id	sid	tid	token	lemma	pos
fnp-3671	1	1	61st	61st	ADJ
fnp-3671	1	2	annual	annual	ADJ
fnp-3671	1	3	meeting	meeting	NOUN
fnp-3671	1	4	of	of	ADP
fnp-3671	1	5	the	the	DET
fnp-3671	1	6	canadian	canadian	PROPN
fnp-3671	1	7	association	association	PROPN
fnp-3671	1	8	of	of	ADP
fnp-3671	1	9	neuropathologists	neuropathologists	PROPN
fnp-3671	1	10	association	association	PROPN
fnp-3671	1	11	canadienne	canadienne	PROPN
fnp-3671	1	12	des	des	PROPN
fnp-3671	1	13	neuropathologistes	neuropathologistes	PROPN
fnp-3671	1	14	(	(	PUNCT
fnp-3671	1	15	canp	canp	NOUN
fnp-3671	1	16	-	-	PUNCT
fnp-3671	1	17	acnp	acnp	NOUN
fnp-3671	1	18	)	)	PUNCT
fnp-3671	1	19	meeting	meeting	NOUN
fnp-3671	1	20	abstracts	abstract	NOUN
fnp-3671	1	21	feel	feel	VERB
fnp-3671	1	22	free	free	ADJ
fnp-3671	1	23	to	to	PART
fnp-3671	1	24	add	add	VERB
fnp-3671	1	25	comments	comment	NOUN
fnp-3671	1	26	by	by	ADP
fnp-3671	1	27	clicking	click	VERB
fnp-3671	1	28	these	these	DET
fnp-3671	1	29	icons	icon	NOUN
fnp-3671	1	30	on	on	ADP
fnp-3671	1	31	the	the	DET
fnp-3671	1	32	sidebar	sidebar	NOUN
fnp-3671	1	33	free	free	ADJ
fnp-3671	1	34	neuropathology	neuropathology	PROPN
fnp-3671	1	35	2:29	2:29	NUM
fnp-3671	1	36	(	(	PUNCT
fnp-3671	1	37	2021	2021	NUM
fnp-3671	1	38	)	)	PUNCT
fnp-3671	1	39	meeting	meeting	NOUN
fnp-3671	1	40	abstracts	abstract	VERB
fnp-3671	1	41	61st	61st	ADJ
fnp-3671	1	42	annual	annual	ADJ
fnp-3671	1	43	meeting	meeting	NOUN
fnp-3671	1	44	of	of	ADP
fnp-3671	1	45	the	the	DET
fnp-3671	1	46	canadian	canadian	PROPN
fnp-3671	1	47	association	association	PROPN
fnp-3671	1	48	of	of	ADP
fnp-3671	1	49	neuropathologists	neuropathologists	PROPN
fnp-3671	1	50	association	association	PROPN
fnp-3671	1	51	canadienne	canadienne	PROPN
fnp-3671	1	52	des	des	PROPN
fnp-3671	1	53	neuropathologistes	neuropathologistes	PROPN
fnp-3671	1	54	(	(	PUNCT
fnp-3671	1	55	canp	canp	NOUN
fnp-3671	1	56	-	-	PUNCT
fnp-3671	1	57	acnp	acnp	NOUN
fnp-3671	1	58	)	)	PUNCT
fnp-3671	1	59	meeting	meeting	NOUN
fnp-3671	1	60	abstracts	abstract	VERB
fnp-3671	1	61	october	october	PROPN
fnp-3671	1	62	14–16	14–16	NUM
fnp-3671	1	63	,	,	PUNCT
fnp-3671	1	64	2021	2021	NUM
fnp-3671	1	65	submitted	submit	VERB
fnp-3671	1	66	:	:	PUNCT
fnp-3671	1	67	26	26	NUM
fnp-3671	1	68	october	october	NOUN
fnp-3671	1	69	2021	2021	NUM
fnp-3671	1	70	accepted	accept	VERB
fnp-3671	1	71	:	:	PUNCT
fnp-3671	1	72	27	27	NUM
fnp-3671	1	73	october	october	NOUN
fnp-3671	1	74	2021	2021	NUM
fnp-3671	1	75	published	publish	VERB
fnp-3671	1	76	:	:	PUNCT
fnp-3671	1	77	29	29	NUM
fnp-3671	1	78	october	october	NOUN
fnp-3671	1	79	2021	2021	NUM
fnp-3671	1	80	  	  	SPACE
fnp-3671	1	81	the	the	DET
fnp-3671	1	82	canadian	canadian	PROPN
fnp-3671	1	83	association	association	NOUN
fnp-3671	1	84	of	of	ADP
fnp-3671	1	85	neuropathologist	neuropathologist	ADJ
fnp-3671	1	86	–	–	PUNCT
fnp-3671	1	87	association	association	PROPN
fnp-3671	1	88	canadienne	canadienne	PROPN
fnp-3671	1	89	des	des	X
fnp-3671	1	90	neuropathologistes	neuropathologistes	PROPN
fnp-3671	1	91	(	(	PUNCT
fnp-3671	1	92	canp	canp	NOUN
fnp-3671	1	93	-	-	PUNCT
fnp-3671	1	94	acnp	acnp	NOUN
fnp-3671	1	95	)	)	PUNCT
fnp-3671	1	96	held	hold	VERB
fnp-3671	1	97	their	their	PRON
fnp-3671	1	98	61st	61st	ADJ
fnp-3671	1	99	annual	annual	ADJ
fnp-3671	1	100	meeting	meeting	NOUN
fnp-3671	1	101	via	via	ADP
fnp-3671	1	102	zoom	zoom	NUM
fnp-3671	1	103	from	from	ADP
fnp-3671	1	104	october	october	PROPN
fnp-3671	1	105	14th	14th	NOUN
fnp-3671	1	106	to	to	ADP
fnp-3671	1	107	16th	16th	NOUN
fnp-3671	1	108	,	,	PUNCT
fnp-3671	1	109	2021	2021	NUM
fnp-3671	1	110	,	,	PUNCT
fnp-3671	1	111	under	under	ADP
fnp-3671	1	112	the	the	DET
fnp-3671	1	113	leadership	leadership	NOUN
fnp-3671	1	114	of	of	ADP
fnp-3671	1	115	dr	dr	PROPN
fnp-3671	1	116	.	.	PROPN
fnp-3671	1	117	peter	peter	PROPN
fnp-3671	1	118	gould	gould	PROPN
fnp-3671	1	119	,	,	PUNCT
fnp-3671	1	120	president	president	NOUN
fnp-3671	1	121	of	of	ADP
fnp-3671	1	122	the	the	DET
fnp-3671	1	123	canp	canp	NOUN
fnp-3671	1	124	-	-	PUNCT
fnp-3671	1	125	acnp	acnp	ADJ
fnp-3671	1	126	,	,	PUNCT
fnp-3671	1	127	dr	dr	PROPN
fnp-3671	1	128	.	.	PROPN
fnp-3671	1	129	peter	peter	PROPN
fnp-3671	1	130	schutz	schutz	PROPN
fnp-3671	1	131	,	,	PUNCT
fnp-3671	1	132	secretary	secretary	NOUN
fnp-3671	1	133	treasurer	treasurer	NOUN
fnp-3671	1	134	of	of	ADP
fnp-3671	1	135	the	the	DET
fnp-3671	1	136	canp	canp	NOUN
fnp-3671	1	137	-	-	PUNCT
fnp-3671	1	138	acnp	acnp	NOUN
fnp-3671	1	139	,	,	PUNCT
fnp-3671	1	140	and	and	CCONJ
fnp-3671	1	141	with	with	ADP
fnp-3671	1	142	technical	technical	ADJ
fnp-3671	1	143	support	support	NOUN
fnp-3671	1	144	from	from	ADP
fnp-3671	1	145	canp	canp	PROPN
fnp-3671	1	146	administrators	administrator	NOUN
fnp-3671	1	147	heather	heather	PROPN
fnp-3671	1	148	dow	dow	PROPN
fnp-3671	1	149	and	and	CCONJ
fnp-3671	1	150	colleen	colleen	PROPN
fnp-3671	1	151	fifield	fifield	NOUN
fnp-3671	1	152	.	.	PUNCT
fnp-3671	2	1	the	the	DET
fnp-3671	2	2	academic	academic	ADJ
fnp-3671	2	3	program	program	NOUN
fnp-3671	2	4	comprised	comprise	VERB
fnp-3671	2	5	17	17	NUM
fnp-3671	2	6	scientific	scientific	ADJ
fnp-3671	2	7	abstracts	abstract	NOUN
fnp-3671	2	8	,	,	PUNCT
fnp-3671	2	9	8	8	NUM
fnp-3671	2	10	unknown	unknown	ADJ
fnp-3671	2	11	cases	case	NOUN
fnp-3671	2	12	,	,	PUNCT
fnp-3671	2	13	the	the	DET
fnp-3671	2	14	presidential	presidential	ADJ
fnp-3671	2	15	symposium	symposium	NOUN
fnp-3671	2	16	on	on	ADP
fnp-3671	2	17	epilepsy	epilepsy	NOUN
fnp-3671	2	18	and	and	CCONJ
fnp-3671	2	19	neoplasms	neoplasm	NOUN
fnp-3671	2	20	,	,	PUNCT
fnp-3671	2	21	and	and	CCONJ
fnp-3671	2	22	a	a	DET
fnp-3671	2	23	neuropathology	neuropathology	NOUN
fnp-3671	2	24	in	in	ADP
fnp-3671	2	25	practice	practice	NOUN
fnp-3671	2	26	session	session	NOUN
fnp-3671	2	27	on	on	ADP
fnp-3671	2	28	the	the	DET
fnp-3671	2	29	implementation	implementation	NOUN
fnp-3671	2	30	of	of	ADP
fnp-3671	2	31	the	the	DET
fnp-3671	2	32	new	new	ADJ
fnp-3671	2	33	who	who	PRON
fnp-3671	2	34	classification	classification	NOUN
fnp-3671	2	35	of	of	ADP
fnp-3671	2	36	cns	cns	PROPN
fnp-3671	2	37	neoplasms	neoplasm	NOUN
fnp-3671	2	38	in	in	ADP
fnp-3671	2	39	canada	canada	PROPN
fnp-3671	2	40	.	.	PUNCT
fnp-3671	3	1	digital	digital	ADJ
fnp-3671	3	2	pathology	pathology	NOUN
fnp-3671	3	3	images	image	VERB
fnp-3671	3	4	from	from	ADP
fnp-3671	3	5	the	the	DET
fnp-3671	3	6	8	8	NUM
fnp-3671	3	7	unknown	unknown	ADJ
fnp-3671	3	8	cases	case	NOUN
fnp-3671	3	9	are	be	AUX
fnp-3671	3	10	available	available	ADJ
fnp-3671	3	11	for	for	ADP
fnp-3671	3	12	viewing	view	VERB
fnp-3671	3	13	online	online	ADV
fnp-3671	3	14	(	(	PUNCT
fnp-3671	3	15	www.canp.ca	www.canp.ca	NOUN
fnp-3671	3	16	)	)	PUNCT
fnp-3671	3	17	.	.	PUNCT
fnp-3671	4	1	the	the	DET
fnp-3671	4	2	unknown	unknown	ADJ
fnp-3671	4	3	case	case	NOUN
fnp-3671	4	4	sessions	session	NOUN
fnp-3671	4	5	were	be	AUX
fnp-3671	4	6	moderated	moderate	VERB
fnp-3671	4	7	by	by	ADP
fnp-3671	4	8	dr	dr	PROPN
fnp-3671	4	9	.	.	PROPN
fnp-3671	4	10	andrew	andrew	PROPN
fnp-3671	4	11	gao	gao	PROPN
fnp-3671	4	12	.	.	PUNCT
fnp-3671	5	1	the	the	DET
fnp-3671	5	2	presidential	presidential	ADJ
fnp-3671	5	3	symposium	symposium	NOUN
fnp-3671	5	4	2021	2021	NUM
fnp-3671	5	5	on	on	ADP
fnp-3671	5	6	epilepsy	epilepsy	NOUN
fnp-3671	5	7	and	and	CCONJ
fnp-3671	5	8	neoplasms	neoplasm	NOUN
fnp-3671	5	9	featured	feature	VERB
fnp-3671	5	10	the	the	DET
fnp-3671	5	11	david	david	PROPN
fnp-3671	5	12	robertson	robertson	PROPN
fnp-3671	5	13	lecture	lecture	NOUN
fnp-3671	5	14	given	give	VERB
fnp-3671	5	15	by	by	ADP
fnp-3671	5	16	dr	dr	PROPN
fnp-3671	5	17	.	.	PROPN
fnp-3671	5	18	eleonora	eleonora	PROPN
fnp-3671	5	19	aronica	aronica	PROPN
fnp-3671	5	20	entitled	entitle	VERB
fnp-3671	5	21	evolving	evolve	VERB
fnp-3671	5	22	classification	classification	NOUN
fnp-3671	5	23	of	of	ADP
fnp-3671	5	24	epilepsy	epilepsy	NOUN
fnp-3671	5	25	-	-	PUNCT
fnp-3671	5	26	associated	associate	VERB
fnp-3671	5	27	tumors	tumor	NOUN
fnp-3671	5	28	:	:	PUNCT
fnp-3671	5	29	understanding	understanding	NOUN
fnp-3671	5	30	epileptogenesis	epileptogenesis	NOUN
fnp-3671	5	31	,	,	PUNCT
fnp-3671	5	32	the	the	DET
fnp-3671	5	33	gordon	gordon	PROPN
fnp-3671	5	34	mathieson	mathieson	PROPN
fnp-3671	5	35	lecture	lecture	NOUN
fnp-3671	5	36	delivered	deliver	VERB
fnp-3671	5	37	by	by	ADP
fnp-3671	5	38	dr	dr	PROPN
fnp-3671	5	39	.	.	PROPN
fnp-3671	5	40	harvey	harvey	PROPN
fnp-3671	5	41	sarnat	sarnat	PROPN
fnp-3671	5	42	on	on	ADP
fnp-3671	5	43	why	why	SCONJ
fnp-3671	5	44	are	be	AUX
fnp-3671	5	45	some	some	DET
fnp-3671	5	46	cerebral	cerebral	ADJ
fnp-3671	5	47	malformations	malformation	NOUN
fnp-3671	5	48	more	more	ADJ
fnp-3671	5	49	epileptogenic	epileptogenic	ADJ
fnp-3671	5	50	than	than	ADP
fnp-3671	5	51	others	other	NOUN
fnp-3671	5	52	?	?	PUNCT
fnp-3671	6	1	clues	clue	NOUN
fnp-3671	6	2	from	from	ADP
fnp-3671	6	3	developmental	developmental	ADJ
fnp-3671	6	4	neuropathology	neuropathology	NOUN
fnp-3671	6	5	,	,	PUNCT
fnp-3671	6	6	and	and	CCONJ
fnp-3671	6	7	the	the	DET
fnp-3671	6	8	jerzy	jerzy	PROPN
fnp-3671	6	9	olszewsky	olszewsky	ADJ
fnp-3671	6	10	lecture	lecture	NOUN
fnp-3671	6	11	presented	present	VERB
fnp-3671	6	12	by	by	ADP
fnp-3671	6	13	dr	dr	PROPN
fnp-3671	6	14	.	.	PROPN
fnp-3671	6	15	maria	maria	PROPN
fnp-3671	6	16	thom	thom	PROPN
fnp-3671	6	17	on	on	ADP
fnp-3671	6	18	neuropathology	neuropathology	NOUN
fnp-3671	6	19	in	in	ADP
fnp-3671	6	20	sudden	sudden	ADJ
fnp-3671	6	21	and	and	CCONJ
fnp-3671	6	22	unexpected	unexpected	ADJ
fnp-3671	6	23	death	death	NOUN
fnp-3671	6	24	in	in	ADP
fnp-3671	6	25	epilepsy	epilepsy	NOUN
fnp-3671	6	26	and	and	CCONJ
fnp-3671	6	27	future	future	ADJ
fnp-3671	6	28	directions	direction	NOUN
fnp-3671	6	29	.	.	PUNCT
fnp-3671	7	1	the	the	DET
fnp-3671	7	2	program	program	NOUN
fnp-3671	7	3	was	be	AUX
fnp-3671	7	4	completed	complete	VERB
fnp-3671	7	5	dr	dr	PROPN
fnp-3671	7	6	.	.	PROPN
fnp-3671	7	7	george	george	PROPN
fnp-3671	7	8	ibrahim	ibrahim	PROPN
fnp-3671	7	9	’s	’s	PART
fnp-3671	7	10	lecture	lecture	NOUN
fnp-3671	7	11	on	on	ADP
fnp-3671	7	12	epilepsy	epilepsy	NOUN
fnp-3671	7	13	as	as	ADP
fnp-3671	7	14	a	a	DET
fnp-3671	7	15	network	network	NOUN
fnp-3671	7	16	disorder	disorder	NOUN
fnp-3671	7	17	.	.	PUNCT
fnp-3671	8	1	the	the	DET
fnp-3671	8	2	mary	mary	PROPN
fnp-3671	8	3	tom	tom	PROPN
fnp-3671	8	4	award	award	PROPN
fnp-3671	8	5	for	for	ADP
fnp-3671	8	6	best	good	ADJ
fnp-3671	8	7	clinical	clinical	ADJ
fnp-3671	8	8	science	science	NOUN
fnp-3671	8	9	presentation	presentation	NOUN
fnp-3671	8	10	by	by	ADP
fnp-3671	8	11	a	a	DET
fnp-3671	8	12	trainee	trainee	NOUN
fnp-3671	8	13	went	go	VERB
fnp-3671	8	14	to	to	ADP
fnp-3671	8	15	dr	dr	PROPN
fnp-3671	8	16	.	.	PROPN
fnp-3671	8	17	suzy	suzy	PROPN
fnp-3671	8	18	kosteniuk	kosteniuk	PROPN
fnp-3671	8	19	(	(	PUNCT
fnp-3671	8	20	supervisor	supervisor	NOUN
fnp-3671	8	21	dr	dr	PROPN
fnp-3671	8	22	.	.	PROPN
fnp-3671	8	23	s.	s.	PROPN
fnp-3671	8	24	das	das	PROPN
fnp-3671	8	25	)	)	PUNCT
fnp-3671	8	26	,	,	PUNCT
fnp-3671	8	27	and	and	CCONJ
fnp-3671	8	28	the	the	DET
fnp-3671	8	29	morrison	morrison	PROPN
fnp-3671	8	30	h.	h.	PROPN
fnp-3671	8	31	finlayson	finlayson	PROPN
fnp-3671	8	32	award	award	PROPN
fnp-3671	8	33	for	for	ADP
fnp-3671	8	34	best	good	ADJ
fnp-3671	8	35	basic	basic	ADJ
fnp-3671	8	36	science	science	NOUN
fnp-3671	8	37	presentation	presentation	NOUN
fnp-3671	8	38	by	by	ADP
fnp-3671	8	39	a	a	DET
fnp-3671	8	40	trainee	trainee	NOUN
fnp-3671	8	41	was	be	AUX
fnp-3671	8	42	won	win	VERB
fnp-3671	8	43	by	by	ADP
fnp-3671	8	44	dr	dr	PROPN
fnp-3671	8	45	.	.	PROPN
fnp-3671	8	46	nicole	nicole	PROPN
fnp-3671	8	47	schwab	schwab	PROPN
fnp-3671	8	48	(	(	PUNCT
fnp-3671	8	49	supervisor	supervisor	NOUN
fnp-3671	8	50	dr	dr	PROPN
fnp-3671	8	51	.	.	PROPN
fnp-3671	8	52	l.n	l.n	PROPN
fnp-3671	8	53	.	.	PROPN
fnp-3671	8	54	hazrati	hazrati	PROPN
fnp-3671	8	55	)	)	PUNCT
fnp-3671	8	56	.	.	PUNCT
fnp-3671	9	1	the	the	DET
fnp-3671	9	2	following	follow	VERB
fnp-3671	9	3	abstracts	abstract	NOUN
fnp-3671	9	4	were	be	AUX
fnp-3671	9	5	presented	present	VERB
fnp-3671	9	6	at	at	ADP
fnp-3671	9	7	the	the	DET
fnp-3671	9	8	61st	61st	ADJ
fnp-3671	9	9	annual	annual	ADJ
fnp-3671	9	10	meeting	meeting	NOUN
fnp-3671	9	11	of	of	ADP
fnp-3671	9	12	the	the	DET
fnp-3671	9	13	canadian	canadian	PROPN
fnp-3671	9	14	association	association	NOUN
fnp-3671	9	15	of	of	ADP
fnp-3671	9	16	neuropathologists	neuropathologist	NOUN
fnp-3671	9	17	–	–	PUNCT
fnp-3671	9	18	association	association	PROPN
fnp-3671	9	19	candienne	candienne	PROPN
fnp-3671	9	20	des	des	PROPN
fnp-3671	9	21	neuropathologistes	neuropathologistes	PROPN
fnp-3671	9	22	(	(	PUNCT
fnp-3671	9	23	canp	canp	NOUN
fnp-3671	9	24	-	-	PUNCT
fnp-3671	9	25	acnp	acnp	NOUN
fnp-3671	9	26	)	)	PUNCT
fnp-3671	9	27	in	in	ADP
fnp-3671	9	28	october	october	PROPN
fnp-3671	9	29	2021	2021	NUM
fnp-3671	9	30	.	.	PUNCT
fnp-3671	10	1	https://doi.org/10.17879/freeneuropathology-2021-3671	https://doi.org/10.17879/freeneuropathology-2021-3671	NOUN
fnp-3671	10	2	keywords	keyword	NOUN
fnp-3671	10	3	:	:	PUNCT
fnp-3671	10	4	canadian	canadian	ADJ
fnp-3671	10	5	association	association	NOUN
fnp-3671	10	6	of	of	ADP
fnp-3671	10	7	neuropathologists	neuropathologist	NOUN
fnp-3671	10	8	,	,	PUNCT
fnp-3671	10	9	canp	canp	NOUN
fnp-3671	10	10	,	,	PUNCT
fnp-3671	10	11	meeting	meet	VERB
fnp-3671	10	12	abstracts	abstract	NOUN
fnp-3671	10	13	,	,	PUNCT
fnp-3671	10	14	61st	61st	ADJ
fnp-3671	10	15	meeting	meeting	NOUN
fnp-3671	10	16	oct	oct	PROPN
fnp-3671	10	17	.	.	PROPN
fnp-3671	10	18	2021	2021	NUM
fnp-3671	10	19	contents	content	NOUN
fnp-3671	10	20	abstract	abstract	ADJ
fnp-3671	10	21	1	1	NUM
fnp-3671	10	22	:	:	PUNCT
fnp-3671	10	23	histologic	histologic	ADJ
fnp-3671	10	24	and	and	CCONJ
fnp-3671	10	25	clinical	clinical	ADJ
fnp-3671	10	26	spectrum	spectrum	NOUN
fnp-3671	10	27	of	of	ADP
fnp-3671	10	28	brain	brain	NOUN
fnp-3671	10	29	tumours	tumour	NOUN
fnp-3671	10	30	harbouring	harbour	VERB
fnp-3671	10	31	fgfr3	fgfr3	NOUN
fnp-3671	10	32	-	-	PUNCT
fnp-3671	10	33	tacc3	tacc3	PROPN
fnp-3671	10	34	fusions	fusion	NOUN
fnp-3671	10	35	abstract	abstract	ADJ
fnp-3671	10	36	2	2	NUM
fnp-3671	10	37	:	:	PUNCT
fnp-3671	10	38	ganglion	ganglion	NOUN
fnp-3671	10	39	cell	cell	NOUN
fnp-3671	10	40	maturational	maturational	ADJ
fnp-3671	10	41	markers	marker	NOUN
fnp-3671	10	42	in	in	ADP
fnp-3671	10	43	peripheral	peripheral	ADJ
fnp-3671	10	44	neuroblastic	neuroblastic	ADJ
fnp-3671	10	45	tumours	tumour	NOUN
fnp-3671	10	46	of	of	ADP
fnp-3671	10	47	children	child	NOUN
fnp-3671	10	48	abstract	abstract	ADJ
fnp-3671	10	49	3	3	NUM
fnp-3671	10	50	:	:	PUNCT
fnp-3671	10	51	long	long	ADJ
fnp-3671	10	52	term	term	NOUN
fnp-3671	10	53	disease	disease	NOUN
fnp-3671	10	54	-	-	PUNCT
fnp-3671	10	55	free	free	ADJ
fnp-3671	10	56	survival	survival	NOUN
fnp-3671	10	57	after	after	ADP
fnp-3671	10	58	surgical	surgical	ADJ
fnp-3671	10	59	resection	resection	NOUN
fnp-3671	10	60	only	only	ADV
fnp-3671	10	61	:	:	PUNCT
fnp-3671	10	62	malignant	malignant	ADJ
fnp-3671	10	63	idh	idh	NOUN
fnp-3671	10	64	-	-	PUNCT
fnp-3671	10	65	mutated	mutate	VERB
fnp-3671	10	66	astrocytoma	astrocytoma	NOUN
fnp-3671	10	67	versus	versus	ADP
fnp-3671	10	68	ganglioglioma	ganglioglioma	ADJ
fnp-3671	10	69	abstract	abstract	ADJ
fnp-3671	10	70	4	4	NUM
fnp-3671	10	71	:	:	PUNCT
fnp-3671	10	72	diagnostic	diagnostic	ADJ
fnp-3671	10	73	challenges	challenge	NOUN
fnp-3671	10	74	in	in	ADP
fnp-3671	10	75	unusual	unusual	ADJ
fnp-3671	10	76	high	high	ADJ
fnp-3671	10	77	-	-	PUNCT
fnp-3671	10	78	grade	grade	NOUN
fnp-3671	10	79	gliomas	glioma	NOUN
fnp-3671	10	80	abstract	abstract	ADJ
fnp-3671	10	81	5	5	NUM
fnp-3671	10	82	:	:	PUNCT
fnp-3671	10	83	regional	regional	ADJ
fnp-3671	10	84	variability	variability	NOUN
fnp-3671	10	85	of	of	ADP
fnp-3671	10	86	α	α	NOUN
fnp-3671	10	87	-	-	PUNCT
fnp-3671	10	88	synuclein	synuclein	NOUN
fnp-3671	10	89	inclusion	inclusion	NOUN
fnp-3671	10	90	size	size	NOUN
fnp-3671	10	91	in	in	ADP
fnp-3671	10	92	multiple	multiple	ADJ
fnp-3671	10	93	system	system	NOUN
fnp-3671	10	94	atrophy	atrophy	NOUN
fnp-3671	10	95	abstract	abstract	ADJ
fnp-3671	10	96	6	6	NUM
fnp-3671	10	97	:	:	PUNCT
fnp-3671	10	98	cognitive	cognitive	ADJ
fnp-3671	10	99	resilience	resilience	NOUN
fnp-3671	10	100	in	in	ADP
fnp-3671	10	101	individuals	individual	NOUN
fnp-3671	10	102	with	with	ADP
fnp-3671	10	103	severe	severe	ADJ
fnp-3671	10	104	alzheimer	alzheimer	PROPN
fnp-3671	10	105	’s	’s	PART
fnp-3671	10	106	disease	disease	NOUN
fnp-3671	10	107	neuropathology	neuropathology	NOUN
fnp-3671	10	108	abstract	abstract	ADJ
fnp-3671	10	109	7	7	NUM
fnp-3671	10	110	:	:	PUNCT
fnp-3671	10	111	linking	link	VERB
fnp-3671	10	112	iron	iron	NOUN
fnp-3671	10	113	homeostasis	homeostasis	NOUN
fnp-3671	10	114	to	to	ADP
fnp-3671	10	115	vulnerability	vulnerability	NOUN
fnp-3671	10	116	patterns	pattern	NOUN
fnp-3671	10	117	in	in	ADP
fnp-3671	10	118	progressive	progressive	ADJ
fnp-3671	10	119	supranuclear	supranuclear	ADJ
fnp-3671	10	120	palsy	palsy	ADJ
fnp-3671	10	121	abstract	abstract	ADJ
fnp-3671	10	122	8	8	NUM
fnp-3671	10	123	:	:	PUNCT
fnp-3671	10	124	friedreich	friedreich	NOUN
fnp-3671	10	125	cardiomyopathy	cardiomyopathy	ADJ
fnp-3671	10	126	is	be	AUX
fnp-3671	10	127	a	a	DET
fnp-3671	10	128	secondary	secondary	ADJ
fnp-3671	10	129	desminopathy	desminopathy	ADJ
fnp-3671	10	130	abstract	abstract	ADJ
fnp-3671	10	131	9	9	NUM
fnp-3671	10	132	:	:	PUNCT
fnp-3671	10	133	glial	glial	ADJ
fnp-3671	10	134	senescence	senescence	NOUN
fnp-3671	10	135	(	(	PUNCT
fnp-3671	10	136	not	not	PART
fnp-3671	10	137	tau	tau	PROPN
fnp-3671	10	138	)	)	PUNCT
fnp-3671	10	139	is	be	AUX
fnp-3671	10	140	the	the	DET
fnp-3671	10	141	driver	driver	NOUN
fnp-3671	10	142	of	of	ADP
fnp-3671	10	143	post	post	ADJ
fnp-3671	10	144	-	-	ADJ
fnp-3671	10	145	concussive	concussive	ADJ
fnp-3671	10	146	symptoms	symptom	NOUN
fnp-3671	10	147	abstract	abstract	ADJ
fnp-3671	10	148	10	10	NUM
fnp-3671	10	149	:	:	PUNCT
fnp-3671	10	150	hail	hail	NOUN
fnp-3671	10	151	to	to	PART
fnp-3671	10	152	astrogliosis	astrogliosis	VERB
fnp-3671	10	153	!	!	PUNCT
fnp-3671	11	1	the	the	DET
fnp-3671	11	2	unsung	unsung	ADJ
fnp-3671	11	3	hero	hero	NOUN
fnp-3671	11	4	of	of	ADP
fnp-3671	11	5	the	the	DET
fnp-3671	11	6	cns	cns	NOUN
fnp-3671	11	7	tissue	tissue	NOUN
fnp-3671	11	8	reaction	reaction	NOUN
fnp-3671	11	9	to	to	ADP
fnp-3671	11	10	the	the	DET
fnp-3671	11	11	spinal	spinal	PROPN
fnp-3671	11	12	cord	cord	NOUN
fnp-3671	11	13	injury	injury	NOUN
fnp-3671	11	14	abstract	abstract	ADJ
fnp-3671	11	15	11	11	NUM
fnp-3671	11	16	:	:	PUNCT
fnp-3671	11	17	ischemic	ischemic	ADJ
fnp-3671	11	18	-	-	PUNCT
fnp-3671	11	19	like	like	ADJ
fnp-3671	11	20	pathology	pathology	NOUN
fnp-3671	11	21	in	in	ADP
fnp-3671	11	22	aberrant	aberrant	ADJ
fnp-3671	11	23	white	white	ADJ
fnp-3671	11	24	matter	matter	NOUN
fnp-3671	11	25	tracts	tract	NOUN
fnp-3671	11	26	of	of	ADP
fnp-3671	11	27	fetal	fetal	ADJ
fnp-3671	11	28	holoprosencephaly	holoprosencephaly	NOUN
fnp-3671	11	29	:	:	PUNCT
fnp-3671	11	30	a	a	DET
fnp-3671	11	31	case	case	NOUN
fnp-3671	11	32	series	series	NOUN
fnp-3671	11	33	abstract	abstract	ADJ
fnp-3671	11	34	12	12	NUM
fnp-3671	11	35	:	:	PUNCT
fnp-3671	11	36	brain	brain	NOUN
fnp-3671	11	37	pathology	pathology	NOUN
fnp-3671	11	38	in	in	ADP
fnp-3671	11	39	patients	patient	NOUN
fnp-3671	11	40	with	with	ADP
fnp-3671	11	41	congenital	congenital	ADJ
fnp-3671	11	42	heart	heart	NOUN
fnp-3671	11	43	disease	disease	NOUN
fnp-3671	11	44	abstract	abstract	ADJ
fnp-3671	11	45	13	13	NUM
fnp-3671	11	46	:	:	PUNCT
fnp-3671	11	47	characterizing	characterize	VERB
fnp-3671	11	48	the	the	DET
fnp-3671	11	49	hippocampal	hippocampal	ADJ
fnp-3671	11	50	dentate	dentate	NOUN
fnp-3671	11	51	gyrus	gyrus	NOUN
fnp-3671	11	52	involvement	involvement	NOUN
fnp-3671	11	53	in	in	ADP
fnp-3671	11	54	temporal	temporal	ADJ
fnp-3671	11	55	lobe	lobe	NOUN
fnp-3671	11	56	epilepsy	epilepsy	NOUN
fnp-3671	11	57	abstract	abstract	ADJ
fnp-3671	11	58	14	14	NUM
fnp-3671	11	59	:	:	PUNCT
fnp-3671	11	60	deep	deep	ADJ
fnp-3671	11	61	learning	learning	NOUN
fnp-3671	11	62	approaches	approach	NOUN
fnp-3671	11	63	to	to	ADP
fnp-3671	11	64	deciphering	decipher	VERB
fnp-3671	11	65	intra	intra	ADJ
fnp-3671	11	66	-	-	ADJ
fnp-3671	11	67	tumoural	tumoural	ADJ
fnp-3671	11	68	heterogeneity	heterogeneity	NOUN
fnp-3671	11	69	in	in	ADP
fnp-3671	11	70	glioblastoma	glioblastoma	NOUN
fnp-3671	11	71	abstract	abstract	ADJ
fnp-3671	11	72	15	15	NUM
fnp-3671	11	73	:	:	PUNCT
fnp-3671	11	74	integrating	integrate	VERB
fnp-3671	11	75	morphologic	morphologic	ADJ
fnp-3671	11	76	and	and	CCONJ
fnp-3671	11	77	molecular	molecular	ADJ
fnp-3671	11	78	histopathological	histopathological	ADJ
fnp-3671	11	79	features	feature	NOUN
fnp-3671	11	80	through	through	ADP
fnp-3671	11	81	whole	whole	ADJ
fnp-3671	11	82	slide	slide	NOUN
fnp-3671	11	83	image	image	NOUN
fnp-3671	11	84	registration	registration	NOUN
fnp-3671	11	85	and	and	CCONJ
fnp-3671	11	86	deep	deep	ADJ
fnp-3671	11	87	learning	learning	NOUN
fnp-3671	11	88	abstract	abstract	ADJ
fnp-3671	11	89	16	16	NUM
fnp-3671	11	90	:	:	PUNCT
fnp-3671	11	91	neuropathology	neuropathology	NOUN
fnp-3671	11	92	of	of	ADP
fnp-3671	11	93	eight	eight	NUM
fnp-3671	11	94	cases	case	NOUN
fnp-3671	11	95	of	of	ADP
fnp-3671	11	96	the	the	DET
fnp-3671	11	97	new	new	ADJ
fnp-3671	11	98	brunswick	brunswick	PROPN
fnp-3671	11	99	cluster	cluster	NOUN
fnp-3671	11	100	of	of	ADP
fnp-3671	11	101	neurological	neurological	ADJ
fnp-3671	11	102	syndrome	syndrome	NOUN
fnp-3671	11	103	of	of	ADP
fnp-3671	11	104	unknown	unknown	ADJ
fnp-3671	11	105	cause	cause	NOUN
fnp-3671	11	106	(	(	PUNCT
fnp-3671	11	107	nsuc	nsuc	ADV
fnp-3671	11	108	)	)	PUNCT
fnp-3671	11	109	abstract	abstract	ADJ
fnp-3671	11	110	17	17	NUM
fnp-3671	11	111	:	:	PUNCT
fnp-3671	11	112	covid-19	covid-19	PROPN
fnp-3671	11	113	pandemic	pandemic	ADJ
fnp-3671	11	114	impact	impact	NOUN
fnp-3671	11	115	on	on	ADP
fnp-3671	11	116	surgical	surgical	ADJ
fnp-3671	11	117	neuropathology	neuropathology	NOUN
fnp-3671	11	118	services	service	NOUN
fnp-3671	11	119	at	at	ADP
fnp-3671	11	120	london	london	PROPN
fnp-3671	11	121	health	health	PROPN
fnp-3671	11	122	sciences	sciences	PROPN
fnp-3671	11	123	centre	centre	PROPN
fnp-3671	11	124	    	    	SPACE
fnp-3671	11	125	abstract	abstract	ADJ
fnp-3671	11	126	1	1	NUM
fnp-3671	11	127	free	free	ADJ
fnp-3671	11	128	neuropathol	neuropathol	NOUN
fnp-3671	11	129	2:29:4	2:29:4	NUM
fnp-3671	11	130	histologic	histologic	ADJ
fnp-3671	11	131	and	and	CCONJ
fnp-3671	11	132	clinical	clinical	ADJ
fnp-3671	11	133	spectrum	spectrum	NOUN
fnp-3671	11	134	of	of	ADP
fnp-3671	11	135	brain	brain	NOUN
fnp-3671	11	136	tumours	tumour	NOUN
fnp-3671	11	137	harbouring	harbour	VERB
fnp-3671	11	138	fgfr3	fgfr3	NOUN
fnp-3671	11	139	-	-	PUNCT
fnp-3671	11	140	tacc3	tacc3	PROPN
fnp-3671	11	141	fusions	fusion	NOUN
fnp-3671	11	142	francesca	francesca	PROPN
fnp-3671	11	143	gianno1	gianno1	PROPN
fnp-3671	11	144	,	,	PUNCT
fnp-3671	11	145	jennifer	jennifer	PROPN
fnp-3671	11	146	a.	a.	NOUN
fnp-3671	11	147	chan2	chan2	PROPN
fnp-3671	11	148	,	,	PUNCT
fnp-3671	11	149	phedias	phedia	VERB
fnp-3671	11	150	diamandis3,4	diamandis3,4	PROPN
fnp-3671	11	151	,	,	PUNCT
fnp-3671	11	152	john	john	PROPN
fnp-3671	11	153	a.	a.	PROPN
fnp-3671	11	154	maguire5	maguire5	PROPN
fnp-3671	11	155	,	,	PUNCT
fnp-3671	11	156	qi	qi	PROPN
fnp-3671	11	157	zhang6	zhang6	PROPN
fnp-3671	11	158	,	,	PUNCT
fnp-3671	11	159	cynthia	cynthia	PROPN
fnp-3671	11	160	hawkins1	hawkins1	PROPN
fnp-3671	11	161	,	,	PUNCT
fnp-3671	11	162	lili	lili	NOUN
fnp-3671	11	163	-	-	PUNCT
fnp-3671	11	164	naz	naz	PROPN
fnp-3671	11	165	hazrati1	hazrati1	NOUN
fnp-3671	11	166	1	1	NUM
fnp-3671	11	167	department	department	NOUN
fnp-3671	11	168	of	of	ADP
fnp-3671	11	169	laboratory	laboratory	NOUN
fnp-3671	11	170	medicine	medicine	NOUN
fnp-3671	11	171	and	and	CCONJ
fnp-3671	11	172	pathobiology	pathobiology	NOUN
fnp-3671	11	173	,	,	PUNCT
fnp-3671	11	174	university	university	PROPN
fnp-3671	11	175	of	of	ADP
fnp-3671	11	176	toronto	toronto	PROPN
fnp-3671	11	177	,	,	PUNCT
fnp-3671	11	178	toronto	toronto	PROPN
fnp-3671	11	179	,	,	PUNCT
fnp-3671	11	180	ontario	ontario	PROPN
fnp-3671	11	181	,	,	PUNCT
fnp-3671	11	182	canada	canada	PROPN
fnp-3671	11	183	;	;	PUNCT
fnp-3671	11	184	department	department	PROPN
fnp-3671	11	185	of	of	ADP
fnp-3671	11	186	pathology	pathology	PROPN
fnp-3671	11	187	,	,	PUNCT
fnp-3671	11	188	the	the	DET
fnp-3671	11	189	hospital	hospital	NOUN
fnp-3671	11	190	for	for	ADP
fnp-3671	11	191	sick	sick	ADJ
fnp-3671	11	192	children	child	NOUN
fnp-3671	11	193	,	,	PUNCT
fnp-3671	11	194	toronto	toronto	PROPN
fnp-3671	11	195	,	,	PUNCT
fnp-3671	11	196	ontario	ontario	PROPN
fnp-3671	11	197	,	,	PUNCT
fnp-3671	11	198	canada	canada	PROPN
fnp-3671	11	199	2	2	NUM
fnp-3671	11	200	university	university	PROPN
fnp-3671	11	201	of	of	ADP
fnp-3671	11	202	calgary	calgary	PROPN
fnp-3671	11	203	,	,	PUNCT
fnp-3671	11	204	calgary	calgary	PROPN
fnp-3671	11	205	,	,	PUNCT
fnp-3671	11	206	alberta	alberta	PROPN
fnp-3671	11	207	,	,	PUNCT
fnp-3671	11	208	canada	canada	PROPN
fnp-3671	11	209	3	3	NUM
fnp-3671	11	210	princess	princess	PROPN
fnp-3671	11	211	margaret	margaret	PROPN
fnp-3671	11	212	cancer	cancer	PROPN
fnp-3671	11	213	centre	centre	PROPN
fnp-3671	11	214	/	/	SYM
fnp-3671	11	215	laboratory	laboratory	NOUN
fnp-3671	11	216	medicine	medicine	NOUN
fnp-3671	11	217	program	program	NOUN
fnp-3671	11	218	,	,	PUNCT
fnp-3671	11	219	university	university	NOUN
fnp-3671	11	220	health	health	NOUN
fnp-3671	11	221	network	network	NOUN
fnp-3671	11	222	,	,	PUNCT
fnp-3671	11	223	toronto	toronto	PROPN
fnp-3671	11	224	,	,	PUNCT
fnp-3671	11	225	ontario	ontario	PROPN
fnp-3671	11	226	,	,	PUNCT
fnp-3671	11	227	canada	canada	PROPN
fnp-3671	11	228	4	4	NUM
fnp-3671	11	229	departments	department	NOUN
fnp-3671	11	230	of	of	ADP
fnp-3671	11	231	laboratory	laboratory	NOUN
fnp-3671	11	232	medicine	medicine	NOUN
fnp-3671	11	233	and	and	CCONJ
fnp-3671	11	234	pathobiology	pathobiology	NOUN
fnp-3671	11	235	and	and	CCONJ
fnp-3671	11	236	medical	medical	ADJ
fnp-3671	11	237	biophysics	biophysic	NOUN
fnp-3671	11	238	,	,	PUNCT
fnp-3671	11	239	university	university	PROPN
fnp-3671	11	240	of	of	ADP
fnp-3671	11	241	toronto	toronto	PROPN
fnp-3671	11	242	,	,	PUNCT
fnp-3671	11	243	toronto	toronto	PROPN
fnp-3671	11	244	,	,	PUNCT
fnp-3671	11	245	ontario	ontario	PROPN
fnp-3671	11	246	,	,	PUNCT
fnp-3671	11	247	canada	canada	PROPN
fnp-3671	11	248	5	5	NUM
fnp-3671	11	249	department	department	PROPN
fnp-3671	11	250	of	of	ADP
fnp-3671	11	251	pathology	pathology	PROPN
fnp-3671	11	252	&	&	CCONJ
fnp-3671	11	253	laboratory	laboratory	PROPN
fnp-3671	11	254	medicine	medicine	NOUN
fnp-3671	11	255	,	,	PUNCT
fnp-3671	11	256	costal	costal	ADJ
fnp-3671	11	257	health	health	NOUN
fnp-3671	11	258	-	-	PUNCT
fnp-3671	11	259	vancouver	vancouver	NOUN
fnp-3671	11	260	general	general	PROPN
fnp-3671	11	261	hospital	hospital	PROPN
fnp-3671	11	262	,	,	PUNCT
fnp-3671	11	263	canada	canada	PROPN
fnp-3671	11	264	6	6	NUM
fnp-3671	11	265	department	department	NOUN
fnp-3671	11	266	of	of	ADP
fnp-3671	11	267	pathology	pathology	PROPN
fnp-3671	11	268	,	,	PUNCT
fnp-3671	11	269	london	london	PROPN
fnp-3671	11	270	health	health	PROPN
fnp-3671	11	271	sciences	sciences	PROPN
fnp-3671	11	272	centre	centre	PROPN
fnp-3671	11	273	,	,	PUNCT
fnp-3671	11	274	london	london	PROPN
fnp-3671	11	275	,	,	PUNCT
fnp-3671	11	276	canada	canada	PROPN
fnp-3671	11	277	fibroblast	fibroblast	ADJ
fnp-3671	11	278	growth	growth	NOUN
fnp-3671	11	279	factor	factor	NOUN
fnp-3671	11	280	receptor	receptor	NOUN
fnp-3671	11	281	(	(	PUNCT
fnp-3671	11	282	fgfr	fgfr	ADJ
fnp-3671	11	283	)	)	PUNCT
fnp-3671	11	284	gene	gene	NOUN
fnp-3671	11	285	family	family	NOUN
fnp-3671	11	286	alterations	alteration	NOUN
fnp-3671	11	287	,	,	PUNCT
fnp-3671	11	288	including	include	VERB
fnp-3671	11	289	point	point	NOUN
fnp-3671	11	290	mutations	mutation	NOUN
fnp-3671	11	291	and	and	CCONJ
fnp-3671	11	292	fusions	fusion	NOUN
fnp-3671	11	293	,	,	PUNCT
fnp-3671	11	294	have	have	AUX
fnp-3671	11	295	been	be	AUX
fnp-3671	11	296	described	describe	VERB
fnp-3671	11	297	in	in	ADP
fnp-3671	11	298	brain	brain	NOUN
fnp-3671	11	299	tumours	tumour	NOUN
fnp-3671	11	300	as	as	ADP
fnp-3671	11	301	oncogenic	oncogenic	ADJ
fnp-3671	11	302	drivers	driver	NOUN
fnp-3671	11	303	(	(	PUNCT
fnp-3671	11	304	ng	ng	PROPN
fnp-3671	11	305	2013	2013	NUM
fnp-3671	11	306	;	;	PUNCT
fnp-3671	11	307	45(6	45(6	NUM
fnp-3671	11	308	):	):	PUNCT
fnp-3671	11	309	602–612	602–612	NUM
fnp-3671	11	310	)	)	PUNCT
fnp-3671	11	311	.	.	PUNCT
fnp-3671	12	1	fgfr3	fgfr3	NOUN
fnp-3671	12	2	-	-	PUNCT
fnp-3671	12	3	tacc3	tacc3	PROPN
fnp-3671	12	4	fusions	fusion	NOUN
fnp-3671	12	5	were	be	AUX
fnp-3671	12	6	initially	initially	ADV
fnp-3671	12	7	described	describe	VERB
fnp-3671	12	8	in	in	ADP
fnp-3671	12	9	idh	idh	PROPN
fnp-3671	12	10	wildtype	wildtype	NOUN
fnp-3671	12	11	glioblastomas	glioblastoma	NOUN
fnp-3671	12	12	(	(	PUNCT
fnp-3671	12	13	science	science	NOUN
fnp-3671	12	14	2012	2012	NUM
fnp-3671	12	15	;	;	PUNCT
fnp-3671	12	16	337:1231–1235	337:1231–1235	NUM
fnp-3671	12	17	)	)	PUNCT
fnp-3671	12	18	and	and	CCONJ
fnp-3671	12	19	are	be	AUX
fnp-3671	12	20	most	most	ADV
fnp-3671	12	21	frequently	frequently	ADV
fnp-3671	12	22	seen	see	VERB
fnp-3671	12	23	in	in	ADP
fnp-3671	12	24	morphologic	morphologic	ADJ
fnp-3671	12	25	or	or	CCONJ
fnp-3671	12	26	molecular	molecular	ADJ
fnp-3671	12	27	gbm	gbm	NOUN
fnp-3671	12	28	although	although	SCONJ
fnp-3671	12	29	occasional	occasional	ADJ
fnp-3671	12	30	who	who	PRON
fnp-3671	12	31	grade	grade	NOUN
fnp-3671	12	32	2	2	NUM
fnp-3671	12	33	astrocytomas	astrocytoma	NOUN
fnp-3671	12	34	may	may	AUX
fnp-3671	12	35	harbour	harbour	VERB
fnp-3671	12	36	this	this	DET
fnp-3671	12	37	alteration	alteration	NOUN
fnp-3671	12	38	.	.	PUNCT
fnp-3671	13	1	the	the	DET
fnp-3671	13	2	significance	significance	NOUN
fnp-3671	13	3	of	of	ADP
fnp-3671	13	4	this	this	DET
fnp-3671	13	5	alteration	alteration	NOUN
fnp-3671	13	6	as	as	ADP
fnp-3671	13	7	a	a	DET
fnp-3671	13	8	single	single	ADJ
fnp-3671	13	9	driver	driver	NOUN
fnp-3671	13	10	in	in	ADP
fnp-3671	13	11	low	low	ADJ
fnp-3671	13	12	-	-	PUNCT
fnp-3671	13	13	grade	grade	NOUN
fnp-3671	13	14	glioma	glioma	NOUN
fnp-3671	13	15	is	be	AUX
fnp-3671	13	16	unclear	unclear	ADJ
fnp-3671	13	17	.	.	PUNCT
fnp-3671	14	1	in	in	ADP
fnp-3671	14	2	order	order	NOUN
fnp-3671	14	3	to	to	PART
fnp-3671	14	4	better	well	ADV
fnp-3671	14	5	understand	understand	VERB
fnp-3671	14	6	the	the	DET
fnp-3671	14	7	clinical	clinical	ADJ
fnp-3671	14	8	implications	implication	NOUN
fnp-3671	14	9	of	of	ADP
fnp-3671	14	10	finding	find	VERB
fnp-3671	14	11	this	this	DET
fnp-3671	14	12	alteration	alteration	NOUN
fnp-3671	14	13	,	,	PUNCT
fnp-3671	14	14	a	a	DET
fnp-3671	14	15	series	series	NOUN
fnp-3671	14	16	of	of	ADP
fnp-3671	14	17	low	low	ADJ
fnp-3671	14	18	-	-	PUNCT
fnp-3671	14	19	grade	grade	NOUN
fnp-3671	14	20	gliomas	glioma	NOUN
fnp-3671	14	21	underwent	undergo	VERB
fnp-3671	14	22	molecular	molecular	ADJ
fnp-3671	14	23	testing	testing	NOUN
fnp-3671	14	24	at	at	ADP
fnp-3671	14	25	sickkids	sickkid	NOUN
fnp-3671	14	26	.	.	PUNCT
fnp-3671	15	1	the	the	DET
fnp-3671	15	2	series	series	NOUN
fnp-3671	15	3	includes	include	VERB
fnp-3671	15	4	six	six	NUM
fnp-3671	15	5	samples	sample	NOUN
fnp-3671	15	6	of	of	ADP
fnp-3671	15	7	diffuse	diffuse	ADJ
fnp-3671	15	8	low	low	ADJ
fnp-3671	15	9	-	-	PUNCT
fnp-3671	15	10	grade	grade	NOUN
fnp-3671	15	11	gliomas	glioma	NOUN
fnp-3671	15	12	,	,	PUNCT
fnp-3671	15	13	with	with	ADP
fnp-3671	15	14	a	a	DET
fnp-3671	15	15	mean	mean	ADJ
fnp-3671	15	16	age	age	NOUN
fnp-3671	15	17	of	of	ADP
fnp-3671	15	18	24.8	24.8	NUM
fnp-3671	15	19	years	year	NOUN
fnp-3671	15	20	(	(	PUNCT
fnp-3671	15	21	range	range	NOUN
fnp-3671	15	22	1	1	NUM
fnp-3671	15	23	to	to	PART
fnp-3671	15	24	44	44	NUM
fnp-3671	15	25	years	year	NOUN
fnp-3671	15	26	)	)	PUNCT
fnp-3671	15	27	,	,	PUNCT
fnp-3671	15	28	three	three	NUM
fnp-3671	15	29	males	male	NOUN
fnp-3671	15	30	and	and	CCONJ
fnp-3671	15	31	three	three	NUM
fnp-3671	15	32	females	female	NOUN
fnp-3671	15	33	.	.	PUNCT
fnp-3671	16	1	five	five	NUM
fnp-3671	16	2	out	out	ADP
fnp-3671	16	3	of	of	ADP
fnp-3671	16	4	six	six	NUM
fnp-3671	16	5	tumours	tumour	NOUN
fnp-3671	16	6	are	be	AUX
fnp-3671	16	7	localized	localize	VERB
fnp-3671	16	8	in	in	ADP
fnp-3671	16	9	the	the	DET
fnp-3671	16	10	supratentorial	supratentorial	ADJ
fnp-3671	16	11	region	region	NOUN
fnp-3671	16	12	,	,	PUNCT
fnp-3671	16	13	and	and	CCONJ
fnp-3671	16	14	one	one	NUM
fnp-3671	16	15	in	in	ADP
fnp-3671	16	16	the	the	DET
fnp-3671	16	17	spinal	spinal	NOUN
fnp-3671	16	18	cord	cord	NOUN
fnp-3671	16	19	.	.	PUNCT
fnp-3671	17	1	three	three	NUM
fnp-3671	17	2	patients	patient	NOUN
fnp-3671	17	3	presented	present	VERB
fnp-3671	17	4	with	with	ADP
fnp-3671	17	5	seizures	seizure	NOUN
fnp-3671	17	6	,	,	PUNCT
fnp-3671	17	7	one	one	NUM
fnp-3671	17	8	was	be	AUX
fnp-3671	17	9	asymptomatic	asymptomatic	ADJ
fnp-3671	17	10	.	.	PUNCT
fnp-3671	18	1	morphologic	morphologic	ADJ
fnp-3671	18	2	appearance	appearance	NOUN
fnp-3671	18	3	showed	show	VERB
fnp-3671	18	4	different	different	ADJ
fnp-3671	18	5	aspects	aspect	NOUN
fnp-3671	18	6	,	,	PUNCT
fnp-3671	18	7	from	from	ADP
fnp-3671	18	8	cells	cell	NOUN
fnp-3671	18	9	with	with	ADP
fnp-3671	18	10	oligo	oligo	NOUN
fnp-3671	18	11	-	-	PUNCT
fnp-3671	18	12	like	like	ADJ
fnp-3671	18	13	features	feature	NOUN
fnp-3671	18	14	in	in	ADP
fnp-3671	18	15	a	a	DET
fnp-3671	18	16	neuropil	neuropil	NOUN
fnp-3671	18	17	-	-	PUNCT
fnp-3671	18	18	rich	rich	ADJ
fnp-3671	18	19	stroma	stroma	NOUN
fnp-3671	18	20	to	to	PART
fnp-3671	18	21	spindle	spindle	VERB
fnp-3671	18	22	cells	cell	NOUN
fnp-3671	18	23	with	with	ADP
fnp-3671	18	24	fibrillary	fibrillary	ADJ
fnp-3671	18	25	cytoplasm	cytoplasm	NOUN
fnp-3671	18	26	in	in	ADP
fnp-3671	18	27	a	a	DET
fnp-3671	18	28	loose	loose	ADJ
fnp-3671	18	29	microcystic	microcystic	ADJ
fnp-3671	18	30	background	background	NOUN
fnp-3671	18	31	.	.	PUNCT
fnp-3671	19	1	single	single	ADJ
fnp-3671	19	2	nucleotide	nucleotide	ADJ
fnp-3671	19	3	polymorphism	polymorphism	NOUN
fnp-3671	19	4	(	(	PUNCT
fnp-3671	19	5	snp	snp	ADJ
fnp-3671	19	6	)	)	PUNCT
fnp-3671	19	7	array	array	NOUN
fnp-3671	19	8	was	be	AUX
fnp-3671	19	9	performed	perform	VERB
fnp-3671	19	10	on	on	ADP
fnp-3671	19	11	two	two	NUM
fnp-3671	19	12	samples	sample	NOUN
fnp-3671	19	13	and	and	CCONJ
fnp-3671	19	14	one	one	NUM
fnp-3671	19	15	of	of	ADP
fnp-3671	19	16	them	they	PRON
fnp-3671	19	17	shows	show	VERB
fnp-3671	19	18	the	the	DET
fnp-3671	19	19	gain	gain	NOUN
fnp-3671	19	20	of	of	ADP
fnp-3671	19	21	chromosome	chromosome	NOUN
fnp-3671	19	22	7	7	NUM
fnp-3671	19	23	and	and	CCONJ
fnp-3671	19	24	loss	loss	NOUN
fnp-3671	19	25	of	of	ADP
fnp-3671	19	26	chromosome	chromosome	NOUN
fnp-3671	19	27	10	10	NUM
fnp-3671	19	28	,	,	PUNCT
fnp-3671	19	29	indicating	indicate	VERB
fnp-3671	19	30	a	a	DET
fnp-3671	19	31	molecular	molecular	ADJ
fnp-3671	19	32	profile	profile	NOUN
fnp-3671	19	33	of	of	ADP
fnp-3671	19	34	high	high	ADJ
fnp-3671	19	35	grade	grade	NOUN
fnp-3671	19	36	glioma	glioma	NOUN
fnp-3671	19	37	.	.	PUNCT
fnp-3671	20	1	follow	follow	VERB
fnp-3671	20	2	-	-	PUNCT
fnp-3671	20	3	up	up	NOUN
fnp-3671	20	4	was	be	AUX
fnp-3671	20	5	available	available	ADJ
fnp-3671	20	6	for	for	ADP
fnp-3671	20	7	four	four	NUM
fnp-3671	20	8	patients	patient	NOUN
fnp-3671	20	9	,	,	PUNCT
fnp-3671	20	10	all	all	PRON
fnp-3671	20	11	are	be	AUX
fnp-3671	20	12	alive	alive	ADJ
fnp-3671	20	13	without	without	ADP
fnp-3671	20	14	progressive	progressive	ADJ
fnp-3671	20	15	disease	disease	NOUN
fnp-3671	20	16	with	with	ADP
fnp-3671	20	17	follow	follow	NOUN
fnp-3671	20	18	-	-	PUNCT
fnp-3671	20	19	up	up	NOUN
fnp-3671	20	20	ranging	range	VERB
fnp-3671	20	21	from	from	ADP
fnp-3671	20	22	six	six	NUM
fnp-3671	20	23	months	month	NOUN
fnp-3671	20	24	to	to	ADP
fnp-3671	20	25	two	two	NUM
fnp-3671	20	26	years	year	NOUN
fnp-3671	20	27	.	.	PUNCT
fnp-3671	21	1	longer	long	ADV
fnp-3671	21	2	follow	follow	VERB
fnp-3671	21	3	-	-	PUNCT
fnp-3671	21	4	up	up	NOUN
fnp-3671	21	5	will	will	AUX
fnp-3671	21	6	be	be	AUX
fnp-3671	21	7	required	require	VERB
fnp-3671	21	8	to	to	PART
fnp-3671	21	9	determine	determine	VERB
fnp-3671	21	10	the	the	DET
fnp-3671	21	11	significance	significance	NOUN
fnp-3671	21	12	of	of	ADP
fnp-3671	21	13	this	this	DET
fnp-3671	21	14	alteration	alteration	NOUN
fnp-3671	21	15	in	in	ADP
fnp-3671	21	16	low	low	ADJ
fnp-3671	21	17	grade	grade	NOUN
fnp-3671	21	18	glioma	glioma	NOUN
fnp-3671	21	19	.	.	PUNCT
fnp-3671	21	20	  	  	SPACE
fnp-3671	22	1	abstract	abstract	ADJ
fnp-3671	22	2	2	2	NUM
fnp-3671	22	3	free	free	ADJ
fnp-3671	22	4	neuropathol	neuropathol	NOUN
fnp-3671	22	5	2:29:5	2:29:5	NUM
fnp-3671	22	6	ganglion	ganglion	NOUN
fnp-3671	22	7	cell	cell	NOUN
fnp-3671	22	8	maturational	maturational	ADJ
fnp-3671	22	9	markers	marker	NOUN
fnp-3671	22	10	in	in	ADP
fnp-3671	22	11	peripheral	peripheral	ADJ
fnp-3671	22	12	neuroblastic	neuroblastic	ADJ
fnp-3671	22	13	tumours	tumour	NOUN
fnp-3671	22	14	of	of	ADP
fnp-3671	22	15	children	children	PROPN
fnp-3671	22	16	harvey	harvey	PROPN
fnp-3671	22	17	b.	b.	PROPN
fnp-3671	22	18	sarnat1	sarnat1	PROPN
fnp-3671	22	19	1	1	NUM
fnp-3671	22	20	university	university	PROPN
fnp-3671	22	21	of	of	ADP
fnp-3671	22	22	calgary	calgary	PROPN
fnp-3671	22	23	&	&	CCONJ
fnp-3671	22	24	alberta	alberta	PROPN
fnp-3671	22	25	children	children	PROPN
fnp-3671	22	26	's	's	PART
fnp-3671	22	27	hospital	hospital	NOUN
fnp-3671	22	28	,	,	PUNCT
fnp-3671	22	29	calgary	calgary	PROPN
fnp-3671	22	30	,	,	PUNCT
fnp-3671	22	31	alberta	alberta	PROPN
fnp-3671	22	32	,	,	PUNCT
fnp-3671	22	33	canada	canada	PROPN
fnp-3671	22	34	peripheral	peripheral	ADJ
fnp-3671	22	35	neuroblastic	neuroblastic	ADJ
fnp-3671	22	36	tumours	tumour	NOUN
fnp-3671	22	37	of	of	ADP
fnp-3671	22	38	neural	neural	ADJ
fnp-3671	22	39	crest	crest	PROPN
fnp-3671	22	40	origin	origin	NOUN
fnp-3671	22	41	are	be	AUX
fnp-3671	22	42	the	the	DET
fnp-3671	22	43	most	most	ADV
fnp-3671	22	44	frequent	frequent	ADJ
fnp-3671	22	45	solid	solid	ADJ
fnp-3671	22	46	neoplasms	neoplasm	NOUN
fnp-3671	22	47	outside	outside	ADP
fnp-3671	22	48	the	the	DET
fnp-3671	22	49	cns	cns	NOUN
fnp-3671	22	50	in	in	ADP
fnp-3671	22	51	children	child	NOUN
fnp-3671	22	52	.	.	PUNCT
fnp-3671	23	1	neuroblastoma	neuroblastoma	ADJ
fnp-3671	23	2	/	/	SYM
fnp-3671	23	3	ganglioneuroblastoma	ganglioneuroblastoma	NOUN
fnp-3671	23	4	have	have	VERB
fnp-3671	23	5	a	a	DET
fnp-3671	23	6	natural	natural	ADJ
fnp-3671	23	7	evolution	evolution	NOUN
fnp-3671	23	8	of	of	ADP
fnp-3671	23	9	histological	histological	ADJ
fnp-3671	23	10	differentiation	differentiation	NOUN
fnp-3671	23	11	over	over	ADP
fnp-3671	23	12	time	time	NOUN
fnp-3671	23	13	.	.	PUNCT
fnp-3671	24	1	together	together	ADV
fnp-3671	24	2	with	with	ADP
fnp-3671	24	3	mitosis	mitosis	NOUN
fnp-3671	24	4	-	-	PUNCT
fnp-3671	24	5	karyorrhexis	karyorrhexis	ADJ
fnp-3671	24	6	index	index	NOUN
fnp-3671	24	7	and	and	CCONJ
fnp-3671	24	8	patient	patient	ADJ
fnp-3671	24	9	age	age	NOUN
fnp-3671	24	10	(	(	PUNCT
fnp-3671	24	11	international	international	ADJ
fnp-3671	24	12	neuroblastoma	neuroblastoma	ADJ
fnp-3671	24	13	pathology	pathology	NOUN
fnp-3671	24	14	classification	classification	NOUN
fnp-3671	24	15	criteria	criterion	NOUN
fnp-3671	24	16	)	)	PUNCT
fnp-3671	24	17	,	,	PUNCT
fnp-3671	24	18	ganglion	ganglion	NOUN
fnp-3671	24	19	cell	cell	NOUN
fnp-3671	24	20	maturation	maturation	NOUN
fnp-3671	24	21	determines	determine	VERB
fnp-3671	24	22	grading	grade	VERB
fnp-3671	24	23	and	and	CCONJ
fnp-3671	24	24	prognosis	prognosis	NOUN
fnp-3671	24	25	.	.	PUNCT
fnp-3671	25	1	maturation	maturation	NOUN
fnp-3671	25	2	presently	presently	ADV
fnp-3671	25	3	is	be	AUX
fnp-3671	25	4	assessed	assess	VERB
fnp-3671	25	5	only	only	ADV
fnp-3671	25	6	by	by	ADP
fnp-3671	25	7	h&e	h&e	PROPN
fnp-3671	25	8	histology	histology	NOUN
fnp-3671	25	9	.	.	PUNCT
fnp-3671	26	1	methods	method	NOUN
fnp-3671	26	2	:	:	PUNCT
fnp-3671	26	3	immunocytochemical	immunocytochemical	ADJ
fnp-3671	26	4	markers	marker	NOUN
fnp-3671	26	5	of	of	ADP
fnp-3671	26	6	neuroblast	neuroblast	ADJ
fnp-3671	26	7	maturation	maturation	NOUN
fnp-3671	26	8	in	in	ADP
fnp-3671	26	9	fetal	fetal	ADJ
fnp-3671	26	10	cns	cns	NOUN
fnp-3671	26	11	were	be	AUX
fnp-3671	26	12	applied	apply	VERB
fnp-3671	26	13	to	to	ADP
fnp-3671	26	14	peripheral	peripheral	ADJ
fnp-3671	26	15	neuroblastic	neuroblastic	ADJ
fnp-3671	26	16	tumours	tumour	NOUN
fnp-3671	26	17	arising	arise	VERB
fnp-3671	26	18	in	in	ADP
fnp-3671	26	19	adrenal	adrenal	ADJ
fnp-3671	26	20	medulla	medulla	NOUN
fnp-3671	26	21	or	or	CCONJ
fnp-3671	26	22	sympathetic	sympathetic	ADJ
fnp-3671	26	23	chain	chain	NOUN
fnp-3671	26	24	.	.	PUNCT
fnp-3671	27	1	resected	resect	VERB
fnp-3671	27	2	tumours	tumour	NOUN
fnp-3671	27	3	of	of	ADP
fnp-3671	27	4	4	4	NUM
fnp-3671	27	5	toddlers	toddler	NOUN
fnp-3671	27	6	were	be	AUX
fnp-3671	27	7	examined	examine	VERB
fnp-3671	27	8	using	use	VERB
fnp-3671	27	9	antibodies	antibody	NOUN
fnp-3671	27	10	demonstrating	demonstrate	VERB
fnp-3671	27	11	neuronal	neuronal	ADJ
fnp-3671	27	12	identity	identity	NOUN
fnp-3671	27	13	and	and	CCONJ
fnp-3671	27	14	maturation	maturation	NOUN
fnp-3671	27	15	:	:	PUNCT
fnp-3671	27	16	map2	map2	NOUN
fnp-3671	27	17	;	;	PUNCT
fnp-3671	27	18	synaptophysin	synaptophysin	NOUN
fnp-3671	27	19	;	;	PUNCT
fnp-3671	27	20	chromogranin	chromogranin	NOUN
fnp-3671	27	21	-	-	PUNCT
fnp-3671	27	22	a	a	NOUN
fnp-3671	27	23	;	;	PUNCT
fnp-3671	27	24	neun	neun	NOUN
fnp-3671	27	25	;	;	PUNCT
fnp-3671	27	26	keratan	keratan	ADJ
fnp-3671	27	27	sulfate	sulfate	NOUN
fnp-3671	27	28	(	(	PUNCT
fnp-3671	27	29	ks	ks	NOUN
fnp-3671	27	30	)	)	PUNCT
fnp-3671	27	31	;	;	PUNCT
fnp-3671	27	32	glutamate	glutamate	VERB
fnp-3671	27	33	receptor	receptor	NOUN
fnp-3671	27	34	antibody	antibody	NOUN
fnp-3671	27	35	(	(	PUNCT
fnp-3671	27	36	glur2	glur2	NOUN
fnp-3671	27	37	)	)	PUNCT
fnp-3671	27	38	.	.	PUNCT
fnp-3671	28	1	others	other	NOUN
fnp-3671	28	2	:	:	PUNCT
fnp-3671	29	1	ki67	ki67	PROPN
fnp-3671	29	2	;	;	PUNCT
fnp-3671	29	3	s-100β	s-100β	ADJ
fnp-3671	29	4	protein	protein	NOUN
fnp-3671	29	5	;	;	PUNCT
fnp-3671	29	6	vimentin	vimentin	X
fnp-3671	29	7	;	;	PUNCT
fnp-3671	29	8	nestin	nestin	X
fnp-3671	29	9	;	;	PUNCT
fnp-3671	29	10	α	α	X
fnp-3671	29	11	-	-	PUNCT
fnp-3671	29	12	b	b	NOUN
fnp-3671	29	13	-	-	PUNCT
fnp-3671	29	14	crystallin	crystallin	NOUN
fnp-3671	29	15	;	;	PUNCT
fnp-3671	29	16	neuroblastoma	neuroblastoma	ADJ
fnp-3671	29	17	marker	marker	NOUN
fnp-3671	29	18	phox2b	phox2b	NOUN
fnp-3671	29	19	.	.	PUNCT
fnp-3671	30	1	results	result	NOUN
fnp-3671	30	2	:	:	PUNCT
fnp-3671	30	3	degrees	degree	NOUN
fnp-3671	30	4	of	of	ADP
fnp-3671	30	5	neuroblastic	neuroblastic	ADJ
fnp-3671	30	6	maturation	maturation	NOUN
fnp-3671	30	7	were	be	AUX
fnp-3671	30	8	demonstrated	demonstrate	VERB
fnp-3671	30	9	by	by	ADP
fnp-3671	30	10	map2	map2	PROPN
fnp-3671	30	11	,	,	PUNCT
fnp-3671	30	12	chromogranin	chromogranin	NOUN
fnp-3671	30	13	,	,	PUNCT
fnp-3671	30	14	synaptophysin	synaptophysin	NOUN
fnp-3671	30	15	,	,	PUNCT
fnp-3671	30	16	ks	ks	PROPN
fnp-3671	30	17	and	and	CCONJ
fnp-3671	30	18	glur2	glur2	PROPN
fnp-3671	30	19	;	;	PUNCT
fnp-3671	30	20	neun	neun	NOUN
fnp-3671	30	21	was	be	AUX
fnp-3671	30	22	negative	negative	ADJ
fnp-3671	30	23	consistent	consistent	ADJ
fnp-3671	30	24	with	with	ADP
fnp-3671	30	25	sympathetic	sympathetic	ADJ
fnp-3671	30	26	neural	neural	ADJ
fnp-3671	30	27	crest	crest	NOUN
fnp-3671	30	28	lineage	lineage	NOUN
fnp-3671	30	29	.	.	PUNCT
fnp-3671	31	1	ks	k	NOUN
fnp-3671	31	2	was	be	AUX
fnp-3671	31	3	sparsely	sparsely	ADV
fnp-3671	31	4	distributed	distribute	VERB
fnp-3671	31	5	within	within	ADP
fnp-3671	31	6	the	the	DET
fnp-3671	31	7	tumours	tumours	NOUN
fnp-3671	31	8	adherent	adherent	NOUN
fnp-3671	31	9	to	to	ADP
fnp-3671	31	10	somata	somata	ADJ
fnp-3671	31	11	and	and	CCONJ
fnp-3671	31	12	proximal	proximal	ADJ
fnp-3671	31	13	neuritic	neuritic	ADJ
fnp-3671	31	14	trunks	trunk	NOUN
fnp-3671	31	15	.	.	PUNCT
fnp-3671	32	1	phox2b	phox2b	NOUN
fnp-3671	32	2	did	do	AUX
fnp-3671	32	3	not	not	PART
fnp-3671	32	4	distinguish	distinguish	VERB
fnp-3671	32	5	maturational	maturational	ADJ
fnp-3671	32	6	stages	stage	NOUN
fnp-3671	32	7	.	.	PUNCT
fnp-3671	33	1	ki67	ki67	PROPN
fnp-3671	33	2	was	be	AUX
fnp-3671	33	3	expressed	express	VERB
fnp-3671	33	4	in	in	ADP
fnp-3671	33	5	scattered	scatter	VERB
fnp-3671	33	6	primitive	primitive	ADJ
fnp-3671	33	7	cells	cell	NOUN
fnp-3671	33	8	that	that	PRON
fnp-3671	33	9	also	also	ADV
fnp-3671	33	10	expressed	express	VERB
fnp-3671	33	11	vimentin	vimentin	NOUN
fnp-3671	33	12	and	and	CCONJ
fnp-3671	33	13	nestin	nestin	NOUN
fnp-3671	33	14	,	,	PUNCT
fnp-3671	33	15	but	but	CCONJ
fnp-3671	33	16	not	not	PART
fnp-3671	33	17	in	in	ADP
fnp-3671	33	18	differentiated	differentiated	ADJ
fnp-3671	33	19	neoplastic	neoplastic	ADJ
fnp-3671	33	20	neurons	neuron	NOUN
fnp-3671	33	21	.	.	PUNCT
fnp-3671	34	1	s-100β	s-100β	ADJ
fnp-3671	34	2	protein	protein	NOUN
fnp-3671	34	3	and	and	CCONJ
fnp-3671	34	4	α	α	NOUN
fnp-3671	34	5	-	-	PUNCT
fnp-3671	34	6	b	b	NOUN
fnp-3671	34	7	-	-	PUNCT
fnp-3671	34	8	crystallin	crystallin	NOUN
fnp-3671	34	9	labeled	label	VERB
fnp-3671	34	10	schwann	schwann	PROPN
fnp-3671	34	11	cells	cell	NOUN
fnp-3671	34	12	,	,	PUNCT
fnp-3671	34	13	especially	especially	ADV
fnp-3671	34	14	schwannian	schwannian	ADJ
fnp-3671	34	15	ganglioneuroma	ganglioneuroma	NOUN
fnp-3671	34	16	.	.	PUNCT
fnp-3671	35	1	conclusions	conclusion	NOUN
fnp-3671	35	2	:	:	PUNCT
fnp-3671	35	3	immunocytochemical	immunocytochemical	ADJ
fnp-3671	35	4	markers	marker	NOUN
fnp-3671	35	5	of	of	ADP
fnp-3671	35	6	neuroblast	neuroblast	ADJ
fnp-3671	35	7	maturation	maturation	NOUN
fnp-3671	35	8	in	in	ADP
fnp-3671	35	9	fetal	fetal	ADJ
fnp-3671	35	10	brain	brain	NOUN
fnp-3671	35	11	also	also	ADV
fnp-3671	35	12	are	be	AUX
fnp-3671	35	13	useful	useful	ADJ
fnp-3671	35	14	in	in	ADP
fnp-3671	35	15	peripheral	peripheral	ADJ
fnp-3671	35	16	neuroblastic	neuroblastic	ADJ
fnp-3671	35	17	tumours	tumour	NOUN
fnp-3671	35	18	,	,	PUNCT
fnp-3671	35	19	providing	provide	VERB
fnp-3671	35	20	greater	great	ADJ
fnp-3671	35	21	precision	precision	NOUN
fnp-3671	35	22	than	than	ADP
fnp-3671	35	23	histology	histology	NOUN
fnp-3671	35	24	alone	alone	ADV
fnp-3671	35	25	.	.	PUNCT
fnp-3671	36	1	the	the	DET
fnp-3671	36	2	most	most	ADV
fnp-3671	36	3	practical	practical	ADJ
fnp-3671	36	4	are	be	AUX
fnp-3671	36	5	map2	map2	ADJ
fnp-3671	36	6	and	and	CCONJ
fnp-3671	36	7	synaptophysin	synaptophysin	NOUN
fnp-3671	36	8	.	.	PUNCT
fnp-3671	37	1	prognosis	prognosis	NOUN
fnp-3671	37	2	and	and	CCONJ
fnp-3671	37	3	choice	choice	NOUN
fnp-3671	37	4	of	of	ADP
fnp-3671	37	5	treatment	treatment	NOUN
fnp-3671	37	6	including	include	VERB
fnp-3671	37	7	chemotherapy	chemotherapy	NOUN
fnp-3671	37	8	might	might	AUX
fnp-3671	37	9	be	be	AUX
fnp-3671	37	10	influenced	influence	VERB
fnp-3671	37	11	.	.	PUNCT
fnp-3671	37	12	  	  	SPACE
fnp-3671	38	1	abstract	abstract	ADJ
fnp-3671	38	2	3	3	NUM
fnp-3671	38	3	free	free	ADJ
fnp-3671	38	4	neuropathol	neuropathol	NOUN
fnp-3671	38	5	2:29:6	2:29:6	NUM
fnp-3671	38	6	long	long	ADJ
fnp-3671	38	7	term	term	NOUN
fnp-3671	38	8	disease	disease	NOUN
fnp-3671	38	9	-	-	PUNCT
fnp-3671	38	10	free	free	ADJ
fnp-3671	38	11	survival	survival	NOUN
fnp-3671	38	12	after	after	ADP
fnp-3671	38	13	surgical	surgical	ADJ
fnp-3671	38	14	resection	resection	NOUN
fnp-3671	38	15	only	only	ADV
fnp-3671	38	16	:	:	PUNCT
fnp-3671	38	17	malignant	malignant	ADJ
fnp-3671	38	18	idh	idh	NOUN
fnp-3671	38	19	-	-	PUNCT
fnp-3671	38	20	mutated	mutate	VERB
fnp-3671	38	21	astrocytoma	astrocytoma	NOUN
fnp-3671	38	22	versus	versus	ADP
fnp-3671	38	23	ganglioglioma	ganglioglioma	PROPN
fnp-3671	38	24	roland	roland	PROPN
fnp-3671	38	25	n.	n.	PROPN
fnp-3671	38	26	auer1,5	auer1,5	PROPN
fnp-3671	38	27	,	,	PUNCT
fnp-3671	38	28	egiroh	egiroh	NOUN
fnp-3671	38	29	omene2	omene2	NOUN
fnp-3671	38	30	,	,	PUNCT
fnp-3671	38	31	sarah	sarah	PROPN
fnp-3671	38	32	e.	e.	PROPN
fnp-3671	38	33	edwards1	edwards1	PROPN
fnp-3671	38	34	,	,	PUNCT
fnp-3671	38	35	kotoo	kotoo	NOUN
fnp-3671	38	36	meguro1	meguro1	PROPN
fnp-3671	38	37	,	,	PUNCT
fnp-3671	38	38	daryl	daryl	PROPN
fnp-3671	38	39	r.	r.	PROPN
fnp-3671	38	40	fourney1	fourney1	PROPN
fnp-3671	38	41	,	,	PUNCT
fnp-3671	38	42	jose	jose	PROPN
fnp-3671	38	43	f.	f.	PROPN
fnp-3671	38	44	tellez	tellez	PROPN
fnp-3671	38	45	-	-	PUNCT
fnp-3671	38	46	zenteno2	zenteno2	PROPN
fnp-3671	38	47	,	,	PUNCT
fnp-3671	38	48	gary	gary	PROPN
fnp-3671	38	49	r.	r.	PROPN
fnp-3671	38	50	w.	w.	PROPN
fnp-3671	38	51	hunter2	hunter2	PROPN
fnp-3671	38	52	,	,	PUNCT
fnp-3671	38	53	kyle	kyle	PROPN
fnp-3671	38	54	moulton3	moulton3	PROPN
fnp-3671	38	55	,	,	PUNCT
fnp-3671	38	56	vijayananda	vijayananda	ADV
fnp-3671	38	57	kundapur4	kundapur4	PROPN
fnp-3671	38	58	1	1	NUM
fnp-3671	38	59	department	department	NOUN
fnp-3671	38	60	of	of	ADP
fnp-3671	38	61	surgery	surgery	NOUN
fnp-3671	38	62	(	(	PUNCT
fnp-3671	38	63	neurosurgery	neurosurgery	NOUN
fnp-3671	38	64	)	)	PUNCT
fnp-3671	38	65	,	,	PUNCT
fnp-3671	38	66	university	university	NOUN
fnp-3671	38	67	of	of	ADP
fnp-3671	38	68	saskatchewan	saskatchewan	PROPN
fnp-3671	38	69	,	,	PUNCT
fnp-3671	38	70	saskatoon	saskatoon	PROPN
fnp-3671	38	71	,	,	PUNCT
fnp-3671	38	72	saskatchewan	saskatchewan	PROPN
fnp-3671	38	73	,	,	PUNCT
fnp-3671	38	74	canada	canada	PROPN
fnp-3671	38	75	2	2	NUM
fnp-3671	38	76	department	department	NOUN
fnp-3671	38	77	of	of	ADP
fnp-3671	38	78	neurology	neurology	NOUN
fnp-3671	38	79	,	,	PUNCT
fnp-3671	38	80	university	university	PROPN
fnp-3671	38	81	of	of	ADP
fnp-3671	38	82	saskatchewan	saskatchewan	PROPN
fnp-3671	38	83	,	,	PUNCT
fnp-3671	38	84	saskatoon	saskatoon	PROPN
fnp-3671	38	85	,	,	PUNCT
fnp-3671	38	86	saskatchewan	saskatchewan	PROPN
fnp-3671	38	87	,	,	PUNCT
fnp-3671	38	88	canada	canada	PROPN
fnp-3671	38	89	3	3	NUM
fnp-3671	38	90	department	department	PROPN
fnp-3671	38	91	of	of	ADP
fnp-3671	38	92	radiology	radiology	NOUN
fnp-3671	38	93	,	,	PUNCT
fnp-3671	38	94	university	university	PROPN
fnp-3671	38	95	of	of	ADP
fnp-3671	38	96	saskatchewan	saskatchewan	PROPN
fnp-3671	38	97	,	,	PUNCT
fnp-3671	38	98	saskatoon	saskatoon	PROPN
fnp-3671	38	99	,	,	PUNCT
fnp-3671	38	100	saskatchewan	saskatchewan	PROPN
fnp-3671	38	101	,	,	PUNCT
fnp-3671	38	102	canada	canada	PROPN
fnp-3671	38	103	4	4	NUM
fnp-3671	38	104	department	department	NOUN
fnp-3671	38	105	of	of	ADP
fnp-3671	38	106	oncology	oncology	NOUN
fnp-3671	38	107	,	,	PUNCT
fnp-3671	38	108	university	university	PROPN
fnp-3671	38	109	of	of	ADP
fnp-3671	38	110	saskatchewan	saskatchewan	PROPN
fnp-3671	38	111	,	,	PUNCT
fnp-3671	38	112	saskatoon	saskatoon	PROPN
fnp-3671	38	113	,	,	PUNCT
fnp-3671	38	114	saskatchewan	saskatchewan	PROPN
fnp-3671	38	115	,	,	PUNCT
fnp-3671	38	116	canada	canada	PROPN
fnp-3671	38	117	5	5	NUM
fnp-3671	38	118	department	department	PROPN
fnp-3671	38	119	of	of	ADP
fnp-3671	38	120	pathology	pathology	NOUN
fnp-3671	38	121	and	and	CCONJ
fnp-3671	38	122	laboratory	laboratory	NOUN
fnp-3671	38	123	medicine	medicine	NOUN
fnp-3671	38	124	,	,	PUNCT
fnp-3671	38	125	university	university	PROPN
fnp-3671	38	126	of	of	ADP
fnp-3671	38	127	saskatchewan	saskatchewan	PROPN
fnp-3671	38	128	,	,	PUNCT
fnp-3671	38	129	saskatoon	saskatoon	PROPN
fnp-3671	38	130	,	,	PUNCT
fnp-3671	38	131	saskatchewan	saskatchewan	PROPN
fnp-3671	38	132	,	,	PUNCT
fnp-3671	38	133	canada	canada	PROPN
fnp-3671	38	134	gangliogliomas	ganglioglioma	NOUN
fnp-3671	38	135	are	be	AUX
fnp-3671	38	136	important	important	ADJ
fnp-3671	38	137	to	to	PART
fnp-3671	38	138	distinguish	distinguish	VERB
fnp-3671	38	139	from	from	ADP
fnp-3671	38	140	anaplastic	anaplastic	ADJ
fnp-3671	38	141	astrocytoma	astrocytoma	NOUN
fnp-3671	38	142	and	and	CCONJ
fnp-3671	38	143	glioblastoma	glioblastoma	NOUN
fnp-3671	38	144	multiforme	multiforme	NOUN
fnp-3671	38	145	,	,	PUNCT
fnp-3671	38	146	to	to	PART
fnp-3671	38	147	avoid	avoid	VERB
fnp-3671	38	148	potentially	potentially	ADV
fnp-3671	38	149	damaging	damaging	ADJ
fnp-3671	38	150	radiation	radiation	NOUN
fnp-3671	38	151	and	and	CCONJ
fnp-3671	38	152	for	for	ADP
fnp-3671	38	153	accurate	accurate	ADJ
fnp-3671	38	154	prognostication	prognostication	NOUN
fnp-3671	38	155	.	.	PUNCT
fnp-3671	39	1	two	two	NUM
fnp-3671	39	2	patients	patient	NOUN
fnp-3671	39	3	with	with	ADP
fnp-3671	39	4	a	a	DET
fnp-3671	39	5	seizure	seizure	NOUN
fnp-3671	39	6	presentation	presentation	NOUN
fnp-3671	39	7	at	at	ADP
fnp-3671	39	8	age	age	NOUN
fnp-3671	39	9	31	31	NUM
fnp-3671	39	10	and	and	CCONJ
fnp-3671	39	11	30	30	NUM
fnp-3671	39	12	had	have	VERB
fnp-3671	39	13	large	large	ADJ
fnp-3671	39	14	,	,	PUNCT
fnp-3671	39	15	well	well	ADV
fnp-3671	39	16	demarcated	demarcate	VERB
fnp-3671	39	17	brain	brain	NOUN
fnp-3671	39	18	tumors	tumor	NOUN
fnp-3671	39	19	each	each	DET
fnp-3671	39	20	4.3	4.3	NUM
fnp-3671	39	21	cm	cm	NOUN
fnp-3671	39	22	with	with	ADP
fnp-3671	39	23	no	no	DET
fnp-3671	39	24	suggestion	suggestion	NOUN
fnp-3671	39	25	of	of	ADP
fnp-3671	39	26	diffuse	diffuse	ADJ
fnp-3671	39	27	glioma	glioma	NOUN
fnp-3671	39	28	on	on	ADP
fnp-3671	39	29	imaging	imaging	NOUN
fnp-3671	39	30	.	.	PUNCT
fnp-3671	40	1	both	both	DET
fnp-3671	40	2	patients	patient	NOUN
fnp-3671	40	3	requested	request	VERB
fnp-3671	40	4	tumor	tumor	NOUN
fnp-3671	40	5	resection	resection	NOUN
fnp-3671	40	6	.	.	PUNCT
fnp-3671	41	1	the	the	DET
fnp-3671	41	2	first	first	ADJ
fnp-3671	41	3	patient	patient	ADJ
fnp-3671	41	4	intra	intra	ADJ
fnp-3671	41	5	-	-	ADJ
fnp-3671	41	6	operatively	operatively	ADV
fnp-3671	41	7	was	be	AUX
fnp-3671	41	8	found	find	VERB
fnp-3671	41	9	to	to	PART
fnp-3671	41	10	have	have	VERB
fnp-3671	41	11	the	the	DET
fnp-3671	41	12	tumor	tumor	NOUN
fnp-3671	41	13	in	in	ADP
fnp-3671	41	14	close	close	ADJ
fnp-3671	41	15	proximity	proximity	NOUN
fnp-3671	41	16	to	to	ADP
fnp-3671	41	17	the	the	DET
fnp-3671	41	18	motor	motor	NOUN
fnp-3671	41	19	cortex	cortex	NOUN
fnp-3671	41	20	,	,	PUNCT
fnp-3671	41	21	and	and	CCONJ
fnp-3671	41	22	resection	resection	NOUN
fnp-3671	41	23	was	be	AUX
fnp-3671	41	24	thus	thus	ADV
fnp-3671	41	25	incomplete	incomplete	ADJ
fnp-3671	41	26	,	,	PUNCT
fnp-3671	41	27	leaving	leave	VERB
fnp-3671	41	28	residual	residual	ADJ
fnp-3671	41	29	tumor	tumor	NOUN
fnp-3671	41	30	in	in	ADP
fnp-3671	41	31	situ	situ	NOUN
fnp-3671	41	32	.	.	PUNCT
fnp-3671	42	1	the	the	DET
fnp-3671	42	2	second	second	ADJ
fnp-3671	42	3	patient	patient	NOUN
fnp-3671	42	4	had	have	VERB
fnp-3671	42	5	a	a	DET
fnp-3671	42	6	gross	gross	ADJ
fnp-3671	42	7	total	total	ADJ
fnp-3671	42	8	resection	resection	NOUN
fnp-3671	42	9	.	.	PUNCT
fnp-3671	43	1	an	an	DET
fnp-3671	43	2	initial	initial	ADJ
fnp-3671	43	3	diagnosis	diagnosis	NOUN
fnp-3671	43	4	of	of	ADP
fnp-3671	43	5	ganglioglioma	ganglioglioma	NOUN
fnp-3671	43	6	,	,	PUNCT
fnp-3671	43	7	was	be	AUX
fnp-3671	43	8	changed	change	VERB
fnp-3671	43	9	to	to	ADP
fnp-3671	43	10	malignant	malignant	ADJ
fnp-3671	43	11	astrocytoma	astrocytoma	NOUN
fnp-3671	43	12	based	base	VERB
fnp-3671	43	13	on	on	ADP
fnp-3671	43	14	idh1	idh1	PROPN
fnp-3671	43	15	mutation	mutation	PROPN
fnp-3671	43	16	,	,	PUNCT
fnp-3671	43	17	loss	loss	NOUN
fnp-3671	43	18	of	of	ADP
fnp-3671	43	19	atrx	atrx	ADJ
fnp-3671	43	20	,	,	PUNCT
fnp-3671	43	21	abundant	abundant	ADJ
fnp-3671	43	22	mitoses	mitose	NOUN
fnp-3671	43	23	and	and	CCONJ
fnp-3671	43	24	a	a	DET
fnp-3671	43	25	high	high	ADJ
fnp-3671	43	26	ki67	ki67	PROPN
fnp-3671	43	27	labelling	labelling	NOUN
fnp-3671	43	28	index	index	NOUN
fnp-3671	43	29	.	.	PUNCT
fnp-3671	44	1	conventional	conventional	ADJ
fnp-3671	44	2	histology	histology	NOUN
fnp-3671	44	3	revealed	reveal	VERB
fnp-3671	44	4	glial	glial	ADJ
fnp-3671	44	5	,	,	PUNCT
fnp-3671	44	6	neuronal	neuronal	ADJ
fnp-3671	44	7	and	and	CCONJ
fnp-3671	44	8	intermediate	intermediate	ADJ
fnp-3671	44	9	forms	form	NOUN
fnp-3671	44	10	in	in	ADP
fnp-3671	44	11	both	both	DET
fnp-3671	44	12	tumors	tumor	NOUN
fnp-3671	44	13	.	.	PUNCT
fnp-3671	45	1	both	both	DET
fnp-3671	45	2	patients	patient	NOUN
fnp-3671	45	3	declined	decline	VERB
fnp-3671	45	4	treatment	treatment	NOUN
fnp-3671	45	5	following	follow	VERB
fnp-3671	45	6	neurosurgery	neurosurgery	NOUN
fnp-3671	45	7	and	and	CCONJ
fnp-3671	45	8	remain	remain	VERB
fnp-3671	45	9	without	without	ADP
fnp-3671	45	10	tumor	tumor	NOUN
fnp-3671	45	11	growth	growth	NOUN
fnp-3671	45	12	on	on	ADP
fnp-3671	45	13	neuroimaging	neuroimage	VERB
fnp-3671	45	14	at	at	ADP
fnp-3671	45	15	6	6	NUM
fnp-3671	45	16	and	and	CCONJ
fnp-3671	45	17	3	3	NUM
fnp-3671	45	18	years	year	NOUN
fnp-3671	45	19	later	later	ADV
fnp-3671	45	20	,	,	PUNCT
fnp-3671	45	21	respectively	respectively	ADV
fnp-3671	45	22	.	.	PUNCT
fnp-3671	46	1	the	the	DET
fnp-3671	46	2	findings	finding	NOUN
fnp-3671	46	3	illustrate	illustrate	VERB
fnp-3671	46	4	the	the	DET
fnp-3671	46	5	conundrum	conundrum	NOUN
fnp-3671	46	6	of	of	ADP
fnp-3671	46	7	tumors	tumor	NOUN
fnp-3671	46	8	diagnosed	diagnose	VERB
fnp-3671	46	9	as	as	ADP
fnp-3671	46	10	malignant	malignant	ADJ
fnp-3671	46	11	astrocytomas	astrocytoma	NOUN
fnp-3671	46	12	based	base	VERB
fnp-3671	46	13	on	on	ADP
fnp-3671	46	14	molecular	molecular	ADJ
fnp-3671	46	15	profile	profile	NOUN
fnp-3671	46	16	,	,	PUNCT
fnp-3671	46	17	but	but	CCONJ
fnp-3671	46	18	showing	show	VERB
fnp-3671	46	19	no	no	DET
fnp-3671	46	20	growth	growth	NOUN
fnp-3671	46	21	after	after	ADP
fnp-3671	46	22	no	no	DET
fnp-3671	46	23	treatment	treatment	NOUN
fnp-3671	46	24	,	,	PUNCT
fnp-3671	46	25	as	as	ADV
fnp-3671	46	26	well	well	ADV
fnp-3671	46	27	as	as	ADP
fnp-3671	46	28	the	the	DET
fnp-3671	46	29	superiority	superiority	NOUN
fnp-3671	46	30	of	of	ADP
fnp-3671	46	31	resection	resection	NOUN
fnp-3671	46	32	over	over	ADP
fnp-3671	46	33	needle	needle	NOUN
fnp-3671	46	34	biopsy	biopsy	NOUN
fnp-3671	46	35	,	,	PUNCT
fnp-3671	46	36	as	as	SCONJ
fnp-3671	46	37	the	the	DET
fnp-3671	46	38	first	first	ADJ
fnp-3671	46	39	tumor	tumor	NOUN
fnp-3671	46	40	was	be	AUX
fnp-3671	46	41	called	call	VERB
fnp-3671	46	42	a	a	DET
fnp-3671	46	43	diffuse	diffuse	NOUN
fnp-3671	46	44	astrocytoma	astrocytoma	NOUN
fnp-3671	46	45	on	on	ADP
fnp-3671	46	46	a	a	DET
fnp-3671	46	47	needle	needle	NOUN
fnp-3671	46	48	biopsy	biopsy	NOUN
fnp-3671	46	49	prior	prior	ADV
fnp-3671	46	50	to	to	ADP
fnp-3671	46	51	resection	resection	NOUN
fnp-3671	46	52	.	.	PUNCT
fnp-3671	47	1	without	without	ADP
fnp-3671	47	2	diffuse	diffuse	NOUN
fnp-3671	47	3	astrocytoma	astrocytoma	NOUN
fnp-3671	47	4	appearing	appear	VERB
fnp-3671	47	5	on	on	ADP
fnp-3671	47	6	long	long	ADJ
fnp-3671	47	7	-	-	PUNCT
fnp-3671	47	8	term	term	NOUN
fnp-3671	47	9	follow	follow	NOUN
fnp-3671	47	10	-	-	PUNCT
fnp-3671	47	11	up	up	NOUN
fnp-3671	47	12	in	in	ADP
fnp-3671	47	13	the	the	DET
fnp-3671	47	14	absence	absence	NOUN
fnp-3671	47	15	of	of	ADP
fnp-3671	47	16	radiochemotherapy	radiochemotherapy	NOUN
fnp-3671	47	17	,	,	PUNCT
fnp-3671	47	18	a	a	DET
fnp-3671	47	19	diagnosis	diagnosis	NOUN
fnp-3671	47	20	of	of	ADP
fnp-3671	47	21	diffuse	diffuse	NOUN
fnp-3671	47	22	,	,	PUNCT
fnp-3671	47	23	malignant	malignant	ADJ
fnp-3671	47	24	astrocytoma	astrocytoma	NOUN
fnp-3671	47	25	is	be	AUX
fnp-3671	47	26	increasingly	increasingly	ADV
fnp-3671	47	27	untenable	untenable	ADJ
fnp-3671	47	28	as	as	SCONJ
fnp-3671	47	29	years	year	NOUN
fnp-3671	47	30	pass	pass	VERB
fnp-3671	47	31	.	.	PUNCT
fnp-3671	48	1	both	both	DET
fnp-3671	48	2	patients	patient	NOUN
fnp-3671	48	3	and	and	CCONJ
fnp-3671	48	4	their	their	PRON
fnp-3671	48	5	clinicians	clinician	NOUN
fnp-3671	48	6	question	question	VERB
fnp-3671	48	7	the	the	DET
fnp-3671	48	8	malignant	malignant	ADJ
fnp-3671	48	9	diagnosis	diagnosis	NOUN
fnp-3671	48	10	.	.	PUNCT
fnp-3671	49	1	gangliogliomas	ganglioglioma	NOUN
fnp-3671	49	2	have	have	AUX
fnp-3671	49	3	been	be	AUX
fnp-3671	49	4	reported	report	VERB
fnp-3671	49	5	with	with	ADP
fnp-3671	49	6	idh	idh	NOUN
fnp-3671	49	7	mutation	mutation	NOUN
fnp-3671	49	8	(	(	PUNCT
fnp-3671	49	9	brain	brain	NOUN
fnp-3671	49	10	pathol	pathol	NOUN
fnp-3671	49	11	2011	2011	NUM
fnp-3671	49	12	;	;	PUNCT
fnp-3671	49	13	21	21	NUM
fnp-3671	49	14	:	:	PUNCT
fnp-3671	49	15	564	564	NUM
fnp-3671	49	16	-	-	SYM
fnp-3671	49	17	574	574	NUM
fnp-3671	49	18	)	)	PUNCT
fnp-3671	49	19	.	.	PUNCT
fnp-3671	50	1	ganglioglioma	ganglioglioma	PROPN
fnp-3671	50	2	versus	versus	ADP
fnp-3671	50	3	diffuse	diffuse	PROPN
fnp-3671	50	4	astrocytoma	astrocytoma	NOUN
fnp-3671	50	5	remains	remain	VERB
fnp-3671	50	6	a	a	DET
fnp-3671	50	7	difficult	difficult	ADJ
fnp-3671	50	8	differential	differential	ADJ
fnp-3671	50	9	diagnosis	diagnosis	NOUN
fnp-3671	50	10	in	in	ADP
fnp-3671	50	11	neuropathology	neuropathology	NOUN
fnp-3671	50	12	.	.	PUNCT
fnp-3671	50	13	  	  	SPACE
fnp-3671	51	1	abstract	abstract	ADJ
fnp-3671	51	2	4	4	NUM
fnp-3671	51	3	free	free	ADJ
fnp-3671	51	4	neuropathol	neuropathol	NOUN
fnp-3671	51	5	2:29:7	2:29:7	NUM
fnp-3671	51	6	diagnostic	diagnostic	ADJ
fnp-3671	51	7	challenges	challenge	NOUN
fnp-3671	51	8	in	in	ADP
fnp-3671	51	9	unusual	unusual	ADJ
fnp-3671	51	10	high	high	ADJ
fnp-3671	51	11	-	-	PUNCT
fnp-3671	51	12	grade	grade	NOUN
fnp-3671	51	13	gliomas	glioma	NOUN
fnp-3671	51	14	namita	namita	PROPN
fnp-3671	51	15	sinha1	sinha1	PROPN
fnp-3671	51	16	,	,	PUNCT
fnp-3671	51	17	arie	arie	VERB
fnp-3671	51	18	perry2	perry2	PROPN
fnp-3671	51	19	1	1	NUM
fnp-3671	51	20	department	department	NOUN
fnp-3671	51	21	of	of	ADP
fnp-3671	51	22	pathology	pathology	PROPN
fnp-3671	51	23	,	,	PUNCT
fnp-3671	51	24	health	health	PROPN
fnp-3671	51	25	sciences	sciences	PROPN
fnp-3671	51	26	center	center	NOUN
fnp-3671	51	27	,	,	PUNCT
fnp-3671	51	28	university	university	NOUN
fnp-3671	51	29	of	of	ADP
fnp-3671	51	30	manitoba	manitoba	PROPN
fnp-3671	51	31	,	,	PUNCT
fnp-3671	51	32	winnipeg	winnipeg	PROPN
fnp-3671	51	33	,	,	PUNCT
fnp-3671	51	34	manitoba	manitoba	PROPN
fnp-3671	51	35	,	,	PUNCT
fnp-3671	51	36	canada	canada	PROPN
fnp-3671	51	37	2	2	NUM
fnp-3671	51	38	department	department	NOUN
fnp-3671	51	39	of	of	ADP
fnp-3671	51	40	pathology	pathology	PROPN
fnp-3671	51	41	,	,	PUNCT
fnp-3671	51	42	university	university	PROPN
fnp-3671	51	43	of	of	ADP
fnp-3671	51	44	california	california	PROPN
fnp-3671	51	45	,	,	PUNCT
fnp-3671	51	46	san	san	PROPN
fnp-3671	51	47	francisco	francisco	PROPN
fnp-3671	51	48	,	,	PUNCT
fnp-3671	51	49	california	california	PROPN
fnp-3671	51	50	,	,	PUNCT
fnp-3671	51	51	usa	usa	PROPN
fnp-3671	51	52	diagnosis	diagnosis	NOUN
fnp-3671	51	53	of	of	ADP
fnp-3671	51	54	most	most	ADJ
fnp-3671	51	55	of	of	ADP
fnp-3671	51	56	adult	adult	NOUN
fnp-3671	51	57	high	high	ADJ
fnp-3671	51	58	-	-	PUNCT
fnp-3671	51	59	grade	grade	NOUN
fnp-3671	51	60	gliomas	glioma	NOUN
fnp-3671	51	61	is	be	AUX
fnp-3671	51	62	largely	largely	ADV
fnp-3671	51	63	based	base	VERB
fnp-3671	51	64	on	on	ADP
fnp-3671	51	65	morphology	morphology	NOUN
fnp-3671	51	66	and	and	CCONJ
fnp-3671	51	67	immunohistochemistry	immunohistochemistry	NOUN
fnp-3671	51	68	,	,	PUNCT
fnp-3671	51	69	with	with	ADP
fnp-3671	51	70	an	an	DET
fnp-3671	51	71	increasing	increase	VERB
fnp-3671	51	72	role	role	NOUN
fnp-3671	51	73	of	of	ADP
fnp-3671	51	74	molecular	molecular	ADJ
fnp-3671	51	75	studies	study	NOUN
fnp-3671	51	76	to	to	PART
fnp-3671	51	77	aid	aid	VERB
fnp-3671	51	78	proper	proper	ADJ
fnp-3671	51	79	classification	classification	NOUN
fnp-3671	51	80	(	(	PUNCT
fnp-3671	51	81	idh	idh	NOUN
fnp-3671	51	82	wildtype	wildtype	NOUN
fnp-3671	51	83	and	and	CCONJ
fnp-3671	51	84	idh	idh	NOUN
fnp-3671	51	85	-	-	PUNCT
fnp-3671	51	86	mutant	mutant	NOUN
fnp-3671	51	87	gliomas	glioma	NOUN
fnp-3671	51	88	,	,	PUNCT
fnp-3671	51	89	h3k27	h3k27	PRON
fnp-3671	51	90	m	m	VERB
fnp-3671	51	91	mutant	mutant	ADJ
fnp-3671	51	92	diffuse	diffuse	ADJ
fnp-3671	51	93	midline	midline	NOUN
fnp-3671	51	94	glioma	glioma	NOUN
fnp-3671	51	95	)	)	PUNCT
fnp-3671	51	96	.	.	PUNCT
fnp-3671	52	1	on	on	ADP
fnp-3671	52	2	occasions	occasion	NOUN
fnp-3671	52	3	,	,	PUNCT
fnp-3671	52	4	despite	despite	SCONJ
fnp-3671	52	5	all	all	DET
fnp-3671	52	6	the	the	DET
fnp-3671	52	7	work	work	NOUN
fnp-3671	52	8	-	-	PUNCT
fnp-3671	52	9	up	up	NOUN
fnp-3671	52	10	,	,	PUNCT
fnp-3671	52	11	the	the	DET
fnp-3671	52	12	results	result	NOUN
fnp-3671	52	13	do	do	AUX
fnp-3671	52	14	not	not	PART
fnp-3671	52	15	allow	allow	VERB
fnp-3671	52	16	for	for	ADP
fnp-3671	52	17	a	a	DET
fnp-3671	52	18	definite	definite	ADJ
fnp-3671	52	19	diagnosis	diagnosis	NOUN
fnp-3671	52	20	that	that	PRON
fnp-3671	52	21	are	be	AUX
fnp-3671	52	22	established	establish	VERB
fnp-3671	52	23	in	in	ADP
fnp-3671	52	24	the	the	DET
fnp-3671	52	25	most	most	ADV
fnp-3671	52	26	recent	recent	ADJ
fnp-3671	52	27	who	who	PRON
fnp-3671	52	28	classification	classification	VERB
fnp-3671	52	29	.	.	PUNCT
fnp-3671	53	1	some	some	DET
fnp-3671	53	2	glial	glial	ADJ
fnp-3671	53	3	tumor	tumor	NOUN
fnp-3671	53	4	shows	show	VERB
fnp-3671	53	5	dedifferentiation	dedifferentiation	NOUN
fnp-3671	53	6	and	and	CCONJ
fnp-3671	53	7	looses	loose	VERB
fnp-3671	53	8	gfap	gfap	ADJ
fnp-3671	53	9	expression	expression	NOUN
fnp-3671	53	10	.	.	PUNCT
fnp-3671	54	1	in	in	ADP
fnp-3671	54	2	these	these	DET
fnp-3671	54	3	cases	case	NOUN
fnp-3671	54	4	,	,	PUNCT
fnp-3671	54	5	methylation	methylation	NOUN
fnp-3671	54	6	profiling	profiling	NOUN
fnp-3671	54	7	is	be	AUX
fnp-3671	54	8	a	a	DET
fnp-3671	54	9	power	power	NOUN
fnp-3671	54	10	tool	tool	NOUN
fnp-3671	54	11	in	in	ADP
fnp-3671	54	12	establishing	establish	VERB
fnp-3671	54	13	the	the	DET
fnp-3671	54	14	diagnosis	diagnosis	NOUN
fnp-3671	54	15	.	.	PUNCT
fnp-3671	55	1	therefore	therefore	ADV
fnp-3671	55	2	,	,	PUNCT
fnp-3671	55	3	it	it	PRON
fnp-3671	55	4	is	be	AUX
fnp-3671	55	5	very	very	ADV
fnp-3671	55	6	important	important	ADJ
fnp-3671	55	7	that	that	SCONJ
fnp-3671	55	8	the	the	DET
fnp-3671	55	9	tissue	tissue	NOUN
fnp-3671	55	10	should	should	AUX
fnp-3671	55	11	be	be	AUX
fnp-3671	55	12	utilized	utilize	VERB
fnp-3671	55	13	optimally	optimally	ADV
fnp-3671	55	14	and	and	CCONJ
fnp-3671	55	15	carefully	carefully	ADV
fnp-3671	55	16	especially	especially	ADV
fnp-3671	55	17	when	when	SCONJ
fnp-3671	55	18	the	the	DET
fnp-3671	55	19	biopsies	biopsy	NOUN
fnp-3671	55	20	are	be	AUX
fnp-3671	55	21	very	very	ADV
fnp-3671	55	22	small	small	ADJ
fnp-3671	55	23	and	and	CCONJ
fnp-3671	55	24	extensive	extensive	ADJ
fnp-3671	55	25	work	work	NOUN
fnp-3671	55	26	may	may	AUX
fnp-3671	55	27	be	be	AUX
fnp-3671	55	28	required	require	VERB
fnp-3671	55	29	.	.	PUNCT
fnp-3671	56	1	on	on	ADP
fnp-3671	56	2	rare	rare	ADJ
fnp-3671	56	3	occasions	occasion	NOUN
fnp-3671	56	4	,	,	PUNCT
fnp-3671	56	5	definitive	definitive	ADJ
fnp-3671	56	6	diagnosis	diagnosis	NOUN
fnp-3671	56	7	can	can	AUX
fnp-3671	56	8	be	be	AUX
fnp-3671	56	9	challenging	challenge	VERB
fnp-3671	56	10	despite	despite	SCONJ
fnp-3671	56	11	complete	complete	ADJ
fnp-3671	56	12	histological	histological	ADJ
fnp-3671	56	13	and	and	CCONJ
fnp-3671	56	14	molecular	molecular	ADJ
fnp-3671	56	15	characterization	characterization	NOUN
fnp-3671	56	16	.	.	PUNCT
fnp-3671	57	1	some	some	DET
fnp-3671	57	2	variants	variant	NOUN
fnp-3671	57	3	of	of	ADP
fnp-3671	57	4	glioblastoma	glioblastoma	NOUN
fnp-3671	57	5	may	may	AUX
fnp-3671	57	6	show	show	VERB
fnp-3671	57	7	epithelial	epithelial	ADJ
fnp-3671	57	8	or	or	CCONJ
fnp-3671	57	9	primitive	primitive	ADJ
fnp-3671	57	10	neuronal	neuronal	ADJ
fnp-3671	57	11	differentiation	differentiation	NOUN
fnp-3671	57	12	and	and	CCONJ
fnp-3671	57	13	some	some	DET
fnp-3671	57	14	variants	variant	NOUN
fnp-3671	57	15	may	may	AUX
fnp-3671	57	16	have	have	AUX
fnp-3671	57	17	increased	increase	VERB
fnp-3671	57	18	predilection	predilection	NOUN
fnp-3671	57	19	for	for	ADP
fnp-3671	57	20	csf	csf	ADJ
fnp-3671	57	21	metastasis	metastasis	NOUN
fnp-3671	57	22	and	and	CCONJ
fnp-3671	57	23	therefore	therefore	ADV
fnp-3671	57	24	it	it	PRON
fnp-3671	57	25	is	be	AUX
fnp-3671	57	26	important	important	ADJ
fnp-3671	57	27	to	to	PART
fnp-3671	57	28	subclassify	subclassify	VERB
fnp-3671	57	29	these	these	DET
fnp-3671	57	30	variants	variant	NOUN
fnp-3671	57	31	.	.	PUNCT
fnp-3671	58	1	these	these	DET
fnp-3671	58	2	challenges	challenge	NOUN
fnp-3671	58	3	will	will	AUX
fnp-3671	58	4	be	be	AUX
fnp-3671	58	5	discussed	discuss	VERB
fnp-3671	58	6	with	with	ADP
fnp-3671	58	7	some	some	DET
fnp-3671	58	8	examples	example	NOUN
fnp-3671	58	9	of	of	ADP
fnp-3671	58	10	high	high	ADJ
fnp-3671	58	11	-	-	PUNCT
fnp-3671	58	12	grade	grade	NOUN
fnp-3671	58	13	gliomas	glioma	NOUN
fnp-3671	58	14	that	that	PRON
fnp-3671	58	15	we	we	PRON
fnp-3671	58	16	received	receive	VERB
fnp-3671	58	17	in	in	ADP
fnp-3671	58	18	our	our	PRON
fnp-3671	58	19	institution	institution	NOUN
fnp-3671	58	20	at	at	ADP
fnp-3671	58	21	health	health	PROPN
fnp-3671	58	22	sciences	sciences	PROPN
fnp-3671	58	23	center	center	NOUN
fnp-3671	58	24	,	,	PUNCT
fnp-3671	58	25	university	university	NOUN
fnp-3671	58	26	of	of	ADP
fnp-3671	58	27	manitoba	manitoba	PROPN
fnp-3671	58	28	.	.	PUNCT
fnp-3671	58	29	  	  	SPACE
fnp-3671	59	1	abstract	abstract	ADJ
fnp-3671	59	2	5	5	NUM
fnp-3671	59	3	free	free	ADJ
fnp-3671	59	4	neuropathol	neuropathol	NOUN
fnp-3671	59	5	2:29:8	2:29:8	NUM
fnp-3671	59	6	regional	regional	ADJ
fnp-3671	59	7	variability	variability	NOUN
fnp-3671	59	8	of	of	ADP
fnp-3671	59	9	α	α	NOUN
fnp-3671	59	10	-	-	PUNCT
fnp-3671	59	11	synuclein	synuclein	NOUN
fnp-3671	59	12	inclusion	inclusion	NOUN
fnp-3671	59	13	size	size	NOUN
fnp-3671	59	14	in	in	ADP
fnp-3671	59	15	multiple	multiple	ADJ
fnp-3671	59	16	system	system	NOUN
fnp-3671	59	17	atrophy	atrophy	NOUN
fnp-3671	59	18	ain	ain	PROPN
fnp-3671	59	19	kim1,2,3	kim1,2,3	PROPN
fnp-3671	59	20	,	,	PUNCT
fnp-3671	59	21	ivan	ivan	PROPN
fnp-3671	59	22	martinez	martinez	PROPN
fnp-3671	59	23	-	-	PUNCT
fnp-3671	59	24	valbuena2,3	valbuena2,3	PROPN
fnp-3671	59	25	,	,	PUNCT
fnp-3671	59	26	gabor	gabor	PROPN
fnp-3671	59	27	g.	g.	PROPN
fnp-3671	59	28	kovacs1,2,3	kovacs1,2,3	PROPN
fnp-3671	59	29	*	*	PROPN
fnp-3671	59	30	1	1	NUM
fnp-3671	59	31	department	department	NOUN
fnp-3671	59	32	of	of	ADP
fnp-3671	59	33	laboratory	laboratory	PROPN
fnp-3671	59	34	medicine	medicine	PROPN
fnp-3671	59	35	&	&	CCONJ
fnp-3671	59	36	pathobiology	pathobiology	NOUN
fnp-3671	59	37	,	,	PUNCT
fnp-3671	59	38	university	university	PROPN
fnp-3671	59	39	of	of	ADP
fnp-3671	59	40	toronto	toronto	PROPN
fnp-3671	59	41	,	,	PUNCT
fnp-3671	59	42	ontario	ontario	PROPN
fnp-3671	59	43	,	,	PUNCT
fnp-3671	59	44	canada	canada	PROPN
fnp-3671	59	45	2	2	NUM
fnp-3671	59	46	tanz	tanz	PROPN
fnp-3671	59	47	centre	centre	NOUN
fnp-3671	59	48	for	for	ADP
fnp-3671	59	49	research	research	NOUN
fnp-3671	59	50	in	in	ADP
fnp-3671	59	51	neurodegenerative	neurodegenerative	ADJ
fnp-3671	59	52	disease	disease	NOUN
fnp-3671	59	53	,	,	PUNCT
fnp-3671	59	54	university	university	PROPN
fnp-3671	59	55	of	of	ADP
fnp-3671	59	56	toronto	toronto	PROPN
fnp-3671	59	57	,	,	PUNCT
fnp-3671	59	58	ontario	ontario	PROPN
fnp-3671	59	59	,	,	PUNCT
fnp-3671	59	60	canada	canada	PROPN
fnp-3671	59	61	3	3	NUM
fnp-3671	59	62	krembil	krembil	PROPN
fnp-3671	59	63	research	research	PROPN
fnp-3671	59	64	institute	institute	PROPN
fnp-3671	59	65	,	,	PUNCT
fnp-3671	59	66	university	university	NOUN
fnp-3671	59	67	health	health	NOUN
fnp-3671	59	68	network	network	NOUN
fnp-3671	59	69	,	,	PUNCT
fnp-3671	59	70	ontario	ontario	PROPN
fnp-3671	59	71	,	,	PUNCT
fnp-3671	59	72	canada	canada	PROPN
fnp-3671	59	73	relevance	relevance	NOUN
fnp-3671	59	74	:	:	PUNCT
fnp-3671	59	75	multiple	multiple	ADJ
fnp-3671	59	76	system	system	NOUN
fnp-3671	59	77	atrophy	atrophy	NOUN
fnp-3671	59	78	(	(	PUNCT
fnp-3671	59	79	msa	msa	PROPN
fnp-3671	59	80	)	)	PUNCT
fnp-3671	59	81	patients	patient	NOUN
fnp-3671	59	82	show	show	VERB
fnp-3671	59	83	variable	variable	ADJ
fnp-3671	59	84	duration	duration	NOUN
fnp-3671	59	85	of	of	ADP
fnp-3671	59	86	illness	illness	NOUN
fnp-3671	59	87	and	and	CCONJ
fnp-3671	59	88	distinct	distinct	ADJ
fnp-3671	59	89	constellation	constellation	NOUN
fnp-3671	59	90	of	of	ADP
fnp-3671	59	91	clinical	clinical	ADJ
fnp-3671	59	92	symptoms	symptom	NOUN
fnp-3671	59	93	suggestive	suggestive	ADJ
fnp-3671	59	94	of	of	ADP
fnp-3671	59	95	different	different	ADJ
fnp-3671	59	96	pathological	pathological	ADJ
fnp-3671	59	97	α	α	NOUN
fnp-3671	59	98	-	-	PUNCT
fnp-3671	59	99	synuclein	synuclein	NOUN
fnp-3671	59	100	strains	strain	NOUN
fnp-3671	59	101	.	.	PUNCT
fnp-3671	60	1	objective	objective	NOUN
fnp-3671	60	2	:	:	PUNCT
fnp-3671	60	3	based	base	VERB
fnp-3671	60	4	on	on	ADP
fnp-3671	60	5	this	this	PRON
fnp-3671	60	6	,	,	PUNCT
fnp-3671	60	7	our	our	PRON
fnp-3671	60	8	aim	aim	NOUN
fnp-3671	60	9	is	be	AUX
fnp-3671	60	10	to	to	PART
fnp-3671	60	11	investigate	investigate	VERB
fnp-3671	60	12	whether	whether	SCONJ
fnp-3671	60	13	the	the	DET
fnp-3671	60	14	seeding	seeding	NOUN
fnp-3671	60	15	and	and	CCONJ
fnp-3671	60	16	aggregation	aggregation	NOUN
fnp-3671	60	17	process	process	NOUN
fnp-3671	60	18	of	of	ADP
fnp-3671	60	19	α	α	NOUN
fnp-3671	60	20	-	-	PUNCT
fnp-3671	60	21	synuclein	synuclein	NOUN
fnp-3671	60	22	are	be	AUX
fnp-3671	60	23	different	different	ADJ
fnp-3671	60	24	in	in	ADP
fnp-3671	60	25	msa	msa	PROPN
fnp-3671	60	26	brains	brain	NOUN
fnp-3671	60	27	,	,	PUNCT
fnp-3671	60	28	leading	lead	VERB
fnp-3671	60	29	to	to	ADP
fnp-3671	60	30	variability	variability	NOUN
fnp-3671	60	31	of	of	ADP
fnp-3671	60	32	size	size	NOUN
fnp-3671	60	33	and	and	CCONJ
fnp-3671	60	34	detectability	detectability	NOUN
fnp-3671	60	35	of	of	ADP
fnp-3671	60	36	oligodendrocytic	oligodendrocytic	ADJ
fnp-3671	60	37	inclusions	inclusion	NOUN
fnp-3671	60	38	using	use	VERB
fnp-3671	60	39	different	different	ADJ
fnp-3671	60	40	anti	anti	ADJ
fnp-3671	60	41	-	-	ADJ
fnp-3671	60	42	α	α	PRON
fnp-3671	60	43	-	-	PUNCT
fnp-3671	60	44	synuclein	synuclein	NOUN
fnp-3671	60	45	antibodies	antibodie	VERB
fnp-3671	60	46	.	.	PUNCT
fnp-3671	61	1	methods	method	NOUN
fnp-3671	61	2	:	:	PUNCT
fnp-3671	61	3	the	the	DET
fnp-3671	61	4	putamen	putaman	NOUN
fnp-3671	61	5	and	and	CCONJ
fnp-3671	61	6	cerebellum	cerebellum	NOUN
fnp-3671	61	7	of	of	ADP
fnp-3671	61	8	6	6	NUM
fnp-3671	61	9	msa	msa	PROPN
fnp-3671	61	10	cases	case	NOUN
fnp-3671	61	11	were	be	AUX
fnp-3671	61	12	immunostained	immunostaine	VERB
fnp-3671	61	13	using	use	VERB
fnp-3671	61	14	nitrated	nitrate	VERB
fnp-3671	61	15	,	,	PUNCT
fnp-3671	61	16	truncated	truncate	VERB
fnp-3671	61	17	,	,	PUNCT
fnp-3671	61	18	phosphorylated	phosphorylate	VERB
fnp-3671	61	19	and	and	CCONJ
fnp-3671	61	20	disease	disease	NOUN
fnp-3671	61	21	-	-	PUNCT
fnp-3671	61	22	specific	specific	ADJ
fnp-3671	61	23	α	α	NOUN
fnp-3671	61	24	-	-	PUNCT
fnp-3671	61	25	synuclein	synuclein	NOUN
fnp-3671	61	26	(	(	PUNCT
fnp-3671	61	27	clone	clone	NOUN
fnp-3671	61	28	5g4	5g4	NUM
fnp-3671	61	29	)	)	PUNCT
fnp-3671	61	30	antibodies	antibodie	VERB
fnp-3671	61	31	.	.	PUNCT
fnp-3671	62	1	sections	section	NOUN
fnp-3671	62	2	were	be	AUX
fnp-3671	62	3	scanned	scan	VERB
fnp-3671	62	4	using	use	VERB
fnp-3671	62	5	tissuescopetm	tissuescopetm	NOUN
fnp-3671	62	6	and	and	CCONJ
fnp-3671	62	7	images	image	NOUN
fnp-3671	62	8	were	be	AUX
fnp-3671	62	9	processed	process	VERB
fnp-3671	62	10	using	use	VERB
fnp-3671	62	11	photoshop	photoshop	NOUN
fnp-3671	62	12	(	(	PUNCT
fnp-3671	62	13	v.21.0.3	v.21.0.3	NUM
fnp-3671	62	14	)	)	PUNCT
fnp-3671	62	15	.	.	PUNCT
fnp-3671	63	1	5g4	5g4	NUM
fnp-3671	63	2	-	-	PUNCT
fnp-3671	63	3	immunoreactive	immunoreactive	ADJ
fnp-3671	63	4	oligodendrocytes	oligodendrocyte	NOUN
fnp-3671	63	5	with	with	ADP
fnp-3671	63	6	visible	visible	ADJ
fnp-3671	63	7	nucleus	nucleus	NOUN
fnp-3671	63	8	were	be	AUX
fnp-3671	63	9	optically	optically	ADV
fnp-3671	63	10	dissected	dissect	VERB
fnp-3671	63	11	and	and	CCONJ
fnp-3671	63	12	inclusion	inclusion	NOUN
fnp-3671	63	13	sizes	size	NOUN
fnp-3671	63	14	were	be	AUX
fnp-3671	63	15	evaluated	evaluate	VERB
fnp-3671	63	16	using	use	VERB
fnp-3671	63	17	algorithms	algorithm	NOUN
fnp-3671	63	18	that	that	PRON
fnp-3671	63	19	we	we	PRON
fnp-3671	63	20	developed	develop	VERB
fnp-3671	63	21	using	use	VERB
fnp-3671	63	22	the	the	DET
fnp-3671	63	23	software	software	NOUN
fnp-3671	63	24	image	image	NOUN
fnp-3671	63	25	j.	j.	PROPN
fnp-3671	63	26	results	result	VERB
fnp-3671	63	27	:	:	PUNCT
fnp-3671	63	28	the	the	DET
fnp-3671	63	29	size	size	NOUN
fnp-3671	63	30	of	of	ADP
fnp-3671	63	31	5g4	5g4	NUM
fnp-3671	63	32	-	-	PUNCT
fnp-3671	63	33	reactive	reactive	ADJ
fnp-3671	63	34	inclusions	inclusion	NOUN
fnp-3671	63	35	were	be	AUX
fnp-3671	63	36	significantly	significantly	ADV
fnp-3671	63	37	larger	large	ADJ
fnp-3671	63	38	in	in	ADP
fnp-3671	63	39	the	the	DET
fnp-3671	63	40	cerebellum	cerebellum	NOUN
fnp-3671	63	41	than	than	ADP
fnp-3671	63	42	in	in	ADP
fnp-3671	63	43	the	the	DET
fnp-3671	63	44	putamen	putaman	NOUN
fnp-3671	63	45	in	in	ADP
fnp-3671	63	46	4	4	NUM
fnp-3671	63	47	out	out	ADP
fnp-3671	63	48	of	of	ADP
fnp-3671	63	49	6	6	NUM
fnp-3671	63	50	cases	case	NOUN
fnp-3671	63	51	.	.	PUNCT
fnp-3671	64	1	in	in	ADP
fnp-3671	64	2	one	one	NUM
fnp-3671	64	3	case	case	NOUN
fnp-3671	64	4	,	,	PUNCT
fnp-3671	64	5	the	the	DET
fnp-3671	64	6	inclusion	inclusion	NOUN
fnp-3671	64	7	size	size	NOUN
fnp-3671	64	8	was	be	AUX
fnp-3671	64	9	significantly	significantly	ADV
fnp-3671	64	10	larger	large	ADJ
fnp-3671	64	11	in	in	ADP
fnp-3671	64	12	the	the	DET
fnp-3671	64	13	putamen	putaman	NOUN
fnp-3671	64	14	than	than	ADP
fnp-3671	64	15	in	in	ADP
fnp-3671	64	16	the	the	DET
fnp-3671	64	17	cerebellum	cerebellum	NOUN
fnp-3671	64	18	,	,	PUNCT
fnp-3671	64	19	while	while	SCONJ
fnp-3671	64	20	a	a	DET
fnp-3671	64	21	single	single	ADJ
fnp-3671	64	22	case	case	NOUN
fnp-3671	64	23	showed	show	VERB
fnp-3671	64	24	similar	similar	ADJ
fnp-3671	64	25	sizes	size	NOUN
fnp-3671	64	26	.	.	PUNCT
fnp-3671	65	1	in	in	ADP
fnp-3671	65	2	addition	addition	NOUN
fnp-3671	65	3	,	,	PUNCT
fnp-3671	65	4	case	case	NOUN
fnp-3671	65	5	-	-	PUNCT
fnp-3671	65	6	wise	wise	ADJ
fnp-3671	65	7	comparison	comparison	NOUN
fnp-3671	65	8	revealed	reveal	VERB
fnp-3671	65	9	significant	significant	ADJ
fnp-3671	65	10	variability	variability	NOUN
fnp-3671	65	11	between	between	ADP
fnp-3671	65	12	the	the	DET
fnp-3671	65	13	size	size	NOUN
fnp-3671	65	14	of	of	ADP
fnp-3671	65	15	inclusions	inclusion	NOUN
fnp-3671	65	16	in	in	ADP
fnp-3671	65	17	both	both	DET
fnp-3671	65	18	regions	region	NOUN
fnp-3671	65	19	.	.	PUNCT
fnp-3671	66	1	in	in	ADP
fnp-3671	66	2	addition	addition	NOUN
fnp-3671	66	3	,	,	PUNCT
fnp-3671	66	4	substantial	substantial	ADJ
fnp-3671	66	5	differences	difference	NOUN
fnp-3671	66	6	were	be	AUX
fnp-3671	66	7	noted	note	VERB
fnp-3671	66	8	between	between	ADP
fnp-3671	66	9	the	the	DET
fnp-3671	66	10	number	number	NOUN
fnp-3671	66	11	of	of	ADP
fnp-3671	66	12	inclusions	inclusion	NOUN
fnp-3671	66	13	stained	stain	VERB
fnp-3671	66	14	by	by	ADP
fnp-3671	66	15	the	the	DET
fnp-3671	66	16	different	different	ADJ
fnp-3671	66	17	α	α	NOUN
fnp-3671	66	18	-	-	PUNCT
fnp-3671	66	19	synuclein	synuclein	NOUN
fnp-3671	66	20	antibodies	antibodie	VERB
fnp-3671	66	21	.	.	PUNCT
fnp-3671	67	1	conclusions	conclusion	NOUN
fnp-3671	67	2	:	:	PUNCT
fnp-3671	67	3	we	we	PRON
fnp-3671	67	4	developed	develop	VERB
fnp-3671	67	5	a	a	DET
fnp-3671	67	6	novel	novel	ADJ
fnp-3671	67	7	computer	computer	NOUN
fnp-3671	67	8	-	-	PUNCT
fnp-3671	67	9	based	base	VERB
fnp-3671	67	10	method	method	NOUN
fnp-3671	67	11	to	to	PART
fnp-3671	67	12	measure	measure	VERB
fnp-3671	67	13	the	the	DET
fnp-3671	67	14	size	size	NOUN
fnp-3671	67	15	and	and	CCONJ
fnp-3671	67	16	number	number	NOUN
fnp-3671	67	17	of	of	ADP
fnp-3671	67	18	α	α	NOUN
fnp-3671	67	19	-	-	PUNCT
fnp-3671	67	20	synuclein	synuclein	NOUN
fnp-3671	67	21	inclusions	inclusion	NOUN
fnp-3671	67	22	in	in	ADP
fnp-3671	67	23	msa	msa	PROPN
fnp-3671	67	24	.	.	PUNCT
fnp-3671	68	1	our	our	PRON
fnp-3671	68	2	observations	observation	NOUN
fnp-3671	68	3	on	on	ADP
fnp-3671	68	4	the	the	DET
fnp-3671	68	5	variability	variability	NOUN
fnp-3671	68	6	of	of	ADP
fnp-3671	68	7	size	size	NOUN
fnp-3671	68	8	and	and	CCONJ
fnp-3671	68	9	number	number	NOUN
fnp-3671	68	10	of	of	ADP
fnp-3671	68	11	inclusions	inclusion	NOUN
fnp-3671	68	12	,	,	PUNCT
fnp-3671	68	13	detected	detect	VERB
fnp-3671	68	14	by	by	ADP
fnp-3671	68	15	different	different	ADJ
fnp-3671	68	16	α	α	PROPN
fnp-3671	68	17	-	-	PUNCT
fnp-3671	68	18	synuclein	synuclein	NOUN
fnp-3671	68	19	epitopes	epitope	NOUN
fnp-3671	68	20	between	between	ADP
fnp-3671	68	21	brain	brain	NOUN
fnp-3671	68	22	regions	region	NOUN
fnp-3671	68	23	and	and	CCONJ
fnp-3671	68	24	cases	case	NOUN
fnp-3671	68	25	,	,	PUNCT
fnp-3671	68	26	support	support	VERB
fnp-3671	68	27	the	the	DET
fnp-3671	68	28	notion	notion	NOUN
fnp-3671	68	29	of	of	ADP
fnp-3671	68	30	distinct	distinct	ADJ
fnp-3671	68	31	subtypes	subtype	NOUN
fnp-3671	68	32	of	of	ADP
fnp-3671	68	33	disease	disease	NOUN
fnp-3671	68	34	.	.	PUNCT
fnp-3671	69	1	our	our	PRON
fnp-3671	69	2	study	study	NOUN
fnp-3671	69	3	further	far	ADV
fnp-3671	69	4	provides	provide	VERB
fnp-3671	69	5	a	a	DET
fnp-3671	69	6	first	first	ADJ
fnp-3671	69	7	step	step	NOUN
fnp-3671	69	8	to	to	ADP
fnp-3671	69	9	developing	develop	VERB
fnp-3671	69	10	ai	ai	NOUN
fnp-3671	69	11	-	-	PUNCT
fnp-3671	69	12	based	base	VERB
fnp-3671	69	13	evaluation	evaluation	NOUN
fnp-3671	69	14	strategies	strategy	NOUN
fnp-3671	69	15	for	for	ADP
fnp-3671	69	16	large	large	ADJ
fnp-3671	69	17	scale	scale	NOUN
fnp-3671	69	18	comparative	comparative	ADJ
fnp-3671	69	19	studies	study	NOUN
fnp-3671	69	20	.	.	PUNCT
fnp-3671	69	21	  	  	SPACE
fnp-3671	70	1	abstract	abstract	ADJ
fnp-3671	70	2	6	6	NUM
fnp-3671	70	3	free	free	ADJ
fnp-3671	70	4	neuropathol	neuropathol	NOUN
fnp-3671	70	5	2:29:9	2:29:9	NUM
fnp-3671	70	6	cognitive	cognitive	ADJ
fnp-3671	70	7	resilience	resilience	NOUN
fnp-3671	70	8	in	in	ADP
fnp-3671	70	9	individuals	individual	NOUN
fnp-3671	70	10	with	with	ADP
fnp-3671	70	11	severe	severe	ADJ
fnp-3671	70	12	alzheimer	alzheimer	PROPN
fnp-3671	70	13	’s	’s	PART
fnp-3671	70	14	disease	disease	NOUN
fnp-3671	70	15	neuropathology	neuropathology	NOUN
fnp-3671	70	16	narges	narge	VERB
fnp-3671	70	17	ahangari1	ahangari1	PROPN
fnp-3671	70	18	,	,	PUNCT
fnp-3671	70	19	corinne	corinne	PROPN
fnp-3671	70	20	e.	e.	PROPN
fnp-3671	70	21	fischer2,3,4	fischer2,3,4	PROPN
fnp-3671	70	22	,	,	PUNCT
fnp-3671	70	23	tom	tom	PROPN
fnp-3671	70	24	a.	a.	NOUN
fnp-3671	70	25	schweizer2,4,5	schweizer2,4,5	PROPN
fnp-3671	70	26	,	,	PUNCT
fnp-3671	70	27	david	david	PROPN
fnp-3671	70	28	g.	g.	PROPN
fnp-3671	70	29	munoz1,2,6	munoz1,2,6	PROPN
fnp-3671	71	1	1	1	NUM
fnp-3671	71	2	division	division	NOUN
fnp-3671	71	3	of	of	ADP
fnp-3671	71	4	pathology	pathology	PROPN
fnp-3671	71	5	,	,	PUNCT
fnp-3671	71	6	st	st	PROPN
fnp-3671	71	7	.	.	PROPN
fnp-3671	71	8	michael	michael	PROPN
fnp-3671	71	9	’s	’s	PART
fnp-3671	71	10	hospital	hospital	PROPN
fnp-3671	71	11	,	,	PUNCT
fnp-3671	71	12	toronto	toronto	PROPN
fnp-3671	71	13	,	,	PUNCT
fnp-3671	71	14	ontario	ontario	PROPN
fnp-3671	71	15	,	,	PUNCT
fnp-3671	71	16	canada	canada	PROPN
fnp-3671	71	17	2	2	NUM
fnp-3671	71	18	keenan	keenan	PROPN
fnp-3671	71	19	research	research	NOUN
fnp-3671	71	20	centre	centre	PROPN
fnp-3671	71	21	for	for	ADP
fnp-3671	71	22	biomedical	biomedical	ADJ
fnp-3671	71	23	research	research	NOUN
fnp-3671	71	24	,	,	PUNCT
fnp-3671	71	25	the	the	DET
fnp-3671	71	26	li	li	PROPN
fnp-3671	71	27	ka	ka	PROPN
fnp-3671	71	28	shing	shing	PROPN
fnp-3671	71	29	knowledge	knowledge	PROPN
fnp-3671	71	30	institute	institute	PROPN
fnp-3671	71	31	,	,	PUNCT
fnp-3671	71	32	st.michael	st.michael	PROPN
fnp-3671	71	33	’s	’s	PART
fnp-3671	71	34	hospital	hospital	NOUN
fnp-3671	71	35	,	,	PUNCT
fnp-3671	71	36	toronto	toronto	PROPN
fnp-3671	71	37	,	,	PUNCT
fnp-3671	71	38	ontario	ontario	PROPN
fnp-3671	71	39	,	,	PUNCT
fnp-3671	71	40	canada	canada	PROPN
fnp-3671	71	41	3	3	NUM
fnp-3671	71	42	department	department	PROPN
fnp-3671	71	43	of	of	ADP
fnp-3671	71	44	psychiatry	psychiatry	NOUN
fnp-3671	71	45	,	,	PUNCT
fnp-3671	71	46	faculty	faculty	NOUN
fnp-3671	71	47	of	of	ADP
fnp-3671	71	48	medicine	medicine	NOUN
fnp-3671	71	49	,	,	PUNCT
fnp-3671	71	50	university	university	PROPN
fnp-3671	71	51	of	of	ADP
fnp-3671	71	52	toronto	toronto	PROPN
fnp-3671	71	53	,	,	PUNCT
fnp-3671	71	54	ontario	ontario	PROPN
fnp-3671	71	55	,	,	PUNCT
fnp-3671	71	56	canada	canada	PROPN
fnp-3671	71	57	4	4	NUM
fnp-3671	71	58	institute	institute	PROPN
fnp-3671	71	59	of	of	ADP
fnp-3671	71	60	medical	medical	ADJ
fnp-3671	71	61	sciences	sciences	PROPN
fnp-3671	71	62	,	,	PUNCT
fnp-3671	71	63	university	university	PROPN
fnp-3671	71	64	of	of	ADP
fnp-3671	71	65	toronto	toronto	PROPN
fnp-3671	71	66	,	,	PUNCT
fnp-3671	71	67	toronto	toronto	PROPN
fnp-3671	71	68	,	,	PUNCT
fnp-3671	71	69	ontario	ontario	PROPN
fnp-3671	71	70	,	,	PUNCT
fnp-3671	71	71	canada	canada	PROPN
fnp-3671	71	72	5	5	NUM
fnp-3671	71	73	division	division	NOUN
fnp-3671	71	74	of	of	ADP
fnp-3671	71	75	neurosurgery	neurosurgery	NOUN
fnp-3671	71	76	,	,	PUNCT
fnp-3671	71	77	faculty	faculty	NOUN
fnp-3671	71	78	of	of	ADP
fnp-3671	71	79	medicine	medicine	NOUN
fnp-3671	71	80	,	,	PUNCT
fnp-3671	71	81	university	university	PROPN
fnp-3671	71	82	of	of	ADP
fnp-3671	71	83	toronto	toronto	PROPN
fnp-3671	71	84	,	,	PUNCT
fnp-3671	71	85	ontario	ontario	PROPN
fnp-3671	71	86	,	,	PUNCT
fnp-3671	71	87	canada	canada	PROPN
fnp-3671	71	88	6	6	NUM
fnp-3671	71	89	department	department	NOUN
fnp-3671	71	90	of	of	ADP
fnp-3671	71	91	laboratory	laboratory	NOUN
fnp-3671	71	92	medicine	medicine	NOUN
fnp-3671	71	93	and	and	CCONJ
fnp-3671	71	94	pathobiology	pathobiology	NOUN
fnp-3671	71	95	,	,	PUNCT
fnp-3671	71	96	university	university	PROPN
fnp-3671	71	97	of	of	ADP
fnp-3671	71	98	toronto	toronto	PROPN
fnp-3671	71	99	,	,	PUNCT
fnp-3671	71	100	ontario	ontario	PROPN
fnp-3671	71	101	,	,	PUNCT
fnp-3671	71	102	canada	canada	PROPN
fnp-3671	71	103	we	we	PRON
fnp-3671	71	104	sought	seek	VERB
fnp-3671	71	105	to	to	PART
fnp-3671	71	106	identify	identify	VERB
fnp-3671	71	107	demographic	demographic	ADJ
fnp-3671	71	108	,	,	PUNCT
fnp-3671	71	109	clinical	clinical	ADJ
fnp-3671	71	110	,	,	PUNCT
fnp-3671	71	111	genetic	genetic	ADJ
fnp-3671	71	112	,	,	PUNCT
fnp-3671	71	113	and	and	CCONJ
fnp-3671	71	114	neuropathological	neuropathological	ADJ
fnp-3671	71	115	features	feature	NOUN
fnp-3671	71	116	associated	associate	VERB
fnp-3671	71	117	with	with	ADP
fnp-3671	71	118	cognitive	cognitive	ADJ
fnp-3671	71	119	resilience	resilience	NOUN
fnp-3671	71	120	in	in	ADP
fnp-3671	71	121	subjects	subject	NOUN
fnp-3671	71	122	with	with	ADP
fnp-3671	71	123	severe	severe	ADJ
fnp-3671	71	124	alzheimer	alzheimer	PROPN
fnp-3671	71	125	’s	’s	PART
fnp-3671	71	126	disease	disease	NOUN
fnp-3671	71	127	(	(	PUNCT
fnp-3671	71	128	ad	ad	NOUN
fnp-3671	71	129	)	)	PUNCT
fnp-3671	71	130	neuropathology	neuropathology	NOUN
fnp-3671	71	131	.	.	PUNCT
fnp-3671	72	1	data	datum	NOUN
fnp-3671	72	2	for	for	ADP
fnp-3671	72	3	this	this	DET
fnp-3671	72	4	study	study	NOUN
fnp-3671	72	5	was	be	AUX
fnp-3671	72	6	obtained	obtain	VERB
fnp-3671	72	7	from	from	ADP
fnp-3671	72	8	a	a	DET
fnp-3671	72	9	national	national	PROPN
fnp-3671	72	10	alzheimer	alzheimer	PROPN
fnp-3671	72	11	’s	’s	PART
fnp-3671	72	12	coordinating	coordinate	VERB
fnp-3671	72	13	centre	centre	NOUN
fnp-3671	72	14	(	(	PUNCT
fnp-3671	72	15	nacc	nacc	NOUN
fnp-3671	72	16	)	)	PUNCT
fnp-3671	72	17	dataset	dataset	NOUN
fnp-3671	72	18	.	.	PUNCT
fnp-3671	73	1	study	study	NOUN
fnp-3671	73	2	inclusion	inclusion	NOUN
fnp-3671	73	3	criteria	criterion	NOUN
fnp-3671	73	4	are	be	AUX
fnp-3671	73	5	as	as	SCONJ
fnp-3671	73	6	follows	follow	VERB
fnp-3671	73	7	:	:	PUNCT
fnp-3671	73	8	severe	severe	ADJ
fnp-3671	73	9	ad	ad	NOUN
fnp-3671	73	10	pathology	pathology	NOUN
fnp-3671	73	11	,	,	PUNCT
fnp-3671	73	12	i.e.	i.e.	X
fnp-3671	73	13	,	,	PUNCT
fnp-3671	73	14	frequent	frequent	ADJ
fnp-3671	73	15	neuritic	neuritic	ADJ
fnp-3671	73	16	plaques	plaque	NOUN
fnp-3671	73	17	and	and	CCONJ
fnp-3671	73	18	braak	braak	PROPN
fnp-3671	73	19	&	&	CCONJ
fnp-3671	73	20	braak	braak	PROPN
fnp-3671	73	21	stage	stage	PROPN
fnp-3671	73	22	v	v	PROPN
fnp-3671	73	23	/	/	SYM
fnp-3671	73	24	vi	vi	PROPN
fnp-3671	73	25	pathology	pathology	NOUN
fnp-3671	73	26	,	,	PUNCT
fnp-3671	73	27	interval	interval	NOUN
fnp-3671	73	28	between	between	ADP
fnp-3671	73	29	last	last	ADJ
fnp-3671	73	30	visit	visit	NOUN
fnp-3671	73	31	and	and	CCONJ
fnp-3671	73	32	death	death	NOUN
fnp-3671	73	33	≤	≤	NUM
fnp-3671	73	34	2	2	NUM
fnp-3671	73	35	years	year	NOUN
fnp-3671	73	36	,	,	PUNCT
fnp-3671	73	37	and	and	CCONJ
fnp-3671	73	38	absence	absence	NOUN
fnp-3671	73	39	of	of	ADP
fnp-3671	73	40	other	other	ADJ
fnp-3671	73	41	primary	primary	ADJ
fnp-3671	73	42	neuropathology	neuropathology	NOUN
fnp-3671	73	43	diagnoses	diagnose	VERB
fnp-3671	73	44	.	.	PUNCT
fnp-3671	74	1	cognition	cognition	NOUN
fnp-3671	74	2	was	be	AUX
fnp-3671	74	3	assessed	assess	VERB
fnp-3671	74	4	by	by	ADP
fnp-3671	74	5	the	the	DET
fnp-3671	74	6	mini	mini	ADJ
fnp-3671	74	7	-	-	ADJ
fnp-3671	74	8	mental	mental	ADJ
fnp-3671	74	9	status	status	NOUN
fnp-3671	74	10	examination	examination	NOUN
fnp-3671	74	11	(	(	PUNCT
fnp-3671	74	12	mmse	mmse	ADJ
fnp-3671	74	13	)	)	PUNCT
fnp-3671	74	14	score	score	NOUN
fnp-3671	74	15	.	.	PUNCT
fnp-3671	75	1	a	a	DET
fnp-3671	75	2	total	total	NOUN
fnp-3671	75	3	of	of	ADP
fnp-3671	75	4	654	654	NUM
fnp-3671	75	5	cases	case	NOUN
fnp-3671	75	6	met	meet	VERB
fnp-3671	75	7	our	our	PRON
fnp-3671	75	8	criteria	criterion	NOUN
fnp-3671	75	9	.	.	PUNCT
fnp-3671	76	1	of	of	ADP
fnp-3671	76	2	these	these	PRON
fnp-3671	76	3	,	,	PUNCT
fnp-3671	76	4	59	59	NUM
fnp-3671	76	5	(	(	PUNCT
fnp-3671	76	6	9	9	NUM
fnp-3671	76	7	%	%	NOUN
fnp-3671	76	8	)	)	PUNCT
fnp-3671	76	9	persons	person	NOUN
fnp-3671	76	10	had	have	VERB
fnp-3671	76	11	mmse	mmse	ADJ
fnp-3671	76	12	scores	score	NOUN
fnp-3671	76	13	≥24	≥24	PROPN
fnp-3671	76	14	at	at	ADP
fnp-3671	76	15	their	their	PRON
fnp-3671	76	16	last	last	ADJ
fnp-3671	76	17	visit	visit	NOUN
fnp-3671	76	18	and	and	CCONJ
fnp-3671	76	19	were	be	AUX
fnp-3671	76	20	categorized	categorize	VERB
fnp-3671	76	21	as	as	ADP
fnp-3671	76	22	cognitively	cognitively	ADV
fnp-3671	76	23	resilient	resilient	ADJ
fnp-3671	76	24	.	.	PUNCT
fnp-3671	77	1	first	first	ADV
fnp-3671	77	2	,	,	PUNCT
fnp-3671	77	3	bivariate	bivariate	ADJ
fnp-3671	77	4	analysis	analysis	NOUN
fnp-3671	77	5	was	be	AUX
fnp-3671	77	6	done	do	VERB
fnp-3671	77	7	to	to	PART
fnp-3671	77	8	compare	compare	VERB
fnp-3671	77	9	resilient	resilient	ADJ
fnp-3671	77	10	with	with	ADP
fnp-3671	77	11	non	non	ADJ
fnp-3671	77	12	-	-	ADJ
fnp-3671	77	13	resilient	resilient	ADJ
fnp-3671	77	14	groups	group	NOUN
fnp-3671	77	15	.	.	PUNCT
fnp-3671	78	1	then	then	ADV
fnp-3671	78	2	,	,	PUNCT
fnp-3671	78	3	variables	variable	NOUN
fnp-3671	78	4	with	with	ADP
fnp-3671	78	5	significant	significant	ADJ
fnp-3671	78	6	results	result	NOUN
fnp-3671	78	7	were	be	AUX
fnp-3671	78	8	entered	enter	VERB
fnp-3671	78	9	into	into	ADP
fnp-3671	78	10	the	the	DET
fnp-3671	78	11	multivariable	multivariable	ADJ
fnp-3671	78	12	model	model	NOUN
fnp-3671	78	13	.	.	PUNCT
fnp-3671	79	1	based	base	VERB
fnp-3671	79	2	on	on	ADP
fnp-3671	79	3	our	our	PRON
fnp-3671	79	4	binary	binary	ADJ
fnp-3671	79	5	logistic	logistic	ADJ
fnp-3671	79	6	regression	regression	NOUN
fnp-3671	79	7	model	model	NOUN
fnp-3671	79	8	,	,	PUNCT
fnp-3671	79	9	resilient	resilient	ADJ
fnp-3671	79	10	subjects	subject	NOUN
fnp-3671	79	11	were	be	AUX
fnp-3671	79	12	older	old	ADJ
fnp-3671	79	13	(	(	PUNCT
fnp-3671	79	14	odds	odd	NOUN
fnp-3671	79	15	ratio	ratio	NOUN
fnp-3671	79	16	[	[	X
fnp-3671	79	17	or]=1.03	or]=1.03	NUM
fnp-3671	79	18	;	;	PUNCT
fnp-3671	79	19	95	95	NUM
fnp-3671	79	20	%	%	NOUN
fnp-3671	79	21	confidence	confidence	NOUN
fnp-3671	79	22	interval	interval	NOUN
fnp-3671	79	23	[	[	X
fnp-3671	79	24	ci]=1–1.07	ci]=1–1.07	NOUN
fnp-3671	79	25	)	)	PUNCT
fnp-3671	79	26	,	,	PUNCT
fnp-3671	79	27	had	have	VERB
fnp-3671	79	28	more	more	ADJ
fnp-3671	79	29	years	year	NOUN
fnp-3671	79	30	of	of	ADP
fnp-3671	79	31	education	education	NOUN
fnp-3671	79	32	(	(	PUNCT
fnp-3671	79	33	or=1.16	or=1.16	NOUN
fnp-3671	79	34	;	;	PUNCT
fnp-3671	79	35	95	95	NUM
fnp-3671	79	36	%	%	NOUN
fnp-3671	79	37	ci=1.04	ci=1.04	NOUN
fnp-3671	79	38	-	-	NOUN
fnp-3671	79	39	1.29	1.29	NUM
fnp-3671	79	40	)	)	PUNCT
fnp-3671	79	41	,	,	PUNCT
fnp-3671	79	42	had	have	VERB
fnp-3671	79	43	lower	low	ADJ
fnp-3671	79	44	bmi	bmi	NOUN
fnp-3671	79	45	(	(	PUNCT
fnp-3671	79	46	or=0.91	or=0.91	NOUN
fnp-3671	79	47	;	;	PUNCT
fnp-3671	79	48	95	95	NUM
fnp-3671	79	49	%	%	NOUN
fnp-3671	79	50	ci=0.85	ci=0.85	NOUN
fnp-3671	79	51	-	-	PUNCT
fnp-3671	79	52	0.99	0.99	NUM
fnp-3671	79	53	)	)	PUNCT
fnp-3671	79	54	,	,	PUNCT
fnp-3671	79	55	were	be	AUX
fnp-3671	79	56	more	more	ADV
fnp-3671	79	57	likely	likely	ADJ
fnp-3671	79	58	to	to	PART
fnp-3671	79	59	be	be	AUX
fnp-3671	79	60	a	a	DET
fnp-3671	79	61	smoker	smoker	NOUN
fnp-3671	79	62	(	(	PUNCT
fnp-3671	79	63	or=2.78	or=2.78	ADJ
fnp-3671	79	64	;	;	PUNCT
fnp-3671	79	65	95	95	NUM
fnp-3671	79	66	%	%	NOUN
fnp-3671	79	67	ci=1.45	ci=1.45	NOUN
fnp-3671	79	68	-	-	PUNCT
fnp-3671	79	69	5.34	5.34	NUM
fnp-3671	79	70	)	)	PUNCT
fnp-3671	79	71	,	,	PUNCT
fnp-3671	79	72	and	and	CCONJ
fnp-3671	79	73	were	be	AUX
fnp-3671	79	74	more	more	ADV
fnp-3671	79	75	likely	likely	ADJ
fnp-3671	79	76	to	to	PART
fnp-3671	79	77	use	use	VERB
fnp-3671	79	78	an	an	DET
fnp-3671	79	79	anticoagulant	anticoagulant	NOUN
fnp-3671	79	80	/	/	SYM
fnp-3671	79	81	antiplatelet	antiplatelet	NOUN
fnp-3671	79	82	at	at	ADP
fnp-3671	79	83	last	last	ADJ
fnp-3671	79	84	visit	visit	NOUN
fnp-3671	79	85	compared	compare	VERB
fnp-3671	79	86	with	with	ADP
fnp-3671	79	87	subjects	subject	NOUN
fnp-3671	79	88	with	with	ADP
fnp-3671	79	89	impaired	impaired	ADJ
fnp-3671	79	90	cognition	cognition	NOUN
fnp-3671	79	91	(	(	PUNCT
fnp-3671	79	92	or=1.87	or=1.87	PROPN
fnp-3671	79	93	;	;	PUNCT
fnp-3671	79	94	95	95	NUM
fnp-3671	79	95	%	%	NOUN
fnp-3671	79	96	ci=1.01	ci=1.01	NOUN
fnp-3671	79	97	-	-	PUNCT
fnp-3671	79	98	3.48	3.48	NUM
fnp-3671	79	99	)	)	PUNCT
fnp-3671	79	100	.	.	PUNCT
fnp-3671	80	1	in	in	ADP
fnp-3671	80	2	addition	addition	NOUN
fnp-3671	80	3	to	to	ADP
fnp-3671	80	4	expected	expect	VERB
fnp-3671	80	5	protective	protective	ADJ
fnp-3671	80	6	factors	factor	NOUN
fnp-3671	80	7	such	such	ADJ
fnp-3671	80	8	as	as	ADP
fnp-3671	80	9	higher	high	ADJ
fnp-3671	80	10	education	education	NOUN
fnp-3671	80	11	and	and	CCONJ
fnp-3671	80	12	lower	low	ADJ
fnp-3671	80	13	bmi	bmi	NOUN
fnp-3671	80	14	,	,	PUNCT
fnp-3671	80	15	our	our	PRON
fnp-3671	80	16	results	result	NOUN
fnp-3671	80	17	showed	show	VERB
fnp-3671	80	18	that	that	SCONJ
fnp-3671	80	19	more	more	ADJ
fnp-3671	80	20	smoking	smoking	NOUN
fnp-3671	80	21	and	and	CCONJ
fnp-3671	80	22	frequent	frequent	ADJ
fnp-3671	80	23	use	use	NOUN
fnp-3671	80	24	of	of	ADP
fnp-3671	80	25	an	an	DET
fnp-3671	80	26	anticoagulant	anticoagulant	NOUN
fnp-3671	80	27	/	/	SYM
fnp-3671	80	28	antiplatelet	antiplatelet	NOUN
fnp-3671	80	29	at	at	ADP
fnp-3671	80	30	last	last	ADJ
fnp-3671	80	31	visit	visit	NOUN
fnp-3671	80	32	could	could	AUX
fnp-3671	80	33	also	also	ADV
fnp-3671	80	34	be	be	AUX
fnp-3671	80	35	possibly	possibly	ADV
fnp-3671	80	36	associated	associate	VERB
fnp-3671	80	37	with	with	ADP
fnp-3671	80	38	resilience	resilience	NOUN
fnp-3671	80	39	to	to	ADP
fnp-3671	80	40	clinical	clinical	ADJ
fnp-3671	80	41	expression	expression	NOUN
fnp-3671	80	42	of	of	ADP
fnp-3671	80	43	ad	ad	NOUN
fnp-3671	80	44	severe	severe	ADJ
fnp-3671	80	45	pathology	pathology	NOUN
fnp-3671	80	46	.	.	PUNCT
fnp-3671	81	1	pharmacological	pharmacological	ADJ
fnp-3671	81	2	approaches	approach	NOUN
fnp-3671	81	3	that	that	PRON
fnp-3671	81	4	mimic	mimic	VERB
fnp-3671	81	5	the	the	DET
fnp-3671	81	6	effects	effect	NOUN
fnp-3671	81	7	of	of	ADP
fnp-3671	81	8	nicotine	nicotine	NOUN
fnp-3671	81	9	may	may	AUX
fnp-3671	81	10	be	be	AUX
fnp-3671	81	11	useful	useful	ADJ
fnp-3671	81	12	in	in	ADP
fnp-3671	81	13	amelioration	amelioration	NOUN
fnp-3671	81	14	of	of	ADP
fnp-3671	81	15	ad	ad	NOUN
fnp-3671	81	16	symptoms	symptom	NOUN
fnp-3671	81	17	.	.	PUNCT
fnp-3671	81	18	  	  	SPACE
fnp-3671	82	1	abstract	abstract	ADJ
fnp-3671	82	2	7	7	NUM
fnp-3671	82	3	free	free	ADJ
fnp-3671	82	4	neuropathol	neuropathol	NOUN
fnp-3671	82	5	2:29:10	2:29:10	NUM
fnp-3671	82	6	linking	link	VERB
fnp-3671	82	7	iron	iron	NOUN
fnp-3671	82	8	homeostasis	homeostasis	NOUN
fnp-3671	82	9	to	to	ADP
fnp-3671	82	10	vulnerability	vulnerability	NOUN
fnp-3671	82	11	patterns	pattern	NOUN
fnp-3671	82	12	in	in	ADP
fnp-3671	82	13	progressive	progressive	ADJ
fnp-3671	82	14	supranuclear	supranuclear	ADJ
fnp-3671	82	15	palsy	palsy	ADJ
fnp-3671	82	16	seojin	seojin	NOUN
fnp-3671	82	17	lee1	lee1	PROPN
fnp-3671	82	18	,	,	PUNCT
fnp-3671	82	19	ivan	ivan	PROPN
fnp-3671	82	20	martinez	martinez	PROPN
fnp-3671	82	21	-	-	PUNCT
fnp-3671	82	22	valbuena1	valbuena1	PROPN
fnp-3671	82	23	,	,	PUNCT
fnp-3671	82	24	suganthini	suganthini	NOUN
fnp-3671	82	25	ilaalagan1,3	ilaalagan1,3	PROPN
fnp-3671	82	26	,	,	PUNCT
fnp-3671	82	27	naomi	naomi	NOUN
fnp-3671	82	28	p.	p.	PROPN
fnp-3671	83	1	visanji2,4	visanji2,4	PROPN
fnp-3671	83	2	,	,	PUNCT
fnp-3671	83	3	gabor	gabor	PROPN
fnp-3671	83	4	g.	g.	PROPN
fnp-3671	83	5	kovacs1,2,3,4	kovacs1,2,3,4	PROPN
fnp-3671	83	6	1	1	NUM
fnp-3671	83	7	tanz	tanz	PROPN
fnp-3671	83	8	centre	centre	NOUN
fnp-3671	83	9	for	for	ADP
fnp-3671	83	10	research	research	NOUN
fnp-3671	83	11	in	in	ADP
fnp-3671	83	12	neurodegenerative	neurodegenerative	ADJ
fnp-3671	83	13	disease	disease	NOUN
fnp-3671	83	14	,	,	PUNCT
fnp-3671	83	15	university	university	PROPN
fnp-3671	83	16	of	of	ADP
fnp-3671	83	17	toronto	toronto	PROPN
fnp-3671	83	18	,	,	PUNCT
fnp-3671	83	19	toronto	toronto	PROPN
fnp-3671	83	20	,	,	PUNCT
fnp-3671	83	21	ontario	ontario	PROPN
fnp-3671	83	22	,	,	PUNCT
fnp-3671	83	23	canada	canada	PROPN
fnp-3671	83	24	2	2	NUM
fnp-3671	83	25	department	department	NOUN
fnp-3671	83	26	of	of	ADP
fnp-3671	83	27	laboratory	laboratory	NOUN
fnp-3671	83	28	medicine	medicine	NOUN
fnp-3671	83	29	and	and	CCONJ
fnp-3671	83	30	pathobiology	pathobiology	NOUN
fnp-3671	83	31	and	and	CCONJ
fnp-3671	83	32	department	department	NOUN
fnp-3671	83	33	of	of	ADP
fnp-3671	83	34	medicine	medicine	NOUN
fnp-3671	83	35	,	,	PUNCT
fnp-3671	83	36	university	university	PROPN
fnp-3671	83	37	of	of	ADP
fnp-3671	83	38	toronto	toronto	PROPN
fnp-3671	83	39	,	,	PUNCT
fnp-3671	83	40	toronto	toronto	PROPN
fnp-3671	83	41	,	,	PUNCT
fnp-3671	83	42	ontario	ontario	PROPN
fnp-3671	83	43	,	,	PUNCT
fnp-3671	83	44	canada	canada	PROPN
fnp-3671	83	45	3	3	NUM
fnp-3671	83	46	laboratory	laboratory	NOUN
fnp-3671	83	47	medicine	medicine	NOUN
fnp-3671	83	48	program	program	PROPN
fnp-3671	83	49	&	&	CCONJ
fnp-3671	83	50	krembil	krembil	PROPN
fnp-3671	83	51	brain	brain	PROPN
fnp-3671	83	52	institute	institute	PROPN
fnp-3671	83	53	,	,	PUNCT
fnp-3671	83	54	university	university	NOUN
fnp-3671	83	55	health	health	NOUN
fnp-3671	83	56	network	network	NOUN
fnp-3671	83	57	,	,	PUNCT
fnp-3671	83	58	toronto	toronto	PROPN
fnp-3671	83	59	,	,	PUNCT
fnp-3671	83	60	ontario	ontario	PROPN
fnp-3671	83	61	,	,	PUNCT
fnp-3671	83	62	canada	canada	PROPN
fnp-3671	83	63	4	4	NUM
fnp-3671	83	64	edmund	edmund	PROPN
fnp-3671	83	65	j.	j.	PROPN
fnp-3671	83	66	safra	safra	PROPN
fnp-3671	83	67	program	program	PROPN
fnp-3671	83	68	in	in	ADP
fnp-3671	83	69	parkinson	parkinson	NOUN
fnp-3671	83	70	’s	’s	PART
fnp-3671	83	71	disease	disease	NOUN
fnp-3671	83	72	and	and	CCONJ
fnp-3671	83	73	rossy	rossy	PROPN
fnp-3671	83	74	program	program	PROPN
fnp-3671	83	75	in	in	ADP
fnp-3671	83	76	progressive	progressive	ADJ
fnp-3671	83	77	supranuclear	supranuclear	ADJ
fnp-3671	83	78	palsy	palsy	ADJ
fnp-3671	83	79	,	,	PUNCT
fnp-3671	83	80	toronto	toronto	PROPN
fnp-3671	83	81	western	western	ADJ
fnp-3671	83	82	hospital	hospital	PROPN
fnp-3671	83	83	,	,	PUNCT
fnp-3671	83	84	toronto	toronto	PROPN
fnp-3671	83	85	,	,	PUNCT
fnp-3671	83	86	ontario	ontario	PROPN
fnp-3671	83	87	,	,	PUNCT
fnp-3671	83	88	canada	canada	PROPN
fnp-3671	83	89	progressive	progressive	ADJ
fnp-3671	83	90	supranuclear	supranuclear	ADJ
fnp-3671	83	91	palsy	palsy	ADJ
fnp-3671	83	92	(	(	PUNCT
fnp-3671	83	93	psp	psp	NOUN
fnp-3671	83	94	)	)	PUNCT
fnp-3671	83	95	is	be	AUX
fnp-3671	83	96	a	a	DET
fnp-3671	83	97	4	4	NUM
fnp-3671	83	98	-	-	PUNCT
fnp-3671	83	99	repeat	repeat	NOUN
fnp-3671	83	100	tauopathy	tauopathy	NOUN
fnp-3671	83	101	in	in	ADP
fnp-3671	83	102	which	which	PRON
fnp-3671	83	103	pathology	pathology	NOUN
fnp-3671	83	104	starts	start	VERB
fnp-3671	83	105	in	in	ADP
fnp-3671	83	106	select	select	ADJ
fnp-3671	83	107	subcortical	subcortical	ADJ
fnp-3671	83	108	areas	area	NOUN
fnp-3671	83	109	including	include	VERB
fnp-3671	83	110	the	the	DET
fnp-3671	83	111	globus	globus	ADJ
fnp-3671	83	112	pallidus	pallidus	NOUN
fnp-3671	83	113	(	(	PUNCT
fnp-3671	83	114	gp	gp	NOUN
fnp-3671	83	115	)	)	PUNCT
fnp-3671	83	116	and	and	CCONJ
fnp-3671	83	117	the	the	DET
fnp-3671	83	118	substantia	substantia	NOUN
fnp-3671	83	119	nigra	nigra	NOUN
fnp-3671	83	120	(	(	PUNCT
fnp-3671	83	121	sn	sn	PROPN
fnp-3671	83	122	)	)	PUNCT
fnp-3671	83	123	,	,	PUNCT
fnp-3671	83	124	regions	region	NOUN
fnp-3671	83	125	also	also	ADV
fnp-3671	83	126	associated	associate	VERB
fnp-3671	83	127	with	with	ADP
fnp-3671	83	128	age	age	NOUN
fnp-3671	83	129	-	-	PUNCT
fnp-3671	83	130	related	relate	VERB
fnp-3671	83	131	iron	iron	NOUN
fnp-3671	83	132	accumulation	accumulation	NOUN
fnp-3671	83	133	.	.	PUNCT
fnp-3671	84	1	toxic	toxic	ADJ
fnp-3671	84	2	iron	iron	NOUN
fnp-3671	84	3	burden	burden	NOUN
fnp-3671	84	4	in	in	ADP
fnp-3671	84	5	these	these	DET
fnp-3671	84	6	regions	region	NOUN
fnp-3671	84	7	of	of	ADP
fnp-3671	84	8	psp	psp	NOUN
fnp-3671	84	9	brains	brain	NOUN
fnp-3671	84	10	have	have	AUX
fnp-3671	84	11	been	be	AUX
fnp-3671	84	12	examined	examine	VERB
fnp-3671	84	13	but	but	CCONJ
fnp-3671	84	14	given	give	VERB
fnp-3671	84	15	the	the	DET
fnp-3671	84	16	differences	difference	NOUN
fnp-3671	84	17	in	in	ADP
fnp-3671	84	18	cellular	cellular	ADJ
fnp-3671	84	19	iron	iron	NOUN
fnp-3671	84	20	homeostasis	homeostasis	NOUN
fnp-3671	84	21	across	across	ADP
fnp-3671	84	22	cell	cell	NOUN
fnp-3671	84	23	types	type	NOUN
fnp-3671	84	24	and	and	CCONJ
fnp-3671	84	25	the	the	DET
fnp-3671	84	26	heterogeneity	heterogeneity	NOUN
fnp-3671	84	27	in	in	ADP
fnp-3671	84	28	psp	psp	PROPN
fnp-3671	84	29	tau	tau	PROPN
fnp-3671	84	30	cytopathology	cytopathology	NOUN
fnp-3671	84	31	,	,	PUNCT
fnp-3671	84	32	we	we	PRON
fnp-3671	84	33	aim	aim	VERB
fnp-3671	84	34	to	to	PART
fnp-3671	84	35	examine	examine	VERB
fnp-3671	84	36	the	the	DET
fnp-3671	84	37	possible	possible	ADJ
fnp-3671	84	38	role	role	NOUN
fnp-3671	84	39	of	of	ADP
fnp-3671	84	40	iron	iron	NOUN
fnp-3671	84	41	accumulation	accumulation	NOUN
fnp-3671	84	42	on	on	ADP
fnp-3671	84	43	the	the	DET
fnp-3671	84	44	cellular	cellular	ADJ
fnp-3671	84	45	selective	selective	ADJ
fnp-3671	84	46	vulnerability	vulnerability	NOUN
fnp-3671	84	47	of	of	ADP
fnp-3671	84	48	tau	tau	PROPN
fnp-3671	84	49	pathology	pathology	NOUN
fnp-3671	84	50	in	in	ADP
fnp-3671	84	51	the	the	DET
fnp-3671	84	52	vulnerable	vulnerable	ADJ
fnp-3671	84	53	anatomical	anatomical	ADJ
fnp-3671	84	54	regions	region	NOUN
fnp-3671	84	55	of	of	ADP
fnp-3671	84	56	psp	psp	NOUN
fnp-3671	84	57	brains	brain	NOUN
fnp-3671	84	58	.	.	PUNCT
fnp-3671	85	1	using	use	VERB
fnp-3671	85	2	human	human	ADJ
fnp-3671	85	3	post	post	ADJ
fnp-3671	85	4	-	-	ADJ
fnp-3671	85	5	mortem	mortem	ADJ
fnp-3671	85	6	brain	brain	NOUN
fnp-3671	85	7	tissue	tissue	NOUN
fnp-3671	85	8	of	of	ADP
fnp-3671	85	9	the	the	DET
fnp-3671	85	10	early	early	ADV
fnp-3671	85	11	-	-	PUNCT
fnp-3671	85	12	affected	affect	VERB
fnp-3671	85	13	psp	psp	NOUN
fnp-3671	85	14	brain	brain	NOUN
fnp-3671	85	15	regions	region	NOUN
fnp-3671	85	16	(	(	PUNCT
fnp-3671	85	17	gp	gp	NOUN
fnp-3671	85	18	,	,	PUNCT
fnp-3671	85	19	sn	sn	PROPN
fnp-3671	85	20	,	,	PUNCT
fnp-3671	85	21	and	and	CCONJ
fnp-3671	85	22	putamen	putaman	NOUN
fnp-3671	85	23	)	)	PUNCT
fnp-3671	85	24	,	,	PUNCT
fnp-3671	85	25	we	we	PRON
fnp-3671	85	26	visualized	visualize	VERB
fnp-3671	85	27	iron	iron	NOUN
fnp-3671	85	28	deposition	deposition	NOUN
fnp-3671	85	29	in	in	ADP
fnp-3671	85	30	the	the	DET
fnp-3671	85	31	neurons	neuron	NOUN
fnp-3671	85	32	,	,	PUNCT
fnp-3671	85	33	astroglia	astroglia	PROPN
fnp-3671	85	34	,	,	PUNCT
fnp-3671	85	35	oligodendrocytes	oligodendrocyte	NOUN
fnp-3671	85	36	,	,	PUNCT
fnp-3671	85	37	and	and	CCONJ
fnp-3671	85	38	microglia	microglia	NOUN
fnp-3671	85	39	using	use	VERB
fnp-3671	85	40	a	a	DET
fnp-3671	85	41	combination	combination	NOUN
fnp-3671	85	42	of	of	ADP
fnp-3671	85	43	dab	dab	NOUN
fnp-3671	85	44	-	-	PUNCT
fnp-3671	85	45	enhanced	enhance	VERB
fnp-3671	85	46	perl	perl	NOUN
fnp-3671	85	47	’s	’s	PART
fnp-3671	85	48	(	(	PUNCT
fnp-3671	85	49	ferric	ferric	NOUN
fnp-3671	85	50	)	)	PUNCT
fnp-3671	85	51	and	and	CCONJ
fnp-3671	85	52	turnbull	turnbull	PROPN
fnp-3671	85	53	(	(	PUNCT
fnp-3671	85	54	ferrous	ferrous	ADJ
fnp-3671	85	55	)	)	PUNCT
fnp-3671	85	56	iron	iron	NOUN
fnp-3671	85	57	staining	stain	VERB
fnp-3671	85	58	with	with	ADP
fnp-3671	85	59	immunohistochemistry	immunohistochemistry	NOUN
fnp-3671	85	60	of	of	ADP
fnp-3671	85	61	cell	cell	NOUN
fnp-3671	85	62	type	type	NOUN
fnp-3671	85	63	-	-	PUNCT
fnp-3671	85	64	specific	specific	ADJ
fnp-3671	85	65	markers	marker	NOUN
fnp-3671	85	66	.	.	PUNCT
fnp-3671	86	1	iron	iron	NOUN
fnp-3671	86	2	deposition	deposition	NOUN
fnp-3671	86	3	was	be	AUX
fnp-3671	86	4	also	also	ADV
fnp-3671	86	5	examined	examine	VERB
fnp-3671	86	6	in	in	ADP
fnp-3671	86	7	relation	relation	NOUN
fnp-3671	86	8	to	to	ADP
fnp-3671	86	9	their	their	PRON
fnp-3671	86	10	tau	tau	PROPN
fnp-3671	86	11	cytopathologies	cytopathologie	NOUN
fnp-3671	86	12	using	use	VERB
fnp-3671	86	13	at8	at8	PROPN
fnp-3671	86	14	-	-	PUNCT
fnp-3671	86	15	immunohistochemistry	immunohistochemistry	NOUN
fnp-3671	86	16	.	.	PUNCT
fnp-3671	87	1	in	in	ADP
fnp-3671	87	2	all	all	DET
fnp-3671	87	3	three	three	NUM
fnp-3671	87	4	regions	region	NOUN
fnp-3671	87	5	,	,	PUNCT
fnp-3671	87	6	astrocytes	astrocyte	NOUN
fnp-3671	87	7	and	and	CCONJ
fnp-3671	87	8	microglia	microglia	NOUN
fnp-3671	87	9	were	be	AUX
fnp-3671	87	10	seen	see	VERB
fnp-3671	87	11	to	to	PART
fnp-3671	87	12	predominantly	predominantly	ADV
fnp-3671	87	13	accumulate	accumulate	VERB
fnp-3671	87	14	both	both	DET
fnp-3671	87	15	species	specie	NOUN
fnp-3671	87	16	of	of	ADP
fnp-3671	87	17	iron	iron	NOUN
fnp-3671	87	18	.	.	PUNCT
fnp-3671	88	1	moreover	moreover	ADV
fnp-3671	88	2	,	,	PUNCT
fnp-3671	88	3	tau	tau	ADJ
fnp-3671	88	4	-	-	PUNCT
fnp-3671	88	5	positive	positive	ADJ
fnp-3671	88	6	astrocytes	astrocyte	NOUN
fnp-3671	88	7	showed	show	VERB
fnp-3671	88	8	the	the	DET
fnp-3671	88	9	highest	high	ADJ
fnp-3671	88	10	frequency	frequency	NOUN
fnp-3671	88	11	of	of	ADP
fnp-3671	88	12	cellular	cellular	ADJ
fnp-3671	88	13	iron	iron	NOUN
fnp-3671	88	14	deposition	deposition	NOUN
fnp-3671	88	15	compared	compare	VERB
fnp-3671	88	16	to	to	ADP
fnp-3671	88	17	neurofibrillary	neurofibrillary	ADJ
fnp-3671	88	18	tangles	tangle	NOUN
fnp-3671	88	19	and	and	CCONJ
fnp-3671	88	20	oligodendroglial	oligodendroglial	ADJ
fnp-3671	88	21	coiled	coil	VERB
fnp-3671	88	22	bodies	body	NOUN
fnp-3671	88	23	.	.	PUNCT
fnp-3671	89	1	on	on	ADP
fnp-3671	89	2	the	the	DET
fnp-3671	89	3	other	other	ADJ
fnp-3671	89	4	hand	hand	NOUN
fnp-3671	89	5	,	,	PUNCT
fnp-3671	89	6	association	association	NOUN
fnp-3671	89	7	of	of	ADP
fnp-3671	89	8	iron	iron	NOUN
fnp-3671	89	9	burden	burden	NOUN
fnp-3671	89	10	with	with	ADP
fnp-3671	89	11	different	different	ADJ
fnp-3671	89	12	cellular	cellular	ADJ
fnp-3671	89	13	tau	tau	PROPN
fnp-3671	89	14	pathologies	pathology	NOUN
fnp-3671	89	15	was	be	AUX
fnp-3671	89	16	species	specie	NOUN
fnp-3671	89	17	-	-	PUNCT
fnp-3671	89	18	specific	specific	ADJ
fnp-3671	89	19	in	in	ADP
fnp-3671	89	20	the	the	DET
fnp-3671	89	21	same	same	ADJ
fnp-3671	89	22	regions	region	NOUN
fnp-3671	89	23	,	,	PUNCT
fnp-3671	89	24	suggesting	suggest	VERB
fnp-3671	89	25	iron	iron	NOUN
fnp-3671	89	26	functions	function	NOUN
fnp-3671	89	27	in	in	ADP
fnp-3671	89	28	psp	psp	PROPN
fnp-3671	89	29	tau	tau	PROPN
fnp-3671	89	30	cytopathology	cytopathology	NOUN
fnp-3671	89	31	may	may	AUX
fnp-3671	89	32	be	be	AUX
fnp-3671	89	33	distinct	distinct	ADJ
fnp-3671	89	34	by	by	ADP
fnp-3671	89	35	species	specie	NOUN
fnp-3671	89	36	.	.	PUNCT
fnp-3671	90	1	our	our	PRON
fnp-3671	90	2	mapping	mapping	NOUN
fnp-3671	90	3	of	of	ADP
fnp-3671	90	4	cellular	cellular	ADJ
fnp-3671	90	5	iron	iron	NOUN
fnp-3671	90	6	burden	burden	NOUN
fnp-3671	90	7	in	in	ADP
fnp-3671	90	8	relation	relation	NOUN
fnp-3671	90	9	to	to	ADP
fnp-3671	90	10	pathology	pathology	NOUN
fnp-3671	90	11	in	in	ADP
fnp-3671	90	12	psp	psp	NOUN
fnp-3671	90	13	brains	brain	NOUN
fnp-3671	90	14	suggests	suggest	VERB
fnp-3671	90	15	a	a	DET
fnp-3671	90	16	selective	selective	ADJ
fnp-3671	90	17	cellular	cellular	ADJ
fnp-3671	90	18	vulnerability	vulnerability	NOUN
fnp-3671	90	19	to	to	PART
fnp-3671	90	20	iron	iron	VERB
fnp-3671	90	21	deposition	deposition	NOUN
fnp-3671	90	22	in	in	ADP
fnp-3671	90	23	diseased	diseased	ADJ
fnp-3671	90	24	brains	brain	NOUN
fnp-3671	90	25	,	,	PUNCT
fnp-3671	90	26	and	and	CCONJ
fnp-3671	90	27	further	far	ADV
fnp-3671	90	28	supports	support	VERB
fnp-3671	90	29	the	the	DET
fnp-3671	90	30	role	role	NOUN
fnp-3671	90	31	of	of	ADP
fnp-3671	90	32	pathological	pathological	ADJ
fnp-3671	90	33	iron	iron	NOUN
fnp-3671	90	34	in	in	ADP
fnp-3671	90	35	the	the	DET
fnp-3671	90	36	early	early	ADJ
fnp-3671	90	37	pathogenesis	pathogenesis	NOUN
fnp-3671	90	38	of	of	ADP
fnp-3671	90	39	psp	psp	NOUN
fnp-3671	90	40	.	.	PUNCT
fnp-3671	90	41	  	  	SPACE
fnp-3671	91	1	abstract	abstract	ADJ
fnp-3671	91	2	8	8	NUM
fnp-3671	91	3	free	free	ADJ
fnp-3671	91	4	neuropathol	neuropathol	NOUN
fnp-3671	91	5	2:29:11	2:29:11	NUM
fnp-3671	91	6	friedreich	friedreich	NOUN
fnp-3671	91	7	cardiomyopathy	cardiomyopathy	ADJ
fnp-3671	91	8	is	be	AUX
fnp-3671	91	9	a	a	DET
fnp-3671	91	10	secondary	secondary	ADJ
fnp-3671	91	11	desminopathy	desminopathy	ADJ
fnp-3671	91	12	arnulf	arnulf	NOUN
fnp-3671	91	13	h.	h.	PROPN
fnp-3671	91	14	koeppen1,6	koeppen1,6	PROPN
fnp-3671	91	15	,	,	PUNCT
fnp-3671	91	16	rahman	rahman	PROPN
fnp-3671	91	17	f.	f.	PROPN
fnp-3671	91	18	rafique1	rafique1	PROPN
fnp-3671	91	19	,	,	PUNCT
fnp-3671	91	20	joseph	joseph	PROPN
fnp-3671	91	21	e.	e.	PROPN
fnp-3671	91	22	mazurkiewicz2	mazurkiewicz2	PROPN
fnp-3671	91	23	,	,	PUNCT
fnp-3671	91	24	steven	steven	PROPN
fnp-3671	91	25	pelech3,4	pelech3,4	PROPN
fnp-3671	91	26	,	,	PUNCT
fnp-3671	91	27	catherine	catherine	PROPN
fnp-3671	91	28	sutter3	sutter3	PROPN
fnp-3671	91	29	,	,	PUNCT
fnp-3671	91	30	qishan	qishan	PROPN
fnp-3671	91	31	lin5	lin5	PROPN
fnp-3671	91	32	,	,	PUNCT
fnp-3671	91	33	jiang	jiang	PROPN
fnp-3671	91	34	qian6	qian6	PROPN
fnp-3671	91	35	1	1	NUM
fnp-3671	91	36	research	research	NOUN
fnp-3671	91	37	service	service	NOUN
fnp-3671	91	38	,	,	PUNCT
fnp-3671	91	39	veterans	veterans	PROPN
fnp-3671	91	40	affairs	affairs	PROPN
fnp-3671	91	41	medical	medical	ADJ
fnp-3671	91	42	center	center	PROPN
fnp-3671	91	43	,	,	PUNCT
fnp-3671	91	44	albany	albany	PROPN
fnp-3671	91	45	,	,	PUNCT
fnp-3671	91	46	new	new	PROPN
fnp-3671	91	47	york	york	PROPN
fnp-3671	91	48	,	,	PUNCT
fnp-3671	91	49	usa	usa	PROPN
fnp-3671	91	50	2	2	NUM
fnp-3671	91	51	department	department	NOUN
fnp-3671	91	52	of	of	ADP
fnp-3671	91	53	neuroscience	neuroscience	NOUN
fnp-3671	91	54	and	and	CCONJ
fnp-3671	91	55	experimental	experimental	ADJ
fnp-3671	91	56	therapeutics	therapeutic	NOUN
fnp-3671	91	57	,	,	PUNCT
fnp-3671	91	58	albany	albany	PROPN
fnp-3671	91	59	medical	medical	PROPN
fnp-3671	91	60	college	college	PROPN
fnp-3671	91	61	,	,	PUNCT
fnp-3671	91	62	albany	albany	PROPN
fnp-3671	91	63	,	,	PUNCT
fnp-3671	91	64	new	new	PROPN
fnp-3671	91	65	york	york	PROPN
fnp-3671	91	66	,	,	PUNCT
fnp-3671	91	67	usa	usa	PROPN
fnp-3671	91	68	3	3	NUM
fnp-3671	91	69	kinexus	kinexus	NOUN
fnp-3671	91	70	bioinformatics	bioinformatics	NOUN
fnp-3671	91	71	corporation	corporation	NOUN
fnp-3671	91	72	,	,	PUNCT
fnp-3671	91	73	vancouver	vancouver	PROPN
fnp-3671	91	74	,	,	PUNCT
fnp-3671	91	75	british	british	PROPN
fnp-3671	91	76	columbia	columbia	PROPN
fnp-3671	91	77	,	,	PUNCT
fnp-3671	91	78	canada	canada	PROPN
fnp-3671	91	79	4	4	NUM
fnp-3671	91	80	division	division	NOUN
fnp-3671	91	81	of	of	ADP
fnp-3671	91	82	neurology	neurology	NOUN
fnp-3671	91	83	,	,	PUNCT
fnp-3671	91	84	department	department	NOUN
fnp-3671	91	85	of	of	ADP
fnp-3671	91	86	medicine	medicine	NOUN
fnp-3671	91	87	,	,	PUNCT
fnp-3671	91	88	university	university	NOUN
fnp-3671	91	89	of	of	ADP
fnp-3671	91	90	british	british	PROPN
fnp-3671	91	91	columbia	columbia	PROPN
fnp-3671	91	92	,	,	PUNCT
fnp-3671	91	93	vancouver	vancouver	PROPN
fnp-3671	91	94	,	,	PUNCT
fnp-3671	91	95	british	british	PROPN
fnp-3671	91	96	columbia	columbia	PROPN
fnp-3671	91	97	,	,	PUNCT
fnp-3671	91	98	canada	canada	PROPN
fnp-3671	91	99	5	5	NUM
fnp-3671	91	100	rna	rna	PROPN
fnp-3671	91	101	epitranscriptomics	epitranscriptomic	NOUN
fnp-3671	91	102	&	&	CCONJ
fnp-3671	91	103	proteomics	proteomic	NOUN
fnp-3671	91	104	resource	resource	NOUN
fnp-3671	91	105	,	,	PUNCT
fnp-3671	91	106	university	university	NOUN
fnp-3671	91	107	at	at	ADP
fnp-3671	91	108	albany	albany	PROPN
fnp-3671	91	109	,	,	PUNCT
fnp-3671	91	110	albany	albany	PROPN
fnp-3671	91	111	,	,	PUNCT
fnp-3671	91	112	new	new	PROPN
fnp-3671	91	113	york	york	PROPN
fnp-3671	91	114	,	,	PUNCT
fnp-3671	91	115	usa	usa	PROPN
fnp-3671	91	116	6	6	NUM
fnp-3671	91	117	department	department	NOUN
fnp-3671	91	118	of	of	ADP
fnp-3671	91	119	pathology	pathology	PROPN
fnp-3671	91	120	,	,	PUNCT
fnp-3671	91	121	albany	albany	PROPN
fnp-3671	91	122	medical	medical	PROPN
fnp-3671	91	123	college	college	PROPN
fnp-3671	91	124	,	,	PUNCT
fnp-3671	91	125	albany	albany	PROPN
fnp-3671	91	126	,	,	PUNCT
fnp-3671	91	127	new	new	PROPN
fnp-3671	91	128	york	york	PROPN
fnp-3671	91	129	,	,	PUNCT
fnp-3671	91	130	usa	usa	PROPN
fnp-3671	91	131	hypertrophic	hypertrophic	PROPN
fnp-3671	91	132	cardiomyopathy	cardiomyopathy	ADJ
fnp-3671	91	133	with	with	ADP
fnp-3671	91	134	or	or	CCONJ
fnp-3671	91	135	without	without	ADP
fnp-3671	91	136	arrhythmia	arrhythmia	NOUN
fnp-3671	91	137	is	be	AUX
fnp-3671	91	138	the	the	DET
fnp-3671	91	139	predominant	predominant	ADJ
fnp-3671	91	140	cause	cause	NOUN
fnp-3671	91	141	of	of	ADP
fnp-3671	91	142	death	death	NOUN
fnp-3671	91	143	in	in	ADP
fnp-3671	91	144	friedreich	friedreich	NOUN
fnp-3671	91	145	ataxia	ataxia	NOUN
fnp-3671	91	146	(	(	PUNCT
fnp-3671	91	147	fa	fa	NOUN
fnp-3671	91	148	)	)	PUNCT
fnp-3671	91	149	.	.	PUNCT
fnp-3671	92	1	the	the	DET
fnp-3671	92	2	clinical	clinical	ADJ
fnp-3671	92	3	and	and	CCONJ
fnp-3671	92	4	pathological	pathological	ADJ
fnp-3671	92	5	phenotypes	phenotype	NOUN
fnp-3671	92	6	of	of	ADP
fnp-3671	92	7	fa	fa	PROPN
fnp-3671	92	8	are	be	AUX
fnp-3671	92	9	diverse	diverse	ADJ
fnp-3671	92	10	.	.	PUNCT
fnp-3671	93	1	the	the	DET
fnp-3671	93	2	pathogenesis	pathogenesis	NOUN
fnp-3671	93	3	of	of	ADP
fnp-3671	93	4	the	the	DET
fnp-3671	93	5	fa	fa	NOUN
fnp-3671	93	6	-	-	PUNCT
fnp-3671	93	7	related	relate	VERB
fnp-3671	93	8	lesions	lesion	NOUN
fnp-3671	93	9	in	in	ADP
fnp-3671	93	10	the	the	DET
fnp-3671	93	11	central	central	ADJ
fnp-3671	93	12	and	and	CCONJ
fnp-3671	93	13	peripheral	peripheral	ADJ
fnp-3671	93	14	nervous	nervous	ADJ
fnp-3671	93	15	systems	system	NOUN
fnp-3671	93	16	,	,	PUNCT
fnp-3671	93	17	heart	heart	NOUN
fnp-3671	93	18	,	,	PUNCT
fnp-3671	93	19	skeleton	skeleton	NOUN
fnp-3671	93	20	,	,	PUNCT
fnp-3671	93	21	and	and	CCONJ
fnp-3671	93	22	endocrine	endocrine	ADJ
fnp-3671	93	23	pancreas	pancreas	NOUN
fnp-3671	93	24	is	be	AUX
fnp-3671	93	25	incompletely	incompletely	ADV
fnp-3671	93	26	understood	understand	VERB
fnp-3671	93	27	.	.	PUNCT
fnp-3671	94	1	the	the	DET
fnp-3671	94	2	hypothesis	hypothesis	NOUN
fnp-3671	94	3	in	in	ADP
fnp-3671	94	4	this	this	DET
fnp-3671	94	5	research	research	NOUN
fnp-3671	94	6	is	be	AUX
fnp-3671	94	7	that	that	SCONJ
fnp-3671	94	8	frataxin	frataxin	NOUN
fnp-3671	94	9	deficiency	deficiency	NOUN
fnp-3671	94	10	affects	affect	VERB
fnp-3671	94	11	the	the	DET
fnp-3671	94	12	cellular	cellular	ADJ
fnp-3671	94	13	proteome	proteome	NOUN
fnp-3671	94	14	in	in	ADP
fnp-3671	94	15	downstream	downstream	ADJ
fnp-3671	94	16	mechanisms	mechanism	NOUN
fnp-3671	94	17	.	.	PUNCT
fnp-3671	95	1	antibody	antibody	NOUN
fnp-3671	95	2	microarrays	microarray	NOUN
fnp-3671	95	3	of	of	ADP
fnp-3671	95	4	pooled	pool	VERB
fnp-3671	95	5	fa	fa	NOUN
fnp-3671	95	6	heart	heart	NOUN
fnp-3671	95	7	lysates	lysate	NOUN
fnp-3671	95	8	showed	show	VERB
fnp-3671	95	9	upregulation	upregulation	NOUN
fnp-3671	95	10	in	in	ADP
fnp-3671	95	11	several	several	ADJ
fnp-3671	95	12	proteins	protein	NOUN
fnp-3671	95	13	,	,	PUNCT
fnp-3671	95	14	including	include	VERB
fnp-3671	95	15	alpha	alpha	NOUN
fnp-3671	95	16	b	b	PROPN
fnp-3671	95	17	crystallin	crystallin	NOUN
fnp-3671	95	18	,	,	PUNCT
fnp-3671	95	19	a	a	DET
fnp-3671	95	20	desmin	desmin	ADJ
fnp-3671	95	21	chaperone	chaperone	NOUN
fnp-3671	95	22	.	.	PUNCT
fnp-3671	96	1	western	western	ADJ
fnp-3671	96	2	blots	blot	NOUN
fnp-3671	96	3	of	of	ADP
fnp-3671	96	4	individual	individual	ADJ
fnp-3671	96	5	and	and	CCONJ
fnp-3671	96	6	pooled	pool	VERB
fnp-3671	96	7	heart	heart	NOUN
fnp-3671	96	8	lysates	lysate	NOUN
fnp-3671	96	9	revealed	reveal	VERB
fnp-3671	96	10	a	a	DET
fnp-3671	96	11	prominent	prominent	ADJ
fnp-3671	96	12	extra	extra	ADJ
fnp-3671	96	13	desmin	desmin	ADJ
fnp-3671	96	14	band	band	NOUN
fnp-3671	96	15	at	at	ADP
fnp-3671	96	16	47	47	NUM
fnp-3671	96	17	kda	kda	NOUN
fnp-3671	96	18	that	that	PRON
fnp-3671	96	19	was	be	AUX
fnp-3671	96	20	absent	absent	ADJ
fnp-3671	96	21	or	or	CCONJ
fnp-3671	96	22	under	under	ADV
fnp-3671	96	23	-	-	PUNCT
fnp-3671	96	24	expressed	express	VERB
fnp-3671	96	25	in	in	ADP
fnp-3671	96	26	control	control	NOUN
fnp-3671	96	27	samples	sample	NOUN
fnp-3671	96	28	.	.	PUNCT
fnp-3671	97	1	mass	mass	PROPN
fnp-3671	97	2	spectrometry	spectrometry	NOUN
fnp-3671	97	3	confirmed	confirm	VERB
fnp-3671	97	4	the	the	DET
fnp-3671	97	5	origin	origin	NOUN
fnp-3671	97	6	of	of	ADP
fnp-3671	97	7	this	this	DET
fnp-3671	97	8	band	band	NOUN
fnp-3671	97	9	from	from	ADP
fnp-3671	97	10	canonical	canonical	ADJ
fnp-3671	97	11	desmin	desmin	NOUN
fnp-3671	97	12	(	(	PUNCT
fnp-3671	97	13	53	53	NUM
fnp-3671	97	14	kda	kda	NOUN
fnp-3671	97	15	)	)	PUNCT
fnp-3671	97	16	.	.	PUNCT
fnp-3671	98	1	co	co	NOUN
fnp-3671	98	2	-	-	NOUN
fnp-3671	98	3	immunoprecipitation	immunoprecipitation	NOUN
fnp-3671	98	4	of	of	ADP
fnp-3671	98	5	fa	fa	NOUN
fnp-3671	98	6	heart	heart	NOUN
fnp-3671	98	7	lysates	lysate	NOUN
fnp-3671	98	8	with	with	ADP
fnp-3671	98	9	anti	anti	ADJ
fnp-3671	98	10	-	-	ADJ
fnp-3671	98	11	desmin	desmin	ADJ
fnp-3671	98	12	,	,	PUNCT
fnp-3671	98	13	recovery	recovery	NOUN
fnp-3671	98	14	of	of	ADP
fnp-3671	98	15	the	the	DET
fnp-3671	98	16	antigen	antigen	NOUN
fnp-3671	98	17	-	-	PUNCT
fnp-3671	98	18	antibody	antibody	NOUN
fnp-3671	98	19	complex	complex	NOUN
fnp-3671	98	20	with	with	ADP
fnp-3671	98	21	protein	protein	NOUN
fnp-3671	98	22	a	a	NOUN
fnp-3671	98	23	-	-	PUNCT
fnp-3671	98	24	sepharose	sepharose	NOUN
fnp-3671	98	25	,	,	PUNCT
fnp-3671	98	26	sodium	sodium	NOUN
fnp-3671	98	27	dodecylsulfate	dodecylsulfate	VERB
fnp-3671	98	28	polyacrylamide	polyacrylamide	NOUN
fnp-3671	98	29	gel	gel	NOUN
fnp-3671	98	30	electrophoresis	electrophoresis	NOUN
fnp-3671	98	31	,	,	PUNCT
fnp-3671	98	32	and	and	CCONJ
fnp-3671	98	33	western	western	ADJ
fnp-3671	98	34	blotting	blotting	NOUN
fnp-3671	98	35	confirmed	confirm	VERB
fnp-3671	98	36	the	the	DET
fnp-3671	98	37	interaction	interaction	NOUN
fnp-3671	98	38	of	of	ADP
fnp-3671	98	39	desmin	desmin	PROPN
fnp-3671	98	40	and	and	CCONJ
fnp-3671	98	41	αb	αb	ADP
fnp-3671	98	42	crystallin	crystallin	NOUN
fnp-3671	98	43	.	.	PUNCT
fnp-3671	99	1	slide	slide	NOUN
fnp-3671	99	2	techniques	technique	NOUN
fnp-3671	99	3	,	,	PUNCT
fnp-3671	99	4	including	include	VERB
fnp-3671	99	5	immunohistochemistry	immunohistochemistry	NOUN
fnp-3671	99	6	and	and	CCONJ
fnp-3671	99	7	double	double	ADJ
fnp-3671	99	8	-	-	PUNCT
fnp-3671	99	9	label	label	NOUN
fnp-3671	99	10	immunofluorescence	immunofluorescence	NOUN
fnp-3671	99	11	,	,	PUNCT
fnp-3671	99	12	disclosed	disclose	VERB
fnp-3671	99	13	desmin	desmin	ADJ
fnp-3671	99	14	and	and	CCONJ
fnp-3671	99	15	alpha	alpha	PROPN
fnp-3671	99	16	b	b	PROPN
fnp-3671	99	17	crystallin	crystallin	PROPN
fnp-3671	99	18	aggregation	aggregation	NOUN
fnp-3671	99	19	near	near	ADP
fnp-3671	99	20	intercalated	intercalated	ADJ
fnp-3671	99	21	discs	disc	NOUN
fnp-3671	99	22	and	and	CCONJ
fnp-3671	99	23	z	z	NOUN
fnp-3671	99	24	-	-	PUNCT
fnp-3671	99	25	discs	disc	NOUN
fnp-3671	99	26	.	.	PUNCT
fnp-3671	100	1	congo	congo	PROPN
fnp-3671	100	2	red	red	PROPN
fnp-3671	100	3	fluorescence	fluorescence	PROPN
fnp-3671	100	4	microscopy	microscopy	NOUN
fnp-3671	100	5	did	do	AUX
fnp-3671	100	6	not	not	PART
fnp-3671	100	7	confirm	confirm	VERB
fnp-3671	100	8	the	the	DET
fnp-3671	100	9	formation	formation	NOUN
fnp-3671	100	10	of	of	ADP
fnp-3671	100	11	amyloid	amyloid	NOUN
fnp-3671	100	12	.	.	PUNCT
fnp-3671	101	1	we	we	PRON
fnp-3671	101	2	suggest	suggest	VERB
fnp-3671	101	3	that	that	SCONJ
fnp-3671	101	4	accumulation	accumulation	NOUN
fnp-3671	101	5	of	of	ADP
fnp-3671	101	6	a	a	DET
fnp-3671	101	7	truncated	truncated	ADJ
fnp-3671	101	8	desmin	desmin	NOUN
fnp-3671	101	9	and	and	CCONJ
fnp-3671	101	10	aggregation	aggregation	NOUN
fnp-3671	101	11	with	with	ADP
fnp-3671	101	12	αb	αb	NOUN
fnp-3671	101	13	crystallin	crystallin	PROPN
fnp-3671	101	14	cause	cause	PROPN
fnp-3671	101	15	accelerated	accelerate	VERB
fnp-3671	101	16	heart	heart	NOUN
fnp-3671	101	17	disease	disease	NOUN
fnp-3671	101	18	in	in	ADP
fnp-3671	101	19	fa	fa	PROPN
fnp-3671	101	20	.	.	PUNCT
fnp-3671	101	21	  	  	SPACE
fnp-3671	101	22	abstract	abstract	ADJ
fnp-3671	101	23	9	9	NUM
fnp-3671	101	24	free	free	ADJ
fnp-3671	101	25	neuropathol	neuropathol	NOUN
fnp-3671	101	26	2:29:12	2:29:12	NUM
fnp-3671	101	27	glial	glial	ADJ
fnp-3671	101	28	senescence	senescence	NOUN
fnp-3671	101	29	(	(	PUNCT
fnp-3671	101	30	not	not	PART
fnp-3671	101	31	tau	tau	PROPN
fnp-3671	101	32	)	)	PUNCT
fnp-3671	101	33	is	be	AUX
fnp-3671	101	34	the	the	DET
fnp-3671	101	35	driver	driver	NOUN
fnp-3671	101	36	of	of	ADP
fnp-3671	101	37	post	post	ADJ
fnp-3671	101	38	-	-	ADJ
fnp-3671	101	39	concussive	concussive	ADJ
fnp-3671	101	40	symptoms	symptom	NOUN
fnp-3671	101	41	lili	lili	PROPN
fnp-3671	101	42	-	-	PUNCT
fnp-3671	101	43	naz	naz	PROPN
fnp-3671	101	44	hazrati1,2	hazrati1,2	PROPN
fnp-3671	101	45	,	,	PUNCT
fnp-3671	101	46	nicole	nicole	NOUN
fnp-3671	101	47	schwab1,2	schwab1,2	PROPN
fnp-3671	101	48	1	1	NUM
fnp-3671	101	49	the	the	DET
fnp-3671	101	50	hospital	hospital	NOUN
fnp-3671	101	51	for	for	ADP
fnp-3671	101	52	sick	sick	ADJ
fnp-3671	101	53	children	child	NOUN
fnp-3671	101	54	,	,	PUNCT
fnp-3671	101	55	toronto	toronto	PROPN
fnp-3671	101	56	,	,	PUNCT
fnp-3671	101	57	ontario	ontario	PROPN
fnp-3671	101	58	,	,	PUNCT
fnp-3671	101	59	canada	canada	PROPN
fnp-3671	101	60	2	2	NUM
fnp-3671	101	61	department	department	NOUN
fnp-3671	101	62	of	of	ADP
fnp-3671	101	63	laboratory	laboratory	NOUN
fnp-3671	101	64	medicine	medicine	NOUN
fnp-3671	101	65	and	and	CCONJ
fnp-3671	101	66	pathobiology	pathobiology	NOUN
fnp-3671	101	67	,	,	PUNCT
fnp-3671	101	68	university	university	PROPN
fnp-3671	101	69	of	of	ADP
fnp-3671	101	70	toronto	toronto	PROPN
fnp-3671	101	71	,	,	PUNCT
fnp-3671	101	72	toronto	toronto	PROPN
fnp-3671	101	73	,	,	PUNCT
fnp-3671	101	74	ontario	ontario	PROPN
fnp-3671	101	75	,	,	PUNCT
fnp-3671	101	76	canada	canada	PROPN
fnp-3671	101	77	mild	mild	ADJ
fnp-3671	101	78	traumatic	traumatic	ADJ
fnp-3671	101	79	brain	brain	NOUN
fnp-3671	101	80	injury	injury	NOUN
fnp-3671	101	81	(	(	PUNCT
fnp-3671	101	82	mtbi	mtbi	NOUN
fnp-3671	101	83	)	)	PUNCT
fnp-3671	101	84	leads	lead	VERB
fnp-3671	101	85	to	to	ADP
fnp-3671	101	86	chronic	chronic	ADJ
fnp-3671	101	87	symptoms	symptom	NOUN
fnp-3671	101	88	in	in	ADP
fnp-3671	101	89	some	some	DET
fnp-3671	101	90	patients	patient	NOUN
fnp-3671	101	91	.	.	PUNCT
fnp-3671	102	1	pathologically	pathologically	ADV
fnp-3671	102	2	,	,	PUNCT
fnp-3671	102	3	mtbi	mtbi	PROPN
fnp-3671	102	4	is	be	AUX
fnp-3671	102	5	associated	associate	VERB
fnp-3671	102	6	with	with	ADP
fnp-3671	102	7	chronic	chronic	ADJ
fnp-3671	102	8	traumatic	traumatic	ADJ
fnp-3671	102	9	encephalopathy	encephalopathy	NOUN
fnp-3671	102	10	(	(	PUNCT
fnp-3671	102	11	cte	cte	NOUN
fnp-3671	102	12	)	)	PUNCT
fnp-3671	102	13	,	,	PUNCT
fnp-3671	102	14	a	a	DET
fnp-3671	102	15	neurodegenerative	neurodegenerative	ADJ
fnp-3671	102	16	disease	disease	NOUN
fnp-3671	102	17	characterized	characterize	VERB
fnp-3671	102	18	by	by	ADP
fnp-3671	102	19	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-3671	102	20	tau	tau	PROPN
fnp-3671	102	21	(	(	PUNCT
fnp-3671	102	22	p	p	PROPN
fnp-3671	102	23	-	-	PUNCT
fnp-3671	102	24	tau	tau	NOUN
fnp-3671	102	25	)	)	PUNCT
fnp-3671	102	26	in	in	ADP
fnp-3671	102	27	neurons	neuron	NOUN
fnp-3671	102	28	and	and	CCONJ
fnp-3671	102	29	astrocytes	astrocyte	NOUN
fnp-3671	102	30	at	at	ADP
fnp-3671	102	31	the	the	DET
fnp-3671	102	32	depths	depth	NOUN
fnp-3671	102	33	of	of	ADP
fnp-3671	102	34	cortical	cortical	ADJ
fnp-3671	102	35	sulci	sulci	NOUN
fnp-3671	102	36	.	.	PUNCT
fnp-3671	103	1	cte	cte	PROPN
fnp-3671	103	2	has	have	AUX
fnp-3671	103	3	been	be	AUX
fnp-3671	103	4	proposed	propose	VERB
fnp-3671	103	5	as	as	ADP
fnp-3671	103	6	the	the	DET
fnp-3671	103	7	driver	driver	NOUN
fnp-3671	103	8	of	of	ADP
fnp-3671	103	9	these	these	DET
fnp-3671	103	10	symptoms	symptom	NOUN
fnp-3671	103	11	,	,	PUNCT
fnp-3671	103	12	despite	despite	SCONJ
fnp-3671	103	13	many	many	ADJ
fnp-3671	103	14	patients	patient	NOUN
fnp-3671	103	15	presenting	present	VERB
fnp-3671	103	16	with	with	ADP
fnp-3671	103	17	severe	severe	ADJ
fnp-3671	103	18	symptoms	symptom	NOUN
fnp-3671	103	19	yet	yet	CCONJ
fnp-3671	103	20	minimal	minimal	ADJ
fnp-3671	103	21	pathology	pathology	NOUN
fnp-3671	103	22	.	.	PUNCT
fnp-3671	104	1	it	it	PRON
fnp-3671	104	2	is	be	AUX
fnp-3671	104	3	known	know	VERB
fnp-3671	104	4	that	that	SCONJ
fnp-3671	104	5	low	low	ADJ
fnp-3671	104	6	levels	level	NOUN
fnp-3671	104	7	of	of	ADP
fnp-3671	104	8	p	p	PROPN
fnp-3671	104	9	-	-	PUNCT
fnp-3671	104	10	tau	tau	PROPN
fnp-3671	104	11	are	be	AUX
fnp-3671	104	12	present	present	ADJ
fnp-3671	104	13	in	in	ADP
fnp-3671	104	14	cognitively	cognitively	ADV
fnp-3671	104	15	intact	intact	ADJ
fnp-3671	104	16	individuals	individual	NOUN
fnp-3671	104	17	,	,	PUNCT
fnp-3671	104	18	including	include	VERB
fnp-3671	104	19	ageing	age	VERB
fnp-3671	104	20	-	-	PUNCT
fnp-3671	104	21	related	relate	VERB
fnp-3671	104	22	tau	tau	PROPN
fnp-3671	104	23	astrogliopathy	astrogliopathy	ADJ
fnp-3671	104	24	(	(	PUNCT
fnp-3671	104	25	artag	artag	ADJ
fnp-3671	104	26	)	)	PUNCT
fnp-3671	104	27	,	,	PUNCT
fnp-3671	104	28	and	and	CCONJ
fnp-3671	104	29	that	that	SCONJ
fnp-3671	104	30	p	p	PROPN
fnp-3671	104	31	-	-	PUNCT
fnp-3671	104	32	tau	tau	PROPN
fnp-3671	104	33	accumulates	accumulate	VERB
fnp-3671	104	34	prior	prior	ADV
fnp-3671	104	35	to	to	ADP
fnp-3671	104	36	a	a	DET
fnp-3671	104	37	diagnosis	diagnosis	NOUN
fnp-3671	104	38	of	of	ADP
fnp-3671	104	39	alzheimer	alzheimer	PROPN
fnp-3671	104	40	’s	’s	PART
fnp-3671	104	41	disease	disease	NOUN
fnp-3671	104	42	.	.	PUNCT
fnp-3671	105	1	we	we	PRON
fnp-3671	105	2	propose	propose	VERB
fnp-3671	105	3	that	that	SCONJ
fnp-3671	105	4	examining	examine	VERB
fnp-3671	105	5	changes	change	NOUN
fnp-3671	105	6	beyond	beyond	ADP
fnp-3671	105	7	p	p	PROPN
fnp-3671	105	8	-	-	PUNCT
fnp-3671	105	9	tau	tau	PROPN
fnp-3671	105	10	is	be	AUX
fnp-3671	105	11	critical	critical	ADJ
fnp-3671	105	12	to	to	PART
fnp-3671	105	13	understand	understand	VERB
fnp-3671	105	14	mtbi	mtbi	NOUN
fnp-3671	105	15	pathology	pathology	PROPN
fnp-3671	105	16	.	.	PUNCT
fnp-3671	106	1	the	the	DET
fnp-3671	106	2	objective	objective	NOUN
fnp-3671	106	3	of	of	ADP
fnp-3671	106	4	this	this	DET
fnp-3671	106	5	study	study	NOUN
fnp-3671	106	6	is	be	AUX
fnp-3671	106	7	to	to	PART
fnp-3671	106	8	identify	identify	VERB
fnp-3671	106	9	novel	novel	ADJ
fnp-3671	106	10	pathological	pathological	ADJ
fnp-3671	106	11	markers	marker	NOUN
fnp-3671	106	12	of	of	ADP
fnp-3671	106	13	mtbi	mtbi	NOUN
fnp-3671	106	14	which	which	PRON
fnp-3671	106	15	may	may	AUX
fnp-3671	106	16	explain	explain	VERB
fnp-3671	106	17	clinical	clinical	ADJ
fnp-3671	106	18	symptoms	symptom	NOUN
fnp-3671	106	19	and	and	CCONJ
fnp-3671	106	20	allow	allow	VERB
fnp-3671	106	21	for	for	ADP
fnp-3671	106	22	the	the	DET
fnp-3671	106	23	development	development	NOUN
fnp-3671	106	24	of	of	ADP
fnp-3671	106	25	therapeutic	therapeutic	ADJ
fnp-3671	106	26	targets	target	NOUN
fnp-3671	106	27	.	.	PUNCT
fnp-3671	107	1	using	use	VERB
fnp-3671	107	2	a	a	DET
fnp-3671	107	3	brain	brain	NOUN
fnp-3671	107	4	bank	bank	NOUN
fnp-3671	107	5	of	of	ADP
fnp-3671	107	6	former	former	ADJ
fnp-3671	107	7	professional	professional	ADJ
fnp-3671	107	8	athletes	athlete	NOUN
fnp-3671	107	9	with	with	ADP
fnp-3671	107	10	mtbi	mtbi	NOUN
fnp-3671	107	11	history	history	NOUN
fnp-3671	107	12	we	we	PRON
fnp-3671	107	13	used	use	VERB
fnp-3671	107	14	immunohistochemistry	immunohistochemistry	NOUN
fnp-3671	107	15	and	and	CCONJ
fnp-3671	107	16	gene	gene	NOUN
fnp-3671	107	17	expression	expression	NOUN
fnp-3671	107	18	analysis	analysis	NOUN
fnp-3671	107	19	to	to	PART
fnp-3671	107	20	show	show	VERB
fnp-3671	107	21	cellular	cellular	ADJ
fnp-3671	107	22	senescence	senescence	NOUN
fnp-3671	107	23	as	as	ADP
fnp-3671	107	24	a	a	DET
fnp-3671	107	25	mechanism	mechanism	NOUN
fnp-3671	107	26	driving	drive	VERB
fnp-3671	107	27	brain	brain	NOUN
fnp-3671	107	28	dysfunction	dysfunction	NOUN
fnp-3671	107	29	after	after	ADP
fnp-3671	107	30	mtbi	mtbi	PROPN
fnp-3671	107	31	.	.	PUNCT
fnp-3671	108	1	compared	compare	VERB
fnp-3671	108	2	to	to	ADP
fnp-3671	108	3	controls	control	NOUN
fnp-3671	108	4	,	,	PUNCT
fnp-3671	108	5	mtbi	mtbi	NOUN
fnp-3671	108	6	brains	brain	NOUN
fnp-3671	108	7	show	show	VERB
fnp-3671	108	8	widespread	widespread	ADJ
fnp-3671	108	9	dna	dna	NOUN
fnp-3671	108	10	damage	damage	NOUN
fnp-3671	108	11	(	(	PUNCT
fnp-3671	108	12	γh2ax	γh2ax	NUM
fnp-3671	108	13	)	)	PUNCT
fnp-3671	108	14	and	and	CCONJ
fnp-3671	108	15	cellular	cellular	ADJ
fnp-3671	108	16	senescence	senescence	NOUN
fnp-3671	108	17	in	in	ADP
fnp-3671	108	18	ependymal	ependymal	ADJ
fnp-3671	108	19	cells	cell	NOUN
fnp-3671	108	20	,	,	PUNCT
fnp-3671	108	21	astrocytes	astrocyte	NOUN
fnp-3671	108	22	,	,	PUNCT
fnp-3671	108	23	and	and	CCONJ
fnp-3671	108	24	oligodendrocytes	oligodendrocyte	NOUN
fnp-3671	108	25	even	even	ADV
fnp-3671	108	26	in	in	ADP
fnp-3671	108	27	cases	case	NOUN
fnp-3671	108	28	with	with	ADP
fnp-3671	108	29	no	no	DET
fnp-3671	108	30	neuropathology	neuropathology	NOUN
fnp-3671	108	31	.	.	PUNCT
fnp-3671	109	1	gene	gene	NOUN
fnp-3671	109	2	expression	expression	NOUN
fnp-3671	109	3	analysis	analysis	NOUN
fnp-3671	109	4	revealed	reveal	VERB
fnp-3671	109	5	upregulation	upregulation	NOUN
fnp-3671	109	6	of	of	ADP
fnp-3671	109	7	the	the	DET
fnp-3671	109	8	senescence	senescence	NOUN
fnp-3671	109	9	-	-	PUNCT
fnp-3671	109	10	associated	associate	VERB
fnp-3671	109	11	secretory	secretory	ADJ
fnp-3671	109	12	phenotype	phenotype	NOUN
fnp-3671	109	13	(	(	PUNCT
fnp-3671	109	14	sasp	sasp	NOUN
fnp-3671	109	15	)	)	PUNCT
fnp-3671	109	16	,	,	PUNCT
fnp-3671	109	17	a	a	DET
fnp-3671	109	18	form	form	NOUN
fnp-3671	109	19	of	of	ADP
fnp-3671	109	20	chronic	chronic	ADJ
fnp-3671	109	21	low	low	ADJ
fnp-3671	109	22	-	-	PUNCT
fnp-3671	109	23	level	level	NOUN
fnp-3671	109	24	inflammation	inflammation	NOUN
fnp-3671	109	25	which	which	PRON
fnp-3671	109	26	has	have	AUX
fnp-3671	109	27	been	be	AUX
fnp-3671	109	28	proposed	propose	VERB
fnp-3671	109	29	to	to	PART
fnp-3671	109	30	drive	drive	VERB
fnp-3671	109	31	cognitive	cognitive	ADJ
fnp-3671	109	32	dysfunction	dysfunction	NOUN
fnp-3671	109	33	and	and	CCONJ
fnp-3671	109	34	proteinopathy	proteinopathy	ADJ
fnp-3671	109	35	.	.	PUNCT
fnp-3671	110	1	in	in	ADP
fnp-3671	110	2	a	a	DET
fnp-3671	110	3	mouse	mouse	NOUN
fnp-3671	110	4	model	model	NOUN
fnp-3671	110	5	of	of	ADP
fnp-3671	110	6	mtbi	mtbi	PROPN
fnp-3671	110	7	,	,	PUNCT
fnp-3671	110	8	we	we	PRON
fnp-3671	110	9	have	have	AUX
fnp-3671	110	10	recapitulated	recapitulate	VERB
fnp-3671	110	11	these	these	DET
fnp-3671	110	12	results	result	NOUN
fnp-3671	110	13	and	and	CCONJ
fnp-3671	110	14	shown	show	VERB
fnp-3671	110	15	that	that	SCONJ
fnp-3671	110	16	eliminating	eliminate	VERB
fnp-3671	110	17	senescent	senescent	ADJ
fnp-3671	110	18	cells	cell	NOUN
fnp-3671	110	19	with	with	ADP
fnp-3671	110	20	senolytic	senolytic	ADJ
fnp-3671	110	21	therapy	therapy	NOUN
fnp-3671	110	22	is	be	AUX
fnp-3671	110	23	beneficial	beneficial	ADJ
fnp-3671	110	24	.	.	PUNCT
fnp-3671	111	1	mtbi	mtbi	NOUN
fnp-3671	111	2	brains	brain	NOUN
fnp-3671	111	3	are	be	AUX
fnp-3671	111	4	characterized	characterize	VERB
fnp-3671	111	5	by	by	ADP
fnp-3671	111	6	early	early	ADJ
fnp-3671	111	7	ageing	age	VERB
fnp-3671	111	8	through	through	ADP
fnp-3671	111	9	cellular	cellular	ADJ
fnp-3671	111	10	senescence	senescence	NOUN
fnp-3671	111	11	,	,	PUNCT
fnp-3671	111	12	which	which	PRON
fnp-3671	111	13	may	may	AUX
fnp-3671	111	14	drive	drive	VERB
fnp-3671	111	15	clinical	clinical	ADJ
fnp-3671	111	16	symptoms	symptom	NOUN
fnp-3671	111	17	and	and	CCONJ
fnp-3671	111	18	p	p	NOUN
fnp-3671	111	19	-	-	PUNCT
fnp-3671	111	20	tau	tau	PROPN
fnp-3671	111	21	pathology	pathology	NOUN
fnp-3671	111	22	.	.	PUNCT
fnp-3671	111	23	  	  	SPACE
fnp-3671	112	1	abstract	abstract	ADJ
fnp-3671	112	2	10	10	NUM
fnp-3671	112	3	free	free	ADJ
fnp-3671	112	4	neuropathol	neuropathol	NOUN
fnp-3671	112	5	2:29:13	2:29:13	NUM
fnp-3671	112	6	hail	hail	NOUN
fnp-3671	112	7	to	to	PART
fnp-3671	112	8	astrogliosis	astrogliosis	VERB
fnp-3671	112	9	!	!	PUNCT
fnp-3671	113	1	the	the	DET
fnp-3671	113	2	unsung	unsung	ADJ
fnp-3671	113	3	hero	hero	NOUN
fnp-3671	113	4	of	of	ADP
fnp-3671	113	5	the	the	DET
fnp-3671	113	6	cns	cns	NOUN
fnp-3671	113	7	tissue	tissue	NOUN
fnp-3671	113	8	reaction	reaction	NOUN
fnp-3671	113	9	to	to	ADP
fnp-3671	113	10	the	the	DET
fnp-3671	113	11	spinal	spinal	PROPN
fnp-3671	113	12	cord	cord	NOUN
fnp-3671	113	13	injury	injury	NOUN
fnp-3671	113	14	.	.	PUNCT
fnp-3671	114	1	jacek	jacek	PROPN
fnp-3671	114	2	m.	m.	PROPN
fnp-3671	114	3	kwiecien1	kwiecien1	PROPN
fnp-3671	114	4	1	1	NUM
fnp-3671	114	5	department	department	NOUN
fnp-3671	114	6	of	of	ADP
fnp-3671	114	7	pathology	pathology	NOUN
fnp-3671	114	8	and	and	CCONJ
fnp-3671	114	9	molecular	molecular	ADJ
fnp-3671	114	10	medicine	medicine	NOUN
fnp-3671	114	11	,	,	PUNCT
fnp-3671	114	12	faculty	faculty	NOUN
fnp-3671	114	13	of	of	ADP
fnp-3671	114	14	health	health	NOUN
fnp-3671	114	15	sciences	sciences	PROPN
fnp-3671	114	16	,	,	PUNCT
fnp-3671	114	17	mcmaster	mcmaster	PROPN
fnp-3671	114	18	university	university	PROPN
fnp-3671	114	19	,	,	PUNCT
fnp-3671	114	20	hamilton	hamilton	PROPN
fnp-3671	114	21	,	,	PUNCT
fnp-3671	114	22	ontario	ontario	PROPN
fnp-3671	114	23	,	,	PUNCT
fnp-3671	114	24	canada	canada	PROPN
fnp-3671	114	25	spinal	spinal	PROPN
fnp-3671	114	26	trauma	trauma	NOUN
fnp-3671	114	27	results	result	NOUN
fnp-3671	114	28	in	in	ADP
fnp-3671	114	29	a	a	DET
fnp-3671	114	30	localized	localize	VERB
fnp-3671	114	31	spinal	spinal	NOUN
fnp-3671	114	32	cord	cord	NOUN
fnp-3671	114	33	injury	injury	NOUN
fnp-3671	114	34	(	(	PUNCT
fnp-3671	114	35	sci	sci	PROPN
fnp-3671	114	36	)	)	PUNCT
fnp-3671	114	37	with	with	ADP
fnp-3671	114	38	an	an	DET
fnp-3671	114	39	area	area	NOUN
fnp-3671	114	40	of	of	ADP
fnp-3671	114	41	hemorrhage	hemorrhage	NOUN
fnp-3671	114	42	and	and	CCONJ
fnp-3671	114	43	necrosis	necrosis	NOUN
fnp-3671	114	44	surrounded	surround	VERB
fnp-3671	114	45	by	by	ADP
fnp-3671	114	46	edema	edema	NOUN
fnp-3671	114	47	in	in	ADP
fnp-3671	114	48	acute	acute	ADJ
fnp-3671	114	49	phase	phase	NOUN
fnp-3671	114	50	that	that	PRON
fnp-3671	114	51	lasts	last	VERB
fnp-3671	114	52	2	2	NUM
fnp-3671	114	53	days	day	NOUN
fnp-3671	114	54	followed	follow	VERB
fnp-3671	114	55	by	by	ADP
fnp-3671	114	56	an	an	DET
fnp-3671	114	57	inflammatory	inflammatory	ADJ
fnp-3671	114	58	phase	phase	NOUN
fnp-3671	114	59	beginning	begin	VERB
fnp-3671	114	60	on	on	ADP
fnp-3671	114	61	day	day	NOUN
fnp-3671	114	62	3	3	NUM
fnp-3671	114	63	with	with	ADP
fnp-3671	114	64	infiltration	infiltration	NOUN
fnp-3671	114	65	of	of	ADP
fnp-3671	114	66	necrosis	necrosis	NOUN
fnp-3671	114	67	by	by	ADP
fnp-3671	114	68	inflammatory	inflammatory	ADJ
fnp-3671	114	69	cd68+/cd163macrophages	cd68+/cd163macrophage	NOUN
fnp-3671	114	70	whose	whose	DET
fnp-3671	114	71	numbers	number	NOUN
fnp-3671	114	72	rapidly	rapidly	ADV
fnp-3671	114	73	increase	increase	VERB
fnp-3671	114	74	and	and	CCONJ
fnp-3671	114	75	persist	persist	VERB
fnp-3671	114	76	at	at	ADP
fnp-3671	114	77	high	high	ADJ
fnp-3671	114	78	levels	level	NOUN
fnp-3671	114	79	for	for	ADP
fnp-3671	114	80	4	4	NUM
fnp-3671	114	81	weeks	week	NOUN
fnp-3671	114	82	and	and	CCONJ
fnp-3671	114	83	then	then	ADV
fnp-3671	114	84	decline	decline	VERB
fnp-3671	114	85	but	but	CCONJ
fnp-3671	114	86	are	be	AUX
fnp-3671	114	87	still	still	ADV
fnp-3671	114	88	present	present	ADJ
fnp-3671	114	89	in	in	ADP
fnp-3671	114	90	low	low	ADJ
fnp-3671	114	91	numbers	number	NOUN
fnp-3671	114	92	at	at	ADP
fnp-3671	114	93	16	16	NUM
fnp-3671	114	94	weeks	week	NOUN
fnp-3671	114	95	.	.	PUNCT
fnp-3671	115	1	this	this	DET
fnp-3671	115	2	destructive	destructive	ADJ
fnp-3671	115	3	inflammation	inflammation	NOUN
fnp-3671	115	4	is	be	AUX
fnp-3671	115	5	fuelled	fuel	VERB
fnp-3671	115	6	by	by	ADP
fnp-3671	115	7	myelin	myelin	NOUN
fnp-3671	115	8	-	-	PUNCT
fnp-3671	115	9	rich	rich	ADJ
fnp-3671	115	10	necrotic	necrotic	ADJ
fnp-3671	115	11	debris	debris	NOUN
fnp-3671	115	12	and	and	CCONJ
fnp-3671	115	13	the	the	DET
fnp-3671	115	14	macrophage	macrophage	ADJ
fnp-3671	115	15	activation	activation	NOUN
fnp-3671	115	16	causes	cause	VERB
fnp-3671	115	17	ongoing	ongoing	ADJ
fnp-3671	115	18	damage	damage	NOUN
fnp-3671	115	19	to	to	ADP
fnp-3671	115	20	the	the	DET
fnp-3671	115	21	surrounding	surround	VERB
fnp-3671	115	22	spinal	spinal	ADJ
fnp-3671	115	23	cord	cord	NOUN
fnp-3671	115	24	and	and	CCONJ
fnp-3671	115	25	further	far	ADV
fnp-3671	115	26	damaged	damage	VERB
fnp-3671	115	27	myelin	myelin	NOUN
fnp-3671	115	28	to	to	PART
fnp-3671	115	29	sustain	sustain	VERB
fnp-3671	115	30	a	a	DET
fnp-3671	115	31	mechanism	mechanism	NOUN
fnp-3671	115	32	of	of	ADP
fnp-3671	115	33	vicious	vicious	ADJ
fnp-3671	115	34	cycle	cycle	NOUN
fnp-3671	115	35	.	.	PUNCT
fnp-3671	116	1	the	the	DET
fnp-3671	116	2	severity	severity	NOUN
fnp-3671	116	3	of	of	ADP
fnp-3671	116	4	post	post	ADJ
fnp-3671	116	5	-	-	ADJ
fnp-3671	116	6	sci	sci	ADJ
fnp-3671	116	7	inflammation	inflammation	NOUN
fnp-3671	116	8	becomes	become	VERB
fnp-3671	116	9	inhibited	inhibited	ADJ
fnp-3671	116	10	and	and	CCONJ
fnp-3671	116	11	eliminated	eliminate	VERB
fnp-3671	116	12	by	by	ADP
fnp-3671	116	13	a	a	DET
fnp-3671	116	14	spinal	spinal	ADJ
fnp-3671	116	15	cord	cord	NOUN
fnp-3671	116	16	tissue	tissue	NOUN
fnp-3671	116	17	response	response	NOUN
fnp-3671	116	18	in	in	ADP
fnp-3671	116	19	the	the	DET
fnp-3671	116	20	3rd	3rd	ADJ
fnp-3671	116	21	phase	phase	NOUN
fnp-3671	116	22	,	,	PUNCT
fnp-3671	116	23	resolution	resolution	NOUN
fnp-3671	116	24	.	.	PUNCT
fnp-3671	117	1	astrogliosis	astrogliosis	NOUN
fnp-3671	117	2	is	be	AUX
fnp-3671	117	3	a	a	DET
fnp-3671	117	4	hallmark	hallmark	NOUN
fnp-3671	117	5	of	of	ADP
fnp-3671	117	6	reaction	reaction	NOUN
fnp-3671	117	7	to	to	ADP
fnp-3671	117	8	sci	sci	PROPN
fnp-3671	117	9	.	.	PUNCT
fnp-3671	118	1	in	in	ADP
fnp-3671	118	2	the	the	DET
fnp-3671	118	3	1st	1st	ADJ
fnp-3671	118	4	week	week	NOUN
fnp-3671	118	5	astrocytes	astrocyte	NOUN
fnp-3671	118	6	surrounding	surround	VERB
fnp-3671	118	7	the	the	DET
fnp-3671	118	8	lesion	lesion	NOUN
fnp-3671	118	9	hypertrophy	hypertrophy	NOUN
fnp-3671	118	10	and	and	CCONJ
fnp-3671	118	11	define	define	VERB
fnp-3671	118	12	a	a	DET
fnp-3671	118	13	cavity	cavity	NOUN
fnp-3671	118	14	of	of	ADP
fnp-3671	118	15	injury	injury	NOUN
fnp-3671	118	16	(	(	PUNCT
fnp-3671	118	17	coi	coi	NOUN
fnp-3671	118	18	)	)	PUNCT
fnp-3671	118	19	containing	contain	VERB
fnp-3671	118	20	macrophage	macrophage	ADJ
fnp-3671	118	21	-	-	PUNCT
fnp-3671	118	22	rich	rich	ADJ
fnp-3671	118	23	inflammation	inflammation	NOUN
fnp-3671	118	24	and	and	CCONJ
fnp-3671	118	25	accumulation	accumulation	NOUN
fnp-3671	118	26	of	of	ADP
fnp-3671	118	27	water	water	NOUN
fnp-3671	118	28	.	.	PUNCT
fnp-3671	119	1	progression	progression	NOUN
fnp-3671	119	2	of	of	ADP
fnp-3671	119	3	severity	severity	NOUN
fnp-3671	119	4	of	of	ADP
fnp-3671	119	5	astrogliosis	astrogliosis	NOUN
fnp-3671	119	6	around	around	ADP
fnp-3671	119	7	the	the	DET
fnp-3671	119	8	coi	coi	NOUN
fnp-3671	119	9	coincides	coincide	VERB
fnp-3671	119	10	with	with	ADP
fnp-3671	119	11	the	the	DET
fnp-3671	119	12	reduction	reduction	NOUN
fnp-3671	119	13	of	of	ADP
fnp-3671	119	14	numbers	number	NOUN
fnp-3671	119	15	of	of	ADP
fnp-3671	119	16	macrophages	macrophage	NOUN
fnp-3671	119	17	and	and	CCONJ
fnp-3671	119	18	leads	lead	VERB
fnp-3671	119	19	to	to	ADP
fnp-3671	119	20	formation	formation	NOUN
fnp-3671	119	21	of	of	ADP
fnp-3671	119	22	quiescent	quiescent	ADJ
fnp-3671	119	23	syrinx	syrinx	NOUN
fnp-3671	119	24	.	.	PUNCT
fnp-3671	120	1	while	while	SCONJ
fnp-3671	120	2	the	the	DET
fnp-3671	120	3	inflammation	inflammation	NOUN
fnp-3671	120	4	in	in	ADP
fnp-3671	120	5	the	the	DET
fnp-3671	120	6	coi	coi	NOUN
fnp-3671	120	7	leads	lead	VERB
fnp-3671	120	8	to	to	ADP
fnp-3671	120	9	damage	damage	NOUN
fnp-3671	120	10	of	of	ADP
fnp-3671	120	11	blood	blood	NOUN
fnp-3671	120	12	vessel	vessel	NOUN
fnp-3671	120	13	in	in	ADP
fnp-3671	120	14	the	the	DET
fnp-3671	120	15	surrounding	surround	VERB
fnp-3671	120	16	spinal	spinal	ADJ
fnp-3671	120	17	cord	cord	NOUN
fnp-3671	120	18	resulting	result	VERB
fnp-3671	120	19	in	in	ADP
fnp-3671	120	20	vasogenic	vasogenic	ADJ
fnp-3671	120	21	edema	edema	NOUN
fnp-3671	120	22	beyond	beyond	ADP
fnp-3671	120	23	16	16	NUM
fnp-3671	120	24	weeks	week	NOUN
fnp-3671	120	25	post	post	PROPN
fnp-3671	120	26	-	-	ADJ
fnp-3671	120	27	sci	sci	ADJ
fnp-3671	120	28	,	,	PUNCT
fnp-3671	120	29	astrocytes	astrocyte	NOUN
fnp-3671	120	30	equipped	equip	VERB
fnp-3671	120	31	with	with	ADP
fnp-3671	120	32	aquaporin-4	aquaporin-4	PRON
fnp-3671	120	33	pass	pass	VERB
fnp-3671	120	34	excess	excess	ADJ
fnp-3671	120	35	edema	edema	NOUN
fnp-3671	120	36	water	water	NOUN
fnp-3671	120	37	to	to	ADP
fnp-3671	120	38	4	4	NUM
fnp-3671	120	39	extra	extra	ADJ
fnp-3671	120	40	-	-	ADJ
fnp-3671	120	41	spinal	spinal	ADJ
fnp-3671	120	42	spaces	space	NOUN
fnp-3671	120	43	;	;	PUNCT
fnp-3671	120	44	(	(	PUNCT
fnp-3671	120	45	1	1	X
fnp-3671	120	46	)	)	PUNCT
fnp-3671	120	47	the	the	DET
fnp-3671	120	48	sub	sub	NOUN
fnp-3671	120	49	-	-	ADJ
fnp-3671	120	50	arachnoid	arachnoid	ADJ
fnp-3671	120	51	,	,	PUNCT
fnp-3671	120	52	(	(	PUNCT
fnp-3671	120	53	2	2	X
fnp-3671	120	54	)	)	PUNCT
fnp-3671	120	55	the	the	DET
fnp-3671	120	56	central	central	ADJ
fnp-3671	120	57	canal	canal	NOUN
fnp-3671	120	58	,	,	PUNCT
fnp-3671	120	59	(	(	PUNCT
fnp-3671	120	60	3	3	X
fnp-3671	120	61	)	)	PUNCT
fnp-3671	120	62	the	the	DET
fnp-3671	120	63	blood	blood	NOUN
fnp-3671	120	64	vessels	vessel	NOUN
fnp-3671	120	65	,	,	PUNCT
fnp-3671	120	66	and	and	CCONJ
fnp-3671	120	67	(	(	PUNCT
fnp-3671	120	68	4	4	X
fnp-3671	120	69	)	)	PUNCT
fnp-3671	120	70	the	the	DET
fnp-3671	120	71	coi	coi	NOUN
fnp-3671	120	72	,	,	PUNCT
fnp-3671	120	73	a	a	DET
fnp-3671	120	74	novel	novel	ADJ
fnp-3671	120	75	mechanism	mechanism	NOUN
fnp-3671	120	76	.	.	PUNCT
fnp-3671	121	1	astrogliosis	astrogliosis	NOUN
fnp-3671	121	2	is	be	AUX
fnp-3671	121	3	a	a	DET
fnp-3671	121	4	beneficial	beneficial	ADJ
fnp-3671	121	5	element	element	NOUN
fnp-3671	121	6	in	in	ADP
fnp-3671	121	7	neuroplasticity	neuroplasticity	NOUN
fnp-3671	121	8	following	follow	VERB
fnp-3671	121	9	the	the	DET
fnp-3671	121	10	sci	sci	PROPN
fnp-3671	121	11	and	and	CCONJ
fnp-3671	121	12	should	should	AUX
fnp-3671	121	13	not	not	PART
fnp-3671	121	14	be	be	AUX
fnp-3671	121	15	inhibited	inhibit	VERB
fnp-3671	121	16	in	in	ADP
fnp-3671	121	17	anti	anti	ADJ
fnp-3671	121	18	-	-	ADJ
fnp-3671	121	19	inflammatory	inflammatory	ADJ
fnp-3671	121	20	treatments	treatment	NOUN
fnp-3671	121	21	effecting	effect	VERB
fnp-3671	121	22	neuroprotection	neuroprotection	NOUN
fnp-3671	121	23	.	.	PUNCT
fnp-3671	121	24	  	  	SPACE
fnp-3671	122	1	abstract	abstract	ADJ
fnp-3671	122	2	11	11	NUM
fnp-3671	122	3	free	free	ADJ
fnp-3671	122	4	neuropathol	neuropathol	NOUN
fnp-3671	122	5	2:29:14	2:29:14	NUM
fnp-3671	122	6	ischemic	ischemic	ADJ
fnp-3671	122	7	-	-	PUNCT
fnp-3671	122	8	like	like	ADJ
fnp-3671	122	9	pathology	pathology	NOUN
fnp-3671	122	10	in	in	ADP
fnp-3671	122	11	aberrant	aberrant	ADJ
fnp-3671	122	12	white	white	ADJ
fnp-3671	122	13	matter	matter	NOUN
fnp-3671	122	14	tracts	tract	NOUN
fnp-3671	122	15	of	of	ADP
fnp-3671	122	16	fetal	fetal	ADJ
fnp-3671	122	17	holoprosencephaly	holoprosencephaly	NOUN
fnp-3671	122	18	:	:	PUNCT
fnp-3671	122	19	a	a	DET
fnp-3671	122	20	case	case	NOUN
fnp-3671	122	21	series	series	NOUN
fnp-3671	122	22	sumit	sumit	PROPN
fnp-3671	122	23	das1	das1	PROPN
fnp-3671	122	24	,	,	PUNCT
fnp-3671	122	25	jessica	jessica	PROPN
fnp-3671	122	26	saunders2	saunders2	PROPN
fnp-3671	122	27	,	,	PUNCT
fnp-3671	122	28	sarah	sarah	PROPN
fnp-3671	122	29	nikkel3	nikkel3	VERB
fnp-3671	122	30	,	,	PUNCT
fnp-3671	122	31	lindsay	lindsay	PROPN
fnp-3671	122	32	brown4	brown4	PROPN
fnp-3671	122	33	,	,	PUNCT
fnp-3671	122	34	christopher	christopher	PROPN
fnp-3671	122	35	dunham2	dunham2	PROPN
fnp-3671	122	36	1	1	NUM
fnp-3671	122	37	department	department	NOUN
fnp-3671	122	38	of	of	ADP
fnp-3671	122	39	pathology	pathology	NOUN
fnp-3671	122	40	and	and	CCONJ
fnp-3671	122	41	lab	lab	NOUN
fnp-3671	122	42	medicine	medicine	NOUN
fnp-3671	122	43	,	,	PUNCT
fnp-3671	122	44	university	university	NOUN
fnp-3671	122	45	hospital	hospital	NOUN
fnp-3671	122	46	,	,	PUNCT
fnp-3671	122	47	edmonton	edmonton	PROPN
fnp-3671	122	48	,	,	PUNCT
fnp-3671	122	49	alberta	alberta	PROPN
fnp-3671	122	50	,	,	PUNCT
fnp-3671	122	51	canada	canada	PROPN
fnp-3671	122	52	2	2	NUM
fnp-3671	122	53	division	division	NOUN
fnp-3671	122	54	of	of	ADP
fnp-3671	122	55	anatomical	anatomical	ADJ
fnp-3671	122	56	pathology	pathology	NOUN
fnp-3671	122	57	,	,	PUNCT
fnp-3671	122	58	bc	bc	PROPN
fnp-3671	122	59	children	children	PROPN
fnp-3671	122	60	’s	’s	PART
fnp-3671	122	61	hospital	hospital	NOUN
fnp-3671	122	62	,	,	PUNCT
fnp-3671	122	63	vancouver	vancouver	PROPN
fnp-3671	122	64	,	,	PUNCT
fnp-3671	122	65	british	british	PROPN
fnp-3671	122	66	columbia	columbia	PROPN
fnp-3671	122	67	,	,	PUNCT
fnp-3671	122	68	canada	canada	PROPN
fnp-3671	122	69	3	3	NUM
fnp-3671	122	70	department	department	PROPN
fnp-3671	122	71	of	of	ADP
fnp-3671	122	72	medical	medical	ADJ
fnp-3671	122	73	genetics	genetic	NOUN
fnp-3671	122	74	,	,	PUNCT
fnp-3671	122	75	bc	bc	PROPN
fnp-3671	122	76	children	children	PROPN
fnp-3671	122	77	’s	’s	PART
fnp-3671	122	78	hospital	hospital	NOUN
fnp-3671	122	79	,	,	PUNCT
fnp-3671	122	80	vancouver	vancouver	PROPN
fnp-3671	122	81	,	,	PUNCT
fnp-3671	122	82	british	british	PROPN
fnp-3671	122	83	columbia	columbia	PROPN
fnp-3671	122	84	,	,	PUNCT
fnp-3671	122	85	canada	canada	PROPN
fnp-3671	122	86	4	4	NUM
fnp-3671	122	87	division	division	NOUN
fnp-3671	122	88	of	of	ADP
fnp-3671	122	89	genome	genome	NOUN
fnp-3671	122	90	diagnostics	diagnostic	NOUN
fnp-3671	122	91	,	,	PUNCT
fnp-3671	122	92	bc	bc	PROPN
fnp-3671	122	93	children	children	PROPN
fnp-3671	122	94	’s	’s	PART
fnp-3671	122	95	hospital	hospital	NOUN
fnp-3671	122	96	,	,	PUNCT
fnp-3671	122	97	vancouver	vancouver	PROPN
fnp-3671	122	98	,	,	PUNCT
fnp-3671	122	99	british	british	PROPN
fnp-3671	122	100	columbia	columbia	PROPN
fnp-3671	122	101	,	,	PUNCT
fnp-3671	122	102	canada	canada	PROPN
fnp-3671	122	103	holoprosencephaly	holoprosencephaly	PROPN
fnp-3671	122	104	(	(	PUNCT
fnp-3671	122	105	hpe	hpe	PROPN
fnp-3671	122	106	)	)	PUNCT
fnp-3671	122	107	is	be	AUX
fnp-3671	122	108	due	due	ADJ
fnp-3671	122	109	to	to	ADP
fnp-3671	122	110	defective	defective	ADJ
fnp-3671	122	111	early	early	ADJ
fnp-3671	122	112	forebrain	forebrain	NOUN
fnp-3671	122	113	induction	induction	NOUN
fnp-3671	122	114	resulting	result	VERB
fnp-3671	122	115	in	in	ADP
fnp-3671	122	116	a	a	DET
fnp-3671	122	117	“	"	PUNCT
fnp-3671	122	118	lack	lack	NOUN
fnp-3671	122	119	of	of	ADP
fnp-3671	122	120	cleavage	cleavage	NOUN
fnp-3671	122	121	”	"	PUNCT
fnp-3671	122	122	of	of	ADP
fnp-3671	122	123	the	the	DET
fnp-3671	122	124	primitive	primitive	ADJ
fnp-3671	122	125	prosencephalon	prosencephalon	NOUN
fnp-3671	122	126	into	into	ADP
fnp-3671	122	127	paired	pair	VERB
fnp-3671	122	128	cerebral	cerebral	ADJ
fnp-3671	122	129	hemispheres	hemisphere	NOUN
fnp-3671	122	130	.	.	PUNCT
fnp-3671	123	1	hpe	hpe	PROPN
fnp-3671	123	2	is	be	AUX
fnp-3671	123	3	generally	generally	ADV
fnp-3671	123	4	considered	consider	VERB
fnp-3671	123	5	sporadic	sporadic	ADJ
fnp-3671	123	6	,	,	PUNCT
fnp-3671	123	7	although	although	SCONJ
fnp-3671	123	8	clear	clear	ADJ
fnp-3671	123	9	environmental	environmental	ADJ
fnp-3671	123	10	and	and	CCONJ
fnp-3671	123	11	genetic	genetic	ADJ
fnp-3671	123	12	factors	factor	NOUN
fnp-3671	123	13	have	have	AUX
fnp-3671	123	14	been	be	AUX
fnp-3671	123	15	recognized	recognize	VERB
fnp-3671	123	16	.	.	PUNCT
fnp-3671	124	1	from	from	ADP
fnp-3671	124	2	a	a	DET
fnp-3671	124	3	genetic	genetic	ADJ
fnp-3671	124	4	perspective	perspective	NOUN
fnp-3671	124	5	,	,	PUNCT
fnp-3671	124	6	an	an	DET
fnp-3671	124	7	autosomal	autosomal	ADJ
fnp-3671	124	8	dominant	dominant	ADJ
fnp-3671	124	9	inheritance	inheritance	NOUN
fnp-3671	124	10	pattern	pattern	NOUN
fnp-3671	124	11	is	be	AUX
fnp-3671	124	12	most	most	ADV
fnp-3671	124	13	commonly	commonly	ADV
fnp-3671	124	14	noted	note	VERB
fnp-3671	124	15	.	.	PUNCT
fnp-3671	125	1	chromosomal	chromosomal	ADJ
fnp-3671	125	2	abnormalities	abnormality	NOUN
fnp-3671	125	3	are	be	AUX
fnp-3671	125	4	common	common	ADJ
fnp-3671	125	5	in	in	ADP
fnp-3671	125	6	hpe	hpe	PROPN
fnp-3671	125	7	,	,	PUNCT
fnp-3671	125	8	seen	see	VERB
fnp-3671	125	9	in	in	ADP
fnp-3671	125	10	25	25	NUM
fnp-3671	125	11	-	-	SYM
fnp-3671	125	12	50	50	NUM
fnp-3671	125	13	%	%	NOUN
fnp-3671	125	14	of	of	ADP
fnp-3671	125	15	affected	affected	ADJ
fnp-3671	125	16	individuals	individual	NOUN
fnp-3671	125	17	,	,	PUNCT
fnp-3671	125	18	with	with	ADP
fnp-3671	125	19	trisomy	trisomy	NOUN
fnp-3671	125	20	13	13	NUM
fnp-3671	125	21	being	be	AUX
fnp-3671	125	22	the	the	DET
fnp-3671	125	23	most	most	ADV
fnp-3671	125	24	frequent	frequent	ADJ
fnp-3671	125	25	.	.	PUNCT
fnp-3671	126	1	a	a	DET
fnp-3671	126	2	number	number	NOUN
fnp-3671	126	3	of	of	ADP
fnp-3671	126	4	structural	structural	ADJ
fnp-3671	126	5	chromosomal	chromosomal	ADJ
fnp-3671	126	6	abnormalities	abnormality	NOUN
fnp-3671	126	7	(	(	PUNCT
fnp-3671	126	8	e.g.	e.g.	ADV
fnp-3671	126	9	,	,	PUNCT
fnp-3671	126	10	21q22.3	21q22.3	NUM
fnp-3671	126	11	deletion	deletion	NOUN
fnp-3671	126	12	)	)	PUNCT
fnp-3671	126	13	and	and	CCONJ
fnp-3671	126	14	pathogenic	pathogenic	ADJ
fnp-3671	126	15	copy	copy	NOUN
fnp-3671	126	16	number	number	NOUN
fnp-3671	126	17	variations	variation	NOUN
fnp-3671	126	18	have	have	AUX
fnp-3671	126	19	also	also	ADV
fnp-3671	126	20	been	be	AUX
fnp-3671	126	21	described	describe	VERB
fnp-3671	126	22	,	,	PUNCT
fnp-3671	126	23	as	as	SCONJ
fnp-3671	126	24	have	have	VERB
fnp-3671	126	25	syndromic	syndromic	ADJ
fnp-3671	126	26	associations	association	NOUN
fnp-3671	126	27	.	.	PUNCT
fnp-3671	127	1	pertinent	pertinent	ADJ
fnp-3671	127	2	biologic	biologic	NOUN
fnp-3671	127	3	pathways	pathway	NOUN
fnp-3671	127	4	include	include	VERB
fnp-3671	127	5	shh	shh	PROPN
fnp-3671	127	6	,	,	PUNCT
fnp-3671	127	7	nodal	nodal	NOUN
fnp-3671	127	8	and	and	CCONJ
fnp-3671	127	9	bmp	bmp	NOUN
fnp-3671	127	10	;	;	PUNCT
fnp-3671	127	11	in	in	ADP
fnp-3671	127	12	turn	turn	NOUN
fnp-3671	127	13	,	,	PUNCT
fnp-3671	127	14	several	several	ADJ
fnp-3671	127	15	single	single	ADJ
fnp-3671	127	16	gene	gene	NOUN
fnp-3671	127	17	mutations	mutation	NOUN
fnp-3671	127	18	related	relate	VERB
fnp-3671	127	19	to	to	ADP
fnp-3671	127	20	these	these	DET
fnp-3671	127	21	pathways	pathway	NOUN
fnp-3671	127	22	have	have	AUX
fnp-3671	127	23	been	be	AUX
fnp-3671	127	24	uncovered	uncover	VERB
fnp-3671	127	25	,	,	PUNCT
fnp-3671	127	26	including	include	VERB
fnp-3671	127	27	shh	shh	PROPN
fnp-3671	127	28	,	,	PUNCT
fnp-3671	127	29	zic2	zic2	PROPN
fnp-3671	127	30	,	,	PUNCT
fnp-3671	127	31	and	and	CCONJ
fnp-3671	127	32	six3	six3	PROPN
fnp-3671	127	33	.	.	PUNCT
fnp-3671	128	1	although	although	SCONJ
fnp-3671	128	2	not	not	PART
fnp-3671	128	3	frequently	frequently	ADV
fnp-3671	128	4	emphasized	emphasize	VERB
fnp-3671	128	5	in	in	ADP
fnp-3671	128	6	neuropathologic	neuropathologic	ADJ
fnp-3671	128	7	descriptions	description	NOUN
fnp-3671	128	8	of	of	ADP
fnp-3671	128	9	hpe	hpe	PROPN
fnp-3671	128	10	,	,	PUNCT
fnp-3671	128	11	abnormal	abnormal	ADJ
fnp-3671	128	12	white	white	ADJ
fnp-3671	128	13	matter	matter	NOUN
fnp-3671	128	14	has	have	AUX
fnp-3671	128	15	been	be	AUX
fnp-3671	128	16	reported	report	VERB
fnp-3671	128	17	,	,	PUNCT
fnp-3671	128	18	mainly	mainly	ADV
fnp-3671	128	19	in	in	ADP
fnp-3671	128	20	the	the	DET
fnp-3671	128	21	form	form	NOUN
fnp-3671	128	22	of	of	ADP
fnp-3671	128	23	aberrant	aberrant	ADJ
fnp-3671	128	24	tracts	tract	NOUN
fnp-3671	128	25	(	(	PUNCT
fnp-3671	128	26	e.g.	e.g.	ADV
fnp-3671	128	27	,	,	PUNCT
fnp-3671	128	28	absence	absence	NOUN
fnp-3671	128	29	of	of	ADP
fnp-3671	128	30	the	the	DET
fnp-3671	128	31	corpus	corpus	NOUN
fnp-3671	128	32	callosum	callosum	NOUN
fnp-3671	128	33	and	and	CCONJ
fnp-3671	128	34	hypoplasia	hypoplasia	NOUN
fnp-3671	128	35	of	of	ADP
fnp-3671	128	36	the	the	DET
fnp-3671	128	37	corticospinal	corticospinal	ADJ
fnp-3671	128	38	pathway	pathway	NOUN
fnp-3671	128	39	)	)	PUNCT
fnp-3671	128	40	.	.	PUNCT
fnp-3671	129	1	in	in	ADP
fnp-3671	129	2	this	this	DET
fnp-3671	129	3	study	study	NOUN
fnp-3671	129	4	,	,	PUNCT
fnp-3671	129	5	we	we	PRON
fnp-3671	129	6	detail	detail	VERB
fnp-3671	129	7	the	the	DET
fnp-3671	129	8	clinicopathologic	clinicopathologic	ADJ
fnp-3671	129	9	features	feature	NOUN
fnp-3671	129	10	of	of	ADP
fnp-3671	129	11	8	8	NUM
fnp-3671	129	12	fetal	fetal	ADJ
fnp-3671	129	13	bcch	bcch	NOUN
fnp-3671	129	14	cases	case	NOUN
fnp-3671	129	15	bearing	bear	VERB
fnp-3671	129	16	a	a	DET
fnp-3671	129	17	seemingly	seemingly	ADV
fnp-3671	129	18	unique	unique	ADJ
fnp-3671	129	19	dual	dual	ADJ
fnp-3671	129	20	form	form	NOUN
fnp-3671	129	21	of	of	ADP
fnp-3671	129	22	white	white	ADJ
fnp-3671	129	23	pathology	pathology	NOUN
fnp-3671	129	24	.	.	PUNCT
fnp-3671	130	1	all	all	DET
fnp-3671	130	2	8	8	NUM
fnp-3671	130	3	cases	case	NOUN
fnp-3671	130	4	demonstrated	demonstrate	VERB
fnp-3671	130	5	ischemic	ischemic	ADJ
fnp-3671	130	6	-	-	PUNCT
fnp-3671	130	7	like	like	ADJ
fnp-3671	130	8	pathology	pathology	NOUN
fnp-3671	130	9	,	,	PUNCT
fnp-3671	130	10	with	with	ADP
fnp-3671	130	11	7	7	NUM
fnp-3671	130	12	of	of	ADP
fnp-3671	130	13	8	8	NUM
fnp-3671	130	14	exhibiting	exhibit	VERB
fnp-3671	130	15	such	such	ADJ
fnp-3671	130	16	pathology	pathology	NOUN
fnp-3671	130	17	in	in	ADP
fnp-3671	130	18	a	a	DET
fnp-3671	130	19	similar	similar	ADJ
fnp-3671	130	20	location	location	NOUN
fnp-3671	130	21	–	–	PUNCT
fnp-3671	130	22	ventral	ventral	ADJ
fnp-3671	130	23	to	to	ADP
fnp-3671	130	24	the	the	DET
fnp-3671	130	25	fused	fuse	VERB
fnp-3671	130	26	deep	deep	ADJ
fnp-3671	130	27	grey	grey	NOUN
fnp-3671	130	28	nuclei	nucleus	NOUN
fnp-3671	130	29	.	.	PUNCT
fnp-3671	131	1	diffusion	diffusion	NOUN
fnp-3671	131	2	tensor	tensor	NOUN
fnp-3671	131	3	imaging	imaging	NOUN
fnp-3671	131	4	(	(	PUNCT
fnp-3671	131	5	dti	dti	PROPN
fnp-3671	131	6	)	)	PUNCT
fnp-3671	131	7	studies	study	NOUN
fnp-3671	131	8	suggest	suggest	VERB
fnp-3671	131	9	that	that	SCONJ
fnp-3671	131	10	the	the	DET
fnp-3671	131	11	neuroanatomic	neuroanatomic	ADJ
fnp-3671	131	12	substrate	substrate	NOUN
fnp-3671	131	13	of	of	ADP
fnp-3671	131	14	this	this	DET
fnp-3671	131	15	aberrant	aberrant	ADJ
fnp-3671	131	16	white	white	ADJ
fnp-3671	131	17	matter	matter	NOUN
fnp-3671	131	18	is	be	AUX
fnp-3671	131	19	fused	fuse	VERB
fnp-3671	131	20	superior	superior	ADJ
fnp-3671	131	21	and	and	CCONJ
fnp-3671	131	22	inferior	inferior	ADJ
fnp-3671	131	23	occipito	occipito	ADJ
fnp-3671	131	24	-	-	PUNCT
fnp-3671	131	25	frontal	frontal	ADJ
fnp-3671	131	26	fasciculi	fasciculus	NOUN
fnp-3671	131	27	,	,	PUNCT
fnp-3671	131	28	with	with	ADP
fnp-3671	131	29	the	the	DET
fnp-3671	131	30	resultant	resultant	NOUN
fnp-3671	131	31	fibers	fiber	NOUN
fnp-3671	131	32	crossing	cross	VERB
fnp-3671	131	33	the	the	DET
fnp-3671	131	34	midline	midline	NOUN
fnp-3671	131	35	.	.	PUNCT
fnp-3671	132	1	while	while	SCONJ
fnp-3671	132	2	the	the	DET
fnp-3671	132	3	etiology	etiology	NOUN
fnp-3671	132	4	of	of	ADP
fnp-3671	132	5	this	this	DET
fnp-3671	132	6	ischemic	ischemic	ADJ
fnp-3671	132	7	-	-	PUNCT
fnp-3671	132	8	like	like	ADJ
fnp-3671	132	9	pathology	pathology	NOUN
fnp-3671	132	10	is	be	AUX
fnp-3671	132	11	unclear	unclear	ADJ
fnp-3671	132	12	,	,	PUNCT
fnp-3671	132	13	the	the	DET
fnp-3671	132	14	literature	literature	NOUN
fnp-3671	132	15	raises	raise	VERB
fnp-3671	132	16	the	the	DET
fnp-3671	132	17	possibility	possibility	NOUN
fnp-3671	132	18	of	of	ADP
fnp-3671	132	19	a	a	DET
fnp-3671	132	20	role	role	NOUN
fnp-3671	132	21	for	for	ADP
fnp-3671	132	22	the	the	DET
fnp-3671	132	23	shh	shh	PROPN
fnp-3671	132	24	pathway	pathway	NOUN
fnp-3671	132	25	.	.	PUNCT
fnp-3671	132	26	  	  	SPACE
fnp-3671	133	1	abstract	abstract	ADJ
fnp-3671	133	2	12	12	NUM
fnp-3671	133	3	free	free	ADJ
fnp-3671	133	4	neuropathol	neuropathol	NOUN
fnp-3671	133	5	2:29:15	2:29:15	NUM
fnp-3671	133	6	brain	brain	NOUN
fnp-3671	133	7	pathology	pathology	NOUN
fnp-3671	133	8	in	in	ADP
fnp-3671	133	9	patients	patient	NOUN
fnp-3671	133	10	with	with	ADP
fnp-3671	133	11	congenital	congenital	ADJ
fnp-3671	133	12	heart	heart	NOUN
fnp-3671	133	13	disease	disease	NOUN
fnp-3671	133	14	murad	murad	NOUN
fnp-3671	133	15	a.	a.	PROPN
fnp-3671	133	16	alturkustani1,2,3	alturkustani1,2,3	PROPN
fnp-3671	133	17	,	,	PUNCT
fnp-3671	133	18	linda	linda	PROPN
fnp-3671	133	19	j.	j.	PROPN
fnp-3671	133	20	szymanski2	szymanski2	PROPN
fnp-3671	133	21	1	1	NUM
fnp-3671	133	22	king	king	PROPN
fnp-3671	133	23	abdulaziz	abdulaziz	PROPN
fnp-3671	133	24	university	university	PROPN
fnp-3671	133	25	,	,	PUNCT
fnp-3671	133	26	jeddah	jeddah	PROPN
fnp-3671	133	27	,	,	PUNCT
fnp-3671	133	28	saudi	saudi	PROPN
fnp-3671	133	29	arabia	arabia	PROPN
fnp-3671	133	30	2	2	NUM
fnp-3671	133	31	children	child	NOUN
fnp-3671	133	32	’s	’s	PART
fnp-3671	133	33	hospital	hospital	NOUN
fnp-3671	133	34	los	los	PROPN
fnp-3671	133	35	angeles	angeles	PROPN
fnp-3671	133	36	,	,	PUNCT
fnp-3671	133	37	los	los	PROPN
fnp-3671	133	38	angeles	angeles	PROPN
fnp-3671	133	39	,	,	PUNCT
fnp-3671	133	40	california	california	PROPN
fnp-3671	133	41	,	,	PUNCT
fnp-3671	133	42	usa	usa	PROPN
fnp-3671	133	43	3	3	NUM
fnp-3671	133	44	western	western	PROPN
fnp-3671	133	45	university	university	PROPN
fnp-3671	133	46	,	,	PUNCT
fnp-3671	133	47	london	london	PROPN
fnp-3671	133	48	,	,	PUNCT
fnp-3671	133	49	ontario	ontario	PROPN
fnp-3671	133	50	,	,	PUNCT
fnp-3671	133	51	canada	canada	PROPN
fnp-3671	133	52	brain	brain	NOUN
fnp-3671	133	53	pathology	pathology	NOUN
fnp-3671	133	54	in	in	ADP
fnp-3671	133	55	patients	patient	NOUN
fnp-3671	133	56	with	with	ADP
fnp-3671	133	57	congenital	congenital	ADJ
fnp-3671	133	58	heart	heart	NOUN
fnp-3671	133	59	disease	disease	NOUN
fnp-3671	133	60	(	(	PUNCT
fnp-3671	133	61	chd	chd	NOUN
fnp-3671	133	62	)	)	PUNCT
fnp-3671	133	63	are	be	AUX
fnp-3671	133	64	associated	associate	VERB
fnp-3671	133	65	with	with	ADP
fnp-3671	133	66	neurodevelopmental	neurodevelopmental	ADJ
fnp-3671	133	67	delay	delay	NOUN
fnp-3671	133	68	.	.	PUNCT
fnp-3671	134	1	imaging	imaging	NOUN
fnp-3671	134	2	studies	study	NOUN
fnp-3671	134	3	support	support	VERB
fnp-3671	134	4	vascular	vascular	ADJ
fnp-3671	134	5	etiology	etiology	NOUN
fnp-3671	134	6	for	for	ADP
fnp-3671	134	7	both	both	CCONJ
fnp-3671	134	8	white	white	ADJ
fnp-3671	134	9	and	and	CCONJ
fnp-3671	134	10	gray	gray	ADJ
fnp-3671	134	11	matter	matter	NOUN
fnp-3671	134	12	lesions	lesion	NOUN
fnp-3671	134	13	.	.	PUNCT
fnp-3671	135	1	in	in	ADP
fnp-3671	135	2	this	this	DET
fnp-3671	135	3	retrospective	retrospective	ADJ
fnp-3671	135	4	study	study	NOUN
fnp-3671	135	5	,	,	PUNCT
fnp-3671	135	6	we	we	PRON
fnp-3671	135	7	describe	describe	VERB
fnp-3671	135	8	the	the	DET
fnp-3671	135	9	pathological	pathological	ADJ
fnp-3671	135	10	changes	change	NOUN
fnp-3671	135	11	in	in	ADP
fnp-3671	135	12	the	the	DET
fnp-3671	135	13	brains	brain	NOUN
fnp-3671	135	14	of	of	ADP
fnp-3671	135	15	patients	patient	NOUN
fnp-3671	135	16	with	with	ADP
fnp-3671	135	17	chd	chd	PROPN
fnp-3671	135	18	.	.	PUNCT
fnp-3671	136	1	the	the	DET
fnp-3671	136	2	last	last	ADJ
fnp-3671	136	3	20	20	NUM
fnp-3671	136	4	autopsy	autopsy	ADJ
fnp-3671	136	5	cases	case	NOUN
fnp-3671	136	6	in	in	ADP
fnp-3671	136	7	patients	patient	NOUN
fnp-3671	136	8	with	with	ADP
fnp-3671	136	9	chd	chd	PROPN
fnp-3671	136	10	at	at	ADP
fnp-3671	136	11	our	our	PRON
fnp-3671	136	12	institution	institution	NOUN
fnp-3671	136	13	were	be	AUX
fnp-3671	136	14	retrieved	retrieve	VERB
fnp-3671	136	15	and	and	CCONJ
fnp-3671	136	16	the	the	DET
fnp-3671	136	17	clinical	clinical	NOUN
fnp-3671	136	18	and	and	CCONJ
fnp-3671	136	19	the	the	DET
fnp-3671	136	20	autopsy	autopsy	ADJ
fnp-3671	136	21	report	report	NOUN
fnp-3671	136	22	were	be	AUX
fnp-3671	136	23	reviewed	review	VERB
fnp-3671	136	24	.	.	PUNCT
fnp-3671	137	1	the	the	DET
fnp-3671	137	2	available	available	ADJ
fnp-3671	137	3	h&e	h&e	PROPN
fnp-3671	137	4	,	,	PUNCT
fnp-3671	137	5	special	special	ADJ
fnp-3671	137	6	,	,	PUNCT
fnp-3671	137	7	and	and	CCONJ
fnp-3671	137	8	immunostains	immunostain	NOUN
fnp-3671	137	9	were	be	AUX
fnp-3671	137	10	evaluated	evaluate	VERB
fnp-3671	137	11	and	and	CCONJ
fnp-3671	137	12	at	at	ADV
fnp-3671	137	13	least	least	ADV
fnp-3671	137	14	one	one	NUM
fnp-3671	137	15	section	section	NOUN
fnp-3671	137	16	from	from	ADP
fnp-3671	137	17	each	each	DET
fnp-3671	137	18	case	case	NOUN
fnp-3671	137	19	was	be	AUX
fnp-3671	137	20	stained	stain	VERB
fnp-3671	137	21	with	with	ADP
fnp-3671	137	22	gfap	gfap	ADJ
fnp-3671	137	23	,	,	PUNCT
fnp-3671	137	24	app	app	ADJ
fnp-3671	137	25	,	,	PUNCT
fnp-3671	137	26	and	and	CCONJ
fnp-3671	137	27	hla	hla	PROPN
fnp-3671	137	28	-	-	PUNCT
fnp-3671	137	29	dr	dr	PROPN
fnp-3671	137	30	.	.	PROPN
fnp-3671	137	31	five	five	NUM
fnp-3671	137	32	control	control	NOUN
fnp-3671	137	33	cases	case	NOUN
fnp-3671	137	34	included	include	VERB
fnp-3671	137	35	telencephalic	telencephalic	NOUN
fnp-3671	137	36	leukoencephalopathy	leukoencephalopathy	NOUN
fnp-3671	137	37	(	(	PUNCT
fnp-3671	137	38	3	3	NUM
fnp-3671	137	39	)	)	PUNCT
fnp-3671	137	40	and	and	CCONJ
fnp-3671	137	41	no	no	DET
fnp-3671	137	42	significant	significant	ADJ
fnp-3671	137	43	pathological	pathological	ADJ
fnp-3671	137	44	changes	change	NOUN
fnp-3671	137	45	(	(	PUNCT
fnp-3671	137	46	2	2	NUM
fnp-3671	137	47	)	)	PUNCT
fnp-3671	137	48	.	.	PUNCT
fnp-3671	138	1	the	the	DET
fnp-3671	138	2	following	follow	VERB
fnp-3671	138	3	histological	histological	ADJ
fnp-3671	138	4	features	feature	NOUN
fnp-3671	138	5	were	be	AUX
fnp-3671	138	6	assessed	assess	VERB
fnp-3671	138	7	:	:	PUNCT
fnp-3671	138	8	necrotic	necrotic	ADJ
fnp-3671	138	9	cells	cell	NOUN
fnp-3671	138	10	in	in	ADP
fnp-3671	138	11	cortex	cortex	NOUN
fnp-3671	138	12	,	,	PUNCT
fnp-3671	138	13	hippocampus	hippocampus	NOUN
fnp-3671	138	14	and	and	CCONJ
fnp-3671	138	15	the	the	DET
fnp-3671	138	16	cerebellum	cerebellum	NOUN
fnp-3671	138	17	;	;	PUNCT
fnp-3671	138	18	app	app	NOUN
fnp-3671	138	19	and	and	CCONJ
fnp-3671	138	20	gfap	gfap	ADJ
fnp-3671	138	21	staining	staining	ADJ
fnp-3671	138	22	pattern	pattern	NOUN
fnp-3671	138	23	,	,	PUNCT
fnp-3671	138	24	and	and	CCONJ
fnp-3671	138	25	presence	presence	NOUN
fnp-3671	138	26	of	of	ADP
fnp-3671	138	27	focal	focal	ADJ
fnp-3671	138	28	lesions	lesion	NOUN
fnp-3671	138	29	and	and	CCONJ
fnp-3671	138	30	amphophilic	amphophilic	ADJ
fnp-3671	138	31	globules	globule	NOUN
fnp-3671	138	32	.	.	PUNCT
fnp-3671	139	1	twenty	twenty	NUM
fnp-3671	139	2	patients	patient	NOUN
fnp-3671	139	3	(	(	PUNCT
fnp-3671	139	4	10	10	NUM
fnp-3671	139	5	males	male	NOUN
fnp-3671	139	6	,	,	PUNCT
fnp-3671	139	7	10	10	NUM
fnp-3671	139	8	females	female	NOUN
fnp-3671	139	9	)	)	PUNCT
fnp-3671	139	10	were	be	AUX
fnp-3671	139	11	identified	identify	VERB
fnp-3671	139	12	with	with	ADP
fnp-3671	139	13	age	age	NOUN
fnp-3671	139	14	range	range	NOUN
fnp-3671	139	15	of	of	ADP
fnp-3671	139	16	2	2	NUM
fnp-3671	139	17	weeks	week	NOUN
fnp-3671	139	18	–	–	PUNCT
fnp-3671	139	19	19	19	NUM
fnp-3671	139	20	years	year	NOUN
fnp-3671	139	21	.	.	PUNCT
fnp-3671	140	1	the	the	DET
fnp-3671	140	2	pathological	pathological	ADJ
fnp-3671	140	3	findings	finding	NOUN
fnp-3671	140	4	are	be	AUX
fnp-3671	140	5	as	as	SCONJ
fnp-3671	140	6	follows	follow	VERB
fnp-3671	140	7	:	:	PUNCT
fnp-3671	140	8	8	8	NUM
fnp-3671	140	9	cases	case	NOUN
fnp-3671	140	10	had	have	VERB
fnp-3671	140	11	changes	change	NOUN
fnp-3671	140	12	consistent	consistent	ADJ
fnp-3671	140	13	with	with	ADP
fnp-3671	140	14	acute	acute	ADJ
fnp-3671	140	15	global	global	ADJ
fnp-3671	140	16	hypoperfusion	hypoperfusion	NOUN
fnp-3671	140	17	,	,	PUNCT
fnp-3671	140	18	5	5	NUM
fnp-3671	140	19	cases	case	NOUN
fnp-3671	140	20	showed	show	VERB
fnp-3671	140	21	features	feature	NOUN
fnp-3671	140	22	consistent	consistent	ADJ
fnp-3671	140	23	with	with	ADP
fnp-3671	140	24	chronic	chronic	ADJ
fnp-3671	140	25	global	global	ADJ
fnp-3671	140	26	hypoperfusion	hypoperfusion	NOUN
fnp-3671	140	27	,	,	PUNCT
fnp-3671	140	28	3	3	NUM
fnp-3671	140	29	cases	case	NOUN
fnp-3671	140	30	showed	show	VERB
fnp-3671	140	31	focal	focal	ADJ
fnp-3671	140	32	white	white	ADJ
fnp-3671	140	33	matter	matter	NOUN
fnp-3671	140	34	lesions	lesion	NOUN
fnp-3671	140	35	(	(	PUNCT
fnp-3671	140	36	1	1	NUM
fnp-3671	140	37	secondary	secondary	ADJ
fnp-3671	140	38	,	,	PUNCT
fnp-3671	140	39	to	to	ADP
fnp-3671	140	40	septic	septic	ADJ
fnp-3671	140	41	emboli	embolus	NOUN
fnp-3671	140	42	)	)	PUNCT
fnp-3671	140	43	,	,	PUNCT
fnp-3671	140	44	4	4	NUM
fnp-3671	140	45	cases	case	NOUN
fnp-3671	140	46	with	with	ADP
fnp-3671	140	47	only	only	ADJ
fnp-3671	140	48	widespread	widespread	ADJ
fnp-3671	140	49	gliosis	gliosis	NOUN
fnp-3671	140	50	,	,	PUNCT
fnp-3671	140	51	one	one	NUM
fnp-3671	140	52	case	case	NOUN
fnp-3671	140	53	with	with	ADP
fnp-3671	140	54	only	only	ADJ
fnp-3671	140	55	old	old	ADJ
fnp-3671	140	56	focal	focal	ADJ
fnp-3671	140	57	neuronal	neuronal	ADJ
fnp-3671	140	58	loss	loss	NOUN
fnp-3671	140	59	in	in	ADP
fnp-3671	140	60	dentate	dentate	ADJ
fnp-3671	140	61	gyrus	gyru	NOUN
fnp-3671	140	62	,	,	PUNCT
fnp-3671	140	63	and	and	CCONJ
fnp-3671	140	64	one	one	NUM
fnp-3671	140	65	with	with	ADP
fnp-3671	140	66	no	no	DET
fnp-3671	140	67	significant	significant	ADJ
fnp-3671	140	68	changes	change	NOUN
fnp-3671	140	69	.	.	PUNCT
fnp-3671	141	1	subarachnoid	subarachnoid	VERB
fnp-3671	141	2	hemorrhages	hemorrhage	NOUN
fnp-3671	141	3	were	be	AUX
fnp-3671	141	4	present	present	ADJ
fnp-3671	141	5	in	in	ADP
fnp-3671	141	6	5	5	NUM
fnp-3671	141	7	cases	case	NOUN
fnp-3671	141	8	and	and	CCONJ
fnp-3671	141	9	germinal	germinal	ADJ
fnp-3671	141	10	matrix	matrix	NOUN
fnp-3671	141	11	hemorrhage	hemorrhage	NOUN
fnp-3671	141	12	in	in	ADP
fnp-3671	141	13	3	3	NUM
fnp-3671	141	14	cases	case	NOUN
fnp-3671	141	15	.	.	PUNCT
fnp-3671	142	1	in	in	ADP
fnp-3671	142	2	conclusion	conclusion	NOUN
fnp-3671	142	3	,	,	PUNCT
fnp-3671	142	4	most	most	ADJ
fnp-3671	142	5	of	of	ADP
fnp-3671	142	6	the	the	DET
fnp-3671	142	7	pathological	pathological	ADJ
fnp-3671	142	8	changes	change	NOUN
fnp-3671	142	9	could	could	AUX
fnp-3671	142	10	be	be	AUX
fnp-3671	142	11	explained	explain	VERB
fnp-3671	142	12	by	by	ADP
fnp-3671	142	13	cerebral	cerebral	ADJ
fnp-3671	142	14	hypoperfusion	hypoperfusion	NOUN
fnp-3671	142	15	and	and	CCONJ
fnp-3671	142	16	better	well	ADJ
fnp-3671	142	17	techniques	technique	NOUN
fnp-3671	142	18	to	to	PART
fnp-3671	142	19	improve	improve	VERB
fnp-3671	142	20	the	the	DET
fnp-3671	142	21	cerebral	cerebral	ADJ
fnp-3671	142	22	perfusion	perfusion	NOUN
fnp-3671	142	23	are	be	AUX
fnp-3671	142	24	warranted	warrant	VERB
fnp-3671	142	25	in	in	ADP
fnp-3671	142	26	the	the	DET
fnp-3671	142	27	management	management	NOUN
fnp-3671	142	28	of	of	ADP
fnp-3671	142	29	these	these	DET
fnp-3671	142	30	patients	patient	NOUN
fnp-3671	142	31	.	.	PUNCT
fnp-3671	142	32	  	  	SPACE
fnp-3671	143	1	abstract	abstract	ADJ
fnp-3671	143	2	13	13	NUM
fnp-3671	143	3	free	free	ADJ
fnp-3671	143	4	neuropathol	neuropathol	NOUN
fnp-3671	143	5	2:29:16	2:29:16	NUM
fnp-3671	143	6	characterizing	characterize	VERB
fnp-3671	143	7	the	the	DET
fnp-3671	143	8	hippocampal	hippocampal	ADJ
fnp-3671	143	9	dentate	dentate	NOUN
fnp-3671	143	10	gyrus	gyrus	NOUN
fnp-3671	143	11	involvement	involvement	NOUN
fnp-3671	143	12	in	in	ADP
fnp-3671	143	13	temporal	temporal	ADJ
fnp-3671	143	14	lobe	lobe	NOUN
fnp-3671	143	15	epilepsy	epilepsy	PROPN
fnp-3671	143	16	carolyn	carolyn	PROPN
fnp-3671	143	17	twible1	twible1	PROPN
fnp-3671	143	18	,	,	PUNCT
fnp-3671	143	19	qi	qi	PROPN
fnp-3671	143	20	zhang1,2	zhang1,2	PROPN
fnp-3671	143	21	1	1	NUM
fnp-3671	143	22	department	department	NOUN
fnp-3671	143	23	of	of	ADP
fnp-3671	143	24	pathology	pathology	NOUN
fnp-3671	143	25	and	and	CCONJ
fnp-3671	143	26	laboratory	laboratory	NOUN
fnp-3671	143	27	medicine	medicine	NOUN
fnp-3671	143	28	,	,	PUNCT
fnp-3671	143	29	schulich	schulich	PROPN
fnp-3671	143	30	school	school	NOUN
fnp-3671	143	31	of	of	ADP
fnp-3671	143	32	medicine	medicine	NOUN
fnp-3671	143	33	and	and	CCONJ
fnp-3671	143	34	dentistry	dentistry	NOUN
fnp-3671	143	35	,	,	PUNCT
fnp-3671	143	36	western	western	ADJ
fnp-3671	143	37	university	university	NOUN
fnp-3671	143	38	,	,	PUNCT
fnp-3671	143	39	london	london	PROPN
fnp-3671	143	40	,	,	PUNCT
fnp-3671	143	41	ontario	ontario	PROPN
fnp-3671	143	42	,	,	PUNCT
fnp-3671	143	43	canada	canada	PROPN
fnp-3671	143	44	2	2	NUM
fnp-3671	143	45	department	department	NOUN
fnp-3671	143	46	of	of	ADP
fnp-3671	143	47	pathology	pathology	NOUN
fnp-3671	143	48	and	and	CCONJ
fnp-3671	143	49	laboratory	laboratory	NOUN
fnp-3671	143	50	medicine	medicine	NOUN
fnp-3671	143	51	,	,	PUNCT
fnp-3671	143	52	london	london	PROPN
fnp-3671	143	53	health	health	PROPN
fnp-3671	143	54	sciences	sciences	PROPN
fnp-3671	143	55	centre	centre	PROPN
fnp-3671	143	56	,	,	PUNCT
fnp-3671	143	57	london	london	PROPN
fnp-3671	143	58	,	,	PUNCT
fnp-3671	143	59	ontario	ontario	PROPN
fnp-3671	143	60	,	,	PUNCT
fnp-3671	143	61	canada	canada	PROPN
fnp-3671	143	62	hippocampal	hippocampal	VERB
fnp-3671	143	63	sclerosis	sclerosis	NOUN
fnp-3671	143	64	(	(	PUNCT
fnp-3671	143	65	hs	hs	X
fnp-3671	143	66	)	)	PUNCT
fnp-3671	143	67	is	be	AUX
fnp-3671	143	68	the	the	DET
fnp-3671	143	69	most	most	ADV
fnp-3671	143	70	common	common	ADJ
fnp-3671	143	71	pathology	pathology	NOUN
fnp-3671	143	72	finding	finding	NOUN
fnp-3671	143	73	for	for	ADP
fnp-3671	143	74	drug	drug	NOUN
fnp-3671	143	75	resistant	resistant	ADJ
fnp-3671	143	76	temporal	temporal	ADJ
fnp-3671	143	77	lobe	lobe	NOUN
fnp-3671	143	78	epilepsy	epilepsy	NOUN
fnp-3671	143	79	(	(	PUNCT
fnp-3671	143	80	tle	tle	ADJ
fnp-3671	143	81	)	)	PUNCT
fnp-3671	143	82	and	and	CCONJ
fnp-3671	143	83	is	be	AUX
fnp-3671	143	84	characterized	characterize	VERB
fnp-3671	143	85	by	by	ADP
fnp-3671	143	86	neuronal	neuronal	ADJ
fnp-3671	143	87	loss	loss	NOUN
fnp-3671	143	88	and	and	CCONJ
fnp-3671	143	89	gliotic	gliotic	ADJ
fnp-3671	143	90	cornu	cornu	NOUN
fnp-3671	143	91	ammonis	ammonis	NOUN
fnp-3671	143	92	.	.	PUNCT
fnp-3671	144	1	nearly	nearly	ADV
fnp-3671	144	2	20	20	NUM
fnp-3671	144	3	%	%	NOUN
fnp-3671	144	4	of	of	ADP
fnp-3671	144	5	surgical	surgical	ADJ
fnp-3671	144	6	specimens	specimen	NOUN
fnp-3671	144	7	from	from	ADP
fnp-3671	144	8	drug	drug	NOUN
fnp-3671	144	9	-	-	PUNCT
fnp-3671	144	10	resistant	resistant	ADJ
fnp-3671	144	11	tle	tle	NOUN
fnp-3671	144	12	surgery	surgery	NOUN
fnp-3671	144	13	contain	contain	VERB
fnp-3671	144	14	“	"	PUNCT
fnp-3671	144	15	normal	normal	ADJ
fnp-3671	144	16	”	"	PUNCT
fnp-3671	144	17	populations	population	NOUN
fnp-3671	144	18	of	of	ADP
fnp-3671	144	19	neurons	neuron	NOUN
fnp-3671	144	20	,	,	PUNCT
fnp-3671	144	21	termed	term	VERB
fnp-3671	144	22	no	no	PROPN
fnp-3671	144	23	-	-	PUNCT
fnp-3671	144	24	hs	hs	ADJ
fnp-3671	144	25	,	,	PUNCT
fnp-3671	144	26	yet	yet	ADV
fnp-3671	144	27	still	still	ADV
fnp-3671	144	28	benefit	benefit	VERB
fnp-3671	144	29	from	from	ADP
fnp-3671	144	30	surgical	surgical	ADJ
fnp-3671	144	31	resection	resection	NOUN
fnp-3671	144	32	.	.	PUNCT
fnp-3671	145	1	this	this	DET
fnp-3671	145	2	observation	observation	NOUN
fnp-3671	145	3	suggests	suggest	VERB
fnp-3671	145	4	a	a	DET
fnp-3671	145	5	neuropathological	neuropathological	ADJ
fnp-3671	145	6	explanation	explanation	NOUN
fnp-3671	145	7	for	for	ADP
fnp-3671	145	8	the	the	DET
fnp-3671	145	9	epileptogenic	epileptogenic	ADJ
fnp-3671	145	10	focus	focus	NOUN
fnp-3671	145	11	in	in	ADP
fnp-3671	145	12	the	the	DET
fnp-3671	145	13	resected	resected	ADJ
fnp-3671	145	14	tissue	tissue	NOUN
fnp-3671	145	15	that	that	PRON
fnp-3671	145	16	is	be	AUX
fnp-3671	145	17	not	not	PART
fnp-3671	145	18	detected	detect	VERB
fnp-3671	145	19	through	through	ADP
fnp-3671	145	20	standard	standard	ADJ
fnp-3671	145	21	diagnostic	diagnostic	ADJ
fnp-3671	145	22	practices	practice	NOUN
fnp-3671	145	23	.	.	PUNCT
fnp-3671	146	1	the	the	DET
fnp-3671	146	2	goals	goal	NOUN
fnp-3671	146	3	of	of	ADP
fnp-3671	146	4	this	this	DET
fnp-3671	146	5	project	project	NOUN
fnp-3671	146	6	are	be	AUX
fnp-3671	146	7	to	to	PART
fnp-3671	146	8	increase	increase	VERB
fnp-3671	146	9	the	the	DET
fnp-3671	146	10	neuropathological	neuropathological	ADJ
fnp-3671	146	11	understanding	understanding	NOUN
fnp-3671	146	12	of	of	ADP
fnp-3671	146	13	drug	drug	NOUN
fnp-3671	146	14	resistant	resistant	ADJ
fnp-3671	146	15	tle	tle	NOUN
fnp-3671	146	16	,	,	PUNCT
fnp-3671	146	17	and	and	CCONJ
fnp-3671	146	18	to	to	PART
fnp-3671	146	19	elucidate	elucidate	VERB
fnp-3671	146	20	the	the	DET
fnp-3671	146	21	structural	structural	ADJ
fnp-3671	146	22	changes	change	NOUN
fnp-3671	146	23	of	of	ADP
fnp-3671	146	24	hs	hs	PROPN
fnp-3671	146	25	and	and	CCONJ
fnp-3671	146	26	no	no	PROPN
fnp-3671	146	27	-	-	PUNCT
fnp-3671	146	28	hs	hs	NOUN
fnp-3671	146	29	,	,	PUNCT
fnp-3671	146	30	focusing	focus	VERB
fnp-3671	146	31	on	on	ADP
fnp-3671	146	32	the	the	DET
fnp-3671	146	33	granule	granule	NOUN
fnp-3671	146	34	cell	cell	NOUN
fnp-3671	146	35	layer	layer	NOUN
fnp-3671	146	36	(	(	PUNCT
fnp-3671	146	37	gcl	gcl	NOUN
fnp-3671	146	38	)	)	PUNCT
fnp-3671	146	39	.	.	PUNCT
fnp-3671	147	1	in	in	ADP
fnp-3671	147	2	this	this	DET
fnp-3671	147	3	study	study	NOUN
fnp-3671	147	4	,	,	PUNCT
fnp-3671	147	5	21	21	NUM
fnp-3671	147	6	tle	tle	VERB
fnp-3671	147	7	surgical	surgical	ADJ
fnp-3671	147	8	resection	resection	NOUN
fnp-3671	147	9	cases	case	NOUN
fnp-3671	147	10	were	be	AUX
fnp-3671	147	11	examined	examine	VERB
fnp-3671	147	12	,	,	PUNCT
fnp-3671	147	13	including	include	VERB
fnp-3671	147	14	14	14	NUM
fnp-3671	147	15	hs	h	NOUN
fnp-3671	147	16	and	and	CCONJ
fnp-3671	147	17	7	7	NUM
fnp-3671	147	18	no	no	DET
fnp-3671	147	19	-	-	PUNCT
fnp-3671	147	20	hs	h	NOUN
fnp-3671	147	21	cases	case	NOUN
fnp-3671	147	22	,	,	PUNCT
fnp-3671	147	23	to	to	PART
fnp-3671	147	24	investigate	investigate	VERB
fnp-3671	147	25	gcl	gcl	PROPN
fnp-3671	147	26	morphometry	morphometry	PROPN
fnp-3671	147	27	.	.	PUNCT
fnp-3671	148	1	information	information	NOUN
fnp-3671	148	2	on	on	ADP
fnp-3671	148	3	histopathological	histopathological	ADJ
fnp-3671	148	4	diagnosis	diagnosis	NOUN
fnp-3671	148	5	and	and	CCONJ
fnp-3671	148	6	post	post	ADJ
fnp-3671	148	7	-	-	ADJ
fnp-3671	148	8	operative	operative	ADJ
fnp-3671	148	9	outcome	outcome	NOUN
fnp-3671	148	10	were	be	AUX
fnp-3671	148	11	collected	collect	VERB
fnp-3671	148	12	.	.	PUNCT
fnp-3671	149	1	the	the	DET
fnp-3671	149	2	digital	digital	ADJ
fnp-3671	149	3	image	image	NOUN
fnp-3671	149	4	analysis	analysis	NOUN
fnp-3671	149	5	software	software	NOUN
fnp-3671	149	6	qupath	qupath	NOUN
fnp-3671	149	7	was	be	AUX
fnp-3671	149	8	used	use	VERB
fnp-3671	149	9	to	to	PART
fnp-3671	149	10	perform	perform	VERB
fnp-3671	149	11	cell	cell	NOUN
fnp-3671	149	12	detection	detection	NOUN
fnp-3671	149	13	analysis	analysis	NOUN
fnp-3671	149	14	on	on	ADP
fnp-3671	149	15	the	the	DET
fnp-3671	149	16	gcl	gcl	PROPN
fnp-3671	149	17	.	.	PROPN
fnp-3671	149	18	measures	measure	NOUN
fnp-3671	149	19	including	include	VERB
fnp-3671	149	20	delaunay	delaunay	PROPN
fnp-3671	149	21	mean	mean	PROPN
fnp-3671	149	22	cell	cell	NOUN
fnp-3671	149	23	density	density	NOUN
fnp-3671	149	24	were	be	AUX
fnp-3671	149	25	analyzed	analyze	VERB
fnp-3671	149	26	.	.	PUNCT
fnp-3671	150	1	hs	hs	PROPN
fnp-3671	150	2	patients	patient	NOUN
fnp-3671	150	3	show	show	VERB
fnp-3671	150	4	a	a	DET
fnp-3671	150	5	significant	significant	ADJ
fnp-3671	150	6	increase	increase	NOUN
fnp-3671	150	7	in	in	ADP
fnp-3671	150	8	granule	granule	NOUN
fnp-3671	150	9	cell	cell	NOUN
fnp-3671	150	10	spacing	space	VERB
fnp-3671	150	11	and	and	CCONJ
fnp-3671	150	12	decrease	decrease	NOUN
fnp-3671	150	13	in	in	ADP
fnp-3671	150	14	granule	granule	NOUN
fnp-3671	150	15	cell	cell	NOUN
fnp-3671	150	16	density	density	NOUN
fnp-3671	150	17	within	within	ADP
fnp-3671	150	18	the	the	DET
fnp-3671	150	19	gcl	gcl	NOUN
fnp-3671	150	20	compared	compare	VERB
fnp-3671	150	21	to	to	ADP
fnp-3671	150	22	no	no	DET
fnp-3671	150	23	-	-	PUNCT
fnp-3671	150	24	hs	hs	NOUN
fnp-3671	150	25	patients	patient	NOUN
fnp-3671	150	26	.	.	PUNCT
fnp-3671	151	1	regardless	regardless	ADV
fnp-3671	151	2	of	of	ADP
fnp-3671	151	3	the	the	DET
fnp-3671	151	4	histological	histological	ADJ
fnp-3671	151	5	diagnosis	diagnosis	NOUN
fnp-3671	151	6	,	,	PUNCT
fnp-3671	151	7	patients	patient	NOUN
fnp-3671	151	8	who	who	PRON
fnp-3671	151	9	achieved	achieve	VERB
fnp-3671	151	10	seizure	seizure	NOUN
fnp-3671	151	11	freedom	freedom	NOUN
fnp-3671	151	12	post	post	NOUN
fnp-3671	151	13	-	-	ADJ
fnp-3671	151	14	operatively	operatively	ADV
fnp-3671	151	15	demonstrated	demonstrate	VERB
fnp-3671	151	16	an	an	DET
fnp-3671	151	17	increase	increase	NOUN
fnp-3671	151	18	in	in	ADP
fnp-3671	151	19	granule	granule	NOUN
fnp-3671	151	20	cell	cell	NOUN
fnp-3671	151	21	spacing	space	VERB
fnp-3671	151	22	and	and	CCONJ
fnp-3671	151	23	decrease	decrease	NOUN
fnp-3671	151	24	in	in	ADP
fnp-3671	151	25	granule	granule	NOUN
fnp-3671	151	26	cell	cell	NOUN
fnp-3671	151	27	density	density	NOUN
fnp-3671	151	28	in	in	ADP
fnp-3671	151	29	comparison	comparison	NOUN
fnp-3671	151	30	to	to	ADP
fnp-3671	151	31	those	those	PRON
fnp-3671	151	32	who	who	PRON
fnp-3671	151	33	did	do	AUX
fnp-3671	151	34	not	not	PART
fnp-3671	151	35	achieve	achieve	VERB
fnp-3671	151	36	seizure	seizure	NOUN
fnp-3671	151	37	freedom	freedom	NOUN
fnp-3671	151	38	post	post	NOUN
fnp-3671	151	39	-	-	ADJ
fnp-3671	151	40	operatively	operatively	ADV
fnp-3671	151	41	.	.	PUNCT
fnp-3671	152	1	hs	hs	PROPN
fnp-3671	152	2	and	and	CCONJ
fnp-3671	152	3	no	no	PROPN
fnp-3671	152	4	-	-	PUNCT
fnp-3671	152	5	hs	hs	NOUN
fnp-3671	152	6	diagnosis	diagnosis	NOUN
fnp-3671	152	7	groups	group	NOUN
fnp-3671	152	8	have	have	VERB
fnp-3671	152	9	diseaseand	diseaseand	NOUN
fnp-3671	152	10	post	post	ADJ
fnp-3671	152	11	-	-	ADJ
fnp-3671	152	12	operative	operative	ADJ
fnp-3671	152	13	outcome	outcome	NOUN
fnp-3671	152	14	dependent	dependent	ADJ
fnp-3671	152	15	morphometry	morphometry	NOUN
fnp-3671	152	16	differences	difference	NOUN
fnp-3671	152	17	.	.	PUNCT
fnp-3671	153	1	the	the	DET
fnp-3671	153	2	post	post	ADJ
fnp-3671	153	3	-	-	ADJ
fnp-3671	153	4	operative	operative	ADJ
fnp-3671	153	5	outcome	outcome	NOUN
fnp-3671	153	6	dependent	dependent	ADJ
fnp-3671	153	7	morphometry	morphometry	NOUN
fnp-3671	153	8	observed	observe	VERB
fnp-3671	153	9	in	in	ADP
fnp-3671	153	10	hs	hs	PROPN
fnp-3671	153	11	and	and	CCONJ
fnp-3671	153	12	no	no	PROPN
fnp-3671	153	13	-	-	PUNCT
fnp-3671	153	14	hs	hs	PROPN
fnp-3671	153	15	patients	patient	NOUN
fnp-3671	153	16	presents	present	VERB
fnp-3671	153	17	a	a	DET
fnp-3671	153	18	potential	potential	ADJ
fnp-3671	153	19	additional	additional	ADJ
fnp-3671	153	20	method	method	NOUN
fnp-3671	153	21	to	to	PART
fnp-3671	153	22	evaluate	evaluate	VERB
fnp-3671	153	23	post	post	ADJ
fnp-3671	153	24	-	-	ADJ
fnp-3671	153	25	operative	operative	ADJ
fnp-3671	153	26	prognosis	prognosis	NOUN
fnp-3671	153	27	for	for	ADP
fnp-3671	153	28	tle	tle	ADJ
fnp-3671	153	29	surgical	surgical	ADJ
fnp-3671	153	30	-	-	PUNCT
fnp-3671	153	31	resection	resection	NOUN
fnp-3671	153	32	patients	patient	NOUN
fnp-3671	153	33	.	.	PUNCT
fnp-3671	153	34	  	  	SPACE
fnp-3671	154	1	abstract	abstract	ADJ
fnp-3671	154	2	14	14	NUM
fnp-3671	154	3	free	free	ADJ
fnp-3671	154	4	neuropathol	neuropathol	NOUN
fnp-3671	154	5	2:29:17	2:29:17	NUM
fnp-3671	154	6	deep	deep	ADJ
fnp-3671	154	7	learning	learning	NOUN
fnp-3671	154	8	approaches	approach	NOUN
fnp-3671	154	9	to	to	ADP
fnp-3671	154	10	deciphering	decipher	VERB
fnp-3671	154	11	intra	intra	ADJ
fnp-3671	154	12	-	-	ADJ
fnp-3671	154	13	tumoural	tumoural	ADJ
fnp-3671	154	14	heterogeneity	heterogeneity	NOUN
fnp-3671	154	15	in	in	ADP
fnp-3671	154	16	glioblastoma	glioblastoma	NOUN
fnp-3671	154	17	anglin	anglin	PROPN
fnp-3671	154	18	dent1	dent1	PROPN
fnp-3671	154	19	,	,	PUNCT
fnp-3671	154	20	brian	brian	PROPN
fnp-3671	154	21	lam1	lam1	PROPN
fnp-3671	154	22	,	,	PUNCT
fnp-3671	154	23	kevin	kevin	PROPN
fnp-3671	154	24	faust1	faust1	PROPN
fnp-3671	154	25	,	,	PUNCT
fnp-3671	154	26	alberto	alberto	PROPN
fnp-3671	154	27	j.	j.	PROPN
fnp-3671	154	28	leon3	leon3	PROPN
fnp-3671	154	29	,	,	PUNCT
fnp-3671	154	30	phedias	phedia	NOUN
fnp-3671	154	31	diamandis1	diamandis1	NOUN
fnp-3671	154	32	1	1	NUM
fnp-3671	154	33	princess	princess	PROPN
fnp-3671	154	34	margaret	margaret	PROPN
fnp-3671	154	35	cancer	cancer	PROPN
fnp-3671	154	36	centre	centre	PROPN
fnp-3671	154	37	,	,	PUNCT
fnp-3671	154	38	university	university	NOUN
fnp-3671	154	39	health	health	NOUN
fnp-3671	154	40	network	network	NOUN
fnp-3671	154	41	,	,	PUNCT
fnp-3671	154	42	toronto	toronto	PROPN
fnp-3671	154	43	,	,	PUNCT
fnp-3671	154	44	ontario	ontario	PROPN
fnp-3671	154	45	,	,	PUNCT
fnp-3671	154	46	canada	canada	PROPN
fnp-3671	154	47	background	background	NOUN
fnp-3671	154	48	:	:	PUNCT
fnp-3671	154	49	emerging	emerge	VERB
fnp-3671	154	50	evidence	evidence	NOUN
fnp-3671	154	51	strongly	strongly	ADV
fnp-3671	154	52	implicates	implicate	VERB
fnp-3671	154	53	intra	intra	ADJ
fnp-3671	154	54	-	-	ADJ
fnp-3671	154	55	tumoral	tumoral	ADJ
fnp-3671	154	56	heterogeneous	heterogeneous	ADJ
fnp-3671	154	57	biology	biology	NOUN
fnp-3671	154	58	in	in	ADP
fnp-3671	154	59	treatment	treatment	NOUN
fnp-3671	154	60	resistance	resistance	NOUN
fnp-3671	154	61	and	and	CCONJ
fnp-3671	154	62	disease	disease	NOUN
fnp-3671	154	63	progression	progression	NOUN
fnp-3671	154	64	across	across	ADP
fnp-3671	154	65	many	many	ADJ
fnp-3671	154	66	cancer	cancer	NOUN
fnp-3671	154	67	types	type	NOUN
fnp-3671	154	68	(	(	PUNCT
fnp-3671	154	69	1	1	NUM
fnp-3671	154	70	)	)	PUNCT
fnp-3671	154	71	.	.	PUNCT
fnp-3671	155	1	using	use	VERB
fnp-3671	155	2	glioblastoma	glioblastoma	NOUN
fnp-3671	155	3	(	(	PUNCT
fnp-3671	155	4	gbm	gbm	PROPN
fnp-3671	155	5	)	)	PUNCT
fnp-3671	155	6	as	as	ADP
fnp-3671	155	7	a	a	DET
fnp-3671	155	8	prototype	prototype	NOUN
fnp-3671	155	9	,	,	PUNCT
fnp-3671	155	10	i	i	PRON
fnp-3671	155	11	have	have	AUX
fnp-3671	155	12	aimed	aim	VERB
fnp-3671	155	13	to	to	PART
fnp-3671	155	14	leverage	leverage	VERB
fnp-3671	155	15	the	the	DET
fnp-3671	155	16	computational	computational	ADJ
fnp-3671	155	17	power	power	NOUN
fnp-3671	155	18	of	of	ADP
fnp-3671	155	19	artificial	artificial	ADJ
fnp-3671	155	20	intelligence	intelligence	NOUN
fnp-3671	155	21	(	(	PUNCT
fnp-3671	155	22	ai	ai	NOUN
fnp-3671	155	23	)	)	PUNCT
fnp-3671	155	24	and	and	CCONJ
fnp-3671	155	25	deep	deep	ADJ
fnp-3671	155	26	learning	learning	NOUN
fnp-3671	155	27	(	(	PUNCT
fnp-3671	155	28	2	2	NUM
fnp-3671	155	29	)	)	PUNCT
fnp-3671	155	30	to	to	PART
fnp-3671	155	31	develop	develop	VERB
fnp-3671	155	32	an	an	DET
fnp-3671	155	33	autonomous	autonomous	ADJ
fnp-3671	155	34	workflow	workflow	NOUN
fnp-3671	155	35	for	for	ADP
fnp-3671	155	36	the	the	DET
fnp-3671	155	37	objective	objective	ADJ
fnp-3671	155	38	definition	definition	NOUN
fnp-3671	155	39	and	and	CCONJ
fnp-3671	155	40	quantification	quantification	NOUN
fnp-3671	155	41	of	of	ADP
fnp-3671	155	42	biologically	biologically	ADV
fnp-3671	155	43	distinct	distinct	ADJ
fnp-3671	155	44	tumour	tumour	ADJ
fnp-3671	155	45	subpopulations	subpopulation	NOUN
fnp-3671	155	46	.	.	PUNCT
fnp-3671	156	1	objectives	objective	NOUN
fnp-3671	156	2	:	:	PUNCT
fnp-3671	156	3	i	i	PRON
fnp-3671	156	4	hypothesize	hypothesize	VERB
fnp-3671	156	5	that	that	PRON
fnp-3671	156	6	ai	ai	VERB
fnp-3671	156	7	-	-	PUNCT
fnp-3671	156	8	defined	define	VERB
fnp-3671	156	9	tumoral	tumoral	ADJ
fnp-3671	156	10	clusters	cluster	NOUN
fnp-3671	156	11	predict	predict	VERB
fnp-3671	156	12	spatially	spatially	ADV
fnp-3671	156	13	distinct	distinct	ADJ
fnp-3671	156	14	molecular	molecular	ADJ
fnp-3671	156	15	profiles	profile	NOUN
fnp-3671	156	16	and	and	CCONJ
fnp-3671	156	17	therapeutic	therapeutic	ADJ
fnp-3671	156	18	targets	target	NOUN
fnp-3671	156	19	.	.	PUNCT
fnp-3671	157	1	methods	method	NOUN
fnp-3671	157	2	:	:	PUNCT
fnp-3671	157	3	i	i	PRON
fnp-3671	157	4	apply	apply	VERB
fnp-3671	157	5	our	our	PRON
fnp-3671	157	6	developed	develop	VERB
fnp-3671	157	7	image	image	NOUN
fnp-3671	157	8	clustering	cluster	VERB
fnp-3671	157	9	workflows	workflow	NOUN
fnp-3671	157	10	(	(	PUNCT
fnp-3671	157	11	3	3	NUM
fnp-3671	157	12	)	)	PUNCT
fnp-3671	157	13	to	to	PART
fnp-3671	157	14	quantify	quantify	VERB
fnp-3671	157	15	ai	ai	VERB
fnp-3671	157	16	-	-	PUNCT
fnp-3671	157	17	defined	define	VERB
fnp-3671	157	18	subregions	subregion	NOUN
fnp-3671	157	19	within	within	ADP
fnp-3671	157	20	a	a	DET
fnp-3671	157	21	clinical	clinical	ADJ
fnp-3671	157	22	cohort	cohort	NOUN
fnp-3671	157	23	of	of	ADP
fnp-3671	157	24	10	10	NUM
fnp-3671	157	25	gbm	gbm	NOUN
fnp-3671	157	26	patient	patient	ADJ
fnp-3671	157	27	tumors	tumor	NOUN
fnp-3671	157	28	and	and	CCONJ
fnp-3671	157	29	use	use	VERB
fnp-3671	157	30	laser	laser	NOUN
fnp-3671	157	31	capture	capture	NOUN
fnp-3671	157	32	microdissection	microdissection	NOUN
fnp-3671	157	33	and	and	CCONJ
fnp-3671	157	34	mass	mass	ADJ
fnp-3671	157	35	spectrometry	spectrometry	NOUN
fnp-3671	157	36	-	-	PUNCT
fnp-3671	157	37	based	base	VERB
fnp-3671	157	38	proteomics	proteomic	NOUN
fnp-3671	157	39	to	to	PART
fnp-3671	157	40	address	address	VERB
fnp-3671	157	41	if	if	SCONJ
fnp-3671	157	42	ai	ai	VERB
fnp-3671	157	43	-	-	PUNCT
fnp-3671	157	44	defined	define	VERB
fnp-3671	157	45	subregions	subregion	NOUN
fnp-3671	157	46	show	show	VERB
fnp-3671	157	47	intra	intra	ADJ
fnp-3671	157	48	-	-	ADJ
fnp-3671	157	49	tumoral	tumoral	ADJ
fnp-3671	157	50	molecular	molecular	ADJ
fnp-3671	157	51	variation	variation	NOUN
fnp-3671	157	52	.	.	PUNCT
fnp-3671	158	1	further	far	ADV
fnp-3671	158	2	,	,	PUNCT
fnp-3671	158	3	i	i	PRON
fnp-3671	158	4	leverage	leverage	VERB
fnp-3671	158	5	existing	exist	VERB
fnp-3671	158	6	pharmacogenomic	pharmacogenomic	ADJ
fnp-3671	158	7	databases	database	NOUN
fnp-3671	158	8	(	(	PUNCT
fnp-3671	158	9	4	4	NUM
fnp-3671	158	10	)	)	PUNCT
fnp-3671	158	11	and	and	CCONJ
fnp-3671	158	12	carry	carry	VERB
fnp-3671	158	13	out	out	ADP
fnp-3671	158	14	drug	drug	NOUN
fnp-3671	158	15	sensitivity	sensitivity	NOUN
fnp-3671	158	16	and	and	CCONJ
fnp-3671	158	17	transcriptional	transcriptional	NOUN
fnp-3671	158	18	clustering	clustering	NOUN
fnp-3671	158	19	to	to	PART
fnp-3671	158	20	define	define	VERB
fnp-3671	158	21	biomarkers	biomarker	NOUN
fnp-3671	158	22	and	and	CCONJ
fnp-3671	158	23	validate	validate	VERB
fnp-3671	158	24	their	their	PRON
fnp-3671	158	25	intra	intra	ADJ
fnp-3671	158	26	-	-	ADJ
fnp-3671	158	27	tumoral	tumoral	ADJ
fnp-3671	158	28	expression	expression	NOUN
fnp-3671	158	29	in	in	ADP
fnp-3671	158	30	my	my	PRON
fnp-3671	158	31	clinical	clinical	ADJ
fnp-3671	158	32	gbm	gbm	NOUN
fnp-3671	158	33	cohort	cohort	NOUN
fnp-3671	158	34	.	.	PUNCT
fnp-3671	159	1	results	result	NOUN
fnp-3671	159	2	:	:	PUNCT
fnp-3671	159	3	preliminary	preliminary	ADJ
fnp-3671	159	4	data	datum	NOUN
fnp-3671	159	5	shows	show	VERB
fnp-3671	159	6	that	that	SCONJ
fnp-3671	159	7	region	region	NOUN
fnp-3671	159	8	-	-	PUNCT
fnp-3671	159	9	to	to	ADP
fnp-3671	159	10	-	-	PUNCT
fnp-3671	159	11	region	region	NOUN
fnp-3671	159	12	heterogeneity	heterogeneity	NOUN
fnp-3671	159	13	can	can	AUX
fnp-3671	159	14	be	be	AUX
fnp-3671	159	15	found	find	VERB
fnp-3671	159	16	in	in	ADP
fnp-3671	159	17	idh	idh	ADJ
fnp-3671	159	18	wild	wild	ADJ
fnp-3671	159	19	-	-	PUNCT
fnp-3671	159	20	type	type	NOUN
fnp-3671	159	21	gbm	gbm	NOUN
fnp-3671	159	22	using	use	VERB
fnp-3671	159	23	our	our	PRON
fnp-3671	159	24	unbiased	unbiased	ADJ
fnp-3671	159	25	omics	omic	NOUN
fnp-3671	159	26	approach	approach	NOUN
fnp-3671	159	27	,	,	PUNCT
fnp-3671	159	28	in	in	ADP
fnp-3671	159	29	addition	addition	NOUN
fnp-3671	159	30	to	to	ADP
fnp-3671	159	31	predicting	predict	VERB
fnp-3671	159	32	different	different	ADJ
fnp-3671	159	33	pharmacogenomic	pharmacogenomic	ADJ
fnp-3671	159	34	sensitivities	sensitivity	NOUN
fnp-3671	159	35	.	.	PUNCT
fnp-3671	160	1	conclusions	conclusion	NOUN
fnp-3671	160	2	:	:	PUNCT
fnp-3671	160	3	this	this	DET
fnp-3671	160	4	project	project	NOUN
fnp-3671	160	5	aims	aim	VERB
fnp-3671	160	6	to	to	PART
fnp-3671	160	7	develop	develop	VERB
fnp-3671	160	8	the	the	DET
fnp-3671	160	9	first	first	ADJ
fnp-3671	160	10	ai	ai	ADJ
fnp-3671	160	11	-	-	PUNCT
fnp-3671	160	12	driven	drive	VERB
fnp-3671	160	13	tool	tool	NOUN
fnp-3671	160	14	to	to	PART
fnp-3671	160	15	guide	guide	VERB
fnp-3671	160	16	the	the	DET
fnp-3671	160	17	routine	routine	ADJ
fnp-3671	160	18	and	and	CCONJ
fnp-3671	160	19	systematic	systematic	ADJ
fnp-3671	160	20	molecular	molecular	ADJ
fnp-3671	160	21	analysis	analysis	NOUN
fnp-3671	160	22	of	of	ADP
fnp-3671	160	23	spatial	spatial	ADJ
fnp-3671	160	24	morphogenomic	morphogenomic	ADJ
fnp-3671	160	25	heterogeneity	heterogeneity	NOUN
fnp-3671	160	26	.	.	PUNCT
fnp-3671	161	1	further	far	ADV
fnp-3671	161	2	,	,	PUNCT
fnp-3671	161	3	this	this	DET
fnp-3671	161	4	tool	tool	NOUN
fnp-3671	161	5	may	may	AUX
fnp-3671	161	6	have	have	VERB
fnp-3671	161	7	the	the	DET
fnp-3671	161	8	potential	potential	NOUN
fnp-3671	161	9	to	to	PART
fnp-3671	161	10	provide	provide	VERB
fnp-3671	161	11	novel	novel	ADJ
fnp-3671	161	12	approaches	approach	NOUN
fnp-3671	161	13	for	for	ADP
fnp-3671	161	14	personalized	personalized	ADJ
fnp-3671	161	15	care	care	NOUN
fnp-3671	161	16	by	by	ADP
fnp-3671	161	17	selecting	select	VERB
fnp-3671	161	18	drug	drug	NOUN
fnp-3671	161	19	combinations	combination	NOUN
fnp-3671	161	20	that	that	PRON
fnp-3671	161	21	target	target	VERB
fnp-3671	161	22	a	a	DET
fnp-3671	161	23	larger	large	ADJ
fnp-3671	161	24	fraction	fraction	NOUN
fnp-3671	161	25	of	of	ADP
fnp-3671	161	26	a	a	DET
fnp-3671	161	27	tumor	tumor	NOUN
fnp-3671	161	28	’s	’s	PART
fnp-3671	161	29	true	true	ADJ
fnp-3671	161	30	biology	biology	NOUN
fnp-3671	161	31	.	.	PUNCT
fnp-3671	161	32	  	  	SPACE
fnp-3671	162	1	abstract	abstract	ADJ
fnp-3671	162	2	15	15	NUM
fnp-3671	162	3	free	free	ADJ
fnp-3671	162	4	neuropathol	neuropathol	NOUN
fnp-3671	162	5	2:29:18	2:29:18	NUM
fnp-3671	162	6	integrating	integrate	VERB
fnp-3671	162	7	morphologic	morphologic	ADJ
fnp-3671	162	8	and	and	CCONJ
fnp-3671	162	9	molecular	molecular	ADJ
fnp-3671	162	10	histopathological	histopathological	ADJ
fnp-3671	162	11	features	feature	NOUN
fnp-3671	162	12	through	through	ADP
fnp-3671	162	13	whole	whole	ADJ
fnp-3671	162	14	slide	slide	NOUN
fnp-3671	162	15	image	image	NOUN
fnp-3671	162	16	registration	registration	NOUN
fnp-3671	162	17	and	and	CCONJ
fnp-3671	162	18	deep	deep	ADJ
fnp-3671	162	19	learning	learn	VERB
fnp-3671	162	20	michael	michael	PROPN
fnp-3671	162	21	k.	k.	PROPN
fnp-3671	162	22	lee1	lee1	PROPN
fnp-3671	162	23	,	,	PUNCT
fnp-3671	162	24	kevin	kevin	PROPN
fnp-3671	162	25	faust2,3	faust2,3	PROPN
fnp-3671	162	26	,	,	PUNCT
fnp-3671	162	27	anglin	anglin	PROPN
fnp-3671	162	28	dent1	dent1	PROPN
fnp-3671	162	29	,	,	PUNCT
fnp-3671	162	30	clare	clare	PROPN
fnp-3671	162	31	fiala3	fiala3	PROPN
fnp-3671	162	32	,	,	PUNCT
fnp-3671	162	33	alessia	alessia	PROPN
fnp-3671	162	34	portante1	portante1	PROPN
fnp-3671	162	35	,	,	PUNCT
fnp-3671	162	36	madhu	madhu	PROPN
fnp-3671	162	37	rabindranath1	rabindranath1	PROPN
fnp-3671	162	38	,	,	PUNCT
fnp-3671	162	39	noor	noor	PROPN
fnp-3671	162	40	alsafwani3,4	alsafwani3,4	PROPN
fnp-3671	162	41	,	,	PUNCT
fnp-3671	162	42	andrew	andrew	PROPN
fnp-3671	162	43	gao1,3	gao1,3	PROPN
fnp-3671	162	44	,	,	PUNCT
fnp-3671	162	45	ugljesa	ugljesa	PROPN
fnp-3671	162	46	djuric5	djuric5	PROPN
fnp-3671	162	47	,	,	PUNCT
fnp-3671	162	48	phedias	phedia	NOUN
fnp-3671	162	49	diamandis1,3,5,6	diamandis1,3,5,6	PROPN
fnp-3671	162	50	1	1	NUM
fnp-3671	162	51	department	department	NOUN
fnp-3671	162	52	of	of	ADP
fnp-3671	162	53	laboratory	laboratory	NOUN
fnp-3671	162	54	medicine	medicine	NOUN
fnp-3671	162	55	and	and	CCONJ
fnp-3671	162	56	pathobiology	pathobiology	NOUN
fnp-3671	162	57	,	,	PUNCT
fnp-3671	162	58	university	university	PROPN
fnp-3671	162	59	of	of	ADP
fnp-3671	162	60	toronto	toronto	PROPN
fnp-3671	162	61	,	,	PUNCT
fnp-3671	162	62	toronto	toronto	PROPN
fnp-3671	162	63	,	,	PUNCT
fnp-3671	162	64	ontario	ontario	PROPN
fnp-3671	162	65	,	,	PUNCT
fnp-3671	162	66	canada	canada	PROPN
fnp-3671	162	67	2	2	NUM
fnp-3671	162	68	department	department	NOUN
fnp-3671	162	69	of	of	ADP
fnp-3671	162	70	computer	computer	NOUN
fnp-3671	162	71	science	science	NOUN
fnp-3671	162	72	,	,	PUNCT
fnp-3671	162	73	university	university	PROPN
fnp-3671	162	74	of	of	ADP
fnp-3671	162	75	toronto	toronto	PROPN
fnp-3671	162	76	,	,	PUNCT
fnp-3671	162	77	toronto	toronto	PROPN
fnp-3671	162	78	,	,	PUNCT
fnp-3671	162	79	ontario	ontario	PROPN
fnp-3671	162	80	,	,	PUNCT
fnp-3671	162	81	canada	canada	PROPN
fnp-3671	162	82	3	3	NUM
fnp-3671	162	83	laboratory	laboratory	NOUN
fnp-3671	162	84	medicine	medicine	NOUN
fnp-3671	162	85	program	program	NOUN
fnp-3671	162	86	,	,	PUNCT
fnp-3671	162	87	department	department	NOUN
fnp-3671	162	88	of	of	ADP
fnp-3671	162	89	pathology	pathology	PROPN
fnp-3671	162	90	,	,	PUNCT
fnp-3671	162	91	university	university	NOUN
fnp-3671	162	92	health	health	NOUN
fnp-3671	162	93	network	network	NOUN
fnp-3671	162	94	,	,	PUNCT
fnp-3671	162	95	toronto	toronto	PROPN
fnp-3671	162	96	,	,	PUNCT
fnp-3671	162	97	ontario	ontario	PROPN
fnp-3671	162	98	,	,	PUNCT
fnp-3671	162	99	canada	canada	PROPN
fnp-3671	162	100	4	4	NUM
fnp-3671	162	101	department	department	PROPN
fnp-3671	162	102	of	of	ADP
fnp-3671	162	103	pathology	pathology	PROPN
fnp-3671	162	104	,	,	PUNCT
fnp-3671	162	105	college	college	NOUN
fnp-3671	162	106	of	of	ADP
fnp-3671	162	107	medicine	medicine	NOUN
fnp-3671	162	108	,	,	PUNCT
fnp-3671	162	109	imam	imam	PROPN
fnp-3671	162	110	abdulrahman	abdulrahman	PROPN
fnp-3671	162	111	bin	bin	PROPN
fnp-3671	162	112	faisal	faisal	PROPN
fnp-3671	162	113	university	university	PROPN
fnp-3671	162	114	,	,	PUNCT
fnp-3671	162	115	dammam	dammam	PROPN
fnp-3671	162	116	,	,	PUNCT
fnp-3671	162	117	saudi	saudi	PROPN
fnp-3671	162	118	arabia	arabia	PROPN
fnp-3671	162	119	5	5	NUM
fnp-3671	162	120	princess	princess	PROPN
fnp-3671	162	121	margaret	margaret	PROPN
fnp-3671	162	122	cancer	cancer	PROPN
fnp-3671	162	123	centre	centre	PROPN
fnp-3671	162	124	,	,	PUNCT
fnp-3671	162	125	toronto	toronto	PROPN
fnp-3671	162	126	,	,	PUNCT
fnp-3671	162	127	ontario	ontario	PROPN
fnp-3671	162	128	,	,	PUNCT
fnp-3671	162	129	canada	canada	PROPN
fnp-3671	162	130	6	6	NUM
fnp-3671	162	131	department	department	NOUN
fnp-3671	162	132	of	of	ADP
fnp-3671	162	133	medical	medical	ADJ
fnp-3671	162	134	biophysics	biophysic	NOUN
fnp-3671	162	135	,	,	PUNCT
fnp-3671	162	136	university	university	PROPN
fnp-3671	162	137	of	of	ADP
fnp-3671	162	138	toronto	toronto	PROPN
fnp-3671	162	139	,	,	PUNCT
fnp-3671	162	140	toronto	toronto	PROPN
fnp-3671	162	141	,	,	PUNCT
fnp-3671	162	142	ontario	ontario	PROPN
fnp-3671	162	143	,	,	PUNCT
fnp-3671	162	144	canada	canada	PROPN
fnp-3671	162	145	background	background	NOUN
fnp-3671	162	146	and	and	CCONJ
fnp-3671	162	147	objective	objective	ADJ
fnp-3671	162	148	:	:	PUNCT
fnp-3671	162	149	despite	despite	SCONJ
fnp-3671	162	150	recent	recent	ADJ
fnp-3671	162	151	innovations	innovation	NOUN
fnp-3671	162	152	in	in	ADP
fnp-3671	162	153	deep	deep	ADJ
fnp-3671	162	154	learning	learning	NOUN
fnp-3671	162	155	,	,	PUNCT
fnp-3671	162	156	integrating	integrate	VERB
fnp-3671	162	157	histomorphologic	histomorphologic	ADJ
fnp-3671	162	158	and	and	CCONJ
fnp-3671	162	159	molecular	molecular	ADJ
fnp-3671	162	160	information	information	NOUN
fnp-3671	162	161	found	find	VERB
fnp-3671	162	162	on	on	ADP
fnp-3671	162	163	respective	respective	ADJ
fnp-3671	162	164	h&e	h&e	PROPN
fnp-3671	162	165	and	and	CCONJ
fnp-3671	162	166	ihc	ihc	NOUN
fnp-3671	162	167	-	-	PUNCT
fnp-3671	162	168	stained	stain	VERB
fnp-3671	162	169	tissue	tissue	NOUN
fnp-3671	162	170	sections	section	NOUN
fnp-3671	162	171	still	still	ADV
fnp-3671	162	172	remains	remain	VERB
fnp-3671	162	173	a	a	DET
fnp-3671	162	174	challenge	challenge	NOUN
fnp-3671	162	175	.	.	PUNCT
fnp-3671	163	1	while	while	SCONJ
fnp-3671	163	2	human	human	ADJ
fnp-3671	163	3	observers	observer	NOUN
fnp-3671	163	4	can	can	AUX
fnp-3671	163	5	easily	easily	ADV
fnp-3671	163	6	align	align	VERB
fnp-3671	163	7	these	these	DET
fnp-3671	163	8	different	different	ADJ
fnp-3671	163	9	tissue	tissue	NOUN
fnp-3671	163	10	sections	section	NOUN
fnp-3671	163	11	,	,	PUNCT
fnp-3671	163	12	routine	routine	ADJ
fnp-3671	163	13	computational	computational	ADJ
fnp-3671	163	14	approaches	approach	NOUN
fnp-3671	163	15	for	for	ADP
fnp-3671	163	16	image	image	NOUN
fnp-3671	163	17	registration	registration	NOUN
fnp-3671	163	18	of	of	ADP
fnp-3671	163	19	giga	giga	ADJ
fnp-3671	163	20	-	-	PUNCT
fnp-3671	163	21	byte	byte	NOUN
fnp-3671	163	22	sized	sized	ADJ
fnp-3671	163	23	wsis	wsis	NOUN
fnp-3671	163	24	are	be	AUX
fnp-3671	163	25	still	still	ADV
fnp-3671	163	26	needed	need	VERB
fnp-3671	163	27	.	.	PUNCT
fnp-3671	164	1	here	here	ADV
fnp-3671	164	2	,	,	PUNCT
fnp-3671	164	3	we	we	PRON
fnp-3671	164	4	aim	aim	VERB
fnp-3671	164	5	to	to	PART
fnp-3671	164	6	address	address	VERB
fnp-3671	164	7	this	this	DET
fnp-3671	164	8	issue	issue	NOUN
fnp-3671	164	9	by	by	ADP
fnp-3671	164	10	incorporating	incorporate	VERB
fnp-3671	164	11	another	another	DET
fnp-3671	164	12	computer	computer	NOUN
fnp-3671	164	13	vision	vision	NOUN
fnp-3671	164	14	tool	tool	NOUN
fnp-3671	164	15	,	,	PUNCT
fnp-3671	164	16	scale	scale	NOUN
fnp-3671	164	17	-	-	PUNCT
fnp-3671	164	18	invariant	invariant	ADJ
fnp-3671	164	19	feature	feature	NOUN
fnp-3671	164	20	transform	transform	NOUN
fnp-3671	164	21	(	(	PUNCT
fnp-3671	164	22	sift	sift	NOUN
fnp-3671	164	23	)	)	PUNCT
fnp-3671	164	24	,	,	PUNCT
fnp-3671	164	25	to	to	PART
fnp-3671	164	26	align	align	VERB
fnp-3671	164	27	h&e	h&e	PROPN
fnp-3671	164	28	-	-	PUNCT
fnp-3671	164	29	stained	stain	VERB
fnp-3671	164	30	sections	section	NOUN
fnp-3671	164	31	with	with	ADP
fnp-3671	164	32	accompanying	accompany	VERB
fnp-3671	164	33	ihc	ihc	PROPN
fnp-3671	164	34	studies	study	NOUN
fnp-3671	164	35	for	for	ADP
fnp-3671	164	36	automated	automate	VERB
fnp-3671	164	37	subclassification	subclassification	NOUN
fnp-3671	164	38	of	of	ADP
fnp-3671	164	39	gliomas	glioma	NOUN
fnp-3671	164	40	.	.	PUNCT
fnp-3671	165	1	method	method	NOUN
fnp-3671	165	2	:	:	PUNCT
fnp-3671	165	3	to	to	PART
fnp-3671	165	4	test	test	VERB
fnp-3671	165	5	the	the	DET
fnp-3671	165	6	workflow	workflow	NOUN
fnp-3671	165	7	,	,	PUNCT
fnp-3671	165	8	we	we	PRON
fnp-3671	165	9	first	first	ADV
fnp-3671	165	10	trained	train	VERB
fnp-3671	165	11	a	a	DET
fnp-3671	165	12	vgg19	vgg19	NOUN
fnp-3671	165	13	convolutional	convolutional	ADJ
fnp-3671	165	14	neural	neural	ADJ
fnp-3671	165	15	network	network	NOUN
fnp-3671	165	16	(	(	PUNCT
fnp-3671	165	17	cnn	cnn	PROPN
fnp-3671	165	18	)	)	PUNCT
fnp-3671	165	19	using	use	VERB
fnp-3671	165	20	pathologist	pathologist	NOUN
fnp-3671	165	21	-	-	PUNCT
fnp-3671	165	22	annotated	annotate	VERB
fnp-3671	165	23	h&e	h&e	PROPN
fnp-3671	165	24	wsis	wsis	NOUN
fnp-3671	165	25	to	to	PART
fnp-3671	165	26	recognize	recognize	VERB
fnp-3671	165	27	histological	histological	ADJ
fnp-3671	165	28	patterns	pattern	NOUN
fnp-3671	165	29	of	of	ADP
fnp-3671	165	30	16	16	NUM
fnp-3671	165	31	common	common	ADJ
fnp-3671	165	32	tissue	tissue	NOUN
fnp-3671	165	33	and	and	CCONJ
fnp-3671	165	34	lesion	lesion	NOUN
fnp-3671	165	35	classes	class	NOUN
fnp-3671	165	36	.	.	PUNCT
fnp-3671	166	1	afterwards	afterwards	ADV
fnp-3671	166	2	,	,	PUNCT
fnp-3671	166	3	we	we	PRON
fnp-3671	166	4	optimized	optimize	VERB
fnp-3671	166	5	a	a	DET
fnp-3671	166	6	different	different	ADJ
fnp-3671	166	7	set	set	NOUN
fnp-3671	166	8	of	of	ADP
fnp-3671	166	9	cnns	cnn	NOUN
fnp-3671	166	10	to	to	PART
fnp-3671	166	11	recognize	recognize	VERB
fnp-3671	166	12	various	various	ADJ
fnp-3671	166	13	ihc	ihc	PROPN
fnp-3671	166	14	markers	marker	NOUN
fnp-3671	166	15	,	,	PUNCT
fnp-3671	166	16	such	such	ADJ
fnp-3671	166	17	as	as	ADP
fnp-3671	166	18	idh1	idh1	PROPN
fnp-3671	166	19	-	-	PUNCT
fnp-3671	166	20	r132h	r132h	PROPN
fnp-3671	166	21	and	and	CCONJ
fnp-3671	166	22	atrx	atrx	VERB
fnp-3671	166	23	,	,	PUNCT
fnp-3671	166	24	which	which	PRON
fnp-3671	166	25	are	be	AUX
fnp-3671	166	26	relevant	relevant	ADJ
fnp-3671	166	27	for	for	ADP
fnp-3671	166	28	molecular	molecular	ADJ
fnp-3671	166	29	subclassification	subclassification	NOUN
fnp-3671	166	30	of	of	ADP
fnp-3671	166	31	gliomas	glioma	NOUN
fnp-3671	166	32	.	.	PUNCT
fnp-3671	167	1	for	for	ADP
fnp-3671	167	2	the	the	DET
fnp-3671	167	3	integrated	integrate	VERB
fnp-3671	167	4	analysis	analysis	NOUN
fnp-3671	167	5	,	,	PUNCT
fnp-3671	167	6	we	we	PRON
fnp-3671	167	7	employed	employ	VERB
fnp-3671	167	8	sift	sift	VERB
fnp-3671	167	9	to	to	PART
fnp-3671	167	10	find	find	VERB
fnp-3671	167	11	features	feature	NOUN
fnp-3671	167	12	for	for	ADP
fnp-3671	167	13	image	image	NOUN
fnp-3671	167	14	matching	matching	NOUN
fnp-3671	167	15	which	which	PRON
fnp-3671	167	16	were	be	AUX
fnp-3671	167	17	used	use	VERB
fnp-3671	167	18	to	to	PART
fnp-3671	167	19	align	align	VERB
fnp-3671	167	20	lesional	lesional	ADJ
fnp-3671	167	21	regions	region	NOUN
fnp-3671	167	22	of	of	ADP
fnp-3671	167	23	h&e	h&e	PROPN
fnp-3671	167	24	and	and	CCONJ
fnp-3671	167	25	ihc	ihc	PROPN
fnp-3671	167	26	slides	slide	NOUN
fnp-3671	167	27	.	.	PUNCT
fnp-3671	168	1	results	result	NOUN
fnp-3671	168	2	:	:	PUNCT
fnp-3671	168	3	the	the	DET
fnp-3671	168	4	histomorphologic	histomorphologic	ADJ
fnp-3671	168	5	classifier	classifier	NOUN
fnp-3671	168	6	(	(	PUNCT
fnp-3671	168	7	cnnh&e	cnnh&e	PROPN
fnp-3671	168	8	)	)	PUNCT
fnp-3671	168	9	excelled	excel	VERB
fnp-3671	168	10	at	at	ADP
fnp-3671	168	11	classification	classification	NOUN
fnp-3671	168	12	with	with	ADP
fnp-3671	168	13	accuracies	accuracy	NOUN
fnp-3671	168	14	of	of	ADP
fnp-3671	168	15	100	100	NUM
fnp-3671	168	16	%	%	NOUN
fnp-3671	168	17	for	for	ADP
fnp-3671	168	18	glioma	glioma	NOUN
fnp-3671	168	19	,	,	PUNCT
fnp-3671	168	20	meningioma	meningioma	NOUN
fnp-3671	168	21	and	and	CCONJ
fnp-3671	168	22	metastatic	metastatic	ADJ
fnp-3671	168	23	carcinoma	carcinoma	NOUN
fnp-3671	168	24	,	,	PUNCT
fnp-3671	168	25	and	and	CCONJ
fnp-3671	168	26	93	93	NUM
fnp-3671	168	27	%	%	NOUN
fnp-3671	168	28	for	for	ADP
fnp-3671	168	29	schwannoma	schwannoma	NOUN
fnp-3671	168	30	(	(	PUNCT
fnp-3671	168	31	n	n	NOUN
fnp-3671	168	32	=	=	SYM
fnp-3671	168	33	125	125	NUM
fnp-3671	168	34	)	)	PUNCT
fnp-3671	168	35	.	.	PUNCT
fnp-3671	169	1	using	use	VERB
fnp-3671	169	2	the	the	DET
fnp-3671	169	3	newly	newly	ADV
fnp-3671	169	4	developed	develop	VERB
fnp-3671	169	5	cnnh&e	cnnh&e	PROPN
fnp-3671	169	6	and	and	CCONJ
fnp-3671	169	7	sift	sift	NOUN
fnp-3671	169	8	-	-	PUNCT
fnp-3671	169	9	based	base	VERB
fnp-3671	169	10	alignment	alignment	NOUN
fnp-3671	169	11	,	,	PUNCT
fnp-3671	169	12	the	the	DET
fnp-3671	169	13	quantitative	quantitative	ADJ
fnp-3671	169	14	analysis	analysis	NOUN
fnp-3671	169	15	by	by	ADP
fnp-3671	169	16	the	the	DET
fnp-3671	169	17	ihc	ihc	PROPN
fnp-3671	169	18	classifiers	classifier	NOUN
fnp-3671	169	19	significantly	significantly	ADV
fnp-3671	169	20	improved	improve	VERB
fnp-3671	169	21	for	for	ADP
fnp-3671	169	22	atrx	atrx	NOUN
fnp-3671	169	23	retained	retain	VERB
fnp-3671	169	24	and	and	CCONJ
fnp-3671	169	25	idh1	idh1	PROPN
fnp-3671	169	26	-	-	PUNCT
fnp-3671	169	27	r132h	r132h	PROPN
fnp-3671	169	28	positive	positive	ADJ
fnp-3671	169	29	wsis	wsis	NOUN
fnp-3671	169	30	when	when	SCONJ
fnp-3671	169	31	compared	compare	VERB
fnp-3671	169	32	to	to	ADP
fnp-3671	169	33	that	that	PRON
fnp-3671	169	34	of	of	ADP
fnp-3671	169	35	unaligned	unaligned	ADJ
fnp-3671	169	36	wsis	wsis	NOUN
fnp-3671	169	37	.	.	PUNCT
fnp-3671	170	1	conclusion	conclusion	NOUN
fnp-3671	170	2	:	:	PUNCT
fnp-3671	170	3	sift	sift	NOUN
fnp-3671	170	4	can	can	AUX
fnp-3671	170	5	work	work	VERB
fnp-3671	170	6	in	in	ADP
fnp-3671	170	7	concert	concert	NOUN
fnp-3671	170	8	with	with	ADP
fnp-3671	170	9	deep	deep	ADJ
fnp-3671	170	10	learning	learning	NOUN
fnp-3671	170	11	tools	tool	NOUN
fnp-3671	170	12	to	to	PART
fnp-3671	170	13	provide	provide	VERB
fnp-3671	170	14	a	a	DET
fnp-3671	170	15	pathologist	pathologist	NOUN
fnp-3671	170	16	-	-	PUNCT
fnp-3671	170	17	inspired	inspire	VERB
fnp-3671	170	18	workflow	workflow	NOUN
fnp-3671	170	19	to	to	PART
fnp-3671	170	20	help	help	VERB
fnp-3671	170	21	automate	automate	VERB
fnp-3671	170	22	advanced	advanced	ADJ
fnp-3671	170	23	immunohistochemically	immunohistochemically	ADV
fnp-3671	170	24	diagnostic	diagnostic	ADJ
fnp-3671	170	25	tasks	task	NOUN
fnp-3671	170	26	,	,	PUNCT
fnp-3671	170	27	such	such	ADJ
fnp-3671	170	28	as	as	ADP
fnp-3671	170	29	subclassification	subclassification	NOUN
fnp-3671	170	30	of	of	ADP
fnp-3671	170	31	glioma	glioma	NOUN
fnp-3671	170	32	.	.	PUNCT
fnp-3671	170	33	  	  	SPACE
fnp-3671	171	1	abstract	abstract	ADJ
fnp-3671	171	2	16	16	NUM
fnp-3671	171	3	free	free	ADJ
fnp-3671	171	4	neuropathol	neuropathol	NOUN
fnp-3671	171	5	2:29:19	2:29:19	NUM
fnp-3671	171	6	neuropathology	neuropathology	NOUN
fnp-3671	171	7	of	of	ADP
fnp-3671	171	8	eight	eight	NUM
fnp-3671	171	9	cases	case	NOUN
fnp-3671	171	10	of	of	ADP
fnp-3671	171	11	the	the	DET
fnp-3671	171	12	new	new	ADJ
fnp-3671	171	13	brunswick	brunswick	PROPN
fnp-3671	171	14	cluster	cluster	NOUN
fnp-3671	171	15	of	of	ADP
fnp-3671	171	16	neurological	neurological	ADJ
fnp-3671	171	17	syndrome	syndrome	NOUN
fnp-3671	171	18	of	of	ADP
fnp-3671	171	19	unknown	unknown	ADJ
fnp-3671	171	20	cause	cause	NOUN
fnp-3671	171	21	(	(	PUNCT
fnp-3671	171	22	nsuc	nsuc	ADJ
fnp-3671	171	23	)	)	PUNCT
fnp-3671	171	24	gerard	gerard	PROPN
fnp-3671	171	25	h.	h.	PROPN
fnp-3671	171	26	jansen1	jansen1	PROPN
fnp-3671	171	27	,	,	PUNCT
fnp-3671	171	28	sidney	sidney	PROPN
fnp-3671	171	29	e.	e.	PROPN
fnp-3671	171	30	croul2	croul2	PROPN
fnp-3671	171	31	,	,	PUNCT
fnp-3671	171	32	angela	angela	PROPN
fnp-3671	171	33	k.	k.	PROPN
fnp-3671	171	34	miller3	miller3	PROPN
fnp-3671	171	35	,	,	PUNCT
fnp-3671	171	36	alexander	alexander	PROPN
fnp-3671	171	37	s.	s.	PROPN
fnp-3671	171	38	easton2	easton2	PROPN
fnp-3671	171	39	,	,	PUNCT
fnp-3671	171	40	john	john	PROPN
fnp-3671	171	41	m.	m.	PROPN
fnp-3671	171	42	j.	j.	PROPN
fnp-3671	171	43	woulfe1	woulfe1	PROPN
fnp-3671	172	1	1	1	NUM
fnp-3671	172	2	department	department	NOUN
fnp-3671	172	3	of	of	ADP
fnp-3671	172	4	pathology	pathology	NOUN
fnp-3671	172	5	and	and	CCONJ
fnp-3671	172	6	laboratory	laboratory	NOUN
fnp-3671	172	7	medicine	medicine	NOUN
fnp-3671	172	8	,	,	PUNCT
fnp-3671	172	9	university	university	PROPN
fnp-3671	172	10	of	of	ADP
fnp-3671	172	11	ottawa	ottawa	PROPN
fnp-3671	172	12	,	,	PUNCT
fnp-3671	172	13	ottawa	ottawa	PROPN
fnp-3671	172	14	,	,	PUNCT
fnp-3671	172	15	ontario	ontario	PROPN
fnp-3671	172	16	,	,	PUNCT
fnp-3671	172	17	canada	canada	PROPN
fnp-3671	172	18	2	2	NUM
fnp-3671	172	19	department	department	NOUN
fnp-3671	172	20	of	of	ADP
fnp-3671	172	21	pathology	pathology	PROPN
fnp-3671	172	22	,	,	PUNCT
fnp-3671	172	23	qeii	qeii	VERB
fnp-3671	172	24	health	health	NOUN
fnp-3671	172	25	science	science	NOUN
fnp-3671	172	26	centre	centre	PROPN
fnp-3671	172	27	,	,	PUNCT
fnp-3671	172	28	halifax	halifax	PROPN
fnp-3671	172	29	,	,	PUNCT
fnp-3671	172	30	nova	nova	PROPN
fnp-3671	172	31	scotia	scotia	PROPN
fnp-3671	172	32	,	,	PUNCT
fnp-3671	172	33	canada	canada	PROPN
fnp-3671	172	34	3	3	NUM
fnp-3671	172	35	department	department	PROPN
fnp-3671	172	36	of	of	ADP
fnp-3671	172	37	pathology	pathology	PROPN
fnp-3671	172	38	,	,	PUNCT
fnp-3671	172	39	health	health	PROPN
fnp-3671	172	40	sciences	sciences	PROPN
fnp-3671	172	41	centre	centre	PROPN
fnp-3671	172	42	,	,	PUNCT
fnp-3671	172	43	winnipeg	winnipeg	PROPN
fnp-3671	172	44	,	,	PUNCT
fnp-3671	172	45	manitoba	manitoba	PROPN
fnp-3671	172	46	,	,	PUNCT
fnp-3671	172	47	canada	canada	PROPN
fnp-3671	172	48	(	(	PUNCT
fnp-3671	172	49	previously	previously	ADV
fnp-3671	172	50	department	department	NOUN
fnp-3671	172	51	of	of	ADP
fnp-3671	172	52	pathology	pathology	PROPN
fnp-3671	172	53	,	,	PUNCT
fnp-3671	172	54	moncton	moncton	PROPN
fnp-3671	172	55	hospital	hospital	PROPN
fnp-3671	172	56	,	,	PUNCT
fnp-3671	172	57	moncton	moncton	PROPN
fnp-3671	172	58	,	,	PUNCT
fnp-3671	172	59	new	new	PROPN
fnp-3671	172	60	brunswick	brunswick	PROPN
fnp-3671	172	61	,	,	PUNCT
fnp-3671	172	62	canada	canada	PROPN
fnp-3671	172	63	)	)	PUNCT
fnp-3671	172	64	on	on	ADP
fnp-3671	172	65	march	march	PROPN
fnp-3671	172	66	17	17	NUM
fnp-3671	172	67	,	,	PUNCT
fnp-3671	172	68	2021	2021	NUM
fnp-3671	172	69	a	a	DET
fnp-3671	172	70	press	press	NOUN
fnp-3671	172	71	conference	conference	NOUN
fnp-3671	172	72	aired	air	VERB
fnp-3671	172	73	featuring	feature	VERB
fnp-3671	172	74	a	a	DET
fnp-3671	172	75	moncton	moncton	NOUN
fnp-3671	172	76	neurologist	neurologist	NOUN
fnp-3671	172	77	and	and	CCONJ
fnp-3671	172	78	new	new	PROPN
fnp-3671	172	79	brunswick	brunswick	PROPN
fnp-3671	172	80	’s	’s	PART
fnp-3671	172	81	chief	chief	ADJ
fnp-3671	172	82	medical	medical	ADJ
fnp-3671	172	83	health	health	NOUN
fnp-3671	172	84	officer	officer	NOUN
fnp-3671	172	85	,	,	PUNCT
fnp-3671	172	86	regarding	regard	VERB
fnp-3671	172	87	a	a	DET
fnp-3671	172	88	cluster	cluster	NOUN
fnp-3671	172	89	of	of	ADP
fnp-3671	172	90	patients	patient	NOUN
fnp-3671	172	91	in	in	ADP
fnp-3671	172	92	new	new	PROPN
fnp-3671	172	93	brunswick	brunswick	PROPN
fnp-3671	172	94	who	who	PRON
fnp-3671	172	95	had	have	VERB
fnp-3671	172	96	symptoms	symptom	NOUN
fnp-3671	172	97	reminiscent	reminiscent	ADJ
fnp-3671	172	98	of	of	ADP
fnp-3671	172	99	cjd	cjd	PROPN
fnp-3671	172	100	,	,	PUNCT
fnp-3671	172	101	and	and	CCONJ
fnp-3671	172	102	were	be	AUX
fnp-3671	172	103	claimed	claim	VERB
fnp-3671	172	104	to	to	PART
fnp-3671	172	105	have	have	VERB
fnp-3671	172	106	a	a	DET
fnp-3671	172	107	novel	novel	ADJ
fnp-3671	172	108	neurological	neurological	ADJ
fnp-3671	172	109	syndrome	syndrome	NOUN
fnp-3671	172	110	.	.	PUNCT
fnp-3671	173	1	the	the	DET
fnp-3671	173	2	onset	onset	NOUN
fnp-3671	173	3	of	of	ADP
fnp-3671	173	4	the	the	DET
fnp-3671	173	5	disease	disease	NOUN
fnp-3671	173	6	was	be	AUX
fnp-3671	173	7	between	between	ADP
fnp-3671	173	8	2015	2015	NUM
fnp-3671	173	9	and	and	CCONJ
fnp-3671	173	10	2021	2021	NUM
fnp-3671	173	11	.	.	PUNCT
fnp-3671	174	1	all	all	DET
fnp-3671	174	2	patients	patient	NOUN
fnp-3671	174	3	in	in	ADP
fnp-3671	174	4	that	that	DET
fnp-3671	174	5	cluster	cluster	NOUN
fnp-3671	174	6	had	have	AUX
fnp-3671	174	7	at	at	ADP
fnp-3671	174	8	that	that	DET
fnp-3671	174	9	time	time	NOUN
fnp-3671	174	10	been	be	AUX
fnp-3671	174	11	reported	report	VERB
fnp-3671	174	12	by	by	ADP
fnp-3671	174	13	one	one	NUM
fnp-3671	174	14	neurologist	neurologist	NOUN
fnp-3671	174	15	,	,	PUNCT
fnp-3671	174	16	although	although	SCONJ
fnp-3671	174	17	subsequently	subsequently	ADV
fnp-3671	174	18	a	a	DET
fnp-3671	174	19	few	few	ADJ
fnp-3671	174	20	incidental	incidental	ADJ
fnp-3671	174	21	cases	case	NOUN
fnp-3671	174	22	were	be	AUX
fnp-3671	174	23	reported	report	VERB
fnp-3671	174	24	by	by	ADP
fnp-3671	174	25	other	other	ADJ
fnp-3671	174	26	neurologists	neurologist	NOUN
fnp-3671	174	27	.	.	PUNCT
fnp-3671	175	1	the	the	DET
fnp-3671	175	2	size	size	NOUN
fnp-3671	175	3	of	of	ADP
fnp-3671	175	4	this	this	DET
fnp-3671	175	5	cluster	cluster	NOUN
fnp-3671	175	6	has	have	AUX
fnp-3671	175	7	been	be	AUX
fnp-3671	175	8	reported	report	VERB
fnp-3671	175	9	at	at	ADP
fnp-3671	175	10	around	around	ADV
fnp-3671	175	11	50	50	NUM
fnp-3671	175	12	cases	case	NOUN
fnp-3671	175	13	.	.	PUNCT
fnp-3671	176	1	further	further	ADJ
fnp-3671	176	2	news	news	NOUN
fnp-3671	176	3	publications	publication	NOUN
fnp-3671	176	4	have	have	AUX
fnp-3671	176	5	suggested	suggest	VERB
fnp-3671	176	6	that	that	SCONJ
fnp-3671	176	7	an	an	DET
fnp-3671	176	8	environmental	environmental	ADJ
fnp-3671	176	9	factor	factor	NOUN
fnp-3671	176	10	is	be	AUX
fnp-3671	176	11	the	the	DET
fnp-3671	176	12	causative	causative	ADJ
fnp-3671	176	13	factor	factor	NOUN
fnp-3671	176	14	for	for	ADP
fnp-3671	176	15	this	this	DET
fnp-3671	176	16	cluster	cluster	NOUN
fnp-3671	176	17	.	.	PUNCT
fnp-3671	177	1	this	this	DET
fnp-3671	177	2	news	news	NOUN
fnp-3671	177	3	has	have	AUX
fnp-3671	177	4	significantly	significantly	ADV
fnp-3671	177	5	disturbed	disturb	VERB
fnp-3671	177	6	the	the	DET
fnp-3671	177	7	medical	medical	ADJ
fnp-3671	177	8	community	community	NOUN
fnp-3671	177	9	.	.	PUNCT
fnp-3671	178	1	since	since	SCONJ
fnp-3671	178	2	2019	2019	NUM
fnp-3671	178	3	eight	eight	NUM
fnp-3671	178	4	patients	patient	NOUN
fnp-3671	178	5	have	have	AUX
fnp-3671	178	6	died	die	VERB
fnp-3671	178	7	that	that	PRON
fnp-3671	178	8	belonged	belong	VERB
fnp-3671	178	9	to	to	ADP
fnp-3671	178	10	this	this	DET
fnp-3671	178	11	cluster	cluster	NOUN
fnp-3671	178	12	.	.	PUNCT
fnp-3671	179	1	we	we	PRON
fnp-3671	179	2	report	report	VERB
fnp-3671	179	3	their	their	PRON
fnp-3671	179	4	neuropathological	neuropathological	ADJ
fnp-3671	179	5	findings	finding	NOUN
fnp-3671	179	6	and	and	CCONJ
fnp-3671	179	7	hope	hope	VERB
fnp-3671	179	8	this	this	PRON
fnp-3671	179	9	will	will	AUX
fnp-3671	179	10	bring	bring	VERB
fnp-3671	179	11	some	some	DET
fnp-3671	179	12	clarity	clarity	NOUN
fnp-3671	179	13	.	.	PUNCT
fnp-3671	180	1	there	there	PRON
fnp-3671	180	2	was	be	VERB
fnp-3671	180	3	one	one	NUM
fnp-3671	180	4	case	case	NOUN
fnp-3671	180	5	of	of	ADP
fnp-3671	180	6	metastatic	metastatic	ADJ
fnp-3671	180	7	carcinoma	carcinoma	NOUN
fnp-3671	180	8	,	,	PUNCT
fnp-3671	180	9	one	one	NUM
fnp-3671	180	10	case	case	NOUN
fnp-3671	180	11	of	of	ADP
fnp-3671	180	12	ftld	ftld	NOUN
fnp-3671	180	13	-	-	PUNCT
fnp-3671	180	14	tdp43	tdp43	NOUN
fnp-3671	180	15	,	,	PUNCT
fnp-3671	180	16	one	one	NUM
fnp-3671	180	17	case	case	NOUN
fnp-3671	180	18	of	of	ADP
fnp-3671	180	19	neocortical	neocortical	ADJ
fnp-3671	180	20	lewy	lewy	ADJ
fnp-3671	180	21	body	body	NOUN
fnp-3671	180	22	pathology	pathology	NOUN
fnp-3671	180	23	,	,	PUNCT
fnp-3671	180	24	one	one	NUM
fnp-3671	180	25	case	case	NOUN
fnp-3671	180	26	of	of	ADP
fnp-3671	180	27	neocortical	neocortical	ADJ
fnp-3671	180	28	lewy	lewy	ADJ
fnp-3671	180	29	body	body	NOUN
fnp-3671	180	30	pathology	pathology	NOUN
fnp-3671	180	31	and	and	CCONJ
fnp-3671	180	32	ad	ad	NOUN
fnp-3671	180	33	,	,	PUNCT
fnp-3671	180	34	2	2	NUM
fnp-3671	180	35	cases	case	NOUN
fnp-3671	180	36	of	of	ADP
fnp-3671	180	37	ad	ad	NOUN
fnp-3671	180	38	with	with	ADP
fnp-3671	180	39	vascular	vascular	ADJ
fnp-3671	180	40	pathology	pathology	NOUN
fnp-3671	180	41	,	,	PUNCT
fnp-3671	180	42	one	one	NUM
fnp-3671	180	43	case	case	NOUN
fnp-3671	180	44	of	of	ADP
fnp-3671	180	45	mainly	mainly	ADV
fnp-3671	180	46	vascular	vascular	ADJ
fnp-3671	180	47	pathology	pathology	NOUN
fnp-3671	180	48	,	,	PUNCT
fnp-3671	180	49	and	and	CCONJ
fnp-3671	180	50	one	one	NUM
fnp-3671	180	51	case	case	NOUN
fnp-3671	180	52	without	without	ADP
fnp-3671	180	53	significant	significant	ADJ
fnp-3671	180	54	pathology	pathology	NOUN
fnp-3671	180	55	(	(	PUNCT
fnp-3671	180	56	consistent	consistent	ADJ
fnp-3671	180	57	with	with	ADP
fnp-3671	180	58	the	the	DET
fnp-3671	180	59	patient	patient	NOUN
fnp-3671	180	60	’s	’s	PART
fnp-3671	180	61	previous	previous	ADJ
fnp-3671	180	62	history	history	NOUN
fnp-3671	180	63	)	)	PUNCT
fnp-3671	180	64	.	.	PUNCT
fnp-3671	181	1	in	in	ADP
fnp-3671	181	2	these	these	DET
fnp-3671	181	3	8	8	NUM
fnp-3671	181	4	patients	patient	NOUN
fnp-3671	181	5	no	no	DET
fnp-3671	181	6	evidence	evidence	NOUN
fnp-3671	181	7	for	for	ADP
fnp-3671	181	8	a	a	DET
fnp-3671	181	9	prion	prion	NOUN
fnp-3671	181	10	disease	disease	NOUN
fnp-3671	181	11	was	be	AUX
fnp-3671	181	12	found	find	VERB
fnp-3671	181	13	,	,	PUNCT
fnp-3671	181	14	nor	nor	CCONJ
fnp-3671	181	15	novel	novel	ADJ
fnp-3671	181	16	pathology	pathology	NOUN
fnp-3671	181	17	.	.	PUNCT
fnp-3671	182	1	we	we	PRON
fnp-3671	182	2	suggest	suggest	VERB
fnp-3671	182	3	that	that	SCONJ
fnp-3671	182	4	these	these	DET
fnp-3671	182	5	8	8	NUM
fnp-3671	182	6	patients	patient	NOUN
fnp-3671	182	7	represent	represent	VERB
fnp-3671	182	8	a	a	DET
fnp-3671	182	9	group	group	NOUN
fnp-3671	182	10	of	of	ADP
fnp-3671	182	11	misclassified	misclassifie	VERB
fnp-3671	182	12	clinical	clinical	ADJ
fnp-3671	182	13	diagnoses	diagnosis	NOUN
fnp-3671	182	14	.	.	PUNCT
fnp-3671	183	1	since	since	SCONJ
fnp-3671	183	2	june	june	PROPN
fnp-3671	183	3	3	3	NUM
fnp-3671	183	4	,	,	PUNCT
fnp-3671	183	5	2021	2021	NUM
fnp-3671	183	6	the	the	DET
fnp-3671	183	7	oversight	oversight	NOUN
fnp-3671	183	8	committee	committee	NOUN
fnp-3671	183	9	was	be	AUX
fnp-3671	183	10	established	establish	VERB
fnp-3671	183	11	in	in	ADP
fnp-3671	183	12	new	new	PROPN
fnp-3671	183	13	brunswick	brunswick	PROPN
fnp-3671	183	14	reviewing	review	VERB
fnp-3671	183	15	the	the	DET
fnp-3671	183	16	clinical	clinical	ADJ
fnp-3671	183	17	and	and	CCONJ
fnp-3671	183	18	epidemiological	epidemiological	ADJ
fnp-3671	183	19	data	datum	NOUN
fnp-3671	183	20	of	of	ADP
fnp-3671	183	21	the	the	DET
fnp-3671	183	22	patients	patient	NOUN
fnp-3671	183	23	in	in	ADP
fnp-3671	183	24	this	this	DET
fnp-3671	183	25	cluster	cluster	NOUN
fnp-3671	183	26	.	.	PUNCT
fnp-3671	184	1	we	we	PRON
fnp-3671	184	2	hope	hope	VERB
fnp-3671	184	3	that	that	SCONJ
fnp-3671	184	4	our	our	PRON
fnp-3671	184	5	findings	finding	NOUN
fnp-3671	184	6	are	be	AUX
fnp-3671	184	7	useful	useful	ADJ
fnp-3671	184	8	to	to	ADP
fnp-3671	184	9	them	they	PRON
fnp-3671	184	10	.	.	PUNCT
fnp-3671	184	11	  	  	SPACE
fnp-3671	185	1	abstract	abstract	ADJ
fnp-3671	185	2	17	17	NUM
fnp-3671	185	3	free	free	ADJ
fnp-3671	185	4	neuropathol	neuropathol	NOUN
fnp-3671	185	5	2:29:20	2:29:20	NUM
fnp-3671	185	6	covid-19	covid-19	PROPN
fnp-3671	185	7	pandemic	pandemic	ADJ
fnp-3671	185	8	impact	impact	NOUN
fnp-3671	185	9	on	on	ADP
fnp-3671	185	10	surgical	surgical	ADJ
fnp-3671	185	11	neuropathology	neuropathology	NOUN
fnp-3671	185	12	services	service	NOUN
fnp-3671	185	13	at	at	ADP
fnp-3671	185	14	london	london	PROPN
fnp-3671	185	15	health	health	PROPN
fnp-3671	185	16	sciences	sciences	PROPN
fnp-3671	185	17	centre	centre	PROPN
fnp-3671	185	18	shervin	shervin	PROPN
fnp-3671	185	19	pejhan1	pejhan1	PROPN
fnp-3671	185	20	,	,	PUNCT
fnp-3671	185	21	chris	chris	PROPN
fnp-3671	185	22	tran1	tran1	PROPN
fnp-3671	185	23	,	,	PUNCT
fnp-3671	185	24	david	david	PROPN
fnp-3671	185	25	driman1	driman1	PROPN
fnp-3671	185	26	,	,	PUNCT
fnp-3671	185	27	robert	robert	PROPN
fnp-3671	185	28	hammond1,2	hammond1,2	PROPN
fnp-3671	185	29	,	,	PUNCT
fnp-3671	185	30	lee	lee	PROPN
fnp-3671	185	31	cyn	cyn	PROPN
fnp-3671	185	32	ang1,2	ang1,2	PROPN
fnp-3671	185	33	,	,	PUNCT
fnp-3671	185	34	qi	qi	PROPN
fnp-3671	185	35	zhang1,2	zhang1,2	PROPN
fnp-3671	185	36	1	1	NUM
fnp-3671	185	37	department	department	NOUN
fnp-3671	185	38	of	of	ADP
fnp-3671	185	39	pathology	pathology	PROPN
fnp-3671	185	40	&	&	CCONJ
fnp-3671	185	41	lab	lab	PROPN
fnp-3671	185	42	medicine	medicine	NOUN
fnp-3671	185	43	,	,	PUNCT
fnp-3671	185	44	london	london	PROPN
fnp-3671	185	45	health	health	PROPN
fnp-3671	185	46	sciences	sciences	PROPN
fnp-3671	185	47	centre	centre	PROPN
fnp-3671	185	48	,	,	PUNCT
fnp-3671	185	49	london	london	PROPN
fnp-3671	185	50	,	,	PUNCT
fnp-3671	185	51	ontario	ontario	PROPN
fnp-3671	185	52	,	,	PUNCT
fnp-3671	185	53	canada	canada	PROPN
fnp-3671	185	54	2	2	NUM
fnp-3671	185	55	department	department	NOUN
fnp-3671	185	56	of	of	ADP
fnp-3671	185	57	clinical	clinical	ADJ
fnp-3671	185	58	neurological	neurological	ADJ
fnp-3671	185	59	sciences	science	NOUN
fnp-3671	185	60	,	,	PUNCT
fnp-3671	185	61	london	london	PROPN
fnp-3671	185	62	health	health	PROPN
fnp-3671	185	63	sciences	sciences	PROPN
fnp-3671	185	64	centre	centre	PROPN
fnp-3671	185	65	,	,	PUNCT
fnp-3671	185	66	london	london	PROPN
fnp-3671	185	67	,	,	PUNCT
fnp-3671	185	68	ontario	ontario	PROPN
fnp-3671	185	69	,	,	PUNCT
fnp-3671	185	70	canada	canada	PROPN
fnp-3671	185	71	the	the	DET
fnp-3671	185	72	covid-19	covid-19	PROPN
fnp-3671	185	73	pandemic	pandemic	NOUN
fnp-3671	185	74	has	have	AUX
fnp-3671	185	75	had	have	VERB
fnp-3671	185	76	a	a	DET
fnp-3671	185	77	significant	significant	ADJ
fnp-3671	185	78	impact	impact	NOUN
fnp-3671	185	79	on	on	ADP
fnp-3671	185	80	medical	medical	ADJ
fnp-3671	185	81	services	service	NOUN
fnp-3671	185	82	.	.	PUNCT
fnp-3671	186	1	many	many	ADJ
fnp-3671	186	2	jurisdictions	jurisdiction	NOUN
fnp-3671	186	3	postponed	postpone	VERB
fnp-3671	186	4	non	non	ADJ
fnp-3671	186	5	-	-	ADJ
fnp-3671	186	6	urgent	urgent	ADJ
fnp-3671	186	7	procedures	procedure	NOUN
fnp-3671	186	8	to	to	PART
fnp-3671	186	9	balance	balance	VERB
fnp-3671	186	10	individual	individual	ADJ
fnp-3671	186	11	patient	patient	NOUN
fnp-3671	186	12	care	care	NOUN
fnp-3671	186	13	with	with	ADP
fnp-3671	186	14	public	public	ADJ
fnp-3671	186	15	health	health	NOUN
fnp-3671	186	16	precautions	precaution	NOUN
fnp-3671	186	17	.	.	PUNCT
fnp-3671	187	1	surgical	surgical	ADJ
fnp-3671	187	2	backlogs	backlog	NOUN
fnp-3671	187	3	caused	cause	VERB
fnp-3671	187	4	by	by	ADP
fnp-3671	187	5	the	the	DET
fnp-3671	187	6	covid-19	covid-19	PROPN
fnp-3671	187	7	pandemic	pandemic	NOUN
fnp-3671	187	8	have	have	AUX
fnp-3671	187	9	been	be	AUX
fnp-3671	187	10	evaluated	evaluate	VERB
fnp-3671	187	11	by	by	ADP
fnp-3671	187	12	different	different	ADJ
fnp-3671	187	13	groups	group	NOUN
fnp-3671	187	14	.	.	PUNCT
fnp-3671	188	1	however	however	ADV
fnp-3671	188	2	,	,	PUNCT
fnp-3671	188	3	the	the	DET
fnp-3671	188	4	impact	impact	NOUN
fnp-3671	188	5	of	of	ADP
fnp-3671	188	6	this	this	DET
fnp-3671	188	7	pandemic	pandemic	NOUN
fnp-3671	188	8	on	on	ADP
fnp-3671	188	9	pathology	pathology	NOUN
fnp-3671	188	10	and	and	CCONJ
fnp-3671	188	11	specifically	specifically	ADV
fnp-3671	188	12	neuropathology	neuropathology	NOUN
fnp-3671	188	13	(	(	PUNCT
fnp-3671	188	14	np	np	INTJ
fnp-3671	188	15	)	)	PUNCT
fnp-3671	188	16	services	service	NOUN
fnp-3671	188	17	has	have	AUX
fnp-3671	188	18	received	receive	VERB
fnp-3671	188	19	limited	limited	ADJ
fnp-3671	188	20	attention	attention	NOUN
fnp-3671	188	21	.	.	PUNCT
fnp-3671	189	1	in	in	ADP
fnp-3671	189	2	this	this	DET
fnp-3671	189	3	study	study	NOUN
fnp-3671	189	4	,	,	PUNCT
fnp-3671	189	5	we	we	PRON
fnp-3671	189	6	reviewed	review	VERB
fnp-3671	189	7	all	all	PRON
fnp-3671	189	8	surgical	surgical	ADJ
fnp-3671	189	9	np	np	ADP
fnp-3671	189	10	reports	report	NOUN
fnp-3671	189	11	of	of	ADP
fnp-3671	189	12	our	our	PRON
fnp-3671	189	13	centre	centre	NOUN
fnp-3671	189	14	from	from	ADP
fnp-3671	189	15	march	march	PROPN
fnp-3671	189	16	2018	2018	NUM
fnp-3671	189	17	(	(	PUNCT
fnp-3671	189	18	two	two	NUM
fnp-3671	189	19	years	year	NOUN
fnp-3671	189	20	before	before	ADP
fnp-3671	189	21	the	the	DET
fnp-3671	189	22	pandemic	pandemic	ADJ
fnp-3671	189	23	declaration	declaration	NOUN
fnp-3671	189	24	)	)	PUNCT
fnp-3671	189	25	through	through	ADP
fnp-3671	189	26	july	july	PROPN
fnp-3671	189	27	2021	2021	NUM
fnp-3671	189	28	.	.	PUNCT
fnp-3671	190	1	patient	patient	ADJ
fnp-3671	190	2	demographic	demographic	ADJ
fnp-3671	190	3	information	information	NOUN
fnp-3671	190	4	and	and	CCONJ
fnp-3671	190	5	pathological	pathological	ADJ
fnp-3671	190	6	variables	variable	NOUN
fnp-3671	190	7	were	be	AUX
fnp-3671	190	8	collected	collect	VERB
fnp-3671	190	9	.	.	PUNCT
fnp-3671	191	1	for	for	ADP
fnp-3671	191	2	tumours	tumour	NOUN
fnp-3671	191	3	,	,	PUNCT
fnp-3671	191	4	site	site	NOUN
fnp-3671	191	5	,	,	PUNCT
fnp-3671	191	6	type	type	NOUN
fnp-3671	191	7	,	,	PUNCT
fnp-3671	191	8	and	and	CCONJ
fnp-3671	191	9	who	who	PRON
fnp-3671	191	10	grade	grade	NOUN
fnp-3671	191	11	were	be	AUX
fnp-3671	191	12	analyzed	analyze	VERB
fnp-3671	191	13	.	.	PUNCT
fnp-3671	192	1	within	within	ADP
fnp-3671	192	2	the	the	DET
fnp-3671	192	3	period	period	NOUN
fnp-3671	192	4	under	under	ADP
fnp-3671	192	5	study	study	NOUN
fnp-3671	192	6	,	,	PUNCT
fnp-3671	192	7	the	the	DET
fnp-3671	192	8	total	total	ADJ
fnp-3671	192	9	number	number	NOUN
fnp-3671	192	10	of	of	ADP
fnp-3671	192	11	np	np	PRON
fnp-3671	192	12	samples	sample	NOUN
fnp-3671	192	13	was	be	AUX
fnp-3671	192	14	lowest	low	ADJ
fnp-3671	192	15	in	in	ADP
fnp-3671	192	16	april	april	PROPN
fnp-3671	192	17	2020	2020	NUM
fnp-3671	192	18	,	,	PUNCT
fnp-3671	192	19	corresponding	correspond	VERB
fnp-3671	192	20	to	to	ADP
fnp-3671	192	21	the	the	DET
fnp-3671	192	22	first	first	ADJ
fnp-3671	192	23	ontario	ontario	PROPN
fnp-3671	192	24	provincial	provincial	ADJ
fnp-3671	192	25	lockdown	lockdown	NOUN
fnp-3671	192	26	.	.	PUNCT
fnp-3671	193	1	in	in	ADP
fnp-3671	193	2	comparison	comparison	NOUN
fnp-3671	193	3	to	to	ADP
fnp-3671	193	4	the	the	DET
fnp-3671	193	5	dramatic	dramatic	ADJ
fnp-3671	193	6	decrease	decrease	NOUN
fnp-3671	193	7	in	in	ADP
fnp-3671	193	8	other	other	ADJ
fnp-3671	193	9	surgical	surgical	ADJ
fnp-3671	193	10	pathology	pathology	NOUN
fnp-3671	193	11	subspecialties	subspecialtie	NOUN
fnp-3671	193	12	(	(	PUNCT
fnp-3671	193	13	camj	camj	NOUN
fnp-3671	193	14	2021;193(10	2021;193(10	PROPN
fnp-3671	193	15	):	):	PUNCT
fnp-3671	193	16	e343	e343	PROPN
fnp-3671	193	17	)	)	PUNCT
fnp-3671	193	18	,	,	PUNCT
fnp-3671	193	19	the	the	DET
fnp-3671	193	20	np	np	INTJ
fnp-3671	193	21	surgical	surgical	ADJ
fnp-3671	193	22	specimen	speciman	NOUN
fnp-3671	193	23	initially	initially	ADV
fnp-3671	193	24	had	have	VERB
fnp-3671	193	25	a	a	DET
fnp-3671	193	26	minimal	minimal	ADJ
fnp-3671	193	27	volume	volume	NOUN
fnp-3671	193	28	reduction	reduction	NOUN
fnp-3671	193	29	,	,	PUNCT
fnp-3671	193	30	with	with	ADP
fnp-3671	193	31	a	a	DET
fnp-3671	193	32	rapid	rapid	ADJ
fnp-3671	193	33	return	return	NOUN
fnp-3671	193	34	to	to	AUX
fnp-3671	193	35	baseline	baseline	VERB
fnp-3671	193	36	.	.	PUNCT
fnp-3671	194	1	among	among	ADP
fnp-3671	194	2	the	the	DET
fnp-3671	194	3	different	different	ADJ
fnp-3671	194	4	types	type	NOUN
fnp-3671	194	5	of	of	ADP
fnp-3671	194	6	np	np	PRON
fnp-3671	194	7	surgical	surgical	ADJ
fnp-3671	194	8	specimens	specimen	NOUN
fnp-3671	194	9	,	,	PUNCT
fnp-3671	194	10	muscle	muscle	NOUN
fnp-3671	194	11	biopsy	biopsy	NOUN
fnp-3671	194	12	and	and	CCONJ
fnp-3671	194	13	epilepsy	epilepsy	NOUN
fnp-3671	194	14	-	-	PUNCT
fnp-3671	194	15	related	relate	VERB
fnp-3671	194	16	specimens	specimen	NOUN
fnp-3671	194	17	showed	show	VERB
fnp-3671	194	18	a	a	DET
fnp-3671	194	19	more	more	ADV
fnp-3671	194	20	significant	significant	ADJ
fnp-3671	194	21	reduction	reduction	NOUN
fnp-3671	194	22	.	.	PUNCT
fnp-3671	195	1	there	there	PRON
fnp-3671	195	2	was	be	VERB
fnp-3671	195	3	a	a	DET
fnp-3671	195	4	slight	slight	ADJ
fnp-3671	195	5	increase	increase	NOUN
fnp-3671	195	6	in	in	ADP
fnp-3671	195	7	higher	high	ADJ
fnp-3671	195	8	-	-	PUNCT
fnp-3671	195	9	grade	grade	NOUN
fnp-3671	195	10	tumours	tumour	NOUN
fnp-3671	195	11	.	.	PUNCT
fnp-3671	196	1	interestingly	interestingly	ADV
fnp-3671	196	2	,	,	PUNCT
fnp-3671	196	3	a	a	DET
fnp-3671	196	4	gradual	gradual	ADJ
fnp-3671	196	5	increase	increase	NOUN
fnp-3671	196	6	of	of	ADP
fnp-3671	196	7	brain	brain	NOUN
fnp-3671	196	8	biopsies	biopsy	NOUN
fnp-3671	196	9	for	for	ADP
fnp-3671	196	10	inflammatory	inflammatory	ADJ
fnp-3671	196	11	conditions	condition	NOUN
fnp-3671	196	12	was	be	AUX
fnp-3671	196	13	noticed	notice	VERB
fnp-3671	196	14	.	.	PUNCT
fnp-3671	197	1	our	our	PRON
fnp-3671	197	2	results	result	NOUN
fnp-3671	197	3	show	show	VERB
fnp-3671	197	4	that	that	SCONJ
fnp-3671	197	5	the	the	DET
fnp-3671	197	6	neuropathology	neuropathology	NOUN
fnp-3671	197	7	service	service	NOUN
fnp-3671	197	8	volume	volume	NOUN
fnp-3671	197	9	reduction	reduction	NOUN
fnp-3671	197	10	due	due	ADP
fnp-3671	197	11	to	to	ADP
fnp-3671	197	12	the	the	DET
fnp-3671	197	13	covid-19	covid-19	PROPN
fnp-3671	197	14	pandemic	pandemic	NOUN
fnp-3671	197	15	has	have	AUX
fnp-3671	197	16	not	not	PART
fnp-3671	197	17	been	be	AUX
fnp-3671	197	18	as	as	ADV
fnp-3671	197	19	significant	significant	ADJ
fnp-3671	197	20	as	as	ADP
fnp-3671	197	21	other	other	ADJ
fnp-3671	197	22	pathology	pathology	NOUN
fnp-3671	197	23	subspecialties	subspecialtie	NOUN
fnp-3671	197	24	.	.	PUNCT
fnp-3671	198	1	studying	study	VERB
fnp-3671	198	2	the	the	DET
fnp-3671	198	3	variations	variation	NOUN
fnp-3671	198	4	in	in	ADP
fnp-3671	198	5	histopathological	histopathological	ADJ
fnp-3671	198	6	diagnoses	diagnosis	NOUN
fnp-3671	198	7	in	in	ADP
fnp-3671	198	8	pandemic	pandemic	ADJ
fnp-3671	198	9	years	year	NOUN
fnp-3671	198	10	could	could	AUX
fnp-3671	198	11	be	be	AUX
fnp-3671	198	12	helpful	helpful	ADJ
fnp-3671	198	13	for	for	ADP
fnp-3671	198	14	future	future	ADJ
fnp-3671	198	15	planning	planning	NOUN
fnp-3671	198	16	in	in	ADP
fnp-3671	198	17	both	both	CCONJ
fnp-3671	198	18	clinical	clinical	ADJ
fnp-3671	198	19	and	and	CCONJ
fnp-3671	198	20	pathological	pathological	ADJ
fnp-3671	198	21	sectors	sector	NOUN
fnp-3671	198	22	,	,	PUNCT
fnp-3671	198	23	especially	especially	ADV
fnp-3671	198	24	when	when	SCONJ
fnp-3671	198	25	the	the	DET
fnp-3671	198	26	data	datum	NOUN
fnp-3671	198	27	is	be	AUX
fnp-3671	198	28	strengthened	strengthen	VERB
fnp-3671	198	29	by	by	ADP
fnp-3671	198	30	the	the	DET
fnp-3671	198	31	experiences	experience	NOUN
fnp-3671	198	32	of	of	ADP
fnp-3671	198	33	other	other	ADJ
fnp-3671	198	34	medical	medical	ADJ
fnp-3671	198	35	centers	center	NOUN
fnp-3671	198	36	.	.	PUNCT
fnp-3671	198	37	  	  	SPACE
fnp-3671	199	1	copyright	copyright	NOUN
fnp-3671	199	2	:	:	PUNCT
fnp-3671	199	3	©	©	PROPN
fnp-3671	199	4	2021	2021	NUM
fnp-3671	199	5	the	the	DET
fnp-3671	199	6	author(s	author(s	NOUN
fnp-3671	199	7	)	)	PUNCT
fnp-3671	199	8	.	.	PUNCT
fnp-3671	200	1	this	this	PRON
fnp-3671	200	2	is	be	AUX
fnp-3671	200	3	an	an	DET
fnp-3671	200	4	open	open	ADJ
fnp-3671	200	5	access	access	NOUN
fnp-3671	200	6	article	article	NOUN
fnp-3671	200	7	distributed	distribute	VERB
fnp-3671	200	8	under	under	ADP
fnp-3671	200	9	the	the	DET
fnp-3671	200	10	terms	term	NOUN
fnp-3671	200	11	of	of	ADP
fnp-3671	200	12	the	the	DET
fnp-3671	200	13	creative	creative	ADJ
fnp-3671	200	14	commons	common	NOUN
fnp-3671	200	15	attribution	attribution	NOUN
fnp-3671	200	16	4.0	4.0	NUM
fnp-3671	200	17	international	international	ADJ
fnp-3671	200	18	license	license	NOUN
fnp-3671	200	19	(	(	PUNCT
fnp-3671	200	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3671	200	21	)	)	PUNCT
fnp-3671	200	22	,	,	PUNCT
fnp-3671	200	23	which	which	PRON
fnp-3671	200	24	permits	permit	VERB
fnp-3671	200	25	unrestricted	unrestricted	ADJ
fnp-3671	200	26	use	use	NOUN
fnp-3671	200	27	,	,	PUNCT
fnp-3671	200	28	distribution	distribution	NOUN
fnp-3671	200	29	,	,	PUNCT
fnp-3671	200	30	and	and	CCONJ
fnp-3671	200	31	reproduction	reproduction	NOUN
fnp-3671	200	32	in	in	ADP
fnp-3671	200	33	any	any	DET
fnp-3671	200	34	medium	medium	NOUN
fnp-3671	200	35	,	,	PUNCT
fnp-3671	200	36	provided	provide	VERB
fnp-3671	200	37	the	the	DET
fnp-3671	200	38	original	original	ADJ
fnp-3671	200	39	author	author	NOUN
fnp-3671	200	40	and	and	CCONJ
fnp-3671	200	41	source	source	NOUN
fnp-3671	200	42	are	be	AUX
fnp-3671	200	43	credited	credit	VERB
fnp-3671	200	44	,	,	PUNCT
fnp-3671	200	45	a	a	DET
fnp-3671	200	46	link	link	NOUN
fnp-3671	200	47	to	to	ADP
fnp-3671	200	48	the	the	DET
fnp-3671	200	49	creative	creative	ADJ
fnp-3671	200	50	commons	common	NOUN
fnp-3671	200	51	license	license	NOUN
fnp-3671	200	52	is	be	AUX
fnp-3671	200	53	provided	provide	VERB
fnp-3671	200	54	,	,	PUNCT
fnp-3671	200	55	and	and	CCONJ
fnp-3671	200	56	any	any	DET
fnp-3671	200	57	changes	change	NOUN
fnp-3671	200	58	are	be	AUX
fnp-3671	200	59	indicated	indicate	VERB
fnp-3671	200	60	.	.	PUNCT
fnp-3671	201	1	the	the	DET
fnp-3671	201	2	creative	creative	ADJ
fnp-3671	201	3	commons	common	NOUN
fnp-3671	201	4	public	public	ADJ
fnp-3671	201	5	domain	domain	NOUN
fnp-3671	201	6	dedication	dedication	NOUN
fnp-3671	201	7	waiver	waiver	NOUN
fnp-3671	201	8	(	(	PUNCT
fnp-3671	201	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3671	201	10	)	)	PUNCT
fnp-3671	201	11	applies	apply	VERB
fnp-3671	201	12	to	to	ADP
fnp-3671	201	13	the	the	DET
fnp-3671	201	14	data	datum	NOUN
fnp-3671	201	15	made	make	VERB
fnp-3671	201	16	available	available	ADJ
fnp-3671	201	17	in	in	ADP
fnp-3671	201	18	this	this	DET
fnp-3671	201	19	article	article	NOUN
fnp-3671	201	20	,	,	PUNCT
fnp-3671	201	21	unless	unless	SCONJ
fnp-3671	201	22	otherwise	otherwise	ADV
fnp-3671	201	23	stated	state	VERB
fnp-3671	201	24	.	.	PUNCT
