	356	60	mouse	mouse	VERB
fnp-3528	356	61	431	431	NUM
fnp-3528	356	62	in	in	ADP
fnp-3528	356	63	terms	term	NOUN
fnp-3528	356	64	of	of	ADP
fnp-3528	356	65	abca1	abca1	NOUN
fnp-3528	356	66	,	,	PUNCT
fnp-3528	356	67	most	most	ADJ
fnp-3528	356	68	studies	study	NOUN
fnp-3528	356	69	have	have	AUX
fnp-3528	356	70	been	be	AUX
fnp-3528	356	71	conducted	conduct	VERB
fnp-3528	356	72	with	with	ADP
fnp-3528	356	73	human	human	ADJ
fnp-3528	356	74	thp1,231,245,249,256,268,272,275,292,308,310,312	thp1,231,245,249,256,268,272,275,292,308,310,312	PROPN
fnp-3528	356	75	-	-	PUNCT
fnp-3528	356	76	316,321,328,335,338,339,341,342,360,363,364,366,377,384,388	316,321,328,335,338,339,341,342,360,363,364,366,377,384,388	NUM
fnp-3528	356	77	-	-	PUNCT
fnp-3528	356	78	397	397	NUM
fnp-3528	356	79	murine	murine	ADJ
fnp-3528	356	80	j774.a1,252,254,255,259,265,271,278,289	j774.a1,252,254,255,259,265,271,278,289	X
fnp-3528	356	81	-	-	PUNCT
fnp-3528	356	82	292,384,392,393	292,384,392,393	NUM
fnp-3528	356	83	or	or	CCONJ
fnp-3528	356	84	murine	murine	ADJ
fnp-3528	356	85	raw264.7	raw264.7	ADJ
fnp-3528	356	86	macrophages	macrophage	NOUN
fnp-3528	356	87	.	.	PUNCT
fnp-3528	357	1	230,249,312,313,321,336,339	230,249,312,313,321,336,339	X
fnp-3528	357	2	,	,	PUNCT
fnp-3528	357	3	342,352,360,365,367,369,375,376,381,385,399,402,404,406,408,410,416	342,352,360,365,367,369,375,376,381,385,399,402,404,406,408,410,416	PROPN
fnp-3528	357	4	-	-	PUNCT
fnp-3528	357	5	419,421,424,425,438,442,448	419,421,424,425,438,442,448	NUM
fnp-3528	357	6	in	in	ADP
fnp-3528	357	7	the	the	DET
fnp-3528	357	8	set	set	NOUN
fnp-3528	357	9	-	-	PUNCT
fnp-3528	357	10	up	up	NOUN
fnp-3528	357	11	of	of	ADP
fnp-3528	357	12	a	a	DET
fnp-3528	357	13	drug	drug	NOUN
fnp-3528	357	14	development	development	NOUN
fnp-3528	357	15	pipeline	pipeline	NOUN
fnp-3528	357	16	,	,	PUNCT
fnp-3528	357	17	these	these	DET
fnp-3528	357	18	cell	cell	NOUN
fnp-3528	357	19	lines	line	NOUN
fnp-3528	357	20	are	be	AUX
fnp-3528	357	21	the	the	DET
fnp-3528	357	22	backbone	backbone	NOUN
fnp-3528	357	23	of	of	ADP
fnp-3528	357	24	the	the	DET
fnp-3528	357	25	in	in	ADP
fnp-3528	357	26	vitro	vitro	X
fnp-3528	357	27	assessment	assessment	NOUN
fnp-3528	357	28	of	of	ADP
fnp-3528	357	29	potential	potential	ADJ
fnp-3528	357	30	candidates	candidate	NOUN
fnp-3528	357	31	.	.	PUNCT
fnp-3528	358	1	regarding	regard	VERB
fnp-3528	358	2	other	other	ADJ
fnp-3528	358	3	abca	abca	NOUN
fnp-3528	358	4	transporters	transporter	NOUN
fnp-3528	358	5	,	,	PUNCT
fnp-3528	358	6	the	the	DET
fnp-3528	358	7	situation	situation	NOUN
fnp-3528	358	8	is	be	AUX
fnp-3528	358	9	much	much	ADV
fnp-3528	358	10	more	more	ADV
fnp-3528	358	11	complicated	complicated	ADJ
fnp-3528	358	12	due	due	ADP
fnp-3528	358	13	to	to	ADP
fnp-3528	358	14	the	the	DET
fnp-3528	358	15	lack	lack	NOUN
fnp-3528	358	16	of	of	ADP
fnp-3528	358	17	cell	cell	NOUN
fnp-3528	358	18	lines	line	NOUN
fnp-3528	358	19	that	that	PRON
fnp-3528	358	20	naturally	naturally	ADV
fnp-3528	358	21	(	(	PUNCT
fnp-3528	358	22	and	and	CCONJ
fnp-3528	358	23	almost	almost	ADV
fnp-3528	358	24	exclusively	exclusively	ADV
fnp-3528	358	25	)	)	PUNCT
fnp-3528	358	26	express	express	VERB
fnp-3528	358	27	the	the	DET
fnp-3528	358	28	respective	respective	ADJ
fnp-3528	358	29	abca	abca	NOUN
fnp-3528	358	30	transporter	transporter	NOUN
fnp-3528	358	31	.	.	PUNCT
fnp-3528	359	1	consequently	consequently	ADV
fnp-3528	359	2	,	,	PUNCT
fnp-3528	359	3	these	these	DET
fnp-3528	359	4	abca	abca	NOUN
fnp-3528	359	5	transporters	transporter	NOUN
fnp-3528	359	6	are	be	AUX
fnp-3528	359	7	much	much	ADV
fnp-3528	359	8	less	less	ADV
fnp-3528	359	9	studied	study	VERB
fnp-3528	359	10	and	and	CCONJ
fnp-3528	359	11	well	well	ADV
fnp-3528	359	12	-	-	PUNCT
fnp-3528	359	13	established	establish	VERB
fnp-3528	359	14	.	.	PUNCT
fnp-3528	360	1	however	however	ADV
fnp-3528	360	2	,	,	PUNCT
fnp-3528	360	3	transfected	transfecte	VERB
fnp-3528	360	4	cell	cell	NOUN
fnp-3528	360	5	lines	line	NOUN
fnp-3528	360	6	are	be	AUX
fnp-3528	360	7	of	of	ADP
fnp-3528	360	8	great	great	ADJ
fnp-3528	360	9	help	help	NOUN
fnp-3528	360	10	to	to	PART
fnp-3528	360	11	study	study	VERB
fnp-3528	360	12	one	one	NUM
fnp-3528	360	13	particular	particular	ADJ
fnp-3528	360	14	transporter	transporter	NOUN
fnp-3528	360	15	instead	instead	ADV
fnp-3528	360	16	of	of	ADP
fnp-3528	360	17	using	use	VERB
fnp-3528	360	18	native	native	ADJ
fnp-3528	360	19	cell	cell	NOUN
fnp-3528	360	20	lines	line	NOUN
fnp-3528	360	21	that	that	PRON
fnp-3528	360	22	may	may	AUX
fnp-3528	360	23	co	co	VERB
fnp-3528	360	24	-	-	VERB
fnp-3528	360	25	express	express	VERB
fnp-3528	360	26	several	several	ADJ
fnp-3528	360	27	members	member	NOUN
fnp-3528	360	28	.	.	PUNCT
fnp-3528	361	1	abca	abca	PROPN
fnp-3528	361	2	transporters	transporter	NOUN
fnp-3528	361	3	-	-	PUNCT
fnp-3528	361	4	transfected	transfecte	VERB
fnp-3528	361	5	living	living	NOUN
fnp-3528	361	6	cells	cell	NOUN
fnp-3528	361	7	in	in	ADP
fnp-3528	361	8	terms	term	NOUN
fnp-3528	361	9	of	of	ADP
fnp-3528	361	10	abca1	abca1	NOUN
fnp-3528	361	11	,	,	PUNCT
fnp-3528	361	12	cell	cell	NOUN
fnp-3528	361	13	lines	line	NOUN
fnp-3528	361	14	transfected	transfecte	VERB
fnp-3528	361	15	with	with	ADP
fnp-3528	361	16	human	human	ADJ
fnp-3528	361	17	abca1	abca1	NOUN
fnp-3528	361	18	have	have	AUX
fnp-3528	361	19	often	often	ADV
fnp-3528	361	20	been	be	AUX
fnp-3528	361	21	used	use	VERB
fnp-3528	361	22	,	,	PUNCT
fnp-3528	361	23	e.g.	e.g.	ADV
fnp-3528	361	24	,	,	PUNCT
fnp-3528	361	25	human	human	ADJ
fnp-3528	361	26	embryonic	embryonic	ADJ
fnp-3528	361	27	kidney	kidney	NOUN
fnp-3528	361	28	(	(	PUNCT
fnp-3528	361	29	hek	hek	PROPN
fnp-3528	361	30	)	)	PUNCT
fnp-3528	361	31	cells	cell	NOUN
fnp-3528	361	32	(	(	PUNCT
fnp-3528	361	33	hek293	hek293	PROPN
fnp-3528	361	34	/	/	SYM
fnp-3528	361	35	abca1)171,201,202,249,260,267,270,275,329,352,386,464,467,498,499	abca1)171,201,202,249,260,267,270,275,329,352,386,464,467,498,499	PROPN
fnp-3528	361	36	and	and	CCONJ
fnp-3528	361	37	baby	baby	NOUN
fnp-3528	361	38	hamster	hamster	PROPN
fnp-3528	361	39	kidney	kidney	PROPN
fnp-3528	361	40	(	(	PUNCT
fnp-3528	361	41	bhk	bhk	PROPN
fnp-3528	361	42	)	)	PUNCT
fnp-3528	361	43	cells	cell	NOUN
fnp-3528	361	44	(	(	PUNCT
fnp-3528	361	45	bhk-21	bhk-21	PROPN
fnp-3528	361	46	/	/	SYM
fnp-3528	361	47	abca1).230,245,273,292,422	abca1).230,245,273,292,422	NOUN
fnp-3528	361	48	these	these	DET
fnp-3528	361	49	transporter	transporter	NOUN
fnp-3528	361	50	host	host	NOUN
fnp-3528	361	51	systems	system	NOUN
fnp-3528	361	52	have	have	AUX
fnp-3528	361	53	also	also	ADV
fnp-3528	361	54	been	be	AUX
fnp-3528	361	55	used	use	VERB
fnp-3528	361	56	to	to	PART
fnp-3528	361	57	study	study	VERB
fnp-3528	361	58	other	other	ADJ
fnp-3528	361	59	transporters	transporter	NOUN
fnp-3528	361	60	,	,	PUNCT
fnp-3528	361	61	abca2,498,500	abca2,498,500	NOUN
fnp-3528	361	62	abca3,235,241,498	abca3,235,241,498	PROPN
fnp-3528	361	63	abca4,133	abca4,133	PROPN
fnp-3528	361	64	-	-	PUNCT
fnp-3528	361	65	136,201,457,458,501,502	136,201,457,458,501,502	NUM
fnp-3528	361	66	abca5,503	abca5,503	ADJ
fnp-3528	361	67	abca7,201,202,386,422,498	abca7,201,202,386,422,498	PROPN
fnp-3528	361	68	abca8,10	abca8,10	PROPN
fnp-3528	361	69	abca12,498	abca12,498	PROPN
fnp-3528	361	70	and	and	CCONJ
fnp-3528	361	71	abca13.48	abca13.48	PROPN
fnp-3528	361	72	transfected	transfecte	VERB
fnp-3528	361	73	cells	cell	NOUN
fnp-3528	361	74	often	often	ADV
fnp-3528	361	75	express	express	VERB
fnp-3528	361	76	lower	low	ADJ
fnp-3528	361	77	levels	level	NOUN
fnp-3528	361	78	of	of	ADP
fnp-3528	361	79	the	the	DET
fnp-3528	361	80	introduced	introduce	VERB
fnp-3528	361	81	transporter	transporter	NOUN
fnp-3528	361	82	than	than	ADP
fnp-3528	361	83	native	native	ADJ
fnp-3528	361	84	cell	cell	NOUN
fnp-3528	361	85	lines	line	NOUN
fnp-3528	361	86	,	,	PUNCT
fnp-3528	361	87	which	which	PRON
fnp-3528	361	88	is	be	AUX
fnp-3528	361	89	a	a	DET
fnp-3528	361	90	problem	problem	NOUN
fnp-3528	361	91	if	if	SCONJ
fnp-3528	361	92	the	the	DET
fnp-3528	361	93	host	host	NOUN
fnp-3528	361	94	cell	cell	NOUN
fnp-3528	361	95	lines	line	NOUN
fnp-3528	361	96	(	(	PUNCT
fnp-3528	361	97	e.g.	e.g.	ADV
fnp-3528	361	98	,	,	PUNCT
fnp-3528	361	99	hek	hek	PROPN
fnp-3528	361	100	or	or	CCONJ
fnp-3528	361	101	bhk-21	bhk-21	NUM
fnp-3528	361	102	)	)	PUNCT
fnp-3528	361	103	naturally	naturally	ADV
fnp-3528	361	104	express	express	VERB
fnp-3528	361	105	other	other	ADJ
fnp-3528	361	106	abc	abc	PROPN
fnp-3528	361	107	transporters	transporter	NOUN
fnp-3528	361	108	as	as	ADV
fnp-3528	361	109	well	well	ADV
fnp-3528	361	110	.	.	PUNCT
fnp-3528	362	1	however	however	ADV
fnp-3528	362	2	,	,	PUNCT
fnp-3528	362	3	these	these	DET
fnp-3528	362	4	transporter	transporter	NOUN
fnp-3528	362	5	host	host	NOUN
fnp-3528	362	6	systems	system	NOUN
fnp-3528	362	7	are	be	AUX
fnp-3528	362	8	suitable	suitable	ADJ
fnp-3528	362	9	to	to	PART
fnp-3528	362	10	confirm	confirm	VERB
fnp-3528	362	11	results	result	NOUN
fnp-3528	362	12	,	,	PUNCT
fnp-3528	362	13	and	and	CCONJ
fnp-3528	362	14	might	might	AUX
fnp-3528	362	15	be	be	AUX
fnp-3528	362	16	the	the	DET
fnp-3528	362	17	only	only	ADJ
fnp-3528	362	18	possibility	possibility	NOUN
fnp-3528	362	19	to	to	PART
fnp-3528	362	20	address	address	VERB
fnp-3528	362	21	abca	abca	NOUN
fnp-3528	362	22	transporters	transporter	NOUN
fnp-3528	362	23	other	other	ADJ
fnp-3528	362	24	than	than	ADP
fnp-3528	362	25	abca1	abca1	NOUN
fnp-3528	362	26	.	.	PUNCT
fnp-3528	363	1	isolated	isolate	VERB
fnp-3528	363	2	abca	abca	NOUN
fnp-3528	363	3	transport	transport	NOUN
fnp-3528	363	4	proteins	protein	NOUN
fnp-3528	363	5	finally	finally	ADV
fnp-3528	363	6	,	,	PUNCT
fnp-3528	363	7	apart	apart	ADV
fnp-3528	363	8	from	from	ADP
fnp-3528	363	9	intact	intact	ADJ
fnp-3528	363	10	cells	cell	NOUN
fnp-3528	363	11	,	,	PUNCT
fnp-3528	363	12	vesicles	vesicle	NOUN
fnp-3528	363	13	of	of	ADP
fnp-3528	363	14	enriched	enrich	VERB
fnp-3528	363	15	or	or	CCONJ
fnp-3528	363	16	purified	purify	VERB
fnp-3528	363	17	/	/	SYM
fnp-3528	363	18	reconstituted	reconstitute	VERB
fnp-3528	363	19	abca	abca	NOUN
fnp-3528	363	20	transporters	transporter	NOUN
fnp-3528	363	21	have	have	AUX
fnp-3528	363	22	also	also	ADV
fnp-3528	363	23	been	be	AUX
fnp-3528	363	24	used	use	VERB
fnp-3528	363	25	to	to	PART
fnp-3528	363	26	assess	assess	VERB
fnp-3528	363	27	transporter	transporter	NOUN
fnp-3528	363	28	function	function	NOUN
fnp-3528	363	29	.	.	PUNCT
fnp-3528	364	1	compared	compare	VERB
fnp-3528	364	2	with	with	ADP
fnp-3528	364	3	living	live	VERB
fnp-3528	364	4	-	-	PUNCT
fnp-3528	364	5	cell	cell	NOUN
fnp-3528	364	6	based	base	VERB
fnp-3528	364	7	assays	assay	NOUN
fnp-3528	364	8	,	,	PUNCT
fnp-3528	364	9	this	this	DET
fnp-3528	364	10	kind	kind	NOUN
fnp-3528	364	11	of	of	ADP
fnp-3528	364	12	host	host	NOUN
fnp-3528	364	13	system	system	NOUN
fnp-3528	364	14	is	be	AUX
fnp-3528	364	15	rarely	rarely	ADV
fnp-3528	364	16	represented	represent	VERB
fnp-3528	364	17	in	in	ADP
fnp-3528	364	18	the	the	DET
fnp-3528	364	19	literature	literature	NOUN
fnp-3528	364	20	regarding	regard	VERB
fnp-3528	364	21	abca	abca	PROPN
fnp-3528	364	22	transporters.133	transporters.133	PROPN
fnp-3528	364	23	-	-	PUNCT
fnp-3528	364	24	139,201,499	139,201,499	NUM
fnp-3528	364	25	-	-	PUNCT
fnp-3528	364	26	502,504	502,504	NUM
fnp-3528	364	27	-	-	PUNCT
fnp-3528	364	28	506	506	NUM
fnp-3528	364	29	specifically	specifically	ADV
fnp-3528	364	30	atpase	atpase	ADJ
fnp-3528	364	31	assays	assay	NOUN
fnp-3528	364	32	are	be	AUX
fnp-3528	364	33	popular	popular	ADJ
fnp-3528	364	34	to	to	PART
fnp-3528	364	35	assess	assess	VERB
fnp-3528	364	36	functional	functional	ADJ
fnp-3528	364	37	abc	abc	PROPN
fnp-3528	364	38	transporter	transporter	PROPN
fnp-3528	364	39	modulation.23,24,507	modulation.23,24,507	NOUN
fnp-3528	364	40	-	-	ADJ
fnp-3528	364	41	510	510	NUM
fnp-3528	364	42	while	while	SCONJ
fnp-3528	364	43	transport	transport	NOUN
fnp-3528	364	44	protein	protein	NOUN
fnp-3528	364	45	purification	purification	NOUN
fnp-3528	364	46	and	and	CCONJ
fnp-3528	364	47	reconstitution	reconstitution	NOUN
fnp-3528	364	48	in	in	ADP
fnp-3528	364	49	vesicles	vesicle	NOUN
fnp-3528	364	50	or	or	CCONJ
fnp-3528	364	51	nano	nano	NOUN
fnp-3528	364	52	discs	disc	NOUN
fnp-3528	364	53	requires	require	VERB
fnp-3528	364	54	advanced	advanced	ADJ
fnp-3528	364	55	engineering	engineering	NOUN
fnp-3528	364	56	,	,	PUNCT
fnp-3528	364	57	and	and	CCONJ
fnp-3528	364	58	is	be	AUX
fnp-3528	364	59	expensive	expensive	ADJ
fnp-3528	364	60	and	and	CCONJ
fnp-3528	364	61	resource	resource	NOUN
fnp-3528	364	62	-	-	PUNCT
fnp-3528	364	63	consuming	consume	VERB
fnp-3528	364	64	,	,	PUNCT
fnp-3528	364	65	membrane	membrane	ADJ
fnp-3528	364	66	preparations	preparation	NOUN
fnp-3528	364	67	of	of	ADP
fnp-3528	364	68	transporters	transporter	NOUN
fnp-3528	364	69	,	,	PUNCT
fnp-3528	364	70	in	in	ADP
fnp-3528	364	71	particular	particular	ADJ
fnp-3528	364	72	for	for	ADP
fnp-3528	364	73	atpase	atpase	PROPN
fnp-3528	364	74	assays	assay	NOUN
fnp-3528	364	75	,	,	PUNCT
fnp-3528	364	76	are	be	AUX
fnp-3528	364	77	much	much	ADV
fnp-3528	364	78	more	more	ADV
fnp-3528	364	79	feasible	feasible	ADJ
fnp-3528	364	80	.	.	PUNCT
fnp-3528	365	1	however	however	ADV
fnp-3528	365	2	,	,	PUNCT
fnp-3528	365	3	this	this	DET
fnp-3528	365	4	method	method	NOUN
fnp-3528	365	5	has	have	AUX
fnp-3528	365	6	been	be	AUX
fnp-3528	365	7	used	use	VERB
fnp-3528	365	8	somewhat	somewhat	ADV
fnp-3528	365	9	scarcely	scarcely	ADV
fnp-3528	365	10	for	for	ADP
fnp-3528	365	11	abca	abca	NOUN
fnp-3528	365	12	transporter	transporter	NOUN
fnp-3528	365	13	function	function	NOUN
fnp-3528	365	14	assessment.133	assessment.133	NOUN
fnp-3528	365	15	-	-	NOUN
fnp-3528	365	16	135,137	135,137	NUM
fnp-3528	365	17	-	-	PUNCT
fnp-3528	365	18	139,201,499	139,201,499	NUM
fnp-3528	365	19	-	-	PUNCT
fnp-3528	365	20	502,504	502,504	NUM
fnp-3528	365	21	-	-	PUNCT
fnp-3528	365	22	506	506	NUM
fnp-3528	365	23	functional	functional	ADJ
fnp-3528	365	24	assessment	assessment	NOUN
fnp-3528	365	25	of	of	ADP
fnp-3528	365	26	abca	abca	PROPN
fnp-3528	365	27	transporters	transporter	NOUN
fnp-3528	365	28	two	two	NUM
fnp-3528	365	29	groups	group	NOUN
fnp-3528	365	30	of	of	ADP
fnp-3528	365	31	tracers	tracer	NOUN
fnp-3528	365	32	have	have	AUX
fnp-3528	365	33	been	be	AUX
fnp-3528	365	34	established	establish	VERB
fnp-3528	365	35	in	in	ADP
fnp-3528	365	36	terms	term	NOUN
fnp-3528	365	37	of	of	ADP
fnp-3528	365	38	abca	abca	NOUN
fnp-3528	365	39	transporter	transporter	NOUN
fnp-3528	365	40	function	function	NOUN
fnp-3528	365	41	:	:	PUNCT
fnp-3528	365	42	(	(	PUNCT
fnp-3528	365	43	i	i	NOUN
fnp-3528	365	44	)	)	PUNCT
fnp-3528	365	45	radiolabeled	radiolabele	VERB
fnp-3528	365	46	substrates,250,272,305,306,338,339,354,364,366,393,395,404,419,511,512,136,222,230,245,249,253,255,259,260,262,264,265,267	substrates,250,272,305,306,338,339,354,364,366,393,395,404,419,511,512,136,222,230,245,249,253,255,259,260,262,264,265,267	PROPN
fnp-3528	365	47	-	-	PUNCT
fnp-3528	365	48	270	270	NUM
fnp-3528	365	49	,	,	PUNCT
fnp-3528	365	50	273,276,278,289	273,276,278,289	NUM
fnp-3528	365	51	-	-	SYM
fnp-3528	365	52	292,311,313,315,318,329,341,367,377,381,384,385,464,467,499,513	292,311,313,315,318,329,341,367,377,381,384,385,464,467,499,513	NUM
fnp-3528	365	53	and	and	CCONJ
fnp-3528	365	54	(	(	PUNCT
fnp-3528	365	55	ii	ii	NOUN
fnp-3528	365	56	)	)	PUNCT
fnp-3528	365	57	fluorescent	fluorescent	NOUN
fnp-3528	365	58	substrates.171,201,238	substrates.171,201,238	PROPN
fnp-3528	365	59	,	,	PUNCT
fnp-3528	365	60	251,252,254,256,258,261,271,282,308,319,321,330,332,335,342,360,379,389,390,392,397,402,406,455,456,468,514	251,252,254,256,258,261,271,282,308,319,321,330,332,335,342,360,379,389,390,392,397,402,406,455,456,468,514	NUM
fnp-3528	365	61	-	-	SYM
fnp-3528	365	62	518	518	NUM
fnp-3528	365	63	  	  	SPACE
fnp-3528	365	64	radiolabeled	radiolabele	VERB
fnp-3528	365	65	tracers	tracer	NOUN
fnp-3528	365	66	of	of	ADP
fnp-3528	365	67	abca	abca	PROPN
fnp-3528	365	68	transport	transport	NOUN
fnp-3528	365	69	function	function	NOUN
fnp-3528	365	70	in	in	ADP
fnp-3528	365	71	terms	term	NOUN
fnp-3528	365	72	of	of	ADP
fnp-3528	365	73	radiolabeled	radiolabele	VERB
fnp-3528	365	74	substrates	substrate	NOUN
fnp-3528	365	75	,	,	PUNCT
fnp-3528	365	76	cholesterol	cholesterol	NOUN
fnp-3528	365	77	is	be	AUX
fnp-3528	365	78	by	by	ADP
fnp-3528	365	79	far	far	ADV
fnp-3528	365	80	the	the	DET
fnp-3528	365	81	most	most	ADV
fnp-3528	365	82	frequently	frequently	ADV
fnp-3528	365	83	used	use	VERB
fnp-3528	365	84	genuineabca1	genuineabca1	NOUN
fnp-3528	365	85	substrate,230,245,249,255,260,264,265,267	substrate,230,245,249,255,260,264,265,267	PROPN
fnp-3528	365	86	-	-	PUNCT
fnp-3528	365	87	270,272,273,276,278,289	270,272,273,276,278,289	NUM
fnp-3528	365	88	-	-	PUNCT
fnp-3528	365	89	292,305,306,313,315,318,329,338,339,354,366,367,381,384,385	292,305,306,313,315,318,329,338,339,354,366,367,381,384,385	NUM
fnp-3528	365	90	,	,	PUNCT
fnp-3528	365	91	393	393	NUM
fnp-3528	365	92	-	-	SYM
fnp-3528	365	93	395,404,408,419,464,467,499,512	395,404,408,419,464,467,499,512	PROPN
fnp-3528	365	94	followed	follow	VERB
fnp-3528	365	95	by	by	ADP
fnp-3528	365	96	phospholipid(-components).249,255,267,269,273,311,464,467,514	phospholipid(-components).249,255,267,269,273,311,464,467,514	NOUN
fnp-3528	365	97	however	however	ADV
fnp-3528	365	98	,	,	PUNCT
fnp-3528	365	99	other	other	ADJ
fnp-3528	365	100	substrates	substrate	NOUN
fnp-3528	365	101	have	have	AUX
fnp-3528	365	102	also	also	ADV
fnp-3528	365	103	been	be	AUX
fnp-3528	365	104	used	use	VERB
fnp-3528	365	105	.	.	PUNCT
fnp-3528	366	1	these	these	DET
fnp-3528	366	2	substrates	substrate	NOUN
fnp-3528	366	3	include	include	VERB
fnp-3528	366	4	mostly	mostly	ADV
fnp-3528	366	5	molecules	molecule	NOUN
fnp-3528	366	6	with	with	ADP
fnp-3528	366	7	sterane	sterane	NOUN
fnp-3528	366	8	scaffold	scaffold	NOUN
fnp-3528	366	9	,	,	PUNCT
fnp-3528	366	10	such	such	ADJ
fnp-3528	366	11	as	as	ADP
fnp-3528	366	12	β	β	NOUN
fnp-3528	366	13	-	-	NOUN
fnp-3528	366	14	sitosterol	sitosterol	NOUN
fnp-3528	366	15	(	(	PUNCT
fnp-3528	366	16	abca1)262	abca1)262	PROPN
fnp-3528	366	17	and	and	CCONJ
fnp-3528	366	18	estradiol	estradiol	PROPN
fnp-3528	366	19	-	-	PUNCT
fnp-3528	366	20	β	β	NOUN
fnp-3528	366	21	-	-	ADJ
fnp-3528	366	22	glucuronide	glucuronide	ADJ
fnp-3528	366	23	(	(	PUNCT
fnp-3528	366	24	abca8).222	abca8).222	ADV
fnp-3528	366	25	moreover	moreover	ADV
fnp-3528	366	26	,	,	PUNCT
fnp-3528	366	27	lipid	lipid	NOUN
fnp-3528	366	28	-	-	PUNCT
fnp-3528	366	29	like	like	ADJ
fnp-3528	366	30	substrates	substrate	NOUN
fnp-3528	366	31	have	have	AUX
fnp-3528	366	32	attracted	attract	VERB
fnp-3528	366	33	attention	attention	NOUN
fnp-3528	366	34	,	,	PUNCT
fnp-3528	366	35	like	like	ADP
fnp-3528	366	36	sphingosine-1	sphingosine-1	ADV
fnp-3528	366	37	-	-	ADJ
fnp-3528	366	38	phosphate	phosphate	NOUN
fnp-3528	366	39	(	(	PUNCT
fnp-3528	366	40	abca1),229,496	abca1),229,496	NOUN
fnp-3528	366	41	α	α	NOUN
fnp-3528	366	42	-	-	NOUN
fnp-3528	366	43	tocopherol	tocopherol	NOUN
fnp-3528	366	44	(	(	PUNCT
fnp-3528	366	45	abca1),230	abca1),230	PROPN
fnp-3528	366	46	and	and	CCONJ
fnp-3528	366	47	atra	atra	PROPN
fnp-3528	366	48	(	(	PUNCT
fnp-3528	366	49	abca4).136	abca4).136	PROPN
fnp-3528	366	50	notably	notably	ADV
fnp-3528	366	51	,	,	PUNCT
fnp-3528	366	52	radiolabeled	radiolabele	VERB
fnp-3528	366	53	substrates	substrate	NOUN
fnp-3528	366	54	are	be	AUX
fnp-3528	366	55	very	very	ADV
fnp-3528	366	56	effective	effective	ADJ
fnp-3528	366	57	in	in	ADP
fnp-3528	366	58	terms	term	NOUN
fnp-3528	366	59	of	of	ADP
fnp-3528	366	60	accurate	accurate	ADJ
fnp-3528	366	61	tracing	tracing	NOUN
fnp-3528	366	62	of	of	ADP
fnp-3528	366	63	protein	protein	NOUN
fnp-3528	366	64	function	function	NOUN
fnp-3528	366	65	,	,	PUNCT
fnp-3528	366	66	as	as	SCONJ
fnp-3528	366	67	these	these	DET
fnp-3528	366	68	molecules	molecule	NOUN
fnp-3528	366	69	are	be	AUX
fnp-3528	366	70	not	not	PART
fnp-3528	366	71	changed	change	VERB
fnp-3528	366	72	in	in	ADP
fnp-3528	366	73	their	their	PRON
fnp-3528	366	74	molecular	molecular	ADJ
fnp-3528	366	75	integrity	integrity	NOUN
fnp-3528	366	76	in	in	ADP
fnp-3528	366	77	contrast	contrast	NOUN
fnp-3528	366	78	to	to	ADP
fnp-3528	366	79	fluorescence	fluorescence	NOUN
fnp-3528	366	80	probes.171,201,238,251,252,254,256,258,261,271,282,308,319,321,330,332,335,342,360,379,389,390,392,397,402,406,455,456,468	probes.171,201,238,251,252,254,256,258,261,271,282,308,319,321,330,332,335,342,360,379,389,390,392,397,402,406,455,456,468	NOUN
fnp-3528	366	81	,	,	PUNCT
fnp-3528	366	82	514	514	NUM
fnp-3528	366	83	-	-	SYM
fnp-3528	366	84	518	518	NUM
fnp-3528	366	85	on	on	ADP
fnp-3528	366	86	the	the	DET
fnp-3528	366	87	downside	downside	NOUN
fnp-3528	366	88	,	,	PUNCT
fnp-3528	366	89	conducting	conduct	VERB
fnp-3528	366	90	these	these	DET
fnp-3528	366	91	experiments	experiment	NOUN
fnp-3528	366	92	is	be	AUX
fnp-3528	366	93	constrained	constrain	VERB
fnp-3528	366	94	to	to	ADP
fnp-3528	366	95	regulatory	regulatory	ADJ
fnp-3528	366	96	requirements	requirement	NOUN
fnp-3528	366	97	and	and	CCONJ
fnp-3528	366	98	requires	require	VERB
fnp-3528	366	99	extensive	extensive	ADJ
fnp-3528	366	100	staff	staff	NOUN
fnp-3528	366	101	training	training	NOUN
fnp-3528	366	102	as	as	ADV
fnp-3528	366	103	well	well	ADV
fnp-3528	366	104	as	as	ADP
fnp-3528	366	105	expensive	expensive	ADJ
fnp-3528	366	106	safety	safety	NOUN
fnp-3528	366	107	measures	measure	NOUN
fnp-3528	366	108	and	and	CCONJ
fnp-3528	366	109	laboratory	laboratory	NOUN
fnp-3528	366	110	equipment	equipment	NOUN
fnp-3528	366	111	.	.	PUNCT
fnp-3528	367	1	fluorescent	fluorescent	ADJ
fnp-3528	367	2	tracers	tracer	NOUN
fnp-3528	367	3	of	of	ADP
fnp-3528	367	4	abca	abca	PROPN
fnp-3528	367	5	transport	transport	NOUN
fnp-3528	367	6	function	function	NOUN
fnp-3528	367	7	regarding	regard	VERB
fnp-3528	367	8	fluorescent	fluorescent	ADJ
fnp-3528	367	9	derivatives	derivative	NOUN
fnp-3528	367	10	of	of	ADP
fnp-3528	367	11	cholesterol	cholesterol	NOUN
fnp-3528	367	12	and	and	CCONJ
fnp-3528	367	13	phospholipids	phospholipid	NOUN
fnp-3528	367	14	,	,	PUNCT
fnp-3528	367	15	two	two	NUM
fnp-3528	367	16	major	major	ADJ
fnp-3528	367	17	types	type	NOUN
fnp-3528	367	18	can	can	AUX
fnp-3528	367	19	be	be	AUX
fnp-3528	367	20	differentiated	differentiate	VERB
fnp-3528	367	21	:	:	PUNCT
fnp-3528	367	22	(	(	PUNCT
fnp-3528	367	23	i	i	NOUN
fnp-3528	367	24	)	)	PUNCT
fnp-3528	367	25	7	7	NUM
fnp-3528	367	26	-	-	PUNCT
fnp-3528	367	27	nitro-2,1,3	nitro-2,1,3	ADJ
fnp-3528	367	28	-	-	PUNCT
fnp-3528	367	29	benzooxadiazole	benzooxadiazole	NOUN
fnp-3528	367	30	(	(	PUNCT
fnp-3528	367	31	nbd	nbd	PROPN
fnp-3528	367	32	)	)	PUNCT
fnp-3528	367	33	derivatives201,251,252,254,256,258,261,308,335,342,360,379,389,390,392,394,397,402	derivatives201,251,252,254,256,258,261,308,335,342,360,379,389,390,392,394,397,402	PROPN
fnp-3528	367	34	,	,	PUNCT
fnp-3528	367	35	406,408,468	406,408,468	NUM
fnp-3528	367	36	and	and	CCONJ
fnp-3528	367	37	(	(	PUNCT
fnp-3528	367	38	ii	ii	NOUN
fnp-3528	367	39	)	)	PUNCT
fnp-3528	367	40	4,4	4,4	NUM
fnp-3528	367	41	-	-	PUNCT
fnp-3528	367	42	difluoro-4	difluoro-4	NOUN
fnp-3528	367	43	-	-	PUNCT
fnp-3528	367	44	bora-3a,4a	bora-3a,4a	VERB
fnp-3528	367	45	-	-	PUNCT
fnp-3528	367	46	diaza	diaza	NOUN
fnp-3528	367	47	-	-	PUNCT
fnp-3528	367	48	s	s	NOUN
fnp-3528	367	49	-	-	PUNCT
fnp-3528	367	50	indacene	indacene	ADJ
fnp-3528	367	51	(	(	PUNCT
fnp-3528	367	52	bodipy	bodipy	NOUN
fnp-3528	367	53	)	)	PUNCT
fnp-3528	367	54	derivatives.271,282,319,321,330,332,455,456	derivatives.271,282,319,321,330,332,455,456	PROPN
fnp-3528	367	55	,	,	PUNCT
fnp-3528	367	56	515	515	NUM
fnp-3528	367	57	-	-	SYM
fnp-3528	367	58	517	517	NUM
fnp-3528	367	59	other	other	ADJ
fnp-3528	367	60	fluorophore	fluorophore	NOUN
fnp-3528	367	61	-	-	PUNCT
fnp-3528	367	62	labeled	label	VERB
fnp-3528	367	63	dyes	dye	NOUN
fnp-3528	367	64	have	have	AUX
fnp-3528	367	65	been	be	AUX
fnp-3528	367	66	reported	report	VERB
fnp-3528	367	67	,	,	PUNCT
fnp-3528	367	68	too	too	ADV
fnp-3528	367	69	,	,	PUNCT
fnp-3528	367	70	including	include	VERB
fnp-3528	367	71	the	the	DET
fnp-3528	367	72	sterane	sterane	NOUN
fnp-3528	367	73	analog	analog	NOUN
fnp-3528	367	74	dansyl	dansyl	NOUN
fnp-3528	367	75	-	-	PUNCT
fnp-3528	367	76	estramustine,171,238,518	estramustine,171,238,518	ADJ
fnp-3528	367	77	and	and	CCONJ
fnp-3528	367	78	propargyl	propargyl	PROPN
fnp-3528	367	79	choline	choline	NOUN
fnp-3528	367	80	,	,	PUNCT
fnp-3528	367	81	which	which	PRON
fnp-3528	367	82	is	be	AUX
fnp-3528	367	83	processed	process	VERB
fnp-3528	367	84	in	in	ADP
fnp-3528	367	85	vitro	vitro	X
fnp-3528	367	86	into	into	ADP
fnp-3528	367	87	propargylated	propargylate	VERB
fnp-3528	367	88	phospholipids.514	phospholipids.514	NOUN
fnp-3528	367	89	in	in	ADP
fnp-3528	367	90	addition	addition	NOUN
fnp-3528	367	91	to	to	ADP
fnp-3528	367	92	the	the	DET
fnp-3528	367	93	stated	state	VERB
fnp-3528	367	94	fluorescent	fluorescent	ADJ
fnp-3528	367	95	tracers	tracer	NOUN
fnp-3528	367	96	of	of	ADP
fnp-3528	367	97	abca	abca	PROPN
fnp-3528	367	98	transport	transport	NOUN
fnp-3528	367	99	function	function	NOUN
fnp-3528	367	100	,	,	PUNCT
fnp-3528	367	101	several	several	ADJ
fnp-3528	367	102	other	other	ADJ
fnp-3528	367	103	derivatives	derivative	NOUN
fnp-3528	367	104	of	of	ADP
fnp-3528	367	105	other	other	ADJ
fnp-3528	367	106	substrates	substrate	NOUN
fnp-3528	367	107	can	can	AUX
fnp-3528	367	108	be	be	AUX
fnp-3528	367	109	proposed	propose	VERB
fnp-3528	367	110	.	.	PUNCT
fnp-3528	368	1	for	for	ADP
fnp-3528	368	2	example	example	NOUN
fnp-3528	368	3	,	,	PUNCT
fnp-3528	368	4	n-3	n-3	ADJ
fnp-3528	368	5	-	-	PUNCT
fnp-3528	368	6	oxododecanoyl	oxododecanoyl	ADJ
fnp-3528	368	7	-	-	PUNCT
fnp-3528	368	8	l	l	NOUN
fnp-3528	368	9	-	-	PUNCT
fnp-3528	368	10	homoserine	homoserine	NOUN
fnp-3528	368	11	lactone	lactone	NOUN
fnp-3528	368	12	(	(	PUNCT
fnp-3528	368	13	3oc12	3oc12	PROPN
fnp-3528	368	14	-	-	PUNCT
fnp-3528	368	15	hsl	hsl	NOUN
fnp-3528	368	16	)	)	PUNCT
fnp-3528	368	17	was	be	AUX
fnp-3528	368	18	suggested	suggest	VERB
fnp-3528	368	19	as	as	ADP
fnp-3528	368	20	abca1	abca1	NOUN
fnp-3528	368	21	substrate	substrate	NOUN
fnp-3528	368	22	,	,	PUNCT
fnp-3528	368	23	but	but	CCONJ
fnp-3528	368	24	final	final	ADJ
fnp-3528	368	25	proof	proof	NOUN
fnp-3528	368	26	was	be	AUX
fnp-3528	368	27	missing.519	missing.519	PROPN
fnp-3528	368	28	thus	thus	ADV
fnp-3528	368	29	,	,	PUNCT
fnp-3528	368	30	it	it	PRON
fnp-3528	368	31	may	may	AUX
fnp-3528	368	32	be	be	AUX
fnp-3528	368	33	a	a	DET
fnp-3528	368	34	suitable	suitable	ADJ
fnp-3528	368	35	candidate	candidate	NOUN
fnp-3528	368	36	for	for	ADP
fnp-3528	368	37	validation	validation	NOUN
fnp-3528	368	38	in	in	ADP
fnp-3528	368	39	a	a	DET
fnp-3528	368	40	new	new	ADJ
fnp-3528	368	41	set	set	NOUN
fnp-3528	368	42	-	-	PUNCT
fnp-3528	368	43	up	up	NOUN
fnp-3528	368	44	in	in	ADP
fnp-3528	368	45	vitro	vitro	X
fnp-3528	368	46	assay	assay	PROPN
fnp-3528	368	47	for	for	ADP
fnp-3528	368	48	abca1	abca1	NOUN
fnp-3528	368	49	(	(	PUNCT
fnp-3528	368	50	and	and	CCONJ
fnp-3528	368	51	potentially	potentially	ADV
fnp-3528	368	52	other	other	ADJ
fnp-3528	368	53	abca	abca	NOUN
fnp-3528	368	54	transporters	transporter	NOUN
fnp-3528	368	55	)	)	PUNCT
fnp-3528	368	56	.	.	PUNCT
fnp-3528	369	1	other	other	ADJ
fnp-3528	369	2	examples	example	NOUN
fnp-3528	369	3	of	of	ADP
fnp-3528	369	4	potential	potential	ADJ
fnp-3528	369	5	probes	probe	NOUN
fnp-3528	369	6	are	be	AUX
fnp-3528	369	7	fluorescenct	fluorescenct	ADJ
fnp-3528	369	8	dyes	dye	NOUN
fnp-3528	369	9	that	that	PRON
fnp-3528	369	10	stand	stand	VERB
fnp-3528	369	11	in	in	ADP
fnp-3528	369	12	association	association	NOUN
fnp-3528	369	13	with	with	ADP
fnp-3528	369	14	cellular	cellular	ADJ
fnp-3528	369	15	cholesterol	cholesterol	NOUN
fnp-3528	369	16	and	and	CCONJ
fnp-3528	369	17	phospholipid	phospholipid	NOUN
fnp-3528	369	18	distribution	distribution	NOUN
fnp-3528	369	19	and	and	CCONJ
fnp-3528	369	20	abca1	abca1	NOUN
fnp-3528	369	21	-	-	PUNCT
fnp-3528	369	22	mediated	mediate	VERB
fnp-3528	369	23	cholesterol	cholesterol	NOUN
fnp-3528	369	24	and	and	CCONJ
fnp-3528	369	25	phospholipid	phospholipid	NOUN
fnp-3528	369	26	transport.516	transport.516	NOUN
fnp-3528	369	27	these	these	DET
fnp-3528	369	28	include	include	VERB
fnp-3528	369	29	,	,	PUNCT
fnp-3528	369	30	for	for	ADP
fnp-3528	369	31	example	example	NOUN
fnp-3528	369	32	,	,	PUNCT
fnp-3528	369	33	β	β	X
fnp-3528	369	34	bodipy	bodipy	NOUN
fnp-3528	369	35	fl	fl	PROPN
fnp-3528	369	36	c5	c5	PROPN
fnp-3528	369	37	-	-	PUNCT
fnp-3528	369	38	hpc	hpc	PROPN
fnp-3528	369	39	,	,	PUNCT
fnp-3528	369	40	β	β	NOUN
fnp-3528	369	41	-	-	PUNCT
fnp-3528	369	42	bodipy	bodipy	NOUN
fnp-3528	369	43	fl	fl	PROPN
fnp-3528	369	44	c12	c12	PROPN
fnp-3528	369	45	-	-	PUNCT
fnp-3528	369	46	hpc	hpc	NOUN
fnp-3528	369	47	,	,	PUNCT
fnp-3528	369	48	bodipy	bodipy	NOUN
fnp-3528	369	49	tr	tr	NOUN
fnp-3528	369	50	ceramide	ceramide	NOUN
fnp-3528	369	51	,	,	PUNCT
fnp-3528	369	52	and	and	CCONJ
fnp-3528	369	53	red	red	ADJ
fnp-3528	369	54	/	/	SYM
fnp-3528	369	55	green	green	ADJ
fnp-3528	369	56	bodipy	bodipy	NOUN
fnp-3528	369	57	pc	pc	NOUN
fnp-3528	369	58	-	-	PUNCT
fnp-3528	369	59	a2	a2	NOUN
fnp-3528	369	60	,	,	PUNCT
fnp-3528	369	61	amongst	amongst	ADP
fnp-3528	369	62	many	many	ADJ
fnp-3528	369	63	others.520	others.520	NOUN
fnp-3528	369	64	-	-	PUNCT
fnp-3528	369	65	522	522	NUM
fnp-3528	369	66	fluorescenct	fluorescenct	ADJ
fnp-3528	369	67	dyes	dye	NOUN
fnp-3528	369	68	are	be	AUX
fnp-3528	369	69	well	well	ADV
fnp-3528	369	70	-	-	PUNCT
fnp-3528	369	71	established	establish	VERB
fnp-3528	369	72	tracers	tracer	NOUN
fnp-3528	369	73	of	of	ADP
fnp-3528	369	74	abc	abc	PROPN
fnp-3528	369	75	transporter	transporter	PROPN
fnp-3528	369	76	function,18,19,23,24,284,480,488,489,493,507	function,18,19,23,24,284,480,488,489,493,507	NOUN
fnp-3528	369	77	,	,	PUNCT
fnp-3528	369	78	523	523	NUM
fnp-3528	369	79	-	-	SYM
fnp-3528	369	80	525	525	NUM
fnp-3528	369	81	and	and	CCONJ
fnp-3528	369	82	the	the	DET
fnp-3528	369	83	knowledge	knowledge	NOUN
fnp-3528	369	84	that	that	PRON
fnp-3528	369	85	has	have	AUX
fnp-3528	369	86	accumulated	accumulate	VERB
fnp-3528	369	87	regarding	regard	VERB
fnp-3528	369	88	the	the	DET
fnp-3528	369	89	well	well	ADV
fnp-3528	369	90	-	-	PUNCT
fnp-3528	369	91	studied	study	VERB
fnp-3528	369	92	abc	abc	PROPN
fnp-3528	369	93	transporters	transporter	NOUN
fnp-3528	369	94	abcb1	abcb1	PROPN
fnp-3528	369	95	,	,	PUNCT
fnp-3528	369	96	abcc1	abcc1	PROPN
fnp-3528	369	97	,	,	PUNCT
fnp-3528	369	98	and	and	CCONJ
fnp-3528	369	99	abcg2	abcg2	NOUN
fnp-3528	369	100	can	can	AUX
fnp-3528	369	101	be	be	AUX
fnp-3528	369	102	transferred	transfer	VERB
fnp-3528	369	103	to	to	ADP
fnp-3528	369	104	abca	abca	NOUN
fnp-3528	369	105	transporters	transporter	NOUN
fnp-3528	369	106	as	as	ADV
fnp-3528	369	107	well	well	ADV
fnp-3528	369	108	.	.	PUNCT
fnp-3528	370	1	however	however	ADV
fnp-3528	370	2	,	,	PUNCT
fnp-3528	370	3	the	the	DET
fnp-3528	370	4	added	add	VERB
fnp-3528	370	5	fluorophore	fluorophore	NOUN
fnp-3528	370	6	changes	change	VERB
fnp-3528	370	7	the	the	DET
fnp-3528	370	8	molecular	molecular	ADJ
fnp-3528	370	9	composition	composition	NOUN
fnp-3528	370	10	of	of	ADP
fnp-3528	370	11	the	the	DET
fnp-3528	370	12	tracing	trace	VERB
fnp-3528	370	13	molecules	molecule	NOUN
fnp-3528	370	14	.	.	PUNCT
fnp-3528	371	1	this	this	DET
fnp-3528	371	2	alteration	alteration	NOUN
fnp-3528	371	3	inheres	inhere	VERB
fnp-3528	371	4	the	the	DET
fnp-3528	371	5	potential	potential	ADJ
fnp-3528	371	6	risk	risk	NOUN
fnp-3528	371	7	of	of	ADP
fnp-3528	371	8	changing	change	VERB
fnp-3528	371	9	affinities	affinity	NOUN
fnp-3528	371	10	and	and	CCONJ
fnp-3528	371	11	even	even	ADV
fnp-3528	371	12	the	the	DET
fnp-3528	371	13	binding	bind	VERB
fnp-3528	371	14	site(s	site(s	NOUN
fnp-3528	371	15	)	)	PUNCT
fnp-3528	371	16	of	of	ADP
fnp-3528	371	17	these	these	DET
fnp-3528	371	18	molecules	molecule	NOUN
fnp-3528	371	19	,	,	PUNCT
fnp-3528	371	20	undermining	undermine	VERB
fnp-3528	371	21	functional	functional	ADJ
fnp-3528	371	22	-	-	PUNCT
fnp-3528	371	23	kinetic	kinetic	ADJ
fnp-3528	371	24	analyses	analysis	NOUN
fnp-3528	371	25	regarding	regard	VERB
fnp-3528	371	26	binding	bind	VERB
fnp-3528	371	27	site	site	NOUN
fnp-3528	371	28	determination	determination	NOUN
fnp-3528	371	29	and	and	CCONJ
fnp-3528	371	30	elucidation	elucidation	NOUN
fnp-3528	371	31	of	of	ADP
fnp-3528	371	32	the	the	DET
fnp-3528	371	33	mode	mode	NOUN
fnp-3528	371	34	of	of	ADP
fnp-3528	371	35	action	action	NOUN
fnp-3528	371	36	.	.	PUNCT
fnp-3528	372	1	nevertheless	nevertheless	ADV
fnp-3528	372	2	,	,	PUNCT
fnp-3528	372	3	fluorescence	fluorescence	NOUN
fnp-3528	372	4	probes	probe	NOUN
fnp-3528	372	5	are	be	AUX
fnp-3528	372	6	–	–	PUNCT
fnp-3528	372	7	if	if	SCONJ
fnp-3528	372	8	used	use	VERB
fnp-3528	372	9	and	and	CCONJ
fnp-3528	372	10	established	establish	VERB
fnp-3528	372	11	correctly	correctly	ADV
fnp-3528	372	12	–	–	PUNCT
fnp-3528	372	13	extremely	extremely	ADV
fnp-3528	372	14	reliable	reliable	ADJ
fnp-3528	372	15	,	,	PUNCT
fnp-3528	372	16	and	and	CCONJ
fnp-3528	372	17	can	can	AUX
fnp-3528	372	18	be	be	AUX
fnp-3528	372	19	used	use	VERB
fnp-3528	372	20	without	without	ADP
fnp-3528	372	21	regulatory	regulatory	ADJ
fnp-3528	372	22	restrictions	restriction	NOUN
fnp-3528	372	23	and	and	CCONJ
fnp-3528	372	24	necessity	necessity	NOUN
fnp-3528	372	25	of	of	ADP
fnp-3528	372	26	special	special	ADJ
fnp-3528	372	27	equipment	equipment	NOUN
fnp-3528	372	28	,	,	PUNCT
fnp-3528	372	29	except	except	SCONJ
fnp-3528	372	30	for	for	ADP
fnp-3528	372	31	microplate	microplate	NOUN
fnp-3528	372	32	readers	reader	NOUN
fnp-3528	372	33	and/or	and/or	CCONJ
fnp-3528	372	34	flow	flow	NOUN
fnp-3528	372	35	cytometers	cytometer	NOUN
fnp-3528	372	36	.	.	PUNCT
fnp-3528	373	1	colorimetric	colorimetric	ADJ
fnp-3528	373	2	determination	determination	NOUN
fnp-3528	373	3	of	of	ADP
fnp-3528	373	4	abca	abca	PROPN
fnp-3528	373	5	transport	transport	NOUN
fnp-3528	373	6	function	function	NOUN
fnp-3528	373	7	–	–	PUNCT
fnp-3528	373	8	atpase	atpase	NOUN
fnp-3528	373	9	assays	assay	NOUN
fnp-3528	373	10	as	as	SCONJ
fnp-3528	373	11	mentioned	mention	VERB
fnp-3528	373	12	above	above	ADV
fnp-3528	373	13	,	,	PUNCT
fnp-3528	373	14	atpase	atpase	PROPN
fnp-3528	373	15	assays	assay	NOUN
fnp-3528	373	16	have	have	AUX
fnp-3528	373	17	also	also	ADV
fnp-3528	373	18	been	be	AUX
fnp-3528	373	19	used	use	VERB
fnp-3528	373	20	to	to	PART
fnp-3528	373	21	functionally	functionally	ADV
fnp-3528	373	22	analyze	analyze	VERB
fnp-3528	373	23	abca	abca	NOUN
fnp-3528	373	24	transporter	transporter	NOUN
fnp-3528	373	25	function	function	NOUN
fnp-3528	373	26	,	,	PUNCT
fnp-3528	373	27	in	in	ADP
fnp-3528	373	28	particular	particular	ADJ
fnp-3528	373	29	for	for	ADP
fnp-3528	373	30	abca1,201,499,505,506	abca1,201,499,505,506	NOUN
fnp-3528	373	31	abca2,500	abca2,500	PROPN
fnp-3528	373	32	abca3139,504	abca3139,504	VERB
fnp-3528	373	33	abca4,133	abca4,133	PROPN
fnp-3528	373	34	-	-	PROPN
fnp-3528	373	35	135,137,138,201,501,502	135,137,138,201,501,502	PROPN
fnp-3528	373	36	and	and	CCONJ
fnp-3528	373	37	abca7,201	abca7,201	VERB
fnp-3528	373	38	although	although	SCONJ
fnp-3528	373	39	this	this	DET
fnp-3528	373	40	methodology	methodology	NOUN
fnp-3528	373	41	has	have	AUX
fnp-3528	373	42	been	be	AUX
fnp-3528	373	43	used	use	VERB
fnp-3528	373	44	somewhat	somewhat	ADV
fnp-3528	373	45	rarely	rarely	ADV
fnp-3528	373	46	compared	compare	VERB
fnp-3528	373	47	to	to	ADP
fnp-3528	373	48	other	other	ADJ
fnp-3528	373	49	functional	functional	ADJ
fnp-3528	373	50	approaches	approach	NOUN
fnp-3528	373	51	.	.	PUNCT
fnp-3528	374	1	atpase	atpase	PROPN
fnp-3528	374	2	assays	assay	NOUN
fnp-3528	374	3	are	be	AUX
fnp-3528	374	4	based	base	VERB
fnp-3528	374	5	on	on	ADP
fnp-3528	374	6	the	the	DET
fnp-3528	374	7	principle	principle	NOUN
fnp-3528	374	8	that	that	SCONJ
fnp-3528	374	9	the	the	DET
fnp-3528	374	10	active	active	ADJ
fnp-3528	374	11	transport	transport	NOUN
fnp-3528	374	12	of	of	ADP
fnp-3528	374	13	any	any	DET
fnp-3528	374	14	substrate	substrate	NOUN
fnp-3528	374	15	of	of	ADP
fnp-3528	374	16	abc	abc	PROPN
fnp-3528	374	17	transporters	transporter	NOUN
fnp-3528	374	18	consumes	consume	VERB
fnp-3528	374	19	energy	energy	NOUN
fnp-3528	374	20	.	.	PUNCT
fnp-3528	375	1	this	this	DET
fnp-3528	375	2	energy	energy	NOUN
fnp-3528	375	3	is	be	AUX
fnp-3528	375	4	derived	derive	VERB
fnp-3528	375	5	from	from	ADP
fnp-3528	375	6	the	the	DET
fnp-3528	375	7	cleavage	cleavage	NOUN
fnp-3528	375	8	of	of	ADP
fnp-3528	375	9	atp	atp	PROPN
fnp-3528	375	10	to	to	ADP
fnp-3528	375	11	adp	adp	PROPN
fnp-3528	375	12	and	and	CCONJ
fnp-3528	375	13	pi	pi	NOUN
fnp-3528	375	14	,	,	PUNCT
fnp-3528	375	15	and	and	CCONJ
fnp-3528	375	16	can	can	AUX
fnp-3528	375	17	be	be	AUX
fnp-3528	375	18	detected	detect	VERB
fnp-3528	375	19	by	by	ADP
fnp-3528	375	20	different	different	ADJ
fnp-3528	375	21	methodologies.23,24,507	methodologies.23,24,507	PROPN
fnp-3528	375	22	-	-	PUNCT
fnp-3528	375	23	510,526	510,526	NUM
fnp-3528	375	24	table	table	NOUN
fnp-3528	375	25	 	 	SPACE
fnp-3528	375	26	5	5	NUM
fnp-3528	375	27	highlights	highlight	NOUN
fnp-3528	375	28	known	know	VERB
fnp-3528	375	29	atpase	atpase	NOUN
fnp-3528	375	30	modulators	modulator	NOUN
fnp-3528	375	31	of	of	ADP
fnp-3528	375	32	abca	abca	NOUN
fnp-3528	375	33	transporters	transporter	NOUN
fnp-3528	375	34	and	and	CCONJ
fnp-3528	375	35	the	the	DET
fnp-3528	375	36	associated	associated	ADJ
fnp-3528	375	37	literature	literature	NOUN
fnp-3528	375	38	reports	report	NOUN
fnp-3528	375	39	.	.	PUNCT
fnp-3528	376	1	table	table	NOUN
fnp-3528	376	2	5	5	NUM
fnp-3528	376	3	.	.	PUNCT
fnp-3528	377	1	summary	summary	NOUN
fnp-3528	377	2	of	of	ADP
fnp-3528	377	3	known	know	VERB
fnp-3528	377	4	atpase	atpase	NOUN
fnp-3528	377	5	modulators	modulator	NOUN
fnp-3528	377	6	of	of	ADP
fnp-3528	377	7	abca	abca	NOUN
fnp-3528	377	8	transporters	transporter	NOUN
fnp-3528	377	9	.	.	PUNCT
fnp-3528	378	1	transporter	transporter	NOUN
fnp-3528	378	2	modulator	modulator	NOUN
fnp-3528	378	3	mode	mode	NOUN
fnp-3528	378	4	of	of	ADP
fnp-3528	378	5	modulation	modulation	NOUN
fnp-3528	378	6	references	reference	NOUN
fnp-3528	378	7	abca1	abca1	NOUN
fnp-3528	378	8	ceramide	ceramide	NOUN
fnp-3528	378	9	(	(	PUNCT
fnp-3528	378	10	30	30	NUM
fnp-3528	378	11	mol–%	mol–%	NUM
fnp-3528	378	12	)	)	PUNCT
fnp-3528	378	13	cholesterol	cholesterol	NOUN
fnp-3528	378	14	(	(	PUNCT
fnp-3528	378	15	30	30	NUM
fnp-3528	378	16	mol–%	mol–%	NUM
fnp-3528	378	17	)	)	PUNCT
fnp-3528	378	18	phosphatidylcholine	phosphatidylcholine	NOUN
fnp-3528	378	19	(	(	PUNCT
fnp-3528	378	20	30	30	NUM
fnp-3528	378	21	mol–%	mol–%	NUM
fnp-3528	378	22	)	)	PUNCT
fnp-3528	378	23	phosphatidylethanolamine	phosphatidylethanolamine	NOUN
fnp-3528	378	24	(	(	PUNCT
fnp-3528	378	25	30	30	NUM
fnp-3528	378	26	mol–%	mol–%	NUM
fnp-3528	378	27	)	)	PUNCT
fnp-3528	378	28	phosphatidylinositol	phosphatidylinositol	NOUN
fnp-3528	378	29	(	(	PUNCT
fnp-3528	378	30	30	30	NUM
fnp-3528	378	31	mol–%	mol–%	NUM
fnp-3528	378	32	)	)	PUNCT
fnp-3528	378	33	phosphatidylserine	phosphatidylserine	NOUN
fnp-3528	378	34	(	(	PUNCT
fnp-3528	378	35	30	30	NUM
fnp-3528	378	36	mol–%	mol–%	NUM
fnp-3528	378	37	)	)	PUNCT
fnp-3528	378	38	sphingomyelin	sphingomyelin	NOUN
fnp-3528	378	39	(	(	PUNCT
fnp-3528	378	40	30	30	NUM
fnp-3528	378	41	mol–%	mol–%	NUM
fnp-3528	378	42	)	)	PUNCT
fnp-3528	378	43	inhibition	inhibition	NOUN
fnp-3528	378	44	inhibition	inhibition	NOUN
fnp-3528	378	45	activation	activation	NOUN
fnp-3528	378	46	inhibition	inhibition	NOUN
fnp-3528	378	47	inhibition	inhibition	NOUN
fnp-3528	378	48	activation	activation	NOUN
fnp-3528	378	49	activation	activation	NOUN
fnp-3528	378	50	201	201	NUM
fnp-3528	378	51	201,499	201,499	NUM
fnp-3528	378	52	201	201	NUM
fnp-3528	378	53	201	201	NUM
fnp-3528	378	54	201	201	NUM
fnp-3528	378	55	201	201	NUM
fnp-3528	378	56	201	201	NUM
fnp-3528	378	57	abca2	abca2	NOUN
fnp-3528	378	58	methyl	methyl	NOUN
fnp-3528	378	59	-	-	PUNCT
fnp-3528	378	60	β	β	NOUN
fnp-3528	378	61	-	-	NOUN
fnp-3528	378	62	cyclodextrin	cyclodextrin	NOUN
fnp-3528	378	63	(	(	PUNCT
fnp-3528	378	64	u.c.a	u.c.a	NOUN
fnp-3528	378	65	)	)	PUNCT
fnp-3528	378	66	activation	activation	NOUN
fnp-3528	378	67	500	500	NUM
fnp-3528	378	68	abca4	abca4	NOUN
fnp-3528	379	1	amiodarone	amiodarone	NOUN
fnp-3528	379	2	(	(	PUNCT
fnp-3528	379	3	20–75	20–75	NUM
fnp-3528	379	4	µm	µm	NOUN
fnp-3528	379	5	)	)	PUNCT
fnp-3528	379	6	2	2	NUM
fnp-3528	379	7	-	-	PUNCT
fnp-3528	379	8	tert	tert	NOUN
fnp-3528	379	9	-	-	PUNCT
fnp-3528	379	10	butylanthraquinone	butylanthraquinone	NOUN
fnp-3528	379	11	(	(	PUNCT
fnp-3528	379	12	20–50	20–50	NUM
fnp-3528	379	13	µm	µm	NOUN
fnp-3528	379	14	)	)	PUNCT
fnp-3528	379	15	ceramide	ceramide	NOUN
fnp-3528	379	16	(	(	PUNCT
fnp-3528	379	17	30	30	NUM
fnp-3528	379	18	mol–%	mol–%	NUM
fnp-3528	379	19	)	)	PUNCT
fnp-3528	379	20	cholesterol	cholesterol	NOUN
fnp-3528	379	21	(	(	PUNCT
fnp-3528	379	22	30	30	NUM
fnp-3528	379	23	mol–%	mol–%	NUM
fnp-3528	379	24	)	)	PUNCT
fnp-3528	379	25	dehydroabietylacetate	dehydroabietylacetate	NOUN
fnp-3528	379	26	(	(	PUNCT
fnp-3528	379	27	10–50	10–50	NUM
fnp-3528	379	28	µm	µm	NOUN
fnp-3528	379	29	)	)	PUNCT
fnp-3528	379	30	digitonin	digitonin	NOUN
fnp-3528	379	31	(	(	PUNCT
fnp-3528	379	32	10–180	10–180	NUM
fnp-3528	379	33	µm	µm	NOUN
fnp-3528	379	34	)	)	PUNCT
fnp-3528	379	35	n	n	CCONJ
fnp-3528	379	36	-	-	PUNCT
fnp-3528	379	37	ethylmaleimide	ethylmaleimide	X
fnp-3528	379	38	(	(	PUNCT
fnp-3528	379	39	nem	nem	PROPN
fnp-3528	379	40	;	;	PUNCT
fnp-3528	379	41	1000	1000	NUM
fnp-3528	379	42	µm	µm	NOUN
fnp-3528	379	43	)	)	PUNCT
fnp-3528	379	44	reduced	reduced	ADJ
fnp-3528	379	45	glutathione	glutathione	NOUN
fnp-3528	379	46	(	(	PUNCT
fnp-3528	379	47	gsh	gsh	PROPN
fnp-3528	379	48	;	;	PUNCT
fnp-3528	379	49	1000	1000	NUM
fnp-3528	379	50	µm	µm	NOUN
fnp-3528	379	51	)	)	PUNCT
fnp-3528	379	52	β	β	NOUN
fnp-3528	379	53	-	-	PUNCT
fnp-3528	379	54	ionone	ionone	NOUN
fnp-3528	379	55	(	(	PUNCT
fnp-3528	379	56	50–100	50–100	NUM
fnp-3528	379	57	µm	µm	NOUN
fnp-3528	379	58	)	)	PUNCT
fnp-3528	379	59	phosphatidylethanolamine	phosphatidylethanolamine	NOUN
fnp-3528	379	60	(	(	PUNCT
fnp-3528	379	61	30	30	NUM
fnp-3528	379	62	mol–%	mol–%	NUM
fnp-3528	379	63	)	)	PUNCT
fnp-3528	379	64	phosphatidylglycerol	phosphatidylglycerol	NOUN
fnp-3528	379	65	(	(	PUNCT
fnp-3528	379	66	30	30	NUM
fnp-3528	379	67	mol–%	mol–%	NUM
fnp-3528	379	68	)	)	PUNCT
fnp-3528	379	69	phosphtidylinositol	phosphtidylinositol	NOUN
fnp-3528	379	70	(	(	PUNCT
fnp-3528	379	71	30	30	NUM
fnp-3528	379	72	mol–%	mol–%	NUM
fnp-3528	379	73	)	)	PUNCT
fnp-3528	379	74	11	11	NUM
fnp-3528	379	75	-	-	PUNCT
fnp-3528	379	76	cis	cis	NOUN
fnp-3528	379	77	-	-	PUNCT
fnp-3528	379	78	retinal	retinal	ADJ
fnp-3528	379	79	(	(	PUNCT
fnp-3528	379	80	5–100	5–100	NUM
fnp-3528	379	81	µm	µm	NOUN
fnp-3528	379	82	)	)	PUNCT
fnp-3528	379	83	13	13	NUM
fnp-3528	379	84	-	-	PUNCT
fnp-3528	379	85	cis	cis	NOUN
fnp-3528	379	86	-	-	PUNCT
fnp-3528	379	87	retinal	retinal	ADJ
fnp-3528	379	88	(	(	PUNCT
fnp-3528	379	89	5–100	5–100	NUM
fnp-3528	379	90	µm	µm	NOUN
fnp-3528	379	91	)	)	PUNCT
fnp-3528	379	92	atra	atra	NOUN
fnp-3528	379	93	(	(	PUNCT
fnp-3528	379	94	5–100	5–100	NUM
fnp-3528	379	95	µm	µm	NOUN
fnp-3528	379	96	;	;	PUNCT
fnp-3528	380	1	ec50	ec50	PROPN
fnp-3528	380	2	=	=	PROPN
fnp-3528	380	3	10	10	NUM
fnp-3528	380	4	µm	µm	NOUN
fnp-3528	380	5	)	)	PUNCT
fnp-3528	380	6	all	all	DET
fnp-3528	380	7	-	-	PUNCT
fnp-3528	380	8	trans	trans	ADJ
fnp-3528	380	9	-	-	ADJ
fnp-3528	380	10	retinoic	retinoic	ADJ
fnp-3528	380	11	acid	acid	NOUN
fnp-3528	380	12	(	(	PUNCT
fnp-3528	380	13	20–100	20–100	PROPN
fnp-3528	380	14	µm	µm	NOUN
fnp-3528	380	15	)	)	PUNCT
fnp-3528	380	16	all	all	DET
fnp-3528	380	17	-	-	PUNCT
fnp-3528	380	18	trans	trans	NOUN
fnp-3528	380	19	-	-	NOUN
fnp-3528	380	20	retinol	retinol	NOUN
fnp-3528	380	21	(	(	PUNCT
fnp-3528	380	22	20–100	20–100	PROPN
fnp-3528	380	23	µm	µm	NOUN
fnp-3528	380	24	)	)	PUNCT
fnp-3528	380	25	n	n	CCONJ
fnp-3528	380	26	-	-	PUNCT
fnp-3528	380	27	retinylidenephosphatidylethanolamine	retinylidenephosphatidylethanolamine	NOUN
fnp-3528	380	28	(	(	PUNCT
fnp-3528	380	29	40	40	NUM
fnp-3528	380	30	µm	µm	NOUN
fnp-3528	380	31	)	)	PUNCT
fnp-3528	380	32	activation	activation	NOUN
fnp-3528	380	33	activation	activation	NOUN
fnp-3528	380	34	inhibition	inhibition	NOUN
fnp-3528	380	35	inhibition	inhibition	NOUN
fnp-3528	380	36	activation	activation	NOUN
fnp-3528	380	37	activation	activation	NOUN
fnp-3528	380	38	inhibition	inhibition	NOUN
fnp-3528	380	39	activation	activation	NOUN
fnp-3528	380	40	activation	activation	NOUN
fnp-3528	380	41	activation	activation	NOUN
fnp-3528	380	42	activation	activation	NOUN
fnp-3528	380	43	inhibition	inhibition	NOUN
fnp-3528	380	44	activation	activation	NOUN
fnp-3528	380	45	activation	activation	NOUN
fnp-3528	380	46	activation	activation	NOUN
fnp-3528	380	47	activation	activation	NOUN
fnp-3528	380	48	activation	activation	NOUN
fnp-3528	380	49	activation	activation	NOUN
fnp-3528	380	50	138	138	NUM
fnp-3528	380	51	138	138	NUM
fnp-3528	380	52	201	201	NUM
fnp-3528	380	53	201	201	NUM
fnp-3528	380	54	138	138	NUM
fnp-3528	380	55	138	138	NUM
fnp-3528	380	56	137	137	NUM
fnp-3528	380	57	137	137	NUM
fnp-3528	380	58	138	138	NUM
fnp-3528	380	59	201	201	NUM
fnp-3528	380	60	201	201	NUM
fnp-3528	380	61	201	201	NUM
fnp-3528	380	62	137,138	137,138	NUM
fnp-3528	380	63	138	138	NUM
fnp-3528	380	64	133	133	NUM
fnp-3528	380	65	-	-	SYM
fnp-3528	380	66	135,137,138	135,137,138	NUM
fnp-3528	380	67	138	138	NUM
fnp-3528	380	68	133,138	133,138	NUM
fnp-3528	380	69	133	133	NUM
fnp-3528	380	70	abca7	abca7	NOUN
fnp-3528	380	71	ceramide	ceramide	NOUN
fnp-3528	380	72	(	(	PUNCT
fnp-3528	380	73	30	30	NUM
fnp-3528	380	74	mol–%	mol–%	NUM
fnp-3528	380	75	)	)	PUNCT
fnp-3528	380	76	cholesterol	cholesterol	NOUN
fnp-3528	380	77	(	(	PUNCT
fnp-3528	380	78	30	30	NUM
fnp-3528	380	79	mol–%	mol–%	NUM
fnp-3528	380	80	)	)	PUNCT
fnp-3528	380	81	phosphatidylcholine	phosphatidylcholine	NOUN
fnp-3528	380	82	(	(	PUNCT
fnp-3528	380	83	30	30	NUM
fnp-3528	380	84	mol–%	mol–%	NUM
fnp-3528	380	85	)	)	PUNCT
fnp-3528	380	86	phosphatidylethanolamine	phosphatidylethanolamine	NOUN
fnp-3528	380	87	(	(	PUNCT
fnp-3528	380	88	30	30	NUM
fnp-3528	380	89	mol–%	mol–%	NUM
fnp-3528	380	90	)	)	PUNCT
fnp-3528	380	91	phosphatidylserine	phosphatidylserine	NOUN
fnp-3528	380	92	(	(	PUNCT
fnp-3528	380	93	30	30	NUM
fnp-3528	380	94	mol–%	mol–%	NUM
fnp-3528	380	95	)	)	PUNCT
fnp-3528	380	96	inhibition	inhibition	NOUN
fnp-3528	380	97	inhibition	inhibition	NOUN
fnp-3528	380	98	activation	activation	NOUN
fnp-3528	380	99	activation	activation	NOUN
fnp-3528	380	100	activation	activation	NOUN
fnp-3528	380	101	201	201	NUM
fnp-3528	380	102	201	201	NUM
fnp-3528	380	103	201	201	NUM
fnp-3528	380	104	201	201	NUM
fnp-3528	380	105	201	201	NUM
fnp-3528	380	106	a	a	DET
fnp-3528	380	107	u.c	u.c	PROPN
fnp-3528	380	108	.	.	PUNCT
fnp-3528	380	109	=	=	SYM
fnp-3528	381	1	unspecified	unspecified	ADJ
fnp-3528	381	2	concentration	concentration	NOUN
fnp-3528	381	3	atpase	atpase	PROPN
fnp-3528	381	4	assays	assay	NOUN
fnp-3528	381	5	have	have	AUX
fnp-3528	381	6	been	be	AUX
fnp-3528	381	7	and	and	CCONJ
fnp-3528	381	8	still	still	ADV
fnp-3528	381	9	are	be	AUX
fnp-3528	381	10	popular	popular	ADJ
fnp-3528	381	11	in	in	ADP
fnp-3528	381	12	terms	term	NOUN
fnp-3528	381	13	of	of	ADP
fnp-3528	381	14	functional	functional	ADJ
fnp-3528	381	15	abc	abc	PROPN
fnp-3528	381	16	transporter	transporter	NOUN
fnp-3528	381	17	modulation	modulation	NOUN
fnp-3528	381	18	in	in	ADP
fnp-3528	381	19	general.23,24,507	general.23,24,507	NOUN
fnp-3528	381	20	-	-	ADJ
fnp-3528	381	21	510	510	NUM
fnp-3528	381	22	strikingly	strikingly	ADV
fnp-3528	381	23	,	,	PUNCT
fnp-3528	381	24	the	the	DET
fnp-3528	381	25	nbds	nbds	NOUN
fnp-3528	381	26	of	of	ADP
fnp-3528	381	27	abc	abc	PROPN
fnp-3528	381	28	transporters	transporter	NOUN
fnp-3528	381	29	are	be	AUX
fnp-3528	381	30	–	–	PUNCT
fnp-3528	381	31	in	in	ADP
fnp-3528	381	32	contrast	contrast	NOUN
fnp-3528	381	33	to	to	ADP
fnp-3528	381	34	the	the	DET
fnp-3528	381	35	various	various	ADJ
fnp-3528	381	36	binding	bind	VERB
fnp-3528	381	37	sites	site	NOUN
fnp-3528	381	38	identified	identify	VERB
fnp-3528	381	39	within	within	ADP
fnp-3528	381	40	the	the	DET
fnp-3528	381	41	transmembrane	transmembrane	NOUN
fnp-3528	381	42	domains	domain	NOUN
fnp-3528	381	43	of	of	ADP
fnp-3528	381	44	abc	abc	PROPN
fnp-3528	381	45	transporters475	transporters475	PROPN
fnp-3528	381	46	–	–	PUNCT
fnp-3528	381	47	highly	highly	ADV
fnp-3528	381	48	conserved	conserved	ADJ
fnp-3528	381	49	.	.	PUNCT
fnp-3528	382	1	this	this	DET
fnp-3528	382	2	conservation	conservation	NOUN
fnp-3528	382	3	enables	enable	VERB
fnp-3528	382	4	targeting	target	VERB
fnp-3528	382	5	of	of	ADP
fnp-3528	382	6	abca	abca	PROPN
fnp-3528	382	7	nbds	nbds	NOUN
fnp-3528	382	8	by	by	ADP
fnp-3528	382	9	known	know	VERB
fnp-3528	382	10	atpase	atpase	NOUN
fnp-3528	382	11	modulators	modulator	NOUN
fnp-3528	382	12	of	of	ADP
fnp-3528	382	13	other	other	ADJ
fnp-3528	382	14	abc	abc	PROPN
fnp-3528	382	15	transporters	transporter	NOUN
fnp-3528	382	16	.	.	PUNCT
fnp-3528	383	1	therefore	therefore	ADV
fnp-3528	383	2	,	,	PUNCT
fnp-3528	383	3	abca	abca	NOUN
fnp-3528	383	4	transporter	transporter	NOUN
fnp-3528	383	5	function	function	NOUN
fnp-3528	383	6	can	can	AUX
fnp-3528	383	7	be	be	AUX
fnp-3528	383	8	detected	detect	VERB
fnp-3528	383	9	by	by	ADP
fnp-3528	383	10	methodologies	methodology	NOUN
fnp-3528	383	11	that	that	PRON
fnp-3528	383	12	have	have	AUX
fnp-3528	383	13	already	already	ADV
fnp-3528	383	14	been	be	AUX
fnp-3528	383	15	established	establish	VERB
fnp-3528	383	16	for	for	ADP
fnp-3528	383	17	other	other	ADJ
fnp-3528	383	18	abc	abc	PROPN
fnp-3528	383	19	transporters.23,24,507	transporters.23,24,507	PROPN
fnp-3528	383	20	-	-	PUNCT
fnp-3528	383	21	510,526	510,526	NUM
fnp-3528	383	22	this	this	DET
fnp-3528	383	23	transfer	transfer	NOUN
fnp-3528	383	24	of	of	ADP
fnp-3528	383	25	knowledge	knowledge	NOUN
fnp-3528	383	26	will	will	AUX
fnp-3528	383	27	be	be	AUX
fnp-3528	383	28	of	of	ADP
fnp-3528	383	29	great	great	ADJ
fnp-3528	383	30	use	use	NOUN
fnp-3528	383	31	to	to	PART
fnp-3528	383	32	confirm	confirm	VERB
fnp-3528	383	33	obtained	obtain	VERB
fnp-3528	383	34	results	result	NOUN
fnp-3528	383	35	from	from	ADP
fnp-3528	383	36	other	other	ADJ
fnp-3528	383	37	functional	functional	ADJ
fnp-3528	383	38	abca	abca	NOUN
fnp-3528	383	39	transporter	transporter	NOUN
fnp-3528	383	40	analyses	analysis	NOUN
fnp-3528	383	41	.	.	PUNCT
fnp-3528	384	1	colorimetric	colorimetric	ADJ
fnp-3528	384	2	determination	determination	NOUN
fnp-3528	384	3	of	of	ADP
fnp-3528	384	4	abca	abca	PROPN
fnp-3528	384	5	transport	transport	NOUN
fnp-3528	384	6	function	function	NOUN
fnp-3528	384	7	–	–	PUNCT
fnp-3528	384	8	other	other	ADJ
fnp-3528	384	9	detection	detection	NOUN
fnp-3528	384	10	methodologies	methodology	NOUN
fnp-3528	384	11	as	as	ADP
fnp-3528	384	12	a	a	DET
fnp-3528	384	13	final	final	ADJ
fnp-3528	384	14	note	note	NOUN
fnp-3528	384	15	,	,	PUNCT
fnp-3528	384	16	it	it	PRON
fnp-3528	384	17	must	must	AUX
fnp-3528	384	18	be	be	AUX
fnp-3528	384	19	mentioned	mention	VERB
fnp-3528	384	20	that	that	SCONJ
fnp-3528	384	21	other	other	ADJ
fnp-3528	384	22	colorimetric	colorimetric	ADJ
fnp-3528	384	23	analyses	analysis	NOUN
fnp-3528	384	24	were	be	AUX
fnp-3528	384	25	also	also	ADV
fnp-3528	384	26	used	use	VERB
fnp-3528	384	27	to	to	PART
fnp-3528	384	28	quantify	quantify	VERB
fnp-3528	384	29	the	the	DET
fnp-3528	384	30	abca	abca	ADJ
fnp-3528	384	31	transporter	transporter	NOUN
fnp-3528	384	32	-	-	PUNCT
fnp-3528	384	33	mediated	mediate	VERB
fnp-3528	384	34	function	function	NOUN
fnp-3528	384	35	,	,	PUNCT
fnp-3528	384	36	specifically	specifically	ADV
fnp-3528	384	37	for	for	ADP
fnp-3528	384	38	transport	transport	NOUN
fnp-3528	384	39	of	of	ADP
fnp-3528	384	40	cholesterol	cholesterol	NOUN
fnp-3528	384	41	or	or	CCONJ
fnp-3528	384	42	choline	choline	NOUN
fnp-3528	384	43	-	-	PUNCT
fnp-3528	384	44	containing	contain	VERB
fnp-3528	384	45	lipids	lipid	NOUN
fnp-3528	384	46	,	,	PUNCT
fnp-3528	384	47	using	use	VERB
fnp-3528	384	48	commercially	commercially	ADV
fnp-3528	384	49	available	available	ADJ
fnp-3528	384	50	assay	assay	ADP
fnp-3528	384	51	kits.202,205,246,251,268,272,275,329	kits.202,205,246,251,268,272,275,329	PROPN
fnp-3528	384	52	-	-	PUNCT
fnp-3528	384	53	332,334,336,354,365,366,369,372,374	332,334,336,354,365,366,369,372,374	NUM
fnp-3528	384	54	-	-	NUM
fnp-3528	384	55	376,386	376,386	NUM
fnp-3528	384	56	-	-	PUNCT
fnp-3528	384	57	389,392,405	389,392,405	NUM
fnp-3528	384	58	,	,	PUNCT
fnp-3528	384	59	406,416,418,421,422,424,425,441,511	406,416,418,421,422,424,425,441,511	PROPN
fnp-3528	384	60	however	however	ADV
fnp-3528	384	61	,	,	PUNCT
fnp-3528	384	62	these	these	DET
fnp-3528	384	63	methodologies	methodology	NOUN
fnp-3528	384	64	require	require	VERB
fnp-3528	384	65	time	time	NOUN
fnp-3528	384	66	-	-	PUNCT
fnp-3528	384	67	consuming	consume	VERB
fnp-3528	384	68	extraction	extraction	NOUN
fnp-3528	384	69	processes	process	NOUN
fnp-3528	384	70	of	of	ADP
fnp-3528	384	71	the	the	DET
fnp-3528	384	72	lipids	lipid	NOUN
fnp-3528	384	73	,	,	PUNCT
fnp-3528	384	74	and	and	CCONJ
fnp-3528	384	75	hence	hence	ADV
fnp-3528	384	76	,	,	PUNCT
fnp-3528	384	77	are	be	AUX
fnp-3528	384	78	less	less	ADV
fnp-3528	384	79	suitable	suitable	ADJ
fnp-3528	384	80	to	to	PART
fnp-3528	384	81	track	track	VERB
fnp-3528	384	82	the	the	DET
fnp-3528	384	83	function	function	NOUN
fnp-3528	384	84	of	of	ADP
fnp-3528	384	85	abca	abca	NOUN
fnp-3528	384	86	transporters	transporter	NOUN
fnp-3528	384	87	in	in	ADP
fnp-3528	384	88	real	real	ADJ
fnp-3528	384	89	-	-	PUNCT
fnp-3528	384	90	time	time	NOUN
fnp-3528	384	91	and	and	CCONJ
fnp-3528	384	92	to	to	PART
fnp-3528	384	93	determine	determine	VERB
fnp-3528	384	94	kinetic	kinetic	ADJ
fnp-3528	384	95	aspects	aspect	NOUN
fnp-3528	384	96	of	of	ADP
fnp-3528	384	97	their	their	PRON
fnp-3528	384	98	cholesterol	cholesterol	NOUN
fnp-3528	384	99	and	and	CCONJ
fnp-3528	384	100	lipid	lipid	NOUN
fnp-3528	384	101	transport	transport	NOUN
fnp-3528	384	102	.	.	PUNCT
fnp-3528	385	1	in	in	ADP
fnp-3528	385	2	rare	rare	ADJ
fnp-3528	385	3	instances	instance	NOUN
fnp-3528	385	4	,	,	PUNCT
fnp-3528	385	5	the	the	DET
fnp-3528	385	6	extraction	extraction	NOUN
fnp-3528	385	7	of	of	ADP
fnp-3528	385	8	lipid	lipid	ADJ
fnp-3528	385	9	components	component	NOUN
fnp-3528	385	10	was	be	AUX
fnp-3528	385	11	accomplished	accomplish	VERB
fnp-3528	385	12	after	after	ADP
fnp-3528	385	13	incubation	incubation	NOUN
fnp-3528	385	14	with	with	ADP
fnp-3528	385	15	a	a	DET
fnp-3528	385	16	radioactive	radioactive	ADJ
fnp-3528	385	17	marker.246	marker.246	NOUN
fnp-3528	385	18	while	while	SCONJ
fnp-3528	385	19	this	this	PRON
fnp-3528	385	20	is	be	AUX
fnp-3528	385	21	a	a	DET
fnp-3528	385	22	valid	valid	ADJ
fnp-3528	385	23	methodology	methodology	NOUN
fnp-3528	385	24	to	to	PART
fnp-3528	385	25	accurately	accurately	ADV
fnp-3528	385	26	determine	determine	VERB
fnp-3528	385	27	lipid	lipid	NOUN
fnp-3528	385	28	components	component	NOUN
fnp-3528	385	29	within	within	ADP
fnp-3528	385	30	cells	cell	NOUN
fnp-3528	385	31	,	,	PUNCT
fnp-3528	385	32	it	it	PRON
fnp-3528	385	33	increases	increase	VERB
fnp-3528	385	34	workload	workload	NOUN
fnp-3528	385	35	and	and	CCONJ
fnp-3528	385	36	attracts	attract	VERB
fnp-3528	385	37	regulatory	regulatory	ADJ
fnp-3528	385	38	constraints	constraint	NOUN
fnp-3528	385	39	.	.	PUNCT
fnp-3528	386	1	gas	gas	NOUN
fnp-3528	386	2	-	-	PUNCT
fnp-3528	386	3	liquid	liquid	ADJ
fnp-3528	386	4	chromatography	chromatography	NOUN
fnp-3528	386	5	has	have	AUX
fnp-3528	386	6	also	also	ADV
fnp-3528	386	7	been	be	AUX
fnp-3528	386	8	used	use	VERB
fnp-3528	386	9	in	in	ADP
fnp-3528	386	10	some	some	DET
fnp-3528	386	11	reports.353,355	reports.353,355	ADJ
fnp-3528	386	12	an	an	DET
fnp-3528	386	13	extraction	extraction	NOUN
fnp-3528	386	14	-	-	PUNCT
fnp-3528	386	15	free	free	ADJ
fnp-3528	386	16	staining	staining	NOUN
fnp-3528	386	17	of	of	ADP
fnp-3528	386	18	cholesterol	cholesterol	NOUN
fnp-3528	386	19	inside	inside	ADP
fnp-3528	386	20	of	of	ADP
fnp-3528	386	21	cells	cell	NOUN
fnp-3528	386	22	was	be	AUX
fnp-3528	386	23	also	also	ADV
fnp-3528	386	24	demonstrated	demonstrate	VERB
fnp-3528	386	25	(	(	PUNCT
fnp-3528	386	26	filipin	filipin	NOUN
fnp-3528	386	27	iii251,331,333,341,358	iii251,331,333,341,358	PROPN
fnp-3528	386	28	or	or	CCONJ
fnp-3528	386	29	oil	oil	NOUN
fnp-3528	386	30	red	red	ADJ
fnp-3528	386	31	o	o	NOUN
fnp-3528	386	32	staining	stain	VERB
fnp-3528	386	33	330,332,364,366,369,375,388,389,392,393,399,402,410,417,421,425,448	330,332,364,366,369,375,388,389,392,393,399,402,410,417,421,425,448	PROPN
fnp-3528	386	34	)	)	PUNCT
fnp-3528	386	35	.	.	PUNCT
fnp-3528	387	1	however	however	ADV
fnp-3528	387	2	,	,	PUNCT
fnp-3528	387	3	these	these	DET
fnp-3528	387	4	systems	system	NOUN
fnp-3528	387	5	are	be	AUX
fnp-3528	387	6	not	not	PART
fnp-3528	387	7	suitable	suitable	ADJ
fnp-3528	387	8	to	to	PART
fnp-3528	387	9	track	track	VERB
fnp-3528	387	10	single	single	ADJ
fnp-3528	387	11	-	-	PUNCT
fnp-3528	387	12	cell	cell	NOUN
fnp-3528	387	13	abca	abca	NOUN
fnp-3528	387	14	-	-	PUNCT
fnp-3528	387	15	mediated	mediate	VERB
fnp-3528	387	16	cholesterol	cholesterol	NOUN
fnp-3528	387	17	or	or	CCONJ
fnp-3528	387	18	phospholipid	phospholipid	NOUN
fnp-3528	387	19	transport	transport	NOUN
fnp-3528	387	20	.	.	PUNCT
fnp-3528	388	1	quantification	quantification	NOUN
fnp-3528	388	2	of	of	ADP
fnp-3528	388	3	abca	abca	NOUN
fnp-3528	388	4	transporter	transporter	NOUN
fnp-3528	388	5	regulation	regulation	NOUN
fnp-3528	388	6	besides	besides	SCONJ
fnp-3528	388	7	qpcr	qpcr	ADV
fnp-3528	388	8	and	and	CCONJ
fnp-3528	388	9	western	western	ADJ
fnp-3528	388	10	blotting	blotting	NOUN
fnp-3528	388	11	,	,	PUNCT
fnp-3528	388	12	abca	abca	NOUN
fnp-3528	388	13	transporter	transporter	NOUN
fnp-3528	388	14	expression	expression	NOUN
fnp-3528	388	15	was	be	AUX
fnp-3528	388	16	reported	report	VERB
fnp-3528	388	17	in	in	ADP
fnp-3528	388	18	several	several	ADJ
fnp-3528	388	19	studies	study	NOUN
fnp-3528	388	20	using	use	VERB
fnp-3528	388	21	fluorimetric	fluorimetric	ADJ
fnp-3528	388	22	assays	assay	NOUN
fnp-3528	388	23	.	.	PUNCT
fnp-3528	389	1	this	this	PRON
fnp-3528	389	2	was	be	AUX
fnp-3528	389	3	accomplished	accomplish	VERB
fnp-3528	389	4	with	with	ADP
fnp-3528	389	5	either	either	CCONJ
fnp-3528	389	6	(	(	PUNCT
fnp-3528	389	7	i	i	NOUN
fnp-3528	389	8	)	)	PUNCT
fnp-3528	389	9	green	green	ADJ
fnp-3528	389	10	fluorescent	fluorescent	NOUN
fnp-3528	389	11	protein-(gfp)tagged	protein-(gfp)tagge	VERB
fnp-3528	389	12	/	/	SYM
fnp-3528	389	13	labelled	label	VERB
fnp-3528	389	14	abca	abca	PROPN
fnp-3528	389	15	transporters235,241,261,275,386,422,464,504	transporters235,241,261,275,386,422,464,504	PROPN
fnp-3528	389	16	or	or	CCONJ
fnp-3528	389	17	(	(	PUNCT
fnp-3528	389	18	ii	ii	NOUN
fnp-3528	389	19	)	)	PUNCT
fnp-3528	389	20	luciferase	luciferase	VERB
fnp-3528	389	21	promotor-(luc)-transfected271,309,319,352,367,379,381,405	promotor-(luc)-transfected271,309,319,352,367,379,381,405	PROPN
fnp-3528	389	22	,	,	PUNCT
fnp-3528	389	23	406,419,436,447	406,419,436,447	NUM
fnp-3528	389	24	abca	abca	NOUN
fnp-3528	389	25	transporter	transporter	NOUN
fnp-3528	389	26	cells	cell	NOUN
fnp-3528	389	27	in	in	ADP
fnp-3528	389	28	luciferase	luciferase	ADJ
fnp-3528	389	29	reporter	reporter	NOUN
fnp-3528	389	30	gene	gene	NOUN
fnp-3528	389	31	assays	assay	NOUN
fnp-3528	389	32	.	.	PUNCT
fnp-3528	390	1	in	in	ADP
fnp-3528	390	2	vivo	vivo	ADJ
fnp-3528	390	3	assessment	assessment	NOUN
fnp-3528	390	4	of	of	ADP
fnp-3528	390	5	clinical	clinical	ADJ
fnp-3528	390	6	candidates	candidate	NOUN
fnp-3528	390	7	in	in	ADP
fnp-3528	390	8	vivo	vivo	NOUN
fnp-3528	390	9	models	model	NOUN
fnp-3528	390	10	play	play	VERB
fnp-3528	390	11	a	a	DET
fnp-3528	390	12	key	key	ADJ
fnp-3528	390	13	role	role	NOUN
fnp-3528	390	14	in	in	ADP
fnp-3528	390	15	drug	drug	NOUN
fnp-3528	390	16	discovery	discovery	NOUN
fnp-3528	390	17	.	.	PUNCT
fnp-3528	391	1	although	although	SCONJ
fnp-3528	391	2	in	in	ADP
fnp-3528	391	3	vitro	vitro	X
fnp-3528	391	4	and	and	CCONJ
fnp-3528	391	5	cellular	cellular	ADJ
fnp-3528	391	6	models	model	NOUN
fnp-3528	391	7	are	be	AUX
fnp-3528	391	8	less	less	ADV
fnp-3528	391	9	expensive	expensive	ADJ
fnp-3528	391	10	and	and	CCONJ
fnp-3528	391	11	less	less	ADJ
fnp-3528	391	12	time	time	NOUN
fnp-3528	391	13	consuming	consume	VERB
fnp-3528	391	14	,	,	PUNCT
fnp-3528	391	15	in	in	ADP
fnp-3528	391	16	vivo	vivo	NOUN
fnp-3528	391	17	models	model	NOUN
fnp-3528	391	18	are	be	AUX
fnp-3528	391	19	needed	need	VERB
fnp-3528	391	20	to	to	PART
fnp-3528	391	21	test	test	VERB
fnp-3528	391	22	abca	abca	NOUN
fnp-3528	391	23	modulators	modulator	NOUN
fnp-3528	391	24	under	under	ADP
fnp-3528	391	25	physiological	physiological	ADJ
fnp-3528	391	26	conditions	condition	NOUN
fnp-3528	391	27	.	.	PUNCT
fnp-3528	392	1	safety	safety	NOUN
fnp-3528	392	2	,	,	PUNCT
fnp-3528	392	3	toxicity	toxicity	NOUN
fnp-3528	392	4	,	,	PUNCT
fnp-3528	392	5	and	and	CCONJ
fnp-3528	392	6	efficacy	efficacy	NOUN
fnp-3528	392	7	of	of	ADP
fnp-3528	392	8	a	a	DET
fnp-3528	392	9	drug	drug	NOUN
fnp-3528	392	10	candidate	candidate	NOUN
fnp-3528	392	11	must	must	AUX
fnp-3528	392	12	be	be	AUX
fnp-3528	392	13	tested	test	VERB
fnp-3528	392	14	in	in	ADP
fnp-3528	392	15	an	an	DET
fnp-3528	392	16	in	in	ADP
fnp-3528	392	17	vivo	vivo	NOUN
fnp-3528	392	18	model	model	NOUN
fnp-3528	392	19	as	as	ADP
fnp-3528	392	20	a	a	DET
fnp-3528	392	21	last	last	ADJ
fnp-3528	392	22	step	step	NOUN
fnp-3528	392	23	before	before	ADP
fnp-3528	392	24	transferring	transfer	VERB
fnp-3528	392	25	it	it	PRON
fnp-3528	392	26	to	to	ADP
fnp-3528	392	27	clinical	clinical	ADJ
fnp-3528	392	28	evaluation	evaluation	NOUN
fnp-3528	392	29	.	.	PUNCT
fnp-3528	393	1	however	however	ADV
fnp-3528	393	2	,	,	PUNCT
fnp-3528	393	3	these	these	DET
fnp-3528	393	4	models	model	NOUN
fnp-3528	393	5	also	also	ADV
fnp-3528	393	6	have	have	VERB
fnp-3528	393	7	disadvantages	disadvantage	NOUN
fnp-3528	393	8	.	.	PUNCT
fnp-3528	394	1	animal	animal	NOUN
fnp-3528	394	2	studies	study	NOUN
fnp-3528	394	3	are	be	AUX
fnp-3528	394	4	time	time	NOUN
fnp-3528	394	5	consuming	consume	VERB
fnp-3528	394	6	and	and	CCONJ
fnp-3528	394	7	require	require	VERB
fnp-3528	394	8	advanced	advanced	ADJ
fnp-3528	394	9	personnel	personnel	NOUN
fnp-3528	394	10	training	training	NOUN
fnp-3528	394	11	and	and	CCONJ
fnp-3528	394	12	resources	resource	NOUN
fnp-3528	394	13	for	for	ADP
fnp-3528	394	14	maintaining	maintain	VERB
fnp-3528	394	15	the	the	DET
fnp-3528	394	16	animals	animal	NOUN
fnp-3528	394	17	.	.	PUNCT
fnp-3528	395	1	in	in	ADP
fnp-3528	395	2	addition	addition	NOUN
fnp-3528	395	3	,	,	PUNCT
fnp-3528	395	4	although	although	SCONJ
fnp-3528	395	5	they	they	PRON
fnp-3528	395	6	are	be	AUX
fnp-3528	395	7	closer	close	ADJ
fnp-3528	395	8	to	to	ADP
fnp-3528	395	9	humans	human	NOUN
fnp-3528	395	10	than	than	ADP
fnp-3528	395	11	in	in	ADP
fnp-3528	395	12	vitro	vitro	X
fnp-3528	395	13	models	model	NOUN
fnp-3528	395	14	,	,	PUNCT
fnp-3528	395	15	there	there	PRON
fnp-3528	395	16	are	be	VERB
fnp-3528	395	17	considerable	considerable	ADJ
fnp-3528	395	18	physiological	physiological	ADJ
fnp-3528	395	19	differences	difference	NOUN
fnp-3528	395	20	between	between	ADP
fnp-3528	395	21	species	specie	NOUN
fnp-3528	395	22	with	with	ADP
fnp-3528	395	23	respect	respect	NOUN
fnp-3528	395	24	to	to	ADP
fnp-3528	395	25	drug	drug	NOUN
fnp-3528	395	26	absorption	absorption	NOUN
fnp-3528	395	27	,	,	PUNCT
fnp-3528	395	28	metabolism	metabolism	NOUN
fnp-3528	395	29	,	,	PUNCT
fnp-3528	395	30	and	and	CCONJ
fnp-3528	395	31	excretion	excretion	NOUN
fnp-3528	395	32	,	,	PUNCT
fnp-3528	395	33	which	which	PRON
fnp-3528	395	34	may	may	AUX
fnp-3528	395	35	impede	impede	VERB
fnp-3528	395	36	translatability	translatability	NOUN
fnp-3528	395	37	.	.	PUNCT
fnp-3528	396	1	furthermore	furthermore	ADV
fnp-3528	396	2	,	,	PUNCT
fnp-3528	396	3	the	the	DET
fnp-3528	396	4	use	use	NOUN
fnp-3528	396	5	of	of	ADP
fnp-3528	396	6	animals	animal	NOUN
fnp-3528	396	7	in	in	ADP
fnp-3528	396	8	research	research	NOUN
fnp-3528	396	9	has	have	VERB
fnp-3528	396	10	its	its	PRON
fnp-3528	396	11	ethical	ethical	ADJ
fnp-3528	396	12	concerns	concern	NOUN
fnp-3528	396	13	.	.	PUNCT
fnp-3528	397	1	thus	thus	ADV
fnp-3528	397	2	,	,	PUNCT
fnp-3528	397	3	in	in	ADP
fnp-3528	397	4	recent	recent	ADJ
fnp-3528	397	5	years	year	NOUN
fnp-3528	397	6	,	,	PUNCT
fnp-3528	397	7	research	research	NOUN
fnp-3528	397	8	has	have	AUX
fnp-3528	397	9	been	be	AUX
fnp-3528	397	10	directed	direct	VERB
fnp-3528	397	11	to	to	PART
fnp-3528	397	12	reduce	reduce	VERB
fnp-3528	397	13	animal	animal	NOUN
fnp-3528	397	14	use	use	NOUN
fnp-3528	397	15	and	and	CCONJ
fnp-3528	397	16	increase	increase	VERB
fnp-3528	397	17	animal	animal	NOUN
fnp-3528	397	18	welfare	welfare	NOUN
fnp-3528	397	19	.	.	PUNCT
fnp-3528	398	1	in	in	ADP
fnp-3528	398	2	vivo	vivo	NOUN
fnp-3528	398	3	models	model	NOUN
fnp-3528	398	4	have	have	AUX
fnp-3528	398	5	previously	previously	ADV
fnp-3528	398	6	been	be	AUX
fnp-3528	398	7	used	use	VERB
fnp-3528	398	8	to	to	PART
fnp-3528	398	9	study	study	VERB
fnp-3528	398	10	the	the	DET
fnp-3528	398	11	role	role	NOUN
fnp-3528	398	12	of	of	ADP
fnp-3528	398	13	abca	abca	NOUN
fnp-3528	398	14	transporters	transporter	NOUN
fnp-3528	398	15	in	in	ADP
fnp-3528	398	16	physiology	physiology	NOUN
fnp-3528	398	17	and	and	CCONJ
fnp-3528	398	18	disease	disease	NOUN
fnp-3528	398	19	as	as	SCONJ
fnp-3528	398	20	described	describe	VERB
fnp-3528	398	21	above	above	ADV
fnp-3528	398	22	.	.	PUNCT
fnp-3528	399	1	thus	thus	ADV
fnp-3528	399	2	,	,	PUNCT
fnp-3528	399	3	there	there	PRON
fnp-3528	399	4	are	be	VERB
fnp-3528	399	5	already	already	ADV
fnp-3528	399	6	available	available	ADJ
fnp-3528	399	7	animal	animal	NOUN
fnp-3528	399	8	models	model	NOUN
fnp-3528	399	9	for	for	ADP
fnp-3528	399	10	testing	testing	NOUN
fnp-3528	399	11	of	of	ADP
fnp-3528	399	12	abca	abca	NOUN
fnp-3528	399	13	modulators	modulator	NOUN
fnp-3528	399	14	for	for	ADP
fnp-3528	399	15	the	the	DET
fnp-3528	399	16	most	most	ADV
fnp-3528	399	17	prominent	prominent	ADJ
fnp-3528	399	18	subtypes	subtype	NOUN
fnp-3528	399	19	(	(	PUNCT
fnp-3528	399	20	table	table	NOUN
fnp-3528	399	21	 	 	SPACE
fnp-3528	399	22	6	6	NUM
fnp-3528	399	23	)	)	PUNCT
fnp-3528	399	24	.	.	PUNCT
fnp-3528	400	1	as	as	SCONJ
fnp-3528	400	2	stated	state	VERB
fnp-3528	400	3	above	above	ADV
fnp-3528	400	4	,	,	PUNCT
fnp-3528	400	5	these	these	DET
fnp-3528	400	6	models	model	NOUN
fnp-3528	400	7	represent	represent	VERB
fnp-3528	400	8	the	the	DET
fnp-3528	400	9	last	last	ADJ
fnp-3528	400	10	step	step	NOUN
fnp-3528	400	11	before	before	ADP
fnp-3528	400	12	clinical	clinical	ADJ
fnp-3528	400	13	evaluation	evaluation	NOUN
fnp-3528	400	14	of	of	ADP
fnp-3528	400	15	potential	potential	ADJ
fnp-3528	400	16	small	small	ADJ
fnp-3528	400	17	-	-	PUNCT
fnp-3528	400	18	molecule	molecule	NOUN
fnp-3528	400	19	therapeutics	therapeutic	NOUN
fnp-3528	400	20	in	in	ADP
fnp-3528	400	21	humans	human	NOUN
fnp-3528	400	22	.	.	PUNCT
fnp-3528	401	1	thus	thus	ADV
fnp-3528	401	2	,	,	PUNCT
fnp-3528	401	3	after	after	ADP
fnp-3528	401	4	in	in	ADP
fnp-3528	401	5	silico	silico	NOUN
fnp-3528	401	6	identification	identification	NOUN
fnp-3528	401	7	and	and	CCONJ
fnp-3528	401	8	in	in	ADP
fnp-3528	401	9	vitro	vitro	X
fnp-3528	401	10	assessment	assessment	NOUN
fnp-3528	401	11	,	,	PUNCT
fnp-3528	401	12	these	these	PRON
fnp-3528	401	13	in	in	ADP
fnp-3528	401	14	vivo	vivo	NOUN
fnp-3528	401	15	models	model	NOUN
fnp-3528	401	16	are	be	AUX
fnp-3528	401	17	the	the	DET
fnp-3528	401	18	third	third	ADJ
fnp-3528	401	19	column	column	NOUN
fnp-3528	401	20	in	in	ADP
fnp-3528	401	21	the	the	DET
fnp-3528	401	22	development	development	NOUN
fnp-3528	401	23	of	of	ADP
fnp-3528	401	24	novel	novel	ADJ
fnp-3528	401	25	abca	abca	NOUN
fnp-3528	401	26	transporter	transporter	NOUN
fnp-3528	401	27	diagnostics	diagnostic	NOUN
fnp-3528	401	28	and	and	CCONJ
fnp-3528	401	29	therapeutics	therapeutic	NOUN
fnp-3528	401	30	.	.	PUNCT
fnp-3528	402	1	in	in	ADP
fnp-3528	402	2	the	the	DET
fnp-3528	402	3	following	following	ADJ
fnp-3528	402	4	section	section	NOUN
fnp-3528	402	5	,	,	PUNCT
fnp-3528	402	6	different	different	ADJ
fnp-3528	402	7	in	in	ADP
fnp-3528	402	8	vivo	vivo	NOUN
fnp-3528	402	9	models	model	NOUN
fnp-3528	402	10	will	will	AUX
fnp-3528	402	11	be	be	AUX
fnp-3528	402	12	described	describe	VERB
fnp-3528	402	13	in	in	ADP
fnp-3528	402	14	more	more	ADJ
fnp-3528	402	15	detail	detail	NOUN
fnp-3528	402	16	.	.	PUNCT
fnp-3528	403	1	table	table	NOUN
fnp-3528	403	2	6	6	NUM
fnp-3528	403	3	.	.	PUNCT
fnp-3528	403	4	animal	animal	NOUN
fnp-3528	403	5	models	model	NOUN
fnp-3528	403	6	to	to	PART
fnp-3528	403	7	study	study	VERB
fnp-3528	403	8	the	the	DET
fnp-3528	403	9	functional	functional	ADJ
fnp-3528	403	10	and	and	CCONJ
fnp-3528	403	11	pathological	pathological	ADJ
fnp-3528	403	12	role	role	NOUN
fnp-3528	403	13	of	of	ADP
fnp-3528	403	14	abca	abca	PROPN
fnp-3528	403	15	transporters	transporter	NOUN
fnp-3528	403	16	.	.	PUNCT
fnp-3528	404	1	transporter	transporter	NOUN
fnp-3528	404	2	type	type	NOUN
fnp-3528	404	3	species	specie	NOUN
fnp-3528	404	4	phenotype	phenotype	NOUN
fnp-3528	404	5	references	reference	NOUN
fnp-3528	404	6	abca1	abca1	NOUN
fnp-3528	404	7	knock	knock	VERB
fnp-3528	404	8	-	-	PUNCT
fnp-3528	404	9	out	out	ADP
fnp-3528	404	10	mouse	mouse	NOUN
fnp-3528	404	11	reduced	reduce	VERB
fnp-3528	404	12	cholesterol	cholesterol	NOUN
fnp-3528	404	13	and	and	CCONJ
fnp-3528	404	14	plasma	plasma	NOUN
fnp-3528	404	15	phospholipid	phospholipid	NOUN
fnp-3528	404	16	levels	level	NOUN
fnp-3528	404	17	decreased	decrease	VERB
fnp-3528	404	18	brain	brain	NOUN
fnp-3528	404	19	apoe	apoe	PROPN
fnp-3528	404	20	levels	level	NOUN
fnp-3528	404	21	poorly	poorly	ADV
fnp-3528	404	22	lipidated	lipidate	VERB
fnp-3528	404	23	apoe	apoe	ADV
fnp-3528	404	24	161	161	NUM
fnp-3528	404	25	-	-	SYM
fnp-3528	404	26	163	163	NUM
fnp-3528	404	27	https://www.jax.org/strain/003897	https://www.jax.org/strain/003897	NOUN
fnp-3528	404	28	overexpression	overexpression	NOUN
fnp-3528	404	29	mouse	mouse	NOUN
fnp-3528	404	30	increased	increase	VERB
fnp-3528	404	31	lipidation	lipidation	NOUN
fnp-3528	404	32	of	of	ADP
fnp-3528	404	33	apoe	apoe	ADJ
fnp-3528	404	34	127	127	NUM
fnp-3528	404	35	abca2	abca2	NOUN
fnp-3528	404	36	knock	knock	NOUN
fnp-3528	404	37	-	-	PUNCT
fnp-3528	404	38	out	out	ADP
fnp-3528	404	39	mouse	mouse	NOUN
fnp-3528	404	40	reduced	reduce	VERB
fnp-3528	404	41	body	body	NOUN
fnp-3528	404	42	weight	weight	NOUN
fnp-3528	404	43	,	,	PUNCT
fnp-3528	404	44	limb	limb	NOUN
fnp-3528	404	45	tremor	tremor	NOUN
fnp-3528	404	46	,	,	PUNCT
fnp-3528	404	47	reduced	reduce	VERB
fnp-3528	404	48	sphingomyelin	sphingomyelin	NOUN
fnp-3528	404	49	https://www.jax.org/strain/033139	https://www.jax.org/strain/033139	ADP
fnp-3528	404	50	54,527	54,527	NUM
fnp-3528	404	51	abca3	abca3	NOUN
fnp-3528	404	52	knock	knock	VERB
fnp-3528	404	53	-	-	PUNCT
fnp-3528	404	54	out	out	ADP
fnp-3528	404	55	mouse	mouse	NOUN
fnp-3528	404	56	knocked	knock	VERB
fnp-3528	404	57	-	-	PUNCT
fnp-3528	404	58	out	out	ADP
fnp-3528	404	59	pups	pup	NOUN
fnp-3528	404	60	die	die	VERB
fnp-3528	404	61	within	within	ADP
fnp-3528	404	62	1h	1h	NUM
fnp-3528	404	63	after	after	ADP
fnp-3528	404	64	birth	birth	NOUN
fnp-3528	404	65	186,528,529	186,528,529	NUM
fnp-3528	404	66	missense	missense	NOUN
fnp-3528	404	67	mutation	mutation	NOUN
fnp-3528	404	68	mouse	mouse	NOUN
fnp-3528	404	69	early	early	ADJ
fnp-3528	404	70	macrophage	macrophage	ADJ
fnp-3528	404	71	predominant	predominant	NOUN
fnp-3528	404	72	alveolitis	alveolitis	PROPN
fnp-3528	404	73	which	which	PRON
fnp-3528	404	74	peaked	peak	VERB
fnp-3528	404	75	at	at	ADP
fnp-3528	404	76	8	8	NUM
fnp-3528	404	77	weeks	week	NOUN
fnp-3528	404	78	of	of	ADP
fnp-3528	404	79	age	age	NOUN
fnp-3528	404	80	530	530	NUM
fnp-3528	404	81	abca4	abca4	VERB
fnp-3528	404	82	knock	knock	VERB
fnp-3528	404	83	-	-	PUNCT
fnp-3528	404	84	out	out	ADP
fnp-3528	404	85	mouse	mouse	NOUN
fnp-3528	404	86	abnormal	abnormal	ADJ
fnp-3528	404	87	phospholipid	phospholipid	NOUN
fnp-3528	404	88	composition	composition	NOUN
fnp-3528	404	89	,	,	PUNCT
fnp-3528	404	90	delayed	delay	VERB
fnp-3528	404	91	dark	dark	ADJ
fnp-3528	404	92	adaptation	adaptation	NOUN
fnp-3528	404	93	531,532	531,532	NUM
fnp-3528	404	94	abca5	abca5	NOUN
fnp-3528	404	95	knock	knock	VERB
fnp-3528	404	96	-	-	PUNCT
fnp-3528	404	97	out	out	ADP
fnp-3528	404	98	mouse	mouse	NOUN
fnp-3528	404	99	exophthalmos	exophthalmos	NOUN
fnp-3528	404	100	and	and	CCONJ
fnp-3528	404	101	collapsed	collapse	VERB
fnp-3528	404	102	thyroid	thyroid	NOUN
fnp-3528	404	103	gland	gland	NOUN
fnp-3528	404	104	,	,	PUNCT
fnp-3528	404	105	early	early	ADJ
fnp-3528	404	106	death	death	NOUN
fnp-3528	404	107	due	due	ADP
fnp-3528	404	108	to	to	ADP
fnp-3528	404	109	cardiac	cardiac	ADJ
fnp-3528	404	110	insufficiency	insufficiency	NOUN
fnp-3528	404	111	123,131	123,131	NUM
fnp-3528	404	112	abca7	abca7	NOUN
fnp-3528	404	113	knock	knock	VERB
fnp-3528	404	114	-	-	PUNCT
fnp-3528	404	115	out	out	ADP
fnp-3528	404	116	humanized	humanize	VERB
fnp-3528	404	117	mouse	mouse	NOUN
fnp-3528	404	118	mouse	mouse	NOUN
fnp-3528	404	119	reduced	reduce	VERB
fnp-3528	404	120	microglia	microglia	ADJ
fnp-3528	404	121	response	response	NOUN
fnp-3528	404	122	altered	alter	VERB
fnp-3528	404	123	phagocytosis	phagocytosis	NOUN
fnp-3528	404	124	increased	increase	VERB
fnp-3528	404	125	β	β	NOUN
fnp-3528	404	126	-	-	NOUN
fnp-3528	404	127	secretase	secretase	NOUN
fnp-3528	404	128	under	under	ADP
fnp-3528	404	129	characterization	characterization	NOUN
fnp-3528	404	130	,	,	PUNCT
fnp-3528	404	131	increase	increase	VERB
fnp-3528	404	132	aβ	aβ	DET
fnp-3528	404	133	load	load	NOUN
fnp-3528	404	134	124	124	NUM
fnp-3528	404	135	abca7tm1.1(abca7)pahnk	abca7tm1.1(abca7)pahnk	PROPN
fnp-3528	404	136	mgi:6258226	mgi:6258226	PROPN
fnp-3528	404	137	abca8	abca8	PROPN
fnp-3528	404	138	knock	knock	VERB
fnp-3528	404	139	-	-	PUNCT
fnp-3528	404	140	out	out	ADP
fnp-3528	404	141	mouse	mouse	NOUN
fnp-3528	404	142	reduced	reduce	VERB
fnp-3528	404	143	plasma	plasma	NOUN
fnp-3528	404	144	hdl	hdl	PROPN
fnp-3528	404	145	533	533	NUM
fnp-3528	404	146	adenoviral	adenoviral	ADJ
fnp-3528	404	147	overexpression	overexpression	NOUN
fnp-3528	404	148	mouse	mouse	NOUN
fnp-3528	404	149	increased	increase	VERB
fnp-3528	404	150	plasma	plasma	NOUN
fnp-3528	404	151	hdl	hdl	NOUN
fnp-3528	404	152	and	and	CCONJ
fnp-3528	404	153	cholesterol	cholesterol	NOUN
fnp-3528	404	154	533	533	NUM
fnp-3528	404	155	abca12	abca12	NOUN
fnp-3528	404	156	not	not	PART
fnp-3528	404	157	described	describe	VERB
fnp-3528	404	158	https://www.jax.org/strain/033630	https://www.jax.org/strain/033630	NOUN
fnp-3528	404	159	abca13	abca13	NOUN
fnp-3528	404	160	knock	knock	VERB
fnp-3528	404	161	-	-	PUNCT
fnp-3528	404	162	out	out	ADP
fnp-3528	404	163	mouse	mouse	NOUN
fnp-3528	404	164	monkey	monkey	NOUN
fnp-3528	404	165	deficits	deficit	NOUN
fnp-3528	404	166	of	of	ADP
fnp-3528	404	167	prepulse	prepulse	NOUN
fnp-3528	404	168	inhibition	inhibition	NOUN
fnp-3528	404	169	impaired	impaired	ADJ
fnp-3528	404	170	neuronal	neuronal	ADJ
fnp-3528	404	171	formation	formation	NOUN
fnp-3528	404	172	,	,	PUNCT
fnp-3528	404	173	neurotransmitter	neurotransmitter	NOUN
fnp-3528	404	174	alterations	alteration	NOUN
fnp-3528	404	175	48	48	NUM
fnp-3528	404	176	534	534	NUM
fnp-3528	404	177	knock	knock	VERB
fnp-3528	404	178	-	-	PUNCT
fnp-3528	404	179	out	out	ADP
fnp-3528	404	180	mouse	mouse	NOUN
fnp-3528	404	181	models	model	NOUN
fnp-3528	404	182	a	a	DET
fnp-3528	404	183	genetic	genetic	ADJ
fnp-3528	404	184	knock	knock	NOUN
fnp-3528	404	185	-	-	PUNCT
fnp-3528	404	186	out	out	ADP
fnp-3528	404	187	mouse	mouse	NOUN
fnp-3528	404	188	model	model	NOUN
fnp-3528	404	189	is	be	AUX
fnp-3528	404	190	an	an	DET
fnp-3528	404	191	animal	animal	NOUN
fnp-3528	404	192	model	model	NOUN
fnp-3528	404	193	in	in	ADP
fnp-3528	404	194	which	which	PRON
fnp-3528	404	195	one	one	NUM
fnp-3528	404	196	or	or	CCONJ
fnp-3528	404	197	more	more	ADJ
fnp-3528	404	198	genes	gene	NOUN
fnp-3528	404	199	of	of	ADP
fnp-3528	404	200	interest	interest	NOUN
fnp-3528	404	201	have	have	AUX
fnp-3528	404	202	been	be	AUX
fnp-3528	404	203	deactivated	deactivate	VERB
fnp-3528	404	204	or	or	CCONJ
fnp-3528	404	205	removed	remove	VERB
fnp-3528	404	206	by	by	ADP
fnp-3528	404	207	means	mean	NOUN
fnp-3528	404	208	of	of	ADP
fnp-3528	404	209	gene	gene	NOUN
fnp-3528	404	210	targeting	target	VERB
fnp-3528	404	211	.	.	PUNCT
fnp-3528	405	1	knock	knock	VERB
fnp-3528	405	2	-	-	PUNCT
fnp-3528	405	3	out	out	ADP
fnp-3528	405	4	animals	animal	NOUN
fnp-3528	405	5	allow	allow	VERB
fnp-3528	405	6	for	for	ADP
fnp-3528	405	7	direct	direct	ADJ
fnp-3528	405	8	investigation	investigation	NOUN
fnp-3528	405	9	of	of	ADP
fnp-3528	405	10	the	the	DET
fnp-3528	405	11	effect	effect	NOUN
fnp-3528	405	12	of	of	ADP
fnp-3528	405	13	a	a	DET
fnp-3528	405	14	specific	specific	ADJ
fnp-3528	405	15	gene	gene	NOUN
fnp-3528	405	16	in	in	ADP
fnp-3528	405	17	an	an	DET
fnp-3528	405	18	organism	organism	NOUN
fnp-3528	405	19	,	,	PUNCT
fnp-3528	405	20	as	as	SCONJ
fnp-3528	405	21	the	the	DET
fnp-3528	405	22	loss	loss	NOUN
fnp-3528	405	23	of	of	ADP
fnp-3528	405	24	gene	gene	NOUN
fnp-3528	405	25	activity	activity	NOUN
fnp-3528	405	26	often	often	ADV
fnp-3528	405	27	causes	cause	VERB
fnp-3528	405	28	phenotypic	phenotypic	ADJ
fnp-3528	405	29	changes	change	NOUN
fnp-3528	405	30	uncovering	uncover	VERB
fnp-3528	405	31	the	the	DET
fnp-3528	405	32	function	function	NOUN
fnp-3528	405	33	and	and	CCONJ
fnp-3528	405	34	biological	biological	ADJ
fnp-3528	405	35	mechanism	mechanism	NOUN
fnp-3528	405	36	of	of	ADP
fnp-3528	405	37	the	the	DET
fnp-3528	405	38	targeted	target	VERB
fnp-3528	405	39	gene.535	gene.535	NOUN
fnp-3528	405	40	knock	knock	NOUN
fnp-3528	405	41	-	-	PUNCT
fnp-3528	405	42	out	out	ADP
fnp-3528	405	43	mice	mouse	NOUN
fnp-3528	405	44	have	have	AUX
fnp-3528	405	45	become	become	VERB
fnp-3528	405	46	one	one	NUM
fnp-3528	405	47	of	of	ADP
fnp-3528	405	48	the	the	DET
fnp-3528	405	49	most	most	ADV
fnp-3528	405	50	useful	useful	ADJ
fnp-3528	405	51	scientific	scientific	ADJ
fnp-3528	405	52	tools	tool	NOUN
fnp-3528	405	53	to	to	PART
fnp-3528	405	54	analyze	analyze	VERB
fnp-3528	405	55	the	the	DET
fnp-3528	405	56	human	human	ADJ
fnp-3528	405	57	genome	genome	NOUN
fnp-3528	405	58	and	and	CCONJ
fnp-3528	405	59	its	its	PRON
fnp-3528	405	60	potential	potential	ADJ
fnp-3528	405	61	roles	role	NOUN
fnp-3528	405	62	in	in	ADP
fnp-3528	405	63	many	many	ADJ
fnp-3528	405	64	diseases.535	diseases.535	NOUN
fnp-3528	405	65	thus	thus	ADV
fnp-3528	405	66	,	,	PUNCT
fnp-3528	405	67	knock	knock	VERB
fnp-3528	405	68	-	-	PUNCT
fnp-3528	405	69	out	out	ADP
fnp-3528	405	70	animals	animal	NOUN
fnp-3528	405	71	are	be	AUX
fnp-3528	405	72	currently	currently	ADV
fnp-3528	405	73	essential	essential	ADJ
fnp-3528	405	74	experimental	experimental	ADJ
fnp-3528	405	75	tools	tool	NOUN
fnp-3528	405	76	for	for	ADP
fnp-3528	405	77	the	the	DET
fnp-3528	405	78	investigation	investigation	NOUN
fnp-3528	405	79	of	of	ADP
fnp-3528	405	80	genetic	genetic	ADJ
fnp-3528	405	81	disorders	disorder	NOUN
fnp-3528	405	82	and	and	CCONJ
fnp-3528	405	83	the	the	DET
fnp-3528	405	84	evaluation	evaluation	NOUN
fnp-3528	405	85	of	of	ADP
fnp-3528	405	86	novel	novel	ADJ
fnp-3528	405	87	drugs.536	drugs.536	NOUN
fnp-3528	405	88	furthermore	furthermore	ADV
fnp-3528	405	89	,	,	PUNCT
fnp-3528	405	90	the	the	DET
fnp-3528	405	91	current	current	ADJ
fnp-3528	405	92	knowledge	knowledge	NOUN
fnp-3528	405	93	on	on	ADP
fnp-3528	405	94	genome	genome	NOUN
fnp-3528	405	95	editing	editing	NOUN
fnp-3528	405	96	using	use	VERB
fnp-3528	405	97	the	the	DET
fnp-3528	405	98	crispr	crispr	ADJ
fnp-3528	405	99	/	/	SYM
fnp-3528	405	100	cas9	cas9	NOUN
fnp-3528	405	101	system	system	NOUN
fnp-3528	405	102	makes	make	VERB
fnp-3528	405	103	generation	generation	NOUN
fnp-3528	405	104	of	of	ADP
fnp-3528	405	105	knock	knock	NOUN
fnp-3528	405	106	-	-	PUNCT
fnp-3528	405	107	out	out	ADP
fnp-3528	405	108	lines	line	NOUN
fnp-3528	405	109	considerably	considerably	ADV
fnp-3528	405	110	faster	fast	ADV
fnp-3528	405	111	than	than	ADP
fnp-3528	405	112	with	with	ADP
fnp-3528	405	113	the	the	DET
fnp-3528	405	114	use	use	NOUN
fnp-3528	405	115	of	of	ADP
fnp-3528	405	116	embryonic	embryonic	ADJ
fnp-3528	405	117	stem	stem	NOUN
fnp-3528	405	118	cells	cell	NOUN
fnp-3528	405	119	.	.	PUNCT
fnp-3528	406	1	to	to	ADP
fnp-3528	406	2	no	no	DET
fnp-3528	406	3	surprise	surprise	NOUN
fnp-3528	406	4	,	,	PUNCT
fnp-3528	406	5	this	this	DET
fnp-3528	406	6	method	method	NOUN
fnp-3528	406	7	has	have	AUX
fnp-3528	406	8	quickly	quickly	ADV
fnp-3528	406	9	become	become	VERB
fnp-3528	406	10	the	the	DET
fnp-3528	406	11	most	most	ADV
fnp-3528	406	12	powerful	powerful	ADJ
fnp-3528	406	13	tool	tool	NOUN
fnp-3528	406	14	for	for	ADP
fnp-3528	406	15	generating	generate	VERB
fnp-3528	406	16	genetic	genetic	ADJ
fnp-3528	406	17	models.537	models.537	NOUN
fnp-3528	406	18	knock	knock	VERB
fnp-3528	406	19	-	-	PUNCT
fnp-3528	406	20	out	out	ADP
fnp-3528	406	21	animal	animal	NOUN
fnp-3528	406	22	models	model	NOUN
fnp-3528	406	23	are	be	AUX
fnp-3528	406	24	designed	design	VERB
fnp-3528	406	25	with	with	ADP
fnp-3528	406	26	two	two	NUM
fnp-3528	406	27	variables	variable	NOUN
fnp-3528	406	28	in	in	ADP
fnp-3528	406	29	mind	mind	NOUN
fnp-3528	406	30	:	:	PUNCT
fnp-3528	406	31	(	(	PUNCT
fnp-3528	406	32	i	i	NOUN
fnp-3528	406	33	)	)	PUNCT
fnp-3528	406	34	where	where	SCONJ
fnp-3528	406	35	and	and	CCONJ
fnp-3528	406	36	(	(	PUNCT
fnp-3528	406	37	ii	ii	NOUN
fnp-3528	406	38	)	)	PUNCT
fnp-3528	406	39	when	when	SCONJ
fnp-3528	406	40	is	be	AUX
fnp-3528	406	41	the	the	DET
fnp-3528	406	42	gene	gene	NOUN
fnp-3528	406	43	of	of	ADP
fnp-3528	406	44	interest	interest	NOUN
fnp-3528	406	45	deactivated	deactivate	VERB
fnp-3528	406	46	.	.	PUNCT
fnp-3528	407	1	the	the	DET
fnp-3528	407	2	simplest	simple	ADJ
fnp-3528	407	3	and	and	CCONJ
fnp-3528	407	4	most	most	ADV
fnp-3528	407	5	common	common	ADJ
fnp-3528	407	6	approach	approach	NOUN
fnp-3528	407	7	is	be	AUX
fnp-3528	407	8	a	a	DET
fnp-3528	407	9	constitutive	constitutive	ADJ
fnp-3528	407	10	,	,	PUNCT
fnp-3528	407	11	ubiquitous	ubiquitous	ADJ
fnp-3528	407	12	knock	knock	NOUN
fnp-3528	407	13	-	-	PUNCT
fnp-3528	407	14	out	out	NOUN
fnp-3528	407	15	,	,	PUNCT
fnp-3528	407	16	i.e.	i.e.	X
fnp-3528	407	17	,	,	PUNCT
fnp-3528	407	18	the	the	DET
fnp-3528	407	19	product	product	NOUN
fnp-3528	407	20	protein	protein	NOUN
fnp-3528	407	21	is	be	AUX
fnp-3528	407	22	absent	absent	ADJ
fnp-3528	407	23	permanently	permanently	ADV
fnp-3528	407	24	in	in	ADP
fnp-3528	407	25	all	all	DET
fnp-3528	407	26	cells	cell	NOUN
fnp-3528	407	27	of	of	ADP
fnp-3528	407	28	an	an	DET
fnp-3528	407	29	organism	organism	NOUN
fnp-3528	407	30	.	.	PUNCT
fnp-3528	408	1	to	to	PART
fnp-3528	408	2	overcome	overcome	VERB
fnp-3528	408	3	limitations	limitation	NOUN
fnp-3528	408	4	of	of	ADP
fnp-3528	408	5	this	this	DET
fnp-3528	408	6	broad	broad	ADJ
fnp-3528	408	7	approach	approach	NOUN
fnp-3528	408	8	,	,	PUNCT
fnp-3528	408	9	more	more	ADJ
fnp-3528	408	10	refined	refined	ADJ
fnp-3528	408	11	models	model	NOUN
fnp-3528	408	12	have	have	AUX
fnp-3528	408	13	been	be	AUX
fnp-3528	408	14	developed	develop	VERB
fnp-3528	408	15	.	.	PUNCT
fnp-3528	409	1	these	these	DET
fnp-3528	409	2	conditional	conditional	ADJ
fnp-3528	409	3	models	model	NOUN
fnp-3528	409	4	use	use	VERB
fnp-3528	409	5	cre	cre	PROPN
fnp-3528	409	6	-	-	PUNCT
fnp-3528	409	7	lox	lox	NOUN
fnp-3528	409	8	recombination	recombination	NOUN
fnp-3528	409	9	to	to	PART
fnp-3528	409	10	target	target	VERB
fnp-3528	409	11	a	a	DET
fnp-3528	409	12	gene	gene	NOUN
fnp-3528	409	13	either	either	CCONJ
fnp-3528	409	14	in	in	ADP
fnp-3528	409	15	specific	specific	ADJ
fnp-3528	409	16	cell	cell	NOUN
fnp-3528	409	17	populations	population	NOUN
fnp-3528	409	18	,	,	PUNCT
fnp-3528	409	19	at	at	ADP
fnp-3528	409	20	specific	specific	ADJ
fnp-3528	409	21	time	time	NOUN
fnp-3528	409	22	points	point	NOUN
fnp-3528	409	23	,	,	PUNCT
fnp-3528	409	24	or	or	CCONJ
fnp-3528	409	25	a	a	DET
fnp-3528	409	26	combination	combination	NOUN
fnp-3528	409	27	of	of	ADP
fnp-3528	409	28	both	both	PRON
fnp-3528	409	29	.	.	PUNCT
fnp-3528	410	1	here	here	ADV
fnp-3528	410	2	,	,	PUNCT
fnp-3528	410	3	the	the	DET
fnp-3528	410	4	target	target	NOUN
fnp-3528	410	5	gene	gene	NOUN
fnp-3528	410	6	is	be	AUX
fnp-3528	410	7	modified	modify	VERB
fnp-3528	410	8	by	by	ADP
fnp-3528	410	9	inserting	insert	VERB
fnp-3528	410	10	two	two	NUM
fnp-3528	410	11	loxp	loxp	ADJ
fnp-3528	410	12	sites	site	NOUN
fnp-3528	410	13	.	.	PUNCT
fnp-3528	411	1	the	the	DET
fnp-3528	411	2	flanked	flank	VERB
fnp-3528	411	3	gene	gene	NOUN
fnp-3528	411	4	segment	segment	NOUN
fnp-3528	411	5	can	can	AUX
fnp-3528	411	6	then	then	ADV
fnp-3528	411	7	be	be	AUX
fnp-3528	411	8	excised	excise	VERB
fnp-3528	411	9	by	by	ADP
fnp-3528	411	10	the	the	DET
fnp-3528	411	11	cre	cre	PROPN
fnp-3528	411	12	recombinase	recombinase	PROPN
fnp-3528	411	13	.	.	PUNCT
fnp-3528	411	14	cre	cre	PROPN
fnp-3528	411	15	activity	activity	NOUN
fnp-3528	411	16	,	,	PUNCT
fnp-3528	411	17	i.e.	i.e.	X
fnp-3528	411	18	,	,	PUNCT
fnp-3528	411	19	gene	gene	NOUN
fnp-3528	411	20	knock	knock	NOUN
fnp-3528	411	21	-	-	PUNCT
fnp-3528	411	22	out	out	NOUN
fnp-3528	411	23	,	,	PUNCT
fnp-3528	411	24	can	can	AUX
fnp-3528	411	25	be	be	AUX
fnp-3528	411	26	limited	limit	VERB
fnp-3528	411	27	to	to	ADP
fnp-3528	411	28	certain	certain	ADJ
fnp-3528	411	29	cell	cell	NOUN
fnp-3528	411	30	populations	population	NOUN
fnp-3528	411	31	by	by	ADP
fnp-3528	411	32	appropriate	appropriate	ADJ
fnp-3528	411	33	promotor	promotor	NOUN
fnp-3528	411	34	choice	choice	NOUN
fnp-3528	411	35	and/or	and/or	CCONJ
fnp-3528	411	36	linked	link	VERB
fnp-3528	411	37	to	to	ADP
fnp-3528	411	38	a	a	DET
fnp-3528	411	39	tamoxifen	tamoxifen	NOUN
fnp-3528	411	40	-	-	PUNCT
fnp-3528	411	41	responsive	responsive	ADJ
fnp-3528	411	42	element	element	NOUN
fnp-3528	411	43	to	to	PART
fnp-3528	411	44	control	control	VERB
fnp-3528	411	45	the	the	DET
fnp-3528	411	46	exact	exact	ADJ
fnp-3528	411	47	time	time	NOUN
fnp-3528	411	48	point	point	NOUN
fnp-3528	411	49	at	at	ADP
fnp-3528	411	50	which	which	PRON
fnp-3528	411	51	the	the	DET
fnp-3528	411	52	knock	knock	NOUN
fnp-3528	411	53	-	-	PUNCT
fnp-3528	411	54	out	out	NOUN
fnp-3528	411	55	is	be	AUX
fnp-3528	411	56	induced	induce	VERB
fnp-3528	411	57	.	.	PUNCT
fnp-3528	412	1	until	until	ADP
fnp-3528	412	2	now	now	ADV
fnp-3528	412	3	,	,	PUNCT
fnp-3528	412	4	several	several	ADJ
fnp-3528	412	5	abca	abca	NOUN
fnp-3528	412	6	animal	animal	NOUN
fnp-3528	412	7	knock	knock	NOUN
fnp-3528	412	8	-	-	PUNCT
fnp-3528	412	9	out	out	ADP
fnp-3528	412	10	models	model	NOUN
fnp-3528	412	11	have	have	AUX
fnp-3528	412	12	been	be	AUX
fnp-3528	412	13	described	describe	VERB
fnp-3528	412	14	,	,	PUNCT
fnp-3528	412	15	which	which	PRON
fnp-3528	412	16	are	be	AUX
fnp-3528	412	17	summarized	summarize	VERB
fnp-3528	412	18	in	in	ADP
fnp-3528	412	19	table	table	NOUN
fnp-3528	412	20	 	 	SPACE
fnp-3528	412	21	6	6	NUM
fnp-3528	412	22	.	.	PUNCT
fnp-3528	413	1	these	these	DET
fnp-3528	413	2	models	model	NOUN
fnp-3528	413	3	are	be	AUX
fnp-3528	413	4	mainly	mainly	ADV
fnp-3528	413	5	mouse	mouse	NOUN
fnp-3528	413	6	lines	line	NOUN
fnp-3528	413	7	,	,	PUNCT
fnp-3528	413	8	except	except	SCONJ
fnp-3528	413	9	for	for	ADP
fnp-3528	413	10	abca13	abca13	NOUN
fnp-3528	413	11	(	(	PUNCT
fnp-3528	413	12	monkey).534	monkey).534	VERB
fnp-3528	413	13	these	these	DET
fnp-3528	413	14	animal	animal	NOUN
fnp-3528	413	15	models	model	NOUN
fnp-3528	413	16	have	have	AUX
fnp-3528	413	17	contributed	contribute	VERB
fnp-3528	413	18	fundamentally	fundamentally	ADV
fnp-3528	413	19	to	to	ADP
fnp-3528	413	20	identifying	identify	VERB
fnp-3528	413	21	the	the	DET
fnp-3528	413	22	role	role	NOUN
fnp-3528	413	23	of	of	ADP
fnp-3528	413	24	abca	abca	NOUN
fnp-3528	413	25	transporters	transporter	NOUN
fnp-3528	413	26	in	in	ADP
fnp-3528	413	27	physiological	physiological	ADJ
fnp-3528	413	28	conditions	condition	NOUN
fnp-3528	413	29	as	as	ADV
fnp-3528	413	30	well	well	ADV
fnp-3528	413	31	as	as	ADP
fnp-3528	413	32	in	in	ADP
fnp-3528	413	33	disease	disease	NOUN
fnp-3528	413	34	pathogenesis	pathogenesis	NOUN
fnp-3528	413	35	.	.	PUNCT
fnp-3528	414	1	in	in	ADP
fnp-3528	414	2	addition	addition	NOUN
fnp-3528	414	3	,	,	PUNCT
fnp-3528	414	4	these	these	DET
fnp-3528	414	5	models	model	NOUN
fnp-3528	414	6	can	can	AUX
fnp-3528	414	7	be	be	AUX
fnp-3528	414	8	used	use	VERB
fnp-3528	414	9	for	for	ADP
fnp-3528	414	10	novel	novel	ADJ
fnp-3528	414	11	drug	drug	NOUN
fnp-3528	414	12	testing	testing	NOUN
fnp-3528	414	13	,	,	PUNCT
fnp-3528	414	14	as	as	SCONJ
fnp-3528	414	15	they	they	PRON
fnp-3528	414	16	provide	provide	VERB
fnp-3528	414	17	information	information	NOUN
fnp-3528	414	18	about	about	ADP
fnp-3528	414	19	target	target	NOUN
fnp-3528	414	20	specificity	specificity	NOUN
fnp-3528	414	21	.	.	PUNCT
fnp-3528	415	1	if	if	SCONJ
fnp-3528	415	2	a	a	DET
fnp-3528	415	3	drug	drug	NOUN
fnp-3528	415	4	is	be	AUX
fnp-3528	415	5	100	100	NUM
fnp-3528	415	6	%	%	NOUN
fnp-3528	415	7	specific	specific	ADJ
fnp-3528	415	8	for	for	ADP
fnp-3528	415	9	a	a	DET
fnp-3528	415	10	transporter	transporter	NOUN
fnp-3528	415	11	,	,	PUNCT
fnp-3528	415	12	knock	knock	NOUN
fnp-3528	415	13	-	-	PUNCT
fnp-3528	415	14	out	out	NOUN
fnp-3528	415	15	of	of	ADP
fnp-3528	415	16	this	this	DET
fnp-3528	415	17	transporter	transporter	NOUN
fnp-3528	415	18	should	should	AUX
fnp-3528	415	19	completely	completely	ADV
fnp-3528	415	20	abolish	abolish	VERB
fnp-3528	415	21	the	the	DET
fnp-3528	415	22	drug	drug	NOUN
fnp-3528	415	23	’s	’s	PART
fnp-3528	415	24	effects	effect	NOUN
fnp-3528	415	25	observed	observe	VERB
fnp-3528	415	26	in	in	ADP
fnp-3528	415	27	naïve	naïve	ADJ
fnp-3528	415	28	animals	animal	NOUN
fnp-3528	415	29	.	.	PUNCT
fnp-3528	416	1	however	however	ADV
fnp-3528	416	2	,	,	PUNCT
fnp-3528	416	3	gene	gene	NOUN
fnp-3528	416	4	knock	knock	NOUN
fnp-3528	416	5	-	-	PUNCT
fnp-3528	416	6	outs	out	NOUN
fnp-3528	416	7	often	often	ADV
fnp-3528	416	8	have	have	VERB
fnp-3528	416	9	phenotypical	phenotypical	ADJ
fnp-3528	416	10	effects	effect	NOUN
fnp-3528	416	11	per	per	ADP
fnp-3528	416	12	se	se	X
fnp-3528	416	13	that	that	PRON
fnp-3528	416	14	need	need	VERB
fnp-3528	416	15	to	to	PART
fnp-3528	416	16	be	be	AUX
fnp-3528	416	17	taken	take	VERB
fnp-3528	416	18	into	into	ADP
fnp-3528	416	19	account	account	NOUN
fnp-3528	416	20	when	when	SCONJ
fnp-3528	416	21	evaluating	evaluate	VERB
fnp-3528	416	22	drug	drug	NOUN
fnp-3528	416	23	effects	effect	NOUN
fnp-3528	416	24	.	.	PUNCT
fnp-3528	417	1	rnai	rnai	PROPN
fnp-3528	417	2	models	model	VERB
fnp-3528	417	3	the	the	DET
fnp-3528	417	4	use	use	NOUN
fnp-3528	417	5	of	of	ADP
fnp-3528	417	6	rna	rna	NOUN
fnp-3528	417	7	interference	interference	NOUN
fnp-3528	417	8	(	(	PUNCT
fnp-3528	417	9	rnai	rnai	PROPN
fnp-3528	417	10	)	)	PUNCT
fnp-3528	417	11	is	be	AUX
fnp-3528	417	12	an	an	DET
fnp-3528	417	13	alternative	alternative	NOUN
fnp-3528	417	14	to	to	PART
fnp-3528	417	15	knock	knock	VERB
fnp-3528	417	16	-	-	PUNCT
fnp-3528	417	17	out	out	ADP
fnp-3528	417	18	models	model	NOUN
fnp-3528	417	19	.	.	PUNCT
fnp-3528	418	1	this	this	DET
fnp-3528	418	2	technique	technique	NOUN
fnp-3528	418	3	is	be	AUX
fnp-3528	418	4	based	base	VERB
fnp-3528	418	5	on	on	ADP
fnp-3528	418	6	post	post	ADJ
fnp-3528	418	7	-	-	ADJ
fnp-3528	418	8	transcriptional	transcriptional	ADJ
fnp-3528	418	9	silencing	silencing	NOUN
fnp-3528	418	10	of	of	ADP
fnp-3528	418	11	the	the	DET
fnp-3528	418	12	targeted	target	VERB
fnp-3528	418	13	gene	gene	NOUN
fnp-3528	418	14	using	use	VERB
fnp-3528	418	15	sirna	sirna	PROPN
fnp-3528	418	16	molecules	molecule	NOUN
fnp-3528	418	17	that	that	PRON
fnp-3528	418	18	are	be	AUX
fnp-3528	418	19	designed	design	VERB
fnp-3528	418	20	to	to	PART
fnp-3528	418	21	bind	bind	VERB
fnp-3528	418	22	to	to	ADP
fnp-3528	418	23	the	the	DET
fnp-3528	418	24	target	target	NOUN
fnp-3528	418	25	mrna.538	mrna.538	NOUN
fnp-3528	418	26	this	this	DET
fnp-3528	418	27	process	process	NOUN
fnp-3528	418	28	will	will	AUX
fnp-3528	418	29	deactivate	deactivate	VERB
fnp-3528	418	30	the	the	DET
fnp-3528	418	31	mrna	mrna	NOUN
fnp-3528	418	32	using	use	VERB
fnp-3528	418	33	the	the	DET
fnp-3528	418	34	cell	cell	NOUN
fnp-3528	418	35	’s	’s	PART
fnp-3528	418	36	own	own	ADJ
fnp-3528	418	37	defense	defense	NOUN
fnp-3528	418	38	mechanism	mechanism	NOUN
fnp-3528	418	39	against	against	ADP
fnp-3528	418	40	pathogens	pathogen	NOUN
fnp-3528	418	41	.	.	PUNCT
fnp-3528	419	1	in	in	ADP
fnp-3528	419	2	contrast	contrast	NOUN
fnp-3528	419	3	to	to	ADP
fnp-3528	419	4	standard	standard	ADJ
fnp-3528	419	5	knock	knock	VERB
fnp-3528	419	6	-	-	PUNCT
fnp-3528	419	7	out	out	ADP
fnp-3528	419	8	models	model	NOUN
fnp-3528	419	9	,	,	PUNCT
fnp-3528	419	10	this	this	DET
fnp-3528	419	11	silencing	silencing	NOUN
fnp-3528	419	12	is	be	AUX
fnp-3528	419	13	temporary	temporary	ADJ
fnp-3528	419	14	as	as	SCONJ
fnp-3528	419	15	the	the	DET
fnp-3528	419	16	sirna	sirna	PROPN
fnp-3528	419	17	molecule	molecule	NOUN
fnp-3528	419	18	will	will	AUX
fnp-3528	419	19	be	be	AUX
fnp-3528	419	20	degraded	degrade	VERB
fnp-3528	419	21	but	but	CCONJ
fnp-3528	419	22	the	the	DET
fnp-3528	419	23	gene	gene	NOUN
fnp-3528	419	24	transcription	transcription	NOUN
fnp-3528	419	25	continues.527	continues.527	PRON
fnp-3528	419	26	to	to	PART
fnp-3528	419	27	avoid	avoid	VERB
fnp-3528	419	28	this	this	DET
fnp-3528	419	29	temporal	temporal	ADJ
fnp-3528	419	30	limitation	limitation	NOUN
fnp-3528	419	31	,	,	PUNCT
fnp-3528	419	32	short	short	ADJ
fnp-3528	419	33	-	-	PUNCT
fnp-3528	419	34	hairpin	hairpin	NOUN
fnp-3528	419	35	rna	rna	NOUN
fnp-3528	419	36	(	(	PUNCT
fnp-3528	419	37	shrna	shrna	NOUN
fnp-3528	419	38	)	)	PUNCT
fnp-3528	419	39	has	have	AUX
fnp-3528	419	40	been	be	AUX
fnp-3528	419	41	developed	develop	VERB
fnp-3528	419	42	.	.	PUNCT
fnp-3528	420	1	this	this	DET
fnp-3528	420	2	method	method	NOUN
fnp-3528	420	3	is	be	AUX
fnp-3528	420	4	based	base	VERB
fnp-3528	420	5	on	on	ADP
fnp-3528	420	6	the	the	DET
fnp-3528	420	7	use	use	NOUN
fnp-3528	420	8	of	of	ADP
fnp-3528	420	9	vectors	vector	NOUN
fnp-3528	420	10	that	that	PRON
fnp-3528	420	11	incorporate	incorporate	VERB
fnp-3528	420	12	into	into	ADP
fnp-3528	420	13	the	the	DET
fnp-3528	420	14	cell	cell	NOUN
fnp-3528	420	15	dna	dna	NOUN
fnp-3528	420	16	and	and	CCONJ
fnp-3528	420	17	encode	encode	VERB
fnp-3528	420	18	for	for	ADP
fnp-3528	420	19	shrna	shrna	NOUN
fnp-3528	420	20	.	.	PUNCT
fnp-3528	421	1	after	after	ADP
fnp-3528	421	2	transcription	transcription	NOUN
fnp-3528	421	3	,	,	PUNCT
fnp-3528	421	4	these	these	DET
fnp-3528	421	5	vectors	vector	NOUN
fnp-3528	421	6	are	be	AUX
fnp-3528	421	7	processed	process	VERB
fnp-3528	421	8	into	into	ADP
fnp-3528	421	9	sirna	sirna	PROPN
fnp-3528	421	10	.	.	PUNCT
fnp-3528	422	1	these	these	DET
fnp-3528	422	2	shrnas	shrna	NOUN
fnp-3528	422	3	are	be	AUX
fnp-3528	422	4	continuously	continuously	ADV
fnp-3528	422	5	transcribed	transcribe	VERB
fnp-3528	422	6	,	,	PUNCT
fnp-3528	422	7	increasing	increase	VERB
fnp-3528	422	8	reproducibility	reproducibility	NOUN
fnp-3528	422	9	of	of	ADP
fnp-3528	422	10	results.539	results.539	NOUN
fnp-3528	422	11	overexpression	overexpression	NOUN
fnp-3528	422	12	models	model	NOUN
fnp-3528	422	13	similar	similar	ADJ
fnp-3528	422	14	to	to	ADP
fnp-3528	422	15	knock	knock	VERB
fnp-3528	422	16	-	-	PUNCT
fnp-3528	422	17	out	out	ADP
fnp-3528	422	18	models	model	NOUN
fnp-3528	422	19	,	,	PUNCT
fnp-3528	422	20	overexpression	overexpression	NOUN
fnp-3528	422	21	models	model	NOUN
fnp-3528	422	22	can	can	AUX
fnp-3528	422	23	be	be	AUX
fnp-3528	422	24	used	use	VERB
fnp-3528	422	25	to	to	PART
fnp-3528	422	26	investigate	investigate	VERB
fnp-3528	422	27	the	the	DET
fnp-3528	422	28	function	function	NOUN
fnp-3528	422	29	of	of	ADP
fnp-3528	422	30	a	a	DET
fnp-3528	422	31	gene	gene	NOUN
fnp-3528	422	32	by	by	ADP
fnp-3528	422	33	evaluating	evaluate	VERB
fnp-3528	422	34	the	the	DET
fnp-3528	422	35	resultant	resultant	NOUN
fnp-3528	422	36	phenotype	phenotype	NOUN
fnp-3528	422	37	.	.	PUNCT
fnp-3528	423	1	in	in	ADP
fnp-3528	423	2	addition	addition	NOUN
fnp-3528	423	3	,	,	PUNCT
fnp-3528	423	4	overexpression	overexpression	NOUN
fnp-3528	423	5	models	model	NOUN
fnp-3528	423	6	have	have	AUX
fnp-3528	423	7	long	long	ADV
fnp-3528	423	8	been	be	AUX
fnp-3528	423	9	used	use	VERB
fnp-3528	423	10	for	for	ADP
fnp-3528	423	11	modeling	model	VERB
fnp-3528	423	12	diseases	disease	NOUN
fnp-3528	423	13	such	such	ADJ
fnp-3528	423	14	as	as	ADP
fnp-3528	423	15	ad540	ad540	PROPN
fnp-3528	423	16	or	or	CCONJ
fnp-3528	423	17	pd.541	pd.541	NOUN
fnp-3528	423	18	in	in	ADP
fnp-3528	423	19	the	the	DET
fnp-3528	423	20	investigation	investigation	NOUN
fnp-3528	423	21	of	of	ADP
fnp-3528	423	22	abca	abca	PROPN
fnp-3528	423	23	transporters	transporter	NOUN
fnp-3528	423	24	,	,	PUNCT
fnp-3528	423	25	these	these	DET
fnp-3528	423	26	models	model	NOUN
fnp-3528	423	27	can	can	AUX
fnp-3528	423	28	resemble	resemble	VERB
fnp-3528	423	29	the	the	DET
fnp-3528	423	30	effect	effect	NOUN
fnp-3528	423	31	of	of	ADP
fnp-3528	423	32	chronic	chronic	ADJ
fnp-3528	423	33	activation	activation	NOUN
fnp-3528	423	34	of	of	ADP
fnp-3528	423	35	the	the	DET
fnp-3528	423	36	transporters	transporter	NOUN
fnp-3528	423	37	and	and	CCONJ
fnp-3528	423	38	may	may	AUX
fnp-3528	423	39	help	help	VERB
fnp-3528	423	40	to	to	PART
fnp-3528	423	41	identify	identify	VERB
fnp-3528	423	42	its	its	PRON
fnp-3528	423	43	physiological	physiological	ADJ
fnp-3528	423	44	functions	function	NOUN
fnp-3528	423	45	by	by	ADP
fnp-3528	423	46	evaluating	evaluate	VERB
fnp-3528	423	47	the	the	DET
fnp-3528	423	48	pathways	pathway	NOUN
fnp-3528	423	49	upregulated	upregulate	VERB
fnp-3528	423	50	in	in	ADP
fnp-3528	423	51	comparison	comparison	NOUN
fnp-3528	423	52	to	to	ADP
fnp-3528	423	53	control	control	NOUN
fnp-3528	423	54	animals.127	animals.127	PROPN
fnp-3528	423	55	humanized	humanize	VERB
fnp-3528	423	56	abc	abc	PROPN
fnp-3528	423	57	transporter	transporter	NOUN
fnp-3528	423	58	mouse	mouse	NOUN
fnp-3528	423	59	models	model	NOUN
fnp-3528	423	60	before	before	SCONJ
fnp-3528	423	61	it	it	PRON
fnp-3528	423	62	can	can	AUX
fnp-3528	423	63	be	be	AUX
fnp-3528	423	64	translated	translate	VERB
fnp-3528	423	65	into	into	ADP
fnp-3528	423	66	clinical	clinical	ADJ
fnp-3528	423	67	practice	practice	NOUN
fnp-3528	423	68	,	,	PUNCT
fnp-3528	423	69	each	each	DET
fnp-3528	423	70	novel	novel	ADJ
fnp-3528	423	71	drug	drug	NOUN
fnp-3528	423	72	candidate	candidate	NOUN
fnp-3528	423	73	must	must	AUX
fnp-3528	423	74	be	be	AUX
fnp-3528	423	75	tested	test	VERB
fnp-3528	423	76	in	in	ADP
fnp-3528	423	77	an	an	DET
fnp-3528	423	78	in	in	ADP
fnp-3528	423	79	vivo	vivo	NOUN
fnp-3528	423	80	model	model	NOUN
fnp-3528	423	81	.	.	PUNCT
fnp-3528	424	1	however	however	ADV
fnp-3528	424	2	,	,	PUNCT
fnp-3528	424	3	the	the	DET
fnp-3528	424	4	translational	translational	ADJ
fnp-3528	424	5	value	value	NOUN
fnp-3528	424	6	of	of	ADP
fnp-3528	424	7	the	the	DET
fnp-3528	424	8	animal	animal	NOUN
fnp-3528	424	9	model	model	NOUN
fnp-3528	424	10	largely	largely	ADV
fnp-3528	424	11	depends	depend	VERB
fnp-3528	424	12	on	on	ADP
fnp-3528	424	13	whether	whether	SCONJ
fnp-3528	424	14	the	the	DET
fnp-3528	424	15	disease	disease	NOUN
fnp-3528	424	16	pathway	pathway	NOUN
fnp-3528	424	17	under	under	ADP
fnp-3528	424	18	investigation	investigation	NOUN
fnp-3528	424	19	is	be	AUX
fnp-3528	424	20	conserved	conserve	VERB
fnp-3528	424	21	between	between	ADP
fnp-3528	424	22	the	the	DET
fnp-3528	424	23	two	two	NUM
fnp-3528	424	24	species	specie	NOUN
fnp-3528	424	25	.	.	PUNCT
fnp-3528	425	1	therefore	therefore	ADV
fnp-3528	425	2	,	,	PUNCT
fnp-3528	425	3	replacing	replace	VERB
fnp-3528	425	4	the	the	DET
fnp-3528	425	5	original	original	ADJ
fnp-3528	425	6	(	(	PUNCT
fnp-3528	425	7	e.g.	e.g.	ADJ
fnp-3528	425	8	,	,	PUNCT
fnp-3528	425	9	murine	murine	ADJ
fnp-3528	425	10	)	)	PUNCT
fnp-3528	425	11	gene	gene	NOUN
fnp-3528	425	12	by	by	ADP
fnp-3528	425	13	the	the	DET
fnp-3528	425	14	respective	respective	ADJ
fnp-3528	425	15	human	human	ADJ
fnp-3528	425	16	gene	gene	NOUN
fnp-3528	425	17	likely	likely	ADV
fnp-3528	425	18	improves	improve	VERB
fnp-3528	425	19	the	the	DET
fnp-3528	425	20	animal	animal	NOUN
fnp-3528	425	21	model	model	NOUN
fnp-3528	425	22	,	,	PUNCT
fnp-3528	425	23	and	and	CCONJ
fnp-3528	425	24	thus	thus	ADV
fnp-3528	425	25	,	,	PUNCT
fnp-3528	425	26	is	be	AUX
fnp-3528	425	27	beneficial	beneficial	ADJ
fnp-3528	425	28	for	for	ADP
fnp-3528	425	29	evaluating	evaluate	VERB
fnp-3528	425	30	a	a	DET
fnp-3528	425	31	novel	novel	ADJ
fnp-3528	425	32	drug	drug	NOUN
fnp-3528	425	33	’s	’s	PART
fnp-3528	425	34	efficacy	efficacy	NOUN
fnp-3528	425	35	and	and	CCONJ
fnp-3528	425	36	specificity	specificity	NOUN
fnp-3528	425	37	in	in	ADP
fnp-3528	425	38	clinical	clinical	ADJ
fnp-3528	425	39	practice.542	practice.542	NOUN
fnp-3528	425	40	with	with	ADP
fnp-3528	425	41	this	this	DET
fnp-3528	425	42	approach	approach	NOUN
fnp-3528	425	43	,	,	PUNCT
fnp-3528	425	44	mice	mouse	NOUN
fnp-3528	425	45	can	can	AUX
fnp-3528	425	46	be	be	AUX
fnp-3528	425	47	used	use	VERB
fnp-3528	425	48	as	as	ADP
fnp-3528	425	49	tools	tool	NOUN
fnp-3528	425	50	for	for	ADP
fnp-3528	425	51	pre	pre	ADJ
fnp-3528	425	52	-	-	ADJ
fnp-3528	425	53	clinical	clinical	ADJ
fnp-3528	425	54	screening	screening	NOUN
fnp-3528	425	55	and	and	CCONJ
fnp-3528	425	56	efficacy	efficacy	NOUN
fnp-3528	425	57	evaluation	evaluation	NOUN
fnp-3528	425	58	of	of	ADP
fnp-3528	425	59	new	new	ADJ
fnp-3528	425	60	drugs	drug	NOUN
fnp-3528	425	61	,	,	PUNCT
fnp-3528	425	62	given	give	VERB
fnp-3528	425	63	their	their	PRON
fnp-3528	425	64	improved	improve	VERB
fnp-3528	425	65	ability	ability	NOUN
fnp-3528	425	66	to	to	PART
fnp-3528	425	67	predict	predict	VERB
fnp-3528	425	68	human	human	ADJ
fnp-3528	425	69	responses	response	NOUN
fnp-3528	425	70	to	to	ADP
fnp-3528	425	71	treatments	treatment	NOUN
fnp-3528	425	72	.	.	PUNCT
fnp-3528	426	1	our	our	PRON
fnp-3528	426	2	group	group	NOUN
fnp-3528	426	3	has	have	AUX
fnp-3528	426	4	previously	previously	ADV
fnp-3528	426	5	established	establish	VERB
fnp-3528	426	6	a	a	DET
fnp-3528	426	7	humanized	humanize	VERB
fnp-3528	426	8	abcc1	abcc1	PROPN
fnp-3528	426	9	mouse	mouse	PROPN
fnp-3528	426	10	model,543	model,543	PROPN
fnp-3528	426	11	and	and	CCONJ
fnp-3528	426	12	an	an	DET
fnp-3528	426	13	abca7	abca7	PROPN
fnp-3528	426	14	model	model	NOUN
fnp-3528	426	15	is	be	AUX
fnp-3528	426	16	under	under	ADP
fnp-3528	426	17	characterization	characterization	NOUN
fnp-3528	426	18	.	.	PUNCT
fnp-3528	427	1	here	here	ADV
fnp-3528	427	2	,	,	PUNCT
fnp-3528	427	3	we	we	PRON
fnp-3528	427	4	generated	generate	VERB
fnp-3528	427	5	knock	knock	NOUN
fnp-3528	427	6	-	-	PUNCT
fnp-3528	427	7	in	in	ADP
fnp-3528	427	8	mouse	mouse	NOUN
fnp-3528	427	9	models	model	NOUN
fnp-3528	427	10	producing	produce	VERB
fnp-3528	427	11	a	a	DET
fnp-3528	427	12	chimeric	chimeric	ADJ
fnp-3528	427	13	protein	protein	NOUN
fnp-3528	427	14	that	that	PRON
fnp-3528	427	15	is	be	AUX
fnp-3528	427	16	completely	completely	ADV
fnp-3528	427	17	human	human	ADJ
fnp-3528	427	18	except	except	SCONJ
fnp-3528	427	19	for	for	ADP
fnp-3528	427	20	one	one	NUM
fnp-3528	427	21	amino	amino	NOUN
fnp-3528	427	22	acid.543	acid.543	NOUN
fnp-3528	427	23	in	in	ADP
fnp-3528	427	24	addition	addition	NOUN
fnp-3528	427	25	,	,	PUNCT
fnp-3528	427	26	as	as	SCONJ
fnp-3528	427	27	this	this	DET
fnp-3528	427	28	gene	gene	NOUN
fnp-3528	427	29	was	be	AUX
fnp-3528	427	30	flanked	flank	VERB
fnp-3528	427	31	by	by	ADP
fnp-3528	427	32	loxp	loxp	ADJ
fnp-3528	427	33	sites	site	NOUN
fnp-3528	427	34	,	,	PUNCT
fnp-3528	427	35	this	this	DET
fnp-3528	427	36	humanized	humanize	VERB
fnp-3528	427	37	model	model	NOUN
fnp-3528	427	38	can	can	AUX
fnp-3528	427	39	be	be	AUX
fnp-3528	427	40	knocked	knock	VERB
fnp-3528	427	41	out	out	ADP
fnp-3528	427	42	in	in	ADP
fnp-3528	427	43	specific	specific	ADJ
fnp-3528	427	44	cell	cell	NOUN
fnp-3528	427	45	populations	population	NOUN
fnp-3528	427	46	and	and	CCONJ
fnp-3528	427	47	at	at	ADP
fnp-3528	427	48	a	a	DET
fnp-3528	427	49	specific	specific	ADJ
fnp-3528	427	50	age.543	age.543	ADJ
fnp-3528	427	51	models	model	NOUN
fnp-3528	427	52	such	such	ADJ
fnp-3528	427	53	as	as	ADP
fnp-3528	427	54	these	these	PRON
fnp-3528	427	55	represent	represent	VERB
fnp-3528	427	56	the	the	DET
fnp-3528	427	57	future	future	NOUN
fnp-3528	427	58	of	of	ADP
fnp-3528	427	59	pre	pre	ADJ
fnp-3528	427	60	-	-	ADJ
fnp-3528	427	61	clinical	clinical	ADJ
fnp-3528	427	62	drug	drug	NOUN
fnp-3528	427	63	candidate	candidate	NOUN
fnp-3528	427	64	evaluation	evaluation	NOUN
fnp-3528	427	65	.	.	PUNCT
fnp-3528	428	1	in	in	ADP
fnp-3528	428	2	addition	addition	NOUN
fnp-3528	428	3	,	,	PUNCT
fnp-3528	428	4	dallas	dallas	PROPN
fnp-3528	428	5	et	et	PROPN
fnp-3528	428	6	al	al	PROPN
fnp-3528	428	7	.	.	PROPN
fnp-3528	428	8	successfully	successfully	ADV
fnp-3528	428	9	generated	generate	VERB
fnp-3528	428	10	a	a	DET
fnp-3528	428	11	humanized	humanized	ADJ
fnp-3528	428	12	abcg2	abcg2	NOUN
fnp-3528	428	13	mouse	mouse	NOUN
fnp-3528	428	14	model.544	model.544	PROPN
fnp-3528	428	15	however	however	ADV
fnp-3528	428	16	,	,	PUNCT
fnp-3528	428	17	other	other	ADJ
fnp-3528	428	18	models	model	NOUN
fnp-3528	428	19	,	,	PUNCT
fnp-3528	428	20	such	such	ADJ
fnp-3528	428	21	as	as	ADP
fnp-3528	428	22	humanized	humanize	VERB
fnp-3528	428	23	abcb1	abcb1	NOUN
fnp-3528	428	24	mice	mouse	NOUN
fnp-3528	428	25	,	,	PUNCT
fnp-3528	428	26	were	be	AUX
fnp-3528	428	27	not	not	PART
fnp-3528	428	28	successful	successful	ADJ
fnp-3528	428	29	despite	despite	SCONJ
fnp-3528	428	30	multiple	multiple	ADJ
fnp-3528	428	31	attempts.545	attempts.545	PROPN
fnp-3528	428	32	disease	disease	NOUN
fnp-3528	428	33	models	model	NOUN
fnp-3528	428	34	in	in	ADP
fnp-3528	428	35	addition	addition	NOUN
fnp-3528	428	36	,	,	PUNCT
fnp-3528	428	37	all	all	DET
fnp-3528	428	38	the	the	DET
fnp-3528	428	39	models	model	NOUN
fnp-3528	428	40	described	describe	VERB
fnp-3528	428	41	above	above	ADV
fnp-3528	428	42	can	can	AUX
fnp-3528	428	43	also	also	ADV
fnp-3528	428	44	be	be	AUX
fnp-3528	428	45	used	use	VERB
fnp-3528	428	46	to	to	PART
fnp-3528	428	47	study	study	VERB
fnp-3528	428	48	the	the	DET
fnp-3528	428	49	role	role	NOUN
fnp-3528	428	50	of	of	ADP
fnp-3528	428	51	a	a	DET
fnp-3528	428	52	gene	gene	NOUN
fnp-3528	428	53	for	for	ADP
fnp-3528	428	54	the	the	DET
fnp-3528	428	55	pathophysiology	pathophysiology	NOUN
fnp-3528	428	56	of	of	ADP
fnp-3528	428	57	specific	specific	ADJ
fnp-3528	428	58	diseases	disease	NOUN
fnp-3528	428	59	.	.	PUNCT
fnp-3528	429	1	for	for	ADP
fnp-3528	429	2	example	example	NOUN
fnp-3528	429	3	,	,	PUNCT
fnp-3528	429	4	abca	abca	NOUN
fnp-3528	429	5	knock	knock	NOUN
fnp-3528	429	6	-	-	PUNCT
fnp-3528	429	7	out	out	ADP
fnp-3528	429	8	models	model	NOUN
fnp-3528	429	9	have	have	AUX
fnp-3528	429	10	been	be	AUX
fnp-3528	429	11	crossed	cross	VERB
fnp-3528	429	12	with	with	ADP
fnp-3528	429	13	transgenic	transgenic	NOUN
fnp-3528	429	14	mice	mouse	NOUN
fnp-3528	429	15	in	in	ADP
fnp-3528	429	16	order	order	NOUN
fnp-3528	429	17	to	to	PART
fnp-3528	429	18	study	study	VERB
fnp-3528	429	19	their	their	PRON
fnp-3528	429	20	potential	potential	ADJ
fnp-3528	429	21	role	role	NOUN
fnp-3528	429	22	in	in	ADP
fnp-3528	429	23	ad.54,123,131,161	ad.54,123,131,161	VERB
fnp-3528	429	24	-	-	SYM
fnp-3528	429	25	163,527	163,527	NUM
fnp-3528	429	26	these	these	DET
fnp-3528	429	27	studies	study	NOUN
fnp-3528	429	28	have	have	AUX
fnp-3528	429	29	elucidated	elucidate	VERB
fnp-3528	429	30	potential	potential	ADJ
fnp-3528	429	31	disease	disease	NOUN
fnp-3528	429	32	mechanisms	mechanism	NOUN
fnp-3528	429	33	involving	involve	VERB
fnp-3528	429	34	abca	abca	NOUN
fnp-3528	429	35	transporters	transporter	NOUN
fnp-3528	429	36	that	that	PRON
fnp-3528	429	37	can	can	AUX
fnp-3528	429	38	not	not	PART
fnp-3528	429	39	be	be	AUX
fnp-3528	429	40	studied	study	VERB
fnp-3528	429	41	in	in	ADP
fnp-3528	429	42	patients	patient	NOUN
fnp-3528	429	43	.	.	PUNCT
fnp-3528	430	1	moreover	moreover	ADV
fnp-3528	430	2	,	,	PUNCT
fnp-3528	430	3	once	once	ADV
fnp-3528	430	4	a	a	DET
fnp-3528	430	5	drug	drug	NOUN
fnp-3528	430	6	is	be	AUX
fnp-3528	430	7	developed	develop	VERB
fnp-3528	430	8	and	and	CCONJ
fnp-3528	430	9	its	its	PRON
fnp-3528	430	10	specificity	specificity	NOUN
fnp-3528	430	11	is	be	AUX
fnp-3528	430	12	proven	prove	VERB
fnp-3528	430	13	,	,	PUNCT
fnp-3528	430	14	disease	disease	NOUN
fnp-3528	430	15	models	model	NOUN
fnp-3528	430	16	enable	enable	VERB
fnp-3528	430	17	evaluation	evaluation	NOUN
fnp-3528	430	18	of	of	ADP
fnp-3528	430	19	the	the	DET
fnp-3528	430	20	role	role	NOUN
fnp-3528	430	21	of	of	ADP
fnp-3528	430	22	that	that	DET
fnp-3528	430	23	specific	specific	ADJ
fnp-3528	430	24	transporter	transporter	NOUN
fnp-3528	430	25	in	in	ADP
fnp-3528	430	26	the	the	DET
fnp-3528	430	27	pathophysiology	pathophysiology	NOUN
fnp-3528	430	28	of	of	ADP
fnp-3528	430	29	the	the	DET
fnp-3528	430	30	disease	disease	NOUN
fnp-3528	430	31	.	.	PUNCT
fnp-3528	431	1	at	at	ADP
fnp-3528	431	2	the	the	DET
fnp-3528	431	3	same	same	ADJ
fnp-3528	431	4	time	time	NOUN
fnp-3528	431	5	,	,	PUNCT
fnp-3528	431	6	these	these	DET
fnp-3528	431	7	results	result	NOUN
fnp-3528	431	8	may	may	AUX
fnp-3528	431	9	be	be	AUX
fnp-3528	431	10	the	the	DET
fnp-3528	431	11	first	first	ADJ
fnp-3528	431	12	step	step	NOUN
fnp-3528	431	13	to	to	PART
fnp-3528	431	14	evaluate	evaluate	VERB
fnp-3528	431	15	the	the	DET
fnp-3528	431	16	potential	potential	NOUN
fnp-3528	431	17	of	of	ADP
fnp-3528	431	18	novel	novel	ADJ
fnp-3528	431	19	transporter	transporter	NOUN
fnp-3528	431	20	modulators	modulator	NOUN
fnp-3528	431	21	as	as	ADP
fnp-3528	431	22	therapy	therapy	NOUN
fnp-3528	431	23	for	for	ADP
fnp-3528	431	24	the	the	DET
fnp-3528	431	25	respective	respective	ADJ
fnp-3528	431	26	disease	disease	NOUN
fnp-3528	431	27	.	.	PUNCT
fnp-3528	432	1	imaging	imaging	NOUN
fnp-3528	432	2	techniques	technique	NOUN
fnp-3528	432	3	lastly	lastly	ADV
fnp-3528	432	4	,	,	PUNCT
fnp-3528	432	5	in	in	ADP
fnp-3528	432	6	vivo	vivo	ADJ
fnp-3528	432	7	imaging	imaging	NOUN
fnp-3528	432	8	can	can	AUX
fnp-3528	432	9	be	be	AUX
fnp-3528	432	10	used	use	VERB
fnp-3528	432	11	for	for	ADP
fnp-3528	432	12	the	the	DET
fnp-3528	432	13	development	development	NOUN
fnp-3528	432	14	of	of	ADP
fnp-3528	432	15	new	new	ADJ
fnp-3528	432	16	drugs	drug	NOUN
fnp-3528	432	17	.	.	PUNCT
fnp-3528	433	1	on	on	ADP
fnp-3528	433	2	the	the	DET
fnp-3528	433	3	one	one	NUM
fnp-3528	433	4	hand	hand	NOUN
fnp-3528	433	5	,	,	PUNCT
fnp-3528	433	6	labeling	label	VERB
fnp-3528	433	7	drug	drug	NOUN
fnp-3528	433	8	candidates	candidate	NOUN
fnp-3528	433	9	with	with	ADP
fnp-3528	433	10	radioactive	radioactive	ADJ
fnp-3528	433	11	isotopes	isotope	NOUN
fnp-3528	433	12	can	can	AUX
fnp-3528	433	13	give	give	VERB
fnp-3528	433	14	information	information	NOUN
fnp-3528	433	15	about	about	ADP
fnp-3528	433	16	the	the	DET
fnp-3528	433	17	drug	drug	NOUN
fnp-3528	433	18	distribution	distribution	NOUN
fnp-3528	433	19	,	,	PUNCT
fnp-3528	433	20	drug	drug	NOUN
fnp-3528	433	21	target	target	NOUN
fnp-3528	433	22	,	,	PUNCT
fnp-3528	433	23	and	and	CCONJ
fnp-3528	433	24	drug	drug	NOUN
fnp-3528	433	25	metabolism	metabolism	NOUN
fnp-3528	433	26	in	in	ADP
fnp-3528	433	27	vivo	vivo	NOUN
fnp-3528	433	28	.	.	PUNCT
fnp-3528	434	1	in	in	ADP
fnp-3528	434	2	addition	addition	NOUN
fnp-3528	434	3	,	,	PUNCT
fnp-3528	434	4	it	it	PRON
fnp-3528	434	5	can	can	AUX
fnp-3528	434	6	also	also	ADV
fnp-3528	434	7	show	show	VERB
fnp-3528	434	8	whether	whether	SCONJ
fnp-3528	434	9	a	a	DET
fnp-3528	434	10	drug	drug	NOUN
fnp-3528	434	11	is	be	AUX
fnp-3528	434	12	able	able	ADJ
fnp-3528	434	13	to	to	PART
fnp-3528	434	14	cross	cross	VERB
fnp-3528	434	15	specific	specific	ADJ
fnp-3528	434	16	natural	natural	ADJ
fnp-3528	434	17	barriers	barrier	NOUN
fnp-3528	434	18	,	,	PUNCT
fnp-3528	434	19	such	such	ADJ
fnp-3528	434	20	as	as	ADP
fnp-3528	434	21	the	the	DET
fnp-3528	434	22	bbb	bbb	PROPN
fnp-3528	434	23	.	.	PUNCT
fnp-3528	435	1	in	in	ADP
fnp-3528	435	2	vivo	vivo	ADJ
fnp-3528	435	3	imaging	imaging	NOUN
fnp-3528	435	4	can	can	AUX
fnp-3528	435	5	help	help	VERB
fnp-3528	435	6	to	to	PART
fnp-3528	435	7	select	select	VERB
fnp-3528	435	8	candidates	candidate	NOUN
fnp-3528	435	9	that	that	PRON
fnp-3528	435	10	appear	appear	VERB
fnp-3528	435	11	successful	successful	ADJ
fnp-3528	435	12	or	or	CCONJ
fnp-3528	435	13	to	to	PART
fnp-3528	435	14	discard	discard	VERB
fnp-3528	435	15	drugs	drug	NOUN
fnp-3528	435	16	that	that	PRON
fnp-3528	435	17	seem	seem	VERB
fnp-3528	435	18	likely	likely	ADJ
fnp-3528	435	19	to	to	PART
fnp-3528	435	20	fail.546	fail.546	VERB
fnp-3528	435	21	on	on	ADP
fnp-3528	435	22	the	the	DET
fnp-3528	435	23	other	other	ADJ
fnp-3528	435	24	hand	hand	NOUN
fnp-3528	435	25	,	,	PUNCT
fnp-3528	435	26	drug	drug	NOUN
fnp-3528	435	27	candidates	candidate	NOUN
fnp-3528	435	28	can	can	AUX
fnp-3528	435	29	also	also	ADV
fnp-3528	435	30	be	be	AUX
fnp-3528	435	31	used	use	VERB
fnp-3528	435	32	to	to	PART
fnp-3528	435	33	develop	develop	VERB
fnp-3528	435	34	new	new	ADJ
fnp-3528	435	35	radiotracers	radiotracer	NOUN
fnp-3528	435	36	(	(	PUNCT
fnp-3528	435	37	e.g.	e.g.	ADV
fnp-3528	435	38	,	,	PUNCT
fnp-3528	435	39	pet	pet	ADJ
fnp-3528	435	40	tracers	tracer	NOUN
fnp-3528	435	41	)	)	PUNCT
fnp-3528	435	42	targeting	target	VERB
fnp-3528	435	43	abca	abca	NOUN
fnp-3528	435	44	transporters	transporter	NOUN
fnp-3528	435	45	that	that	PRON
fnp-3528	435	46	could	could	AUX
fnp-3528	435	47	then	then	ADV
fnp-3528	435	48	be	be	AUX
fnp-3528	435	49	used	use	VERB
fnp-3528	435	50	in	in	ADP
fnp-3528	435	51	clinical	clinical	ADJ
fnp-3528	435	52	diagnostics	diagnostic	NOUN
fnp-3528	435	53	.	.	PUNCT
fnp-3528	436	1	radiotracers	radiotracer	NOUN
fnp-3528	436	2	would	would	AUX
fnp-3528	436	3	facilitate	facilitate	VERB
fnp-3528	436	4	the	the	DET
fnp-3528	436	5	study	study	NOUN
fnp-3528	436	6	of	of	ADP
fnp-3528	436	7	the	the	DET
fnp-3528	436	8	specific	specific	ADJ
fnp-3528	436	9	gene	gene	NOUN
fnp-3528	436	10	and/or	and/or	CCONJ
fnp-3528	436	11	its	its	PRON
fnp-3528	436	12	product	product	NOUN
fnp-3528	436	13	protein	protein	NOUN
fnp-3528	436	14	in	in	ADP
fnp-3528	436	15	human	human	ADJ
fnp-3528	436	16	patients	patient	NOUN
fnp-3528	436	17	in	in	ADP
fnp-3528	436	18	vivo	vivo	NOUN
fnp-3528	436	19	and	and	CCONJ
fnp-3528	436	20	in	in	ADP
fnp-3528	436	21	a	a	DET
fnp-3528	436	22	longitudinal	longitudinal	ADJ
fnp-3528	436	23	fashion	fashion	NOUN
fnp-3528	436	24	,	,	PUNCT
fnp-3528	436	25	enabling	enable	VERB
fnp-3528	436	26	a	a	DET
fnp-3528	436	27	much	much	ADV
fnp-3528	436	28	better	well	ADJ
fnp-3528	436	29	understanding	understanding	NOUN
fnp-3528	436	30	of	of	ADP
fnp-3528	436	31	the	the	DET
fnp-3528	436	32	role	role	NOUN
fnp-3528	436	33	of	of	ADP
fnp-3528	436	34	abca	abca	NOUN
fnp-3528	436	35	transporters	transporter	NOUN
fnp-3528	436	36	in	in	ADP
fnp-3528	436	37	human	human	NOUN
fnp-3528	436	38	(	(	PUNCT
fnp-3528	436	39	patho)physiology.547	patho)physiology.547	PROPN
fnp-3528	436	40	in	in	ADP
fnp-3528	436	41	this	this	DET
fnp-3528	436	42	regard	regard	NOUN
fnp-3528	436	43	,	,	PUNCT
fnp-3528	436	44	knock	knock	NOUN
fnp-3528	436	45	-	-	PUNCT
fnp-3528	436	46	out	out	ADP
fnp-3528	436	47	animals	animal	NOUN
fnp-3528	436	48	can	can	AUX
fnp-3528	436	49	be	be	AUX
fnp-3528	436	50	used	use	VERB
fnp-3528	436	51	as	as	ADP
fnp-3528	436	52	negative	negative	ADJ
fnp-3528	436	53	controls	control	NOUN
fnp-3528	436	54	for	for	ADP
fnp-3528	436	55	the	the	DET
fnp-3528	436	56	development	development	NOUN
fnp-3528	436	57	of	of	ADP
fnp-3528	436	58	new	new	ADJ
fnp-3528	436	59	abca	abca	NOUN
fnp-3528	436	60	radiotracers	radiotracer	NOUN
fnp-3528	436	61	to	to	PART
fnp-3528	436	62	evaluate	evaluate	VERB
fnp-3528	436	63	the	the	DET
fnp-3528	436	64	specificity	specificity	NOUN
fnp-3528	436	65	of	of	ADP
fnp-3528	436	66	the	the	DET
fnp-3528	436	67	radiotracer.548	radiotracer.548	NOUN
fnp-3528	436	68	furthermore	furthermore	ADV
fnp-3528	436	69	,	,	PUNCT
fnp-3528	436	70	these	these	DET
fnp-3528	436	71	very	very	ADV
fnp-3528	436	72	same	same	ADJ
fnp-3528	436	73	radiotracers	radiotracer	NOUN
fnp-3528	436	74	can	can	AUX
fnp-3528	436	75	be	be	AUX
fnp-3528	436	76	used	use	VERB
fnp-3528	436	77	in	in	ADP
fnp-3528	436	78	animal	animal	NOUN
fnp-3528	436	79	disease	disease	NOUN
fnp-3528	436	80	models	model	NOUN
fnp-3528	436	81	,	,	PUNCT
fnp-3528	436	82	enabling	enable	VERB
fnp-3528	436	83	longitudinal	longitudinal	ADJ
fnp-3528	436	84	studies	study	NOUN
fnp-3528	436	85	and	and	CCONJ
fnp-3528	436	86	reducing	reduce	VERB
fnp-3528	436	87	the	the	DET
fnp-3528	436	88	number	number	NOUN
fnp-3528	436	89	of	of	ADP
fnp-3528	436	90	animals	animal	NOUN
fnp-3528	436	91	required.549	required.549	ADJ
fnp-3528	436	92	-	-	ADJ
fnp-3528	436	93	551	551	NUM
fnp-3528	436	94	concluding	concluding	NOUN
fnp-3528	436	95	remarks	remark	VERB
fnp-3528	436	96	:	:	PUNCT
fnp-3528	436	97	where	where	SCONJ
fnp-3528	436	98	do	do	AUX
fnp-3528	436	99	we	we	PRON
fnp-3528	436	100	go	go	VERB
fnp-3528	436	101	from	from	ADP
fnp-3528	436	102	here	here	ADV
fnp-3528	436	103	?	?	PUNCT
fnp-3528	437	1	several	several	ADJ
fnp-3528	437	2	in	in	ADP
fnp-3528	437	3	vivo	vivo	ADJ
fnp-3528	437	4	studies	study	NOUN
fnp-3528	437	5	demonstrated	demonstrate	VERB
fnp-3528	437	6	that	that	SCONJ
fnp-3528	437	7	modulators	modulator	NOUN
fnp-3528	437	8	of	of	ADP
fnp-3528	437	9	abca	abca	NOUN
fnp-3528	437	10	transporters	transporter	NOUN
fnp-3528	437	11	,	,	PUNCT
fnp-3528	437	12	in	in	ADP
fnp-3528	437	13	particular	particular	ADJ
fnp-3528	437	14	abca1	abca1	NOUN
fnp-3528	437	15	,	,	PUNCT
fnp-3528	437	16	have	have	VERB
fnp-3528	437	17	systemic	systemic	ADJ
fnp-3528	437	18	effects.231,249,250,253,271,275,289,293,297,330,335,344,350,361,362,366,368	effects.231,249,250,253,271,275,289,293,297,330,335,344,350,361,362,366,368	PROPN
fnp-3528	437	19	-	-	PUNCT
fnp-3528	437	20	370,376,378,383,410,415,417	370,376,378,383,410,415,417	NUM
fnp-3528	437	21	-	-	PUNCT
fnp-3528	437	22	419,425,431,436,448	419,425,431,436,448	NOUN
fnp-3528	437	23	however	however	ADV
fnp-3528	437	24	,	,	PUNCT
fnp-3528	437	25	the	the	DET
fnp-3528	437	26	vast	vast	ADJ
fnp-3528	437	27	majority	majority	NOUN
fnp-3528	437	28	of	of	ADP
fnp-3528	437	29	these	these	DET
fnp-3528	437	30	modulators	modulator	NOUN
fnp-3528	437	31	were	be	AUX
fnp-3528	437	32	regulators,231,250,253,271,297,330,335,344,350,361,362,366,368	regulators,231,250,253,271,297,330,335,344,350,361,362,366,368	NOUN
fnp-3528	437	33	-	-	PUNCT
fnp-3528	437	34	370	370	NUM
fnp-3528	437	35	,	,	PUNCT
fnp-3528	437	36	376,378,383,410,415,417	376,378,383,410,415,417	NOUN
fnp-3528	437	37	-	-	PUNCT
fnp-3528	437	38	419,425,431,436,448	419,425,431,436,448	PRON
fnp-3528	437	39	specifically	specifically	ADV
fnp-3528	437	40	inducers,250,253,271,297,330,344,361,362,366,368	inducers,250,253,271,297,330,344,361,362,366,368	NOUN
fnp-3528	437	41	-	-	PUNCT
fnp-3528	437	42	370,376,378,383,410	370,376,378,383,410	NUM
fnp-3528	437	43	,	,	PUNCT
fnp-3528	437	44	415,418,419,425,431	415,418,419,425,431	NUM
fnp-3528	437	45	and	and	CCONJ
fnp-3528	437	46	only	only	ADV
fnp-3528	437	47	very	very	ADV
fnp-3528	437	48	few	few	ADJ
fnp-3528	437	49	interactors	interactor	NOUN
fnp-3528	437	50	demonstrated	demonstrate	VERB
fnp-3528	437	51	in	in	ADP
fnp-3528	437	52	vivo	vivo	NOUN
fnp-3528	437	53	effects.249,289,293	effects.249,289,293	NOUN
fnp-3528	437	54	mostly	mostly	ADV
fnp-3528	437	55	emphasizing	emphasize	VERB
fnp-3528	437	56	atherosclerosis,249,275,289,366,369,370,378,410,417	atherosclerosis,249,275,289,366,369,370,378,410,417	PROPN
fnp-3528	437	57	-	-	PUNCT
fnp-3528	437	58	419,425,431,448	419,425,431,448	NUM
fnp-3528	437	59	these	these	DET
fnp-3528	437	60	regulators	regulator	NOUN
fnp-3528	437	61	were	be	AUX
fnp-3528	437	62	able	able	ADJ
fnp-3528	437	63	to	to	PART
fnp-3528	437	64	demonstrate	demonstrate	VERB
fnp-3528	437	65	that	that	SCONJ
fnp-3528	437	66	cellular	cellular	ADJ
fnp-3528	437	67	and	and	CCONJ
fnp-3528	437	68	plasma	plasma	NOUN
fnp-3528	437	69	lipid	lipid	NOUN
fnp-3528	437	70	content249,271,275,289,330,366,369,378,419,425,431	content249,271,275,289,330,366,369,378,419,425,431	PROPN
fnp-3528	437	71	as	as	ADV
fnp-3528	437	72	well	well	ADV
fnp-3528	437	73	as	as	ADP
fnp-3528	437	74	atherosclerotic	atherosclerotic	ADJ
fnp-3528	437	75	plaque	plaque	NOUN
fnp-3528	437	76	formation275,289,366,369,370,410	formation275,289,366,369,370,410	PROPN
fnp-3528	437	77	,	,	PUNCT
fnp-3528	437	78	417	417	NUM
fnp-3528	437	79	-	-	SYM
fnp-3528	437	80	419,425,448	419,425,448	NUM
fnp-3528	437	81	could	could	AUX
fnp-3528	437	82	be	be	AUX
fnp-3528	437	83	changed	change	VERB
fnp-3528	437	84	compared	compare	VERB
fnp-3528	437	85	to	to	ADP
fnp-3528	437	86	controls	control	NOUN
fnp-3528	437	87	(	(	PUNCT
fnp-3528	437	88	enhanced	enhance	VERB
fnp-3528	437	89	or	or	CCONJ
fnp-3528	437	90	reduced	reduce	VERB
fnp-3528	437	91	)	)	PUNCT
fnp-3528	437	92	after	after	ADP
fnp-3528	437	93	treatment	treatment	NOUN
fnp-3528	437	94	with	with	ADP
fnp-3528	437	95	the	the	DET
fnp-3528	437	96	respective	respective	ADJ
fnp-3528	437	97	drug	drug	NOUN
fnp-3528	437	98	.	.	PUNCT
fnp-3528	438	1	only	only	ADV
fnp-3528	438	2	very	very	ADV
fnp-3528	438	3	few	few	ADJ
fnp-3528	438	4	in	in	ADP
fnp-3528	438	5	vivo	vivo	ADJ
fnp-3528	438	6	approaches	approach	NOUN
fnp-3528	438	7	targeted	target	VERB
fnp-3528	438	8	for	for	ADP
fnp-3528	438	9	ad.293,297,344,383	ad.293,297,344,383	ADP
fnp-3528	438	10	taking	take	VERB
fnp-3528	438	11	the	the	DET
fnp-3528	438	12	challenge	challenge	NOUN
fnp-3528	438	13	of	of	ADP
fnp-3528	438	14	cns	cns	NOUN
fnp-3528	438	15	penetration	penetration	NOUN
fnp-3528	438	16	of	of	ADP
fnp-3528	438	17	these	these	DET
fnp-3528	438	18	drugs	drug	NOUN
fnp-3528	438	19	into	into	ADP
fnp-3528	438	20	account	account	NOUN
fnp-3528	438	21	,	,	PUNCT
fnp-3528	438	22	drugs	drug	NOUN
fnp-3528	438	23	active	active	ADJ
fnp-3528	438	24	in	in	ADP
fnp-3528	438	25	atherosclerosis	atherosclerosis	NOUN
fnp-3528	438	26	models	model	NOUN
fnp-3528	438	27	could	could	AUX
fnp-3528	438	28	generally	generally	ADV
fnp-3528	438	29	be	be	AUX
fnp-3528	438	30	suggested	suggest	VERB
fnp-3528	438	31	to	to	PART
fnp-3528	438	32	also	also	ADV
fnp-3528	438	33	have	have	VERB
fnp-3528	438	34	certain	certain	ADJ
fnp-3528	438	35	therapeutic	therapeutic	ADJ
fnp-3528	438	36	relevance	relevance	NOUN
fnp-3528	438	37	regarding	regard	VERB
fnp-3528	438	38	ad	ad	NOUN
fnp-3528	438	39	.	.	PUNCT
fnp-3528	439	1	nevertheless	nevertheless	ADV
fnp-3528	439	2	,	,	PUNCT
fnp-3528	439	3	so	so	ADV
fnp-3528	439	4	far	far	ADV
fnp-3528	439	5	,	,	PUNCT
fnp-3528	439	6	none	none	NOUN
fnp-3528	439	7	of	of	ADP
fnp-3528	439	8	these	these	DET
fnp-3528	439	9	drugs	drug	NOUN
fnp-3528	439	10	has	have	AUX
fnp-3528	439	11	made	make	VERB
fnp-3528	439	12	it	it	PRON
fnp-3528	439	13	into	into	ADP
fnp-3528	439	14	clinical	clinical	ADJ
fnp-3528	439	15	evaluation	evaluation	NOUN
fnp-3528	439	16	in	in	ADP
fnp-3528	439	17	humans	human	NOUN
fnp-3528	439	18	.	.	PUNCT
fnp-3528	440	1	the	the	DET
fnp-3528	440	2	underlying	underlie	VERB
fnp-3528	440	3	cause	cause	NOUN
fnp-3528	440	4	can	can	AUX
fnp-3528	440	5	be	be	AUX
fnp-3528	440	6	pinned	pin	VERB
fnp-3528	440	7	to	to	ADP
fnp-3528	440	8	the	the	DET
fnp-3528	440	9	fact	fact	NOUN
fnp-3528	440	10	that	that	SCONJ
fnp-3528	440	11	the	the	DET
fnp-3528	440	12	principal	principal	ADJ
fnp-3528	440	13	mechanism	mechanism	NOUN
fnp-3528	440	14	by	by	ADP
fnp-3528	440	15	which	which	PRON
fnp-3528	440	16	abca	abca	NOUN
fnp-3528	440	17	transporters	transporter	NOUN
fnp-3528	440	18	contribute	contribute	VERB
fnp-3528	440	19	to	to	ADP
fnp-3528	440	20	ad	ad	NOUN
fnp-3528	440	21	is	be	AUX
fnp-3528	440	22	still	still	ADV
fnp-3528	440	23	unknown	unknown	ADJ
fnp-3528	440	24	.	.	PUNCT
fnp-3528	441	1	while	while	SCONJ
fnp-3528	441	2	a	a	DET
fnp-3528	441	3	rationale	rationale	NOUN
fnp-3528	441	4	can	can	AUX
fnp-3528	441	5	be	be	AUX
fnp-3528	441	6	found	find	VERB
fnp-3528	441	7	in	in	ADP
fnp-3528	441	8	atherosclerosis	atherosclerosis	NOUN
fnp-3528	441	9	(	(	PUNCT
fnp-3528	441	10	efflux	efflux	NOUN
fnp-3528	441	11	of	of	ADP
fnp-3528	441	12	cellular	cellular	ADJ
fnp-3528	441	13	lipid	lipid	NOUN
fnp-3528	441	14	to	to	ADP
fnp-3528	441	15	apoe	apoe	VERB
fnp-3528	441	16	and	and	CCONJ
fnp-3528	441	17	hdl	hdl	PROPN
fnp-3528	441	18	resulting	result	VERB
fnp-3528	441	19	in	in	ADP
fnp-3528	441	20	lower	low	ADJ
fnp-3528	441	21	lipid	lipid	NOUN
fnp-3528	441	22	burden	burden	NOUN
fnp-3528	441	23	in	in	ADP
fnp-3528	441	24	the	the	DET
fnp-3528	441	25	vascular	vascular	ADJ
fnp-3528	441	26	system	system	NOUN
fnp-3528	441	27	)	)	PUNCT
fnp-3528	441	28	,	,	PUNCT
fnp-3528	441	29	the	the	DET
fnp-3528	441	30	translation	translation	NOUN
fnp-3528	441	31	of	of	ADP
fnp-3528	441	32	this	this	DET
fnp-3528	441	33	rationale	rationale	NOUN
fnp-3528	441	34	to	to	ADP
fnp-3528	441	35	ad	ad	NOUN
fnp-3528	441	36	can	can	AUX
fnp-3528	441	37	only	only	ADV
fnp-3528	441	38	be	be	AUX
fnp-3528	441	39	achieved	achieve	VERB
fnp-3528	441	40	to	to	ADP
fnp-3528	441	41	a	a	DET
fnp-3528	441	42	very	very	ADV
fnp-3528	441	43	limited	limited	ADJ
fnp-3528	441	44	extent	extent	NOUN
fnp-3528	441	45	.	.	PUNCT
fnp-3528	442	1	several	several	ADJ
fnp-3528	442	2	questions	question	NOUN
fnp-3528	442	3	need	need	VERB
fnp-3528	442	4	addressing	address	VERB
fnp-3528	442	5	in	in	ADP
fnp-3528	442	6	future	future	ADJ
fnp-3528	442	7	evaluations	evaluation	NOUN
fnp-3528	442	8	:	:	PUNCT
fnp-3528	442	9	(	(	PUNCT
fnp-3528	442	10	i	i	NOUN
fnp-3528	442	11	)	)	PUNCT
fnp-3528	442	12	what	what	PRON
fnp-3528	442	13	is	be	AUX
fnp-3528	442	14	the	the	DET
fnp-3528	442	15	general	general	ADJ
fnp-3528	442	16	function	function	NOUN
fnp-3528	442	17	of	of	ADP
fnp-3528	442	18	abca	abca	NOUN
fnp-3528	442	19	transporters	transporter	NOUN
fnp-3528	442	20	in	in	ADP
fnp-3528	442	21	the	the	DET
fnp-3528	442	22	brain	brain	NOUN
fnp-3528	442	23	to	to	PART
fnp-3528	442	24	ameliorate	ameliorate	VERB
fnp-3528	442	25	(	(	PUNCT
fnp-3528	442	26	or	or	CCONJ
fnp-3528	442	27	exacerbate	exacerbate	VERB
fnp-3528	442	28	)	)	PUNCT
fnp-3528	442	29	ad	ad	NOUN
fnp-3528	442	30	in	in	ADP
fnp-3528	442	31	patients	patient	NOUN
fnp-3528	442	32	;	;	PUNCT
fnp-3528	442	33	(	(	PUNCT
fnp-3528	442	34	ii	ii	NOUN
fnp-3528	442	35	)	)	PUNCT
fnp-3528	442	36	when	when	SCONJ
fnp-3528	442	37	does	do	AUX
fnp-3528	442	38	this	this	DET
fnp-3528	442	39	development	development	NOUN
fnp-3528	442	40	start	start	VERB
fnp-3528	442	41	;	;	PUNCT
fnp-3528	442	42	and	and	CCONJ
fnp-3528	442	43	(	(	PUNCT
fnp-3528	442	44	iii	iii	NOUN
fnp-3528	442	45	)	)	PUNCT
fnp-3528	442	46	at	at	ADP
fnp-3528	442	47	which	which	DET
fnp-3528	442	48	stage	stage	NOUN
fnp-3528	442	49	of	of	ADP
fnp-3528	442	50	development	development	NOUN
fnp-3528	442	51	can	can	AUX
fnp-3528	442	52	a	a	DET
fnp-3528	442	53	pharmacological	pharmacological	ADJ
fnp-3528	442	54	intervention	intervention	NOUN
fnp-3528	442	55	with	with	SCONJ
fnp-3528	442	56	abca	abca	NOUN
fnp-3528	442	57	transporter	transporter	NOUN
fnp-3528	442	58	modulators	modulator	NOUN
fnp-3528	442	59	lead	lead	VERB
fnp-3528	442	60	to	to	ADP
fnp-3528	442	61	a	a	DET
fnp-3528	442	62	positive	positive	ADJ
fnp-3528	442	63	therapeutic	therapeutic	ADJ
fnp-3528	442	64	effect	effect	NOUN
fnp-3528	442	65	?	?	PUNCT
fnp-3528	443	1	in	in	ADP
fnp-3528	443	2	this	this	DET
fnp-3528	443	3	regard	regard	NOUN
fnp-3528	443	4	,	,	PUNCT
fnp-3528	443	5	more	more	ADV
fnp-3528	443	6	in	in	ADP
fnp-3528	443	7	vitro	vitro	X
fnp-3528	443	8	tests	test	NOUN
fnp-3528	443	9	are	be	AUX
fnp-3528	443	10	needed	need	VERB
fnp-3528	443	11	with	with	ADP
fnp-3528	443	12	new	new	ADJ
fnp-3528	443	13	lead	lead	NOUN
fnp-3528	443	14	structures	structure	NOUN
fnp-3528	443	15	that	that	PRON
fnp-3528	443	16	are	be	AUX
fnp-3528	443	17	rigorously	rigorously	ADV
fnp-3528	443	18	assessed	assess	VERB
fnp-3528	443	19	for	for	ADP
fnp-3528	443	20	their	their	PRON
fnp-3528	443	21	particular	particular	ADJ
fnp-3528	443	22	mechanism	mechanism	NOUN
fnp-3528	443	23	of	of	ADP
fnp-3528	443	24	action	action	NOUN
fnp-3528	443	25	–	–	PUNCT
fnp-3528	443	26	to	to	PART
fnp-3528	443	27	study	study	VERB
fnp-3528	443	28	vice	vice	NOUN
fnp-3528	443	29	versa	versa	VERB
fnp-3528	443	30	the	the	DET
fnp-3528	443	31	mechanism	mechanism	NOUN
fnp-3528	443	32	of	of	ADP
fnp-3528	443	33	action	action	NOUN
fnp-3528	443	34	of	of	ADP
fnp-3528	443	35	abca	abca	PROPN
fnp-3528	443	36	transporters	transporter	NOUN
fnp-3528	443	37	in	in	ADP
fnp-3528	443	38	general	general	ADJ
fnp-3528	443	39	.	.	PUNCT
fnp-3528	444	1	one	one	NUM
fnp-3528	444	2	possibility	possibility	NOUN
fnp-3528	444	3	to	to	PART
fnp-3528	444	4	gain	gain	VERB
fnp-3528	444	5	novel	novel	ADJ
fnp-3528	444	6	lead	lead	NOUN
fnp-3528	444	7	structures	structure	NOUN
fnp-3528	444	8	is	be	AUX
fnp-3528	444	9	the	the	DET
fnp-3528	444	10	screening	screening	NOUN
fnp-3528	444	11	of	of	ADP
fnp-3528	444	12	huge	huge	ADJ
fnp-3528	444	13	analog	analog	NOUN
fnp-3528	444	14	compound	compound	NOUN
fnp-3528	444	15	libraries	library	NOUN
fnp-3528	444	16	.	.	PUNCT
fnp-3528	445	1	however	however	ADV
fnp-3528	445	2	,	,	PUNCT
fnp-3528	445	3	the	the	DET
fnp-3528	445	4	number	number	NOUN
fnp-3528	445	5	of	of	ADP
fnp-3528	445	6	existing	exist	VERB
fnp-3528	445	7	compounds	compound	NOUN
fnp-3528	445	8	is	be	AUX
fnp-3528	445	9	limited	limit	VERB
fnp-3528	445	10	,	,	PUNCT
fnp-3528	445	11	and	and	CCONJ
fnp-3528	445	12	blind	blind	ADJ
fnp-3528	445	13	in	in	ADP
fnp-3528	445	14	vitro	vitro	X
fnp-3528	445	15	testing	testing	NOUN
fnp-3528	445	16	is	be	AUX
fnp-3528	445	17	resource	resource	NOUN
fnp-3528	445	18	-	-	PUNCT
fnp-3528	445	19	consuming	consume	VERB
fnp-3528	445	20	,	,	PUNCT
fnp-3528	445	21	especially	especially	ADV
fnp-3528	445	22	regarding	regard	VERB
fnp-3528	445	23	time	time	NOUN
fnp-3528	445	24	and	and	CCONJ
fnp-3528	445	25	funds	fund	NOUN
fnp-3528	445	26	.	.	PUNCT
fnp-3528	446	1	computational	computational	ADJ
fnp-3528	446	2	methodologies	methodology	NOUN
fnp-3528	446	3	may	may	AUX
fnp-3528	446	4	help	help	VERB
fnp-3528	446	5	to	to	PART
fnp-3528	446	6	generate	generate	VERB
fnp-3528	446	7	novel	novel	ADJ
fnp-3528	446	8	lead	lead	NOUN
fnp-3528	446	9	structures	structure	NOUN
fnp-3528	446	10	based	base	VERB
fnp-3528	446	11	on	on	ADP
fnp-3528	446	12	the	the	DET
fnp-3528	446	13	knowledge	knowledge	NOUN
fnp-3528	446	14	of	of	ADP
fnp-3528	446	15	existing	exist	VERB
fnp-3528	446	16	modulators	modulator	NOUN
fnp-3528	446	17	of	of	ADP
fnp-3528	446	18	abca	abca	NOUN
fnp-3528	446	19	transporters	transporter	NOUN
fnp-3528	446	20	.	.	PUNCT
fnp-3528	447	1	this	this	PRON
fnp-3528	447	2	has	have	AUX
fnp-3528	447	3	led	lead	VERB
fnp-3528	447	4	to	to	ADP
fnp-3528	447	5	new	new	ADJ
fnp-3528	447	6	lead	lead	NOUN
fnp-3528	447	7	molecules	molecule	NOUN
fnp-3528	447	8	in	in	ADP
fnp-3528	447	9	the	the	DET
fnp-3528	447	10	past.18,19,493,495	past.18,19,493,495	ADJ
fnp-3528	447	11	particularly	particularly	ADV
fnp-3528	447	12	the	the	DET
fnp-3528	447	13	knowledge	knowledge	NOUN
fnp-3528	447	14	on	on	ADP
fnp-3528	447	15	abca1	abca1	NOUN
fnp-3528	447	16	and	and	CCONJ
fnp-3528	447	17	abca8	abca8	NOUN
fnp-3528	447	18	inhibitors	inhibitor	NOUN
fnp-3528	447	19	and	and	CCONJ
fnp-3528	447	20	substrates	substrate	NOUN
fnp-3528	447	21	is	be	AUX
fnp-3528	447	22	of	of	ADP
fnp-3528	447	23	interest	interest	NOUN
fnp-3528	447	24	,	,	PUNCT
fnp-3528	447	25	because	because	SCONJ
fnp-3528	447	26	these	these	DET
fnp-3528	447	27	compounds	compound	NOUN
fnp-3528	447	28	inherit	inherit	VERB
fnp-3528	447	29	the	the	DET
fnp-3528	447	30	molecular	molecular	ADJ
fnp-3528	447	31	-	-	PUNCT
fnp-3528	447	32	structural	structural	ADJ
fnp-3528	447	33	information	information	NOUN
fnp-3528	447	34	that	that	PRON
fnp-3528	447	35	is	be	AUX
fnp-3528	447	36	critical	critical	ADJ
fnp-3528	447	37	for	for	ADP
fnp-3528	447	38	direct	direct	ADJ
fnp-3528	447	39	binding	binding	NOUN
fnp-3528	447	40	to	to	ADP
fnp-3528	447	41	these	these	DET
fnp-3528	447	42	transporters	transporter	NOUN
fnp-3528	447	43	.	.	PUNCT
fnp-3528	448	1	considering	consider	VERB
fnp-3528	448	2	the	the	DET
fnp-3528	448	3	newly	newly	ADV
fnp-3528	448	4	developed	develop	VERB
fnp-3528	448	5	pattern	pattern	NOUN
fnp-3528	448	6	analysis	analysis	NOUN
fnp-3528	448	7	methodology	methodology	NOUN
fnp-3528	448	8	,	,	PUNCT
fnp-3528	448	9	c@pa,18,19,495	c@pa,18,19,495	PROPN
fnp-3528	448	10	the	the	DET
fnp-3528	448	11	scaffolds	scaffold	NOUN
fnp-3528	448	12	and	and	CCONJ
fnp-3528	448	13	substructural	substructural	ADJ
fnp-3528	448	14	composition	composition	NOUN
fnp-3528	448	15	of	of	ADP
fnp-3528	448	16	this	this	DET
fnp-3528	448	17	set	set	NOUN
fnp-3528	448	18	of	of	ADP
fnp-3528	448	19	molecules	molecule	NOUN
fnp-3528	448	20	may	may	AUX
fnp-3528	448	21	reveal	reveal	VERB
fnp-3528	448	22	the	the	DET
fnp-3528	448	23	critical	critical	ADJ
fnp-3528	448	24	necessities	necessity	NOUN
fnp-3528	448	25	for	for	ADP
fnp-3528	448	26	direct	direct	ADJ
fnp-3528	448	27	interaction	interaction	NOUN
fnp-3528	448	28	with	with	ADP
fnp-3528	448	29	abca	abca	PROPN
fnp-3528	448	30	transporters	transporter	NOUN
fnp-3528	448	31	.	.	PUNCT
fnp-3528	449	1	c@pa	c@pa	NOUN
fnp-3528	449	2	is	be	AUX
fnp-3528	449	3	therefore	therefore	ADV
fnp-3528	449	4	of	of	ADP
fnp-3528	449	5	high	high	ADJ
fnp-3528	449	6	relevance	relevance	NOUN
fnp-3528	449	7	because	because	SCONJ
fnp-3528	449	8	it	it	PRON
fnp-3528	449	9	was	be	AUX
fnp-3528	449	10	specifically	specifically	ADV
fnp-3528	449	11	developed	develop	VERB
fnp-3528	449	12	to	to	PART
fnp-3528	449	13	gain	gain	VERB
fnp-3528	449	14	multitargeting	multitargete	VERB
fnp-3528	449	15	pan	pan	ADJ
fnp-3528	449	16	-	-	ADJ
fnp-3528	449	17	abc	abc	ADJ
fnp-3528	449	18	transporter	transporter	NOUN
fnp-3528	449	19	modulators18,19,495	modulators18,19,495	ADJ
fnp-3528	449	20	–	–	PUNCT
fnp-3528	449	21	molecules	molecule	NOUN
fnp-3528	449	22	that	that	PRON
fnp-3528	449	23	particularly	particularly	ADV
fnp-3528	449	24	interact	interact	VERB
fnp-3528	449	25	with	with	ADP
fnp-3528	449	26	different	different	ADJ
fnp-3528	449	27	abc	abc	PROPN
fnp-3528	449	28	transporters	transporter	NOUN
fnp-3528	449	29	of	of	ADP
fnp-3528	449	30	different	different	ADJ
fnp-3528	449	31	subfamilies	subfamily	NOUN
fnp-3528	449	32	.	.	PUNCT
fnp-3528	450	1	assuming	assume	VERB
fnp-3528	450	2	that	that	SCONJ
fnp-3528	450	3	a	a	DET
fnp-3528	450	4	conserved	conserve	VERB
fnp-3528	450	5	multitarget	multitarget	NOUN
fnp-3528	450	6	binding	bind	VERB
fnp-3528	450	7	site	site	NOUN
fnp-3528	450	8	exists	exist	VERB
fnp-3528	450	9	as	as	SCONJ
fnp-3528	450	10	proposed	propose	VERB
fnp-3528	450	11	earlier,6,14,475	earlier,6,14,475	PROPN
fnp-3528	450	12	multitargeting	multitargeting	NOUN
fnp-3528	450	13	may	may	AUX
fnp-3528	450	14	be	be	AUX
fnp-3528	450	15	the	the	DET
fnp-3528	450	16	key	key	NOUN
fnp-3528	450	17	to	to	PART
fnp-3528	450	18	explore	explore	VERB
fnp-3528	450	19	under	under	ADP
fnp-3528	450	20	-	-	PUNCT
fnp-3528	450	21	studied	study	VERB
fnp-3528	450	22	abc	abc	PROPN
fnp-3528	450	23	transporters	transporter	NOUN
fnp-3528	450	24	in	in	ADP
fnp-3528	450	25	general	general	ADJ
fnp-3528	450	26	and	and	CCONJ
fnp-3528	450	27	abca	abca	PROPN
fnp-3528	450	28	transporters	transporter	NOUN
fnp-3528	450	29	in	in	ADP
fnp-3528	450	30	particular.6,14,18,19	particular.6,14,18,19	PROPN
fnp-3528	450	31	several	several	ADJ
fnp-3528	450	32	thousands	thousand	NOUN
fnp-3528	450	33	of	of	ADP
fnp-3528	450	34	these	these	DET
fnp-3528	450	35	molecules	molecule	NOUN
fnp-3528	450	36	have	have	AUX
fnp-3528	450	37	already	already	ADV
fnp-3528	450	38	been	be	AUX
fnp-3528	450	39	predicted,18,19,493,495	predicted,18,19,493,495	ADJ
fnp-3528	450	40	and	and	CCONJ
fnp-3528	450	41	the	the	DET
fnp-3528	450	42	predictions	prediction	NOUN
fnp-3528	450	43	were	be	AUX
fnp-3528	450	44	in	in	ADP
fnp-3528	450	45	part	part	NOUN
fnp-3528	450	46	biologically	biologically	ADV
fnp-3528	450	47	confirmed.18,19,493,495	confirmed.18,19,493,495	X
fnp-3528	450	48	additionally	additionally	ADV
fnp-3528	450	49	,	,	PUNCT
fnp-3528	450	50	selected	select	VERB
fnp-3528	450	51	pan	pan	PROPN
fnp-3528	450	52	-	-	ADJ
fnp-3528	450	53	abc	abc	ADJ
fnp-3528	450	54	transporter	transporter	NOUN
fnp-3528	450	55	inhibitors	inhibitor	NOUN
fnp-3528	450	56	were	be	AUX
fnp-3528	450	57	analyzed	analyze	VERB
fnp-3528	450	58	in	in	ADP
fnp-3528	450	59	molecular	molecular	ADJ
fnp-3528	450	60	docking	docking	NOUN
fnp-3528	450	61	studies	study	NOUN
fnp-3528	450	62	,	,	PUNCT
fnp-3528	450	63	which	which	PRON
fnp-3528	450	64	revealed	reveal	VERB
fnp-3528	450	65	the	the	DET
fnp-3528	450	66	potential	potential	ADJ
fnp-3528	450	67	existence	existence	NOUN
fnp-3528	450	68	of	of	ADP
fnp-3528	450	69	the	the	DET
fnp-3528	450	70	multitarget	multitarget	PROPN
fnp-3528	450	71	binding	bind	VERB
fnp-3528	450	72	site.475	site.475	PROPN
fnp-3528	450	73	hence	hence	ADV
fnp-3528	450	74	,	,	PUNCT
fnp-3528	450	75	combining	combine	VERB
fnp-3528	450	76	the	the	DET
fnp-3528	450	77	existent	existent	ADJ
fnp-3528	450	78	knowledge	knowledge	NOUN
fnp-3528	450	79	of	of	ADP
fnp-3528	450	80	abca	abca	NOUN
fnp-3528	450	81	transporter	transporter	NOUN
fnp-3528	450	82	modulators	modulator	NOUN
fnp-3528	450	83	with	with	ADP
fnp-3528	450	84	(	(	PUNCT
fnp-3528	450	85	sub)structural	sub)structural	ADJ
fnp-3528	450	86	elements	element	NOUN
fnp-3528	450	87	of	of	ADP
fnp-3528	450	88	these	these	DET
fnp-3528	450	89	pan	pan	NOUN
fnp-3528	450	90	-	-	ADJ
fnp-3528	450	91	abc	abc	ADJ
fnp-3528	450	92	transporter	transporter	NOUN
fnp-3528	450	93	modulators	modulator	NOUN
fnp-3528	450	94	and	and	CCONJ
fnp-3528	450	95	powerful	powerful	ADJ
fnp-3528	450	96	computational	computational	ADJ
fnp-3528	450	97	approaches	approach	NOUN
fnp-3528	450	98	(	(	PUNCT
fnp-3528	450	99	e.g.	e.g.	ADV
fnp-3528	450	100	,	,	PUNCT
fnp-3528	450	101	molecular	molecular	ADJ
fnp-3528	450	102	docking	docking	NOUN
fnp-3528	450	103	or	or	CCONJ
fnp-3528	450	104	molecular	molecular	ADJ
fnp-3528	450	105	dynamics	dynamic	NOUN
fnp-3528	450	106	simulations	simulation	NOUN
fnp-3528	450	107	)	)	PUNCT
fnp-3528	450	108	could	could	AUX
fnp-3528	450	109	ultimately	ultimately	ADV
fnp-3528	450	110	lead	lead	VERB
fnp-3528	450	111	to	to	ADP
fnp-3528	450	112	the	the	DET
fnp-3528	450	113	successful	successful	ADJ
fnp-3528	450	114	exploration	exploration	NOUN
fnp-3528	450	115	of	of	ADP
fnp-3528	450	116	abca	abca	NOUN
fnp-3528	450	117	transporters	transporter	NOUN
fnp-3528	450	118	in	in	ADP
fnp-3528	450	119	general	general	ADJ
fnp-3528	450	120	,	,	PUNCT
fnp-3528	450	121	as	as	ADV
fnp-3528	450	122	well	well	ADV
fnp-3528	450	123	as	as	ADP
fnp-3528	450	124	abca1	abca1	NOUN
fnp-3528	450	125	and	and	CCONJ
fnp-3528	450	126	abca7	abca7	NOUN
fnp-3528	450	127	in	in	ADP
fnp-3528	450	128	particular.28,95,103	particular.28,95,103	NOUN
fnp-3528	450	129	-	-	ADJ
fnp-3528	450	130	112	112	NUM
fnp-3528	450	131	several	several	ADJ
fnp-3528	450	132	drugs	drug	NOUN
fnp-3528	450	133	and	and	CCONJ
fnp-3528	450	134	drug	drug	NOUN
fnp-3528	450	135	-	-	PUNCT
fnp-3528	450	136	like	like	ADJ
fnp-3528	450	137	compounds	compound	NOUN
fnp-3528	450	138	have	have	AUX
fnp-3528	450	139	already	already	ADV
fnp-3528	450	140	been	be	AUX
fnp-3528	450	141	demonstrated	demonstrate	VERB
fnp-3528	450	142	to	to	PART
fnp-3528	450	143	be	be	AUX
fnp-3528	450	144	pan	pan	ADJ
fnp-3528	450	145	-	-	ADJ
fnp-3528	450	146	abc	abc	ADJ
fnp-3528	450	147	transporter	transporter	NOUN
fnp-3528	450	148	modulators	modulator	NOUN
fnp-3528	450	149	interacting	interact	VERB
fnp-3528	450	150	also	also	ADV
fnp-3528	450	151	with	with	ADP
fnp-3528	450	152	abca	abca	PROPN
fnp-3528	450	153	transporters	transporter	NOUN
fnp-3528	450	154	.	.	PUNCT
fnp-3528	451	1	these	these	DET
fnp-3528	451	2	drugs	drug	NOUN
fnp-3528	451	3	and	and	CCONJ
fnp-3528	451	4	drug	drug	NOUN
fnp-3528	451	5	-	-	PUNCT
fnp-3528	451	6	like	like	ADJ
fnp-3528	451	7	compounds	compound	NOUN
fnp-3528	451	8	are	be	AUX
fnp-3528	451	9	,	,	PUNCT
fnp-3528	451	10	for	for	ADP
fnp-3528	451	11	example	example	NOUN
fnp-3528	451	12	,	,	PUNCT
fnp-3528	451	13	cyclosporine	cyclosporine	VERB
fnp-3528	451	14	a	a	DET
fnp-3528	451	15	(	(	PUNCT
fnp-3528	451	16	9	9	NUM
fnp-3528	451	17	targets	target	NOUN
fnp-3528	451	18	of	of	ADP
fnp-3528	451	19	4	4	NUM
fnp-3528	451	20	subfamilies	subfamily	NOUN
fnp-3528	451	21	:	:	PUNCT
fnp-3528	452	1	abca1,245	abca1,245	PROPN
fnp-3528	452	2	abcb1,20	abcb1,20	VERB
fnp-3528	452	3	abcb4,552	abcb4,552	PROPN
fnp-3528	453	1	abcb11,553	abcb11,553	ADP
fnp-3528	453	2	abcc1–2,24,554	abcc1–2,24,554	PROPN
fnp-3528	453	3	abcc10,26	abcc10,26	NOUN
fnp-3528	453	4	and	and	CCONJ
fnp-3528	453	5	abcg1–2555,556	abcg1–2555,556	NUM
fnp-3528	453	6	)	)	PUNCT
fnp-3528	453	7	,	,	PUNCT
fnp-3528	453	8	glibenclamide	glibenclamide	NOUN
fnp-3528	453	9	(	(	PUNCT
fnp-3528	453	10	8	8	NUM
fnp-3528	453	11	targets	target	NOUN
fnp-3528	453	12	of	of	ADP
fnp-3528	453	13	4	4	NUM
fnp-3528	453	14	subfamilies	subfamily	NOUN
fnp-3528	453	15	:	:	PUNCT
fnp-3528	453	16	abca1,270	abca1,270	X
fnp-3528	454	1	abcb11,553	abcb11,553	PROPN
fnp-3528	454	2	abcc1,24	abcc1,24	VERB
fnp-3528	454	3	abcc5,557	abcc5,557	X
fnp-3528	455	1	abcc7–9,558	abcc7–9,558	ADJ
fnp-3528	455	2	-	-	PUNCT
fnp-3528	455	3	560	560	NUM
fnp-3528	455	4	and	and	CCONJ
fnp-3528	455	5	abcg2554	abcg2554	PROPN
fnp-3528	455	6	)	)	PUNCT
fnp-3528	456	1	,	,	PUNCT
fnp-3528	456	2	imatinib	imatinib	NOUN
fnp-3528	456	3	(	(	PUNCT
fnp-3528	456	4	6	6	NUM
fnp-3528	456	5	targets	target	NOUN
fnp-3528	456	6	of	of	ADP
fnp-3528	456	7	4	4	NUM
fnp-3528	456	8	subfamilies	subfamily	NOUN
fnp-3528	456	9	:	:	PUNCT
fnp-3528	456	10	abca3,426	abca3,426	NOUN
fnp-3528	456	11	abcb1,561	abcb1,561	PROPN
fnp-3528	457	1	abcb11,553	abcb11,553	PROPN
fnp-3528	457	2	abcc1,561	abcc1,561	PROPN
fnp-3528	457	3	abcc10,561	abcc10,561	PROPN
fnp-3528	457	4	and	and	CCONJ
fnp-3528	457	5	abcg2561	abcg2561	PROPN
fnp-3528	457	6	)	)	PUNCT
fnp-3528	457	7	,	,	PUNCT
fnp-3528	457	8	probenecid	probenecid	PROPN
fnp-3528	457	9	(	(	PUNCT
fnp-3528	457	10	8	8	NUM
fnp-3528	457	11	targets	target	NOUN
fnp-3528	457	12	of	of	ADP
fnp-3528	457	13	2	2	NUM
fnp-3528	457	14	subfamilies	subfamily	NOUN
fnp-3528	457	15	:	:	PUNCT
fnp-3528	457	16	abca8,222	abca8,222	ADJ
fnp-3528	457	17	abcc1–6,24,26,562	abcc1–6,24,26,562	NOUN
fnp-3528	457	18	-	-	PUNCT
fnp-3528	457	19	564	564	NUM
fnp-3528	457	20	abcc10565	abcc10565	NOUN
fnp-3528	457	21	)	)	PUNCT
fnp-3528	457	22	,	,	PUNCT
fnp-3528	457	23	verapamil	verapamil	NOUN
fnp-3528	457	24	(	(	PUNCT
fnp-3528	457	25	9	9	NUM
fnp-3528	457	26	targets	target	NOUN
fnp-3528	457	27	of	of	ADP
fnp-3528	457	28	4	4	NUM
fnp-3528	457	29	subfamilies	subfamily	NOUN
fnp-3528	457	30	:	:	PUNCT
fnp-3528	457	31	abca8,222	abca8,222	PROPN
fnp-3528	457	32	abcb1,20	abcb1,20	VERB
fnp-3528	458	1	abcb4–5,552,566	abcb4–5,552,566	PROPN
fnp-3528	458	2	abcb11,567	abcb11,567	PROPN
fnp-3528	458	3	abcc1,24	abcc1,24	VERB
fnp-3528	458	4	abcc4,568	abcc4,568	NOUN
fnp-3528	458	5	abcc10,565	abcc10,565	PROPN
fnp-3528	458	6	and	and	CCONJ
fnp-3528	458	7	abcg2554	abcg2554	PROPN
fnp-3528	458	8	)	)	PUNCT
fnp-3528	458	9	,	,	PUNCT
fnp-3528	458	10	and	and	CCONJ
fnp-3528	458	11	verlukast	verlukast	VERB
fnp-3528	458	12	(	(	PUNCT
fnp-3528	458	13	11	11	NUM
fnp-3528	458	14	targets	target	NOUN
fnp-3528	458	15	of	of	ADP
fnp-3528	458	16	4	4	NUM
fnp-3528	458	17	subfamilies	subfamily	NOUN
fnp-3528	458	18	:	:	PUNCT
fnp-3528	458	19	abca8,222	abca8,222	X
fnp-3528	458	20	abcb4,552	abcb4,552	NOUN
fnp-3528	458	21	abcb11,553	abcb11,553	PROPN
fnp-3528	458	22	abcc1–5,24,554,557,564,569	abcc1–5,24,554,557,564,569	NOUN
fnp-3528	458	23	abcc10–11,26,570	abcc10–11,26,570	PROPN
fnp-3528	458	24	abcg2554	abcg2554	PROPN
fnp-3528	458	25	)	)	PUNCT
fnp-3528	458	26	.	.	PUNCT
fnp-3528	459	1	in	in	ADP
fnp-3528	459	2	silico	silico	NOUN
fnp-3528	459	3	analyses	analysis	NOUN
fnp-3528	459	4	with	with	ADP
fnp-3528	459	5	verapamil	verapamil	NOUN
fnp-3528	459	6	and	and	CCONJ
fnp-3528	459	7	verlukast	verlukast	VERB
fnp-3528	459	8	supported	support	VERB
fnp-3528	459	9	the	the	DET
fnp-3528	459	10	notion	notion	NOUN
fnp-3528	459	11	of	of	ADP
fnp-3528	459	12	addressing	address	VERB
fnp-3528	459	13	the	the	DET
fnp-3528	459	14	multitarget	multitarget	NOUN
fnp-3528	459	15	binding	bind	VERB
fnp-3528	459	16	site	site	NOUN
fnp-3528	459	17	in	in	ADP
fnp-3528	459	18	abca7.475	abca7.475	PROPN
fnp-3528	459	19	taking	take	VERB
fnp-3528	459	20	their	their	PRON
fnp-3528	459	21	structural	structural	ADJ
fnp-3528	459	22	peculiarities	peculiarity	NOUN
fnp-3528	459	23	in	in	ADP
fnp-3528	459	24	a	a	DET
fnp-3528	459	25	pattern	pattern	NOUN
fnp-3528	459	26	-	-	PUNCT
fnp-3528	459	27	based	base	VERB
fnp-3528	459	28	rational	rational	ADJ
fnp-3528	459	29	drug	drug	NOUN
fnp-3528	459	30	design	design	NOUN
fnp-3528	459	31	approach	approach	NOUN
fnp-3528	459	32	into	into	ADP
fnp-3528	459	33	account	account	NOUN
fnp-3528	459	34	may	may	AUX
fnp-3528	459	35	yield	yield	VERB
fnp-3528	459	36	novel	novel	ADJ
fnp-3528	459	37	lead	lead	NOUN
fnp-3528	459	38	structures	structure	NOUN
fnp-3528	459	39	for	for	ADP
fnp-3528	459	40	functional	functional	ADJ
fnp-3528	459	41	in	in	ADP
fnp-3528	459	42	vitro	vitro	X
fnp-3528	459	43	studies	study	NOUN
fnp-3528	459	44	of	of	ADP
fnp-3528	459	45	abca	abca	PROPN
fnp-3528	459	46	transporters	transporter	NOUN
fnp-3528	459	47	.	.	PUNCT
fnp-3528	460	1	this	this	PRON
fnp-3528	460	2	may	may	AUX
fnp-3528	460	3	ultimately	ultimately	ADV
fnp-3528	460	4	result	result	VERB
fnp-3528	460	5	in	in	ADP
fnp-3528	460	6	the	the	DET
fnp-3528	460	7	development	development	NOUN
fnp-3528	460	8	of	of	ADP
fnp-3528	460	9	innovative	innovative	ADJ
fnp-3528	460	10	ad	ad	NOUN
fnp-3528	460	11	diagnostics	diagnostic	NOUN
fnp-3528	460	12	and	and	CCONJ
fnp-3528	460	13	therapeutics	therapeutic	NOUN
fnp-3528	460	14	.	.	PUNCT
fnp-3528	461	1	appendix	appendix	ADJ
fnp-3528	461	2	author	author	NOUN
fnp-3528	461	3	information	information	NOUN
fnp-3528	461	4	corresponding	correspond	VERB
fnp-3528	461	5	author	author	NOUN
fnp-3528	461	6	sven	sven	PROPN
fnp-3528	461	7	marcel	marcel	PROPN
fnp-3528	461	8	stefan	stefan	PROPN
fnp-3528	461	9	,	,	PUNCT
fnp-3528	461	10	department	department	PROPN
fnp-3528	461	11	of	of	ADP
fnp-3528	461	12	pathology	pathology	PROPN
fnp-3528	461	13	,	,	PUNCT
fnp-3528	461	14	section	section	NOUN
fnp-3528	461	15	of	of	ADP
fnp-3528	461	16	neuropathology	neuropathology	NOUN
fnp-3528	461	17	,	,	PUNCT
fnp-3528	461	18	translational	translational	ADJ
fnp-3528	461	19	neurodegeneration	neurodegeneration	NOUN
fnp-3528	461	20	research	research	NOUN
fnp-3528	461	21	and	and	CCONJ
fnp-3528	461	22	neuropathology	neuropathology	NOUN
fnp-3528	461	23	lab	lab	NOUN
fnp-3528	461	24	,	,	PUNCT
fnp-3528	461	25	university	university	NOUN
fnp-3528	461	26	of	of	ADP
fnp-3528	461	27	oslo	oslo	PROPN
fnp-3528	461	28	and	and	CCONJ
fnp-3528	461	29	oslo	oslo	PROPN
fnp-3528	461	30	university	university	PROPN
fnp-3528	461	31	hospital	hospital	NOUN
fnp-3528	461	32	,	,	PUNCT
fnp-3528	461	33	sognsvannsveien	sognsvannsveien	NOUN
fnp-3528	461	34	20	20	NUM
fnp-3528	461	35	,	,	PUNCT
fnp-3528	461	36	0372	0372	NUM
fnp-3528	461	37	oslo	oslo	PROPN
fnp-3528	461	38	,	,	PUNCT
fnp-3528	461	39	norway	norway	PROPN
fnp-3528	461	40	;	;	PUNCT
fnp-3528	461	41	orcid	orcid	NUM
fnp-3528	461	42	:	:	PUNCT
fnp-3528	461	43	0000	0000	NUM
fnp-3528	461	44	-	-	PUNCT
fnp-3528	461	45	0002	0002	NUM
fnp-3528	461	46	-	-	PUNCT
fnp-3528	461	47	2048	2048	NUM
fnp-3528	461	48	-	-	PUNCT
fnp-3528	461	49	8598	8598	NUM
fnp-3528	461	50	email	email	NOUN
fnp-3528	461	51	:	:	PUNCT
fnp-3528	461	52	s.m.stefan@medisin.uio.no	s.m.stefan@medisin.uio.no	VERB
fnp-3528	461	53	authors	author	NOUN
fnp-3528	461	54	jens	jens	PROPN
fnp-3528	461	55	pahnke	pahnke	PROPN
fnp-3528	461	56	,	,	PUNCT
fnp-3528	461	57	department	department	NOUN
fnp-3528	461	58	of	of	ADP
fnp-3528	461	59	pathology	pathology	PROPN
fnp-3528	461	60	,	,	PUNCT
fnp-3528	461	61	section	section	NOUN
fnp-3528	461	62	of	of	ADP
fnp-3528	461	63	neuropathology	neuropathology	NOUN
fnp-3528	461	64	,	,	PUNCT
fnp-3528	461	65	translational	translational	ADJ
fnp-3528	461	66	neurodegeneration	neurodegeneration	NOUN
fnp-3528	461	67	research	research	NOUN
fnp-3528	461	68	and	and	CCONJ
fnp-3528	461	69	neuropathology	neuropathology	NOUN
fnp-3528	461	70	lab	lab	NOUN
fnp-3528	461	71	,	,	PUNCT
fnp-3528	461	72	university	university	NOUN
fnp-3528	461	73	of	of	ADP
fnp-3528	461	74	oslo	oslo	PROPN
fnp-3528	461	75	and	and	CCONJ
fnp-3528	461	76	oslo	oslo	PROPN
fnp-3528	461	77	university	university	PROPN
fnp-3528	461	78	hospital	hospital	NOUN
fnp-3528	461	79	,	,	PUNCT
fnp-3528	461	80	sognsvannsveien	sognsvannsveien	NOUN
fnp-3528	461	81	20	20	NUM
fnp-3528	461	82	,	,	PUNCT
fnp-3528	461	83	0372	0372	NUM
fnp-3528	461	84	oslo	oslo	PROPN
fnp-3528	461	85	,	,	PUNCT
fnp-3528	461	86	norway	norway	PROPN
fnp-3528	461	87	;	;	PUNCT
fnp-3528	461	88	lied	lie	VERB
fnp-3528	461	89	,	,	PUNCT
fnp-3528	461	90	university	university	NOUN
fnp-3528	461	91	of	of	ADP
fnp-3528	461	92	lübeck	lübeck	PROPN
fnp-3528	461	93	,	,	PUNCT
fnp-3528	461	94	ratzeburger	ratzeburger	NOUN
fnp-3528	461	95	allee	allee	PROPN
fnp-3528	461	96	160	160	NUM
fnp-3528	461	97	,	,	PUNCT
fnp-3528	461	98	23538	23538	NUM
fnp-3528	461	99	lübeck	lübeck	PROPN
fnp-3528	461	100	,	,	PUNCT
fnp-3528	461	101	germany	germany	PROPN
fnp-3528	461	102	;	;	PUNCT
fnp-3528	461	103	department	department	NOUN
fnp-3528	461	104	of	of	ADP
fnp-3528	461	105	pharmacology	pharmacology	NOUN
fnp-3528	461	106	,	,	PUNCT
fnp-3528	461	107	faculty	faculty	NOUN
fnp-3528	461	108	of	of	ADP
fnp-3528	461	109	medicine	medicine	NOUN
fnp-3528	461	110	,	,	PUNCT
fnp-3528	461	111	university	university	NOUN
fnp-3528	461	112	of	of	ADP
fnp-3528	461	113	latvia	latvia	PROPN
fnp-3528	461	114	,	,	PUNCT
fnp-3528	461	115	jelgavas	jelgavas	PROPN
fnp-3528	461	116	iela	iela	PROPN
fnp-3528	461	117	1	1	NUM
fnp-3528	461	118	,	,	PUNCT
fnp-3528	461	119	1004	1004	NUM
fnp-3528	461	120	rīga	rīga	NOUN
fnp-3528	461	121	,	,	PUNCT
fnp-3528	461	122	latvia	latvia	PROPN
fnp-3528	461	123	;	;	PUNCT
fnp-3528	461	124	orcid	orcid	NUM
fnp-3528	461	125	:	:	PUNCT
fnp-3528	461	126	0000	0000	NUM
fnp-3528	461	127	-	-	PUNCT
fnp-3528	461	128	0001	0001	NUM
fnp-3528	461	129	-	-	PUNCT
fnp-3528	461	130	7355	7355	NUM
fnp-3528	461	131	-	-	PUNCT
fnp-3528	461	132	4213	4213	NUM
fnp-3528	461	133	pablo	pablo	NOUN
fnp-3528	461	134	bascuñana	bascuñana	PROPN
fnp-3528	461	135	,	,	PUNCT
fnp-3528	461	136	department	department	PROPN
fnp-3528	461	137	of	of	ADP
fnp-3528	461	138	pathology	pathology	PROPN
fnp-3528	461	139	,	,	PUNCT
fnp-3528	461	140	section	section	NOUN
fnp-3528	461	141	of	of	ADP
fnp-3528	461	142	neuropathology	neuropathology	NOUN
fnp-3528	461	143	,	,	PUNCT
fnp-3528	461	144	translational	translational	ADJ
fnp-3528	461	145	neurodegeneration	neurodegeneration	NOUN
fnp-3528	461	146	research	research	NOUN
fnp-3528	461	147	and	and	CCONJ
fnp-3528	461	148	neuropathology	neuropathology	NOUN
fnp-3528	461	149	lab	lab	NOUN
fnp-3528	461	150	,	,	PUNCT
fnp-3528	461	151	university	university	NOUN
fnp-3528	461	152	of	of	ADP
fnp-3528	461	153	oslo	oslo	PROPN
fnp-3528	461	154	and	and	CCONJ
fnp-3528	461	155	oslo	oslo	PROPN
fnp-3528	461	156	university	university	PROPN
fnp-3528	461	157	hospital	hospital	NOUN
fnp-3528	461	158	,	,	PUNCT
fnp-3528	461	159	sognsvannsveien	sognsvannsveien	NOUN
fnp-3528	461	160	20	20	NUM
fnp-3528	461	161	,	,	PUNCT
fnp-3528	461	162	0372	0372	NUM
fnp-3528	461	163	oslo	oslo	PROPN
fnp-3528	461	164	,	,	PUNCT
fnp-3528	461	165	norway	norway	PROPN
fnp-3528	461	166	;	;	PUNCT
fnp-3528	461	167	orcid	orcid	NUM
fnp-3528	461	168	:	:	PUNCT
fnp-3528	461	169	0000	0000	NUM
fnp-3528	461	170	-	-	PUNCT
fnp-3528	461	171	0003	0003	NUM
fnp-3528	461	172	-	-	PUNCT
fnp-3528	461	173	2186	2186	NUM
fnp-3528	461	174	-	-	PUNCT
fnp-3528	461	175	8899	8899	NUM
fnp-3528	461	176	mirjam	mirjam	NOUN
fnp-3528	461	177	brackhan	brackhan	PROPN
fnp-3528	461	178	,	,	PUNCT
fnp-3528	461	179	department	department	NOUN
fnp-3528	461	180	of	of	ADP
fnp-3528	461	181	pathology	pathology	PROPN
fnp-3528	461	182	,	,	PUNCT
fnp-3528	461	183	section	section	NOUN
fnp-3528	461	184	of	of	ADP
fnp-3528	461	185	neuropathology	neuropathology	NOUN
fnp-3528	461	186	,	,	PUNCT
fnp-3528	461	187	translational	translational	ADJ
fnp-3528	461	188	neurodeg	neurodeg	ADJ
fnp-3528	461	189	-	-	PUNCT
fnp-3528	461	190	eneration	eneration	NOUN
fnp-3528	461	191	research	research	NOUN
fnp-3528	461	192	and	and	CCONJ
fnp-3528	461	193	neuropathology	neuropathology	NOUN
fnp-3528	461	194	lab	lab	NOUN
fnp-3528	461	195	,	,	PUNCT
fnp-3528	461	196	university	university	NOUN
fnp-3528	461	197	of	of	ADP
fnp-3528	461	198	oslo	oslo	PROPN
fnp-3528	461	199	and	and	CCONJ
fnp-3528	461	200	oslo	oslo	PROPN
fnp-3528	461	201	university	university	PROPN
fnp-3528	461	202	hospital	hospital	NOUN
fnp-3528	461	203	,	,	PUNCT
fnp-3528	461	204	sognsvannsveien	sognsvannsveien	NOUN
fnp-3528	461	205	20	20	NUM
fnp-3528	461	206	,	,	PUNCT
fnp-3528	461	207	0372	0372	NUM
fnp-3528	461	208	oslo	oslo	PROPN
fnp-3528	461	209	,	,	PUNCT
fnp-3528	461	210	norway	norway	PROPN
fnp-3528	461	211	;	;	PUNCT
fnp-3528	461	212	lied	lie	VERB
fnp-3528	461	213	,	,	PUNCT
fnp-3528	461	214	university	university	NOUN
fnp-3528	461	215	of	of	ADP
fnp-3528	461	216	lübeck	lübeck	PROPN
fnp-3528	461	217	,	,	PUNCT
fnp-3528	461	218	ratzenburger	ratzenburger	NOUN
fnp-3528	461	219	allee	allee	PROPN
fnp-3528	461	220	160	160	NUM
fnp-3528	461	221	,	,	PUNCT
fnp-3528	461	222	23538	23538	NUM
fnp-3528	461	223	lübeck	lübeck	PROPN
fnp-3528	461	224	,	,	PUNCT
fnp-3528	461	225	germany	germany	PROPN
fnp-3528	461	226	;	;	PUNCT
fnp-3528	461	227	orcid	orcid	NUM
fnp-3528	461	228	:	:	PUNCT
fnp-3528	461	229	0000	0000	NUM
fnp-3528	461	230	-	-	PUNCT
fnp-3528	461	231	0002	0002	NUM
fnp-3528	461	232	-	-	PUNCT
fnp-3528	461	233	0753	0753	NUM
fnp-3528	461	234	-	-	SYM
fnp-3528	461	235	6292	6292	NUM
fnp-3528	461	236	katja	katja	PROPN
fnp-3528	461	237	stefan	stefan	PROPN
fnp-3528	461	238	,	,	PUNCT
fnp-3528	461	239	department	department	PROPN
fnp-3528	461	240	of	of	ADP
fnp-3528	461	241	pathology	pathology	PROPN
fnp-3528	461	242	,	,	PUNCT
fnp-3528	461	243	section	section	NOUN
fnp-3528	461	244	of	of	ADP
fnp-3528	461	245	neuropathology	neuropathology	NOUN
fnp-3528	461	246	,	,	PUNCT
fnp-3528	461	247	translational	translational	ADJ
fnp-3528	461	248	neurodegeneration	neurodegeneration	NOUN
fnp-3528	461	249	research	research	NOUN
fnp-3528	461	250	and	and	CCONJ
fnp-3528	461	251	neuropathology	neuropathology	NOUN
fnp-3528	461	252	lab	lab	NOUN
fnp-3528	461	253	,	,	PUNCT
fnp-3528	461	254	university	university	NOUN
fnp-3528	461	255	of	of	ADP
fnp-3528	461	256	oslo	oslo	PROPN
fnp-3528	461	257	and	and	CCONJ
fnp-3528	461	258	oslo	oslo	PROPN
fnp-3528	461	259	university	university	PROPN
fnp-3528	461	260	hospital	hospital	NOUN
fnp-3528	461	261	,	,	PUNCT
fnp-3528	461	262	sognsvannsveien	sognsvannsveien	NOUN
fnp-3528	461	263	20	20	NUM
fnp-3528	461	264	,	,	PUNCT
fnp-3528	461	265	0372	0372	NUM
fnp-3528	461	266	oslo	oslo	PROPN
fnp-3528	461	267	,	,	PUNCT
fnp-3528	461	268	norway	norway	PROPN
fnp-3528	461	269	;	;	PUNCT
fnp-3528	461	270	orcid	orcid	NUM
fnp-3528	461	271	:	:	PUNCT
fnp-3528	461	272	0000	0000	NUM
fnp-3528	461	273	-	-	PUNCT
fnp-3528	461	274	0003	0003	NUM
fnp-3528	461	275	-	-	PUNCT
fnp-3528	461	276	3544	3544	NUM
fnp-3528	461	277	-	-	SYM
fnp-3528	461	278	2477	2477	NUM
fnp-3528	461	279	vigneshwaran	vigneshwaran	NOUN
fnp-3528	461	280	namasivayam	namasivayam	PROPN
fnp-3528	461	281	,	,	PUNCT
fnp-3528	461	282	department	department	NOUN
fnp-3528	461	283	of	of	ADP
fnp-3528	461	284	pharmaceutical	pharmaceutical	ADJ
fnp-3528	461	285	and	and	CCONJ
fnp-3528	461	286	cellbiological	cellbiological	ADJ
fnp-3528	461	287	chemistry	chemistry	NOUN
fnp-3528	461	288	,	,	PUNCT
fnp-3528	461	289	pharmaceutical	pharmaceutical	PROPN
fnp-3528	461	290	institute	institute	PROPN
fnp-3528	461	291	,	,	PUNCT
fnp-3528	461	292	university	university	PROPN
fnp-3528	461	293	of	of	ADP
fnp-3528	461	294	bonn	bonn	PROPN
fnp-3528	461	295	,	,	PUNCT
fnp-3528	461	296	an	an	DET
fnp-3528	461	297	der	der	NOUN
fnp-3528	461	298	immenburg	immenburg	NOUN
fnp-3528	461	299	4	4	NUM
fnp-3528	461	300	,	,	PUNCT
fnp-3528	461	301	53121	53121	NUM
fnp-3528	461	302	bonn	bonn	X
fnp-3528	461	303	,	,	PUNCT
fnp-3528	461	304	germany	germany	PROPN
fnp-3528	461	305	;	;	PUNCT
fnp-3528	461	306	orcid	orcid	NUM
fnp-3528	461	307	:	:	PUNCT
fnp-3528	461	308	0000	0000	NUM
fnp-3528	461	309	-	-	PUNCT
fnp-3528	461	310	0003	0003	NUM
fnp-3528	461	311	-	-	PUNCT
fnp-3528	461	312	3031	3031	NUM
fnp-3528	461	313	-	-	PUNCT
fnp-3528	461	314	3377	3377	NUM
fnp-3528	461	315	radosveta	radosveta	NOUN
fnp-3528	461	316	koldamova	koldamova	PROPN
fnp-3528	461	317	,	,	PUNCT
fnp-3528	461	318	department	department	NOUN
fnp-3528	461	319	of	of	ADP
fnp-3528	461	320	environmental	environmental	ADJ
fnp-3528	461	321	and	and	CCONJ
fnp-3528	461	322	occupational	occupational	ADJ
fnp-3528	461	323	health	health	NOUN
fnp-3528	461	324	,	,	PUNCT
fnp-3528	461	325	school	school	NOUN
fnp-3528	461	326	of	of	ADP
fnp-3528	461	327	public	public	ADJ
fnp-3528	461	328	health	health	NOUN
fnp-3528	461	329	,	,	PUNCT
fnp-3528	461	330	university	university	PROPN
fnp-3528	461	331	of	of	ADP
fnp-3528	461	332	pittsburgh	pittsburgh	PROPN
fnp-3528	461	333	,	,	PUNCT
fnp-3528	461	334	130	130	NUM
fnp-3528	461	335	de	de	PROPN
fnp-3528	461	336	soto	soto	PROPN
fnp-3528	461	337	street	street	PROPN
fnp-3528	461	338	,	,	PUNCT
fnp-3528	461	339	pittsburgh	pittsburgh	PROPN
fnp-3528	461	340	,	,	PUNCT
fnp-3528	461	341	pa	pa	PROPN
fnp-3528	461	342	15261	15261	NUM
fnp-3528	461	343	,	,	PUNCT
fnp-3528	461	344	united	united	PROPN
fnp-3528	461	345	states	states	PROPN
fnp-3528	461	346	of	of	ADP
fnp-3528	461	347	america	america	PROPN
fnp-3528	461	348	;	;	PUNCT
fnp-3528	461	349	orcid	orcid	NUM
fnp-3528	461	350	:	:	PUNCT
fnp-3528	461	351	0000	0000	NUM
fnp-3528	461	352	-	-	PUNCT
fnp-3528	461	353	0002	0002	NUM
fnp-3528	461	354	-	-	PUNCT
fnp-3528	461	355	6761	6761	NUM
fnp-3528	461	356	-	-	SYM
fnp-3528	461	357	0984	0984	NUM
fnp-3528	461	358	jingyun	jingyun	PROPN
fnp-3528	461	359	wu	wu	PROPN
fnp-3528	461	360	,	,	PUNCT
fnp-3528	461	361	department	department	NOUN
fnp-3528	461	362	of	of	ADP
fnp-3528	461	363	pathology	pathology	PROPN
fnp-3528	461	364	,	,	PUNCT
fnp-3528	461	365	section	section	NOUN
fnp-3528	461	366	of	of	ADP
fnp-3528	461	367	neuropathology	neuropathology	NOUN
fnp-3528	461	368	,	,	PUNCT
fnp-3528	461	369	translational	translational	ADJ
fnp-3528	461	370	neurodegeneration	neurodegeneration	NOUN
fnp-3528	461	371	research	research	NOUN
fnp-3528	461	372	and	and	CCONJ
fnp-3528	461	373	neuropathology	neuropathology	NOUN
fnp-3528	461	374	lab	lab	NOUN
fnp-3528	461	375	,	,	PUNCT
fnp-3528	461	376	university	university	NOUN
fnp-3528	461	377	of	of	ADP
fnp-3528	461	378	oslo	oslo	PROPN
fnp-3528	461	379	and	and	CCONJ
fnp-3528	461	380	oslo	oslo	PROPN
fnp-3528	461	381	university	university	PROPN
fnp-3528	461	382	hospital	hospital	NOUN
fnp-3528	461	383	,	,	PUNCT
fnp-3528	461	384	sognsvannsveien	sognsvannsveien	NOUN
fnp-3528	461	385	20	20	NUM
fnp-3528	461	386	,	,	PUNCT
fnp-3528	461	387	0372	0372	NUM
fnp-3528	461	388	oslo	oslo	PROPN
fnp-3528	461	389	,	,	PUNCT
fnp-3528	461	390	norway	norway	PROPN
fnp-3528	461	391	;	;	PUNCT
fnp-3528	461	392	orcid	orcid	NUM
fnp-3528	461	393	:	:	PUNCT
fnp-3528	461	394	0000	0000	NUM
fnp-3528	461	395	-	-	PUNCT
fnp-3528	461	396	0002	0002	NUM
fnp-3528	461	397	-	-	PUNCT
fnp-3528	461	398	5137	5137	NUM
fnp-3528	461	399	-	-	SYM
fnp-3528	461	400	4614	4614	NUM
fnp-3528	461	401	luisa	luisa	PROPN
fnp-3528	461	402	möhle	möhle	PROPN
fnp-3528	461	403	,	,	PUNCT
fnp-3528	461	404	department	department	NOUN
fnp-3528	461	405	of	of	ADP
fnp-3528	461	406	pathology	pathology	PROPN
fnp-3528	461	407	,	,	PUNCT
fnp-3528	461	408	section	section	NOUN
fnp-3528	461	409	of	of	ADP
fnp-3528	461	410	neuropathology	neuropathology	NOUN
fnp-3528	461	411	,	,	PUNCT
fnp-3528	461	412	translational	translational	ADJ
fnp-3528	461	413	neurodege	neurodege	ADJ
fnp-3528	461	414	-	-	PUNCT
fnp-3528	461	415	neration	neration	NOUN
fnp-3528	461	416	research	research	NOUN
fnp-3528	461	417	and	and	CCONJ
fnp-3528	461	418	neuropathology	neuropathology	NOUN
fnp-3528	461	419	lab	lab	NOUN
fnp-3528	461	420	,	,	PUNCT
fnp-3528	461	421	university	university	NOUN
fnp-3528	461	422	of	of	ADP
fnp-3528	461	423	oslo	oslo	PROPN
fnp-3528	461	424	and	and	CCONJ
fnp-3528	461	425	oslo	oslo	PROPN
fnp-3528	461	426	university	university	PROPN
fnp-3528	461	427	hospital	hospital	NOUN
fnp-3528	461	428	,	,	PUNCT
fnp-3528	461	429	sognsvannsveien	sognsvannsveien	NOUN
fnp-3528	461	430	20	20	NUM
fnp-3528	461	431	,	,	PUNCT
fnp-3528	461	432	0372	0372	NUM
fnp-3528	461	433	oslo	oslo	PROPN
fnp-3528	461	434	,	,	PUNCT
fnp-3528	461	435	norway	norway	PROPN
fnp-3528	461	436	;	;	PUNCT
fnp-3528	461	437	orcid	orcid	NUM
fnp-3528	461	438	:	:	PUNCT
fnp-3528	461	439	0000	0000	NUM
fnp-3528	461	440	-	-	PUNCT
fnp-3528	461	441	0002	0002	NUM
fnp-3528	461	442	-	-	PUNCT
fnp-3528	461	443	4535	4535	NUM
fnp-3528	461	444	-	-	PUNCT
fnp-3528	461	445	9952	9952	NUM
fnp-3528	461	446	conflict	conflict	NOUN
fnp-3528	461	447	of	of	ADP
fnp-3528	461	448	interest	interest	NOUN
fnp-3528	461	449	the	the	DET
fnp-3528	461	450	authors	author	NOUN
fnp-3528	461	451	declare	declare	VERB
fnp-3528	461	452	that	that	SCONJ
fnp-3528	461	453	they	they	PRON
fnp-3528	461	454	have	have	VERB
fnp-3528	461	455	no	no	DET
fnp-3528	461	456	conflict	conflict	NOUN
fnp-3528	461	457	of	of	ADP
fnp-3528	461	458	interest	interest	NOUN
fnp-3528	461	459	.	.	PUNCT
fnp-3528	462	1	funding	funding	NOUN
fnp-3528	462	2	jp	jp	NOUN
fnp-3528	462	3	received	receive	VERB
fnp-3528	462	4	funding	funding	NOUN
fnp-3528	462	5	from	from	ADP
fnp-3528	462	6	deutsche	deutsche	PROPN
fnp-3528	462	7	forschungsgemeinschaft	forschungsgemeinschaft	NOUN
fnp-3528	462	8	(	(	PUNCT
fnp-3528	462	9	dfg	dfg	PROPN
fnp-3528	462	10	,	,	PUNCT
fnp-3528	462	11	german	german	ADJ
fnp-3528	462	12	research	research	NOUN
fnp-3528	462	13	foundation	foundation	PROPN
fnp-3528	462	14	;	;	PUNCT
fnp-3528	462	15	germany	germany	PROPN
fnp-3528	462	16	;	;	PUNCT
fnp-3528	462	17	263024513	263024513	NUM
fnp-3528	462	18	)	)	PUNCT
fnp-3528	462	19	;	;	PUNCT
fnp-3528	462	20	latvian	latvian	ADJ
fnp-3528	462	21	council	council	PROPN
fnp-3528	462	22	of	of	ADP
fnp-3528	462	23	science	science	PROPN
fnp-3528	462	24	(	(	PUNCT
fnp-3528	462	25	latvia	latvia	PROPN
fnp-3528	462	26	;	;	PUNCT
fnp-3528	462	27	lzp-2018/1	lzp-2018/1	NUM
fnp-3528	462	28	-	-	PUNCT
fnp-3528	462	29	0275	0275	NUM
fnp-3528	462	30	)	)	PUNCT
fnp-3528	462	31	;	;	PUNCT
fnp-3528	462	32	helsesø	helsesø	NOUN
fnp-3528	462	33	(	(	PUNCT
fnp-3528	462	34	norway	norway	PROPN
fnp-3528	462	35	;	;	PUNCT
fnp-3528	462	36	2019054	2019054	NUM
fnp-3528	462	37	,	,	PUNCT
fnp-3528	462	38	2019055	2019055	NUM
fnp-3528	462	39	)	)	PUNCT
fnp-3528	462	40	;	;	PUNCT
fnp-3528	462	41	barnekreftforeningen	barnekreftforeningen	NOUN
fnp-3528	462	42	(	(	PUNCT
fnp-3528	462	43	norway	norway	PROPN
fnp-3528	462	44	;	;	PUNCT
fnp-3528	462	45	19008	19008	NUM
fnp-3528	462	46	)	)	PUNCT
fnp-3528	462	47	;	;	PUNCT
fnp-3528	462	48	eea	eea	PROPN
fnp-3528	462	49	grant	grant	PROPN
fnp-3528	462	50	/	/	SYM
fnp-3528	462	51	norway	norway	PROPN
fnp-3528	462	52	grants	grant	NOUN
fnp-3528	462	53	kappa	kappa	VERB
fnp-3528	462	54	programme	programme	PROPN
fnp-3528	462	55	(	(	PUNCT
fnp-3528	462	56	iceland	iceland	PROPN
fnp-3528	462	57	,	,	PUNCT
fnp-3528	462	58	liechtenstein	liechtenstein	PROPN
fnp-3528	462	59	,	,	PUNCT
fnp-3528	462	60	norway	norway	PROPN
fnp-3528	462	61	;	;	PUNCT
fnp-3528	462	62	tačr	tačr	PROPN
fnp-3528	462	63	tarimad	tarimad	NOUN
fnp-3528	462	64	to100078	to100078	NOUN
fnp-3528	462	65	)	)	PUNCT
fnp-3528	462	66	;	;	PUNCT
fnp-3528	462	67	norges	norge	NOUN
fnp-3528	462	68	forskningsråd	forskningsråd	VERB
fnp-3528	462	69	[	[	X
fnp-3528	462	70	norway	norway	NOUN
fnp-3528	462	71	;	;	PUNCT
fnp-3528	462	72	260786	260786	NUM
fnp-3528	462	73	(	(	PUNCT
fnp-3528	462	74	prop	prop	NOUN
fnp-3528	462	75	-	-	PUNCT
fnp-3528	462	76	ad	ad	NOUN
fnp-3528	462	77	)	)	PUNCT
fnp-3528	462	78	,	,	PUNCT
fnp-3528	462	79	295910	295910	NUM
fnp-3528	462	80	(	(	PUNCT
fnp-3528	462	81	napi	napi	NOUN
fnp-3528	462	82	)	)	PUNCT
fnp-3528	462	83	,	,	PUNCT
fnp-3528	462	84	and	and	CCONJ
fnp-3528	462	85	327571	327571	NUM
fnp-3528	462	86	(	(	PUNCT
fnp-3528	462	87	petabc	petabc	PROPN
fnp-3528	462	88	)	)	PUNCT
fnp-3528	462	89	]	]	PUNCT
fnp-3528	462	90	;	;	PUNCT
fnp-3528	462	91	european	european	ADJ
fnp-3528	462	92	commission	commission	PROPN
fnp-3528	462	93	(	(	PUNCT
fnp-3528	462	94	european	european	PROPN
fnp-3528	462	95	union	union	PROPN
fnp-3528	462	96	;	;	PUNCT
fnp-3528	462	97	643417	643417	NUM
fnp-3528	462	98	)	)	PUNCT
fnp-3528	462	99	.	.	PUNCT
fnp-3528	463	1	prop	prop	NOUN
fnp-3528	463	2	-	-	PUNCT
fnp-3528	463	3	ad	ad	NOUN
fnp-3528	463	4	and	and	CCONJ
fnp-3528	463	5	petabc	petabc	NOUN
fnp-3528	463	6	are	be	AUX
fnp-3528	463	7	eu	eu	PROPN
fnp-3528	463	8	joint	joint	ADJ
fnp-3528	463	9	programme	programme	NOUN
fnp-3528	463	10	neurodegenerative	neurodegenerative	ADJ
fnp-3528	463	11	disease	disease	NOUN
fnp-3528	463	12	research	research	NOUN
fnp-3528	463	13	(	(	PUNCT
fnp-3528	463	14	jpnd	jpnd	NOUN
fnp-3528	463	15	)	)	PUNCT
fnp-3528	463	16	projects	project	NOUN
fnp-3528	463	17	.	.	PUNCT
fnp-3528	464	1	prop	prop	NOUN
fnp-3528	464	2	-	-	PUNCT
fnp-3528	464	3	ad	ad	NOUN
fnp-3528	464	4	is	be	AUX
fnp-3528	464	5	supported	support	VERB
fnp-3528	464	6	through	through	ADP
fnp-3528	464	7	the	the	DET
fnp-3528	464	8	following	follow	VERB
fnp-3528	464	9	funding	funding	NOUN
fnp-3528	464	10	organizations	organization	NOUN
fnp-3528	464	11	under	under	ADP
fnp-3528	464	12	the	the	DET
fnp-3528	464	13	aegis	aegis	NOUN
fnp-3528	464	14	of	of	ADP
fnp-3528	464	15	jpnd	jpnd	NOUN
fnp-3528	464	16	–	–	PUNCT
fnp-3528	464	17	www.jpnd.eu	www.jpnd.eu	NOUN
fnp-3528	464	18	:	:	PUNCT
fnp-3528	464	19	aka	aka	ADV
fnp-3528	464	20	#	#	SYM
fnp-3528	464	21	301228	301228	NUM
fnp-3528	464	22	–	–	PUNCT
fnp-3528	464	23	finland	finland	PROPN
fnp-3528	464	24	,	,	PUNCT
fnp-3528	464	25	bmbf	bmbf	NOUN
fnp-3528	464	26	#	#	SYM
fnp-3528	464	27	01ed1605	01ed1605	NUM
fnp-3528	464	28	–	–	PUNCT
fnp-3528	464	29	germany	germany	PROPN
fnp-3528	464	30	;	;	PUNCT
fnp-3528	464	31	cso	cso	PROPN
fnp-3528	464	32	-	-	PUNCT
fnp-3528	464	33	moh	moh	PROPN
fnp-3528	464	34	#	#	SYM
fnp-3528	464	35	30000	30000	NUM
fnp-3528	464	36	-	-	SYM
fnp-3528	464	37	12631	12631	NUM
fnp-3528	464	38	–	–	PUNCT
fnp-3528	464	39	israel	israel	PROPN
fnp-3528	464	40	;	;	PUNCT
fnp-3528	464	41	nfr	nfr	PROPN
fnp-3528	464	42	#	#	SYM
fnp-3528	464	43	260786	260786	NUM
fnp-3528	464	44	–	–	PUNCT
fnp-3528	464	45	norway	norway	NOUN
fnp-3528	464	46	;	;	PUNCT
fnp-3528	464	47	src	src	NOUN
fnp-3528	464	48	#	#	SYM
fnp-3528	464	49	2015	2015	NUM
fnp-3528	464	50	-	-	SYM
fnp-3528	464	51	06795	06795	NUM
fnp-3528	464	52	–	–	PUNCT
fnp-3528	464	53	sweden	sweden	PROPN
fnp-3528	464	54	)	)	PUNCT
fnp-3528	464	55	.	.	PUNCT
fnp-3528	465	1	petabc	petabc	PROPN
fnp-3528	465	2	is	be	AUX
fnp-3528	465	3	supported	support	VERB
fnp-3528	465	4	through	through	ADP
fnp-3528	465	5	the	the	DET
fnp-3528	465	6	following	follow	VERB
fnp-3528	465	7	funding	funding	NOUN
fnp-3528	465	8	organizations	organization	NOUN
fnp-3528	465	9	under	under	ADP
fnp-3528	465	10	the	the	DET
fnp-3528	465	11	aegis	aegis	NOUN
fnp-3528	465	12	of	of	ADP
fnp-3528	465	13	jpnd	jpnd	NOUN
fnp-3528	465	14	–	–	PUNCT
fnp-3528	465	15	www.jpnd.eu	www.jpnd.eu	NOUN
fnp-3528	465	16	:	:	PUNCT
fnp-3528	465	17	nfr	nfr	PROPN
fnp-3528	465	18	#	#	SYM
fnp-3528	465	19	327571	327571	NUM
fnp-3528	465	20	–	–	PUNCT
fnp-3528	465	21	norway	norway	NOUN
fnp-3528	465	22	;	;	PUNCT
fnp-3528	465	23	ffg	ffg	PROPN
fnp-3528	465	24	#	#	SYM
fnp-3528	465	25	882717	882717	NUM
fnp-3528	465	26	–	–	PUNCT
fnp-3528	465	27	austria	austria	NOUN
fnp-3528	465	28	;	;	PUNCT
fnp-3528	465	29	bmbf	bmbf	NOUN
fnp-3528	465	30	#	#	SYM
fnp-3528	465	31	01ed2106	01ed2106	NUM
fnp-3528	465	32	–	–	PUNCT
fnp-3528	465	33	germany	germany	PROPN
fnp-3528	465	34	;	;	PUNCT
fnp-3528	465	35	msmt	msmt	VERB
fnp-3528	465	36	#	#	SYM
fnp-3528	465	37	8f21002	8f21002	NOUN
fnp-3528	465	38	–	–	PUNCT
fnp-3528	465	39	czech	czech	ADJ
fnp-3528	465	40	republic	republic	NOUN
fnp-3528	465	41	;	;	PUNCT
fnp-3528	465	42	viaa	viaa	VERB
fnp-3528	465	43	#	#	SYM
fnp-3528	465	44	es	es	ADP
fnp-3528	465	45	rtd/2020/26	rtd/2020/26	PROPN
fnp-3528	465	46	–	–	PUNCT
fnp-3528	465	47	latvia	latvia	PROPN
fnp-3528	465	48	;	;	PUNCT
fnp-3528	465	49	anr	anr	PROPN
fnp-3528	465	50	#	#	SYM
fnp-3528	465	51	20	20	NUM
fnp-3528	465	52	-	-	PUNCT
fnp-3528	465	53	jpw2	jpw2	NOUN
fnp-3528	465	54	-	-	PUNCT
fnp-3528	465	55	0002	0002	NUM
fnp-3528	465	56	-	-	PUNCT
fnp-3528	465	57	04	04	NUM
fnp-3528	465	58	–	–	PUNCT
fnp-3528	465	59	france	france	PROPN
fnp-3528	465	60	,	,	PUNCT
fnp-3528	465	61	src	src	NOUN
fnp-3528	465	62	#	#	SYM
fnp-3528	465	63	2020	2020	NUM
fnp-3528	465	64	-	-	SYM
fnp-3528	465	65	02905	02905	NUM
fnp-3528	465	66	–	–	PUNCT
fnp-3528	465	67	sweden	sweden	ADJ
fnp-3528	465	68	.	.	PUNCT
fnp-3528	466	1	the	the	DET
fnp-3528	466	2	projects	project	NOUN
fnp-3528	466	3	receive	receive	VERB
fnp-3528	466	4	funding	funding	NOUN
fnp-3528	466	5	from	from	ADP
fnp-3528	466	6	the	the	DET
fnp-3528	466	7	european	european	PROPN
fnp-3528	466	8	union	union	PROPN
fnp-3528	466	9	’s	’s	PART
fnp-3528	466	10	horizon	horizon	NOUN
fnp-3528	466	11	2020	2020	NUM
fnp-3528	466	12	research	research	NOUN
fnp-3528	466	13	and	and	CCONJ
fnp-3528	466	14	innovation	innovation	NOUN
fnp-3528	466	15	programme	programme	NOUN
fnp-3528	466	16	under	under	ADP
fnp-3528	466	17	grant	grant	NOUN
fnp-3528	466	18	agreement	agreement	NOUN
fnp-3528	466	19	#	#	SYM
fnp-3528	466	20	643417	643417	NUM
fnp-3528	466	21	(	(	PUNCT
fnp-3528	466	22	jpco	jpco	NOUN
fnp-3528	466	23	-	-	PUNCT
fnp-3528	466	24	fund	fund	NOUN
fnp-3528	466	25	)	)	PUNCT
fnp-3528	466	26	.	.	PUNCT
fnp-3528	467	1	ks	k	NOUN
fnp-3528	467	2	receives	receive	VERB
fnp-3528	467	3	a	a	DET
fnp-3528	467	4	walter	walter	NOUN
fnp-3528	467	5	benjamin	benjamin	PROPN
fnp-3528	467	6	fellowship	fellowship	NOUN
fnp-3528	467	7	of	of	ADP
fnp-3528	467	8	the	the	DET
fnp-3528	467	9	dfg	dfg	PROPN
fnp-3528	467	10	(	(	PUNCT
fnp-3528	467	11	germany	germany	PROPN
fnp-3528	467	12	;	;	PUNCT
fnp-3528	467	13	466106904	466106904	NUM
fnp-3528	467	14	)	)	PUNCT
fnp-3528	467	15	.	.	PUNCT
fnp-3528	468	1	rk	rk	NOUN
fnp-3528	468	2	is	be	AUX
fnp-3528	468	3	funded	fund	VERB
fnp-3528	468	4	by	by	ADP
fnp-3528	468	5	the	the	DET
fnp-3528	468	6	national	national	PROPN
fnp-3528	468	7	institute	institute	PROPN
fnp-3528	468	8	of	of	ADP
fnp-3528	468	9	health	health	PROPN
fnp-3528	468	10	(	(	PUNCT
fnp-3528	468	11	nih	nih	PROPN
fnp-3528	468	12	;	;	PUNCT
fnp-3528	468	13	united	united	PROPN
fnp-3528	468	14	states	states	PROPN
fnp-3528	468	15	;	;	PUNCT
fnp-3528	468	16	ag056371	ag056371	NOUN
fnp-3528	468	17	,	,	PUNCT
fnp-3528	468	18	ag057565	ag057565	ADV
fnp-3528	468	19	;	;	PUNCT
fnp-3528	468	20	ag066198	ag066198	NOUN
fnp-3528	468	21	)	)	PUNCT
fnp-3528	468	22	.	.	PUNCT
fnp-3528	469	1	lm	lm	PROPN
fnp-3528	469	2	is	be	AUX
fnp-3528	469	3	supported	support	VERB
fnp-3528	469	4	by	by	ADP
fnp-3528	469	5	the	the	DET
fnp-3528	469	6	norwegian	norwegian	ADJ
fnp-3528	469	7	health	health	PROPN
fnp-3528	469	8	association	association	NOUN
fnp-3528	469	9	(	(	PUNCT
fnp-3528	469	10	nasjonalforeningen	nasjonalforeningen	NOUN
fnp-3528	469	11	for	for	ADP
fnp-3528	469	12	folkehelsen	folkehelsen	ADJ
fnp-3528	469	13	;	;	PUNCT
fnp-3528	469	14	norway	norway	PROPN
fnp-3528	469	15	;	;	PUNCT
fnp-3528	469	16	#	#	SYM
fnp-3528	469	17	16154	16154	NUM
fnp-3528	469	18	)	)	PUNCT
fnp-3528	469	19	.	.	PUNCT
fnp-3528	470	1	sms	sms	PROPN
fnp-3528	470	2	receives	receive	VERB
fnp-3528	470	3	a	a	DET
fnp-3528	470	4	walter	walter	NOUN
fnp-3528	470	5	benjamin	benjamin	PROPN
fnp-3528	470	6	fellowship	fellowship	NOUN
fnp-3528	470	7	of	of	ADP
fnp-3528	470	8	the	the	DET
fnp-3528	470	9	dfg	dfg	PROPN
fnp-3528	470	10	(	(	PUNCT
fnp-3528	470	11	germany	germany	PROPN
fnp-3528	470	12	;	;	PUNCT
fnp-3528	470	13	446812474	446812474	NUM
fnp-3528	470	14	)	)	PUNCT
fnp-3528	470	15	.	.	PUNCT
fnp-3528	471	1	acknowledgement	acknowledgement	NOUN
fnp-3528	471	2	the	the	DET
fnp-3528	471	3	authors	author	NOUN
fnp-3528	471	4	would	would	AUX
fnp-3528	471	5	like	like	VERB
fnp-3528	471	6	to	to	PART
fnp-3528	471	7	cordially	cordially	ADV
fnp-3528	471	8	thank	thank	VERB
fnp-3528	471	9	joseph	joseph	PROPN
fnp-3528	471	10	mark	mark	PROPN
fnp-3528	471	11	robertson	robertson	PROPN
fnp-3528	471	12	(	(	PUNCT
fnp-3528	471	13	napi	napi	PROPN
fnp-3528	471	14	/	/	SYM
fnp-3528	471	15	department	department	NOUN
fnp-3528	471	16	of	of	ADP
fnp-3528	471	17	immunology	immunology	NOUN
fnp-3528	471	18	,	,	PUNCT
fnp-3528	471	19	university	university	NOUN
fnp-3528	471	20	of	of	ADP
fnp-3528	471	21	oslo	oslo	PROPN
fnp-3528	471	22	and	and	CCONJ
fnp-3528	471	23	oslo	oslo	PROPN
fnp-3528	471	24	university	university	PROPN
fnp-3528	471	25	hospital	hospital	NOUN
fnp-3528	471	26	)	)	PUNCT
fnp-3528	471	27	for	for	ADP
fnp-3528	471	28	proofreading	proofread	VERB
fnp-3528	471	29	the	the	DET
fnp-3528	471	30	manuscript	manuscript	NOUN
fnp-3528	471	31	.	.	PUNCT
fnp-3528	472	1	references	reference	NOUN
fnp-3528	472	2	wang	wang	PROPN
fnp-3528	472	3	,	,	PUNCT
fnp-3528	472	4	j.	j.	PROPN
fnp-3528	472	5	q.	q.	PROPN
fnp-3528	472	6	;	;	PUNCT
fnp-3528	472	7	yang	yang	PROPN
fnp-3528	472	8	,	,	PUNCT
fnp-3528	472	9	y.	y.	PROPN
fnp-3528	472	10	;	;	PUNCT
fnp-3528	472	11	cai	cai	X
fnp-3528	472	12	,	,	PUNCT
fnp-3528	472	13	c.	c.	PROPN
fnp-3528	472	14	y.	y.	PROPN
fnp-3528	472	15	;	;	PUNCT
fnp-3528	472	16	teng	teng	PROPN
fnp-3528	472	17	,	,	PUNCT
fnp-3528	472	18	q.	q.	PROPN
fnp-3528	472	19	x.	x.	PROPN
fnp-3528	472	20	;	;	PUNCT
fnp-3528	472	21	cui	cui	PROPN
fnp-3528	472	22	,	,	PUNCT
fnp-3528	472	23	q.	q.	PROPN
fnp-3528	472	24	;	;	PUNCT
fnp-3528	472	25	lin	lin	PROPN
fnp-3528	472	26	,	,	PUNCT
fnp-3528	472	27	j.	j.	PROPN
fnp-3528	472	28	;	;	PUNCT
fnp-3528	472	29	assaraf	assaraf	NOUN
fnp-3528	472	30	,	,	PUNCT
fnp-3528	472	31	y.	y.	PROPN
fnp-3528	472	32	g.	g.	PROPN
fnp-3528	472	33	;	;	PUNCT
fnp-3528	472	34	chen	chen	PROPN
fnp-3528	472	35	,	,	PUNCT
fnp-3528	472	36	z.	z.	PROPN
fnp-3528	472	37	s.	s.	PROPN
fnp-3528	472	38	multidrug	multidrug	VERB
fnp-3528	472	39	resistance	resistance	NOUN
fnp-3528	472	40	proteins	protein	NOUN
fnp-3528	472	41	(	(	PUNCT
fnp-3528	472	42	mrps	mrps	PROPN
fnp-3528	472	43	):	):	PUNCT
fnp-3528	472	44	structure	structure	NOUN
fnp-3528	472	45	,	,	PUNCT
fnp-3528	472	46	function	function	NOUN
fnp-3528	472	47	and	and	CCONJ
fnp-3528	472	48	the	the	DET
fnp-3528	472	49	overcoming	overcoming	NOUN
fnp-3528	472	50	of	of	ADP
fnp-3528	472	51	cancer	cancer	NOUN
fnp-3528	472	52	multidrug	multidrug	NOUN
fnp-3528	472	53	resistance	resistance	NOUN
fnp-3528	472	54	.	.	PUNCT
fnp-3528	473	1	drug	drug	NOUN
fnp-3528	473	2	resist	resist	VERB
fnp-3528	473	3	updat	updat	PROPN
fnp-3528	473	4	2021	2021	NUM
fnp-3528	473	5	,	,	PUNCT
fnp-3528	473	6	54	54	NUM
fnp-3528	473	7	,	,	PUNCT
fnp-3528	473	8	100743	100743	NUM
fnp-3528	473	9	.	.	PUNCT
fnp-3528	474	1	gil	gil	PROPN
fnp-3528	474	2	-	-	PUNCT
fnp-3528	474	3	martins	martins	PROPN
fnp-3528	474	4	,	,	PUNCT
fnp-3528	474	5	e.	e.	PROPN
fnp-3528	474	6	;	;	PUNCT
fnp-3528	474	7	barbosa	barbosa	PROPN
fnp-3528	474	8	,	,	PUNCT
fnp-3528	474	9	d.	d.	PROPN
fnp-3528	474	10	j.	j.	PROPN
fnp-3528	474	11	;	;	PUNCT
fnp-3528	474	12	silva	silva	PROPN
fnp-3528	474	13	,	,	PUNCT
fnp-3528	474	14	v.	v.	PROPN
fnp-3528	474	15	;	;	PUNCT
fnp-3528	474	16	remiao	remiao	PROPN
fnp-3528	474	17	,	,	PUNCT
fnp-3528	474	18	f.	f.	PROPN
fnp-3528	474	19	;	;	PUNCT
fnp-3528	474	20	silva	silva	PROPN
fnp-3528	474	21	,	,	PUNCT
fnp-3528	474	22	r.	r.	X
fnp-3528	474	23	dysfunction	dysfunction	NOUN
fnp-3528	474	24	of	of	ADP
fnp-3528	474	25	abc	abc	PROPN
fnp-3528	474	26	transporters	transporter	NOUN
fnp-3528	474	27	at	at	ADP
fnp-3528	474	28	the	the	DET
fnp-3528	474	29	blood	blood	NOUN
fnp-3528	474	30	-	-	PUNCT
fnp-3528	474	31	brain	brain	NOUN
fnp-3528	474	32	barrier	barrier	NOUN
fnp-3528	474	33	:	:	PUNCT
fnp-3528	474	34	role	role	NOUN
fnp-3528	474	35	in	in	ADP
fnp-3528	474	36	neurological	neurological	ADJ
fnp-3528	474	37	disorders	disorder	NOUN
fnp-3528	474	38	.	.	PUNCT
fnp-3528	475	1	pharmacol	pharmacol	NOUN
fnp-3528	475	2	ther	ther	ADV
fnp-3528	475	3	2020	2020	NUM
fnp-3528	475	4	,	,	PUNCT
fnp-3528	475	5	213	213	NUM
fnp-3528	475	6	,	,	PUNCT
fnp-3528	475	7	107554	107554	NUM
fnp-3528	475	8	.	.	PUNCT
fnp-3528	476	1	pasello	pasello	PROPN
fnp-3528	476	2	,	,	PUNCT
fnp-3528	476	3	m.	m.	NOUN
fnp-3528	476	4	;	;	PUNCT
fnp-3528	476	5	giudice	giudice	PROPN
fnp-3528	476	6	,	,	PUNCT
fnp-3528	476	7	a.	a.	NOUN
fnp-3528	476	8	m.	m.	NOUN
fnp-3528	476	9	;	;	PUNCT
fnp-3528	476	10	scotlandi	scotlandi	PROPN
fnp-3528	476	11	,	,	PUNCT
fnp-3528	476	12	k.	k.	PROPN
fnp-3528	477	1	the	the	DET
fnp-3528	477	2	abc	abc	PROPN
fnp-3528	477	3	subfamily	subfamily	ADV
fnp-3528	477	4	a	a	DET
fnp-3528	477	5	transporters	transporter	NOUN
fnp-3528	477	6	:	:	PUNCT
fnp-3528	477	7	multifaceted	multifaceted	ADJ
fnp-3528	477	8	players	player	NOUN
fnp-3528	477	9	with	with	ADP
fnp-3528	477	10	incipient	incipient	ADJ
fnp-3528	477	11	potentialities	potentiality	NOUN
fnp-3528	477	12	in	in	ADP
fnp-3528	477	13	cancer	cancer	NOUN
fnp-3528	477	14	.	.	PUNCT
fnp-3528	478	1	semin	semin	PROPN
fnp-3528	478	2	cancer	cancer	PROPN
fnp-3528	478	3	biol	biol	PROPN
fnp-3528	478	4	2020	2020	NUM
fnp-3528	478	5	,	,	PUNCT
fnp-3528	478	6	60	60	NUM
fnp-3528	478	7	,	,	PUNCT
fnp-3528	478	8	57	57	NUM
fnp-3528	478	9	-	-	SYM
fnp-3528	478	10	71	71	NUM
fnp-3528	478	11	.	.	PUNCT
fnp-3528	479	1	sodani	sodani	PROPN
fnp-3528	479	2	,	,	PUNCT
fnp-3528	479	3	k.	k.	PROPN
fnp-3528	479	4	;	;	PUNCT
fnp-3528	479	5	patel	patel	PROPN
fnp-3528	479	6	,	,	PUNCT
fnp-3528	479	7	a.	a.	NOUN
fnp-3528	479	8	;	;	PUNCT
fnp-3528	479	9	kathawala	kathawala	PROPN
fnp-3528	479	10	,	,	PUNCT
fnp-3528	479	11	r.	r.	PROPN
fnp-3528	479	12	j.	j.	PROPN
fnp-3528	479	13	;	;	PUNCT
fnp-3528	479	14	chen	chen	PROPN
fnp-3528	479	15	,	,	PUNCT
fnp-3528	479	16	z.	z.	PROPN
fnp-3528	479	17	s.	s.	PROPN
fnp-3528	479	18	multidrug	multidrug	VERB
fnp-3528	479	19	resistance	resistance	NOUN
fnp-3528	479	20	associated	associate	VERB
fnp-3528	479	21	proteins	protein	NOUN
fnp-3528	479	22	in	in	ADP
fnp-3528	479	23	multidrug	multidrug	NOUN
fnp-3528	479	24	resistance	resistance	NOUN
fnp-3528	479	25	.	.	PUNCT
fnp-3528	480	1	chin	chin	PROPN
fnp-3528	480	2	j	j	PROPN
fnp-3528	480	3	cancer	cancer	PROPN
fnp-3528	480	4	2012	2012	NUM
fnp-3528	480	5	,	,	PUNCT
fnp-3528	480	6	31	31	NUM
fnp-3528	480	7	,	,	PUNCT
fnp-3528	480	8	58	58	NUM
fnp-3528	480	9	-	-	SYM
fnp-3528	480	10	72	72	NUM
fnp-3528	480	11	.	.	PUNCT
fnp-3528	481	1	szakacs	szakacs	PROPN
fnp-3528	481	2	,	,	PUNCT
fnp-3528	481	3	g.	g.	PROPN
fnp-3528	481	4	;	;	PUNCT
fnp-3528	481	5	abele	abele	PROPN
fnp-3528	481	6	,	,	PUNCT
fnp-3528	481	7	r.	r.	PROPN
fnp-3528	481	8	an	an	DET
fnp-3528	481	9	inventory	inventory	NOUN
fnp-3528	481	10	of	of	ADP
fnp-3528	481	11	lysosomal	lysosomal	ADJ
fnp-3528	481	12	abc	abc	PROPN
fnp-3528	481	13	transporters	transporters	PROPN
fnp-3528	481	14	.	.	PUNCT
fnp-3528	482	1	febs	febs	PROPN
fnp-3528	482	2	lett	lett	PROPN
fnp-3528	482	3	2020	2020	NUM
fnp-3528	482	4	,	,	PUNCT
fnp-3528	482	5	594	594	NUM
fnp-3528	482	6	,	,	PUNCT
fnp-3528	482	7	3965	3965	NUM
fnp-3528	482	8	-	-	SYM
fnp-3528	482	9	85	85	NUM
fnp-3528	482	10	.	.	PUNCT
fnp-3528	483	1	stefan	stefan	PROPN
fnp-3528	483	2	,	,	PUNCT
fnp-3528	483	3	k.	k.	PROPN
fnp-3528	483	4	;	;	PUNCT
fnp-3528	483	5	leck	leck	PROPN
fnp-3528	483	6	,	,	PUNCT
fnp-3528	483	7	l.	l.	PROPN
fnp-3528	483	8	y.	y.	PROPN
fnp-3528	483	9	w.	w.	PROPN
fnp-3528	483	10	;	;	PUNCT
fnp-3528	483	11	namasivayam	namasivayam	PROPN
fnp-3528	483	12	,	,	PUNCT
fnp-3528	483	13	v.	v.	ADV
fnp-3528	483	14	;	;	PUNCT
fnp-3528	483	15	bascuñana	bascuñana	PROPN
fnp-3528	483	16	,	,	PUNCT
fnp-3528	483	17	p.	p.	PROPN
fnp-3528	483	18	;	;	PUNCT
fnp-3528	483	19	huang	huang	PROPN
fnp-3528	483	20	,	,	PUNCT
fnp-3528	483	21	m.	m.	NOUN
fnp-3528	483	22	l.-h	l.-h	PROPN
fnp-3528	483	23	.	.	PUNCT
fnp-3528	483	24	;	;	PUNCT
fnp-3528	483	25	riss	riss	PROPN
fnp-3528	483	26	,	,	PUNCT
fnp-3528	483	27	p.	p.	PROPN
fnp-3528	483	28	j.	j.	PROPN
fnp-3528	483	29	;	;	PUNCT
fnp-3528	483	30	pahnke	pahnke	PROPN
fnp-3528	483	31	,	,	PUNCT
fnp-3528	483	32	j.	j.	PROPN
fnp-3528	483	33	;	;	PUNCT
fnp-3528	483	34	jansson	jansson	PROPN
fnp-3528	483	35	,	,	PUNCT
fnp-3528	483	36	p.	p.	PROPN
fnp-3528	483	37	j.	j.	PROPN
fnp-3528	483	38	;	;	PUNCT
fnp-3528	483	39	stefan	stefan	PROPN
fnp-3528	483	40	,	,	PUNCT
fnp-3528	483	41	s.	s.	PROPN
fnp-3528	483	42	m.	m.	PROPN
fnp-3528	483	43	vesicular	vesicular	ADJ
fnp-3528	483	44	atp	atp	PROPN
fnp-3528	483	45	-	-	PUNCT
fnp-3528	483	46	binding	bind	VERB
fnp-3528	483	47	cassette	cassette	NOUN
fnp-3528	483	48	transporters	transporter	NOUN
fnp-3528	483	49	in	in	ADP
fnp-3528	483	50	human	human	ADJ
fnp-3528	483	51	disease	disease	NOUN
fnp-3528	483	52	:	:	PUNCT
fnp-3528	483	53	relevant	relevant	ADJ
fnp-3528	483	54	aspects	aspect	NOUN
fnp-3528	483	55	of	of	ADP
fnp-3528	483	56	their	their	PRON
fnp-3528	483	57	organization	organization	NOUN
fnp-3528	483	58	for	for	ADP
fnp-3528	483	59	future	future	ADJ
fnp-3528	483	60	drug	drug	NOUN
fnp-3528	483	61	development	development	NOUN
fnp-3528	483	62	.	.	PUNCT
fnp-3528	484	1	future	future	ADJ
fnp-3528	484	2	drug	drug	NOUN
fnp-3528	484	3	discov	discov	NOUN
fnp-3528	484	4	2020	2020	NUM
fnp-3528	484	5	,	,	PUNCT
fnp-3528	484	6	2	2	NUM
fnp-3528	484	7	,	,	PUNCT
fnp-3528	484	8	fdd51	fdd51	PROPN
fnp-3528	484	9	.	.	PUNCT
fnp-3528	484	10	domenichini	domenichini	PROPN
fnp-3528	484	11	,	,	PUNCT
fnp-3528	484	12	a.	a.	NOUN
fnp-3528	484	13	;	;	PUNCT
fnp-3528	484	14	adamska	adamska	PROPN
fnp-3528	484	15	,	,	PUNCT
fnp-3528	484	16	a.	a.	NOUN
fnp-3528	484	17	;	;	PUNCT
fnp-3528	484	18	falasca	falasca	PROPN
fnp-3528	484	19	,	,	PUNCT
fnp-3528	484	20	m.	m.	NOUN
fnp-3528	484	21	abc	abc	PROPN
fnp-3528	484	22	transporters	transporter	NOUN
fnp-3528	484	23	as	as	ADP
fnp-3528	484	24	cancer	cancer	NOUN
fnp-3528	484	25	drivers	driver	NOUN
fnp-3528	484	26	:	:	PUNCT
fnp-3528	484	27	potential	potential	ADJ
fnp-3528	484	28	functions	function	NOUN
fnp-3528	484	29	in	in	ADP
fnp-3528	484	30	cancer	cancer	NOUN
fnp-3528	484	31	development	development	NOUN
fnp-3528	484	32	.	.	PUNCT
fnp-3528	485	1	biochim	biochim	PROPN
fnp-3528	485	2	biophys	biophy	NOUN
fnp-3528	485	3	acta	acta	PROPN
fnp-3528	485	4	gen	gen	PROPN
fnp-3528	485	5	subj	subj	PROPN
fnp-3528	485	6	2019	2019	NUM
fnp-3528	485	7	,	,	PUNCT
fnp-3528	485	8	1863	1863	NUM
fnp-3528	485	9	,	,	PUNCT
fnp-3528	485	10	52	52	NUM
fnp-3528	485	11	-	-	SYM
fnp-3528	485	12	60	60	NUM
fnp-3528	485	13	.	.	PUNCT
fnp-3528	486	1	adamska	adamska	PROPN
fnp-3528	486	2	,	,	PUNCT
fnp-3528	486	3	a.	a.	NOUN
fnp-3528	486	4	;	;	PUNCT
fnp-3528	486	5	falasca	falasca	PROPN
fnp-3528	486	6	,	,	PUNCT
fnp-3528	486	7	m.	m.	PROPN
fnp-3528	486	8	atp	atp	PROPN
fnp-3528	486	9	-	-	PUNCT
fnp-3528	486	10	binding	bind	VERB
fnp-3528	486	11	cassette	cassette	NOUN
fnp-3528	486	12	transporters	transporter	NOUN
fnp-3528	486	13	in	in	ADP
fnp-3528	486	14	progression	progression	NOUN
fnp-3528	486	15	and	and	CCONJ
fnp-3528	486	16	clinical	clinical	ADJ
fnp-3528	486	17	outcome	outcome	NOUN
fnp-3528	486	18	of	of	ADP
fnp-3528	486	19	pancreatic	pancreatic	ADJ
fnp-3528	486	20	cancer	cancer	NOUN
fnp-3528	486	21	:	:	PUNCT
fnp-3528	486	22	what	what	PRON
fnp-3528	486	23	is	be	AUX
fnp-3528	486	24	the	the	DET
fnp-3528	486	25	way	way	NOUN
fnp-3528	486	26	forward	forward	ADV
fnp-3528	486	27	?	?	PUNCT
fnp-3528	487	1	world	world	PROPN
fnp-3528	487	2	j	j	PROPN
fnp-3528	487	3	gastroenterol	gastroenterol	PROPN
fnp-3528	487	4	2018	2018	NUM
fnp-3528	487	5	,	,	PUNCT
fnp-3528	487	6	24	24	NUM
fnp-3528	487	7	,	,	PUNCT
fnp-3528	487	8	3222	3222	NUM
fnp-3528	487	9	-	-	SYM
fnp-3528	487	10	38	38	NUM
fnp-3528	487	11	.	.	PUNCT
fnp-3528	488	1	robey	robey	PROPN
fnp-3528	488	2	,	,	PUNCT
fnp-3528	488	3	r.	r.	PROPN
fnp-3528	488	4	w.	w.	PROPN
fnp-3528	488	5	;	;	PUNCT
fnp-3528	488	6	pluchino	pluchino	PROPN
fnp-3528	488	7	,	,	PUNCT
fnp-3528	488	8	k.	k.	PROPN
fnp-3528	488	9	m.	m.	PROPN
fnp-3528	488	10	;	;	PUNCT
fnp-3528	488	11	hall	hall	PROPN
fnp-3528	488	12	,	,	PUNCT
fnp-3528	488	13	m.	m.	NOUN
fnp-3528	488	14	d.	d.	PROPN
fnp-3528	488	15	;	;	PUNCT
fnp-3528	488	16	fojo	fojo	NOUN
fnp-3528	488	17	,	,	PUNCT
fnp-3528	488	18	a.	a.	NOUN
fnp-3528	488	19	t.	t.	PROPN
fnp-3528	488	20	;	;	PUNCT
fnp-3528	488	21	bates	bate	NOUN
fnp-3528	488	22	,	,	PUNCT
fnp-3528	488	23	s.	s.	PROPN
fnp-3528	488	24	e.	e.	PROPN
fnp-3528	488	25	;	;	PUNCT
fnp-3528	488	26	gottesman	gottesman	NOUN
fnp-3528	488	27	,	,	PUNCT
fnp-3528	488	28	m.	m.	NOUN
fnp-3528	488	29	m.	m.	NOUN
fnp-3528	488	30	revisiting	revisit	VERB
fnp-3528	488	31	the	the	DET
fnp-3528	488	32	role	role	NOUN
fnp-3528	488	33	of	of	ADP
fnp-3528	488	34	abc	abc	PROPN
fnp-3528	488	35	transporters	transporter	NOUN
fnp-3528	488	36	in	in	ADP
fnp-3528	488	37	multidrug	multidrug	NOUN
fnp-3528	488	38	-	-	PUNCT
fnp-3528	488	39	resistant	resistant	ADJ
fnp-3528	488	40	cancer	cancer	NOUN
fnp-3528	488	41	.	.	PUNCT
fnp-3528	489	1	nat	nat	PROPN
fnp-3528	489	2	rev	rev	VERB
fnp-3528	489	3	cancer	cancer	NOUN
fnp-3528	489	4	2018	2018	NUM
fnp-3528	489	5	,	,	PUNCT
fnp-3528	489	6	18	18	NUM
fnp-3528	489	7	,	,	PUNCT
fnp-3528	489	8	452	452	NUM
fnp-3528	489	9	-	-	SYM
fnp-3528	489	10	64	64	NUM
fnp-3528	489	11	.	.	PUNCT
fnp-3528	490	1	sasaki	sasaki	PROPN
fnp-3528	490	2	,	,	PUNCT
fnp-3528	490	3	k.	k.	PROPN
fnp-3528	490	4	;	;	PUNCT
fnp-3528	490	5	tachikawa	tachikawa	PROPN
fnp-3528	490	6	,	,	PUNCT
fnp-3528	490	7	m.	m.	NOUN
fnp-3528	490	8	;	;	PUNCT
fnp-3528	490	9	uchida	uchida	PROPN
fnp-3528	490	10	,	,	PUNCT
fnp-3528	490	11	y.	y.	PROPN
fnp-3528	490	12	;	;	PUNCT
fnp-3528	490	13	hirano	hirano	PROPN
fnp-3528	490	14	,	,	PUNCT
fnp-3528	490	15	s.	s.	PROPN
fnp-3528	490	16	;	;	PUNCT
fnp-3528	490	17	kadowaki	kadowaki	PROPN
fnp-3528	490	18	,	,	PUNCT
fnp-3528	490	19	f.	f.	PROPN
fnp-3528	490	20	;	;	PUNCT
fnp-3528	490	21	watanabe	watanabe	PROPN
fnp-3528	490	22	,	,	PUNCT
fnp-3528	490	23	m.	m.	NOUN
fnp-3528	490	24	;	;	PUNCT
fnp-3528	490	25	ohtsuki	ohtsuki	PROPN
fnp-3528	490	26	,	,	PUNCT
fnp-3528	490	27	s.	s.	PROPN
fnp-3528	490	28	;	;	PUNCT
fnp-3528	490	29	terasaki	terasaki	PROPN
fnp-3528	490	30	,	,	PUNCT
fnp-3528	490	31	t.	t.	PROPN
fnp-3528	490	32	atp	atp	PROPN
fnp-3528	490	33	-	-	PUNCT
fnp-3528	490	34	binding	bind	VERB
fnp-3528	490	35	cassette	cassette	NOUN
fnp-3528	490	36	transporter	transporter	VERB
fnp-3528	490	37	a	a	DET
fnp-3528	490	38	subfamily	subfamily	ADV
fnp-3528	490	39	8	8	NUM
fnp-3528	490	40	is	be	AUX
fnp-3528	490	41	a	a	DET
fnp-3528	490	42	sinusoidal	sinusoidal	ADJ
fnp-3528	490	43	efflux	efflux	NOUN
fnp-3528	490	44	transporter	transporter	NOUN
fnp-3528	490	45	for	for	ADP
fnp-3528	490	46	cholesterol	cholesterol	NOUN
fnp-3528	490	47	and	and	CCONJ
fnp-3528	490	48	taurocholate	taurocholate	NOUN
fnp-3528	490	49	in	in	ADP
fnp-3528	490	50	mouse	mouse	NOUN
fnp-3528	490	51	and	and	CCONJ
fnp-3528	490	52	human	human	ADJ
fnp-3528	490	53	liver	liver	NOUN
fnp-3528	490	54	.	.	PUNCT
fnp-3528	491	1	mol	mol	ADP
fnp-3528	491	2	pharm	pharm	PROPN
fnp-3528	491	3	2018	2018	NUM
fnp-3528	491	4	,	,	PUNCT
fnp-3528	491	5	15	15	NUM
fnp-3528	491	6	,	,	PUNCT
fnp-3528	491	7	343	343	NUM
fnp-3528	491	8	-	-	SYM
fnp-3528	491	9	55	55	NUM
fnp-3528	491	10	.	.	PUNCT
fnp-3528	492	1	pan	pan	PROPN
fnp-3528	492	2	,	,	PUNCT
fnp-3528	492	3	s.	s.	PROPN
fnp-3528	492	4	t.	t.	PROPN
fnp-3528	492	5	;	;	PUNCT
fnp-3528	492	6	li	li	PROPN
fnp-3528	492	7	,	,	PUNCT
fnp-3528	492	8	z.	z.	PROPN
fnp-3528	492	9	l.	l.	PROPN
fnp-3528	492	10	;	;	PUNCT
fnp-3528	492	11	he	he	PRON
fnp-3528	492	12	,	,	PUNCT
fnp-3528	492	13	z.	z.	PROPN
fnp-3528	492	14	x.	x.	PROPN
fnp-3528	492	15	;	;	PUNCT
fnp-3528	492	16	qiu	qiu	PROPN
fnp-3528	492	17	,	,	PUNCT
fnp-3528	492	18	j.	j.	PROPN
fnp-3528	492	19	x.	x.	PROPN
fnp-3528	492	20	;	;	PUNCT
fnp-3528	492	21	zhou	zhou	PROPN
fnp-3528	492	22	,	,	PUNCT
fnp-3528	493	1	s.	s.	PROPN
fnp-3528	493	2	f.	f.	PROPN
fnp-3528	493	3	molecular	molecular	ADJ
fnp-3528	493	4	mechanisms	mechanism	NOUN
fnp-3528	493	5	for	for	ADP
fnp-3528	493	6	tumour	tumour	PRON
fnp-3528	493	7	resistance	resistance	NOUN
fnp-3528	493	8	to	to	ADP
fnp-3528	493	9	chemotherapy	chemotherapy	NOUN
fnp-3528	493	10	.	.	PUNCT
fnp-3528	494	1	clin	clin	PROPN
fnp-3528	494	2	exp	exp	PROPN
fnp-3528	494	3	pharmacol	pharmacol	PROPN
fnp-3528	494	4	physiol	physiol	PROPN
fnp-3528	494	5	2016	2016	NUM
fnp-3528	494	6	,	,	PUNCT
fnp-3528	494	7	43	43	NUM
fnp-3528	494	8	,	,	PUNCT
fnp-3528	494	9	723	723	NUM
fnp-3528	494	10	-	-	SYM
fnp-3528	494	11	37	37	NUM
fnp-3528	494	12	.	.	PUNCT
fnp-3528	494	13	ween	ween	NOUN
fnp-3528	494	14	,	,	PUNCT
fnp-3528	494	15	m.	m.	NOUN
fnp-3528	494	16	p.	p.	PROPN
fnp-3528	494	17	;	;	PUNCT
fnp-3528	494	18	armstrong	armstrong	PROPN
fnp-3528	494	19	,	,	PUNCT
fnp-3528	494	20	m.	m.	NOUN
fnp-3528	494	21	a.	a.	PROPN
fnp-3528	494	22	;	;	PUNCT
fnp-3528	494	23	oehler	oehler	NOUN
fnp-3528	494	24	,	,	PUNCT
fnp-3528	494	25	m.	m.	PROPN
fnp-3528	494	26	k.	k.	PROPN
fnp-3528	494	27	;	;	PUNCT
fnp-3528	494	28	ricciardelli	ricciardelli	PROPN
fnp-3528	494	29	,	,	PUNCT
fnp-3528	494	30	c.	c.	NOUN
fnp-3528	494	31	the	the	DET
fnp-3528	494	32	role	role	NOUN
fnp-3528	494	33	of	of	ADP
fnp-3528	494	34	abc	abc	PROPN
fnp-3528	494	35	transporters	transporter	NOUN
fnp-3528	494	36	in	in	ADP
fnp-3528	494	37	ovarian	ovarian	ADJ
fnp-3528	494	38	cancer	cancer	NOUN
fnp-3528	494	39	progression	progression	NOUN
fnp-3528	494	40	and	and	CCONJ
fnp-3528	494	41	chemoresistance	chemoresistance	NOUN
fnp-3528	494	42	.	.	PUNCT
fnp-3528	495	1	crit	crit	PROPN
fnp-3528	495	2	rev	rev	PROPN
fnp-3528	495	3	oncol	oncol	ADJ
fnp-3528	495	4	hematol	hematol	NOUN
fnp-3528	495	5	2015	2015	NUM
fnp-3528	495	6	,	,	PUNCT
fnp-3528	495	7	96	96	NUM
fnp-3528	495	8	,	,	PUNCT
fnp-3528	495	9	220	220	NUM
fnp-3528	495	10	-	-	SYM
fnp-3528	495	11	56	56	NUM
fnp-3528	495	12	.	.	PUNCT
fnp-3528	495	13	wenzel	wenzel	PROPN
fnp-3528	495	14	,	,	PUNCT
fnp-3528	495	15	j.	j.	PROPN
fnp-3528	495	16	j.	j.	PROPN
fnp-3528	495	17	;	;	PUNCT
fnp-3528	495	18	piehler	piehler	PROPN
fnp-3528	495	19	,	,	PUNCT
fnp-3528	495	20	a.	a.	NOUN
fnp-3528	495	21	;	;	PUNCT
fnp-3528	496	1	kaminski	kaminski	PROPN
fnp-3528	496	2	,	,	PUNCT
fnp-3528	496	3	w.	w.	PROPN
fnp-3528	496	4	e.	e.	PROPN
fnp-3528	496	5	abc	abc	PROPN
fnp-3528	496	6	a	a	DET
fnp-3528	496	7	-	-	PUNCT
fnp-3528	496	8	subclass	subclass	NOUN
fnp-3528	496	9	proteins	protein	NOUN
fnp-3528	496	10	:	:	PUNCT
fnp-3528	496	11	gatekeepers	gatekeeper	NOUN
fnp-3528	496	12	of	of	ADP
fnp-3528	496	13	cellular	cellular	ADJ
fnp-3528	496	14	phosphoand	phosphoand	NOUN
fnp-3528	496	15	sphingolipid	sphingolipid	PROPN
fnp-3528	496	16	transport	transport	PROPN
fnp-3528	496	17	.	.	PUNCT
fnp-3528	497	1	front	front	ADJ
fnp-3528	497	2	biosci	biosci	PROPN
fnp-3528	497	3	2007	2007	NUM
fnp-3528	497	4	,	,	PUNCT
fnp-3528	497	5	12	12	NUM
fnp-3528	497	6	,	,	PUNCT
fnp-3528	497	7	3177	3177	NUM
fnp-3528	497	8	-	-	SYM
fnp-3528	497	9	93	93	NUM
fnp-3528	497	10	.	.	PUNCT
fnp-3528	498	1	stefan	stefan	PROPN
fnp-3528	498	2	,	,	PUNCT
fnp-3528	498	3	s.	s.	PROPN
fnp-3528	498	4	m.	m.	PROPN
fnp-3528	498	5	multi	multi	PROPN
fnp-3528	498	6	-	-	ADJ
fnp-3528	498	7	target	target	ADJ
fnp-3528	498	8	abc	abc	NOUN
fnp-3528	498	9	transporter	transporter	NOUN
fnp-3528	498	10	modulators	modulator	NOUN
fnp-3528	498	11	:	:	PUNCT
fnp-3528	498	12	what	what	PRON
fnp-3528	498	13	next	next	ADJ
fnp-3528	498	14	and	and	CCONJ
fnp-3528	498	15	where	where	SCONJ
fnp-3528	498	16	to	to	PART
fnp-3528	498	17	go	go	VERB
fnp-3528	498	18	?	?	PUNCT
fnp-3528	499	1	future	future	ADJ
fnp-3528	499	2	med	med	ADJ
fnp-3528	499	3	chem	chem	NOUN
fnp-3528	499	4	2019	2019	NUM
fnp-3528	499	5	,	,	PUNCT
fnp-3528	499	6	11	11	NUM
fnp-3528	499	7	,	,	PUNCT
fnp-3528	499	8	2353	2353	NUM
fnp-3528	499	9	-	-	SYM
fnp-3528	499	10	58	58	NUM
fnp-3528	499	11	.	.	PUNCT
fnp-3528	500	1	yu	yu	PROPN
fnp-3528	500	2	,	,	PUNCT
fnp-3528	500	3	m.	m.	NOUN
fnp-3528	500	4	;	;	PUNCT
fnp-3528	500	5	ocana	ocana	PROPN
fnp-3528	500	6	,	,	PUNCT
fnp-3528	500	7	a.	a.	NOUN
fnp-3528	500	8	;	;	PUNCT
fnp-3528	500	9	tannock	tannock	NOUN
fnp-3528	500	10	,	,	PUNCT
fnp-3528	500	11	i.	i.	PROPN
fnp-3528	500	12	f.	f.	PROPN
fnp-3528	500	13	reversal	reversal	PROPN
fnp-3528	500	14	of	of	ADP
fnp-3528	500	15	atp	atp	NOUN
fnp-3528	500	16	-	-	PUNCT
fnp-3528	500	17	binding	bind	VERB
fnp-3528	500	18	cassette	cassette	NOUN
fnp-3528	500	19	drug	drug	NOUN
fnp-3528	500	20	transporter	transporter	NOUN
fnp-3528	500	21	activity	activity	NOUN
fnp-3528	500	22	to	to	PART
fnp-3528	500	23	modulate	modulate	VERB
fnp-3528	500	24	chemoresistance	chemoresistance	NOUN
fnp-3528	500	25	:	:	PUNCT
fnp-3528	500	26	why	why	SCONJ
fnp-3528	500	27	has	have	AUX
fnp-3528	500	28	it	it	PRON
fnp-3528	500	29	failed	fail	VERB
fnp-3528	500	30	to	to	PART
fnp-3528	500	31	provide	provide	VERB
fnp-3528	500	32	clinical	clinical	ADJ
fnp-3528	500	33	benefit	benefit	NOUN
fnp-3528	500	34	?	?	PUNCT
fnp-3528	501	1	cancer	cancer	NOUN
fnp-3528	501	2	metastasis	metastasis	NOUN
fnp-3528	501	3	rev	rev	VERB
fnp-3528	501	4	2013	2013	NUM
fnp-3528	501	5	,	,	PUNCT
fnp-3528	501	6	32	32	NUM
fnp-3528	501	7	,	,	PUNCT
fnp-3528	501	8	211	211	NUM
fnp-3528	501	9	-	-	SYM
fnp-3528	501	10	27	27	NUM
fnp-3528	501	11	.	.	PUNCT
fnp-3528	502	1	amiri	amiri	PROPN
fnp-3528	502	2	-	-	PUNCT
fnp-3528	502	3	kordestani	kordestani	PROPN
fnp-3528	502	4	,	,	PUNCT
fnp-3528	502	5	l.	l.	PROPN
fnp-3528	502	6	;	;	PUNCT
fnp-3528	502	7	basseville	basseville	PROPN
fnp-3528	502	8	,	,	PUNCT
fnp-3528	502	9	a.	a.	NOUN
fnp-3528	502	10	;	;	PUNCT
fnp-3528	502	11	kurdziel	kurdziel	PROPN
fnp-3528	502	12	,	,	PUNCT
fnp-3528	502	13	k.	k.	PROPN
fnp-3528	502	14	;	;	PUNCT
fnp-3528	502	15	fojo	fojo	NOUN
fnp-3528	502	16	,	,	PUNCT
fnp-3528	502	17	a.	a.	NOUN
fnp-3528	502	18	t.	t.	PROPN
fnp-3528	502	19	;	;	PUNCT
fnp-3528	502	20	bates	bate	NOUN
fnp-3528	502	21	,	,	PUNCT
fnp-3528	502	22	s.	s.	PROPN
fnp-3528	502	23	e.	e.	PROPN
fnp-3528	502	24	targeting	target	VERB
fnp-3528	502	25	mdr	mdr	PROPN
fnp-3528	502	26	in	in	ADP
fnp-3528	502	27	breast	breast	NOUN
fnp-3528	502	28	and	and	CCONJ
fnp-3528	502	29	lung	lung	NOUN
fnp-3528	502	30	cancer	cancer	NOUN
fnp-3528	502	31	:	:	PUNCT
fnp-3528	502	32	discriminating	discriminate	VERB
fnp-3528	502	33	its	its	PRON
fnp-3528	502	34	potential	potential	ADJ
fnp-3528	502	35	importance	importance	NOUN
fnp-3528	502	36	from	from	ADP
fnp-3528	502	37	the	the	DET
fnp-3528	502	38	failure	failure	NOUN
fnp-3528	502	39	of	of	ADP
fnp-3528	502	40	drug	drug	NOUN
fnp-3528	502	41	resistance	resistance	NOUN
fnp-3528	502	42	reversal	reversal	NOUN
fnp-3528	502	43	studies	study	NOUN
fnp-3528	502	44	.	.	PUNCT
fnp-3528	503	1	drug	drug	NOUN
fnp-3528	503	2	resist	resist	VERB
fnp-3528	503	3	updat	updat	PROPN
fnp-3528	503	4	2012	2012	NUM
fnp-3528	503	5	,	,	PUNCT
fnp-3528	503	6	15	15	NUM
fnp-3528	503	7	,	,	PUNCT
fnp-3528	503	8	50	50	NUM
fnp-3528	503	9	-	-	SYM
fnp-3528	503	10	61	61	NUM
fnp-3528	503	11	.	.	PUNCT
fnp-3528	504	1	tamaki	tamaki	NOUN
fnp-3528	504	2	,	,	PUNCT
fnp-3528	504	3	a.	a.	NOUN
fnp-3528	504	4	;	;	PUNCT
fnp-3528	504	5	ierano	ierano	PROPN
fnp-3528	504	6	,	,	PUNCT
fnp-3528	504	7	c.	c.	PROPN
fnp-3528	504	8	;	;	PUNCT
fnp-3528	504	9	szakacs	szakacs	PROPN
fnp-3528	504	10	,	,	PUNCT
fnp-3528	504	11	g.	g.	PROPN
fnp-3528	504	12	;	;	PUNCT
fnp-3528	504	13	robey	robey	PROPN
fnp-3528	504	14	,	,	PUNCT
fnp-3528	504	15	r.	r.	PROPN
fnp-3528	504	16	w.	w.	PROPN
fnp-3528	504	17	;	;	PUNCT
fnp-3528	504	18	bates	bates	PROPN
fnp-3528	504	19	,	,	PUNCT
fnp-3528	504	20	s.	s.	PROPN
fnp-3528	504	21	e.	e.	PROPN
fnp-3528	505	1	the	the	DET
fnp-3528	505	2	controversial	controversial	ADJ
fnp-3528	505	3	role	role	NOUN
fnp-3528	505	4	of	of	ADP
fnp-3528	505	5	abc	abc	PROPN
fnp-3528	505	6	transporters	transporter	NOUN
fnp-3528	505	7	in	in	ADP
fnp-3528	505	8	clinical	clinical	ADJ
fnp-3528	505	9	oncology	oncology	NOUN
fnp-3528	505	10	.	.	PUNCT
fnp-3528	506	1	essays	essays	PROPN
fnp-3528	506	2	biochem	biochem	PROPN
fnp-3528	506	3	2011	2011	NUM
fnp-3528	506	4	,	,	PUNCT
fnp-3528	506	5	50	50	NUM
fnp-3528	506	6	,	,	PUNCT
fnp-3528	506	7	209	209	NUM
fnp-3528	506	8	-	-	SYM
fnp-3528	506	9	32	32	NUM
fnp-3528	506	10	.	.	PUNCT
fnp-3528	507	1	namasivayam	namasivayam	PROPN
fnp-3528	507	2	,	,	PUNCT
fnp-3528	507	3	v.	v.	ADV
fnp-3528	507	4	;	;	PUNCT
fnp-3528	507	5	silbermann	silbermann	NOUN
fnp-3528	507	6	,	,	PUNCT
fnp-3528	507	7	k.	k.	PROPN
fnp-3528	507	8	;	;	PUNCT
fnp-3528	507	9	pahnke	pahnke	PROPN
fnp-3528	507	10	,	,	PUNCT
fnp-3528	507	11	j.	j.	PROPN
fnp-3528	507	12	;	;	PUNCT
fnp-3528	507	13	wiese	wiese	PROPN
fnp-3528	507	14	,	,	PUNCT
fnp-3528	507	15	m.	m.	NOUN
fnp-3528	507	16	;	;	PUNCT
fnp-3528	507	17	stefan	stefan	PROPN
fnp-3528	507	18	,	,	PUNCT
fnp-3528	508	1	s.	s.	PROPN
fnp-3528	508	2	m.	m.	PROPN
fnp-3528	508	3	scaffold	scaffold	NOUN
fnp-3528	508	4	fragmentation	fragmentation	NOUN
fnp-3528	508	5	and	and	CCONJ
fnp-3528	508	6	substructure	substructure	NOUN
fnp-3528	508	7	hopping	hop	VERB
fnp-3528	508	8	reveal	reveal	NOUN
fnp-3528	508	9	potential	potential	NOUN
fnp-3528	508	10	,	,	PUNCT
fnp-3528	508	11	robustness	robustness	NOUN
fnp-3528	508	12	,	,	PUNCT
fnp-3528	508	13	and	and	CCONJ
fnp-3528	508	14	limits	limit	NOUN
fnp-3528	508	15	of	of	ADP
fnp-3528	508	16	computer	computer	NOUN
fnp-3528	508	17	-	-	PUNCT
fnp-3528	508	18	aided	aid	VERB
fnp-3528	508	19	pattern	pattern	NOUN
fnp-3528	508	20	analysis	analysis	NOUN
fnp-3528	508	21	(	(	PUNCT
fnp-3528	508	22	c@pa	c@pa	NOUN
fnp-3528	508	23	)	)	PUNCT
fnp-3528	508	24	.	.	PUNCT
fnp-3528	509	1	comput	comput	PROPN
fnp-3528	509	2	struct	struct	VERB
fnp-3528	509	3	biotechnol	biotechnol	ADJ
fnp-3528	509	4	j	j	PROPN
fnp-3528	509	5	2021	2021	NUM
fnp-3528	509	6	,	,	PUNCT
fnp-3528	509	7	19	19	NUM
fnp-3528	509	8	,	,	PUNCT
fnp-3528	509	9	3269	3269	NUM
fnp-3528	509	10	-	-	SYM
fnp-3528	509	11	83	83	NUM
fnp-3528	509	12	.	.	PUNCT
fnp-3528	510	1	namasivayam	namasivayam	PROPN
fnp-3528	510	2	,	,	PUNCT
fnp-3528	510	3	v.	v.	ADV
fnp-3528	510	4	;	;	PUNCT
fnp-3528	510	5	silbermann	silbermann	NOUN
fnp-3528	510	6	,	,	PUNCT
fnp-3528	510	7	k.	k.	PROPN
fnp-3528	510	8	;	;	PUNCT
fnp-3528	510	9	wiese	wiese	PROPN
fnp-3528	510	10	,	,	PUNCT
fnp-3528	510	11	m.	m.	NOUN
fnp-3528	510	12	;	;	PUNCT
fnp-3528	510	13	pahnke	pahnke	PROPN
fnp-3528	510	14	,	,	PUNCT
fnp-3528	510	15	j.	j.	PROPN
fnp-3528	510	16	;	;	PUNCT
fnp-3528	510	17	stefan	stefan	PROPN
fnp-3528	510	18	,	,	PUNCT
fnp-3528	510	19	s.	s.	PROPN
fnp-3528	510	20	m.	m.	PROPN
fnp-3528	510	21	c@pa	c@pa	NOUN
fnp-3528	510	22	:	:	PUNCT
fnp-3528	510	23	computer	computer	NOUN
fnp-3528	510	24	-	-	PUNCT
fnp-3528	510	25	aided	aid	VERB
fnp-3528	510	26	pattern	pattern	NOUN
fnp-3528	510	27	analysis	analysis	NOUN
fnp-3528	510	28	to	to	PART
fnp-3528	510	29	predict	predict	VERB
fnp-3528	510	30	multitarget	multitarget	PROPN
fnp-3528	510	31	abc	abc	PROPN
fnp-3528	510	32	transporter	transporter	NOUN
fnp-3528	510	33	inhibitors	inhibitor	NOUN
fnp-3528	510	34	.	.	PUNCT
fnp-3528	511	1	j	j	PROPN
fnp-3528	511	2	med	med	PROPN
fnp-3528	511	3	chem	chem	NOUN
fnp-3528	511	4	2021	2021	NUM
fnp-3528	511	5	,	,	PUNCT
fnp-3528	511	6	64	64	NUM
fnp-3528	511	7	,	,	PUNCT
fnp-3528	511	8	3350	3350	NUM
fnp-3528	511	9	-	-	SYM
fnp-3528	511	10	66	66	NUM
fnp-3528	511	11	.	.	PUNCT
fnp-3528	512	1	zhang	zhang	PROPN
fnp-3528	512	2	,	,	PUNCT
fnp-3528	512	3	h.	h.	PROPN
fnp-3528	512	4	;	;	PUNCT
fnp-3528	512	5	xu	xu	PROPN
fnp-3528	512	6	,	,	PUNCT
fnp-3528	512	7	h.	h.	PROPN
fnp-3528	512	8	;	;	PUNCT
fnp-3528	512	9	ashby	ashby	PROPN
fnp-3528	512	10	,	,	PUNCT
fnp-3528	512	11	c.	c.	PROPN
fnp-3528	512	12	r.	r.	PROPN
fnp-3528	512	13	,	,	PUNCT
fnp-3528	512	14	jr	jr	PROPN
fnp-3528	512	15	.	.	PROPN
fnp-3528	512	16	;	;	PUNCT
fnp-3528	512	17	assaraf	assaraf	NOUN
fnp-3528	512	18	,	,	PUNCT
fnp-3528	512	19	y.	y.	PROPN
fnp-3528	512	20	g.	g.	PROPN
fnp-3528	512	21	;	;	PUNCT
fnp-3528	512	22	chen	chen	PROPN
fnp-3528	512	23	,	,	PUNCT
fnp-3528	512	24	z.	z.	PROPN
fnp-3528	512	25	s.	s.	PROPN
fnp-3528	512	26	;	;	PUNCT
fnp-3528	512	27	liu	liu	PROPN
fnp-3528	512	28	,	,	PUNCT
fnp-3528	512	29	h.	h.	PROPN
fnp-3528	512	30	m.	m.	PROPN
fnp-3528	512	31	chemical	chemical	PROPN
fnp-3528	512	32	molecular	molecular	NOUN
fnp-3528	512	33	-	-	PUNCT
fnp-3528	512	34	based	base	VERB
fnp-3528	512	35	approach	approach	NOUN
fnp-3528	512	36	to	to	PART
fnp-3528	512	37	overcome	overcome	VERB
fnp-3528	512	38	multidrug	multidrug	NOUN
fnp-3528	512	39	resistance	resistance	NOUN
fnp-3528	512	40	in	in	ADP
fnp-3528	512	41	cancer	cancer	NOUN
fnp-3528	512	42	by	by	ADP
fnp-3528	512	43	targeting	target	VERB
fnp-3528	512	44	p	p	NOUN
fnp-3528	512	45	-	-	PUNCT
fnp-3528	512	46	glycoprotein	glycoprotein	NOUN
fnp-3528	512	47	(	(	PUNCT
fnp-3528	512	48	p	p	NOUN
fnp-3528	512	49	-	-	PUNCT
fnp-3528	512	50	gp	gp	NOUN
fnp-3528	512	51	)	)	PUNCT
fnp-3528	512	52	.	.	PUNCT
fnp-3528	513	1	med	med	PROPN
fnp-3528	513	2	res	re	NOUN
fnp-3528	513	3	rev	rev	X
fnp-3528	513	4	2021	2021	NUM
fnp-3528	513	5	,	,	PUNCT
fnp-3528	513	6	41	41	NUM
fnp-3528	513	7	,	,	PUNCT
fnp-3528	513	8	525	525	NUM
fnp-3528	513	9	-	-	SYM
fnp-3528	513	10	55	55	NUM
fnp-3528	513	11	.	.	PUNCT
fnp-3528	514	1	dong	dong	PROPN
fnp-3528	514	2	,	,	PUNCT
fnp-3528	514	3	j.	j.	PROPN
fnp-3528	514	4	;	;	PUNCT
fnp-3528	514	5	qin	qin	PROPN
fnp-3528	514	6	,	,	PUNCT
fnp-3528	514	7	z.	z.	PROPN
fnp-3528	514	8	;	;	PUNCT
fnp-3528	514	9	zhang	zhang	PROPN
fnp-3528	514	10	,	,	PUNCT
fnp-3528	514	11	w.	w.	PROPN
fnp-3528	514	12	d.	d.	PROPN
fnp-3528	514	13	;	;	PUNCT
fnp-3528	514	14	cheng	cheng	PROPN
fnp-3528	514	15	,	,	PUNCT
fnp-3528	514	16	g.	g.	PROPN
fnp-3528	514	17	;	;	PUNCT
fnp-3528	514	18	yehuda	yehuda	NOUN
fnp-3528	514	19	,	,	PUNCT
fnp-3528	514	20	a.	a.	NOUN
fnp-3528	514	21	g.	g.	PROPN
fnp-3528	514	22	;	;	PUNCT
fnp-3528	514	23	ashby	ashby	PROPN
fnp-3528	514	24	,	,	PUNCT
fnp-3528	514	25	c.	c.	PROPN
fnp-3528	514	26	r.	r.	PROPN
fnp-3528	514	27	,	,	PUNCT
fnp-3528	514	28	jr	jr	PROPN
fnp-3528	514	29	.	.	PROPN
fnp-3528	514	30	;	;	PUNCT
fnp-3528	514	31	chen	chen	PROPN
fnp-3528	514	32	,	,	PUNCT
fnp-3528	514	33	z.	z.	PROPN
fnp-3528	514	34	s.	s.	PROPN
fnp-3528	514	35	;	;	PUNCT
fnp-3528	514	36	cheng	cheng	PROPN
fnp-3528	514	37	,	,	PUNCT
fnp-3528	514	38	x.	x.	PROPN
fnp-3528	514	39	d.	d.	PROPN
fnp-3528	514	40	;	;	PUNCT
fnp-3528	514	41	qin	qin	PROPN
fnp-3528	514	42	,	,	PUNCT
fnp-3528	514	43	j.	j.	PROPN
fnp-3528	514	44	j.	j.	PROPN
fnp-3528	514	45	medicinal	medicinal	PROPN
fnp-3528	514	46	chemistry	chemistry	NOUN
fnp-3528	514	47	strategies	strategy	NOUN
fnp-3528	514	48	to	to	PART
fnp-3528	514	49	discover	discover	VERB
fnp-3528	514	50	p	p	NOUN
fnp-3528	514	51	-	-	PUNCT
fnp-3528	514	52	glycoprotein	glycoprotein	ADJ
fnp-3528	514	53	inhibitors	inhibitor	NOUN
fnp-3528	514	54	:	:	PUNCT
fnp-3528	514	55	an	an	DET
fnp-3528	514	56	update	update	NOUN
fnp-3528	514	57	.	.	PUNCT
fnp-3528	515	1	drug	drug	NOUN
fnp-3528	515	2	resist	resist	VERB
fnp-3528	515	3	updat	updat	PROPN
fnp-3528	515	4	2020	2020	NUM
fnp-3528	515	5	,	,	PUNCT
fnp-3528	515	6	49	49	NUM
fnp-3528	515	7	,	,	PUNCT
fnp-3528	515	8	100681	100681	NUM
fnp-3528	515	9	.	.	PUNCT
fnp-3528	516	1	palmeira	palmeira	PROPN
fnp-3528	516	2	,	,	PUNCT
fnp-3528	516	3	a.	a.	PROPN
fnp-3528	516	4	;	;	PUNCT
fnp-3528	516	5	sousa	sousa	PROPN
fnp-3528	516	6	,	,	PUNCT
fnp-3528	516	7	e.	e.	PROPN
fnp-3528	516	8	;	;	PUNCT
fnp-3528	516	9	vasconcelos	vasconcelos	PROPN
fnp-3528	516	10	,	,	PUNCT
fnp-3528	516	11	m.	m.	PROPN
fnp-3528	516	12	h.	h.	PROPN
fnp-3528	516	13	;	;	PUNCT
fnp-3528	516	14	pinto	pinto	NOUN
fnp-3528	516	15	,	,	PUNCT
fnp-3528	516	16	m.	m.	NOUN
fnp-3528	516	17	m.	m.	NOUN
fnp-3528	516	18	three	three	NUM
fnp-3528	516	19	decades	decade	NOUN
fnp-3528	516	20	of	of	ADP
fnp-3528	516	21	p	p	NOUN
fnp-3528	516	22	-	-	PUNCT
fnp-3528	516	23	gp	gp	NOUN
fnp-3528	516	24	inhibitors	inhibitor	NOUN
fnp-3528	516	25	:	:	PUNCT
fnp-3528	516	26	skimming	skim	VERB
fnp-3528	516	27	through	through	ADP
fnp-3528	516	28	several	several	ADJ
fnp-3528	516	29	generations	generation	NOUN
fnp-3528	516	30	and	and	CCONJ
fnp-3528	516	31	scaffolds	scaffold	NOUN
fnp-3528	516	32	.	.	PUNCT
fnp-3528	517	1	curr	curr	PROPN
fnp-3528	517	2	med	med	PROPN
fnp-3528	517	3	chem	chem	NOUN
fnp-3528	517	4	2012	2012	NUM
fnp-3528	517	5	,	,	PUNCT
fnp-3528	517	6	19	19	NUM
fnp-3528	517	7	,	,	PUNCT
fnp-3528	517	8	1946	1946	NUM
fnp-3528	517	9	-	-	SYM
fnp-3528	517	10	2025	2025	NUM
fnp-3528	517	11	.	.	PUNCT
fnp-3528	518	1	wiese	wiese	PROPN
fnp-3528	518	2	,	,	PUNCT
fnp-3528	518	3	m.	m.	NOUN
fnp-3528	518	4	;	;	PUNCT
fnp-3528	518	5	stefan	stefan	PROPN
fnp-3528	518	6	,	,	PUNCT
fnp-3528	518	7	s.	s.	PROPN
fnp-3528	518	8	m.	m.	VERB
fnp-3528	518	9	the	the	DET
fnp-3528	518	10	a	a	PROPN
fnp-3528	518	11	-	-	PUNCT
fnp-3528	518	12	b	b	NOUN
fnp-3528	518	13	-	-	PUNCT
fnp-3528	518	14	c	c	NOUN
fnp-3528	518	15	of	of	ADP
fnp-3528	518	16	small	small	ADJ
fnp-3528	518	17	-	-	PUNCT
fnp-3528	518	18	molecule	molecule	NOUN
fnp-3528	518	19	abc	abc	NOUN
fnp-3528	518	20	transport	transport	NOUN
fnp-3528	518	21	protein	protein	NOUN
fnp-3528	518	22	modulators	modulator	NOUN
fnp-3528	518	23	:	:	PUNCT
fnp-3528	518	24	from	from	ADP
fnp-3528	518	25	inhibition	inhibition	NOUN
fnp-3528	518	26	to	to	ADP
fnp-3528	518	27	activation	activation	NOUN
fnp-3528	518	28	-	-	PUNCT
fnp-3528	518	29	a	a	DET
fnp-3528	518	30	case	case	NOUN
fnp-3528	518	31	study	study	NOUN
fnp-3528	518	32	of	of	ADP
fnp-3528	518	33	multidrug	multidrug	NOUN
fnp-3528	518	34	resistance	resistance	NOUN
fnp-3528	518	35	-	-	PUNCT
fnp-3528	518	36	associated	associate	VERB
fnp-3528	518	37	protein	protein	NOUN
fnp-3528	518	38	1	1	NUM
fnp-3528	518	39	(	(	PUNCT
fnp-3528	518	40	abcc1	abcc1	PROPN
fnp-3528	518	41	)	)	PUNCT
fnp-3528	518	42	.	.	PUNCT
fnp-3528	519	1	med	med	PROPN
fnp-3528	519	2	res	re	NOUN
fnp-3528	519	3	rev	rev	VERB
fnp-3528	519	4	2019	2019	NUM
fnp-3528	519	5	,	,	PUNCT
fnp-3528	519	6	39	39	NUM
fnp-3528	519	7	,	,	PUNCT
fnp-3528	519	8	2031	2031	NUM
fnp-3528	519	9	-	-	SYM
fnp-3528	519	10	81	81	NUM
fnp-3528	519	11	.	.	PUNCT
fnp-3528	520	1	stefan	stefan	PROPN
fnp-3528	520	2	,	,	PUNCT
fnp-3528	520	3	s.	s.	PROPN
fnp-3528	520	4	m.	m.	PROPN
fnp-3528	520	5	;	;	PUNCT
fnp-3528	520	6	wiese	wiese	PROPN
fnp-3528	520	7	,	,	PUNCT
fnp-3528	520	8	m.	m.	NOUN
fnp-3528	520	9	small	small	ADJ
fnp-3528	520	10	-	-	PUNCT
fnp-3528	520	11	molecule	molecule	NOUN
fnp-3528	520	12	inhibitors	inhibitor	NOUN
fnp-3528	520	13	of	of	ADP
fnp-3528	520	14	multidrug	multidrug	NOUN
fnp-3528	520	15	resistance	resistance	NOUN
fnp-3528	520	16	-	-	PUNCT
fnp-3528	520	17	associated	associate	VERB
fnp-3528	520	18	protein	protein	NOUN
fnp-3528	520	19	1	1	NUM
fnp-3528	520	20	and	and	CCONJ
fnp-3528	520	21	related	related	ADJ
fnp-3528	520	22	processes	process	NOUN
fnp-3528	520	23	:	:	PUNCT
fnp-3528	520	24	a	a	DET
fnp-3528	520	25	historic	historic	ADJ
fnp-3528	520	26	approach	approach	NOUN
fnp-3528	520	27	and	and	CCONJ
fnp-3528	520	28	recent	recent	ADJ
fnp-3528	520	29	advances	advance	NOUN
fnp-3528	520	30	.	.	PUNCT
fnp-3528	521	1	med	med	PROPN
fnp-3528	521	2	res	re	NOUN
fnp-3528	521	3	rev	rev	VERB
fnp-3528	521	4	2019	2019	NUM
fnp-3528	521	5	,	,	PUNCT
fnp-3528	521	6	39	39	NUM
fnp-3528	521	7	,	,	PUNCT
fnp-3528	521	8	176	176	NUM
fnp-3528	521	9	-	-	SYM
fnp-3528	521	10	264	264	NUM
fnp-3528	521	11	.	.	PUNCT
fnp-3528	522	1	pena	pena	NOUN
fnp-3528	522	2	-	-	PUNCT
fnp-3528	522	3	solorzano	solorzano	PROPN
fnp-3528	522	4	,	,	PUNCT
fnp-3528	522	5	d.	d.	PROPN
fnp-3528	522	6	;	;	PUNCT
fnp-3528	522	7	stark	stark	PROPN
fnp-3528	522	8	,	,	PUNCT
fnp-3528	522	9	s.	s.	PROPN
fnp-3528	522	10	a.	a.	PROPN
fnp-3528	522	11	;	;	PUNCT
fnp-3528	522	12	konig	konig	PROPN
fnp-3528	522	13	,	,	PUNCT
fnp-3528	522	14	b.	b.	PROPN
fnp-3528	522	15	;	;	PUNCT
fnp-3528	522	16	sierra	sierra	PROPN
fnp-3528	522	17	,	,	PUNCT
fnp-3528	522	18	c.	c.	PROPN
fnp-3528	522	19	a.	a.	PROPN
fnp-3528	522	20	;	;	PUNCT
fnp-3528	522	21	ochoa	ochoa	PROPN
fnp-3528	522	22	-	-	PUNCT
fnp-3528	522	23	puentes	puentes	PROPN
fnp-3528	522	24	,	,	PUNCT
fnp-3528	522	25	c.	c.	PROPN
fnp-3528	522	26	abcg2	abcg2	PROPN
fnp-3528	522	27	/	/	SYM
fnp-3528	523	1	bcrp	bcrp	ADV
fnp-3528	523	2	:	:	PUNCT
fnp-3528	523	3	specific	specific	ADJ
fnp-3528	523	4	and	and	CCONJ
fnp-3528	523	5	nonspecific	nonspecific	ADJ
fnp-3528	523	6	modulators	modulator	NOUN
fnp-3528	523	7	.	.	PUNCT
fnp-3528	524	1	med	med	ADJ
fnp-3528	524	2	res	re	NOUN
fnp-3528	524	3	rev	rev	VERB
fnp-3528	524	4	2017	2017	NUM
fnp-3528	524	5	,	,	PUNCT
fnp-3528	524	6	37	37	NUM
fnp-3528	524	7	,	,	PUNCT
fnp-3528	524	8	987	987	NUM
fnp-3528	524	9	-	-	SYM
fnp-3528	524	10	1050	1050	NUM
fnp-3528	524	11	.	.	PUNCT
fnp-3528	525	1	zhou	zhou	PROPN
fnp-3528	525	2	,	,	PUNCT
fnp-3528	525	3	s.	s.	PROPN
fnp-3528	525	4	f.	f.	PROPN
fnp-3528	525	5	;	;	PUNCT
fnp-3528	525	6	wang	wang	PROPN
fnp-3528	525	7	,	,	PUNCT
fnp-3528	525	8	l.	l.	PROPN
fnp-3528	525	9	l.	l.	PROPN
fnp-3528	525	10	;	;	PUNCT
fnp-3528	525	11	di	di	PROPN
fnp-3528	525	12	,	,	PUNCT
fnp-3528	525	13	y.	y.	PROPN
fnp-3528	525	14	m.	m.	PROPN
fnp-3528	525	15	;	;	PUNCT
fnp-3528	525	16	xue	xue	PROPN
fnp-3528	525	17	,	,	PUNCT
fnp-3528	525	18	c.	c.	PROPN
fnp-3528	525	19	c.	c.	PROPN
fnp-3528	525	20	;	;	PUNCT
fnp-3528	525	21	duan	duan	PROPN
fnp-3528	525	22	,	,	PUNCT
fnp-3528	525	23	w.	w.	PROPN
fnp-3528	525	24	;	;	PUNCT
fnp-3528	525	25	li	li	PROPN
fnp-3528	525	26	,	,	PUNCT
fnp-3528	525	27	c.	c.	PROPN
fnp-3528	525	28	g.	g.	PROPN
fnp-3528	525	29	;	;	PUNCT
fnp-3528	525	30	li	li	PROPN
fnp-3528	525	31	,	,	PUNCT
fnp-3528	525	32	y.	y.	PROPN
fnp-3528	525	33	substrates	substrate	NOUN
fnp-3528	525	34	and	and	CCONJ
fnp-3528	525	35	inhibitors	inhibitor	NOUN
fnp-3528	525	36	of	of	ADP
fnp-3528	525	37	human	human	ADJ
fnp-3528	525	38	multidrug	multidrug	NOUN
fnp-3528	525	39	resistance	resistance	NOUN
fnp-3528	525	40	associated	associate	VERB
fnp-3528	525	41	proteins	protein	NOUN
fnp-3528	525	42	and	and	CCONJ
fnp-3528	525	43	the	the	DET
fnp-3528	525	44	implications	implication	NOUN
fnp-3528	525	45	in	in	ADP
fnp-3528	525	46	drug	drug	NOUN
fnp-3528	525	47	development	development	NOUN
fnp-3528	525	48	.	.	PUNCT
fnp-3528	526	1	curr	curr	PROPN
fnp-3528	526	2	med	med	PROPN
fnp-3528	526	3	chem	chem	NOUN
fnp-3528	526	4	2008	2008	NUM
fnp-3528	526	5	,	,	PUNCT
fnp-3528	526	6	15	15	NUM
fnp-3528	526	7	,	,	PUNCT
fnp-3528	526	8	1981	1981	NUM
fnp-3528	526	9	-	-	SYM
fnp-3528	526	10	2039	2039	NUM
fnp-3528	526	11	.	.	PUNCT
fnp-3528	527	1	norman	norman	PROPN
fnp-3528	527	2	,	,	PUNCT
fnp-3528	527	3	b.	b.	PROPN
fnp-3528	527	4	h.	h.	PROPN
fnp-3528	527	5	inhibitors	inhibitor	NOUN
fnp-3528	527	6	of	of	ADP
fnp-3528	527	7	mrp1	mrp1	NOUN
fnp-3528	527	8	-	-	PUNCT
fnp-3528	527	9	mediated	mediate	VERB
fnp-3528	527	10	multidrug	multidrug	NOUN
fnp-3528	527	11	resistance	resistance	NOUN
fnp-3528	527	12	.	.	PUNCT
fnp-3528	528	1	drugs	drug	NOUN
fnp-3528	528	2	fut	fut	X
fnp-3528	528	3	1998	1998	NUM
fnp-3528	528	4	,	,	PUNCT
fnp-3528	528	5	23(9	23(9	NUM
fnp-3528	528	6	)	)	PUNCT
fnp-3528	528	7	,	,	PUNCT
fnp-3528	528	8	1001	1001	NUM
fnp-3528	528	9	.	.	PUNCT
fnp-3528	529	1	pereira	pereira	PROPN
fnp-3528	529	2	,	,	PUNCT
fnp-3528	529	3	c.	c.	PROPN
fnp-3528	529	4	d.	d.	PROPN
fnp-3528	529	5	;	;	PUNCT
fnp-3528	529	6	martins	martins	PROPN
fnp-3528	529	7	,	,	PUNCT
fnp-3528	529	8	f.	f.	PROPN
fnp-3528	529	9	;	;	PUNCT
fnp-3528	529	10	wiltfang	wiltfang	PROPN
fnp-3528	529	11	,	,	PUNCT
fnp-3528	529	12	j.	j.	PROPN
fnp-3528	529	13	;	;	PUNCT
fnp-3528	529	14	da	da	PROPN
fnp-3528	529	15	cruz	cruz	PROPN
fnp-3528	529	16	,	,	PUNCT
fnp-3528	529	17	e.	e.	PROPN
fnp-3528	529	18	s.	s.	PROPN
fnp-3528	529	19	o.	o.	PROPN
fnp-3528	529	20	a.	a.	PROPN
fnp-3528	529	21	b.	b.	PROPN
fnp-3528	529	22	;	;	PUNCT
fnp-3528	529	23	rebelo	rebelo	NOUN
fnp-3528	529	24	,	,	PUNCT
fnp-3528	529	25	s.	s.	PROPN
fnp-3528	529	26	abc	abc	PROPN
fnp-3528	529	27	transporters	transporter	NOUN
fnp-3528	529	28	are	be	AUX
fnp-3528	529	29	key	key	ADJ
fnp-3528	529	30	players	player	NOUN
fnp-3528	529	31	in	in	ADP
fnp-3528	529	32	alzheimer	alzheimer	PROPN
fnp-3528	529	33	's	's	PART
fnp-3528	529	34	disease	disease	NOUN
fnp-3528	529	35	.	.	PUNCT
fnp-3528	530	1	j	j	PROPN
fnp-3528	530	2	alzheimers	alzheimers	PROPN
fnp-3528	530	3	dis	dis	PROPN
fnp-3528	530	4	2018	2018	NUM
fnp-3528	530	5	,	,	PUNCT
fnp-3528	530	6	61	61	NUM
fnp-3528	530	7	,	,	PUNCT
fnp-3528	530	8	463	463	NUM
fnp-3528	530	9	-	-	SYM
fnp-3528	530	10	85	85	NUM
fnp-3528	530	11	.	.	PUNCT
fnp-3528	531	1	abuznait	abuznait	PROPN
fnp-3528	531	2	,	,	PUNCT
fnp-3528	531	3	a.	a.	PROPN
fnp-3528	531	4	h.	h.	PROPN
fnp-3528	531	5	;	;	PUNCT
fnp-3528	532	1	kaddoumi	kaddoumi	PROPN
fnp-3528	532	2	,	,	PUNCT
fnp-3528	532	3	a.	a.	NOUN
fnp-3528	532	4	role	role	NOUN
fnp-3528	532	5	of	of	ADP
fnp-3528	532	6	abc	abc	PROPN
fnp-3528	532	7	transporters	transporter	NOUN
fnp-3528	532	8	in	in	ADP
fnp-3528	532	9	the	the	DET
fnp-3528	532	10	pathogenesis	pathogenesis	NOUN
fnp-3528	532	11	of	of	ADP
fnp-3528	532	12	alzheimer	alzheimer	PROPN
fnp-3528	532	13	's	's	PART
fnp-3528	532	14	disease	disease	NOUN
fnp-3528	532	15	.	.	PUNCT
fnp-3528	533	1	acs	acs	PROPN
fnp-3528	533	2	chem	chem	PROPN
fnp-3528	533	3	neurosci	neurosci	PROPN
fnp-3528	533	4	2012	2012	NUM
fnp-3528	533	5	,	,	PUNCT
fnp-3528	533	6	3	3	NUM
fnp-3528	533	7	,	,	PUNCT
fnp-3528	533	8	820	820	NUM
fnp-3528	533	9	-	-	SYM
fnp-3528	533	10	31	31	NUM
fnp-3528	533	11	.	.	PUNCT
fnp-3528	534	1	wolf	wolf	PROPN
fnp-3528	534	2	,	,	PUNCT
fnp-3528	534	3	a.	a.	NOUN
fnp-3528	534	4	;	;	PUNCT
fnp-3528	534	5	bauer	bauer	PROPN
fnp-3528	534	6	,	,	PUNCT
fnp-3528	534	7	b.	b.	PROPN
fnp-3528	534	8	;	;	PUNCT
fnp-3528	534	9	hartz	hartz	PROPN
fnp-3528	534	10	,	,	PUNCT
fnp-3528	534	11	a.	a.	PROPN
fnp-3528	534	12	m.	m.	PROPN
fnp-3528	534	13	abc	abc	PROPN
fnp-3528	534	14	transporters	transporter	NOUN
fnp-3528	534	15	and	and	CCONJ
fnp-3528	534	16	the	the	DET
fnp-3528	534	17	alzheimer	alzheimer	PROPN
fnp-3528	534	18	's	's	PART
fnp-3528	534	19	disease	disease	NOUN
fnp-3528	534	20	enigma	enigma	VERB
fnp-3528	534	21	.	.	PUNCT
fnp-3528	535	1	front	front	ADJ
fnp-3528	535	2	psychiatry	psychiatry	NOUN
fnp-3528	535	3	2012	2012	NUM
fnp-3528	535	4	,	,	PUNCT
fnp-3528	535	5	3	3	NUM
fnp-3528	535	6	,	,	PUNCT
fnp-3528	535	7	54	54	NUM
fnp-3528	535	8	.	.	PUNCT
fnp-3528	536	1	redzic	redzic	PROPN
fnp-3528	536	2	,	,	PUNCT
fnp-3528	536	3	z.	z.	PROPN
fnp-3528	536	4	molecular	molecular	ADJ
fnp-3528	536	5	biology	biology	NOUN
fnp-3528	536	6	of	of	ADP
fnp-3528	536	7	the	the	DET
fnp-3528	536	8	blood	blood	NOUN
fnp-3528	536	9	-	-	PUNCT
fnp-3528	536	10	brain	brain	NOUN
fnp-3528	536	11	and	and	CCONJ
fnp-3528	536	12	the	the	DET
fnp-3528	536	13	blood	blood	NOUN
fnp-3528	536	14	-	-	PUNCT
fnp-3528	536	15	cerebrospinal	cerebrospinal	ADJ
fnp-3528	536	16	fluid	fluid	ADJ
fnp-3528	536	17	barriers	barrier	NOUN
fnp-3528	536	18	:	:	PUNCT
fnp-3528	536	19	similarities	similarity	NOUN
fnp-3528	536	20	and	and	CCONJ
fnp-3528	536	21	differences	difference	NOUN
fnp-3528	536	22	.	.	PUNCT
fnp-3528	537	1	fluids	fluid	NOUN
fnp-3528	537	2	barriers	barrier	NOUN
fnp-3528	537	3	cns	cns	PROPN
fnp-3528	537	4	2011	2011	NUM
fnp-3528	537	5	,	,	PUNCT
fnp-3528	537	6	8	8	NUM
fnp-3528	537	7	,	,	PUNCT
fnp-3528	537	8	3	3	NUM
fnp-3528	537	9	.	.	PUNCT
fnp-3528	537	10	kortekaas	kortekaas	NOUN
fnp-3528	537	11	,	,	PUNCT
fnp-3528	537	12	r.	r.	PROPN
fnp-3528	537	13	;	;	PUNCT
fnp-3528	537	14	leenders	leenders	PROPN
fnp-3528	537	15	,	,	PUNCT
fnp-3528	537	16	k.	k.	PROPN
fnp-3528	537	17	l.	l.	PROPN
fnp-3528	537	18	;	;	PUNCT
fnp-3528	537	19	van	van	PROPN
fnp-3528	537	20	oostrom	oostrom	PROPN
fnp-3528	537	21	,	,	PUNCT
fnp-3528	537	22	j.	j.	PROPN
fnp-3528	537	23	c.	c.	PROPN
fnp-3528	537	24	;	;	PUNCT
fnp-3528	537	25	vaalburg	vaalburg	PROPN
fnp-3528	537	26	,	,	PUNCT
fnp-3528	537	27	w.	w.	PROPN
fnp-3528	537	28	;	;	PUNCT
fnp-3528	537	29	bart	bart	PROPN
fnp-3528	537	30	,	,	PUNCT
fnp-3528	537	31	j.	j.	PROPN
fnp-3528	537	32	;	;	PUNCT
fnp-3528	537	33	willemsen	willemsen	NOUN
fnp-3528	537	34	,	,	PUNCT
fnp-3528	537	35	a.	a.	NOUN
fnp-3528	537	36	t.	t.	PROPN
fnp-3528	537	37	;	;	PUNCT
fnp-3528	537	38	hendrikse	hendrikse	NOUN
fnp-3528	537	39	,	,	PUNCT
fnp-3528	537	40	n.	n.	PROPN
fnp-3528	537	41	h.	h.	PROPN
fnp-3528	537	42	blood	blood	NOUN
fnp-3528	537	43	-	-	PUNCT
fnp-3528	537	44	brain	brain	NOUN
fnp-3528	537	45	barrier	barrier	NOUN
fnp-3528	537	46	dysfunction	dysfunction	NOUN
fnp-3528	537	47	in	in	ADP
fnp-3528	537	48	parkinsonian	parkinsonian	ADJ
fnp-3528	537	49	midbrain	midbrain	NOUN
fnp-3528	537	50	in	in	ADP
fnp-3528	537	51	vivo	vivo	NOUN
fnp-3528	537	52	.	.	PUNCT
fnp-3528	538	1	ann	ann	PROPN
fnp-3528	538	2	neurol	neurol	PROPN
fnp-3528	538	3	2005	2005	NUM
fnp-3528	538	4	,	,	PUNCT
fnp-3528	538	5	57	57	NUM
fnp-3528	538	6	,	,	PUNCT
fnp-3528	538	7	176	176	NUM
fnp-3528	538	8	-	-	SYM
fnp-3528	538	9	9	9	NUM
fnp-3528	538	10	.	.	PUNCT
fnp-3528	539	1	jha	jha	PROPN
fnp-3528	539	2	,	,	PUNCT
fnp-3528	539	3	n.	n.	PROPN
fnp-3528	539	4	k.	k.	PROPN
fnp-3528	539	5	;	;	PUNCT
fnp-3528	539	6	kar	kar	PROPN
fnp-3528	539	7	,	,	PUNCT
fnp-3528	539	8	r.	r.	PROPN
fnp-3528	539	9	;	;	PUNCT
fnp-3528	539	10	niranjan	niranjan	PROPN
fnp-3528	539	11	,	,	PUNCT
fnp-3528	539	12	r.	r.	PROPN
fnp-3528	539	13	abc	abc	PROPN
fnp-3528	539	14	transporters	transporter	NOUN
fnp-3528	539	15	in	in	ADP
fnp-3528	539	16	neurological	neurological	ADJ
fnp-3528	539	17	disorders	disorder	NOUN
fnp-3528	539	18	:	:	PUNCT
fnp-3528	539	19	an	an	DET
fnp-3528	539	20	important	important	ADJ
fnp-3528	539	21	gateway	gateway	NOUN
fnp-3528	539	22	for	for	ADP
fnp-3528	539	23	botanical	botanical	ADJ
fnp-3528	539	24	compounds	compound	NOUN
fnp-3528	539	25	mediated	mediate	VERB
fnp-3528	539	26	neuro	neuro	NOUN
fnp-3528	539	27	-	-	PUNCT
fnp-3528	539	28	therapeutics	therapeutic	NOUN
fnp-3528	539	29	.	.	PUNCT
fnp-3528	540	1	curr	curr	PROPN
fnp-3528	540	2	top	top	ADJ
fnp-3528	540	3	med	med	ADJ
fnp-3528	540	4	chem	chem	NOUN
fnp-3528	540	5	2019	2019	NUM
fnp-3528	540	6	,	,	PUNCT
fnp-3528	540	7	19	19	NUM
fnp-3528	540	8	,	,	PUNCT
fnp-3528	540	9	795	795	NUM
fnp-3528	540	10	-	-	SYM
fnp-3528	540	11	811	811	NUM
fnp-3528	540	12	.	.	PUNCT
fnp-3528	540	13	jablonski	jablonski	PROPN
fnp-3528	540	14	,	,	PUNCT
fnp-3528	540	15	m.	m.	NOUN
fnp-3528	540	16	r.	r.	PROPN
fnp-3528	540	17	;	;	PUNCT
fnp-3528	540	18	markandaiah	markandaiah	PROPN
fnp-3528	540	19	,	,	PUNCT
fnp-3528	540	20	s.	s.	PROPN
fnp-3528	540	21	s.	s.	PROPN
fnp-3528	540	22	;	;	PUNCT
fnp-3528	540	23	jacob	jacob	PROPN
fnp-3528	540	24	,	,	PUNCT
fnp-3528	540	25	d.	d.	PROPN
fnp-3528	540	26	;	;	PUNCT
fnp-3528	540	27	meng	meng	PROPN
fnp-3528	540	28	,	,	PUNCT
fnp-3528	540	29	n.	n.	PROPN
fnp-3528	540	30	j.	j.	PROPN
fnp-3528	540	31	;	;	PUNCT
fnp-3528	540	32	li	li	PROPN
fnp-3528	540	33	,	,	PUNCT
fnp-3528	540	34	k.	k.	PROPN
fnp-3528	540	35	;	;	PUNCT
fnp-3528	540	36	gennaro	gennaro	PROPN
fnp-3528	540	37	,	,	PUNCT
fnp-3528	540	38	v.	v.	PROPN
fnp-3528	540	39	;	;	PUNCT
fnp-3528	540	40	lepore	lepore	PROPN
fnp-3528	540	41	,	,	PUNCT
fnp-3528	540	42	a.	a.	PROPN
fnp-3528	540	43	c.	c.	PROPN
fnp-3528	540	44	;	;	PUNCT
fnp-3528	540	45	trotti	trotti	PROPN
fnp-3528	540	46	,	,	PUNCT
fnp-3528	540	47	d.	d.	PROPN
fnp-3528	540	48	;	;	PUNCT
fnp-3528	540	49	pasinelli	pasinelli	PROPN
fnp-3528	540	50	,	,	PUNCT
fnp-3528	540	51	p.	p.	NOUN
fnp-3528	540	52	inhibiting	inhibit	VERB
fnp-3528	540	53	drug	drug	NOUN
fnp-3528	540	54	efflux	efflux	NOUN
fnp-3528	540	55	transporters	transporter	NOUN
fnp-3528	540	56	improves	improve	VERB
fnp-3528	540	57	efficacy	efficacy	NOUN
fnp-3528	540	58	of	of	ADP
fnp-3528	540	59	als	als	NOUN
fnp-3528	540	60	therapeutics	therapeutic	NOUN
fnp-3528	540	61	.	.	PUNCT
fnp-3528	541	1	ann	ann	PROPN
fnp-3528	541	2	clin	clin	PROPN
fnp-3528	541	3	transl	transl	PROPN
fnp-3528	541	4	neurol	neurol	PROPN
fnp-3528	541	5	2014	2014	NUM
fnp-3528	541	6	,	,	PUNCT
fnp-3528	541	7	1	1	NUM
fnp-3528	541	8	,	,	PUNCT
fnp-3528	541	9	996	996	NUM
fnp-3528	541	10	-	-	SYM
fnp-3528	541	11	1005	1005	NUM
fnp-3528	541	12	.	.	PUNCT
fnp-3528	542	1	kooij	kooij	PROPN
fnp-3528	542	2	,	,	PUNCT
fnp-3528	542	3	g.	g.	PROPN
fnp-3528	542	4	;	;	PUNCT
fnp-3528	542	5	kroon	kroon	PROPN
fnp-3528	542	6	,	,	PUNCT
fnp-3528	542	7	j.	j.	PROPN
fnp-3528	542	8	;	;	PUNCT
fnp-3528	542	9	paul	paul	PROPN
fnp-3528	542	10	,	,	PUNCT
fnp-3528	542	11	d.	d.	PROPN
fnp-3528	542	12	;	;	PUNCT
fnp-3528	542	13	reijerkerk	reijerkerk	PROPN
fnp-3528	542	14	,	,	PUNCT
fnp-3528	542	15	a.	a.	NOUN
fnp-3528	542	16	;	;	PUNCT
fnp-3528	542	17	geerts	geert	NOUN
fnp-3528	542	18	,	,	PUNCT
fnp-3528	542	19	d.	d.	PROPN
fnp-3528	542	20	;	;	PUNCT
fnp-3528	542	21	van	van	PROPN
fnp-3528	542	22	der	der	PROPN
fnp-3528	542	23	pol	pol	PROPN
fnp-3528	542	24	,	,	PUNCT
fnp-3528	542	25	s.	s.	PROPN
fnp-3528	542	26	m.	m.	PROPN
fnp-3528	542	27	;	;	PUNCT
fnp-3528	542	28	van	van	PROPN
fnp-3528	542	29	het	het	PROPN
fnp-3528	542	30	hof	hof	PROPN
fnp-3528	542	31	,	,	PUNCT
fnp-3528	542	32	b.	b.	PROPN
fnp-3528	542	33	;	;	PUNCT
fnp-3528	542	34	drexhage	drexhage	PROPN
fnp-3528	542	35	,	,	PUNCT
fnp-3528	542	36	j.	j.	PROPN
fnp-3528	542	37	a.	a.	PROPN
fnp-3528	542	38	;	;	PUNCT
fnp-3528	542	39	van	van	PROPN
fnp-3528	542	40	vliet	vliet	PROPN
fnp-3528	542	41	,	,	PUNCT
fnp-3528	542	42	s.	s.	PROPN
fnp-3528	542	43	j.	j.	PROPN
fnp-3528	542	44	;	;	PUNCT
fnp-3528	542	45	hekking	hekking	PROPN
fnp-3528	542	46	,	,	PUNCT
fnp-3528	542	47	l.	l.	PROPN
fnp-3528	542	48	h.	h.	PROPN
fnp-3528	542	49	;	;	PUNCT
fnp-3528	542	50	van	van	PROPN
fnp-3528	542	51	buul	buul	NOUN
fnp-3528	542	52	,	,	PUNCT
fnp-3528	542	53	j.	j.	PROPN
fnp-3528	542	54	d.	d.	PROPN
fnp-3528	542	55	;	;	PUNCT
fnp-3528	542	56	pachter	pachter	PROPN
fnp-3528	542	57	,	,	PUNCT
fnp-3528	542	58	j.	j.	PROPN
fnp-3528	542	59	s.	s.	PROPN
fnp-3528	542	60	;	;	PUNCT
fnp-3528	542	61	de	de	PROPN
fnp-3528	542	62	vries	vries	PROPN
fnp-3528	542	63	,	,	PUNCT
fnp-3528	542	64	h.	h.	PROPN
fnp-3528	542	65	e.	e.	PROPN
fnp-3528	542	66	p	p	PROPN
fnp-3528	542	67	-	-	PUNCT
fnp-3528	542	68	glycoprotein	glycoprotein	NOUN
fnp-3528	542	69	regulates	regulate	VERB
fnp-3528	542	70	trafficking	trafficking	NOUN
fnp-3528	542	71	of	of	ADP
fnp-3528	542	72	cd8(+	cd8(+	PROPN
fnp-3528	542	73	)	)	PUNCT
fnp-3528	542	74	t	t	PROPN
fnp-3528	542	75	cells	cell	NOUN
fnp-3528	542	76	to	to	ADP
fnp-3528	542	77	the	the	DET
fnp-3528	542	78	brain	brain	NOUN
fnp-3528	542	79	parenchyma	parenchyma	NOUN
fnp-3528	542	80	.	.	PUNCT
fnp-3528	543	1	acta	acta	PROPN
fnp-3528	543	2	neuropathol	neuropathol	PROPN
fnp-3528	543	3	2014	2014	NUM
fnp-3528	543	4	,	,	PUNCT
fnp-3528	543	5	127	127	NUM
fnp-3528	543	6	,	,	PUNCT
fnp-3528	543	7	699	699	NUM
fnp-3528	543	8	-	-	SYM
fnp-3528	543	9	711	711	NUM
fnp-3528	543	10	.	.	PUNCT
fnp-3528	544	1	jablonski	jablonski	PROPN
fnp-3528	544	2	,	,	PUNCT
fnp-3528	544	3	m.	m.	PROPN
fnp-3528	544	4	r.	r.	PROPN
fnp-3528	544	5	;	;	PUNCT
fnp-3528	544	6	jacob	jacob	PROPN
fnp-3528	544	7	,	,	PUNCT
fnp-3528	544	8	d.	d.	PROPN
fnp-3528	544	9	a.	a.	PROPN
fnp-3528	544	10	;	;	PUNCT
fnp-3528	544	11	campos	campos	PROPN
fnp-3528	544	12	,	,	PUNCT
fnp-3528	544	13	c.	c.	PROPN
fnp-3528	544	14	;	;	PUNCT
fnp-3528	544	15	miller	miller	PROPN
fnp-3528	544	16	,	,	PUNCT
fnp-3528	544	17	d.	d.	PROPN
fnp-3528	544	18	s.	s.	PROPN
fnp-3528	544	19	;	;	PUNCT
fnp-3528	544	20	maragakis	maragakis	PROPN
fnp-3528	544	21	,	,	PUNCT
fnp-3528	544	22	n.	n.	PROPN
fnp-3528	544	23	j.	j.	PROPN
fnp-3528	544	24	;	;	PUNCT
fnp-3528	544	25	pasinelli	pasinelli	PROPN
fnp-3528	544	26	,	,	PUNCT
fnp-3528	544	27	p.	p.	NOUN
fnp-3528	544	28	;	;	PUNCT
fnp-3528	544	29	trotti	trotti	PROPN
fnp-3528	544	30	,	,	PUNCT
fnp-3528	544	31	d.	d.	NOUN
fnp-3528	544	32	selective	selective	ADJ
fnp-3528	544	33	increase	increase	NOUN
fnp-3528	544	34	of	of	ADP
fnp-3528	544	35	two	two	NUM
fnp-3528	544	36	abc	abc	PROPN
fnp-3528	544	37	drug	drug	NOUN
fnp-3528	544	38	efflux	efflux	NOUN
fnp-3528	544	39	transporters	transporter	NOUN
fnp-3528	544	40	at	at	ADP
fnp-3528	544	41	the	the	DET
fnp-3528	544	42	blood	blood	NOUN
fnp-3528	544	43	-	-	PUNCT
fnp-3528	544	44	spinal	spinal	NOUN
fnp-3528	544	45	cord	cord	NOUN
fnp-3528	544	46	barrier	barrier	NOUN
fnp-3528	544	47	suggests	suggest	VERB
fnp-3528	544	48	induced	induce	VERB
fnp-3528	544	49	pharmacoresistance	pharmacoresistance	NOUN
fnp-3528	544	50	in	in	ADP
fnp-3528	544	51	als	als	NOUN
fnp-3528	544	52	.	.	PUNCT
fnp-3528	545	1	neurobiol	neurobiol	PROPN
fnp-3528	545	2	dis	dis	PROPN
fnp-3528	545	3	2012	2012	NUM
fnp-3528	545	4	,	,	PUNCT
fnp-3528	545	5	47	47	NUM
fnp-3528	545	6	,	,	PUNCT
fnp-3528	545	7	194	194	NUM
fnp-3528	545	8	-	-	SYM
fnp-3528	545	9	200	200	NUM
fnp-3528	545	10	.	.	PUNCT
fnp-3528	546	1	westerlund	westerlund	PROPN
fnp-3528	546	2	,	,	PUNCT
fnp-3528	546	3	m.	m.	NOUN
fnp-3528	546	4	;	;	PUNCT
fnp-3528	546	5	belin	belin	PROPN
fnp-3528	546	6	,	,	PUNCT
fnp-3528	546	7	a.	a.	PROPN
fnp-3528	546	8	c.	c.	PROPN
fnp-3528	546	9	;	;	PUNCT
fnp-3528	546	10	olson	olson	PROPN
fnp-3528	546	11	,	,	PUNCT
fnp-3528	546	12	l.	l.	PROPN
fnp-3528	546	13	;	;	PUNCT
fnp-3528	546	14	galter	galter	NOUN
fnp-3528	546	15	,	,	PUNCT
fnp-3528	546	16	d.	d.	NOUN
fnp-3528	546	17	expression	expression	NOUN
fnp-3528	546	18	of	of	ADP
fnp-3528	546	19	multi	multi	ADJ
fnp-3528	546	20	-	-	ADJ
fnp-3528	546	21	drug	drug	ADJ
fnp-3528	546	22	resistance	resistance	NOUN
fnp-3528	546	23	1	1	NUM
fnp-3528	546	24	mrna	mrna	NOUN
fnp-3528	546	25	in	in	ADP
fnp-3528	546	26	human	human	ADJ
fnp-3528	546	27	and	and	CCONJ
fnp-3528	546	28	rodent	rodent	ADJ
fnp-3528	546	29	tissues	tissue	NOUN
fnp-3528	546	30	:	:	PUNCT
fnp-3528	546	31	reduced	reduce	VERB
fnp-3528	546	32	levels	level	NOUN
fnp-3528	546	33	in	in	ADP
fnp-3528	546	34	parkinson	parkinson	NOUN
fnp-3528	546	35	patients	patient	NOUN
fnp-3528	546	36	.	.	PUNCT
fnp-3528	547	1	cell	cell	NOUN
fnp-3528	547	2	tissue	tissue	NOUN
fnp-3528	547	3	res	re	NOUN
fnp-3528	547	4	2008	2008	NUM
fnp-3528	547	5	,	,	PUNCT
fnp-3528	547	6	334	334	NUM
fnp-3528	547	7	,	,	PUNCT
fnp-3528	547	8	179	179	NUM
fnp-3528	547	9	-	-	SYM
fnp-3528	547	10	85	85	NUM
fnp-3528	547	11	.	.	PUNCT
fnp-3528	548	1	valenza	valenza	ADJ
fnp-3528	548	2	,	,	PUNCT
fnp-3528	548	3	m.	m.	NOUN
fnp-3528	548	4	;	;	PUNCT
fnp-3528	548	5	carroll	carroll	PROPN
fnp-3528	548	6	,	,	PUNCT
fnp-3528	548	7	j.	j.	PROPN
fnp-3528	548	8	b.	b.	PROPN
fnp-3528	548	9	;	;	PUNCT
fnp-3528	548	10	leoni	leoni	PROPN
fnp-3528	548	11	,	,	PUNCT
fnp-3528	548	12	v.	v.	PROPN
fnp-3528	548	13	;	;	PUNCT
fnp-3528	548	14	bertram	bertram	PROPN
fnp-3528	548	15	,	,	PUNCT
fnp-3528	548	16	l.	l.	PROPN
fnp-3528	548	17	n.	n.	PROPN
fnp-3528	548	18	;	;	PUNCT
fnp-3528	548	19	bjorkhem	bjorkhem	PROPN
fnp-3528	548	20	,	,	PUNCT
fnp-3528	548	21	i.	i.	PROPN
fnp-3528	548	22	;	;	PUNCT
fnp-3528	548	23	singaraja	singaraja	PROPN
fnp-3528	548	24	,	,	PUNCT
fnp-3528	548	25	r.	r.	PROPN
fnp-3528	548	26	r.	r.	PROPN
fnp-3528	548	27	;	;	PUNCT
fnp-3528	548	28	di	di	PROPN
fnp-3528	548	29	donato	donato	PROPN
fnp-3528	548	30	,	,	PUNCT
fnp-3528	548	31	s.	s.	PROPN
fnp-3528	548	32	;	;	PUNCT
fnp-3528	548	33	lutjohann	lutjohann	PROPN
fnp-3528	548	34	,	,	PUNCT
fnp-3528	548	35	d.	d.	PROPN
fnp-3528	548	36	;	;	PUNCT
fnp-3528	548	37	hayden	hayden	PROPN
fnp-3528	548	38	,	,	PUNCT
fnp-3528	548	39	m.	m.	PROPN
fnp-3528	548	40	r.	r.	PROPN
fnp-3528	548	41	;	;	PUNCT
fnp-3528	548	42	cattaneo	cattaneo	PROPN
fnp-3528	548	43	,	,	PUNCT
fnp-3528	548	44	e.	e.	PROPN
fnp-3528	548	45	cholesterol	cholesterol	PROPN
fnp-3528	548	46	biosynthesis	biosynthesis	NOUN
fnp-3528	548	47	pathway	pathway	NOUN
fnp-3528	548	48	is	be	AUX
fnp-3528	548	49	disturbed	disturb	VERB
fnp-3528	548	50	in	in	ADP
fnp-3528	548	51	yac128	yac128	NOUN
fnp-3528	548	52	mice	mouse	NOUN
fnp-3528	548	53	and	and	CCONJ
fnp-3528	548	54	is	be	AUX
fnp-3528	548	55	modulated	modulate	VERB
fnp-3528	548	56	by	by	ADP
fnp-3528	548	57	huntingtin	huntingtin	PROPN
fnp-3528	548	58	mutation	mutation	NOUN
fnp-3528	548	59	.	.	PUNCT
fnp-3528	549	1	hum	hum	PROPN
fnp-3528	549	2	mol	mol	ADP
fnp-3528	549	3	genet	genet	PROPN
fnp-3528	549	4	2007	2007	NUM
fnp-3528	549	5	,	,	PUNCT
fnp-3528	549	6	16	16	NUM
fnp-3528	549	7	,	,	PUNCT
fnp-3528	549	8	2187	2187	NUM
fnp-3528	549	9	-	-	SYM
fnp-3528	549	10	98	98	NUM
fnp-3528	549	11	.	.	PUNCT
fnp-3528	550	1	dombrowski	dombrowski	PROPN
fnp-3528	550	2	,	,	PUNCT
fnp-3528	550	3	s.	s.	PROPN
fnp-3528	550	4	m.	m.	PROPN
fnp-3528	550	5	;	;	PUNCT
fnp-3528	550	6	desai	desai	PROPN
fnp-3528	550	7	,	,	PUNCT
fnp-3528	550	8	s.	s.	PROPN
fnp-3528	550	9	y.	y.	PROPN
fnp-3528	550	10	;	;	PUNCT
fnp-3528	550	11	marroni	marroni	PROPN
fnp-3528	550	12	,	,	PUNCT
fnp-3528	550	13	m.	m.	NOUN
fnp-3528	550	14	;	;	PUNCT
fnp-3528	551	1	cucullo	cucullo	PROPN
fnp-3528	551	2	,	,	PUNCT
fnp-3528	551	3	l.	l.	PROPN
fnp-3528	551	4	;	;	PUNCT
fnp-3528	551	5	goodrich	goodrich	PROPN
fnp-3528	551	6	,	,	PUNCT
fnp-3528	551	7	k.	k.	PROPN
fnp-3528	551	8	;	;	PUNCT
fnp-3528	551	9	bingaman	bingaman	NOUN
fnp-3528	551	10	,	,	PUNCT
fnp-3528	551	11	w.	w.	PROPN
fnp-3528	551	12	;	;	PUNCT
fnp-3528	551	13	mayberg	mayberg	PROPN
fnp-3528	551	14	,	,	PUNCT
fnp-3528	551	15	m.	m.	PROPN
fnp-3528	551	16	r.	r.	PROPN
fnp-3528	551	17	;	;	PUNCT
fnp-3528	551	18	bengez	bengez	PROPN
fnp-3528	551	19	,	,	PUNCT
fnp-3528	551	20	l.	l.	PROPN
fnp-3528	551	21	;	;	PUNCT
fnp-3528	551	22	janigro	janigro	PROPN
fnp-3528	551	23	,	,	PUNCT
fnp-3528	551	24	d.	d.	PROPN
fnp-3528	551	25	overexpression	overexpression	NOUN
fnp-3528	551	26	of	of	ADP
fnp-3528	551	27	multiple	multiple	ADJ
fnp-3528	551	28	drug	drug	NOUN
fnp-3528	551	29	resistance	resistance	NOUN
fnp-3528	551	30	genes	gene	NOUN
fnp-3528	551	31	in	in	ADP
fnp-3528	551	32	endothelial	endothelial	ADJ
fnp-3528	551	33	cells	cell	NOUN
fnp-3528	551	34	from	from	ADP
fnp-3528	551	35	patients	patient	NOUN
fnp-3528	551	36	with	with	ADP
fnp-3528	551	37	refractory	refractory	NOUN
fnp-3528	551	38	epilepsy	epilepsy	NOUN
fnp-3528	551	39	.	.	PUNCT
fnp-3528	552	1	epilepsia	epilepsia	NOUN
fnp-3528	552	2	2001	2001	NUM
fnp-3528	552	3	,	,	PUNCT
fnp-3528	552	4	42	42	NUM
fnp-3528	552	5	,	,	PUNCT
fnp-3528	552	6	1501	1501	NUM
fnp-3528	552	7	-	-	SYM
fnp-3528	552	8	6	6	NUM
fnp-3528	552	9	.	.	PUNCT
fnp-3528	552	10	sisodiya	sisodiya	PROPN
fnp-3528	552	11	,	,	PUNCT
fnp-3528	552	12	s.	s.	PROPN
fnp-3528	552	13	m.	m.	PROPN
fnp-3528	552	14	;	;	PUNCT
fnp-3528	552	15	lin	lin	PROPN
fnp-3528	552	16	,	,	PUNCT
fnp-3528	552	17	w.	w.	PROPN
fnp-3528	552	18	r.	r.	PROPN
fnp-3528	552	19	;	;	PUNCT
fnp-3528	552	20	harding	harding	PROPN
fnp-3528	552	21	,	,	PUNCT
fnp-3528	552	22	b.	b.	PROPN
fnp-3528	552	23	n.	n.	PROPN
fnp-3528	552	24	;	;	PUNCT
fnp-3528	552	25	squier	squier	NOUN
fnp-3528	552	26	,	,	PUNCT
fnp-3528	552	27	m.	m.	NOUN
fnp-3528	552	28	v.	v.	PROPN
fnp-3528	552	29	;	;	PUNCT
fnp-3528	552	30	thom	thom	NOUN
fnp-3528	552	31	,	,	PUNCT
fnp-3528	552	32	m.	m.	NOUN
fnp-3528	552	33	drug	drug	NOUN
fnp-3528	552	34	resistance	resistance	NOUN
fnp-3528	552	35	in	in	ADP
fnp-3528	552	36	epilepsy	epilepsy	NOUN
fnp-3528	552	37	:	:	PUNCT
fnp-3528	552	38	expression	expression	NOUN
fnp-3528	552	39	of	of	ADP
fnp-3528	552	40	drug	drug	NOUN
fnp-3528	552	41	resistance	resistance	NOUN
fnp-3528	552	42	proteins	protein	NOUN
fnp-3528	552	43	in	in	ADP
fnp-3528	552	44	common	common	ADJ
fnp-3528	552	45	causes	cause	NOUN
fnp-3528	552	46	of	of	ADP
fnp-3528	552	47	refractory	refractory	NOUN
fnp-3528	552	48	epilepsy	epilepsy	NOUN
fnp-3528	552	49	.	.	PUNCT
fnp-3528	553	1	brain	brain	PROPN
fnp-3528	553	2	2002	2002	NUM
fnp-3528	553	3	,	,	PUNCT
fnp-3528	553	4	125	125	NUM
fnp-3528	553	5	,	,	PUNCT
fnp-3528	553	6	22	22	NUM
fnp-3528	553	7	-	-	SYM
fnp-3528	553	8	31	31	NUM
fnp-3528	553	9	.	.	PUNCT
fnp-3528	554	1	katzeff	katzeff	PROPN
fnp-3528	554	2	,	,	PUNCT
fnp-3528	554	3	j.	j.	PROPN
fnp-3528	554	4	s.	s.	PROPN
fnp-3528	554	5	;	;	PUNCT
fnp-3528	554	6	kim	kim	PROPN
fnp-3528	554	7	,	,	PUNCT
fnp-3528	554	8	w.	w.	PROPN
fnp-3528	554	9	s.	s.	PROPN
fnp-3528	554	10	atp	atp	PROPN
fnp-3528	554	11	-	-	PUNCT
fnp-3528	554	12	binding	bind	VERB
fnp-3528	554	13	cassette	cassette	NOUN
fnp-3528	554	14	transporters	transporter	NOUN
fnp-3528	554	15	and	and	CCONJ
fnp-3528	554	16	neurodegenerative	neurodegenerative	ADJ
fnp-3528	554	17	diseases	disease	NOUN
fnp-3528	554	18	.	.	PUNCT
fnp-3528	555	1	essays	essays	PROPN
fnp-3528	555	2	biochem	biochem	NOUN
fnp-3528	555	3	2021	2021	NUM
fnp-3528	555	4	ebc20210012	ebc20210012	NOUN
fnp-3528	555	5	.	.	PUNCT
fnp-3528	556	1	dinda	dinda	PROPN
fnp-3528	556	2	,	,	PUNCT
fnp-3528	556	3	b.	b.	PROPN
fnp-3528	556	4	;	;	PUNCT
fnp-3528	556	5	dinda	dinda	PROPN
fnp-3528	556	6	,	,	PUNCT
fnp-3528	556	7	m.	m.	NOUN
fnp-3528	556	8	;	;	PUNCT
fnp-3528	556	9	kulsi	kulsi	NOUN
fnp-3528	556	10	,	,	PUNCT
fnp-3528	556	11	g.	g.	PROPN
fnp-3528	556	12	;	;	PUNCT
fnp-3528	556	13	chakraborty	chakraborty	PROPN
fnp-3528	556	14	,	,	PUNCT
fnp-3528	556	15	a.	a.	PROPN
fnp-3528	556	16	;	;	PUNCT
fnp-3528	556	17	dinda	dinda	PROPN
fnp-3528	556	18	,	,	PUNCT
fnp-3528	556	19	s.	s.	PROPN
fnp-3528	556	20	therapeutic	therapeutic	ADJ
fnp-3528	556	21	potentials	potential	NOUN
fnp-3528	556	22	of	of	ADP
fnp-3528	556	23	plant	plant	NOUN
fnp-3528	556	24	iridoids	iridoid	NOUN
fnp-3528	556	25	in	in	ADP
fnp-3528	556	26	alzheimer	alzheimer	PROPN
fnp-3528	556	27	's	's	PART
fnp-3528	556	28	and	and	CCONJ
fnp-3528	556	29	parkinson	parkinson	NOUN
fnp-3528	556	30	's	's	PART
fnp-3528	556	31	diseases	disease	NOUN
fnp-3528	556	32	:	:	PUNCT
fnp-3528	556	33	a	a	DET
fnp-3528	556	34	review	review	NOUN
fnp-3528	556	35	.	.	PUNCT
fnp-3528	557	1	eur	eur	PROPN
fnp-3528	557	2	j	j	PROPN
fnp-3528	557	3	med	med	PROPN
fnp-3528	557	4	chem	chem	NOUN
fnp-3528	557	5	2019	2019	NUM
fnp-3528	557	6	,	,	PUNCT
fnp-3528	557	7	169	169	NUM
fnp-3528	557	8	,	,	PUNCT
fnp-3528	557	9	185	185	NUM
fnp-3528	557	10	-	-	SYM
fnp-3528	557	11	99	99	NUM
fnp-3528	557	12	.	.	PUNCT
fnp-3528	557	13	pahnke	pahnke	PROPN
fnp-3528	557	14	,	,	PUNCT
fnp-3528	557	15	j.	j.	PROPN
fnp-3528	557	16	;	;	PUNCT
fnp-3528	557	17	langer	langer	NOUN
fnp-3528	557	18	,	,	PUNCT
fnp-3528	557	19	o.	o.	PROPN
fnp-3528	557	20	;	;	PUNCT
fnp-3528	557	21	krohn	krohn	PROPN
fnp-3528	557	22	,	,	PUNCT
fnp-3528	557	23	m.	m.	PROPN
fnp-3528	557	24	alzheimer	alzheimer	PROPN
fnp-3528	557	25	's	's	PART
fnp-3528	557	26	and	and	CCONJ
fnp-3528	557	27	abc	abc	PROPN
fnp-3528	557	28	transporters	transporter	NOUN
fnp-3528	557	29	--	--	PUNCT
fnp-3528	557	30	new	new	ADJ
fnp-3528	557	31	opportunities	opportunity	NOUN
fnp-3528	557	32	for	for	ADP
fnp-3528	557	33	diagnostics	diagnostic	NOUN
fnp-3528	557	34	and	and	CCONJ
fnp-3528	557	35	treatment	treatment	NOUN
fnp-3528	557	36	.	.	PUNCT
fnp-3528	558	1	neurobiol	neurobiol	PROPN
fnp-3528	558	2	dis	dis	PROPN
fnp-3528	558	3	2014	2014	NUM
fnp-3528	558	4	,	,	PUNCT
fnp-3528	558	5	72	72	NUM
fnp-3528	558	6	pt	pt	NOUN
fnp-3528	558	7	a	a	PRON
fnp-3528	558	8	,	,	PUNCT
fnp-3528	558	9	54	54	NUM
fnp-3528	558	10	-	-	SYM
fnp-3528	558	11	60	60	NUM
fnp-3528	558	12	.	.	PUNCT
fnp-3528	559	1	susa	susa	NOUN
fnp-3528	559	2	,	,	PUNCT
fnp-3528	559	3	m.	m.	NOUN
fnp-3528	559	4	;	;	PUNCT
fnp-3528	559	5	iyer	iyer	PROPN
fnp-3528	559	6	,	,	PUNCT
fnp-3528	559	7	a.	a.	PROPN
fnp-3528	559	8	k.	k.	PROPN
fnp-3528	559	9	;	;	PUNCT
fnp-3528	559	10	ryu	ryu	PROPN
fnp-3528	559	11	,	,	PUNCT
fnp-3528	559	12	k.	k.	PROPN
fnp-3528	559	13	;	;	PUNCT
fnp-3528	559	14	choy	choy	PROPN
fnp-3528	559	15	,	,	PUNCT
fnp-3528	559	16	e.	e.	PROPN
fnp-3528	559	17	;	;	PUNCT
fnp-3528	559	18	hornicek	hornicek	PROPN
fnp-3528	559	19	,	,	PUNCT
fnp-3528	559	20	f.	f.	PROPN
fnp-3528	559	21	j.	j.	PROPN
fnp-3528	559	22	;	;	PUNCT
fnp-3528	559	23	mankin	mankin	PROPN
fnp-3528	559	24	,	,	PUNCT
fnp-3528	559	25	h.	h.	PROPN
fnp-3528	559	26	;	;	PUNCT
fnp-3528	559	27	milane	milane	NOUN
fnp-3528	559	28	,	,	PUNCT
fnp-3528	559	29	l.	l.	PROPN
fnp-3528	559	30	;	;	PUNCT
fnp-3528	559	31	amiji	amiji	NOUN
fnp-3528	559	32	,	,	PUNCT
fnp-3528	559	33	m.	m.	NOUN
fnp-3528	559	34	m.	m.	NOUN
fnp-3528	559	35	;	;	PUNCT
fnp-3528	559	36	duan	duan	PROPN
fnp-3528	559	37	,	,	PUNCT
fnp-3528	559	38	z.	z.	PROPN
fnp-3528	559	39	inhibition	inhibition	NOUN
fnp-3528	559	40	of	of	ADP
fnp-3528	559	41	abcb1	abcb1	NOUN
fnp-3528	559	42	(	(	PUNCT
fnp-3528	559	43	mdr1	mdr1	PROPN
fnp-3528	559	44	)	)	PUNCT
fnp-3528	559	45	expression	expression	NOUN
fnp-3528	559	46	by	by	ADP
fnp-3528	559	47	an	an	DET
fnp-3528	559	48	sirna	sirna	PROPN
fnp-3528	559	49	nanoparticulate	nanoparticulate	PROPN
fnp-3528	559	50	delivery	delivery	NOUN
fnp-3528	559	51	system	system	NOUN
fnp-3528	559	52	to	to	PART
fnp-3528	559	53	overcome	overcome	VERB
fnp-3528	559	54	drug	drug	NOUN
fnp-3528	559	55	resistance	resistance	NOUN
fnp-3528	559	56	in	in	ADP
fnp-3528	559	57	osteosarcoma	osteosarcoma	NOUN
fnp-3528	559	58	.	.	PUNCT
fnp-3528	560	1	plos	plos	PROPN
fnp-3528	560	2	one	one	NUM
fnp-3528	560	3	2010	2010	NUM
fnp-3528	560	4	,	,	PUNCT
fnp-3528	560	5	5	5	NUM
fnp-3528	560	6	,	,	PUNCT
fnp-3528	560	7	e10764	e10764	NOUN
fnp-3528	560	8	.	.	PUNCT
fnp-3528	561	1	robillard	robillard	PROPN
fnp-3528	561	2	,	,	PUNCT
fnp-3528	561	3	k.	k.	PROPN
fnp-3528	561	4	r.	r.	PROPN
fnp-3528	561	5	;	;	PUNCT
fnp-3528	561	6	hoque	hoque	NOUN
fnp-3528	561	7	,	,	PUNCT
fnp-3528	561	8	m.	m.	NOUN
fnp-3528	561	9	t.	t.	PROPN
fnp-3528	561	10	;	;	PUNCT
fnp-3528	561	11	bendayan	bendayan	PROPN
fnp-3528	561	12	,	,	PUNCT
fnp-3528	561	13	r.	r.	NOUN
fnp-3528	561	14	expression	expression	NOUN
fnp-3528	561	15	of	of	ADP
fnp-3528	561	16	atp	atp	PROPN
fnp-3528	561	17	-	-	PUNCT
fnp-3528	561	18	binding	bind	VERB
fnp-3528	561	19	cassette	cassette	NOUN
fnp-3528	561	20	membrane	membrane	NOUN
fnp-3528	561	21	transporters	transporter	NOUN
fnp-3528	561	22	in	in	ADP
fnp-3528	561	23	a	a	DET
fnp-3528	561	24	hiv-1	hiv-1	X
fnp-3528	561	25	transgenic	transgenic	ADJ
fnp-3528	561	26	rat	rat	NOUN
fnp-3528	561	27	model	model	NOUN
fnp-3528	561	28	.	.	PUNCT
fnp-3528	562	1	biochem	biochem	PROPN
fnp-3528	562	2	biophys	biophys	PROPN
fnp-3528	562	3	res	res	PROPN
fnp-3528	562	4	commun	commun	PROPN
fnp-3528	562	5	2014	2014	NUM
fnp-3528	562	6	,	,	PUNCT
fnp-3528	562	7	444	444	NUM
fnp-3528	562	8	,	,	PUNCT
fnp-3528	562	9	531	531	NUM
fnp-3528	562	10	-	-	SYM
fnp-3528	562	11	6	6	NUM
fnp-3528	562	12	.	.	PUNCT
fnp-3528	563	1	hayashi	hayashi	PROPN
fnp-3528	563	2	,	,	PUNCT
fnp-3528	563	3	k.	k.	PROPN
fnp-3528	563	4	;	;	PUNCT
fnp-3528	563	5	pu	pu	PROPN
fnp-3528	563	6	,	,	PUNCT
fnp-3528	563	7	h.	h.	PROPN
fnp-3528	563	8	;	;	PUNCT
fnp-3528	563	9	tian	tian	PROPN
fnp-3528	563	10	,	,	PUNCT
fnp-3528	563	11	j.	j.	PROPN
fnp-3528	563	12	;	;	PUNCT
fnp-3528	563	13	andras	andras	PROPN
fnp-3528	563	14	,	,	PUNCT
fnp-3528	563	15	i.	i.	PROPN
fnp-3528	563	16	e.	e.	PROPN
fnp-3528	563	17	;	;	PUNCT
fnp-3528	563	18	lee	lee	PROPN
fnp-3528	563	19	,	,	PUNCT
fnp-3528	563	20	y.	y.	PROPN
fnp-3528	563	21	w.	w.	PROPN
fnp-3528	563	22	;	;	PUNCT
fnp-3528	563	23	hennig	hennig	PROPN
fnp-3528	563	24	,	,	PUNCT
fnp-3528	563	25	b.	b.	PROPN
fnp-3528	563	26	;	;	PUNCT
fnp-3528	563	27	toborek	toborek	NOUN
fnp-3528	563	28	,	,	PUNCT
fnp-3528	563	29	m.	m.	NOUN
fnp-3528	563	30	hiv	hiv	PROPN
fnp-3528	563	31	-	-	PUNCT
fnp-3528	563	32	tat	tat	NOUN
fnp-3528	563	33	protein	protein	NOUN
fnp-3528	563	34	induces	induce	VERB
fnp-3528	563	35	p	p	ADJ
fnp-3528	563	36	-	-	PUNCT
fnp-3528	563	37	glycoprotein	glycoprotein	NOUN
fnp-3528	563	38	expression	expression	NOUN
fnp-3528	563	39	in	in	ADP
fnp-3528	563	40	brain	brain	NOUN
fnp-3528	563	41	microvascular	microvascular	NOUN
fnp-3528	563	42	endothelial	endothelial	ADJ
fnp-3528	563	43	cells	cell	NOUN
fnp-3528	563	44	.	.	PUNCT
fnp-3528	564	1	j	j	PROPN
fnp-3528	564	2	neurochem	neurochem	PROPN
fnp-3528	564	3	2005	2005	NUM
fnp-3528	564	4	,	,	PUNCT
fnp-3528	564	5	93	93	NUM
fnp-3528	564	6	,	,	PUNCT
fnp-3528	564	7	1231	1231	NUM
fnp-3528	564	8	-	-	SYM
fnp-3528	564	9	41	41	NUM
fnp-3528	564	10	.	.	PUNCT
fnp-3528	565	1	matsuo	matsuo	PROPN
fnp-3528	565	2	,	,	PUNCT
fnp-3528	565	3	h.	h.	PROPN
fnp-3528	565	4	;	;	PUNCT
fnp-3528	565	5	tomiyama	tomiyama	PROPN
fnp-3528	565	6	,	,	PUNCT
fnp-3528	565	7	h.	h.	PROPN
fnp-3528	565	8	;	;	PUNCT
fnp-3528	565	9	satake	satake	VERB
fnp-3528	565	10	,	,	PUNCT
fnp-3528	565	11	w.	w.	PROPN
fnp-3528	565	12	;	;	PUNCT
fnp-3528	565	13	chiba	chiba	PROPN
fnp-3528	565	14	,	,	PUNCT
fnp-3528	565	15	t.	t.	PROPN
fnp-3528	565	16	;	;	PUNCT
fnp-3528	565	17	onoue	onoue	PROPN
fnp-3528	565	18	,	,	PUNCT
fnp-3528	565	19	h.	h.	PROPN
fnp-3528	565	20	;	;	PUNCT
fnp-3528	565	21	kawamura	kawamura	PROPN
fnp-3528	565	22	,	,	PUNCT
fnp-3528	565	23	y.	y.	PROPN
fnp-3528	565	24	;	;	PUNCT
fnp-3528	565	25	nakayama	nakayama	PROPN
fnp-3528	565	26	,	,	PUNCT
fnp-3528	565	27	a.	a.	NOUN
fnp-3528	565	28	;	;	PUNCT
fnp-3528	565	29	shimizu	shimizu	PROPN
fnp-3528	565	30	,	,	PUNCT
fnp-3528	565	31	s.	s.	PROPN
fnp-3528	565	32	;	;	PUNCT
fnp-3528	565	33	sakiyama	sakiyama	PROPN
fnp-3528	565	34	,	,	PUNCT
fnp-3528	565	35	m.	m.	NOUN
fnp-3528	565	36	;	;	PUNCT
fnp-3528	565	37	funayama	funayama	NOUN
fnp-3528	565	38	,	,	PUNCT
fnp-3528	565	39	m.	m.	NOUN
fnp-3528	565	40	;	;	PUNCT
fnp-3528	565	41	nishioka	nishioka	PROPN
fnp-3528	565	42	,	,	PUNCT
fnp-3528	565	43	k.	k.	PROPN
fnp-3528	565	44	;	;	PUNCT
fnp-3528	565	45	shimizu	shimizu	PROPN
fnp-3528	565	46	,	,	PUNCT
fnp-3528	565	47	t.	t.	PROPN
fnp-3528	565	48	;	;	PUNCT
fnp-3528	565	49	kaida	kaida	PROPN
fnp-3528	565	50	,	,	PUNCT
fnp-3528	565	51	k.	k.	PROPN
fnp-3528	565	52	;	;	PUNCT
fnp-3528	565	53	kamakura	kamakura	PROPN
fnp-3528	565	54	,	,	PUNCT
fnp-3528	565	55	k.	k.	PROPN
fnp-3528	565	56	;	;	PUNCT
fnp-3528	565	57	toda	toda	PROPN
fnp-3528	565	58	,	,	PUNCT
fnp-3528	565	59	t.	t.	PROPN
fnp-3528	565	60	;	;	PUNCT
fnp-3528	565	61	hattori	hattori	PROPN
fnp-3528	565	62	,	,	PUNCT
fnp-3528	565	63	n.	n.	PROPN
fnp-3528	565	64	;	;	PUNCT
fnp-3528	565	65	shinomiya	shinomiya	PROPN
fnp-3528	565	66	,	,	PUNCT
fnp-3528	565	67	n.	n.	PROPN
fnp-3528	565	68	abcg2	abcg2	NOUN
fnp-3528	566	1	variant	variant	NOUN
fnp-3528	566	2	has	have	AUX
fnp-3528	566	3	opposing	oppose	VERB
fnp-3528	566	4	effects	effect	NOUN
fnp-3528	566	5	on	on	ADP
fnp-3528	566	6	onset	onset	ADJ
fnp-3528	566	7	ages	age	NOUN
fnp-3528	566	8	of	of	ADP
fnp-3528	566	9	parkinson	parkinson	NOUN
fnp-3528	566	10	's	's	PART
fnp-3528	566	11	disease	disease	NOUN
fnp-3528	566	12	and	and	CCONJ
fnp-3528	566	13	gout	gout	NOUN
fnp-3528	566	14	.	.	PUNCT
fnp-3528	567	1	ann	ann	PROPN
fnp-3528	567	2	clin	clin	PROPN
fnp-3528	567	3	transl	transl	PROPN
fnp-3528	567	4	neurol	neurol	PROPN
fnp-3528	567	5	2015	2015	NUM
fnp-3528	567	6	,	,	PUNCT
fnp-3528	567	7	2	2	NUM
fnp-3528	567	8	,	,	PUNCT
fnp-3528	567	9	302	302	NUM
fnp-3528	567	10	-	-	SYM
fnp-3528	567	11	6	6	NUM
fnp-3528	567	12	.	.	PUNCT
fnp-3528	568	1	nakato	nakato	PROPN
fnp-3528	568	2	,	,	PUNCT
fnp-3528	568	3	m.	m.	NOUN
fnp-3528	568	4	;	;	PUNCT
fnp-3528	568	5	shiranaga	shiranaga	NOUN
fnp-3528	568	6	,	,	PUNCT
fnp-3528	568	7	n.	n.	NOUN
fnp-3528	568	8	;	;	PUNCT
fnp-3528	568	9	tomioka	tomioka	NOUN
fnp-3528	568	10	,	,	PUNCT
fnp-3528	568	11	m.	m.	NOUN
fnp-3528	568	12	;	;	PUNCT
fnp-3528	568	13	watanabe	watanabe	PROPN
fnp-3528	568	14	,	,	PUNCT
fnp-3528	568	15	h.	h.	PROPN
fnp-3528	568	16	;	;	PUNCT
fnp-3528	568	17	kurisu	kurisu	PROPN
fnp-3528	568	18	,	,	PUNCT
fnp-3528	568	19	j.	j.	PROPN
fnp-3528	568	20	;	;	PUNCT
fnp-3528	568	21	kengaku	kengaku	PROPN
fnp-3528	568	22	,	,	PUNCT
fnp-3528	568	23	m.	m.	NOUN
fnp-3528	568	24	;	;	PUNCT
fnp-3528	568	25	komura	komura	NOUN
fnp-3528	568	26	,	,	PUNCT
fnp-3528	568	27	n.	n.	PROPN
fnp-3528	568	28	;	;	PUNCT
fnp-3528	568	29	ando	ando	PROPN
fnp-3528	568	30	,	,	PUNCT
fnp-3528	568	31	h.	h.	PROPN
fnp-3528	568	32	;	;	PUNCT
fnp-3528	568	33	kimura	kimura	NOUN
fnp-3528	568	34	,	,	PUNCT
fnp-3528	568	35	y.	y.	PROPN
fnp-3528	568	36	;	;	PUNCT
fnp-3528	568	37	kioka	kioka	NOUN
fnp-3528	568	38	,	,	PUNCT
fnp-3528	568	39	n.	n.	NOUN
fnp-3528	568	40	;	;	PUNCT
fnp-3528	568	41	ueda	ueda	PROPN
fnp-3528	568	42	,	,	PUNCT
fnp-3528	568	43	k.	k.	PROPN
fnp-3528	568	44	abca13	abca13	VERB
fnp-3528	568	45	dysfunction	dysfunction	NOUN
fnp-3528	568	46	associated	associate	VERB
fnp-3528	568	47	with	with	ADP
fnp-3528	568	48	psychiatric	psychiatric	ADJ
fnp-3528	568	49	disorders	disorder	NOUN
fnp-3528	568	50	causes	cause	VERB
fnp-3528	568	51	impaired	impaired	ADJ
fnp-3528	568	52	cholesterol	cholesterol	NOUN
fnp-3528	568	53	trafficking	trafficking	NOUN
fnp-3528	568	54	.	.	PUNCT
fnp-3528	569	1	j	j	PROPN
fnp-3528	569	2	biol	biol	PROPN
fnp-3528	569	3	chem	chem	NOUN
fnp-3528	569	4	2020	2020	NUM
fnp-3528	569	5	,	,	PUNCT
fnp-3528	569	6	296	296	NUM
fnp-3528	569	7	,	,	PUNCT
fnp-3528	569	8	100166	100166	NUM
fnp-3528	569	9	.	.	PUNCT
fnp-3528	570	1	dwyer	dwyer	PROPN
fnp-3528	570	2	,	,	PUNCT
fnp-3528	570	3	s.	s.	PROPN
fnp-3528	570	4	;	;	PUNCT
fnp-3528	570	5	williams	williams	PROPN
fnp-3528	570	6	,	,	PUNCT
fnp-3528	570	7	h.	h.	PROPN
fnp-3528	570	8	;	;	PUNCT
fnp-3528	570	9	jones	jones	PROPN
fnp-3528	570	10	,	,	PUNCT
fnp-3528	570	11	i.	i.	PROPN
fnp-3528	570	12	;	;	PUNCT
fnp-3528	570	13	jones	jones	PROPN
fnp-3528	570	14	,	,	PUNCT
fnp-3528	570	15	l.	l.	PROPN
fnp-3528	570	16	;	;	PUNCT
fnp-3528	570	17	walters	walters	PROPN
fnp-3528	570	18	,	,	PUNCT
fnp-3528	570	19	j.	j.	PROPN
fnp-3528	570	20	;	;	PUNCT
fnp-3528	570	21	craddock	craddock	PROPN
fnp-3528	570	22	,	,	PUNCT
fnp-3528	570	23	n.	n.	PROPN
fnp-3528	570	24	;	;	PUNCT
fnp-3528	570	25	owen	owen	PROPN
fnp-3528	570	26	,	,	PUNCT
fnp-3528	570	27	m.	m.	PROPN
fnp-3528	570	28	j.	j.	PROPN
fnp-3528	570	29	;	;	PUNCT
fnp-3528	570	30	o'donovan	o'donovan	PROPN
fnp-3528	570	31	,	,	PUNCT
fnp-3528	570	32	m.	m.	NOUN
fnp-3528	570	33	c.	c.	PROPN
fnp-3528	570	34	investigation	investigation	NOUN
fnp-3528	570	35	of	of	ADP
fnp-3528	570	36	rare	rare	ADJ
fnp-3528	570	37	non	non	ADJ
fnp-3528	570	38	-	-	ADJ
fnp-3528	570	39	synonymous	synonymous	ADJ
fnp-3528	570	40	variants	variant	NOUN
fnp-3528	570	41	at	at	ADP
fnp-3528	570	42	abca13	abca13	NOUN
fnp-3528	570	43	in	in	ADP
fnp-3528	570	44	schizophrenia	schizophrenia	NOUN
fnp-3528	570	45	and	and	CCONJ
fnp-3528	570	46	bipolar	bipolar	ADJ
fnp-3528	570	47	disorder	disorder	NOUN
fnp-3528	570	48	.	.	PUNCT
fnp-3528	571	1	mol	mol	ADP
fnp-3528	571	2	psychiatry	psychiatry	NOUN
fnp-3528	571	3	2011	2011	NUM
fnp-3528	571	4	,	,	PUNCT
fnp-3528	571	5	16	16	NUM
fnp-3528	571	6	,	,	PUNCT
fnp-3528	571	7	790	790	NUM
fnp-3528	571	8	-	-	SYM
fnp-3528	571	9	1	1	NUM
fnp-3528	571	10	.	.	PUNCT
fnp-3528	571	11	nordestgaard	nordestgaard	PROPN
fnp-3528	571	12	,	,	PUNCT
fnp-3528	571	13	l.	l.	PROPN
fnp-3528	571	14	t.	t.	PROPN
fnp-3528	571	15	;	;	PUNCT
fnp-3528	571	16	tybjaerg	tybjaerg	PROPN
fnp-3528	571	17	-	-	PUNCT
fnp-3528	571	18	hansen	hansen	PROPN
fnp-3528	571	19	,	,	PUNCT
fnp-3528	571	20	a.	a.	NOUN
fnp-3528	571	21	;	;	PUNCT
fnp-3528	571	22	nordestgaard	nordestgaard	PROPN
fnp-3528	571	23	,	,	PUNCT
fnp-3528	571	24	b.	b.	PROPN
fnp-3528	571	25	g.	g.	PROPN
fnp-3528	571	26	;	;	PUNCT
fnp-3528	571	27	frikke	frikke	NOUN
fnp-3528	571	28	-	-	PUNCT
fnp-3528	571	29	schmidt	schmidt	NOUN
fnp-3528	571	30	,	,	PUNCT
fnp-3528	571	31	r.	r.	PROPN
fnp-3528	571	32	loss	loss	PROPN
fnp-3528	571	33	-	-	PUNCT
fnp-3528	571	34	of	of	ADP
fnp-3528	571	35	-	-	PUNCT
fnp-3528	571	36	function	function	NOUN
fnp-3528	571	37	mutation	mutation	NOUN
fnp-3528	571	38	in	in	ADP
fnp-3528	571	39	abca1	abca1	NOUN
fnp-3528	571	40	and	and	CCONJ
fnp-3528	571	41	risk	risk	NOUN
fnp-3528	571	42	of	of	ADP
fnp-3528	571	43	alzheimer	alzheimer	PROPN
fnp-3528	571	44	's	's	PART
fnp-3528	571	45	disease	disease	NOUN
fnp-3528	571	46	and	and	CCONJ
fnp-3528	571	47	cerebrovascular	cerebrovascular	ADJ
fnp-3528	571	48	disease	disease	NOUN
fnp-3528	571	49	.	.	PUNCT
fnp-3528	572	1	alzheimers	alzheimers	PROPN
fnp-3528	572	2	dement	dement	PROPN
fnp-3528	572	3	2015	2015	NUM
fnp-3528	572	4	,	,	PUNCT
fnp-3528	572	5	11	11	NUM
fnp-3528	572	6	,	,	PUNCT
fnp-3528	572	7	1430	1430	NUM
fnp-3528	572	8	-	-	SYM
fnp-3528	572	9	8	8	NUM
fnp-3528	572	10	.	.	PUNCT
fnp-3528	573	1	gonzalez	gonzalez	PROPN
fnp-3528	573	2	-	-	PUNCT
fnp-3528	573	3	guevara	guevara	PROPN
fnp-3528	573	4	,	,	PUNCT
fnp-3528	573	5	e.	e.	PROPN
fnp-3528	573	6	;	;	PUNCT
fnp-3528	573	7	cardenas	cardenas	PROPN
fnp-3528	573	8	,	,	PUNCT
fnp-3528	573	9	g.	g.	PROPN
fnp-3528	573	10	;	;	PUNCT
fnp-3528	573	11	perez	perez	PROPN
fnp-3528	573	12	-	-	PUNCT
fnp-3528	573	13	severiano	severiano	PROPN
fnp-3528	573	14	,	,	PUNCT
fnp-3528	573	15	f.	f.	PROPN
fnp-3528	573	16	;	;	PUNCT
fnp-3528	573	17	martinez	martinez	PROPN
fnp-3528	573	18	-	-	PUNCT
fnp-3528	573	19	lazcano	lazcano	PROPN
fnp-3528	573	20	,	,	PUNCT
fnp-3528	573	21	j.	j.	PROPN
fnp-3528	573	22	c.	c.	PROPN
fnp-3528	573	23	dysregulated	dysregulate	VERB
fnp-3528	573	24	brain	brain	NOUN
fnp-3528	573	25	cholesterol	cholesterol	NOUN
fnp-3528	573	26	metabolism	metabolism	NOUN
fnp-3528	573	27	is	be	AUX
fnp-3528	573	28	linked	link	VERB
fnp-3528	573	29	to	to	ADP
fnp-3528	573	30	neuroinflammation	neuroinflammation	NOUN
fnp-3528	573	31	in	in	ADP
fnp-3528	573	32	huntington	huntington	PROPN
fnp-3528	573	33	's	's	PART
fnp-3528	573	34	disease	disease	NOUN
fnp-3528	573	35	.	.	PUNCT
fnp-3528	574	1	mov	mov	NOUN
fnp-3528	574	2	disord	disord	NOUN
fnp-3528	574	3	2020	2020	NUM
fnp-3528	574	4	,	,	PUNCT
fnp-3528	574	5	35	35	NUM
fnp-3528	574	6	,	,	PUNCT
fnp-3528	574	7	1113	1113	NUM
fnp-3528	574	8	-	-	SYM
fnp-3528	574	9	27	27	NUM
fnp-3528	574	10	.	.	PUNCT
fnp-3528	575	1	macé	macé	PROPN
fnp-3528	575	2	,	,	PUNCT
fnp-3528	575	3	s.	s.	PROPN
fnp-3528	575	4	;	;	PUNCT
fnp-3528	575	5	cousin	cousin	PROPN
fnp-3528	575	6	,	,	PUNCT
fnp-3528	575	7	e.	e.	PROPN
fnp-3528	575	8	;	;	PUNCT
fnp-3528	575	9	ricard	ricard	PROPN
fnp-3528	575	10	,	,	PUNCT
fnp-3528	575	11	s.	s.	PROPN
fnp-3528	575	12	;	;	PUNCT
fnp-3528	575	13	génin	génin	PROPN
fnp-3528	575	14	,	,	PUNCT
fnp-3528	575	15	e.	e.	PROPN
fnp-3528	575	16	;	;	PUNCT
fnp-3528	575	17	spanakis	spanakis	PROPN
fnp-3528	575	18	,	,	PUNCT
fnp-3528	575	19	e.	e.	PROPN
fnp-3528	575	20	;	;	PUNCT
fnp-3528	575	21	lafargue	lafargue	NOUN
fnp-3528	575	22	-	-	PUNCT
fnp-3528	575	23	soubigou	soubigou	NOUN
fnp-3528	575	24	,	,	PUNCT
fnp-3528	575	25	c.	c.	NOUN
fnp-3528	575	26	;	;	PUNCT
fnp-3528	575	27	génin	génin	PROPN
fnp-3528	575	28	,	,	PUNCT
fnp-3528	575	29	b.	b.	PROPN
fnp-3528	575	30	;	;	PUNCT
fnp-3528	575	31	fournel	fournel	PROPN
fnp-3528	575	32	,	,	PUNCT
fnp-3528	575	33	r.	r.	PROPN
fnp-3528	575	34	;	;	PUNCT
fnp-3528	575	35	roche	roche	PROPN
fnp-3528	575	36	,	,	PUNCT
fnp-3528	575	37	s.	s.	PROPN
fnp-3528	575	38	;	;	PUNCT
fnp-3528	575	39	haussy	haussy	PROPN
fnp-3528	575	40	,	,	PUNCT
fnp-3528	575	41	g.	g.	PROPN
fnp-3528	575	42	;	;	PUNCT
fnp-3528	575	43	massey	massey	PROPN
fnp-3528	575	44	,	,	PUNCT
fnp-3528	575	45	f.	f.	PROPN
fnp-3528	575	46	;	;	PUNCT
fnp-3528	575	47	soubigou	soubigou	PROPN
fnp-3528	575	48	,	,	PUNCT
fnp-3528	575	49	s.	s.	PROPN
fnp-3528	575	50	;	;	PUNCT
fnp-3528	575	51	bréfort	bréfort	PROPN
fnp-3528	575	52	,	,	PUNCT
fnp-3528	575	53	g.	g.	PROPN
fnp-3528	575	54	;	;	PUNCT
fnp-3528	575	55	benoit	benoit	NOUN
fnp-3528	575	56	,	,	PUNCT
fnp-3528	575	57	p.	p.	PROPN
fnp-3528	575	58	;	;	PUNCT
fnp-3528	575	59	brice	brice	PROPN
fnp-3528	575	60	,	,	PUNCT
fnp-3528	575	61	a.	a.	NOUN
fnp-3528	575	62	;	;	PUNCT
fnp-3528	575	63	campion	campion	NOUN
fnp-3528	575	64	,	,	PUNCT
fnp-3528	575	65	d.	d.	PROPN
fnp-3528	575	66	;	;	PUNCT
fnp-3528	575	67	hollis	hollis	PROPN
fnp-3528	575	68	,	,	PUNCT
fnp-3528	575	69	m.	m.	NOUN
fnp-3528	575	70	;	;	PUNCT
fnp-3528	575	71	pradier	pradier	NOUN
fnp-3528	575	72	,	,	PUNCT
fnp-3528	575	73	l.	l.	PROPN
fnp-3528	575	74	;	;	PUNCT
fnp-3528	575	75	benavides	benavides	PROPN
fnp-3528	575	76	,	,	PUNCT
fnp-3528	575	77	j.	j.	PROPN
fnp-3528	575	78	;	;	PUNCT
fnp-3528	575	79	deleuze	deleuze	PROPN
fnp-3528	575	80	,	,	PUNCT
fnp-3528	576	1	j.	j.	PROPN
fnp-3528	576	2	f.	f.	PROPN
fnp-3528	576	3	abca2	abca2	PROPN
fnp-3528	576	4	is	be	AUX
fnp-3528	576	5	a	a	DET
fnp-3528	576	6	strong	strong	ADJ
fnp-3528	576	7	genetic	genetic	ADJ
fnp-3528	576	8	risk	risk	NOUN
fnp-3528	576	9	factor	factor	NOUN
fnp-3528	576	10	for	for	ADP
fnp-3528	576	11	early	early	ADJ
fnp-3528	576	12	-	-	PUNCT
fnp-3528	576	13	onset	onset	NOUN
fnp-3528	576	14	alzheimer	alzheimer	NOUN
fnp-3528	576	15	's	's	PART
fnp-3528	576	16	disease	disease	NOUN
fnp-3528	576	17	.	.	PUNCT
fnp-3528	577	1	neurobiol	neurobiol	PROPN
fnp-3528	577	2	dis	dis	PROPN
fnp-3528	577	3	2005	2005	NUM
fnp-3528	577	4	,	,	PUNCT
fnp-3528	577	5	18	18	NUM
fnp-3528	577	6	,	,	PUNCT
fnp-3528	577	7	119	119	NUM
fnp-3528	577	8	-	-	SYM
fnp-3528	577	9	25	25	NUM
fnp-3528	577	10	.	.	PUNCT
fnp-3528	578	1	davis	davis	PROPN
fnp-3528	578	2	,	,	PUNCT
fnp-3528	578	3	w.	w.	PROPN
fnp-3528	578	4	,	,	PUNCT
fnp-3528	578	5	jr	jr	PROPN
fnp-3528	578	6	.	.	PUNCT
fnp-3528	579	1	the	the	DET
fnp-3528	579	2	atp	atp	NOUN
fnp-3528	579	3	-	-	PUNCT
fnp-3528	579	4	binding	bind	VERB
fnp-3528	579	5	cassette	cassette	NOUN
fnp-3528	579	6	transporter-2	transporter-2	NUM
fnp-3528	579	7	(	(	PUNCT
fnp-3528	579	8	abca2	abca2	PROPN
fnp-3528	579	9	)	)	PUNCT
fnp-3528	579	10	regulates	regulate	VERB
fnp-3528	579	11	esterification	esterification	NOUN
fnp-3528	579	12	of	of	ADP
fnp-3528	579	13	plasma	plasma	NOUN
fnp-3528	579	14	membrane	membrane	NOUN
fnp-3528	579	15	cholesterol	cholesterol	NOUN
fnp-3528	579	16	by	by	ADP
fnp-3528	579	17	modulation	modulation	NOUN
fnp-3528	579	18	of	of	ADP
fnp-3528	579	19	sphingolipid	sphingolipid	PROPN
fnp-3528	579	20	metabolism	metabolism	NOUN
fnp-3528	579	21	.	.	PUNCT
fnp-3528	580	1	biochim	biochim	PROPN
fnp-3528	580	2	biophys	biophy	NOUN
fnp-3528	580	3	acta	acta	PROPN
fnp-3528	580	4	2014	2014	NUM
fnp-3528	580	5	,	,	PUNCT
fnp-3528	580	6	1841	1841	NUM
fnp-3528	580	7	,	,	PUNCT
fnp-3528	580	8	168	168	NUM
fnp-3528	580	9	-	-	SYM
fnp-3528	580	10	79	79	NUM
fnp-3528	580	11	.	.	PUNCT
fnp-3528	581	1	sakai	sakai	PROPN
fnp-3528	581	2	,	,	PUNCT
fnp-3528	581	3	h.	h.	PROPN
fnp-3528	581	4	;	;	PUNCT
fnp-3528	581	5	tanaka	tanaka	PROPN
fnp-3528	581	6	,	,	PUNCT
fnp-3528	581	7	y.	y.	PROPN
fnp-3528	581	8	;	;	PUNCT
fnp-3528	581	9	tanaka	tanaka	PROPN
fnp-3528	581	10	,	,	PUNCT
fnp-3528	581	11	m.	m.	NOUN
fnp-3528	581	12	;	;	PUNCT
fnp-3528	581	13	ban	ban	NOUN
fnp-3528	581	14	,	,	PUNCT
fnp-3528	581	15	n.	n.	PROPN
fnp-3528	581	16	;	;	PUNCT
fnp-3528	581	17	yamada	yamada	PROPN
fnp-3528	581	18	,	,	PUNCT
fnp-3528	581	19	k.	k.	PROPN
fnp-3528	581	20	;	;	PUNCT
fnp-3528	581	21	matsumura	matsumura	ADV
fnp-3528	581	22	,	,	PUNCT
fnp-3528	581	23	y.	y.	PROPN
fnp-3528	581	24	;	;	PUNCT
fnp-3528	581	25	watanabe	watanabe	PROPN
fnp-3528	581	26	,	,	PUNCT
fnp-3528	581	27	d.	d.	PROPN
fnp-3528	581	28	;	;	PUNCT
fnp-3528	581	29	sasaki	sasaki	PROPN
fnp-3528	581	30	,	,	PUNCT
fnp-3528	581	31	m.	m.	NOUN
fnp-3528	581	32	;	;	PUNCT
fnp-3528	581	33	kita	kita	PROPN
fnp-3528	581	34	,	,	PUNCT
fnp-3528	581	35	t.	t.	PROPN
fnp-3528	581	36	;	;	PUNCT
fnp-3528	581	37	inagaki	inagaki	PROPN
fnp-3528	581	38	,	,	PUNCT
fnp-3528	581	39	n.	n.	NOUN
fnp-3528	581	40	abca2	abca2	NOUN
fnp-3528	581	41	deficiency	deficiency	NOUN
fnp-3528	581	42	results	result	NOUN
fnp-3528	581	43	in	in	ADP
fnp-3528	581	44	abnormal	abnormal	ADJ
fnp-3528	581	45	sphingolipid	sphingolipid	NOUN
fnp-3528	581	46	metabolism	metabolism	NOUN
fnp-3528	581	47	in	in	ADP
fnp-3528	581	48	mouse	mouse	NOUN
fnp-3528	581	49	brain	brain	NOUN
fnp-3528	581	50	.	.	PUNCT
fnp-3528	582	1	j	j	PROPN
fnp-3528	582	2	biol	biol	PROPN
fnp-3528	582	3	chem	chem	NOUN
fnp-3528	582	4	2007	2007	NUM
fnp-3528	582	5	,	,	PUNCT
fnp-3528	582	6	282	282	NUM
fnp-3528	582	7	,	,	PUNCT
fnp-3528	582	8	19692	19692	NUM
fnp-3528	582	9	-	-	SYM
fnp-3528	582	10	9	9	NUM
fnp-3528	582	11	.	.	PUNCT
fnp-3528	582	12	maugeri	maugeri	NOUN
fnp-3528	582	13	,	,	PUNCT
fnp-3528	582	14	a.	a.	NOUN
fnp-3528	582	15	;	;	PUNCT
fnp-3528	582	16	klevering	klevere	VERB
fnp-3528	582	17	,	,	PUNCT
fnp-3528	582	18	b.	b.	PROPN
fnp-3528	582	19	j.	j.	PROPN
fnp-3528	582	20	;	;	PUNCT
fnp-3528	582	21	rohrschneider	rohrschneider	NOUN
fnp-3528	582	22	,	,	PUNCT
fnp-3528	582	23	k.	k.	PROPN
fnp-3528	582	24	;	;	PUNCT
fnp-3528	582	25	blankenagel	blankenagel	NOUN
fnp-3528	582	26	,	,	PUNCT
fnp-3528	582	27	a.	a.	NOUN
fnp-3528	582	28	;	;	PUNCT
fnp-3528	582	29	brunner	brunner	PROPN
fnp-3528	582	30	,	,	PUNCT
fnp-3528	582	31	h.	h.	PROPN
fnp-3528	582	32	g.	g.	PROPN
fnp-3528	582	33	;	;	PUNCT
fnp-3528	582	34	deutman	deutman	NOUN
fnp-3528	582	35	,	,	PUNCT
fnp-3528	582	36	a.	a.	PROPN
fnp-3528	582	37	f.	f.	PROPN
fnp-3528	582	38	;	;	PUNCT
fnp-3528	582	39	hoyng	hoyng	PRON
fnp-3528	582	40	,	,	PUNCT
fnp-3528	582	41	c.	c.	PROPN
fnp-3528	582	42	b.	b.	PROPN
fnp-3528	582	43	;	;	PUNCT
fnp-3528	582	44	cremers	cremer	NOUN
fnp-3528	582	45	,	,	PUNCT
fnp-3528	583	1	f.	f.	PROPN
fnp-3528	583	2	p.	p.	PROPN
fnp-3528	583	3	mutations	mutation	NOUN
fnp-3528	583	4	in	in	ADP
fnp-3528	583	5	the	the	DET
fnp-3528	583	6	abca4	abca4	PROPN
fnp-3528	583	7	(	(	PUNCT
fnp-3528	583	8	abcr	abcr	NOUN
fnp-3528	583	9	)	)	PUNCT
fnp-3528	583	10	gene	gene	NOUN
fnp-3528	583	11	are	be	AUX
fnp-3528	583	12	the	the	DET
fnp-3528	583	13	major	major	ADJ
fnp-3528	583	14	cause	cause	NOUN
fnp-3528	583	15	of	of	ADP
fnp-3528	583	16	autosomal	autosomal	ADJ
fnp-3528	583	17	recessive	recessive	ADJ
fnp-3528	583	18	cone	cone	NOUN
fnp-3528	583	19	-	-	PUNCT
fnp-3528	583	20	rod	rod	NOUN
fnp-3528	583	21	dystrophy	dystrophy	NOUN
fnp-3528	583	22	.	.	PUNCT
fnp-3528	584	1	am	be	AUX
fnp-3528	584	2	j	j	PROPN
fnp-3528	584	3	hum	hum	PROPN
fnp-3528	584	4	genet	genet	PROPN
fnp-3528	584	5	2000	2000	NUM
fnp-3528	584	6	,	,	PUNCT
fnp-3528	584	7	67	67	NUM
fnp-3528	584	8	,	,	PUNCT
fnp-3528	584	9	960	960	NUM
fnp-3528	584	10	-	-	SYM
fnp-3528	584	11	6	6	NUM
fnp-3528	584	12	.	.	PUNCT
fnp-3528	585	1	cremers	cremer	NOUN
fnp-3528	585	2	,	,	PUNCT
fnp-3528	585	3	f.	f.	PROPN
fnp-3528	585	4	p.	p.	PROPN
fnp-3528	585	5	m.	m.	NOUN
fnp-3528	585	6	;	;	PUNCT
fnp-3528	585	7	lee	lee	PROPN
fnp-3528	585	8	,	,	PUNCT
fnp-3528	585	9	w.	w.	PROPN
fnp-3528	585	10	;	;	PUNCT
fnp-3528	585	11	collin	collin	PROPN
fnp-3528	585	12	,	,	PUNCT
fnp-3528	585	13	r.	r.	PROPN
fnp-3528	585	14	w.	w.	PROPN
fnp-3528	585	15	j.	j.	PROPN
fnp-3528	585	16	;	;	PUNCT
fnp-3528	585	17	allikmets	allikmet	NOUN
fnp-3528	585	18	,	,	PUNCT
fnp-3528	585	19	r.	r.	PROPN
fnp-3528	585	20	clinical	clinical	PROPN
fnp-3528	585	21	spectrum	spectrum	PROPN
fnp-3528	585	22	,	,	PUNCT
fnp-3528	585	23	genetic	genetic	ADJ
fnp-3528	585	24	complexity	complexity	NOUN
fnp-3528	585	25	and	and	CCONJ
fnp-3528	585	26	therapeutic	therapeutic	ADJ
fnp-3528	585	27	approaches	approach	NOUN
fnp-3528	585	28	for	for	ADP
fnp-3528	585	29	retinal	retinal	ADJ
fnp-3528	585	30	disease	disease	NOUN
fnp-3528	585	31	caused	cause	VERB
fnp-3528	585	32	by	by	ADP
fnp-3528	585	33	abca4	abca4	ADJ
fnp-3528	585	34	mutations	mutation	NOUN
fnp-3528	585	35	.	.	PUNCT
fnp-3528	586	1	prog	prog	PROPN
fnp-3528	586	2	retin	retin	PROPN
fnp-3528	586	3	eye	eye	PROPN
fnp-3528	586	4	res	re	NOUN
fnp-3528	586	5	2020	2020	NUM
fnp-3528	586	6	,	,	PUNCT
fnp-3528	586	7	79	79	NUM
fnp-3528	586	8	,	,	PUNCT
fnp-3528	586	9	100861	100861	NUM
fnp-3528	586	10	.	.	PUNCT
fnp-3528	587	1	cremers	cremer	NOUN
fnp-3528	587	2	,	,	PUNCT
fnp-3528	587	3	f.	f.	PROPN
fnp-3528	587	4	p.	p.	PROPN
fnp-3528	587	5	;	;	PUNCT
fnp-3528	587	6	van	van	PROPN
fnp-3528	587	7	de	de	PROPN
fnp-3528	587	8	pol	pol	PROPN
fnp-3528	587	9	,	,	PUNCT
fnp-3528	587	10	d.	d.	PROPN
fnp-3528	587	11	j.	j.	PROPN
fnp-3528	587	12	;	;	PUNCT
fnp-3528	587	13	van	van	PROPN
fnp-3528	587	14	driel	driel	NOUN
fnp-3528	587	15	,	,	PUNCT
fnp-3528	587	16	m.	m.	NOUN
fnp-3528	587	17	;	;	PUNCT
fnp-3528	587	18	den	den	PROPN
fnp-3528	587	19	hollander	hollander	PROPN
fnp-3528	587	20	,	,	PUNCT
fnp-3528	587	21	a.	a.	NOUN
fnp-3528	587	22	i.	i.	PROPN
fnp-3528	587	23	;	;	PUNCT
fnp-3528	587	24	van	van	PROPN
fnp-3528	587	25	haren	haren	PROPN
fnp-3528	587	26	,	,	PUNCT
fnp-3528	587	27	f.	f.	PROPN
fnp-3528	587	28	j.	j.	PROPN
fnp-3528	587	29	;	;	PUNCT
fnp-3528	587	30	knoers	knoer	NOUN
fnp-3528	587	31	,	,	PUNCT
fnp-3528	587	32	n.	n.	PROPN
fnp-3528	587	33	v.	v.	PROPN
fnp-3528	587	34	;	;	PUNCT
fnp-3528	587	35	tijmes	tijme	NOUN
fnp-3528	587	36	,	,	PUNCT
fnp-3528	587	37	n.	n.	NOUN
fnp-3528	587	38	;	;	PUNCT
fnp-3528	587	39	bergen	bergen	PROPN
fnp-3528	587	40	,	,	PUNCT
fnp-3528	587	41	a.	a.	NOUN
fnp-3528	587	42	a.	a.	PROPN
fnp-3528	587	43	;	;	PUNCT
fnp-3528	587	44	rohrschneider	rohrschneider	NOUN
fnp-3528	587	45	,	,	PUNCT
fnp-3528	587	46	k.	k.	PROPN
fnp-3528	587	47	;	;	PUNCT
fnp-3528	587	48	blankenagel	blankenagel	PROPN
fnp-3528	587	49	,	,	PUNCT
fnp-3528	587	50	a.	a.	NOUN
fnp-3528	587	51	;	;	PUNCT
fnp-3528	587	52	pinckers	pincker	NOUN
fnp-3528	587	53	,	,	PUNCT
fnp-3528	587	54	a.	a.	PROPN
fnp-3528	587	55	j.	j.	PROPN
fnp-3528	587	56	;	;	PUNCT
fnp-3528	587	57	deutman	deutman	NOUN
fnp-3528	587	58	,	,	PUNCT
fnp-3528	587	59	a.	a.	PROPN
fnp-3528	587	60	f.	f.	PROPN
fnp-3528	587	61	;	;	PUNCT
fnp-3528	587	62	hoyng	hoyng	PRON
fnp-3528	587	63	,	,	PUNCT
fnp-3528	587	64	c.	c.	PROPN
fnp-3528	587	65	b.	b.	PROPN
fnp-3528	588	1	autosomal	autosomal	ADJ
fnp-3528	588	2	recessive	recessive	ADJ
fnp-3528	588	3	retinitis	retinitis	ADJ
fnp-3528	588	4	pigmentosa	pigmentosa	NOUN
fnp-3528	588	5	and	and	CCONJ
fnp-3528	588	6	cone	cone	NOUN
fnp-3528	588	7	-	-	PUNCT
fnp-3528	588	8	rod	rod	NOUN
fnp-3528	588	9	dystrophy	dystrophy	NOUN
fnp-3528	588	10	caused	cause	VERB
fnp-3528	588	11	by	by	ADP
fnp-3528	588	12	splice	splice	NOUN
fnp-3528	588	13	site	site	NOUN
fnp-3528	588	14	mutations	mutation	NOUN
fnp-3528	588	15	in	in	ADP
fnp-3528	588	16	the	the	DET
fnp-3528	588	17	stargardt	stargardt	NOUN
fnp-3528	588	18	's	's	PART
fnp-3528	588	19	disease	disease	NOUN
fnp-3528	588	20	gene	gene	NOUN
fnp-3528	588	21	abcr	abcr	VERB
fnp-3528	588	22	.	.	PUNCT
fnp-3528	589	1	hum	hum	PROPN
fnp-3528	589	2	mol	mol	ADP
fnp-3528	589	3	genet	genet	PROPN
fnp-3528	589	4	1998	1998	NUM
fnp-3528	589	5	,	,	PUNCT
fnp-3528	589	6	7	7	NUM
fnp-3528	589	7	,	,	PUNCT
fnp-3528	589	8	355	355	NUM
fnp-3528	589	9	-	-	SYM
fnp-3528	589	10	62	62	NUM
fnp-3528	589	11	.	.	PUNCT
fnp-3528	590	1	martínez	martínez	NOUN
fnp-3528	590	2	-	-	PUNCT
fnp-3528	590	3	mir	mir	PROPN
fnp-3528	590	4	,	,	PUNCT
fnp-3528	590	5	a.	a.	NOUN
fnp-3528	590	6	;	;	PUNCT
fnp-3528	590	7	paloma	paloma	PROPN
fnp-3528	590	8	,	,	PUNCT
fnp-3528	590	9	e.	e.	PROPN
fnp-3528	590	10	;	;	PUNCT
fnp-3528	590	11	allikmets	allikmet	NOUN
fnp-3528	590	12	,	,	PUNCT
fnp-3528	590	13	r.	r.	PROPN
fnp-3528	590	14	;	;	PUNCT
fnp-3528	590	15	ayuso	ayuso	PROPN
fnp-3528	590	16	,	,	PUNCT
fnp-3528	590	17	c.	c.	PROPN
fnp-3528	590	18	;	;	PUNCT
fnp-3528	590	19	del	del	PROPN
fnp-3528	590	20	rio	rio	PROPN
fnp-3528	590	21	,	,	PUNCT
fnp-3528	590	22	t.	t.	PROPN
fnp-3528	590	23	;	;	PUNCT
fnp-3528	590	24	dean	dean	PROPN
fnp-3528	590	25	,	,	PUNCT
fnp-3528	590	26	m.	m.	NOUN
fnp-3528	590	27	;	;	PUNCT
fnp-3528	590	28	vilageliu	vilageliu	PROPN
fnp-3528	590	29	,	,	PUNCT
fnp-3528	590	30	l.	l.	PROPN
fnp-3528	590	31	;	;	PUNCT
fnp-3528	590	32	gonzàlez	gonzàlez	PROPN
fnp-3528	590	33	-	-	PUNCT
fnp-3528	590	34	duarte	duarte	PROPN
fnp-3528	590	35	,	,	PUNCT
fnp-3528	590	36	r.	r.	PROPN
fnp-3528	590	37	;	;	PUNCT
fnp-3528	590	38	balcells	balcell	NOUN
fnp-3528	590	39	,	,	PUNCT
fnp-3528	590	40	s.	s.	PROPN
fnp-3528	590	41	retinitis	retinitis	PROPN
fnp-3528	590	42	pigmentosa	pigmentosa	PROPN
fnp-3528	590	43	caused	cause	VERB
fnp-3528	590	44	by	by	ADP
fnp-3528	590	45	a	a	DET
fnp-3528	590	46	homozygous	homozygous	ADJ
fnp-3528	590	47	mutation	mutation	NOUN
fnp-3528	590	48	in	in	ADP
fnp-3528	590	49	the	the	DET
fnp-3528	590	50	stargardt	stargardt	ADJ
fnp-3528	590	51	disease	disease	NOUN
fnp-3528	590	52	gene	gene	NOUN
fnp-3528	590	53	abcr	abcr	VERB
fnp-3528	590	54	.	.	PUNCT
fnp-3528	591	1	nat	nat	PROPN
fnp-3528	591	2	genet	genet	PROPN
fnp-3528	591	3	1998	1998	NUM
fnp-3528	591	4	,	,	PUNCT
fnp-3528	591	5	18	18	NUM
fnp-3528	591	6	,	,	PUNCT
fnp-3528	591	7	11	11	NUM
fnp-3528	591	8	-	-	SYM
fnp-3528	591	9	2	2	NUM
fnp-3528	591	10	.	.	PUNCT
fnp-3528	592	1	srisuwanwattana	srisuwanwattana	PROPN
fnp-3528	592	2	,	,	PUNCT
fnp-3528	592	3	p.	p.	NOUN
fnp-3528	592	4	;	;	PUNCT
fnp-3528	592	5	vachiramon	vachiramon	NOUN
fnp-3528	592	6	,	,	PUNCT
fnp-3528	592	7	v.	v.	ADP
fnp-3528	592	8	necrolytic	necrolytic	ADJ
fnp-3528	592	9	acral	acral	ADJ
fnp-3528	592	10	erythema	erythema	NOUN
fnp-3528	592	11	in	in	ADP
fnp-3528	592	12	seronegative	seronegative	ADJ
fnp-3528	592	13	hepatitis	hepatitis	PROPN
fnp-3528	592	14	c.	c.	PROPN
fnp-3528	592	15	case	case	NOUN
fnp-3528	592	16	rep	rep	PROPN
fnp-3528	592	17	dermatol	dermatol	NOUN
fnp-3528	592	18	2017	2017	NUM
fnp-3528	592	19	,	,	PUNCT
fnp-3528	592	20	9	9	NUM
fnp-3528	592	21	,	,	PUNCT
fnp-3528	592	22	69	69	NUM
fnp-3528	592	23	-	-	SYM
fnp-3528	592	24	73	73	NUM
fnp-3528	592	25	.	.	PUNCT
fnp-3528	593	1	conley	conley	PROPN
fnp-3528	593	2	,	,	PUNCT
fnp-3528	593	3	s.	s.	PROPN
fnp-3528	593	4	m.	m.	PROPN
fnp-3528	593	5	;	;	PUNCT
fnp-3528	593	6	cai	cai	X
fnp-3528	593	7	,	,	PUNCT
fnp-3528	593	8	x.	x.	NOUN
fnp-3528	593	9	;	;	PUNCT
fnp-3528	593	10	makkia	makkia	NOUN
fnp-3528	593	11	,	,	PUNCT
fnp-3528	593	12	r.	r.	PROPN
fnp-3528	593	13	;	;	PUNCT
fnp-3528	593	14	wu	wu	PROPN
fnp-3528	593	15	,	,	PUNCT
fnp-3528	593	16	y.	y.	PROPN
fnp-3528	593	17	;	;	PUNCT
fnp-3528	593	18	sparrow	sparrow	PROPN
fnp-3528	593	19	,	,	PUNCT
fnp-3528	593	20	j.	j.	PROPN
fnp-3528	593	21	r.	r.	PROPN
fnp-3528	593	22	;	;	PUNCT
fnp-3528	593	23	naash	naash	NOUN
fnp-3528	593	24	,	,	PUNCT
fnp-3528	593	25	m.	m.	NOUN
fnp-3528	593	26	i.	i.	PROPN
fnp-3528	593	27	increased	increase	VERB
fnp-3528	593	28	cone	cone	NOUN
fnp-3528	593	29	sensitivity	sensitivity	NOUN
fnp-3528	593	30	to	to	PART
fnp-3528	593	31	abca4	abca4	VERB
fnp-3528	593	32	deficiency	deficiency	NOUN
fnp-3528	593	33	provides	provide	VERB
fnp-3528	593	34	insight	insight	NOUN
fnp-3528	593	35	into	into	ADP
fnp-3528	593	36	macular	macular	ADJ
fnp-3528	593	37	vision	vision	NOUN
fnp-3528	593	38	loss	loss	NOUN
fnp-3528	593	39	in	in	ADP
fnp-3528	593	40	stargardt	stargardt	PROPN
fnp-3528	593	41	's	's	PART
fnp-3528	593	42	dystrophy	dystrophy	NOUN
fnp-3528	593	43	.	.	PUNCT
fnp-3528	594	1	biochim	biochim	PROPN
fnp-3528	594	2	biophys	biophy	NOUN
fnp-3528	594	3	acta	acta	PROPN
fnp-3528	594	4	2012	2012	NUM
fnp-3528	594	5	,	,	PUNCT
fnp-3528	594	6	1822	1822	NUM
fnp-3528	594	7	,	,	PUNCT
fnp-3528	594	8	1169	1169	NUM
fnp-3528	594	9	-	-	SYM
fnp-3528	594	10	79	79	NUM
fnp-3528	594	11	.	.	PUNCT
fnp-3528	595	1	cideciyan	cideciyan	ADJ
fnp-3528	595	2	,	,	PUNCT
fnp-3528	595	3	a.	a.	NOUN
fnp-3528	595	4	v.	v.	PROPN
fnp-3528	595	5	;	;	PUNCT
fnp-3528	595	6	aleman	aleman	PROPN
fnp-3528	595	7	,	,	PUNCT
fnp-3528	595	8	t.	t.	PROPN
fnp-3528	595	9	s.	s.	PROPN
fnp-3528	595	10	;	;	PUNCT
fnp-3528	595	11	swider	swider	NOUN
fnp-3528	595	12	,	,	PUNCT
fnp-3528	595	13	m.	m.	NOUN
fnp-3528	595	14	;	;	PUNCT
fnp-3528	595	15	schwartz	schwartz	PROPN
fnp-3528	595	16	,	,	PUNCT
fnp-3528	595	17	s.	s.	PROPN
fnp-3528	595	18	b.	b.	PROPN
fnp-3528	595	19	;	;	PUNCT
fnp-3528	595	20	steinberg	steinberg	PROPN
fnp-3528	595	21	,	,	PUNCT
fnp-3528	595	22	j.	j.	PROPN
fnp-3528	595	23	d.	d.	PROPN
fnp-3528	595	24	;	;	PUNCT
fnp-3528	595	25	brucker	brucker	NOUN
fnp-3528	595	26	,	,	PUNCT
fnp-3528	595	27	a.	a.	PROPN
fnp-3528	595	28	j.	j.	PROPN
fnp-3528	595	29	;	;	PUNCT
fnp-3528	595	30	maguire	maguire	PROPN
fnp-3528	595	31	,	,	PUNCT
fnp-3528	595	32	a.	a.	NOUN
fnp-3528	595	33	m.	m.	NOUN
fnp-3528	595	34	;	;	PUNCT
fnp-3528	595	35	bennett	bennett	PROPN
fnp-3528	595	36	,	,	PUNCT
fnp-3528	595	37	j.	j.	PROPN
fnp-3528	595	38	;	;	PUNCT
fnp-3528	595	39	stone	stone	PROPN
fnp-3528	595	40	,	,	PUNCT
fnp-3528	595	41	e.	e.	PROPN
fnp-3528	595	42	m.	m.	PROPN
fnp-3528	595	43	;	;	PUNCT
fnp-3528	595	44	jacobson	jacobson	PROPN
fnp-3528	595	45	,	,	PUNCT
fnp-3528	595	46	s.	s.	PROPN
fnp-3528	595	47	g.	g.	PROPN
fnp-3528	595	48	mutations	mutation	NOUN
fnp-3528	595	49	in	in	ADP
fnp-3528	595	50	abca4	abca4	PROPN
fnp-3528	595	51	result	result	NOUN
fnp-3528	595	52	in	in	ADP
fnp-3528	595	53	accumulation	accumulation	NOUN
fnp-3528	595	54	of	of	ADP
fnp-3528	595	55	lipofuscin	lipofuscin	NOUN
fnp-3528	595	56	before	before	ADP
fnp-3528	595	57	slowing	slow	VERB
fnp-3528	595	58	of	of	ADP
fnp-3528	595	59	the	the	DET
fnp-3528	595	60	retinoid	retinoid	PROPN
fnp-3528	595	61	cycle	cycle	NOUN
fnp-3528	595	62	:	:	PUNCT
fnp-3528	595	63	a	a	DET
fnp-3528	595	64	reappraisal	reappraisal	NOUN
fnp-3528	595	65	of	of	ADP
fnp-3528	595	66	the	the	DET
fnp-3528	595	67	human	human	ADJ
fnp-3528	595	68	disease	disease	NOUN
fnp-3528	595	69	sequence	sequence	NOUN
fnp-3528	595	70	.	.	PUNCT
fnp-3528	596	1	hum	hum	PROPN
fnp-3528	596	2	mol	mol	ADP
fnp-3528	596	3	genet	genet	PROPN
fnp-3528	596	4	2004	2004	NUM
fnp-3528	596	5	,	,	PUNCT
fnp-3528	596	6	13	13	NUM
fnp-3528	596	7	,	,	PUNCT
fnp-3528	596	8	525	525	NUM
fnp-3528	596	9	-	-	SYM
fnp-3528	596	10	34	34	NUM
fnp-3528	596	11	.	.	PUNCT
fnp-3528	597	1	allikmets	allikmet	NOUN
fnp-3528	597	2	,	,	PUNCT
fnp-3528	597	3	r.	r.	NOUN
fnp-3528	597	4	a	a	DET
fnp-3528	597	5	photoreceptor	photoreceptor	NOUN
fnp-3528	597	6	cell	cell	NOUN
fnp-3528	597	7	-	-	PUNCT
fnp-3528	597	8	specific	specific	ADJ
fnp-3528	597	9	atp	atp	NOUN
fnp-3528	597	10	-	-	PUNCT
fnp-3528	597	11	binding	bind	VERB
fnp-3528	597	12	transporter	transporter	NOUN
fnp-3528	597	13	gene	gene	NOUN
fnp-3528	597	14	(	(	PUNCT
fnp-3528	597	15	abcr	abcr	NOUN
fnp-3528	597	16	)	)	PUNCT
fnp-3528	597	17	is	be	AUX
fnp-3528	597	18	mutated	mutate	VERB
fnp-3528	597	19	in	in	ADP
fnp-3528	597	20	recessive	recessive	ADJ
fnp-3528	597	21	stargardt	stargardt	ADJ
fnp-3528	597	22	macular	macular	ADJ
fnp-3528	597	23	dystrophy	dystrophy	NOUN
fnp-3528	597	24	.	.	PUNCT
fnp-3528	598	1	nat	nat	PROPN
fnp-3528	598	2	genet	genet	PROPN
fnp-3528	598	3	1997	1997	NUM
fnp-3528	598	4	,	,	PUNCT
fnp-3528	598	5	17	17	NUM
fnp-3528	598	6	,	,	PUNCT
fnp-3528	598	7	122	122	NUM
fnp-3528	598	8	.	.	PUNCT
fnp-3528	599	1	kjeldsen	kjeldsen	PROPN
fnp-3528	599	2	,	,	PUNCT
fnp-3528	599	3	e.	e.	PROPN
fnp-3528	599	4	w.	w.	PROPN
fnp-3528	599	5	;	;	PUNCT
fnp-3528	599	6	tybjaerg	tybjaerg	PROPN
fnp-3528	599	7	-	-	PUNCT
fnp-3528	599	8	hansen	hansen	PROPN
fnp-3528	599	9	,	,	PUNCT
fnp-3528	599	10	a.	a.	NOUN
fnp-3528	599	11	;	;	PUNCT
fnp-3528	599	12	nordestgaard	nordestgaard	PROPN
fnp-3528	599	13	,	,	PUNCT
fnp-3528	599	14	b.	b.	PROPN
fnp-3528	599	15	g.	g.	PROPN
fnp-3528	599	16	;	;	PUNCT
fnp-3528	599	17	frikke	frikke	NOUN
fnp-3528	599	18	-	-	PUNCT
fnp-3528	599	19	schmidt	schmidt	NOUN
fnp-3528	599	20	,	,	PUNCT
fnp-3528	599	21	r.	r.	PROPN
fnp-3528	599	22	abca7	abca7	PROPN
fnp-3528	599	23	and	and	CCONJ
fnp-3528	599	24	risk	risk	NOUN
fnp-3528	599	25	of	of	ADP
fnp-3528	599	26	dementia	dementia	NOUN
fnp-3528	599	27	and	and	CCONJ
fnp-3528	599	28	vascular	vascular	ADJ
fnp-3528	599	29	disease	disease	NOUN
fnp-3528	599	30	in	in	ADP
fnp-3528	599	31	the	the	DET
fnp-3528	599	32	danish	danish	ADJ
fnp-3528	599	33	population	population	NOUN
fnp-3528	599	34	.	.	PUNCT
fnp-3528	600	1	ann	ann	PROPN
fnp-3528	600	2	clin	clin	PROPN
fnp-3528	600	3	transl	transl	PROPN
fnp-3528	600	4	neurol	neurol	PROPN
fnp-3528	600	5	2018	2018	NUM
fnp-3528	600	6	,	,	PUNCT
fnp-3528	600	7	5	5	NUM
fnp-3528	600	8	,	,	PUNCT
fnp-3528	600	9	41	41	NUM
fnp-3528	600	10	-	-	SYM
fnp-3528	600	11	51	51	NUM
fnp-3528	600	12	.	.	PUNCT
fnp-3528	601	1	rajkumar	rajkumar	PROPN
fnp-3528	601	2	,	,	PUNCT
fnp-3528	601	3	a.	a.	NOUN
fnp-3528	601	4	p.	p.	NOUN
fnp-3528	601	5	;	;	PUNCT
fnp-3528	601	6	bidkhori	bidkhori	X
fnp-3528	601	7	,	,	PUNCT
fnp-3528	601	8	g.	g.	NOUN
fnp-3528	601	9	;	;	PUNCT
fnp-3528	601	10	shoaie	shoaie	NOUN
fnp-3528	601	11	,	,	PUNCT
fnp-3528	601	12	s.	s.	PROPN
fnp-3528	601	13	;	;	PUNCT
fnp-3528	601	14	clarke	clarke	PROPN
fnp-3528	601	15	,	,	PUNCT
fnp-3528	601	16	e.	e.	PROPN
fnp-3528	601	17	;	;	PUNCT
fnp-3528	601	18	morrin	morrin	PROPN
fnp-3528	601	19	,	,	PUNCT
fnp-3528	601	20	h.	h.	PROPN
fnp-3528	601	21	;	;	PUNCT
fnp-3528	601	22	hye	hye	PROPN
fnp-3528	601	23	,	,	PUNCT
fnp-3528	601	24	a.	a.	PROPN
fnp-3528	601	25	;	;	PUNCT
fnp-3528	601	26	williams	williams	PROPN
fnp-3528	601	27	,	,	PUNCT
fnp-3528	601	28	g.	g.	PROPN
fnp-3528	601	29	;	;	PUNCT
fnp-3528	601	30	ballard	ballard	PROPN
fnp-3528	601	31	,	,	PUNCT
fnp-3528	601	32	c.	c.	PROPN
fnp-3528	601	33	;	;	PUNCT
fnp-3528	601	34	francis	francis	PROPN
fnp-3528	601	35	,	,	PUNCT
fnp-3528	601	36	p.	p.	PROPN
fnp-3528	601	37	;	;	PUNCT
fnp-3528	601	38	aarsland	aarsland	PROPN
fnp-3528	601	39	,	,	PUNCT
fnp-3528	601	40	d.	d.	PROPN
fnp-3528	601	41	postmortem	postmortem	PROPN
fnp-3528	601	42	cortical	cortical	ADJ
fnp-3528	601	43	transcriptomics	transcriptomic	NOUN
fnp-3528	601	44	of	of	ADP
fnp-3528	601	45	lewy	lewy	PROPN
fnp-3528	601	46	body	body	NOUN
fnp-3528	601	47	dementia	dementia	NOUN
fnp-3528	601	48	reveal	reveal	VERB
fnp-3528	601	49	mitochondrial	mitochondrial	ADJ
fnp-3528	601	50	dysfunction	dysfunction	NOUN
fnp-3528	601	51	and	and	CCONJ
fnp-3528	601	52	lack	lack	NOUN
fnp-3528	601	53	of	of	ADP
fnp-3528	601	54	neuroinflammation	neuroinflammation	NOUN
fnp-3528	601	55	.	.	PUNCT
fnp-3528	602	1	am	be	AUX
fnp-3528	602	2	j	j	PROPN
fnp-3528	602	3	geriatr	geriatr	ADJ
fnp-3528	602	4	psychiatry	psychiatry	NOUN
fnp-3528	602	5	2020	2020	NUM
fnp-3528	602	6	,	,	PUNCT
fnp-3528	602	7	28	28	NUM
fnp-3528	602	8	,	,	PUNCT
fnp-3528	602	9	75	75	NUM
fnp-3528	602	10	-	-	SYM
fnp-3528	602	11	86	86	NUM
fnp-3528	602	12	.	.	PUNCT
fnp-3528	603	1	qian	qian	PROPN
fnp-3528	603	2	,	,	PUNCT
fnp-3528	603	3	l.	l.	PROPN
fnp-3528	603	4	;	;	PUNCT
fnp-3528	603	5	qin	qin	PROPN
fnp-3528	603	6	,	,	PUNCT
fnp-3528	603	7	y.	y.	PROPN
fnp-3528	603	8	;	;	PUNCT
fnp-3528	603	9	chen	chen	PROPN
fnp-3528	603	10	,	,	PUNCT
fnp-3528	603	11	x.	x.	PROPN
fnp-3528	603	12	;	;	PUNCT
fnp-3528	603	13	zhang	zhang	PROPN
fnp-3528	603	14	,	,	PUNCT
fnp-3528	603	15	f.	f.	PROPN
fnp-3528	603	16	;	;	PUNCT
fnp-3528	603	17	yang	yang	PROPN
fnp-3528	603	18	,	,	PUNCT
fnp-3528	603	19	b.	b.	PROPN
fnp-3528	603	20	;	;	PUNCT
fnp-3528	603	21	dong	dong	PROPN
fnp-3528	603	22	,	,	PUNCT
fnp-3528	603	23	k.	k.	PROPN
fnp-3528	603	24	;	;	PUNCT
fnp-3528	603	25	wang	wang	PROPN
fnp-3528	603	26	,	,	PUNCT
fnp-3528	603	27	z.	z.	PROPN
fnp-3528	603	28	;	;	PUNCT
fnp-3528	603	29	zhang	zhang	PROPN
fnp-3528	603	30	,	,	PUNCT
fnp-3528	603	31	k.	k.	PROPN
fnp-3528	603	32	atp	atp	PROPN
fnp-3528	603	33	-	-	PUNCT
fnp-3528	603	34	binding	bind	VERB
fnp-3528	603	35	cassette	cassette	NOUN
fnp-3528	603	36	transporter	transporter	NOUN
fnp-3528	603	37	13	13	NUM
fnp-3528	603	38	mrna	mrna	NOUN
fnp-3528	603	39	expression	expression	NOUN
fnp-3528	603	40	level	level	NOUN
fnp-3528	603	41	in	in	ADP
fnp-3528	603	42	schizophrenia	schizophrenia	NOUN
fnp-3528	603	43	patients	patient	NOUN
fnp-3528	603	44	.	.	PUNCT
fnp-3528	604	1	sci	sci	PROPN
fnp-3528	604	2	rep	rep	PROPN
fnp-3528	604	3	2020	2020	NUM
fnp-3528	604	4	,	,	PUNCT
fnp-3528	604	5	10	10	NUM
fnp-3528	604	6	,	,	PUNCT
fnp-3528	604	7	21498	21498	NUM
fnp-3528	604	8	.	.	PUNCT
fnp-3528	604	9	crespo	crespo	NOUN
fnp-3528	604	10	-	-	PUNCT
fnp-3528	604	11	facorro	facorro	PROPN
fnp-3528	604	12	,	,	PUNCT
fnp-3528	604	13	b.	b.	PROPN
fnp-3528	604	14	;	;	PUNCT
fnp-3528	604	15	prieto	prieto	PROPN
fnp-3528	604	16	,	,	PUNCT
fnp-3528	604	17	c.	c.	PROPN
fnp-3528	604	18	;	;	PUNCT
fnp-3528	604	19	sainz	sainz	PROPN
fnp-3528	604	20	,	,	PUNCT
fnp-3528	604	21	j.	j.	PROPN
fnp-3528	604	22	schizophrenia	schizophrenia	PROPN
fnp-3528	604	23	gene	gene	NOUN
fnp-3528	604	24	expression	expression	NOUN
fnp-3528	604	25	profile	profile	NOUN
fnp-3528	604	26	reverted	revert	VERB
fnp-3528	604	27	to	to	ADP
fnp-3528	604	28	normal	normal	ADJ
fnp-3528	604	29	levels	level	NOUN
fnp-3528	604	30	by	by	ADP
fnp-3528	604	31	antipsychotics	antipsychotic	NOUN
fnp-3528	604	32	.	.	PUNCT
fnp-3528	605	1	int	int	PROPN
fnp-3528	605	2	j	j	PROPN
fnp-3528	605	3	neuropsychopharmacol	neuropsychopharmacol	PROPN
fnp-3528	605	4	2014	2014	NUM
fnp-3528	605	5	,	,	PUNCT
fnp-3528	605	6	18	18	NUM
fnp-3528	605	7	,	,	PUNCT
fnp-3528	605	8	pyu066	pyu066	PROPN
fnp-3528	605	9	.	.	PROPN
fnp-3528	605	10	dongsheng	dongsheng	PROPN
fnp-3528	605	11	,	,	PUNCT
fnp-3528	605	12	h.	h.	PROPN
fnp-3528	605	13	;	;	PUNCT
fnp-3528	605	14	zhuo	zhuo	PROPN
fnp-3528	605	15	,	,	PUNCT
fnp-3528	605	16	z.	z.	PROPN
fnp-3528	605	17	;	;	PUNCT
fnp-3528	605	18	jiamin	jiamin	PROPN
fnp-3528	605	19	,	,	PUNCT
fnp-3528	605	20	l.	l.	PROPN
fnp-3528	605	21	;	;	PUNCT
fnp-3528	605	22	hailan	hailan	NOUN
fnp-3528	605	23	,	,	PUNCT
fnp-3528	605	24	m.	m.	NOUN
fnp-3528	605	25	;	;	PUNCT
fnp-3528	605	26	lijuan	lijuan	PROPN
fnp-3528	605	27	,	,	PUNCT
fnp-3528	605	28	h.	h.	PROPN
fnp-3528	605	29	;	;	PUNCT
fnp-3528	605	30	fan	fan	PROPN
fnp-3528	605	31	,	,	PUNCT
fnp-3528	605	32	c.	c.	PROPN
fnp-3528	605	33	;	;	PUNCT
fnp-3528	605	34	dan	dan	PROPN
fnp-3528	605	35	,	,	PUNCT
fnp-3528	605	36	y.	y.	PROPN
fnp-3528	605	37	;	;	PUNCT
fnp-3528	605	38	he	he	PRON
fnp-3528	605	39	,	,	PUNCT
fnp-3528	605	40	z.	z.	PROPN
fnp-3528	605	41	;	;	PUNCT
fnp-3528	605	42	yun	yun	PROPN
fnp-3528	605	43	,	,	PUNCT
fnp-3528	605	44	x.	x.	NOUN
fnp-3528	605	45	proteomic	proteomic	ADJ
fnp-3528	605	46	analysis	analysis	NOUN
fnp-3528	605	47	of	of	ADP
fnp-3528	605	48	the	the	DET
fnp-3528	605	49	peri	peri	NOUN
fnp-3528	605	50	-	-	PUNCT
fnp-3528	605	51	infarct	infarct	NOUN
fnp-3528	605	52	area	area	NOUN
fnp-3528	605	53	after	after	ADP
fnp-3528	605	54	human	human	ADJ
fnp-3528	605	55	umbilical	umbilical	ADJ
fnp-3528	605	56	cord	cord	NOUN
fnp-3528	605	57	mesenchymal	mesenchymal	NOUN
fnp-3528	605	58	stem	stem	NOUN
fnp-3528	605	59	cell	cell	NOUN
fnp-3528	605	60	transplantation	transplantation	NOUN
fnp-3528	605	61	in	in	ADP
fnp-3528	605	62	experimental	experimental	ADJ
fnp-3528	605	63	stroke	stroke	NOUN
fnp-3528	605	64	.	.	PUNCT
fnp-3528	606	1	aging	age	VERB
fnp-3528	606	2	dis	dis	PROPN
fnp-3528	606	3	2016	2016	NUM
fnp-3528	606	4	,	,	PUNCT
fnp-3528	606	5	7	7	NUM
fnp-3528	606	6	,	,	PUNCT
fnp-3528	606	7	623	623	NUM
fnp-3528	606	8	-	-	SYM
fnp-3528	606	9	34	34	NUM
fnp-3528	606	10	.	.	PUNCT
fnp-3528	606	11	ginguene	ginguene	PROPN
fnp-3528	606	12	,	,	PUNCT
fnp-3528	606	13	c.	c.	NOUN
fnp-3528	606	14	;	;	PUNCT
fnp-3528	606	15	champier	champier	X
fnp-3528	606	16	,	,	PUNCT
fnp-3528	606	17	j.	j.	PROPN
fnp-3528	606	18	;	;	PUNCT
fnp-3528	606	19	maallem	maallem	PROPN
fnp-3528	606	20	,	,	PUNCT
fnp-3528	606	21	s.	s.	PROPN
fnp-3528	606	22	;	;	PUNCT
fnp-3528	606	23	strazielle	strazielle	PROPN
fnp-3528	606	24	,	,	PUNCT
fnp-3528	606	25	n.	n.	NOUN
fnp-3528	606	26	;	;	PUNCT
fnp-3528	606	27	jouvet	jouvet	NOUN
fnp-3528	606	28	,	,	PUNCT
fnp-3528	606	29	a.	a.	NOUN
fnp-3528	606	30	;	;	PUNCT
fnp-3528	606	31	fevre	fevre	NOUN
fnp-3528	606	32	-	-	PUNCT
fnp-3528	606	33	montange	montange	NOUN
fnp-3528	606	34	,	,	PUNCT
fnp-3528	606	35	m.	m.	NOUN
fnp-3528	606	36	;	;	PUNCT
fnp-3528	606	37	ghersi	ghersi	NOUN
fnp-3528	606	38	-	-	PUNCT
fnp-3528	606	39	egea	egea	NOUN
fnp-3528	606	40	,	,	PUNCT
fnp-3528	607	1	j.	j.	PROPN
fnp-3528	607	2	f.	f.	PROPN
fnp-3528	607	3	p	p	PROPN
fnp-3528	607	4	-	-	PUNCT
fnp-3528	607	5	glycoprotein	glycoprotein	NOUN
fnp-3528	607	6	(	(	PUNCT
fnp-3528	607	7	abcb1	abcb1	NOUN
fnp-3528	607	8	)	)	PUNCT
fnp-3528	607	9	and	and	CCONJ
fnp-3528	607	10	breast	breast	NOUN
fnp-3528	607	11	cancer	cancer	NOUN
fnp-3528	607	12	resistance	resistance	NOUN
fnp-3528	607	13	protein	protein	NOUN
fnp-3528	607	14	(	(	PUNCT
fnp-3528	607	15	abcg2	abcg2	NOUN
fnp-3528	607	16	)	)	PUNCT
fnp-3528	607	17	localize	localize	NOUN
fnp-3528	607	18	in	in	ADP
fnp-3528	607	19	the	the	DET
fnp-3528	607	20	microvessels	microvessel	NOUN
fnp-3528	607	21	forming	form	VERB
fnp-3528	607	22	the	the	DET
fnp-3528	607	23	blood	blood	NOUN
fnp-3528	607	24	-	-	PUNCT
fnp-3528	607	25	tumor	tumor	NOUN
fnp-3528	607	26	barrier	barrier	NOUN
fnp-3528	607	27	in	in	ADP
fnp-3528	607	28	ependymomas	ependymomas	PROPN
fnp-3528	607	29	.	.	PUNCT
fnp-3528	608	1	brain	brain	NOUN
fnp-3528	608	2	pathol	pathol	NOUN
fnp-3528	608	3	2010	2010	NUM
fnp-3528	608	4	,	,	PUNCT
fnp-3528	608	5	20	20	NUM
fnp-3528	608	6	,	,	PUNCT
fnp-3528	608	7	926	926	NUM
fnp-3528	608	8	-	-	SYM
fnp-3528	608	9	35	35	NUM
fnp-3528	608	10	.	.	PUNCT
fnp-3528	609	1	bernstein	bernstein	PROPN
fnp-3528	609	2	,	,	PUNCT
fnp-3528	609	3	h.	h.	PROPN
fnp-3528	609	4	g.	g.	PROPN
fnp-3528	609	5	;	;	PUNCT
fnp-3528	609	6	hildebrandt	hildebrandt	PROPN
fnp-3528	609	7	,	,	PUNCT
fnp-3528	609	8	j.	j.	PROPN
fnp-3528	609	9	;	;	PUNCT
fnp-3528	609	10	dobrowolny	dobrowolny	PROPN
fnp-3528	609	11	,	,	PUNCT
fnp-3528	609	12	h.	h.	PROPN
fnp-3528	609	13	;	;	PUNCT
fnp-3528	609	14	steiner	steiner	PROPN
fnp-3528	609	15	,	,	PUNCT
fnp-3528	609	16	j.	j.	PROPN
fnp-3528	609	17	;	;	PUNCT
fnp-3528	609	18	bogerts	bogert	NOUN
fnp-3528	609	19	,	,	PUNCT
fnp-3528	609	20	b.	b.	PROPN
fnp-3528	609	21	;	;	PUNCT
fnp-3528	609	22	pahnke	pahnke	PROPN
fnp-3528	609	23	,	,	PUNCT
fnp-3528	609	24	j.	j.	PROPN
fnp-3528	609	25	morphometric	morphometric	PROPN
fnp-3528	609	26	analysis	analysis	NOUN
fnp-3528	609	27	of	of	ADP
fnp-3528	609	28	the	the	DET
fnp-3528	609	29	cerebral	cerebral	ADJ
fnp-3528	609	30	expression	expression	NOUN
fnp-3528	609	31	of	of	ADP
fnp-3528	609	32	atp	atp	NOUN
fnp-3528	609	33	-	-	PUNCT
fnp-3528	609	34	binding	bind	VERB
fnp-3528	609	35	cassette	cassette	NOUN
fnp-3528	609	36	transporter	transporter	NOUN
fnp-3528	609	37	protein	protein	NOUN
fnp-3528	609	38	abcb1	abcb1	NOUN
fnp-3528	609	39	in	in	ADP
fnp-3528	609	40	chronic	chronic	ADJ
fnp-3528	609	41	schizophrenia	schizophrenia	NOUN
fnp-3528	609	42	:	:	PUNCT
fnp-3528	609	43	circumscribed	circumscribed	ADJ
fnp-3528	609	44	deficits	deficit	NOUN
fnp-3528	609	45	in	in	ADP
fnp-3528	609	46	the	the	DET
fnp-3528	609	47	habenula	habenula	NOUN
fnp-3528	609	48	.	.	PUNCT
fnp-3528	610	1	schizophr	schizophr	PROPN
fnp-3528	610	2	res	re	NOUN
fnp-3528	610	3	2016	2016	NUM
fnp-3528	610	4	,	,	PUNCT
fnp-3528	610	5	177	177	NUM
fnp-3528	610	6	,	,	PUNCT
fnp-3528	610	7	52	52	NUM
fnp-3528	610	8	-	-	SYM
fnp-3528	610	9	58	58	NUM
fnp-3528	610	10	.	.	PUNCT
fnp-3528	611	1	de	de	X
fnp-3528	611	2	klerk	klerk	NOUN
fnp-3528	611	3	,	,	PUNCT
fnp-3528	611	4	o.	o.	PROPN
fnp-3528	611	5	l.	l.	PROPN
fnp-3528	611	6	;	;	PUNCT
fnp-3528	611	7	willemsen	willemsen	NOUN
fnp-3528	611	8	,	,	PUNCT
fnp-3528	611	9	a.	a.	NOUN
fnp-3528	611	10	t.	t.	PROPN
fnp-3528	611	11	;	;	PUNCT
fnp-3528	611	12	roosink	roosink	NOUN
fnp-3528	611	13	,	,	PUNCT
fnp-3528	611	14	m.	m.	NOUN
fnp-3528	611	15	;	;	PUNCT
fnp-3528	611	16	bartels	bartel	NOUN
fnp-3528	611	17	,	,	PUNCT
fnp-3528	611	18	a.	a.	PROPN
fnp-3528	611	19	l.	l.	PROPN
fnp-3528	611	20	;	;	PUNCT
fnp-3528	611	21	hendrikse	hendrikse	NOUN
fnp-3528	611	22	,	,	PUNCT
fnp-3528	611	23	n.	n.	PROPN
fnp-3528	611	24	h.	h.	PROPN
fnp-3528	611	25	;	;	PUNCT
fnp-3528	611	26	bosker	bosker	PROPN
fnp-3528	611	27	,	,	PUNCT
fnp-3528	611	28	f.	f.	PROPN
fnp-3528	611	29	j.	j.	PROPN
fnp-3528	611	30	;	;	PUNCT
fnp-3528	611	31	den	den	PROPN
fnp-3528	611	32	boer	boer	PROPN
fnp-3528	611	33	,	,	PUNCT
fnp-3528	611	34	j.	j.	PROPN
fnp-3528	611	35	a.	a.	PROPN
fnp-3528	611	36	locally	locally	ADV
fnp-3528	611	37	increased	increase	VERB
fnp-3528	611	38	p	p	ADJ
fnp-3528	611	39	-	-	PUNCT
fnp-3528	611	40	glycoprotein	glycoprotein	NOUN
fnp-3528	611	41	function	function	NOUN
fnp-3528	611	42	in	in	ADP
fnp-3528	611	43	major	major	ADJ
fnp-3528	611	44	depression	depression	NOUN
fnp-3528	611	45	:	:	PUNCT
fnp-3528	611	46	a	a	DET
fnp-3528	611	47	pet	pet	ADJ
fnp-3528	611	48	study	study	NOUN
fnp-3528	611	49	with	with	ADP
fnp-3528	611	50	[	[	X
fnp-3528	611	51	11c]verapamil	11c]verapamil	NOUN
fnp-3528	611	52	as	as	ADP
fnp-3528	611	53	a	a	DET
fnp-3528	611	54	probe	probe	NOUN
fnp-3528	611	55	for	for	ADP
fnp-3528	611	56	p	p	NOUN
fnp-3528	611	57	-	-	PUNCT
fnp-3528	611	58	glycoprotein	glycoprotein	NOUN
fnp-3528	611	59	function	function	NOUN
fnp-3528	611	60	in	in	ADP
fnp-3528	611	61	the	the	DET
fnp-3528	611	62	blood	blood	NOUN
fnp-3528	611	63	-	-	PUNCT
fnp-3528	611	64	brain	brain	NOUN
fnp-3528	611	65	barrier	barrier	NOUN
fnp-3528	611	66	.	.	PUNCT
fnp-3528	612	1	int	int	PROPN
fnp-3528	612	2	j	j	PROPN
fnp-3528	612	3	neuropsychopharmacol	neuropsychopharmacol	PROPN
fnp-3528	612	4	2009	2009	NUM
fnp-3528	612	5	,	,	PUNCT
fnp-3528	612	6	12	12	NUM
fnp-3528	612	7	,	,	PUNCT
fnp-3528	612	8	895	895	NUM
fnp-3528	612	9	-	-	SYM
fnp-3528	612	10	904	904	NUM
fnp-3528	612	11	.	.	PUNCT
fnp-3528	613	1	seegers	seeger	NOUN
fnp-3528	613	2	,	,	PUNCT
fnp-3528	613	3	u.	u.	PROPN
fnp-3528	613	4	;	;	PUNCT
fnp-3528	613	5	potschka	potschka	PROPN
fnp-3528	613	6	,	,	PUNCT
fnp-3528	613	7	h.	h.	PROPN
fnp-3528	613	8	;	;	PUNCT
fnp-3528	613	9	loscher	loscher	PROPN
fnp-3528	613	10	,	,	PUNCT
fnp-3528	613	11	w.	w.	PROPN
fnp-3528	613	12	transient	transient	PROPN
fnp-3528	613	13	increase	increase	NOUN
fnp-3528	613	14	of	of	ADP
fnp-3528	613	15	p	p	NOUN
fnp-3528	613	16	-	-	PUNCT
fnp-3528	613	17	glycoprotein	glycoprotein	NOUN
fnp-3528	613	18	expression	expression	NOUN
fnp-3528	613	19	in	in	ADP
fnp-3528	613	20	endothelium	endothelium	NOUN
fnp-3528	613	21	and	and	CCONJ
fnp-3528	613	22	parenchyma	parenchyma	NOUN
fnp-3528	613	23	of	of	ADP
fnp-3528	613	24	limbic	limbic	ADJ
fnp-3528	613	25	brain	brain	NOUN
fnp-3528	613	26	regions	region	NOUN
fnp-3528	613	27	in	in	ADP
fnp-3528	613	28	the	the	DET
fnp-3528	613	29	kainate	kainate	NOUN
fnp-3528	613	30	model	model	NOUN
fnp-3528	613	31	of	of	ADP
fnp-3528	613	32	temporal	temporal	ADJ
fnp-3528	613	33	lobe	lobe	ADJ
fnp-3528	613	34	epilepsy	epilepsy	NOUN
fnp-3528	613	35	.	.	PUNCT
fnp-3528	614	1	epilepsy	epilepsy	PROPN
fnp-3528	614	2	res	re	NOUN
fnp-3528	614	3	2002	2002	NUM
fnp-3528	614	4	,	,	PUNCT
fnp-3528	614	5	51	51	NUM
fnp-3528	614	6	,	,	PUNCT
fnp-3528	614	7	257	257	NUM
fnp-3528	614	8	-	-	SYM
fnp-3528	614	9	68	68	NUM
fnp-3528	614	10	.	.	PUNCT
fnp-3528	614	11	patak	patak	PROPN
fnp-3528	614	12	,	,	PUNCT
fnp-3528	614	13	p.	p.	PROPN
fnp-3528	614	14	;	;	PUNCT
fnp-3528	614	15	hermann	hermann	PROPN
fnp-3528	614	16	,	,	PUNCT
fnp-3528	614	17	d.	d.	PROPN
fnp-3528	614	18	m.	m.	PROPN
fnp-3528	614	19	atp	atp	PROPN
fnp-3528	614	20	-	-	PUNCT
fnp-3528	614	21	binding	bind	VERB
fnp-3528	614	22	cassette	cassette	NOUN
fnp-3528	614	23	transporters	transporter	NOUN
fnp-3528	614	24	at	at	ADP
fnp-3528	614	25	the	the	DET
fnp-3528	614	26	blood	blood	NOUN
fnp-3528	614	27	-	-	PUNCT
fnp-3528	614	28	brain	brain	NOUN
fnp-3528	614	29	barrier	barrier	NOUN
fnp-3528	614	30	in	in	ADP
fnp-3528	614	31	ischaemic	ischaemic	ADJ
fnp-3528	614	32	stroke	stroke	NOUN
fnp-3528	614	33	.	.	PUNCT
fnp-3528	615	1	curr	curr	PROPN
fnp-3528	615	2	pharm	pharm	PROPN
fnp-3528	615	3	des	des	PROPN
fnp-3528	615	4	2011	2011	NUM
fnp-3528	615	5	,	,	PUNCT
fnp-3528	615	6	17	17	NUM
fnp-3528	615	7	,	,	PUNCT
fnp-3528	615	8	2787	2787	NUM
fnp-3528	615	9	-	-	SYM
fnp-3528	615	10	92	92	NUM
fnp-3528	615	11	.	.	PUNCT
fnp-3528	616	1	bartels	bartel	NOUN
fnp-3528	616	2	,	,	PUNCT
fnp-3528	616	3	a.	a.	PROPN
fnp-3528	616	4	l.	l.	PROPN
fnp-3528	616	5	;	;	PUNCT
fnp-3528	616	6	willemsen	willemsen	NOUN
fnp-3528	616	7	,	,	PUNCT
fnp-3528	616	8	a.	a.	NOUN
fnp-3528	616	9	t.	t.	PROPN
fnp-3528	616	10	;	;	PUNCT
fnp-3528	616	11	kortekaas	kortekaas	PROPN
fnp-3528	616	12	,	,	PUNCT
fnp-3528	616	13	r.	r.	PROPN
fnp-3528	616	14	;	;	PUNCT
fnp-3528	616	15	de	de	PROPN
fnp-3528	616	16	jong	jong	PROPN
fnp-3528	616	17	,	,	PUNCT
fnp-3528	616	18	b.	b.	PROPN
fnp-3528	616	19	m.	m.	PROPN
fnp-3528	616	20	;	;	PUNCT
fnp-3528	616	21	de	de	PROPN
fnp-3528	616	22	vries	vries	PROPN
fnp-3528	616	23	,	,	PUNCT
fnp-3528	616	24	r.	r.	PROPN
fnp-3528	616	25	;	;	PUNCT
fnp-3528	616	26	de	de	X
fnp-3528	616	27	klerk	klerk	NOUN
fnp-3528	616	28	,	,	PUNCT
fnp-3528	616	29	o.	o.	PROPN
fnp-3528	616	30	;	;	PUNCT
fnp-3528	616	31	van	van	PROPN
fnp-3528	616	32	oostrom	oostrom	PROPN
fnp-3528	616	33	,	,	PUNCT
fnp-3528	616	34	j.	j.	PROPN
fnp-3528	616	35	c.	c.	PROPN
fnp-3528	616	36	;	;	PUNCT
fnp-3528	616	37	portman	portman	PROPN
fnp-3528	616	38	,	,	PUNCT
fnp-3528	616	39	a.	a.	NOUN
fnp-3528	616	40	;	;	PUNCT
fnp-3528	616	41	leenders	leenders	PROPN
fnp-3528	616	42	,	,	PUNCT
fnp-3528	616	43	k.	k.	PROPN
fnp-3528	616	44	l.	l.	PROPN
fnp-3528	616	45	decreased	decrease	VERB
fnp-3528	616	46	blood	blood	NOUN
fnp-3528	616	47	-	-	PUNCT
fnp-3528	616	48	brain	brain	NOUN
fnp-3528	616	49	barrier	barrier	NOUN
fnp-3528	616	50	p	p	NOUN
fnp-3528	616	51	-	-	PUNCT
fnp-3528	616	52	glycoprotein	glycoprotein	NOUN
fnp-3528	616	53	function	function	NOUN
fnp-3528	616	54	in	in	ADP
fnp-3528	616	55	the	the	DET
fnp-3528	616	56	progression	progression	NOUN
fnp-3528	616	57	of	of	ADP
fnp-3528	616	58	parkinson	parkinson	NOUN
fnp-3528	616	59	's	's	PART
fnp-3528	616	60	disease	disease	NOUN
fnp-3528	616	61	,	,	PUNCT
fnp-3528	616	62	psp	psp	NOUN
fnp-3528	616	63	and	and	CCONJ
fnp-3528	616	64	msa	msa	PROPN
fnp-3528	616	65	.	.	PROPN
fnp-3528	617	1	j	j	PROPN
fnp-3528	617	2	neural	neural	ADJ
fnp-3528	617	3	transm	transm	PROPN
fnp-3528	617	4	(	(	PUNCT
fnp-3528	617	5	vienna	vienna	PROPN
fnp-3528	617	6	)	)	PUNCT
fnp-3528	617	7	2008	2008	NUM
fnp-3528	617	8	,	,	PUNCT
fnp-3528	617	9	115	115	NUM
fnp-3528	617	10	,	,	PUNCT
fnp-3528	617	11	1001	1001	NUM
fnp-3528	617	12	-	-	SYM
fnp-3528	617	13	9	9	NUM
fnp-3528	617	14	.	.	PUNCT
fnp-3528	617	15	vautier	vautier	NOUN
fnp-3528	617	16	,	,	PUNCT
fnp-3528	617	17	s.	s.	PROPN
fnp-3528	617	18	;	;	PUNCT
fnp-3528	617	19	fernandez	fernandez	PROPN
fnp-3528	617	20	,	,	PUNCT
fnp-3528	617	21	c.	c.	PROPN
fnp-3528	617	22	abcb1	abcb1	PROPN
fnp-3528	617	23	:	:	PUNCT
fnp-3528	617	24	the	the	DET
fnp-3528	617	25	role	role	NOUN
fnp-3528	617	26	in	in	ADP
fnp-3528	617	27	parkinson	parkinson	NOUN
fnp-3528	617	28	's	's	PART
fnp-3528	617	29	disease	disease	NOUN
fnp-3528	617	30	and	and	CCONJ
fnp-3528	617	31	pharmacokinetics	pharmacokinetic	NOUN
fnp-3528	617	32	of	of	ADP
fnp-3528	617	33	antiparkinsonian	antiparkinsonian	ADJ
fnp-3528	617	34	drugs	drug	NOUN
fnp-3528	617	35	.	.	PUNCT
fnp-3528	618	1	expert	expert	NOUN
fnp-3528	618	2	opin	opin	NOUN
fnp-3528	618	3	drug	drug	NOUN
fnp-3528	618	4	metab	metab	NOUN
fnp-3528	618	5	toxicol	toxicol	NOUN
fnp-3528	618	6	2009	2009	NUM
fnp-3528	618	7	,	,	PUNCT
fnp-3528	618	8	5	5	NUM
fnp-3528	618	9	,	,	PUNCT
fnp-3528	618	10	1349	1349	NUM
fnp-3528	618	11	-	-	SYM
fnp-3528	618	12	58	58	NUM
fnp-3528	618	13	.	.	PUNCT
fnp-3528	619	1	bernstein	bernstein	PROPN
fnp-3528	619	2	,	,	PUNCT
fnp-3528	619	3	h.	h.	PROPN
fnp-3528	619	4	g.	g.	PROPN
fnp-3528	619	5	;	;	PUNCT
fnp-3528	619	6	holzl	holzl	NOUN
fnp-3528	619	7	,	,	PUNCT
fnp-3528	619	8	g.	g.	PROPN
fnp-3528	619	9	;	;	PUNCT
fnp-3528	619	10	dobrowolny	dobrowolny	PROPN
fnp-3528	619	11	,	,	PUNCT
fnp-3528	619	12	h.	h.	PROPN
fnp-3528	619	13	;	;	PUNCT
fnp-3528	619	14	hildebrandt	hildebrandt	PROPN
fnp-3528	619	15	,	,	PUNCT
fnp-3528	619	16	j.	j.	PROPN
fnp-3528	619	17	;	;	PUNCT
fnp-3528	619	18	trubner	trubner	PROPN
fnp-3528	619	19	,	,	PUNCT
fnp-3528	619	20	k.	k.	PROPN
fnp-3528	619	21	;	;	PUNCT
fnp-3528	619	22	krohn	krohn	PROPN
fnp-3528	619	23	,	,	PUNCT
fnp-3528	619	24	m.	m.	NOUN
fnp-3528	619	25	;	;	PUNCT
fnp-3528	619	26	bogerts	bogert	NOUN
fnp-3528	619	27	,	,	PUNCT
fnp-3528	619	28	b.	b.	PROPN
fnp-3528	619	29	;	;	PUNCT
fnp-3528	619	30	pahnke	pahnke	PROPN
fnp-3528	619	31	,	,	PUNCT
fnp-3528	619	32	j.	j.	PROPN
fnp-3528	619	33	vascular	vascular	ADJ
fnp-3528	619	34	and	and	CCONJ
fnp-3528	619	35	extravascular	extravascular	ADJ
fnp-3528	619	36	distribution	distribution	NOUN
fnp-3528	619	37	of	of	ADP
fnp-3528	619	38	the	the	DET
fnp-3528	619	39	atp	atp	NOUN
fnp-3528	619	40	-	-	PUNCT
fnp-3528	619	41	binding	bind	VERB
fnp-3528	619	42	cassette	cassette	NOUN
fnp-3528	619	43	transporters	transporter	NOUN
fnp-3528	619	44	abcb1	abcb1	NOUN
fnp-3528	619	45	and	and	CCONJ
fnp-3528	619	46	abcc1	abcc1	NOUN
fnp-3528	619	47	in	in	ADP
fnp-3528	619	48	aged	aged	ADJ
fnp-3528	619	49	human	human	ADJ
fnp-3528	619	50	brain	brain	NOUN
fnp-3528	619	51	and	and	CCONJ
fnp-3528	619	52	pituitary	pituitary	ADJ
fnp-3528	619	53	.	.	PUNCT
fnp-3528	620	1	mech	mech	NOUN
fnp-3528	620	2	ageing	age	VERB
fnp-3528	620	3	dev	dev	NOUN
fnp-3528	620	4	2014	2014	NUM
fnp-3528	620	5	,	,	PUNCT
fnp-3528	620	6	141	141	NUM
fnp-3528	620	7	-	-	SYM
fnp-3528	620	8	142	142	NUM
fnp-3528	620	9	,	,	PUNCT
fnp-3528	620	10	12	12	NUM
fnp-3528	620	11	-	-	SYM
fnp-3528	620	12	21	21	NUM
fnp-3528	620	13	.	.	PUNCT
fnp-3528	620	14	vogelgesang	vogelgesang	PROPN
fnp-3528	620	15	,	,	PUNCT
fnp-3528	620	16	s.	s.	PROPN
fnp-3528	620	17	;	;	PUNCT
fnp-3528	620	18	glatzel	glatzel	NOUN
fnp-3528	620	19	,	,	PUNCT
fnp-3528	620	20	m.	m.	NOUN
fnp-3528	620	21	;	;	PUNCT
fnp-3528	620	22	walker	walker	PROPN
fnp-3528	620	23	,	,	PUNCT
fnp-3528	620	24	l.	l.	PROPN
fnp-3528	620	25	c.	c.	PROPN
fnp-3528	620	26	;	;	PUNCT
fnp-3528	620	27	kroemer	kroemer	PROPN
fnp-3528	620	28	,	,	PUNCT
fnp-3528	620	29	h.	h.	PROPN
fnp-3528	620	30	k.	k.	PROPN
fnp-3528	620	31	;	;	PUNCT
fnp-3528	620	32	aguzzi	aguzzi	NOUN
fnp-3528	620	33	,	,	PUNCT
fnp-3528	620	34	a.	a.	NOUN
fnp-3528	620	35	;	;	PUNCT
fnp-3528	620	36	warzok	warzok	PROPN
fnp-3528	620	37	,	,	PUNCT
fnp-3528	620	38	r.	r.	PROPN
fnp-3528	620	39	w.	w.	PROPN
fnp-3528	620	40	cerebrovascular	cerebrovascular	PROPN
fnp-3528	620	41	p	p	ADJ
fnp-3528	620	42	-	-	PUNCT
fnp-3528	620	43	glycoprotein	glycoprotein	NOUN
fnp-3528	620	44	expression	expression	NOUN
fnp-3528	620	45	is	be	AUX
fnp-3528	620	46	decreased	decrease	VERB
fnp-3528	620	47	in	in	ADP
fnp-3528	620	48	creutzfeldt	creutzfeldt	ADJ
fnp-3528	620	49	-	-	ADJ
fnp-3528	620	50	jakob	jakob	ADJ
fnp-3528	620	51	disease	disease	NOUN
fnp-3528	620	52	.	.	PUNCT
fnp-3528	621	1	acta	acta	PROPN
fnp-3528	621	2	neuropathol	neuropathol	PROPN
fnp-3528	621	3	2006	2006	NUM
fnp-3528	621	4	,	,	PUNCT
fnp-3528	621	5	111	111	NUM
fnp-3528	621	6	,	,	PUNCT
fnp-3528	621	7	436	436	NUM
fnp-3528	621	8	-	-	SYM
fnp-3528	621	9	43	43	NUM
fnp-3528	621	10	.	.	PUNCT
fnp-3528	622	1	chi	chi	PROPN
fnp-3528	622	2	,	,	PUNCT
fnp-3528	622	3	h.	h.	PROPN
fnp-3528	622	4	;	;	PUNCT
fnp-3528	622	5	tang	tang	PROPN
fnp-3528	622	6	,	,	PUNCT
fnp-3528	622	7	w.	w.	PROPN
fnp-3528	622	8	;	;	PUNCT
fnp-3528	622	9	bai	bai	PROPN
fnp-3528	622	10	,	,	PUNCT
fnp-3528	622	11	y.	y.	PROPN
fnp-3528	622	12	molecular	molecular	ADJ
fnp-3528	622	13	evidence	evidence	NOUN
fnp-3528	622	14	of	of	ADP
fnp-3528	622	15	impaired	impaired	ADJ
fnp-3528	622	16	iron	iron	NOUN
fnp-3528	622	17	metabolism	metabolism	NOUN
fnp-3528	622	18	and	and	CCONJ
fnp-3528	622	19	its	its	PRON
fnp-3528	622	20	association	association	NOUN
fnp-3528	622	21	with	with	ADP
fnp-3528	622	22	parkinson	parkinson	NOUN
fnp-3528	622	23	's	's	PART
fnp-3528	622	24	disease	disease	NOUN
fnp-3528	622	25	progression	progression	NOUN
fnp-3528	622	26	.	.	PUNCT
fnp-3528	623	1	3	3	NUM
fnp-3528	623	2	biotech	biotech	NOUN
fnp-3528	623	3	2020	2020	NUM
fnp-3528	623	4	,	,	PUNCT
fnp-3528	623	5	10	10	NUM
fnp-3528	623	6	,	,	PUNCT
fnp-3528	623	7	173	173	NUM
fnp-3528	623	8	.	.	PUNCT
fnp-3528	623	9	chuang	chuang	PROPN
fnp-3528	623	10	,	,	PUNCT
fnp-3528	623	11	y.	y.	PROPN
fnp-3528	623	12	h.	h.	PROPN
fnp-3528	623	13	;	;	PUNCT
fnp-3528	623	14	paul	paul	PROPN
fnp-3528	623	15	,	,	PUNCT
fnp-3528	623	16	k.	k.	PROPN
fnp-3528	623	17	c.	c.	PROPN
fnp-3528	623	18	;	;	PUNCT
fnp-3528	623	19	bronstein	bronstein	PROPN
fnp-3528	623	20	,	,	PUNCT
fnp-3528	623	21	j.	j.	PROPN
fnp-3528	623	22	m.	m.	PROPN
fnp-3528	623	23	;	;	PUNCT
fnp-3528	623	24	bordelon	bordelon	NOUN
fnp-3528	623	25	,	,	PUNCT
fnp-3528	623	26	y.	y.	PROPN
fnp-3528	623	27	;	;	PUNCT
fnp-3528	623	28	horvath	horvath	PROPN
fnp-3528	623	29	,	,	PUNCT
fnp-3528	623	30	s.	s.	PROPN
fnp-3528	623	31	;	;	PUNCT
fnp-3528	623	32	ritz	ritz	PROPN
fnp-3528	623	33	,	,	PUNCT
fnp-3528	623	34	b.	b.	PROPN
fnp-3528	623	35	parkinson	parkinson	PROPN
fnp-3528	623	36	's	's	PART
fnp-3528	623	37	disease	disease	NOUN
fnp-3528	623	38	is	be	AUX
fnp-3528	623	39	associated	associate	VERB
fnp-3528	623	40	with	with	ADP
fnp-3528	623	41	dna	dna	PROPN
fnp-3528	623	42	methylation	methylation	NOUN
fnp-3528	623	43	levels	level	NOUN
fnp-3528	623	44	in	in	ADP
fnp-3528	623	45	human	human	ADJ
fnp-3528	623	46	blood	blood	NOUN
fnp-3528	623	47	and	and	CCONJ
fnp-3528	623	48	saliva	saliva	NOUN
fnp-3528	623	49	.	.	PUNCT
fnp-3528	624	1	genome	genome	NOUN
fnp-3528	624	2	med	me	VERB
fnp-3528	624	3	2017	2017	NUM
fnp-3528	624	4	,	,	PUNCT
fnp-3528	624	5	9	9	NUM
fnp-3528	624	6	,	,	PUNCT
fnp-3528	624	7	76	76	NUM
fnp-3528	624	8	.	.	PUNCT
fnp-3528	625	1	decleves	decleve	NOUN
fnp-3528	625	2	,	,	PUNCT
fnp-3528	625	3	x.	x.	NOUN
fnp-3528	625	4	;	;	PUNCT
fnp-3528	625	5	fajac	fajac	PROPN
fnp-3528	625	6	,	,	PUNCT
fnp-3528	625	7	a.	a.	NOUN
fnp-3528	625	8	;	;	PUNCT
fnp-3528	625	9	lehmann	lehmann	PROPN
fnp-3528	625	10	-	-	PUNCT
fnp-3528	625	11	che	che	PROPN
fnp-3528	625	12	,	,	PUNCT
fnp-3528	625	13	j.	j.	PROPN
fnp-3528	625	14	;	;	PUNCT
fnp-3528	625	15	tardy	tardy	ADJ
fnp-3528	625	16	,	,	PUNCT
fnp-3528	625	17	m.	m.	NOUN
fnp-3528	625	18	;	;	PUNCT
fnp-3528	625	19	mercier	mercier	X
fnp-3528	625	20	,	,	PUNCT
fnp-3528	625	21	c.	c.	NOUN
fnp-3528	625	22	;	;	PUNCT
fnp-3528	625	23	hurbain	hurbain	NOUN
fnp-3528	625	24	,	,	PUNCT
fnp-3528	625	25	i.	i.	NOUN
fnp-3528	625	26	;	;	PUNCT
fnp-3528	625	27	laplanche	laplanche	PROPN
fnp-3528	625	28	,	,	PUNCT
fnp-3528	625	29	j.	j.	PROPN
fnp-3528	625	30	l.	l.	PROPN
fnp-3528	625	31	;	;	PUNCT
fnp-3528	625	32	bernaudin	bernaudin	PROPN
fnp-3528	625	33	,	,	PUNCT
fnp-3528	625	34	j.	j.	PROPN
fnp-3528	625	35	f.	f.	PROPN
fnp-3528	625	36	;	;	PUNCT
fnp-3528	625	37	scherrmann	scherrmann	PROPN
fnp-3528	625	38	,	,	PUNCT
fnp-3528	625	39	j.	j.	PROPN
fnp-3528	625	40	m.	m.	PROPN
fnp-3528	625	41	molecular	molecular	ADJ
fnp-3528	625	42	and	and	CCONJ
fnp-3528	625	43	functional	functional	ADJ
fnp-3528	625	44	mdr1	mdr1	PROPN
fnp-3528	625	45	-	-	PUNCT
fnp-3528	625	46	pgp	pgp	NOUN
fnp-3528	625	47	and	and	CCONJ
fnp-3528	625	48	mrps	mrps	NOUN
fnp-3528	625	49	expression	expression	NOUN
fnp-3528	625	50	in	in	ADP
fnp-3528	625	51	human	human	ADJ
fnp-3528	625	52	glioblastoma	glioblastoma	NOUN
fnp-3528	625	53	multiforme	multiforme	NOUN
fnp-3528	625	54	cell	cell	NOUN
fnp-3528	625	55	lines	line	NOUN
fnp-3528	625	56	.	.	PUNCT
fnp-3528	626	1	int	int	NOUN
fnp-3528	626	2	j	j	PROPN
fnp-3528	626	3	cancer	cancer	NOUN
fnp-3528	626	4	.	.	PUNCT
fnp-3528	627	1	2002	2002	NUM
fnp-3528	627	2	,	,	PUNCT
fnp-3528	627	3	98	98	NUM
fnp-3528	627	4	,	,	PUNCT
fnp-3528	627	5	173	173	NUM
fnp-3528	627	6	-	-	SYM
fnp-3528	627	7	80	80	NUM
fnp-3528	627	8	.	.	PUNCT
fnp-3528	628	1	kilic	kilic	PROPN
fnp-3528	628	2	,	,	PUNCT
fnp-3528	628	3	e.	e.	PROPN
fnp-3528	628	4	;	;	PUNCT
fnp-3528	628	5	spudich	spudich	NOUN
fnp-3528	628	6	,	,	PUNCT
fnp-3528	628	7	a.	a.	NOUN
fnp-3528	628	8	;	;	PUNCT
fnp-3528	628	9	kilic	kilic	NOUN
fnp-3528	628	10	,	,	PUNCT
fnp-3528	628	11	u.	u.	PROPN
fnp-3528	628	12	;	;	PUNCT
fnp-3528	628	13	rentsch	rentsch	PROPN
fnp-3528	628	14	,	,	PUNCT
fnp-3528	628	15	k.	k.	PROPN
fnp-3528	628	16	m.	m.	PROPN
fnp-3528	628	17	;	;	PUNCT
fnp-3528	628	18	vig	vig	PROPN
fnp-3528	628	19	,	,	PUNCT
fnp-3528	628	20	r.	r.	PROPN
fnp-3528	628	21	;	;	PUNCT
fnp-3528	628	22	matter	matter	NOUN
fnp-3528	628	23	,	,	PUNCT
fnp-3528	628	24	c.	c.	PROPN
fnp-3528	628	25	m.	m.	NOUN
fnp-3528	628	26	;	;	PUNCT
fnp-3528	628	27	wunderli	wunderli	NOUN
fnp-3528	628	28	-	-	PUNCT
fnp-3528	628	29	allenspach	allenspach	NOUN
fnp-3528	628	30	,	,	PUNCT
fnp-3528	628	31	h.	h.	PROPN
fnp-3528	628	32	;	;	PUNCT
fnp-3528	628	33	fritschy	fritschy	NOUN
fnp-3528	628	34	,	,	PUNCT
fnp-3528	628	35	j.	j.	PROPN
fnp-3528	628	36	m.	m.	PROPN
fnp-3528	628	37	;	;	PUNCT
fnp-3528	628	38	bassetti	bassetti	PROPN
fnp-3528	628	39	,	,	PUNCT
fnp-3528	628	40	c.	c.	PROPN
fnp-3528	628	41	l.	l.	PROPN
fnp-3528	628	42	;	;	PUNCT
fnp-3528	628	43	hermann	hermann	PROPN
fnp-3528	628	44	,	,	PUNCT
fnp-3528	628	45	d.	d.	PROPN
fnp-3528	628	46	m.	m.	PROPN
fnp-3528	628	47	abcc1	abcc1	PROPN
fnp-3528	628	48	:	:	PUNCT
fnp-3528	628	49	a	a	DET
fnp-3528	628	50	gateway	gateway	NOUN
fnp-3528	628	51	for	for	ADP
fnp-3528	628	52	pharmacological	pharmacological	ADJ
fnp-3528	628	53	compounds	compound	NOUN
fnp-3528	628	54	to	to	ADP
fnp-3528	628	55	the	the	DET
fnp-3528	628	56	ischaemic	ischaemic	ADJ
fnp-3528	628	57	brain	brain	NOUN
fnp-3528	628	58	.	.	PUNCT
fnp-3528	629	1	brain	brain	PROPN
fnp-3528	629	2	2008	2008	NUM
fnp-3528	629	3	,	,	PUNCT
fnp-3528	629	4	131	131	NUM
fnp-3528	629	5	,	,	PUNCT
fnp-3528	629	6	2679	2679	NUM
fnp-3528	629	7	-	-	SYM
fnp-3528	629	8	89	89	NUM
fnp-3528	629	9	.	.	PUNCT
fnp-3528	630	1	vidal	vidal	NOUN
fnp-3528	630	2	-	-	PUNCT
fnp-3528	630	3	taboada	taboada	PROPN
fnp-3528	630	4	,	,	PUNCT
fnp-3528	630	5	j.	j.	PROPN
fnp-3528	630	6	m.	m.	PROPN
fnp-3528	630	7	;	;	PUNCT
fnp-3528	630	8	pugliese	pugliese	NOUN
fnp-3528	630	9	,	,	PUNCT
fnp-3528	630	10	m.	m.	NOUN
fnp-3528	630	11	;	;	PUNCT
fnp-3528	630	12	salvado	salvado	NOUN
fnp-3528	630	13	,	,	PUNCT
fnp-3528	630	14	m.	m.	NOUN
fnp-3528	630	15	;	;	PUNCT
fnp-3528	630	16	gamez	gamez	NOUN
fnp-3528	630	17	,	,	PUNCT
fnp-3528	630	18	j.	j.	PROPN
fnp-3528	630	19	;	;	PUNCT
fnp-3528	630	20	mahy	mahy	PROPN
fnp-3528	630	21	,	,	PUNCT
fnp-3528	630	22	n.	n.	NOUN
fnp-3528	630	23	;	;	PUNCT
fnp-3528	630	24	rodriguez	rodriguez	NOUN
fnp-3528	630	25	,	,	PUNCT
fnp-3528	630	26	m.	m.	NOUN
fnp-3528	630	27	j.	j.	PROPN
fnp-3528	630	28	katp	katp	PROPN
fnp-3528	630	29	channel	channel	NOUN
fnp-3528	630	30	expression	expression	NOUN
fnp-3528	630	31	and	and	CCONJ
fnp-3528	630	32	genetic	genetic	ADJ
fnp-3528	630	33	polymorphisms	polymorphism	NOUN
fnp-3528	630	34	associated	associate	VERB
fnp-3528	630	35	with	with	ADP
fnp-3528	630	36	progression	progression	NOUN
fnp-3528	630	37	and	and	CCONJ
fnp-3528	630	38	survival	survival	NOUN
fnp-3528	630	39	in	in	ADP
fnp-3528	630	40	amyotrophic	amyotrophic	ADJ
fnp-3528	630	41	lateral	lateral	ADJ
fnp-3528	630	42	sclerosis	sclerosis	NOUN
fnp-3528	630	43	.	.	PUNCT
fnp-3528	631	1	mol	mol	ADP
fnp-3528	631	2	neurobiol	neurobiol	PROPN
fnp-3528	631	3	2018	2018	NUM
fnp-3528	631	4	,	,	PUNCT
fnp-3528	631	5	55	55	NUM
fnp-3528	631	6	,	,	PUNCT
fnp-3528	631	7	7962	7962	NUM
fnp-3528	631	8	-	-	SYM
fnp-3528	631	9	72	72	NUM
fnp-3528	631	10	.	.	PUNCT
fnp-3528	632	1	crary	crary	PROPN
fnp-3528	632	2	,	,	PUNCT
fnp-3528	632	3	j.	j.	PROPN
fnp-3528	632	4	f.	f.	PROPN
fnp-3528	632	5	top	top	PROPN
fnp-3528	632	6	ten	ten	NUM
fnp-3528	632	7	discoveries	discovery	NOUN
fnp-3528	632	8	of	of	ADP
fnp-3528	632	9	the	the	DET
fnp-3528	632	10	year	year	NOUN
fnp-3528	632	11	:	:	PUNCT
fnp-3528	632	12	neurodegeneration	neurodegeneration	NOUN
fnp-3528	632	13	.	.	PUNCT
fnp-3528	633	1	free	free	ADJ
fnp-3528	633	2	neuropathol	neuropathol	NOUN
fnp-3528	633	3	2020	2020	NUM
fnp-3528	633	4	,	,	PUNCT
fnp-3528	633	5	1	1	NUM
fnp-3528	633	6	,	,	PUNCT
fnp-3528	633	7	12	12	NUM
fnp-3528	633	8	.	.	PUNCT
fnp-3528	634	1	nelson	nelson	PROPN
fnp-3528	634	2	,	,	PUNCT
fnp-3528	634	3	p.	p.	PROPN
fnp-3528	634	4	t.	t.	PROPN
fnp-3528	634	5	;	;	PUNCT
fnp-3528	634	6	jicha	jicha	PROPN
fnp-3528	634	7	,	,	PUNCT
fnp-3528	634	8	g.	g.	PROPN
fnp-3528	634	9	a.	a.	PROPN
fnp-3528	634	10	;	;	PUNCT
fnp-3528	634	11	wang	wang	PROPN
fnp-3528	634	12	,	,	PUNCT
fnp-3528	634	13	w.	w.	PROPN
fnp-3528	634	14	x.	x.	PROPN
fnp-3528	634	15	;	;	PUNCT
fnp-3528	634	16	ighodaro	ighodaro	NOUN
fnp-3528	634	17	,	,	PUNCT
fnp-3528	634	18	e.	e.	PROPN
fnp-3528	634	19	;	;	PUNCT
fnp-3528	634	20	artiushin	artiushin	PROPN
fnp-3528	634	21	,	,	PUNCT
fnp-3528	634	22	s.	s.	PROPN
fnp-3528	634	23	;	;	PUNCT
fnp-3528	634	24	nichols	nichols	PROPN
fnp-3528	634	25	,	,	PUNCT
fnp-3528	634	26	c.	c.	PROPN
fnp-3528	634	27	g.	g.	PROPN
fnp-3528	634	28	;	;	PUNCT
fnp-3528	634	29	fardo	fardo	PROPN
fnp-3528	634	30	,	,	PUNCT
fnp-3528	634	31	d.	d.	PROPN
fnp-3528	634	32	w.	w.	PROPN
fnp-3528	634	33	abcc9	abcc9	PROPN
fnp-3528	634	34	/	/	SYM
fnp-3528	634	35	sur2	sur2	NOUN
fnp-3528	634	36	in	in	ADP
fnp-3528	634	37	the	the	DET
fnp-3528	634	38	brain	brain	NOUN
fnp-3528	634	39	:	:	PUNCT
fnp-3528	634	40	implications	implication	NOUN
fnp-3528	634	41	for	for	ADP
fnp-3528	634	42	hippocampal	hippocampal	ADJ
fnp-3528	634	43	sclerosis	sclerosis	NOUN
fnp-3528	634	44	of	of	ADP
fnp-3528	634	45	aging	aging	NOUN
fnp-3528	634	46	and	and	CCONJ
fnp-3528	634	47	a	a	DET
fnp-3528	634	48	potential	potential	ADJ
fnp-3528	634	49	therapeutic	therapeutic	ADJ
fnp-3528	634	50	target	target	NOUN
fnp-3528	634	51	.	.	PUNCT
fnp-3528	635	1	ageing	age	VERB
fnp-3528	635	2	res	re	NOUN
fnp-3528	635	3	rev	rev	X
fnp-3528	635	4	2015	2015	NUM
fnp-3528	635	5	,	,	PUNCT
fnp-3528	635	6	24	24	NUM
fnp-3528	635	7	,	,	PUNCT
fnp-3528	635	8	111	111	NUM
fnp-3528	635	9	-	-	SYM
fnp-3528	635	10	25	25	NUM
fnp-3528	635	11	.	.	PUNCT
fnp-3528	636	1	berger	berger	PROPN
fnp-3528	636	2	,	,	PUNCT
fnp-3528	636	3	j.	j.	PROPN
fnp-3528	636	4	;	;	PUNCT
fnp-3528	636	5	forss	forss	ADJ
fnp-3528	636	6	-	-	PUNCT
fnp-3528	636	7	petter	petter	NOUN
fnp-3528	636	8	,	,	PUNCT
fnp-3528	636	9	s.	s.	PROPN
fnp-3528	636	10	;	;	PUNCT
fnp-3528	636	11	eichler	eichler	NOUN
fnp-3528	636	12	,	,	PUNCT
fnp-3528	636	13	f.	f.	PROPN
fnp-3528	636	14	s.	s.	PROPN
fnp-3528	636	15	pathophysiology	pathophysiology	PROPN
fnp-3528	636	16	of	of	ADP
fnp-3528	636	17	x	x	NOUN
fnp-3528	636	18	-	-	ADJ
fnp-3528	636	19	linked	link	VERB
fnp-3528	636	20	adrenoleukodystrophy	adrenoleukodystrophy	NOUN
fnp-3528	636	21	.	.	PUNCT
fnp-3528	637	1	biochim	biochim	PROPN
fnp-3528	637	2	2014	2014	NUM
fnp-3528	637	3	,	,	PUNCT
fnp-3528	637	4	98	98	NUM
fnp-3528	637	5	,	,	PUNCT
fnp-3528	637	6	135	135	NUM
fnp-3528	637	7	-	-	SYM
fnp-3528	637	8	42	42	NUM
fnp-3528	637	9	.	.	PUNCT
fnp-3528	638	1	tansley	tansley	NOUN
fnp-3528	638	2	,	,	PUNCT
fnp-3528	638	3	g.	g.	PROPN
fnp-3528	638	4	h.	h.	PROPN
fnp-3528	638	5	;	;	PUNCT
fnp-3528	638	6	burgess	burgess	PROPN
fnp-3528	638	7	,	,	PUNCT
fnp-3528	638	8	b.	b.	PROPN
fnp-3528	638	9	l.	l.	PROPN
fnp-3528	638	10	;	;	PUNCT
fnp-3528	638	11	bryan	bryan	PROPN
fnp-3528	638	12	,	,	PUNCT
fnp-3528	638	13	m.	m.	NOUN
fnp-3528	638	14	t.	t.	PROPN
fnp-3528	638	15	;	;	PUNCT
fnp-3528	638	16	su	su	PROPN
fnp-3528	638	17	,	,	PUNCT
fnp-3528	638	18	y.	y.	PROPN
fnp-3528	638	19	;	;	PUNCT
fnp-3528	638	20	hirsch	hirsch	PROPN
fnp-3528	638	21	-	-	PUNCT
fnp-3528	638	22	reinshagen	reinshagen	NOUN
fnp-3528	638	23	,	,	PUNCT
fnp-3528	638	24	v.	v.	PROPN
fnp-3528	638	25	;	;	PUNCT
fnp-3528	638	26	pearce	pearce	PROPN
fnp-3528	638	27	,	,	PUNCT
fnp-3528	638	28	j.	j.	PROPN
fnp-3528	638	29	;	;	PUNCT
fnp-3528	638	30	chan	chan	PROPN
fnp-3528	638	31	,	,	PUNCT
fnp-3528	638	32	j.	j.	PROPN
fnp-3528	638	33	y.	y.	PROPN
fnp-3528	638	34	;	;	PUNCT
fnp-3528	638	35	wilkinson	wilkinson	PROPN
fnp-3528	638	36	,	,	PUNCT
fnp-3528	638	37	a.	a.	PROPN
fnp-3528	638	38	;	;	PUNCT
fnp-3528	638	39	evans	evans	PROPN
fnp-3528	638	40	,	,	PUNCT
fnp-3528	638	41	j.	j.	PROPN
fnp-3528	638	42	;	;	PUNCT
fnp-3528	638	43	naus	naus	PROPN
fnp-3528	638	44	,	,	PUNCT
fnp-3528	638	45	k.	k.	PROPN
fnp-3528	638	46	e.	e.	PROPN
fnp-3528	638	47	;	;	PUNCT
fnp-3528	638	48	mcisaac	mcisaac	PROPN
fnp-3528	638	49	,	,	PUNCT
fnp-3528	638	50	s.	s.	PROPN
fnp-3528	638	51	;	;	PUNCT
fnp-3528	638	52	bromley	bromley	PROPN
fnp-3528	638	53	,	,	PUNCT
fnp-3528	638	54	k.	k.	PROPN
fnp-3528	638	55	;	;	PUNCT
fnp-3528	638	56	song	song	PROPN
fnp-3528	638	57	,	,	PUNCT
fnp-3528	638	58	w.	w.	PROPN
fnp-3528	638	59	;	;	PUNCT
fnp-3528	638	60	yang	yang	PROPN
fnp-3528	638	61	,	,	PUNCT
fnp-3528	638	62	h.	h.	PROPN
fnp-3528	638	63	c.	c.	PROPN
fnp-3528	638	64	;	;	PUNCT
fnp-3528	638	65	wang	wang	PROPN
fnp-3528	638	66	,	,	PUNCT
fnp-3528	638	67	n.	n.	PROPN
fnp-3528	638	68	;	;	PUNCT
fnp-3528	638	69	demattos	demattos	PROPN
fnp-3528	638	70	,	,	PUNCT
fnp-3528	638	71	r.	r.	PROPN
fnp-3528	638	72	b.	b.	PROPN
fnp-3528	638	73	;	;	PUNCT
fnp-3528	638	74	wellington	wellington	PROPN
fnp-3528	638	75	,	,	PUNCT
fnp-3528	638	76	c.	c.	PROPN
fnp-3528	638	77	l.	l.	PROPN
fnp-3528	639	1	the	the	DET
fnp-3528	639	2	cholesterol	cholesterol	NOUN
fnp-3528	639	3	transporter	transporter	NOUN
fnp-3528	639	4	abcg1	abcg1	ADV
fnp-3528	639	5	modulates	modulate	VERB
fnp-3528	639	6	the	the	DET
fnp-3528	639	7	subcellular	subcellular	ADJ
fnp-3528	639	8	distribution	distribution	NOUN
fnp-3528	639	9	and	and	CCONJ
fnp-3528	639	10	proteolytic	proteolytic	ADJ
fnp-3528	639	11	processing	processing	NOUN
fnp-3528	639	12	of	of	ADP
fnp-3528	639	13	beta	beta	NOUN
fnp-3528	639	14	-	-	PUNCT
fnp-3528	639	15	amyloid	amyloid	NOUN
fnp-3528	639	16	precursor	precursor	NOUN
fnp-3528	639	17	protein	protein	NOUN
fnp-3528	639	18	.	.	PUNCT
fnp-3528	640	1	j	j	PROPN
fnp-3528	640	2	lipid	lipid	PROPN
fnp-3528	640	3	res	re	NOUN
fnp-3528	640	4	2007	2007	NUM
fnp-3528	640	5	,	,	PUNCT
fnp-3528	640	6	48	48	NUM
fnp-3528	640	7	,	,	PUNCT
fnp-3528	640	8	1022	1022	NUM
fnp-3528	640	9	-	-	SYM
fnp-3528	640	10	34	34	NUM
fnp-3528	640	11	.	.	PUNCT
fnp-3528	640	12	burgess	burgess	PROPN
fnp-3528	640	13	,	,	PUNCT
fnp-3528	640	14	b.	b.	PROPN
fnp-3528	640	15	l.	l.	PROPN
fnp-3528	640	16	;	;	PUNCT
fnp-3528	640	17	parkinson	parkinson	NOUN
fnp-3528	640	18	,	,	PUNCT
fnp-3528	640	19	p.	p.	PROPN
fnp-3528	640	20	f.	f.	PROPN
fnp-3528	640	21	;	;	PUNCT
fnp-3528	640	22	racke	racke	ADJ
fnp-3528	640	23	,	,	PUNCT
fnp-3528	640	24	m.	m.	NOUN
fnp-3528	640	25	m.	m.	NOUN
fnp-3528	640	26	;	;	PUNCT
fnp-3528	640	27	hirsch	hirsch	PROPN
fnp-3528	640	28	-	-	PUNCT
fnp-3528	640	29	reinshagen	reinshagen	NOUN
fnp-3528	640	30	,	,	PUNCT
fnp-3528	640	31	v.	v.	PROPN
fnp-3528	640	32	;	;	PUNCT
fnp-3528	640	33	fan	fan	PROPN
fnp-3528	640	34	,	,	PUNCT
fnp-3528	640	35	j.	j.	PROPN
fnp-3528	640	36	;	;	PUNCT
fnp-3528	640	37	wong	wong	PROPN
fnp-3528	640	38	,	,	PUNCT
fnp-3528	640	39	c.	c.	PROPN
fnp-3528	640	40	;	;	PUNCT
fnp-3528	640	41	stukas	stukas	PROPN
fnp-3528	640	42	,	,	PUNCT
fnp-3528	640	43	s.	s.	PROPN
fnp-3528	640	44	;	;	PUNCT
fnp-3528	640	45	theroux	theroux	VERB
fnp-3528	640	46	,	,	PUNCT
fnp-3528	640	47	l.	l.	PROPN
fnp-3528	640	48	;	;	PUNCT
fnp-3528	640	49	chan	chan	PROPN
fnp-3528	640	50	,	,	PUNCT
fnp-3528	640	51	j.	j.	PROPN
fnp-3528	640	52	y.	y.	PROPN
fnp-3528	640	53	;	;	PUNCT
fnp-3528	640	54	donkin	donkin	PROPN
fnp-3528	640	55	,	,	PUNCT
fnp-3528	640	56	j.	j.	PROPN
fnp-3528	640	57	;	;	PUNCT
fnp-3528	640	58	wilkinson	wilkinson	PROPN
fnp-3528	640	59	,	,	PUNCT
fnp-3528	640	60	a.	a.	PROPN
fnp-3528	640	61	;	;	PUNCT
fnp-3528	640	62	balik	balik	PROPN
fnp-3528	640	63	,	,	PUNCT
fnp-3528	640	64	d.	d.	PROPN
fnp-3528	640	65	;	;	PUNCT
fnp-3528	640	66	christie	christie	PROPN
fnp-3528	640	67	,	,	PUNCT
fnp-3528	640	68	b.	b.	PROPN
fnp-3528	640	69	;	;	PUNCT
fnp-3528	640	70	poirier	poirier	PROPN
fnp-3528	640	71	,	,	PUNCT
fnp-3528	640	72	j.	j.	PROPN
fnp-3528	640	73	;	;	PUNCT
fnp-3528	640	74	lutjohann	lutjohann	PROPN
fnp-3528	640	75	,	,	PUNCT
fnp-3528	640	76	d.	d.	PROPN
fnp-3528	640	77	;	;	PUNCT
fnp-3528	640	78	demattos	demattos	PROPN
fnp-3528	640	79	,	,	PUNCT
fnp-3528	640	80	r.	r.	PROPN
fnp-3528	640	81	b.	b.	PROPN
fnp-3528	640	82	;	;	PUNCT
fnp-3528	640	83	wellington	wellington	PROPN
fnp-3528	640	84	,	,	PUNCT
fnp-3528	640	85	c.	c.	PROPN
fnp-3528	640	86	l.	l.	PROPN
fnp-3528	640	87	abcg1	abcg1	PROPN
fnp-3528	640	88	influences	influence	VERB
fnp-3528	640	89	the	the	DET
fnp-3528	640	90	brain	brain	NOUN
fnp-3528	640	91	cholesterol	cholesterol	NOUN
fnp-3528	640	92	biosynthetic	biosynthetic	ADJ
fnp-3528	640	93	pathway	pathway	NOUN
fnp-3528	640	94	but	but	CCONJ
fnp-3528	640	95	does	do	AUX
fnp-3528	640	96	not	not	PART
fnp-3528	640	97	affect	affect	VERB
fnp-3528	640	98	amyloid	amyloid	NOUN
fnp-3528	640	99	precursor	precursor	NOUN
fnp-3528	640	100	protein	protein	NOUN
fnp-3528	640	101	or	or	CCONJ
fnp-3528	640	102	apolipoprotein	apolipoprotein	VERB
fnp-3528	640	103	e	e	VERB
fnp-3528	640	104	metabolism	metabolism	NOUN
fnp-3528	640	105	in	in	ADP
fnp-3528	640	106	vivo	vivo	NOUN
fnp-3528	640	107	.	.	PUNCT
fnp-3528	641	1	j	j	PROPN
fnp-3528	641	2	lipid	lipid	PROPN
fnp-3528	641	3	res	re	NOUN
fnp-3528	641	4	2008	2008	NUM
fnp-3528	641	5	,	,	PUNCT
fnp-3528	641	6	49	49	NUM
fnp-3528	641	7	,	,	PUNCT
fnp-3528	641	8	1254	1254	NUM
fnp-3528	641	9	-	-	SYM
fnp-3528	641	10	67	67	NUM
fnp-3528	641	11	.	.	PUNCT
fnp-3528	642	1	shen	shen	PROPN
fnp-3528	642	2	,	,	PUNCT
fnp-3528	642	3	s.	s.	PROPN
fnp-3528	642	4	;	;	PUNCT
fnp-3528	642	5	callaghan	callaghan	PROPN
fnp-3528	642	6	,	,	PUNCT
fnp-3528	642	7	d.	d.	PROPN
fnp-3528	642	8	;	;	PUNCT
fnp-3528	642	9	juzwik	juzwik	PROPN
fnp-3528	642	10	,	,	PUNCT
fnp-3528	642	11	c.	c.	PROPN
fnp-3528	642	12	;	;	PUNCT
fnp-3528	642	13	xiong	xiong	PROPN
fnp-3528	642	14	,	,	PUNCT
fnp-3528	642	15	h.	h.	PROPN
fnp-3528	642	16	;	;	PUNCT
fnp-3528	642	17	huang	huang	PROPN
fnp-3528	642	18	,	,	PUNCT
fnp-3528	642	19	p.	p.	PROPN
fnp-3528	642	20	;	;	PUNCT
fnp-3528	642	21	zhang	zhang	PROPN
fnp-3528	642	22	,	,	PUNCT
fnp-3528	642	23	w.	w.	PROPN
fnp-3528	642	24	abcg2	abcg2	PROPN
fnp-3528	642	25	reduces	reduce	VERB
fnp-3528	642	26	ros	ros	PROPN
fnp-3528	642	27	-	-	PUNCT
fnp-3528	642	28	mediated	mediate	VERB
fnp-3528	642	29	toxicity	toxicity	NOUN
fnp-3528	642	30	and	and	CCONJ
fnp-3528	642	31	inflammation	inflammation	NOUN
fnp-3528	642	32	:	:	PUNCT
fnp-3528	642	33	a	a	DET
fnp-3528	642	34	potential	potential	ADJ
fnp-3528	642	35	role	role	NOUN
fnp-3528	642	36	in	in	ADP
fnp-3528	642	37	alzheimer	alzheimer	PROPN
fnp-3528	642	38	's	's	PART
fnp-3528	642	39	disease	disease	NOUN
fnp-3528	642	40	.	.	PUNCT
fnp-3528	643	1	j	j	PROPN
fnp-3528	643	2	neurochem	neurochem	PROPN
fnp-3528	643	3	2010	2010	NUM
fnp-3528	643	4	,	,	PUNCT
fnp-3528	643	5	114	114	NUM
fnp-3528	643	6	,	,	PUNCT
fnp-3528	643	7	1590	1590	NUM
fnp-3528	643	8	-	-	SYM
fnp-3528	643	9	604	604	NUM
fnp-3528	643	10	.	.	PUNCT
fnp-3528	644	1	van	van	PROPN
fnp-3528	644	2	vliet	vliet	PROPN
fnp-3528	644	3	,	,	PUNCT
fnp-3528	644	4	e.	e.	PROPN
fnp-3528	644	5	a.	a.	PROPN
fnp-3528	644	6	;	;	PUNCT
fnp-3528	644	7	iyer	iyer	PROPN
fnp-3528	644	8	,	,	PUNCT
fnp-3528	644	9	a.	a.	NOUN
fnp-3528	644	10	m.	m.	NOUN
fnp-3528	644	11	;	;	PUNCT
fnp-3528	644	12	mesarosova	mesarosova	PROPN
fnp-3528	644	13	,	,	PUNCT
fnp-3528	644	14	l.	l.	PROPN
fnp-3528	644	15	;	;	PUNCT
fnp-3528	644	16	colakoglu	colakoglu	PROPN
fnp-3528	644	17	,	,	PUNCT
fnp-3528	644	18	h.	h.	PROPN
fnp-3528	644	19	;	;	PUNCT
fnp-3528	644	20	anink	anink	NOUN
fnp-3528	644	21	,	,	PUNCT
fnp-3528	644	22	j.	j.	PROPN
fnp-3528	644	23	j.	j.	PROPN
fnp-3528	644	24	;	;	PUNCT
fnp-3528	644	25	van	van	PROPN
fnp-3528	644	26	tellingen	tellingen	PROPN
fnp-3528	644	27	,	,	PUNCT
fnp-3528	644	28	o.	o.	PROPN
fnp-3528	644	29	;	;	PUNCT
fnp-3528	644	30	maragakis	maragakis	PROPN
fnp-3528	644	31	,	,	PUNCT
fnp-3528	644	32	n.	n.	PROPN
fnp-3528	644	33	j.	j.	PROPN
fnp-3528	644	34	;	;	PUNCT
fnp-3528	644	35	shefner	shefner	NOUN
fnp-3528	644	36	,	,	PUNCT
fnp-3528	644	37	j.	j.	PROPN
fnp-3528	644	38	;	;	PUNCT
fnp-3528	644	39	bunt	bunt	PROPN
fnp-3528	644	40	,	,	PUNCT
fnp-3528	644	41	t.	t.	PROPN
fnp-3528	644	42	;	;	PUNCT
fnp-3528	644	43	aronica	aronica	PROPN
fnp-3528	644	44	,	,	PUNCT
fnp-3528	644	45	e.	e.	PROPN
fnp-3528	644	46	expression	expression	NOUN
fnp-3528	644	47	and	and	CCONJ
fnp-3528	644	48	cellular	cellular	ADJ
fnp-3528	644	49	distribution	distribution	NOUN
fnp-3528	644	50	of	of	ADP
fnp-3528	644	51	p	p	NOUN
fnp-3528	644	52	-	-	PUNCT
fnp-3528	644	53	glycoprotein	glycoprotein	NOUN
fnp-3528	644	54	and	and	CCONJ
fnp-3528	644	55	breast	breast	NOUN
fnp-3528	644	56	cancer	cancer	NOUN
fnp-3528	644	57	resistance	resistance	NOUN
fnp-3528	644	58	protein	protein	NOUN
fnp-3528	644	59	in	in	ADP
fnp-3528	644	60	amyotrophic	amyotrophic	ADJ
fnp-3528	644	61	lateral	lateral	ADJ
fnp-3528	644	62	sclerosis	sclerosis	NOUN
fnp-3528	644	63	patients	patient	NOUN
fnp-3528	644	64	.	.	PUNCT
fnp-3528	645	1	j	j	PROPN
fnp-3528	645	2	neuropathol	neuropathol	PROPN
fnp-3528	645	3	exp	exp	PROPN
fnp-3528	645	4	neurol	neurol	PROPN
fnp-3528	645	5	2020	2020	NUM
fnp-3528	645	6	,	,	PUNCT
fnp-3528	645	7	79	79	NUM
fnp-3528	645	8	,	,	PUNCT
fnp-3528	645	9	266	266	NUM
fnp-3528	645	10	-	-	SYM
fnp-3528	645	11	276	276	NUM
fnp-3528	645	12	.	.	PUNCT
fnp-3528	646	1	bleau	bleau	NOUN
fnp-3528	646	2	,	,	PUNCT
fnp-3528	646	3	a.	a.	NOUN
fnp-3528	646	4	m.	m.	NOUN
fnp-3528	646	5	;	;	PUNCT
fnp-3528	646	6	hambardzumyan	hambardzumyan	PROPN
fnp-3528	646	7	,	,	PUNCT
fnp-3528	646	8	d.	d.	PROPN
fnp-3528	646	9	;	;	PUNCT
fnp-3528	646	10	ozawa	ozawa	PROPN
fnp-3528	646	11	,	,	PUNCT
fnp-3528	646	12	t.	t.	PROPN
fnp-3528	646	13	;	;	PUNCT
fnp-3528	646	14	fomchenko	fomchenko	PROPN
fnp-3528	646	15	,	,	PUNCT
fnp-3528	646	16	e.	e.	PROPN
fnp-3528	646	17	i.	i.	PROPN
fnp-3528	646	18	;	;	PUNCT
fnp-3528	646	19	huse	huse	NOUN
fnp-3528	646	20	,	,	PUNCT
fnp-3528	646	21	j.	j.	PROPN
fnp-3528	646	22	t.	t.	PROPN
fnp-3528	646	23	;	;	PUNCT
fnp-3528	646	24	brennan	brennan	PROPN
fnp-3528	646	25	,	,	PUNCT
fnp-3528	646	26	c.	c.	PROPN
fnp-3528	646	27	w.	w.	PROPN
fnp-3528	646	28	;	;	PUNCT
fnp-3528	646	29	holland	holland	PROPN
fnp-3528	646	30	,	,	PUNCT
fnp-3528	646	31	e.	e.	PROPN
fnp-3528	646	32	c.	c.	PROPN
fnp-3528	646	33	pten	pten	PROPN
fnp-3528	646	34	/	/	SYM
fnp-3528	646	35	pi3k	pi3k	PROPN
fnp-3528	646	36	/	/	SYM
fnp-3528	646	37	akt	akt	PROPN
fnp-3528	646	38	pathway	pathway	NOUN
fnp-3528	646	39	regulates	regulate	VERB
fnp-3528	646	40	the	the	DET
fnp-3528	646	41	side	side	ADJ
fnp-3528	646	42	population	population	NOUN
fnp-3528	646	43	phenotype	phenotype	NOUN
fnp-3528	646	44	and	and	CCONJ
fnp-3528	646	45	abcg2	abcg2	NOUN
fnp-3528	646	46	activity	activity	NOUN
fnp-3528	646	47	in	in	ADP
fnp-3528	646	48	glioma	glioma	NOUN
fnp-3528	646	49	tumor	tumor	NOUN
fnp-3528	646	50	stem	stem	NOUN
fnp-3528	646	51	-	-	PUNCT
fnp-3528	646	52	like	like	ADJ
fnp-3528	646	53	cells	cell	NOUN
fnp-3528	646	54	.	.	PUNCT
fnp-3528	647	1	cell	cell	NOUN
fnp-3528	647	2	stem	stem	NOUN
fnp-3528	647	3	cell	cell	NOUN
fnp-3528	647	4	2009	2009	NUM
fnp-3528	647	5	,	,	PUNCT
fnp-3528	647	6	4	4	NUM
fnp-3528	647	7	,	,	PUNCT
fnp-3528	647	8	226	226	NUM
fnp-3528	647	9	-	-	SYM
fnp-3528	647	10	35	35	NUM
fnp-3528	647	11	.	.	PUNCT
fnp-3528	648	1	van	van	PROPN
fnp-3528	648	2	vliet	vliet	PROPN
fnp-3528	648	3	,	,	PUNCT
fnp-3528	648	4	e.	e.	PROPN
fnp-3528	648	5	a.	a.	PROPN
fnp-3528	648	6	;	;	PUNCT
fnp-3528	648	7	redeker	redeker	PROPN
fnp-3528	648	8	,	,	PUNCT
fnp-3528	648	9	s.	s.	PROPN
fnp-3528	648	10	;	;	PUNCT
fnp-3528	648	11	aronica	aronica	PROPN
fnp-3528	648	12	,	,	PUNCT
fnp-3528	648	13	e.	e.	PROPN
fnp-3528	648	14	;	;	PUNCT
fnp-3528	648	15	edelbroek	edelbroek	PROPN
fnp-3528	648	16	,	,	PUNCT
fnp-3528	648	17	p.	p.	NOUN
fnp-3528	648	18	m.	m.	NOUN
fnp-3528	648	19	;	;	PUNCT
fnp-3528	648	20	gorter	gorter	NOUN
fnp-3528	648	21	,	,	PUNCT
fnp-3528	648	22	j.	j.	PROPN
fnp-3528	648	23	a.	a.	NOUN
fnp-3528	648	24	expression	expression	NOUN
fnp-3528	648	25	of	of	ADP
fnp-3528	648	26	multidrug	multidrug	NOUN
fnp-3528	648	27	transporters	transporter	NOUN
fnp-3528	648	28	mrp1	mrp1	NOUN
fnp-3528	648	29	,	,	PUNCT
fnp-3528	648	30	mrp2	mrp2	PROPN
fnp-3528	648	31	,	,	PUNCT
fnp-3528	648	32	and	and	CCONJ
fnp-3528	648	33	bcrp	bcrp	ADV
fnp-3528	648	34	shortly	shortly	ADV
fnp-3528	648	35	after	after	SCONJ
fnp-3528	648	36	status	status	NOUN
fnp-3528	648	37	epilepticus	epilepticus	VERB
fnp-3528	648	38	,	,	PUNCT
fnp-3528	648	39	during	during	ADP
fnp-3528	648	40	the	the	DET
fnp-3528	648	41	latent	latent	NOUN
fnp-3528	648	42	period	period	NOUN
fnp-3528	648	43	,	,	PUNCT
fnp-3528	648	44	and	and	CCONJ
fnp-3528	648	45	in	in	ADP
fnp-3528	648	46	chronic	chronic	ADJ
fnp-3528	648	47	epileptic	epileptic	ADJ
fnp-3528	648	48	rats	rat	NOUN
fnp-3528	648	49	.	.	PUNCT
fnp-3528	649	1	epilepsia	epilepsia	NOUN
fnp-3528	649	2	2005	2005	NUM
fnp-3528	649	3	,	,	PUNCT
fnp-3528	649	4	46	46	NUM
fnp-3528	649	5	,	,	PUNCT
fnp-3528	649	6	1569	1569	NUM
fnp-3528	649	7	-	-	SYM
fnp-3528	649	8	80	80	NUM
fnp-3528	649	9	.	.	PUNCT
fnp-3528	650	1	kooij	kooij	PROPN
fnp-3528	650	2	,	,	PUNCT
fnp-3528	650	3	g.	g.	PROPN
fnp-3528	650	4	;	;	PUNCT
fnp-3528	650	5	mizee	mizee	PROPN
fnp-3528	650	6	,	,	PUNCT
fnp-3528	650	7	m.	m.	PROPN
fnp-3528	650	8	r.	r.	PROPN
fnp-3528	650	9	;	;	PUNCT
fnp-3528	650	10	van	van	PROPN
fnp-3528	650	11	horssen	horssen	PROPN
fnp-3528	650	12	,	,	PUNCT
fnp-3528	650	13	j.	j.	PROPN
fnp-3528	650	14	;	;	PUNCT
fnp-3528	650	15	reijerkerk	reijerkerk	PROPN
fnp-3528	650	16	,	,	PUNCT
fnp-3528	650	17	a.	a.	NOUN
fnp-3528	650	18	;	;	PUNCT
fnp-3528	650	19	witte	witte	NOUN
fnp-3528	650	20	,	,	PUNCT
fnp-3528	650	21	m.	m.	PROPN
fnp-3528	650	22	e.	e.	PROPN
fnp-3528	650	23	;	;	PUNCT
fnp-3528	650	24	drexhage	drexhage	PROPN
fnp-3528	650	25	,	,	PUNCT
fnp-3528	650	26	j.	j.	PROPN
fnp-3528	650	27	a.	a.	PROPN
fnp-3528	650	28	;	;	PUNCT
fnp-3528	650	29	van	van	PROPN
fnp-3528	650	30	der	der	PROPN
fnp-3528	650	31	pol	pol	PROPN
fnp-3528	650	32	,	,	PUNCT
fnp-3528	650	33	s.	s.	PROPN
fnp-3528	650	34	m.	m.	PROPN
fnp-3528	650	35	;	;	PUNCT
fnp-3528	650	36	van	van	PROPN
fnp-3528	650	37	het	het	PROPN
fnp-3528	650	38	hof	hof	PROPN
fnp-3528	650	39	,	,	PUNCT
fnp-3528	650	40	b.	b.	PROPN
fnp-3528	650	41	;	;	PUNCT
fnp-3528	650	42	scheffer	scheffer	PROPN
fnp-3528	650	43	,	,	PUNCT
fnp-3528	650	44	g.	g.	PROPN
fnp-3528	650	45	;	;	PUNCT
fnp-3528	650	46	scheper	scheper	PROPN
fnp-3528	650	47	,	,	PUNCT
fnp-3528	650	48	r.	r.	PROPN
fnp-3528	650	49	;	;	PUNCT
fnp-3528	650	50	dijkstra	dijkstra	PROPN
fnp-3528	650	51	,	,	PUNCT
fnp-3528	650	52	c.	c.	PROPN
fnp-3528	650	53	d.	d.	PROPN
fnp-3528	650	54	;	;	PUNCT
fnp-3528	650	55	van	van	PROPN
fnp-3528	650	56	der	der	PROPN
fnp-3528	650	57	valk	valk	PROPN
fnp-3528	650	58	,	,	PUNCT
fnp-3528	650	59	p.	p.	NOUN
fnp-3528	650	60	;	;	PUNCT
fnp-3528	650	61	de	de	PROPN
fnp-3528	650	62	vries	vries	PROPN
fnp-3528	650	63	,	,	PUNCT
fnp-3528	650	64	h.	h.	PROPN
fnp-3528	650	65	e.	e.	PROPN
fnp-3528	650	66	adenosine	adenosine	PROPN
fnp-3528	650	67	triphosphate	triphosphate	NOUN
fnp-3528	650	68	-	-	PUNCT
fnp-3528	650	69	binding	bind	VERB
fnp-3528	650	70	cassette	cassette	NOUN
fnp-3528	650	71	transporters	transporter	NOUN
fnp-3528	650	72	mediate	mediate	VERB
fnp-3528	650	73	chemokine	chemokine	ADJ
fnp-3528	650	74	(	(	PUNCT
fnp-3528	650	75	c	c	NOUN
fnp-3528	650	76	-	-	PUNCT
fnp-3528	650	77	c	c	NOUN
fnp-3528	650	78	motif	motif	NOUN
fnp-3528	650	79	)	)	PUNCT
fnp-3528	650	80	ligand	ligand	NOUN
fnp-3528	650	81	2	2	NUM
fnp-3528	650	82	secretion	secretion	NOUN
fnp-3528	650	83	from	from	ADP
fnp-3528	650	84	reactive	reactive	ADJ
fnp-3528	650	85	astrocytes	astrocyte	NOUN
fnp-3528	650	86	:	:	PUNCT
fnp-3528	650	87	relevance	relevance	NOUN
fnp-3528	650	88	to	to	ADP
fnp-3528	650	89	multiple	multiple	ADJ
fnp-3528	650	90	sclerosis	sclerosis	NOUN
fnp-3528	650	91	pathogenesis	pathogenesis	NOUN
fnp-3528	650	92	.	.	PUNCT
fnp-3528	651	1	brain	brain	NOUN
fnp-3528	651	2	2011	2011	NUM
fnp-3528	651	3	,	,	PUNCT
fnp-3528	651	4	134	134	NUM
fnp-3528	651	5	,	,	PUNCT
fnp-3528	651	6	555	555	NUM
fnp-3528	651	7	-	-	SYM
fnp-3528	651	8	70	70	NUM
fnp-3528	651	9	.	.	PUNCT
fnp-3528	652	1	adams	adams	PROPN
fnp-3528	652	2	,	,	PUNCT
fnp-3528	652	3	s.	s.	PROPN
fnp-3528	652	4	m.	m.	PROPN
fnp-3528	652	5	;	;	PUNCT
fnp-3528	652	6	conley	conley	PROPN
fnp-3528	652	7	,	,	PUNCT
fnp-3528	652	8	y.	y.	PROPN
fnp-3528	652	9	p.	p.	PROPN
fnp-3528	652	10	;	;	PUNCT
fnp-3528	652	11	ren	ren	PROPN
fnp-3528	652	12	,	,	PUNCT
fnp-3528	652	13	d.	d.	PROPN
fnp-3528	652	14	;	;	PUNCT
fnp-3528	652	15	okonkwo	okonkwo	PROPN
fnp-3528	652	16	,	,	PUNCT
fnp-3528	652	17	d.	d.	PROPN
fnp-3528	652	18	o.	o.	PROPN
fnp-3528	652	19	;	;	PUNCT
fnp-3528	652	20	puccio	puccio	PROPN
fnp-3528	652	21	,	,	PUNCT
fnp-3528	652	22	a.	a.	NOUN
fnp-3528	652	23	m.	m.	NOUN
fnp-3528	652	24	;	;	PUNCT
fnp-3528	652	25	dixon	dixon	PROPN
fnp-3528	652	26	,	,	PUNCT
fnp-3528	652	27	c.	c.	PROPN
fnp-3528	652	28	e.	e.	PROPN
fnp-3528	652	29	;	;	PUNCT
fnp-3528	652	30	clark	clark	PROPN
fnp-3528	652	31	,	,	PUNCT
fnp-3528	652	32	r.	r.	PROPN
fnp-3528	652	33	s.	s.	PROPN
fnp-3528	652	34	b.	b.	PROPN
fnp-3528	652	35	;	;	PUNCT
fnp-3528	652	36	kochanek	kochanek	NOUN
fnp-3528	652	37	,	,	PUNCT
fnp-3528	652	38	p.	p.	NOUN
fnp-3528	652	39	m.	m.	NOUN
fnp-3528	652	40	;	;	PUNCT
fnp-3528	652	41	empey	empey	PROPN
fnp-3528	652	42	,	,	PUNCT
fnp-3528	652	43	p.	p.	NOUN
fnp-3528	652	44	e.	e.	PROPN
fnp-3528	652	45	abcg2	abcg2	PUNCT
fnp-3528	653	1	c.421c	c.421c	PROPN
fnp-3528	653	2	>	>	X
fnp-3528	653	3	a	a	PRON
fnp-3528	653	4	is	be	AUX
fnp-3528	653	5	associated	associate	VERB
fnp-3528	653	6	with	with	ADP
fnp-3528	653	7	outcomes	outcome	NOUN
fnp-3528	653	8	after	after	ADP
fnp-3528	653	9	severe	severe	ADJ
fnp-3528	653	10	traumatic	traumatic	ADJ
fnp-3528	653	11	brain	brain	NOUN
fnp-3528	653	12	injury	injury	NOUN
fnp-3528	653	13	.	.	PUNCT
fnp-3528	654	1	j	j	PROPN
fnp-3528	654	2	neurotrauma	neurotrauma	PROPN
fnp-3528	654	3	2018	2018	NUM
fnp-3528	654	4	,	,	PUNCT
fnp-3528	654	5	35	35	NUM
fnp-3528	654	6	,	,	PUNCT
fnp-3528	654	7	48	48	NUM
fnp-3528	654	8	-	-	SYM
fnp-3528	654	9	53	53	NUM
fnp-3528	654	10	.	.	PUNCT
fnp-3528	655	1	do	do	VERB
fnp-3528	655	2	,	,	PUNCT
fnp-3528	655	3	t.	t.	NOUN
fnp-3528	655	4	m.	m.	NOUN
fnp-3528	655	5	;	;	PUNCT
fnp-3528	655	6	noel	noel	PROPN
fnp-3528	655	7	-	-	PUNCT
fnp-3528	655	8	hudson	hudson	PROPN
fnp-3528	655	9	,	,	PUNCT
fnp-3528	655	10	m.	m.	PROPN
fnp-3528	655	11	s.	s.	PROPN
fnp-3528	655	12	;	;	PUNCT
fnp-3528	655	13	ribes	ribe	NOUN
fnp-3528	655	14	,	,	PUNCT
fnp-3528	655	15	s.	s.	PROPN
fnp-3528	655	16	;	;	PUNCT
fnp-3528	655	17	besengez	besengez	PROPN
fnp-3528	655	18	,	,	PUNCT
fnp-3528	655	19	c.	c.	NOUN
fnp-3528	655	20	;	;	PUNCT
fnp-3528	655	21	smirnova	smirnova	NOUN
fnp-3528	655	22	,	,	PUNCT
fnp-3528	655	23	m.	m.	NOUN
fnp-3528	655	24	;	;	PUNCT
fnp-3528	655	25	cisternino	cisternino	PROPN
fnp-3528	655	26	,	,	PUNCT
fnp-3528	655	27	s.	s.	PROPN
fnp-3528	655	28	;	;	PUNCT
fnp-3528	655	29	buyse	buyse	NOUN
fnp-3528	655	30	,	,	PUNCT
fnp-3528	655	31	m.	m.	NOUN
fnp-3528	655	32	;	;	PUNCT
fnp-3528	655	33	calon	calon	PROPN
fnp-3528	655	34	,	,	PUNCT
fnp-3528	655	35	f.	f.	PROPN
fnp-3528	655	36	;	;	PUNCT
fnp-3528	655	37	chimini	chimini	PROPN
fnp-3528	655	38	,	,	PUNCT
fnp-3528	655	39	g.	g.	PROPN
fnp-3528	655	40	;	;	PUNCT
fnp-3528	655	41	chacun	chacun	PROPN
fnp-3528	655	42	,	,	PUNCT
fnp-3528	655	43	h.	h.	PROPN
fnp-3528	655	44	;	;	PUNCT
fnp-3528	655	45	scherrmann	scherrmann	PROPN
fnp-3528	655	46	,	,	PUNCT
fnp-3528	655	47	j.	j.	PROPN
fnp-3528	655	48	m.	m.	PROPN
fnp-3528	655	49	;	;	PUNCT
fnp-3528	655	50	farinotti	farinotti	PROPN
fnp-3528	655	51	,	,	PUNCT
fnp-3528	655	52	r.	r.	PROPN
fnp-3528	655	53	;	;	PUNCT
fnp-3528	655	54	bourasset	bourasset	PROPN
fnp-3528	655	55	,	,	PUNCT
fnp-3528	655	56	f.	f.	PROPN
fnp-3528	655	57	abcg2and	abcg2and	PUNCT
fnp-3528	655	58	abcg4	abcg4	PROPN
fnp-3528	655	59	-	-	PUNCT
fnp-3528	655	60	mediated	mediate	VERB
fnp-3528	655	61	efflux	efflux	NOUN
fnp-3528	655	62	of	of	ADP
fnp-3528	655	63	amyloid	amyloid	NOUN
fnp-3528	655	64	-	-	PUNCT
fnp-3528	655	65	beta	beta	NOUN
fnp-3528	655	66	peptide	peptide	NOUN
fnp-3528	655	67	1	1	NUM
fnp-3528	655	68	-	-	SYM
fnp-3528	655	69	40	40	NUM
fnp-3528	655	70	at	at	ADP
fnp-3528	655	71	the	the	DET
fnp-3528	655	72	mouse	mouse	NOUN
fnp-3528	655	73	blood	blood	NOUN
fnp-3528	655	74	-	-	PUNCT
fnp-3528	655	75	brain	brain	NOUN
fnp-3528	655	76	barrier	barrier	NOUN
fnp-3528	655	77	.	.	PUNCT
fnp-3528	656	1	j	j	PROPN
fnp-3528	656	2	alzheimers	alzheimers	PROPN
fnp-3528	656	3	dis	dis	PROPN
fnp-3528	656	4	2012	2012	NUM
fnp-3528	656	5	,	,	PUNCT
fnp-3528	656	6	30	30	NUM
fnp-3528	656	7	,	,	PUNCT
fnp-3528	656	8	155	155	NUM
fnp-3528	656	9	-	-	SYM
fnp-3528	656	10	66	66	NUM
fnp-3528	656	11	.	.	PUNCT
fnp-3528	657	1	lam	lam	PROPN
fnp-3528	657	2	,	,	PUNCT
fnp-3528	657	3	f.	f.	PROPN
fnp-3528	657	4	c.	c.	PROPN
fnp-3528	657	5	;	;	PUNCT
fnp-3528	657	6	liu	liu	PROPN
fnp-3528	657	7	,	,	PUNCT
fnp-3528	657	8	r.	r.	PROPN
fnp-3528	657	9	;	;	PUNCT
fnp-3528	657	10	lu	lu	PROPN
fnp-3528	657	11	,	,	PUNCT
fnp-3528	657	12	p.	p.	NOUN
fnp-3528	657	13	;	;	PUNCT
fnp-3528	657	14	shapiro	shapiro	PROPN
fnp-3528	657	15	,	,	PUNCT
fnp-3528	657	16	a.	a.	PROPN
fnp-3528	657	17	b.	b.	PROPN
fnp-3528	657	18	;	;	PUNCT
fnp-3528	657	19	renoir	renoir	PROPN
fnp-3528	657	20	,	,	PUNCT
fnp-3528	657	21	j.	j.	PROPN
fnp-3528	657	22	m.	m.	PROPN
fnp-3528	657	23	;	;	PUNCT
fnp-3528	657	24	sharom	sharom	PROPN
fnp-3528	657	25	,	,	PUNCT
fnp-3528	657	26	f.	f.	PROPN
fnp-3528	657	27	j.	j.	PROPN
fnp-3528	657	28	;	;	PUNCT
fnp-3528	657	29	reiner	reiner	NOUN
fnp-3528	657	30	,	,	PUNCT
fnp-3528	657	31	p.	p.	PROPN
fnp-3528	657	32	b.	b.	PROPN
fnp-3528	658	1	beta	beta	NOUN
fnp-3528	658	2	-	-	PUNCT
fnp-3528	658	3	amyloid	amyloid	NOUN
fnp-3528	658	4	efflux	efflux	NOUN
fnp-3528	658	5	mediated	mediate	VERB
fnp-3528	658	6	by	by	ADP
fnp-3528	658	7	p	p	NOUN
fnp-3528	658	8	-	-	PUNCT
fnp-3528	658	9	glycoprotein	glycoprotein	NOUN
fnp-3528	658	10	.	.	PUNCT
fnp-3528	659	1	j	j	PROPN
fnp-3528	659	2	neurochem	neurochem	PROPN
fnp-3528	659	3	2001	2001	NUM
fnp-3528	659	4	,	,	PUNCT
fnp-3528	659	5	76	76	NUM
fnp-3528	659	6	,	,	PUNCT
fnp-3528	659	7	1121	1121	NUM
fnp-3528	659	8	-	-	SYM
fnp-3528	659	9	8	8	NUM
fnp-3528	659	10	.	.	PUNCT
fnp-3528	659	11	piehler	piehler	NOUN
fnp-3528	659	12	,	,	PUNCT
fnp-3528	659	13	a.	a.	NOUN
fnp-3528	659	14	p.	p.	NOUN
fnp-3528	659	15	;	;	PUNCT
fnp-3528	660	1	ozcurumez	ozcurumez	NOUN
fnp-3528	660	2	,	,	PUNCT
fnp-3528	660	3	m.	m.	NOUN
fnp-3528	660	4	;	;	PUNCT
fnp-3528	660	5	kaminski	kaminski	PROPN
fnp-3528	660	6	,	,	PUNCT
fnp-3528	660	7	w.	w.	PROPN
fnp-3528	660	8	e.	e.	PROPN
fnp-3528	660	9	a	a	PROPN
fnp-3528	660	10	-	-	PUNCT
fnp-3528	660	11	subclass	subclass	NOUN
fnp-3528	660	12	atp	atp	NOUN
fnp-3528	660	13	-	-	PUNCT
fnp-3528	660	14	binding	bind	VERB
fnp-3528	660	15	cassette	cassette	NOUN
fnp-3528	660	16	proteins	protein	NOUN
fnp-3528	660	17	in	in	ADP
fnp-3528	660	18	brain	brain	NOUN
fnp-3528	660	19	lipid	lipid	NOUN
fnp-3528	660	20	homeostasis	homeostasis	NOUN
fnp-3528	660	21	and	and	CCONJ
fnp-3528	660	22	neurodegeneration	neurodegeneration	NOUN
fnp-3528	660	23	.	.	PUNCT
fnp-3528	661	1	front	front	ADJ
fnp-3528	661	2	psychiatry	psychiatry	NOUN
fnp-3528	661	3	2012	2012	NUM
fnp-3528	661	4	,	,	PUNCT
fnp-3528	661	5	3	3	NUM
fnp-3528	661	6	,	,	PUNCT
fnp-3528	661	7	17	17	NUM
fnp-3528	661	8	.	.	PUNCT
fnp-3528	662	1	krohn	krohn	PROPN
fnp-3528	662	2	,	,	PUNCT
fnp-3528	662	3	m.	m.	NOUN
fnp-3528	662	4	;	;	PUNCT
fnp-3528	662	5	lange	lange	PROPN
fnp-3528	662	6	,	,	PUNCT
fnp-3528	662	7	c.	c.	NOUN
fnp-3528	662	8	;	;	PUNCT
fnp-3528	662	9	hofrichter	hofrichter	PROPN
fnp-3528	662	10	,	,	PUNCT
fnp-3528	662	11	j.	j.	PROPN
fnp-3528	662	12	;	;	PUNCT
fnp-3528	662	13	scheffler	scheffler	PROPN
fnp-3528	662	14	,	,	PUNCT
fnp-3528	662	15	k.	k.	PROPN
fnp-3528	662	16	;	;	PUNCT
fnp-3528	662	17	stenzel	stenzel	PROPN
fnp-3528	662	18	,	,	PUNCT
fnp-3528	662	19	j.	j.	PROPN
fnp-3528	662	20	;	;	PUNCT
fnp-3528	662	21	steffen	steffen	PROPN
fnp-3528	662	22	,	,	PUNCT
fnp-3528	662	23	j.	j.	PROPN
fnp-3528	662	24	;	;	PUNCT
fnp-3528	662	25	schumacher	schumacher	PROPN
fnp-3528	662	26	,	,	PUNCT
fnp-3528	662	27	t.	t.	PROPN
fnp-3528	662	28	;	;	PUNCT
fnp-3528	662	29	bruning	brune	VERB
fnp-3528	662	30	,	,	PUNCT
fnp-3528	662	31	t.	t.	PROPN
fnp-3528	662	32	;	;	PUNCT
fnp-3528	662	33	plath	plath	NOUN
fnp-3528	662	34	,	,	PUNCT
fnp-3528	662	35	a.	a.	PROPN
fnp-3528	662	36	s.	s.	PROPN
fnp-3528	662	37	;	;	PUNCT
fnp-3528	662	38	alfen	alfen	PROPN
fnp-3528	662	39	,	,	PUNCT
fnp-3528	662	40	f.	f.	PROPN
fnp-3528	662	41	;	;	PUNCT
fnp-3528	662	42	schmidt	schmidt	PROPN
fnp-3528	662	43	,	,	PUNCT
fnp-3528	662	44	a.	a.	NOUN
fnp-3528	662	45	;	;	PUNCT
fnp-3528	662	46	winter	winter	PROPN
fnp-3528	662	47	,	,	PUNCT
fnp-3528	662	48	f.	f.	PROPN
fnp-3528	662	49	;	;	PUNCT
fnp-3528	662	50	rateitschak	rateitschak	ADJ
fnp-3528	662	51	,	,	PUNCT
fnp-3528	662	52	k.	k.	PROPN
fnp-3528	662	53	;	;	PUNCT
fnp-3528	662	54	wree	wree	PROPN
fnp-3528	662	55	,	,	PUNCT
fnp-3528	662	56	a.	a.	NOUN
fnp-3528	662	57	;	;	PUNCT
fnp-3528	662	58	gsponer	gsponer	NOUN
fnp-3528	662	59	,	,	PUNCT
fnp-3528	662	60	j.	j.	PROPN
fnp-3528	662	61	;	;	PUNCT
fnp-3528	662	62	walker	walker	PROPN
fnp-3528	662	63	,	,	PUNCT
fnp-3528	662	64	l.	l.	PROPN
fnp-3528	662	65	c.	c.	PROPN
fnp-3528	662	66	;	;	PUNCT
fnp-3528	662	67	pahnke	pahnke	PROPN
fnp-3528	662	68	,	,	PUNCT
fnp-3528	662	69	j.	j.	PROPN
fnp-3528	662	70	cerebral	cerebral	ADJ
fnp-3528	662	71	amyloid	amyloid	NOUN
fnp-3528	662	72	-	-	PUNCT
fnp-3528	662	73	beta	beta	NOUN
fnp-3528	662	74	proteostasis	proteostasis	NOUN
fnp-3528	662	75	is	be	AUX
fnp-3528	662	76	regulated	regulate	VERB
fnp-3528	662	77	by	by	ADP
fnp-3528	662	78	the	the	DET
fnp-3528	662	79	membrane	membrane	NOUN
fnp-3528	662	80	transport	transport	NOUN
fnp-3528	662	81	protein	protein	NOUN
fnp-3528	662	82	abcc1	abcc1	VERB
fnp-3528	662	83	in	in	ADP
fnp-3528	662	84	mice	mouse	NOUN
fnp-3528	662	85	.	.	PUNCT
fnp-3528	663	1	j	j	PROPN
fnp-3528	663	2	clin	clin	PROPN
fnp-3528	663	3	invest	invest	VERB
fnp-3528	663	4	2011	2011	NUM
fnp-3528	663	5	,	,	PUNCT
fnp-3528	663	6	121	121	NUM
fnp-3528	663	7	,	,	PUNCT
fnp-3528	663	8	3924	3924	NUM
fnp-3528	663	9	-	-	SYM
fnp-3528	663	10	31	31	NUM
fnp-3528	663	11	.	.	PUNCT
fnp-3528	664	1	xiong	xiong	PROPN
fnp-3528	664	2	,	,	PUNCT
fnp-3528	664	3	h.	h.	PROPN
fnp-3528	664	4	;	;	PUNCT
fnp-3528	664	5	callaghan	callaghan	PROPN
fnp-3528	664	6	,	,	PUNCT
fnp-3528	664	7	d.	d.	PROPN
fnp-3528	664	8	;	;	PUNCT
fnp-3528	664	9	jones	jones	PROPN
fnp-3528	664	10	,	,	PUNCT
fnp-3528	664	11	a.	a.	PROPN
fnp-3528	664	12	;	;	PUNCT
fnp-3528	664	13	bai	bai	PROPN
fnp-3528	664	14	,	,	PUNCT
fnp-3528	664	15	j.	j.	PROPN
fnp-3528	664	16	;	;	PUNCT
fnp-3528	664	17	rasquinha	rasquinha	PROPN
fnp-3528	664	18	,	,	PUNCT
fnp-3528	664	19	i.	i.	PROPN
fnp-3528	664	20	;	;	PUNCT
fnp-3528	664	21	smith	smith	PROPN
fnp-3528	664	22	,	,	PUNCT
fnp-3528	664	23	c.	c.	PROPN
fnp-3528	664	24	;	;	PUNCT
fnp-3528	664	25	pei	pei	PROPN
fnp-3528	664	26	,	,	PUNCT
fnp-3528	664	27	k.	k.	PROPN
fnp-3528	664	28	;	;	PUNCT
fnp-3528	664	29	walker	walker	PROPN
fnp-3528	664	30	,	,	PUNCT
fnp-3528	664	31	d.	d.	PROPN
fnp-3528	664	32	;	;	PUNCT
fnp-3528	664	33	lue	lue	PROPN
fnp-3528	664	34	,	,	PUNCT
fnp-3528	664	35	l.	l.	PROPN
fnp-3528	664	36	f.	f.	PROPN
fnp-3528	664	37	;	;	PUNCT
fnp-3528	664	38	stanimirovic	stanimirovic	PROPN
fnp-3528	664	39	,	,	PUNCT
fnp-3528	664	40	d.	d.	PROPN
fnp-3528	664	41	;	;	PUNCT
fnp-3528	664	42	zhang	zhang	PROPN
fnp-3528	664	43	,	,	PUNCT
fnp-3528	664	44	w.	w.	PROPN
fnp-3528	664	45	abcg2	abcg2	PROPN
fnp-3528	664	46	is	be	AUX
fnp-3528	664	47	upregulated	upregulate	VERB
fnp-3528	664	48	in	in	ADP
fnp-3528	664	49	alzheimer	alzheimer	PROPN
fnp-3528	664	50	's	's	PART
fnp-3528	664	51	brain	brain	NOUN
fnp-3528	664	52	with	with	ADP
fnp-3528	664	53	cerebral	cerebral	ADJ
fnp-3528	664	54	amyloid	amyloid	NOUN
fnp-3528	664	55	angiopathy	angiopathy	NOUN
fnp-3528	664	56	and	and	CCONJ
fnp-3528	664	57	may	may	AUX
fnp-3528	664	58	act	act	VERB
fnp-3528	664	59	as	as	ADP
fnp-3528	664	60	a	a	DET
fnp-3528	664	61	gatekeeper	gatekeeper	NOUN
fnp-3528	664	62	at	at	ADP
fnp-3528	664	63	the	the	DET
fnp-3528	664	64	blood	blood	NOUN
fnp-3528	664	65	-	-	PUNCT
fnp-3528	664	66	brain	brain	NOUN
fnp-3528	664	67	barrier	barrier	NOUN
fnp-3528	664	68	for	for	ADP
fnp-3528	664	69	abeta(1	abeta(1	NOUN
fnp-3528	664	70	-	-	PUNCT
fnp-3528	664	71	40	40	NUM
fnp-3528	664	72	)	)	PUNCT
fnp-3528	664	73	peptides	peptide	NOUN
fnp-3528	664	74	.	.	PUNCT
fnp-3528	665	1	j	j	PROPN
fnp-3528	665	2	neurosci	neurosci	PROPN
fnp-3528	665	3	2009	2009	NUM
fnp-3528	665	4	,	,	PUNCT
fnp-3528	665	5	29	29	NUM
fnp-3528	665	6	,	,	PUNCT
fnp-3528	665	7	5463	5463	NUM
fnp-3528	665	8	-	-	SYM
fnp-3528	665	9	75	75	NUM
fnp-3528	665	10	.	.	PUNCT
fnp-3528	666	1	holmes	holmes	PROPN
fnp-3528	666	2	,	,	PUNCT
fnp-3528	666	3	c.	c.	PROPN
fnp-3528	666	4	;	;	PUNCT
fnp-3528	666	5	boche	boche	PROPN
fnp-3528	666	6	,	,	PUNCT
fnp-3528	666	7	d.	d.	PROPN
fnp-3528	666	8	;	;	PUNCT
fnp-3528	666	9	wilkinson	wilkinson	PROPN
fnp-3528	666	10	,	,	PUNCT
fnp-3528	666	11	d.	d.	PROPN
fnp-3528	666	12	;	;	PUNCT
fnp-3528	666	13	yadegarfar	yadegarfar	PROPN
fnp-3528	666	14	,	,	PUNCT
fnp-3528	666	15	g.	g.	PROPN
fnp-3528	666	16	;	;	PUNCT
fnp-3528	666	17	hopkins	hopkins	PROPN
fnp-3528	666	18	,	,	PUNCT
fnp-3528	666	19	v.	v.	PROPN
fnp-3528	666	20	;	;	PUNCT
fnp-3528	666	21	bayer	bayer	PROPN
fnp-3528	666	22	,	,	PUNCT
fnp-3528	666	23	a.	a.	PROPN
fnp-3528	666	24	;	;	PUNCT
fnp-3528	666	25	jones	jones	PROPN
fnp-3528	666	26	,	,	PUNCT
fnp-3528	666	27	r.	r.	PROPN
fnp-3528	666	28	w.	w.	PROPN
fnp-3528	666	29	;	;	PUNCT
fnp-3528	666	30	bullock	bullock	PROPN
fnp-3528	666	31	,	,	PUNCT
fnp-3528	666	32	r.	r.	PROPN
fnp-3528	666	33	;	;	PUNCT
fnp-3528	666	34	love	love	PROPN
fnp-3528	666	35	,	,	PUNCT
fnp-3528	666	36	s.	s.	PROPN
fnp-3528	666	37	;	;	PUNCT
fnp-3528	666	38	neal	neal	PROPN
fnp-3528	666	39	,	,	PUNCT
fnp-3528	666	40	j.	j.	PROPN
fnp-3528	666	41	w.	w.	PROPN
fnp-3528	666	42	;	;	PUNCT
fnp-3528	666	43	zotova	zotova	PROPN
fnp-3528	666	44	,	,	PUNCT
fnp-3528	666	45	e.	e.	PROPN
fnp-3528	666	46	;	;	PUNCT
fnp-3528	666	47	nicoll	nicoll	PROPN
fnp-3528	666	48	,	,	PUNCT
fnp-3528	666	49	j.	j.	PROPN
fnp-3528	666	50	a.	a.	PROPN
fnp-3528	666	51	long	long	ADJ
fnp-3528	666	52	-	-	PUNCT
fnp-3528	666	53	term	term	NOUN
fnp-3528	666	54	effects	effect	NOUN
fnp-3528	666	55	of	of	ADP
fnp-3528	666	56	abeta42	abeta42	NOUN
fnp-3528	666	57	immunisation	immunisation	NOUN
fnp-3528	666	58	in	in	ADP
fnp-3528	666	59	alzheimer	alzheimer	PROPN
fnp-3528	666	60	's	's	PART
fnp-3528	666	61	disease	disease	NOUN
fnp-3528	666	62	:	:	PUNCT
fnp-3528	666	63	follow	follow	VERB
fnp-3528	666	64	-	-	PUNCT
fnp-3528	666	65	up	up	NOUN
fnp-3528	666	66	of	of	ADP
fnp-3528	666	67	a	a	DET
fnp-3528	666	68	randomised	randomise	VERB
fnp-3528	666	69	,	,	PUNCT
fnp-3528	666	70	placebo	placebo	NOUN
fnp-3528	666	71	-	-	PUNCT
fnp-3528	666	72	controlled	control	VERB
fnp-3528	666	73	phase	phase	NOUN
fnp-3528	666	74	i	i	PRON
fnp-3528	666	75	trial	trial	NOUN
fnp-3528	666	76	.	.	PUNCT
fnp-3528	667	1	lancet	lancet	PROPN
fnp-3528	667	2	2008	2008	NUM
fnp-3528	667	3	,	,	PUNCT
fnp-3528	667	4	372	372	NUM
fnp-3528	667	5	,	,	PUNCT
fnp-3528	667	6	216	216	NUM
fnp-3528	667	7	-	-	SYM
fnp-3528	667	8	23	23	NUM
fnp-3528	667	9	.	.	PUNCT
fnp-3528	668	1	pahnke	pahnke	PROPN
fnp-3528	668	2	,	,	PUNCT
fnp-3528	668	3	j.	j.	PROPN
fnp-3528	668	4	;	;	PUNCT
fnp-3528	668	5	walker	walker	PROPN
fnp-3528	668	6	,	,	PUNCT
fnp-3528	668	7	l.	l.	PROPN
fnp-3528	668	8	c.	c.	PROPN
fnp-3528	668	9	;	;	PUNCT
fnp-3528	668	10	scheffler	scheffler	NOUN
fnp-3528	668	11	,	,	PUNCT
fnp-3528	668	12	k.	k.	PROPN
fnp-3528	668	13	;	;	PUNCT
fnp-3528	668	14	krohn	krohn	PROPN
fnp-3528	668	15	,	,	PUNCT
fnp-3528	668	16	m.	m.	PROPN
fnp-3528	668	17	alzheimer	alzheimer	PROPN
fnp-3528	668	18	's	's	PART
fnp-3528	668	19	disease	disease	NOUN
fnp-3528	668	20	and	and	CCONJ
fnp-3528	668	21	blood	blood	NOUN
fnp-3528	668	22	-	-	PUNCT
fnp-3528	668	23	brain	brain	NOUN
fnp-3528	668	24	barrier	barrier	NOUN
fnp-3528	668	25	function	function	NOUN
fnp-3528	668	26	-	-	PUNCT
fnp-3528	668	27	why	why	SCONJ
fnp-3528	668	28	have	have	AUX
fnp-3528	668	29	anti	anti	ADJ
fnp-3528	668	30	-	-	ADJ
fnp-3528	668	31	beta	beta	ADJ
fnp-3528	668	32	-	-	PUNCT
fnp-3528	668	33	amyloid	amyloid	NOUN
fnp-3528	668	34	therapies	therapy	NOUN
fnp-3528	668	35	failed	fail	VERB
fnp-3528	668	36	to	to	PART
fnp-3528	668	37	prevent	prevent	VERB
fnp-3528	668	38	dementia	dementia	NOUN
fnp-3528	668	39	progression	progression	NOUN
fnp-3528	668	40	?	?	PUNCT
fnp-3528	669	1	neurosci	neurosci	PROPN
fnp-3528	669	2	biobehav	biobehav	PROPN
fnp-3528	669	3	rev	rev	VERB
fnp-3528	669	4	2009	2009	NUM
fnp-3528	669	5	,	,	PUNCT
fnp-3528	669	6	33	33	NUM
fnp-3528	669	7	,	,	PUNCT
fnp-3528	669	8	1099	1099	NUM
fnp-3528	669	9	-	-	SYM
fnp-3528	669	10	108	108	NUM
fnp-3528	669	11	.	.	PUNCT
fnp-3528	670	1	pahnke	pahnke	PROPN
fnp-3528	670	2	,	,	PUNCT
fnp-3528	670	3	j.	j.	PROPN
fnp-3528	670	4	;	;	PUNCT
fnp-3528	670	5	wolkenhauer	wolkenhauer	PROPN
fnp-3528	670	6	,	,	PUNCT
fnp-3528	670	7	o.	o.	PROPN
fnp-3528	670	8	;	;	PUNCT
fnp-3528	670	9	krohn	krohn	PROPN
fnp-3528	670	10	,	,	PUNCT
fnp-3528	670	11	m.	m.	PROPN
fnp-3528	670	12	;	;	PUNCT
fnp-3528	670	13	walker	walker	PROPN
fnp-3528	670	14	,	,	PUNCT
fnp-3528	670	15	l.	l.	PROPN
fnp-3528	670	16	c.	c.	PROPN
fnp-3528	670	17	clinico	clinico	PROPN
fnp-3528	670	18	-	-	PUNCT
fnp-3528	670	19	pathologic	pathologic	ADJ
fnp-3528	670	20	function	function	NOUN
fnp-3528	670	21	of	of	ADP
fnp-3528	670	22	cerebral	cerebral	ADJ
fnp-3528	670	23	abc	abc	PROPN
fnp-3528	670	24	transporters	transporter	NOUN
fnp-3528	670	25	implications	implication	NOUN
fnp-3528	670	26	for	for	ADP
fnp-3528	670	27	the	the	DET
fnp-3528	670	28	pathogenesis	pathogenesis	NOUN
fnp-3528	670	29	of	of	ADP
fnp-3528	670	30	alzheimer	alzheimer	PROPN
fnp-3528	670	31	's	's	PART
fnp-3528	670	32	disease	disease	NOUN
fnp-3528	670	33	.	.	PUNCT
fnp-3528	671	1	curr	curr	PROPN
fnp-3528	671	2	alzheimer	alzheimer	PROPN
fnp-3528	671	3	res	res	PROPN
fnp-3528	671	4	2008	2008	NUM
fnp-3528	671	5	,	,	PUNCT
fnp-3528	671	6	5	5	NUM
fnp-3528	671	7	,	,	PUNCT
fnp-3528	671	8	396	396	NUM
fnp-3528	671	9	-	-	SYM
fnp-3528	671	10	405	405	NUM
fnp-3528	671	11	.	.	PUNCT
fnp-3528	672	1	walker	walker	PROPN
fnp-3528	672	2	,	,	PUNCT
fnp-3528	672	3	l.	l.	PROPN
fnp-3528	672	4	c.	c.	PROPN
fnp-3528	672	5	abeta	abeta	PROPN
fnp-3528	672	6	plaques	plaque	NOUN
fnp-3528	672	7	.	.	PUNCT
fnp-3528	673	1	free	free	ADJ
fnp-3528	673	2	neuropathol	neuropathol	NOUN
fnp-3528	673	3	2020	2020	NUM
fnp-3528	673	4	,	,	PUNCT
fnp-3528	673	5	1	1	NUM
fnp-3528	673	6	,	,	PUNCT
fnp-3528	673	7	31	31	NUM
fnp-3528	673	8	.	.	PUNCT
fnp-3528	674	1	behl	behl	PROPN
fnp-3528	674	2	,	,	PUNCT
fnp-3528	674	3	t.	t.	PROPN
fnp-3528	674	4	;	;	PUNCT
fnp-3528	674	5	kaur	kaur	PROPN
fnp-3528	674	6	,	,	PUNCT
fnp-3528	674	7	i.	i.	PROPN
fnp-3528	674	8	;	;	PUNCT
fnp-3528	674	9	sehgal	sehgal	PROPN
fnp-3528	674	10	,	,	PUNCT
fnp-3528	674	11	a.	a.	PROPN
fnp-3528	674	12	;	;	PUNCT
fnp-3528	674	13	kumar	kumar	PROPN
fnp-3528	674	14	,	,	PUNCT
fnp-3528	674	15	a.	a.	NOUN
fnp-3528	674	16	;	;	PUNCT
fnp-3528	674	17	uddin	uddin	PROPN
fnp-3528	674	18	,	,	PUNCT
fnp-3528	674	19	m.	m.	NOUN
fnp-3528	674	20	s.	s.	PROPN
fnp-3528	674	21	;	;	PUNCT
fnp-3528	674	22	bungau	bungau	NOUN
fnp-3528	674	23	,	,	PUNCT
fnp-3528	674	24	s.	s.	PROPN
fnp-3528	674	25	the	the	DET
fnp-3528	674	26	interplay	interplay	NOUN
fnp-3528	674	27	of	of	ADP
fnp-3528	674	28	abc	abc	PROPN
fnp-3528	674	29	transporters	transporter	NOUN
fnp-3528	674	30	in	in	ADP
fnp-3528	674	31	abeta	abeta	NOUN
fnp-3528	674	32	translocation	translocation	NOUN
fnp-3528	674	33	and	and	CCONJ
fnp-3528	674	34	cholesterol	cholesterol	NOUN
fnp-3528	674	35	metabolism	metabolism	NOUN
fnp-3528	674	36	:	:	PUNCT
fnp-3528	674	37	implicating	implicate	VERB
fnp-3528	674	38	their	their	PRON
fnp-3528	674	39	roles	role	NOUN
fnp-3528	674	40	in	in	ADP
fnp-3528	674	41	alzheimer	alzheimer	PROPN
fnp-3528	674	42	's	's	PART
fnp-3528	674	43	disease	disease	NOUN
fnp-3528	674	44	.	.	PUNCT
fnp-3528	675	1	mol	mol	ADP
fnp-3528	675	2	neurobiol	neurobiol	PROPN
fnp-3528	675	3	2021	2021	NUM
fnp-3528	675	4	,	,	PUNCT
fnp-3528	675	5	58	58	NUM
fnp-3528	675	6	,	,	PUNCT
fnp-3528	675	7	1564	1564	NUM
fnp-3528	675	8	-	-	SYM
fnp-3528	675	9	82	82	NUM
fnp-3528	675	10	.	.	PUNCT
fnp-3528	676	1	koldamova	koldamova	PROPN
fnp-3528	676	2	,	,	PUNCT
fnp-3528	676	3	r.	r.	PROPN
fnp-3528	676	4	;	;	PUNCT
fnp-3528	676	5	fitz	fitz	PROPN
fnp-3528	676	6	,	,	PUNCT
fnp-3528	676	7	n.	n.	PROPN
fnp-3528	676	8	f.	f.	PROPN
fnp-3528	676	9	;	;	PUNCT
fnp-3528	676	10	lefterov	lefterov	PROPN
fnp-3528	676	11	,	,	PUNCT
fnp-3528	676	12	i.	i.	PROPN
fnp-3528	676	13	atp	atp	PROPN
fnp-3528	676	14	-	-	PUNCT
fnp-3528	676	15	binding	bind	VERB
fnp-3528	676	16	cassette	cassette	NOUN
fnp-3528	676	17	transporter	transporter	NOUN
fnp-3528	676	18	a1	a1	NOUN
fnp-3528	676	19	:	:	PUNCT
fnp-3528	676	20	from	from	ADP
fnp-3528	676	21	metabolism	metabolism	NOUN
fnp-3528	676	22	to	to	ADP
fnp-3528	676	23	neurodegeneration	neurodegeneration	NOUN
fnp-3528	676	24	.	.	PUNCT
fnp-3528	677	1	neurobiol	neurobiol	PROPN
fnp-3528	677	2	dis	dis	PROPN
fnp-3528	677	3	2014	2014	NUM
fnp-3528	677	4	,	,	PUNCT
fnp-3528	677	5	72	72	NUM
fnp-3528	677	6	pt	pt	NOUN
fnp-3528	677	7	a	a	PRON
fnp-3528	677	8	,	,	PUNCT
fnp-3528	677	9	13	13	NUM
fnp-3528	677	10	-	-	SYM
fnp-3528	677	11	21	21	NUM
fnp-3528	677	12	.	.	PUNCT
fnp-3528	678	1	lyssenko	lyssenko	PROPN
fnp-3528	678	2	,	,	PUNCT
fnp-3528	678	3	n.	n.	PROPN
fnp-3528	678	4	n.	n.	PROPN
fnp-3528	678	5	;	;	PUNCT
fnp-3528	678	6	praticò	praticò	NOUN
fnp-3528	678	7	,	,	PUNCT
fnp-3528	678	8	d.	d.	PROPN
fnp-3528	678	9	abca7	abca7	PROPN
fnp-3528	678	10	and	and	CCONJ
fnp-3528	678	11	the	the	DET
fnp-3528	678	12	altered	alter	VERB
fnp-3528	678	13	lipidostasis	lipidostasis	NOUN
fnp-3528	678	14	hypothesis	hypothesis	NOUN
fnp-3528	678	15	of	of	ADP
fnp-3528	678	16	alzheimer	alzheimer	PROPN
fnp-3528	678	17	's	's	PART
fnp-3528	678	18	disease	disease	NOUN
fnp-3528	678	19	.	.	PUNCT
fnp-3528	679	1	alzheimers	alzheimers	PROPN
fnp-3528	679	2	dement	dement	PROPN
fnp-3528	679	3	2020	2020	NUM
fnp-3528	679	4	,	,	PUNCT
fnp-3528	679	5	17	17	NUM
fnp-3528	679	6	,	,	PUNCT
fnp-3528	679	7	164	164	NUM
fnp-3528	679	8	-	-	SYM
fnp-3528	679	9	174	174	NUM
fnp-3528	679	10	.	.	PUNCT
fnp-3528	680	1	abe	abe	PROPN
fnp-3528	680	2	-	-	PUNCT
fnp-3528	680	3	dohmae	dohmae	PROPN
fnp-3528	680	4	,	,	PUNCT
fnp-3528	680	5	s.	s.	PROPN
fnp-3528	680	6	;	;	PUNCT
fnp-3528	680	7	yokoyama	yokoyama	PROPN
fnp-3528	680	8	,	,	PUNCT
fnp-3528	681	1	s.	s.	PROPN
fnp-3528	681	2	abca7	abca7	PROPN
fnp-3528	681	3	links	link	VERB
fnp-3528	681	4	sterol	sterol	VERB
fnp-3528	681	5	metabolism	metabolism	NOUN
fnp-3528	681	6	to	to	ADP
fnp-3528	681	7	the	the	DET
fnp-3528	681	8	host	host	NOUN
fnp-3528	681	9	defense	defense	NOUN
fnp-3528	681	10	system	system	NOUN
fnp-3528	681	11	:	:	PUNCT
fnp-3528	681	12	molecular	molecular	ADJ
fnp-3528	681	13	background	background	NOUN
fnp-3528	681	14	for	for	ADP
fnp-3528	681	15	potential	potential	ADJ
fnp-3528	681	16	management	management	NOUN
fnp-3528	681	17	measure	measure	NOUN
fnp-3528	681	18	of	of	ADP
fnp-3528	681	19	alzheimer	alzheimer	PROPN
fnp-3528	681	20	's	's	PART
fnp-3528	681	21	disease	disease	NOUN
fnp-3528	681	22	.	.	PUNCT
fnp-3528	682	1	gene	gene	NOUN
fnp-3528	682	2	2021	2021	NUM
fnp-3528	682	3	,	,	PUNCT
fnp-3528	682	4	768	768	NUM
fnp-3528	682	5	,	,	PUNCT
fnp-3528	682	6	145316	145316	NUM
fnp-3528	682	7	.	.	PUNCT
fnp-3528	683	1	aikawa	aikawa	PROPN
fnp-3528	683	2	,	,	PUNCT
fnp-3528	683	3	t.	t.	PROPN
fnp-3528	683	4	;	;	PUNCT
fnp-3528	683	5	holm	holm	PROPN
fnp-3528	683	6	,	,	PUNCT
fnp-3528	683	7	m.	m.	NOUN
fnp-3528	683	8	l.	l.	PROPN
fnp-3528	683	9	;	;	PUNCT
fnp-3528	683	10	kanekiyo	kanekiyo	PROPN
fnp-3528	683	11	,	,	PUNCT
fnp-3528	683	12	t.	t.	PROPN
fnp-3528	683	13	abca7	abca7	PROPN
fnp-3528	683	14	and	and	CCONJ
fnp-3528	683	15	pathogenic	pathogenic	ADJ
fnp-3528	683	16	pathways	pathway	NOUN
fnp-3528	683	17	of	of	ADP
fnp-3528	683	18	alzheimer	alzheimer	PROPN
fnp-3528	683	19	's	's	PART
fnp-3528	683	20	disease	disease	NOUN
fnp-3528	683	21	.	.	PUNCT
fnp-3528	684	1	brain	brain	NOUN
fnp-3528	684	2	sci	sci	PROPN
fnp-3528	684	3	2018	2018	NUM
fnp-3528	684	4	,	,	PUNCT
fnp-3528	684	5	8	8	NUM
fnp-3528	684	6	,	,	PUNCT
fnp-3528	684	7	27	27	NUM
fnp-3528	684	8	.	.	PUNCT
fnp-3528	685	1	li	li	PROPN
fnp-3528	685	2	,	,	PUNCT
fnp-3528	685	3	h.	h.	PROPN
fnp-3528	685	4	;	;	PUNCT
fnp-3528	685	5	karl	karl	PROPN
fnp-3528	685	6	,	,	PUNCT
fnp-3528	685	7	t.	t.	PROPN
fnp-3528	685	8	;	;	PUNCT
fnp-3528	685	9	garner	garner	PROPN
fnp-3528	685	10	,	,	PUNCT
fnp-3528	685	11	b.	b.	PROPN
fnp-3528	685	12	understanding	understand	VERB
fnp-3528	685	13	the	the	DET
fnp-3528	685	14	function	function	NOUN
fnp-3528	685	15	of	of	ADP
fnp-3528	685	16	abca7	abca7	PROPN
fnp-3528	685	17	in	in	ADP
fnp-3528	685	18	alzheimer	alzheimer	PROPN
fnp-3528	685	19	's	's	PART
fnp-3528	685	20	disease	disease	NOUN
fnp-3528	685	21	.	.	PUNCT
fnp-3528	686	1	biochem	biochem	PROPN
fnp-3528	686	2	soc	soc	VERB
fnp-3528	686	3	trans	trans	PROPN
fnp-3528	686	4	2015	2015	NUM
fnp-3528	686	5	,	,	PUNCT
fnp-3528	686	6	43	43	NUM
fnp-3528	686	7	,	,	PUNCT
fnp-3528	686	8	920	920	NUM
fnp-3528	686	9	-	-	SYM
fnp-3528	686	10	3	3	NUM
fnp-3528	686	11	.	.	PUNCT
fnp-3528	687	1	andrews	andrews	PROPN
fnp-3528	687	2	,	,	PUNCT
fnp-3528	687	3	s.	s.	PROPN
fnp-3528	687	4	j.	j.	PROPN
fnp-3528	687	5	;	;	PUNCT
fnp-3528	687	6	fulton	fulton	PROPN
fnp-3528	687	7	-	-	PUNCT
fnp-3528	687	8	howard	howard	PROPN
fnp-3528	687	9	,	,	PUNCT
fnp-3528	687	10	b.	b.	PROPN
fnp-3528	687	11	;	;	PUNCT
fnp-3528	687	12	goate	goate	NOUN
fnp-3528	687	13	,	,	PUNCT
fnp-3528	687	14	a.	a.	NOUN
fnp-3528	687	15	protective	protective	ADJ
fnp-3528	687	16	variants	variant	NOUN
fnp-3528	687	17	in	in	ADP
fnp-3528	687	18	alzheimer	alzheimer	PROPN
fnp-3528	687	19	's	's	PART
fnp-3528	687	20	disease	disease	NOUN
fnp-3528	687	21	.	.	PUNCT
fnp-3528	688	1	curr	curr	PROPN
fnp-3528	688	2	genet	genet	PROPN
fnp-3528	688	3	med	med	PROPN
fnp-3528	688	4	rep	rep	PROPN
fnp-3528	688	5	2019	2019	NUM
fnp-3528	688	6	,	,	PUNCT
fnp-3528	688	7	7	7	NUM
fnp-3528	688	8	,	,	PUNCT
fnp-3528	688	9	1	1	NUM
fnp-3528	688	10	-	-	SYM
fnp-3528	688	11	12	12	NUM
fnp-3528	688	12	.	.	PUNCT
fnp-3528	689	1	teresa	teresa	PROPN
fnp-3528	689	2	,	,	PUNCT
fnp-3528	689	3	j.	j.	PROPN
fnp-3528	689	4	c.	c.	PROPN
fnp-3528	689	5	;	;	PUNCT
fnp-3528	689	6	fernado	fernado	PROPN
fnp-3528	689	7	,	,	PUNCT
fnp-3528	689	8	c.	c.	NOUN
fnp-3528	689	9	;	;	PUNCT
fnp-3528	689	10	nancy	nancy	PROPN
fnp-3528	689	11	,	,	PUNCT
fnp-3528	689	12	m.	m.	PROPN
fnp-3528	689	13	r.	r.	PROPN
fnp-3528	689	14	;	;	PUNCT
fnp-3528	689	15	gilberto	gilberto	PROPN
fnp-3528	689	16	,	,	PUNCT
fnp-3528	689	17	v.	v.	PROPN
fnp-3528	689	18	a.	a.	PROPN
fnp-3528	689	19	;	;	PUNCT
fnp-3528	689	20	alberto	alberto	PROPN
fnp-3528	689	21	,	,	PUNCT
fnp-3528	689	22	c.	c.	PROPN
fnp-3528	689	23	r.	r.	PROPN
fnp-3528	689	24	;	;	PUNCT
fnp-3528	689	25	roberto	roberto	PROPN
fnp-3528	689	26	,	,	PUNCT
fnp-3528	689	27	r.	r.	PROPN
fnp-3528	689	28	r.	r.	PROPN
fnp-3528	689	29	association	association	PROPN
fnp-3528	689	30	of	of	ADP
fnp-3528	689	31	genetic	genetic	ADJ
fnp-3528	689	32	variants	variant	NOUN
fnp-3528	689	33	of	of	ADP
fnp-3528	689	34	abca1	abca1	NOUN
fnp-3528	689	35	with	with	ADP
fnp-3528	689	36	susceptibility	susceptibility	NOUN
fnp-3528	689	37	to	to	ADP
fnp-3528	689	38	dementia	dementia	NOUN
fnp-3528	689	39	:	:	PUNCT
fnp-3528	689	40	(	(	PUNCT
fnp-3528	689	41	sadem	sadem	ADJ
fnp-3528	689	42	study	study	NOUN
fnp-3528	689	43	)	)	PUNCT
fnp-3528	689	44	.	.	PUNCT
fnp-3528	690	1	metab	metab	ADJ
fnp-3528	690	2	brain	brain	NOUN
fnp-3528	690	3	dis	dis	PROPN
fnp-3528	690	4	2020	2020	NUM
fnp-3528	690	5	,	,	PUNCT
fnp-3528	690	6	35	35	NUM
fnp-3528	690	7	,	,	PUNCT
fnp-3528	690	8	915	915	NUM
fnp-3528	690	9	-	-	SYM
fnp-3528	690	10	22	22	NUM
fnp-3528	690	11	.	.	PUNCT
fnp-3528	691	1	jiang	jiang	PROPN
fnp-3528	691	2	,	,	PUNCT
fnp-3528	691	3	s.	s.	PROPN
fnp-3528	691	4	;	;	PUNCT
fnp-3528	691	5	zhang	zhang	PROPN
fnp-3528	691	6	,	,	PUNCT
fnp-3528	691	7	c.	c.	PROPN
fnp-3528	691	8	y.	y.	PROPN
fnp-3528	691	9	;	;	PUNCT
fnp-3528	691	10	tang	tang	PROPN
fnp-3528	691	11	,	,	PUNCT
fnp-3528	691	12	l.	l.	PROPN
fnp-3528	691	13	;	;	PUNCT
fnp-3528	691	14	zhao	zhao	PROPN
fnp-3528	691	15	,	,	PUNCT
fnp-3528	691	16	l.	l.	PROPN
fnp-3528	691	17	x.	x.	PROPN
fnp-3528	691	18	;	;	PUNCT
fnp-3528	691	19	chen	chen	PROPN
fnp-3528	691	20	,	,	PUNCT
fnp-3528	691	21	h.	h.	PROPN
fnp-3528	691	22	z.	z.	PROPN
fnp-3528	691	23	;	;	PUNCT
fnp-3528	691	24	qiu	qiu	PROPN
fnp-3528	691	25	,	,	PUNCT
fnp-3528	691	26	y.	y.	NOUN
fnp-3528	691	27	integrated	integrate	VERB
fnp-3528	691	28	genomic	genomic	NOUN
fnp-3528	691	29	analysis	analysis	NOUN
fnp-3528	691	30	revealed	reveal	VERB
fnp-3528	691	31	associated	associated	ADJ
fnp-3528	691	32	genes	gene	NOUN
fnp-3528	691	33	for	for	ADP
fnp-3528	691	34	alzheimer	alzheimer	PROPN
fnp-3528	691	35	's	's	PART
fnp-3528	691	36	disease	disease	NOUN
fnp-3528	691	37	in	in	ADP
fnp-3528	691	38	apoe4	apoe4	PROPN
fnp-3528	691	39	non	non	NOUN
fnp-3528	691	40	-	-	NOUN
fnp-3528	691	41	carriers	carrier	NOUN
fnp-3528	691	42	.	.	PUNCT
fnp-3528	692	1	curr	curr	PROPN
fnp-3528	692	2	alzheimer	alzheimer	PROPN
fnp-3528	692	3	res	res	PROPN
fnp-3528	692	4	2019	2019	NUM
fnp-3528	692	5	,	,	PUNCT
fnp-3528	692	6	16	16	NUM
fnp-3528	692	7	,	,	PUNCT
fnp-3528	692	8	753	753	NUM
fnp-3528	692	9	-	-	SYM
fnp-3528	692	10	63	63	NUM
fnp-3528	692	11	.	.	PUNCT
fnp-3528	693	1	chen	chen	PROPN
fnp-3528	693	2	,	,	PUNCT
fnp-3528	693	3	q.	q.	PROPN
fnp-3528	693	4	;	;	PUNCT
fnp-3528	693	5	liang	liang	PROPN
fnp-3528	693	6	,	,	PUNCT
fnp-3528	693	7	b.	b.	PROPN
fnp-3528	693	8	;	;	PUNCT
fnp-3528	693	9	wang	wang	PROPN
fnp-3528	693	10	,	,	PUNCT
fnp-3528	693	11	z.	z.	PROPN
fnp-3528	693	12	;	;	PUNCT
fnp-3528	693	13	cheng	cheng	PROPN
fnp-3528	693	14	,	,	PUNCT
fnp-3528	693	15	x.	x.	PROPN
fnp-3528	693	16	;	;	PUNCT
fnp-3528	693	17	huang	huang	PROPN
fnp-3528	693	18	,	,	PUNCT
fnp-3528	693	19	y.	y.	PROPN
fnp-3528	693	20	;	;	PUNCT
fnp-3528	693	21	liu	liu	PROPN
fnp-3528	693	22	,	,	PUNCT
fnp-3528	693	23	y.	y.	PROPN
fnp-3528	693	24	;	;	PUNCT
fnp-3528	693	25	huang	huang	PROPN
fnp-3528	693	26	,	,	PUNCT
fnp-3528	693	27	z.	z.	PROPN
fnp-3528	693	28	influence	influence	NOUN
fnp-3528	693	29	of	of	ADP
fnp-3528	693	30	four	four	NUM
fnp-3528	693	31	polymorphisms	polymorphism	NOUN
fnp-3528	693	32	in	in	ADP
fnp-3528	693	33	abca1	abca1	NOUN
fnp-3528	693	34	and	and	CCONJ
fnp-3528	693	35	ptgs2	ptgs2	PROPN
fnp-3528	693	36	genes	gene	NOUN
fnp-3528	693	37	on	on	ADP
fnp-3528	693	38	risk	risk	NOUN
fnp-3528	693	39	of	of	ADP
fnp-3528	693	40	alzheimer	alzheimer	PROPN
fnp-3528	693	41	's	's	PART
fnp-3528	693	42	disease	disease	NOUN
fnp-3528	693	43	:	:	PUNCT
fnp-3528	693	44	a	a	DET
fnp-3528	693	45	meta	meta	ADJ
fnp-3528	693	46	-	-	PUNCT
fnp-3528	693	47	analysis	analysis	NOUN
fnp-3528	693	48	.	.	PUNCT
fnp-3528	694	1	neurol	neurol	NOUN
fnp-3528	694	2	sci	sci	PROPN
fnp-3528	694	3	2016	2016	NUM
fnp-3528	694	4	,	,	PUNCT
fnp-3528	694	5	37	37	NUM
fnp-3528	694	6	,	,	PUNCT
fnp-3528	694	7	1209	1209	NUM
fnp-3528	694	8	-	-	SYM
fnp-3528	694	9	20	20	NUM
fnp-3528	694	10	.	.	PUNCT
fnp-3528	695	1	piaceri	piaceri	PROPN
fnp-3528	695	2	,	,	PUNCT
fnp-3528	695	3	i.	i.	PROPN
fnp-3528	695	4	;	;	PUNCT
fnp-3528	695	5	nacmias	nacmias	PROPN
fnp-3528	695	6	,	,	PUNCT
fnp-3528	695	7	b.	b.	PROPN
fnp-3528	695	8	;	;	PUNCT
fnp-3528	695	9	sorbi	sorbi	PROPN
fnp-3528	695	10	,	,	PUNCT
fnp-3528	695	11	s.	s.	PROPN
fnp-3528	695	12	genetics	genetics	PROPN
fnp-3528	695	13	of	of	ADP
fnp-3528	695	14	familial	familial	ADJ
fnp-3528	695	15	and	and	CCONJ
fnp-3528	695	16	sporadic	sporadic	ADJ
fnp-3528	695	17	alzheimer	alzheimer	PROPN
fnp-3528	695	18	's	's	PART
fnp-3528	695	19	disease	disease	NOUN
fnp-3528	695	20	.	.	PUNCT
fnp-3528	696	1	front	front	ADJ
fnp-3528	696	2	biosci	biosci	PROPN
fnp-3528	696	3	(	(	PUNCT
fnp-3528	696	4	elite	elite	ADJ
fnp-3528	696	5	ed	ed	NOUN
fnp-3528	696	6	)	)	PUNCT
fnp-3528	696	7	2013	2013	NUM
fnp-3528	696	8	,	,	PUNCT
fnp-3528	696	9	5	5	NUM
fnp-3528	696	10	,	,	PUNCT
fnp-3528	696	11	167	167	NUM
fnp-3528	696	12	-	-	SYM
fnp-3528	696	13	77	77	NUM
fnp-3528	696	14	.	.	PUNCT
fnp-3528	697	1	agarwal	agarwal	PROPN
fnp-3528	697	2	,	,	PUNCT
fnp-3528	697	3	m.	m.	NOUN
fnp-3528	697	4	;	;	PUNCT
fnp-3528	697	5	khan	khan	PROPN
fnp-3528	697	6	,	,	PUNCT
fnp-3528	697	7	s.	s.	PROPN
fnp-3528	697	8	plasma	plasma	PROPN
fnp-3528	697	9	lipids	lipid	VERB
fnp-3528	697	10	as	as	ADP
fnp-3528	697	11	biomarkers	biomarker	NOUN
fnp-3528	697	12	for	for	ADP
fnp-3528	697	13	alzheimer	alzheimer	PROPN
fnp-3528	697	14	's	's	PART
fnp-3528	697	15	disease	disease	NOUN
fnp-3528	697	16	:	:	PUNCT
fnp-3528	697	17	a	a	DET
fnp-3528	697	18	systematic	systematic	ADJ
fnp-3528	697	19	review	review	NOUN
fnp-3528	697	20	.	.	PUNCT
fnp-3528	698	1	cureus	cureus	PROPN
fnp-3528	698	2	2020	2020	NUM
fnp-3528	698	3	,	,	PUNCT
fnp-3528	698	4	12	12	NUM
fnp-3528	698	5	,	,	PUNCT
fnp-3528	698	6	e12008	e12008	NOUN
fnp-3528	698	7	.	.	PUNCT
fnp-3528	699	1	picard	picard	PROPN
fnp-3528	699	2	,	,	PUNCT
fnp-3528	699	3	c.	c.	PROPN
fnp-3528	699	4	;	;	PUNCT
fnp-3528	699	5	julien	julien	PROPN
fnp-3528	699	6	,	,	PUNCT
fnp-3528	699	7	c.	c.	PROPN
fnp-3528	699	8	;	;	PUNCT
fnp-3528	699	9	frappier	frappier	PROPN
fnp-3528	699	10	,	,	PUNCT
fnp-3528	699	11	j.	j.	PROPN
fnp-3528	699	12	;	;	PUNCT
fnp-3528	699	13	miron	miron	PROPN
fnp-3528	699	14	,	,	PUNCT
fnp-3528	699	15	j.	j.	PROPN
fnp-3528	699	16	;	;	PUNCT
fnp-3528	699	17	théroux	théroux	PROPN
fnp-3528	699	18	,	,	PUNCT
fnp-3528	699	19	l.	l.	PROPN
fnp-3528	699	20	;	;	PUNCT
fnp-3528	699	21	dea	dea	PROPN
fnp-3528	699	22	,	,	PUNCT
fnp-3528	699	23	d.	d.	PROPN
fnp-3528	699	24	;	;	PUNCT
fnp-3528	699	25	breitner	breitner	NOUN
fnp-3528	699	26	,	,	PUNCT
fnp-3528	699	27	j.	j.	PROPN
fnp-3528	699	28	c.	c.	PROPN
fnp-3528	699	29	s.	s.	PROPN
fnp-3528	699	30	;	;	PUNCT
fnp-3528	699	31	poirier	poirier	PROPN
fnp-3528	699	32	,	,	PUNCT
fnp-3528	699	33	j.	j.	PROPN
fnp-3528	699	34	alterations	alteration	NOUN
fnp-3528	699	35	in	in	ADP
fnp-3528	699	36	cholesterol	cholesterol	NOUN
fnp-3528	699	37	metabolism	metabolism	NOUN
fnp-3528	699	38	-	-	PUNCT
fnp-3528	699	39	related	relate	VERB
fnp-3528	699	40	genes	gene	NOUN
fnp-3528	699	41	in	in	ADP
fnp-3528	699	42	sporadic	sporadic	ADJ
fnp-3528	699	43	alzheimer	alzheimer	PROPN
fnp-3528	699	44	's	's	PART
fnp-3528	699	45	disease	disease	NOUN
fnp-3528	699	46	.	.	PUNCT
fnp-3528	700	1	neurobiol	neurobiol	PROPN
fnp-3528	700	2	aging	age	VERB
fnp-3528	700	3	2018	2018	NUM
fnp-3528	700	4	,	,	PUNCT
fnp-3528	700	5	66	66	NUM
fnp-3528	700	6	,	,	PUNCT
fnp-3528	700	7	180.e1	180.e1	NUM
fnp-3528	700	8	-	-	SYM
fnp-3528	700	9	180.e9	180.e9	NUM
fnp-3528	700	10	.	.	PUNCT
fnp-3528	701	1	beel	beel	PROPN
fnp-3528	701	2	,	,	PUNCT
fnp-3528	701	3	a.	a.	PROPN
fnp-3528	701	4	j.	j.	PROPN
fnp-3528	701	5	;	;	PUNCT
fnp-3528	701	6	sakakura	sakakura	PROPN
fnp-3528	701	7	,	,	PUNCT
fnp-3528	701	8	m.	m.	NOUN
fnp-3528	701	9	;	;	PUNCT
fnp-3528	701	10	barrett	barrett	PROPN
fnp-3528	701	11	,	,	PUNCT
fnp-3528	701	12	p.	p.	PROPN
fnp-3528	701	13	j.	j.	PROPN
fnp-3528	701	14	;	;	PUNCT
fnp-3528	701	15	sanders	sanders	PROPN
fnp-3528	701	16	,	,	PUNCT
fnp-3528	701	17	c.	c.	PROPN
fnp-3528	701	18	r.	r.	PROPN
fnp-3528	701	19	direct	direct	PROPN
fnp-3528	701	20	binding	bind	VERB
fnp-3528	701	21	of	of	ADP
fnp-3528	701	22	cholesterol	cholesterol	NOUN
fnp-3528	701	23	to	to	ADP
fnp-3528	701	24	the	the	DET
fnp-3528	701	25	amyloid	amyloid	NOUN
fnp-3528	701	26	precursor	precursor	NOUN
fnp-3528	701	27	protein	protein	NOUN
fnp-3528	701	28	:	:	PUNCT
fnp-3528	701	29	an	an	DET
fnp-3528	701	30	important	important	ADJ
fnp-3528	701	31	interaction	interaction	NOUN
fnp-3528	701	32	in	in	ADP
fnp-3528	701	33	lipid	lipid	NOUN
fnp-3528	701	34	-	-	PUNCT
fnp-3528	701	35	alzheimer	alzheimer	NOUN
fnp-3528	701	36	's	's	PART
fnp-3528	701	37	disease	disease	NOUN
fnp-3528	701	38	relationships	relationship	NOUN
fnp-3528	701	39	?	?	PUNCT
fnp-3528	702	1	biochim	biochim	PROPN
fnp-3528	702	2	biophys	biophy	NOUN
fnp-3528	702	3	acta	acta	PROPN
fnp-3528	702	4	2010	2010	NUM
fnp-3528	702	5	,	,	PUNCT
fnp-3528	702	6	1801	1801	NUM
fnp-3528	702	7	,	,	PUNCT
fnp-3528	702	8	975	975	NUM
fnp-3528	702	9	-	-	SYM
fnp-3528	702	10	82	82	NUM
fnp-3528	702	11	.	.	PUNCT
fnp-3528	702	12	shobab	shobab	PROPN
fnp-3528	702	13	,	,	PUNCT
fnp-3528	702	14	l.	l.	PROPN
fnp-3528	702	15	a.	a.	PROPN
fnp-3528	702	16	;	;	PUNCT
fnp-3528	702	17	hsiung	hsiung	PROPN
fnp-3528	702	18	,	,	PUNCT
fnp-3528	702	19	g.	g.	PROPN
fnp-3528	702	20	y.	y.	PROPN
fnp-3528	702	21	;	;	PUNCT
fnp-3528	702	22	feldman	feldman	PROPN
fnp-3528	702	23	,	,	PUNCT
fnp-3528	702	24	h.	h.	PROPN
fnp-3528	702	25	h.	h.	PROPN
fnp-3528	702	26	cholesterol	cholesterol	PROPN
fnp-3528	702	27	in	in	ADP
fnp-3528	702	28	alzheimer	alzheimer	PROPN
fnp-3528	702	29	's	's	PART
fnp-3528	702	30	disease	disease	NOUN
fnp-3528	702	31	.	.	PUNCT
fnp-3528	703	1	lancet	lancet	PROPN
fnp-3528	703	2	neurol	neurol	PROPN
fnp-3528	703	3	2005	2005	NUM
fnp-3528	703	4	,	,	PUNCT
fnp-3528	703	5	4	4	NUM
fnp-3528	703	6	,	,	PUNCT
fnp-3528	703	7	841	841	NUM
fnp-3528	703	8	-	-	SYM
fnp-3528	703	9	52	52	NUM
fnp-3528	703	10	.	.	PUNCT
fnp-3528	704	1	sviridov	sviridov	PROPN
fnp-3528	704	2	,	,	PUNCT
fnp-3528	704	3	d.	d.	PROPN
fnp-3528	704	4	;	;	PUNCT
fnp-3528	704	5	mukhamedova	mukhamedova	PROPN
fnp-3528	704	6	,	,	PUNCT
fnp-3528	704	7	n.	n.	PROPN
fnp-3528	704	8	;	;	PUNCT
fnp-3528	704	9	miller	miller	PROPN
fnp-3528	704	10	,	,	PUNCT
fnp-3528	704	11	y.	y.	PROPN
fnp-3528	704	12	i.	i.	PROPN
fnp-3528	704	13	lipid	lipid	PROPN
fnp-3528	704	14	rafts	raft	NOUN
fnp-3528	704	15	as	as	ADP
fnp-3528	704	16	a	a	DET
fnp-3528	704	17	therapeutic	therapeutic	ADJ
fnp-3528	704	18	target	target	NOUN
fnp-3528	704	19	.	.	PUNCT
fnp-3528	705	1	j	j	PROPN
fnp-3528	705	2	lipid	lipid	PROPN
fnp-3528	705	3	res	re	NOUN
fnp-3528	705	4	2020	2020	NUM
fnp-3528	705	5	,	,	PUNCT
fnp-3528	705	6	61	61	NUM
fnp-3528	705	7	,	,	PUNCT
fnp-3528	705	8	687	687	NUM
fnp-3528	705	9	-	-	SYM
fnp-3528	705	10	695	695	NUM
fnp-3528	705	11	.	.	PUNCT
fnp-3528	706	1	satoh	satoh	NOUN
fnp-3528	706	2	,	,	PUNCT
fnp-3528	706	3	k.	k.	PROPN
fnp-3528	706	4	;	;	PUNCT
fnp-3528	706	5	abe	abe	PROPN
fnp-3528	706	6	-	-	PUNCT
fnp-3528	706	7	dohmae	dohmae	PROPN
fnp-3528	706	8	,	,	PUNCT
fnp-3528	706	9	s.	s.	PROPN
fnp-3528	706	10	;	;	PUNCT
fnp-3528	706	11	yokoyama	yokoyama	PROPN
fnp-3528	706	12	,	,	PUNCT
fnp-3528	706	13	s.	s.	PROPN
fnp-3528	706	14	;	;	PUNCT
fnp-3528	706	15	st	st	PROPN
fnp-3528	706	16	george	george	PROPN
fnp-3528	706	17	-	-	PUNCT
fnp-3528	706	18	hyslop	hyslop	PROPN
fnp-3528	706	19	,	,	PUNCT
fnp-3528	706	20	p.	p.	NOUN
fnp-3528	706	21	;	;	PUNCT
fnp-3528	706	22	fraser	fraser	PROPN
fnp-3528	706	23	,	,	PUNCT
fnp-3528	706	24	p.	p.	PROPN
fnp-3528	706	25	e.	e.	PROPN
fnp-3528	706	26	atp	atp	PROPN
fnp-3528	706	27	-	-	PUNCT
fnp-3528	706	28	binding	bind	VERB
fnp-3528	706	29	cassette	cassette	NOUN
fnp-3528	706	30	transporter	transporter	NOUN
fnp-3528	706	31	a7	a7	PROPN
fnp-3528	706	32	(	(	PUNCT
fnp-3528	706	33	abca7	abca7	NOUN
fnp-3528	706	34	)	)	PUNCT
fnp-3528	706	35	loss	loss	NOUN
fnp-3528	706	36	of	of	ADP
fnp-3528	706	37	function	function	NOUN
fnp-3528	706	38	alters	alter	VERB
fnp-3528	706	39	alzheimer	alzheimer	PROPN
fnp-3528	706	40	amyloid	amyloid	NOUN
fnp-3528	706	41	processing	processing	NOUN
fnp-3528	706	42	.	.	PUNCT
fnp-3528	707	1	j	j	PROPN
fnp-3528	707	2	biol	biol	PROPN
fnp-3528	707	3	chem	chem	NOUN
fnp-3528	707	4	2015	2015	NUM
fnp-3528	707	5	,	,	PUNCT
fnp-3528	707	6	290	290	NUM
fnp-3528	707	7	,	,	PUNCT
fnp-3528	707	8	24152	24152	NUM
fnp-3528	707	9	-	-	SYM
fnp-3528	707	10	65	65	NUM
fnp-3528	707	11	.	.	PUNCT
fnp-3528	708	1	zhao	zhao	PROPN
fnp-3528	708	2	,	,	PUNCT
fnp-3528	708	3	q.	q.	PROPN
fnp-3528	708	4	f.	f.	PROPN
fnp-3528	708	5	;	;	PUNCT
fnp-3528	708	6	yu	yu	PROPN
fnp-3528	708	7	,	,	PUNCT
fnp-3528	708	8	j.	j.	PROPN
fnp-3528	708	9	t.	t.	PROPN
fnp-3528	708	10	;	;	PUNCT
fnp-3528	708	11	tan	tan	PROPN
fnp-3528	708	12	,	,	PUNCT
fnp-3528	708	13	m.	m.	NOUN
fnp-3528	708	14	s.	s.	PROPN
fnp-3528	708	15	;	;	PUNCT
fnp-3528	708	16	tan	tan	PROPN
fnp-3528	708	17	,	,	PUNCT
fnp-3528	708	18	l.	l.	PROPN
fnp-3528	708	19	abca7	abca7	PROPN
fnp-3528	708	20	in	in	ADP
fnp-3528	708	21	alzheimer	alzheimer	PROPN
fnp-3528	708	22	's	's	PART
fnp-3528	708	23	disease	disease	NOUN
fnp-3528	708	24	.	.	PUNCT
fnp-3528	709	1	mol	mol	ADP
fnp-3528	709	2	neurobiol	neurobiol	PROPN
fnp-3528	709	3	2015	2015	NUM
fnp-3528	709	4	,	,	PUNCT
fnp-3528	709	5	51	51	NUM
fnp-3528	709	6	,	,	PUNCT
fnp-3528	709	7	1008	1008	NUM
fnp-3528	709	8	-	-	SYM
fnp-3528	709	9	16	16	NUM
fnp-3528	709	10	.	.	PUNCT
fnp-3528	710	1	chan	chan	PROPN
fnp-3528	710	2	,	,	PUNCT
fnp-3528	710	3	s.	s.	PROPN
fnp-3528	710	4	l.	l.	PROPN
fnp-3528	710	5	;	;	PUNCT
fnp-3528	710	6	kim	kim	PROPN
fnp-3528	710	7	,	,	PUNCT
fnp-3528	710	8	w.	w.	PROPN
fnp-3528	710	9	s.	s.	PROPN
fnp-3528	710	10	;	;	PUNCT
fnp-3528	710	11	kwok	kwok	PROPN
fnp-3528	710	12	,	,	PUNCT
fnp-3528	710	13	j.	j.	PROPN
fnp-3528	710	14	b.	b.	PROPN
fnp-3528	710	15	;	;	PUNCT
fnp-3528	710	16	hill	hill	PROPN
fnp-3528	710	17	,	,	PUNCT
fnp-3528	710	18	a.	a.	PROPN
fnp-3528	710	19	f.	f.	PROPN
fnp-3528	710	20	;	;	PUNCT
fnp-3528	710	21	cappai	cappai	PROPN
fnp-3528	710	22	,	,	PUNCT
fnp-3528	710	23	r.	r.	PROPN
fnp-3528	710	24	;	;	PUNCT
fnp-3528	710	25	rye	rye	PROPN
fnp-3528	710	26	,	,	PUNCT
fnp-3528	710	27	k.	k.	PROPN
fnp-3528	710	28	a.	a.	PROPN
fnp-3528	710	29	;	;	PUNCT
fnp-3528	710	30	garner	garner	PROPN
fnp-3528	710	31	,	,	PUNCT
fnp-3528	710	32	b.	b.	PROPN
fnp-3528	710	33	atp	atp	PROPN
fnp-3528	710	34	-	-	PUNCT
fnp-3528	710	35	binding	bind	VERB
fnp-3528	710	36	cassette	cassette	NOUN
fnp-3528	710	37	transporter	transporter	NOUN
fnp-3528	710	38	a7	a7	PROPN
fnp-3528	710	39	regulates	regulate	VERB
fnp-3528	710	40	processing	processing	NOUN
fnp-3528	710	41	of	of	ADP
fnp-3528	710	42	amyloid	amyloid	NOUN
fnp-3528	710	43	precursor	precursor	NOUN
fnp-3528	710	44	protein	protein	NOUN
fnp-3528	710	45	in	in	ADP
fnp-3528	710	46	vitro	vitro	VERB
fnp-3528	710	47	.	.	PUNCT
fnp-3528	711	1	j	j	PROPN
fnp-3528	711	2	neurochem	neurochem	PROPN
fnp-3528	711	3	2008	2008	NUM
fnp-3528	711	4	,	,	PUNCT
fnp-3528	711	5	106	106	NUM
fnp-3528	711	6	,	,	PUNCT
fnp-3528	711	7	793	793	NUM
fnp-3528	711	8	-	-	SYM
fnp-3528	711	9	804	804	NUM
fnp-3528	711	10	.	.	PUNCT
fnp-3528	712	1	sun	sun	PROPN
fnp-3528	712	2	,	,	PUNCT
fnp-3528	712	3	y.	y.	PROPN
fnp-3528	712	4	;	;	PUNCT
fnp-3528	712	5	yao	yao	PROPN
fnp-3528	712	6	,	,	PUNCT
fnp-3528	712	7	j.	j.	PROPN
fnp-3528	712	8	;	;	PUNCT
fnp-3528	712	9	kim	kim	PROPN
fnp-3528	712	10	,	,	PUNCT
fnp-3528	712	11	t.	t.	PROPN
fnp-3528	712	12	w.	w.	PROPN
fnp-3528	712	13	;	;	PUNCT
fnp-3528	712	14	tall	tall	ADJ
fnp-3528	712	15	,	,	PUNCT
fnp-3528	712	16	a.	a.	PROPN
fnp-3528	712	17	r.	r.	PROPN
fnp-3528	712	18	expression	expression	NOUN
fnp-3528	712	19	of	of	ADP
fnp-3528	712	20	liver	liver	NOUN
fnp-3528	712	21	x	x	SYM
fnp-3528	712	22	receptor	receptor	NOUN
fnp-3528	712	23	target	target	NOUN
fnp-3528	712	24	genes	gene	NOUN
fnp-3528	712	25	decreases	decrease	VERB
fnp-3528	712	26	cellular	cellular	ADJ
fnp-3528	712	27	amyloid	amyloid	NOUN
fnp-3528	712	28	beta	beta	NOUN
fnp-3528	712	29	peptide	peptide	NOUN
fnp-3528	712	30	secretion	secretion	NOUN
fnp-3528	712	31	.	.	PUNCT
fnp-3528	713	1	j	j	PROPN
fnp-3528	713	2	biol	biol	PROPN
fnp-3528	713	3	chem	chem	NOUN
fnp-3528	713	4	2003	2003	NUM
fnp-3528	713	5	,	,	PUNCT
fnp-3528	713	6	278	278	NUM
fnp-3528	713	7	,	,	PUNCT
fnp-3528	713	8	27688	27688	NUM
fnp-3528	713	9	-	-	SYM
fnp-3528	713	10	94	94	NUM
fnp-3528	713	11	.	.	PUNCT
fnp-3528	714	1	koldamova	koldamova	PROPN
fnp-3528	714	2	,	,	PUNCT
fnp-3528	714	3	r.	r.	PROPN
fnp-3528	714	4	p.	p.	PROPN
fnp-3528	714	5	;	;	PUNCT
fnp-3528	714	6	lefterov	lefterov	PROPN
fnp-3528	714	7	,	,	PUNCT
fnp-3528	714	8	i.	i.	NOUN
fnp-3528	714	9	m.	m.	NOUN
fnp-3528	714	10	;	;	PUNCT
fnp-3528	714	11	ikonomovic	ikonomovic	ADJ
fnp-3528	714	12	,	,	PUNCT
fnp-3528	714	13	m.	m.	NOUN
fnp-3528	714	14	d.	d.	PROPN
fnp-3528	714	15	;	;	PUNCT
fnp-3528	714	16	skoko	skoko	PROPN
fnp-3528	714	17	,	,	PUNCT
fnp-3528	714	18	j.	j.	PROPN
fnp-3528	714	19	;	;	PUNCT
fnp-3528	714	20	lefterov	lefterov	PROPN
fnp-3528	714	21	,	,	PUNCT
fnp-3528	714	22	p.	p.	NOUN
fnp-3528	714	23	i.	i.	NOUN
fnp-3528	714	24	;	;	PUNCT
fnp-3528	714	25	isanski	isanski	NOUN
fnp-3528	714	26	,	,	PUNCT
fnp-3528	714	27	b.	b.	PROPN
fnp-3528	714	28	a.	a.	PROPN
fnp-3528	714	29	;	;	PUNCT
fnp-3528	714	30	dekosky	dekosky	PROPN
fnp-3528	714	31	,	,	PUNCT
fnp-3528	714	32	s.	s.	PROPN
fnp-3528	714	33	t.	t.	PROPN
fnp-3528	714	34	;	;	PUNCT
fnp-3528	714	35	lazo	lazo	PROPN
fnp-3528	714	36	,	,	PUNCT
fnp-3528	714	37	j.	j.	PROPN
fnp-3528	714	38	s.	s.	PROPN
fnp-3528	714	39	22r	22r	PROPN
fnp-3528	714	40	-	-	PUNCT
fnp-3528	714	41	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	714	42	and	and	CCONJ
fnp-3528	714	43	9	9	NUM
fnp-3528	714	44	-	-	PUNCT
fnp-3528	714	45	cis	cis	NOUN
fnp-3528	714	46	-	-	PUNCT
fnp-3528	714	47	retinoic	retinoic	NOUN
fnp-3528	714	48	acid	acid	NOUN
fnp-3528	714	49	induce	induce	VERB
fnp-3528	714	50	atp	atp	NOUN
fnp-3528	714	51	-	-	PUNCT
fnp-3528	714	52	binding	bind	VERB
fnp-3528	714	53	cassette	cassette	NOUN
fnp-3528	714	54	transporter	transporter	NOUN
fnp-3528	714	55	a1	a1	NOUN
fnp-3528	714	56	expression	expression	NOUN
fnp-3528	714	57	and	and	CCONJ
fnp-3528	714	58	cholesterol	cholesterol	NOUN
fnp-3528	714	59	efflux	efflux	VERB
fnp-3528	714	60	in	in	ADP
fnp-3528	714	61	brain	brain	NOUN
fnp-3528	714	62	cells	cell	NOUN
fnp-3528	714	63	and	and	CCONJ
fnp-3528	714	64	decrease	decrease	VERB
fnp-3528	714	65	amyloid	amyloid	NOUN
fnp-3528	714	66	beta	beta	NOUN
fnp-3528	714	67	secretion	secretion	NOUN
fnp-3528	714	68	.	.	PUNCT
fnp-3528	715	1	j	j	PROPN
fnp-3528	715	2	biol	biol	PROPN
fnp-3528	715	3	chem	chem	NOUN
fnp-3528	715	4	2003	2003	NUM
fnp-3528	715	5	,	,	PUNCT
fnp-3528	715	6	278	278	NUM
fnp-3528	715	7	,	,	PUNCT
fnp-3528	715	8	13244	13244	NUM
fnp-3528	715	9	-	-	SYM
fnp-3528	715	10	56	56	NUM
fnp-3528	715	11	.	.	PUNCT
fnp-3528	716	1	fu	fu	PROPN
fnp-3528	716	2	,	,	PUNCT
fnp-3528	716	3	y.	y.	PROPN
fnp-3528	716	4	;	;	PUNCT
fnp-3528	716	5	hsiao	hsiao	PROPN
fnp-3528	716	6	,	,	PUNCT
fnp-3528	716	7	j.	j.	PROPN
fnp-3528	716	8	h.	h.	PROPN
fnp-3528	716	9	;	;	PUNCT
fnp-3528	716	10	paxinos	paxino	NOUN
fnp-3528	716	11	,	,	PUNCT
fnp-3528	716	12	g.	g.	PROPN
fnp-3528	716	13	;	;	PUNCT
fnp-3528	716	14	halliday	halliday	PROPN
fnp-3528	716	15	,	,	PUNCT
fnp-3528	716	16	g.	g.	PROPN
fnp-3528	716	17	m.	m.	PROPN
fnp-3528	716	18	;	;	PUNCT
fnp-3528	716	19	kim	kim	PROPN
fnp-3528	716	20	,	,	PUNCT
fnp-3528	716	21	w.	w.	PROPN
fnp-3528	716	22	s.	s.	PROPN
fnp-3528	716	23	abca7	abca7	PROPN
fnp-3528	716	24	mediates	mediate	VERB
fnp-3528	716	25	phagocytic	phagocytic	ADJ
fnp-3528	716	26	clearance	clearance	NOUN
fnp-3528	716	27	of	of	ADP
fnp-3528	716	28	amyloid	amyloid	NOUN
fnp-3528	716	29	-	-	PUNCT
fnp-3528	716	30	beta	beta	NOUN
fnp-3528	716	31	in	in	ADP
fnp-3528	716	32	the	the	DET
fnp-3528	716	33	brain	brain	NOUN
fnp-3528	716	34	.	.	PUNCT
fnp-3528	717	1	j	j	PROPN
fnp-3528	717	2	alzheimers	alzheimers	PROPN
fnp-3528	717	3	dis	dis	PROPN
fnp-3528	717	4	2016	2016	NUM
fnp-3528	717	5	,	,	PUNCT
fnp-3528	717	6	54	54	NUM
fnp-3528	717	7	,	,	PUNCT
fnp-3528	717	8	569	569	NUM
fnp-3528	717	9	-	-	SYM
fnp-3528	717	10	84	84	NUM
fnp-3528	717	11	.	.	PUNCT
fnp-3528	718	1	kim	kim	PROPN
fnp-3528	718	2	,	,	PUNCT
fnp-3528	718	3	w.	w.	PROPN
fnp-3528	718	4	s.	s.	PROPN
fnp-3528	718	5	;	;	PUNCT
fnp-3528	718	6	li	li	PROPN
fnp-3528	718	7	,	,	PUNCT
fnp-3528	718	8	h.	h.	PROPN
fnp-3528	718	9	;	;	PUNCT
fnp-3528	718	10	ruberu	ruberu	PROPN
fnp-3528	718	11	,	,	PUNCT
fnp-3528	718	12	k.	k.	PROPN
fnp-3528	718	13	;	;	PUNCT
fnp-3528	719	1	chan	chan	PROPN
fnp-3528	719	2	,	,	PUNCT
fnp-3528	719	3	s.	s.	PROPN
fnp-3528	719	4	;	;	PUNCT
fnp-3528	719	5	elliott	elliott	PROPN
fnp-3528	719	6	,	,	PUNCT
fnp-3528	719	7	d.	d.	PROPN
fnp-3528	719	8	a.	a.	PROPN
fnp-3528	719	9	;	;	PUNCT
fnp-3528	719	10	low	low	ADJ
fnp-3528	719	11	,	,	PUNCT
fnp-3528	719	12	j.	j.	PROPN
fnp-3528	719	13	k.	k.	PROPN
fnp-3528	719	14	;	;	PUNCT
fnp-3528	719	15	cheng	cheng	PROPN
fnp-3528	719	16	,	,	PUNCT
fnp-3528	719	17	d.	d.	PROPN
fnp-3528	719	18	;	;	PUNCT
fnp-3528	719	19	karl	karl	PROPN
fnp-3528	719	20	,	,	PUNCT
fnp-3528	719	21	t.	t.	PROPN
fnp-3528	719	22	;	;	PUNCT
fnp-3528	719	23	garner	garner	PROPN
fnp-3528	719	24	,	,	PUNCT
fnp-3528	719	25	b.	b.	PROPN
fnp-3528	719	26	deletion	deletion	NOUN
fnp-3528	719	27	of	of	ADP
fnp-3528	719	28	abca7	abca7	PROPN
fnp-3528	719	29	increases	increase	VERB
fnp-3528	719	30	cerebral	cerebral	ADJ
fnp-3528	719	31	amyloid	amyloid	NOUN
fnp-3528	719	32	-	-	PUNCT
fnp-3528	719	33	beta	beta	NOUN
fnp-3528	719	34	accumulation	accumulation	NOUN
fnp-3528	719	35	in	in	ADP
fnp-3528	719	36	the	the	DET
fnp-3528	719	37	j20	j20	PROPN
fnp-3528	719	38	mouse	mouse	PROPN
fnp-3528	719	39	model	model	NOUN
fnp-3528	719	40	of	of	ADP
fnp-3528	719	41	alzheimer	alzheimer	PROPN
fnp-3528	719	42	's	's	PART
fnp-3528	719	43	disease	disease	NOUN
fnp-3528	719	44	.	.	PUNCT
fnp-3528	720	1	j	j	PROPN
fnp-3528	720	2	neurosci	neurosci	PROPN
fnp-3528	720	3	2013	2013	NUM
fnp-3528	720	4	,	,	PUNCT
fnp-3528	720	5	33	33	NUM
fnp-3528	720	6	,	,	PUNCT
fnp-3528	720	7	4387	4387	NUM
fnp-3528	720	8	-	-	SYM
fnp-3528	720	9	94	94	NUM
fnp-3528	720	10	.	.	PUNCT
fnp-3528	721	1	koldamova	koldamova	PROPN
fnp-3528	721	2	,	,	PUNCT
fnp-3528	721	3	r.	r.	PROPN
fnp-3528	721	4	;	;	PUNCT
fnp-3528	721	5	fitz	fitz	PROPN
fnp-3528	721	6	,	,	PUNCT
fnp-3528	721	7	n.	n.	PROPN
fnp-3528	721	8	f.	f.	PROPN
fnp-3528	721	9	;	;	PUNCT
fnp-3528	721	10	lefterov	lefterov	PROPN
fnp-3528	721	11	,	,	PUNCT
fnp-3528	721	12	i.	i.	NOUN
fnp-3528	721	13	the	the	DET
fnp-3528	721	14	role	role	NOUN
fnp-3528	721	15	of	of	ADP
fnp-3528	721	16	atp	atp	NOUN
fnp-3528	721	17	-	-	PUNCT
fnp-3528	721	18	binding	bind	VERB
fnp-3528	721	19	cassette	cassette	NOUN
fnp-3528	721	20	transporter	transporter	NOUN
fnp-3528	721	21	a1	a1	NOUN
fnp-3528	721	22	in	in	ADP
fnp-3528	721	23	alzheimer	alzheimer	PROPN
fnp-3528	721	24	's	's	PART
fnp-3528	721	25	disease	disease	NOUN
fnp-3528	721	26	and	and	CCONJ
fnp-3528	721	27	neurodegeneration	neurodegeneration	NOUN
fnp-3528	721	28	.	.	PUNCT
fnp-3528	722	1	biochim	biochim	PROPN
fnp-3528	722	2	biophys	biophy	NOUN
fnp-3528	722	3	acta	acta	PROPN
fnp-3528	722	4	2010	2010	NUM
fnp-3528	722	5	,	,	PUNCT
fnp-3528	722	6	1801	1801	NUM
fnp-3528	722	7	,	,	PUNCT
fnp-3528	722	8	824	824	NUM
fnp-3528	722	9	-	-	SYM
fnp-3528	722	10	30	30	NUM
fnp-3528	722	11	.	.	PUNCT
fnp-3528	723	1	jiang	jiang	PROPN
fnp-3528	723	2	,	,	PUNCT
fnp-3528	723	3	q.	q.	PROPN
fnp-3528	723	4	;	;	PUNCT
fnp-3528	723	5	lee	lee	PROPN
fnp-3528	723	6	,	,	PUNCT
fnp-3528	723	7	c.	c.	PROPN
fnp-3528	723	8	y.	y.	PROPN
fnp-3528	723	9	;	;	PUNCT
fnp-3528	723	10	mandrekar	mandrekar	PROPN
fnp-3528	723	11	,	,	PUNCT
fnp-3528	723	12	s.	s.	PROPN
fnp-3528	723	13	;	;	PUNCT
fnp-3528	723	14	wilkinson	wilkinson	PROPN
fnp-3528	723	15	,	,	PUNCT
fnp-3528	723	16	b.	b.	PROPN
fnp-3528	723	17	;	;	PUNCT
fnp-3528	723	18	cramer	cramer	PROPN
fnp-3528	723	19	,	,	PUNCT
fnp-3528	723	20	p.	p.	NOUN
fnp-3528	723	21	;	;	PUNCT
fnp-3528	723	22	zelcer	zelcer	NOUN
fnp-3528	723	23	,	,	PUNCT
fnp-3528	723	24	n.	n.	NOUN
fnp-3528	723	25	;	;	PUNCT
fnp-3528	723	26	mann	mann	PROPN
fnp-3528	723	27	,	,	PUNCT
fnp-3528	723	28	k.	k.	PROPN
fnp-3528	723	29	;	;	PUNCT
fnp-3528	723	30	lamb	lamb	PROPN
fnp-3528	723	31	,	,	PUNCT
fnp-3528	723	32	b.	b.	PROPN
fnp-3528	723	33	;	;	PUNCT
fnp-3528	723	34	willson	willson	PROPN
fnp-3528	723	35	,	,	PUNCT
fnp-3528	723	36	t.	t.	PROPN
fnp-3528	723	37	m.	m.	NOUN
fnp-3528	723	38	;	;	PUNCT
fnp-3528	723	39	collins	collins	PROPN
fnp-3528	723	40	,	,	PUNCT
fnp-3528	723	41	j.	j.	PROPN
fnp-3528	723	42	l.	l.	PROPN
fnp-3528	723	43	;	;	PUNCT
fnp-3528	723	44	richardson	richardson	PROPN
fnp-3528	723	45	,	,	PUNCT
fnp-3528	723	46	j.	j.	PROPN
fnp-3528	723	47	c.	c.	PROPN
fnp-3528	723	48	;	;	PUNCT
fnp-3528	723	49	smith	smith	PROPN
fnp-3528	723	50	,	,	PUNCT
fnp-3528	723	51	j.	j.	PROPN
fnp-3528	723	52	d.	d.	PROPN
fnp-3528	723	53	;	;	PUNCT
fnp-3528	723	54	comery	comery	NOUN
fnp-3528	723	55	,	,	PUNCT
fnp-3528	723	56	t.	t.	NOUN
fnp-3528	723	57	a.	a.	NOUN
fnp-3528	723	58	;	;	PUNCT
fnp-3528	723	59	riddell	riddell	PROPN
fnp-3528	723	60	,	,	PUNCT
fnp-3528	723	61	d.	d.	PROPN
fnp-3528	723	62	;	;	PUNCT
fnp-3528	723	63	holtzman	holtzman	PROPN
fnp-3528	723	64	,	,	PUNCT
fnp-3528	723	65	d.	d.	PROPN
fnp-3528	723	66	m.	m.	PROPN
fnp-3528	723	67	;	;	PUNCT
fnp-3528	723	68	tontonoz	tontonoz	PROPN
fnp-3528	723	69	,	,	PUNCT
fnp-3528	723	70	p.	p.	PROPN
fnp-3528	723	71	;	;	PUNCT
fnp-3528	723	72	landreth	landreth	PROPN
fnp-3528	723	73	,	,	PUNCT
fnp-3528	723	74	g.	g.	PROPN
fnp-3528	723	75	e.	e.	PROPN
fnp-3528	723	76	apoe	apoe	PROPN
fnp-3528	723	77	promotes	promote	VERB
fnp-3528	723	78	the	the	DET
fnp-3528	723	79	proteolytic	proteolytic	ADJ
fnp-3528	723	80	degradation	degradation	NOUN
fnp-3528	723	81	of	of	ADP
fnp-3528	723	82	abeta	abeta	PROPN
fnp-3528	723	83	.	.	PROPN
fnp-3528	723	84	neuron	neuron	PROPN
fnp-3528	723	85	2008	2008	NUM
fnp-3528	723	86	,	,	PUNCT
fnp-3528	723	87	58	58	NUM
fnp-3528	723	88	,	,	PUNCT
fnp-3528	723	89	681	681	NUM
fnp-3528	723	90	-	-	SYM
fnp-3528	723	91	93	93	NUM
fnp-3528	723	92	.	.	PUNCT
fnp-3528	724	1	wahrle	wahrle	NOUN
fnp-3528	724	2	,	,	PUNCT
fnp-3528	724	3	s.	s.	PROPN
fnp-3528	724	4	e.	e.	PROPN
fnp-3528	724	5	;	;	PUNCT
fnp-3528	724	6	jiang	jiang	PROPN
fnp-3528	724	7	,	,	PUNCT
fnp-3528	724	8	h.	h.	PROPN
fnp-3528	724	9	;	;	PUNCT
fnp-3528	724	10	parsadanian	parsadanian	ADJ
fnp-3528	724	11	,	,	PUNCT
fnp-3528	724	12	m.	m.	NOUN
fnp-3528	724	13	;	;	PUNCT
fnp-3528	724	14	kim	kim	PROPN
fnp-3528	724	15	,	,	PUNCT
fnp-3528	724	16	j.	j.	PROPN
fnp-3528	724	17	;	;	PUNCT
fnp-3528	724	18	li	li	PROPN
fnp-3528	724	19	,	,	PUNCT
fnp-3528	724	20	a.	a.	NOUN
fnp-3528	724	21	;	;	PUNCT
fnp-3528	724	22	knoten	knoten	PROPN
fnp-3528	724	23	,	,	PUNCT
fnp-3528	724	24	a.	a.	PROPN
fnp-3528	724	25	;	;	PUNCT
fnp-3528	724	26	jain	jain	PROPN
fnp-3528	724	27	,	,	PUNCT
fnp-3528	724	28	s.	s.	PROPN
fnp-3528	724	29	;	;	PUNCT
fnp-3528	724	30	hirsch	hirsch	PROPN
fnp-3528	724	31	-	-	PUNCT
fnp-3528	724	32	reinshagen	reinshagen	NOUN
fnp-3528	724	33	,	,	PUNCT
fnp-3528	724	34	v.	v.	PROPN
fnp-3528	724	35	;	;	PUNCT
fnp-3528	724	36	wellington	wellington	PROPN
fnp-3528	724	37	,	,	PUNCT
fnp-3528	724	38	c.	c.	PROPN
fnp-3528	724	39	l.	l.	PROPN
fnp-3528	724	40	;	;	PUNCT
fnp-3528	724	41	bales	bale	NOUN
fnp-3528	724	42	,	,	PUNCT
fnp-3528	724	43	k.	k.	PROPN
fnp-3528	724	44	r.	r.	PROPN
fnp-3528	724	45	;	;	PUNCT
fnp-3528	724	46	paul	paul	PROPN
fnp-3528	724	47	,	,	PUNCT
fnp-3528	724	48	s.	s.	PROPN
fnp-3528	724	49	m.	m.	PROPN
fnp-3528	724	50	;	;	PUNCT
fnp-3528	724	51	holtzman	holtzman	NOUN
fnp-3528	724	52	,	,	PUNCT
fnp-3528	724	53	d.	d.	PROPN
fnp-3528	724	54	m.	m.	PROPN
fnp-3528	724	55	overexpression	overexpression	NOUN
fnp-3528	724	56	of	of	ADP
fnp-3528	724	57	abca1	abca1	NOUN
fnp-3528	724	58	reduces	reduce	VERB
fnp-3528	724	59	amyloid	amyloid	NOUN
fnp-3528	724	60	deposition	deposition	NOUN
fnp-3528	724	61	in	in	ADP
fnp-3528	724	62	the	the	DET
fnp-3528	724	63	pdapp	pdapp	NOUN
fnp-3528	724	64	mouse	mouse	NOUN
fnp-3528	724	65	model	model	NOUN
fnp-3528	724	66	of	of	ADP
fnp-3528	724	67	alzheimer	alzheimer	PROPN
fnp-3528	724	68	disease	disease	PROPN
fnp-3528	724	69	.	.	PUNCT
fnp-3528	725	1	j	j	PROPN
fnp-3528	725	2	clin	clin	PROPN
fnp-3528	725	3	invest	invest	VERB
fnp-3528	725	4	2008	2008	NUM
fnp-3528	725	5	,	,	PUNCT
fnp-3528	725	6	118	118	NUM
fnp-3528	725	7	,	,	PUNCT
fnp-3528	725	8	671	671	NUM
fnp-3528	725	9	-	-	SYM
fnp-3528	725	10	82	82	NUM
fnp-3528	725	11	.	.	PUNCT
fnp-3528	726	1	saint	saint	NOUN
fnp-3528	726	2	-	-	PUNCT
fnp-3528	726	3	pol	pol	PROPN
fnp-3528	726	4	,	,	PUNCT
fnp-3528	726	5	j.	j.	PROPN
fnp-3528	726	6	;	;	PUNCT
fnp-3528	726	7	vandenhaute	vandenhaute	PROPN
fnp-3528	726	8	,	,	PUNCT
fnp-3528	726	9	e.	e.	PROPN
fnp-3528	726	10	;	;	PUNCT
fnp-3528	726	11	boucau	boucau	PROPN
fnp-3528	726	12	,	,	PUNCT
fnp-3528	726	13	m.	m.	PROPN
fnp-3528	726	14	c.	c.	PROPN
fnp-3528	726	15	;	;	PUNCT
fnp-3528	726	16	candela	candela	PROPN
fnp-3528	726	17	,	,	PUNCT
fnp-3528	726	18	p.	p.	NOUN
fnp-3528	726	19	;	;	PUNCT
fnp-3528	726	20	dehouck	dehouck	VERB
fnp-3528	726	21	,	,	PUNCT
fnp-3528	726	22	l.	l.	PROPN
fnp-3528	726	23	;	;	PUNCT
fnp-3528	726	24	cecchelli	cecchelli	PROPN
fnp-3528	726	25	,	,	PUNCT
fnp-3528	726	26	r.	r.	PROPN
fnp-3528	726	27	;	;	PUNCT
fnp-3528	726	28	dehouck	dehouck	VERB
fnp-3528	726	29	,	,	PUNCT
fnp-3528	726	30	m.	m.	NOUN
fnp-3528	726	31	p.	p.	NOUN
fnp-3528	726	32	;	;	PUNCT
fnp-3528	726	33	fenart	fenart	NOUN
fnp-3528	726	34	,	,	PUNCT
fnp-3528	726	35	l.	l.	PROPN
fnp-3528	726	36	;	;	PUNCT
fnp-3528	726	37	gosselet	gosselet	NOUN
fnp-3528	726	38	,	,	PUNCT
fnp-3528	726	39	f.	f.	PROPN
fnp-3528	726	40	brain	brain	PROPN
fnp-3528	726	41	pericytes	pericyte	NOUN
fnp-3528	726	42	abca1	abca1	NOUN
fnp-3528	726	43	expression	expression	NOUN
fnp-3528	726	44	mediates	mediate	VERB
fnp-3528	726	45	cholesterol	cholesterol	NOUN
fnp-3528	726	46	efflux	efflux	NOUN
fnp-3528	726	47	but	but	CCONJ
fnp-3528	726	48	not	not	PART
fnp-3528	726	49	cellular	cellular	ADJ
fnp-3528	726	50	amyloid	amyloid	NOUN
fnp-3528	726	51	-	-	PUNCT
fnp-3528	726	52	beta	beta	NOUN
fnp-3528	726	53	peptide	peptide	NOUN
fnp-3528	726	54	accumulation	accumulation	NOUN
fnp-3528	726	55	.	.	PUNCT
fnp-3528	727	1	j	j	PROPN
fnp-3528	727	2	alzheimers	alzheimers	PROPN
fnp-3528	727	3	dis	dis	PROPN
fnp-3528	727	4	2012	2012	NUM
fnp-3528	727	5	,	,	PUNCT
fnp-3528	727	6	30	30	NUM
fnp-3528	727	7	,	,	PUNCT
fnp-3528	727	8	489	489	NUM
fnp-3528	727	9	-	-	SYM
fnp-3528	727	10	503	503	NUM
fnp-3528	727	11	.	.	PUNCT
fnp-3528	728	1	akanuma	akanuma	PROPN
fnp-3528	728	2	,	,	PUNCT
fnp-3528	728	3	s.	s.	PROPN
fnp-3528	728	4	;	;	PUNCT
fnp-3528	728	5	ohtsuki	ohtsuki	PROPN
fnp-3528	728	6	,	,	PUNCT
fnp-3528	728	7	s.	s.	PROPN
fnp-3528	728	8	;	;	PUNCT
fnp-3528	728	9	doi	doi	PROPN
fnp-3528	728	10	,	,	PUNCT
fnp-3528	728	11	y.	y.	PROPN
fnp-3528	728	12	;	;	PUNCT
fnp-3528	728	13	tachikawa	tachikawa	PROPN
fnp-3528	728	14	,	,	PUNCT
fnp-3528	728	15	m.	m.	NOUN
fnp-3528	728	16	;	;	PUNCT
fnp-3528	728	17	ito	ito	PROPN
fnp-3528	728	18	,	,	PUNCT
fnp-3528	728	19	s.	s.	PROPN
fnp-3528	728	20	;	;	PUNCT
fnp-3528	728	21	hori	hori	PROPN
fnp-3528	728	22	,	,	PUNCT
fnp-3528	728	23	s.	s.	PROPN
fnp-3528	728	24	;	;	PUNCT
fnp-3528	728	25	asashima	asashima	PROPN
fnp-3528	728	26	,	,	PUNCT
fnp-3528	728	27	t.	t.	PROPN
fnp-3528	728	28	;	;	PUNCT
fnp-3528	728	29	hashimoto	hashimoto	NOUN
fnp-3528	728	30	,	,	PUNCT
fnp-3528	728	31	t.	t.	PROPN
fnp-3528	728	32	;	;	PUNCT
fnp-3528	728	33	yamada	yamada	PROPN
fnp-3528	728	34	,	,	PUNCT
fnp-3528	728	35	k.	k.	PROPN
fnp-3528	728	36	;	;	PUNCT
fnp-3528	728	37	ueda	ueda	PROPN
fnp-3528	728	38	,	,	PUNCT
fnp-3528	728	39	k.	k.	PROPN
fnp-3528	728	40	;	;	PUNCT
fnp-3528	728	41	iwatsubo	iwatsubo	ADJ
fnp-3528	728	42	,	,	PUNCT
fnp-3528	728	43	t.	t.	PROPN
fnp-3528	728	44	;	;	PUNCT
fnp-3528	728	45	terasaki	terasaki	PROPN
fnp-3528	728	46	,	,	PUNCT
fnp-3528	728	47	t.	t.	PROPN
fnp-3528	728	48	atp	atp	PROPN
fnp-3528	728	49	-	-	PUNCT
fnp-3528	728	50	binding	bind	VERB
fnp-3528	728	51	cassette	cassette	NOUN
fnp-3528	728	52	transporter	transporter	NOUN
fnp-3528	728	53	a1	a1	NOUN
fnp-3528	728	54	(	(	PUNCT
fnp-3528	728	55	abca1	abca1	NOUN
fnp-3528	728	56	)	)	PUNCT
fnp-3528	728	57	deficiency	deficiency	NOUN
fnp-3528	728	58	does	do	AUX
fnp-3528	728	59	not	not	PART
fnp-3528	728	60	attenuate	attenuate	VERB
fnp-3528	728	61	the	the	DET
fnp-3528	728	62	brain	brain	NOUN
fnp-3528	728	63	-	-	PUNCT
fnp-3528	728	64	to	to	ADP
fnp-3528	728	65	-	-	PUNCT
fnp-3528	728	66	blood	blood	NOUN
fnp-3528	728	67	efflux	efflux	NOUN
fnp-3528	728	68	transport	transport	NOUN
fnp-3528	728	69	of	of	ADP
fnp-3528	728	70	human	human	ADJ
fnp-3528	728	71	amyloid	amyloid	NOUN
fnp-3528	728	72	-	-	PUNCT
fnp-3528	728	73	beta	beta	NOUN
fnp-3528	728	74	peptide	peptide	NOUN
fnp-3528	728	75	(	(	PUNCT
fnp-3528	728	76	1	1	NUM
fnp-3528	728	77	-	-	SYM
fnp-3528	728	78	40	40	NUM
fnp-3528	728	79	)	)	PUNCT
fnp-3528	728	80	at	at	ADP
fnp-3528	728	81	the	the	DET
fnp-3528	728	82	blood	blood	NOUN
fnp-3528	728	83	-	-	PUNCT
fnp-3528	728	84	brain	brain	NOUN
fnp-3528	728	85	barrier	barrier	NOUN
fnp-3528	728	86	.	.	PUNCT
fnp-3528	729	1	neurochem	neurochem	PROPN
fnp-3528	729	2	int	int	PROPN
fnp-3528	729	3	2008	2008	NUM
fnp-3528	729	4	,	,	PUNCT
fnp-3528	729	5	52	52	NUM
fnp-3528	729	6	,	,	PUNCT
fnp-3528	729	7	956	956	NUM
fnp-3528	729	8	-	-	SYM
fnp-3528	729	9	61	61	NUM
fnp-3528	729	10	.	.	PUNCT
fnp-3528	730	1	albrecht	albrecht	PROPN
fnp-3528	730	2	,	,	PUNCT
fnp-3528	730	3	c.	c.	PROPN
fnp-3528	730	4	;	;	PUNCT
fnp-3528	730	5	viturro	viturro	PROPN
fnp-3528	730	6	,	,	PUNCT
fnp-3528	730	7	e.	e.	PROPN
fnp-3528	730	8	the	the	DET
fnp-3528	730	9	abca	abca	PROPN
fnp-3528	730	10	subfamily	subfamily	ADV
fnp-3528	730	11	--	--	PUNCT
fnp-3528	730	12	gene	gene	NOUN
fnp-3528	730	13	and	and	CCONJ
fnp-3528	730	14	protein	protein	NOUN
fnp-3528	730	15	structures	structure	NOUN
fnp-3528	730	16	,	,	PUNCT
fnp-3528	730	17	functions	function	NOUN
fnp-3528	730	18	and	and	CCONJ
fnp-3528	730	19	associated	associate	VERB
fnp-3528	730	20	hereditary	hereditary	ADJ
fnp-3528	730	21	diseases	disease	NOUN
fnp-3528	730	22	.	.	PUNCT
fnp-3528	731	1	pflugers	pfluger	NOUN
fnp-3528	731	2	arch	arch	VERB
fnp-3528	731	3	2007	2007	NUM
fnp-3528	731	4	,	,	PUNCT
fnp-3528	731	5	453	453	NUM
fnp-3528	731	6	,	,	PUNCT
fnp-3528	731	7	581	581	NUM
fnp-3528	731	8	-	-	SYM
fnp-3528	731	9	9	9	NUM
fnp-3528	731	10	.	.	PUNCT
fnp-3528	732	1	kubo	kubo	PROPN
fnp-3528	732	2	,	,	PUNCT
fnp-3528	732	3	y.	y.	PROPN
fnp-3528	732	4	;	;	PUNCT
fnp-3528	732	5	sekiya	sekiya	NOUN
fnp-3528	732	6	,	,	PUNCT
fnp-3528	732	7	s.	s.	PROPN
fnp-3528	732	8	;	;	PUNCT
fnp-3528	732	9	ohigashi	ohigashi	PROPN
fnp-3528	732	10	,	,	PUNCT
fnp-3528	732	11	m.	m.	NOUN
fnp-3528	732	12	;	;	PUNCT
fnp-3528	732	13	takenaka	takenaka	ADV
fnp-3528	732	14	,	,	PUNCT
fnp-3528	732	15	c.	c.	PROPN
fnp-3528	732	16	;	;	PUNCT
fnp-3528	732	17	tamura	tamura	PROPN
fnp-3528	732	18	,	,	PUNCT
fnp-3528	732	19	k.	k.	PROPN
fnp-3528	732	20	;	;	PUNCT
fnp-3528	732	21	nada	nada	PROPN
fnp-3528	732	22	,	,	PUNCT
fnp-3528	732	23	s.	s.	PROPN
fnp-3528	732	24	;	;	PUNCT
fnp-3528	732	25	nishi	nishi	NOUN
fnp-3528	732	26	,	,	PUNCT
fnp-3528	732	27	t.	t.	PROPN
fnp-3528	732	28	;	;	PUNCT
fnp-3528	732	29	yamamoto	yamamoto	PROPN
fnp-3528	732	30	,	,	PUNCT
fnp-3528	732	31	a.	a.	PROPN
fnp-3528	732	32	;	;	PUNCT
fnp-3528	732	33	yamaguchi	yamaguchi	PROPN
fnp-3528	732	34	,	,	PUNCT
fnp-3528	732	35	a.	a.	PROPN
fnp-3528	732	36	abca5	abca5	PROPN
fnp-3528	732	37	resides	reside	VERB
fnp-3528	732	38	in	in	ADP
fnp-3528	732	39	lysosomes	lysosome	NOUN
fnp-3528	732	40	,	,	PUNCT
fnp-3528	732	41	and	and	CCONJ
fnp-3528	732	42	abca5	abca5	X
fnp-3528	732	43	knockout	knockout	NOUN
fnp-3528	732	44	mice	mouse	NOUN
fnp-3528	732	45	develop	develop	VERB
fnp-3528	732	46	lysosomal	lysosomal	ADJ
fnp-3528	732	47	disease	disease	NOUN
fnp-3528	732	48	-	-	PUNCT
fnp-3528	732	49	like	like	ADJ
fnp-3528	732	50	symptoms	symptom	NOUN
fnp-3528	732	51	.	.	PUNCT
fnp-3528	733	1	mol	mol	ADP
fnp-3528	733	2	cell	cell	NOUN
fnp-3528	733	3	biol	biol	NOUN
fnp-3528	733	4	2005	2005	NUM
fnp-3528	733	5	,	,	PUNCT
fnp-3528	733	6	25	25	NUM
fnp-3528	733	7	,	,	PUNCT
fnp-3528	733	8	4138	4138	NUM
fnp-3528	733	9	-	-	SYM
fnp-3528	733	10	49	49	NUM
fnp-3528	733	11	.	.	PUNCT
fnp-3528	734	1	takahashi	takahashi	PROPN
fnp-3528	734	2	,	,	PUNCT
fnp-3528	734	3	k.	k.	PROPN
fnp-3528	734	4	;	;	PUNCT
fnp-3528	734	5	kimura	kimura	NOUN
fnp-3528	734	6	,	,	PUNCT
fnp-3528	734	7	y.	y.	PROPN
fnp-3528	734	8	;	;	PUNCT
fnp-3528	734	9	nagata	nagata	PROPN
fnp-3528	734	10	,	,	PUNCT
fnp-3528	734	11	k.	k.	PROPN
fnp-3528	734	12	;	;	PUNCT
fnp-3528	734	13	yamamoto	yamamoto	PROPN
fnp-3528	734	14	,	,	PUNCT
fnp-3528	734	15	a.	a.	NOUN
fnp-3528	734	16	;	;	PUNCT
fnp-3528	734	17	matsuo	matsuo	PROPN
fnp-3528	734	18	,	,	PUNCT
fnp-3528	734	19	m.	m.	NOUN
fnp-3528	734	20	;	;	PUNCT
fnp-3528	734	21	ueda	ueda	PROPN
fnp-3528	734	22	,	,	PUNCT
fnp-3528	734	23	k.	k.	PROPN
fnp-3528	734	24	abc	abc	PROPN
fnp-3528	734	25	proteins	protein	NOUN
fnp-3528	734	26	:	:	PUNCT
fnp-3528	734	27	key	key	ADJ
fnp-3528	734	28	molecules	molecule	NOUN
fnp-3528	734	29	for	for	ADP
fnp-3528	734	30	lipid	lipid	NOUN
fnp-3528	734	31	homeostasis	homeostasis	NOUN
fnp-3528	734	32	.	.	PUNCT
fnp-3528	735	1	med	me	VERB
fnp-3528	735	2	mol	mol	ADP
fnp-3528	735	3	morphol	morphol	NOUN
fnp-3528	735	4	2005	2005	NUM
fnp-3528	735	5	,	,	PUNCT
fnp-3528	735	6	38	38	NUM
fnp-3528	735	7	,	,	PUNCT
fnp-3528	735	8	2	2	NUM
fnp-3528	735	9	-	-	SYM
fnp-3528	735	10	12	12	NUM
fnp-3528	735	11	.	.	PUNCT
fnp-3528	736	1	garces	garce	NOUN
fnp-3528	736	2	,	,	PUNCT
fnp-3528	736	3	f.	f.	PROPN
fnp-3528	736	4	a.	a.	PROPN
fnp-3528	736	5	;	;	PUNCT
fnp-3528	736	6	scortecci	scortecci	PROPN
fnp-3528	736	7	,	,	PUNCT
fnp-3528	736	8	j.	j.	PROPN
fnp-3528	736	9	f.	f.	PROPN
fnp-3528	736	10	;	;	PUNCT
fnp-3528	736	11	molday	molday	PROPN
fnp-3528	736	12	,	,	PUNCT
fnp-3528	736	13	r.	r.	PROPN
fnp-3528	736	14	s.	s.	PROPN
fnp-3528	736	15	functional	functional	ADJ
fnp-3528	736	16	characterization	characterization	NOUN
fnp-3528	736	17	of	of	ADP
fnp-3528	736	18	abca4	abca4	ADJ
fnp-3528	736	19	missense	missense	NOUN
fnp-3528	736	20	variants	variant	NOUN
fnp-3528	736	21	linked	link	VERB
fnp-3528	736	22	to	to	ADP
fnp-3528	736	23	stargardt	stargardt	ADJ
fnp-3528	736	24	macular	macular	ADJ
fnp-3528	736	25	degeneration	degeneration	NOUN
fnp-3528	736	26	.	.	PUNCT
fnp-3528	737	1	int	int	PROPN
fnp-3528	737	2	j	j	PROPN
fnp-3528	737	3	mol	mol	ADP
fnp-3528	737	4	sci	sci	PROPN
fnp-3528	737	5	2020	2020	NUM
fnp-3528	737	6	,	,	PUNCT
fnp-3528	737	7	22	22	NUM
fnp-3528	737	8	,	,	PUNCT
fnp-3528	737	9	185	185	NUM
fnp-3528	737	10	.	.	PUNCT
fnp-3528	738	1	curtis	curtis	PROPN
fnp-3528	738	2	,	,	PUNCT
fnp-3528	738	3	s.	s.	PROPN
fnp-3528	738	4	b.	b.	PROPN
fnp-3528	738	5	;	;	PUNCT
fnp-3528	738	6	molday	molday	PROPN
fnp-3528	738	7	,	,	PUNCT
fnp-3528	738	8	l.	l.	PROPN
fnp-3528	738	9	l.	l.	PROPN
fnp-3528	738	10	;	;	PUNCT
fnp-3528	738	11	garces	garces	PROPN
fnp-3528	738	12	,	,	PUNCT
fnp-3528	738	13	f.	f.	PROPN
fnp-3528	738	14	a.	a.	PROPN
fnp-3528	738	15	;	;	PUNCT
fnp-3528	738	16	molday	molday	PROPN
fnp-3528	738	17	,	,	PUNCT
fnp-3528	738	18	r.	r.	PROPN
fnp-3528	738	19	s.	s.	PROPN
fnp-3528	738	20	functional	functional	ADJ
fnp-3528	738	21	analysis	analysis	NOUN
fnp-3528	738	22	and	and	CCONJ
fnp-3528	738	23	classification	classification	NOUN
fnp-3528	738	24	of	of	ADP
fnp-3528	738	25	homozygous	homozygous	ADJ
fnp-3528	738	26	and	and	CCONJ
fnp-3528	738	27	hypomorphic	hypomorphic	ADJ
fnp-3528	738	28	abca4	abca4	ADJ
fnp-3528	738	29	variants	variant	NOUN
fnp-3528	738	30	associated	associate	VERB
fnp-3528	738	31	with	with	ADP
fnp-3528	738	32	stargardt	stargardt	ADJ
fnp-3528	738	33	macular	macular	ADJ
fnp-3528	738	34	degeneration	degeneration	NOUN
fnp-3528	738	35	.	.	PUNCT
fnp-3528	739	1	hum	hum	PROPN
fnp-3528	739	2	mutat	mutat	PROPN
fnp-3528	739	3	2020	2020	NUM
fnp-3528	739	4	,	,	PUNCT
fnp-3528	739	5	41	41	NUM
fnp-3528	739	6	,	,	PUNCT
fnp-3528	739	7	1944	1944	NUM
fnp-3528	739	8	-	-	SYM
fnp-3528	739	9	1956	1956	NUM
fnp-3528	739	10	.	.	PUNCT
fnp-3528	740	1	garces	garces	PROPN
fnp-3528	740	2	,	,	PUNCT
fnp-3528	740	3	f.	f.	PROPN
fnp-3528	740	4	;	;	PUNCT
fnp-3528	740	5	jiang	jiang	PROPN
fnp-3528	740	6	,	,	PUNCT
fnp-3528	740	7	k.	k.	PROPN
fnp-3528	740	8	;	;	PUNCT
fnp-3528	740	9	molday	molday	PROPN
fnp-3528	740	10	,	,	PUNCT
fnp-3528	740	11	l.	l.	PROPN
fnp-3528	740	12	l.	l.	PROPN
fnp-3528	740	13	;	;	PUNCT
fnp-3528	740	14	stohr	stohr	NOUN
fnp-3528	740	15	,	,	PUNCT
fnp-3528	740	16	h.	h.	PROPN
fnp-3528	740	17	;	;	PUNCT
fnp-3528	740	18	weber	weber	PROPN
fnp-3528	740	19	,	,	PUNCT
fnp-3528	740	20	b.	b.	PROPN
fnp-3528	740	21	h.	h.	PROPN
fnp-3528	740	22	;	;	PUNCT
fnp-3528	740	23	lyons	lyons	PROPN
fnp-3528	740	24	,	,	PUNCT
fnp-3528	740	25	c.	c.	PROPN
fnp-3528	740	26	j.	j.	PROPN
fnp-3528	740	27	;	;	PUNCT
fnp-3528	740	28	maberley	maberley	PROPN
fnp-3528	740	29	,	,	PUNCT
fnp-3528	740	30	d.	d.	PROPN
fnp-3528	740	31	;	;	PUNCT
fnp-3528	740	32	molday	molday	PROPN
fnp-3528	740	33	,	,	PUNCT
fnp-3528	740	34	r.	r.	PROPN
fnp-3528	740	35	s.	s.	PROPN
fnp-3528	740	36	correlating	correlate	VERB
fnp-3528	740	37	the	the	DET
fnp-3528	740	38	expression	expression	NOUN
fnp-3528	740	39	and	and	CCONJ
fnp-3528	740	40	functional	functional	ADJ
fnp-3528	740	41	activity	activity	NOUN
fnp-3528	740	42	of	of	ADP
fnp-3528	740	43	abca4	abca4	ADJ
fnp-3528	740	44	disease	disease	NOUN
fnp-3528	740	45	variants	variant	NOUN
fnp-3528	740	46	with	with	ADP
fnp-3528	740	47	the	the	DET
fnp-3528	740	48	phenotype	phenotype	NOUN
fnp-3528	740	49	of	of	ADP
fnp-3528	740	50	patients	patient	NOUN
fnp-3528	740	51	with	with	ADP
fnp-3528	740	52	stargardt	stargardt	ADJ
fnp-3528	740	53	disease	disease	NOUN
fnp-3528	740	54	.	.	PUNCT
fnp-3528	741	1	invest	invest	VERB
fnp-3528	741	2	ophthalmol	ophthalmol	PROPN
fnp-3528	741	3	vis	vis	X
fnp-3528	741	4	sci	sci	PROPN
fnp-3528	741	5	2018	2018	NUM
fnp-3528	741	6	,	,	PUNCT
fnp-3528	741	7	59	59	NUM
fnp-3528	741	8	,	,	PUNCT
fnp-3528	741	9	2305	2305	NUM
fnp-3528	741	10	-	-	SYM
fnp-3528	741	11	2315	2315	NUM
fnp-3528	741	12	.	.	PUNCT
fnp-3528	742	1	quazi	quazi	PROPN
fnp-3528	742	2	,	,	PUNCT
fnp-3528	742	3	f.	f.	PROPN
fnp-3528	742	4	;	;	PUNCT
fnp-3528	742	5	lenevich	lenevich	PROPN
fnp-3528	742	6	,	,	PUNCT
fnp-3528	742	7	s.	s.	PROPN
fnp-3528	742	8	;	;	PUNCT
fnp-3528	742	9	molday	molday	PROPN
fnp-3528	742	10	,	,	PUNCT
fnp-3528	742	11	r.	r.	PROPN
fnp-3528	742	12	s.	s.	PROPN
fnp-3528	742	13	abca4	abca4	PROPN
fnp-3528	742	14	is	be	AUX
fnp-3528	742	15	an	an	DET
fnp-3528	742	16	n	n	CCONJ
fnp-3528	742	17	-	-	PUNCT
fnp-3528	742	18	retinylidene	retinylidene	NOUN
fnp-3528	742	19	-	-	PUNCT
fnp-3528	742	20	phosphatidylethanolamine	phosphatidylethanolamine	NOUN
fnp-3528	742	21	and	and	CCONJ
fnp-3528	742	22	phosphatidylethanolamine	phosphatidylethanolamine	PROPN
fnp-3528	742	23	importer	importer	NOUN
fnp-3528	742	24	.	.	PUNCT
fnp-3528	743	1	nat	nat	PROPN
fnp-3528	743	2	commun	commun	PROPN
fnp-3528	743	3	2012	2012	NUM
fnp-3528	743	4	,	,	PUNCT
fnp-3528	743	5	3	3	NUM
fnp-3528	743	6	,	,	PUNCT
fnp-3528	743	7	925	925	NUM
fnp-3528	743	8	.	.	PUNCT
fnp-3528	743	9	ahn	ahn	PROPN
fnp-3528	743	10	,	,	PUNCT
fnp-3528	743	11	j.	j.	PROPN
fnp-3528	743	12	;	;	PUNCT
fnp-3528	743	13	wong	wong	PROPN
fnp-3528	743	14	,	,	PUNCT
fnp-3528	743	15	j.	j.	PROPN
fnp-3528	743	16	t.	t.	PROPN
fnp-3528	743	17	;	;	PUNCT
fnp-3528	743	18	molday	molday	PROPN
fnp-3528	743	19	,	,	PUNCT
fnp-3528	743	20	r.	r.	PROPN
fnp-3528	743	21	s.	s.	PROPN
fnp-3528	743	22	the	the	DET
fnp-3528	743	23	effect	effect	NOUN
fnp-3528	743	24	of	of	ADP
fnp-3528	743	25	lipid	lipid	ADJ
fnp-3528	743	26	environment	environment	NOUN
fnp-3528	743	27	and	and	CCONJ
fnp-3528	743	28	retinoids	retinoid	NOUN
fnp-3528	743	29	on	on	ADP
fnp-3528	743	30	the	the	DET
fnp-3528	743	31	atpase	atpase	PROPN
fnp-3528	743	32	activity	activity	NOUN
fnp-3528	743	33	of	of	ADP
fnp-3528	743	34	abcr	abcr	NOUN
fnp-3528	743	35	,	,	PUNCT
fnp-3528	743	36	the	the	DET
fnp-3528	743	37	photoreceptor	photoreceptor	NOUN
fnp-3528	743	38	abc	abc	PROPN
fnp-3528	743	39	transporter	transporter	VERB
fnp-3528	743	40	responsible	responsible	ADJ
fnp-3528	743	41	for	for	ADP
fnp-3528	743	42	stargardt	stargardt	ADJ
fnp-3528	743	43	macular	macular	ADJ
fnp-3528	743	44	dystrophy	dystrophy	NOUN
fnp-3528	743	45	.	.	PUNCT
fnp-3528	744	1	j	j	PROPN
fnp-3528	744	2	biol	biol	PROPN
fnp-3528	744	3	chem	chem	NOUN
fnp-3528	744	4	2000	2000	NUM
fnp-3528	744	5	,	,	PUNCT
fnp-3528	744	6	275	275	NUM
fnp-3528	744	7	,	,	PUNCT
fnp-3528	744	8	20399	20399	NUM
fnp-3528	744	9	-	-	SYM
fnp-3528	744	10	405	405	NUM
fnp-3528	744	11	.	.	PUNCT
fnp-3528	745	1	sun	sun	PROPN
fnp-3528	745	2	,	,	PUNCT
fnp-3528	745	3	h.	h.	PROPN
fnp-3528	745	4	;	;	PUNCT
fnp-3528	745	5	molday	molday	PROPN
fnp-3528	745	6	,	,	PUNCT
fnp-3528	745	7	r.	r.	PROPN
fnp-3528	745	8	s.	s.	PROPN
fnp-3528	745	9	;	;	PUNCT
fnp-3528	745	10	nathans	nathans	PROPN
fnp-3528	745	11	,	,	PUNCT
fnp-3528	745	12	j.	j.	PROPN
fnp-3528	745	13	retinal	retinal	PROPN
fnp-3528	745	14	stimulates	stimulate	VERB
fnp-3528	745	15	atp	atp	NOUN
fnp-3528	745	16	hydrolysis	hydrolysis	NOUN
fnp-3528	745	17	by	by	ADP
fnp-3528	745	18	purified	purified	ADJ
fnp-3528	745	19	and	and	CCONJ
fnp-3528	745	20	reconstituted	reconstitute	VERB
fnp-3528	745	21	abcr	abcr	NOUN
fnp-3528	745	22	,	,	PUNCT
fnp-3528	745	23	the	the	DET
fnp-3528	745	24	photoreceptor	photoreceptor	NOUN
fnp-3528	745	25	-	-	PUNCT
fnp-3528	745	26	specific	specific	ADJ
fnp-3528	745	27	atp	atp	NOUN
fnp-3528	745	28	-	-	PUNCT
fnp-3528	745	29	binding	bind	VERB
fnp-3528	745	30	cassette	cassette	NOUN
fnp-3528	745	31	transporter	transporter	NOUN
fnp-3528	745	32	responsible	responsible	ADJ
fnp-3528	745	33	for	for	ADP
fnp-3528	745	34	stargardt	stargardt	ADJ
fnp-3528	745	35	disease	disease	NOUN
fnp-3528	745	36	.	.	PUNCT
fnp-3528	746	1	j	j	PROPN
fnp-3528	746	2	biol	biol	PROPN
fnp-3528	746	3	chem	chem	NOUN
fnp-3528	746	4	1999	1999	NUM
fnp-3528	746	5	,	,	PUNCT
fnp-3528	746	6	274	274	NUM
fnp-3528	746	7	,	,	PUNCT
fnp-3528	746	8	8269	8269	NUM
fnp-3528	746	9	-	-	SYM
fnp-3528	746	10	81	81	NUM
fnp-3528	746	11	.	.	PUNCT
fnp-3528	747	1	wambach	wambach	PROPN
fnp-3528	747	2	,	,	PUNCT
fnp-3528	747	3	j.	j.	PROPN
fnp-3528	747	4	a.	a.	PROPN
fnp-3528	747	5	;	;	PUNCT
fnp-3528	747	6	yang	yang	PROPN
fnp-3528	747	7	,	,	PUNCT
fnp-3528	747	8	p.	p.	PROPN
fnp-3528	747	9	;	;	PUNCT
fnp-3528	747	10	wegner	wegner	PROPN
fnp-3528	747	11	,	,	PUNCT
fnp-3528	747	12	d.	d.	PROPN
fnp-3528	747	13	j.	j.	PROPN
fnp-3528	747	14	;	;	PUNCT
fnp-3528	747	15	heins	heins	PROPN
fnp-3528	747	16	,	,	PUNCT
fnp-3528	747	17	h.	h.	PROPN
fnp-3528	747	18	b.	b.	PROPN
fnp-3528	747	19	;	;	PUNCT
fnp-3528	747	20	kaliberova	kaliberova	PROPN
fnp-3528	747	21	,	,	PUNCT
fnp-3528	747	22	l.	l.	PROPN
fnp-3528	747	23	n.	n.	PROPN
fnp-3528	747	24	;	;	PUNCT
fnp-3528	747	25	kaliberov	kaliberov	PROPN
fnp-3528	747	26	,	,	PUNCT
fnp-3528	747	27	s.	s.	PROPN
fnp-3528	747	28	a.	a.	PROPN
fnp-3528	747	29	;	;	PUNCT
fnp-3528	747	30	curiel	curiel	PROPN
fnp-3528	747	31	,	,	PUNCT
fnp-3528	747	32	d.	d.	PROPN
fnp-3528	747	33	t.	t.	PROPN
fnp-3528	747	34	;	;	PUNCT
fnp-3528	747	35	white	white	PROPN
fnp-3528	747	36	,	,	PUNCT
fnp-3528	747	37	f.	f.	PROPN
fnp-3528	747	38	v.	v.	PROPN
fnp-3528	747	39	;	;	PUNCT
fnp-3528	747	40	hamvas	hamvas	PROPN
fnp-3528	747	41	,	,	PUNCT
fnp-3528	747	42	a.	a.	NOUN
fnp-3528	747	43	;	;	PUNCT
fnp-3528	747	44	hackett	hackett	PROPN
fnp-3528	747	45	,	,	PUNCT
fnp-3528	747	46	b.	b.	PROPN
fnp-3528	747	47	p.	p.	PROPN
fnp-3528	747	48	;	;	PUNCT
fnp-3528	747	49	cole	cole	PROPN
fnp-3528	747	50	,	,	PUNCT
fnp-3528	747	51	f.	f.	PROPN
fnp-3528	747	52	s.	s.	PROPN
fnp-3528	747	53	functional	functional	ADJ
fnp-3528	747	54	characterization	characterization	NOUN
fnp-3528	747	55	of	of	ADP
fnp-3528	747	56	atp	atp	NOUN
fnp-3528	747	57	-	-	PUNCT
fnp-3528	747	58	binding	bind	VERB
fnp-3528	747	59	cassette	cassette	NOUN
fnp-3528	747	60	transporter	transporter	NOUN
fnp-3528	747	61	a3	a3	NOUN
fnp-3528	747	62	mutations	mutation	NOUN
fnp-3528	747	63	from	from	ADP
fnp-3528	747	64	infants	infant	NOUN
fnp-3528	747	65	with	with	ADP
fnp-3528	747	66	respiratory	respiratory	ADJ
fnp-3528	747	67	distress	distress	NOUN
fnp-3528	747	68	syndrome	syndrome	NOUN
fnp-3528	747	69	.	.	PUNCT
fnp-3528	748	1	am	be	AUX
fnp-3528	748	2	j	j	PROPN
fnp-3528	748	3	respir	respir	NOUN
fnp-3528	748	4	cell	cell	NOUN
fnp-3528	748	5	mol	mol	ADP
fnp-3528	748	6	biol	biol	PROPN
fnp-3528	748	7	2016	2016	NUM
fnp-3528	748	8	,	,	PUNCT
fnp-3528	748	9	55	55	NUM
fnp-3528	748	10	,	,	PUNCT
fnp-3528	748	11	716	716	NUM
fnp-3528	748	12	-	-	SYM
fnp-3528	748	13	21	21	NUM
fnp-3528	748	14	.	.	PUNCT
fnp-3528	749	1	nathan	nathan	PROPN
fnp-3528	749	2	,	,	PUNCT
fnp-3528	749	3	n.	n.	PROPN
fnp-3528	749	4	;	;	PUNCT
fnp-3528	749	5	berdah	berdah	PROPN
fnp-3528	749	6	,	,	PUNCT
fnp-3528	749	7	l.	l.	PROPN
fnp-3528	749	8	;	;	PUNCT
fnp-3528	749	9	delestrain	delestrain	PROPN
fnp-3528	749	10	,	,	PUNCT
fnp-3528	749	11	c.	c.	PROPN
fnp-3528	749	12	;	;	PUNCT
fnp-3528	749	13	sileo	sileo	PROPN
fnp-3528	749	14	,	,	PUNCT
fnp-3528	749	15	c.	c.	PROPN
fnp-3528	749	16	;	;	PUNCT
fnp-3528	749	17	clement	clement	PROPN
fnp-3528	749	18	,	,	PUNCT
fnp-3528	749	19	a.	a.	NOUN
fnp-3528	749	20	interstitial	interstitial	ADJ
fnp-3528	749	21	lung	lung	NOUN
fnp-3528	749	22	diseases	disease	NOUN
fnp-3528	749	23	in	in	ADP
fnp-3528	749	24	children	child	NOUN
fnp-3528	749	25	.	.	PUNCT
fnp-3528	750	1	presse	presse	PROPN
fnp-3528	750	2	med	med	PROPN
fnp-3528	750	3	2020	2020	NUM
fnp-3528	750	4	,	,	PUNCT
fnp-3528	750	5	49	49	NUM
fnp-3528	750	6	,	,	PUNCT
fnp-3528	750	7	103909	103909	NUM
fnp-3528	750	8	.	.	PUNCT
fnp-3528	751	1	chen	chen	PROPN
fnp-3528	751	2	,	,	PUNCT
fnp-3528	751	3	p.	p.	PROPN
fnp-3528	751	4	;	;	PUNCT
fnp-3528	751	5	dai	dai	PROPN
fnp-3528	751	6	,	,	PUNCT
fnp-3528	751	7	y.	y.	PROPN
fnp-3528	751	8	;	;	PUNCT
fnp-3528	751	9	wu	wu	PROPN
fnp-3528	751	10	,	,	PUNCT
fnp-3528	751	11	x.	x.	PROPN
fnp-3528	751	12	;	;	PUNCT
fnp-3528	751	13	wang	wang	PROPN
fnp-3528	751	14	,	,	PUNCT
fnp-3528	751	15	y.	y.	PROPN
fnp-3528	751	16	;	;	PUNCT
fnp-3528	751	17	sun	sun	PROPN
fnp-3528	751	18	,	,	PUNCT
fnp-3528	751	19	s.	s.	PROPN
fnp-3528	751	20	;	;	PUNCT
fnp-3528	751	21	xiao	xiao	PROPN
fnp-3528	751	22	,	,	PUNCT
fnp-3528	751	23	j.	j.	PROPN
fnp-3528	751	24	;	;	PUNCT
fnp-3528	751	25	zhang	zhang	PROPN
fnp-3528	751	26	,	,	PUNCT
fnp-3528	751	27	q.	q.	PROPN
fnp-3528	751	28	;	;	PUNCT
fnp-3528	751	29	guan	guan	PROPN
fnp-3528	751	30	,	,	PUNCT
fnp-3528	751	31	l.	l.	PROPN
fnp-3528	751	32	;	;	PUNCT
fnp-3528	751	33	zhao	zhao	PROPN
fnp-3528	751	34	,	,	PUNCT
fnp-3528	751	35	x.	x.	PROPN
fnp-3528	751	36	;	;	PUNCT
fnp-3528	751	37	hao	hao	PROPN
fnp-3528	751	38	,	,	PUNCT
fnp-3528	751	39	x.	x.	PROPN
fnp-3528	751	40	;	;	PUNCT
fnp-3528	751	41	wu	wu	PROPN
fnp-3528	751	42	,	,	PUNCT
fnp-3528	751	43	r.	r.	PROPN
fnp-3528	751	44	;	;	PUNCT
fnp-3528	751	45	xie	xie	PROPN
fnp-3528	751	46	,	,	PUNCT
fnp-3528	751	47	l.	l.	PROPN
fnp-3528	751	48	mutations	mutation	NOUN
fnp-3528	751	49	in	in	ADP
fnp-3528	751	50	the	the	DET
fnp-3528	751	51	abca3	abca3	PROPN
fnp-3528	751	52	gene	gene	NOUN
fnp-3528	751	53	are	be	AUX
fnp-3528	751	54	associated	associate	VERB
fnp-3528	751	55	with	with	ADP
fnp-3528	751	56	cataract	cataract	NOUN
fnp-3528	751	57	-	-	PUNCT
fnp-3528	751	58	microcornea	microcornea	NOUN
fnp-3528	751	59	syndrome	syndrome	NOUN
fnp-3528	751	60	.	.	PUNCT
fnp-3528	752	1	invest	invest	VERB
fnp-3528	752	2	ophthalmol	ophthalmol	PROPN
fnp-3528	752	3	vis	vis	X
fnp-3528	752	4	sci	sci	PROPN
fnp-3528	752	5	2014	2014	NUM
fnp-3528	752	6	,	,	PUNCT
fnp-3528	752	7	55	55	NUM
fnp-3528	752	8	,	,	PUNCT
fnp-3528	752	9	8031	8031	NUM
fnp-3528	752	10	-	-	SYM
fnp-3528	752	11	43	43	NUM
fnp-3528	752	12	.	.	PUNCT
fnp-3528	753	1	destefano	destefano	PROPN
fnp-3528	753	2	,	,	PUNCT
fnp-3528	753	3	g.	g.	PROPN
fnp-3528	753	4	m.	m.	PROPN
fnp-3528	753	5	;	;	PUNCT
fnp-3528	753	6	kurban	kurban	PROPN
fnp-3528	753	7	,	,	PUNCT
fnp-3528	753	8	m.	m.	NOUN
fnp-3528	753	9	;	;	PUNCT
fnp-3528	753	10	anyane	anyane	PROPN
fnp-3528	753	11	-	-	PUNCT
fnp-3528	753	12	yeboa	yeboa	PROPN
fnp-3528	753	13	,	,	PUNCT
fnp-3528	753	14	k.	k.	PROPN
fnp-3528	753	15	;	;	PUNCT
fnp-3528	753	16	dall'armi	dall'armi	PROPN
fnp-3528	753	17	,	,	PUNCT
fnp-3528	753	18	c.	c.	NOUN
fnp-3528	753	19	;	;	PUNCT
fnp-3528	753	20	di	di	PROPN
fnp-3528	753	21	paolo	paolo	PROPN
fnp-3528	753	22	,	,	PUNCT
fnp-3528	753	23	g.	g.	PROPN
fnp-3528	753	24	;	;	PUNCT
fnp-3528	753	25	feenstra	feenstra	PROPN
fnp-3528	753	26	,	,	PUNCT
fnp-3528	753	27	h.	h.	PROPN
fnp-3528	753	28	;	;	PUNCT
fnp-3528	753	29	silverberg	silverberg	PROPN
fnp-3528	753	30	,	,	PUNCT
fnp-3528	753	31	n.	n.	NOUN
fnp-3528	753	32	;	;	PUNCT
fnp-3528	753	33	rohena	rohena	PROPN
fnp-3528	753	34	,	,	PUNCT
fnp-3528	753	35	l.	l.	PROPN
fnp-3528	753	36	;	;	PUNCT
fnp-3528	753	37	lopez	lopez	PROPN
fnp-3528	753	38	-	-	PUNCT
fnp-3528	753	39	cepeda	cepeda	PROPN
fnp-3528	753	40	,	,	PUNCT
fnp-3528	753	41	l.	l.	PROPN
fnp-3528	753	42	d.	d.	PROPN
fnp-3528	753	43	;	;	PUNCT
fnp-3528	753	44	jobanputra	jobanputra	PROPN
fnp-3528	753	45	,	,	PUNCT
fnp-3528	753	46	v.	v.	ADV
fnp-3528	753	47	;	;	PUNCT
fnp-3528	753	48	fantauzzo	fantauzzo	X
fnp-3528	753	49	,	,	PUNCT
fnp-3528	753	50	k.	k.	PROPN
fnp-3528	753	51	a.	a.	PROPN
fnp-3528	753	52	;	;	PUNCT
fnp-3528	753	53	kiuru	kiuru	PROPN
fnp-3528	753	54	,	,	PUNCT
fnp-3528	753	55	m.	m.	NOUN
fnp-3528	753	56	;	;	PUNCT
fnp-3528	753	57	tadin	tadin	NOUN
fnp-3528	753	58	-	-	PUNCT
fnp-3528	753	59	strapps	strapp	NOUN
fnp-3528	753	60	,	,	PUNCT
fnp-3528	753	61	m.	m.	NOUN
fnp-3528	753	62	;	;	PUNCT
fnp-3528	753	63	sobrino	sobrino	PROPN
fnp-3528	753	64	,	,	PUNCT
fnp-3528	753	65	a.	a.	NOUN
fnp-3528	753	66	;	;	PUNCT
fnp-3528	753	67	vitebsky	vitebsky	PROPN
fnp-3528	753	68	,	,	PUNCT
fnp-3528	753	69	a.	a.	PROPN
fnp-3528	753	70	;	;	PUNCT
fnp-3528	753	71	warburton	warburton	PROPN
fnp-3528	753	72	,	,	PUNCT
fnp-3528	753	73	d.	d.	PROPN
fnp-3528	753	74	;	;	PUNCT
fnp-3528	753	75	levy	levy	PROPN
fnp-3528	753	76	,	,	PUNCT
fnp-3528	753	77	b.	b.	PROPN
fnp-3528	753	78	;	;	PUNCT
fnp-3528	753	79	salas	salas	PROPN
fnp-3528	753	80	-	-	PUNCT
fnp-3528	753	81	alanis	alanis	PROPN
fnp-3528	753	82	,	,	PUNCT
fnp-3528	753	83	j.	j.	PROPN
fnp-3528	753	84	c.	c.	PROPN
fnp-3528	753	85	;	;	PUNCT
fnp-3528	753	86	christiano	christiano	PROPN
fnp-3528	753	87	,	,	PUNCT
fnp-3528	753	88	a.	a.	NOUN
fnp-3528	753	89	m.	m.	NOUN
fnp-3528	753	90	mutations	mutation	NOUN
fnp-3528	753	91	in	in	ADP
fnp-3528	753	92	the	the	DET
fnp-3528	753	93	cholesterol	cholesterol	NOUN
fnp-3528	753	94	transporter	transporter	NOUN
fnp-3528	753	95	gene	gene	NOUN
fnp-3528	753	96	abca5	abca5	NOUN
fnp-3528	753	97	are	be	AUX
fnp-3528	753	98	associated	associate	VERB
fnp-3528	753	99	with	with	ADP
fnp-3528	753	100	excessive	excessive	ADJ
fnp-3528	753	101	hair	hair	NOUN
fnp-3528	753	102	overgrowth	overgrowth	NOUN
fnp-3528	753	103	.	.	PUNCT
fnp-3528	754	1	plos	plos	PROPN
fnp-3528	754	2	genetics	genetics	PROPN
fnp-3528	754	3	2014	2014	NUM
fnp-3528	754	4	,	,	PUNCT
fnp-3528	754	5	10	10	NUM
fnp-3528	754	6	,	,	PUNCT
fnp-3528	754	7	e1004333	e1004333	NUM
fnp-3528	754	8	.	.	PUNCT
fnp-3528	755	1	elkhatib	elkhatib	PROPN
fnp-3528	755	2	,	,	PUNCT
fnp-3528	755	3	a.	a.	NOUN
fnp-3528	755	4	m.	m.	NOUN
fnp-3528	755	5	;	;	PUNCT
fnp-3528	755	6	omar	omar	PROPN
fnp-3528	755	7	,	,	PUNCT
fnp-3528	755	8	m.	m.	NOUN
fnp-3528	755	9	ichthyosis	ichthyosis	NOUN
fnp-3528	755	10	fetalis	fetali	NOUN
fnp-3528	755	11	.	.	PUNCT
fnp-3528	756	1	in	in	ADP
fnp-3528	756	2	statpearls	statpearl	NOUN
fnp-3528	756	3	,	,	PUNCT
fnp-3528	756	4	treasure	treasure	NOUN
fnp-3528	756	5	island	island	NOUN
fnp-3528	756	6	(	(	PUNCT
fnp-3528	756	7	fl	fl	NOUN
fnp-3528	756	8	)	)	PUNCT
fnp-3528	756	9	,	,	PUNCT
fnp-3528	756	10	2021	2021	NUM
fnp-3528	756	11	.	.	PUNCT
fnp-3528	757	1	zarubica	zarubica	PROPN
fnp-3528	757	2	,	,	PUNCT
fnp-3528	757	3	a.	a.	NOUN
fnp-3528	757	4	;	;	PUNCT
fnp-3528	757	5	trompier	trompier	NOUN
fnp-3528	757	6	,	,	PUNCT
fnp-3528	757	7	d.	d.	PROPN
fnp-3528	757	8	;	;	PUNCT
fnp-3528	757	9	chimini	chimini	PROPN
fnp-3528	757	10	,	,	PUNCT
fnp-3528	757	11	g.	g.	PROPN
fnp-3528	757	12	abca1	abca1	PROPN
fnp-3528	757	13	,	,	PUNCT
fnp-3528	757	14	from	from	ADP
fnp-3528	757	15	pathology	pathology	NOUN
fnp-3528	757	16	to	to	ADP
fnp-3528	757	17	membrane	membrane	NOUN
fnp-3528	757	18	function	function	NOUN
fnp-3528	757	19	.	.	PUNCT
fnp-3528	758	1	pflugers	pfluger	NOUN
fnp-3528	758	2	arch	arch	VERB
fnp-3528	758	3	2007	2007	NUM
fnp-3528	758	4	,	,	PUNCT
fnp-3528	758	5	453	453	NUM
fnp-3528	758	6	,	,	PUNCT
fnp-3528	758	7	569	569	NUM
fnp-3528	758	8	-	-	SYM
fnp-3528	758	9	79	79	NUM
fnp-3528	758	10	.	.	PUNCT
fnp-3528	759	1	luciani	luciani	PROPN
fnp-3528	759	2	,	,	PUNCT
fnp-3528	759	3	m.	m.	PROPN
fnp-3528	759	4	f.	f.	PROPN
fnp-3528	759	5	;	;	PUNCT
fnp-3528	759	6	denizot	denizot	PROPN
fnp-3528	759	7	,	,	PUNCT
fnp-3528	759	8	f.	f.	PROPN
fnp-3528	759	9	;	;	PUNCT
fnp-3528	759	10	savary	savary	PROPN
fnp-3528	759	11	,	,	PUNCT
fnp-3528	759	12	s.	s.	PROPN
fnp-3528	759	13	;	;	PUNCT
fnp-3528	759	14	mattei	mattei	NOUN
fnp-3528	759	15	,	,	PUNCT
fnp-3528	759	16	m.	m.	NOUN
fnp-3528	759	17	g.	g.	PROPN
fnp-3528	759	18	;	;	PUNCT
fnp-3528	759	19	chimini	chimini	PROPN
fnp-3528	759	20	,	,	PUNCT
fnp-3528	759	21	g.	g.	PROPN
fnp-3528	759	22	cloning	cloning	NOUN
fnp-3528	759	23	of	of	ADP
fnp-3528	759	24	two	two	NUM
fnp-3528	759	25	novel	novel	ADJ
fnp-3528	759	26	abc	abc	PROPN
fnp-3528	759	27	transporters	transporter	NOUN
fnp-3528	759	28	mapping	mapping	NOUN
fnp-3528	759	29	on	on	ADP
fnp-3528	759	30	human	human	ADJ
fnp-3528	759	31	chromosome	chromosome	NOUN
fnp-3528	759	32	9	9	NUM
fnp-3528	759	33	.	.	PUNCT
fnp-3528	760	1	genomics	genomic	NOUN
fnp-3528	760	2	1994	1994	NUM
fnp-3528	760	3	,	,	PUNCT
fnp-3528	760	4	21	21	NUM
fnp-3528	760	5	,	,	PUNCT
fnp-3528	760	6	150	150	NUM
fnp-3528	760	7	-	-	SYM
fnp-3528	760	8	9	9	NUM
fnp-3528	760	9	.	.	PUNCT
fnp-3528	761	1	santamarina	santamarina	NOUN
fnp-3528	761	2	-	-	PUNCT
fnp-3528	761	3	fojo	fojo	NOUN
fnp-3528	761	4	,	,	PUNCT
fnp-3528	761	5	s.	s.	PROPN
fnp-3528	761	6	;	;	PUNCT
fnp-3528	761	7	peterson	peterson	PROPN
fnp-3528	761	8	,	,	PUNCT
fnp-3528	761	9	k.	k.	PROPN
fnp-3528	761	10	;	;	PUNCT
fnp-3528	761	11	knapper	knapper	PROPN
fnp-3528	761	12	,	,	PUNCT
fnp-3528	761	13	c.	c.	PROPN
fnp-3528	761	14	;	;	PUNCT
fnp-3528	761	15	qiu	qiu	PROPN
fnp-3528	761	16	,	,	PUNCT
fnp-3528	761	17	y.	y.	PROPN
fnp-3528	761	18	;	;	PUNCT
fnp-3528	761	19	freeman	freeman	PROPN
fnp-3528	761	20	,	,	PUNCT
fnp-3528	761	21	l.	l.	PROPN
fnp-3528	761	22	;	;	PUNCT
fnp-3528	761	23	cheng	cheng	PROPN
fnp-3528	761	24	,	,	PUNCT
fnp-3528	761	25	j.	j.	PROPN
fnp-3528	761	26	f.	f.	PROPN
fnp-3528	761	27	;	;	PUNCT
fnp-3528	761	28	osorio	osorio	PROPN
fnp-3528	761	29	,	,	PUNCT
fnp-3528	761	30	j.	j.	PROPN
fnp-3528	761	31	;	;	PUNCT
fnp-3528	761	32	remaley	remaley	PROPN
fnp-3528	761	33	,	,	PUNCT
fnp-3528	761	34	a.	a.	PROPN
fnp-3528	761	35	;	;	PUNCT
fnp-3528	761	36	yang	yang	PROPN
fnp-3528	761	37	,	,	PUNCT
fnp-3528	761	38	x.	x.	PROPN
fnp-3528	761	39	p.	p.	PROPN
fnp-3528	761	40	;	;	PUNCT
fnp-3528	761	41	haudenschild	haudenschild	PROPN
fnp-3528	761	42	,	,	PUNCT
fnp-3528	761	43	c.	c.	NOUN
fnp-3528	761	44	;	;	PUNCT
fnp-3528	761	45	prades	prade	NOUN
fnp-3528	761	46	,	,	PUNCT
fnp-3528	761	47	c.	c.	NOUN
fnp-3528	761	48	;	;	PUNCT
fnp-3528	761	49	chimini	chimini	PROPN
fnp-3528	761	50	,	,	PUNCT
fnp-3528	761	51	g.	g.	PROPN
fnp-3528	761	52	;	;	PUNCT
fnp-3528	761	53	blackmon	blackmon	PROPN
fnp-3528	761	54	,	,	PUNCT
fnp-3528	761	55	e.	e.	PROPN
fnp-3528	761	56	;	;	PUNCT
fnp-3528	761	57	francois	francois	PROPN
fnp-3528	761	58	,	,	PUNCT
fnp-3528	761	59	t.	t.	PROPN
fnp-3528	761	60	;	;	PUNCT
fnp-3528	761	61	duverger	duverger	NOUN
fnp-3528	761	62	,	,	PUNCT
fnp-3528	761	63	n.	n.	PROPN
fnp-3528	761	64	;	;	PUNCT
fnp-3528	761	65	rubin	rubin	PROPN
fnp-3528	761	66	,	,	PUNCT
fnp-3528	761	67	e.	e.	PROPN
fnp-3528	761	68	m.	m.	PROPN
fnp-3528	761	69	;	;	PUNCT
fnp-3528	761	70	rosier	rosier	X
fnp-3528	761	71	,	,	PUNCT
fnp-3528	761	72	m.	m.	NOUN
fnp-3528	761	73	;	;	PUNCT
fnp-3528	761	74	denefle	denefle	VERB
fnp-3528	761	75	,	,	PUNCT
fnp-3528	761	76	p.	p.	PROPN
fnp-3528	761	77	;	;	PUNCT
fnp-3528	761	78	fredrickson	fredrickson	PROPN
fnp-3528	761	79	,	,	PUNCT
fnp-3528	761	80	d.	d.	PROPN
fnp-3528	761	81	s.	s.	PROPN
fnp-3528	761	82	;	;	PUNCT
fnp-3528	761	83	brewer	brewer	PROPN
fnp-3528	761	84	,	,	PUNCT
fnp-3528	761	85	h.	h.	PROPN
fnp-3528	761	86	b.	b.	PROPN
fnp-3528	761	87	,	,	PUNCT
fnp-3528	761	88	jr	jr	PROPN
fnp-3528	761	89	.	.	PROPN
fnp-3528	761	90	complete	complete	ADJ
fnp-3528	761	91	genomic	genomic	ADJ
fnp-3528	761	92	sequence	sequence	NOUN
fnp-3528	761	93	of	of	ADP
fnp-3528	761	94	the	the	DET
fnp-3528	761	95	human	human	ADJ
fnp-3528	761	96	abca1	abca1	NOUN
fnp-3528	761	97	gene	gene	NOUN
fnp-3528	761	98	:	:	PUNCT
fnp-3528	761	99	analysis	analysis	NOUN
fnp-3528	761	100	of	of	ADP
fnp-3528	761	101	the	the	DET
fnp-3528	761	102	human	human	ADJ
fnp-3528	761	103	and	and	CCONJ
fnp-3528	761	104	mouse	mouse	PROPN
fnp-3528	761	105	atp	atp	NOUN
fnp-3528	761	106	-	-	PUNCT
fnp-3528	761	107	binding	bind	VERB
fnp-3528	761	108	cassette	cassette	NOUN
fnp-3528	761	109	a	a	DET
fnp-3528	761	110	promoter	promoter	NOUN
fnp-3528	761	111	.	.	PUNCT
fnp-3528	762	1	proc	proc	PROPN
fnp-3528	762	2	natl	natl	PROPN
fnp-3528	762	3	acad	acad	PROPN
fnp-3528	762	4	sci	sci	PROPN
fnp-3528	762	5	u	u	PROPN
fnp-3528	762	6	s	s	PROPN
fnp-3528	762	7	a	a	PRON
fnp-3528	762	8	2000	2000	NUM
fnp-3528	762	9	,	,	PUNCT
fnp-3528	762	10	97	97	NUM
fnp-3528	762	11	,	,	PUNCT
fnp-3528	762	12	7987	7987	NUM
fnp-3528	762	13	-	-	SYM
fnp-3528	762	14	92	92	NUM
fnp-3528	762	15	.	.	PUNCT
fnp-3528	762	16	tang	tang	PROPN
fnp-3528	762	17	,	,	PUNCT
fnp-3528	762	18	c.	c.	PROPN
fnp-3528	762	19	;	;	PUNCT
fnp-3528	762	20	oram	oram	PROPN
fnp-3528	762	21	,	,	PUNCT
fnp-3528	762	22	j.	j.	PROPN
fnp-3528	762	23	f.	f.	PROPN
fnp-3528	763	1	the	the	DET
fnp-3528	763	2	cell	cell	NOUN
fnp-3528	763	3	cholesterol	cholesterol	NOUN
fnp-3528	763	4	exporter	exporter	NOUN
fnp-3528	763	5	abca1	abca1	NOUN
fnp-3528	763	6	as	as	ADP
fnp-3528	763	7	a	a	DET
fnp-3528	763	8	protector	protector	NOUN
fnp-3528	763	9	from	from	ADP
fnp-3528	763	10	cardiovascular	cardiovascular	ADJ
fnp-3528	763	11	disease	disease	NOUN
fnp-3528	763	12	and	and	CCONJ
fnp-3528	763	13	diabetes	diabetes	NOUN
fnp-3528	763	14	.	.	PUNCT
fnp-3528	764	1	biochim	biochim	PROPN
fnp-3528	764	2	biophys	biophy	NOUN
fnp-3528	764	3	acta	acta	PROPN
fnp-3528	764	4	2009	2009	NUM
fnp-3528	764	5	,	,	PUNCT
fnp-3528	764	6	1791	1791	NUM
fnp-3528	764	7	,	,	PUNCT
fnp-3528	764	8	563	563	NUM
fnp-3528	764	9	-	-	SYM
fnp-3528	764	10	72	72	NUM
fnp-3528	764	11	.	.	PUNCT
fnp-3528	765	1	oram	oram	PROPN
fnp-3528	765	2	,	,	PUNCT
fnp-3528	765	3	j.	j.	PROPN
fnp-3528	765	4	f.	f.	PROPN
fnp-3528	765	5	;	;	PUNCT
fnp-3528	765	6	lawn	lawn	NOUN
fnp-3528	765	7	,	,	PUNCT
fnp-3528	765	8	r.	r.	PROPN
fnp-3528	765	9	m.	m.	PROPN
fnp-3528	765	10	abca1	abca1	PROPN
fnp-3528	765	11	.	.	PUNCT
fnp-3528	766	1	the	the	DET
fnp-3528	766	2	gatekeeper	gatekeeper	NOUN
fnp-3528	766	3	for	for	ADP
fnp-3528	766	4	eliminating	eliminate	VERB
fnp-3528	766	5	excess	excess	ADJ
fnp-3528	766	6	tissue	tissue	NOUN
fnp-3528	766	7	cholesterol	cholesterol	NOUN
fnp-3528	766	8	.	.	PUNCT
fnp-3528	767	1	j	j	PROPN
fnp-3528	767	2	lipid	lipid	PROPN
fnp-3528	767	3	res	re	NOUN
fnp-3528	767	4	2001	2001	NUM
fnp-3528	767	5	,	,	PUNCT
fnp-3528	767	6	42	42	NUM
fnp-3528	767	7	,	,	PUNCT
fnp-3528	767	8	1173	1173	NUM
fnp-3528	767	9	-	-	SYM
fnp-3528	767	10	9	9	NUM
fnp-3528	767	11	.	.	PUNCT
fnp-3528	768	1	hafiane	hafiane	PROPN
fnp-3528	768	2	,	,	PUNCT
fnp-3528	768	3	a.	a.	NOUN
fnp-3528	768	4	;	;	PUNCT
fnp-3528	768	5	gianopoulos	gianopoulos	PROPN
fnp-3528	768	6	,	,	PUNCT
fnp-3528	768	7	i.	i.	NOUN
fnp-3528	768	8	;	;	PUNCT
fnp-3528	768	9	sorci	sorci	PROPN
fnp-3528	768	10	-	-	PUNCT
fnp-3528	768	11	thomas	thomas	PROPN
fnp-3528	768	12	,	,	PUNCT
fnp-3528	768	13	m.	m.	NOUN
fnp-3528	768	14	g.	g.	PROPN
fnp-3528	768	15	;	;	PUNCT
fnp-3528	768	16	daskalopoulou	daskalopoulou	PROPN
fnp-3528	768	17	,	,	PUNCT
fnp-3528	768	18	s.	s.	PROPN
fnp-3528	768	19	s.	s.	PROPN
fnp-3528	768	20	current	current	ADJ
fnp-3528	768	21	models	model	NOUN
fnp-3528	768	22	of	of	ADP
fnp-3528	768	23	apolipoprotein	apolipoprotein	ADJ
fnp-3528	768	24	a	a	PRON
fnp-3528	768	25	-	-	PUNCT
fnp-3528	768	26	i	i	PRON
fnp-3528	768	27	lipidation	lipidation	NOUN
fnp-3528	768	28	by	by	ADP
fnp-3528	768	29	adenosine	adenosine	ADJ
fnp-3528	768	30	triphosphate	triphosphate	NOUN
fnp-3528	768	31	binding	bind	VERB
fnp-3528	768	32	cassette	cassette	NOUN
fnp-3528	768	33	transporter	transporter	NOUN
fnp-3528	768	34	a1	a1	NOUN
fnp-3528	768	35	.	.	PUNCT
fnp-3528	769	1	curr	curr	PROPN
fnp-3528	769	2	opin	opin	NOUN
fnp-3528	769	3	lipidol	lipidol	ADJ
fnp-3528	769	4	2021	2021	NUM
fnp-3528	769	5	.	.	PUNCT
fnp-3528	770	1	hirsch	hirsch	PROPN
fnp-3528	770	2	-	-	PUNCT
fnp-3528	770	3	reinshagen	reinshagen	PROPN
fnp-3528	770	4	,	,	PUNCT
fnp-3528	770	5	v.	v.	ADV
fnp-3528	770	6	;	;	PUNCT
fnp-3528	770	7	zhou	zhou	PROPN
fnp-3528	770	8	,	,	PUNCT
fnp-3528	770	9	s.	s.	PROPN
fnp-3528	770	10	;	;	PUNCT
fnp-3528	770	11	burgess	burgess	PROPN
fnp-3528	770	12	,	,	PUNCT
fnp-3528	770	13	b.	b.	PROPN
fnp-3528	770	14	l.	l.	PROPN
fnp-3528	770	15	;	;	PUNCT
fnp-3528	770	16	bernier	bernier	NOUN
fnp-3528	770	17	,	,	PUNCT
fnp-3528	770	18	l.	l.	PROPN
fnp-3528	770	19	;	;	PUNCT
fnp-3528	770	20	mcisaac	mcisaac	PROPN
fnp-3528	770	21	,	,	PUNCT
fnp-3528	770	22	s.	s.	PROPN
fnp-3528	770	23	a.	a.	PROPN
fnp-3528	770	24	;	;	PUNCT
fnp-3528	770	25	chan	chan	PROPN
fnp-3528	770	26	,	,	PUNCT
fnp-3528	770	27	j.	j.	PROPN
fnp-3528	770	28	y.	y.	PROPN
fnp-3528	770	29	;	;	PUNCT
fnp-3528	770	30	tansley	tansley	NOUN
fnp-3528	770	31	,	,	PUNCT
fnp-3528	770	32	g.	g.	PROPN
fnp-3528	770	33	h.	h.	PROPN
fnp-3528	770	34	;	;	PUNCT
fnp-3528	770	35	cohn	cohn	PROPN
fnp-3528	770	36	,	,	PUNCT
fnp-3528	770	37	j.	j.	PROPN
fnp-3528	770	38	s.	s.	PROPN
fnp-3528	770	39	;	;	PUNCT
fnp-3528	770	40	hayden	hayden	PROPN
fnp-3528	770	41	,	,	PUNCT
fnp-3528	770	42	m.	m.	PROPN
fnp-3528	770	43	r.	r.	PROPN
fnp-3528	770	44	;	;	PUNCT
fnp-3528	770	45	wellington	wellington	PROPN
fnp-3528	770	46	,	,	PUNCT
fnp-3528	770	47	c.	c.	PROPN
fnp-3528	770	48	l.	l.	PROPN
fnp-3528	770	49	deficiency	deficiency	NOUN
fnp-3528	770	50	of	of	ADP
fnp-3528	770	51	abca1	abca1	NOUN
fnp-3528	770	52	impairs	impair	VERB
fnp-3528	770	53	apolipoprotein	apolipoprotein	ADJ
fnp-3528	770	54	e	e	VERB
fnp-3528	770	55	metabolism	metabolism	NOUN
fnp-3528	770	56	in	in	ADP
fnp-3528	770	57	brain	brain	NOUN
fnp-3528	770	58	.	.	PUNCT
fnp-3528	771	1	j	j	PROPN
fnp-3528	771	2	biol	biol	PROPN
fnp-3528	771	3	chem	chem	NOUN
fnp-3528	771	4	2004	2004	NUM
fnp-3528	771	5	,	,	PUNCT
fnp-3528	771	6	279	279	NUM
fnp-3528	771	7	,	,	PUNCT
fnp-3528	771	8	41197	41197	NUM
fnp-3528	771	9	-	-	SYM
fnp-3528	771	10	207	207	NUM
fnp-3528	771	11	.	.	PUNCT
fnp-3528	772	1	wahrle	wahrle	NOUN
fnp-3528	772	2	,	,	PUNCT
fnp-3528	772	3	s.	s.	PROPN
fnp-3528	772	4	e.	e.	PROPN
fnp-3528	772	5	;	;	PUNCT
fnp-3528	772	6	jiang	jiang	PROPN
fnp-3528	772	7	,	,	PUNCT
fnp-3528	772	8	h.	h.	PROPN
fnp-3528	772	9	;	;	PUNCT
fnp-3528	772	10	parsadanian	parsadanian	ADJ
fnp-3528	772	11	,	,	PUNCT
fnp-3528	772	12	m.	m.	NOUN
fnp-3528	772	13	;	;	PUNCT
fnp-3528	772	14	legleiter	legleiter	PROPN
fnp-3528	772	15	,	,	PUNCT
fnp-3528	772	16	j.	j.	PROPN
fnp-3528	772	17	;	;	PUNCT
fnp-3528	772	18	han	han	PROPN
fnp-3528	772	19	,	,	PUNCT
fnp-3528	772	20	x.	x.	NOUN
fnp-3528	772	21	;	;	PUNCT
fnp-3528	772	22	fryer	fryer	NOUN
fnp-3528	772	23	,	,	PUNCT
fnp-3528	772	24	j.	j.	PROPN
fnp-3528	772	25	d.	d.	PROPN
fnp-3528	772	26	;	;	PUNCT
fnp-3528	772	27	kowalewski	kowalewski	PROPN
fnp-3528	772	28	,	,	PUNCT
fnp-3528	772	29	t.	t.	PROPN
fnp-3528	772	30	;	;	PUNCT
fnp-3528	772	31	holtzman	holtzman	PROPN
fnp-3528	772	32	,	,	PUNCT
fnp-3528	772	33	d.	d.	PROPN
fnp-3528	772	34	m.	m.	PROPN
fnp-3528	772	35	abca1	abca1	PROPN
fnp-3528	772	36	is	be	AUX
fnp-3528	772	37	required	require	VERB
fnp-3528	772	38	for	for	ADP
fnp-3528	772	39	normal	normal	ADJ
fnp-3528	772	40	central	central	ADJ
fnp-3528	772	41	nervous	nervous	ADJ
fnp-3528	772	42	system	system	NOUN
fnp-3528	772	43	apoe	apoe	NOUN
fnp-3528	772	44	levels	level	NOUN
fnp-3528	772	45	and	and	CCONJ
fnp-3528	772	46	for	for	ADP
fnp-3528	772	47	lipidation	lipidation	NOUN
fnp-3528	772	48	of	of	ADP
fnp-3528	772	49	astrocyte	astrocyte	NOUN
fnp-3528	772	50	-	-	PUNCT
fnp-3528	772	51	secreted	secrete	VERB
fnp-3528	772	52	apoe	apoe	NOUN
fnp-3528	772	53	.	.	PUNCT
fnp-3528	773	1	j	j	PROPN
fnp-3528	773	2	biol	biol	PROPN
fnp-3528	773	3	chem	chem	NOUN
fnp-3528	773	4	2004	2004	NUM
fnp-3528	773	5	,	,	PUNCT
fnp-3528	773	6	279	279	NUM
fnp-3528	773	7	,	,	PUNCT
fnp-3528	773	8	40987	40987	NUM
fnp-3528	773	9	-	-	SYM
fnp-3528	773	10	93	93	NUM
fnp-3528	773	11	.	.	PUNCT
fnp-3528	774	1	fitz	fitz	PROPN
fnp-3528	774	2	,	,	PUNCT
fnp-3528	774	3	n.	n.	PROPN
fnp-3528	774	4	f.	f.	PROPN
fnp-3528	774	5	;	;	PUNCT
fnp-3528	774	6	carter	carter	PROPN
fnp-3528	774	7	,	,	PUNCT
fnp-3528	774	8	a.	a.	PROPN
fnp-3528	774	9	y.	y.	PROPN
fnp-3528	774	10	;	;	PUNCT
fnp-3528	774	11	tapias	tapia	NOUN
fnp-3528	774	12	,	,	PUNCT
fnp-3528	774	13	v.	v.	PROPN
fnp-3528	774	14	;	;	PUNCT
fnp-3528	774	15	castranio	castranio	PROPN
fnp-3528	774	16	,	,	PUNCT
fnp-3528	774	17	e.	e.	PROPN
fnp-3528	774	18	l.	l.	PROPN
fnp-3528	774	19	;	;	PUNCT
fnp-3528	774	20	kodali	kodali	PROPN
fnp-3528	774	21	,	,	PUNCT
fnp-3528	774	22	r.	r.	PROPN
fnp-3528	774	23	;	;	PUNCT
fnp-3528	774	24	lefterov	lefterov	PROPN
fnp-3528	774	25	,	,	PUNCT
fnp-3528	774	26	i.	i.	NOUN
fnp-3528	774	27	;	;	PUNCT
fnp-3528	774	28	koldamova	koldamova	PROPN
fnp-3528	774	29	,	,	PUNCT
fnp-3528	774	30	r.	r.	PROPN
fnp-3528	774	31	abca1	abca1	PROPN
fnp-3528	774	32	deficiency	deficiency	NOUN
fnp-3528	774	33	affects	affect	VERB
fnp-3528	774	34	basal	basal	VERB
fnp-3528	774	35	cognitive	cognitive	ADJ
fnp-3528	774	36	deficits	deficit	NOUN
fnp-3528	774	37	and	and	CCONJ
fnp-3528	774	38	dendritic	dendritic	ADJ
fnp-3528	774	39	density	density	NOUN
fnp-3528	774	40	in	in	ADP
fnp-3528	774	41	mice	mouse	NOUN
fnp-3528	774	42	.	.	PUNCT
fnp-3528	775	1	j	j	PROPN
fnp-3528	775	2	alzheimers	alzheimers	PROPN
fnp-3528	775	3	dis	dis	PROPN
fnp-3528	775	4	2017	2017	NUM
fnp-3528	775	5	,	,	PUNCT
fnp-3528	775	6	56	56	NUM
fnp-3528	775	7	,	,	PUNCT
fnp-3528	775	8	1075	1075	NUM
fnp-3528	775	9	-	-	SYM
fnp-3528	775	10	85	85	NUM
fnp-3528	775	11	.	.	PUNCT
fnp-3528	775	12	corder	corder	PROPN
fnp-3528	775	13	,	,	PUNCT
fnp-3528	775	14	e.	e.	PROPN
fnp-3528	775	15	h.	h.	PROPN
fnp-3528	775	16	;	;	PUNCT
fnp-3528	775	17	saunders	saunder	NOUN
fnp-3528	775	18	,	,	PUNCT
fnp-3528	775	19	a.	a.	NOUN
fnp-3528	775	20	m.	m.	NOUN
fnp-3528	775	21	;	;	PUNCT
fnp-3528	775	22	strittmatter	strittmatter	NOUN
fnp-3528	775	23	,	,	PUNCT
fnp-3528	775	24	w.	w.	PROPN
fnp-3528	775	25	j.	j.	PROPN
fnp-3528	775	26	;	;	PUNCT
fnp-3528	775	27	schmechel	schmechel	PROPN
fnp-3528	775	28	,	,	PUNCT
fnp-3528	775	29	d.	d.	PROPN
fnp-3528	775	30	e.	e.	PROPN
fnp-3528	775	31	;	;	PUNCT
fnp-3528	775	32	gaskell	gaskell	PROPN
fnp-3528	775	33	,	,	PUNCT
fnp-3528	775	34	p.	p.	PROPN
fnp-3528	775	35	c.	c.	PROPN
fnp-3528	775	36	;	;	PUNCT
fnp-3528	775	37	small	small	ADJ
fnp-3528	775	38	,	,	PUNCT
fnp-3528	775	39	g.	g.	PROPN
fnp-3528	775	40	w.	w.	PROPN
fnp-3528	775	41	;	;	PUNCT
fnp-3528	775	42	roses	rose	NOUN
fnp-3528	775	43	,	,	PUNCT
fnp-3528	775	44	a.	a.	PROPN
fnp-3528	775	45	d.	d.	PROPN
fnp-3528	775	46	;	;	PUNCT
fnp-3528	775	47	haines	haine	NOUN
fnp-3528	775	48	,	,	PUNCT
fnp-3528	775	49	j.	j.	PROPN
fnp-3528	775	50	l.	l.	PROPN
fnp-3528	775	51	;	;	PUNCT
fnp-3528	775	52	pericak	pericak	ADJ
fnp-3528	775	53	-	-	PUNCT
fnp-3528	775	54	vance	vance	NOUN
fnp-3528	775	55	,	,	PUNCT
fnp-3528	775	56	m.	m.	NOUN
fnp-3528	775	57	a.	a.	PROPN
fnp-3528	775	58	gene	gene	PROPN
fnp-3528	775	59	dose	dose	PROPN
fnp-3528	775	60	of	of	ADP
fnp-3528	775	61	apolipoprotein	apolipoprotein	ADJ
fnp-3528	775	62	e	e	PROPN
fnp-3528	775	63	type	type	VERB
fnp-3528	775	64	4	4	NUM
fnp-3528	775	65	allele	allele	NOUN
fnp-3528	775	66	and	and	CCONJ
fnp-3528	775	67	the	the	DET
fnp-3528	775	68	risk	risk	NOUN
fnp-3528	775	69	of	of	ADP
fnp-3528	775	70	alzheimer	alzheimer	PROPN
fnp-3528	775	71	's	's	PART
fnp-3528	775	72	disease	disease	NOUN
fnp-3528	775	73	in	in	ADP
fnp-3528	775	74	late	late	ADJ
fnp-3528	775	75	onset	onset	NOUN
fnp-3528	775	76	families	family	NOUN
fnp-3528	775	77	.	.	PUNCT
fnp-3528	776	1	science	science	NOUN
fnp-3528	776	2	1993	1993	NUM
fnp-3528	776	3	,	,	PUNCT
fnp-3528	776	4	261	261	NUM
fnp-3528	776	5	,	,	PUNCT
fnp-3528	776	6	921	921	NUM
fnp-3528	776	7	-	-	SYM
fnp-3528	776	8	3	3	NUM
fnp-3528	776	9	.	.	PUNCT
fnp-3528	776	10	poirier	poirier	PROPN
fnp-3528	776	11	,	,	PUNCT
fnp-3528	776	12	j.	j.	PROPN
fnp-3528	776	13	;	;	PUNCT
fnp-3528	776	14	davignon	davignon	PROPN
fnp-3528	776	15	,	,	PUNCT
fnp-3528	776	16	j.	j.	PROPN
fnp-3528	776	17	;	;	PUNCT
fnp-3528	776	18	bouthillier	bouthillier	NOUN
fnp-3528	776	19	,	,	PUNCT
fnp-3528	776	20	d.	d.	PROPN
fnp-3528	776	21	;	;	PUNCT
fnp-3528	776	22	kogan	kogan	PROPN
fnp-3528	776	23	,	,	PUNCT
fnp-3528	776	24	s.	s.	PROPN
fnp-3528	776	25	;	;	PUNCT
fnp-3528	776	26	bertrand	bertrand	PROPN
fnp-3528	776	27	,	,	PUNCT
fnp-3528	776	28	p.	p.	PROPN
fnp-3528	776	29	;	;	PUNCT
fnp-3528	776	30	gauthier	gauthier	PROPN
fnp-3528	776	31	,	,	PUNCT
fnp-3528	776	32	s.	s.	PROPN
fnp-3528	776	33	apolipoprotein	apolipoprotein	VERB
fnp-3528	776	34	e	e	PROPN
fnp-3528	776	35	polymorphism	polymorphism	NOUN
fnp-3528	776	36	and	and	CCONJ
fnp-3528	776	37	alzheimer	alzheimer	PROPN
fnp-3528	776	38	's	's	PART
fnp-3528	776	39	disease	disease	NOUN
fnp-3528	776	40	.	.	PUNCT
fnp-3528	777	1	lancet	lancet	PROPN
fnp-3528	777	2	1993	1993	NUM
fnp-3528	777	3	,	,	PUNCT
fnp-3528	777	4	342	342	NUM
fnp-3528	777	5	,	,	PUNCT
fnp-3528	777	6	697	697	NUM
fnp-3528	777	7	-	-	SYM
fnp-3528	777	8	9	9	NUM
fnp-3528	777	9	.	.	PUNCT
fnp-3528	777	10	rawat	rawat	PROPN
fnp-3528	777	11	,	,	PUNCT
fnp-3528	777	12	v.	v.	PROPN
fnp-3528	777	13	;	;	PUNCT
fnp-3528	777	14	wang	wang	PROPN
fnp-3528	777	15	,	,	PUNCT
fnp-3528	777	16	s.	s.	PROPN
fnp-3528	777	17	;	;	PUNCT
fnp-3528	777	18	sima	sima	PROPN
fnp-3528	777	19	,	,	PUNCT
fnp-3528	777	20	j.	j.	PROPN
fnp-3528	777	21	;	;	PUNCT
fnp-3528	777	22	bar	bar	PROPN
fnp-3528	777	23	,	,	PUNCT
fnp-3528	777	24	r.	r.	PROPN
fnp-3528	777	25	;	;	PUNCT
fnp-3528	777	26	liraz	liraz	NOUN
fnp-3528	777	27	,	,	PUNCT
fnp-3528	777	28	o.	o.	INTJ
fnp-3528	777	29	;	;	PUNCT
fnp-3528	777	30	gundimeda	gundimeda	PROPN
fnp-3528	777	31	,	,	PUNCT
fnp-3528	777	32	u.	u.	PROPN
fnp-3528	777	33	;	;	PUNCT
fnp-3528	777	34	parekh	parekh	PROPN
fnp-3528	777	35	,	,	PUNCT
fnp-3528	777	36	t.	t.	PROPN
fnp-3528	777	37	;	;	PUNCT
fnp-3528	777	38	chan	chan	PROPN
fnp-3528	777	39	,	,	PUNCT
fnp-3528	777	40	j.	j.	PROPN
fnp-3528	777	41	;	;	PUNCT
fnp-3528	777	42	johansson	johansson	PROPN
fnp-3528	777	43	,	,	PUNCT
fnp-3528	777	44	j.	j.	PROPN
fnp-3528	777	45	o.	o.	PROPN
fnp-3528	777	46	;	;	PUNCT
fnp-3528	777	47	tang	tang	PROPN
fnp-3528	777	48	,	,	PUNCT
fnp-3528	777	49	c.	c.	PROPN
fnp-3528	777	50	;	;	PUNCT
fnp-3528	777	51	chui	chui	PROPN
fnp-3528	777	52	,	,	PUNCT
fnp-3528	777	53	h.	h.	PROPN
fnp-3528	777	54	c.	c.	PROPN
fnp-3528	777	55	;	;	PUNCT
fnp-3528	777	56	harrington	harrington	PROPN
fnp-3528	777	57	,	,	PUNCT
fnp-3528	777	58	m.	m.	NOUN
fnp-3528	777	59	g.	g.	PROPN
fnp-3528	777	60	;	;	PUNCT
fnp-3528	777	61	michaelson	michaelson	PROPN
fnp-3528	777	62	,	,	PUNCT
fnp-3528	777	63	d.	d.	PROPN
fnp-3528	777	64	m.	m.	PROPN
fnp-3528	777	65	;	;	PUNCT
fnp-3528	777	66	yassine	yassine	PROPN
fnp-3528	777	67	,	,	PUNCT
fnp-3528	777	68	h.	h.	PROPN
fnp-3528	777	69	n.	n.	PROPN
fnp-3528	777	70	apoe4	apoe4	PROPN
fnp-3528	777	71	alters	alter	VERB
fnp-3528	777	72	abca1	abca1	NOUN
fnp-3528	777	73	membrane	membrane	NOUN
fnp-3528	777	74	trafficking	trafficking	NOUN
fnp-3528	777	75	in	in	ADP
fnp-3528	777	76	astrocytes	astrocyte	NOUN
fnp-3528	777	77	.	.	PUNCT
fnp-3528	778	1	j	j	PROPN
fnp-3528	778	2	neurosci	neurosci	PROPN
fnp-3528	778	3	2019	2019	NUM
fnp-3528	778	4	,	,	PUNCT
fnp-3528	778	5	39	39	NUM
fnp-3528	778	6	,	,	PUNCT
fnp-3528	778	7	9611	9611	NUM
fnp-3528	778	8	-	-	SYM
fnp-3528	778	9	22	22	NUM
fnp-3528	778	10	.	.	PUNCT
fnp-3528	779	1	marchi	marchi	PROPN
fnp-3528	779	2	,	,	PUNCT
fnp-3528	779	3	c.	c.	PROPN
fnp-3528	779	4	;	;	PUNCT
fnp-3528	779	5	adorni	adorni	PROPN
fnp-3528	779	6	,	,	PUNCT
fnp-3528	779	7	m.	m.	NOUN
fnp-3528	779	8	p.	p.	NOUN
fnp-3528	779	9	;	;	PUNCT
fnp-3528	779	10	caffarra	caffarra	VERB
fnp-3528	779	11	,	,	PUNCT
fnp-3528	779	12	p.	p.	PROPN
fnp-3528	779	13	;	;	PUNCT
fnp-3528	779	14	ronda	ronda	PROPN
fnp-3528	779	15	,	,	PUNCT
fnp-3528	779	16	n.	n.	NOUN
fnp-3528	779	17	;	;	PUNCT
fnp-3528	779	18	spallazzi	spallazzi	NOUN
fnp-3528	779	19	,	,	PUNCT
fnp-3528	779	20	m.	m.	NOUN
fnp-3528	779	21	;	;	PUNCT
fnp-3528	779	22	barocco	barocco	PROPN
fnp-3528	779	23	,	,	PUNCT
fnp-3528	779	24	f.	f.	PROPN
fnp-3528	779	25	;	;	PUNCT
fnp-3528	779	26	galimberti	galimberti	PROPN
fnp-3528	779	27	,	,	PUNCT
fnp-3528	779	28	d.	d.	PROPN
fnp-3528	779	29	;	;	PUNCT
fnp-3528	779	30	bernini	bernini	PROPN
fnp-3528	779	31	,	,	PUNCT
fnp-3528	779	32	f.	f.	PROPN
fnp-3528	779	33	;	;	PUNCT
fnp-3528	779	34	zimetti	zimetti	PROPN
fnp-3528	779	35	,	,	PUNCT
fnp-3528	779	36	f.	f.	PROPN
fnp-3528	779	37	abca1and	abca1and	ADP
fnp-3528	779	38	abcg1	abcg1	ADV
fnp-3528	779	39	-	-	PUNCT
fnp-3528	779	40	mediated	mediate	VERB
fnp-3528	779	41	cholesterol	cholesterol	NOUN
fnp-3528	779	42	efflux	efflux	NOUN
fnp-3528	779	43	capacity	capacity	NOUN
fnp-3528	779	44	of	of	ADP
fnp-3528	779	45	cerebrospinal	cerebrospinal	ADJ
fnp-3528	779	46	fluid	fluid	NOUN
fnp-3528	779	47	is	be	AUX
fnp-3528	779	48	impaired	impair	VERB
fnp-3528	779	49	in	in	ADP
fnp-3528	779	50	alzheimer	alzheimer	PROPN
fnp-3528	779	51	's	's	PART
fnp-3528	779	52	disease	disease	NOUN
fnp-3528	779	53	.	.	PUNCT
fnp-3528	780	1	j	j	PROPN
fnp-3528	780	2	lipid	lipid	PROPN
fnp-3528	780	3	res	re	VERB
fnp-3528	780	4	2019	2019	NUM
fnp-3528	780	5	,	,	PUNCT
fnp-3528	780	6	60	60	NUM
fnp-3528	780	7	,	,	PUNCT
fnp-3528	780	8	1449	1449	NUM
fnp-3528	780	9	-	-	SYM
fnp-3528	780	10	56	56	NUM
fnp-3528	780	11	.	.	PUNCT
fnp-3528	781	1	akram	akram	PROPN
fnp-3528	781	2	,	,	PUNCT
fnp-3528	781	3	a.	a.	NOUN
fnp-3528	781	4	;	;	PUNCT
fnp-3528	781	5	schmeidler	schmeidler	NOUN
fnp-3528	781	6	,	,	PUNCT
fnp-3528	781	7	j.	j.	PROPN
fnp-3528	781	8	;	;	PUNCT
fnp-3528	781	9	katsel	katsel	ADJ
fnp-3528	781	10	,	,	PUNCT
fnp-3528	781	11	p.	p.	NOUN
fnp-3528	781	12	;	;	PUNCT
fnp-3528	781	13	hof	hof	PROPN
fnp-3528	781	14	,	,	PUNCT
fnp-3528	781	15	p.	p.	PROPN
fnp-3528	781	16	r.	r.	PROPN
fnp-3528	781	17	;	;	PUNCT
fnp-3528	781	18	haroutunian	haroutunian	ADJ
fnp-3528	781	19	,	,	PUNCT
fnp-3528	781	20	v.	v.	ADP
fnp-3528	781	21	increased	increase	VERB
fnp-3528	781	22	expression	expression	NOUN
fnp-3528	781	23	of	of	ADP
fnp-3528	781	24	cholesterol	cholesterol	NOUN
fnp-3528	781	25	transporter	transporter	NOUN
fnp-3528	781	26	abca1	abca1	NOUN
fnp-3528	781	27	is	be	AUX
fnp-3528	781	28	highly	highly	ADV
fnp-3528	781	29	correlated	correlate	VERB
fnp-3528	781	30	with	with	ADP
fnp-3528	781	31	severity	severity	NOUN
fnp-3528	781	32	of	of	ADP
fnp-3528	781	33	dementia	dementia	NOUN
fnp-3528	781	34	in	in	ADP
fnp-3528	781	35	ad	ad	NOUN
fnp-3528	781	36	hippocampus	hippocampus	NOUN
fnp-3528	781	37	.	.	PUNCT
fnp-3528	782	1	brain	brain	NOUN
fnp-3528	782	2	res	re	NOUN
fnp-3528	782	3	2010	2010	NUM
fnp-3528	782	4	,	,	PUNCT
fnp-3528	782	5	1318	1318	NUM
fnp-3528	782	6	,	,	PUNCT
fnp-3528	782	7	167	167	NUM
fnp-3528	782	8	-	-	SYM
fnp-3528	782	9	77	77	NUM
fnp-3528	782	10	.	.	PUNCT
fnp-3528	783	1	holstege	holstege	PROPN
fnp-3528	783	2	,	,	PUNCT
fnp-3528	783	3	h.	h.	PROPN
fnp-3528	783	4	;	;	PUNCT
fnp-3528	783	5	hulsman	hulsman	PROPN
fnp-3528	783	6	,	,	PUNCT
fnp-3528	783	7	m.	m.	NOUN
fnp-3528	783	8	;	;	PUNCT
fnp-3528	783	9	charbonnier	charbonnier	NOUN
fnp-3528	783	10	,	,	PUNCT
fnp-3528	783	11	c.	c.	PROPN
fnp-3528	783	12	;	;	PUNCT
fnp-3528	783	13	grenier	grenier	NOUN
fnp-3528	783	14	-	-	PUNCT
fnp-3528	783	15	boley	boley	PROPN
fnp-3528	783	16	,	,	PUNCT
fnp-3528	783	17	b.	b.	PROPN
fnp-3528	783	18	;	;	PUNCT
fnp-3528	783	19	quenez	quenez	PROPN
fnp-3528	783	20	,	,	PUNCT
fnp-3528	783	21	o.	o.	PROPN
fnp-3528	783	22	;	;	PUNCT
fnp-3528	783	23	grozeva	grozeva	VERB
fnp-3528	783	24	,	,	PUNCT
fnp-3528	783	25	d.	d.	PROPN
fnp-3528	783	26	;	;	PUNCT
fnp-3528	783	27	van	van	PROPN
fnp-3528	783	28	rooij	rooij	PROPN
fnp-3528	783	29	,	,	PUNCT
fnp-3528	783	30	j.	j.	PROPN
fnp-3528	783	31	g.	g.	PROPN
fnp-3528	783	32	j.	j.	PROPN
fnp-3528	783	33	;	;	PUNCT
fnp-3528	783	34	sims	sim	NOUN
fnp-3528	783	35	,	,	PUNCT
fnp-3528	783	36	r.	r.	PROPN
fnp-3528	783	37	;	;	PUNCT
fnp-3528	783	38	ahmad	ahmad	PROPN
fnp-3528	783	39	,	,	PUNCT
fnp-3528	783	40	s.	s.	PROPN
fnp-3528	783	41	;	;	PUNCT
fnp-3528	783	42	amin	amin	PROPN
fnp-3528	783	43	,	,	PUNCT
fnp-3528	783	44	n.	n.	NOUN
fnp-3528	783	45	;	;	PUNCT
fnp-3528	783	46	norsworthy	norsworthy	ADJ
fnp-3528	783	47	,	,	PUNCT
fnp-3528	783	48	p.	p.	PROPN
fnp-3528	783	49	j.	j.	PROPN
fnp-3528	783	50	;	;	PUNCT
fnp-3528	783	51	dols	dol	NOUN
fnp-3528	783	52	-	-	PUNCT
fnp-3528	783	53	icardo	icardo	NOUN
fnp-3528	783	54	,	,	PUNCT
fnp-3528	783	55	o.	o.	PROPN
fnp-3528	783	56	;	;	PUNCT
fnp-3528	783	57	hummerich	hummerich	PROPN
fnp-3528	783	58	,	,	PUNCT
fnp-3528	783	59	h.	h.	PROPN
fnp-3528	783	60	;	;	PUNCT
fnp-3528	783	61	kawalia	kawalia	PROPN
fnp-3528	783	62	,	,	PUNCT
fnp-3528	783	63	a.	a.	NOUN
fnp-3528	783	64	;	;	PUNCT
fnp-3528	783	65	database	database	NOUN
fnp-3528	783	66	,	,	PUNCT
fnp-3528	783	67	a.	a.	PROPN
fnp-3528	783	68	s.	s.	PROPN
fnp-3528	783	69	d.	d.	PROPN
fnp-3528	783	70	n.	n.	PROPN
fnp-3528	783	71	i.	i.	PROPN
fnp-3528	783	72	;	;	PUNCT
fnp-3528	783	73	amouyel	amouyel	PROPN
fnp-3528	783	74	,	,	PUNCT
fnp-3528	783	75	p.	p.	PROPN
fnp-3528	783	76	;	;	PUNCT
fnp-3528	783	77	beecham	beecham	PROPN
fnp-3528	783	78	,	,	PUNCT
fnp-3528	783	79	g.	g.	PROPN
fnp-3528	783	80	w.	w.	PROPN
fnp-3528	783	81	;	;	PUNCT
fnp-3528	783	82	berr	berr	PROPN
fnp-3528	783	83	,	,	PUNCT
fnp-3528	783	84	c.	c.	PROPN
fnp-3528	783	85	;	;	PUNCT
fnp-3528	783	86	bis	bis	PROPN
fnp-3528	783	87	,	,	PUNCT
fnp-3528	783	88	j.	j.	PROPN
fnp-3528	783	89	c.	c.	PROPN
fnp-3528	783	90	;	;	PUNCT
fnp-3528	783	91	boland	boland	PROPN
fnp-3528	783	92	,	,	PUNCT
fnp-3528	783	93	a.	a.	NOUN
fnp-3528	783	94	;	;	PUNCT
fnp-3528	783	95	bossù	bossù	PROPN
fnp-3528	783	96	,	,	PUNCT
fnp-3528	783	97	p.	p.	PROPN
fnp-3528	783	98	;	;	PUNCT
fnp-3528	783	99	bouwman	bouwman	PROPN
fnp-3528	783	100	,	,	PUNCT
fnp-3528	783	101	f.	f.	PROPN
fnp-3528	783	102	;	;	PUNCT
fnp-3528	783	103	bras	bras	PROPN
fnp-3528	783	104	,	,	PUNCT
fnp-3528	783	105	j.	j.	PROPN
fnp-3528	783	106	;	;	PUNCT
fnp-3528	783	107	campion	campion	PROPN
fnp-3528	783	108	,	,	PUNCT
fnp-3528	783	109	d.	d.	PROPN
fnp-3528	783	110	;	;	PUNCT
fnp-3528	783	111	cochran	cochran	PROPN
fnp-3528	783	112	,	,	PUNCT
fnp-3528	783	113	j.	j.	PROPN
fnp-3528	783	114	n.	n.	PROPN
fnp-3528	783	115	;	;	PUNCT
fnp-3528	783	116	daniele	daniele	PROPN
fnp-3528	783	117	,	,	PUNCT
fnp-3528	783	118	a.	a.	NOUN
fnp-3528	783	119	;	;	PUNCT
fnp-3528	783	120	dartigues	dartigue	NOUN
fnp-3528	783	121	,	,	PUNCT
fnp-3528	783	122	j.-f	j.-f	PROPN
fnp-3528	783	123	.	.	PUNCT
fnp-3528	783	124	;	;	PUNCT
fnp-3528	784	1	debette	debette	NOUN
fnp-3528	784	2	,	,	PUNCT
fnp-3528	784	3	s.	s.	PROPN
fnp-3528	784	4	;	;	PUNCT
fnp-3528	784	5	deleuze	deleuze	PROPN
fnp-3528	784	6	,	,	PUNCT
fnp-3528	784	7	j.-f	j.-f	PROPN
fnp-3528	784	8	.	.	PUNCT
fnp-3528	784	9	;	;	PUNCT
fnp-3528	784	10	denning	den	VERB
fnp-3528	784	11	,	,	PUNCT
fnp-3528	784	12	n.	n.	NOUN
fnp-3528	784	13	;	;	PUNCT
fnp-3528	784	14	destefano	destefano	NOUN
fnp-3528	784	15	,	,	PUNCT
fnp-3528	784	16	a.	a.	PROPN
fnp-3528	784	17	l.	l.	PROPN
fnp-3528	784	18	;	;	PUNCT
fnp-3528	784	19	farrer	farrer	PROPN
fnp-3528	784	20	,	,	PUNCT
fnp-3528	784	21	l.	l.	PROPN
fnp-3528	784	22	a.	a.	PROPN
fnp-3528	784	23	;	;	PUNCT
fnp-3528	784	24	fernandez	fernandez	PROPN
fnp-3528	784	25	,	,	PUNCT
fnp-3528	784	26	m.	m.	NOUN
fnp-3528	784	27	v.	v.	PROPN
fnp-3528	784	28	;	;	PUNCT
fnp-3528	784	29	fox	fox	PROPN
fnp-3528	784	30	,	,	PUNCT
fnp-3528	784	31	n.	n.	PROPN
fnp-3528	784	32	c.	c.	PROPN
fnp-3528	784	33	;	;	PUNCT
fnp-3528	784	34	galimberti	galimberti	PROPN
fnp-3528	784	35	,	,	PUNCT
fnp-3528	784	36	d.	d.	PROPN
fnp-3528	784	37	;	;	PUNCT
fnp-3528	784	38	genin	genin	PROPN
fnp-3528	784	39	,	,	PUNCT
fnp-3528	784	40	e.	e.	PROPN
fnp-3528	784	41	;	;	PUNCT
fnp-3528	784	42	gille	gille	PROPN
fnp-3528	784	43	,	,	PUNCT
fnp-3528	784	44	h.	h.	PROPN
fnp-3528	784	45	;	;	PUNCT
fnp-3528	784	46	guen	guen	PROPN
fnp-3528	784	47	,	,	PUNCT
fnp-3528	784	48	y.	y.	PROPN
fnp-3528	784	49	l.	l.	PROPN
fnp-3528	784	50	;	;	PUNCT
fnp-3528	784	51	guerreiro	guerreiro	PROPN
fnp-3528	784	52	,	,	PUNCT
fnp-3528	784	53	r.	r.	PROPN
fnp-3528	784	54	;	;	PUNCT
fnp-3528	784	55	haines	haine	NOUN
fnp-3528	784	56	,	,	PUNCT
fnp-3528	784	57	j.	j.	PROPN
fnp-3528	784	58	l.	l.	PROPN
fnp-3528	784	59	;	;	PUNCT
fnp-3528	784	60	holmes	holmes	PROPN
fnp-3528	784	61	,	,	PUNCT
fnp-3528	784	62	c.	c.	PROPN
fnp-3528	784	63	;	;	PUNCT
fnp-3528	784	64	ikram	ikram	NOUN
fnp-3528	784	65	,	,	PUNCT
fnp-3528	784	66	m.	m.	NOUN
fnp-3528	784	67	a.	a.	PROPN
fnp-3528	784	68	;	;	PUNCT
fnp-3528	784	69	ikram	ikram	NOUN
fnp-3528	784	70	,	,	PUNCT
fnp-3528	784	71	m.	m.	NOUN
fnp-3528	784	72	k.	k.	PROPN
fnp-3528	784	73	;	;	PUNCT
fnp-3528	784	74	jansen	jansen	PROPN
fnp-3528	784	75	,	,	PUNCT
fnp-3528	784	76	i.	i.	PROPN
fnp-3528	784	77	e.	e.	PROPN
fnp-3528	784	78	;	;	PUNCT
fnp-3528	784	79	kraaij	kraaij	PROPN
fnp-3528	784	80	,	,	PUNCT
fnp-3528	784	81	r.	r.	PROPN
fnp-3528	784	82	;	;	PUNCT
fnp-3528	784	83	lathrop	lathrop	PROPN
fnp-3528	784	84	,	,	PUNCT
fnp-3528	784	85	m.	m.	NOUN
fnp-3528	784	86	;	;	PUNCT
fnp-3528	784	87	lemstra	lemstra	PROPN
fnp-3528	784	88	,	,	PUNCT
fnp-3528	784	89	a.	a.	PROPN
fnp-3528	784	90	w.	w.	PROPN
fnp-3528	784	91	;	;	PUNCT
fnp-3528	784	92	lleó	lleó	PROPN
fnp-3528	784	93	,	,	PUNCT
fnp-3528	784	94	a.	a.	NOUN
fnp-3528	784	95	;	;	PUNCT
fnp-3528	784	96	luckcuck	luckcuck	NOUN
fnp-3528	784	97	,	,	PUNCT
fnp-3528	784	98	l.	l.	PROPN
fnp-3528	784	99	;	;	PUNCT
fnp-3528	784	100	mannens	mannens	PROPN
fnp-3528	784	101	,	,	PUNCT
fnp-3528	784	102	m.	m.	NOUN
fnp-3528	784	103	m.	m.	PROPN
fnp-3528	784	104	a.	a.	PROPN
fnp-3528	784	105	m.	m.	PROPN
fnp-3528	784	106	;	;	PUNCT
fnp-3528	784	107	marshall	marshall	PROPN
fnp-3528	784	108	,	,	PUNCT
fnp-3528	784	109	r.	r.	PROPN
fnp-3528	784	110	;	;	PUNCT
fnp-3528	784	111	martin	martin	PROPN
fnp-3528	784	112	,	,	PUNCT
fnp-3528	784	113	e.	e.	PROPN
fnp-3528	784	114	r.	r.	PROPN
fnp-3528	784	115	;	;	PUNCT
fnp-3528	784	116	masullo	masullo	PROPN
fnp-3528	784	117	,	,	PUNCT
fnp-3528	784	118	c.	c.	PROPN
fnp-3528	784	119	;	;	PUNCT
fnp-3528	784	120	mayeux	mayeux	PROPN
fnp-3528	784	121	,	,	PUNCT
fnp-3528	784	122	r.	r.	PROPN
fnp-3528	784	123	;	;	PUNCT
fnp-3528	784	124	mecocci	mecocci	PROPN
fnp-3528	784	125	,	,	PUNCT
fnp-3528	784	126	p.	p.	PROPN
fnp-3528	784	127	;	;	PUNCT
fnp-3528	784	128	meggy	meggy	PROPN
fnp-3528	784	129	,	,	PUNCT
fnp-3528	784	130	a.	a.	PROPN
fnp-3528	784	131	;	;	PUNCT
fnp-3528	784	132	mol	mol	PROPN
fnp-3528	784	133	,	,	PUNCT
fnp-3528	784	134	m.	m.	NOUN
fnp-3528	784	135	o.	o.	PROPN
fnp-3528	784	136	;	;	PUNCT
fnp-3528	784	137	morgan	morgan	PROPN
fnp-3528	784	138	,	,	PUNCT
fnp-3528	784	139	k.	k.	PROPN
fnp-3528	784	140	;	;	PUNCT
fnp-3528	784	141	myers	myers	PROPN
fnp-3528	784	142	,	,	PUNCT
fnp-3528	784	143	r.	r.	PROPN
fnp-3528	784	144	m.	m.	PROPN
fnp-3528	784	145	;	;	PUNCT
fnp-3528	784	146	nacmias	nacmias	PROPN
fnp-3528	784	147	,	,	PUNCT
fnp-3528	784	148	b.	b.	PROPN
fnp-3528	784	149	;	;	PUNCT
fnp-3528	784	150	naj	naj	PROPN
fnp-3528	784	151	,	,	PUNCT
fnp-3528	784	152	a.	a.	PROPN
fnp-3528	784	153	c.	c.	PROPN
fnp-3528	784	154	;	;	PUNCT
fnp-3528	784	155	napolioni	napolioni	PROPN
fnp-3528	784	156	,	,	PUNCT
fnp-3528	784	157	v.	v.	PROPN
fnp-3528	784	158	;	;	PUNCT
fnp-3528	784	159	pasquier	pasquier	PROPN
fnp-3528	784	160	,	,	PUNCT
fnp-3528	784	161	f.	f.	PROPN
fnp-3528	784	162	;	;	PUNCT
fnp-3528	784	163	pastor	pastor	NOUN
fnp-3528	784	164	,	,	PUNCT
fnp-3528	784	165	p.	p.	NOUN
fnp-3528	784	166	;	;	PUNCT
fnp-3528	784	167	pericak	pericak	ADJ
fnp-3528	784	168	-	-	PUNCT
fnp-3528	784	169	vance	vance	NOUN
fnp-3528	784	170	,	,	PUNCT
fnp-3528	784	171	m.	m.	NOUN
fnp-3528	784	172	a.	a.	PROPN
fnp-3528	784	173	;	;	PUNCT
fnp-3528	784	174	raybould	raybould	AUX
fnp-3528	784	175	,	,	PUNCT
fnp-3528	784	176	r.	r.	PROPN
fnp-3528	784	177	;	;	PUNCT
fnp-3528	784	178	redon	redon	PROPN
fnp-3528	784	179	,	,	PUNCT
fnp-3528	784	180	r.	r.	PROPN
fnp-3528	784	181	;	;	PUNCT
fnp-3528	784	182	reinders	reinder	NOUN
fnp-3528	784	183	,	,	PUNCT
fnp-3528	784	184	m.	m.	NOUN
fnp-3528	784	185	j.	j.	PROPN
fnp-3528	784	186	t.	t.	PROPN
fnp-3528	784	187	;	;	PUNCT
fnp-3528	784	188	richard	richard	PROPN
fnp-3528	784	189	,	,	PUNCT
fnp-3528	784	190	a.-c	a.-c	PROPN
fnp-3528	784	191	.	.	PUNCT
fnp-3528	784	192	;	;	PUNCT
fnp-3528	784	193	riedel	riedel	NOUN
fnp-3528	784	194	-	-	PUNCT
fnp-3528	784	195	heller	heller	NOUN
fnp-3528	784	196	,	,	PUNCT
fnp-3528	784	197	s.	s.	PROPN
fnp-3528	784	198	g.	g.	PROPN
fnp-3528	784	199	;	;	PUNCT
fnp-3528	784	200	rivadeneira	rivadeneira	PROPN
fnp-3528	784	201	,	,	PUNCT
fnp-3528	784	202	f.	f.	PROPN
fnp-3528	784	203	;	;	PUNCT
fnp-3528	784	204	rousseau	rousseau	PROPN
fnp-3528	784	205	,	,	PUNCT
fnp-3528	784	206	s.	s.	PROPN
fnp-3528	784	207	;	;	PUNCT
fnp-3528	784	208	ryan	ryan	PROPN
fnp-3528	784	209	,	,	PUNCT
fnp-3528	784	210	n.	n.	PROPN
fnp-3528	784	211	s.	s.	PROPN
fnp-3528	784	212	;	;	PUNCT
fnp-3528	784	213	saad	saad	PROPN
fnp-3528	784	214	,	,	PUNCT
fnp-3528	784	215	s.	s.	PROPN
fnp-3528	784	216	;	;	PUNCT
fnp-3528	784	217	sanchez	sanchez	PROPN
fnp-3528	784	218	-	-	PUNCT
fnp-3528	784	219	juan	juan	PROPN
fnp-3528	784	220	,	,	PUNCT
fnp-3528	784	221	p.	p.	PROPN
fnp-3528	784	222	;	;	PUNCT
fnp-3528	784	223	schellenberg	schellenberg	PROPN
fnp-3528	784	224	,	,	PUNCT
fnp-3528	784	225	g.	g.	PROPN
fnp-3528	784	226	d.	d.	PROPN
fnp-3528	784	227	;	;	PUNCT
fnp-3528	784	228	scheltens	schelten	NOUN
fnp-3528	784	229	,	,	PUNCT
fnp-3528	784	230	p.	p.	NOUN
fnp-3528	784	231	;	;	PUNCT
fnp-3528	784	232	schott	schott	PROPN
fnp-3528	784	233	,	,	PUNCT
fnp-3528	784	234	j.	j.	PROPN
fnp-3528	784	235	m.	m.	PROPN
fnp-3528	784	236	;	;	PUNCT
fnp-3528	784	237	seripa	seripa	PROPN
fnp-3528	784	238	,	,	PUNCT
fnp-3528	784	239	d.	d.	PROPN
fnp-3528	784	240	;	;	PUNCT
fnp-3528	784	241	seshadri	seshadri	PROPN
fnp-3528	784	242	,	,	PUNCT
fnp-3528	784	243	s.	s.	PROPN
fnp-3528	784	244	;	;	PUNCT
fnp-3528	784	245	sie	sie	PROPN
fnp-3528	784	246	,	,	PUNCT
fnp-3528	784	247	d.	d.	PROPN
fnp-3528	784	248	;	;	PUNCT
fnp-3528	784	249	sistermans	sisterman	NOUN
fnp-3528	784	250	,	,	PUNCT
fnp-3528	784	251	e.	e.	PROPN
fnp-3528	784	252	;	;	PUNCT
fnp-3528	784	253	sorbi	sorbi	PROPN
fnp-3528	784	254	,	,	PUNCT
fnp-3528	784	255	s.	s.	PROPN
fnp-3528	784	256	;	;	PUNCT
fnp-3528	784	257	van	van	PROPN
fnp-3528	784	258	spaendonk	spaendonk	NOUN
fnp-3528	784	259	,	,	PUNCT
fnp-3528	784	260	r.	r.	PROPN
fnp-3528	784	261	;	;	PUNCT
fnp-3528	784	262	spalletta	spalletta	PROPN
fnp-3528	784	263	,	,	PUNCT
fnp-3528	784	264	g.	g.	PROPN
fnp-3528	784	265	;	;	PUNCT
fnp-3528	784	266	tesi	tesi	PROPN
fnp-3528	784	267	,	,	PUNCT
fnp-3528	784	268	n.	n.	NOUN
fnp-3528	784	269	;	;	PUNCT
fnp-3528	784	270	tijms	tijms	PROPN
fnp-3528	784	271	,	,	PUNCT
fnp-3528	784	272	b.	b.	PROPN
fnp-3528	784	273	;	;	PUNCT
fnp-3528	784	274	uitterlinden	uitterlinden	ADJ
fnp-3528	784	275	,	,	PUNCT
fnp-3528	784	276	a.	a.	NOUN
fnp-3528	784	277	g.	g.	PROPN
fnp-3528	784	278	;	;	PUNCT
fnp-3528	784	279	van	van	PROPN
fnp-3528	784	280	der	der	PROPN
fnp-3528	784	281	lee	lee	PROPN
fnp-3528	784	282	,	,	PUNCT
fnp-3528	784	283	s.	s.	PROPN
fnp-3528	784	284	j.	j.	PROPN
fnp-3528	784	285	;	;	PUNCT
fnp-3528	784	286	de	de	PROPN
fnp-3528	784	287	visser	visser	PROPN
fnp-3528	784	288	,	,	PUNCT
fnp-3528	784	289	p.	p.	PROPN
fnp-3528	784	290	j.	j.	PROPN
fnp-3528	784	291	;	;	PUNCT
fnp-3528	784	292	wagner	wagner	PROPN
fnp-3528	784	293	,	,	PUNCT
fnp-3528	784	294	m.	m.	NOUN
fnp-3528	784	295	;	;	PUNCT
fnp-3528	784	296	wallon	wallon	PROPN
fnp-3528	784	297	,	,	PUNCT
fnp-3528	784	298	d.	d.	PROPN
fnp-3528	784	299	;	;	PUNCT
fnp-3528	784	300	wang	wang	PROPN
fnp-3528	784	301	,	,	PUNCT
fnp-3528	784	302	l.-s	l.-s	PROPN
fnp-3528	784	303	.	.	PUNCT
fnp-3528	784	304	;	;	PUNCT
fnp-3528	785	1	zarea	zarea	PROPN
fnp-3528	785	2	,	,	PUNCT
fnp-3528	785	3	a.	a.	NOUN
fnp-3528	785	4	;	;	PUNCT
fnp-3528	785	5	clarimon	clarimon	NOUN
fnp-3528	785	6	,	,	PUNCT
fnp-3528	785	7	j.	j.	PROPN
fnp-3528	785	8	;	;	PUNCT
fnp-3528	785	9	van	van	PROPN
fnp-3528	785	10	swieten	swieten	PROPN
fnp-3528	785	11	,	,	PUNCT
fnp-3528	785	12	j.	j.	PROPN
fnp-3528	785	13	c.	c.	PROPN
fnp-3528	785	14	;	;	PUNCT
fnp-3528	785	15	greicius	greicius	NOUN
fnp-3528	785	16	,	,	PUNCT
fnp-3528	785	17	m.	m.	NOUN
fnp-3528	785	18	d.	d.	PROPN
fnp-3528	785	19	;	;	PUNCT
fnp-3528	785	20	yokoyama	yokoyama	PROPN
fnp-3528	785	21	,	,	PUNCT
fnp-3528	785	22	j.	j.	PROPN
fnp-3528	785	23	s.	s.	PROPN
fnp-3528	785	24	;	;	PUNCT
fnp-3528	785	25	cruchaga	cruchaga	NOUN
fnp-3528	785	26	,	,	PUNCT
fnp-3528	785	27	c.	c.	PROPN
fnp-3528	785	28	;	;	PUNCT
fnp-3528	785	29	hardy	hardy	ADJ
fnp-3528	785	30	,	,	PUNCT
fnp-3528	785	31	j.	j.	PROPN
fnp-3528	785	32	;	;	PUNCT
fnp-3528	785	33	ramirez	ramirez	PROPN
fnp-3528	785	34	,	,	PUNCT
fnp-3528	785	35	a.	a.	NOUN
fnp-3528	785	36	;	;	PUNCT
fnp-3528	785	37	mead	mead	NOUN
fnp-3528	785	38	,	,	PUNCT
fnp-3528	785	39	s.	s.	PROPN
fnp-3528	785	40	;	;	PUNCT
fnp-3528	785	41	van	van	PROPN
fnp-3528	785	42	der	der	NOUN
fnp-3528	785	43	flier	flier	NOUN
fnp-3528	785	44	,	,	PUNCT
fnp-3528	785	45	w.	w.	PROPN
fnp-3528	785	46	m.	m.	NOUN
fnp-3528	785	47	;	;	PUNCT
fnp-3528	785	48	van	van	PROPN
fnp-3528	785	49	duijn	duijn	PROPN
fnp-3528	785	50	,	,	PUNCT
fnp-3528	785	51	c.	c.	PROPN
fnp-3528	785	52	m.	m.	NOUN
fnp-3528	785	53	;	;	PUNCT
fnp-3528	785	54	williams	williams	PROPN
fnp-3528	785	55	,	,	PUNCT
fnp-3528	785	56	j.	j.	PROPN
fnp-3528	785	57	;	;	PUNCT
fnp-3528	785	58	nicolas	nicolas	PROPN
fnp-3528	785	59	,	,	PUNCT
fnp-3528	785	60	g.	g.	PROPN
fnp-3528	785	61	;	;	PUNCT
fnp-3528	785	62	bellenguez	bellenguez	PROPN
fnp-3528	785	63	,	,	PUNCT
fnp-3528	785	64	c.	c.	PROPN
fnp-3528	785	65	;	;	PUNCT
fnp-3528	785	66	lambert	lambert	PROPN
fnp-3528	785	67	,	,	PUNCT
fnp-3528	785	68	j.-c	j.-c	PROPN
fnp-3528	785	69	.	.	PUNCT
fnp-3528	786	1	exome	exome	NOUN
fnp-3528	786	2	sequencing	sequence	VERB
fnp-3528	786	3	identifies	identify	VERB
fnp-3528	786	4	rare	rare	ADJ
fnp-3528	786	5	damaging	damaging	ADJ
fnp-3528	786	6	variants	variant	NOUN
fnp-3528	786	7	in	in	ADP
fnp-3528	786	8	the	the	DET
fnp-3528	786	9	atp8b4	atp8b4	ADJ
fnp-3528	786	10	and	and	CCONJ
fnp-3528	786	11	abca1	abca1	NOUN
fnp-3528	786	12	genes	gene	NOUN
fnp-3528	786	13	as	as	ADP
fnp-3528	786	14	novel	novel	ADJ
fnp-3528	786	15	risk	risk	NOUN
fnp-3528	786	16	factors	factor	NOUN
fnp-3528	786	17	for	for	ADP
fnp-3528	786	18	alzheimer	alzheimer	PROPN
fnp-3528	786	19	’s	’s	PART
fnp-3528	786	20	disease	disease	NOUN
fnp-3528	786	21	.	.	PUNCT
fnp-3528	787	1	medrxiv	medrxiv	PROPN
fnp-3528	787	2	2021	2021	NUM
fnp-3528	787	3	,	,	PUNCT
fnp-3528	787	4	2020.07.22.20159251	2020.07.22.20159251	PROPN
fnp-3528	787	5	.	.	PUNCT
fnp-3528	787	6	alrasadi	alrasadi	PROPN
fnp-3528	787	7	,	,	PUNCT
fnp-3528	787	8	k.	k.	PROPN
fnp-3528	787	9	;	;	PUNCT
fnp-3528	787	10	ruel	ruel	PROPN
fnp-3528	787	11	,	,	PUNCT
fnp-3528	787	12	i.	i.	PROPN
fnp-3528	787	13	l.	l.	PROPN
fnp-3528	787	14	;	;	PUNCT
fnp-3528	787	15	marcil	marcil	PROPN
fnp-3528	787	16	,	,	PUNCT
fnp-3528	787	17	m.	m.	NOUN
fnp-3528	787	18	;	;	PUNCT
fnp-3528	787	19	genest	genest	PROPN
fnp-3528	787	20	,	,	PUNCT
fnp-3528	787	21	j.	j.	PROPN
fnp-3528	787	22	functional	functional	ADJ
fnp-3528	787	23	mutations	mutation	NOUN
fnp-3528	787	24	of	of	ADP
fnp-3528	787	25	the	the	DET
fnp-3528	787	26	abca1	abca1	NOUN
fnp-3528	787	27	gene	gene	NOUN
fnp-3528	787	28	in	in	ADP
fnp-3528	787	29	subjects	subject	NOUN
fnp-3528	787	30	of	of	ADP
fnp-3528	787	31	french	french	ADJ
fnp-3528	787	32	-	-	PUNCT
fnp-3528	787	33	canadian	canadian	ADJ
fnp-3528	787	34	descent	descent	NOUN
fnp-3528	787	35	with	with	ADP
fnp-3528	787	36	hdl	hdl	NOUN
fnp-3528	787	37	deficiency	deficiency	NOUN
fnp-3528	787	38	.	.	PUNCT
fnp-3528	788	1	atheroscler	atheroscler	PROPN
fnp-3528	788	2	2006	2006	NUM
fnp-3528	788	3	,	,	PUNCT
fnp-3528	788	4	188	188	NUM
fnp-3528	788	5	,	,	PUNCT
fnp-3528	788	6	281	281	NUM
fnp-3528	788	7	-	-	SYM
fnp-3528	788	8	91	91	NUM
fnp-3528	788	9	.	.	PUNCT
fnp-3528	789	1	ma	ma	PROPN
fnp-3528	789	2	,	,	PUNCT
fnp-3528	789	3	x.	x.	PROPN
fnp-3528	789	4	;	;	PUNCT
fnp-3528	789	5	wang	wang	PROPN
fnp-3528	789	6	,	,	PUNCT
fnp-3528	789	7	t.	t.	PROPN
fnp-3528	789	8	;	;	PUNCT
fnp-3528	789	9	zhao	zhao	PROPN
fnp-3528	789	10	,	,	PUNCT
fnp-3528	789	11	z.	z.	PROPN
fnp-3528	789	12	l.	l.	PROPN
fnp-3528	789	13	;	;	PUNCT
fnp-3528	789	14	jiang	jiang	PROPN
fnp-3528	789	15	,	,	PUNCT
fnp-3528	789	16	y.	y.	PROPN
fnp-3528	789	17	;	;	PUNCT
fnp-3528	789	18	ye	ye	PROPN
fnp-3528	789	19	,	,	PUNCT
fnp-3528	789	20	s.	s.	PROPN
fnp-3528	789	21	propofol	propofol	NOUN
fnp-3528	789	22	suppresses	suppress	VERB
fnp-3528	789	23	proinflammatory	proinflammatory	ADJ
fnp-3528	789	24	cytokine	cytokine	NOUN
fnp-3528	789	25	production	production	NOUN
fnp-3528	789	26	by	by	ADP
fnp-3528	789	27	increasing	increase	VERB
fnp-3528	789	28	abca1	abca1	NOUN
fnp-3528	789	29	expression	expression	NOUN
fnp-3528	789	30	via	via	ADP
fnp-3528	789	31	mediation	mediation	NOUN
fnp-3528	789	32	by	by	ADP
fnp-3528	789	33	the	the	DET
fnp-3528	789	34	long	long	ADJ
fnp-3528	789	35	noncoding	noncoding	NOUN
fnp-3528	789	36	rna	rna	NOUN
fnp-3528	789	37	loc286367	loc286367	NOUN
fnp-3528	789	38	.	.	PUNCT
fnp-3528	790	1	mediators	mediator	NOUN
fnp-3528	790	2	inflamm	inflamm	PROPN
fnp-3528	790	3	2018	2018	NUM
fnp-3528	790	4	,	,	PUNCT
fnp-3528	790	5	2018	2018	NUM
fnp-3528	790	6	,	,	PUNCT
fnp-3528	790	7	8907143	8907143	NUM
fnp-3528	790	8	.	.	PUNCT
fnp-3528	791	1	koldamova	koldamova	PROPN
fnp-3528	791	2	,	,	PUNCT
fnp-3528	791	3	r.	r.	PROPN
fnp-3528	791	4	;	;	PUNCT
fnp-3528	791	5	staufenbiel	staufenbiel	PROPN
fnp-3528	791	6	,	,	PUNCT
fnp-3528	791	7	m.	m.	NOUN
fnp-3528	791	8	;	;	PUNCT
fnp-3528	791	9	lefterov	lefterov	X
fnp-3528	791	10	,	,	PUNCT
fnp-3528	791	11	i.	i.	NOUN
fnp-3528	791	12	lack	lack	NOUN
fnp-3528	791	13	of	of	ADP
fnp-3528	791	14	abca1	abca1	NOUN
fnp-3528	791	15	considerably	considerably	ADV
fnp-3528	791	16	decreases	decrease	VERB
fnp-3528	791	17	brain	brain	NOUN
fnp-3528	791	18	apoe	apoe	ADJ
fnp-3528	791	19	level	level	NOUN
fnp-3528	791	20	and	and	CCONJ
fnp-3528	791	21	increases	increase	VERB
fnp-3528	791	22	amyloid	amyloid	NOUN
fnp-3528	791	23	deposition	deposition	NOUN
fnp-3528	791	24	in	in	ADP
fnp-3528	791	25	app23	app23	PROPN
fnp-3528	791	26	mice	mouse	NOUN
fnp-3528	791	27	.	.	PUNCT
fnp-3528	792	1	j	j	PROPN
fnp-3528	792	2	biol	biol	PROPN
fnp-3528	792	3	chem	chem	NOUN
fnp-3528	792	4	2005	2005	NUM
fnp-3528	792	5	,	,	PUNCT
fnp-3528	792	6	280	280	NUM
fnp-3528	792	7	,	,	PUNCT
fnp-3528	792	8	43224	43224	NUM
fnp-3528	792	9	-	-	SYM
fnp-3528	792	10	35	35	NUM
fnp-3528	792	11	.	.	PUNCT
fnp-3528	793	1	wahrle	wahrle	NOUN
fnp-3528	793	2	,	,	PUNCT
fnp-3528	793	3	s.	s.	PROPN
fnp-3528	793	4	e.	e.	PROPN
fnp-3528	793	5	;	;	PUNCT
fnp-3528	793	6	jiang	jiang	PROPN
fnp-3528	793	7	,	,	PUNCT
fnp-3528	793	8	h.	h.	PROPN
fnp-3528	793	9	;	;	PUNCT
fnp-3528	793	10	parsadanian	parsadanian	ADJ
fnp-3528	793	11	,	,	PUNCT
fnp-3528	793	12	m.	m.	NOUN
fnp-3528	793	13	;	;	PUNCT
fnp-3528	793	14	hartman	hartman	PROPN
fnp-3528	793	15	,	,	PUNCT
fnp-3528	793	16	r.	r.	PROPN
fnp-3528	793	17	e.	e.	PROPN
fnp-3528	793	18	;	;	PUNCT
fnp-3528	793	19	bales	bale	NOUN
fnp-3528	793	20	,	,	PUNCT
fnp-3528	793	21	k.	k.	PROPN
fnp-3528	793	22	r.	r.	PROPN
fnp-3528	793	23	;	;	PUNCT
fnp-3528	793	24	paul	paul	PROPN
fnp-3528	793	25	,	,	PUNCT
fnp-3528	793	26	s.	s.	PROPN
fnp-3528	793	27	m.	m.	PROPN
fnp-3528	793	28	;	;	PUNCT
fnp-3528	793	29	holtzman	holtzman	NOUN
fnp-3528	793	30	,	,	PUNCT
fnp-3528	793	31	d.	d.	PROPN
fnp-3528	793	32	m.	m.	NOUN
fnp-3528	793	33	deletion	deletion	NOUN
fnp-3528	793	34	of	of	ADP
fnp-3528	793	35	abca1	abca1	NOUN
fnp-3528	793	36	increases	increase	VERB
fnp-3528	793	37	abeta	abeta	ADJ
fnp-3528	793	38	deposition	deposition	NOUN
fnp-3528	793	39	in	in	ADP
fnp-3528	793	40	the	the	DET
fnp-3528	793	41	pdapp	pdapp	ADJ
fnp-3528	793	42	transgenic	transgenic	NOUN
fnp-3528	793	43	mouse	mouse	NOUN
fnp-3528	793	44	model	model	NOUN
fnp-3528	793	45	of	of	ADP
fnp-3528	793	46	alzheimer	alzheimer	PROPN
fnp-3528	793	47	disease	disease	PROPN
fnp-3528	793	48	.	.	PUNCT
fnp-3528	794	1	j	j	PROPN
fnp-3528	794	2	biol	biol	PROPN
fnp-3528	794	3	chem	chem	NOUN
fnp-3528	794	4	2005	2005	NUM
fnp-3528	794	5	,	,	PUNCT
fnp-3528	794	6	280	280	NUM
fnp-3528	794	7	,	,	PUNCT
fnp-3528	794	8	43236	43236	NUM
fnp-3528	794	9	-	-	SYM
fnp-3528	794	10	42	42	NUM
fnp-3528	794	11	.	.	PUNCT
fnp-3528	795	1	hirsch	hirsch	PROPN
fnp-3528	795	2	-	-	PUNCT
fnp-3528	795	3	reinshagen	reinshagen	PROPN
fnp-3528	795	4	,	,	PUNCT
fnp-3528	795	5	v.	v.	ADV
fnp-3528	795	6	;	;	PUNCT
fnp-3528	795	7	maia	maia	PROPN
fnp-3528	795	8	,	,	PUNCT
fnp-3528	795	9	l.	l.	PROPN
fnp-3528	795	10	f.	f.	PROPN
fnp-3528	795	11	;	;	PUNCT
fnp-3528	795	12	burgess	burgess	PROPN
fnp-3528	795	13	,	,	PUNCT
fnp-3528	795	14	b.	b.	PROPN
fnp-3528	795	15	l.	l.	PROPN
fnp-3528	795	16	;	;	PUNCT
fnp-3528	795	17	blain	blain	PROPN
fnp-3528	795	18	,	,	PUNCT
fnp-3528	795	19	j.	j.	PROPN
fnp-3528	795	20	f.	f.	PROPN
fnp-3528	795	21	;	;	PUNCT
fnp-3528	795	22	naus	naus	PROPN
fnp-3528	795	23	,	,	PUNCT
fnp-3528	795	24	k.	k.	PROPN
fnp-3528	795	25	e.	e.	PROPN
fnp-3528	795	26	;	;	PUNCT
fnp-3528	795	27	mcisaac	mcisaac	PROPN
fnp-3528	795	28	,	,	PUNCT
fnp-3528	795	29	s.	s.	PROPN
fnp-3528	795	30	a.	a.	PROPN
fnp-3528	795	31	;	;	PUNCT
fnp-3528	795	32	parkinson	parkinson	NOUN
fnp-3528	795	33	,	,	PUNCT
fnp-3528	795	34	p.	p.	PROPN
fnp-3528	795	35	f.	f.	PROPN
fnp-3528	795	36	;	;	PUNCT
fnp-3528	795	37	chan	chan	PROPN
fnp-3528	795	38	,	,	PUNCT
fnp-3528	795	39	j.	j.	PROPN
fnp-3528	795	40	y.	y.	PROPN
fnp-3528	795	41	;	;	PUNCT
fnp-3528	795	42	tansley	tansley	NOUN
fnp-3528	795	43	,	,	PUNCT
fnp-3528	795	44	g.	g.	PROPN
fnp-3528	795	45	h.	h.	PROPN
fnp-3528	795	46	;	;	PUNCT
fnp-3528	795	47	hayden	hayden	PROPN
fnp-3528	795	48	,	,	PUNCT
fnp-3528	795	49	m.	m.	PROPN
fnp-3528	795	50	r.	r.	PROPN
fnp-3528	795	51	;	;	PUNCT
fnp-3528	795	52	poirier	poirier	PROPN
fnp-3528	795	53	,	,	PUNCT
fnp-3528	795	54	j.	j.	PROPN
fnp-3528	795	55	;	;	PUNCT
fnp-3528	795	56	van	van	PROPN
fnp-3528	795	57	nostrand	nostrand	PROPN
fnp-3528	795	58	,	,	PUNCT
fnp-3528	795	59	w.	w.	PROPN
fnp-3528	795	60	;	;	PUNCT
fnp-3528	795	61	wellington	wellington	PROPN
fnp-3528	795	62	,	,	PUNCT
fnp-3528	795	63	c.	c.	PROPN
fnp-3528	795	64	l.	l.	PROPN
fnp-3528	795	65	the	the	DET
fnp-3528	795	66	absence	absence	NOUN
fnp-3528	795	67	of	of	ADP
fnp-3528	795	68	abca1	abca1	NOUN
fnp-3528	795	69	decreases	decrease	VERB
fnp-3528	795	70	soluble	soluble	ADJ
fnp-3528	795	71	apoe	apoe	ADJ
fnp-3528	795	72	levels	level	NOUN
fnp-3528	795	73	but	but	CCONJ
fnp-3528	795	74	does	do	AUX
fnp-3528	795	75	not	not	PART
fnp-3528	795	76	diminish	diminish	VERB
fnp-3528	795	77	amyloid	amyloid	NOUN
fnp-3528	795	78	deposition	deposition	NOUN
fnp-3528	795	79	in	in	ADP
fnp-3528	795	80	two	two	NUM
fnp-3528	795	81	murine	murine	ADJ
fnp-3528	795	82	models	model	NOUN
fnp-3528	795	83	of	of	ADP
fnp-3528	795	84	alzheimer	alzheimer	PROPN
fnp-3528	795	85	disease	disease	PROPN
fnp-3528	795	86	.	.	PUNCT
fnp-3528	796	1	j	j	PROPN
fnp-3528	796	2	biol	biol	PROPN
fnp-3528	796	3	chem	chem	NOUN
fnp-3528	796	4	2005	2005	NUM
fnp-3528	796	5	,	,	PUNCT
fnp-3528	796	6	280	280	NUM
fnp-3528	796	7	,	,	PUNCT
fnp-3528	796	8	43243	43243	NUM
fnp-3528	796	9	-	-	SYM
fnp-3528	796	10	56	56	NUM
fnp-3528	796	11	.	.	PUNCT
fnp-3528	797	1	fitz	fitz	PROPN
fnp-3528	797	2	,	,	PUNCT
fnp-3528	797	3	n.	n.	PROPN
fnp-3528	797	4	f.	f.	PROPN
fnp-3528	797	5	;	;	PUNCT
fnp-3528	797	6	nam	nam	PROPN
fnp-3528	797	7	,	,	PUNCT
fnp-3528	797	8	k.	k.	PROPN
fnp-3528	797	9	n.	n.	PROPN
fnp-3528	797	10	;	;	PUNCT
fnp-3528	797	11	wolfe	wolfe	PROPN
fnp-3528	797	12	,	,	PUNCT
fnp-3528	797	13	c.	c.	PROPN
fnp-3528	797	14	m.	m.	NOUN
fnp-3528	797	15	;	;	PUNCT
fnp-3528	797	16	letronne	letronne	PROPN
fnp-3528	797	17	,	,	PUNCT
fnp-3528	797	18	f.	f.	PROPN
fnp-3528	797	19	;	;	PUNCT
fnp-3528	797	20	playso	playso	PROPN
fnp-3528	797	21	,	,	PUNCT
fnp-3528	797	22	b.	b.	PROPN
fnp-3528	797	23	e.	e.	PROPN
fnp-3528	797	24	;	;	PUNCT
fnp-3528	797	25	iordanova	iordanova	PROPN
fnp-3528	797	26	,	,	PUNCT
fnp-3528	797	27	b.	b.	PROPN
fnp-3528	797	28	e.	e.	PROPN
fnp-3528	797	29	;	;	PUNCT
fnp-3528	797	30	kozai	kozai	PROPN
fnp-3528	797	31	,	,	PUNCT
fnp-3528	797	32	t.	t.	PROPN
fnp-3528	797	33	d.	d.	PROPN
fnp-3528	797	34	y.	y.	PROPN
fnp-3528	797	35	;	;	PUNCT
fnp-3528	797	36	biedrzycki	biedrzycki	PROPN
fnp-3528	797	37	,	,	PUNCT
fnp-3528	797	38	r.	r.	PROPN
fnp-3528	797	39	j.	j.	PROPN
fnp-3528	797	40	;	;	PUNCT
fnp-3528	797	41	kagan	kagan	PROPN
fnp-3528	797	42	,	,	PUNCT
fnp-3528	797	43	v.	v.	PROPN
fnp-3528	797	44	e.	e.	PROPN
fnp-3528	797	45	;	;	PUNCT
fnp-3528	797	46	tyurina	tyurina	PROPN
fnp-3528	797	47	,	,	PUNCT
fnp-3528	797	48	y.	y.	PROPN
fnp-3528	797	49	y.	y.	PROPN
fnp-3528	797	50	;	;	PUNCT
fnp-3528	797	51	han	han	PROPN
fnp-3528	797	52	,	,	PUNCT
fnp-3528	797	53	x.	x.	NOUN
fnp-3528	797	54	;	;	PUNCT
fnp-3528	797	55	lefterov	lefterov	PROPN
fnp-3528	797	56	,	,	PUNCT
fnp-3528	797	57	i.	i.	NOUN
fnp-3528	797	58	;	;	PUNCT
fnp-3528	797	59	koldamova	koldamova	PROPN
fnp-3528	797	60	,	,	PUNCT
fnp-3528	797	61	r.	r.	PROPN
fnp-3528	797	62	phospholipids	phospholipid	NOUN
fnp-3528	797	63	of	of	ADP
fnp-3528	797	64	apoe	apoe	ADJ
fnp-3528	797	65	lipoproteins	lipoprotein	NOUN
fnp-3528	797	66	activate	activate	VERB
fnp-3528	797	67	microglia	microglia	NOUN
fnp-3528	797	68	in	in	ADP
fnp-3528	797	69	an	an	DET
fnp-3528	797	70	isoform	isoform	NOUN
fnp-3528	797	71	-	-	PUNCT
fnp-3528	797	72	specific	specific	ADJ
fnp-3528	797	73	manner	manner	NOUN
fnp-3528	797	74	in	in	ADP
fnp-3528	797	75	preclinical	preclinical	ADJ
fnp-3528	797	76	models	model	NOUN
fnp-3528	797	77	of	of	ADP
fnp-3528	797	78	alzheimer	alzheimer	PROPN
fnp-3528	797	79	's	's	PART
fnp-3528	797	80	disease	disease	NOUN
fnp-3528	797	81	.	.	PUNCT
fnp-3528	798	1	nat	nat	PROPN
fnp-3528	798	2	commun	commun	PROPN
fnp-3528	798	3	2021	2021	NUM
fnp-3528	798	4	,	,	PUNCT
fnp-3528	798	5	12	12	NUM
fnp-3528	798	6	,	,	PUNCT
fnp-3528	798	7	3416	3416	NUM
fnp-3528	798	8	.	.	PUNCT
fnp-3528	799	1	deane	deane	PROPN
fnp-3528	799	2	,	,	PUNCT
fnp-3528	799	3	r.	r.	PROPN
fnp-3528	799	4	;	;	PUNCT
fnp-3528	799	5	sagare	sagare	PROPN
fnp-3528	799	6	,	,	PUNCT
fnp-3528	799	7	a.	a.	NOUN
fnp-3528	799	8	;	;	PUNCT
fnp-3528	799	9	hamm	hamm	PROPN
fnp-3528	799	10	,	,	PUNCT
fnp-3528	799	11	k.	k.	PROPN
fnp-3528	799	12	;	;	PUNCT
fnp-3528	799	13	parisi	parisi	PROPN
fnp-3528	799	14	,	,	PUNCT
fnp-3528	799	15	m.	m.	NOUN
fnp-3528	799	16	;	;	PUNCT
fnp-3528	799	17	lane	lane	PROPN
fnp-3528	799	18	,	,	PUNCT
fnp-3528	799	19	s.	s.	PROPN
fnp-3528	799	20	;	;	PUNCT
fnp-3528	799	21	finn	finn	PROPN
fnp-3528	799	22	,	,	PUNCT
fnp-3528	799	23	m.	m.	PROPN
fnp-3528	799	24	b.	b.	PROPN
fnp-3528	799	25	;	;	PUNCT
fnp-3528	799	26	holtzman	holtzman	PROPN
fnp-3528	799	27	,	,	PUNCT
fnp-3528	799	28	d.	d.	PROPN
fnp-3528	799	29	m.	m.	PROPN
fnp-3528	799	30	;	;	PUNCT
fnp-3528	799	31	zlokovic	zlokovic	VERB
fnp-3528	799	32	,	,	PUNCT
fnp-3528	799	33	b.	b.	PROPN
fnp-3528	800	1	v.	v.	CCONJ
fnp-3528	800	2	apoe	apoe	ADJ
fnp-3528	800	3	isoform	isoform	NOUN
fnp-3528	800	4	-	-	PUNCT
fnp-3528	800	5	specific	specific	ADJ
fnp-3528	800	6	disruption	disruption	NOUN
fnp-3528	800	7	of	of	ADP
fnp-3528	800	8	amyloid	amyloid	NOUN
fnp-3528	800	9	beta	beta	NOUN
fnp-3528	800	10	peptide	peptide	NOUN
fnp-3528	800	11	clearance	clearance	NOUN
fnp-3528	800	12	from	from	ADP
fnp-3528	800	13	mouse	mouse	NOUN
fnp-3528	800	14	brain	brain	NOUN
fnp-3528	800	15	.	.	PUNCT
fnp-3528	801	1	j	j	PROPN
fnp-3528	801	2	clin	clin	PROPN
fnp-3528	801	3	invest	invest	VERB
fnp-3528	801	4	2008	2008	NUM
fnp-3528	801	5	,	,	PUNCT
fnp-3528	801	6	118	118	NUM
fnp-3528	801	7	,	,	PUNCT
fnp-3528	801	8	4002	4002	NUM
fnp-3528	801	9	-	-	SYM
fnp-3528	801	10	13	13	NUM
fnp-3528	801	11	.	.	PUNCT
fnp-3528	802	1	basak	basak	PROPN
fnp-3528	802	2	,	,	PUNCT
fnp-3528	802	3	j.	j.	PROPN
fnp-3528	802	4	m.	m.	PROPN
fnp-3528	802	5	;	;	PUNCT
fnp-3528	802	6	kim	kim	PROPN
fnp-3528	802	7	,	,	PUNCT
fnp-3528	802	8	j.	j.	PROPN
fnp-3528	802	9	;	;	PUNCT
fnp-3528	802	10	pyatkivskyy	pyatkivskyy	NOUN
fnp-3528	802	11	,	,	PUNCT
fnp-3528	802	12	y.	y.	PROPN
fnp-3528	802	13	;	;	PUNCT
fnp-3528	802	14	wildsmith	wildsmith	PROPN
fnp-3528	802	15	,	,	PUNCT
fnp-3528	802	16	k.	k.	PROPN
fnp-3528	802	17	r.	r.	PROPN
fnp-3528	802	18	;	;	PUNCT
fnp-3528	802	19	jiang	jiang	PROPN
fnp-3528	802	20	,	,	PUNCT
fnp-3528	802	21	h.	h.	PROPN
fnp-3528	802	22	;	;	PUNCT
fnp-3528	802	23	parsadanian	parsadanian	ADJ
fnp-3528	802	24	,	,	PUNCT
fnp-3528	802	25	m.	m.	NOUN
fnp-3528	802	26	;	;	PUNCT
fnp-3528	802	27	patterson	patterson	PROPN
fnp-3528	802	28	,	,	PUNCT
fnp-3528	802	29	b.	b.	PROPN
fnp-3528	802	30	w.	w.	PROPN
fnp-3528	802	31	;	;	PUNCT
fnp-3528	802	32	bateman	bateman	PROPN
fnp-3528	802	33	,	,	PUNCT
fnp-3528	802	34	r.	r.	PROPN
fnp-3528	802	35	j.	j.	PROPN
fnp-3528	802	36	;	;	PUNCT
fnp-3528	802	37	holtzman	holtzman	PROPN
fnp-3528	802	38	,	,	PUNCT
fnp-3528	802	39	d.	d.	PROPN
fnp-3528	802	40	m.	m.	PROPN
fnp-3528	802	41	measurement	measurement	NOUN
fnp-3528	802	42	of	of	ADP
fnp-3528	802	43	apolipoprotein	apolipoprotein	ADJ
fnp-3528	802	44	e	e	PROPN
fnp-3528	802	45	and	and	CCONJ
fnp-3528	802	46	amyloid	amyloid	VERB
fnp-3528	802	47	beta	beta	ADJ
fnp-3528	802	48	clearance	clearance	NOUN
fnp-3528	802	49	rates	rate	NOUN
fnp-3528	802	50	in	in	ADP
fnp-3528	802	51	the	the	DET
fnp-3528	802	52	mouse	mouse	NOUN
fnp-3528	802	53	brain	brain	NOUN
fnp-3528	802	54	using	use	VERB
fnp-3528	802	55	bolus	bolus	ADJ
fnp-3528	802	56	stable	stable	ADJ
fnp-3528	802	57	isotope	isotope	NOUN
fnp-3528	802	58	labeling	labeling	NOUN
fnp-3528	802	59	.	.	PUNCT
fnp-3528	803	1	mol	mol	ADP
fnp-3528	803	2	neurodegener	neurodegener	NOUN
fnp-3528	803	3	2012	2012	NUM
fnp-3528	803	4	,	,	PUNCT
fnp-3528	803	5	7	7	NUM
fnp-3528	803	6	,	,	PUNCT
fnp-3528	803	7	14	14	NUM
fnp-3528	803	8	.	.	PUNCT
fnp-3528	804	1	fitz	fitz	PROPN
fnp-3528	804	2	,	,	PUNCT
fnp-3528	804	3	n.	n.	PROPN
fnp-3528	804	4	f.	f.	PROPN
fnp-3528	804	5	;	;	PUNCT
fnp-3528	804	6	tapias	tapia	NOUN
fnp-3528	804	7	,	,	PUNCT
fnp-3528	804	8	v.	v.	ADV
fnp-3528	804	9	;	;	PUNCT
fnp-3528	804	10	cronican	cronican	PROPN
fnp-3528	804	11	,	,	PUNCT
fnp-3528	804	12	a.	a.	NOUN
fnp-3528	804	13	a.	a.	NOUN
fnp-3528	804	14	;	;	PUNCT
fnp-3528	804	15	castranio	castranio	PROPN
fnp-3528	804	16	,	,	PUNCT
fnp-3528	804	17	e.	e.	PROPN
fnp-3528	804	18	l.	l.	PROPN
fnp-3528	804	19	;	;	PUNCT
fnp-3528	804	20	saleem	saleem	PROPN
fnp-3528	804	21	,	,	PUNCT
fnp-3528	804	22	m.	m.	NOUN
fnp-3528	804	23	;	;	PUNCT
fnp-3528	804	24	carter	carter	PROPN
fnp-3528	804	25	,	,	PUNCT
fnp-3528	804	26	a.	a.	PROPN
fnp-3528	804	27	y.	y.	PROPN
fnp-3528	804	28	;	;	PUNCT
fnp-3528	804	29	lefterova	lefterova	PROPN
fnp-3528	804	30	,	,	PUNCT
fnp-3528	804	31	m.	m.	NOUN
fnp-3528	804	32	;	;	PUNCT
fnp-3528	804	33	lefterov	lefterov	PROPN
fnp-3528	804	34	,	,	PUNCT
fnp-3528	804	35	i.	i.	NOUN
fnp-3528	804	36	;	;	PUNCT
fnp-3528	804	37	koldamova	koldamova	PROPN
fnp-3528	804	38	,	,	PUNCT
fnp-3528	804	39	r.	r.	PROPN
fnp-3528	804	40	opposing	opposing	ADJ
fnp-3528	804	41	effects	effect	NOUN
fnp-3528	804	42	of	of	ADP
fnp-3528	804	43	apoe	apoe	NOUN
fnp-3528	804	44	/	/	SYM
fnp-3528	804	45	apoa1	apoa1	X
fnp-3528	804	46	double	double	ADJ
fnp-3528	804	47	deletion	deletion	NOUN
fnp-3528	804	48	on	on	ADP
fnp-3528	804	49	amyloid	amyloid	NOUN
fnp-3528	804	50	-	-	PUNCT
fnp-3528	804	51	beta	beta	NOUN
fnp-3528	804	52	pathology	pathology	NOUN
fnp-3528	804	53	and	and	CCONJ
fnp-3528	804	54	cognitive	cognitive	ADJ
fnp-3528	804	55	performance	performance	NOUN
fnp-3528	804	56	in	in	ADP
fnp-3528	804	57	app	app	NOUN
fnp-3528	804	58	mice	mouse	NOUN
fnp-3528	804	59	.	.	PUNCT
fnp-3528	805	1	brain	brain	NOUN
fnp-3528	805	2	2015	2015	NUM
fnp-3528	805	3	,	,	PUNCT
fnp-3528	805	4	138	138	NUM
fnp-3528	805	5	,	,	PUNCT
fnp-3528	805	6	3699	3699	NUM
fnp-3528	805	7	-	-	SYM
fnp-3528	805	8	715	715	NUM
fnp-3528	805	9	.	.	PUNCT
fnp-3528	806	1	lefterov	lefterov	PROPN
fnp-3528	806	2	,	,	PUNCT
fnp-3528	806	3	i.	i.	NOUN
fnp-3528	806	4	;	;	PUNCT
fnp-3528	806	5	fitz	fitz	PROPN
fnp-3528	806	6	,	,	PUNCT
fnp-3528	806	7	n.	n.	PROPN
fnp-3528	806	8	f.	f.	PROPN
fnp-3528	806	9	;	;	PUNCT
fnp-3528	806	10	cronican	cronican	PROPN
fnp-3528	806	11	,	,	PUNCT
fnp-3528	806	12	a.	a.	NOUN
fnp-3528	806	13	;	;	PUNCT
fnp-3528	806	14	lefterov	lefterov	ADJ
fnp-3528	806	15	,	,	PUNCT
fnp-3528	806	16	p.	p.	NOUN
fnp-3528	806	17	;	;	PUNCT
fnp-3528	806	18	staufenbiel	staufenbiel	PROPN
fnp-3528	806	19	,	,	PUNCT
fnp-3528	806	20	m.	m.	NOUN
fnp-3528	806	21	;	;	PUNCT
fnp-3528	806	22	koldamova	koldamova	PROPN
fnp-3528	806	23	,	,	PUNCT
fnp-3528	806	24	r.	r.	PROPN
fnp-3528	806	25	memory	memory	NOUN
fnp-3528	806	26	deficits	deficit	NOUN
fnp-3528	806	27	in	in	ADP
fnp-3528	806	28	app23	app23	PROPN
fnp-3528	806	29	/	/	SYM
fnp-3528	806	30	abca1+/mice	abca1+/mice	PROPN
fnp-3528	806	31	correlate	correlate	ADJ
fnp-3528	806	32	with	with	ADP
fnp-3528	806	33	the	the	DET
fnp-3528	806	34	level	level	NOUN
fnp-3528	806	35	of	of	ADP
fnp-3528	806	36	abeta	abeta	NOUN
fnp-3528	806	37	oligomers	oligomer	NOUN
fnp-3528	806	38	.	.	PUNCT
fnp-3528	807	1	asn	asn	PROPN
fnp-3528	807	2	neuro	neuro	PROPN
fnp-3528	807	3	2009	2009	NUM
fnp-3528	807	4	,	,	PUNCT
fnp-3528	807	5	1	1	NUM
fnp-3528	807	6	,	,	PUNCT
fnp-3528	807	7	e00006	e00006	NOUN
fnp-3528	807	8	.	.	PUNCT
fnp-3528	807	9	fitz	fitz	PROPN
fnp-3528	807	10	,	,	PUNCT
fnp-3528	807	11	n.	n.	PROPN
fnp-3528	807	12	f.	f.	PROPN
fnp-3528	807	13	;	;	PUNCT
fnp-3528	807	14	cronican	cronican	PROPN
fnp-3528	807	15	,	,	PUNCT
fnp-3528	807	16	a.	a.	NOUN
fnp-3528	807	17	a.	a.	NOUN
fnp-3528	807	18	;	;	PUNCT
fnp-3528	808	1	saleem	saleem	PROPN
fnp-3528	808	2	,	,	PUNCT
fnp-3528	808	3	m.	m.	NOUN
fnp-3528	808	4	;	;	PUNCT
fnp-3528	808	5	fauq	fauq	NOUN
fnp-3528	808	6	,	,	PUNCT
fnp-3528	808	7	a.	a.	PROPN
fnp-3528	808	8	h.	h.	PROPN
fnp-3528	808	9	;	;	PUNCT
fnp-3528	808	10	chapman	chapman	PROPN
fnp-3528	808	11	,	,	PUNCT
fnp-3528	808	12	r.	r.	PROPN
fnp-3528	808	13	;	;	PUNCT
fnp-3528	808	14	lefterov	lefterov	PROPN
fnp-3528	808	15	,	,	PUNCT
fnp-3528	808	16	i.	i.	NOUN
fnp-3528	808	17	;	;	PUNCT
fnp-3528	808	18	koldamova	koldamova	PROPN
fnp-3528	808	19	,	,	PUNCT
fnp-3528	808	20	r.	r.	PROPN
fnp-3528	808	21	abca1	abca1	PROPN
fnp-3528	808	22	deficiency	deficiency	NOUN
fnp-3528	808	23	affects	affect	VERB
fnp-3528	808	24	alzheimer	alzheimer	PROPN
fnp-3528	808	25	's	's	PART
fnp-3528	808	26	disease	disease	NOUN
fnp-3528	808	27	-	-	PUNCT
fnp-3528	808	28	like	like	ADJ
fnp-3528	808	29	phenotype	phenotype	NOUN
fnp-3528	808	30	in	in	ADP
fnp-3528	808	31	human	human	ADJ
fnp-3528	808	32	apoe4	apoe4	PROPN
fnp-3528	808	33	but	but	CCONJ
fnp-3528	808	34	not	not	PART
fnp-3528	808	35	in	in	ADP
fnp-3528	808	36	apoe3	apoe3	ADV
fnp-3528	808	37	-	-	PUNCT
fnp-3528	808	38	targeted	target	VERB
fnp-3528	808	39	replacement	replacement	NOUN
fnp-3528	808	40	mice	mouse	NOUN
fnp-3528	808	41	.	.	PUNCT
fnp-3528	809	1	j	j	PROPN
fnp-3528	809	2	neurosci	neurosci	PROPN
fnp-3528	809	3	2012	2012	NUM
fnp-3528	809	4	,	,	PUNCT
fnp-3528	809	5	32	32	NUM
fnp-3528	809	6	,	,	PUNCT
fnp-3528	809	7	13125	13125	NUM
fnp-3528	809	8	-	-	SYM
fnp-3528	809	9	36	36	NUM
fnp-3528	809	10	.	.	PUNCT
fnp-3528	810	1	broccardo	broccardo	PROPN
fnp-3528	810	2	,	,	PUNCT
fnp-3528	810	3	c.	c.	NOUN
fnp-3528	810	4	;	;	PUNCT
fnp-3528	810	5	nieoullon	nieoullon	NOUN
fnp-3528	810	6	,	,	PUNCT
fnp-3528	810	7	v.	v.	PROPN
fnp-3528	810	8	;	;	PUNCT
fnp-3528	810	9	amin	amin	PROPN
fnp-3528	810	10	,	,	PUNCT
fnp-3528	810	11	r.	r.	PROPN
fnp-3528	810	12	;	;	PUNCT
fnp-3528	810	13	masmejean	masmejean	PROPN
fnp-3528	810	14	,	,	PUNCT
fnp-3528	810	15	f.	f.	PROPN
fnp-3528	810	16	;	;	PUNCT
fnp-3528	810	17	carta	carta	PROPN
fnp-3528	810	18	,	,	PUNCT
fnp-3528	810	19	s.	s.	PROPN
fnp-3528	810	20	;	;	PUNCT
fnp-3528	810	21	tassi	tassi	NOUN
fnp-3528	810	22	,	,	PUNCT
fnp-3528	810	23	s.	s.	PROPN
fnp-3528	810	24	;	;	PUNCT
fnp-3528	810	25	pophillat	pophillat	ADJ
fnp-3528	810	26	,	,	PUNCT
fnp-3528	810	27	m.	m.	NOUN
fnp-3528	810	28	;	;	PUNCT
fnp-3528	810	29	rubartelli	rubartelli	PROPN
fnp-3528	810	30	,	,	PUNCT
fnp-3528	810	31	a.	a.	NOUN
fnp-3528	810	32	;	;	PUNCT
fnp-3528	810	33	pierres	pierre	NOUN
fnp-3528	810	34	,	,	PUNCT
fnp-3528	810	35	m.	m.	NOUN
fnp-3528	810	36	;	;	PUNCT
fnp-3528	810	37	rougon	rougon	PROPN
fnp-3528	810	38	,	,	PUNCT
fnp-3528	810	39	g.	g.	PROPN
fnp-3528	810	40	;	;	PUNCT
fnp-3528	810	41	nieoullon	nieoullon	PROPN
fnp-3528	810	42	,	,	PUNCT
fnp-3528	810	43	a.	a.	NOUN
fnp-3528	810	44	;	;	PUNCT
fnp-3528	810	45	chazal	chazal	PROPN
fnp-3528	810	46	,	,	PUNCT
fnp-3528	810	47	g.	g.	PROPN
fnp-3528	810	48	;	;	PUNCT
fnp-3528	810	49	chimini	chimini	PROPN
fnp-3528	810	50	,	,	PUNCT
fnp-3528	810	51	g.	g.	PROPN
fnp-3528	810	52	abca2	abca2	PROPN
fnp-3528	810	53	is	be	AUX
fnp-3528	810	54	a	a	DET
fnp-3528	810	55	marker	marker	NOUN
fnp-3528	810	56	of	of	ADP
fnp-3528	810	57	neural	neural	ADJ
fnp-3528	810	58	progenitors	progenitor	NOUN
fnp-3528	810	59	and	and	CCONJ
fnp-3528	810	60	neuronal	neuronal	ADJ
fnp-3528	810	61	subsets	subset	NOUN
fnp-3528	810	62	in	in	ADP
fnp-3528	810	63	the	the	DET
fnp-3528	810	64	adult	adult	NOUN
fnp-3528	810	65	rodent	rodent	NOUN
fnp-3528	810	66	brain	brain	NOUN
fnp-3528	810	67	.	.	PUNCT
fnp-3528	811	1	j	j	PROPN
fnp-3528	811	2	neurochem	neurochem	PROPN
fnp-3528	811	3	2006	2006	NUM
fnp-3528	811	4	,	,	PUNCT
fnp-3528	811	5	97	97	NUM
fnp-3528	811	6	,	,	PUNCT
fnp-3528	811	7	345	345	NUM
fnp-3528	811	8	-	-	SYM
fnp-3528	811	9	55	55	NUM
fnp-3528	811	10	.	.	PUNCT
fnp-3528	812	1	vulevic	vulevic	PROPN
fnp-3528	812	2	,	,	PUNCT
fnp-3528	812	3	b.	b.	PROPN
fnp-3528	812	4	;	;	PUNCT
fnp-3528	812	5	chen	chen	PROPN
fnp-3528	812	6	,	,	PUNCT
fnp-3528	812	7	z.	z.	PROPN
fnp-3528	812	8	;	;	PUNCT
fnp-3528	812	9	boyd	boyd	PROPN
fnp-3528	812	10	,	,	PUNCT
fnp-3528	812	11	j.	j.	PROPN
fnp-3528	812	12	t.	t.	PROPN
fnp-3528	812	13	;	;	PUNCT
fnp-3528	812	14	davis	davis	PROPN
fnp-3528	812	15	,	,	PUNCT
fnp-3528	812	16	w.	w.	PROPN
fnp-3528	812	17	,	,	PUNCT
fnp-3528	812	18	jr	jr	PROPN
fnp-3528	812	19	.	.	PROPN
fnp-3528	812	20	;	;	PUNCT
fnp-3528	812	21	walsh	walsh	PROPN
fnp-3528	812	22	,	,	PUNCT
fnp-3528	812	23	e.	e.	PROPN
fnp-3528	812	24	s.	s.	PROPN
fnp-3528	812	25	;	;	PUNCT
fnp-3528	812	26	belinsky	belinsky	NOUN
fnp-3528	812	27	,	,	PUNCT
fnp-3528	812	28	m.	m.	NOUN
fnp-3528	812	29	g.	g.	PROPN
fnp-3528	812	30	;	;	PUNCT
fnp-3528	812	31	tew	tew	PROPN
fnp-3528	812	32	,	,	PUNCT
fnp-3528	812	33	k.	k.	PROPN
fnp-3528	812	34	d.	d.	PROPN
fnp-3528	812	35	cloning	cloning	NOUN
fnp-3528	812	36	and	and	CCONJ
fnp-3528	812	37	characterization	characterization	NOUN
fnp-3528	812	38	of	of	ADP
fnp-3528	812	39	human	human	ADJ
fnp-3528	812	40	adenosine	adenosine	ADJ
fnp-3528	812	41	5'-triphosphate	5'-triphosphate	NOUN
fnp-3528	812	42	-	-	PUNCT
fnp-3528	812	43	binding	bind	VERB
fnp-3528	812	44	cassette	cassette	NOUN
fnp-3528	812	45	,	,	PUNCT
fnp-3528	812	46	sub	sub	NOUN
fnp-3528	812	47	-	-	NOUN
fnp-3528	812	48	family	family	NOUN
fnp-3528	812	49	a	a	PRON
fnp-3528	812	50	,	,	PUNCT
fnp-3528	812	51	transporter	transporter	NOUN
fnp-3528	812	52	2	2	NUM
fnp-3528	812	53	(	(	PUNCT
fnp-3528	812	54	abca2	abca2	NOUN
fnp-3528	812	55	)	)	PUNCT
fnp-3528	812	56	.	.	PUNCT
fnp-3528	813	1	cancer	cancer	NOUN
fnp-3528	813	2	res	re	NOUN
fnp-3528	813	3	2001	2001	NUM
fnp-3528	813	4	,	,	PUNCT
fnp-3528	813	5	61	61	NUM
fnp-3528	813	6	,	,	PUNCT
fnp-3528	813	7	3339	3339	NUM
fnp-3528	813	8	-	-	SYM
fnp-3528	813	9	47	47	NUM
fnp-3528	813	10	.	.	PUNCT
fnp-3528	814	1	zhou	zhou	PROPN
fnp-3528	814	2	,	,	PUNCT
fnp-3528	814	3	c.	c.	PROPN
fnp-3528	814	4	;	;	PUNCT
fnp-3528	814	5	zhao	zhao	PROPN
fnp-3528	814	6	,	,	PUNCT
fnp-3528	814	7	l.	l.	PROPN
fnp-3528	814	8	;	;	PUNCT
fnp-3528	814	9	inagaki	inagaki	PROPN
fnp-3528	814	10	,	,	PUNCT
fnp-3528	814	11	n.	n.	NOUN
fnp-3528	814	12	;	;	PUNCT
fnp-3528	814	13	guan	guan	PROPN
fnp-3528	814	14	,	,	PUNCT
fnp-3528	814	15	j.	j.	PROPN
fnp-3528	814	16	;	;	PUNCT
fnp-3528	814	17	nakajo	nakajo	PROPN
fnp-3528	814	18	,	,	PUNCT
fnp-3528	814	19	s.	s.	PROPN
fnp-3528	814	20	;	;	PUNCT
fnp-3528	814	21	hirabayashi	hirabayashi	PROPN
fnp-3528	814	22	,	,	PUNCT
fnp-3528	814	23	t.	t.	PROPN
fnp-3528	814	24	;	;	PUNCT
fnp-3528	814	25	kikuyama	kikuyama	PROPN
fnp-3528	814	26	,	,	PUNCT
fnp-3528	814	27	s.	s.	PROPN
fnp-3528	814	28	;	;	PUNCT
fnp-3528	814	29	shioda	shioda	PROPN
fnp-3528	814	30	,	,	PUNCT
fnp-3528	814	31	s.	s.	PROPN
fnp-3528	814	32	atp	atp	PROPN
fnp-3528	814	33	-	-	PUNCT
fnp-3528	814	34	binding	bind	VERB
fnp-3528	814	35	cassette	cassette	NOUN
fnp-3528	814	36	transporter	transporter	NOUN
fnp-3528	814	37	abc2	abc2	PROPN
fnp-3528	814	38	/	/	PUNCT
fnp-3528	814	39	abca2	abca2	PROPN
fnp-3528	814	40	in	in	ADP
fnp-3528	814	41	the	the	DET
fnp-3528	814	42	rat	rat	NOUN
fnp-3528	814	43	brain	brain	NOUN
fnp-3528	814	44	:	:	PUNCT
fnp-3528	814	45	a	a	DET
fnp-3528	814	46	novel	novel	ADJ
fnp-3528	814	47	mammalian	mammalian	ADJ
fnp-3528	814	48	lysosome	lysosome	NOUN
fnp-3528	814	49	-	-	PUNCT
fnp-3528	814	50	associated	associate	VERB
fnp-3528	814	51	membrane	membrane	NOUN
fnp-3528	814	52	protein	protein	NOUN
fnp-3528	814	53	and	and	CCONJ
fnp-3528	814	54	a	a	DET
fnp-3528	814	55	specific	specific	ADJ
fnp-3528	814	56	marker	marker	NOUN
fnp-3528	814	57	for	for	ADP
fnp-3528	814	58	oligodendrocytes	oligodendrocyte	NOUN
fnp-3528	814	59	but	but	CCONJ
fnp-3528	814	60	not	not	PART
fnp-3528	814	61	for	for	ADP
fnp-3528	814	62	myelin	myelin	ADJ
fnp-3528	814	63	sheaths	sheath	NOUN
fnp-3528	814	64	.	.	PUNCT
fnp-3528	815	1	j	j	PROPN
fnp-3528	815	2	neurosci	neurosci	PROPN
fnp-3528	815	3	2001	2001	NUM
fnp-3528	815	4	,	,	PUNCT
fnp-3528	815	5	21	21	NUM
fnp-3528	815	6	,	,	PUNCT
fnp-3528	815	7	849	849	NUM
fnp-3528	815	8	-	-	SYM
fnp-3528	815	9	57	57	NUM
fnp-3528	815	10	.	.	PUNCT
fnp-3528	816	1	zhao	zhao	PROPN
fnp-3528	816	2	,	,	PUNCT
fnp-3528	816	3	l.	l.	PROPN
fnp-3528	816	4	x.	x.	PROPN
fnp-3528	816	5	;	;	PUNCT
fnp-3528	816	6	zhou	zhou	PROPN
fnp-3528	816	7	,	,	PUNCT
fnp-3528	816	8	c.	c.	PROPN
fnp-3528	816	9	j.	j.	PROPN
fnp-3528	816	10	;	;	PUNCT
fnp-3528	816	11	tanaka	tanaka	PROPN
fnp-3528	816	12	,	,	PUNCT
fnp-3528	816	13	a.	a.	NOUN
fnp-3528	816	14	;	;	PUNCT
fnp-3528	816	15	nakata	nakata	NOUN
fnp-3528	816	16	,	,	PUNCT
fnp-3528	816	17	m.	m.	NOUN
fnp-3528	816	18	;	;	PUNCT
fnp-3528	816	19	hirabayashi	hirabayashi	PROPN
fnp-3528	816	20	,	,	PUNCT
fnp-3528	816	21	t.	t.	PROPN
fnp-3528	816	22	;	;	PUNCT
fnp-3528	816	23	amachi	amachi	NOUN
fnp-3528	816	24	,	,	PUNCT
fnp-3528	816	25	t.	t.	PROPN
fnp-3528	816	26	;	;	PUNCT
fnp-3528	816	27	shioda	shioda	PROPN
fnp-3528	816	28	,	,	PUNCT
fnp-3528	816	29	s.	s.	PROPN
fnp-3528	816	30	;	;	PUNCT
fnp-3528	816	31	ueda	ueda	PROPN
fnp-3528	816	32	,	,	PUNCT
fnp-3528	816	33	k.	k.	PROPN
fnp-3528	816	34	;	;	PUNCT
fnp-3528	816	35	inagaki	inagaki	PROPN
fnp-3528	816	36	,	,	PUNCT
fnp-3528	816	37	n.	n.	NOUN
fnp-3528	816	38	cloning	cloning	NOUN
fnp-3528	816	39	,	,	PUNCT
fnp-3528	816	40	characterization	characterization	NOUN
fnp-3528	816	41	and	and	CCONJ
fnp-3528	816	42	tissue	tissue	NOUN
fnp-3528	816	43	distribution	distribution	NOUN
fnp-3528	816	44	of	of	ADP
fnp-3528	816	45	the	the	DET
fnp-3528	816	46	rat	rat	NOUN
fnp-3528	816	47	atp	atp	NOUN
fnp-3528	816	48	-	-	PUNCT
fnp-3528	816	49	binding	bind	VERB
fnp-3528	816	50	cassette	cassette	NOUN
fnp-3528	816	51	(	(	PUNCT
fnp-3528	816	52	abc	abc	PROPN
fnp-3528	816	53	)	)	PUNCT
fnp-3528	816	54	transporter	transporter	NOUN
fnp-3528	816	55	abc2	abc2	PROPN
fnp-3528	816	56	/	/	PUNCT
fnp-3528	816	57	abca2	abca2	PROPN
fnp-3528	816	58	.	.	PUNCT
fnp-3528	817	1	biochem	biochem	PROPN
fnp-3528	817	2	j	j	PROPN
fnp-3528	817	3	2000	2000	NUM
fnp-3528	817	4	,	,	PUNCT
fnp-3528	817	5	350	350	NUM
fnp-3528	817	6	pt	pt	NOUN
fnp-3528	817	7	3	3	NUM
fnp-3528	817	8	,	,	PUNCT
fnp-3528	817	9	865	865	NUM
fnp-3528	817	10	-	-	SYM
fnp-3528	817	11	72	72	NUM
fnp-3528	817	12	.	.	PUNCT
fnp-3528	818	1	tanaka	tanaka	PROPN
fnp-3528	818	2	,	,	PUNCT
fnp-3528	818	3	y.	y.	PROPN
fnp-3528	818	4	;	;	PUNCT
fnp-3528	818	5	yamada	yamada	PROPN
fnp-3528	818	6	,	,	PUNCT
fnp-3528	818	7	k.	k.	PROPN
fnp-3528	818	8	;	;	PUNCT
fnp-3528	818	9	zhou	zhou	PROPN
fnp-3528	818	10	,	,	PUNCT
fnp-3528	818	11	c.	c.	PROPN
fnp-3528	818	12	j.	j.	PROPN
fnp-3528	818	13	;	;	PUNCT
fnp-3528	818	14	ban	ban	NOUN
fnp-3528	818	15	,	,	PUNCT
fnp-3528	818	16	n.	n.	NOUN
fnp-3528	818	17	;	;	PUNCT
fnp-3528	818	18	shioda	shioda	PROPN
fnp-3528	818	19	,	,	PUNCT
fnp-3528	818	20	s.	s.	PROPN
fnp-3528	818	21	;	;	PUNCT
fnp-3528	818	22	inagaki	inagaki	PROPN
fnp-3528	818	23	,	,	PUNCT
fnp-3528	818	24	n.	n.	ADJ
fnp-3528	818	25	temporal	temporal	ADJ
fnp-3528	818	26	and	and	CCONJ
fnp-3528	818	27	spatial	spatial	ADJ
fnp-3528	818	28	profiles	profile	NOUN
fnp-3528	818	29	of	of	ADP
fnp-3528	818	30	abca2	abca2	NOUN
fnp-3528	818	31	-	-	PUNCT
fnp-3528	818	32	expressing	express	VERB
fnp-3528	818	33	oligodendrocytes	oligodendrocyte	NOUN
fnp-3528	818	34	in	in	ADP
fnp-3528	818	35	the	the	DET
fnp-3528	818	36	developing	develop	VERB
fnp-3528	818	37	rat	rat	NOUN
fnp-3528	818	38	brain	brain	NOUN
fnp-3528	818	39	.	.	PUNCT
fnp-3528	819	1	j	j	PROPN
fnp-3528	819	2	comp	comp	PROPN
fnp-3528	819	3	neurol	neurol	PROPN
fnp-3528	819	4	2003	2003	NUM
fnp-3528	819	5	,	,	PUNCT
fnp-3528	819	6	455	455	NUM
fnp-3528	819	7	,	,	PUNCT
fnp-3528	819	8	353	353	NUM
fnp-3528	819	9	-	-	SYM
fnp-3528	819	10	67	67	NUM
fnp-3528	819	11	.	.	PUNCT
fnp-3528	820	1	kaminski	kaminski	PROPN
fnp-3528	820	2	,	,	PUNCT
fnp-3528	820	3	w.	w.	PROPN
fnp-3528	820	4	e.	e.	PROPN
fnp-3528	820	5	;	;	PUNCT
fnp-3528	820	6	piehler	piehler	PROPN
fnp-3528	820	7	,	,	PUNCT
fnp-3528	820	8	a.	a.	NOUN
fnp-3528	820	9	;	;	PUNCT
fnp-3528	820	10	püllmann	püllmann	PROPN
fnp-3528	820	11	,	,	PUNCT
fnp-3528	820	12	k.	k.	PROPN
fnp-3528	820	13	;	;	PUNCT
fnp-3528	820	14	porsch	porsch	PROPN
fnp-3528	820	15	-	-	PUNCT
fnp-3528	820	16	ozcürümez	ozcürümez	PROPN
fnp-3528	820	17	,	,	PUNCT
fnp-3528	820	18	m.	m.	NOUN
fnp-3528	820	19	;	;	PUNCT
fnp-3528	820	20	duong	duong	PROPN
fnp-3528	820	21	,	,	PUNCT
fnp-3528	820	22	c.	c.	PROPN
fnp-3528	820	23	;	;	PUNCT
fnp-3528	820	24	bared	bare	VERB
fnp-3528	820	25	,	,	PUNCT
fnp-3528	820	26	g.	g.	PROPN
fnp-3528	820	27	m.	m.	NOUN
fnp-3528	820	28	;	;	PUNCT
fnp-3528	820	29	büchler	büchler	ADJ
fnp-3528	820	30	,	,	PUNCT
fnp-3528	820	31	c.	c.	PROPN
fnp-3528	820	32	;	;	PUNCT
fnp-3528	820	33	schmitz	schmitz	PROPN
fnp-3528	820	34	,	,	PUNCT
fnp-3528	820	35	g.	g.	PROPN
fnp-3528	820	36	complete	complete	ADJ
fnp-3528	820	37	coding	code	VERB
fnp-3528	820	38	sequence	sequence	NOUN
fnp-3528	820	39	,	,	PUNCT
fnp-3528	820	40	promoter	promoter	NOUN
fnp-3528	820	41	region	region	NOUN
fnp-3528	820	42	,	,	PUNCT
fnp-3528	820	43	and	and	CCONJ
fnp-3528	820	44	genomic	genomic	ADJ
fnp-3528	820	45	structure	structure	NOUN
fnp-3528	820	46	of	of	ADP
fnp-3528	820	47	the	the	DET
fnp-3528	820	48	human	human	ADJ
fnp-3528	820	49	abca2	abca2	NOUN
fnp-3528	820	50	gene	gene	NOUN
fnp-3528	820	51	and	and	CCONJ
fnp-3528	820	52	evidence	evidence	NOUN
fnp-3528	820	53	for	for	ADP
fnp-3528	820	54	sterol	sterol	NOUN
fnp-3528	820	55	-	-	PUNCT
fnp-3528	820	56	dependent	dependent	ADJ
fnp-3528	820	57	regulation	regulation	NOUN
fnp-3528	820	58	in	in	ADP
fnp-3528	820	59	macrophages	macrophage	NOUN
fnp-3528	820	60	.	.	PUNCT
fnp-3528	821	1	biochem	biochem	PROPN
fnp-3528	821	2	biophys	biophys	PROPN
fnp-3528	821	3	res	res	PROPN
fnp-3528	821	4	commun	commun	PROPN
fnp-3528	821	5	2001	2001	NUM
fnp-3528	821	6	,	,	PUNCT
fnp-3528	821	7	281	281	NUM
fnp-3528	821	8	,	,	PUNCT
fnp-3528	821	9	249	249	NUM
fnp-3528	821	10	-	-	SYM
fnp-3528	821	11	58	58	NUM
fnp-3528	821	12	.	.	PUNCT
fnp-3528	822	1	wollmer	wollmer	PROPN
fnp-3528	822	2	,	,	PUNCT
fnp-3528	822	3	m.	m.	NOUN
fnp-3528	822	4	a.	a.	PROPN
fnp-3528	822	5	;	;	PUNCT
fnp-3528	822	6	kapaki	kapaki	PROPN
fnp-3528	822	7	,	,	PUNCT
fnp-3528	822	8	e.	e.	PROPN
fnp-3528	822	9	;	;	PUNCT
fnp-3528	822	10	hersberger	hersberger	NOUN
fnp-3528	822	11	,	,	PUNCT
fnp-3528	822	12	m.	m.	NOUN
fnp-3528	822	13	;	;	PUNCT
fnp-3528	822	14	muntwyler	muntwyler	NOUN
fnp-3528	822	15	,	,	PUNCT
fnp-3528	822	16	j.	j.	PROPN
fnp-3528	822	17	;	;	PUNCT
fnp-3528	822	18	brunner	brunner	PROPN
fnp-3528	822	19	,	,	PUNCT
fnp-3528	822	20	f.	f.	PROPN
fnp-3528	822	21	;	;	PUNCT
fnp-3528	822	22	tsolaki	tsolaki	NOUN
fnp-3528	822	23	,	,	PUNCT
fnp-3528	822	24	m.	m.	NOUN
fnp-3528	822	25	;	;	PUNCT
fnp-3528	822	26	akatsu	akatsu	PROPN
fnp-3528	822	27	,	,	PUNCT
fnp-3528	822	28	h.	h.	PROPN
fnp-3528	822	29	;	;	PUNCT
fnp-3528	822	30	kosaka	kosaka	PROPN
fnp-3528	822	31	,	,	PUNCT
fnp-3528	822	32	k.	k.	PROPN
fnp-3528	822	33	;	;	PUNCT
fnp-3528	822	34	michikawa	michikawa	PROPN
fnp-3528	822	35	,	,	PUNCT
fnp-3528	822	36	m.	m.	NOUN
fnp-3528	822	37	;	;	PUNCT
fnp-3528	822	38	molyva	molyva	PROPN
fnp-3528	822	39	,	,	PUNCT
fnp-3528	822	40	d.	d.	PROPN
fnp-3528	822	41	;	;	PUNCT
fnp-3528	822	42	paraskevas	paraskevas	PROPN
fnp-3528	822	43	,	,	PUNCT
fnp-3528	822	44	g.	g.	PROPN
fnp-3528	822	45	p.	p.	PROPN
fnp-3528	822	46	;	;	PUNCT
fnp-3528	822	47	lütjohann	lütjohann	PROPN
fnp-3528	822	48	,	,	PUNCT
fnp-3528	822	49	d.	d.	PROPN
fnp-3528	822	50	;	;	PUNCT
fnp-3528	822	51	von	von	PROPN
fnp-3528	822	52	eckardstein	eckardstein	PROPN
fnp-3528	822	53	,	,	PUNCT
fnp-3528	822	54	a.	a.	NOUN
fnp-3528	822	55	;	;	PUNCT
fnp-3528	822	56	hock	hock	NOUN
fnp-3528	822	57	,	,	PUNCT
fnp-3528	822	58	c.	c.	PROPN
fnp-3528	822	59	;	;	PUNCT
fnp-3528	822	60	nitsch	nitsch	PROPN
fnp-3528	822	61	,	,	PUNCT
fnp-3528	822	62	r.	r.	PROPN
fnp-3528	822	63	m.	m.	NOUN
fnp-3528	822	64	;	;	PUNCT
fnp-3528	822	65	papassotiropoulos	papassotiropoulo	NOUN
fnp-3528	822	66	,	,	PUNCT
fnp-3528	822	67	a.	a.	NOUN
fnp-3528	822	68	ethnicity	ethnicity	NOUN
fnp-3528	822	69	-	-	PUNCT
fnp-3528	822	70	dependent	dependent	ADJ
fnp-3528	822	71	genetic	genetic	ADJ
fnp-3528	822	72	association	association	NOUN
fnp-3528	822	73	of	of	ADP
fnp-3528	822	74	abca2	abca2	NOUN
fnp-3528	822	75	with	with	ADP
fnp-3528	822	76	sporadic	sporadic	ADJ
fnp-3528	822	77	alzheimer	alzheimer	PROPN
fnp-3528	822	78	's	's	PART
fnp-3528	822	79	disease	disease	NOUN
fnp-3528	822	80	.	.	PUNCT
fnp-3528	823	1	am	be	AUX
fnp-3528	823	2	j	j	PROPN
fnp-3528	823	3	med	med	PROPN
fnp-3528	823	4	genet	genet	PROPN
fnp-3528	823	5	b	b	PROPN
fnp-3528	823	6	neuropsychiatr	neuropsychiatr	ADJ
fnp-3528	823	7	genet	genet	NOUN
fnp-3528	823	8	2006	2006	NUM
fnp-3528	823	9	,	,	PUNCT
fnp-3528	823	10	141b	141b	NOUN
fnp-3528	823	11	,	,	PUNCT
fnp-3528	823	12	534	534	NUM
fnp-3528	823	13	-	-	SYM
fnp-3528	823	14	6	6	NUM
fnp-3528	823	15	.	.	PUNCT
fnp-3528	824	1	minster	minster	PROPN
fnp-3528	824	2	,	,	PUNCT
fnp-3528	824	3	r.	r.	PROPN
fnp-3528	824	4	l.	l.	PROPN
fnp-3528	824	5	;	;	PUNCT
fnp-3528	824	6	dekosky	dekosky	PROPN
fnp-3528	824	7	,	,	PUNCT
fnp-3528	824	8	s.	s.	PROPN
fnp-3528	824	9	t.	t.	PROPN
fnp-3528	824	10	;	;	PUNCT
fnp-3528	824	11	kamboh	kamboh	PROPN
fnp-3528	824	12	,	,	PUNCT
fnp-3528	824	13	m.	m.	NOUN
fnp-3528	824	14	i.	i.	PROPN
fnp-3528	824	15	no	no	DET
fnp-3528	824	16	association	association	NOUN
fnp-3528	824	17	of	of	ADP
fnp-3528	824	18	dapk1	dapk1	NOUN
fnp-3528	824	19	and	and	CCONJ
fnp-3528	824	20	abca2	abca2	NOUN
fnp-3528	824	21	snps	snps	PROPN
fnp-3528	824	22	on	on	ADP
fnp-3528	824	23	chromosome	chromosome	NOUN
fnp-3528	824	24	9	9	NUM
fnp-3528	824	25	with	with	ADP
fnp-3528	824	26	alzheimer	alzheimer	PROPN
fnp-3528	824	27	's	's	PART
fnp-3528	824	28	disease	disease	NOUN
fnp-3528	824	29	.	.	PUNCT
fnp-3528	825	1	neurobiol	neurobiol	PROPN
fnp-3528	825	2	aging	age	VERB
fnp-3528	825	3	2009	2009	NUM
fnp-3528	825	4	,	,	PUNCT
fnp-3528	825	5	30	30	NUM
fnp-3528	825	6	,	,	PUNCT
fnp-3528	825	7	1890	1890	NUM
fnp-3528	825	8	-	-	SYM
fnp-3528	825	9	1	1	NUM
fnp-3528	825	10	.	.	PUNCT
fnp-3528	825	11	hu	hu	PROPN
fnp-3528	825	12	,	,	PUNCT
fnp-3528	825	13	w.	w.	PROPN
fnp-3528	825	14	;	;	PUNCT
fnp-3528	825	15	lin	lin	PROPN
fnp-3528	825	16	,	,	PUNCT
fnp-3528	825	17	x.	x.	PROPN
fnp-3528	825	18	;	;	PUNCT
fnp-3528	825	19	zhang	zhang	PROPN
fnp-3528	825	20	,	,	PUNCT
fnp-3528	825	21	h.	h.	PROPN
fnp-3528	825	22	;	;	PUNCT
fnp-3528	825	23	zhao	zhao	X
fnp-3528	825	24	,	,	PUNCT
fnp-3528	825	25	n.	n.	PROPN
fnp-3528	825	26	atp	atp	PROPN
fnp-3528	825	27	binding	bind	VERB
fnp-3528	825	28	cassette	cassette	NOUN
fnp-3528	825	29	subfamily	subfamily	ADV
fnp-3528	825	30	a	a	DET
fnp-3528	825	31	member	member	NOUN
fnp-3528	825	32	2	2	NUM
fnp-3528	825	33	(	(	PUNCT
fnp-3528	825	34	abca2	abca2	NOUN
fnp-3528	825	35	)	)	PUNCT
fnp-3528	825	36	expression	expression	NOUN
fnp-3528	825	37	and	and	CCONJ
fnp-3528	825	38	methylation	methylation	NOUN
fnp-3528	825	39	are	be	AUX
fnp-3528	825	40	associated	associate	VERB
fnp-3528	825	41	with	with	ADP
fnp-3528	825	42	alzheimer	alzheimer	PROPN
fnp-3528	825	43	's	's	PART
fnp-3528	825	44	disease	disease	NOUN
fnp-3528	825	45	.	.	PUNCT
fnp-3528	826	1	med	med	PROPN
fnp-3528	826	2	sci	sci	PROPN
fnp-3528	826	3	monit	monit	PROPN
fnp-3528	826	4	2017	2017	NUM
fnp-3528	826	5	,	,	PUNCT
fnp-3528	826	6	23	23	NUM
fnp-3528	826	7	,	,	PUNCT
fnp-3528	826	8	5851	5851	NUM
fnp-3528	826	9	-	-	SYM
fnp-3528	826	10	61	61	NUM
fnp-3528	826	11	.	.	PUNCT
fnp-3528	827	1	davis	davis	PROPN
fnp-3528	827	2	,	,	PUNCT
fnp-3528	827	3	w.	w.	PROPN
fnp-3528	827	4	,	,	PUNCT
fnp-3528	827	5	jr	jr	PROPN
fnp-3528	827	6	.	.	PROPN
fnp-3528	827	7	;	;	PUNCT
fnp-3528	827	8	boyd	boyd	PROPN
fnp-3528	827	9	,	,	PUNCT
fnp-3528	827	10	j.	j.	PROPN
fnp-3528	827	11	t.	t.	PROPN
fnp-3528	827	12	;	;	PUNCT
fnp-3528	827	13	ile	ile	PROPN
fnp-3528	827	14	,	,	PUNCT
fnp-3528	827	15	k.	k.	PROPN
fnp-3528	827	16	e.	e.	PROPN
fnp-3528	827	17	;	;	PUNCT
fnp-3528	827	18	tew	tew	PROPN
fnp-3528	827	19	,	,	PUNCT
fnp-3528	827	20	k.	k.	PROPN
fnp-3528	827	21	d.	d.	PROPN
fnp-3528	827	22	human	human	PROPN
fnp-3528	827	23	atp	atp	PROPN
fnp-3528	827	24	-	-	PUNCT
fnp-3528	827	25	binding	bind	VERB
fnp-3528	827	26	cassette	cassette	NOUN
fnp-3528	827	27	transporter-2	transporter-2	NUM
fnp-3528	827	28	(	(	PUNCT
fnp-3528	827	29	abca2	abca2	PROPN
fnp-3528	827	30	)	)	PUNCT
fnp-3528	827	31	positively	positively	ADV
fnp-3528	827	32	regulates	regulate	VERB
fnp-3528	827	33	low	low	ADJ
fnp-3528	827	34	-	-	PUNCT
fnp-3528	827	35	density	density	NOUN
fnp-3528	827	36	lipoprotein	lipoprotein	ADJ
fnp-3528	827	37	receptor	receptor	NOUN
fnp-3528	827	38	expression	expression	NOUN
fnp-3528	827	39	and	and	CCONJ
fnp-3528	827	40	negatively	negatively	ADV
fnp-3528	827	41	regulates	regulate	VERB
fnp-3528	827	42	cholesterol	cholesterol	NOUN
fnp-3528	827	43	esterification	esterification	NOUN
fnp-3528	827	44	in	in	ADP
fnp-3528	827	45	chinese	chinese	ADJ
fnp-3528	827	46	hamster	hamster	NOUN
fnp-3528	827	47	ovary	ovary	ADJ
fnp-3528	827	48	cells	cell	NOUN
fnp-3528	827	49	.	.	PUNCT
fnp-3528	828	1	biochim	biochim	PROPN
fnp-3528	828	2	biophys	biophy	NOUN
fnp-3528	828	3	acta	acta	PROPN
fnp-3528	828	4	2004	2004	NUM
fnp-3528	828	5	,	,	PUNCT
fnp-3528	828	6	1683	1683	NUM
fnp-3528	828	7	,	,	PUNCT
fnp-3528	828	8	89	89	NUM
fnp-3528	828	9	-	-	SYM
fnp-3528	828	10	100	100	NUM
fnp-3528	828	11	.	.	PUNCT
fnp-3528	829	1	chen	chen	PROPN
fnp-3528	829	2	,	,	PUNCT
fnp-3528	829	3	z.	z.	PROPN
fnp-3528	829	4	j.	j.	PROPN
fnp-3528	829	5	;	;	PUNCT
fnp-3528	829	6	vulevic	vulevic	PROPN
fnp-3528	829	7	,	,	PUNCT
fnp-3528	829	8	b.	b.	PROPN
fnp-3528	829	9	;	;	PUNCT
fnp-3528	829	10	ile	ile	PROPN
fnp-3528	829	11	,	,	PUNCT
fnp-3528	829	12	k.	k.	PROPN
fnp-3528	829	13	e.	e.	PROPN
fnp-3528	829	14	;	;	PUNCT
fnp-3528	829	15	soulika	soulika	PROPN
fnp-3528	829	16	,	,	PUNCT
fnp-3528	829	17	a.	a.	PROPN
fnp-3528	829	18	;	;	PUNCT
fnp-3528	829	19	davis	davis	PROPN
fnp-3528	829	20	,	,	PUNCT
fnp-3528	829	21	w.	w.	PROPN
fnp-3528	829	22	,	,	PUNCT
fnp-3528	829	23	jr	jr	PROPN
fnp-3528	829	24	.	.	PROPN
fnp-3528	829	25	;	;	PUNCT
fnp-3528	829	26	reiner	reiner	NOUN
fnp-3528	829	27	,	,	PUNCT
fnp-3528	829	28	p.	p.	PROPN
fnp-3528	829	29	b.	b.	PROPN
fnp-3528	829	30	;	;	PUNCT
fnp-3528	829	31	connop	connop	PROPN
fnp-3528	829	32	,	,	PUNCT
fnp-3528	829	33	b.	b.	PROPN
fnp-3528	829	34	p.	p.	PROPN
fnp-3528	829	35	;	;	PUNCT
fnp-3528	829	36	nathwani	nathwani	PROPN
fnp-3528	829	37	,	,	PUNCT
fnp-3528	829	38	p.	p.	NOUN
fnp-3528	829	39	;	;	PUNCT
fnp-3528	829	40	trojanowski	trojanowski	PROPN
fnp-3528	829	41	,	,	PUNCT
fnp-3528	829	42	j.	j.	PROPN
fnp-3528	829	43	q.	q.	PROPN
fnp-3528	829	44	;	;	PUNCT
fnp-3528	829	45	tew	tew	PROPN
fnp-3528	829	46	,	,	PUNCT
fnp-3528	829	47	k.	k.	PROPN
fnp-3528	829	48	d.	d.	PROPN
fnp-3528	829	49	association	association	PROPN
fnp-3528	829	50	of	of	ADP
fnp-3528	829	51	abca2	abca2	NOUN
fnp-3528	829	52	expression	expression	NOUN
fnp-3528	829	53	with	with	ADP
fnp-3528	829	54	determinants	determinant	NOUN
fnp-3528	829	55	of	of	ADP
fnp-3528	829	56	alzheimer	alzheimer	PROPN
fnp-3528	829	57	's	's	PART
fnp-3528	829	58	disease	disease	NOUN
fnp-3528	829	59	.	.	PUNCT
fnp-3528	830	1	faseb	faseb	PROPN
fnp-3528	830	2	j	j	PROPN
fnp-3528	830	3	2004	2004	NUM
fnp-3528	830	4	,	,	PUNCT
fnp-3528	830	5	18	18	NUM
fnp-3528	830	6	,	,	PUNCT
fnp-3528	830	7	1129	1129	NUM
fnp-3528	830	8	-	-	SYM
fnp-3528	830	9	31	31	NUM
fnp-3528	830	10	.	.	PUNCT
fnp-3528	831	1	katsouri	katsouri	PROPN
fnp-3528	831	2	,	,	PUNCT
fnp-3528	831	3	l.	l.	PROPN
fnp-3528	831	4	;	;	PUNCT
fnp-3528	831	5	georgopoulos	georgopoulo	NOUN
fnp-3528	831	6	,	,	PUNCT
fnp-3528	831	7	s.	s.	PROPN
fnp-3528	831	8	lack	lack	NOUN
fnp-3528	831	9	of	of	ADP
fnp-3528	831	10	ldl	ldl	NOUN
fnp-3528	831	11	receptor	receptor	NOUN
fnp-3528	831	12	enhances	enhance	VERB
fnp-3528	831	13	amyloid	amyloid	NOUN
fnp-3528	831	14	deposition	deposition	NOUN
fnp-3528	831	15	and	and	CCONJ
fnp-3528	831	16	decreases	decrease	VERB
fnp-3528	831	17	glial	glial	ADJ
fnp-3528	831	18	response	response	NOUN
fnp-3528	831	19	in	in	ADP
fnp-3528	831	20	an	an	DET
fnp-3528	831	21	alzheimer	alzheimer	NOUN
fnp-3528	831	22	's	's	PART
fnp-3528	831	23	disease	disease	NOUN
fnp-3528	831	24	mouse	mouse	NOUN
fnp-3528	831	25	model	model	NOUN
fnp-3528	831	26	.	.	PUNCT
fnp-3528	832	1	plos	plos	PROPN
fnp-3528	832	2	one	one	NUM
fnp-3528	832	3	2011	2011	NUM
fnp-3528	832	4	,	,	PUNCT
fnp-3528	832	5	6	6	NUM
fnp-3528	832	6	,	,	PUNCT
fnp-3528	832	7	e21880	e21880	NOUN
fnp-3528	832	8	.	.	X
fnp-3528	833	1	michaki	michaki	AUX
fnp-3528	833	2	,	,	PUNCT
fnp-3528	833	3	v.	v.	ADV
fnp-3528	833	4	;	;	PUNCT
fnp-3528	833	5	guix	guix	NOUN
fnp-3528	833	6	,	,	PUNCT
fnp-3528	833	7	f.	f.	PROPN
fnp-3528	833	8	x.	x.	PROPN
fnp-3528	833	9	;	;	PUNCT
fnp-3528	833	10	vennekens	venneken	NOUN
fnp-3528	833	11	,	,	PUNCT
fnp-3528	833	12	k.	k.	PROPN
fnp-3528	833	13	;	;	PUNCT
fnp-3528	833	14	munck	munck	PROPN
fnp-3528	833	15	,	,	PUNCT
fnp-3528	833	16	s.	s.	PROPN
fnp-3528	833	17	;	;	PUNCT
fnp-3528	833	18	dingwall	dingwall	PROPN
fnp-3528	833	19	,	,	PUNCT
fnp-3528	833	20	c.	c.	PROPN
fnp-3528	833	21	;	;	PUNCT
fnp-3528	833	22	davis	davis	PROPN
fnp-3528	833	23	,	,	PUNCT
fnp-3528	833	24	j.	j.	PROPN
fnp-3528	833	25	b.	b.	PROPN
fnp-3528	833	26	;	;	PUNCT
fnp-3528	833	27	townsend	townsend	PROPN
fnp-3528	833	28	,	,	PUNCT
fnp-3528	833	29	d.	d.	PROPN
fnp-3528	833	30	m.	m.	PROPN
fnp-3528	833	31	;	;	PUNCT
fnp-3528	833	32	tew	tew	PROPN
fnp-3528	833	33	,	,	PUNCT
fnp-3528	833	34	k.	k.	PROPN
fnp-3528	833	35	d.	d.	PROPN
fnp-3528	833	36	;	;	PUNCT
fnp-3528	833	37	feiguin	feiguin	PROPN
fnp-3528	833	38	,	,	PUNCT
fnp-3528	833	39	f.	f.	PROPN
fnp-3528	833	40	;	;	PUNCT
fnp-3528	833	41	de	de	PROPN
fnp-3528	833	42	strooper	strooper	PROPN
fnp-3528	833	43	,	,	PUNCT
fnp-3528	833	44	b.	b.	PROPN
fnp-3528	833	45	;	;	PUNCT
fnp-3528	833	46	dotti	dotti	PROPN
fnp-3528	833	47	,	,	PUNCT
fnp-3528	833	48	c.	c.	PROPN
fnp-3528	833	49	g.	g.	PROPN
fnp-3528	833	50	;	;	PUNCT
fnp-3528	833	51	wahle	wahle	ADJ
fnp-3528	833	52	,	,	PUNCT
fnp-3528	833	53	t.	t.	NOUN
fnp-3528	833	54	down	down	ADP
fnp-3528	833	55	-	-	PUNCT
fnp-3528	833	56	regulation	regulation	NOUN
fnp-3528	833	57	of	of	ADP
fnp-3528	833	58	the	the	DET
fnp-3528	833	59	atp	atp	NOUN
fnp-3528	833	60	-	-	PUNCT
fnp-3528	833	61	binding	bind	VERB
fnp-3528	833	62	cassette	cassette	NOUN
fnp-3528	833	63	transporter	transporter	NOUN
fnp-3528	833	64	2	2	NUM
fnp-3528	833	65	(	(	PUNCT
fnp-3528	833	66	abca2	abca2	NOUN
fnp-3528	833	67	)	)	PUNCT
fnp-3528	833	68	reduces	reduce	VERB
fnp-3528	833	69	amyloid	amyloid	NOUN
fnp-3528	833	70	-	-	PUNCT
fnp-3528	833	71	beta	beta	NOUN
fnp-3528	833	72	production	production	NOUN
fnp-3528	833	73	by	by	ADP
fnp-3528	833	74	altering	alter	VERB
fnp-3528	833	75	nicastrin	nicastrin	ADJ
fnp-3528	833	76	maturation	maturation	NOUN
fnp-3528	833	77	and	and	CCONJ
fnp-3528	833	78	intracellular	intracellular	ADJ
fnp-3528	833	79	localization	localization	NOUN
fnp-3528	833	80	.	.	PUNCT
fnp-3528	834	1	j	j	PROPN
fnp-3528	834	2	biol	biol	PROPN
fnp-3528	834	3	chem	chem	NOUN
fnp-3528	834	4	2012	2012	NUM
fnp-3528	834	5	,	,	PUNCT
fnp-3528	834	6	287	287	NUM
fnp-3528	834	7	,	,	PUNCT
fnp-3528	834	8	1100	1100	NUM
fnp-3528	834	9	-	-	SYM
fnp-3528	834	10	11	11	NUM
fnp-3528	834	11	.	.	PUNCT
fnp-3528	835	1	davis	davis	PROPN
fnp-3528	835	2	,	,	PUNCT
fnp-3528	835	3	w.	w.	PROPN
fnp-3528	835	4	,	,	PUNCT
fnp-3528	835	5	jr	jr	PROPN
fnp-3528	835	6	.	.	PUNCT
fnp-3528	836	1	the	the	DET
fnp-3528	836	2	atp	atp	NOUN
fnp-3528	836	3	-	-	PUNCT
fnp-3528	836	4	binding	bind	VERB
fnp-3528	836	5	cassette	cassette	NOUN
fnp-3528	836	6	transporter-2	transporter-2	NUM
fnp-3528	836	7	(	(	PUNCT
fnp-3528	836	8	abca2	abca2	NOUN
fnp-3528	836	9	)	)	PUNCT
fnp-3528	836	10	overexpression	overexpression	NOUN
fnp-3528	836	11	modulates	modulate	NOUN
fnp-3528	836	12	sphingosine	sphingosine	NOUN
fnp-3528	836	13	levels	level	NOUN
fnp-3528	836	14	and	and	CCONJ
fnp-3528	836	15	transcription	transcription	NOUN
fnp-3528	836	16	of	of	ADP
fnp-3528	836	17	the	the	DET
fnp-3528	836	18	amyloid	amyloid	NOUN
fnp-3528	836	19	precursor	precursor	NOUN
fnp-3528	836	20	protein	protein	NOUN
fnp-3528	836	21	(	(	PUNCT
fnp-3528	836	22	app	app	NOUN
fnp-3528	836	23	)	)	PUNCT
fnp-3528	836	24	gene	gene	NOUN
fnp-3528	836	25	.	.	PUNCT
fnp-3528	837	1	curr	curr	PROPN
fnp-3528	837	2	alzheimer	alzheimer	PROPN
fnp-3528	837	3	res	res	PROPN
fnp-3528	837	4	2015	2015	NUM
fnp-3528	837	5	,	,	PUNCT
fnp-3528	837	6	12	12	NUM
fnp-3528	837	7	,	,	PUNCT
fnp-3528	837	8	847	847	NUM
fnp-3528	837	9	-	-	SYM
fnp-3528	837	10	59	59	NUM
fnp-3528	837	11	.	.	PUNCT
fnp-3528	838	1	kim	kim	PROPN
fnp-3528	838	2	,	,	PUNCT
fnp-3528	838	3	w.	w.	PROPN
fnp-3528	838	4	s.	s.	PROPN
fnp-3528	838	5	;	;	PUNCT
fnp-3528	838	6	rahmanto	rahmanto	NOUN
fnp-3528	838	7	,	,	PUNCT
fnp-3528	838	8	a.	a.	NOUN
fnp-3528	838	9	s.	s.	PROPN
fnp-3528	838	10	;	;	PUNCT
fnp-3528	838	11	kamili	kamili	PROPN
fnp-3528	838	12	,	,	PUNCT
fnp-3528	838	13	a.	a.	NOUN
fnp-3528	838	14	;	;	PUNCT
fnp-3528	838	15	rye	rye	PROPN
fnp-3528	838	16	,	,	PUNCT
fnp-3528	838	17	k.	k.	PROPN
fnp-3528	838	18	a.	a.	PROPN
fnp-3528	838	19	;	;	PUNCT
fnp-3528	838	20	guillemin	guillemin	PROPN
fnp-3528	838	21	,	,	PUNCT
fnp-3528	838	22	g.	g.	PROPN
fnp-3528	838	23	j.	j.	PROPN
fnp-3528	838	24	;	;	PUNCT
fnp-3528	838	25	gelissen	gelissen	PROPN
fnp-3528	838	26	,	,	PUNCT
fnp-3528	838	27	i.	i.	PROPN
fnp-3528	838	28	c.	c.	PROPN
fnp-3528	838	29	;	;	PUNCT
fnp-3528	838	30	jessup	jessup	PROPN
fnp-3528	838	31	,	,	PUNCT
fnp-3528	838	32	w.	w.	PROPN
fnp-3528	838	33	;	;	PUNCT
fnp-3528	838	34	hill	hill	PROPN
fnp-3528	838	35	,	,	PUNCT
fnp-3528	838	36	a.	a.	PROPN
fnp-3528	838	37	f.	f.	PROPN
fnp-3528	838	38	;	;	PUNCT
fnp-3528	838	39	garner	garner	PROPN
fnp-3528	838	40	,	,	PUNCT
fnp-3528	838	41	b.	b.	PROPN
fnp-3528	838	42	role	role	NOUN
fnp-3528	838	43	of	of	ADP
fnp-3528	838	44	abcg1	abcg1	ADV
fnp-3528	838	45	and	and	CCONJ
fnp-3528	838	46	abca1	abca1	NOUN
fnp-3528	838	47	in	in	ADP
fnp-3528	838	48	regulation	regulation	NOUN
fnp-3528	838	49	of	of	ADP
fnp-3528	838	50	neuronal	neuronal	ADJ
fnp-3528	838	51	cholesterol	cholesterol	NOUN
fnp-3528	838	52	efflux	efflux	VERB
fnp-3528	838	53	to	to	PART
fnp-3528	838	54	apolipoprotein	apolipoprotein	VERB
fnp-3528	838	55	e	e	ADP
fnp-3528	838	56	discs	disc	NOUN
fnp-3528	838	57	and	and	CCONJ
fnp-3528	838	58	suppression	suppression	NOUN
fnp-3528	838	59	of	of	ADP
fnp-3528	838	60	amyloid	amyloid	NOUN
fnp-3528	838	61	-	-	PUNCT
fnp-3528	838	62	beta	beta	NOUN
fnp-3528	838	63	peptide	peptide	NOUN
fnp-3528	838	64	generation	generation	NOUN
fnp-3528	838	65	.	.	PUNCT
fnp-3528	839	1	j	j	PROPN
fnp-3528	839	2	biol	biol	PROPN
fnp-3528	839	3	chem	chem	NOUN
fnp-3528	839	4	2007	2007	NUM
fnp-3528	839	5	,	,	PUNCT
fnp-3528	839	6	282	282	NUM
fnp-3528	839	7	,	,	PUNCT
fnp-3528	839	8	2851	2851	NUM
fnp-3528	839	9	-	-	SYM
fnp-3528	839	10	61	61	NUM
fnp-3528	839	11	.	.	PUNCT
fnp-3528	840	1	yamano	yamano	PROPN
fnp-3528	840	2	,	,	PUNCT
fnp-3528	840	3	g.	g.	PROPN
fnp-3528	840	4	;	;	PUNCT
fnp-3528	840	5	funahashi	funahashi	PROPN
fnp-3528	840	6	,	,	PUNCT
fnp-3528	840	7	h.	h.	PROPN
fnp-3528	840	8	;	;	PUNCT
fnp-3528	840	9	kawanami	kawanami	NOUN
fnp-3528	840	10	,	,	PUNCT
fnp-3528	840	11	o.	o.	PROPN
fnp-3528	840	12	;	;	PUNCT
fnp-3528	840	13	zhao	zhao	PROPN
fnp-3528	840	14	,	,	PUNCT
fnp-3528	840	15	l.	l.	PROPN
fnp-3528	840	16	x.	x.	PROPN
fnp-3528	840	17	;	;	PUNCT
fnp-3528	840	18	ban	ban	NOUN
fnp-3528	840	19	,	,	PUNCT
fnp-3528	840	20	n.	n.	PROPN
fnp-3528	840	21	;	;	PUNCT
fnp-3528	840	22	uchida	uchida	PROPN
fnp-3528	840	23	,	,	PUNCT
fnp-3528	840	24	y.	y.	PROPN
fnp-3528	840	25	;	;	PUNCT
fnp-3528	840	26	morohoshi	morohoshi	NOUN
fnp-3528	840	27	,	,	PUNCT
fnp-3528	840	28	t.	t.	PROPN
fnp-3528	840	29	;	;	PUNCT
fnp-3528	840	30	ogawa	ogawa	PROPN
fnp-3528	840	31	,	,	PUNCT
fnp-3528	840	32	j.	j.	PROPN
fnp-3528	840	33	;	;	PUNCT
fnp-3528	840	34	shioda	shioda	PROPN
fnp-3528	840	35	,	,	PUNCT
fnp-3528	840	36	s.	s.	PROPN
fnp-3528	840	37	;	;	PUNCT
fnp-3528	840	38	inagaki	inagaki	PROPN
fnp-3528	840	39	,	,	PUNCT
fnp-3528	840	40	n.	n.	PROPN
fnp-3528	840	41	abca3	abca3	PROPN
fnp-3528	840	42	is	be	AUX
fnp-3528	840	43	a	a	DET
fnp-3528	840	44	lamellar	lamellar	ADJ
fnp-3528	840	45	body	body	NOUN
fnp-3528	840	46	membrane	membrane	NOUN
fnp-3528	840	47	protein	protein	NOUN
fnp-3528	840	48	in	in	ADP
fnp-3528	840	49	human	human	ADJ
fnp-3528	840	50	lung	lung	NOUN
fnp-3528	840	51	alveolar	alveolar	ADJ
fnp-3528	840	52	type	type	NOUN
fnp-3528	840	53	ii	ii	NOUN
fnp-3528	840	54	cells	cell	NOUN
fnp-3528	840	55	.	.	PUNCT
fnp-3528	841	1	febs	febs	PROPN
fnp-3528	841	2	lett	lett	PROPN
fnp-3528	841	3	2001	2001	NUM
fnp-3528	841	4	,	,	PUNCT
fnp-3528	841	5	508	508	NUM
fnp-3528	841	6	,	,	PUNCT
fnp-3528	841	7	221	221	NUM
fnp-3528	841	8	-	-	SYM
fnp-3528	841	9	5	5	NUM
fnp-3528	841	10	.	.	PUNCT
fnp-3528	841	11	fitzgerald	fitzgerald	PROPN
fnp-3528	841	12	,	,	PUNCT
fnp-3528	841	13	m.	m.	PROPN
fnp-3528	841	14	l.	l.	PROPN
fnp-3528	841	15	;	;	PUNCT
fnp-3528	841	16	xavier	xavier	PROPN
fnp-3528	841	17	,	,	PUNCT
fnp-3528	841	18	r.	r.	PROPN
fnp-3528	841	19	;	;	PUNCT
fnp-3528	841	20	haley	haley	NOUN
fnp-3528	841	21	,	,	PUNCT
fnp-3528	841	22	k.	k.	PROPN
fnp-3528	841	23	j.	j.	PROPN
fnp-3528	841	24	;	;	PUNCT
fnp-3528	841	25	welti	welti	PROPN
fnp-3528	841	26	,	,	PUNCT
fnp-3528	841	27	r.	r.	PROPN
fnp-3528	841	28	;	;	PUNCT
fnp-3528	841	29	goss	goss	PROPN
fnp-3528	841	30	,	,	PUNCT
fnp-3528	841	31	j.	j.	PROPN
fnp-3528	841	32	l.	l.	PROPN
fnp-3528	841	33	;	;	PUNCT
fnp-3528	841	34	brown	brown	PROPN
fnp-3528	841	35	,	,	PUNCT
fnp-3528	841	36	c.	c.	PROPN
fnp-3528	841	37	e.	e.	PROPN
fnp-3528	841	38	;	;	PUNCT
fnp-3528	841	39	zhuang	zhuang	PROPN
fnp-3528	841	40	,	,	PUNCT
fnp-3528	841	41	d.	d.	PROPN
fnp-3528	841	42	z.	z.	PROPN
fnp-3528	841	43	;	;	PUNCT
fnp-3528	841	44	bell	bell	PROPN
fnp-3528	841	45	,	,	PUNCT
fnp-3528	841	46	s.	s.	PROPN
fnp-3528	841	47	a.	a.	PROPN
fnp-3528	841	48	;	;	PUNCT
fnp-3528	841	49	lu	lu	PROPN
fnp-3528	841	50	,	,	PUNCT
fnp-3528	841	51	n.	n.	PROPN
fnp-3528	841	52	;	;	PUNCT
fnp-3528	841	53	mckee	mckee	PROPN
fnp-3528	841	54	,	,	PUNCT
fnp-3528	841	55	m.	m.	NOUN
fnp-3528	841	56	;	;	PUNCT
fnp-3528	841	57	seed	seed	NOUN
fnp-3528	841	58	,	,	PUNCT
fnp-3528	841	59	b.	b.	PROPN
fnp-3528	841	60	;	;	PUNCT
fnp-3528	841	61	freeman	freeman	PROPN
fnp-3528	841	62	,	,	PUNCT
fnp-3528	841	63	m.	m.	NOUN
fnp-3528	841	64	w.	w.	PROPN
fnp-3528	841	65	abca3	abca3	PROPN
fnp-3528	841	66	inactivation	inactivation	NOUN
fnp-3528	841	67	in	in	ADP
fnp-3528	841	68	mice	mouse	NOUN
fnp-3528	841	69	causes	cause	VERB
fnp-3528	841	70	respiratory	respiratory	ADJ
fnp-3528	841	71	failure	failure	NOUN
fnp-3528	841	72	,	,	PUNCT
fnp-3528	841	73	loss	loss	NOUN
fnp-3528	841	74	of	of	ADP
fnp-3528	841	75	pulmonary	pulmonary	ADJ
fnp-3528	841	76	surfactant	surfactant	NOUN
fnp-3528	841	77	,	,	PUNCT
fnp-3528	841	78	and	and	CCONJ
fnp-3528	841	79	depletion	depletion	NOUN
fnp-3528	841	80	of	of	ADP
fnp-3528	841	81	lung	lung	NOUN
fnp-3528	841	82	phosphatidylglycerol	phosphatidylglycerol	NOUN
fnp-3528	841	83	.	.	PUNCT
fnp-3528	842	1	j	j	PROPN
fnp-3528	842	2	lipid	lipid	PROPN
fnp-3528	842	3	res	re	NOUN
fnp-3528	842	4	2007	2007	NUM
fnp-3528	842	5	,	,	PUNCT
fnp-3528	842	6	48	48	NUM
fnp-3528	842	7	,	,	PUNCT
fnp-3528	842	8	621	621	NUM
fnp-3528	842	9	-	-	SYM
fnp-3528	842	10	32	32	NUM
fnp-3528	843	1	.	.	PUNCT
fnp-3528	843	2	stahlman	stahlman	PROPN
fnp-3528	843	3	,	,	PUNCT
fnp-3528	843	4	m.	m.	NOUN
fnp-3528	843	5	t.	t.	PROPN
fnp-3528	843	6	;	;	PUNCT
fnp-3528	843	7	besnard	besnard	PROPN
fnp-3528	843	8	,	,	PUNCT
fnp-3528	843	9	v.	v.	ADV
fnp-3528	843	10	;	;	PUNCT
fnp-3528	843	11	wert	wert	PROPN
fnp-3528	843	12	,	,	PUNCT
fnp-3528	843	13	s.	s.	PROPN
fnp-3528	843	14	e.	e.	PROPN
fnp-3528	843	15	;	;	PUNCT
fnp-3528	843	16	weaver	weaver	PROPN
fnp-3528	843	17	,	,	PUNCT
fnp-3528	843	18	t.	t.	PROPN
fnp-3528	843	19	e.	e.	PROPN
fnp-3528	843	20	;	;	PUNCT
fnp-3528	843	21	dingle	dingle	PROPN
fnp-3528	843	22	,	,	PUNCT
fnp-3528	843	23	s.	s.	PROPN
fnp-3528	843	24	;	;	PUNCT
fnp-3528	843	25	xu	xu	PROPN
fnp-3528	843	26	,	,	PUNCT
fnp-3528	843	27	y.	y.	PROPN
fnp-3528	843	28	;	;	PUNCT
fnp-3528	843	29	von	von	PROPN
fnp-3528	843	30	zychlin	zychlin	PROPN
fnp-3528	843	31	,	,	PUNCT
fnp-3528	843	32	k.	k.	PROPN
fnp-3528	843	33	;	;	PUNCT
fnp-3528	843	34	olson	olson	PROPN
fnp-3528	843	35	,	,	PUNCT
fnp-3528	843	36	s.	s.	PROPN
fnp-3528	843	37	j.	j.	PROPN
fnp-3528	843	38	;	;	PUNCT
fnp-3528	843	39	whitsett	whitsett	PROPN
fnp-3528	843	40	,	,	PUNCT
fnp-3528	843	41	j.	j.	PROPN
fnp-3528	843	42	a.	a.	NOUN
fnp-3528	843	43	expression	expression	NOUN
fnp-3528	843	44	of	of	ADP
fnp-3528	843	45	abca3	abca3	PROPN
fnp-3528	843	46	in	in	ADP
fnp-3528	843	47	developing	develop	VERB
fnp-3528	843	48	lung	lung	NOUN
fnp-3528	843	49	and	and	CCONJ
fnp-3528	843	50	other	other	ADJ
fnp-3528	843	51	tissues	tissue	NOUN
fnp-3528	843	52	.	.	PUNCT
fnp-3528	844	1	j	j	PROPN
fnp-3528	844	2	histochem	histochem	PROPN
fnp-3528	844	3	cytochem	cytochem	PROPN
fnp-3528	844	4	2007	2007	NUM
fnp-3528	844	5	,	,	PUNCT
fnp-3528	844	6	55	55	NUM
fnp-3528	844	7	,	,	PUNCT
fnp-3528	844	8	71	71	NUM
fnp-3528	844	9	-	-	SYM
fnp-3528	844	10	83	83	NUM
fnp-3528	844	11	.	.	PUNCT
fnp-3528	845	1	kim	kim	PROPN
fnp-3528	845	2	,	,	PUNCT
fnp-3528	845	3	w.	w.	PROPN
fnp-3528	845	4	s.	s.	PROPN
fnp-3528	845	5	;	;	PUNCT
fnp-3528	845	6	guillemin	guillemin	PROPN
fnp-3528	845	7	,	,	PUNCT
fnp-3528	845	8	g.	g.	PROPN
fnp-3528	845	9	j.	j.	PROPN
fnp-3528	845	10	;	;	PUNCT
fnp-3528	845	11	glaros	glaros	PROPN
fnp-3528	845	12	,	,	PUNCT
fnp-3528	845	13	e.	e.	PROPN
fnp-3528	845	14	n.	n.	PROPN
fnp-3528	845	15	;	;	PUNCT
fnp-3528	845	16	lim	lim	PROPN
fnp-3528	845	17	,	,	PUNCT
fnp-3528	845	18	c.	c.	PROPN
fnp-3528	845	19	k.	k.	PROPN
fnp-3528	845	20	;	;	PUNCT
fnp-3528	845	21	garner	garner	PROPN
fnp-3528	845	22	,	,	PUNCT
fnp-3528	845	23	b.	b.	PROPN
fnp-3528	845	24	quantitation	quantitation	PROPN
fnp-3528	845	25	of	of	ADP
fnp-3528	845	26	atp	atp	PROPN
fnp-3528	845	27	-	-	PUNCT
fnp-3528	845	28	binding	bind	VERB
fnp-3528	845	29	cassette	cassette	NOUN
fnp-3528	845	30	subfamily	subfamily	ADV
fnp-3528	845	31	-	-	PUNCT
fnp-3528	845	32	a	a	DET
fnp-3528	845	33	transporter	transporter	NOUN
fnp-3528	845	34	gene	gene	NOUN
fnp-3528	845	35	expression	expression	NOUN
fnp-3528	845	36	in	in	ADP
fnp-3528	845	37	primary	primary	ADJ
fnp-3528	845	38	human	human	ADJ
fnp-3528	845	39	brain	brain	NOUN
fnp-3528	845	40	cells	cell	NOUN
fnp-3528	845	41	.	.	PUNCT
fnp-3528	846	1	neuroreport	neuroreport	NOUN
fnp-3528	846	2	2006	2006	NUM
fnp-3528	846	3	,	,	PUNCT
fnp-3528	846	4	17	17	NUM
fnp-3528	846	5	,	,	PUNCT
fnp-3528	846	6	891	891	NUM
fnp-3528	846	7	-	-	SYM
fnp-3528	846	8	6	6	NUM
fnp-3528	846	9	.	.	PUNCT
fnp-3528	847	1	whiley	whiley	PROPN
fnp-3528	847	2	,	,	PUNCT
fnp-3528	847	3	l.	l.	PROPN
fnp-3528	847	4	;	;	PUNCT
fnp-3528	847	5	sen	sen	PROPN
fnp-3528	847	6	,	,	PUNCT
fnp-3528	847	7	a.	a.	PROPN
fnp-3528	847	8	;	;	PUNCT
fnp-3528	847	9	heaton	heaton	PROPN
fnp-3528	847	10	,	,	PUNCT
fnp-3528	847	11	j.	j.	PROPN
fnp-3528	847	12	;	;	PUNCT
fnp-3528	847	13	proitsi	proitsi	PROPN
fnp-3528	847	14	,	,	PUNCT
fnp-3528	847	15	p.	p.	NOUN
fnp-3528	847	16	;	;	PUNCT
fnp-3528	847	17	garcía	garcía	ADJ
fnp-3528	847	18	-	-	PUNCT
fnp-3528	847	19	gómez	gómez	NOUN
fnp-3528	847	20	,	,	PUNCT
fnp-3528	847	21	d.	d.	PROPN
fnp-3528	847	22	;	;	PUNCT
fnp-3528	847	23	leung	leung	PROPN
fnp-3528	847	24	,	,	PUNCT
fnp-3528	847	25	r.	r.	PROPN
fnp-3528	847	26	;	;	PUNCT
fnp-3528	847	27	smith	smith	PROPN
fnp-3528	847	28	,	,	PUNCT
fnp-3528	847	29	n.	n.	PROPN
fnp-3528	847	30	;	;	PUNCT
fnp-3528	847	31	thambisetty	thambisetty	PROPN
fnp-3528	847	32	,	,	PUNCT
fnp-3528	847	33	m.	m.	NOUN
fnp-3528	847	34	;	;	PUNCT
fnp-3528	847	35	kloszewska	kloszewska	PROPN
fnp-3528	847	36	,	,	PUNCT
fnp-3528	847	37	i.	i.	PROPN
fnp-3528	847	38	;	;	PUNCT
fnp-3528	847	39	mecocci	mecocci	PROPN
fnp-3528	847	40	,	,	PUNCT
fnp-3528	847	41	p.	p.	NOUN
fnp-3528	847	42	;	;	PUNCT
fnp-3528	847	43	soininen	soininen	PROPN
fnp-3528	847	44	,	,	PUNCT
fnp-3528	847	45	h.	h.	PROPN
fnp-3528	847	46	;	;	PUNCT
fnp-3528	847	47	tsolaki	tsolaki	NOUN
fnp-3528	847	48	,	,	PUNCT
fnp-3528	847	49	m.	m.	NOUN
fnp-3528	847	50	;	;	PUNCT
fnp-3528	847	51	vellas	vellas	PROPN
fnp-3528	847	52	,	,	PUNCT
fnp-3528	847	53	b.	b.	PROPN
fnp-3528	847	54	;	;	PUNCT
fnp-3528	847	55	lovestone	lovestone	NOUN
fnp-3528	847	56	,	,	PUNCT
fnp-3528	847	57	s.	s.	PROPN
fnp-3528	847	58	;	;	PUNCT
fnp-3528	847	59	legido	legido	PROPN
fnp-3528	847	60	-	-	PUNCT
fnp-3528	847	61	quigley	quigley	PROPN
fnp-3528	847	62	,	,	PUNCT
fnp-3528	847	63	c.	c.	NOUN
fnp-3528	847	64	evidence	evidence	NOUN
fnp-3528	847	65	of	of	ADP
fnp-3528	847	66	altered	altered	ADJ
fnp-3528	847	67	phosphatidylcholine	phosphatidylcholine	NOUN
fnp-3528	847	68	metabolism	metabolism	NOUN
fnp-3528	847	69	in	in	ADP
fnp-3528	847	70	alzheimer	alzheimer	PROPN
fnp-3528	847	71	's	's	PART
fnp-3528	847	72	disease	disease	NOUN
fnp-3528	847	73	.	.	PUNCT
fnp-3528	848	1	neurobiol	neurobiol	PROPN
fnp-3528	848	2	aging	age	VERB
fnp-3528	848	3	2014	2014	NUM
fnp-3528	848	4	,	,	PUNCT
fnp-3528	848	5	35	35	NUM
fnp-3528	848	6	,	,	PUNCT
fnp-3528	848	7	271	271	NUM
fnp-3528	848	8	-	-	SYM
fnp-3528	848	9	8	8	NUM
fnp-3528	848	10	.	.	PUNCT
fnp-3528	849	1	allikmets	allikmet	NOUN
fnp-3528	849	2	,	,	PUNCT
fnp-3528	849	3	r.	r.	PROPN
fnp-3528	849	4	;	;	PUNCT
fnp-3528	849	5	singh	singh	PROPN
fnp-3528	849	6	,	,	PUNCT
fnp-3528	849	7	n.	n.	NOUN
fnp-3528	849	8	;	;	PUNCT
fnp-3528	849	9	sun	sun	PROPN
fnp-3528	849	10	,	,	PUNCT
fnp-3528	849	11	h.	h.	PROPN
fnp-3528	849	12	;	;	PUNCT
fnp-3528	849	13	shroyer	shroyer	NOUN
fnp-3528	849	14	,	,	PUNCT
fnp-3528	849	15	n.	n.	PROPN
fnp-3528	849	16	f.	f.	PROPN
fnp-3528	849	17	;	;	PUNCT
fnp-3528	849	18	hutchinson	hutchinson	PROPN
fnp-3528	849	19	,	,	PUNCT
fnp-3528	849	20	a.	a.	PROPN
fnp-3528	849	21	;	;	PUNCT
fnp-3528	849	22	chidambaram	chidambaram	PROPN
fnp-3528	849	23	,	,	PUNCT
fnp-3528	849	24	a.	a.	NOUN
fnp-3528	849	25	;	;	PUNCT
fnp-3528	849	26	gerrard	gerrard	PROPN
fnp-3528	849	27	,	,	PUNCT
fnp-3528	849	28	b.	b.	PROPN
fnp-3528	849	29	;	;	PUNCT
fnp-3528	849	30	baird	baird	PROPN
fnp-3528	849	31	,	,	PUNCT
fnp-3528	849	32	l.	l.	PROPN
fnp-3528	849	33	;	;	PUNCT
fnp-3528	849	34	stauffer	stauffer	PROPN
fnp-3528	849	35	,	,	PUNCT
fnp-3528	849	36	d.	d.	PROPN
fnp-3528	849	37	;	;	PUNCT
fnp-3528	849	38	peiffer	peiffer	NOUN
fnp-3528	849	39	,	,	PUNCT
fnp-3528	849	40	a.	a.	NOUN
fnp-3528	849	41	;	;	PUNCT
fnp-3528	849	42	rattner	rattner	NOUN
fnp-3528	849	43	,	,	PUNCT
fnp-3528	849	44	a.	a.	NOUN
fnp-3528	849	45	;	;	PUNCT
fnp-3528	849	46	smallwood	smallwood	PROPN
fnp-3528	849	47	,	,	PUNCT
fnp-3528	849	48	p.	p.	PROPN
fnp-3528	849	49	;	;	PUNCT
fnp-3528	849	50	li	li	PROPN
fnp-3528	849	51	,	,	PUNCT
fnp-3528	849	52	y.	y.	PROPN
fnp-3528	849	53	;	;	PUNCT
fnp-3528	849	54	anderson	anderson	PROPN
fnp-3528	849	55	,	,	PUNCT
fnp-3528	849	56	k.	k.	PROPN
fnp-3528	849	57	l.	l.	PROPN
fnp-3528	849	58	;	;	PUNCT
fnp-3528	849	59	lewis	lewis	PROPN
fnp-3528	849	60	,	,	PUNCT
fnp-3528	849	61	r.	r.	PROPN
fnp-3528	849	62	a.	a.	PROPN
fnp-3528	849	63	;	;	PUNCT
fnp-3528	849	64	nathans	nathans	PROPN
fnp-3528	849	65	,	,	PUNCT
fnp-3528	849	66	j.	j.	PROPN
fnp-3528	849	67	;	;	PUNCT
fnp-3528	849	68	leppert	leppert	ADJ
fnp-3528	849	69	,	,	PUNCT
fnp-3528	849	70	m.	m.	NOUN
fnp-3528	849	71	;	;	PUNCT
fnp-3528	849	72	dean	dean	PROPN
fnp-3528	849	73	,	,	PUNCT
fnp-3528	849	74	m.	m.	NOUN
fnp-3528	849	75	;	;	PUNCT
fnp-3528	849	76	lupski	lupski	PROPN
fnp-3528	849	77	,	,	PUNCT
fnp-3528	849	78	j.	j.	PROPN
fnp-3528	849	79	r.	r.	PROPN
fnp-3528	849	80	a	a	DET
fnp-3528	849	81	photoreceptor	photoreceptor	NOUN
fnp-3528	849	82	cell	cell	NOUN
fnp-3528	849	83	-	-	PUNCT
fnp-3528	849	84	specific	specific	ADJ
fnp-3528	849	85	atp	atp	NOUN
fnp-3528	849	86	-	-	PUNCT
fnp-3528	849	87	binding	bind	VERB
fnp-3528	849	88	transporter	transporter	NOUN
fnp-3528	849	89	gene	gene	NOUN
fnp-3528	849	90	(	(	PUNCT
fnp-3528	849	91	abcr	abcr	NOUN
fnp-3528	849	92	)	)	PUNCT
fnp-3528	849	93	is	be	AUX
fnp-3528	849	94	mutated	mutate	VERB
fnp-3528	849	95	in	in	ADP
fnp-3528	849	96	recessive	recessive	ADJ
fnp-3528	849	97	stargardt	stargardt	ADJ
fnp-3528	849	98	macular	macular	ADJ
fnp-3528	849	99	dystrophy	dystrophy	NOUN
fnp-3528	849	100	.	.	PUNCT
fnp-3528	850	1	nat	nat	PROPN
fnp-3528	850	2	genet	genet	PROPN
fnp-3528	850	3	1997	1997	NUM
fnp-3528	850	4	,	,	PUNCT
fnp-3528	850	5	15	15	NUM
fnp-3528	850	6	,	,	PUNCT
fnp-3528	850	7	236	236	NUM
fnp-3528	850	8	-	-	SYM
fnp-3528	850	9	46	46	NUM
fnp-3528	850	10	.	.	PUNCT
fnp-3528	851	1	kaway	kaway	PROPN
fnp-3528	851	2	,	,	PUNCT
fnp-3528	851	3	c.	c.	PROPN
fnp-3528	851	4	s.	s.	PROPN
fnp-3528	851	5	;	;	PUNCT
fnp-3528	851	6	adams	adams	PROPN
fnp-3528	851	7	,	,	PUNCT
fnp-3528	851	8	m.	m.	PROPN
fnp-3528	851	9	k.	k.	PROPN
fnp-3528	851	10	m.	m.	PROPN
fnp-3528	851	11	;	;	PUNCT
fnp-3528	851	12	jenkins	jenkins	PROPN
fnp-3528	851	13	,	,	PUNCT
fnp-3528	851	14	k.	k.	PROPN
fnp-3528	851	15	s.	s.	PROPN
fnp-3528	851	16	;	;	PUNCT
fnp-3528	851	17	layton	layton	PROPN
fnp-3528	851	18	,	,	PUNCT
fnp-3528	851	19	c.	c.	PROPN
fnp-3528	851	20	j.	j.	PROPN
fnp-3528	852	1	a	a	DET
fnp-3528	852	2	novel	novel	ADJ
fnp-3528	852	3	abca4	abca4	NOUN
fnp-3528	852	4	mutation	mutation	NOUN
fnp-3528	852	5	associated	associate	VERB
fnp-3528	852	6	with	with	ADP
fnp-3528	852	7	a	a	DET
fnp-3528	852	8	late	late	ADJ
fnp-3528	852	9	-	-	PUNCT
fnp-3528	852	10	onset	onset	NOUN
fnp-3528	852	11	stargardt	stargardt	ADJ
fnp-3528	852	12	disease	disease	NOUN
fnp-3528	852	13	phenotype	phenotype	NOUN
fnp-3528	852	14	:	:	PUNCT
fnp-3528	852	15	a	a	DET
fnp-3528	852	16	hypomorphic	hypomorphic	ADJ
fnp-3528	852	17	allele	allele	NOUN
fnp-3528	852	18	?	?	PUNCT
fnp-3528	853	1	case	case	NOUN
fnp-3528	853	2	rep	rep	PROPN
fnp-3528	853	3	ophthalmol	ophthalmol	PROPN
fnp-3528	853	4	2017	2017	NUM
fnp-3528	853	5	,	,	PUNCT
fnp-3528	853	6	8	8	NUM
fnp-3528	853	7	,	,	PUNCT
fnp-3528	853	8	180	180	NUM
fnp-3528	853	9	-	-	SYM
fnp-3528	853	10	4	4	NUM
fnp-3528	853	11	.	.	PUNCT
fnp-3528	853	12	muller	muller	NOUN
fnp-3528	853	13	,	,	PUNCT
fnp-3528	853	14	p.	p.	PROPN
fnp-3528	853	15	l.	l.	PROPN
fnp-3528	853	16	;	;	PUNCT
fnp-3528	853	17	treis	treis	PROPN
fnp-3528	853	18	,	,	PUNCT
fnp-3528	853	19	t.	t.	PROPN
fnp-3528	853	20	;	;	PUNCT
fnp-3528	853	21	odainic	odainic	ADJ
fnp-3528	853	22	,	,	PUNCT
fnp-3528	853	23	a.	a.	NOUN
fnp-3528	853	24	;	;	PUNCT
fnp-3528	853	25	pfau	pfau	NOUN
fnp-3528	853	26	,	,	PUNCT
fnp-3528	853	27	m.	m.	NOUN
fnp-3528	853	28	;	;	PUNCT
fnp-3528	853	29	herrmann	herrmann	PROPN
fnp-3528	853	30	,	,	PUNCT
fnp-3528	853	31	p.	p.	PROPN
fnp-3528	853	32	;	;	PUNCT
fnp-3528	853	33	tufail	tufail	NOUN
fnp-3528	853	34	,	,	PUNCT
fnp-3528	853	35	a.	a.	NOUN
fnp-3528	853	36	;	;	PUNCT
fnp-3528	853	37	holz	holz	PROPN
fnp-3528	853	38	,	,	PUNCT
fnp-3528	853	39	f.	f.	PROPN
fnp-3528	853	40	g.	g.	PROPN
fnp-3528	853	41	prediction	prediction	NOUN
fnp-3528	853	42	of	of	ADP
fnp-3528	853	43	function	function	NOUN
fnp-3528	853	44	in	in	ADP
fnp-3528	853	45	abca4	abca4	ADJ
fnp-3528	853	46	-	-	PUNCT
fnp-3528	853	47	related	relate	VERB
fnp-3528	853	48	retinopathy	retinopathy	NOUN
fnp-3528	853	49	using	use	VERB
fnp-3528	853	50	ensemble	ensemble	ADJ
fnp-3528	853	51	machine	machine	NOUN
fnp-3528	853	52	learning	learning	NOUN
fnp-3528	853	53	.	.	PUNCT
fnp-3528	854	1	j	j	PROPN
fnp-3528	854	2	clin	clin	PROPN
fnp-3528	854	3	med	med	PROPN
fnp-3528	854	4	2020	2020	NUM
fnp-3528	854	5	,	,	PUNCT
fnp-3528	854	6	9	9	NUM
fnp-3528	854	7	.	.	NOUN
fnp-3528	854	8	ohtsuki	ohtsuki	PROPN
fnp-3528	854	9	,	,	PUNCT
fnp-3528	854	10	s.	s.	PROPN
fnp-3528	854	11	;	;	PUNCT
fnp-3528	854	12	watanabe	watanabe	PROPN
fnp-3528	854	13	,	,	PUNCT
fnp-3528	854	14	y.	y.	PROPN
fnp-3528	854	15	;	;	PUNCT
fnp-3528	854	16	hori	hori	PROPN
fnp-3528	854	17	,	,	PUNCT
fnp-3528	854	18	s.	s.	PROPN
fnp-3528	854	19	;	;	PUNCT
fnp-3528	854	20	suzuki	suzuki	PROPN
fnp-3528	854	21	,	,	PUNCT
fnp-3528	854	22	h.	h.	PROPN
fnp-3528	854	23	;	;	PUNCT
fnp-3528	854	24	bhongsatiern	bhongsatiern	PROPN
fnp-3528	854	25	,	,	PUNCT
fnp-3528	854	26	j.	j.	PROPN
fnp-3528	854	27	;	;	PUNCT
fnp-3528	854	28	fujiyoshi	fujiyoshi	NOUN
fnp-3528	854	29	,	,	PUNCT
fnp-3528	854	30	m.	m.	NOUN
fnp-3528	854	31	;	;	PUNCT
fnp-3528	854	32	kamoi	kamoi	PROPN
fnp-3528	854	33	,	,	PUNCT
fnp-3528	854	34	m.	m.	NOUN
fnp-3528	854	35	;	;	PUNCT
fnp-3528	854	36	kamiya	kamiya	PROPN
fnp-3528	854	37	,	,	PUNCT
fnp-3528	854	38	n.	n.	NOUN
fnp-3528	854	39	;	;	PUNCT
fnp-3528	854	40	takanaga	takanaga	NOUN
fnp-3528	854	41	,	,	PUNCT
fnp-3528	854	42	h.	h.	PROPN
fnp-3528	854	43	;	;	PUNCT
fnp-3528	854	44	terasaki	terasaki	PROPN
fnp-3528	854	45	,	,	PUNCT
fnp-3528	854	46	t.	t.	PROPN
fnp-3528	854	47	mrna	mrna	PROPN
fnp-3528	854	48	expression	expression	NOUN
fnp-3528	854	49	of	of	ADP
fnp-3528	854	50	the	the	DET
fnp-3528	854	51	atp	atp	NOUN
fnp-3528	854	52	-	-	PUNCT
fnp-3528	854	53	binding	bind	VERB
fnp-3528	854	54	cassette	cassette	NOUN
fnp-3528	854	55	transporter	transporter	NOUN
fnp-3528	854	56	subfamily	subfamily	ADV
fnp-3528	854	57	a	a	DET
fnp-3528	854	58	(	(	PUNCT
fnp-3528	854	59	abca	abca	NOUN
fnp-3528	854	60	)	)	PUNCT
fnp-3528	854	61	in	in	ADP
fnp-3528	854	62	rat	rat	NOUN
fnp-3528	854	63	and	and	CCONJ
fnp-3528	854	64	human	human	ADJ
fnp-3528	854	65	brain	brain	NOUN
fnp-3528	854	66	capillary	capillary	ADJ
fnp-3528	854	67	endothelial	endothelial	ADJ
fnp-3528	854	68	cells	cell	NOUN
fnp-3528	854	69	.	.	PUNCT
fnp-3528	855	1	biol	biol	PROPN
fnp-3528	855	2	pharm	pharm	PROPN
fnp-3528	855	3	bull	bull	PROPN
fnp-3528	855	4	2004	2004	NUM
fnp-3528	855	5	,	,	PUNCT
fnp-3528	855	6	27	27	NUM
fnp-3528	855	7	,	,	PUNCT
fnp-3528	855	8	1437	1437	NUM
fnp-3528	855	9	-	-	SYM
fnp-3528	855	10	40	40	NUM
fnp-3528	855	11	.	.	PUNCT
fnp-3528	856	1	petry	petry	PROPN
fnp-3528	856	2	,	,	PUNCT
fnp-3528	856	3	f.	f.	PROPN
fnp-3528	856	4	;	;	PUNCT
fnp-3528	856	5	kotthaus	kotthaus	PROPN
fnp-3528	856	6	,	,	PUNCT
fnp-3528	856	7	a.	a.	PROPN
fnp-3528	856	8	;	;	PUNCT
fnp-3528	856	9	hirsch	hirsch	PROPN
fnp-3528	856	10	-	-	PUNCT
fnp-3528	856	11	ernst	ernst	PROPN
fnp-3528	856	12	,	,	PUNCT
fnp-3528	856	13	k.	k.	PROPN
fnp-3528	856	14	i.	i.	PROPN
fnp-3528	856	15	cloning	cloning	PROPN
fnp-3528	856	16	of	of	ADP
fnp-3528	856	17	human	human	ADJ
fnp-3528	856	18	and	and	CCONJ
fnp-3528	856	19	rat	rat	NOUN
fnp-3528	856	20	abca5	abca5	NOUN
fnp-3528	856	21	/	/	SYM
fnp-3528	856	22	abca5	abca5	NOUN
fnp-3528	856	23	and	and	CCONJ
fnp-3528	856	24	detection	detection	NOUN
fnp-3528	856	25	of	of	ADP
fnp-3528	856	26	a	a	DET
fnp-3528	856	27	human	human	ADJ
fnp-3528	856	28	splice	splice	NOUN
fnp-3528	856	29	variant	variant	NOUN
fnp-3528	856	30	.	.	PUNCT
fnp-3528	857	1	biochem	biochem	PROPN
fnp-3528	857	2	biophys	biophys	PROPN
fnp-3528	857	3	res	res	PROPN
fnp-3528	857	4	commun	commun	PROPN
fnp-3528	857	5	2003	2003	NUM
fnp-3528	857	6	,	,	PUNCT
fnp-3528	857	7	300	300	NUM
fnp-3528	857	8	,	,	PUNCT
fnp-3528	857	9	343	343	NUM
fnp-3528	857	10	-	-	SYM
fnp-3528	857	11	50	50	NUM
fnp-3528	857	12	.	.	PUNCT
fnp-3528	858	1	fu	fu	PROPN
fnp-3528	858	2	,	,	PUNCT
fnp-3528	858	3	y.	y.	PROPN
fnp-3528	858	4	;	;	PUNCT
fnp-3528	858	5	hsiao	hsiao	PROPN
fnp-3528	858	6	,	,	PUNCT
fnp-3528	858	7	j.	j.	PROPN
fnp-3528	858	8	h.	h.	PROPN
fnp-3528	858	9	;	;	PUNCT
fnp-3528	858	10	paxinos	paxino	NOUN
fnp-3528	858	11	,	,	PUNCT
fnp-3528	858	12	g.	g.	PROPN
fnp-3528	858	13	;	;	PUNCT
fnp-3528	858	14	halliday	halliday	PROPN
fnp-3528	858	15	,	,	PUNCT
fnp-3528	858	16	g.	g.	PROPN
fnp-3528	858	17	m.	m.	PROPN
fnp-3528	858	18	;	;	PUNCT
fnp-3528	858	19	kim	kim	PROPN
fnp-3528	858	20	,	,	PUNCT
fnp-3528	858	21	w.	w.	PROPN
fnp-3528	858	22	s.	s.	PROPN
fnp-3528	858	23	abca5	abca5	PROPN
fnp-3528	858	24	regulates	regulate	VERB
fnp-3528	858	25	amyloid	amyloid	NOUN
fnp-3528	858	26	-	-	PUNCT
fnp-3528	858	27	beta	beta	NOUN
fnp-3528	858	28	peptide	peptide	NOUN
fnp-3528	858	29	production	production	NOUN
fnp-3528	858	30	and	and	CCONJ
fnp-3528	858	31	is	be	AUX
fnp-3528	858	32	associated	associate	VERB
fnp-3528	858	33	with	with	ADP
fnp-3528	858	34	alzheimer	alzheimer	PROPN
fnp-3528	858	35	's	's	PART
fnp-3528	858	36	disease	disease	NOUN
fnp-3528	858	37	neuropathology	neuropathology	NOUN
fnp-3528	858	38	.	.	PUNCT
fnp-3528	859	1	j	j	PROPN
fnp-3528	859	2	alzheimers	alzheimers	PROPN
fnp-3528	859	3	dis	dis	PROPN
fnp-3528	859	4	2015	2015	NUM
fnp-3528	859	5	,	,	PUNCT
fnp-3528	859	6	43	43	NUM
fnp-3528	859	7	,	,	PUNCT
fnp-3528	859	8	857	857	NUM
fnp-3528	859	9	-	-	SYM
fnp-3528	859	10	69	69	NUM
fnp-3528	859	11	.	.	PUNCT
fnp-3528	860	1	kaminski	kaminski	PROPN
fnp-3528	860	2	,	,	PUNCT
fnp-3528	860	3	w.	w.	PROPN
fnp-3528	860	4	e.	e.	PROPN
fnp-3528	860	5	;	;	PUNCT
fnp-3528	860	6	wenzel	wenzel	PROPN
fnp-3528	860	7	,	,	PUNCT
fnp-3528	860	8	j.	j.	PROPN
fnp-3528	860	9	j.	j.	PROPN
fnp-3528	860	10	;	;	PUNCT
fnp-3528	860	11	piehler	piehler	PROPN
fnp-3528	860	12	,	,	PUNCT
fnp-3528	860	13	a.	a.	NOUN
fnp-3528	860	14	;	;	PUNCT
fnp-3528	860	15	langmann	langmann	PROPN
fnp-3528	860	16	,	,	PUNCT
fnp-3528	860	17	t.	t.	PROPN
fnp-3528	860	18	;	;	PUNCT
fnp-3528	860	19	schmitz	schmitz	PROPN
fnp-3528	860	20	,	,	PUNCT
fnp-3528	860	21	g.	g.	PROPN
fnp-3528	860	22	abca6	abca6	PROPN
fnp-3528	860	23	,	,	PUNCT
fnp-3528	860	24	a	a	DET
fnp-3528	860	25	novel	novel	NOUN
fnp-3528	860	26	a	a	DET
fnp-3528	860	27	subclass	subclass	NOUN
fnp-3528	860	28	abc	abc	PROPN
fnp-3528	860	29	transporter	transporter	NOUN
fnp-3528	860	30	.	.	PUNCT
fnp-3528	861	1	biochem	biochem	PROPN
fnp-3528	861	2	biophys	biophys	PROPN
fnp-3528	861	3	res	res	PROPN
fnp-3528	861	4	commun	commun	PROPN
fnp-3528	861	5	2001	2001	NUM
fnp-3528	861	6	,	,	PUNCT
fnp-3528	861	7	285	285	NUM
fnp-3528	861	8	,	,	PUNCT
fnp-3528	861	9	1295	1295	NUM
fnp-3528	861	10	-	-	SYM
fnp-3528	861	11	301	301	NUM
fnp-3528	861	12	.	.	PUNCT
fnp-3528	862	1	van	van	PROPN
fnp-3528	862	2	leeuwen	leeuwen	PROPN
fnp-3528	862	3	,	,	PUNCT
fnp-3528	862	4	e.	e.	PROPN
fnp-3528	862	5	m.	m.	PROPN
fnp-3528	862	6	;	;	PUNCT
fnp-3528	862	7	karssen	karssen	PROPN
fnp-3528	862	8	,	,	PUNCT
fnp-3528	862	9	l.	l.	PROPN
fnp-3528	862	10	c.	c.	PROPN
fnp-3528	862	11	;	;	PUNCT
fnp-3528	862	12	deelen	deelen	PROPN
fnp-3528	862	13	,	,	PUNCT
fnp-3528	862	14	j.	j.	PROPN
fnp-3528	862	15	;	;	PUNCT
fnp-3528	862	16	isaacs	isaacs	PROPN
fnp-3528	862	17	,	,	PUNCT
fnp-3528	862	18	a.	a.	PROPN
fnp-3528	862	19	;	;	PUNCT
fnp-3528	862	20	medina	medina	PROPN
fnp-3528	862	21	-	-	PUNCT
fnp-3528	862	22	gomez	gomez	PROPN
fnp-3528	862	23	,	,	PUNCT
fnp-3528	862	24	c.	c.	PROPN
fnp-3528	862	25	;	;	PUNCT
fnp-3528	862	26	mbarek	mbarek	PROPN
fnp-3528	862	27	,	,	PUNCT
fnp-3528	862	28	h.	h.	PROPN
fnp-3528	862	29	;	;	PUNCT
fnp-3528	862	30	kanterakis	kanteraki	NOUN
fnp-3528	862	31	,	,	PUNCT
fnp-3528	862	32	a.	a.	NOUN
fnp-3528	862	33	;	;	PUNCT
fnp-3528	862	34	trompet	trompet	PROPN
fnp-3528	862	35	,	,	PUNCT
fnp-3528	862	36	s.	s.	PROPN
fnp-3528	862	37	;	;	PUNCT
fnp-3528	862	38	postmus	postmus	PROPN
fnp-3528	862	39	,	,	PUNCT
fnp-3528	862	40	i.	i.	NOUN
fnp-3528	862	41	;	;	PUNCT
fnp-3528	862	42	verweij	verweij	PROPN
fnp-3528	862	43	,	,	PUNCT
fnp-3528	862	44	n.	n.	PROPN
fnp-3528	862	45	;	;	PUNCT
fnp-3528	862	46	van	van	PROPN
fnp-3528	862	47	enckevort	enckevort	PROPN
fnp-3528	862	48	,	,	PUNCT
fnp-3528	862	49	d.	d.	PROPN
fnp-3528	862	50	j.	j.	PROPN
fnp-3528	862	51	;	;	PUNCT
fnp-3528	862	52	huffman	huffman	PROPN
fnp-3528	862	53	,	,	PUNCT
fnp-3528	862	54	j.	j.	PROPN
fnp-3528	862	55	e.	e.	PROPN
fnp-3528	862	56	;	;	PUNCT
fnp-3528	862	57	white	white	PROPN
fnp-3528	862	58	,	,	PUNCT
fnp-3528	862	59	c.	c.	PROPN
fnp-3528	862	60	c.	c.	PROPN
fnp-3528	862	61	;	;	PUNCT
fnp-3528	862	62	feitosa	feitosa	NOUN
fnp-3528	862	63	,	,	PUNCT
fnp-3528	862	64	m.	m.	PROPN
fnp-3528	862	65	f.	f.	PROPN
fnp-3528	862	66	;	;	PUNCT
fnp-3528	862	67	bartz	bartz	NOUN
fnp-3528	862	68	,	,	PUNCT
fnp-3528	862	69	t.	t.	NOUN
fnp-3528	862	70	m.	m.	NOUN
fnp-3528	862	71	;	;	PUNCT
fnp-3528	862	72	manichaikul	manichaikul	NOUN
fnp-3528	862	73	,	,	PUNCT
fnp-3528	862	74	a.	a.	NOUN
fnp-3528	862	75	;	;	PUNCT
fnp-3528	862	76	joshi	joshi	PROPN
fnp-3528	862	77	,	,	PUNCT
fnp-3528	862	78	p.	p.	PROPN
fnp-3528	862	79	k.	k.	PROPN
fnp-3528	862	80	;	;	PUNCT
fnp-3528	862	81	peloso	peloso	NOUN
fnp-3528	862	82	,	,	PUNCT
fnp-3528	862	83	g.	g.	PROPN
fnp-3528	862	84	m.	m.	PROPN
fnp-3528	862	85	;	;	PUNCT
fnp-3528	862	86	deelen	deelen	NOUN
fnp-3528	862	87	,	,	PUNCT
fnp-3528	862	88	p.	p.	PROPN
fnp-3528	862	89	;	;	PUNCT
fnp-3528	862	90	van	van	PROPN
fnp-3528	862	91	dijk	dijk	PROPN
fnp-3528	862	92	,	,	PUNCT
fnp-3528	862	93	f.	f.	PROPN
fnp-3528	862	94	;	;	PUNCT
fnp-3528	862	95	willemsen	willemsen	NOUN
fnp-3528	862	96	,	,	PUNCT
fnp-3528	862	97	g.	g.	PROPN
fnp-3528	862	98	;	;	PUNCT
fnp-3528	862	99	de	de	X
fnp-3528	862	100	geus	geus	NOUN
fnp-3528	862	101	,	,	PUNCT
fnp-3528	862	102	e.	e.	PROPN
fnp-3528	862	103	j.	j.	PROPN
fnp-3528	862	104	;	;	PUNCT
fnp-3528	862	105	milaneschi	milaneschi	PROPN
fnp-3528	862	106	,	,	PUNCT
fnp-3528	862	107	y.	y.	PROPN
fnp-3528	862	108	;	;	PUNCT
fnp-3528	862	109	penninx	penninx	PROPN
fnp-3528	862	110	,	,	PUNCT
fnp-3528	862	111	b.	b.	PROPN
fnp-3528	862	112	w.	w.	PROPN
fnp-3528	862	113	;	;	PUNCT
fnp-3528	862	114	francioli	francioli	PROPN
fnp-3528	862	115	,	,	PUNCT
fnp-3528	862	116	l.	l.	PROPN
fnp-3528	862	117	c.	c.	PROPN
fnp-3528	862	118	;	;	PUNCT
fnp-3528	862	119	menelaou	menelaou	PROPN
fnp-3528	862	120	,	,	PUNCT
fnp-3528	862	121	a.	a.	NOUN
fnp-3528	862	122	;	;	PUNCT
fnp-3528	862	123	pulit	pulit	VERB
fnp-3528	862	124	,	,	PUNCT
fnp-3528	862	125	s.	s.	PROPN
fnp-3528	862	126	l.	l.	PROPN
fnp-3528	862	127	;	;	PUNCT
fnp-3528	862	128	rivadeneira	rivadeneira	PROPN
fnp-3528	862	129	,	,	PUNCT
fnp-3528	862	130	f.	f.	PROPN
fnp-3528	862	131	;	;	PUNCT
fnp-3528	862	132	hofman	hofman	PROPN
fnp-3528	862	133	,	,	PUNCT
fnp-3528	862	134	a.	a.	NOUN
fnp-3528	862	135	;	;	PUNCT
fnp-3528	862	136	oostra	oostra	PROPN
fnp-3528	862	137	,	,	PUNCT
fnp-3528	862	138	b.	b.	PROPN
fnp-3528	862	139	a.	a.	PROPN
fnp-3528	862	140	;	;	PUNCT
fnp-3528	862	141	franco	franco	PROPN
fnp-3528	862	142	,	,	PUNCT
fnp-3528	862	143	o.	o.	PROPN
fnp-3528	862	144	h.	h.	PROPN
fnp-3528	862	145	;	;	PUNCT
fnp-3528	862	146	mateo	mateo	NOUN
fnp-3528	862	147	leach	leach	NOUN
fnp-3528	862	148	,	,	PUNCT
fnp-3528	862	149	i.	i.	NOUN
fnp-3528	862	150	;	;	PUNCT
fnp-3528	862	151	beekman	beekman	NOUN
fnp-3528	862	152	,	,	PUNCT
fnp-3528	862	153	m.	m.	NOUN
fnp-3528	862	154	;	;	PUNCT
fnp-3528	862	155	de	de	X
fnp-3528	862	156	craen	craen	PROPN
fnp-3528	862	157	,	,	PUNCT
fnp-3528	862	158	a.	a.	PROPN
fnp-3528	862	159	j.	j.	PROPN
fnp-3528	862	160	;	;	PUNCT
fnp-3528	862	161	uh	uh	INTJ
fnp-3528	862	162	,	,	PUNCT
fnp-3528	862	163	h.	h.	PROPN
fnp-3528	862	164	w.	w.	PROPN
fnp-3528	862	165	;	;	PUNCT
fnp-3528	862	166	trochet	trochet	NOUN
fnp-3528	862	167	,	,	PUNCT
fnp-3528	862	168	h.	h.	PROPN
fnp-3528	862	169	;	;	PUNCT
fnp-3528	862	170	hocking	hocking	PROPN
fnp-3528	862	171	,	,	PUNCT
fnp-3528	862	172	l.	l.	PROPN
fnp-3528	862	173	j.	j.	PROPN
fnp-3528	862	174	;	;	PUNCT
fnp-3528	862	175	porteous	porteous	NOUN
fnp-3528	862	176	,	,	PUNCT
fnp-3528	862	177	d.	d.	PROPN
fnp-3528	862	178	j.	j.	PROPN
fnp-3528	862	179	;	;	PUNCT
fnp-3528	862	180	sattar	sattar	PROPN
fnp-3528	862	181	,	,	PUNCT
fnp-3528	862	182	n.	n.	NOUN
fnp-3528	862	183	;	;	PUNCT
fnp-3528	862	184	packard	packard	NOUN
fnp-3528	862	185	,	,	PUNCT
fnp-3528	862	186	c.	c.	PROPN
fnp-3528	862	187	j.	j.	PROPN
fnp-3528	862	188	;	;	PUNCT
fnp-3528	862	189	buckley	buckley	PROPN
fnp-3528	862	190	,	,	PUNCT
fnp-3528	862	191	b.	b.	PROPN
fnp-3528	862	192	m.	m.	PROPN
fnp-3528	862	193	;	;	PUNCT
fnp-3528	862	194	brody	brody	PROPN
fnp-3528	862	195	,	,	PUNCT
fnp-3528	862	196	j.	j.	PROPN
fnp-3528	862	197	a.	a.	PROPN
fnp-3528	862	198	;	;	PUNCT
fnp-3528	862	199	bis	bis	PROPN
fnp-3528	862	200	,	,	PUNCT
fnp-3528	862	201	j.	j.	PROPN
fnp-3528	862	202	c.	c.	PROPN
fnp-3528	862	203	;	;	PUNCT
fnp-3528	862	204	rotter	rotter	NOUN
fnp-3528	862	205	,	,	PUNCT
fnp-3528	862	206	j.	j.	PROPN
fnp-3528	862	207	i.	i.	PROPN
fnp-3528	862	208	;	;	PUNCT
fnp-3528	862	209	mychaleckyj	mychaleckyj	NOUN
fnp-3528	862	210	,	,	PUNCT
fnp-3528	862	211	j.	j.	PROPN
fnp-3528	862	212	c.	c.	PROPN
fnp-3528	862	213	;	;	PUNCT
fnp-3528	862	214	campbell	campbell	PROPN
fnp-3528	862	215	,	,	PUNCT
fnp-3528	862	216	h.	h.	PROPN
fnp-3528	862	217	;	;	PUNCT
fnp-3528	862	218	duan	duan	PROPN
fnp-3528	862	219	,	,	PUNCT
fnp-3528	862	220	q.	q.	PROPN
fnp-3528	862	221	;	;	PUNCT
fnp-3528	862	222	lange	lange	PROPN
fnp-3528	862	223	,	,	PUNCT
fnp-3528	862	224	l.	l.	PROPN
fnp-3528	862	225	a.	a.	PROPN
fnp-3528	862	226	;	;	PUNCT
fnp-3528	862	227	wilson	wilson	PROPN
fnp-3528	862	228	,	,	PUNCT
fnp-3528	862	229	j.	j.	PROPN
fnp-3528	862	230	f.	f.	PROPN
fnp-3528	862	231	;	;	PUNCT
fnp-3528	862	232	hayward	hayward	PROPN
fnp-3528	862	233	,	,	PUNCT
fnp-3528	862	234	c.	c.	PROPN
fnp-3528	862	235	;	;	PUNCT
fnp-3528	862	236	polasek	polasek	NOUN
fnp-3528	862	237	,	,	PUNCT
fnp-3528	862	238	o.	o.	PROPN
fnp-3528	862	239	;	;	PUNCT
fnp-3528	862	240	vitart	vitart	NOUN
fnp-3528	862	241	,	,	PUNCT
fnp-3528	862	242	v.	v.	PROPN
fnp-3528	862	243	;	;	PUNCT
fnp-3528	862	244	rudan	rudan	PROPN
fnp-3528	862	245	,	,	PUNCT
fnp-3528	862	246	i.	i.	PROPN
fnp-3528	862	247	;	;	PUNCT
fnp-3528	862	248	wright	wright	PROPN
fnp-3528	862	249	,	,	PUNCT
fnp-3528	862	250	a.	a.	PROPN
fnp-3528	862	251	f.	f.	PROPN
fnp-3528	862	252	;	;	PUNCT
fnp-3528	862	253	rich	rich	ADJ
fnp-3528	862	254	,	,	PUNCT
fnp-3528	862	255	s.	s.	PROPN
fnp-3528	862	256	s.	s.	PROPN
fnp-3528	862	257	;	;	PUNCT
fnp-3528	862	258	psaty	psaty	PROPN
fnp-3528	862	259	,	,	PUNCT
fnp-3528	862	260	b.	b.	PROPN
fnp-3528	862	261	m.	m.	PROPN
fnp-3528	862	262	;	;	PUNCT
fnp-3528	862	263	borecki	borecki	ADJ
fnp-3528	862	264	,	,	PUNCT
fnp-3528	862	265	i.	i.	PROPN
fnp-3528	862	266	b.	b.	PROPN
fnp-3528	862	267	;	;	PUNCT
fnp-3528	862	268	kearney	kearney	PROPN
fnp-3528	862	269	,	,	PUNCT
fnp-3528	862	270	p.	p.	PROPN
fnp-3528	862	271	m.	m.	NOUN
fnp-3528	862	272	;	;	PUNCT
fnp-3528	862	273	stott	stott	PROPN
fnp-3528	862	274	,	,	PUNCT
fnp-3528	862	275	d.	d.	PROPN
fnp-3528	862	276	j.	j.	PROPN
fnp-3528	862	277	;	;	PUNCT
fnp-3528	862	278	adrienne	adrienne	PROPN
fnp-3528	862	279	cupples	cupples	PROPN
fnp-3528	862	280	,	,	PUNCT
fnp-3528	862	281	l.	l.	PROPN
fnp-3528	862	282	;	;	PUNCT
fnp-3528	862	283	jukema	jukema	PROPN
fnp-3528	862	284	,	,	PUNCT
fnp-3528	862	285	j.	j.	PROPN
fnp-3528	862	286	w.	w.	PROPN
fnp-3528	862	287	;	;	PUNCT
fnp-3528	862	288	van	van	PROPN
fnp-3528	862	289	der	der	PROPN
fnp-3528	862	290	harst	harst	PROPN
fnp-3528	862	291	,	,	PUNCT
fnp-3528	862	292	p.	p.	NOUN
fnp-3528	862	293	;	;	PUNCT
fnp-3528	862	294	sijbrands	sijbrand	NOUN
fnp-3528	862	295	,	,	PUNCT
fnp-3528	862	296	e.	e.	PROPN
fnp-3528	862	297	j.	j.	PROPN
fnp-3528	862	298	;	;	PUNCT
fnp-3528	862	299	hottenga	hottenga	PROPN
fnp-3528	862	300	,	,	PUNCT
fnp-3528	862	301	j.	j.	PROPN
fnp-3528	862	302	j.	j.	PROPN
fnp-3528	862	303	;	;	PUNCT
fnp-3528	862	304	uitterlinden	uitterlinden	ADJ
fnp-3528	862	305	,	,	PUNCT
fnp-3528	862	306	a.	a.	NOUN
fnp-3528	862	307	g.	g.	PROPN
fnp-3528	862	308	;	;	PUNCT
fnp-3528	862	309	swertz	swertz	PROPN
fnp-3528	862	310	,	,	PUNCT
fnp-3528	862	311	m.	m.	NOUN
fnp-3528	862	312	a.	a.	PROPN
fnp-3528	862	313	;	;	PUNCT
fnp-3528	862	314	van	van	PROPN
fnp-3528	862	315	ommen	omman	NOUN
fnp-3528	862	316	,	,	PUNCT
fnp-3528	862	317	g.	g.	PROPN
fnp-3528	862	318	j.	j.	PROPN
fnp-3528	862	319	;	;	PUNCT
fnp-3528	862	320	de	de	PROPN
fnp-3528	862	321	bakker	bakker	PROPN
fnp-3528	862	322	,	,	PUNCT
fnp-3528	862	323	p.	p.	NOUN
fnp-3528	862	324	i.	i.	PROPN
fnp-3528	862	325	;	;	PUNCT
fnp-3528	862	326	eline	eline	PROPN
fnp-3528	862	327	slagboom	slagboom	PROPN
fnp-3528	862	328	,	,	PUNCT
fnp-3528	862	329	p.	p.	PROPN
fnp-3528	862	330	;	;	PUNCT
fnp-3528	862	331	boomsma	boomsma	PROPN
fnp-3528	862	332	,	,	PUNCT
fnp-3528	862	333	d.	d.	PROPN
fnp-3528	862	334	i.	i.	PROPN
fnp-3528	862	335	;	;	PUNCT
fnp-3528	862	336	wijmenga	wijmenga	PROPN
fnp-3528	862	337	,	,	PUNCT
fnp-3528	862	338	c.	c.	PROPN
fnp-3528	862	339	;	;	PUNCT
fnp-3528	862	340	van	van	PROPN
fnp-3528	862	341	duijn	duijn	PROPN
fnp-3528	862	342	,	,	PUNCT
fnp-3528	862	343	c.	c.	PROPN
fnp-3528	862	344	m.	m.	NOUN
fnp-3528	862	345	genome	genome	NOUN
fnp-3528	862	346	of	of	ADP
fnp-3528	862	347	the	the	DET
fnp-3528	862	348	netherlands	netherlands	PROPN
fnp-3528	862	349	population	population	NOUN
fnp-3528	862	350	-	-	PUNCT
fnp-3528	862	351	specific	specific	ADJ
fnp-3528	862	352	imputations	imputation	NOUN
fnp-3528	862	353	identify	identify	VERB
fnp-3528	862	354	an	an	DET
fnp-3528	862	355	abca6	abca6	NOUN
fnp-3528	862	356	variant	variant	NOUN
fnp-3528	862	357	associated	associate	VERB
fnp-3528	862	358	with	with	ADP
fnp-3528	862	359	cholesterol	cholesterol	NOUN
fnp-3528	862	360	levels	level	NOUN
fnp-3528	862	361	.	.	PUNCT
fnp-3528	863	1	nat	nat	PROPN
fnp-3528	863	2	commun	commun	PROPN
fnp-3528	863	3	2015	2015	NUM
fnp-3528	863	4	,	,	PUNCT
fnp-3528	863	5	6	6	NUM
fnp-3528	863	6	,	,	PUNCT
fnp-3528	863	7	6065	6065	NUM
fnp-3528	863	8	.	.	PUNCT
fnp-3528	864	1	dib	dib	PROPN
fnp-3528	864	2	,	,	PUNCT
fnp-3528	864	3	s.	s.	PROPN
fnp-3528	864	4	;	;	PUNCT
fnp-3528	864	5	pahnke	pahnke	PROPN
fnp-3528	864	6	,	,	PUNCT
fnp-3528	864	7	j.	j.	PROPN
fnp-3528	864	8	;	;	PUNCT
fnp-3528	864	9	gosselet	gosselet	NOUN
fnp-3528	864	10	,	,	PUNCT
fnp-3528	864	11	f.	f.	NOUN
fnp-3528	864	12	role	role	NOUN
fnp-3528	864	13	of	of	ADP
fnp-3528	864	14	abca7	abca7	PROPN
fnp-3528	864	15	in	in	ADP
fnp-3528	864	16	human	human	ADJ
fnp-3528	864	17	health	health	NOUN
fnp-3528	864	18	and	and	CCONJ
fnp-3528	864	19	in	in	ADP
fnp-3528	864	20	alzheimer	alzheimer	PROPN
fnp-3528	864	21	's	's	PART
fnp-3528	864	22	disease	disease	NOUN
fnp-3528	864	23	.	.	PUNCT
fnp-3528	865	1	int	int	PROPN
fnp-3528	865	2	j	j	PROPN
fnp-3528	865	3	mol	mol	ADP
fnp-3528	865	4	sci	sci	PROPN
fnp-3528	865	5	2021	2021	NUM
fnp-3528	865	6	,	,	PUNCT
fnp-3528	865	7	22	22	NUM
fnp-3528	865	8	,	,	PUNCT
fnp-3528	865	9	4603	4603	NUM
fnp-3528	865	10	.	.	PUNCT
fnp-3528	866	1	kaminski	kaminski	PROPN
fnp-3528	866	2	,	,	PUNCT
fnp-3528	866	3	w.	w.	PROPN
fnp-3528	866	4	e.	e.	PROPN
fnp-3528	866	5	;	;	PUNCT
fnp-3528	866	6	piehler	piehler	PROPN
fnp-3528	866	7	,	,	PUNCT
fnp-3528	866	8	a.	a.	NOUN
fnp-3528	866	9	;	;	PUNCT
fnp-3528	866	10	schmitz	schmitz	PROPN
fnp-3528	866	11	,	,	PUNCT
fnp-3528	866	12	g.	g.	PROPN
fnp-3528	866	13	genomic	genomic	PROPN
fnp-3528	866	14	organization	organization	NOUN
fnp-3528	866	15	of	of	ADP
fnp-3528	866	16	the	the	DET
fnp-3528	866	17	human	human	ADJ
fnp-3528	866	18	cholesterol	cholesterol	NOUN
fnp-3528	866	19	-	-	PUNCT
fnp-3528	866	20	responsive	responsive	ADJ
fnp-3528	866	21	abc	abc	PROPN
fnp-3528	866	22	transporter	transporter	NOUN
fnp-3528	866	23	abca7	abca7	NOUN
fnp-3528	866	24	:	:	PUNCT
fnp-3528	866	25	tandem	tandem	VERB
fnp-3528	866	26	linkage	linkage	NOUN
fnp-3528	866	27	with	with	ADP
fnp-3528	866	28	the	the	DET
fnp-3528	866	29	minor	minor	ADJ
fnp-3528	866	30	histocompatibility	histocompatibility	NOUN
fnp-3528	866	31	antigen	antigen	NOUN
fnp-3528	866	32	ha-1	ha-1	NUM
fnp-3528	866	33	gene	gene	NOUN
fnp-3528	866	34	.	.	PUNCT
fnp-3528	867	1	biochem	biochem	PROPN
fnp-3528	867	2	biophys	biophys	PROPN
fnp-3528	867	3	res	re	NOUN
fnp-3528	867	4	commun	commun	PROPN
fnp-3528	867	5	2000	2000	NUM
fnp-3528	867	6	,	,	PUNCT
fnp-3528	867	7	278	278	NUM
fnp-3528	867	8	,	,	PUNCT
fnp-3528	867	9	782	782	NUM
fnp-3528	867	10	-	-	SYM
fnp-3528	867	11	9	9	NUM
fnp-3528	867	12	.	.	PUNCT
fnp-3528	868	1	kaminski	kaminski	PROPN
fnp-3528	868	2	,	,	PUNCT
fnp-3528	868	3	w.	w.	PROPN
fnp-3528	868	4	e.	e.	PROPN
fnp-3528	868	5	;	;	PUNCT
fnp-3528	868	6	orso	orso	PROPN
fnp-3528	868	7	,	,	PUNCT
fnp-3528	868	8	e.	e.	PROPN
fnp-3528	868	9	;	;	PUNCT
fnp-3528	868	10	diederich	diederich	PROPN
fnp-3528	868	11	,	,	PUNCT
fnp-3528	868	12	w.	w.	PROPN
fnp-3528	868	13	;	;	PUNCT
fnp-3528	868	14	klucken	klucken	PROPN
fnp-3528	868	15	,	,	PUNCT
fnp-3528	868	16	j.	j.	PROPN
fnp-3528	868	17	;	;	PUNCT
fnp-3528	868	18	drobnik	drobnik	PROPN
fnp-3528	868	19	,	,	PUNCT
fnp-3528	868	20	w.	w.	PROPN
fnp-3528	868	21	;	;	PUNCT
fnp-3528	868	22	schmitz	schmitz	PROPN
fnp-3528	868	23	,	,	PUNCT
fnp-3528	868	24	g.	g.	PROPN
fnp-3528	868	25	identification	identification	NOUN
fnp-3528	868	26	of	of	ADP
fnp-3528	868	27	a	a	DET
fnp-3528	868	28	novel	novel	ADJ
fnp-3528	868	29	human	human	ADJ
fnp-3528	868	30	sterol	sterol	NOUN
fnp-3528	868	31	-	-	PUNCT
fnp-3528	868	32	sensitive	sensitive	ADJ
fnp-3528	868	33	atp	atp	NOUN
fnp-3528	868	34	-	-	PUNCT
fnp-3528	868	35	binding	bind	VERB
fnp-3528	868	36	cassette	cassette	NOUN
fnp-3528	868	37	transporter	transporter	NOUN
fnp-3528	868	38	(	(	PUNCT
fnp-3528	868	39	abca7	abca7	PROPN
fnp-3528	868	40	)	)	PUNCT
fnp-3528	868	41	.	.	PUNCT
fnp-3528	869	1	biochem	biochem	PROPN
fnp-3528	869	2	biophys	biophys	PROPN
fnp-3528	869	3	res	re	NOUN
fnp-3528	869	4	commun	commun	PROPN
fnp-3528	869	5	2000	2000	NUM
fnp-3528	869	6	,	,	PUNCT
fnp-3528	869	7	273	273	NUM
fnp-3528	869	8	,	,	PUNCT
fnp-3528	869	9	532	532	NUM
fnp-3528	869	10	-	-	SYM
fnp-3528	869	11	8	8	NUM
fnp-3528	869	12	.	.	PUNCT
fnp-3528	870	1	quazi	quazi	PROPN
fnp-3528	870	2	,	,	PUNCT
fnp-3528	870	3	f.	f.	PROPN
fnp-3528	870	4	;	;	PUNCT
fnp-3528	870	5	molday	molday	PROPN
fnp-3528	870	6	,	,	PUNCT
fnp-3528	870	7	r.	r.	PROPN
fnp-3528	870	8	s.	s.	PROPN
fnp-3528	870	9	differential	differential	PROPN
fnp-3528	870	10	phospholipid	phospholipid	NOUN
fnp-3528	870	11	substrates	substrate	NOUN
fnp-3528	870	12	and	and	CCONJ
fnp-3528	870	13	directional	directional	ADJ
fnp-3528	870	14	transport	transport	NOUN
fnp-3528	870	15	by	by	ADP
fnp-3528	870	16	atp	atp	NOUN
fnp-3528	870	17	-	-	PUNCT
fnp-3528	870	18	binding	bind	VERB
fnp-3528	870	19	cassette	cassette	NOUN
fnp-3528	870	20	proteins	protein	NOUN
fnp-3528	870	21	abca1	abca1	NOUN
fnp-3528	870	22	,	,	PUNCT
fnp-3528	870	23	abca7	abca7	NOUN
fnp-3528	870	24	,	,	PUNCT
fnp-3528	870	25	and	and	CCONJ
fnp-3528	870	26	abca4	abca4	ADJ
fnp-3528	870	27	and	and	CCONJ
fnp-3528	870	28	disease	disease	NOUN
fnp-3528	870	29	-	-	PUNCT
fnp-3528	870	30	causing	cause	VERB
fnp-3528	870	31	mutants	mutant	NOUN
fnp-3528	870	32	.	.	PUNCT
fnp-3528	871	1	j	j	PROPN
fnp-3528	871	2	biol	biol	PROPN
fnp-3528	871	3	chem	chem	NOUN
fnp-3528	871	4	2013	2013	NUM
fnp-3528	871	5	,	,	PUNCT
fnp-3528	871	6	288	288	NUM
fnp-3528	871	7	,	,	PUNCT
fnp-3528	871	8	34414	34414	NUM
fnp-3528	871	9	-	-	SYM
fnp-3528	871	10	26	26	NUM
fnp-3528	871	11	.	.	PUNCT
fnp-3528	872	1	hayashi	hayashi	PROPN
fnp-3528	872	2	,	,	PUNCT
fnp-3528	872	3	m.	m.	NOUN
fnp-3528	872	4	;	;	PUNCT
fnp-3528	872	5	abe	abe	PROPN
fnp-3528	872	6	-	-	PUNCT
fnp-3528	872	7	dohmae	dohmae	PROPN
fnp-3528	872	8	,	,	PUNCT
fnp-3528	872	9	s.	s.	PROPN
fnp-3528	872	10	;	;	PUNCT
fnp-3528	872	11	okazaki	okazaki	PROPN
fnp-3528	872	12	,	,	PUNCT
fnp-3528	872	13	m.	m.	NOUN
fnp-3528	872	14	;	;	PUNCT
fnp-3528	872	15	ueda	ueda	PROPN
fnp-3528	872	16	,	,	PUNCT
fnp-3528	872	17	k.	k.	PROPN
fnp-3528	872	18	;	;	PUNCT
fnp-3528	872	19	yokoyama	yokoyama	PROPN
fnp-3528	872	20	,	,	PUNCT
fnp-3528	872	21	s.	s.	PROPN
fnp-3528	872	22	heterogeneity	heterogeneity	PROPN
fnp-3528	872	23	of	of	ADP
fnp-3528	872	24	high	high	ADJ
fnp-3528	872	25	density	density	NOUN
fnp-3528	872	26	lipoprotein	lipoprotein	NOUN
fnp-3528	872	27	generated	generate	VERB
fnp-3528	872	28	by	by	ADP
fnp-3528	872	29	abca1	abca1	NOUN
fnp-3528	872	30	and	and	CCONJ
fnp-3528	872	31	abca7	abca7	PROPN
fnp-3528	872	32	.	.	PUNCT
fnp-3528	873	1	j	j	PROPN
fnp-3528	873	2	lipid	lipid	PROPN
fnp-3528	873	3	res	re	NOUN
fnp-3528	873	4	2005	2005	NUM
fnp-3528	873	5	,	,	PUNCT
fnp-3528	873	6	46	46	NUM
fnp-3528	873	7	,	,	PUNCT
fnp-3528	873	8	1703	1703	NUM
fnp-3528	873	9	-	-	SYM
fnp-3528	873	10	11	11	NUM
fnp-3528	873	11	.	.	PUNCT
fnp-3528	874	1	tanaka	tanaka	PROPN
fnp-3528	874	2	,	,	PUNCT
fnp-3528	874	3	n.	n.	PROPN
fnp-3528	874	4	;	;	PUNCT
fnp-3528	874	5	abe	abe	PROPN
fnp-3528	874	6	-	-	PUNCT
fnp-3528	874	7	dohmae	dohmae	PROPN
fnp-3528	874	8	,	,	PUNCT
fnp-3528	874	9	s.	s.	PROPN
fnp-3528	874	10	;	;	PUNCT
fnp-3528	874	11	iwamoto	iwamoto	ADJ
fnp-3528	874	12	,	,	PUNCT
fnp-3528	874	13	n.	n.	NOUN
fnp-3528	874	14	;	;	PUNCT
fnp-3528	874	15	yokoyama	yokoyama	PROPN
fnp-3528	874	16	,	,	PUNCT
fnp-3528	874	17	s.	s.	PROPN
fnp-3528	874	18	roles	role	NOUN
fnp-3528	874	19	of	of	ADP
fnp-3528	874	20	atp	atp	NOUN
fnp-3528	874	21	-	-	PUNCT
fnp-3528	874	22	binding	bind	VERB
fnp-3528	874	23	cassette	cassette	NOUN
fnp-3528	874	24	transporter	transporter	NOUN
fnp-3528	874	25	a7	a7	VERB
fnp-3528	874	26	in	in	ADP
fnp-3528	874	27	cholesterol	cholesterol	NOUN
fnp-3528	874	28	homeostasis	homeostasis	NOUN
fnp-3528	874	29	and	and	CCONJ
fnp-3528	874	30	host	host	NOUN
fnp-3528	874	31	defense	defense	NOUN
fnp-3528	874	32	system	system	NOUN
fnp-3528	874	33	.	.	PUNCT
fnp-3528	875	1	j	j	PROPN
fnp-3528	875	2	atheroscler	atheroscler	PROPN
fnp-3528	875	3	thromb	thromb	PROPN
fnp-3528	875	4	2011	2011	NUM
fnp-3528	875	5	,	,	PUNCT
fnp-3528	875	6	18	18	NUM
fnp-3528	875	7	,	,	PUNCT
fnp-3528	875	8	274	274	NUM
fnp-3528	875	9	-	-	SYM
fnp-3528	875	10	81	81	NUM
fnp-3528	875	11	.	.	PUNCT
fnp-3528	876	1	jehle	jehle	PROPN
fnp-3528	876	2	,	,	PUNCT
fnp-3528	876	3	a.	a.	PROPN
fnp-3528	876	4	w.	w.	PROPN
fnp-3528	876	5	;	;	PUNCT
fnp-3528	876	6	gardai	gardai	PROPN
fnp-3528	876	7	,	,	PUNCT
fnp-3528	876	8	s.	s.	PROPN
fnp-3528	876	9	j.	j.	PROPN
fnp-3528	876	10	;	;	PUNCT
fnp-3528	876	11	li	li	PROPN
fnp-3528	876	12	,	,	PUNCT
fnp-3528	876	13	s.	s.	PROPN
fnp-3528	876	14	;	;	PUNCT
fnp-3528	876	15	linsel	linsel	ADJ
fnp-3528	876	16	-	-	PUNCT
fnp-3528	876	17	nitschke	nitschke	NOUN
fnp-3528	876	18	,	,	PUNCT
fnp-3528	876	19	p.	p.	NOUN
fnp-3528	876	20	;	;	PUNCT
fnp-3528	876	21	morimoto	morimoto	NOUN
fnp-3528	876	22	,	,	PUNCT
fnp-3528	876	23	k.	k.	PROPN
fnp-3528	876	24	;	;	PUNCT
fnp-3528	876	25	janssen	janssen	PROPN
fnp-3528	876	26	,	,	PUNCT
fnp-3528	876	27	w.	w.	PROPN
fnp-3528	876	28	j.	j.	PROPN
fnp-3528	876	29	;	;	PUNCT
fnp-3528	876	30	vandivier	vandivier	PROPN
fnp-3528	876	31	,	,	PUNCT
fnp-3528	876	32	r.	r.	PROPN
fnp-3528	876	33	w.	w.	PROPN
fnp-3528	876	34	;	;	PUNCT
fnp-3528	876	35	wang	wang	PROPN
fnp-3528	876	36	,	,	PUNCT
fnp-3528	876	37	n.	n.	PROPN
fnp-3528	876	38	;	;	PUNCT
fnp-3528	876	39	greenberg	greenberg	PROPN
fnp-3528	876	40	,	,	PUNCT
fnp-3528	876	41	s.	s.	PROPN
fnp-3528	876	42	;	;	PUNCT
fnp-3528	876	43	dale	dale	PROPN
fnp-3528	876	44	,	,	PUNCT
fnp-3528	876	45	b.	b.	PROPN
fnp-3528	876	46	m.	m.	PROPN
fnp-3528	876	47	;	;	PUNCT
fnp-3528	876	48	qin	qin	PROPN
fnp-3528	876	49	,	,	PUNCT
fnp-3528	876	50	c.	c.	PROPN
fnp-3528	876	51	;	;	PUNCT
fnp-3528	876	52	henson	henson	PROPN
fnp-3528	876	53	,	,	PUNCT
fnp-3528	876	54	p.	p.	NOUN
fnp-3528	876	55	m.	m.	NOUN
fnp-3528	876	56	;	;	PUNCT
fnp-3528	876	57	tall	tall	ADJ
fnp-3528	876	58	,	,	PUNCT
fnp-3528	876	59	a.	a.	PROPN
fnp-3528	876	60	r.	r.	PROPN
fnp-3528	876	61	atp	atp	PROPN
fnp-3528	876	62	-	-	PUNCT
fnp-3528	876	63	binding	bind	VERB
fnp-3528	876	64	cassette	cassette	NOUN
fnp-3528	876	65	transporter	transporter	NOUN
fnp-3528	876	66	a7	a7	NOUN
fnp-3528	876	67	enhances	enhance	VERB
fnp-3528	876	68	phagocytosis	phagocytosis	NOUN
fnp-3528	876	69	of	of	ADP
fnp-3528	876	70	apoptotic	apoptotic	ADJ
fnp-3528	876	71	cells	cell	NOUN
fnp-3528	876	72	and	and	CCONJ
fnp-3528	876	73	associated	associate	VERB
fnp-3528	876	74	erk	erk	NOUN
fnp-3528	876	75	signaling	signal	VERB
fnp-3528	876	76	in	in	ADP
fnp-3528	876	77	macrophages	macrophage	NOUN
fnp-3528	876	78	.	.	PUNCT
fnp-3528	877	1	j	j	PROPN
fnp-3528	877	2	cell	cell	NOUN
fnp-3528	877	3	biol	biol	PROPN
fnp-3528	877	4	2006	2006	NUM
fnp-3528	877	5	,	,	PUNCT
fnp-3528	877	6	174	174	NUM
fnp-3528	877	7	,	,	PUNCT
fnp-3528	877	8	547	547	NUM
fnp-3528	877	9	-	-	SYM
fnp-3528	877	10	56	56	NUM
fnp-3528	877	11	.	.	PUNCT
fnp-3528	878	1	iwamoto	iwamoto	ADJ
fnp-3528	878	2	,	,	PUNCT
fnp-3528	878	3	n.	n.	NOUN
fnp-3528	878	4	;	;	PUNCT
fnp-3528	878	5	abe	abe	PROPN
fnp-3528	878	6	-	-	PUNCT
fnp-3528	878	7	dohmae	dohmae	PROPN
fnp-3528	878	8	,	,	PUNCT
fnp-3528	878	9	s.	s.	PROPN
fnp-3528	878	10	;	;	PUNCT
fnp-3528	878	11	sato	sato	PROPN
fnp-3528	878	12	,	,	PUNCT
fnp-3528	878	13	r.	r.	PROPN
fnp-3528	878	14	;	;	PUNCT
fnp-3528	878	15	yokoyama	yokoyama	PROPN
fnp-3528	878	16	,	,	PUNCT
fnp-3528	878	17	s.	s.	PROPN
fnp-3528	878	18	abca7	abca7	PROPN
fnp-3528	878	19	expression	expression	NOUN
fnp-3528	878	20	is	be	AUX
fnp-3528	878	21	regulated	regulate	VERB
fnp-3528	878	22	by	by	ADP
fnp-3528	878	23	cellular	cellular	ADJ
fnp-3528	878	24	cholesterol	cholesterol	NOUN
fnp-3528	878	25	through	through	ADP
fnp-3528	878	26	the	the	DET
fnp-3528	878	27	srebp2	srebp2	NOUN
fnp-3528	878	28	pathway	pathway	NOUN
fnp-3528	878	29	and	and	CCONJ
fnp-3528	878	30	associated	associate	VERB
fnp-3528	878	31	with	with	ADP
fnp-3528	878	32	phagocytosis	phagocytosis	NOUN
fnp-3528	878	33	.	.	PUNCT
fnp-3528	879	1	j	j	PROPN
fnp-3528	879	2	lipid	lipid	PROPN
fnp-3528	879	3	res	re	NOUN
fnp-3528	879	4	2006	2006	NUM
fnp-3528	879	5	,	,	PUNCT
fnp-3528	879	6	47	47	NUM
fnp-3528	879	7	,	,	PUNCT
fnp-3528	879	8	1915	1915	NUM
fnp-3528	879	9	-	-	SYM
fnp-3528	879	10	27	27	NUM
fnp-3528	879	11	.	.	PUNCT
fnp-3528	880	1	meurs	meurs	PROPN
fnp-3528	880	2	,	,	PUNCT
fnp-3528	880	3	i.	i.	NOUN
fnp-3528	880	4	;	;	PUNCT
fnp-3528	880	5	calpe	calpe	NOUN
fnp-3528	880	6	-	-	PUNCT
fnp-3528	880	7	berdiel	berdiel	ADJ
fnp-3528	880	8	,	,	PUNCT
fnp-3528	880	9	l.	l.	PROPN
fnp-3528	880	10	;	;	PUNCT
fnp-3528	880	11	habets	habet	NOUN
fnp-3528	880	12	,	,	PUNCT
fnp-3528	880	13	k.	k.	PROPN
fnp-3528	880	14	l.	l.	PROPN
fnp-3528	880	15	;	;	PUNCT
fnp-3528	880	16	zhao	zhao	PROPN
fnp-3528	880	17	,	,	PUNCT
fnp-3528	880	18	y.	y.	PROPN
fnp-3528	880	19	;	;	PUNCT
fnp-3528	880	20	korporaal	korporaal	PROPN
fnp-3528	880	21	,	,	PUNCT
fnp-3528	880	22	s.	s.	PROPN
fnp-3528	880	23	j.	j.	PROPN
fnp-3528	880	24	;	;	PUNCT
fnp-3528	880	25	mommaas	mommaas	NOUN
fnp-3528	880	26	,	,	PUNCT
fnp-3528	880	27	a.	a.	NOUN
fnp-3528	880	28	m.	m.	NOUN
fnp-3528	880	29	;	;	PUNCT
fnp-3528	880	30	josselin	josselin	PROPN
fnp-3528	880	31	,	,	PUNCT
fnp-3528	880	32	e.	e.	PROPN
fnp-3528	880	33	;	;	PUNCT
fnp-3528	880	34	hildebrand	hildebrand	PROPN
fnp-3528	880	35	,	,	PUNCT
fnp-3528	880	36	r.	r.	PROPN
fnp-3528	880	37	b.	b.	PROPN
fnp-3528	880	38	;	;	PUNCT
fnp-3528	880	39	ye	ye	PROPN
fnp-3528	880	40	,	,	PUNCT
fnp-3528	880	41	d.	d.	PROPN
fnp-3528	880	42	;	;	PUNCT
fnp-3528	880	43	out	out	ADV
fnp-3528	880	44	,	,	PUNCT
fnp-3528	880	45	r.	r.	PROPN
fnp-3528	880	46	;	;	PUNCT
fnp-3528	880	47	kuiper	kuiper	PROPN
fnp-3528	880	48	,	,	PUNCT
fnp-3528	880	49	j.	j.	PROPN
fnp-3528	880	50	;	;	PUNCT
fnp-3528	880	51	van	van	PROPN
fnp-3528	880	52	berkel	berkel	PROPN
fnp-3528	880	53	,	,	PUNCT
fnp-3528	880	54	t.	t.	PROPN
fnp-3528	880	55	j.	j.	PROPN
fnp-3528	880	56	;	;	PUNCT
fnp-3528	880	57	chimini	chimini	PROPN
fnp-3528	880	58	,	,	PUNCT
fnp-3528	880	59	g.	g.	PROPN
fnp-3528	880	60	;	;	PUNCT
fnp-3528	880	61	van	van	PROPN
fnp-3528	880	62	eck	eck	PROPN
fnp-3528	880	63	,	,	PUNCT
fnp-3528	880	64	m.	m.	NOUN
fnp-3528	880	65	effects	effect	NOUN
fnp-3528	880	66	of	of	ADP
fnp-3528	880	67	deletion	deletion	NOUN
fnp-3528	880	68	of	of	ADP
fnp-3528	880	69	macrophage	macrophage	ADJ
fnp-3528	880	70	abca7	abca7	NOUN
fnp-3528	880	71	on	on	ADP
fnp-3528	880	72	lipid	lipid	ADJ
fnp-3528	880	73	metabolism	metabolism	NOUN
fnp-3528	880	74	and	and	CCONJ
fnp-3528	880	75	the	the	DET
fnp-3528	880	76	development	development	NOUN
fnp-3528	880	77	of	of	ADP
fnp-3528	880	78	atherosclerosis	atherosclerosis	NOUN
fnp-3528	880	79	in	in	ADP
fnp-3528	880	80	the	the	DET
fnp-3528	880	81	presence	presence	NOUN
fnp-3528	880	82	and	and	CCONJ
fnp-3528	880	83	absence	absence	NOUN
fnp-3528	880	84	of	of	ADP
fnp-3528	880	85	abca1	abca1	PROPN
fnp-3528	880	86	.	.	PUNCT
fnp-3528	881	1	plos	plos	PROPN
fnp-3528	881	2	one	one	NUM
fnp-3528	881	3	2012	2012	NUM
fnp-3528	881	4	,	,	PUNCT
fnp-3528	881	5	7	7	NUM
fnp-3528	881	6	,	,	PUNCT
fnp-3528	881	7	e30984	e30984	PROPN
fnp-3528	881	8	.	.	PUNCT
fnp-3528	882	1	kim	kim	PROPN
fnp-3528	882	2	,	,	PUNCT
fnp-3528	882	3	w.	w.	PROPN
fnp-3528	882	4	s.	s.	PROPN
fnp-3528	882	5	;	;	PUNCT
fnp-3528	882	6	fitzgerald	fitzgerald	PROPN
fnp-3528	882	7	,	,	PUNCT
fnp-3528	882	8	m.	m.	PROPN
fnp-3528	882	9	l.	l.	PROPN
fnp-3528	882	10	;	;	PUNCT
fnp-3528	882	11	kang	kang	PROPN
fnp-3528	882	12	,	,	PUNCT
fnp-3528	882	13	k.	k.	PROPN
fnp-3528	882	14	;	;	PUNCT
fnp-3528	882	15	okuhira	okuhira	PROPN
fnp-3528	882	16	,	,	PUNCT
fnp-3528	882	17	k.	k.	PROPN
fnp-3528	882	18	;	;	PUNCT
fnp-3528	882	19	bell	bell	PROPN
fnp-3528	882	20	,	,	PUNCT
fnp-3528	882	21	s.	s.	PROPN
fnp-3528	882	22	a.	a.	PROPN
fnp-3528	882	23	;	;	PUNCT
fnp-3528	882	24	manning	man	VERB
fnp-3528	882	25	,	,	PUNCT
fnp-3528	882	26	j.	j.	PROPN
fnp-3528	882	27	j.	j.	PROPN
fnp-3528	882	28	;	;	PUNCT
fnp-3528	882	29	koehn	koehn	PROPN
fnp-3528	882	30	,	,	PUNCT
fnp-3528	882	31	s.	s.	PROPN
fnp-3528	882	32	l.	l.	PROPN
fnp-3528	882	33	;	;	PUNCT
fnp-3528	882	34	lu	lu	PROPN
fnp-3528	882	35	,	,	PUNCT
fnp-3528	882	36	n.	n.	PROPN
fnp-3528	882	37	;	;	PUNCT
fnp-3528	882	38	moore	moore	PROPN
fnp-3528	882	39	,	,	PUNCT
fnp-3528	882	40	k.	k.	PROPN
fnp-3528	882	41	j.	j.	PROPN
fnp-3528	882	42	;	;	PUNCT
fnp-3528	882	43	freeman	freeman	PROPN
fnp-3528	882	44	,	,	PUNCT
fnp-3528	882	45	m.	m.	PROPN
fnp-3528	882	46	w.	w.	PROPN
fnp-3528	882	47	abca7	abca7	PROPN
fnp-3528	882	48	null	null	ADJ
fnp-3528	882	49	mice	mouse	NOUN
fnp-3528	882	50	retain	retain	VERB
fnp-3528	882	51	normal	normal	ADJ
fnp-3528	882	52	macrophage	macrophage	ADJ
fnp-3528	882	53	phosphatidylcholine	phosphatidylcholine	NOUN
fnp-3528	882	54	and	and	CCONJ
fnp-3528	882	55	cholesterol	cholesterol	NOUN
fnp-3528	882	56	efflux	efflux	NOUN
fnp-3528	882	57	activity	activity	NOUN
fnp-3528	882	58	despite	despite	SCONJ
fnp-3528	882	59	alterations	alteration	NOUN
fnp-3528	882	60	in	in	ADP
fnp-3528	882	61	adipose	adipose	PRON
fnp-3528	882	62	mass	mass	NOUN
fnp-3528	882	63	and	and	CCONJ
fnp-3528	882	64	serum	serum	VERB
fnp-3528	882	65	cholesterol	cholesterol	NOUN
fnp-3528	882	66	levels	level	NOUN
fnp-3528	882	67	.	.	PUNCT
fnp-3528	883	1	j	j	PROPN
fnp-3528	883	2	biol	biol	PROPN
fnp-3528	883	3	chem	chem	NOUN
fnp-3528	883	4	2005	2005	NUM
fnp-3528	883	5	,	,	PUNCT
fnp-3528	883	6	280	280	NUM
fnp-3528	883	7	,	,	PUNCT
fnp-3528	883	8	3989	3989	NUM
fnp-3528	883	9	-	-	SYM
fnp-3528	883	10	95	95	NUM
fnp-3528	883	11	.	.	PUNCT
fnp-3528	884	1	linsel	linsel	ADJ
fnp-3528	884	2	-	-	PUNCT
fnp-3528	884	3	nitschke	nitschke	NOUN
fnp-3528	884	4	,	,	PUNCT
fnp-3528	884	5	p.	p.	PROPN
fnp-3528	884	6	;	;	PUNCT
fnp-3528	884	7	jehle	jehle	PROPN
fnp-3528	884	8	,	,	PUNCT
fnp-3528	884	9	a.	a.	PROPN
fnp-3528	884	10	w.	w.	PROPN
fnp-3528	884	11	;	;	PUNCT
fnp-3528	884	12	shan	shan	PROPN
fnp-3528	884	13	,	,	PUNCT
fnp-3528	884	14	j.	j.	PROPN
fnp-3528	884	15	;	;	PUNCT
fnp-3528	884	16	cao	cao	PROPN
fnp-3528	884	17	,	,	PUNCT
fnp-3528	884	18	g.	g.	PROPN
fnp-3528	884	19	;	;	PUNCT
fnp-3528	884	20	bacic	bacic	PROPN
fnp-3528	884	21	,	,	PUNCT
fnp-3528	884	22	d.	d.	PROPN
fnp-3528	884	23	;	;	PUNCT
fnp-3528	884	24	lan	lan	PROPN
fnp-3528	884	25	,	,	PUNCT
fnp-3528	884	26	d.	d.	PROPN
fnp-3528	884	27	;	;	PUNCT
fnp-3528	884	28	wang	wang	PROPN
fnp-3528	884	29	,	,	PUNCT
fnp-3528	884	30	n.	n.	PROPN
fnp-3528	884	31	;	;	PUNCT
fnp-3528	884	32	tall	tall	ADJ
fnp-3528	884	33	,	,	PUNCT
fnp-3528	884	34	a.	a.	PROPN
fnp-3528	884	35	r.	r.	PROPN
fnp-3528	884	36	potential	potential	ADJ
fnp-3528	884	37	role	role	NOUN
fnp-3528	884	38	of	of	ADP
fnp-3528	884	39	abca7	abca7	NOUN
fnp-3528	884	40	in	in	ADP
fnp-3528	884	41	cellular	cellular	ADJ
fnp-3528	884	42	lipid	lipid	NOUN
fnp-3528	884	43	efflux	efflux	VERB
fnp-3528	884	44	to	to	ADP
fnp-3528	884	45	apoa	apoa	NOUN
fnp-3528	884	46	-	-	PUNCT
fnp-3528	884	47	i.	i.	PROPN
fnp-3528	884	48	j	j	PROPN
fnp-3528	884	49	lipid	lipid	PROPN
fnp-3528	884	50	res	re	NOUN
fnp-3528	884	51	2005	2005	NUM
fnp-3528	884	52	,	,	PUNCT
fnp-3528	884	53	46	46	NUM
fnp-3528	884	54	,	,	PUNCT
fnp-3528	884	55	86	86	NUM
fnp-3528	884	56	-	-	SYM
fnp-3528	884	57	92	92	NUM
fnp-3528	884	58	.	.	PUNCT
fnp-3528	885	1	hollingworth	hollingworth	PROPN
fnp-3528	885	2	,	,	PUNCT
fnp-3528	885	3	p.	p.	PROPN
fnp-3528	885	4	;	;	PUNCT
fnp-3528	885	5	harold	harold	PROPN
fnp-3528	885	6	,	,	PUNCT
fnp-3528	885	7	d.	d.	PROPN
fnp-3528	885	8	;	;	PUNCT
fnp-3528	885	9	sims	sim	NOUN
fnp-3528	885	10	,	,	PUNCT
fnp-3528	885	11	r.	r.	PROPN
fnp-3528	885	12	;	;	PUNCT
fnp-3528	885	13	gerrish	gerrish	NOUN
fnp-3528	885	14	,	,	PUNCT
fnp-3528	885	15	a.	a.	NOUN
fnp-3528	885	16	;	;	PUNCT
fnp-3528	885	17	lambert	lambert	PROPN
fnp-3528	885	18	,	,	PUNCT
fnp-3528	885	19	j.	j.	PROPN
fnp-3528	885	20	c.	c.	PROPN
fnp-3528	885	21	;	;	PUNCT
fnp-3528	885	22	carrasquillo	carrasquillo	PROPN
fnp-3528	885	23	,	,	PUNCT
fnp-3528	885	24	m.	m.	NOUN
fnp-3528	885	25	m.	m.	NOUN
fnp-3528	885	26	;	;	PUNCT
fnp-3528	885	27	abraham	abraham	PROPN
fnp-3528	885	28	,	,	PUNCT
fnp-3528	885	29	r.	r.	PROPN
fnp-3528	885	30	;	;	PUNCT
fnp-3528	885	31	hamshere	hamshere	NOUN
fnp-3528	885	32	,	,	PUNCT
fnp-3528	885	33	m.	m.	NOUN
fnp-3528	885	34	l.	l.	PROPN
fnp-3528	885	35	;	;	PUNCT
fnp-3528	885	36	pahwa	pahwa	PROPN
fnp-3528	885	37	,	,	PUNCT
fnp-3528	885	38	j.	j.	PROPN
fnp-3528	885	39	s.	s.	PROPN
fnp-3528	885	40	;	;	PUNCT
fnp-3528	885	41	moskvina	moskvina	PROPN
fnp-3528	885	42	,	,	PUNCT
fnp-3528	885	43	v.	v.	ADV
fnp-3528	885	44	;	;	PUNCT
fnp-3528	885	45	dowzell	dowzell	PROPN
fnp-3528	885	46	,	,	PUNCT
fnp-3528	885	47	k.	k.	PROPN
fnp-3528	885	48	;	;	PUNCT
fnp-3528	885	49	jones	jones	PROPN
fnp-3528	885	50	,	,	PUNCT
fnp-3528	885	51	n.	n.	NOUN
fnp-3528	885	52	;	;	PUNCT
fnp-3528	885	53	stretton	stretton	PROPN
fnp-3528	885	54	,	,	PUNCT
fnp-3528	885	55	a.	a.	NOUN
fnp-3528	885	56	;	;	PUNCT
fnp-3528	885	57	thomas	thomas	PROPN
fnp-3528	885	58	,	,	PUNCT
fnp-3528	885	59	c.	c.	PROPN
fnp-3528	885	60	;	;	PUNCT
fnp-3528	885	61	richards	richard	NOUN
fnp-3528	885	62	,	,	PUNCT
fnp-3528	885	63	a.	a.	NOUN
fnp-3528	885	64	;	;	PUNCT
fnp-3528	885	65	ivanov	ivanov	PROPN
fnp-3528	885	66	,	,	PUNCT
fnp-3528	885	67	d.	d.	PROPN
fnp-3528	885	68	;	;	PUNCT
fnp-3528	885	69	widdowson	widdowson	PROPN
fnp-3528	885	70	,	,	PUNCT
fnp-3528	885	71	c.	c.	PROPN
fnp-3528	885	72	;	;	PUNCT
fnp-3528	885	73	chapman	chapman	PROPN
fnp-3528	885	74	,	,	PUNCT
fnp-3528	885	75	j.	j.	PROPN
fnp-3528	885	76	;	;	PUNCT
fnp-3528	885	77	lovestone	lovestone	NOUN
fnp-3528	885	78	,	,	PUNCT
fnp-3528	885	79	s.	s.	PROPN
fnp-3528	885	80	;	;	PUNCT
fnp-3528	885	81	powell	powell	PROPN
fnp-3528	885	82	,	,	PUNCT
fnp-3528	885	83	j.	j.	PROPN
fnp-3528	885	84	;	;	PUNCT
fnp-3528	885	85	proitsi	proitsi	PROPN
fnp-3528	885	86	,	,	PUNCT
fnp-3528	885	87	p.	p.	PROPN
fnp-3528	885	88	;	;	PUNCT
fnp-3528	885	89	lupton	lupton	PROPN
fnp-3528	885	90	,	,	PUNCT
fnp-3528	885	91	m.	m.	PROPN
fnp-3528	885	92	k.	k.	PROPN
fnp-3528	885	93	;	;	PUNCT
fnp-3528	885	94	brayne	brayne	PROPN
fnp-3528	885	95	,	,	PUNCT
fnp-3528	885	96	c.	c.	PROPN
fnp-3528	885	97	;	;	PUNCT
fnp-3528	885	98	rubinsztein	rubinsztein	PROPN
fnp-3528	885	99	,	,	PUNCT
fnp-3528	885	100	d.	d.	PROPN
fnp-3528	885	101	c.	c.	PROPN
fnp-3528	885	102	;	;	PUNCT
fnp-3528	885	103	gill	gill	NOUN
fnp-3528	885	104	,	,	PUNCT
fnp-3528	885	105	m.	m.	NOUN
fnp-3528	885	106	;	;	PUNCT
fnp-3528	885	107	lawlor	lawlor	PROPN
fnp-3528	885	108	,	,	PUNCT
fnp-3528	885	109	b.	b.	PROPN
fnp-3528	885	110	;	;	PUNCT
fnp-3528	885	111	lynch	lynch	PROPN
fnp-3528	885	112	,	,	PUNCT
fnp-3528	885	113	a.	a.	NOUN
fnp-3528	885	114	;	;	PUNCT
fnp-3528	885	115	brown	brown	PROPN
fnp-3528	885	116	,	,	PUNCT
fnp-3528	885	117	k.	k.	PROPN
fnp-3528	885	118	s.	s.	PROPN
fnp-3528	885	119	;	;	PUNCT
fnp-3528	885	120	passmore	passmore	NOUN
fnp-3528	885	121	,	,	PUNCT
fnp-3528	885	122	p.	p.	NOUN
fnp-3528	885	123	a.	a.	NOUN
fnp-3528	885	124	;	;	PUNCT
fnp-3528	885	125	craig	craig	PROPN
fnp-3528	885	126	,	,	PUNCT
fnp-3528	885	127	d.	d.	PROPN
fnp-3528	885	128	;	;	PUNCT
fnp-3528	885	129	mcguinness	mcguinness	PROPN
fnp-3528	885	130	,	,	PUNCT
fnp-3528	885	131	b.	b.	PROPN
fnp-3528	885	132	;	;	PUNCT
fnp-3528	885	133	todd	todd	PROPN
fnp-3528	885	134	,	,	PUNCT
fnp-3528	885	135	s.	s.	PROPN
fnp-3528	885	136	;	;	PUNCT
fnp-3528	885	137	holmes	holmes	PROPN
fnp-3528	885	138	,	,	PUNCT
fnp-3528	885	139	c.	c.	PROPN
fnp-3528	885	140	;	;	PUNCT
fnp-3528	885	141	mann	mann	PROPN
fnp-3528	885	142	,	,	PUNCT
fnp-3528	885	143	d.	d.	PROPN
fnp-3528	885	144	;	;	PUNCT
fnp-3528	885	145	smith	smith	PROPN
fnp-3528	885	146	,	,	PUNCT
fnp-3528	885	147	a.	a.	PROPN
fnp-3528	885	148	d.	d.	PROPN
fnp-3528	885	149	;	;	PUNCT
fnp-3528	885	150	beaumont	beaumont	PROPN
fnp-3528	885	151	,	,	PUNCT
fnp-3528	885	152	h.	h.	PROPN
fnp-3528	885	153	;	;	PUNCT
fnp-3528	885	154	warden	warden	PROPN
fnp-3528	885	155	,	,	PUNCT
fnp-3528	885	156	d.	d.	PROPN
fnp-3528	885	157	;	;	PUNCT
fnp-3528	885	158	wilcock	wilcock	PROPN
fnp-3528	885	159	,	,	PUNCT
fnp-3528	885	160	g.	g.	PROPN
fnp-3528	885	161	;	;	PUNCT
fnp-3528	885	162	love	love	PROPN
fnp-3528	885	163	,	,	PUNCT
fnp-3528	885	164	s.	s.	PROPN
fnp-3528	885	165	;	;	PUNCT
fnp-3528	885	166	kehoe	kehoe	PROPN
fnp-3528	885	167	,	,	PUNCT
fnp-3528	885	168	p.	p.	PROPN
fnp-3528	885	169	g.	g.	PROPN
fnp-3528	885	170	;	;	PUNCT
fnp-3528	885	171	hooper	hooper	PROPN
fnp-3528	885	172	,	,	PUNCT
fnp-3528	885	173	n.	n.	PROPN
fnp-3528	885	174	m.	m.	NOUN
fnp-3528	885	175	;	;	PUNCT
fnp-3528	885	176	vardy	vardy	NOUN
fnp-3528	885	177	,	,	PUNCT
fnp-3528	885	178	e.	e.	PROPN
fnp-3528	885	179	r.	r.	PROPN
fnp-3528	885	180	;	;	PUNCT
fnp-3528	885	181	hardy	hardy	ADJ
fnp-3528	885	182	,	,	PUNCT
fnp-3528	885	183	j.	j.	PROPN
fnp-3528	885	184	;	;	PUNCT
fnp-3528	885	185	mead	mead	PROPN
fnp-3528	885	186	,	,	PUNCT
fnp-3528	885	187	s.	s.	PROPN
fnp-3528	885	188	;	;	PUNCT
fnp-3528	885	189	fox	fox	PROPN
fnp-3528	885	190	,	,	PUNCT
fnp-3528	885	191	n.	n.	PROPN
fnp-3528	885	192	c.	c.	PROPN
fnp-3528	885	193	;	;	PUNCT
fnp-3528	885	194	rossor	rossor	NOUN
fnp-3528	885	195	,	,	PUNCT
fnp-3528	885	196	m.	m.	NOUN
fnp-3528	885	197	;	;	PUNCT
fnp-3528	885	198	collinge	collinge	NOUN
fnp-3528	885	199	,	,	PUNCT
fnp-3528	885	200	j.	j.	PROPN
fnp-3528	885	201	;	;	PUNCT
fnp-3528	885	202	maier	maier	PROPN
fnp-3528	885	203	,	,	PUNCT
fnp-3528	885	204	w.	w.	PROPN
fnp-3528	885	205	;	;	PUNCT
fnp-3528	885	206	jessen	jessen	PROPN
fnp-3528	885	207	,	,	PUNCT
fnp-3528	885	208	f.	f.	PROPN
fnp-3528	885	209	;	;	PUNCT
fnp-3528	885	210	ruther	ruther	PROPN
fnp-3528	885	211	,	,	PUNCT
fnp-3528	885	212	e.	e.	PROPN
fnp-3528	885	213	;	;	PUNCT
fnp-3528	885	214	schurmann	schurmann	PROPN
fnp-3528	885	215	,	,	PUNCT
fnp-3528	885	216	b.	b.	PROPN
fnp-3528	885	217	;	;	PUNCT
fnp-3528	885	218	heun	heun	PROPN
fnp-3528	885	219	,	,	PUNCT
fnp-3528	885	220	r.	r.	PROPN
fnp-3528	885	221	;	;	PUNCT
fnp-3528	885	222	kolsch	kolsch	PROPN
fnp-3528	885	223	,	,	PUNCT
fnp-3528	885	224	h.	h.	PROPN
fnp-3528	885	225	;	;	PUNCT
fnp-3528	885	226	van	van	PROPN
fnp-3528	885	227	den	den	PROPN
fnp-3528	885	228	bussche	bussche	PROPN
fnp-3528	885	229	,	,	PUNCT
fnp-3528	885	230	h.	h.	PROPN
fnp-3528	885	231	;	;	PUNCT
fnp-3528	885	232	heuser	heuser	PROPN
fnp-3528	885	233	,	,	PUNCT
fnp-3528	885	234	i.	i.	PROPN
fnp-3528	885	235	;	;	PUNCT
fnp-3528	885	236	kornhuber	kornhuber	PROPN
fnp-3528	885	237	,	,	PUNCT
fnp-3528	885	238	j.	j.	PROPN
fnp-3528	885	239	;	;	PUNCT
fnp-3528	885	240	wiltfang	wiltfang	PROPN
fnp-3528	885	241	,	,	PUNCT
fnp-3528	885	242	j.	j.	PROPN
fnp-3528	885	243	;	;	PUNCT
fnp-3528	885	244	dichgans	dichgan	NOUN
fnp-3528	885	245	,	,	PUNCT
fnp-3528	885	246	m.	m.	NOUN
fnp-3528	885	247	;	;	PUNCT
fnp-3528	885	248	frolich	frolich	ADV
fnp-3528	885	249	,	,	PUNCT
fnp-3528	885	250	l.	l.	PROPN
fnp-3528	885	251	;	;	PUNCT
fnp-3528	885	252	hampel	hampel	PROPN
fnp-3528	885	253	,	,	PUNCT
fnp-3528	885	254	h.	h.	PROPN
fnp-3528	885	255	;	;	PUNCT
fnp-3528	885	256	gallacher	gallacher	PROPN
fnp-3528	885	257	,	,	PUNCT
fnp-3528	885	258	j.	j.	PROPN
fnp-3528	885	259	;	;	PUNCT
fnp-3528	885	260	hull	hull	NOUN
fnp-3528	885	261	,	,	PUNCT
fnp-3528	885	262	m.	m.	NOUN
fnp-3528	885	263	;	;	PUNCT
fnp-3528	885	264	rujescu	rujescu	NOUN
fnp-3528	885	265	,	,	PUNCT
fnp-3528	885	266	d.	d.	PROPN
fnp-3528	885	267	;	;	PUNCT
fnp-3528	885	268	giegling	giegling	NOUN
fnp-3528	885	269	,	,	PUNCT
fnp-3528	885	270	i.	i.	NOUN
fnp-3528	885	271	;	;	PUNCT
fnp-3528	885	272	goate	goate	NOUN
fnp-3528	885	273	,	,	PUNCT
fnp-3528	885	274	a.	a.	NOUN
fnp-3528	885	275	m.	m.	NOUN
fnp-3528	885	276	;	;	PUNCT
fnp-3528	885	277	kauwe	kauwe	PROPN
fnp-3528	885	278	,	,	PUNCT
fnp-3528	885	279	j.	j.	PROPN
fnp-3528	885	280	s.	s.	PROPN
fnp-3528	885	281	;	;	PUNCT
fnp-3528	885	282	cruchaga	cruchaga	NOUN
fnp-3528	885	283	,	,	PUNCT
fnp-3528	885	284	c.	c.	PROPN
fnp-3528	885	285	;	;	PUNCT
fnp-3528	885	286	nowotny	nowotny	NOUN
fnp-3528	885	287	,	,	PUNCT
fnp-3528	885	288	p.	p.	PROPN
fnp-3528	885	289	;	;	PUNCT
fnp-3528	885	290	morris	morris	PROPN
fnp-3528	885	291	,	,	PUNCT
fnp-3528	885	292	j.	j.	PROPN
fnp-3528	885	293	c.	c.	PROPN
fnp-3528	885	294	;	;	PUNCT
fnp-3528	885	295	mayo	mayo	NOUN
fnp-3528	885	296	,	,	PUNCT
fnp-3528	885	297	k.	k.	PROPN
fnp-3528	885	298	;	;	PUNCT
fnp-3528	885	299	sleegers	sleeger	NOUN
fnp-3528	885	300	,	,	PUNCT
fnp-3528	885	301	k.	k.	PROPN
fnp-3528	885	302	;	;	PUNCT
fnp-3528	885	303	bettens	betten	NOUN
fnp-3528	885	304	,	,	PUNCT
fnp-3528	885	305	k.	k.	PROPN
fnp-3528	885	306	;	;	PUNCT
fnp-3528	885	307	engelborghs	engelborghs	VERB
fnp-3528	885	308	,	,	PUNCT
fnp-3528	885	309	s.	s.	PROPN
fnp-3528	885	310	;	;	PUNCT
fnp-3528	885	311	de	de	X
fnp-3528	885	312	deyn	deyn	NOUN
fnp-3528	885	313	,	,	PUNCT
fnp-3528	886	1	p.	p.	PROPN
fnp-3528	886	2	p.	p.	NOUN
fnp-3528	886	3	;	;	PUNCT
fnp-3528	886	4	van	van	PROPN
fnp-3528	886	5	broeckhoven	broeckhoven	PROPN
fnp-3528	886	6	,	,	PUNCT
fnp-3528	886	7	c.	c.	PROPN
fnp-3528	886	8	;	;	PUNCT
fnp-3528	886	9	livingston	livingston	PROPN
fnp-3528	886	10	,	,	PUNCT
fnp-3528	886	11	g.	g.	PROPN
fnp-3528	886	12	;	;	PUNCT
fnp-3528	886	13	bass	bass	NOUN
fnp-3528	886	14	,	,	PUNCT
fnp-3528	886	15	n.	n.	PROPN
fnp-3528	886	16	j.	j.	PROPN
fnp-3528	886	17	;	;	PUNCT
fnp-3528	886	18	gurling	gurle	VERB
fnp-3528	886	19	,	,	PUNCT
fnp-3528	886	20	h.	h.	PROPN
fnp-3528	886	21	;	;	PUNCT
fnp-3528	886	22	mcquillin	mcquillin	PROPN
fnp-3528	886	23	,	,	PUNCT
fnp-3528	886	24	a.	a.	NOUN
fnp-3528	886	25	;	;	PUNCT
fnp-3528	886	26	gwilliam	gwilliam	PROPN
fnp-3528	886	27	,	,	PUNCT
fnp-3528	886	28	r.	r.	PROPN
fnp-3528	886	29	;	;	PUNCT
fnp-3528	886	30	deloukas	deloukas	PROPN
fnp-3528	886	31	,	,	PUNCT
fnp-3528	886	32	p.	p.	NOUN
fnp-3528	886	33	;	;	PUNCT
fnp-3528	886	34	al	al	PROPN
fnp-3528	886	35	-	-	PUNCT
fnp-3528	886	36	chalabi	chalabi	PROPN
fnp-3528	886	37	,	,	PUNCT
fnp-3528	886	38	a.	a.	NOUN
fnp-3528	886	39	;	;	PUNCT
fnp-3528	886	40	shaw	shaw	PROPN
fnp-3528	886	41	,	,	PUNCT
fnp-3528	886	42	c.	c.	PROPN
fnp-3528	886	43	e.	e.	PROPN
fnp-3528	886	44	;	;	PUNCT
fnp-3528	886	45	tsolaki	tsolaki	NOUN
fnp-3528	886	46	,	,	PUNCT
fnp-3528	886	47	m.	m.	NOUN
fnp-3528	886	48	;	;	PUNCT
fnp-3528	886	49	singleton	singleton	PROPN
fnp-3528	886	50	,	,	PUNCT
fnp-3528	886	51	a.	a.	PROPN
fnp-3528	886	52	b.	b.	PROPN
fnp-3528	886	53	;	;	PUNCT
fnp-3528	886	54	guerreiro	guerreiro	PROPN
fnp-3528	886	55	,	,	PUNCT
fnp-3528	886	56	r.	r.	PROPN
fnp-3528	886	57	;	;	PUNCT
fnp-3528	886	58	muhleisen	muhleisen	PROPN
fnp-3528	886	59	,	,	PUNCT
fnp-3528	886	60	t.	t.	PROPN
fnp-3528	886	61	w.	w.	PROPN
fnp-3528	886	62	;	;	PUNCT
fnp-3528	886	63	nothen	nothen	ADV
fnp-3528	886	64	,	,	PUNCT
fnp-3528	886	65	m.	m.	NOUN
fnp-3528	886	66	m.	m.	NOUN
fnp-3528	886	67	;	;	PUNCT
fnp-3528	886	68	moebus	moebus	NOUN
fnp-3528	886	69	,	,	PUNCT
fnp-3528	886	70	s.	s.	PROPN
fnp-3528	886	71	;	;	PUNCT
fnp-3528	886	72	jockel	jockel	NOUN
fnp-3528	886	73	,	,	PUNCT
fnp-3528	886	74	k.	k.	PROPN
fnp-3528	886	75	h.	h.	PROPN
fnp-3528	886	76	;	;	PUNCT
fnp-3528	886	77	klopp	klopp	PROPN
fnp-3528	886	78	,	,	PUNCT
fnp-3528	886	79	n.	n.	NOUN
fnp-3528	886	80	;	;	PUNCT
fnp-3528	886	81	wichmann	wichmann	PROPN
fnp-3528	886	82	,	,	PUNCT
fnp-3528	886	83	h.	h.	PROPN
fnp-3528	886	84	e.	e.	PROPN
fnp-3528	886	85	;	;	PUNCT
fnp-3528	886	86	pankratz	pankratz	NOUN
fnp-3528	886	87	,	,	PUNCT
fnp-3528	886	88	v.	v.	PROPN
fnp-3528	886	89	s.	s.	PROPN
fnp-3528	886	90	;	;	PUNCT
fnp-3528	886	91	sando	sando	PROPN
fnp-3528	886	92	,	,	PUNCT
fnp-3528	886	93	s.	s.	PROPN
fnp-3528	886	94	b.	b.	PROPN
fnp-3528	886	95	;	;	PUNCT
fnp-3528	886	96	aasly	aasly	ADV
fnp-3528	886	97	,	,	PUNCT
fnp-3528	886	98	j.	j.	PROPN
fnp-3528	886	99	o.	o.	PROPN
fnp-3528	886	100	;	;	PUNCT
fnp-3528	886	101	barcikowska	barcikowska	PROPN
fnp-3528	886	102	,	,	PUNCT
fnp-3528	886	103	m.	m.	NOUN
fnp-3528	886	104	;	;	PUNCT
fnp-3528	886	105	wszolek	wszolek	PROPN
fnp-3528	886	106	,	,	PUNCT
fnp-3528	886	107	z.	z.	PROPN
fnp-3528	886	108	k.	k.	PROPN
fnp-3528	886	109	;	;	PUNCT
fnp-3528	886	110	dickson	dickson	PROPN
fnp-3528	886	111	,	,	PUNCT
fnp-3528	886	112	d.	d.	PROPN
fnp-3528	886	113	w.	w.	PROPN
fnp-3528	886	114	;	;	PUNCT
fnp-3528	886	115	graff	graff	NOUN
fnp-3528	886	116	-	-	PUNCT
fnp-3528	886	117	radford	radford	PROPN
fnp-3528	886	118	,	,	PUNCT
fnp-3528	886	119	n.	n.	PROPN
fnp-3528	886	120	r.	r.	PROPN
fnp-3528	886	121	;	;	PUNCT
fnp-3528	886	122	petersen	petersen	PROPN
fnp-3528	886	123	,	,	PUNCT
fnp-3528	886	124	r.	r.	PROPN
fnp-3528	886	125	c.	c.	PROPN
fnp-3528	886	126	;	;	PUNCT
fnp-3528	886	127	alzheimer	alzheimer	PROPN
fnp-3528	886	128	's	's	PART
fnp-3528	886	129	disease	disease	NOUN
fnp-3528	886	130	neuroimaging	neuroimaging	NOUN
fnp-3528	886	131	,	,	PUNCT
fnp-3528	886	132	i.	i.	NOUN
fnp-3528	886	133	;	;	PUNCT
fnp-3528	886	134	van	van	PROPN
fnp-3528	886	135	duijn	duijn	PROPN
fnp-3528	886	136	,	,	PUNCT
fnp-3528	886	137	c.	c.	PROPN
fnp-3528	886	138	m.	m.	NOUN
fnp-3528	886	139	;	;	PUNCT
fnp-3528	886	140	breteler	breteler	NOUN
fnp-3528	886	141	,	,	PUNCT
fnp-3528	886	142	m.	m.	NOUN
fnp-3528	886	143	m.	m.	NOUN
fnp-3528	886	144	;	;	PUNCT
fnp-3528	886	145	ikram	ikram	NOUN
fnp-3528	886	146	,	,	PUNCT
fnp-3528	886	147	m.	m.	NOUN
fnp-3528	886	148	a.	a.	PROPN
fnp-3528	886	149	;	;	PUNCT
fnp-3528	886	150	destefano	destefano	NOUN
fnp-3528	886	151	,	,	PUNCT
fnp-3528	886	152	a.	a.	PROPN
fnp-3528	886	153	l.	l.	PROPN
fnp-3528	886	154	;	;	PUNCT
fnp-3528	886	155	fitzpatrick	fitzpatrick	PROPN
fnp-3528	886	156	,	,	PUNCT
fnp-3528	886	157	a.	a.	PROPN
fnp-3528	886	158	l.	l.	PROPN
fnp-3528	886	159	;	;	PUNCT
fnp-3528	886	160	lopez	lopez	NOUN
fnp-3528	886	161	,	,	PUNCT
fnp-3528	886	162	o.	o.	PROPN
fnp-3528	886	163	;	;	PUNCT
fnp-3528	886	164	launer	launer	PROPN
fnp-3528	886	165	,	,	PUNCT
fnp-3528	886	166	l.	l.	PROPN
fnp-3528	886	167	j.	j.	PROPN
fnp-3528	886	168	;	;	PUNCT
fnp-3528	886	169	seshadri	seshadri	PROPN
fnp-3528	886	170	,	,	PUNCT
fnp-3528	886	171	s.	s.	PROPN
fnp-3528	886	172	;	;	PUNCT
fnp-3528	886	173	consortium	consortium	NOUN
fnp-3528	886	174	,	,	PUNCT
fnp-3528	886	175	c.	c.	PROPN
fnp-3528	886	176	;	;	PUNCT
fnp-3528	886	177	berr	berr	PROPN
fnp-3528	886	178	,	,	PUNCT
fnp-3528	886	179	c.	c.	PROPN
fnp-3528	886	180	;	;	PUNCT
fnp-3528	886	181	campion	campion	NOUN
fnp-3528	886	182	,	,	PUNCT
fnp-3528	886	183	d.	d.	PROPN
fnp-3528	886	184	;	;	PUNCT
fnp-3528	886	185	epelbaum	epelbaum	PROPN
fnp-3528	886	186	,	,	PUNCT
fnp-3528	886	187	j.	j.	PROPN
fnp-3528	886	188	;	;	PUNCT
fnp-3528	886	189	dartigues	dartigue	NOUN
fnp-3528	886	190	,	,	PUNCT
fnp-3528	886	191	j.	j.	PROPN
fnp-3528	886	192	f.	f.	PROPN
fnp-3528	886	193	;	;	PUNCT
fnp-3528	886	194	tzourio	tzourio	PROPN
fnp-3528	886	195	,	,	PUNCT
fnp-3528	886	196	c.	c.	PROPN
fnp-3528	886	197	;	;	PUNCT
fnp-3528	886	198	alperovitch	alperovitch	PROPN
fnp-3528	886	199	,	,	PUNCT
fnp-3528	886	200	a.	a.	NOUN
fnp-3528	886	201	;	;	PUNCT
fnp-3528	886	202	lathrop	lathrop	PROPN
fnp-3528	886	203	,	,	PUNCT
fnp-3528	886	204	m.	m.	NOUN
fnp-3528	886	205	;	;	PUNCT
fnp-3528	886	206	consortium	consortium	NOUN
fnp-3528	886	207	,	,	PUNCT
fnp-3528	886	208	e.	e.	PROPN
fnp-3528	886	209	;	;	PUNCT
fnp-3528	886	210	feulner	feulner	NOUN
fnp-3528	886	211	,	,	PUNCT
fnp-3528	886	212	t.	t.	NOUN
fnp-3528	886	213	m.	m.	NOUN
fnp-3528	886	214	;	;	PUNCT
fnp-3528	886	215	friedrich	friedrich	PROPN
fnp-3528	886	216	,	,	PUNCT
fnp-3528	886	217	p.	p.	NOUN
fnp-3528	886	218	;	;	PUNCT
fnp-3528	887	1	riehle	riehle	ADJ
fnp-3528	887	2	,	,	PUNCT
fnp-3528	887	3	c.	c.	NOUN
fnp-3528	887	4	;	;	PUNCT
fnp-3528	887	5	krawczak	krawczak	PROPN
fnp-3528	887	6	,	,	PUNCT
fnp-3528	887	7	m.	m.	NOUN
fnp-3528	887	8	;	;	PUNCT
fnp-3528	887	9	schreiber	schreiber	PROPN
fnp-3528	887	10	,	,	PUNCT
fnp-3528	887	11	s.	s.	PROPN
fnp-3528	887	12	;	;	PUNCT
fnp-3528	887	13	mayhaus	mayhaus	PROPN
fnp-3528	887	14	,	,	PUNCT
fnp-3528	887	15	m.	m.	NOUN
fnp-3528	887	16	;	;	PUNCT
fnp-3528	887	17	nicolhaus	nicolhaus	PROPN
fnp-3528	887	18	,	,	PUNCT
fnp-3528	887	19	s.	s.	PROPN
fnp-3528	887	20	;	;	PUNCT
fnp-3528	887	21	wagenpfeil	wagenpfeil	PROPN
fnp-3528	887	22	,	,	PUNCT
fnp-3528	887	23	s.	s.	PROPN
fnp-3528	887	24	;	;	PUNCT
fnp-3528	887	25	steinberg	steinberg	PROPN
fnp-3528	887	26	,	,	PUNCT
fnp-3528	887	27	s.	s.	PROPN
fnp-3528	887	28	;	;	PUNCT
fnp-3528	887	29	stefansson	stefansson	PROPN
fnp-3528	887	30	,	,	PUNCT
fnp-3528	887	31	h.	h.	PROPN
fnp-3528	887	32	;	;	PUNCT
fnp-3528	887	33	stefansson	stefansson	PROPN
fnp-3528	887	34	,	,	PUNCT
fnp-3528	887	35	k.	k.	PROPN
fnp-3528	887	36	;	;	PUNCT
fnp-3528	887	37	snaedal	snaedal	PROPN
fnp-3528	887	38	,	,	PUNCT
fnp-3528	887	39	j.	j.	PROPN
fnp-3528	887	40	;	;	PUNCT
fnp-3528	887	41	bjornsson	bjornsson	PROPN
fnp-3528	887	42	,	,	PUNCT
fnp-3528	887	43	s.	s.	PROPN
fnp-3528	887	44	;	;	PUNCT
fnp-3528	887	45	jonsson	jonsson	PROPN
fnp-3528	887	46	,	,	PUNCT
fnp-3528	887	47	p.	p.	NOUN
fnp-3528	887	48	v.	v.	PROPN
fnp-3528	887	49	;	;	PUNCT
fnp-3528	887	50	chouraki	chouraki	VERB
fnp-3528	887	51	,	,	PUNCT
fnp-3528	887	52	v.	v.	ADV
fnp-3528	887	53	;	;	PUNCT
fnp-3528	887	54	genier	genier	NOUN
fnp-3528	887	55	-	-	PUNCT
fnp-3528	887	56	boley	boley	PROPN
fnp-3528	887	57	,	,	PUNCT
fnp-3528	887	58	b.	b.	PROPN
fnp-3528	887	59	;	;	PUNCT
fnp-3528	887	60	hiltunen	hiltunen	PROPN
fnp-3528	887	61	,	,	PUNCT
fnp-3528	887	62	m.	m.	NOUN
fnp-3528	887	63	;	;	PUNCT
fnp-3528	887	64	soininen	soininen	PROPN
fnp-3528	887	65	,	,	PUNCT
fnp-3528	887	66	h.	h.	PROPN
fnp-3528	887	67	;	;	PUNCT
fnp-3528	887	68	combarros	combarro	NOUN
fnp-3528	887	69	,	,	PUNCT
fnp-3528	887	70	o.	o.	INTJ
fnp-3528	887	71	;	;	PUNCT
fnp-3528	887	72	zelenika	zelenika	PROPN
fnp-3528	887	73	,	,	PUNCT
fnp-3528	887	74	d.	d.	PROPN
fnp-3528	887	75	;	;	PUNCT
fnp-3528	887	76	delepine	delepine	ADJ
fnp-3528	887	77	,	,	PUNCT
fnp-3528	887	78	m.	m.	NOUN
fnp-3528	887	79	;	;	PUNCT
fnp-3528	887	80	bullido	bullido	ADJ
fnp-3528	887	81	,	,	PUNCT
fnp-3528	887	82	m.	m.	NOUN
fnp-3528	887	83	j.	j.	PROPN
fnp-3528	887	84	;	;	PUNCT
fnp-3528	887	85	pasquier	pasquier	PROPN
fnp-3528	887	86	,	,	PUNCT
fnp-3528	887	87	f.	f.	PROPN
fnp-3528	887	88	;	;	PUNCT
fnp-3528	887	89	mateo	mateo	PROPN
fnp-3528	887	90	,	,	PUNCT
fnp-3528	887	91	i.	i.	PROPN
fnp-3528	887	92	;	;	PUNCT
fnp-3528	887	93	frank	frank	PROPN
fnp-3528	887	94	-	-	PUNCT
fnp-3528	887	95	garcia	garcia	PROPN
fnp-3528	887	96	,	,	PUNCT
fnp-3528	887	97	a.	a.	NOUN
fnp-3528	887	98	;	;	PUNCT
fnp-3528	887	99	porcellini	porcellini	PROPN
fnp-3528	887	100	,	,	PUNCT
fnp-3528	887	101	e.	e.	PROPN
fnp-3528	887	102	;	;	PUNCT
fnp-3528	887	103	hanon	hanon	PROPN
fnp-3528	887	104	,	,	PUNCT
fnp-3528	887	105	o.	o.	PROPN
fnp-3528	887	106	;	;	PUNCT
fnp-3528	887	107	coto	coto	PROPN
fnp-3528	887	108	,	,	PUNCT
fnp-3528	887	109	e.	e.	PROPN
fnp-3528	887	110	;	;	PUNCT
fnp-3528	887	111	alvarez	alvarez	PROPN
fnp-3528	887	112	,	,	PUNCT
fnp-3528	887	113	v.	v.	PROPN
fnp-3528	887	114	;	;	PUNCT
fnp-3528	887	115	bosco	bosco	PROPN
fnp-3528	887	116	,	,	PUNCT
fnp-3528	887	117	p.	p.	PROPN
fnp-3528	887	118	;	;	PUNCT
fnp-3528	887	119	siciliano	siciliano	PROPN
fnp-3528	887	120	,	,	PUNCT
fnp-3528	887	121	g.	g.	PROPN
fnp-3528	887	122	;	;	PUNCT
fnp-3528	887	123	mancuso	mancuso	PROPN
fnp-3528	887	124	,	,	PUNCT
fnp-3528	887	125	m.	m.	NOUN
fnp-3528	887	126	;	;	PUNCT
fnp-3528	887	127	panza	panza	PROPN
fnp-3528	887	128	,	,	PUNCT
fnp-3528	887	129	f.	f.	PROPN
fnp-3528	887	130	;	;	PUNCT
fnp-3528	887	131	solfrizzi	solfrizzi	PROPN
fnp-3528	887	132	,	,	PUNCT
fnp-3528	887	133	v.	v.	PROPN
fnp-3528	887	134	;	;	PUNCT
fnp-3528	887	135	nacmias	nacmias	PROPN
fnp-3528	887	136	,	,	PUNCT
fnp-3528	887	137	b.	b.	PROPN
fnp-3528	887	138	;	;	PUNCT
fnp-3528	887	139	sorbi	sorbi	PROPN
fnp-3528	887	140	,	,	PUNCT
fnp-3528	887	141	s.	s.	PROPN
fnp-3528	887	142	;	;	PUNCT
fnp-3528	887	143	bossu	bossu	PROPN
fnp-3528	887	144	,	,	PUNCT
fnp-3528	887	145	p.	p.	PROPN
fnp-3528	887	146	;	;	PUNCT
fnp-3528	887	147	piccardi	piccardi	VERB
fnp-3528	887	148	,	,	PUNCT
fnp-3528	887	149	p.	p.	NOUN
fnp-3528	887	150	;	;	PUNCT
fnp-3528	887	151	arosio	arosio	PROPN
fnp-3528	887	152	,	,	PUNCT
fnp-3528	887	153	b.	b.	PROPN
fnp-3528	887	154	;	;	PUNCT
fnp-3528	887	155	annoni	annoni	PROPN
fnp-3528	887	156	,	,	PUNCT
fnp-3528	887	157	g.	g.	PROPN
fnp-3528	887	158	;	;	PUNCT
fnp-3528	887	159	seripa	seripa	PROPN
fnp-3528	887	160	,	,	PUNCT
fnp-3528	887	161	d.	d.	PROPN
fnp-3528	887	162	;	;	PUNCT
fnp-3528	887	163	pilotto	pilotto	NOUN
fnp-3528	887	164	,	,	PUNCT
fnp-3528	887	165	a.	a.	NOUN
fnp-3528	887	166	;	;	PUNCT
fnp-3528	887	167	scarpini	scarpini	PROPN
fnp-3528	887	168	,	,	PUNCT
fnp-3528	887	169	e.	e.	PROPN
fnp-3528	887	170	;	;	PUNCT
fnp-3528	887	171	galimberti	galimberti	PROPN
fnp-3528	887	172	,	,	PUNCT
fnp-3528	887	173	d.	d.	PROPN
fnp-3528	887	174	;	;	PUNCT
fnp-3528	887	175	brice	brice	PROPN
fnp-3528	887	176	,	,	PUNCT
fnp-3528	887	177	a.	a.	PROPN
fnp-3528	887	178	;	;	PUNCT
fnp-3528	887	179	hannequin	hannequin	PROPN
fnp-3528	887	180	,	,	PUNCT
fnp-3528	887	181	d.	d.	PROPN
fnp-3528	887	182	;	;	PUNCT
fnp-3528	887	183	licastro	licastro	PROPN
fnp-3528	887	184	,	,	PUNCT
fnp-3528	887	185	f.	f.	PROPN
fnp-3528	887	186	;	;	PUNCT
fnp-3528	887	187	jones	jones	PROPN
fnp-3528	887	188	,	,	PUNCT
fnp-3528	887	189	l.	l.	PROPN
fnp-3528	887	190	;	;	PUNCT
fnp-3528	887	191	holmans	holman	NOUN
fnp-3528	887	192	,	,	PUNCT
fnp-3528	887	193	p.	p.	NOUN
fnp-3528	887	194	a.	a.	NOUN
fnp-3528	887	195	;	;	PUNCT
fnp-3528	887	196	jonsson	jonsson	PROPN
fnp-3528	887	197	,	,	PUNCT
fnp-3528	887	198	t.	t.	PROPN
fnp-3528	887	199	;	;	PUNCT
fnp-3528	887	200	riemenschneider	riemenschneider	PROPN
fnp-3528	887	201	,	,	PUNCT
fnp-3528	887	202	m.	m.	NOUN
fnp-3528	887	203	;	;	PUNCT
fnp-3528	887	204	morgan	morgan	PROPN
fnp-3528	887	205	,	,	PUNCT
fnp-3528	887	206	k.	k.	PROPN
fnp-3528	887	207	;	;	PUNCT
fnp-3528	887	208	younkin	younkin	PROPN
fnp-3528	887	209	,	,	PUNCT
fnp-3528	887	210	s.	s.	PROPN
fnp-3528	887	211	g.	g.	PROPN
fnp-3528	887	212	;	;	PUNCT
fnp-3528	887	213	owen	owen	PROPN
fnp-3528	887	214	,	,	PUNCT
fnp-3528	887	215	m.	m.	PROPN
fnp-3528	887	216	j.	j.	PROPN
fnp-3528	887	217	;	;	PUNCT
fnp-3528	887	218	o'donovan	o'donovan	PROPN
fnp-3528	887	219	,	,	PUNCT
fnp-3528	887	220	m.	m.	NOUN
fnp-3528	887	221	;	;	PUNCT
fnp-3528	887	222	amouyel	amouyel	PROPN
fnp-3528	887	223	,	,	PUNCT
fnp-3528	887	224	p.	p.	NOUN
fnp-3528	887	225	;	;	PUNCT
fnp-3528	887	226	williams	williams	PROPN
fnp-3528	887	227	,	,	PUNCT
fnp-3528	887	228	j.	j.	PROPN
fnp-3528	887	229	common	common	ADJ
fnp-3528	887	230	variants	variant	NOUN
fnp-3528	887	231	at	at	ADP
fnp-3528	887	232	abca7	abca7	PROPN
fnp-3528	887	233	,	,	PUNCT
fnp-3528	887	234	ms4a6a	ms4a6a	PROPN
fnp-3528	887	235	/	/	SYM
fnp-3528	887	236	ms4a4e	ms4a4e	PROPN
fnp-3528	887	237	,	,	PUNCT
fnp-3528	887	238	epha1	epha1	PROPN
fnp-3528	887	239	,	,	PUNCT
fnp-3528	887	240	cd33	cd33	PROPN
fnp-3528	887	241	and	and	CCONJ
fnp-3528	887	242	cd2ap	cd2ap	NOUN
fnp-3528	887	243	are	be	AUX
fnp-3528	887	244	associated	associate	VERB
fnp-3528	887	245	with	with	ADP
fnp-3528	887	246	alzheimer	alzheimer	PROPN
fnp-3528	887	247	's	's	PART
fnp-3528	887	248	disease	disease	NOUN
fnp-3528	887	249	.	.	PUNCT
fnp-3528	888	1	nat	nat	PROPN
fnp-3528	888	2	genet	genet	PROPN
fnp-3528	888	3	2011	2011	NUM
fnp-3528	888	4	,	,	PUNCT
fnp-3528	888	5	43	43	NUM
fnp-3528	888	6	,	,	PUNCT
fnp-3528	888	7	429	429	NUM
fnp-3528	888	8	-	-	SYM
fnp-3528	888	9	35	35	NUM
fnp-3528	888	10	.	.	PUNCT
fnp-3528	889	1	vasquez	vasquez	PROPN
fnp-3528	889	2	,	,	PUNCT
fnp-3528	889	3	j.	j.	PROPN
fnp-3528	889	4	b.	b.	PROPN
fnp-3528	889	5	;	;	PUNCT
fnp-3528	889	6	simpson	simpson	PROPN
fnp-3528	889	7	,	,	PUNCT
fnp-3528	889	8	j.	j.	PROPN
fnp-3528	889	9	f.	f.	PROPN
fnp-3528	889	10	;	;	PUNCT
fnp-3528	889	11	harpole	harpole	PROPN
fnp-3528	889	12	,	,	PUNCT
fnp-3528	889	13	r.	r.	PROPN
fnp-3528	889	14	;	;	PUNCT
fnp-3528	889	15	estus	estus	PROPN
fnp-3528	889	16	,	,	PUNCT
fnp-3528	889	17	s.	s.	PROPN
fnp-3528	889	18	alzheimer	alzheimer	PROPN
fnp-3528	889	19	's	's	PART
fnp-3528	889	20	disease	disease	NOUN
fnp-3528	889	21	genetics	genetic	NOUN
fnp-3528	889	22	and	and	CCONJ
fnp-3528	889	23	abca7	abca7	PROPN
fnp-3528	889	24	splicing	splicing	NOUN
fnp-3528	889	25	.	.	PUNCT
fnp-3528	890	1	j	j	PROPN
fnp-3528	890	2	alzheimers	alzheimers	PROPN
fnp-3528	890	3	dis	dis	PROPN
fnp-3528	890	4	2017	2017	NUM
fnp-3528	890	5	,	,	PUNCT
fnp-3528	890	6	59	59	NUM
fnp-3528	890	7	,	,	PUNCT
fnp-3528	890	8	633	633	NUM
fnp-3528	890	9	-	-	SYM
fnp-3528	890	10	41	41	NUM
fnp-3528	890	11	.	.	PUNCT
fnp-3528	891	1	karch	karch	PROPN
fnp-3528	891	2	,	,	PUNCT
fnp-3528	891	3	c.	c.	PROPN
fnp-3528	891	4	m.	m.	NOUN
fnp-3528	891	5	;	;	PUNCT
fnp-3528	891	6	jeng	jeng	PROPN
fnp-3528	891	7	,	,	PUNCT
fnp-3528	891	8	a.	a.	PROPN
fnp-3528	891	9	t.	t.	PROPN
fnp-3528	891	10	;	;	PUNCT
fnp-3528	891	11	nowotny	nowotny	NOUN
fnp-3528	891	12	,	,	PUNCT
fnp-3528	891	13	p.	p.	PROPN
fnp-3528	891	14	;	;	PUNCT
fnp-3528	891	15	cady	cady	PROPN
fnp-3528	891	16	,	,	PUNCT
fnp-3528	891	17	j.	j.	PROPN
fnp-3528	891	18	;	;	PUNCT
fnp-3528	891	19	cruchaga	cruchaga	NOUN
fnp-3528	891	20	,	,	PUNCT
fnp-3528	891	21	c.	c.	PROPN
fnp-3528	891	22	;	;	PUNCT
fnp-3528	891	23	goate	goate	NOUN
fnp-3528	891	24	,	,	PUNCT
fnp-3528	891	25	a.	a.	NOUN
fnp-3528	891	26	m.	m.	NOUN
fnp-3528	891	27	expression	expression	NOUN
fnp-3528	891	28	of	of	ADP
fnp-3528	891	29	novel	novel	ADJ
fnp-3528	891	30	alzheimer	alzheimer	PROPN
fnp-3528	891	31	's	's	PART
fnp-3528	891	32	disease	disease	NOUN
fnp-3528	891	33	risk	risk	NOUN
fnp-3528	891	34	genes	gene	NOUN
fnp-3528	891	35	in	in	ADP
fnp-3528	891	36	control	control	NOUN
fnp-3528	891	37	and	and	CCONJ
fnp-3528	891	38	alzheimer	alzheimer	PROPN
fnp-3528	891	39	's	's	PART
fnp-3528	891	40	disease	disease	NOUN
fnp-3528	891	41	brains	brain	NOUN
fnp-3528	891	42	.	.	PUNCT
fnp-3528	892	1	plos	plos	PROPN
fnp-3528	892	2	one	one	NUM
fnp-3528	892	3	2012	2012	NUM
fnp-3528	892	4	,	,	PUNCT
fnp-3528	892	5	7	7	NUM
fnp-3528	892	6	,	,	PUNCT
fnp-3528	892	7	e50976	e50976	PROPN
fnp-3528	892	8	.	.	PUNCT
fnp-3528	892	9	allen	allen	PROPN
fnp-3528	892	10	,	,	PUNCT
fnp-3528	892	11	m.	m.	NOUN
fnp-3528	892	12	;	;	PUNCT
fnp-3528	892	13	zou	zou	PROPN
fnp-3528	892	14	,	,	PUNCT
fnp-3528	892	15	f.	f.	PROPN
fnp-3528	892	16	;	;	PUNCT
fnp-3528	892	17	chai	chai	NOUN
fnp-3528	892	18	,	,	PUNCT
fnp-3528	892	19	h.	h.	PROPN
fnp-3528	892	20	s.	s.	PROPN
fnp-3528	892	21	;	;	PUNCT
fnp-3528	892	22	younkin	younkin	NOUN
fnp-3528	892	23	,	,	PUNCT
fnp-3528	892	24	c.	c.	PROPN
fnp-3528	892	25	s.	s.	PROPN
fnp-3528	892	26	;	;	PUNCT
fnp-3528	892	27	crook	crook	NOUN
fnp-3528	892	28	,	,	PUNCT
fnp-3528	892	29	j.	j.	PROPN
fnp-3528	892	30	;	;	PUNCT
fnp-3528	892	31	pankratz	pankratz	NOUN
fnp-3528	892	32	,	,	PUNCT
fnp-3528	892	33	v.	v.	PROPN
fnp-3528	892	34	s.	s.	PROPN
fnp-3528	892	35	;	;	PUNCT
fnp-3528	892	36	carrasquillo	carrasquillo	PROPN
fnp-3528	892	37	,	,	PUNCT
fnp-3528	892	38	m.	m.	NOUN
fnp-3528	892	39	m.	m.	NOUN
fnp-3528	892	40	;	;	PUNCT
fnp-3528	892	41	rowley	rowley	NOUN
fnp-3528	892	42	,	,	PUNCT
fnp-3528	892	43	c.	c.	PROPN
fnp-3528	892	44	n.	n.	PROPN
fnp-3528	892	45	;	;	PUNCT
fnp-3528	892	46	nair	nair	NOUN
fnp-3528	892	47	,	,	PUNCT
fnp-3528	892	48	a.	a.	NOUN
fnp-3528	892	49	a.	a.	PROPN
fnp-3528	892	50	;	;	PUNCT
fnp-3528	892	51	middha	middha	PROPN
fnp-3528	892	52	,	,	PUNCT
fnp-3528	892	53	s.	s.	PROPN
fnp-3528	892	54	;	;	PUNCT
fnp-3528	892	55	maharjan	maharjan	PROPN
fnp-3528	892	56	,	,	PUNCT
fnp-3528	892	57	s.	s.	PROPN
fnp-3528	892	58	;	;	PUNCT
fnp-3528	892	59	nguyen	nguyen	NOUN
fnp-3528	892	60	,	,	PUNCT
fnp-3528	892	61	t.	t.	PROPN
fnp-3528	892	62	;	;	PUNCT
fnp-3528	892	63	ma	ma	PROPN
fnp-3528	892	64	,	,	PUNCT
fnp-3528	892	65	l.	l.	PROPN
fnp-3528	892	66	;	;	PUNCT
fnp-3528	892	67	malphrus	malphrus	PROPN
fnp-3528	892	68	,	,	PUNCT
fnp-3528	892	69	k.	k.	PROPN
fnp-3528	892	70	g.	g.	PROPN
fnp-3528	892	71	;	;	PUNCT
fnp-3528	892	72	palusak	palusak	PROPN
fnp-3528	892	73	,	,	PUNCT
fnp-3528	892	74	r.	r.	PROPN
fnp-3528	892	75	;	;	PUNCT
fnp-3528	892	76	lincoln	lincoln	PROPN
fnp-3528	892	77	,	,	PUNCT
fnp-3528	892	78	s.	s.	PROPN
fnp-3528	892	79	;	;	PUNCT
fnp-3528	892	80	bisceglio	bisceglio	NOUN
fnp-3528	892	81	,	,	PUNCT
fnp-3528	892	82	g.	g.	PROPN
fnp-3528	892	83	;	;	PUNCT
fnp-3528	892	84	georgescu	georgescu	PROPN
fnp-3528	892	85	,	,	PUNCT
fnp-3528	892	86	c.	c.	PROPN
fnp-3528	892	87	;	;	PUNCT
fnp-3528	892	88	schultz	schultz	PROPN
fnp-3528	892	89	,	,	PUNCT
fnp-3528	892	90	d.	d.	PROPN
fnp-3528	892	91	;	;	PUNCT
fnp-3528	892	92	rakhshan	rakhshan	PROPN
fnp-3528	892	93	,	,	PUNCT
fnp-3528	892	94	f.	f.	PROPN
fnp-3528	892	95	;	;	PUNCT
fnp-3528	892	96	kolbert	kolbert	PROPN
fnp-3528	892	97	,	,	PUNCT
fnp-3528	892	98	c.	c.	PROPN
fnp-3528	892	99	p.	p.	PROPN
fnp-3528	892	100	;	;	PUNCT
fnp-3528	893	1	jen	jen	PROPN
fnp-3528	893	2	,	,	PUNCT
fnp-3528	893	3	j.	j.	PROPN
fnp-3528	893	4	;	;	PUNCT
fnp-3528	893	5	haines	haine	NOUN
fnp-3528	893	6	,	,	PUNCT
fnp-3528	893	7	j.	j.	PROPN
fnp-3528	893	8	l.	l.	PROPN
fnp-3528	893	9	;	;	PUNCT
fnp-3528	893	10	mayeux	mayeux	PROPN
fnp-3528	893	11	,	,	PUNCT
fnp-3528	893	12	r.	r.	PROPN
fnp-3528	893	13	;	;	PUNCT
fnp-3528	893	14	pericak	pericak	ADJ
fnp-3528	893	15	-	-	PUNCT
fnp-3528	893	16	vance	vance	NOUN
fnp-3528	893	17	,	,	PUNCT
fnp-3528	893	18	m.	m.	NOUN
fnp-3528	893	19	a.	a.	PROPN
fnp-3528	893	20	;	;	PUNCT
fnp-3528	893	21	farrer	farrer	PROPN
fnp-3528	893	22	,	,	PUNCT
fnp-3528	893	23	l.	l.	PROPN
fnp-3528	893	24	a.	a.	PROPN
fnp-3528	893	25	;	;	PUNCT
fnp-3528	893	26	schellenberg	schellenberg	PROPN
fnp-3528	893	27	,	,	PUNCT
fnp-3528	893	28	g.	g.	PROPN
fnp-3528	893	29	d.	d.	PROPN
fnp-3528	893	30	;	;	PUNCT
fnp-3528	893	31	petersen	petersen	PROPN
fnp-3528	893	32	,	,	PUNCT
fnp-3528	893	33	r.	r.	PROPN
fnp-3528	893	34	c.	c.	PROPN
fnp-3528	893	35	;	;	PUNCT
fnp-3528	893	36	graff	graff	NOUN
fnp-3528	893	37	-	-	PUNCT
fnp-3528	893	38	radford	radford	PROPN
fnp-3528	893	39	,	,	PUNCT
fnp-3528	893	40	n.	n.	PROPN
fnp-3528	893	41	r.	r.	PROPN
fnp-3528	893	42	;	;	PUNCT
fnp-3528	893	43	dickson	dickson	PROPN
fnp-3528	893	44	,	,	PUNCT
fnp-3528	893	45	d.	d.	PROPN
fnp-3528	893	46	w.	w.	PROPN
fnp-3528	893	47	;	;	PUNCT
fnp-3528	893	48	younkin	younkin	PROPN
fnp-3528	893	49	,	,	PUNCT
fnp-3528	893	50	s.	s.	PROPN
fnp-3528	893	51	g.	g.	PROPN
fnp-3528	893	52	;	;	PUNCT
fnp-3528	893	53	ertekin	ertekin	PROPN
fnp-3528	893	54	-	-	PUNCT
fnp-3528	893	55	taner	taner	PROPN
fnp-3528	893	56	,	,	PUNCT
fnp-3528	893	57	n.	n.	NOUN
fnp-3528	893	58	;	;	PUNCT
fnp-3528	893	59	alzheimer	alzheimer	PROPN
fnp-3528	893	60	's	's	PART
fnp-3528	893	61	disease	disease	NOUN
fnp-3528	893	62	genetics	genetic	NOUN
fnp-3528	893	63	,	,	PUNCT
fnp-3528	893	64	c.	c.	PROPN
fnp-3528	893	65	;	;	PUNCT
fnp-3528	893	66	apostolova	apostolova	PROPN
fnp-3528	893	67	,	,	PUNCT
fnp-3528	893	68	l.	l.	PROPN
fnp-3528	893	69	g.	g.	PROPN
fnp-3528	893	70	;	;	PUNCT
fnp-3528	893	71	arnold	arnold	PROPN
fnp-3528	893	72	,	,	PUNCT
fnp-3528	893	73	s.	s.	PROPN
fnp-3528	893	74	e.	e.	PROPN
fnp-3528	893	75	;	;	PUNCT
fnp-3528	893	76	baldwin	baldwin	PROPN
fnp-3528	893	77	,	,	PUNCT
fnp-3528	893	78	c.	c.	PROPN
fnp-3528	893	79	t.	t.	PROPN
fnp-3528	893	80	;	;	PUNCT
fnp-3528	893	81	barber	barber	PROPN
fnp-3528	893	82	,	,	PUNCT
fnp-3528	893	83	r.	r.	PROPN
fnp-3528	893	84	;	;	PUNCT
fnp-3528	893	85	barmada	barmada	NOUN
fnp-3528	893	86	,	,	PUNCT
fnp-3528	893	87	m.	m.	NOUN
fnp-3528	893	88	m.	m.	NOUN
fnp-3528	893	89	;	;	PUNCT
fnp-3528	893	90	beach	beach	NOUN
fnp-3528	893	91	,	,	PUNCT
fnp-3528	893	92	t.	t.	PROPN
fnp-3528	893	93	;	;	PUNCT
fnp-3528	893	94	beecham	beecham	PROPN
fnp-3528	893	95	,	,	PUNCT
fnp-3528	893	96	g.	g.	PROPN
fnp-3528	893	97	w.	w.	PROPN
fnp-3528	893	98	;	;	PUNCT
fnp-3528	893	99	beekly	beekly	PROPN
fnp-3528	893	100	,	,	PUNCT
fnp-3528	893	101	d.	d.	PROPN
fnp-3528	893	102	;	;	PUNCT
fnp-3528	893	103	bennett	bennett	PROPN
fnp-3528	893	104	,	,	PUNCT
fnp-3528	893	105	d.	d.	PROPN
fnp-3528	893	106	a.	a.	PROPN
fnp-3528	893	107	;	;	PUNCT
fnp-3528	893	108	bigio	bigio	NOUN
fnp-3528	893	109	,	,	PUNCT
fnp-3528	893	110	e.	e.	PROPN
fnp-3528	893	111	h.	h.	PROPN
fnp-3528	893	112	;	;	PUNCT
fnp-3528	893	113	bird	bird	NOUN
fnp-3528	893	114	,	,	PUNCT
fnp-3528	893	115	t.	t.	PROPN
fnp-3528	893	116	d.	d.	PROPN
fnp-3528	893	117	;	;	PUNCT
fnp-3528	893	118	blacker	black	ADJ
fnp-3528	893	119	,	,	PUNCT
fnp-3528	893	120	d.	d.	PROPN
fnp-3528	893	121	;	;	PUNCT
fnp-3528	893	122	boeve	boeve	PROPN
fnp-3528	893	123	,	,	PUNCT
fnp-3528	893	124	b.	b.	PROPN
fnp-3528	893	125	f.	f.	PROPN
fnp-3528	893	126	;	;	PUNCT
fnp-3528	893	127	bowen	bowen	PROPN
fnp-3528	893	128	,	,	PUNCT
fnp-3528	893	129	j.	j.	PROPN
fnp-3528	893	130	d.	d.	PROPN
fnp-3528	893	131	;	;	PUNCT
fnp-3528	893	132	boxer	boxer	PROPN
fnp-3528	893	133	,	,	PUNCT
fnp-3528	893	134	a.	a.	NOUN
fnp-3528	893	135	;	;	PUNCT
fnp-3528	893	136	burke	burke	PROPN
fnp-3528	893	137	,	,	PUNCT
fnp-3528	893	138	j.	j.	PROPN
fnp-3528	893	139	r.	r.	PROPN
fnp-3528	893	140	;	;	PUNCT
fnp-3528	893	141	buros	buros	PROPN
fnp-3528	893	142	,	,	PUNCT
fnp-3528	893	143	j.	j.	PROPN
fnp-3528	893	144	;	;	PUNCT
fnp-3528	893	145	buxbaum	buxbaum	PROPN
fnp-3528	893	146	,	,	PUNCT
fnp-3528	893	147	j.	j.	PROPN
fnp-3528	893	148	d.	d.	PROPN
fnp-3528	893	149	;	;	PUNCT
fnp-3528	893	150	cairns	cairns	PROPN
fnp-3528	893	151	,	,	PUNCT
fnp-3528	893	152	n.	n.	PROPN
fnp-3528	893	153	j.	j.	PROPN
fnp-3528	893	154	;	;	PUNCT
fnp-3528	893	155	cantwell	cantwell	PROPN
fnp-3528	893	156	,	,	PUNCT
fnp-3528	893	157	l.	l.	PROPN
fnp-3528	893	158	b.	b.	PROPN
fnp-3528	893	159	;	;	PUNCT
fnp-3528	893	160	cao	cao	PROPN
fnp-3528	893	161	,	,	PUNCT
fnp-3528	893	162	c.	c.	PROPN
fnp-3528	893	163	;	;	PUNCT
fnp-3528	893	164	carlson	carlson	PROPN
fnp-3528	893	165	,	,	PUNCT
fnp-3528	893	166	c.	c.	PROPN
fnp-3528	893	167	s.	s.	PROPN
fnp-3528	893	168	;	;	PUNCT
fnp-3528	893	169	carney	carney	PROPN
fnp-3528	893	170	,	,	PUNCT
fnp-3528	893	171	r.	r.	PROPN
fnp-3528	893	172	m.	m.	PROPN
fnp-3528	893	173	;	;	PUNCT
fnp-3528	893	174	carroll	carroll	PROPN
fnp-3528	893	175	,	,	PUNCT
fnp-3528	893	176	s.	s.	PROPN
fnp-3528	893	177	l.	l.	PROPN
fnp-3528	893	178	;	;	PUNCT
fnp-3528	893	179	chui	chui	PROPN
fnp-3528	893	180	,	,	PUNCT
fnp-3528	893	181	h.	h.	PROPN
fnp-3528	893	182	c.	c.	PROPN
fnp-3528	893	183	;	;	PUNCT
fnp-3528	893	184	clark	clark	PROPN
fnp-3528	893	185	,	,	PUNCT
fnp-3528	893	186	d.	d.	PROPN
fnp-3528	893	187	g.	g.	PROPN
fnp-3528	893	188	;	;	PUNCT
fnp-3528	893	189	corneveaux	corneveaux	PROPN
fnp-3528	893	190	,	,	PUNCT
fnp-3528	893	191	j.	j.	PROPN
fnp-3528	893	192	;	;	PUNCT
fnp-3528	893	193	cotman	cotman	NOUN
fnp-3528	893	194	,	,	PUNCT
fnp-3528	893	195	c.	c.	PROPN
fnp-3528	893	196	w.	w.	PROPN
fnp-3528	893	197	;	;	PUNCT
fnp-3528	893	198	crane	crane	NOUN
fnp-3528	893	199	,	,	PUNCT
fnp-3528	893	200	p.	p.	PROPN
fnp-3528	893	201	k.	k.	PROPN
fnp-3528	893	202	;	;	PUNCT
fnp-3528	894	1	cruchaga	cruchaga	NOUN
fnp-3528	894	2	,	,	PUNCT
fnp-3528	894	3	c.	c.	PROPN
fnp-3528	894	4	;	;	PUNCT
fnp-3528	894	5	cummings	cummings	PROPN
fnp-3528	894	6	,	,	PUNCT
fnp-3528	894	7	j.	j.	PROPN
fnp-3528	894	8	l.	l.	PROPN
fnp-3528	894	9	;	;	PUNCT
fnp-3528	894	10	de	de	X
fnp-3528	894	11	jager	jager	PROPN
fnp-3528	894	12	,	,	PUNCT
fnp-3528	894	13	p.	p.	PROPN
fnp-3528	894	14	l.	l.	PROPN
fnp-3528	894	15	;	;	PUNCT
fnp-3528	894	16	decarli	decarli	PROPN
fnp-3528	894	17	,	,	PUNCT
fnp-3528	894	18	c.	c.	NOUN
fnp-3528	894	19	;	;	PUNCT
fnp-3528	894	20	dekosky	dekosky	PROPN
fnp-3528	894	21	,	,	PUNCT
fnp-3528	894	22	s.	s.	PROPN
fnp-3528	894	23	t.	t.	PROPN
fnp-3528	894	24	;	;	PUNCT
fnp-3528	894	25	demirci	demirci	PROPN
fnp-3528	894	26	,	,	PUNCT
fnp-3528	894	27	f.	f.	PROPN
fnp-3528	894	28	y.	y.	PROPN
fnp-3528	894	29	;	;	PUNCT
fnp-3528	894	30	diaz	diaz	PROPN
fnp-3528	894	31	-	-	PUNCT
fnp-3528	894	32	arrastia	arrastia	PROPN
fnp-3528	894	33	,	,	PUNCT
fnp-3528	894	34	r.	r.	PROPN
fnp-3528	894	35	;	;	PUNCT
fnp-3528	894	36	dick	dick	PROPN
fnp-3528	894	37	,	,	PUNCT
fnp-3528	894	38	m.	m.	NOUN
fnp-3528	894	39	;	;	PUNCT
fnp-3528	894	40	dombroski	dombroski	PROPN
fnp-3528	894	41	,	,	PUNCT
fnp-3528	894	42	b.	b.	PROPN
fnp-3528	894	43	a.	a.	PROPN
fnp-3528	894	44	;	;	PUNCT
fnp-3528	894	45	duara	duara	PROPN
fnp-3528	894	46	,	,	PUNCT
fnp-3528	894	47	r.	r.	PROPN
fnp-3528	894	48	;	;	PUNCT
fnp-3528	894	49	ellis	ellis	PROPN
fnp-3528	894	50	,	,	PUNCT
fnp-3528	894	51	w.	w.	PROPN
fnp-3528	894	52	d.	d.	PROPN
fnp-3528	894	53	;	;	PUNCT
fnp-3528	894	54	evans	evans	PROPN
fnp-3528	894	55	,	,	PUNCT
fnp-3528	894	56	d.	d.	PROPN
fnp-3528	894	57	;	;	PUNCT
fnp-3528	894	58	faber	faber	PROPN
fnp-3528	894	59	,	,	PUNCT
fnp-3528	894	60	k.	k.	PROPN
fnp-3528	894	61	m.	m.	PROPN
fnp-3528	894	62	;	;	PUNCT
fnp-3528	894	63	fallon	fallon	PROPN
fnp-3528	894	64	,	,	PUNCT
fnp-3528	894	65	k.	k.	PROPN
fnp-3528	894	66	b.	b.	PROPN
fnp-3528	894	67	;	;	PUNCT
fnp-3528	894	68	farlow	farlow	ADJ
fnp-3528	894	69	,	,	PUNCT
fnp-3528	894	70	m.	m.	NOUN
fnp-3528	894	71	r.	r.	PROPN
fnp-3528	894	72	;	;	PUNCT
fnp-3528	894	73	ferris	ferris	PROPN
fnp-3528	894	74	,	,	PUNCT
fnp-3528	894	75	s.	s.	PROPN
fnp-3528	894	76	;	;	PUNCT
fnp-3528	894	77	foroud	foroud	ADJ
fnp-3528	894	78	,	,	PUNCT
fnp-3528	894	79	t.	t.	NOUN
fnp-3528	894	80	m.	m.	NOUN
fnp-3528	894	81	;	;	PUNCT
fnp-3528	894	82	frosch	frosch	PROPN
fnp-3528	894	83	,	,	PUNCT
fnp-3528	894	84	m.	m.	NOUN
fnp-3528	894	85	;	;	PUNCT
fnp-3528	894	86	galasko	galasko	PROPN
fnp-3528	894	87	,	,	PUNCT
fnp-3528	894	88	d.	d.	PROPN
fnp-3528	894	89	r.	r.	PROPN
fnp-3528	894	90	;	;	PUNCT
fnp-3528	894	91	gallins	gallin	NOUN
fnp-3528	894	92	,	,	PUNCT
fnp-3528	894	93	p.	p.	PROPN
fnp-3528	894	94	j.	j.	PROPN
fnp-3528	894	95	;	;	PUNCT
fnp-3528	894	96	ganguli	ganguli	PROPN
fnp-3528	894	97	,	,	PUNCT
fnp-3528	894	98	m.	m.	NOUN
fnp-3528	894	99	;	;	PUNCT
fnp-3528	894	100	gearing	gearing	NOUN
fnp-3528	894	101	,	,	PUNCT
fnp-3528	894	102	m.	m.	NOUN
fnp-3528	894	103	;	;	PUNCT
fnp-3528	894	104	geschwind	geschwind	NOUN
fnp-3528	894	105	,	,	PUNCT
fnp-3528	894	106	d.	d.	PROPN
fnp-3528	894	107	h.	h.	PROPN
fnp-3528	894	108	;	;	PUNCT
fnp-3528	894	109	ghetti	ghetti	PROPN
fnp-3528	894	110	,	,	PUNCT
fnp-3528	894	111	b.	b.	PROPN
fnp-3528	894	112	;	;	PUNCT
fnp-3528	894	113	gilbert	gilbert	PROPN
fnp-3528	894	114	,	,	PUNCT
fnp-3528	894	115	j.	j.	PROPN
fnp-3528	894	116	r.	r.	PROPN
fnp-3528	894	117	;	;	PUNCT
fnp-3528	894	118	gilman	gilman	PROPN
fnp-3528	894	119	,	,	PUNCT
fnp-3528	894	120	s.	s.	PROPN
fnp-3528	894	121	;	;	PUNCT
fnp-3528	894	122	giordani	giordani	PROPN
fnp-3528	894	123	,	,	PUNCT
fnp-3528	894	124	b.	b.	PROPN
fnp-3528	894	125	;	;	PUNCT
fnp-3528	894	126	glass	glass	NOUN
fnp-3528	894	127	,	,	PUNCT
fnp-3528	894	128	j.	j.	PROPN
fnp-3528	894	129	d.	d.	PROPN
fnp-3528	894	130	;	;	PUNCT
fnp-3528	894	131	goate	goate	NOUN
fnp-3528	894	132	,	,	PUNCT
fnp-3528	894	133	a.	a.	NOUN
fnp-3528	894	134	m.	m.	NOUN
fnp-3528	894	135	;	;	PUNCT
fnp-3528	894	136	green	green	PROPN
fnp-3528	894	137	,	,	PUNCT
fnp-3528	894	138	r.	r.	PROPN
fnp-3528	894	139	c.	c.	PROPN
fnp-3528	894	140	;	;	PUNCT
fnp-3528	894	141	growdon	growdon	PROPN
fnp-3528	894	142	,	,	PUNCT
fnp-3528	894	143	j.	j.	PROPN
fnp-3528	894	144	h.	h.	PROPN
fnp-3528	894	145	;	;	PUNCT
fnp-3528	894	146	hakonarson	hakonarson	PROPN
fnp-3528	894	147	,	,	PUNCT
fnp-3528	894	148	h.	h.	PROPN
fnp-3528	894	149	;	;	PUNCT
fnp-3528	894	150	hamilton	hamilton	PROPN
fnp-3528	894	151	,	,	PUNCT
fnp-3528	894	152	r.	r.	PROPN
fnp-3528	894	153	l.	l.	PROPN
fnp-3528	894	154	;	;	PUNCT
fnp-3528	894	155	hardy	hardy	ADJ
fnp-3528	894	156	,	,	PUNCT
fnp-3528	894	157	j.	j.	PROPN
fnp-3528	894	158	;	;	PUNCT
fnp-3528	894	159	harrell	harrell	PROPN
fnp-3528	894	160	,	,	PUNCT
fnp-3528	894	161	l.	l.	PROPN
fnp-3528	894	162	e.	e.	PROPN
fnp-3528	894	163	;	;	PUNCT
fnp-3528	894	164	head	head	PROPN
fnp-3528	894	165	,	,	PUNCT
fnp-3528	894	166	e.	e.	PROPN
fnp-3528	894	167	;	;	PUNCT
fnp-3528	894	168	honig	honig	PROPN
fnp-3528	894	169	,	,	PUNCT
fnp-3528	894	170	l.	l.	PROPN
fnp-3528	894	171	s.	s.	PROPN
fnp-3528	894	172	;	;	PUNCT
fnp-3528	894	173	huentelman	huentelman	NOUN
fnp-3528	894	174	,	,	PUNCT
fnp-3528	894	175	m.	m.	NOUN
fnp-3528	894	176	j.	j.	PROPN
fnp-3528	894	177	;	;	PUNCT
fnp-3528	894	178	hulette	hulette	PROPN
fnp-3528	894	179	,	,	PUNCT
fnp-3528	894	180	c.	c.	PROPN
fnp-3528	894	181	m.	m.	NOUN
fnp-3528	894	182	;	;	PUNCT
fnp-3528	894	183	hyman	hyman	PROPN
fnp-3528	894	184	,	,	PUNCT
fnp-3528	894	185	b.	b.	PROPN
fnp-3528	894	186	t.	t.	PROPN
fnp-3528	894	187	;	;	PUNCT
fnp-3528	894	188	jarvik	jarvik	PROPN
fnp-3528	894	189	,	,	PUNCT
fnp-3528	894	190	g.	g.	PROPN
fnp-3528	894	191	p.	p.	PROPN
fnp-3528	894	192	;	;	PUNCT
fnp-3528	894	193	jicha	jicha	PROPN
fnp-3528	894	194	,	,	PUNCT
fnp-3528	894	195	g.	g.	PROPN
fnp-3528	894	196	a.	a.	PROPN
fnp-3528	894	197	;	;	PUNCT
fnp-3528	894	198	jin	jin	PROPN
fnp-3528	894	199	,	,	PUNCT
fnp-3528	894	200	l.	l.	PROPN
fnp-3528	894	201	w.	w.	PROPN
fnp-3528	894	202	;	;	PUNCT
fnp-3528	894	203	jun	jun	PROPN
fnp-3528	894	204	,	,	PUNCT
fnp-3528	894	205	g.	g.	PROPN
fnp-3528	894	206	;	;	PUNCT
fnp-3528	894	207	kamboh	kamboh	PROPN
fnp-3528	894	208	,	,	PUNCT
fnp-3528	894	209	m.	m.	NOUN
fnp-3528	894	210	i.	i.	PROPN
fnp-3528	894	211	;	;	PUNCT
fnp-3528	894	212	karlawish	karlawish	PROPN
fnp-3528	894	213	,	,	PUNCT
fnp-3528	894	214	j.	j.	PROPN
fnp-3528	894	215	;	;	PUNCT
fnp-3528	894	216	karydas	karydas	PROPN
fnp-3528	894	217	,	,	PUNCT
fnp-3528	894	218	a.	a.	NOUN
fnp-3528	894	219	;	;	PUNCT
fnp-3528	894	220	kauwe	kauwe	PROPN
fnp-3528	894	221	,	,	PUNCT
fnp-3528	894	222	j.	j.	PROPN
fnp-3528	894	223	s.	s.	PROPN
fnp-3528	894	224	;	;	PUNCT
fnp-3528	894	225	kaye	kaye	PROPN
fnp-3528	894	226	,	,	PUNCT
fnp-3528	894	227	j.	j.	PROPN
fnp-3528	894	228	a.	a.	PROPN
fnp-3528	894	229	;	;	PUNCT
fnp-3528	894	230	kennedy	kennedy	PROPN
fnp-3528	894	231	,	,	PUNCT
fnp-3528	894	232	n.	n.	PROPN
fnp-3528	894	233	;	;	PUNCT
fnp-3528	894	234	kim	kim	PROPN
fnp-3528	894	235	,	,	PUNCT
fnp-3528	894	236	r.	r.	PROPN
fnp-3528	894	237	;	;	PUNCT
fnp-3528	894	238	koo	koo	PROPN
fnp-3528	894	239	,	,	PUNCT
fnp-3528	894	240	e.	e.	PROPN
fnp-3528	894	241	h.	h.	PROPN
fnp-3528	894	242	;	;	PUNCT
fnp-3528	894	243	kowall	kowall	PROPN
fnp-3528	894	244	,	,	PUNCT
fnp-3528	894	245	n.	n.	PROPN
fnp-3528	894	246	w.	w.	PROPN
fnp-3528	894	247	;	;	PUNCT
fnp-3528	894	248	kramer	kramer	PROPN
fnp-3528	894	249	,	,	PUNCT
fnp-3528	894	250	p.	p.	PROPN
fnp-3528	894	251	;	;	PUNCT
fnp-3528	894	252	kukull	kukull	PROPN
fnp-3528	894	253	,	,	PUNCT
fnp-3528	894	254	w.	w.	PROPN
fnp-3528	894	255	a.	a.	PROPN
fnp-3528	894	256	;	;	PUNCT
fnp-3528	894	257	lah	lah	PROPN
fnp-3528	894	258	,	,	PUNCT
fnp-3528	894	259	j.	j.	PROPN
fnp-3528	894	260	j.	j.	PROPN
fnp-3528	894	261	;	;	PUNCT
fnp-3528	894	262	larson	larson	PROPN
fnp-3528	894	263	,	,	PUNCT
fnp-3528	894	264	e.	e.	PROPN
fnp-3528	894	265	b.	b.	PROPN
fnp-3528	894	266	;	;	PUNCT
fnp-3528	894	267	levey	levey	PROPN
fnp-3528	894	268	,	,	PUNCT
fnp-3528	894	269	a.	a.	NOUN
fnp-3528	894	270	i.	i.	PROPN
fnp-3528	894	271	;	;	PUNCT
fnp-3528	894	272	lieberman	lieberman	PROPN
fnp-3528	894	273	,	,	PUNCT
fnp-3528	894	274	a.	a.	NOUN
fnp-3528	894	275	p.	p.	NOUN
fnp-3528	894	276	;	;	PUNCT
fnp-3528	894	277	lopez	lopez	NOUN
fnp-3528	894	278	,	,	PUNCT
fnp-3528	894	279	o.	o.	PROPN
fnp-3528	894	280	l.	l.	PROPN
fnp-3528	894	281	;	;	PUNCT
fnp-3528	894	282	lunetta	lunetta	PROPN
fnp-3528	894	283	,	,	PUNCT
fnp-3528	894	284	k.	k.	PROPN
fnp-3528	894	285	l.	l.	PROPN
fnp-3528	894	286	;	;	PUNCT
fnp-3528	894	287	mack	mack	PROPN
fnp-3528	894	288	,	,	PUNCT
fnp-3528	894	289	w.	w.	PROPN
fnp-3528	894	290	j.	j.	PROPN
fnp-3528	894	291	;	;	PUNCT
fnp-3528	894	292	marson	marson	PROPN
fnp-3528	894	293	,	,	PUNCT
fnp-3528	894	294	d.	d.	PROPN
fnp-3528	894	295	c.	c.	PROPN
fnp-3528	894	296	;	;	PUNCT
fnp-3528	894	297	martin	martin	PROPN
fnp-3528	894	298	,	,	PUNCT
fnp-3528	894	299	e.	e.	PROPN
fnp-3528	894	300	r.	r.	PROPN
fnp-3528	894	301	;	;	PUNCT
fnp-3528	894	302	martiniuk	martiniuk	NOUN
fnp-3528	894	303	,	,	PUNCT
fnp-3528	894	304	f.	f.	PROPN
fnp-3528	894	305	;	;	PUNCT
fnp-3528	894	306	mash	mash	NOUN
fnp-3528	894	307	,	,	PUNCT
fnp-3528	894	308	d.	d.	PROPN
fnp-3528	894	309	c.	c.	PROPN
fnp-3528	894	310	;	;	PUNCT
fnp-3528	894	311	masliah	masliah	PROPN
fnp-3528	894	312	,	,	PUNCT
fnp-3528	894	313	e.	e.	PROPN
fnp-3528	894	314	;	;	PUNCT
fnp-3528	894	315	mccormick	mccormick	PROPN
fnp-3528	894	316	,	,	PUNCT
fnp-3528	894	317	w.	w.	PROPN
fnp-3528	894	318	c.	c.	PROPN
fnp-3528	894	319	;	;	PUNCT
fnp-3528	894	320	mccurry	mccurry	PROPN
fnp-3528	894	321	,	,	PUNCT
fnp-3528	894	322	s.	s.	PROPN
fnp-3528	894	323	m.	m.	PROPN
fnp-3528	894	324	;	;	PUNCT
fnp-3528	894	325	mcdavid	mcdavid	PROPN
fnp-3528	894	326	,	,	PUNCT
fnp-3528	894	327	a.	a.	NOUN
fnp-3528	894	328	n.	n.	PROPN
fnp-3528	894	329	;	;	PUNCT
fnp-3528	894	330	mckee	mckee	PROPN
fnp-3528	894	331	,	,	PUNCT
fnp-3528	894	332	a.	a.	PROPN
fnp-3528	894	333	c.	c.	PROPN
fnp-3528	894	334	;	;	PUNCT
fnp-3528	894	335	mesulam	mesulam	PROPN
fnp-3528	894	336	,	,	PUNCT
fnp-3528	894	337	m.	m.	NOUN
fnp-3528	894	338	;	;	PUNCT
fnp-3528	894	339	miller	miller	PROPN
fnp-3528	894	340	,	,	PUNCT
fnp-3528	894	341	b.	b.	PROPN
fnp-3528	894	342	l.	l.	PROPN
fnp-3528	894	343	;	;	PUNCT
fnp-3528	894	344	miller	miller	PROPN
fnp-3528	894	345	,	,	PUNCT
fnp-3528	894	346	c.	c.	PROPN
fnp-3528	894	347	a.	a.	PROPN
fnp-3528	894	348	;	;	PUNCT
fnp-3528	894	349	miller	miller	PROPN
fnp-3528	894	350	,	,	PUNCT
fnp-3528	894	351	j.	j.	PROPN
fnp-3528	894	352	w.	w.	PROPN
fnp-3528	894	353	;	;	PUNCT
fnp-3528	894	354	montine	montine	NOUN
fnp-3528	894	355	,	,	PUNCT
fnp-3528	894	356	t.	t.	PROPN
fnp-3528	894	357	j.	j.	PROPN
fnp-3528	894	358	;	;	PUNCT
fnp-3528	894	359	morris	morris	PROPN
fnp-3528	894	360	,	,	PUNCT
fnp-3528	894	361	j.	j.	PROPN
fnp-3528	894	362	c.	c.	PROPN
fnp-3528	894	363	;	;	PUNCT
fnp-3528	894	364	myers	myers	PROPN
fnp-3528	894	365	,	,	PUNCT
fnp-3528	894	366	a.	a.	PROPN
fnp-3528	894	367	j.	j.	PROPN
fnp-3528	894	368	;	;	PUNCT
fnp-3528	894	369	naj	naj	PROPN
fnp-3528	894	370	,	,	PUNCT
fnp-3528	894	371	a.	a.	PROPN
fnp-3528	894	372	c.	c.	PROPN
fnp-3528	894	373	;	;	PUNCT
fnp-3528	894	374	nowotny	nowotny	NOUN
fnp-3528	894	375	,	,	PUNCT
fnp-3528	894	376	p.	p.	PROPN
fnp-3528	894	377	;	;	PUNCT
fnp-3528	894	378	parisi	parisi	PROPN
fnp-3528	894	379	,	,	PUNCT
fnp-3528	894	380	j.	j.	PROPN
fnp-3528	894	381	e.	e.	PROPN
fnp-3528	894	382	;	;	PUNCT
fnp-3528	894	383	perl	perl	PROPN
fnp-3528	894	384	,	,	PUNCT
fnp-3528	894	385	d.	d.	PROPN
fnp-3528	894	386	p.	p.	PROPN
fnp-3528	894	387	;	;	PUNCT
fnp-3528	894	388	peskind	peskind	NOUN
fnp-3528	894	389	,	,	PUNCT
fnp-3528	894	390	e.	e.	PROPN
fnp-3528	894	391	;	;	PUNCT
fnp-3528	894	392	poon	poon	NOUN
fnp-3528	894	393	,	,	PUNCT
fnp-3528	894	394	w.	w.	PROPN
fnp-3528	894	395	w.	w.	PROPN
fnp-3528	894	396	;	;	PUNCT
fnp-3528	894	397	potter	potter	PROPN
fnp-3528	894	398	,	,	PUNCT
fnp-3528	894	399	h.	h.	PROPN
fnp-3528	894	400	;	;	PUNCT
fnp-3528	894	401	quinn	quinn	PROPN
fnp-3528	894	402	,	,	PUNCT
fnp-3528	894	403	j.	j.	PROPN
fnp-3528	894	404	f.	f.	PROPN
fnp-3528	894	405	;	;	PUNCT
fnp-3528	894	406	raj	raj	PROPN
fnp-3528	894	407	,	,	PUNCT
fnp-3528	894	408	a.	a.	NOUN
fnp-3528	894	409	;	;	PUNCT
fnp-3528	894	410	rajbhandary	rajbhandary	PROPN
fnp-3528	894	411	,	,	PUNCT
fnp-3528	894	412	r.	r.	PROPN
fnp-3528	894	413	a.	a.	PROPN
fnp-3528	894	414	;	;	PUNCT
fnp-3528	894	415	raskind	raskind	NOUN
fnp-3528	894	416	,	,	PUNCT
fnp-3528	894	417	m.	m.	NOUN
fnp-3528	894	418	;	;	PUNCT
fnp-3528	894	419	reiman	reiman	NOUN
fnp-3528	894	420	,	,	PUNCT
fnp-3528	894	421	e.	e.	PROPN
fnp-3528	894	422	m.	m.	PROPN
fnp-3528	894	423	;	;	PUNCT
fnp-3528	894	424	reisberg	reisberg	PROPN
fnp-3528	894	425	,	,	PUNCT
fnp-3528	894	426	b.	b.	PROPN
fnp-3528	894	427	;	;	PUNCT
fnp-3528	894	428	reitz	reitz	PROPN
fnp-3528	894	429	,	,	PUNCT
fnp-3528	894	430	c.	c.	PROPN
fnp-3528	894	431	;	;	PUNCT
fnp-3528	894	432	ringman	ringman	NOUN
fnp-3528	894	433	,	,	PUNCT
fnp-3528	894	434	j.	j.	PROPN
fnp-3528	894	435	m.	m.	PROPN
fnp-3528	894	436	;	;	PUNCT
fnp-3528	894	437	roberson	roberson	PROPN
fnp-3528	894	438	,	,	PUNCT
fnp-3528	894	439	e.	e.	PROPN
fnp-3528	894	440	d.	d.	PROPN
fnp-3528	894	441	;	;	PUNCT
fnp-3528	894	442	rogaeva	rogaeva	PROPN
fnp-3528	894	443	,	,	PUNCT
fnp-3528	894	444	e.	e.	PROPN
fnp-3528	894	445	;	;	PUNCT
fnp-3528	894	446	rosenberg	rosenberg	PROPN
fnp-3528	894	447	,	,	PUNCT
fnp-3528	894	448	r.	r.	PROPN
fnp-3528	894	449	n.	n.	PROPN
fnp-3528	894	450	;	;	PUNCT
fnp-3528	894	451	sano	sano	PROPN
fnp-3528	894	452	,	,	PUNCT
fnp-3528	894	453	m.	m.	NOUN
fnp-3528	894	454	;	;	PUNCT
fnp-3528	894	455	saykin	saykin	X
fnp-3528	894	456	,	,	PUNCT
fnp-3528	894	457	a.	a.	PROPN
fnp-3528	894	458	j.	j.	PROPN
fnp-3528	894	459	;	;	PUNCT
fnp-3528	894	460	schneider	schneider	PROPN
fnp-3528	894	461	,	,	PUNCT
fnp-3528	894	462	j.	j.	PROPN
fnp-3528	894	463	a.	a.	PROPN
fnp-3528	894	464	;	;	PUNCT
fnp-3528	894	465	schneider	schneider	PROPN
fnp-3528	894	466	,	,	PUNCT
fnp-3528	894	467	l.	l.	PROPN
fnp-3528	894	468	s.	s.	PROPN
fnp-3528	894	469	;	;	PUNCT
fnp-3528	894	470	seeley	seeley	PROPN
fnp-3528	894	471	,	,	PUNCT
fnp-3528	894	472	w.	w.	PROPN
fnp-3528	894	473	;	;	PUNCT
fnp-3528	894	474	shelanski	shelanski	NOUN
fnp-3528	894	475	,	,	PUNCT
fnp-3528	894	476	m.	m.	NOUN
fnp-3528	894	477	l.	l.	PROPN
fnp-3528	894	478	;	;	PUNCT
fnp-3528	894	479	slifer	slifer	NOUN
fnp-3528	894	480	,	,	PUNCT
fnp-3528	894	481	m.	m.	NOUN
fnp-3528	894	482	a.	a.	PROPN
fnp-3528	894	483	;	;	PUNCT
fnp-3528	894	484	smith	smith	PROPN
fnp-3528	894	485	,	,	PUNCT
fnp-3528	894	486	c.	c.	PROPN
fnp-3528	894	487	d.	d.	PROPN
fnp-3528	894	488	;	;	PUNCT
fnp-3528	894	489	sonnen	sonnen	PROPN
fnp-3528	894	490	,	,	PUNCT
fnp-3528	894	491	j.	j.	PROPN
fnp-3528	894	492	a.	a.	PROPN
fnp-3528	894	493	;	;	PUNCT
fnp-3528	894	494	spina	spina	NOUN
fnp-3528	894	495	,	,	PUNCT
fnp-3528	894	496	s.	s.	PROPN
fnp-3528	894	497	;	;	PUNCT
fnp-3528	894	498	st	st	PROPN
fnp-3528	894	499	george	george	PROPN
fnp-3528	894	500	-	-	PUNCT
fnp-3528	894	501	hyslop	hyslop	PROPN
fnp-3528	894	502	,	,	PUNCT
fnp-3528	894	503	p.	p.	NOUN
fnp-3528	894	504	;	;	PUNCT
fnp-3528	894	505	stern	stern	ADJ
fnp-3528	894	506	,	,	PUNCT
fnp-3528	894	507	r.	r.	PROPN
fnp-3528	894	508	a.	a.	PROPN
fnp-3528	894	509	;	;	PUNCT
fnp-3528	894	510	tanzi	tanzi	PROPN
fnp-3528	894	511	,	,	PUNCT
fnp-3528	894	512	r.	r.	PROPN
fnp-3528	894	513	e.	e.	PROPN
fnp-3528	894	514	;	;	PUNCT
fnp-3528	894	515	trojanowski	trojanowski	PROPN
fnp-3528	894	516	,	,	PUNCT
fnp-3528	894	517	j.	j.	PROPN
fnp-3528	894	518	q.	q.	PROPN
fnp-3528	894	519	;	;	PUNCT
fnp-3528	894	520	troncoso	troncoso	PROPN
fnp-3528	894	521	,	,	PUNCT
fnp-3528	894	522	j.	j.	PROPN
fnp-3528	894	523	c.	c.	PROPN
fnp-3528	894	524	;	;	PUNCT
fnp-3528	894	525	tsuang	tsuang	PROPN
fnp-3528	894	526	,	,	PUNCT
fnp-3528	894	527	d.	d.	PROPN
fnp-3528	894	528	w.	w.	PROPN
fnp-3528	894	529	;	;	PUNCT
fnp-3528	894	530	van	van	PROPN
fnp-3528	894	531	deerlin	deerlin	PROPN
fnp-3528	894	532	,	,	PUNCT
fnp-3528	894	533	v.	v.	ADP
fnp-3528	894	534	m.	m.	NOUN
fnp-3528	894	535	;	;	PUNCT
fnp-3528	894	536	vardarajan	vardarajan	ADJ
fnp-3528	894	537	,	,	PUNCT
fnp-3528	894	538	b.	b.	PROPN
fnp-3528	894	539	n.	n.	PROPN
fnp-3528	894	540	;	;	PUNCT
fnp-3528	894	541	vinters	vinter	NOUN
fnp-3528	894	542	,	,	PUNCT
fnp-3528	894	543	h.	h.	PROPN
fnp-3528	894	544	v.	v.	PROPN
fnp-3528	894	545	;	;	PUNCT
fnp-3528	894	546	vonsattel	vonsattel	PROPN
fnp-3528	894	547	,	,	PUNCT
fnp-3528	894	548	j.	j.	PROPN
fnp-3528	894	549	p.	p.	PROPN
fnp-3528	894	550	;	;	PUNCT
fnp-3528	894	551	wang	wang	PROPN
fnp-3528	894	552	,	,	PUNCT
fnp-3528	894	553	l.	l.	PROPN
fnp-3528	894	554	s.	s.	PROPN
fnp-3528	894	555	;	;	PUNCT
fnp-3528	894	556	weintraub	weintraub	PROPN
fnp-3528	894	557	,	,	PUNCT
fnp-3528	894	558	s.	s.	PROPN
fnp-3528	894	559	;	;	PUNCT
fnp-3528	894	560	welsh	welsh	NOUN
fnp-3528	894	561	-	-	PUNCT
fnp-3528	894	562	bohmer	bohmer	PROPN
fnp-3528	894	563	,	,	PUNCT
fnp-3528	894	564	k.	k.	PROPN
fnp-3528	894	565	a.	a.	PROPN
fnp-3528	894	566	;	;	PUNCT
fnp-3528	894	567	williamson	williamson	PROPN
fnp-3528	894	568	,	,	PUNCT
fnp-3528	894	569	j.	j.	PROPN
fnp-3528	894	570	;	;	PUNCT
fnp-3528	894	571	woltjer	woltjer	PROPN
fnp-3528	894	572	,	,	PUNCT
fnp-3528	894	573	r.	r.	PROPN
fnp-3528	894	574	l.	l.	PROPN
fnp-3528	894	575	novel	novel	PROPN
fnp-3528	894	576	late	late	ADJ
fnp-3528	894	577	-	-	PUNCT
fnp-3528	894	578	onset	onset	NOUN
fnp-3528	894	579	alzheimer	alzheimer	NOUN
fnp-3528	894	580	disease	disease	NOUN
fnp-3528	894	581	loci	loci	NOUN
fnp-3528	894	582	variants	variant	NOUN
fnp-3528	894	583	associate	associate	VERB
fnp-3528	894	584	with	with	ADP
fnp-3528	894	585	brain	brain	NOUN
fnp-3528	894	586	gene	gene	NOUN
fnp-3528	894	587	expression	expression	NOUN
fnp-3528	894	588	.	.	PUNCT
fnp-3528	895	1	neurol	neurol	PROPN
fnp-3528	895	2	2012	2012	NUM
fnp-3528	895	3	,	,	PUNCT
fnp-3528	895	4	79	79	NUM
fnp-3528	895	5	,	,	PUNCT
fnp-3528	895	6	221	221	NUM
fnp-3528	895	7	-	-	SYM
fnp-3528	895	8	8	8	NUM
fnp-3528	895	9	.	.	PUNCT
fnp-3528	896	1	steinberg	steinberg	PROPN
fnp-3528	896	2	,	,	PUNCT
fnp-3528	896	3	s.	s.	PROPN
fnp-3528	896	4	;	;	PUNCT
fnp-3528	896	5	stefansson	stefansson	PROPN
fnp-3528	896	6	,	,	PUNCT
fnp-3528	896	7	h.	h.	PROPN
fnp-3528	896	8	;	;	PUNCT
fnp-3528	896	9	jonsson	jonsson	PROPN
fnp-3528	896	10	,	,	PUNCT
fnp-3528	896	11	t.	t.	PROPN
fnp-3528	896	12	;	;	PUNCT
fnp-3528	896	13	johannsdottir	johannsdottir	PROPN
fnp-3528	896	14	,	,	PUNCT
fnp-3528	896	15	h.	h.	PROPN
fnp-3528	896	16	;	;	PUNCT
fnp-3528	896	17	ingason	ingason	NOUN
fnp-3528	896	18	,	,	PUNCT
fnp-3528	896	19	a.	a.	NOUN
fnp-3528	896	20	;	;	PUNCT
fnp-3528	896	21	helgason	helgason	PROPN
fnp-3528	896	22	,	,	PUNCT
fnp-3528	896	23	h.	h.	PROPN
fnp-3528	896	24	;	;	PUNCT
fnp-3528	896	25	sulem	sulem	PROPN
fnp-3528	896	26	,	,	PUNCT
fnp-3528	896	27	p.	p.	PROPN
fnp-3528	896	28	;	;	PUNCT
fnp-3528	896	29	magnusson	magnusson	PROPN
fnp-3528	896	30	,	,	PUNCT
fnp-3528	896	31	o.	o.	PROPN
fnp-3528	896	32	t.	t.	PROPN
fnp-3528	896	33	;	;	PUNCT
fnp-3528	896	34	gudjonsson	gudjonsson	PROPN
fnp-3528	896	35	,	,	PUNCT
fnp-3528	896	36	s.	s.	PROPN
fnp-3528	896	37	a.	a.	PROPN
fnp-3528	896	38	;	;	PUNCT
fnp-3528	896	39	unnsteinsdottir	unnsteinsdottir	PROPN
fnp-3528	896	40	,	,	PUNCT
fnp-3528	896	41	u.	u.	PROPN
fnp-3528	896	42	;	;	PUNCT
fnp-3528	896	43	kong	kong	PROPN
fnp-3528	896	44	,	,	PUNCT
fnp-3528	896	45	a.	a.	NOUN
fnp-3528	896	46	;	;	PUNCT
fnp-3528	896	47	helisalmi	helisalmi	PROPN
fnp-3528	896	48	,	,	PUNCT
fnp-3528	896	49	s.	s.	PROPN
fnp-3528	896	50	;	;	PUNCT
fnp-3528	896	51	soininen	soininen	PROPN
fnp-3528	896	52	,	,	PUNCT
fnp-3528	896	53	h.	h.	PROPN
fnp-3528	896	54	;	;	PUNCT
fnp-3528	896	55	lah	lah	PROPN
fnp-3528	896	56	,	,	PUNCT
fnp-3528	896	57	j.	j.	PROPN
fnp-3528	896	58	j.	j.	PROPN
fnp-3528	896	59	;	;	PUNCT
fnp-3528	896	60	demgene	demgene	PROPN
fnp-3528	896	61	;	;	PUNCT
fnp-3528	896	62	aarsland	aarsland	ADJ
fnp-3528	896	63	,	,	PUNCT
fnp-3528	896	64	d.	d.	PROPN
fnp-3528	896	65	;	;	PUNCT
fnp-3528	896	66	fladby	fladby	NOUN
fnp-3528	896	67	,	,	PUNCT
fnp-3528	896	68	t.	t.	PROPN
fnp-3528	896	69	;	;	PUNCT
fnp-3528	896	70	ulstein	ulstein	PROPN
fnp-3528	896	71	,	,	PUNCT
fnp-3528	896	72	i.	i.	PROPN
fnp-3528	896	73	d.	d.	PROPN
fnp-3528	896	74	;	;	PUNCT
fnp-3528	896	75	djurovic	djurovic	PROPN
fnp-3528	896	76	,	,	PUNCT
fnp-3528	896	77	s.	s.	PROPN
fnp-3528	896	78	;	;	PUNCT
fnp-3528	896	79	sando	sando	PROPN
fnp-3528	896	80	,	,	PUNCT
fnp-3528	896	81	s.	s.	PROPN
fnp-3528	896	82	b.	b.	PROPN
fnp-3528	896	83	;	;	PUNCT
fnp-3528	896	84	white	white	PROPN
fnp-3528	896	85	,	,	PUNCT
fnp-3528	896	86	l.	l.	PROPN
fnp-3528	896	87	r.	r.	PROPN
fnp-3528	896	88	;	;	PUNCT
fnp-3528	896	89	knudsen	knudsen	PROPN
fnp-3528	896	90	,	,	PUNCT
fnp-3528	896	91	g.	g.	PROPN
fnp-3528	896	92	p.	p.	PROPN
fnp-3528	896	93	;	;	PUNCT
fnp-3528	896	94	westlye	westlye	NOUN
fnp-3528	896	95	,	,	PUNCT
fnp-3528	896	96	l.	l.	PROPN
fnp-3528	896	97	t.	t.	PROPN
fnp-3528	896	98	;	;	PUNCT
fnp-3528	896	99	selbaek	selbaek	PROPN
fnp-3528	896	100	,	,	PUNCT
fnp-3528	896	101	g.	g.	PROPN
fnp-3528	896	102	;	;	PUNCT
fnp-3528	896	103	giegling	giegling	NOUN
fnp-3528	896	104	,	,	PUNCT
fnp-3528	896	105	i.	i.	NOUN
fnp-3528	896	106	;	;	PUNCT
fnp-3528	896	107	hampel	hampel	PROPN
fnp-3528	896	108	,	,	PUNCT
fnp-3528	896	109	h.	h.	PROPN
fnp-3528	896	110	;	;	PUNCT
fnp-3528	896	111	hiltunen	hiltunen	PROPN
fnp-3528	896	112	,	,	PUNCT
fnp-3528	896	113	m.	m.	NOUN
fnp-3528	896	114	;	;	PUNCT
fnp-3528	896	115	levey	levey	PROPN
fnp-3528	896	116	,	,	PUNCT
fnp-3528	896	117	a.	a.	NOUN
fnp-3528	896	118	i.	i.	PROPN
fnp-3528	896	119	;	;	PUNCT
fnp-3528	896	120	andreassen	andreassen	PROPN
fnp-3528	896	121	,	,	PUNCT
fnp-3528	896	122	o.	o.	NOUN
fnp-3528	896	123	a.	a.	PROPN
fnp-3528	896	124	;	;	PUNCT
fnp-3528	896	125	rujescu	rujescu	NOUN
fnp-3528	896	126	,	,	PUNCT
fnp-3528	896	127	d.	d.	PROPN
fnp-3528	896	128	;	;	PUNCT
fnp-3528	896	129	jonsson	jonsson	PROPN
fnp-3528	896	130	,	,	PUNCT
fnp-3528	896	131	p.	p.	PROPN
fnp-3528	896	132	v.	v.	PROPN
fnp-3528	896	133	;	;	PUNCT
fnp-3528	896	134	bjornsson	bjornsson	PROPN
fnp-3528	896	135	,	,	PUNCT
fnp-3528	896	136	s.	s.	PROPN
fnp-3528	896	137	;	;	PUNCT
fnp-3528	896	138	snaedal	snaedal	ADJ
fnp-3528	896	139	,	,	PUNCT
fnp-3528	896	140	j.	j.	PROPN
fnp-3528	896	141	;	;	PUNCT
fnp-3528	896	142	stefansson	stefansson	PROPN
fnp-3528	896	143	,	,	PUNCT
fnp-3528	896	144	k.	k.	PROPN
fnp-3528	896	145	loss	loss	PROPN
fnp-3528	896	146	-	-	PUNCT
fnp-3528	896	147	of	of	ADP
fnp-3528	896	148	-	-	PUNCT
fnp-3528	896	149	function	function	NOUN
fnp-3528	896	150	variants	variant	NOUN
fnp-3528	896	151	in	in	ADP
fnp-3528	896	152	abca7	abca7	PROPN
fnp-3528	896	153	confer	confer	NOUN
fnp-3528	896	154	risk	risk	NOUN
fnp-3528	896	155	of	of	ADP
fnp-3528	896	156	alzheimer	alzheimer	PROPN
fnp-3528	896	157	's	's	PART
fnp-3528	896	158	disease	disease	NOUN
fnp-3528	896	159	.	.	PUNCT
fnp-3528	897	1	nat	nat	PROPN
fnp-3528	897	2	genet	genet	PROPN
fnp-3528	897	3	2015	2015	NUM
fnp-3528	897	4	,	,	PUNCT
fnp-3528	897	5	47	47	NUM
fnp-3528	897	6	,	,	PUNCT
fnp-3528	897	7	445	445	NUM
fnp-3528	897	8	-	-	SYM
fnp-3528	897	9	7	7	NUM
fnp-3528	897	10	.	.	PUNCT
fnp-3528	897	11	shulman	shulman	PROPN
fnp-3528	897	12	,	,	PUNCT
fnp-3528	897	13	j.	j.	PROPN
fnp-3528	897	14	m.	m.	PROPN
fnp-3528	897	15	;	;	PUNCT
fnp-3528	897	16	chen	chen	PROPN
fnp-3528	897	17	,	,	PUNCT
fnp-3528	897	18	k.	k.	PROPN
fnp-3528	897	19	;	;	PUNCT
fnp-3528	897	20	keenan	keenan	PROPN
fnp-3528	897	21	,	,	PUNCT
fnp-3528	897	22	b.	b.	PROPN
fnp-3528	897	23	t.	t.	PROPN
fnp-3528	897	24	;	;	PUNCT
fnp-3528	897	25	chibnik	chibnik	PROPN
fnp-3528	897	26	,	,	PUNCT
fnp-3528	897	27	l.	l.	PROPN
fnp-3528	897	28	b.	b.	PROPN
fnp-3528	897	29	;	;	PUNCT
fnp-3528	897	30	fleisher	fleisher	PROPN
fnp-3528	897	31	,	,	PUNCT
fnp-3528	897	32	a.	a.	PROPN
fnp-3528	897	33	;	;	PUNCT
fnp-3528	897	34	thiyyagura	thiyyagura	ADV
fnp-3528	897	35	,	,	PUNCT
fnp-3528	897	36	p.	p.	NOUN
fnp-3528	897	37	;	;	PUNCT
fnp-3528	897	38	roontiva	roontiva	PROPN
fnp-3528	897	39	,	,	PUNCT
fnp-3528	897	40	a.	a.	NOUN
fnp-3528	897	41	;	;	PUNCT
fnp-3528	897	42	mccabe	mccabe	PROPN
fnp-3528	897	43	,	,	PUNCT
fnp-3528	897	44	c.	c.	PROPN
fnp-3528	897	45	;	;	PUNCT
fnp-3528	897	46	patsopoulos	patsopoulo	NOUN
fnp-3528	897	47	,	,	PUNCT
fnp-3528	897	48	n.	n.	PROPN
fnp-3528	897	49	a.	a.	NOUN
fnp-3528	897	50	;	;	PUNCT
fnp-3528	897	51	corneveaux	corneveaux	PROPN
fnp-3528	897	52	,	,	PUNCT
fnp-3528	897	53	j.	j.	PROPN
fnp-3528	897	54	j.	j.	PROPN
fnp-3528	897	55	;	;	PUNCT
fnp-3528	897	56	yu	yu	PROPN
fnp-3528	897	57	,	,	PUNCT
fnp-3528	897	58	l.	l.	PROPN
fnp-3528	897	59	;	;	PUNCT
fnp-3528	897	60	huentelman	huentelman	NOUN
fnp-3528	897	61	,	,	PUNCT
fnp-3528	897	62	m.	m.	NOUN
fnp-3528	897	63	j.	j.	PROPN
fnp-3528	897	64	;	;	PUNCT
fnp-3528	897	65	evans	evans	PROPN
fnp-3528	897	66	,	,	PUNCT
fnp-3528	897	67	d.	d.	PROPN
fnp-3528	897	68	a.	a.	PROPN
fnp-3528	897	69	;	;	PUNCT
fnp-3528	897	70	schneider	schneider	PROPN
fnp-3528	897	71	,	,	PUNCT
fnp-3528	897	72	j.	j.	PROPN
fnp-3528	897	73	a.	a.	PROPN
fnp-3528	897	74	;	;	PUNCT
fnp-3528	897	75	reiman	reiman	NOUN
fnp-3528	897	76	,	,	PUNCT
fnp-3528	897	77	e.	e.	PROPN
fnp-3528	897	78	m.	m.	PROPN
fnp-3528	897	79	;	;	PUNCT
fnp-3528	897	80	de	de	X
fnp-3528	897	81	jager	jager	PROPN
fnp-3528	897	82	,	,	PUNCT
fnp-3528	897	83	p.	p.	PROPN
fnp-3528	897	84	l.	l.	PROPN
fnp-3528	897	85	;	;	PUNCT
fnp-3528	897	86	bennett	bennett	PROPN
fnp-3528	897	87	,	,	PUNCT
fnp-3528	897	88	d.	d.	PROPN
fnp-3528	897	89	a.	a.	PROPN
fnp-3528	897	90	genetic	genetic	ADJ
fnp-3528	897	91	susceptibility	susceptibility	NOUN
fnp-3528	897	92	for	for	ADP
fnp-3528	897	93	alzheimer	alzheimer	PROPN
fnp-3528	897	94	disease	disease	NOUN
fnp-3528	897	95	neuritic	neuritic	ADJ
fnp-3528	897	96	plaque	plaque	NOUN
fnp-3528	897	97	pathology	pathology	NOUN
fnp-3528	897	98	.	.	PUNCT
fnp-3528	898	1	jama	jama	PROPN
fnp-3528	898	2	neurol	neurol	PROPN
fnp-3528	898	3	2013	2013	NUM
fnp-3528	898	4	,	,	PUNCT
fnp-3528	898	5	70	70	NUM
fnp-3528	898	6	,	,	PUNCT
fnp-3528	898	7	1150	1150	NUM
fnp-3528	898	8	-	-	SYM
fnp-3528	898	9	7	7	NUM
fnp-3528	898	10	.	.	PUNCT
fnp-3528	898	11	sinha	sinha	NOUN
fnp-3528	898	12	,	,	PUNCT
fnp-3528	898	13	n.	n.	PROPN
fnp-3528	898	14	;	;	PUNCT
fnp-3528	898	15	berg	berg	PROPN
fnp-3528	898	16	,	,	PUNCT
fnp-3528	898	17	c.	c.	PROPN
fnp-3528	898	18	n.	n.	PROPN
fnp-3528	898	19	;	;	PUNCT
fnp-3528	898	20	shaw	shaw	PROPN
fnp-3528	898	21	,	,	PUNCT
fnp-3528	898	22	a.	a.	NOUN
fnp-3528	898	23	;	;	PUNCT
fnp-3528	898	24	gluck	gluck	NOUN
fnp-3528	898	25	,	,	PUNCT
fnp-3528	898	26	m.	m.	NOUN
fnp-3528	898	27	a.	a.	NOUN
fnp-3528	898	28	abca7	abca7	PROPN
fnp-3528	898	29	genotype	genotype	NOUN
fnp-3528	898	30	moderates	moderate	VERB
fnp-3528	898	31	the	the	DET
fnp-3528	898	32	effect	effect	NOUN
fnp-3528	898	33	of	of	ADP
fnp-3528	898	34	aerobic	aerobic	ADJ
fnp-3528	898	35	exercise	exercise	NOUN
fnp-3528	898	36	intervention	intervention	NOUN
fnp-3528	898	37	on	on	ADP
fnp-3528	898	38	generalization	generalization	NOUN
fnp-3528	898	39	of	of	ADP
fnp-3528	898	40	prior	prior	ADJ
fnp-3528	898	41	learning	learn	VERB
fnp-3528	898	42	in	in	ADP
fnp-3528	898	43	healthy	healthy	ADJ
fnp-3528	898	44	older	old	ADJ
fnp-3528	898	45	african	african	ADJ
fnp-3528	898	46	americans	americans	PROPN
fnp-3528	898	47	.	.	PUNCT
fnp-3528	899	1	j	j	PROPN
fnp-3528	899	2	alzheimers	alzheimers	PROPN
fnp-3528	899	3	dis	dis	PROPN
fnp-3528	899	4	2020	2020	NUM
fnp-3528	899	5	,	,	PUNCT
fnp-3528	899	6	74	74	NUM
fnp-3528	899	7	,	,	PUNCT
fnp-3528	899	8	309	309	NUM
fnp-3528	899	9	-	-	SYM
fnp-3528	899	10	18	18	NUM
fnp-3528	899	11	.	.	PUNCT
fnp-3528	900	1	lamartiniere	lamartiniere	PROPN
fnp-3528	900	2	,	,	PUNCT
fnp-3528	900	3	y.	y.	PROPN
fnp-3528	900	4	;	;	PUNCT
fnp-3528	900	5	boucau	boucau	PROPN
fnp-3528	900	6	,	,	PUNCT
fnp-3528	900	7	m.	m.	PROPN
fnp-3528	900	8	c.	c.	PROPN
fnp-3528	900	9	;	;	PUNCT
fnp-3528	900	10	dehouck	dehouck	PROPN
fnp-3528	900	11	,	,	PUNCT
fnp-3528	900	12	l.	l.	PROPN
fnp-3528	900	13	;	;	PUNCT
fnp-3528	900	14	krohn	krohn	PROPN
fnp-3528	900	15	,	,	PUNCT
fnp-3528	900	16	m.	m.	NOUN
fnp-3528	900	17	;	;	PUNCT
fnp-3528	900	18	pahnke	pahnke	PROPN
fnp-3528	900	19	,	,	PUNCT
fnp-3528	900	20	j.	j.	PROPN
fnp-3528	900	21	;	;	PUNCT
fnp-3528	900	22	candela	candela	PROPN
fnp-3528	900	23	,	,	PUNCT
fnp-3528	900	24	p.	p.	NOUN
fnp-3528	900	25	;	;	PUNCT
fnp-3528	900	26	gosselet	gosselet	NOUN
fnp-3528	900	27	,	,	PUNCT
fnp-3528	900	28	f.	f.	PROPN
fnp-3528	900	29	;	;	PUNCT
fnp-3528	900	30	fenart	fenart	NOUN
fnp-3528	900	31	,	,	PUNCT
fnp-3528	900	32	l.	l.	PROPN
fnp-3528	900	33	abca7	abca7	PROPN
fnp-3528	900	34	downregulation	downregulation	NOUN
fnp-3528	900	35	modifies	modify	VERB
fnp-3528	900	36	cellular	cellular	ADJ
fnp-3528	900	37	cholesterol	cholesterol	NOUN
fnp-3528	900	38	homeostasis	homeostasis	NOUN
fnp-3528	900	39	and	and	CCONJ
fnp-3528	900	40	decreases	decrease	VERB
fnp-3528	900	41	amyloid	amyloid	NOUN
fnp-3528	900	42	-	-	PUNCT
fnp-3528	900	43	beta	beta	NOUN
fnp-3528	900	44	peptide	peptide	NOUN
fnp-3528	900	45	efflux	efflux	VERB
fnp-3528	900	46	in	in	ADP
fnp-3528	900	47	an	an	DET
fnp-3528	900	48	in	in	X
fnp-3528	900	49	vitro	vitro	X
fnp-3528	900	50	model	model	NOUN
fnp-3528	900	51	of	of	ADP
fnp-3528	900	52	the	the	DET
fnp-3528	900	53	blood	blood	NOUN
fnp-3528	900	54	-	-	PUNCT
fnp-3528	900	55	brain	brain	NOUN
fnp-3528	900	56	barrier	barrier	NOUN
fnp-3528	900	57	.	.	PUNCT
fnp-3528	901	1	j	j	PROPN
fnp-3528	901	2	alzheimers	alzheimers	PROPN
fnp-3528	901	3	dis	dis	PROPN
fnp-3528	901	4	2018	2018	NUM
fnp-3528	901	5	,	,	PUNCT
fnp-3528	901	6	64	64	NUM
fnp-3528	901	7	,	,	PUNCT
fnp-3528	901	8	1195	1195	NUM
fnp-3528	901	9	-	-	SYM
fnp-3528	901	10	1211	1211	NUM
fnp-3528	901	11	.	.	PUNCT
fnp-3528	902	1	li	li	PROPN
fnp-3528	902	2	,	,	PUNCT
fnp-3528	902	3	m.	m.	NOUN
fnp-3528	902	4	;	;	PUNCT
fnp-3528	902	5	yuan	yuan	NOUN
fnp-3528	902	6	,	,	PUNCT
fnp-3528	902	7	y.	y.	PROPN
fnp-3528	902	8	;	;	PUNCT
fnp-3528	902	9	hu	hu	PROPN
fnp-3528	902	10	,	,	PUNCT
fnp-3528	902	11	b.	b.	PROPN
fnp-3528	902	12	;	;	PUNCT
fnp-3528	902	13	wu	wu	PROPN
fnp-3528	902	14	,	,	PUNCT
fnp-3528	902	15	l.	l.	PROPN
fnp-3528	902	16	study	study	PROPN
fnp-3528	902	17	on	on	ADP
fnp-3528	902	18	lentivirus	lentivirus	NOUN
fnp-3528	902	19	-	-	PUNCT
fnp-3528	902	20	mediated	mediate	VERB
fnp-3528	902	21	abca7	abca7	NOUN
fnp-3528	902	22	improves	improve	VERB
fnp-3528	902	23	neurocognitive	neurocognitive	ADJ
fnp-3528	902	24	function	function	NOUN
fnp-3528	902	25	and	and	CCONJ
fnp-3528	902	26	related	related	ADJ
fnp-3528	902	27	mechanisms	mechanism	NOUN
fnp-3528	902	28	in	in	ADP
fnp-3528	902	29	the	the	DET
fnp-3528	902	30	c57bl/6	c57bl/6	NOUN
fnp-3528	902	31	mouse	mouse	NOUN
fnp-3528	902	32	model	model	NOUN
fnp-3528	902	33	of	of	ADP
fnp-3528	902	34	alzheimer	alzheimer	PROPN
fnp-3528	902	35	's	's	PART
fnp-3528	902	36	disease	disease	NOUN
fnp-3528	902	37	.	.	PUNCT
fnp-3528	903	1	j	j	PROPN
fnp-3528	903	2	mol	mol	PROPN
fnp-3528	903	3	neurosci	neurosci	PROPN
fnp-3528	903	4	2017	2017	NUM
fnp-3528	903	5	,	,	PUNCT
fnp-3528	903	6	61	61	NUM
fnp-3528	903	7	,	,	PUNCT
fnp-3528	903	8	489	489	NUM
fnp-3528	903	9	-	-	SYM
fnp-3528	903	10	97	97	NUM
fnp-3528	903	11	.	.	PUNCT
fnp-3528	904	1	sakae	sakae	NOUN
fnp-3528	904	2	,	,	PUNCT
fnp-3528	904	3	n.	n.	NOUN
fnp-3528	904	4	;	;	PUNCT
fnp-3528	904	5	liu	liu	PROPN
fnp-3528	904	6	,	,	PUNCT
fnp-3528	904	7	c.	c.	PROPN
fnp-3528	904	8	c.	c.	PROPN
fnp-3528	904	9	;	;	PUNCT
fnp-3528	904	10	shinohara	shinohara	PROPN
fnp-3528	904	11	,	,	PUNCT
fnp-3528	904	12	m.	m.	NOUN
fnp-3528	904	13	;	;	PUNCT
fnp-3528	904	14	frisch	frisch	VERB
fnp-3528	904	15	-	-	PUNCT
fnp-3528	904	16	daiello	daiello	PROPN
fnp-3528	904	17	,	,	PUNCT
fnp-3528	904	18	j.	j.	PROPN
fnp-3528	904	19	;	;	PUNCT
fnp-3528	904	20	ma	ma	PROPN
fnp-3528	904	21	,	,	PUNCT
fnp-3528	904	22	l.	l.	PROPN
fnp-3528	904	23	;	;	PUNCT
fnp-3528	904	24	yamazaki	yamazaki	PROPN
fnp-3528	904	25	,	,	PUNCT
fnp-3528	904	26	y.	y.	PROPN
fnp-3528	904	27	;	;	PUNCT
fnp-3528	904	28	tachibana	tachibana	PROPN
fnp-3528	904	29	,	,	PUNCT
fnp-3528	904	30	m.	m.	NOUN
fnp-3528	904	31	;	;	PUNCT
fnp-3528	904	32	younkin	younkin	NOUN
fnp-3528	904	33	,	,	PUNCT
fnp-3528	904	34	l.	l.	PROPN
fnp-3528	904	35	;	;	PUNCT
fnp-3528	904	36	kurti	kurti	PROPN
fnp-3528	904	37	,	,	PUNCT
fnp-3528	904	38	a.	a.	NOUN
fnp-3528	904	39	;	;	PUNCT
fnp-3528	904	40	carrasquillo	carrasquillo	PROPN
fnp-3528	904	41	,	,	PUNCT
fnp-3528	904	42	m.	m.	NOUN
fnp-3528	904	43	m.	m.	NOUN
fnp-3528	904	44	;	;	PUNCT
fnp-3528	904	45	zou	zou	PROPN
fnp-3528	904	46	,	,	PUNCT
fnp-3528	904	47	f.	f.	PROPN
fnp-3528	904	48	;	;	PUNCT
fnp-3528	904	49	sevlever	sevlever	PROPN
fnp-3528	904	50	,	,	PUNCT
fnp-3528	904	51	d.	d.	PROPN
fnp-3528	904	52	;	;	PUNCT
fnp-3528	904	53	bisceglio	bisceglio	NOUN
fnp-3528	904	54	,	,	PUNCT
fnp-3528	904	55	g.	g.	PROPN
fnp-3528	904	56	;	;	PUNCT
fnp-3528	904	57	gan	gan	PROPN
fnp-3528	904	58	,	,	PUNCT
fnp-3528	904	59	m.	m.	NOUN
fnp-3528	904	60	;	;	PUNCT
fnp-3528	904	61	fol	fol	X
fnp-3528	904	62	,	,	PUNCT
fnp-3528	904	63	r.	r.	PROPN
fnp-3528	904	64	;	;	PUNCT
fnp-3528	904	65	knight	knight	NOUN
fnp-3528	904	66	,	,	PUNCT
fnp-3528	904	67	p.	p.	PROPN
fnp-3528	904	68	;	;	PUNCT
fnp-3528	904	69	wang	wang	PROPN
fnp-3528	904	70	,	,	PUNCT
fnp-3528	904	71	m.	m.	NOUN
fnp-3528	904	72	;	;	PUNCT
fnp-3528	904	73	han	han	PROPN
fnp-3528	904	74	,	,	PUNCT
fnp-3528	904	75	x.	x.	NOUN
fnp-3528	904	76	;	;	PUNCT
fnp-3528	904	77	fryer	fryer	NOUN
fnp-3528	904	78	,	,	PUNCT
fnp-3528	904	79	j.	j.	PROPN
fnp-3528	904	80	d.	d.	PROPN
fnp-3528	904	81	;	;	PUNCT
fnp-3528	904	82	fitzgerald	fitzgerald	PROPN
fnp-3528	904	83	,	,	PUNCT
fnp-3528	904	84	m.	m.	NOUN
fnp-3528	904	85	l.	l.	PROPN
fnp-3528	904	86	;	;	PUNCT
fnp-3528	904	87	ohyagi	ohyagi	ADV
fnp-3528	904	88	,	,	PUNCT
fnp-3528	904	89	y.	y.	PROPN
fnp-3528	904	90	;	;	PUNCT
fnp-3528	904	91	younkin	younkin	NOUN
fnp-3528	904	92	,	,	PUNCT
fnp-3528	904	93	s.	s.	PROPN
fnp-3528	904	94	g.	g.	PROPN
fnp-3528	904	95	;	;	PUNCT
fnp-3528	904	96	bu	bu	PROPN
fnp-3528	904	97	,	,	PUNCT
fnp-3528	904	98	g.	g.	PROPN
fnp-3528	904	99	;	;	PUNCT
fnp-3528	904	100	kanekiyo	kanekiyo	PROPN
fnp-3528	904	101	,	,	PUNCT
fnp-3528	904	102	t.	t.	NOUN
fnp-3528	904	103	abca7	abca7	PROPN
fnp-3528	904	104	deficiency	deficiency	NOUN
fnp-3528	904	105	accelerates	accelerate	VERB
fnp-3528	904	106	amyloid	amyloid	NOUN
fnp-3528	904	107	-	-	PUNCT
fnp-3528	904	108	beta	beta	NOUN
fnp-3528	904	109	generation	generation	NOUN
fnp-3528	904	110	and	and	CCONJ
fnp-3528	904	111	alzheimer	alzheimer	NOUN
fnp-3528	904	112	's	's	PART
fnp-3528	904	113	neuronal	neuronal	ADJ
fnp-3528	904	114	pathology	pathology	NOUN
fnp-3528	904	115	.	.	PUNCT
fnp-3528	905	1	j	j	PROPN
fnp-3528	905	2	neurosci	neurosci	PROPN
fnp-3528	905	3	2016	2016	NUM
fnp-3528	905	4	,	,	PUNCT
fnp-3528	905	5	36	36	NUM
fnp-3528	905	6	,	,	PUNCT
fnp-3528	905	7	3848	3848	NUM
fnp-3528	905	8	-	-	SYM
fnp-3528	905	9	59	59	NUM
fnp-3528	905	10	.	.	PUNCT
fnp-3528	906	1	aikawa	aikawa	PROPN
fnp-3528	906	2	,	,	PUNCT
fnp-3528	906	3	t.	t.	PROPN
fnp-3528	906	4	;	;	PUNCT
fnp-3528	906	5	ren	ren	PROPN
fnp-3528	906	6	,	,	PUNCT
fnp-3528	906	7	y.	y.	PROPN
fnp-3528	906	8	;	;	PUNCT
fnp-3528	906	9	yamazaki	yamazaki	PROPN
fnp-3528	906	10	,	,	PUNCT
fnp-3528	906	11	y.	y.	PROPN
fnp-3528	906	12	;	;	PUNCT
fnp-3528	906	13	tachibana	tachibana	PROPN
fnp-3528	906	14	,	,	PUNCT
fnp-3528	906	15	m.	m.	NOUN
fnp-3528	906	16	;	;	PUNCT
fnp-3528	906	17	johnson	johnson	PROPN
fnp-3528	906	18	,	,	PUNCT
fnp-3528	906	19	m.	m.	PROPN
fnp-3528	906	20	r.	r.	PROPN
fnp-3528	906	21	;	;	PUNCT
fnp-3528	906	22	anderson	anderson	PROPN
fnp-3528	906	23	,	,	PUNCT
fnp-3528	906	24	c.	c.	PROPN
fnp-3528	906	25	t.	t.	PROPN
fnp-3528	906	26	;	;	PUNCT
fnp-3528	906	27	martens	martens	PROPN
fnp-3528	906	28	,	,	PUNCT
fnp-3528	906	29	y.	y.	PROPN
fnp-3528	906	30	a.	a.	PROPN
fnp-3528	906	31	;	;	PUNCT
fnp-3528	906	32	holm	holm	PROPN
fnp-3528	906	33	,	,	PUNCT
fnp-3528	906	34	m.	m.	NOUN
fnp-3528	906	35	l.	l.	PROPN
fnp-3528	906	36	;	;	PUNCT
fnp-3528	906	37	asmann	asmann	PROPN
fnp-3528	906	38	,	,	PUNCT
fnp-3528	906	39	y.	y.	PROPN
fnp-3528	906	40	w.	w.	PROPN
fnp-3528	906	41	;	;	PUNCT
fnp-3528	906	42	saito	saito	PROPN
fnp-3528	906	43	,	,	PUNCT
fnp-3528	906	44	t.	t.	PROPN
fnp-3528	906	45	;	;	PUNCT
fnp-3528	906	46	saido	saido	PROPN
fnp-3528	906	47	,	,	PUNCT
fnp-3528	906	48	t.	t.	PROPN
fnp-3528	906	49	c.	c.	PROPN
fnp-3528	906	50	;	;	PUNCT
fnp-3528	906	51	fitzgerald	fitzgerald	PROPN
fnp-3528	906	52	,	,	PUNCT
fnp-3528	906	53	m.	m.	NOUN
fnp-3528	906	54	l.	l.	PROPN
fnp-3528	906	55	;	;	PUNCT
fnp-3528	906	56	bu	bu	PROPN
fnp-3528	906	57	,	,	PUNCT
fnp-3528	906	58	g.	g.	PROPN
fnp-3528	906	59	;	;	PUNCT
fnp-3528	906	60	kanekiyo	kanekiyo	PROPN
fnp-3528	906	61	,	,	PUNCT
fnp-3528	906	62	t.	t.	PROPN
fnp-3528	906	63	abca7	abca7	PROPN
fnp-3528	906	64	haplodeficiency	haplodeficiency	PROPN
fnp-3528	906	65	disturbs	disturb	VERB
fnp-3528	906	66	microglial	microglial	ADJ
fnp-3528	906	67	immune	immune	ADJ
fnp-3528	906	68	responses	response	NOUN
fnp-3528	906	69	in	in	ADP
fnp-3528	906	70	the	the	DET
fnp-3528	906	71	mouse	mouse	NOUN
fnp-3528	906	72	brain	brain	NOUN
fnp-3528	906	73	.	.	PUNCT
fnp-3528	907	1	proc	proc	PROPN
fnp-3528	907	2	natl	natl	PROPN
fnp-3528	907	3	acad	acad	PROPN
fnp-3528	907	4	sci	sci	PROPN
fnp-3528	907	5	u	u	PROPN
fnp-3528	907	6	s	s	PROPN
fnp-3528	907	7	a	a	DET
fnp-3528	907	8	2019	2019	NUM
fnp-3528	907	9	,	,	PUNCT
fnp-3528	907	10	116	116	NUM
fnp-3528	907	11	,	,	PUNCT
fnp-3528	907	12	23790	23790	NUM
fnp-3528	907	13	-	-	SYM
fnp-3528	907	14	23796	23796	NUM
fnp-3528	907	15	.	.	PUNCT
fnp-3528	908	1	zissimopoulos	zissimopoulos	PROPN
fnp-3528	908	2	,	,	PUNCT
fnp-3528	908	3	j.	j.	PROPN
fnp-3528	908	4	m.	m.	PROPN
fnp-3528	908	5	;	;	PUNCT
fnp-3528	908	6	barthold	barthold	VERB
fnp-3528	908	7	,	,	PUNCT
fnp-3528	908	8	d.	d.	PROPN
fnp-3528	908	9	;	;	PUNCT
fnp-3528	908	10	brinton	brinton	PROPN
fnp-3528	908	11	,	,	PUNCT
fnp-3528	908	12	r.	r.	PROPN
fnp-3528	908	13	d.	d.	PROPN
fnp-3528	908	14	;	;	PUNCT
fnp-3528	908	15	joyce	joyce	PROPN
fnp-3528	908	16	,	,	PUNCT
fnp-3528	908	17	g.	g.	PROPN
fnp-3528	908	18	sex	sex	NOUN
fnp-3528	908	19	and	and	CCONJ
fnp-3528	908	20	race	race	NOUN
fnp-3528	908	21	differences	difference	NOUN
fnp-3528	908	22	in	in	ADP
fnp-3528	908	23	the	the	DET
fnp-3528	908	24	association	association	NOUN
fnp-3528	908	25	between	between	ADP
fnp-3528	908	26	statin	statin	PROPN
fnp-3528	908	27	use	use	NOUN
fnp-3528	908	28	and	and	CCONJ
fnp-3528	908	29	the	the	DET
fnp-3528	908	30	incidence	incidence	NOUN
fnp-3528	908	31	of	of	ADP
fnp-3528	908	32	alzheimer	alzheimer	PROPN
fnp-3528	908	33	disease	disease	PROPN
fnp-3528	908	34	.	.	PUNCT
fnp-3528	909	1	jama	jama	PROPN
fnp-3528	909	2	neurolog	neurolog	VERB
fnp-3528	909	3	2017	2017	NUM
fnp-3528	909	4	,	,	PUNCT
fnp-3528	909	5	74	74	NUM
fnp-3528	909	6	,	,	PUNCT
fnp-3528	909	7	225	225	NUM
fnp-3528	909	8	-	-	SYM
fnp-3528	909	9	32	32	NUM
fnp-3528	909	10	.	.	PUNCT
fnp-3528	910	1	yang	yang	PROPN
fnp-3528	910	2	,	,	PUNCT
fnp-3528	910	3	c.	c.	PROPN
fnp-3528	910	4	;	;	PUNCT
fnp-3528	910	5	yuan	yuan	PROPN
fnp-3528	910	6	,	,	PUNCT
fnp-3528	910	7	h.	h.	PROPN
fnp-3528	910	8	;	;	PUNCT
fnp-3528	910	9	gu	gu	PROPN
fnp-3528	910	10	,	,	PUNCT
fnp-3528	910	11	j.	j.	PROPN
fnp-3528	910	12	;	;	PUNCT
fnp-3528	910	13	xu	xu	PROPN
fnp-3528	910	14	,	,	PUNCT
fnp-3528	910	15	d.	d.	PROPN
fnp-3528	910	16	;	;	PUNCT
fnp-3528	910	17	wang	wang	PROPN
fnp-3528	910	18	,	,	PUNCT
fnp-3528	910	19	m.	m.	NOUN
fnp-3528	910	20	;	;	PUNCT
fnp-3528	910	21	qiao	qiao	PROPN
fnp-3528	910	22	,	,	PUNCT
fnp-3528	910	23	j.	j.	PROPN
fnp-3528	910	24	;	;	PUNCT
fnp-3528	910	25	yang	yang	PROPN
fnp-3528	910	26	,	,	PUNCT
fnp-3528	910	27	x.	x.	PROPN
fnp-3528	910	28	;	;	PUNCT
fnp-3528	910	29	zhang	zhang	PROPN
fnp-3528	910	30	,	,	PUNCT
fnp-3528	910	31	j.	j.	PROPN
fnp-3528	910	32	;	;	PUNCT
fnp-3528	910	33	yao	yao	PROPN
fnp-3528	910	34	,	,	PUNCT
fnp-3528	910	35	m.	m.	NOUN
fnp-3528	910	36	;	;	PUNCT
fnp-3528	910	37	gu	gu	PROPN
fnp-3528	910	38	,	,	PUNCT
fnp-3528	910	39	j.	j.	PROPN
fnp-3528	910	40	;	;	PUNCT
fnp-3528	910	41	tu	tu	PROPN
fnp-3528	910	42	,	,	PUNCT
fnp-3528	910	43	h.	h.	PROPN
fnp-3528	910	44	;	;	PUNCT
fnp-3528	910	45	gan	gan	PROPN
fnp-3528	910	46	,	,	PUNCT
fnp-3528	910	47	y.	y.	PROPN
fnp-3528	910	48	abca8	abca8	PROPN
fnp-3528	910	49	-	-	PUNCT
fnp-3528	910	50	mediated	mediate	VERB
fnp-3528	910	51	efflux	efflux	NOUN
fnp-3528	910	52	of	of	ADP
fnp-3528	910	53	taurocholic	taurocholic	ADJ
fnp-3528	910	54	acid	acid	NOUN
fnp-3528	910	55	contributes	contribute	VERB
fnp-3528	910	56	to	to	PART
fnp-3528	910	57	gemcitabine	gemcitabine	VERB
fnp-3528	910	58	insensitivity	insensitivity	NOUN
fnp-3528	910	59	in	in	ADP
fnp-3528	910	60	human	human	ADJ
fnp-3528	910	61	pancreatic	pancreatic	ADJ
fnp-3528	910	62	cancer	cancer	NOUN
fnp-3528	910	63	via	via	ADP
fnp-3528	910	64	the	the	DET
fnp-3528	910	65	s1pr2	s1pr2	NOUN
fnp-3528	910	66	-	-	PUNCT
fnp-3528	910	67	erk	erk	NOUN
fnp-3528	910	68	pathway	pathway	NOUN
fnp-3528	910	69	.	.	PUNCT
fnp-3528	911	1	cell	cell	NOUN
fnp-3528	911	2	death	death	NOUN
fnp-3528	911	3	discov	discov	PROPN
fnp-3528	911	4	2021	2021	NUM
fnp-3528	911	5	,	,	PUNCT
fnp-3528	911	6	7	7	NUM
fnp-3528	911	7	,	,	PUNCT
fnp-3528	911	8	6	6	NUM
fnp-3528	911	9	.	.	X
fnp-3528	911	10	tsuruoka	tsuruoka	NOUN
fnp-3528	911	11	,	,	PUNCT
fnp-3528	911	12	s.	s.	PROPN
fnp-3528	911	13	;	;	PUNCT
fnp-3528	911	14	ishibashi	ishibashi	PROPN
fnp-3528	911	15	,	,	PUNCT
fnp-3528	911	16	k.	k.	PROPN
fnp-3528	911	17	;	;	PUNCT
fnp-3528	911	18	yamamoto	yamamoto	PROPN
fnp-3528	911	19	,	,	PUNCT
fnp-3528	911	20	h.	h.	PROPN
fnp-3528	911	21	;	;	PUNCT
fnp-3528	911	22	wakaumi	wakaumi	PROPN
fnp-3528	911	23	,	,	PUNCT
fnp-3528	911	24	m.	m.	NOUN
fnp-3528	911	25	;	;	PUNCT
fnp-3528	911	26	suzuki	suzuki	PROPN
fnp-3528	911	27	,	,	PUNCT
fnp-3528	911	28	m.	m.	NOUN
fnp-3528	911	29	;	;	PUNCT
fnp-3528	911	30	schwartz	schwartz	PROPN
fnp-3528	911	31	,	,	PUNCT
fnp-3528	911	32	g.	g.	PROPN
fnp-3528	911	33	j.	j.	PROPN
fnp-3528	911	34	;	;	PUNCT
fnp-3528	911	35	imai	imai	PROPN
fnp-3528	911	36	,	,	PUNCT
fnp-3528	911	37	m.	m.	NOUN
fnp-3528	911	38	;	;	PUNCT
fnp-3528	911	39	fujimura	fujimura	NOUN
fnp-3528	911	40	,	,	PUNCT
fnp-3528	911	41	a.	a.	NOUN
fnp-3528	911	42	functional	functional	ADJ
fnp-3528	911	43	analysis	analysis	NOUN
fnp-3528	911	44	of	of	ADP
fnp-3528	911	45	abca8	abca8	PROPN
fnp-3528	911	46	,	,	PUNCT
fnp-3528	911	47	a	a	DET
fnp-3528	911	48	new	new	ADJ
fnp-3528	911	49	drug	drug	NOUN
fnp-3528	911	50	transporter	transporter	NOUN
fnp-3528	911	51	.	.	PUNCT
fnp-3528	912	1	biochem	biochem	PROPN
fnp-3528	912	2	biophys	biophys	PROPN
fnp-3528	912	3	res	res	PROPN
fnp-3528	912	4	commun	commun	PROPN
fnp-3528	912	5	2002	2002	NUM
fnp-3528	912	6	,	,	PUNCT
fnp-3528	912	7	298	298	NUM
fnp-3528	912	8	,	,	PUNCT
fnp-3528	912	9	41	41	NUM
fnp-3528	912	10	-	-	SYM
fnp-3528	912	11	5	5	NUM
fnp-3528	912	12	.	.	PUNCT
fnp-3528	913	1	akiyama	akiyama	PROPN
fnp-3528	913	2	,	,	PUNCT
fnp-3528	913	3	m.	m.	NOUN
fnp-3528	913	4	;	;	PUNCT
fnp-3528	913	5	sugiyama	sugiyama	NOUN
fnp-3528	913	6	-	-	PUNCT
fnp-3528	913	7	nakagiri	nakagiri	PROPN
fnp-3528	913	8	,	,	PUNCT
fnp-3528	913	9	y.	y.	PROPN
fnp-3528	913	10	;	;	PUNCT
fnp-3528	913	11	sakai	sakai	PROPN
fnp-3528	913	12	,	,	PUNCT
fnp-3528	913	13	k.	k.	PROPN
fnp-3528	913	14	;	;	PUNCT
fnp-3528	913	15	mcmillan	mcmillan	PROPN
fnp-3528	913	16	,	,	PUNCT
fnp-3528	913	17	j.	j.	PROPN
fnp-3528	913	18	r.	r.	PROPN
fnp-3528	913	19	;	;	PUNCT
fnp-3528	913	20	goto	goto	NOUN
fnp-3528	913	21	,	,	PUNCT
fnp-3528	913	22	m.	m.	NOUN
fnp-3528	913	23	;	;	PUNCT
fnp-3528	913	24	arita	arita	PROPN
fnp-3528	913	25	,	,	PUNCT
fnp-3528	913	26	k.	k.	PROPN
fnp-3528	913	27	;	;	PUNCT
fnp-3528	913	28	tsuji	tsuji	PROPN
fnp-3528	913	29	-	-	PUNCT
fnp-3528	913	30	abe	abe	PROPN
fnp-3528	913	31	,	,	PUNCT
fnp-3528	913	32	y.	y.	NOUN
fnp-3528	913	33	;	;	PUNCT
fnp-3528	913	34	tabata	tabata	NOUN
fnp-3528	913	35	,	,	PUNCT
fnp-3528	913	36	n.	n.	NOUN
fnp-3528	913	37	;	;	PUNCT
fnp-3528	913	38	matsuoka	matsuoka	PROPN
fnp-3528	913	39	,	,	PUNCT
fnp-3528	913	40	k.	k.	PROPN
fnp-3528	913	41	;	;	PUNCT
fnp-3528	913	42	sasaki	sasaki	PROPN
fnp-3528	913	43	,	,	PUNCT
fnp-3528	913	44	r.	r.	PROPN
fnp-3528	913	45	;	;	PUNCT
fnp-3528	913	46	sawamura	sawamura	PROPN
fnp-3528	913	47	,	,	PUNCT
fnp-3528	913	48	d.	d.	PROPN
fnp-3528	913	49	;	;	PUNCT
fnp-3528	913	50	shimizu	shimizu	PROPN
fnp-3528	913	51	,	,	PUNCT
fnp-3528	913	52	h.	h.	PROPN
fnp-3528	913	53	mutations	mutation	NOUN
fnp-3528	913	54	in	in	ADP
fnp-3528	913	55	lipid	lipid	NOUN
fnp-3528	913	56	transporter	transporter	NOUN
fnp-3528	913	57	abca12	abca12	NOUN
fnp-3528	913	58	in	in	ADP
fnp-3528	913	59	harlequin	harlequin	PROPN
fnp-3528	913	60	ichthyosis	ichthyosis	NOUN
fnp-3528	913	61	and	and	CCONJ
fnp-3528	913	62	functional	functional	ADJ
fnp-3528	913	63	recovery	recovery	NOUN
fnp-3528	913	64	by	by	ADP
fnp-3528	913	65	corrective	corrective	ADJ
fnp-3528	913	66	gene	gene	NOUN
fnp-3528	913	67	transfer	transfer	NOUN
fnp-3528	913	68	.	.	PUNCT
fnp-3528	914	1	j	j	PROPN
fnp-3528	914	2	clin	clin	PROPN
fnp-3528	914	3	invest	invest	VERB
fnp-3528	914	4	2005	2005	NUM
fnp-3528	914	5	,	,	PUNCT
fnp-3528	914	6	115	115	NUM
fnp-3528	914	7	,	,	PUNCT
fnp-3528	914	8	1777	1777	NUM
fnp-3528	914	9	-	-	SYM
fnp-3528	914	10	84	84	NUM
fnp-3528	914	11	.	.	PUNCT
fnp-3528	915	1	kelsell	kelsell	PROPN
fnp-3528	915	2	,	,	PUNCT
fnp-3528	915	3	d.	d.	PROPN
fnp-3528	915	4	p.	p.	PROPN
fnp-3528	915	5	;	;	PUNCT
fnp-3528	915	6	norgett	norgett	PROPN
fnp-3528	915	7	,	,	PUNCT
fnp-3528	915	8	e.	e.	PROPN
fnp-3528	915	9	e.	e.	PROPN
fnp-3528	915	10	;	;	PUNCT
fnp-3528	915	11	unsworth	unsworth	PROPN
fnp-3528	915	12	,	,	PUNCT
fnp-3528	915	13	h.	h.	PROPN
fnp-3528	915	14	;	;	PUNCT
fnp-3528	915	15	teh	teh	PROPN
fnp-3528	915	16	,	,	PUNCT
fnp-3528	915	17	m.	m.	NOUN
fnp-3528	915	18	t.	t.	PROPN
fnp-3528	915	19	;	;	PUNCT
fnp-3528	915	20	cullup	cullup	PROPN
fnp-3528	915	21	,	,	PUNCT
fnp-3528	915	22	t.	t.	PROPN
fnp-3528	915	23	;	;	PUNCT
fnp-3528	915	24	mein	mein	PROPN
fnp-3528	915	25	,	,	PUNCT
fnp-3528	915	26	c.	c.	PROPN
fnp-3528	915	27	a.	a.	PROPN
fnp-3528	915	28	;	;	PUNCT
fnp-3528	915	29	dopping	dopping	NOUN
fnp-3528	915	30	-	-	PUNCT
fnp-3528	915	31	hepenstal	hepenstal	PROPN
fnp-3528	915	32	,	,	PUNCT
fnp-3528	915	33	p.	p.	PROPN
fnp-3528	915	34	j.	j.	PROPN
fnp-3528	915	35	;	;	PUNCT
fnp-3528	915	36	dale	dale	PROPN
fnp-3528	915	37	,	,	PUNCT
fnp-3528	915	38	b.	b.	PROPN
fnp-3528	915	39	a.	a.	PROPN
fnp-3528	915	40	;	;	PUNCT
fnp-3528	915	41	tadini	tadini	PROPN
fnp-3528	915	42	,	,	PUNCT
fnp-3528	915	43	g.	g.	PROPN
fnp-3528	915	44	;	;	PUNCT
fnp-3528	915	45	fleckman	fleckman	NOUN
fnp-3528	915	46	,	,	PUNCT
fnp-3528	915	47	p.	p.	NOUN
fnp-3528	915	48	;	;	PUNCT
fnp-3528	915	49	stephens	stephens	PROPN
fnp-3528	915	50	,	,	PUNCT
fnp-3528	915	51	k.	k.	PROPN
fnp-3528	915	52	g.	g.	PROPN
fnp-3528	915	53	;	;	PUNCT
fnp-3528	915	54	sybert	sybert	PROPN
fnp-3528	915	55	,	,	PUNCT
fnp-3528	915	56	v.	v.	PROPN
fnp-3528	915	57	p.	p.	PROPN
fnp-3528	915	58	;	;	PUNCT
fnp-3528	915	59	mallory	mallory	PROPN
fnp-3528	915	60	,	,	PUNCT
fnp-3528	915	61	s.	s.	PROPN
fnp-3528	915	62	b.	b.	PROPN
fnp-3528	915	63	;	;	PUNCT
fnp-3528	915	64	north	north	PROPN
fnp-3528	915	65	,	,	PUNCT
fnp-3528	915	66	b.	b.	PROPN
fnp-3528	916	1	v.	v.	PROPN
fnp-3528	916	2	;	;	PUNCT
fnp-3528	916	3	witt	witt	PROPN
fnp-3528	916	4	,	,	PUNCT
fnp-3528	916	5	d.	d.	PROPN
fnp-3528	916	6	r.	r.	PROPN
fnp-3528	916	7	;	;	PUNCT
fnp-3528	916	8	sprecher	sprecher	PROPN
fnp-3528	916	9	,	,	PUNCT
fnp-3528	916	10	e.	e.	PROPN
fnp-3528	916	11	;	;	PUNCT
fnp-3528	916	12	taylor	taylor	PROPN
fnp-3528	916	13	,	,	PUNCT
fnp-3528	916	14	a.	a.	PROPN
fnp-3528	916	15	e.	e.	PROPN
fnp-3528	916	16	;	;	PUNCT
fnp-3528	916	17	ilchyshyn	ilchyshyn	PROPN
fnp-3528	916	18	,	,	PUNCT
fnp-3528	916	19	a.	a.	PROPN
fnp-3528	916	20	;	;	PUNCT
fnp-3528	916	21	kennedy	kennedy	PROPN
fnp-3528	916	22	,	,	PUNCT
fnp-3528	916	23	c.	c.	PROPN
fnp-3528	916	24	t.	t.	PROPN
fnp-3528	916	25	;	;	PUNCT
fnp-3528	916	26	goodyear	goodyear	PROPN
fnp-3528	916	27	,	,	PUNCT
fnp-3528	916	28	h.	h.	PROPN
fnp-3528	916	29	;	;	PUNCT
fnp-3528	916	30	moss	moss	PROPN
fnp-3528	916	31	,	,	PUNCT
fnp-3528	916	32	c.	c.	PROPN
fnp-3528	916	33	;	;	PUNCT
fnp-3528	916	34	paige	paige	PROPN
fnp-3528	916	35	,	,	PUNCT
fnp-3528	916	36	d.	d.	PROPN
fnp-3528	916	37	;	;	PUNCT
fnp-3528	916	38	harper	harper	PROPN
fnp-3528	916	39	,	,	PUNCT
fnp-3528	916	40	j.	j.	PROPN
fnp-3528	916	41	i.	i.	PROPN
fnp-3528	916	42	;	;	PUNCT
fnp-3528	916	43	young	young	ADJ
fnp-3528	916	44	,	,	PUNCT
fnp-3528	916	45	b.	b.	PROPN
fnp-3528	916	46	d.	d.	PROPN
fnp-3528	916	47	;	;	PUNCT
fnp-3528	916	48	leigh	leigh	PROPN
fnp-3528	916	49	,	,	PUNCT
fnp-3528	916	50	i.	i.	NOUN
fnp-3528	916	51	m.	m.	PROPN
fnp-3528	916	52	;	;	PUNCT
fnp-3528	916	53	eady	eady	PROPN
fnp-3528	916	54	,	,	PUNCT
fnp-3528	916	55	r.	r.	PROPN
fnp-3528	916	56	a.	a.	PROPN
fnp-3528	916	57	;	;	PUNCT
fnp-3528	916	58	o'toole	o'toole	PROPN
fnp-3528	916	59	,	,	PUNCT
fnp-3528	916	60	e.	e.	PROPN
fnp-3528	916	61	a.	a.	PROPN
fnp-3528	916	62	mutations	mutation	NOUN
fnp-3528	916	63	in	in	ADP
fnp-3528	916	64	abca12	abca12	NOUN
fnp-3528	916	65	underlie	underlie	ADJ
fnp-3528	916	66	the	the	DET
fnp-3528	916	67	severe	severe	ADJ
fnp-3528	916	68	congenital	congenital	ADJ
fnp-3528	916	69	skin	skin	NOUN
fnp-3528	916	70	disease	disease	NOUN
fnp-3528	916	71	harlequin	harlequin	PROPN
fnp-3528	916	72	ichthyosis	ichthyosis	NOUN
fnp-3528	916	73	.	.	PUNCT
fnp-3528	917	1	am	be	AUX
fnp-3528	917	2	j	j	PROPN
fnp-3528	917	3	hum	hum	PROPN
fnp-3528	917	4	genet	genet	PROPN
fnp-3528	917	5	2005	2005	NUM
fnp-3528	917	6	,	,	PUNCT
fnp-3528	917	7	76	76	NUM
fnp-3528	917	8	,	,	PUNCT
fnp-3528	917	9	794	794	NUM
fnp-3528	917	10	-	-	SYM
fnp-3528	917	11	803	803	NUM
fnp-3528	917	12	.	.	PUNCT
fnp-3528	918	1	lefévre	lefévre	NOUN
fnp-3528	918	2	,	,	PUNCT
fnp-3528	918	3	c.	c.	NOUN
fnp-3528	918	4	;	;	PUNCT
fnp-3528	918	5	audebert	audebert	ADJ
fnp-3528	918	6	,	,	PUNCT
fnp-3528	918	7	s.	s.	PROPN
fnp-3528	918	8	;	;	PUNCT
fnp-3528	918	9	jobard	jobard	ADV
fnp-3528	918	10	,	,	PUNCT
fnp-3528	918	11	f.	f.	PROPN
fnp-3528	918	12	;	;	PUNCT
fnp-3528	918	13	bouadjar	bouadjar	PROPN
fnp-3528	918	14	,	,	PUNCT
fnp-3528	918	15	b.	b.	PROPN
fnp-3528	918	16	;	;	PUNCT
fnp-3528	918	17	lakhdar	lakhdar	PROPN
fnp-3528	918	18	,	,	PUNCT
fnp-3528	918	19	h.	h.	PROPN
fnp-3528	918	20	;	;	PUNCT
fnp-3528	918	21	boughdene	boughdene	NOUN
fnp-3528	918	22	-	-	PUNCT
fnp-3528	918	23	stambouli	stambouli	NOUN
fnp-3528	918	24	,	,	PUNCT
fnp-3528	918	25	o.	o.	PROPN
fnp-3528	918	26	;	;	PUNCT
fnp-3528	918	27	blanchet	blanchet	PROPN
fnp-3528	918	28	-	-	PUNCT
fnp-3528	918	29	bardon	bardon	PROPN
fnp-3528	918	30	,	,	PUNCT
fnp-3528	918	31	c.	c.	PROPN
fnp-3528	918	32	;	;	PUNCT
fnp-3528	918	33	heilig	heilig	PROPN
fnp-3528	918	34	,	,	PUNCT
fnp-3528	918	35	r.	r.	PROPN
fnp-3528	918	36	;	;	PUNCT
fnp-3528	918	37	foglio	foglio	PROPN
fnp-3528	918	38	,	,	PUNCT
fnp-3528	918	39	m.	m.	NOUN
fnp-3528	918	40	;	;	PUNCT
fnp-3528	918	41	weissenbach	weissenbach	ADV
fnp-3528	918	42	,	,	PUNCT
fnp-3528	918	43	j.	j.	PROPN
fnp-3528	918	44	;	;	PUNCT
fnp-3528	918	45	lathrop	lathrop	PROPN
fnp-3528	918	46	,	,	PUNCT
fnp-3528	918	47	m.	m.	NOUN
fnp-3528	918	48	;	;	PUNCT
fnp-3528	918	49	prud'homme	prud'homme	PROPN
fnp-3528	918	50	,	,	PUNCT
fnp-3528	918	51	j.	j.	PROPN
fnp-3528	918	52	f.	f.	PROPN
fnp-3528	918	53	;	;	PUNCT
fnp-3528	918	54	fischer	fischer	PROPN
fnp-3528	918	55	,	,	PUNCT
fnp-3528	918	56	j.	j.	PROPN
fnp-3528	918	57	mutations	mutation	NOUN
fnp-3528	918	58	in	in	ADP
fnp-3528	918	59	the	the	DET
fnp-3528	918	60	transporter	transporter	NOUN
fnp-3528	918	61	abca12	abca12	NOUN
fnp-3528	918	62	are	be	AUX
fnp-3528	918	63	associated	associate	VERB
fnp-3528	918	64	with	with	ADP
fnp-3528	918	65	lamellar	lamellar	ADJ
fnp-3528	918	66	ichthyosis	ichthyosis	NOUN
fnp-3528	918	67	type	type	NOUN
fnp-3528	918	68	2	2	NUM
fnp-3528	918	69	.	.	NOUN
fnp-3528	918	70	hum	hum	NOUN
fnp-3528	918	71	mol	mol	ADP
fnp-3528	918	72	genet	genet	PROPN
fnp-3528	918	73	2003	2003	NUM
fnp-3528	918	74	,	,	PUNCT
fnp-3528	918	75	12	12	NUM
fnp-3528	918	76	,	,	PUNCT
fnp-3528	918	77	2369	2369	NUM
fnp-3528	918	78	-	-	SYM
fnp-3528	918	79	78	78	NUM
fnp-3528	918	80	.	.	PUNCT
fnp-3528	919	1	ohkubo	ohkubo	NOUN
fnp-3528	919	2	,	,	PUNCT
fnp-3528	919	3	t.	t.	PROPN
fnp-3528	919	4	;	;	PUNCT
fnp-3528	919	5	shibata	shibata	PROPN
fnp-3528	919	6	,	,	PUNCT
fnp-3528	919	7	n.	n.	NOUN
fnp-3528	919	8	;	;	PUNCT
fnp-3528	919	9	ohnuma	ohnuma	NOUN
fnp-3528	919	10	,	,	PUNCT
fnp-3528	919	11	t.	t.	PROPN
fnp-3528	919	12	;	;	PUNCT
fnp-3528	919	13	higashi	higashi	PROPN
fnp-3528	919	14	,	,	PUNCT
fnp-3528	919	15	s.	s.	PROPN
fnp-3528	919	16	;	;	PUNCT
fnp-3528	919	17	usui	usui	PROPN
fnp-3528	919	18	,	,	PUNCT
fnp-3528	919	19	c.	c.	PROPN
fnp-3528	919	20	;	;	PUNCT
fnp-3528	919	21	ueki	ueki	PROPN
fnp-3528	919	22	,	,	PUNCT
fnp-3528	919	23	a.	a.	NOUN
fnp-3528	919	24	;	;	PUNCT
fnp-3528	919	25	nagao	nagao	ADJ
fnp-3528	919	26	,	,	PUNCT
fnp-3528	919	27	m.	m.	NOUN
fnp-3528	919	28	;	;	PUNCT
fnp-3528	919	29	arai	arai	PROPN
fnp-3528	919	30	,	,	PUNCT
fnp-3528	919	31	h.	h.	PROPN
fnp-3528	920	1	no	no	DET
fnp-3528	920	2	genetic	genetic	ADJ
fnp-3528	920	3	association	association	NOUN
fnp-3528	920	4	between	between	ADP
fnp-3528	920	5	atp	atp	PROPN
fnp-3528	920	6	binding	bind	VERB
fnp-3528	920	7	cassette	cassette	NOUN
fnp-3528	920	8	proteins	protein	NOUN
fnp-3528	920	9	and	and	CCONJ
fnp-3528	920	10	japanese	japanese	ADJ
fnp-3528	920	11	sporadic	sporadic	ADJ
fnp-3528	920	12	alzheimer	alzheimer	PROPN
fnp-3528	920	13	's	's	PART
fnp-3528	920	14	disease	disease	NOUN
fnp-3528	920	15	.	.	PUNCT
fnp-3528	921	1	dement	dement	PROPN
fnp-3528	921	2	geriatr	geriatr	PROPN
fnp-3528	921	3	cogn	cogn	VERB
fnp-3528	921	4	disord	disord	NOUN
fnp-3528	921	5	2005	2005	NUM
fnp-3528	921	6	,	,	PUNCT
fnp-3528	921	7	20	20	NUM
fnp-3528	921	8	,	,	PUNCT
fnp-3528	921	9	95	95	NUM
fnp-3528	921	10	-	-	SYM
fnp-3528	921	11	8	8	NUM
fnp-3528	921	12	.	.	PUNCT
fnp-3528	921	13	prades	prade	NOUN
fnp-3528	921	14	,	,	PUNCT
fnp-3528	921	15	c.	c.	NOUN
fnp-3528	921	16	;	;	PUNCT
fnp-3528	921	17	arnould	arnould	PROPN
fnp-3528	921	18	,	,	PUNCT
fnp-3528	921	19	i.	i.	PROPN
fnp-3528	921	20	;	;	PUNCT
fnp-3528	921	21	annilo	annilo	ADV
fnp-3528	921	22	,	,	PUNCT
fnp-3528	921	23	t.	t.	PROPN
fnp-3528	921	24	;	;	PUNCT
fnp-3528	921	25	shulenin	shulenin	PROPN
fnp-3528	921	26	,	,	PUNCT
fnp-3528	921	27	s.	s.	PROPN
fnp-3528	921	28	;	;	PUNCT
fnp-3528	921	29	chen	chen	PROPN
fnp-3528	921	30	,	,	PUNCT
fnp-3528	921	31	z.	z.	PROPN
fnp-3528	921	32	q.	q.	PROPN
fnp-3528	921	33	;	;	PUNCT
fnp-3528	921	34	orosco	orosco	PROPN
fnp-3528	921	35	,	,	PUNCT
fnp-3528	921	36	l.	l.	PROPN
fnp-3528	921	37	;	;	PUNCT
fnp-3528	921	38	triunfol	triunfol	NOUN
fnp-3528	921	39	,	,	PUNCT
fnp-3528	921	40	m.	m.	NOUN
fnp-3528	921	41	;	;	PUNCT
fnp-3528	921	42	devaud	devaud	PROPN
fnp-3528	921	43	,	,	PUNCT
fnp-3528	921	44	c.	c.	PROPN
fnp-3528	921	45	;	;	PUNCT
fnp-3528	921	46	maintoux	maintoux	NOUN
fnp-3528	921	47	-	-	PUNCT
fnp-3528	921	48	larois	larois	NOUN
fnp-3528	921	49	,	,	PUNCT
fnp-3528	921	50	c.	c.	NOUN
fnp-3528	921	51	;	;	PUNCT
fnp-3528	921	52	lafargue	lafargue	NOUN
fnp-3528	921	53	,	,	PUNCT
fnp-3528	921	54	c.	c.	PROPN
fnp-3528	921	55	;	;	PUNCT
fnp-3528	921	56	lemoine	lemoine	PROPN
fnp-3528	921	57	,	,	PUNCT
fnp-3528	921	58	c.	c.	PROPN
fnp-3528	921	59	;	;	PUNCT
fnp-3528	921	60	denèfle	denèfle	PROPN
fnp-3528	921	61	,	,	PUNCT
fnp-3528	921	62	p.	p.	NOUN
fnp-3528	921	63	;	;	PUNCT
fnp-3528	921	64	rosier	rosier	X
fnp-3528	921	65	,	,	PUNCT
fnp-3528	921	66	m.	m.	NOUN
fnp-3528	921	67	;	;	PUNCT
fnp-3528	921	68	dean	dean	PROPN
fnp-3528	921	69	,	,	PUNCT
fnp-3528	921	70	m.	m.	NOUN
fnp-3528	921	71	the	the	DET
fnp-3528	921	72	human	human	PROPN
fnp-3528	921	73	atp	atp	PROPN
fnp-3528	921	74	binding	bind	VERB
fnp-3528	921	75	cassette	cassette	NOUN
fnp-3528	921	76	gene	gene	NOUN
fnp-3528	921	77	abca13	abca13	NOUN
fnp-3528	921	78	,	,	PUNCT
fnp-3528	921	79	located	locate	VERB
fnp-3528	921	80	on	on	ADP
fnp-3528	921	81	chromosome	chromosome	NOUN
fnp-3528	921	82	7p12.3	7p12.3	NUM
fnp-3528	921	83	,	,	PUNCT
fnp-3528	921	84	encodes	encode	VERB
fnp-3528	921	85	a	a	DET
fnp-3528	921	86	5058	5058	NUM
fnp-3528	921	87	amino	amino	NOUN
fnp-3528	921	88	acid	acid	NOUN
fnp-3528	921	89	protein	protein	NOUN
fnp-3528	921	90	with	with	ADP
fnp-3528	921	91	an	an	DET
fnp-3528	921	92	extracellular	extracellular	ADJ
fnp-3528	921	93	domain	domain	NOUN
fnp-3528	921	94	encoded	encode	VERB
fnp-3528	921	95	in	in	ADP
fnp-3528	921	96	part	part	NOUN
fnp-3528	921	97	by	by	ADP
fnp-3528	921	98	a	a	DET
fnp-3528	921	99	4.8	4.8	NUM
fnp-3528	921	100	-	-	PUNCT
fnp-3528	921	101	kb	kb	NOUN
fnp-3528	921	102	conserved	conserve	VERB
fnp-3528	921	103	exon	exon	NOUN
fnp-3528	921	104	.	.	PUNCT
fnp-3528	922	1	cytogenet	cytogenet	NOUN
fnp-3528	922	2	genome	genome	NOUN
fnp-3528	922	3	res	re	NOUN
fnp-3528	922	4	2002	2002	NUM
fnp-3528	922	5	,	,	PUNCT
fnp-3528	922	6	98	98	NUM
fnp-3528	922	7	,	,	PUNCT
fnp-3528	922	8	160	160	NUM
fnp-3528	922	9	-	-	SYM
fnp-3528	922	10	8	8	NUM
fnp-3528	922	11	.	.	PUNCT
fnp-3528	923	1	kim	kim	PROPN
fnp-3528	923	2	,	,	PUNCT
fnp-3528	923	3	w.	w.	PROPN
fnp-3528	923	4	s.	s.	PROPN
fnp-3528	923	5	;	;	PUNCT
fnp-3528	923	6	weickert	weickert	PROPN
fnp-3528	923	7	,	,	PUNCT
fnp-3528	923	8	c.	c.	PROPN
fnp-3528	923	9	s.	s.	PROPN
fnp-3528	923	10	;	;	PUNCT
fnp-3528	923	11	garner	garner	PROPN
fnp-3528	923	12	,	,	PUNCT
fnp-3528	923	13	b.	b.	PROPN
fnp-3528	923	14	role	role	NOUN
fnp-3528	923	15	of	of	ADP
fnp-3528	923	16	atp	atp	NOUN
fnp-3528	923	17	-	-	PUNCT
fnp-3528	923	18	binding	bind	VERB
fnp-3528	923	19	cassette	cassette	NOUN
fnp-3528	923	20	transporters	transporter	NOUN
fnp-3528	923	21	in	in	ADP
fnp-3528	923	22	brain	brain	NOUN
fnp-3528	923	23	lipid	lipid	NOUN
fnp-3528	923	24	transport	transport	NOUN
fnp-3528	923	25	and	and	CCONJ
fnp-3528	923	26	neurological	neurological	ADJ
fnp-3528	923	27	disease	disease	NOUN
fnp-3528	923	28	.	.	PUNCT
fnp-3528	924	1	j	j	PROPN
fnp-3528	924	2	neurochem	neurochem	PROPN
fnp-3528	924	3	2008	2008	NUM
fnp-3528	924	4	,	,	PUNCT
fnp-3528	924	5	104	104	NUM
fnp-3528	924	6	,	,	PUNCT
fnp-3528	924	7	1145	1145	NUM
fnp-3528	924	8	-	-	SYM
fnp-3528	924	9	66	66	NUM
fnp-3528	924	10	.	.	PUNCT
fnp-3528	925	1	sato	sato	PROPN
fnp-3528	925	2	,	,	PUNCT
fnp-3528	925	3	k.	k.	PROPN
fnp-3528	925	4	;	;	PUNCT
fnp-3528	925	5	malchinkhuu	malchinkhuu	PROPN
fnp-3528	925	6	,	,	PUNCT
fnp-3528	925	7	e.	e.	PROPN
fnp-3528	925	8	;	;	PUNCT
fnp-3528	925	9	horiuchi	horiuchi	PROPN
fnp-3528	925	10	,	,	PUNCT
fnp-3528	925	11	y.	y.	PROPN
fnp-3528	925	12	;	;	PUNCT
fnp-3528	925	13	mogi	mogi	PROPN
fnp-3528	925	14	,	,	PUNCT
fnp-3528	925	15	c.	c.	PROPN
fnp-3528	925	16	;	;	PUNCT
fnp-3528	925	17	tomura	tomura	ADJ
fnp-3528	925	18	,	,	PUNCT
fnp-3528	925	19	h.	h.	PROPN
fnp-3528	925	20	;	;	PUNCT
fnp-3528	925	21	tosaka	tosaka	ADV
fnp-3528	925	22	,	,	PUNCT
fnp-3528	925	23	m.	m.	NOUN
fnp-3528	925	24	;	;	PUNCT
fnp-3528	925	25	yoshimoto	yoshimoto	NOUN
fnp-3528	925	26	,	,	PUNCT
fnp-3528	925	27	y.	y.	PROPN
fnp-3528	925	28	;	;	PUNCT
fnp-3528	925	29	kuwabara	kuwabara	PROPN
fnp-3528	925	30	,	,	PUNCT
fnp-3528	925	31	a.	a.	NOUN
fnp-3528	925	32	;	;	PUNCT
fnp-3528	925	33	okajima	okajima	PROPN
fnp-3528	925	34	,	,	PUNCT
fnp-3528	925	35	f.	f.	PROPN
fnp-3528	925	36	critical	critical	ADJ
fnp-3528	925	37	role	role	NOUN
fnp-3528	925	38	of	of	ADP
fnp-3528	925	39	abca1	abca1	NOUN
fnp-3528	925	40	transporter	transporter	NOUN
fnp-3528	925	41	in	in	ADP
fnp-3528	925	42	sphingosine	sphingosine	NOUN
fnp-3528	925	43	1	1	NUM
fnp-3528	925	44	-	-	PUNCT
fnp-3528	925	45	phosphate	phosphate	NOUN
fnp-3528	925	46	release	release	NOUN
fnp-3528	925	47	from	from	ADP
fnp-3528	925	48	astrocytes	astrocyte	NOUN
fnp-3528	925	49	.	.	PUNCT
fnp-3528	926	1	j	j	PROPN
fnp-3528	926	2	neurochem	neurochem	ADV
fnp-3528	926	3	2007	2007	NUM
fnp-3528	926	4	,	,	PUNCT
fnp-3528	926	5	103	103	NUM
fnp-3528	926	6	,	,	PUNCT
fnp-3528	926	7	2610	2610	NUM
fnp-3528	926	8	-	-	SYM
fnp-3528	926	9	9	9	NUM
fnp-3528	926	10	.	.	PUNCT
fnp-3528	927	1	zhao	zhao	NOUN
fnp-3528	927	2	,	,	PUNCT
fnp-3528	927	3	x.	x.	NOUN
fnp-3528	927	4	;	;	PUNCT
fnp-3528	927	5	murata	murata	PROPN
fnp-3528	927	6	,	,	PUNCT
fnp-3528	927	7	t.	t.	PROPN
fnp-3528	927	8	;	;	PUNCT
fnp-3528	927	9	ohno	ohno	PROPN
fnp-3528	927	10	,	,	PUNCT
fnp-3528	927	11	s.	s.	PROPN
fnp-3528	927	12	;	;	PUNCT
fnp-3528	927	13	day	day	NOUN
fnp-3528	927	14	,	,	PUNCT
fnp-3528	927	15	n.	n.	NOUN
fnp-3528	927	16	;	;	PUNCT
fnp-3528	927	17	song	song	PROPN
fnp-3528	927	18	,	,	PUNCT
fnp-3528	927	19	j.	j.	PROPN
fnp-3528	927	20	;	;	PUNCT
fnp-3528	927	21	nomura	nomura	NOUN
fnp-3528	927	22	,	,	PUNCT
fnp-3528	927	23	n.	n.	NOUN
fnp-3528	927	24	;	;	PUNCT
fnp-3528	927	25	nakahara	nakahara	ADJ
fnp-3528	927	26	,	,	PUNCT
fnp-3528	927	27	t.	t.	PROPN
fnp-3528	927	28	;	;	PUNCT
fnp-3528	927	29	yokoyama	yokoyama	PROPN
fnp-3528	927	30	,	,	PUNCT
fnp-3528	927	31	k.	k.	PROPN
fnp-3528	927	32	k.	k.	PROPN
fnp-3528	928	1	protein	protein	PROPN
fnp-3528	928	2	kinase	kinase	PROPN
fnp-3528	928	3	calpha	calpha	PROPN
fnp-3528	928	4	plays	play	VERB
fnp-3528	928	5	a	a	DET
fnp-3528	928	6	critical	critical	ADJ
fnp-3528	928	7	role	role	NOUN
fnp-3528	928	8	in	in	ADP
fnp-3528	928	9	mannosylerythritol	mannosylerythritol	NOUN
fnp-3528	928	10	lipid	lipid	NOUN
fnp-3528	928	11	-	-	PUNCT
fnp-3528	928	12	induced	induce	VERB
fnp-3528	928	13	differentiation	differentiation	NOUN
fnp-3528	928	14	of	of	ADP
fnp-3528	928	15	melanoma	melanoma	ADJ
fnp-3528	928	16	b16	b16	NOUN
fnp-3528	928	17	cells	cell	NOUN
fnp-3528	928	18	.	.	PUNCT
fnp-3528	929	1	j	j	PROPN
fnp-3528	929	2	biol	biol	PROPN
fnp-3528	929	3	chem	chem	NOUN
fnp-3528	929	4	2001	2001	NUM
fnp-3528	929	5	,	,	PUNCT
fnp-3528	929	6	276	276	NUM
fnp-3528	929	7	,	,	PUNCT
fnp-3528	929	8	39903	39903	NUM
fnp-3528	929	9	-	-	SYM
fnp-3528	929	10	10	10	NUM
fnp-3528	929	11	.	.	PUNCT
fnp-3528	930	1	olivier	olivier	NOUN
fnp-3528	930	2	,	,	PUNCT
fnp-3528	930	3	m.	m.	NOUN
fnp-3528	930	4	;	;	PUNCT
fnp-3528	930	5	bott	bott	PROPN
fnp-3528	930	6	,	,	PUNCT
fnp-3528	930	7	g.	g.	PROPN
fnp-3528	930	8	r.	r.	PROPN
fnp-3528	930	9	;	;	PUNCT
fnp-3528	930	10	frisdal	frisdal	PROPN
fnp-3528	930	11	,	,	PUNCT
fnp-3528	930	12	e.	e.	PROPN
fnp-3528	930	13	;	;	PUNCT
fnp-3528	930	14	nowick	nowick	ADJ
fnp-3528	930	15	,	,	PUNCT
fnp-3528	930	16	m.	m.	NOUN
fnp-3528	930	17	;	;	PUNCT
fnp-3528	930	18	plengpanich	plengpanich	PROPN
fnp-3528	930	19	,	,	PUNCT
fnp-3528	930	20	w.	w.	PROPN
fnp-3528	930	21	;	;	PUNCT
fnp-3528	930	22	desmarchelier	desmarchelier	NOUN
fnp-3528	930	23	,	,	PUNCT
fnp-3528	930	24	c.	c.	PROPN
fnp-3528	930	25	;	;	PUNCT
fnp-3528	930	26	roi	roi	PROPN
fnp-3528	930	27	,	,	PUNCT
fnp-3528	930	28	s.	s.	PROPN
fnp-3528	930	29	;	;	PUNCT
fnp-3528	930	30	quinn	quinn	PROPN
fnp-3528	930	31	,	,	PUNCT
fnp-3528	930	32	c.	c.	PROPN
fnp-3528	930	33	m.	m.	NOUN
fnp-3528	930	34	;	;	PUNCT
fnp-3528	930	35	gelissen	gelissen	PROPN
fnp-3528	930	36	,	,	PUNCT
fnp-3528	930	37	i.	i.	NOUN
fnp-3528	930	38	;	;	PUNCT
fnp-3528	930	39	jessup	jessup	PROPN
fnp-3528	930	40	,	,	PUNCT
fnp-3528	930	41	w.	w.	PROPN
fnp-3528	930	42	;	;	PUNCT
fnp-3528	930	43	van	van	PROPN
fnp-3528	930	44	eck	eck	PROPN
fnp-3528	930	45	,	,	PUNCT
fnp-3528	930	46	m.	m.	NOUN
fnp-3528	930	47	;	;	PUNCT
fnp-3528	930	48	guerin	guerin	PROPN
fnp-3528	930	49	,	,	PUNCT
fnp-3528	930	50	m.	m.	NOUN
fnp-3528	930	51	;	;	PUNCT
fnp-3528	930	52	le	le	PROPN
fnp-3528	930	53	goff	goff	PROPN
fnp-3528	930	54	,	,	PUNCT
fnp-3528	930	55	w.	w.	PROPN
fnp-3528	930	56	;	;	PUNCT
fnp-3528	930	57	reboul	reboul	PROPN
fnp-3528	930	58	,	,	PUNCT
fnp-3528	930	59	e.	e.	PROPN
fnp-3528	930	60	abcg1	abcg1	PROPN
fnp-3528	930	61	is	be	AUX
fnp-3528	930	62	involved	involve	VERB
fnp-3528	930	63	in	in	ADP
fnp-3528	930	64	vitamin	vitamin	NOUN
fnp-3528	930	65	e	e	NOUN
fnp-3528	930	66	efflux	efflux	NOUN
fnp-3528	930	67	.	.	PUNCT
fnp-3528	931	1	biochim	biochim	PROPN
fnp-3528	931	2	biophys	biophy	NOUN
fnp-3528	931	3	acta	acta	PROPN
fnp-3528	931	4	2014	2014	NUM
fnp-3528	931	5	,	,	PUNCT
fnp-3528	931	6	1841	1841	NUM
fnp-3528	931	7	,	,	PUNCT
fnp-3528	931	8	1741	1741	NUM
fnp-3528	931	9	-	-	SYM
fnp-3528	931	10	51	51	NUM
fnp-3528	931	11	.	.	PUNCT
fnp-3528	932	1	stefan	stefan	PROPN
fnp-3528	932	2	,	,	PUNCT
fnp-3528	932	3	s.	s.	PROPN
fnp-3528	932	4	m.	m.	PROPN
fnp-3528	932	5	;	;	PUNCT
fnp-3528	932	6	jansson	jansson	PROPN
fnp-3528	932	7	,	,	PUNCT
fnp-3528	932	8	p.	p.	PROPN
fnp-3528	932	9	j.	j.	PROPN
fnp-3528	932	10	;	;	PUNCT
fnp-3528	932	11	kalinowski	kalinowski	PROPN
fnp-3528	932	12	,	,	PUNCT
fnp-3528	932	13	d.	d.	PROPN
fnp-3528	932	14	s.	s.	PROPN
fnp-3528	932	15	;	;	PUNCT
fnp-3528	932	16	anjum	anjum	PROPN
fnp-3528	932	17	,	,	PUNCT
fnp-3528	932	18	r.	r.	PROPN
fnp-3528	932	19	;	;	PUNCT
fnp-3528	932	20	dharmasivam	dharmasivam	NOUN
fnp-3528	932	21	,	,	PUNCT
fnp-3528	932	22	m.	m.	NOUN
fnp-3528	932	23	;	;	PUNCT
fnp-3528	932	24	richardson	richardson	PROPN
fnp-3528	932	25	,	,	PUNCT
fnp-3528	932	26	d.	d.	PROPN
fnp-3528	932	27	r.	r.	PROPN
fnp-3528	932	28	the	the	DET
fnp-3528	932	29	growing	grow	VERB
fnp-3528	932	30	evidence	evidence	NOUN
fnp-3528	932	31	for	for	ADP
fnp-3528	932	32	targeting	target	VERB
fnp-3528	932	33	p	p	NOUN
fnp-3528	932	34	-	-	PUNCT
fnp-3528	932	35	glycoprotein	glycoprotein	NOUN
fnp-3528	932	36	in	in	ADP
fnp-3528	932	37	lysosomes	lysosome	NOUN
fnp-3528	932	38	to	to	PART
fnp-3528	932	39	overcome	overcome	VERB
fnp-3528	932	40	resistance	resistance	NOUN
fnp-3528	932	41	.	.	PUNCT
fnp-3528	933	1	future	future	ADJ
fnp-3528	933	2	med	med	ADJ
fnp-3528	933	3	chem	chem	NOUN
fnp-3528	933	4	2020	2020	NUM
fnp-3528	933	5	,	,	PUNCT
fnp-3528	933	6	12	12	NUM
fnp-3528	933	7	,	,	PUNCT
fnp-3528	933	8	473	473	NUM
fnp-3528	933	9	-	-	SYM
fnp-3528	933	10	477	477	NUM
fnp-3528	933	11	.	.	PUNCT
fnp-3528	934	1	zhitomirsky	zhitomirsky	PROPN
fnp-3528	934	2	,	,	PUNCT
fnp-3528	934	3	b.	b.	PROPN
fnp-3528	934	4	;	;	PUNCT
fnp-3528	934	5	assaraf	assaraf	NOUN
fnp-3528	934	6	,	,	PUNCT
fnp-3528	934	7	y.	y.	PROPN
fnp-3528	934	8	g.	g.	PROPN
fnp-3528	934	9	lysosomes	lysosomes	PROPN
fnp-3528	934	10	as	as	ADP
fnp-3528	934	11	mediators	mediator	NOUN
fnp-3528	934	12	of	of	ADP
fnp-3528	934	13	drug	drug	NOUN
fnp-3528	934	14	resistance	resistance	NOUN
fnp-3528	934	15	in	in	ADP
fnp-3528	934	16	cancer	cancer	NOUN
fnp-3528	934	17	.	.	PUNCT
fnp-3528	935	1	drug	drug	NOUN
fnp-3528	935	2	resist	resist	VERB
fnp-3528	935	3	updat	updat	PROPN
fnp-3528	935	4	2016	2016	NUM
fnp-3528	935	5	,	,	PUNCT
fnp-3528	935	6	24	24	NUM
fnp-3528	935	7	,	,	PUNCT
fnp-3528	935	8	23	23	NUM
fnp-3528	935	9	-	-	SYM
fnp-3528	935	10	33	33	NUM
fnp-3528	935	11	.	.	PUNCT
fnp-3528	936	1	chapuy	chapuy	NOUN
fnp-3528	936	2	,	,	PUNCT
fnp-3528	936	3	b.	b.	PROPN
fnp-3528	936	4	;	;	PUNCT
fnp-3528	936	5	panse	panse	NOUN
fnp-3528	936	6	,	,	PUNCT
fnp-3528	936	7	m.	m.	NOUN
fnp-3528	936	8	;	;	PUNCT
fnp-3528	936	9	radunski	radunski	PROPN
fnp-3528	936	10	,	,	PUNCT
fnp-3528	936	11	u.	u.	PROPN
fnp-3528	936	12	;	;	PUNCT
fnp-3528	936	13	koch	koch	PROPN
fnp-3528	936	14	,	,	PUNCT
fnp-3528	936	15	r.	r.	PROPN
fnp-3528	936	16	;	;	PUNCT
fnp-3528	936	17	wenzel	wenzel	PROPN
fnp-3528	936	18	,	,	PUNCT
fnp-3528	936	19	d.	d.	PROPN
fnp-3528	936	20	;	;	PUNCT
fnp-3528	936	21	inagaki	inagaki	PROPN
fnp-3528	936	22	,	,	PUNCT
fnp-3528	936	23	n.	n.	NOUN
fnp-3528	936	24	;	;	PUNCT
fnp-3528	936	25	haase	haase	PROPN
fnp-3528	936	26	,	,	PUNCT
fnp-3528	936	27	d.	d.	PROPN
fnp-3528	936	28	;	;	PUNCT
fnp-3528	936	29	truemper	truemper	PROPN
fnp-3528	936	30	,	,	PUNCT
fnp-3528	936	31	l.	l.	PROPN
fnp-3528	936	32	;	;	PUNCT
fnp-3528	936	33	wulf	wulf	PROPN
fnp-3528	936	34	,	,	PUNCT
fnp-3528	937	1	g.	g.	PROPN
fnp-3528	937	2	g.	g.	PROPN
fnp-3528	937	3	abc	abc	PROPN
fnp-3528	937	4	transporter	transporter	NOUN
fnp-3528	937	5	a3	a3	NOUN
fnp-3528	937	6	facilitates	facilitate	VERB
fnp-3528	937	7	lysosomal	lysosomal	ADJ
fnp-3528	937	8	sequestration	sequestration	NOUN
fnp-3528	937	9	of	of	ADP
fnp-3528	937	10	imatinib	imatinib	NOUN
fnp-3528	937	11	and	and	CCONJ
fnp-3528	937	12	modulates	modulate	VERB
fnp-3528	937	13	susceptibility	susceptibility	NOUN
fnp-3528	937	14	of	of	ADP
fnp-3528	937	15	chronic	chronic	ADJ
fnp-3528	937	16	myeloid	myeloid	NOUN
fnp-3528	937	17	leukemia	leukemia	NOUN
fnp-3528	937	18	cell	cell	NOUN
fnp-3528	937	19	lines	line	NOUN
fnp-3528	937	20	to	to	ADP
fnp-3528	937	21	this	this	DET
fnp-3528	937	22	drug	drug	NOUN
fnp-3528	937	23	.	.	PUNCT
fnp-3528	938	1	haematol	haematol	NOUN
fnp-3528	938	2	2009	2009	NUM
fnp-3528	938	3	,	,	PUNCT
fnp-3528	938	4	94	94	NUM
fnp-3528	938	5	,	,	PUNCT
fnp-3528	938	6	1528	1528	NUM
fnp-3528	938	7	-	-	SYM
fnp-3528	938	8	36	36	NUM
fnp-3528	938	9	.	.	PUNCT
fnp-3528	939	1	chapuy	chapuy	NOUN
fnp-3528	939	2	,	,	PUNCT
fnp-3528	939	3	b.	b.	PROPN
fnp-3528	939	4	;	;	PUNCT
fnp-3528	939	5	koch	koch	PROPN
fnp-3528	939	6	,	,	PUNCT
fnp-3528	939	7	r.	r.	PROPN
fnp-3528	939	8	;	;	PUNCT
fnp-3528	939	9	radunski	radunski	PROPN
fnp-3528	939	10	,	,	PUNCT
fnp-3528	939	11	u.	u.	PROPN
fnp-3528	939	12	;	;	PUNCT
fnp-3528	939	13	corsham	corsham	PROPN
fnp-3528	939	14	,	,	PUNCT
fnp-3528	939	15	s.	s.	PROPN
fnp-3528	939	16	;	;	PUNCT
fnp-3528	940	1	cheong	cheong	PROPN
fnp-3528	940	2	,	,	PUNCT
fnp-3528	940	3	n.	n.	PROPN
fnp-3528	940	4	;	;	PUNCT
fnp-3528	940	5	inagaki	inagaki	PROPN
fnp-3528	940	6	,	,	PUNCT
fnp-3528	940	7	n.	n.	NOUN
fnp-3528	940	8	;	;	PUNCT
fnp-3528	940	9	ban	ban	NOUN
fnp-3528	940	10	,	,	PUNCT
fnp-3528	940	11	n.	n.	NOUN
fnp-3528	940	12	;	;	PUNCT
fnp-3528	940	13	wenzel	wenzel	PROPN
fnp-3528	940	14	,	,	PUNCT
fnp-3528	940	15	d.	d.	PROPN
fnp-3528	940	16	;	;	PUNCT
fnp-3528	940	17	reinhardt	reinhardt	PROPN
fnp-3528	940	18	,	,	PUNCT
fnp-3528	940	19	d.	d.	PROPN
fnp-3528	940	20	;	;	PUNCT
fnp-3528	940	21	zapf	zapf	NOUN
fnp-3528	940	22	,	,	PUNCT
fnp-3528	940	23	a.	a.	NOUN
fnp-3528	940	24	;	;	PUNCT
fnp-3528	940	25	schweyer	schweyer	NOUN
fnp-3528	940	26	,	,	PUNCT
fnp-3528	940	27	s.	s.	PROPN
fnp-3528	940	28	;	;	PUNCT
fnp-3528	940	29	kosari	kosari	X
fnp-3528	940	30	,	,	PUNCT
fnp-3528	940	31	f.	f.	PROPN
fnp-3528	940	32	;	;	PUNCT
fnp-3528	940	33	klapper	klapper	PROPN
fnp-3528	940	34	,	,	PUNCT
fnp-3528	940	35	w.	w.	PROPN
fnp-3528	940	36	;	;	PUNCT
fnp-3528	940	37	truemper	truemper	PROPN
fnp-3528	940	38	,	,	PUNCT
fnp-3528	940	39	l.	l.	PROPN
fnp-3528	940	40	;	;	PUNCT
fnp-3528	940	41	wulf	wulf	PROPN
fnp-3528	940	42	,	,	PUNCT
fnp-3528	940	43	g.	g.	PROPN
fnp-3528	940	44	g.	g.	PROPN
fnp-3528	940	45	intracellular	intracellular	PROPN
fnp-3528	940	46	abc	abc	PROPN
fnp-3528	940	47	transporter	transporter	NOUN
fnp-3528	940	48	a3	a3	NOUN
fnp-3528	940	49	confers	confer	NOUN
fnp-3528	940	50	multidrug	multidrug	VERB
fnp-3528	940	51	resistance	resistance	NOUN
fnp-3528	940	52	in	in	ADP
fnp-3528	940	53	leukemia	leukemia	NOUN
fnp-3528	940	54	cells	cell	NOUN
fnp-3528	940	55	by	by	ADP
fnp-3528	940	56	lysosomal	lysosomal	ADJ
fnp-3528	940	57	drug	drug	NOUN
fnp-3528	940	58	sequestration	sequestration	NOUN
fnp-3528	940	59	.	.	PUNCT
fnp-3528	941	1	leuk	leuk	PROPN
fnp-3528	941	2	2008	2008	NUM
fnp-3528	941	3	,	,	PUNCT
fnp-3528	941	4	22	22	NUM
fnp-3528	941	5	,	,	PUNCT
fnp-3528	941	6	1576	1576	NUM
fnp-3528	941	7	-	-	SYM
fnp-3528	941	8	86	86	NUM
fnp-3528	941	9	.	.	PUNCT
fnp-3528	942	1	dharmapuri	dharmapuri	PROPN
fnp-3528	942	2	,	,	PUNCT
fnp-3528	942	3	g.	g.	PROPN
fnp-3528	942	4	;	;	PUNCT
fnp-3528	942	5	doneti	doneti	PROPN
fnp-3528	942	6	,	,	PUNCT
fnp-3528	942	7	r.	r.	PROPN
fnp-3528	942	8	;	;	PUNCT
fnp-3528	942	9	philip	philip	PROPN
fnp-3528	942	10	,	,	PUNCT
fnp-3528	942	11	g.	g.	PROPN
fnp-3528	942	12	h.	h.	PROPN
fnp-3528	942	13	;	;	PUNCT
fnp-3528	942	14	kalle	kalle	X
fnp-3528	942	15	,	,	PUNCT
fnp-3528	942	16	a.	a.	PROPN
fnp-3528	942	17	m.	m.	NOUN
fnp-3528	942	18	celecoxib	celecoxib	NOUN
fnp-3528	942	19	sensitizes	sensitize	VERB
fnp-3528	942	20	imatinib	imatinib	NOUN
fnp-3528	942	21	-	-	PUNCT
fnp-3528	942	22	resistant	resistant	ADJ
fnp-3528	942	23	k562	k562	PROPN
fnp-3528	942	24	cells	cell	NOUN
fnp-3528	942	25	to	to	ADP
fnp-3528	942	26	imatinib	imatinib	NOUN
fnp-3528	942	27	by	by	ADP
fnp-3528	942	28	inhibiting	inhibit	VERB
fnp-3528	942	29	mrp1	mrp1	NOUN
fnp-3528	942	30	-	-	PUNCT
fnp-3528	942	31	5	5	NUM
fnp-3528	942	32	,	,	PUNCT
fnp-3528	942	33	abca2	abca2	NOUN
fnp-3528	942	34	and	and	CCONJ
fnp-3528	942	35	abcg2	abcg2	NOUN
fnp-3528	942	36	transporters	transporter	NOUN
fnp-3528	942	37	via	via	ADP
fnp-3528	942	38	wnt	wnt	NOUN
fnp-3528	942	39	and	and	CCONJ
fnp-3528	942	40	ras	ras	X
fnp-3528	942	41	signaling	signal	VERB
fnp-3528	942	42	pathways	pathway	NOUN
fnp-3528	942	43	.	.	PUNCT
fnp-3528	943	1	leuk	leuk	PROPN
fnp-3528	943	2	res	re	NOUN
fnp-3528	943	3	2015	2015	NUM
fnp-3528	943	4	,	,	PUNCT
fnp-3528	943	5	39	39	NUM
fnp-3528	943	6	,	,	PUNCT
fnp-3528	943	7	696	696	NUM
fnp-3528	943	8	-	-	SYM
fnp-3528	943	9	701	701	NUM
fnp-3528	943	10	.	.	PUNCT
fnp-3528	944	1	steinbach	steinbach	PROPN
fnp-3528	944	2	,	,	PUNCT
fnp-3528	944	3	d.	d.	PROPN
fnp-3528	944	4	;	;	PUNCT
fnp-3528	944	5	gillet	gillet	PROPN
fnp-3528	944	6	,	,	PUNCT
fnp-3528	944	7	j.	j.	PROPN
fnp-3528	944	8	p.	p.	PROPN
fnp-3528	944	9	;	;	PUNCT
fnp-3528	944	10	sauerbrey	sauerbrey	PROPN
fnp-3528	944	11	,	,	PUNCT
fnp-3528	944	12	a.	a.	NOUN
fnp-3528	944	13	;	;	PUNCT
fnp-3528	944	14	gruhn	gruhn	PROPN
fnp-3528	944	15	,	,	PUNCT
fnp-3528	944	16	b.	b.	PROPN
fnp-3528	944	17	;	;	PUNCT
fnp-3528	944	18	dawczynski	dawczynski	PROPN
fnp-3528	944	19	,	,	PUNCT
fnp-3528	944	20	k.	k.	PROPN
fnp-3528	944	21	;	;	PUNCT
fnp-3528	944	22	bertholet	bertholet	VERB
fnp-3528	944	23	,	,	PUNCT
fnp-3528	944	24	v.	v.	ADV
fnp-3528	944	25	;	;	PUNCT
fnp-3528	944	26	de	de	X
fnp-3528	944	27	longueville	longueville	PROPN
fnp-3528	944	28	,	,	PUNCT
fnp-3528	944	29	f.	f.	PROPN
fnp-3528	944	30	;	;	PUNCT
fnp-3528	944	31	zintl	zintl	PROPN
fnp-3528	944	32	,	,	PUNCT
fnp-3528	944	33	f.	f.	PROPN
fnp-3528	944	34	;	;	PUNCT
fnp-3528	944	35	remacle	remacle	PROPN
fnp-3528	944	36	,	,	PUNCT
fnp-3528	944	37	j.	j.	PROPN
fnp-3528	944	38	;	;	PUNCT
fnp-3528	944	39	efferth	efferth	ADJ
fnp-3528	944	40	,	,	PUNCT
fnp-3528	944	41	t.	t.	PROPN
fnp-3528	944	42	abca3	abca3	PROPN
fnp-3528	944	43	as	as	ADP
fnp-3528	944	44	a	a	DET
fnp-3528	944	45	possible	possible	ADJ
fnp-3528	944	46	cause	cause	NOUN
fnp-3528	944	47	of	of	ADP
fnp-3528	944	48	drug	drug	NOUN
fnp-3528	944	49	resistance	resistance	NOUN
fnp-3528	944	50	in	in	ADP
fnp-3528	944	51	childhood	childhood	PROPN
fnp-3528	944	52	acute	acute	NOUN
fnp-3528	944	53	myeloid	myeloid	NOUN
fnp-3528	944	54	leukemia	leukemia	NOUN
fnp-3528	944	55	.	.	PUNCT
fnp-3528	945	1	clin	clin	PROPN
fnp-3528	945	2	cancer	cancer	NOUN
fnp-3528	945	3	res	re	NOUN
fnp-3528	945	4	2006	2006	NUM
fnp-3528	945	5	,	,	PUNCT
fnp-3528	945	6	12	12	NUM
fnp-3528	945	7	,	,	PUNCT
fnp-3528	945	8	4357	4357	NUM
fnp-3528	945	9	-	-	SYM
fnp-3528	945	10	63	63	NUM
fnp-3528	945	11	.	.	PUNCT
fnp-3528	946	1	laing	laing	PROPN
fnp-3528	946	2	,	,	PUNCT
fnp-3528	946	3	n.	n.	PROPN
fnp-3528	946	4	m.	m.	NOUN
fnp-3528	946	5	;	;	PUNCT
fnp-3528	946	6	belinsky	belinsky	NOUN
fnp-3528	946	7	,	,	PUNCT
fnp-3528	946	8	m.	m.	NOUN
fnp-3528	946	9	g.	g.	PROPN
fnp-3528	946	10	;	;	PUNCT
fnp-3528	946	11	kruh	kruh	PROPN
fnp-3528	946	12	,	,	PUNCT
fnp-3528	946	13	g.	g.	PROPN
fnp-3528	946	14	d.	d.	PROPN
fnp-3528	946	15	;	;	PUNCT
fnp-3528	946	16	bell	bell	PROPN
fnp-3528	946	17	,	,	PUNCT
fnp-3528	946	18	d.	d.	PROPN
fnp-3528	946	19	w.	w.	PROPN
fnp-3528	946	20	;	;	PUNCT
fnp-3528	946	21	boyd	boyd	PROPN
fnp-3528	946	22	,	,	PUNCT
fnp-3528	946	23	j.	j.	PROPN
fnp-3528	946	24	t.	t.	PROPN
fnp-3528	946	25	;	;	PUNCT
fnp-3528	946	26	barone	barone	PROPN
fnp-3528	946	27	,	,	PUNCT
fnp-3528	946	28	l.	l.	PROPN
fnp-3528	946	29	;	;	PUNCT
fnp-3528	946	30	testa	testa	PROPN
fnp-3528	946	31	,	,	PUNCT
fnp-3528	946	32	j.	j.	PROPN
fnp-3528	946	33	r.	r.	PROPN
fnp-3528	946	34	;	;	PUNCT
fnp-3528	946	35	tew	tew	PROPN
fnp-3528	946	36	,	,	PUNCT
fnp-3528	946	37	k.	k.	PROPN
fnp-3528	946	38	d.	d.	PROPN
fnp-3528	946	39	amplification	amplification	NOUN
fnp-3528	946	40	of	of	ADP
fnp-3528	946	41	the	the	DET
fnp-3528	946	42	atp	atp	NOUN
fnp-3528	946	43	-	-	PUNCT
fnp-3528	946	44	binding	bind	VERB
fnp-3528	946	45	cassette	cassette	NOUN
fnp-3528	946	46	2	2	NUM
fnp-3528	946	47	transporter	transporter	NOUN
fnp-3528	946	48	gene	gene	NOUN
fnp-3528	946	49	is	be	AUX
fnp-3528	946	50	functionally	functionally	ADV
fnp-3528	946	51	linked	link	VERB
fnp-3528	946	52	with	with	ADP
fnp-3528	946	53	enhanced	enhanced	ADJ
fnp-3528	946	54	efflux	efflux	NOUN
fnp-3528	946	55	of	of	ADP
fnp-3528	946	56	estramustine	estramustine	NOUN
fnp-3528	946	57	in	in	ADP
fnp-3528	946	58	ovarian	ovarian	ADJ
fnp-3528	946	59	carcinoma	carcinoma	NOUN
fnp-3528	946	60	cells	cell	NOUN
fnp-3528	946	61	.	.	PUNCT
fnp-3528	947	1	cancer	cancer	NOUN
fnp-3528	947	2	res	re	NOUN
fnp-3528	947	3	1998	1998	NUM
fnp-3528	947	4	,	,	PUNCT
fnp-3528	947	5	58	58	NUM
fnp-3528	947	6	,	,	PUNCT
fnp-3528	947	7	1332	1332	NUM
fnp-3528	947	8	-	-	SYM
fnp-3528	947	9	7	7	NUM
fnp-3528	947	10	.	.	X
fnp-3528	947	11	mack	mack	PROPN
fnp-3528	947	12	,	,	PUNCT
fnp-3528	947	13	j.	j.	PROPN
fnp-3528	947	14	t.	t.	PROPN
fnp-3528	947	15	;	;	PUNCT
fnp-3528	947	16	brown	brown	PROPN
fnp-3528	947	17	,	,	PUNCT
fnp-3528	947	18	c.	c.	PROPN
fnp-3528	947	19	b.	b.	PROPN
fnp-3528	947	20	;	;	PUNCT
fnp-3528	947	21	garrett	garrett	PROPN
fnp-3528	947	22	,	,	PUNCT
fnp-3528	947	23	t.	t.	PROPN
fnp-3528	947	24	e.	e.	PROPN
fnp-3528	947	25	;	;	PUNCT
fnp-3528	947	26	uys	uys	PROPN
fnp-3528	947	27	,	,	PUNCT
fnp-3528	947	28	j.	j.	PROPN
fnp-3528	947	29	d.	d.	PROPN
fnp-3528	947	30	;	;	PUNCT
fnp-3528	947	31	townsend	townsend	PROPN
fnp-3528	947	32	,	,	PUNCT
fnp-3528	947	33	d.	d.	PROPN
fnp-3528	947	34	m.	m.	PROPN
fnp-3528	947	35	;	;	PUNCT
fnp-3528	947	36	tew	tew	PROPN
fnp-3528	947	37	,	,	PUNCT
fnp-3528	947	38	k.	k.	PROPN
fnp-3528	947	39	d.	d.	PROPN
fnp-3528	947	40	ablation	ablation	NOUN
fnp-3528	947	41	of	of	ADP
fnp-3528	947	42	the	the	DET
fnp-3528	947	43	atp	atp	NOUN
fnp-3528	947	44	-	-	PUNCT
fnp-3528	947	45	binding	bind	VERB
fnp-3528	947	46	cassette	cassette	NOUN
fnp-3528	947	47	transporter	transporter	NOUN
fnp-3528	947	48	,	,	PUNCT
fnp-3528	947	49	abca2	abca2	NOUN
fnp-3528	947	50	modifies	modify	VERB
fnp-3528	947	51	response	response	NOUN
fnp-3528	947	52	to	to	ADP
fnp-3528	947	53	estrogen	estrogen	NOUN
fnp-3528	947	54	-	-	PUNCT
fnp-3528	947	55	based	base	VERB
fnp-3528	947	56	therapies	therapy	NOUN
fnp-3528	947	57	.	.	PUNCT
fnp-3528	948	1	biomed	biome	VERB
fnp-3528	948	2	pharmacother	pharmacother	ADJ
fnp-3528	948	3	2012	2012	NUM
fnp-3528	948	4	,	,	PUNCT
fnp-3528	948	5	66	66	NUM
fnp-3528	948	6	,	,	PUNCT
fnp-3528	948	7	403	403	NUM
fnp-3528	948	8	-	-	SYM
fnp-3528	948	9	8	8	NUM
fnp-3528	948	10	.	.	PUNCT
fnp-3528	949	1	dohmen	dohman	NOUN
fnp-3528	949	2	,	,	PUNCT
fnp-3528	949	3	l.	l.	PROPN
fnp-3528	949	4	c.	c.	PROPN
fnp-3528	949	5	;	;	PUNCT
fnp-3528	949	6	navas	navas	PROPN
fnp-3528	949	7	,	,	PUNCT
fnp-3528	949	8	a.	a.	NOUN
fnp-3528	949	9	;	;	PUNCT
fnp-3528	949	10	vargas	vargas	PROPN
fnp-3528	949	11	,	,	PUNCT
fnp-3528	949	12	d.	d.	PROPN
fnp-3528	949	13	a.	a.	PROPN
fnp-3528	949	14	;	;	PUNCT
fnp-3528	949	15	gregory	gregory	PROPN
fnp-3528	949	16	,	,	PUNCT
fnp-3528	949	17	d.	d.	PROPN
fnp-3528	949	18	j.	j.	PROPN
fnp-3528	949	19	;	;	PUNCT
fnp-3528	949	20	kip	kip	PROPN
fnp-3528	949	21	,	,	PUNCT
fnp-3528	949	22	a.	a.	NOUN
fnp-3528	949	23	;	;	PUNCT
fnp-3528	949	24	dorlo	dorlo	NOUN
fnp-3528	949	25	,	,	PUNCT
fnp-3528	949	26	t.	t.	PROPN
fnp-3528	949	27	p.	p.	PROPN
fnp-3528	949	28	;	;	PUNCT
fnp-3528	949	29	gomez	gomez	PROPN
fnp-3528	949	30	,	,	PUNCT
fnp-3528	949	31	m.	m.	NOUN
fnp-3528	949	32	a.	a.	NOUN
fnp-3528	949	33	functional	functional	PROPN
fnp-3528	949	34	validation	validation	NOUN
fnp-3528	949	35	of	of	ADP
fnp-3528	949	36	abca3	abca3	PROPN
fnp-3528	949	37	as	as	ADP
fnp-3528	949	38	a	a	DET
fnp-3528	949	39	miltefosine	miltefosine	ADJ
fnp-3528	949	40	transporter	transporter	NOUN
fnp-3528	949	41	in	in	ADP
fnp-3528	949	42	human	human	ADJ
fnp-3528	949	43	macrophages	macrophage	NOUN
fnp-3528	949	44	:	:	PUNCT
fnp-3528	949	45	impact	impact	NOUN
fnp-3528	949	46	on	on	ADP
fnp-3528	949	47	intracellular	intracellular	ADJ
fnp-3528	949	48	survival	survival	NOUN
fnp-3528	949	49	of	of	ADP
fnp-3528	949	50	leishmania	leishmania	NOUN
fnp-3528	949	51	(	(	PUNCT
fnp-3528	949	52	viannia	viannia	NOUN
fnp-3528	949	53	)	)	PUNCT
fnp-3528	949	54	panamensis	panamensis	NOUN
fnp-3528	949	55	.	.	PUNCT
fnp-3528	950	1	j	j	PROPN
fnp-3528	950	2	biol	biol	PROPN
fnp-3528	950	3	chem	chem	NOUN
fnp-3528	950	4	2016	2016	NUM
fnp-3528	950	5	,	,	PUNCT
fnp-3528	950	6	291	291	NUM
fnp-3528	950	7	,	,	PUNCT
fnp-3528	950	8	9638	9638	NUM
fnp-3528	950	9	-	-	SYM
fnp-3528	950	10	47	47	NUM
fnp-3528	950	11	.	.	PUNCT
fnp-3528	951	1	overbeck	overbeck	PROPN
fnp-3528	951	2	,	,	PUNCT
fnp-3528	951	3	t.	t.	PROPN
fnp-3528	951	4	r.	r.	PROPN
fnp-3528	951	5	;	;	PUNCT
fnp-3528	951	6	hupfeld	hupfeld	ADJ
fnp-3528	951	7	,	,	PUNCT
fnp-3528	951	8	t.	t.	PROPN
fnp-3528	951	9	;	;	PUNCT
fnp-3528	951	10	krause	krause	PROPN
fnp-3528	951	11	,	,	PUNCT
fnp-3528	951	12	d.	d.	PROPN
fnp-3528	951	13	;	;	PUNCT
fnp-3528	951	14	waldmann	waldmann	NOUN
fnp-3528	951	15	-	-	PUNCT
fnp-3528	951	16	beushausen	beushausen	PROPN
fnp-3528	951	17	,	,	PUNCT
fnp-3528	951	18	r.	r.	PROPN
fnp-3528	951	19	;	;	PUNCT
fnp-3528	951	20	chapuy	chapuy	NOUN
fnp-3528	951	21	,	,	PUNCT
fnp-3528	951	22	b.	b.	PROPN
fnp-3528	951	23	;	;	PUNCT
fnp-3528	951	24	guldenzoph	guldenzoph	PROPN
fnp-3528	951	25	,	,	PUNCT
fnp-3528	951	26	b.	b.	PROPN
fnp-3528	951	27	;	;	PUNCT
fnp-3528	951	28	aung	aung	PROPN
fnp-3528	951	29	,	,	PUNCT
fnp-3528	951	30	t.	t.	PROPN
fnp-3528	951	31	;	;	PUNCT
fnp-3528	951	32	inagaki	inagaki	PROPN
fnp-3528	951	33	,	,	PUNCT
fnp-3528	951	34	n.	n.	NOUN
fnp-3528	951	35	;	;	PUNCT
fnp-3528	951	36	schondube	schondube	NOUN
fnp-3528	951	37	,	,	PUNCT
fnp-3528	951	38	f.	f.	PROPN
fnp-3528	951	39	a.	a.	PROPN
fnp-3528	951	40	;	;	PUNCT
fnp-3528	951	41	danner	danner	NOUN
fnp-3528	951	42	,	,	PUNCT
fnp-3528	951	43	b.	b.	PROPN
fnp-3528	951	44	c.	c.	PROPN
fnp-3528	951	45	;	;	PUNCT
fnp-3528	951	46	truemper	truemper	PROPN
fnp-3528	951	47	,	,	PUNCT
fnp-3528	951	48	l.	l.	PROPN
fnp-3528	951	49	;	;	PUNCT
fnp-3528	951	50	wulf	wulf	PROPN
fnp-3528	951	51	,	,	PUNCT
fnp-3528	951	52	g.	g.	PROPN
fnp-3528	951	53	g.	g.	PROPN
fnp-3528	951	54	intracellular	intracellular	PROPN
fnp-3528	951	55	atp	atp	PROPN
fnp-3528	951	56	-	-	PUNCT
fnp-3528	951	57	binding	bind	VERB
fnp-3528	951	58	cassette	cassette	NOUN
fnp-3528	951	59	transporter	transporter	NOUN
fnp-3528	951	60	a3	a3	NOUN
fnp-3528	951	61	is	be	AUX
fnp-3528	951	62	expressed	express	VERB
fnp-3528	951	63	in	in	ADP
fnp-3528	951	64	lung	lung	NOUN
fnp-3528	951	65	cancer	cancer	NOUN
fnp-3528	951	66	cells	cell	NOUN
fnp-3528	951	67	and	and	CCONJ
fnp-3528	951	68	modulates	modulate	VERB
fnp-3528	951	69	susceptibility	susceptibility	NOUN
fnp-3528	951	70	to	to	ADP
fnp-3528	951	71	cisplatin	cisplatin	NOUN
fnp-3528	951	72	and	and	CCONJ
fnp-3528	951	73	paclitaxel	paclitaxel	PROPN
fnp-3528	951	74	.	.	PUNCT
fnp-3528	952	1	oncol	oncol	ADJ
fnp-3528	952	2	2013	2013	NUM
fnp-3528	952	3	,	,	PUNCT
fnp-3528	952	4	84	84	NUM
fnp-3528	952	5	,	,	PUNCT
fnp-3528	952	6	362	362	NUM
fnp-3528	952	7	-	-	SYM
fnp-3528	952	8	70	70	NUM
fnp-3528	952	9	.	.	PUNCT
fnp-3528	953	1	aberuyi	aberuyi	PROPN
fnp-3528	953	2	,	,	PUNCT
fnp-3528	953	3	n.	n.	NOUN
fnp-3528	953	4	;	;	PUNCT
fnp-3528	953	5	rahgozar	rahgozar	NOUN
fnp-3528	953	6	,	,	PUNCT
fnp-3528	953	7	s.	s.	PROPN
fnp-3528	953	8	;	;	PUNCT
fnp-3528	953	9	pourabutaleb	pourabutaleb	PROPN
fnp-3528	953	10	,	,	PUNCT
fnp-3528	953	11	e.	e.	PROPN
fnp-3528	953	12	;	;	PUNCT
fnp-3528	953	13	ghaedi	ghaedi	PROPN
fnp-3528	953	14	,	,	PUNCT
fnp-3528	953	15	k.	k.	PROPN
fnp-3528	953	16	selective	selective	PROPN
fnp-3528	953	17	dysregulation	dysregulation	NOUN
fnp-3528	953	18	of	of	ADP
fnp-3528	953	19	abc	abc	PROPN
fnp-3528	953	20	transporters	transporter	NOUN
fnp-3528	953	21	in	in	ADP
fnp-3528	953	22	methotrexate	methotrexate	NOUN
fnp-3528	953	23	-	-	PUNCT
fnp-3528	953	24	resistant	resistant	ADJ
fnp-3528	953	25	leukemia	leukemia	NOUN
fnp-3528	953	26	t	t	PROPN
fnp-3528	953	27	-	-	PUNCT
fnp-3528	953	28	cells	cell	NOUN
fnp-3528	953	29	can	can	AUX
fnp-3528	953	30	confer	confer	VERB
fnp-3528	953	31	cross	cross	NOUN
fnp-3528	953	32	-	-	NOUN
fnp-3528	953	33	resistance	resistance	NOUN
fnp-3528	953	34	to	to	ADP
fnp-3528	953	35	cytarabine	cytarabine	NOUN
fnp-3528	953	36	,	,	PUNCT
fnp-3528	953	37	vincristine	vincristine	NOUN
fnp-3528	953	38	and	and	CCONJ
fnp-3528	953	39	dexamethasone	dexamethasone	NOUN
fnp-3528	953	40	,	,	PUNCT
fnp-3528	953	41	but	but	CCONJ
fnp-3528	953	42	not	not	PART
fnp-3528	953	43	doxorubicin	doxorubicin	PROPN
fnp-3528	953	44	.	.	PUNCT
fnp-3528	954	1	curr	curr	PROPN
fnp-3528	954	2	res	res	PROPN
fnp-3528	954	3	transl	transl	PROPN
fnp-3528	954	4	med	me	VERB
fnp-3528	954	5	2021	2021	NUM
fnp-3528	954	6	,	,	PUNCT
fnp-3528	954	7	69	69	NUM
fnp-3528	954	8	,	,	PUNCT
fnp-3528	954	9	103269	103269	NUM
fnp-3528	954	10	.	.	PUNCT
fnp-3528	955	1	shroyer	shroyer	PROPN
fnp-3528	955	2	,	,	PUNCT
fnp-3528	955	3	n.	n.	PROPN
fnp-3528	955	4	f.	f.	PROPN
fnp-3528	955	5	;	;	PUNCT
fnp-3528	955	6	lewis	lewis	PROPN
fnp-3528	955	7	,	,	PUNCT
fnp-3528	955	8	r.	r.	PROPN
fnp-3528	955	9	a.	a.	PROPN
fnp-3528	955	10	;	;	PUNCT
fnp-3528	955	11	lupski	lupski	PROPN
fnp-3528	955	12	,	,	PUNCT
fnp-3528	955	13	j.	j.	PROPN
fnp-3528	955	14	r.	r.	PROPN
fnp-3528	955	15	analysis	analysis	NOUN
fnp-3528	955	16	of	of	ADP
fnp-3528	955	17	the	the	DET
fnp-3528	955	18	abcr	abcr	NOUN
fnp-3528	955	19	(	(	PUNCT
fnp-3528	955	20	abca4	abca4	ADJ
fnp-3528	955	21	)	)	PUNCT
fnp-3528	955	22	gene	gene	NOUN
fnp-3528	955	23	in	in	ADP
fnp-3528	955	24	4	4	NUM
fnp-3528	955	25	-	-	PUNCT
fnp-3528	955	26	aminoquinoline	aminoquinoline	ADJ
fnp-3528	955	27	retinopathy	retinopathy	NOUN
fnp-3528	955	28	:	:	PUNCT
fnp-3528	955	29	is	be	AUX
fnp-3528	955	30	retinal	retinal	ADJ
fnp-3528	955	31	toxicity	toxicity	NOUN
fnp-3528	955	32	by	by	ADP
fnp-3528	955	33	chloroquine	chloroquine	NOUN
fnp-3528	955	34	and	and	CCONJ
fnp-3528	955	35	hydroxychloroquine	hydroxychloroquine	PROPN
fnp-3528	955	36	related	relate	VERB
fnp-3528	955	37	to	to	ADP
fnp-3528	955	38	stargardt	stargardt	ADJ
fnp-3528	955	39	disease	disease	NOUN
fnp-3528	955	40	?	?	PUNCT
fnp-3528	956	1	am	be	AUX
fnp-3528	956	2	j	j	PROPN
fnp-3528	956	3	ophthalmol	ophthalmol	PROPN
fnp-3528	956	4	2001	2001	NUM
fnp-3528	956	5	,	,	PUNCT
fnp-3528	956	6	131	131	NUM
fnp-3528	956	7	,	,	PUNCT
fnp-3528	956	8	761	761	NUM
fnp-3528	956	9	-	-	SYM
fnp-3528	956	10	6	6	NUM
fnp-3528	956	11	.	.	PUNCT
fnp-3528	957	1	mack	mack	PROPN
fnp-3528	957	2	,	,	PUNCT
fnp-3528	957	3	h.	h.	PROPN
fnp-3528	957	4	g.	g.	PROPN
fnp-3528	957	5	;	;	PUNCT
fnp-3528	957	6	kowalski	kowalski	PROPN
fnp-3528	957	7	,	,	PUNCT
fnp-3528	957	8	t.	t.	PROPN
fnp-3528	957	9	;	;	PUNCT
fnp-3528	957	10	lucattini	lucattini	PROPN
fnp-3528	957	11	,	,	PUNCT
fnp-3528	957	12	a.	a.	NOUN
fnp-3528	957	13	;	;	PUNCT
fnp-3528	957	14	symons	symon	NOUN
fnp-3528	957	15	,	,	PUNCT
fnp-3528	957	16	r.	r.	PROPN
fnp-3528	957	17	a.	a.	PROPN
fnp-3528	957	18	;	;	PUNCT
fnp-3528	957	19	wicks	wick	NOUN
fnp-3528	957	20	,	,	PUNCT
fnp-3528	957	21	i.	i.	NOUN
fnp-3528	957	22	;	;	PUNCT
fnp-3528	957	23	hall	hall	PROPN
fnp-3528	957	24	,	,	PUNCT
fnp-3528	957	25	a.	a.	PROPN
fnp-3528	957	26	j.	j.	PROPN
fnp-3528	957	27	genetic	genetic	ADJ
fnp-3528	957	28	susceptibility	susceptibility	NOUN
fnp-3528	957	29	to	to	PART
fnp-3528	957	30	hydroxychloroquine	hydroxychloroquine	VERB
fnp-3528	957	31	retinal	retinal	ADJ
fnp-3528	957	32	toxicity	toxicity	NOUN
fnp-3528	957	33	.	.	PUNCT
fnp-3528	958	1	ophthalmic	ophthalmic	ADJ
fnp-3528	958	2	genet	genet	NOUN
fnp-3528	958	3	2020	2020	NUM
fnp-3528	958	4	,	,	PUNCT
fnp-3528	958	5	41	41	NUM
fnp-3528	958	6	,	,	PUNCT
fnp-3528	958	7	159	159	NUM
fnp-3528	958	8	-	-	SYM
fnp-3528	958	9	70	70	NUM
fnp-3528	958	10	.	.	PUNCT
fnp-3528	959	1	nagao	nagao	ADJ
fnp-3528	959	2	,	,	PUNCT
fnp-3528	959	3	k.	k.	PROPN
fnp-3528	959	4	;	;	PUNCT
fnp-3528	959	5	maeda	maeda	PROPN
fnp-3528	959	6	,	,	PUNCT
fnp-3528	959	7	m.	m.	NOUN
fnp-3528	959	8	;	;	PUNCT
fnp-3528	959	9	manucat	manucat	PROPN
fnp-3528	959	10	,	,	PUNCT
fnp-3528	959	11	n.	n.	PROPN
fnp-3528	959	12	b.	b.	PROPN
fnp-3528	959	13	;	;	PUNCT
fnp-3528	959	14	ueda	ueda	PROPN
fnp-3528	959	15	,	,	PUNCT
fnp-3528	959	16	k.	k.	PROPN
fnp-3528	959	17	cyclosporine	cyclosporine	VERB
fnp-3528	959	18	a	a	PRON
fnp-3528	959	19	and	and	CCONJ
fnp-3528	959	20	psc833	psc833	VERB
fnp-3528	959	21	inhibit	inhibit	NOUN
fnp-3528	959	22	abca1	abca1	NOUN
fnp-3528	959	23	function	function	NOUN
fnp-3528	959	24	via	via	ADP
fnp-3528	959	25	direct	direct	ADJ
fnp-3528	959	26	binding	binding	NOUN
fnp-3528	959	27	.	.	PUNCT
fnp-3528	960	1	biochim	biochim	PROPN
fnp-3528	960	2	biophys	biophy	NOUN
fnp-3528	960	3	acta	acta	PROPN
fnp-3528	960	4	2013	2013	NUM
fnp-3528	960	5	,	,	PUNCT
fnp-3528	960	6	1831	1831	NUM
fnp-3528	960	7	,	,	PUNCT
fnp-3528	960	8	398	398	NUM
fnp-3528	960	9	-	-	SYM
fnp-3528	960	10	406	406	NUM
fnp-3528	960	11	.	.	PUNCT
fnp-3528	961	1	wu	wu	PROPN
fnp-3528	961	2	,	,	PUNCT
fnp-3528	961	3	c.	c.	PROPN
fnp-3528	961	4	a.	a.	PROPN
fnp-3528	961	5	;	;	PUNCT
fnp-3528	961	6	tsujita	tsujita	PROPN
fnp-3528	961	7	,	,	PUNCT
fnp-3528	961	8	m.	m.	NOUN
fnp-3528	961	9	;	;	PUNCT
fnp-3528	961	10	hayashi	hayashi	PROPN
fnp-3528	961	11	,	,	PUNCT
fnp-3528	961	12	m.	m.	NOUN
fnp-3528	961	13	;	;	PUNCT
fnp-3528	961	14	yokoyama	yokoyama	PROPN
fnp-3528	961	15	,	,	PUNCT
fnp-3528	961	16	s.	s.	PROPN
fnp-3528	961	17	probucol	probucol	PROPN
fnp-3528	961	18	inactivates	inactivate	VERB
fnp-3528	961	19	abca1	abca1	NOUN
fnp-3528	961	20	in	in	ADP
fnp-3528	961	21	the	the	DET
fnp-3528	961	22	plasma	plasma	NOUN
fnp-3528	961	23	membrane	membrane	NOUN
fnp-3528	961	24	with	with	ADP
fnp-3528	961	25	respect	respect	NOUN
fnp-3528	961	26	to	to	ADP
fnp-3528	961	27	its	its	PRON
fnp-3528	961	28	mediation	mediation	NOUN
fnp-3528	961	29	of	of	ADP
fnp-3528	961	30	apolipoprotein	apolipoprotein	ADJ
fnp-3528	961	31	binding	bind	VERB
fnp-3528	961	32	and	and	CCONJ
fnp-3528	961	33	high	high	ADJ
fnp-3528	961	34	density	density	NOUN
fnp-3528	961	35	lipoprotein	lipoprotein	ADJ
fnp-3528	961	36	assembly	assembly	NOUN
fnp-3528	961	37	and	and	CCONJ
fnp-3528	961	38	to	to	ADP
fnp-3528	961	39	its	its	PRON
fnp-3528	961	40	proteolytic	proteolytic	ADJ
fnp-3528	961	41	degradation	degradation	NOUN
fnp-3528	961	42	.	.	PUNCT
fnp-3528	962	1	j	j	PROPN
fnp-3528	962	2	biol	biol	PROPN
fnp-3528	962	3	chem	chem	NOUN
fnp-3528	962	4	2004	2004	NUM
fnp-3528	962	5	,	,	PUNCT
fnp-3528	962	6	279	279	NUM
fnp-3528	962	7	,	,	PUNCT
fnp-3528	962	8	30168	30168	NUM
fnp-3528	962	9	-	-	SYM
fnp-3528	962	10	74	74	NUM
fnp-3528	962	11	.	.	PUNCT
fnp-3528	963	1	hamon	hamon	NOUN
fnp-3528	963	2	,	,	PUNCT
fnp-3528	963	3	y.	y.	PROPN
fnp-3528	963	4	;	;	PUNCT
fnp-3528	963	5	luciani	luciani	PROPN
fnp-3528	963	6	,	,	PUNCT
fnp-3528	963	7	m.	m.	PROPN
fnp-3528	963	8	f.	f.	PROPN
fnp-3528	963	9	;	;	PUNCT
fnp-3528	963	10	becq	becq	PROPN
fnp-3528	963	11	,	,	PUNCT
fnp-3528	963	12	f.	f.	PROPN
fnp-3528	963	13	;	;	PUNCT
fnp-3528	963	14	verrier	verrier	PROPN
fnp-3528	963	15	,	,	PUNCT
fnp-3528	963	16	b.	b.	PROPN
fnp-3528	963	17	;	;	PUNCT
fnp-3528	963	18	rubartelli	rubartelli	PROPN
fnp-3528	963	19	,	,	PUNCT
fnp-3528	963	20	a.	a.	NOUN
fnp-3528	963	21	;	;	PUNCT
fnp-3528	963	22	chimini	chimini	PROPN
fnp-3528	963	23	,	,	PUNCT
fnp-3528	963	24	g.	g.	PROPN
fnp-3528	963	25	interleukin-1beta	interleukin-1beta	PUNCT
fnp-3528	963	26	secretion	secretion	NOUN
fnp-3528	963	27	is	be	AUX
fnp-3528	963	28	impaired	impair	VERB
fnp-3528	963	29	by	by	ADP
fnp-3528	963	30	inhibitors	inhibitor	NOUN
fnp-3528	963	31	of	of	ADP
fnp-3528	963	32	the	the	DET
fnp-3528	963	33	atp	atp	NOUN
fnp-3528	963	34	binding	bind	VERB
fnp-3528	963	35	cassette	cassette	NOUN
fnp-3528	963	36	transporter	transporter	NOUN
fnp-3528	963	37	,	,	PUNCT
fnp-3528	963	38	abc1	abc1	PROPN
fnp-3528	963	39	.	.	PUNCT
fnp-3528	964	1	blood	blood	NOUN
fnp-3528	964	2	1997	1997	NUM
fnp-3528	964	3	,	,	PUNCT
fnp-3528	964	4	90	90	NUM
fnp-3528	964	5	,	,	PUNCT
fnp-3528	964	6	2911	2911	NUM
fnp-3528	964	7	-	-	SYM
fnp-3528	964	8	5	5	NUM
fnp-3528	964	9	.	.	PUNCT
fnp-3528	964	10	becq	becq	PROPN
fnp-3528	964	11	,	,	PUNCT
fnp-3528	964	12	f.	f.	PROPN
fnp-3528	964	13	;	;	PUNCT
fnp-3528	964	14	hamon	hamon	NOUN
fnp-3528	964	15	,	,	PUNCT
fnp-3528	964	16	y.	y.	PROPN
fnp-3528	964	17	;	;	PUNCT
fnp-3528	964	18	bajetto	bajetto	NOUN
fnp-3528	964	19	,	,	PUNCT
fnp-3528	964	20	a.	a.	PROPN
fnp-3528	964	21	;	;	PUNCT
fnp-3528	964	22	gola	gola	PROPN
fnp-3528	964	23	,	,	PUNCT
fnp-3528	964	24	m.	m.	NOUN
fnp-3528	964	25	;	;	PUNCT
fnp-3528	964	26	verrier	verrier	NOUN
fnp-3528	964	27	,	,	PUNCT
fnp-3528	964	28	b.	b.	PROPN
fnp-3528	964	29	;	;	PUNCT
fnp-3528	964	30	chimini	chimini	PROPN
fnp-3528	964	31	,	,	PUNCT
fnp-3528	964	32	g.	g.	PROPN
fnp-3528	964	33	abc1	abc1	PROPN
fnp-3528	964	34	,	,	PUNCT
fnp-3528	964	35	an	an	DET
fnp-3528	964	36	atp	atp	NOUN
fnp-3528	964	37	binding	bind	VERB
fnp-3528	964	38	cassette	cassette	NOUN
fnp-3528	964	39	transporter	transporter	NOUN
fnp-3528	964	40	required	require	VERB
fnp-3528	964	41	for	for	ADP
fnp-3528	964	42	phagocytosis	phagocytosis	NOUN
fnp-3528	964	43	of	of	ADP
fnp-3528	964	44	apoptotic	apoptotic	ADJ
fnp-3528	964	45	cells	cell	NOUN
fnp-3528	964	46	,	,	PUNCT
fnp-3528	964	47	generates	generate	VERB
fnp-3528	964	48	a	a	DET
fnp-3528	964	49	regulated	regulated	ADJ
fnp-3528	964	50	anion	anion	NOUN
fnp-3528	964	51	flux	flux	NOUN
fnp-3528	964	52	after	after	ADP
fnp-3528	964	53	expression	expression	NOUN
fnp-3528	964	54	in	in	ADP
fnp-3528	964	55	xenopus	xenopus	PROPN
fnp-3528	964	56	laevis	laevis	ADJ
fnp-3528	964	57	oocytes	oocyte	NOUN
fnp-3528	964	58	.	.	PUNCT
fnp-3528	965	1	j	j	PROPN
fnp-3528	965	2	biol	biol	PROPN
fnp-3528	965	3	chem	chem	NOUN
fnp-3528	965	4	1997	1997	NUM
fnp-3528	965	5	,	,	PUNCT
fnp-3528	965	6	272	272	NUM
fnp-3528	965	7	,	,	PUNCT
fnp-3528	965	8	2695	2695	NUM
fnp-3528	965	9	-	-	SYM
fnp-3528	965	10	9	9	NUM
fnp-3528	965	11	.	.	PUNCT
fnp-3528	965	12	le	le	PROPN
fnp-3528	965	13	goff	goff	PROPN
fnp-3528	965	14	,	,	PUNCT
fnp-3528	965	15	w.	w.	PROPN
fnp-3528	965	16	;	;	PUNCT
fnp-3528	965	17	peng	peng	PROPN
fnp-3528	965	18	,	,	PUNCT
fnp-3528	965	19	d.	d.	PROPN
fnp-3528	965	20	q.	q.	PROPN
fnp-3528	965	21	;	;	PUNCT
fnp-3528	965	22	settle	settle	NOUN
fnp-3528	965	23	,	,	PUNCT
fnp-3528	965	24	m.	m.	NOUN
fnp-3528	965	25	;	;	PUNCT
fnp-3528	965	26	brubaker	brubaker	PROPN
fnp-3528	965	27	,	,	PUNCT
fnp-3528	965	28	g.	g.	PROPN
fnp-3528	965	29	;	;	PUNCT
fnp-3528	965	30	morton	morton	PROPN
fnp-3528	965	31	,	,	PUNCT
fnp-3528	965	32	r.	r.	PROPN
fnp-3528	965	33	e.	e.	PROPN
fnp-3528	965	34	;	;	PUNCT
fnp-3528	965	35	smith	smith	PROPN
fnp-3528	965	36	,	,	PUNCT
fnp-3528	965	37	j.	j.	PROPN
fnp-3528	965	38	d.	d.	PROPN
fnp-3528	965	39	cyclosporin	cyclosporin	VERB
fnp-3528	965	40	a	a	DET
fnp-3528	965	41	traps	trap	NOUN
fnp-3528	965	42	abca1	abca1	NOUN
fnp-3528	965	43	at	at	ADP
fnp-3528	965	44	the	the	DET
fnp-3528	965	45	plasma	plasma	NOUN
fnp-3528	965	46	membrane	membrane	NOUN
fnp-3528	965	47	and	and	CCONJ
fnp-3528	965	48	inhibits	inhibit	VERB
fnp-3528	965	49	abca1	abca1	NOUN
fnp-3528	965	50	-	-	PUNCT
fnp-3528	965	51	mediated	mediate	VERB
fnp-3528	965	52	lipid	lipid	NOUN
fnp-3528	965	53	efflux	efflux	VERB
fnp-3528	965	54	to	to	PART
fnp-3528	965	55	apolipoprotein	apolipoprotein	VERB
fnp-3528	965	56	a	a	DET
fnp-3528	965	57	-	-	PUNCT
fnp-3528	965	58	i.	i.	NOUN
fnp-3528	965	59	arterioscler	arterioscler	PROPN
fnp-3528	965	60	thromb	thromb	PROPN
fnp-3528	965	61	vasc	vasc	PROPN
fnp-3528	965	62	biol	biol	PROPN
fnp-3528	965	63	2004	2004	NUM
fnp-3528	965	64	,	,	PUNCT
fnp-3528	965	65	24	24	NUM
fnp-3528	965	66	,	,	PUNCT
fnp-3528	965	67	2155	2155	NUM
fnp-3528	965	68	-	-	SYM
fnp-3528	965	69	61	61	NUM
fnp-3528	965	70	.	.	PUNCT
fnp-3528	966	1	monzel	monzel	PROPN
fnp-3528	966	2	,	,	PUNCT
fnp-3528	966	3	j.	j.	PROPN
fnp-3528	966	4	v.	v.	PROPN
fnp-3528	966	5	;	;	PUNCT
fnp-3528	966	6	budde	budde	PROPN
fnp-3528	966	7	,	,	PUNCT
fnp-3528	966	8	t.	t.	PROPN
fnp-3528	966	9	;	;	PUNCT
fnp-3528	966	10	meyer	meyer	PROPN
fnp-3528	966	11	zu	zu	PROPN
fnp-3528	966	12	schwabedissen	schwabedissen	PROPN
fnp-3528	966	13	,	,	PUNCT
fnp-3528	966	14	h.	h.	PROPN
fnp-3528	966	15	e.	e.	PROPN
fnp-3528	966	16	;	;	PUNCT
fnp-3528	966	17	schwebe	schwebe	NOUN
fnp-3528	966	18	,	,	PUNCT
fnp-3528	966	19	m.	m.	NOUN
fnp-3528	966	20	;	;	PUNCT
fnp-3528	966	21	bien	bien	PROPN
fnp-3528	966	22	-	-	PUNCT
fnp-3528	966	23	moller	moller	PROPN
fnp-3528	966	24	,	,	PUNCT
fnp-3528	966	25	s.	s.	PROPN
fnp-3528	966	26	;	;	PUNCT
fnp-3528	966	27	lutjohann	lutjohann	PROPN
fnp-3528	966	28	,	,	PUNCT
fnp-3528	966	29	d.	d.	PROPN
fnp-3528	966	30	;	;	PUNCT
fnp-3528	966	31	kroemer	kroemer	PROPN
fnp-3528	966	32	,	,	PUNCT
fnp-3528	966	33	h.	h.	PROPN
fnp-3528	966	34	k.	k.	PROPN
fnp-3528	966	35	;	;	PUNCT
fnp-3528	966	36	jedlitschky	jedlitschky	PROPN
fnp-3528	966	37	,	,	PUNCT
fnp-3528	966	38	g.	g.	PROPN
fnp-3528	966	39	;	;	PUNCT
fnp-3528	966	40	grube	grube	PROPN
fnp-3528	966	41	,	,	PUNCT
fnp-3528	967	1	m.	m.	NOUN
fnp-3528	967	2	doxorubicin	doxorubicin	PROPN
fnp-3528	967	3	enhances	enhance	VERB
fnp-3528	967	4	oxysterol	oxysterol	NOUN
fnp-3528	967	5	levels	level	NOUN
fnp-3528	967	6	resulting	result	VERB
fnp-3528	967	7	in	in	ADP
fnp-3528	967	8	a	a	DET
fnp-3528	967	9	lxr	lxr	NOUN
fnp-3528	967	10	-	-	PUNCT
fnp-3528	967	11	mediated	mediate	VERB
fnp-3528	967	12	upregulation	upregulation	NOUN
fnp-3528	967	13	of	of	ADP
fnp-3528	967	14	cardiac	cardiac	ADJ
fnp-3528	967	15	cholesterol	cholesterol	NOUN
fnp-3528	967	16	transporters	transporter	NOUN
fnp-3528	967	17	.	.	PUNCT
fnp-3528	968	1	biochem	biochem	PROPN
fnp-3528	968	2	pharmacol	pharmacol	PROPN
fnp-3528	968	3	2017	2017	NUM
fnp-3528	968	4	,	,	PUNCT
fnp-3528	968	5	144	144	NUM
fnp-3528	968	6	,	,	PUNCT
fnp-3528	968	7	108	108	NUM
fnp-3528	968	8	-	-	SYM
fnp-3528	968	9	119	119	NUM
fnp-3528	968	10	.	.	PUNCT
fnp-3528	969	1	burns	burn	NOUN
fnp-3528	969	2	,	,	PUNCT
fnp-3528	969	3	v.	v.	PROPN
fnp-3528	969	4	e.	e.	PROPN
fnp-3528	969	5	;	;	PUNCT
fnp-3528	969	6	kerppola	kerppola	PROPN
fnp-3528	969	7	,	,	PUNCT
fnp-3528	969	8	t.	t.	PROPN
fnp-3528	969	9	k.	k.	PROPN
fnp-3528	969	10	atr-101	atr-101	PROPN
fnp-3528	969	11	inhibits	inhibit	VERB
fnp-3528	969	12	cholesterol	cholesterol	NOUN
fnp-3528	969	13	efflux	efflux	NOUN
fnp-3528	969	14	and	and	CCONJ
fnp-3528	969	15	cortisol	cortisol	ADJ
fnp-3528	969	16	secretion	secretion	NOUN
fnp-3528	969	17	by	by	ADP
fnp-3528	969	18	atp	atp	NOUN
fnp-3528	969	19	-	-	PUNCT
fnp-3528	969	20	binding	bind	VERB
fnp-3528	969	21	cassette	cassette	NOUN
fnp-3528	969	22	transporters	transporter	NOUN
fnp-3528	969	23	,	,	PUNCT
fnp-3528	969	24	causing	cause	VERB
fnp-3528	969	25	cytotoxic	cytotoxic	ADJ
fnp-3528	969	26	cholesterol	cholesterol	NOUN
fnp-3528	969	27	accumulation	accumulation	NOUN
fnp-3528	969	28	in	in	ADP
fnp-3528	969	29	adrenocortical	adrenocortical	ADJ
fnp-3528	969	30	carcinoma	carcinoma	NOUN
fnp-3528	969	31	cells	cell	NOUN
fnp-3528	969	32	.	.	PUNCT
fnp-3528	970	1	br	br	PROPN
fnp-3528	971	1	j	j	PROPN
fnp-3528	971	2	pharmacol	pharmacol	PROPN
fnp-3528	971	3	2017	2017	NUM
fnp-3528	971	4	,	,	PUNCT
fnp-3528	971	5	174	174	NUM
fnp-3528	971	6	,	,	PUNCT
fnp-3528	971	7	3315	3315	NUM
fnp-3528	971	8	-	-	SYM
fnp-3528	971	9	32	32	NUM
fnp-3528	971	10	.	.	PUNCT
fnp-3528	972	1	zhao	zhao	PROPN
fnp-3528	972	2	,	,	PUNCT
fnp-3528	972	3	j.	j.	PROPN
fnp-3528	972	4	f.	f.	PROPN
fnp-3528	972	5	;	;	PUNCT
fnp-3528	972	6	jim	jim	PROPN
fnp-3528	972	7	leu	leu	PROPN
fnp-3528	972	8	,	,	PUNCT
fnp-3528	972	9	s.	s.	PROPN
fnp-3528	972	10	j.	j.	PROPN
fnp-3528	972	11	;	;	PUNCT
fnp-3528	972	12	shyue	shyue	PROPN
fnp-3528	972	13	,	,	PUNCT
fnp-3528	972	14	s.	s.	PROPN
fnp-3528	972	15	k.	k.	PROPN
fnp-3528	972	16	;	;	PUNCT
fnp-3528	972	17	su	su	PROPN
fnp-3528	972	18	,	,	PUNCT
fnp-3528	972	19	k.	k.	PROPN
fnp-3528	972	20	h.	h.	PROPN
fnp-3528	972	21	;	;	PUNCT
fnp-3528	972	22	wei	wei	PROPN
fnp-3528	972	23	,	,	PUNCT
fnp-3528	972	24	j.	j.	PROPN
fnp-3528	972	25	;	;	PUNCT
fnp-3528	972	26	lee	lee	PROPN
fnp-3528	972	27	,	,	PUNCT
fnp-3528	972	28	t.	t.	PROPN
fnp-3528	972	29	s.	s.	PROPN
fnp-3528	972	30	novel	novel	PROPN
fnp-3528	972	31	effect	effect	NOUN
fnp-3528	972	32	of	of	ADP
fnp-3528	972	33	paeonol	paeonol	NOUN
fnp-3528	972	34	on	on	ADP
fnp-3528	972	35	the	the	DET
fnp-3528	972	36	formation	formation	NOUN
fnp-3528	972	37	of	of	ADP
fnp-3528	972	38	foam	foam	NOUN
fnp-3528	972	39	cells	cell	NOUN
fnp-3528	972	40	:	:	PUNCT
fnp-3528	972	41	promotion	promotion	NOUN
fnp-3528	972	42	of	of	ADP
fnp-3528	972	43	lxralpha	lxralpha	NOUN
fnp-3528	972	44	-	-	PUNCT
fnp-3528	972	45	abca1	abca1	NOUN
fnp-3528	972	46	-	-	PUNCT
fnp-3528	972	47	dependent	dependent	ADJ
fnp-3528	972	48	cholesterol	cholesterol	NOUN
fnp-3528	972	49	efflux	efflux	VERB
fnp-3528	972	50	in	in	ADP
fnp-3528	972	51	macrophages	macrophage	NOUN
fnp-3528	972	52	.	.	PUNCT
fnp-3528	973	1	am	be	AUX
fnp-3528	973	2	j	j	PROPN
fnp-3528	973	3	chin	chin	PROPN
fnp-3528	973	4	med	med	PROPN
fnp-3528	973	5	2013	2013	NUM
fnp-3528	973	6	,	,	PUNCT
fnp-3528	973	7	41	41	NUM
fnp-3528	973	8	,	,	PUNCT
fnp-3528	973	9	1079	1079	NUM
fnp-3528	973	10	-	-	SYM
fnp-3528	973	11	96	96	NUM
fnp-3528	973	12	.	.	PUNCT
fnp-3528	973	13	campia	campia	PROPN
fnp-3528	973	14	,	,	PUNCT
fnp-3528	973	15	i.	i.	PROPN
fnp-3528	973	16	;	;	PUNCT
fnp-3528	973	17	sala	sala	PROPN
fnp-3528	973	18	,	,	PUNCT
fnp-3528	973	19	v.	v.	PROPN
fnp-3528	973	20	;	;	PUNCT
fnp-3528	973	21	kopecka	kopecka	PROPN
fnp-3528	973	22	,	,	PUNCT
fnp-3528	973	23	j.	j.	PROPN
fnp-3528	973	24	;	;	PUNCT
fnp-3528	973	25	leo	leo	PROPN
fnp-3528	973	26	,	,	PUNCT
fnp-3528	973	27	c.	c.	PROPN
fnp-3528	973	28	;	;	PUNCT
fnp-3528	973	29	mitro	mitro	NOUN
fnp-3528	973	30	,	,	PUNCT
fnp-3528	973	31	n.	n.	NOUN
fnp-3528	973	32	;	;	PUNCT
fnp-3528	973	33	costamagna	costamagna	PROPN
fnp-3528	973	34	,	,	PUNCT
fnp-3528	973	35	c.	c.	PROPN
fnp-3528	973	36	;	;	PUNCT
fnp-3528	973	37	caruso	caruso	PROPN
fnp-3528	973	38	,	,	PUNCT
fnp-3528	973	39	d.	d.	PROPN
fnp-3528	973	40	;	;	PUNCT
fnp-3528	973	41	pescarmona	pescarmona	PROPN
fnp-3528	973	42	,	,	PUNCT
fnp-3528	973	43	g.	g.	PROPN
fnp-3528	973	44	;	;	PUNCT
fnp-3528	973	45	crepaldi	crepaldi	PROPN
fnp-3528	973	46	,	,	PUNCT
fnp-3528	973	47	t.	t.	PROPN
fnp-3528	973	48	;	;	PUNCT
fnp-3528	973	49	ghigo	ghigo	PROPN
fnp-3528	973	50	,	,	PUNCT
fnp-3528	973	51	d.	d.	PROPN
fnp-3528	973	52	;	;	PUNCT
fnp-3528	973	53	bosia	bosia	PROPN
fnp-3528	973	54	,	,	PUNCT
fnp-3528	973	55	a.	a.	NOUN
fnp-3528	973	56	;	;	PUNCT
fnp-3528	973	57	riganti	riganti	PROPN
fnp-3528	973	58	,	,	PUNCT
fnp-3528	973	59	c.	c.	PROPN
fnp-3528	973	60	digoxin	digoxin	PROPN
fnp-3528	973	61	and	and	CCONJ
fnp-3528	973	62	ouabain	ouabain	AUX
fnp-3528	973	63	induce	induce	VERB
fnp-3528	973	64	the	the	DET
fnp-3528	973	65	efflux	efflux	NOUN
fnp-3528	973	66	of	of	ADP
fnp-3528	973	67	cholesterol	cholesterol	NOUN
fnp-3528	973	68	via	via	ADP
fnp-3528	973	69	liver	liver	NOUN
fnp-3528	973	70	x	x	SYM
fnp-3528	973	71	receptor	receptor	NOUN
fnp-3528	973	72	signalling	signal	VERB
fnp-3528	973	73	and	and	CCONJ
fnp-3528	973	74	the	the	DET
fnp-3528	973	75	synthesis	synthesis	NOUN
fnp-3528	973	76	of	of	ADP
fnp-3528	973	77	atp	atp	PROPN
fnp-3528	973	78	in	in	ADP
fnp-3528	973	79	cardiomyocytes	cardiomyocyte	NOUN
fnp-3528	973	80	.	.	PUNCT
fnp-3528	974	1	biochem	biochem	PROPN
fnp-3528	974	2	j	j	PROPN
fnp-3528	974	3	2012	2012	NUM
fnp-3528	974	4	,	,	PUNCT
fnp-3528	974	5	447	447	NUM
fnp-3528	974	6	,	,	PUNCT
fnp-3528	974	7	301	301	NUM
fnp-3528	974	8	-	-	SYM
fnp-3528	974	9	11	11	NUM
fnp-3528	974	10	.	.	PUNCT
fnp-3528	975	1	chen	chen	PROPN
fnp-3528	975	2	,	,	PUNCT
fnp-3528	975	3	c.	c.	PROPN
fnp-3528	975	4	y.	y.	PROPN
fnp-3528	975	5	;	;	PUNCT
fnp-3528	975	6	shyue	shyue	PROPN
fnp-3528	975	7	,	,	PUNCT
fnp-3528	975	8	s.	s.	PROPN
fnp-3528	975	9	k.	k.	PROPN
fnp-3528	975	10	;	;	PUNCT
fnp-3528	975	11	ching	ching	PROPN
fnp-3528	975	12	,	,	PUNCT
fnp-3528	975	13	l.	l.	PROPN
fnp-3528	975	14	c.	c.	PROPN
fnp-3528	975	15	;	;	PUNCT
fnp-3528	975	16	su	su	PROPN
fnp-3528	975	17	,	,	PUNCT
fnp-3528	975	18	k.	k.	PROPN
fnp-3528	975	19	h.	h.	PROPN
fnp-3528	975	20	;	;	PUNCT
fnp-3528	975	21	wu	wu	PROPN
fnp-3528	975	22	,	,	PUNCT
fnp-3528	975	23	y.	y.	PROPN
fnp-3528	975	24	l.	l.	PROPN
fnp-3528	975	25	;	;	PUNCT
fnp-3528	975	26	kou	kou	PROPN
fnp-3528	975	27	,	,	PUNCT
fnp-3528	975	28	y.	y.	PROPN
fnp-3528	975	29	r.	r.	PROPN
fnp-3528	975	30	;	;	PUNCT
fnp-3528	975	31	chiang	chiang	PROPN
fnp-3528	975	32	,	,	PUNCT
fnp-3528	975	33	a.	a.	NOUN
fnp-3528	975	34	n.	n.	PROPN
fnp-3528	975	35	;	;	PUNCT
fnp-3528	975	36	pan	pan	PROPN
fnp-3528	975	37	,	,	PUNCT
fnp-3528	975	38	c.	c.	PROPN
fnp-3528	975	39	c.	c.	PROPN
fnp-3528	975	40	;	;	PUNCT
fnp-3528	975	41	lee	lee	PROPN
fnp-3528	975	42	,	,	PUNCT
fnp-3528	975	43	t.	t.	PROPN
fnp-3528	975	44	s.	s.	PROPN
fnp-3528	975	45	wogonin	wogonin	PROPN
fnp-3528	975	46	promotes	promote	VERB
fnp-3528	975	47	cholesterol	cholesterol	NOUN
fnp-3528	975	48	efflux	efflux	NOUN
fnp-3528	975	49	by	by	ADP
fnp-3528	975	50	increasing	increase	VERB
fnp-3528	975	51	protein	protein	NOUN
fnp-3528	975	52	phosphatase	phosphatase	NOUN
fnp-3528	975	53	2b	2b	NOUN
fnp-3528	975	54	-	-	ADJ
fnp-3528	975	55	dependent	dependent	ADJ
fnp-3528	975	56	dephosphorylation	dephosphorylation	NOUN
fnp-3528	975	57	at	at	ADP
fnp-3528	975	58	atp	atp	NOUN
fnp-3528	975	59	-	-	PUNCT
fnp-3528	975	60	binding	bind	VERB
fnp-3528	975	61	cassette	cassette	NOUN
fnp-3528	975	62	transporter	transporter	NOUN
fnp-3528	975	63	-	-	PUNCT
fnp-3528	975	64	a1	a1	NOUN
fnp-3528	975	65	in	in	ADP
fnp-3528	975	66	macrophages	macrophage	NOUN
fnp-3528	975	67	.	.	PUNCT
fnp-3528	976	1	j	j	PROPN
fnp-3528	976	2	nutr	nutr	PROPN
fnp-3528	976	3	biochem	biochem	PROPN
fnp-3528	976	4	2011	2011	NUM
fnp-3528	976	5	,	,	PUNCT
fnp-3528	976	6	22	22	NUM
fnp-3528	976	7	,	,	PUNCT
fnp-3528	976	8	1015	1015	NUM
fnp-3528	976	9	-	-	SYM
fnp-3528	976	10	21	21	NUM
fnp-3528	976	11	.	.	PUNCT
fnp-3528	977	1	howard	howard	PROPN
fnp-3528	977	2	,	,	PUNCT
fnp-3528	977	3	a.	a.	PROPN
fnp-3528	977	4	d.	d.	PROPN
fnp-3528	977	5	;	;	PUNCT
fnp-3528	977	6	verghese	verghese	PROPN
fnp-3528	977	7	,	,	PUNCT
fnp-3528	977	8	p.	p.	PROPN
fnp-3528	977	9	b.	b.	PROPN
fnp-3528	978	1	;	;	PUNCT
fnp-3528	978	2	arrese	arrese	PROPN
fnp-3528	978	3	,	,	PUNCT
fnp-3528	978	4	e.	e.	PROPN
fnp-3528	978	5	l.	l.	PROPN
fnp-3528	978	6	;	;	PUNCT
fnp-3528	978	7	soulages	soulage	NOUN
fnp-3528	978	8	,	,	PUNCT
fnp-3528	978	9	j.	j.	PROPN
fnp-3528	978	10	l.	l.	PROPN
fnp-3528	978	11	characterization	characterization	PROPN
fnp-3528	978	12	of	of	ADP
fnp-3528	978	13	apoa	apoa	PROPN
fnp-3528	978	14	-	-	PUNCT
fnp-3528	978	15	i	i	NOUN
fnp-3528	978	16	-	-	PUNCT
fnp-3528	978	17	dependent	dependent	ADJ
fnp-3528	978	18	lipid	lipid	NOUN
fnp-3528	978	19	efflux	efflux	VERB
fnp-3528	978	20	from	from	ADP
fnp-3528	978	21	adipocytes	adipocyte	NOUN
fnp-3528	978	22	and	and	CCONJ
fnp-3528	978	23	role	role	NOUN
fnp-3528	978	24	of	of	ADP
fnp-3528	978	25	abca1	abca1	NOUN
fnp-3528	978	26	.	.	PUNCT
fnp-3528	979	1	mol	mol	ADP
fnp-3528	979	2	cell	cell	NOUN
fnp-3528	979	3	biochem	biochem	NOUN
fnp-3528	979	4	2010	2010	NUM
fnp-3528	979	5	,	,	PUNCT
fnp-3528	979	6	343	343	NUM
fnp-3528	979	7	,	,	PUNCT
fnp-3528	979	8	115	115	NUM
fnp-3528	979	9	-	-	SYM
fnp-3528	979	10	24	24	NUM
fnp-3528	979	11	.	.	PUNCT
fnp-3528	979	12	lee	lee	PROPN
fnp-3528	979	13	,	,	PUNCT
fnp-3528	979	14	t.	t.	PROPN
fnp-3528	979	15	s.	s.	PROPN
fnp-3528	979	16	;	;	PUNCT
fnp-3528	979	17	pan	pan	PROPN
fnp-3528	979	18	,	,	PUNCT
fnp-3528	979	19	c.	c.	PROPN
fnp-3528	979	20	c.	c.	PROPN
fnp-3528	979	21	;	;	PUNCT
fnp-3528	979	22	peng	peng	PROPN
fnp-3528	979	23	,	,	PUNCT
fnp-3528	979	24	c.	c.	PROPN
fnp-3528	979	25	c.	c.	PROPN
fnp-3528	979	26	;	;	PUNCT
fnp-3528	979	27	kou	kou	PROPN
fnp-3528	979	28	,	,	PUNCT
fnp-3528	979	29	y.	y.	PROPN
fnp-3528	979	30	r.	r.	PROPN
fnp-3528	979	31	;	;	PUNCT
fnp-3528	979	32	chen	chen	PROPN
fnp-3528	979	33	,	,	PUNCT
fnp-3528	979	34	c.	c.	PROPN
fnp-3528	979	35	y.	y.	PROPN
fnp-3528	979	36	;	;	PUNCT
fnp-3528	979	37	ching	ching	PROPN
fnp-3528	979	38	,	,	PUNCT
fnp-3528	979	39	l.	l.	PROPN
fnp-3528	979	40	c.	c.	PROPN
fnp-3528	979	41	;	;	PUNCT
fnp-3528	979	42	tsai	tsai	PROPN
fnp-3528	979	43	,	,	PUNCT
fnp-3528	979	44	t.	t.	PROPN
fnp-3528	979	45	h.	h.	PROPN
fnp-3528	979	46	;	;	PUNCT
fnp-3528	979	47	chen	chen	PROPN
fnp-3528	979	48	,	,	PUNCT
fnp-3528	979	49	s.	s.	PROPN
fnp-3528	979	50	f.	f.	PROPN
fnp-3528	979	51	;	;	PUNCT
fnp-3528	979	52	lyu	lyu	NOUN
fnp-3528	979	53	,	,	PUNCT
fnp-3528	979	54	p.	p.	PROPN
fnp-3528	979	55	c.	c.	PROPN
fnp-3528	979	56	;	;	PUNCT
fnp-3528	979	57	shyue	shyue	PROPN
fnp-3528	979	58	,	,	PUNCT
fnp-3528	979	59	s.	s.	PROPN
fnp-3528	979	60	k.	k.	PROPN
fnp-3528	979	61	anti	anti	ADJ
fnp-3528	979	62	-	-	ADJ
fnp-3528	979	63	atherogenic	atherogenic	ADJ
fnp-3528	979	64	effect	effect	NOUN
fnp-3528	979	65	of	of	ADP
fnp-3528	979	66	berberine	berberine	NOUN
fnp-3528	979	67	on	on	ADP
fnp-3528	979	68	lxralpha	lxralpha	NOUN
fnp-3528	979	69	-	-	PUNCT
fnp-3528	979	70	abca1	abca1	NOUN
fnp-3528	979	71	-	-	PUNCT
fnp-3528	979	72	dependent	dependent	ADJ
fnp-3528	979	73	cholesterol	cholesterol	NOUN
fnp-3528	979	74	efflux	efflux	VERB
fnp-3528	979	75	in	in	ADP
fnp-3528	979	76	macrophages	macrophage	NOUN
fnp-3528	979	77	.	.	PUNCT
fnp-3528	980	1	j	j	PROPN
fnp-3528	980	2	cell	cell	NOUN
fnp-3528	980	3	biochem	biochem	NOUN
fnp-3528	980	4	2010	2010	NUM
fnp-3528	980	5	,	,	PUNCT
fnp-3528	980	6	111	111	NUM
fnp-3528	980	7	,	,	PUNCT
fnp-3528	980	8	104	104	NUM
fnp-3528	980	9	-	-	SYM
fnp-3528	980	10	10	10	NUM
fnp-3528	980	11	.	.	PUNCT
fnp-3528	981	1	duncan	duncan	PROPN
fnp-3528	981	2	,	,	PUNCT
fnp-3528	981	3	k.	k.	PROPN
fnp-3528	981	4	g.	g.	PROPN
fnp-3528	981	5	;	;	PUNCT
fnp-3528	981	6	hosseini	hosseini	PROPN
fnp-3528	981	7	,	,	PUNCT
fnp-3528	981	8	k.	k.	PROPN
fnp-3528	981	9	;	;	PUNCT
fnp-3528	981	10	bailey	bailey	PROPN
fnp-3528	981	11	,	,	PUNCT
fnp-3528	981	12	k.	k.	PROPN
fnp-3528	981	13	r.	r.	PROPN
fnp-3528	981	14	;	;	PUNCT
fnp-3528	981	15	yang	yang	PROPN
fnp-3528	981	16	,	,	PUNCT
fnp-3528	981	17	h.	h.	PROPN
fnp-3528	981	18	;	;	PUNCT
fnp-3528	981	19	lowe	lowe	PROPN
fnp-3528	981	20	,	,	PUNCT
fnp-3528	981	21	r.	r.	PROPN
fnp-3528	981	22	j.	j.	PROPN
fnp-3528	981	23	;	;	PUNCT
fnp-3528	981	24	matthes	matthe	NOUN
fnp-3528	981	25	,	,	PUNCT
fnp-3528	981	26	m.	m.	NOUN
fnp-3528	981	27	t.	t.	PROPN
fnp-3528	981	28	;	;	PUNCT
fnp-3528	981	29	kane	kane	PROPN
fnp-3528	981	30	,	,	PUNCT
fnp-3528	981	31	j.	j.	PROPN
fnp-3528	981	32	p.	p.	PROPN
fnp-3528	981	33	;	;	PUNCT
fnp-3528	981	34	lavail	lavail	NOUN
fnp-3528	981	35	,	,	PUNCT
fnp-3528	981	36	m.	m.	NOUN
fnp-3528	981	37	m.	m.	NOUN
fnp-3528	981	38	;	;	PUNCT
fnp-3528	981	39	schwartz	schwartz	PROPN
fnp-3528	981	40	,	,	PUNCT
fnp-3528	981	41	d.	d.	PROPN
fnp-3528	981	42	m.	m.	PROPN
fnp-3528	981	43	;	;	PUNCT
fnp-3528	981	44	duncan	duncan	PROPN
fnp-3528	981	45	,	,	PUNCT
fnp-3528	981	46	j.	j.	PROPN
fnp-3528	981	47	l.	l.	PROPN
fnp-3528	981	48	expression	expression	NOUN
fnp-3528	981	49	of	of	ADP
fnp-3528	981	50	reverse	reverse	ADJ
fnp-3528	981	51	cholesterol	cholesterol	NOUN
fnp-3528	981	52	transport	transport	NOUN
fnp-3528	981	53	proteins	protein	NOUN
fnp-3528	981	54	atp	atp	NOUN
fnp-3528	981	55	-	-	PUNCT
fnp-3528	981	56	binding	bind	VERB
fnp-3528	981	57	cassette	cassette	NOUN
fnp-3528	981	58	a1	a1	NOUN
fnp-3528	981	59	(	(	PUNCT
fnp-3528	981	60	abca1	abca1	NOUN
fnp-3528	981	61	)	)	PUNCT
fnp-3528	981	62	and	and	CCONJ
fnp-3528	981	63	scavenger	scavenger	NOUN
fnp-3528	981	64	receptor	receptor	NOUN
fnp-3528	981	65	bi	bi	NOUN
fnp-3528	981	66	(	(	PUNCT
fnp-3528	981	67	sr	sr	PROPN
fnp-3528	981	68	-	-	PUNCT
fnp-3528	981	69	bi	bi	NOUN
fnp-3528	981	70	)	)	PUNCT
fnp-3528	981	71	in	in	ADP
fnp-3528	981	72	the	the	DET
fnp-3528	981	73	retina	retina	NOUN
fnp-3528	981	74	and	and	CCONJ
fnp-3528	981	75	retinal	retinal	ADJ
fnp-3528	981	76	pigment	pigment	NOUN
fnp-3528	981	77	epithelium	epithelium	NOUN
fnp-3528	981	78	.	.	PUNCT
fnp-3528	982	1	br	br	PROPN
fnp-3528	983	1	j	j	PROPN
fnp-3528	983	2	ophthalmol	ophthalmol	PROPN
fnp-3528	983	3	2009	2009	NUM
fnp-3528	983	4	,	,	PUNCT
fnp-3528	983	5	93	93	NUM
fnp-3528	983	6	,	,	PUNCT
fnp-3528	983	7	1116	1116	NUM
fnp-3528	983	8	-	-	SYM
fnp-3528	983	9	20	20	NUM
fnp-3528	983	10	.	.	PUNCT
fnp-3528	984	1	wang	wang	PROPN
fnp-3528	984	2	,	,	PUNCT
fnp-3528	984	3	j.	j.	PROPN
fnp-3528	984	4	;	;	PUNCT
fnp-3528	984	5	zhang	zhang	PROPN
fnp-3528	984	6	,	,	PUNCT
fnp-3528	984	7	z.	z.	PROPN
fnp-3528	984	8	r.	r.	PROPN
fnp-3528	984	9	;	;	PUNCT
fnp-3528	984	10	chou	chou	PROPN
fnp-3528	984	11	,	,	PUNCT
fnp-3528	984	12	c.	c.	PROPN
fnp-3528	984	13	f.	f.	PROPN
fnp-3528	984	14	;	;	PUNCT
fnp-3528	984	15	liang	liang	PROPN
fnp-3528	984	16	,	,	PUNCT
fnp-3528	984	17	y.	y.	PROPN
fnp-3528	984	18	y.	y.	PROPN
fnp-3528	984	19	;	;	PUNCT
fnp-3528	984	20	gu	gu	NOUN
fnp-3528	984	21	,	,	PUNCT
fnp-3528	984	22	y.	y.	PROPN
fnp-3528	984	23	;	;	PUNCT
fnp-3528	984	24	ma	ma	PROPN
fnp-3528	984	25	,	,	PUNCT
fnp-3528	984	26	h.	h.	PROPN
fnp-3528	984	27	p.	p.	PROPN
fnp-3528	984	28	cyclosporine	cyclosporine	PROPN
fnp-3528	984	29	stimulates	stimulate	VERB
fnp-3528	984	30	the	the	DET
fnp-3528	984	31	renal	renal	ADJ
fnp-3528	984	32	epithelial	epithelial	ADJ
fnp-3528	984	33	sodium	sodium	NOUN
fnp-3528	984	34	channel	channel	NOUN
fnp-3528	984	35	by	by	ADP
fnp-3528	984	36	elevating	elevate	VERB
fnp-3528	984	37	cholesterol	cholesterol	NOUN
fnp-3528	984	38	.	.	PUNCT
fnp-3528	985	1	am	be	AUX
fnp-3528	985	2	j	j	PROPN
fnp-3528	985	3	physiol	physiol	PROPN
fnp-3528	985	4	renal	renal	PROPN
fnp-3528	985	5	physiol	physiol	PROPN
fnp-3528	985	6	2009	2009	NUM
fnp-3528	985	7	,	,	PUNCT
fnp-3528	985	8	296	296	NUM
fnp-3528	985	9	,	,	PUNCT
fnp-3528	985	10	f284	f284	PROPN
fnp-3528	985	11	-	-	PUNCT
fnp-3528	985	12	90	90	PROPN
fnp-3528	985	13	.	.	PUNCT
fnp-3528	986	1	pirillo	pirillo	PROPN
fnp-3528	986	2	,	,	PUNCT
fnp-3528	986	3	a.	a.	NOUN
fnp-3528	986	4	;	;	PUNCT
fnp-3528	986	5	uboldi	uboldi	ADV
fnp-3528	986	6	,	,	PUNCT
fnp-3528	986	7	p.	p.	NOUN
fnp-3528	986	8	;	;	PUNCT
fnp-3528	986	9	pappalardo	pappalardo	PROPN
fnp-3528	986	10	,	,	PUNCT
fnp-3528	986	11	g.	g.	PROPN
fnp-3528	986	12	;	;	PUNCT
fnp-3528	986	13	kuhn	kuhn	PROPN
fnp-3528	986	14	,	,	PUNCT
fnp-3528	986	15	h.	h.	PROPN
fnp-3528	986	16	;	;	PUNCT
fnp-3528	986	17	catapano	catapano	PROPN
fnp-3528	986	18	,	,	PUNCT
fnp-3528	986	19	a.	a.	PROPN
fnp-3528	986	20	l.	l.	PROPN
fnp-3528	986	21	modification	modification	PROPN
fnp-3528	986	22	of	of	ADP
fnp-3528	986	23	hdl3	hdl3	NOUN
fnp-3528	986	24	by	by	ADP
fnp-3528	986	25	mild	mild	ADJ
fnp-3528	986	26	oxidative	oxidative	ADJ
fnp-3528	986	27	stress	stress	NOUN
fnp-3528	986	28	increases	increase	VERB
fnp-3528	986	29	atp	atp	NOUN
fnp-3528	986	30	-	-	PUNCT
fnp-3528	986	31	binding	bind	VERB
fnp-3528	986	32	cassette	cassette	NOUN
fnp-3528	986	33	transporter	transporter	NOUN
fnp-3528	986	34	1	1	NUM
fnp-3528	986	35	-	-	PUNCT
fnp-3528	986	36	mediated	mediate	VERB
fnp-3528	986	37	cholesterol	cholesterol	NOUN
fnp-3528	986	38	efflux	efflux	NOUN
fnp-3528	986	39	.	.	PUNCT
fnp-3528	987	1	cardiovasc	cardiovasc	PROPN
fnp-3528	987	2	res	re	VERB
fnp-3528	987	3	2007	2007	NUM
fnp-3528	987	4	,	,	PUNCT
fnp-3528	987	5	75	75	NUM
fnp-3528	987	6	,	,	PUNCT
fnp-3528	987	7	566	566	NUM
fnp-3528	987	8	-	-	SYM
fnp-3528	987	9	74	74	NUM
fnp-3528	987	10	.	.	PUNCT
fnp-3528	987	11	nofer	nofer	PROPN
fnp-3528	987	12	,	,	PUNCT
fnp-3528	987	13	j.	j.	PROPN
fnp-3528	987	14	r.	r.	PROPN
fnp-3528	987	15	;	;	PUNCT
fnp-3528	987	16	remaley	remaley	PROPN
fnp-3528	987	17	,	,	PUNCT
fnp-3528	987	18	a.	a.	NOUN
fnp-3528	987	19	t.	t.	PROPN
fnp-3528	987	20	;	;	PUNCT
fnp-3528	987	21	feuerborn	feuerborn	VERB
fnp-3528	987	22	,	,	PUNCT
fnp-3528	987	23	r.	r.	PROPN
fnp-3528	987	24	;	;	PUNCT
fnp-3528	987	25	wolinnska	wolinnska	PROPN
fnp-3528	987	26	,	,	PUNCT
fnp-3528	987	27	i.	i.	PROPN
fnp-3528	987	28	;	;	PUNCT
fnp-3528	987	29	engel	engel	PROPN
fnp-3528	987	30	,	,	PUNCT
fnp-3528	987	31	t.	t.	PROPN
fnp-3528	987	32	;	;	PUNCT
fnp-3528	987	33	von	von	PROPN
fnp-3528	987	34	eckardstein	eckardstein	PROPN
fnp-3528	987	35	,	,	PUNCT
fnp-3528	987	36	a.	a.	NOUN
fnp-3528	987	37	;	;	PUNCT
fnp-3528	987	38	assmann	assmann	PROPN
fnp-3528	987	39	,	,	PUNCT
fnp-3528	987	40	g.	g.	PROPN
fnp-3528	987	41	apolipoprotein	apolipoprotein	VERB
fnp-3528	987	42	a	a	X
fnp-3528	987	43	-	-	PUNCT
fnp-3528	987	44	i	i	PRON
fnp-3528	987	45	activates	activate	VERB
fnp-3528	987	46	cdc42	cdc42	PROPN
fnp-3528	987	47	signaling	signal	VERB
fnp-3528	987	48	through	through	ADP
fnp-3528	987	49	the	the	DET
fnp-3528	987	50	abca1	abca1	NOUN
fnp-3528	987	51	transporter	transporter	NOUN
fnp-3528	987	52	.	.	PUNCT
fnp-3528	988	1	j	j	PROPN
fnp-3528	988	2	lipid	lipid	PROPN
fnp-3528	988	3	res	re	NOUN
fnp-3528	988	4	2006	2006	NUM
fnp-3528	988	5	,	,	PUNCT
fnp-3528	988	6	47	47	NUM
fnp-3528	988	7	,	,	PUNCT
fnp-3528	988	8	794	794	NUM
fnp-3528	988	9	-	-	SYM
fnp-3528	988	10	803	803	NUM
fnp-3528	988	11	.	.	PUNCT
fnp-3528	989	1	alder	alder	NOUN
fnp-3528	989	2	-	-	PUNCT
fnp-3528	989	3	baerens	baeren	NOUN
fnp-3528	989	4	,	,	PUNCT
fnp-3528	989	5	n.	n.	NOUN
fnp-3528	989	6	;	;	PUNCT
fnp-3528	989	7	muller	muller	NOUN
fnp-3528	989	8	,	,	PUNCT
fnp-3528	989	9	p.	p.	PROPN
fnp-3528	989	10	;	;	PUNCT
fnp-3528	989	11	pohl	pohl	PROPN
fnp-3528	989	12	,	,	PUNCT
fnp-3528	989	13	a.	a.	NOUN
fnp-3528	989	14	;	;	PUNCT
fnp-3528	989	15	korte	korte	NOUN
fnp-3528	989	16	,	,	PUNCT
fnp-3528	989	17	t.	t.	PROPN
fnp-3528	989	18	;	;	PUNCT
fnp-3528	989	19	hamon	hamon	NOUN
fnp-3528	989	20	,	,	PUNCT
fnp-3528	989	21	y.	y.	PROPN
fnp-3528	989	22	;	;	PUNCT
fnp-3528	989	23	chimini	chimini	PROPN
fnp-3528	989	24	,	,	PUNCT
fnp-3528	989	25	g.	g.	PROPN
fnp-3528	989	26	;	;	PUNCT
fnp-3528	989	27	pomorski	pomorski	PROPN
fnp-3528	989	28	,	,	PUNCT
fnp-3528	989	29	t.	t.	PROPN
fnp-3528	989	30	;	;	PUNCT
fnp-3528	989	31	herrmann	herrmann	PROPN
fnp-3528	989	32	,	,	PUNCT
fnp-3528	989	33	a.	a.	PROPN
fnp-3528	989	34	headgroup	headgroup	NOUN
fnp-3528	989	35	-	-	PUNCT
fnp-3528	989	36	specific	specific	ADJ
fnp-3528	989	37	exposure	exposure	NOUN
fnp-3528	989	38	of	of	ADP
fnp-3528	989	39	phospholipids	phospholipid	NOUN
fnp-3528	989	40	in	in	ADP
fnp-3528	989	41	abca1	abca1	NOUN
fnp-3528	989	42	-	-	PUNCT
fnp-3528	989	43	expressing	express	VERB
fnp-3528	989	44	cells	cell	NOUN
fnp-3528	989	45	.	.	PUNCT
fnp-3528	990	1	j	j	PROPN
fnp-3528	990	2	biol	biol	PROPN
fnp-3528	990	3	chem	chem	NOUN
fnp-3528	990	4	2005	2005	NUM
fnp-3528	990	5	,	,	PUNCT
fnp-3528	990	6	280	280	NUM
fnp-3528	990	7	,	,	PUNCT
fnp-3528	990	8	26321	26321	NUM
fnp-3528	990	9	-	-	SYM
fnp-3528	990	10	9	9	NUM
fnp-3528	990	11	.	.	PUNCT
fnp-3528	990	12	field	field	NOUN
fnp-3528	990	13	,	,	PUNCT
fnp-3528	990	14	f.	f.	PROPN
fnp-3528	990	15	j.	j.	PROPN
fnp-3528	990	16	;	;	PUNCT
fnp-3528	990	17	born	bear	VERB
fnp-3528	990	18	,	,	PUNCT
fnp-3528	990	19	e.	e.	PROPN
fnp-3528	990	20	;	;	PUNCT
fnp-3528	990	21	mathur	mathur	PROPN
fnp-3528	990	22	,	,	PUNCT
fnp-3528	990	23	s.	s.	PROPN
fnp-3528	990	24	n.	n.	PROPN
fnp-3528	990	25	lxr	lxr	PROPN
fnp-3528	990	26	/	/	SYM
fnp-3528	990	27	rxr	rxr	PROPN
fnp-3528	990	28	ligand	ligand	PROPN
fnp-3528	990	29	activation	activation	NOUN
fnp-3528	990	30	enhances	enhance	VERB
fnp-3528	990	31	basolateral	basolateral	ADJ
fnp-3528	990	32	efflux	efflux	NOUN
fnp-3528	990	33	of	of	ADP
fnp-3528	990	34	beta	beta	NOUN
fnp-3528	990	35	-	-	PUNCT
fnp-3528	990	36	sitosterol	sitosterol	NOUN
fnp-3528	990	37	in	in	ADP
fnp-3528	990	38	caco-2	caco-2	NUM
fnp-3528	990	39	cells	cell	NOUN
fnp-3528	990	40	.	.	PUNCT
fnp-3528	991	1	j	j	PROPN
fnp-3528	991	2	lipid	lipid	PROPN
fnp-3528	991	3	res	re	NOUN
fnp-3528	991	4	2004	2004	NUM
fnp-3528	991	5	,	,	PUNCT
fnp-3528	991	6	45	45	NUM
fnp-3528	991	7	,	,	PUNCT
fnp-3528	991	8	905	905	NUM
fnp-3528	991	9	-	-	SYM
fnp-3528	991	10	13	13	NUM
fnp-3528	991	11	.	.	PUNCT
fnp-3528	992	1	reddy	reddy	PROPN
fnp-3528	992	2	,	,	PUNCT
fnp-3528	992	3	s.	s.	PROPN
fnp-3528	992	4	t.	t.	PROPN
fnp-3528	992	5	;	;	PUNCT
fnp-3528	992	6	hama	hama	PROPN
fnp-3528	992	7	,	,	PUNCT
fnp-3528	992	8	s.	s.	PROPN
fnp-3528	992	9	;	;	PUNCT
fnp-3528	992	10	ng	ng	PROPN
fnp-3528	992	11	,	,	PUNCT
fnp-3528	992	12	c.	c.	PROPN
fnp-3528	992	13	;	;	PUNCT
fnp-3528	992	14	grijalva	grijalva	PROPN
fnp-3528	992	15	,	,	PUNCT
fnp-3528	992	16	v.	v.	PROPN
fnp-3528	992	17	;	;	PUNCT
fnp-3528	992	18	navab	navab	PROPN
fnp-3528	992	19	,	,	PUNCT
fnp-3528	992	20	m.	m.	NOUN
fnp-3528	992	21	;	;	PUNCT
fnp-3528	992	22	fogelman	fogelman	ADJ
fnp-3528	992	23	,	,	PUNCT
fnp-3528	992	24	a.	a.	PROPN
fnp-3528	992	25	m.	m.	PROPN
fnp-3528	992	26	atp	atp	PROPN
fnp-3528	992	27	-	-	PUNCT
fnp-3528	992	28	binding	bind	VERB
fnp-3528	992	29	cassette	cassette	NOUN
fnp-3528	992	30	transporter	transporter	NOUN
fnp-3528	992	31	1	1	NUM
fnp-3528	992	32	participates	participate	VERB
fnp-3528	992	33	in	in	ADP
fnp-3528	992	34	ldl	ldl	NOUN
fnp-3528	992	35	oxidation	oxidation	NOUN
fnp-3528	992	36	by	by	ADP
fnp-3528	992	37	artery	artery	NOUN
fnp-3528	992	38	wall	wall	NOUN
fnp-3528	992	39	cells	cell	NOUN
fnp-3528	992	40	.	.	PUNCT
fnp-3528	993	1	arterioscler	arterioscler	PROPN
fnp-3528	993	2	thromb	thromb	PROPN
fnp-3528	993	3	vasc	vasc	PROPN
fnp-3528	993	4	biol	biol	PROPN
fnp-3528	993	5	2002	2002	NUM
fnp-3528	993	6	,	,	PUNCT
fnp-3528	993	7	22	22	NUM
fnp-3528	993	8	,	,	PUNCT
fnp-3528	993	9	1877	1877	NUM
fnp-3528	993	10	-	-	SYM
fnp-3528	993	11	83	83	NUM
fnp-3528	993	12	.	.	PUNCT
fnp-3528	994	1	murthy	murthy	PROPN
fnp-3528	994	2	,	,	PUNCT
fnp-3528	994	3	s.	s.	PROPN
fnp-3528	994	4	;	;	PUNCT
fnp-3528	994	5	born	bear	VERB
fnp-3528	994	6	,	,	PUNCT
fnp-3528	994	7	e.	e.	PROPN
fnp-3528	994	8	;	;	PUNCT
fnp-3528	994	9	mathur	mathur	PROPN
fnp-3528	994	10	,	,	PUNCT
fnp-3528	994	11	s.	s.	PROPN
fnp-3528	994	12	n.	n.	PROPN
fnp-3528	994	13	;	;	PUNCT
fnp-3528	994	14	field	field	NOUN
fnp-3528	994	15	,	,	PUNCT
fnp-3528	994	16	f.	f.	PROPN
fnp-3528	994	17	j.	j.	PROPN
fnp-3528	994	18	lxr	lxr	PROPN
fnp-3528	994	19	/	/	SYM
fnp-3528	994	20	rxr	rxr	PROPN
fnp-3528	994	21	activation	activation	NOUN
fnp-3528	994	22	enhances	enhance	VERB
fnp-3528	994	23	basolateral	basolateral	ADJ
fnp-3528	994	24	efflux	efflux	NOUN
fnp-3528	994	25	of	of	ADP
fnp-3528	994	26	cholesterol	cholesterol	NOUN
fnp-3528	994	27	in	in	ADP
fnp-3528	994	28	caco-2	caco-2	NUM
fnp-3528	994	29	cells	cell	NOUN
fnp-3528	994	30	.	.	PUNCT
fnp-3528	995	1	j	j	PROPN
fnp-3528	995	2	lipid	lipid	PROPN
fnp-3528	995	3	res	re	NOUN
fnp-3528	995	4	2002	2002	NUM
fnp-3528	995	5	,	,	PUNCT
fnp-3528	995	6	43	43	NUM
fnp-3528	995	7	,	,	PUNCT
fnp-3528	995	8	1054	1054	NUM
fnp-3528	995	9	-	-	SYM
fnp-3528	995	10	64	64	NUM
fnp-3528	995	11	.	.	PUNCT
fnp-3528	996	1	huang	huang	PROPN
fnp-3528	996	2	,	,	PUNCT
fnp-3528	996	3	z.	z.	PROPN
fnp-3528	996	4	h.	h.	PROPN
fnp-3528	996	5	;	;	PUNCT
fnp-3528	996	6	lin	lin	PROPN
fnp-3528	996	7	,	,	PUNCT
fnp-3528	996	8	c.	c.	PROPN
fnp-3528	996	9	y.	y.	PROPN
fnp-3528	996	10	;	;	PUNCT
fnp-3528	996	11	oram	oram	PROPN
fnp-3528	996	12	,	,	PUNCT
fnp-3528	996	13	j.	j.	PROPN
fnp-3528	996	14	f.	f.	PROPN
fnp-3528	996	15	;	;	PUNCT
fnp-3528	996	16	mazzone	mazzone	NOUN
fnp-3528	996	17	,	,	PUNCT
fnp-3528	996	18	t.	t.	NOUN
fnp-3528	996	19	sterol	sterol	NOUN
fnp-3528	996	20	efflux	efflux	NOUN
fnp-3528	996	21	mediated	mediate	VERB
fnp-3528	996	22	by	by	ADP
fnp-3528	996	23	endogenous	endogenous	ADJ
fnp-3528	996	24	macrophage	macrophage	NOUN
fnp-3528	996	25	apoe	apoe	NOUN
fnp-3528	996	26	expression	expression	NOUN
fnp-3528	996	27	is	be	AUX
fnp-3528	996	28	independent	independent	ADJ
fnp-3528	996	29	of	of	ADP
fnp-3528	996	30	abca1	abca1	NOUN
fnp-3528	996	31	.	.	PUNCT
fnp-3528	997	1	arterioscler	arterioscler	PROPN
fnp-3528	997	2	thromb	thromb	PROPN
fnp-3528	997	3	vasc	vasc	PROPN
fnp-3528	997	4	biol	biol	PROPN
fnp-3528	997	5	2001	2001	NUM
fnp-3528	997	6	,	,	PUNCT
fnp-3528	997	7	21	21	NUM
fnp-3528	997	8	,	,	PUNCT
fnp-3528	997	9	2019	2019	NUM
fnp-3528	997	10	-	-	SYM
fnp-3528	997	11	25	25	NUM
fnp-3528	997	12	.	.	PUNCT
fnp-3528	998	1	von	von	PROPN
fnp-3528	998	2	eckardstein	eckardstein	PROPN
fnp-3528	998	3	,	,	PUNCT
fnp-3528	998	4	a.	a.	NOUN
fnp-3528	998	5	;	;	PUNCT
fnp-3528	998	6	langer	langer	PROPN
fnp-3528	998	7	,	,	PUNCT
fnp-3528	998	8	c.	c.	PROPN
fnp-3528	998	9	;	;	PUNCT
fnp-3528	998	10	engel	engel	PROPN
fnp-3528	998	11	,	,	PUNCT
fnp-3528	998	12	t.	t.	PROPN
fnp-3528	998	13	;	;	PUNCT
fnp-3528	998	14	schaukal	schaukal	NOUN
fnp-3528	998	15	,	,	PUNCT
fnp-3528	998	16	i.	i.	PROPN
fnp-3528	998	17	;	;	PUNCT
fnp-3528	998	18	cignarella	cignarella	NOUN
fnp-3528	998	19	,	,	PUNCT
fnp-3528	998	20	a.	a.	NOUN
fnp-3528	998	21	;	;	PUNCT
fnp-3528	998	22	reinhardt	reinhardt	PROPN
fnp-3528	998	23	,	,	PUNCT
fnp-3528	998	24	j.	j.	PROPN
fnp-3528	998	25	;	;	PUNCT
fnp-3528	998	26	lorkowski	lorkowski	PROPN
fnp-3528	998	27	,	,	PUNCT
fnp-3528	998	28	s.	s.	PROPN
fnp-3528	998	29	;	;	PUNCT
fnp-3528	998	30	li	li	PROPN
fnp-3528	998	31	,	,	PUNCT
fnp-3528	998	32	z.	z.	PROPN
fnp-3528	998	33	;	;	PUNCT
fnp-3528	998	34	zhou	zhou	PROPN
fnp-3528	998	35	,	,	PUNCT
fnp-3528	998	36	x.	x.	PROPN
fnp-3528	998	37	;	;	PUNCT
fnp-3528	998	38	cullen	cullen	VERB
fnp-3528	998	39	,	,	PUNCT
fnp-3528	998	40	p.	p.	PROPN
fnp-3528	998	41	;	;	PUNCT
fnp-3528	998	42	assmann	assmann	PROPN
fnp-3528	998	43	,	,	PUNCT
fnp-3528	998	44	g.	g.	PROPN
fnp-3528	998	45	atp	atp	PROPN
fnp-3528	998	46	binding	bind	VERB
fnp-3528	998	47	cassette	cassette	NOUN
fnp-3528	998	48	transporter	transporter	NOUN
fnp-3528	998	49	abca1	abca1	NOUN
fnp-3528	998	50	modulates	modulate	VERB
fnp-3528	998	51	the	the	DET
fnp-3528	998	52	secretion	secretion	NOUN
fnp-3528	998	53	of	of	ADP
fnp-3528	998	54	apolipoprotein	apolipoprotein	ADJ
fnp-3528	998	55	e	e	PROPN
fnp-3528	998	56	from	from	ADP
fnp-3528	998	57	human	human	ADJ
fnp-3528	998	58	monocyte	monocyte	NOUN
fnp-3528	998	59	-	-	PUNCT
fnp-3528	998	60	derived	derive	VERB
fnp-3528	998	61	macrophages	macrophage	NOUN
fnp-3528	998	62	.	.	PUNCT
fnp-3528	999	1	faseb	faseb	PROPN
fnp-3528	999	2	j	j	PROPN
fnp-3528	999	3	2001	2001	NUM
fnp-3528	999	4	,	,	PUNCT
fnp-3528	999	5	15	15	NUM
fnp-3528	999	6	,	,	PUNCT
fnp-3528	999	7	1555	1555	NUM
fnp-3528	999	8	-	-	SYM
fnp-3528	999	9	61	61	NUM
fnp-3528	999	10	.	.	PUNCT
fnp-3528	1000	1	wang	wang	PROPN
fnp-3528	1000	2	,	,	PUNCT
fnp-3528	1000	3	n.	n.	PROPN
fnp-3528	1000	4	;	;	PUNCT
fnp-3528	1000	5	silver	silver	NOUN
fnp-3528	1000	6	,	,	PUNCT
fnp-3528	1000	7	d.	d.	PROPN
fnp-3528	1000	8	l.	l.	PROPN
fnp-3528	1000	9	;	;	PUNCT
fnp-3528	1000	10	thiele	thiele	PROPN
fnp-3528	1000	11	,	,	PUNCT
fnp-3528	1000	12	c.	c.	PROPN
fnp-3528	1000	13	;	;	PUNCT
fnp-3528	1000	14	tall	tall	ADJ
fnp-3528	1000	15	,	,	PUNCT
fnp-3528	1000	16	a.	a.	PROPN
fnp-3528	1000	17	r.	r.	PROPN
fnp-3528	1000	18	atp	atp	PROPN
fnp-3528	1000	19	-	-	PUNCT
fnp-3528	1000	20	binding	bind	VERB
fnp-3528	1000	21	cassette	cassette	NOUN
fnp-3528	1000	22	transporter	transporter	NOUN
fnp-3528	1000	23	a1	a1	NOUN
fnp-3528	1000	24	(	(	PUNCT
fnp-3528	1000	25	abca1	abca1	NOUN
fnp-3528	1000	26	)	)	PUNCT
fnp-3528	1000	27	functions	function	NOUN
fnp-3528	1000	28	as	as	ADP
fnp-3528	1000	29	a	a	DET
fnp-3528	1000	30	cholesterol	cholesterol	NOUN
fnp-3528	1000	31	efflux	efflux	VERB
fnp-3528	1000	32	regulatory	regulatory	ADJ
fnp-3528	1000	33	protein	protein	NOUN
fnp-3528	1000	34	.	.	PUNCT
fnp-3528	1001	1	j	j	PROPN
fnp-3528	1001	2	biol	biol	PROPN
fnp-3528	1001	3	chem	chem	NOUN
fnp-3528	1001	4	2001	2001	NUM
fnp-3528	1001	5	,	,	PUNCT
fnp-3528	1001	6	276	276	NUM
fnp-3528	1001	7	,	,	PUNCT
fnp-3528	1001	8	23742	23742	NUM
fnp-3528	1001	9	-	-	SYM
fnp-3528	1001	10	7	7	NUM
fnp-3528	1001	11	.	.	NUM
fnp-3528	1001	12	chinetti	chinetti	PROPN
fnp-3528	1001	13	,	,	PUNCT
fnp-3528	1001	14	g.	g.	PROPN
fnp-3528	1001	15	;	;	PUNCT
fnp-3528	1001	16	lestavel	lestavel	PROPN
fnp-3528	1001	17	,	,	PUNCT
fnp-3528	1001	18	s.	s.	PROPN
fnp-3528	1001	19	;	;	PUNCT
fnp-3528	1001	20	bocher	bocher	ADV
fnp-3528	1001	21	,	,	PUNCT
fnp-3528	1001	22	v.	v.	PROPN
fnp-3528	1001	23	;	;	PUNCT
fnp-3528	1001	24	remaley	remaley	PROPN
fnp-3528	1001	25	,	,	PUNCT
fnp-3528	1001	26	a.	a.	NOUN
fnp-3528	1001	27	t.	t.	PROPN
fnp-3528	1001	28	;	;	PUNCT
fnp-3528	1001	29	neve	neve	PROPN
fnp-3528	1001	30	,	,	PUNCT
fnp-3528	1001	31	b.	b.	PROPN
fnp-3528	1001	32	;	;	PUNCT
fnp-3528	1001	33	torra	torra	PROPN
fnp-3528	1001	34	,	,	PUNCT
fnp-3528	1001	35	i.	i.	PROPN
fnp-3528	1001	36	p.	p.	PROPN
fnp-3528	1001	37	;	;	PUNCT
fnp-3528	1001	38	teissier	teissier	NOUN
fnp-3528	1001	39	,	,	PUNCT
fnp-3528	1001	40	e.	e.	PROPN
fnp-3528	1001	41	;	;	PUNCT
fnp-3528	1001	42	minnich	minnich	PROPN
fnp-3528	1001	43	,	,	PUNCT
fnp-3528	1001	44	a.	a.	NOUN
fnp-3528	1001	45	;	;	PUNCT
fnp-3528	1001	46	jaye	jaye	PROPN
fnp-3528	1001	47	,	,	PUNCT
fnp-3528	1001	48	m.	m.	NOUN
fnp-3528	1001	49	;	;	PUNCT
fnp-3528	1001	50	duverger	duverger	NOUN
fnp-3528	1001	51	,	,	PUNCT
fnp-3528	1001	52	n.	n.	NOUN
fnp-3528	1001	53	;	;	PUNCT
fnp-3528	1001	54	brewer	brewer	PROPN
fnp-3528	1001	55	,	,	PUNCT
fnp-3528	1001	56	h.	h.	PROPN
fnp-3528	1001	57	b.	b.	PROPN
fnp-3528	1001	58	;	;	PUNCT
fnp-3528	1001	59	fruchart	fruchart	PROPN
fnp-3528	1001	60	,	,	PUNCT
fnp-3528	1001	61	j.	j.	PROPN
fnp-3528	1001	62	c.	c.	PROPN
fnp-3528	1001	63	;	;	PUNCT
fnp-3528	1001	64	clavey	clavey	NOUN
fnp-3528	1001	65	,	,	PUNCT
fnp-3528	1001	66	v.	v.	PROPN
fnp-3528	1001	67	;	;	PUNCT
fnp-3528	1001	68	staels	stael	NOUN
fnp-3528	1001	69	,	,	PUNCT
fnp-3528	1001	70	b.	b.	PROPN
fnp-3528	1001	71	ppar	ppar	NOUN
fnp-3528	1001	72	-	-	PUNCT
fnp-3528	1001	73	alpha	alpha	NOUN
fnp-3528	1001	74	and	and	CCONJ
fnp-3528	1001	75	ppar	ppar	NOUN
fnp-3528	1001	76	-	-	PUNCT
fnp-3528	1001	77	gamma	gamma	NOUN
fnp-3528	1001	78	activators	activator	NOUN
fnp-3528	1001	79	induce	induce	VERB
fnp-3528	1001	80	cholesterol	cholesterol	NOUN
fnp-3528	1001	81	removal	removal	NOUN
fnp-3528	1001	82	from	from	ADP
fnp-3528	1001	83	human	human	ADJ
fnp-3528	1001	84	macrophage	macrophage	NOUN
fnp-3528	1001	85	foam	foam	NOUN
fnp-3528	1001	86	cells	cell	NOUN
fnp-3528	1001	87	through	through	ADP
fnp-3528	1001	88	stimulation	stimulation	NOUN
fnp-3528	1001	89	of	of	ADP
fnp-3528	1001	90	the	the	DET
fnp-3528	1001	91	abca1	abca1	NOUN
fnp-3528	1001	92	pathway	pathway	NOUN
fnp-3528	1001	93	.	.	PUNCT
fnp-3528	1002	1	nat	nat	PROPN
fnp-3528	1002	2	med	med	PROPN
fnp-3528	1002	3	2001	2001	NUM
fnp-3528	1002	4	,	,	PUNCT
fnp-3528	1002	5	7	7	NUM
fnp-3528	1002	6	,	,	PUNCT
fnp-3528	1002	7	53	53	NUM
fnp-3528	1002	8	-	-	SYM
fnp-3528	1002	9	8	8	NUM
fnp-3528	1002	10	.	.	PUNCT
fnp-3528	1003	1	fielding	field	VERB
fnp-3528	1003	2	,	,	PUNCT
fnp-3528	1003	3	p.	p.	PROPN
fnp-3528	1003	4	e.	e.	PROPN
fnp-3528	1003	5	;	;	PUNCT
fnp-3528	1003	6	nagao	nagao	ADV
fnp-3528	1003	7	,	,	PUNCT
fnp-3528	1003	8	k.	k.	PROPN
fnp-3528	1003	9	;	;	PUNCT
fnp-3528	1003	10	hakamata	hakamata	PROPN
fnp-3528	1003	11	,	,	PUNCT
fnp-3528	1003	12	h.	h.	PROPN
fnp-3528	1003	13	;	;	PUNCT
fnp-3528	1003	14	chimini	chimini	PROPN
fnp-3528	1003	15	,	,	PUNCT
fnp-3528	1003	16	g.	g.	PROPN
fnp-3528	1003	17	;	;	PUNCT
fnp-3528	1003	18	fielding	field	VERB
fnp-3528	1003	19	,	,	PUNCT
fnp-3528	1004	1	c.	c.	PROPN
fnp-3528	1004	2	j.	j.	PROPN
fnp-3528	1005	1	a	a	DET
fnp-3528	1005	2	two	two	NUM
fnp-3528	1005	3	-	-	PUNCT
fnp-3528	1005	4	step	step	NOUN
fnp-3528	1005	5	mechanism	mechanism	NOUN
fnp-3528	1005	6	for	for	ADP
fnp-3528	1005	7	free	free	ADJ
fnp-3528	1005	8	cholesterol	cholesterol	NOUN
fnp-3528	1005	9	and	and	CCONJ
fnp-3528	1005	10	phospholipid	phospholipid	NOUN
fnp-3528	1005	11	efflux	efflux	VERB
fnp-3528	1005	12	from	from	ADP
fnp-3528	1005	13	human	human	ADJ
fnp-3528	1005	14	vascular	vascular	ADJ
fnp-3528	1005	15	cells	cell	NOUN
fnp-3528	1005	16	to	to	PART
fnp-3528	1005	17	apolipoprotein	apolipoprotein	VERB
fnp-3528	1005	18	a-1	a-1	PROPN
fnp-3528	1005	19	.	.	PUNCT
fnp-3528	1006	1	biochemistry	biochemistry	PROPN
fnp-3528	1006	2	2000	2000	NUM
fnp-3528	1006	3	,	,	PUNCT
fnp-3528	1006	4	39	39	NUM
fnp-3528	1006	5	,	,	PUNCT
fnp-3528	1006	6	14113	14113	NUM
fnp-3528	1006	7	-	-	SYM
fnp-3528	1006	8	20	20	NUM
fnp-3528	1006	9	.	.	PUNCT
fnp-3528	1006	10	nieland	nieland	NOUN
fnp-3528	1006	11	,	,	PUNCT
fnp-3528	1006	12	t.	t.	PROPN
fnp-3528	1006	13	j.	j.	PROPN
fnp-3528	1006	14	;	;	PUNCT
fnp-3528	1006	15	chroni	chroni	PROPN
fnp-3528	1006	16	,	,	PUNCT
fnp-3528	1006	17	a.	a.	PROPN
fnp-3528	1006	18	;	;	PUNCT
fnp-3528	1006	19	fitzgerald	fitzgerald	PROPN
fnp-3528	1006	20	,	,	PUNCT
fnp-3528	1006	21	m.	m.	NOUN
fnp-3528	1006	22	l.	l.	PROPN
fnp-3528	1006	23	;	;	PUNCT
fnp-3528	1006	24	maliga	maliga	PROPN
fnp-3528	1006	25	,	,	PUNCT
fnp-3528	1006	26	z.	z.	PROPN
fnp-3528	1006	27	;	;	PUNCT
fnp-3528	1006	28	zannis	zannis	X
fnp-3528	1006	29	,	,	PUNCT
fnp-3528	1006	30	v.	v.	PROPN
fnp-3528	1006	31	i.	i.	PROPN
fnp-3528	1006	32	;	;	PUNCT
fnp-3528	1006	33	kirchhausen	kirchhausen	PROPN
fnp-3528	1006	34	,	,	PUNCT
fnp-3528	1006	35	t.	t.	PROPN
fnp-3528	1006	36	;	;	PUNCT
fnp-3528	1006	37	krieger	krieger	PROPN
fnp-3528	1006	38	,	,	PUNCT
fnp-3528	1006	39	m.	m.	NOUN
fnp-3528	1006	40	cross	cross	NOUN
fnp-3528	1006	41	-	-	NOUN
fnp-3528	1006	42	inhibition	inhibition	NOUN
fnp-3528	1006	43	of	of	ADP
fnp-3528	1006	44	sr	sr	PROPN
fnp-3528	1006	45	-	-	PUNCT
fnp-3528	1006	46	biand	biand	NOUN
fnp-3528	1006	47	abca1	abca1	NOUN
fnp-3528	1006	48	-	-	PUNCT
fnp-3528	1006	49	mediated	mediate	VERB
fnp-3528	1006	50	cholesterol	cholesterol	NOUN
fnp-3528	1006	51	transport	transport	NOUN
fnp-3528	1006	52	by	by	ADP
fnp-3528	1006	53	the	the	DET
fnp-3528	1006	54	small	small	ADJ
fnp-3528	1006	55	molecules	molecule	NOUN
fnp-3528	1006	56	blt-4	blt-4	PUNCT
fnp-3528	1006	57	and	and	CCONJ
fnp-3528	1006	58	glyburide	glyburide	NOUN
fnp-3528	1006	59	.	.	PUNCT
fnp-3528	1007	1	j	j	PROPN
fnp-3528	1007	2	lipid	lipid	PROPN
fnp-3528	1007	3	res	re	NOUN
fnp-3528	1007	4	2004	2004	NUM
fnp-3528	1007	5	,	,	PUNCT
fnp-3528	1007	6	45	45	NUM
fnp-3528	1007	7	,	,	PUNCT
fnp-3528	1007	8	1256	1256	NUM
fnp-3528	1007	9	-	-	SYM
fnp-3528	1007	10	65	65	NUM
fnp-3528	1007	11	.	.	PUNCT
fnp-3528	1008	1	lewandowski	lewandowski	PROPN
fnp-3528	1008	2	,	,	PUNCT
fnp-3528	1008	3	c.	c.	PROPN
fnp-3528	1008	4	t.	t.	PROPN
fnp-3528	1008	5	;	;	PUNCT
fnp-3528	1008	6	khan	khan	PROPN
fnp-3528	1008	7	,	,	PUNCT
fnp-3528	1008	8	m.	m.	PROPN
fnp-3528	1008	9	w.	w.	PROPN
fnp-3528	1008	10	;	;	PUNCT
fnp-3528	1008	11	benaissa	benaissa	NOUN
fnp-3528	1008	12	,	,	PUNCT
fnp-3528	1008	13	m.	m.	NOUN
fnp-3528	1008	14	;	;	PUNCT
fnp-3528	1008	15	dubrovskyi	dubrovskyi	PROPN
fnp-3528	1008	16	,	,	PUNCT
fnp-3528	1008	17	o.	o.	PROPN
fnp-3528	1008	18	;	;	PUNCT
fnp-3528	1008	19	ackerman	ackerman	NOUN
fnp-3528	1008	20	-	-	PUNCT
fnp-3528	1008	21	berrier	berrier	NOUN
fnp-3528	1008	22	,	,	PUNCT
fnp-3528	1008	23	m.	m.	NOUN
fnp-3528	1008	24	;	;	PUNCT
fnp-3528	1008	25	ladu	ladu	ADJ
fnp-3528	1008	26	,	,	PUNCT
fnp-3528	1008	27	m.	m.	NOUN
fnp-3528	1008	28	j.	j.	PROPN
fnp-3528	1008	29	;	;	PUNCT
fnp-3528	1008	30	layden	layden	PROPN
fnp-3528	1008	31	,	,	PUNCT
fnp-3528	1008	32	b.	b.	PROPN
fnp-3528	1008	33	t.	t.	PROPN
fnp-3528	1008	34	;	;	PUNCT
fnp-3528	1008	35	thatcher	thatcher	PROPN
fnp-3528	1008	36	,	,	PUNCT
fnp-3528	1008	37	g.	g.	PROPN
fnp-3528	1008	38	r.	r.	PROPN
fnp-3528	1008	39	j.	j.	PROPN
fnp-3528	1009	1	metabolomic	metabolomic	ADJ
fnp-3528	1009	2	analysis	analysis	NOUN
fnp-3528	1009	3	of	of	ADP
fnp-3528	1009	4	a	a	DET
fnp-3528	1009	5	selective	selective	ADJ
fnp-3528	1009	6	abca1	abca1	NOUN
fnp-3528	1009	7	inducer	inducer	NOUN
fnp-3528	1009	8	in	in	ADP
fnp-3528	1009	9	obesogenic	obesogenic	ADJ
fnp-3528	1009	10	challenge	challenge	NOUN
fnp-3528	1009	11	provides	provide	VERB
fnp-3528	1009	12	a	a	DET
fnp-3528	1009	13	rationale	rationale	NOUN
fnp-3528	1009	14	for	for	ADP
fnp-3528	1009	15	therapeutic	therapeutic	ADJ
fnp-3528	1009	16	development	development	NOUN
fnp-3528	1009	17	.	.	PUNCT
fnp-3528	1010	1	ebiomedicine	ebiomedicine	ADJ
fnp-3528	1010	2	2021	2021	NUM
fnp-3528	1010	3	,	,	PUNCT
fnp-3528	1010	4	66	66	NUM
fnp-3528	1010	5	,	,	PUNCT
fnp-3528	1010	6	103287	103287	NUM
fnp-3528	1010	7	.	.	PUNCT
fnp-3528	1011	1	wang	wang	PROPN
fnp-3528	1011	2	,	,	PUNCT
fnp-3528	1011	3	d.	d.	PROPN
fnp-3528	1011	4	;	;	PUNCT
fnp-3528	1011	5	hiebl	hiebl	PROPN
fnp-3528	1011	6	,	,	PUNCT
fnp-3528	1011	7	v.	v.	PROPN
fnp-3528	1011	8	;	;	PUNCT
fnp-3528	1011	9	schachner	schachner	NOUN
fnp-3528	1011	10	,	,	PUNCT
fnp-3528	1011	11	d.	d.	PROPN
fnp-3528	1011	12	;	;	PUNCT
fnp-3528	1011	13	ladurner	ladurner	ADJ
fnp-3528	1011	14	,	,	PUNCT
fnp-3528	1011	15	a.	a.	NOUN
fnp-3528	1011	16	;	;	PUNCT
fnp-3528	1011	17	heiss	heiss	PROPN
fnp-3528	1011	18	,	,	PUNCT
fnp-3528	1011	19	e.	e.	PROPN
fnp-3528	1011	20	h.	h.	PROPN
fnp-3528	1011	21	;	;	PUNCT
fnp-3528	1011	22	atanasov	atanasov	PROPN
fnp-3528	1011	23	,	,	PUNCT
fnp-3528	1011	24	a.	a.	NOUN
fnp-3528	1011	25	g.	g.	PROPN
fnp-3528	1011	26	;	;	PUNCT
fnp-3528	1011	27	dirsch	dirsch	PROPN
fnp-3528	1011	28	,	,	PUNCT
fnp-3528	1011	29	v.	v.	ADP
fnp-3528	1011	30	m.	m.	NOUN
fnp-3528	1011	31	soraphen	soraphen	PROPN
fnp-3528	1011	32	a	a	DET
fnp-3528	1011	33	enhances	enhance	VERB
fnp-3528	1011	34	macrophage	macrophage	ADJ
fnp-3528	1011	35	cholesterol	cholesterol	NOUN
fnp-3528	1011	36	efflux	efflux	NOUN
fnp-3528	1011	37	via	via	ADP
fnp-3528	1011	38	indirect	indirect	ADJ
fnp-3528	1011	39	lxr	lxr	NOUN
fnp-3528	1011	40	activation	activation	NOUN
fnp-3528	1011	41	and	and	CCONJ
fnp-3528	1011	42	abca1	abca1	NOUN
fnp-3528	1011	43	upregulation	upregulation	NOUN
fnp-3528	1011	44	.	.	PUNCT
fnp-3528	1012	1	biochem	biochem	PROPN
fnp-3528	1012	2	pharmacol	pharmacol	PROPN
fnp-3528	1012	3	2020	2020	NUM
fnp-3528	1012	4	,	,	PUNCT
fnp-3528	1012	5	177	177	NUM
fnp-3528	1012	6	,	,	PUNCT
fnp-3528	1012	7	114022	114022	NUM
fnp-3528	1012	8	.	.	PUNCT
fnp-3528	1013	1	quach	quach	NOUN
fnp-3528	1013	2	,	,	PUNCT
fnp-3528	1013	3	d.	d.	PROPN
fnp-3528	1013	4	;	;	PUNCT
fnp-3528	1013	5	vitali	vitali	PROPN
fnp-3528	1013	6	,	,	PUNCT
fnp-3528	1013	7	c.	c.	PROPN
fnp-3528	1013	8	;	;	PUNCT
fnp-3528	1013	9	la	la	PROPN
fnp-3528	1013	10	,	,	PUNCT
fnp-3528	1013	11	f.	f.	PROPN
fnp-3528	1013	12	m.	m.	PROPN
fnp-3528	1013	13	;	;	PUNCT
fnp-3528	1013	14	xiao	xiao	PROPN
fnp-3528	1013	15	,	,	PUNCT
fnp-3528	1013	16	a.	a.	NOUN
fnp-3528	1013	17	x.	x.	PROPN
fnp-3528	1013	18	;	;	PUNCT
fnp-3528	1013	19	millar	millar	PROPN
fnp-3528	1013	20	,	,	PUNCT
fnp-3528	1013	21	j.	j.	PROPN
fnp-3528	1013	22	s.	s.	PROPN
fnp-3528	1013	23	;	;	PUNCT
fnp-3528	1013	24	tang	tang	PROPN
fnp-3528	1013	25	,	,	PUNCT
fnp-3528	1013	26	c.	c.	PROPN
fnp-3528	1013	27	;	;	PUNCT
fnp-3528	1013	28	rader	rader	PROPN
fnp-3528	1013	29	,	,	PUNCT
fnp-3528	1013	30	d.	d.	PROPN
fnp-3528	1013	31	j.	j.	PROPN
fnp-3528	1013	32	;	;	PUNCT
fnp-3528	1013	33	phillips	phillips	PROPN
fnp-3528	1013	34	,	,	PUNCT
fnp-3528	1013	35	m.	m.	PROPN
fnp-3528	1013	36	c.	c.	PROPN
fnp-3528	1013	37	;	;	PUNCT
fnp-3528	1013	38	lyssenko	lyssenko	PROPN
fnp-3528	1013	39	,	,	PUNCT
fnp-3528	1013	40	n.	n.	PROPN
fnp-3528	1013	41	n.	n.	PROPN
fnp-3528	1013	42	cell	cell	NOUN
fnp-3528	1013	43	lipid	lipid	NOUN
fnp-3528	1013	44	metabolism	metabolism	NOUN
fnp-3528	1013	45	modulators	modulator	NOUN
fnp-3528	1013	46	2	2	NUM
fnp-3528	1013	47	-	-	PUNCT
fnp-3528	1013	48	bromopalmitate	bromopalmitate	NOUN
fnp-3528	1013	49	,	,	PUNCT
fnp-3528	1013	50	d609	d609	PROPN
fnp-3528	1013	51	,	,	PUNCT
fnp-3528	1013	52	monensin	monensin	NOUN
fnp-3528	1013	53	,	,	PUNCT
fnp-3528	1013	54	u18666a	u18666a	PROPN
fnp-3528	1013	55	and	and	CCONJ
fnp-3528	1013	56	probucol	probucol	PROPN
fnp-3528	1013	57	shift	shift	NOUN
fnp-3528	1013	58	discoidal	discoidal	ADJ
fnp-3528	1013	59	hdl	hdl	NOUN
fnp-3528	1013	60	formation	formation	NOUN
fnp-3528	1013	61	to	to	ADP
fnp-3528	1013	62	the	the	DET
fnp-3528	1013	63	smaller	small	ADJ
fnp-3528	1013	64	-	-	PUNCT
fnp-3528	1013	65	sized	sized	ADJ
fnp-3528	1013	66	particles	particle	NOUN
fnp-3528	1013	67	:	:	PUNCT
fnp-3528	1013	68	implications	implication	NOUN
fnp-3528	1013	69	for	for	ADP
fnp-3528	1013	70	the	the	DET
fnp-3528	1013	71	mechanism	mechanism	NOUN
fnp-3528	1013	72	of	of	ADP
fnp-3528	1013	73	hdl	hdl	PROPN
fnp-3528	1013	74	assembly	assembly	PROPN
fnp-3528	1013	75	.	.	PUNCT
fnp-3528	1014	1	biochim	biochim	PROPN
fnp-3528	1014	2	biophys	biophy	NOUN
fnp-3528	1014	3	acta	acta	PROPN
fnp-3528	1014	4	2016	2016	NUM
fnp-3528	1014	5	,	,	PUNCT
fnp-3528	1014	6	1861	1861	NUM
fnp-3528	1014	7	,	,	PUNCT
fnp-3528	1014	8	1968	1968	NUM
fnp-3528	1014	9	-	-	SYM
fnp-3528	1014	10	79	79	NUM
fnp-3528	1014	11	.	.	PUNCT
fnp-3528	1015	1	de	de	ADP
fnp-3528	1015	2	la	la	PRON
fnp-3528	1015	3	llera	llera	PROPN
fnp-3528	1015	4	-	-	PUNCT
fnp-3528	1015	5	moya	moya	PROPN
fnp-3528	1015	6	,	,	PUNCT
fnp-3528	1015	7	m.	m.	NOUN
fnp-3528	1015	8	;	;	PUNCT
fnp-3528	1015	9	drazul	drazul	NOUN
fnp-3528	1015	10	-	-	PUNCT
fnp-3528	1015	11	schrader	schrader	NOUN
fnp-3528	1015	12	,	,	PUNCT
fnp-3528	1015	13	d.	d.	PROPN
fnp-3528	1015	14	;	;	PUNCT
fnp-3528	1015	15	asztalos	asztalos	PROPN
fnp-3528	1015	16	,	,	PUNCT
fnp-3528	1015	17	b.	b.	PROPN
fnp-3528	1015	18	f.	f.	PROPN
fnp-3528	1015	19	;	;	PUNCT
fnp-3528	1015	20	cuchel	cuchel	PROPN
fnp-3528	1015	21	,	,	PUNCT
fnp-3528	1015	22	m.	m.	NOUN
fnp-3528	1015	23	;	;	PUNCT
fnp-3528	1015	24	rader	rader	PROPN
fnp-3528	1015	25	,	,	PUNCT
fnp-3528	1015	26	d.	d.	PROPN
fnp-3528	1015	27	j.	j.	PROPN
fnp-3528	1015	28	;	;	PUNCT
fnp-3528	1015	29	rothblat	rothblat	NOUN
fnp-3528	1015	30	,	,	PUNCT
fnp-3528	1015	31	g.	g.	PROPN
fnp-3528	1015	32	h.	h.	PROPN
fnp-3528	1016	1	the	the	DET
fnp-3528	1016	2	ability	ability	NOUN
fnp-3528	1016	3	to	to	PART
fnp-3528	1016	4	promote	promote	VERB
fnp-3528	1016	5	efflux	efflux	VERB
fnp-3528	1016	6	via	via	ADP
fnp-3528	1016	7	abca1	abca1	NOUN
fnp-3528	1016	8	determines	determine	VERB
fnp-3528	1016	9	the	the	DET
fnp-3528	1016	10	capacity	capacity	NOUN
fnp-3528	1016	11	of	of	ADP
fnp-3528	1016	12	serum	serum	NOUN
fnp-3528	1016	13	specimens	specimen	NOUN
fnp-3528	1016	14	with	with	ADP
fnp-3528	1016	15	similar	similar	ADJ
fnp-3528	1016	16	high	high	ADJ
fnp-3528	1016	17	-	-	PUNCT
fnp-3528	1016	18	density	density	NOUN
fnp-3528	1016	19	lipoprotein	lipoprotein	ADJ
fnp-3528	1016	20	cholesterol	cholesterol	NOUN
fnp-3528	1016	21	to	to	PART
fnp-3528	1016	22	remove	remove	VERB
fnp-3528	1016	23	cholesterol	cholesterol	NOUN
fnp-3528	1016	24	from	from	ADP
fnp-3528	1016	25	macrophages	macrophage	NOUN
fnp-3528	1016	26	.	.	PUNCT
fnp-3528	1017	1	arterioscler	arterioscler	PROPN
fnp-3528	1017	2	thromb	thromb	PROPN
fnp-3528	1017	3	vasc	vasc	PROPN
fnp-3528	1017	4	biol	biol	PROPN
fnp-3528	1017	5	2010	2010	NUM
fnp-3528	1017	6	,	,	PUNCT
fnp-3528	1017	7	30	30	NUM
fnp-3528	1017	8	,	,	PUNCT
fnp-3528	1017	9	796	796	NUM
fnp-3528	1017	10	-	-	SYM
fnp-3528	1017	11	801	801	NUM
fnp-3528	1017	12	.	.	PUNCT
fnp-3528	1018	1	arakawa	arakawa	PROPN
fnp-3528	1018	2	,	,	PUNCT
fnp-3528	1018	3	r.	r.	PROPN
fnp-3528	1018	4	;	;	PUNCT
fnp-3528	1018	5	tsujita	tsujita	PROPN
fnp-3528	1018	6	,	,	PUNCT
fnp-3528	1018	7	m.	m.	NOUN
fnp-3528	1018	8	;	;	PUNCT
fnp-3528	1018	9	iwamoto	iwamoto	ADJ
fnp-3528	1018	10	,	,	PUNCT
fnp-3528	1018	11	n.	n.	PROPN
fnp-3528	1018	12	;	;	PUNCT
fnp-3528	1018	13	ito	ito	NOUN
fnp-3528	1018	14	-	-	NOUN
fnp-3528	1018	15	ohsumi	ohsumi	PROPN
fnp-3528	1018	16	,	,	PUNCT
fnp-3528	1018	17	c.	c.	PROPN
fnp-3528	1018	18	;	;	PUNCT
fnp-3528	1018	19	lu	lu	PROPN
fnp-3528	1018	20	,	,	PUNCT
fnp-3528	1018	21	r.	r.	PROPN
fnp-3528	1018	22	;	;	PUNCT
fnp-3528	1018	23	wu	wu	PROPN
fnp-3528	1018	24	,	,	PUNCT
fnp-3528	1018	25	c.	c.	PROPN
fnp-3528	1018	26	a.	a.	PROPN
fnp-3528	1018	27	;	;	PUNCT
fnp-3528	1018	28	shimizu	shimizu	PROPN
fnp-3528	1018	29	,	,	PUNCT
fnp-3528	1018	30	k.	k.	PROPN
fnp-3528	1018	31	;	;	PUNCT
fnp-3528	1018	32	aotsuka	aotsuka	NOUN
fnp-3528	1018	33	,	,	PUNCT
fnp-3528	1018	34	t.	t.	PROPN
fnp-3528	1018	35	;	;	PUNCT
fnp-3528	1018	36	kanazawa	kanazawa	PROPN
fnp-3528	1018	37	,	,	PUNCT
fnp-3528	1018	38	h.	h.	PROPN
fnp-3528	1018	39	;	;	PUNCT
fnp-3528	1018	40	abe	abe	PROPN
fnp-3528	1018	41	-	-	PUNCT
fnp-3528	1018	42	dohmae	dohmae	PROPN
fnp-3528	1018	43	,	,	PUNCT
fnp-3528	1018	44	s.	s.	PROPN
fnp-3528	1018	45	;	;	PUNCT
fnp-3528	1018	46	yokoyama	yokoyama	PROPN
fnp-3528	1018	47	,	,	PUNCT
fnp-3528	1018	48	s.	s.	PROPN
fnp-3528	1018	49	pharmacological	pharmacological	NOUN
fnp-3528	1018	50	inhibition	inhibition	NOUN
fnp-3528	1018	51	of	of	ADP
fnp-3528	1018	52	abca1	abca1	NOUN
fnp-3528	1018	53	degradation	degradation	NOUN
fnp-3528	1018	54	increases	increase	VERB
fnp-3528	1018	55	hdl	hdl	NOUN
fnp-3528	1018	56	biogenesis	biogenesis	NOUN
fnp-3528	1018	57	and	and	CCONJ
fnp-3528	1018	58	exhibits	exhibit	VERB
fnp-3528	1018	59	antiatherogenesis	antiatherogenesis	NOUN
fnp-3528	1018	60	.	.	PUNCT
fnp-3528	1019	1	j	j	PROPN
fnp-3528	1019	2	lipid	lipid	PROPN
fnp-3528	1019	3	res	re	NOUN
fnp-3528	1019	4	2009	2009	NUM
fnp-3528	1019	5	,	,	PUNCT
fnp-3528	1019	6	50	50	NUM
fnp-3528	1019	7	,	,	PUNCT
fnp-3528	1019	8	2299	2299	NUM
fnp-3528	1019	9	-	-	SYM
fnp-3528	1019	10	305	305	NUM
fnp-3528	1019	11	.	.	PUNCT
fnp-3528	1020	1	adorni	adorni	PROPN
fnp-3528	1020	2	,	,	PUNCT
fnp-3528	1020	3	m.	m.	NOUN
fnp-3528	1020	4	p.	p.	NOUN
fnp-3528	1020	5	;	;	PUNCT
fnp-3528	1021	1	zimetti	zimetti	PROPN
fnp-3528	1021	2	,	,	PUNCT
fnp-3528	1021	3	f.	f.	PROPN
fnp-3528	1021	4	;	;	PUNCT
fnp-3528	1021	5	billheimer	billheimer	PROPN
fnp-3528	1021	6	,	,	PUNCT
fnp-3528	1021	7	j.	j.	PROPN
fnp-3528	1021	8	t.	t.	PROPN
fnp-3528	1021	9	;	;	PUNCT
fnp-3528	1021	10	wang	wang	PROPN
fnp-3528	1021	11	,	,	PUNCT
fnp-3528	1021	12	n.	n.	PROPN
fnp-3528	1021	13	;	;	PUNCT
fnp-3528	1021	14	rader	rader	PROPN
fnp-3528	1021	15	,	,	PUNCT
fnp-3528	1021	16	d.	d.	PROPN
fnp-3528	1021	17	j.	j.	PROPN
fnp-3528	1021	18	;	;	PUNCT
fnp-3528	1021	19	phillips	phillips	PROPN
fnp-3528	1021	20	,	,	PUNCT
fnp-3528	1021	21	m.	m.	PROPN
fnp-3528	1021	22	c.	c.	PROPN
fnp-3528	1021	23	;	;	PUNCT
fnp-3528	1021	24	rothblat	rothblat	NOUN
fnp-3528	1021	25	,	,	PUNCT
fnp-3528	1021	26	g.	g.	PROPN
fnp-3528	1021	27	h.	h.	PROPN
fnp-3528	1022	1	the	the	DET
fnp-3528	1022	2	roles	role	NOUN
fnp-3528	1022	3	of	of	ADP
fnp-3528	1022	4	different	different	ADJ
fnp-3528	1022	5	pathways	pathway	NOUN
fnp-3528	1022	6	in	in	ADP
fnp-3528	1022	7	the	the	DET
fnp-3528	1022	8	release	release	NOUN
fnp-3528	1022	9	of	of	ADP
fnp-3528	1022	10	cholesterol	cholesterol	NOUN
fnp-3528	1022	11	from	from	ADP
fnp-3528	1022	12	macrophages	macrophage	NOUN
fnp-3528	1022	13	.	.	PUNCT
fnp-3528	1023	1	j	j	PROPN
fnp-3528	1023	2	lipid	lipid	PROPN
fnp-3528	1023	3	res	re	NOUN
fnp-3528	1023	4	2007	2007	NUM
fnp-3528	1023	5	,	,	PUNCT
fnp-3528	1023	6	48	48	NUM
fnp-3528	1023	7	,	,	PUNCT
fnp-3528	1023	8	2453	2453	NUM
fnp-3528	1023	9	-	-	SYM
fnp-3528	1023	10	62	62	NUM
fnp-3528	1023	11	.	.	PUNCT
fnp-3528	1024	1	duong	duong	PROPN
fnp-3528	1024	2	,	,	PUNCT
fnp-3528	1024	3	m.	m.	NOUN
fnp-3528	1024	4	;	;	PUNCT
fnp-3528	1024	5	collins	collins	PROPN
fnp-3528	1024	6	,	,	PUNCT
fnp-3528	1024	7	h.	h.	PROPN
fnp-3528	1024	8	l.	l.	PROPN
fnp-3528	1024	9	;	;	PUNCT
fnp-3528	1024	10	jin	jin	PROPN
fnp-3528	1024	11	,	,	PUNCT
fnp-3528	1024	12	w.	w.	PROPN
fnp-3528	1024	13	;	;	PUNCT
fnp-3528	1024	14	zanotti	zanotti	X
fnp-3528	1024	15	,	,	PUNCT
fnp-3528	1024	16	i.	i.	NOUN
fnp-3528	1024	17	;	;	PUNCT
fnp-3528	1024	18	favari	favari	PROPN
fnp-3528	1024	19	,	,	PUNCT
fnp-3528	1024	20	e.	e.	PROPN
fnp-3528	1024	21	;	;	PUNCT
fnp-3528	1024	22	rothblat	rothblat	NOUN
fnp-3528	1024	23	,	,	PUNCT
fnp-3528	1024	24	g.	g.	PROPN
fnp-3528	1024	25	h.	h.	PROPN
fnp-3528	1024	26	relative	relative	ADJ
fnp-3528	1024	27	contributions	contribution	NOUN
fnp-3528	1024	28	of	of	ADP
fnp-3528	1024	29	abca1	abca1	PROPN
fnp-3528	1024	30	and	and	CCONJ
fnp-3528	1024	31	sr	sr	PROPN
fnp-3528	1024	32	-	-	PUNCT
fnp-3528	1024	33	bi	bi	PROPN
fnp-3528	1024	34	to	to	ADP
fnp-3528	1024	35	cholesterol	cholesterol	NOUN
fnp-3528	1024	36	efflux	efflux	VERB
fnp-3528	1024	37	to	to	ADP
fnp-3528	1024	38	serum	serum	NOUN
fnp-3528	1024	39	from	from	ADP
fnp-3528	1024	40	fibroblasts	fibroblast	NOUN
fnp-3528	1024	41	and	and	CCONJ
fnp-3528	1024	42	macrophages	macrophage	NOUN
fnp-3528	1024	43	.	.	PUNCT
fnp-3528	1025	1	arterioscler	arterioscler	PROPN
fnp-3528	1025	2	thromb	thromb	PROPN
fnp-3528	1025	3	vasc	vasc	PROPN
fnp-3528	1025	4	biol	biol	PROPN
fnp-3528	1025	5	2006	2006	NUM
fnp-3528	1025	6	,	,	PUNCT
fnp-3528	1025	7	26	26	NUM
fnp-3528	1025	8	,	,	PUNCT
fnp-3528	1025	9	541	541	NUM
fnp-3528	1025	10	-	-	SYM
fnp-3528	1025	11	7	7	NUM
fnp-3528	1025	12	.	.	PUNCT
fnp-3528	1025	13	favari	favari	PROPN
fnp-3528	1025	14	,	,	PUNCT
fnp-3528	1025	15	e.	e.	PROPN
fnp-3528	1025	16	;	;	PUNCT
fnp-3528	1025	17	zanotti	zanotti	PROPN
fnp-3528	1025	18	,	,	PUNCT
fnp-3528	1025	19	i.	i.	NOUN
fnp-3528	1025	20	;	;	PUNCT
fnp-3528	1025	21	zimetti	zimetti	PROPN
fnp-3528	1025	22	,	,	PUNCT
fnp-3528	1025	23	f.	f.	PROPN
fnp-3528	1025	24	;	;	PUNCT
fnp-3528	1025	25	ronda	ronda	PROPN
fnp-3528	1025	26	,	,	PUNCT
fnp-3528	1025	27	n.	n.	NOUN
fnp-3528	1025	28	;	;	PUNCT
fnp-3528	1025	29	bernini	bernini	PROPN
fnp-3528	1025	30	,	,	PUNCT
fnp-3528	1025	31	f.	f.	PROPN
fnp-3528	1025	32	;	;	PUNCT
fnp-3528	1025	33	rothblat	rothblat	NOUN
fnp-3528	1025	34	,	,	PUNCT
fnp-3528	1025	35	g.	g.	PROPN
fnp-3528	1025	36	h.	h.	PROPN
fnp-3528	1025	37	probucol	probucol	PROPN
fnp-3528	1025	38	inhibits	inhibit	VERB
fnp-3528	1025	39	abca1	abca1	NOUN
fnp-3528	1025	40	-	-	PUNCT
fnp-3528	1025	41	mediated	mediate	VERB
fnp-3528	1025	42	cellular	cellular	ADJ
fnp-3528	1025	43	lipid	lipid	NOUN
fnp-3528	1025	44	efflux	efflux	NOUN
fnp-3528	1025	45	.	.	PUNCT
fnp-3528	1026	1	arterioscler	arterioscler	PROPN
fnp-3528	1026	2	thromb	thromb	PROPN
fnp-3528	1026	3	vasc	vasc	PROPN
fnp-3528	1026	4	biol	biol	PROPN
fnp-3528	1026	5	2004	2004	NUM
fnp-3528	1026	6	,	,	PUNCT
fnp-3528	1026	7	24	24	NUM
fnp-3528	1026	8	,	,	PUNCT
fnp-3528	1026	9	2345	2345	NUM
fnp-3528	1026	10	-	-	SYM
fnp-3528	1026	11	50	50	NUM
fnp-3528	1026	12	.	.	PUNCT
fnp-3528	1027	1	shinohara	shinohara	PROPN
fnp-3528	1027	2	,	,	PUNCT
fnp-3528	1027	3	m.	m.	NOUN
fnp-3528	1027	4	;	;	PUNCT
fnp-3528	1027	5	shinohara	shinohara	PROPN
fnp-3528	1027	6	,	,	PUNCT
fnp-3528	1027	7	m.	m.	NOUN
fnp-3528	1027	8	;	;	PUNCT
fnp-3528	1027	9	zhao	zhao	PROPN
fnp-3528	1027	10	,	,	PUNCT
fnp-3528	1027	11	j.	j.	PROPN
fnp-3528	1027	12	;	;	PUNCT
fnp-3528	1027	13	fu	fu	PROPN
fnp-3528	1027	14	,	,	PUNCT
fnp-3528	1027	15	y.	y.	PROPN
fnp-3528	1027	16	;	;	PUNCT
fnp-3528	1027	17	liu	liu	PROPN
fnp-3528	1027	18	,	,	PUNCT
fnp-3528	1027	19	c.	c.	PROPN
fnp-3528	1027	20	c.	c.	PROPN
fnp-3528	1027	21	;	;	PUNCT
fnp-3528	1027	22	kanekiyo	kanekiyo	PROPN
fnp-3528	1027	23	,	,	PUNCT
fnp-3528	1027	24	t.	t.	PROPN
fnp-3528	1027	25	;	;	PUNCT
fnp-3528	1027	26	bu	bu	PROPN
fnp-3528	1027	27	,	,	PUNCT
fnp-3528	1027	28	g.	g.	PROPN
fnp-3528	1027	29	5	5	NUM
fnp-3528	1027	30	-	-	PUNCT
fnp-3528	1027	31	ht3	ht3	NOUN
fnp-3528	1027	32	antagonist	antagonist	NOUN
fnp-3528	1027	33	ondansetron	ondansetron	NOUN
fnp-3528	1027	34	increases	increase	NOUN
fnp-3528	1027	35	apoe	apoe	ADP
fnp-3528	1027	36	secretion	secretion	NOUN
fnp-3528	1027	37	by	by	ADP
fnp-3528	1027	38	modulating	modulate	VERB
fnp-3528	1027	39	the	the	DET
fnp-3528	1027	40	lxr	lxr	NOUN
fnp-3528	1027	41	-	-	PUNCT
fnp-3528	1027	42	abca1	abca1	NOUN
fnp-3528	1027	43	pathway	pathway	NOUN
fnp-3528	1027	44	.	.	PUNCT
fnp-3528	1028	1	int	int	PROPN
fnp-3528	1028	2	j	j	PROPN
fnp-3528	1028	3	mol	mol	ADP
fnp-3528	1028	4	sci	sci	PROPN
fnp-3528	1028	5	2019	2019	NUM
fnp-3528	1028	6	,	,	PUNCT
fnp-3528	1028	7	20	20	NUM
fnp-3528	1028	8	.	.	PUNCT
fnp-3528	1029	1	wang	wang	PROPN
fnp-3528	1029	2	,	,	PUNCT
fnp-3528	1029	3	w.	w.	PROPN
fnp-3528	1029	4	;	;	PUNCT
fnp-3528	1029	5	nakashima	nakashima	PROPN
fnp-3528	1029	6	,	,	PUNCT
fnp-3528	1029	7	k.	k.	PROPN
fnp-3528	1029	8	i.	i.	PROPN
fnp-3528	1029	9	;	;	PUNCT
fnp-3528	1029	10	hirai	hirai	NOUN
fnp-3528	1029	11	,	,	PUNCT
fnp-3528	1029	12	t.	t.	PROPN
fnp-3528	1029	13	;	;	PUNCT
fnp-3528	1029	14	inoue	inoue	PROPN
fnp-3528	1029	15	,	,	PUNCT
fnp-3528	1029	16	m.	m.	NOUN
fnp-3528	1029	17	neuroprotective	neuroprotective	ADJ
fnp-3528	1029	18	effect	effect	NOUN
fnp-3528	1029	19	of	of	ADP
fnp-3528	1029	20	naturally	naturally	ADV
fnp-3528	1029	21	occurring	occur	VERB
fnp-3528	1029	22	rxr	rxr	PROPN
fnp-3528	1029	23	agonists	agonist	NOUN
fnp-3528	1029	24	isolated	isolate	VERB
fnp-3528	1029	25	from	from	ADP
fnp-3528	1029	26	sophora	sophora	PROPN
fnp-3528	1029	27	tonkinensis	tonkinensis	NUM
fnp-3528	1029	28	gagnep	gagnep	NOUN
fnp-3528	1029	29	.	.	PUNCT
fnp-3528	1030	1	on	on	ADP
fnp-3528	1030	2	amyloid	amyloid	NOUN
fnp-3528	1030	3	-	-	PUNCT
fnp-3528	1030	4	beta	beta	NOUN
fnp-3528	1030	5	-	-	PUNCT
fnp-3528	1030	6	induced	induce	VERB
fnp-3528	1030	7	cytotoxicity	cytotoxicity	NOUN
fnp-3528	1030	8	in	in	ADP
fnp-3528	1030	9	pc12	pc12	PROPN
fnp-3528	1030	10	cells	cell	NOUN
fnp-3528	1030	11	.	.	PUNCT
fnp-3528	1031	1	j	j	PROPN
fnp-3528	1031	2	nat	nat	PROPN
fnp-3528	1031	3	med	me	VERB
fnp-3528	1031	4	2019	2019	NUM
fnp-3528	1031	5	,	,	PUNCT
fnp-3528	1031	6	73	73	NUM
fnp-3528	1031	7	,	,	PUNCT
fnp-3528	1031	8	154	154	NUM
fnp-3528	1031	9	-	-	SYM
fnp-3528	1031	10	62	62	NUM
fnp-3528	1031	11	.	.	PUNCT
fnp-3528	1032	1	kheirollah	kheirollah	PROPN
fnp-3528	1032	2	,	,	PUNCT
fnp-3528	1032	3	a.	a.	PROPN
fnp-3528	1032	4	;	;	PUNCT
fnp-3528	1032	5	ito	ito	PROPN
fnp-3528	1032	6	,	,	PUNCT
fnp-3528	1032	7	j.	j.	PROPN
fnp-3528	1032	8	;	;	PUNCT
fnp-3528	1032	9	nagayasu	nagayasu	VERB
fnp-3528	1032	10	,	,	PUNCT
fnp-3528	1032	11	y.	y.	PROPN
fnp-3528	1032	12	;	;	PUNCT
fnp-3528	1032	13	lu	lu	PROPN
fnp-3528	1032	14	,	,	PUNCT
fnp-3528	1032	15	r.	r.	PROPN
fnp-3528	1032	16	;	;	PUNCT
fnp-3528	1032	17	yokoyama	yokoyama	PROPN
fnp-3528	1032	18	,	,	PUNCT
fnp-3528	1032	19	s.	s.	PROPN
fnp-3528	1032	20	cyclosporin	cyclosporin	PROPN
fnp-3528	1032	21	a	a	DET
fnp-3528	1032	22	inhibits	inhibit	NOUN
fnp-3528	1032	23	apolipoprotein	apolipoprotein	ADJ
fnp-3528	1032	24	a	a	PRON
fnp-3528	1032	25	-	-	PUNCT
fnp-3528	1032	26	i	i	PRON
fnp-3528	1032	27	-	-	PUNCT
fnp-3528	1032	28	induced	induce	VERB
fnp-3528	1032	29	early	early	ADJ
fnp-3528	1032	30	events	event	NOUN
fnp-3528	1032	31	in	in	ADP
fnp-3528	1032	32	cellular	cellular	ADJ
fnp-3528	1032	33	cholesterol	cholesterol	NOUN
fnp-3528	1032	34	homeostasis	homeostasis	NOUN
fnp-3528	1032	35	in	in	ADP
fnp-3528	1032	36	rat	rat	NOUN
fnp-3528	1032	37	astrocytes	astrocyte	NOUN
fnp-3528	1032	38	.	.	PUNCT
fnp-3528	1033	1	neuropharmacol	neuropharmacol	PROPN
fnp-3528	1033	2	2006	2006	NUM
fnp-3528	1033	3	,	,	PUNCT
fnp-3528	1033	4	51	51	NUM
fnp-3528	1033	5	,	,	PUNCT
fnp-3528	1033	6	693	693	NUM
fnp-3528	1033	7	-	-	SYM
fnp-3528	1033	8	700	700	NUM
fnp-3528	1033	9	.	.	PUNCT
fnp-3528	1034	1	palmer	palmer	NOUN
fnp-3528	1034	2	,	,	PUNCT
fnp-3528	1034	3	m.	m.	NOUN
fnp-3528	1034	4	a.	a.	NOUN
fnp-3528	1034	5	;	;	PUNCT
fnp-3528	1034	6	smart	smart	ADJ
fnp-3528	1034	7	,	,	PUNCT
fnp-3528	1034	8	e.	e.	PROPN
fnp-3528	1034	9	;	;	PUNCT
fnp-3528	1034	10	haslam	haslam	PROPN
fnp-3528	1034	11	,	,	PUNCT
fnp-3528	1034	12	i.	i.	PROPN
fnp-3528	1034	13	s.	s.	PROPN
fnp-3528	1034	14	localisation	localisation	PROPN
fnp-3528	1034	15	and	and	CCONJ
fnp-3528	1034	16	regulation	regulation	NOUN
fnp-3528	1034	17	of	of	ADP
fnp-3528	1034	18	cholesterol	cholesterol	NOUN
fnp-3528	1034	19	transporters	transporter	NOUN
fnp-3528	1034	20	in	in	ADP
fnp-3528	1034	21	the	the	DET
fnp-3528	1034	22	human	human	ADJ
fnp-3528	1034	23	hair	hair	NOUN
fnp-3528	1034	24	follicle	follicle	NOUN
fnp-3528	1034	25	:	:	PUNCT
fnp-3528	1034	26	mapping	mapping	NOUN
fnp-3528	1034	27	changes	change	NOUN
fnp-3528	1034	28	across	across	ADP
fnp-3528	1034	29	the	the	DET
fnp-3528	1034	30	hair	hair	NOUN
fnp-3528	1034	31	cycle	cycle	NOUN
fnp-3528	1034	32	.	.	PUNCT
fnp-3528	1035	1	histochem	histochem	PROPN
fnp-3528	1035	2	cell	cell	NOUN
fnp-3528	1035	3	biol	biol	PROPN
fnp-3528	1035	4	2021	2021	NUM
fnp-3528	1035	5	,	,	PUNCT
fnp-3528	1035	6	155	155	NUM
fnp-3528	1035	7	,	,	PUNCT
fnp-3528	1035	8	529	529	NUM
fnp-3528	1035	9	-	-	SYM
fnp-3528	1035	10	45	45	NUM
fnp-3528	1035	11	.	.	PUNCT
fnp-3528	1036	1	bardin	bardin	NOUN
fnp-3528	1036	2	,	,	PUNCT
fnp-3528	1036	3	e.	e.	PROPN
fnp-3528	1036	4	;	;	PUNCT
fnp-3528	1036	5	pastor	pastor	PROPN
fnp-3528	1036	6	,	,	PUNCT
fnp-3528	1036	7	a.	a.	NOUN
fnp-3528	1036	8	;	;	PUNCT
fnp-3528	1036	9	semeraro	semeraro	NOUN
fnp-3528	1036	10	,	,	PUNCT
fnp-3528	1036	11	m.	m.	NOUN
fnp-3528	1036	12	;	;	PUNCT
fnp-3528	1036	13	golec	golec	NOUN
fnp-3528	1036	14	,	,	PUNCT
fnp-3528	1036	15	a.	a.	NOUN
fnp-3528	1036	16	;	;	PUNCT
fnp-3528	1036	17	hayes	hayes	PROPN
fnp-3528	1036	18	,	,	PUNCT
fnp-3528	1036	19	k.	k.	PROPN
fnp-3528	1036	20	;	;	PUNCT
fnp-3528	1036	21	chevalier	chevalier	NOUN
fnp-3528	1036	22	,	,	PUNCT
fnp-3528	1036	23	b.	b.	PROPN
fnp-3528	1036	24	;	;	PUNCT
fnp-3528	1036	25	berhal	berhal	PROPN
fnp-3528	1036	26	,	,	PUNCT
fnp-3528	1036	27	f.	f.	PROPN
fnp-3528	1036	28	;	;	PUNCT
fnp-3528	1036	29	prestat	prestat	PROPN
fnp-3528	1036	30	,	,	PUNCT
fnp-3528	1036	31	g.	g.	PROPN
fnp-3528	1036	32	;	;	PUNCT
fnp-3528	1036	33	hinzpeter	hinzpeter	PROPN
fnp-3528	1036	34	,	,	PUNCT
fnp-3528	1036	35	a.	a.	NOUN
fnp-3528	1036	36	;	;	PUNCT
fnp-3528	1036	37	gravier	gravier	NOUN
fnp-3528	1036	38	-	-	PUNCT
fnp-3528	1036	39	pelletier	pelletier	PROPN
fnp-3528	1036	40	,	,	PUNCT
fnp-3528	1036	41	c.	c.	PROPN
fnp-3528	1036	42	;	;	PUNCT
fnp-3528	1036	43	pranke	pranke	NOUN
fnp-3528	1036	44	,	,	PUNCT
fnp-3528	1036	45	i.	i.	NOUN
fnp-3528	1036	46	;	;	PUNCT
fnp-3528	1036	47	sermet	sermet	NOUN
fnp-3528	1036	48	-	-	PUNCT
fnp-3528	1036	49	gaudelus	gaudelus	NOUN
fnp-3528	1036	50	,	,	PUNCT
fnp-3528	1036	51	i.	i.	NOUN
fnp-3528	1036	52	modulators	modulator	NOUN
fnp-3528	1036	53	of	of	ADP
fnp-3528	1036	54	cftr	cftr	NOUN
fnp-3528	1036	55	.	.	PUNCT
fnp-3528	1037	1	updates	update	NOUN
fnp-3528	1037	2	on	on	ADP
fnp-3528	1037	3	clinical	clinical	ADJ
fnp-3528	1037	4	development	development	NOUN
fnp-3528	1037	5	and	and	CCONJ
fnp-3528	1037	6	future	future	ADJ
fnp-3528	1037	7	directions	direction	NOUN
fnp-3528	1037	8	.	.	PUNCT
fnp-3528	1038	1	eur	eur	PROPN
fnp-3528	1038	2	j	j	PROPN
fnp-3528	1038	3	med	me	VERB
fnp-3528	1038	4	chem	chem	NOUN
fnp-3528	1038	5	2021	2021	NUM
fnp-3528	1038	6	,	,	PUNCT
fnp-3528	1038	7	213	213	NUM
fnp-3528	1038	8	,	,	PUNCT
fnp-3528	1038	9	113195	113195	NUM
fnp-3528	1038	10	.	.	PUNCT
fnp-3528	1038	11	schmitt	schmitt	NOUN
fnp-3528	1038	12	,	,	PUNCT
fnp-3528	1038	13	s.	s.	PROPN
fnp-3528	1038	14	m.	m.	PROPN
fnp-3528	1038	15	;	;	PUNCT
fnp-3528	1038	16	stefan	stefan	PROPN
fnp-3528	1038	17	,	,	PUNCT
fnp-3528	1038	18	k.	k.	PROPN
fnp-3528	1038	19	;	;	PUNCT
fnp-3528	1038	20	wiese	wiese	PROPN
fnp-3528	1038	21	,	,	PUNCT
fnp-3528	1038	22	m.	m.	NOUN
fnp-3528	1038	23	pyrrolopyrimidine	pyrrolopyrimidine	NOUN
fnp-3528	1038	24	derivatives	derivative	NOUN
fnp-3528	1038	25	and	and	CCONJ
fnp-3528	1038	26	purine	purine	NOUN
fnp-3528	1038	27	analogs	analog	NOUN
fnp-3528	1038	28	as	as	ADP
fnp-3528	1038	29	novel	novel	ADJ
fnp-3528	1038	30	activators	activator	NOUN
fnp-3528	1038	31	of	of	ADP
fnp-3528	1038	32	multidrug	multidrug	NOUN
fnp-3528	1038	33	resistance	resistance	NOUN
fnp-3528	1038	34	-	-	PUNCT
fnp-3528	1038	35	associated	associate	VERB
fnp-3528	1038	36	protein	protein	NOUN
fnp-3528	1038	37	1	1	NUM
fnp-3528	1038	38	(	(	PUNCT
fnp-3528	1038	39	mrp1	mrp1	NOUN
fnp-3528	1038	40	,	,	PUNCT
fnp-3528	1038	41	abcc1	abcc1	PROPN
fnp-3528	1038	42	)	)	PUNCT
fnp-3528	1038	43	.	.	PUNCT
fnp-3528	1039	1	biochim	biochim	PROPN
fnp-3528	1039	2	biophys	biophy	NOUN
fnp-3528	1039	3	acta	acta	PROPN
fnp-3528	1039	4	2017	2017	NUM
fnp-3528	1039	5	,	,	PUNCT
fnp-3528	1039	6	1859	1859	NUM
fnp-3528	1039	7	,	,	PUNCT
fnp-3528	1039	8	69	69	NUM
fnp-3528	1039	9	-	-	SYM
fnp-3528	1039	10	79	79	NUM
fnp-3528	1039	11	.	.	PUNCT
fnp-3528	1040	1	trechot	trechot	VERB
fnp-3528	1040	2	,	,	PUNCT
fnp-3528	1040	3	p.	p.	NOUN
fnp-3528	1040	4	;	;	PUNCT
fnp-3528	1040	5	conart	conart	PROPN
fnp-3528	1040	6	,	,	PUNCT
fnp-3528	1040	7	j.	j.	PROPN
fnp-3528	1040	8	b.	b.	PROPN
fnp-3528	1040	9	;	;	PUNCT
fnp-3528	1040	10	trechot	trechot	VERB
fnp-3528	1040	11	,	,	PUNCT
fnp-3528	1040	12	f.	f.	PROPN
fnp-3528	1040	13	atp	atp	PROPN
fnp-3528	1040	14	sensitive	sensitive	ADJ
fnp-3528	1040	15	potassium	potassium	NOUN
fnp-3528	1040	16	channel	channel	NOUN
fnp-3528	1040	17	openers	opener	NOUN
fnp-3528	1040	18	:	:	PUNCT
fnp-3528	1040	19	a	a	DET
fnp-3528	1040	20	new	new	ADJ
fnp-3528	1040	21	class	class	NOUN
fnp-3528	1040	22	of	of	ADP
fnp-3528	1040	23	ocular	ocular	ADJ
fnp-3528	1040	24	hypotensive	hypotensive	ADJ
fnp-3528	1040	25	agents	agent	NOUN
fnp-3528	1040	26	.	.	PUNCT
fnp-3528	1041	1	exp	exp	NOUN
fnp-3528	1041	2	eye	eye	NOUN
fnp-3528	1041	3	res	re	NOUN
fnp-3528	1041	4	2019	2019	NUM
fnp-3528	1041	5	,	,	PUNCT
fnp-3528	1041	6	178	178	NUM
fnp-3528	1041	7	,	,	PUNCT
fnp-3528	1041	8	223	223	NUM
fnp-3528	1041	9	-	-	SYM
fnp-3528	1041	10	4	4	NUM
fnp-3528	1041	11	.	.	PUNCT
fnp-3528	1042	1	csandl	csandl	NOUN
fnp-3528	1042	2	,	,	PUNCT
fnp-3528	1042	3	m.	m.	NOUN
fnp-3528	1042	4	a.	a.	PROPN
fnp-3528	1042	5	;	;	PUNCT
fnp-3528	1042	6	conseil	conseil	PROPN
fnp-3528	1042	7	,	,	PUNCT
fnp-3528	1042	8	g.	g.	PROPN
fnp-3528	1042	9	;	;	PUNCT
fnp-3528	1042	10	cole	cole	PROPN
fnp-3528	1042	11	,	,	PUNCT
fnp-3528	1042	12	s.	s.	PROPN
fnp-3528	1042	13	p.	p.	PROPN
fnp-3528	1042	14	cysteinyl	cysteinyl	PROPN
fnp-3528	1042	15	leukotriene	leukotriene	PROPN
fnp-3528	1042	16	receptor	receptor	NOUN
fnp-3528	1042	17	1/2	1/2	NUM
fnp-3528	1042	18	antagonists	antagonist	NOUN
fnp-3528	1042	19	nonselectively	nonselectively	ADV
fnp-3528	1042	20	modulate	modulate	VERB
fnp-3528	1042	21	organic	organic	ADJ
fnp-3528	1042	22	anion	anion	NOUN
fnp-3528	1042	23	transport	transport	NOUN
fnp-3528	1042	24	by	by	ADP
fnp-3528	1042	25	multidrug	multidrug	NOUN
fnp-3528	1042	26	resistance	resistance	NOUN
fnp-3528	1042	27	proteins	protein	NOUN
fnp-3528	1042	28	(	(	PUNCT
fnp-3528	1042	29	mrp1	mrp1	NOUN
fnp-3528	1042	30	-	-	PUNCT
fnp-3528	1042	31	4	4	NUM
fnp-3528	1042	32	)	)	PUNCT
fnp-3528	1042	33	.	.	PUNCT
fnp-3528	1043	1	drug	drug	NOUN
fnp-3528	1043	2	metab	metab	PROPN
fnp-3528	1043	3	dispos	dispos	PROPN
fnp-3528	1043	4	2016	2016	NUM
fnp-3528	1043	5	,	,	PUNCT
fnp-3528	1043	6	44	44	NUM
fnp-3528	1043	7	,	,	PUNCT
fnp-3528	1043	8	857	857	NUM
fnp-3528	1043	9	-	-	SYM
fnp-3528	1043	10	66	66	NUM
fnp-3528	1043	11	.	.	PUNCT
fnp-3528	1044	1	wang	wang	PROPN
fnp-3528	1044	2	,	,	PUNCT
fnp-3528	1044	3	h.	h.	PROPN
fnp-3528	1044	4	;	;	PUNCT
fnp-3528	1044	5	tang	tang	PROPN
fnp-3528	1044	6	,	,	PUNCT
fnp-3528	1044	7	y.	y.	PROPN
fnp-3528	1044	8	;	;	PUNCT
fnp-3528	1044	9	wang	wang	PROPN
fnp-3528	1044	10	,	,	PUNCT
fnp-3528	1044	11	l.	l.	PROPN
fnp-3528	1044	12	;	;	PUNCT
fnp-3528	1044	13	long	long	ADV
fnp-3528	1044	14	,	,	PUNCT
fnp-3528	1044	15	c.	c.	PROPN
fnp-3528	1044	16	l.	l.	PROPN
fnp-3528	1044	17	;	;	PUNCT
fnp-3528	1044	18	zhang	zhang	PROPN
fnp-3528	1044	19	,	,	PUNCT
fnp-3528	1044	20	y.	y.	PROPN
fnp-3528	1044	21	l.	l.	PROPN
fnp-3528	1044	22	atp	atp	PROPN
fnp-3528	1044	23	-	-	PUNCT
fnp-3528	1044	24	sensitive	sensitive	ADJ
fnp-3528	1044	25	potassium	potassium	NOUN
fnp-3528	1044	26	channel	channel	NOUN
fnp-3528	1044	27	openers	opener	NOUN
fnp-3528	1044	28	and	and	CCONJ
fnp-3528	1044	29	2,3	2,3	NUM
fnp-3528	1044	30	-	-	PUNCT
fnp-3528	1044	31	dimethyl-2	dimethyl-2	NUM
fnp-3528	1044	32	-	-	PUNCT
fnp-3528	1044	33	butylamine	butylamine	NOUN
fnp-3528	1044	34	derivatives	derivative	NOUN
fnp-3528	1044	35	.	.	PUNCT
fnp-3528	1045	1	curr	curr	PROPN
fnp-3528	1045	2	med	med	PROPN
fnp-3528	1045	3	chem	chem	NOUN
fnp-3528	1045	4	2007	2007	NUM
fnp-3528	1045	5	,	,	PUNCT
fnp-3528	1045	6	14	14	NUM
fnp-3528	1045	7	,	,	PUNCT
fnp-3528	1045	8	133	133	NUM
fnp-3528	1045	9	-	-	SYM
fnp-3528	1045	10	55	55	NUM
fnp-3528	1045	11	.	.	PUNCT
fnp-3528	1046	1	moreau	moreau	PROPN
fnp-3528	1046	2	,	,	PUNCT
fnp-3528	1046	3	c.	c.	PROPN
fnp-3528	1046	4	;	;	PUNCT
fnp-3528	1046	5	prost	prost	PROPN
fnp-3528	1046	6	,	,	PUNCT
fnp-3528	1046	7	a.	a.	PROPN
fnp-3528	1046	8	l.	l.	PROPN
fnp-3528	1046	9	;	;	PUNCT
fnp-3528	1046	10	derand	derand	PROPN
fnp-3528	1046	11	,	,	PUNCT
fnp-3528	1046	12	r.	r.	PROPN
fnp-3528	1046	13	;	;	PUNCT
fnp-3528	1046	14	vivaudou	vivaudou	NOUN
fnp-3528	1046	15	,	,	PUNCT
fnp-3528	1046	16	m.	m.	NOUN
fnp-3528	1046	17	sur	sur	PROPN
fnp-3528	1046	18	,	,	PUNCT
fnp-3528	1046	19	abc	abc	PROPN
fnp-3528	1046	20	proteins	protein	NOUN
fnp-3528	1046	21	targeted	target	VERB
fnp-3528	1046	22	by	by	ADP
fnp-3528	1046	23	katp	katp	NOUN
fnp-3528	1046	24	channel	channel	NOUN
fnp-3528	1046	25	openers	opener	NOUN
fnp-3528	1046	26	.	.	PUNCT
fnp-3528	1047	1	j	j	PROPN
fnp-3528	1047	2	mol	mol	PROPN
fnp-3528	1047	3	cell	cell	NOUN
fnp-3528	1047	4	cardiol	cardiol	NOUN
fnp-3528	1047	5	2005	2005	NUM
fnp-3528	1047	6	,	,	PUNCT
fnp-3528	1047	7	38	38	NUM
fnp-3528	1047	8	,	,	PUNCT
fnp-3528	1047	9	951	951	NUM
fnp-3528	1047	10	-	-	SYM
fnp-3528	1047	11	63	63	NUM
fnp-3528	1047	12	.	.	PUNCT
fnp-3528	1048	1	bielicki	bielicki	PROPN
fnp-3528	1048	2	,	,	PUNCT
fnp-3528	1048	3	j.	j.	PROPN
fnp-3528	1048	4	k.	k.	PROPN
fnp-3528	1048	5	;	;	PUNCT
fnp-3528	1048	6	zhang	zhang	PROPN
fnp-3528	1048	7	,	,	PUNCT
fnp-3528	1048	8	h.	h.	PROPN
fnp-3528	1048	9	;	;	PUNCT
fnp-3528	1048	10	cortez	cortez	PROPN
fnp-3528	1048	11	,	,	PUNCT
fnp-3528	1048	12	y.	y.	PROPN
fnp-3528	1048	13	;	;	PUNCT
fnp-3528	1048	14	zheng	zheng	PROPN
fnp-3528	1048	15	,	,	PUNCT
fnp-3528	1048	16	y.	y.	PROPN
fnp-3528	1048	17	;	;	PUNCT
fnp-3528	1048	18	narayanaswami	narayanaswami	PROPN
fnp-3528	1048	19	,	,	PUNCT
fnp-3528	1048	20	v.	v.	PROPN
fnp-3528	1048	21	;	;	PUNCT
fnp-3528	1048	22	patel	patel	PROPN
fnp-3528	1048	23	,	,	PUNCT
fnp-3528	1048	24	a.	a.	NOUN
fnp-3528	1048	25	;	;	PUNCT
fnp-3528	1048	26	johansson	johansson	PROPN
fnp-3528	1048	27	,	,	PUNCT
fnp-3528	1048	28	j.	j.	PROPN
fnp-3528	1048	29	;	;	PUNCT
fnp-3528	1048	30	azhar	azhar	PROPN
fnp-3528	1048	31	,	,	PUNCT
fnp-3528	1048	32	s.	s.	PROPN
fnp-3528	1048	33	a	a	DET
fnp-3528	1048	34	new	new	ADJ
fnp-3528	1048	35	hdl	hdl	PROPN
fnp-3528	1048	36	mimetic	mimetic	ADJ
fnp-3528	1048	37	peptide	peptide	NOUN
fnp-3528	1048	38	that	that	PRON
fnp-3528	1048	39	stimulates	stimulate	VERB
fnp-3528	1048	40	cellular	cellular	ADJ
fnp-3528	1048	41	cholesterol	cholesterol	NOUN
fnp-3528	1048	42	efflux	efflux	VERB
fnp-3528	1048	43	with	with	ADP
fnp-3528	1048	44	high	high	ADJ
fnp-3528	1048	45	efficiency	efficiency	NOUN
fnp-3528	1048	46	greatly	greatly	ADV
fnp-3528	1048	47	reduces	reduce	VERB
fnp-3528	1048	48	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1048	49	in	in	ADP
fnp-3528	1048	50	mice	mouse	NOUN
fnp-3528	1048	51	.	.	PUNCT
fnp-3528	1049	1	j	j	PROPN
fnp-3528	1049	2	lipid	lipid	PROPN
fnp-3528	1049	3	res	re	NOUN
fnp-3528	1049	4	2010	2010	NUM
fnp-3528	1049	5	,	,	PUNCT
fnp-3528	1049	6	51	51	NUM
fnp-3528	1049	7	,	,	PUNCT
fnp-3528	1049	8	1496	1496	NUM
fnp-3528	1049	9	-	-	SYM
fnp-3528	1049	10	503	503	NUM
fnp-3528	1049	11	.	.	PUNCT
fnp-3528	1050	1	natarajan	natarajan	PROPN
fnp-3528	1050	2	,	,	PUNCT
fnp-3528	1050	3	p.	p.	PROPN
fnp-3528	1050	4	;	;	PUNCT
fnp-3528	1050	5	forte	forte	NOUN
fnp-3528	1050	6	,	,	PUNCT
fnp-3528	1050	7	t.	t.	NOUN
fnp-3528	1050	8	m.	m.	NOUN
fnp-3528	1050	9	;	;	PUNCT
fnp-3528	1050	10	chu	chu	PROPN
fnp-3528	1050	11	,	,	PUNCT
fnp-3528	1050	12	b.	b.	PROPN
fnp-3528	1050	13	;	;	PUNCT
fnp-3528	1050	14	phillips	phillips	PROPN
fnp-3528	1050	15	,	,	PUNCT
fnp-3528	1050	16	m.	m.	PROPN
fnp-3528	1050	17	c.	c.	PROPN
fnp-3528	1050	18	;	;	PUNCT
fnp-3528	1050	19	oram	oram	PROPN
fnp-3528	1050	20	,	,	PUNCT
fnp-3528	1050	21	j.	j.	PROPN
fnp-3528	1050	22	f.	f.	PROPN
fnp-3528	1050	23	;	;	PUNCT
fnp-3528	1050	24	bielicki	bielicki	PROPN
fnp-3528	1050	25	,	,	PUNCT
fnp-3528	1050	26	j.	j.	PROPN
fnp-3528	1050	27	k.	k.	PROPN
fnp-3528	1050	28	identification	identification	NOUN
fnp-3528	1050	29	of	of	ADP
fnp-3528	1050	30	an	an	DET
fnp-3528	1050	31	apolipoprotein	apolipoprotein	ADJ
fnp-3528	1050	32	a	a	PRON
fnp-3528	1050	33	-	-	PUNCT
fnp-3528	1050	34	i	i	PRON
fnp-3528	1050	35	structural	structural	ADJ
fnp-3528	1050	36	element	element	NOUN
fnp-3528	1050	37	that	that	PRON
fnp-3528	1050	38	mediates	mediate	VERB
fnp-3528	1050	39	cellular	cellular	ADJ
fnp-3528	1050	40	cholesterol	cholesterol	NOUN
fnp-3528	1050	41	efflux	efflux	NOUN
fnp-3528	1050	42	and	and	CCONJ
fnp-3528	1050	43	stabilizes	stabilize	VERB
fnp-3528	1050	44	atp	atp	NOUN
fnp-3528	1050	45	binding	bind	VERB
fnp-3528	1050	46	cassette	cassette	NOUN
fnp-3528	1050	47	transporter	transporter	NOUN
fnp-3528	1050	48	a1	a1	NOUN
fnp-3528	1050	49	.	.	PUNCT
fnp-3528	1051	1	j	j	PROPN
fnp-3528	1051	2	biol	biol	PROPN
fnp-3528	1051	3	chem	chem	NOUN
fnp-3528	1051	4	2004	2004	NUM
fnp-3528	1051	5	,	,	PUNCT
fnp-3528	1051	6	279	279	NUM
fnp-3528	1051	7	,	,	PUNCT
fnp-3528	1051	8	24044	24044	NUM
fnp-3528	1051	9	-	-	SYM
fnp-3528	1051	10	52	52	NUM
fnp-3528	1051	11	.	.	PUNCT
fnp-3528	1052	1	vedhachalam	vedhachalam	PROPN
fnp-3528	1052	2	,	,	PUNCT
fnp-3528	1052	3	c.	c.	PROPN
fnp-3528	1052	4	;	;	PUNCT
fnp-3528	1052	5	narayanaswami	narayanaswami	PROPN
fnp-3528	1052	6	,	,	PUNCT
fnp-3528	1052	7	v.	v.	PROPN
fnp-3528	1052	8	;	;	PUNCT
fnp-3528	1052	9	neto	neto	VERB
fnp-3528	1052	10	,	,	PUNCT
fnp-3528	1052	11	n.	n.	NOUN
fnp-3528	1052	12	;	;	PUNCT
fnp-3528	1052	13	forte	forte	NOUN
fnp-3528	1052	14	,	,	PUNCT
fnp-3528	1052	15	t.	t.	NOUN
fnp-3528	1052	16	m.	m.	NOUN
fnp-3528	1052	17	;	;	PUNCT
fnp-3528	1052	18	phillips	phillips	PROPN
fnp-3528	1052	19	,	,	PUNCT
fnp-3528	1052	20	m.	m.	PROPN
fnp-3528	1052	21	c.	c.	PROPN
fnp-3528	1052	22	;	;	PUNCT
fnp-3528	1052	23	lund	lund	PROPN
fnp-3528	1052	24	-	-	PUNCT
fnp-3528	1052	25	katz	katz	PROPN
fnp-3528	1052	26	,	,	PUNCT
fnp-3528	1052	27	s.	s.	PROPN
fnp-3528	1052	28	;	;	PUNCT
fnp-3528	1052	29	bielicki	bielicki	PROPN
fnp-3528	1052	30	,	,	PUNCT
fnp-3528	1052	31	j.	j.	PROPN
fnp-3528	1052	32	k.	k.	PROPN
fnp-3528	1053	1	the	the	DET
fnp-3528	1053	2	c	c	NOUN
fnp-3528	1053	3	-	-	PUNCT
fnp-3528	1053	4	terminal	terminal	ADJ
fnp-3528	1053	5	lipid	lipid	NOUN
fnp-3528	1053	6	-	-	PUNCT
fnp-3528	1053	7	binding	bind	VERB
fnp-3528	1053	8	domain	domain	NOUN
fnp-3528	1053	9	of	of	ADP
fnp-3528	1053	10	apolipoprotein	apolipoprotein	ADJ
fnp-3528	1053	11	e	e	PROPN
fnp-3528	1053	12	is	be	AUX
fnp-3528	1053	13	a	a	DET
fnp-3528	1053	14	highly	highly	ADV
fnp-3528	1053	15	efficient	efficient	ADJ
fnp-3528	1053	16	mediator	mediator	NOUN
fnp-3528	1053	17	of	of	ADP
fnp-3528	1053	18	abca1	abca1	NOUN
fnp-3528	1053	19	-	-	PUNCT
fnp-3528	1053	20	dependent	dependent	ADJ
fnp-3528	1053	21	cholesterol	cholesterol	NOUN
fnp-3528	1053	22	efflux	efflux	NOUN
fnp-3528	1053	23	that	that	PRON
fnp-3528	1053	24	promotes	promote	VERB
fnp-3528	1053	25	the	the	DET
fnp-3528	1053	26	assembly	assembly	NOUN
fnp-3528	1053	27	of	of	ADP
fnp-3528	1053	28	high	high	ADJ
fnp-3528	1053	29	-	-	PUNCT
fnp-3528	1053	30	density	density	NOUN
fnp-3528	1053	31	lipoproteins	lipoprotein	NOUN
fnp-3528	1053	32	.	.	PUNCT
fnp-3528	1054	1	biochemistry	biochemistry	NOUN
fnp-3528	1054	2	2007	2007	NUM
fnp-3528	1054	3	,	,	PUNCT
fnp-3528	1054	4	46	46	NUM
fnp-3528	1054	5	,	,	PUNCT
fnp-3528	1054	6	2583	2583	NUM
fnp-3528	1054	7	-	-	SYM
fnp-3528	1054	8	93	93	NUM
fnp-3528	1054	9	.	.	PUNCT
fnp-3528	1055	1	hafiane	hafiane	PROPN
fnp-3528	1055	2	,	,	PUNCT
fnp-3528	1055	3	a.	a.	NOUN
fnp-3528	1055	4	;	;	PUNCT
fnp-3528	1055	5	bielicki	bielicki	PROPN
fnp-3528	1055	6	,	,	PUNCT
fnp-3528	1055	7	j.	j.	PROPN
fnp-3528	1055	8	k.	k.	PROPN
fnp-3528	1055	9	;	;	PUNCT
fnp-3528	1055	10	johansson	johansson	PROPN
fnp-3528	1055	11	,	,	PUNCT
fnp-3528	1055	12	j.	j.	PROPN
fnp-3528	1055	13	o.	o.	PROPN
fnp-3528	1055	14	;	;	PUNCT
fnp-3528	1055	15	genest	genest	PROPN
fnp-3528	1055	16	,	,	PUNCT
fnp-3528	1055	17	j.	j.	PROPN
fnp-3528	1055	18	novel	novel	PROPN
fnp-3528	1055	19	apoe	apoe	ADJ
fnp-3528	1055	20	-	-	PUNCT
fnp-3528	1055	21	derived	derive	VERB
fnp-3528	1055	22	abca1	abca1	NOUN
fnp-3528	1055	23	agonist	agonist	NOUN
fnp-3528	1055	24	peptide	peptide	NOUN
fnp-3528	1055	25	(	(	PUNCT
fnp-3528	1055	26	cs-6253	cs-6253	ADJ
fnp-3528	1055	27	)	)	PUNCT
fnp-3528	1055	28	promotes	promote	VERB
fnp-3528	1055	29	reverse	reverse	ADJ
fnp-3528	1055	30	cholesterol	cholesterol	NOUN
fnp-3528	1055	31	transport	transport	NOUN
fnp-3528	1055	32	and	and	CCONJ
fnp-3528	1055	33	induces	induce	VERB
fnp-3528	1055	34	formation	formation	NOUN
fnp-3528	1055	35	of	of	ADP
fnp-3528	1055	36	prebeta-1	prebeta-1	NUM
fnp-3528	1055	37	hdl	hdl	X
fnp-3528	1055	38	in	in	ADP
fnp-3528	1055	39	vitro	vitro	X
fnp-3528	1055	40	.	.	PUNCT
fnp-3528	1056	1	plos	plos	PROPN
fnp-3528	1056	2	one	one	NUM
fnp-3528	1056	3	2015	2015	NUM
fnp-3528	1056	4	,	,	PUNCT
fnp-3528	1056	5	10	10	NUM
fnp-3528	1056	6	,	,	PUNCT
fnp-3528	1056	7	e0131997	e0131997	NUM
fnp-3528	1056	8	.	.	PUNCT
fnp-3528	1057	1	boehm	boehm	PROPN
fnp-3528	1057	2	-	-	PUNCT
fnp-3528	1057	3	cagan	cagan	PROPN
fnp-3528	1057	4	,	,	PUNCT
fnp-3528	1057	5	a.	a.	NOUN
fnp-3528	1057	6	;	;	PUNCT
fnp-3528	1057	7	bar	bar	NOUN
fnp-3528	1057	8	,	,	PUNCT
fnp-3528	1057	9	r.	r.	PROPN
fnp-3528	1057	10	;	;	PUNCT
fnp-3528	1057	11	liraz	liraz	NOUN
fnp-3528	1057	12	,	,	PUNCT
fnp-3528	1057	13	o.	o.	PROPN
fnp-3528	1057	14	;	;	PUNCT
fnp-3528	1057	15	bielicki	bielicki	PROPN
fnp-3528	1057	16	,	,	PUNCT
fnp-3528	1057	17	j.	j.	PROPN
fnp-3528	1057	18	k.	k.	PROPN
fnp-3528	1057	19	;	;	PUNCT
fnp-3528	1057	20	johansson	johansson	PROPN
fnp-3528	1057	21	,	,	PUNCT
fnp-3528	1057	22	j.	j.	PROPN
fnp-3528	1057	23	o.	o.	PROPN
fnp-3528	1057	24	;	;	PUNCT
fnp-3528	1057	25	michaelson	michaelson	PROPN
fnp-3528	1057	26	,	,	PUNCT
fnp-3528	1057	27	d.	d.	PROPN
fnp-3528	1057	28	m.	m.	PROPN
fnp-3528	1057	29	abca1	abca1	PROPN
fnp-3528	1057	30	agonist	agonist	NOUN
fnp-3528	1057	31	reverses	reverse	VERB
fnp-3528	1057	32	the	the	DET
fnp-3528	1057	33	apoe4	apoe4	ADJ
fnp-3528	1057	34	-	-	PUNCT
fnp-3528	1057	35	driven	drive	VERB
fnp-3528	1057	36	cognitive	cognitive	ADJ
fnp-3528	1057	37	and	and	CCONJ
fnp-3528	1057	38	brain	brain	NOUN
fnp-3528	1057	39	pathologies	pathology	NOUN
fnp-3528	1057	40	.	.	PUNCT
fnp-3528	1058	1	j	j	PROPN
fnp-3528	1058	2	alzheimers	alzheimers	PROPN
fnp-3528	1058	3	dis	dis	PROPN
fnp-3528	1058	4	2016	2016	NUM
fnp-3528	1058	5	,	,	PUNCT
fnp-3528	1058	6	54	54	NUM
fnp-3528	1058	7	,	,	PUNCT
fnp-3528	1058	8	1219	1219	NUM
fnp-3528	1058	9	-	-	SYM
fnp-3528	1058	10	33	33	NUM
fnp-3528	1058	11	.	.	PUNCT
fnp-3528	1059	1	wang	wang	PROPN
fnp-3528	1059	2	,	,	PUNCT
fnp-3528	1059	3	l.	l.	PROPN
fnp-3528	1059	4	;	;	PUNCT
fnp-3528	1059	5	schuster	schuster	PROPN
fnp-3528	1059	6	,	,	PUNCT
fnp-3528	1059	7	g.	g.	PROPN
fnp-3528	1059	8	u.	u.	PROPN
fnp-3528	1059	9	;	;	PUNCT
fnp-3528	1059	10	hultenby	hultenby	PROPN
fnp-3528	1059	11	,	,	PUNCT
fnp-3528	1059	12	k.	k.	PROPN
fnp-3528	1059	13	;	;	PUNCT
fnp-3528	1059	14	zhang	zhang	PROPN
fnp-3528	1059	15	,	,	PUNCT
fnp-3528	1059	16	q.	q.	PROPN
fnp-3528	1059	17	;	;	PUNCT
fnp-3528	1059	18	andersson	andersson	PROPN
fnp-3528	1059	19	,	,	PUNCT
fnp-3528	1059	20	s.	s.	PROPN
fnp-3528	1059	21	;	;	PUNCT
fnp-3528	1059	22	gustafsson	gustafsson	PROPN
fnp-3528	1059	23	,	,	PUNCT
fnp-3528	1059	24	j.	j.	PROPN
fnp-3528	1059	25	a.	a.	PROPN
fnp-3528	1059	26	liver	liver	NOUN
fnp-3528	1059	27	x	x	NOUN
fnp-3528	1059	28	receptors	receptor	NOUN
fnp-3528	1059	29	in	in	ADP
fnp-3528	1059	30	the	the	DET
fnp-3528	1059	31	central	central	ADJ
fnp-3528	1059	32	nervous	nervous	ADJ
fnp-3528	1059	33	system	system	NOUN
fnp-3528	1059	34	:	:	PUNCT
fnp-3528	1059	35	from	from	ADP
fnp-3528	1059	36	lipid	lipid	NOUN
fnp-3528	1059	37	homeostasis	homeostasis	NOUN
fnp-3528	1059	38	to	to	ADP
fnp-3528	1059	39	neuronal	neuronal	ADJ
fnp-3528	1059	40	degeneration	degeneration	NOUN
fnp-3528	1059	41	.	.	PUNCT
fnp-3528	1060	1	proc	proc	PROPN
fnp-3528	1060	2	natl	natl	PROPN
fnp-3528	1060	3	acad	acad	PROPN
fnp-3528	1060	4	sci	sci	PROPN
fnp-3528	1060	5	u	u	PROPN
fnp-3528	1060	6	s	s	PROPN
fnp-3528	1060	7	a	a	DET
fnp-3528	1060	8	2002	2002	NUM
fnp-3528	1060	9	,	,	PUNCT
fnp-3528	1060	10	99	99	NUM
fnp-3528	1060	11	,	,	PUNCT
fnp-3528	1060	12	13878	13878	NUM
fnp-3528	1060	13	-	-	SYM
fnp-3528	1060	14	83	83	NUM
fnp-3528	1060	15	.	.	PUNCT
fnp-3528	1061	1	santamarina	santamarina	NOUN
fnp-3528	1061	2	-	-	PUNCT
fnp-3528	1061	3	fojo	fojo	NOUN
fnp-3528	1061	4	,	,	PUNCT
fnp-3528	1061	5	s.	s.	PROPN
fnp-3528	1061	6	;	;	PUNCT
fnp-3528	1061	7	remaley	remaley	PROPN
fnp-3528	1061	8	,	,	PUNCT
fnp-3528	1061	9	a.	a.	NOUN
fnp-3528	1061	10	t.	t.	PROPN
fnp-3528	1061	11	;	;	PUNCT
fnp-3528	1061	12	neufeld	neufeld	PROPN
fnp-3528	1061	13	,	,	PUNCT
fnp-3528	1061	14	e.	e.	PROPN
fnp-3528	1061	15	b.	b.	PROPN
fnp-3528	1061	16	;	;	PUNCT
fnp-3528	1061	17	brewer	brewer	PROPN
fnp-3528	1061	18	,	,	PUNCT
fnp-3528	1061	19	h.	h.	PROPN
fnp-3528	1061	20	b.	b.	PROPN
fnp-3528	1061	21	,	,	PUNCT
fnp-3528	1061	22	jr	jr	PROPN
fnp-3528	1061	23	.	.	PROPN
fnp-3528	1061	24	regulation	regulation	NOUN
fnp-3528	1061	25	and	and	CCONJ
fnp-3528	1061	26	intracellular	intracellular	ADJ
fnp-3528	1061	27	trafficking	trafficking	NOUN
fnp-3528	1061	28	of	of	ADP
fnp-3528	1061	29	the	the	DET
fnp-3528	1061	30	abca1	abca1	NOUN
fnp-3528	1061	31	transporter	transporter	NOUN
fnp-3528	1061	32	.	.	PUNCT
fnp-3528	1062	1	j	j	PROPN
fnp-3528	1062	2	lipid	lipid	PROPN
fnp-3528	1062	3	res	re	NOUN
fnp-3528	1062	4	2001	2001	NUM
fnp-3528	1062	5	,	,	PUNCT
fnp-3528	1062	6	42	42	NUM
fnp-3528	1062	7	,	,	PUNCT
fnp-3528	1062	8	1339	1339	NUM
fnp-3528	1062	9	-	-	SYM
fnp-3528	1062	10	45	45	NUM
fnp-3528	1062	11	.	.	PUNCT
fnp-3528	1063	1	repa	repa	PROPN
fnp-3528	1063	2	,	,	PUNCT
fnp-3528	1063	3	j.	j.	PROPN
fnp-3528	1063	4	j.	j.	PROPN
fnp-3528	1063	5	;	;	PUNCT
fnp-3528	1063	6	turley	turley	PROPN
fnp-3528	1063	7	,	,	PUNCT
fnp-3528	1063	8	s.	s.	PROPN
fnp-3528	1063	9	d.	d.	PROPN
fnp-3528	1063	10	;	;	PUNCT
fnp-3528	1063	11	lobaccaro	lobaccaro	PROPN
fnp-3528	1063	12	,	,	PUNCT
fnp-3528	1063	13	j.	j.	PROPN
fnp-3528	1063	14	a.	a.	PROPN
fnp-3528	1063	15	;	;	PUNCT
fnp-3528	1063	16	medina	medina	PROPN
fnp-3528	1063	17	,	,	PUNCT
fnp-3528	1063	18	j.	j.	PROPN
fnp-3528	1063	19	;	;	PUNCT
fnp-3528	1063	20	li	li	PROPN
fnp-3528	1063	21	,	,	PUNCT
fnp-3528	1063	22	l.	l.	PROPN
fnp-3528	1063	23	;	;	PUNCT
fnp-3528	1063	24	lustig	lustig	PROPN
fnp-3528	1063	25	,	,	PUNCT
fnp-3528	1063	26	k.	k.	PROPN
fnp-3528	1063	27	;	;	PUNCT
fnp-3528	1063	28	shan	shan	PROPN
fnp-3528	1063	29	,	,	PUNCT
fnp-3528	1063	30	b.	b.	PROPN
fnp-3528	1063	31	;	;	PUNCT
fnp-3528	1063	32	heyman	heyman	PROPN
fnp-3528	1063	33	,	,	PUNCT
fnp-3528	1063	34	r.	r.	PROPN
fnp-3528	1063	35	a.	a.	PROPN
fnp-3528	1063	36	;	;	PUNCT
fnp-3528	1063	37	dietschy	dietschy	ADJ
fnp-3528	1063	38	,	,	PUNCT
fnp-3528	1063	39	j.	j.	PROPN
fnp-3528	1063	40	m.	m.	PROPN
fnp-3528	1063	41	;	;	PUNCT
fnp-3528	1063	42	mangelsdorf	mangelsdorf	PROPN
fnp-3528	1063	43	,	,	PUNCT
fnp-3528	1063	44	d.	d.	PROPN
fnp-3528	1063	45	j.	j.	PROPN
fnp-3528	1063	46	regulation	regulation	PROPN
fnp-3528	1063	47	of	of	ADP
fnp-3528	1063	48	absorption	absorption	NOUN
fnp-3528	1063	49	and	and	CCONJ
fnp-3528	1063	50	abc1	abc1	PROPN
fnp-3528	1063	51	-	-	PUNCT
fnp-3528	1063	52	mediated	mediate	VERB
fnp-3528	1063	53	efflux	efflux	NOUN
fnp-3528	1063	54	of	of	ADP
fnp-3528	1063	55	cholesterol	cholesterol	NOUN
fnp-3528	1063	56	by	by	ADP
fnp-3528	1063	57	rxr	rxr	PROPN
fnp-3528	1063	58	heterodimers	heterodimers	PROPN
fnp-3528	1063	59	.	.	PUNCT
fnp-3528	1064	1	science	science	NOUN
fnp-3528	1064	2	2000	2000	NUM
fnp-3528	1064	3	,	,	PUNCT
fnp-3528	1064	4	289	289	NUM
fnp-3528	1064	5	,	,	PUNCT
fnp-3528	1064	6	1524	1524	NUM
fnp-3528	1064	7	-	-	SYM
fnp-3528	1064	8	9	9	NUM
fnp-3528	1064	9	.	.	PUNCT
fnp-3528	1065	1	cramer	cramer	PROPN
fnp-3528	1065	2	,	,	PUNCT
fnp-3528	1065	3	p.	p.	PROPN
fnp-3528	1065	4	e.	e.	PROPN
fnp-3528	1065	5	;	;	PUNCT
fnp-3528	1065	6	cirrito	cirrito	PROPN
fnp-3528	1065	7	,	,	PUNCT
fnp-3528	1065	8	j.	j.	PROPN
fnp-3528	1065	9	r.	r.	PROPN
fnp-3528	1065	10	;	;	PUNCT
fnp-3528	1065	11	wesson	wesson	PROPN
fnp-3528	1065	12	,	,	PUNCT
fnp-3528	1065	13	d.	d.	PROPN
fnp-3528	1065	14	w.	w.	PROPN
fnp-3528	1065	15	;	;	PUNCT
fnp-3528	1065	16	lee	lee	PROPN
fnp-3528	1065	17	,	,	PUNCT
fnp-3528	1065	18	c.	c.	PROPN
fnp-3528	1065	19	y.	y.	PROPN
fnp-3528	1065	20	;	;	PUNCT
fnp-3528	1065	21	karlo	karlo	PROPN
fnp-3528	1065	22	,	,	PUNCT
fnp-3528	1065	23	j.	j.	PROPN
fnp-3528	1065	24	c.	c.	PROPN
fnp-3528	1065	25	;	;	PUNCT
fnp-3528	1065	26	zinn	zinn	PROPN
fnp-3528	1065	27	,	,	PUNCT
fnp-3528	1065	28	a.	a.	PROPN
fnp-3528	1065	29	e.	e.	PROPN
fnp-3528	1065	30	;	;	PUNCT
fnp-3528	1065	31	casali	casali	PROPN
fnp-3528	1065	32	,	,	PUNCT
fnp-3528	1065	33	b.	b.	PROPN
fnp-3528	1065	34	t.	t.	PROPN
fnp-3528	1065	35	;	;	PUNCT
fnp-3528	1065	36	restivo	restivo	PROPN
fnp-3528	1065	37	,	,	PUNCT
fnp-3528	1065	38	j.	j.	PROPN
fnp-3528	1065	39	l.	l.	PROPN
fnp-3528	1065	40	;	;	PUNCT
fnp-3528	1065	41	goebel	goebel	PROPN
fnp-3528	1065	42	,	,	PUNCT
fnp-3528	1065	43	w.	w.	PROPN
fnp-3528	1065	44	d.	d.	PROPN
fnp-3528	1065	45	;	;	PUNCT
fnp-3528	1065	46	james	james	PROPN
fnp-3528	1065	47	,	,	PUNCT
fnp-3528	1065	48	m.	m.	PROPN
fnp-3528	1065	49	j.	j.	PROPN
fnp-3528	1065	50	;	;	PUNCT
fnp-3528	1065	51	brunden	brunden	PROPN
fnp-3528	1065	52	,	,	PUNCT
fnp-3528	1065	53	k.	k.	PROPN
fnp-3528	1065	54	r.	r.	PROPN
fnp-3528	1065	55	;	;	PUNCT
fnp-3528	1066	1	wilson	wilson	PROPN
fnp-3528	1066	2	,	,	PUNCT
fnp-3528	1066	3	d.	d.	PROPN
fnp-3528	1066	4	a.	a.	PROPN
fnp-3528	1066	5	;	;	PUNCT
fnp-3528	1066	6	landreth	landreth	PROPN
fnp-3528	1066	7	,	,	PUNCT
fnp-3528	1066	8	g.	g.	PROPN
fnp-3528	1066	9	e.	e.	PROPN
fnp-3528	1066	10	apoe	apoe	PROPN
fnp-3528	1066	11	-	-	PUNCT
fnp-3528	1066	12	directed	direct	VERB
fnp-3528	1066	13	therapeutics	therapeutic	NOUN
fnp-3528	1066	14	rapidly	rapidly	ADV
fnp-3528	1066	15	clear	clear	VERB
fnp-3528	1066	16	beta	beta	NOUN
fnp-3528	1066	17	-	-	PUNCT
fnp-3528	1066	18	amyloid	amyloid	NOUN
fnp-3528	1066	19	and	and	CCONJ
fnp-3528	1066	20	reverse	reverse	ADJ
fnp-3528	1066	21	deficits	deficit	NOUN
fnp-3528	1066	22	in	in	ADP
fnp-3528	1066	23	ad	ad	NOUN
fnp-3528	1066	24	mouse	mouse	NOUN
fnp-3528	1066	25	models	model	NOUN
fnp-3528	1066	26	.	.	PUNCT
fnp-3528	1067	1	science	science	NOUN
fnp-3528	1067	2	2012	2012	NUM
fnp-3528	1067	3	,	,	PUNCT
fnp-3528	1067	4	335	335	NUM
fnp-3528	1067	5	,	,	PUNCT
fnp-3528	1067	6	1503	1503	NUM
fnp-3528	1067	7	-	-	SYM
fnp-3528	1067	8	6	6	NUM
fnp-3528	1067	9	.	.	PUNCT
fnp-3528	1067	10	terwel	terwel	PROPN
fnp-3528	1067	11	,	,	PUNCT
fnp-3528	1067	12	d.	d.	PROPN
fnp-3528	1067	13	;	;	PUNCT
fnp-3528	1067	14	steffensen	steffensen	PROPN
fnp-3528	1067	15	,	,	PUNCT
fnp-3528	1067	16	k.	k.	PROPN
fnp-3528	1067	17	r.	r.	PROPN
fnp-3528	1067	18	;	;	PUNCT
fnp-3528	1067	19	verghese	verghese	PROPN
fnp-3528	1067	20	,	,	PUNCT
fnp-3528	1067	21	p.	p.	PROPN
fnp-3528	1067	22	b.	b.	PROPN
fnp-3528	1067	23	;	;	PUNCT
fnp-3528	1068	1	kummer	kummer	NOUN
fnp-3528	1068	2	,	,	PUNCT
fnp-3528	1068	3	m.	m.	NOUN
fnp-3528	1068	4	p.	p.	NOUN
fnp-3528	1068	5	;	;	PUNCT
fnp-3528	1068	6	gustafsson	gustafsson	PROPN
fnp-3528	1068	7	,	,	PUNCT
fnp-3528	1068	8	j.	j.	PROPN
fnp-3528	1068	9	a.	a.	PROPN
fnp-3528	1068	10	;	;	PUNCT
fnp-3528	1068	11	holtzman	holtzman	NOUN
fnp-3528	1068	12	,	,	PUNCT
fnp-3528	1068	13	d.	d.	PROPN
fnp-3528	1068	14	m.	m.	PROPN
fnp-3528	1068	15	;	;	PUNCT
fnp-3528	1068	16	heneka	heneka	PROPN
fnp-3528	1068	17	,	,	PUNCT
fnp-3528	1068	18	m.	m.	NOUN
fnp-3528	1068	19	t.	t.	NOUN
fnp-3528	1068	20	critical	critical	ADJ
fnp-3528	1068	21	role	role	NOUN
fnp-3528	1068	22	of	of	ADP
fnp-3528	1068	23	astroglial	astroglial	ADJ
fnp-3528	1068	24	apolipoprotein	apolipoprotein	ADJ
fnp-3528	1068	25	e	e	NOUN
fnp-3528	1068	26	and	and	CCONJ
fnp-3528	1068	27	liver	liver	NOUN
fnp-3528	1068	28	x	x	SYM
fnp-3528	1068	29	receptor	receptor	NOUN
fnp-3528	1068	30	-	-	PUNCT
fnp-3528	1068	31	alpha	alpha	NOUN
fnp-3528	1068	32	expression	expression	NOUN
fnp-3528	1068	33	for	for	ADP
fnp-3528	1068	34	microglial	microglial	ADJ
fnp-3528	1068	35	abeta	abeta	ADJ
fnp-3528	1068	36	phagocytosis	phagocytosis	NOUN
fnp-3528	1068	37	.	.	PUNCT
fnp-3528	1069	1	j	j	PROPN
fnp-3528	1069	2	neurosci	neurosci	PROPN
fnp-3528	1069	3	2011	2011	NUM
fnp-3528	1069	4	,	,	PUNCT
fnp-3528	1069	5	31	31	NUM
fnp-3528	1069	6	,	,	PUNCT
fnp-3528	1069	7	7049	7049	NUM
fnp-3528	1069	8	-	-	SYM
fnp-3528	1069	9	59	59	NUM
fnp-3528	1069	10	.	.	PUNCT
fnp-3528	1070	1	lefterov	lefterov	PROPN
fnp-3528	1070	2	,	,	PUNCT
fnp-3528	1070	3	i.	i.	PROPN
fnp-3528	1070	4	;	;	PUNCT
fnp-3528	1070	5	bookout	bookout	PROPN
fnp-3528	1070	6	,	,	PUNCT
fnp-3528	1070	7	a.	a.	PROPN
fnp-3528	1070	8	;	;	PUNCT
fnp-3528	1070	9	wang	wang	PROPN
fnp-3528	1070	10	,	,	PUNCT
fnp-3528	1070	11	z.	z.	PROPN
fnp-3528	1070	12	;	;	PUNCT
fnp-3528	1070	13	staufenbiel	staufenbiel	PROPN
fnp-3528	1070	14	,	,	PUNCT
fnp-3528	1070	15	m.	m.	NOUN
fnp-3528	1070	16	;	;	PUNCT
fnp-3528	1070	17	mangelsdorf	mangelsdorf	PROPN
fnp-3528	1070	18	,	,	PUNCT
fnp-3528	1070	19	d.	d.	PROPN
fnp-3528	1070	20	;	;	PUNCT
fnp-3528	1070	21	koldamova	koldamova	PROPN
fnp-3528	1070	22	,	,	PUNCT
fnp-3528	1070	23	r.	r.	NOUN
fnp-3528	1070	24	expression	expression	NOUN
fnp-3528	1070	25	profiling	profiling	NOUN
fnp-3528	1070	26	in	in	ADP
fnp-3528	1070	27	app23	app23	PROPN
fnp-3528	1070	28	mouse	mouse	NOUN
fnp-3528	1070	29	brain	brain	NOUN
fnp-3528	1070	30	:	:	PUNCT
fnp-3528	1070	31	inhibition	inhibition	NOUN
fnp-3528	1070	32	of	of	ADP
fnp-3528	1070	33	abeta	abeta	NOUN
fnp-3528	1070	34	amyloidosis	amyloidosis	NOUN
fnp-3528	1070	35	and	and	CCONJ
fnp-3528	1070	36	inflammation	inflammation	NOUN
fnp-3528	1070	37	in	in	ADP
fnp-3528	1070	38	response	response	NOUN
fnp-3528	1070	39	to	to	ADP
fnp-3528	1070	40	lxr	lxr	PROPN
fnp-3528	1070	41	agonist	agonist	NOUN
fnp-3528	1070	42	treatment	treatment	NOUN
fnp-3528	1070	43	.	.	PUNCT
fnp-3528	1071	1	mol	mol	ADP
fnp-3528	1071	2	neurodegener	neurodegener	NOUN
fnp-3528	1071	3	2007	2007	NUM
fnp-3528	1071	4	,	,	PUNCT
fnp-3528	1071	5	2	2	NUM
fnp-3528	1071	6	,	,	PUNCT
fnp-3528	1071	7	20	20	NUM
fnp-3528	1071	8	.	.	PUNCT
fnp-3528	1072	1	riddell	riddell	PROPN
fnp-3528	1072	2	,	,	PUNCT
fnp-3528	1072	3	d.	d.	PROPN
fnp-3528	1072	4	r.	r.	PROPN
fnp-3528	1072	5	;	;	PUNCT
fnp-3528	1072	6	zhou	zhou	PROPN
fnp-3528	1072	7	,	,	PUNCT
fnp-3528	1072	8	h.	h.	PROPN
fnp-3528	1072	9	;	;	PUNCT
fnp-3528	1072	10	comery	comery	NOUN
fnp-3528	1072	11	,	,	PUNCT
fnp-3528	1072	12	t.	t.	PROPN
fnp-3528	1072	13	a.	a.	PROPN
fnp-3528	1072	14	;	;	PUNCT
fnp-3528	1072	15	kouranova	kouranova	PROPN
fnp-3528	1072	16	,	,	PUNCT
fnp-3528	1072	17	e.	e.	PROPN
fnp-3528	1072	18	;	;	PUNCT
fnp-3528	1072	19	lo	lo	PROPN
fnp-3528	1072	20	,	,	PUNCT
fnp-3528	1072	21	c.	c.	PROPN
fnp-3528	1072	22	f.	f.	PROPN
fnp-3528	1072	23	;	;	PUNCT
fnp-3528	1072	24	warwick	warwick	PROPN
fnp-3528	1072	25	,	,	PUNCT
fnp-3528	1072	26	h.	h.	PROPN
fnp-3528	1072	27	k.	k.	PROPN
fnp-3528	1072	28	;	;	PUNCT
fnp-3528	1072	29	ring	ring	PROPN
fnp-3528	1072	30	,	,	PUNCT
fnp-3528	1072	31	r.	r.	PROPN
fnp-3528	1072	32	h.	h.	PROPN
fnp-3528	1072	33	;	;	PUNCT
fnp-3528	1072	34	kirksey	kirksey	ADJ
fnp-3528	1072	35	,	,	PUNCT
fnp-3528	1072	36	y.	y.	PROPN
fnp-3528	1072	37	;	;	PUNCT
fnp-3528	1072	38	aschmies	aschmie	NOUN
fnp-3528	1072	39	,	,	PUNCT
fnp-3528	1072	40	s.	s.	PROPN
fnp-3528	1072	41	;	;	PUNCT
fnp-3528	1072	42	xu	xu	PROPN
fnp-3528	1072	43	,	,	PUNCT
fnp-3528	1072	44	j.	j.	PROPN
fnp-3528	1072	45	;	;	PUNCT
fnp-3528	1072	46	kubek	kubek	PROPN
fnp-3528	1072	47	,	,	PUNCT
fnp-3528	1072	48	k.	k.	PROPN
fnp-3528	1072	49	;	;	PUNCT
fnp-3528	1072	50	hirst	hirst	PROPN
fnp-3528	1072	51	,	,	PUNCT
fnp-3528	1072	52	w.	w.	PROPN
fnp-3528	1072	53	d.	d.	PROPN
fnp-3528	1072	54	;	;	PUNCT
fnp-3528	1072	55	gonzales	gonzales	PROPN
fnp-3528	1072	56	,	,	PUNCT
fnp-3528	1072	57	c.	c.	PROPN
fnp-3528	1072	58	;	;	PUNCT
fnp-3528	1072	59	chen	chen	PROPN
fnp-3528	1072	60	,	,	PUNCT
fnp-3528	1072	61	y.	y.	PROPN
fnp-3528	1072	62	;	;	PUNCT
fnp-3528	1072	63	murphy	murphy	PROPN
fnp-3528	1072	64	,	,	PUNCT
fnp-3528	1072	65	e.	e.	PROPN
fnp-3528	1072	66	;	;	PUNCT
fnp-3528	1072	67	leonard	leonard	PROPN
fnp-3528	1072	68	,	,	PUNCT
fnp-3528	1072	69	s.	s.	PROPN
fnp-3528	1072	70	;	;	PUNCT
fnp-3528	1072	71	vasylyev	vasylyev	PROPN
fnp-3528	1072	72	,	,	PUNCT
fnp-3528	1072	73	d.	d.	PROPN
fnp-3528	1072	74	;	;	PUNCT
fnp-3528	1072	75	oganesian	oganesian	ADJ
fnp-3528	1072	76	,	,	PUNCT
fnp-3528	1072	77	a.	a.	NOUN
fnp-3528	1072	78	;	;	PUNCT
fnp-3528	1072	79	martone	martone	NOUN
fnp-3528	1072	80	,	,	PUNCT
fnp-3528	1072	81	r.	r.	PROPN
fnp-3528	1072	82	l.	l.	PROPN
fnp-3528	1072	83	;	;	PUNCT
fnp-3528	1072	84	pangalos	pangalo	NOUN
fnp-3528	1072	85	,	,	PUNCT
fnp-3528	1072	86	m.	m.	NOUN
fnp-3528	1072	87	n.	n.	PROPN
fnp-3528	1072	88	;	;	PUNCT
fnp-3528	1072	89	reinhart	reinhart	PROPN
fnp-3528	1072	90	,	,	PUNCT
fnp-3528	1072	91	p.	p.	PROPN
fnp-3528	1072	92	h.	h.	PROPN
fnp-3528	1072	93	;	;	PUNCT
fnp-3528	1072	94	jacobsen	jacobsen	PROPN
fnp-3528	1072	95	,	,	PUNCT
fnp-3528	1072	96	j.	j.	PROPN
fnp-3528	1072	97	s.	s.	PROPN
fnp-3528	1073	1	the	the	DET
fnp-3528	1073	2	lxr	lxr	PROPN
fnp-3528	1073	3	agonist	agonist	NOUN
fnp-3528	1073	4	to901317	to901317	NOUN
fnp-3528	1073	5	selectively	selectively	ADV
fnp-3528	1073	6	lowers	lower	VERB
fnp-3528	1073	7	hippocampal	hippocampal	ADJ
fnp-3528	1073	8	abeta42	abeta42	NOUN
fnp-3528	1073	9	and	and	CCONJ
fnp-3528	1073	10	improves	improve	VERB
fnp-3528	1073	11	memory	memory	NOUN
fnp-3528	1073	12	in	in	ADP
fnp-3528	1073	13	the	the	DET
fnp-3528	1073	14	tg2576	tg2576	PROPN
fnp-3528	1073	15	mouse	mouse	NOUN
fnp-3528	1073	16	model	model	NOUN
fnp-3528	1073	17	of	of	ADP
fnp-3528	1073	18	alzheimer	alzheimer	PROPN
fnp-3528	1073	19	's	's	PART
fnp-3528	1073	20	disease	disease	NOUN
fnp-3528	1073	21	.	.	PUNCT
fnp-3528	1074	1	mol	mol	ADP
fnp-3528	1074	2	cell	cell	NOUN
fnp-3528	1074	3	neurosci	neurosci	NOUN
fnp-3528	1074	4	2007	2007	NUM
fnp-3528	1074	5	,	,	PUNCT
fnp-3528	1074	6	34	34	NUM
fnp-3528	1074	7	,	,	PUNCT
fnp-3528	1074	8	621	621	NUM
fnp-3528	1074	9	-	-	SYM
fnp-3528	1074	10	8	8	NUM
fnp-3528	1074	11	.	.	PUNCT
fnp-3528	1075	1	koldamova	koldamova	PROPN
fnp-3528	1075	2	,	,	PUNCT
fnp-3528	1075	3	r.	r.	PROPN
fnp-3528	1075	4	p.	p.	PROPN
fnp-3528	1075	5	;	;	PUNCT
fnp-3528	1075	6	lefterov	lefterov	PROPN
fnp-3528	1075	7	,	,	PUNCT
fnp-3528	1075	8	i.	i.	NOUN
fnp-3528	1075	9	m.	m.	NOUN
fnp-3528	1075	10	;	;	PUNCT
fnp-3528	1075	11	staufenbiel	staufenbiel	PROPN
fnp-3528	1075	12	,	,	PUNCT
fnp-3528	1075	13	m.	m.	NOUN
fnp-3528	1075	14	;	;	PUNCT
fnp-3528	1075	15	wolfe	wolfe	PROPN
fnp-3528	1075	16	,	,	PUNCT
fnp-3528	1075	17	d.	d.	PROPN
fnp-3528	1075	18	;	;	PUNCT
fnp-3528	1075	19	huang	huang	PROPN
fnp-3528	1075	20	,	,	PUNCT
fnp-3528	1075	21	s.	s.	PROPN
fnp-3528	1075	22	;	;	PUNCT
fnp-3528	1075	23	glorioso	glorioso	PROPN
fnp-3528	1075	24	,	,	PUNCT
fnp-3528	1075	25	j.	j.	PROPN
fnp-3528	1075	26	c.	c.	PROPN
fnp-3528	1075	27	;	;	PUNCT
fnp-3528	1075	28	walter	walter	PROPN
fnp-3528	1075	29	,	,	PUNCT
fnp-3528	1075	30	m.	m.	NOUN
fnp-3528	1075	31	;	;	PUNCT
fnp-3528	1075	32	roth	roth	PROPN
fnp-3528	1075	33	,	,	PUNCT
fnp-3528	1075	34	m.	m.	NOUN
fnp-3528	1075	35	g.	g.	PROPN
fnp-3528	1075	36	;	;	PUNCT
fnp-3528	1075	37	lazo	lazo	PROPN
fnp-3528	1075	38	,	,	PUNCT
fnp-3528	1075	39	j.	j.	PROPN
fnp-3528	1075	40	s.	s.	PROPN
fnp-3528	1075	41	the	the	DET
fnp-3528	1075	42	liver	liver	NOUN
fnp-3528	1075	43	x	x	ADP
fnp-3528	1075	44	receptor	receptor	NOUN
fnp-3528	1075	45	ligand	ligand	NOUN
fnp-3528	1075	46	t0901317	t0901317	PROPN
fnp-3528	1075	47	decreases	decrease	VERB
fnp-3528	1075	48	amyloid	amyloid	NOUN
fnp-3528	1075	49	beta	beta	ADJ
fnp-3528	1075	50	production	production	NOUN
fnp-3528	1075	51	in	in	ADP
fnp-3528	1075	52	vitro	vitro	X
fnp-3528	1075	53	and	and	CCONJ
fnp-3528	1075	54	in	in	ADP
fnp-3528	1075	55	a	a	DET
fnp-3528	1075	56	mouse	mouse	NOUN
fnp-3528	1075	57	model	model	NOUN
fnp-3528	1075	58	of	of	ADP
fnp-3528	1075	59	alzheimer	alzheimer	PROPN
fnp-3528	1075	60	's	's	PART
fnp-3528	1075	61	disease	disease	NOUN
fnp-3528	1075	62	.	.	PUNCT
fnp-3528	1076	1	j	j	PROPN
fnp-3528	1076	2	biol	biol	PROPN
fnp-3528	1076	3	chem	chem	NOUN
fnp-3528	1076	4	2005	2005	NUM
fnp-3528	1076	5	,	,	PUNCT
fnp-3528	1076	6	280	280	NUM
fnp-3528	1076	7	,	,	PUNCT
fnp-3528	1076	8	4079	4079	NUM
fnp-3528	1076	9	-	-	SYM
fnp-3528	1076	10	88	88	NUM
fnp-3528	1076	11	.	.	PUNCT
fnp-3528	1077	1	donkin	donkin	PROPN
fnp-3528	1077	2	,	,	PUNCT
fnp-3528	1077	3	j.	j.	PROPN
fnp-3528	1077	4	j.	j.	PROPN
fnp-3528	1077	5	;	;	PUNCT
fnp-3528	1077	6	stukas	stukas	PROPN
fnp-3528	1077	7	,	,	PUNCT
fnp-3528	1077	8	s.	s.	PROPN
fnp-3528	1077	9	;	;	PUNCT
fnp-3528	1077	10	hirsch	hirsch	PROPN
fnp-3528	1077	11	-	-	PUNCT
fnp-3528	1077	12	reinshagen	reinshagen	NOUN
fnp-3528	1077	13	,	,	PUNCT
fnp-3528	1077	14	v.	v.	ADV
fnp-3528	1077	15	;	;	PUNCT
fnp-3528	1077	16	namjoshi	namjoshi	PROPN
fnp-3528	1077	17	,	,	PUNCT
fnp-3528	1077	18	d.	d.	PROPN
fnp-3528	1077	19	;	;	PUNCT
fnp-3528	1077	20	wilkinson	wilkinson	PROPN
fnp-3528	1077	21	,	,	PUNCT
fnp-3528	1077	22	a.	a.	PROPN
fnp-3528	1077	23	;	;	PUNCT
fnp-3528	1077	24	may	may	AUX
fnp-3528	1077	25	,	,	PUNCT
fnp-3528	1077	26	s.	s.	PROPN
fnp-3528	1077	27	;	;	PUNCT
fnp-3528	1077	28	chan	chan	PROPN
fnp-3528	1077	29	,	,	PUNCT
fnp-3528	1077	30	j.	j.	PROPN
fnp-3528	1077	31	;	;	PUNCT
fnp-3528	1077	32	fan	fan	PROPN
fnp-3528	1077	33	,	,	PUNCT
fnp-3528	1077	34	j.	j.	PROPN
fnp-3528	1077	35	;	;	PUNCT
fnp-3528	1077	36	collins	collins	PROPN
fnp-3528	1077	37	,	,	PUNCT
fnp-3528	1077	38	j.	j.	PROPN
fnp-3528	1077	39	;	;	PUNCT
fnp-3528	1077	40	wellington	wellington	PROPN
fnp-3528	1077	41	,	,	PUNCT
fnp-3528	1077	42	c.	c.	PROPN
fnp-3528	1077	43	l.	l.	PROPN
fnp-3528	1077	44	atp	atp	PROPN
fnp-3528	1077	45	-	-	PUNCT
fnp-3528	1077	46	binding	bind	VERB
fnp-3528	1077	47	cassette	cassette	NOUN
fnp-3528	1077	48	transporter	transporter	NOUN
fnp-3528	1077	49	a1	a1	NOUN
fnp-3528	1077	50	mediates	mediate	NOUN
fnp-3528	1077	51	the	the	DET
fnp-3528	1077	52	beneficial	beneficial	ADJ
fnp-3528	1077	53	effects	effect	NOUN
fnp-3528	1077	54	of	of	ADP
fnp-3528	1077	55	the	the	DET
fnp-3528	1077	56	liver	liver	NOUN
fnp-3528	1077	57	x	x	PUNCT
fnp-3528	1077	58	receptor	receptor	NOUN
fnp-3528	1077	59	agonist	agonist	NOUN
fnp-3528	1077	60	gw3965	gw3965	NOUN
fnp-3528	1077	61	on	on	ADP
fnp-3528	1077	62	object	object	NOUN
fnp-3528	1077	63	recognition	recognition	NOUN
fnp-3528	1077	64	memory	memory	NOUN
fnp-3528	1077	65	and	and	CCONJ
fnp-3528	1077	66	amyloid	amyloid	NOUN
fnp-3528	1077	67	burden	burden	NOUN
fnp-3528	1077	68	in	in	ADP
fnp-3528	1077	69	amyloid	amyloid	NOUN
fnp-3528	1077	70	precursor	precursor	NOUN
fnp-3528	1077	71	protein	protein	NOUN
fnp-3528	1077	72	/	/	SYM
fnp-3528	1077	73	presenilin	presenilin	PROPN
fnp-3528	1077	74	1	1	NUM
fnp-3528	1077	75	mice	mouse	NOUN
fnp-3528	1077	76	.	.	PUNCT
fnp-3528	1078	1	j	j	PROPN
fnp-3528	1078	2	biol	biol	PROPN
fnp-3528	1078	3	chem	chem	NOUN
fnp-3528	1078	4	2010	2010	NUM
fnp-3528	1078	5	,	,	PUNCT
fnp-3528	1078	6	285	285	NUM
fnp-3528	1078	7	,	,	PUNCT
fnp-3528	1078	8	34144	34144	NUM
fnp-3528	1078	9	-	-	SYM
fnp-3528	1078	10	54	54	NUM
fnp-3528	1078	11	.	.	PUNCT
fnp-3528	1079	1	vanmierlo	vanmierlo	NOUN
fnp-3528	1079	2	,	,	PUNCT
fnp-3528	1079	3	t.	t.	PROPN
fnp-3528	1079	4	;	;	PUNCT
fnp-3528	1079	5	rutten	rutten	PROPN
fnp-3528	1079	6	,	,	PUNCT
fnp-3528	1079	7	k.	k.	PROPN
fnp-3528	1079	8	;	;	PUNCT
fnp-3528	1079	9	dederen	dederen	PROPN
fnp-3528	1079	10	,	,	PUNCT
fnp-3528	1079	11	j.	j.	PROPN
fnp-3528	1079	12	;	;	PUNCT
fnp-3528	1079	13	bloks	bloks	PROPN
fnp-3528	1079	14	,	,	PUNCT
fnp-3528	1079	15	v.	v.	PROPN
fnp-3528	1079	16	w.	w.	PROPN
fnp-3528	1079	17	;	;	PUNCT
fnp-3528	1079	18	van	van	PROPN
fnp-3528	1079	19	vark	vark	PROPN
fnp-3528	1079	20	-	-	PUNCT
fnp-3528	1079	21	van	van	PROPN
fnp-3528	1079	22	der	der	PROPN
fnp-3528	1079	23	zee	zee	PROPN
fnp-3528	1079	24	,	,	PUNCT
fnp-3528	1079	25	l.	l.	PROPN
fnp-3528	1079	26	c.	c.	PROPN
fnp-3528	1079	27	;	;	PUNCT
fnp-3528	1079	28	kuipers	kuiper	NOUN
fnp-3528	1079	29	,	,	PUNCT
fnp-3528	1079	30	f.	f.	PROPN
fnp-3528	1079	31	;	;	PUNCT
fnp-3528	1079	32	kiliaan	kiliaan	PROPN
fnp-3528	1079	33	,	,	PUNCT
fnp-3528	1079	34	a.	a.	NOUN
fnp-3528	1079	35	;	;	PUNCT
fnp-3528	1079	36	blokland	blokland	PROPN
fnp-3528	1079	37	,	,	PUNCT
fnp-3528	1079	38	a.	a.	NOUN
fnp-3528	1079	39	;	;	PUNCT
fnp-3528	1079	40	sijbrands	sijbrand	NOUN
fnp-3528	1079	41	,	,	PUNCT
fnp-3528	1079	42	e.	e.	PROPN
fnp-3528	1079	43	j.	j.	PROPN
fnp-3528	1079	44	;	;	PUNCT
fnp-3528	1079	45	steinbusch	steinbusch	PROPN
fnp-3528	1079	46	,	,	PUNCT
fnp-3528	1079	47	h.	h.	PROPN
fnp-3528	1079	48	;	;	PUNCT
fnp-3528	1079	49	prickaerts	prickaert	NOUN
fnp-3528	1079	50	,	,	PUNCT
fnp-3528	1079	51	j.	j.	PROPN
fnp-3528	1079	52	;	;	PUNCT
fnp-3528	1079	53	lutjohann	lutjohann	PROPN
fnp-3528	1079	54	,	,	PUNCT
fnp-3528	1079	55	d.	d.	PROPN
fnp-3528	1079	56	;	;	PUNCT
fnp-3528	1079	57	mulder	mulder	PROPN
fnp-3528	1079	58	,	,	PUNCT
fnp-3528	1079	59	m.	m.	NOUN
fnp-3528	1079	60	liver	liver	NOUN
fnp-3528	1079	61	x	x	SYM
fnp-3528	1079	62	receptor	receptor	NOUN
fnp-3528	1079	63	activation	activation	NOUN
fnp-3528	1079	64	restores	restore	VERB
fnp-3528	1079	65	memory	memory	NOUN
fnp-3528	1079	66	in	in	ADP
fnp-3528	1079	67	aged	aged	ADJ
fnp-3528	1079	68	ad	ad	NOUN
fnp-3528	1079	69	mice	mouse	NOUN
fnp-3528	1079	70	without	without	ADP
fnp-3528	1079	71	reducing	reduce	VERB
fnp-3528	1079	72	amyloid	amyloid	NOUN
fnp-3528	1079	73	.	.	PUNCT
fnp-3528	1080	1	neurobiol	neurobiol	NOUN
fnp-3528	1080	2	aging	age	VERB
fnp-3528	1080	3	2011	2011	NUM
fnp-3528	1080	4	,	,	PUNCT
fnp-3528	1080	5	32	32	NUM
fnp-3528	1080	6	,	,	PUNCT
fnp-3528	1080	7	1262	1262	NUM
fnp-3528	1080	8	-	-	SYM
fnp-3528	1080	9	72	72	NUM
fnp-3528	1080	10	.	.	PUNCT
fnp-3528	1081	1	bunay	bunay	PROPN
fnp-3528	1081	2	,	,	PUNCT
fnp-3528	1081	3	j.	j.	PROPN
fnp-3528	1081	4	;	;	PUNCT
fnp-3528	1081	5	fouache	fouache	PROPN
fnp-3528	1081	6	,	,	PUNCT
fnp-3528	1081	7	a.	a.	NOUN
fnp-3528	1081	8	;	;	PUNCT
fnp-3528	1081	9	trousson	trousson	NOUN
fnp-3528	1081	10	,	,	PUNCT
fnp-3528	1081	11	a.	a.	NOUN
fnp-3528	1081	12	;	;	PUNCT
fnp-3528	1081	13	de	de	X
fnp-3528	1081	14	joussineau	joussineau	PROPN
fnp-3528	1081	15	,	,	PUNCT
fnp-3528	1081	16	c.	c.	PROPN
fnp-3528	1081	17	;	;	PUNCT
fnp-3528	1081	18	bouchareb	bouchareb	PROPN
fnp-3528	1081	19	,	,	PUNCT
fnp-3528	1081	20	e.	e.	PROPN
fnp-3528	1081	21	;	;	PUNCT
fnp-3528	1081	22	zhu	zhu	PROPN
fnp-3528	1081	23	,	,	PUNCT
fnp-3528	1081	24	z.	z.	PROPN
fnp-3528	1081	25	;	;	PUNCT
fnp-3528	1081	26	kocer	kocer	PROPN
fnp-3528	1081	27	,	,	PUNCT
fnp-3528	1081	28	a.	a.	NOUN
fnp-3528	1081	29	;	;	PUNCT
fnp-3528	1081	30	morel	morel	PROPN
fnp-3528	1081	31	,	,	PUNCT
fnp-3528	1081	32	l.	l.	PROPN
fnp-3528	1081	33	;	;	PUNCT
fnp-3528	1081	34	baron	baron	NOUN
fnp-3528	1081	35	,	,	PUNCT
fnp-3528	1081	36	s.	s.	PROPN
fnp-3528	1081	37	;	;	PUNCT
fnp-3528	1081	38	lobaccaro	lobaccaro	PROPN
fnp-3528	1081	39	,	,	PUNCT
fnp-3528	1081	40	j.	j.	PROPN
fnp-3528	1081	41	a.	a.	PROPN
fnp-3528	1081	42	screening	screen	VERB
fnp-3528	1081	43	for	for	ADP
fnp-3528	1081	44	liver	liver	NOUN
fnp-3528	1081	45	x	x	SYM
fnp-3528	1081	46	receptor	receptor	NOUN
fnp-3528	1081	47	modulators	modulator	NOUN
fnp-3528	1081	48	:	:	PUNCT
fnp-3528	1081	49	where	where	SCONJ
fnp-3528	1081	50	are	be	AUX
fnp-3528	1081	51	we	we	PRON
fnp-3528	1081	52	and	and	CCONJ
fnp-3528	1081	53	for	for	ADP
fnp-3528	1081	54	what	what	DET
fnp-3528	1081	55	use	use	NOUN
fnp-3528	1081	56	?	?	PUNCT
fnp-3528	1082	1	br	br	PROPN
fnp-3528	1083	1	j	j	PROPN
fnp-3528	1083	2	pharmacol	pharmacol	PROPN
fnp-3528	1083	3	2020	2020	NUM
fnp-3528	1083	4	,	,	PUNCT
fnp-3528	1083	5	178	178	NUM
fnp-3528	1083	6	,	,	PUNCT
fnp-3528	1083	7	3277	3277	NUM
fnp-3528	1083	8	-	-	SYM
fnp-3528	1083	9	93	93	NUM
fnp-3528	1083	10	.	.	PUNCT
fnp-3528	1084	1	salonurmi	salonurmi	NOUN
fnp-3528	1084	2	,	,	PUNCT
fnp-3528	1084	3	t.	t.	PROPN
fnp-3528	1084	4	;	;	PUNCT
fnp-3528	1084	5	nabil	nabil	PROPN
fnp-3528	1084	6	,	,	PUNCT
fnp-3528	1084	7	h.	h.	PROPN
fnp-3528	1084	8	;	;	PUNCT
fnp-3528	1084	9	ronkainen	ronkainen	PROPN
fnp-3528	1084	10	,	,	PUNCT
fnp-3528	1084	11	j.	j.	PROPN
fnp-3528	1084	12	;	;	PUNCT
fnp-3528	1084	13	hyotylainen	hyotylainen	PROPN
fnp-3528	1084	14	,	,	PUNCT
fnp-3528	1084	15	t.	t.	PROPN
fnp-3528	1084	16	;	;	PUNCT
fnp-3528	1084	17	hautajarvi	hautajarvi	PROPN
fnp-3528	1084	18	,	,	PUNCT
fnp-3528	1084	19	h.	h.	PROPN
fnp-3528	1084	20	;	;	PUNCT
fnp-3528	1084	21	savolainen	savolainen	PROPN
fnp-3528	1084	22	,	,	PUNCT
fnp-3528	1084	23	m.	m.	NOUN
fnp-3528	1084	24	j.	j.	PROPN
fnp-3528	1084	25	;	;	PUNCT
fnp-3528	1084	26	tolonen	tolonen	PROPN
fnp-3528	1084	27	,	,	PUNCT
fnp-3528	1084	28	a.	a.	NOUN
fnp-3528	1084	29	;	;	PUNCT
fnp-3528	1084	30	oresic	oresic	ADJ
fnp-3528	1084	31	,	,	PUNCT
fnp-3528	1084	32	m.	m.	NOUN
fnp-3528	1084	33	;	;	PUNCT
fnp-3528	1084	34	kansakoski	kansakoski	PROPN
fnp-3528	1084	35	,	,	PUNCT
fnp-3528	1084	36	p.	p.	NOUN
fnp-3528	1084	37	;	;	PUNCT
fnp-3528	1084	38	rysa	rysa	NOUN
fnp-3528	1084	39	,	,	PUNCT
fnp-3528	1084	40	j.	j.	PROPN
fnp-3528	1084	41	;	;	PUNCT
fnp-3528	1084	42	hakkola	hakkola	PROPN
fnp-3528	1084	43	,	,	PUNCT
fnp-3528	1084	44	j.	j.	PROPN
fnp-3528	1084	45	;	;	PUNCT
fnp-3528	1084	46	hukkanen	hukkanen	PROPN
fnp-3528	1084	47	,	,	PUNCT
fnp-3528	1084	48	j.	j.	PROPN
fnp-3528	1084	49	4beta	4beta	PROPN
fnp-3528	1084	50	-	-	PUNCT
fnp-3528	1084	51	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	1084	52	signals	signal	NOUN
fnp-3528	1084	53	from	from	ADP
fnp-3528	1084	54	the	the	DET
fnp-3528	1084	55	liver	liver	NOUN
fnp-3528	1084	56	to	to	PART
fnp-3528	1084	57	regulate	regulate	VERB
fnp-3528	1084	58	peripheral	peripheral	ADJ
fnp-3528	1084	59	cholesterol	cholesterol	NOUN
fnp-3528	1084	60	transporters	transporter	NOUN
fnp-3528	1084	61	.	.	PUNCT
fnp-3528	1085	1	front	front	ADJ
fnp-3528	1085	2	pharmacol	pharmacol	PROPN
fnp-3528	1085	3	2020	2020	NUM
fnp-3528	1085	4	,	,	PUNCT
fnp-3528	1085	5	11	11	NUM
fnp-3528	1085	6	,	,	PUNCT
fnp-3528	1085	7	361	361	NUM
fnp-3528	1085	8	.	.	PUNCT
fnp-3528	1086	1	vaidya	vaidya	PROPN
fnp-3528	1086	2	,	,	PUNCT
fnp-3528	1086	3	m.	m.	NOUN
fnp-3528	1086	4	;	;	PUNCT
fnp-3528	1086	5	jentsch	jentsch	PROPN
fnp-3528	1086	6	,	,	PUNCT
fnp-3528	1086	7	j.	j.	PROPN
fnp-3528	1086	8	a.	a.	PROPN
fnp-3528	1086	9	;	;	PUNCT
fnp-3528	1086	10	peters	peters	PROPN
fnp-3528	1086	11	,	,	PUNCT
fnp-3528	1086	12	s.	s.	PROPN
fnp-3528	1086	13	;	;	PUNCT
fnp-3528	1086	14	keul	keul	PROPN
fnp-3528	1086	15	,	,	PUNCT
fnp-3528	1086	16	p.	p.	NOUN
fnp-3528	1086	17	;	;	PUNCT
fnp-3528	1086	18	weske	weske	PROPN
fnp-3528	1086	19	,	,	PUNCT
fnp-3528	1086	20	s.	s.	PROPN
fnp-3528	1086	21	;	;	PUNCT
fnp-3528	1086	22	graler	graler	X
fnp-3528	1086	23	,	,	PUNCT
fnp-3528	1086	24	m.	m.	NOUN
fnp-3528	1086	25	h.	h.	PROPN
fnp-3528	1086	26	;	;	PUNCT
fnp-3528	1086	27	mladenov	mladenov	PROPN
fnp-3528	1086	28	,	,	PUNCT
fnp-3528	1086	29	e.	e.	PROPN
fnp-3528	1086	30	;	;	PUNCT
fnp-3528	1086	31	iliakis	iliakis	PROPN
fnp-3528	1086	32	,	,	PUNCT
fnp-3528	1086	33	g.	g.	PROPN
fnp-3528	1086	34	;	;	PUNCT
fnp-3528	1086	35	heusch	heusch	PROPN
fnp-3528	1086	36	,	,	PUNCT
fnp-3528	1086	37	g.	g.	PROPN
fnp-3528	1086	38	;	;	PUNCT
fnp-3528	1086	39	levkau	levkau	PROPN
fnp-3528	1086	40	,	,	PUNCT
fnp-3528	1086	41	b.	b.	PROPN
fnp-3528	1086	42	regulation	regulation	NOUN
fnp-3528	1086	43	of	of	ADP
fnp-3528	1086	44	abca1	abca1	NOUN
fnp-3528	1086	45	-	-	PUNCT
fnp-3528	1086	46	mediated	mediate	VERB
fnp-3528	1086	47	cholesterol	cholesterol	NOUN
fnp-3528	1086	48	efflux	efflux	NOUN
fnp-3528	1086	49	by	by	ADP
fnp-3528	1086	50	sphingosine-1	sphingosine-1	ADV
fnp-3528	1086	51	-	-	PUNCT
fnp-3528	1086	52	phosphate	phosphate	NOUN
fnp-3528	1086	53	signaling	signal	VERB
fnp-3528	1086	54	in	in	ADP
fnp-3528	1086	55	macrophages	macrophage	NOUN
fnp-3528	1086	56	.	.	PUNCT
fnp-3528	1087	1	j	j	PROPN
fnp-3528	1087	2	lipid	lipid	PROPN
fnp-3528	1087	3	res	re	VERB
fnp-3528	1087	4	2019	2019	NUM
fnp-3528	1087	5	,	,	PUNCT
fnp-3528	1087	6	60	60	NUM
fnp-3528	1087	7	,	,	PUNCT
fnp-3528	1087	8	506	506	NUM
fnp-3528	1087	9	-	-	SYM
fnp-3528	1087	10	15	15	NUM
fnp-3528	1087	11	.	.	PUNCT
fnp-3528	1088	1	castro	castro	PROPN
fnp-3528	1088	2	navas	navas	PROPN
fnp-3528	1088	3	,	,	PUNCT
fnp-3528	1088	4	f.	f.	PROPN
fnp-3528	1088	5	f.	f.	PROPN
fnp-3528	1088	6	;	;	PUNCT
fnp-3528	1088	7	giorgi	giorgi	PROPN
fnp-3528	1088	8	,	,	PUNCT
fnp-3528	1088	9	g.	g.	PROPN
fnp-3528	1088	10	;	;	PUNCT
fnp-3528	1088	11	maggioni	maggioni	NOUN
fnp-3528	1088	12	,	,	PUNCT
fnp-3528	1088	13	d.	d.	PROPN
fnp-3528	1088	14	;	;	PUNCT
fnp-3528	1088	15	pacciarini	pacciarini	NOUN
fnp-3528	1088	16	,	,	PUNCT
fnp-3528	1088	17	m.	m.	NOUN
fnp-3528	1088	18	;	;	PUNCT
fnp-3528	1088	19	russo	russo	PROPN
fnp-3528	1088	20	,	,	PUNCT
fnp-3528	1088	21	v.	v.	PROPN
fnp-3528	1088	22	;	;	PUNCT
fnp-3528	1088	23	marinozzi	marinozzi	ADJ
fnp-3528	1088	24	,	,	PUNCT
fnp-3528	1088	25	m.	m.	NOUN
fnp-3528	1088	26	c24	c24	NOUN
fnp-3528	1088	27	-	-	PUNCT
fnp-3528	1088	28	hydroxylated	hydroxylate	VERB
fnp-3528	1088	29	stigmastane	stigmastane	NOUN
fnp-3528	1088	30	derivatives	derivative	NOUN
fnp-3528	1088	31	as	as	ADP
fnp-3528	1088	32	liver	liver	NOUN
fnp-3528	1088	33	x	x	SYM
fnp-3528	1088	34	receptor	receptor	NOUN
fnp-3528	1088	35	agonists	agonist	NOUN
fnp-3528	1088	36	.	.	PUNCT
fnp-3528	1089	1	chem	chem	NOUN
fnp-3528	1089	2	phys	phy	NOUN
fnp-3528	1089	3	lipids	lipid	VERB
fnp-3528	1089	4	2018	2018	NUM
fnp-3528	1089	5	,	,	PUNCT
fnp-3528	1089	6	212	212	NUM
fnp-3528	1089	7	,	,	PUNCT
fnp-3528	1089	8	44	44	NUM
fnp-3528	1089	9	-	-	SYM
fnp-3528	1089	10	50	50	NUM
fnp-3528	1089	11	.	.	PUNCT
fnp-3528	1090	1	hoang	hoang	PROPN
fnp-3528	1090	2	,	,	PUNCT
fnp-3528	1090	3	m.	m.	PROPN
fnp-3528	1090	4	h.	h.	PROPN
fnp-3528	1090	5	;	;	PUNCT
fnp-3528	1090	6	jia	jia	PROPN
fnp-3528	1090	7	,	,	PUNCT
fnp-3528	1090	8	y.	y.	PROPN
fnp-3528	1090	9	;	;	PUNCT
fnp-3528	1090	10	jun	jun	PROPN
fnp-3528	1090	11	,	,	PUNCT
fnp-3528	1090	12	h.	h.	PROPN
fnp-3528	1090	13	j.	j.	PROPN
fnp-3528	1090	14	;	;	PUNCT
fnp-3528	1090	15	lee	lee	PROPN
fnp-3528	1090	16	,	,	PUNCT
fnp-3528	1090	17	j.	j.	PROPN
fnp-3528	1090	18	h.	h.	PROPN
fnp-3528	1090	19	;	;	PUNCT
fnp-3528	1090	20	lee	lee	PROPN
fnp-3528	1090	21	,	,	PUNCT
fnp-3528	1090	22	b.	b.	PROPN
fnp-3528	1090	23	y.	y.	PROPN
fnp-3528	1090	24	;	;	PUNCT
fnp-3528	1090	25	lee	lee	PROPN
fnp-3528	1090	26	,	,	PUNCT
fnp-3528	1090	27	s.	s.	PROPN
fnp-3528	1090	28	j.	j.	PROPN
fnp-3528	1090	29	fucosterol	fucosterol	PROPN
fnp-3528	1090	30	is	be	AUX
fnp-3528	1090	31	a	a	DET
fnp-3528	1090	32	selective	selective	ADJ
fnp-3528	1090	33	liver	liver	NOUN
fnp-3528	1090	34	x	x	ADP
fnp-3528	1090	35	receptor	receptor	NOUN
fnp-3528	1090	36	modulator	modulator	NOUN
fnp-3528	1090	37	that	that	PRON
fnp-3528	1090	38	regulates	regulate	VERB
fnp-3528	1090	39	the	the	DET
fnp-3528	1090	40	expression	expression	NOUN
fnp-3528	1090	41	of	of	ADP
fnp-3528	1090	42	key	key	ADJ
fnp-3528	1090	43	genes	gene	NOUN
fnp-3528	1090	44	in	in	ADP
fnp-3528	1090	45	cholesterol	cholesterol	NOUN
fnp-3528	1090	46	homeostasis	homeostasis	NOUN
fnp-3528	1090	47	in	in	ADP
fnp-3528	1090	48	macrophages	macrophage	NOUN
fnp-3528	1090	49	,	,	PUNCT
fnp-3528	1090	50	hepatocytes	hepatocyte	NOUN
fnp-3528	1090	51	,	,	PUNCT
fnp-3528	1090	52	and	and	CCONJ
fnp-3528	1090	53	intestinal	intestinal	ADJ
fnp-3528	1090	54	cells	cell	NOUN
fnp-3528	1090	55	.	.	PUNCT
fnp-3528	1091	1	j	j	PROPN
fnp-3528	1091	2	agric	agric	PROPN
fnp-3528	1091	3	food	food	PROPN
fnp-3528	1091	4	chem	chem	NOUN
fnp-3528	1091	5	2012	2012	NUM
fnp-3528	1091	6	,	,	PUNCT
fnp-3528	1091	7	60	60	NUM
fnp-3528	1091	8	,	,	PUNCT
fnp-3528	1091	9	11567	11567	NUM
fnp-3528	1091	10	-	-	SYM
fnp-3528	1091	11	75	75	NUM
fnp-3528	1091	12	.	.	PUNCT
fnp-3528	1092	1	gao	gao	PROPN
fnp-3528	1092	2	,	,	PUNCT
fnp-3528	1092	3	j.	j.	PROPN
fnp-3528	1092	4	;	;	PUNCT
fnp-3528	1092	5	xu	xu	PROPN
fnp-3528	1092	6	,	,	PUNCT
fnp-3528	1092	7	y.	y.	PROPN
fnp-3528	1092	8	;	;	PUNCT
fnp-3528	1092	9	yang	yang	PROPN
fnp-3528	1092	10	,	,	PUNCT
fnp-3528	1092	11	y.	y.	PROPN
fnp-3528	1092	12	;	;	PUNCT
fnp-3528	1092	13	yang	yang	PROPN
fnp-3528	1092	14	,	,	PUNCT
fnp-3528	1092	15	y.	y.	PROPN
fnp-3528	1092	16	;	;	PUNCT
fnp-3528	1092	17	zheng	zheng	PROPN
fnp-3528	1092	18	,	,	PUNCT
fnp-3528	1092	19	z.	z.	PROPN
fnp-3528	1092	20	;	;	PUNCT
fnp-3528	1092	21	jiang	jiang	PROPN
fnp-3528	1092	22	,	,	PUNCT
fnp-3528	1092	23	w.	w.	PROPN
fnp-3528	1092	24	;	;	PUNCT
fnp-3528	1092	25	hong	hong	PROPN
fnp-3528	1092	26	,	,	PUNCT
fnp-3528	1092	27	b.	b.	PROPN
fnp-3528	1092	28	;	;	PUNCT
fnp-3528	1092	29	yan	yan	PROPN
fnp-3528	1092	30	,	,	PUNCT
fnp-3528	1092	31	x.	x.	NOUN
fnp-3528	1092	32	;	;	PUNCT
fnp-3528	1092	33	si	si	PROPN
fnp-3528	1092	34	,	,	PUNCT
fnp-3528	1092	35	s.	s.	PROPN
fnp-3528	1092	36	identification	identification	NOUN
fnp-3528	1092	37	of	of	ADP
fnp-3528	1092	38	upregulators	upregulator	NOUN
fnp-3528	1092	39	of	of	ADP
fnp-3528	1092	40	human	human	PROPN
fnp-3528	1092	41	atp	atp	PROPN
fnp-3528	1092	42	-	-	PUNCT
fnp-3528	1092	43	binding	bind	VERB
fnp-3528	1092	44	cassette	cassette	NOUN
fnp-3528	1092	45	transporter	transporter	NOUN
fnp-3528	1092	46	a1	a1	NOUN
fnp-3528	1092	47	via	via	ADP
fnp-3528	1092	48	high	high	ADJ
fnp-3528	1092	49	-	-	PUNCT
fnp-3528	1092	50	throughput	throughput	NOUN
fnp-3528	1092	51	screening	screening	NOUN
fnp-3528	1092	52	of	of	ADP
fnp-3528	1092	53	a	a	DET
fnp-3528	1092	54	synthetic	synthetic	ADJ
fnp-3528	1092	55	and	and	CCONJ
fnp-3528	1092	56	natural	natural	ADJ
fnp-3528	1092	57	compound	compound	NOUN
fnp-3528	1092	58	library	library	NOUN
fnp-3528	1092	59	.	.	PUNCT
fnp-3528	1093	1	j	j	PROPN
fnp-3528	1093	2	biomol	biomol	PROPN
fnp-3528	1093	3	screen	screen	PROPN
fnp-3528	1093	4	2008	2008	NUM
fnp-3528	1093	5	,	,	PUNCT
fnp-3528	1093	6	13	13	NUM
fnp-3528	1093	7	,	,	PUNCT
fnp-3528	1093	8	648	648	NUM
fnp-3528	1093	9	-	-	SYM
fnp-3528	1093	10	56	56	NUM
fnp-3528	1093	11	.	.	PUNCT
fnp-3528	1094	1	huang	huang	PROPN
fnp-3528	1094	2	,	,	PUNCT
fnp-3528	1094	3	t.	t.	PROPN
fnp-3528	1094	4	h.	h.	PROPN
fnp-3528	1094	5	;	;	PUNCT
fnp-3528	1094	6	razmovski	razmovski	ADJ
fnp-3528	1094	7	-	-	PUNCT
fnp-3528	1094	8	naumovski	naumovski	ADJ
fnp-3528	1094	9	,	,	PUNCT
fnp-3528	1094	10	v.	v.	PROPN
fnp-3528	1094	11	;	;	PUNCT
fnp-3528	1094	12	salam	salam	PROPN
fnp-3528	1094	13	,	,	PUNCT
fnp-3528	1094	14	n.	n.	PROPN
fnp-3528	1094	15	k.	k.	PROPN
fnp-3528	1094	16	;	;	PUNCT
fnp-3528	1094	17	duke	duke	PROPN
fnp-3528	1094	18	,	,	PUNCT
fnp-3528	1094	19	r.	r.	PROPN
fnp-3528	1094	20	k.	k.	PROPN
fnp-3528	1094	21	;	;	PUNCT
fnp-3528	1094	22	tran	tran	PROPN
fnp-3528	1094	23	,	,	PUNCT
fnp-3528	1094	24	v.	v.	PROPN
fnp-3528	1094	25	h.	h.	PROPN
fnp-3528	1094	26	;	;	PUNCT
fnp-3528	1094	27	duke	duke	PROPN
fnp-3528	1094	28	,	,	PUNCT
fnp-3528	1094	29	c.	c.	PROPN
fnp-3528	1094	30	c.	c.	PROPN
fnp-3528	1094	31	;	;	PUNCT
fnp-3528	1094	32	roufogalis	roufogalis	PROPN
fnp-3528	1094	33	,	,	PUNCT
fnp-3528	1094	34	b.	b.	PROPN
fnp-3528	1094	35	d.	d.	PROPN
fnp-3528	1094	36	a	a	DET
fnp-3528	1094	37	novel	novel	ADJ
fnp-3528	1094	38	lxr	lxr	NOUN
fnp-3528	1094	39	-	-	PUNCT
fnp-3528	1094	40	alpha	alpha	NOUN
fnp-3528	1094	41	activator	activator	NOUN
fnp-3528	1094	42	identified	identify	VERB
fnp-3528	1094	43	from	from	ADP
fnp-3528	1094	44	the	the	DET
fnp-3528	1094	45	natural	natural	ADJ
fnp-3528	1094	46	product	product	NOUN
fnp-3528	1094	47	gynostemma	gynostemma	PROPN
fnp-3528	1094	48	pentaphyllum	pentaphyllum	PROPN
fnp-3528	1094	49	.	.	PUNCT
fnp-3528	1095	1	biochem	biochem	PROPN
fnp-3528	1095	2	pharmacol	pharmacol	PROPN
fnp-3528	1095	3	2005	2005	NUM
fnp-3528	1095	4	,	,	PUNCT
fnp-3528	1095	5	70	70	NUM
fnp-3528	1095	6	,	,	PUNCT
fnp-3528	1095	7	1298	1298	NUM
fnp-3528	1095	8	-	-	SYM
fnp-3528	1095	9	308	308	NUM
fnp-3528	1095	10	.	.	PUNCT
fnp-3528	1096	1	agassandian	agassandian	ADJ
fnp-3528	1096	2	,	,	PUNCT
fnp-3528	1096	3	m.	m.	NOUN
fnp-3528	1096	4	;	;	PUNCT
fnp-3528	1096	5	mathur	mathur	PROPN
fnp-3528	1096	6	,	,	PUNCT
fnp-3528	1096	7	s.	s.	PROPN
fnp-3528	1096	8	n.	n.	PROPN
fnp-3528	1096	9	;	;	PUNCT
fnp-3528	1097	1	zhou	zhou	PROPN
fnp-3528	1097	2	,	,	PUNCT
fnp-3528	1097	3	j.	j.	PROPN
fnp-3528	1097	4	;	;	PUNCT
fnp-3528	1097	5	field	field	PROPN
fnp-3528	1097	6	,	,	PUNCT
fnp-3528	1097	7	f.	f.	PROPN
fnp-3528	1097	8	j.	j.	PROPN
fnp-3528	1097	9	;	;	PUNCT
fnp-3528	1097	10	mallampalli	mallampalli	PROPN
fnp-3528	1097	11	,	,	PUNCT
fnp-3528	1097	12	r.	r.	PROPN
fnp-3528	1097	13	k.	k.	PROPN
fnp-3528	1097	14	oxysterols	oxysterols	PROPN
fnp-3528	1097	15	trigger	trigger	NOUN
fnp-3528	1097	16	abca1	abca1	NOUN
fnp-3528	1097	17	-	-	PUNCT
fnp-3528	1097	18	mediated	mediate	VERB
fnp-3528	1097	19	basolateral	basolateral	ADJ
fnp-3528	1097	20	surfactant	surfactant	NOUN
fnp-3528	1097	21	efflux	efflux	NOUN
fnp-3528	1097	22	.	.	PUNCT
fnp-3528	1098	1	am	be	AUX
fnp-3528	1098	2	j	j	PROPN
fnp-3528	1098	3	respir	respir	NOUN
fnp-3528	1098	4	cell	cell	NOUN
fnp-3528	1098	5	mol	mol	ADP
fnp-3528	1098	6	biol	biol	PROPN
fnp-3528	1098	7	2004	2004	NUM
fnp-3528	1098	8	,	,	PUNCT
fnp-3528	1098	9	31	31	NUM
fnp-3528	1098	10	,	,	PUNCT
fnp-3528	1098	11	227	227	NUM
fnp-3528	1098	12	-	-	SYM
fnp-3528	1098	13	33	33	NUM
fnp-3528	1098	14	.	.	PUNCT
fnp-3528	1099	1	sone	sone	PROPN
fnp-3528	1099	2	,	,	PUNCT
fnp-3528	1099	3	h.	h.	PROPN
fnp-3528	1099	4	;	;	PUNCT
fnp-3528	1099	5	shimano	shimano	PROPN
fnp-3528	1099	6	,	,	PUNCT
fnp-3528	1099	7	h.	h.	PROPN
fnp-3528	1099	8	;	;	PUNCT
fnp-3528	1099	9	shu	shu	PROPN
fnp-3528	1099	10	,	,	PUNCT
fnp-3528	1099	11	m.	m.	NOUN
fnp-3528	1099	12	;	;	PUNCT
fnp-3528	1099	13	nakakuki	nakakuki	ADJ
fnp-3528	1099	14	,	,	PUNCT
fnp-3528	1099	15	m.	m.	NOUN
fnp-3528	1099	16	;	;	PUNCT
fnp-3528	1099	17	takahashi	takahashi	PROPN
fnp-3528	1099	18	,	,	PUNCT
fnp-3528	1099	19	a.	a.	NOUN
fnp-3528	1099	20	;	;	PUNCT
fnp-3528	1099	21	sakai	sakai	NOUN
fnp-3528	1099	22	,	,	PUNCT
fnp-3528	1099	23	m.	m.	NOUN
fnp-3528	1099	24	;	;	PUNCT
fnp-3528	1099	25	sakamoto	sakamoto	NOUN
fnp-3528	1099	26	,	,	PUNCT
fnp-3528	1099	27	y.	y.	PROPN
fnp-3528	1099	28	;	;	PUNCT
fnp-3528	1099	29	yokoo	yokoo	PROPN
fnp-3528	1099	30	,	,	PUNCT
fnp-3528	1099	31	t.	t.	PROPN
fnp-3528	1099	32	;	;	PUNCT
fnp-3528	1099	33	matsuzaka	matsuzaka	PROPN
fnp-3528	1099	34	,	,	PUNCT
fnp-3528	1099	35	k.	k.	PROPN
fnp-3528	1099	36	;	;	PUNCT
fnp-3528	1099	37	okazaki	okazaki	PROPN
fnp-3528	1099	38	,	,	PUNCT
fnp-3528	1099	39	h.	h.	PROPN
fnp-3528	1099	40	;	;	PUNCT
fnp-3528	1099	41	nakagawa	nakagawa	PROPN
fnp-3528	1099	42	,	,	PUNCT
fnp-3528	1099	43	y.	y.	PROPN
fnp-3528	1099	44	;	;	PUNCT
fnp-3528	1099	45	iida	iida	PROPN
fnp-3528	1099	46	,	,	PUNCT
fnp-3528	1099	47	k.	k.	PROPN
fnp-3528	1099	48	t.	t.	PROPN
fnp-3528	1099	49	;	;	PUNCT
fnp-3528	1099	50	suzuki	suzuki	PROPN
fnp-3528	1099	51	,	,	PUNCT
fnp-3528	1099	52	h.	h.	PROPN
fnp-3528	1099	53	;	;	PUNCT
fnp-3528	1099	54	toyoshima	toyoshima	PROPN
fnp-3528	1099	55	,	,	PUNCT
fnp-3528	1099	56	h.	h.	PROPN
fnp-3528	1099	57	;	;	PUNCT
fnp-3528	1099	58	horiuchi	horiuchi	PROPN
fnp-3528	1099	59	,	,	PUNCT
fnp-3528	1099	60	s.	s.	PROPN
fnp-3528	1099	61	;	;	PUNCT
fnp-3528	1099	62	yamada	yamada	PROPN
fnp-3528	1099	63	,	,	PUNCT
fnp-3528	1099	64	n.	n.	PROPN
fnp-3528	1099	65	statins	statins	PROPN
fnp-3528	1099	66	downregulate	downregulate	PROPN
fnp-3528	1099	67	atp	atp	PROPN
fnp-3528	1099	68	-	-	PUNCT
fnp-3528	1099	69	binding	binding	ADJ
fnp-3528	1099	70	-	-	PUNCT
fnp-3528	1099	71	cassette	cassette	NOUN
fnp-3528	1099	72	transporter	transporter	NOUN
fnp-3528	1099	73	a1	a1	NOUN
fnp-3528	1099	74	gene	gene	NOUN
fnp-3528	1099	75	expression	expression	NOUN
fnp-3528	1099	76	in	in	ADP
fnp-3528	1099	77	macrophages	macrophage	NOUN
fnp-3528	1099	78	.	.	PUNCT
fnp-3528	1100	1	biochem	biochem	PROPN
fnp-3528	1100	2	biophys	biophys	PROPN
fnp-3528	1100	3	res	res	PROPN
fnp-3528	1100	4	commun	commun	PROPN
fnp-3528	1100	5	2004	2004	NUM
fnp-3528	1100	6	,	,	PUNCT
fnp-3528	1100	7	316	316	NUM
fnp-3528	1100	8	,	,	PUNCT
fnp-3528	1100	9	790	790	NUM
fnp-3528	1100	10	-	-	SYM
fnp-3528	1100	11	4	4	NUM
fnp-3528	1100	12	.	.	X
fnp-3528	1101	1	zhang	zhang	PROPN
fnp-3528	1101	2	,	,	PUNCT
fnp-3528	1101	3	y.	y.	PROPN
fnp-3528	1101	4	;	;	PUNCT
fnp-3528	1101	5	beyer	beyer	PROPN
fnp-3528	1101	6	,	,	PUNCT
fnp-3528	1101	7	t.	t.	PROPN
fnp-3528	1101	8	p.	p.	PROPN
fnp-3528	1101	9	;	;	PUNCT
fnp-3528	1101	10	bramlett	bramlett	PROPN
fnp-3528	1101	11	,	,	PUNCT
fnp-3528	1101	12	k.	k.	PROPN
fnp-3528	1101	13	s.	s.	PROPN
fnp-3528	1101	14	;	;	PUNCT
fnp-3528	1101	15	yao	yao	PROPN
fnp-3528	1101	16	,	,	PUNCT
fnp-3528	1101	17	s.	s.	PROPN
fnp-3528	1101	18	;	;	PUNCT
fnp-3528	1101	19	burris	burris	PROPN
fnp-3528	1101	20	,	,	PUNCT
fnp-3528	1101	21	t.	t.	PROPN
fnp-3528	1101	22	p.	p.	PROPN
fnp-3528	1101	23	;	;	PUNCT
fnp-3528	1101	24	schmidt	schmidt	PROPN
fnp-3528	1101	25	,	,	PUNCT
fnp-3528	1101	26	r.	r.	PROPN
fnp-3528	1101	27	j.	j.	PROPN
fnp-3528	1101	28	;	;	PUNCT
fnp-3528	1101	29	eacho	eacho	PROPN
fnp-3528	1101	30	,	,	PUNCT
fnp-3528	1101	31	p.	p.	NOUN
fnp-3528	1101	32	i.	i.	PROPN
fnp-3528	1101	33	;	;	PUNCT
fnp-3528	1101	34	cao	cao	PROPN
fnp-3528	1101	35	,	,	PUNCT
fnp-3528	1101	36	g.	g.	PROPN
fnp-3528	1101	37	liver	liver	NOUN
fnp-3528	1101	38	x	x	SYM
fnp-3528	1101	39	receptor	receptor	NOUN
fnp-3528	1101	40	and	and	CCONJ
fnp-3528	1101	41	retinoic	retinoic	ADJ
fnp-3528	1101	42	x	x	SYM
fnp-3528	1101	43	receptor	receptor	NOUN
fnp-3528	1101	44	mediated	mediate	VERB
fnp-3528	1101	45	abca1	abca1	NOUN
fnp-3528	1101	46	regulation	regulation	NOUN
fnp-3528	1101	47	and	and	CCONJ
fnp-3528	1101	48	cholesterol	cholesterol	NOUN
fnp-3528	1101	49	efflux	efflux	VERB
fnp-3528	1101	50	in	in	ADP
fnp-3528	1101	51	macrophage	macrophage	ADJ
fnp-3528	1101	52	cells	cell	NOUN
fnp-3528	1101	53	-	-	PUNCT
fnp-3528	1101	54	messenger	messenger	NOUN
fnp-3528	1101	55	rna	rna	NOUN
fnp-3528	1101	56	measured	measure	VERB
fnp-3528	1101	57	by	by	ADP
fnp-3528	1101	58	branched	branched	ADJ
fnp-3528	1101	59	dna	dna	PROPN
fnp-3528	1101	60	technology	technology	NOUN
fnp-3528	1101	61	.	.	PUNCT
fnp-3528	1102	1	mol	mol	ADP
fnp-3528	1102	2	genet	genet	PROPN
fnp-3528	1102	3	metab	metab	PROPN
fnp-3528	1102	4	2002	2002	NUM
fnp-3528	1102	5	,	,	PUNCT
fnp-3528	1102	6	77	77	NUM
fnp-3528	1102	7	,	,	PUNCT
fnp-3528	1102	8	150	150	NUM
fnp-3528	1102	9	-	-	SYM
fnp-3528	1102	10	8	8	NUM
fnp-3528	1102	11	.	.	PUNCT
fnp-3528	1102	12	gan	gan	PROPN
fnp-3528	1102	13	,	,	PUNCT
fnp-3528	1102	14	x.	x.	PROPN
fnp-3528	1102	15	;	;	PUNCT
fnp-3528	1102	16	kaplan	kaplan	PROPN
fnp-3528	1102	17	,	,	PUNCT
fnp-3528	1102	18	r.	r.	PROPN
fnp-3528	1102	19	;	;	PUNCT
fnp-3528	1102	20	menke	menke	NOUN
fnp-3528	1102	21	,	,	PUNCT
fnp-3528	1102	22	j.	j.	PROPN
fnp-3528	1102	23	g.	g.	PROPN
fnp-3528	1102	24	;	;	PUNCT
fnp-3528	1102	25	macnaul	macnaul	PROPN
fnp-3528	1102	26	,	,	PUNCT
fnp-3528	1102	27	k.	k.	PROPN
fnp-3528	1102	28	;	;	PUNCT
fnp-3528	1102	29	chen	chen	PROPN
fnp-3528	1102	30	,	,	PUNCT
fnp-3528	1102	31	y.	y.	PROPN
fnp-3528	1102	32	;	;	PUNCT
fnp-3528	1102	33	sparrow	sparrow	NOUN
fnp-3528	1102	34	,	,	PUNCT
fnp-3528	1102	35	c.	c.	PROPN
fnp-3528	1102	36	p.	p.	PROPN
fnp-3528	1102	37	;	;	PUNCT
fnp-3528	1103	1	zhou	zhou	PROPN
fnp-3528	1103	2	,	,	PUNCT
fnp-3528	1103	3	g.	g.	PROPN
fnp-3528	1103	4	;	;	PUNCT
fnp-3528	1103	5	wright	wright	PROPN
fnp-3528	1103	6	,	,	PUNCT
fnp-3528	1103	7	s.	s.	PROPN
fnp-3528	1103	8	d.	d.	PROPN
fnp-3528	1103	9	;	;	PUNCT
fnp-3528	1103	10	cai	cai	X
fnp-3528	1103	11	,	,	PUNCT
fnp-3528	1103	12	t.	t.	PROPN
fnp-3528	1103	13	q.	q.	PROPN
fnp-3528	1103	14	dual	dual	ADJ
fnp-3528	1103	15	mechanisms	mechanism	NOUN
fnp-3528	1103	16	of	of	ADP
fnp-3528	1103	17	abca1	abca1	NOUN
fnp-3528	1103	18	regulation	regulation	NOUN
fnp-3528	1103	19	by	by	ADP
fnp-3528	1103	20	geranylgeranyl	geranylgeranyl	ADJ
fnp-3528	1103	21	pyrophosphate	pyrophosphate	NOUN
fnp-3528	1103	22	.	.	PUNCT
fnp-3528	1104	1	j	j	PROPN
fnp-3528	1104	2	biol	biol	PROPN
fnp-3528	1104	3	chem	chem	NOUN
fnp-3528	1104	4	2001	2001	NUM
fnp-3528	1104	5	,	,	PUNCT
fnp-3528	1104	6	276	276	NUM
fnp-3528	1104	7	,	,	PUNCT
fnp-3528	1104	8	48702	48702	NUM
fnp-3528	1104	9	-	-	SYM
fnp-3528	1104	10	8	8	NUM
fnp-3528	1104	11	.	.	PUNCT
fnp-3528	1105	1	chawla	chawla	PROPN
fnp-3528	1105	2	,	,	PUNCT
fnp-3528	1105	3	a.	a.	PROPN
fnp-3528	1105	4	;	;	PUNCT
fnp-3528	1105	5	boisvert	boisvert	PROPN
fnp-3528	1105	6	,	,	PUNCT
fnp-3528	1105	7	w.	w.	PROPN
fnp-3528	1105	8	a.	a.	PROPN
fnp-3528	1105	9	;	;	PUNCT
fnp-3528	1105	10	lee	lee	PROPN
fnp-3528	1105	11	,	,	PUNCT
fnp-3528	1105	12	c.	c.	PROPN
fnp-3528	1105	13	h.	h.	PROPN
fnp-3528	1105	14	;	;	PUNCT
fnp-3528	1105	15	laffitte	laffitte	PROPN
fnp-3528	1105	16	,	,	PUNCT
fnp-3528	1105	17	b.	b.	PROPN
fnp-3528	1105	18	a.	a.	PROPN
fnp-3528	1105	19	;	;	PUNCT
fnp-3528	1105	20	barak	barak	PROPN
fnp-3528	1105	21	,	,	PUNCT
fnp-3528	1105	22	y.	y.	PROPN
fnp-3528	1105	23	;	;	PUNCT
fnp-3528	1105	24	joseph	joseph	PROPN
fnp-3528	1105	25	,	,	PUNCT
fnp-3528	1105	26	s.	s.	PROPN
fnp-3528	1105	27	b.	b.	PROPN
fnp-3528	1105	28	;	;	PUNCT
fnp-3528	1105	29	liao	liao	PROPN
fnp-3528	1105	30	,	,	PUNCT
fnp-3528	1105	31	d.	d.	PROPN
fnp-3528	1105	32	;	;	PUNCT
fnp-3528	1105	33	nagy	nagy	PROPN
fnp-3528	1105	34	,	,	PUNCT
fnp-3528	1105	35	l.	l.	PROPN
fnp-3528	1105	36	;	;	PUNCT
fnp-3528	1105	37	edwards	edwards	PROPN
fnp-3528	1105	38	,	,	PUNCT
fnp-3528	1105	39	p.	p.	NOUN
fnp-3528	1105	40	a.	a.	NOUN
fnp-3528	1105	41	;	;	PUNCT
fnp-3528	1105	42	curtiss	curtiss	PROPN
fnp-3528	1105	43	,	,	PUNCT
fnp-3528	1105	44	l.	l.	PROPN
fnp-3528	1105	45	k.	k.	PROPN
fnp-3528	1105	46	;	;	PUNCT
fnp-3528	1105	47	evans	evans	PROPN
fnp-3528	1105	48	,	,	PUNCT
fnp-3528	1105	49	r.	r.	PROPN
fnp-3528	1105	50	m.	m.	PROPN
fnp-3528	1105	51	;	;	PUNCT
fnp-3528	1105	52	tontonoz	tontonoz	PROPN
fnp-3528	1105	53	,	,	PUNCT
fnp-3528	1105	54	p.	p.	NOUN
fnp-3528	1105	55	a	a	DET
fnp-3528	1105	56	ppar	ppar	NOUN
fnp-3528	1105	57	gamma	gamma	NOUN
fnp-3528	1105	58	-	-	PUNCT
fnp-3528	1105	59	lxr	lxr	NOUN
fnp-3528	1105	60	-	-	PUNCT
fnp-3528	1105	61	abca1	abca1	NOUN
fnp-3528	1105	62	pathway	pathway	NOUN
fnp-3528	1105	63	in	in	ADP
fnp-3528	1105	64	macrophages	macrophage	NOUN
fnp-3528	1105	65	is	be	AUX
fnp-3528	1105	66	involved	involve	VERB
fnp-3528	1105	67	in	in	ADP
fnp-3528	1105	68	cholesterol	cholesterol	NOUN
fnp-3528	1105	69	efflux	efflux	NOUN
fnp-3528	1105	70	and	and	CCONJ
fnp-3528	1105	71	atherogenesis	atherogenesis	NOUN
fnp-3528	1105	72	.	.	PUNCT
fnp-3528	1106	1	mol	mol	ADP
fnp-3528	1106	2	cell	cell	NOUN
fnp-3528	1106	3	2001	2001	NUM
fnp-3528	1106	4	,	,	PUNCT
fnp-3528	1106	5	7	7	NUM
fnp-3528	1106	6	,	,	PUNCT
fnp-3528	1106	7	161	161	NUM
fnp-3528	1106	8	-	-	SYM
fnp-3528	1106	9	71	71	NUM
fnp-3528	1106	10	.	.	PUNCT
fnp-3528	1107	1	arakawa	arakawa	PROPN
fnp-3528	1107	2	,	,	PUNCT
fnp-3528	1107	3	r.	r.	PROPN
fnp-3528	1107	4	;	;	PUNCT
fnp-3528	1107	5	yokoyama	yokoyama	PROPN
fnp-3528	1107	6	,	,	PUNCT
fnp-3528	1107	7	s.	s.	PROPN
fnp-3528	1107	8	helical	helical	PROPN
fnp-3528	1107	9	apolipoproteins	apolipoprotein	NOUN
fnp-3528	1107	10	stabilize	stabilize	VERB
fnp-3528	1107	11	atp	atp	NOUN
fnp-3528	1107	12	-	-	PUNCT
fnp-3528	1107	13	binding	bind	VERB
fnp-3528	1107	14	cassette	cassette	NOUN
fnp-3528	1107	15	transporter	transporter	NOUN
fnp-3528	1107	16	a1	a1	NOUN
fnp-3528	1107	17	by	by	ADP
fnp-3528	1107	18	protecting	protect	VERB
fnp-3528	1107	19	it	it	PRON
fnp-3528	1107	20	from	from	ADP
fnp-3528	1107	21	thiol	thiol	ADJ
fnp-3528	1107	22	protease	protease	NOUN
fnp-3528	1107	23	-	-	PUNCT
fnp-3528	1107	24	mediated	mediate	VERB
fnp-3528	1107	25	degradation	degradation	NOUN
fnp-3528	1107	26	.	.	PUNCT
fnp-3528	1108	1	j	j	PROPN
fnp-3528	1108	2	biol	biol	PROPN
fnp-3528	1108	3	chem	chem	NOUN
fnp-3528	1108	4	2002	2002	NUM
fnp-3528	1108	5	,	,	PUNCT
fnp-3528	1108	6	277	277	NUM
fnp-3528	1108	7	,	,	PUNCT
fnp-3528	1108	8	22426	22426	NUM
fnp-3528	1108	9	-	-	SYM
fnp-3528	1108	10	9	9	NUM
fnp-3528	1108	11	.	.	X
fnp-3528	1108	12	di	di	PROPN
fnp-3528	1108	13	,	,	PUNCT
fnp-3528	1108	14	d.	d.	PROPN
fnp-3528	1108	15	;	;	PUNCT
fnp-3528	1108	16	wang	wang	PROPN
fnp-3528	1108	17	,	,	PUNCT
fnp-3528	1108	18	z.	z.	PROPN
fnp-3528	1108	19	;	;	PUNCT
fnp-3528	1108	20	liu	liu	PROPN
fnp-3528	1108	21	,	,	PUNCT
fnp-3528	1108	22	y.	y.	PROPN
fnp-3528	1108	23	;	;	PUNCT
fnp-3528	1108	24	luo	luo	PROPN
fnp-3528	1108	25	,	,	PUNCT
fnp-3528	1108	26	g.	g.	PROPN
fnp-3528	1108	27	;	;	PUNCT
fnp-3528	1108	28	shi	shi	PROPN
fnp-3528	1108	29	,	,	PUNCT
fnp-3528	1108	30	y.	y.	PROPN
fnp-3528	1108	31	;	;	PUNCT
fnp-3528	1108	32	berggren	berggren	PROPN
fnp-3528	1108	33	-	-	PUNCT
fnp-3528	1108	34	soderlund	soderlund	PROPN
fnp-3528	1108	35	,	,	PUNCT
fnp-3528	1108	36	m.	m.	NOUN
fnp-3528	1108	37	;	;	PUNCT
fnp-3528	1108	38	nilsson	nilsson	PROPN
fnp-3528	1108	39	-	-	PUNCT
fnp-3528	1108	40	ehle	ehle	PROPN
fnp-3528	1108	41	,	,	PUNCT
fnp-3528	1108	42	p.	p.	PROPN
fnp-3528	1108	43	;	;	PUNCT
fnp-3528	1108	44	zhang	zhang	PROPN
fnp-3528	1108	45	,	,	PUNCT
fnp-3528	1108	46	x.	x.	PROPN
fnp-3528	1108	47	;	;	PUNCT
fnp-3528	1108	48	xu	xu	PROPN
fnp-3528	1108	49	,	,	PUNCT
fnp-3528	1108	50	n.	n.	PROPN
fnp-3528	1108	51	abca1	abca1	PROPN
fnp-3528	1108	52	upregulating	upregulating	PROPN
fnp-3528	1108	53	apolipoproein	apolipoproein	NOUN
fnp-3528	1108	54	m	m	PROPN
fnp-3528	1108	55	expression	expression	NOUN
fnp-3528	1108	56	mediates	mediate	NOUN
fnp-3528	1108	57	via	via	ADP
fnp-3528	1108	58	the	the	DET
fnp-3528	1108	59	rxr	rxr	PROPN
fnp-3528	1108	60	/	/	SYM
fnp-3528	1108	61	lxr	lxr	PROPN
fnp-3528	1108	62	pathway	pathway	NOUN
fnp-3528	1108	63	in	in	ADP
fnp-3528	1108	64	hepg2	hepg2	NOUN
fnp-3528	1108	65	cells	cell	NOUN
fnp-3528	1108	66	.	.	PUNCT
fnp-3528	1109	1	biochem	biochem	PROPN
fnp-3528	1109	2	biophys	biophys	PROPN
fnp-3528	1109	3	res	res	PROPN
fnp-3528	1109	4	commun	commun	PROPN
fnp-3528	1109	5	2012	2012	NUM
fnp-3528	1109	6	,	,	PUNCT
fnp-3528	1109	7	421	421	NUM
fnp-3528	1109	8	,	,	PUNCT
fnp-3528	1109	9	152	152	NUM
fnp-3528	1109	10	-	-	SYM
fnp-3528	1109	11	6	6	NUM
fnp-3528	1109	12	.	.	PUNCT
fnp-3528	1109	13	zanotti	zanotti	PROPN
fnp-3528	1109	14	,	,	PUNCT
fnp-3528	1109	15	i.	i.	NOUN
fnp-3528	1109	16	;	;	PUNCT
fnp-3528	1109	17	favari	favari	PROPN
fnp-3528	1109	18	,	,	PUNCT
fnp-3528	1109	19	e.	e.	PROPN
fnp-3528	1109	20	;	;	PUNCT
fnp-3528	1109	21	sposito	sposito	PROPN
fnp-3528	1109	22	,	,	PUNCT
fnp-3528	1109	23	a.	a.	PROPN
fnp-3528	1109	24	c.	c.	PROPN
fnp-3528	1109	25	;	;	PUNCT
fnp-3528	1109	26	rothblat	rothblat	NOUN
fnp-3528	1109	27	,	,	PUNCT
fnp-3528	1109	28	g.	g.	PROPN
fnp-3528	1109	29	h.	h.	PROPN
fnp-3528	1109	30	;	;	PUNCT
fnp-3528	1109	31	bernini	bernini	PROPN
fnp-3528	1109	32	,	,	PUNCT
fnp-3528	1109	33	f.	f.	PROPN
fnp-3528	1109	34	pitavastatin	pitavastatin	PROPN
fnp-3528	1109	35	increases	increase	VERB
fnp-3528	1109	36	abca1	abca1	NOUN
fnp-3528	1109	37	-	-	PUNCT
fnp-3528	1109	38	mediated	mediate	VERB
fnp-3528	1109	39	lipid	lipid	NOUN
fnp-3528	1109	40	efflux	efflux	VERB
fnp-3528	1109	41	from	from	ADP
fnp-3528	1109	42	fu5ah	fu5ah	VERB
fnp-3528	1109	43	rat	rat	NOUN
fnp-3528	1109	44	hepatoma	hepatoma	ADJ
fnp-3528	1109	45	cells	cell	NOUN
fnp-3528	1109	46	.	.	PUNCT
fnp-3528	1110	1	biochem	biochem	PROPN
fnp-3528	1110	2	biophys	biophys	PROPN
fnp-3528	1110	3	res	res	PROPN
fnp-3528	1110	4	commun	commun	PROPN
fnp-3528	1110	5	2004	2004	NUM
fnp-3528	1110	6	,	,	PUNCT
fnp-3528	1110	7	321	321	NUM
fnp-3528	1110	8	,	,	PUNCT
fnp-3528	1110	9	670	670	NUM
fnp-3528	1110	10	-	-	SYM
fnp-3528	1110	11	4	4	NUM
fnp-3528	1110	12	.	.	PUNCT
fnp-3528	1110	13	ben	ben	PROPN
fnp-3528	1110	14	aissa	aissa	PROPN
fnp-3528	1110	15	,	,	PUNCT
fnp-3528	1110	16	m.	m.	NOUN
fnp-3528	1110	17	;	;	PUNCT
fnp-3528	1110	18	lewandowski	lewandowski	PROPN
fnp-3528	1110	19	,	,	PUNCT
fnp-3528	1110	20	c.	c.	PROPN
fnp-3528	1110	21	t.	t.	PROPN
fnp-3528	1110	22	;	;	PUNCT
fnp-3528	1110	23	ratia	ratia	PROPN
fnp-3528	1110	24	,	,	PUNCT
fnp-3528	1110	25	k.	k.	PROPN
fnp-3528	1110	26	m.	m.	PROPN
fnp-3528	1110	27	;	;	PUNCT
fnp-3528	1110	28	lee	lee	PROPN
fnp-3528	1110	29	,	,	PUNCT
fnp-3528	1110	30	s.	s.	PROPN
fnp-3528	1110	31	h.	h.	PROPN
fnp-3528	1110	32	;	;	PUNCT
fnp-3528	1110	33	layden	layden	PROPN
fnp-3528	1110	34	,	,	PUNCT
fnp-3528	1110	35	b.	b.	PROPN
fnp-3528	1110	36	t.	t.	PROPN
fnp-3528	1110	37	;	;	PUNCT
fnp-3528	1110	38	ladu	ladu	ADJ
fnp-3528	1110	39	,	,	PUNCT
fnp-3528	1110	40	m.	m.	NOUN
fnp-3528	1110	41	j.	j.	PROPN
fnp-3528	1110	42	;	;	PUNCT
fnp-3528	1110	43	thatcher	thatcher	PROPN
fnp-3528	1110	44	,	,	PUNCT
fnp-3528	1110	45	g.	g.	PROPN
fnp-3528	1110	46	r.	r.	PROPN
fnp-3528	1110	47	j.	j.	PROPN
fnp-3528	1110	48	discovery	discovery	PROPN
fnp-3528	1110	49	of	of	ADP
fnp-3528	1110	50	nonlipogenic	nonlipogenic	ADJ
fnp-3528	1110	51	abca1	abca1	NOUN
fnp-3528	1110	52	inducing	induce	VERB
fnp-3528	1110	53	compounds	compound	NOUN
fnp-3528	1110	54	with	with	ADP
fnp-3528	1110	55	potential	potential	NOUN
fnp-3528	1110	56	in	in	ADP
fnp-3528	1110	57	alzheimer	alzheimer	PROPN
fnp-3528	1110	58	's	's	PART
fnp-3528	1110	59	disease	disease	NOUN
fnp-3528	1110	60	and	and	CCONJ
fnp-3528	1110	61	type	type	NOUN
fnp-3528	1110	62	2	2	NUM
fnp-3528	1110	63	diabetes	diabetes	NOUN
fnp-3528	1110	64	.	.	PUNCT
fnp-3528	1111	1	acs	acs	PROPN
fnp-3528	1111	2	pharmacol	pharmacol	PROPN
fnp-3528	1111	3	transl	transl	PROPN
fnp-3528	1111	4	sci	sci	PROPN
fnp-3528	1111	5	2021	2021	NUM
fnp-3528	1111	6	,	,	PUNCT
fnp-3528	1111	7	4	4	NUM
fnp-3528	1111	8	,	,	PUNCT
fnp-3528	1111	9	143	143	NUM
fnp-3528	1111	10	-	-	SYM
fnp-3528	1111	11	54	54	NUM
fnp-3528	1111	12	.	.	PUNCT
fnp-3528	1112	1	ma	ma	PROPN
fnp-3528	1112	2	,	,	PUNCT
fnp-3528	1112	3	l.	l.	PROPN
fnp-3528	1112	4	;	;	PUNCT
fnp-3528	1112	5	wang	wang	PROPN
fnp-3528	1112	6	,	,	PUNCT
fnp-3528	1112	7	l.	l.	PROPN
fnp-3528	1112	8	;	;	PUNCT
fnp-3528	1112	9	nelson	nelson	PROPN
fnp-3528	1112	10	,	,	PUNCT
fnp-3528	1112	11	a.	a.	NOUN
fnp-3528	1112	12	t.	t.	PROPN
fnp-3528	1112	13	;	;	PUNCT
fnp-3528	1112	14	han	han	PROPN
fnp-3528	1112	15	,	,	PUNCT
fnp-3528	1112	16	c.	c.	PROPN
fnp-3528	1112	17	;	;	PUNCT
fnp-3528	1112	18	he	he	PRON
fnp-3528	1112	19	,	,	PUNCT
fnp-3528	1112	20	s.	s.	PROPN
fnp-3528	1112	21	;	;	PUNCT
fnp-3528	1112	22	henn	henn	PROPN
fnp-3528	1112	23	,	,	PUNCT
fnp-3528	1112	24	m.	m.	NOUN
fnp-3528	1112	25	a.	a.	PROPN
fnp-3528	1112	26	;	;	PUNCT
fnp-3528	1112	27	menon	menon	PROPN
fnp-3528	1112	28	,	,	PUNCT
fnp-3528	1112	29	k.	k.	PROPN
fnp-3528	1112	30	;	;	PUNCT
fnp-3528	1112	31	chen	chen	PROPN
fnp-3528	1112	32	,	,	PUNCT
fnp-3528	1112	33	j.	j.	PROPN
fnp-3528	1112	34	j.	j.	PROPN
fnp-3528	1112	35	;	;	PUNCT
fnp-3528	1112	36	baek	baek	PROPN
fnp-3528	1112	37	,	,	PUNCT
fnp-3528	1112	38	a.	a.	PROPN
fnp-3528	1112	39	e.	e.	PROPN
fnp-3528	1112	40	;	;	PUNCT
fnp-3528	1112	41	vardanyan	vardanyan	ADJ
fnp-3528	1112	42	,	,	PUNCT
fnp-3528	1112	43	a.	a.	NOUN
fnp-3528	1112	44	;	;	PUNCT
fnp-3528	1112	45	shahoei	shahoei	PROPN
fnp-3528	1112	46	,	,	PUNCT
fnp-3528	1112	47	s.	s.	PROPN
fnp-3528	1112	48	h.	h.	PROPN
fnp-3528	1112	49	;	;	PUNCT
fnp-3528	1112	50	park	park	PROPN
fnp-3528	1112	51	,	,	PUNCT
fnp-3528	1112	52	s.	s.	PROPN
fnp-3528	1112	53	;	;	PUNCT
fnp-3528	1112	54	shapiro	shapiro	PROPN
fnp-3528	1112	55	,	,	PUNCT
fnp-3528	1112	56	d.	d.	PROPN
fnp-3528	1112	57	j.	j.	PROPN
fnp-3528	1112	58	;	;	PUNCT
fnp-3528	1112	59	nanjappa	nanjappa	PROPN
fnp-3528	1112	60	,	,	PUNCT
fnp-3528	1112	61	s.	s.	PROPN
fnp-3528	1112	62	g.	g.	PROPN
fnp-3528	1112	63	;	;	PUNCT
fnp-3528	1112	64	nelson	nelson	PROPN
fnp-3528	1112	65	,	,	PUNCT
fnp-3528	1112	66	e.	e.	PROPN
fnp-3528	1112	67	r.	r.	PROPN
fnp-3528	1112	68	27	27	NUM
fnp-3528	1112	69	-	-	PUNCT
fnp-3528	1112	70	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	1112	71	acts	act	NOUN
fnp-3528	1112	72	on	on	ADP
fnp-3528	1112	73	myeloid	myeloid	ADJ
fnp-3528	1112	74	immune	immune	ADJ
fnp-3528	1112	75	cells	cell	NOUN
fnp-3528	1112	76	to	to	PART
fnp-3528	1112	77	induce	induce	VERB
fnp-3528	1112	78	t	t	NOUN
fnp-3528	1112	79	cell	cell	NOUN
fnp-3528	1112	80	dysfunction	dysfunction	NOUN
fnp-3528	1112	81	,	,	PUNCT
fnp-3528	1112	82	promoting	promote	VERB
fnp-3528	1112	83	breast	breast	NOUN
fnp-3528	1112	84	cancer	cancer	NOUN
fnp-3528	1112	85	progression	progression	NOUN
fnp-3528	1112	86	.	.	PUNCT
fnp-3528	1113	1	cancer	cancer	NOUN
fnp-3528	1113	2	lett	lett	PROPN
fnp-3528	1113	3	2020	2020	NUM
fnp-3528	1113	4	,	,	PUNCT
fnp-3528	1113	5	493	493	NUM
fnp-3528	1113	6	,	,	PUNCT
fnp-3528	1113	7	266	266	NUM
fnp-3528	1113	8	-	-	SYM
fnp-3528	1113	9	83	83	NUM
fnp-3528	1113	10	.	.	PUNCT
fnp-3528	1114	1	ray	ray	PROPN
fnp-3528	1114	2	,	,	PUNCT
fnp-3528	1114	3	a.	a.	NOUN
fnp-3528	1114	4	g.	g.	PROPN
fnp-3528	1114	5	;	;	PUNCT
fnp-3528	1114	6	choudhury	choudhury	PROPN
fnp-3528	1114	7	,	,	PUNCT
fnp-3528	1114	8	k.	k.	PROPN
fnp-3528	1114	9	r.	r.	PROPN
fnp-3528	1114	10	;	;	PUNCT
fnp-3528	1114	11	chakraborty	chakraborty	PROPN
fnp-3528	1114	12	,	,	PUNCT
fnp-3528	1114	13	s.	s.	PROPN
fnp-3528	1114	14	;	;	PUNCT
fnp-3528	1114	15	chakravarty	chakravarty	NOUN
fnp-3528	1114	16	,	,	PUNCT
fnp-3528	1114	17	d.	d.	PROPN
fnp-3528	1114	18	;	;	PUNCT
fnp-3528	1114	19	chander	chander	PROPN
fnp-3528	1114	20	,	,	PUNCT
fnp-3528	1114	21	v.	v.	PROPN
fnp-3528	1114	22	;	;	PUNCT
fnp-3528	1114	23	jana	jana	PROPN
fnp-3528	1114	24	,	,	PUNCT
fnp-3528	1114	25	b.	b.	PROPN
fnp-3528	1114	26	;	;	PUNCT
fnp-3528	1114	27	siddiqui	siddiqui	NOUN
fnp-3528	1114	28	,	,	PUNCT
fnp-3528	1114	29	k.	k.	PROPN
fnp-3528	1114	30	n.	n.	PROPN
fnp-3528	1114	31	;	;	PUNCT
fnp-3528	1114	32	bandyopadhyay	bandyopadhyay	NOUN
fnp-3528	1114	33	,	,	PUNCT
fnp-3528	1114	34	a.	a.	NOUN
fnp-3528	1114	35	novel	novel	NOUN
fnp-3528	1114	36	mechanism	mechanism	NOUN
fnp-3528	1114	37	of	of	ADP
fnp-3528	1114	38	cholesterol	cholesterol	NOUN
fnp-3528	1114	39	transport	transport	NOUN
fnp-3528	1114	40	by	by	ADP
fnp-3528	1114	41	abca5	abca5	NOUN
fnp-3528	1114	42	in	in	ADP
fnp-3528	1114	43	macrophages	macrophage	NOUN
fnp-3528	1114	44	and	and	CCONJ
fnp-3528	1114	45	its	its	PRON
fnp-3528	1114	46	role	role	NOUN
fnp-3528	1114	47	in	in	ADP
fnp-3528	1114	48	dyslipidemia	dyslipidemia	NOUN
fnp-3528	1114	49	.	.	PUNCT
fnp-3528	1115	1	j	j	PROPN
fnp-3528	1115	2	mol	mol	ADP
fnp-3528	1115	3	biol	biol	PROPN
fnp-3528	1115	4	2020	2020	NUM
fnp-3528	1115	5	,	,	PUNCT
fnp-3528	1115	6	432	432	NUM
fnp-3528	1115	7	,	,	PUNCT
fnp-3528	1115	8	4922	4922	NUM
fnp-3528	1115	9	-	-	SYM
fnp-3528	1115	10	41	41	NUM
fnp-3528	1115	11	.	.	PUNCT
fnp-3528	1116	1	he	he	PRON
fnp-3528	1116	2	,	,	PUNCT
fnp-3528	1116	3	p.	p.	PROPN
fnp-3528	1116	4	;	;	PUNCT
fnp-3528	1116	5	smith	smith	PROPN
fnp-3528	1116	6	,	,	PUNCT
fnp-3528	1116	7	a.	a.	NOUN
fnp-3528	1116	8	;	;	PUNCT
fnp-3528	1116	9	gelissen	gelissen	PROPN
fnp-3528	1116	10	,	,	PUNCT
fnp-3528	1116	11	i.	i.	PROPN
fnp-3528	1116	12	c.	c.	PROPN
fnp-3528	1116	13	;	;	PUNCT
fnp-3528	1116	14	ammit	ammit	ADV
fnp-3528	1116	15	,	,	PUNCT
fnp-3528	1116	16	a.	a.	PROPN
fnp-3528	1116	17	j.	j.	PROPN
fnp-3528	1117	1	the	the	DET
fnp-3528	1117	2	effect	effect	NOUN
fnp-3528	1117	3	of	of	ADP
fnp-3528	1117	4	statins	statin	NOUN
fnp-3528	1117	5	and	and	CCONJ
fnp-3528	1117	6	the	the	DET
fnp-3528	1117	7	synthetic	synthetic	ADJ
fnp-3528	1117	8	lxr	lxr	NOUN
fnp-3528	1117	9	agonist	agonist	NOUN
fnp-3528	1117	10	t0901317	t0901317	NOUN
fnp-3528	1117	11	on	on	ADP
fnp-3528	1117	12	expression	expression	NOUN
fnp-3528	1117	13	of	of	ADP
fnp-3528	1117	14	abca1	abca1	NOUN
fnp-3528	1117	15	transporter	transporter	NOUN
fnp-3528	1117	16	protein	protein	NOUN
fnp-3528	1117	17	in	in	ADP
fnp-3528	1117	18	human	human	ADJ
fnp-3528	1117	19	lung	lung	NOUN
fnp-3528	1117	20	epithelial	epithelial	ADJ
fnp-3528	1117	21	cell	cell	NOUN
fnp-3528	1117	22	lines	line	NOUN
fnp-3528	1117	23	in	in	ADP
fnp-3528	1117	24	vitro	vitro	X
fnp-3528	1117	25	.	.	PUNCT
fnp-3528	1118	1	pharmacol	pharmacol	PROPN
fnp-3528	1118	2	rep	rep	PROPN
fnp-3528	1118	3	:	:	PUNCT
fnp-3528	1118	4	pr	pr	NOUN
fnp-3528	1118	5	2019	2019	NUM
fnp-3528	1118	6	,	,	PUNCT
fnp-3528	1118	7	71	71	NUM
fnp-3528	1118	8	,	,	PUNCT
fnp-3528	1118	9	1219	1219	NUM
fnp-3528	1118	10	-	-	SYM
fnp-3528	1118	11	26	26	NUM
fnp-3528	1118	12	.	.	PUNCT
fnp-3528	1119	1	leger	leger	NOUN
fnp-3528	1119	2	-	-	PUNCT
fnp-3528	1119	3	charnay	charnay	PROPN
fnp-3528	1119	4	,	,	PUNCT
fnp-3528	1119	5	e.	e.	PROPN
fnp-3528	1119	6	;	;	PUNCT
fnp-3528	1119	7	masson	masson	PROPN
fnp-3528	1119	8	,	,	PUNCT
fnp-3528	1119	9	e.	e.	PROPN
fnp-3528	1119	10	a.	a.	PROPN
fnp-3528	1119	11	y.	y.	PROPN
fnp-3528	1119	12	;	;	PUNCT
fnp-3528	1119	13	morala	morala	NOUN
fnp-3528	1119	14	,	,	PUNCT
fnp-3528	1119	15	t.	t.	PROPN
fnp-3528	1119	16	;	;	PUNCT
fnp-3528	1119	17	martine	martine	PROPN
fnp-3528	1119	18	,	,	PUNCT
fnp-3528	1119	19	l.	l.	PROPN
fnp-3528	1119	20	;	;	PUNCT
fnp-3528	1119	21	buteau	buteau	PROPN
fnp-3528	1119	22	,	,	PUNCT
fnp-3528	1119	23	b.	b.	PROPN
fnp-3528	1119	24	;	;	PUNCT
fnp-3528	1119	25	leclere	leclere	ADV
fnp-3528	1119	26	,	,	PUNCT
fnp-3528	1119	27	l.	l.	PROPN
fnp-3528	1119	28	;	;	PUNCT
fnp-3528	1119	29	bretillon	bretillon	PROPN
fnp-3528	1119	30	,	,	PUNCT
fnp-3528	1119	31	l.	l.	PROPN
fnp-3528	1119	32	;	;	PUNCT
fnp-3528	1119	33	gambert	gambert	PROPN
fnp-3528	1119	34	,	,	PUNCT
fnp-3528	1119	35	s.	s.	PROPN
fnp-3528	1119	36	is	be	AUX
fnp-3528	1119	37	24(s)-hydroxycholesterol	24(s)-hydroxycholesterol	NOUN
fnp-3528	1119	38	a	a	DET
fnp-3528	1119	39	potent	potent	ADJ
fnp-3528	1119	40	modulator	modulator	NOUN
fnp-3528	1119	41	of	of	ADP
fnp-3528	1119	42	cholesterol	cholesterol	NOUN
fnp-3528	1119	43	metabolism	metabolism	NOUN
fnp-3528	1119	44	in	in	ADP
fnp-3528	1119	45	muller	muller	NOUN
fnp-3528	1119	46	cells	cell	NOUN
fnp-3528	1119	47	?	?	PUNCT
fnp-3528	1120	1	an	an	DET
fnp-3528	1120	2	in	in	ADP
fnp-3528	1120	3	vitro	vitro	X
fnp-3528	1120	4	study	study	NOUN
fnp-3528	1120	5	about	about	ADP
fnp-3528	1120	6	neuron	neuron	NOUN
fnp-3528	1120	7	to	to	PART
fnp-3528	1120	8	glia	glia	VERB
fnp-3528	1120	9	communication	communication	NOUN
fnp-3528	1120	10	in	in	ADP
fnp-3528	1120	11	the	the	DET
fnp-3528	1120	12	retina	retina	NOUN
fnp-3528	1120	13	.	.	PUNCT
fnp-3528	1121	1	exp	exp	NOUN
fnp-3528	1121	2	eye	eye	NOUN
fnp-3528	1121	3	res	re	NOUN
fnp-3528	1121	4	2019	2019	NUM
fnp-3528	1121	5	,	,	PUNCT
fnp-3528	1121	6	189	189	NUM
fnp-3528	1121	7	,	,	PUNCT
fnp-3528	1121	8	107857	107857	NUM
fnp-3528	1121	9	.	.	PUNCT
fnp-3528	1122	1	wu	wu	PROPN
fnp-3528	1122	2	,	,	PUNCT
fnp-3528	1122	3	c.	c.	PROPN
fnp-3528	1122	4	a.	a.	PROPN
fnp-3528	1122	5	;	;	PUNCT
fnp-3528	1122	6	wang	wang	PROPN
fnp-3528	1122	7	,	,	PUNCT
fnp-3528	1122	8	n.	n.	PROPN
fnp-3528	1122	9	;	;	PUNCT
fnp-3528	1122	10	zhao	zhao	PROPN
fnp-3528	1122	11	,	,	PUNCT
fnp-3528	1122	12	d.	d.	PROPN
fnp-3528	1122	13	h.	h.	PROPN
fnp-3528	1123	1	an	an	DET
fnp-3528	1123	2	evaluation	evaluation	NOUN
fnp-3528	1123	3	of	of	ADP
fnp-3528	1123	4	the	the	DET
fnp-3528	1123	5	mechanism	mechanism	NOUN
fnp-3528	1123	6	of	of	ADP
fnp-3528	1123	7	abca7	abca7	NOUN
fnp-3528	1123	8	on	on	ADP
fnp-3528	1123	9	cellular	cellular	ADJ
fnp-3528	1123	10	lipid	lipid	NOUN
fnp-3528	1123	11	release	release	NOUN
fnp-3528	1123	12	in	in	ADP
fnp-3528	1123	13	abca7	abca7	PROPN
fnp-3528	1123	14	-	-	PUNCT
fnp-3528	1123	15	hec293	hec293	PROPN
fnp-3528	1123	16	cell	cell	NOUN
fnp-3528	1123	17	.	.	PUNCT
fnp-3528	1124	1	chin	chin	PROPN
fnp-3528	1124	2	med	med	PROPN
fnp-3528	1124	3	j	j	PROPN
fnp-3528	1124	4	2013	2013	NUM
fnp-3528	1124	5	,	,	PUNCT
fnp-3528	1124	6	126	126	NUM
fnp-3528	1124	7	,	,	PUNCT
fnp-3528	1124	8	306	306	NUM
fnp-3528	1124	9	-	-	SYM
fnp-3528	1124	10	10	10	NUM
fnp-3528	1124	11	.	.	PUNCT
fnp-3528	1125	1	lee	lee	PROPN
fnp-3528	1125	2	,	,	PUNCT
fnp-3528	1125	3	j.	j.	PROPN
fnp-3528	1125	4	s.	s.	PROPN
fnp-3528	1125	5	;	;	PUNCT
fnp-3528	1125	6	kim	kim	PROPN
fnp-3528	1125	7	,	,	PUNCT
fnp-3528	1125	8	e.	e.	PROPN
fnp-3528	1125	9	;	;	PUNCT
fnp-3528	1125	10	han	han	PROPN
fnp-3528	1125	11	,	,	PUNCT
fnp-3528	1125	12	s.	s.	PROPN
fnp-3528	1125	13	;	;	PUNCT
fnp-3528	1125	14	kang	kang	PROPN
fnp-3528	1125	15	,	,	PUNCT
fnp-3528	1125	16	k.	k.	PROPN
fnp-3528	1125	17	l.	l.	PROPN
fnp-3528	1125	18	;	;	PUNCT
fnp-3528	1125	19	heo	heo	PROPN
fnp-3528	1125	20	,	,	PUNCT
fnp-3528	1125	21	j.	j.	PROPN
fnp-3528	1125	22	s.	s.	PROPN
fnp-3528	1125	23	evaluating	evaluate	VERB
fnp-3528	1125	24	the	the	DET
fnp-3528	1125	25	oxysterol	oxysterol	NOUN
fnp-3528	1125	26	combination	combination	NOUN
fnp-3528	1125	27	of	of	ADP
fnp-3528	1125	28	22(s)-hydroxycholesterol	22(s)-hydroxycholesterol	NOUN
fnp-3528	1125	29	and	and	CCONJ
fnp-3528	1125	30	20(s)-hydroxycholesterol	20(s)-hydroxycholesterol	PROPN
fnp-3528	1125	31	in	in	ADP
fnp-3528	1125	32	periodontal	periodontal	ADJ
fnp-3528	1125	33	regeneration	regeneration	NOUN
fnp-3528	1125	34	using	use	VERB
fnp-3528	1125	35	periodontal	periodontal	ADJ
fnp-3528	1125	36	ligament	ligament	NOUN
fnp-3528	1125	37	stem	stem	NOUN
fnp-3528	1125	38	cells	cell	NOUN
fnp-3528	1125	39	and	and	CCONJ
fnp-3528	1125	40	alveolar	alveolar	ADJ
fnp-3528	1125	41	bone	bone	NOUN
fnp-3528	1125	42	healing	healing	NOUN
fnp-3528	1125	43	models	model	NOUN
fnp-3528	1125	44	.	.	PUNCT
fnp-3528	1126	1	stem	stem	NOUN
fnp-3528	1126	2	cell	cell	NOUN
fnp-3528	1126	3	res	re	NOUN
fnp-3528	1126	4	ther	ther	ADV
fnp-3528	1126	5	2017	2017	NUM
fnp-3528	1126	6	,	,	PUNCT
fnp-3528	1126	7	8	8	NUM
fnp-3528	1126	8	,	,	PUNCT
fnp-3528	1126	9	276	276	NUM
fnp-3528	1126	10	.	.	PUNCT
fnp-3528	1127	1	panzenboeck	panzenboeck	NOUN
fnp-3528	1127	2	,	,	PUNCT
fnp-3528	1127	3	u.	u.	PROPN
fnp-3528	1127	4	;	;	PUNCT
fnp-3528	1127	5	kratzer	kratzer	PROPN
fnp-3528	1127	6	,	,	PUNCT
fnp-3528	1127	7	i.	i.	PROPN
fnp-3528	1127	8	;	;	PUNCT
fnp-3528	1127	9	sovic	sovic	PROPN
fnp-3528	1127	10	,	,	PUNCT
fnp-3528	1127	11	a.	a.	NOUN
fnp-3528	1127	12	;	;	PUNCT
fnp-3528	1127	13	wintersperger	wintersperger	ADV
fnp-3528	1127	14	,	,	PUNCT
fnp-3528	1127	15	a.	a.	NOUN
fnp-3528	1127	16	;	;	PUNCT
fnp-3528	1127	17	bernhart	bernhart	NOUN
fnp-3528	1127	18	,	,	PUNCT
fnp-3528	1127	19	e.	e.	PROPN
fnp-3528	1127	20	;	;	PUNCT
fnp-3528	1127	21	hammer	hammer	NOUN
fnp-3528	1127	22	,	,	PUNCT
fnp-3528	1127	23	a.	a.	NOUN
fnp-3528	1127	24	;	;	PUNCT
fnp-3528	1127	25	malle	malle	PROPN
fnp-3528	1127	26	,	,	PUNCT
fnp-3528	1127	27	e.	e.	PROPN
fnp-3528	1127	28	;	;	PUNCT
fnp-3528	1127	29	sattler	sattler	PROPN
fnp-3528	1127	30	,	,	PUNCT
fnp-3528	1127	31	w.	w.	PROPN
fnp-3528	1127	32	regulatory	regulatory	ADJ
fnp-3528	1127	33	effects	effect	NOUN
fnp-3528	1127	34	of	of	ADP
fnp-3528	1127	35	synthetic	synthetic	ADJ
fnp-3528	1127	36	liver	liver	NOUN
fnp-3528	1127	37	x	x	X
fnp-3528	1127	38	receptorand	receptorand	NOUN
fnp-3528	1127	39	peroxisome	peroxisome	NOUN
fnp-3528	1127	40	-	-	PUNCT
fnp-3528	1127	41	proliferator	proliferator	NOUN
fnp-3528	1127	42	activated	activate	VERB
fnp-3528	1127	43	receptor	receptor	NOUN
fnp-3528	1127	44	agonists	agonist	NOUN
fnp-3528	1127	45	on	on	ADP
fnp-3528	1127	46	sterol	sterol	NOUN
fnp-3528	1127	47	transport	transport	NOUN
fnp-3528	1127	48	pathways	pathway	NOUN
fnp-3528	1127	49	in	in	ADP
fnp-3528	1127	50	polarized	polarize	VERB
fnp-3528	1127	51	cerebrovascular	cerebrovascular	ADJ
fnp-3528	1127	52	endothelial	endothelial	ADJ
fnp-3528	1127	53	cells	cell	NOUN
fnp-3528	1127	54	.	.	PUNCT
fnp-3528	1128	1	int	int	PROPN
fnp-3528	1128	2	j	j	PROPN
fnp-3528	1128	3	biochem	biochem	PROPN
fnp-3528	1128	4	cell	cell	NOUN
fnp-3528	1128	5	biol	biol	PROPN
fnp-3528	1128	6	2006	2006	NUM
fnp-3528	1128	7	,	,	PUNCT
fnp-3528	1128	8	38	38	NUM
fnp-3528	1128	9	,	,	PUNCT
fnp-3528	1128	10	1314	1314	NUM
fnp-3528	1128	11	-	-	SYM
fnp-3528	1128	12	29	29	NUM
fnp-3528	1128	13	.	.	PUNCT
fnp-3528	1129	1	ruan	ruan	PROPN
fnp-3528	1129	2	,	,	PUNCT
fnp-3528	1129	3	x.	x.	PROPN
fnp-3528	1129	4	z.	z.	PROPN
fnp-3528	1129	5	;	;	PUNCT
fnp-3528	1129	6	moorhead	moorhead	PROPN
fnp-3528	1129	7	,	,	PUNCT
fnp-3528	1129	8	j.	j.	PROPN
fnp-3528	1129	9	f.	f.	PROPN
fnp-3528	1129	10	;	;	PUNCT
fnp-3528	1129	11	fernando	fernando	PROPN
fnp-3528	1129	12	,	,	PUNCT
fnp-3528	1129	13	r.	r.	PROPN
fnp-3528	1129	14	;	;	PUNCT
fnp-3528	1129	15	wheeler	wheeler	NOUN
fnp-3528	1129	16	,	,	PUNCT
fnp-3528	1129	17	d.	d.	PROPN
fnp-3528	1129	18	c.	c.	PROPN
fnp-3528	1129	19	;	;	PUNCT
fnp-3528	1129	20	powis	powis	PROPN
fnp-3528	1129	21	,	,	PUNCT
fnp-3528	1129	22	s.	s.	PROPN
fnp-3528	1129	23	h.	h.	PROPN
fnp-3528	1129	24	;	;	PUNCT
fnp-3528	1129	25	varghese	varghese	PROPN
fnp-3528	1129	26	,	,	PUNCT
fnp-3528	1129	27	z.	z.	PROPN
fnp-3528	1129	28	ppar	ppar	PROPN
fnp-3528	1129	29	agonists	agonist	NOUN
fnp-3528	1129	30	protect	protect	VERB
fnp-3528	1129	31	mesangial	mesangial	ADJ
fnp-3528	1129	32	cells	cell	NOUN
fnp-3528	1129	33	from	from	ADP
fnp-3528	1129	34	interleukin	interleukin	NOUN
fnp-3528	1129	35	1beta	1beta	PROPN
fnp-3528	1129	36	-	-	PUNCT
fnp-3528	1129	37	induced	induced	ADJ
fnp-3528	1129	38	intracellular	intracellular	ADJ
fnp-3528	1129	39	lipid	lipid	NOUN
fnp-3528	1129	40	accumulation	accumulation	NOUN
fnp-3528	1129	41	by	by	ADP
fnp-3528	1129	42	activating	activate	VERB
fnp-3528	1129	43	the	the	DET
fnp-3528	1129	44	abca1	abca1	NOUN
fnp-3528	1129	45	cholesterol	cholesterol	NOUN
fnp-3528	1129	46	efflux	efflux	NOUN
fnp-3528	1129	47	pathway	pathway	NOUN
fnp-3528	1129	48	.	.	PUNCT
fnp-3528	1130	1	j	j	PROPN
fnp-3528	1130	2	am	be	AUX
fnp-3528	1130	3	soc	soc	NOUN
fnp-3528	1130	4	nephrol	nephrol	NOUN
fnp-3528	1130	5	2003	2003	NUM
fnp-3528	1130	6	,	,	PUNCT
fnp-3528	1130	7	14	14	NUM
fnp-3528	1130	8	,	,	PUNCT
fnp-3528	1130	9	593	593	NUM
fnp-3528	1130	10	-	-	SYM
fnp-3528	1130	11	600	600	NUM
fnp-3528	1130	12	.	.	PUNCT
fnp-3528	1131	1	kim	kim	PROPN
fnp-3528	1131	2	,	,	PUNCT
fnp-3528	1131	3	b.	b.	PROPN
fnp-3528	1131	4	y.	y.	PROPN
fnp-3528	1131	5	;	;	PUNCT
fnp-3528	1131	6	son	son	NOUN
fnp-3528	1131	7	,	,	PUNCT
fnp-3528	1131	8	y.	y.	PROPN
fnp-3528	1131	9	;	;	PUNCT
fnp-3528	1131	10	cho	cho	PROPN
fnp-3528	1131	11	,	,	PUNCT
fnp-3528	1131	12	h.	h.	PROPN
fnp-3528	1131	13	r.	r.	PROPN
fnp-3528	1131	14	;	;	PUNCT
fnp-3528	1131	15	lee	lee	PROPN
fnp-3528	1131	16	,	,	PUNCT
fnp-3528	1131	17	d.	d.	PROPN
fnp-3528	1131	18	;	;	PUNCT
fnp-3528	1131	19	eo	eo	PROPN
fnp-3528	1131	20	,	,	PUNCT
fnp-3528	1131	21	s.	s.	PROPN
fnp-3528	1131	22	k.	k.	PROPN
fnp-3528	1131	23	;	;	PUNCT
fnp-3528	1131	24	kim	kim	PROPN
fnp-3528	1131	25	,	,	PUNCT
fnp-3528	1131	26	k.	k.	PROPN
fnp-3528	1131	27	27	27	NUM
fnp-3528	1131	28	-	-	PUNCT
fnp-3528	1131	29	hydroxycholesterol	hydroxycholesterol	NOUN
fnp-3528	1131	30	induces	induce	VERB
fnp-3528	1131	31	macrophage	macrophage	ADJ
fnp-3528	1131	32	gene	gene	NOUN
fnp-3528	1131	33	expression	expression	NOUN
fnp-3528	1131	34	via	via	ADP
fnp-3528	1131	35	lxr	lxr	PROPN
fnp-3528	1131	36	-	-	PUNCT
fnp-3528	1131	37	dependent	dependent	ADJ
fnp-3528	1131	38	and	and	CCONJ
fnp-3528	1131	39	-independent	-independent	ADJ
fnp-3528	1131	40	mechanisms	mechanism	NOUN
fnp-3528	1131	41	.	.	PUNCT
fnp-3528	1132	1	korean	korean	PROPN
fnp-3528	1132	2	j	j	PROPN
fnp-3528	1132	3	physiol	physiol	PROPN
fnp-3528	1132	4	pharmacol	pharmacol	PROPN
fnp-3528	1132	5	2021	2021	NUM
fnp-3528	1132	6	,	,	PUNCT
fnp-3528	1132	7	25	25	NUM
fnp-3528	1132	8	,	,	PUNCT
fnp-3528	1132	9	111	111	NUM
fnp-3528	1132	10	-	-	SYM
fnp-3528	1132	11	8	8	NUM
fnp-3528	1132	12	.	.	PUNCT
fnp-3528	1132	13	costet	costet	NOUN
fnp-3528	1132	14	,	,	PUNCT
fnp-3528	1132	15	p.	p.	NOUN
fnp-3528	1132	16	;	;	PUNCT
fnp-3528	1132	17	lalanne	lalanne	PROPN
fnp-3528	1132	18	,	,	PUNCT
fnp-3528	1132	19	f.	f.	PROPN
fnp-3528	1132	20	;	;	PUNCT
fnp-3528	1132	21	gerbod	gerbod	NOUN
fnp-3528	1132	22	-	-	PUNCT
fnp-3528	1132	23	giannone	giannone	NOUN
fnp-3528	1132	24	,	,	PUNCT
fnp-3528	1132	25	m.	m.	NOUN
fnp-3528	1132	26	c.	c.	PROPN
fnp-3528	1132	27	;	;	PUNCT
fnp-3528	1132	28	molina	molina	PROPN
fnp-3528	1132	29	,	,	PUNCT
fnp-3528	1132	30	j.	j.	PROPN
fnp-3528	1132	31	r.	r.	PROPN
fnp-3528	1132	32	;	;	PUNCT
fnp-3528	1132	33	fu	fu	PROPN
fnp-3528	1132	34	,	,	PUNCT
fnp-3528	1132	35	x.	x.	PROPN
fnp-3528	1132	36	;	;	PUNCT
fnp-3528	1132	37	lund	lund	PROPN
fnp-3528	1132	38	,	,	PUNCT
fnp-3528	1132	39	e.	e.	PROPN
fnp-3528	1132	40	g.	g.	PROPN
fnp-3528	1132	41	;	;	PUNCT
fnp-3528	1132	42	gudas	gudas	PROPN
fnp-3528	1132	43	,	,	PUNCT
fnp-3528	1132	44	l.	l.	PROPN
fnp-3528	1132	45	j.	j.	PROPN
fnp-3528	1132	46	;	;	PUNCT
fnp-3528	1132	47	tall	tall	ADJ
fnp-3528	1132	48	,	,	PUNCT
fnp-3528	1132	49	a.	a.	PROPN
fnp-3528	1132	50	r.	r.	PROPN
fnp-3528	1132	51	retinoic	retinoic	PROPN
fnp-3528	1132	52	acid	acid	PROPN
fnp-3528	1132	53	receptor	receptor	NOUN
fnp-3528	1132	54	-	-	PUNCT
fnp-3528	1132	55	mediated	mediate	VERB
fnp-3528	1132	56	induction	induction	NOUN
fnp-3528	1132	57	of	of	ADP
fnp-3528	1132	58	abca1	abca1	NOUN
fnp-3528	1132	59	in	in	ADP
fnp-3528	1132	60	macrophages	macrophage	NOUN
fnp-3528	1132	61	.	.	PUNCT
fnp-3528	1133	1	mol	mol	ADP
fnp-3528	1133	2	cell	cell	NOUN
fnp-3528	1133	3	biol	biol	NOUN
fnp-3528	1133	4	2003	2003	NUM
fnp-3528	1133	5	,	,	PUNCT
fnp-3528	1133	6	23	23	NUM
fnp-3528	1133	7	,	,	PUNCT
fnp-3528	1133	8	7756	7756	NUM
fnp-3528	1133	9	-	-	SYM
fnp-3528	1133	10	66	66	NUM
fnp-3528	1133	11	.	.	PUNCT
fnp-3528	1134	1	zhang	zhang	PROPN
fnp-3528	1134	2	,	,	PUNCT
fnp-3528	1134	3	c.	c.	PROPN
fnp-3528	1134	4	j.	j.	PROPN
fnp-3528	1134	5	;	;	PUNCT
fnp-3528	1134	6	zhu	zhu	PROPN
fnp-3528	1134	7	,	,	PUNCT
fnp-3528	1134	8	n.	n.	NOUN
fnp-3528	1134	9	;	;	PUNCT
fnp-3528	1134	10	long	long	ADV
fnp-3528	1134	11	,	,	PUNCT
fnp-3528	1134	12	j.	j.	PROPN
fnp-3528	1134	13	;	;	PUNCT
fnp-3528	1134	14	wu	wu	PROPN
fnp-3528	1134	15	,	,	PUNCT
fnp-3528	1134	16	h.	h.	PROPN
fnp-3528	1134	17	t.	t.	PROPN
fnp-3528	1134	18	;	;	PUNCT
fnp-3528	1134	19	wang	wang	PROPN
fnp-3528	1134	20	,	,	PUNCT
fnp-3528	1134	21	y.	y.	PROPN
fnp-3528	1134	22	x.	x.	PROPN
fnp-3528	1134	23	;	;	PUNCT
fnp-3528	1134	24	liu	liu	PROPN
fnp-3528	1134	25	,	,	PUNCT
fnp-3528	1134	26	b.	b.	PROPN
fnp-3528	1134	27	y.	y.	PROPN
fnp-3528	1134	28	;	;	PUNCT
fnp-3528	1134	29	liao	liao	PROPN
fnp-3528	1134	30	,	,	PUNCT
fnp-3528	1134	31	d.	d.	PROPN
fnp-3528	1134	32	f.	f.	PROPN
fnp-3528	1134	33	;	;	PUNCT
fnp-3528	1134	34	qin	qin	PROPN
fnp-3528	1134	35	,	,	PUNCT
fnp-3528	1134	36	l.	l.	PROPN
fnp-3528	1134	37	celastrol	celastrol	PROPN
fnp-3528	1134	38	induces	induce	VERB
fnp-3528	1134	39	lipophagy	lipophagy	NOUN
fnp-3528	1134	40	via	via	ADP
fnp-3528	1134	41	the	the	DET
fnp-3528	1134	42	lxralpha	lxralpha	NOUN
fnp-3528	1134	43	/	/	SYM
fnp-3528	1134	44	abca1	abca1	NOUN
fnp-3528	1134	45	pathway	pathway	NOUN
fnp-3528	1134	46	in	in	ADP
fnp-3528	1134	47	clear	clear	ADJ
fnp-3528	1134	48	cell	cell	NOUN
fnp-3528	1134	49	renal	renal	ADJ
fnp-3528	1134	50	cell	cell	NOUN
fnp-3528	1134	51	carcinoma	carcinoma	NOUN
fnp-3528	1134	52	.	.	PUNCT
fnp-3528	1135	1	acta	acta	PROPN
fnp-3528	1135	2	pharmacol	pharmacol	PROPN
fnp-3528	1135	3	sin	sin	NOUN
fnp-3528	1135	4	2020	2020	NUM
fnp-3528	1135	5	,	,	PUNCT
fnp-3528	1135	6	42	42	NUM
fnp-3528	1135	7	,	,	PUNCT
fnp-3528	1135	8	1472	1472	NUM
fnp-3528	1135	9	-	-	SYM
fnp-3528	1135	10	85	85	NUM
fnp-3528	1135	11	.	.	PUNCT
fnp-3528	1136	1	munir	munir	PROPN
fnp-3528	1136	2	,	,	PUNCT
fnp-3528	1136	3	m.	m.	NOUN
fnp-3528	1136	4	t.	t.	PROPN
fnp-3528	1136	5	;	;	PUNCT
fnp-3528	1136	6	ponce	ponce	PROPN
fnp-3528	1136	7	,	,	PUNCT
fnp-3528	1136	8	c.	c.	PROPN
fnp-3528	1136	9	;	;	PUNCT
fnp-3528	1136	10	santos	santos	PROPN
fnp-3528	1136	11	,	,	PUNCT
fnp-3528	1136	12	j.	j.	PROPN
fnp-3528	1136	13	m.	m.	PROPN
fnp-3528	1136	14	;	;	PUNCT
fnp-3528	1136	15	sufian	sufian	PROPN
fnp-3528	1136	16	,	,	PUNCT
fnp-3528	1136	17	h.	h.	PROPN
fnp-3528	1136	18	b.	b.	PROPN
fnp-3528	1136	19	;	;	PUNCT
fnp-3528	1136	20	al	al	PROPN
fnp-3528	1136	21	-	-	PUNCT
fnp-3528	1136	22	harrasi	harrasi	NOUN
fnp-3528	1136	23	,	,	PUNCT
fnp-3528	1136	24	a.	a.	NOUN
fnp-3528	1136	25	;	;	PUNCT
fnp-3528	1136	26	gollahon	gollahon	PROPN
fnp-3528	1136	27	,	,	PUNCT
fnp-3528	1136	28	l.	l.	PROPN
fnp-3528	1136	29	s.	s.	PROPN
fnp-3528	1136	30	;	;	PUNCT
fnp-3528	1136	31	hussain	hussain	PROPN
fnp-3528	1136	32	,	,	PUNCT
fnp-3528	1136	33	f.	f.	PROPN
fnp-3528	1136	34	;	;	PUNCT
fnp-3528	1136	35	rahman	rahman	PROPN
fnp-3528	1136	36	,	,	PUNCT
fnp-3528	1136	37	s.	s.	PROPN
fnp-3528	1136	38	m.	m.	PROPN
fnp-3528	1136	39	vd3	vd3	NOUN
fnp-3528	1136	40	and	and	CCONJ
fnp-3528	1136	41	lxr	lxr	PROPN
fnp-3528	1136	42	agonist	agonist	NOUN
fnp-3528	1136	43	(	(	PUNCT
fnp-3528	1136	44	t0901317	t0901317	NOUN
fnp-3528	1136	45	)	)	PUNCT
fnp-3528	1136	46	combination	combination	NOUN
fnp-3528	1136	47	demonstrated	demonstrate	VERB
fnp-3528	1136	48	greater	great	ADJ
fnp-3528	1136	49	potency	potency	NOUN
fnp-3528	1136	50	in	in	ADP
fnp-3528	1136	51	inhibiting	inhibit	VERB
fnp-3528	1136	52	cholesterol	cholesterol	NOUN
fnp-3528	1136	53	accumulation	accumulation	NOUN
fnp-3528	1136	54	and	and	CCONJ
fnp-3528	1136	55	inducing	induce	VERB
fnp-3528	1136	56	apoptosis	apoptosis	NOUN
fnp-3528	1136	57	via	via	ADP
fnp-3528	1136	58	abca1	abca1	NOUN
fnp-3528	1136	59	-	-	PUNCT
fnp-3528	1136	60	chop	chop	NOUN
fnp-3528	1136	61	-	-	PUNCT
fnp-3528	1136	62	bcl-2	bcl-2	NOUN
fnp-3528	1136	63	cascade	cascade	NOUN
fnp-3528	1136	64	in	in	ADP
fnp-3528	1136	65	mcf-7	mcf-7	PUNCT
fnp-3528	1136	66	breast	breast	NOUN
fnp-3528	1136	67	cancer	cancer	NOUN
fnp-3528	1136	68	cells	cell	NOUN
fnp-3528	1136	69	.	.	PUNCT
fnp-3528	1137	1	mol	mol	ADP
fnp-3528	1137	2	biol	biol	PROPN
fnp-3528	1137	3	rep	rep	PROPN
fnp-3528	1137	4	2020	2020	NUM
fnp-3528	1137	5	,	,	PUNCT
fnp-3528	1137	6	47	47	NUM
fnp-3528	1137	7	,	,	PUNCT
fnp-3528	1137	8	7771	7771	NUM
fnp-3528	1137	9	-	-	SYM
fnp-3528	1137	10	82	82	NUM
fnp-3528	1137	11	.	.	PUNCT
fnp-3528	1138	1	shi	shi	PROPN
fnp-3528	1138	2	,	,	PUNCT
fnp-3528	1138	3	y.	y.	PROPN
fnp-3528	1138	4	;	;	PUNCT
fnp-3528	1138	5	jiang	jiang	PROPN
fnp-3528	1138	6	,	,	PUNCT
fnp-3528	1138	7	s.	s.	PROPN
fnp-3528	1138	8	;	;	PUNCT
fnp-3528	1138	9	zhao	zhao	X
fnp-3528	1138	10	,	,	PUNCT
fnp-3528	1138	11	t.	t.	PROPN
fnp-3528	1138	12	;	;	PUNCT
fnp-3528	1138	13	gong	gong	PROPN
fnp-3528	1138	14	,	,	PUNCT
fnp-3528	1138	15	y.	y.	PROPN
fnp-3528	1138	16	;	;	PUNCT
fnp-3528	1138	17	liao	liao	PROPN
fnp-3528	1138	18	,	,	PUNCT
fnp-3528	1138	19	d.	d.	PROPN
fnp-3528	1138	20	;	;	PUNCT
fnp-3528	1138	21	qin	qin	PROPN
fnp-3528	1138	22	,	,	PUNCT
fnp-3528	1138	23	l.	l.	PROPN
fnp-3528	1138	24	celastrol	celastrol	PROPN
fnp-3528	1138	25	suppresses	suppress	VERB
fnp-3528	1138	26	lipid	lipid	ADJ
fnp-3528	1138	27	accumulation	accumulation	NOUN
fnp-3528	1138	28	through	through	ADP
fnp-3528	1138	29	lxralpha	lxralpha	PROPN
fnp-3528	1138	30	/	/	SYM
fnp-3528	1138	31	abca1	abca1	NOUN
fnp-3528	1138	32	signaling	signal	VERB
fnp-3528	1138	33	pathway	pathway	NOUN
fnp-3528	1138	34	and	and	CCONJ
fnp-3528	1138	35	autophagy	autophagy	VERB
fnp-3528	1138	36	in	in	ADP
fnp-3528	1138	37	vascular	vascular	ADJ
fnp-3528	1138	38	smooth	smooth	ADJ
fnp-3528	1138	39	muscle	muscle	NOUN
fnp-3528	1138	40	cells	cell	NOUN
fnp-3528	1138	41	.	.	PUNCT
fnp-3528	1139	1	biochem	biochem	PROPN
fnp-3528	1139	2	biophys	biophys	PROPN
fnp-3528	1139	3	res	res	PROPN
fnp-3528	1139	4	commun	commun	PROPN
fnp-3528	1139	5	2020	2020	NUM
fnp-3528	1139	6	,	,	PUNCT
fnp-3528	1139	7	532	532	NUM
fnp-3528	1139	8	,	,	PUNCT
fnp-3528	1139	9	466	466	NUM
fnp-3528	1139	10	-	-	SYM
fnp-3528	1139	11	74	74	NUM
fnp-3528	1139	12	.	.	PUNCT
fnp-3528	1140	1	warde	warde	PROPN
fnp-3528	1140	2	,	,	PUNCT
fnp-3528	1140	3	k.	k.	PROPN
fnp-3528	1140	4	m.	m.	PROPN
fnp-3528	1140	5	;	;	PUNCT
fnp-3528	1140	6	schoenmakers	schoenmaker	NOUN
fnp-3528	1140	7	,	,	PUNCT
fnp-3528	1140	8	e.	e.	PROPN
fnp-3528	1140	9	;	;	PUNCT
fnp-3528	1140	10	ribes	ribes	PROPN
fnp-3528	1140	11	martinez	martinez	PROPN
fnp-3528	1140	12	,	,	PUNCT
fnp-3528	1140	13	e.	e.	PROPN
fnp-3528	1140	14	;	;	PUNCT
fnp-3528	1140	15	lim	lim	PROPN
fnp-3528	1140	16	,	,	PUNCT
fnp-3528	1140	17	y.	y.	PROPN
fnp-3528	1140	18	j.	j.	PROPN
fnp-3528	1140	19	;	;	PUNCT
fnp-3528	1140	20	leonard	leonard	PROPN
fnp-3528	1140	21	,	,	PUNCT
fnp-3528	1140	22	m.	m.	NOUN
fnp-3528	1140	23	;	;	PUNCT
fnp-3528	1140	24	lawless	lawless	ADJ
fnp-3528	1140	25	,	,	PUNCT
fnp-3528	1140	26	s.	s.	PROPN
fnp-3528	1140	27	j.	j.	PROPN
fnp-3528	1140	28	;	;	PUNCT
fnp-3528	1140	29	o'shea	o'shea	PROPN
fnp-3528	1140	30	,	,	PUNCT
fnp-3528	1140	31	p.	p.	PROPN
fnp-3528	1140	32	;	;	PUNCT
fnp-3528	1140	33	chatterjee	chatterjee	PROPN
fnp-3528	1140	34	,	,	PUNCT
fnp-3528	1140	35	k.	k.	PROPN
fnp-3528	1141	1	v.	v.	PROPN
fnp-3528	1141	2	;	;	PUNCT
fnp-3528	1141	3	gurnell	gurnell	ADJ
fnp-3528	1141	4	,	,	PUNCT
fnp-3528	1141	5	m.	m.	NOUN
fnp-3528	1141	6	;	;	PUNCT
fnp-3528	1141	7	hantel	hantel	NOUN
fnp-3528	1141	8	,	,	PUNCT
fnp-3528	1141	9	c.	c.	NOUN
fnp-3528	1141	10	;	;	PUNCT
fnp-3528	1141	11	dennedy	dennedy	NOUN
fnp-3528	1141	12	,	,	PUNCT
fnp-3528	1141	13	m.	m.	NOUN
fnp-3528	1141	14	c.	c.	PROPN
fnp-3528	1141	15	liver	liver	NOUN
fnp-3528	1142	1	x	x	ADP
fnp-3528	1142	2	receptor	receptor	NOUN
fnp-3528	1142	3	inhibition	inhibition	NOUN
fnp-3528	1142	4	potentiates	potentiate	VERB
fnp-3528	1142	5	mitotane	mitotane	NOUN
fnp-3528	1142	6	-	-	PUNCT
fnp-3528	1142	7	induced	induce	VERB
fnp-3528	1142	8	adrenotoxicity	adrenotoxicity	NOUN
fnp-3528	1142	9	in	in	ADP
fnp-3528	1142	10	acc	acc	PROPN
fnp-3528	1142	11	.	.	PUNCT
fnp-3528	1143	1	endocr	endocr	PROPN
fnp-3528	1143	2	relat	relat	PROPN
fnp-3528	1143	3	cancer	cancer	NOUN
fnp-3528	1143	4	2020	2020	NUM
fnp-3528	1143	5	,	,	PUNCT
fnp-3528	1143	6	27	27	NUM
fnp-3528	1143	7	,	,	PUNCT
fnp-3528	1143	8	361	361	NUM
fnp-3528	1143	9	-	-	SYM
fnp-3528	1143	10	73	73	NUM
fnp-3528	1143	11	.	.	PUNCT
fnp-3528	1144	1	wu	wu	PROPN
fnp-3528	1144	2	,	,	PUNCT
fnp-3528	1144	3	g.	g.	PROPN
fnp-3528	1144	4	;	;	PUNCT
fnp-3528	1144	5	wang	wang	PROPN
fnp-3528	1144	6	,	,	PUNCT
fnp-3528	1144	7	q.	q.	PROPN
fnp-3528	1144	8	;	;	PUNCT
fnp-3528	1144	9	xu	xu	PROPN
fnp-3528	1144	10	,	,	PUNCT
fnp-3528	1144	11	y.	y.	PROPN
fnp-3528	1144	12	;	;	PUNCT
fnp-3528	1144	13	li	li	PROPN
fnp-3528	1144	14	,	,	PUNCT
fnp-3528	1144	15	j.	j.	PROPN
fnp-3528	1144	16	;	;	PUNCT
fnp-3528	1144	17	zhang	zhang	PROPN
fnp-3528	1144	18	,	,	PUNCT
fnp-3528	1144	19	h.	h.	PROPN
fnp-3528	1144	20	;	;	PUNCT
fnp-3528	1144	21	qi	qi	PROPN
fnp-3528	1144	22	,	,	PUNCT
fnp-3528	1144	23	g.	g.	PROPN
fnp-3528	1144	24	;	;	PUNCT
fnp-3528	1144	25	xia	xia	PROPN
fnp-3528	1144	26	,	,	PUNCT
fnp-3528	1144	27	q.	q.	PROPN
fnp-3528	1144	28	targeting	target	VERB
fnp-3528	1144	29	the	the	DET
fnp-3528	1144	30	transcription	transcription	NOUN
fnp-3528	1144	31	factor	factor	NOUN
fnp-3528	1144	32	receptor	receptor	NOUN
fnp-3528	1144	33	lxr	lxr	NOUN
fnp-3528	1144	34	to	to	PART
fnp-3528	1144	35	treat	treat	VERB
fnp-3528	1144	36	clear	clear	ADJ
fnp-3528	1144	37	cell	cell	NOUN
fnp-3528	1144	38	renal	renal	ADJ
fnp-3528	1144	39	cell	cell	NOUN
fnp-3528	1144	40	carcinoma	carcinoma	NOUN
fnp-3528	1144	41	:	:	PUNCT
fnp-3528	1144	42	agonist	agonist	NOUN
fnp-3528	1144	43	or	or	CCONJ
fnp-3528	1144	44	inverse	inverse	ADJ
fnp-3528	1144	45	agonist	agonist	NOUN
fnp-3528	1144	46	?	?	PUNCT
fnp-3528	1145	1	cell	cell	NOUN
fnp-3528	1145	2	death	death	NOUN
fnp-3528	1145	3	dis	dis	PROPN
fnp-3528	1145	4	2019	2019	NUM
fnp-3528	1145	5	,	,	PUNCT
fnp-3528	1145	6	10	10	NUM
fnp-3528	1145	7	,	,	PUNCT
fnp-3528	1145	8	416	416	NUM
fnp-3528	1145	9	.	.	PUNCT
fnp-3528	1146	1	jin	jin	NOUN
fnp-3528	1146	2	,	,	PUNCT
fnp-3528	1146	3	p.	p.	NOUN
fnp-3528	1146	4	;	;	PUNCT
fnp-3528	1146	5	bian	bian	PROPN
fnp-3528	1146	6	,	,	PUNCT
fnp-3528	1146	7	y.	y.	PROPN
fnp-3528	1146	8	;	;	PUNCT
fnp-3528	1146	9	wang	wang	PROPN
fnp-3528	1146	10	,	,	PUNCT
fnp-3528	1146	11	k.	k.	PROPN
fnp-3528	1146	12	;	;	PUNCT
fnp-3528	1146	13	cong	cong	PROPN
fnp-3528	1146	14	,	,	PUNCT
fnp-3528	1146	15	g.	g.	PROPN
fnp-3528	1146	16	;	;	PUNCT
fnp-3528	1146	17	yan	yan	PROPN
fnp-3528	1146	18	,	,	PUNCT
fnp-3528	1146	19	r.	r.	PROPN
fnp-3528	1146	20	;	;	PUNCT
fnp-3528	1146	21	sha	sha	PROPN
fnp-3528	1146	22	,	,	PUNCT
fnp-3528	1146	23	y.	y.	PROPN
fnp-3528	1146	24	;	;	PUNCT
fnp-3528	1146	25	ma	ma	PROPN
fnp-3528	1146	26	,	,	PUNCT
fnp-3528	1146	27	x.	x.	PROPN
fnp-3528	1146	28	;	;	PUNCT
fnp-3528	1146	29	zhou	zhou	PROPN
fnp-3528	1146	30	,	,	PUNCT
fnp-3528	1146	31	j.	j.	PROPN
fnp-3528	1146	32	;	;	PUNCT
fnp-3528	1146	33	yuan	yuan	PROPN
fnp-3528	1146	34	,	,	PUNCT
fnp-3528	1146	35	z.	z.	PROPN
fnp-3528	1146	36	;	;	PUNCT
fnp-3528	1146	37	jia	jia	PROPN
fnp-3528	1146	38	,	,	PUNCT
fnp-3528	1146	39	s.	s.	PROPN
fnp-3528	1146	40	homocysteine	homocysteine	PROPN
fnp-3528	1146	41	accelerates	accelerate	VERB
fnp-3528	1146	42	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1146	43	via	via	ADP
fnp-3528	1146	44	inhibiting	inhibit	VERB
fnp-3528	1146	45	lxralpha	lxralpha	NOUN
fnp-3528	1146	46	-	-	PUNCT
fnp-3528	1146	47	mediated	mediate	VERB
fnp-3528	1146	48	abca1	abca1	NOUN
fnp-3528	1146	49	/	/	SYM
fnp-3528	1146	50	abcg1	abcg1	NOUN
fnp-3528	1146	51	-	-	PUNCT
fnp-3528	1146	52	dependent	dependent	ADJ
fnp-3528	1146	53	cholesterol	cholesterol	NOUN
fnp-3528	1146	54	efflux	efflux	VERB
fnp-3528	1146	55	from	from	ADP
fnp-3528	1146	56	macrophages	macrophage	NOUN
fnp-3528	1146	57	.	.	PUNCT
fnp-3528	1147	1	life	life	NOUN
fnp-3528	1147	2	sci	sci	PROPN
fnp-3528	1147	3	2018	2018	NUM
fnp-3528	1147	4	,	,	PUNCT
fnp-3528	1147	5	214	214	NUM
fnp-3528	1147	6	,	,	PUNCT
fnp-3528	1147	7	41	41	NUM
fnp-3528	1147	8	-	-	SYM
fnp-3528	1147	9	50	50	NUM
fnp-3528	1147	10	.	.	PUNCT
fnp-3528	1148	1	luo	luo	PROPN
fnp-3528	1148	2	,	,	PUNCT
fnp-3528	1148	3	g.	g.	PROPN
fnp-3528	1148	4	;	;	PUNCT
fnp-3528	1148	5	qian	qian	PROPN
fnp-3528	1148	6	,	,	PUNCT
fnp-3528	1148	7	z.	z.	PROPN
fnp-3528	1148	8	;	;	PUNCT
fnp-3528	1148	9	qiu	qiu	PROPN
fnp-3528	1148	10	,	,	PUNCT
fnp-3528	1148	11	r.	r.	PROPN
fnp-3528	1148	12	;	;	PUNCT
fnp-3528	1148	13	you	you	PRON
fnp-3528	1148	14	,	,	PUNCT
fnp-3528	1148	15	q.	q.	PROPN
fnp-3528	1148	16	;	;	PUNCT
fnp-3528	1148	17	xiang	xiang	PROPN
fnp-3528	1148	18	,	,	PUNCT
fnp-3528	1148	19	h.	h.	PROPN
fnp-3528	1148	20	lipid	lipid	NOUN
fnp-3528	1148	21	reducing	reduce	VERB
fnp-3528	1148	22	activity	activity	NOUN
fnp-3528	1148	23	of	of	ADP
fnp-3528	1148	24	novel	novel	ADJ
fnp-3528	1148	25	cholic	cholic	NOUN
fnp-3528	1148	26	acid	acid	NOUN
fnp-3528	1148	27	(	(	PUNCT
fnp-3528	1148	28	ca	ca	NOUN
fnp-3528	1148	29	)	)	PUNCT
fnp-3528	1148	30	analogs	analog	NOUN
fnp-3528	1148	31	:	:	PUNCT
fnp-3528	1148	32	design	design	NOUN
fnp-3528	1148	33	,	,	PUNCT
fnp-3528	1148	34	synthesis	synthesis	NOUN
fnp-3528	1148	35	and	and	CCONJ
fnp-3528	1148	36	preliminary	preliminary	ADJ
fnp-3528	1148	37	mechanism	mechanism	NOUN
fnp-3528	1148	38	study	study	NOUN
fnp-3528	1148	39	.	.	PUNCT
fnp-3528	1149	1	bioorg	bioorg	PROPN
fnp-3528	1149	2	chem	chem	NOUN
fnp-3528	1149	3	2018	2018	NUM
fnp-3528	1149	4	,	,	PUNCT
fnp-3528	1149	5	80	80	NUM
fnp-3528	1149	6	,	,	PUNCT
fnp-3528	1149	7	396	396	NUM
fnp-3528	1149	8	-	-	SYM
fnp-3528	1149	9	407	407	NUM
fnp-3528	1149	10	.	.	PUNCT
fnp-3528	1150	1	ni	ni	PROPN
fnp-3528	1150	2	,	,	PUNCT
fnp-3528	1150	3	j.	j.	PROPN
fnp-3528	1150	4	;	;	PUNCT
fnp-3528	1150	5	zhou	zhou	PROPN
fnp-3528	1150	6	,	,	PUNCT
fnp-3528	1150	7	l.	l.	PROPN
fnp-3528	1150	8	l.	l.	PROPN
fnp-3528	1150	9	;	;	PUNCT
fnp-3528	1150	10	ding	ding	PROPN
fnp-3528	1150	11	,	,	PUNCT
fnp-3528	1150	12	l.	l.	PROPN
fnp-3528	1150	13	;	;	PUNCT
fnp-3528	1150	14	zhang	zhang	PROPN
fnp-3528	1150	15	,	,	PUNCT
fnp-3528	1150	16	x.	x.	PROPN
fnp-3528	1150	17	q.	q.	PROPN
fnp-3528	1150	18	;	;	PUNCT
fnp-3528	1150	19	zhao	zhao	X
fnp-3528	1150	20	,	,	PUNCT
fnp-3528	1150	21	x.	x.	PROPN
fnp-3528	1150	22	;	;	PUNCT
fnp-3528	1150	23	li	li	PROPN
fnp-3528	1150	24	,	,	PUNCT
fnp-3528	1150	25	h.	h.	PROPN
fnp-3528	1150	26	;	;	PUNCT
fnp-3528	1150	27	cao	cao	PROPN
fnp-3528	1150	28	,	,	PUNCT
fnp-3528	1150	29	h.	h.	PROPN
fnp-3528	1150	30	;	;	PUNCT
fnp-3528	1150	31	liu	liu	PROPN
fnp-3528	1150	32	,	,	PUNCT
fnp-3528	1150	33	s.	s.	PROPN
fnp-3528	1150	34	;	;	PUNCT
fnp-3528	1150	35	wang	wang	PROPN
fnp-3528	1150	36	,	,	PUNCT
fnp-3528	1150	37	z.	z.	PROPN
fnp-3528	1150	38	;	;	PUNCT
fnp-3528	1150	39	ma	ma	PROPN
fnp-3528	1150	40	,	,	PUNCT
fnp-3528	1150	41	r.	r.	PROPN
fnp-3528	1150	42	;	;	PUNCT
fnp-3528	1150	43	wu	wu	PROPN
fnp-3528	1150	44	,	,	PUNCT
fnp-3528	1150	45	j.	j.	PROPN
fnp-3528	1150	46	;	;	PUNCT
fnp-3528	1150	47	feng	feng	PROPN
fnp-3528	1150	48	,	,	PUNCT
fnp-3528	1150	49	j.	j.	PROPN
fnp-3528	1150	50	efatutazone	efatutazone	PROPN
fnp-3528	1150	51	and	and	CCONJ
fnp-3528	1150	52	t0901317	t0901317	NOUN
fnp-3528	1150	53	exert	exert	VERB
fnp-3528	1150	54	synergistically	synergistically	ADV
fnp-3528	1150	55	therapeutic	therapeutic	ADJ
fnp-3528	1150	56	effects	effect	NOUN
fnp-3528	1150	57	in	in	ADP
fnp-3528	1150	58	acquired	acquire	VERB
fnp-3528	1150	59	gefitinib	gefitinib	NOUN
fnp-3528	1150	60	-	-	PUNCT
fnp-3528	1150	61	resistant	resistant	ADJ
fnp-3528	1150	62	lung	lung	NOUN
fnp-3528	1150	63	adenocarcinoma	adenocarcinoma	NOUN
fnp-3528	1150	64	cells	cell	NOUN
fnp-3528	1150	65	.	.	PUNCT
fnp-3528	1151	1	cancer	cancer	NOUN
fnp-3528	1151	2	med	med	PROPN
fnp-3528	1151	3	2018	2018	NUM
fnp-3528	1151	4	,	,	PUNCT
fnp-3528	1151	5	7	7	NUM
fnp-3528	1151	6	,	,	PUNCT
fnp-3528	1151	7	1955	1955	NUM
fnp-3528	1151	8	-	-	SYM
fnp-3528	1151	9	66	66	NUM
fnp-3528	1151	10	.	.	PUNCT
fnp-3528	1152	1	saenz	saenz	PROPN
fnp-3528	1152	2	,	,	PUNCT
fnp-3528	1152	3	j.	j.	PROPN
fnp-3528	1152	4	;	;	PUNCT
fnp-3528	1152	5	alba	alba	PROPN
fnp-3528	1152	6	,	,	PUNCT
fnp-3528	1152	7	g.	g.	PROPN
fnp-3528	1152	8	;	;	PUNCT
fnp-3528	1152	9	reyes	reyes	PROPN
fnp-3528	1152	10	-	-	PUNCT
fnp-3528	1152	11	quiroz	quiroz	PROPN
fnp-3528	1152	12	,	,	PUNCT
fnp-3528	1152	13	m.	m.	PROPN
fnp-3528	1152	14	e.	e.	PROPN
fnp-3528	1152	15	;	;	PUNCT
fnp-3528	1152	16	geniz	geniz	PROPN
fnp-3528	1152	17	,	,	PUNCT
fnp-3528	1152	18	i.	i.	PROPN
fnp-3528	1152	19	;	;	PUNCT
fnp-3528	1152	20	jimenez	jimenez	PROPN
fnp-3528	1152	21	,	,	PUNCT
fnp-3528	1152	22	j.	j.	PROPN
fnp-3528	1152	23	;	;	PUNCT
fnp-3528	1152	24	sobrino	sobrino	PROPN
fnp-3528	1152	25	,	,	PUNCT
fnp-3528	1152	26	f.	f.	PROPN
fnp-3528	1152	27	;	;	PUNCT
fnp-3528	1152	28	santa	santa	PROPN
fnp-3528	1152	29	-	-	PUNCT
fnp-3528	1152	30	maria	maria	PROPN
fnp-3528	1152	31	,	,	PUNCT
fnp-3528	1152	32	c.	c.	PROPN
fnp-3528	1152	33	curcumin	curcumin	PROPN
fnp-3528	1152	34	enhances	enhance	VERB
fnp-3528	1152	35	lxralpha	lxralpha	NOUN
fnp-3528	1152	36	in	in	ADP
fnp-3528	1152	37	an	an	DET
fnp-3528	1152	38	amp	amp	NOUN
fnp-3528	1152	39	-	-	PUNCT
fnp-3528	1152	40	activated	activate	VERB
fnp-3528	1152	41	protein	protein	NOUN
fnp-3528	1152	42	kinase	kinase	NOUN
fnp-3528	1152	43	-	-	PUNCT
fnp-3528	1152	44	dependent	dependent	ADJ
fnp-3528	1152	45	manner	manner	NOUN
fnp-3528	1152	46	in	in	ADP
fnp-3528	1152	47	human	human	ADJ
fnp-3528	1152	48	macrophages	macrophage	NOUN
fnp-3528	1152	49	.	.	PUNCT
fnp-3528	1153	1	j	j	PROPN
fnp-3528	1153	2	nutr	nutr	PROPN
fnp-3528	1153	3	biochem	biochem	PROPN
fnp-3528	1153	4	2018	2018	NUM
fnp-3528	1153	5	,	,	PUNCT
fnp-3528	1153	6	54	54	NUM
fnp-3528	1153	7	,	,	PUNCT
fnp-3528	1153	8	48	48	NUM
fnp-3528	1153	9	-	-	SYM
fnp-3528	1153	10	56	56	NUM
fnp-3528	1153	11	.	.	PUNCT
fnp-3528	1154	1	saenz	saenz	PROPN
fnp-3528	1154	2	,	,	PUNCT
fnp-3528	1154	3	j.	j.	PROPN
fnp-3528	1154	4	;	;	PUNCT
fnp-3528	1154	5	santa	santa	PROPN
fnp-3528	1154	6	-	-	PUNCT
fnp-3528	1154	7	maria	maria	PROPN
fnp-3528	1154	8	,	,	PUNCT
fnp-3528	1154	9	c.	c.	PROPN
fnp-3528	1154	10	;	;	PUNCT
fnp-3528	1154	11	reyes	reyes	PROPN
fnp-3528	1154	12	-	-	PUNCT
fnp-3528	1154	13	quiroz	quiroz	PROPN
fnp-3528	1154	14	,	,	PUNCT
fnp-3528	1154	15	m.	m.	PROPN
fnp-3528	1154	16	e.	e.	PROPN
fnp-3528	1154	17	;	;	PUNCT
fnp-3528	1154	18	geniz	geniz	PROPN
fnp-3528	1154	19	,	,	PUNCT
fnp-3528	1154	20	i.	i.	PROPN
fnp-3528	1154	21	;	;	PUNCT
fnp-3528	1154	22	jimenez	jimenez	PROPN
fnp-3528	1154	23	,	,	PUNCT
fnp-3528	1154	24	j.	j.	PROPN
fnp-3528	1154	25	;	;	PUNCT
fnp-3528	1154	26	sobrino	sobrino	PROPN
fnp-3528	1154	27	,	,	PUNCT
fnp-3528	1154	28	f.	f.	PROPN
fnp-3528	1154	29	;	;	PUNCT
fnp-3528	1154	30	alba	alba	PROPN
fnp-3528	1154	31	,	,	PUNCT
fnp-3528	1154	32	g.	g.	PROPN
fnp-3528	1154	33	grapefruit	grapefruit	PROPN
fnp-3528	1154	34	flavonoid	flavonoid	PROPN
fnp-3528	1154	35	naringenin	naringenin	PROPN
fnp-3528	1154	36	regulates	regulate	VERB
fnp-3528	1154	37	the	the	DET
fnp-3528	1154	38	expression	expression	NOUN
fnp-3528	1154	39	of	of	ADP
fnp-3528	1154	40	lxralpha	lxralpha	NOUN
fnp-3528	1154	41	in	in	ADP
fnp-3528	1154	42	thp-1	thp-1	PUNCT
fnp-3528	1154	43	macrophages	macrophage	NOUN
fnp-3528	1154	44	by	by	ADP
fnp-3528	1154	45	modulating	modulate	VERB
fnp-3528	1154	46	amp	amp	NOUN
fnp-3528	1154	47	-	-	PUNCT
fnp-3528	1154	48	activated	activate	VERB
fnp-3528	1154	49	protein	protein	NOUN
fnp-3528	1154	50	kinase	kinase	NOUN
fnp-3528	1154	51	.	.	PUNCT
fnp-3528	1155	1	mol	mol	ADP
fnp-3528	1155	2	pharm	pharm	PROPN
fnp-3528	1155	3	2018	2018	NUM
fnp-3528	1155	4	,	,	PUNCT
fnp-3528	1155	5	15	15	NUM
fnp-3528	1155	6	,	,	PUNCT
fnp-3528	1155	7	1735	1735	NUM
fnp-3528	1155	8	-	-	SYM
fnp-3528	1155	9	45	45	NUM
fnp-3528	1155	10	.	.	PUNCT
fnp-3528	1156	1	lei	lei	PROPN
fnp-3528	1156	2	,	,	PUNCT
fnp-3528	1156	3	c.	c.	PROPN
fnp-3528	1156	4	;	;	PUNCT
fnp-3528	1156	5	lin	lin	PROPN
fnp-3528	1156	6	,	,	PUNCT
fnp-3528	1156	7	r.	r.	PROPN
fnp-3528	1156	8	;	;	PUNCT
fnp-3528	1156	9	wang	wang	PROPN
fnp-3528	1156	10	,	,	PUNCT
fnp-3528	1156	11	j.	j.	PROPN
fnp-3528	1156	12	;	;	PUNCT
fnp-3528	1156	13	tao	tao	PROPN
fnp-3528	1156	14	,	,	PUNCT
fnp-3528	1156	15	l.	l.	PROPN
fnp-3528	1156	16	;	;	PUNCT
fnp-3528	1156	17	fu	fu	PROPN
fnp-3528	1156	18	,	,	PUNCT
fnp-3528	1156	19	x.	x.	PROPN
fnp-3528	1156	20	;	;	PUNCT
fnp-3528	1156	21	qiu	qiu	PROPN
fnp-3528	1156	22	,	,	PUNCT
fnp-3528	1156	23	y.	y.	PROPN
fnp-3528	1156	24	;	;	PUNCT
fnp-3528	1156	25	lei	lei	PROPN
fnp-3528	1156	26	,	,	PUNCT
fnp-3528	1156	27	b.	b.	PROPN
fnp-3528	1156	28	amelioration	amelioration	NOUN
fnp-3528	1156	29	of	of	ADP
fnp-3528	1156	30	amyloid	amyloid	NOUN
fnp-3528	1156	31	beta	beta	NOUN
fnp-3528	1156	32	-	-	PUNCT
fnp-3528	1156	33	induced	induce	VERB
fnp-3528	1156	34	retinal	retinal	ADJ
fnp-3528	1156	35	inflammatory	inflammatory	ADJ
fnp-3528	1156	36	responses	response	NOUN
fnp-3528	1156	37	by	by	ADP
fnp-3528	1156	38	a	a	DET
fnp-3528	1156	39	lxr	lxr	NOUN
fnp-3528	1156	40	agonist	agonist	NOUN
fnp-3528	1156	41	to901317	to901317	NOUN
fnp-3528	1156	42	is	be	AUX
fnp-3528	1156	43	associated	associate	VERB
fnp-3528	1156	44	with	with	ADP
fnp-3528	1156	45	inhibition	inhibition	NOUN
fnp-3528	1156	46	of	of	ADP
fnp-3528	1156	47	the	the	DET
fnp-3528	1156	48	nf	nf	ADJ
fnp-3528	1156	49	-	-	PUNCT
fnp-3528	1156	50	kappab	kappab	NOUN
fnp-3528	1156	51	signaling	signaling	ADJ
fnp-3528	1156	52	and	and	CCONJ
fnp-3528	1156	53	nlrp3	nlrp3	ADJ
fnp-3528	1156	54	inflammasome	inflammasome	NOUN
fnp-3528	1156	55	.	.	PUNCT
fnp-3528	1157	1	neurosci	neurosci	PROPN
fnp-3528	1157	2	2017	2017	NUM
fnp-3528	1157	3	,	,	PUNCT
fnp-3528	1157	4	360	360	NUM
fnp-3528	1157	5	,	,	PUNCT
fnp-3528	1157	6	48	48	NUM
fnp-3528	1157	7	-	-	SYM
fnp-3528	1157	8	60	60	NUM
fnp-3528	1157	9	.	.	PUNCT
fnp-3528	1158	1	fernandez	fernandez	NOUN
fnp-3528	1158	2	-	-	PUNCT
fnp-3528	1158	3	suarez	suarez	PROPN
fnp-3528	1158	4	,	,	PUNCT
fnp-3528	1158	5	m.	m.	PROPN
fnp-3528	1158	6	e.	e.	PROPN
fnp-3528	1158	7	;	;	PUNCT
fnp-3528	1158	8	escola	escola	PROPN
fnp-3528	1158	9	-	-	PUNCT
fnp-3528	1158	10	gil	gil	PROPN
fnp-3528	1158	11	,	,	PUNCT
fnp-3528	1158	12	j.	j.	PROPN
fnp-3528	1158	13	c.	c.	PROPN
fnp-3528	1158	14	;	;	PUNCT
fnp-3528	1158	15	pastor	pastor	NOUN
fnp-3528	1158	16	,	,	PUNCT
fnp-3528	1158	17	o.	o.	PROPN
fnp-3528	1158	18	;	;	PUNCT
fnp-3528	1158	19	davalos	davalos	PROPN
fnp-3528	1158	20	,	,	PUNCT
fnp-3528	1158	21	a.	a.	PROPN
fnp-3528	1158	22	;	;	PUNCT
fnp-3528	1158	23	blanco	blanco	PROPN
fnp-3528	1158	24	-	-	PUNCT
fnp-3528	1158	25	vaca	vaca	PROPN
fnp-3528	1158	26	,	,	PUNCT
fnp-3528	1158	27	f.	f.	PROPN
fnp-3528	1158	28	;	;	PUNCT
fnp-3528	1158	29	lasuncion	lasuncion	NOUN
fnp-3528	1158	30	,	,	PUNCT
fnp-3528	1158	31	m.	m.	NOUN
fnp-3528	1158	32	a.	a.	PROPN
fnp-3528	1158	33	;	;	PUNCT
fnp-3528	1158	34	martinez	martinez	PROPN
fnp-3528	1158	35	-	-	PUNCT
fnp-3528	1158	36	botas	botas	PROPN
fnp-3528	1158	37	,	,	PUNCT
fnp-3528	1158	38	j.	j.	PROPN
fnp-3528	1158	39	;	;	PUNCT
fnp-3528	1158	40	gomez	gomez	PROPN
fnp-3528	1158	41	-	-	PUNCT
fnp-3528	1158	42	coronado	coronado	PROPN
fnp-3528	1158	43	,	,	PUNCT
fnp-3528	1158	44	d.	d.	PROPN
fnp-3528	1158	45	clinically	clinically	ADV
fnp-3528	1158	46	used	use	VERB
fnp-3528	1158	47	selective	selective	ADJ
fnp-3528	1158	48	estrogen	estrogen	NOUN
fnp-3528	1158	49	receptor	receptor	NOUN
fnp-3528	1158	50	modulators	modulator	NOUN
fnp-3528	1158	51	affect	affect	VERB
fnp-3528	1158	52	different	different	ADJ
fnp-3528	1158	53	steps	step	NOUN
fnp-3528	1158	54	of	of	ADP
fnp-3528	1158	55	macrophage	macrophage	ADJ
fnp-3528	1158	56	-	-	PUNCT
fnp-3528	1158	57	specific	specific	ADJ
fnp-3528	1158	58	reverse	reverse	ADJ
fnp-3528	1158	59	cholesterol	cholesterol	NOUN
fnp-3528	1158	60	transport	transport	NOUN
fnp-3528	1158	61	.	.	PUNCT
fnp-3528	1159	1	sci	sci	PROPN
fnp-3528	1159	2	rep	rep	PROPN
fnp-3528	1159	3	2016	2016	NUM
fnp-3528	1159	4	,	,	PUNCT
fnp-3528	1159	5	6	6	NUM
fnp-3528	1159	6	,	,	PUNCT
fnp-3528	1159	7	32105	32105	NUM
fnp-3528	1159	8	.	.	PUNCT
fnp-3528	1160	1	hoang	hoang	PROPN
fnp-3528	1160	2	,	,	PUNCT
fnp-3528	1160	3	m.	m.	PROPN
fnp-3528	1160	4	h.	h.	PROPN
fnp-3528	1160	5	;	;	PUNCT
fnp-3528	1160	6	jia	jia	PROPN
fnp-3528	1160	7	,	,	PUNCT
fnp-3528	1160	8	y.	y.	PROPN
fnp-3528	1160	9	;	;	PUNCT
fnp-3528	1160	10	jun	jun	PROPN
fnp-3528	1160	11	,	,	PUNCT
fnp-3528	1160	12	h.	h.	PROPN
fnp-3528	1160	13	j.	j.	PROPN
fnp-3528	1160	14	;	;	PUNCT
fnp-3528	1160	15	lee	lee	PROPN
fnp-3528	1160	16	,	,	PUNCT
fnp-3528	1160	17	j.	j.	PROPN
fnp-3528	1160	18	h.	h.	PROPN
fnp-3528	1160	19	;	;	PUNCT
fnp-3528	1160	20	lee	lee	PROPN
fnp-3528	1160	21	,	,	PUNCT
fnp-3528	1160	22	d.	d.	PROPN
fnp-3528	1160	23	h.	h.	PROPN
fnp-3528	1160	24	;	;	PUNCT
fnp-3528	1160	25	hwang	hwang	PROPN
fnp-3528	1160	26	,	,	PUNCT
fnp-3528	1160	27	b.	b.	PROPN
fnp-3528	1160	28	y.	y.	PROPN
fnp-3528	1160	29	;	;	PUNCT
fnp-3528	1160	30	kim	kim	PROPN
fnp-3528	1160	31	,	,	PUNCT
fnp-3528	1160	32	w.	w.	PROPN
fnp-3528	1160	33	j.	j.	PROPN
fnp-3528	1160	34	;	;	PUNCT
fnp-3528	1160	35	lee	lee	PROPN
fnp-3528	1160	36	,	,	PUNCT
fnp-3528	1160	37	h.	h.	PROPN
fnp-3528	1160	38	j.	j.	PROPN
fnp-3528	1160	39	;	;	PUNCT
fnp-3528	1160	40	lee	lee	PROPN
fnp-3528	1160	41	,	,	PUNCT
fnp-3528	1160	42	s.	s.	PROPN
fnp-3528	1160	43	j.	j.	PROPN
fnp-3528	1160	44	ethyl	ethyl	PROPN
fnp-3528	1160	45	2,4,6	2,4,6	PROPN
fnp-3528	1160	46	-	-	PUNCT
fnp-3528	1160	47	trihydroxybenzoate	trihydroxybenzoate	NOUN
fnp-3528	1160	48	is	be	AUX
fnp-3528	1160	49	an	an	DET
fnp-3528	1160	50	agonistic	agonistic	ADJ
fnp-3528	1160	51	ligand	ligand	NOUN
fnp-3528	1160	52	for	for	ADP
fnp-3528	1160	53	liver	liver	NOUN
fnp-3528	1160	54	x	x	NOUN
fnp-3528	1160	55	receptor	receptor	NOUN
fnp-3528	1160	56	that	that	PRON
fnp-3528	1160	57	induces	induce	VERB
fnp-3528	1160	58	cholesterol	cholesterol	NOUN
fnp-3528	1160	59	efflux	efflux	NOUN
fnp-3528	1160	60	from	from	ADP
fnp-3528	1160	61	macrophages	macrophage	NOUN
fnp-3528	1160	62	without	without	ADP
fnp-3528	1160	63	affecting	affect	VERB
fnp-3528	1160	64	lipid	lipid	ADJ
fnp-3528	1160	65	accumulation	accumulation	NOUN
fnp-3528	1160	66	in	in	ADP
fnp-3528	1160	67	hepg2	hepg2	NOUN
fnp-3528	1160	68	cells	cell	NOUN
fnp-3528	1160	69	.	.	PUNCT
fnp-3528	1161	1	bioorg	bioorg	PROPN
fnp-3528	1161	2	med	med	PROPN
fnp-3528	1161	3	chem	chem	NOUN
fnp-3528	1161	4	lett	lett	PROPN
fnp-3528	1161	5	2012	2012	NUM
fnp-3528	1161	6	,	,	PUNCT
fnp-3528	1161	7	22	22	NUM
fnp-3528	1161	8	,	,	PUNCT
fnp-3528	1161	9	4094	4094	NUM
fnp-3528	1161	10	-	-	SYM
fnp-3528	1161	11	9	9	NUM
fnp-3528	1161	12	.	.	PUNCT
fnp-3528	1162	1	maejima	maejima	PROPN
fnp-3528	1162	2	,	,	PUNCT
fnp-3528	1162	3	t.	t.	PROPN
fnp-3528	1162	4	;	;	PUNCT
fnp-3528	1162	5	sugano	sugano	VERB
fnp-3528	1162	6	,	,	PUNCT
fnp-3528	1162	7	t.	t.	PROPN
fnp-3528	1162	8	;	;	PUNCT
fnp-3528	1162	9	yamazaki	yamazaki	PROPN
fnp-3528	1162	10	,	,	PUNCT
fnp-3528	1162	11	h.	h.	PROPN
fnp-3528	1162	12	;	;	PUNCT
fnp-3528	1162	13	yoshinaka	yoshinaka	PROPN
fnp-3528	1162	14	,	,	PUNCT
fnp-3528	1162	15	y.	y.	PROPN
fnp-3528	1162	16	;	;	PUNCT
fnp-3528	1162	17	doi	doi	PROPN
fnp-3528	1162	18	,	,	PUNCT
fnp-3528	1162	19	t.	t.	PROPN
fnp-3528	1162	20	;	;	PUNCT
fnp-3528	1162	21	tanabe	tanabe	PROPN
fnp-3528	1162	22	,	,	PUNCT
fnp-3528	1162	23	s.	s.	PROPN
fnp-3528	1162	24	;	;	PUNCT
fnp-3528	1162	25	nishimaki	nishimaki	NOUN
fnp-3528	1162	26	-	-	PUNCT
fnp-3528	1162	27	mogami	mogami	NOUN
fnp-3528	1162	28	,	,	PUNCT
fnp-3528	1162	29	t.	t.	NOUN
fnp-3528	1162	30	pitavastatin	pitavastatin	NOUN
fnp-3528	1162	31	increases	increase	VERB
fnp-3528	1162	32	abca1	abca1	NOUN
fnp-3528	1162	33	expression	expression	NOUN
fnp-3528	1162	34	by	by	ADP
fnp-3528	1162	35	dual	dual	ADJ
fnp-3528	1162	36	mechanisms	mechanism	NOUN
fnp-3528	1162	37	:	:	PUNCT
fnp-3528	1162	38	srebp2	srebp2	NOUN
fnp-3528	1162	39	-	-	PUNCT
fnp-3528	1162	40	driven	drive	VERB
fnp-3528	1162	41	transcriptional	transcriptional	ADJ
fnp-3528	1162	42	activation	activation	NOUN
fnp-3528	1162	43	and	and	CCONJ
fnp-3528	1162	44	pparalpha	pparalpha	ADJ
fnp-3528	1162	45	-	-	ADJ
fnp-3528	1162	46	dependent	dependent	ADJ
fnp-3528	1162	47	protein	protein	NOUN
fnp-3528	1162	48	stabilization	stabilization	NOUN
fnp-3528	1162	49	but	but	CCONJ
fnp-3528	1162	50	without	without	ADP
fnp-3528	1162	51	activating	activate	VERB
fnp-3528	1162	52	lxr	lxr	NOUN
fnp-3528	1162	53	in	in	ADP
fnp-3528	1162	54	rat	rat	NOUN
fnp-3528	1162	55	hepatoma	hepatoma	ADJ
fnp-3528	1162	56	mcarh7777	mcarh7777	PROPN
fnp-3528	1162	57	cells	cell	NOUN
fnp-3528	1162	58	.	.	PUNCT
fnp-3528	1163	1	j	j	PROPN
fnp-3528	1163	2	pharmacol	pharmacol	PROPN
fnp-3528	1163	3	sci	sci	PROPN
fnp-3528	1163	4	2011	2011	NUM
fnp-3528	1163	5	,	,	PUNCT
fnp-3528	1163	6	116	116	NUM
fnp-3528	1163	7	,	,	PUNCT
fnp-3528	1163	8	107	107	NUM
fnp-3528	1163	9	-	-	SYM
fnp-3528	1163	10	15	15	NUM
fnp-3528	1163	11	.	.	PUNCT
fnp-3528	1164	1	fitz	fitz	PROPN
fnp-3528	1164	2	,	,	PUNCT
fnp-3528	1164	3	n.	n.	PROPN
fnp-3528	1164	4	f.	f.	PROPN
fnp-3528	1164	5	;	;	PUNCT
fnp-3528	1164	6	cronican	cronican	PROPN
fnp-3528	1164	7	,	,	PUNCT
fnp-3528	1164	8	a.	a.	PROPN
fnp-3528	1164	9	;	;	PUNCT
fnp-3528	1164	10	pham	pham	PROPN
fnp-3528	1164	11	,	,	PUNCT
fnp-3528	1164	12	t.	t.	PROPN
fnp-3528	1164	13	;	;	PUNCT
fnp-3528	1164	14	fogg	fogg	PROPN
fnp-3528	1164	15	,	,	PUNCT
fnp-3528	1164	16	a.	a.	NOUN
fnp-3528	1164	17	;	;	PUNCT
fnp-3528	1164	18	fauq	fauq	NOUN
fnp-3528	1164	19	,	,	PUNCT
fnp-3528	1164	20	a.	a.	PROPN
fnp-3528	1164	21	h.	h.	PROPN
fnp-3528	1164	22	;	;	PUNCT
fnp-3528	1164	23	chapman	chapman	PROPN
fnp-3528	1164	24	,	,	PUNCT
fnp-3528	1164	25	r.	r.	PROPN
fnp-3528	1164	26	;	;	PUNCT
fnp-3528	1164	27	lefterov	lefterov	PROPN
fnp-3528	1164	28	,	,	PUNCT
fnp-3528	1164	29	i.	i.	NOUN
fnp-3528	1164	30	;	;	PUNCT
fnp-3528	1164	31	koldamova	koldamova	PROPN
fnp-3528	1164	32	,	,	PUNCT
fnp-3528	1164	33	r.	r.	PROPN
fnp-3528	1164	34	liver	liver	NOUN
fnp-3528	1164	35	x	x	ADP
fnp-3528	1164	36	receptor	receptor	NOUN
fnp-3528	1164	37	agonist	agonist	NOUN
fnp-3528	1164	38	treatment	treatment	NOUN
fnp-3528	1164	39	ameliorates	ameliorate	VERB
fnp-3528	1164	40	amyloid	amyloid	NOUN
fnp-3528	1164	41	pathology	pathology	NOUN
fnp-3528	1164	42	and	and	CCONJ
fnp-3528	1164	43	memory	memory	NOUN
fnp-3528	1164	44	deficits	deficit	NOUN
fnp-3528	1164	45	caused	cause	VERB
fnp-3528	1164	46	by	by	ADP
fnp-3528	1164	47	high	high	ADJ
fnp-3528	1164	48	-	-	PUNCT
fnp-3528	1164	49	fat	fat	NOUN
fnp-3528	1164	50	diet	diet	NOUN
fnp-3528	1164	51	in	in	ADP
fnp-3528	1164	52	app23	app23	PROPN
fnp-3528	1164	53	mice	mouse	NOUN
fnp-3528	1164	54	.	.	PUNCT
fnp-3528	1165	1	j	j	PROPN
fnp-3528	1165	2	neurosci	neurosci	PROPN
fnp-3528	1165	3	2010	2010	NUM
fnp-3528	1165	4	,	,	PUNCT
fnp-3528	1165	5	30	30	NUM
fnp-3528	1165	6	,	,	PUNCT
fnp-3528	1165	7	6862	6862	NUM
fnp-3528	1165	8	-	-	SYM
fnp-3528	1165	9	72	72	NUM
fnp-3528	1165	10	.	.	PUNCT
fnp-3528	1166	1	fukumoto	fukumoto	PROPN
fnp-3528	1166	2	,	,	PUNCT
fnp-3528	1166	3	h.	h.	PROPN
fnp-3528	1166	4	;	;	PUNCT
fnp-3528	1166	5	deng	deng	PROPN
fnp-3528	1166	6	,	,	PUNCT
fnp-3528	1166	7	a.	a.	NOUN
fnp-3528	1166	8	;	;	PUNCT
fnp-3528	1166	9	irizarry	irizarry	NOUN
fnp-3528	1166	10	,	,	PUNCT
fnp-3528	1166	11	m.	m.	NOUN
fnp-3528	1166	12	c.	c.	PROPN
fnp-3528	1166	13	;	;	PUNCT
fnp-3528	1166	14	fitzgerald	fitzgerald	PROPN
fnp-3528	1166	15	,	,	PUNCT
fnp-3528	1166	16	m.	m.	PROPN
fnp-3528	1166	17	l.	l.	PROPN
fnp-3528	1166	18	;	;	PUNCT
fnp-3528	1166	19	rebeck	rebeck	PROPN
fnp-3528	1166	20	,	,	PUNCT
fnp-3528	1166	21	g.	g.	PROPN
fnp-3528	1166	22	w.	w.	PROPN
fnp-3528	1166	23	induction	induction	NOUN
fnp-3528	1166	24	of	of	ADP
fnp-3528	1166	25	the	the	DET
fnp-3528	1166	26	cholesterol	cholesterol	NOUN
fnp-3528	1166	27	transporter	transporter	NOUN
fnp-3528	1166	28	abca1	abca1	NOUN
fnp-3528	1166	29	in	in	ADP
fnp-3528	1166	30	central	central	ADJ
fnp-3528	1166	31	nervous	nervous	ADJ
fnp-3528	1166	32	system	system	NOUN
fnp-3528	1166	33	cells	cell	NOUN
fnp-3528	1166	34	by	by	ADP
fnp-3528	1166	35	liver	liver	NOUN
fnp-3528	1166	36	x	x	SYM
fnp-3528	1166	37	receptor	receptor	NOUN
fnp-3528	1166	38	agonists	agonist	NOUN
fnp-3528	1166	39	increases	increase	NOUN
fnp-3528	1166	40	secreted	secrete	VERB
fnp-3528	1166	41	abeta	abeta	NOUN
fnp-3528	1166	42	levels	level	NOUN
fnp-3528	1166	43	.	.	PUNCT
fnp-3528	1167	1	j	j	PROPN
fnp-3528	1167	2	biol	biol	PROPN
fnp-3528	1167	3	chem	chem	NOUN
fnp-3528	1167	4	2002	2002	NUM
fnp-3528	1167	5	,	,	PUNCT
fnp-3528	1167	6	277	277	NUM
fnp-3528	1167	7	,	,	PUNCT
fnp-3528	1167	8	48508	48508	NUM
fnp-3528	1167	9	-	-	SYM
fnp-3528	1167	10	13	13	NUM
fnp-3528	1167	11	.	.	PUNCT
fnp-3528	1168	1	van	van	PROPN
fnp-3528	1168	2	riel	riel	PROPN
fnp-3528	1168	3	,	,	PUNCT
fnp-3528	1168	4	n.	n.	PROPN
fnp-3528	1168	5	a.	a.	PROPN
fnp-3528	1168	6	w.	w.	PROPN
fnp-3528	1168	7	;	;	PUNCT
fnp-3528	1168	8	tiemann	tiemann	PROPN
fnp-3528	1168	9	,	,	PUNCT
fnp-3528	1168	10	c.	c.	PROPN
fnp-3528	1168	11	a.	a.	PROPN
fnp-3528	1168	12	;	;	PUNCT
fnp-3528	1168	13	hilbers	hilber	NOUN
fnp-3528	1168	14	,	,	PUNCT
fnp-3528	1168	15	p.	p.	NOUN
fnp-3528	1168	16	a.	a.	NOUN
fnp-3528	1168	17	j.	j.	PROPN
fnp-3528	1168	18	;	;	PUNCT
fnp-3528	1168	19	groen	groen	PROPN
fnp-3528	1168	20	,	,	PUNCT
fnp-3528	1168	21	a.	a.	PROPN
fnp-3528	1168	22	k.	k.	PROPN
fnp-3528	1168	23	metabolic	metabolic	PROPN
fnp-3528	1168	24	modeling	modeling	NOUN
fnp-3528	1168	25	combined	combine	VERB
fnp-3528	1168	26	with	with	ADP
fnp-3528	1168	27	machine	machine	NOUN
fnp-3528	1168	28	learning	learn	VERB
fnp-3528	1168	29	integrates	integrate	VERB
fnp-3528	1168	30	longitudinal	longitudinal	ADJ
fnp-3528	1168	31	data	datum	NOUN
fnp-3528	1168	32	and	and	CCONJ
fnp-3528	1168	33	identifies	identify	VERB
fnp-3528	1168	34	the	the	DET
fnp-3528	1168	35	origin	origin	NOUN
fnp-3528	1168	36	of	of	ADP
fnp-3528	1168	37	lxr	lxr	NOUN
fnp-3528	1168	38	-	-	PUNCT
fnp-3528	1168	39	induced	induce	VERB
fnp-3528	1168	40	hepatic	hepatic	ADJ
fnp-3528	1168	41	steatosis	steatosis	NOUN
fnp-3528	1168	42	.	.	PUNCT
fnp-3528	1169	1	front	front	ADJ
fnp-3528	1169	2	bioeng	bioeng	PROPN
fnp-3528	1169	3	biotechnol	biotechnol	NOUN
fnp-3528	1169	4	2020	2020	NUM
fnp-3528	1169	5	,	,	PUNCT
fnp-3528	1169	6	8	8	NUM
fnp-3528	1169	7	,	,	PUNCT
fnp-3528	1169	8	536957	536957	NUM
fnp-3528	1169	9	.	.	PUNCT
fnp-3528	1170	1	chisholm	chisholm	PROPN
fnp-3528	1170	2	,	,	PUNCT
fnp-3528	1170	3	j.	j.	PROPN
fnp-3528	1170	4	w.	w.	PROPN
fnp-3528	1170	5	;	;	PUNCT
fnp-3528	1170	6	hong	hong	PROPN
fnp-3528	1170	7	,	,	PUNCT
fnp-3528	1170	8	j.	j.	PROPN
fnp-3528	1170	9	;	;	PUNCT
fnp-3528	1170	10	mills	mill	NOUN
fnp-3528	1170	11	,	,	PUNCT
fnp-3528	1170	12	s.	s.	PROPN
fnp-3528	1170	13	a.	a.	PROPN
fnp-3528	1170	14	;	;	PUNCT
fnp-3528	1170	15	lawn	lawn	NOUN
fnp-3528	1170	16	,	,	PUNCT
fnp-3528	1170	17	r.	r.	PROPN
fnp-3528	1170	18	m.	m.	PROPN
fnp-3528	1170	19	the	the	DET
fnp-3528	1170	20	lxr	lxr	PROPN
fnp-3528	1170	21	ligand	ligand	NOUN
fnp-3528	1170	22	t0901317	t0901317	NOUN
fnp-3528	1170	23	induces	induce	VERB
fnp-3528	1170	24	severe	severe	ADJ
fnp-3528	1170	25	lipogenesis	lipogenesis	NOUN
fnp-3528	1170	26	in	in	ADP
fnp-3528	1170	27	the	the	DET
fnp-3528	1170	28	db	db	PROPN
fnp-3528	1170	29	/	/	SYM
fnp-3528	1170	30	db	db	PROPN
fnp-3528	1170	31	diabetic	diabetic	ADJ
fnp-3528	1170	32	mouse	mouse	NOUN
fnp-3528	1170	33	.	.	PUNCT
fnp-3528	1171	1	j	j	PROPN
fnp-3528	1171	2	lipid	lipid	PROPN
fnp-3528	1171	3	res	re	NOUN
fnp-3528	1171	4	2003	2003	NUM
fnp-3528	1171	5	,	,	PUNCT
fnp-3528	1171	6	44	44	NUM
fnp-3528	1171	7	,	,	PUNCT
fnp-3528	1171	8	2039	2039	NUM
fnp-3528	1171	9	-	-	SYM
fnp-3528	1171	10	48	48	NUM
fnp-3528	1171	11	.	.	PUNCT
fnp-3528	1172	1	liang	liang	PROPN
fnp-3528	1172	2	,	,	PUNCT
fnp-3528	1172	3	z.	z.	PROPN
fnp-3528	1172	4	;	;	PUNCT
fnp-3528	1172	5	gu	gu	PROPN
fnp-3528	1172	6	,	,	PUNCT
fnp-3528	1172	7	t.	t.	PROPN
fnp-3528	1172	8	;	;	PUNCT
fnp-3528	1172	9	wang	wang	PROPN
fnp-3528	1172	10	,	,	PUNCT
fnp-3528	1172	11	j.	j.	PROPN
fnp-3528	1172	12	;	;	PUNCT
fnp-3528	1172	13	she	she	PRON
fnp-3528	1172	14	,	,	PUNCT
fnp-3528	1172	15	j.	j.	PROPN
fnp-3528	1172	16	;	;	PUNCT
fnp-3528	1172	17	ye	ye	PROPN
fnp-3528	1172	18	,	,	PUNCT
fnp-3528	1172	19	y.	y.	PROPN
fnp-3528	1172	20	;	;	PUNCT
fnp-3528	1172	21	cao	cao	PROPN
fnp-3528	1172	22	,	,	PUNCT
fnp-3528	1172	23	w.	w.	PROPN
fnp-3528	1172	24	;	;	PUNCT
fnp-3528	1172	25	luo	luo	PROPN
fnp-3528	1172	26	,	,	PUNCT
fnp-3528	1172	27	x.	x.	PROPN
fnp-3528	1172	28	;	;	PUNCT
fnp-3528	1172	29	xiao	xiao	PROPN
fnp-3528	1172	30	,	,	PUNCT
fnp-3528	1172	31	j.	j.	PROPN
fnp-3528	1172	32	;	;	PUNCT
fnp-3528	1172	33	liu	liu	PROPN
fnp-3528	1172	34	,	,	PUNCT
fnp-3528	1172	35	y.	y.	PROPN
fnp-3528	1172	36	;	;	PUNCT
fnp-3528	1172	37	tang	tang	PROPN
fnp-3528	1172	38	,	,	PUNCT
fnp-3528	1172	39	l.	l.	PROPN
fnp-3528	1172	40	;	;	PUNCT
fnp-3528	1172	41	zhou	zhou	PROPN
fnp-3528	1172	42	,	,	PUNCT
fnp-3528	1172	43	x.	x.	NOUN
fnp-3528	1172	44	chromene	chromene	PROPN
fnp-3528	1172	45	and	and	CCONJ
fnp-3528	1172	46	chromone	chromone	NOUN
fnp-3528	1172	47	derivatives	derivative	NOUN
fnp-3528	1172	48	as	as	ADP
fnp-3528	1172	49	liver	liver	NOUN
fnp-3528	1172	50	x	x	NOUN
fnp-3528	1172	51	receptors	receptor	NOUN
fnp-3528	1172	52	modulators	modulator	NOUN
fnp-3528	1172	53	from	from	ADP
fnp-3528	1172	54	a	a	DET
fnp-3528	1172	55	marine	marine	ADJ
fnp-3528	1172	56	-	-	PUNCT
fnp-3528	1172	57	derived	derive	VERB
fnp-3528	1172	58	pestalotiopsis	pestalotiopsis	NOUN
fnp-3528	1172	59	neglecta	neglecta	ADJ
fnp-3528	1172	60	fungus	fungus	PROPN
fnp-3528	1172	61	.	.	PUNCT
fnp-3528	1173	1	bioorg	bioorg	PROPN
fnp-3528	1173	2	chem	chem	NOUN
fnp-3528	1173	3	2021	2021	NUM
fnp-3528	1173	4	,	,	PUNCT
fnp-3528	1173	5	112	112	NUM
fnp-3528	1173	6	,	,	PUNCT
fnp-3528	1173	7	104927	104927	NUM
fnp-3528	1173	8	.	.	PUNCT
fnp-3528	1174	1	wang	wang	PROPN
fnp-3528	1174	2	,	,	PUNCT
fnp-3528	1174	3	j.	j.	PROPN
fnp-3528	1174	4	;	;	PUNCT
fnp-3528	1174	5	liang	liang	PROPN
fnp-3528	1174	6	,	,	PUNCT
fnp-3528	1174	7	z.	z.	PROPN
fnp-3528	1174	8	;	;	PUNCT
fnp-3528	1174	9	li	li	PROPN
fnp-3528	1174	10	,	,	PUNCT
fnp-3528	1174	11	k.	k.	PROPN
fnp-3528	1174	12	;	;	PUNCT
fnp-3528	1174	13	yang	yang	PROPN
fnp-3528	1174	14	,	,	PUNCT
fnp-3528	1174	15	b.	b.	PROPN
fnp-3528	1174	16	;	;	PUNCT
fnp-3528	1174	17	liu	liu	PROPN
fnp-3528	1174	18	,	,	PUNCT
fnp-3528	1174	19	y.	y.	PROPN
fnp-3528	1174	20	;	;	PUNCT
fnp-3528	1174	21	fang	fang	X
fnp-3528	1174	22	,	,	PUNCT
fnp-3528	1174	23	w.	w.	PROPN
fnp-3528	1174	24	;	;	PUNCT
fnp-3528	1174	25	tang	tang	PROPN
fnp-3528	1174	26	,	,	PUNCT
fnp-3528	1174	27	l.	l.	PROPN
fnp-3528	1174	28	;	;	PUNCT
fnp-3528	1174	29	zhou	zhou	PROPN
fnp-3528	1174	30	,	,	PUNCT
fnp-3528	1174	31	x.	x.	PROPN
fnp-3528	1174	32	ene	ene	PROPN
fnp-3528	1174	33	-	-	PUNCT
fnp-3528	1174	34	yne	yne	PROPN
fnp-3528	1174	35	hydroquinones	hydroquinone	NOUN
fnp-3528	1174	36	from	from	ADP
fnp-3528	1174	37	a	a	DET
fnp-3528	1174	38	marine	marine	ADJ
fnp-3528	1174	39	-	-	PUNCT
fnp-3528	1174	40	derived	derive	VERB
fnp-3528	1174	41	strain	strain	NOUN
fnp-3528	1174	42	of	of	ADP
fnp-3528	1174	43	the	the	DET
fnp-3528	1174	44	fungus	fungus	NOUN
fnp-3528	1174	45	pestalotiopsis	pestalotiopsis	NOUN
fnp-3528	1174	46	neglecta	neglecta	ADV
fnp-3528	1174	47	with	with	ADP
fnp-3528	1174	48	effects	effect	NOUN
fnp-3528	1174	49	on	on	ADP
fnp-3528	1174	50	liver	liver	NOUN
fnp-3528	1174	51	x	x	PUNCT
fnp-3528	1174	52	receptor	receptor	NOUN
fnp-3528	1174	53	alpha	alpha	NOUN
fnp-3528	1174	54	.	.	PUNCT
fnp-3528	1175	1	j	j	PROPN
fnp-3528	1175	2	nat	nat	PROPN
fnp-3528	1175	3	prod	prod	PROPN
fnp-3528	1175	4	2020	2020	NUM
fnp-3528	1175	5	,	,	PUNCT
fnp-3528	1175	6	83	83	NUM
fnp-3528	1175	7	,	,	PUNCT
fnp-3528	1175	8	1258	1258	NUM
fnp-3528	1175	9	-	-	SYM
fnp-3528	1175	10	64	64	NUM
fnp-3528	1175	11	.	.	PUNCT
fnp-3528	1176	1	chen	chen	PROPN
fnp-3528	1176	2	,	,	PUNCT
fnp-3528	1176	3	y.	y.	PROPN
fnp-3528	1176	4	;	;	PUNCT
fnp-3528	1176	5	wang	wang	PROPN
fnp-3528	1176	6	,	,	PUNCT
fnp-3528	1176	7	y.	y.	PROPN
fnp-3528	1176	8	;	;	PUNCT
fnp-3528	1176	9	yang	yang	PROPN
fnp-3528	1176	10	,	,	PUNCT
fnp-3528	1176	11	m.	m.	NOUN
fnp-3528	1176	12	;	;	PUNCT
fnp-3528	1176	13	guo	guo	PROPN
fnp-3528	1176	14	,	,	PUNCT
fnp-3528	1176	15	m.	m.	NOUN
fnp-3528	1176	16	y.	y.	PROPN
fnp-3528	1176	17	allicin	allicin	PROPN
fnp-3528	1176	18	inhibited	inhibit	VERB
fnp-3528	1176	19	staphylococcus	staphylococcus	NOUN
fnp-3528	1176	20	aureus	aureus	NOUN
fnp-3528	1176	21	-induced	-induce	VERB
fnp-3528	1176	22	mastitis	mastitis	NOUN
fnp-3528	1176	23	by	by	ADP
fnp-3528	1176	24	reducing	reduce	VERB
fnp-3528	1176	25	lipid	lipid	NOUN
fnp-3528	1176	26	raft	raft	NOUN
fnp-3528	1176	27	stability	stability	NOUN
fnp-3528	1176	28	via	via	ADP
fnp-3528	1176	29	lxralpha	lxralpha	PROPN
fnp-3528	1176	30	in	in	ADP
fnp-3528	1176	31	mice	mouse	NOUN
fnp-3528	1176	32	.	.	PUNCT
fnp-3528	1177	1	j	j	PROPN
fnp-3528	1177	2	agric	agric	PROPN
fnp-3528	1177	3	food	food	PROPN
fnp-3528	1177	4	chem	chem	NOUN
fnp-3528	1177	5	2019	2019	NUM
fnp-3528	1177	6	,	,	PUNCT
fnp-3528	1177	7	67	67	NUM
fnp-3528	1177	8	,	,	PUNCT
fnp-3528	1177	9	10863	10863	NUM
fnp-3528	1177	10	-	-	SYM
fnp-3528	1177	11	70	70	NUM
fnp-3528	1177	12	.	.	PUNCT
fnp-3528	1178	1	grinman	grinman	PROPN
fnp-3528	1178	2	,	,	PUNCT
fnp-3528	1178	3	d.	d.	PROPN
fnp-3528	1178	4	y.	y.	PROPN
fnp-3528	1178	5	;	;	PUNCT
fnp-3528	1178	6	careaga	careaga	PROPN
fnp-3528	1178	7	,	,	PUNCT
fnp-3528	1178	8	v.	v.	PROPN
fnp-3528	1178	9	p.	p.	NOUN
fnp-3528	1178	10	;	;	PUNCT
fnp-3528	1178	11	wellberg	wellberg	PROPN
fnp-3528	1178	12	,	,	PUNCT
fnp-3528	1178	13	e.	e.	PROPN
fnp-3528	1178	14	a.	a.	PROPN
fnp-3528	1178	15	;	;	PUNCT
fnp-3528	1178	16	dansey	dansey	NOUN
fnp-3528	1178	17	,	,	PUNCT
fnp-3528	1178	18	m.	m.	NOUN
fnp-3528	1178	19	v.	v.	PROPN
fnp-3528	1178	20	;	;	PUNCT
fnp-3528	1178	21	kordon	kordon	PROPN
fnp-3528	1178	22	,	,	PUNCT
fnp-3528	1178	23	e.	e.	PROPN
fnp-3528	1178	24	c.	c.	PROPN
fnp-3528	1178	25	;	;	PUNCT
fnp-3528	1178	26	anderson	anderson	PROPN
fnp-3528	1178	27	,	,	PUNCT
fnp-3528	1178	28	s.	s.	PROPN
fnp-3528	1178	29	m.	m.	PROPN
fnp-3528	1178	30	;	;	PUNCT
fnp-3528	1178	31	maier	maier	PROPN
fnp-3528	1178	32	,	,	PUNCT
fnp-3528	1178	33	m.	m.	PROPN
fnp-3528	1178	34	s.	s.	PROPN
fnp-3528	1178	35	;	;	PUNCT
fnp-3528	1178	36	burton	burton	PROPN
fnp-3528	1178	37	,	,	PUNCT
fnp-3528	1178	38	g.	g.	PROPN
fnp-3528	1178	39	;	;	PUNCT
fnp-3528	1178	40	maclean	maclean	PROPN
fnp-3528	1178	41	,	,	PUNCT
fnp-3528	1178	42	p.	p.	PROPN
fnp-3528	1178	43	s.	s.	PROPN
fnp-3528	1178	44	;	;	PUNCT
fnp-3528	1179	1	rudolph	rudolph	PROPN
fnp-3528	1179	2	,	,	PUNCT
fnp-3528	1179	3	m.	m.	PROPN
fnp-3528	1179	4	c.	c.	PROPN
fnp-3528	1179	5	;	;	PUNCT
fnp-3528	1179	6	pecci	pecci	PROPN
fnp-3528	1179	7	,	,	PUNCT
fnp-3528	1179	8	a.	a.	NOUN
fnp-3528	1179	9	liver	liver	NOUN
fnp-3528	1179	10	x	x	ADP
fnp-3528	1179	11	receptor	receptor	NOUN
fnp-3528	1179	12	-	-	PUNCT
fnp-3528	1179	13	alpha	alpha	NOUN
fnp-3528	1179	14	activation	activation	NOUN
fnp-3528	1179	15	enhances	enhance	VERB
fnp-3528	1179	16	cholesterol	cholesterol	NOUN
fnp-3528	1179	17	secretion	secretion	NOUN
fnp-3528	1179	18	in	in	ADP
fnp-3528	1179	19	lactating	lactate	VERB
fnp-3528	1179	20	mammary	mammary	ADJ
fnp-3528	1179	21	epithelium	epithelium	NOUN
fnp-3528	1179	22	.	.	PUNCT
fnp-3528	1180	1	american	american	ADJ
fnp-3528	1180	2	journal	journal	PROPN
fnp-3528	1180	3	of	of	ADP
fnp-3528	1180	4	physiology	physiology	NOUN
fnp-3528	1180	5	.	.	PUNCT
fnp-3528	1181	1	endocrinol	endocrinol	VERB
fnp-3528	1181	2	metab	metab	NOUN
fnp-3528	1181	3	2019	2019	NUM
fnp-3528	1181	4	,	,	PUNCT
fnp-3528	1181	5	316	316	NUM
fnp-3528	1181	6	,	,	PUNCT
fnp-3528	1181	7	e1136	e1136	NOUN
fnp-3528	1181	8	-	-	PUNCT
fnp-3528	1181	9	e1145	e1145	NOUN
fnp-3528	1181	10	.	.	PUNCT
fnp-3528	1182	1	huang	huang	PROPN
fnp-3528	1182	2	,	,	PUNCT
fnp-3528	1182	3	y.	y.	PROPN
fnp-3528	1182	4	;	;	PUNCT
fnp-3528	1182	5	liu	liu	PROPN
fnp-3528	1182	6	,	,	PUNCT
fnp-3528	1182	7	h.	h.	PROPN
fnp-3528	1182	8	;	;	PUNCT
fnp-3528	1182	9	zhang	zhang	PROPN
fnp-3528	1182	10	,	,	PUNCT
fnp-3528	1182	11	y.	y.	PROPN
fnp-3528	1182	12	;	;	PUNCT
fnp-3528	1182	13	li	li	PROPN
fnp-3528	1182	14	,	,	PUNCT
fnp-3528	1182	15	j.	j.	PROPN
fnp-3528	1182	16	;	;	PUNCT
fnp-3528	1182	17	wang	wang	PROPN
fnp-3528	1182	18	,	,	PUNCT
fnp-3528	1182	19	c.	c.	PROPN
fnp-3528	1182	20	;	;	PUNCT
fnp-3528	1182	21	zhou	zhou	PROPN
fnp-3528	1182	22	,	,	PUNCT
fnp-3528	1182	23	l.	l.	PROPN
fnp-3528	1182	24	;	;	PUNCT
fnp-3528	1182	25	jia	jia	PROPN
fnp-3528	1182	26	,	,	PUNCT
fnp-3528	1182	27	y.	y.	PROPN
fnp-3528	1182	28	;	;	PUNCT
fnp-3528	1182	29	li	li	PROPN
fnp-3528	1182	30	,	,	PUNCT
fnp-3528	1182	31	x.	x.	NOUN
fnp-3528	1182	32	synthesis	synthesis	NOUN
fnp-3528	1182	33	and	and	CCONJ
fnp-3528	1182	34	biological	biological	ADJ
fnp-3528	1182	35	evaluation	evaluation	NOUN
fnp-3528	1182	36	of	of	ADP
fnp-3528	1182	37	ginsenoside	ginsenoside	ADJ
fnp-3528	1182	38	compound	compound	NOUN
fnp-3528	1182	39	k	k	NOUN
fnp-3528	1182	40	derivatives	derivative	NOUN
fnp-3528	1182	41	as	as	ADP
fnp-3528	1182	42	a	a	DET
fnp-3528	1182	43	novel	novel	ADJ
fnp-3528	1182	44	class	class	NOUN
fnp-3528	1182	45	of	of	ADP
fnp-3528	1182	46	lxralpha	lxralpha	PROPN
fnp-3528	1182	47	activator	activator	NOUN
fnp-3528	1182	48	.	.	PUNCT
fnp-3528	1183	1	molecules	molecule	NOUN
fnp-3528	1183	2	2017	2017	NUM
fnp-3528	1183	3	,	,	PUNCT
fnp-3528	1183	4	22	22	NUM
fnp-3528	1183	5	,	,	PUNCT
fnp-3528	1183	6	1232	1232	NUM
fnp-3528	1183	7	.	.	PUNCT
fnp-3528	1184	1	liu	liu	PROPN
fnp-3528	1184	2	,	,	PUNCT
fnp-3528	1184	3	b.	b.	PROPN
fnp-3528	1184	4	;	;	PUNCT
fnp-3528	1184	5	he	he	PRON
fnp-3528	1184	6	,	,	PUNCT
fnp-3528	1184	7	z.	z.	PROPN
fnp-3528	1184	8	;	;	PUNCT
fnp-3528	1184	9	wang	wang	PROPN
fnp-3528	1184	10	,	,	PUNCT
fnp-3528	1184	11	j.	j.	PROPN
fnp-3528	1184	12	;	;	PUNCT
fnp-3528	1184	13	xin	xin	PROPN
fnp-3528	1184	14	,	,	PUNCT
fnp-3528	1184	15	z.	z.	PROPN
fnp-3528	1184	16	;	;	PUNCT
fnp-3528	1184	17	wang	wang	PROPN
fnp-3528	1184	18	,	,	PUNCT
fnp-3528	1184	19	j.	j.	PROPN
fnp-3528	1184	20	;	;	PUNCT
fnp-3528	1184	21	li	li	PROPN
fnp-3528	1184	22	,	,	PUNCT
fnp-3528	1184	23	f.	f.	PROPN
fnp-3528	1184	24	;	;	PUNCT
fnp-3528	1184	25	fu	fu	PROPN
fnp-3528	1184	26	,	,	PUNCT
fnp-3528	1184	27	y.	y.	PROPN
fnp-3528	1184	28	taraxasterol	taraxasterol	PROPN
fnp-3528	1184	29	inhibits	inhibit	VERB
fnp-3528	1184	30	lps	lps	PROPN
fnp-3528	1184	31	-	-	PUNCT
fnp-3528	1184	32	induced	induce	VERB
fnp-3528	1184	33	inflammatory	inflammatory	ADJ
fnp-3528	1184	34	response	response	NOUN
fnp-3528	1184	35	in	in	ADP
fnp-3528	1184	36	bv2	bv2	NOUN
fnp-3528	1184	37	microglia	microglia	ADJ
fnp-3528	1184	38	cells	cell	NOUN
fnp-3528	1184	39	by	by	ADP
fnp-3528	1184	40	activating	activate	VERB
fnp-3528	1184	41	lxralpha	lxralpha	NOUN
fnp-3528	1184	42	.	.	PUNCT
fnp-3528	1185	1	front	front	ADJ
fnp-3528	1185	2	pharmacol	pharmacol	PROPN
fnp-3528	1185	3	2018	2018	NUM
fnp-3528	1185	4	,	,	PUNCT
fnp-3528	1185	5	9	9	NUM
fnp-3528	1185	6	,	,	PUNCT
fnp-3528	1185	7	278	278	NUM
fnp-3528	1185	8	.	.	PUNCT
fnp-3528	1186	1	biswas	biswas	PROPN
fnp-3528	1186	2	,	,	PUNCT
fnp-3528	1186	3	l.	l.	PROPN
fnp-3528	1186	4	;	;	PUNCT
fnp-3528	1186	5	zeng	zeng	PROPN
fnp-3528	1186	6	,	,	PUNCT
fnp-3528	1186	7	z.	z.	PROPN
fnp-3528	1186	8	;	;	PUNCT
fnp-3528	1186	9	graham	graham	PROPN
fnp-3528	1186	10	,	,	PUNCT
fnp-3528	1186	11	a.	a.	PROPN
fnp-3528	1186	12	;	;	PUNCT
fnp-3528	1186	13	shu	shu	PROPN
fnp-3528	1186	14	,	,	PUNCT
fnp-3528	1186	15	x.	x.	PROPN
fnp-3528	1186	16	gypenosides	gypenoside	NOUN
fnp-3528	1186	17	mediate	mediate	VERB
fnp-3528	1186	18	cholesterol	cholesterol	NOUN
fnp-3528	1186	19	efflux	efflux	NOUN
fnp-3528	1186	20	and	and	CCONJ
fnp-3528	1186	21	suppress	suppress	VERB
fnp-3528	1186	22	oxidized	oxidize	VERB
fnp-3528	1186	23	ldl	ldl	NOUN
fnp-3528	1186	24	induced	induce	VERB
fnp-3528	1186	25	inflammation	inflammation	NOUN
fnp-3528	1186	26	in	in	ADP
fnp-3528	1186	27	retinal	retinal	ADJ
fnp-3528	1186	28	pigment	pigment	NOUN
fnp-3528	1186	29	epithelium	epithelium	NOUN
fnp-3528	1186	30	cells	cell	NOUN
fnp-3528	1186	31	.	.	PUNCT
fnp-3528	1187	1	exp	exp	NOUN
fnp-3528	1187	2	eye	eye	NOUN
fnp-3528	1187	3	res	re	NOUN
fnp-3528	1187	4	2020	2020	NUM
fnp-3528	1187	5	,	,	PUNCT
fnp-3528	1187	6	191	191	NUM
fnp-3528	1187	7	,	,	PUNCT
fnp-3528	1187	8	107931	107931	NUM
fnp-3528	1187	9	.	.	PUNCT
fnp-3528	1188	1	fu	fu	PROPN
fnp-3528	1188	2	,	,	PUNCT
fnp-3528	1188	3	y.	y.	PROPN
fnp-3528	1188	4	;	;	PUNCT
fnp-3528	1188	5	xin	xin	PROPN
fnp-3528	1188	6	,	,	PUNCT
fnp-3528	1188	7	z.	z.	PROPN
fnp-3528	1188	8	;	;	PUNCT
fnp-3528	1188	9	liu	liu	PROPN
fnp-3528	1188	10	,	,	PUNCT
fnp-3528	1188	11	b.	b.	PROPN
fnp-3528	1188	12	;	;	PUNCT
fnp-3528	1188	13	wang	wang	PROPN
fnp-3528	1188	14	,	,	PUNCT
fnp-3528	1188	15	j.	j.	PROPN
fnp-3528	1188	16	;	;	PUNCT
fnp-3528	1188	17	wang	wang	PROPN
fnp-3528	1188	18	,	,	PUNCT
fnp-3528	1188	19	j.	j.	PROPN
fnp-3528	1188	20	;	;	PUNCT
fnp-3528	1188	21	zhang	zhang	PROPN
fnp-3528	1188	22	,	,	PUNCT
fnp-3528	1188	23	x.	x.	PROPN
fnp-3528	1188	24	;	;	PUNCT
fnp-3528	1188	25	wang	wang	PROPN
fnp-3528	1188	26	,	,	PUNCT
fnp-3528	1188	27	y.	y.	PROPN
fnp-3528	1188	28	;	;	PUNCT
fnp-3528	1188	29	li	li	PROPN
fnp-3528	1188	30	,	,	PUNCT
fnp-3528	1188	31	f.	f.	PROPN
fnp-3528	1188	32	platycodin	platycodin	PROPN
fnp-3528	1188	33	d	d	PROPN
fnp-3528	1188	34	inhibits	inhibit	VERB
fnp-3528	1188	35	inflammatory	inflammatory	ADJ
fnp-3528	1188	36	response	response	NOUN
fnp-3528	1188	37	in	in	ADP
fnp-3528	1188	38	lps	lps	PROPN
fnp-3528	1188	39	-	-	PUNCT
fnp-3528	1188	40	stimulated	stimulate	VERB
fnp-3528	1188	41	primary	primary	ADJ
fnp-3528	1188	42	rat	rat	NOUN
fnp-3528	1188	43	microglia	microglia	ADJ
fnp-3528	1188	44	cells	cell	NOUN
fnp-3528	1188	45	through	through	ADP
fnp-3528	1188	46	activating	activate	VERB
fnp-3528	1188	47	lxralpha	lxralpha	NOUN
fnp-3528	1188	48	-	-	PUNCT
fnp-3528	1188	49	abca1	abca1	NOUN
fnp-3528	1188	50	signaling	signal	VERB
fnp-3528	1188	51	pathway	pathway	NOUN
fnp-3528	1188	52	.	.	PUNCT
fnp-3528	1189	1	front	front	ADJ
fnp-3528	1189	2	immunol	immunol	NOUN
fnp-3528	1189	3	2017	2017	NUM
fnp-3528	1189	4	,	,	PUNCT
fnp-3528	1189	5	8	8	NUM
fnp-3528	1189	6	,	,	PUNCT
fnp-3528	1189	7	1929	1929	NUM
fnp-3528	1189	8	.	.	PUNCT
fnp-3528	1190	1	shuai	shuai	PROPN
fnp-3528	1190	2	-	-	PUNCT
fnp-3528	1190	3	cheng	cheng	PROPN
fnp-3528	1190	4	,	,	PUNCT
fnp-3528	1190	5	w.	w.	PROPN
fnp-3528	1190	6	;	;	PUNCT
fnp-3528	1190	7	xiu	xiu	PROPN
fnp-3528	1190	8	-	-	PUNCT
fnp-3528	1190	9	ling	ling	PROPN
fnp-3528	1190	10	,	,	PUNCT
fnp-3528	1190	11	c.	c.	PROPN
fnp-3528	1190	12	;	;	PUNCT
fnp-3528	1190	13	jian	jian	PROPN
fnp-3528	1190	14	-	-	PUNCT
fnp-3528	1190	15	qing	qing	PROPN
fnp-3528	1190	16	,	,	PUNCT
fnp-3528	1190	17	s.	s.	PROPN
fnp-3528	1190	18	;	;	PUNCT
fnp-3528	1190	19	zong	zong	PROPN
fnp-3528	1190	20	-	-	PUNCT
fnp-3528	1190	21	mei	mei	PROPN
fnp-3528	1190	22	,	,	PUNCT
fnp-3528	1190	23	w.	w.	PROPN
fnp-3528	1190	24	;	;	PUNCT
fnp-3528	1190	25	zhen	zhen	PROPN
fnp-3528	1190	26	-	-	PUNCT
fnp-3528	1190	27	jiang	jiang	PROPN
fnp-3528	1190	28	,	,	PUNCT
fnp-3528	1190	29	y.	y.	PROPN
fnp-3528	1190	30	;	;	PUNCT
fnp-3528	1190	31	lian	lian	PROPN
fnp-3528	1190	32	-	-	PUNCT
fnp-3528	1190	33	tao	tao	PROPN
fnp-3528	1190	34	,	,	PUNCT
fnp-3528	1190	35	l.	l.	PROPN
fnp-3528	1190	36	saikosaponin	saikosaponin	PROPN
fnp-3528	1190	37	a	a	DET
fnp-3528	1190	38	protects	protect	VERB
fnp-3528	1190	39	chickens	chicken	NOUN
fnp-3528	1190	40	against	against	ADP
fnp-3528	1190	41	pullorum	pullorum	ADJ
fnp-3528	1190	42	disease	disease	NOUN
fnp-3528	1190	43	via	via	ADP
fnp-3528	1190	44	modulation	modulation	NOUN
fnp-3528	1190	45	of	of	ADP
fnp-3528	1190	46	cholesterol	cholesterol	NOUN
fnp-3528	1190	47	.	.	PUNCT
fnp-3528	1191	1	poult	poult	NOUN
fnp-3528	1191	2	sci	sci	PROPN
fnp-3528	1191	3	2019	2019	NUM
fnp-3528	1191	4	,	,	PUNCT
fnp-3528	1191	5	98	98	NUM
fnp-3528	1191	6	,	,	PUNCT
fnp-3528	1191	7	3539	3539	NUM
fnp-3528	1191	8	-	-	SYM
fnp-3528	1191	9	47	47	NUM
fnp-3528	1191	10	.	.	PUNCT
fnp-3528	1192	1	kilby	kilby	PROPN
fnp-3528	1192	2	,	,	PUNCT
fnp-3528	1192	3	e.	e.	PROPN
fnp-3528	1192	4	l.	l.	PROPN
fnp-3528	1192	5	;	;	PUNCT
fnp-3528	1192	6	kelly	kelly	PROPN
fnp-3528	1192	7	,	,	PUNCT
fnp-3528	1192	8	d.	d.	PROPN
fnp-3528	1192	9	m.	m.	PROPN
fnp-3528	1192	10	;	;	PUNCT
fnp-3528	1192	11	jones	jones	PROPN
fnp-3528	1192	12	,	,	PUNCT
fnp-3528	1192	13	t.	t.	PROPN
fnp-3528	1192	14	h.	h.	PROPN
fnp-3528	1192	15	testosterone	testosterone	PROPN
fnp-3528	1192	16	stimulates	stimulate	VERB
fnp-3528	1192	17	cholesterol	cholesterol	NOUN
fnp-3528	1192	18	clearance	clearance	NOUN
fnp-3528	1192	19	from	from	ADP
fnp-3528	1192	20	human	human	ADJ
fnp-3528	1192	21	macrophages	macrophage	NOUN
fnp-3528	1192	22	by	by	ADP
fnp-3528	1192	23	activating	activate	VERB
fnp-3528	1192	24	lxralpha	lxralpha	NOUN
fnp-3528	1192	25	.	.	PUNCT
fnp-3528	1193	1	life	life	NOUN
fnp-3528	1193	2	sci	sci	PROPN
fnp-3528	1193	3	2021	2021	NUM
fnp-3528	1193	4	,	,	PUNCT
fnp-3528	1193	5	269	269	NUM
fnp-3528	1193	6	,	,	PUNCT
fnp-3528	1193	7	119040	119040	NUM
fnp-3528	1193	8	.	.	PUNCT
fnp-3528	1194	1	li	li	PROPN
fnp-3528	1194	2	,	,	PUNCT
fnp-3528	1194	3	s.	s.	PROPN
fnp-3528	1194	4	;	;	PUNCT
fnp-3528	1194	5	cao	cao	PROPN
fnp-3528	1194	6	,	,	PUNCT
fnp-3528	1194	7	h.	h.	PROPN
fnp-3528	1194	8	;	;	PUNCT
fnp-3528	1194	9	shen	shen	PROPN
fnp-3528	1194	10	,	,	PUNCT
fnp-3528	1194	11	d.	d.	PROPN
fnp-3528	1194	12	;	;	PUNCT
fnp-3528	1194	13	jia	jia	PROPN
fnp-3528	1194	14	,	,	PUNCT
fnp-3528	1194	15	q.	q.	PROPN
fnp-3528	1194	16	;	;	PUNCT
fnp-3528	1194	17	chen	chen	PROPN
fnp-3528	1194	18	,	,	PUNCT
fnp-3528	1194	19	c.	c.	PROPN
fnp-3528	1194	20	;	;	PUNCT
fnp-3528	1194	21	xing	xing	PROPN
fnp-3528	1194	22	,	,	PUNCT
fnp-3528	1194	23	s.	s.	PROPN
fnp-3528	1194	24	l.	l.	PROPN
fnp-3528	1194	25	quercetin	quercetin	PROPN
fnp-3528	1194	26	protects	protect	VERB
fnp-3528	1194	27	against	against	ADP
fnp-3528	1194	28	oxldlinduced	oxldlinduced	ADJ
fnp-3528	1194	29	injury	injury	NOUN
fnp-3528	1194	30	via	via	ADP
fnp-3528	1194	31	regulation	regulation	NOUN
fnp-3528	1194	32	of	of	ADP
fnp-3528	1194	33	abcal	abcal	ADJ
fnp-3528	1194	34	,	,	PUNCT
fnp-3528	1194	35	lxralpha	lxralpha	NOUN
fnp-3528	1194	36	and	and	CCONJ
fnp-3528	1194	37	pcsk9	pcsk9	NOUN
fnp-3528	1194	38	in	in	ADP
fnp-3528	1194	39	raw264.7	raw264.7	PROPN
fnp-3528	1194	40	macrophages	macrophage	NOUN
fnp-3528	1194	41	.	.	PUNCT
fnp-3528	1195	1	mol	mol	ADP
fnp-3528	1195	2	med	med	PROPN
fnp-3528	1195	3	rep	rep	PROPN
fnp-3528	1195	4	2018	2018	NUM
fnp-3528	1195	5	,	,	PUNCT
fnp-3528	1195	6	18	18	NUM
fnp-3528	1195	7	,	,	PUNCT
fnp-3528	1195	8	799	799	NUM
fnp-3528	1195	9	-	-	SYM
fnp-3528	1195	10	806	806	NUM
fnp-3528	1195	11	.	.	PUNCT
fnp-3528	1196	1	malar	malar	PROPN
fnp-3528	1196	2	,	,	PUNCT
fnp-3528	1196	3	d.	d.	PROPN
fnp-3528	1196	4	s.	s.	PROPN
fnp-3528	1196	5	;	;	PUNCT
fnp-3528	1196	6	suryanarayanan	suryanarayanan	PROPN
fnp-3528	1196	7	,	,	PUNCT
fnp-3528	1196	8	v.	v.	ADV
fnp-3528	1196	9	;	;	PUNCT
fnp-3528	1196	10	prasanth	prasanth	NOUN
fnp-3528	1196	11	,	,	PUNCT
fnp-3528	1196	12	m.	m.	NOUN
fnp-3528	1196	13	i.	i.	PROPN
fnp-3528	1196	14	;	;	PUNCT
fnp-3528	1196	15	singh	singh	PROPN
fnp-3528	1196	16	,	,	PUNCT
fnp-3528	1196	17	s.	s.	PROPN
fnp-3528	1196	18	k.	k.	PROPN
fnp-3528	1196	19	;	;	PUNCT
fnp-3528	1196	20	balamurugan	balamurugan	VERB
fnp-3528	1196	21	,	,	PUNCT
fnp-3528	1196	22	k.	k.	PROPN
fnp-3528	1196	23	;	;	PUNCT
fnp-3528	1196	24	devi	devi	PROPN
fnp-3528	1196	25	,	,	PUNCT
fnp-3528	1196	26	k.	k.	PROPN
fnp-3528	1197	1	p.	p.	PROPN
fnp-3528	1197	2	vitexin	vitexin	PROPN
fnp-3528	1197	3	inhibits	inhibit	VERB
fnp-3528	1197	4	abeta25	abeta25	PROPN
fnp-3528	1197	5	-	-	PUNCT
fnp-3528	1197	6	35	35	NUM
fnp-3528	1197	7	induced	induced	ADJ
fnp-3528	1197	8	toxicity	toxicity	NOUN
fnp-3528	1197	9	in	in	ADP
fnp-3528	1197	10	neuro-2a	neuro-2a	NOUN
fnp-3528	1197	11	cells	cell	NOUN
fnp-3528	1197	12	by	by	ADP
fnp-3528	1197	13	augmenting	augment	VERB
fnp-3528	1197	14	nrf-2	nrf-2	NOUN
fnp-3528	1197	15	/	/	SYM
fnp-3528	1197	16	ho-1	ho-1	ADJ
fnp-3528	1197	17	dependent	dependent	ADJ
fnp-3528	1197	18	antioxidant	antioxidant	ADJ
fnp-3528	1197	19	pathway	pathway	NOUN
fnp-3528	1197	20	and	and	CCONJ
fnp-3528	1197	21	regulating	regulate	VERB
fnp-3528	1197	22	lipid	lipid	NOUN
fnp-3528	1197	23	homeostasis	homeostasis	NOUN
fnp-3528	1197	24	by	by	ADP
fnp-3528	1197	25	the	the	DET
fnp-3528	1197	26	activation	activation	NOUN
fnp-3528	1197	27	of	of	ADP
fnp-3528	1197	28	lxr	lxr	NOUN
fnp-3528	1197	29	-	-	PUNCT
fnp-3528	1197	30	alpha	alpha	NOUN
fnp-3528	1197	31	.	.	PUNCT
fnp-3528	1198	1	toxicol	toxicol	PROPN
fnp-3528	1198	2	in	in	ADP
fnp-3528	1198	3	vitro	vitro	X
fnp-3528	1198	4	2018	2018	NUM
fnp-3528	1198	5	,	,	PUNCT
fnp-3528	1198	6	50	50	NUM
fnp-3528	1198	7	,	,	PUNCT
fnp-3528	1198	8	160	160	NUM
fnp-3528	1198	9	-	-	SYM
fnp-3528	1198	10	171	171	NUM
fnp-3528	1198	11	.	.	PUNCT
fnp-3528	1199	1	xu	xu	INTJ
fnp-3528	1199	2	,	,	PUNCT
fnp-3528	1199	3	x.	x.	PROPN
fnp-3528	1199	4	;	;	PUNCT
fnp-3528	1199	5	lei	lei	PROPN
fnp-3528	1199	6	,	,	PUNCT
fnp-3528	1199	7	t.	t.	PROPN
fnp-3528	1199	8	;	;	PUNCT
fnp-3528	1199	9	li	li	PROPN
fnp-3528	1199	10	,	,	PUNCT
fnp-3528	1199	11	w.	w.	PROPN
fnp-3528	1199	12	;	;	PUNCT
fnp-3528	1199	13	ou	ou	PROPN
fnp-3528	1199	14	,	,	PUNCT
fnp-3528	1199	15	h.	h.	PROPN
fnp-3528	1199	16	enhanced	enhance	VERB
fnp-3528	1199	17	cellular	cellular	ADJ
fnp-3528	1199	18	cholesterol	cholesterol	NOUN
fnp-3528	1199	19	efflux	efflux	NOUN
fnp-3528	1199	20	by	by	ADP
fnp-3528	1199	21	naringenin	naringenin	PROPN
fnp-3528	1199	22	is	be	AUX
fnp-3528	1199	23	mediated	mediate	VERB
fnp-3528	1199	24	through	through	ADP
fnp-3528	1199	25	inhibiting	inhibit	VERB
fnp-3528	1199	26	endoplasmic	endoplasmic	ADJ
fnp-3528	1199	27	reticulum	reticulum	NOUN
fnp-3528	1199	28	stress	stress	VERB
fnp-3528	1199	29	atf6	atf6	NOUN
fnp-3528	1199	30	activity	activity	NOUN
fnp-3528	1199	31	in	in	ADP
fnp-3528	1199	32	macrophages	macrophage	NOUN
fnp-3528	1199	33	.	.	PUNCT
fnp-3528	1200	1	biochim	biochim	PROPN
fnp-3528	1200	2	biophys	biophy	NOUN
fnp-3528	1200	3	acta	acta	PROPN
fnp-3528	1200	4	mol	mol	ADP
fnp-3528	1200	5	cell	cell	NOUN
fnp-3528	1200	6	biol	biol	NOUN
fnp-3528	1200	7	lipids	lipid	VERB
fnp-3528	1200	8	2019	2019	NUM
fnp-3528	1200	9	,	,	PUNCT
fnp-3528	1200	10	1864	1864	NUM
fnp-3528	1200	11	,	,	PUNCT
fnp-3528	1200	12	1472	1472	NUM
fnp-3528	1200	13	-	-	SYM
fnp-3528	1200	14	82	82	NUM
fnp-3528	1200	15	.	.	PUNCT
fnp-3528	1201	1	jia	jia	PROPN
fnp-3528	1201	2	,	,	PUNCT
fnp-3528	1201	3	q.	q.	PROPN
fnp-3528	1201	4	;	;	PUNCT
fnp-3528	1201	5	cao	cao	PROPN
fnp-3528	1201	6	,	,	PUNCT
fnp-3528	1201	7	h.	h.	PROPN
fnp-3528	1201	8	;	;	PUNCT
fnp-3528	1201	9	shen	shen	PROPN
fnp-3528	1201	10	,	,	PUNCT
fnp-3528	1201	11	d.	d.	PROPN
fnp-3528	1201	12	;	;	PUNCT
fnp-3528	1201	13	li	li	PROPN
fnp-3528	1201	14	,	,	PUNCT
fnp-3528	1201	15	s.	s.	PROPN
fnp-3528	1201	16	;	;	PUNCT
fnp-3528	1201	17	yan	yan	PROPN
fnp-3528	1201	18	,	,	PUNCT
fnp-3528	1201	19	l.	l.	PROPN
fnp-3528	1201	20	;	;	PUNCT
fnp-3528	1201	21	chen	chen	PROPN
fnp-3528	1201	22	,	,	PUNCT
fnp-3528	1201	23	c.	c.	PROPN
fnp-3528	1201	24	;	;	PUNCT
fnp-3528	1201	25	xing	xing	PROPN
fnp-3528	1201	26	,	,	PUNCT
fnp-3528	1201	27	s.	s.	PROPN
fnp-3528	1201	28	;	;	PUNCT
fnp-3528	1201	29	dou	dou	PROPN
fnp-3528	1201	30	,	,	PUNCT
fnp-3528	1201	31	f.	f.	PROPN
fnp-3528	1201	32	quercetin	quercetin	NOUN
fnp-3528	1201	33	protects	protect	VERB
fnp-3528	1201	34	against	against	ADP
fnp-3528	1201	35	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1201	36	by	by	ADP
fnp-3528	1201	37	regulating	regulate	VERB
fnp-3528	1201	38	the	the	DET
fnp-3528	1201	39	expression	expression	NOUN
fnp-3528	1201	40	of	of	ADP
fnp-3528	1201	41	pcsk9	pcsk9	PROPN
fnp-3528	1201	42	,	,	PUNCT
fnp-3528	1201	43	cd36	cd36	PROPN
fnp-3528	1201	44	,	,	PUNCT
fnp-3528	1201	45	ppargamma	ppargamma	NOUN
fnp-3528	1201	46	,	,	PUNCT
fnp-3528	1201	47	lxralpha	lxralpha	NOUN
fnp-3528	1201	48	and	and	CCONJ
fnp-3528	1201	49	abca1	abca1	PROPN
fnp-3528	1201	50	.	.	PUNCT
fnp-3528	1202	1	int	int	PROPN
fnp-3528	1202	2	j	j	PROPN
fnp-3528	1202	3	mol	mol	ADP
fnp-3528	1202	4	med	med	PROPN
fnp-3528	1202	5	2019	2019	NUM
fnp-3528	1202	6	,	,	PUNCT
fnp-3528	1202	7	44	44	NUM
fnp-3528	1202	8	,	,	PUNCT
fnp-3528	1202	9	893	893	NUM
fnp-3528	1202	10	-	-	SYM
fnp-3528	1202	11	902	902	NUM
fnp-3528	1202	12	.	.	PUNCT
fnp-3528	1203	1	li	li	PROPN
fnp-3528	1203	2	,	,	PUNCT
fnp-3528	1203	3	s.	s.	PROPN
fnp-3528	1203	4	s.	s.	PROPN
fnp-3528	1203	5	;	;	PUNCT
fnp-3528	1203	6	cao	cao	PROPN
fnp-3528	1203	7	,	,	PUNCT
fnp-3528	1203	8	h.	h.	PROPN
fnp-3528	1203	9	;	;	PUNCT
fnp-3528	1203	10	shen	shen	PROPN
fnp-3528	1203	11	,	,	PUNCT
fnp-3528	1203	12	d.	d.	PROPN
fnp-3528	1203	13	z.	z.	PROPN
fnp-3528	1203	14	;	;	PUNCT
fnp-3528	1203	15	chen	chen	PROPN
fnp-3528	1203	16	,	,	PUNCT
fnp-3528	1203	17	c.	c.	PROPN
fnp-3528	1203	18	;	;	PUNCT
fnp-3528	1203	19	xing	xing	PROPN
fnp-3528	1203	20	,	,	PUNCT
fnp-3528	1203	21	s.	s.	PROPN
fnp-3528	1203	22	l.	l.	PROPN
fnp-3528	1203	23	;	;	PUNCT
fnp-3528	1203	24	dou	dou	PROPN
fnp-3528	1203	25	,	,	PUNCT
fnp-3528	1203	26	f.	f.	PROPN
fnp-3528	1203	27	f.	f.	PROPN
fnp-3528	1203	28	;	;	PUNCT
fnp-3528	1203	29	jia	jia	PROPN
fnp-3528	1203	30	,	,	PUNCT
fnp-3528	1203	31	q.	q.	PROPN
fnp-3528	1203	32	l.	l.	PROPN
fnp-3528	1203	33	effect	effect	PROPN
fnp-3528	1203	34	of	of	ADP
fnp-3528	1203	35	quercetin	quercetin	NOUN
fnp-3528	1203	36	on	on	ADP
fnp-3528	1203	37	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1203	38	based	base	VERB
fnp-3528	1203	39	on	on	ADP
fnp-3528	1203	40	expressions	expression	NOUN
fnp-3528	1203	41	of	of	ADP
fnp-3528	1203	42	abca1	abca1	NOUN
fnp-3528	1203	43	,	,	PUNCT
fnp-3528	1203	44	lxr	lxr	NOUN
fnp-3528	1203	45	-	-	PUNCT
fnp-3528	1203	46	alpha	alpha	NOUN
fnp-3528	1203	47	and	and	CCONJ
fnp-3528	1203	48	pcsk	pcsk	NOUN
fnp-3528	1203	49	in	in	ADP
fnp-3528	1203	50	apoe(-/-	apoe(-/-	NUM
fnp-3528	1203	51	)	)	PUNCT
fnp-3528	1203	52	mice	mouse	NOUN
fnp-3528	1203	53	.	.	PUNCT
fnp-3528	1204	1	chin	chin	PROPN
fnp-3528	1204	2	j	j	PROPN
fnp-3528	1204	3	integr	integr	PROPN
fnp-3528	1204	4	med	me	VERB
fnp-3528	1204	5	2020	2020	NUM
fnp-3528	1204	6	,	,	PUNCT
fnp-3528	1204	7	26	26	NUM
fnp-3528	1204	8	,	,	PUNCT
fnp-3528	1204	9	114	114	NUM
fnp-3528	1204	10	-	-	SYM
fnp-3528	1204	11	21	21	NUM
fnp-3528	1204	12	.	.	PUNCT
fnp-3528	1205	1	teng	teng	PROPN
fnp-3528	1205	2	,	,	PUNCT
fnp-3528	1205	3	i.	i.	PROPN
fnp-3528	1205	4	j.	j.	PROPN
fnp-3528	1205	5	;	;	PUNCT
fnp-3528	1205	6	tsai	tsai	PROPN
fnp-3528	1205	7	,	,	PUNCT
fnp-3528	1205	8	m.	m.	PROPN
fnp-3528	1205	9	c.	c.	PROPN
fnp-3528	1205	10	;	;	PUNCT
fnp-3528	1205	11	shih	shih	PROPN
fnp-3528	1205	12	,	,	PUNCT
fnp-3528	1205	13	s.	s.	PROPN
fnp-3528	1205	14	f.	f.	PROPN
fnp-3528	1205	15	;	;	PUNCT
fnp-3528	1205	16	tsuei	tsuei	PROPN
fnp-3528	1205	17	,	,	PUNCT
fnp-3528	1205	18	b.	b.	PROPN
fnp-3528	1205	19	f.	f.	PROPN
fnp-3528	1205	20	;	;	PUNCT
fnp-3528	1205	21	chang	chang	PROPN
fnp-3528	1205	22	,	,	PUNCT
fnp-3528	1205	23	h.	h.	PROPN
fnp-3528	1205	24	;	;	PUNCT
fnp-3528	1205	25	chuang	chuang	PROPN
fnp-3528	1205	26	,	,	PUNCT
fnp-3528	1205	27	y.	y.	PROPN
fnp-3528	1205	28	p.	p.	PROPN
fnp-3528	1205	29	;	;	PUNCT
fnp-3528	1205	30	lin	lin	PROPN
fnp-3528	1205	31	,	,	PUNCT
fnp-3528	1205	32	c.	c.	PROPN
fnp-3528	1205	33	s.	s.	PROPN
fnp-3528	1205	34	;	;	PUNCT
fnp-3528	1205	35	chern	chern	PROPN
fnp-3528	1205	36	,	,	PUNCT
fnp-3528	1205	37	c.	c.	PROPN
fnp-3528	1205	38	y.	y.	PROPN
fnp-3528	1205	39	;	;	PUNCT
fnp-3528	1205	40	chen	chen	PROPN
fnp-3528	1205	41	,	,	PUNCT
fnp-3528	1205	42	s.	s.	PROPN
fnp-3528	1205	43	j.	j.	PROPN
fnp-3528	1205	44	chalcone	chalcone	PROPN
fnp-3528	1205	45	derivatives	derivative	NOUN
fnp-3528	1205	46	enhance	enhance	VERB
fnp-3528	1205	47	atp	atp	NOUN
fnp-3528	1205	48	-	-	PUNCT
fnp-3528	1205	49	binding	bind	VERB
fnp-3528	1205	50	cassette	cassette	NOUN
fnp-3528	1205	51	transporters	transporter	NOUN
fnp-3528	1205	52	a1	a1	NOUN
fnp-3528	1205	53	in	in	ADP
fnp-3528	1205	54	human	human	ADJ
fnp-3528	1205	55	thp-1	thp-1	X
fnp-3528	1205	56	macrophages	macrophage	NOUN
fnp-3528	1205	57	.	.	PUNCT
fnp-3528	1206	1	molecules	molecule	NOUN
fnp-3528	1206	2	2018	2018	NUM
fnp-3528	1206	3	,	,	PUNCT
fnp-3528	1206	4	23	23	NUM
fnp-3528	1206	5	,	,	PUNCT
fnp-3528	1206	6	1620	1620	NUM
fnp-3528	1206	7	.	.	PUNCT
fnp-3528	1207	1	chen	chen	PROPN
fnp-3528	1207	2	,	,	PUNCT
fnp-3528	1207	3	l.	l.	PROPN
fnp-3528	1207	4	w.	w.	PROPN
fnp-3528	1207	5	;	;	PUNCT
fnp-3528	1207	6	tsai	tsai	PROPN
fnp-3528	1207	7	,	,	PUNCT
fnp-3528	1207	8	m.	m.	PROPN
fnp-3528	1207	9	c.	c.	PROPN
fnp-3528	1207	10	;	;	PUNCT
fnp-3528	1207	11	chern	chern	PROPN
fnp-3528	1207	12	,	,	PUNCT
fnp-3528	1207	13	c.	c.	PROPN
fnp-3528	1207	14	y.	y.	PROPN
fnp-3528	1207	15	;	;	PUNCT
fnp-3528	1207	16	tsao	tsao	PROPN
fnp-3528	1207	17	,	,	PUNCT
fnp-3528	1207	18	t.	t.	PROPN
fnp-3528	1207	19	p.	p.	PROPN
fnp-3528	1207	20	;	;	PUNCT
fnp-3528	1207	21	lin	lin	PROPN
fnp-3528	1207	22	,	,	PUNCT
fnp-3528	1207	23	f.	f.	PROPN
fnp-3528	1207	24	y.	y.	PROPN
fnp-3528	1207	25	;	;	PUNCT
fnp-3528	1207	26	chen	chen	PROPN
fnp-3528	1207	27	,	,	PUNCT
fnp-3528	1207	28	s.	s.	PROPN
fnp-3528	1207	29	j.	j.	PROPN
fnp-3528	1207	30	;	;	PUNCT
fnp-3528	1207	31	tsui	tsui	PROPN
fnp-3528	1207	32	,	,	PUNCT
fnp-3528	1207	33	p.	p.	PROPN
fnp-3528	1207	34	f.	f.	PROPN
fnp-3528	1207	35	;	;	PUNCT
fnp-3528	1207	36	liu	liu	PROPN
fnp-3528	1207	37	,	,	PUNCT
fnp-3528	1207	38	y.	y.	PROPN
fnp-3528	1207	39	w.	w.	PROPN
fnp-3528	1207	40	;	;	PUNCT
fnp-3528	1207	41	lu	lu	PROPN
fnp-3528	1207	42	,	,	PUNCT
fnp-3528	1207	43	h.	h.	PROPN
fnp-3528	1207	44	j.	j.	PROPN
fnp-3528	1207	45	;	;	PUNCT
fnp-3528	1207	46	wu	wu	PROPN
fnp-3528	1207	47	,	,	PUNCT
fnp-3528	1207	48	w.	w.	PROPN
fnp-3528	1207	49	l.	l.	PROPN
fnp-3528	1207	50	;	;	PUNCT
fnp-3528	1207	51	lin	lin	PROPN
fnp-3528	1207	52	,	,	PUNCT
fnp-3528	1207	53	w.	w.	PROPN
fnp-3528	1207	54	s.	s.	PROPN
fnp-3528	1207	55	;	;	PUNCT
fnp-3528	1207	56	tsai	tsai	PROPN
fnp-3528	1207	57	,	,	PUNCT
fnp-3528	1207	58	c.	c.	PROPN
fnp-3528	1207	59	s.	s.	PROPN
fnp-3528	1207	60	;	;	PUNCT
fnp-3528	1207	61	lin	lin	PROPN
fnp-3528	1207	62	,	,	PUNCT
fnp-3528	1207	63	c.	c.	PROPN
fnp-3528	1207	64	s.	s.	PROPN
fnp-3528	1207	65	a	a	DET
fnp-3528	1207	66	chalcone	chalcone	NOUN
fnp-3528	1207	67	derivative	derivative	NOUN
fnp-3528	1207	68	,	,	PUNCT
fnp-3528	1207	69	1m-6	1m-6	NUM
fnp-3528	1207	70	,	,	PUNCT
fnp-3528	1207	71	exhibits	exhibit	VERB
fnp-3528	1207	72	atheroprotective	atheroprotective	ADJ
fnp-3528	1207	73	effects	effect	NOUN
fnp-3528	1207	74	by	by	ADP
fnp-3528	1207	75	increasing	increase	VERB
fnp-3528	1207	76	cholesterol	cholesterol	NOUN
fnp-3528	1207	77	efflux	efflux	NOUN
fnp-3528	1207	78	and	and	CCONJ
fnp-3528	1207	79	reducing	reduce	VERB
fnp-3528	1207	80	inflammation	inflammation	NOUN
fnp-3528	1207	81	-	-	PUNCT
fnp-3528	1207	82	induced	induce	VERB
fnp-3528	1207	83	endothelial	endothelial	ADJ
fnp-3528	1207	84	dysfunction	dysfunction	NOUN
fnp-3528	1207	85	.	.	PUNCT
fnp-3528	1208	1	br	br	PROPN
fnp-3528	1209	1	j	j	PROPN
fnp-3528	1209	2	pharmacol	pharmacol	PROPN
fnp-3528	1209	3	2020	2020	NUM
fnp-3528	1209	4	,	,	PUNCT
fnp-3528	1209	5	177	177	NUM
fnp-3528	1209	6	,	,	PUNCT
fnp-3528	1209	7	5375	5375	NUM
fnp-3528	1209	8	-	-	SYM
fnp-3528	1209	9	92	92	NUM
fnp-3528	1209	10	.	.	PUNCT
fnp-3528	1210	1	liu	liu	PROPN
fnp-3528	1210	2	,	,	PUNCT
fnp-3528	1210	3	x.	x.	PROPN
fnp-3528	1210	4	x.	x.	PROPN
fnp-3528	1210	5	;	;	PUNCT
fnp-3528	1210	6	zhang	zhang	PROPN
fnp-3528	1210	7	,	,	PUNCT
fnp-3528	1210	8	x.	x.	PROPN
fnp-3528	1210	9	w.	w.	PROPN
fnp-3528	1210	10	;	;	PUNCT
fnp-3528	1210	11	wang	wang	PROPN
fnp-3528	1210	12	,	,	PUNCT
fnp-3528	1210	13	k.	k.	PROPN
fnp-3528	1210	14	;	;	PUNCT
fnp-3528	1210	15	wang	wang	PROPN
fnp-3528	1210	16	,	,	PUNCT
fnp-3528	1210	17	x.	x.	PROPN
fnp-3528	1210	18	y.	y.	PROPN
fnp-3528	1210	19	;	;	PUNCT
fnp-3528	1210	20	ma	ma	PROPN
fnp-3528	1210	21	,	,	PUNCT
fnp-3528	1210	22	w.	w.	PROPN
fnp-3528	1210	23	l.	l.	PROPN
fnp-3528	1210	24	;	;	PUNCT
fnp-3528	1210	25	cao	cao	PROPN
fnp-3528	1210	26	,	,	PUNCT
fnp-3528	1210	27	w.	w.	PROPN
fnp-3528	1210	28	;	;	PUNCT
fnp-3528	1210	29	mo	mo	PROPN
fnp-3528	1210	30	,	,	PUNCT
fnp-3528	1210	31	d.	d.	PROPN
fnp-3528	1210	32	;	;	PUNCT
fnp-3528	1210	33	sun	sun	NOUN
fnp-3528	1210	34	,	,	PUNCT
fnp-3528	1210	35	y.	y.	PROPN
fnp-3528	1210	36	;	;	PUNCT
fnp-3528	1210	37	li	li	PROPN
fnp-3528	1210	38	,	,	PUNCT
fnp-3528	1210	39	x.	x.	PROPN
fnp-3528	1210	40	q.	q.	PROPN
fnp-3528	1210	41	kuwanon	kuwanon	PROPN
fnp-3528	1210	42	g	g	PROPN
fnp-3528	1210	43	attenuates	attenuate	VERB
fnp-3528	1210	44	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1210	45	by	by	ADP
fnp-3528	1210	46	upregulation	upregulation	NOUN
fnp-3528	1210	47	of	of	ADP
fnp-3528	1210	48	lxralpha	lxralpha	NOUN
fnp-3528	1210	49	-	-	PUNCT
fnp-3528	1210	50	abca1	abca1	NOUN
fnp-3528	1210	51	/	/	SYM
fnp-3528	1210	52	abcg1	abcg1	NOUN
fnp-3528	1210	53	and	and	CCONJ
fnp-3528	1210	54	inhibition	inhibition	NOUN
fnp-3528	1210	55	of	of	ADP
fnp-3528	1210	56	nfkappab	nfkappab	NOUN
fnp-3528	1210	57	activity	activity	NOUN
fnp-3528	1210	58	in	in	ADP
fnp-3528	1210	59	macrophages	macrophage	NOUN
fnp-3528	1210	60	.	.	PUNCT
fnp-3528	1211	1	toxicol	toxicol	PROPN
fnp-3528	1211	2	appl	appl	PROPN
fnp-3528	1211	3	pharmacol	pharmacol	PROPN
fnp-3528	1211	4	2018	2018	NUM
fnp-3528	1211	5	,	,	PUNCT
fnp-3528	1211	6	341	341	NUM
fnp-3528	1211	7	,	,	PUNCT
fnp-3528	1211	8	56	56	NUM
fnp-3528	1211	9	-	-	SYM
fnp-3528	1211	10	63	63	NUM
fnp-3528	1211	11	.	.	PUNCT
fnp-3528	1212	1	wang	wang	PROPN
fnp-3528	1212	2	,	,	PUNCT
fnp-3528	1212	3	g.	g.	PROPN
fnp-3528	1212	4	;	;	PUNCT
fnp-3528	1212	5	gao	gao	PROPN
fnp-3528	1212	6	,	,	PUNCT
fnp-3528	1212	7	j.	j.	PROPN
fnp-3528	1212	8	h.	h.	PROPN
fnp-3528	1212	9	;	;	PUNCT
fnp-3528	1212	10	he	he	PRON
fnp-3528	1212	11	,	,	PUNCT
fnp-3528	1212	12	l.	l.	PROPN
fnp-3528	1212	13	h.	h.	PROPN
fnp-3528	1212	14	;	;	PUNCT
fnp-3528	1212	15	yu	yu	PROPN
fnp-3528	1212	16	,	,	PUNCT
fnp-3528	1212	17	x.	x.	PROPN
fnp-3528	1212	18	h.	h.	PROPN
fnp-3528	1212	19	;	;	PUNCT
fnp-3528	1212	20	zhao	zhao	PROPN
fnp-3528	1212	21	,	,	PUNCT
fnp-3528	1212	22	z.	z.	PROPN
fnp-3528	1212	23	w.	w.	PROPN
fnp-3528	1212	24	;	;	PUNCT
fnp-3528	1212	25	zou	zou	PROPN
fnp-3528	1212	26	,	,	PUNCT
fnp-3528	1212	27	j.	j.	PROPN
fnp-3528	1212	28	;	;	PUNCT
fnp-3528	1212	29	wen	wen	PROPN
fnp-3528	1212	30	,	,	PUNCT
fnp-3528	1212	31	f.	f.	PROPN
fnp-3528	1212	32	j.	j.	PROPN
fnp-3528	1212	33	;	;	PUNCT
fnp-3528	1212	34	zhou	zhou	PROPN
fnp-3528	1212	35	,	,	PUNCT
fnp-3528	1212	36	l.	l.	PROPN
fnp-3528	1212	37	;	;	PUNCT
fnp-3528	1212	38	wan	wan	PROPN
fnp-3528	1212	39	,	,	PUNCT
fnp-3528	1212	40	x.	x.	PROPN
fnp-3528	1212	41	j.	j.	PROPN
fnp-3528	1212	42	;	;	PUNCT
fnp-3528	1212	43	tang	tang	PROPN
fnp-3528	1212	44	,	,	PUNCT
fnp-3528	1212	45	c.	c.	PROPN
fnp-3528	1212	46	k.	k.	PROPN
fnp-3528	1212	47	fargesin	fargesin	PROPN
fnp-3528	1212	48	alleviates	alleviate	VERB
fnp-3528	1212	49	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1212	50	by	by	ADP
fnp-3528	1212	51	promoting	promote	VERB
fnp-3528	1212	52	reverse	reverse	ADJ
fnp-3528	1212	53	cholesterol	cholesterol	NOUN
fnp-3528	1212	54	transport	transport	NOUN
fnp-3528	1212	55	and	and	CCONJ
fnp-3528	1212	56	reducing	reduce	VERB
fnp-3528	1212	57	inflammatory	inflammatory	ADJ
fnp-3528	1212	58	response	response	NOUN
fnp-3528	1212	59	.	.	PUNCT
fnp-3528	1213	1	biochim	biochim	PROPN
fnp-3528	1213	2	biophys	biophy	NOUN
fnp-3528	1213	3	acta	acta	PROPN
fnp-3528	1213	4	mol	mol	ADP
fnp-3528	1213	5	cell	cell	NOUN
fnp-3528	1213	6	biol	biol	NOUN
fnp-3528	1213	7	lipids	lipid	VERB
fnp-3528	1213	8	2020	2020	NUM
fnp-3528	1213	9	,	,	PUNCT
fnp-3528	1213	10	1865	1865	NUM
fnp-3528	1213	11	,	,	PUNCT
fnp-3528	1213	12	158633	158633	NUM
fnp-3528	1213	13	.	.	PUNCT
fnp-3528	1214	1	xu	xu	INTJ
fnp-3528	1214	2	,	,	PUNCT
fnp-3528	1214	3	y.	y.	PROPN
fnp-3528	1214	4	;	;	PUNCT
fnp-3528	1214	5	liu	liu	PROPN
fnp-3528	1214	6	,	,	PUNCT
fnp-3528	1214	7	q.	q.	PROPN
fnp-3528	1214	8	;	;	PUNCT
fnp-3528	1214	9	xu	xu	PROPN
fnp-3528	1214	10	,	,	PUNCT
fnp-3528	1214	11	y.	y.	PROPN
fnp-3528	1214	12	;	;	PUNCT
fnp-3528	1214	13	liu	liu	PROPN
fnp-3528	1214	14	,	,	PUNCT
fnp-3528	1214	15	c.	c.	PROPN
fnp-3528	1214	16	;	;	PUNCT
fnp-3528	1214	17	wang	wang	PROPN
fnp-3528	1214	18	,	,	PUNCT
fnp-3528	1214	19	x.	x.	PROPN
fnp-3528	1214	20	;	;	PUNCT
fnp-3528	1214	21	he	he	PRON
fnp-3528	1214	22	,	,	PUNCT
fnp-3528	1214	23	x.	x.	PROPN
fnp-3528	1214	24	;	;	PUNCT
fnp-3528	1214	25	zhu	zhu	PROPN
fnp-3528	1214	26	,	,	PUNCT
fnp-3528	1214	27	n.	n.	PROPN
fnp-3528	1214	28	;	;	PUNCT
fnp-3528	1214	29	liu	liu	PROPN
fnp-3528	1214	30	,	,	PUNCT
fnp-3528	1214	31	j.	j.	PROPN
fnp-3528	1214	32	;	;	PUNCT
fnp-3528	1214	33	wu	wu	PROPN
fnp-3528	1214	34	,	,	PUNCT
fnp-3528	1214	35	y.	y.	PROPN
fnp-3528	1214	36	;	;	PUNCT
fnp-3528	1214	37	li	li	PROPN
fnp-3528	1214	38	,	,	PUNCT
fnp-3528	1214	39	y.	y.	PROPN
fnp-3528	1214	40	;	;	PUNCT
fnp-3528	1214	41	li	li	PROPN
fnp-3528	1214	42	,	,	PUNCT
fnp-3528	1214	43	n.	n.	PROPN
fnp-3528	1214	44	;	;	PUNCT
fnp-3528	1214	45	feng	feng	PROPN
fnp-3528	1214	46	,	,	PUNCT
fnp-3528	1214	47	t.	t.	PROPN
fnp-3528	1214	48	;	;	PUNCT
fnp-3528	1214	49	lai	lai	PROPN
fnp-3528	1214	50	,	,	PUNCT
fnp-3528	1214	51	f.	f.	PROPN
fnp-3528	1214	52	;	;	PUNCT
fnp-3528	1214	53	zhang	zhang	PROPN
fnp-3528	1214	54	,	,	PUNCT
fnp-3528	1214	55	m.	m.	NOUN
fnp-3528	1214	56	;	;	PUNCT
fnp-3528	1214	57	hong	hong	PROPN
fnp-3528	1214	58	,	,	PUNCT
fnp-3528	1214	59	b.	b.	PROPN
fnp-3528	1214	60	;	;	PUNCT
fnp-3528	1214	61	jiang	jiang	PROPN
fnp-3528	1214	62	,	,	PUNCT
fnp-3528	1214	63	j.	j.	PROPN
fnp-3528	1214	64	d.	d.	PROPN
fnp-3528	1214	65	;	;	PUNCT
fnp-3528	1214	66	si	si	PROPN
fnp-3528	1214	67	,	,	PUNCT
fnp-3528	1214	68	s.	s.	PROPN
fnp-3528	1214	69	rutaecarpine	rutaecarpine	NOUN
fnp-3528	1214	70	suppresses	suppress	VERB
fnp-3528	1214	71	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1214	72	in	in	ADP
fnp-3528	1214	73	apoe-/mice	apoe-/mice	NOUN
fnp-3528	1214	74	through	through	ADP
fnp-3528	1214	75	upregulating	upregulating	ADJ
fnp-3528	1214	76	abca1	abca1	NOUN
fnp-3528	1214	77	and	and	CCONJ
fnp-3528	1214	78	sr	sr	PROPN
fnp-3528	1214	79	-	-	PUNCT
fnp-3528	1214	80	bi	bi	PROPN
fnp-3528	1214	81	within	within	ADP
fnp-3528	1214	82	rct	rct	PROPN
fnp-3528	1214	83	.	.	PUNCT
fnp-3528	1215	1	j	j	PROPN
fnp-3528	1215	2	lipid	lipid	PROPN
fnp-3528	1215	3	res	re	NOUN
fnp-3528	1215	4	2014	2014	NUM
fnp-3528	1215	5	,	,	PUNCT
fnp-3528	1215	6	55	55	NUM
fnp-3528	1215	7	,	,	PUNCT
fnp-3528	1215	8	1634	1634	NUM
fnp-3528	1215	9	-	-	SYM
fnp-3528	1215	10	47	47	NUM
fnp-3528	1215	11	.	.	PUNCT
fnp-3528	1216	1	pattanayak	pattanayak	NOUN
fnp-3528	1216	2	,	,	PUNCT
fnp-3528	1216	3	s.	s.	PROPN
fnp-3528	1216	4	p.	p.	PROPN
fnp-3528	1216	5	;	;	PUNCT
fnp-3528	1216	6	bose	bose	PROPN
fnp-3528	1216	7	,	,	PUNCT
fnp-3528	1216	8	p.	p.	PROPN
fnp-3528	1216	9	;	;	PUNCT
fnp-3528	1216	10	sunita	sunita	PROPN
fnp-3528	1216	11	,	,	PUNCT
fnp-3528	1216	12	p.	p.	NOUN
fnp-3528	1216	13	;	;	PUNCT
fnp-3528	1216	14	siddique	siddique	NOUN
fnp-3528	1216	15	,	,	PUNCT
fnp-3528	1216	16	m.	m.	NOUN
fnp-3528	1216	17	u.	u.	PROPN
fnp-3528	1216	18	m.	m.	PROPN
fnp-3528	1216	19	;	;	PUNCT
fnp-3528	1216	20	lapenna	lapenna	NOUN
fnp-3528	1216	21	,	,	PUNCT
fnp-3528	1216	22	a.	a.	NOUN
fnp-3528	1216	23	bergapten	bergapten	NOUN
fnp-3528	1216	24	inhibits	inhibit	VERB
fnp-3528	1216	25	liver	liver	NOUN
fnp-3528	1216	26	carcinogenesis	carcinogenesis	NOUN
fnp-3528	1216	27	by	by	ADP
fnp-3528	1216	28	modulating	modulate	VERB
fnp-3528	1216	29	lxr	lxr	PROPN
fnp-3528	1216	30	/	/	SYM
fnp-3528	1216	31	pi3k	pi3k	PROPN
fnp-3528	1216	32	/	/	SYM
fnp-3528	1216	33	akt	akt	PROPN
fnp-3528	1216	34	and	and	CCONJ
fnp-3528	1216	35	idol	idol	NOUN
fnp-3528	1216	36	/	/	SYM
fnp-3528	1216	37	ldlr	ldlr	ADJ
fnp-3528	1216	38	pathways	pathway	NOUN
fnp-3528	1216	39	.	.	PUNCT
fnp-3528	1217	1	biomed	biome	VERB
fnp-3528	1217	2	pharmacother	pharmacother	ADJ
fnp-3528	1217	3	2018	2018	NUM
fnp-3528	1217	4	,	,	PUNCT
fnp-3528	1217	5	108	108	NUM
fnp-3528	1217	6	,	,	PUNCT
fnp-3528	1217	7	297	297	NUM
fnp-3528	1217	8	-	-	SYM
fnp-3528	1217	9	308	308	NUM
fnp-3528	1217	10	.	.	PUNCT
fnp-3528	1218	1	shi	shi	PROPN
fnp-3528	1218	2	,	,	PUNCT
fnp-3528	1218	3	x.	x.	PROPN
fnp-3528	1218	4	;	;	PUNCT
fnp-3528	1218	5	zhang	zhang	PROPN
fnp-3528	1218	6	,	,	PUNCT
fnp-3528	1218	7	y.	y.	PROPN
fnp-3528	1218	8	;	;	PUNCT
fnp-3528	1218	9	lin	lin	PROPN
fnp-3528	1218	10	,	,	PUNCT
fnp-3528	1218	11	b.	b.	PROPN
fnp-3528	1218	12	;	;	PUNCT
fnp-3528	1218	13	zhou	zhou	PROPN
fnp-3528	1218	14	,	,	PUNCT
fnp-3528	1218	15	y.	y.	PROPN
fnp-3528	1218	16	;	;	PUNCT
fnp-3528	1218	17	suo	suo	PROPN
fnp-3528	1218	18	,	,	PUNCT
fnp-3528	1218	19	w.	w.	PROPN
fnp-3528	1218	20	;	;	PUNCT
fnp-3528	1218	21	wei	wei	PROPN
fnp-3528	1218	22	,	,	PUNCT
fnp-3528	1218	23	j.	j.	PROPN
fnp-3528	1218	24	;	;	PUNCT
fnp-3528	1218	25	zhang	zhang	PROPN
fnp-3528	1218	26	,	,	PUNCT
fnp-3528	1218	27	l.	l.	PROPN
fnp-3528	1218	28	;	;	PUNCT
fnp-3528	1218	29	lin	lin	PROPN
fnp-3528	1218	30	,	,	PUNCT
fnp-3528	1218	31	j.	j.	PROPN
fnp-3528	1218	32	;	;	PUNCT
fnp-3528	1218	33	xiao	xiao	PROPN
fnp-3528	1218	34	,	,	PUNCT
fnp-3528	1218	35	f.	f.	PROPN
fnp-3528	1218	36	;	;	PUNCT
fnp-3528	1218	37	zhao	zhao	PROPN
fnp-3528	1218	38	,	,	PUNCT
fnp-3528	1218	39	l.	l.	PROPN
fnp-3528	1218	40	;	;	PUNCT
fnp-3528	1218	41	lin	lin	PROPN
fnp-3528	1218	42	,	,	PUNCT
fnp-3528	1218	43	y.	y.	PROPN
fnp-3528	1218	44	danthron	danthron	PROPN
fnp-3528	1218	45	attenuates	attenuate	VERB
fnp-3528	1218	46	experimental	experimental	ADJ
fnp-3528	1218	47	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1218	48	by	by	ADP
fnp-3528	1218	49	targeting	target	VERB
fnp-3528	1218	50	foam	foam	NOUN
fnp-3528	1218	51	cell	cell	NOUN
fnp-3528	1218	52	formation	formation	NOUN
fnp-3528	1218	53	.	.	PUNCT
fnp-3528	1219	1	exp	exp	NOUN
fnp-3528	1219	2	physiol	physiol	PROPN
fnp-3528	1219	3	2021	2021	NUM
fnp-3528	1219	4	,	,	PUNCT
fnp-3528	1219	5	106	106	NUM
fnp-3528	1219	6	,	,	PUNCT
fnp-3528	1219	7	653	653	NUM
fnp-3528	1219	8	-	-	SYM
fnp-3528	1219	9	62	62	NUM
fnp-3528	1219	10	.	.	PUNCT
fnp-3528	1220	1	wang	wang	PROPN
fnp-3528	1220	2	,	,	PUNCT
fnp-3528	1220	3	w.	w.	PROPN
fnp-3528	1220	4	;	;	PUNCT
fnp-3528	1220	5	zhang	zhang	PROPN
fnp-3528	1220	6	,	,	PUNCT
fnp-3528	1220	7	z.	z.	PROPN
fnp-3528	1220	8	z.	z.	PROPN
fnp-3528	1220	9	;	;	PUNCT
fnp-3528	1220	10	wu	wu	PROPN
fnp-3528	1220	11	,	,	PUNCT
fnp-3528	1220	12	y.	y.	PROPN
fnp-3528	1220	13	;	;	PUNCT
fnp-3528	1220	14	wang	wang	PROPN
fnp-3528	1220	15	,	,	PUNCT
fnp-3528	1220	16	r.	r.	PROPN
fnp-3528	1220	17	q.	q.	PROPN
fnp-3528	1220	18	;	;	PUNCT
fnp-3528	1220	19	chen	chen	PROPN
fnp-3528	1220	20	,	,	PUNCT
fnp-3528	1220	21	j.	j.	PROPN
fnp-3528	1220	22	w.	w.	PROPN
fnp-3528	1220	23	;	;	PUNCT
fnp-3528	1220	24	chen	chen	PROPN
fnp-3528	1220	25	,	,	PUNCT
fnp-3528	1220	26	j.	j.	PROPN
fnp-3528	1220	27	;	;	PUNCT
fnp-3528	1220	28	zhang	zhang	PROPN
fnp-3528	1220	29	,	,	PUNCT
fnp-3528	1220	30	y.	y.	PROPN
fnp-3528	1220	31	;	;	PUNCT
fnp-3528	1220	32	chen	chen	PROPN
fnp-3528	1220	33	,	,	PUNCT
fnp-3528	1220	34	y.	y.	PROPN
fnp-3528	1220	35	j.	j.	PROPN
fnp-3528	1220	36	;	;	PUNCT
fnp-3528	1220	37	geng	geng	PROPN
fnp-3528	1220	38	,	,	PUNCT
fnp-3528	1220	39	m.	m.	NOUN
fnp-3528	1220	40	;	;	PUNCT
fnp-3528	1220	41	xu	xu	PROPN
fnp-3528	1220	42	,	,	PUNCT
fnp-3528	1220	43	z.	z.	PROPN
fnp-3528	1220	44	d.	d.	PROPN
fnp-3528	1220	45	;	;	PUNCT
fnp-3528	1220	46	dai	dai	PROPN
fnp-3528	1220	47	,	,	PUNCT
fnp-3528	1220	48	m.	m.	NOUN
fnp-3528	1220	49	;	;	PUNCT
fnp-3528	1220	50	li	li	PROPN
fnp-3528	1220	51	,	,	PUNCT
fnp-3528	1220	52	j.	j.	PROPN
fnp-3528	1220	53	h.	h.	PROPN
fnp-3528	1220	54	;	;	PUNCT
fnp-3528	1220	55	pan	pan	PROPN
fnp-3528	1220	56	,	,	PUNCT
fnp-3528	1220	57	l.	l.	PROPN
fnp-3528	1220	58	l.	l.	PROPN
fnp-3528	1220	59	(	(	PUNCT
fnp-3528	1220	60	-)-epigallocatechin-3	-)-epigallocatechin-3	ADJ
fnp-3528	1220	61	-	-	PUNCT
fnp-3528	1220	62	gallate	gallate	NOUN
fnp-3528	1220	63	ameliorates	ameliorate	NOUN
fnp-3528	1220	64	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1220	65	and	and	CCONJ
fnp-3528	1220	66	modulates	modulate	VERB
fnp-3528	1220	67	hepatic	hepatic	ADJ
fnp-3528	1220	68	lipid	lipid	NOUN
fnp-3528	1220	69	metabolic	metabolic	NOUN
fnp-3528	1220	70	gene	gene	NOUN
fnp-3528	1220	71	expression	expression	NOUN
fnp-3528	1220	72	in	in	ADP
fnp-3528	1220	73	apolipoprotein	apolipoprotein	ADJ
fnp-3528	1220	74	e	e	PROPN
fnp-3528	1220	75	knockout	knockout	NOUN
fnp-3528	1220	76	mice	mouse	NOUN
fnp-3528	1220	77	:	:	PUNCT
fnp-3528	1220	78	involvement	involvement	NOUN
fnp-3528	1220	79	of	of	ADP
fnp-3528	1220	80	ttc39b	ttc39b	PROPN
fnp-3528	1220	81	.	.	PUNCT
fnp-3528	1221	1	front	front	ADJ
fnp-3528	1221	2	pharmacol	pharmacol	PROPN
fnp-3528	1221	3	2018	2018	NUM
fnp-3528	1221	4	,	,	PUNCT
fnp-3528	1221	5	9	9	NUM
fnp-3528	1221	6	,	,	PUNCT
fnp-3528	1221	7	195	195	NUM
fnp-3528	1221	8	.	.	PUNCT
fnp-3528	1222	1	zheng	zheng	PROPN
fnp-3528	1222	2	,	,	PUNCT
fnp-3528	1222	3	s.	s.	PROPN
fnp-3528	1222	4	;	;	PUNCT
fnp-3528	1222	5	li	li	PROPN
fnp-3528	1222	6	,	,	PUNCT
fnp-3528	1222	7	l.	l.	PROPN
fnp-3528	1222	8	;	;	PUNCT
fnp-3528	1222	9	li	li	PROPN
fnp-3528	1222	10	,	,	PUNCT
fnp-3528	1222	11	n.	n.	PROPN
fnp-3528	1222	12	;	;	PUNCT
fnp-3528	1222	13	du	du	PROPN
fnp-3528	1222	14	,	,	PUNCT
fnp-3528	1222	15	y.	y.	PROPN
fnp-3528	1222	16	;	;	PUNCT
fnp-3528	1222	17	zhang	zhang	PROPN
fnp-3528	1222	18	,	,	PUNCT
fnp-3528	1222	19	n.	n.	PROPN
fnp-3528	1222	20	1	1	NUM
fnp-3528	1222	21	,	,	PUNCT
fnp-3528	1222	22	6	6	NUM
fnp-3528	1222	23	-	-	PUNCT
fnp-3528	1222	24	o	o	NOUN
fnp-3528	1222	25	,	,	PUNCT
fnp-3528	1222	26	o	o	NOUN
fnp-3528	1222	27	-	-	NOUN
fnp-3528	1222	28	diacetylbritannilactone	diacetylbritannilactone	NOUN
fnp-3528	1222	29	from	from	ADP
fnp-3528	1222	30	inula	inula	PROPN
fnp-3528	1222	31	britannica	britannica	PROPN
fnp-3528	1222	32	induces	induce	VERB
fnp-3528	1222	33	anti	anti	ADJ
fnp-3528	1222	34	-	-	ADJ
fnp-3528	1222	35	tumor	tumor	ADJ
fnp-3528	1222	36	effect	effect	NOUN
fnp-3528	1222	37	on	on	ADP
fnp-3528	1222	38	oral	oral	ADJ
fnp-3528	1222	39	squamous	squamous	ADJ
fnp-3528	1222	40	cell	cell	NOUN
fnp-3528	1222	41	carcinoma	carcinoma	NOUN
fnp-3528	1222	42	via	via	ADP
fnp-3528	1222	43	mir-1247	mir-1247	NOUN
fnp-3528	1222	44	-	-	PUNCT
fnp-3528	1222	45	3p	3p	NUM
fnp-3528	1222	46	/	/	SYM
fnp-3528	1222	47	lxralpha	lxralpha	PROPN
fnp-3528	1222	48	/	/	SYM
fnp-3528	1222	49	abca1	abca1	NOUN
fnp-3528	1222	50	signaling	signaling	NOUN
fnp-3528	1222	51	.	.	PUNCT
fnp-3528	1223	1	onco	onco	NOUN
fnp-3528	1223	2	targets	target	NOUN
fnp-3528	1223	3	ther	ther	VERB
fnp-3528	1223	4	2020	2020	NUM
fnp-3528	1223	5	,	,	PUNCT
fnp-3528	1223	6	13	13	NUM
fnp-3528	1223	7	,	,	PUNCT
fnp-3528	1223	8	11097	11097	NUM
fnp-3528	1223	9	-	-	SYM
fnp-3528	1223	10	109	109	NUM
fnp-3528	1223	11	.	.	PUNCT
fnp-3528	1224	1	mustra	mustra	PROPN
fnp-3528	1224	2	rakic	rakic	PROPN
fnp-3528	1224	3	,	,	PUNCT
fnp-3528	1224	4	j.	j.	PROPN
fnp-3528	1224	5	;	;	PUNCT
fnp-3528	1224	6	liu	liu	PROPN
fnp-3528	1224	7	,	,	PUNCT
fnp-3528	1224	8	c.	c.	PROPN
fnp-3528	1224	9	;	;	PUNCT
fnp-3528	1224	10	veeramachaneni	veeramachaneni	PROPN
fnp-3528	1224	11	,	,	PUNCT
fnp-3528	1224	12	s.	s.	PROPN
fnp-3528	1224	13	;	;	PUNCT
fnp-3528	1224	14	wu	wu	PROPN
fnp-3528	1224	15	,	,	PUNCT
fnp-3528	1224	16	d.	d.	PROPN
fnp-3528	1224	17	;	;	PUNCT
fnp-3528	1224	18	paul	paul	PROPN
fnp-3528	1224	19	,	,	PUNCT
fnp-3528	1224	20	l.	l.	PROPN
fnp-3528	1224	21	;	;	PUNCT
fnp-3528	1224	22	chen	chen	PROPN
fnp-3528	1224	23	,	,	PUNCT
fnp-3528	1224	24	c.	c.	PROPN
fnp-3528	1224	25	o.	o.	PROPN
fnp-3528	1224	26	;	;	PUNCT
fnp-3528	1224	27	ausman	ausman	NOUN
fnp-3528	1224	28	,	,	PUNCT
fnp-3528	1224	29	l.	l.	PROPN
fnp-3528	1224	30	m.	m.	PROPN
fnp-3528	1224	31	;	;	PUNCT
fnp-3528	1224	32	wang	wang	PROPN
fnp-3528	1224	33	,	,	PUNCT
fnp-3528	1224	34	x.	x.	PROPN
fnp-3528	1224	35	d.	d.	PROPN
fnp-3528	1224	36	lycopene	lycopene	PROPN
fnp-3528	1224	37	inhibits	inhibit	VERB
fnp-3528	1224	38	smoke	smoke	NOUN
fnp-3528	1224	39	-	-	PUNCT
fnp-3528	1224	40	induced	induce	VERB
fnp-3528	1224	41	chronic	chronic	ADJ
fnp-3528	1224	42	obstructive	obstructive	ADJ
fnp-3528	1224	43	pulmonary	pulmonary	ADJ
fnp-3528	1224	44	disease	disease	NOUN
fnp-3528	1224	45	and	and	CCONJ
fnp-3528	1224	46	lung	lung	NOUN
fnp-3528	1224	47	carcinogenesis	carcinogenesis	NOUN
fnp-3528	1224	48	by	by	ADP
fnp-3528	1224	49	modulating	modulate	VERB
fnp-3528	1224	50	reverse	reverse	ADJ
fnp-3528	1224	51	cholesterol	cholesterol	NOUN
fnp-3528	1224	52	transport	transport	NOUN
fnp-3528	1224	53	in	in	ADP
fnp-3528	1224	54	ferrets	ferret	NOUN
fnp-3528	1224	55	.	.	PUNCT
fnp-3528	1225	1	cancer	cancer	NOUN
fnp-3528	1225	2	prev	prev	PROPN
fnp-3528	1225	3	res	res	PROPN
fnp-3528	1225	4	(	(	PUNCT
fnp-3528	1225	5	phila	phila	PROPN
fnp-3528	1225	6	)	)	PUNCT
fnp-3528	1225	7	2019	2019	NUM
fnp-3528	1225	8	,	,	PUNCT
fnp-3528	1225	9	12	12	NUM
fnp-3528	1225	10	,	,	PUNCT
fnp-3528	1225	11	421	421	NUM
fnp-3528	1225	12	-	-	SYM
fnp-3528	1225	13	32	32	NUM
fnp-3528	1225	14	.	.	PUNCT
fnp-3528	1226	1	gwon	gwon	VERB
fnp-3528	1226	2	,	,	PUNCT
fnp-3528	1226	3	m.	m.	NOUN
fnp-3528	1226	4	h.	h.	PROPN
fnp-3528	1226	5	;	;	PUNCT
fnp-3528	1226	6	i	i	PROPN
fnp-3528	1226	7	m	m	PROPN
fnp-3528	1226	8	,	,	PUNCT
fnp-3528	1226	9	y.	y.	PROPN
fnp-3528	1226	10	s.	s.	PROPN
fnp-3528	1226	11	;	;	PUNCT
fnp-3528	1227	1	seo	seo	NOUN
fnp-3528	1227	2	,	,	PUNCT
fnp-3528	1227	3	a.	a.	PROPN
fnp-3528	1227	4	r.	r.	PROPN
fnp-3528	1227	5	;	;	PUNCT
fnp-3528	1227	6	kim	kim	PROPN
fnp-3528	1227	7	,	,	PUNCT
fnp-3528	1227	8	k.	k.	PROPN
fnp-3528	1227	9	y.	y.	PROPN
fnp-3528	1227	10	;	;	PUNCT
fnp-3528	1227	11	moon	moon	PROPN
fnp-3528	1227	12	,	,	PUNCT
fnp-3528	1227	13	h.	h.	PROPN
fnp-3528	1227	14	r.	r.	PROPN
fnp-3528	1227	15	;	;	PUNCT
fnp-3528	1227	16	yun	yun	PROPN
fnp-3528	1227	17	,	,	PUNCT
fnp-3528	1227	18	j.	j.	PROPN
fnp-3528	1227	19	m.	m.	PROPN
fnp-3528	1227	20	phenethyl	phenethyl	PROPN
fnp-3528	1227	21	isothiocyanate	isothiocyanate	PROPN
fnp-3528	1227	22	protects	protect	NOUN
fnp-3528	1227	23	against	against	ADP
fnp-3528	1227	24	high	high	ADJ
fnp-3528	1227	25	fat	fat	ADJ
fnp-3528	1227	26	/	/	SYM
fnp-3528	1227	27	cholesterol	cholesterol	NOUN
fnp-3528	1227	28	diet	diet	NOUN
fnp-3528	1227	29	-	-	PUNCT
fnp-3528	1227	30	induced	induce	VERB
fnp-3528	1227	31	obesity	obesity	NOUN
fnp-3528	1227	32	and	and	CCONJ
fnp-3528	1227	33	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1227	34	in	in	ADP
fnp-3528	1227	35	c57bl/6	c57bl/6	NOUN
fnp-3528	1227	36	mice	mouse	NOUN
fnp-3528	1227	37	.	.	PUNCT
fnp-3528	1228	1	nutrients	nutrient	NOUN
fnp-3528	1228	2	2020	2020	NUM
fnp-3528	1228	3	,	,	PUNCT
fnp-3528	1228	4	12	12	NUM
fnp-3528	1228	5	,	,	PUNCT
fnp-3528	1228	6	3657	3657	NUM
fnp-3528	1228	7	.	.	PUNCT
fnp-3528	1229	1	chen	chen	PROPN
fnp-3528	1229	2	,	,	PUNCT
fnp-3528	1229	3	y.	y.	PROPN
fnp-3528	1229	4	;	;	PUNCT
fnp-3528	1229	5	zhao	zhao	PROPN
fnp-3528	1229	6	,	,	PUNCT
fnp-3528	1229	7	y.	y.	PROPN
fnp-3528	1229	8	f.	f.	PROPN
fnp-3528	1229	9	;	;	PUNCT
fnp-3528	1229	10	yang	yang	PROPN
fnp-3528	1229	11	,	,	PUNCT
fnp-3528	1229	12	j.	j.	PROPN
fnp-3528	1229	13	;	;	PUNCT
fnp-3528	1229	14	jing	jing	PROPN
fnp-3528	1229	15	,	,	PUNCT
fnp-3528	1229	16	h.	h.	PROPN
fnp-3528	1229	17	y.	y.	PROPN
fnp-3528	1229	18	;	;	PUNCT
fnp-3528	1229	19	liang	liang	PROPN
fnp-3528	1229	20	,	,	PUNCT
fnp-3528	1229	21	w.	w.	PROPN
fnp-3528	1229	22	;	;	PUNCT
fnp-3528	1229	23	chen	chen	PROPN
fnp-3528	1229	24	,	,	PUNCT
fnp-3528	1229	25	m.	m.	NOUN
fnp-3528	1229	26	y.	y.	PROPN
fnp-3528	1229	27	;	;	PUNCT
fnp-3528	1229	28	yang	yang	PROPN
fnp-3528	1229	29	,	,	PUNCT
fnp-3528	1229	30	m.	m.	NOUN
fnp-3528	1229	31	;	;	PUNCT
fnp-3528	1229	32	wang	wang	PROPN
fnp-3528	1229	33	,	,	PUNCT
fnp-3528	1229	34	y.	y.	PROPN
fnp-3528	1229	35	;	;	PUNCT
fnp-3528	1229	36	guo	guo	PROPN
fnp-3528	1229	37	,	,	PUNCT
fnp-3528	1229	38	m.	m.	NOUN
fnp-3528	1229	39	y.	y.	NOUN
fnp-3528	1229	40	selenium	selenium	NOUN
fnp-3528	1229	41	alleviates	alleviate	VERB
fnp-3528	1229	42	lipopolysaccharide	lipopolysaccharide	ADV
fnp-3528	1229	43	-	-	PUNCT
fnp-3528	1229	44	induced	induce	VERB
fnp-3528	1229	45	endometritis	endometritis	NOUN
fnp-3528	1229	46	via	via	ADP
fnp-3528	1229	47	regulating	regulate	VERB
fnp-3528	1229	48	the	the	DET
fnp-3528	1229	49	recruitment	recruitment	NOUN
fnp-3528	1229	50	of	of	ADP
fnp-3528	1229	51	tlr4	tlr4	NOUN
fnp-3528	1229	52	into	into	ADP
fnp-3528	1229	53	lipid	lipid	ADJ
fnp-3528	1229	54	rafts	raft	NOUN
fnp-3528	1229	55	in	in	ADP
fnp-3528	1229	56	mice	mouse	NOUN
fnp-3528	1229	57	.	.	PUNCT
fnp-3528	1230	1	food	food	NOUN
fnp-3528	1230	2	funct	funct	PROPN
fnp-3528	1230	3	2020	2020	NUM
fnp-3528	1230	4	,	,	PUNCT
fnp-3528	1230	5	11	11	NUM
fnp-3528	1230	6	,	,	PUNCT
fnp-3528	1230	7	200	200	NUM
fnp-3528	1230	8	-	-	SYM
fnp-3528	1230	9	10	10	NUM
fnp-3528	1230	10	.	.	PUNCT
fnp-3528	1231	1	shen	shen	PROPN
fnp-3528	1231	2	,	,	PUNCT
fnp-3528	1231	3	d.	d.	PROPN
fnp-3528	1231	4	;	;	PUNCT
fnp-3528	1231	5	zhao	zhao	PROPN
fnp-3528	1231	6	,	,	PUNCT
fnp-3528	1231	7	d.	d.	PROPN
fnp-3528	1231	8	;	;	PUNCT
fnp-3528	1231	9	yang	yang	PROPN
fnp-3528	1231	10	,	,	PUNCT
fnp-3528	1231	11	x.	x.	PROPN
fnp-3528	1231	12	;	;	PUNCT
fnp-3528	1231	13	zhang	zhang	PROPN
fnp-3528	1231	14	,	,	PUNCT
fnp-3528	1231	15	j.	j.	PROPN
fnp-3528	1231	16	;	;	PUNCT
fnp-3528	1231	17	he	he	PRON
fnp-3528	1231	18	,	,	PUNCT
fnp-3528	1231	19	h.	h.	PROPN
fnp-3528	1231	20	;	;	PUNCT
fnp-3528	1231	21	yu	yu	PROPN
fnp-3528	1231	22	,	,	PUNCT
fnp-3528	1231	23	c.	c.	PROPN
fnp-3528	1231	24	geniposide	geniposide	NOUN
fnp-3528	1231	25	against	against	ADP
fnp-3528	1231	26	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1231	27	by	by	ADP
fnp-3528	1231	28	inhibiting	inhibit	VERB
fnp-3528	1231	29	the	the	DET
fnp-3528	1231	30	formation	formation	NOUN
fnp-3528	1231	31	of	of	ADP
fnp-3528	1231	32	foam	foam	NOUN
fnp-3528	1231	33	cell	cell	NOUN
fnp-3528	1231	34	and	and	CCONJ
fnp-3528	1231	35	lowering	lower	VERB
fnp-3528	1231	36	reverse	reverse	ADJ
fnp-3528	1231	37	lipid	lipid	NOUN
fnp-3528	1231	38	transport	transport	NOUN
fnp-3528	1231	39	via	via	ADP
fnp-3528	1231	40	p38	p38	NOUN
fnp-3528	1231	41	/	/	SYM
fnp-3528	1231	42	mapk	mapk	NOUN
fnp-3528	1231	43	signaling	signal	VERB
fnp-3528	1231	44	pathways	pathway	NOUN
fnp-3528	1231	45	.	.	PUNCT
fnp-3528	1232	1	eur	eur	PROPN
fnp-3528	1232	2	j	j	PROPN
fnp-3528	1232	3	pharmacol	pharmacol	PROPN
fnp-3528	1232	4	2019	2019	NUM
fnp-3528	1232	5	,	,	PUNCT
fnp-3528	1232	6	864	864	NUM
fnp-3528	1232	7	,	,	PUNCT
fnp-3528	1232	8	172728	172728	NUM
fnp-3528	1232	9	.	.	PUNCT
fnp-3528	1233	1	tsunemi	tsunemi	NOUN
fnp-3528	1233	2	,	,	PUNCT
fnp-3528	1233	3	a.	a.	NOUN
fnp-3528	1233	4	;	;	PUNCT
fnp-3528	1233	5	ueno	ueno	PROPN
fnp-3528	1233	6	,	,	PUNCT
fnp-3528	1233	7	t.	t.	PROPN
fnp-3528	1233	8	;	;	PUNCT
fnp-3528	1233	9	fukuda	fukuda	PROPN
fnp-3528	1233	10	,	,	PUNCT
fnp-3528	1233	11	n.	n.	PROPN
fnp-3528	1233	12	;	;	PUNCT
fnp-3528	1233	13	watanabe	watanabe	PROPN
fnp-3528	1233	14	,	,	PUNCT
fnp-3528	1233	15	t.	t.	PROPN
fnp-3528	1233	16	;	;	PUNCT
fnp-3528	1233	17	tahira	tahira	PROPN
fnp-3528	1233	18	,	,	PUNCT
fnp-3528	1233	19	k.	k.	PROPN
fnp-3528	1233	20	;	;	PUNCT
fnp-3528	1233	21	haketa	haketa	PROPN
fnp-3528	1233	22	,	,	PUNCT
fnp-3528	1233	23	a.	a.	NOUN
fnp-3528	1233	24	;	;	PUNCT
fnp-3528	1233	25	hatanaka	hatanaka	PROPN
fnp-3528	1233	26	,	,	PUNCT
fnp-3528	1233	27	y.	y.	PROPN
fnp-3528	1233	28	;	;	PUNCT
fnp-3528	1233	29	tanaka	tanaka	PROPN
fnp-3528	1233	30	,	,	PUNCT
fnp-3528	1233	31	s.	s.	PROPN
fnp-3528	1233	32	;	;	PUNCT
fnp-3528	1233	33	matsumoto	matsumoto	PROPN
fnp-3528	1233	34	,	,	PUNCT
fnp-3528	1233	35	t.	t.	PROPN
fnp-3528	1233	36	;	;	PUNCT
fnp-3528	1233	37	matsumoto	matsumoto	PROPN
fnp-3528	1233	38	,	,	PUNCT
fnp-3528	1233	39	y.	y.	PROPN
fnp-3528	1233	40	;	;	PUNCT
fnp-3528	1233	41	nagase	nagase	PROPN
fnp-3528	1233	42	,	,	PUNCT
fnp-3528	1233	43	h.	h.	PROPN
fnp-3528	1233	44	;	;	PUNCT
fnp-3528	1233	45	soma	soma	NOUN
fnp-3528	1233	46	,	,	PUNCT
fnp-3528	1233	47	m.	m.	NOUN
fnp-3528	1233	48	a	a	DET
fnp-3528	1233	49	novel	novel	ADJ
fnp-3528	1233	50	gene	gene	NOUN
fnp-3528	1233	51	regulator	regulator	NOUN
fnp-3528	1233	52	,	,	PUNCT
fnp-3528	1233	53	pyrrole	pyrrole	NOUN
fnp-3528	1233	54	-	-	PUNCT
fnp-3528	1233	55	imidazole	imidazole	NOUN
fnp-3528	1233	56	polyamide	polyamide	NOUN
fnp-3528	1233	57	targeting	targeting	NOUN
fnp-3528	1233	58	abca1	abca1	NOUN
fnp-3528	1233	59	gene	gene	NOUN
fnp-3528	1233	60	increases	increase	VERB
fnp-3528	1233	61	cholesterol	cholesterol	NOUN
fnp-3528	1233	62	efflux	efflux	VERB
fnp-3528	1233	63	from	from	ADP
fnp-3528	1233	64	macrophages	macrophage	NOUN
fnp-3528	1233	65	and	and	CCONJ
fnp-3528	1233	66	plasma	plasma	NOUN
fnp-3528	1233	67	hdl	hdl	PROPN
fnp-3528	1233	68	concentration	concentration	NOUN
fnp-3528	1233	69	.	.	PUNCT
fnp-3528	1234	1	j	j	PROPN
fnp-3528	1234	2	mol	mol	ADP
fnp-3528	1234	3	med	med	PROPN
fnp-3528	1234	4	(	(	PUNCT
fnp-3528	1234	5	berl	berl	PROPN
fnp-3528	1234	6	)	)	PUNCT
fnp-3528	1234	7	2014	2014	NUM
fnp-3528	1234	8	,	,	PUNCT
fnp-3528	1234	9	92	92	NUM
fnp-3528	1234	10	,	,	PUNCT
fnp-3528	1234	11	509	509	NUM
fnp-3528	1234	12	-	-	SYM
fnp-3528	1234	13	21	21	NUM
fnp-3528	1234	14	.	.	PUNCT
fnp-3528	1235	1	ma	ma	PROPN
fnp-3528	1235	2	,	,	PUNCT
fnp-3528	1235	3	x.	x.	PROPN
fnp-3528	1235	4	;	;	PUNCT
fnp-3528	1235	5	li	li	PROPN
fnp-3528	1235	6	,	,	PUNCT
fnp-3528	1235	7	s.	s.	PROPN
fnp-3528	1235	8	f.	f.	PROPN
fnp-3528	1235	9	;	;	PUNCT
fnp-3528	1235	10	qin	qin	PROPN
fnp-3528	1235	11	,	,	PUNCT
fnp-3528	1235	12	z.	z.	PROPN
fnp-3528	1235	13	s.	s.	PROPN
fnp-3528	1235	14	;	;	PUNCT
fnp-3528	1235	15	ye	ye	PROPN
fnp-3528	1235	16	,	,	PUNCT
fnp-3528	1235	17	j.	j.	PROPN
fnp-3528	1235	18	;	;	PUNCT
fnp-3528	1235	19	zhao	zhao	PROPN
fnp-3528	1235	20	,	,	PUNCT
fnp-3528	1235	21	z.	z.	PROPN
fnp-3528	1235	22	l.	l.	PROPN
fnp-3528	1235	23	;	;	PUNCT
fnp-3528	1235	24	fang	fang	PROPN
fnp-3528	1235	25	,	,	PUNCT
fnp-3528	1235	26	h.	h.	PROPN
fnp-3528	1235	27	h.	h.	PROPN
fnp-3528	1235	28	;	;	PUNCT
fnp-3528	1235	29	yao	yao	PROPN
fnp-3528	1235	30	,	,	PUNCT
fnp-3528	1235	31	z.	z.	PROPN
fnp-3528	1235	32	w.	w.	PROPN
fnp-3528	1235	33	;	;	PUNCT
fnp-3528	1235	34	gu	gu	PROPN
fnp-3528	1235	35	,	,	PUNCT
fnp-3528	1235	36	m.	m.	NOUN
fnp-3528	1235	37	n.	n.	PROPN
fnp-3528	1235	38	;	;	PUNCT
fnp-3528	1235	39	hu	hu	PROPN
fnp-3528	1235	40	,	,	PUNCT
fnp-3528	1235	41	y.	y.	PROPN
fnp-3528	1235	42	w.	w.	PROPN
fnp-3528	1235	43	propofol	propofol	PROPN
fnp-3528	1235	44	up	up	ADP
fnp-3528	1235	45	-	-	PUNCT
fnp-3528	1235	46	regulates	regulate	VERB
fnp-3528	1235	47	expression	expression	NOUN
fnp-3528	1235	48	of	of	ADP
fnp-3528	1235	49	abca1	abca1	NOUN
fnp-3528	1235	50	,	,	PUNCT
fnp-3528	1235	51	abcg1	abcg1	ADV
fnp-3528	1235	52	,	,	PUNCT
fnp-3528	1235	53	and	and	CCONJ
fnp-3528	1235	54	sr	sr	PROPN
fnp-3528	1235	55	-	-	PUNCT
fnp-3528	1235	56	b1	b1	PROPN
fnp-3528	1235	57	through	through	ADP
fnp-3528	1235	58	the	the	DET
fnp-3528	1235	59	ppargamma	ppargamma	PROPN
fnp-3528	1235	60	/	/	SYM
fnp-3528	1235	61	lxralpha	lxralpha	PROPN
fnp-3528	1235	62	signaling	signal	VERB
fnp-3528	1235	63	pathway	pathway	NOUN
fnp-3528	1235	64	in	in	ADP
fnp-3528	1235	65	thp-1	thp-1	PUNCT
fnp-3528	1235	66	macrophage	macrophage	NOUN
fnp-3528	1235	67	-	-	PUNCT
fnp-3528	1235	68	derived	derive	VERB
fnp-3528	1235	69	foam	foam	NOUN
fnp-3528	1235	70	cells	cell	NOUN
fnp-3528	1235	71	.	.	PUNCT
fnp-3528	1236	1	cardiovasc	cardiovasc	PROPN
fnp-3528	1236	2	pathol	pathol	VERB
fnp-3528	1236	3	2015	2015	NUM
fnp-3528	1236	4	,	,	PUNCT
fnp-3528	1236	5	24	24	NUM
fnp-3528	1236	6	,	,	PUNCT
fnp-3528	1236	7	230	230	NUM
fnp-3528	1236	8	-	-	SYM
fnp-3528	1236	9	5	5	NUM
fnp-3528	1236	10	.	.	PUNCT
fnp-3528	1237	1	belorusova	belorusova	PROPN
fnp-3528	1237	2	,	,	PUNCT
fnp-3528	1237	3	a.	a.	NOUN
fnp-3528	1237	4	y.	y.	PROPN
fnp-3528	1237	5	;	;	PUNCT
fnp-3528	1237	6	evertsson	evertsson	PROPN
fnp-3528	1237	7	,	,	PUNCT
fnp-3528	1237	8	e.	e.	PROPN
fnp-3528	1237	9	;	;	PUNCT
fnp-3528	1237	10	hovdal	hovdal	PROPN
fnp-3528	1237	11	,	,	PUNCT
fnp-3528	1237	12	d.	d.	PROPN
fnp-3528	1237	13	;	;	PUNCT
fnp-3528	1237	14	sandmark	sandmark	PROPN
fnp-3528	1237	15	,	,	PUNCT
fnp-3528	1237	16	j.	j.	PROPN
fnp-3528	1237	17	;	;	PUNCT
fnp-3528	1237	18	bratt	bratt	PROPN
fnp-3528	1237	19	,	,	PUNCT
fnp-3528	1237	20	e.	e.	PROPN
fnp-3528	1237	21	;	;	PUNCT
fnp-3528	1237	22	maxvall	maxvall	PROPN
fnp-3528	1237	23	,	,	PUNCT
fnp-3528	1237	24	i.	i.	PROPN
fnp-3528	1237	25	;	;	PUNCT
fnp-3528	1237	26	schulman	schulman	PROPN
fnp-3528	1237	27	,	,	PUNCT
fnp-3528	1237	28	i.	i.	PROPN
fnp-3528	1237	29	g.	g.	PROPN
fnp-3528	1237	30	;	;	PUNCT
fnp-3528	1237	31	akerblad	akerblad	ADJ
fnp-3528	1237	32	,	,	PUNCT
fnp-3528	1237	33	p.	p.	NOUN
fnp-3528	1237	34	;	;	PUNCT
fnp-3528	1237	35	lindstedt	lindstedt	PROPN
fnp-3528	1237	36	,	,	PUNCT
fnp-3528	1237	37	e.	e.	PROPN
fnp-3528	1237	38	l.	l.	PROPN
fnp-3528	1237	39	structural	structural	ADJ
fnp-3528	1237	40	analysis	analysis	NOUN
fnp-3528	1237	41	identifies	identify	VERB
fnp-3528	1237	42	an	an	DET
fnp-3528	1237	43	escape	escape	NOUN
fnp-3528	1237	44	route	route	NOUN
fnp-3528	1237	45	from	from	ADP
fnp-3528	1237	46	the	the	DET
fnp-3528	1237	47	adverse	adverse	ADJ
fnp-3528	1237	48	lipogenic	lipogenic	NOUN
fnp-3528	1237	49	effects	effect	NOUN
fnp-3528	1237	50	of	of	ADP
fnp-3528	1237	51	liver	liver	NOUN
fnp-3528	1237	52	x	x	NOUN
fnp-3528	1237	53	receptor	receptor	NOUN
fnp-3528	1237	54	ligands	ligand	NOUN
fnp-3528	1237	55	.	.	PUNCT
fnp-3528	1238	1	commun	commun	PROPN
fnp-3528	1238	2	biol	biol	PROPN
fnp-3528	1238	3	2019	2019	NUM
fnp-3528	1238	4	,	,	PUNCT
fnp-3528	1238	5	2	2	NUM
fnp-3528	1238	6	,	,	PUNCT
fnp-3528	1238	7	431	431	NUM
fnp-3528	1238	8	.	.	PUNCT
fnp-3528	1239	1	liu	liu	PROPN
fnp-3528	1239	2	,	,	PUNCT
fnp-3528	1239	3	h.	h.	PROPN
fnp-3528	1239	4	;	;	PUNCT
fnp-3528	1239	5	jiang	jiang	PROPN
fnp-3528	1239	6	,	,	PUNCT
fnp-3528	1239	7	x.	x.	PROPN
fnp-3528	1239	8	;	;	PUNCT
fnp-3528	1239	9	gao	gao	PROPN
fnp-3528	1239	10	,	,	PUNCT
fnp-3528	1239	11	x.	x.	PROPN
fnp-3528	1239	12	;	;	PUNCT
fnp-3528	1239	13	tian	tian	PROPN
fnp-3528	1239	14	,	,	PUNCT
fnp-3528	1239	15	w.	w.	PROPN
fnp-3528	1239	16	;	;	PUNCT
fnp-3528	1239	17	xu	xu	PROPN
fnp-3528	1239	18	,	,	PUNCT
fnp-3528	1239	19	c.	c.	PROPN
fnp-3528	1239	20	;	;	PUNCT
fnp-3528	1239	21	wang	wang	PROPN
fnp-3528	1239	22	,	,	PUNCT
fnp-3528	1239	23	r.	r.	PROPN
fnp-3528	1239	24	;	;	PUNCT
fnp-3528	1239	25	xu	xu	PROPN
fnp-3528	1239	26	,	,	PUNCT
fnp-3528	1239	27	y.	y.	PROPN
fnp-3528	1239	28	;	;	PUNCT
fnp-3528	1239	29	wei	wei	PROPN
fnp-3528	1239	30	,	,	PUNCT
fnp-3528	1239	31	l.	l.	PROPN
fnp-3528	1239	32	;	;	PUNCT
fnp-3528	1239	33	cao	cao	PROPN
fnp-3528	1239	34	,	,	PUNCT
fnp-3528	1239	35	f.	f.	PROPN
fnp-3528	1239	36	;	;	PUNCT
fnp-3528	1239	37	li	li	PROPN
fnp-3528	1239	38	,	,	PUNCT
fnp-3528	1239	39	w.	w.	NOUN
fnp-3528	1239	40	identification	identification	NOUN
fnp-3528	1239	41	of	of	ADP
fnp-3528	1239	42	n	n	CCONJ
fnp-3528	1239	43	-	-	PUNCT
fnp-3528	1239	44	benzothiazolyl-2	benzothiazolyl-2	NOUN
fnp-3528	1239	45	-	-	PUNCT
fnp-3528	1239	46	benzenesulfonamides	benzenesulfonamide	NOUN
fnp-3528	1239	47	as	as	ADP
fnp-3528	1239	48	novel	novel	ADJ
fnp-3528	1239	49	abca1	abca1	NOUN
fnp-3528	1239	50	expression	expression	NOUN
fnp-3528	1239	51	upregulators	upregulator	NOUN
fnp-3528	1239	52	.	.	PUNCT
fnp-3528	1240	1	rsc	rsc	PROPN
fnp-3528	1240	2	med	med	PROPN
fnp-3528	1240	3	chem	chem	NOUN
fnp-3528	1240	4	2020	2020	NUM
fnp-3528	1240	5	,	,	PUNCT
fnp-3528	1240	6	11	11	NUM
fnp-3528	1240	7	,	,	PUNCT
fnp-3528	1240	8	411	411	NUM
fnp-3528	1240	9	-	-	SYM
fnp-3528	1240	10	8	8	NUM
fnp-3528	1240	11	.	.	PUNCT
fnp-3528	1240	12	ren	ren	PROPN
fnp-3528	1240	13	,	,	PUNCT
fnp-3528	1240	14	g.	g.	PROPN
fnp-3528	1240	15	;	;	PUNCT
fnp-3528	1240	16	bao	bao	PROPN
fnp-3528	1240	17	,	,	PUNCT
fnp-3528	1240	18	w.	w.	PROPN
fnp-3528	1240	19	;	;	PUNCT
fnp-3528	1240	20	zeng	zeng	PROPN
fnp-3528	1240	21	,	,	PUNCT
fnp-3528	1240	22	z.	z.	PROPN
fnp-3528	1240	23	;	;	PUNCT
fnp-3528	1240	24	zhang	zhang	PROPN
fnp-3528	1240	25	,	,	PUNCT
fnp-3528	1240	26	w.	w.	PROPN
fnp-3528	1240	27	;	;	PUNCT
fnp-3528	1240	28	shang	shang	PROPN
fnp-3528	1240	29	,	,	PUNCT
fnp-3528	1240	30	c.	c.	PROPN
fnp-3528	1240	31	;	;	PUNCT
fnp-3528	1240	32	wang	wang	PROPN
fnp-3528	1240	33	,	,	PUNCT
fnp-3528	1240	34	m.	m.	NOUN
fnp-3528	1240	35	;	;	PUNCT
fnp-3528	1240	36	su	su	PROPN
fnp-3528	1240	37	,	,	PUNCT
fnp-3528	1240	38	y.	y.	PROPN
fnp-3528	1240	39	;	;	PUNCT
fnp-3528	1240	40	zhang	zhang	PROPN
fnp-3528	1240	41	,	,	PUNCT
fnp-3528	1240	42	x.	x.	PROPN
fnp-3528	1240	43	k.	k.	PROPN
fnp-3528	1240	44	;	;	PUNCT
fnp-3528	1240	45	zhou	zhou	PROPN
fnp-3528	1240	46	,	,	PUNCT
fnp-3528	1240	47	h.	h.	PROPN
fnp-3528	1240	48	retinoid	retinoid	PROPN
fnp-3528	1240	49	x	x	SYM
fnp-3528	1240	50	receptor	receptor	NOUN
fnp-3528	1240	51	alpha	alpha	NOUN
fnp-3528	1240	52	nitro	nitro	NOUN
fnp-3528	1240	53	-	-	PUNCT
fnp-3528	1240	54	ligand	ligand	NOUN
fnp-3528	1240	55	z-10	z-10	NOUN
fnp-3528	1240	56	and	and	CCONJ
fnp-3528	1240	57	its	its	PRON
fnp-3528	1240	58	optimized	optimize	VERB
fnp-3528	1240	59	derivative	derivative	ADJ
fnp-3528	1240	60	z-36	z-36	NOUN
fnp-3528	1240	61	reduce	reduce	VERB
fnp-3528	1240	62	beta	beta	NOUN
fnp-3528	1240	63	-	-	PUNCT
fnp-3528	1240	64	amyloid	amyloid	NOUN
fnp-3528	1240	65	plaques	plaque	NOUN
fnp-3528	1240	66	in	in	ADP
fnp-3528	1240	67	alzheimer	alzheimer	PROPN
fnp-3528	1240	68	's	's	PART
fnp-3528	1240	69	disease	disease	NOUN
fnp-3528	1240	70	mouse	mouse	NOUN
fnp-3528	1240	71	model	model	NOUN
fnp-3528	1240	72	.	.	PUNCT
fnp-3528	1241	1	mol	mol	ADP
fnp-3528	1241	2	pharm	pharm	PROPN
fnp-3528	1241	3	2019	2019	NUM
fnp-3528	1241	4	,	,	PUNCT
fnp-3528	1241	5	16	16	NUM
fnp-3528	1241	6	,	,	PUNCT
fnp-3528	1241	7	480	480	NUM
fnp-3528	1241	8	-	-	SYM
fnp-3528	1241	9	8	8	NUM
fnp-3528	1241	10	.	.	PUNCT
fnp-3528	1242	1	li	li	PROPN
fnp-3528	1242	2	,	,	PUNCT
fnp-3528	1242	3	y.	y.	PROPN
fnp-3528	1242	4	;	;	PUNCT
fnp-3528	1242	5	feng	feng	PROPN
fnp-3528	1242	6	,	,	PUNCT
fnp-3528	1242	7	t.	t.	PROPN
fnp-3528	1242	8	;	;	PUNCT
fnp-3528	1242	9	liu	liu	PROPN
fnp-3528	1242	10	,	,	PUNCT
fnp-3528	1242	11	p.	p.	PROPN
fnp-3528	1242	12	;	;	PUNCT
fnp-3528	1242	13	liu	liu	PROPN
fnp-3528	1242	14	,	,	PUNCT
fnp-3528	1242	15	c.	c.	PROPN
fnp-3528	1242	16	;	;	PUNCT
fnp-3528	1242	17	wang	wang	PROPN
fnp-3528	1242	18	,	,	PUNCT
fnp-3528	1242	19	x.	x.	PROPN
fnp-3528	1242	20	;	;	PUNCT
fnp-3528	1242	21	li	li	PROPN
fnp-3528	1242	22	,	,	PUNCT
fnp-3528	1242	23	d.	d.	PROPN
fnp-3528	1242	24	;	;	PUNCT
fnp-3528	1242	25	li	li	PROPN
fnp-3528	1242	26	,	,	PUNCT
fnp-3528	1242	27	n.	n.	PROPN
fnp-3528	1242	28	;	;	PUNCT
fnp-3528	1242	29	chen	chen	PROPN
fnp-3528	1242	30	,	,	PUNCT
fnp-3528	1242	31	m.	m.	NOUN
fnp-3528	1242	32	;	;	PUNCT
fnp-3528	1242	33	xu	xu	INTJ
fnp-3528	1242	34	,	,	PUNCT
fnp-3528	1242	35	y.	y.	PROPN
fnp-3528	1242	36	;	;	PUNCT
fnp-3528	1242	37	si	si	PROPN
fnp-3528	1242	38	,	,	PUNCT
fnp-3528	1242	39	s.	s.	PROPN
fnp-3528	1242	40	optimization	optimization	NOUN
fnp-3528	1242	41	of	of	ADP
fnp-3528	1242	42	rutaecarpine	rutaecarpine	NOUN
fnp-3528	1242	43	as	as	ADP
fnp-3528	1242	44	abca1	abca1	NOUN
fnp-3528	1242	45	up	up	ADP
fnp-3528	1242	46	-	-	PUNCT
fnp-3528	1242	47	regulator	regulator	NOUN
fnp-3528	1242	48	for	for	ADP
fnp-3528	1242	49	treating	treat	VERB
fnp-3528	1242	50	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1242	51	.	.	PUNCT
fnp-3528	1243	1	acs	acs	PROPN
fnp-3528	1243	2	med	med	PROPN
fnp-3528	1243	3	chem	chem	NOUN
fnp-3528	1243	4	lett	lett	PROPN
fnp-3528	1243	5	2014	2014	NUM
fnp-3528	1243	6	,	,	PUNCT
fnp-3528	1243	7	5	5	NUM
fnp-3528	1243	8	,	,	PUNCT
fnp-3528	1243	9	884	884	NUM
fnp-3528	1243	10	-	-	SYM
fnp-3528	1243	11	8	8	NUM
fnp-3528	1243	12	.	.	PUNCT
fnp-3528	1244	1	singh	singh	PROPN
fnp-3528	1244	2	,	,	PUNCT
fnp-3528	1244	3	s.	s.	PROPN
fnp-3528	1244	4	b.	b.	PROPN
fnp-3528	1244	5	;	;	PUNCT
fnp-3528	1244	6	ondeyka	ondeyka	PROPN
fnp-3528	1244	7	,	,	PUNCT
fnp-3528	1244	8	j.	j.	PROPN
fnp-3528	1244	9	g.	g.	PROPN
fnp-3528	1244	10	;	;	PUNCT
fnp-3528	1244	11	liu	liu	PROPN
fnp-3528	1244	12	,	,	PUNCT
fnp-3528	1244	13	w.	w.	PROPN
fnp-3528	1244	14	;	;	PUNCT
fnp-3528	1244	15	chen	chen	PROPN
fnp-3528	1244	16	,	,	PUNCT
fnp-3528	1244	17	s.	s.	PROPN
fnp-3528	1244	18	;	;	PUNCT
fnp-3528	1244	19	chen	chen	PROPN
fnp-3528	1244	20	,	,	PUNCT
fnp-3528	1244	21	t.	t.	PROPN
fnp-3528	1244	22	s.	s.	PROPN
fnp-3528	1244	23	;	;	PUNCT
fnp-3528	1244	24	li	li	PROPN
fnp-3528	1244	25	,	,	PUNCT
fnp-3528	1244	26	x.	x.	NOUN
fnp-3528	1244	27	;	;	PUNCT
fnp-3528	1244	28	bouffard	bouffard	ADV
fnp-3528	1244	29	,	,	PUNCT
fnp-3528	1244	30	a.	a.	NOUN
fnp-3528	1244	31	;	;	PUNCT
fnp-3528	1244	32	dropinski	dropinski	PROPN
fnp-3528	1244	33	,	,	PUNCT
fnp-3528	1244	34	j.	j.	PROPN
fnp-3528	1244	35	;	;	PUNCT
fnp-3528	1244	36	jones	jones	PROPN
fnp-3528	1244	37	,	,	PUNCT
fnp-3528	1244	38	a.	a.	PROPN
fnp-3528	1244	39	b.	b.	PROPN
fnp-3528	1244	40	;	;	PUNCT
fnp-3528	1244	41	mccormick	mccormick	PROPN
fnp-3528	1244	42	,	,	PUNCT
fnp-3528	1244	43	s.	s.	PROPN
fnp-3528	1244	44	;	;	PUNCT
fnp-3528	1244	45	hayes	hayes	PROPN
fnp-3528	1244	46	,	,	PUNCT
fnp-3528	1244	47	n.	n.	PROPN
fnp-3528	1244	48	;	;	PUNCT
fnp-3528	1244	49	wang	wang	PROPN
fnp-3528	1244	50	,	,	PUNCT
fnp-3528	1244	51	j.	j.	PROPN
fnp-3528	1244	52	;	;	PUNCT
fnp-3528	1244	53	sharma	sharma	PROPN
fnp-3528	1244	54	,	,	PUNCT
fnp-3528	1244	55	n.	n.	NOUN
fnp-3528	1244	56	;	;	PUNCT
fnp-3528	1244	57	macnaul	macnaul	PROPN
fnp-3528	1244	58	,	,	PUNCT
fnp-3528	1244	59	k.	k.	PROPN
fnp-3528	1244	60	;	;	PUNCT
fnp-3528	1244	61	hernandez	hernandez	PROPN
fnp-3528	1244	62	,	,	PUNCT
fnp-3528	1244	63	m.	m.	NOUN
fnp-3528	1244	64	;	;	PUNCT
fnp-3528	1244	65	chao	chao	PROPN
fnp-3528	1244	66	,	,	PUNCT
fnp-3528	1244	67	y.	y.	PROPN
fnp-3528	1244	68	s.	s.	PROPN
fnp-3528	1244	69	;	;	PUNCT
fnp-3528	1244	70	baffic	baffic	PROPN
fnp-3528	1244	71	,	,	PUNCT
fnp-3528	1244	72	j.	j.	PROPN
fnp-3528	1244	73	;	;	PUNCT
fnp-3528	1244	74	lam	lam	PROPN
fnp-3528	1244	75	,	,	PUNCT
fnp-3528	1244	76	m.	m.	PROPN
fnp-3528	1244	77	h.	h.	PROPN
fnp-3528	1244	78	;	;	PUNCT
fnp-3528	1244	79	burton	burton	PROPN
fnp-3528	1244	80	,	,	PUNCT
fnp-3528	1244	81	c.	c.	PROPN
fnp-3528	1244	82	;	;	PUNCT
fnp-3528	1244	83	sparrow	sparrow	NOUN
fnp-3528	1244	84	,	,	PUNCT
fnp-3528	1244	85	c.	c.	PROPN
fnp-3528	1244	86	p.	p.	PROPN
fnp-3528	1244	87	;	;	PUNCT
fnp-3528	1245	1	menke	menke	NOUN
fnp-3528	1245	2	,	,	PUNCT
fnp-3528	1245	3	j.	j.	PROPN
fnp-3528	1245	4	g.	g.	PROPN
fnp-3528	1245	5	discovery	discovery	PROPN
fnp-3528	1245	6	and	and	CCONJ
fnp-3528	1245	7	development	development	NOUN
fnp-3528	1245	8	of	of	ADP
fnp-3528	1245	9	dimeric	dimeric	ADJ
fnp-3528	1245	10	podocarpic	podocarpic	NOUN
fnp-3528	1245	11	acid	acid	NOUN
fnp-3528	1245	12	leads	lead	VERB
fnp-3528	1245	13	as	as	ADP
fnp-3528	1245	14	potent	potent	ADJ
fnp-3528	1245	15	agonists	agonist	NOUN
fnp-3528	1245	16	of	of	ADP
fnp-3528	1245	17	liver	liver	NOUN
fnp-3528	1245	18	x	x	NOUN
fnp-3528	1245	19	receptor	receptor	NOUN
fnp-3528	1245	20	with	with	ADP
fnp-3528	1245	21	hdl	hdl	PROPN
fnp-3528	1245	22	cholesterol	cholesterol	PROPN
fnp-3528	1245	23	raising	raise	VERB
fnp-3528	1245	24	activity	activity	NOUN
fnp-3528	1245	25	in	in	ADP
fnp-3528	1245	26	mice	mouse	NOUN
fnp-3528	1245	27	and	and	CCONJ
fnp-3528	1245	28	hamsters	hamster	NOUN
fnp-3528	1245	29	.	.	PUNCT
fnp-3528	1246	1	bioorg	bioorg	PROPN
fnp-3528	1246	2	med	med	PROPN
fnp-3528	1246	3	chem	chem	NOUN
fnp-3528	1246	4	lett	lett	NOUN
fnp-3528	1246	5	2005	2005	NUM
fnp-3528	1246	6	,	,	PUNCT
fnp-3528	1246	7	15	15	NUM
fnp-3528	1246	8	,	,	PUNCT
fnp-3528	1246	9	2824	2824	NUM
fnp-3528	1246	10	-	-	SYM
fnp-3528	1246	11	8	8	NUM
fnp-3528	1246	12	.	.	PUNCT
fnp-3528	1247	1	boehm	boehm	PROPN
fnp-3528	1247	2	-	-	PUNCT
fnp-3528	1247	3	cagan	cagan	PROPN
fnp-3528	1247	4	,	,	PUNCT
fnp-3528	1247	5	a.	a.	NOUN
fnp-3528	1247	6	;	;	PUNCT
fnp-3528	1247	7	michaelson	michaelson	PROPN
fnp-3528	1247	8	,	,	PUNCT
fnp-3528	1247	9	d.	d.	PROPN
fnp-3528	1247	10	m.	m.	PROPN
fnp-3528	1247	11	reversal	reversal	NOUN
fnp-3528	1247	12	of	of	ADP
fnp-3528	1247	13	apoe4	apoe4	ADJ
fnp-3528	1247	14	-	-	PUNCT
fnp-3528	1247	15	driven	drive	VERB
fnp-3528	1247	16	brain	brain	NOUN
fnp-3528	1247	17	pathology	pathology	NOUN
fnp-3528	1247	18	and	and	CCONJ
fnp-3528	1247	19	behavioral	behavioral	ADJ
fnp-3528	1247	20	deficits	deficit	NOUN
fnp-3528	1247	21	by	by	ADP
fnp-3528	1247	22	bexarotene	bexarotene	NOUN
fnp-3528	1247	23	.	.	PUNCT
fnp-3528	1248	1	j	j	PROPN
fnp-3528	1248	2	neurosci	neurosci	PROPN
fnp-3528	1248	3	2014	2014	NUM
fnp-3528	1248	4	,	,	PUNCT
fnp-3528	1248	5	34	34	NUM
fnp-3528	1248	6	,	,	PUNCT
fnp-3528	1248	7	7293	7293	NUM
fnp-3528	1248	8	-	-	SYM
fnp-3528	1248	9	301	301	NUM
fnp-3528	1248	10	.	.	PUNCT
fnp-3528	1249	1	niesor	niesor	PROPN
fnp-3528	1249	2	,	,	PUNCT
fnp-3528	1249	3	e.	e.	PROPN
fnp-3528	1249	4	j.	j.	PROPN
fnp-3528	1249	5	;	;	PUNCT
fnp-3528	1249	6	schwartz	schwartz	PROPN
fnp-3528	1249	7	,	,	PUNCT
fnp-3528	1249	8	g.	g.	PROPN
fnp-3528	1249	9	g.	g.	PROPN
fnp-3528	1249	10	;	;	PUNCT
fnp-3528	1249	11	perez	perez	PROPN
fnp-3528	1249	12	,	,	PUNCT
fnp-3528	1249	13	a.	a.	NOUN
fnp-3528	1249	14	;	;	PUNCT
fnp-3528	1249	15	stauffer	stauffer	PROPN
fnp-3528	1249	16	,	,	PUNCT
fnp-3528	1249	17	a.	a.	NOUN
fnp-3528	1249	18	;	;	PUNCT
fnp-3528	1249	19	durrwell	durrwell	PROPN
fnp-3528	1249	20	,	,	PUNCT
fnp-3528	1249	21	a.	a.	NOUN
fnp-3528	1249	22	;	;	PUNCT
fnp-3528	1249	23	bucklar	bucklar	PROPN
fnp-3528	1249	24	-	-	PUNCT
fnp-3528	1249	25	suchankova	suchankova	NOUN
fnp-3528	1249	26	,	,	PUNCT
fnp-3528	1249	27	g.	g.	PROPN
fnp-3528	1249	28	;	;	PUNCT
fnp-3528	1249	29	benghozi	benghozi	PROPN
fnp-3528	1249	30	,	,	PUNCT
fnp-3528	1249	31	r.	r.	PROPN
fnp-3528	1249	32	;	;	PUNCT
fnp-3528	1249	33	abt	abt	ADV
fnp-3528	1249	34	,	,	PUNCT
fnp-3528	1249	35	m.	m.	NOUN
fnp-3528	1249	36	;	;	PUNCT
fnp-3528	1249	37	kallend	kallend	PROPN
fnp-3528	1249	38	,	,	PUNCT
fnp-3528	1249	39	d.	d.	PROPN
fnp-3528	1249	40	statin	statin	PROPN
fnp-3528	1249	41	-	-	PUNCT
fnp-3528	1249	42	induced	induce	VERB
fnp-3528	1249	43	decrease	decrease	NOUN
fnp-3528	1249	44	in	in	ADP
fnp-3528	1249	45	atp	atp	NOUN
fnp-3528	1249	46	-	-	PUNCT
fnp-3528	1249	47	binding	bind	VERB
fnp-3528	1249	48	cassette	cassette	NOUN
fnp-3528	1249	49	transporter	transporter	NOUN
fnp-3528	1249	50	a1	a1	NOUN
fnp-3528	1249	51	expression	expression	NOUN
fnp-3528	1249	52	via	via	ADP
fnp-3528	1249	53	microrna33	microrna33	NOUN
fnp-3528	1249	54	induction	induction	NOUN
fnp-3528	1249	55	may	may	AUX
fnp-3528	1249	56	counteract	counteract	VERB
fnp-3528	1249	57	cholesterol	cholesterol	NOUN
fnp-3528	1249	58	efflux	efflux	NOUN
fnp-3528	1249	59	to	to	ADP
fnp-3528	1249	60	high	high	ADJ
fnp-3528	1249	61	-	-	PUNCT
fnp-3528	1249	62	density	density	NOUN
fnp-3528	1249	63	lipoprotein	lipoprotein	NOUN
fnp-3528	1249	64	.	.	PUNCT
fnp-3528	1250	1	cardiovasc	cardiovasc	PROPN
fnp-3528	1250	2	drugs	drug	NOUN
fnp-3528	1250	3	ther	ther	PROPN
fnp-3528	1250	4	2015	2015	NUM
fnp-3528	1250	5	,	,	PUNCT
fnp-3528	1250	6	29	29	NUM
fnp-3528	1250	7	,	,	PUNCT
fnp-3528	1250	8	7	7	NUM
fnp-3528	1250	9	-	-	SYM
fnp-3528	1250	10	14	14	NUM
fnp-3528	1250	11	.	.	PUNCT
fnp-3528	1251	1	allen	allen	PROPN
fnp-3528	1251	2	,	,	PUNCT
fnp-3528	1251	3	a.	a.	NOUN
fnp-3528	1251	4	m.	m.	NOUN
fnp-3528	1251	5	;	;	PUNCT
fnp-3528	1251	6	graham	graham	PROPN
fnp-3528	1251	7	,	,	PUNCT
fnp-3528	1251	8	a.	a.	PROPN
fnp-3528	1251	9	mitochondrial	mitochondrial	ADJ
fnp-3528	1251	10	function	function	NOUN
fnp-3528	1251	11	is	be	AUX
fnp-3528	1251	12	involved	involve	VERB
fnp-3528	1251	13	in	in	ADP
fnp-3528	1251	14	regulation	regulation	NOUN
fnp-3528	1251	15	of	of	ADP
fnp-3528	1251	16	cholesterol	cholesterol	NOUN
fnp-3528	1251	17	efflux	efflux	VERB
fnp-3528	1251	18	to	to	PART
fnp-3528	1251	19	apolipoprotein	apolipoprotein	VERB
fnp-3528	1251	20	(	(	PUNCT
fnp-3528	1251	21	apo)a	apo)a	NOUN
fnp-3528	1251	22	-	-	NOUN
fnp-3528	1251	23	i	i	PRON
fnp-3528	1251	24	from	from	ADP
fnp-3528	1251	25	murine	murine	ADJ
fnp-3528	1251	26	raw	raw	ADJ
fnp-3528	1251	27	264.7	264.7	NUM
fnp-3528	1251	28	macrophages	macrophage	NOUN
fnp-3528	1251	29	.	.	PUNCT
fnp-3528	1252	1	lipids	lipids	ADP
fnp-3528	1252	2	health	health	NOUN
fnp-3528	1252	3	dis	dis	PROPN
fnp-3528	1252	4	2012	2012	NUM
fnp-3528	1252	5	,	,	PUNCT
fnp-3528	1252	6	11	11	NUM
fnp-3528	1252	7	,	,	PUNCT
fnp-3528	1252	8	169	169	NUM
fnp-3528	1252	9	.	.	PUNCT
fnp-3528	1252	10	abe	abe	PROPN
fnp-3528	1252	11	-	-	PUNCT
fnp-3528	1252	12	dohmae	dohmae	PROPN
fnp-3528	1252	13	,	,	PUNCT
fnp-3528	1252	14	s.	s.	PROPN
fnp-3528	1252	15	;	;	PUNCT
fnp-3528	1252	16	ikeda	ikeda	PROPN
fnp-3528	1252	17	,	,	PUNCT
fnp-3528	1252	18	y.	y.	PROPN
fnp-3528	1252	19	;	;	PUNCT
fnp-3528	1252	20	matsuo	matsuo	PROPN
fnp-3528	1252	21	,	,	PUNCT
fnp-3528	1252	22	m.	m.	NOUN
fnp-3528	1252	23	;	;	PUNCT
fnp-3528	1252	24	hayashi	hayashi	PROPN
fnp-3528	1252	25	,	,	PUNCT
fnp-3528	1252	26	m.	m.	NOUN
fnp-3528	1252	27	;	;	PUNCT
fnp-3528	1252	28	okuhira	okuhira	PROPN
fnp-3528	1252	29	,	,	PUNCT
fnp-3528	1252	30	k.	k.	PROPN
fnp-3528	1252	31	;	;	PUNCT
fnp-3528	1252	32	ueda	ueda	PROPN
fnp-3528	1252	33	,	,	PUNCT
fnp-3528	1252	34	k.	k.	PROPN
fnp-3528	1252	35	;	;	PUNCT
fnp-3528	1252	36	yokoyama	yokoyama	PROPN
fnp-3528	1252	37	,	,	PUNCT
fnp-3528	1252	38	s.	s.	PROPN
fnp-3528	1252	39	human	human	PROPN
fnp-3528	1252	40	abca7	abca7	PROPN
fnp-3528	1252	41	supports	support	VERB
fnp-3528	1252	42	apolipoprotein	apolipoprotein	ADJ
fnp-3528	1252	43	-	-	PUNCT
fnp-3528	1252	44	mediated	mediate	VERB
fnp-3528	1252	45	release	release	NOUN
fnp-3528	1252	46	of	of	ADP
fnp-3528	1252	47	cellular	cellular	ADJ
fnp-3528	1252	48	cholesterol	cholesterol	NOUN
fnp-3528	1252	49	and	and	CCONJ
fnp-3528	1252	50	phospholipid	phospholipid	NOUN
fnp-3528	1252	51	to	to	PART
fnp-3528	1252	52	generate	generate	VERB
fnp-3528	1252	53	high	high	ADJ
fnp-3528	1252	54	density	density	NOUN
fnp-3528	1252	55	lipoprotein	lipoprotein	ADJ
fnp-3528	1252	56	.	.	PUNCT
fnp-3528	1253	1	j	j	PROPN
fnp-3528	1253	2	biol	biol	PROPN
fnp-3528	1253	3	chem	chem	NOUN
fnp-3528	1253	4	2004	2004	NUM
fnp-3528	1253	5	,	,	PUNCT
fnp-3528	1253	6	279	279	NUM
fnp-3528	1253	7	,	,	PUNCT
fnp-3528	1253	8	604	604	NUM
fnp-3528	1253	9	-	-	SYM
fnp-3528	1253	10	11	11	NUM
fnp-3528	1253	11	.	.	PUNCT
fnp-3528	1254	1	abe	abe	PROPN
fnp-3528	1254	2	-	-	PUNCT
fnp-3528	1254	3	dohmae	dohmae	PROPN
fnp-3528	1254	4	,	,	PUNCT
fnp-3528	1254	5	s.	s.	PROPN
fnp-3528	1254	6	;	;	PUNCT
fnp-3528	1254	7	suzuki	suzuki	PROPN
fnp-3528	1254	8	,	,	PUNCT
fnp-3528	1254	9	s.	s.	PROPN
fnp-3528	1254	10	;	;	PUNCT
fnp-3528	1254	11	wada	wada	PROPN
fnp-3528	1254	12	,	,	PUNCT
fnp-3528	1254	13	y.	y.	PROPN
fnp-3528	1254	14	;	;	PUNCT
fnp-3528	1254	15	aburatani	aburatani	PROPN
fnp-3528	1254	16	,	,	PUNCT
fnp-3528	1254	17	h.	h.	PROPN
fnp-3528	1254	18	;	;	PUNCT
fnp-3528	1254	19	vance	vance	PROPN
fnp-3528	1254	20	,	,	PUNCT
fnp-3528	1254	21	d.	d.	PROPN
fnp-3528	1254	22	e.	e.	PROPN
fnp-3528	1254	23	;	;	PUNCT
fnp-3528	1254	24	yokoyama	yokoyama	PROPN
fnp-3528	1254	25	,	,	PUNCT
fnp-3528	1254	26	s.	s.	PROPN
fnp-3528	1254	27	characterization	characterization	NOUN
fnp-3528	1254	28	of	of	ADP
fnp-3528	1254	29	apolipoprotein	apolipoprotein	ADV
fnp-3528	1254	30	-	-	PUNCT
fnp-3528	1254	31	mediated	mediate	VERB
fnp-3528	1254	32	hdl	hdl	NOUN
fnp-3528	1254	33	generation	generation	NOUN
fnp-3528	1254	34	induced	induce	VERB
fnp-3528	1254	35	by	by	ADP
fnp-3528	1254	36	camp	camp	NOUN
fnp-3528	1254	37	in	in	ADP
fnp-3528	1254	38	a	a	DET
fnp-3528	1254	39	murine	murine	ADJ
fnp-3528	1254	40	macrophage	macrophage	ADJ
fnp-3528	1254	41	cell	cell	NOUN
fnp-3528	1254	42	line	line	NOUN
fnp-3528	1254	43	.	.	PUNCT
fnp-3528	1255	1	biochemistry	biochemistry	NOUN
fnp-3528	1255	2	2000	2000	NUM
fnp-3528	1255	3	,	,	PUNCT
fnp-3528	1255	4	39	39	NUM
fnp-3528	1255	5	,	,	PUNCT
fnp-3528	1255	6	11092	11092	NUM
fnp-3528	1255	7	-	-	SYM
fnp-3528	1255	8	9	9	NUM
fnp-3528	1255	9	.	.	X
fnp-3528	1256	1	zhong	zhong	PROPN
fnp-3528	1256	2	,	,	PUNCT
fnp-3528	1256	3	y.	y.	PROPN
fnp-3528	1256	4	;	;	PUNCT
fnp-3528	1256	5	liu	liu	PROPN
fnp-3528	1256	6	,	,	PUNCT
fnp-3528	1256	7	c.	c.	PROPN
fnp-3528	1256	8	;	;	PUNCT
fnp-3528	1256	9	feng	feng	PROPN
fnp-3528	1256	10	,	,	PUNCT
fnp-3528	1256	11	j.	j.	PROPN
fnp-3528	1256	12	;	;	PUNCT
fnp-3528	1256	13	li	li	PROPN
fnp-3528	1256	14	,	,	PUNCT
fnp-3528	1256	15	j.	j.	PROPN
fnp-3528	1256	16	f.	f.	PROPN
fnp-3528	1256	17	;	;	PUNCT
fnp-3528	1256	18	fan	fan	PROPN
fnp-3528	1256	19	,	,	PUNCT
fnp-3528	1256	20	z.	z.	PROPN
fnp-3528	1256	21	c.	c.	PROPN
fnp-3528	1256	22	curcumin	curcumin	PROPN
fnp-3528	1256	23	affects	affect	VERB
fnp-3528	1256	24	ox	ox	ADJ
fnp-3528	1256	25	-	-	ADJ
fnp-3528	1256	26	ldl	ldl	ADJ
fnp-3528	1256	27	-	-	PUNCT
fnp-3528	1256	28	induced	induced	ADJ
fnp-3528	1256	29	il-6	il-6	NOUN
fnp-3528	1256	30	,	,	PUNCT
fnp-3528	1256	31	tnf	tnf	PROPN
fnp-3528	1256	32	-	-	PUNCT
fnp-3528	1256	33	alpha	alpha	NOUN
fnp-3528	1256	34	,	,	PUNCT
fnp-3528	1256	35	mcp-1	mcp-1	NOUN
fnp-3528	1256	36	secretion	secretion	NOUN
fnp-3528	1256	37	and	and	CCONJ
fnp-3528	1256	38	cholesterol	cholesterol	NOUN
fnp-3528	1256	39	efflux	efflux	VERB
fnp-3528	1256	40	in	in	ADP
fnp-3528	1256	41	thp-1	thp-1	ADP
fnp-3528	1256	42	cells	cell	NOUN
fnp-3528	1256	43	by	by	ADP
fnp-3528	1256	44	suppressing	suppress	VERB
fnp-3528	1256	45	the	the	DET
fnp-3528	1256	46	tlr4	tlr4	NOUN
fnp-3528	1256	47	/	/	SYM
fnp-3528	1256	48	nf	nf	NOUN
fnp-3528	1256	49	-	-	PUNCT
fnp-3528	1256	50	kappab	kappab	NOUN
fnp-3528	1256	51	/	/	SYM
fnp-3528	1256	52	mir33a	mir33a	NOUN
fnp-3528	1256	53	signaling	signal	VERB
fnp-3528	1256	54	pathway	pathway	NOUN
fnp-3528	1256	55	.	.	PUNCT
fnp-3528	1257	1	exp	exp	NOUN
fnp-3528	1257	2	ther	ther	PROPN
fnp-3528	1257	3	med	med	PROPN
fnp-3528	1257	4	2020	2020	NUM
fnp-3528	1257	5	,	,	PUNCT
fnp-3528	1257	6	20	20	NUM
fnp-3528	1257	7	,	,	PUNCT
fnp-3528	1257	8	1856	1856	NUM
fnp-3528	1257	9	-	-	SYM
fnp-3528	1257	10	70	70	NUM
fnp-3528	1257	11	.	.	PUNCT
fnp-3528	1258	1	wang	wang	PROPN
fnp-3528	1258	2	,	,	PUNCT
fnp-3528	1258	3	y.	y.	PROPN
fnp-3528	1258	4	;	;	PUNCT
fnp-3528	1258	5	wen	wen	PROPN
fnp-3528	1258	6	,	,	PUNCT
fnp-3528	1258	7	y.	y.	PROPN
fnp-3528	1258	8	;	;	PUNCT
fnp-3528	1258	9	xiao	xiao	PROPN
fnp-3528	1258	10	,	,	PUNCT
fnp-3528	1258	11	p.	p.	NOUN
fnp-3528	1258	12	;	;	PUNCT
fnp-3528	1258	13	sun	sun	PROPN
fnp-3528	1258	14	,	,	PUNCT
fnp-3528	1258	15	j.	j.	PROPN
fnp-3528	1258	16	;	;	PUNCT
fnp-3528	1258	17	chen	chen	PROPN
fnp-3528	1258	18	,	,	PUNCT
fnp-3528	1258	19	m.	m.	NOUN
fnp-3528	1258	20	;	;	PUNCT
fnp-3528	1258	21	gu	gu	PROPN
fnp-3528	1258	22	,	,	PUNCT
fnp-3528	1258	23	c.	c.	PROPN
fnp-3528	1258	24	;	;	PUNCT
fnp-3528	1258	25	kong	kong	PROPN
fnp-3528	1258	26	,	,	PUNCT
fnp-3528	1258	27	y.	y.	PROPN
fnp-3528	1258	28	;	;	PUNCT
fnp-3528	1258	29	gu	gu	PROPN
fnp-3528	1258	30	,	,	PUNCT
fnp-3528	1258	31	a.	a.	PROPN
fnp-3528	1258	32	;	;	PUNCT
fnp-3528	1258	33	zhang	zhang	PROPN
fnp-3528	1258	34	,	,	PUNCT
fnp-3528	1258	35	j.	j.	PROPN
fnp-3528	1258	36	;	;	PUNCT
fnp-3528	1258	37	wang	wang	PROPN
fnp-3528	1258	38	,	,	PUNCT
fnp-3528	1258	39	y.	y.	PROPN
fnp-3528	1258	40	di	di	PROPN
fnp-3528	1258	41	-	-	PUNCT
fnp-3528	1258	42	n	n	CCONJ
fnp-3528	1258	43	-	-	PUNCT
fnp-3528	1258	44	butyl	butyl	NOUN
fnp-3528	1258	45	phthalate	phthalate	NOUN
fnp-3528	1258	46	promotes	promote	VERB
fnp-3528	1258	47	lipid	lipid	ADJ
fnp-3528	1258	48	accumulation	accumulation	NOUN
fnp-3528	1258	49	via	via	ADP
fnp-3528	1258	50	the	the	DET
fnp-3528	1258	51	mir200c-5p	mir200c-5p	NOUN
fnp-3528	1258	52	-	-	PUNCT
fnp-3528	1258	53	abca1	abca1	NOUN
fnp-3528	1258	54	pathway	pathway	NOUN
fnp-3528	1258	55	in	in	ADP
fnp-3528	1258	56	thp-1	thp-1	ADP
fnp-3528	1258	57	macrophages	macrophage	NOUN
fnp-3528	1258	58	.	.	PUNCT
fnp-3528	1259	1	environ	environ	PROPN
fnp-3528	1259	2	pollut	pollut	VERB
fnp-3528	1259	3	2020	2020	NUM
fnp-3528	1259	4	,	,	PUNCT
fnp-3528	1259	5	264	264	NUM
fnp-3528	1259	6	,	,	PUNCT
fnp-3528	1259	7	114723	114723	NUM
fnp-3528	1259	8	.	.	PUNCT
fnp-3528	1260	1	phang	phang	PROPN
fnp-3528	1260	2	,	,	PUNCT
fnp-3528	1260	3	s.	s.	PROPN
fnp-3528	1260	4	w.	w.	PROPN
fnp-3528	1260	5	;	;	PUNCT
fnp-3528	1260	6	ooi	ooi	PROPN
fnp-3528	1260	7	,	,	PUNCT
fnp-3528	1260	8	b.	b.	PROPN
fnp-3528	1260	9	k.	k.	PROPN
fnp-3528	1260	10	;	;	PUNCT
fnp-3528	1260	11	ahemad	ahemad	PROPN
fnp-3528	1260	12	,	,	PUNCT
fnp-3528	1260	13	n.	n.	NOUN
fnp-3528	1260	14	;	;	PUNCT
fnp-3528	1260	15	yap	yap	PROPN
fnp-3528	1260	16	,	,	PUNCT
fnp-3528	1260	17	w.	w.	PROPN
fnp-3528	1260	18	h.	h.	PROPN
fnp-3528	1260	19	maslinic	maslinic	PROPN
fnp-3528	1260	20	acid	acid	NOUN
fnp-3528	1260	21	suppresses	suppress	VERB
fnp-3528	1260	22	macrophage	macrophage	ADJ
fnp-3528	1260	23	foam	foam	NOUN
fnp-3528	1260	24	cells	cell	NOUN
fnp-3528	1260	25	formation	formation	NOUN
fnp-3528	1260	26	:	:	PUNCT
fnp-3528	1260	27	regulation	regulation	NOUN
fnp-3528	1260	28	of	of	ADP
fnp-3528	1260	29	monocyte	monocyte	NOUN
fnp-3528	1260	30	recruitment	recruitment	NOUN
fnp-3528	1260	31	and	and	CCONJ
fnp-3528	1260	32	macrophage	macrophage	ADJ
fnp-3528	1260	33	lipids	lipids	ADJ
fnp-3528	1260	34	homeostasis	homeostasis	NOUN
fnp-3528	1260	35	.	.	PUNCT
fnp-3528	1261	1	vascul	vascul	NOUN
fnp-3528	1261	2	pharmacol	pharmacol	PROPN
fnp-3528	1261	3	2020	2020	NUM
fnp-3528	1261	4	,	,	PUNCT
fnp-3528	1261	5	128	128	NUM
fnp-3528	1261	6	-	-	SYM
fnp-3528	1261	7	129	129	NUM
fnp-3528	1261	8	,	,	PUNCT
fnp-3528	1261	9	106675	106675	NUM
fnp-3528	1261	10	.	.	PUNCT
fnp-3528	1262	1	lou	lou	PROPN
fnp-3528	1262	2	,	,	PUNCT
fnp-3528	1262	3	k.	k.	PROPN
fnp-3528	1262	4	;	;	PUNCT
fnp-3528	1262	5	huang	huang	PROPN
fnp-3528	1262	6	,	,	PUNCT
fnp-3528	1262	7	p.	p.	PROPN
fnp-3528	1262	8	;	;	PUNCT
fnp-3528	1262	9	ma	ma	PROPN
fnp-3528	1262	10	,	,	PUNCT
fnp-3528	1262	11	h.	h.	PROPN
fnp-3528	1262	12	;	;	PUNCT
fnp-3528	1262	13	wang	wang	PROPN
fnp-3528	1262	14	,	,	PUNCT
fnp-3528	1262	15	x.	x.	PROPN
fnp-3528	1262	16	;	;	PUNCT
fnp-3528	1262	17	xu	xu	PROPN
fnp-3528	1262	18	,	,	PUNCT
fnp-3528	1262	19	h.	h.	PROPN
fnp-3528	1262	20	;	;	PUNCT
fnp-3528	1262	21	wang	wang	PROPN
fnp-3528	1262	22	,	,	PUNCT
fnp-3528	1262	23	w.	w.	PROPN
fnp-3528	1262	24	orlistat	orlistat	PROPN
fnp-3528	1262	25	increases	increase	VERB
fnp-3528	1262	26	arsenite	arsenite	ADJ
fnp-3528	1262	27	tolerance	tolerance	NOUN
fnp-3528	1262	28	in	in	ADP
fnp-3528	1262	29	thp-1	thp-1	PUNCT
fnp-3528	1262	30	derived	derive	VERB
fnp-3528	1262	31	macrophages	macrophage	NOUN
fnp-3528	1262	32	through	through	ADP
fnp-3528	1262	33	the	the	DET
fnp-3528	1262	34	up	up	NOUN
fnp-3528	1262	35	-	-	PUNCT
fnp-3528	1262	36	regulation	regulation	NOUN
fnp-3528	1262	37	of	of	ADP
fnp-3528	1262	38	abca1	abca1	NOUN
fnp-3528	1262	39	.	.	PUNCT
fnp-3528	1263	1	drug	drug	NOUN
fnp-3528	1263	2	chem	chem	NOUN
fnp-3528	1263	3	toxicol	toxicol	PROPN
fnp-3528	1263	4	2019	2019	NUM
fnp-3528	1263	5	,	,	PUNCT
fnp-3528	1263	6	1	1	NUM
fnp-3528	1263	7	-	-	SYM
fnp-3528	1263	8	9	9	NUM
fnp-3528	1263	9	.	.	PUNCT
fnp-3528	1264	1	chen	chen	PROPN
fnp-3528	1264	2	,	,	PUNCT
fnp-3528	1264	3	c.	c.	PROPN
fnp-3528	1264	4	h.	h.	PROPN
fnp-3528	1264	5	;	;	PUNCT
fnp-3528	1264	6	zhao	zhao	PROPN
fnp-3528	1264	7	,	,	PUNCT
fnp-3528	1264	8	j.	j.	PROPN
fnp-3528	1264	9	f.	f.	PROPN
fnp-3528	1264	10	;	;	PUNCT
fnp-3528	1264	11	hsu	hsu	PROPN
fnp-3528	1264	12	,	,	PUNCT
fnp-3528	1264	13	c.	c.	PROPN
fnp-3528	1264	14	p.	p.	PROPN
fnp-3528	1264	15	;	;	PUNCT
fnp-3528	1264	16	kou	kou	PROPN
fnp-3528	1264	17	,	,	PUNCT
fnp-3528	1264	18	y.	y.	PROPN
fnp-3528	1264	19	r.	r.	PROPN
fnp-3528	1264	20	;	;	PUNCT
fnp-3528	1264	21	lu	lu	PROPN
fnp-3528	1264	22	,	,	PUNCT
fnp-3528	1264	23	t.	t.	NOUN
fnp-3528	1264	24	m.	m.	NOUN
fnp-3528	1264	25	;	;	PUNCT
fnp-3528	1264	26	lee	lee	PROPN
fnp-3528	1264	27	,	,	PUNCT
fnp-3528	1264	28	t.	t.	PROPN
fnp-3528	1264	29	s.	s.	PROPN
fnp-3528	1265	1	the	the	DET
fnp-3528	1265	2	detrimental	detrimental	ADJ
fnp-3528	1265	3	effect	effect	NOUN
fnp-3528	1265	4	of	of	ADP
fnp-3528	1265	5	asymmetric	asymmetric	ADJ
fnp-3528	1265	6	dimethylarginine	dimethylarginine	NOUN
fnp-3528	1265	7	on	on	ADP
fnp-3528	1265	8	cholesterol	cholesterol	NOUN
fnp-3528	1265	9	efflux	efflux	NOUN
fnp-3528	1265	10	of	of	ADP
fnp-3528	1265	11	macrophage	macrophage	ADJ
fnp-3528	1265	12	foam	foam	NOUN
fnp-3528	1265	13	cells	cell	NOUN
fnp-3528	1265	14	:	:	PUNCT
fnp-3528	1265	15	role	role	NOUN
fnp-3528	1265	16	of	of	ADP
fnp-3528	1265	17	the	the	DET
fnp-3528	1265	18	nox	nox	PROPN
fnp-3528	1265	19	/	/	SYM
fnp-3528	1265	20	ros	ros	PROPN
fnp-3528	1265	21	signaling	signaling	NOUN
fnp-3528	1265	22	.	.	PUNCT
fnp-3528	1266	1	free	free	ADJ
fnp-3528	1266	2	radic	radic	ADJ
fnp-3528	1266	3	biol	biol	PROPN
fnp-3528	1266	4	med	me	VERB
fnp-3528	1266	5	2019	2019	NUM
fnp-3528	1266	6	,	,	PUNCT
fnp-3528	1266	7	143	143	NUM
fnp-3528	1266	8	,	,	PUNCT
fnp-3528	1266	9	354	354	NUM
fnp-3528	1266	10	-	-	SYM
fnp-3528	1266	11	65	65	NUM
fnp-3528	1266	12	.	.	PUNCT
fnp-3528	1267	1	zhao	zhao	PROPN
fnp-3528	1267	2	,	,	PUNCT
fnp-3528	1267	3	w.	w.	PROPN
fnp-3528	1267	4	;	;	PUNCT
fnp-3528	1267	5	wang	wang	PROPN
fnp-3528	1267	6	,	,	PUNCT
fnp-3528	1267	7	l.	l.	PROPN
fnp-3528	1267	8	;	;	PUNCT
fnp-3528	1267	9	haller	haller	PROPN
fnp-3528	1267	10	,	,	PUNCT
fnp-3528	1267	11	v.	v.	PROPN
fnp-3528	1267	12	;	;	PUNCT
fnp-3528	1267	13	ritsch	ritsch	PROPN
fnp-3528	1267	14	,	,	PUNCT
fnp-3528	1267	15	a.	a.	NOUN
fnp-3528	1267	16	a	a	DET
fnp-3528	1267	17	novel	novel	ADJ
fnp-3528	1267	18	candidate	candidate	NOUN
fnp-3528	1267	19	for	for	ADP
fnp-3528	1267	20	prevention	prevention	NOUN
fnp-3528	1267	21	and	and	CCONJ
fnp-3528	1267	22	treatment	treatment	NOUN
fnp-3528	1267	23	of	of	ADP
fnp-3528	1267	24	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1267	25	:	:	PUNCT
fnp-3528	1267	26	urolithin	urolithin	PROPN
fnp-3528	1267	27	b	b	PROPN
fnp-3528	1267	28	decreases	decrease	VERB
fnp-3528	1267	29	lipid	lipid	NOUN
fnp-3528	1267	30	plaque	plaque	NOUN
fnp-3528	1267	31	deposition	deposition	NOUN
fnp-3528	1267	32	in	in	ADP
fnp-3528	1267	33	apoe(-/-	apoe(-/-	NUM
fnp-3528	1267	34	)	)	PUNCT
fnp-3528	1267	35	mice	mouse	NOUN
fnp-3528	1267	36	and	and	CCONJ
fnp-3528	1267	37	increases	increase	VERB
fnp-3528	1267	38	early	early	ADJ
fnp-3528	1267	39	stages	stage	NOUN
fnp-3528	1267	40	of	of	ADP
fnp-3528	1267	41	reverse	reverse	ADJ
fnp-3528	1267	42	cholesterol	cholesterol	NOUN
fnp-3528	1267	43	transport	transport	NOUN
fnp-3528	1267	44	in	in	ADP
fnp-3528	1267	45	ox	ox	ADJ
fnp-3528	1267	46	-	-	ADJ
fnp-3528	1267	47	ldl	ldl	NOUN
fnp-3528	1267	48	treated	treat	VERB
fnp-3528	1267	49	macrophages	macrophage	NOUN
fnp-3528	1267	50	cells	cell	NOUN
fnp-3528	1267	51	.	.	PUNCT
fnp-3528	1268	1	mol	mol	ADP
fnp-3528	1268	2	nutr	nutr	NOUN
fnp-3528	1268	3	food	food	NOUN
fnp-3528	1268	4	res	re	NOUN
fnp-3528	1268	5	2019	2019	NUM
fnp-3528	1268	6	,	,	PUNCT
fnp-3528	1268	7	63	63	NUM
fnp-3528	1268	8	,	,	PUNCT
fnp-3528	1268	9	e1800887	e1800887	PROPN
fnp-3528	1268	10	.	.	PUNCT
fnp-3528	1269	1	zhong	zhong	PROPN
fnp-3528	1269	2	,	,	PUNCT
fnp-3528	1269	3	y.	y.	PROPN
fnp-3528	1269	4	;	;	PUNCT
fnp-3528	1269	5	feng	feng	PROPN
fnp-3528	1269	6	,	,	PUNCT
fnp-3528	1269	7	j.	j.	PROPN
fnp-3528	1269	8	;	;	PUNCT
fnp-3528	1269	9	fan	fan	PROPN
fnp-3528	1269	10	,	,	PUNCT
fnp-3528	1269	11	z.	z.	PROPN
fnp-3528	1269	12	;	;	PUNCT
fnp-3528	1269	13	li	li	PROPN
fnp-3528	1269	14	,	,	PUNCT
fnp-3528	1269	15	j.	j.	PROPN
fnp-3528	1269	16	curcumin	curcumin	PROPN
fnp-3528	1269	17	increases	increase	VERB
fnp-3528	1269	18	cholesterol	cholesterol	NOUN
fnp-3528	1269	19	efflux	efflux	VERB
fnp-3528	1269	20	via	via	ADP
fnp-3528	1269	21	heme	heme	NOUN
fnp-3528	1269	22	oxygenase1mediated	oxygenase1mediate	VERB
fnp-3528	1269	23	abca1	abca1	NOUN
fnp-3528	1269	24	and	and	CCONJ
fnp-3528	1269	25	srbi	srbi	PROPN
fnp-3528	1269	26	expression	expression	NOUN
fnp-3528	1269	27	in	in	ADP
fnp-3528	1269	28	macrophages	macrophage	NOUN
fnp-3528	1269	29	.	.	PUNCT
fnp-3528	1270	1	mol	mol	ADP
fnp-3528	1270	2	med	med	PROPN
fnp-3528	1270	3	rep	rep	PROPN
fnp-3528	1270	4	2018	2018	NUM
fnp-3528	1270	5	,	,	PUNCT
fnp-3528	1270	6	17	17	NUM
fnp-3528	1270	7	,	,	PUNCT
fnp-3528	1270	8	6138	6138	NUM
fnp-3528	1270	9	-	-	SYM
fnp-3528	1270	10	43	43	NUM
fnp-3528	1270	11	.	.	PUNCT
fnp-3528	1271	1	wang	wang	PROPN
fnp-3528	1271	2	,	,	PUNCT
fnp-3528	1271	3	l.	l.	PROPN
fnp-3528	1271	4	;	;	PUNCT
fnp-3528	1271	5	wesemann	wesemann	PROPN
fnp-3528	1271	6	,	,	PUNCT
fnp-3528	1271	7	s.	s.	PROPN
fnp-3528	1271	8	;	;	PUNCT
fnp-3528	1271	9	krenn	krenn	PROPN
fnp-3528	1271	10	,	,	PUNCT
fnp-3528	1271	11	l.	l.	PROPN
fnp-3528	1271	12	;	;	PUNCT
fnp-3528	1271	13	ladurner	ladurner	ADJ
fnp-3528	1271	14	,	,	PUNCT
fnp-3528	1271	15	a.	a.	NOUN
fnp-3528	1271	16	;	;	PUNCT
fnp-3528	1271	17	heiss	heiss	PROPN
fnp-3528	1271	18	,	,	PUNCT
fnp-3528	1271	19	e.	e.	PROPN
fnp-3528	1271	20	h.	h.	PROPN
fnp-3528	1271	21	;	;	PUNCT
fnp-3528	1271	22	dirsch	dirsch	PROPN
fnp-3528	1271	23	,	,	PUNCT
fnp-3528	1271	24	v.	v.	ADP
fnp-3528	1271	25	m.	m.	NOUN
fnp-3528	1271	26	;	;	PUNCT
fnp-3528	1271	27	atanasov	atanasov	NOUN
fnp-3528	1271	28	,	,	PUNCT
fnp-3528	1271	29	a.	a.	PROPN
fnp-3528	1271	30	g.	g.	PROPN
fnp-3528	1271	31	erythrodiol	erythrodiol	PROPN
fnp-3528	1271	32	,	,	PUNCT
fnp-3528	1271	33	an	an	DET
fnp-3528	1271	34	olive	olive	ADJ
fnp-3528	1271	35	oil	oil	NOUN
fnp-3528	1271	36	constituent	constituent	NOUN
fnp-3528	1271	37	,	,	PUNCT
fnp-3528	1271	38	increases	increase	VERB
fnp-3528	1271	39	the	the	DET
fnp-3528	1271	40	half	half	ADJ
fnp-3528	1271	41	-	-	PUNCT
fnp-3528	1271	42	life	life	NOUN
fnp-3528	1271	43	of	of	ADP
fnp-3528	1271	44	abca1	abca1	NOUN
fnp-3528	1271	45	and	and	CCONJ
fnp-3528	1271	46	enhances	enhance	VERB
fnp-3528	1271	47	cholesterol	cholesterol	NOUN
fnp-3528	1271	48	efflux	efflux	NOUN
fnp-3528	1271	49	from	from	ADP
fnp-3528	1271	50	thp-1	thp-1	ADV
fnp-3528	1271	51	-	-	PUNCT
fnp-3528	1271	52	derived	derive	VERB
fnp-3528	1271	53	macrophages	macrophage	NOUN
fnp-3528	1271	54	.	.	PUNCT
fnp-3528	1272	1	front	front	ADJ
fnp-3528	1272	2	pharmacol	pharmacol	PROPN
fnp-3528	1272	3	2017	2017	NUM
fnp-3528	1272	4	,	,	PUNCT
fnp-3528	1272	5	8	8	NUM
fnp-3528	1272	6	,	,	PUNCT
fnp-3528	1272	7	375	375	NUM
fnp-3528	1272	8	.	.	PUNCT
fnp-3528	1272	9	kemmerer	kemmerer	NOUN
fnp-3528	1272	10	,	,	PUNCT
fnp-3528	1272	11	m.	m.	NOUN
fnp-3528	1272	12	;	;	PUNCT
fnp-3528	1272	13	wittig	wittig	X
fnp-3528	1272	14	,	,	PUNCT
fnp-3528	1272	15	i.	i.	NOUN
fnp-3528	1272	16	;	;	PUNCT
fnp-3528	1272	17	richter	richter	PROPN
fnp-3528	1272	18	,	,	PUNCT
fnp-3528	1272	19	f.	f.	PROPN
fnp-3528	1272	20	;	;	PUNCT
fnp-3528	1272	21	brune	brune	PROPN
fnp-3528	1272	22	,	,	PUNCT
fnp-3528	1272	23	b.	b.	PROPN
fnp-3528	1272	24	;	;	PUNCT
fnp-3528	1272	25	namgaladze	namgaladze	ADJ
fnp-3528	1272	26	,	,	PUNCT
fnp-3528	1272	27	d.	d.	PROPN
fnp-3528	1272	28	ampk	ampk	PROPN
fnp-3528	1272	29	activates	activate	VERB
fnp-3528	1272	30	lxralpha	lxralpha	NOUN
fnp-3528	1272	31	and	and	CCONJ
fnp-3528	1272	32	abca1	abca1	NOUN
fnp-3528	1272	33	expression	expression	NOUN
fnp-3528	1272	34	in	in	ADP
fnp-3528	1272	35	human	human	ADJ
fnp-3528	1272	36	macrophages	macrophage	NOUN
fnp-3528	1272	37	.	.	PUNCT
fnp-3528	1273	1	int	int	PROPN
fnp-3528	1273	2	j	j	PROPN
fnp-3528	1273	3	biochem	biochem	PROPN
fnp-3528	1273	4	cell	cell	NOUN
fnp-3528	1273	5	biol	biol	PROPN
fnp-3528	1273	6	2016	2016	NUM
fnp-3528	1273	7	,	,	PUNCT
fnp-3528	1273	8	78	78	NUM
fnp-3528	1273	9	,	,	PUNCT
fnp-3528	1273	10	1	1	NUM
fnp-3528	1273	11	-	-	SYM
fnp-3528	1273	12	9	9	NUM
fnp-3528	1273	13	.	.	PUNCT
fnp-3528	1274	1	li	li	PROPN
fnp-3528	1274	2	,	,	PUNCT
fnp-3528	1274	3	x.	x.	PROPN
fnp-3528	1274	4	y.	y.	PROPN
fnp-3528	1274	5	;	;	PUNCT
fnp-3528	1274	6	kong	kong	PROPN
fnp-3528	1274	7	,	,	PUNCT
fnp-3528	1274	8	l.	l.	PROPN
fnp-3528	1274	9	x.	x.	PROPN
fnp-3528	1274	10	;	;	PUNCT
fnp-3528	1274	11	li	li	PROPN
fnp-3528	1274	12	,	,	PUNCT
fnp-3528	1274	13	j.	j.	PROPN
fnp-3528	1274	14	;	;	PUNCT
fnp-3528	1274	15	he	he	PRON
fnp-3528	1274	16	,	,	PUNCT
fnp-3528	1274	17	h.	h.	PROPN
fnp-3528	1274	18	x.	x.	PROPN
fnp-3528	1274	19	;	;	PUNCT
fnp-3528	1274	20	zhou	zhou	PROPN
fnp-3528	1274	21	,	,	PUNCT
fnp-3528	1274	22	y.	y.	PROPN
fnp-3528	1274	23	d.	d.	PROPN
fnp-3528	1274	24	kaempferol	kaempferol	PROPN
fnp-3528	1274	25	suppresses	suppress	VERB
fnp-3528	1274	26	lipid	lipid	ADJ
fnp-3528	1274	27	accumulation	accumulation	NOUN
fnp-3528	1274	28	in	in	ADP
fnp-3528	1274	29	macrophages	macrophage	NOUN
fnp-3528	1274	30	through	through	ADP
fnp-3528	1274	31	the	the	DET
fnp-3528	1274	32	downregulation	downregulation	NOUN
fnp-3528	1274	33	of	of	ADP
fnp-3528	1274	34	cluster	cluster	NOUN
fnp-3528	1274	35	of	of	ADP
fnp-3528	1274	36	differentiation	differentiation	NOUN
fnp-3528	1274	37	36	36	NUM
fnp-3528	1274	38	and	and	CCONJ
fnp-3528	1274	39	the	the	DET
fnp-3528	1274	40	upregulation	upregulation	NOUN
fnp-3528	1274	41	of	of	ADP
fnp-3528	1274	42	scavenger	scavenger	NOUN
fnp-3528	1274	43	receptor	receptor	NOUN
fnp-3528	1274	44	class	class	NOUN
fnp-3528	1274	45	b	b	PROPN
fnp-3528	1274	46	type	type	NOUN
fnp-3528	1274	47	i	i	PROPN
fnp-3528	1274	48	and	and	CCONJ
fnp-3528	1274	49	atp	atp	NOUN
fnp-3528	1274	50	-	-	PUNCT
fnp-3528	1274	51	binding	bind	VERB
fnp-3528	1274	52	cassette	cassette	NOUN
fnp-3528	1274	53	transporters	transporter	NOUN
fnp-3528	1274	54	a1	a1	NOUN
fnp-3528	1274	55	and	and	CCONJ
fnp-3528	1274	56	g1	g1	NOUN
fnp-3528	1274	57	.	.	PUNCT
fnp-3528	1275	1	int	int	PROPN
fnp-3528	1275	2	j	j	PROPN
fnp-3528	1275	3	mol	mol	ADP
fnp-3528	1275	4	med	med	PROPN
fnp-3528	1275	5	2013	2013	NUM
fnp-3528	1275	6	,	,	PUNCT
fnp-3528	1275	7	31	31	NUM
fnp-3528	1275	8	,	,	PUNCT
fnp-3528	1275	9	331	331	NUM
fnp-3528	1275	10	-	-	SYM
fnp-3528	1275	11	8	8	NUM
fnp-3528	1275	12	.	.	PUNCT
fnp-3528	1276	1	seneviratne	seneviratne	NOUN
fnp-3528	1276	2	,	,	PUNCT
fnp-3528	1276	3	a.	a.	NOUN
fnp-3528	1276	4	;	;	PUNCT
fnp-3528	1276	5	cave	cave	PROPN
fnp-3528	1276	6	,	,	PUNCT
fnp-3528	1276	7	l.	l.	PROPN
fnp-3528	1276	8	;	;	PUNCT
fnp-3528	1276	9	hyde	hyde	PROPN
fnp-3528	1276	10	,	,	PUNCT
fnp-3528	1276	11	g.	g.	PROPN
fnp-3528	1276	12	;	;	PUNCT
fnp-3528	1276	13	moestrup	moestrup	NOUN
fnp-3528	1276	14	,	,	PUNCT
fnp-3528	1276	15	s.	s.	PROPN
fnp-3528	1276	16	k.	k.	PROPN
fnp-3528	1276	17	;	;	PUNCT
fnp-3528	1276	18	carling	carling	PROPN
fnp-3528	1276	19	,	,	PUNCT
fnp-3528	1276	20	d.	d.	PROPN
fnp-3528	1276	21	;	;	PUNCT
fnp-3528	1276	22	mason	mason	PROPN
fnp-3528	1276	23	,	,	PUNCT
fnp-3528	1276	24	j.	j.	PROPN
fnp-3528	1276	25	c.	c.	PROPN
fnp-3528	1276	26	;	;	PUNCT
fnp-3528	1276	27	haskard	haskard	PROPN
fnp-3528	1276	28	,	,	PUNCT
fnp-3528	1276	29	d.	d.	PROPN
fnp-3528	1276	30	o.	o.	PROPN
fnp-3528	1276	31	;	;	PUNCT
fnp-3528	1276	32	boyle	boyle	PROPN
fnp-3528	1276	33	,	,	PUNCT
fnp-3528	1276	34	j.	j.	PROPN
fnp-3528	1276	35	j.	j.	PROPN
fnp-3528	1276	36	metformin	metformin	PROPN
fnp-3528	1276	37	directly	directly	ADV
fnp-3528	1276	38	suppresses	suppress	VERB
fnp-3528	1276	39	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1276	40	in	in	ADP
fnp-3528	1276	41	normoglycaemic	normoglycaemic	ADJ
fnp-3528	1276	42	mice	mouse	NOUN
fnp-3528	1276	43	via	via	ADP
fnp-3528	1276	44	haematopoietic	haematopoietic	ADJ
fnp-3528	1276	45	adenosine	adenosine	NOUN
fnp-3528	1276	46	monophosphate	monophosphate	NOUN
fnp-3528	1276	47	-	-	PUNCT
fnp-3528	1276	48	activated	activate	VERB
fnp-3528	1276	49	protein	protein	NOUN
fnp-3528	1276	50	kinase	kinase	NOUN
fnp-3528	1276	51	.	.	PUNCT
fnp-3528	1277	1	cardiovasc	cardiovasc	PROPN
fnp-3528	1277	2	res	re	VERB
fnp-3528	1277	3	2021	2021	NUM
fnp-3528	1277	4	,	,	PUNCT
fnp-3528	1277	5	117	117	NUM
fnp-3528	1277	6	,	,	PUNCT
fnp-3528	1277	7	1295	1295	NUM
fnp-3528	1277	8	-	-	SYM
fnp-3528	1277	9	308	308	NUM
fnp-3528	1277	10	.	.	PUNCT
fnp-3528	1278	1	lu	lu	PROPN
fnp-3528	1278	2	,	,	PUNCT
fnp-3528	1278	3	s.	s.	PROPN
fnp-3528	1278	4	;	;	PUNCT
fnp-3528	1278	5	luo	luo	PROPN
fnp-3528	1278	6	,	,	PUNCT
fnp-3528	1278	7	y.	y.	PROPN
fnp-3528	1278	8	;	;	PUNCT
fnp-3528	1278	9	sun	sun	PROPN
fnp-3528	1278	10	,	,	PUNCT
fnp-3528	1278	11	g.	g.	PROPN
fnp-3528	1278	12	;	;	PUNCT
fnp-3528	1278	13	sun	sun	NOUN
fnp-3528	1278	14	,	,	PUNCT
fnp-3528	1278	15	x.	x.	NOUN
fnp-3528	1278	16	ginsenoside	ginsenoside	PROPN
fnp-3528	1278	17	compound	compound	PROPN
fnp-3528	1278	18	k	k	PROPN
fnp-3528	1278	19	attenuates	attenuate	VERB
fnp-3528	1278	20	ox	ox	ADJ
fnp-3528	1278	21	-	-	ADJ
fnp-3528	1278	22	ldl	ldl	ADJ
fnp-3528	1278	23	-	-	PUNCT
fnp-3528	1278	24	mediated	mediate	VERB
fnp-3528	1278	25	macrophage	macrophage	ADJ
fnp-3528	1278	26	inflammation	inflammation	NOUN
fnp-3528	1278	27	and	and	CCONJ
fnp-3528	1278	28	foam	foam	NOUN
fnp-3528	1278	29	cell	cell	NOUN
fnp-3528	1278	30	formation	formation	NOUN
fnp-3528	1278	31	via	via	ADP
fnp-3528	1278	32	autophagy	autophagy	ADJ
fnp-3528	1278	33	induction	induction	NOUN
fnp-3528	1278	34	and	and	CCONJ
fnp-3528	1278	35	modulating	modulate	VERB
fnp-3528	1278	36	nf	nf	NOUN
fnp-3528	1278	37	-	-	PUNCT
fnp-3528	1278	38	kappab	kappab	NOUN
fnp-3528	1278	39	,	,	PUNCT
fnp-3528	1278	40	p38	p38	NOUN
fnp-3528	1278	41	,	,	PUNCT
fnp-3528	1278	42	and	and	CCONJ
fnp-3528	1278	43	jnk	jnk	PROPN
fnp-3528	1278	44	mapk	mapk	PROPN
fnp-3528	1278	45	signaling	signal	VERB
fnp-3528	1278	46	.	.	PUNCT
fnp-3528	1279	1	front	front	ADJ
fnp-3528	1279	2	pharmacol	pharmacol	PROPN
fnp-3528	1279	3	2020	2020	NUM
fnp-3528	1279	4	,	,	PUNCT
fnp-3528	1279	5	11	11	NUM
fnp-3528	1279	6	,	,	PUNCT
fnp-3528	1279	7	567238	567238	NUM
fnp-3528	1279	8	.	.	PUNCT
fnp-3528	1280	1	wang	wang	PROPN
fnp-3528	1280	2	,	,	PUNCT
fnp-3528	1280	3	m.	m.	PROPN
fnp-3528	1280	4	s.	s.	PROPN
fnp-3528	1280	5	;	;	PUNCT
fnp-3528	1280	6	han	han	PROPN
fnp-3528	1280	7	,	,	PUNCT
fnp-3528	1280	8	q.	q.	PROPN
fnp-3528	1280	9	s.	s.	PROPN
fnp-3528	1280	10	;	;	PUNCT
fnp-3528	1280	11	jia	jia	PROPN
fnp-3528	1280	12	,	,	PUNCT
fnp-3528	1280	13	z.	z.	PROPN
fnp-3528	1280	14	r.	r.	PROPN
fnp-3528	1280	15	;	;	PUNCT
fnp-3528	1280	16	chen	chen	PROPN
fnp-3528	1280	17	,	,	PUNCT
fnp-3528	1280	18	c.	c.	PROPN
fnp-3528	1280	19	s.	s.	PROPN
fnp-3528	1280	20	;	;	PUNCT
fnp-3528	1280	21	qiao	qiao	PROPN
fnp-3528	1280	22	,	,	PUNCT
fnp-3528	1280	23	c.	c.	PROPN
fnp-3528	1280	24	;	;	PUNCT
fnp-3528	1280	25	liu	liu	PROPN
fnp-3528	1280	26	,	,	PUNCT
fnp-3528	1280	27	q.	q.	PROPN
fnp-3528	1280	28	q.	q.	PROPN
fnp-3528	1280	29	;	;	PUNCT
fnp-3528	1280	30	zhang	zhang	PROPN
fnp-3528	1280	31	,	,	PUNCT
fnp-3528	1280	32	y.	y.	PROPN
fnp-3528	1280	33	m.	m.	PROPN
fnp-3528	1280	34	;	;	PUNCT
fnp-3528	1280	35	wang	wang	PROPN
fnp-3528	1280	36	,	,	PUNCT
fnp-3528	1280	37	k.	k.	PROPN
fnp-3528	1280	38	w.	w.	PROPN
fnp-3528	1280	39	;	;	PUNCT
fnp-3528	1280	40	wang	wang	PROPN
fnp-3528	1280	41	,	,	PUNCT
fnp-3528	1280	42	j.	j.	PROPN
fnp-3528	1280	43	;	;	PUNCT
fnp-3528	1280	44	xiao	xiao	PROPN
fnp-3528	1280	45	,	,	PUNCT
fnp-3528	1280	46	k.	k.	PROPN
fnp-3528	1280	47	;	;	PUNCT
fnp-3528	1280	48	ding	ding	PROPN
fnp-3528	1280	49	,	,	PUNCT
fnp-3528	1280	50	x.	x.	PROPN
fnp-3528	1280	51	s.	s.	PROPN
fnp-3528	1280	52	pparalpha	pparalpha	PROPN
fnp-3528	1280	53	agonist	agonist	PROPN
fnp-3528	1280	54	fenofibrate	fenofibrate	NOUN
fnp-3528	1280	55	relieves	relieve	VERB
fnp-3528	1280	56	acquired	acquire	VERB
fnp-3528	1280	57	resistance	resistance	NOUN
fnp-3528	1280	58	to	to	ADP
fnp-3528	1280	59	gefitinib	gefitinib	NOUN
fnp-3528	1280	60	in	in	ADP
fnp-3528	1280	61	non	non	ADJ
fnp-3528	1280	62	-	-	ADJ
fnp-3528	1280	63	small	small	ADJ
fnp-3528	1280	64	cell	cell	NOUN
fnp-3528	1280	65	lung	lung	NOUN
fnp-3528	1280	66	cancer	cancer	NOUN
fnp-3528	1280	67	by	by	ADP
fnp-3528	1280	68	promoting	promote	VERB
fnp-3528	1280	69	apoptosis	apoptosis	NOUN
fnp-3528	1280	70	via	via	ADP
fnp-3528	1280	71	pparalpha	pparalpha	PROPN
fnp-3528	1280	72	/	/	SYM
fnp-3528	1280	73	ampk	ampk	PROPN
fnp-3528	1280	74	/	/	SYM
fnp-3528	1280	75	akt	akt	PROPN
fnp-3528	1280	76	/	/	SYM
fnp-3528	1280	77	foxo1	foxo1	PROPN
fnp-3528	1280	78	pathway	pathway	NOUN
fnp-3528	1280	79	.	.	PUNCT
fnp-3528	1281	1	acta	acta	PROPN
fnp-3528	1281	2	pharmacol	pharmacol	PROPN
fnp-3528	1281	3	sin	sin	NOUN
fnp-3528	1281	4	2021	2021	NUM
fnp-3528	1281	5	.	.	PUNCT
fnp-3528	1282	1	lundasen	lundasen	VERB
fnp-3528	1282	2	,	,	PUNCT
fnp-3528	1282	3	t.	t.	PROPN
fnp-3528	1282	4	;	;	PUNCT
fnp-3528	1282	5	pedrelli	pedrelli	ADJ
fnp-3528	1282	6	,	,	PUNCT
fnp-3528	1282	7	m.	m.	NOUN
fnp-3528	1282	8	;	;	PUNCT
fnp-3528	1282	9	bjorndal	bjorndal	NOUN
fnp-3528	1282	10	,	,	PUNCT
fnp-3528	1282	11	b.	b.	PROPN
fnp-3528	1282	12	;	;	PUNCT
fnp-3528	1282	13	rozell	rozell	PROPN
fnp-3528	1282	14	,	,	PUNCT
fnp-3528	1282	15	b.	b.	PROPN
fnp-3528	1282	16	;	;	PUNCT
fnp-3528	1282	17	kuiper	kuiper	PROPN
fnp-3528	1282	18	,	,	PUNCT
fnp-3528	1282	19	r.	r.	PROPN
fnp-3528	1282	20	v.	v.	PROPN
fnp-3528	1282	21	;	;	PUNCT
fnp-3528	1282	22	burri	burri	NOUN
fnp-3528	1282	23	,	,	PUNCT
fnp-3528	1282	24	l.	l.	PROPN
fnp-3528	1282	25	;	;	PUNCT
fnp-3528	1282	26	pavanello	pavanello	PROPN
fnp-3528	1282	27	,	,	PUNCT
fnp-3528	1282	28	c.	c.	PROPN
fnp-3528	1282	29	;	;	PUNCT
fnp-3528	1282	30	turri	turri	NOUN
fnp-3528	1282	31	,	,	PUNCT
fnp-3528	1282	32	m.	m.	NOUN
fnp-3528	1282	33	;	;	PUNCT
fnp-3528	1282	34	skorve	skorve	PROPN
fnp-3528	1282	35	,	,	PUNCT
fnp-3528	1282	36	j.	j.	PROPN
fnp-3528	1282	37	;	;	PUNCT
fnp-3528	1282	38	berge	berge	PROPN
fnp-3528	1282	39	,	,	PUNCT
fnp-3528	1282	40	r.	r.	PROPN
fnp-3528	1282	41	k.	k.	PROPN
fnp-3528	1282	42	;	;	PUNCT
fnp-3528	1282	43	alexson	alexson	PROPN
fnp-3528	1282	44	,	,	PUNCT
fnp-3528	1282	45	s.	s.	PROPN
fnp-3528	1282	46	e.	e.	PROPN
fnp-3528	1282	47	h.	h.	PROPN
fnp-3528	1282	48	;	;	PUNCT
fnp-3528	1282	49	tillander	tillander	NOUN
fnp-3528	1282	50	,	,	PUNCT
fnp-3528	1282	51	v.	v.	ADP
fnp-3528	1282	52	the	the	DET
fnp-3528	1282	53	ppar	ppar	NOUN
fnp-3528	1282	54	pan	pan	ADJ
fnp-3528	1282	55	-	-	ADJ
fnp-3528	1282	56	agonist	agonist	ADJ
fnp-3528	1282	57	tetradecylthioacetic	tetradecylthioacetic	ADJ
fnp-3528	1282	58	acid	acid	NOUN
fnp-3528	1282	59	promotes	promote	VERB
fnp-3528	1282	60	redistribution	redistribution	NOUN
fnp-3528	1282	61	of	of	ADP
fnp-3528	1282	62	plasma	plasma	NOUN
fnp-3528	1282	63	cholesterol	cholesterol	NOUN
fnp-3528	1282	64	towards	towards	ADP
fnp-3528	1282	65	large	large	ADJ
fnp-3528	1282	66	hdl	hdl	PROPN
fnp-3528	1282	67	.	.	PUNCT
fnp-3528	1283	1	plos	plos	PROPN
fnp-3528	1283	2	one	one	NUM
fnp-3528	1283	3	2020	2020	NUM
fnp-3528	1283	4	,	,	PUNCT
fnp-3528	1283	5	15	15	NUM
fnp-3528	1283	6	,	,	PUNCT
fnp-3528	1283	7	e0229322	e0229322	PROPN
fnp-3528	1283	8	.	.	PROPN
fnp-3528	1283	9	shen	shen	PROPN
fnp-3528	1283	10	,	,	PUNCT
fnp-3528	1283	11	c.	c.	PROPN
fnp-3528	1283	12	y.	y.	PROPN
fnp-3528	1283	13	;	;	PUNCT
fnp-3528	1283	14	lin	lin	PROPN
fnp-3528	1283	15	,	,	PUNCT
fnp-3528	1283	16	j.	j.	PROPN
fnp-3528	1283	17	j.	j.	PROPN
fnp-3528	1283	18	;	;	PUNCT
fnp-3528	1283	19	jiang	jiang	PROPN
fnp-3528	1283	20	,	,	PUNCT
fnp-3528	1283	21	j.	j.	PROPN
fnp-3528	1283	22	g.	g.	PROPN
fnp-3528	1283	23	;	;	PUNCT
fnp-3528	1283	24	wang	wang	PROPN
fnp-3528	1283	25	,	,	PUNCT
fnp-3528	1283	26	t.	t.	PROPN
fnp-3528	1283	27	x.	x.	PROPN
fnp-3528	1283	28	;	;	PUNCT
fnp-3528	1283	29	zhu	zhu	PROPN
fnp-3528	1283	30	,	,	PUNCT
fnp-3528	1283	31	w.	w.	PROPN
fnp-3528	1283	32	potential	potential	ADJ
fnp-3528	1283	33	roles	role	NOUN
fnp-3528	1283	34	of	of	ADP
fnp-3528	1283	35	dietary	dietary	ADJ
fnp-3528	1283	36	flavonoids	flavonoid	NOUN
fnp-3528	1283	37	from	from	ADP
fnp-3528	1283	38	citrus	citrus	PROPN
fnp-3528	1283	39	aurantium	aurantium	PROPN
fnp-3528	1283	40	l.	l.	PROPN
fnp-3528	1283	41	var	var	PROPN
fnp-3528	1283	42	.	.	PUNCT
fnp-3528	1284	1	amara	amara	PROPN
fnp-3528	1284	2	engl	engl	PROPN
fnp-3528	1284	3	.	.	PUNCT
fnp-3528	1285	1	in	in	ADP
fnp-3528	1285	2	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1285	3	development	development	NOUN
fnp-3528	1285	4	.	.	PUNCT
fnp-3528	1286	1	food	food	NOUN
fnp-3528	1286	2	funct	funct	PROPN
fnp-3528	1286	3	2020	2020	NUM
fnp-3528	1286	4	,	,	PUNCT
fnp-3528	1286	5	11	11	NUM
fnp-3528	1286	6	,	,	PUNCT
fnp-3528	1286	7	561	561	NUM
fnp-3528	1286	8	-	-	SYM
fnp-3528	1286	9	71	71	NUM
fnp-3528	1286	10	.	.	PUNCT
fnp-3528	1287	1	lin	lin	PROPN
fnp-3528	1287	2	,	,	PUNCT
fnp-3528	1287	3	y.	y.	PROPN
fnp-3528	1287	4	;	;	PUNCT
fnp-3528	1287	5	ren	ren	PROPN
fnp-3528	1287	6	,	,	PUNCT
fnp-3528	1287	7	n.	n.	PROPN
fnp-3528	1287	8	;	;	PUNCT
fnp-3528	1287	9	li	li	PROPN
fnp-3528	1287	10	,	,	PUNCT
fnp-3528	1287	11	s.	s.	PROPN
fnp-3528	1287	12	;	;	PUNCT
fnp-3528	1287	13	chen	chen	PROPN
fnp-3528	1287	14	,	,	PUNCT
fnp-3528	1287	15	m.	m.	NOUN
fnp-3528	1287	16	;	;	PUNCT
fnp-3528	1287	17	pu	pu	PROPN
fnp-3528	1287	18	,	,	PUNCT
fnp-3528	1287	19	p.	p.	NOUN
fnp-3528	1287	20	novel	novel	ADJ
fnp-3528	1287	21	anti	anti	ADJ
fnp-3528	1287	22	-	-	ADJ
fnp-3528	1287	23	obesity	obesity	ADJ
fnp-3528	1287	24	effect	effect	NOUN
fnp-3528	1287	25	of	of	ADP
fnp-3528	1287	26	scutellarein	scutellarein	NOUN
fnp-3528	1287	27	and	and	CCONJ
fnp-3528	1287	28	potential	potential	ADJ
fnp-3528	1287	29	underlying	underlying	ADJ
fnp-3528	1287	30	mechanism	mechanism	NOUN
fnp-3528	1287	31	of	of	ADP
fnp-3528	1287	32	actions	action	NOUN
fnp-3528	1287	33	.	.	PUNCT
fnp-3528	1287	34	biomed	biome	VERB
fnp-3528	1287	35	pharmacother	pharmacother	ADJ
fnp-3528	1287	36	2019	2019	NUM
fnp-3528	1287	37	,	,	PUNCT
fnp-3528	1287	38	117	117	NUM
fnp-3528	1287	39	,	,	PUNCT
fnp-3528	1287	40	109042	109042	NUM
fnp-3528	1287	41	.	.	PUNCT
fnp-3528	1288	1	guo	guo	PROPN
fnp-3528	1288	2	,	,	PUNCT
fnp-3528	1288	3	t.	t.	PROPN
fnp-3528	1288	4	;	;	PUNCT
fnp-3528	1288	5	liu	liu	PROPN
fnp-3528	1288	6	,	,	PUNCT
fnp-3528	1288	7	q.	q.	PROPN
fnp-3528	1288	8	;	;	PUNCT
fnp-3528	1288	9	hou	hou	PROPN
fnp-3528	1288	10	,	,	PUNCT
fnp-3528	1288	11	p.	p.	PROPN
fnp-3528	1288	12	;	;	PUNCT
fnp-3528	1288	13	li	li	PROPN
fnp-3528	1288	14	,	,	PUNCT
fnp-3528	1288	15	f.	f.	PROPN
fnp-3528	1288	16	;	;	PUNCT
fnp-3528	1288	17	guo	guo	PROPN
fnp-3528	1288	18	,	,	PUNCT
fnp-3528	1288	19	s.	s.	PROPN
fnp-3528	1288	20	;	;	PUNCT
fnp-3528	1288	21	song	song	PROPN
fnp-3528	1288	22	,	,	PUNCT
fnp-3528	1288	23	w.	w.	PROPN
fnp-3528	1288	24	;	;	PUNCT
fnp-3528	1288	25	zhang	zhang	PROPN
fnp-3528	1288	26	,	,	PUNCT
fnp-3528	1288	27	h.	h.	PROPN
fnp-3528	1288	28	;	;	PUNCT
fnp-3528	1288	29	liu	liu	PROPN
fnp-3528	1288	30	,	,	PUNCT
fnp-3528	1288	31	x.	x.	PROPN
fnp-3528	1288	32	;	;	PUNCT
fnp-3528	1288	33	zhang	zhang	PROPN
fnp-3528	1288	34	,	,	PUNCT
fnp-3528	1288	35	s.	s.	PROPN
fnp-3528	1288	36	;	;	PUNCT
fnp-3528	1288	37	zhang	zhang	PROPN
fnp-3528	1288	38	,	,	PUNCT
fnp-3528	1288	39	j.	j.	PROPN
fnp-3528	1288	40	;	;	PUNCT
fnp-3528	1288	41	ho	ho	PROPN
fnp-3528	1288	42	,	,	PUNCT
fnp-3528	1288	43	c.	c.	PROPN
fnp-3528	1288	44	t.	t.	PROPN
fnp-3528	1288	45	;	;	PUNCT
fnp-3528	1288	46	bai	bai	PROPN
fnp-3528	1288	47	,	,	PUNCT
fnp-3528	1288	48	n.	n.	NOUN
fnp-3528	1288	49	stilbenoids	stilbenoid	NOUN
fnp-3528	1288	50	and	and	CCONJ
fnp-3528	1288	51	cannabinoids	cannabinoid	NOUN
fnp-3528	1288	52	from	from	ADP
fnp-3528	1288	53	the	the	DET
fnp-3528	1288	54	leaves	leave	NOUN
fnp-3528	1288	55	of	of	ADP
fnp-3528	1288	56	cannabis	cannabis	NOUN
fnp-3528	1288	57	sativa	sativa	PROPN
fnp-3528	1288	58	f.	f.	PROPN
fnp-3528	1288	59	sativa	sativa	PROPN
fnp-3528	1288	60	with	with	ADP
fnp-3528	1288	61	potential	potential	ADJ
fnp-3528	1288	62	reverse	reverse	ADJ
fnp-3528	1288	63	cholesterol	cholesterol	NOUN
fnp-3528	1288	64	transport	transport	NOUN
fnp-3528	1288	65	activity	activity	NOUN
fnp-3528	1288	66	.	.	PUNCT
fnp-3528	1289	1	food	food	NOUN
fnp-3528	1289	2	funct	funct	PROPN
fnp-3528	1289	3	2018	2018	NUM
fnp-3528	1289	4	,	,	PUNCT
fnp-3528	1289	5	9	9	NUM
fnp-3528	1289	6	,	,	PUNCT
fnp-3528	1289	7	6608	6608	NUM
fnp-3528	1289	8	-	-	SYM
fnp-3528	1289	9	17	17	NUM
fnp-3528	1289	10	.	.	PUNCT
fnp-3528	1290	1	dong	dong	PROPN
fnp-3528	1290	2	,	,	PUNCT
fnp-3528	1290	3	t.	t.	PROPN
fnp-3528	1290	4	;	;	PUNCT
fnp-3528	1290	5	lyu	lyu	NOUN
fnp-3528	1290	6	,	,	PUNCT
fnp-3528	1290	7	j.	j.	PROPN
fnp-3528	1290	8	;	;	PUNCT
fnp-3528	1290	9	imachi	imachi	PROPN
fnp-3528	1290	10	,	,	PUNCT
fnp-3528	1290	11	h.	h.	PROPN
fnp-3528	1290	12	;	;	PUNCT
fnp-3528	1290	13	kobayashi	kobayashi	PROPN
fnp-3528	1290	14	,	,	PUNCT
fnp-3528	1290	15	t.	t.	PROPN
fnp-3528	1290	16	;	;	PUNCT
fnp-3528	1290	17	fukunaga	fukunaga	PROPN
fnp-3528	1290	18	,	,	PUNCT
fnp-3528	1290	19	k.	k.	PROPN
fnp-3528	1290	20	;	;	PUNCT
fnp-3528	1290	21	sato	sato	PROPN
fnp-3528	1290	22	,	,	PUNCT
fnp-3528	1290	23	s.	s.	PROPN
fnp-3528	1290	24	;	;	PUNCT
fnp-3528	1290	25	ibata	ibata	PROPN
fnp-3528	1290	26	,	,	PUNCT
fnp-3528	1290	27	t.	t.	PROPN
fnp-3528	1290	28	;	;	PUNCT
fnp-3528	1290	29	yoshimoto	yoshimoto	NOUN
fnp-3528	1290	30	,	,	PUNCT
fnp-3528	1290	31	t.	t.	PROPN
fnp-3528	1290	32	;	;	PUNCT
fnp-3528	1290	33	yonezaki	yonezaki	PROPN
fnp-3528	1290	34	,	,	PUNCT
fnp-3528	1290	35	k.	k.	PROPN
fnp-3528	1290	36	;	;	PUNCT
fnp-3528	1290	37	iwama	iwama	PROPN
fnp-3528	1290	38	,	,	PUNCT
fnp-3528	1290	39	h.	h.	PROPN
fnp-3528	1290	40	;	;	PUNCT
fnp-3528	1290	41	zhang	zhang	PROPN
fnp-3528	1290	42	,	,	PUNCT
fnp-3528	1290	43	g.	g.	PROPN
fnp-3528	1290	44	;	;	PUNCT
fnp-3528	1290	45	murao	murao	INTJ
fnp-3528	1290	46	,	,	PUNCT
fnp-3528	1290	47	k.	k.	PROPN
fnp-3528	1290	48	selective	selective	PROPN
fnp-3528	1290	49	peroxisome	peroxisome	PROPN
fnp-3528	1290	50	proliferator	proliferator	PROPN
fnp-3528	1290	51	-	-	PUNCT
fnp-3528	1290	52	activated	activate	VERB
fnp-3528	1290	53	receptor	receptor	NOUN
fnp-3528	1290	54	-	-	PUNCT
fnp-3528	1290	55	alpha	alpha	NOUN
fnp-3528	1290	56	modulator	modulator	NOUN
fnp-3528	1290	57	k-877	k-877	NOUN
fnp-3528	1290	58	regulates	regulate	VERB
fnp-3528	1290	59	the	the	DET
fnp-3528	1290	60	expression	expression	NOUN
fnp-3528	1290	61	of	of	ADP
fnp-3528	1290	62	atp	atp	NOUN
fnp-3528	1290	63	-	-	PUNCT
fnp-3528	1290	64	binding	bind	VERB
fnp-3528	1290	65	cassette	cassette	NOUN
fnp-3528	1290	66	transporter	transporter	NOUN
fnp-3528	1290	67	a1	a1	NOUN
fnp-3528	1290	68	in	in	ADP
fnp-3528	1290	69	pancreatic	pancreatic	ADJ
fnp-3528	1290	70	beta	beta	NOUN
fnp-3528	1290	71	cells	cell	NOUN
fnp-3528	1290	72	.	.	PUNCT
fnp-3528	1291	1	eur	eur	PROPN
fnp-3528	1291	2	j	j	PROPN
fnp-3528	1291	3	pharmacol	pharmacol	PROPN
fnp-3528	1291	4	2018	2018	NUM
fnp-3528	1291	5	,	,	PUNCT
fnp-3528	1291	6	838	838	NUM
fnp-3528	1291	7	,	,	PUNCT
fnp-3528	1291	8	78	78	NUM
fnp-3528	1291	9	-	-	SYM
fnp-3528	1291	10	84	84	NUM
fnp-3528	1291	11	.	.	PUNCT
fnp-3528	1292	1	wang	wang	PROPN
fnp-3528	1292	2	,	,	PUNCT
fnp-3528	1292	3	x.	x.	PROPN
fnp-3528	1292	4	;	;	PUNCT
fnp-3528	1292	5	luo	luo	PROPN
fnp-3528	1292	6	,	,	PUNCT
fnp-3528	1292	7	j.	j.	PROPN
fnp-3528	1292	8	;	;	PUNCT
fnp-3528	1292	9	li	li	PROPN
fnp-3528	1292	10	,	,	PUNCT
fnp-3528	1292	11	n.	n.	PROPN
fnp-3528	1292	12	;	;	PUNCT
fnp-3528	1292	13	liu	liu	PROPN
fnp-3528	1292	14	,	,	PUNCT
fnp-3528	1292	15	l.	l.	PROPN
fnp-3528	1292	16	;	;	PUNCT
fnp-3528	1292	17	han	han	PROPN
fnp-3528	1292	18	,	,	PUNCT
fnp-3528	1292	19	x.	x.	PROPN
fnp-3528	1292	20	;	;	PUNCT
fnp-3528	1292	21	liu	liu	PROPN
fnp-3528	1292	22	,	,	PUNCT
fnp-3528	1292	23	c.	c.	PROPN
fnp-3528	1292	24	;	;	PUNCT
fnp-3528	1292	25	zuo	zuo	PROPN
fnp-3528	1292	26	,	,	PUNCT
fnp-3528	1292	27	x.	x.	PROPN
fnp-3528	1292	28	;	;	PUNCT
fnp-3528	1292	29	jiang	jiang	PROPN
fnp-3528	1292	30	,	,	PUNCT
fnp-3528	1292	31	x.	x.	PROPN
fnp-3528	1292	32	;	;	PUNCT
fnp-3528	1292	33	li	li	PROPN
fnp-3528	1292	34	,	,	PUNCT
fnp-3528	1292	35	y.	y.	PROPN
fnp-3528	1292	36	;	;	PUNCT
fnp-3528	1292	37	xu	xu	INTJ
fnp-3528	1292	38	,	,	PUNCT
fnp-3528	1292	39	y.	y.	PROPN
fnp-3528	1292	40	;	;	PUNCT
fnp-3528	1292	41	si	si	PROPN
fnp-3528	1292	42	,	,	PUNCT
fnp-3528	1292	43	s.	s.	PROPN
fnp-3528	1292	44	e3317	e3317	NOUN
fnp-3528	1292	45	promotes	promote	VERB
fnp-3528	1292	46	cholesterol	cholesterol	NOUN
fnp-3528	1292	47	efflux	efflux	NOUN
fnp-3528	1292	48	in	in	ADP
fnp-3528	1292	49	macrophage	macrophage	ADJ
fnp-3528	1292	50	cells	cell	NOUN
fnp-3528	1292	51	via	via	ADP
fnp-3528	1292	52	enhancing	enhance	VERB
fnp-3528	1292	53	abca1	abca1	NOUN
fnp-3528	1292	54	expression	expression	NOUN
fnp-3528	1292	55	.	.	PUNCT
fnp-3528	1293	1	biochem	biochem	PROPN
fnp-3528	1293	2	biophys	biophy	VERB
fnp-3528	1293	3	res	res	PROPN
fnp-3528	1293	4	commun	commun	PROPN
fnp-3528	1293	5	2018	2018	NUM
fnp-3528	1293	6	,	,	PUNCT
fnp-3528	1293	7	504	504	NUM
fnp-3528	1293	8	,	,	PUNCT
fnp-3528	1293	9	68	68	NUM
fnp-3528	1293	10	-	-	SYM
fnp-3528	1293	11	74	74	NUM
fnp-3528	1293	12	.	.	PUNCT
fnp-3528	1294	1	silva	silva	PROPN
fnp-3528	1294	2	,	,	PUNCT
fnp-3528	1294	3	j.	j.	PROPN
fnp-3528	1294	4	c.	c.	PROPN
fnp-3528	1294	5	;	;	PUNCT
fnp-3528	1294	6	de	de	PROPN
fnp-3528	1294	7	oliveira	oliveira	PROPN
fnp-3528	1294	8	,	,	PUNCT
fnp-3528	1294	9	e.	e.	PROPN
fnp-3528	1294	10	m.	m.	PROPN
fnp-3528	1294	11	;	;	PUNCT
fnp-3528	1294	12	turato	turato	PROPN
fnp-3528	1294	13	,	,	PUNCT
fnp-3528	1294	14	w.	w.	PROPN
fnp-3528	1294	15	m.	m.	NOUN
fnp-3528	1294	16	;	;	PUNCT
fnp-3528	1294	17	trossini	trossini	PROPN
fnp-3528	1294	18	,	,	PUNCT
fnp-3528	1294	19	g.	g.	PROPN
fnp-3528	1294	20	h.	h.	PROPN
fnp-3528	1294	21	g.	g.	PROPN
fnp-3528	1294	22	;	;	PUNCT
fnp-3528	1294	23	maltarollo	maltarollo	PROPN
fnp-3528	1294	24	,	,	PUNCT
fnp-3528	1294	25	v.	v.	PROPN
fnp-3528	1294	26	g.	g.	PROPN
fnp-3528	1294	27	;	;	PUNCT
fnp-3528	1294	28	pitta	pitta	NOUN
fnp-3528	1294	29	,	,	PUNCT
fnp-3528	1294	30	m.	m.	NOUN
fnp-3528	1294	31	g.	g.	PROPN
fnp-3528	1294	32	r.	r.	PROPN
fnp-3528	1294	33	;	;	PUNCT
fnp-3528	1294	34	pitta	pitta	NOUN
fnp-3528	1294	35	,	,	PUNCT
fnp-3528	1294	36	i.	i.	PROPN
fnp-3528	1294	37	r.	r.	PROPN
fnp-3528	1294	38	;	;	PUNCT
fnp-3528	1294	39	de	de	PROPN
fnp-3528	1294	40	las	las	PROPN
fnp-3528	1294	41	heras	heras	PROPN
fnp-3528	1294	42	,	,	PUNCT
fnp-3528	1294	43	b.	b.	PROPN
fnp-3528	1294	44	;	;	PUNCT
fnp-3528	1294	45	bosca	bosca	PROPN
fnp-3528	1294	46	,	,	PUNCT
fnp-3528	1294	47	l.	l.	PROPN
fnp-3528	1294	48	;	;	PUNCT
fnp-3528	1294	49	rudnicki	rudnicki	NOUN
fnp-3528	1294	50	,	,	PUNCT
fnp-3528	1294	51	m.	m.	NOUN
fnp-3528	1294	52	;	;	PUNCT
fnp-3528	1294	53	abdalla	abdalla	PROPN
fnp-3528	1294	54	,	,	PUNCT
fnp-3528	1294	55	d.	d.	PROPN
fnp-3528	1294	56	s.	s.	PROPN
fnp-3528	1294	57	p.	p.	PROPN
fnp-3528	1294	58	gq-11	gq-11	NOUN
fnp-3528	1294	59	:	:	PUNCT
fnp-3528	1294	60	a	a	DET
fnp-3528	1294	61	new	new	ADJ
fnp-3528	1294	62	ppar	ppar	NOUN
fnp-3528	1294	63	agonist	agonist	NOUN
fnp-3528	1294	64	improves	improve	VERB
fnp-3528	1294	65	obesity	obesity	NOUN
fnp-3528	1294	66	-	-	PUNCT
fnp-3528	1294	67	induced	induce	VERB
fnp-3528	1294	68	metabolic	metabolic	NOUN
fnp-3528	1294	69	alterations	alteration	NOUN
fnp-3528	1294	70	in	in	ADP
fnp-3528	1294	71	ldlr(-/-	ldlr(-/-	NOUN
fnp-3528	1294	72	)	)	PUNCT
fnp-3528	1294	73	mice	mouse	NOUN
fnp-3528	1294	74	.	.	PUNCT
fnp-3528	1295	1	int	int	NOUN
fnp-3528	1295	2	j	j	PROPN
fnp-3528	1295	3	obes	obes	PROPN
fnp-3528	1295	4	(	(	PUNCT
fnp-3528	1295	5	lond	lond	ADJ
fnp-3528	1295	6	)	)	PUNCT
fnp-3528	1295	7	2018	2018	NUM
fnp-3528	1295	8	,	,	PUNCT
fnp-3528	1295	9	42	42	NUM
fnp-3528	1295	10	,	,	PUNCT
fnp-3528	1295	11	1062	1062	NUM
fnp-3528	1295	12	-	-	SYM
fnp-3528	1295	13	72	72	NUM
fnp-3528	1295	14	.	.	PUNCT
fnp-3528	1296	1	wang	wang	PROPN
fnp-3528	1296	2	,	,	PUNCT
fnp-3528	1296	3	s.	s.	PROPN
fnp-3528	1296	4	;	;	PUNCT
fnp-3528	1296	5	zhang	zhang	PROPN
fnp-3528	1296	6	,	,	PUNCT
fnp-3528	1296	7	x.	x.	PROPN
fnp-3528	1296	8	;	;	PUNCT
fnp-3528	1296	9	li	li	PROPN
fnp-3528	1296	10	,	,	PUNCT
fnp-3528	1296	11	x.	x.	PROPN
fnp-3528	1296	12	;	;	PUNCT
fnp-3528	1296	13	liu	liu	PROPN
fnp-3528	1296	14	,	,	PUNCT
fnp-3528	1296	15	q.	q.	PROPN
fnp-3528	1296	16	;	;	PUNCT
fnp-3528	1296	17	zhou	zhou	PROPN
fnp-3528	1296	18	,	,	PUNCT
fnp-3528	1296	19	y.	y.	PROPN
fnp-3528	1296	20	;	;	PUNCT
fnp-3528	1296	21	guo	guo	PROPN
fnp-3528	1296	22	,	,	PUNCT
fnp-3528	1296	23	p.	p.	PROPN
fnp-3528	1296	24	;	;	PUNCT
fnp-3528	1296	25	dong	dong	PROPN
fnp-3528	1296	26	,	,	PUNCT
fnp-3528	1296	27	z.	z.	PROPN
fnp-3528	1296	28	;	;	PUNCT
fnp-3528	1296	29	wu	wu	PROPN
fnp-3528	1296	30	,	,	PUNCT
fnp-3528	1296	31	c.	c.	PROPN
fnp-3528	1296	32	phenylpropanoid	phenylpropanoid	PROPN
fnp-3528	1296	33	glucosides	glucoside	NOUN
fnp-3528	1296	34	from	from	ADP
fnp-3528	1296	35	tadehagi	tadehagi	PROPN
fnp-3528	1296	36	triquetrum	triquetrum	PROPN
fnp-3528	1296	37	inhibit	inhibit	NOUN
fnp-3528	1296	38	oxldl	oxldl	NOUN
fnp-3528	1296	39	-	-	PUNCT
fnp-3528	1296	40	evoked	evoke	VERB
fnp-3528	1296	41	foam	foam	NOUN
fnp-3528	1296	42	cell	cell	NOUN
fnp-3528	1296	43	formation	formation	NOUN
fnp-3528	1296	44	through	through	ADP
fnp-3528	1296	45	modulating	modulate	VERB
fnp-3528	1296	46	cholesterol	cholesterol	NOUN
fnp-3528	1296	47	homeostasis	homeostasis	NOUN
fnp-3528	1296	48	in	in	ADP
fnp-3528	1296	49	raw264.7	raw264.7	PROPN
fnp-3528	1296	50	macrophages	macrophage	NOUN
fnp-3528	1296	51	.	.	PUNCT
fnp-3528	1297	1	nat	nat	PROPN
fnp-3528	1297	2	prod	prod	PROPN
fnp-3528	1297	3	res	re	NOUN
fnp-3528	1297	4	2019	2019	NUM
fnp-3528	1297	5	,	,	PUNCT
fnp-3528	1297	6	33	33	NUM
fnp-3528	1297	7	,	,	PUNCT
fnp-3528	1297	8	893	893	NUM
fnp-3528	1297	9	-	-	SYM
fnp-3528	1297	10	6	6	NUM
fnp-3528	1297	11	.	.	PUNCT
fnp-3528	1298	1	brunham	brunham	PROPN
fnp-3528	1298	2	,	,	PUNCT
fnp-3528	1298	3	l.	l.	PROPN
fnp-3528	1298	4	r.	r.	PROPN
fnp-3528	1298	5	;	;	PUNCT
fnp-3528	1298	6	kruit	kruit	PROPN
fnp-3528	1298	7	,	,	PUNCT
fnp-3528	1298	8	j.	j.	PROPN
fnp-3528	1298	9	k.	k.	PROPN
fnp-3528	1298	10	;	;	PUNCT
fnp-3528	1298	11	pape	pape	NOUN
fnp-3528	1298	12	,	,	PUNCT
fnp-3528	1298	13	t.	t.	PROPN
fnp-3528	1298	14	d.	d.	PROPN
fnp-3528	1298	15	;	;	PUNCT
fnp-3528	1298	16	timmins	timmins	PROPN
fnp-3528	1298	17	,	,	PUNCT
fnp-3528	1298	18	j.	j.	PROPN
fnp-3528	1298	19	m.	m.	PROPN
fnp-3528	1298	20	;	;	PUNCT
fnp-3528	1298	21	reuwer	reuwer	NOUN
fnp-3528	1298	22	,	,	PUNCT
fnp-3528	1298	23	a.	a.	NOUN
fnp-3528	1298	24	q.	q.	PROPN
fnp-3528	1298	25	;	;	PUNCT
fnp-3528	1298	26	vasanji	vasanji	PROPN
fnp-3528	1298	27	,	,	PUNCT
fnp-3528	1298	28	z.	z.	PROPN
fnp-3528	1298	29	;	;	PUNCT
fnp-3528	1298	30	marsh	marsh	PROPN
fnp-3528	1298	31	,	,	PUNCT
fnp-3528	1298	32	b.	b.	PROPN
fnp-3528	1298	33	j.	j.	PROPN
fnp-3528	1298	34	;	;	PUNCT
fnp-3528	1298	35	rodrigues	rodrigues	PROPN
fnp-3528	1298	36	,	,	PUNCT
fnp-3528	1298	37	b.	b.	PROPN
fnp-3528	1298	38	;	;	PUNCT
fnp-3528	1298	39	johnson	johnson	PROPN
fnp-3528	1298	40	,	,	PUNCT
fnp-3528	1298	41	j.	j.	PROPN
fnp-3528	1298	42	d.	d.	PROPN
fnp-3528	1298	43	;	;	PUNCT
fnp-3528	1298	44	parks	park	NOUN
fnp-3528	1298	45	,	,	PUNCT
fnp-3528	1298	46	j.	j.	PROPN
fnp-3528	1298	47	s.	s.	PROPN
fnp-3528	1298	48	;	;	PUNCT
fnp-3528	1298	49	verchere	verchere	ADV
fnp-3528	1298	50	,	,	PUNCT
fnp-3528	1298	51	c.	c.	PROPN
fnp-3528	1298	52	b.	b.	PROPN
fnp-3528	1298	53	;	;	PUNCT
fnp-3528	1298	54	hayden	hayden	PROPN
fnp-3528	1298	55	,	,	PUNCT
fnp-3528	1298	56	m.	m.	PROPN
fnp-3528	1298	57	r.	r.	PROPN
fnp-3528	1298	58	beta	beta	NOUN
fnp-3528	1298	59	-	-	PUNCT
fnp-3528	1298	60	cell	cell	NOUN
fnp-3528	1298	61	abca1	abca1	NOUN
fnp-3528	1298	62	influences	influence	VERB
fnp-3528	1298	63	insulin	insulin	NOUN
fnp-3528	1298	64	secretion	secretion	NOUN
fnp-3528	1298	65	,	,	PUNCT
fnp-3528	1298	66	glucose	glucose	NOUN
fnp-3528	1298	67	homeostasis	homeostasis	NOUN
fnp-3528	1298	68	and	and	CCONJ
fnp-3528	1298	69	response	response	NOUN
fnp-3528	1298	70	to	to	ADP
fnp-3528	1298	71	thiazolidinedione	thiazolidinedione	ADJ
fnp-3528	1298	72	treatment	treatment	NOUN
fnp-3528	1298	73	.	.	PUNCT
fnp-3528	1299	1	nat	nat	PROPN
fnp-3528	1299	2	med	med	PROPN
fnp-3528	1299	3	2007	2007	NUM
fnp-3528	1299	4	,	,	PUNCT
fnp-3528	1299	5	13	13	NUM
fnp-3528	1299	6	,	,	PUNCT
fnp-3528	1299	7	340	340	NUM
fnp-3528	1299	8	-	-	SYM
fnp-3528	1299	9	7	7	NUM
fnp-3528	1299	10	.	.	PUNCT
fnp-3528	1300	1	gao	gao	PROPN
fnp-3528	1300	2	,	,	PUNCT
fnp-3528	1300	3	q.	q.	PROPN
fnp-3528	1300	4	;	;	PUNCT
fnp-3528	1300	5	wei	wei	PROPN
fnp-3528	1300	6	,	,	PUNCT
fnp-3528	1300	7	a.	a.	PROPN
fnp-3528	1300	8	;	;	PUNCT
fnp-3528	1300	9	chen	chen	PROPN
fnp-3528	1300	10	,	,	PUNCT
fnp-3528	1300	11	f.	f.	PROPN
fnp-3528	1300	12	;	;	PUNCT
fnp-3528	1300	13	chen	chen	PROPN
fnp-3528	1300	14	,	,	PUNCT
fnp-3528	1300	15	x.	x.	PROPN
fnp-3528	1300	16	;	;	PUNCT
fnp-3528	1300	17	ding	ding	PROPN
fnp-3528	1300	18	,	,	PUNCT
fnp-3528	1300	19	w.	w.	PROPN
fnp-3528	1300	20	;	;	PUNCT
fnp-3528	1300	21	ding	ding	PROPN
fnp-3528	1300	22	,	,	PUNCT
fnp-3528	1300	23	z.	z.	PROPN
fnp-3528	1300	24	;	;	PUNCT
fnp-3528	1300	25	wu	wu	PROPN
fnp-3528	1300	26	,	,	PUNCT
fnp-3528	1300	27	z.	z.	PROPN
fnp-3528	1300	28	;	;	PUNCT
fnp-3528	1300	29	du	du	PROPN
fnp-3528	1300	30	,	,	PUNCT
fnp-3528	1300	31	r.	r.	PROPN
fnp-3528	1300	32	;	;	PUNCT
fnp-3528	1300	33	cao	cao	PROPN
fnp-3528	1300	34	,	,	PUNCT
fnp-3528	1300	35	w.	w.	NOUN
fnp-3528	1300	36	enhancing	enhance	VERB
fnp-3528	1300	37	ppargamma	ppargamma	PROPN
fnp-3528	1300	38	by	by	ADP
fnp-3528	1300	39	hdac	hdac	NOUN
fnp-3528	1300	40	inhibition	inhibition	NOUN
fnp-3528	1300	41	reduces	reduce	VERB
fnp-3528	1300	42	foam	foam	NOUN
fnp-3528	1300	43	cell	cell	NOUN
fnp-3528	1300	44	formation	formation	NOUN
fnp-3528	1300	45	and	and	CCONJ
fnp-3528	1300	46	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1300	47	in	in	ADP
fnp-3528	1300	48	apoe	apoe	ADJ
fnp-3528	1300	49	deficient	deficient	ADJ
fnp-3528	1300	50	mice	mouse	NOUN
fnp-3528	1300	51	.	.	PUNCT
fnp-3528	1301	1	pharmacol	pharmacol	NOUN
fnp-3528	1301	2	res	re	NOUN
fnp-3528	1301	3	2020	2020	NUM
fnp-3528	1301	4	,	,	PUNCT
fnp-3528	1301	5	160	160	NUM
fnp-3528	1301	6	,	,	PUNCT
fnp-3528	1301	7	105059	105059	NUM
fnp-3528	1301	8	.	.	PUNCT
fnp-3528	1302	1	farzanegan	farzanegan	PROPN
fnp-3528	1302	2	gharabolagh	gharabolagh	PROPN
fnp-3528	1302	3	,	,	PUNCT
fnp-3528	1302	4	a.	a.	NOUN
fnp-3528	1302	5	;	;	PUNCT
fnp-3528	1302	6	bamdad	bamdad	NOUN
fnp-3528	1302	7	,	,	PUNCT
fnp-3528	1302	8	t.	t.	PROPN
fnp-3528	1302	9	;	;	PUNCT
fnp-3528	1302	10	hedayati	hedayati	PROPN
fnp-3528	1302	11	,	,	PUNCT
fnp-3528	1302	12	m.	m.	NOUN
fnp-3528	1302	13	;	;	PUNCT
fnp-3528	1302	14	dehghan	dehghan	PROPN
fnp-3528	1302	15	manshadi	manshadi	NOUN
fnp-3528	1302	16	,	,	PUNCT
fnp-3528	1302	17	s.	s.	PROPN
fnp-3528	1302	18	a.	a.	PROPN
fnp-3528	1303	1	the	the	DET
fnp-3528	1303	2	synergistic	synergistic	ADJ
fnp-3528	1303	3	effect	effect	NOUN
fnp-3528	1303	4	of	of	ADP
fnp-3528	1303	5	fluvastatin	fluvastatin	NOUN
fnp-3528	1303	6	and	and	CCONJ
fnp-3528	1303	7	ifn	ifn	NOUN
fnp-3528	1303	8	-	-	PUNCT
fnp-3528	1303	9	lambda	lambda	NOUN
fnp-3528	1303	10	on	on	ADP
fnp-3528	1303	11	peripheral	peripheral	ADJ
fnp-3528	1303	12	blood	blood	NOUN
fnp-3528	1303	13	mononuclear	mononuclear	ADJ
fnp-3528	1303	14	cells	cell	NOUN
fnp-3528	1303	15	of	of	ADP
fnp-3528	1303	16	chronic	chronic	ADJ
fnp-3528	1303	17	hepatitis	hepatitis	PROPN
fnp-3528	1303	18	c	c	PROPN
fnp-3528	1303	19	virus	virus	NOUN
fnp-3528	1303	20	(	(	PUNCT
fnp-3528	1303	21	hcv	hcv	NOUN
fnp-3528	1303	22	)	)	PUNCT
fnp-3528	1303	23	patients	patient	NOUN
fnp-3528	1303	24	with	with	ADP
fnp-3528	1303	25	il-28b	il-28b	PROPN
fnp-3528	1303	26	rs12979860	rs12979860	PROPN
fnp-3528	1303	27	cc	cc	PROPN
fnp-3528	1303	28	genotype	genotype	PROPN
fnp-3528	1303	29	.	.	PUNCT
fnp-3528	1304	1	iran	iran	PROPN
fnp-3528	1304	2	j	j	PROPN
fnp-3528	1304	3	allergy	allergy	PROPN
fnp-3528	1304	4	asthma	asthma	PROPN
fnp-3528	1304	5	immunol	immunol	PROPN
fnp-3528	1304	6	2019	2019	NUM
fnp-3528	1304	7	,	,	PUNCT
fnp-3528	1304	8	18	18	NUM
fnp-3528	1304	9	,	,	PUNCT
fnp-3528	1304	10	533	533	NUM
fnp-3528	1304	11	-	-	SYM
fnp-3528	1304	12	42	42	NUM
fnp-3528	1304	13	.	.	PUNCT
fnp-3528	1305	1	wong	wong	PROPN
fnp-3528	1305	2	,	,	PUNCT
fnp-3528	1305	3	j.	j.	PROPN
fnp-3528	1305	4	;	;	PUNCT
fnp-3528	1305	5	quinn	quinn	PROPN
fnp-3528	1305	6	,	,	PUNCT
fnp-3528	1305	7	c.	c.	PROPN
fnp-3528	1305	8	m.	m.	NOUN
fnp-3528	1305	9	;	;	PUNCT
fnp-3528	1305	10	brown	brown	PROPN
fnp-3528	1305	11	,	,	PUNCT
fnp-3528	1305	12	a.	a.	PROPN
fnp-3528	1305	13	j.	j.	PROPN
fnp-3528	1305	14	statins	statins	PROPN
fnp-3528	1305	15	inhibit	inhibit	VERB
fnp-3528	1305	16	synthesis	synthesis	NOUN
fnp-3528	1305	17	of	of	ADP
fnp-3528	1305	18	an	an	DET
fnp-3528	1305	19	oxysterol	oxysterol	NOUN
fnp-3528	1305	20	ligand	ligand	NOUN
fnp-3528	1305	21	for	for	ADP
fnp-3528	1305	22	the	the	DET
fnp-3528	1305	23	liver	liver	NOUN
fnp-3528	1305	24	x	x	NOUN
fnp-3528	1305	25	receptor	receptor	NOUN
fnp-3528	1305	26	in	in	ADP
fnp-3528	1305	27	human	human	ADJ
fnp-3528	1305	28	macrophages	macrophage	NOUN
fnp-3528	1305	29	with	with	ADP
fnp-3528	1305	30	consequences	consequence	NOUN
fnp-3528	1305	31	for	for	ADP
fnp-3528	1305	32	cholesterol	cholesterol	NOUN
fnp-3528	1305	33	flux	flux	NOUN
fnp-3528	1305	34	.	.	PUNCT
fnp-3528	1306	1	arterioscler	arterioscler	PROPN
fnp-3528	1306	2	thromb	thromb	PROPN
fnp-3528	1306	3	vasc	vasc	PROPN
fnp-3528	1306	4	biol	biol	PROPN
fnp-3528	1306	5	2004	2004	NUM
fnp-3528	1306	6	,	,	PUNCT
fnp-3528	1306	7	24	24	NUM
fnp-3528	1306	8	,	,	PUNCT
fnp-3528	1306	9	2365	2365	NUM
fnp-3528	1306	10	-	-	SYM
fnp-3528	1306	11	71	71	NUM
fnp-3528	1306	12	.	.	PUNCT
fnp-3528	1307	1	pirmoradi	pirmoradi	PROPN
fnp-3528	1307	2	,	,	PUNCT
fnp-3528	1307	3	l.	l.	PROPN
fnp-3528	1307	4	;	;	PUNCT
fnp-3528	1307	5	seyfizadeh	seyfizadeh	PROPN
fnp-3528	1307	6	,	,	PUNCT
fnp-3528	1307	7	n.	n.	NOUN
fnp-3528	1307	8	;	;	PUNCT
fnp-3528	1307	9	ghavami	ghavami	NOUN
fnp-3528	1307	10	,	,	PUNCT
fnp-3528	1307	11	s.	s.	PROPN
fnp-3528	1307	12	;	;	PUNCT
fnp-3528	1307	13	zeki	zeki	PROPN
fnp-3528	1307	14	,	,	PUNCT
fnp-3528	1307	15	a.	a.	NOUN
fnp-3528	1307	16	a.	a.	NOUN
fnp-3528	1307	17	;	;	PUNCT
fnp-3528	1307	18	shojaei	shojaei	NOUN
fnp-3528	1307	19	,	,	PUNCT
fnp-3528	1307	20	s.	s.	PROPN
fnp-3528	1307	21	targeting	target	VERB
fnp-3528	1307	22	cholesterol	cholesterol	NOUN
fnp-3528	1307	23	metabolism	metabolism	NOUN
fnp-3528	1307	24	in	in	ADP
fnp-3528	1307	25	glioblastoma	glioblastoma	NOUN
fnp-3528	1307	26	:	:	PUNCT
fnp-3528	1307	27	a	a	DET
fnp-3528	1307	28	new	new	ADJ
fnp-3528	1307	29	therapeutic	therapeutic	ADJ
fnp-3528	1307	30	approach	approach	NOUN
fnp-3528	1307	31	in	in	ADP
fnp-3528	1307	32	cancer	cancer	NOUN
fnp-3528	1307	33	therapy	therapy	NOUN
fnp-3528	1307	34	.	.	PUNCT
fnp-3528	1308	1	j	j	PROPN
fnp-3528	1308	2	investig	investig	NOUN
fnp-3528	1308	3	med	med	PROPN
fnp-3528	1308	4	2019	2019	NUM
fnp-3528	1308	5	,	,	PUNCT
fnp-3528	1308	6	67	67	NUM
fnp-3528	1309	1	,	,	PUNCT
fnp-3528	1309	2	715	715	NUM
fnp-3528	1309	3	-	-	SYM
fnp-3528	1309	4	9	9	NUM
fnp-3528	1309	5	.	.	PUNCT
fnp-3528	1309	6	fu	fu	PROPN
fnp-3528	1309	7	,	,	PUNCT
fnp-3528	1309	8	y.	y.	PROPN
fnp-3528	1309	9	;	;	PUNCT
fnp-3528	1309	10	zhou	zhou	PROPN
fnp-3528	1309	11	,	,	PUNCT
fnp-3528	1309	12	e.	e.	PROPN
fnp-3528	1309	13	;	;	PUNCT
fnp-3528	1309	14	wei	wei	PROPN
fnp-3528	1309	15	,	,	PUNCT
fnp-3528	1309	16	z.	z.	PROPN
fnp-3528	1309	17	;	;	PUNCT
fnp-3528	1309	18	song	song	PROPN
fnp-3528	1309	19	,	,	PUNCT
fnp-3528	1309	20	x.	x.	PROPN
fnp-3528	1309	21	;	;	PUNCT
fnp-3528	1310	1	liu	liu	PROPN
fnp-3528	1310	2	,	,	PUNCT
fnp-3528	1310	3	z.	z.	PROPN
fnp-3528	1310	4	;	;	PUNCT
fnp-3528	1310	5	wang	wang	PROPN
fnp-3528	1310	6	,	,	PUNCT
fnp-3528	1310	7	t.	t.	PROPN
fnp-3528	1310	8	;	;	PUNCT
fnp-3528	1310	9	wang	wang	PROPN
fnp-3528	1310	10	,	,	PUNCT
fnp-3528	1310	11	w.	w.	PROPN
fnp-3528	1310	12	;	;	PUNCT
fnp-3528	1310	13	zhang	zhang	PROPN
fnp-3528	1310	14	,	,	PUNCT
fnp-3528	1310	15	n.	n.	PROPN
fnp-3528	1310	16	;	;	PUNCT
fnp-3528	1310	17	liu	liu	PROPN
fnp-3528	1310	18	,	,	PUNCT
fnp-3528	1310	19	g.	g.	PROPN
fnp-3528	1310	20	;	;	PUNCT
fnp-3528	1310	21	yang	yang	PROPN
fnp-3528	1310	22	,	,	PUNCT
fnp-3528	1310	23	z.	z.	PROPN
fnp-3528	1310	24	glycyrrhizin	glycyrrhizin	PROPN
fnp-3528	1310	25	inhibits	inhibit	VERB
fnp-3528	1310	26	lipopolysaccharide	lipopolysaccharide	ADV
fnp-3528	1310	27	-	-	PUNCT
fnp-3528	1310	28	induced	induce	VERB
fnp-3528	1310	29	inflammatory	inflammatory	ADJ
fnp-3528	1310	30	response	response	NOUN
fnp-3528	1310	31	by	by	ADP
fnp-3528	1310	32	reducing	reduce	VERB
fnp-3528	1310	33	tlr4	tlr4	NOUN
fnp-3528	1310	34	recruitment	recruitment	NOUN
fnp-3528	1310	35	into	into	ADP
fnp-3528	1310	36	lipid	lipid	ADJ
fnp-3528	1310	37	rafts	raft	NOUN
fnp-3528	1310	38	in	in	ADP
fnp-3528	1310	39	raw264.7	raw264.7	NOUN
fnp-3528	1310	40	cells	cell	NOUN
fnp-3528	1310	41	.	.	PUNCT
fnp-3528	1311	1	biochim	biochim	PROPN
fnp-3528	1311	2	biophys	biophy	NOUN
fnp-3528	1311	3	acta	acta	PROPN
fnp-3528	1311	4	2014	2014	NUM
fnp-3528	1311	5	,	,	PUNCT
fnp-3528	1311	6	1840	1840	NUM
fnp-3528	1311	7	,	,	PUNCT
fnp-3528	1311	8	1755	1755	NUM
fnp-3528	1311	9	-	-	SYM
fnp-3528	1311	10	64	64	NUM
fnp-3528	1311	11	.	.	PUNCT
fnp-3528	1312	1	singh	singh	PROPN
fnp-3528	1312	2	,	,	PUNCT
fnp-3528	1312	3	a.	a.	PROPN
fnp-3528	1312	4	b.	b.	PROPN
fnp-3528	1312	5	;	;	PUNCT
fnp-3528	1312	6	dong	dong	PROPN
fnp-3528	1312	7	,	,	PUNCT
fnp-3528	1312	8	b.	b.	PROPN
fnp-3528	1312	9	;	;	PUNCT
fnp-3528	1312	10	kraemer	kraemer	PROPN
fnp-3528	1312	11	,	,	PUNCT
fnp-3528	1312	12	f.	f.	PROPN
fnp-3528	1312	13	b.	b.	PROPN
fnp-3528	1312	14	;	;	PUNCT
fnp-3528	1312	15	liu	liu	PROPN
fnp-3528	1312	16	,	,	PUNCT
fnp-3528	1312	17	j.	j.	PROPN
fnp-3528	1312	18	fxr	fxr	PROPN
fnp-3528	1312	19	activation	activation	NOUN
fnp-3528	1312	20	promotes	promote	VERB
fnp-3528	1312	21	intestinal	intestinal	ADJ
fnp-3528	1312	22	cholesterol	cholesterol	NOUN
fnp-3528	1312	23	excretion	excretion	NOUN
fnp-3528	1312	24	and	and	CCONJ
fnp-3528	1312	25	attenuates	attenuate	VERB
fnp-3528	1312	26	hyperlipidemia	hyperlipidemia	NOUN
fnp-3528	1312	27	in	in	ADP
fnp-3528	1312	28	sr	sr	PROPN
fnp-3528	1312	29	-	-	PUNCT
fnp-3528	1312	30	b1	b1	ADJ
fnp-3528	1312	31	-	-	PUNCT
fnp-3528	1312	32	deficient	deficient	ADJ
fnp-3528	1312	33	mice	mouse	NOUN
fnp-3528	1312	34	fed	feed	VERB
fnp-3528	1312	35	a	a	DET
fnp-3528	1312	36	high	high	ADJ
fnp-3528	1312	37	-	-	PUNCT
fnp-3528	1312	38	fat	fat	NOUN
fnp-3528	1312	39	and	and	CCONJ
fnp-3528	1312	40	high	high	ADJ
fnp-3528	1312	41	-	-	PUNCT
fnp-3528	1312	42	cholesterol	cholesterol	NOUN
fnp-3528	1312	43	diet	diet	NOUN
fnp-3528	1312	44	.	.	PUNCT
fnp-3528	1313	1	physiol	physiol	PROPN
fnp-3528	1313	2	rep	rep	PROPN
fnp-3528	1313	3	2020	2020	NUM
fnp-3528	1313	4	,	,	PUNCT
fnp-3528	1313	5	8	8	NUM
fnp-3528	1313	6	,	,	PUNCT
fnp-3528	1313	7	e14387	e14387	PROPN
fnp-3528	1313	8	.	.	PUNCT
fnp-3528	1314	1	yang	yang	PROPN
fnp-3528	1314	2	,	,	PUNCT
fnp-3528	1314	3	y.	y.	PROPN
fnp-3528	1314	4	;	;	PUNCT
fnp-3528	1314	5	li	li	PROPN
fnp-3528	1314	6	,	,	PUNCT
fnp-3528	1314	7	x.	x.	PROPN
fnp-3528	1314	8	;	;	PUNCT
fnp-3528	1314	9	peng	peng	PROPN
fnp-3528	1314	10	,	,	PUNCT
fnp-3528	1314	11	l.	l.	PROPN
fnp-3528	1314	12	;	;	PUNCT
fnp-3528	1314	13	an	an	PRON
fnp-3528	1314	14	,	,	PUNCT
fnp-3528	1314	15	l.	l.	PROPN
fnp-3528	1314	16	;	;	PUNCT
fnp-3528	1314	17	sun	sun	NOUN
fnp-3528	1314	18	,	,	PUNCT
fnp-3528	1314	19	n.	n.	NOUN
fnp-3528	1314	20	;	;	PUNCT
fnp-3528	1314	21	hu	hu	PROPN
fnp-3528	1314	22	,	,	PUNCT
fnp-3528	1314	23	x.	x.	PROPN
fnp-3528	1314	24	;	;	PUNCT
fnp-3528	1314	25	zhou	zhou	PROPN
fnp-3528	1314	26	,	,	PUNCT
fnp-3528	1314	27	p.	p.	PROPN
fnp-3528	1314	28	;	;	PUNCT
fnp-3528	1314	29	xu	xu	INTJ
fnp-3528	1314	30	,	,	PUNCT
fnp-3528	1314	31	y.	y.	PROPN
fnp-3528	1314	32	;	;	PUNCT
fnp-3528	1314	33	li	li	PROPN
fnp-3528	1314	34	,	,	PUNCT
fnp-3528	1314	35	p.	p.	PROPN
fnp-3528	1314	36	;	;	PUNCT
fnp-3528	1314	37	chen	chen	PROPN
fnp-3528	1314	38	,	,	PUNCT
fnp-3528	1314	39	j.	j.	PROPN
fnp-3528	1314	40	tanshindiol	tanshindiol	PROPN
fnp-3528	1314	41	c	c	PROPN
fnp-3528	1314	42	inhibits	inhibits	AUX
fnp-3528	1314	43	oxidized	oxidize	VERB
fnp-3528	1314	44	low	low	ADJ
fnp-3528	1314	45	-	-	PUNCT
fnp-3528	1314	46	density	density	NOUN
fnp-3528	1314	47	lipoprotein	lipoprotein	ADJ
fnp-3528	1314	48	induced	induce	VERB
fnp-3528	1314	49	macrophage	macrophage	ADJ
fnp-3528	1314	50	foam	foam	NOUN
fnp-3528	1314	51	cell	cell	NOUN
fnp-3528	1314	52	formation	formation	NOUN
fnp-3528	1314	53	via	via	ADP
fnp-3528	1314	54	a	a	DET
fnp-3528	1314	55	peroxiredoxin	peroxiredoxin	NOUN
fnp-3528	1314	56	1	1	NUM
fnp-3528	1314	57	dependent	dependent	ADJ
fnp-3528	1314	58	pathway	pathway	NOUN
fnp-3528	1314	59	.	.	PUNCT
fnp-3528	1315	1	biochim	biochim	PROPN
fnp-3528	1315	2	biophys	biophy	NOUN
fnp-3528	1315	3	acta	acta	PROPN
fnp-3528	1315	4	mol	mol	ADP
fnp-3528	1315	5	basis	basis	NOUN
fnp-3528	1315	6	dis	dis	PROPN
fnp-3528	1315	7	2018	2018	NUM
fnp-3528	1315	8	,	,	PUNCT
fnp-3528	1315	9	1864	1864	NUM
fnp-3528	1315	10	,	,	PUNCT
fnp-3528	1315	11	882	882	NUM
fnp-3528	1315	12	-	-	SYM
fnp-3528	1315	13	90	90	NUM
fnp-3528	1315	14	.	.	PUNCT
fnp-3528	1316	1	koga	koga	PROPN
fnp-3528	1316	2	,	,	PUNCT
fnp-3528	1316	3	m.	m.	NOUN
fnp-3528	1316	4	;	;	PUNCT
fnp-3528	1316	5	kanaoka	kanaoka	NOUN
fnp-3528	1316	6	,	,	PUNCT
fnp-3528	1316	7	y.	y.	PROPN
fnp-3528	1316	8	;	;	PUNCT
fnp-3528	1316	9	inada	inada	PROPN
fnp-3528	1316	10	,	,	PUNCT
fnp-3528	1316	11	k.	k.	PROPN
fnp-3528	1316	12	;	;	PUNCT
fnp-3528	1316	13	omine	omine	PROPN
fnp-3528	1316	14	,	,	PUNCT
fnp-3528	1316	15	s.	s.	PROPN
fnp-3528	1316	16	;	;	PUNCT
fnp-3528	1316	17	kataoka	kataoka	PROPN
fnp-3528	1316	18	,	,	PUNCT
fnp-3528	1316	19	y.	y.	PROPN
fnp-3528	1316	20	;	;	PUNCT
fnp-3528	1316	21	yamauchi	yamauchi	PROPN
fnp-3528	1316	22	,	,	PUNCT
fnp-3528	1316	23	a.	a.	NOUN
fnp-3528	1316	24	hesperidin	hesperidin	NOUN
fnp-3528	1316	25	blocks	block	VERB
fnp-3528	1316	26	varenicline	varenicline	NOUN
fnp-3528	1316	27	-	-	PUNCT
fnp-3528	1316	28	aggravated	aggravate	VERB
fnp-3528	1316	29	atherosclerotic	atherosclerotic	ADJ
fnp-3528	1316	30	plaque	plaque	NOUN
fnp-3528	1316	31	formation	formation	NOUN
fnp-3528	1316	32	in	in	ADP
fnp-3528	1316	33	apolipoprotein	apolipoprotein	ADJ
fnp-3528	1316	34	e	e	NOUN
fnp-3528	1316	35	knockout	knockout	NOUN
fnp-3528	1316	36	mice	mouse	NOUN
fnp-3528	1316	37	by	by	ADP
fnp-3528	1316	38	downregulating	downregulate	VERB
fnp-3528	1316	39	net	net	ADJ
fnp-3528	1316	40	uptake	uptake	NOUN
fnp-3528	1316	41	of	of	ADP
fnp-3528	1316	42	oxidized	oxidize	VERB
fnp-3528	1316	43	low	low	ADJ
fnp-3528	1316	44	-	-	PUNCT
fnp-3528	1316	45	density	density	NOUN
fnp-3528	1316	46	lipoprotein	lipoprotein	NOUN
fnp-3528	1316	47	in	in	ADP
fnp-3528	1316	48	macrophages	macrophage	NOUN
fnp-3528	1316	49	.	.	PUNCT
fnp-3528	1317	1	j	j	PROPN
fnp-3528	1317	2	pharmacol	pharmacol	PROPN
fnp-3528	1317	3	sci	sci	PROPN
fnp-3528	1317	4	2020	2020	NUM
fnp-3528	1317	5	,	,	PUNCT
fnp-3528	1317	6	143	143	NUM
fnp-3528	1317	7	,	,	PUNCT
fnp-3528	1317	8	106	106	NUM
fnp-3528	1317	9	-	-	SYM
fnp-3528	1317	10	11	11	NUM
fnp-3528	1317	11	.	.	PUNCT
fnp-3528	1318	1	han	han	PROPN
fnp-3528	1318	2	,	,	PUNCT
fnp-3528	1318	3	q.	q.	PROPN
fnp-3528	1318	4	a.	a.	PROPN
fnp-3528	1318	5	;	;	PUNCT
fnp-3528	1318	6	su	su	PROPN
fnp-3528	1318	7	,	,	PUNCT
fnp-3528	1318	8	d.	d.	PROPN
fnp-3528	1318	9	;	;	PUNCT
fnp-3528	1318	10	shi	shi	PROPN
fnp-3528	1318	11	,	,	PUNCT
fnp-3528	1318	12	c.	c.	PROPN
fnp-3528	1318	13	;	;	PUNCT
fnp-3528	1318	14	liu	liu	PROPN
fnp-3528	1318	15	,	,	PUNCT
fnp-3528	1318	16	p.	p.	PROPN
fnp-3528	1318	17	;	;	PUNCT
fnp-3528	1318	18	wang	wang	PROPN
fnp-3528	1318	19	,	,	PUNCT
fnp-3528	1318	20	y.	y.	PROPN
fnp-3528	1318	21	;	;	PUNCT
fnp-3528	1318	22	zhu	zhu	PROPN
fnp-3528	1318	23	,	,	PUNCT
fnp-3528	1318	24	b.	b.	PROPN
fnp-3528	1318	25	;	;	PUNCT
fnp-3528	1318	26	xia	xia	PROPN
fnp-3528	1318	27	,	,	PUNCT
fnp-3528	1318	28	x.	x.	PROPN
fnp-3528	1318	29	urolithin	urolithin	PROPN
fnp-3528	1318	30	a	a	DET
fnp-3528	1318	31	attenuated	attenuate	VERB
fnp-3528	1318	32	ox	ox	ADJ
fnp-3528	1318	33	-	-	ADJ
fnp-3528	1318	34	ldl	ldl	ADJ
fnp-3528	1318	35	-	-	PUNCT
fnp-3528	1318	36	induced	induce	VERB
fnp-3528	1318	37	cholesterol	cholesterol	NOUN
fnp-3528	1318	38	accumulation	accumulation	NOUN
fnp-3528	1318	39	in	in	ADP
fnp-3528	1318	40	macrophages	macrophage	NOUN
fnp-3528	1318	41	partly	partly	ADV
fnp-3528	1318	42	through	through	ADP
fnp-3528	1318	43	regulating	regulate	VERB
fnp-3528	1318	44	mir-33a	mir-33a	NUM
fnp-3528	1318	45	and	and	CCONJ
fnp-3528	1318	46	erk	erk	NOUN
fnp-3528	1318	47	/	/	SYM
fnp-3528	1318	48	ampk	ampk	NOUN
fnp-3528	1318	49	/	/	SYM
fnp-3528	1318	50	srebp1	srebp1	NOUN
fnp-3528	1318	51	signaling	signal	VERB
fnp-3528	1318	52	pathways	pathway	NOUN
fnp-3528	1318	53	.	.	PUNCT
fnp-3528	1319	1	food	food	NOUN
fnp-3528	1319	2	funct	funct	PROPN
fnp-3528	1319	3	2020	2020	NUM
fnp-3528	1319	4	,	,	PUNCT
fnp-3528	1319	5	11	11	NUM
fnp-3528	1319	6	,	,	PUNCT
fnp-3528	1319	7	3432	3432	NUM
fnp-3528	1319	8	-	-	SYM
fnp-3528	1319	9	40	40	NUM
fnp-3528	1319	10	.	.	PUNCT
fnp-3528	1320	1	du	du	PROPN
fnp-3528	1320	2	,	,	PUNCT
fnp-3528	1320	3	y.	y.	PROPN
fnp-3528	1320	4	;	;	PUNCT
fnp-3528	1320	5	li	li	PROPN
fnp-3528	1320	6	,	,	PUNCT
fnp-3528	1320	7	x.	x.	PROPN
fnp-3528	1320	8	;	;	PUNCT
fnp-3528	1320	9	su	su	PROPN
fnp-3528	1320	10	,	,	PUNCT
fnp-3528	1320	11	c.	c.	PROPN
fnp-3528	1320	12	;	;	PUNCT
fnp-3528	1320	13	xi	xi	PROPN
fnp-3528	1320	14	,	,	PUNCT
fnp-3528	1320	15	m.	m.	NOUN
fnp-3528	1320	16	;	;	PUNCT
fnp-3528	1320	17	zhang	zhang	PROPN
fnp-3528	1320	18	,	,	PUNCT
fnp-3528	1320	19	x.	x.	PROPN
fnp-3528	1320	20	;	;	PUNCT
fnp-3528	1320	21	jiang	jiang	PROPN
fnp-3528	1320	22	,	,	PUNCT
fnp-3528	1320	23	z.	z.	PROPN
fnp-3528	1320	24	;	;	PUNCT
fnp-3528	1320	25	wang	wang	PROPN
fnp-3528	1320	26	,	,	PUNCT
fnp-3528	1320	27	l.	l.	PROPN
fnp-3528	1320	28	;	;	PUNCT
fnp-3528	1320	29	hong	hong	PROPN
fnp-3528	1320	30	,	,	PUNCT
fnp-3528	1320	31	b.	b.	PROPN
fnp-3528	1320	32	butyrate	butyrate	PROPN
fnp-3528	1320	33	protects	protect	VERB
fnp-3528	1320	34	against	against	ADP
fnp-3528	1320	35	high	high	ADJ
fnp-3528	1320	36	-	-	PUNCT
fnp-3528	1320	37	fat	fat	NOUN
fnp-3528	1320	38	diet	diet	NOUN
fnp-3528	1320	39	-	-	PUNCT
fnp-3528	1320	40	induced	induce	VERB
fnp-3528	1320	41	atherosclerosis	atherosclerosis	NOUN
fnp-3528	1320	42	via	via	ADP
fnp-3528	1320	43	up	up	ADV
fnp-3528	1320	44	-	-	PUNCT
fnp-3528	1320	45	regulating	regulate	VERB
fnp-3528	1320	46	abca1	abca1	NOUN
fnp-3528	1320	47	expression	expression	NOUN
fnp-3528	1320	48	in	in	ADP
fnp-3528	1320	49	apolipoprotein	apolipoprotein	ADJ
fnp-3528	1320	50	e	e	NOUN
fnp-3528	1320	51	-	-	NOUN
fnp-3528	1320	52	deficiency	deficiency	NOUN
fnp-3528	1320	53	mice	mouse	NOUN
fnp-3528	1320	54	.	.	PUNCT
fnp-3528	1321	1	br	br	PROPN
fnp-3528	1322	1	j	j	PROPN
fnp-3528	1322	2	pharmacol	pharmacol	PROPN
fnp-3528	1322	3	2020	2020	NUM
fnp-3528	1322	4	,	,	PUNCT
fnp-3528	1322	5	177	177	NUM
fnp-3528	1322	6	,	,	PUNCT
fnp-3528	1322	7	1754	1754	NUM
fnp-3528	1322	8	-	-	SYM
fnp-3528	1322	9	72	72	NUM
fnp-3528	1322	10	.	.	PUNCT
fnp-3528	1323	1	wang	wang	PROPN
fnp-3528	1323	2	,	,	PUNCT
fnp-3528	1323	3	l.	l.	PROPN
fnp-3528	1323	4	;	;	PUNCT
fnp-3528	1323	5	zhu	zhu	PROPN
fnp-3528	1323	6	,	,	PUNCT
fnp-3528	1323	7	j.	j.	PROPN
fnp-3528	1323	8	;	;	PUNCT
fnp-3528	1323	9	cui	cui	PROPN
fnp-3528	1323	10	,	,	PUNCT
fnp-3528	1323	11	l.	l.	PROPN
fnp-3528	1323	12	;	;	PUNCT
fnp-3528	1323	13	wang	wang	PROPN
fnp-3528	1323	14	,	,	PUNCT
fnp-3528	1323	15	q.	q.	PROPN
fnp-3528	1323	16	;	;	PUNCT
fnp-3528	1323	17	huang	huang	PROPN
fnp-3528	1323	18	,	,	PUNCT
fnp-3528	1323	19	w.	w.	PROPN
fnp-3528	1323	20	;	;	PUNCT
fnp-3528	1323	21	ji	ji	PROPN
fnp-3528	1323	22	,	,	PUNCT
fnp-3528	1323	23	x.	x.	PROPN
fnp-3528	1323	24	;	;	PUNCT
fnp-3528	1323	25	yang	yang	PROPN
fnp-3528	1323	26	,	,	PUNCT
fnp-3528	1323	27	q.	q.	PROPN
fnp-3528	1323	28	;	;	PUNCT
fnp-3528	1323	29	rui	rui	PROPN
fnp-3528	1323	30	,	,	PUNCT
fnp-3528	1323	31	c.	c.	PROPN
fnp-3528	1323	32	overexpression	overexpression	NOUN
fnp-3528	1323	33	of	of	ADP
fnp-3528	1323	34	atp	atp	NOUN
fnp-3528	1323	35	-	-	PUNCT
fnp-3528	1323	36	binding	bind	VERB
fnp-3528	1323	37	cassette	cassette	NOUN
fnp-3528	1323	38	transporters	transporter	NOUN
fnp-3528	1323	39	associated	associate	VERB
fnp-3528	1323	40	with	with	ADP
fnp-3528	1323	41	sulfoxaflor	sulfoxaflor	NOUN
fnp-3528	1323	42	resistance	resistance	NOUN
fnp-3528	1323	43	in	in	ADP
fnp-3528	1323	44	aphis	aphis	PROPN
fnp-3528	1323	45	gossypii	gossypii	PROPN
fnp-3528	1323	46	glover	glover	PROPN
fnp-3528	1323	47	.	.	PUNCT
fnp-3528	1323	48	pest	pest	PROPN
fnp-3528	1323	49	manag	manag	VERB
fnp-3528	1323	50	sci	sci	PROPN
fnp-3528	1323	51	2021	2021	NUM
fnp-3528	1323	52	,	,	PUNCT
fnp-3528	1323	53	77	77	NUM
fnp-3528	1323	54	,	,	PUNCT
fnp-3528	1323	55	4064	4064	NUM
fnp-3528	1323	56	-	-	SYM
fnp-3528	1323	57	72	72	NUM
fnp-3528	1323	58	.	.	PUNCT
fnp-3528	1324	1	song	song	PROPN
fnp-3528	1324	2	,	,	PUNCT
fnp-3528	1324	3	q.	q.	PROPN
fnp-3528	1324	4	;	;	PUNCT
fnp-3528	1324	5	hu	hu	PROPN
fnp-3528	1324	6	,	,	PUNCT
fnp-3528	1324	7	z.	z.	PROPN
fnp-3528	1324	8	;	;	PUNCT
fnp-3528	1324	9	xie	xie	PROPN
fnp-3528	1324	10	,	,	PUNCT
fnp-3528	1324	11	x.	x.	PROPN
fnp-3528	1324	12	;	;	PUNCT
fnp-3528	1324	13	cai	cai	PROPN
fnp-3528	1324	14	,	,	PUNCT
fnp-3528	1324	15	h.	h.	PROPN
fnp-3528	1324	16	zafirlukast	zafirlukast	PROPN
fnp-3528	1324	17	prevented	prevent	VERB
fnp-3528	1324	18	ox	ox	ADJ
fnp-3528	1324	19	-	-	ADJ
fnp-3528	1324	20	ldl	ldl	ADJ
fnp-3528	1324	21	-	-	PUNCT
fnp-3528	1324	22	induced	induced	ADJ
fnp-3528	1324	23	formation	formation	NOUN
fnp-3528	1324	24	of	of	ADP
fnp-3528	1324	25	foam	foam	NOUN
fnp-3528	1324	26	cells	cell	NOUN
fnp-3528	1324	27	.	.	PUNCT
fnp-3528	1325	1	toxicol	toxicol	PROPN
fnp-3528	1325	2	appl	appl	PROPN
fnp-3528	1325	3	pharmacol	pharmacol	PROPN
fnp-3528	1325	4	2020	2020	NUM
fnp-3528	1325	5	,	,	PUNCT
fnp-3528	1325	6	409	409	NUM
fnp-3528	1325	7	,	,	PUNCT
fnp-3528	1325	8	115295	115295	NUM
fnp-3528	1325	9	.	.	PUNCT
fnp-3528	1326	1	tomioka	tomioka	NOUN
fnp-3528	1326	2	,	,	PUNCT
fnp-3528	1326	3	m.	m.	NOUN
fnp-3528	1326	4	;	;	PUNCT
fnp-3528	1326	5	toda	toda	PROPN
fnp-3528	1326	6	,	,	PUNCT
fnp-3528	1326	7	y.	y.	PROPN
fnp-3528	1326	8	;	;	PUNCT
fnp-3528	1326	9	manucat	manucat	PROPN
fnp-3528	1326	10	,	,	PUNCT
fnp-3528	1326	11	n.	n.	PROPN
fnp-3528	1326	12	b.	b.	PROPN
fnp-3528	1326	13	;	;	PUNCT
fnp-3528	1326	14	akatsu	akatsu	PROPN
fnp-3528	1326	15	,	,	PUNCT
fnp-3528	1326	16	h.	h.	PROPN
fnp-3528	1326	17	;	;	PUNCT
fnp-3528	1326	18	fukumoto	fukumoto	NOUN
fnp-3528	1326	19	,	,	PUNCT
fnp-3528	1326	20	m.	m.	NOUN
fnp-3528	1326	21	;	;	PUNCT
fnp-3528	1326	22	kono	kono	NOUN
fnp-3528	1326	23	,	,	PUNCT
fnp-3528	1326	24	n.	n.	NOUN
fnp-3528	1326	25	;	;	PUNCT
fnp-3528	1326	26	arai	arai	PROPN
fnp-3528	1326	27	,	,	PUNCT
fnp-3528	1326	28	h.	h.	PROPN
fnp-3528	1326	29	;	;	PUNCT
fnp-3528	1326	30	kioka	kioka	NOUN
fnp-3528	1326	31	,	,	PUNCT
fnp-3528	1326	32	n.	n.	NOUN
fnp-3528	1326	33	;	;	PUNCT
fnp-3528	1326	34	ueda	ueda	PROPN
fnp-3528	1326	35	,	,	PUNCT
fnp-3528	1326	36	k.	k.	PROPN
fnp-3528	1326	37	lysophosphatidylcholine	lysophosphatidylcholine	PROPN
fnp-3528	1326	38	export	export	NOUN
fnp-3528	1326	39	by	by	ADP
fnp-3528	1326	40	human	human	ADJ
fnp-3528	1326	41	abca7	abca7	PROPN
fnp-3528	1326	42	.	.	PUNCT
fnp-3528	1327	1	biochim	biochim	PROPN
fnp-3528	1327	2	biophys	biophy	NOUN
fnp-3528	1327	3	acta	acta	PROPN
fnp-3528	1327	4	mol	mol	ADP
fnp-3528	1327	5	cell	cell	NOUN
fnp-3528	1327	6	biol	biol	NOUN
fnp-3528	1327	7	lipids	lipid	VERB
fnp-3528	1327	8	2017	2017	NUM
fnp-3528	1327	9	,	,	PUNCT
fnp-3528	1327	10	1862	1862	NUM
fnp-3528	1327	11	,	,	PUNCT
fnp-3528	1327	12	658	658	NUM
fnp-3528	1327	13	-	-	SYM
fnp-3528	1327	14	65	65	NUM
fnp-3528	1327	15	.	.	PUNCT
fnp-3528	1328	1	fan	fan	PROPN
fnp-3528	1328	2	,	,	PUNCT
fnp-3528	1328	3	j.	j.	PROPN
fnp-3528	1328	4	;	;	PUNCT
fnp-3528	1328	5	zhao	zhao	PROPN
fnp-3528	1328	6	,	,	PUNCT
fnp-3528	1328	7	r.	r.	PROPN
fnp-3528	1328	8	q.	q.	PROPN
fnp-3528	1328	9	;	;	PUNCT
fnp-3528	1328	10	parro	parro	PROPN
fnp-3528	1328	11	,	,	PUNCT
fnp-3528	1328	12	c.	c.	PROPN
fnp-3528	1328	13	;	;	PUNCT
fnp-3528	1328	14	zhao	zhao	PROPN
fnp-3528	1328	15	,	,	PUNCT
fnp-3528	1328	16	w.	w.	PROPN
fnp-3528	1328	17	;	;	PUNCT
fnp-3528	1328	18	chou	chou	NOUN
fnp-3528	1328	19	,	,	PUNCT
fnp-3528	1328	20	h.	h.	PROPN
fnp-3528	1328	21	y.	y.	PROPN
fnp-3528	1328	22	;	;	PUNCT
fnp-3528	1328	23	robert	robert	PROPN
fnp-3528	1328	24	,	,	PUNCT
fnp-3528	1328	25	j.	j.	PROPN
fnp-3528	1328	26	;	;	PUNCT
fnp-3528	1328	27	deeb	deeb	PROPN
fnp-3528	1328	28	,	,	PUNCT
fnp-3528	1328	29	t.	t.	PROPN
fnp-3528	1328	30	z.	z.	PROPN
fnp-3528	1328	31	;	;	PUNCT
fnp-3528	1328	32	raynoschek	raynoschek	PROPN
fnp-3528	1328	33	,	,	PUNCT
fnp-3528	1328	34	c.	c.	PROPN
fnp-3528	1328	35	;	;	PUNCT
fnp-3528	1328	36	barichievy	barichievy	ADV
fnp-3528	1328	37	,	,	PUNCT
fnp-3528	1328	38	s.	s.	PROPN
fnp-3528	1328	39	;	;	PUNCT
fnp-3528	1328	40	engkvist	engkvist	NOUN
fnp-3528	1328	41	,	,	PUNCT
fnp-3528	1328	42	o.	o.	INTJ
fnp-3528	1328	43	;	;	PUNCT
fnp-3528	1328	44	maresca	maresca	INTJ
fnp-3528	1328	45	,	,	PUNCT
fnp-3528	1328	46	m.	m.	NOUN
fnp-3528	1328	47	;	;	PUNCT
fnp-3528	1328	48	hicks	hicks	PROPN
fnp-3528	1328	49	,	,	PUNCT
fnp-3528	1328	50	r.	r.	PROPN
fnp-3528	1328	51	;	;	PUNCT
fnp-3528	1328	52	meuller	meuller	NOUN
fnp-3528	1328	53	,	,	PUNCT
fnp-3528	1328	54	j.	j.	PROPN
fnp-3528	1328	55	;	;	PUNCT
fnp-3528	1328	56	moss	moss	PROPN
fnp-3528	1328	57	,	,	PUNCT
fnp-3528	1328	58	s.	s.	PROPN
fnp-3528	1328	59	j.	j.	PROPN
fnp-3528	1328	60	;	;	PUNCT
fnp-3528	1328	61	brandon	brandon	PROPN
fnp-3528	1328	62	,	,	PUNCT
fnp-3528	1328	63	n.	n.	PROPN
fnp-3528	1328	64	j.	j.	PROPN
fnp-3528	1328	65	;	;	PUNCT
fnp-3528	1328	66	wood	wood	PROPN
fnp-3528	1328	67	,	,	PUNCT
fnp-3528	1328	68	m.	m.	NOUN
fnp-3528	1328	69	w.	w.	PROPN
fnp-3528	1328	70	;	;	PUNCT
fnp-3528	1328	71	kulic	kulic	PROPN
fnp-3528	1328	72	,	,	PUNCT
fnp-3528	1328	73	i.	i.	PROPN
fnp-3528	1328	74	;	;	PUNCT
fnp-3528	1328	75	wellington	wellington	PROPN
fnp-3528	1328	76	,	,	PUNCT
fnp-3528	1328	77	c.	c.	PROPN
fnp-3528	1328	78	l.	l.	PROPN
fnp-3528	1328	79	small	small	ADJ
fnp-3528	1328	80	molecule	molecule	NOUN
fnp-3528	1328	81	inducers	inducer	NOUN
fnp-3528	1328	82	of	of	ADP
fnp-3528	1328	83	abca1	abca1	NOUN
fnp-3528	1328	84	and	and	CCONJ
fnp-3528	1328	85	apoe	apoe	NOUN
fnp-3528	1328	86	that	that	DET
fnp-3528	1328	87	act	act	NOUN
fnp-3528	1328	88	through	through	ADP
fnp-3528	1328	89	indirect	indirect	ADJ
fnp-3528	1328	90	activation	activation	NOUN
fnp-3528	1328	91	of	of	ADP
fnp-3528	1328	92	the	the	DET
fnp-3528	1328	93	lxr	lxr	ADJ
fnp-3528	1328	94	pathway	pathway	NOUN
fnp-3528	1328	95	.	.	PUNCT
fnp-3528	1329	1	j	j	PROPN
fnp-3528	1329	2	lipid	lipid	PROPN
fnp-3528	1329	3	res	re	VERB
fnp-3528	1329	4	2018	2018	NUM
fnp-3528	1329	5	,	,	PUNCT
fnp-3528	1329	6	59	59	NUM
fnp-3528	1329	7	,	,	PUNCT
fnp-3528	1329	8	830	830	NUM
fnp-3528	1329	9	-	-	SYM
fnp-3528	1329	10	42	42	NUM
fnp-3528	1329	11	.	.	PUNCT
fnp-3528	1330	1	liu	liu	PROPN
fnp-3528	1330	2	,	,	PUNCT
fnp-3528	1330	3	j.	j.	PROPN
fnp-3528	1330	4	;	;	PUNCT
fnp-3528	1330	5	yang	yang	PROPN
fnp-3528	1330	6	,	,	PUNCT
fnp-3528	1330	7	b.	b.	PROPN
fnp-3528	1330	8	;	;	PUNCT
fnp-3528	1330	9	wang	wang	PROPN
fnp-3528	1330	10	,	,	PUNCT
fnp-3528	1330	11	y.	y.	PROPN
fnp-3528	1330	12	;	;	PUNCT
fnp-3528	1330	13	wu	wu	PROPN
fnp-3528	1330	14	,	,	PUNCT
fnp-3528	1330	15	y.	y.	PROPN
fnp-3528	1330	16	;	;	PUNCT
fnp-3528	1330	17	fan	fan	PROPN
fnp-3528	1330	18	,	,	PUNCT
fnp-3528	1330	19	b.	b.	PROPN
fnp-3528	1330	20	;	;	PUNCT
fnp-3528	1330	21	zhu	zhu	PROPN
fnp-3528	1330	22	,	,	PUNCT
fnp-3528	1330	23	s.	s.	PROPN
fnp-3528	1330	24	;	;	PUNCT
fnp-3528	1330	25	song	song	PROPN
fnp-3528	1330	26	,	,	PUNCT
fnp-3528	1330	27	e.	e.	PROPN
fnp-3528	1330	28	;	;	PUNCT
fnp-3528	1330	29	song	song	PROPN
fnp-3528	1330	30	,	,	PUNCT
fnp-3528	1330	31	y.	y.	PROPN
fnp-3528	1330	32	polychlorinated	polychlorinate	VERB
fnp-3528	1330	33	biphenyl	biphenyl	NOUN
fnp-3528	1330	34	quinone	quinone	NOUN
fnp-3528	1330	35	promotes	promote	VERB
fnp-3528	1330	36	macrophage	macrophage	ADJ
fnp-3528	1330	37	polarization	polarization	NOUN
fnp-3528	1330	38	to	to	ADP
fnp-3528	1330	39	cd163(+	cd163(+	PROPN
fnp-3528	1330	40	)	)	PUNCT
fnp-3528	1330	41	cells	cell	NOUN
fnp-3528	1330	42	through	through	ADP
fnp-3528	1330	43	nrf2	nrf2	NOUN
fnp-3528	1330	44	signaling	signal	VERB
fnp-3528	1330	45	pathway	pathway	NOUN
fnp-3528	1330	46	.	.	PUNCT
fnp-3528	1331	1	environ	environ	PROPN
fnp-3528	1331	2	pollut	pollut	VERB
fnp-3528	1331	3	2020	2020	NUM
fnp-3528	1331	4	,	,	PUNCT
fnp-3528	1331	5	257	257	NUM
fnp-3528	1331	6	,	,	PUNCT
fnp-3528	1331	7	113587	113587	NUM
fnp-3528	1331	8	.	.	PUNCT
fnp-3528	1332	1	chen	chen	PROPN
fnp-3528	1332	2	,	,	PUNCT
fnp-3528	1332	3	x.	x.	PROPN
fnp-3528	1332	4	;	;	PUNCT
fnp-3528	1332	5	su	su	PROPN
fnp-3528	1332	6	,	,	PUNCT
fnp-3528	1332	7	l.	l.	PROPN
fnp-3528	1332	8	;	;	PUNCT
fnp-3528	1332	9	yang	yang	PROPN
fnp-3528	1332	10	,	,	PUNCT
fnp-3528	1332	11	y.	y.	PROPN
fnp-3528	1332	12	;	;	PUNCT
fnp-3528	1332	13	qv	qv	PROPN
fnp-3528	1332	14	,	,	PUNCT
fnp-3528	1332	15	j.	j.	PROPN
fnp-3528	1332	16	;	;	PUNCT
fnp-3528	1332	17	wei	wei	PROPN
fnp-3528	1332	18	,	,	PUNCT
fnp-3528	1332	19	t.	t.	PROPN
fnp-3528	1332	20	;	;	PUNCT
fnp-3528	1332	21	cui	cui	PROPN
fnp-3528	1332	22	,	,	PUNCT
fnp-3528	1332	23	x.	x.	PROPN
fnp-3528	1332	24	;	;	PUNCT
fnp-3528	1332	25	shao	shao	PROPN
fnp-3528	1332	26	,	,	PUNCT
fnp-3528	1332	27	j.	j.	PROPN
fnp-3528	1332	28	;	;	PUNCT
fnp-3528	1332	29	liu	liu	PROPN
fnp-3528	1332	30	,	,	PUNCT
fnp-3528	1332	31	s.	s.	PROPN
fnp-3528	1332	32	;	;	PUNCT
fnp-3528	1332	33	xu	xu	PROPN
fnp-3528	1332	34	,	,	PUNCT
fnp-3528	1332	35	z.	z.	PROPN
fnp-3528	1332	36	;	;	PUNCT
fnp-3528	1332	37	zhao	zhao	PROPN
fnp-3528	1332	38	,	,	PUNCT
fnp-3528	1332	39	b.	b.	PROPN
fnp-3528	1332	40	;	;	PUNCT
fnp-3528	1332	41	miao	miao	PROPN
fnp-3528	1332	42	,	,	PUNCT
fnp-3528	1332	43	j.	j.	PROPN
fnp-3528	1332	44	a	a	DET
fnp-3528	1332	45	new	new	ADJ
fnp-3528	1332	46	activator	activator	NOUN
fnp-3528	1332	47	of	of	ADP
fnp-3528	1332	48	esterase	esterase	NOUN
fnp-3528	1332	49	d	d	PROPN
fnp-3528	1332	50	decreases	decrease	VERB
fnp-3528	1332	51	blood	blood	NOUN
fnp-3528	1332	52	cholesterol	cholesterol	NOUN
fnp-3528	1332	53	level	level	NOUN
fnp-3528	1332	54	through	through	ADP
fnp-3528	1332	55	esd	esd	PROPN
fnp-3528	1332	56	/	/	SYM
fnp-3528	1332	57	jab1	jab1	PROPN
fnp-3528	1332	58	/	/	SYM
fnp-3528	1332	59	abca1	abca1	NOUN
fnp-3528	1332	60	pathway	pathway	NOUN
fnp-3528	1332	61	.	.	PUNCT
fnp-3528	1333	1	j	j	PROPN
fnp-3528	1333	2	cell	cell	PROPN
fnp-3528	1333	3	physiol	physiol	PROPN
fnp-3528	1333	4	2021	2021	NUM
fnp-3528	1333	5	,	,	PUNCT
fnp-3528	1333	6	236	236	NUM
fnp-3528	1333	7	,	,	PUNCT
fnp-3528	1333	8	4750	4750	NUM
fnp-3528	1333	9	-	-	SYM
fnp-3528	1333	10	63	63	NUM
fnp-3528	1333	11	.	.	PUNCT
fnp-3528	1334	1	hupfeld	hupfeld	ADJ
fnp-3528	1334	2	,	,	PUNCT
fnp-3528	1334	3	t.	t.	PROPN
fnp-3528	1334	4	;	;	PUNCT
fnp-3528	1334	5	chapuy	chapuy	NOUN
fnp-3528	1334	6	,	,	PUNCT
fnp-3528	1334	7	b.	b.	PROPN
fnp-3528	1334	8	;	;	PUNCT
fnp-3528	1334	9	schrader	schrader	PROPN
fnp-3528	1334	10	,	,	PUNCT
fnp-3528	1334	11	v.	v.	ADV
fnp-3528	1334	12	;	;	PUNCT
fnp-3528	1334	13	beutler	beutler	NOUN
fnp-3528	1334	14	,	,	PUNCT
fnp-3528	1334	15	m.	m.	NOUN
fnp-3528	1334	16	;	;	PUNCT
fnp-3528	1334	17	veltkamp	veltkamp	NOUN
fnp-3528	1334	18	,	,	PUNCT
fnp-3528	1334	19	c.	c.	PROPN
fnp-3528	1334	20	;	;	PUNCT
fnp-3528	1334	21	koch	koch	PROPN
fnp-3528	1334	22	,	,	PUNCT
fnp-3528	1334	23	r.	r.	PROPN
fnp-3528	1334	24	;	;	PUNCT
fnp-3528	1334	25	cameron	cameron	PROPN
fnp-3528	1334	26	,	,	PUNCT
fnp-3528	1334	27	s.	s.	PROPN
fnp-3528	1334	28	;	;	PUNCT
fnp-3528	1334	29	aung	aung	PROPN
fnp-3528	1334	30	,	,	PUNCT
fnp-3528	1334	31	t.	t.	PROPN
fnp-3528	1334	32	;	;	PUNCT
fnp-3528	1334	33	haase	haase	PROPN
fnp-3528	1334	34	,	,	PUNCT
fnp-3528	1334	35	d.	d.	PROPN
fnp-3528	1334	36	;	;	PUNCT
fnp-3528	1334	37	larosee	larosee	PROPN
fnp-3528	1334	38	,	,	PUNCT
fnp-3528	1334	39	p.	p.	NOUN
fnp-3528	1334	40	;	;	PUNCT
fnp-3528	1334	41	truemper	truemper	X
fnp-3528	1334	42	,	,	PUNCT
fnp-3528	1334	43	l.	l.	PROPN
fnp-3528	1334	44	;	;	PUNCT
fnp-3528	1334	45	wulf	wulf	PROPN
fnp-3528	1334	46	,	,	PUNCT
fnp-3528	1334	47	g.	g.	PROPN
fnp-3528	1334	48	g.	g.	PROPN
fnp-3528	1334	49	tyrosinekinase	tyrosinekinase	PROPN
fnp-3528	1334	50	inhibition	inhibition	NOUN
fnp-3528	1334	51	facilitates	facilitate	VERB
fnp-3528	1334	52	cooperation	cooperation	NOUN
fnp-3528	1334	53	of	of	ADP
fnp-3528	1334	54	transcription	transcription	NOUN
fnp-3528	1334	55	factor	factor	NOUN
fnp-3528	1334	56	sall4	sall4	PROPN
fnp-3528	1334	57	and	and	CCONJ
fnp-3528	1334	58	abc	abc	PROPN
fnp-3528	1334	59	transporter	transporter	NOUN
fnp-3528	1334	60	a3	a3	NOUN
fnp-3528	1334	61	towards	towards	ADP
fnp-3528	1334	62	intrinsic	intrinsic	ADJ
fnp-3528	1334	63	cml	cml	PROPN
fnp-3528	1334	64	cell	cell	NOUN
fnp-3528	1334	65	drug	drug	NOUN
fnp-3528	1334	66	resistance	resistance	NOUN
fnp-3528	1334	67	.	.	PUNCT
fnp-3528	1335	1	br	br	PROPN
fnp-3528	1335	2	j	j	PROPN
fnp-3528	1335	3	haematol	haematol	NOUN
fnp-3528	1335	4	2013	2013	NUM
fnp-3528	1335	5	,	,	PUNCT
fnp-3528	1335	6	161	161	NUM
fnp-3528	1335	7	,	,	PUNCT
fnp-3528	1335	8	204	204	NUM
fnp-3528	1335	9	-	-	SYM
fnp-3528	1335	10	13	13	NUM
fnp-3528	1335	11	.	.	PUNCT
fnp-3528	1336	1	sribenja	sribenja	ADJ
fnp-3528	1336	2	,	,	PUNCT
fnp-3528	1336	3	s.	s.	PROPN
fnp-3528	1336	4	;	;	PUNCT
fnp-3528	1336	5	natthasirikul	natthasirikul	NOUN
fnp-3528	1336	6	,	,	PUNCT
fnp-3528	1336	7	n.	n.	NOUN
fnp-3528	1336	8	;	;	PUNCT
fnp-3528	1336	9	vaeteewoottacharn	vaeteewoottacharn	NOUN
fnp-3528	1336	10	,	,	PUNCT
fnp-3528	1336	11	k.	k.	PROPN
fnp-3528	1336	12	;	;	PUNCT
fnp-3528	1336	13	sawanyawisuth	sawanyawisuth	ADV
fnp-3528	1336	14	,	,	PUNCT
fnp-3528	1336	15	k.	k.	PROPN
fnp-3528	1336	16	;	;	PUNCT
fnp-3528	1336	17	wongkham	wongkham	PROPN
fnp-3528	1336	18	,	,	PUNCT
fnp-3528	1336	19	c.	c.	PROPN
fnp-3528	1336	20	;	;	PUNCT
fnp-3528	1336	21	jearanaikoon	jearanaikoon	ADV
fnp-3528	1336	22	,	,	PUNCT
fnp-3528	1336	23	p.	p.	NOUN
fnp-3528	1336	24	;	;	PUNCT
fnp-3528	1336	25	wongkham	wongkham	PROPN
fnp-3528	1336	26	,	,	PUNCT
fnp-3528	1336	27	s.	s.	PROPN
fnp-3528	1336	28	thymosin	thymosin	PROPN
fnp-3528	1336	29	beta10	beta10	PROPN
fnp-3528	1336	30	as	as	ADP
fnp-3528	1336	31	a	a	DET
fnp-3528	1336	32	predictive	predictive	ADJ
fnp-3528	1336	33	biomarker	biomarker	NOUN
fnp-3528	1336	34	of	of	ADP
fnp-3528	1336	35	response	response	NOUN
fnp-3528	1336	36	to	to	ADP
fnp-3528	1336	37	5	5	NUM
fnp-3528	1336	38	-	-	PUNCT
fnp-3528	1336	39	fluorouracil	fluorouracil	NOUN
fnp-3528	1336	40	chemotherapy	chemotherapy	NOUN
fnp-3528	1336	41	in	in	ADP
fnp-3528	1336	42	cholangiocarcinoma	cholangiocarcinoma	NOUN
fnp-3528	1336	43	.	.	PUNCT
fnp-3528	1337	1	ann	ann	PROPN
fnp-3528	1338	1	hepatol	hepatol	ADJ
fnp-3528	1338	2	2016	2016	NUM
fnp-3528	1338	3	,	,	PUNCT
fnp-3528	1338	4	15	15	NUM
fnp-3528	1338	5	,	,	PUNCT
fnp-3528	1338	6	577	577	NUM
fnp-3528	1338	7	-	-	SYM
fnp-3528	1338	8	85	85	NUM
fnp-3528	1338	9	.	.	PUNCT
fnp-3528	1339	1	quezada	quezada	PROPN
fnp-3528	1339	2	,	,	PUNCT
fnp-3528	1339	3	c.	c.	PROPN
fnp-3528	1339	4	a.	a.	PROPN
fnp-3528	1339	5	;	;	PUNCT
fnp-3528	1339	6	garrido	garrido	PROPN
fnp-3528	1339	7	,	,	PUNCT
fnp-3528	1339	8	w.	w.	PROPN
fnp-3528	1339	9	x.	x.	PROPN
fnp-3528	1339	10	;	;	PUNCT
fnp-3528	1339	11	gonzalez	gonzalez	PROPN
fnp-3528	1339	12	-	-	PUNCT
fnp-3528	1339	13	oyarzun	oyarzun	PROPN
fnp-3528	1339	14	,	,	PUNCT
fnp-3528	1339	15	m.	m.	NOUN
fnp-3528	1339	16	a.	a.	NOUN
fnp-3528	1339	17	;	;	PUNCT
fnp-3528	1339	18	rauch	rauch	PROPN
fnp-3528	1339	19	,	,	PUNCT
fnp-3528	1339	20	m.	m.	PROPN
fnp-3528	1339	21	c.	c.	PROPN
fnp-3528	1339	22	;	;	PUNCT
fnp-3528	1339	23	salas	sala	NOUN
fnp-3528	1339	24	,	,	PUNCT
fnp-3528	1339	25	m.	m.	PROPN
fnp-3528	1339	26	r.	r.	PROPN
fnp-3528	1339	27	;	;	PUNCT
fnp-3528	1339	28	san	san	PROPN
fnp-3528	1339	29	martin	martin	PROPN
fnp-3528	1339	30	,	,	PUNCT
fnp-3528	1339	31	r.	r.	PROPN
fnp-3528	1339	32	e.	e.	PROPN
fnp-3528	1339	33	;	;	PUNCT
fnp-3528	1339	34	claude	claude	PROPN
fnp-3528	1339	35	,	,	PUNCT
fnp-3528	1339	36	a.	a.	NOUN
fnp-3528	1339	37	a.	a.	PROPN
fnp-3528	1339	38	;	;	PUNCT
fnp-3528	1339	39	yanez	yanez	PROPN
fnp-3528	1339	40	,	,	PUNCT
fnp-3528	1339	41	a.	a.	PROPN
fnp-3528	1339	42	j.	j.	PROPN
fnp-3528	1339	43	;	;	PUNCT
fnp-3528	1339	44	slebe	slebe	PROPN
fnp-3528	1339	45	,	,	PUNCT
fnp-3528	1339	46	j.	j.	PROPN
fnp-3528	1339	47	c.	c.	PROPN
fnp-3528	1339	48	;	;	PUNCT
fnp-3528	1339	49	carcamo	carcamo	PROPN
fnp-3528	1339	50	,	,	PUNCT
fnp-3528	1339	51	j.	j.	PROPN
fnp-3528	1339	52	g.	g.	PROPN
fnp-3528	1339	53	effect	effect	NOUN
fnp-3528	1339	54	of	of	ADP
fnp-3528	1339	55	tacrolimus	tacrolimus	NOUN
fnp-3528	1339	56	on	on	ADP
fnp-3528	1339	57	activity	activity	NOUN
fnp-3528	1339	58	and	and	CCONJ
fnp-3528	1339	59	expression	expression	NOUN
fnp-3528	1339	60	of	of	ADP
fnp-3528	1339	61	p	p	NOUN
fnp-3528	1339	62	-	-	PUNCT
fnp-3528	1339	63	glycoprotein	glycoprotein	NOUN
fnp-3528	1339	64	and	and	CCONJ
fnp-3528	1339	65	atp	atp	NOUN
fnp-3528	1339	66	-	-	PUNCT
fnp-3528	1339	67	binding	bind	VERB
fnp-3528	1339	68	cassette	cassette	NOUN
fnp-3528	1339	69	transporter	transporter	NOUN
fnp-3528	1339	70	a5	a5	NOUN
fnp-3528	1339	71	(	(	PUNCT
fnp-3528	1339	72	abca5	abca5	ADJ
fnp-3528	1339	73	)	)	PUNCT
fnp-3528	1339	74	proteins	protein	NOUN
fnp-3528	1339	75	in	in	ADP
fnp-3528	1339	76	hematoencephalic	hematoencephalic	ADJ
fnp-3528	1339	77	barrier	barrier	NOUN
fnp-3528	1339	78	cells	cell	NOUN
fnp-3528	1339	79	.	.	PUNCT
fnp-3528	1340	1	biol	biol	PROPN
fnp-3528	1340	2	pharm	pharm	PROPN
fnp-3528	1340	3	bull	bull	PROPN
fnp-3528	1340	4	2008	2008	NUM
fnp-3528	1340	5	,	,	PUNCT
fnp-3528	1340	6	31	31	NUM
fnp-3528	1340	7	,	,	PUNCT
fnp-3528	1340	8	1911	1911	NUM
fnp-3528	1340	9	-	-	SYM
fnp-3528	1340	10	6	6	NUM
fnp-3528	1340	11	.	.	PUNCT
fnp-3528	1341	1	gai	gai	PROPN
fnp-3528	1341	2	,	,	PUNCT
fnp-3528	1341	3	j.	j.	PROPN
fnp-3528	1341	4	;	;	PUNCT
fnp-3528	1341	5	ji	ji	PROPN
fnp-3528	1341	6	,	,	PUNCT
fnp-3528	1341	7	m.	m.	NOUN
fnp-3528	1341	8	;	;	PUNCT
fnp-3528	1341	9	shi	shi	PROPN
fnp-3528	1341	10	,	,	PUNCT
fnp-3528	1341	11	c.	c.	PROPN
fnp-3528	1341	12	;	;	PUNCT
fnp-3528	1341	13	li	li	PROPN
fnp-3528	1341	14	,	,	PUNCT
fnp-3528	1341	15	w.	w.	PROPN
fnp-3528	1341	16	;	;	PUNCT
fnp-3528	1341	17	chen	chen	PROPN
fnp-3528	1341	18	,	,	PUNCT
fnp-3528	1341	19	s.	s.	PROPN
fnp-3528	1341	20	;	;	PUNCT
fnp-3528	1341	21	wang	wang	PROPN
fnp-3528	1341	22	,	,	PUNCT
fnp-3528	1341	23	y.	y.	PROPN
fnp-3528	1341	24	;	;	PUNCT
fnp-3528	1341	25	li	li	PROPN
fnp-3528	1341	26	,	,	PUNCT
fnp-3528	1341	27	h.	h.	PROPN
fnp-3528	1341	28	foxo	foxo	PROPN
fnp-3528	1341	29	regulates	regulate	VERB
fnp-3528	1341	30	expression	expression	NOUN
fnp-3528	1341	31	of	of	ADP
fnp-3528	1341	32	abca6	abca6	PROPN
fnp-3528	1341	33	,	,	PUNCT
fnp-3528	1341	34	an	an	DET
fnp-3528	1341	35	intracellular	intracellular	ADJ
fnp-3528	1341	36	atp	atp	NOUN
fnp-3528	1341	37	-	-	PUNCT
fnp-3528	1341	38	binding	binding	ADJ
fnp-3528	1341	39	-	-	PUNCT
fnp-3528	1341	40	cassette	cassette	NOUN
fnp-3528	1341	41	transporter	transporter	NOUN
fnp-3528	1341	42	responsive	responsive	ADJ
fnp-3528	1341	43	to	to	ADP
fnp-3528	1341	44	cholesterol	cholesterol	NOUN
fnp-3528	1341	45	.	.	PUNCT
fnp-3528	1342	1	int	int	PROPN
fnp-3528	1342	2	j	j	PROPN
fnp-3528	1342	3	biochem	biochem	PROPN
fnp-3528	1342	4	cell	cell	NOUN
fnp-3528	1342	5	biol	biol	PROPN
fnp-3528	1342	6	2013	2013	NUM
fnp-3528	1342	7	,	,	PUNCT
fnp-3528	1342	8	45	45	NUM
fnp-3528	1342	9	,	,	PUNCT
fnp-3528	1342	10	2651	2651	NUM
fnp-3528	1342	11	-	-	SYM
fnp-3528	1342	12	9	9	NUM
fnp-3528	1342	13	.	.	X
fnp-3528	1343	1	wang	wang	PROPN
fnp-3528	1343	2	,	,	PUNCT
fnp-3528	1343	3	x.	x.	PROPN
fnp-3528	1343	4	;	;	PUNCT
fnp-3528	1343	5	cao	cao	PROPN
fnp-3528	1343	6	,	,	PUNCT
fnp-3528	1343	7	c.	c.	PROPN
fnp-3528	1343	8	;	;	PUNCT
fnp-3528	1343	9	li	li	PROPN
fnp-3528	1343	10	,	,	PUNCT
fnp-3528	1343	11	y.	y.	PROPN
fnp-3528	1343	12	;	;	PUNCT
fnp-3528	1343	13	hai	hai	PROPN
fnp-3528	1343	14	,	,	PUNCT
fnp-3528	1343	15	t.	t.	PROPN
fnp-3528	1343	16	;	;	PUNCT
fnp-3528	1343	17	jia	jia	PROPN
fnp-3528	1343	18	,	,	PUNCT
fnp-3528	1343	19	q.	q.	PROPN
fnp-3528	1343	20	;	;	PUNCT
fnp-3528	1343	21	zhang	zhang	PROPN
fnp-3528	1343	22	,	,	PUNCT
fnp-3528	1343	23	y.	y.	PROPN
fnp-3528	1343	24	;	;	PUNCT
fnp-3528	1343	25	zheng	zheng	PROPN
fnp-3528	1343	26	,	,	PUNCT
fnp-3528	1343	27	q.	q.	PROPN
fnp-3528	1343	28	;	;	PUNCT
fnp-3528	1343	29	yao	yao	PROPN
fnp-3528	1343	30	,	,	PUNCT
fnp-3528	1343	31	j.	j.	PROPN
fnp-3528	1343	32	;	;	PUNCT
fnp-3528	1343	33	qin	qin	PROPN
fnp-3528	1343	34	,	,	PUNCT
fnp-3528	1343	35	g.	g.	PROPN
fnp-3528	1343	36	;	;	PUNCT
fnp-3528	1343	37	zhang	zhang	PROPN
fnp-3528	1343	38	,	,	PUNCT
fnp-3528	1343	39	h.	h.	PROPN
fnp-3528	1343	40	;	;	PUNCT
fnp-3528	1343	41	song	song	PROPN
fnp-3528	1343	42	,	,	PUNCT
fnp-3528	1343	43	r.	r.	PROPN
fnp-3528	1343	44	;	;	PUNCT
fnp-3528	1343	45	wang	wang	PROPN
fnp-3528	1343	46	,	,	PUNCT
fnp-3528	1343	47	y.	y.	PROPN
fnp-3528	1343	48	;	;	PUNCT
fnp-3528	1343	49	shui	shui	PROPN
fnp-3528	1343	50	,	,	PUNCT
fnp-3528	1343	51	g.	g.	PROPN
fnp-3528	1343	52	;	;	PUNCT
fnp-3528	1343	53	lam	lam	PROPN
fnp-3528	1343	54	,	,	PUNCT
fnp-3528	1343	55	s.	s.	PROPN
fnp-3528	1343	56	m.	m.	PROPN
fnp-3528	1343	57	;	;	PUNCT
fnp-3528	1343	58	liu	liu	PROPN
fnp-3528	1343	59	,	,	PUNCT
fnp-3528	1343	60	z.	z.	PROPN
fnp-3528	1343	61	;	;	PUNCT
fnp-3528	1343	62	wei	wei	PROPN
fnp-3528	1343	63	,	,	PUNCT
fnp-3528	1343	64	h.	h.	PROPN
fnp-3528	1343	65	;	;	PUNCT
fnp-3528	1343	66	meng	meng	PROPN
fnp-3528	1343	67	,	,	PUNCT
fnp-3528	1343	68	a.	a.	NOUN
fnp-3528	1343	69	;	;	PUNCT
fnp-3528	1343	70	zhou	zhou	PROPN
fnp-3528	1343	71	,	,	PUNCT
fnp-3528	1343	72	q.	q.	PROPN
fnp-3528	1343	73	;	;	PUNCT
fnp-3528	1343	74	zhao	zhao	PROPN
fnp-3528	1343	75	,	,	PUNCT
fnp-3528	1343	76	j.	j.	PROPN
fnp-3528	1343	77	a	a	DET
fnp-3528	1343	78	harlequin	harlequin	PROPN
fnp-3528	1343	79	ichthyosis	ichthyosis	NOUN
fnp-3528	1343	80	pig	pig	NOUN
fnp-3528	1343	81	model	model	NOUN
fnp-3528	1343	82	with	with	ADP
fnp-3528	1343	83	a	a	DET
fnp-3528	1343	84	novel	novel	ADJ
fnp-3528	1343	85	abca12	abca12	NOUN
fnp-3528	1343	86	mutation	mutation	NOUN
fnp-3528	1343	87	can	can	AUX
fnp-3528	1343	88	be	be	AUX
fnp-3528	1343	89	rescued	rescue	VERB
fnp-3528	1343	90	by	by	ADP
fnp-3528	1343	91	acitretin	acitretin	ADJ
fnp-3528	1343	92	treatment	treatment	NOUN
fnp-3528	1343	93	.	.	PUNCT
fnp-3528	1344	1	j	j	PROPN
fnp-3528	1344	2	mol	mol	PROPN
fnp-3528	1344	3	cell	cell	NOUN
fnp-3528	1344	4	biol	biol	NOUN
fnp-3528	1344	5	2019	2019	NUM
fnp-3528	1344	6	,	,	PUNCT
fnp-3528	1344	7	11	11	NUM
fnp-3528	1344	8	,	,	PUNCT
fnp-3528	1344	9	1029	1029	NUM
fnp-3528	1344	10	-	-	SYM
fnp-3528	1344	11	41	41	NUM
fnp-3528	1344	12	.	.	PUNCT
fnp-3528	1345	1	tanaka	tanaka	PROPN
fnp-3528	1345	2	,	,	PUNCT
fnp-3528	1345	3	n.	n.	PROPN
fnp-3528	1345	4	;	;	PUNCT
fnp-3528	1345	5	abe	abe	PROPN
fnp-3528	1345	6	-	-	PUNCT
fnp-3528	1345	7	dohmae	dohmae	PROPN
fnp-3528	1345	8	,	,	PUNCT
fnp-3528	1345	9	s.	s.	PROPN
fnp-3528	1345	10	;	;	PUNCT
fnp-3528	1345	11	iwamoto	iwamoto	ADJ
fnp-3528	1345	12	,	,	PUNCT
fnp-3528	1345	13	n.	n.	NOUN
fnp-3528	1345	14	;	;	PUNCT
fnp-3528	1345	15	fitzgerald	fitzgerald	PROPN
fnp-3528	1345	16	,	,	PUNCT
fnp-3528	1345	17	m.	m.	NOUN
fnp-3528	1345	18	l.	l.	PROPN
fnp-3528	1345	19	;	;	PUNCT
fnp-3528	1345	20	yokoyama	yokoyama	PROPN
fnp-3528	1345	21	,	,	PUNCT
fnp-3528	1345	22	s.	s.	PROPN
fnp-3528	1345	23	hmg	hmg	PROPN
fnp-3528	1345	24	-	-	PUNCT
fnp-3528	1345	25	coa	coa	PROPN
fnp-3528	1345	26	reductase	reductase	NOUN
fnp-3528	1345	27	inhibitors	inhibitor	NOUN
fnp-3528	1345	28	enhance	enhance	VERB
fnp-3528	1345	29	phagocytosis	phagocytosis	NOUN
fnp-3528	1345	30	by	by	ADP
fnp-3528	1345	31	upregulating	upregulating	ADJ
fnp-3528	1345	32	atp	atp	PROPN
fnp-3528	1345	33	-	-	PUNCT
fnp-3528	1345	34	binding	bind	VERB
fnp-3528	1345	35	cassette	cassette	NOUN
fnp-3528	1345	36	transporter	transporter	NOUN
fnp-3528	1345	37	a7	a7	VERB
fnp-3528	1345	38	.	.	PUNCT
fnp-3528	1346	1	atheroscler	atheroscler	PROPN
fnp-3528	1346	2	2011	2011	NUM
fnp-3528	1346	3	,	,	PUNCT
fnp-3528	1346	4	217	217	NUM
fnp-3528	1346	5	,	,	PUNCT
fnp-3528	1346	6	407	407	NUM
fnp-3528	1346	7	-	-	SYM
fnp-3528	1346	8	14	14	NUM
fnp-3528	1346	9	.	.	PUNCT
fnp-3528	1347	1	akisato	akisato	PROPN
fnp-3528	1347	2	,	,	PUNCT
fnp-3528	1347	3	y.	y.	PROPN
fnp-3528	1347	4	;	;	PUNCT
fnp-3528	1347	5	ishii	ishii	PROPN
fnp-3528	1347	6	,	,	PUNCT
fnp-3528	1347	7	i.	i.	NOUN
fnp-3528	1347	8	;	;	PUNCT
fnp-3528	1347	9	kitahara	kitahara	PROPN
fnp-3528	1347	10	,	,	PUNCT
fnp-3528	1347	11	m.	m.	NOUN
fnp-3528	1347	12	;	;	PUNCT
fnp-3528	1347	13	tamaki	tamaki	NOUN
fnp-3528	1347	14	,	,	PUNCT
fnp-3528	1347	15	t.	t.	PROPN
fnp-3528	1347	16	;	;	PUNCT
fnp-3528	1347	17	saito	saito	PROPN
fnp-3528	1347	18	,	,	PUNCT
fnp-3528	1347	19	y.	y.	PROPN
fnp-3528	1347	20	;	;	PUNCT
fnp-3528	1347	21	kitada	kitada	PROPN
fnp-3528	1347	22	,	,	PUNCT
fnp-3528	1347	23	m.	m.	NOUN
fnp-3528	1348	1	[	[	X
fnp-3528	1348	2	effect	effect	NOUN
fnp-3528	1348	3	of	of	ADP
fnp-3528	1348	4	pitavastatin	pitavastatin	NOUN
fnp-3528	1348	5	on	on	ADP
fnp-3528	1348	6	macrophage	macrophage	ADJ
fnp-3528	1348	7	cholesterol	cholesterol	NOUN
fnp-3528	1348	8	metabolism	metabolism	NOUN
fnp-3528	1348	9	]	]	PUNCT
fnp-3528	1348	10	.	.	PUNCT
fnp-3528	1349	1	yakugaku	yakugaku	PROPN
fnp-3528	1349	2	zasshi	zasshi	PROPN
fnp-3528	1349	3	2008	2008	NUM
fnp-3528	1349	4	,	,	PUNCT
fnp-3528	1349	5	128	128	NUM
fnp-3528	1349	6	,	,	PUNCT
fnp-3528	1349	7	357	357	NUM
fnp-3528	1349	8	-	-	SYM
fnp-3528	1349	9	63	63	NUM
fnp-3528	1349	10	.	.	PUNCT
fnp-3528	1350	1	zhang	zhang	PROPN
fnp-3528	1350	2	,	,	PUNCT
fnp-3528	1350	3	y.	y.	PROPN
fnp-3528	1350	4	;	;	PUNCT
fnp-3528	1350	5	hu	hu	PROPN
fnp-3528	1350	6	,	,	PUNCT
fnp-3528	1350	7	z.	z.	PROPN
fnp-3528	1350	8	;	;	PUNCT
fnp-3528	1350	9	ye	ye	NUM
fnp-3528	1350	10	,	,	PUNCT
fnp-3528	1350	11	m.	m.	NOUN
fnp-3528	1350	12	;	;	PUNCT
fnp-3528	1350	13	pan	pan	PROPN
fnp-3528	1350	14	,	,	PUNCT
fnp-3528	1350	15	y.	y.	PROPN
fnp-3528	1350	16	;	;	PUNCT
fnp-3528	1350	17	chen	chen	PROPN
fnp-3528	1350	18	,	,	PUNCT
fnp-3528	1350	19	j.	j.	PROPN
fnp-3528	1350	20	;	;	PUNCT
fnp-3528	1350	21	luo	luo	PROPN
fnp-3528	1350	22	,	,	PUNCT
fnp-3528	1350	23	y.	y.	PROPN
fnp-3528	1350	24	;	;	PUNCT
fnp-3528	1350	25	zhang	zhang	PROPN
fnp-3528	1350	26	,	,	PUNCT
fnp-3528	1350	27	y.	y.	PROPN
fnp-3528	1350	28	;	;	PUNCT
fnp-3528	1350	29	he	he	PRON
fnp-3528	1350	30	,	,	PUNCT
fnp-3528	1350	31	l.	l.	PROPN
fnp-3528	1350	32	;	;	PUNCT
fnp-3528	1350	33	wang	wang	PROPN
fnp-3528	1350	34	,	,	PUNCT
fnp-3528	1350	35	j.	j.	PROPN
fnp-3528	1350	36	effect	effect	NOUN
fnp-3528	1350	37	of	of	ADP
fnp-3528	1350	38	poly(ethylene	poly(ethylene	PROPN
fnp-3528	1350	39	glycol)-block	glycol)-block	NOUN
fnp-3528	1350	40	-	-	PUNCT
fnp-3528	1350	41	polylactide	polylactide	NOUN
fnp-3528	1350	42	nanoparticles	nanoparticle	NOUN
fnp-3528	1350	43	on	on	ADP
fnp-3528	1350	44	hepatic	hepatic	ADJ
fnp-3528	1350	45	cells	cell	NOUN
fnp-3528	1350	46	of	of	ADP
fnp-3528	1350	47	mouse	mouse	NOUN
fnp-3528	1350	48	:	:	PUNCT
fnp-3528	1350	49	low	low	ADJ
fnp-3528	1350	50	cytotoxicity	cytotoxicity	NOUN
fnp-3528	1350	51	,	,	PUNCT
fnp-3528	1350	52	but	but	CCONJ
fnp-3528	1350	53	efflux	efflux	VERB
fnp-3528	1350	54	of	of	ADP
fnp-3528	1350	55	the	the	DET
fnp-3528	1350	56	nanoparticles	nanoparticle	NOUN
fnp-3528	1350	57	by	by	ADP
fnp-3528	1350	58	atp	atp	NOUN
fnp-3528	1350	59	-	-	PUNCT
fnp-3528	1350	60	binding	bind	VERB
fnp-3528	1350	61	cassette	cassette	NOUN
fnp-3528	1350	62	transporters	transporter	NOUN
fnp-3528	1350	63	.	.	PUNCT
fnp-3528	1351	1	eur	eur	PROPN
fnp-3528	1351	2	j	j	PROPN
fnp-3528	1351	3	pharm	pharm	PROPN
fnp-3528	1351	4	biopharm	biopharm	PROPN
fnp-3528	1351	5	2007	2007	NUM
fnp-3528	1351	6	,	,	PUNCT
fnp-3528	1351	7	66	66	NUM
fnp-3528	1351	8	,	,	PUNCT
fnp-3528	1351	9	268	268	NUM
fnp-3528	1351	10	-	-	SYM
fnp-3528	1351	11	80	80	NUM
fnp-3528	1351	12	.	.	PUNCT
fnp-3528	1352	1	jiang	jiang	PROPN
fnp-3528	1352	2	,	,	PUNCT
fnp-3528	1352	3	y.	y.	PROPN
fnp-3528	1352	4	j.	j.	PROPN
fnp-3528	1352	5	;	;	PUNCT
fnp-3528	1352	6	lu	lu	PROPN
fnp-3528	1352	7	,	,	PUNCT
fnp-3528	1352	8	b.	b.	PROPN
fnp-3528	1352	9	;	;	PUNCT
fnp-3528	1352	10	kim	kim	PROPN
fnp-3528	1352	11	,	,	PUNCT
fnp-3528	1352	12	p.	p.	PROPN
fnp-3528	1352	13	;	;	PUNCT
fnp-3528	1352	14	paragh	paragh	PROPN
fnp-3528	1352	15	,	,	PUNCT
fnp-3528	1352	16	g.	g.	PROPN
fnp-3528	1352	17	;	;	PUNCT
fnp-3528	1352	18	schmitz	schmitz	PROPN
fnp-3528	1352	19	,	,	PUNCT
fnp-3528	1352	20	g.	g.	PROPN
fnp-3528	1352	21	;	;	PUNCT
fnp-3528	1352	22	elias	elias	PROPN
fnp-3528	1352	23	,	,	PUNCT
fnp-3528	1352	24	p.	p.	NOUN
fnp-3528	1352	25	m.	m.	NOUN
fnp-3528	1352	26	;	;	PUNCT
fnp-3528	1352	27	feingold	feingold	PROPN
fnp-3528	1352	28	,	,	PUNCT
fnp-3528	1352	29	k.	k.	PROPN
fnp-3528	1352	30	r.	r.	PROPN
fnp-3528	1352	31	ppar	ppar	PROPN
fnp-3528	1352	32	and	and	CCONJ
fnp-3528	1352	33	lxr	lxr	ADJ
fnp-3528	1352	34	activators	activator	NOUN
fnp-3528	1352	35	regulate	regulate	VERB
fnp-3528	1352	36	abca12	abca12	NOUN
fnp-3528	1352	37	expression	expression	NOUN
fnp-3528	1352	38	in	in	ADP
fnp-3528	1352	39	human	human	ADJ
fnp-3528	1352	40	keratinocytes	keratinocyte	NOUN
fnp-3528	1352	41	.	.	PUNCT
fnp-3528	1353	1	j	j	PROPN
fnp-3528	1353	2	invest	invest	VERB
fnp-3528	1353	3	dermatol	dermatol	NOUN
fnp-3528	1353	4	2008	2008	NUM
fnp-3528	1353	5	,	,	PUNCT
fnp-3528	1353	6	128	128	NUM
fnp-3528	1353	7	,	,	PUNCT
fnp-3528	1353	8	104	104	NUM
fnp-3528	1353	9	-	-	SYM
fnp-3528	1353	10	9	9	NUM
fnp-3528	1353	11	.	.	PUNCT
fnp-3528	1354	1	jiang	jiang	PROPN
fnp-3528	1354	2	,	,	PUNCT
fnp-3528	1354	3	y.	y.	PROPN
fnp-3528	1354	4	j.	j.	PROPN
fnp-3528	1354	5	;	;	PUNCT
fnp-3528	1354	6	uchida	uchida	PROPN
fnp-3528	1354	7	,	,	PUNCT
fnp-3528	1354	8	y.	y.	PROPN
fnp-3528	1354	9	;	;	PUNCT
fnp-3528	1354	10	lu	lu	PROPN
fnp-3528	1354	11	,	,	PUNCT
fnp-3528	1354	12	b.	b.	PROPN
fnp-3528	1354	13	;	;	PUNCT
fnp-3528	1354	14	kim	kim	PROPN
fnp-3528	1354	15	,	,	PUNCT
fnp-3528	1354	16	p.	p.	PROPN
fnp-3528	1354	17	;	;	PUNCT
fnp-3528	1354	18	mao	mao	PROPN
fnp-3528	1354	19	,	,	PUNCT
fnp-3528	1354	20	c.	c.	PROPN
fnp-3528	1354	21	;	;	PUNCT
fnp-3528	1354	22	akiyama	akiyama	PROPN
fnp-3528	1354	23	,	,	PUNCT
fnp-3528	1354	24	m.	m.	NOUN
fnp-3528	1354	25	;	;	PUNCT
fnp-3528	1354	26	elias	elias	PROPN
fnp-3528	1354	27	,	,	PUNCT
fnp-3528	1354	28	p.	p.	NOUN
fnp-3528	1354	29	m.	m.	NOUN
fnp-3528	1354	30	;	;	PUNCT
fnp-3528	1354	31	holleran	holleran	PROPN
fnp-3528	1354	32	,	,	PUNCT
fnp-3528	1354	33	w.	w.	NOUN
fnp-3528	1354	34	m.	m.	NOUN
fnp-3528	1354	35	;	;	PUNCT
fnp-3528	1354	36	grunfeld	grunfeld	NOUN
fnp-3528	1354	37	,	,	PUNCT
fnp-3528	1354	38	c.	c.	PROPN
fnp-3528	1354	39	;	;	PUNCT
fnp-3528	1354	40	feingold	feingold	PROPN
fnp-3528	1354	41	,	,	PUNCT
fnp-3528	1354	42	k.	k.	PROPN
fnp-3528	1354	43	r.	r.	PROPN
fnp-3528	1354	44	ceramide	ceramide	PROPN
fnp-3528	1354	45	stimulates	stimulate	VERB
fnp-3528	1354	46	abca12	abca12	NOUN
fnp-3528	1354	47	expression	expression	NOUN
fnp-3528	1354	48	via	via	ADP
fnp-3528	1354	49	peroxisome	peroxisome	PROPN
fnp-3528	1354	50	proliferator	proliferator	PROPN
fnp-3528	1354	51	-	-	PUNCT
fnp-3528	1354	52	activated	activate	VERB
fnp-3528	1354	53	receptor	receptor	NOUN
fnp-3528	1354	54	{	{	PUNCT
fnp-3528	1354	55	delta	delta	NOUN
fnp-3528	1354	56	}	}	PUNCT
fnp-3528	1354	57	in	in	ADP
fnp-3528	1354	58	human	human	ADJ
fnp-3528	1354	59	keratinocytes	keratinocyte	NOUN
fnp-3528	1354	60	.	.	PUNCT
fnp-3528	1355	1	j	j	PROPN
fnp-3528	1355	2	biol	biol	PROPN
fnp-3528	1355	3	chem	chem	NOUN
fnp-3528	1355	4	2009	2009	NUM
fnp-3528	1355	5	,	,	PUNCT
fnp-3528	1355	6	284	284	NUM
fnp-3528	1355	7	,	,	PUNCT
fnp-3528	1355	8	18942	18942	NUM
fnp-3528	1355	9	-	-	SYM
fnp-3528	1355	10	52	52	NUM
fnp-3528	1355	11	.	.	PUNCT
fnp-3528	1356	1	banno	banno	PROPN
fnp-3528	1356	2	,	,	PUNCT
fnp-3528	1356	3	a.	a.	NOUN
fnp-3528	1356	4	;	;	PUNCT
fnp-3528	1356	5	wang	wang	PROPN
fnp-3528	1356	6	,	,	PUNCT
fnp-3528	1356	7	j.	j.	PROPN
fnp-3528	1356	8	;	;	PUNCT
fnp-3528	1356	9	okada	okada	PROPN
fnp-3528	1356	10	,	,	PUNCT
fnp-3528	1356	11	k.	k.	PROPN
fnp-3528	1356	12	;	;	PUNCT
fnp-3528	1356	13	mori	mori	PROPN
fnp-3528	1356	14	,	,	PUNCT
fnp-3528	1356	15	r.	r.	PROPN
fnp-3528	1356	16	;	;	PUNCT
fnp-3528	1356	17	mijiti	mijiti	PROPN
fnp-3528	1356	18	,	,	PUNCT
fnp-3528	1356	19	m.	m.	NOUN
fnp-3528	1356	20	;	;	PUNCT
fnp-3528	1356	21	nagaoka	nagaoka	NOUN
fnp-3528	1356	22	,	,	PUNCT
fnp-3528	1356	23	s.	s.	PROPN
fnp-3528	1356	24	identification	identification	NOUN
fnp-3528	1356	25	of	of	ADP
fnp-3528	1356	26	a	a	DET
fnp-3528	1356	27	novel	novel	ADJ
fnp-3528	1356	28	cholesterol	cholesterol	NOUN
fnp-3528	1356	29	-	-	PUNCT
fnp-3528	1356	30	lowering	lower	VERB
fnp-3528	1356	31	dipeptide	dipeptide	NOUN
fnp-3528	1356	32	,	,	PUNCT
fnp-3528	1356	33	phenylalanine	phenylalanine	NOUN
fnp-3528	1356	34	-	-	PUNCT
fnp-3528	1356	35	proline	proline	NOUN
fnp-3528	1356	36	(	(	PUNCT
fnp-3528	1356	37	fp	fp	NOUN
fnp-3528	1356	38	)	)	PUNCT
fnp-3528	1356	39	,	,	PUNCT
fnp-3528	1356	40	and	and	CCONJ
fnp-3528	1356	41	its	its	PRON
fnp-3528	1356	42	down	down	ADJ
fnp-3528	1356	43	-	-	PUNCT
fnp-3528	1356	44	regulation	regulation	NOUN
fnp-3528	1356	45	of	of	ADP
fnp-3528	1356	46	intestinal	intestinal	ADJ
fnp-3528	1356	47	abca1	abca1	NOUN
fnp-3528	1356	48	in	in	ADP
fnp-3528	1356	49	hypercholesterolemic	hypercholesterolemic	ADJ
fnp-3528	1356	50	rats	rat	NOUN
fnp-3528	1356	51	and	and	CCONJ
fnp-3528	1356	52	caco-2	caco-2	NUM
fnp-3528	1356	53	cells	cell	NOUN
fnp-3528	1356	54	.	.	PUNCT
fnp-3528	1357	1	sci	sci	PROPN
fnp-3528	1357	2	rep	rep	PROPN
fnp-3528	1357	3	2019	2019	NUM
fnp-3528	1357	4	,	,	PUNCT
fnp-3528	1357	5	9	9	NUM
fnp-3528	1357	6	,	,	PUNCT
fnp-3528	1357	7	19416	19416	NUM
fnp-3528	1357	8	.	.	PUNCT
fnp-3528	1358	1	huang	huang	PROPN
fnp-3528	1358	2	,	,	PUNCT
fnp-3528	1358	3	w.	w.	PROPN
fnp-3528	1358	4	;	;	PUNCT
fnp-3528	1358	5	zhou	zhou	PROPN
fnp-3528	1358	6	,	,	PUNCT
fnp-3528	1358	7	j.	j.	PROPN
fnp-3528	1358	8	;	;	PUNCT
fnp-3528	1358	9	zhang	zhang	PROPN
fnp-3528	1358	10	,	,	PUNCT
fnp-3528	1358	11	g.	g.	PROPN
fnp-3528	1358	12	;	;	PUNCT
fnp-3528	1358	13	zhang	zhang	PROPN
fnp-3528	1358	14	,	,	PUNCT
fnp-3528	1358	15	y.	y.	PROPN
fnp-3528	1358	16	;	;	PUNCT
fnp-3528	1358	17	wang	wang	PROPN
fnp-3528	1358	18	,	,	PUNCT
fnp-3528	1358	19	h.	h.	PROPN
fnp-3528	1358	20	decreased	decrease	VERB
fnp-3528	1358	21	h3k9	h3k9	PROPN
fnp-3528	1358	22	acetylation	acetylation	NOUN
fnp-3528	1358	23	level	level	NOUN
fnp-3528	1358	24	of	of	ADP
fnp-3528	1358	25	lxralpha	lxralpha	NOUN
fnp-3528	1358	26	mediated	mediate	VERB
fnp-3528	1358	27	dexamethasone	dexamethasone	NOUN
fnp-3528	1358	28	-	-	PUNCT
fnp-3528	1358	29	induced	induce	VERB
fnp-3528	1358	30	placental	placental	ADJ
fnp-3528	1358	31	cholesterol	cholesterol	NOUN
fnp-3528	1358	32	transport	transport	NOUN
fnp-3528	1358	33	dysfunction	dysfunction	NOUN
fnp-3528	1358	34	.	.	PUNCT
fnp-3528	1359	1	biochim	biochim	PROPN
fnp-3528	1359	2	biophys	biophy	NOUN
fnp-3528	1359	3	acta	acta	PROPN
fnp-3528	1359	4	mol	mol	ADP
fnp-3528	1359	5	cell	cell	NOUN
fnp-3528	1359	6	biol	biol	NOUN
fnp-3528	1359	7	lipids	lipid	VERB
fnp-3528	1359	8	2019	2019	NUM
fnp-3528	1359	9	,	,	PUNCT
fnp-3528	1359	10	1864	1864	NUM
fnp-3528	1359	11	,	,	PUNCT
fnp-3528	1359	12	158524	158524	NUM
fnp-3528	1359	13	.	.	PUNCT
fnp-3528	1360	1	han	han	PROPN
fnp-3528	1360	2	,	,	PUNCT
fnp-3528	1360	3	q.	q.	PROPN
fnp-3528	1360	4	a.	a.	PROPN
fnp-3528	1360	5	;	;	PUNCT
fnp-3528	1360	6	li	li	PROPN
fnp-3528	1360	7	,	,	PUNCT
fnp-3528	1360	8	k.	k.	PROPN
fnp-3528	1360	9	;	;	PUNCT
fnp-3528	1360	10	dong	dong	PROPN
fnp-3528	1360	11	,	,	PUNCT
fnp-3528	1360	12	x.	x.	PROPN
fnp-3528	1360	13	;	;	PUNCT
fnp-3528	1360	14	luo	luo	PROPN
fnp-3528	1360	15	,	,	PUNCT
fnp-3528	1360	16	y.	y.	PROPN
fnp-3528	1360	17	;	;	PUNCT
fnp-3528	1360	18	zhu	zhu	PROPN
fnp-3528	1360	19	,	,	PUNCT
fnp-3528	1360	20	b.	b.	PROPN
fnp-3528	1360	21	function	function	PROPN
fnp-3528	1360	22	of	of	ADP
fnp-3528	1360	23	thelenota	thelenota	NOUN
fnp-3528	1360	24	ananas	ananas	PROPN
fnp-3528	1360	25	saponin	saponin	PROPN
fnp-3528	1360	26	desulfated	desulfate	VERB
fnp-3528	1360	27	holothurin	holothurin	NOUN
fnp-3528	1360	28	a	a	PRON
fnp-3528	1360	29	in	in	ADP
fnp-3528	1360	30	modulating	modulate	VERB
fnp-3528	1360	31	cholesterol	cholesterol	NOUN
fnp-3528	1360	32	metabolism	metabolism	NOUN
fnp-3528	1360	33	.	.	PUNCT
fnp-3528	1361	1	sci	sci	PROPN
fnp-3528	1361	2	rep	rep	PROPN
fnp-3528	1361	3	2018	2018	NUM
fnp-3528	1361	4	,	,	PUNCT
fnp-3528	1361	5	8	8	NUM
fnp-3528	1361	6	,	,	PUNCT
fnp-3528	1361	7	9506	9506	NUM
fnp-3528	1361	8	.	.	PUNCT
fnp-3528	1362	1	kaplan	kaplan	PROPN
fnp-3528	1362	2	,	,	PUNCT
fnp-3528	1362	3	m.	m.	NOUN
fnp-3528	1362	4	;	;	PUNCT
fnp-3528	1362	5	aviram	aviram	NOUN
fnp-3528	1362	6	,	,	PUNCT
fnp-3528	1362	7	m.	m.	NOUN
fnp-3528	1362	8	;	;	PUNCT
fnp-3528	1362	9	knopf	knopf	PROPN
fnp-3528	1362	10	,	,	PUNCT
fnp-3528	1362	11	c.	c.	PROPN
fnp-3528	1362	12	;	;	PUNCT
fnp-3528	1362	13	keidar	keidar	PROPN
fnp-3528	1362	14	,	,	PUNCT
fnp-3528	1362	15	s.	s.	PROPN
fnp-3528	1362	16	angiotensin	angiotensin	PROPN
fnp-3528	1362	17	ii	ii	PROPN
fnp-3528	1362	18	reduces	reduce	VERB
fnp-3528	1362	19	macrophage	macrophage	ADJ
fnp-3528	1362	20	cholesterol	cholesterol	NOUN
fnp-3528	1362	21	efflux	efflux	NOUN
fnp-3528	1362	22	:	:	PUNCT
fnp-3528	1362	23	a	a	DET
fnp-3528	1362	24	role	role	NOUN
fnp-3528	1362	25	for	for	ADP
fnp-3528	1362	26	the	the	DET
fnp-3528	1362	27	at-1	at-1	PUNCT
fnp-3528	1362	28	receptor	receptor	NOUN
fnp-3528	1362	29	but	but	CCONJ
fnp-3528	1362	30	not	not	PART
fnp-3528	1362	31	for	for	ADP
fnp-3528	1362	32	the	the	DET
fnp-3528	1362	33	abc1	abc1	PROPN
fnp-3528	1362	34	transporter	transporter	NOUN
fnp-3528	1362	35	.	.	PUNCT
fnp-3528	1363	1	biochem	biochem	PROPN
fnp-3528	1363	2	biophys	biophys	PROPN
fnp-3528	1363	3	res	res	PROPN
fnp-3528	1363	4	commun	commun	PROPN
fnp-3528	1363	5	2002	2002	NUM
fnp-3528	1363	6	,	,	PUNCT
fnp-3528	1363	7	290	290	NUM
fnp-3528	1363	8	,	,	PUNCT
fnp-3528	1363	9	1529	1529	NUM
fnp-3528	1363	10	-	-	SYM
fnp-3528	1363	11	34	34	NUM
fnp-3528	1363	12	.	.	PUNCT
fnp-3528	1364	1	yang	yang	PROPN
fnp-3528	1364	2	,	,	PUNCT
fnp-3528	1364	3	y.	y.	PROPN
fnp-3528	1364	4	;	;	PUNCT
fnp-3528	1364	5	yang	yang	PROPN
fnp-3528	1364	6	,	,	PUNCT
fnp-3528	1364	7	q.	q.	PROPN
fnp-3528	1364	8	;	;	PUNCT
fnp-3528	1364	9	yang	yang	PROPN
fnp-3528	1364	10	,	,	PUNCT
fnp-3528	1364	11	j.	j.	PROPN
fnp-3528	1364	12	;	;	PUNCT
fnp-3528	1364	13	ma	ma	PROPN
fnp-3528	1364	14	,	,	PUNCT
fnp-3528	1364	15	y.	y.	PROPN
fnp-3528	1364	16	;	;	PUNCT
fnp-3528	1364	17	ding	ding	NOUN
fnp-3528	1364	18	,	,	PUNCT
fnp-3528	1364	19	g.	g.	PROPN
fnp-3528	1364	20	angiotensin	angiotensin	PROPN
fnp-3528	1364	21	ii	ii	PROPN
fnp-3528	1364	22	induces	induce	VERB
fnp-3528	1364	23	cholesterol	cholesterol	NOUN
fnp-3528	1364	24	accumulation	accumulation	NOUN
fnp-3528	1364	25	and	and	CCONJ
fnp-3528	1364	26	injury	injury	NOUN
fnp-3528	1364	27	in	in	ADP
fnp-3528	1364	28	podocytes	podocyte	NOUN
fnp-3528	1364	29	.	.	PUNCT
fnp-3528	1365	1	sci	sci	PROPN
fnp-3528	1365	2	rep	rep	PROPN
fnp-3528	1365	3	2017	2017	NUM
fnp-3528	1365	4	,	,	PUNCT
fnp-3528	1365	5	7	7	NUM
fnp-3528	1365	6	,	,	PUNCT
fnp-3528	1365	7	10672	10672	NUM
fnp-3528	1365	8	.	.	PUNCT
fnp-3528	1366	1	boulate	boulate	NOUN
fnp-3528	1366	2	,	,	PUNCT
fnp-3528	1366	3	g.	g.	PROPN
fnp-3528	1366	4	;	;	PUNCT
fnp-3528	1366	5	amazit	amazit	PROPN
fnp-3528	1366	6	,	,	PUNCT
fnp-3528	1366	7	l.	l.	PROPN
fnp-3528	1366	8	;	;	PUNCT
fnp-3528	1366	9	naman	naman	PROPN
fnp-3528	1366	10	,	,	PUNCT
fnp-3528	1366	11	a.	a.	PROPN
fnp-3528	1366	12	;	;	PUNCT
fnp-3528	1366	13	seck	seck	PROPN
fnp-3528	1366	14	,	,	PUNCT
fnp-3528	1366	15	a.	a.	NOUN
fnp-3528	1366	16	;	;	PUNCT
fnp-3528	1366	17	paci	paci	PROPN
fnp-3528	1366	18	,	,	PUNCT
fnp-3528	1366	19	a.	a.	NOUN
fnp-3528	1366	20	;	;	PUNCT
fnp-3528	1366	21	lombes	lombe	NOUN
fnp-3528	1366	22	,	,	PUNCT
fnp-3528	1366	23	a.	a.	NOUN
fnp-3528	1366	24	;	;	PUNCT
fnp-3528	1366	25	pussard	pussard	PROPN
fnp-3528	1366	26	,	,	PUNCT
fnp-3528	1366	27	e.	e.	PROPN
fnp-3528	1366	28	;	;	PUNCT
fnp-3528	1366	29	baudin	baudin	VERB
fnp-3528	1366	30	,	,	PUNCT
fnp-3528	1366	31	e.	e.	PROPN
fnp-3528	1366	32	;	;	PUNCT
fnp-3528	1366	33	lombes	lombe	NOUN
fnp-3528	1366	34	,	,	PUNCT
fnp-3528	1366	35	m.	m.	NOUN
fnp-3528	1366	36	;	;	PUNCT
fnp-3528	1366	37	hescot	hescot	PROPN
fnp-3528	1366	38	,	,	PUNCT
fnp-3528	1366	39	s.	s.	PROPN
fnp-3528	1366	40	potentiation	potentiation	NOUN
fnp-3528	1366	41	of	of	ADP
fnp-3528	1366	42	mitotane	mitotane	ADJ
fnp-3528	1366	43	action	action	NOUN
fnp-3528	1366	44	by	by	ADP
fnp-3528	1366	45	rosuvastatin	rosuvastatin	NOUN
fnp-3528	1366	46	:	:	PUNCT
fnp-3528	1366	47	new	new	ADJ
fnp-3528	1366	48	insights	insight	NOUN
fnp-3528	1366	49	for	for	ADP
fnp-3528	1366	50	adrenocortical	adrenocortical	ADJ
fnp-3528	1366	51	carcinoma	carcinoma	NOUN
fnp-3528	1366	52	management	management	NOUN
fnp-3528	1366	53	.	.	PUNCT
fnp-3528	1367	1	int	int	NOUN
fnp-3528	1367	2	j	j	PROPN
fnp-3528	1367	3	oncol	oncol	ADJ
fnp-3528	1367	4	2019	2019	NUM
fnp-3528	1367	5	,	,	PUNCT
fnp-3528	1367	6	54	54	NUM
fnp-3528	1367	7	,	,	PUNCT
fnp-3528	1367	8	2149	2149	NUM
fnp-3528	1367	9	-	-	SYM
fnp-3528	1367	10	56	56	NUM
fnp-3528	1367	11	.	.	PUNCT
fnp-3528	1367	12	wu	wu	PROPN
fnp-3528	1367	13	,	,	PUNCT
fnp-3528	1367	14	x.	x.	PROPN
fnp-3528	1367	15	;	;	PUNCT
fnp-3528	1367	16	li	li	PROPN
fnp-3528	1367	17	,	,	PUNCT
fnp-3528	1367	18	c.	c.	PROPN
fnp-3528	1367	19	;	;	PUNCT
fnp-3528	1367	20	mariyam	mariyam	NOUN
fnp-3528	1367	21	,	,	PUNCT
fnp-3528	1367	22	z.	z.	PROPN
fnp-3528	1367	23	;	;	PUNCT
fnp-3528	1367	24	jiang	jiang	PROPN
fnp-3528	1367	25	,	,	PUNCT
fnp-3528	1367	26	p.	p.	PROPN
fnp-3528	1367	27	;	;	PUNCT
fnp-3528	1367	28	zhou	zhou	PROPN
fnp-3528	1367	29	,	,	PUNCT
fnp-3528	1367	30	m.	m.	NOUN
fnp-3528	1367	31	;	;	PUNCT
fnp-3528	1367	32	zeb	zeb	PROPN
fnp-3528	1367	33	,	,	PUNCT
fnp-3528	1367	34	f.	f.	PROPN
fnp-3528	1367	35	;	;	PUNCT
fnp-3528	1367	36	haq	haq	PROPN
fnp-3528	1367	37	,	,	PUNCT
fnp-3528	1367	38	i.	i.	PROPN
fnp-3528	1367	39	u.	u.	PROPN
fnp-3528	1367	40	;	;	PUNCT
fnp-3528	1367	41	chen	chen	PROPN
fnp-3528	1367	42	,	,	PUNCT
fnp-3528	1367	43	a.	a.	NOUN
fnp-3528	1367	44	;	;	PUNCT
fnp-3528	1367	45	feng	feng	PROPN
fnp-3528	1367	46	,	,	PUNCT
fnp-3528	1367	47	q.	q.	PROPN
fnp-3528	1367	48	acrolein	acrolein	PROPN
fnp-3528	1367	49	-	-	PUNCT
fnp-3528	1367	50	induced	induce	VERB
fnp-3528	1367	51	atherogenesis	atherogenesis	NOUN
fnp-3528	1367	52	by	by	ADP
fnp-3528	1367	53	stimulation	stimulation	NOUN
fnp-3528	1367	54	of	of	ADP
fnp-3528	1367	55	hepatic	hepatic	ADJ
fnp-3528	1367	56	flavin	flavin	NOUN
fnp-3528	1367	57	containing	contain	VERB
fnp-3528	1367	58	monooxygenase	monooxygenase	NOUN
fnp-3528	1367	59	3	3	NUM
fnp-3528	1367	60	and	and	CCONJ
fnp-3528	1367	61	a	a	DET
fnp-3528	1367	62	protection	protection	NOUN
fnp-3528	1367	63	from	from	ADP
fnp-3528	1367	64	hydroxytyrosol	hydroxytyrosol	PROPN
fnp-3528	1367	65	.	.	PUNCT
fnp-3528	1368	1	j	j	PROPN
fnp-3528	1368	2	cell	cell	PROPN
fnp-3528	1368	3	physiol	physiol	PROPN
fnp-3528	1368	4	2018	2018	NUM
fnp-3528	1368	5	,	,	PUNCT
fnp-3528	1368	6	234	234	NUM
fnp-3528	1368	7	,	,	PUNCT
fnp-3528	1368	8	475	475	NUM
fnp-3528	1368	9	-	-	SYM
fnp-3528	1368	10	85	85	NUM
fnp-3528	1368	11	.	.	PUNCT
fnp-3528	1369	1	samardzija	samardzija	NOUN
fnp-3528	1369	2	,	,	PUNCT
fnp-3528	1369	3	d.	d.	PROPN
fnp-3528	1369	4	;	;	PUNCT
fnp-3528	1369	5	pogrmic	pogrmic	ADJ
fnp-3528	1369	6	-	-	PUNCT
fnp-3528	1369	7	majkic	majkic	PROPN
fnp-3528	1369	8	,	,	PUNCT
fnp-3528	1369	9	k.	k.	PROPN
fnp-3528	1369	10	;	;	PUNCT
fnp-3528	1369	11	fa	fa	PROPN
fnp-3528	1369	12	,	,	PUNCT
fnp-3528	1369	13	s.	s.	PROPN
fnp-3528	1369	14	;	;	PUNCT
fnp-3528	1369	15	stanic	stanic	PROPN
fnp-3528	1369	16	,	,	PUNCT
fnp-3528	1369	17	b.	b.	PROPN
fnp-3528	1369	18	;	;	PUNCT
fnp-3528	1369	19	jasnic	jasnic	PROPN
fnp-3528	1369	20	,	,	PUNCT
fnp-3528	1369	21	j.	j.	PROPN
fnp-3528	1369	22	;	;	PUNCT
fnp-3528	1369	23	andric	andric	ADJ
fnp-3528	1369	24	,	,	PUNCT
fnp-3528	1369	25	n.	n.	NOUN
fnp-3528	1369	26	bisphenol	bisphenol	NOUN
fnp-3528	1369	27	a	a	DET
fnp-3528	1369	28	decreases	decrease	NOUN
fnp-3528	1369	29	progesterone	progesterone	NOUN
fnp-3528	1369	30	synthesis	synthesis	NOUN
fnp-3528	1369	31	by	by	ADP
fnp-3528	1369	32	disrupting	disrupt	VERB
fnp-3528	1369	33	cholesterol	cholesterol	NOUN
fnp-3528	1369	34	homeostasis	homeostasis	NOUN
fnp-3528	1369	35	in	in	ADP
fnp-3528	1369	36	rat	rat	NOUN
fnp-3528	1369	37	granulosa	granulosa	NOUN
fnp-3528	1369	38	cells	cell	NOUN
fnp-3528	1369	39	.	.	PUNCT
fnp-3528	1370	1	mol	mol	ADP
fnp-3528	1370	2	cell	cell	NOUN
fnp-3528	1370	3	endocrinol	endocrinol	NOUN
fnp-3528	1370	4	2018	2018	NUM
fnp-3528	1370	5	,	,	PUNCT
fnp-3528	1370	6	461	461	NUM
fnp-3528	1370	7	,	,	PUNCT
fnp-3528	1370	8	55	55	NUM
fnp-3528	1370	9	-	-	SYM
fnp-3528	1370	10	63	63	NUM
fnp-3528	1370	11	.	.	PUNCT
fnp-3528	1370	12	kant	kant	PROPN
fnp-3528	1370	13	,	,	PUNCT
fnp-3528	1370	14	r.	r.	PROPN
fnp-3528	1370	15	;	;	PUNCT
fnp-3528	1370	16	lu	lu	PROPN
fnp-3528	1370	17	,	,	PUNCT
fnp-3528	1370	18	c.	c.	PROPN
fnp-3528	1370	19	k.	k.	PROPN
fnp-3528	1370	20	;	;	PUNCT
fnp-3528	1370	21	nguyen	nguyen	PROPN
fnp-3528	1370	22	,	,	PUNCT
fnp-3528	1370	23	h.	h.	PROPN
fnp-3528	1370	24	m.	m.	PROPN
fnp-3528	1370	25	;	;	PUNCT
fnp-3528	1370	26	hsiao	hsiao	PROPN
fnp-3528	1370	27	,	,	PUNCT
fnp-3528	1370	28	h.	h.	PROPN
fnp-3528	1370	29	h.	h.	PROPN
fnp-3528	1370	30	;	;	PUNCT
fnp-3528	1370	31	chen	chen	PROPN
fnp-3528	1370	32	,	,	PUNCT
fnp-3528	1370	33	c.	c.	PROPN
fnp-3528	1370	34	j.	j.	PROPN
fnp-3528	1370	35	;	;	PUNCT
fnp-3528	1370	36	hsiao	hsiao	PROPN
fnp-3528	1370	37	,	,	PUNCT
fnp-3528	1370	38	h.	h.	PROPN
fnp-3528	1370	39	p.	p.	PROPN
fnp-3528	1370	40	;	;	PUNCT
fnp-3528	1370	41	lin	lin	PROPN
fnp-3528	1370	42	,	,	PUNCT
fnp-3528	1370	43	k.	k.	PROPN
fnp-3528	1370	44	j.	j.	PROPN
fnp-3528	1370	45	;	;	PUNCT
fnp-3528	1370	46	fang	fang	PROPN
fnp-3528	1370	47	,	,	PUNCT
fnp-3528	1370	48	c.	c.	PROPN
fnp-3528	1370	49	c.	c.	PROPN
fnp-3528	1370	50	;	;	PUNCT
fnp-3528	1370	51	yen	yen	NOUN
fnp-3528	1370	52	,	,	PUNCT
fnp-3528	1370	53	c.	c.	PROPN
fnp-3528	1370	54	h.	h.	PROPN
fnp-3528	1370	55	1,2,3,4,6	1,2,3,4,6	NUM
fnp-3528	1370	56	penta	penta	PROPN
fnp-3528	1370	57	-	-	PUNCT
fnp-3528	1370	58	o	o	NOUN
fnp-3528	1370	59	-	-	ADJ
fnp-3528	1370	60	galloyl	galloyl	ADJ
fnp-3528	1370	61	-	-	PUNCT
fnp-3528	1370	62	beta	beta	NOUN
fnp-3528	1370	63	-	-	PUNCT
fnp-3528	1370	64	d	d	NOUN
fnp-3528	1370	65	-	-	PUNCT
fnp-3528	1370	66	glucose	glucose	NOUN
fnp-3528	1370	67	ameliorates	ameliorate	VERB
fnp-3528	1370	68	high	high	ADJ
fnp-3528	1370	69	-	-	PUNCT
fnp-3528	1370	70	fat	fat	NOUN
fnp-3528	1370	71	diet	diet	NOUN
fnp-3528	1370	72	-	-	PUNCT
fnp-3528	1370	73	induced	induce	VERB
fnp-3528	1370	74	nonalcoholic	nonalcoholic	NOUN
fnp-3528	1370	75	fatty	fatty	NOUN
fnp-3528	1370	76	liver	liver	NOUN
fnp-3528	1370	77	disease	disease	NOUN
fnp-3528	1370	78	and	and	CCONJ
fnp-3528	1370	79	maintains	maintain	VERB
fnp-3528	1370	80	the	the	DET
fnp-3528	1370	81	expression	expression	NOUN
fnp-3528	1370	82	of	of	ADP
fnp-3528	1370	83	genes	gene	NOUN
fnp-3528	1370	84	involved	involve	VERB
fnp-3528	1370	85	in	in	ADP
fnp-3528	1370	86	lipid	lipid	ADJ
fnp-3528	1370	87	homeostasis	homeostasis	NOUN
fnp-3528	1370	88	in	in	ADP
fnp-3528	1370	89	mice	mouse	NOUN
fnp-3528	1370	90	.	.	PUNCT
fnp-3528	1370	91	biomed	biome	VERB
fnp-3528	1370	92	pharmacother	pharmacother	ADJ
fnp-3528	1370	93	2020	2020	NUM
fnp-3528	1370	94	,	,	PUNCT
fnp-3528	1370	95	129	129	NUM
fnp-3528	1370	96	,	,	PUNCT
fnp-3528	1370	97	110348	110348	NUM
fnp-3528	1370	98	.	.	PUNCT
fnp-3528	1371	1	zhang	zhang	PROPN
fnp-3528	1371	2	,	,	PUNCT
fnp-3528	1371	3	x.	x.	PROPN
fnp-3528	1371	4	;	;	PUNCT
fnp-3528	1371	5	qin	qin	PROPN
fnp-3528	1371	6	,	,	PUNCT
fnp-3528	1371	7	y.	y.	PROPN
fnp-3528	1371	8	;	;	PUNCT
fnp-3528	1371	9	wan	wan	PROPN
fnp-3528	1371	10	,	,	PUNCT
fnp-3528	1371	11	x.	x.	PROPN
fnp-3528	1371	12	;	;	PUNCT
fnp-3528	1371	13	liu	liu	PROPN
fnp-3528	1371	14	,	,	PUNCT
fnp-3528	1371	15	h.	h.	PROPN
fnp-3528	1371	16	;	;	PUNCT
fnp-3528	1371	17	iv	iv	X
fnp-3528	1371	18	,	,	PUNCT
fnp-3528	1371	19	c.	c.	PROPN
fnp-3528	1371	20	;	;	PUNCT
fnp-3528	1371	21	ruan	ruan	PROPN
fnp-3528	1371	22	,	,	PUNCT
fnp-3528	1371	23	w.	w.	PROPN
fnp-3528	1371	24	;	;	PUNCT
fnp-3528	1371	25	lu	lu	PROPN
fnp-3528	1371	26	,	,	PUNCT
fnp-3528	1371	27	l.	l.	PROPN
fnp-3528	1371	28	;	;	PUNCT
fnp-3528	1371	29	he	he	PRON
fnp-3528	1371	30	,	,	PUNCT
fnp-3528	1371	31	l.	l.	PROPN
fnp-3528	1371	32	;	;	PUNCT
fnp-3528	1371	33	guo	guo	PROPN
fnp-3528	1371	34	,	,	PUNCT
fnp-3528	1371	35	x.	x.	PROPN
fnp-3528	1371	36	hydroxytyrosol	hydroxytyrosol	PROPN
fnp-3528	1371	37	plays	play	VERB
fnp-3528	1371	38	antiatherosclerotic	antiatherosclerotic	ADJ
fnp-3528	1371	39	effects	effect	NOUN
fnp-3528	1371	40	through	through	ADP
fnp-3528	1371	41	regulating	regulate	VERB
fnp-3528	1371	42	lipid	lipid	NOUN
fnp-3528	1371	43	metabolism	metabolism	NOUN
fnp-3528	1371	44	via	via	ADP
fnp-3528	1371	45	inhibiting	inhibit	VERB
fnp-3528	1371	46	the	the	DET
fnp-3528	1371	47	p38	p38	NOUN
fnp-3528	1371	48	signal	signal	NOUN
fnp-3528	1371	49	pathway	pathway	NOUN
fnp-3528	1371	50	.	.	PUNCT
fnp-3528	1372	1	biomed	biome	VERB
fnp-3528	1372	2	res	re	NOUN
fnp-3528	1372	3	int	int	NOUN
fnp-3528	1372	4	2020	2020	NUM
fnp-3528	1372	5	,	,	PUNCT
fnp-3528	1372	6	2020	2020	NUM
fnp-3528	1372	7	,	,	PUNCT
fnp-3528	1372	8	5036572	5036572	NUM
fnp-3528	1372	9	.	.	PUNCT
fnp-3528	1373	1	li	li	PROPN
fnp-3528	1373	2	,	,	PUNCT
fnp-3528	1373	3	y.	y.	PROPN
fnp-3528	1373	4	;	;	PUNCT
fnp-3528	1373	5	wu	wu	PROPN
fnp-3528	1373	6	,	,	PUNCT
fnp-3528	1373	7	s.	s.	PROPN
fnp-3528	1373	8	epigallocatechin	epigallocatechin	PROPN
fnp-3528	1373	9	gallate	gallate	PROPN
fnp-3528	1373	10	suppresses	suppress	VERB
fnp-3528	1373	11	hepatic	hepatic	ADJ
fnp-3528	1373	12	cholesterol	cholesterol	NOUN
fnp-3528	1373	13	synthesis	synthesis	NOUN
fnp-3528	1373	14	by	by	ADP
fnp-3528	1373	15	targeting	target	VERB
fnp-3528	1373	16	srebp-2	srebp-2	PROPN
fnp-3528	1373	17	through	through	ADP
fnp-3528	1373	18	sirt1	sirt1	NOUN
fnp-3528	1373	19	/	/	SYM
fnp-3528	1373	20	foxo1	foxo1	NOUN
fnp-3528	1373	21	signaling	signal	VERB
fnp-3528	1373	22	pathway	pathway	NOUN
fnp-3528	1373	23	.	.	PUNCT
fnp-3528	1374	1	mol	mol	ADP
fnp-3528	1374	2	cell	cell	NOUN
fnp-3528	1374	3	biochem	biochem	NOUN
fnp-3528	1374	4	2018	2018	NUM
fnp-3528	1374	5	,	,	PUNCT
fnp-3528	1374	6	448	448	NUM
fnp-3528	1374	7	,	,	PUNCT
fnp-3528	1374	8	175	175	NUM
fnp-3528	1374	9	-	-	SYM
fnp-3528	1374	10	85	85	NUM
fnp-3528	1374	11	.	.	PUNCT
fnp-3528	1375	1	chen	chen	PROPN
fnp-3528	1375	2	,	,	PUNCT
fnp-3528	1375	3	j.	j.	PROPN
fnp-3528	1375	4	h.	h.	PROPN
fnp-3528	1375	5	;	;	PUNCT
fnp-3528	1375	6	zheng	zheng	PROPN
fnp-3528	1375	7	,	,	PUNCT
fnp-3528	1375	8	y.	y.	PROPN
fnp-3528	1375	9	l.	l.	PROPN
fnp-3528	1375	10	;	;	PUNCT
fnp-3528	1375	11	xu	xu	PROPN
fnp-3528	1375	12	,	,	PUNCT
fnp-3528	1375	13	c.	c.	PROPN
fnp-3528	1375	14	q.	q.	PROPN
fnp-3528	1375	15	;	;	PUNCT
fnp-3528	1375	16	gu	gu	PROPN
fnp-3528	1375	17	,	,	PUNCT
fnp-3528	1375	18	l.	l.	PROPN
fnp-3528	1375	19	z.	z.	PROPN
fnp-3528	1375	20	;	;	PUNCT
fnp-3528	1375	21	ding	ding	PROPN
fnp-3528	1375	22	,	,	PUNCT
fnp-3528	1375	23	z.	z.	PROPN
fnp-3528	1375	24	l.	l.	PROPN
fnp-3528	1375	25	;	;	PUNCT
fnp-3528	1375	26	qin	qin	PROPN
fnp-3528	1375	27	,	,	PUNCT
fnp-3528	1375	28	l.	l.	PROPN
fnp-3528	1375	29	;	;	PUNCT
fnp-3528	1375	30	wang	wang	PROPN
fnp-3528	1375	31	,	,	PUNCT
fnp-3528	1375	32	y.	y.	PROPN
fnp-3528	1375	33	;	;	PUNCT
fnp-3528	1375	34	fu	fu	PROPN
fnp-3528	1375	35	,	,	PUNCT
fnp-3528	1375	36	r.	r.	PROPN
fnp-3528	1375	37	;	;	PUNCT
fnp-3528	1375	38	wan	wan	PROPN
fnp-3528	1375	39	,	,	PUNCT
fnp-3528	1375	40	y.	y.	PROPN
fnp-3528	1375	41	f.	f.	PROPN
fnp-3528	1375	42	;	;	PUNCT
fnp-3528	1375	43	hu	hu	PROPN
fnp-3528	1375	44	,	,	PUNCT
fnp-3528	1375	45	c.	c.	PROPN
fnp-3528	1375	46	p.	p.	NOUN
fnp-3528	1375	47	valproic	valproic	PROPN
fnp-3528	1375	48	acid	acid	NOUN
fnp-3528	1375	49	(	(	PUNCT
fnp-3528	1375	50	vpa	vpa	PROPN
fnp-3528	1375	51	)	)	PUNCT
fnp-3528	1375	52	enhances	enhance	VERB
fnp-3528	1375	53	cisplatin	cisplatin	NOUN
fnp-3528	1375	54	sensitivity	sensitivity	NOUN
fnp-3528	1375	55	of	of	ADP
fnp-3528	1375	56	non	non	ADJ
fnp-3528	1375	57	-	-	ADJ
fnp-3528	1375	58	small	small	ADJ
fnp-3528	1375	59	cell	cell	NOUN
fnp-3528	1375	60	lung	lung	NOUN
fnp-3528	1375	61	cancer	cancer	NOUN
fnp-3528	1375	62	cells	cell	NOUN
fnp-3528	1375	63	via	via	ADP
fnp-3528	1375	64	hdac2	hdac2	NOUN
fnp-3528	1375	65	mediated	mediate	VERB
fnp-3528	1375	66	down	down	ADP
fnp-3528	1375	67	regulation	regulation	NOUN
fnp-3528	1375	68	of	of	ADP
fnp-3528	1375	69	abca1	abca1	NOUN
fnp-3528	1375	70	.	.	PUNCT
fnp-3528	1376	1	biol	biol	PROPN
fnp-3528	1376	2	chem	chem	NOUN
fnp-3528	1376	3	2017	2017	NUM
fnp-3528	1376	4	,	,	PUNCT
fnp-3528	1376	5	398	398	NUM
fnp-3528	1376	6	,	,	PUNCT
fnp-3528	1376	7	785	785	NUM
fnp-3528	1376	8	-	-	SYM
fnp-3528	1376	9	92	92	NUM
fnp-3528	1376	10	.	.	PUNCT
fnp-3528	1377	1	koga	koga	NOUN
fnp-3528	1377	2	,	,	PUNCT
fnp-3528	1377	3	m.	m.	NOUN
fnp-3528	1377	4	;	;	PUNCT
fnp-3528	1377	5	kanaoka	kanaoka	NOUN
fnp-3528	1377	6	,	,	PUNCT
fnp-3528	1377	7	y.	y.	PROPN
fnp-3528	1377	8	;	;	PUNCT
fnp-3528	1377	9	okamoto	okamoto	PROPN
fnp-3528	1377	10	,	,	PUNCT
fnp-3528	1377	11	m.	m.	NOUN
fnp-3528	1377	12	;	;	PUNCT
fnp-3528	1377	13	nakao	nakao	PROPN
fnp-3528	1377	14	,	,	PUNCT
fnp-3528	1377	15	y.	y.	PROPN
fnp-3528	1377	16	;	;	PUNCT
fnp-3528	1377	17	inada	inada	PROPN
fnp-3528	1377	18	,	,	PUNCT
fnp-3528	1377	19	k.	k.	PROPN
fnp-3528	1377	20	;	;	PUNCT
fnp-3528	1377	21	takayama	takayama	PROPN
fnp-3528	1377	22	,	,	PUNCT
fnp-3528	1377	23	s.	s.	PROPN
fnp-3528	1377	24	;	;	PUNCT
fnp-3528	1377	25	kataoka	kataoka	PROPN
fnp-3528	1377	26	,	,	PUNCT
fnp-3528	1377	27	y.	y.	PROPN
fnp-3528	1377	28	;	;	PUNCT
fnp-3528	1377	29	yamauchi	yamauchi	PROPN
fnp-3528	1377	30	,	,	PUNCT
fnp-3528	1377	31	a.	a.	NOUN
fnp-3528	1377	32	varenicline	varenicline	PROPN
fnp-3528	1377	33	aggravates	aggravate	VERB
fnp-3528	1377	34	atherosclerotic	atherosclerotic	ADJ
fnp-3528	1377	35	plaque	plaque	NOUN
fnp-3528	1377	36	formation	formation	NOUN
fnp-3528	1377	37	in	in	ADP
fnp-3528	1377	38	nicotine	nicotine	NOUN
fnp-3528	1377	39	-	-	PUNCT
fnp-3528	1377	40	pretreated	pretreate	VERB
fnp-3528	1377	41	apoe	apoe	ADJ
fnp-3528	1377	42	knockout	knockout	NOUN
fnp-3528	1377	43	mice	mouse	NOUN
fnp-3528	1377	44	due	due	ADJ
fnp-3528	1377	45	to	to	ADP
fnp-3528	1377	46	enhanced	enhanced	ADJ
fnp-3528	1377	47	oxldl	oxldl	NOUN
fnp-3528	1377	48	uptake	uptake	NOUN
fnp-3528	1377	49	by	by	ADP
fnp-3528	1377	50	macrophages	macrophage	NOUN
fnp-3528	1377	51	through	through	ADP
fnp-3528	1377	52	downregulation	downregulation	NOUN
fnp-3528	1377	53	of	of	ADP
fnp-3528	1377	54	abca1	abca1	NOUN
fnp-3528	1377	55	and	and	CCONJ
fnp-3528	1377	56	abcg1	abcg1	ADP
fnp-3528	1377	57	expression	expression	NOUN
fnp-3528	1377	58	.	.	PUNCT
fnp-3528	1378	1	j	j	PROPN
fnp-3528	1378	2	pharmacol	pharmacol	PROPN
fnp-3528	1378	3	sci	sci	PROPN
fnp-3528	1378	4	2020	2020	NUM
fnp-3528	1378	5	,	,	PUNCT
fnp-3528	1378	6	142	142	NUM
fnp-3528	1378	7	,	,	PUNCT
fnp-3528	1378	8	9	9	NUM
fnp-3528	1378	9	-	-	SYM
fnp-3528	1378	10	15	15	NUM
fnp-3528	1378	11	.	.	PUNCT
fnp-3528	1379	1	aung	aung	PROPN
fnp-3528	1379	2	,	,	PUNCT
fnp-3528	1379	3	t.	t.	PROPN
fnp-3528	1379	4	;	;	PUNCT
fnp-3528	1379	5	chapuy	chapuy	NOUN
fnp-3528	1379	6	,	,	PUNCT
fnp-3528	1379	7	b.	b.	PROPN
fnp-3528	1379	8	;	;	PUNCT
fnp-3528	1379	9	vogel	vogel	PROPN
fnp-3528	1379	10	,	,	PUNCT
fnp-3528	1379	11	d.	d.	PROPN
fnp-3528	1379	12	;	;	PUNCT
fnp-3528	1379	13	wenzel	wenzel	PROPN
fnp-3528	1379	14	,	,	PUNCT
fnp-3528	1379	15	d.	d.	PROPN
fnp-3528	1379	16	;	;	PUNCT
fnp-3528	1379	17	oppermann	oppermann	PROPN
fnp-3528	1379	18	,	,	PUNCT
fnp-3528	1379	19	m.	m.	NOUN
fnp-3528	1379	20	;	;	PUNCT
fnp-3528	1379	21	lahmann	lahmann	PROPN
fnp-3528	1379	22	,	,	PUNCT
fnp-3528	1379	23	m.	m.	NOUN
fnp-3528	1379	24	;	;	PUNCT
fnp-3528	1379	25	weinhage	weinhage	NOUN
fnp-3528	1379	26	,	,	PUNCT
fnp-3528	1379	27	t.	t.	PROPN
fnp-3528	1379	28	;	;	PUNCT
fnp-3528	1379	29	menck	menck	NUM
fnp-3528	1379	30	,	,	PUNCT
fnp-3528	1379	31	k.	k.	PROPN
fnp-3528	1379	32	;	;	PUNCT
fnp-3528	1379	33	hupfeld	hupfeld	ADJ
fnp-3528	1379	34	,	,	PUNCT
fnp-3528	1379	35	t.	t.	PROPN
fnp-3528	1379	36	;	;	PUNCT
fnp-3528	1379	37	koch	koch	PROPN
fnp-3528	1379	38	,	,	PUNCT
fnp-3528	1379	39	r.	r.	PROPN
fnp-3528	1379	40	;	;	PUNCT
fnp-3528	1379	41	trumper	trumper	PROPN
fnp-3528	1379	42	,	,	PUNCT
fnp-3528	1379	43	l.	l.	PROPN
fnp-3528	1379	44	;	;	PUNCT
fnp-3528	1379	45	wulf	wulf	PROPN
fnp-3528	1379	46	,	,	PUNCT
fnp-3528	1379	47	g.	g.	PROPN
fnp-3528	1379	48	g.	g.	PROPN
fnp-3528	1379	49	exosomal	exosomal	ADJ
fnp-3528	1379	50	evasion	evasion	NOUN
fnp-3528	1379	51	of	of	ADP
fnp-3528	1379	52	humoral	humoral	ADJ
fnp-3528	1379	53	immunotherapy	immunotherapy	NOUN
fnp-3528	1379	54	in	in	ADP
fnp-3528	1379	55	aggressive	aggressive	ADJ
fnp-3528	1379	56	b	b	NOUN
fnp-3528	1379	57	-	-	PUNCT
fnp-3528	1379	58	cell	cell	NOUN
fnp-3528	1379	59	lymphoma	lymphoma	NOUN
fnp-3528	1379	60	modulated	modulate	VERB
fnp-3528	1379	61	by	by	ADP
fnp-3528	1379	62	atp	atp	NOUN
fnp-3528	1379	63	-	-	PUNCT
fnp-3528	1379	64	binding	bind	VERB
fnp-3528	1379	65	cassette	cassette	NOUN
fnp-3528	1379	66	transporter	transporter	NOUN
fnp-3528	1379	67	a3	a3	NOUN
fnp-3528	1379	68	.	.	PUNCT
fnp-3528	1380	1	proc	proc	PROPN
fnp-3528	1380	2	natl	natl	PROPN
fnp-3528	1380	3	acad	acad	PROPN
fnp-3528	1380	4	sci	sci	PROPN
fnp-3528	1380	5	u	u	PROPN
fnp-3528	1380	6	s	s	PROPN
fnp-3528	1380	7	a	a	DET
fnp-3528	1380	8	2011	2011	NUM
fnp-3528	1380	9	,	,	PUNCT
fnp-3528	1380	10	108	108	NUM
fnp-3528	1380	11	,	,	PUNCT
fnp-3528	1380	12	15336	15336	NUM
fnp-3528	1380	13	-	-	SYM
fnp-3528	1380	14	41	41	NUM
fnp-3528	1380	15	.	.	PUNCT
fnp-3528	1381	1	song	song	PROPN
fnp-3528	1381	2	,	,	PUNCT
fnp-3528	1381	3	j.	j.	PROPN
fnp-3528	1381	4	h.	h.	PROPN
fnp-3528	1381	5	;	;	PUNCT
fnp-3528	1381	6	kim	kim	PROPN
fnp-3528	1381	7	,	,	PUNCT
fnp-3528	1381	8	s.	s.	PROPN
fnp-3528	1381	9	h.	h.	PROPN
fnp-3528	1381	10	;	;	PUNCT
fnp-3528	1381	11	kim	kim	PROPN
fnp-3528	1381	12	,	,	PUNCT
fnp-3528	1381	13	h.	h.	PROPN
fnp-3528	1381	14	j.	j.	PROPN
fnp-3528	1381	15	;	;	PUNCT
fnp-3528	1381	16	hwang	hwang	PROPN
fnp-3528	1381	17	,	,	PUNCT
fnp-3528	1381	18	s.	s.	PROPN
fnp-3528	1381	19	y.	y.	PROPN
fnp-3528	1381	20	;	;	PUNCT
fnp-3528	1381	21	kim	kim	PROPN
fnp-3528	1381	22	,	,	PUNCT
fnp-3528	1381	23	t.	t.	PROPN
fnp-3528	1381	24	s.	s.	PROPN
fnp-3528	1381	25	alleviation	alleviation	PROPN
fnp-3528	1381	26	of	of	ADP
fnp-3528	1381	27	the	the	DET
fnp-3528	1381	28	drug	drug	NOUN
fnp-3528	1381	29	-	-	PUNCT
fnp-3528	1381	30	resistant	resistant	ADJ
fnp-3528	1381	31	phenotype	phenotype	NOUN
fnp-3528	1381	32	in	in	ADP
fnp-3528	1381	33	idarubicin	idarubicin	NOUN
fnp-3528	1381	34	and	and	CCONJ
fnp-3528	1381	35	cytosine	cytosine	VERB
fnp-3528	1381	36	arabinoside	arabinoside	ADJ
fnp-3528	1381	37	double	double	ADJ
fnp-3528	1381	38	-	-	PUNCT
fnp-3528	1381	39	resistant	resistant	ADJ
fnp-3528	1381	40	acute	acute	NOUN
fnp-3528	1381	41	myeloid	myeloid	NOUN
fnp-3528	1381	42	leukemia	leukemia	NOUN
fnp-3528	1381	43	cells	cell	NOUN
fnp-3528	1381	44	by	by	ADP
fnp-3528	1381	45	indomethacin	indomethacin	PROPN
fnp-3528	1381	46	.	.	PUNCT
fnp-3528	1382	1	int	int	PROPN
fnp-3528	1382	2	j	j	PROPN
fnp-3528	1382	3	oncol	oncol	ADJ
fnp-3528	1382	4	2008	2008	NUM
fnp-3528	1382	5	,	,	PUNCT
fnp-3528	1382	6	32	32	NUM
fnp-3528	1382	7	,	,	PUNCT
fnp-3528	1382	8	931	931	NUM
fnp-3528	1382	9	-	-	SYM
fnp-3528	1382	10	6	6	NUM
fnp-3528	1382	11	.	.	PUNCT
fnp-3528	1383	1	dai	dai	PROPN
fnp-3528	1383	2	,	,	PUNCT
fnp-3528	1383	3	w.	w.	PROPN
fnp-3528	1383	4	;	;	PUNCT
fnp-3528	1383	5	wang	wang	PROPN
fnp-3528	1383	6	,	,	PUNCT
fnp-3528	1383	7	f.	f.	PROPN
fnp-3528	1383	8	;	;	PUNCT
fnp-3528	1383	9	he	he	PRON
fnp-3528	1383	10	,	,	PUNCT
fnp-3528	1383	11	l.	l.	PROPN
fnp-3528	1383	12	;	;	PUNCT
fnp-3528	1383	13	lin	lin	PROPN
fnp-3528	1383	14	,	,	PUNCT
fnp-3528	1383	15	c.	c.	PROPN
fnp-3528	1383	16	;	;	PUNCT
fnp-3528	1383	17	wu	wu	PROPN
fnp-3528	1383	18	,	,	PUNCT
fnp-3528	1383	19	s.	s.	PROPN
fnp-3528	1383	20	;	;	PUNCT
fnp-3528	1383	21	chen	chen	PROPN
fnp-3528	1383	22	,	,	PUNCT
fnp-3528	1383	23	p.	p.	PROPN
fnp-3528	1383	24	;	;	PUNCT
fnp-3528	1383	25	zhang	zhang	PROPN
fnp-3528	1383	26	,	,	PUNCT
fnp-3528	1383	27	y.	y.	PROPN
fnp-3528	1383	28	;	;	PUNCT
fnp-3528	1383	29	shen	shen	PROPN
fnp-3528	1383	30	,	,	PUNCT
fnp-3528	1383	31	m.	m.	NOUN
fnp-3528	1383	32	;	;	PUNCT
fnp-3528	1383	33	wu	wu	PROPN
fnp-3528	1383	34	,	,	PUNCT
fnp-3528	1383	35	d.	d.	PROPN
fnp-3528	1383	36	;	;	PUNCT
fnp-3528	1383	37	wang	wang	PROPN
fnp-3528	1383	38	,	,	PUNCT
fnp-3528	1383	39	c.	c.	PROPN
fnp-3528	1383	40	;	;	PUNCT
fnp-3528	1383	41	lu	lu	PROPN
fnp-3528	1383	42	,	,	PUNCT
fnp-3528	1383	43	j.	j.	PROPN
fnp-3528	1383	44	;	;	PUNCT
fnp-3528	1383	45	zhou	zhou	PROPN
fnp-3528	1383	46	,	,	PUNCT
fnp-3528	1383	47	y.	y.	PROPN
fnp-3528	1383	48	;	;	PUNCT
fnp-3528	1383	49	xu	xu	PROPN
fnp-3528	1383	50	,	,	PUNCT
fnp-3528	1383	51	x.	x.	PROPN
fnp-3528	1383	52	;	;	PUNCT
fnp-3528	1383	53	xu	xu	PROPN
fnp-3528	1383	54	,	,	PUNCT
fnp-3528	1383	55	l.	l.	PROPN
fnp-3528	1383	56	;	;	PUNCT
fnp-3528	1383	57	guo	guo	PROPN
fnp-3528	1383	58	,	,	PUNCT
fnp-3528	1383	59	c.	c.	PROPN
fnp-3528	1383	60	genistein	genistein	PROPN
fnp-3528	1383	61	inhibits	inhibit	VERB
fnp-3528	1383	62	hepatocellular	hepatocellular	ADJ
fnp-3528	1383	63	carcinoma	carcinoma	NOUN
fnp-3528	1383	64	cell	cell	NOUN
fnp-3528	1383	65	migration	migration	NOUN
fnp-3528	1383	66	by	by	ADP
fnp-3528	1383	67	reversing	reverse	VERB
fnp-3528	1383	68	the	the	DET
fnp-3528	1383	69	epithelial	epithelial	ADJ
fnp-3528	1383	70	-	-	PUNCT
fnp-3528	1383	71	mesenchymal	mesenchymal	NOUN
fnp-3528	1383	72	transition	transition	NOUN
fnp-3528	1383	73	:	:	PUNCT
fnp-3528	1383	74	partial	partial	ADJ
fnp-3528	1383	75	mediation	mediation	NOUN
fnp-3528	1383	76	by	by	ADP
fnp-3528	1383	77	the	the	DET
fnp-3528	1383	78	transcription	transcription	NOUN
fnp-3528	1383	79	factor	factor	NOUN
fnp-3528	1383	80	nfat1	nfat1	PROPN
fnp-3528	1383	81	.	.	PUNCT
fnp-3528	1384	1	mol	mol	ADP
fnp-3528	1384	2	carcinog	carcinog	PROPN
fnp-3528	1384	3	2015	2015	NUM
fnp-3528	1384	4	,	,	PUNCT
fnp-3528	1384	5	54	54	NUM
fnp-3528	1384	6	,	,	PUNCT
fnp-3528	1384	7	301	301	NUM
fnp-3528	1384	8	-	-	SYM
fnp-3528	1384	9	11	11	NUM
fnp-3528	1384	10	.	.	PUNCT
fnp-3528	1385	1	long	long	ADV
fnp-3528	1385	2	,	,	PUNCT
fnp-3528	1385	3	y.	y.	PROPN
fnp-3528	1385	4	;	;	PUNCT
fnp-3528	1385	5	wang	wang	PROPN
fnp-3528	1385	6	,	,	PUNCT
fnp-3528	1385	7	g.	g.	PROPN
fnp-3528	1385	8	;	;	PUNCT
fnp-3528	1385	9	li	li	PROPN
fnp-3528	1385	10	,	,	PUNCT
fnp-3528	1385	11	k.	k.	PROPN
fnp-3528	1385	12	;	;	PUNCT
fnp-3528	1385	13	zhang	zhang	PROPN
fnp-3528	1385	14	,	,	PUNCT
fnp-3528	1385	15	z.	z.	PROPN
fnp-3528	1385	16	;	;	PUNCT
fnp-3528	1385	17	zhang	zhang	PROPN
fnp-3528	1385	18	,	,	PUNCT
fnp-3528	1385	19	p.	p.	PROPN
fnp-3528	1385	20	;	;	PUNCT
fnp-3528	1385	21	zhang	zhang	PROPN
fnp-3528	1385	22	,	,	PUNCT
fnp-3528	1385	23	j.	j.	PROPN
fnp-3528	1385	24	;	;	PUNCT
fnp-3528	1385	25	zhang	zhang	PROPN
fnp-3528	1385	26	,	,	PUNCT
fnp-3528	1385	27	x.	x.	PROPN
fnp-3528	1385	28	;	;	PUNCT
fnp-3528	1385	29	bao	bao	PROPN
fnp-3528	1385	30	,	,	PUNCT
fnp-3528	1385	31	y.	y.	PROPN
fnp-3528	1385	32	;	;	PUNCT
fnp-3528	1385	33	yang	yang	PROPN
fnp-3528	1385	34	,	,	PUNCT
fnp-3528	1385	35	x.	x.	PROPN
fnp-3528	1385	36	;	;	PUNCT
fnp-3528	1385	37	wang	wang	PROPN
fnp-3528	1385	38	,	,	PUNCT
fnp-3528	1385	39	p.	p.	NOUN
fnp-3528	1385	40	oxidative	oxidative	ADJ
fnp-3528	1385	41	stress	stress	NOUN
fnp-3528	1385	42	and	and	CCONJ
fnp-3528	1385	43	nf	nf	ADJ
fnp-3528	1385	44	-	-	PUNCT
fnp-3528	1385	45	kappab	kappab	NOUN
fnp-3528	1385	46	signaling	signal	VERB
fnp-3528	1385	47	are	be	AUX
fnp-3528	1385	48	involved	involve	VERB
fnp-3528	1385	49	in	in	ADP
fnp-3528	1385	50	lps	lps	PROPN
fnp-3528	1385	51	induced	induce	VERB
fnp-3528	1385	52	pulmonary	pulmonary	ADJ
fnp-3528	1385	53	dysplasia	dysplasia	NOUN
fnp-3528	1385	54	in	in	ADP
fnp-3528	1385	55	chick	chick	NOUN
fnp-3528	1385	56	embryos	embryos	PROPN
fnp-3528	1385	57	.	.	PUNCT
fnp-3528	1386	1	cell	cell	NOUN
fnp-3528	1386	2	cycle	cycle	NOUN
fnp-3528	1386	3	2018	2018	NUM
fnp-3528	1386	4	,	,	PUNCT
fnp-3528	1386	5	17	17	NUM
fnp-3528	1386	6	,	,	PUNCT
fnp-3528	1386	7	1757	1757	NUM
fnp-3528	1386	8	-	-	SYM
fnp-3528	1386	9	71	71	NUM
fnp-3528	1386	10	.	.	PUNCT
fnp-3528	1387	1	mendonca	mendonca	PROPN
fnp-3528	1387	2	-	-	PUNCT
fnp-3528	1387	3	torres	torres	PROPN
fnp-3528	1387	4	,	,	PUNCT
fnp-3528	1387	5	m.	m.	NOUN
fnp-3528	1387	6	c.	c.	PROPN
fnp-3528	1387	7	;	;	PUNCT
fnp-3528	1387	8	roberts	roberts	PROPN
fnp-3528	1387	9	,	,	PUNCT
fnp-3528	1387	10	s.	s.	PROPN
fnp-3528	1387	11	s.	s.	PROPN
fnp-3528	1387	12	the	the	DET
fnp-3528	1387	13	translocator	translocator	NOUN
fnp-3528	1387	14	protein	protein	NOUN
fnp-3528	1387	15	(	(	PUNCT
fnp-3528	1387	16	tspo	tspo	NOUN
fnp-3528	1387	17	)	)	PUNCT
fnp-3528	1387	18	ligand	ligand	NOUN
fnp-3528	1387	19	pk11195	pk11195	NOUN
fnp-3528	1387	20	induces	induce	VERB
fnp-3528	1387	21	apoptosis	apoptosis	NOUN
fnp-3528	1387	22	and	and	CCONJ
fnp-3528	1387	23	cell	cell	NOUN
fnp-3528	1387	24	cycle	cycle	NOUN
fnp-3528	1387	25	arrest	arrest	NOUN
fnp-3528	1387	26	and	and	CCONJ
fnp-3528	1387	27	sensitizes	sensitize	NOUN
fnp-3528	1387	28	to	to	ADP
fnp-3528	1387	29	chemotherapy	chemotherapy	NOUN
fnp-3528	1387	30	treatment	treatment	NOUN
fnp-3528	1387	31	in	in	ADP
fnp-3528	1387	32	preand	preand	NOUN
fnp-3528	1387	33	post	post	ADJ
fnp-3528	1387	34	-	-	ADJ
fnp-3528	1387	35	relapse	relapse	ADJ
fnp-3528	1387	36	neuroblastoma	neuroblastoma	NOUN
fnp-3528	1387	37	cell	cell	NOUN
fnp-3528	1387	38	lines	line	NOUN
fnp-3528	1387	39	.	.	PUNCT
fnp-3528	1388	1	cancer	cancer	NOUN
fnp-3528	1388	2	biol	biol	PROPN
fnp-3528	1388	3	ther	ther	ADV
fnp-3528	1388	4	2013	2013	NUM
fnp-3528	1388	5	,	,	PUNCT
fnp-3528	1388	6	14	14	NUM
fnp-3528	1388	7	,	,	PUNCT
fnp-3528	1388	8	319	319	NUM
fnp-3528	1388	9	-	-	SYM
fnp-3528	1388	10	26	26	NUM
fnp-3528	1388	11	.	.	PUNCT
fnp-3528	1389	1	wakaumi	wakaumi	PROPN
fnp-3528	1389	2	,	,	PUNCT
fnp-3528	1389	3	m.	m.	NOUN
fnp-3528	1389	4	;	;	PUNCT
fnp-3528	1389	5	ishibashi	ishibashi	PROPN
fnp-3528	1389	6	,	,	PUNCT
fnp-3528	1389	7	k.	k.	PROPN
fnp-3528	1389	8	;	;	PUNCT
fnp-3528	1389	9	ando	ando	PROPN
fnp-3528	1389	10	,	,	PUNCT
fnp-3528	1389	11	h.	h.	PROPN
fnp-3528	1389	12	;	;	PUNCT
fnp-3528	1389	13	kasanuki	kasanuki	PROPN
fnp-3528	1389	14	,	,	PUNCT
fnp-3528	1389	15	h.	h.	PROPN
fnp-3528	1389	16	;	;	PUNCT
fnp-3528	1389	17	tsuruoka	tsuruoka	PROPN
fnp-3528	1389	18	,	,	PUNCT
fnp-3528	1389	19	s.	s.	PROPN
fnp-3528	1389	20	acute	acute	PROPN
fnp-3528	1389	21	digoxin	digoxin	PROPN
fnp-3528	1389	22	loading	loading	NOUN
fnp-3528	1389	23	reduces	reduce	VERB
fnp-3528	1389	24	abca8a	abca8a	PROPN
fnp-3528	1389	25	mrna	mrna	NOUN
fnp-3528	1389	26	expression	expression	NOUN
fnp-3528	1389	27	in	in	ADP
fnp-3528	1389	28	the	the	DET
fnp-3528	1389	29	mouse	mouse	NOUN
fnp-3528	1389	30	liver	liver	NOUN
fnp-3528	1389	31	.	.	PUNCT
fnp-3528	1390	1	clin	clin	PROPN
fnp-3528	1390	2	exp	exp	PROPN
fnp-3528	1390	3	pharmacol	pharmacol	PROPN
fnp-3528	1390	4	physio	physio	PROPN
fnp-3528	1390	5	2005	2005	NUM
fnp-3528	1390	6	,	,	PUNCT
fnp-3528	1390	7	32	32	NUM
fnp-3528	1390	8	,	,	PUNCT
fnp-3528	1390	9	1034	1034	NUM
fnp-3528	1390	10	-	-	SYM
fnp-3528	1390	11	41	41	NUM
fnp-3528	1390	12	.	.	PUNCT
fnp-3528	1391	1	kinting	kinting	PROPN
fnp-3528	1391	2	,	,	PUNCT
fnp-3528	1391	3	s.	s.	PROPN
fnp-3528	1391	4	;	;	PUNCT
fnp-3528	1391	5	hoppner	hoppner	X
fnp-3528	1391	6	,	,	PUNCT
fnp-3528	1391	7	s.	s.	PROPN
fnp-3528	1391	8	;	;	PUNCT
fnp-3528	1391	9	schindlbeck	schindlbeck	NOUN
fnp-3528	1391	10	,	,	PUNCT
fnp-3528	1391	11	u.	u.	PROPN
fnp-3528	1391	12	;	;	PUNCT
fnp-3528	1391	13	forstner	forstner	X
fnp-3528	1391	14	,	,	PUNCT
fnp-3528	1391	15	m.	m.	NOUN
fnp-3528	1391	16	e.	e.	PROPN
fnp-3528	1391	17	;	;	PUNCT
fnp-3528	1391	18	harfst	harfst	PROPN
fnp-3528	1391	19	,	,	PUNCT
fnp-3528	1391	20	j.	j.	PROPN
fnp-3528	1391	21	;	;	PUNCT
fnp-3528	1391	22	wittmann	wittmann	PROPN
fnp-3528	1391	23	,	,	PUNCT
fnp-3528	1391	24	t.	t.	PROPN
fnp-3528	1391	25	;	;	PUNCT
fnp-3528	1391	26	griese	griese	PROPN
fnp-3528	1391	27	,	,	PUNCT
fnp-3528	1391	28	m.	m.	NOUN
fnp-3528	1391	29	functional	functional	ADJ
fnp-3528	1391	30	rescue	rescue	NOUN
fnp-3528	1391	31	of	of	ADP
fnp-3528	1391	32	misfolding	misfolding	NOUN
fnp-3528	1391	33	abca3	abca3	PROPN
fnp-3528	1391	34	mutations	mutation	NOUN
fnp-3528	1391	35	by	by	ADP
fnp-3528	1391	36	small	small	ADJ
fnp-3528	1391	37	molecular	molecular	ADJ
fnp-3528	1391	38	correctors	corrector	NOUN
fnp-3528	1391	39	.	.	PUNCT
fnp-3528	1392	1	hum	hum	ADJ
fnp-3528	1392	2	mol	mol	ADP
fnp-3528	1392	3	genet	genet	PROPN
fnp-3528	1392	4	2018	2018	NUM
fnp-3528	1392	5	,	,	PUNCT
fnp-3528	1392	6	27	27	NUM
fnp-3528	1392	7	,	,	PUNCT
fnp-3528	1392	8	943	943	NUM
fnp-3528	1392	9	-	-	SYM
fnp-3528	1392	10	53	53	NUM
fnp-3528	1392	11	.	.	PUNCT
fnp-3528	1393	1	kinting	kinting	NOUN
fnp-3528	1393	2	,	,	PUNCT
fnp-3528	1393	3	s.	s.	PROPN
fnp-3528	1393	4	;	;	PUNCT
fnp-3528	1393	5	li	li	PROPN
fnp-3528	1393	6	,	,	PUNCT
fnp-3528	1393	7	y.	y.	PROPN
fnp-3528	1393	8	;	;	PUNCT
fnp-3528	1393	9	forstner	forstner	X
fnp-3528	1393	10	,	,	PUNCT
fnp-3528	1393	11	m.	m.	NOUN
fnp-3528	1393	12	;	;	PUNCT
fnp-3528	1393	13	delhommel	delhommel	PROPN
fnp-3528	1393	14	,	,	PUNCT
fnp-3528	1393	15	f.	f.	PROPN
fnp-3528	1393	16	;	;	PUNCT
fnp-3528	1393	17	sattler	sattler	NOUN
fnp-3528	1393	18	,	,	PUNCT
fnp-3528	1393	19	m.	m.	NOUN
fnp-3528	1393	20	;	;	PUNCT
fnp-3528	1393	21	griese	griese	PROPN
fnp-3528	1393	22	,	,	PUNCT
fnp-3528	1393	23	m.	m.	NOUN
fnp-3528	1393	24	potentiation	potentiation	NOUN
fnp-3528	1393	25	of	of	ADP
fnp-3528	1393	26	abca3	abca3	PROPN
fnp-3528	1393	27	lipid	lipid	NOUN
fnp-3528	1393	28	transport	transport	NOUN
fnp-3528	1393	29	function	function	NOUN
fnp-3528	1393	30	by	by	ADP
fnp-3528	1393	31	ivacaftor	ivacaftor	NOUN
fnp-3528	1393	32	and	and	CCONJ
fnp-3528	1393	33	genistein	genistein	NOUN
fnp-3528	1393	34	.	.	PUNCT
fnp-3528	1394	1	j	j	PROPN
fnp-3528	1394	2	cell	cell	PROPN
fnp-3528	1394	3	mol	mol	ADP
fnp-3528	1394	4	med	med	PROPN
fnp-3528	1394	5	2019	2019	NUM
fnp-3528	1394	6	,	,	PUNCT
fnp-3528	1394	7	23	23	NUM
fnp-3528	1394	8	,	,	PUNCT
fnp-3528	1394	9	5225	5225	NUM
fnp-3528	1394	10	-	-	SYM
fnp-3528	1394	11	34	34	NUM
fnp-3528	1394	12	.	.	PUNCT
fnp-3528	1395	1	liu	liu	PROPN
fnp-3528	1395	2	,	,	PUNCT
fnp-3528	1395	3	q.	q.	PROPN
fnp-3528	1395	4	;	;	PUNCT
fnp-3528	1395	5	sabirzhanova	sabirzhanova	PROPN
fnp-3528	1395	6	,	,	PUNCT
fnp-3528	1395	7	i.	i.	NOUN
fnp-3528	1395	8	;	;	PUNCT
fnp-3528	1395	9	bergbower	bergbower	NOUN
fnp-3528	1395	10	,	,	PUNCT
fnp-3528	1395	11	e.	e.	PROPN
fnp-3528	1395	12	a.	a.	PROPN
fnp-3528	1395	13	s.	s.	PROPN
fnp-3528	1395	14	;	;	PUNCT
fnp-3528	1395	15	yanda	yanda	PROPN
fnp-3528	1395	16	,	,	PUNCT
fnp-3528	1395	17	m.	m.	NOUN
fnp-3528	1395	18	;	;	PUNCT
fnp-3528	1395	19	guggino	guggino	PROPN
fnp-3528	1395	20	,	,	PUNCT
fnp-3528	1395	21	w.	w.	PROPN
fnp-3528	1395	22	g.	g.	PROPN
fnp-3528	1395	23	;	;	PUNCT
fnp-3528	1395	24	cebotaru	cebotaru	NOUN
fnp-3528	1395	25	,	,	PUNCT
fnp-3528	1395	26	l.	l.	PROPN
fnp-3528	1395	27	the	the	DET
fnp-3528	1395	28	cftr	cftr	PROPN
fnp-3528	1395	29	corrector	corrector	NOUN
fnp-3528	1395	30	,	,	PUNCT
fnp-3528	1395	31	vx-809	vx-809	PROPN
fnp-3528	1395	32	(	(	PUNCT
fnp-3528	1395	33	lumacaftor	lumacaftor	PROPN
fnp-3528	1395	34	)	)	PUNCT
fnp-3528	1395	35	,	,	PUNCT
fnp-3528	1395	36	rescues	rescue	NOUN
fnp-3528	1395	37	abca4	abca4	VERB
fnp-3528	1395	38	trafficking	traffic	VERB
fnp-3528	1395	39	mutants	mutant	NOUN
fnp-3528	1395	40	:	:	PUNCT
fnp-3528	1395	41	a	a	DET
fnp-3528	1395	42	potential	potential	ADJ
fnp-3528	1395	43	treatment	treatment	NOUN
fnp-3528	1395	44	for	for	ADP
fnp-3528	1395	45	stargardt	stargardt	ADJ
fnp-3528	1395	46	disease	disease	NOUN
fnp-3528	1395	47	.	.	PUNCT
fnp-3528	1396	1	cell	cell	NOUN
fnp-3528	1396	2	physiol	physiol	PROPN
fnp-3528	1396	3	biochem	biochem	PROPN
fnp-3528	1396	4	2019	2019	NUM
fnp-3528	1396	5	,	,	PUNCT
fnp-3528	1396	6	53	53	NUM
fnp-3528	1396	7	,	,	PUNCT
fnp-3528	1396	8	400	400	NUM
fnp-3528	1396	9	-	-	SYM
fnp-3528	1396	10	12	12	NUM
fnp-3528	1396	11	.	.	PUNCT
fnp-3528	1397	1	sabirzhanova	sabirzhanova	PROPN
fnp-3528	1397	2	,	,	PUNCT
fnp-3528	1397	3	i.	i.	PROPN
fnp-3528	1397	4	;	;	PUNCT
fnp-3528	1397	5	lopes	lopes	PROPN
fnp-3528	1397	6	pacheco	pacheco	PROPN
fnp-3528	1397	7	,	,	PUNCT
fnp-3528	1397	8	m.	m.	NOUN
fnp-3528	1397	9	;	;	PUNCT
fnp-3528	1397	10	rapino	rapino	PROPN
fnp-3528	1397	11	,	,	PUNCT
fnp-3528	1397	12	d.	d.	PROPN
fnp-3528	1397	13	;	;	PUNCT
fnp-3528	1397	14	grover	grover	PROPN
fnp-3528	1397	15	,	,	PUNCT
fnp-3528	1397	16	r.	r.	PROPN
fnp-3528	1397	17	;	;	PUNCT
fnp-3528	1397	18	handa	handa	PROPN
fnp-3528	1397	19	,	,	PUNCT
fnp-3528	1397	20	j.	j.	PROPN
fnp-3528	1397	21	t.	t.	PROPN
fnp-3528	1397	22	;	;	PUNCT
fnp-3528	1397	23	guggino	guggino	PROPN
fnp-3528	1397	24	,	,	PUNCT
fnp-3528	1397	25	w.	w.	PROPN
fnp-3528	1397	26	b.	b.	PROPN
fnp-3528	1397	27	;	;	PUNCT
fnp-3528	1397	28	cebotaru	cebotaru	PROPN
fnp-3528	1397	29	,	,	PUNCT
fnp-3528	1397	30	l.	l.	PROPN
fnp-3528	1397	31	rescuing	rescue	VERB
fnp-3528	1397	32	trafficking	traffic	VERB
fnp-3528	1397	33	mutants	mutant	NOUN
fnp-3528	1397	34	of	of	ADP
fnp-3528	1397	35	the	the	DET
fnp-3528	1397	36	atp	atp	NOUN
fnp-3528	1397	37	-	-	PUNCT
fnp-3528	1397	38	binding	bind	VERB
fnp-3528	1397	39	cassette	cassette	NOUN
fnp-3528	1397	40	protein	protein	NOUN
fnp-3528	1397	41	,	,	PUNCT
fnp-3528	1397	42	abca4	abca4	ADJ
fnp-3528	1397	43	,	,	PUNCT
fnp-3528	1397	44	with	with	ADP
fnp-3528	1397	45	small	small	ADJ
fnp-3528	1397	46	molecule	molecule	NOUN
fnp-3528	1397	47	correctors	corrector	NOUN
fnp-3528	1397	48	as	as	ADP
fnp-3528	1397	49	a	a	DET
fnp-3528	1397	50	treatment	treatment	NOUN
fnp-3528	1397	51	for	for	ADP
fnp-3528	1397	52	stargardt	stargardt	ADJ
fnp-3528	1397	53	eye	eye	NOUN
fnp-3528	1397	54	disease	disease	NOUN
fnp-3528	1397	55	.	.	PUNCT
fnp-3528	1398	1	j	j	PROPN
fnp-3528	1398	2	biol	biol	PROPN
fnp-3528	1398	3	chem	chem	NOUN
fnp-3528	1398	4	2015	2015	NUM
fnp-3528	1398	5	,	,	PUNCT
fnp-3528	1398	6	290	290	NUM
fnp-3528	1398	7	,	,	PUNCT
fnp-3528	1398	8	19743	19743	NUM
fnp-3528	1398	9	-	-	SYM
fnp-3528	1398	10	55	55	NUM
fnp-3528	1398	11	.	.	PUNCT
fnp-3528	1399	1	lopes	lopes	PROPN
fnp-3528	1399	2	-	-	PUNCT
fnp-3528	1399	3	pacheco	pacheco	PROPN
fnp-3528	1399	4	,	,	PUNCT
fnp-3528	1399	5	m.	m.	NOUN
fnp-3528	1399	6	;	;	PUNCT
fnp-3528	1399	7	sabirzhanova	sabirzhanova	PROPN
fnp-3528	1399	8	,	,	PUNCT
fnp-3528	1399	9	i.	i.	PROPN
fnp-3528	1399	10	;	;	PUNCT
fnp-3528	1399	11	rapino	rapino	PROPN
fnp-3528	1399	12	,	,	PUNCT
fnp-3528	1399	13	d.	d.	PROPN
fnp-3528	1399	14	;	;	PUNCT
fnp-3528	1399	15	morales	morale	NOUN
fnp-3528	1399	16	,	,	PUNCT
fnp-3528	1399	17	m.	m.	NOUN
fnp-3528	1399	18	m.	m.	NOUN
fnp-3528	1399	19	;	;	PUNCT
fnp-3528	1399	20	guggino	guggino	PROPN
fnp-3528	1399	21	,	,	PUNCT
fnp-3528	1399	22	w.	w.	PROPN
fnp-3528	1399	23	b.	b.	PROPN
fnp-3528	1399	24	;	;	PUNCT
fnp-3528	1399	25	cebotaru	cebotaru	NOUN
fnp-3528	1399	26	,	,	PUNCT
fnp-3528	1399	27	l.	l.	PROPN
fnp-3528	1399	28	correctors	corrector	NOUN
fnp-3528	1399	29	rescue	rescue	VERB
fnp-3528	1399	30	cftr	cftr	NOUN
fnp-3528	1399	31	mutations	mutation	NOUN
fnp-3528	1399	32	in	in	ADP
fnp-3528	1399	33	nucleotide	nucleotide	NOUN
fnp-3528	1399	34	-	-	PUNCT
fnp-3528	1399	35	binding	bind	VERB
fnp-3528	1399	36	domain	domain	NOUN
fnp-3528	1399	37	1	1	NUM
fnp-3528	1399	38	(	(	PUNCT
fnp-3528	1399	39	nbd1	nbd1	PROPN
fnp-3528	1399	40	)	)	PUNCT
fnp-3528	1399	41	by	by	ADP
fnp-3528	1399	42	modulating	modulate	VERB
fnp-3528	1399	43	proteostasis	proteostasis	NOUN
fnp-3528	1399	44	.	.	PUNCT
fnp-3528	1400	1	chembiochem	chembiochem	PROPN
fnp-3528	1400	2	2016	2016	NUM
fnp-3528	1400	3	,	,	PUNCT
fnp-3528	1400	4	17	17	NUM
fnp-3528	1400	5	,	,	PUNCT
fnp-3528	1400	6	493	493	NUM
fnp-3528	1400	7	-	-	SYM
fnp-3528	1400	8	505	505	NUM
fnp-3528	1400	9	.	.	PUNCT
fnp-3528	1401	1	wang	wang	PROPN
fnp-3528	1401	2	,	,	PUNCT
fnp-3528	1401	3	y.	y.	PROPN
fnp-3528	1401	4	;	;	PUNCT
fnp-3528	1401	5	loo	loo	NOUN
fnp-3528	1401	6	,	,	PUNCT
fnp-3528	1401	7	t.	t.	PROPN
fnp-3528	1401	8	w.	w.	PROPN
fnp-3528	1401	9	;	;	PUNCT
fnp-3528	1401	10	bartlett	bartlett	PROPN
fnp-3528	1401	11	,	,	PUNCT
fnp-3528	1401	12	m.	m.	PROPN
fnp-3528	1401	13	c.	c.	PROPN
fnp-3528	1401	14	;	;	PUNCT
fnp-3528	1401	15	clarke	clarke	PROPN
fnp-3528	1401	16	,	,	PUNCT
fnp-3528	1401	17	d.	d.	PROPN
fnp-3528	1401	18	m.	m.	NOUN
fnp-3528	1401	19	correctors	corrector	NOUN
fnp-3528	1401	20	promote	promote	VERB
fnp-3528	1401	21	maturation	maturation	NOUN
fnp-3528	1401	22	of	of	ADP
fnp-3528	1401	23	cystic	cystic	ADJ
fnp-3528	1401	24	fibrosis	fibrosis	NOUN
fnp-3528	1401	25	transmembrane	transmembrane	NOUN
fnp-3528	1401	26	conductance	conductance	NOUN
fnp-3528	1401	27	regulator	regulator	NOUN
fnp-3528	1401	28	(	(	PUNCT
fnp-3528	1401	29	cftr)-processing	cftr)-processing	PROPN
fnp-3528	1401	30	mutants	mutant	NOUN
fnp-3528	1401	31	by	by	ADP
fnp-3528	1401	32	binding	bind	VERB
fnp-3528	1401	33	to	to	ADP
fnp-3528	1401	34	the	the	DET
fnp-3528	1401	35	protein	protein	NOUN
fnp-3528	1401	36	.	.	PUNCT
fnp-3528	1402	1	j	j	PROPN
fnp-3528	1402	2	biol	biol	PROPN
fnp-3528	1402	3	chem	chem	NOUN
fnp-3528	1402	4	2007	2007	NUM
fnp-3528	1402	5	,	,	PUNCT
fnp-3528	1402	6	282	282	NUM
fnp-3528	1402	7	,	,	PUNCT
fnp-3528	1402	8	33247	33247	NUM
fnp-3528	1402	9	-	-	SYM
fnp-3528	1402	10	51	51	NUM
fnp-3528	1402	11	.	.	PUNCT
fnp-3528	1403	1	lin	lin	PROPN
fnp-3528	1403	2	,	,	PUNCT
fnp-3528	1403	3	s.	s.	PROPN
fnp-3528	1403	4	;	;	PUNCT
fnp-3528	1403	5	zhou	zhou	PROPN
fnp-3528	1403	6	,	,	PUNCT
fnp-3528	1403	7	c.	c.	PROPN
fnp-3528	1403	8	;	;	PUNCT
fnp-3528	1403	9	neufeld	neufeld	PROPN
fnp-3528	1403	10	,	,	PUNCT
fnp-3528	1403	11	e.	e.	PROPN
fnp-3528	1403	12	;	;	PUNCT
fnp-3528	1403	13	wang	wang	PROPN
fnp-3528	1403	14	,	,	PUNCT
fnp-3528	1403	15	y.	y.	PROPN
fnp-3528	1403	16	h.	h.	PROPN
fnp-3528	1403	17	;	;	PUNCT
fnp-3528	1403	18	xu	xu	PROPN
fnp-3528	1403	19	,	,	PUNCT
fnp-3528	1403	20	s.	s.	PROPN
fnp-3528	1403	21	w.	w.	PROPN
fnp-3528	1403	22	;	;	PUNCT
fnp-3528	1403	23	lu	lu	PROPN
fnp-3528	1403	24	,	,	PUNCT
fnp-3528	1403	25	l.	l.	PROPN
fnp-3528	1403	26	;	;	PUNCT
fnp-3528	1403	27	wang	wang	PROPN
fnp-3528	1403	28	,	,	PUNCT
fnp-3528	1403	29	y.	y.	PROPN
fnp-3528	1403	30	;	;	PUNCT
fnp-3528	1403	31	liu	liu	PROPN
fnp-3528	1403	32	,	,	PUNCT
fnp-3528	1403	33	z.	z.	PROPN
fnp-3528	1403	34	p.	p.	PROPN
fnp-3528	1403	35	;	;	PUNCT
fnp-3528	1403	36	li	li	PROPN
fnp-3528	1403	37	,	,	PUNCT
fnp-3528	1403	38	d.	d.	PROPN
fnp-3528	1403	39	;	;	PUNCT
fnp-3528	1403	40	li	li	PROPN
fnp-3528	1403	41	,	,	PUNCT
fnp-3528	1403	42	c.	c.	PROPN
fnp-3528	1403	43	;	;	PUNCT
fnp-3528	1403	44	chen	chen	PROPN
fnp-3528	1403	45	,	,	PUNCT
fnp-3528	1403	46	s.	s.	PROPN
fnp-3528	1403	47	;	;	PUNCT
fnp-3528	1403	48	le	le	X
fnp-3528	1403	49	,	,	PUNCT
fnp-3528	1403	50	k.	k.	PROPN
fnp-3528	1403	51	;	;	PUNCT
fnp-3528	1403	52	huang	huang	PROPN
fnp-3528	1403	53	,	,	PUNCT
fnp-3528	1403	54	h.	h.	PROPN
fnp-3528	1403	55	;	;	PUNCT
fnp-3528	1403	56	liu	liu	PROPN
fnp-3528	1403	57	,	,	PUNCT
fnp-3528	1403	58	p.	p.	PROPN
fnp-3528	1403	59	;	;	PUNCT
fnp-3528	1403	60	moss	moss	PROPN
fnp-3528	1403	61	,	,	PUNCT
fnp-3528	1403	62	j.	j.	PROPN
fnp-3528	1403	63	;	;	PUNCT
fnp-3528	1403	64	vaughan	vaughan	PROPN
fnp-3528	1403	65	,	,	PUNCT
fnp-3528	1403	66	m.	m.	NOUN
fnp-3528	1403	67	;	;	PUNCT
fnp-3528	1403	68	shen	shen	PROPN
fnp-3528	1403	69	,	,	PUNCT
fnp-3528	1403	70	x.	x.	PROPN
fnp-3528	1403	71	big1	big1	PROPN
fnp-3528	1403	72	,	,	PUNCT
fnp-3528	1403	73	a	a	DET
fnp-3528	1403	74	brefeldin	brefeldin	NOUN
fnp-3528	1403	75	a	a	PRON
fnp-3528	1403	76	-	-	PUNCT
fnp-3528	1403	77	inhibited	inhibit	VERB
fnp-3528	1403	78	guanine	guanine	NOUN
fnp-3528	1403	79	nucleotide	nucleotide	NOUN
fnp-3528	1403	80	-	-	PUNCT
fnp-3528	1403	81	exchange	exchange	NOUN
fnp-3528	1403	82	protein	protein	NOUN
fnp-3528	1403	83	modulates	modulate	VERB
fnp-3528	1403	84	atp	atp	NOUN
fnp-3528	1403	85	-	-	PUNCT
fnp-3528	1403	86	binding	bind	VERB
fnp-3528	1403	87	cassette	cassette	NOUN
fnp-3528	1403	88	transporter	transporter	NOUN
fnp-3528	1403	89	a-1	a-1	NOUN
fnp-3528	1403	90	trafficking	trafficking	NOUN
fnp-3528	1403	91	and	and	CCONJ
fnp-3528	1403	92	function	function	NOUN
fnp-3528	1403	93	.	.	PUNCT
fnp-3528	1404	1	arterioscler	arterioscler	PROPN
fnp-3528	1404	2	thromb	thromb	PROPN
fnp-3528	1404	3	vasc	vasc	PROPN
fnp-3528	1404	4	biol	biol	PROPN
fnp-3528	1404	5	2013	2013	NUM
fnp-3528	1404	6	,	,	PUNCT
fnp-3528	1404	7	33	33	NUM
fnp-3528	1404	8	,	,	PUNCT
fnp-3528	1404	9	e31	e31	PROPN
fnp-3528	1404	10	-	-	SYM
fnp-3528	1404	11	8	8	NUM
fnp-3528	1404	12	.	.	PUNCT
fnp-3528	1405	1	remaley	remaley	PROPN
fnp-3528	1405	2	,	,	PUNCT
fnp-3528	1405	3	a.	a.	NOUN
fnp-3528	1405	4	t.	t.	PROPN
fnp-3528	1405	5	;	;	PUNCT
fnp-3528	1405	6	schumacher	schumacher	PROPN
fnp-3528	1405	7	,	,	PUNCT
fnp-3528	1405	8	u.	u.	PROPN
fnp-3528	1405	9	k.	k.	PROPN
fnp-3528	1405	10	;	;	PUNCT
fnp-3528	1405	11	stonik	stonik	PROPN
fnp-3528	1405	12	,	,	PUNCT
fnp-3528	1405	13	j.	j.	PROPN
fnp-3528	1405	14	a.	a.	PROPN
fnp-3528	1405	15	;	;	PUNCT
fnp-3528	1405	16	farsi	farsi	PROPN
fnp-3528	1405	17	,	,	PUNCT
fnp-3528	1405	18	b.	b.	PROPN
fnp-3528	1405	19	d.	d.	PROPN
fnp-3528	1405	20	;	;	PUNCT
fnp-3528	1405	21	nazih	nazih	PROPN
fnp-3528	1405	22	,	,	PUNCT
fnp-3528	1405	23	h.	h.	PROPN
fnp-3528	1405	24	;	;	PUNCT
fnp-3528	1405	25	brewer	brewer	PROPN
fnp-3528	1405	26	,	,	PUNCT
fnp-3528	1405	27	h.	h.	PROPN
fnp-3528	1405	28	b.	b.	PROPN
fnp-3528	1405	29	,	,	PUNCT
fnp-3528	1405	30	jr	jr	PROPN
fnp-3528	1405	31	.	.	PROPN
fnp-3528	1405	32	decreased	decrease	VERB
fnp-3528	1405	33	reverse	reverse	ADJ
fnp-3528	1405	34	cholesterol	cholesterol	NOUN
fnp-3528	1405	35	transport	transport	NOUN
fnp-3528	1405	36	from	from	ADP
fnp-3528	1405	37	tangier	tangy	ADJ
fnp-3528	1405	38	disease	disease	NOUN
fnp-3528	1405	39	fibroblasts	fibroblast	VERB
fnp-3528	1405	40	.	.	PUNCT
fnp-3528	1406	1	acceptor	acceptor	NOUN
fnp-3528	1406	2	specificity	specificity	NOUN
fnp-3528	1406	3	and	and	CCONJ
fnp-3528	1406	4	effect	effect	NOUN
fnp-3528	1406	5	of	of	ADP
fnp-3528	1406	6	brefeldin	brefeldin	VERB
fnp-3528	1406	7	on	on	ADP
fnp-3528	1406	8	lipid	lipid	NOUN
fnp-3528	1406	9	efflux	efflux	NOUN
fnp-3528	1406	10	.	.	PUNCT
fnp-3528	1407	1	arterioscler	arterioscler	PROPN
fnp-3528	1407	2	thromb	thromb	PROPN
fnp-3528	1407	3	vasc	vasc	PROPN
fnp-3528	1407	4	biol	biol	PROPN
fnp-3528	1407	5	1997	1997	NUM
fnp-3528	1407	6	,	,	PUNCT
fnp-3528	1407	7	17	17	NUM
fnp-3528	1407	8	,	,	PUNCT
fnp-3528	1407	9	1813	1813	NUM
fnp-3528	1407	10	-	-	SYM
fnp-3528	1407	11	21	21	NUM
fnp-3528	1407	12	.	.	PUNCT
fnp-3528	1408	1	mendez	mendez	PROPN
fnp-3528	1408	2	,	,	PUNCT
fnp-3528	1408	3	a.	a.	PROPN
fnp-3528	1408	4	j.	j.	PROPN
fnp-3528	1408	5	monensin	monensin	PROPN
fnp-3528	1408	6	and	and	CCONJ
fnp-3528	1408	7	brefeldin	brefeldin	VERB
fnp-3528	1408	8	a	a	DET
fnp-3528	1408	9	inhibit	inhibit	NOUN
fnp-3528	1408	10	high	high	ADJ
fnp-3528	1408	11	density	density	NOUN
fnp-3528	1408	12	lipoprotein	lipoprotein	ADJ
fnp-3528	1408	13	-	-	PUNCT
fnp-3528	1408	14	mediated	mediate	VERB
fnp-3528	1408	15	cholesterol	cholesterol	NOUN
fnp-3528	1408	16	efflux	efflux	VERB
fnp-3528	1408	17	from	from	ADP
fnp-3528	1408	18	cholesterol	cholesterol	NOUN
fnp-3528	1408	19	-	-	PUNCT
fnp-3528	1408	20	enriched	enrich	VERB
fnp-3528	1408	21	cells	cell	NOUN
fnp-3528	1408	22	.	.	PUNCT
fnp-3528	1409	1	implications	implication	NOUN
fnp-3528	1409	2	for	for	ADP
fnp-3528	1409	3	intracellular	intracellular	ADJ
fnp-3528	1409	4	cholesterol	cholesterol	NOUN
fnp-3528	1409	5	transport	transport	NOUN
fnp-3528	1409	6	.	.	PUNCT
fnp-3528	1410	1	j	j	PROPN
fnp-3528	1410	2	biol	biol	PROPN
fnp-3528	1410	3	chem	chem	NOUN
fnp-3528	1410	4	1995	1995	NUM
fnp-3528	1410	5	,	,	PUNCT
fnp-3528	1410	6	270	270	NUM
fnp-3528	1410	7	,	,	PUNCT
fnp-3528	1410	8	5891	5891	NUM
fnp-3528	1410	9	-	-	SYM
fnp-3528	1410	10	900	900	NUM
fnp-3528	1410	11	.	.	PUNCT
fnp-3528	1411	1	neufeld	neufeld	PROPN
fnp-3528	1411	2	,	,	PUNCT
fnp-3528	1411	3	e.	e.	PROPN
fnp-3528	1411	4	b.	b.	PROPN
fnp-3528	1411	5	;	;	PUNCT
fnp-3528	1411	6	remaley	remaley	PROPN
fnp-3528	1411	7	,	,	PUNCT
fnp-3528	1411	8	a.	a.	NOUN
fnp-3528	1411	9	t.	t.	PROPN
fnp-3528	1411	10	;	;	PUNCT
fnp-3528	1411	11	demosky	demosky	PROPN
fnp-3528	1411	12	,	,	PUNCT
fnp-3528	1411	13	s.	s.	PROPN
fnp-3528	1411	14	j.	j.	PROPN
fnp-3528	1411	15	;	;	PUNCT
fnp-3528	1411	16	stonik	stonik	PROPN
fnp-3528	1411	17	,	,	PUNCT
fnp-3528	1411	18	j.	j.	PROPN
fnp-3528	1411	19	a.	a.	PROPN
fnp-3528	1411	20	;	;	PUNCT
fnp-3528	1411	21	cooney	cooney	PROPN
fnp-3528	1411	22	,	,	PUNCT
fnp-3528	1411	23	a.	a.	NOUN
fnp-3528	1411	24	m.	m.	NOUN
fnp-3528	1411	25	;	;	PUNCT
fnp-3528	1411	26	comly	comly	ADV
fnp-3528	1411	27	,	,	PUNCT
fnp-3528	1411	28	m.	m.	NOUN
fnp-3528	1411	29	;	;	PUNCT
fnp-3528	1411	30	dwyer	dwyer	PROPN
fnp-3528	1411	31	,	,	PUNCT
fnp-3528	1411	32	n.	n.	PROPN
fnp-3528	1411	33	k.	k.	PROPN
fnp-3528	1411	34	;	;	PUNCT
fnp-3528	1411	35	zhang	zhang	PROPN
fnp-3528	1411	36	,	,	PUNCT
fnp-3528	1411	37	m.	m.	NOUN
fnp-3528	1411	38	;	;	PUNCT
fnp-3528	1411	39	blanchette	blanchette	PROPN
fnp-3528	1411	40	-	-	PUNCT
fnp-3528	1411	41	mackie	mackie	PROPN
fnp-3528	1411	42	,	,	PUNCT
fnp-3528	1411	43	j.	j.	PROPN
fnp-3528	1411	44	;	;	PUNCT
fnp-3528	1411	45	santamarina	santamarina	ADJ
fnp-3528	1411	46	-	-	PUNCT
fnp-3528	1411	47	fojo	fojo	NOUN
fnp-3528	1411	48	,	,	PUNCT
fnp-3528	1411	49	s.	s.	PROPN
fnp-3528	1411	50	;	;	PUNCT
fnp-3528	1411	51	brewer	brewer	PROPN
fnp-3528	1411	52	,	,	PUNCT
fnp-3528	1411	53	h.	h.	PROPN
fnp-3528	1411	54	b.	b.	PROPN
fnp-3528	1411	55	,	,	PUNCT
fnp-3528	1411	56	jr	jr	PROPN
fnp-3528	1411	57	.	.	PUNCT
fnp-3528	1411	58	cellular	cellular	ADJ
fnp-3528	1411	59	localization	localization	NOUN
fnp-3528	1411	60	and	and	CCONJ
fnp-3528	1411	61	trafficking	trafficking	NOUN
fnp-3528	1411	62	of	of	ADP
fnp-3528	1411	63	the	the	DET
fnp-3528	1411	64	human	human	ADJ
fnp-3528	1411	65	abca1	abca1	NOUN
fnp-3528	1411	66	transporter	transporter	NOUN
fnp-3528	1411	67	.	.	PUNCT
fnp-3528	1412	1	j	j	PROPN
fnp-3528	1412	2	biol	biol	PROPN
fnp-3528	1412	3	chem	chem	NOUN
fnp-3528	1412	4	2001	2001	NUM
fnp-3528	1412	5	,	,	PUNCT
fnp-3528	1412	6	276	276	NUM
fnp-3528	1412	7	,	,	PUNCT
fnp-3528	1412	8	27584	27584	NUM
fnp-3528	1412	9	-	-	SYM
fnp-3528	1412	10	90	90	NUM
fnp-3528	1412	11	.	.	PUNCT
fnp-3528	1412	12	field	field	NOUN
fnp-3528	1412	13	,	,	PUNCT
fnp-3528	1412	14	f.	f.	PROPN
fnp-3528	1412	15	j.	j.	PROPN
fnp-3528	1412	16	;	;	PUNCT
fnp-3528	1412	17	born	bear	VERB
fnp-3528	1412	18	,	,	PUNCT
fnp-3528	1412	19	e.	e.	PROPN
fnp-3528	1412	20	;	;	PUNCT
fnp-3528	1413	1	chen	chen	PROPN
fnp-3528	1413	2	,	,	PUNCT
fnp-3528	1413	3	h.	h.	PROPN
fnp-3528	1413	4	;	;	PUNCT
fnp-3528	1413	5	murthy	murthy	PROPN
fnp-3528	1413	6	,	,	PUNCT
fnp-3528	1413	7	s.	s.	PROPN
fnp-3528	1413	8	;	;	PUNCT
fnp-3528	1413	9	mathur	mathur	PROPN
fnp-3528	1413	10	,	,	PUNCT
fnp-3528	1413	11	s.	s.	PROPN
fnp-3528	1413	12	n.	n.	PROPN
fnp-3528	1413	13	esterification	esterification	NOUN
fnp-3528	1413	14	of	of	ADP
fnp-3528	1413	15	plasma	plasma	NOUN
fnp-3528	1413	16	membrane	membrane	NOUN
fnp-3528	1413	17	cholesterol	cholesterol	NOUN
fnp-3528	1413	18	and	and	CCONJ
fnp-3528	1413	19	triacylglycerol	triacylglycerol	NOUN
fnp-3528	1413	20	-	-	PUNCT
fnp-3528	1413	21	rich	rich	ADJ
fnp-3528	1413	22	lipoprotein	lipoprotein	ADJ
fnp-3528	1413	23	secretion	secretion	NOUN
fnp-3528	1413	24	in	in	ADP
fnp-3528	1413	25	caco-2	caco-2	NUM
fnp-3528	1413	26	cells	cell	NOUN
fnp-3528	1413	27	:	:	PUNCT
fnp-3528	1413	28	possible	possible	ADJ
fnp-3528	1413	29	role	role	NOUN
fnp-3528	1413	30	of	of	ADP
fnp-3528	1413	31	p	p	NOUN
fnp-3528	1413	32	-	-	PUNCT
fnp-3528	1413	33	glycoprotein	glycoprotein	NOUN
fnp-3528	1413	34	.	.	PUNCT
fnp-3528	1414	1	j	j	PROPN
fnp-3528	1414	2	lipid	lipid	PROPN
fnp-3528	1414	3	res	re	NOUN
fnp-3528	1414	4	1995	1995	NUM
fnp-3528	1414	5	,	,	PUNCT
fnp-3528	1414	6	36	36	NUM
fnp-3528	1414	7	,	,	PUNCT
fnp-3528	1414	8	1533	1533	NUM
fnp-3528	1414	9	-	-	SYM
fnp-3528	1414	10	43	43	NUM
fnp-3528	1414	11	.	.	PUNCT
fnp-3528	1415	1	castilho	castilho	PROPN
fnp-3528	1415	2	,	,	PUNCT
fnp-3528	1415	3	g.	g.	PROPN
fnp-3528	1415	4	;	;	PUNCT
fnp-3528	1415	5	okuda	okuda	PROPN
fnp-3528	1415	6	,	,	PUNCT
fnp-3528	1415	7	l.	l.	PROPN
fnp-3528	1415	8	s.	s.	PROPN
fnp-3528	1415	9	;	;	PUNCT
fnp-3528	1415	10	pinto	pinto	PROPN
fnp-3528	1415	11	,	,	PUNCT
fnp-3528	1415	12	r.	r.	PROPN
fnp-3528	1415	13	s.	s.	PROPN
fnp-3528	1415	14	;	;	PUNCT
fnp-3528	1415	15	iborra	iborra	PROPN
fnp-3528	1415	16	,	,	PUNCT
fnp-3528	1415	17	r.	r.	PROPN
fnp-3528	1415	18	t.	t.	PROPN
fnp-3528	1415	19	;	;	PUNCT
fnp-3528	1415	20	nakandakare	nakandakare	PROPN
fnp-3528	1415	21	,	,	PUNCT
fnp-3528	1415	22	e.	e.	PROPN
fnp-3528	1415	23	r.	r.	PROPN
fnp-3528	1415	24	;	;	PUNCT
fnp-3528	1415	25	santos	santos	PROPN
fnp-3528	1415	26	,	,	PUNCT
fnp-3528	1415	27	c.	c.	PROPN
fnp-3528	1415	28	x.	x.	PROPN
fnp-3528	1415	29	;	;	PUNCT
fnp-3528	1415	30	laurindo	laurindo	PROPN
fnp-3528	1415	31	,	,	PUNCT
fnp-3528	1415	32	f.	f.	PROPN
fnp-3528	1415	33	r.	r.	PROPN
fnp-3528	1415	34	;	;	PUNCT
fnp-3528	1415	35	passarelli	passarelli	PROPN
fnp-3528	1415	36	,	,	PUNCT
fnp-3528	1415	37	m.	m.	NOUN
fnp-3528	1415	38	er	er	INTJ
fnp-3528	1415	39	stress	stress	NOUN
fnp-3528	1415	40	is	be	AUX
fnp-3528	1415	41	associated	associate	VERB
fnp-3528	1415	42	with	with	ADP
fnp-3528	1415	43	reduced	reduce	VERB
fnp-3528	1415	44	abca-1	abca-1	NUM
fnp-3528	1415	45	protein	protein	NOUN
fnp-3528	1415	46	levels	level	NOUN
fnp-3528	1415	47	in	in	ADP
fnp-3528	1415	48	macrophages	macrophage	NOUN
fnp-3528	1415	49	treated	treat	VERB
fnp-3528	1415	50	with	with	ADP
fnp-3528	1415	51	advanced	advanced	ADJ
fnp-3528	1415	52	glycated	glycate	VERB
fnp-3528	1415	53	albumin	albumin	ADJ
fnp-3528	1415	54	reversal	reversal	NOUN
fnp-3528	1415	55	by	by	ADP
fnp-3528	1415	56	a	a	DET
fnp-3528	1415	57	chemical	chemical	NOUN
fnp-3528	1415	58	chaperone	chaperone	NOUN
fnp-3528	1415	59	.	.	PUNCT
fnp-3528	1416	1	int	int	PROPN
fnp-3528	1416	2	j	j	PROPN
fnp-3528	1416	3	biochem	biochem	PROPN
fnp-3528	1416	4	cell	cell	NOUN
fnp-3528	1416	5	biol	biol	PROPN
fnp-3528	1416	6	2012	2012	NUM
fnp-3528	1416	7	,	,	PUNCT
fnp-3528	1416	8	44	44	NUM
fnp-3528	1416	9	,	,	PUNCT
fnp-3528	1416	10	1078	1078	NUM
fnp-3528	1416	11	-	-	SYM
fnp-3528	1416	12	86	86	NUM
fnp-3528	1416	13	.	.	PUNCT
fnp-3528	1417	1	singaraja	singaraja	PROPN
fnp-3528	1417	2	,	,	PUNCT
fnp-3528	1417	3	r.	r.	PROPN
fnp-3528	1417	4	r.	r.	PROPN
fnp-3528	1417	5	;	;	PUNCT
fnp-3528	1418	1	kang	kang	PROPN
fnp-3528	1418	2	,	,	PUNCT
fnp-3528	1418	3	m.	m.	PROPN
fnp-3528	1418	4	h.	h.	PROPN
fnp-3528	1418	5	;	;	PUNCT
fnp-3528	1418	6	vaid	vaid	PROPN
fnp-3528	1418	7	,	,	PUNCT
fnp-3528	1418	8	k.	k.	PROPN
fnp-3528	1418	9	;	;	PUNCT
fnp-3528	1418	10	sanders	sanders	PROPN
fnp-3528	1418	11	,	,	PUNCT
fnp-3528	1418	12	s.	s.	PROPN
fnp-3528	1418	13	s.	s.	PROPN
fnp-3528	1418	14	;	;	PUNCT
fnp-3528	1418	15	vilas	vilas	PROPN
fnp-3528	1418	16	,	,	PUNCT
fnp-3528	1418	17	g.	g.	PROPN
fnp-3528	1418	18	l.	l.	PROPN
fnp-3528	1418	19	;	;	PUNCT
fnp-3528	1418	20	arstikaitis	arstikaitis	NOUN
fnp-3528	1418	21	,	,	PUNCT
fnp-3528	1418	22	p.	p.	NOUN
fnp-3528	1418	23	;	;	PUNCT
fnp-3528	1418	24	coutinho	coutinho	PROPN
fnp-3528	1418	25	,	,	PUNCT
fnp-3528	1418	26	j.	j.	PROPN
fnp-3528	1418	27	;	;	PUNCT
fnp-3528	1418	28	drisdel	drisdel	PROPN
fnp-3528	1418	29	,	,	PUNCT
fnp-3528	1418	30	r.	r.	PROPN
fnp-3528	1418	31	c.	c.	PROPN
fnp-3528	1418	32	;	;	PUNCT
fnp-3528	1418	33	el	el	PROPN
fnp-3528	1418	34	-	-	PROPN
fnp-3528	1418	35	husseini	husseini	PROPN
fnp-3528	1418	36	ael	ael	PROPN
fnp-3528	1418	37	,	,	PUNCT
fnp-3528	1418	38	d.	d.	PROPN
fnp-3528	1418	39	;	;	PUNCT
fnp-3528	1418	40	green	green	PROPN
fnp-3528	1418	41	,	,	PUNCT
fnp-3528	1418	42	w.	w.	PROPN
fnp-3528	1418	43	n.	n.	PROPN
fnp-3528	1418	44	;	;	PUNCT
fnp-3528	1418	45	berthiaume	berthiaume	PROPN
fnp-3528	1418	46	,	,	PUNCT
fnp-3528	1418	47	l.	l.	PROPN
fnp-3528	1418	48	;	;	PUNCT
fnp-3528	1418	49	hayden	hayden	PROPN
fnp-3528	1418	50	,	,	PUNCT
fnp-3528	1418	51	m.	m.	PROPN
fnp-3528	1418	52	r.	r.	PROPN
fnp-3528	1418	53	palmitoylation	palmitoylation	PROPN
fnp-3528	1418	54	of	of	ADP
fnp-3528	1418	55	atp	atp	PROPN
fnp-3528	1418	56	-	-	PUNCT
fnp-3528	1418	57	binding	bind	VERB
fnp-3528	1418	58	cassette	cassette	NOUN
fnp-3528	1418	59	transporter	transporter	NOUN
fnp-3528	1418	60	a1	a1	NOUN
fnp-3528	1418	61	is	be	AUX
fnp-3528	1418	62	essential	essential	ADJ
fnp-3528	1418	63	for	for	ADP
fnp-3528	1418	64	its	its	PRON
fnp-3528	1418	65	trafficking	trafficking	NOUN
fnp-3528	1418	66	and	and	CCONJ
fnp-3528	1418	67	function	function	NOUN
fnp-3528	1418	68	.	.	PUNCT
fnp-3528	1419	1	circ	circ	PROPN
fnp-3528	1419	2	res	re	NOUN
fnp-3528	1419	3	2009	2009	NUM
fnp-3528	1419	4	,	,	PUNCT
fnp-3528	1419	5	105	105	NUM
fnp-3528	1419	6	,	,	PUNCT
fnp-3528	1419	7	138	138	NUM
fnp-3528	1419	8	-	-	SYM
fnp-3528	1419	9	47	47	NUM
fnp-3528	1419	10	.	.	PUNCT
fnp-3528	1420	1	jones	jones	PROPN
fnp-3528	1420	2	,	,	PUNCT
fnp-3528	1420	3	r.	r.	PROPN
fnp-3528	1420	4	j.	j.	PROPN
fnp-3528	1420	5	;	;	PUNCT
fnp-3528	1420	6	gu	gu	PROPN
fnp-3528	1420	7	,	,	PUNCT
fnp-3528	1420	8	d.	d.	PROPN
fnp-3528	1420	9	;	;	PUNCT
fnp-3528	1420	10	bjorklund	bjorklund	VERB
fnp-3528	1420	11	,	,	PUNCT
fnp-3528	1420	12	c.	c.	PROPN
fnp-3528	1420	13	c.	c.	PROPN
fnp-3528	1420	14	;	;	PUNCT
fnp-3528	1420	15	kuiatse	kuiatse	PROPN
fnp-3528	1420	16	,	,	PUNCT
fnp-3528	1420	17	i.	i.	NOUN
fnp-3528	1420	18	;	;	PUNCT
fnp-3528	1420	19	remaley	remaley	PROPN
fnp-3528	1420	20	,	,	PUNCT
fnp-3528	1420	21	a.	a.	NOUN
fnp-3528	1420	22	t.	t.	PROPN
fnp-3528	1420	23	;	;	PUNCT
fnp-3528	1420	24	bashir	bashir	PROPN
fnp-3528	1420	25	,	,	PUNCT
fnp-3528	1420	26	t.	t.	PROPN
fnp-3528	1420	27	;	;	PUNCT
fnp-3528	1420	28	vreys	vrey	NOUN
fnp-3528	1420	29	,	,	PUNCT
fnp-3528	1420	30	v.	v.	ADV
fnp-3528	1420	31	;	;	PUNCT
fnp-3528	1420	32	orlowski	orlowski	PROPN
fnp-3528	1420	33	,	,	PUNCT
fnp-3528	1420	34	r.	r.	PROPN
fnp-3528	1420	35	z.	z.	PROPN
fnp-3528	1421	1	the	the	DET
fnp-3528	1421	2	novel	novel	ADJ
fnp-3528	1421	3	anticancer	anticancer	NOUN
fnp-3528	1421	4	agent	agent	NOUN
fnp-3528	1421	5	jnj-26854165	jnj-26854165	NOUN
fnp-3528	1421	6	induces	induce	VERB
fnp-3528	1421	7	cell	cell	NOUN
fnp-3528	1421	8	death	death	NOUN
fnp-3528	1421	9	through	through	ADP
fnp-3528	1421	10	inhibition	inhibition	NOUN
fnp-3528	1421	11	of	of	ADP
fnp-3528	1421	12	cholesterol	cholesterol	NOUN
fnp-3528	1421	13	transport	transport	NOUN
fnp-3528	1421	14	and	and	CCONJ
fnp-3528	1421	15	degradation	degradation	NOUN
fnp-3528	1421	16	of	of	ADP
fnp-3528	1421	17	abca1	abca1	NOUN
fnp-3528	1421	18	.	.	PUNCT
fnp-3528	1422	1	j	j	PROPN
fnp-3528	1422	2	pharmacol	pharmacol	PROPN
fnp-3528	1422	3	exp	exp	NOUN
fnp-3528	1422	4	ther	ther	ADV
fnp-3528	1422	5	2013	2013	NUM
fnp-3528	1422	6	,	,	PUNCT
fnp-3528	1422	7	346	346	NUM
fnp-3528	1422	8	,	,	PUNCT
fnp-3528	1422	9	381	381	NUM
fnp-3528	1422	10	-	-	SYM
fnp-3528	1422	11	92	92	NUM
fnp-3528	1422	12	.	.	PUNCT
fnp-3528	1423	1	roberts	roberts	PROPN
fnp-3528	1423	2	,	,	PUNCT
fnp-3528	1423	3	a.	a.	NOUN
fnp-3528	1423	4	g.	g.	NOUN
fnp-3528	1423	5	the	the	DET
fnp-3528	1423	6	structure	structure	NOUN
fnp-3528	1423	7	and	and	CCONJ
fnp-3528	1423	8	mechanism	mechanism	NOUN
fnp-3528	1423	9	of	of	ADP
fnp-3528	1423	10	drug	drug	NOUN
fnp-3528	1423	11	transporters	transporter	NOUN
fnp-3528	1423	12	.	.	PUNCT
fnp-3528	1424	1	methods	method	NOUN
fnp-3528	1424	2	in	in	ADP
fnp-3528	1424	3	molecular	molecular	ADJ
fnp-3528	1424	4	biology	biology	NOUN
fnp-3528	1424	5	(	(	PUNCT
fnp-3528	1424	6	clifton	clifton	PROPN
fnp-3528	1424	7	,	,	PUNCT
fnp-3528	1424	8	n.j	n.j	PROPN
fnp-3528	1424	9	)	)	PUNCT
fnp-3528	1424	10	2021	2021	NUM
fnp-3528	1424	11	,	,	PUNCT
fnp-3528	1424	12	2342	2342	NUM
fnp-3528	1424	13	,	,	PUNCT
fnp-3528	1424	14	193	193	NUM
fnp-3528	1424	15	-	-	SYM
fnp-3528	1424	16	234	234	NUM
fnp-3528	1424	17	.	.	PUNCT
fnp-3528	1425	1	qian	qian	PROPN
fnp-3528	1425	2	,	,	PUNCT
fnp-3528	1425	3	h.	h.	PROPN
fnp-3528	1425	4	;	;	PUNCT
fnp-3528	1425	5	zhao	zhao	PROPN
fnp-3528	1425	6	,	,	PUNCT
fnp-3528	1425	7	x.	x.	PROPN
fnp-3528	1425	8	;	;	PUNCT
fnp-3528	1425	9	cao	cao	PROPN
fnp-3528	1425	10	,	,	PUNCT
fnp-3528	1425	11	p.	p.	NOUN
fnp-3528	1425	12	;	;	PUNCT
fnp-3528	1425	13	lei	lei	PROPN
fnp-3528	1425	14	,	,	PUNCT
fnp-3528	1425	15	j.	j.	PROPN
fnp-3528	1425	16	;	;	PUNCT
fnp-3528	1425	17	yan	yan	PROPN
fnp-3528	1425	18	,	,	PUNCT
fnp-3528	1425	19	n.	n.	PROPN
fnp-3528	1425	20	;	;	PUNCT
fnp-3528	1425	21	gong	gong	NOUN
fnp-3528	1425	22	,	,	PUNCT
fnp-3528	1425	23	x.	x.	NOUN
fnp-3528	1425	24	structure	structure	NOUN
fnp-3528	1425	25	of	of	ADP
fnp-3528	1425	26	the	the	DET
fnp-3528	1425	27	human	human	ADJ
fnp-3528	1425	28	lipid	lipid	NOUN
fnp-3528	1425	29	exporter	exporter	NOUN
fnp-3528	1425	30	abca1	abca1	NOUN
fnp-3528	1425	31	.	.	PUNCT
fnp-3528	1426	1	cell	cell	NOUN
fnp-3528	1426	2	2017	2017	NUM
fnp-3528	1426	3	,	,	PUNCT
fnp-3528	1426	4	169	169	NUM
fnp-3528	1426	5	,	,	PUNCT
fnp-3528	1426	6	1228	1228	NUM
fnp-3528	1426	7	-	-	SYM
fnp-3528	1426	8	1239	1239	NUM
fnp-3528	1426	9	e10	e10	NOUN
fnp-3528	1426	10	.	.	PUNCT
fnp-3528	1427	1	scortecci	scortecci	PROPN
fnp-3528	1427	2	,	,	PUNCT
fnp-3528	1427	3	j.	j.	PROPN
fnp-3528	1427	4	f.	f.	PROPN
fnp-3528	1427	5	;	;	PUNCT
fnp-3528	1427	6	molday	molday	PROPN
fnp-3528	1427	7	,	,	PUNCT
fnp-3528	1427	8	l.	l.	PROPN
fnp-3528	1427	9	l.	l.	PROPN
fnp-3528	1427	10	;	;	PUNCT
fnp-3528	1427	11	curtis	curtis	PROPN
fnp-3528	1427	12	,	,	PUNCT
fnp-3528	1427	13	s.	s.	PROPN
fnp-3528	1427	14	b.	b.	PROPN
fnp-3528	1427	15	;	;	PUNCT
fnp-3528	1427	16	garces	garces	PROPN
fnp-3528	1427	17	,	,	PUNCT
fnp-3528	1427	18	f.	f.	PROPN
fnp-3528	1427	19	a.	a.	PROPN
fnp-3528	1427	20	;	;	PUNCT
fnp-3528	1427	21	panwar	panwar	PROPN
fnp-3528	1427	22	,	,	PUNCT
fnp-3528	1427	23	p.	p.	NOUN
fnp-3528	1427	24	;	;	PUNCT
fnp-3528	1427	25	van	van	PROPN
fnp-3528	1427	26	petegem	petegem	PROPN
fnp-3528	1427	27	,	,	PUNCT
fnp-3528	1427	28	f.	f.	PROPN
fnp-3528	1427	29	;	;	PUNCT
fnp-3528	1427	30	molday	molday	PROPN
fnp-3528	1427	31	,	,	PUNCT
fnp-3528	1427	32	r.	r.	PROPN
fnp-3528	1427	33	s.	s.	PROPN
fnp-3528	1427	34	cryo	cryo	PROPN
fnp-3528	1427	35	-	-	PUNCT
fnp-3528	1427	36	em	em	PRON
fnp-3528	1427	37	structures	structure	NOUN
fnp-3528	1427	38	of	of	ADP
fnp-3528	1427	39	the	the	DET
fnp-3528	1427	40	abca4	abca4	PROPN
fnp-3528	1427	41	importer	importer	NOUN
fnp-3528	1427	42	reveal	reveal	NOUN
fnp-3528	1427	43	mechanisms	mechanism	NOUN
fnp-3528	1427	44	underlying	underlie	VERB
fnp-3528	1427	45	substrate	substrate	NOUN
fnp-3528	1427	46	binding	binding	ADJ
fnp-3528	1427	47	and	and	CCONJ
fnp-3528	1427	48	stargardt	stargardt	ADJ
fnp-3528	1427	49	disease	disease	NOUN
fnp-3528	1427	50	.	.	PUNCT
fnp-3528	1428	1	nat	nat	PROPN
fnp-3528	1428	2	commun	commun	PROPN
fnp-3528	1428	3	2021	2021	NUM
fnp-3528	1428	4	,	,	PUNCT
fnp-3528	1428	5	12	12	NUM
fnp-3528	1428	6	,	,	PUNCT
fnp-3528	1428	7	5902	5902	NUM
fnp-3528	1428	8	.	.	PUNCT
fnp-3528	1429	1	liu	liu	PROPN
fnp-3528	1429	2	,	,	PUNCT
fnp-3528	1429	3	f.	f.	PROPN
fnp-3528	1429	4	;	;	PUNCT
fnp-3528	1429	5	lee	lee	PROPN
fnp-3528	1429	6	,	,	PUNCT
fnp-3528	1429	7	j.	j.	PROPN
fnp-3528	1429	8	;	;	PUNCT
fnp-3528	1429	9	chen	chen	PROPN
fnp-3528	1429	10	,	,	PUNCT
fnp-3528	1429	11	j.	j.	PROPN
fnp-3528	1429	12	molecular	molecular	ADJ
fnp-3528	1429	13	structures	structure	NOUN
fnp-3528	1429	14	of	of	ADP
fnp-3528	1429	15	the	the	DET
fnp-3528	1429	16	eukaryotic	eukaryotic	ADJ
fnp-3528	1429	17	retinal	retinal	ADJ
fnp-3528	1429	18	importer	importer	NOUN
fnp-3528	1429	19	abca4	abca4	PROPN
fnp-3528	1429	20	.	.	PUNCT
fnp-3528	1430	1	elife	elife	NOUN
fnp-3528	1430	2	2021	2021	NUM
fnp-3528	1430	3	,	,	PUNCT
fnp-3528	1430	4	10	10	NUM
fnp-3528	1430	5	,	,	PUNCT
fnp-3528	1430	6	e63524	e63524	PROPN
fnp-3528	1430	7	.	.	PUNCT
fnp-3528	1430	8	xie	xie	PROPN
fnp-3528	1430	9	,	,	PUNCT
fnp-3528	1430	10	t.	t.	PROPN
fnp-3528	1430	11	;	;	PUNCT
fnp-3528	1430	12	zhang	zhang	PROPN
fnp-3528	1430	13	,	,	PUNCT
fnp-3528	1430	14	z.	z.	PROPN
fnp-3528	1430	15	;	;	PUNCT
fnp-3528	1430	16	fang	fang	PROPN
fnp-3528	1430	17	,	,	PUNCT
fnp-3528	1430	18	q.	q.	PROPN
fnp-3528	1430	19	;	;	PUNCT
fnp-3528	1430	20	du	du	PROPN
fnp-3528	1430	21	,	,	PUNCT
fnp-3528	1430	22	b.	b.	PROPN
fnp-3528	1430	23	;	;	PUNCT
fnp-3528	1430	24	gong	gong	PROPN
fnp-3528	1430	25	,	,	PUNCT
fnp-3528	1430	26	x.	x.	NOUN
fnp-3528	1430	27	structural	structural	ADJ
fnp-3528	1430	28	basis	basis	NOUN
fnp-3528	1430	29	of	of	ADP
fnp-3528	1430	30	substrate	substrate	NOUN
fnp-3528	1430	31	recognition	recognition	NOUN
fnp-3528	1430	32	and	and	CCONJ
fnp-3528	1430	33	translocation	translocation	NOUN
fnp-3528	1430	34	by	by	ADP
fnp-3528	1430	35	human	human	ADJ
fnp-3528	1430	36	abca4	abca4	PROPN
fnp-3528	1430	37	.	.	PUNCT
fnp-3528	1431	1	nat	nat	PROPN
fnp-3528	1431	2	commun	commun	PROPN
fnp-3528	1431	3	2021	2021	NUM
fnp-3528	1431	4	,	,	PUNCT
fnp-3528	1431	5	12	12	NUM
fnp-3528	1431	6	,	,	PUNCT
fnp-3528	1431	7	3853	3853	NUM
fnp-3528	1431	8	.	.	PUNCT
fnp-3528	1432	1	my	my	PRON
fnp-3528	1432	2	le	le	X
fnp-3528	1432	3	,	,	PUNCT
fnp-3528	1432	4	l.	l.	PROPN
fnp-3528	1432	5	t.	t.	PROPN
fnp-3528	1432	6	;	;	PUNCT
fnp-3528	1432	7	thompson	thompson	PROPN
fnp-3528	1432	8	,	,	PUNCT
fnp-3528	1432	9	j.	j.	PROPN
fnp-3528	1432	10	r.	r.	PROPN
fnp-3528	1432	11	;	;	PUNCT
fnp-3528	1432	12	aikawa	aikawa	PROPN
fnp-3528	1432	13	,	,	PUNCT
fnp-3528	1432	14	t.	t.	PROPN
fnp-3528	1432	15	;	;	PUNCT
fnp-3528	1432	16	kanikeyo	kanikeyo	PROPN
fnp-3528	1432	17	,	,	PUNCT
fnp-3528	1432	18	t.	t.	PROPN
fnp-3528	1432	19	;	;	PUNCT
fnp-3528	1432	20	alam	alam	PROPN
fnp-3528	1432	21	,	,	PUNCT
fnp-3528	1432	22	a.	a.	PROPN
fnp-3528	1432	23	cryo	cryo	PROPN
fnp-3528	1432	24	-	-	PUNCT
fnp-3528	1432	25	em	em	PROPN
fnp-3528	1432	26	structure	structure	NOUN
fnp-3528	1432	27	of	of	ADP
fnp-3528	1432	28	lipid	lipid	NOUN
fnp-3528	1432	29	embedded	embed	VERB
fnp-3528	1432	30	human	human	ADJ
fnp-3528	1432	31	abca7	abca7	NOUN
fnp-3528	1432	32	at	at	ADP
fnp-3528	1432	33	3.6å	3.6å	PROPN
fnp-3528	1432	34	resolution	resolution	NOUN
fnp-3528	1432	35	.	.	PUNCT
fnp-3528	1433	1	biorxiv	biorxiv	NOUN
fnp-3528	1433	2	2021	2021	NUM
fnp-3528	1433	3	,	,	PUNCT
fnp-3528	1433	4	2021.03.01.433448	2021.03.01.433448	PROPN
fnp-3528	1433	5	.	.	PUNCT
fnp-3528	1434	1	namasivayam	namasivayam	PROPN
fnp-3528	1434	2	,	,	PUNCT
fnp-3528	1434	3	v.	v.	PROPN
fnp-3528	1434	4	s.	s.	PROPN
fnp-3528	1434	5	,	,	PUNCT
fnp-3528	1434	6	k.	k.	PROPN
fnp-3528	1434	7	;	;	PUNCT
fnp-3528	1434	8	pahnke	pahnke	PROPN
fnp-3528	1434	9	,	,	PUNCT
fnp-3528	1434	10	j.	j.	PROPN
fnp-3528	1434	11	;	;	PUNCT
fnp-3528	1434	12	stefan	stefan	PROPN
fnp-3528	1434	13	,	,	PUNCT
fnp-3528	1434	14	s.	s.	PROPN
fnp-3528	1434	15	m.	m.	PROPN
fnp-3528	1434	16	.	.	PUNCT
fnp-3528	1435	1	binding	bind	VERB
fnp-3528	1435	2	mode	mode	NOUN
fnp-3528	1435	3	analysis	analysis	NOUN
fnp-3528	1435	4	of	of	ADP
fnp-3528	1435	5	pan	pan	NOUN
fnp-3528	1435	6	-	-	ADJ
fnp-3528	1435	7	abc	abc	ADJ
fnp-3528	1435	8	transporter	transporter	NOUN
fnp-3528	1435	9	inhibitors	inhibitor	NOUN
fnp-3528	1435	10	within	within	ADP
fnp-3528	1435	11	human	human	ADJ
fnp-3528	1435	12	abca7	abca7	NOUN
fnp-3528	1435	13	to	to	PART
fnp-3528	1435	14	target	target	VERB
fnp-3528	1435	15	alzheimer	alzheimer	PROPN
fnp-3528	1435	16	’s	’s	PART
fnp-3528	1435	17	disease	disease	NOUN
fnp-3528	1435	18	.	.	PUNCT
fnp-3528	1436	1	comput	comput	PROPN
fnp-3528	1436	2	struct	struct	VERB
fnp-3528	1436	3	biotechnol	biotechnol	ADJ
fnp-3528	1436	4	j	j	PROPN
fnp-3528	1436	5	2021	2021	NUM
fnp-3528	1436	6	,	,	PUNCT
fnp-3528	1436	7	19	19	NUM
fnp-3528	1436	8	,	,	PUNCT
fnp-3528	1436	9	6490	6490	NUM
fnp-3528	1436	10	-	-	SYM
fnp-3528	1436	11	6504	6504	NUM
fnp-3528	1436	12	.	.	PUNCT
fnp-3528	1437	1	alam	alam	PROPN
fnp-3528	1437	2	,	,	PUNCT
fnp-3528	1437	3	a.	a.	NOUN
fnp-3528	1437	4	;	;	PUNCT
fnp-3528	1437	5	kowal	kowal	PROPN
fnp-3528	1437	6	,	,	PUNCT
fnp-3528	1437	7	j.	j.	PROPN
fnp-3528	1437	8	;	;	PUNCT
fnp-3528	1437	9	broude	broude	VERB
fnp-3528	1437	10	,	,	PUNCT
fnp-3528	1437	11	e.	e.	PROPN
fnp-3528	1437	12	;	;	PUNCT
fnp-3528	1437	13	roninson	roninson	PROPN
fnp-3528	1437	14	,	,	PUNCT
fnp-3528	1437	15	i.	i.	NOUN
fnp-3528	1437	16	;	;	PUNCT
fnp-3528	1437	17	locher	locher	ADV
fnp-3528	1437	18	,	,	PUNCT
fnp-3528	1437	19	k.	k.	PROPN
fnp-3528	1438	1	p.	p.	PROPN
fnp-3528	1438	2	structural	structural	ADJ
fnp-3528	1438	3	insight	insight	NOUN
fnp-3528	1438	4	into	into	ADP
fnp-3528	1438	5	substrate	substrate	NOUN
fnp-3528	1438	6	and	and	CCONJ
fnp-3528	1438	7	inhibitor	inhibitor	NOUN
fnp-3528	1438	8	discrimination	discrimination	NOUN
fnp-3528	1438	9	by	by	ADP
fnp-3528	1438	10	human	human	ADJ
fnp-3528	1438	11	p	p	NOUN
fnp-3528	1438	12	-	-	PUNCT
fnp-3528	1438	13	glycoprotein	glycoprotein	NOUN
fnp-3528	1438	14	.	.	PUNCT
fnp-3528	1439	1	science	science	NOUN
fnp-3528	1439	2	2019	2019	NUM
fnp-3528	1439	3	,	,	PUNCT
fnp-3528	1439	4	363	363	NUM
fnp-3528	1439	5	,	,	PUNCT
fnp-3528	1439	6	753	753	NUM
fnp-3528	1439	7	-	-	SYM
fnp-3528	1439	8	6	6	NUM
fnp-3528	1439	9	.	.	PUNCT
fnp-3528	1440	1	fitzgerald	fitzgerald	PROPN
fnp-3528	1440	2	,	,	PUNCT
fnp-3528	1440	3	m.	m.	PROPN
fnp-3528	1440	4	l.	l.	PROPN
fnp-3528	1440	5	;	;	PUNCT
fnp-3528	1440	6	morris	morris	PROPN
fnp-3528	1440	7	,	,	PUNCT
fnp-3528	1440	8	a.	a.	PROPN
fnp-3528	1440	9	l.	l.	PROPN
fnp-3528	1440	10	;	;	PUNCT
fnp-3528	1440	11	rhee	rhee	PROPN
fnp-3528	1440	12	,	,	PUNCT
fnp-3528	1440	13	j.	j.	PROPN
fnp-3528	1440	14	s.	s.	PROPN
fnp-3528	1440	15	;	;	PUNCT
fnp-3528	1440	16	andersson	andersson	PROPN
fnp-3528	1440	17	,	,	PUNCT
fnp-3528	1440	18	l.	l.	PROPN
fnp-3528	1440	19	p.	p.	PROPN
fnp-3528	1440	20	;	;	PUNCT
fnp-3528	1440	21	mendez	mendez	PROPN
fnp-3528	1440	22	,	,	PUNCT
fnp-3528	1440	23	a.	a.	PROPN
fnp-3528	1440	24	j.	j.	PROPN
fnp-3528	1440	25	;	;	PUNCT
fnp-3528	1440	26	freeman	freeman	PROPN
fnp-3528	1440	27	,	,	PUNCT
fnp-3528	1440	28	m.	m.	NOUN
fnp-3528	1440	29	w.	w.	PROPN
fnp-3528	1440	30	naturally	naturally	ADV
fnp-3528	1440	31	occurring	occur	VERB
fnp-3528	1440	32	mutations	mutation	NOUN
fnp-3528	1440	33	in	in	ADP
fnp-3528	1440	34	the	the	DET
fnp-3528	1440	35	largest	large	ADJ
fnp-3528	1440	36	extracellular	extracellular	ADJ
fnp-3528	1440	37	loops	loop	NOUN
fnp-3528	1440	38	of	of	ADP
fnp-3528	1440	39	abca1	abca1	NOUN
fnp-3528	1440	40	can	can	AUX
fnp-3528	1440	41	disrupt	disrupt	VERB
fnp-3528	1440	42	its	its	PRON
fnp-3528	1440	43	direct	direct	ADJ
fnp-3528	1440	44	interaction	interaction	NOUN
fnp-3528	1440	45	with	with	ADP
fnp-3528	1440	46	apolipoprotein	apolipoprotein	ADJ
fnp-3528	1440	47	a	a	DET
fnp-3528	1440	48	-	-	PUNCT
fnp-3528	1440	49	i.	i.	NOUN
fnp-3528	1440	50	j	j	PROPN
fnp-3528	1440	51	biol	biol	PROPN
fnp-3528	1440	52	chem	chem	NOUN
fnp-3528	1440	53	2002	2002	NUM
fnp-3528	1440	54	,	,	PUNCT
fnp-3528	1440	55	277	277	NUM
fnp-3528	1440	56	,	,	PUNCT
fnp-3528	1440	57	33178	33178	NUM
fnp-3528	1440	58	-	-	SYM
fnp-3528	1440	59	87	87	NUM
fnp-3528	1440	60	.	.	PUNCT
fnp-3528	1441	1	lee	lee	PROPN
fnp-3528	1441	2	,	,	PUNCT
fnp-3528	1441	3	j.	j.	PROPN
fnp-3528	1441	4	y.	y.	PROPN
fnp-3528	1441	5	;	;	PUNCT
fnp-3528	1441	6	kinch	kinch	PROPN
fnp-3528	1441	7	,	,	PUNCT
fnp-3528	1441	8	l.	l.	PROPN
fnp-3528	1441	9	n.	n.	PROPN
fnp-3528	1441	10	;	;	PUNCT
fnp-3528	1441	11	borek	borek	PROPN
fnp-3528	1441	12	,	,	PUNCT
fnp-3528	1441	13	d.	d.	PROPN
fnp-3528	1441	14	m.	m.	PROPN
fnp-3528	1441	15	;	;	PUNCT
fnp-3528	1441	16	wang	wang	PROPN
fnp-3528	1441	17	,	,	PUNCT
fnp-3528	1441	18	j.	j.	PROPN
fnp-3528	1441	19	;	;	PUNCT
fnp-3528	1441	20	wang	wang	PROPN
fnp-3528	1441	21	,	,	PUNCT
fnp-3528	1441	22	j.	j.	PROPN
fnp-3528	1441	23	;	;	PUNCT
fnp-3528	1441	24	urbatsch	urbatsch	PROPN
fnp-3528	1441	25	,	,	PUNCT
fnp-3528	1441	26	i.	i.	PROPN
fnp-3528	1441	27	l.	l.	PROPN
fnp-3528	1441	28	;	;	PUNCT
fnp-3528	1441	29	xie	xie	PROPN
fnp-3528	1441	30	,	,	PUNCT
fnp-3528	1441	31	x.	x.	PROPN
fnp-3528	1441	32	s.	s.	PROPN
fnp-3528	1441	33	;	;	PUNCT
fnp-3528	1441	34	grishin	grishin	PROPN
fnp-3528	1441	35	,	,	PUNCT
fnp-3528	1441	36	n.	n.	PROPN
fnp-3528	1441	37	v.	v.	PROPN
fnp-3528	1441	38	;	;	PUNCT
fnp-3528	1441	39	cohen	cohen	PROPN
fnp-3528	1441	40	,	,	PUNCT
fnp-3528	1441	41	j.	j.	PROPN
fnp-3528	1441	42	c.	c.	PROPN
fnp-3528	1441	43	;	;	PUNCT
fnp-3528	1441	44	otwinowski	otwinowski	PROPN
fnp-3528	1441	45	,	,	PUNCT
fnp-3528	1441	46	z.	z.	PROPN
fnp-3528	1441	47	;	;	PUNCT
fnp-3528	1441	48	hobbs	hobbs	PROPN
fnp-3528	1441	49	,	,	PUNCT
fnp-3528	1441	50	h.	h.	PROPN
fnp-3528	1441	51	h.	h.	PROPN
fnp-3528	1441	52	;	;	PUNCT
fnp-3528	1441	53	rosenbaum	rosenbaum	PROPN
fnp-3528	1441	54	,	,	PUNCT
fnp-3528	1441	55	d.	d.	PROPN
fnp-3528	1441	56	m.	m.	PROPN
fnp-3528	1441	57	crystal	crystal	PROPN
fnp-3528	1441	58	structure	structure	NOUN
fnp-3528	1441	59	of	of	ADP
fnp-3528	1441	60	the	the	DET
fnp-3528	1441	61	human	human	ADJ
fnp-3528	1441	62	sterol	sterol	NOUN
fnp-3528	1441	63	transporter	transporter	NOUN
fnp-3528	1441	64	abcg5	abcg5	NOUN
fnp-3528	1441	65	/	/	SYM
fnp-3528	1441	66	abcg8	abcg8	NOUN
fnp-3528	1441	67	.	.	PUNCT
fnp-3528	1442	1	nature	nature	NOUN
fnp-3528	1442	2	2016	2016	NUM
fnp-3528	1442	3	,	,	PUNCT
fnp-3528	1442	4	533	533	NUM
fnp-3528	1442	5	,	,	PUNCT
fnp-3528	1442	6	561	561	NUM
fnp-3528	1442	7	-	-	SYM
fnp-3528	1442	8	4	4	NUM
fnp-3528	1442	9	.	.	X
fnp-3528	1442	10	adzhubei	adzhubei	NOUN
fnp-3528	1442	11	,	,	PUNCT
fnp-3528	1442	12	a.	a.	NOUN
fnp-3528	1442	13	a.	a.	PROPN
fnp-3528	1442	14	;	;	PUNCT
fnp-3528	1443	1	kulkarni	kulkarni	PROPN
fnp-3528	1443	2	,	,	PUNCT
fnp-3528	1443	3	a.	a.	PROPN
fnp-3528	1443	4	;	;	PUNCT
fnp-3528	1443	5	tolstova	tolstova	ADV
fnp-3528	1443	6	,	,	PUNCT
fnp-3528	1443	7	a.	a.	NOUN
fnp-3528	1443	8	p.	p.	NOUN
fnp-3528	1443	9	;	;	PUNCT
fnp-3528	1443	10	anashkina	anashkina	PROPN
fnp-3528	1443	11	,	,	PUNCT
fnp-3528	1443	12	a.	a.	NOUN
fnp-3528	1443	13	a.	a.	PROPN
fnp-3528	1443	14	;	;	PUNCT
fnp-3528	1443	15	sviridov	sviridov	PROPN
fnp-3528	1443	16	,	,	PUNCT
fnp-3528	1443	17	d.	d.	PROPN
fnp-3528	1443	18	;	;	PUNCT
fnp-3528	1443	19	makarov	makarov	PROPN
fnp-3528	1443	20	,	,	PUNCT
fnp-3528	1443	21	a.	a.	NOUN
fnp-3528	1443	22	a.	a.	NOUN
fnp-3528	1443	23	;	;	PUNCT
fnp-3528	1443	24	bukrinsky	bukrinsky	NOUN
fnp-3528	1443	25	,	,	PUNCT
fnp-3528	1443	26	m.	m.	NOUN
fnp-3528	1443	27	i.	i.	PROPN
fnp-3528	1443	28	direct	direct	PROPN
fnp-3528	1443	29	interaction	interaction	NOUN
fnp-3528	1443	30	between	between	ADP
fnp-3528	1443	31	abca1	abca1	PROPN
fnp-3528	1443	32	and	and	CCONJ
fnp-3528	1443	33	hiv-1	hiv-1	PUNCT
fnp-3528	1443	34	nef	nef	PROPN
fnp-3528	1443	35	:	:	PUNCT
fnp-3528	1443	36	molecular	molecular	ADJ
fnp-3528	1443	37	modeling	modeling	NOUN
fnp-3528	1443	38	and	and	CCONJ
fnp-3528	1443	39	virtual	virtual	ADJ
fnp-3528	1443	40	screening	screening	NOUN
fnp-3528	1443	41	for	for	ADP
fnp-3528	1443	42	inhibitors	inhibitor	NOUN
fnp-3528	1443	43	.	.	PUNCT
fnp-3528	1444	1	comput	comput	PROPN
fnp-3528	1444	2	struct	struct	VERB
fnp-3528	1444	3	biotechnol	biotechnol	ADJ
fnp-3528	1444	4	j	j	PROPN
fnp-3528	1444	5	2021	2021	NUM
fnp-3528	1444	6	,	,	PUNCT
fnp-3528	1444	7	19	19	NUM
fnp-3528	1444	8	,	,	PUNCT
fnp-3528	1444	9	3876	3876	NUM
fnp-3528	1444	10	-	-	SYM
fnp-3528	1444	11	84	84	NUM
fnp-3528	1444	12	.	.	PUNCT
fnp-3528	1445	1	krapf	krapf	PROPN
fnp-3528	1445	2	,	,	PUNCT
fnp-3528	1445	3	m.	m.	PROPN
fnp-3528	1445	4	k.	k.	PROPN
fnp-3528	1445	5	;	;	PUNCT
fnp-3528	1445	6	gallus	gallus	PROPN
fnp-3528	1445	7	,	,	PUNCT
fnp-3528	1445	8	j.	j.	PROPN
fnp-3528	1445	9	;	;	PUNCT
fnp-3528	1445	10	namasivayam	namasivayam	PROPN
fnp-3528	1445	11	,	,	PUNCT
fnp-3528	1445	12	v.	v.	PROPN
fnp-3528	1445	13	;	;	PUNCT
fnp-3528	1445	14	wiese	wiese	PROPN
fnp-3528	1445	15	,	,	PUNCT
fnp-3528	1445	16	m.	m.	NOUN
fnp-3528	1445	17	2,4,6	2,4,6	ADV
fnp-3528	1445	18	-	-	PUNCT
fnp-3528	1445	19	substituted	substitute	VERB
fnp-3528	1445	20	quinazolines	quinazoline	NOUN
fnp-3528	1445	21	with	with	ADP
fnp-3528	1445	22	extraordinary	extraordinary	ADJ
fnp-3528	1445	23	inhibitory	inhibitory	ADJ
fnp-3528	1445	24	potency	potency	NOUN
fnp-3528	1445	25	toward	toward	ADP
fnp-3528	1445	26	abcg2	abcg2	NOUN
fnp-3528	1445	27	.	.	PUNCT
fnp-3528	1446	1	j	j	PROPN
fnp-3528	1446	2	med	med	PROPN
fnp-3528	1446	3	chem	chem	NOUN
fnp-3528	1446	4	2018	2018	NUM
fnp-3528	1446	5	,	,	PUNCT
fnp-3528	1446	6	61	61	NUM
fnp-3528	1446	7	,	,	PUNCT
fnp-3528	1446	8	7952	7952	NUM
fnp-3528	1446	9	-	-	SYM
fnp-3528	1446	10	76	76	NUM
fnp-3528	1446	11	.	.	PUNCT
fnp-3528	1447	1	jackson	jackson	PROPN
fnp-3528	1447	2	,	,	PUNCT
fnp-3528	1447	3	s.	s.	PROPN
fnp-3528	1447	4	m.	m.	PROPN
fnp-3528	1447	5	;	;	PUNCT
fnp-3528	1447	6	manolaridis	manolaridi	NOUN
fnp-3528	1447	7	,	,	PUNCT
fnp-3528	1447	8	i.	i.	PROPN
fnp-3528	1447	9	;	;	PUNCT
fnp-3528	1447	10	kowal	kowal	PROPN
fnp-3528	1447	11	,	,	PUNCT
fnp-3528	1447	12	j.	j.	PROPN
fnp-3528	1447	13	;	;	PUNCT
fnp-3528	1447	14	zechner	zechner	NOUN
fnp-3528	1447	15	,	,	PUNCT
fnp-3528	1447	16	m.	m.	NOUN
fnp-3528	1447	17	;	;	PUNCT
fnp-3528	1447	18	taylor	taylor	PROPN
fnp-3528	1447	19	,	,	PUNCT
fnp-3528	1447	20	n.	n.	PROPN
fnp-3528	1447	21	m.	m.	PROPN
fnp-3528	1447	22	i.	i.	PROPN
fnp-3528	1447	23	;	;	PUNCT
fnp-3528	1447	24	bause	bause	NOUN
fnp-3528	1447	25	,	,	PUNCT
fnp-3528	1447	26	m.	m.	NOUN
fnp-3528	1447	27	;	;	PUNCT
fnp-3528	1447	28	bauer	bauer	PROPN
fnp-3528	1447	29	,	,	PUNCT
fnp-3528	1447	30	s.	s.	PROPN
fnp-3528	1447	31	;	;	PUNCT
fnp-3528	1447	32	bartholomaeus	bartholomaeus	NOUN
fnp-3528	1447	33	,	,	PUNCT
fnp-3528	1447	34	r.	r.	PROPN
fnp-3528	1447	35	;	;	PUNCT
fnp-3528	1447	36	bernhardt	bernhardt	PROPN
fnp-3528	1447	37	,	,	PUNCT
fnp-3528	1447	38	g.	g.	PROPN
fnp-3528	1447	39	;	;	PUNCT
fnp-3528	1447	40	koenig	koenig	PROPN
fnp-3528	1447	41	,	,	PUNCT
fnp-3528	1447	42	b.	b.	PROPN
fnp-3528	1447	43	;	;	PUNCT
fnp-3528	1447	44	buschauer	buschauer	PROPN
fnp-3528	1447	45	,	,	PUNCT
fnp-3528	1447	46	a.	a.	NOUN
fnp-3528	1447	47	;	;	PUNCT
fnp-3528	1447	48	stahlberg	stahlberg	PROPN
fnp-3528	1447	49	,	,	PUNCT
fnp-3528	1447	50	h.	h.	PROPN
fnp-3528	1447	51	;	;	PUNCT
fnp-3528	1447	52	altmann	altmann	PROPN
fnp-3528	1447	53	,	,	PUNCT
fnp-3528	1447	54	k.	k.	PROPN
fnp-3528	1447	55	h.	h.	PROPN
fnp-3528	1447	56	;	;	PUNCT
fnp-3528	1448	1	locher	locher	ADV
fnp-3528	1448	2	,	,	PUNCT
fnp-3528	1448	3	k.	k.	PROPN
fnp-3528	1449	1	p.	p.	PROPN
fnp-3528	1449	2	structural	structural	ADJ
fnp-3528	1449	3	basis	basis	NOUN
fnp-3528	1449	4	of	of	ADP
fnp-3528	1449	5	small	small	ADJ
fnp-3528	1449	6	-	-	PUNCT
fnp-3528	1449	7	molecule	molecule	NOUN
fnp-3528	1449	8	inhibition	inhibition	NOUN
fnp-3528	1449	9	of	of	ADP
fnp-3528	1449	10	human	human	ADJ
fnp-3528	1449	11	multidrug	multidrug	NOUN
fnp-3528	1449	12	transporter	transporter	NOUN
fnp-3528	1449	13	abcg2	abcg2	NOUN
fnp-3528	1449	14	.	.	PUNCT
fnp-3528	1450	1	nat	nat	PROPN
fnp-3528	1450	2	struct	struct	NOUN
fnp-3528	1450	3	mol	mol	ADP
fnp-3528	1450	4	biol	biol	PROPN
fnp-3528	1450	5	2018	2018	NUM
fnp-3528	1450	6	,	,	PUNCT
fnp-3528	1450	7	25	25	NUM
fnp-3528	1450	8	,	,	PUNCT
fnp-3528	1450	9	333	333	NUM
fnp-3528	1450	10	-	-	SYM
fnp-3528	1450	11	40	40	NUM
fnp-3528	1450	12	.	.	PUNCT
fnp-3528	1451	1	rarey	rarey	PROPN
fnp-3528	1451	2	,	,	PUNCT
fnp-3528	1451	3	m.	m.	NOUN
fnp-3528	1451	4	;	;	PUNCT
fnp-3528	1451	5	kramer	kramer	PROPN
fnp-3528	1451	6	,	,	PUNCT
fnp-3528	1451	7	b.	b.	PROPN
fnp-3528	1451	8	;	;	PUNCT
fnp-3528	1451	9	lengauer	lengauer	PROPN
fnp-3528	1451	10	,	,	PUNCT
fnp-3528	1451	11	t.	t.	PROPN
fnp-3528	1451	12	time	time	NOUN
fnp-3528	1451	13	-	-	PUNCT
fnp-3528	1451	14	efficient	efficient	ADJ
fnp-3528	1451	15	docking	docking	NOUN
fnp-3528	1451	16	of	of	ADP
fnp-3528	1451	17	flexible	flexible	ADJ
fnp-3528	1451	18	ligands	ligand	NOUN
fnp-3528	1451	19	into	into	ADP
fnp-3528	1451	20	active	active	ADJ
fnp-3528	1451	21	sites	site	NOUN
fnp-3528	1451	22	of	of	ADP
fnp-3528	1451	23	proteins	protein	NOUN
fnp-3528	1451	24	.	.	PUNCT
fnp-3528	1452	1	proc	proc	NOUN
fnp-3528	1452	2	int	int	PROPN
fnp-3528	1452	3	conf	conf	PROPN
fnp-3528	1452	4	intell	intell	PROPN
fnp-3528	1452	5	syst	syst	PROPN
fnp-3528	1452	6	mol	mol	ADP
fnp-3528	1452	7	biol	biol	PROPN
fnp-3528	1452	8	1995	1995	NUM
fnp-3528	1452	9	,	,	PUNCT
fnp-3528	1452	10	3	3	NUM
fnp-3528	1452	11	,	,	PUNCT
fnp-3528	1452	12	300	300	NUM
fnp-3528	1452	13	-	-	SYM
fnp-3528	1452	14	8	8	NUM
fnp-3528	1452	15	.	.	PUNCT
fnp-3528	1453	1	ni	ni	PROPN
fnp-3528	1453	2	,	,	PUNCT
fnp-3528	1453	3	z.	z.	PROPN
fnp-3528	1453	4	;	;	PUNCT
fnp-3528	1453	5	bikadi	bikadi	NOUN
fnp-3528	1453	6	,	,	PUNCT
fnp-3528	1453	7	z.	z.	PROPN
fnp-3528	1453	8	;	;	PUNCT
fnp-3528	1453	9	cai	cai	X
fnp-3528	1453	10	,	,	PUNCT
fnp-3528	1453	11	x.	x.	PROPN
fnp-3528	1453	12	;	;	PUNCT
fnp-3528	1453	13	rosenberg	rosenberg	PROPN
fnp-3528	1453	14	,	,	PUNCT
fnp-3528	1453	15	m.	m.	PROPN
fnp-3528	1453	16	f.	f.	PROPN
fnp-3528	1453	17	;	;	PUNCT
fnp-3528	1453	18	mao	mao	PROPN
fnp-3528	1453	19	,	,	PUNCT
fnp-3528	1453	20	q.	q.	PROPN
fnp-3528	1453	21	transmembrane	transmembrane	NOUN
fnp-3528	1453	22	helices	helix	NOUN
fnp-3528	1453	23	1	1	NUM
fnp-3528	1453	24	and	and	CCONJ
fnp-3528	1453	25	6	6	NUM
fnp-3528	1453	26	of	of	ADP
fnp-3528	1453	27	the	the	DET
fnp-3528	1453	28	human	human	ADJ
fnp-3528	1453	29	breast	breast	NOUN
fnp-3528	1453	30	cancer	cancer	NOUN
fnp-3528	1453	31	resistance	resistance	NOUN
fnp-3528	1453	32	protein	protein	NOUN
fnp-3528	1453	33	(	(	PUNCT
fnp-3528	1453	34	bcrp	bcrp	ADV
fnp-3528	1453	35	/	/	SYM
fnp-3528	1453	36	abcg2	abcg2	NOUN
fnp-3528	1453	37	):	):	PUNCT
fnp-3528	1453	38	identification	identification	NOUN
fnp-3528	1453	39	of	of	ADP
fnp-3528	1453	40	polar	polar	ADJ
fnp-3528	1453	41	residues	residue	NOUN
fnp-3528	1453	42	important	important	ADJ
fnp-3528	1453	43	for	for	ADP
fnp-3528	1453	44	drug	drug	NOUN
fnp-3528	1453	45	transport	transport	NOUN
fnp-3528	1453	46	.	.	PUNCT
fnp-3528	1454	1	am	be	AUX
fnp-3528	1454	2	j	j	PROPN
fnp-3528	1454	3	physiol	physiol	PROPN
fnp-3528	1454	4	cell	cell	PROPN
fnp-3528	1454	5	physiol	physiol	PROPN
fnp-3528	1454	6	2010	2010	NUM
fnp-3528	1454	7	,	,	PUNCT
fnp-3528	1454	8	299	299	NUM
fnp-3528	1454	9	,	,	PUNCT
fnp-3528	1454	10	c1100	c1100	NOUN
fnp-3528	1454	11	-	-	PUNCT
fnp-3528	1454	12	9	9	NUM
fnp-3528	1454	13	.	.	PUNCT
fnp-3528	1455	1	tamura	tamura	PROPN
fnp-3528	1455	2	,	,	PUNCT
fnp-3528	1455	3	a.	a.	PROPN
fnp-3528	1455	4	;	;	PUNCT
fnp-3528	1455	5	watanabe	watanabe	PROPN
fnp-3528	1455	6	,	,	PUNCT
fnp-3528	1455	7	m.	m.	NOUN
fnp-3528	1455	8	;	;	PUNCT
fnp-3528	1455	9	saito	saito	PROPN
fnp-3528	1455	10	,	,	PUNCT
fnp-3528	1455	11	h.	h.	PROPN
fnp-3528	1455	12	;	;	PUNCT
fnp-3528	1455	13	nakagawa	nakagawa	PROPN
fnp-3528	1455	14	,	,	PUNCT
fnp-3528	1455	15	h.	h.	PROPN
fnp-3528	1455	16	;	;	PUNCT
fnp-3528	1455	17	kamachi	kamachi	PROPN
fnp-3528	1455	18	,	,	PUNCT
fnp-3528	1455	19	t.	t.	PROPN
fnp-3528	1455	20	;	;	PUNCT
fnp-3528	1455	21	okura	okura	NOUN
fnp-3528	1455	22	,	,	PUNCT
fnp-3528	1455	23	i.	i.	PROPN
fnp-3528	1455	24	;	;	PUNCT
fnp-3528	1455	25	ishikawa	ishikawa	PROPN
fnp-3528	1455	26	,	,	PUNCT
fnp-3528	1455	27	t.	t.	NOUN
fnp-3528	1455	28	functional	functional	ADJ
fnp-3528	1455	29	validation	validation	NOUN
fnp-3528	1455	30	of	of	ADP
fnp-3528	1455	31	the	the	DET
fnp-3528	1455	32	genetic	genetic	ADJ
fnp-3528	1455	33	polymorphisms	polymorphism	NOUN
fnp-3528	1455	34	of	of	ADP
fnp-3528	1455	35	human	human	PROPN
fnp-3528	1455	36	atp	atp	PROPN
fnp-3528	1455	37	-	-	PUNCT
fnp-3528	1455	38	binding	bind	VERB
fnp-3528	1455	39	cassette	cassette	NOUN
fnp-3528	1455	40	(	(	PUNCT
fnp-3528	1455	41	abc	abc	PROPN
fnp-3528	1455	42	)	)	PUNCT
fnp-3528	1455	43	transporter	transporter	NOUN
fnp-3528	1455	44	abcg2	abcg2	NOUN
fnp-3528	1455	45	:	:	PUNCT
fnp-3528	1455	46	identification	identification	NOUN
fnp-3528	1455	47	of	of	ADP
fnp-3528	1455	48	alleles	allele	NOUN
fnp-3528	1455	49	that	that	PRON
fnp-3528	1455	50	are	be	AUX
fnp-3528	1455	51	defective	defective	ADJ
fnp-3528	1455	52	in	in	ADP
fnp-3528	1455	53	porphyrin	porphyrin	NOUN
fnp-3528	1455	54	transport	transport	NOUN
fnp-3528	1455	55	.	.	PUNCT
fnp-3528	1456	1	mol	mol	ADP
fnp-3528	1456	2	pharmacol	pharmacol	PROPN
fnp-3528	1456	3	2006	2006	NUM
fnp-3528	1456	4	,	,	PUNCT
fnp-3528	1456	5	70	70	NUM
fnp-3528	1456	6	,	,	PUNCT
fnp-3528	1456	7	287	287	NUM
fnp-3528	1456	8	-	-	SYM
fnp-3528	1456	9	96	96	NUM
fnp-3528	1456	10	.	.	PUNCT
fnp-3528	1457	1	ozvegy	ozvegy	PROPN
fnp-3528	1457	2	,	,	PUNCT
fnp-3528	1457	3	c.	c.	PROPN
fnp-3528	1457	4	;	;	PUNCT
fnp-3528	1457	5	varadi	varadi	NOUN
fnp-3528	1457	6	,	,	PUNCT
fnp-3528	1457	7	a.	a.	NOUN
fnp-3528	1457	8	;	;	PUNCT
fnp-3528	1457	9	sarkadi	sarkadi	PROPN
fnp-3528	1457	10	,	,	PUNCT
fnp-3528	1457	11	b.	b.	PROPN
fnp-3528	1457	12	characterization	characterization	NOUN
fnp-3528	1457	13	of	of	ADP
fnp-3528	1457	14	drug	drug	NOUN
fnp-3528	1457	15	transport	transport	NOUN
fnp-3528	1457	16	,	,	PUNCT
fnp-3528	1457	17	atp	atp	NOUN
fnp-3528	1457	18	hydrolysis	hydrolysis	NOUN
fnp-3528	1457	19	,	,	PUNCT
fnp-3528	1457	20	and	and	CCONJ
fnp-3528	1457	21	nucleotide	nucleotide	NOUN
fnp-3528	1457	22	trapping	trap	VERB
fnp-3528	1457	23	by	by	ADP
fnp-3528	1457	24	the	the	DET
fnp-3528	1457	25	human	human	PROPN
fnp-3528	1457	26	abcg2	abcg2	PROPN
fnp-3528	1457	27	multidrug	multidrug	NOUN
fnp-3528	1457	28	transporter	transporter	NOUN
fnp-3528	1457	29	.	.	PUNCT
fnp-3528	1458	1	modulation	modulation	NOUN
fnp-3528	1458	2	of	of	ADP
fnp-3528	1458	3	substrate	substrate	NOUN
fnp-3528	1458	4	specificity	specificity	NOUN
fnp-3528	1458	5	by	by	ADP
fnp-3528	1458	6	a	a	DET
fnp-3528	1458	7	point	point	NOUN
fnp-3528	1458	8	mutation	mutation	NOUN
fnp-3528	1458	9	.	.	PUNCT
fnp-3528	1459	1	j	j	PROPN
fnp-3528	1459	2	biol	biol	PROPN
fnp-3528	1459	3	chem	chem	NOUN
fnp-3528	1459	4	2002	2002	NUM
fnp-3528	1459	5	,	,	PUNCT
fnp-3528	1459	6	277	277	NUM
fnp-3528	1459	7	,	,	PUNCT
fnp-3528	1459	8	47980	47980	NUM
fnp-3528	1459	9	-	-	SYM
fnp-3528	1459	10	90	90	NUM
fnp-3528	1459	11	.	.	PUNCT
fnp-3528	1460	1	volk	volk	PROPN
fnp-3528	1460	2	,	,	PUNCT
fnp-3528	1460	3	e.	e.	PROPN
fnp-3528	1460	4	l.	l.	PROPN
fnp-3528	1460	5	;	;	PUNCT
fnp-3528	1460	6	farley	farley	PROPN
fnp-3528	1460	7	,	,	PUNCT
fnp-3528	1460	8	k.	k.	PROPN
fnp-3528	1460	9	m.	m.	PROPN
fnp-3528	1460	10	;	;	PUNCT
fnp-3528	1460	11	wu	wu	PROPN
fnp-3528	1460	12	,	,	PUNCT
fnp-3528	1460	13	y.	y.	PROPN
fnp-3528	1460	14	;	;	PUNCT
fnp-3528	1460	15	li	li	PROPN
fnp-3528	1460	16	,	,	PUNCT
fnp-3528	1460	17	f.	f.	PROPN
fnp-3528	1460	18	;	;	PUNCT
fnp-3528	1460	19	robey	robey	PROPN
fnp-3528	1460	20	,	,	PUNCT
fnp-3528	1460	21	r.	r.	PROPN
fnp-3528	1460	22	w.	w.	PROPN
fnp-3528	1460	23	;	;	PUNCT
fnp-3528	1460	24	schneider	schneider	PROPN
fnp-3528	1460	25	,	,	PUNCT
fnp-3528	1460	26	e.	e.	PROPN
fnp-3528	1460	27	overexpression	overexpression	NOUN
fnp-3528	1460	28	of	of	ADP
fnp-3528	1460	29	wild	wild	ADJ
fnp-3528	1460	30	-	-	PUNCT
fnp-3528	1460	31	type	type	NOUN
fnp-3528	1460	32	breast	breast	NOUN
fnp-3528	1460	33	cancer	cancer	NOUN
fnp-3528	1460	34	resistance	resistance	NOUN
fnp-3528	1460	35	protein	protein	NOUN
fnp-3528	1460	36	mediates	mediate	NOUN
fnp-3528	1460	37	methotrexate	methotrexate	VERB
fnp-3528	1460	38	resistance	resistance	NOUN
fnp-3528	1460	39	.	.	PUNCT
fnp-3528	1461	1	cancer	cancer	NOUN
fnp-3528	1461	2	res	re	NOUN
fnp-3528	1461	3	2002	2002	NUM
fnp-3528	1461	4	,	,	PUNCT
fnp-3528	1461	5	62	62	NUM
fnp-3528	1461	6	,	,	PUNCT
fnp-3528	1461	7	5035	5035	NUM
fnp-3528	1461	8	-	-	SYM
fnp-3528	1461	9	40	40	NUM
fnp-3528	1462	1	.	.	PUNCT
fnp-3528	1462	2	honjo	honjo	PROPN
fnp-3528	1462	3	,	,	PUNCT
fnp-3528	1462	4	y.	y.	PROPN
fnp-3528	1462	5	;	;	PUNCT
fnp-3528	1462	6	hrycyna	hrycyna	NOUN
fnp-3528	1462	7	,	,	PUNCT
fnp-3528	1462	8	c.	c.	PROPN
fnp-3528	1462	9	a.	a.	PROPN
fnp-3528	1462	10	;	;	PUNCT
fnp-3528	1462	11	yan	yan	PROPN
fnp-3528	1462	12	,	,	PUNCT
fnp-3528	1462	13	q.	q.	PROPN
fnp-3528	1462	14	w.	w.	PROPN
fnp-3528	1462	15	;	;	PUNCT
fnp-3528	1462	16	medina	medina	PROPN
fnp-3528	1462	17	-	-	PUNCT
fnp-3528	1462	18	perez	perez	PROPN
fnp-3528	1462	19	,	,	PUNCT
fnp-3528	1462	20	w.	w.	PROPN
fnp-3528	1462	21	y.	y.	PROPN
fnp-3528	1462	22	;	;	PUNCT
fnp-3528	1462	23	robey	robey	PROPN
fnp-3528	1462	24	,	,	PUNCT
fnp-3528	1462	25	r.	r.	PROPN
fnp-3528	1462	26	w.	w.	PROPN
fnp-3528	1462	27	;	;	PUNCT
fnp-3528	1462	28	van	van	PROPN
fnp-3528	1462	29	de	de	PROPN
fnp-3528	1462	30	laar	laar	PROPN
fnp-3528	1462	31	,	,	PUNCT
fnp-3528	1462	32	a.	a.	NOUN
fnp-3528	1462	33	;	;	PUNCT
fnp-3528	1462	34	litman	litman	NOUN
fnp-3528	1462	35	,	,	PUNCT
fnp-3528	1462	36	t.	t.	PROPN
fnp-3528	1462	37	;	;	PUNCT
fnp-3528	1462	38	dean	dean	PROPN
fnp-3528	1462	39	,	,	PUNCT
fnp-3528	1462	40	m.	m.	NOUN
fnp-3528	1462	41	;	;	PUNCT
fnp-3528	1462	42	bates	bate	NOUN
fnp-3528	1462	43	,	,	PUNCT
fnp-3528	1462	44	s.	s.	PROPN
fnp-3528	1462	45	e.	e.	PROPN
fnp-3528	1462	46	acquired	acquire	VERB
fnp-3528	1462	47	mutations	mutation	NOUN
fnp-3528	1462	48	in	in	ADP
fnp-3528	1462	49	the	the	DET
fnp-3528	1462	50	mxr	mxr	PROPN
fnp-3528	1462	51	/	/	SYM
fnp-3528	1462	52	bcrp	bcrp	PROPN
fnp-3528	1462	53	/	/	SYM
fnp-3528	1462	54	abcp	abcp	NOUN
fnp-3528	1462	55	gene	gene	NOUN
fnp-3528	1462	56	alter	alter	NOUN
fnp-3528	1462	57	substrate	substrate	NOUN
fnp-3528	1462	58	specificity	specificity	NOUN
fnp-3528	1462	59	in	in	ADP
fnp-3528	1462	60	mxr	mxr	PROPN
fnp-3528	1462	61	/	/	SYM
fnp-3528	1462	62	bcrp	bcrp	PROPN
fnp-3528	1462	63	/	/	SYM
fnp-3528	1462	64	abcp	abcp	NOUN
fnp-3528	1462	65	-	-	PUNCT
fnp-3528	1462	66	overexpressing	overexpresse	VERB
fnp-3528	1462	67	cells	cell	NOUN
fnp-3528	1462	68	.	.	PUNCT
fnp-3528	1463	1	cancer	cancer	NOUN
fnp-3528	1463	2	res	re	NOUN
fnp-3528	1463	3	2001	2001	NUM
fnp-3528	1463	4	,	,	PUNCT
fnp-3528	1463	5	61	61	NUM
fnp-3528	1463	6	,	,	PUNCT
fnp-3528	1463	7	6635	6635	NUM
fnp-3528	1463	8	-	-	SYM
fnp-3528	1463	9	9	9	NUM
fnp-3528	1463	10	.	.	PUNCT
fnp-3528	1463	11	silbermann	silbermann	PROPN
fnp-3528	1463	12	,	,	PUNCT
fnp-3528	1463	13	k.	k.	PROPN
fnp-3528	1463	14	;	;	PUNCT
fnp-3528	1463	15	li	li	PROPN
fnp-3528	1463	16	,	,	PUNCT
fnp-3528	1463	17	j.	j.	PROPN
fnp-3528	1463	18	;	;	PUNCT
fnp-3528	1463	19	namasivayam	namasivayam	PROPN
fnp-3528	1463	20	,	,	PUNCT
fnp-3528	1463	21	v.	v.	PROPN
fnp-3528	1463	22	;	;	PUNCT
fnp-3528	1463	23	stefan	stefan	PROPN
fnp-3528	1463	24	,	,	PUNCT
fnp-3528	1463	25	s.	s.	PROPN
fnp-3528	1463	26	m.	m.	PROPN
fnp-3528	1463	27	;	;	PUNCT
fnp-3528	1463	28	wiese	wiese	PROPN
fnp-3528	1463	29	,	,	PUNCT
fnp-3528	1463	30	m.	m.	NOUN
fnp-3528	1463	31	rational	rational	ADJ
fnp-3528	1463	32	drug	drug	NOUN
fnp-3528	1463	33	design	design	NOUN
fnp-3528	1463	34	of	of	ADP
fnp-3528	1463	35	6	6	NUM
fnp-3528	1463	36	-	-	PUNCT
fnp-3528	1463	37	substituted	substitute	VERB
fnp-3528	1463	38	4	4	NUM
fnp-3528	1463	39	-	-	PUNCT
fnp-3528	1463	40	anilino-2	anilino-2	NOUN
fnp-3528	1463	41	-	-	PUNCT
fnp-3528	1463	42	phenylpyrimidines	phenylpyrimidine	NOUN
fnp-3528	1463	43	for	for	ADP
fnp-3528	1463	44	exploration	exploration	NOUN
fnp-3528	1463	45	of	of	ADP
fnp-3528	1463	46	novel	novel	NOUN
fnp-3528	1463	47	abcg2	abcg2	NOUN
fnp-3528	1463	48	binding	bind	VERB
fnp-3528	1463	49	site	site	NOUN
fnp-3528	1463	50	.	.	PUNCT
fnp-3528	1464	1	eur	eur	PROPN
fnp-3528	1464	2	j	j	PROPN
fnp-3528	1464	3	med	med	PROPN
fnp-3528	1464	4	chem	chem	NOUN
fnp-3528	1464	5	2021	2021	NUM
fnp-3528	1464	6	,	,	PUNCT
fnp-3528	1464	7	212	212	NUM
fnp-3528	1464	8	,	,	PUNCT
fnp-3528	1464	9	113045	113045	NUM
fnp-3528	1464	10	.	.	PUNCT
fnp-3528	1464	11	silbermann	silbermann	PROPN
fnp-3528	1464	12	,	,	PUNCT
fnp-3528	1464	13	k.	k.	PROPN
fnp-3528	1464	14	;	;	PUNCT
fnp-3528	1464	15	li	li	PROPN
fnp-3528	1464	16	,	,	PUNCT
fnp-3528	1464	17	j.	j.	PROPN
fnp-3528	1464	18	;	;	PUNCT
fnp-3528	1464	19	namasivayam	namasivayam	PROPN
fnp-3528	1464	20	,	,	PUNCT
fnp-3528	1464	21	v.	v.	ADV
fnp-3528	1464	22	;	;	PUNCT
fnp-3528	1464	23	baltes	balte	NOUN
fnp-3528	1464	24	,	,	PUNCT
fnp-3528	1464	25	f.	f.	PROPN
fnp-3528	1464	26	;	;	PUNCT
fnp-3528	1464	27	bendas	bendas	PROPN
fnp-3528	1464	28	,	,	PUNCT
fnp-3528	1464	29	g.	g.	PROPN
fnp-3528	1464	30	;	;	PUNCT
fnp-3528	1464	31	stefan	stefan	PROPN
fnp-3528	1464	32	,	,	PUNCT
fnp-3528	1464	33	s.	s.	PROPN
fnp-3528	1464	34	m.	m.	PROPN
fnp-3528	1464	35	;	;	PUNCT
fnp-3528	1464	36	wiese	wiese	PROPN
fnp-3528	1464	37	,	,	PUNCT
fnp-3528	1464	38	m.	m.	NOUN
fnp-3528	1464	39	superior	superior	ADJ
fnp-3528	1464	40	pyrimidine	pyrimidine	NOUN
fnp-3528	1464	41	derivatives	derivative	NOUN
fnp-3528	1464	42	as	as	ADP
fnp-3528	1464	43	selective	selective	ADJ
fnp-3528	1464	44	abcg2	abcg2	NOUN
fnp-3528	1464	45	inhibitors	inhibitor	NOUN
fnp-3528	1464	46	and	and	CCONJ
fnp-3528	1464	47	broad	broad	ADJ
fnp-3528	1464	48	-	-	PUNCT
fnp-3528	1464	49	spectrum	spectrum	NOUN
fnp-3528	1464	50	abcb1	abcb1	NOUN
fnp-3528	1464	51	,	,	PUNCT
fnp-3528	1464	52	abcc1	abcc1	PROPN
fnp-3528	1464	53	,	,	PUNCT
fnp-3528	1464	54	and	and	CCONJ
fnp-3528	1464	55	abcg2	abcg2	NOUN
fnp-3528	1464	56	antagonists	antagonist	NOUN
fnp-3528	1464	57	.	.	PUNCT
fnp-3528	1465	1	j	j	PROPN
fnp-3528	1465	2	med	med	PROPN
fnp-3528	1465	3	chem	chem	NOUN
fnp-3528	1465	4	2020	2020	NUM
fnp-3528	1465	5	,	,	PUNCT
fnp-3528	1465	6	63	63	NUM
fnp-3528	1465	7	,	,	PUNCT
fnp-3528	1465	8	10412	10412	NUM
fnp-3528	1465	9	-	-	SYM
fnp-3528	1465	10	32	32	NUM
fnp-3528	1465	11	.	.	PUNCT
fnp-3528	1466	1	kim	kim	PROPN
fnp-3528	1466	2	,	,	PUNCT
fnp-3528	1466	3	s.	s.	PROPN
fnp-3528	1466	4	;	;	PUNCT
fnp-3528	1466	5	thiessen	thiessen	PROPN
fnp-3528	1466	6	,	,	PUNCT
fnp-3528	1466	7	p.	p.	NOUN
fnp-3528	1466	8	a.	a.	NOUN
fnp-3528	1466	9	;	;	PUNCT
fnp-3528	1466	10	bolton	bolton	PROPN
fnp-3528	1466	11	,	,	PUNCT
fnp-3528	1466	12	e.	e.	PROPN
fnp-3528	1466	13	e.	e.	PROPN
fnp-3528	1466	14	;	;	PUNCT
fnp-3528	1466	15	chen	chen	PROPN
fnp-3528	1466	16	,	,	PUNCT
fnp-3528	1466	17	j.	j.	PROPN
fnp-3528	1466	18	;	;	PUNCT
fnp-3528	1466	19	fu	fu	PROPN
fnp-3528	1466	20	,	,	PUNCT
fnp-3528	1466	21	g.	g.	PROPN
fnp-3528	1466	22	;	;	PUNCT
fnp-3528	1466	23	gindulyte	gindulyte	PROPN
fnp-3528	1466	24	,	,	PUNCT
fnp-3528	1466	25	a.	a.	PROPN
fnp-3528	1466	26	;	;	PUNCT
fnp-3528	1466	27	han	han	PROPN
fnp-3528	1466	28	,	,	PUNCT
fnp-3528	1466	29	l.	l.	PROPN
fnp-3528	1466	30	;	;	PUNCT
fnp-3528	1466	31	he	he	PRON
fnp-3528	1466	32	,	,	PUNCT
fnp-3528	1466	33	j.	j.	PROPN
fnp-3528	1466	34	;	;	PUNCT
fnp-3528	1466	35	he	he	PRON
fnp-3528	1466	36	,	,	PUNCT
fnp-3528	1466	37	s.	s.	PROPN
fnp-3528	1466	38	;	;	PUNCT
fnp-3528	1466	39	shoemaker	shoemaker	PROPN
fnp-3528	1466	40	,	,	PUNCT
fnp-3528	1466	41	b.	b.	PROPN
fnp-3528	1466	42	a.	a.	PROPN
fnp-3528	1466	43	;	;	PUNCT
fnp-3528	1466	44	wang	wang	PROPN
fnp-3528	1466	45	,	,	PUNCT
fnp-3528	1466	46	j.	j.	PROPN
fnp-3528	1466	47	;	;	PUNCT
fnp-3528	1466	48	yu	yu	PROPN
fnp-3528	1466	49	,	,	PUNCT
fnp-3528	1466	50	b.	b.	PROPN
fnp-3528	1466	51	;	;	PUNCT
fnp-3528	1466	52	zhang	zhang	PROPN
fnp-3528	1466	53	,	,	PUNCT
fnp-3528	1466	54	j.	j.	PROPN
fnp-3528	1466	55	;	;	PUNCT
fnp-3528	1466	56	bryant	bryant	PROPN
fnp-3528	1466	57	,	,	PUNCT
fnp-3528	1466	58	s.	s.	PROPN
fnp-3528	1466	59	h.	h.	PROPN
fnp-3528	1466	60	pubchem	pubchem	PROPN
fnp-3528	1466	61	substance	substance	NOUN
fnp-3528	1466	62	and	and	CCONJ
fnp-3528	1466	63	compound	compound	NOUN
fnp-3528	1466	64	databases	database	NOUN
fnp-3528	1466	65	.	.	PUNCT
fnp-3528	1467	1	nucleic	nucleic	ADJ
fnp-3528	1467	2	acids	acid	NOUN
fnp-3528	1467	3	res	re	NOUN
fnp-3528	1467	4	2016	2016	NUM
fnp-3528	1467	5	,	,	PUNCT
fnp-3528	1467	6	44	44	NUM
fnp-3528	1467	7	,	,	PUNCT
fnp-3528	1467	8	d1202	d1202	PROPN
fnp-3528	1467	9	-	-	PUNCT
fnp-3528	1467	10	13	13	NUM
fnp-3528	1467	11	.	.	PUNCT
fnp-3528	1468	1	rogers	rogers	PROPN
fnp-3528	1468	2	,	,	PUNCT
fnp-3528	1468	3	d.	d.	PROPN
fnp-3528	1468	4	;	;	PUNCT
fnp-3528	1468	5	hahn	hahn	PROPN
fnp-3528	1468	6	,	,	PUNCT
fnp-3528	1468	7	m.	m.	NOUN
fnp-3528	1468	8	extended	extend	VERB
fnp-3528	1468	9	-	-	PUNCT
fnp-3528	1468	10	connectivity	connectivity	NOUN
fnp-3528	1468	11	fingerprints	fingerprint	NOUN
fnp-3528	1468	12	.	.	PUNCT
fnp-3528	1469	1	j	j	PROPN
fnp-3528	1469	2	chem	chem	PROPN
fnp-3528	1469	3	inf	inf	PROPN
fnp-3528	1469	4	model	model	NOUN
fnp-3528	1469	5	2010	2010	NUM
fnp-3528	1469	6	,	,	PUNCT
fnp-3528	1469	7	50	50	NUM
fnp-3528	1469	8	,	,	PUNCT
fnp-3528	1469	9	742	742	NUM
fnp-3528	1469	10	-	-	SYM
fnp-3528	1469	11	54	54	NUM
fnp-3528	1469	12	.	.	PUNCT
fnp-3528	1470	1	bender	bender	PROPN
fnp-3528	1470	2	,	,	PUNCT
fnp-3528	1470	3	a.	a.	NOUN
fnp-3528	1470	4	;	;	PUNCT
fnp-3528	1470	5	mussa	mussa	ADJ
fnp-3528	1470	6	,	,	PUNCT
fnp-3528	1470	7	h.	h.	PROPN
fnp-3528	1470	8	y.	y.	PROPN
fnp-3528	1470	9	;	;	PUNCT
fnp-3528	1470	10	glen	glen	PROPN
fnp-3528	1470	11	,	,	PUNCT
fnp-3528	1470	12	r.	r.	PROPN
fnp-3528	1470	13	c.	c.	PROPN
fnp-3528	1470	14	;	;	PUNCT
fnp-3528	1470	15	reiling	reile	VERB
fnp-3528	1470	16	,	,	PUNCT
fnp-3528	1470	17	s.	s.	PROPN
fnp-3528	1470	18	molecular	molecular	ADJ
fnp-3528	1470	19	similarity	similarity	NOUN
fnp-3528	1470	20	searching	search	VERB
fnp-3528	1470	21	using	use	VERB
fnp-3528	1470	22	atom	atom	NOUN
fnp-3528	1470	23	environments	environment	NOUN
fnp-3528	1470	24	,	,	PUNCT
fnp-3528	1470	25	information	information	NOUN
fnp-3528	1470	26	-	-	PUNCT
fnp-3528	1470	27	based	base	VERB
fnp-3528	1470	28	feature	feature	NOUN
fnp-3528	1470	29	selection	selection	NOUN
fnp-3528	1470	30	,	,	PUNCT
fnp-3528	1470	31	and	and	CCONJ
fnp-3528	1470	32	a	a	DET
fnp-3528	1470	33	naive	naive	ADJ
fnp-3528	1470	34	bayesian	bayesian	NOUN
fnp-3528	1470	35	classifier	classifier	NOUN
fnp-3528	1470	36	.	.	PUNCT
fnp-3528	1471	1	j	j	PROPN
fnp-3528	1471	2	chem	chem	PROPN
fnp-3528	1471	3	inf	inf	PROPN
fnp-3528	1471	4	comput	comput	VERB
fnp-3528	1471	5	sci	sci	PROPN
fnp-3528	1471	6	2004	2004	NUM
fnp-3528	1471	7	,	,	PUNCT
fnp-3528	1471	8	44	44	NUM
fnp-3528	1471	9	,	,	PUNCT
fnp-3528	1471	10	170	170	NUM
fnp-3528	1471	11	-	-	SYM
fnp-3528	1471	12	8	8	NUM
fnp-3528	1471	13	.	.	PUNCT
fnp-3528	1471	14	silbermann	silbermann	PROPN
fnp-3528	1471	15	,	,	PUNCT
fnp-3528	1471	16	k.	k.	PROPN
fnp-3528	1471	17	;	;	PUNCT
fnp-3528	1471	18	stefan	stefan	PROPN
fnp-3528	1471	19	,	,	PUNCT
fnp-3528	1471	20	s.	s.	PROPN
fnp-3528	1471	21	m.	m.	PROPN
fnp-3528	1471	22	;	;	PUNCT
fnp-3528	1471	23	elshawadfy	elshawadfy	PROPN
fnp-3528	1471	24	,	,	PUNCT
fnp-3528	1471	25	r.	r.	PROPN
fnp-3528	1471	26	;	;	PUNCT
fnp-3528	1471	27	namasivayam	namasivayam	PROPN
fnp-3528	1471	28	,	,	PUNCT
fnp-3528	1471	29	v.	v.	PROPN
fnp-3528	1471	30	;	;	PUNCT
fnp-3528	1471	31	wiese	wiese	PROPN
fnp-3528	1471	32	,	,	PUNCT
fnp-3528	1471	33	m.	m.	NOUN
fnp-3528	1471	34	identification	identification	NOUN
fnp-3528	1471	35	of	of	ADP
fnp-3528	1471	36	thienopyrimidine	thienopyrimidine	NOUN
fnp-3528	1471	37	scaffold	scaffold	NOUN
fnp-3528	1471	38	as	as	ADP
fnp-3528	1471	39	an	an	DET
fnp-3528	1471	40	inhibitor	inhibitor	NOUN
fnp-3528	1471	41	of	of	ADP
fnp-3528	1471	42	the	the	DET
fnp-3528	1471	43	abc	abc	PROPN
fnp-3528	1471	44	transport	transport	NOUN
fnp-3528	1471	45	protein	protein	NOUN
fnp-3528	1471	46	abcc1	abcc1	PROPN
fnp-3528	1471	47	(	(	PUNCT
fnp-3528	1471	48	mrp1	mrp1	PROPN
fnp-3528	1471	49	)	)	PUNCT
fnp-3528	1471	50	and	and	CCONJ
fnp-3528	1471	51	related	relate	VERB
fnp-3528	1471	52	transporters	transporter	NOUN
fnp-3528	1471	53	using	use	VERB
fnp-3528	1471	54	a	a	DET
fnp-3528	1471	55	combined	combine	VERB
fnp-3528	1471	56	virtual	virtual	ADJ
fnp-3528	1471	57	screening	screening	NOUN
fnp-3528	1471	58	approach	approach	NOUN
fnp-3528	1471	59	.	.	PUNCT
fnp-3528	1472	1	j	j	PROPN
fnp-3528	1472	2	med	med	PROPN
fnp-3528	1472	3	chem	chem	NOUN
fnp-3528	1472	4	2019	2019	NUM
fnp-3528	1472	5	,	,	PUNCT
fnp-3528	1472	6	62	62	NUM
fnp-3528	1472	7	,	,	PUNCT
fnp-3528	1472	8	4383	4383	NUM
fnp-3528	1472	9	-	-	SYM
fnp-3528	1472	10	400	400	NUM
fnp-3528	1472	11	.	.	PUNCT
fnp-3528	1473	1	danish	danish	PROPN
fnp-3528	1473	2	,	,	PUNCT
fnp-3528	1473	3	a.	a.	NOUN
fnp-3528	1473	4	;	;	PUNCT
fnp-3528	1473	5	namasivayam	namasivayam	PROPN
fnp-3528	1473	6	,	,	PUNCT
fnp-3528	1473	7	v.	v.	PROPN
fnp-3528	1473	8	;	;	PUNCT
fnp-3528	1473	9	schiedel	schiedel	PROPN
fnp-3528	1473	10	,	,	PUNCT
fnp-3528	1473	11	a.	a.	PROPN
fnp-3528	1473	12	c.	c.	PROPN
fnp-3528	1473	13	;	;	PUNCT
fnp-3528	1473	14	muller	muller	NOUN
fnp-3528	1473	15	,	,	PUNCT
fnp-3528	1473	16	c.	c.	PROPN
fnp-3528	1473	17	e.	e.	PROPN
fnp-3528	1473	18	interaction	interaction	NOUN
fnp-3528	1473	19	of	of	ADP
fnp-3528	1473	20	approved	approve	VERB
fnp-3528	1473	21	drugs	drug	NOUN
fnp-3528	1473	22	with	with	ADP
fnp-3528	1473	23	synaptic	synaptic	ADJ
fnp-3528	1473	24	vesicle	vesicle	NOUN
fnp-3528	1473	25	protein	protein	NOUN
fnp-3528	1473	26	2a	2a	NUM
fnp-3528	1473	27	.	.	PUNCT
fnp-3528	1474	1	arch	arch	ADJ
fnp-3528	1474	2	pharm	pharm	PROPN
fnp-3528	1474	3	(	(	PUNCT
fnp-3528	1474	4	weinheim	weinheim	PROPN
fnp-3528	1474	5	)	)	PUNCT
fnp-3528	1474	6	2017	2017	NUM
fnp-3528	1474	7	,	,	PUNCT
fnp-3528	1474	8	350	350	NUM
fnp-3528	1474	9	.	.	PUNCT
fnp-3528	1474	10	namasivayam	namasivayam	PROPN
fnp-3528	1474	11	,	,	PUNCT
fnp-3528	1474	12	v.	v.	PROPN
fnp-3528	1474	13	s.	s.	PROPN
fnp-3528	1474	14	,	,	PUNCT
fnp-3528	1474	15	k.	k.	PROPN
fnp-3528	1474	16	;	;	PUNCT
fnp-3528	1474	17	pahnke	pahnke	PROPN
fnp-3528	1474	18	,	,	PUNCT
fnp-3528	1474	19	j.	j.	PROPN
fnp-3528	1474	20	;	;	PUNCT
fnp-3528	1474	21	wiese	wiese	PROPN
fnp-3528	1474	22	,	,	PUNCT
fnp-3528	1474	23	m.	m.	NOUN
fnp-3528	1474	24	;	;	PUNCT
fnp-3528	1474	25	stefan	stefan	PROPN
fnp-3528	1474	26	,	,	PUNCT
fnp-3528	1474	27	s.	s.	PROPN
fnp-3528	1474	28	m.	m.	PROPN
fnp-3528	1474	29	feature	feature	NOUN
fnp-3528	1474	30	-	-	PUNCT
fnp-3528	1474	31	driven	drive	VERB
fnp-3528	1474	32	pattern	pattern	NOUN
fnp-3528	1474	33	analysis	analysis	NOUN
fnp-3528	1474	34	for	for	ADP
fnp-3528	1474	35	multitarget	multitarget	NOUN
fnp-3528	1474	36	modulator	modulator	NOUN
fnp-3528	1474	37	landscapes	landscape	NOUN
fnp-3528	1474	38	.	.	PUNCT
fnp-3528	1475	1	bioinformatics	bioinformatic	NOUN
fnp-3528	1475	2	2021	2021	NUM
fnp-3528	1475	3	,	,	PUNCT
fnp-3528	1475	4	https://www.doi.org/10.1093/bioinformatics/btab832	https://www.doi.org/10.1093/bioinformatics/btab832	PROPN
fnp-3528	1475	5	lee	lee	PROPN
fnp-3528	1475	6	,	,	PUNCT
fnp-3528	1475	7	y.	y.	PROPN
fnp-3528	1475	8	m.	m.	PROPN
fnp-3528	1475	9	;	;	PUNCT
fnp-3528	1475	10	venkataraman	venkataraman	NOUN
fnp-3528	1475	11	,	,	PUNCT
fnp-3528	1475	12	k.	k.	PROPN
fnp-3528	1475	13	;	;	PUNCT
fnp-3528	1475	14	hwang	hwang	PROPN
fnp-3528	1475	15	,	,	PUNCT
fnp-3528	1475	16	s.	s.	PROPN
fnp-3528	1475	17	i.	i.	PROPN
fnp-3528	1475	18	;	;	PUNCT
fnp-3528	1475	19	han	han	PROPN
fnp-3528	1475	20	,	,	PUNCT
fnp-3528	1475	21	d.	d.	PROPN
fnp-3528	1475	22	k.	k.	PROPN
fnp-3528	1475	23	;	;	PUNCT
fnp-3528	1475	24	hla	hla	PROPN
fnp-3528	1475	25	,	,	PUNCT
fnp-3528	1475	26	t.	t.	X
fnp-3528	1475	27	a	a	DET
fnp-3528	1475	28	novel	novel	ADJ
fnp-3528	1475	29	method	method	NOUN
fnp-3528	1475	30	to	to	PART
fnp-3528	1475	31	quantify	quantify	VERB
fnp-3528	1475	32	sphingosine	sphingosine	NOUN
fnp-3528	1475	33	1	1	NUM
fnp-3528	1475	34	-	-	NOUN
fnp-3528	1475	35	phosphate	phosphate	NOUN
fnp-3528	1475	36	by	by	ADP
fnp-3528	1475	37	immobilized	immobilized	ADJ
fnp-3528	1475	38	metal	metal	NOUN
fnp-3528	1475	39	affinity	affinity	NOUN
fnp-3528	1475	40	chromatography	chromatography	NOUN
fnp-3528	1475	41	(	(	PUNCT
fnp-3528	1475	42	imac	imac	PROPN
fnp-3528	1475	43	)	)	PUNCT
fnp-3528	1475	44	.	.	PUNCT
fnp-3528	1475	45	prostaglandins	prostaglandin	VERB
fnp-3528	1475	46	other	other	ADJ
fnp-3528	1475	47	lipid	lipid	NOUN
fnp-3528	1475	48	mediat	mediat	PROPN
fnp-3528	1475	49	2007	2007	NUM
fnp-3528	1475	50	,	,	PUNCT
fnp-3528	1475	51	84	84	NUM
fnp-3528	1475	52	,	,	PUNCT
fnp-3528	1475	53	154	154	NUM
fnp-3528	1475	54	-	-	SYM
fnp-3528	1475	55	62	62	NUM
fnp-3528	1475	56	.	.	PUNCT
fnp-3528	1476	1	oram	oram	PROPN
fnp-3528	1476	2	,	,	PUNCT
fnp-3528	1476	3	j.	j.	PROPN
fnp-3528	1476	4	f.	f.	PROPN
fnp-3528	1476	5	;	;	PUNCT
fnp-3528	1476	6	vaughan	vaughan	PROPN
fnp-3528	1476	7	,	,	PUNCT
fnp-3528	1476	8	a.	a.	NOUN
fnp-3528	1476	9	m.	m.	NOUN
fnp-3528	1476	10	;	;	PUNCT
fnp-3528	1476	11	stocker	stocker	PROPN
fnp-3528	1476	12	,	,	PUNCT
fnp-3528	1476	13	r.	r.	PROPN
fnp-3528	1476	14	atp	atp	PROPN
fnp-3528	1476	15	-	-	PUNCT
fnp-3528	1476	16	binding	bind	VERB
fnp-3528	1476	17	cassette	cassette	NOUN
fnp-3528	1476	18	transporter	transporter	NOUN
fnp-3528	1476	19	a1	a1	NOUN
fnp-3528	1476	20	mediates	mediate	NOUN
fnp-3528	1476	21	cellular	cellular	ADJ
fnp-3528	1476	22	secretion	secretion	NOUN
fnp-3528	1476	23	of	of	ADP
fnp-3528	1476	24	alpha	alpha	NOUN
fnp-3528	1476	25	-	-	PUNCT
fnp-3528	1476	26	tocopherol	tocopherol	NOUN
fnp-3528	1476	27	.	.	PUNCT
fnp-3528	1477	1	j	j	PROPN
fnp-3528	1477	2	biol	biol	PROPN
fnp-3528	1477	3	chem	chem	NOUN
fnp-3528	1477	4	2001	2001	NUM
fnp-3528	1477	5	,	,	PUNCT
fnp-3528	1477	6	276	276	NUM
fnp-3528	1477	7	,	,	PUNCT
fnp-3528	1477	8	39898	39898	NUM
fnp-3528	1477	9	-	-	SYM
fnp-3528	1477	10	902	902	NUM
fnp-3528	1477	11	.	.	PUNCT
fnp-3528	1478	1	haller	haller	PROPN
fnp-3528	1478	2	,	,	PUNCT
fnp-3528	1478	3	j.	j.	PROPN
fnp-3528	1478	4	f.	f.	PROPN
fnp-3528	1478	5	;	;	PUNCT
fnp-3528	1478	6	cavallaro	cavallaro	NOUN
fnp-3528	1478	7	,	,	PUNCT
fnp-3528	1478	8	p.	p.	PROPN
fnp-3528	1478	9	;	;	PUNCT
fnp-3528	1478	10	hernandez	hernandez	PROPN
fnp-3528	1478	11	,	,	PUNCT
fnp-3528	1478	12	n.	n.	PROPN
fnp-3528	1478	13	j.	j.	PROPN
fnp-3528	1478	14	;	;	PUNCT
fnp-3528	1478	15	dolat	dolat	PROPN
fnp-3528	1478	16	,	,	PUNCT
fnp-3528	1478	17	l.	l.	PROPN
fnp-3528	1478	18	;	;	PUNCT
fnp-3528	1478	19	soscia	soscia	PROPN
fnp-3528	1478	20	,	,	PUNCT
fnp-3528	1478	21	s.	s.	PROPN
fnp-3528	1478	22	j.	j.	PROPN
fnp-3528	1478	23	;	;	PUNCT
fnp-3528	1478	24	welti	welti	PROPN
fnp-3528	1478	25	,	,	PUNCT
fnp-3528	1478	26	r.	r.	PROPN
fnp-3528	1478	27	;	;	PUNCT
fnp-3528	1478	28	grabowski	grabowski	PROPN
fnp-3528	1478	29	,	,	PUNCT
fnp-3528	1478	30	g.	g.	PROPN
fnp-3528	1478	31	a.	a.	PROPN
fnp-3528	1478	32	;	;	PUNCT
fnp-3528	1478	33	fitzgerald	fitzgerald	PROPN
fnp-3528	1478	34	,	,	PUNCT
fnp-3528	1478	35	m.	m.	PROPN
fnp-3528	1478	36	l.	l.	PROPN
fnp-3528	1478	37	;	;	PUNCT
fnp-3528	1478	38	freeman	freeman	PROPN
fnp-3528	1478	39	,	,	PUNCT
fnp-3528	1478	40	m.	m.	PROPN
fnp-3528	1478	41	w.	w.	PROPN
fnp-3528	1478	42	endogenous	endogenous	VERB
fnp-3528	1478	43	beta	beta	NOUN
fnp-3528	1478	44	-	-	PUNCT
fnp-3528	1478	45	glucocerebrosidase	glucocerebrosidase	NOUN
fnp-3528	1478	46	activity	activity	NOUN
fnp-3528	1478	47	in	in	ADP
fnp-3528	1478	48	abca12(-)/(-)epidermis	abca12(-)/(-)epidermis	PROPN
fnp-3528	1478	49	elevates	elevate	VERB
fnp-3528	1478	50	ceramide	ceramide	NOUN
fnp-3528	1478	51	levels	level	NOUN
fnp-3528	1478	52	after	after	ADP
fnp-3528	1478	53	topical	topical	ADJ
fnp-3528	1478	54	lipid	lipid	NOUN
fnp-3528	1478	55	application	application	NOUN
fnp-3528	1478	56	but	but	CCONJ
fnp-3528	1478	57	does	do	AUX
fnp-3528	1478	58	not	not	PART
fnp-3528	1478	59	restore	restore	VERB
fnp-3528	1478	60	barrier	barrier	NOUN
fnp-3528	1478	61	function	function	NOUN
fnp-3528	1478	62	.	.	PUNCT
fnp-3528	1479	1	j	j	PROPN
fnp-3528	1479	2	lipid	lipid	PROPN
fnp-3528	1479	3	res	re	NOUN
fnp-3528	1479	4	2014	2014	NUM
fnp-3528	1479	5	,	,	PUNCT
fnp-3528	1479	6	55	55	NUM
fnp-3528	1479	7	,	,	PUNCT
fnp-3528	1479	8	493	493	NUM
fnp-3528	1479	9	-	-	SYM
fnp-3528	1479	10	503	503	NUM
fnp-3528	1479	11	.	.	PUNCT
fnp-3528	1480	1	reboul	reboul	PROPN
fnp-3528	1480	2	,	,	PUNCT
fnp-3528	1480	3	e.	e.	PROPN
fnp-3528	1480	4	;	;	PUNCT
fnp-3528	1480	5	dyka	dyka	PROPN
fnp-3528	1480	6	,	,	PUNCT
fnp-3528	1480	7	f.	f.	PROPN
fnp-3528	1480	8	m.	m.	PROPN
fnp-3528	1480	9	;	;	PUNCT
fnp-3528	1480	10	quazi	quazi	PROPN
fnp-3528	1480	11	,	,	PUNCT
fnp-3528	1480	12	f.	f.	PROPN
fnp-3528	1480	13	;	;	PUNCT
fnp-3528	1480	14	molday	molday	PROPN
fnp-3528	1480	15	,	,	PUNCT
fnp-3528	1480	16	r.	r.	PROPN
fnp-3528	1480	17	s.	s.	PROPN
fnp-3528	1480	18	cholesterol	cholesterol	PROPN
fnp-3528	1480	19	transport	transport	NOUN
fnp-3528	1480	20	via	via	ADP
fnp-3528	1480	21	abca1	abca1	NOUN
fnp-3528	1480	22	:	:	PUNCT
fnp-3528	1480	23	new	new	ADJ
fnp-3528	1480	24	insights	insight	NOUN
fnp-3528	1480	25	from	from	ADP
fnp-3528	1480	26	solid	solid	ADJ
fnp-3528	1480	27	-	-	PUNCT
fnp-3528	1480	28	phase	phase	NOUN
fnp-3528	1480	29	binding	bind	VERB
fnp-3528	1480	30	assay	assay	NOUN
fnp-3528	1480	31	.	.	PUNCT
fnp-3528	1481	1	biochim	biochim	NOUN
fnp-3528	1481	2	2013	2013	NUM
fnp-3528	1481	3	,	,	PUNCT
fnp-3528	1481	4	95	95	NUM
fnp-3528	1481	5	,	,	PUNCT
fnp-3528	1481	6	957	957	NUM
fnp-3528	1481	7	-	-	SYM
fnp-3528	1481	8	61	61	NUM
fnp-3528	1481	9	.	.	PUNCT
fnp-3528	1482	1	beljanski	beljanski	PROPN
fnp-3528	1482	2	,	,	PUNCT
fnp-3528	1482	3	v.	v.	PROPN
fnp-3528	1482	4	;	;	PUNCT
fnp-3528	1482	5	soulika	soulika	PROPN
fnp-3528	1482	6	,	,	PUNCT
fnp-3528	1482	7	a.	a.	PROPN
fnp-3528	1482	8	;	;	PUNCT
fnp-3528	1482	9	tucker	tucker	PROPN
fnp-3528	1482	10	,	,	PUNCT
fnp-3528	1482	11	j.	j.	PROPN
fnp-3528	1482	12	m.	m.	PROPN
fnp-3528	1482	13	;	;	PUNCT
fnp-3528	1482	14	townsend	townsend	PROPN
fnp-3528	1482	15	,	,	PUNCT
fnp-3528	1482	16	d.	d.	PROPN
fnp-3528	1482	17	m.	m.	PROPN
fnp-3528	1482	18	;	;	PUNCT
fnp-3528	1482	19	davis	davis	PROPN
fnp-3528	1482	20	,	,	PUNCT
fnp-3528	1482	21	w.	w.	PROPN
fnp-3528	1482	22	,	,	PUNCT
fnp-3528	1482	23	jr	jr	PROPN
fnp-3528	1482	24	.	.	PROPN
fnp-3528	1482	25	;	;	PUNCT
fnp-3528	1482	26	tew	tew	PROPN
fnp-3528	1482	27	,	,	PUNCT
fnp-3528	1482	28	k.	k.	PROPN
fnp-3528	1482	29	d.	d.	PROPN
fnp-3528	1482	30	characterization	characterization	NOUN
fnp-3528	1482	31	of	of	ADP
fnp-3528	1482	32	the	the	DET
fnp-3528	1482	33	atpase	atpase	PROPN
fnp-3528	1482	34	activity	activity	NOUN
fnp-3528	1482	35	of	of	ADP
fnp-3528	1482	36	human	human	PROPN
fnp-3528	1482	37	atp	atp	PROPN
fnp-3528	1482	38	-	-	PUNCT
fnp-3528	1482	39	binding	bind	VERB
fnp-3528	1482	40	cassette	cassette	NOUN
fnp-3528	1482	41	transporter-2	transporter-2	NUM
fnp-3528	1482	42	(	(	PUNCT
fnp-3528	1482	43	abca2	abca2	PROPN
fnp-3528	1482	44	)	)	PUNCT
fnp-3528	1482	45	.	.	PUNCT
fnp-3528	1483	1	in	in	ADP
fnp-3528	1483	2	vivo	vivo	PROPN
fnp-3528	1483	3	(	(	PUNCT
fnp-3528	1483	4	athens	athens	PROPN
fnp-3528	1483	5	,	,	PUNCT
fnp-3528	1483	6	greece	greece	PROPN
fnp-3528	1483	7	)	)	PUNCT
fnp-3528	1483	8	2005	2005	NUM
fnp-3528	1483	9	,	,	PUNCT
fnp-3528	1483	10	19	19	NUM
fnp-3528	1483	11	,	,	PUNCT
fnp-3528	1483	12	657	657	NUM
fnp-3528	1483	13	-	-	SYM
fnp-3528	1483	14	60	60	NUM
fnp-3528	1483	15	.	.	PUNCT
fnp-3528	1484	1	tsybovsky	tsybovsky	PROPN
fnp-3528	1484	2	,	,	PUNCT
fnp-3528	1484	3	y.	y.	PROPN
fnp-3528	1484	4	;	;	PUNCT
fnp-3528	1484	5	wang	wang	PROPN
fnp-3528	1484	6	,	,	PUNCT
fnp-3528	1484	7	b.	b.	PROPN
fnp-3528	1484	8	;	;	PUNCT
fnp-3528	1484	9	quazi	quazi	PROPN
fnp-3528	1484	10	,	,	PUNCT
fnp-3528	1484	11	f.	f.	PROPN
fnp-3528	1484	12	;	;	PUNCT
fnp-3528	1484	13	molday	molday	PROPN
fnp-3528	1484	14	,	,	PUNCT
fnp-3528	1484	15	r.	r.	PROPN
fnp-3528	1484	16	s.	s.	PROPN
fnp-3528	1484	17	;	;	PUNCT
fnp-3528	1484	18	palczewski	palczewski	PROPN
fnp-3528	1484	19	,	,	PUNCT
fnp-3528	1484	20	k.	k.	PROPN
fnp-3528	1484	21	posttranslational	posttranslational	ADJ
fnp-3528	1484	22	modifications	modification	NOUN
fnp-3528	1484	23	of	of	ADP
fnp-3528	1484	24	the	the	DET
fnp-3528	1484	25	photoreceptor	photoreceptor	NOUN
fnp-3528	1484	26	-	-	PUNCT
fnp-3528	1484	27	specific	specific	ADJ
fnp-3528	1484	28	abc	abc	NOUN
fnp-3528	1484	29	transporter	transporter	NOUN
fnp-3528	1484	30	abca4	abca4	PROPN
fnp-3528	1484	31	.	.	PUNCT
fnp-3528	1485	1	biochem	biochem	PROPN
fnp-3528	1485	2	2011	2011	NUM
fnp-3528	1485	3	,	,	PUNCT
fnp-3528	1485	4	50	50	NUM
fnp-3528	1485	5	,	,	PUNCT
fnp-3528	1485	6	6855	6855	NUM
fnp-3528	1485	7	-	-	SYM
fnp-3528	1485	8	66	66	NUM
fnp-3528	1485	9	.	.	PUNCT
fnp-3528	1486	1	zhong	zhong	PROPN
fnp-3528	1486	2	,	,	PUNCT
fnp-3528	1486	3	m.	m.	NOUN
fnp-3528	1486	4	;	;	PUNCT
fnp-3528	1486	5	molday	molday	PROPN
fnp-3528	1486	6	,	,	PUNCT
fnp-3528	1486	7	l.	l.	PROPN
fnp-3528	1486	8	l.	l.	PROPN
fnp-3528	1486	9	;	;	PUNCT
fnp-3528	1486	10	molday	molday	PROPN
fnp-3528	1486	11	,	,	PUNCT
fnp-3528	1486	12	r.	r.	PROPN
fnp-3528	1486	13	s.	s.	PROPN
fnp-3528	1486	14	role	role	NOUN
fnp-3528	1486	15	of	of	ADP
fnp-3528	1486	16	the	the	DET
fnp-3528	1486	17	c	c	PROPN
fnp-3528	1486	18	terminus	terminus	NOUN
fnp-3528	1486	19	of	of	ADP
fnp-3528	1486	20	the	the	DET
fnp-3528	1486	21	photoreceptor	photoreceptor	NOUN
fnp-3528	1486	22	abca4	abca4	VERB
fnp-3528	1486	23	transporter	transporter	NOUN
fnp-3528	1486	24	in	in	ADP
fnp-3528	1486	25	protein	protein	NOUN
fnp-3528	1486	26	folding	folding	NOUN
fnp-3528	1486	27	,	,	PUNCT
fnp-3528	1486	28	function	function	NOUN
fnp-3528	1486	29	,	,	PUNCT
fnp-3528	1486	30	and	and	CCONJ
fnp-3528	1486	31	retinal	retinal	ADJ
fnp-3528	1486	32	degenerative	degenerative	ADJ
fnp-3528	1486	33	diseases	disease	NOUN
fnp-3528	1486	34	.	.	PUNCT
fnp-3528	1487	1	j	j	PROPN
fnp-3528	1487	2	biol	biol	PROPN
fnp-3528	1487	3	chem	chem	NOUN
fnp-3528	1487	4	2009	2009	NUM
fnp-3528	1487	5	,	,	PUNCT
fnp-3528	1487	6	284	284	NUM
fnp-3528	1487	7	,	,	PUNCT
fnp-3528	1487	8	3640	3640	NUM
fnp-3528	1487	9	-	-	SYM
fnp-3528	1487	10	9	9	NUM
fnp-3528	1487	11	.	.	PUNCT
fnp-3528	1487	12	petry	petry	PROPN
fnp-3528	1487	13	,	,	PUNCT
fnp-3528	1487	14	f.	f.	PROPN
fnp-3528	1487	15	;	;	PUNCT
fnp-3528	1487	16	ritz	ritz	PROPN
fnp-3528	1487	17	,	,	PUNCT
fnp-3528	1487	18	v.	v.	PROPN
fnp-3528	1487	19	;	;	PUNCT
fnp-3528	1487	20	meineke	meineke	ADJ
fnp-3528	1487	21	,	,	PUNCT
fnp-3528	1487	22	c.	c.	PROPN
fnp-3528	1487	23	;	;	PUNCT
fnp-3528	1487	24	middel	middel	PROPN
fnp-3528	1487	25	,	,	PUNCT
fnp-3528	1487	26	p.	p.	NOUN
fnp-3528	1487	27	;	;	PUNCT
fnp-3528	1487	28	kietzmann	kietzmann	PROPN
fnp-3528	1487	29	,	,	PUNCT
fnp-3528	1487	30	t.	t.	PROPN
fnp-3528	1487	31	;	;	PUNCT
fnp-3528	1487	32	schmitz	schmitz	PROPN
fnp-3528	1487	33	-	-	PUNCT
fnp-3528	1487	34	salue	salue	PROPN
fnp-3528	1487	35	,	,	PUNCT
fnp-3528	1487	36	c.	c.	PROPN
fnp-3528	1487	37	;	;	PUNCT
fnp-3528	1487	38	hirsch	hirsch	PROPN
fnp-3528	1487	39	-	-	PUNCT
fnp-3528	1487	40	ernst	ernst	PROPN
fnp-3528	1487	41	,	,	PUNCT
fnp-3528	1487	42	k.	k.	PROPN
fnp-3528	1487	43	i.	i.	PROPN
fnp-3528	1487	44	subcellular	subcellular	ADJ
fnp-3528	1487	45	localization	localization	NOUN
fnp-3528	1487	46	of	of	ADP
fnp-3528	1487	47	rat	rat	NOUN
fnp-3528	1487	48	abca5	abca5	PROPN
fnp-3528	1487	49	,	,	PUNCT
fnp-3528	1487	50	a	a	DET
fnp-3528	1487	51	rat	rat	NOUN
fnp-3528	1487	52	atp	atp	NOUN
fnp-3528	1487	53	-	-	PUNCT
fnp-3528	1487	54	binding	binding	ADJ
fnp-3528	1487	55	-	-	PUNCT
fnp-3528	1487	56	cassette	cassette	NOUN
fnp-3528	1487	57	transporter	transporter	NOUN
fnp-3528	1487	58	expressed	express	VERB
fnp-3528	1487	59	in	in	ADP
fnp-3528	1487	60	leydig	leydig	NOUN
fnp-3528	1487	61	cells	cell	NOUN
fnp-3528	1487	62	,	,	PUNCT
fnp-3528	1487	63	and	and	CCONJ
fnp-3528	1487	64	characterization	characterization	NOUN
fnp-3528	1487	65	of	of	ADP
fnp-3528	1487	66	its	its	PRON
fnp-3528	1487	67	splice	splice	NOUN
fnp-3528	1487	68	variant	variant	NOUN
fnp-3528	1487	69	apparently	apparently	ADV
fnp-3528	1487	70	encoding	encode	VERB
fnp-3528	1487	71	a	a	DET
fnp-3528	1487	72	half	half	ADJ
fnp-3528	1487	73	-	-	PUNCT
fnp-3528	1487	74	transporter	transporter	NOUN
fnp-3528	1487	75	.	.	PUNCT
fnp-3528	1488	1	biochem	biochem	PROPN
fnp-3528	1488	2	j	j	PROPN
fnp-3528	1488	3	2006	2006	NUM
fnp-3528	1488	4	,	,	PUNCT
fnp-3528	1488	5	393	393	NUM
fnp-3528	1488	6	,	,	PUNCT
fnp-3528	1488	7	79	79	NUM
fnp-3528	1488	8	-	-	SYM
fnp-3528	1488	9	87	87	NUM
fnp-3528	1488	10	.	.	PUNCT
fnp-3528	1489	1	hu	hu	PROPN
fnp-3528	1489	2	,	,	PUNCT
fnp-3528	1489	3	j.	j.	PROPN
fnp-3528	1489	4	y.	y.	PROPN
fnp-3528	1489	5	;	;	PUNCT
fnp-3528	1489	6	yang	yang	PROPN
fnp-3528	1489	7	,	,	PUNCT
fnp-3528	1489	8	p.	p.	PROPN
fnp-3528	1489	9	;	;	PUNCT
fnp-3528	1489	10	wegner	wegner	PROPN
fnp-3528	1489	11	,	,	PUNCT
fnp-3528	1489	12	d.	d.	PROPN
fnp-3528	1489	13	j.	j.	PROPN
fnp-3528	1489	14	;	;	PUNCT
fnp-3528	1489	15	heins	heins	PROPN
fnp-3528	1489	16	,	,	PUNCT
fnp-3528	1489	17	h.	h.	PROPN
fnp-3528	1489	18	b.	b.	PROPN
fnp-3528	1489	19	;	;	PUNCT
fnp-3528	1489	20	luke	luke	PROPN
fnp-3528	1489	21	,	,	PUNCT
fnp-3528	1489	22	c.	c.	PROPN
fnp-3528	1489	23	j.	j.	PROPN
fnp-3528	1489	24	;	;	PUNCT
fnp-3528	1489	25	li	li	PROPN
fnp-3528	1489	26	,	,	PUNCT
fnp-3528	1489	27	f.	f.	PROPN
fnp-3528	1489	28	;	;	PUNCT
fnp-3528	1489	29	white	white	PROPN
fnp-3528	1489	30	,	,	PUNCT
fnp-3528	1489	31	f.	f.	PROPN
fnp-3528	1489	32	v.	v.	PROPN
fnp-3528	1489	33	;	;	PUNCT
fnp-3528	1489	34	silverman	silverman	NOUN
fnp-3528	1489	35	,	,	PUNCT
fnp-3528	1489	36	g.	g.	PROPN
fnp-3528	1489	37	a.	a.	PROPN
fnp-3528	1489	38	;	;	PUNCT
fnp-3528	1489	39	sessions	session	NOUN
fnp-3528	1489	40	cole	cole	PROPN
fnp-3528	1489	41	,	,	PUNCT
fnp-3528	1489	42	f.	f.	PROPN
fnp-3528	1489	43	;	;	PUNCT
fnp-3528	1489	44	wambach	wambach	PROPN
fnp-3528	1489	45	,	,	PUNCT
fnp-3528	1489	46	j.	j.	PROPN
fnp-3528	1489	47	a.	a.	PROPN
fnp-3528	1489	48	functional	functional	ADJ
fnp-3528	1489	49	characterization	characterization	NOUN
fnp-3528	1489	50	of	of	ADP
fnp-3528	1489	51	four	four	NUM
fnp-3528	1489	52	atp	atp	NOUN
fnp-3528	1489	53	-	-	PUNCT
fnp-3528	1489	54	binding	bind	VERB
fnp-3528	1489	55	cassette	cassette	NOUN
fnp-3528	1489	56	transporter	transporter	NOUN
fnp-3528	1489	57	a3	a3	NOUN
fnp-3528	1489	58	gene	gene	NOUN
fnp-3528	1489	59	(	(	PUNCT
fnp-3528	1489	60	abca3	abca3	NOUN
fnp-3528	1489	61	)	)	PUNCT
fnp-3528	1489	62	variants	variant	NOUN
fnp-3528	1489	63	.	.	PUNCT
fnp-3528	1490	1	hum	hum	PROPN
fnp-3528	1490	2	mutat	mutat	PROPN
fnp-3528	1490	3	2020	2020	NUM
fnp-3528	1490	4	,	,	PUNCT
fnp-3528	1490	5	41	41	NUM
fnp-3528	1490	6	,	,	PUNCT
fnp-3528	1490	7	1298	1298	NUM
fnp-3528	1490	8	-	-	SYM
fnp-3528	1490	9	1307	1307	NUM
fnp-3528	1490	10	.	.	PUNCT
fnp-3528	1490	11	trompier	trompier	NOUN
fnp-3528	1490	12	,	,	PUNCT
fnp-3528	1490	13	d.	d.	PROPN
fnp-3528	1490	14	;	;	PUNCT
fnp-3528	1490	15	alibert	alibert	ADJ
fnp-3528	1490	16	,	,	PUNCT
fnp-3528	1490	17	m.	m.	NOUN
fnp-3528	1490	18	;	;	PUNCT
fnp-3528	1490	19	davanture	davanture	NOUN
fnp-3528	1490	20	,	,	PUNCT
fnp-3528	1490	21	s.	s.	PROPN
fnp-3528	1490	22	;	;	PUNCT
fnp-3528	1490	23	hamon	hamon	NOUN
fnp-3528	1490	24	,	,	PUNCT
fnp-3528	1490	25	y.	y.	PROPN
fnp-3528	1490	26	;	;	PUNCT
fnp-3528	1490	27	pierres	pierre	NOUN
fnp-3528	1490	28	,	,	PUNCT
fnp-3528	1490	29	m.	m.	NOUN
fnp-3528	1490	30	;	;	PUNCT
fnp-3528	1490	31	chimini	chimini	PROPN
fnp-3528	1490	32	,	,	PUNCT
fnp-3528	1490	33	g.	g.	PROPN
fnp-3528	1490	34	transition	transition	NOUN
fnp-3528	1490	35	from	from	ADP
fnp-3528	1490	36	dimers	dimer	NOUN
fnp-3528	1490	37	to	to	ADP
fnp-3528	1490	38	higher	high	ADJ
fnp-3528	1490	39	oligomeric	oligomeric	ADJ
fnp-3528	1490	40	forms	form	NOUN
fnp-3528	1490	41	occurs	occur	VERB
fnp-3528	1490	42	during	during	ADP
fnp-3528	1490	43	the	the	DET
fnp-3528	1490	44	atpase	atpase	PROPN
fnp-3528	1490	45	cycle	cycle	NOUN
fnp-3528	1490	46	of	of	ADP
fnp-3528	1490	47	the	the	DET
fnp-3528	1490	48	abca1	abca1	NOUN
fnp-3528	1490	49	transporter	transporter	NOUN
fnp-3528	1490	50	.	.	PUNCT
fnp-3528	1491	1	j	j	PROPN
fnp-3528	1491	2	biol	biol	PROPN
fnp-3528	1491	3	chem	chem	NOUN
fnp-3528	1491	4	2006	2006	NUM
fnp-3528	1491	5	,	,	PUNCT
fnp-3528	1491	6	281	281	NUM
fnp-3528	1491	7	,	,	PUNCT
fnp-3528	1491	8	20283	20283	NUM
fnp-3528	1491	9	-	-	SYM
fnp-3528	1491	10	90	90	NUM
fnp-3528	1491	11	.	.	PUNCT
fnp-3528	1492	1	takahashi	takahashi	PROPN
fnp-3528	1492	2	,	,	PUNCT
fnp-3528	1492	3	k.	k.	PROPN
fnp-3528	1492	4	;	;	PUNCT
fnp-3528	1492	5	kimura	kimura	NOUN
fnp-3528	1492	6	,	,	PUNCT
fnp-3528	1492	7	y.	y.	PROPN
fnp-3528	1492	8	;	;	PUNCT
fnp-3528	1492	9	kioka	kioka	NOUN
fnp-3528	1492	10	,	,	PUNCT
fnp-3528	1492	11	n.	n.	NOUN
fnp-3528	1492	12	;	;	PUNCT
fnp-3528	1492	13	matsuo	matsuo	PROPN
fnp-3528	1492	14	,	,	PUNCT
fnp-3528	1492	15	m.	m.	NOUN
fnp-3528	1492	16	;	;	PUNCT
fnp-3528	1492	17	ueda	ueda	PROPN
fnp-3528	1492	18	,	,	PUNCT
fnp-3528	1492	19	k.	k.	PROPN
fnp-3528	1492	20	purification	purification	PROPN
fnp-3528	1492	21	and	and	CCONJ
fnp-3528	1492	22	atpase	atpase	PROPN
fnp-3528	1492	23	activity	activity	NOUN
fnp-3528	1492	24	of	of	ADP
fnp-3528	1492	25	human	human	ADJ
fnp-3528	1492	26	abca1	abca1	NOUN
fnp-3528	1492	27	.	.	PUNCT
fnp-3528	1493	1	j	j	PROPN
fnp-3528	1493	2	biol	biol	PROPN
fnp-3528	1493	3	chem	chem	NOUN
fnp-3528	1493	4	2006	2006	NUM
fnp-3528	1493	5	,	,	PUNCT
fnp-3528	1493	6	281	281	NUM
fnp-3528	1493	7	,	,	PUNCT
fnp-3528	1493	8	10760	10760	NUM
fnp-3528	1493	9	-	-	SYM
fnp-3528	1493	10	8	8	NUM
fnp-3528	1493	11	.	.	PUNCT
fnp-3528	1494	1	gameiro	gameiro	NOUN
fnp-3528	1494	2	,	,	PUNCT
fnp-3528	1494	3	m.	m.	NOUN
fnp-3528	1494	4	;	;	PUNCT
fnp-3528	1494	5	silva	silva	PROPN
fnp-3528	1494	6	,	,	PUNCT
fnp-3528	1494	7	r.	r.	PROPN
fnp-3528	1494	8	;	;	PUNCT
fnp-3528	1494	9	rocha	rocha	PROPN
fnp-3528	1494	10	-	-	PUNCT
fnp-3528	1494	11	pereira	pereira	PROPN
fnp-3528	1494	12	,	,	PUNCT
fnp-3528	1494	13	c.	c.	PROPN
fnp-3528	1494	14	;	;	PUNCT
fnp-3528	1494	15	carmo	carmo	PROPN
fnp-3528	1494	16	,	,	PUNCT
fnp-3528	1494	17	h.	h.	PROPN
fnp-3528	1494	18	;	;	PUNCT
fnp-3528	1494	19	carvalho	carvalho	PROPN
fnp-3528	1494	20	,	,	PUNCT
fnp-3528	1494	21	f.	f.	PROPN
fnp-3528	1494	22	;	;	PUNCT
fnp-3528	1494	23	bastos	basto	NOUN
fnp-3528	1494	24	,	,	PUNCT
fnp-3528	1494	25	m.	m.	NOUN
fnp-3528	1494	26	l.	l.	PROPN
fnp-3528	1494	27	;	;	PUNCT
fnp-3528	1494	28	remiao	remiao	PROPN
fnp-3528	1494	29	,	,	PUNCT
fnp-3528	1494	30	f.	f.	PROPN
fnp-3528	1494	31	cellular	cellular	ADJ
fnp-3528	1494	32	models	model	NOUN
fnp-3528	1494	33	and	and	CCONJ
fnp-3528	1494	34	in	in	ADP
fnp-3528	1494	35	vitro	vitro	X
fnp-3528	1494	36	assays	assay	NOUN
fnp-3528	1494	37	for	for	ADP
fnp-3528	1494	38	the	the	DET
fnp-3528	1494	39	screening	screening	NOUN
fnp-3528	1494	40	of	of	ADP
fnp-3528	1494	41	modulators	modulator	NOUN
fnp-3528	1494	42	of	of	ADP
fnp-3528	1494	43	p	p	NOUN
fnp-3528	1494	44	-	-	PUNCT
fnp-3528	1494	45	gp	gp	NOUN
fnp-3528	1494	46	,	,	PUNCT
fnp-3528	1494	47	mrp	mrp	NOUN
fnp-3528	1494	48	and	and	CCONJ
fnp-3528	1494	49	bcrp	bcrp	ADV
fnp-3528	1494	50	.	.	PUNCT
fnp-3528	1495	1	molecules	molecule	NOUN
fnp-3528	1495	2	2017	2017	NUM
fnp-3528	1495	3	,	,	PUNCT
fnp-3528	1495	4	22	22	NUM
fnp-3528	1495	5	.	.	PUNCT
fnp-3528	1496	1	kraege	kraege	PROPN
fnp-3528	1496	2	,	,	PUNCT
fnp-3528	1496	3	s.	s.	PROPN
fnp-3528	1496	4	;	;	PUNCT
fnp-3528	1496	5	stefan	stefan	PROPN
fnp-3528	1496	6	,	,	PUNCT
fnp-3528	1496	7	k.	k.	PROPN
fnp-3528	1496	8	;	;	PUNCT
fnp-3528	1496	9	kohler	kohler	PROPN
fnp-3528	1496	10	,	,	PUNCT
fnp-3528	1496	11	s.	s.	PROPN
fnp-3528	1496	12	c.	c.	PROPN
fnp-3528	1496	13	;	;	PUNCT
fnp-3528	1496	14	wiese	wiese	PROPN
fnp-3528	1496	15	,	,	PUNCT
fnp-3528	1496	16	m.	m.	NOUN
fnp-3528	1496	17	optimization	optimization	NOUN
fnp-3528	1496	18	of	of	ADP
fnp-3528	1496	19	acryloylphenylcarboxamides	acryloylphenylcarboxamide	NOUN
fnp-3528	1496	20	as	as	ADP
fnp-3528	1496	21	inhibitors	inhibitor	NOUN
fnp-3528	1496	22	of	of	ADP
fnp-3528	1496	23	abcg2	abcg2	NOUN
fnp-3528	1496	24	and	and	CCONJ
fnp-3528	1496	25	comparison	comparison	NOUN
fnp-3528	1496	26	with	with	ADP
fnp-3528	1496	27	acryloylphenylcarboxylates	acryloylphenylcarboxylate	NOUN
fnp-3528	1496	28	.	.	PUNCT
fnp-3528	1497	1	chemmedchem	chemmedchem	PROPN
fnp-3528	1497	2	2016	2016	NUM
fnp-3528	1497	3	,	,	PUNCT
fnp-3528	1497	4	11	11	NUM
fnp-3528	1497	5	,	,	PUNCT
fnp-3528	1497	6	2547	2547	NUM
fnp-3528	1497	7	-	-	SYM
fnp-3528	1497	8	58	58	NUM
fnp-3528	1497	9	.	.	PUNCT
fnp-3528	1498	1	spindler	spindler	PROPN
fnp-3528	1498	2	,	,	PUNCT
fnp-3528	1498	3	a.	a.	PROPN
fnp-3528	1498	4	;	;	PUNCT
fnp-3528	1498	5	stefan	stefan	PROPN
fnp-3528	1498	6	,	,	PUNCT
fnp-3528	1498	7	k.	k.	PROPN
fnp-3528	1498	8	;	;	PUNCT
fnp-3528	1498	9	wiese	wiese	PROPN
fnp-3528	1498	10	,	,	PUNCT
fnp-3528	1498	11	m.	m.	NOUN
fnp-3528	1498	12	synthesis	synthesis	NOUN
fnp-3528	1498	13	and	and	CCONJ
fnp-3528	1498	14	investigation	investigation	NOUN
fnp-3528	1498	15	of	of	ADP
fnp-3528	1498	16	tetrahydro	tetrahydro	NOUN
fnp-3528	1498	17	-	-	PUNCT
fnp-3528	1498	18	beta	beta	NOUN
fnp-3528	1498	19	-	-	PUNCT
fnp-3528	1498	20	carboline	carboline	NOUN
fnp-3528	1498	21	derivatives	derivative	NOUN
fnp-3528	1498	22	as	as	ADP
fnp-3528	1498	23	inhibitors	inhibitor	NOUN
fnp-3528	1498	24	of	of	ADP
fnp-3528	1498	25	the	the	DET
fnp-3528	1498	26	breast	breast	NOUN
fnp-3528	1498	27	cancer	cancer	NOUN
fnp-3528	1498	28	resistance	resistance	NOUN
fnp-3528	1498	29	protein	protein	NOUN
fnp-3528	1498	30	(	(	PUNCT
fnp-3528	1498	31	abcg2	abcg2	NOUN
fnp-3528	1498	32	)	)	PUNCT
fnp-3528	1498	33	.	.	PUNCT
fnp-3528	1499	1	j	j	PROPN
fnp-3528	1499	2	med	med	PROPN
fnp-3528	1499	3	chem	chem	NOUN
fnp-3528	1499	4	2016	2016	NUM
fnp-3528	1499	5	,	,	PUNCT
fnp-3528	1499	6	59	59	NUM
fnp-3528	1499	7	,	,	PUNCT
fnp-3528	1499	8	6121	6121	NUM
fnp-3528	1499	9	-	-	SYM
fnp-3528	1499	10	35	35	NUM
fnp-3528	1499	11	.	.	PUNCT
fnp-3528	1500	1	kraege	kraege	PROPN
fnp-3528	1500	2	,	,	PUNCT
fnp-3528	1500	3	s.	s.	PROPN
fnp-3528	1500	4	;	;	PUNCT
fnp-3528	1500	5	stefan	stefan	PROPN
fnp-3528	1500	6	,	,	PUNCT
fnp-3528	1500	7	k.	k.	PROPN
fnp-3528	1500	8	;	;	PUNCT
fnp-3528	1500	9	juvale	juvale	PROPN
fnp-3528	1500	10	,	,	PUNCT
fnp-3528	1500	11	k.	k.	PROPN
fnp-3528	1500	12	;	;	PUNCT
fnp-3528	1500	13	ross	ross	PROPN
fnp-3528	1500	14	,	,	PUNCT
fnp-3528	1500	15	t.	t.	PROPN
fnp-3528	1500	16	;	;	PUNCT
fnp-3528	1500	17	willmes	willmes	ADV
fnp-3528	1500	18	,	,	PUNCT
fnp-3528	1500	19	t.	t.	PROPN
fnp-3528	1500	20	;	;	PUNCT
fnp-3528	1500	21	wiese	wiese	PROPN
fnp-3528	1500	22	,	,	PUNCT
fnp-3528	1500	23	m.	m.	NOUN
fnp-3528	1500	24	the	the	DET
fnp-3528	1500	25	combination	combination	NOUN
fnp-3528	1500	26	of	of	ADP
fnp-3528	1500	27	quinazoline	quinazoline	NOUN
fnp-3528	1500	28	and	and	CCONJ
fnp-3528	1500	29	chalcone	chalcone	NOUN
fnp-3528	1500	30	moieties	moiety	NOUN
fnp-3528	1500	31	leads	lead	VERB
fnp-3528	1500	32	to	to	ADP
fnp-3528	1500	33	novel	novel	NOUN
fnp-3528	1500	34	potent	potent	ADJ
fnp-3528	1500	35	heterodimeric	heterodimeric	ADJ
fnp-3528	1500	36	modulators	modulator	NOUN
fnp-3528	1500	37	of	of	ADP
fnp-3528	1500	38	breast	breast	NOUN
fnp-3528	1500	39	cancer	cancer	NOUN
fnp-3528	1500	40	resistance	resistance	NOUN
fnp-3528	1500	41	protein	protein	NOUN
fnp-3528	1500	42	(	(	PUNCT
fnp-3528	1500	43	bcrp	bcrp	ADV
fnp-3528	1500	44	/	/	SYM
fnp-3528	1500	45	abcg2	abcg2	NOUN
fnp-3528	1500	46	)	)	PUNCT
fnp-3528	1500	47	.	.	PUNCT
fnp-3528	1501	1	eur	eur	PROPN
fnp-3528	1501	2	j	j	PROPN
fnp-3528	1501	3	med	med	PROPN
fnp-3528	1501	4	chem	chem	NOUN
fnp-3528	1501	5	2016	2016	NUM
fnp-3528	1501	6	,	,	PUNCT
fnp-3528	1501	7	117	117	NUM
fnp-3528	1501	8	,	,	PUNCT
fnp-3528	1501	9	212	212	NUM
fnp-3528	1501	10	-	-	SYM
fnp-3528	1501	11	29	29	NUM
fnp-3528	1501	12	.	.	PUNCT
fnp-3528	1501	13	gelissen	gelissen	PROPN
fnp-3528	1501	14	,	,	PUNCT
fnp-3528	1501	15	i.	i.	PROPN
fnp-3528	1501	16	c.	c.	PROPN
fnp-3528	1501	17	;	;	PUNCT
fnp-3528	1501	18	brown	brown	PROPN
fnp-3528	1501	19	,	,	PUNCT
fnp-3528	1501	20	a.	a.	PROPN
fnp-3528	1501	21	j.	j.	PROPN
fnp-3528	1501	22	methods	methods	PROPN
fnp-3528	1501	23	mol	mol	ADP
fnp-3528	1501	24	biol	biol	PROPN
fnp-3528	1501	25	2017	2017	NUM
fnp-3528	1501	26	,	,	PUNCT
fnp-3528	1501	27	1583	1583	NUM
fnp-3528	1501	28	,	,	PUNCT
fnp-3528	1501	29	1–6	1–6	NUM
fnp-3528	1501	30	.	.	PUNCT
fnp-3528	1501	31	yang	yang	PROPN
fnp-3528	1501	32	,	,	PUNCT
fnp-3528	1501	33	a.	a.	NOUN
fnp-3528	1501	34	;	;	PUNCT
fnp-3528	1501	35	gelissen	gelissen	PROPN
fnp-3528	1501	36	,	,	PUNCT
fnp-3528	1501	37	i.	i.	PROPN
fnp-3528	1501	38	c.	c.	PROPN
fnp-3528	1501	39	abc	abc	PROPN
fnp-3528	1501	40	-	-	PUNCT
fnp-3528	1501	41	transporter	transporter	NOUN
fnp-3528	1501	42	mediated	mediate	VERB
fnp-3528	1501	43	sterol	sterol	NOUN
fnp-3528	1501	44	export	export	NOUN
fnp-3528	1501	45	from	from	ADP
fnp-3528	1501	46	cells	cell	NOUN
fnp-3528	1501	47	using	use	VERB
fnp-3528	1501	48	radiolabeled	radiolabele	VERB
fnp-3528	1501	49	sterols	sterol	NOUN
fnp-3528	1501	50	.	.	PUNCT
fnp-3528	1502	1	methods	method	NOUN
fnp-3528	1502	2	in	in	ADP
fnp-3528	1502	3	molecular	molecular	ADJ
fnp-3528	1502	4	biology	biology	NOUN
fnp-3528	1502	5	(	(	PUNCT
fnp-3528	1502	6	clifton	clifton	PROPN
fnp-3528	1502	7	,	,	PUNCT
fnp-3528	1502	8	n.j	n.j	PROPN
fnp-3528	1502	9	)	)	PUNCT
fnp-3528	1502	10	2017	2017	NUM
fnp-3528	1502	11	,	,	PUNCT
fnp-3528	1502	12	1583	1583	NUM
fnp-3528	1502	13	,	,	PUNCT
fnp-3528	1502	14	275	275	NUM
fnp-3528	1502	15	-	-	SYM
fnp-3528	1502	16	85	85	NUM
fnp-3528	1502	17	.	.	PUNCT
fnp-3528	1503	1	cattelotte	cattelotte	PROPN
fnp-3528	1503	2	,	,	PUNCT
fnp-3528	1503	3	j.	j.	PROPN
fnp-3528	1503	4	;	;	PUNCT
fnp-3528	1503	5	andre	andre	PROPN
fnp-3528	1503	6	,	,	PUNCT
fnp-3528	1503	7	p.	p.	PROPN
fnp-3528	1503	8	;	;	PUNCT
fnp-3528	1503	9	ouellet	ouellet	NOUN
fnp-3528	1503	10	,	,	PUNCT
fnp-3528	1503	11	m.	m.	NOUN
fnp-3528	1503	12	;	;	PUNCT
fnp-3528	1503	13	bourasset	bourasset	PROPN
fnp-3528	1503	14	,	,	PUNCT
fnp-3528	1503	15	f.	f.	PROPN
fnp-3528	1503	16	;	;	PUNCT
fnp-3528	1503	17	scherrmann	scherrmann	PROPN
fnp-3528	1503	18	,	,	PUNCT
fnp-3528	1503	19	j.	j.	PROPN
fnp-3528	1503	20	m.	m.	PROPN
fnp-3528	1503	21	;	;	PUNCT
fnp-3528	1503	22	cisternino	cisternino	PROPN
fnp-3528	1503	23	,	,	PUNCT
fnp-3528	1503	24	s.	s.	PROPN
fnp-3528	1503	25	in	in	ADP
fnp-3528	1503	26	situ	situ	NOUN
fnp-3528	1503	27	mouse	mouse	NOUN
fnp-3528	1503	28	carotid	carotid	NOUN
fnp-3528	1503	29	perfusion	perfusion	NOUN
fnp-3528	1503	30	model	model	NOUN
fnp-3528	1503	31	:	:	PUNCT
fnp-3528	1503	32	glucose	glucose	NOUN
fnp-3528	1503	33	and	and	CCONJ
fnp-3528	1503	34	cholesterol	cholesterol	NOUN
fnp-3528	1503	35	transport	transport	NOUN
fnp-3528	1503	36	in	in	ADP
fnp-3528	1503	37	the	the	DET
fnp-3528	1503	38	eye	eye	NOUN
fnp-3528	1503	39	and	and	CCONJ
fnp-3528	1503	40	brain	brain	NOUN
fnp-3528	1503	41	.	.	PUNCT
fnp-3528	1504	1	j	j	PROPN
fnp-3528	1504	2	cereb	cereb	PROPN
fnp-3528	1504	3	blood	blood	NOUN
fnp-3528	1504	4	flow	flow	NOUN
fnp-3528	1504	5	metab	metab	PROPN
fnp-3528	1504	6	2008	2008	NUM
fnp-3528	1504	7	,	,	PUNCT
fnp-3528	1504	8	28	28	NUM
fnp-3528	1504	9	,	,	PUNCT
fnp-3528	1504	10	1449	1449	NUM
fnp-3528	1504	11	-	-	SYM
fnp-3528	1504	12	59	59	NUM
fnp-3528	1504	13	.	.	PUNCT
fnp-3528	1505	1	li	li	PROPN
fnp-3528	1505	2	,	,	PUNCT
fnp-3528	1505	3	y.	y.	PROPN
fnp-3528	1505	4	;	;	PUNCT
fnp-3528	1505	5	kinting	kinting	NOUN
fnp-3528	1505	6	,	,	PUNCT
fnp-3528	1505	7	s.	s.	PROPN
fnp-3528	1505	8	;	;	PUNCT
fnp-3528	1505	9	hoppner	hoppner	X
fnp-3528	1505	10	,	,	PUNCT
fnp-3528	1505	11	s.	s.	PROPN
fnp-3528	1505	12	;	;	PUNCT
fnp-3528	1505	13	forstner	forstner	X
fnp-3528	1505	14	,	,	PUNCT
fnp-3528	1505	15	m.	m.	PROPN
fnp-3528	1505	16	e.	e.	PROPN
fnp-3528	1505	17	;	;	PUNCT
fnp-3528	1505	18	uhl	uhl	PROPN
fnp-3528	1505	19	,	,	PUNCT
fnp-3528	1505	20	o.	o.	PROPN
fnp-3528	1505	21	;	;	PUNCT
fnp-3528	1505	22	koletzko	koletzko	PROPN
fnp-3528	1505	23	,	,	PUNCT
fnp-3528	1505	24	b.	b.	PROPN
fnp-3528	1505	25	;	;	PUNCT
fnp-3528	1505	26	griese	griese	PROPN
fnp-3528	1505	27	,	,	PUNCT
fnp-3528	1505	28	m.	m.	NOUN
fnp-3528	1505	29	metabolic	metabolic	NOUN
fnp-3528	1505	30	labelling	labelling	NOUN
fnp-3528	1505	31	of	of	ADP
fnp-3528	1505	32	choline	choline	NOUN
fnp-3528	1505	33	phospholipids	phospholipid	NOUN
fnp-3528	1505	34	probes	probe	NOUN
fnp-3528	1505	35	abca3	abca3	VERB
fnp-3528	1505	36	transport	transport	NOUN
fnp-3528	1505	37	in	in	ADP
fnp-3528	1505	38	lamellar	lamellar	ADJ
fnp-3528	1505	39	bodies	body	NOUN
fnp-3528	1505	40	.	.	PUNCT
fnp-3528	1506	1	biochim	biochim	PROPN
fnp-3528	1506	2	biophys	biophy	NOUN
fnp-3528	1506	3	acta	acta	PROPN
fnp-3528	1506	4	mol	mol	ADP
fnp-3528	1506	5	cell	cell	NOUN
fnp-3528	1506	6	biol	biol	NOUN
fnp-3528	1506	7	lipids	lipid	VERB
fnp-3528	1506	8	2019	2019	NUM
fnp-3528	1506	9	,	,	PUNCT
fnp-3528	1506	10	1864	1864	NUM
fnp-3528	1506	11	,	,	PUNCT
fnp-3528	1506	12	158516	158516	NUM
fnp-3528	1506	13	.	.	PUNCT
fnp-3528	1507	1	hoppner	hoppner	NOUN
fnp-3528	1507	2	,	,	PUNCT
fnp-3528	1507	3	s.	s.	PROPN
fnp-3528	1507	4	;	;	PUNCT
fnp-3528	1507	5	kinting	kinting	NOUN
fnp-3528	1507	6	,	,	PUNCT
fnp-3528	1507	7	s.	s.	PROPN
fnp-3528	1507	8	;	;	PUNCT
fnp-3528	1507	9	torrano	torrano	PROPN
fnp-3528	1507	10	,	,	PUNCT
fnp-3528	1507	11	a.	a.	NOUN
fnp-3528	1507	12	a.	a.	PROPN
fnp-3528	1507	13	;	;	PUNCT
fnp-3528	1507	14	schindlbeck	schindlbeck	NOUN
fnp-3528	1507	15	,	,	PUNCT
fnp-3528	1507	16	u.	u.	PROPN
fnp-3528	1507	17	;	;	PUNCT
fnp-3528	1507	18	brauchle	brauchle	PROPN
fnp-3528	1507	19	,	,	PUNCT
fnp-3528	1507	20	c.	c.	PROPN
fnp-3528	1507	21	;	;	PUNCT
fnp-3528	1507	22	zarbock	zarbock	NOUN
fnp-3528	1507	23	,	,	PUNCT
fnp-3528	1507	24	r.	r.	PROPN
fnp-3528	1507	25	;	;	PUNCT
fnp-3528	1507	26	wittmann	wittmann	PROPN
fnp-3528	1507	27	,	,	PUNCT
fnp-3528	1507	28	t.	t.	PROPN
fnp-3528	1507	29	;	;	PUNCT
fnp-3528	1507	30	griese	griese	PROPN
fnp-3528	1507	31	,	,	PUNCT
fnp-3528	1507	32	m.	m.	NOUN
fnp-3528	1507	33	quantification	quantification	NOUN
fnp-3528	1507	34	of	of	ADP
fnp-3528	1507	35	volume	volume	NOUN
fnp-3528	1507	36	and	and	CCONJ
fnp-3528	1507	37	lipid	lipid	NOUN
fnp-3528	1507	38	filling	filling	NOUN
fnp-3528	1507	39	of	of	ADP
fnp-3528	1507	40	intracellular	intracellular	ADJ
fnp-3528	1507	41	vesicles	vesicle	NOUN
fnp-3528	1507	42	carrying	carry	VERB
fnp-3528	1507	43	the	the	DET
fnp-3528	1507	44	abca3	abca3	NOUN
fnp-3528	1507	45	transporter	transporter	NOUN
fnp-3528	1507	46	.	.	PUNCT
fnp-3528	1508	1	biochim	biochim	PROPN
fnp-3528	1508	2	biophys	biophy	NOUN
fnp-3528	1508	3	acta	acta	PROPN
fnp-3528	1508	4	mol	mol	ADP
fnp-3528	1508	5	cell	cell	NOUN
fnp-3528	1508	6	res	re	NOUN
fnp-3528	1508	7	2017	2017	NUM
fnp-3528	1508	8	,	,	PUNCT
fnp-3528	1508	9	1864	1864	NUM
fnp-3528	1508	10	,	,	PUNCT
fnp-3528	1508	11	2330	2330	NUM
fnp-3528	1508	12	-	-	SYM
fnp-3528	1508	13	5	5	NUM
fnp-3528	1508	14	.	.	PUNCT
fnp-3528	1509	1	cox	cox	PROPN
fnp-3528	1509	2	,	,	PUNCT
fnp-3528	1509	3	j.	j.	PROPN
fnp-3528	1509	4	v.	v.	PROPN
fnp-3528	1509	5	;	;	PUNCT
fnp-3528	1509	6	abdelrahman	abdelrahman	NOUN
fnp-3528	1509	7	,	,	PUNCT
fnp-3528	1509	8	y.	y.	PROPN
fnp-3528	1509	9	m.	m.	NOUN
fnp-3528	1509	10	;	;	PUNCT
fnp-3528	1509	11	peters	peters	PROPN
fnp-3528	1509	12	,	,	PUNCT
fnp-3528	1509	13	j.	j.	PROPN
fnp-3528	1509	14	;	;	PUNCT
fnp-3528	1509	15	naher	naher	ADV
fnp-3528	1509	16	,	,	PUNCT
fnp-3528	1509	17	n.	n.	PROPN
fnp-3528	1509	18	;	;	PUNCT
fnp-3528	1509	19	belland	belland	PROPN
fnp-3528	1509	20	,	,	PUNCT
fnp-3528	1509	21	r.	r.	PROPN
fnp-3528	1509	22	j.	j.	PROPN
fnp-3528	1509	23	chlamydia	chlamydia	PROPN
fnp-3528	1509	24	trachomatis	trachomatis	ADJ
fnp-3528	1509	25	utilizes	utilize	VERB
fnp-3528	1509	26	the	the	DET
fnp-3528	1509	27	mammalian	mammalian	ADJ
fnp-3528	1509	28	cla1	cla1	PROPN
fnp-3528	1509	29	lipid	lipid	NOUN
fnp-3528	1509	30	transporter	transporter	NOUN
fnp-3528	1509	31	to	to	PART
fnp-3528	1509	32	acquire	acquire	VERB
fnp-3528	1509	33	host	host	NOUN
fnp-3528	1509	34	phosphatidylcholine	phosphatidylcholine	NOUN
fnp-3528	1509	35	essential	essential	ADJ
fnp-3528	1509	36	for	for	ADP
fnp-3528	1509	37	growth	growth	NOUN
fnp-3528	1509	38	.	.	PUNCT
fnp-3528	1510	1	cell	cell	NOUN
fnp-3528	1510	2	microbiol	microbiol	PROPN
fnp-3528	1510	3	2016	2016	NUM
fnp-3528	1510	4	,	,	PUNCT
fnp-3528	1510	5	18	18	NUM
fnp-3528	1510	6	,	,	PUNCT
fnp-3528	1510	7	305	305	NUM
fnp-3528	1510	8	-	-	SYM
fnp-3528	1510	9	18	18	NUM
fnp-3528	1510	10	.	.	PUNCT
fnp-3528	1511	1	sankaranarayanan	sankaranarayanan	PROPN
fnp-3528	1511	2	,	,	PUNCT
fnp-3528	1511	3	s.	s.	PROPN
fnp-3528	1511	4	;	;	PUNCT
fnp-3528	1511	5	kellner	kellner	PROPN
fnp-3528	1511	6	-	-	PUNCT
fnp-3528	1511	7	weibel	weibel	PROPN
fnp-3528	1511	8	,	,	PUNCT
fnp-3528	1511	9	g.	g.	PROPN
fnp-3528	1511	10	;	;	PUNCT
fnp-3528	1511	11	de	de	X
fnp-3528	1511	12	la	la	PRON
fnp-3528	1511	13	llera	llera	PROPN
fnp-3528	1511	14	-	-	PUNCT
fnp-3528	1511	15	moya	moya	PROPN
fnp-3528	1511	16	,	,	PUNCT
fnp-3528	1511	17	m.	m.	NOUN
fnp-3528	1511	18	;	;	PUNCT
fnp-3528	1511	19	phillips	phillips	PROPN
fnp-3528	1511	20	,	,	PUNCT
fnp-3528	1511	21	m.	m.	PROPN
fnp-3528	1511	22	c.	c.	PROPN
fnp-3528	1511	23	;	;	PUNCT
fnp-3528	1511	24	asztalos	asztalos	PROPN
fnp-3528	1511	25	,	,	PUNCT
fnp-3528	1511	26	b.	b.	PROPN
fnp-3528	1511	27	f.	f.	PROPN
fnp-3528	1511	28	;	;	PUNCT
fnp-3528	1511	29	bittman	bittman	PROPN
fnp-3528	1511	30	,	,	PUNCT
fnp-3528	1511	31	r.	r.	PROPN
fnp-3528	1511	32	;	;	PUNCT
fnp-3528	1511	33	rothblat	rothblat	NOUN
fnp-3528	1511	34	,	,	PUNCT
fnp-3528	1511	35	g.	g.	PROPN
fnp-3528	1511	36	h.	h.	PROPN
fnp-3528	1512	1	a	a	DET
fnp-3528	1512	2	sensitive	sensitive	ADJ
fnp-3528	1512	3	assay	assay	NOUN
fnp-3528	1512	4	for	for	ADP
fnp-3528	1512	5	abca1	abca1	NOUN
fnp-3528	1512	6	-	-	PUNCT
fnp-3528	1512	7	mediated	mediate	VERB
fnp-3528	1512	8	cholesterol	cholesterol	NOUN
fnp-3528	1512	9	efflux	efflux	NOUN
fnp-3528	1512	10	using	use	VERB
fnp-3528	1512	11	bodipy	bodipy	NOUN
fnp-3528	1512	12	-	-	PUNCT
fnp-3528	1512	13	cholesterol	cholesterol	NOUN
fnp-3528	1512	14	.	.	PUNCT
fnp-3528	1513	1	j	j	PROPN
fnp-3528	1513	2	lipid	lipid	PROPN
fnp-3528	1513	3	res	re	NOUN
fnp-3528	1513	4	2011	2011	NUM
fnp-3528	1513	5	,	,	PUNCT
fnp-3528	1513	6	52	52	NUM
fnp-3528	1513	7	,	,	PUNCT
fnp-3528	1513	8	2332	2332	NUM
fnp-3528	1513	9	-	-	SYM
fnp-3528	1513	10	40	40	NUM
fnp-3528	1513	11	.	.	PUNCT
fnp-3528	1514	1	stearns	stearns	PROPN
fnp-3528	1514	2	,	,	PUNCT
fnp-3528	1514	3	m.	m.	PROPN
fnp-3528	1514	4	e.	e.	PROPN
fnp-3528	1514	5	;	;	PUNCT
fnp-3528	1514	6	jenkins	jenkins	PROPN
fnp-3528	1514	7	,	,	PUNCT
fnp-3528	1514	8	d.	d.	PROPN
fnp-3528	1514	9	p.	p.	PROPN
fnp-3528	1514	10	;	;	PUNCT
fnp-3528	1514	11	tew	tew	PROPN
fnp-3528	1514	12	,	,	PUNCT
fnp-3528	1514	13	k.	k.	PROPN
fnp-3528	1514	14	d.	d.	PROPN
fnp-3528	1514	15	dansylated	dansylated	PROPN
fnp-3528	1514	16	estramustine	estramustine	PROPN
fnp-3528	1514	17	,	,	PUNCT
fnp-3528	1514	18	a	a	DET
fnp-3528	1514	19	fluorescent	fluorescent	ADJ
fnp-3528	1514	20	probe	probe	NOUN
fnp-3528	1514	21	for	for	ADP
fnp-3528	1514	22	studies	study	NOUN
fnp-3528	1514	23	of	of	ADP
fnp-3528	1514	24	estramustine	estramustine	NOUN
fnp-3528	1514	25	uptake	uptake	NOUN
fnp-3528	1514	26	and	and	CCONJ
fnp-3528	1514	27	identification	identification	NOUN
fnp-3528	1514	28	of	of	ADP
fnp-3528	1514	29	intracellular	intracellular	ADJ
fnp-3528	1514	30	targets	target	NOUN
fnp-3528	1514	31	.	.	PUNCT
fnp-3528	1515	1	proc	proc	PROPN
fnp-3528	1515	2	natl	natl	PROPN
fnp-3528	1515	3	acad	acad	PROPN
fnp-3528	1515	4	sci	sci	PROPN
fnp-3528	1515	5	u	u	PROPN
fnp-3528	1515	6	s	s	PROPN
fnp-3528	1515	7	a	a	DET
fnp-3528	1515	8	1985	1985	NUM
fnp-3528	1515	9	,	,	PUNCT
fnp-3528	1515	10	82	82	NUM
fnp-3528	1515	11	,	,	PUNCT
fnp-3528	1515	12	8483	8483	NUM
fnp-3528	1515	13	-	-	SYM
fnp-3528	1515	14	7	7	NUM
fnp-3528	1515	15	.	.	PUNCT
fnp-3528	1516	1	bryan	bryan	PROPN
fnp-3528	1516	2	,	,	PUNCT
fnp-3528	1516	3	a.	a.	NOUN
fnp-3528	1516	4	;	;	PUNCT
fnp-3528	1516	5	watters	watter	NOUN
fnp-3528	1516	6	,	,	PUNCT
fnp-3528	1516	7	c.	c.	PROPN
fnp-3528	1516	8	;	;	PUNCT
fnp-3528	1516	9	koenig	koenig	PROPN
fnp-3528	1516	10	,	,	PUNCT
fnp-3528	1516	11	l.	l.	PROPN
fnp-3528	1516	12	;	;	PUNCT
fnp-3528	1516	13	youn	youn	PROPN
fnp-3528	1516	14	,	,	PUNCT
fnp-3528	1516	15	e.	e.	PROPN
fnp-3528	1516	16	;	;	PUNCT
fnp-3528	1516	17	olmos	olmos	PROPN
fnp-3528	1516	18	,	,	PUNCT
fnp-3528	1516	19	a.	a.	PROPN
fnp-3528	1516	20	;	;	PUNCT
fnp-3528	1516	21	li	li	PROPN
fnp-3528	1516	22	,	,	PUNCT
fnp-3528	1516	23	g.	g.	PROPN
fnp-3528	1516	24	;	;	PUNCT
fnp-3528	1516	25	williams	williams	PROPN
fnp-3528	1516	26	,	,	PUNCT
fnp-3528	1516	27	s.	s.	PROPN
fnp-3528	1516	28	c.	c.	PROPN
fnp-3528	1516	29	;	;	PUNCT
fnp-3528	1516	30	rumbaugh	rumbaugh	NOUN
fnp-3528	1516	31	,	,	PUNCT
fnp-3528	1516	32	k.	k.	PROPN
fnp-3528	1517	1	p.	p.	PROPN
fnp-3528	1517	2	human	human	ADJ
fnp-3528	1517	3	transcriptome	transcriptome	PROPN
fnp-3528	1517	4	analysis	analysis	NOUN
fnp-3528	1517	5	reveals	reveal	VERB
fnp-3528	1517	6	a	a	DET
fnp-3528	1517	7	potential	potential	ADJ
fnp-3528	1517	8	role	role	NOUN
fnp-3528	1517	9	for	for	ADP
fnp-3528	1517	10	active	active	ADJ
fnp-3528	1517	11	transport	transport	NOUN
fnp-3528	1517	12	in	in	ADP
fnp-3528	1517	13	the	the	DET
fnp-3528	1517	14	metabolism	metabolism	NOUN
fnp-3528	1517	15	of	of	ADP
fnp-3528	1517	16	pseudomonas	pseudomona	NOUN
fnp-3528	1517	17	aeruginosa	aeruginosa	NOUN
fnp-3528	1517	18	autoinducers	autoinducer	NOUN
fnp-3528	1517	19	.	.	PUNCT
fnp-3528	1518	1	microbes	microbe	NOUN
fnp-3528	1518	2	infect	infect	VERB
fnp-3528	1518	3	2010	2010	NUM
fnp-3528	1518	4	,	,	PUNCT
fnp-3528	1518	5	12	12	NUM
fnp-3528	1518	6	,	,	PUNCT
fnp-3528	1518	7	1042	1042	NUM
fnp-3528	1518	8	-	-	SYM
fnp-3528	1518	9	50	50	NUM
fnp-3528	1518	10	.	.	PUNCT
fnp-3528	1519	1	chaudhuri	chaudhuri	PROPN
fnp-3528	1519	2	,	,	PUNCT
fnp-3528	1519	3	a.	a.	PROPN
fnp-3528	1519	4	;	;	PUNCT
fnp-3528	1519	5	anand	anand	PROPN
fnp-3528	1519	6	,	,	PUNCT
fnp-3528	1519	7	d.	d.	PROPN
fnp-3528	1519	8	cholesterol	cholesterol	PROPN
fnp-3528	1519	9	:	:	PUNCT
fnp-3528	1519	10	revisiting	revisit	VERB
fnp-3528	1519	11	its	its	PRON
fnp-3528	1519	12	fluorescent	fluorescent	ADJ
fnp-3528	1519	13	journey	journey	NOUN
fnp-3528	1519	14	on	on	ADP
fnp-3528	1519	15	200th	200th	ADJ
fnp-3528	1519	16	anniversary	anniversary	NOUN
fnp-3528	1519	17	of	of	ADP
fnp-3528	1519	18	chevruel	chevruel	PROPN
fnp-3528	1519	19	’s	’s	PART
fnp-3528	1519	20	“	"	PUNCT
fnp-3528	1519	21	cholesterine	cholesterine	PROPN
fnp-3528	1519	22	”	"	PUNCT
fnp-3528	1519	23	.	.	PUNCT
fnp-3528	1519	24	biomed	biome	VERB
fnp-3528	1519	25	spectrosc	spectrosc	PROPN
fnp-3528	1519	26	imaging	image	VERB
fnp-3528	1519	27	2017	2017	NUM
fnp-3528	1519	28	,	,	PUNCT
fnp-3528	1519	29	6	6	NUM
fnp-3528	1519	30	,	,	PUNCT
fnp-3528	1519	31	1	1	NUM
fnp-3528	1519	32	-	-	SYM
fnp-3528	1519	33	24	24	NUM
fnp-3528	1519	34	.	.	PUNCT
fnp-3528	1520	1	solanko	solanko	PROPN
fnp-3528	1520	2	,	,	PUNCT
fnp-3528	1520	3	k.	k.	PROPN
fnp-3528	1520	4	a.	a.	PROPN
fnp-3528	1520	5	;	;	PUNCT
fnp-3528	1520	6	modzel	modzel	ADJ
fnp-3528	1520	7	,	,	PUNCT
fnp-3528	1520	8	m.	m.	NOUN
fnp-3528	1520	9	;	;	PUNCT
fnp-3528	1520	10	solanko	solanko	PROPN
fnp-3528	1520	11	,	,	PUNCT
fnp-3528	1520	12	l.	l.	PROPN
fnp-3528	1520	13	m.	m.	PROPN
fnp-3528	1520	14	;	;	PUNCT
fnp-3528	1520	15	wustner	wustner	PROPN
fnp-3528	1520	16	,	,	PUNCT
fnp-3528	1520	17	d.	d.	PROPN
fnp-3528	1520	18	fluorescent	fluorescent	PROPN
fnp-3528	1520	19	sterols	sterol	NOUN
fnp-3528	1520	20	and	and	CCONJ
fnp-3528	1520	21	cholesteryl	cholesteryl	NOUN
fnp-3528	1520	22	esters	ester	NOUN
fnp-3528	1520	23	as	as	ADP
fnp-3528	1520	24	probes	probe	NOUN
fnp-3528	1520	25	for	for	ADP
fnp-3528	1520	26	intracellular	intracellular	ADJ
fnp-3528	1520	27	cholesterol	cholesterol	NOUN
fnp-3528	1520	28	transport	transport	NOUN
fnp-3528	1520	29	.	.	PUNCT
fnp-3528	1521	1	lipid	lipid	ADJ
fnp-3528	1521	2	insights	insight	NOUN
fnp-3528	1521	3	2015	2015	NUM
fnp-3528	1521	4	,	,	PUNCT
fnp-3528	1521	5	8	8	NUM
fnp-3528	1521	6	,	,	PUNCT
fnp-3528	1521	7	95	95	NUM
fnp-3528	1521	8	-	-	SYM
fnp-3528	1521	9	114	114	NUM
fnp-3528	1521	10	.	.	PUNCT
fnp-3528	1522	1	invitrogen	invitrogen	PROPN
fnp-3528	1522	2	.	.	PUNCT
fnp-3528	1523	1	chapter	chapter	NOUN
fnp-3528	1523	2	13	13	NUM
fnp-3528	1523	3	probes	probe	NOUN
fnp-3528	1523	4	for	for	ADP
fnp-3528	1523	5	lipids	lipid	NOUN
fnp-3528	1523	6	and	and	CCONJ
fnp-3528	1523	7	membranes	membrane	NOUN
fnp-3528	1523	8	.	.	PUNCT
fnp-3528	1524	1	in	in	ADP
fnp-3528	1524	2	molecular	molecular	ADJ
fnp-3528	1524	3	probes	probe	NOUN
fnp-3528	1524	4	handbook	handbook	VERB
fnp-3528	1524	5	:	:	PUNCT
fnp-3528	1524	6	a	a	DET
fnp-3528	1524	7	guide	guide	NOUN
fnp-3528	1524	8	to	to	ADP
fnp-3528	1524	9	fluorescent	fluorescent	ADJ
fnp-3528	1524	10	probes	probe	NOUN
fnp-3528	1524	11	and	and	CCONJ
fnp-3528	1524	12	labeling	labeling	NOUN
fnp-3528	1524	13	technologies	technology	NOUN
fnp-3528	1524	14	,	,	PUNCT
fnp-3528	1524	15	thermofischer	thermofischer	NOUN
fnp-3528	1524	16	,	,	PUNCT
fnp-3528	1524	17	ed	ed	NOUN
fnp-3528	1524	18	.	.	PROPN
fnp-3528	1524	19	2010	2010	NUM
fnp-3528	1524	20	.	.	PUNCT
fnp-3528	1525	1	silbermann	silbermann	PROPN
fnp-3528	1525	2	,	,	PUNCT
fnp-3528	1525	3	k.	k.	PROPN
fnp-3528	1525	4	;	;	PUNCT
fnp-3528	1525	5	shah	shah	PROPN
fnp-3528	1525	6	,	,	PUNCT
fnp-3528	1525	7	c.	c.	PROPN
fnp-3528	1525	8	p.	p.	PROPN
fnp-3528	1525	9	;	;	PUNCT
fnp-3528	1525	10	sahu	sahu	PROPN
fnp-3528	1525	11	,	,	PUNCT
fnp-3528	1525	12	n.	n.	PROPN
fnp-3528	1525	13	u.	u.	PROPN
fnp-3528	1525	14	;	;	PUNCT
fnp-3528	1525	15	juvale	juvale	PROPN
fnp-3528	1525	16	,	,	PUNCT
fnp-3528	1525	17	k.	k.	PROPN
fnp-3528	1525	18	;	;	PUNCT
fnp-3528	1525	19	stefan	stefan	PROPN
fnp-3528	1525	20	,	,	PUNCT
fnp-3528	1525	21	s.	s.	PROPN
fnp-3528	1525	22	m.	m.	PROPN
fnp-3528	1525	23	;	;	PUNCT
fnp-3528	1525	24	kharkar	kharkar	PROPN
fnp-3528	1525	25	,	,	PUNCT
fnp-3528	1525	26	p.	p.	PROPN
fnp-3528	1525	27	s.	s.	PROPN
fnp-3528	1525	28	;	;	PUNCT
fnp-3528	1525	29	wiese	wiese	PROPN
fnp-3528	1525	30	,	,	PUNCT
fnp-3528	1525	31	m.	m.	NOUN
fnp-3528	1525	32	novel	novel	NOUN
fnp-3528	1525	33	chalcone	chalcone	NOUN
fnp-3528	1525	34	and	and	CCONJ
fnp-3528	1525	35	flavone	flavone	NOUN
fnp-3528	1525	36	derivatives	derivative	NOUN
fnp-3528	1525	37	as	as	ADP
fnp-3528	1525	38	selective	selective	ADJ
fnp-3528	1525	39	and	and	CCONJ
fnp-3528	1525	40	dual	dual	ADJ
fnp-3528	1525	41	inhibitors	inhibitor	NOUN
fnp-3528	1525	42	of	of	ADP
fnp-3528	1525	43	the	the	DET
fnp-3528	1525	44	transport	transport	NOUN
fnp-3528	1525	45	proteins	protein	NOUN
fnp-3528	1525	46	abcb1	abcb1	NOUN
fnp-3528	1525	47	and	and	CCONJ
fnp-3528	1525	48	abcg2	abcg2	NOUN
fnp-3528	1525	49	.	.	PUNCT
fnp-3528	1526	1	eur	eur	PROPN
fnp-3528	1526	2	j	j	PROPN
fnp-3528	1526	3	med	med	PROPN
fnp-3528	1526	4	chem	chem	NOUN
fnp-3528	1526	5	2019	2019	NUM
fnp-3528	1526	6	,	,	PUNCT
fnp-3528	1526	7	164	164	NUM
fnp-3528	1526	8	,	,	PUNCT
fnp-3528	1526	9	193	193	NUM
fnp-3528	1526	10	-	-	SYM
fnp-3528	1526	11	213	213	NUM
fnp-3528	1526	12	.	.	PUNCT
fnp-3528	1527	1	stefan	stefan	PROPN
fnp-3528	1527	2	,	,	PUNCT
fnp-3528	1527	3	k.	k.	PROPN
fnp-3528	1527	4	;	;	PUNCT
fnp-3528	1527	5	schmitt	schmitt	PROPN
fnp-3528	1527	6	,	,	PUNCT
fnp-3528	1527	7	s.	s.	PROPN
fnp-3528	1527	8	m.	m.	PROPN
fnp-3528	1527	9	;	;	PUNCT
fnp-3528	1527	10	wiese	wiese	PROPN
fnp-3528	1527	11	,	,	PUNCT
fnp-3528	1527	12	m.	m.	NOUN
fnp-3528	1527	13	9	9	NUM
fnp-3528	1527	14	-	-	PUNCT
fnp-3528	1527	15	deazapurines	deazapurine	NOUN
fnp-3528	1527	16	as	as	ADP
fnp-3528	1527	17	broad	broad	ADJ
fnp-3528	1527	18	-	-	PUNCT
fnp-3528	1527	19	spectrum	spectrum	NOUN
fnp-3528	1527	20	inhibitors	inhibitor	NOUN
fnp-3528	1527	21	of	of	ADP
fnp-3528	1527	22	the	the	DET
fnp-3528	1527	23	abc	abc	PROPN
fnp-3528	1527	24	transport	transport	NOUN
fnp-3528	1527	25	proteins	protein	NOUN
fnp-3528	1527	26	p	p	NOUN
fnp-3528	1527	27	-	-	PUNCT
fnp-3528	1527	28	glycoprotein	glycoprotein	NOUN
fnp-3528	1527	29	,	,	PUNCT
fnp-3528	1527	30	multidrug	multidrug	VERB
fnp-3528	1527	31	resistance	resistance	NOUN
fnp-3528	1527	32	-	-	PUNCT
fnp-3528	1527	33	associated	associate	VERB
fnp-3528	1527	34	protein	protein	NOUN
fnp-3528	1527	35	1	1	NUM
fnp-3528	1527	36	,	,	PUNCT
fnp-3528	1527	37	and	and	CCONJ
fnp-3528	1527	38	breast	breast	NOUN
fnp-3528	1527	39	cancer	cancer	NOUN
fnp-3528	1527	40	resistance	resistance	NOUN
fnp-3528	1527	41	protein	protein	NOUN
fnp-3528	1527	42	.	.	PUNCT
fnp-3528	1528	1	j	j	PROPN
fnp-3528	1528	2	med	med	PROPN
fnp-3528	1528	3	chem	chem	NOUN
fnp-3528	1528	4	2017	2017	NUM
fnp-3528	1528	5	,	,	PUNCT
fnp-3528	1528	6	60	60	NUM
fnp-3528	1528	7	,	,	PUNCT
fnp-3528	1528	8	8758	8758	NUM
fnp-3528	1528	9	-	-	SYM
fnp-3528	1528	10	80	80	NUM
fnp-3528	1528	11	.	.	PUNCT
fnp-3528	1528	12	schmitt	schmitt	PROPN
fnp-3528	1528	13	,	,	PUNCT
fnp-3528	1528	14	s.	s.	PROPN
fnp-3528	1528	15	m.	m.	PROPN
fnp-3528	1528	16	;	;	PUNCT
fnp-3528	1528	17	stefan	stefan	PROPN
fnp-3528	1528	18	,	,	PUNCT
fnp-3528	1528	19	k.	k.	PROPN
fnp-3528	1528	20	;	;	PUNCT
fnp-3528	1528	21	wiese	wiese	PROPN
fnp-3528	1528	22	,	,	PUNCT
fnp-3528	1528	23	m.	m.	NOUN
fnp-3528	1528	24	pyrrolopyrimidine	pyrrolopyrimidine	NOUN
fnp-3528	1528	25	derivatives	derivative	NOUN
fnp-3528	1528	26	as	as	ADP
fnp-3528	1528	27	novel	novel	ADJ
fnp-3528	1528	28	inhibitors	inhibitor	NOUN
fnp-3528	1528	29	of	of	ADP
fnp-3528	1528	30	multidrug	multidrug	NOUN
fnp-3528	1528	31	resistance	resistance	NOUN
fnp-3528	1528	32	-	-	PUNCT
fnp-3528	1528	33	associated	associate	VERB
fnp-3528	1528	34	protein	protein	NOUN
fnp-3528	1528	35	1	1	NUM
fnp-3528	1528	36	(	(	PUNCT
fnp-3528	1528	37	mrp1	mrp1	NOUN
fnp-3528	1528	38	,	,	PUNCT
fnp-3528	1528	39	abcc1	abcc1	PROPN
fnp-3528	1528	40	)	)	PUNCT
fnp-3528	1528	41	.	.	PUNCT
fnp-3528	1529	1	j	j	PROPN
fnp-3528	1529	2	med	med	PROPN
fnp-3528	1529	3	chem	chem	NOUN
fnp-3528	1529	4	2016	2016	NUM
fnp-3528	1529	5	,	,	PUNCT
fnp-3528	1529	6	59	59	NUM
fnp-3528	1529	7	,	,	PUNCT
fnp-3528	1529	8	3018	3018	NUM
fnp-3528	1529	9	-	-	SYM
fnp-3528	1529	10	33	33	NUM
fnp-3528	1529	11	.	.	PUNCT
fnp-3528	1530	1	stefan	stefan	PROPN
fnp-3528	1530	2	,	,	PUNCT
fnp-3528	1530	3	k.	k.	PROPN
fnp-3528	1530	4	etablierung	etablierung	PROPN
fnp-3528	1530	5	und	und	PROPN
fnp-3528	1530	6	anwendung	anwendung	PROPN
fnp-3528	1530	7	unterschiedlicher	unterschiedlicher	PROPN
fnp-3528	1530	8	kolorimetrischer	kolorimetrischer	PROPN
fnp-3528	1530	9	detektionsmethoden	detektionsmethoden	PROPN
fnp-3528	1530	10	zur	zur	PROPN
fnp-3528	1530	11	aktivitätsbestimmung	aktivitätsbestimmung	PROPN
fnp-3528	1530	12	von	von	PROPN
fnp-3528	1530	13	modulatoren	modulatoren	PROPN
fnp-3528	1530	14	der	der	PROPN
fnp-3528	1530	15	abc	abc	PROPN
fnp-3528	1530	16	-	-	PUNCT
fnp-3528	1530	17	transporter	transporter	NOUN
fnp-3528	1530	18	abcb1	abcb1	NOUN
fnp-3528	1530	19	,	,	PUNCT
fnp-3528	1530	20	abcc1	abcc1	PROPN
fnp-3528	1530	21	und	und	VERB
fnp-3528	1530	22	abcg2	abcg2	PROPN
fnp-3528	1530	23	.	.	PUNCT
fnp-3528	1531	1	rheinische	rheinische	PROPN
fnp-3528	1531	2	friedrich	friedrich	PROPN
fnp-3528	1531	3	-	-	PUNCT
fnp-3528	1531	4	wilhelms	wilhelm	NOUN
fnp-3528	1531	5	-	-	PUNCT
fnp-3528	1531	6	universität	universität	NOUN
fnp-3528	1531	7	bonn	bonn	NOUN
fnp-3528	1531	8	,	,	PUNCT
fnp-3528	1531	9	2020	2020	NUM
fnp-3528	1531	10	.	.	PUNCT
fnp-3528	1532	1	mack	mack	PROPN
fnp-3528	1532	2	,	,	PUNCT
fnp-3528	1532	3	j.	j.	PROPN
fnp-3528	1532	4	t.	t.	PROPN
fnp-3528	1532	5	;	;	PUNCT
fnp-3528	1532	6	beljanski	beljanski	PROPN
fnp-3528	1532	7	,	,	PUNCT
fnp-3528	1532	8	v.	v.	PROPN
fnp-3528	1532	9	;	;	PUNCT
fnp-3528	1532	10	soulika	soulika	PROPN
fnp-3528	1532	11	,	,	PUNCT
fnp-3528	1532	12	a.	a.	NOUN
fnp-3528	1532	13	m.	m.	NOUN
fnp-3528	1532	14	;	;	PUNCT
fnp-3528	1532	15	townsend	townsend	PROPN
fnp-3528	1532	16	,	,	PUNCT
fnp-3528	1532	17	d.	d.	PROPN
fnp-3528	1532	18	m.	m.	PROPN
fnp-3528	1532	19	;	;	PUNCT
fnp-3528	1532	20	brown	brown	PROPN
fnp-3528	1532	21	,	,	PUNCT
fnp-3528	1532	22	c.	c.	PROPN
fnp-3528	1532	23	b.	b.	PROPN
fnp-3528	1532	24	;	;	PUNCT
fnp-3528	1532	25	davis	davis	PROPN
fnp-3528	1532	26	,	,	PUNCT
fnp-3528	1532	27	w.	w.	PROPN
fnp-3528	1532	28	;	;	PUNCT
fnp-3528	1532	29	tew	tew	PROPN
fnp-3528	1532	30	,	,	PUNCT
fnp-3528	1532	31	k.	k.	PROPN
fnp-3528	1532	32	d.	d.	PROPN
fnp-3528	1532	33	"	"	PUNCT
fnp-3528	1532	34	skittish	skittish	ADJ
fnp-3528	1532	35	"	"	PUNCT
fnp-3528	1532	36	abca2	abca2	NOUN
fnp-3528	1532	37	knockout	knockout	NOUN
fnp-3528	1532	38	mice	mice	NOUN
fnp-3528	1532	39	display	display	NOUN
fnp-3528	1532	40	tremor	tremor	NOUN
fnp-3528	1532	41	,	,	PUNCT
fnp-3528	1532	42	hyperactivity	hyperactivity	NOUN
fnp-3528	1532	43	,	,	PUNCT
fnp-3528	1532	44	and	and	CCONJ
fnp-3528	1532	45	abnormal	abnormal	ADJ
fnp-3528	1532	46	myelin	myelin	NOUN
fnp-3528	1532	47	ultrastructure	ultrastructure	NOUN
fnp-3528	1532	48	in	in	ADP
fnp-3528	1532	49	the	the	DET
fnp-3528	1532	50	central	central	ADJ
fnp-3528	1532	51	nervous	nervous	ADJ
fnp-3528	1532	52	system	system	NOUN
fnp-3528	1532	53	.	.	PUNCT
fnp-3528	1533	1	mol	mol	ADP
fnp-3528	1533	2	cell	cell	NOUN
fnp-3528	1533	3	biol	biol	NOUN
fnp-3528	1533	4	2007	2007	NUM
fnp-3528	1533	5	,	,	PUNCT
fnp-3528	1533	6	27	27	NUM
fnp-3528	1533	7	,	,	PUNCT
fnp-3528	1533	8	44	44	NUM
fnp-3528	1533	9	-	-	SYM
fnp-3528	1533	10	53	53	NUM
fnp-3528	1533	11	.	.	PUNCT
fnp-3528	1534	1	ban	ban	NOUN
fnp-3528	1534	2	,	,	PUNCT
fnp-3528	1534	3	n.	n.	NOUN
fnp-3528	1534	4	;	;	PUNCT
fnp-3528	1534	5	matsumura	matsumura	ADV
fnp-3528	1534	6	,	,	PUNCT
fnp-3528	1534	7	y.	y.	PROPN
fnp-3528	1534	8	;	;	PUNCT
fnp-3528	1534	9	sakai	sakai	PROPN
fnp-3528	1534	10	,	,	PUNCT
fnp-3528	1534	11	h.	h.	PROPN
fnp-3528	1534	12	;	;	PUNCT
fnp-3528	1534	13	takanezawa	takanezawa	NOUN
fnp-3528	1534	14	,	,	PUNCT
fnp-3528	1534	15	y.	y.	PROPN
fnp-3528	1534	16	;	;	PUNCT
fnp-3528	1534	17	sasaki	sasaki	PROPN
fnp-3528	1534	18	,	,	PUNCT
fnp-3528	1534	19	m.	m.	NOUN
fnp-3528	1534	20	;	;	PUNCT
fnp-3528	1534	21	arai	arai	PROPN
fnp-3528	1534	22	,	,	PUNCT
fnp-3528	1534	23	h.	h.	PROPN
fnp-3528	1534	24	;	;	PUNCT
fnp-3528	1534	25	inagaki	inagaki	PROPN
fnp-3528	1534	26	,	,	PUNCT
fnp-3528	1534	27	n.	n.	PROPN
fnp-3528	1534	28	abca3	abca3	PROPN
fnp-3528	1534	29	as	as	ADP
fnp-3528	1534	30	a	a	DET
fnp-3528	1534	31	lipid	lipid	NOUN
fnp-3528	1534	32	transporter	transporter	NOUN
fnp-3528	1534	33	in	in	ADP
fnp-3528	1534	34	pulmonary	pulmonary	ADJ
fnp-3528	1534	35	surfactant	surfactant	ADJ
fnp-3528	1534	36	biogenesis	biogenesis	NOUN
fnp-3528	1534	37	.	.	PUNCT
fnp-3528	1535	1	j	j	PROPN
fnp-3528	1535	2	biol	biol	PROPN
fnp-3528	1535	3	chem	chem	NOUN
fnp-3528	1535	4	2007	2007	NUM
fnp-3528	1535	5	,	,	PUNCT
fnp-3528	1535	6	282	282	NUM
fnp-3528	1535	7	,	,	PUNCT
fnp-3528	1535	8	9628	9628	NUM
fnp-3528	1535	9	-	-	SYM
fnp-3528	1535	10	34	34	NUM
fnp-3528	1535	11	.	.	PUNCT
fnp-3528	1536	1	hammel	hammel	PROPN
fnp-3528	1536	2	,	,	PUNCT
fnp-3528	1536	3	m.	m.	NOUN
fnp-3528	1536	4	;	;	PUNCT
fnp-3528	1536	5	michel	michel	PROPN
fnp-3528	1536	6	,	,	PUNCT
fnp-3528	1536	7	g.	g.	PROPN
fnp-3528	1536	8	;	;	PUNCT
fnp-3528	1536	9	hoefer	hoefer	X
fnp-3528	1536	10	,	,	PUNCT
fnp-3528	1536	11	c.	c.	NOUN
fnp-3528	1536	12	;	;	PUNCT
fnp-3528	1536	13	klaften	klaften	ADJ
fnp-3528	1536	14	,	,	PUNCT
fnp-3528	1536	15	m.	m.	NOUN
fnp-3528	1536	16	;	;	PUNCT
fnp-3528	1536	17	müller	müller	NOUN
fnp-3528	1536	18	-	-	PUNCT
fnp-3528	1536	19	höcker	höcker	PROPN
fnp-3528	1536	20	,	,	PUNCT
fnp-3528	1536	21	j.	j.	PROPN
fnp-3528	1536	22	;	;	PUNCT
fnp-3528	1536	23	de	de	X
fnp-3528	1536	24	angelis	angelis	PROPN
fnp-3528	1536	25	,	,	PUNCT
fnp-3528	1536	26	m.	m.	PROPN
fnp-3528	1536	27	h.	h.	PROPN
fnp-3528	1536	28	;	;	PUNCT
fnp-3528	1536	29	holzinger	holzinger	ADV
fnp-3528	1536	30	,	,	PUNCT
fnp-3528	1536	31	a.	a.	NOUN
fnp-3528	1536	32	targeted	target	VERB
fnp-3528	1536	33	inactivation	inactivation	NOUN
fnp-3528	1536	34	of	of	ADP
fnp-3528	1536	35	the	the	DET
fnp-3528	1536	36	murine	murine	ADJ
fnp-3528	1536	37	abca3	abca3	PROPN
fnp-3528	1537	1	gene	gene	NOUN
fnp-3528	1537	2	leads	lead	VERB
fnp-3528	1537	3	to	to	ADP
fnp-3528	1537	4	respiratory	respiratory	ADJ
fnp-3528	1537	5	failure	failure	NOUN
fnp-3528	1537	6	in	in	ADP
fnp-3528	1537	7	newborns	newborn	NOUN
fnp-3528	1537	8	with	with	ADP
fnp-3528	1537	9	defective	defective	ADJ
fnp-3528	1537	10	lamellar	lamellar	ADJ
fnp-3528	1537	11	bodies	body	NOUN
fnp-3528	1537	12	.	.	PUNCT
fnp-3528	1538	1	biochem	biochem	PROPN
fnp-3528	1538	2	biophys	biophys	PROPN
fnp-3528	1538	3	res	re	NOUN
fnp-3528	1538	4	commun	commun	PROPN
fnp-3528	1538	5	2007	2007	NUM
fnp-3528	1538	6	,	,	PUNCT
fnp-3528	1538	7	359	359	NUM
fnp-3528	1538	8	,	,	PUNCT
fnp-3528	1538	9	947	947	NUM
fnp-3528	1538	10	-	-	SYM
fnp-3528	1538	11	51	51	NUM
fnp-3528	1538	12	.	.	PUNCT
fnp-3528	1539	1	beers	beer	NOUN
fnp-3528	1539	2	,	,	PUNCT
fnp-3528	1539	3	m.	m.	PROPN
fnp-3528	1539	4	f.	f.	PROPN
fnp-3528	1539	5	;	;	PUNCT
fnp-3528	1539	6	knudsen	knudsen	PROPN
fnp-3528	1539	7	,	,	PUNCT
fnp-3528	1539	8	l.	l.	PROPN
fnp-3528	1539	9	;	;	PUNCT
fnp-3528	1539	10	tomer	tomer	PROPN
fnp-3528	1539	11	,	,	PUNCT
fnp-3528	1539	12	y.	y.	PROPN
fnp-3528	1539	13	;	;	PUNCT
fnp-3528	1539	14	maronn	maronn	PROPN
fnp-3528	1539	15	,	,	PUNCT
fnp-3528	1539	16	j.	j.	PROPN
fnp-3528	1539	17	;	;	PUNCT
fnp-3528	1539	18	zhao	zhao	X
fnp-3528	1539	19	,	,	PUNCT
fnp-3528	1539	20	m.	m.	NOUN
fnp-3528	1539	21	;	;	PUNCT
fnp-3528	1539	22	ochs	och	NOUN
fnp-3528	1539	23	,	,	PUNCT
fnp-3528	1539	24	m.	m.	NOUN
fnp-3528	1539	25	;	;	PUNCT
fnp-3528	1539	26	mulugeta	mulugeta	PROPN
fnp-3528	1539	27	,	,	PUNCT
fnp-3528	1539	28	s.	s.	PROPN
fnp-3528	1539	29	aberrant	aberrant	PROPN
fnp-3528	1539	30	lung	lung	NOUN
fnp-3528	1539	31	remodeling	remodeling	NOUN
fnp-3528	1539	32	in	in	ADP
fnp-3528	1539	33	a	a	DET
fnp-3528	1539	34	mouse	mouse	NOUN
fnp-3528	1539	35	model	model	NOUN
fnp-3528	1539	36	of	of	ADP
fnp-3528	1539	37	surfactant	surfactant	ADJ
fnp-3528	1539	38	dysregulation	dysregulation	NOUN
fnp-3528	1539	39	induced	induce	VERB
fnp-3528	1539	40	by	by	ADP
fnp-3528	1539	41	modulation	modulation	NOUN
fnp-3528	1539	42	of	of	ADP
fnp-3528	1539	43	the	the	DET
fnp-3528	1539	44	abca3	abca3	PROPN
fnp-3528	1539	45	gene	gene	NOUN
fnp-3528	1539	46	.	.	PUNCT
fnp-3528	1540	1	ann	ann	PROPN
fnp-3528	1540	2	anat	anat	PROPN
fnp-3528	1540	3	2017	2017	NUM
fnp-3528	1540	4	,	,	PUNCT
fnp-3528	1540	5	210	210	NUM
fnp-3528	1540	6	,	,	PUNCT
fnp-3528	1540	7	135	135	NUM
fnp-3528	1540	8	-	-	SYM
fnp-3528	1540	9	46	46	NUM
fnp-3528	1540	10	.	.	PUNCT
fnp-3528	1541	1	weng	weng	PROPN
fnp-3528	1541	2	,	,	PUNCT
fnp-3528	1541	3	j.	j.	PROPN
fnp-3528	1541	4	;	;	PUNCT
fnp-3528	1541	5	mata	mata	PROPN
fnp-3528	1541	6	,	,	PUNCT
fnp-3528	1541	7	n.	n.	PROPN
fnp-3528	1541	8	l.	l.	PROPN
fnp-3528	1541	9	;	;	PUNCT
fnp-3528	1541	10	azarian	azarian	NOUN
fnp-3528	1541	11	,	,	PUNCT
fnp-3528	1541	12	s.	s.	PROPN
fnp-3528	1541	13	m.	m.	PROPN
fnp-3528	1541	14	;	;	PUNCT
fnp-3528	1541	15	tzekov	tzekov	PROPN
fnp-3528	1541	16	,	,	PUNCT
fnp-3528	1541	17	r.	r.	PROPN
fnp-3528	1541	18	t.	t.	PROPN
fnp-3528	1541	19	;	;	PUNCT
fnp-3528	1541	20	birch	birch	PROPN
fnp-3528	1541	21	,	,	PUNCT
fnp-3528	1541	22	d.	d.	PROPN
fnp-3528	1541	23	g.	g.	PROPN
fnp-3528	1541	24	;	;	PUNCT
fnp-3528	1541	25	travis	travis	PROPN
fnp-3528	1541	26	,	,	PUNCT
fnp-3528	1541	27	g.	g.	PROPN
fnp-3528	1541	28	h.	h.	PROPN
fnp-3528	1541	29	insights	insight	NOUN
fnp-3528	1541	30	into	into	ADP
fnp-3528	1541	31	the	the	DET
fnp-3528	1541	32	function	function	NOUN
fnp-3528	1541	33	of	of	ADP
fnp-3528	1541	34	rim	rim	NOUN
fnp-3528	1541	35	protein	protein	NOUN
fnp-3528	1541	36	in	in	ADP
fnp-3528	1541	37	photoreceptors	photoreceptor	NOUN
fnp-3528	1541	38	and	and	CCONJ
fnp-3528	1541	39	etiology	etiology	NOUN
fnp-3528	1541	40	of	of	ADP
fnp-3528	1541	41	stargardt	stargardt	PROPN
fnp-3528	1541	42	's	's	PART
fnp-3528	1541	43	disease	disease	NOUN
fnp-3528	1541	44	from	from	ADP
fnp-3528	1541	45	the	the	DET
fnp-3528	1541	46	phenotype	phenotype	NOUN
fnp-3528	1541	47	in	in	ADP
fnp-3528	1541	48	abcr	abcr	NOUN
fnp-3528	1541	49	knockout	knockout	NOUN
fnp-3528	1541	50	mice	mouse	NOUN
fnp-3528	1541	51	.	.	PUNCT
fnp-3528	1542	1	cell	cell	NOUN
fnp-3528	1542	2	1999	1999	NUM
fnp-3528	1542	3	,	,	PUNCT
fnp-3528	1542	4	98	98	NUM
fnp-3528	1542	5	,	,	PUNCT
fnp-3528	1542	6	13	13	NUM
fnp-3528	1542	7	-	-	SYM
fnp-3528	1542	8	23	23	NUM
fnp-3528	1542	9	.	.	PUNCT
fnp-3528	1543	1	molday	molday	PROPN
fnp-3528	1543	2	,	,	PUNCT
fnp-3528	1543	3	r.	r.	PROPN
fnp-3528	1543	4	s.	s.	PROPN
fnp-3528	1543	5	atp	atp	PROPN
fnp-3528	1543	6	-	-	PUNCT
fnp-3528	1543	7	binding	bind	VERB
fnp-3528	1543	8	cassette	cassette	NOUN
fnp-3528	1543	9	transporter	transporter	NOUN
fnp-3528	1543	10	abca4	abca4	ADJ
fnp-3528	1543	11	:	:	PUNCT
fnp-3528	1543	12	molecular	molecular	ADJ
fnp-3528	1543	13	properties	property	NOUN
fnp-3528	1543	14	and	and	CCONJ
fnp-3528	1543	15	role	role	NOUN
fnp-3528	1543	16	in	in	ADP
fnp-3528	1543	17	vision	vision	NOUN
fnp-3528	1543	18	and	and	CCONJ
fnp-3528	1543	19	macular	macular	ADJ
fnp-3528	1543	20	degeneration	degeneration	NOUN
fnp-3528	1543	21	.	.	PUNCT
fnp-3528	1544	1	j	j	PROPN
fnp-3528	1544	2	bioenerg	bioenerg	PROPN
fnp-3528	1544	3	biomembr	biomembr	VERB
fnp-3528	1544	4	2007	2007	NUM
fnp-3528	1544	5	,	,	PUNCT
fnp-3528	1544	6	39	39	NUM
fnp-3528	1544	7	,	,	PUNCT
fnp-3528	1544	8	507	507	NUM
fnp-3528	1544	9	-	-	SYM
fnp-3528	1544	10	17	17	NUM
fnp-3528	1544	11	.	.	PUNCT
fnp-3528	1545	1	trigueros	triguero	NOUN
fnp-3528	1545	2	-	-	PUNCT
fnp-3528	1545	3	motos	motos	PROPN
fnp-3528	1545	4	,	,	PUNCT
fnp-3528	1545	5	l.	l.	PROPN
fnp-3528	1545	6	;	;	PUNCT
fnp-3528	1545	7	van	van	PROPN
fnp-3528	1545	8	capelleveen	capelleveen	PROPN
fnp-3528	1545	9	,	,	PUNCT
fnp-3528	1545	10	j.	j.	PROPN
fnp-3528	1545	11	c.	c.	PROPN
fnp-3528	1545	12	;	;	PUNCT
fnp-3528	1545	13	torta	torta	PROPN
fnp-3528	1545	14	,	,	PUNCT
fnp-3528	1545	15	f.	f.	PROPN
fnp-3528	1545	16	;	;	PUNCT
fnp-3528	1545	17	castaño	castaño	PROPN
fnp-3528	1545	18	,	,	PUNCT
fnp-3528	1545	19	d.	d.	PROPN
fnp-3528	1545	20	;	;	PUNCT
fnp-3528	1545	21	zhang	zhang	PROPN
fnp-3528	1545	22	,	,	PUNCT
fnp-3528	1545	23	l.	l.	PROPN
fnp-3528	1545	24	h.	h.	PROPN
fnp-3528	1545	25	;	;	PUNCT
fnp-3528	1545	26	chai	chai	NOUN
fnp-3528	1545	27	,	,	PUNCT
fnp-3528	1545	28	e.	e.	PROPN
fnp-3528	1545	29	c.	c.	PROPN
fnp-3528	1545	30	;	;	PUNCT
fnp-3528	1545	31	kang	kang	PROPN
fnp-3528	1545	32	,	,	PUNCT
fnp-3528	1545	33	m.	m.	NOUN
fnp-3528	1545	34	;	;	PUNCT
fnp-3528	1545	35	dimova	dimova	PROPN
fnp-3528	1545	36	,	,	PUNCT
fnp-3528	1545	37	l.	l.	PROPN
fnp-3528	1545	38	g.	g.	PROPN
fnp-3528	1545	39	;	;	PUNCT
fnp-3528	1545	40	schimmel	schimmel	PROPN
fnp-3528	1545	41	,	,	PUNCT
fnp-3528	1545	42	a.	a.	PROPN
fnp-3528	1545	43	w.	w.	PROPN
fnp-3528	1545	44	m.	m.	PROPN
fnp-3528	1545	45	;	;	PUNCT
fnp-3528	1545	46	tietjen	tietjen	NOUN
fnp-3528	1545	47	,	,	PUNCT
fnp-3528	1545	48	i.	i.	NOUN
fnp-3528	1545	49	;	;	PUNCT
fnp-3528	1545	50	radomski	radomski	ADJ
fnp-3528	1545	51	,	,	PUNCT
fnp-3528	1545	52	c.	c.	PROPN
fnp-3528	1545	53	;	;	PUNCT
fnp-3528	1545	54	tan	tan	PROPN
fnp-3528	1545	55	,	,	PUNCT
fnp-3528	1545	56	l.	l.	PROPN
fnp-3528	1545	57	j.	j.	PROPN
fnp-3528	1545	58	;	;	PUNCT
fnp-3528	1545	59	thiam	thiam	PROPN
fnp-3528	1545	60	,	,	PUNCT
fnp-3528	1545	61	c.	c.	PROPN
fnp-3528	1545	62	h.	h.	PROPN
fnp-3528	1545	63	;	;	PUNCT
fnp-3528	1545	64	narayanaswamy	narayanaswamy	NOUN
fnp-3528	1545	65	,	,	PUNCT
fnp-3528	1545	66	p.	p.	PROPN
fnp-3528	1545	67	;	;	PUNCT
fnp-3528	1545	68	wu	wu	PROPN
fnp-3528	1545	69	,	,	PUNCT
fnp-3528	1545	70	d.	d.	PROPN
fnp-3528	1545	71	h.	h.	PROPN
fnp-3528	1545	72	;	;	PUNCT
fnp-3528	1545	73	dorninger	dorninger	PROPN
fnp-3528	1545	74	,	,	PUNCT
fnp-3528	1545	75	f.	f.	PROPN
fnp-3528	1545	76	;	;	PUNCT
fnp-3528	1545	77	yakala	yakala	PROPN
fnp-3528	1545	78	,	,	PUNCT
fnp-3528	1545	79	g.	g.	PROPN
fnp-3528	1545	80	k.	k.	PROPN
fnp-3528	1545	81	;	;	PUNCT
fnp-3528	1545	82	barhdadi	barhdadi	NOUN
fnp-3528	1545	83	,	,	PUNCT
fnp-3528	1545	84	a.	a.	NOUN
fnp-3528	1545	85	;	;	PUNCT
fnp-3528	1545	86	angeli	angeli	PROPN
fnp-3528	1545	87	,	,	PUNCT
fnp-3528	1546	1	v.	v.	ADP
fnp-3528	1546	2	;	;	PUNCT
fnp-3528	1546	3	dubé	dubé	NOUN
fnp-3528	1546	4	,	,	PUNCT
fnp-3528	1546	5	m.	m.	NOUN
fnp-3528	1546	6	p.	p.	NOUN
fnp-3528	1546	7	;	;	PUNCT
fnp-3528	1547	1	berger	berger	PROPN
fnp-3528	1547	2	,	,	PUNCT
fnp-3528	1547	3	j.	j.	PROPN
fnp-3528	1547	4	;	;	PUNCT
fnp-3528	1547	5	dallinga	dallinga	NOUN
fnp-3528	1547	6	-	-	PUNCT
fnp-3528	1547	7	thie	thie	NOUN
fnp-3528	1547	8	,	,	PUNCT
fnp-3528	1547	9	g.	g.	PROPN
fnp-3528	1547	10	m.	m.	PROPN
fnp-3528	1547	11	;	;	PUNCT
fnp-3528	1547	12	tietge	tietge	VERB
fnp-3528	1547	13	,	,	PUNCT
fnp-3528	1547	14	u.	u.	PROPN
fnp-3528	1547	15	j.	j.	PROPN
fnp-3528	1547	16	f.	f.	PROPN
fnp-3528	1547	17	;	;	PUNCT
fnp-3528	1547	18	wenk	wenk	PROPN
fnp-3528	1547	19	,	,	PUNCT
fnp-3528	1547	20	m.	m.	PROPN
fnp-3528	1547	21	r.	r.	PROPN
fnp-3528	1547	22	;	;	PUNCT
fnp-3528	1547	23	hayden	hayden	PROPN
fnp-3528	1547	24	,	,	PUNCT
fnp-3528	1547	25	m.	m.	NOUN
fnp-3528	1547	26	r.	r.	PROPN
fnp-3528	1547	27	;	;	PUNCT
fnp-3528	1547	28	hovingh	hovingh	ADV
fnp-3528	1547	29	,	,	PUNCT
fnp-3528	1547	30	g.	g.	PROPN
fnp-3528	1547	31	k.	k.	PROPN
fnp-3528	1547	32	;	;	PUNCT
fnp-3528	1547	33	singaraja	singaraja	PROPN
fnp-3528	1547	34	,	,	PUNCT
fnp-3528	1547	35	r.	r.	PROPN
fnp-3528	1547	36	r.	r.	PROPN
fnp-3528	1547	37	abca8	abca8	PROPN
fnp-3528	1547	38	regulates	regulate	VERB
fnp-3528	1547	39	cholesterol	cholesterol	NOUN
fnp-3528	1547	40	efflux	efflux	NOUN
fnp-3528	1547	41	and	and	CCONJ
fnp-3528	1547	42	high	high	ADJ
fnp-3528	1547	43	-	-	PUNCT
fnp-3528	1547	44	density	density	NOUN
fnp-3528	1547	45	lipoprotein	lipoprotein	ADJ
fnp-3528	1547	46	cholesterol	cholesterol	NOUN
fnp-3528	1547	47	levels	level	NOUN
fnp-3528	1547	48	.	.	PUNCT
fnp-3528	1548	1	arterioscler	arterioscler	PROPN
fnp-3528	1548	2	thromb	thromb	PROPN
fnp-3528	1548	3	vasc	vasc	PROPN
fnp-3528	1548	4	biol	biol	PROPN
fnp-3528	1548	5	2017	2017	NUM
fnp-3528	1548	6	,	,	PUNCT
fnp-3528	1548	7	37	37	NUM
fnp-3528	1548	8	,	,	PUNCT
fnp-3528	1548	9	2147	2147	NUM
fnp-3528	1548	10	-	-	SYM
fnp-3528	1548	11	55	55	NUM
fnp-3528	1548	12	.	.	PUNCT
fnp-3528	1549	1	iritani	iritani	PROPN
fnp-3528	1549	2	,	,	PUNCT
fnp-3528	1549	3	s.	s.	PROPN
fnp-3528	1549	4	;	;	PUNCT
fnp-3528	1549	5	torii	torii	PROPN
fnp-3528	1549	6	,	,	PUNCT
fnp-3528	1549	7	y.	y.	NOUN
fnp-3528	1549	8	;	;	PUNCT
fnp-3528	1549	9	habuchi	habuchi	PROPN
fnp-3528	1549	10	,	,	PUNCT
fnp-3528	1549	11	c.	c.	PROPN
fnp-3528	1549	12	;	;	PUNCT
fnp-3528	1549	13	sekiguchi	sekiguchi	PROPN
fnp-3528	1549	14	,	,	PUNCT
fnp-3528	1549	15	h.	h.	PROPN
fnp-3528	1549	16	;	;	PUNCT
fnp-3528	1549	17	fujishiro	fujishiro	PROPN
fnp-3528	1549	18	,	,	PUNCT
fnp-3528	1549	19	h.	h.	PROPN
fnp-3528	1549	20	;	;	PUNCT
fnp-3528	1549	21	yoshida	yoshida	PROPN
fnp-3528	1549	22	,	,	PUNCT
fnp-3528	1549	23	m.	m.	NOUN
fnp-3528	1549	24	;	;	PUNCT
fnp-3528	1549	25	go	go	VERB
fnp-3528	1549	26	,	,	PUNCT
fnp-3528	1549	27	y.	y.	PROPN
fnp-3528	1549	28	;	;	PUNCT
fnp-3528	1549	29	iriki	iriki	PROPN
fnp-3528	1549	30	,	,	PUNCT
fnp-3528	1549	31	a.	a.	NOUN
fnp-3528	1549	32	;	;	PUNCT
fnp-3528	1549	33	isoda	isoda	PROPN
fnp-3528	1549	34	,	,	PUNCT
fnp-3528	1549	35	m.	m.	NOUN
fnp-3528	1549	36	;	;	PUNCT
fnp-3528	1549	37	ozaki	ozaki	PROPN
fnp-3528	1549	38	,	,	PUNCT
fnp-3528	1549	39	n.	n.	VERB
fnp-3528	1549	40	the	the	DET
fnp-3528	1549	41	neuropathological	neuropathological	ADJ
fnp-3528	1549	42	investigation	investigation	NOUN
fnp-3528	1549	43	of	of	ADP
fnp-3528	1549	44	the	the	DET
fnp-3528	1549	45	brain	brain	NOUN
fnp-3528	1549	46	in	in	ADP
fnp-3528	1549	47	a	a	DET
fnp-3528	1549	48	monkey	monkey	NOUN
fnp-3528	1549	49	model	model	NOUN
fnp-3528	1549	50	of	of	ADP
fnp-3528	1549	51	autism	autism	NOUN
fnp-3528	1549	52	spectrum	spectrum	NOUN
fnp-3528	1549	53	disorder	disorder	NOUN
fnp-3528	1549	54	with	with	ADP
fnp-3528	1549	55	abca13	abca13	NOUN
fnp-3528	1549	56	deletion	deletion	NOUN
fnp-3528	1549	57	.	.	PUNCT
fnp-3528	1550	1	int	int	PROPN
fnp-3528	1550	2	j	j	PROPN
fnp-3528	1550	3	dev	dev	PROPN
fnp-3528	1550	4	neurosci	neurosci	PROPN
fnp-3528	1550	5	2018	2018	NUM
fnp-3528	1550	6	,	,	PUNCT
fnp-3528	1550	7	71	71	NUM
fnp-3528	1550	8	,	,	PUNCT
fnp-3528	1550	9	130	130	NUM
fnp-3528	1550	10	-	-	SYM
fnp-3528	1550	11	9	9	NUM
fnp-3528	1550	12	.	.	PUNCT
fnp-3528	1551	1	lepage	lepage	PROPN
fnp-3528	1551	2	,	,	PUNCT
fnp-3528	1551	3	d.	d.	PROPN
fnp-3528	1551	4	f.	f.	PROPN
fnp-3528	1551	5	;	;	PUNCT
fnp-3528	1551	6	conlon	conlon	PROPN
fnp-3528	1551	7	,	,	PUNCT
fnp-3528	1551	8	r.	r.	PROPN
fnp-3528	1551	9	a.	a.	PROPN
fnp-3528	1551	10	animal	animal	NOUN
fnp-3528	1551	11	models	model	NOUN
fnp-3528	1551	12	for	for	ADP
fnp-3528	1551	13	disease	disease	NOUN
fnp-3528	1551	14	:	:	PUNCT
fnp-3528	1551	15	knockout	knockout	NOUN
fnp-3528	1551	16	,	,	PUNCT
fnp-3528	1551	17	knock	knock	NOUN
fnp-3528	1551	18	-	-	PUNCT
fnp-3528	1551	19	in	in	NOUN
fnp-3528	1551	20	,	,	PUNCT
fnp-3528	1551	21	and	and	CCONJ
fnp-3528	1551	22	conditional	conditional	ADJ
fnp-3528	1551	23	mutant	mutant	ADJ
fnp-3528	1551	24	mice	mouse	NOUN
fnp-3528	1551	25	.	.	PUNCT
fnp-3528	1552	1	methods	method	NOUN
fnp-3528	1552	2	mol	mol	ADP
fnp-3528	1552	3	med	med	PROPN
fnp-3528	1552	4	2006	2006	NUM
fnp-3528	1552	5	,	,	PUNCT
fnp-3528	1552	6	129	129	NUM
fnp-3528	1552	7	,	,	PUNCT
fnp-3528	1552	8	41	41	NUM
fnp-3528	1552	9	-	-	SYM
fnp-3528	1552	10	67	67	NUM
fnp-3528	1552	11	.	.	PUNCT
fnp-3528	1553	1	navabpour	navabpour	PROPN
fnp-3528	1553	2	,	,	PUNCT
fnp-3528	1553	3	s.	s.	PROPN
fnp-3528	1553	4	;	;	PUNCT
fnp-3528	1553	5	kwapis	kwapis	PROPN
fnp-3528	1553	6	,	,	PUNCT
fnp-3528	1553	7	j.	j.	PROPN
fnp-3528	1553	8	l.	l.	PROPN
fnp-3528	1553	9	;	;	PUNCT
fnp-3528	1553	10	jarome	jarome	PROPN
fnp-3528	1553	11	,	,	PUNCT
fnp-3528	1553	12	t.	t.	PROPN
fnp-3528	1553	13	j.	j.	PROPN
fnp-3528	1553	14	a	a	DET
fnp-3528	1553	15	neuroscientist	neuroscientist	NOUN
fnp-3528	1553	16	's	's	PART
fnp-3528	1553	17	guide	guide	NOUN
fnp-3528	1553	18	to	to	AUX
fnp-3528	1553	19	transgenic	transgenic	VERB
fnp-3528	1553	20	mice	mouse	NOUN
fnp-3528	1553	21	and	and	CCONJ
fnp-3528	1553	22	other	other	ADJ
fnp-3528	1553	23	genetic	genetic	ADJ
fnp-3528	1553	24	tools	tool	NOUN
fnp-3528	1553	25	.	.	PUNCT
fnp-3528	1554	1	neurosci	neurosci	PROPN
fnp-3528	1554	2	biobehav	biobehav	PROPN
fnp-3528	1554	3	rev	rev	VERB
fnp-3528	1554	4	2020	2020	NUM
fnp-3528	1554	5	,	,	PUNCT
fnp-3528	1554	6	108	108	NUM
fnp-3528	1554	7	,	,	PUNCT
fnp-3528	1554	8	732	732	NUM
fnp-3528	1554	9	-	-	SYM
fnp-3528	1554	10	48	48	NUM
fnp-3528	1554	11	.	.	PUNCT
fnp-3528	1555	1	campenhout	campenhout	PROPN
fnp-3528	1555	2	,	,	PUNCT
fnp-3528	1555	3	c.	c.	PROPN
fnp-3528	1555	4	v.	v.	PROPN
fnp-3528	1555	5	;	;	PUNCT
fnp-3528	1555	6	cabochette	cabochette	NOUN
fnp-3528	1555	7	,	,	PUNCT
fnp-3528	1555	8	p.	p.	NOUN
fnp-3528	1555	9	;	;	PUNCT
fnp-3528	1555	10	veillard	veillard	PROPN
fnp-3528	1555	11	,	,	PUNCT
fnp-3528	1555	12	a.	a.	PROPN
fnp-3528	1555	13	c.	c.	PROPN
fnp-3528	1555	14	;	;	PUNCT
fnp-3528	1555	15	laczik	laczik	NOUN
fnp-3528	1555	16	,	,	PUNCT
fnp-3528	1555	17	m.	m.	NOUN
fnp-3528	1555	18	;	;	PUNCT
fnp-3528	1555	19	zelisko	zelisko	ADJ
fnp-3528	1555	20	-	-	PUNCT
fnp-3528	1555	21	schmidt	schmidt	ADJ
fnp-3528	1555	22	,	,	PUNCT
fnp-3528	1555	23	a.	a.	NOUN
fnp-3528	1555	24	;	;	PUNCT
fnp-3528	1555	25	sabatel	sabatel	PROPN
fnp-3528	1555	26	,	,	PUNCT
fnp-3528	1555	27	c.	c.	PROPN
fnp-3528	1555	28	;	;	PUNCT
fnp-3528	1555	29	dhainaut	dhainaut	PROPN
fnp-3528	1555	30	,	,	PUNCT
fnp-3528	1555	31	m.	m.	NOUN
fnp-3528	1555	32	;	;	PUNCT
fnp-3528	1555	33	vanhollebeke	vanhollebeke	ADJ
fnp-3528	1555	34	,	,	PUNCT
fnp-3528	1555	35	b.	b.	PROPN
fnp-3528	1555	36	;	;	PUNCT
fnp-3528	1555	37	gueydan	gueydan	PROPN
fnp-3528	1555	38	,	,	PUNCT
fnp-3528	1555	39	c.	c.	PROPN
fnp-3528	1555	40	;	;	PUNCT
fnp-3528	1555	41	kruys	kruy	NOUN
fnp-3528	1555	42	,	,	PUNCT
fnp-3528	1555	43	v.	v.	ADP
fnp-3528	1555	44	guidelines	guideline	NOUN
fnp-3528	1555	45	for	for	ADP
fnp-3528	1555	46	optimized	optimize	VERB
fnp-3528	1555	47	gene	gene	NOUN
fnp-3528	1555	48	knockout	knockout	NOUN
fnp-3528	1555	49	using	use	VERB
fnp-3528	1555	50	crispr	crispr	ADJ
fnp-3528	1555	51	/	/	SYM
fnp-3528	1555	52	cas9	cas9	NOUN
fnp-3528	1555	53	.	.	PUNCT
fnp-3528	1556	1	biotechniques	biotechnique	NOUN
fnp-3528	1556	2	2019	2019	NUM
fnp-3528	1556	3	,	,	PUNCT
fnp-3528	1556	4	66	66	NUM
fnp-3528	1556	5	,	,	PUNCT
fnp-3528	1556	6	295	295	NUM
fnp-3528	1556	7	-	-	SYM
fnp-3528	1556	8	302	302	NUM
fnp-3528	1556	9	.	.	PUNCT
fnp-3528	1557	1	lovett	lovett	PROPN
fnp-3528	1557	2	-	-	PUNCT
fnp-3528	1557	3	racke	racke	PROPN
fnp-3528	1557	4	,	,	PUNCT
fnp-3528	1557	5	a.	a.	PROPN
fnp-3528	1557	6	e.	e.	PROPN
fnp-3528	1557	7	;	;	PUNCT
fnp-3528	1557	8	cravens	craven	NOUN
fnp-3528	1557	9	,	,	PUNCT
fnp-3528	1557	10	p.	p.	PROPN
fnp-3528	1557	11	d.	d.	PROPN
fnp-3528	1557	12	;	;	PUNCT
fnp-3528	1558	1	gocke	gocke	PROPN
fnp-3528	1558	2	,	,	PUNCT
fnp-3528	1558	3	a.	a.	PROPN
fnp-3528	1558	4	r.	r.	PROPN
fnp-3528	1558	5	;	;	PUNCT
fnp-3528	1558	6	racke	racke	PROPN
fnp-3528	1558	7	,	,	PUNCT
fnp-3528	1558	8	m.	m.	NOUN
fnp-3528	1558	9	k.	k.	PROPN
fnp-3528	1558	10	;	;	PUNCT
fnp-3528	1558	11	stüve	stüve	NOUN
fnp-3528	1558	12	,	,	PUNCT
fnp-3528	1558	13	o.	o.	NOUN
fnp-3528	1558	14	therapeutic	therapeutic	ADJ
fnp-3528	1558	15	potential	potential	NOUN
fnp-3528	1558	16	of	of	ADP
fnp-3528	1558	17	small	small	ADJ
fnp-3528	1558	18	interfering	interfere	VERB
fnp-3528	1558	19	rna	rna	NOUN
fnp-3528	1558	20	for	for	ADP
fnp-3528	1558	21	central	central	ADJ
fnp-3528	1558	22	nervous	nervous	ADJ
fnp-3528	1558	23	system	system	NOUN
fnp-3528	1558	24	diseases	disease	NOUN
fnp-3528	1558	25	.	.	PUNCT
fnp-3528	1559	1	arch	arch	ADJ
fnp-3528	1559	2	neurol	neurol	NOUN
fnp-3528	1559	3	2005	2005	NUM
fnp-3528	1559	4	,	,	PUNCT
fnp-3528	1559	5	62	62	NUM
fnp-3528	1559	6	,	,	PUNCT
fnp-3528	1559	7	1810	1810	NUM
fnp-3528	1559	8	-	-	SYM
fnp-3528	1559	9	3	3	NUM
fnp-3528	1559	10	.	.	X
fnp-3528	1559	11	moore	moore	PROPN
fnp-3528	1559	12	,	,	PUNCT
fnp-3528	1559	13	c.	c.	PROPN
fnp-3528	1559	14	b.	b.	PROPN
fnp-3528	1559	15	;	;	PUNCT
fnp-3528	1559	16	guthrie	guthrie	PROPN
fnp-3528	1559	17	,	,	PUNCT
fnp-3528	1559	18	e.	e.	PROPN
fnp-3528	1559	19	h.	h.	PROPN
fnp-3528	1559	20	;	;	PUNCT
fnp-3528	1559	21	huang	huang	PROPN
fnp-3528	1559	22	,	,	PUNCT
fnp-3528	1559	23	m.	m.	NOUN
fnp-3528	1559	24	t.	t.	PROPN
fnp-3528	1559	25	;	;	PUNCT
fnp-3528	1559	26	taxman	taxman	NOUN
fnp-3528	1559	27	,	,	PUNCT
fnp-3528	1559	28	d.	d.	PROPN
fnp-3528	1559	29	j.	j.	PROPN
fnp-3528	1560	1	short	short	PROPN
fnp-3528	1560	2	hairpin	hairpin	PROPN
fnp-3528	1560	3	rna	rna	NOUN
fnp-3528	1560	4	(	(	PUNCT
fnp-3528	1560	5	shrna	shrna	NOUN
fnp-3528	1560	6	):	):	PUNCT
fnp-3528	1560	7	design	design	NOUN
fnp-3528	1560	8	,	,	PUNCT
fnp-3528	1560	9	delivery	delivery	NOUN
fnp-3528	1560	10	,	,	PUNCT
fnp-3528	1560	11	and	and	CCONJ
fnp-3528	1560	12	assessment	assessment	NOUN
fnp-3528	1560	13	of	of	ADP
fnp-3528	1560	14	gene	gene	NOUN
fnp-3528	1560	15	knockdown	knockdown	NOUN
fnp-3528	1560	16	.	.	PUNCT
fnp-3528	1561	1	methods	method	NOUN
fnp-3528	1561	2	mol	mol	ADP
fnp-3528	1561	3	biol	biol	PROPN
fnp-3528	1561	4	(	(	PUNCT
fnp-3528	1561	5	clifton	clifton	PROPN
fnp-3528	1561	6	,	,	PUNCT
fnp-3528	1561	7	n.j	n.j	PROPN
fnp-3528	1561	8	)	)	PUNCT
fnp-3528	1561	9	2010	2010	NUM
fnp-3528	1561	10	,	,	PUNCT
fnp-3528	1561	11	629	629	NUM
fnp-3528	1561	12	,	,	PUNCT
fnp-3528	1561	13	141	141	NUM
fnp-3528	1561	14	-	-	SYM
fnp-3528	1561	15	58	58	NUM
fnp-3528	1561	16	.	.	PUNCT
fnp-3528	1562	1	drummond	drummond	PROPN
fnp-3528	1562	2	,	,	PUNCT
fnp-3528	1562	3	e.	e.	PROPN
fnp-3528	1562	4	;	;	PUNCT
fnp-3528	1562	5	wisniewski	wisniewski	PROPN
fnp-3528	1562	6	,	,	PUNCT
fnp-3528	1562	7	t.	t.	PROPN
fnp-3528	1562	8	alzheimer	alzheimer	PROPN
fnp-3528	1562	9	's	's	PART
fnp-3528	1562	10	disease	disease	NOUN
fnp-3528	1562	11	:	:	PUNCT
fnp-3528	1562	12	experimental	experimental	ADJ
fnp-3528	1562	13	models	model	NOUN
fnp-3528	1562	14	and	and	CCONJ
fnp-3528	1562	15	reality	reality	NOUN
fnp-3528	1562	16	.	.	PUNCT
fnp-3528	1563	1	acta	acta	PROPN
fnp-3528	1563	2	neuropathol	neuropathol	PROPN
fnp-3528	1563	3	2017	2017	NUM
fnp-3528	1563	4	,	,	PUNCT
fnp-3528	1563	5	133	133	NUM
fnp-3528	1563	6	,	,	PUNCT
fnp-3528	1563	7	155	155	NUM
fnp-3528	1563	8	-	-	SYM
fnp-3528	1563	9	75	75	NUM
fnp-3528	1563	10	.	.	PUNCT
fnp-3528	1564	1	mochizuki	mochizuki	PROPN
fnp-3528	1564	2	,	,	PUNCT
fnp-3528	1564	3	h.	h.	PROPN
fnp-3528	1564	4	;	;	PUNCT
fnp-3528	1564	5	yamada	yamada	PROPN
fnp-3528	1564	6	,	,	PUNCT
fnp-3528	1564	7	m.	m.	NOUN
fnp-3528	1564	8	;	;	PUNCT
fnp-3528	1564	9	mizuno	mizuno	PROPN
fnp-3528	1564	10	,	,	PUNCT
fnp-3528	1564	11	y.	y.	PROPN
fnp-3528	1564	12	alpha	alpha	PROPN
fnp-3528	1564	13	-	-	PUNCT
fnp-3528	1564	14	synuclein	synuclein	NOUN
fnp-3528	1564	15	overexpression	overexpression	NOUN
fnp-3528	1564	16	model	model	NOUN
fnp-3528	1564	17	.	.	PUNCT
fnp-3528	1565	1	j	j	PROPN
fnp-3528	1565	2	neural	neural	ADJ
fnp-3528	1565	3	transm	transm	PROPN
fnp-3528	1565	4	2006	2006	NUM
fnp-3528	1565	5	,	,	PUNCT
fnp-3528	1565	6	281	281	NUM
fnp-3528	1565	7	-	-	SYM
fnp-3528	1565	8	4	4	NUM
fnp-3528	1565	9	.	.	PUNCT
fnp-3528	1566	1	peltz	peltz	PROPN
fnp-3528	1566	2	,	,	PUNCT
fnp-3528	1566	3	g.	g.	PROPN
fnp-3528	1566	4	can	can	AUX
fnp-3528	1566	5	'	'	PUNCT
fnp-3528	1566	6	humanized	humanize	VERB
fnp-3528	1566	7	'	'	PUNCT
fnp-3528	1566	8	mice	mouse	NOUN
fnp-3528	1566	9	improve	improve	VERB
fnp-3528	1566	10	drug	drug	NOUN
fnp-3528	1566	11	development	development	NOUN
fnp-3528	1566	12	in	in	ADP
fnp-3528	1566	13	the	the	DET
fnp-3528	1566	14	21st	21st	ADJ
fnp-3528	1566	15	century	century	NOUN
fnp-3528	1566	16	?	?	PUNCT
fnp-3528	1567	1	trends	trend	NOUN
fnp-3528	1567	2	pharmacol	pharmacol	PROPN
fnp-3528	1567	3	sci	sci	PROPN
fnp-3528	1567	4	2013	2013	NUM
fnp-3528	1567	5	,	,	PUNCT
fnp-3528	1567	6	34	34	NUM
fnp-3528	1567	7	,	,	PUNCT
fnp-3528	1567	8	255	255	NUM
fnp-3528	1567	9	-	-	SYM
fnp-3528	1567	10	60	60	NUM
fnp-3528	1567	11	.	.	PUNCT
fnp-3528	1568	1	krohn	krohn	PROPN
fnp-3528	1568	2	,	,	PUNCT
fnp-3528	1568	3	m.	m.	NOUN
fnp-3528	1568	4	;	;	PUNCT
fnp-3528	1568	5	zoufal	zoufal	NOUN
fnp-3528	1568	6	,	,	PUNCT
fnp-3528	1568	7	v.	v.	ADP
fnp-3528	1568	8	;	;	PUNCT
fnp-3528	1568	9	mairinger	mairinger	NOUN
fnp-3528	1568	10	,	,	PUNCT
fnp-3528	1568	11	s.	s.	PROPN
fnp-3528	1568	12	;	;	PUNCT
fnp-3528	1568	13	wanek	wanek	ADV
fnp-3528	1568	14	,	,	PUNCT
fnp-3528	1568	15	t.	t.	PROPN
fnp-3528	1568	16	;	;	PUNCT
fnp-3528	1568	17	paarmann	paarmann	PROPN
fnp-3528	1568	18	,	,	PUNCT
fnp-3528	1568	19	k.	k.	PROPN
fnp-3528	1568	20	;	;	PUNCT
fnp-3528	1568	21	brüning	brüne	VERB
fnp-3528	1568	22	,	,	PUNCT
fnp-3528	1568	23	t.	t.	PROPN
fnp-3528	1568	24	;	;	PUNCT
fnp-3528	1568	25	eiriz	eiriz	NOUN
fnp-3528	1568	26	,	,	PUNCT
fnp-3528	1568	27	i.	i.	NOUN
fnp-3528	1568	28	;	;	PUNCT
fnp-3528	1568	29	brackhan	brackhan	PROPN
fnp-3528	1568	30	,	,	PUNCT
fnp-3528	1568	31	m.	m.	NOUN
fnp-3528	1568	32	;	;	PUNCT
fnp-3528	1568	33	langer	langer	NOUN
fnp-3528	1568	34	,	,	PUNCT
fnp-3528	1568	35	o.	o.	PROPN
fnp-3528	1568	36	;	;	PUNCT
fnp-3528	1568	37	pahnke	pahnke	PROPN
fnp-3528	1568	38	,	,	PUNCT
fnp-3528	1568	39	j.	j.	PROPN
fnp-3528	1568	40	generation	generation	NOUN
fnp-3528	1568	41	and	and	CCONJ
fnp-3528	1568	42	characterization	characterization	NOUN
fnp-3528	1568	43	of	of	ADP
fnp-3528	1568	44	an	an	DET
fnp-3528	1568	45	abcc1	abcc1	PROPN
fnp-3528	1568	46	humanized	humanize	VERB
fnp-3528	1568	47	mouse	mouse	NOUN
fnp-3528	1568	48	model	model	NOUN
fnp-3528	1568	49	(	(	PUNCT
fnp-3528	1568	50	habcc1(flx	habcc1(flx	PROPN
fnp-3528	1568	51	/	/	SYM
fnp-3528	1568	52	flx	flx	NOUN
fnp-3528	1568	53	)	)	PUNCT
fnp-3528	1568	54	)	)	PUNCT
fnp-3528	1568	55	with	with	ADP
fnp-3528	1568	56	knockout	knockout	NOUN
fnp-3528	1568	57	capability	capability	NOUN
fnp-3528	1568	58	.	.	PUNCT
fnp-3528	1569	1	mol	mol	ADP
fnp-3528	1569	2	pharmacol	pharmacol	PROPN
fnp-3528	1569	3	2019	2019	NUM
fnp-3528	1569	4	,	,	PUNCT
fnp-3528	1569	5	96	96	NUM
fnp-3528	1569	6	,	,	PUNCT
fnp-3528	1569	7	138	138	NUM
fnp-3528	1569	8	-	-	SYM
fnp-3528	1569	9	147	147	NUM
fnp-3528	1569	10	.	.	PUNCT
fnp-3528	1570	1	dallas	dallas	PROPN
fnp-3528	1570	2	,	,	PUNCT
fnp-3528	1570	3	s.	s.	PROPN
fnp-3528	1570	4	;	;	PUNCT
fnp-3528	1570	5	salphati	salphati	PROPN
fnp-3528	1570	6	,	,	PUNCT
fnp-3528	1570	7	l.	l.	PROPN
fnp-3528	1570	8	;	;	PUNCT
fnp-3528	1570	9	gomez	gomez	PROPN
fnp-3528	1570	10	-	-	PUNCT
fnp-3528	1570	11	zepeda	zepeda	PROPN
fnp-3528	1570	12	,	,	PUNCT
fnp-3528	1570	13	d.	d.	PROPN
fnp-3528	1570	14	;	;	PUNCT
fnp-3528	1570	15	wanek	wanek	ADV
fnp-3528	1570	16	,	,	PUNCT
fnp-3528	1570	17	t.	t.	PROPN
fnp-3528	1570	18	;	;	PUNCT
fnp-3528	1570	19	chen	chen	PROPN
fnp-3528	1570	20	,	,	PUNCT
fnp-3528	1570	21	l.	l.	PROPN
fnp-3528	1570	22	;	;	PUNCT
fnp-3528	1570	23	chu	chu	PROPN
fnp-3528	1570	24	,	,	PUNCT
fnp-3528	1570	25	x.	x.	PROPN
fnp-3528	1570	26	;	;	PUNCT
fnp-3528	1570	27	kunta	kunta	PROPN
fnp-3528	1570	28	,	,	PUNCT
fnp-3528	1570	29	j.	j.	PROPN
fnp-3528	1570	30	;	;	PUNCT
fnp-3528	1570	31	mezler	mezler	NOUN
fnp-3528	1570	32	,	,	PUNCT
fnp-3528	1570	33	m.	m.	NOUN
fnp-3528	1570	34	;	;	PUNCT
fnp-3528	1570	35	menet	menet	NOUN
fnp-3528	1570	36	,	,	PUNCT
fnp-3528	1570	37	m.	m.	NOUN
fnp-3528	1570	38	c.	c.	PROPN
fnp-3528	1570	39	;	;	PUNCT
fnp-3528	1570	40	chasseigneaux	chasseigneaux	PROPN
fnp-3528	1570	41	,	,	PUNCT
fnp-3528	1570	42	s.	s.	PROPN
fnp-3528	1570	43	;	;	PUNCT
fnp-3528	1570	44	decleves	decleve	NOUN
fnp-3528	1570	45	,	,	PUNCT
fnp-3528	1570	46	x.	x.	NOUN
fnp-3528	1570	47	;	;	PUNCT
fnp-3528	1570	48	langer	langer	NOUN
fnp-3528	1570	49	,	,	PUNCT
fnp-3528	1570	50	o.	o.	PROPN
fnp-3528	1570	51	;	;	PUNCT
fnp-3528	1570	52	pierre	pierre	PROPN
fnp-3528	1570	53	,	,	PUNCT
fnp-3528	1570	54	e.	e.	PROPN
fnp-3528	1570	55	;	;	PUNCT
fnp-3528	1570	56	diloreto	diloreto	PROPN
fnp-3528	1570	57	,	,	PUNCT
fnp-3528	1570	58	k.	k.	PROPN
fnp-3528	1570	59	;	;	PUNCT
fnp-3528	1570	60	hoft	hoft	PROPN
fnp-3528	1570	61	,	,	PUNCT
fnp-3528	1570	62	c.	c.	PROPN
fnp-3528	1570	63	;	;	PUNCT
fnp-3528	1570	64	laplanche	laplanche	PROPN
fnp-3528	1570	65	,	,	PUNCT
fnp-3528	1570	66	l.	l.	PROPN
fnp-3528	1570	67	;	;	PUNCT
fnp-3528	1570	68	pang	pang	NOUN
fnp-3528	1570	69	,	,	PUNCT
fnp-3528	1570	70	j.	j.	PROPN
fnp-3528	1570	71	;	;	PUNCT
fnp-3528	1570	72	pereira	pereira	PROPN
fnp-3528	1570	73	,	,	PUNCT
fnp-3528	1570	74	t.	t.	PROPN
fnp-3528	1570	75	;	;	PUNCT
fnp-3528	1570	76	andonian	andonian	PROPN
fnp-3528	1570	77	,	,	PUNCT
fnp-3528	1570	78	c.	c.	PROPN
fnp-3528	1570	79	;	;	PUNCT
fnp-3528	1570	80	simic	simic	PROPN
fnp-3528	1570	81	,	,	PUNCT
fnp-3528	1570	82	d.	d.	PROPN
fnp-3528	1570	83	;	;	PUNCT
fnp-3528	1570	84	rode	ride	VERB
fnp-3528	1570	85	,	,	PUNCT
fnp-3528	1570	86	a.	a.	NOUN
fnp-3528	1570	87	;	;	PUNCT
fnp-3528	1571	1	yabut	yabut	PROPN
fnp-3528	1571	2	,	,	PUNCT
fnp-3528	1571	3	j.	j.	PROPN
fnp-3528	1571	4	;	;	PUNCT
fnp-3528	1571	5	zhang	zhang	PROPN
fnp-3528	1571	6	,	,	PUNCT
fnp-3528	1571	7	x.	x.	PROPN
fnp-3528	1571	8	;	;	PUNCT
fnp-3528	1571	9	scheer	scheer	PROPN
fnp-3528	1571	10	,	,	PUNCT
fnp-3528	1571	11	n.	n.	NOUN
fnp-3528	1571	12	generation	generation	NOUN
fnp-3528	1571	13	and	and	CCONJ
fnp-3528	1571	14	characterization	characterization	NOUN
fnp-3528	1571	15	of	of	ADP
fnp-3528	1571	16	a	a	DET
fnp-3528	1571	17	breast	breast	NOUN
fnp-3528	1571	18	cancer	cancer	NOUN
fnp-3528	1571	19	resistance	resistance	NOUN
fnp-3528	1571	20	protein	protein	NOUN
fnp-3528	1571	21	humanized	humanize	VERB
fnp-3528	1571	22	mouse	mouse	NOUN
fnp-3528	1571	23	model	model	NOUN
fnp-3528	1571	24	.	.	PUNCT
fnp-3528	1572	1	mol	mol	ADP
fnp-3528	1572	2	pharmacol	pharmacol	PROPN
fnp-3528	1572	3	2016	2016	NUM
fnp-3528	1572	4	,	,	PUNCT
fnp-3528	1572	5	89	89	NUM
fnp-3528	1572	6	,	,	PUNCT
fnp-3528	1572	7	492	492	NUM
fnp-3528	1572	8	-	-	SYM
fnp-3528	1572	9	504	504	NUM
fnp-3528	1572	10	.	.	PUNCT
fnp-3528	1573	1	krohn	krohn	PROPN
fnp-3528	1573	2	,	,	PUNCT
fnp-3528	1573	3	m.	m.	NOUN
fnp-3528	1573	4	;	;	PUNCT
fnp-3528	1573	5	wanek	wanek	ADJ
fnp-3528	1573	6	,	,	PUNCT
fnp-3528	1573	7	t.	t.	PROPN
fnp-3528	1573	8	;	;	PUNCT
fnp-3528	1573	9	menet	menet	NOUN
fnp-3528	1573	10	,	,	PUNCT
fnp-3528	1573	11	m.	m.	NOUN
fnp-3528	1573	12	c.	c.	PROPN
fnp-3528	1573	13	;	;	PUNCT
fnp-3528	1573	14	noack	noack	NOUN
fnp-3528	1573	15	,	,	PUNCT
fnp-3528	1573	16	a.	a.	NOUN
fnp-3528	1573	17	;	;	PUNCT
fnp-3528	1573	18	decleves	decleve	NOUN
fnp-3528	1573	19	,	,	PUNCT
fnp-3528	1573	20	x.	x.	NOUN
fnp-3528	1573	21	;	;	PUNCT
fnp-3528	1573	22	langer	langer	NOUN
fnp-3528	1573	23	,	,	PUNCT
fnp-3528	1573	24	o.	o.	PROPN
fnp-3528	1573	25	;	;	PUNCT
fnp-3528	1573	26	loscher	loscher	PROPN
fnp-3528	1573	27	,	,	PUNCT
fnp-3528	1573	28	w.	w.	PROPN
fnp-3528	1573	29	;	;	PUNCT
fnp-3528	1573	30	pahnke	pahnke	PROPN
fnp-3528	1573	31	,	,	PUNCT
fnp-3528	1573	32	j.	j.	PROPN
fnp-3528	1573	33	humanization	humanization	NOUN
fnp-3528	1573	34	of	of	ADP
fnp-3528	1573	35	the	the	DET
fnp-3528	1573	36	blood	blood	NOUN
fnp-3528	1573	37	-	-	PUNCT
fnp-3528	1573	38	brain	brain	NOUN
fnp-3528	1573	39	barrier	barrier	NOUN
fnp-3528	1573	40	transporter	transporter	NOUN
fnp-3528	1573	41	abcb1	abcb1	NOUN
fnp-3528	1573	42	in	in	ADP
fnp-3528	1573	43	mice	mice	NOUN
fnp-3528	1573	44	disrupts	disrupt	VERB
fnp-3528	1573	45	genomic	genomic	ADJ
fnp-3528	1573	46	locus	locus	NOUN
fnp-3528	1573	47	lessons	lesson	NOUN
fnp-3528	1573	48	from	from	ADP
fnp-3528	1573	49	three	three	NUM
fnp-3528	1573	50	unsuccessful	unsuccessful	ADJ
fnp-3528	1573	51	approaches	approach	NOUN
fnp-3528	1573	52	.	.	PUNCT
fnp-3528	1574	1	eur	eur	PROPN
fnp-3528	1574	2	j	j	PROPN
fnp-3528	1574	3	microbiol	microbiol	PROPN
fnp-3528	1574	4	immunol	immunol	NOUN
fnp-3528	1574	5	(	(	PUNCT
fnp-3528	1574	6	bp	bp	PROPN
fnp-3528	1574	7	)	)	PUNCT
fnp-3528	1574	8	2018	2018	NUM
fnp-3528	1574	9	,	,	PUNCT
fnp-3528	1574	10	8	8	NUM
fnp-3528	1574	11	,	,	PUNCT
fnp-3528	1574	12	78	78	NUM
fnp-3528	1574	13	-	-	SYM
fnp-3528	1574	14	86	86	NUM
fnp-3528	1574	15	.	.	PUNCT
fnp-3528	1575	1	willmann	willmann	PROPN
fnp-3528	1575	2	,	,	PUNCT
fnp-3528	1575	3	j.	j.	PROPN
fnp-3528	1575	4	k.	k.	PROPN
fnp-3528	1575	5	;	;	PUNCT
fnp-3528	1575	6	van	van	PROPN
fnp-3528	1575	7	bruggen	bruggen	NOUN
fnp-3528	1575	8	,	,	PUNCT
fnp-3528	1575	9	n.	n.	NOUN
fnp-3528	1575	10	;	;	PUNCT
fnp-3528	1575	11	dinkelborg	dinkelborg	PROPN
fnp-3528	1575	12	,	,	PUNCT
fnp-3528	1575	13	l.	l.	PROPN
fnp-3528	1575	14	m.	m.	PROPN
fnp-3528	1575	15	;	;	PUNCT
fnp-3528	1575	16	gambhir	gambhir	PROPN
fnp-3528	1575	17	,	,	PUNCT
fnp-3528	1575	18	s.	s.	PROPN
fnp-3528	1575	19	s.	s.	PROPN
fnp-3528	1575	20	molecular	molecular	ADJ
fnp-3528	1575	21	imaging	imaging	NOUN
fnp-3528	1575	22	in	in	ADP
fnp-3528	1575	23	drug	drug	NOUN
fnp-3528	1575	24	development	development	NOUN
fnp-3528	1575	25	.	.	PUNCT
fnp-3528	1576	1	nat	nat	PROPN
fnp-3528	1576	2	rev	rev	VERB
fnp-3528	1576	3	drug	drug	PROPN
fnp-3528	1576	4	discov	discov	PROPN
fnp-3528	1576	5	2008	2008	NUM
fnp-3528	1576	6	,	,	PUNCT
fnp-3528	1576	7	7	7	NUM
fnp-3528	1576	8	,	,	PUNCT
fnp-3528	1576	9	591	591	NUM
fnp-3528	1576	10	-	-	SYM
fnp-3528	1576	11	607	607	NUM
fnp-3528	1576	12	.	.	PUNCT
fnp-3528	1577	1	mairinger	mairinger	NOUN
fnp-3528	1577	2	,	,	PUNCT
fnp-3528	1577	3	s.	s.	PROPN
fnp-3528	1577	4	;	;	PUNCT
fnp-3528	1577	5	erker	erker	PROPN
fnp-3528	1577	6	,	,	PUNCT
fnp-3528	1577	7	t.	t.	PROPN
fnp-3528	1577	8	;	;	PUNCT
fnp-3528	1577	9	muller	muller	NOUN
fnp-3528	1577	10	,	,	PUNCT
fnp-3528	1577	11	m.	m.	NOUN
fnp-3528	1577	12	;	;	PUNCT
fnp-3528	1577	13	langer	langer	NOUN
fnp-3528	1577	14	,	,	PUNCT
fnp-3528	1577	15	o.	o.	PROPN
fnp-3528	1577	16	pet	pet	ADJ
fnp-3528	1577	17	and	and	CCONJ
fnp-3528	1577	18	spect	spect	ADJ
fnp-3528	1577	19	radiotracers	radiotracer	NOUN
fnp-3528	1577	20	to	to	PART
fnp-3528	1577	21	assess	assess	VERB
fnp-3528	1577	22	function	function	NOUN
fnp-3528	1577	23	and	and	CCONJ
fnp-3528	1577	24	expression	expression	NOUN
fnp-3528	1577	25	of	of	ADP
fnp-3528	1577	26	abc	abc	PROPN
fnp-3528	1577	27	transporters	transporter	NOUN
fnp-3528	1577	28	in	in	ADP
fnp-3528	1577	29	vivo	vivo	NOUN
fnp-3528	1577	30	.	.	PUNCT
fnp-3528	1578	1	curr	curr	PROPN
fnp-3528	1578	2	drug	drug	PROPN
fnp-3528	1578	3	metab	metab	PROPN
fnp-3528	1578	4	2011	2011	NUM
fnp-3528	1578	5	,	,	PUNCT
fnp-3528	1578	6	12	12	NUM
fnp-3528	1578	7	,	,	PUNCT
fnp-3528	1578	8	774	774	NUM
fnp-3528	1578	9	-	-	SYM
fnp-3528	1578	10	92	92	NUM
fnp-3528	1578	11	.	.	PUNCT
fnp-3528	1579	1	zoufal	zoufal	NOUN
fnp-3528	1579	2	,	,	PUNCT
fnp-3528	1579	3	v.	v.	ADP
fnp-3528	1579	4	;	;	PUNCT
fnp-3528	1579	5	mairinger	mairinger	NOUN
fnp-3528	1579	6	,	,	PUNCT
fnp-3528	1579	7	s.	s.	PROPN
fnp-3528	1579	8	;	;	PUNCT
fnp-3528	1579	9	krohn	krohn	PROPN
fnp-3528	1579	10	,	,	PUNCT
fnp-3528	1579	11	m.	m.	NOUN
fnp-3528	1579	12	;	;	PUNCT
fnp-3528	1579	13	wanek	wanek	ADJ
fnp-3528	1579	14	,	,	PUNCT
fnp-3528	1579	15	t.	t.	PROPN
fnp-3528	1579	16	;	;	PUNCT
fnp-3528	1579	17	filip	filip	PROPN
fnp-3528	1579	18	,	,	PUNCT
fnp-3528	1579	19	t.	t.	PROPN
fnp-3528	1579	20	;	;	PUNCT
fnp-3528	1579	21	sauberer	sauberer	X
fnp-3528	1579	22	,	,	PUNCT
fnp-3528	1579	23	m.	m.	NOUN
fnp-3528	1579	24	;	;	PUNCT
fnp-3528	1579	25	stanek	stanek	PROPN
fnp-3528	1579	26	,	,	PUNCT
fnp-3528	1579	27	j.	j.	PROPN
fnp-3528	1579	28	;	;	PUNCT
fnp-3528	1579	29	traxl	traxl	NOUN
fnp-3528	1579	30	,	,	PUNCT
fnp-3528	1579	31	a.	a.	NOUN
fnp-3528	1579	32	;	;	PUNCT
fnp-3528	1579	33	schuetz	schuetz	VERB
fnp-3528	1579	34	,	,	PUNCT
fnp-3528	1579	35	j.	j.	PROPN
fnp-3528	1579	36	d.	d.	PROPN
fnp-3528	1579	37	;	;	PUNCT
fnp-3528	1579	38	kuntner	kuntner	PROPN
fnp-3528	1579	39	,	,	PUNCT
fnp-3528	1579	40	c.	c.	NOUN
fnp-3528	1579	41	;	;	PUNCT
fnp-3528	1579	42	pahnke	pahnke	PROPN
fnp-3528	1579	43	,	,	PUNCT
fnp-3528	1579	44	j.	j.	PROPN
fnp-3528	1579	45	;	;	PUNCT
fnp-3528	1579	46	langer	langer	NOUN
fnp-3528	1579	47	,	,	PUNCT
fnp-3528	1579	48	o.	o.	ADJ
fnp-3528	1579	49	influence	influence	NOUN
fnp-3528	1579	50	of	of	ADP
fnp-3528	1579	51	multidrug	multidrug	NOUN
fnp-3528	1579	52	resistance	resistance	NOUN
fnp-3528	1579	53	-	-	PUNCT
fnp-3528	1579	54	associated	associate	VERB
fnp-3528	1579	55	proteins	protein	NOUN
fnp-3528	1579	56	on	on	ADP
fnp-3528	1579	57	the	the	DET
fnp-3528	1579	58	excretion	excretion	NOUN
fnp-3528	1579	59	of	of	ADP
fnp-3528	1579	60	the	the	DET
fnp-3528	1579	61	abcc1	abcc1	PROPN
fnp-3528	1579	62	imaging	imaging	PROPN
fnp-3528	1579	63	probe	probe	VERB
fnp-3528	1579	64	6	6	NUM
fnp-3528	1579	65	-	-	PUNCT
fnp-3528	1579	66	bromo-7-[(11)c]methylpurine	bromo-7-[(11)c]methylpurine	NOUN
fnp-3528	1579	67	in	in	ADP
fnp-3528	1579	68	mice	mouse	NOUN
fnp-3528	1579	69	.	.	PUNCT
fnp-3528	1580	1	mol	mol	ADP
fnp-3528	1580	2	imaging	image	VERB
fnp-3528	1580	3	biol	biol	PROPN
fnp-3528	1580	4	2019	2019	NUM
fnp-3528	1580	5	,	,	PUNCT
fnp-3528	1580	6	21	21	NUM
fnp-3528	1580	7	,	,	PUNCT
fnp-3528	1580	8	306	306	NUM
fnp-3528	1580	9	-	-	SYM
fnp-3528	1580	10	16	16	NUM
fnp-3528	1580	11	.	.	PUNCT
fnp-3528	1581	1	wanek	wanek	ADJ
fnp-3528	1581	2	,	,	PUNCT
fnp-3528	1581	3	t.	t.	PROPN
fnp-3528	1581	4	;	;	PUNCT
fnp-3528	1581	5	zoufal	zoufal	NOUN
fnp-3528	1581	6	,	,	PUNCT
fnp-3528	1581	7	v.	v.	ADV
fnp-3528	1581	8	;	;	PUNCT
fnp-3528	1581	9	brackhan	brackhan	PROPN
fnp-3528	1581	10	,	,	PUNCT
fnp-3528	1581	11	m.	m.	NOUN
fnp-3528	1581	12	;	;	PUNCT
fnp-3528	1581	13	krohn	krohn	PROPN
fnp-3528	1581	14	,	,	PUNCT
fnp-3528	1581	15	m.	m.	NOUN
fnp-3528	1581	16	;	;	PUNCT
fnp-3528	1581	17	mairinger	mairinger	NOUN
fnp-3528	1581	18	,	,	PUNCT
fnp-3528	1581	19	s.	s.	PROPN
fnp-3528	1581	20	;	;	PUNCT
fnp-3528	1581	21	filip	filip	PROPN
fnp-3528	1581	22	,	,	PUNCT
fnp-3528	1581	23	t.	t.	PROPN
fnp-3528	1581	24	;	;	PUNCT
fnp-3528	1581	25	sauberer	sauberer	X
fnp-3528	1581	26	,	,	PUNCT
fnp-3528	1581	27	m.	m.	NOUN
fnp-3528	1581	28	;	;	PUNCT
fnp-3528	1581	29	stanek	stanek	PROPN
fnp-3528	1581	30	,	,	PUNCT
fnp-3528	1581	31	j.	j.	PROPN
fnp-3528	1581	32	;	;	PUNCT
fnp-3528	1581	33	pekar	pekar	PROPN
fnp-3528	1581	34	,	,	PUNCT
fnp-3528	1581	35	t.	t.	PROPN
fnp-3528	1581	36	;	;	PUNCT
fnp-3528	1581	37	pahnke	pahnke	PROPN
fnp-3528	1581	38	,	,	PUNCT
fnp-3528	1581	39	j.	j.	PROPN
fnp-3528	1581	40	;	;	PUNCT
fnp-3528	1581	41	langer	langer	NOUN
fnp-3528	1581	42	,	,	PUNCT
fnp-3528	1581	43	o.	o.	NOUN
fnp-3528	1581	44	brain	brain	NOUN
fnp-3528	1581	45	distribution	distribution	NOUN
fnp-3528	1581	46	of	of	ADP
fnp-3528	1581	47	dual	dual	ADJ
fnp-3528	1581	48	abcb1	abcb1	NOUN
fnp-3528	1581	49	/	/	SYM
fnp-3528	1581	50	abgc2	abgc2	NOUN
fnp-3528	1581	51	substrates	substrate	NOUN
fnp-3528	1581	52	is	be	AUX
fnp-3528	1581	53	unaltered	unaltere	VERB
fnp-3528	1581	54	in	in	ADP
fnp-3528	1581	55	a	a	DET
fnp-3528	1581	56	beta	beta	NOUN
fnp-3528	1581	57	-	-	PUNCT
fnp-3528	1581	58	amyloidosis	amyloidosis	NOUN
fnp-3528	1581	59	mouse	mouse	NOUN
fnp-3528	1581	60	model	model	NOUN
fnp-3528	1581	61	.	.	PUNCT
fnp-3528	1582	1	int	int	PROPN
fnp-3528	1582	2	j	j	PROPN
fnp-3528	1582	3	mol	mol	ADP
fnp-3528	1582	4	sci	sci	PROPN
fnp-3528	1582	5	2020	2020	NUM
fnp-3528	1582	6	,	,	PUNCT
fnp-3528	1582	7	21	21	NUM
fnp-3528	1582	8	,	,	PUNCT
fnp-3528	1582	9	8245	8245	NUM
fnp-3528	1582	10	.	.	PUNCT
fnp-3528	1583	1	zoufal	zoufal	NOUN
fnp-3528	1583	2	,	,	PUNCT
fnp-3528	1583	3	v.	v.	ADV
fnp-3528	1583	4	;	;	PUNCT
fnp-3528	1583	5	wanek	wanek	ADJ
fnp-3528	1583	6	,	,	PUNCT
fnp-3528	1583	7	t.	t.	PROPN
fnp-3528	1583	8	;	;	PUNCT
fnp-3528	1583	9	krohn	krohn	PROPN
fnp-3528	1583	10	,	,	PUNCT
fnp-3528	1583	11	m.	m.	NOUN
fnp-3528	1583	12	;	;	PUNCT
fnp-3528	1583	13	mairinger	mairinger	NOUN
fnp-3528	1583	14	,	,	PUNCT
fnp-3528	1583	15	s.	s.	PROPN
fnp-3528	1583	16	;	;	PUNCT
fnp-3528	1583	17	filip	filip	PROPN
fnp-3528	1583	18	,	,	PUNCT
fnp-3528	1583	19	t.	t.	PROPN
fnp-3528	1583	20	;	;	PUNCT
fnp-3528	1583	21	sauberer	sauberer	X
fnp-3528	1583	22	,	,	PUNCT
fnp-3528	1583	23	m.	m.	NOUN
fnp-3528	1583	24	;	;	PUNCT
fnp-3528	1583	25	stanek	stanek	PROPN
fnp-3528	1583	26	,	,	PUNCT
fnp-3528	1583	27	j.	j.	PROPN
fnp-3528	1583	28	;	;	PUNCT
fnp-3528	1583	29	pekar	pekar	PROPN
fnp-3528	1583	30	,	,	PUNCT
fnp-3528	1583	31	t.	t.	PROPN
fnp-3528	1583	32	;	;	PUNCT
fnp-3528	1583	33	bauer	bauer	PROPN
fnp-3528	1583	34	,	,	PUNCT
fnp-3528	1583	35	m.	m.	NOUN
fnp-3528	1583	36	;	;	PUNCT
fnp-3528	1583	37	pahnke	pahnke	PROPN
fnp-3528	1583	38	,	,	PUNCT
fnp-3528	1583	39	j.	j.	PROPN
fnp-3528	1583	40	;	;	PUNCT
fnp-3528	1583	41	langer	langer	NOUN
fnp-3528	1583	42	,	,	PUNCT
fnp-3528	1583	43	o.	o.	NOUN
fnp-3528	1583	44	age	age	NOUN
fnp-3528	1583	45	dependency	dependency	NOUN
fnp-3528	1583	46	of	of	ADP
fnp-3528	1583	47	cerebral	cerebral	ADJ
fnp-3528	1583	48	p	p	NOUN
fnp-3528	1583	49	-	-	PUNCT
fnp-3528	1583	50	glycoprotein	glycoprotein	NOUN
fnp-3528	1583	51	function	function	NOUN
fnp-3528	1583	52	in	in	ADP
fnp-3528	1583	53	wild	wild	ADJ
fnp-3528	1583	54	-	-	PUNCT
fnp-3528	1583	55	type	type	NOUN
fnp-3528	1583	56	and	and	CCONJ
fnp-3528	1583	57	appps1	appps1	NOUN
fnp-3528	1583	58	mice	mouse	NOUN
fnp-3528	1583	59	measured	measure	VERB
fnp-3528	1583	60	with	with	ADP
fnp-3528	1583	61	pet	pet	NOUN
fnp-3528	1583	62	.	.	PUNCT
fnp-3528	1584	1	j	j	PROPN
fnp-3528	1584	2	cereb	cereb	PROPN
fnp-3528	1584	3	blood	blood	NOUN
fnp-3528	1584	4	flow	flow	NOUN
fnp-3528	1584	5	metab	metab	NOUN
fnp-3528	1584	6	2018	2018	NUM
fnp-3528	1584	7	,	,	PUNCT
fnp-3528	1584	8	40	40	NUM
fnp-3528	1584	9	,	,	PUNCT
fnp-3528	1584	10	150	150	NUM
fnp-3528	1584	11	-	-	SYM
fnp-3528	1584	12	62	62	NUM
fnp-3528	1584	13	.	.	PUNCT
fnp-3528	1585	1	campbell	campbell	PROPN
fnp-3528	1585	2	,	,	PUNCT
fnp-3528	1585	3	b.	b.	PROPN
fnp-3528	1585	4	r.	r.	PROPN
fnp-3528	1585	5	;	;	PUNCT
fnp-3528	1585	6	gonzalez	gonzalez	PROPN
fnp-3528	1585	7	trotter	trotter	PROPN
fnp-3528	1585	8	,	,	PUNCT
fnp-3528	1585	9	d.	d.	PROPN
fnp-3528	1585	10	;	;	PUNCT
fnp-3528	1585	11	hines	hines	PROPN
fnp-3528	1585	12	,	,	PUNCT
fnp-3528	1585	13	c.	c.	PROPN
fnp-3528	1585	14	d.	d.	PROPN
fnp-3528	1585	15	;	;	PUNCT
fnp-3528	1585	16	li	li	PROPN
fnp-3528	1585	17	,	,	PUNCT
fnp-3528	1585	18	w.	w.	PROPN
fnp-3528	1585	19	;	;	PUNCT
fnp-3528	1585	20	patel	patel	PROPN
fnp-3528	1585	21	,	,	PUNCT
fnp-3528	1585	22	m.	m.	NOUN
fnp-3528	1585	23	;	;	PUNCT
fnp-3528	1585	24	zhang	zhang	PROPN
fnp-3528	1585	25	,	,	PUNCT
fnp-3528	1585	26	w.	w.	PROPN
fnp-3528	1585	27	;	;	PUNCT
fnp-3528	1585	28	evelhoch	evelhoch	PROPN
fnp-3528	1585	29	,	,	PUNCT
fnp-3528	1585	30	j.	j.	PROPN
fnp-3528	1585	31	l.	l.	PROPN
fnp-3528	1585	32	in	in	ADP
fnp-3528	1585	33	vivo	vivo	ADJ
fnp-3528	1585	34	imaging	imaging	NOUN
fnp-3528	1585	35	in	in	ADP
fnp-3528	1585	36	pharmaceutical	pharmaceutical	ADJ
fnp-3528	1585	37	development	development	NOUN
fnp-3528	1585	38	and	and	CCONJ
fnp-3528	1585	39	its	its	PRON
fnp-3528	1585	40	impact	impact	NOUN
fnp-3528	1585	41	on	on	ADP
fnp-3528	1585	42	the	the	DET
fnp-3528	1585	43	3rs	3rs	NOUN
fnp-3528	1585	44	.	.	PUNCT
fnp-3528	1586	1	ilar	ilar	PROPN
fnp-3528	1586	2	j	j	PROPN
fnp-3528	1586	3	2016	2016	NUM
fnp-3528	1586	4	,	,	PUNCT
fnp-3528	1586	5	57	57	NUM
fnp-3528	1586	6	,	,	PUNCT
fnp-3528	1586	7	212	212	NUM
fnp-3528	1586	8	-	-	SYM
fnp-3528	1586	9	20	20	NUM
fnp-3528	1586	10	.	.	PUNCT
fnp-3528	1587	1	bieczynski	bieczynski	NOUN
fnp-3528	1587	2	,	,	PUNCT
fnp-3528	1587	3	f.	f.	PROPN
fnp-3528	1587	4	;	;	PUNCT
fnp-3528	1587	5	burkhardt	burkhardt	NOUN
fnp-3528	1587	6	-	-	PUNCT
fnp-3528	1587	7	medicke	medicke	NOUN
fnp-3528	1587	8	,	,	PUNCT
fnp-3528	1587	9	k.	k.	PROPN
fnp-3528	1587	10	;	;	PUNCT
fnp-3528	1587	11	luquet	luquet	PROPN
fnp-3528	1587	12	,	,	PUNCT
fnp-3528	1587	13	c.	c.	NOUN
fnp-3528	1587	14	m.	m.	NOUN
fnp-3528	1587	15	;	;	PUNCT
fnp-3528	1587	16	scholz	scholz	NOUN
fnp-3528	1587	17	,	,	PUNCT
fnp-3528	1587	18	s.	s.	PROPN
fnp-3528	1587	19	;	;	PUNCT
fnp-3528	1587	20	luckenbach	luckenbach	PROPN
fnp-3528	1587	21	,	,	PUNCT
fnp-3528	1587	22	t.	t.	NOUN
fnp-3528	1587	23	chemical	chemical	NOUN
fnp-3528	1587	24	effects	effect	NOUN
fnp-3528	1587	25	on	on	ADP
fnp-3528	1587	26	dye	dye	NOUN
fnp-3528	1587	27	efflux	efflux	NOUN
fnp-3528	1587	28	activity	activity	NOUN
fnp-3528	1587	29	in	in	ADP
fnp-3528	1587	30	live	live	ADJ
fnp-3528	1587	31	zebrafish	zebrafish	ADJ
fnp-3528	1587	32	embryos	embryo	NOUN
fnp-3528	1587	33	and	and	CCONJ
fnp-3528	1587	34	on	on	ADP
fnp-3528	1587	35	zebrafish	zebrafish	ADJ
fnp-3528	1587	36	abcb4	abcb4	PROPN
fnp-3528	1587	37	atpase	atpase	NOUN
fnp-3528	1587	38	activity	activity	NOUN
fnp-3528	1587	39	.	.	PUNCT
fnp-3528	1588	1	febs	febs	PROPN
fnp-3528	1588	2	lett	lett	PROPN
fnp-3528	1588	3	2021	2021	NUM
fnp-3528	1588	4	,	,	PUNCT
fnp-3528	1588	5	595	595	NUM
fnp-3528	1588	6	,	,	PUNCT
fnp-3528	1588	7	828	828	NUM
fnp-3528	1588	8	-	-	SYM
fnp-3528	1588	9	43	43	NUM
fnp-3528	1588	10	.	.	PUNCT
fnp-3528	1589	1	pedersen	pedersen	PROPN
fnp-3528	1589	2	,	,	PUNCT
fnp-3528	1589	3	j.	j.	PROPN
fnp-3528	1589	4	m.	m.	PROPN
fnp-3528	1589	5	;	;	PUNCT
fnp-3528	1589	6	matsson	matsson	PROPN
fnp-3528	1589	7	,	,	PUNCT
fnp-3528	1589	8	p.	p.	PROPN
fnp-3528	1589	9	;	;	PUNCT
fnp-3528	1589	10	bergstrom	bergstrom	PROPN
fnp-3528	1589	11	,	,	PUNCT
fnp-3528	1589	12	c.	c.	PROPN
fnp-3528	1589	13	a.	a.	PROPN
fnp-3528	1589	14	;	;	PUNCT
fnp-3528	1589	15	hoogstraate	hoogstraate	VERB
fnp-3528	1589	16	,	,	PUNCT
fnp-3528	1589	17	j.	j.	PROPN
fnp-3528	1589	18	;	;	PUNCT
fnp-3528	1589	19	noren	noren	PROPN
fnp-3528	1589	20	,	,	PUNCT
fnp-3528	1589	21	a.	a.	PROPN
fnp-3528	1589	22	;	;	PUNCT
fnp-3528	1589	23	lecluyse	lecluyse	PROPN
fnp-3528	1589	24	,	,	PUNCT
fnp-3528	1589	25	e.	e.	PROPN
fnp-3528	1589	26	l.	l.	PROPN
fnp-3528	1589	27	;	;	PUNCT
fnp-3528	1589	28	artursson	artursson	PROPN
fnp-3528	1589	29	,	,	PUNCT
fnp-3528	1590	1	p.	p.	NOUN
fnp-3528	1590	2	early	early	ADJ
fnp-3528	1590	3	identification	identification	NOUN
fnp-3528	1590	4	of	of	ADP
fnp-3528	1590	5	clinically	clinically	ADV
fnp-3528	1590	6	relevant	relevant	ADJ
fnp-3528	1590	7	drug	drug	NOUN
fnp-3528	1590	8	interactions	interaction	NOUN
fnp-3528	1590	9	with	with	ADP
fnp-3528	1590	10	the	the	DET
fnp-3528	1590	11	human	human	ADJ
fnp-3528	1590	12	bile	bile	NOUN
fnp-3528	1590	13	salt	salt	NOUN
fnp-3528	1590	14	export	export	NOUN
fnp-3528	1590	15	pump	pump	NOUN
fnp-3528	1590	16	(	(	PUNCT
fnp-3528	1590	17	bsep	bsep	NOUN
fnp-3528	1590	18	/	/	SYM
fnp-3528	1590	19	abcb11	abcb11	NOUN
fnp-3528	1590	20	)	)	PUNCT
fnp-3528	1590	21	.	.	PUNCT
fnp-3528	1591	1	toxicol	toxicol	PROPN
fnp-3528	1591	2	sci	sci	PROPN
fnp-3528	1591	3	2013	2013	NUM
fnp-3528	1591	4	,	,	PUNCT
fnp-3528	1591	5	136	136	NUM
fnp-3528	1591	6	,	,	PUNCT
fnp-3528	1591	7	328	328	NUM
fnp-3528	1591	8	-	-	SYM
fnp-3528	1591	9	43	43	NUM
fnp-3528	1591	10	.	.	PUNCT
fnp-3528	1592	1	matsson	matsson	NOUN
fnp-3528	1592	2	,	,	PUNCT
fnp-3528	1592	3	p.	p.	NOUN
fnp-3528	1592	4	;	;	PUNCT
fnp-3528	1592	5	pedersen	pedersen	PROPN
fnp-3528	1592	6	,	,	PUNCT
fnp-3528	1592	7	j.	j.	PROPN
fnp-3528	1592	8	m.	m.	PROPN
fnp-3528	1592	9	;	;	PUNCT
fnp-3528	1592	10	norinder	norinder	PROPN
fnp-3528	1592	11	,	,	PUNCT
fnp-3528	1592	12	u.	u.	PROPN
fnp-3528	1592	13	;	;	PUNCT
fnp-3528	1592	14	bergstrom	bergstrom	PROPN
fnp-3528	1592	15	,	,	PUNCT
fnp-3528	1592	16	c.	c.	PROPN
fnp-3528	1592	17	a.	a.	PROPN
fnp-3528	1592	18	;	;	PUNCT
fnp-3528	1592	19	artursson	artursson	NOUN
fnp-3528	1592	20	,	,	PUNCT
fnp-3528	1592	21	p.	p.	NOUN
fnp-3528	1592	22	identification	identification	NOUN
fnp-3528	1592	23	of	of	ADP
fnp-3528	1592	24	novel	novel	ADJ
fnp-3528	1592	25	specific	specific	ADJ
fnp-3528	1592	26	and	and	CCONJ
fnp-3528	1592	27	general	general	ADJ
fnp-3528	1592	28	inhibitors	inhibitor	NOUN
fnp-3528	1592	29	of	of	ADP
fnp-3528	1592	30	the	the	DET
fnp-3528	1592	31	three	three	NUM
fnp-3528	1592	32	major	major	ADJ
fnp-3528	1592	33	human	human	ADJ
fnp-3528	1592	34	atp	atp	NOUN
fnp-3528	1592	35	-	-	PUNCT
fnp-3528	1592	36	binding	bind	VERB
fnp-3528	1592	37	cassette	cassette	NOUN
fnp-3528	1592	38	transporters	transporter	NOUN
fnp-3528	1592	39	p	p	NOUN
fnp-3528	1592	40	-	-	PUNCT
fnp-3528	1592	41	gp	gp	NOUN
fnp-3528	1592	42	,	,	PUNCT
fnp-3528	1592	43	bcrp	bcrp	VERB
fnp-3528	1592	44	and	and	CCONJ
fnp-3528	1592	45	mrp2	mrp2	VERB
fnp-3528	1592	46	among	among	ADP
fnp-3528	1592	47	registered	registered	ADJ
fnp-3528	1592	48	drugs	drug	NOUN
fnp-3528	1592	49	.	.	PUNCT
fnp-3528	1593	1	pharm	pharm	NOUN
fnp-3528	1593	2	res	re	NOUN
fnp-3528	1593	3	2009	2009	NUM
fnp-3528	1593	4	,	,	PUNCT
fnp-3528	1593	5	26	26	NUM
fnp-3528	1593	6	,	,	PUNCT
fnp-3528	1593	7	1816	1816	NUM
fnp-3528	1593	8	-	-	SYM
fnp-3528	1593	9	31	31	NUM
fnp-3528	1593	10	.	.	PUNCT
fnp-3528	1594	1	cserepes	cserepe	NOUN
fnp-3528	1594	2	,	,	PUNCT
fnp-3528	1594	3	j.	j.	PROPN
fnp-3528	1594	4	;	;	PUNCT
fnp-3528	1594	5	szentpetery	szentpetery	NOUN
fnp-3528	1594	6	,	,	PUNCT
fnp-3528	1594	7	z.	z.	PROPN
fnp-3528	1594	8	;	;	PUNCT
fnp-3528	1594	9	seres	sere	NOUN
fnp-3528	1594	10	,	,	PUNCT
fnp-3528	1594	11	l.	l.	PROPN
fnp-3528	1594	12	;	;	PUNCT
fnp-3528	1594	13	ozvegy	ozvegy	NOUN
fnp-3528	1594	14	-	-	PUNCT
fnp-3528	1594	15	laczka	laczka	PROPN
fnp-3528	1594	16	,	,	PUNCT
fnp-3528	1594	17	c.	c.	NOUN
fnp-3528	1594	18	;	;	PUNCT
fnp-3528	1594	19	langmann	langmann	PROPN
fnp-3528	1594	20	,	,	PUNCT
fnp-3528	1594	21	t.	t.	PROPN
fnp-3528	1594	22	;	;	PUNCT
fnp-3528	1594	23	schmitz	schmitz	PROPN
fnp-3528	1594	24	,	,	PUNCT
fnp-3528	1594	25	g.	g.	PROPN
fnp-3528	1594	26	;	;	PUNCT
fnp-3528	1594	27	glavinas	glavinas	PROPN
fnp-3528	1594	28	,	,	PUNCT
fnp-3528	1594	29	h.	h.	PROPN
fnp-3528	1594	30	;	;	PUNCT
fnp-3528	1594	31	klein	klein	PROPN
fnp-3528	1594	32	,	,	PUNCT
fnp-3528	1594	33	i.	i.	PROPN
fnp-3528	1594	34	;	;	PUNCT
fnp-3528	1594	35	homolya	homolya	PROPN
fnp-3528	1594	36	,	,	PUNCT
fnp-3528	1594	37	l.	l.	PROPN
fnp-3528	1594	38	;	;	PUNCT
fnp-3528	1594	39	varadi	varadi	NOUN
fnp-3528	1594	40	,	,	PUNCT
fnp-3528	1594	41	a.	a.	NOUN
fnp-3528	1594	42	;	;	PUNCT
fnp-3528	1594	43	sarkadi	sarkadi	PROPN
fnp-3528	1594	44	,	,	PUNCT
fnp-3528	1594	45	b.	b.	PROPN
fnp-3528	1594	46	;	;	PUNCT
fnp-3528	1594	47	elkind	elkind	ADJ
fnp-3528	1594	48	,	,	PUNCT
fnp-3528	1594	49	n.	n.	PROPN
fnp-3528	1594	50	b.	b.	PROPN
fnp-3528	1594	51	functional	functional	ADJ
fnp-3528	1594	52	expression	expression	NOUN
fnp-3528	1594	53	and	and	CCONJ
fnp-3528	1594	54	characterization	characterization	NOUN
fnp-3528	1594	55	of	of	ADP
fnp-3528	1594	56	the	the	DET
fnp-3528	1594	57	human	human	ADJ
fnp-3528	1594	58	abcg1	abcg1	PROPN
fnp-3528	1594	59	and	and	CCONJ
fnp-3528	1594	60	abcg4	abcg4	PROPN
fnp-3528	1594	61	proteins	protein	NOUN
fnp-3528	1594	62	:	:	PUNCT
fnp-3528	1594	63	indications	indication	NOUN
fnp-3528	1594	64	for	for	ADP
fnp-3528	1594	65	heterodimerization	heterodimerization	NOUN
fnp-3528	1594	66	.	.	PUNCT
fnp-3528	1595	1	biochem	biochem	PROPN
fnp-3528	1595	2	biophys	biophys	PROPN
fnp-3528	1595	3	res	res	PROPN
fnp-3528	1595	4	commun	commun	PROPN
fnp-3528	1595	5	2004	2004	NUM
fnp-3528	1595	6	,	,	PUNCT
fnp-3528	1595	7	320	320	NUM
fnp-3528	1595	8	,	,	PUNCT
fnp-3528	1595	9	860	860	NUM
fnp-3528	1595	10	-	-	SYM
fnp-3528	1595	11	7	7	NUM
fnp-3528	1595	12	.	.	PUNCT
fnp-3528	1595	13	ivnitski	ivnitski	PROPN
fnp-3528	1595	14	-	-	PUNCT
fnp-3528	1595	15	steele	steele	PROPN
fnp-3528	1595	16	,	,	PUNCT
fnp-3528	1595	17	i.	i.	PROPN
fnp-3528	1595	18	;	;	PUNCT
fnp-3528	1595	19	larson	larson	PROPN
fnp-3528	1595	20	,	,	PUNCT
fnp-3528	1595	21	r.	r.	PROPN
fnp-3528	1595	22	s.	s.	PROPN
fnp-3528	1595	23	;	;	PUNCT
fnp-3528	1595	24	lovato	lovato	PROPN
fnp-3528	1595	25	,	,	PUNCT
fnp-3528	1595	26	d.	d.	PROPN
fnp-3528	1595	27	m.	m.	PROPN
fnp-3528	1595	28	;	;	PUNCT
fnp-3528	1595	29	khawaja	khawaja	PROPN
fnp-3528	1595	30	,	,	PUNCT
fnp-3528	1595	31	h.	h.	PROPN
fnp-3528	1595	32	m.	m.	NOUN
fnp-3528	1595	33	;	;	PUNCT
fnp-3528	1595	34	winter	winter	NOUN
fnp-3528	1595	35	,	,	PUNCT
fnp-3528	1595	36	s.	s.	PROPN
fnp-3528	1595	37	s.	s.	PROPN
fnp-3528	1595	38	;	;	PUNCT
fnp-3528	1595	39	oprea	oprea	PROPN
fnp-3528	1595	40	,	,	PUNCT
fnp-3528	1595	41	t.	t.	PROPN
fnp-3528	1595	42	i.	i.	PROPN
fnp-3528	1595	43	;	;	PUNCT
fnp-3528	1595	44	sklar	sklar	PROPN
fnp-3528	1595	45	,	,	PUNCT
fnp-3528	1595	46	l.	l.	PROPN
fnp-3528	1595	47	a.	a.	PROPN
fnp-3528	1595	48	;	;	PUNCT
fnp-3528	1595	49	edwards	edwards	PROPN
fnp-3528	1595	50	,	,	PUNCT
fnp-3528	1595	51	b.	b.	PROPN
fnp-3528	1595	52	s.	s.	PROPN
fnp-3528	1595	53	high	high	PROPN
fnp-3528	1595	54	-	-	PUNCT
fnp-3528	1595	55	throughput	throughput	NOUN
fnp-3528	1595	56	flow	flow	NOUN
fnp-3528	1595	57	cytometry	cytometry	NOUN
fnp-3528	1595	58	to	to	PART
fnp-3528	1595	59	detect	detect	VERB
fnp-3528	1595	60	selective	selective	ADJ
fnp-3528	1595	61	inhibitors	inhibitor	NOUN
fnp-3528	1595	62	of	of	ADP
fnp-3528	1595	63	abcb1	abcb1	NOUN
fnp-3528	1595	64	,	,	PUNCT
fnp-3528	1595	65	abcc1	abcc1	PROPN
fnp-3528	1595	66	,	,	PUNCT
fnp-3528	1595	67	and	and	CCONJ
fnp-3528	1595	68	abcg2	abcg2	NOUN
fnp-3528	1595	69	transporters	transporter	NOUN
fnp-3528	1596	1	.	.	PUNCT
fnp-3528	1597	1	assay	assay	PROPN
fnp-3528	1597	2	drug	drug	PROPN
fnp-3528	1597	3	dev	dev	PROPN
fnp-3528	1597	4	technol	technol	PROPN
fnp-3528	1597	5	2008	2008	NUM
fnp-3528	1597	6	,	,	PUNCT
fnp-3528	1597	7	6	6	NUM
fnp-3528	1597	8	,	,	PUNCT
fnp-3528	1597	9	263	263	NUM
fnp-3528	1597	10	-	-	SYM
fnp-3528	1597	11	76	76	NUM
fnp-3528	1597	12	.	.	PUNCT
fnp-3528	1598	1	borst	borst	PROPN
fnp-3528	1598	2	,	,	PUNCT
fnp-3528	1598	3	p.	p.	NOUN
fnp-3528	1598	4	;	;	PUNCT
fnp-3528	1598	5	de	de	X
fnp-3528	1598	6	wolf	wolf	PROPN
fnp-3528	1598	7	,	,	PUNCT
fnp-3528	1598	8	c.	c.	PROPN
fnp-3528	1598	9	;	;	PUNCT
fnp-3528	1598	10	van	van	PROPN
fnp-3528	1598	11	de	de	PROPN
fnp-3528	1598	12	wetering	wetering	PROPN
fnp-3528	1598	13	,	,	PUNCT
fnp-3528	1598	14	k.	k.	PROPN
fnp-3528	1598	15	multidrug	multidrug	VERB
fnp-3528	1598	16	resistance	resistance	NOUN
fnp-3528	1598	17	-	-	PUNCT
fnp-3528	1598	18	associated	associate	VERB
fnp-3528	1598	19	proteins	protein	NOUN
fnp-3528	1598	20	3	3	NUM
fnp-3528	1598	21	,	,	PUNCT
fnp-3528	1598	22	4	4	NUM
fnp-3528	1598	23	,	,	PUNCT
fnp-3528	1598	24	and	and	CCONJ
fnp-3528	1598	25	5	5	NUM
fnp-3528	1598	26	.	.	NOUN
fnp-3528	1598	27	pflugers	pfluger	NOUN
fnp-3528	1598	28	arch	arch	VERB
fnp-3528	1598	29	2007	2007	NUM
fnp-3528	1598	30	,	,	PUNCT
fnp-3528	1598	31	453	453	NUM
fnp-3528	1598	32	,	,	PUNCT
fnp-3528	1598	33	661	661	NUM
fnp-3528	1598	34	-	-	SYM
fnp-3528	1598	35	73	73	NUM
fnp-3528	1598	36	.	.	PUNCT
fnp-3528	1599	1	berghaus	berghaus	PROPN
fnp-3528	1599	2	,	,	PUNCT
fnp-3528	1599	3	a.	a.	NOUN
fnp-3528	1599	4	;	;	PUNCT
fnp-3528	1599	5	jovanovic	jovanovic	PROPN
fnp-3528	1599	6	,	,	PUNCT
fnp-3528	1599	7	s.	s.	PROPN
fnp-3528	1599	8	technique	technique	NOUN
fnp-3528	1599	9	and	and	CCONJ
fnp-3528	1599	10	indications	indication	NOUN
fnp-3528	1599	11	of	of	ADP
fnp-3528	1599	12	extended	extended	ADJ
fnp-3528	1599	13	sublabial	sublabial	ADJ
fnp-3528	1599	14	rhinotomy	rhinotomy	NOUN
fnp-3528	1599	15	(	(	PUNCT
fnp-3528	1599	16	"	"	PUNCT
fnp-3528	1599	17	midfacial	midfacial	NOUN
fnp-3528	1599	18	degloving	degloving	NOUN
fnp-3528	1599	19	"	"	PUNCT
fnp-3528	1599	20	)	)	PUNCT
fnp-3528	1599	21	.	.	PUNCT
fnp-3528	1600	1	rhinol	rhinol	PROPN
fnp-3528	1600	2	1991	1991	NUM
fnp-3528	1600	3	,	,	PUNCT
fnp-3528	1600	4	29	29	NUM
fnp-3528	1600	5	,	,	PUNCT
fnp-3528	1600	6	105	105	NUM
fnp-3528	1600	7	-	-	SYM
fnp-3528	1600	8	10	10	NUM
fnp-3528	1600	9	.	.	PUNCT
fnp-3528	1601	1	lim	lim	PROPN
fnp-3528	1601	2	,	,	PUNCT
fnp-3528	1601	3	j.	j.	PROPN
fnp-3528	1601	4	g.	g.	PROPN
fnp-3528	1601	5	;	;	PUNCT
fnp-3528	1601	6	lee	lee	PROPN
fnp-3528	1601	7	,	,	PUNCT
fnp-3528	1601	8	h.	h.	PROPN
fnp-3528	1601	9	y.	y.	PROPN
fnp-3528	1601	10	;	;	PUNCT
fnp-3528	1601	11	yun	yun	PROPN
fnp-3528	1601	12	,	,	PUNCT
fnp-3528	1601	13	j.	j.	PROPN
fnp-3528	1601	14	e.	e.	PROPN
fnp-3528	1601	15	;	;	PUNCT
fnp-3528	1601	16	kim	kim	PROPN
fnp-3528	1601	17	,	,	PUNCT
fnp-3528	1601	18	s.	s.	PROPN
fnp-3528	1601	19	p.	p.	PROPN
fnp-3528	1601	20	;	;	PUNCT
fnp-3528	1601	21	park	park	PROPN
fnp-3528	1601	22	,	,	PUNCT
fnp-3528	1601	23	j.	j.	PROPN
fnp-3528	1601	24	w.	w.	PROPN
fnp-3528	1601	25	;	;	PUNCT
fnp-3528	1601	26	suh	suh	PROPN
fnp-3528	1601	27	,	,	PUNCT
fnp-3528	1601	28	s.	s.	PROPN
fnp-3528	1601	29	i.	i.	PROPN
fnp-3528	1601	30	;	;	PUNCT
fnp-3528	1601	31	jang	jang	PROPN
fnp-3528	1601	32	,	,	PUNCT
fnp-3528	1601	33	b.	b.	PROPN
fnp-3528	1601	34	c.	c.	PROPN
fnp-3528	1601	35	;	;	PUNCT
fnp-3528	1601	36	cho	cho	PROPN
fnp-3528	1601	37	,	,	PUNCT
fnp-3528	1601	38	c.	c.	PROPN
fnp-3528	1601	39	h.	h.	PROPN
fnp-3528	1601	40	;	;	PUNCT
fnp-3528	1601	41	bae	bae	PROPN
fnp-3528	1601	42	,	,	PUNCT
fnp-3528	1601	43	j.	j.	PROPN
fnp-3528	1601	44	h.	h.	PROPN
fnp-3528	1601	45	;	;	PUNCT
fnp-3528	1601	46	kim	kim	PROPN
fnp-3528	1601	47	,	,	PUNCT
fnp-3528	1601	48	s.	s.	PROPN
fnp-3528	1601	49	s.	s.	PROPN
fnp-3528	1601	50	;	;	PUNCT
fnp-3528	1601	51	han	han	PROPN
fnp-3528	1601	52	,	,	PUNCT
fnp-3528	1601	53	j.	j.	PROPN
fnp-3528	1601	54	;	;	PUNCT
fnp-3528	1601	55	park	park	NOUN
fnp-3528	1601	56	,	,	PUNCT
fnp-3528	1601	57	m.	m.	NOUN
fnp-3528	1601	58	j.	j.	PROPN
fnp-3528	1601	59	;	;	PUNCT
fnp-3528	1601	60	song	song	PROPN
fnp-3528	1601	61	,	,	PUNCT
fnp-3528	1601	62	d.	d.	PROPN
fnp-3528	1601	63	k.	k.	PROPN
fnp-3528	1601	64	taurine	taurine	PROPN
fnp-3528	1601	65	block	block	NOUN
fnp-3528	1601	66	of	of	ADP
fnp-3528	1601	67	cloned	cloned	ADJ
fnp-3528	1601	68	atp	atp	PROPN
fnp-3528	1601	69	-	-	PUNCT
fnp-3528	1601	70	sensitive	sensitive	ADJ
fnp-3528	1601	71	k+	k+	NOUN
fnp-3528	1601	72	channels	channel	NOUN
fnp-3528	1601	73	with	with	ADP
fnp-3528	1601	74	different	different	ADJ
fnp-3528	1601	75	sulfonylurea	sulfonylurea	NOUN
fnp-3528	1601	76	receptor	receptor	NOUN
fnp-3528	1601	77	subunits	subunit	NOUN
fnp-3528	1601	78	expressed	express	VERB
fnp-3528	1601	79	in	in	ADP
fnp-3528	1601	80	xenopus	xenopus	PROPN
fnp-3528	1601	81	laevis	laevis	ADJ
fnp-3528	1601	82	oocytes	oocyte	NOUN
fnp-3528	1601	83	.	.	PUNCT
fnp-3528	1602	1	biochem	biochem	PROPN
fnp-3528	1602	2	pharmacol	pharmacol	PROPN
fnp-3528	1602	3	2004	2004	NUM
fnp-3528	1602	4	,	,	PUNCT
fnp-3528	1602	5	68	68	NUM
fnp-3528	1602	6	,	,	PUNCT
fnp-3528	1602	7	901	901	NUM
fnp-3528	1602	8	-	-	SYM
fnp-3528	1602	9	10	10	NUM
fnp-3528	1602	10	.	.	PUNCT
fnp-3528	1603	1	york	york	PROPN
fnp-3528	1603	2	,	,	PUNCT
fnp-3528	1603	3	n.	n.	PROPN
fnp-3528	1603	4	w.	w.	PROPN
fnp-3528	1603	5	;	;	PUNCT
fnp-3528	1603	6	parker	parker	PROPN
fnp-3528	1603	7	,	,	PUNCT
fnp-3528	1603	8	h.	h.	PROPN
fnp-3528	1603	9	;	;	PUNCT
fnp-3528	1603	10	xie	xie	PROPN
fnp-3528	1603	11	,	,	PUNCT
fnp-3528	1603	12	z.	z.	PROPN
fnp-3528	1603	13	;	;	PUNCT
fnp-3528	1603	14	tyus	tyus	PROPN
fnp-3528	1603	15	,	,	PUNCT
fnp-3528	1603	16	d.	d.	PROPN
fnp-3528	1603	17	;	;	PUNCT
fnp-3528	1603	18	waheed	waheed	PROPN
fnp-3528	1603	19	,	,	PUNCT
fnp-3528	1603	20	m.	m.	NOUN
fnp-3528	1603	21	a.	a.	PROPN
fnp-3528	1603	22	;	;	PUNCT
fnp-3528	1603	23	yan	yan	PROPN
fnp-3528	1603	24	,	,	PUNCT
fnp-3528	1603	25	z.	z.	PROPN
fnp-3528	1603	26	;	;	PUNCT
fnp-3528	1603	27	grange	grange	PROPN
fnp-3528	1603	28	,	,	PUNCT
fnp-3528	1603	29	d.	d.	PROPN
fnp-3528	1603	30	k.	k.	PROPN
fnp-3528	1603	31	;	;	PUNCT
fnp-3528	1603	32	remedi	remedi	PROPN
fnp-3528	1603	33	,	,	PUNCT
fnp-3528	1603	34	m.	m.	NOUN
fnp-3528	1603	35	s.	s.	PROPN
fnp-3528	1603	36	;	;	PUNCT
fnp-3528	1603	37	england	england	PROPN
fnp-3528	1603	38	,	,	PUNCT
fnp-3528	1603	39	s.	s.	PROPN
fnp-3528	1603	40	k.	k.	PROPN
fnp-3528	1603	41	;	;	PUNCT
fnp-3528	1603	42	hu	hu	PROPN
fnp-3528	1603	43	,	,	PUNCT
fnp-3528	1603	44	h.	h.	PROPN
fnp-3528	1603	45	;	;	PUNCT
fnp-3528	1603	46	nichols	nichols	PROPN
fnp-3528	1603	47	,	,	PUNCT
fnp-3528	1604	1	c.	c.	PROPN
fnp-3528	1604	2	g.	g.	PROPN
fnp-3528	1604	3	kir6.1and	kir6.1and	PROPN
fnp-3528	1604	4	sur2	sur2	PROPN
fnp-3528	1604	5	-	-	PUNCT
fnp-3528	1604	6	dependent	dependent	ADJ
fnp-3528	1604	7	katp	katp	NOUN
fnp-3528	1604	8	over	over	ADP
fnp-3528	1604	9	-	-	PUNCT
fnp-3528	1604	10	activity	activity	NOUN
fnp-3528	1604	11	disrupts	disrupt	VERB
fnp-3528	1604	12	intestinal	intestinal	ADJ
fnp-3528	1604	13	motility	motility	NOUN
fnp-3528	1604	14	in	in	ADP
fnp-3528	1604	15	murine	murine	ADJ
fnp-3528	1604	16	models	model	NOUN
fnp-3528	1604	17	of	of	ADP
fnp-3528	1604	18	cantu	cantu	PROPN
fnp-3528	1604	19	syndrome	syndrome	PROPN
fnp-3528	1604	20	.	.	PUNCT
fnp-3528	1605	1	jci	jci	PROPN
fnp-3528	1605	2	insight	insight	PROPN
fnp-3528	1605	3	2020	2020	NUM
fnp-3528	1605	4	,	,	PUNCT
fnp-3528	1605	5	5	5	NUM
fnp-3528	1605	6	,	,	PUNCT
fnp-3528	1605	7	e141443	e141443	NOUN
fnp-3528	1605	8	.	.	PUNCT
fnp-3528	1606	1	beretta	beretta	PROPN
fnp-3528	1606	2	,	,	PUNCT
fnp-3528	1606	3	g.	g.	PROPN
fnp-3528	1606	4	l.	l.	PROPN
fnp-3528	1606	5	;	;	PUNCT
fnp-3528	1606	6	cassinelli	cassinelli	PROPN
fnp-3528	1606	7	,	,	PUNCT
fnp-3528	1606	8	g.	g.	PROPN
fnp-3528	1606	9	;	;	PUNCT
fnp-3528	1606	10	pennati	pennati	NOUN
fnp-3528	1606	11	,	,	PUNCT
fnp-3528	1606	12	m.	m.	NOUN
fnp-3528	1606	13	;	;	PUNCT
fnp-3528	1606	14	zuco	zuco	ADJ
fnp-3528	1606	15	,	,	PUNCT
fnp-3528	1606	16	v.	v.	ADV
fnp-3528	1606	17	;	;	PUNCT
fnp-3528	1606	18	gatti	gatti	PROPN
fnp-3528	1606	19	,	,	PUNCT
fnp-3528	1606	20	l.	l.	PROPN
fnp-3528	1606	21	overcoming	overcome	VERB
fnp-3528	1606	22	abc	abc	PROPN
fnp-3528	1606	23	transporter	transporter	NOUN
fnp-3528	1606	24	-	-	PUNCT
fnp-3528	1606	25	mediated	mediate	VERB
fnp-3528	1606	26	multidrug	multidrug	NOUN
fnp-3528	1606	27	resistance	resistance	NOUN
fnp-3528	1606	28	:	:	PUNCT
fnp-3528	1606	29	the	the	DET
fnp-3528	1606	30	dual	dual	ADJ
fnp-3528	1606	31	role	role	NOUN
fnp-3528	1606	32	of	of	ADP
fnp-3528	1606	33	tyrosine	tyrosine	NOUN
fnp-3528	1606	34	kinase	kinase	PROPN
fnp-3528	1606	35	inhibitors	inhibitor	NOUN
fnp-3528	1606	36	as	as	ADP
fnp-3528	1606	37	multitargeting	multitargete	VERB
fnp-3528	1606	38	agents	agent	NOUN
fnp-3528	1606	39	.	.	PUNCT
fnp-3528	1607	1	eur	eur	PROPN
fnp-3528	1607	2	j	j	PROPN
fnp-3528	1607	3	med	med	PROPN
fnp-3528	1607	4	chem	chem	NOUN
fnp-3528	1607	5	2017	2017	NUM
fnp-3528	1607	6	,	,	PUNCT
fnp-3528	1607	7	142	142	NUM
fnp-3528	1607	8	,	,	PUNCT
fnp-3528	1607	9	271	271	NUM
fnp-3528	1607	10	-	-	SYM
fnp-3528	1607	11	89	89	NUM
fnp-3528	1607	12	.	.	PUNCT
fnp-3528	1608	1	horikawa	horikawa	PROPN
fnp-3528	1608	2	,	,	PUNCT
fnp-3528	1608	3	m.	m.	NOUN
fnp-3528	1608	4	;	;	PUNCT
fnp-3528	1608	5	kato	kato	PROPN
fnp-3528	1608	6	,	,	PUNCT
fnp-3528	1608	7	y.	y.	PROPN
fnp-3528	1608	8	;	;	PUNCT
fnp-3528	1608	9	sugiyama	sugiyama	NOUN
fnp-3528	1608	10	,	,	PUNCT
fnp-3528	1608	11	y.	y.	PROPN
fnp-3528	1608	12	reduced	reduce	VERB
fnp-3528	1608	13	gastrointestinal	gastrointestinal	ADJ
fnp-3528	1608	14	toxicity	toxicity	NOUN
fnp-3528	1608	15	following	follow	VERB
fnp-3528	1608	16	inhibition	inhibition	NOUN
fnp-3528	1608	17	of	of	ADP
fnp-3528	1608	18	the	the	DET
fnp-3528	1608	19	biliary	biliary	ADJ
fnp-3528	1608	20	excretion	excretion	NOUN
fnp-3528	1608	21	of	of	ADP
fnp-3528	1608	22	irinotecan	irinotecan	NOUN
fnp-3528	1608	23	and	and	CCONJ
fnp-3528	1608	24	its	its	PRON
fnp-3528	1608	25	metabolites	metabolite	NOUN
fnp-3528	1608	26	by	by	ADP
fnp-3528	1608	27	probenecid	probenecid	PROPN
fnp-3528	1608	28	in	in	ADP
fnp-3528	1608	29	rats	rat	NOUN
fnp-3528	1608	30	.	.	PUNCT
fnp-3528	1609	1	pharm	pharm	NOUN
fnp-3528	1609	2	res	re	NOUN
fnp-3528	1609	3	2002	2002	NUM
fnp-3528	1609	4	,	,	PUNCT
fnp-3528	1609	5	19	19	NUM
fnp-3528	1609	6	,	,	PUNCT
fnp-3528	1609	7	1345	1345	NUM
fnp-3528	1609	8	-	-	SYM
fnp-3528	1609	9	53	53	NUM
fnp-3528	1609	10	.	.	PUNCT
fnp-3528	1610	1	smeets	smeet	NOUN
fnp-3528	1610	2	,	,	PUNCT
fnp-3528	1610	3	p.	p.	PROPN
fnp-3528	1610	4	h.	h.	PROPN
fnp-3528	1610	5	;	;	PUNCT
fnp-3528	1610	6	van	van	PROPN
fnp-3528	1610	7	aubel	aubel	PROPN
fnp-3528	1610	8	,	,	PUNCT
fnp-3528	1610	9	r.	r.	PROPN
fnp-3528	1610	10	a.	a.	PROPN
fnp-3528	1610	11	;	;	PUNCT
fnp-3528	1610	12	wouterse	wouterse	ADV
fnp-3528	1610	13	,	,	PUNCT
fnp-3528	1610	14	a.	a.	PROPN
fnp-3528	1610	15	c.	c.	PROPN
fnp-3528	1610	16	;	;	PUNCT
fnp-3528	1610	17	van	van	PROPN
fnp-3528	1610	18	den	den	PROPN
fnp-3528	1610	19	heuvel	heuvel	PROPN
fnp-3528	1610	20	,	,	PUNCT
fnp-3528	1610	21	j.	j.	PROPN
fnp-3528	1610	22	j.	j.	PROPN
fnp-3528	1610	23	;	;	PUNCT
fnp-3528	1610	24	russel	russel	PROPN
fnp-3528	1610	25	,	,	PUNCT
fnp-3528	1610	26	f.	f.	PROPN
fnp-3528	1610	27	g.	g.	PROPN
fnp-3528	1610	28	contribution	contribution	NOUN
fnp-3528	1610	29	of	of	ADP
fnp-3528	1610	30	multidrug	multidrug	NOUN
fnp-3528	1610	31	resistance	resistance	NOUN
fnp-3528	1610	32	protein	protein	NOUN
fnp-3528	1610	33	2	2	NUM
fnp-3528	1610	34	(	(	PUNCT
fnp-3528	1610	35	mrp2	mrp2	PROPN
fnp-3528	1610	36	/	/	SYM
fnp-3528	1610	37	abcc2	abcc2	NOUN
fnp-3528	1610	38	)	)	PUNCT
fnp-3528	1610	39	to	to	ADP
fnp-3528	1610	40	the	the	DET
fnp-3528	1610	41	renal	renal	ADJ
fnp-3528	1610	42	excretion	excretion	NOUN
fnp-3528	1610	43	of	of	ADP
fnp-3528	1610	44	p	p	NOUN
fnp-3528	1610	45	-	-	PUNCT
fnp-3528	1610	46	aminohippurate	aminohippurate	VERB
fnp-3528	1610	47	(	(	PUNCT
fnp-3528	1610	48	pah	pah	PROPN
fnp-3528	1610	49	)	)	PUNCT
fnp-3528	1610	50	and	and	CCONJ
fnp-3528	1610	51	identification	identification	NOUN
fnp-3528	1610	52	of	of	ADP
fnp-3528	1610	53	mrp4	mrp4	NOUN
fnp-3528	1610	54	(	(	PUNCT
fnp-3528	1610	55	abcc4	abcc4	NOUN
fnp-3528	1610	56	)	)	PUNCT
fnp-3528	1610	57	as	as	ADP
fnp-3528	1610	58	a	a	DET
fnp-3528	1610	59	novel	novel	NOUN
fnp-3528	1610	60	pah	pah	NOUN
fnp-3528	1610	61	transporter	transporter	NOUN
fnp-3528	1610	62	.	.	PUNCT
fnp-3528	1611	1	j	j	PROPN
fnp-3528	1611	2	am	be	AUX
fnp-3528	1611	3	soc	soc	NOUN
fnp-3528	1611	4	nephrol	nephrol	NOUN
fnp-3528	1611	5	2004	2004	NUM
fnp-3528	1611	6	,	,	PUNCT
fnp-3528	1611	7	15	15	NUM
fnp-3528	1611	8	,	,	PUNCT
fnp-3528	1611	9	2828	2828	NUM
fnp-3528	1611	10	-	-	SYM
fnp-3528	1611	11	35	35	NUM
fnp-3528	1611	12	.	.	PUNCT
fnp-3528	1612	1	dalpiaz	dalpiaz	PROPN
fnp-3528	1612	2	,	,	PUNCT
fnp-3528	1612	3	a.	a.	NOUN
fnp-3528	1612	4	;	;	PUNCT
fnp-3528	1612	5	pavan	pavan	PROPN
fnp-3528	1612	6	,	,	PUNCT
fnp-3528	1612	7	b.	b.	PROPN
fnp-3528	1612	8	nose	nose	PROPN
fnp-3528	1612	9	-	-	PUNCT
fnp-3528	1612	10	to	to	ADP
fnp-3528	1612	11	-	-	PUNCT
fnp-3528	1612	12	brain	brain	NOUN
fnp-3528	1612	13	delivery	delivery	NOUN
fnp-3528	1612	14	of	of	ADP
fnp-3528	1612	15	antiviral	antiviral	ADJ
fnp-3528	1612	16	drugs	drug	NOUN
fnp-3528	1612	17	:	:	PUNCT
fnp-3528	1612	18	a	a	DET
fnp-3528	1612	19	way	way	NOUN
fnp-3528	1612	20	to	to	PART
fnp-3528	1612	21	overcome	overcome	VERB
fnp-3528	1612	22	their	their	PRON
fnp-3528	1612	23	active	active	ADJ
fnp-3528	1612	24	efflux	efflux	NOUN
fnp-3528	1612	25	?	?	PUNCT
fnp-3528	1613	1	pharm	pharm	NOUN
fnp-3528	1613	2	2018	2018	NUM
fnp-3528	1613	3	,	,	PUNCT
fnp-3528	1613	4	10	10	NUM
fnp-3528	1613	5	,	,	PUNCT
fnp-3528	1613	6	39	39	NUM
fnp-3528	1613	7	.	.	PUNCT
fnp-3528	1614	1	zhou	zhou	PROPN
fnp-3528	1614	2	,	,	PUNCT
fnp-3528	1614	3	y.	y.	PROPN
fnp-3528	1614	4	;	;	PUNCT
fnp-3528	1614	5	hopper	hopper	NOUN
fnp-3528	1614	6	-	-	PUNCT
fnp-3528	1614	7	borge	borge	NOUN
fnp-3528	1614	8	,	,	PUNCT
fnp-3528	1614	9	e.	e.	PROPN
fnp-3528	1614	10	;	;	PUNCT
fnp-3528	1614	11	shen	shen	PROPN
fnp-3528	1614	12	,	,	PUNCT
fnp-3528	1614	13	t.	t.	PROPN
fnp-3528	1614	14	;	;	PUNCT
fnp-3528	1614	15	huang	huang	PROPN
fnp-3528	1614	16	,	,	PUNCT
fnp-3528	1614	17	x.	x.	PROPN
fnp-3528	1614	18	c.	c.	PROPN
fnp-3528	1614	19	;	;	PUNCT
fnp-3528	1614	20	shi	shi	PROPN
fnp-3528	1614	21	,	,	PUNCT
fnp-3528	1614	22	z.	z.	PROPN
fnp-3528	1614	23	;	;	PUNCT
fnp-3528	1614	24	kuang	kuang	PROPN
fnp-3528	1614	25	,	,	PUNCT
fnp-3528	1614	26	y.	y.	PROPN
fnp-3528	1614	27	h.	h.	PROPN
fnp-3528	1614	28	;	;	PUNCT
fnp-3528	1614	29	furukawa	furukawa	PROPN
fnp-3528	1614	30	,	,	PUNCT
fnp-3528	1614	31	t.	t.	PROPN
fnp-3528	1614	32	;	;	PUNCT
fnp-3528	1614	33	akiyama	akiyama	PROPN
fnp-3528	1614	34	,	,	PUNCT
fnp-3528	1614	35	s.	s.	PROPN
fnp-3528	1614	36	;	;	PUNCT
fnp-3528	1614	37	peng	peng	PROPN
fnp-3528	1614	38	,	,	PUNCT
fnp-3528	1614	39	x.	x.	PROPN
fnp-3528	1614	40	x.	x.	PROPN
fnp-3528	1614	41	;	;	PUNCT
fnp-3528	1614	42	ashby	ashby	PROPN
fnp-3528	1614	43	,	,	PUNCT
fnp-3528	1614	44	c.	c.	PROPN
fnp-3528	1614	45	r.	r.	PROPN
fnp-3528	1614	46	,	,	PUNCT
fnp-3528	1614	47	jr	jr	PROPN
fnp-3528	1614	48	.	.	PROPN
fnp-3528	1614	49	;	;	PUNCT
fnp-3528	1614	50	chen	chen	PROPN
fnp-3528	1614	51	,	,	PUNCT
fnp-3528	1614	52	x.	x.	NOUN
fnp-3528	1614	53	;	;	PUNCT
fnp-3528	1614	54	kruh	kruh	PROPN
fnp-3528	1614	55	,	,	PUNCT
fnp-3528	1614	56	g.	g.	PROPN
fnp-3528	1614	57	d.	d.	PROPN
fnp-3528	1614	58	;	;	PUNCT
fnp-3528	1614	59	chen	chen	PROPN
fnp-3528	1614	60	,	,	PUNCT
fnp-3528	1614	61	z.	z.	PROPN
fnp-3528	1614	62	s.	s.	PROPN
fnp-3528	1614	63	cepharanthine	cepharanthine	PROPN
fnp-3528	1614	64	is	be	AUX
fnp-3528	1614	65	a	a	DET
fnp-3528	1614	66	potent	potent	ADJ
fnp-3528	1614	67	reversal	reversal	NOUN
fnp-3528	1614	68	agent	agent	NOUN
fnp-3528	1614	69	for	for	ADP
fnp-3528	1614	70	mrp7(abcc10)-mediated	mrp7(abcc10)-mediate	VERB
fnp-3528	1614	71	multidrug	multidrug	NOUN
fnp-3528	1614	72	resistance	resistance	NOUN
fnp-3528	1614	73	.	.	PUNCT
fnp-3528	1615	1	biochem	biochem	PROPN
fnp-3528	1615	2	pharmacol	pharmacol	PROPN
fnp-3528	1615	3	2009	2009	NUM
fnp-3528	1615	4	,	,	PUNCT
fnp-3528	1615	5	77	77	NUM
fnp-3528	1615	6	,	,	PUNCT
fnp-3528	1615	7	993	993	NUM
fnp-3528	1615	8	-	-	SYM
fnp-3528	1615	9	1001	1001	NUM
fnp-3528	1615	10	.	.	PUNCT
fnp-3528	1616	1	saeed	saeed	PROPN
fnp-3528	1616	2	,	,	PUNCT
fnp-3528	1616	3	m.	m.	PROPN
fnp-3528	1616	4	e.	e.	PROPN
fnp-3528	1616	5	m.	m.	PROPN
fnp-3528	1616	6	;	;	PUNCT
fnp-3528	1616	7	boulos	boulo	NOUN
fnp-3528	1616	8	,	,	PUNCT
fnp-3528	1616	9	j.	j.	PROPN
fnp-3528	1616	10	c.	c.	PROPN
fnp-3528	1616	11	;	;	PUNCT
fnp-3528	1616	12	elhaboub	elhaboub	NOUN
fnp-3528	1616	13	,	,	PUNCT
fnp-3528	1616	14	g.	g.	PROPN
fnp-3528	1616	15	;	;	PUNCT
fnp-3528	1616	16	rigano	rigano	PROPN
fnp-3528	1616	17	,	,	PUNCT
fnp-3528	1616	18	d.	d.	PROPN
fnp-3528	1616	19	;	;	PUNCT
fnp-3528	1616	20	saab	saab	PROPN
fnp-3528	1616	21	,	,	PUNCT
fnp-3528	1616	22	a.	a.	NOUN
fnp-3528	1616	23	;	;	PUNCT
fnp-3528	1616	24	loizzo	loizzo	NOUN
fnp-3528	1616	25	,	,	PUNCT
fnp-3528	1616	26	m.	m.	NOUN
fnp-3528	1616	27	r.	r.	PROPN
fnp-3528	1616	28	;	;	PUNCT
fnp-3528	1616	29	hassan	hassan	PROPN
fnp-3528	1616	30	,	,	PUNCT
fnp-3528	1616	31	l.	l.	PROPN
fnp-3528	1616	32	e.	e.	PROPN
fnp-3528	1616	33	a.	a.	PROPN
fnp-3528	1616	34	;	;	PUNCT
fnp-3528	1616	35	sugimoto	sugimoto	PROPN
fnp-3528	1616	36	,	,	PUNCT
fnp-3528	1616	37	y.	y.	PROPN
fnp-3528	1616	38	;	;	PUNCT
fnp-3528	1616	39	piacente	piacente	NOUN
fnp-3528	1616	40	,	,	PUNCT
fnp-3528	1616	41	s.	s.	PROPN
fnp-3528	1616	42	;	;	PUNCT
fnp-3528	1616	43	tundis	tundi	NOUN
fnp-3528	1616	44	,	,	PUNCT
fnp-3528	1616	45	r.	r.	PROPN
fnp-3528	1616	46	;	;	PUNCT
fnp-3528	1616	47	yagi	yagi	PROPN
fnp-3528	1616	48	,	,	PUNCT
fnp-3528	1616	49	s.	s.	PROPN
fnp-3528	1616	50	;	;	PUNCT
fnp-3528	1616	51	khalid	khalid	PROPN
fnp-3528	1616	52	,	,	PUNCT
fnp-3528	1616	53	h.	h.	PROPN
fnp-3528	1616	54	;	;	PUNCT
fnp-3528	1616	55	efferth	efferth	ADJ
fnp-3528	1616	56	,	,	PUNCT
fnp-3528	1616	57	t.	t.	NOUN
fnp-3528	1616	58	cytotoxicity	cytotoxicity	NOUN
fnp-3528	1616	59	of	of	ADP
fnp-3528	1616	60	cucurbitacin	cucurbitacin	PROPN
fnp-3528	1616	61	e	e	NOUN
fnp-3528	1616	62	from	from	ADP
fnp-3528	1616	63	citrullus	citrullus	PROPN
fnp-3528	1616	64	colocynthis	colocynthis	PROPN
fnp-3528	1616	65	against	against	ADP
fnp-3528	1616	66	multidrug	multidrug	NOUN
fnp-3528	1616	67	-	-	PUNCT
fnp-3528	1616	68	resistant	resistant	ADJ
fnp-3528	1616	69	cancer	cancer	NOUN
fnp-3528	1616	70	cells	cell	NOUN
fnp-3528	1616	71	.	.	PUNCT
fnp-3528	1617	1	phytomedicine	phytomedicine	NOUN
fnp-3528	1617	2	2019	2019	NUM
fnp-3528	1617	3	,	,	PUNCT
fnp-3528	1617	4	62	62	NUM
fnp-3528	1617	5	,	,	PUNCT
fnp-3528	1617	6	152945	152945	NUM
fnp-3528	1617	7	.	.	PUNCT
fnp-3528	1618	1	horikawa	horikawa	PROPN
fnp-3528	1618	2	,	,	PUNCT
fnp-3528	1618	3	m.	m.	NOUN
fnp-3528	1618	4	;	;	PUNCT
fnp-3528	1618	5	kato	kato	PROPN
fnp-3528	1618	6	,	,	PUNCT
fnp-3528	1618	7	y.	y.	PROPN
fnp-3528	1618	8	;	;	PUNCT
fnp-3528	1618	9	tyson	tyson	PROPN
fnp-3528	1618	10	,	,	PUNCT
fnp-3528	1618	11	c.	c.	PROPN
fnp-3528	1618	12	a.	a.	PROPN
fnp-3528	1618	13	;	;	PUNCT
fnp-3528	1618	14	sugiyama	sugiyama	NOUN
fnp-3528	1618	15	,	,	PUNCT
fnp-3528	1618	16	y.	y.	PROPN
fnp-3528	1618	17	potential	potential	ADJ
fnp-3528	1618	18	cholestatic	cholestatic	ADJ
fnp-3528	1618	19	activity	activity	NOUN
fnp-3528	1618	20	of	of	ADP
fnp-3528	1618	21	various	various	ADJ
fnp-3528	1618	22	therapeutic	therapeutic	ADJ
fnp-3528	1618	23	agents	agent	NOUN
fnp-3528	1618	24	assessed	assess	VERB
fnp-3528	1618	25	by	by	ADP
fnp-3528	1618	26	bile	bile	NOUN
fnp-3528	1618	27	canalicular	canalicular	ADJ
fnp-3528	1618	28	membrane	membrane	NOUN
fnp-3528	1618	29	vesicles	vesicle	NOUN
fnp-3528	1618	30	isolated	isolate	VERB
fnp-3528	1618	31	from	from	ADP
fnp-3528	1618	32	rats	rat	NOUN
fnp-3528	1618	33	and	and	CCONJ
fnp-3528	1618	34	humans	human	NOUN
fnp-3528	1618	35	.	.	PUNCT
fnp-3528	1619	1	drug	drug	NOUN
fnp-3528	1619	2	metab	metab	PROPN
fnp-3528	1619	3	pharmacokinet	pharmacokinet	NOUN
fnp-3528	1619	4	2003	2003	NUM
fnp-3528	1619	5	,	,	PUNCT
fnp-3528	1619	6	18	18	NUM
fnp-3528	1619	7	,	,	PUNCT
fnp-3528	1619	8	16	16	NUM
fnp-3528	1619	9	-	-	SYM
fnp-3528	1619	10	22	22	NUM
fnp-3528	1619	11	.	.	PUNCT
fnp-3528	1620	1	bai	bai	PROPN
fnp-3528	1620	2	,	,	PUNCT
fnp-3528	1620	3	j.	j.	PROPN
fnp-3528	1620	4	;	;	PUNCT
fnp-3528	1620	5	lai	lai	PROPN
fnp-3528	1620	6	,	,	PUNCT
fnp-3528	1620	7	l.	l.	PROPN
fnp-3528	1620	8	;	;	PUNCT
fnp-3528	1620	9	yeo	yeo	PROPN
fnp-3528	1620	10	,	,	PUNCT
fnp-3528	1620	11	h.	h.	PROPN
fnp-3528	1620	12	c.	c.	PROPN
fnp-3528	1620	13	;	;	PUNCT
fnp-3528	1620	14	goh	goh	PROPN
fnp-3528	1620	15	,	,	PUNCT
fnp-3528	1620	16	b.	b.	PROPN
fnp-3528	1620	17	c.	c.	PROPN
fnp-3528	1620	18	;	;	PUNCT
fnp-3528	1620	19	tan	tan	PROPN
fnp-3528	1620	20	,	,	PUNCT
fnp-3528	1620	21	t.	t.	PROPN
fnp-3528	1620	22	m.	m.	NOUN
fnp-3528	1620	23	multidrug	multidrug	NOUN
fnp-3528	1620	24	resistance	resistance	NOUN
fnp-3528	1620	25	protein	protein	NOUN
fnp-3528	1620	26	4	4	NUM
fnp-3528	1620	27	(	(	PUNCT
fnp-3528	1620	28	mrp4	mrp4	NOUN
fnp-3528	1620	29	/	/	SYM
fnp-3528	1620	30	abcc4	abcc4	NOUN
fnp-3528	1620	31	)	)	PUNCT
fnp-3528	1620	32	mediates	mediate	NOUN
fnp-3528	1620	33	efflux	efflux	VERB
fnp-3528	1620	34	of	of	ADP
fnp-3528	1620	35	bimane	bimane	NOUN
fnp-3528	1620	36	-	-	PUNCT
fnp-3528	1620	37	glutathione	glutathione	NOUN
fnp-3528	1620	38	.	.	PUNCT
fnp-3528	1621	1	int	int	PROPN
fnp-3528	1621	2	j	j	PROPN
fnp-3528	1621	3	biochem	biochem	PROPN
fnp-3528	1621	4	cell	cell	NOUN
fnp-3528	1621	5	biol	biol	PROPN
fnp-3528	1621	6	2004	2004	NUM
fnp-3528	1621	7	,	,	PUNCT
fnp-3528	1621	8	36	36	NUM
fnp-3528	1621	9	,	,	PUNCT
fnp-3528	1621	10	247	247	NUM
fnp-3528	1621	11	-	-	SYM
fnp-3528	1621	12	57	57	NUM
fnp-3528	1621	13	.	.	PUNCT
fnp-3528	1622	1	videmann	videmann	PROPN
fnp-3528	1622	2	,	,	PUNCT
fnp-3528	1622	3	b.	b.	PROPN
fnp-3528	1622	4	;	;	PUNCT
fnp-3528	1622	5	mazallon	mazallon	NOUN
fnp-3528	1622	6	,	,	PUNCT
fnp-3528	1622	7	m.	m.	NOUN
fnp-3528	1622	8	;	;	PUNCT
fnp-3528	1622	9	prouillac	prouillac	PROPN
fnp-3528	1622	10	,	,	PUNCT
fnp-3528	1622	11	c.	c.	PROPN
fnp-3528	1622	12	;	;	PUNCT
fnp-3528	1622	13	delaforge	delaforge	NOUN
fnp-3528	1622	14	,	,	PUNCT
fnp-3528	1622	15	m.	m.	NOUN
fnp-3528	1622	16	;	;	PUNCT
fnp-3528	1622	17	lecoeur	lecoeur	PROPN
fnp-3528	1622	18	,	,	PUNCT
fnp-3528	1622	19	s.	s.	PROPN
fnp-3528	1622	20	abcc1	abcc1	PROPN
fnp-3528	1622	21	,	,	PUNCT
fnp-3528	1622	22	abcc2	abcc2	PROPN
fnp-3528	1622	23	and	and	CCONJ
fnp-3528	1622	24	abcc3	abcc3	NOUN
fnp-3528	1622	25	are	be	AUX
fnp-3528	1622	26	implicated	implicate	VERB
fnp-3528	1622	27	in	in	ADP
fnp-3528	1622	28	the	the	DET
fnp-3528	1622	29	transepithelial	transepithelial	ADJ
fnp-3528	1622	30	transport	transport	NOUN
fnp-3528	1622	31	of	of	ADP
fnp-3528	1622	32	the	the	DET
fnp-3528	1622	33	myco	myco	NOUN
fnp-3528	1622	34	-	-	PUNCT
fnp-3528	1622	35	estrogen	estrogen	NOUN
fnp-3528	1622	36	zearalenone	zearalenone	NOUN
fnp-3528	1622	37	and	and	CCONJ
fnp-3528	1622	38	its	its	PRON
fnp-3528	1622	39	major	major	ADJ
fnp-3528	1622	40	metabolites	metabolite	NOUN
fnp-3528	1622	41	.	.	PUNCT
fnp-3528	1623	1	toxicol	toxicol	PROPN
fnp-3528	1623	2	lett	lett	PROPN
fnp-3528	1623	3	2009	2009	NUM
fnp-3528	1623	4	,	,	PUNCT
fnp-3528	1623	5	190	190	NUM
fnp-3528	1623	6	,	,	PUNCT
fnp-3528	1623	7	215	215	NUM
fnp-3528	1623	8	-	-	SYM
fnp-3528	1623	9	23	23	NUM
fnp-3528	1623	10	.	.	PUNCT
fnp-3528	1624	1	tun	tun	NOUN
fnp-3528	1624	2	-	-	NOUN
fnp-3528	1624	3	yhong	yhong	ADJ
fnp-3528	1624	4	,	,	PUNCT
fnp-3528	1624	5	w.	w.	PROPN
fnp-3528	1624	6	;	;	PUNCT
fnp-3528	1624	7	chinpaisal	chinpaisal	PROPN
fnp-3528	1624	8	,	,	PUNCT
fnp-3528	1624	9	c.	c.	PROPN
fnp-3528	1624	10	;	;	PUNCT
fnp-3528	1624	11	pamonsinlapatham	pamonsinlapatham	PROPN
fnp-3528	1624	12	,	,	PUNCT
fnp-3528	1624	13	p.	p.	PROPN
fnp-3528	1624	14	;	;	PUNCT
fnp-3528	1624	15	kaewkitichai	kaewkitichai	PROPN
fnp-3528	1624	16	,	,	PUNCT
fnp-3528	1624	17	s.	s.	PROPN
fnp-3528	1624	18	tenofovir	tenofovir	PROPN
fnp-3528	1624	19	disoproxil	disoproxil	VERB
fnp-3528	1624	20	fumarate	fumarate	NOUN
fnp-3528	1624	21	is	be	AUX
fnp-3528	1624	22	a	a	DET
fnp-3528	1624	23	new	new	ADJ
fnp-3528	1624	24	substrate	substrate	NOUN
fnp-3528	1624	25	of	of	ADP
fnp-3528	1624	26	atp	atp	NOUN
fnp-3528	1624	27	-	-	PUNCT
fnp-3528	1624	28	binding	bind	VERB
fnp-3528	1624	29	cassette	cassette	NOUN
fnp-3528	1624	30	subfamily	subfamily	ADV
fnp-3528	1624	31	c	c	NOUN
fnp-3528	1624	32	member	member	NOUN
fnp-3528	1624	33	11	11	NUM
fnp-3528	1624	34	.	.	PUNCT
fnp-3528	1625	1	antimicrob	antimicrob	PROPN
fnp-3528	1625	2	agents	agents	PROPN
fnp-3528	1625	3	chemother	chemother	PROPN
fnp-3528	1625	4	2017	2017	NUM
fnp-3528	1625	5	,	,	PUNCT
fnp-3528	1625	6	61	61	NUM
fnp-3528	1625	7	,	,	PUNCT
fnp-3528	1625	8	e01725	e01725	NOUN
fnp-3528	1625	9	-	-	X
fnp-3528	1625	10	16	16	NUM
fnp-3528	1625	11	.	.	PUNCT
fnp-3528	1626	1	copyright	copyright	NOUN
fnp-3528	1626	2	:	:	PUNCT
fnp-3528	1626	3	©	©	PROPN
fnp-3528	1626	4	2021	2021	NUM
fnp-3528	1626	5	the	the	DET
fnp-3528	1626	6	author(s	author(s	NOUN
fnp-3528	1626	7	)	)	PUNCT
fnp-3528	1626	8	.	.	PUNCT
fnp-3528	1627	1	this	this	PRON
fnp-3528	1627	2	is	be	AUX
fnp-3528	1627	3	an	an	DET
fnp-3528	1627	4	open	open	ADJ
fnp-3528	1627	5	access	access	NOUN
fnp-3528	1627	6	article	article	NOUN
fnp-3528	1627	7	distributed	distribute	VERB
fnp-3528	1627	8	under	under	ADP
fnp-3528	1627	9	the	the	DET
fnp-3528	1627	10	terms	term	NOUN
fnp-3528	1627	11	of	of	ADP
fnp-3528	1627	12	the	the	DET
fnp-3528	1627	13	creative	creative	ADJ
fnp-3528	1627	14	commons	common	NOUN
fnp-3528	1627	15	attribution	attribution	NOUN
fnp-3528	1627	16	4.0	4.0	NUM
fnp-3528	1627	17	international	international	ADJ
fnp-3528	1627	18	license	license	NOUN
fnp-3528	1627	19	(	(	PUNCT
fnp-3528	1627	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3528	1627	21	)	)	PUNCT
fnp-3528	1627	22	,	,	PUNCT
fnp-3528	1627	23	which	which	PRON
fnp-3528	1627	24	permits	permit	VERB
fnp-3528	1627	25	unrestricted	unrestricted	ADJ
fnp-3528	1627	26	use	use	NOUN
fnp-3528	1627	27	,	,	PUNCT
fnp-3528	1627	28	distribution	distribution	NOUN
fnp-3528	1627	29	,	,	PUNCT
fnp-3528	1627	30	and	and	CCONJ
fnp-3528	1627	31	reproduction	reproduction	NOUN
fnp-3528	1627	32	in	in	ADP
fnp-3528	1627	33	any	any	DET
fnp-3528	1627	34	medium	medium	NOUN
fnp-3528	1627	35	,	,	PUNCT
fnp-3528	1627	36	provided	provide	VERB
fnp-3528	1627	37	the	the	DET
fnp-3528	1627	38	original	original	ADJ
fnp-3528	1627	39	author	author	NOUN
fnp-3528	1627	40	and	and	CCONJ
fnp-3528	1627	41	source	source	NOUN
fnp-3528	1627	42	are	be	AUX
fnp-3528	1627	43	credited	credit	VERB
fnp-3528	1627	44	,	,	PUNCT
fnp-3528	1627	45	a	a	DET
fnp-3528	1627	46	link	link	NOUN
fnp-3528	1627	47	to	to	ADP
fnp-3528	1627	48	the	the	DET
fnp-3528	1627	49	creative	creative	ADJ
fnp-3528	1627	50	commons	common	NOUN
fnp-3528	1627	51	license	license	NOUN
fnp-3528	1627	52	is	be	AUX
fnp-3528	1627	53	provided	provide	VERB
fnp-3528	1627	54	,	,	PUNCT
fnp-3528	1627	55	and	and	CCONJ
fnp-3528	1627	56	any	any	DET
fnp-3528	1627	57	changes	change	NOUN
fnp-3528	1627	58	are	be	AUX
fnp-3528	1627	59	indicated	indicate	VERB
fnp-3528	1627	60	.	.	PUNCT
fnp-3528	1628	1	the	the	DET
fnp-3528	1628	2	creative	creative	ADJ
fnp-3528	1628	3	commons	common	NOUN
fnp-3528	1628	4	public	public	ADJ
fnp-3528	1628	5	domain	domain	NOUN
fnp-3528	1628	6	dedication	dedication	NOUN
fnp-3528	1628	7	waiver	waiver	NOUN
fnp-3528	1628	8	(	(	PUNCT
fnp-3528	1628	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3528	1628	10	)	)	PUNCT
fnp-3528	1628	11	applies	apply	VERB
fnp-3528	1628	12	to	to	ADP
fnp-3528	1628	13	the	the	DET
fnp-3528	1628	14	data	datum	NOUN
fnp-3528	1628	15	made	make	VERB
fnp-3528	1628	16	available	available	ADJ
fnp-3528	1628	17	in	in	ADP
fnp-3528	1628	18	this	this	DET
fnp-3528	1628	19	article	article	NOUN
fnp-3528	1628	20	,	,	PUNCT
fnp-3528	1628	21	unless	unless	SCONJ
fnp-3528	1628	22	otherwise	otherwise	ADV
fnp-3528	1628	23	stated	state	VERB
fnp-3528	1628	24	.	.	PUNCT