id	sid	tid	token	lemma	pos
fnp-3679	1	1	friedreich	friedreich	NOUN
fnp-3679	1	2	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	1	3	is	be	AUX
fnp-3679	1	4	a	a	DET
fnp-3679	1	5	desminopathy	desminopathy	ADJ
fnp-3679	1	6	feel	feel	VERB
fnp-3679	1	7	free	free	ADJ
fnp-3679	1	8	to	to	PART
fnp-3679	1	9	add	add	VERB
fnp-3679	1	10	comments	comment	NOUN
fnp-3679	1	11	by	by	ADP
fnp-3679	1	12	clicking	click	VERB
fnp-3679	1	13	these	these	DET
fnp-3679	1	14	icons	icon	NOUN
fnp-3679	1	15	on	on	ADP
fnp-3679	1	16	the	the	DET
fnp-3679	1	17	sidebar	sidebar	NOUN
fnp-3679	1	18	free	free	ADJ
fnp-3679	1	19	neuropathology	neuropathology	NOUN
fnp-3679	1	20	2:34	2:34	NUM
fnp-3679	1	21	(	(	PUNCT
fnp-3679	1	22	2021	2021	NUM
fnp-3679	1	23	)	)	PUNCT
fnp-3679	1	24	original	original	ADJ
fnp-3679	1	25	paper	paper	NOUN
fnp-3679	1	26	friedreich	friedreich	NOUN
fnp-3679	1	27	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	1	28	is	be	AUX
fnp-3679	1	29	a	a	DET
fnp-3679	1	30	desminopathy	desminopathy	ADJ
fnp-3679	1	31	arnulf	arnulf	NOUN
fnp-3679	1	32	h.	h.	PROPN
fnp-3679	1	33	koeppen1,2	koeppen1,2	PROPN
fnp-3679	1	34	,	,	PUNCT
fnp-3679	1	35	rahman	rahman	PROPN
fnp-3679	1	36	f.	f.	PROPN
fnp-3679	1	37	rafique1	rafique1	PROPN
fnp-3679	1	38	,	,	PUNCT
fnp-3679	1	39	joseph	joseph	PROPN
fnp-3679	1	40	e.	e.	PROPN
fnp-3679	1	41	mazurkiewicz3	mazurkiewicz3	PROPN
fnp-3679	1	42	,	,	PUNCT
fnp-3679	1	43	steven	steven	PROPN
fnp-3679	1	44	pelech4,5	pelech4,5	PROPN
fnp-3679	1	45	,	,	PUNCT
fnp-3679	1	46	catherine	catherine	PROPN
fnp-3679	1	47	sutter4	sutter4	PROPN
fnp-3679	1	48	,	,	PUNCT
fnp-3679	1	49	qishan	qishan	PROPN
fnp-3679	1	50	lin6	lin6	PROPN
fnp-3679	1	51	,	,	PUNCT
fnp-3679	1	52	jiang	jiang	PROPN
fnp-3679	1	53	qian7	qian7	VERB
fnp-3679	1	54	1	1	NUM
fnp-3679	1	55	research	research	NOUN
fnp-3679	1	56	service	service	NOUN
fnp-3679	1	57	,	,	PUNCT
fnp-3679	1	58	veterans	veterans	PROPN
fnp-3679	1	59	affairs	affairs	PROPN
fnp-3679	1	60	medical	medical	ADJ
fnp-3679	1	61	center	center	PROPN
fnp-3679	1	62	,	,	PUNCT
fnp-3679	1	63	albany	albany	PROPN
fnp-3679	1	64	,	,	PUNCT
fnp-3679	1	65	ny	ny	PROPN
fnp-3679	1	66	,	,	PUNCT
fnp-3679	1	67	usa	usa	PROPN
fnp-3679	1	68	2	2	NUM
fnp-3679	1	69	departments	department	NOUN
fnp-3679	1	70	of	of	ADP
fnp-3679	1	71	neurology	neurology	NOUN
fnp-3679	1	72	and	and	CCONJ
fnp-3679	1	73	pathology	pathology	NOUN
fnp-3679	1	74	,	,	PUNCT
fnp-3679	1	75	albany	albany	PROPN
fnp-3679	1	76	medical	medical	PROPN
fnp-3679	1	77	college	college	PROPN
fnp-3679	1	78	,	,	PUNCT
fnp-3679	1	79	albany	albany	PROPN
fnp-3679	1	80	,	,	PUNCT
fnp-3679	1	81	ny	ny	PROPN
fnp-3679	1	82	,	,	PUNCT
fnp-3679	1	83	usa	usa	PROPN
fnp-3679	1	84	3	3	NUM
fnp-3679	1	85	department	department	NOUN
fnp-3679	1	86	of	of	ADP
fnp-3679	1	87	neuroscience	neuroscience	NOUN
fnp-3679	1	88	and	and	CCONJ
fnp-3679	1	89	experimental	experimental	ADJ
fnp-3679	1	90	therapeutics	therapeutic	NOUN
fnp-3679	1	91	,	,	PUNCT
fnp-3679	1	92	albany	albany	PROPN
fnp-3679	1	93	medical	medical	PROPN
fnp-3679	1	94	college	college	PROPN
fnp-3679	1	95	,	,	PUNCT
fnp-3679	1	96	albany	albany	PROPN
fnp-3679	1	97	,	,	PUNCT
fnp-3679	1	98	ny	ny	PROPN
fnp-3679	1	99	,	,	PUNCT
fnp-3679	1	100	usa	usa	PROPN
fnp-3679	1	101	4	4	NUM
fnp-3679	1	102	kinexus	kinexus	NOUN
fnp-3679	1	103	bioinformatics	bioinformatics	NOUN
fnp-3679	1	104	corporation	corporation	NOUN
fnp-3679	1	105	,	,	PUNCT
fnp-3679	1	106	vancouver	vancouver	PROPN
fnp-3679	1	107	,	,	PUNCT
fnp-3679	1	108	bc	bc	PROPN
fnp-3679	1	109	,	,	PUNCT
fnp-3679	1	110	canada	canada	PROPN
fnp-3679	1	111	5	5	NUM
fnp-3679	1	112	department	department	NOUN
fnp-3679	1	113	of	of	ADP
fnp-3679	1	114	medicine	medicine	NOUN
fnp-3679	1	115	,	,	PUNCT
fnp-3679	1	116	university	university	NOUN
fnp-3679	1	117	of	of	ADP
fnp-3679	1	118	british	british	PROPN
fnp-3679	1	119	columbia	columbia	PROPN
fnp-3679	1	120	,	,	PUNCT
fnp-3679	1	121	vancouver	vancouver	PROPN
fnp-3679	1	122	,	,	PUNCT
fnp-3679	1	123	bc	bc	PROPN
fnp-3679	1	124	,	,	PUNCT
fnp-3679	1	125	canada	canada	PROPN
fnp-3679	1	126	6	6	NUM
fnp-3679	1	127	rna	rna	PROPN
fnp-3679	1	128	epitranscriptomic	epitranscriptomic	PROPN
fnp-3679	1	129	&	&	CCONJ
fnp-3679	1	130	proteomics	proteomic	NOUN
fnp-3679	1	131	resource	resource	NOUN
fnp-3679	1	132	,	,	PUNCT
fnp-3679	1	133	university	university	NOUN
fnp-3679	1	134	at	at	ADP
fnp-3679	1	135	albany	albany	PROPN
fnp-3679	1	136	,	,	PUNCT
fnp-3679	1	137	albany	albany	PROPN
fnp-3679	1	138	,	,	PUNCT
fnp-3679	1	139	ny	ny	PROPN
fnp-3679	1	140	,	,	PUNCT
fnp-3679	1	141	usa	usa	PROPN
fnp-3679	1	142	7	7	NUM
fnp-3679	1	143	department	department	PROPN
fnp-3679	1	144	of	of	ADP
fnp-3679	1	145	pathology	pathology	PROPN
fnp-3679	1	146	,	,	PUNCT
fnp-3679	1	147	albany	albany	PROPN
fnp-3679	1	148	medical	medical	PROPN
fnp-3679	1	149	college	college	PROPN
fnp-3679	1	150	,	,	PUNCT
fnp-3679	1	151	albany	albany	PROPN
fnp-3679	1	152	,	,	PUNCT
fnp-3679	1	153	ny	ny	PROPN
fnp-3679	1	154	,	,	PUNCT
fnp-3679	1	155	usa	usa	PROPN
fnp-3679	1	156	corresponding	corresponding	PROPN
fnp-3679	1	157	author	author	NOUN
fnp-3679	1	158	:	:	PUNCT
fnp-3679	1	159	arnulf	arnulf	PROPN
fnp-3679	1	160	h	h	PROPN
fnp-3679	1	161	koeppen	koeppen	PROPN
fnp-3679	1	162	,	,	PUNCT
fnp-3679	1	163	md	md	PROPN
fnp-3679	1	164	·	·	PUNCT
fnp-3679	1	165	research	research	NOUN
fnp-3679	1	166	service	service	NOUN
fnp-3679	1	167	(	(	PUNCT
fnp-3679	1	168	151	151	NUM
fnp-3679	1	169	)	)	PUNCT
fnp-3679	1	170	·	·	PUNCT
fnp-3679	1	171	va	va	PROPN
fnp-3679	1	172	medical	medical	ADJ
fnp-3679	1	173	center	center	NOUN
fnp-3679	1	174	·	·	PUNCT
fnp-3679	1	175	113	113	NUM
fnp-3679	1	176	holland	holland	PROPN
fnp-3679	1	177	ave	ave	PROPN
fnp-3679	1	178	·	·	PUNCT
fnp-3679	1	179	albany	albany	PROPN
fnp-3679	1	180	,	,	PUNCT
fnp-3679	1	181	ny	ny	PROPN
fnp-3679	1	182	·	·	PUNCT
fnp-3679	1	183	12208	12208	NUM
fnp-3679	1	184	,	,	PUNCT
fnp-3679	1	185	usa	usa	PROPN
fnp-3679	1	186	arnulf.koeppen@med.va.gov	arnulf.koeppen@med.va.gov	PROPN
fnp-3679	1	187	submitted	submit	VERB
fnp-3679	1	188	:	:	PUNCT
fnp-3679	1	189	11	11	NUM
fnp-3679	1	190	november	november	PROPN
fnp-3679	1	191	2021	2021	NUM
fnp-3679	1	192	accepted	accept	VERB
fnp-3679	1	193	:	:	PUNCT
fnp-3679	1	194	08	08	NUM
fnp-3679	1	195	december	december	PROPN
fnp-3679	1	196	2021	2021	NUM
fnp-3679	1	197	copyedited	copyedit	VERB
fnp-3679	1	198	by	by	ADP
fnp-3679	1	199	:	:	PUNCT
fnp-3679	1	200	vanessa	vanessa	PROPN
fnp-3679	1	201	s.	s.	PROPN
fnp-3679	1	202	goodwill	goodwill	PROPN
fnp-3679	1	203	published	publish	VERB
fnp-3679	1	204	:	:	PUNCT
fnp-3679	1	205	13	13	NUM
fnp-3679	1	206	december	december	NOUN
fnp-3679	1	207	2021	2021	NUM
fnp-3679	2	1	https://doi.org/10.17879/freeneuropathology-2021-3679	https://doi.org/10.17879/freeneuropathology-2021-3679	PROPN
fnp-3679	2	2	keywords	keyword	NOUN
fnp-3679	2	3	:	:	PUNCT
fnp-3679	2	4	friedreich	friedreich	NOUN
fnp-3679	2	5	ataxia	ataxia	NOUN
fnp-3679	2	6	,	,	PUNCT
fnp-3679	2	7	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	2	8	,	,	PUNCT
fnp-3679	2	9	proteomics	proteomic	NOUN
fnp-3679	2	10	,	,	PUNCT
fnp-3679	2	11	desmin	desmin	ADJ
fnp-3679	2	12	,	,	PUNCT
fnp-3679	2	13	αb	αb	NOUN
fnp-3679	2	14	-	-	PUNCT
fnp-3679	2	15	crystallin	crystallin	NOUN
fnp-3679	2	16	,	,	PUNCT
fnp-3679	2	17	desminopathy	desminopathy	ADJ
fnp-3679	2	18	abstract	abstract	ADJ
fnp-3679	2	19	heart	heart	NOUN
fnp-3679	2	20	disease	disease	NOUN
fnp-3679	2	21	is	be	AUX
fnp-3679	2	22	an	an	DET
fnp-3679	2	23	integral	integral	ADJ
fnp-3679	2	24	part	part	NOUN
fnp-3679	2	25	of	of	ADP
fnp-3679	2	26	friedreich	friedreich	NOUN
fnp-3679	2	27	ataxia	ataxia	NOUN
fnp-3679	2	28	(	(	PUNCT
fnp-3679	2	29	fa	fa	NOUN
fnp-3679	2	30	)	)	PUNCT
fnp-3679	2	31	and	and	CCONJ
fnp-3679	2	32	the	the	DET
fnp-3679	2	33	most	most	ADV
fnp-3679	2	34	common	common	ADJ
fnp-3679	2	35	cause	cause	NOUN
fnp-3679	2	36	of	of	ADP
fnp-3679	2	37	death	death	NOUN
fnp-3679	2	38	in	in	ADP
fnp-3679	2	39	this	this	DET
fnp-3679	2	40	autosomal	autosomal	ADJ
fnp-3679	2	41	recessive	recessive	ADJ
fnp-3679	2	42	disease	disease	NOUN
fnp-3679	2	43	.	.	PUNCT
fnp-3679	3	1	the	the	DET
fnp-3679	3	2	result	result	NOUN
fnp-3679	3	3	of	of	ADP
fnp-3679	3	4	the	the	DET
fnp-3679	3	5	mutation	mutation	NOUN
fnp-3679	3	6	is	be	AUX
fnp-3679	3	7	lack	lack	NOUN
fnp-3679	3	8	of	of	ADP
fnp-3679	3	9	frataxin	frataxin	NOUN
fnp-3679	3	10	,	,	PUNCT
fnp-3679	3	11	a	a	DET
fnp-3679	3	12	small	small	ADJ
fnp-3679	3	13	mitochondrial	mitochondrial	ADJ
fnp-3679	3	14	protein	protein	NOUN
fnp-3679	3	15	.	.	PUNCT
fnp-3679	4	1	the	the	DET
fnp-3679	4	2	clinical	clinical	ADJ
fnp-3679	4	3	and	and	CCONJ
fnp-3679	4	4	pathological	pathological	ADJ
fnp-3679	4	5	phenotypes	phenotype	NOUN
fnp-3679	4	6	of	of	ADP
fnp-3679	4	7	fa	fa	PROPN
fnp-3679	4	8	are	be	AUX
fnp-3679	4	9	complex	complex	ADJ
fnp-3679	4	10	,	,	PUNCT
fnp-3679	4	11	involving	involve	VERB
fnp-3679	4	12	brain	brain	NOUN
fnp-3679	4	13	,	,	PUNCT
fnp-3679	4	14	spinal	spinal	ADJ
fnp-3679	4	15	cord	cord	NOUN
fnp-3679	4	16	,	,	PUNCT
fnp-3679	4	17	dorsal	dorsal	NOUN
fnp-3679	4	18	root	root	NOUN
fnp-3679	4	19	ganglia	ganglia	NOUN
fnp-3679	4	20	,	,	PUNCT
fnp-3679	4	21	sensory	sensory	ADJ
fnp-3679	4	22	nerves	nerve	NOUN
fnp-3679	4	23	,	,	PUNCT
fnp-3679	4	24	heart	heart	NOUN
fnp-3679	4	25	,	,	PUNCT
fnp-3679	4	26	and	and	CCONJ
fnp-3679	4	27	endocrine	endocrine	ADJ
fnp-3679	4	28	pancreas	pancrea	NOUN
fnp-3679	4	29	.	.	PUNCT
fnp-3679	5	1	the	the	DET
fnp-3679	5	2	hypothesis	hypothesis	NOUN
fnp-3679	5	3	is	be	AUX
fnp-3679	5	4	that	that	SCONJ
fnp-3679	5	5	frataxin	frataxin	NOUN
fnp-3679	5	6	deficiency	deficiency	NOUN
fnp-3679	5	7	causes	cause	VERB
fnp-3679	5	8	downstream	downstream	ADJ
fnp-3679	5	9	changes	change	NOUN
fnp-3679	5	10	in	in	ADP
fnp-3679	5	11	the	the	DET
fnp-3679	5	12	proteome	proteome	NOUN
fnp-3679	5	13	of	of	ADP
fnp-3679	5	14	the	the	DET
fnp-3679	5	15	affected	affected	ADJ
fnp-3679	5	16	tissues	tissue	NOUN
fnp-3679	5	17	,	,	PUNCT
fnp-3679	5	18	including	include	VERB
fnp-3679	5	19	the	the	DET
fnp-3679	5	20	heart	heart	NOUN
fnp-3679	5	21	.	.	PUNCT
fnp-3679	6	1	a	a	DET
fnp-3679	6	2	proteomic	proteomic	ADJ
fnp-3679	6	3	analysis	analysis	NOUN
fnp-3679	6	4	of	of	ADP
fnp-3679	6	5	heart	heart	NOUN
fnp-3679	6	6	proteins	protein	NOUN
fnp-3679	6	7	in	in	ADP
fnp-3679	6	8	fa	fa	NOUN
fnp-3679	6	9	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	6	10	by	by	ADP
fnp-3679	6	11	antibody	antibody	NOUN
fnp-3679	6	12	microarray	microarray	NOUN
fnp-3679	6	13	,	,	PUNCT
fnp-3679	6	14	western	western	ADJ
fnp-3679	6	15	blots	blot	NOUN
fnp-3679	6	16	,	,	PUNCT
fnp-3679	6	17	immunohistochemistry	immunohistochemistry	NOUN
fnp-3679	6	18	,	,	PUNCT
fnp-3679	6	19	and	and	CCONJ
fnp-3679	6	20	double	double	ADJ
fnp-3679	6	21	-	-	PUNCT
fnp-3679	6	22	label	label	NOUN
fnp-3679	6	23	laser	laser	NOUN
fnp-3679	6	24	scanning	scan	VERB
fnp-3679	6	25	confocal	confocal	ADJ
fnp-3679	6	26	immunofluorescence	immunofluorescence	NOUN
fnp-3679	6	27	microscopy	microscopy	NOUN
fnp-3679	6	28	revealed	reveal	VERB
fnp-3679	6	29	upregulation	upregulation	NOUN
fnp-3679	6	30	of	of	ADP
fnp-3679	6	31	desmin	desmin	PROPN
fnp-3679	6	32	and	and	CCONJ
fnp-3679	6	33	its	its	PRON
fnp-3679	6	34	chaperone	chaperone	NOUN
fnp-3679	6	35	protein	protein	NOUN
fnp-3679	6	36	,	,	PUNCT
fnp-3679	6	37	αb	αb	NOUN
fnp-3679	6	38	-	-	PUNCT
fnp-3679	6	39	crystallin	crystallin	NOUN
fnp-3679	6	40	.	.	PUNCT
fnp-3679	7	1	in	in	ADP
fnp-3679	7	2	normal	normal	ADJ
fnp-3679	7	3	hearts	heart	NOUN
fnp-3679	7	4	,	,	PUNCT
fnp-3679	7	5	these	these	DET
fnp-3679	7	6	two	two	NUM
fnp-3679	7	7	proteins	protein	NOUN
fnp-3679	7	8	are	be	AUX
fnp-3679	7	9	co	co	ADJ
fnp-3679	7	10	-	-	VERB
fnp-3679	7	11	localized	localize	VERB
fnp-3679	7	12	at	at	ADP
fnp-3679	7	13	intercalated	intercalate	VERB
fnp-3679	7	14	discs	disc	NOUN
fnp-3679	7	15	and	and	CCONJ
fnp-3679	7	16	z	z	NOUN
fnp-3679	7	17	discs	disc	NOUN
fnp-3679	7	18	.	.	PUNCT
fnp-3679	8	1	in	in	ADP
fnp-3679	8	2	fa	fa	PROPN
fnp-3679	8	3	,	,	PUNCT
fnp-3679	8	4	desmin	desmin	ADJ
fnp-3679	8	5	and	and	CCONJ
fnp-3679	8	6	αb	αb	NOUN
fnp-3679	8	7	-	-	PUNCT
fnp-3679	8	8	crystallin	crystallin	NOUN
fnp-3679	8	9	aggregate	aggregate	NOUN
fnp-3679	8	10	,	,	PUNCT
fnp-3679	8	11	causing	cause	VERB
fnp-3679	8	12	chaotic	chaotic	ADJ
fnp-3679	8	13	modification	modification	NOUN
fnp-3679	8	14	of	of	ADP
fnp-3679	8	15	intercalated	intercalated	ADJ
fnp-3679	8	16	discs	disc	NOUN
fnp-3679	8	17	,	,	PUNCT
fnp-3679	8	18	clustering	clustering	NOUN
fnp-3679	8	19	of	of	ADP
fnp-3679	8	20	mitochondria	mitochondria	NOUN
fnp-3679	8	21	,	,	PUNCT
fnp-3679	8	22	and	and	CCONJ
fnp-3679	8	23	destruction	destruction	NOUN
fnp-3679	8	24	of	of	ADP
fnp-3679	8	25	the	the	DET
fnp-3679	8	26	contractile	contractile	NOUN
fnp-3679	8	27	apparatus	apparatus	NOUN
fnp-3679	8	28	of	of	ADP
fnp-3679	8	29	cardiomyocytes	cardiomyocyte	NOUN
fnp-3679	8	30	.	.	PUNCT
fnp-3679	9	1	western	western	ADJ
fnp-3679	9	2	blots	blot	NOUN
fnp-3679	9	3	of	of	ADP
fnp-3679	9	4	tissue	tissue	NOUN
fnp-3679	9	5	lysates	lysate	NOUN
fnp-3679	9	6	in	in	ADP
fnp-3679	9	7	fa	fa	PROPN
fnp-3679	9	8	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	9	9	reveal	reveal	VERB
fnp-3679	9	10	a	a	DET
fnp-3679	9	11	truncated	truncate	VERB
fnp-3679	9	12	desmin	desmin	NOUN
fnp-3679	9	13	isoprotein	isoprotein	ADP
fnp-3679	9	14	that	that	PRON
fnp-3679	9	15	migrates	migrate	VERB
fnp-3679	9	16	at	at	ADP
fnp-3679	9	17	a	a	DET
fnp-3679	9	18	lower	low	ADJ
fnp-3679	9	19	molecular	molecular	ADJ
fnp-3679	9	20	weight	weight	NOUN
fnp-3679	9	21	range	range	NOUN
fnp-3679	9	22	than	than	ADP
fnp-3679	9	23	wild	wild	ADJ
fnp-3679	9	24	type	type	NOUN
fnp-3679	9	25	desmin	desmin	NOUN
fnp-3679	9	26	.	.	PUNCT
fnp-3679	10	1	while	while	SCONJ
fnp-3679	10	2	desmin	desmin	ADJ
fnp-3679	10	3	and	and	CCONJ
fnp-3679	10	4	αb	αb	PROPN
fnp-3679	10	5	-	-	PUNCT
fnp-3679	10	6	crystallin	crystallin	NOUN
fnp-3679	10	7	are	be	AUX
fnp-3679	10	8	not	not	PART
fnp-3679	10	9	mutated	mutate	VERB
fnp-3679	10	10	in	in	ADP
fnp-3679	10	11	fa	fa	PROPN
fnp-3679	10	12	,	,	PUNCT
fnp-3679	10	13	the	the	DET
fnp-3679	10	14	accumulation	accumulation	NOUN
fnp-3679	10	15	of	of	ADP
fnp-3679	10	16	these	these	DET
fnp-3679	10	17	proteins	protein	NOUN
fnp-3679	10	18	in	in	ADP
fnp-3679	10	19	fa	fa	PROPN
fnp-3679	10	20	hearts	heart	NOUN
fnp-3679	10	21	allows	allow	VERB
fnp-3679	10	22	the	the	DET
fnp-3679	10	23	conclusion	conclusion	NOUN
fnp-3679	10	24	that	that	SCONJ
fnp-3679	10	25	fa	fa	PROPN
fnp-3679	10	26	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	10	27	is	be	AUX
fnp-3679	10	28	a	a	DET
fnp-3679	10	29	desminopathy	desminopathy	ADJ
fnp-3679	10	30	akin	akin	ADJ
fnp-3679	10	31	to	to	ADP
fnp-3679	10	32	desmin	desmin	ADJ
fnp-3679	10	33	myopathy	myopathy	ADJ
fnp-3679	10	34	of	of	ADP
fnp-3679	10	35	skeletal	skeletal	ADJ
fnp-3679	10	36	muscle	muscle	NOUN
fnp-3679	10	37	.	.	PUNCT
fnp-3679	11	1	introduction	introduction	NOUN
fnp-3679	11	2	heart	heart	NOUN
fnp-3679	11	3	disease	disease	NOUN
fnp-3679	11	4	in	in	ADP
fnp-3679	11	5	friedreich	friedreich	PROPN
fnp-3679	11	6	ataxia	ataxia	NOUN
fnp-3679	11	7	(	(	PUNCT
fnp-3679	11	8	fa	fa	NOUN
fnp-3679	11	9	)	)	PUNCT
fnp-3679	11	10	,	,	PUNCT
fnp-3679	11	11	hereafter	hereafter	ADV
fnp-3679	11	12	called	call	VERB
fnp-3679	11	13	fa	fa	NOUN
fnp-3679	11	14	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	11	15	,	,	PUNCT
fnp-3679	11	16	is	be	AUX
fnp-3679	11	17	the	the	DET
fnp-3679	11	18	most	most	ADV
fnp-3679	11	19	common	common	ADJ
fnp-3679	11	20	cause	cause	NOUN
fnp-3679	11	21	of	of	ADP
fnp-3679	11	22	death	death	NOUN
fnp-3679	11	23	in	in	ADP
fnp-3679	11	24	this	this	DET
fnp-3679	11	25	otherwise	otherwise	ADV
fnp-3679	11	26	rather	rather	ADV
fnp-3679	11	27	neurological	neurological	ADJ
fnp-3679	11	28	disease	disease	NOUN
fnp-3679	11	29	.	.	PUNCT
fnp-3679	12	1	fa	fa	X
fnp-3679	12	2	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	12	3	was	be	AUX
fnp-3679	12	4	introduced	introduce	VERB
fnp-3679	12	5	as	as	ADP
fnp-3679	12	6	an	an	DET
fnp-3679	12	7	integral	integral	ADJ
fnp-3679	12	8	part	part	NOUN
fnp-3679	12	9	of	of	ADP
fnp-3679	12	10	fa	fa	INTJ
fnp-3679	12	11	by	by	ADP
fnp-3679	12	12	russell	russell	PROPN
fnp-3679	12	13	(	(	PUNCT
fnp-3679	12	14	1946	1946	NUM
fnp-3679	12	15	)	)	PUNCT
fnp-3679	12	16	,	,	PUNCT
fnp-3679	12	17	and	and	CCONJ
fnp-3679	12	18	there	there	PRON
fnp-3679	12	19	is	be	VERB
fnp-3679	12	20	no	no	DET
fnp-3679	12	21	doubt	doubt	NOUN
fnp-3679	12	22	that	that	SCONJ
fnp-3679	12	23	the	the	DET
fnp-3679	12	24	cardiac	cardiac	ADJ
fnp-3679	12	25	lesion	lesion	NOUN
fnp-3679	12	26	is	be	AUX
fnp-3679	12	27	due	due	ADJ
fnp-3679	12	28	to	to	ADP
fnp-3679	12	29	frataxin	frataxin	ADJ
fnp-3679	12	30	deficiency	deficiency	NOUN
fnp-3679	12	31	(	(	PUNCT
fnp-3679	12	32	perdomini	perdomini	NOUN
fnp-3679	12	33	et	et	PROPN
fnp-3679	12	34	al	al	PROPN
fnp-3679	12	35	.	.	PROPN
fnp-3679	12	36	,	,	PUNCT
fnp-3679	12	37	2014	2014	NUM
fnp-3679	12	38	)	)	PUNCT
fnp-3679	12	39	.	.	PUNCT
fnp-3679	13	1	under	under	ADP
fnp-3679	13	2	the	the	DET
fnp-3679	13	3	microscope	microscope	NOUN
fnp-3679	13	4	,	,	PUNCT
fnp-3679	13	5	sections	section	NOUN
fnp-3679	13	6	of	of	ADP
fnp-3679	13	7	fa	fa	NOUN
fnp-3679	13	8	heart	heart	NOUN
fnp-3679	13	9	show	show	VERB
fnp-3679	13	10	multiple	multiple	ADJ
fnp-3679	13	11	abnormalities	abnormality	NOUN
fnp-3679	13	12	,	,	PUNCT
fnp-3679	13	13	including	include	VERB
fnp-3679	13	14	fiber	fiber	NOUN
fnp-3679	13	15	hypertrophy	hypertrophy	NOUN
fnp-3679	13	16	(	(	PUNCT
fnp-3679	13	17	koeppen	koeppen	PROPN
fnp-3679	13	18	et	et	PROPN
fnp-3679	13	19	al	al	PROPN
fnp-3679	13	20	.	.	PROPN
fnp-3679	13	21	,	,	PUNCT
fnp-3679	13	22	2015	2015	NUM
fnp-3679	13	23	)	)	PUNCT
fnp-3679	13	24	,	,	PUNCT
fnp-3679	13	25	fiber	fiber	NOUN
fnp-3679	13	26	necrosis	necrosis	NOUN
fnp-3679	13	27	,	,	PUNCT
fnp-3679	13	28	fibrosis	fibrosis	NOUN
fnp-3679	13	29	,	,	PUNCT
fnp-3679	13	30	inflammatory	inflammatory	ADJ
fnp-3679	13	31	infiltration	infiltration	NOUN
fnp-3679	13	32	,	,	PUNCT
fnp-3679	13	33	chaotic	chaotic	ADJ
fnp-3679	13	34	disorganization	disorganization	NOUN
fnp-3679	13	35	of	of	ADP
fnp-3679	13	36	intercalated	intercalated	ADJ
fnp-3679	13	37	discs	disc	NOUN
fnp-3679	13	38	,	,	PUNCT
fnp-3679	13	39	and	and	CCONJ
fnp-3679	13	40	accumulation	accumulation	NOUN
fnp-3679	13	41	of	of	ADP
fnp-3679	13	42	iron	iron	NOUN
fnp-3679	13	43	in	in	ADP
fnp-3679	13	44	a	a	DET
fnp-3679	13	45	small	small	ADJ
fnp-3679	13	46	percentage	percentage	NOUN
fnp-3679	13	47	of	of	ADP
fnp-3679	13	48	cardiomyocytes	cardiomyocyte	NOUN
fnp-3679	13	49	without	without	ADP
fnp-3679	13	50	iron	iron	NOUN
fnp-3679	13	51	excess	excess	NOUN
fnp-3679	13	52	in	in	ADP
fnp-3679	13	53	the	the	DET
fnp-3679	13	54	whole	whole	ADJ
fnp-3679	13	55	heart	heart	NOUN
fnp-3679	13	56	(	(	PUNCT
fnp-3679	13	57	ramirez	ramirez	PROPN
fnp-3679	13	58	et	et	PROPN
fnp-3679	13	59	al	al	PROPN
fnp-3679	13	60	.	.	PROPN
fnp-3679	13	61	,	,	PUNCT
fnp-3679	13	62	2012	2012	NUM
fnp-3679	13	63	;	;	PUNCT
fnp-3679	13	64	kruger	kruger	PROPN
fnp-3679	13	65	et	et	PROPN
fnp-3679	13	66	al	al	PROPN
fnp-3679	13	67	.	.	PROPN
fnp-3679	13	68	,	,	PUNCT
fnp-3679	13	69	2016	2016	NUM
fnp-3679	13	70	)	)	PUNCT
fnp-3679	13	71	.	.	PUNCT
fnp-3679	14	1	the	the	DET
fnp-3679	14	2	reason	reason	NOUN
fnp-3679	14	3	for	for	ADP
fnp-3679	14	4	the	the	DET
fnp-3679	14	5	highly	highly	ADV
fnp-3679	14	6	variable	variable	ADJ
fnp-3679	14	7	pathological	pathological	ADJ
fnp-3679	14	8	phenotype	phenotype	NOUN
fnp-3679	14	9	of	of	ADP
fnp-3679	14	10	fa	fa	PROPN
fnp-3679	14	11	as	as	SCONJ
fnp-3679	14	12	it	it	PRON
fnp-3679	14	13	affects	affect	VERB
fnp-3679	14	14	heart	heart	NOUN
fnp-3679	14	15	,	,	PUNCT
fnp-3679	14	16	central	central	ADJ
fnp-3679	14	17	and	and	CCONJ
fnp-3679	14	18	peripheral	peripheral	ADJ
fnp-3679	14	19	nervous	nervous	ADJ
fnp-3679	14	20	systems	system	NOUN
fnp-3679	14	21	,	,	PUNCT
fnp-3679	14	22	eyes	eye	NOUN
fnp-3679	14	23	,	,	PUNCT
fnp-3679	14	24	and	and	CCONJ
fnp-3679	14	25	endocrine	endocrine	NOUN
fnp-3679	14	26	pancreas	pancreas	NOUN
fnp-3679	14	27	has	have	AUX
fnp-3679	14	28	not	not	PART
fnp-3679	14	29	been	be	AUX
fnp-3679	14	30	fully	fully	ADV
fnp-3679	14	31	established	establish	VERB
fnp-3679	14	32	.	.	PUNCT
fnp-3679	15	1	the	the	DET
fnp-3679	15	2	current	current	ADJ
fnp-3679	15	3	hypothesis	hypothesis	NOUN
fnp-3679	15	4	is	be	AUX
fnp-3679	15	5	that	that	PRON
fnp-3679	15	6	structural	structural	ADJ
fnp-3679	15	7	and	and	CCONJ
fnp-3679	15	8	signaling	signal	VERB
fnp-3679	15	9	proteins	protein	NOUN
fnp-3679	15	10	are	be	AUX
fnp-3679	15	11	affected	affect	VERB
fnp-3679	15	12	downstream	downstream	ADV
fnp-3679	15	13	from	from	ADP
fnp-3679	15	14	cellular	cellular	ADJ
fnp-3679	15	15	frataxin	frataxin	NOUN
fnp-3679	15	16	deficiency	deficiency	NOUN
fnp-3679	15	17	.	.	PUNCT
fnp-3679	16	1	on	on	ADP
fnp-3679	16	2	antibody	antibody	NOUN
fnp-3679	16	3	microarrays	microarray	NOUN
fnp-3679	16	4	and	and	CCONJ
fnp-3679	16	5	western	western	ADJ
fnp-3679	16	6	blots	blot	NOUN
fnp-3679	16	7	,	,	PUNCT
fnp-3679	16	8	desmin	desmin	ADJ
fnp-3679	16	9	and	and	CCONJ
fnp-3679	16	10	its	its	PRON
fnp-3679	16	11	chaperone	chaperone	NOUN
fnp-3679	16	12	,	,	PUNCT
fnp-3679	16	13	αb	αb	NOUN
fnp-3679	16	14	-	-	PUNCT
fnp-3679	16	15	crystallin	crystallin	NOUN
fnp-3679	16	16	,	,	PUNCT
fnp-3679	16	17	are	be	AUX
fnp-3679	16	18	upregulated	upregulate	VERB
fnp-3679	16	19	in	in	ADP
fnp-3679	16	20	fa	fa	PROPN
fnp-3679	16	21	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	16	22	.	.	PUNCT
fnp-3679	17	1	desminopathy	desminopathy	ADJ
fnp-3679	17	2	is	be	AUX
fnp-3679	17	3	well	well	ADV
fnp-3679	17	4	known	know	VERB
fnp-3679	17	5	from	from	ADP
fnp-3679	17	6	the	the	DET
fnp-3679	17	7	study	study	NOUN
fnp-3679	17	8	of	of	ADP
fnp-3679	17	9	desmin	desmin	ADV
fnp-3679	17	10	-	-	PUNCT
fnp-3679	17	11	related	relate	VERB
fnp-3679	17	12	skeletal	skeletal	ADJ
fnp-3679	17	13	myopathies	myopathy	NOUN
fnp-3679	17	14	,	,	PUNCT
fnp-3679	17	15	in	in	ADP
fnp-3679	17	16	which	which	PRON
fnp-3679	17	17	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	17	18	is	be	AUX
fnp-3679	17	19	frequent	frequent	ADJ
fnp-3679	17	20	(	(	PUNCT
fnp-3679	17	21	dalakas	dalakas	PROPN
fnp-3679	17	22	et	et	PROPN
fnp-3679	17	23	al	al	PROPN
fnp-3679	17	24	.	.	PROPN
fnp-3679	17	25	,	,	PUNCT
fnp-3679	17	26	2000	2000	NUM
fnp-3679	17	27	;	;	PUNCT
fnp-3679	17	28	goldfarb	goldfarb	PROPN
fnp-3679	17	29	et	et	PROPN
fnp-3679	17	30	al	al	PROPN
fnp-3679	17	31	.	.	PROPN
fnp-3679	17	32	,	,	PUNCT
fnp-3679	17	33	2004	2004	NUM
fnp-3679	17	34	;	;	PUNCT
fnp-3679	17	35	hnia	hnia	PROPN
fnp-3679	17	36	et	et	PROPN
fnp-3679	17	37	al	al	PROPN
fnp-3679	17	38	.	.	PROPN
fnp-3679	17	39	,	,	PUNCT
fnp-3679	17	40	2015	2015	NUM
fnp-3679	17	41	)	)	PUNCT
fnp-3679	17	42	.	.	PUNCT
fnp-3679	18	1	desmin	desmin	ADJ
fnp-3679	18	2	mutations	mutation	NOUN
fnp-3679	18	3	cause	cause	VERB
fnp-3679	18	4	aggregation	aggregation	NOUN
fnp-3679	18	5	in	in	ADP
fnp-3679	18	6	skeletal	skeletal	ADJ
fnp-3679	18	7	muscle	muscle	NOUN
fnp-3679	18	8	,	,	PUNCT
fnp-3679	18	9	and	and	CCONJ
fnp-3679	18	10	some	some	DET
fnp-3679	18	11	experiments	experiment	NOUN
fnp-3679	18	12	have	have	AUX
fnp-3679	18	13	suggested	suggest	VERB
fnp-3679	18	14	that	that	DET
fnp-3679	18	15	posttranslational	posttranslational	ADJ
fnp-3679	18	16	modifications	modification	NOUN
fnp-3679	18	17	of	of	ADP
fnp-3679	18	18	desmin	desmin	ADJ
fnp-3679	18	19	,	,	PUNCT
fnp-3679	18	20	such	such	ADJ
fnp-3679	18	21	as	as	ADP
fnp-3679	18	22	phosphorylation	phosphorylation	NOUN
fnp-3679	18	23	and	and	CCONJ
fnp-3679	18	24	proteolytic	proteolytic	ADJ
fnp-3679	18	25	fragmentation	fragmentation	NOUN
fnp-3679	18	26	,	,	PUNCT
fnp-3679	18	27	make	make	VERB
fnp-3679	18	28	the	the	DET
fnp-3679	18	29	protein	protein	NOUN
fnp-3679	18	30	amyloidogenic	amyloidogenic	ADJ
fnp-3679	18	31	(	(	PUNCT
fnp-3679	18	32	agnetti	agnetti	PROPN
fnp-3679	18	33	et	et	PROPN
fnp-3679	18	34	al	al	PROPN
fnp-3679	18	35	.	.	PROPN
fnp-3679	18	36	,	,	PUNCT
fnp-3679	18	37	2014	2014	NUM
fnp-3679	18	38	;	;	PUNCT
fnp-3679	18	39	kedia	kedia	PROPN
fnp-3679	18	40	et	et	PROPN
fnp-3679	18	41	al	al	PROPN
fnp-3679	18	42	.	.	PROPN
fnp-3679	18	43	,	,	PUNCT
fnp-3679	18	44	2015	2015	NUM
fnp-3679	18	45	)	)	PUNCT
fnp-3679	18	46	.	.	PUNCT
fnp-3679	19	1	based	base	VERB
fnp-3679	19	2	on	on	ADP
fnp-3679	19	3	the	the	DET
fnp-3679	19	4	observations	observation	NOUN
fnp-3679	19	5	detailed	detail	VERB
fnp-3679	19	6	in	in	ADP
fnp-3679	19	7	this	this	DET
fnp-3679	19	8	report	report	NOUN
fnp-3679	19	9	,	,	PUNCT
fnp-3679	19	10	the	the	DET
fnp-3679	19	11	authors	author	NOUN
fnp-3679	19	12	propose	propose	VERB
fnp-3679	19	13	that	that	SCONJ
fnp-3679	19	14	fa	fa	PROPN
fnp-3679	19	15	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	19	16	is	be	AUX
fnp-3679	19	17	a	a	DET
fnp-3679	19	18	protein	protein	NOUN
fnp-3679	19	19	aggregation	aggregation	NOUN
fnp-3679	19	20	myopathy	myopathy	ADJ
fnp-3679	19	21	involving	involve	VERB
fnp-3679	19	22	desmin	desmin	ADJ
fnp-3679	19	23	and	and	CCONJ
fnp-3679	19	24	αb	αb	NOUN
fnp-3679	19	25	-	-	PUNCT
fnp-3679	19	26	crystallin	crystallin	NOUN
fnp-3679	19	27	.	.	PUNCT
fnp-3679	20	1	in	in	ADP
fnp-3679	20	2	its	its	PRON
fnp-3679	20	3	biogrid	biogrid	ADJ
fnp-3679	20	4	data	data	NOUN
fnp-3679	20	5	base	base	NOUN
fnp-3679	20	6	of	of	ADP
fnp-3679	20	7	protein	protein	NOUN
fnp-3679	20	8	,	,	PUNCT
fnp-3679	20	9	genetic	genetic	ADJ
fnp-3679	20	10	,	,	PUNCT
fnp-3679	20	11	and	and	CCONJ
fnp-3679	20	12	chemical	chemical	NOUN
fnp-3679	20	13	interactions	interaction	NOUN
fnp-3679	20	14	(	(	PUNCT
fnp-3679	20	15	version	version	NOUN
fnp-3679	20	16	4.3.196	4.3.196	NUM
fnp-3679	20	17	)	)	PUNCT
fnp-3679	20	18	,	,	PUNCT
fnp-3679	20	19	uniprot	uniprot	PROPN
fnp-3679	20	20	(	(	PUNCT
fnp-3679	20	21	2021	2021	NUM
fnp-3679	20	22	)	)	PUNCT
fnp-3679	20	23	lists	list	VERB
fnp-3679	20	24	96	96	NUM
fnp-3679	20	25	desmin	desmin	ADV
fnp-3679	20	26	-	-	PUNCT
fnp-3679	20	27	interacting	interact	VERB
fnp-3679	20	28	proteins	protein	NOUN
fnp-3679	20	29	.	.	PUNCT
fnp-3679	21	1	among	among	ADP
fnp-3679	21	2	them	they	PRON
fnp-3679	21	3	,	,	PUNCT
fnp-3679	21	4	αb	αb	PROPN
fnp-3679	21	5	-	-	PUNCT
fnp-3679	21	6	crystallin	crystallin	PROPN
fnp-3679	21	7	is	be	AUX
fnp-3679	21	8	prominently	prominently	ADV
fnp-3679	21	9	recognized	recognize	VERB
fnp-3679	21	10	as	as	ADP
fnp-3679	21	11	a	a	DET
fnp-3679	21	12	desmin	desmin	ADJ
fnp-3679	21	13	partner	partner	NOUN
fnp-3679	21	14	or	or	CCONJ
fnp-3679	21	15	“	"	PUNCT
fnp-3679	21	16	chaperone	chaperone	NOUN
fnp-3679	21	17	”	"	PUNCT
fnp-3679	21	18	.	.	PUNCT
fnp-3679	22	1	indeed	indeed	ADV
fnp-3679	22	2	,	,	PUNCT
fnp-3679	22	3	αb	αb	PROPN
fnp-3679	22	4	-	-	PUNCT
fnp-3679	22	5	crystallin	crystallin	NOUN
fnp-3679	22	6	mutations	mutation	NOUN
fnp-3679	22	7	cause	cause	VERB
fnp-3679	22	8	“	"	PUNCT
fnp-3679	22	9	desmin	desmin	ADJ
fnp-3679	22	10	”	"	PUNCT
fnp-3679	22	11	myopathy	myopathy	ADJ
fnp-3679	22	12	(	(	PUNCT
fnp-3679	22	13	goldfarb	goldfarb	PROPN
fnp-3679	22	14	and	and	CCONJ
fnp-3679	22	15	dalakas	dalakas	PROPN
fnp-3679	22	16	,	,	PUNCT
fnp-3679	22	17	2009	2009	NUM
fnp-3679	22	18	)	)	PUNCT
fnp-3679	22	19	.	.	PUNCT
fnp-3679	23	1	while	while	SCONJ
fnp-3679	23	2	desmin	desmin	NOUN
fnp-3679	23	3	is	be	AUX
fnp-3679	23	4	an	an	DET
fnp-3679	23	5	abundant	abundant	ADJ
fnp-3679	23	6	cytoskeletal	cytoskeletal	ADJ
fnp-3679	23	7	protein	protein	NOUN
fnp-3679	23	8	,	,	PUNCT
fnp-3679	23	9	it	it	PRON
fnp-3679	23	10	also	also	ADV
fnp-3679	23	11	has	have	AUX
fnp-3679	23	12	signaling	signal	VERB
fnp-3679	23	13	properties	property	NOUN
fnp-3679	23	14	,	,	PUNCT
fnp-3679	23	15	and	and	CCONJ
fnp-3679	23	16	the	the	DET
fnp-3679	23	17	term	term	NOUN
fnp-3679	23	18	“	"	PUNCT
fnp-3679	23	19	mechanochemical	mechanochemical	ADJ
fnp-3679	23	20	”	"	PUNCT
fnp-3679	23	21	may	may	AUX
fnp-3679	23	22	be	be	AUX
fnp-3679	23	23	applicable	applicable	ADJ
fnp-3679	23	24	(	(	PUNCT
fnp-3679	23	25	hnia	hnia	NOUN
fnp-3679	23	26	et	et	PROPN
fnp-3679	23	27	al	al	PROPN
fnp-3679	23	28	.	.	PROPN
fnp-3679	23	29	,	,	PUNCT
fnp-3679	23	30	2015	2015	NUM
fnp-3679	23	31	)	)	PUNCT
fnp-3679	23	32	.	.	PUNCT
fnp-3679	24	1	material	material	NOUN
fnp-3679	24	2	and	and	CCONJ
fnp-3679	24	3	methods	method	NOUN
fnp-3679	24	4	autopsy	autopsy	ADJ
fnp-3679	24	5	specimens	specimen	NOUN
fnp-3679	24	6	:	:	PUNCT
fnp-3679	24	7	the	the	DET
fnp-3679	24	8	institutional	institutional	ADJ
fnp-3679	24	9	review	review	NOUN
fnp-3679	24	10	board	board	NOUN
fnp-3679	24	11	of	of	ADP
fnp-3679	24	12	the	the	DET
fnp-3679	24	13	veterans	veterans	PROPN
fnp-3679	24	14	affairs	affairs	PROPN
fnp-3679	24	15	medical	medical	ADJ
fnp-3679	24	16	center	center	PROPN
fnp-3679	24	17	in	in	ADP
fnp-3679	24	18	albany	albany	PROPN
fnp-3679	24	19	,	,	PUNCT
fnp-3679	24	20	ny	ny	PROPN
fnp-3679	24	21	,	,	PUNCT
fnp-3679	24	22	usa	usa	PROPN
fnp-3679	24	23	has	have	AUX
fnp-3679	24	24	approved	approve	VERB
fnp-3679	24	25	this	this	DET
fnp-3679	24	26	investigation	investigation	NOUN
fnp-3679	24	27	.	.	PUNCT
fnp-3679	25	1	heart	heart	NOUN
fnp-3679	25	2	autopsy	autopsy	ADJ
fnp-3679	25	3	specimens	specimen	NOUN
fnp-3679	25	4	were	be	AUX
fnp-3679	25	5	obtained	obtain	VERB
fnp-3679	25	6	from	from	ADP
fnp-3679	25	7	35	35	NUM
fnp-3679	25	8	patients	patient	NOUN
fnp-3679	25	9	with	with	ADP
fnp-3679	25	10	fa	fa	PROPN
fnp-3679	25	11	through	through	ADP
fnp-3679	25	12	a	a	DET
fnp-3679	25	13	national	national	ADJ
fnp-3679	25	14	fa	fa	INTJ
fnp-3679	25	15	tissue	tissue	NOUN
fnp-3679	25	16	repository	repository	NOUN
fnp-3679	25	17	in	in	ADP
fnp-3679	25	18	albany	albany	PROPN
fnp-3679	25	19	,	,	PUNCT
fnp-3679	25	20	ny	ny	PROPN
fnp-3679	25	21	.	.	PROPN
fnp-3679	25	22	thirty	thirty	NUM
fnp-3679	25	23	-	-	PUNCT
fnp-3679	25	24	three	three	NUM
fnp-3679	25	25	patients	patient	NOUN
fnp-3679	25	26	had	have	VERB
fnp-3679	25	27	homozygous	homozygous	ADJ
fnp-3679	25	28	guanine	guanine	NOUN
fnp-3679	25	29	-	-	PUNCT
fnp-3679	25	30	adenine	adenine	NOUN
fnp-3679	25	31	-	-	PUNCT
fnp-3679	25	32	adenine	adenine	NOUN
fnp-3679	25	33	(	(	PUNCT
fnp-3679	25	34	gaa	gaa	NOUN
fnp-3679	25	35	)	)	PUNCT
fnp-3679	25	36	trinucleotide	trinucleotide	NOUN
fnp-3679	25	37	repeat	repeat	NOUN
fnp-3679	25	38	expansions	expansion	NOUN
fnp-3679	25	39	,	,	PUNCT
fnp-3679	25	40	and	and	CCONJ
fnp-3679	25	41	two	two	NUM
fnp-3679	25	42	were	be	AUX
fnp-3679	25	43	compound	compound	ADJ
fnp-3679	25	44	heterozygotes	heterozygote	NOUN
fnp-3679	25	45	(	(	PUNCT
fnp-3679	25	46	becker	becker	PROPN
fnp-3679	25	47	et	et	PROPN
fnp-3679	25	48	al	al	PROPN
fnp-3679	25	49	.	.	PROPN
fnp-3679	25	50	,	,	PUNCT
fnp-3679	25	51	2017	2017	NUM
fnp-3679	25	52	)	)	PUNCT
fnp-3679	25	53	.	.	PUNCT
fnp-3679	26	1	thirty	thirty	NUM
fnp-3679	26	2	-	-	PUNCT
fnp-3679	26	3	four	four	NUM
fnp-3679	26	4	patients	patient	NOUN
fnp-3679	26	5	had	have	VERB
fnp-3679	26	6	clinical	clinical	ADJ
fnp-3679	26	7	heart	heart	NOUN
fnp-3679	26	8	disease	disease	NOUN
fnp-3679	26	9	or	or	CCONJ
fnp-3679	26	10	fa	fa	X
fnp-3679	26	11	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	26	12	by	by	ADP
fnp-3679	26	13	histology	histology	NOUN
fnp-3679	26	14	.	.	PUNCT
fnp-3679	27	1	one	one	NUM
fnp-3679	27	2	fa	fa	NOUN
fnp-3679	27	3	patient	patient	NOUN
fnp-3679	27	4	had	have	VERB
fnp-3679	27	5	no	no	DET
fnp-3679	27	6	heart	heart	NOUN
fnp-3679	27	7	disease	disease	NOUN
fnp-3679	27	8	during	during	ADP
fnp-3679	27	9	life	life	NOUN
fnp-3679	27	10	or	or	CCONJ
fnp-3679	27	11	under	under	ADP
fnp-3679	27	12	the	the	DET
fnp-3679	27	13	microscope	microscope	NOUN
fnp-3679	27	14	.	.	PUNCT
fnp-3679	28	1	normal	normal	ADJ
fnp-3679	28	2	hearts	heart	NOUN
fnp-3679	28	3	were	be	AUX
fnp-3679	28	4	made	make	VERB
fnp-3679	28	5	available	available	ADJ
fnp-3679	28	6	by	by	ADP
fnp-3679	28	7	national	national	ADJ
fnp-3679	28	8	disease	disease	PROPN
fnp-3679	28	9	research	research	NOUN
fnp-3679	28	10	interchange	interchange	PROPN
fnp-3679	28	11	(	(	PUNCT
fnp-3679	28	12	philadelphia	philadelphia	PROPN
fnp-3679	28	13	,	,	PUNCT
fnp-3679	28	14	pa	pa	PROPN
fnp-3679	28	15	,	,	PUNCT
fnp-3679	28	16	usa	usa	PROPN
fnp-3679	28	17	)	)	PUNCT
fnp-3679	28	18	.	.	PUNCT
fnp-3679	29	1	at	at	ADP
fnp-3679	29	2	the	the	DET
fnp-3679	29	3	time	time	NOUN
fnp-3679	29	4	of	of	ADP
fnp-3679	29	5	autopsy	autopsy	ADJ
fnp-3679	29	6	,	,	PUNCT
fnp-3679	29	7	a	a	DET
fnp-3679	29	8	transverse	transverse	NOUN
fnp-3679	29	9	slice	slice	NOUN
fnp-3679	29	10	weighing	weigh	VERB
fnp-3679	29	11	approximately	approximately	ADV
fnp-3679	29	12	50	50	NUM
fnp-3679	29	13	g	g	NOUN
fnp-3679	29	14	,	,	PUNCT
fnp-3679	29	15	was	be	AUX
fnp-3679	29	16	made	make	VERB
fnp-3679	29	17	midway	midway	ADV
fnp-3679	29	18	between	between	ADP
fnp-3679	29	19	the	the	DET
fnp-3679	29	20	apex	apex	NOUN
fnp-3679	29	21	and	and	CCONJ
fnp-3679	29	22	atrioventricular	atrioventricular	ADJ
fnp-3679	29	23	groove	groove	NOUN
fnp-3679	29	24	,	,	PUNCT
fnp-3679	29	25	and	and	CCONJ
fnp-3679	29	26	immediately	immediately	ADV
fnp-3679	29	27	frozen	freeze	VERB
fnp-3679	29	28	at	at	ADP
fnp-3679	29	29	-20	-20	NUM
fnp-3679	29	30	°	°	NOUN
fnp-3679	29	31	c	c	NOUN
fnp-3679	29	32	or	or	CCONJ
fnp-3679	29	33	,	,	PUNCT
fnp-3679	29	34	if	if	SCONJ
fnp-3679	29	35	available	available	ADJ
fnp-3679	29	36	,	,	PUNCT
fnp-3679	29	37	at	at	ADP
fnp-3679	29	38	-80	-80	NOUN
fnp-3679	29	39	°	°	NOUN
fnp-3679	29	40	c	c	NOUN
fnp-3679	29	41	.	.	PUNCT
fnp-3679	30	1	the	the	DET
fnp-3679	30	2	remainder	remainder	NOUN
fnp-3679	30	3	of	of	ADP
fnp-3679	30	4	the	the	DET
fnp-3679	30	5	heart	heart	NOUN
fnp-3679	30	6	was	be	AUX
fnp-3679	30	7	fixed	fix	VERB
fnp-3679	30	8	in	in	ADP
fnp-3679	30	9	cold	cold	ADJ
fnp-3679	30	10	phosphate	phosphate	ADJ
fnp-3679	30	11	buffered	buffer	VERB
fnp-3679	30	12	formalin	formalin	NOUN
fnp-3679	30	13	(	(	PUNCT
fnp-3679	30	14	ph	ph	NOUN
fnp-3679	30	15	7.4	7.4	NUM
fnp-3679	30	16	)	)	PUNCT
fnp-3679	30	17	.	.	PUNCT
fnp-3679	31	1	samples	sample	NOUN
fnp-3679	31	2	of	of	ADP
fnp-3679	31	3	formalin	formalin	NOUN
fnp-3679	31	4	-	-	PUNCT
fnp-3679	31	5	fixed	fix	VERB
fnp-3679	31	6	left	left	ADJ
fnp-3679	31	7	ventricular	ventricular	ADJ
fnp-3679	31	8	wall	wall	NOUN
fnp-3679	31	9	(	(	PUNCT
fnp-3679	31	10	lvw	lvw	PROPN
fnp-3679	31	11	)	)	PUNCT
fnp-3679	31	12	were	be	AUX
fnp-3679	31	13	embedded	embed	VERB
fnp-3679	31	14	in	in	ADP
fnp-3679	31	15	paraffin	paraffin	NOUN
fnp-3679	31	16	and	and	CCONJ
fnp-3679	31	17	sectioned	section	VERB
fnp-3679	31	18	at	at	ADP
fnp-3679	31	19	6	6	NUM
fnp-3679	31	20	µm	µm	NOUN
fnp-3679	31	21	for	for	ADP
fnp-3679	31	22	routine	routine	ADJ
fnp-3679	31	23	stains	stain	NOUN
fnp-3679	31	24	,	,	PUNCT
fnp-3679	31	25	immunohistochemistry	immunohistochemistry	NOUN
fnp-3679	31	26	,	,	PUNCT
fnp-3679	31	27	laser	laser	NOUN
fnp-3679	31	28	scanning	scan	VERB
fnp-3679	31	29	confocal	confocal	ADJ
fnp-3679	31	30	congo	congo	NOUN
fnp-3679	31	31	red	red	ADJ
fnp-3679	31	32	fluorescence	fluorescence	NOUN
fnp-3679	31	33	microscopy	microscopy	PROPN
fnp-3679	31	34	,	,	PUNCT
fnp-3679	31	35	and	and	CCONJ
fnp-3679	31	36	double	double	ADJ
fnp-3679	31	37	-	-	PUNCT
fnp-3679	31	38	label	label	NOUN
fnp-3679	31	39	immunofluorescence	immunofluorescence	NOUN
fnp-3679	31	40	with	with	ADP
fnp-3679	31	41	antibodies	antibody	NOUN
fnp-3679	31	42	to	to	PART
fnp-3679	31	43	desmin	desmin	VERB
fnp-3679	31	44	and	and	CCONJ
fnp-3679	31	45	αb	αb	NOUN
fnp-3679	31	46	-	-	PUNCT
fnp-3679	31	47	crystallin	crystallin	NOUN
fnp-3679	31	48	,	,	PUNCT
fnp-3679	31	49	or	or	CCONJ
fnp-3679	31	50	desmin	desmin	VERB
fnp-3679	31	51	and	and	CCONJ
fnp-3679	31	52	atp	atp	PROPN
fnp-3679	31	53	synthase	synthase	NOUN
fnp-3679	31	54	f1	f1	NOUN
fnp-3679	31	55	subunit	subunit	NOUN
fnp-3679	31	56	β	β	X
fnp-3679	31	57	(	(	PUNCT
fnp-3679	31	58	atp5b	atp5b	PROPN
fnp-3679	31	59	)	)	PUNCT
fnp-3679	31	60	,	,	PUNCT
fnp-3679	31	61	a	a	DET
fnp-3679	31	62	mitochondrial	mitochondrial	ADJ
fnp-3679	31	63	marker	marker	NOUN
fnp-3679	31	64	.	.	PUNCT
fnp-3679	32	1	antibody	antibody	NOUN
fnp-3679	32	2	microarray	microarray	NOUN
fnp-3679	32	3	:	:	PUNCT
fnp-3679	32	4	the	the	DET
fnp-3679	32	5	principles	principle	NOUN
fnp-3679	32	6	of	of	ADP
fnp-3679	32	7	this	this	DET
fnp-3679	32	8	proteomic	proteomic	ADJ
fnp-3679	32	9	method	method	NOUN
fnp-3679	32	10	,	,	PUNCT
fnp-3679	32	11	advantages	advantage	NOUN
fnp-3679	32	12	,	,	PUNCT
fnp-3679	32	13	and	and	CCONJ
fnp-3679	32	14	pitfalls	pitfall	NOUN
fnp-3679	32	15	were	be	AUX
fnp-3679	32	16	described	describe	VERB
fnp-3679	32	17	previously	previously	ADV
fnp-3679	32	18	in	in	ADP
fnp-3679	32	19	detail	detail	NOUN
fnp-3679	32	20	(	(	PUNCT
fnp-3679	32	21	yue	yue	PROPN
fnp-3679	32	22	and	and	CCONJ
fnp-3679	32	23	pelech	pelech	NOUN
fnp-3679	32	24	,	,	PUNCT
fnp-3679	32	25	2018	2018	NUM
fnp-3679	32	26	)	)	PUNCT
fnp-3679	32	27	.	.	PUNCT
fnp-3679	33	1	tissue	tissue	NOUN
fnp-3679	33	2	samples	sample	NOUN
fnp-3679	33	3	were	be	AUX
fnp-3679	33	4	homogenized	homogenize	VERB
fnp-3679	33	5	by	by	ADP
fnp-3679	33	6	sonication	sonication	NOUN
fnp-3679	33	7	at	at	ADP
fnp-3679	33	8	ice	ice	NOUN
fnp-3679	33	9	temperatures	temperature	NOUN
fnp-3679	33	10	in	in	ADP
fnp-3679	33	11	a	a	DET
fnp-3679	33	12	lysis	lysis	NOUN
fnp-3679	33	13	buffer	buffer	NOUN
fnp-3679	33	14	containing	contain	VERB
fnp-3679	33	15	(	(	PUNCT
fnp-3679	33	16	concentrations	concentration	NOUN
fnp-3679	33	17	in	in	ADP
fnp-3679	33	18	parentheses	parenthesis	NOUN
fnp-3679	33	19	)	)	PUNCT
fnp-3679	33	20	3	3	NUM
fnp-3679	33	21	-	-	PUNCT
fnp-3679	33	22	morpholinopropane-1	morpholinopropane-1	NUM
fnp-3679	33	23	-	-	ADJ
fnp-3679	33	24	sulfonic	sulfonic	ADJ
fnp-3679	33	25	acid	acid	NOUN
fnp-3679	33	26	buffer	buffer	NOUN
fnp-3679	33	27	ph	ph	VERB
fnp-3679	33	28	7.2	7.2	NUM
fnp-3679	33	29	(	(	PUNCT
fnp-3679	33	30	20	20	NUM
fnp-3679	33	31	mm	mm	NOUN
fnp-3679	33	32	)	)	PUNCT
fnp-3679	33	33	,	,	PUNCT
fnp-3679	33	34	ethylene	ethylene	NOUN
fnp-3679	33	35	glycol	glycol	NOUN
fnp-3679	33	36	-	-	PUNCT
fnp-3679	33	37	bis	bis	NOUN
fnp-3679	33	38	(	(	PUNCT
fnp-3679	33	39	β	β	NOUN
fnp-3679	33	40	-	-	ADJ
fnp-3679	33	41	aminoethyl	aminoethyl	ADJ
fnp-3679	33	42	ether	ether	NOUN
fnp-3679	33	43	)	)	PUNCT
fnp-3679	33	44	,	,	PUNCT
fnp-3679	33	45	n	n	CCONJ
fnp-3679	33	46	,	,	PUNCT
fnp-3679	33	47	n	n	CCONJ
fnp-3679	33	48	,	,	PUNCT
fnp-3679	33	49	n’,n’-tetra	n’,n’-tetra	ADJ
fnp-3679	33	50	acetic	acetic	ADJ
fnp-3679	33	51	acid	acid	NOUN
fnp-3679	33	52	(	(	PUNCT
fnp-3679	33	53	2	2	NUM
fnp-3679	33	54	mm	mm	NOUN
fnp-3679	33	55	)	)	PUNCT
fnp-3679	33	56	,	,	PUNCT
fnp-3679	33	57	ethylenediaminetetraacetic	ethylenediaminetetraacetic	ADJ
fnp-3679	33	58	acid	acid	NOUN
fnp-3679	33	59	(	(	PUNCT
fnp-3679	33	60	2	2	NUM
fnp-3679	33	61	mm	mm	NOUN
fnp-3679	33	62	)	)	PUNCT
fnp-3679	33	63	,	,	PUNCT
fnp-3679	33	64	sodium	sodium	NOUN
fnp-3679	33	65	fluoride	fluoride	NOUN
fnp-3679	33	66	(	(	PUNCT
fnp-3679	33	67	50	50	NUM
fnp-3679	33	68	mm	mm	NOUN
fnp-3679	33	69	)	)	PUNCT
fnp-3679	33	70	,	,	PUNCT
fnp-3679	33	71	β	β	X
fnp-3679	33	72	-	-	NOUN
fnp-3679	33	73	glycerophosphate	glycerophosphate	NOUN
fnp-3679	33	74	(	(	PUNCT
fnp-3679	33	75	60	60	NUM
fnp-3679	33	76	mm	mm	NOUN
fnp-3679	33	77	)	)	PUNCT
fnp-3679	33	78	,	,	PUNCT
fnp-3679	33	79	sodium	sodium	NOUN
fnp-3679	33	80	pyrophosphate	pyrophosphate	NOUN
fnp-3679	33	81	(	(	PUNCT
fnp-3679	33	82	25	25	NUM
fnp-3679	33	83	mm	mm	NOUN
fnp-3679	33	84	)	)	PUNCT
fnp-3679	33	85	,	,	PUNCT
fnp-3679	33	86	sodium	sodium	NOUN
fnp-3679	33	87	orthovanadate	orthovanadate	NOUN
fnp-3679	33	88	(	(	PUNCT
fnp-3679	33	89	5	5	NUM
fnp-3679	33	90	mm	mm	NOUN
fnp-3679	33	91	)	)	PUNCT
fnp-3679	33	92	,	,	PUNCT
fnp-3679	33	93	phenyl	phenyl	NOUN
fnp-3679	33	94	arsine	arsine	NOUN
fnp-3679	33	95	phosphate	phosphate	NOUN
fnp-3679	33	96	(	(	PUNCT
fnp-3679	33	97	50	50	NUM
fnp-3679	33	98	nm	nm	NOUN
fnp-3679	33	99	)	)	PUNCT
fnp-3679	33	100	,	,	PUNCT
fnp-3679	33	101	triton	triton	PROPN
fnp-3679	33	102	x-100	x-100	PROPN
fnp-3679	34	1	(	(	PUNCT
fnp-3679	34	2	1	1	NUM
fnp-3679	34	3	%	%	NOUN
fnp-3679	34	4	)	)	PUNCT
fnp-3679	34	5	,	,	PUNCT
fnp-3679	34	6	and	and	CCONJ
fnp-3679	34	7	sodium	sodium	NOUN
fnp-3679	34	8	dodecylsulfate	dodecylsulfate	VERB
fnp-3679	34	9	(	(	PUNCT
fnp-3679	34	10	0.05	0.05	NUM
fnp-3679	34	11	%	%	NOUN
fnp-3679	34	12	)	)	PUNCT
fnp-3679	34	13	.	.	PUNCT
fnp-3679	35	1	the	the	DET
fnp-3679	35	2	lysis	lysis	NOUN
fnp-3679	35	3	buffer	buffer	NOUN
fnp-3679	35	4	also	also	ADV
fnp-3679	35	5	contained	contain	VERB
fnp-3679	35	6	a	a	DET
fnp-3679	35	7	protease	protease	NOUN
fnp-3679	35	8	inhibitor	inhibitor	NOUN
fnp-3679	35	9	cocktail	cocktail	NOUN
fnp-3679	35	10	of	of	ADP
fnp-3679	35	11	aprotinin	aprotinin	NOUN
fnp-3679	35	12	(	(	PUNCT
fnp-3679	35	13	0.5	0.5	NUM
fnp-3679	35	14	µm	µm	NOUN
fnp-3679	35	15	)	)	PUNCT
fnp-3679	35	16	,	,	PUNCT
fnp-3679	35	17	benzamidine	benzamidine	NOUN
fnp-3679	35	18	(	(	PUNCT
fnp-3679	35	19	3	3	NUM
fnp-3679	35	20	mm	mm	NOUN
fnp-3679	35	21	)	)	PUNCT
fnp-3679	35	22	,	,	PUNCT
fnp-3679	35	23	4(2	4(2	PROPN
fnp-3679	35	24	-	-	PUNCT
fnp-3679	35	25	aminoethyl	aminoethyl	NOUN
fnp-3679	35	26	)	)	PUNCT
fnp-3679	35	27	benzene	benzene	NOUN
fnp-3679	35	28	sulfonyl	sulfonyl	NOUN
fnp-3679	35	29	fluoride	fluoride	PROPN
fnp-3679	35	30	hydrochloric	hydrochloric	ADJ
fnp-3679	35	31	acid	acid	NOUN
fnp-3679	35	32	(	(	PUNCT
fnp-3679	35	33	1	1	NUM
fnp-3679	35	34	mm	mm	NOUN
fnp-3679	35	35	)	)	PUNCT
fnp-3679	35	36	,	,	PUNCT
fnp-3679	35	37	leupeptin	leupeptin	NOUN
fnp-3679	35	38	(	(	PUNCT
fnp-3679	35	39	10	10	NUM
fnp-3679	35	40	µm	µm	NOUN
fnp-3679	35	41	)	)	PUNCT
fnp-3679	35	42	;	;	PUNCT
fnp-3679	35	43	and	and	CCONJ
fnp-3679	35	44	dithiothreitol	dithiothreitol	NOUN
fnp-3679	35	45	(	(	PUNCT
fnp-3679	35	46	1	1	NUM
fnp-3679	35	47	mm	mm	NOUN
fnp-3679	35	48	)	)	PUNCT
fnp-3679	35	49	to	to	PART
fnp-3679	35	50	disrupt	disrupt	VERB
fnp-3679	35	51	disulfide	disulfide	NOUN
fnp-3679	35	52	bonds	bond	NOUN
fnp-3679	35	53	.	.	PUNCT
fnp-3679	36	1	protein	protein	NOUN
fnp-3679	36	2	concentrations	concentration	NOUN
fnp-3679	36	3	were	be	AUX
fnp-3679	36	4	determined	determine	VERB
fnp-3679	36	5	by	by	ADP
fnp-3679	36	6	bradford	bradford	PROPN
fnp-3679	36	7	’s	’s	PART
fnp-3679	36	8	method	method	NOUN
fnp-3679	36	9	(	(	PUNCT
fnp-3679	36	10	1976	1976	NUM
fnp-3679	36	11	)	)	PUNCT
fnp-3679	36	12	.	.	PUNCT
fnp-3679	37	1	proteins	protein	NOUN
fnp-3679	37	2	were	be	AUX
fnp-3679	37	3	cleaved	cleave	VERB
fnp-3679	37	4	at	at	ADP
fnp-3679	37	5	cysteine	cysteine	NOUN
fnp-3679	37	6	residues	residue	NOUN
fnp-3679	37	7	by	by	ADP
fnp-3679	37	8	the	the	DET
fnp-3679	37	9	addition	addition	NOUN
fnp-3679	37	10	of	of	ADP
fnp-3679	37	11	tris	tris	NOUN
fnp-3679	37	12	(	(	PUNCT
fnp-3679	37	13	2	2	NUM
fnp-3679	37	14	-	-	PUNCT
fnp-3679	37	15	carboxyethyl	carboxyethyl	NOUN
fnp-3679	37	16	)	)	PUNCT
fnp-3679	37	17	phosphine	phosphine	NOUN
fnp-3679	37	18	hydrochloride	hydrochloride	NOUN
fnp-3679	37	19	(	(	PUNCT
fnp-3679	37	20	10	10	NUM
fnp-3679	37	21	mm	mm	NOUN
fnp-3679	37	22	)	)	PUNCT
fnp-3679	37	23	to	to	ADP
fnp-3679	37	24	the	the	DET
fnp-3679	37	25	lysis	lysis	NOUN
fnp-3679	37	26	buffer	buffer	NOUN
fnp-3679	37	27	,	,	PUNCT
fnp-3679	37	28	followed	follow	VERB
fnp-3679	37	29	by	by	ADP
fnp-3679	37	30	2	2	NUM
fnp-3679	37	31	-	-	PUNCT
fnp-3679	37	32	nitro-5	nitro-5	NUM
fnp-3679	37	33	-	-	PUNCT
fnp-3679	37	34	thiocyanatobenzoic	thiocyanatobenzoic	ADJ
fnp-3679	37	35	acid	acid	NOUN
fnp-3679	37	36	(	(	PUNCT
fnp-3679	37	37	100	100	NUM
fnp-3679	37	38	mm	mm	NOUN
fnp-3679	37	39	)	)	PUNCT
fnp-3679	37	40	after	after	ADP
fnp-3679	37	41	sonication	sonication	NOUN
fnp-3679	37	42	.	.	PUNCT
fnp-3679	38	1	pooled	pool	VERB
fnp-3679	38	2	lysates	lysate	NOUN
fnp-3679	38	3	were	be	AUX
fnp-3679	38	4	biotinylated	biotinylate	VERB
fnp-3679	38	5	(	(	PUNCT
fnp-3679	38	6	yue	yue	PROPN
fnp-3679	38	7	et	et	PROPN
fnp-3679	38	8	al	al	PROPN
fnp-3679	38	9	.	.	PROPN
fnp-3679	38	10	,	,	PUNCT
fnp-3679	38	11	2017	2017	NUM
fnp-3679	38	12	)	)	PUNCT
fnp-3679	38	13	and	and	CCONJ
fnp-3679	38	14	layered	layer	VERB
fnp-3679	38	15	over	over	ADP
fnp-3679	38	16	2	2	NUM
fnp-3679	38	17	microarrays	microarray	NOUN
fnp-3679	38	18	displaying	display	VERB
fnp-3679	38	19	,	,	PUNCT
fnp-3679	38	20	respectively	respectively	ADV
fnp-3679	38	21	,	,	PUNCT
fnp-3679	38	22	900	900	NUM
fnp-3679	38	23	and	and	CCONJ
fnp-3679	38	24	1150	1150	NUM
fnp-3679	38	25	antibodies	antibody	NOUN
fnp-3679	38	26	to	to	ADP
fnp-3679	38	27	a	a	DET
fnp-3679	38	28	total	total	NOUN
fnp-3679	38	29	of	of	ADP
fnp-3679	38	30	2,050	2,050	NUM
fnp-3679	38	31	antibodies	antibody	NOUN
fnp-3679	38	32	(	(	PUNCT
fnp-3679	38	33	kinexus	kinexus	NOUN
fnp-3679	38	34	bioinformatics	bioinformatics	NOUN
fnp-3679	38	35	,	,	PUNCT
fnp-3679	38	36	vancouver	vancouver	PROPN
fnp-3679	38	37	,	,	PUNCT
fnp-3679	38	38	bc	bc	PROPN
fnp-3679	38	39	,	,	PUNCT
fnp-3679	38	40	canada	canada	PROPN
fnp-3679	38	41	)	)	PUNCT
fnp-3679	38	42	.	.	PUNCT
fnp-3679	39	1	proteins	protein	NOUN
fnp-3679	39	2	bound	bind	VERB
fnp-3679	39	3	to	to	ADP
fnp-3679	39	4	the	the	DET
fnp-3679	39	5	antibody	antibody	NOUN
fnp-3679	39	6	spots	spot	NOUN
fnp-3679	39	7	were	be	AUX
fnp-3679	39	8	detected	detect	VERB
fnp-3679	39	9	by	by	ADP
fnp-3679	39	10	incubation	incubation	NOUN
fnp-3679	39	11	with	with	ADP
fnp-3679	39	12	a	a	DET
fnp-3679	39	13	1:1	1:1	NUM
fnp-3679	39	14	mixture	mixture	NOUN
fnp-3679	39	15	of	of	ADP
fnp-3679	39	16	cy3and	cy3and	PROPN
fnp-3679	39	17	alexa	alexa	PROPN
fnp-3679	39	18	546	546	NUM
fnp-3679	39	19	-	-	PUNCT
fnp-3679	39	20	labeled	label	VERB
fnp-3679	39	21	anti	anti	NOUN
fnp-3679	39	22	-	-	NOUN
fnp-3679	39	23	biotin	biotin	NOUN
fnp-3679	39	24	.	.	PUNCT
fnp-3679	40	1	the	the	DET
fnp-3679	40	2	fluorescent	fluorescent	NOUN
fnp-3679	40	3	signals	signal	NOUN
fnp-3679	40	4	from	from	ADP
fnp-3679	40	5	the	the	DET
fnp-3679	40	6	scanned	scan	VERB
fnp-3679	40	7	microarrays	microarray	NOUN
fnp-3679	40	8	were	be	AUX
fnp-3679	40	9	captured	capture	VERB
fnp-3679	40	10	in	in	ADP
fnp-3679	40	11	a	a	DET
fnp-3679	40	12	tif	tif	PROPN
fnp-3679	40	13	file	file	NOUN
fnp-3679	40	14	image	image	NOUN
fnp-3679	40	15	.	.	PUNCT
fnp-3679	41	1	signals	signal	NOUN
fnp-3679	41	2	were	be	AUX
fnp-3679	41	3	then	then	ADV
fnp-3679	41	4	quantified	quantify	VERB
fnp-3679	41	5	with	with	ADP
fnp-3679	41	6	imagene	imagene	NOUN
fnp-3679	41	7	9.0	9.0	NUM
fnp-3679	41	8	microarray	microarray	NOUN
fnp-3679	41	9	image	image	NOUN
fnp-3679	41	10	analysis	analysis	NOUN
fnp-3679	41	11	software	software	NOUN
fnp-3679	41	12	(	(	PUNCT
fnp-3679	41	13	biodiscovery	biodiscovery	NOUN
fnp-3679	41	14	,	,	PUNCT
fnp-3679	41	15	el	el	PROPN
fnp-3679	41	16	segundo	segundo	NOUN
fnp-3679	41	17	,	,	PUNCT
fnp-3679	41	18	ca	ca	PROPN
fnp-3679	41	19	,	,	PUNCT
fnp-3679	41	20	usa	usa	PROPN
fnp-3679	41	21	)	)	PUNCT
fnp-3679	41	22	and	and	CCONJ
fnp-3679	41	23	normalized	normalize	VERB
fnp-3679	41	24	according	accord	VERB
fnp-3679	41	25	to	to	ADP
fnp-3679	41	26	the	the	DET
fnp-3679	41	27	sum	sum	NOUN
fnp-3679	41	28	of	of	ADP
fnp-3679	41	29	all	all	DET
fnp-3679	41	30	the	the	DET
fnp-3679	41	31	recorded	record	VERB
fnp-3679	41	32	signals	signal	NOUN
fnp-3679	41	33	per	per	ADP
fnp-3679	41	34	field	field	NOUN
fnp-3679	41	35	.	.	PUNCT
fnp-3679	42	1	the	the	DET
fnp-3679	42	2	values	value	NOUN
fnp-3679	42	3	for	for	ADP
fnp-3679	42	4	duplicate	duplicate	ADJ
fnp-3679	42	5	measurements	measurement	NOUN
fnp-3679	42	6	were	be	AUX
fnp-3679	42	7	averaged	average	VERB
fnp-3679	42	8	,	,	PUNCT
fnp-3679	42	9	and	and	CCONJ
fnp-3679	42	10	the	the	DET
fnp-3679	42	11	mean	mean	ADJ
fnp-3679	42	12	value	value	NOUN
fnp-3679	42	13	for	for	ADP
fnp-3679	42	14	the	the	DET
fnp-3679	42	15	difference	difference	NOUN
fnp-3679	42	16	in	in	ADP
fnp-3679	42	17	duplicates	duplicate	NOUN
fnp-3679	42	18	from	from	ADP
fnp-3679	42	19	the	the	DET
fnp-3679	42	20	average	average	NOUN
fnp-3679	42	21	was	be	AUX
fnp-3679	42	22	typically	typically	ADV
fnp-3679	42	23	~10	~10	ADJ
fnp-3679	42	24	%	%	NOUN
fnp-3679	42	25	.	.	PUNCT
fnp-3679	43	1	processing	processing	NOUN
fnp-3679	43	2	lysates	lysate	NOUN
fnp-3679	43	3	of	of	ADP
fnp-3679	43	4	fa	fa	NOUN
fnp-3679	43	5	and	and	CCONJ
fnp-3679	43	6	control	control	VERB
fnp-3679	43	7	hearts	heart	NOUN
fnp-3679	43	8	in	in	ADP
fnp-3679	43	9	triplicate	triplicate	NOUN
fnp-3679	43	10	allowed	allow	VERB
fnp-3679	43	11	statistical	statistical	ADJ
fnp-3679	43	12	determination	determination	NOUN
fnp-3679	43	13	of	of	ADP
fnp-3679	43	14	significant	significant	ADJ
fnp-3679	43	15	upor	upor	ADJ
fnp-3679	43	16	down	down	ADP
fnp-3679	43	17	-	-	PUNCT
fnp-3679	43	18	regulation	regulation	NOUN
fnp-3679	43	19	of	of	ADP
fnp-3679	43	20	proteins	protein	NOUN
fnp-3679	43	21	in	in	ADP
fnp-3679	43	22	fa	fa	NOUN
fnp-3679	43	23	by	by	ADP
fnp-3679	43	24	the	the	DET
fnp-3679	43	25	student	student	NOUN
fnp-3679	43	26	t	t	PROPN
fnp-3679	43	27	-	-	PUNCT
fnp-3679	43	28	test	test	NOUN
fnp-3679	43	29	.	.	PUNCT
fnp-3679	44	1	frataxin	frataxin	PROPN
fnp-3679	44	2	assay	assay	VERB
fnp-3679	44	3	by	by	ADP
fnp-3679	44	4	enzyme	enzyme	NOUN
fnp-3679	44	5	-	-	PUNCT
fnp-3679	44	6	linked	link	VERB
fnp-3679	44	7	immunosorbent	immunosorbent	NOUN
fnp-3679	44	8	assay	assay	PROPN
fnp-3679	44	9	(	(	PUNCT
fnp-3679	44	10	elisa	elisa	NOUN
fnp-3679	44	11	):	):	PUNCT
fnp-3679	44	12	details	detail	NOUN
fnp-3679	44	13	of	of	ADP
fnp-3679	44	14	frataxin	frataxin	NOUN
fnp-3679	44	15	elisa	elisa	NOUN
fnp-3679	44	16	were	be	AUX
fnp-3679	44	17	published	publish	VERB
fnp-3679	44	18	before	before	ADV
fnp-3679	44	19	(	(	PUNCT
fnp-3679	44	20	koeppen	koeppen	PROPN
fnp-3679	44	21	et	et	PROPN
fnp-3679	44	22	al	al	PROPN
fnp-3679	44	23	.	.	PROPN
fnp-3679	44	24	,	,	PUNCT
fnp-3679	44	25	2015	2015	NUM
fnp-3679	44	26	)	)	PUNCT
fnp-3679	44	27	,	,	PUNCT
fnp-3679	44	28	but	but	CCONJ
fnp-3679	44	29	the	the	DET
fnp-3679	44	30	amplifying	amplifying	ADJ
fnp-3679	44	31	steps	step	NOUN
fnp-3679	44	32	with	with	ADP
fnp-3679	44	33	biotinylated	biotinylate	VERB
fnp-3679	44	34	anti	anti	ADJ
fnp-3679	44	35	-	-	ADJ
fnp-3679	44	36	rabbit	rabbit	ADJ
fnp-3679	44	37	igg	igg	NOUN
fnp-3679	44	38	and	and	CCONJ
fnp-3679	44	39	horse	horse	NOUN
fnp-3679	44	40	radish	radish	ADJ
fnp-3679	44	41	peroxidase	peroxidase	NOUN
fnp-3679	44	42	-	-	PUNCT
fnp-3679	44	43	labeled	label	VERB
fnp-3679	44	44	streptavidin	streptavidin	NOUN
fnp-3679	44	45	were	be	AUX
fnp-3679	44	46	omitted	omit	VERB
fnp-3679	44	47	.	.	PUNCT
fnp-3679	45	1	the	the	DET
fnp-3679	45	2	reason	reason	NOUN
fnp-3679	45	3	for	for	ADP
fnp-3679	45	4	the	the	DET
fnp-3679	45	5	change	change	NOUN
fnp-3679	45	6	was	be	AUX
fnp-3679	45	7	the	the	DET
fnp-3679	45	8	presence	presence	NOUN
fnp-3679	45	9	of	of	ADP
fnp-3679	45	10	biotin	biotin	NOUN
fnp-3679	45	11	in	in	ADP
fnp-3679	45	12	non	non	ADJ
fnp-3679	45	13	-	-	ADJ
fnp-3679	45	14	fat	fat	ADJ
fnp-3679	45	15	dry	dry	ADJ
fnp-3679	45	16	milk	milk	NOUN
fnp-3679	45	17	that	that	PRON
fnp-3679	45	18	was	be	AUX
fnp-3679	45	19	used	use	VERB
fnp-3679	45	20	as	as	ADP
fnp-3679	45	21	a	a	DET
fnp-3679	45	22	suppressor	suppressor	NOUN
fnp-3679	45	23	protein	protein	NOUN
fnp-3679	45	24	.	.	PUNCT
fnp-3679	46	1	briefly	briefly	ADV
fnp-3679	46	2	,	,	PUNCT
fnp-3679	46	3	heart	heart	NOUN
fnp-3679	46	4	lysates	lysate	NOUN
fnp-3679	46	5	obtained	obtain	VERB
fnp-3679	46	6	by	by	ADP
fnp-3679	46	7	the	the	DET
fnp-3679	46	8	method	method	NOUN
fnp-3679	46	9	of	of	ADP
fnp-3679	46	10	condò	condò	PROPN
fnp-3679	46	11	et	et	PROPN
fnp-3679	46	12	al	al	PROPN
fnp-3679	46	13	.	.	PROPN
fnp-3679	47	1	(	(	PUNCT
fnp-3679	47	2	2006	2006	NUM
fnp-3679	47	3	)	)	PUNCT
fnp-3679	47	4	were	be	AUX
fnp-3679	47	5	diluted	dilute	VERB
fnp-3679	47	6	10	10	NUM
fnp-3679	47	7	-	-	ADJ
fnp-3679	47	8	fold	fold	ADJ
fnp-3679	47	9	in	in	ADV
fnp-3679	47	10	phosphate	phosphate	NOUN
fnp-3679	47	11	-	-	PUNCT
fnp-3679	47	12	buffered	buffer	VERB
fnp-3679	47	13	saline	saline	NOUN
fnp-3679	47	14	(	(	PUNCT
fnp-3679	47	15	ph	ph	NOUN
fnp-3679	47	16	7.2	7.2	NUM
fnp-3679	47	17	)	)	PUNCT
fnp-3679	47	18	(	(	PUNCT
fnp-3679	47	19	pbs	pbs	PROPN
fnp-3679	47	20	)	)	PUNCT
fnp-3679	47	21	to	to	PART
fnp-3679	47	22	reduce	reduce	VERB
fnp-3679	47	23	the	the	DET
fnp-3679	47	24	concentration	concentration	NOUN
fnp-3679	47	25	of	of	ADP
fnp-3679	47	26	nonionic	nonionic	ADJ
fnp-3679	47	27	detergents	detergent	NOUN
fnp-3679	47	28	to	to	ADP
fnp-3679	47	29	less	less	ADJ
fnp-3679	47	30	than	than	ADP
fnp-3679	47	31	0.1	0.1	NUM
fnp-3679	47	32	%	%	NOUN
fnp-3679	47	33	.	.	PUNCT
fnp-3679	48	1	the	the	DET
fnp-3679	48	2	diluted	diluted	ADJ
fnp-3679	48	3	lysates	lysate	NOUN
fnp-3679	48	4	were	be	AUX
fnp-3679	48	5	centrifuged	centrifuge	VERB
fnp-3679	48	6	through	through	ADP
fnp-3679	48	7	membrane	membrane	NOUN
fnp-3679	48	8	filter	filter	NOUN
fnp-3679	48	9	units	unit	NOUN
fnp-3679	48	10	with	with	ADP
fnp-3679	48	11	a	a	DET
fnp-3679	48	12	molecular	molecular	ADJ
fnp-3679	48	13	mass	mass	NOUN
fnp-3679	48	14	cutoff	cutoff	NOUN
fnp-3679	48	15	of	of	ADP
fnp-3679	48	16	30	30	NUM
fnp-3679	48	17	kda	kda	NOUN
fnp-3679	48	18	(	(	PUNCT
fnp-3679	48	19	millipore	millipore	PROPN
fnp-3679	48	20	sigma	sigma	PROPN
fnp-3679	48	21	,	,	PUNCT
fnp-3679	48	22	burlington	burlington	PROPN
fnp-3679	48	23	,	,	PUNCT
fnp-3679	48	24	ma	ma	PROPN
fnp-3679	48	25	,	,	PUNCT
fnp-3679	48	26	usa	usa	PROPN
fnp-3679	48	27	)	)	PUNCT
fnp-3679	48	28	.	.	PUNCT
fnp-3679	49	1	wells	well	NOUN
fnp-3679	49	2	of	of	ADP
fnp-3679	49	3	polystyrene	polystyrene	NOUN
fnp-3679	49	4	elisa	elisa	NOUN
fnp-3679	49	5	plates	plate	NOUN
fnp-3679	49	6	were	be	AUX
fnp-3679	49	7	coated	coat	VERB
fnp-3679	49	8	with	with	ADP
fnp-3679	49	9	a	a	DET
fnp-3679	49	10	layer	layer	NOUN
fnp-3679	49	11	of	of	ADP
fnp-3679	49	12	monoclonal	monoclonal	NOUN
fnp-3679	49	13	anti	anti	ADJ
fnp-3679	49	14	-	-	NOUN
fnp-3679	49	15	frataxin	frataxin	ADJ
fnp-3679	49	16	(	(	PUNCT
fnp-3679	49	17	abcam	abcam	PROPN
fnp-3679	49	18	,	,	PUNCT
fnp-3679	49	19	cambridge	cambridge	PROPN
fnp-3679	49	20	,	,	PUNCT
fnp-3679	49	21	ma	ma	PROPN
fnp-3679	49	22	,	,	PUNCT
fnp-3679	49	23	usa	usa	PROPN
fnp-3679	49	24	,	,	PUNCT
fnp-3679	49	25	cat	cat	NOUN
fnp-3679	49	26	.	.	PUNCT
fnp-3679	50	1	no	no	INTJ
fnp-3679	50	2	.	.	PUNCT
fnp-3679	51	1	ab268063	ab268063	PROPN
fnp-3679	51	2	)	)	PUNCT
fnp-3679	51	3	,	,	PUNCT
fnp-3679	51	4	followed	follow	VERB
fnp-3679	51	5	by	by	ADP
fnp-3679	51	6	aliquots	aliquot	NOUN
fnp-3679	51	7	of	of	ADP
fnp-3679	51	8	filtered	filter	VERB
fnp-3679	51	9	lysates	lysate	NOUN
fnp-3679	51	10	(	(	PUNCT
fnp-3679	51	11	corresponding	correspond	VERB
fnp-3679	51	12	to	to	ADP
fnp-3679	51	13	4	4	NUM
fnp-3679	51	14	mg	mg	NOUN
fnp-3679	51	15	original	original	ADJ
fnp-3679	51	16	tissue	tissue	NOUN
fnp-3679	51	17	)	)	PUNCT
fnp-3679	51	18	or	or	CCONJ
fnp-3679	51	19	human	human	ADJ
fnp-3679	51	20	recombinant	recombinant	ADJ
fnp-3679	51	21	frataxin	frataxin	NOUN
fnp-3679	51	22	(	(	PUNCT
fnp-3679	51	23	10	10	NUM
fnp-3679	51	24	pg	pg	NOUN
fnp-3679	51	25	to	to	ADP
fnp-3679	51	26	1	1	NUM
fnp-3679	51	27	ng	ng	PROPN
fnp-3679	51	28	;	;	PUNCT
fnp-3679	51	29	abcam	abcam	PROPN
fnp-3679	51	30	,	,	PUNCT
fnp-3679	51	31	cat	cat	NOUN
fnp-3679	51	32	.	.	PUNCT
fnp-3679	52	1	no	no	INTJ
fnp-3679	52	2	.	.	PUNCT
fnp-3679	52	3	ab95502	ab95502	PROPN
fnp-3679	52	4	)	)	PUNCT
fnp-3679	52	5	.	.	PUNCT
fnp-3679	53	1	the	the	DET
fnp-3679	53	2	sequence	sequence	NOUN
fnp-3679	53	3	of	of	ADP
fnp-3679	53	4	subsequent	subsequent	ADJ
fnp-3679	53	5	additions	addition	NOUN
fnp-3679	53	6	(	(	PUNCT
fnp-3679	53	7	washing	washing	NOUN
fnp-3679	53	8	steps	step	NOUN
fnp-3679	53	9	omitted	omit	VERB
fnp-3679	53	10	)	)	PUNCT
fnp-3679	53	11	was	be	AUX
fnp-3679	53	12	polyclonal	polyclonal	ADJ
fnp-3679	53	13	anti	anti	ADJ
fnp-3679	53	14	-	-	NOUN
fnp-3679	53	15	frataxin	frataxin	ADJ
fnp-3679	53	16	(	(	PUNCT
fnp-3679	53	17	abcam	abcam	PROPN
fnp-3679	53	18	,	,	PUNCT
fnp-3679	53	19	cat	cat	NOUN
fnp-3679	53	20	.	.	PUNCT
fnp-3679	54	1	no	no	INTJ
fnp-3679	54	2	.	.	PUNCT
fnp-3679	54	3	ab175402	ab175402	PROPN
fnp-3679	54	4	)	)	PUNCT
fnp-3679	54	5	and	and	CCONJ
fnp-3679	54	6	horseradish	horseradish	ADJ
fnp-3679	54	7	peroxidase	peroxidase	NOUN
fnp-3679	54	8	-	-	PUNCT
fnp-3679	54	9	labeled	label	VERB
fnp-3679	54	10	goat	goat	PROPN
fnp-3679	54	11	anti	anti	ADJ
fnp-3679	54	12	-	-	ADJ
fnp-3679	54	13	rabbit	rabbit	ADJ
fnp-3679	54	14	gamma	gamma	NOUN
fnp-3679	54	15	globulin	globulin	NOUN
fnp-3679	54	16	(	(	PUNCT
fnp-3679	54	17	sigma	sigma	PROPN
fnp-3679	54	18	,	,	PUNCT
fnp-3679	54	19	st	st	PROPN
fnp-3679	54	20	.	.	PROPN
fnp-3679	54	21	louis	louis	PROPN
fnp-3679	54	22	,	,	PUNCT
fnp-3679	54	23	mo	mo	PROPN
fnp-3679	54	24	,	,	PUNCT
fnp-3679	54	25	usa	usa	PROPN
fnp-3679	54	26	,	,	PUNCT
fnp-3679	54	27	cat	cat	NOUN
fnp-3679	54	28	.	.	PUNCT
fnp-3679	55	1	no	no	INTJ
fnp-3679	55	2	.	.	PUNCT
fnp-3679	56	1	a4914	a4914	PROPN
fnp-3679	56	2	)	)	PUNCT
fnp-3679	56	3	.	.	PUNCT
fnp-3679	57	1	the	the	DET
fnp-3679	57	2	chromogenic	chromogenic	ADJ
fnp-3679	57	3	solution	solution	NOUN
fnp-3679	57	4	contained	contain	VERB
fnp-3679	57	5	ortho	ortho	PROPN
fnp-3679	57	6	-	-	PUNCT
fnp-3679	57	7	phenylenediamine	phenylenediamine	NOUN
fnp-3679	57	8	(	(	PUNCT
fnp-3679	57	9	2	2	NUM
fnp-3679	57	10	mm	mm	NOUN
fnp-3679	57	11	)	)	PUNCT
fnp-3679	57	12	and	and	CCONJ
fnp-3679	57	13	0.01	0.01	NUM
fnp-3679	57	14	%	%	NOUN
fnp-3679	57	15	hydrogen	hydrogen	NOUN
fnp-3679	57	16	peroxide	peroxide	NOUN
fnp-3679	57	17	in	in	ADP
fnp-3679	57	18	sodium	sodium	NOUN
fnp-3679	57	19	phosphate	phosphate	NOUN
fnp-3679	57	20	-	-	PUNCT
fnp-3679	57	21	citric	citric	NOUN
fnp-3679	57	22	acid	acid	NOUN
fnp-3679	57	23	buffer	buffer	NOUN
fnp-3679	57	24	(	(	PUNCT
fnp-3679	57	25	ph	ph	NOUN
fnp-3679	57	26	5	5	NUM
fnp-3679	57	27	)	)	PUNCT
fnp-3679	57	28	.	.	PUNCT
fnp-3679	58	1	absorbances	absorbance	NOUN
fnp-3679	58	2	at	at	ADP
fnp-3679	58	3	492	492	NUM
fnp-3679	58	4	nm	nm	NOUN
fnp-3679	58	5	were	be	AUX
fnp-3679	58	6	determined	determine	VERB
fnp-3679	58	7	in	in	ADP
fnp-3679	58	8	an	an	DET
fnp-3679	58	9	elisa	elisa	NOUN
fnp-3679	58	10	plate	plate	NOUN
fnp-3679	58	11	reader	reader	NOUN
fnp-3679	58	12	manufactured	manufacture	VERB
fnp-3679	58	13	by	by	ADP
fnp-3679	58	14	molecular	molecular	ADJ
fnp-3679	58	15	devices	device	NOUN
fnp-3679	58	16	(	(	PUNCT
fnp-3679	58	17	san	san	PROPN
fnp-3679	58	18	josé	josé	PROPN
fnp-3679	58	19	,	,	PUNCT
fnp-3679	58	20	ca	ca	PROPN
fnp-3679	58	21	,	,	PUNCT
fnp-3679	58	22	usa	usa	PROPN
fnp-3679	58	23	)	)	PUNCT
fnp-3679	58	24	.	.	PUNCT
fnp-3679	59	1	frataxin	frataxin	PROPN
fnp-3679	59	2	levels	level	NOUN
fnp-3679	59	3	were	be	AUX
fnp-3679	59	4	expressed	express	VERB
fnp-3679	59	5	as	as	ADP
fnp-3679	59	6	ng	ng	PROPN
fnp-3679	59	7	/	/	SYM
fnp-3679	59	8	g	g	PROPN
fnp-3679	59	9	wet	wet	ADJ
fnp-3679	59	10	weight	weight	NOUN
fnp-3679	59	11	.	.	PUNCT
fnp-3679	60	1	coimmunoprecipitation	coimmunoprecipitation	NOUN
fnp-3679	60	2	:	:	PUNCT
fnp-3679	60	3	pooled	pool	VERB
fnp-3679	60	4	tissue	tissue	NOUN
fnp-3679	60	5	lysate	lysate	NOUN
fnp-3679	60	6	of	of	ADP
fnp-3679	60	7	6	6	NUM
fnp-3679	60	8	fa	fa	NOUN
fnp-3679	60	9	hearts	heart	NOUN
fnp-3679	60	10	,	,	PUNCT
fnp-3679	60	11	corresponding	correspond	VERB
fnp-3679	60	12	to	to	ADP
fnp-3679	60	13	150	150	NUM
fnp-3679	60	14	mg	mg	ADV
fnp-3679	60	15	wet	wet	ADJ
fnp-3679	60	16	tissue	tissue	NOUN
fnp-3679	60	17	in	in	ADP
fnp-3679	60	18	a	a	DET
fnp-3679	60	19	volume	volume	NOUN
fnp-3679	60	20	of	of	ADP
fnp-3679	60	21	150	150	NUM
fnp-3679	60	22	µl	µl	NOUN
fnp-3679	60	23	,	,	PUNCT
fnp-3679	60	24	were	be	AUX
fnp-3679	60	25	mixed	mix	VERB
fnp-3679	60	26	with	with	ADP
fnp-3679	60	27	5	5	NUM
fnp-3679	60	28	µg	µg	ADV
fnp-3679	60	29	rabbit	rabbit	NOUN
fnp-3679	60	30	polyclonal	polyclonal	ADJ
fnp-3679	60	31	anti	anti	ADJ
fnp-3679	60	32	-	-	ADJ
fnp-3679	60	33	desmin	desmin	ADJ
fnp-3679	60	34	and	and	CCONJ
fnp-3679	60	35	50	50	NUM
fnp-3679	60	36	µl	µl	NOUN
fnp-3679	60	37	of	of	ADP
fnp-3679	60	38	a	a	DET
fnp-3679	60	39	slurry	slurry	NOUN
fnp-3679	60	40	of	of	ADP
fnp-3679	60	41	protein	protein	NOUN
fnp-3679	60	42	a	a	PRON
fnp-3679	60	43	on	on	ADP
fnp-3679	60	44	sepharose	sepharose	NOUN
fnp-3679	60	45	beads	bead	NOUN
fnp-3679	60	46	(	(	PUNCT
fnp-3679	60	47	thermo	thermo	NOUN
fnp-3679	60	48	scientific	scientific	NOUN
fnp-3679	60	49	,	,	PUNCT
fnp-3679	60	50	rockford	rockford	PROPN
fnp-3679	60	51	,	,	PUNCT
fnp-3679	60	52	il	il	PROPN
fnp-3679	60	53	,	,	PUNCT
fnp-3679	60	54	usa	usa	PROPN
fnp-3679	60	55	,	,	PUNCT
fnp-3679	60	56	cat	cat	NOUN
fnp-3679	60	57	.	.	PUNCT
fnp-3679	61	1	no	no	INTJ
fnp-3679	61	2	.	.	NOUN
fnp-3679	62	1	29333	29333	NUM
fnp-3679	62	2	)	)	PUNCT
fnp-3679	62	3	.	.	PUNCT
fnp-3679	63	1	after	after	ADP
fnp-3679	63	2	overnight	overnight	ADJ
fnp-3679	63	3	incubation	incubation	NOUN
fnp-3679	63	4	at	at	ADP
fnp-3679	63	5	4	4	NUM
fnp-3679	63	6	ͦc	ͦc	NUM
fnp-3679	63	7	,	,	PUNCT
fnp-3679	63	8	the	the	DET
fnp-3679	63	9	sepharose	sepharose	NOUN
fnp-3679	63	10	particles	particle	NOUN
fnp-3679	63	11	were	be	AUX
fnp-3679	63	12	collected	collect	VERB
fnp-3679	63	13	by	by	ADP
fnp-3679	63	14	brief	brief	ADJ
fnp-3679	63	15	centrifugation	centrifugation	NOUN
fnp-3679	63	16	and	and	CCONJ
fnp-3679	63	17	washed	wash	VERB
fnp-3679	63	18	with	with	ADP
fnp-3679	63	19	phosphate	phosphate	NOUN
fnp-3679	63	20	-	-	PUNCT
fnp-3679	63	21	buffered	buffer	VERB
fnp-3679	63	22	saline	saline	NOUN
fnp-3679	63	23	(	(	PUNCT
fnp-3679	63	24	pbs	pbs	PROPN
fnp-3679	63	25	)	)	PUNCT
fnp-3679	63	26	.	.	PUNCT
fnp-3679	64	1	bound	bind	VERB
fnp-3679	64	2	proteins	protein	NOUN
fnp-3679	64	3	were	be	AUX
fnp-3679	64	4	released	release	VERB
fnp-3679	64	5	from	from	ADP
fnp-3679	64	6	protein	protein	NOUN
fnp-3679	64	7	a	a	NOUN
fnp-3679	64	8	-	-	PUNCT
fnp-3679	64	9	sepharose	sepharose	NOUN
fnp-3679	64	10	by	by	ADP
fnp-3679	64	11	laemmli	laemmli	NOUN
fnp-3679	64	12	’s	’s	PART
fnp-3679	64	13	sample	sample	NOUN
fnp-3679	64	14	buffer	buffer	NOUN
fnp-3679	64	15	and	and	CCONJ
fnp-3679	64	16	heating	heating	NOUN
fnp-3679	64	17	at	at	ADP
fnp-3679	64	18	100	100	NUM
fnp-3679	64	19	ͦc	ͦc	NUM
fnp-3679	64	20	for	for	ADP
fnp-3679	64	21	15	15	NUM
fnp-3679	64	22	min	min	NOUN
fnp-3679	64	23	.	.	NOUN
fnp-3679	64	24	after	after	ADP
fnp-3679	64	25	cooling	cool	VERB
fnp-3679	64	26	,	,	PUNCT
fnp-3679	64	27	the	the	DET
fnp-3679	64	28	remaining	remain	VERB
fnp-3679	64	29	sepharose	sepharose	NOUN
fnp-3679	64	30	particles	particle	NOUN
fnp-3679	64	31	were	be	AUX
fnp-3679	64	32	precipitated	precipitate	VERB
fnp-3679	64	33	by	by	ADP
fnp-3679	64	34	brief	brief	ADJ
fnp-3679	64	35	centrifugation	centrifugation	NOUN
fnp-3679	64	36	,	,	PUNCT
fnp-3679	64	37	and	and	CCONJ
fnp-3679	64	38	24	24	NUM
fnp-3679	64	39	µl	µl	ADP
fnp-3679	64	40	aliquots	aliquot	NOUN
fnp-3679	64	41	were	be	AUX
fnp-3679	64	42	electrophoresed	electrophorese	VERB
fnp-3679	64	43	on	on	ADP
fnp-3679	64	44	10	10	NUM
fnp-3679	64	45	%	%	NOUN
fnp-3679	64	46	polyacrylamide	polyacrylamide	NOUN
fnp-3679	64	47	gels	gel	NOUN
fnp-3679	64	48	.	.	PUNCT
fnp-3679	65	1	at	at	ADP
fnp-3679	65	2	the	the	DET
fnp-3679	65	3	end	end	NOUN
fnp-3679	65	4	of	of	ADP
fnp-3679	65	5	the	the	DET
fnp-3679	65	6	electrophoresis	electrophoresis	NOUN
fnp-3679	65	7	,	,	PUNCT
fnp-3679	65	8	proteins	protein	NOUN
fnp-3679	65	9	were	be	AUX
fnp-3679	65	10	transferred	transfer	VERB
fnp-3679	65	11	by	by	ADP
fnp-3679	65	12	electroblotting	electroblotte	VERB
fnp-3679	65	13	onto	onto	ADP
fnp-3679	65	14	polyvinyledenefluoride	polyvinyledenefluoride	NOUN
fnp-3679	65	15	(	(	PUNCT
fnp-3679	65	16	pvdf	pvdf	NOUN
fnp-3679	65	17	)	)	PUNCT
fnp-3679	65	18	membranes	membrane	NOUN
fnp-3679	65	19	.	.	PUNCT
fnp-3679	66	1	the	the	DET
fnp-3679	66	2	pvdf	pvdf	PROPN
fnp-3679	66	3	membranes	membrane	NOUN
fnp-3679	66	4	were	be	AUX
fnp-3679	66	5	cut	cut	VERB
fnp-3679	66	6	into	into	ADP
fnp-3679	66	7	longitudinal	longitudinal	ADJ
fnp-3679	66	8	strips	strip	NOUN
fnp-3679	66	9	for	for	ADP
fnp-3679	66	10	the	the	DET
fnp-3679	66	11	detection	detection	NOUN
fnp-3679	66	12	of	of	ADP
fnp-3679	66	13	established	established	ADJ
fnp-3679	66	14	or	or	CCONJ
fnp-3679	66	15	putative	putative	ADJ
fnp-3679	66	16	desmin	desmin	ADJ
fnp-3679	66	17	-	-	PUNCT
fnp-3679	66	18	associated	associate	VERB
fnp-3679	66	19	proteins	protein	NOUN
fnp-3679	66	20	(	(	PUNCT
fnp-3679	66	21	frataxin	frataxin	NOUN
fnp-3679	66	22	,	,	PUNCT
fnp-3679	66	23	αb	αb	NOUN
fnp-3679	66	24	-	-	NOUN
fnp-3679	66	25	crystallin	crystallin	NOUN
fnp-3679	66	26	;	;	PUNCT
fnp-3679	66	27	α	α	X
fnp-3679	66	28	-	-	NOUN
fnp-3679	66	29	actinin	actinin	NOUN
fnp-3679	66	30	,	,	PUNCT
fnp-3679	66	31	ankyrin	ankyrin	NOUN
fnp-3679	66	32	1	1	NUM
fnp-3679	66	33	,	,	PUNCT
fnp-3679	66	34	α	α	NOUN
fnp-3679	66	35	-	-	PUNCT
fnp-3679	66	36	spectrin	spectrin	NOUN
fnp-3679	66	37	,	,	PUNCT
fnp-3679	66	38	plectin	plectin	NOUN
fnp-3679	66	39	,	,	PUNCT
fnp-3679	66	40	and	and	CCONJ
fnp-3679	66	41	zasp	zasp	NOUN
fnp-3679	67	1	[	[	X
fnp-3679	67	2	cypher	cypher	X
fnp-3679	67	3	]	]	X
fnp-3679	67	4	)	)	PUNCT
fnp-3679	67	5	.	.	PUNCT
fnp-3679	68	1	sources	source	NOUN
fnp-3679	68	2	of	of	ADP
fnp-3679	68	3	antibodies	antibody	NOUN
fnp-3679	68	4	were	be	AUX
fnp-3679	68	5	as	as	SCONJ
fnp-3679	68	6	follows	follow	VERB
fnp-3679	68	7	:	:	PUNCT
fnp-3679	68	8	anti	anti	ADJ
fnp-3679	68	9	-	-	ADJ
fnp-3679	68	10	desmin	desmin	ADJ
fnp-3679	68	11	(	(	PUNCT
fnp-3679	68	12	polyclonal	polyclonal	ADJ
fnp-3679	68	13	,	,	PUNCT
fnp-3679	68	14	invitrogen	invitrogen	PROPN
fnp-3679	68	15	,	,	PUNCT
fnp-3679	68	16	rockford	rockford	PROPN
fnp-3679	68	17	,	,	PUNCT
fnp-3679	68	18	il	il	PROPN
fnp-3679	68	19	,	,	PUNCT
fnp-3679	68	20	usa	usa	PROPN
fnp-3679	68	21	.	.	PROPN
fnp-3679	68	22	cat	cat	PROPN
fnp-3679	69	1	no	no	INTJ
fnp-3679	69	2	.	.	PUNCT
fnp-3679	70	1	pa5	pa5	ADJ
fnp-3679	70	2	-	-	PUNCT
fnp-3679	70	3	16705	16705	NUM
fnp-3679	70	4	)	)	PUNCT
fnp-3679	70	5	;	;	PUNCT
fnp-3679	70	6	anti	anti	ADJ
fnp-3679	70	7	-	-	ADJ
fnp-3679	70	8	αb	αb	NOUN
fnp-3679	70	9	-	-	PUNCT
fnp-3679	70	10	crystallin	crystallin	NOUN
fnp-3679	70	11	(	(	PUNCT
fnp-3679	70	12	monoclonal	monoclonal	NOUN
fnp-3679	70	13	,	,	PUNCT
fnp-3679	70	14	santa	santa	PROPN
fnp-3679	70	15	cruz	cruz	PROPN
fnp-3679	70	16	biotechnology	biotechnology	PROPN
fnp-3679	70	17	,	,	PUNCT
fnp-3679	70	18	dallas	dallas	PROPN
fnp-3679	70	19	,	,	PUNCT
fnp-3679	70	20	tx	tx	PROPN
fnp-3679	70	21	,	,	PUNCT
fnp-3679	70	22	usa	usa	PROPN
fnp-3679	70	23	.	.	PROPN
fnp-3679	70	24	cat	cat	PROPN
fnp-3679	70	25	.	.	PUNCT
fnp-3679	71	1	no	no	INTJ
fnp-3679	71	2	.	.	PUNCT
fnp-3679	72	1	sc-137129	sc-137129	PROPN
fnp-3679	72	2	)	)	PUNCT
fnp-3679	73	1	;	;	PUNCT
fnp-3679	73	2	anti	anti	ADJ
fnp-3679	73	3	-	-	ADJ
fnp-3679	73	4	α	α	ADJ
fnp-3679	73	5	-	-	ADJ
fnp-3679	73	6	actinin	actinin	ADJ
fnp-3679	73	7	(	(	PUNCT
fnp-3679	73	8	monoclonal	monoclonal	NOUN
fnp-3679	73	9	,	,	PUNCT
fnp-3679	73	10	abcam	abcam	PROPN
fnp-3679	73	11	,	,	PUNCT
fnp-3679	73	12	waltham	waltham	PROPN
fnp-3679	73	13	,	,	PUNCT
fnp-3679	73	14	ma	ma	PROPN
fnp-3679	73	15	,	,	PUNCT
fnp-3679	73	16	usa	usa	PROPN
fnp-3679	73	17	,	,	PUNCT
fnp-3679	73	18	cat	cat	NOUN
fnp-3679	73	19	.	.	PUNCT
fnp-3679	74	1	no	no	INTJ
fnp-3679	74	2	.	.	PUNCT
fnp-3679	75	1	ab62298	ab62298	PROPN
fnp-3679	75	2	)	)	PUNCT
fnp-3679	75	3	;	;	PUNCT
fnp-3679	75	4	anti	anti	ADJ
fnp-3679	75	5	-	-	ADJ
fnp-3679	75	6	ankyrin	ankyrin	ADJ
fnp-3679	75	7	1	1	NUM
fnp-3679	75	8	(	(	PUNCT
fnp-3679	75	9	monoclonal	monoclonal	NOUN
fnp-3679	75	10	,	,	PUNCT
fnp-3679	75	11	santa	santa	PROPN
fnp-3679	75	12	cruz	cruz	PROPN
fnp-3679	75	13	biotechnology	biotechnology	PROPN
fnp-3679	75	14	,	,	PUNCT
fnp-3679	75	15	cat	cat	NOUN
fnp-3679	75	16	.	.	PUNCT
fnp-3679	76	1	no	no	INTJ
fnp-3679	76	2	.	.	PUNCT
fnp-3679	77	1	sc-12719	sc-12719	PROPN
fnp-3679	77	2	)	)	PUNCT
fnp-3679	77	3	;	;	PUNCT
fnp-3679	77	4	anti	anti	ADJ
fnp-3679	77	5	-	-	ADJ
fnp-3679	77	6	α	α	NOUN
fnp-3679	77	7	-	-	PUNCT
fnp-3679	77	8	spectrin	spectrin	NOUN
fnp-3679	77	9	(	(	PUNCT
fnp-3679	77	10	monoclonal	monoclonal	NOUN
fnp-3679	77	11	,	,	PUNCT
fnp-3679	77	12	santa	santa	PROPN
fnp-3679	77	13	cruz	cruz	PROPN
fnp-3679	77	14	,	,	PUNCT
fnp-3679	77	15	cat	cat	NOUN
fnp-3679	78	1	no	no	INTJ
fnp-3679	78	2	.	.	PUNCT
fnp-3679	78	3	sc-48382	sc-48382	PROPN
fnp-3679	78	4	)	)	PUNCT
fnp-3679	78	5	;	;	PUNCT
fnp-3679	78	6	anti	anti	ADJ
fnp-3679	78	7	-	-	ADJ
fnp-3679	78	8	plectin	plectin	ADJ
fnp-3679	78	9	(	(	PUNCT
fnp-3679	78	10	monoclonal	monoclonal	NOUN
fnp-3679	78	11	,	,	PUNCT
fnp-3679	78	12	santa	santa	PROPN
fnp-3679	78	13	cruz	cruz	PROPN
fnp-3679	78	14	biotechnology	biotechnology	PROPN
fnp-3679	78	15	,	,	PUNCT
fnp-3679	78	16	cat	cat	NOUN
fnp-3679	78	17	.	.	PUNCT
fnp-3679	79	1	no	no	INTJ
fnp-3679	79	2	.	.	NOUN
fnp-3679	79	3	37649	37649	NUM
fnp-3679	79	4	)	)	PUNCT
fnp-3679	79	5	;	;	PUNCT
fnp-3679	80	1	anti	anti	ADJ
fnp-3679	80	2	-	-	ADJ
fnp-3679	80	3	zasp	zasp	ADJ
fnp-3679	80	4	(	(	PUNCT
fnp-3679	80	5	cypher	cypher	PROPN
fnp-3679	80	6	)	)	PUNCT
fnp-3679	80	7	(	(	PUNCT
fnp-3679	80	8	monoclonal	monoclonal	NOUN
fnp-3679	80	9	,	,	PUNCT
fnp-3679	80	10	santa	santa	PROPN
fnp-3679	80	11	cruz	cruz	PROPN
fnp-3679	80	12	biotechnology	biotechnology	PROPN
fnp-3679	80	13	,	,	PUNCT
fnp-3679	80	14	cat	cat	NOUN
fnp-3679	80	15	.	.	PUNCT
fnp-3679	81	1	no	no	INTJ
fnp-3679	81	2	.	.	PUNCT
fnp-3679	81	3	sc-374359	sc-374359	ADJ
fnp-3679	81	4	)	)	PUNCT
fnp-3679	81	5	;	;	PUNCT
fnp-3679	81	6	and	and	CCONJ
fnp-3679	81	7	anti	anti	ADJ
fnp-3679	81	8	-	-	ADJ
fnp-3679	81	9	frataxin	frataxin	ADJ
fnp-3679	81	10	(	(	PUNCT
fnp-3679	81	11	monoclonal	monoclonal	NOUN
fnp-3679	81	12	,	,	PUNCT
fnp-3679	81	13	abcam	abcam	PROPN
fnp-3679	81	14	,	,	PUNCT
fnp-3679	81	15	branford	branford	PROPN
fnp-3679	81	16	,	,	PUNCT
fnp-3679	81	17	ct	ct	PROPN
fnp-3679	81	18	,	,	PUNCT
fnp-3679	81	19	usa	usa	PROPN
fnp-3679	81	20	;	;	PUNCT
fnp-3679	81	21	cat	cat	NOUN
fnp-3679	81	22	.	.	PUNCT
fnp-3679	82	1	no	no	INTJ
fnp-3679	82	2	.	.	PUNCT
fnp-3679	83	1	ab268063	ab268063	PROPN
fnp-3679	83	2	)	)	PUNCT
fnp-3679	83	3	.	.	PUNCT
fnp-3679	84	1	mass	mass	PROPN
fnp-3679	84	2	spectrometry	spectrometry	NOUN
fnp-3679	84	3	:	:	PUNCT
fnp-3679	84	4	protein	protein	NOUN
fnp-3679	84	5	bands	band	NOUN
fnp-3679	84	6	of	of	ADP
fnp-3679	84	7	interest	interest	NOUN
fnp-3679	84	8	on	on	ADP
fnp-3679	84	9	coomassie	coomassie	ADJ
fnp-3679	84	10	blue	blue	ADJ
fnp-3679	84	11	-	-	PUNCT
fnp-3679	84	12	stained	stain	VERB
fnp-3679	84	13	sds	sds	NOUN
fnp-3679	84	14	-	-	PUNCT
fnp-3679	84	15	page	page	NOUN
fnp-3679	84	16	gels	gel	NOUN
fnp-3679	84	17	were	be	AUX
fnp-3679	84	18	manually	manually	ADV
fnp-3679	84	19	excised	excise	VERB
fnp-3679	84	20	and	and	CCONJ
fnp-3679	84	21	minced	mince	VERB
fnp-3679	84	22	.	.	PUNCT
fnp-3679	85	1	the	the	DET
fnp-3679	85	2	pieces	piece	NOUN
fnp-3679	85	3	were	be	AUX
fnp-3679	85	4	dehydrated	dehydrate	VERB
fnp-3679	85	5	with	with	ADP
fnp-3679	85	6	acetonitrile	acetonitrile	NOUN
fnp-3679	85	7	for	for	ADP
fnp-3679	85	8	10	10	NUM
fnp-3679	85	9	min	min	NOUN
fnp-3679	85	10	,	,	PUNCT
fnp-3679	85	11	vacuum	vacuum	PROPN
fnp-3679	85	12	dried	dry	VERB
fnp-3679	85	13	,	,	PUNCT
fnp-3679	85	14	rehydrated	rehydrate	VERB
fnp-3679	85	15	with	with	ADP
fnp-3679	85	16	5	5	NUM
fnp-3679	85	17	mm	mm	NOUN
fnp-3679	85	18	triphosphine	triphosphine	NOUN
fnp-3679	85	19	hydrochloride	hydrochloride	NOUN
fnp-3679	85	20	in	in	ADP
fnp-3679	85	21	25	25	NUM
fnp-3679	85	22	mm	mm	NOUN
fnp-3679	85	23	ammonium	ammonium	NOUN
fnp-3679	85	24	bicarbonate	bicarbonate	NOUN
fnp-3679	85	25	(	(	PUNCT
fnp-3679	85	26	ph	ph	NOUN
fnp-3679	85	27	8.5	8.5	NUM
fnp-3679	85	28	)	)	PUNCT
fnp-3679	85	29	at	at	ADP
fnp-3679	85	30	37	37	NUM
fnp-3679	85	31	°	°	NOUN
fnp-3679	85	32	c	c	NOUN
fnp-3679	85	33	for	for	ADP
fnp-3679	85	34	1	1	NUM
fnp-3679	85	35	h	h	NOUN
fnp-3679	85	36	and	and	CCONJ
fnp-3679	85	37	then	then	ADV
fnp-3679	85	38	alkylated	alkylate	VERB
fnp-3679	85	39	with	with	ADP
fnp-3679	85	40	100	100	NUM
fnp-3679	85	41	mm	mm	NOUN
fnp-3679	85	42	iodoacetamide	iodoacetamide	NOUN
fnp-3679	85	43	in	in	ADP
fnp-3679	85	44	25	25	NUM
fnp-3679	85	45	mm	mm	NOUN
fnp-3679	85	46	ammonium	ammonium	NOUN
fnp-3679	85	47	bicarbonate	bicarbonate	NOUN
fnp-3679	85	48	(	(	PUNCT
fnp-3679	85	49	ph	ph	NOUN
fnp-3679	85	50	8.5	8.5	NUM
fnp-3679	85	51	)	)	PUNCT
fnp-3679	85	52	at	at	ADP
fnp-3679	85	53	room	room	NOUN
fnp-3679	85	54	temperature	temperature	NOUN
fnp-3679	85	55	for	for	ADP
fnp-3679	85	56	1	1	NUM
fnp-3679	85	57	h.	h.	NOUN
fnp-3679	85	58	the	the	DET
fnp-3679	85	59	pieces	piece	NOUN
fnp-3679	85	60	were	be	AUX
fnp-3679	85	61	washed	wash	VERB
fnp-3679	85	62	twice	twice	ADV
fnp-3679	85	63	with	with	ADP
fnp-3679	85	64	50	50	NUM
fnp-3679	85	65	%	%	NOUN
fnp-3679	85	66	acetonitrile	acetonitrile	NOUN
fnp-3679	85	67	in	in	ADP
fnp-3679	85	68	25	25	NUM
fnp-3679	85	69	mm	mm	NOUN
fnp-3679	85	70	ammonium	ammonium	NOUN
fnp-3679	85	71	bicarbonate	bicarbonate	NOUN
fnp-3679	85	72	(	(	PUNCT
fnp-3679	85	73	ph	ph	NOUN
fnp-3679	85	74	8.5	8.5	NUM
fnp-3679	85	75	)	)	PUNCT
fnp-3679	85	76	for	for	ADP
fnp-3679	85	77	15	15	NUM
fnp-3679	85	78	min	min	NOUN
fnp-3679	85	79	,	,	PUNCT
fnp-3679	85	80	dehydrated	dehydrate	VERB
fnp-3679	85	81	with	with	ADP
fnp-3679	85	82	acetonitrile	acetonitrile	NOUN
fnp-3679	85	83	for	for	ADP
fnp-3679	85	84	10	10	NUM
fnp-3679	85	85	min	min	NOUN
fnp-3679	85	86	,	,	PUNCT
fnp-3679	85	87	dried	dry	VERB
fnp-3679	85	88	,	,	PUNCT
fnp-3679	85	89	and	and	CCONJ
fnp-3679	85	90	digested	digest	VERB
fnp-3679	85	91	in	in	ADP
fnp-3679	85	92	sequencing	sequence	VERB
fnp-3679	85	93	grade	grade	NOUN
fnp-3679	85	94	modified	modify	VERB
fnp-3679	85	95	trypsin	trypsin	NOUN
fnp-3679	85	96	(	(	PUNCT
fnp-3679	85	97	25	25	NUM
fnp-3679	85	98	ng/µl	ng/µl	NUM
fnp-3679	85	99	;	;	PUNCT
fnp-3679	85	100	sigma	sigma	PROPN
fnp-3679	85	101	,	,	PUNCT
fnp-3679	85	102	st	st	PROPN
fnp-3679	85	103	.	.	PROPN
fnp-3679	85	104	louis	louis	PROPN
fnp-3679	85	105	,	,	PUNCT
fnp-3679	85	106	mo	mo	PROPN
fnp-3679	85	107	,	,	PUNCT
fnp-3679	85	108	usa	usa	PROPN
fnp-3679	85	109	,	,	PUNCT
fnp-3679	85	110	cat	cat	NOUN
fnp-3679	85	111	.	.	PUNCT
fnp-3679	86	1	no	no	INTJ
fnp-3679	86	2	.	.	PUNCT
fnp-3679	87	1	t8658	t8658	NOUN
fnp-3679	87	2	)	)	PUNCT
fnp-3679	87	3	in	in	ADP
fnp-3679	87	4	25	25	NUM
fnp-3679	87	5	mm	mm	NOUN
fnp-3679	87	6	ammonium	ammonium	NOUN
fnp-3679	87	7	bicarbonate	bicarbonate	NOUN
fnp-3679	87	8	(	(	PUNCT
fnp-3679	87	9	ph	ph	NOUN
fnp-3679	87	10	8.5	8.5	NUM
fnp-3679	87	11	)	)	PUNCT
fnp-3679	87	12	at	at	ADP
fnp-3679	87	13	37	37	NUM
fnp-3679	87	14	°	°	NOUN
fnp-3679	87	15	c	c	NOUN
fnp-3679	87	16	overnight	overnight	ADV
fnp-3679	87	17	.	.	PUNCT
fnp-3679	88	1	following	follow	VERB
fnp-3679	88	2	digestion	digestion	NOUN
fnp-3679	88	3	,	,	PUNCT
fnp-3679	88	4	tryptic	tryptic	ADJ
fnp-3679	88	5	peptides	peptide	NOUN
fnp-3679	88	6	were	be	AUX
fnp-3679	88	7	extracted	extract	VERB
fnp-3679	88	8	three	three	NUM
fnp-3679	88	9	times	time	NOUN
fnp-3679	88	10	with	with	ADP
fnp-3679	88	11	50	50	NUM
fnp-3679	88	12	%	%	NOUN
fnp-3679	88	13	acetonitrile	acetonitrile	NOUN
fnp-3679	88	14	containing	contain	VERB
fnp-3679	88	15	5	5	NUM
fnp-3679	88	16	%	%	NOUN
fnp-3679	88	17	formic	formic	ADJ
fnp-3679	88	18	acid	acid	NOUN
fnp-3679	88	19	for	for	ADP
fnp-3679	88	20	15	15	NUM
fnp-3679	88	21	min	min	NOUN
fnp-3679	88	22	each	each	DET
fnp-3679	88	23	time	time	NOUN
fnp-3679	88	24	while	while	SCONJ
fnp-3679	88	25	being	be	AUX
fnp-3679	88	26	vortexed	vortexe	VERB
fnp-3679	88	27	.	.	PUNCT
fnp-3679	89	1	the	the	DET
fnp-3679	89	2	extracted	extract	VERB
fnp-3679	89	3	solutions	solution	NOUN
fnp-3679	89	4	were	be	AUX
fnp-3679	89	5	pooled	pool	VERB
fnp-3679	89	6	and	and	CCONJ
fnp-3679	89	7	evaporated	evaporate	VERB
fnp-3679	89	8	to	to	PART
fnp-3679	89	9	dryness	dryness	VERB
fnp-3679	89	10	under	under	ADP
fnp-3679	89	11	vacuum	vacuum	NOUN
fnp-3679	89	12	.	.	PUNCT
fnp-3679	90	1	liquid	liquid	ADJ
fnp-3679	90	2	chromatography	chromatography	NOUN
fnp-3679	90	3	-	-	PUNCT
fnp-3679	90	4	tandem	tandem	NOUN
fnp-3679	90	5	mass	mass	ADJ
fnp-3679	90	6	spectrometry	spectrometry	NOUN
fnp-3679	90	7	(	(	PUNCT
fnp-3679	90	8	lc	lc	PROPN
fnp-3679	90	9	-	-	PUNCT
fnp-3679	90	10	ms	ms	PROPN
fnp-3679	90	11	/	/	SYM
fnp-3679	90	12	ms	ms	NOUN
fnp-3679	90	13	)	)	PUNCT
fnp-3679	90	14	was	be	AUX
fnp-3679	90	15	performed	perform	VERB
fnp-3679	90	16	on	on	ADP
fnp-3679	90	17	an	an	DET
fnp-3679	90	18	integrated	integrate	VERB
fnp-3679	90	19	micro	micro	NOUN
fnp-3679	90	20	-	-	ADJ
fnp-3679	90	21	lc	lc	ADJ
fnp-3679	90	22	-	-	PUNCT
fnp-3679	90	23	orbitrap	orbitrap	NOUN
fnp-3679	90	24	velos	velos	PROPN
fnp-3679	90	25	system	system	NOUN
fnp-3679	90	26	(	(	PUNCT
fnp-3679	90	27	thermo	thermo	NOUN
fnp-3679	90	28	)	)	PUNCT
fnp-3679	90	29	,	,	PUNCT
fnp-3679	90	30	comprising	comprise	VERB
fnp-3679	90	31	a	a	DET
fnp-3679	90	32	waters	water	NOUN
fnp-3679	90	33	caplc	caplc	PROPN
fnp-3679	90	34	microscale	microscale	PROPN
fnp-3679	90	35	chromatography	chromatography	NOUN
fnp-3679	90	36	system	system	NOUN
fnp-3679	90	37	(	(	PUNCT
fnp-3679	90	38	waters	waters	PROPN
fnp-3679	90	39	corp	corp	PROPN
fnp-3679	90	40	.	.	PROPN
fnp-3679	90	41	,	,	PUNCT
fnp-3679	90	42	milford	milford	PROPN
fnp-3679	90	43	,	,	PUNCT
fnp-3679	90	44	ma	ma	PROPN
fnp-3679	90	45	)	)	PUNCT
fnp-3679	90	46	with	with	ADP
fnp-3679	90	47	an	an	DET
fnp-3679	90	48	auto	auto	NOUN
fnp-3679	90	49	-	-	PUNCT
fnp-3679	90	50	sampler	sampler	NOUN
fnp-3679	90	51	,	,	PUNCT
fnp-3679	90	52	a	a	DET
fnp-3679	90	53	stream	stream	NOUN
fnp-3679	90	54	-	-	PUNCT
fnp-3679	90	55	select	select	NOUN
fnp-3679	90	56	module	module	NOUN
fnp-3679	90	57	configured	configure	VERB
fnp-3679	90	58	for	for	ADP
fnp-3679	90	59	pre	pre	ADJ
fnp-3679	90	60	-	-	NOUN
fnp-3679	90	61	column	column	NOUN
fnp-3679	90	62	plus	plus	CCONJ
fnp-3679	90	63	analytical	analytical	ADJ
fnp-3679	90	64	capillary	capillary	ADJ
fnp-3679	90	65	column	column	NOUN
fnp-3679	90	66	,	,	PUNCT
fnp-3679	90	67	and	and	CCONJ
fnp-3679	90	68	an	an	DET
fnp-3679	90	69	orbitrap	orbitrap	NOUN
fnp-3679	90	70	velos	velos	PROPN
fnp-3679	90	71	mass	mass	PROPN
fnp-3679	90	72	spectrometer	spectrometer	NOUN
fnp-3679	90	73	fitted	fit	VERB
fnp-3679	90	74	with	with	ADP
fnp-3679	90	75	an	an	DET
fnp-3679	90	76	h	h	NOUN
fnp-3679	90	77	-	-	PUNCT
fnp-3679	90	78	electrospray	electrospray	ADJ
fnp-3679	90	79	ionizer	ionizer	NOUN
fnp-3679	90	80	probe	probe	NOUN
fnp-3679	90	81	operated	operate	VERB
fnp-3679	90	82	under	under	ADP
fnp-3679	90	83	xcalibur	xcalibur	PROPN
fnp-3679	90	84	2.2	2.2	NUM
fnp-3679	90	85	control	control	NOUN
fnp-3679	90	86	.	.	PUNCT
fnp-3679	91	1	injected	inject	VERB
fnp-3679	91	2	samples	sample	NOUN
fnp-3679	91	3	(	(	PUNCT
fnp-3679	91	4	30	30	NUM
fnp-3679	91	5	µl	µl	NOUN
fnp-3679	91	6	)	)	PUNCT
fnp-3679	91	7	were	be	AUX
fnp-3679	91	8	first	first	ADV
fnp-3679	91	9	trapped	trap	VERB
fnp-3679	91	10	and	and	CCONJ
fnp-3679	91	11	desalted	desalt	VERB
fnp-3679	91	12	isocratically	isocratically	ADV
fnp-3679	91	13	on	on	ADP
fnp-3679	91	14	a	a	DET
fnp-3679	91	15	home	home	NOUN
fnp-3679	91	16	-	-	PUNCT
fnp-3679	91	17	packed	pack	VERB
fnp-3679	91	18	c18	c18	NOUN
fnp-3679	91	19	pre	pre	ADJ
fnp-3679	91	20	-	-	ADJ
fnp-3679	91	21	column	column	ADJ
fnp-3679	91	22	cartridge	cartridge	NOUN
fnp-3679	91	23	(	(	PUNCT
fnp-3679	91	24	everest	everest	PROPN
fnp-3679	91	25	c18	c18	NOUN
fnp-3679	91	26	,	,	PUNCT
fnp-3679	91	27	5	5	NUM
fnp-3679	91	28	µm	µm	ADP
fnp-3679	91	29	particle	particle	NOUN
fnp-3679	91	30	diameter	diameter	NOUN
fnp-3679	91	31	;	;	PUNCT
fnp-3679	91	32	column	column	NOUN
fnp-3679	91	33	dimensions	dimension	NOUN
fnp-3679	91	34	:	:	PUNCT
fnp-3679	91	35	internal	internal	ADJ
fnp-3679	91	36	diameter	diameter	NOUN
fnp-3679	91	37	,	,	PUNCT
fnp-3679	91	38	500	500	NUM
fnp-3679	91	39	µm	µm	NOUN
fnp-3679	91	40	;	;	PUNCT
fnp-3679	91	41	length	length	NOUN
fnp-3679	91	42	,	,	PUNCT
fnp-3679	92	1	15	15	NUM
fnp-3679	92	2	mm	mm	NOUN
fnp-3679	93	1	[	[	X
fnp-3679	93	2	grace	grace	NOUN
fnp-3679	93	3	,	,	PUNCT
fnp-3679	93	4	deerfield	deerfield	PROPN
fnp-3679	93	5	,	,	PUNCT
fnp-3679	93	6	il	il	PROPN
fnp-3679	93	7	]	]	X
fnp-3679	93	8	)	)	PUNCT
fnp-3679	93	9	for	for	ADP
fnp-3679	93	10	6	6	NUM
fnp-3679	93	11	min	min	NOUN
fnp-3679	93	12	with	with	ADP
fnp-3679	93	13	0.1	0.1	NUM
fnp-3679	93	14	%	%	NOUN
fnp-3679	93	15	formic	formic	NOUN
fnp-3679	93	16	acid	acid	NOUN
fnp-3679	93	17	delivered	deliver	VERB
fnp-3679	93	18	by	by	ADP
fnp-3679	93	19	an	an	DET
fnp-3679	93	20	auxiliary	auxiliary	ADJ
fnp-3679	93	21	pump	pump	NOUN
fnp-3679	93	22	at	at	ADP
fnp-3679	93	23	40	40	NUM
fnp-3679	93	24	μl	μl	NUM
fnp-3679	93	25	/	/	SYM
fnp-3679	93	26	min	min	NOUN
fnp-3679	93	27	.	.	PUNCT
fnp-3679	94	1	the	the	DET
fnp-3679	94	2	peptides	peptide	NOUN
fnp-3679	94	3	were	be	AUX
fnp-3679	94	4	then	then	ADV
fnp-3679	94	5	eluted	elute	VERB
fnp-3679	94	6	from	from	ADP
fnp-3679	94	7	the	the	DET
fnp-3679	94	8	pre	pre	NOUN
fnp-3679	94	9	-	-	NOUN
fnp-3679	94	10	column	column	NOUN
fnp-3679	94	11	and	and	CCONJ
fnp-3679	94	12	separated	separate	VERB
fnp-3679	94	13	on	on	ADP
fnp-3679	94	14	an	an	DET
fnp-3679	94	15	ace	ace	NOUN
fnp-3679	94	16	c18	c18	NOUN
fnp-3679	94	17	capillary	capillary	ADJ
fnp-3679	94	18	column	column	NOUN
fnp-3679	94	19	(	(	PUNCT
fnp-3679	94	20	15	15	NUM
fnp-3679	94	21	cm	cm	NOUN
fnp-3679	94	22	x	x	SYM
fnp-3679	94	23	500	500	NUM
fnp-3679	94	24	μm	μm	NUM
fnp-3679	94	25	internal	internal	ADJ
fnp-3679	94	26	diameter	diameter	NOUN
fnp-3679	94	27	)	)	PUNCT
fnp-3679	94	28	packed	pack	VERB
fnp-3679	94	29	with	with	ADP
fnp-3679	94	30	ace	ace	PROPN
fnp-3679	94	31	c18	c18	NOUN
fnp-3679	94	32	-	-	PUNCT
fnp-3679	94	33	300	300	NUM
fnp-3679	94	34	particles	particle	NOUN
fnp-3679	94	35	(	(	PUNCT
fnp-3679	94	36	5	5	NUM
fnp-3679	94	37	µm	µm	NOUN
fnp-3679	94	38	resin	resin	NOUN
fnp-3679	94	39	,	,	PUNCT
fnp-3679	94	40	advanced	advanced	ADJ
fnp-3679	94	41	chromatography	chromatography	NOUN
fnp-3679	94	42	technologies	technology	NOUN
fnp-3679	94	43	,	,	PUNCT
fnp-3679	94	44	aberdeen	aberdeen	PROPN
fnp-3679	94	45	,	,	PUNCT
fnp-3679	94	46	scotland	scotland	PROPN
fnp-3679	94	47	)	)	PUNCT
fnp-3679	94	48	.	.	PUNCT
fnp-3679	95	1	the	the	DET
fnp-3679	95	2	c18	c18	NOUN
fnp-3679	95	3	column	column	NOUN
fnp-3679	95	4	was	be	AUX
fnp-3679	95	5	connected	connect	VERB
fnp-3679	95	6	in	in	ADP
fnp-3679	95	7	-	-	PUNCT
fnp-3679	95	8	line	line	NOUN
fnp-3679	95	9	with	with	ADP
fnp-3679	95	10	the	the	DET
fnp-3679	95	11	mass	mass	NOUN
fnp-3679	95	12	spectrometer	spectrometer	NOUN
fnp-3679	95	13	and	and	CCONJ
fnp-3679	95	14	eluted	elute	VERB
fnp-3679	95	15	at	at	ADP
fnp-3679	95	16	a	a	DET
fnp-3679	95	17	flow	flow	NOUN
fnp-3679	95	18	rate	rate	NOUN
fnp-3679	95	19	of	of	ADP
fnp-3679	95	20	20	20	NUM
fnp-3679	95	21	µl	µl	NOUN
fnp-3679	95	22	/	/	SYM
fnp-3679	95	23	min	min	NOUN
fnp-3679	95	24	with	with	ADP
fnp-3679	95	25	a	a	DET
fnp-3679	95	26	40	40	NUM
fnp-3679	95	27	-	-	PUNCT
fnp-3679	95	28	min	min	NOUN
fnp-3679	95	29	gradient	gradient	NOUN
fnp-3679	95	30	of	of	ADP
fnp-3679	95	31	5	5	NUM
fnp-3679	95	32	-	-	PUNCT
fnp-3679	95	33	to-80	to-80	NUM
fnp-3679	95	34	%	%	NOUN
fnp-3679	95	35	acetonitrile	acetonitrile	NOUN
fnp-3679	95	36	in	in	ADP
fnp-3679	95	37	0.1	0.1	NUM
fnp-3679	95	38	%	%	NOUN
fnp-3679	95	39	formic	formic	ADJ
fnp-3679	95	40	acid	acid	NOUN
fnp-3679	95	41	.	.	PUNCT
fnp-3679	96	1	tandem	tandem	PROPN
fnp-3679	96	2	spectrum	spectrum	PROPN
fnp-3679	96	3	data	datum	NOUN
fnp-3679	96	4	was	be	AUX
fnp-3679	96	5	processed	process	VERB
fnp-3679	96	6	using	use	VERB
fnp-3679	96	7	mascot	mascot	NOUN
fnp-3679	96	8	2.7	2.7	NUM
fnp-3679	96	9	(	(	PUNCT
fnp-3679	96	10	matrix	matrix	NOUN
fnp-3679	96	11	science	science	NOUN
fnp-3679	96	12	,	,	PUNCT
fnp-3679	96	13	boston	boston	PROPN
fnp-3679	96	14	,	,	PUNCT
fnp-3679	96	15	ma	ma	PROPN
fnp-3679	96	16	)	)	PUNCT
fnp-3679	96	17	.	.	PUNCT
fnp-3679	97	1	the	the	DET
fnp-3679	97	2	lists	list	NOUN
fnp-3679	97	3	of	of	ADP
fnp-3679	97	4	peaks	peak	NOUN
fnp-3679	97	5	were	be	AUX
fnp-3679	97	6	used	use	VERB
fnp-3679	97	7	to	to	PART
fnp-3679	97	8	query	query	VERB
fnp-3679	97	9	a	a	DET
fnp-3679	97	10	human	human	ADJ
fnp-3679	97	11	protein	protein	NOUN
fnp-3679	97	12	database	database	NOUN
fnp-3679	97	13	downloaded	download	VERB
fnp-3679	97	14	from	from	ADP
fnp-3679	97	15	national	national	ADJ
fnp-3679	97	16	center	center	NOUN
fnp-3679	97	17	of	of	ADP
fnp-3679	97	18	biotechnology	biotechnology	NOUN
fnp-3679	97	19	information	information	NOUN
fnp-3679	97	20	by	by	ADP
fnp-3679	97	21	setting	set	VERB
fnp-3679	97	22	the	the	DET
fnp-3679	97	23	following	follow	VERB
fnp-3679	97	24	parameters	parameter	NOUN
fnp-3679	97	25	:	:	PUNCT
fnp-3679	97	26	peptide	peptide	ADJ
fnp-3679	97	27	mass	mass	NOUN
fnp-3679	97	28	tolerance	tolerance	NOUN
fnp-3679	97	29	,	,	PUNCT
fnp-3679	97	30	10	10	NUM
fnp-3679	97	31	ppm	ppm	NOUN
fnp-3679	97	32	;	;	PUNCT
fnp-3679	97	33	ms	ms	PROPN
fnp-3679	97	34	/	/	SYM
fnp-3679	97	35	ms	ms	PROPN
fnp-3679	97	36	ion	ion	NOUN
fnp-3679	97	37	mass	mass	NOUN
fnp-3679	97	38	tolerance	tolerance	NOUN
fnp-3679	97	39	,	,	PUNCT
fnp-3679	97	40	0.1	0.1	NUM
fnp-3679	97	41	da	da	NOUN
fnp-3679	97	42	;	;	PUNCT
fnp-3679	97	43	allowing	allow	VERB
fnp-3679	97	44	up	up	ADP
fnp-3679	97	45	to	to	ADP
fnp-3679	97	46	one	one	NUM
fnp-3679	97	47	missed	miss	VERB
fnp-3679	97	48	cleavage	cleavage	NOUN
fnp-3679	97	49	;	;	PUNCT
fnp-3679	97	50	considering	consider	VERB
fnp-3679	97	51	variable	variable	ADJ
fnp-3679	97	52	modifications	modification	NOUN
fnp-3679	97	53	such	such	ADJ
fnp-3679	97	54	as	as	ADP
fnp-3679	97	55	methionine	methionine	NOUN
fnp-3679	97	56	oxidation	oxidation	NOUN
fnp-3679	97	57	,	,	PUNCT
fnp-3679	97	58	cysteine	cysteine	NOUN
fnp-3679	97	59	carboxyamidomethylation	carboxyamidomethylation	NOUN
fnp-3679	97	60	,	,	PUNCT
fnp-3679	97	61	and	and	CCONJ
fnp-3679	97	62	deamidation	deamidation	NOUN
fnp-3679	97	63	.	.	PUNCT
fnp-3679	98	1	only	only	ADV
fnp-3679	98	2	significant	significant	ADJ
fnp-3679	98	3	hits	hit	NOUN
fnp-3679	98	4	as	as	SCONJ
fnp-3679	98	5	defined	define	VERB
fnp-3679	98	6	by	by	ADP
fnp-3679	98	7	mascot	mascot	ADJ
fnp-3679	98	8	probability	probability	NOUN
fnp-3679	98	9	analysis	analysis	NOUN
fnp-3679	98	10	was	be	AUX
fnp-3679	98	11	considered	consider	VERB
fnp-3679	98	12	for	for	ADP
fnp-3679	98	13	a	a	DET
fnp-3679	98	14	positive	positive	ADJ
fnp-3679	98	15	protein	protein	NOUN
fnp-3679	98	16	identification	identification	NOUN
fnp-3679	98	17	.	.	PUNCT
fnp-3679	99	1	immunohistochemistry	immunohistochemistry	NOUN
fnp-3679	99	2	:	:	PUNCT
fnp-3679	99	3	to	to	PART
fnp-3679	99	4	visualize	visualize	VERB
fnp-3679	99	5	desmin	desmin	PROPN
fnp-3679	99	6	,	,	PUNCT
fnp-3679	99	7	its	its	PRON
fnp-3679	99	8	chaperone	chaperone	NOUN
fnp-3679	99	9	protein	protein	NOUN
fnp-3679	99	10	αb	αb	NOUN
fnp-3679	99	11	-	-	NOUN
fnp-3679	99	12	crystallin	crystallin	NOUN
fnp-3679	99	13	,	,	PUNCT
fnp-3679	99	14	and	and	CCONJ
fnp-3679	99	15	known	know	VERB
fnp-3679	99	16	desmin	desmin	NOUN
fnp-3679	99	17	-	-	PUNCT
fnp-3679	99	18	linked	link	VERB
fnp-3679	99	19	intermediate	intermediate	ADJ
fnp-3679	99	20	filament	filament	NOUN
fnp-3679	99	21	proteins	protein	NOUN
fnp-3679	99	22	(	(	PUNCT
fnp-3679	99	23	α	α	NOUN
fnp-3679	99	24	-	-	NOUN
fnp-3679	99	25	spectrin	spectrin	NOUN
fnp-3679	99	26	;	;	PUNCT
fnp-3679	99	27	ankyrin-1	ankyrin-1	NUM
fnp-3679	99	28	;	;	PUNCT
fnp-3679	99	29	plectin	plectin	NOUN
fnp-3679	99	30	;	;	PUNCT
fnp-3679	99	31	zasp	zasp	NOUN
fnp-3679	100	1	[	[	X
fnp-3679	100	2	cypher	cypher	X
fnp-3679	100	3	]	]	X
fnp-3679	100	4	;	;	PUNCT
fnp-3679	100	5	and	and	CCONJ
fnp-3679	100	6	α	α	X
fnp-3679	100	7	-	-	NOUN
fnp-3679	100	8	actinin	actinin	NOUN
fnp-3679	100	9	)	)	PUNCT
fnp-3679	100	10	,	,	PUNCT
fnp-3679	100	11	6-µm	6-µm	NUM
fnp-3679	100	12	thick	thick	ADJ
fnp-3679	100	13	paraffin	paraffin	NOUN
fnp-3679	100	14	sections	section	NOUN
fnp-3679	100	15	were	be	AUX
fnp-3679	100	16	rehydrated	rehydrate	VERB
fnp-3679	100	17	by	by	ADP
fnp-3679	100	18	sequential	sequential	ADJ
fnp-3679	100	19	incubation	incubation	NOUN
fnp-3679	100	20	in	in	ADP
fnp-3679	100	21	a	a	DET
fnp-3679	100	22	series	series	NOUN
fnp-3679	100	23	of	of	ADP
fnp-3679	100	24	xylene	xylene	NOUN
fnp-3679	100	25	,	,	PUNCT
fnp-3679	100	26	absolute	absolute	ADJ
fnp-3679	100	27	ethanol	ethanol	NOUN
fnp-3679	100	28	,	,	PUNCT
fnp-3679	100	29	95	95	NUM
fnp-3679	100	30	%	%	NOUN
fnp-3679	100	31	ethanol	ethanol	NOUN
fnp-3679	100	32	,	,	PUNCT
fnp-3679	100	33	80	80	NUM
fnp-3679	100	34	%	%	NOUN
fnp-3679	100	35	ethanol	ethanol	NOUN
fnp-3679	100	36	,	,	PUNCT
fnp-3679	100	37	and	and	CCONJ
fnp-3679	100	38	deionized	deionize	VERB
fnp-3679	100	39	water	water	NOUN
fnp-3679	100	40	.	.	PUNCT
fnp-3679	101	1	endogenous	endogenous	ADJ
fnp-3679	101	2	peroxidase	peroxidase	NOUN
fnp-3679	101	3	activity	activity	NOUN
fnp-3679	101	4	was	be	AUX
fnp-3679	101	5	suppressed	suppress	VERB
fnp-3679	101	6	by	by	ADP
fnp-3679	101	7	incubation	incubation	NOUN
fnp-3679	101	8	in	in	ADP
fnp-3679	101	9	methanol	methanol	NOUN
fnp-3679	101	10	containing	contain	VERB
fnp-3679	101	11	3	3	NUM
fnp-3679	101	12	%	%	NOUN
fnp-3679	101	13	aqueous	aqueous	ADJ
fnp-3679	101	14	hydrogen	hydrogen	NOUN
fnp-3679	101	15	peroxide	peroxide	NOUN
fnp-3679	101	16	.	.	PUNCT
fnp-3679	102	1	antigen	antigen	PROPN
fnp-3679	102	2	retrieval	retrieval	NOUN
fnp-3679	102	3	,	,	PUNCT
fnp-3679	102	4	background	background	NOUN
fnp-3679	102	5	suppression	suppression	NOUN
fnp-3679	102	6	,	,	PUNCT
fnp-3679	102	7	incubation	incubation	NOUN
fnp-3679	102	8	with	with	ADP
fnp-3679	102	9	polyclonal	polyclonal	ADJ
fnp-3679	102	10	or	or	CCONJ
fnp-3679	102	11	monoclonal	monoclonal	NOUN
fnp-3679	102	12	antibodies	antibody	NOUN
fnp-3679	102	13	,	,	PUNCT
fnp-3679	102	14	secondary	secondary	ADJ
fnp-3679	102	15	biotinylated	biotinylate	VERB
fnp-3679	102	16	anti	anti	ADJ
fnp-3679	102	17	-	-	ADJ
fnp-3679	102	18	rabbit	rabbit	ADJ
fnp-3679	102	19	igg	igg	PROPN
fnp-3679	102	20	(	(	PUNCT
fnp-3679	102	21	for	for	ADP
fnp-3679	102	22	rabbit	rabbit	NOUN
fnp-3679	102	23	polyclonal	polyclonal	ADJ
fnp-3679	102	24	primary	primary	ADJ
fnp-3679	102	25	antibodies	antibody	NOUN
fnp-3679	102	26	)	)	PUNCT
fnp-3679	102	27	or	or	CCONJ
fnp-3679	102	28	anti	anti	ADJ
fnp-3679	102	29	-	-	ADJ
fnp-3679	102	30	mouse	mouse	ADJ
fnp-3679	102	31	igg	igg	NOUN
fnp-3679	102	32	(	(	PUNCT
fnp-3679	102	33	for	for	ADP
fnp-3679	102	34	primary	primary	ADJ
fnp-3679	102	35	mouse	mouse	NOUN
fnp-3679	102	36	monoclonal	monoclonal	NOUN
fnp-3679	102	37	antibodies	antibodie	VERB
fnp-3679	102	38	)	)	PUNCT
fnp-3679	102	39	,	,	PUNCT
fnp-3679	102	40	and	and	CCONJ
fnp-3679	102	41	chromogenic	chromogenic	ADJ
fnp-3679	102	42	solutions	solution	NOUN
fnp-3679	102	43	of	of	ADP
fnp-3679	102	44	diaminobenzidine	diaminobenzidine	NOUN
fnp-3679	102	45	and	and	CCONJ
fnp-3679	102	46	hydrogen	hydrogen	NOUN
fnp-3679	102	47	peroxide	peroxide	NOUN
fnp-3679	102	48	were	be	AUX
fnp-3679	102	49	as	as	ADP
fnp-3679	102	50	described	describe	VERB
fnp-3679	102	51	(	(	PUNCT
fnp-3679	102	52	koeppen	koeppen	PROPN
fnp-3679	102	53	et	et	PROPN
fnp-3679	102	54	al	al	PROPN
fnp-3679	102	55	.	.	PROPN
fnp-3679	102	56	,	,	PUNCT
fnp-3679	102	57	2020	2020	NUM
fnp-3679	102	58	)	)	PUNCT
fnp-3679	102	59	.	.	PUNCT
fnp-3679	103	1	double	double	ADJ
fnp-3679	103	2	-	-	PUNCT
fnp-3679	103	3	label	label	NOUN
fnp-3679	103	4	fluorescence	fluorescence	NOUN
fnp-3679	103	5	and	and	CCONJ
fnp-3679	103	6	immunofluorescence	immunofluorescence	NOUN
fnp-3679	103	7	:	:	PUNCT
fnp-3679	103	8	to	to	PART
fnp-3679	103	9	examine	examine	VERB
fnp-3679	103	10	possible	possible	ADJ
fnp-3679	103	11	amyloidogenicity	amyloidogenicity	NOUN
fnp-3679	103	12	of	of	ADP
fnp-3679	103	13	desmin	desmin	NOUN
fnp-3679	103	14	in	in	ADP
fnp-3679	103	15	fa	fa	PROPN
fnp-3679	103	16	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	103	17	,	,	PUNCT
fnp-3679	103	18	immunofluorescence	immunofluorescence	NOUN
fnp-3679	103	19	of	of	ADP
fnp-3679	103	20	desmin	desmin	ADJ
fnp-3679	103	21	and	and	CCONJ
fnp-3679	103	22	fluorescence	fluorescence	NOUN
fnp-3679	103	23	of	of	ADP
fnp-3679	103	24	congo	congo	PROPN
fnp-3679	103	25	red	red	PROPN
fnp-3679	103	26	were	be	AUX
fnp-3679	103	27	combined	combine	VERB
fnp-3679	103	28	.	.	PUNCT
fnp-3679	104	1	slide	slide	NOUN
fnp-3679	104	2	processing	processing	NOUN
fnp-3679	104	3	for	for	ADP
fnp-3679	104	4	immunofluorescence	immunofluorescence	NOUN
fnp-3679	104	5	was	be	AUX
fnp-3679	104	6	as	as	SCONJ
fnp-3679	104	7	described	describe	VERB
fnp-3679	104	8	before	before	ADV
fnp-3679	104	9	(	(	PUNCT
fnp-3679	104	10	koeppen	koeppen	PROPN
fnp-3679	104	11	et	et	PROPN
fnp-3679	104	12	al	al	PROPN
fnp-3679	104	13	.	.	PROPN
fnp-3679	104	14	,	,	PUNCT
fnp-3679	104	15	2020	2020	NUM
fnp-3679	104	16	)	)	PUNCT
fnp-3679	104	17	,	,	PUNCT
fnp-3679	104	18	and	and	CCONJ
fnp-3679	104	19	the	the	DET
fnp-3679	104	20	fluorophore	fluorophore	NOUN
fnp-3679	104	21	for	for	ADP
fnp-3679	104	22	desmin	desmin	ADJ
fnp-3679	104	23	was	be	AUX
fnp-3679	104	24	alexa	alexa	ADJ
fnp-3679	104	25	fluor	fluor	NOUN
fnp-3679	104	26	488	488	NUM
fnp-3679	104	27	-	-	PUNCT
fnp-3679	104	28	labeled	label	VERB
fnp-3679	104	29	goat	goat	PROPN
fnp-3679	104	30	anti	anti	ADJ
fnp-3679	104	31	-	-	ADJ
fnp-3679	104	32	mouse	mouse	ADJ
fnp-3679	104	33	igg	igg	PROPN
fnp-3679	104	34	(	(	PUNCT
fnp-3679	104	35	jackson	jackson	PROPN
fnp-3679	104	36	immunoresearch	immunoresearch	PROPN
fnp-3679	104	37	,	,	PUNCT
fnp-3679	104	38	west	west	PROPN
fnp-3679	104	39	grove	grove	PROPN
fnp-3679	104	40	,	,	PUNCT
fnp-3679	104	41	pa	pa	PROPN
fnp-3679	104	42	,	,	PUNCT
fnp-3679	104	43	usa	usa	PROPN
fnp-3679	104	44	,	,	PUNCT
fnp-3679	104	45	cat	cat	NOUN
fnp-3679	104	46	.	.	PUNCT
fnp-3679	105	1	no	no	INTJ
fnp-3679	105	2	.	.	NOUN
fnp-3679	106	1	115	115	NUM
fnp-3679	106	2	-	-	SYM
fnp-3679	106	3	545	545	NUM
fnp-3679	106	4	-	-	PUNCT
fnp-3679	106	5	003	003	NUM
fnp-3679	106	6	)	)	PUNCT
fnp-3679	106	7	.	.	PUNCT
fnp-3679	107	1	after	after	ADP
fnp-3679	107	2	washing	washing	NOUN
fnp-3679	107	3	,	,	PUNCT
fnp-3679	107	4	the	the	DET
fnp-3679	107	5	sections	section	NOUN
fnp-3679	107	6	were	be	AUX
fnp-3679	107	7	incubated	incubate	VERB
fnp-3679	107	8	in	in	ADP
fnp-3679	107	9	a	a	DET
fnp-3679	107	10	solution	solution	NOUN
fnp-3679	107	11	of	of	ADP
fnp-3679	107	12	high	high	ADJ
fnp-3679	107	13	ph	ph	ADJ
fnp-3679	107	14	congo	congo	NOUN
fnp-3679	107	15	red	red	ADJ
fnp-3679	107	16	,	,	PUNCT
fnp-3679	107	17	as	as	SCONJ
fnp-3679	107	18	described	describe	VERB
fnp-3679	107	19	by	by	ADP
fnp-3679	107	20	the	the	DET
fnp-3679	107	21	supplier	supplier	NOUN
fnp-3679	107	22	(	(	PUNCT
fnp-3679	107	23	ihc	ihc	PROPN
fnp-3679	107	24	world	world	PROPN
fnp-3679	107	25	,	,	PUNCT
fnp-3679	107	26	woodstock	woodstock	PROPN
fnp-3679	107	27	,	,	PUNCT
fnp-3679	107	28	md	md	PROPN
fnp-3679	107	29	,	,	PUNCT
fnp-3679	107	30	usa	usa	PROPN
fnp-3679	107	31	)	)	PUNCT
fnp-3679	107	32	,	,	PUNCT
fnp-3679	107	33	washed	wash	VERB
fnp-3679	107	34	in	in	ADP
fnp-3679	107	35	water	water	NOUN
fnp-3679	107	36	,	,	PUNCT
fnp-3679	107	37	covered	cover	VERB
fnp-3679	107	38	by	by	ADP
fnp-3679	107	39	pbs	pb	NOUN
fnp-3679	107	40	containing	contain	VERB
fnp-3679	107	41	50	50	NUM
fnp-3679	107	42	%	%	NOUN
fnp-3679	107	43	glycerol	glycerol	NOUN
fnp-3679	107	44	(	(	PUNCT
fnp-3679	107	45	by	by	ADP
fnp-3679	107	46	vol	vol	NOUN
fnp-3679	107	47	)	)	PUNCT
fnp-3679	107	48	,	,	PUNCT
fnp-3679	107	49	and	and	CCONJ
fnp-3679	107	50	cover	cover	NOUN
fnp-3679	107	51	-	-	PUNCT
fnp-3679	107	52	slipped	slip	VERB
fnp-3679	107	53	.	.	PUNCT
fnp-3679	108	1	excitation	excitation	NOUN
fnp-3679	108	2	by	by	ADP
fnp-3679	108	3	laser	laser	NOUN
fnp-3679	108	4	light	light	NOUN
fnp-3679	108	5	at	at	ADP
fnp-3679	108	6	488	488	NUM
fnp-3679	108	7	nm	nm	NOUN
fnp-3679	108	8	was	be	AUX
fnp-3679	108	9	suitable	suitable	ADJ
fnp-3679	108	10	for	for	ADP
fnp-3679	108	11	the	the	DET
fnp-3679	108	12	fluorescence	fluorescence	NOUN
fnp-3679	108	13	of	of	ADP
fnp-3679	108	14	both	both	CCONJ
fnp-3679	108	15	alexa	alexa	ADJ
fnp-3679	108	16	fluor	fluor	NOUN
fnp-3679	108	17	488	488	NUM
fnp-3679	108	18	(	(	PUNCT
fnp-3679	108	19	desmin	desmin	ADJ
fnp-3679	108	20	)	)	PUNCT
fnp-3679	108	21	and	and	CCONJ
fnp-3679	108	22	congo	congo	PROPN
fnp-3679	108	23	red	red	PROPN
fnp-3679	108	24	.	.	PUNCT
fnp-3679	109	1	images	image	NOUN
fnp-3679	109	2	were	be	AUX
fnp-3679	109	3	collected	collect	VERB
fnp-3679	109	4	in	in	ADP
fnp-3679	109	5	a	a	DET
fnp-3679	109	6	zeiss	zeiss	PROPN
fnp-3679	109	7	lsm	lsm	PROPN
fnp-3679	109	8	880	880	NUM
fnp-3679	109	9	laser	laser	NOUN
fnp-3679	109	10	scanning	scan	VERB
fnp-3679	109	11	confocal	confocal	ADJ
fnp-3679	109	12	microscope	microscope	NOUN
fnp-3679	109	13	(	(	PUNCT
fnp-3679	109	14	oberkochen	oberkochen	PROPN
fnp-3679	109	15	,	,	PUNCT
fnp-3679	109	16	germany	germany	PROPN
fnp-3679	109	17	)	)	PUNCT
fnp-3679	109	18	set	set	VERB
fnp-3679	109	19	to	to	ADP
fnp-3679	109	20	a	a	DET
fnp-3679	109	21	band	band	NOUN
fnp-3679	109	22	pass	pass	NOUN
fnp-3679	109	23	of	of	ADP
fnp-3679	109	24	507	507	NUM
fnp-3679	109	25	-	-	SYM
fnp-3679	109	26	544	544	NUM
fnp-3679	109	27	nm	nm	NOUN
fnp-3679	109	28	for	for	ADP
fnp-3679	109	29	alexa	alexa	NOUN
fnp-3679	109	30	fluor	fluor	NOUN
fnp-3679	109	31	488	488	NUM
fnp-3679	109	32	and	and	CCONJ
fnp-3679	109	33	560	560	NUM
fnp-3679	109	34	-	-	SYM
fnp-3679	109	35	600	600	NUM
fnp-3679	109	36	nm	nm	NOUN
fnp-3679	109	37	for	for	SCONJ
fnp-3679	109	38	congo	congo	NOUN
fnp-3679	109	39	red	red	PROPN
fnp-3679	109	40	.	.	PUNCT
fnp-3679	110	1	double	double	ADJ
fnp-3679	110	2	-	-	PUNCT
fnp-3679	110	3	label	label	NOUN
fnp-3679	110	4	immunofluorescence	immunofluorescence	NOUN
fnp-3679	110	5	of	of	ADP
fnp-3679	110	6	the	the	DET
fnp-3679	110	7	pairs	pair	NOUN
fnp-3679	110	8	desmin	desmin	NOUN
fnp-3679	110	9	/	/	SYM
fnp-3679	111	1	αb	αb	NOUN
fnp-3679	111	2	crystallin	crystallin	NOUN
fnp-3679	111	3	and	and	CCONJ
fnp-3679	111	4	desmin	desmin	ADJ
fnp-3679	111	5	/	/	SYM
fnp-3679	111	6	mitochondrial	mitochondrial	NOUN
fnp-3679	112	1	atp5b	atp5b	PRON
fnp-3679	112	2	followed	follow	VERB
fnp-3679	112	3	a	a	DET
fnp-3679	112	4	published	publish	VERB
fnp-3679	112	5	protocol	protocol	NOUN
fnp-3679	112	6	(	(	PUNCT
fnp-3679	112	7	koeppen	koeppen	PROPN
fnp-3679	112	8	et	et	PROPN
fnp-3679	112	9	al	al	PROPN
fnp-3679	112	10	.	.	PROPN
fnp-3679	112	11	,	,	PUNCT
fnp-3679	112	12	2020	2020	NUM
fnp-3679	112	13	)	)	PUNCT
fnp-3679	112	14	.	.	PUNCT
fnp-3679	113	1	atp5b	atp5b	PROPN
fnp-3679	113	2	,	,	PUNCT
fnp-3679	113	3	the	the	DET
fnp-3679	113	4	β	β	X
fnp-3679	113	5	subunit	subunit	NOUN
fnp-3679	113	6	of	of	ADP
fnp-3679	113	7	atp	atp	PROPN
fnp-3679	113	8	synthase	synthase	PROPN
fnp-3679	113	9	f1	f1	NOUN
fnp-3679	113	10	,	,	PUNCT
fnp-3679	113	11	was	be	AUX
fnp-3679	113	12	detected	detect	VERB
fnp-3679	113	13	by	by	ADP
fnp-3679	113	14	a	a	DET
fnp-3679	113	15	polyclonal	polyclonal	ADJ
fnp-3679	113	16	antibody	antibody	NOUN
fnp-3679	113	17	(	(	PUNCT
fnp-3679	113	18	santa	santa	PROPN
fnp-3679	113	19	cruz	cruz	PROPN
fnp-3679	113	20	biotechnology	biotechnology	PROPN
fnp-3679	113	21	,	,	PUNCT
fnp-3679	113	22	dallas	dallas	PROPN
fnp-3679	113	23	,	,	PUNCT
fnp-3679	113	24	tx	tx	PROPN
fnp-3679	113	25	,	,	PUNCT
fnp-3679	113	26	usa	usa	PROPN
fnp-3679	113	27	,	,	PUNCT
fnp-3679	113	28	cat	cat	NOUN
fnp-3679	113	29	.	.	PUNCT
fnp-3679	114	1	no	no	INTJ
fnp-3679	114	2	.	.	PUNCT
fnp-3679	115	1	sc	sc	PROPN
fnp-3679	115	2	33618	33618	NUM
fnp-3679	115	3	)	)	PUNCT
fnp-3679	115	4	and	and	CCONJ
fnp-3679	115	5	cy3	cy3	ADV
fnp-3679	115	6	-	-	PUNCT
fnp-3679	115	7	labeled	label	VERB
fnp-3679	115	8	secondary	secondary	ADJ
fnp-3679	115	9	goat	goat	PROPN
fnp-3679	115	10	anti	anti	ADJ
fnp-3679	115	11	-	-	ADJ
fnp-3679	115	12	rabbit	rabbit	ADJ
fnp-3679	115	13	igg	igg	PROPN
fnp-3679	115	14	(	(	PUNCT
fnp-3679	115	15	jackson	jackson	PROPN
fnp-3679	115	16	immunoresearch	immunoresearch	PROPN
fnp-3679	115	17	,	,	PUNCT
fnp-3679	115	18	cat	cat	NOUN
fnp-3679	115	19	.	.	PUNCT
fnp-3679	116	1	no	no	INTJ
fnp-3679	116	2	.	.	NOUN
fnp-3679	116	3	111	111	NUM
fnp-3679	116	4	-	-	PUNCT
fnp-3679	116	5	165	165	NUM
fnp-3679	116	6	-	-	PUNCT
fnp-3679	116	7	003	003	NUM
fnp-3679	116	8	)	)	PUNCT
fnp-3679	116	9	.	.	PUNCT
fnp-3679	117	1	results	result	VERB
fnp-3679	117	2	antibody	antibody	NOUN
fnp-3679	117	3	microarray	microarray	NOUN
fnp-3679	117	4	of	of	ADP
fnp-3679	117	5	heart	heart	NOUN
fnp-3679	117	6	lysates	lysate	NOUN
fnp-3679	117	7	:	:	PUNCT
fnp-3679	117	8	each	each	DET
fnp-3679	117	9	dot	dot	NOUN
fnp-3679	117	10	in	in	ADP
fnp-3679	117	11	the	the	DET
fnp-3679	117	12	panels	panel	NOUN
fnp-3679	117	13	of	of	ADP
fnp-3679	117	14	figure	figure	NOUN
fnp-3679	117	15	1	1	NUM
fnp-3679	117	16	represents	represent	VERB
fnp-3679	117	17	a	a	DET
fnp-3679	117	18	unique	unique	ADJ
fnp-3679	117	19	validated	validated	ADJ
fnp-3679	117	20	antibody	antibody	NOUN
fnp-3679	117	21	,	,	PUNCT
fnp-3679	117	22	and	and	CCONJ
fnp-3679	117	23	the	the	DET
fnp-3679	117	24	legend	legend	NOUN
fnp-3679	117	25	describes	describe	VERB
fnp-3679	117	26	how	how	SCONJ
fnp-3679	117	27	fluorescent	fluorescent	ADJ
fnp-3679	117	28	signals	signal	NOUN
fnp-3679	117	29	of	of	ADP
fnp-3679	117	30	fa	fa	NOUN
fnp-3679	117	31	and	and	CCONJ
fnp-3679	117	32	controls	control	NOUN
fnp-3679	117	33	were	be	AUX
fnp-3679	117	34	superimposed	superimpose	VERB
fnp-3679	117	35	and	and	CCONJ
fnp-3679	117	36	analyzed	analyze	VERB
fnp-3679	117	37	.	.	PUNCT
fnp-3679	118	1	thirteen	thirteen	NUM
fnp-3679	118	2	proteins	protein	NOUN
fnp-3679	118	3	were	be	AUX
fnp-3679	118	4	upregulated	upregulate	VERB
fnp-3679	118	5	to	to	ADP
fnp-3679	118	6	variable	variable	ADJ
fnp-3679	118	7	degrees	degree	NOUN
fnp-3679	118	8	on	on	ADP
fnp-3679	118	9	the	the	DET
fnp-3679	118	10	900	900	NUM
fnp-3679	118	11	-	-	PUNCT
fnp-3679	118	12	antibody	antibody	NOUN
fnp-3679	118	13	microarray	microarray	NOUN
fnp-3679	118	14	.	.	PUNCT
fnp-3679	119	1	when	when	SCONJ
fnp-3679	119	2	expressed	express	VERB
fnp-3679	119	3	as	as	ADP
fnp-3679	119	4	percent	percent	NOUN
fnp-3679	119	5	change	change	NOUN
fnp-3679	119	6	from	from	ADP
fnp-3679	119	7	control	control	NOUN
fnp-3679	119	8	(	(	PUNCT
fnp-3679	119	9	%	%	INTJ
fnp-3679	119	10	cfc	cfc	NOUN
fnp-3679	119	11	)	)	PUNCT
fnp-3679	119	12	,	,	PUNCT
fnp-3679	119	13	the	the	DET
fnp-3679	119	14	following	follow	VERB
fnp-3679	119	15	proteins	protein	NOUN
fnp-3679	119	16	stood	stand	VERB
fnp-3679	119	17	out	out	ADP
fnp-3679	119	18	:	:	PUNCT
fnp-3679	119	19	adducin	adducin	ADJ
fnp-3679	119	20	,	,	PUNCT
fnp-3679	119	21	%	%	INTJ
fnp-3679	119	22	cfc	cfc	PROPN
fnp-3679	119	23	210	210	NUM
fnp-3679	119	24	;	;	PUNCT
fnp-3679	119	25	αb	αb	PROPN
fnp-3679	119	26	-	-	PUNCT
fnp-3679	119	27	crystallin	crystallin	NOUN
fnp-3679	119	28	,	,	PUNCT
fnp-3679	119	29	%	%	INTJ
fnp-3679	119	30	cfc	cfc	PROPN
fnp-3679	119	31	194	194	NUM
fnp-3679	119	32	;	;	PUNCT
fnp-3679	119	33	insulin	insulin	NOUN
fnp-3679	119	34	receptor	receptor	NOUN
fnp-3679	119	35	substrate	substrate	NOUN
fnp-3679	119	36	,	,	PUNCT
fnp-3679	119	37	%	%	INTJ
fnp-3679	119	38	cfc	cfc	PROPN
fnp-3679	119	39	324	324	NUM
fnp-3679	119	40	;	;	PUNCT
fnp-3679	119	41	serine	serine	NOUN
fnp-3679	119	42	/	/	SYM
fnp-3679	119	43	threonine	threonine	ADJ
fnp-3679	119	44	kinase	kinase	PROPN
fnp-3679	119	45	type	type	NOUN
fnp-3679	119	46	4	4	NUM
fnp-3679	119	47	,	,	PUNCT
fnp-3679	119	48	%	%	INTJ
fnp-3679	119	49	cfc	cfc	PROPN
fnp-3679	119	50	103	103	NUM
fnp-3679	119	51	;	;	PUNCT
fnp-3679	119	52	ribosomal	ribosomal	NOUN
fnp-3679	119	53	protein	protein	NOUN
fnp-3679	119	54	s	s	PART
fnp-3679	119	55	kinase	kinase	NOUN
fnp-3679	119	56	alpha	alpha	NOUN
fnp-3679	119	57	3	3	NUM
fnp-3679	119	58	,	,	PUNCT
fnp-3679	119	59	%	%	INTJ
fnp-3679	119	60	cfc	cfc	PROPN
fnp-3679	119	61	149	149	NUM
fnp-3679	119	62	.	.	PUNCT
fnp-3679	120	1	the	the	DET
fnp-3679	120	2	1150	1150	NUM
fnp-3679	120	3	-	-	PUNCT
fnp-3679	120	4	antibody	antibody	NOUN
fnp-3679	120	5	microarray	microarray	NOUN
fnp-3679	120	6	of	of	ADP
fnp-3679	120	7	kinexus	kinexus	PROPN
fnp-3679	120	8	(	(	PUNCT
fnp-3679	120	9	yue	yue	PROPN
fnp-3679	120	10	,	,	PUNCT
fnp-3679	120	11	et	et	PROPN
fnp-3679	120	12	al	al	PROPN
fnp-3679	120	13	,	,	PUNCT
fnp-3679	120	14	2018	2018	NUM
fnp-3679	120	15	)	)	PUNCT
fnp-3679	120	16	yielded	yield	VERB
fnp-3679	120	17	modest	modest	ADJ
fnp-3679	120	18	upregulation	upregulation	NOUN
fnp-3679	120	19	of	of	ADP
fnp-3679	120	20	23	23	NUM
fnp-3679	120	21	other	other	ADJ
fnp-3679	120	22	proteins	protein	NOUN
fnp-3679	120	23	that	that	PRON
fnp-3679	120	24	were	be	AUX
fnp-3679	120	25	not	not	PART
fnp-3679	120	26	further	far	ADV
fnp-3679	120	27	analyzed	analyze	VERB
fnp-3679	120	28	.	.	PUNCT
fnp-3679	121	1	the	the	DET
fnp-3679	121	2	up	up	NOUN
fnp-3679	121	3	-	-	PUNCT
fnp-3679	121	4	regulation	regulation	NOUN
fnp-3679	121	5	of	of	ADP
fnp-3679	121	6	αb	αb	NOUN
fnp-3679	121	7	-	-	PUNCT
fnp-3679	121	8	crystallin	crystallin	NOUN
fnp-3679	121	9	prompted	prompt	VERB
fnp-3679	121	10	a	a	DET
fnp-3679	121	11	more	more	ADV
fnp-3679	121	12	detailed	detailed	ADJ
fnp-3679	121	13	study	study	NOUN
fnp-3679	121	14	of	of	ADP
fnp-3679	121	15	this	this	DET
fnp-3679	121	16	protein	protein	NOUN
fnp-3679	121	17	and	and	CCONJ
fnp-3679	121	18	its	its	PRON
fnp-3679	121	19	partner	partner	NOUN
fnp-3679	121	20	,	,	PUNCT
fnp-3679	121	21	desmin	desmin	ADJ
fnp-3679	121	22	,	,	PUNCT
fnp-3679	121	23	by	by	ADP
fnp-3679	121	24	sds	sds	PROPN
fnp-3679	121	25	-	-	PUNCT
fnp-3679	121	26	page	page	NOUN
fnp-3679	121	27	,	,	PUNCT
fnp-3679	121	28	western	western	ADJ
fnp-3679	121	29	blots	blot	NOUN
fnp-3679	121	30	,	,	PUNCT
fnp-3679	121	31	mass	mass	ADJ
fnp-3679	121	32	spectrometry	spectrometry	NOUN
fnp-3679	121	33	,	,	PUNCT
fnp-3679	121	34	and	and	CCONJ
fnp-3679	121	35	double	double	ADJ
fnp-3679	121	36	-	-	PUNCT
fnp-3679	121	37	label	label	NOUN
fnp-3679	121	38	immunofluorescence	immunofluorescence	NOUN
fnp-3679	121	39	(	(	PUNCT
fnp-3679	121	40	figs	fig	NOUN
fnp-3679	121	41	.	.	PUNCT
fnp-3679	122	1	2	2	NUM
fnp-3679	122	2	-	-	SYM
fnp-3679	122	3	8)	8)	NUM
fnp-3679	122	4	.	.	PUNCT
fnp-3679	122	5	figure	figure	NOUN
fnp-3679	122	6	1	1	NUM
fnp-3679	122	7	.	.	PUNCT
fnp-3679	123	1	antibody	antibody	NOUN
fnp-3679	123	2	microarray	microarray	NOUN
fnp-3679	123	3	of	of	ADP
fnp-3679	123	4	pooled	pool	VERB
fnp-3679	123	5	heart	heart	NOUN
fnp-3679	123	6	lysates	lysate	NOUN
fnp-3679	123	7	of	of	ADP
fnp-3679	123	8	9	9	NUM
fnp-3679	123	9	fa	fa	NOUN
fnp-3679	123	10	patients	patient	NOUN
fnp-3679	123	11	(	(	PUNCT
fnp-3679	123	12	left	leave	VERB
fnp-3679	123	13	upper	upper	ADJ
fnp-3679	123	14	panel	panel	NOUN
fnp-3679	123	15	)	)	PUNCT
fnp-3679	123	16	and	and	CCONJ
fnp-3679	123	17	9	9	NUM
fnp-3679	123	18	normal	normal	ADJ
fnp-3679	123	19	controls	control	NOUN
fnp-3679	123	20	(	(	PUNCT
fnp-3679	123	21	left	leave	VERB
fnp-3679	123	22	lower	low	ADJ
fnp-3679	123	23	panel	panel	NOUN
fnp-3679	123	24	)	)	PUNCT
fnp-3679	123	25	.	.	PUNCT
fnp-3679	124	1	in	in	ADP
fnp-3679	124	2	the	the	DET
fnp-3679	124	3	smaller	small	ADJ
fnp-3679	124	4	panels	panel	NOUN
fnp-3679	124	5	,	,	PUNCT
fnp-3679	124	6	pseudocolors	pseudocolor	NOUN
fnp-3679	124	7	represent	represent	VERB
fnp-3679	124	8	high	high	ADJ
fnp-3679	124	9	fluorescence	fluorescence	NOUN
fnp-3679	124	10	(	(	PUNCT
fnp-3679	124	11	red	red	ADJ
fnp-3679	124	12	)	)	PUNCT
fnp-3679	124	13	and	and	CCONJ
fnp-3679	124	14	lower	low	ADJ
fnp-3679	124	15	fluorescence	fluorescence	NOUN
fnp-3679	124	16	(	(	PUNCT
fnp-3679	124	17	blue	blue	ADJ
fnp-3679	124	18	)	)	PUNCT
fnp-3679	124	19	.	.	PUNCT
fnp-3679	125	1	intermediate	intermediate	ADJ
fnp-3679	125	2	fluorescence	fluorescence	NOUN
fnp-3679	125	3	intensity	intensity	NOUN
fnp-3679	125	4	is	be	AUX
fnp-3679	125	5	represented	represent	VERB
fnp-3679	125	6	by	by	ADP
fnp-3679	125	7	green	green	ADJ
fnp-3679	125	8	and	and	CCONJ
fnp-3679	125	9	yellow	yellow	ADJ
fnp-3679	125	10	,	,	PUNCT
fnp-3679	125	11	in	in	ADP
fnp-3679	125	12	that	that	DET
fnp-3679	125	13	order	order	NOUN
fnp-3679	125	14	.	.	PUNCT
fnp-3679	126	1	the	the	DET
fnp-3679	126	2	larger	large	ADJ
fnp-3679	126	3	image	image	NOUN
fnp-3679	126	4	was	be	AUX
fnp-3679	126	5	created	create	VERB
fnp-3679	126	6	by	by	ADP
fnp-3679	126	7	overlaying	overlay	VERB
fnp-3679	126	8	the	the	DET
fnp-3679	126	9	fa	fa	PROPN
fnp-3679	126	10	and	and	CCONJ
fnp-3679	126	11	control	control	NOUN
fnp-3679	126	12	images	image	NOUN
fnp-3679	126	13	(	(	PUNCT
fnp-3679	126	14	fa	fa	NOUN
fnp-3679	126	15	on	on	ADP
fnp-3679	126	16	top	top	NOUN
fnp-3679	126	17	)	)	PUNCT
fnp-3679	126	18	.	.	PUNCT
fnp-3679	127	1	all	all	DET
fnp-3679	127	2	spots	spot	NOUN
fnp-3679	127	3	of	of	ADP
fnp-3679	127	4	the	the	DET
fnp-3679	127	5	control	control	NOUN
fnp-3679	127	6	image	image	NOUN
fnp-3679	127	7	were	be	AUX
fnp-3679	127	8	made	make	VERB
fnp-3679	127	9	blue	blue	ADJ
fnp-3679	127	10	,	,	PUNCT
fnp-3679	127	11	and	and	CCONJ
fnp-3679	127	12	all	all	DET
fnp-3679	127	13	fa	fa	NOUN
fnp-3679	127	14	spots	spot	NOUN
fnp-3679	127	15	were	be	AUX
fnp-3679	127	16	made	make	VERB
fnp-3679	127	17	red	red	ADJ
fnp-3679	127	18	.	.	PUNCT
fnp-3679	128	1	using	use	VERB
fnp-3679	128	2	adobe	adobe	PROPN
fnp-3679	128	3	photoshop	photoshop	PROPN
fnp-3679	128	4	technology	technology	PROPN
fnp-3679	128	5	,	,	PUNCT
fnp-3679	128	6	the	the	DET
fnp-3679	128	7	fa	fa	NOUN
fnp-3679	128	8	images	image	NOUN
fnp-3679	128	9	on	on	ADP
fnp-3679	128	10	top	top	NOUN
fnp-3679	128	11	were	be	AUX
fnp-3679	128	12	rendered	render	VERB
fnp-3679	128	13	50	50	NUM
fnp-3679	128	14	%	%	NOUN
fnp-3679	128	15	transparent	transparent	ADJ
fnp-3679	128	16	so	so	SCONJ
fnp-3679	128	17	that	that	SCONJ
fnp-3679	128	18	the	the	DET
fnp-3679	128	19	bottom	bottom	ADJ
fnp-3679	128	20	spots	spot	NOUN
fnp-3679	128	21	are	be	AUX
fnp-3679	128	22	white	white	ADJ
fnp-3679	128	23	.	.	PUNCT
fnp-3679	129	1	if	if	SCONJ
fnp-3679	129	2	fa	fa	PROPN
fnp-3679	129	3	intensity	intensity	NOUN
fnp-3679	129	4	was	be	AUX
fnp-3679	129	5	higher	high	ADJ
fnp-3679	129	6	than	than	ADP
fnp-3679	129	7	that	that	PRON
fnp-3679	129	8	of	of	ADP
fnp-3679	129	9	the	the	DET
fnp-3679	129	10	matching	matching	NOUN
fnp-3679	129	11	control	control	NOUN
fnp-3679	129	12	,	,	PUNCT
fnp-3679	129	13	the	the	DET
fnp-3679	129	14	spot	spot	NOUN
fnp-3679	129	15	appears	appear	VERB
fnp-3679	129	16	as	as	ADP
fnp-3679	129	17	red	red	ADJ
fnp-3679	129	18	.	.	PUNCT
fnp-3679	130	1	if	if	SCONJ
fnp-3679	130	2	the	the	DET
fnp-3679	130	3	composite	composite	ADJ
fnp-3679	130	4	signal	signal	NOUN
fnp-3679	130	5	is	be	AUX
fnp-3679	130	6	blue	blue	ADJ
fnp-3679	130	7	,	,	PUNCT
fnp-3679	130	8	the	the	DET
fnp-3679	130	9	signal	signal	NOUN
fnp-3679	130	10	in	in	ADP
fnp-3679	130	11	fa	fa	PROPN
fnp-3679	130	12	was	be	AUX
fnp-3679	130	13	lower	low	ADJ
fnp-3679	130	14	than	than	ADP
fnp-3679	130	15	that	that	PRON
fnp-3679	130	16	of	of	ADP
fnp-3679	130	17	the	the	DET
fnp-3679	130	18	control	control	NOUN
fnp-3679	130	19	.	.	PUNCT
fnp-3679	131	1	pooling	pool	VERB
fnp-3679	131	2	of	of	ADP
fnp-3679	131	3	lysates	lysate	NOUN
fnp-3679	131	4	was	be	AUX
fnp-3679	131	5	intended	intend	VERB
fnp-3679	131	6	to	to	PART
fnp-3679	131	7	control	control	VERB
fnp-3679	131	8	for	for	ADP
fnp-3679	131	9	between	between	ADP
fnp-3679	131	10	-	-	PUNCT
fnp-3679	131	11	samples	sample	NOUN
fnp-3679	131	12	variability	variability	NOUN
fnp-3679	131	13	,	,	PUNCT
fnp-3679	131	14	and	and	CCONJ
fnp-3679	131	15	performance	performance	NOUN
fnp-3679	131	16	in	in	ADP
fnp-3679	131	17	triplicate	triplicate	NOUN
fnp-3679	131	18	allowed	allow	VERB
fnp-3679	131	19	statistical	statistical	ADJ
fnp-3679	131	20	analysis	analysis	NOUN
fnp-3679	131	21	by	by	ADP
fnp-3679	131	22	t	t	NOUN
fnp-3679	131	23	-	-	PUNCT
fnp-3679	131	24	testing	testing	NOUN
fnp-3679	131	25	.	.	PUNCT
fnp-3679	132	1	the	the	DET
fnp-3679	132	2	next	next	ADJ
fnp-3679	132	3	step	step	NOUN
fnp-3679	132	4	in	in	ADP
fnp-3679	132	5	the	the	DET
fnp-3679	132	6	experiment	experiment	NOUN
fnp-3679	132	7	was	be	AUX
fnp-3679	132	8	sds	sds	NOUN
fnp-3679	132	9	-	-	PUNCT
fnp-3679	132	10	page	page	NOUN
fnp-3679	132	11	and	and	CCONJ
fnp-3679	132	12	western	western	ADJ
fnp-3679	132	13	blotting	blotting	NOUN
fnp-3679	132	14	of	of	ADP
fnp-3679	132	15	proteins	protein	NOUN
fnp-3679	132	16	in	in	ADP
fnp-3679	132	17	pooled	pooled	ADJ
fnp-3679	132	18	and	and	CCONJ
fnp-3679	132	19	individual	individual	ADJ
fnp-3679	132	20	lysates	lysate	NOUN
fnp-3679	132	21	.	.	PUNCT
fnp-3679	133	1	frataxin	frataxin	PROPN
fnp-3679	133	2	levels	level	NOUN
fnp-3679	133	3	:	:	PUNCT
fnp-3679	133	4	the	the	DET
fnp-3679	133	5	frataxin	frataxin	ADJ
fnp-3679	133	6	level	level	NOUN
fnp-3679	133	7	in	in	ADP
fnp-3679	133	8	12	12	NUM
fnp-3679	133	9	fa	fa	NOUN
fnp-3679	133	10	heart	heart	NOUN
fnp-3679	133	11	lysates	lysate	NOUN
fnp-3679	133	12	(	(	PUNCT
fnp-3679	133	13	mean	mean	PROPN
fnp-3679	133	14	±	±	NUM
fnp-3679	133	15	standard	standard	ADJ
fnp-3679	133	16	deviation	deviation	NOUN
fnp-3679	133	17	)	)	PUNCT
fnp-3679	133	18	was	be	AUX
fnp-3679	133	19	23.3±3.5	23.3±3.5	NUM
fnp-3679	133	20	ng	ng	PROPN
fnp-3679	133	21	/	/	SYM
fnp-3679	133	22	g	g	PROPN
fnp-3679	133	23	wet	wet	ADJ
fnp-3679	133	24	weight	weight	NOUN
fnp-3679	133	25	.	.	PUNCT
fnp-3679	134	1	in	in	ADP
fnp-3679	134	2	4	4	NUM
fnp-3679	134	3	control	control	NOUN
fnp-3679	134	4	heart	heart	NOUN
fnp-3679	134	5	lysates	lysate	NOUN
fnp-3679	134	6	the	the	DET
fnp-3679	134	7	level	level	NOUN
fnp-3679	134	8	was	be	AUX
fnp-3679	134	9	522.5	522.5	NUM
fnp-3679	134	10	±	±	NUM
fnp-3679	134	11	35	35	NUM
fnp-3679	134	12	ng	ng	PROPN
fnp-3679	134	13	/	/	SYM
fnp-3679	134	14	g	g	PROPN
fnp-3679	134	15	wet	wet	ADJ
fnp-3679	134	16	weight	weight	NOUN
fnp-3679	134	17	.	.	PUNCT
fnp-3679	135	1	the	the	DET
fnp-3679	135	2	difference	difference	NOUN
fnp-3679	135	3	was	be	AUX
fnp-3679	135	4	significant	significant	ADJ
fnp-3679	135	5	at	at	ADP
fnp-3679	135	6	p=0.022	p=0.022	NOUN
fnp-3679	135	7	.	.	PUNCT
fnp-3679	136	1	western	western	ADJ
fnp-3679	136	2	blots	blot	NOUN
fnp-3679	136	3	:	:	PUNCT
fnp-3679	136	4	figure	figure	NOUN
fnp-3679	136	5	2	2	NUM
fnp-3679	136	6	shows	show	VERB
fnp-3679	136	7	a	a	DET
fnp-3679	136	8	western	western	ADJ
fnp-3679	136	9	blot	blot	NOUN
fnp-3679	136	10	of	of	ADP
fnp-3679	136	11	desmin	desmin	NOUN
fnp-3679	136	12	and	and	CCONJ
fnp-3679	136	13	frataxin	frataxin	NOUN
fnp-3679	136	14	in	in	ADP
fnp-3679	136	15	pooled	pool	VERB
fnp-3679	136	16	fa	fa	NOUN
fnp-3679	136	17	heart	heart	NOUN
fnp-3679	136	18	lysates	lysate	NOUN
fnp-3679	136	19	.	.	PUNCT
fnp-3679	137	1	the	the	DET
fnp-3679	137	2	pooled	pool	VERB
fnp-3679	137	3	lysates	lysate	NOUN
fnp-3679	137	4	represent	represent	VERB
fnp-3679	137	5	equal	equal	ADJ
fnp-3679	137	6	additions	addition	NOUN
fnp-3679	137	7	of	of	ADP
fnp-3679	137	8	the	the	DET
fnp-3679	137	9	first	first	ADJ
fnp-3679	137	10	6	6	NUM
fnp-3679	137	11	fa	fa	NOUN
fnp-3679	137	12	cases	case	NOUN
fnp-3679	137	13	shown	show	VERB
fnp-3679	137	14	in	in	ADP
fnp-3679	137	15	figure	figure	NOUN
fnp-3679	137	16	3	3	NUM
fnp-3679	137	17	.	.	PUNCT
fnp-3679	138	1	the	the	DET
fnp-3679	138	2	polyclonal	polyclonal	ADJ
fnp-3679	138	3	antibody	antibody	NOUN
fnp-3679	138	4	to	to	PART
fnp-3679	138	5	desmin	desmin	PROPN
fnp-3679	138	6	revealed	reveal	VERB
fnp-3679	138	7	a	a	DET
fnp-3679	138	8	low	low	ADJ
fnp-3679	138	9	intensity	intensity	NOUN
fnp-3679	138	10	band	band	NOUN
fnp-3679	138	11	at	at	ADP
fnp-3679	138	12	53	53	NUM
fnp-3679	138	13	kda	kda	NOUN
fnp-3679	138	14	which	which	PRON
fnp-3679	138	15	represents	represent	VERB
fnp-3679	138	16	the	the	DET
fnp-3679	138	17	canonical	canonical	ADJ
fnp-3679	138	18	protein	protein	NOUN
fnp-3679	138	19	.	.	PUNCT
fnp-3679	139	1	the	the	DET
fnp-3679	139	2	strongest	strong	ADJ
fnp-3679	139	3	desmin	desmin	ADJ
fnp-3679	139	4	signal	signal	NOUN
fnp-3679	139	5	occurred	occur	VERB
fnp-3679	139	6	from	from	ADP
fnp-3679	139	7	a	a	DET
fnp-3679	139	8	fragment	fragment	NOUN
fnp-3679	139	9	of	of	ADP
fnp-3679	139	10	approximately	approximately	ADV
fnp-3679	139	11	45	45	NUM
fnp-3679	139	12	kda	kda	NOUN
fnp-3679	139	13	.	.	PUNCT
fnp-3679	140	1	mass	mass	PROPN
fnp-3679	140	2	spectrometric	spectrometric	ADJ
fnp-3679	140	3	analysis	analysis	NOUN
fnp-3679	140	4	of	of	ADP
fnp-3679	140	5	this	this	DET
fnp-3679	140	6	fragment	fragment	NOUN
fnp-3679	140	7	(	(	PUNCT
fnp-3679	140	8	fig	fig	NOUN
fnp-3679	140	9	.	.	NOUN
fnp-3679	141	1	2	2	X
fnp-3679	141	2	)	)	PUNCT
fnp-3679	141	3	confirmed	confirm	VERB
fnp-3679	141	4	its	its	PRON
fnp-3679	141	5	derivation	derivation	NOUN
fnp-3679	141	6	from	from	ADP
fnp-3679	141	7	desmin	desmin	PROPN
fnp-3679	141	8	.	.	PUNCT
fnp-3679	142	1	while	while	SCONJ
fnp-3679	142	2	pooling	pool	VERB
fnp-3679	142	3	of	of	ADP
fnp-3679	142	4	12	12	NUM
fnp-3679	142	5	heart	heart	NOUN
fnp-3679	142	6	lysates	lysate	NOUN
fnp-3679	142	7	was	be	AUX
fnp-3679	142	8	useful	useful	ADJ
fnp-3679	142	9	in	in	ADP
fnp-3679	142	10	the	the	DET
fnp-3679	142	11	control	control	NOUN
fnp-3679	142	12	of	of	ADP
fnp-3679	142	13	inter	inter	ADJ
fnp-3679	142	14	-	-	ADJ
fnp-3679	142	15	sample	sample	ADJ
fnp-3679	142	16	variability	variability	NOUN
fnp-3679	142	17	in	in	ADP
fnp-3679	142	18	fa	fa	PROPN
fnp-3679	142	19	,	,	PUNCT
fnp-3679	142	20	the	the	DET
fnp-3679	142	21	western	western	ADJ
fnp-3679	142	22	blot	blot	NOUN
fnp-3679	142	23	in	in	ADP
fnp-3679	142	24	figure	figure	NOUN
fnp-3679	142	25	3	3	NUM
fnp-3679	142	26	shows	show	VERB
fnp-3679	142	27	that	that	SCONJ
fnp-3679	142	28	the	the	DET
fnp-3679	142	29	desmin	desmin	ADJ
fnp-3679	142	30	fragment	fragment	NOUN
fnp-3679	142	31	is	be	AUX
fnp-3679	142	32	shared	share	VERB
fnp-3679	142	33	by	by	ADP
fnp-3679	142	34	all	all	DET
fnp-3679	142	35	fa	fa	NOUN
fnp-3679	142	36	samples	sample	NOUN
fnp-3679	142	37	.	.	PUNCT
fnp-3679	143	1	the	the	DET
fnp-3679	143	2	qualitative	qualitative	ADJ
fnp-3679	143	3	intensity	intensity	NOUN
fnp-3679	143	4	of	of	ADP
fnp-3679	143	5	the	the	DET
fnp-3679	143	6	desmin	desmin	ADJ
fnp-3679	143	7	band	band	NOUN
fnp-3679	143	8	did	do	AUX
fnp-3679	143	9	not	not	PART
fnp-3679	143	10	correlate	correlate	VERB
fnp-3679	143	11	with	with	ADP
fnp-3679	143	12	the	the	DET
fnp-3679	143	13	length	length	NOUN
fnp-3679	143	14	of	of	ADP
fnp-3679	143	15	the	the	DET
fnp-3679	143	16	gaa	gaa	PROPN
fnp-3679	143	17	trinucleotide	trinucleotide	NOUN
fnp-3679	143	18	repeat	repeat	NOUN
fnp-3679	143	19	expansions	expansion	NOUN
fnp-3679	143	20	in	in	ADP
fnp-3679	143	21	the	the	DET
fnp-3679	143	22	shorter	short	ADJ
fnp-3679	143	23	allele	allele	NOUN
fnp-3679	143	24	of	of	ADP
fnp-3679	143	25	the	the	DET
fnp-3679	143	26	frataxin	frataxin	NOUN
fnp-3679	143	27	gene	gene	NOUN
fnp-3679	143	28	(	(	PUNCT
fnp-3679	143	29	fig	fig	NOUN
fnp-3679	143	30	.	.	PUNCT
fnp-3679	144	1	3	3	NUM
fnp-3679	144	2	)	)	PUNCT
fnp-3679	144	3	.	.	PUNCT
fnp-3679	145	1	a	a	DET
fnp-3679	145	2	comparable	comparable	ADJ
fnp-3679	145	3	desmin	desmin	NOUN
fnp-3679	145	4	isoprotein	isoprotein	ADP
fnp-3679	145	5	is	be	AUX
fnp-3679	145	6	also	also	ADV
fnp-3679	145	7	present	present	ADJ
fnp-3679	145	8	in	in	ADP
fnp-3679	145	9	one	one	NUM
fnp-3679	145	10	normal	normal	ADJ
fnp-3679	145	11	control	control	NOUN
fnp-3679	145	12	(	(	PUNCT
fnp-3679	145	13	fig	fig	NOUN
fnp-3679	145	14	.	.	PUNCT
fnp-3679	146	1	2	2	NUM
fnp-3679	146	2	,	,	PUNCT
fnp-3679	146	3	left	left	ADJ
fnp-3679	146	4	panel	panel	NOUN
fnp-3679	146	5	,	,	PUNCT
fnp-3679	146	6	subject	subject	ADJ
fnp-3679	146	7	f,62	f,62	NOUN
fnp-3679	146	8	)	)	PUNCT
fnp-3679	146	9	.	.	PUNCT
fnp-3679	147	1	figure	figure	NOUN
fnp-3679	147	2	2	2	NUM
fnp-3679	147	3	.	.	PUNCT
fnp-3679	147	4	western	western	ADJ
fnp-3679	147	5	blot	blot	NOUN
fnp-3679	147	6	of	of	ADP
fnp-3679	147	7	desmin	desmin	NOUN
fnp-3679	147	8	and	and	CCONJ
fnp-3679	147	9	frataxin	frataxin	NOUN
fnp-3679	147	10	in	in	ADP
fnp-3679	147	11	6	6	NUM
fnp-3679	147	12	pooled	pool	VERB
fnp-3679	147	13	fa	fa	NOUN
fnp-3679	147	14	heart	heart	NOUN
fnp-3679	147	15	lysates	lysate	NOUN
fnp-3679	147	16	and	and	CCONJ
fnp-3679	147	17	mass	mass	ADJ
fnp-3679	147	18	spectrometry	spectrometry	NOUN
fnp-3679	147	19	of	of	ADP
fnp-3679	147	20	a	a	DET
fnp-3679	147	21	proteolytic	proteolytic	ADJ
fnp-3679	147	22	desmin	desmin	NOUN
fnp-3679	147	23	fragment	fragment	NOUN
fnp-3679	147	24	.	.	PUNCT
fnp-3679	148	1	lane	lane	NOUN
fnp-3679	148	2	1	1	NUM
fnp-3679	148	3	:	:	PUNCT
fnp-3679	148	4	prestained	prestaine	VERB
fnp-3679	148	5	proteins	protein	NOUN
fnp-3679	148	6	of	of	ADP
fnp-3679	148	7	known	know	VERB
fnp-3679	148	8	mass	mass	PROPN
fnp-3679	148	9	.	.	PUNCT
fnp-3679	149	1	lane	lane	PROPN
fnp-3679	149	2	2	2	NUM
fnp-3679	149	3	:	:	PUNCT
fnp-3679	149	4	western	western	ADJ
fnp-3679	149	5	blot	blot	NOUN
fnp-3679	149	6	of	of	ADP
fnp-3679	149	7	frataxin	frataxin	NOUN
fnp-3679	149	8	(	(	PUNCT
fnp-3679	149	9	fxn	fxn	NOUN
fnp-3679	149	10	)	)	PUNCT
fnp-3679	149	11	.	.	PUNCT
fnp-3679	150	1	pooling	pool	VERB
fnp-3679	150	2	of	of	ADP
fnp-3679	150	3	heart	heart	NOUN
fnp-3679	150	4	lysates	lysate	NOUN
fnp-3679	150	5	allows	allow	VERB
fnp-3679	150	6	the	the	DET
fnp-3679	150	7	detection	detection	NOUN
fnp-3679	150	8	of	of	ADP
fnp-3679	150	9	residual	residual	ADJ
fnp-3679	150	10	frataxin	frataxin	NOUN
fnp-3679	150	11	in	in	ADP
fnp-3679	150	12	fa	fa	PROPN
fnp-3679	150	13	.	.	PUNCT
fnp-3679	150	14	lane	lane	PROPN
fnp-3679	150	15	3	3	NUM
fnp-3679	150	16	:	:	PUNCT
fnp-3679	150	17	western	western	ADJ
fnp-3679	150	18	blot	blot	NOUN
fnp-3679	150	19	of	of	ADP
fnp-3679	150	20	desmin	desmin	NOUN
fnp-3679	150	21	.	.	PUNCT
fnp-3679	151	1	the	the	DET
fnp-3679	151	2	canonical	canonical	ADJ
fnp-3679	151	3	desmin	desmin	NOUN
fnp-3679	151	4	migrates	migrate	VERB
fnp-3679	151	5	at	at	ADP
fnp-3679	151	6	53	53	NUM
fnp-3679	151	7	kda	kda	NOUN
fnp-3679	151	8	(	(	PUNCT
fnp-3679	151	9	des	des	PROPN
fnp-3679	151	10	)	)	PUNCT
fnp-3679	151	11	,	,	PUNCT
fnp-3679	151	12	but	but	CCONJ
fnp-3679	151	13	a	a	DET
fnp-3679	151	14	second	second	ADJ
fnp-3679	151	15	,	,	PUNCT
fnp-3679	151	16	strongly	strongly	ADV
fnp-3679	151	17	reactive	reactive	ADJ
fnp-3679	151	18	desmin	desmin	ADJ
fnp-3679	151	19	band	band	NOUN
fnp-3679	151	20	(	(	PUNCT
fnp-3679	151	21	arrow	arrow	NOUN
fnp-3679	151	22	)	)	PUNCT
fnp-3679	151	23	is	be	AUX
fnp-3679	151	24	located	locate	VERB
fnp-3679	151	25	at	at	ADP
fnp-3679	151	26	approximately	approximately	ADV
fnp-3679	151	27	45	45	NUM
fnp-3679	151	28	kda	kda	NOUN
fnp-3679	151	29	.	.	PUNCT
fnp-3679	152	1	lane	lane	PROPN
fnp-3679	152	2	4	4	NUM
fnp-3679	152	3	:	:	PUNCT
fnp-3679	152	4	mass	mass	ADJ
fnp-3679	152	5	spectrometry	spectrometry	NOUN
fnp-3679	152	6	of	of	ADP
fnp-3679	152	7	the	the	DET
fnp-3679	152	8	truncated	truncated	ADJ
fnp-3679	152	9	desmin	desmin	NOUN
fnp-3679	152	10	fragment	fragment	NOUN
fnp-3679	152	11	in	in	ADP
fnp-3679	152	12	lane	lane	PROPN
fnp-3679	152	13	3	3	NUM
fnp-3679	152	14	(	(	PUNCT
fnp-3679	152	15	arrow	arrow	NOUN
fnp-3679	152	16	)	)	PUNCT
fnp-3679	152	17	.	.	PUNCT
fnp-3679	153	1	the	the	DET
fnp-3679	153	2	amino	amino	NOUN
fnp-3679	153	3	acids	acid	NOUN
fnp-3679	153	4	in	in	ADP
fnp-3679	153	5	red	red	ADJ
fnp-3679	153	6	were	be	AUX
fnp-3679	153	7	identified	identify	VERB
fnp-3679	153	8	by	by	ADP
fnp-3679	153	9	liquid	liquid	ADJ
fnp-3679	153	10	chromatography	chromatography	NOUN
fnp-3679	153	11	-	-	PUNCT
fnp-3679	153	12	tandem	tandem	NOUN
fnp-3679	153	13	mass	mass	PROPN
fnp-3679	153	14	spectrometry	spectrometry	NOUN
fnp-3679	153	15	.	.	PUNCT
fnp-3679	154	1	the	the	DET
fnp-3679	154	2	sequences	sequence	NOUN
fnp-3679	154	3	represent	represent	VERB
fnp-3679	154	4	signature	signature	NOUN
fnp-3679	154	5	peptides	peptide	NOUN
fnp-3679	154	6	of	of	ADP
fnp-3679	154	7	desmin	desmin	ADJ
fnp-3679	154	8	.	.	PUNCT
fnp-3679	155	1	figure	figure	NOUN
fnp-3679	155	2	3	3	NUM
fnp-3679	155	3	.	.	PUNCT
fnp-3679	155	4	western	western	ADJ
fnp-3679	155	5	blots	blot	NOUN
fnp-3679	155	6	of	of	ADP
fnp-3679	155	7	desmin	desmin	NOUN
fnp-3679	155	8	in	in	ADP
fnp-3679	155	9	6	6	NUM
fnp-3679	155	10	normal	normal	ADJ
fnp-3679	155	11	control	control	NOUN
fnp-3679	155	12	and	and	CCONJ
fnp-3679	155	13	12	12	NUM
fnp-3679	155	14	fa	fa	NOUN
fnp-3679	155	15	heart	heart	NOUN
fnp-3679	155	16	lysates	lysate	NOUN
fnp-3679	155	17	.	.	PUNCT
fnp-3679	156	1	all	all	DET
fnp-3679	156	2	wells	well	NOUN
fnp-3679	156	3	received	receive	VERB
fnp-3679	156	4	a	a	DET
fnp-3679	156	5	total	total	ADJ
fnp-3679	156	6	protein	protein	NOUN
fnp-3679	156	7	load	load	NOUN
fnp-3679	156	8	of	of	ADP
fnp-3679	156	9	50	50	NUM
fnp-3679	156	10	µg	µg	NOUN
fnp-3679	156	11	.	.	PUNCT
fnp-3679	157	1	the	the	DET
fnp-3679	157	2	arrows	arrow	NOUN
fnp-3679	157	3	show	show	VERB
fnp-3679	157	4	the	the	DET
fnp-3679	157	5	location	location	NOUN
fnp-3679	157	6	of	of	ADP
fnp-3679	157	7	canonical	canonical	ADJ
fnp-3679	157	8	desmin	desmin	NOUN
fnp-3679	157	9	at	at	ADP
fnp-3679	157	10	53	53	NUM
fnp-3679	157	11	kda	kda	NOUN
fnp-3679	157	12	,	,	PUNCT
fnp-3679	157	13	a	a	DET
fnp-3679	157	14	desmin	desmin	ADJ
fnp-3679	157	15	fragment	fragment	NOUN
fnp-3679	157	16	,	,	PUNCT
fnp-3679	157	17	and	and	CCONJ
fnp-3679	157	18	gapdh	gapdh	NOUN
fnp-3679	157	19	(	(	PUNCT
fnp-3679	157	20	as	as	ADP
fnp-3679	157	21	a	a	DET
fnp-3679	157	22	loading	loading	NOUN
fnp-3679	157	23	control	control	NOUN
fnp-3679	157	24	)	)	PUNCT
fnp-3679	157	25	.	.	PUNCT
fnp-3679	158	1	the	the	DET
fnp-3679	158	2	pvdf	pvdf	PROPN
fnp-3679	158	3	membranes	membrane	NOUN
fnp-3679	158	4	were	be	AUX
fnp-3679	158	5	cut	cut	VERB
fnp-3679	158	6	horizontally	horizontally	ADV
fnp-3679	158	7	to	to	PART
fnp-3679	158	8	generate	generate	VERB
fnp-3679	158	9	two	two	NUM
fnp-3679	158	10	segments	segment	NOUN
fnp-3679	158	11	of	of	ADP
fnp-3679	158	12	the	the	DET
fnp-3679	158	13	blot	blot	NOUN
fnp-3679	158	14	and	and	CCONJ
fnp-3679	158	15	allow	allow	VERB
fnp-3679	158	16	visualization	visualization	NOUN
fnp-3679	158	17	of	of	ADP
fnp-3679	158	18	gapdh	gapdh	NOUN
fnp-3679	158	19	.	.	PUNCT
fnp-3679	159	1	sex	sex	NOUN
fnp-3679	159	2	and	and	CCONJ
fnp-3679	159	3	ages	age	NOUN
fnp-3679	159	4	are	be	AUX
fnp-3679	159	5	shown	show	VERB
fnp-3679	159	6	for	for	ADP
fnp-3679	159	7	the	the	DET
fnp-3679	159	8	lanes	lane	NOUN
fnp-3679	159	9	of	of	ADP
fnp-3679	159	10	control	control	NOUN
fnp-3679	159	11	lysates	lysate	NOUN
fnp-3679	159	12	(	(	PUNCT
fnp-3679	159	13	left	left	ADV
fnp-3679	159	14	)	)	PUNCT
fnp-3679	159	15	;	;	PUNCT
fnp-3679	159	16	in	in	ADP
fnp-3679	159	17	the	the	DET
fnp-3679	159	18	right	right	ADJ
fnp-3679	159	19	panel	panel	NOUN
fnp-3679	159	20	,	,	PUNCT
fnp-3679	159	21	of	of	ADP
fnp-3679	159	22	fa	fa	PROPN
fnp-3679	159	23	lysates	lysate	NOUN
fnp-3679	159	24	,	,	PUNCT
fnp-3679	159	25	the	the	DET
fnp-3679	159	26	entries	entry	NOUN
fnp-3679	159	27	include	include	VERB
fnp-3679	159	28	sex	sex	NOUN
fnp-3679	159	29	,	,	PUNCT
fnp-3679	159	30	age	age	NOUN
fnp-3679	159	31	,	,	PUNCT
fnp-3679	159	32	and	and	CCONJ
fnp-3679	159	33	gaa	gaa	PROPN
fnp-3679	159	34	trinucleotide	trinucleotide	NOUN
fnp-3679	159	35	repeats	repeat	NOUN
fnp-3679	159	36	.	.	PUNCT
fnp-3679	160	1	in	in	ADP
fnp-3679	160	2	8	8	NUM
fnp-3679	160	3	of	of	ADP
fnp-3679	160	4	12	12	NUM
fnp-3679	160	5	fa	fa	NOUN
fnp-3679	160	6	lysates	lysate	NOUN
fnp-3679	160	7	,	,	PUNCT
fnp-3679	160	8	the	the	DET
fnp-3679	160	9	blots	blot	NOUN
fnp-3679	160	10	show	show	VERB
fnp-3679	160	11	prominent	prominent	ADJ
fnp-3679	160	12	expression	expression	NOUN
fnp-3679	160	13	of	of	ADP
fnp-3679	160	14	a	a	DET
fnp-3679	160	15	proteolytic	proteolytic	ADJ
fnp-3679	160	16	desmin	desmin	ADJ
fnp-3679	160	17	fragments	fragment	NOUN
fnp-3679	160	18	at	at	ADP
fnp-3679	160	19	approximately	approximately	ADV
fnp-3679	160	20	45	45	NUM
fnp-3679	160	21	kda	kda	NOUN
fnp-3679	160	22	.	.	PUNCT
fnp-3679	161	1	figure	figure	NOUN
fnp-3679	161	2	4	4	NUM
fnp-3679	161	3	.	.	PUNCT
fnp-3679	162	1	desmin	desmin	ADJ
fnp-3679	162	2	co	co	NOUN
fnp-3679	162	3	-	-	NOUN
fnp-3679	162	4	immunoprecipitation	immunoprecipitation	NOUN
fnp-3679	162	5	.	.	PUNCT
fnp-3679	163	1	desmin	desmin	ADJ
fnp-3679	163	2	in	in	ADP
fnp-3679	163	3	pooled	pooled	ADJ
fnp-3679	163	4	lysates	lysate	NOUN
fnp-3679	163	5	of	of	ADP
fnp-3679	163	6	6	6	NUM
fnp-3679	163	7	fa	fa	NOUN
fnp-3679	163	8	hearts	heart	NOUN
fnp-3679	163	9	was	be	AUX
fnp-3679	163	10	precipitated	precipitate	VERB
fnp-3679	163	11	by	by	ADP
fnp-3679	163	12	anti	anti	ADJ
fnp-3679	163	13	-	-	ADJ
fnp-3679	163	14	desmin	desmin	ADJ
fnp-3679	163	15	,	,	PUNCT
fnp-3679	163	16	and	and	CCONJ
fnp-3679	163	17	the	the	DET
fnp-3679	163	18	protein	protein	NOUN
fnp-3679	163	19	-	-	PUNCT
fnp-3679	163	20	antibody	antibody	NOUN
fnp-3679	163	21	complex	complex	NOUN
fnp-3679	163	22	was	be	AUX
fnp-3679	163	23	recovered	recover	VERB
fnp-3679	163	24	on	on	ADP
fnp-3679	163	25	protein	protein	NOUN
fnp-3679	163	26	a	a	DET
fnp-3679	163	27	sepharose	sepharose	NOUN
fnp-3679	163	28	.	.	PUNCT
fnp-3679	164	1	desmin	desmin	ADJ
fnp-3679	164	2	and	and	CCONJ
fnp-3679	164	3	other	other	ADJ
fnp-3679	164	4	proteins	protein	NOUN
fnp-3679	164	5	were	be	AUX
fnp-3679	164	6	released	release	VERB
fnp-3679	164	7	from	from	ADP
fnp-3679	164	8	protein	protein	NOUN
fnp-3679	164	9	a	a	NOUN
fnp-3679	164	10	by	by	ADP
fnp-3679	164	11	heating	heat	VERB
fnp-3679	164	12	in	in	ADP
fnp-3679	164	13	laemmli	laemmli	NOUN
fnp-3679	164	14	’s	’s	PART
fnp-3679	164	15	sample	sample	NOUN
fnp-3679	164	16	buffer	buffer	NOUN
fnp-3679	164	17	containing	contain	VERB
fnp-3679	164	18	β	β	NOUN
fnp-3679	164	19	-	-	NOUN
fnp-3679	164	20	mercaptoethanol	mercaptoethanol	NOUN
fnp-3679	164	21	.	.	PUNCT
fnp-3679	165	1	aliquots	aliquot	NOUN
fnp-3679	165	2	were	be	AUX
fnp-3679	165	3	electrophoresed	electrophorese	VERB
fnp-3679	165	4	by	by	ADP
fnp-3679	165	5	sds	sds	PROPN
fnp-3679	165	6	-	-	PUNCT
fnp-3679	165	7	page	page	NOUN
fnp-3679	165	8	,	,	PUNCT
fnp-3679	165	9	electroblotted	electroblotte	VERB
fnp-3679	165	10	onto	onto	ADP
fnp-3679	165	11	pvdf	pvdf	PROPN
fnp-3679	165	12	membranes	membrane	NOUN
fnp-3679	165	13	,	,	PUNCT
fnp-3679	165	14	and	and	CCONJ
fnp-3679	165	15	visualized	visualize	VERB
fnp-3679	165	16	by	by	ADP
fnp-3679	165	17	immunochemistry	immunochemistry	NOUN
fnp-3679	165	18	with	with	ADP
fnp-3679	165	19	antibodies	antibody	NOUN
fnp-3679	165	20	to	to	ADP
fnp-3679	165	21	the	the	DET
fnp-3679	165	22	stated	state	VERB
fnp-3679	165	23	proteins	protein	NOUN
fnp-3679	165	24	.	.	PUNCT
fnp-3679	166	1	the	the	DET
fnp-3679	166	2	western	western	ADJ
fnp-3679	166	3	blot	blot	NOUN
fnp-3679	166	4	shows	show	VERB
fnp-3679	166	5	desmin	desmin	ADJ
fnp-3679	166	6	bands	band	NOUN
fnp-3679	166	7	at	at	ADP
fnp-3679	166	8	approximately	approximately	ADV
fnp-3679	166	9	53	53	NUM
fnp-3679	166	10	kda	kda	NOUN
fnp-3679	166	11	and	and	CCONJ
fnp-3679	166	12	between	between	ADP
fnp-3679	166	13	40	40	NUM
fnp-3679	166	14	and	and	CCONJ
fnp-3679	166	15	45	45	NUM
fnp-3679	166	16	kda	kda	NOUN
fnp-3679	166	17	,	,	PUNCT
fnp-3679	166	18	respectively	respectively	ADV
fnp-3679	166	19	.	.	PUNCT
fnp-3679	167	1	a	a	DET
fnp-3679	167	2	distinct	distinct	ADJ
fnp-3679	167	3	band	band	NOUN
fnp-3679	167	4	of	of	ADP
fnp-3679	167	5	αb	αb	PROPN
fnp-3679	167	6	-	-	PUNCT
fnp-3679	167	7	crystallin	crystallin	NOUN
fnp-3679	167	8	is	be	AUX
fnp-3679	167	9	also	also	ADV
fnp-3679	167	10	present	present	ADJ
fnp-3679	167	11	.	.	PUNCT
fnp-3679	168	1	other	other	ADJ
fnp-3679	168	2	lighter	light	ADJ
fnp-3679	168	3	bands	band	NOUN
fnp-3679	168	4	at	at	ADP
fnp-3679	168	5	45	45	NUM
fnp-3679	168	6	kda	kda	NOUN
fnp-3679	168	7	,	,	PUNCT
fnp-3679	168	8	25	25	NUM
fnp-3679	168	9	kda	kda	NOUN
fnp-3679	168	10	and	and	CCONJ
fnp-3679	168	11	15	15	NUM
fnp-3679	168	12	kda	kda	NOUN
fnp-3679	168	13	are	be	AUX
fnp-3679	168	14	considered	consider	VERB
fnp-3679	168	15	preparative	preparative	ADJ
fnp-3679	168	16	artifacts	artifact	NOUN
fnp-3679	168	17	.	.	PUNCT
fnp-3679	169	1	immunohistochemistry	immunohistochemistry	NOUN
fnp-3679	169	2	:	:	PUNCT
fnp-3679	169	3	in	in	ADP
fnp-3679	169	4	normal	normal	ADJ
fnp-3679	169	5	hearts	heart	NOUN
fnp-3679	169	6	,	,	PUNCT
fnp-3679	169	7	antibodies	antibodie	VERB
fnp-3679	169	8	to	to	PART
fnp-3679	169	9	desmin	desmin	VERB
fnp-3679	169	10	and	and	CCONJ
fnp-3679	169	11	αb	αb	NOUN
fnp-3679	169	12	-	-	PUNCT
fnp-3679	169	13	crystallin	crystallin	NOUN
fnp-3679	169	14	revealed	reveal	VERB
fnp-3679	169	15	reaction	reaction	NOUN
fnp-3679	169	16	product	product	NOUN
fnp-3679	169	17	in	in	ADP
fnp-3679	169	18	intercalated	intercalated	ADJ
fnp-3679	169	19	discs	disc	NOUN
fnp-3679	169	20	and	and	CCONJ
fnp-3679	169	21	z	z	NOUN
fnp-3679	169	22	-	-	PUNCT
fnp-3679	169	23	discs	disc	NOUN
fnp-3679	169	24	.	.	PUNCT
fnp-3679	170	1	anti	anti	ADJ
fnp-3679	170	2	-	-	ADJ
fnp-3679	170	3	αb	αb	NOUN
fnp-3679	170	4	-	-	PUNCT
fnp-3679	170	5	crystallin	crystallin	NOUN
fnp-3679	170	6	also	also	ADV
fnp-3679	170	7	showed	show	VERB
fnp-3679	170	8	m	m	PRON
fnp-3679	170	9	bands	band	NOUN
fnp-3679	170	10	on	on	ADP
fnp-3679	170	11	longitudinal	longitudinal	ADJ
fnp-3679	170	12	sections	section	NOUN
fnp-3679	170	13	of	of	ADP
fnp-3679	170	14	heart	heart	NOUN
fnp-3679	170	15	fibers	fiber	NOUN
fnp-3679	170	16	that	that	PRON
fnp-3679	170	17	were	be	AUX
fnp-3679	170	18	desmin	desmin	ADJ
fnp-3679	170	19	negative	negative	ADJ
fnp-3679	170	20	(	(	PUNCT
fnp-3679	170	21	fig	fig	NOUN
fnp-3679	170	22	.	.	PUNCT
fnp-3679	170	23	5f	5f	NOUN
fnp-3679	170	24	)	)	PUNCT
fnp-3679	170	25	.	.	PUNCT
fnp-3679	171	1	in	in	ADP
fnp-3679	171	2	fa	fa	PROPN
fnp-3679	171	3	,	,	PUNCT
fnp-3679	171	4	desmin	desmin	ADJ
fnp-3679	171	5	and	and	CCONJ
fnp-3679	171	6	αb	αb	PROPN
fnp-3679	171	7	-	-	PUNCT
fnp-3679	171	8	crystallin	crystallin	NOUN
fnp-3679	171	9	reaction	reaction	NOUN
fnp-3679	171	10	product	product	NOUN
fnp-3679	171	11	showed	show	VERB
fnp-3679	171	12	abnormally	abnormally	ADV
fnp-3679	171	13	wide	wide	ADV
fnp-3679	171	14	,	,	PUNCT
fnp-3679	171	15	thickened	thicken	VERB
fnp-3679	171	16	,	,	PUNCT
fnp-3679	171	17	and	and	CCONJ
fnp-3679	171	18	hyperconvoluted	hyperconvolute	VERB
fnp-3679	171	19	intercalated	intercalated	ADJ
fnp-3679	171	20	discs	disc	NOUN
fnp-3679	171	21	and	and	CCONJ
fnp-3679	171	22	aggregates	aggregate	NOUN
fnp-3679	171	23	in	in	ADP
fnp-3679	171	24	the	the	DET
fnp-3679	171	25	sarcoplasm	sarcoplasm	PROPN
fnp-3679	171	26	(	(	PUNCT
fnp-3679	171	27	fig	fig	NOUN
fnp-3679	171	28	.	.	PUNCT
fnp-3679	172	1	5	5	NUM
fnp-3679	172	2	)	)	PUNCT
fnp-3679	172	3	.	.	PUNCT
fnp-3679	173	1	desmin	desmin	ADJ
fnp-3679	173	2	and	and	CCONJ
fnp-3679	173	3	αb	αb	NOUN
fnp-3679	173	4	-	-	PUNCT
fnp-3679	173	5	crystallin	crystallin	NOUN
fnp-3679	173	6	reaction	reaction	NOUN
fnp-3679	173	7	product	product	NOUN
fnp-3679	173	8	in	in	ADP
fnp-3679	173	9	the	the	DET
fnp-3679	173	10	two	two	NUM
fnp-3679	173	11	compound	compound	NOUN
fnp-3679	173	12	heterozygous	heterozygous	ADJ
fnp-3679	173	13	fa	fa	NOUN
fnp-3679	173	14	cases	case	NOUN
fnp-3679	173	15	showed	show	VERB
fnp-3679	173	16	a	a	DET
fnp-3679	173	17	similar	similar	ADJ
fnp-3679	173	18	degree	degree	NOUN
fnp-3679	173	19	of	of	ADP
fnp-3679	173	20	protein	protein	NOUN
fnp-3679	173	21	aggregate	aggregate	ADJ
fnp-3679	173	22	myopathy	myopathy	ADJ
fnp-3679	173	23	.	.	PUNCT
fnp-3679	174	1	reaction	reaction	NOUN
fnp-3679	174	2	product	product	NOUN
fnp-3679	174	3	for	for	ADP
fnp-3679	174	4	β	β	NOUN
fnp-3679	174	5	-	-	NOUN
fnp-3679	174	6	spectrin	spectrin	ADJ
fnp-3679	174	7	,	,	PUNCT
fnp-3679	174	8	ankyrin	ankyrin	ADJ
fnp-3679	174	9	,	,	PUNCT
fnp-3679	174	10	plectin	plectin	NOUN
fnp-3679	174	11	,	,	PUNCT
fnp-3679	174	12	and	and	CCONJ
fnp-3679	174	13	zasp	zasp	NOUN
fnp-3679	174	14	(	(	PUNCT
fnp-3679	174	15	cypher	cypher	PROPN
fnp-3679	174	16	)	)	PUNCT
fnp-3679	174	17	was	be	AUX
fnp-3679	174	18	less	less	ADV
fnp-3679	174	19	informative	informative	ADJ
fnp-3679	174	20	,	,	PUNCT
fnp-3679	174	21	though	though	SCONJ
fnp-3679	174	22	α	α	X
fnp-3679	174	23	-	-	PUNCT
fnp-3679	174	24	spectrin	spectrin	NOUN
fnp-3679	174	25	immunohistochemistry	immunohistochemistry	NOUN
fnp-3679	174	26	displayed	display	VERB
fnp-3679	174	27	the	the	DET
fnp-3679	174	28	chaotic	chaotic	ADJ
fnp-3679	174	29	disorganization	disorganization	NOUN
fnp-3679	174	30	of	of	ADP
fnp-3679	174	31	intercalated	intercalated	ADJ
fnp-3679	174	32	discs	disc	NOUN
fnp-3679	174	33	.	.	PUNCT
fnp-3679	175	1	α	α	X
fnp-3679	175	2	-	-	PUNCT
fnp-3679	175	3	actinin	actinin	NOUN
fnp-3679	175	4	reaction	reaction	NOUN
fnp-3679	175	5	product	product	NOUN
fnp-3679	175	6	showed	show	VERB
fnp-3679	175	7	the	the	DET
fnp-3679	175	8	striation	striation	NOUN
fnp-3679	175	9	of	of	ADP
fnp-3679	175	10	cardiomyocytes	cardiomyocyte	NOUN
fnp-3679	175	11	by	by	ADP
fnp-3679	175	12	reacting	react	VERB
fnp-3679	175	13	with	with	ADP
fnp-3679	175	14	z	z	NOUN
fnp-3679	175	15	-	-	PUNCT
fnp-3679	175	16	discs	disc	NOUN
fnp-3679	175	17	but	but	CCONJ
fnp-3679	175	18	was	be	AUX
fnp-3679	175	19	not	not	PART
fnp-3679	175	20	useful	useful	ADJ
fnp-3679	175	21	to	to	PART
fnp-3679	175	22	assess	assess	VERB
fnp-3679	175	23	the	the	DET
fnp-3679	175	24	state	state	NOUN
fnp-3679	175	25	of	of	ADP
fnp-3679	175	26	intercalated	intercalated	ADJ
fnp-3679	175	27	discs	disc	NOUN
fnp-3679	175	28	.	.	PUNCT
fnp-3679	176	1	figure	figure	NOUN
fnp-3679	176	2	5	5	NUM
fnp-3679	176	3	.	.	PUNCT
fnp-3679	176	4	immunohistochemistry	immunohistochemistry	NOUN
fnp-3679	176	5	of	of	ADP
fnp-3679	176	6	desmin	desmin	PROPN
fnp-3679	176	7	and	and	CCONJ
fnp-3679	176	8	αb	αb	NOUN
fnp-3679	176	9	-	-	NOUN
fnp-3679	176	10	crystallin	crystallin	NOUN
fnp-3679	176	11	in	in	ADP
fnp-3679	176	12	left	left	ADJ
fnp-3679	176	13	ventricular	ventricular	ADJ
fnp-3679	176	14	wall	wall	NOUN
fnp-3679	176	15	.	.	PUNCT
fnp-3679	177	1	a	a	DET
fnp-3679	177	2	-	-	PUNCT
fnp-3679	177	3	b	b	NOUN
fnp-3679	177	4	,	,	PUNCT
fnp-3679	177	5	desmin	desmin	ADJ
fnp-3679	177	6	;	;	PUNCT
fnp-3679	177	7	c	c	X
fnp-3679	177	8	-	-	SYM
fnp-3679	177	9	f	f	NOUN
fnp-3679	177	10	,	,	PUNCT
fnp-3679	177	11	αb	αb	PROPN
fnp-3679	177	12	-	-	PUNCT
fnp-3679	177	13	crystallin	crystallin	NOUN
fnp-3679	177	14	.	.	PUNCT
fnp-3679	178	1	a	a	DET
fnp-3679	178	2	and	and	CCONJ
fnp-3679	178	3	c	c	NOUN
fnp-3679	178	4	,	,	PUNCT
fnp-3679	178	5	normal	normal	ADJ
fnp-3679	178	6	left	leave	VERB
fnp-3679	178	7	ventricular	ventricular	ADJ
fnp-3679	178	8	wall	wall	NOUN
fnp-3679	178	9	;	;	PUNCT
fnp-3679	178	10	b	b	X
fnp-3679	178	11	,	,	PUNCT
fnp-3679	178	12	d	d	PROPN
fnp-3679	178	13	-	-	PUNCT
fnp-3679	178	14	f	f	PROPN
fnp-3679	178	15	,	,	PUNCT
fnp-3679	178	16	fa	fa	PROPN
fnp-3679	178	17	.	.	PUNCT
fnp-3679	178	18	in	in	ADP
fnp-3679	178	19	normal	normal	ADJ
fnp-3679	178	20	myocardium	myocardium	NOUN
fnp-3679	178	21	,	,	PUNCT
fnp-3679	178	22	desmin	desmin	ADJ
fnp-3679	178	23	(	(	PUNCT
fnp-3679	178	24	a	a	NOUN
fnp-3679	178	25	)	)	PUNCT
fnp-3679	178	26	and	and	CCONJ
fnp-3679	178	27	αb	αb	NOUN
fnp-3679	178	28	-	-	PUNCT
fnp-3679	178	29	crystallin	crystallin	NOUN
fnp-3679	178	30	(	(	PUNCT
fnp-3679	178	31	c	c	NOUN
fnp-3679	178	32	)	)	PUNCT
fnp-3679	178	33	are	be	AUX
fnp-3679	178	34	localized	localize	VERB
fnp-3679	178	35	in	in	ADP
fnp-3679	178	36	intercalated	intercalated	ADJ
fnp-3679	178	37	and	and	CCONJ
fnp-3679	178	38	z	z	NOUN
fnp-3679	178	39	discs	disc	NOUN
fnp-3679	178	40	.	.	PUNCT
fnp-3679	179	1	in	in	ADP
fnp-3679	179	2	fa	fa	PROPN
fnp-3679	179	3	,	,	PUNCT
fnp-3679	179	4	desmin	desmin	ADJ
fnp-3679	179	5	reaction	reaction	NOUN
fnp-3679	179	6	product	product	NOUN
fnp-3679	179	7	reveals	reveal	VERB
fnp-3679	179	8	accumulation	accumulation	NOUN
fnp-3679	179	9	in	in	ADP
fnp-3679	179	10	or	or	CCONJ
fnp-3679	179	11	near	near	ADP
fnp-3679	179	12	disorganized	disorganized	ADJ
fnp-3679	179	13	intercalated	intercalated	ADJ
fnp-3679	179	14	discs	disc	NOUN
fnp-3679	179	15	(	(	PUNCT
fnp-3679	179	16	b	b	NOUN
fnp-3679	179	17	,	,	PUNCT
fnp-3679	179	18	arrow	arrow	NOUN
fnp-3679	179	19	)	)	PUNCT
fnp-3679	179	20	.	.	PUNCT
fnp-3679	180	1	αb	αb	PROPN
fnp-3679	180	2	-	-	PUNCT
fnp-3679	180	3	crystallin	crystallin	PROPN
fnp-3679	180	4	immunohistochemistry	immunohistochemistry	PROPN
fnp-3679	180	5	shows	show	VERB
fnp-3679	180	6	wide	wide	ADJ
fnp-3679	180	7	and	and	CCONJ
fnp-3679	180	8	fragmented	fragmented	ADJ
fnp-3679	180	9	intercalated	intercalated	ADJ
fnp-3679	180	10	discs	disc	NOUN
fnp-3679	180	11	(	(	PUNCT
fnp-3679	180	12	d	d	NOUN
fnp-3679	180	13	and	and	CCONJ
fnp-3679	180	14	e	e	NOUN
fnp-3679	180	15	)	)	PUNCT
fnp-3679	180	16	.	.	PUNCT
fnp-3679	181	1	enlargement	enlargement	NOUN
fnp-3679	181	2	of	of	ADP
fnp-3679	181	3	the	the	DET
fnp-3679	181	4	square	square	NOUN
fnp-3679	181	5	in	in	ADP
fnp-3679	181	6	e	e	NOUN
fnp-3679	181	7	displays	display	VERB
fnp-3679	181	8	αb	αb	PROPN
fnp-3679	181	9	-	-	PUNCT
fnp-3679	181	10	crystallin	crystallin	NOUN
fnp-3679	181	11	reaction	reaction	NOUN
fnp-3679	181	12	product	product	NOUN
fnp-3679	181	13	in	in	ADP
fnp-3679	181	14	m	m	PROPN
fnp-3679	181	15	bands	band	NOUN
fnp-3679	181	16	(	(	PUNCT
fnp-3679	181	17	f	f	X
fnp-3679	181	18	,	,	PUNCT
fnp-3679	181	19	arrow	arrow	NOUN
fnp-3679	181	20	,	,	PUNCT
fnp-3679	181	21	m	m	PROPN
fnp-3679	181	22	)	)	PUNCT
fnp-3679	181	23	.	.	PUNCT
fnp-3679	182	1	m	m	PROPN
fnp-3679	182	2	bands	band	NOUN
fnp-3679	182	3	are	be	AUX
fnp-3679	182	4	desmin	desmin	ADJ
fnp-3679	182	5	-	-	PUNCT
fnp-3679	182	6	negative	negative	ADJ
fnp-3679	182	7	.	.	PUNCT
fnp-3679	183	1	bars	bar	NOUN
fnp-3679	183	2	;	;	PUNCT
fnp-3679	183	3	a	a	DET
fnp-3679	183	4	-	-	PUNCT
fnp-3679	183	5	e	e	NOUN
fnp-3679	183	6	,	,	PUNCT
fnp-3679	183	7	10	10	NUM
fnp-3679	183	8	µm	µm	NOUN
fnp-3679	183	9	;	;	PUNCT
fnp-3679	183	10	f	f	X
fnp-3679	183	11	,	,	PUNCT
fnp-3679	183	12	3	3	NUM
fnp-3679	183	13	µm	µm	NOUN
fnp-3679	183	14	.	.	PUNCT
fnp-3679	183	15	fa	fa	PROPN
fnp-3679	183	16	patients	patient	NOUN
fnp-3679	183	17	:	:	PUNCT
fnp-3679	184	1	b	b	X
fnp-3679	184	2	,	,	PUNCT
fnp-3679	184	3	f	f	PROPN
fnp-3679	184	4	,	,	PUNCT
fnp-3679	184	5	67	67	NUM
fnp-3679	184	6	gaa	gaa	PROPN
fnp-3679	184	7	621/766	621/766	NUM
fnp-3679	184	8	;	;	PUNCT
fnp-3679	184	9	d	d	X
fnp-3679	184	10	-	-	PUNCT
fnp-3679	184	11	f	f	PROPN
fnp-3679	184	12	,	,	PUNCT
fnp-3679	184	13	f	f	PROPN
fnp-3679	184	14	,	,	PUNCT
fnp-3679	184	15	69	69	NUM
fnp-3679	184	16	,	,	PUNCT
fnp-3679	184	17	gaa	gaa	PROPN
fnp-3679	185	1	560/560	560/560	PROPN
fnp-3679	185	2	.	.	PUNCT
fnp-3679	185	3	double	double	ADJ
fnp-3679	185	4	-	-	PUNCT
fnp-3679	185	5	label	label	NOUN
fnp-3679	185	6	laser	laser	NOUN
fnp-3679	185	7	scanning	scan	VERB
fnp-3679	185	8	confocal	confocal	ADJ
fnp-3679	185	9	immunofluorescence	immunofluorescence	NOUN
fnp-3679	185	10	:	:	PUNCT
fnp-3679	185	11	figure	figure	NOUN
fnp-3679	185	12	6	6	NUM
fnp-3679	185	13	shows	show	VERB
fnp-3679	185	14	the	the	DET
fnp-3679	185	15	colocalization	colocalization	NOUN
fnp-3679	185	16	of	of	ADP
fnp-3679	185	17	desmin	desmin	PROPN
fnp-3679	185	18	and	and	CCONJ
fnp-3679	185	19	αb	αb	NOUN
fnp-3679	185	20	-	-	NOUN
fnp-3679	185	21	crystallin	crystallin	NOUN
fnp-3679	185	22	in	in	ADP
fnp-3679	185	23	z	z	NOUN
fnp-3679	185	24	-	-	PUNCT
fnp-3679	185	25	discs	disc	NOUN
fnp-3679	185	26	and	and	CCONJ
fnp-3679	185	27	intercalated	intercalated	ADJ
fnp-3679	185	28	discs	disc	NOUN
fnp-3679	185	29	.	.	PUNCT
fnp-3679	186	1	in	in	ADP
fnp-3679	186	2	fa	fa	PROPN
fnp-3679	186	3	,	,	PUNCT
fnp-3679	186	4	intercalated	intercalated	ADJ
fnp-3679	186	5	discs	disc	NOUN
fnp-3679	186	6	are	be	AUX
fnp-3679	186	7	wider	wide	ADJ
fnp-3679	186	8	at	at	ADP
fnp-3679	186	9	approximately	approximately	ADV
fnp-3679	186	10	50	50	NUM
fnp-3679	186	11	µm	µm	NOUN
fnp-3679	186	12	than	than	ADP
fnp-3679	186	13	normal	normal	ADJ
fnp-3679	186	14	(	(	PUNCT
fnp-3679	186	15	approximately	approximately	ADV
fnp-3679	186	16	23	23	NUM
fnp-3679	186	17	µm	µm	NOUN
fnp-3679	186	18	)	)	PUNCT
fnp-3679	186	19	and	and	CCONJ
fnp-3679	186	20	have	have	AUX
fnp-3679	186	21	undergone	undergo	VERB
fnp-3679	186	22	chaotic	chaotic	ADJ
fnp-3679	186	23	disorganization	disorganization	NOUN
fnp-3679	186	24	(	(	PUNCT
fnp-3679	186	25	fig	fig	NOUN
fnp-3679	186	26	.	.	PUNCT
fnp-3679	187	1	6d	6d	NUM
fnp-3679	187	2	)	)	PUNCT
fnp-3679	187	3	.	.	PUNCT
fnp-3679	188	1	a	a	DET
fnp-3679	188	2	more	more	ADV
fnp-3679	188	3	advanced	advanced	ADJ
fnp-3679	188	4	fiber	fiber	NOUN
fnp-3679	188	5	destruction	destruction	NOUN
fnp-3679	188	6	is	be	AUX
fnp-3679	188	7	illustrated	illustrate	VERB
fnp-3679	188	8	in	in	ADP
fnp-3679	188	9	figure	figure	NOUN
fnp-3679	188	10	7	7	NUM
fnp-3679	188	11	.	.	PUNCT
fnp-3679	188	12	two	two	NUM
fnp-3679	188	13	adjacent	adjacent	ADJ
fnp-3679	188	14	fibers	fiber	NOUN
fnp-3679	188	15	display	display	VERB
fnp-3679	188	16	accumulation	accumulation	NOUN
fnp-3679	188	17	of	of	ADP
fnp-3679	188	18	desmin	desmin	PROPN
fnp-3679	188	19	and	and	CCONJ
fnp-3679	188	20	αb	αb	NOUN
fnp-3679	188	21	-	-	PUNCT
fnp-3679	188	22	crystallin	crystallin	NOUN
fnp-3679	188	23	,	,	PUNCT
fnp-3679	188	24	obliterating	obliterate	VERB
fnp-3679	188	25	the	the	DET
fnp-3679	188	26	contractile	contractile	NOUN
fnp-3679	188	27	apparatus	apparatus	NOUN
fnp-3679	188	28	of	of	ADP
fnp-3679	188	29	the	the	DET
fnp-3679	188	30	cardiomyocytes	cardiomyocyte	NOUN
fnp-3679	188	31	.	.	PUNCT
fnp-3679	189	1	a	a	DET
fnp-3679	189	2	search	search	NOUN
fnp-3679	189	3	for	for	ADP
fnp-3679	189	4	amyloid	amyloid	NOUN
fnp-3679	189	5	by	by	ADP
fnp-3679	189	6	polarizing	polarize	VERB
fnp-3679	189	7	light	light	NOUN
fnp-3679	189	8	for	for	ADP
fnp-3679	189	9	apple	apple	NOUN
fnp-3679	189	10	-	-	PUNCT
fnp-3679	189	11	green	green	NOUN
fnp-3679	189	12	birefringence	birefringence	NOUN
fnp-3679	189	13	and	and	CCONJ
fnp-3679	189	14	congo	congo	PROPN
fnp-3679	189	15	red	red	ADJ
fnp-3679	189	16	fluorescence	fluorescence	NOUN
fnp-3679	189	17	did	do	AUX
fnp-3679	189	18	not	not	PART
fnp-3679	189	19	reveal	reveal	VERB
fnp-3679	189	20	amyloid	amyloid	NOUN
fnp-3679	189	21	deposits	deposit	NOUN
fnp-3679	189	22	.	.	PUNCT
fnp-3679	190	1	figure	figure	VERB
fnp-3679	190	2	8	8	NUM
fnp-3679	190	3	shows	show	VERB
fnp-3679	190	4	double	double	ADJ
fnp-3679	190	5	-	-	PUNCT
fnp-3679	190	6	label	label	NOUN
fnp-3679	190	7	immunofluorescence	immunofluorescence	NOUN
fnp-3679	190	8	of	of	ADP
fnp-3679	190	9	desmin	desmin	NOUN
fnp-3679	190	10	and	and	CCONJ
fnp-3679	190	11	atp5b	atp5b	NUM
fnp-3679	190	12	.	.	PUNCT
fnp-3679	191	1	all	all	DET
fnp-3679	191	2	fibers	fiber	NOUN
fnp-3679	191	3	in	in	ADP
fnp-3679	191	4	fa	fa	NOUN
fnp-3679	191	5	contain	contain	VERB
fnp-3679	191	6	clusters	cluster	NOUN
fnp-3679	191	7	of	of	ADP
fnp-3679	191	8	mitochondria	mitochondria	NOUN
fnp-3679	191	9	,	,	PUNCT
fnp-3679	191	10	visualized	visualize	VERB
fnp-3679	191	11	by	by	ADP
fnp-3679	191	12	green	green	ADJ
fnp-3679	191	13	fluorescence	fluorescence	NOUN
fnp-3679	191	14	of	of	ADP
fnp-3679	191	15	atp5b	atp5b	PROPN
fnp-3679	191	16	,	,	PUNCT
fnp-3679	191	17	and	and	CCONJ
fnp-3679	191	18	one	one	NUM
fnp-3679	191	19	cluster	cluster	NOUN
fnp-3679	191	20	is	be	AUX
fnp-3679	191	21	surrounded	surround	VERB
fnp-3679	191	22	by	by	ADP
fnp-3679	191	23	a	a	DET
fnp-3679	191	24	rim	rim	NOUN
fnp-3679	191	25	of	of	ADP
fnp-3679	191	26	desmin	desmin	NOUN
fnp-3679	191	27	.	.	PUNCT
fnp-3679	192	1	in	in	ADP
fnp-3679	192	2	normal	normal	ADJ
fnp-3679	192	3	cardiomyocytes	cardiomyocyte	NOUN
fnp-3679	192	4	,	,	PUNCT
fnp-3679	192	5	mitochondria	mitochondria	PROPN
fnp-3679	192	6	occur	occur	VERB
fnp-3679	192	7	in	in	ADP
fnp-3679	192	8	rows	row	NOUN
fnp-3679	192	9	of	of	ADP
fnp-3679	192	10	delicate	delicate	ADJ
fnp-3679	192	11	granules	granule	NOUN
fnp-3679	192	12	between	between	ADP
fnp-3679	192	13	heart	heart	NOUN
fnp-3679	192	14	fibrils	fibril	NOUN
fnp-3679	192	15	(	(	PUNCT
fnp-3679	192	16	fig	fig	NOUN
fnp-3679	192	17	.	.	PUNCT
fnp-3679	193	1	8	8	NUM
fnp-3679	193	2	,	,	PUNCT
fnp-3679	193	3	top	top	ADJ
fnp-3679	193	4	row	row	NOUN
fnp-3679	193	5	)	)	PUNCT
fnp-3679	193	6	.	.	PUNCT
fnp-3679	194	1	figure	figure	VERB
fnp-3679	194	2	6	6	NUM
fnp-3679	194	3	.	.	PUNCT
fnp-3679	194	4	double	double	ADJ
fnp-3679	194	5	-	-	PUNCT
fnp-3679	194	6	label	label	NOUN
fnp-3679	194	7	laser	laser	NOUN
fnp-3679	194	8	scanning	scan	VERB
fnp-3679	194	9	confocal	confocal	ADJ
fnp-3679	194	10	immunofluorescence	immunofluorescence	NOUN
fnp-3679	194	11	microscopy	microscopy	NOUN
fnp-3679	194	12	of	of	ADP
fnp-3679	194	13	desmin	desmin	PROPN
fnp-3679	194	14	and	and	CCONJ
fnp-3679	194	15	αb	αb	NOUN
fnp-3679	194	16	-	-	PUNCT
fnp-3679	194	17	crystallin	crystallin	NOUN
fnp-3679	194	18	.	.	PUNCT
fnp-3679	195	1	desmin	desmin	ADJ
fnp-3679	195	2	immunofluorescence	immunofluorescence	NOUN
fnp-3679	195	3	(	(	PUNCT
fnp-3679	195	4	a	a	DET
fnp-3679	195	5	,	,	PUNCT
fnp-3679	195	6	d	d	NOUN
fnp-3679	195	7	)	)	PUNCT
fnp-3679	195	8	is	be	AUX
fnp-3679	195	9	alexa	alexa	ADJ
fnp-3679	195	10	fluor	fluor	NOUN
fnp-3679	195	11	488	488	NUM
fnp-3679	195	12	green	green	ADJ
fnp-3679	195	13	,	,	PUNCT
fnp-3679	195	14	αb	αb	NOUN
fnp-3679	195	15	-	-	NOUN
fnp-3679	195	16	crystallin	crystallin	NOUN
fnp-3679	195	17	(	(	PUNCT
fnp-3679	195	18	b	b	NOUN
fnp-3679	195	19	,	,	PUNCT
fnp-3679	195	20	e	e	NOUN
fnp-3679	195	21	)	)	PUNCT
fnp-3679	195	22	cy3	cy3	PROPN
fnp-3679	196	1	red	red	PROPN
fnp-3679	196	2	.	.	PUNCT
fnp-3679	197	1	merged	merge	VERB
fnp-3679	197	2	images	image	NOUN
fnp-3679	197	3	appear	appear	VERB
fnp-3679	197	4	in	in	ADP
fnp-3679	197	5	c	c	PROPN
fnp-3679	197	6	and	and	CCONJ
fnp-3679	197	7	f.	f.	PROPN
fnp-3679	197	8	the	the	DET
fnp-3679	197	9	top	top	ADJ
fnp-3679	197	10	panel	panel	NOUN
fnp-3679	197	11	(	(	PUNCT
fnp-3679	197	12	a	a	DET
fnp-3679	197	13	-	-	PUNCT
fnp-3679	197	14	c	c	NOUN
fnp-3679	197	15	)	)	PUNCT
fnp-3679	197	16	represents	represent	VERB
fnp-3679	197	17	a	a	DET
fnp-3679	197	18	normal	normal	ADJ
fnp-3679	197	19	control	control	NOUN
fnp-3679	197	20	,	,	PUNCT
fnp-3679	197	21	the	the	DET
fnp-3679	197	22	bottom	bottom	ADJ
fnp-3679	197	23	panel	panel	NOUN
fnp-3679	197	24	(	(	PUNCT
fnp-3679	197	25	d	d	X
fnp-3679	197	26	-	-	PUNCT
fnp-3679	197	27	f	f	NOUN
fnp-3679	197	28	)	)	PUNCT
fnp-3679	197	29	fa	fa	PROPN
fnp-3679	197	30	(	(	PUNCT
fnp-3679	197	31	man	man	NOUN
fnp-3679	197	32	,	,	PUNCT
fnp-3679	197	33	24	24	NUM
fnp-3679	197	34	,	,	PUNCT
fnp-3679	197	35	gaa	gaa	NOUN
fnp-3679	197	36	700/1050	700/1050	NUM
fnp-3679	197	37	)	)	PUNCT
fnp-3679	197	38	.	.	PUNCT
fnp-3679	198	1	desmin	desmin	ADJ
fnp-3679	198	2	and	and	CCONJ
fnp-3679	198	3	αb	αb	PROPN
fnp-3679	198	4	-	-	PUNCT
fnp-3679	198	5	crystallin	crystallin	NOUN
fnp-3679	198	6	fluorescence	fluorescence	NOUN
fnp-3679	198	7	colocalize	colocalize	NOUN
fnp-3679	198	8	at	at	ADP
fnp-3679	198	9	intercalated	intercalate	VERB
fnp-3679	198	10	discs	disc	NOUN
fnp-3679	198	11	(	(	PUNCT
fnp-3679	198	12	arrows	arrow	NOUN
fnp-3679	198	13	)	)	PUNCT
fnp-3679	198	14	and	and	CCONJ
fnp-3679	198	15	z	z	NOUN
fnp-3679	198	16	discs	disc	NOUN
fnp-3679	198	17	.	.	PUNCT
fnp-3679	199	1	in	in	ADP
fnp-3679	199	2	fa	fa	PROPN
fnp-3679	199	3	,	,	PUNCT
fnp-3679	199	4	an	an	DET
fnp-3679	199	5	intercalated	intercalated	ADJ
fnp-3679	199	6	disc	disc	NOUN
fnp-3679	199	7	has	have	AUX
fnp-3679	199	8	undergone	undergo	VERB
fnp-3679	199	9	chaotic	chaotic	ADJ
fnp-3679	199	10	modification	modification	NOUN
fnp-3679	199	11	.	.	PUNCT
fnp-3679	200	1	bars	bar	NOUN
fnp-3679	200	2	,	,	PUNCT
fnp-3679	200	3	10	10	NUM
fnp-3679	200	4	µm	µm	NOUN
fnp-3679	200	5	.	.	PUNCT
fnp-3679	200	6	figure	figure	NOUN
fnp-3679	200	7	7	7	NUM
fnp-3679	200	8	.	.	PUNCT
fnp-3679	201	1	desmin	desmin	ADJ
fnp-3679	201	2	and	and	CCONJ
fnp-3679	201	3	αb	αb	NOUN
fnp-3679	201	4	-	-	PUNCT
fnp-3679	201	5	crystallin	crystallin	NOUN
fnp-3679	201	6	overload	overload	NOUN
fnp-3679	201	7	in	in	ADP
fnp-3679	201	8	fa	fa	INTJ
fnp-3679	201	9	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	201	10	(	(	PUNCT
fnp-3679	201	11	same	same	ADJ
fnp-3679	201	12	patient	patient	NOUN
fnp-3679	201	13	as	as	ADP
fnp-3679	201	14	in	in	ADP
fnp-3679	201	15	fig	fig	NOUN
fnp-3679	201	16	.	.	PUNCT
fnp-3679	202	1	6	6	NUM
fnp-3679	202	2	)	)	PUNCT
fnp-3679	202	3	.	.	PUNCT
fnp-3679	203	1	desmin	desmin	PROPN
fnp-3679	203	2	is	be	AUX
fnp-3679	203	3	shown	show	VERB
fnp-3679	203	4	as	as	ADP
fnp-3679	203	5	alexa	alexa	NOUN
fnp-3679	203	6	fluor	fluor	NOUN
fnp-3679	203	7	488	488	NUM
fnp-3679	203	8	green	green	ADJ
fnp-3679	203	9	,	,	PUNCT
fnp-3679	203	10	αb	αb	NOUN
fnp-3679	203	11	-	-	NOUN
fnp-3679	203	12	crystallin	crystallin	NOUN
fnp-3679	203	13	as	as	ADP
fnp-3679	203	14	cy3	cy3	PROPN
fnp-3679	203	15	red	red	PROPN
fnp-3679	203	16	,	,	PUNCT
fnp-3679	203	17	the	the	DET
fnp-3679	203	18	merged	merged	ADJ
fnp-3679	203	19	image	image	NOUN
fnp-3679	203	20	on	on	ADP
fnp-3679	203	21	the	the	DET
fnp-3679	203	22	right	right	NOUN
fnp-3679	203	23	shows	show	VERB
fnp-3679	203	24	extensive	extensive	ADJ
fnp-3679	203	25	colocalization	colocalization	NOUN
fnp-3679	203	26	of	of	ADP
fnp-3679	203	27	these	these	DET
fnp-3679	203	28	protein	protein	NOUN
fnp-3679	203	29	and	and	CCONJ
fnp-3679	203	30	destructive	destructive	ADJ
fnp-3679	203	31	aggregation	aggregation	NOUN
fnp-3679	203	32	in	in	ADP
fnp-3679	203	33	two	two	NUM
fnp-3679	203	34	fibers	fiber	NOUN
fnp-3679	203	35	(	(	PUNCT
fnp-3679	203	36	arrows	arrow	NOUN
fnp-3679	203	37	)	)	PUNCT
fnp-3679	203	38	.	.	PUNCT
fnp-3679	204	1	bars	bar	NOUN
fnp-3679	204	2	,	,	PUNCT
fnp-3679	204	3	10	10	NUM
fnp-3679	204	4	μm	μm	NOUN
fnp-3679	204	5	.	.	PUNCT
fnp-3679	204	6	figure	figure	NOUN
fnp-3679	204	7	8	8	NUM
fnp-3679	204	8	.	.	PUNCT
fnp-3679	204	9	double	double	ADJ
fnp-3679	204	10	-	-	PUNCT
fnp-3679	204	11	label	label	NOUN
fnp-3679	204	12	laser	laser	NOUN
fnp-3679	204	13	scanning	scan	VERB
fnp-3679	204	14	confocal	confocal	ADJ
fnp-3679	204	15	immunofluorescence	immunofluorescence	NOUN
fnp-3679	204	16	microscopy	microscopy	NOUN
fnp-3679	204	17	of	of	ADP
fnp-3679	204	18	desmin	desmin	PROPN
fnp-3679	204	19	and	and	CCONJ
fnp-3679	204	20	atp5b	atp5b	PROPN
fnp-3679	204	21	.	.	PUNCT
fnp-3679	205	1	top	top	ADJ
fnp-3679	205	2	row	row	NOUN
fnp-3679	205	3	,	,	PUNCT
fnp-3679	205	4	normal	normal	ADJ
fnp-3679	205	5	control	control	NOUN
fnp-3679	205	6	;	;	PUNCT
fnp-3679	205	7	bottom	bottom	NOUN
fnp-3679	205	8	row	row	NOUN
fnp-3679	205	9	,	,	PUNCT
fnp-3679	205	10	fa	fa	PROPN
fnp-3679	205	11	(	(	PUNCT
fnp-3679	205	12	same	same	ADJ
fnp-3679	205	13	patient	patient	NOUN
fnp-3679	205	14	as	as	ADP
fnp-3679	205	15	in	in	ADP
fnp-3679	205	16	fig	fig	NOUN
fnp-3679	205	17	.	.	PUNCT
fnp-3679	206	1	5	5	NUM
fnp-3679	206	2	)	)	PUNCT
fnp-3679	206	3	.	.	PUNCT
fnp-3679	207	1	desmin	desmin	PROPN
fnp-3679	207	2	is	be	AUX
fnp-3679	207	3	shown	show	VERB
fnp-3679	207	4	as	as	ADP
fnp-3679	207	5	cy3	cy3	PROPN
fnp-3679	207	6	red	red	PROPN
fnp-3679	207	7	,	,	PUNCT
fnp-3679	207	8	atp5b	atp5b	VERB
fnp-3679	207	9	as	as	ADP
fnp-3679	207	10	alexa	alexa	PROPN
fnp-3679	207	11	fluor	fluor	NOUN
fnp-3679	207	12	488	488	NUM
fnp-3679	207	13	green	green	NOUN
fnp-3679	207	14	.	.	PUNCT
fnp-3679	208	1	in	in	ADP
fnp-3679	208	2	the	the	DET
fnp-3679	208	3	normal	normal	ADJ
fnp-3679	208	4	control	control	NOUN
fnp-3679	208	5	,	,	PUNCT
fnp-3679	208	6	mitochondria	mitochondria	PROPN
fnp-3679	208	7	appear	appear	VERB
fnp-3679	208	8	as	as	ADP
fnp-3679	208	9	rows	row	NOUN
fnp-3679	208	10	of	of	ADP
fnp-3679	208	11	punctate	punctate	ADJ
fnp-3679	208	12	green	green	ADJ
fnp-3679	208	13	organelles	organelle	NOUN
fnp-3679	208	14	aligned	align	VERB
fnp-3679	208	15	along	along	ADP
fnp-3679	208	16	fibrils	fibril	NOUN
fnp-3679	208	17	.	.	PUNCT
fnp-3679	209	1	in	in	ADP
fnp-3679	209	2	fa	fa	PROPN
fnp-3679	209	3	,	,	PUNCT
fnp-3679	209	4	green	green	ADJ
fnp-3679	209	5	mitochondria	mitochondria	PROPN
fnp-3679	209	6	appear	appear	VERB
fnp-3679	209	7	in	in	ADP
fnp-3679	209	8	clusters	cluster	NOUN
fnp-3679	209	9	(	(	PUNCT
fnp-3679	209	10	arrows	arrow	NOUN
fnp-3679	209	11	)	)	PUNCT
fnp-3679	209	12	.	.	PUNCT
fnp-3679	210	1	the	the	DET
fnp-3679	210	2	upper	upper	ADJ
fnp-3679	210	3	cluster	cluster	NOUN
fnp-3679	210	4	is	be	AUX
fnp-3679	210	5	surrounded	surround	VERB
fnp-3679	210	6	by	by	ADP
fnp-3679	210	7	a	a	DET
fnp-3679	210	8	desmin	desmin	ADJ
fnp-3679	210	9	deposit	deposit	NOUN
fnp-3679	210	10	.	.	PUNCT
fnp-3679	211	1	bars	bar	NOUN
fnp-3679	211	2	,	,	PUNCT
fnp-3679	211	3	20	20	NUM
fnp-3679	211	4	µm	µm	NOUN
fnp-3679	211	5	.	.	PUNCT
fnp-3679	212	1	discussion	discussion	NOUN
fnp-3679	212	2	frataxin	frataxin	NOUN
fnp-3679	212	3	levels	level	NOUN
fnp-3679	212	4	in	in	ADP
fnp-3679	212	5	fa	fa	PROPN
fnp-3679	212	6	hearts	heart	NOUN
fnp-3679	212	7	:	:	PUNCT
fnp-3679	212	8	the	the	DET
fnp-3679	212	9	detection	detection	NOUN
fnp-3679	212	10	limit	limit	NOUN
fnp-3679	212	11	of	of	ADP
fnp-3679	212	12	the	the	DET
fnp-3679	212	13	described	describe	VERB
fnp-3679	212	14	elisa	elisa	NOUN
fnp-3679	212	15	is	be	AUX
fnp-3679	212	16	10	10	NUM
fnp-3679	212	17	pg	pg	NOUN
fnp-3679	212	18	.	.	PUNCT
fnp-3679	213	1	we	we	PRON
fnp-3679	213	2	followed	follow	VERB
fnp-3679	213	3	biochemical	biochemical	ADJ
fnp-3679	213	4	tradition	tradition	NOUN
fnp-3679	213	5	by	by	ADP
fnp-3679	213	6	expressing	express	VERB
fnp-3679	213	7	frataxin	frataxin	NOUN
fnp-3679	213	8	levels	level	NOUN
fnp-3679	213	9	as	as	ADP
fnp-3679	213	10	mass	mass	NOUN
fnp-3679	213	11	per	per	ADP
fnp-3679	213	12	gram	gram	X
fnp-3679	213	13	wet	wet	ADJ
fnp-3679	213	14	weight	weight	NOUN
fnp-3679	213	15	,	,	PUNCT
fnp-3679	213	16	which	which	PRON
fnp-3679	213	17	is	be	AUX
fnp-3679	213	18	at	at	ADP
fnp-3679	213	19	variance	variance	NOUN
fnp-3679	213	20	with	with	ADP
fnp-3679	213	21	the	the	DET
fnp-3679	213	22	current	current	ADJ
fnp-3679	213	23	practice	practice	NOUN
fnp-3679	213	24	of	of	ADP
fnp-3679	213	25	fa	fa	PROPN
fnp-3679	213	26	investigators	investigator	NOUN
fnp-3679	213	27	to	to	PART
fnp-3679	213	28	express	express	VERB
fnp-3679	213	29	frataxin	frataxin	NOUN
fnp-3679	213	30	as	as	ADP
fnp-3679	213	31	ng	ng	PROPN
fnp-3679	213	32	/	/	SYM
fnp-3679	213	33	total	total	ADJ
fnp-3679	213	34	protein	protein	NOUN
fnp-3679	213	35	.	.	PUNCT
fnp-3679	214	1	the	the	DET
fnp-3679	214	2	data	datum	NOUN
fnp-3679	214	3	must	must	AUX
fnp-3679	214	4	be	be	AUX
fnp-3679	214	5	interpreted	interpret	VERB
fnp-3679	214	6	with	with	ADP
fnp-3679	214	7	some	some	DET
fnp-3679	214	8	caution	caution	NOUN
fnp-3679	214	9	because	because	SCONJ
fnp-3679	214	10	we	we	PRON
fnp-3679	214	11	assumed	assume	VERB
fnp-3679	214	12	that	that	SCONJ
fnp-3679	214	13	the	the	DET
fnp-3679	214	14	wet	wet	ADJ
fnp-3679	214	15	weight	weight	NOUN
fnp-3679	214	16	of	of	ADP
fnp-3679	214	17	normal	normal	ADJ
fnp-3679	214	18	and	and	CCONJ
fnp-3679	214	19	fa	fa	NOUN
fnp-3679	214	20	heart	heart	NOUN
fnp-3679	214	21	tissues	tissue	NOUN
fnp-3679	214	22	was	be	AUX
fnp-3679	214	23	close	close	ADJ
fnp-3679	214	24	to	to	ADP
fnp-3679	214	25	its	its	PRON
fnp-3679	214	26	water	water	NOUN
fnp-3679	214	27	content	content	NOUN
fnp-3679	214	28	.	.	PUNCT
fnp-3679	215	1	tissue	tissue	NOUN
fnp-3679	215	2	lysates	lysate	NOUN
fnp-3679	215	3	contained	contain	VERB
fnp-3679	215	4	inhibitory	inhibitory	ADJ
fnp-3679	215	5	substances	substance	NOUN
fnp-3679	215	6	that	that	PRON
fnp-3679	215	7	interfered	interfere	VERB
fnp-3679	215	8	with	with	ADP
fnp-3679	215	9	elisa	elisa	PROPN
fnp-3679	215	10	.	.	PUNCT
fnp-3679	215	11	filtration	filtration	NOUN
fnp-3679	215	12	through	through	ADP
fnp-3679	215	13	membranes	membrane	NOUN
fnp-3679	215	14	with	with	ADP
fnp-3679	215	15	a	a	DET
fnp-3679	215	16	molecular	molecular	ADJ
fnp-3679	215	17	mass	mass	NOUN
fnp-3679	215	18	cutoff	cutoff	NOUN
fnp-3679	215	19	of	of	ADP
fnp-3679	215	20	30	30	NUM
fnp-3679	215	21	kda	kda	NOUN
fnp-3679	215	22	removed	remove	VERB
fnp-3679	215	23	the	the	DET
fnp-3679	215	24	interference	interference	NOUN
fnp-3679	215	25	but	but	CCONJ
fnp-3679	215	26	may	may	AUX
fnp-3679	215	27	have	have	AUX
fnp-3679	215	28	introduced	introduce	VERB
fnp-3679	215	29	an	an	DET
fnp-3679	215	30	additional	additional	ADJ
fnp-3679	215	31	error	error	NOUN
fnp-3679	215	32	in	in	ADP
fnp-3679	215	33	the	the	DET
fnp-3679	215	34	calculation	calculation	NOUN
fnp-3679	215	35	of	of	ADP
fnp-3679	215	36	corresponding	correspond	VERB
fnp-3679	215	37	wet	wet	ADJ
fnp-3679	215	38	weight	weight	NOUN
fnp-3679	215	39	.	.	PUNCT
fnp-3679	216	1	desmin	desmin	ADJ
fnp-3679	216	2	in	in	ADP
fnp-3679	216	3	fa	fa	PROPN
fnp-3679	216	4	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	216	5	:	:	PUNCT
fnp-3679	216	6	uniprot	uniprot	ADJ
fnp-3679	216	7	(	(	PUNCT
fnp-3679	216	8	2021	2021	NUM
fnp-3679	216	9	)	)	PUNCT
fnp-3679	216	10	identifies	identify	VERB
fnp-3679	216	11	36	36	NUM
fnp-3679	216	12	natural	natural	ADJ
fnp-3679	216	13	variants	variant	NOUN
fnp-3679	216	14	of	of	ADP
fnp-3679	216	15	human	human	ADJ
fnp-3679	216	16	desmin	desmin	NOUN
fnp-3679	216	17	,	,	PUNCT
fnp-3679	216	18	of	of	ADP
fnp-3679	216	19	which	which	PRON
fnp-3679	216	20	some	some	PRON
fnp-3679	216	21	are	be	AUX
fnp-3679	216	22	pathogenic	pathogenic	ADJ
fnp-3679	216	23	mutations	mutation	NOUN
fnp-3679	216	24	.	.	PUNCT
fnp-3679	217	1	none	none	NOUN
fnp-3679	217	2	are	be	AUX
fnp-3679	217	3	listed	list	VERB
fnp-3679	217	4	that	that	PRON
fnp-3679	217	5	could	could	AUX
fnp-3679	217	6	account	account	VERB
fnp-3679	217	7	for	for	ADP
fnp-3679	217	8	the	the	DET
fnp-3679	217	9	deletion	deletion	NOUN
fnp-3679	217	10	of	of	ADP
fnp-3679	217	11	an	an	DET
fnp-3679	217	12	estimated	estimate	VERB
fnp-3679	217	13	80	80	NUM
fnp-3679	217	14	amino	amino	NOUN
fnp-3679	217	15	acids	acid	NOUN
fnp-3679	217	16	that	that	PRON
fnp-3679	217	17	would	would	AUX
fnp-3679	217	18	explain	explain	VERB
fnp-3679	217	19	the	the	DET
fnp-3679	217	20	high	high	ADJ
fnp-3679	217	21	signal	signal	NOUN
fnp-3679	217	22	desmin	desmin	NOUN
fnp-3679	217	23	isoprotein	isoprotein	ADP
fnp-3679	217	24	of	of	ADP
fnp-3679	217	25	45	45	NUM
fnp-3679	217	26	kda	kda	NOUN
fnp-3679	217	27	in	in	ADP
fnp-3679	217	28	fa	fa	PROPN
fnp-3679	217	29	hearts	heart	NOUN
fnp-3679	217	30	(	(	PUNCT
fnp-3679	217	31	figs	fig	NOUN
fnp-3679	217	32	.	.	X
fnp-3679	217	33	2	2	NUM
fnp-3679	217	34	and	and	CCONJ
fnp-3679	217	35	3	3	NUM
fnp-3679	217	36	)	)	PUNCT
fnp-3679	217	37	.	.	PUNCT
fnp-3679	218	1	clemen	clemen	PROPN
fnp-3679	218	2	et	et	PROPN
fnp-3679	218	3	al	al	PROPN
fnp-3679	218	4	.	.	PROPN
fnp-3679	219	1	(	(	PUNCT
fnp-3679	219	2	2008	2008	NUM
fnp-3679	219	3	)	)	PUNCT
fnp-3679	219	4	attributed	attribute	VERB
fnp-3679	219	5	pathogenicity	pathogenicity	NOUN
fnp-3679	219	6	in	in	ADP
fnp-3679	219	7	patients	patient	NOUN
fnp-3679	219	8	with	with	ADP
fnp-3679	219	9	skeletal	skeletal	ADJ
fnp-3679	219	10	muscle	muscle	NOUN
fnp-3679	219	11	desminopathy	desminopathy	ADJ
fnp-3679	219	12	to	to	ADP
fnp-3679	219	13	the	the	DET
fnp-3679	219	14	presence	presence	NOUN
fnp-3679	219	15	of	of	ADP
fnp-3679	219	16	a	a	DET
fnp-3679	219	17	low	low	ADJ
fnp-3679	219	18	-	-	PUNCT
fnp-3679	219	19	abundance	abundance	NOUN
fnp-3679	219	20	truncated	truncate	VERB
fnp-3679	219	21	desmin	desmin	NOUN
fnp-3679	219	22	.	.	PUNCT
fnp-3679	220	1	it	it	PRON
fnp-3679	220	2	is	be	AUX
fnp-3679	220	3	unknown	unknown	ADJ
fnp-3679	220	4	whether	whether	SCONJ
fnp-3679	220	5	this	this	DET
fnp-3679	220	6	pathological	pathological	ADJ
fnp-3679	220	7	mechanism	mechanism	NOUN
fnp-3679	220	8	is	be	AUX
fnp-3679	220	9	analogous	analogous	ADJ
fnp-3679	220	10	to	to	ADP
fnp-3679	220	11	the	the	DET
fnp-3679	220	12	prominent	prominent	ADJ
fnp-3679	220	13	desmin	desmin	ADJ
fnp-3679	220	14	band	band	NOUN
fnp-3679	220	15	on	on	ADP
fnp-3679	220	16	our	our	PRON
fnp-3679	220	17	western	western	ADJ
fnp-3679	220	18	blots	blot	NOUN
fnp-3679	220	19	of	of	ADP
fnp-3679	220	20	fa	fa	NOUN
fnp-3679	220	21	patients	patient	NOUN
fnp-3679	220	22	(	(	PUNCT
fnp-3679	220	23	fig.3	fig.3	PROPN
fnp-3679	220	24	)	)	PUNCT
fnp-3679	220	25	.	.	PUNCT
fnp-3679	221	1	desmin	desmin	PROPN
fnp-3679	221	2	is	be	AUX
fnp-3679	221	3	not	not	PART
fnp-3679	221	4	mutated	mutate	VERB
fnp-3679	221	5	in	in	ADP
fnp-3679	221	6	fa	fa	PROPN
fnp-3679	221	7	,	,	PUNCT
fnp-3679	221	8	and	and	CCONJ
fnp-3679	221	9	fa	fa	PROPN
fnp-3679	221	10	patients	patient	NOUN
fnp-3679	221	11	have	have	VERB
fnp-3679	221	12	no	no	DET
fnp-3679	221	13	skeletal	skeletal	ADJ
fnp-3679	221	14	myopathy	myopathy	ADJ
fnp-3679	221	15	.	.	PUNCT
fnp-3679	222	1	arbustini	arbustini	PROPN
fnp-3679	222	2	et	et	PROPN
fnp-3679	222	3	al	al	PROPN
fnp-3679	222	4	.	.	PUNCT
fnp-3679	223	1	(	(	PUNCT
fnp-3679	223	2	1998	1998	NUM
fnp-3679	223	3	)	)	PUNCT
fnp-3679	223	4	presented	present	VERB
fnp-3679	223	5	western	western	ADJ
fnp-3679	223	6	blots	blot	NOUN
fnp-3679	223	7	of	of	ADP
fnp-3679	223	8	heart	heart	NOUN
fnp-3679	223	9	and	and	CCONJ
fnp-3679	223	10	muscle	muscle	NOUN
fnp-3679	223	11	lysates	lysate	NOUN
fnp-3679	223	12	from	from	ADP
fnp-3679	223	13	patients	patient	NOUN
fnp-3679	223	14	with	with	ADP
fnp-3679	223	15	desmin	desmin	ADV
fnp-3679	223	16	-	-	PUNCT
fnp-3679	223	17	related	relate	VERB
fnp-3679	223	18	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	223	19	that	that	PRON
fnp-3679	223	20	showed	show	VERB
fnp-3679	223	21	two	two	NUM
fnp-3679	223	22	isoforms	isoform	NOUN
fnp-3679	223	23	of	of	ADP
fnp-3679	223	24	desmin	desmin	NOUN
fnp-3679	223	25	of	of	ADP
fnp-3679	223	26	about	about	ADV
fnp-3679	223	27	the	the	DET
fnp-3679	223	28	same	same	ADJ
fnp-3679	223	29	intensity	intensity	NOUN
fnp-3679	223	30	at	at	ADP
fnp-3679	223	31	masses	masse	NOUN
fnp-3679	223	32	of	of	ADP
fnp-3679	223	33	55	55	NUM
fnp-3679	223	34	and	and	CCONJ
fnp-3679	223	35	53	53	NUM
fnp-3679	223	36	kda	kda	NOUN
fnp-3679	223	37	,	,	PUNCT
fnp-3679	223	38	respectively	respectively	ADV
fnp-3679	223	39	.	.	PUNCT
fnp-3679	224	1	a	a	DET
fnp-3679	224	2	truncated	truncated	ADJ
fnp-3679	224	3	muscle	muscle	NOUN
fnp-3679	224	4	desmin	desmin	NOUN
fnp-3679	224	5	of	of	ADP
fnp-3679	224	6	the	the	DET
fnp-3679	224	7	cases	case	NOUN
fnp-3679	224	8	of	of	ADP
fnp-3679	224	9	skeletal	skeletal	ADJ
fnp-3679	224	10	myopathy	myopathy	NOUN
fnp-3679	224	11	reported	report	VERB
fnp-3679	224	12	by	by	ADP
fnp-3679	224	13	clemen	cleman	NOUN
fnp-3679	224	14	et	et	PROPN
fnp-3679	224	15	al	al	PROPN
fnp-3679	224	16	.	.	PROPN
fnp-3679	224	17	(	(	PUNCT
fnp-3679	224	18	2008	2008	NUM
fnp-3679	224	19	)	)	PUNCT
fnp-3679	224	20	migrated	migrate	VERB
fnp-3679	224	21	at	at	ADP
fnp-3679	224	22	54	54	NUM
fnp-3679	224	23	kda	kda	NOUN
fnp-3679	224	24	,	,	PUNCT
fnp-3679	224	25	rather	rather	ADV
fnp-3679	224	26	than	than	ADP
fnp-3679	224	27	the	the	DET
fnp-3679	224	28	45	45	NUM
fnp-3679	224	29	kda	kda	NOUN
fnp-3679	224	30	in	in	ADP
fnp-3679	224	31	the	the	DET
fnp-3679	224	32	lysates	lysate	NOUN
fnp-3679	224	33	of	of	ADP
fnp-3679	224	34	fa	fa	PROPN
fnp-3679	224	35	hearts	heart	NOUN
fnp-3679	224	36	reported	report	VERB
fnp-3679	224	37	here	here	ADV
fnp-3679	224	38	(	(	PUNCT
fnp-3679	224	39	figs	fig	NOUN
fnp-3679	224	40	.	.	X
fnp-3679	224	41	2	2	NUM
fnp-3679	224	42	and	and	CCONJ
fnp-3679	224	43	3	3	NUM
fnp-3679	224	44	)	)	PUNCT
fnp-3679	224	45	.	.	PUNCT
fnp-3679	225	1	we	we	PRON
fnp-3679	225	2	assume	assume	VERB
fnp-3679	225	3	that	that	SCONJ
fnp-3679	225	4	the	the	DET
fnp-3679	225	5	truncated	truncated	ADJ
fnp-3679	225	6	desmin	desmin	NOUN
fnp-3679	225	7	in	in	ADP
fnp-3679	225	8	fa	fa	PROPN
fnp-3679	225	9	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	225	10	derives	derive	VERB
fnp-3679	225	11	from	from	ADP
fnp-3679	225	12	normal	normal	ADJ
fnp-3679	225	13	desmin	desmin	NOUN
fnp-3679	225	14	by	by	ADP
fnp-3679	225	15	proteolysis	proteolysis	NOUN
fnp-3679	225	16	(	(	PUNCT
fnp-3679	225	17	fig	fig	NOUN
fnp-3679	225	18	.	.	PUNCT
fnp-3679	226	1	2	2	NUM
fnp-3679	226	2	)	)	PUNCT
fnp-3679	226	3	.	.	PUNCT
fnp-3679	227	1	the	the	DET
fnp-3679	227	2	functional	functional	ADJ
fnp-3679	227	3	role	role	NOUN
fnp-3679	227	4	of	of	ADP
fnp-3679	227	5	desmin	desmin	ADV
fnp-3679	227	6	-	-	PUNCT
fnp-3679	227	7	containing	contain	VERB
fnp-3679	227	8	intermediate	intermediate	ADJ
fnp-3679	227	9	filaments	filament	NOUN
fnp-3679	227	10	in	in	ADP
fnp-3679	227	11	skeletal	skeletal	ADJ
fnp-3679	227	12	and	and	CCONJ
fnp-3679	227	13	cardiac	cardiac	ADJ
fnp-3679	227	14	muscle	muscle	NOUN
fnp-3679	227	15	is	be	AUX
fnp-3679	227	16	complex	complex	ADJ
fnp-3679	227	17	.	.	PUNCT
fnp-3679	228	1	authors	author	NOUN
fnp-3679	228	2	who	who	PRON
fnp-3679	228	3	published	publish	VERB
fnp-3679	228	4	three	three	NUM
fnp-3679	228	5	-	-	PUNCT
fnp-3679	228	6	dimensional	dimensional	ADJ
fnp-3679	228	7	renditions	rendition	NOUN
fnp-3679	228	8	of	of	ADP
fnp-3679	228	9	desmin	desmin	NOUN
fnp-3679	228	10	in	in	ADP
fnp-3679	228	11	skeletal	skeletal	ADJ
fnp-3679	228	12	muscle	muscle	NOUN
fnp-3679	228	13	(	(	PUNCT
fnp-3679	228	14	goldfarb	goldfarb	PROPN
fnp-3679	228	15	and	and	CCONJ
fnp-3679	228	16	dalakas	dalakas	PROPN
fnp-3679	228	17	,	,	PUNCT
fnp-3679	228	18	2009	2009	NUM
fnp-3679	228	19	;	;	PUNCT
fnp-3679	228	20	clemen	cleman	NOUN
fnp-3679	228	21	et	et	PROPN
fnp-3679	228	22	al	al	PROPN
fnp-3679	228	23	.	.	PROPN
fnp-3679	228	24	,	,	PUNCT
fnp-3679	228	25	2013	2013	NUM
fnp-3679	228	26	)	)	PUNCT
fnp-3679	228	27	and	and	CCONJ
fnp-3679	228	28	heart	heart	NOUN
fnp-3679	228	29	muscle	muscle	NOUN
fnp-3679	228	30	(	(	PUNCT
fnp-3679	228	31	capetanaki	capetanaki	NOUN
fnp-3679	228	32	et	et	PROPN
fnp-3679	228	33	al	al	PROPN
fnp-3679	228	34	.	.	PROPN
fnp-3679	228	35	,	,	PUNCT
fnp-3679	228	36	2015	2015	NUM
fnp-3679	228	37	)	)	PUNCT
fnp-3679	228	38	emphasized	emphasize	VERB
fnp-3679	228	39	the	the	DET
fnp-3679	228	40	localization	localization	NOUN
fnp-3679	228	41	of	of	ADP
fnp-3679	228	42	the	the	DET
fnp-3679	228	43	protein	protein	NOUN
fnp-3679	228	44	at	at	ADP
fnp-3679	228	45	z	z	NOUN
fnp-3679	228	46	discs	disc	NOUN
fnp-3679	228	47	and	and	CCONJ
fnp-3679	228	48	intercalated	intercalated	ADJ
fnp-3679	228	49	discs	disc	NOUN
fnp-3679	228	50	(	(	PUNCT
fnp-3679	228	51	heart	heart	NOUN
fnp-3679	228	52	only	only	ADV
fnp-3679	228	53	)	)	PUNCT
fnp-3679	228	54	,	,	PUNCT
fnp-3679	228	55	but	but	CCONJ
fnp-3679	228	56	also	also	ADV
fnp-3679	228	57	near	near	ADP
fnp-3679	228	58	the	the	DET
fnp-3679	228	59	nuclear	nuclear	ADJ
fnp-3679	228	60	and	and	CCONJ
fnp-3679	228	61	sarcoplasmic	sarcoplasmic	ADJ
fnp-3679	228	62	membranes	membrane	NOUN
fnp-3679	228	63	,	,	PUNCT
fnp-3679	228	64	and	and	CCONJ
fnp-3679	228	65	surrounding	surround	VERB
fnp-3679	228	66	mitochondria	mitochondria	NOUN
fnp-3679	228	67	.	.	PUNCT
fnp-3679	229	1	the	the	DET
fnp-3679	229	2	role	role	NOUN
fnp-3679	229	3	of	of	ADP
fnp-3679	229	4	αb	αb	PROPN
fnp-3679	229	5	-	-	NOUN
fnp-3679	229	6	crystallin	crystallin	NOUN
fnp-3679	229	7	in	in	ADP
fnp-3679	229	8	possible	possible	ADJ
fnp-3679	229	9	proteolysis	proteolysis	NOUN
fnp-3679	229	10	and	and	CCONJ
fnp-3679	229	11	aggregation	aggregation	NOUN
fnp-3679	229	12	of	of	ADP
fnp-3679	229	13	desmin	desmin	NOUN
fnp-3679	229	14	in	in	ADP
fnp-3679	229	15	fa	fa	PROPN
fnp-3679	229	16	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	229	17	is	be	AUX
fnp-3679	229	18	uncertain	uncertain	ADJ
fnp-3679	229	19	,	,	PUNCT
fnp-3679	229	20	but	but	CCONJ
fnp-3679	229	21	αb	αb	NOUN
fnp-3679	229	22	-	-	PUNCT
fnp-3679	229	23	crystallin	crystallin	PROPN
fnp-3679	229	24	is	be	AUX
fnp-3679	229	25	viewed	view	VERB
fnp-3679	229	26	as	as	ADP
fnp-3679	229	27	essential	essential	ADJ
fnp-3679	229	28	for	for	ADP
fnp-3679	229	29	the	the	DET
fnp-3679	229	30	proper	proper	ADJ
fnp-3679	229	31	assembly	assembly	NOUN
fnp-3679	229	32	of	of	ADP
fnp-3679	229	33	mature	mature	ADJ
fnp-3679	229	34	desmin	desmin	ADJ
fnp-3679	229	35	filaments	filament	NOUN
fnp-3679	229	36	(	(	PUNCT
fnp-3679	229	37	ghosh	ghosh	PROPN
fnp-3679	229	38	et	et	PROPN
fnp-3679	229	39	al	al	PROPN
fnp-3679	229	40	.	.	PROPN
fnp-3679	229	41	,	,	PUNCT
fnp-3679	229	42	2007	2007	NUM
fnp-3679	229	43	;	;	PUNCT
fnp-3679	229	44	sharma	sharma	PROPN
fnp-3679	229	45	et	et	PROPN
fnp-3679	229	46	al	al	PROPN
fnp-3679	229	47	.	.	PROPN
fnp-3679	229	48	,	,	PUNCT
fnp-3679	229	49	2017	2017	NUM
fnp-3679	229	50	)	)	PUNCT
fnp-3679	229	51	.	.	PUNCT
fnp-3679	230	1	peculiarly	peculiarly	ADV
fnp-3679	230	2	,	,	PUNCT
fnp-3679	230	3	mutations	mutation	NOUN
fnp-3679	230	4	of	of	ADP
fnp-3679	230	5	αb	αb	PROPN
fnp-3679	230	6	-	-	PUNCT
fnp-3679	230	7	crystallin	crystallin	NOUN
fnp-3679	230	8	cause	cause	VERB
fnp-3679	230	9	myopathy	myopathy	ADJ
fnp-3679	230	10	with	with	ADP
fnp-3679	230	11	a	a	DET
fnp-3679	230	12	phenotype	phenotype	NOUN
fnp-3679	230	13	that	that	PRON
fnp-3679	230	14	is	be	AUX
fnp-3679	230	15	very	very	ADV
fnp-3679	230	16	similar	similar	ADJ
fnp-3679	230	17	to	to	ADP
fnp-3679	230	18	desmin	desmin	ADJ
fnp-3679	230	19	myopathy	myopathy	ADJ
fnp-3679	230	20	,	,	PUNCT
fnp-3679	230	21	including	include	VERB
fnp-3679	230	22	desmin	desmin	ADJ
fnp-3679	230	23	accumulation	accumulation	NOUN
fnp-3679	230	24	in	in	ADP
fnp-3679	230	25	muscle	muscle	NOUN
fnp-3679	230	26	tissue	tissue	NOUN
fnp-3679	230	27	(	(	PUNCT
fnp-3679	230	28	goldfarb	goldfarb	PROPN
fnp-3679	230	29	et	et	PROPN
fnp-3679	230	30	al	al	PROPN
fnp-3679	230	31	.	.	PROPN
fnp-3679	230	32	,	,	PUNCT
fnp-3679	230	33	2004	2004	NUM
fnp-3679	230	34	)	)	PUNCT
fnp-3679	230	35	.	.	PUNCT
fnp-3679	231	1	autosomal	autosomal	ADJ
fnp-3679	231	2	dominant	dominant	ADJ
fnp-3679	231	3	mutations	mutation	NOUN
fnp-3679	231	4	in	in	ADP
fnp-3679	231	5	the	the	DET
fnp-3679	231	6	desmin	desmin	ADJ
fnp-3679	231	7	gene	gene	NOUN
fnp-3679	231	8	cause	cause	VERB
fnp-3679	231	9	desmin	desmin	ADJ
fnp-3679	231	10	myopathy	myopathy	NOUN
fnp-3679	231	11	that	that	PRON
fnp-3679	231	12	may	may	AUX
fnp-3679	231	13	be	be	AUX
fnp-3679	231	14	followed	follow	VERB
fnp-3679	231	15	by	by	ADP
fnp-3679	231	16	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	231	17	later	later	ADV
fnp-3679	231	18	in	in	ADP
fnp-3679	231	19	the	the	DET
fnp-3679	231	20	course	course	NOUN
fnp-3679	231	21	of	of	ADP
fnp-3679	231	22	the	the	DET
fnp-3679	231	23	disease	disease	NOUN
fnp-3679	231	24	.	.	PUNCT
fnp-3679	232	1	in	in	ADP
fnp-3679	232	2	contrast	contrast	NOUN
fnp-3679	232	3	,	,	PUNCT
fnp-3679	232	4	the	the	DET
fnp-3679	232	5	desmin	desmin	ADJ
fnp-3679	232	6	cardiomyopathy	cardiomyopathy	NOUN
fnp-3679	232	7	reported	report	VERB
fnp-3679	232	8	here	here	ADV
fnp-3679	232	9	is	be	AUX
fnp-3679	232	10	not	not	PART
fnp-3679	232	11	followed	follow	VERB
fnp-3679	232	12	by	by	ADP
fnp-3679	232	13	skeletal	skeletal	ADJ
fnp-3679	232	14	myopathy	myopathy	ADJ
fnp-3679	232	15	.	.	PUNCT
fnp-3679	233	1	desmin	desmin	ADJ
fnp-3679	233	2	and	and	CCONJ
fnp-3679	233	3	mitochondria	mitochondria	VERB
fnp-3679	233	4	in	in	ADP
fnp-3679	233	5	fa	fa	PROPN
fnp-3679	233	6	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	233	7	:	:	PUNCT
fnp-3679	233	8	frataxin	frataxin	NOUN
fnp-3679	233	9	is	be	AUX
fnp-3679	233	10	a	a	DET
fnp-3679	233	11	mitochondrial	mitochondrial	ADJ
fnp-3679	233	12	protein	protein	NOUN
fnp-3679	233	13	,	,	PUNCT
fnp-3679	233	14	and	and	CCONJ
fnp-3679	233	15	fa	fa	PROPN
fnp-3679	233	16	is	be	AUX
fnp-3679	233	17	a	a	DET
fnp-3679	233	18	mitochondrial	mitochondrial	ADJ
fnp-3679	233	19	disease	disease	NOUN
fnp-3679	233	20	.	.	PUNCT
fnp-3679	234	1	figure	figure	NOUN
fnp-3679	234	2	8	8	NUM
fnp-3679	234	3	illustrates	illustrate	VERB
fnp-3679	234	4	the	the	DET
fnp-3679	234	5	clustering	clustering	NOUN
fnp-3679	234	6	of	of	ADP
fnp-3679	234	7	mitochondria	mitochondria	NOUN
fnp-3679	234	8	near	near	ADP
fnp-3679	234	9	desmin	desmin	ADJ
fnp-3679	234	10	aggregates	aggregate	NOUN
fnp-3679	234	11	,	,	PUNCT
fnp-3679	234	12	but	but	CCONJ
fnp-3679	234	13	it	it	PRON
fnp-3679	234	14	is	be	AUX
fnp-3679	234	15	unknown	unknown	ADJ
fnp-3679	234	16	whether	whether	SCONJ
fnp-3679	234	17	this	this	DET
fnp-3679	234	18	seeming	seem	VERB
fnp-3679	234	19	entrapment	entrapment	NOUN
fnp-3679	234	20	impairs	impair	VERB
fnp-3679	234	21	mitochondrial	mitochondrial	ADJ
fnp-3679	234	22	function	function	NOUN
fnp-3679	234	23	in	in	ADP
fnp-3679	234	24	fa	fa	PROPN
fnp-3679	234	25	.	.	PUNCT
fnp-3679	234	26	references	reference	NOUN
fnp-3679	234	27	agnetti	agnetti	VERB
fnp-3679	234	28	g	g	PROPN
fnp-3679	234	29	,	,	PUNCT
fnp-3679	234	30	halperin	halperin	PROPN
fnp-3679	234	31	vl	vl	PROPN
fnp-3679	234	32	,	,	PUNCT
fnp-3679	234	33	kirek	kirek	PROPN
fnp-3679	234	34	ja	ja	PROPN
fnp-3679	234	35	,	,	PUNCT
fnp-3679	234	36	chakire	chakire	NOUN
fnp-3679	234	37	k	k	PROPN
fnp-3679	234	38	,	,	PUNCT
fnp-3679	234	39	guo	guo	PROPN
fnp-3679	234	40	yj	yj	PROPN
fnp-3679	234	41	,	,	PUNCT
fnp-3679	234	42	lund	lund	PROPN
fnp-3679	234	43	l	l	PROPN
fnp-3679	234	44	,	,	PUNCT
fnp-3679	234	45	nicolini	nicolini	PROPN
fnp-3679	234	46	f	f	PROPN
fnp-3679	234	47	,	,	PUNCT
fnp-3679	234	48	gherli	gherli	PROPN
fnp-3679	234	49	t	t	PROPN
fnp-3679	234	50	,	,	PUNCT
fnp-3679	234	51	guarnieri	guarnieri	PROPN
fnp-3679	234	52	c	c	PROPN
fnp-3679	234	53	,	,	PUNCT
fnp-3679	234	54	caldarera	caldarera	NOUN
fnp-3679	234	55	cm	cm	PROPN
fnp-3679	234	56	,	,	PUNCT
fnp-3679	234	57	tomaselli	tomaselli	PROPN
fnp-3679	234	58	gf	gf	PROPN
fnp-3679	234	59	,	,	PUNCT
fnp-3679	234	60	kass	kass	PROPN
fnp-3679	234	61	da	da	PROPN
fnp-3679	234	62	,	,	PUNCT
fnp-3679	235	1	van	van	PROPN
fnp-3679	235	2	eyk	eyk	PROPN
fnp-3679	235	3	je	je	PROPN
fnp-3679	235	4	.	.	PUNCT
fnp-3679	236	1	desmin	desmin	ADJ
fnp-3679	236	2	modifications	modification	NOUN
fnp-3679	236	3	associate	associate	VERB
fnp-3679	236	4	with	with	ADP
fnp-3679	236	5	amyloid	amyloid	NOUN
fnp-3679	236	6	-	-	PUNCT
fnp-3679	236	7	like	like	ADJ
fnp-3679	236	8	oligomers	oligomer	NOUN
fnp-3679	236	9	deposition	deposition	VERB
fnp-3679	236	10	in	in	ADP
fnp-3679	236	11	heart	heart	NOUN
fnp-3679	236	12	failure	failure	NOUN
fnp-3679	236	13	.	.	PUNCT
fnp-3679	237	1	cardiovasc	cardiovasc	PROPN
fnp-3679	237	2	res	re	VERB
fnp-3679	237	3	2014	2014	NUM
fnp-3679	237	4	;	;	PUNCT
fnp-3679	237	5	102:24	102:24	NUM
fnp-3679	237	6	-	-	SYM
fnp-3679	237	7	34	34	NUM
fnp-3679	237	8	.	.	PUNCT
fnp-3679	238	1	https://doi.org/10.1093/cvr/cvu003	https://doi.org/10.1093/cvr/cvu003	PROPN
fnp-3679	238	2	arbustini	arbustini	PROPN
fnp-3679	238	3	e	e	NOUN
fnp-3679	238	4	,	,	PUNCT
fnp-3679	238	5	morbini	morbini	PROPN
fnp-3679	238	6	p	p	NOUN
fnp-3679	238	7	,	,	PUNCT
fnp-3679	238	8	grasso	grasso	PROPN
fnp-3679	238	9	m	m	PROPN
fnp-3679	238	10	,	,	PUNCT
fnp-3679	238	11	fasani	fasani	ADJ
fnp-3679	238	12	r	r	NOUN
fnp-3679	238	13	,	,	PUNCT
fnp-3679	238	14	verga	verga	NOUN
fnp-3679	238	15	l	l	NOUN
fnp-3679	238	16	,	,	PUNCT
fnp-3679	238	17	bellini	bellini	PROPN
fnp-3679	238	18	o	o	NOUN
fnp-3679	238	19	,	,	PUNCT
fnp-3679	238	20	dal	dal	NOUN
fnp-3679	238	21	bello	bello	PROPN
fnp-3679	238	22	b	b	PROPN
fnp-3679	238	23	,	,	PUNCT
fnp-3679	238	24	campana	campana	PROPN
fnp-3679	238	25	c	c	PROPN
fnp-3679	238	26	,	,	PUNCT
fnp-3679	238	27	piccolo	piccolo	NOUN
fnp-3679	238	28	g	g	PROPN
fnp-3679	238	29	,	,	PUNCT
fnp-3679	238	30	febo	febo	NOUN
fnp-3679	238	31	o	o	NOUN
fnp-3679	238	32	,	,	PUNCT
fnp-3679	238	33	opasich	opasich	ADV
fnp-3679	238	34	c	c	NOUN
fnp-3679	238	35	,	,	PUNCT
fnp-3679	238	36	gabazzi	gabazzi	VERB
fnp-3679	238	37	a	a	PRON
fnp-3679	238	38	,	,	PUNCT
fnp-3679	238	39	ferrans	ferran	NOUN
fnp-3679	238	40	vj	vj	PROPN
fnp-3679	238	41	.	.	PROPN
fnp-3679	238	42	restrictive	restrictive	ADJ
fnp-3679	238	43	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	238	44	,	,	PUNCT
fnp-3679	238	45	atrioventricular	atrioventricular	ADJ
fnp-3679	238	46	block	block	NOUN
fnp-3679	238	47	and	and	CCONJ
fnp-3679	238	48	mild	mild	ADJ
fnp-3679	238	49	subclinical	subclinical	ADJ
fnp-3679	238	50	myopathy	myopathy	ADJ
fnp-3679	238	51	in	in	ADP
fnp-3679	238	52	patients	patient	NOUN
fnp-3679	238	53	with	with	ADP
fnp-3679	238	54	desmin	desmin	ADJ
fnp-3679	238	55	-	-	PUNCT
fnp-3679	238	56	immunoractive	immunoractive	ADJ
fnp-3679	238	57	material	material	NOUN
fnp-3679	238	58	deposits	deposit	NOUN
fnp-3679	238	59	.	.	PUNCT
fnp-3679	239	1	j	j	PROPN
fnp-3679	239	2	am	be	AUX
fnp-3679	239	3	coll	coll	PROPN
fnp-3679	239	4	cardiol	cardiol	NOUN
fnp-3679	239	5	1998	1998	NUM
fnp-3679	239	6	;	;	PUNCT
fnp-3679	239	7	3:645	3:645	NUM
fnp-3679	239	8	-	-	SYM
fnp-3679	239	9	53	53	NUM
fnp-3679	239	10	.	.	PUNCT
fnp-3679	240	1	https://doi.org/10.1016/s0735-1097(98)00026-6	https://doi.org/10.1016/s0735-1097(98)00026-6	PROPN
fnp-3679	240	2	becker	becker	PROPN
fnp-3679	240	3	ab	ab	PROPN
fnp-3679	240	4	,	,	PUNCT
fnp-3679	240	5	qian	qian	PROPN
fnp-3679	240	6	j	j	PROPN
fnp-3679	240	7	,	,	PUNCT
fnp-3679	240	8	gelman	gelman	PROPN
fnp-3679	240	9	bb	bb	PROPN
fnp-3679	240	10	,	,	PUNCT
fnp-3679	240	11	yang	yang	PROPN
fnp-3679	240	12	m	m	PROPN
fnp-3679	240	13	,	,	PUNCT
fnp-3679	240	14	bauer	bauer	PROPN
fnp-3679	240	15	p	p	PROPN
fnp-3679	240	16	,	,	PUNCT
fnp-3679	240	17	koeppen	koeppen	ADJ
fnp-3679	240	18	ah	ah	INTJ
fnp-3679	240	19	.	.	PUNCT
fnp-3679	241	1	heart	heart	NOUN
fnp-3679	241	2	and	and	CCONJ
fnp-3679	241	3	nervous	nervous	ADJ
fnp-3679	241	4	system	system	NOUN
fnp-3679	241	5	pathology	pathology	NOUN
fnp-3679	241	6	in	in	ADP
fnp-3679	241	7	compound	compound	NOUN
fnp-3679	241	8	heterozygous	heterozygous	ADJ
fnp-3679	241	9	friedreich	friedreich	NOUN
fnp-3679	241	10	ataxia	ataxia	NOUN
fnp-3679	241	11	.	.	PUNCT
fnp-3679	242	1	j	j	PROPN
fnp-3679	242	2	neuropathol	neuropathol	PROPN
fnp-3679	242	3	exp	exp	PROPN
fnp-3679	242	4	neurol	neurol	PROPN
fnp-3679	242	5	2017	2017	NUM
fnp-3679	242	6	;	;	PUNCT
fnp-3679	242	7	76	76	NUM
fnp-3679	242	8	:	:	PUNCT
fnp-3679	242	9	665	665	NUM
fnp-3679	242	10	-	-	SYM
fnp-3679	242	11	75	75	NUM
fnp-3679	242	12	.	.	PUNCT
fnp-3679	243	1	https://doi.org/10.1093/jnen/nlx047	https://doi.org/10.1093/jnen/nlx047	PROPN
fnp-3679	243	2	bradford	bradford	PROPN
fnp-3679	243	3	mm	mm	PROPN
fnp-3679	243	4	.	.	PUNCT
fnp-3679	244	1	a	a	DET
fnp-3679	244	2	rapid	rapid	ADJ
fnp-3679	244	3	and	and	CCONJ
fnp-3679	244	4	sensitive	sensitive	ADJ
fnp-3679	244	5	method	method	NOUN
fnp-3679	244	6	for	for	ADP
fnp-3679	244	7	the	the	DET
fnp-3679	244	8	quantitation	quantitation	NOUN
fnp-3679	244	9	of	of	ADP
fnp-3679	244	10	microgram	microgram	ADJ
fnp-3679	244	11	quantities	quantity	NOUN
fnp-3679	244	12	of	of	ADP
fnp-3679	244	13	protein	protein	NOUN
fnp-3679	244	14	utilizing	utilize	VERB
fnp-3679	244	15	the	the	DET
fnp-3679	244	16	principle	principle	NOUN
fnp-3679	244	17	of	of	ADP
fnp-3679	244	18	protein	protein	NOUN
fnp-3679	244	19	-	-	PUNCT
fnp-3679	244	20	dye	dye	NOUN
fnp-3679	244	21	binding	binding	NOUN
fnp-3679	244	22	.	.	PUNCT
fnp-3679	245	1	anal	anal	ADJ
fnp-3679	245	2	biochem	biochem	NOUN
fnp-3679	245	3	1976	1976	NUM
fnp-3679	245	4	;	;	PUNCT
fnp-3679	245	5	72:348	72:348	NUM
fnp-3679	245	6	-	-	SYM
fnp-3679	245	7	54	54	NUM
fnp-3679	245	8	.	.	PUNCT
fnp-3679	246	1	https://doi.org/10.1006/abio.1976.9999	https://doi.org/10.1006/abio.1976.9999	PROPN
fnp-3679	246	2	capetanaki	capetanaki	PROPN
fnp-3679	246	3	y	y	PROPN
fnp-3679	246	4	,	,	PUNCT
fnp-3679	246	5	papathanasiou	papathanasiou	NOUN
fnp-3679	246	6	s	s	PROPN
fnp-3679	246	7	,	,	PUNCT
fnp-3679	246	8	diokmetzidou	diokmetzidou	VERB
fnp-3679	246	9	a	a	PRON
fnp-3679	246	10	,	,	PUNCT
fnp-3679	246	11	vatswellas	vatswellas	PROPN
fnp-3679	246	12	g	g	PROPN
fnp-3679	246	13	,	,	PUNCT
fnp-3679	246	14	tsikitis	tsikitis	PROPN
fnp-3679	246	15	m.	m.	NOUN
fnp-3679	246	16	desmin	desmin	NOUN
fnp-3679	246	17	related	relate	VERB
fnp-3679	246	18	disease	disease	NOUN
fnp-3679	246	19	:	:	PUNCT
fnp-3679	246	20	a	a	DET
fnp-3679	246	21	matter	matter	NOUN
fnp-3679	246	22	of	of	ADP
fnp-3679	246	23	cell	cell	NOUN
fnp-3679	246	24	survival	survival	NOUN
fnp-3679	246	25	failure	failure	NOUN
fnp-3679	246	26	.	.	PUNCT
fnp-3679	247	1	curr	curr	PROPN
fnp-3679	247	2	opin	opin	NOUN
fnp-3679	247	3	cell	cell	NOUN
fnp-3679	247	4	biol	biol	NOUN
fnp-3679	247	5	2015	2015	NUM
fnp-3679	247	6	;	;	PUNCT
fnp-3679	247	7	32:113	32:113	NUM
fnp-3679	247	8	-	-	SYM
fnp-3679	247	9	20	20	NUM
fnp-3679	247	10	.	.	PUNCT
fnp-3679	248	1	https://doi.org/10.1016/j.ceb.2015.01.004	https://doi.org/10.1016/j.ceb.2015.01.004	NOUN
fnp-3679	248	2	clemen	cleman	NOUN
fnp-3679	248	3	cs	cs	PROPN
fnp-3679	248	4	,	,	PUNCT
fnp-3679	248	5	fischer	fischer	PROPN
fnp-3679	248	6	d	d	PROPN
fnp-3679	248	7	,	,	PUNCT
fnp-3679	248	8	heimann	heimann	PROPN
fnp-3679	248	9	j	j	PROPN
fnp-3679	248	10	,	,	PUNCT
fnp-3679	248	11	eichinger	eichinger	NOUN
fnp-3679	248	12	l	l	PROPN
fnp-3679	248	13	,	,	PUNCT
fnp-3679	248	14	müller	müller	PROPN
fnp-3679	248	15	cr	cr	PROPN
fnp-3679	248	16	,	,	PUNCT
fnp-3679	248	17	müller	müller	PROPN
fnp-3679	248	18	hd	hd	PROPN
fnp-3679	248	19	,	,	PUNCT
fnp-3679	248	20	goebel	goebel	NOUN
fnp-3679	248	21	hh	hh	PROPN
fnp-3679	248	22	,	,	PUNCT
fnp-3679	248	23	schröder	schröder	PROPN
fnp-3679	248	24	r.	r.	PROPN
fnp-3679	248	25	how	how	SCONJ
fnp-3679	248	26	much	much	ADJ
fnp-3679	248	27	mutant	mutant	ADJ
fnp-3679	248	28	protein	protein	NOUN
fnp-3679	248	29	is	be	AUX
fnp-3679	248	30	needed	need	VERB
fnp-3679	248	31	to	to	PART
fnp-3679	248	32	cause	cause	VERB
fnp-3679	248	33	a	a	DET
fnp-3679	248	34	protein	protein	NOUN
fnp-3679	248	35	aggregate	aggregate	ADJ
fnp-3679	248	36	myopathy	myopathy	ADJ
fnp-3679	248	37	in	in	ADP
fnp-3679	248	38	vivo	vivo	NOUN
fnp-3679	248	39	?	?	PUNCT
fnp-3679	249	1	lessons	lesson	NOUN
fnp-3679	249	2	from	from	ADP
fnp-3679	249	3	an	an	DET
fnp-3679	249	4	exceptional	exceptional	ADJ
fnp-3679	249	5	desminopathy	desminopathy	ADJ
fnp-3679	249	6	.	.	PUNCT
fnp-3679	250	1	hum	hum	PROPN
fnp-3679	250	2	mutat	mutat	PROPN
fnp-3679	250	3	2008	2008	NUM
fnp-3679	250	4	;	;	PUNCT
fnp-3679	250	5	30	30	NUM
fnp-3679	250	6	:	:	PUNCT
fnp-3679	250	7	e490	e490	NUM
fnp-3679	250	8	-	-	PUNCT
fnp-3679	250	9	e499	e499	PROPN
fnp-3679	250	10	.	.	PUNCT
fnp-3679	251	1	https://doi.org/10.1002/humu.20941	https://doi.org/10.1002/humu.20941	NOUN
fnp-3679	251	2	clemen	clemen	PROPN
fnp-3679	251	3	cs	cs	PROPN
fnp-3679	251	4	,	,	PUNCT
fnp-3679	251	5	herrmann	herrmann	PROPN
fnp-3679	251	6	h	h	PROPN
fnp-3679	251	7	,	,	PUNCT
fnp-3679	251	8	strelkov	strelkov	PROPN
fnp-3679	251	9	sv	sv	PROPN
fnp-3679	251	10	,	,	PUNCT
fnp-3679	251	11	schröder	schröder	PROPN
fnp-3679	251	12	r.	r.	PROPN
fnp-3679	251	13	desminopathies	desminopathies	PROPN
fnp-3679	251	14	:	:	PUNCT
fnp-3679	251	15	pathology	pathology	NOUN
fnp-3679	251	16	and	and	CCONJ
fnp-3679	251	17	mechanisms	mechanism	NOUN
fnp-3679	251	18	.	.	PUNCT
fnp-3679	252	1	acta	acta	PROPN
fnp-3679	252	2	neuropathol	neuropathol	PROPN
fnp-3679	252	3	2013	2013	NUM
fnp-3679	252	4	;	;	PUNCT
fnp-3679	252	5	125:47	125:47	NUM
fnp-3679	252	6	-	-	SYM
fnp-3679	252	7	75	75	NUM
fnp-3679	252	8	.	.	PUNCT
fnp-3679	253	1	https://doi.org/10.1007/s00401-012-1057-6	https://doi.org/10.1007/s00401-012-1057-6	NUM
fnp-3679	253	2	condò	condò	PROPN
fnp-3679	253	3	i	i	PROPN
fnp-3679	253	4	,	,	PUNCT
fnp-3679	253	5	ventura	ventura	PROPN
fnp-3679	253	6	n	n	CCONJ
fnp-3679	253	7	,	,	PUNCT
fnp-3679	253	8	malisan	malisan	PROPN
fnp-3679	253	9	f	f	X
fnp-3679	253	10	,	,	PUNCT
fnp-3679	253	11	tomassini	tomassini	PROPN
fnp-3679	253	12	b	b	NOUN
fnp-3679	253	13	,	,	PUNCT
fnp-3679	253	14	testi	testi	PROPN
fnp-3679	253	15	re	re	VERB
fnp-3679	253	16	.	.	PUNCT
fnp-3679	254	1	a	a	DET
fnp-3679	254	2	pool	pool	NOUN
fnp-3679	254	3	of	of	ADP
fnp-3679	254	4	extramitochondrial	extramitochondrial	ADJ
fnp-3679	254	5	frataxin	frataxin	NOUN
fnp-3679	254	6	that	that	PRON
fnp-3679	254	7	promotes	promote	VERB
fnp-3679	254	8	cell	cell	NOUN
fnp-3679	254	9	survival	survival	NOUN
fnp-3679	254	10	.	.	PUNCT
fnp-3679	255	1	j	j	PROPN
fnp-3679	255	2	biol	biol	PROPN
fnp-3679	255	3	chem	chem	NOUN
fnp-3679	255	4	2006	2006	NUM
fnp-3679	255	5	;	;	PUNCT
fnp-3679	255	6	281:16750	281:16750	NUM
fnp-3679	255	7	-	-	SYM
fnp-3679	255	8	6	6	NUM
fnp-3679	255	9	.	.	PUNCT
fnp-3679	256	1	https://doi.org/10.1074/jbc.m511960200	https://doi.org/10.1074/jbc.m511960200	PROPN
fnp-3679	256	2	dalakas	dalakas	PROPN
fnp-3679	256	3	,	,	PUNCT
fnp-3679	256	4	mc	mc	PROPN
fnp-3679	256	5	,	,	PUNCT
fnp-3679	256	6	park	park	PROPN
fnp-3679	256	7	k	k	PROPN
fnp-3679	256	8	-	-	PROPN
fnp-3679	256	9	y	y	PROPN
fnp-3679	256	10	,	,	PUNCT
fnp-3679	256	11	semino	semino	NOUN
fnp-3679	256	12	-	-	PUNCT
fnp-3679	256	13	mora	mora	PROPN
fnp-3679	256	14	c	c	PROPN
fnp-3679	256	15	,	,	PUNCT
fnp-3679	256	16	lee	lee	PROPN
fnp-3679	256	17	,	,	PUNCT
fnp-3679	256	18	hs	hs	PROPN
fnp-3679	256	19	,	,	PUNCT
fnp-3679	256	20	sivakumar	sivakumar	PROPN
fnp-3679	256	21	k	k	PROPN
fnp-3679	256	22	,	,	PUNCT
fnp-3679	256	23	goldfarb	goldfarb	PROPN
fnp-3679	256	24	lg	lg	PROPN
fnp-3679	256	25	.	.	PUNCT
fnp-3679	257	1	desmin	desmin	ADJ
fnp-3679	257	2	myopathy	myopathy	ADJ
fnp-3679	257	3	,	,	PUNCT
fnp-3679	257	4	a	a	DET
fnp-3679	257	5	skeletal	skeletal	ADJ
fnp-3679	257	6	myopathy	myopathy	NOUN
fnp-3679	257	7	with	with	ADP
fnp-3679	257	8	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	257	9	caused	cause	VERB
fnp-3679	257	10	by	by	ADP
fnp-3679	257	11	mutations	mutation	NOUN
fnp-3679	257	12	in	in	ADP
fnp-3679	257	13	the	the	DET
fnp-3679	257	14	desmin	desmin	ADJ
fnp-3679	257	15	gene	gene	NOUN
fnp-3679	257	16	.	.	PUNCT
fnp-3679	258	1	new	new	ADJ
fnp-3679	258	2	engl	engl	PROPN
fnp-3679	258	3	j	j	PROPN
fnp-3679	258	4	med	med	PROPN
fnp-3679	258	5	2000	2000	NUM
fnp-3679	258	6	;	;	PUNCT
fnp-3679	258	7	342:770	342:770	X
fnp-3679	258	8	-	-	SYM
fnp-3679	258	9	80	80	NUM
fnp-3679	258	10	.	.	PUNCT
fnp-3679	259	1	https://doi.org/10.1056/nejm200003163421104	https://doi.org/10.1056/nejm200003163421104	PROPN
fnp-3679	259	2	ghosh	ghosh	PROPN
fnp-3679	259	3	jg	jg	PROPN
fnp-3679	259	4	,	,	PUNCT
fnp-3679	259	5	houck	houck	PROPN
fnp-3679	259	6	sa	sa	PROPN
fnp-3679	259	7	,	,	PUNCT
fnp-3679	259	8	clark	clark	PROPN
fnp-3679	259	9	ji	ji	PROPN
fnp-3679	259	10	.	.	PROPN
fnp-3679	259	11	interactive	interactive	ADJ
fnp-3679	259	12	sequences	sequence	NOUN
fnp-3679	259	13	in	in	ADP
fnp-3679	259	14	the	the	DET
fnp-3679	259	15	stress	stress	NOUN
fnp-3679	259	16	protein	protein	NOUN
fnp-3679	259	17	and	and	CCONJ
fnp-3679	259	18	molecular	molecular	ADJ
fnp-3679	259	19	chaperone	chaperone	NOUN
fnp-3679	259	20	human	human	NOUN
fnp-3679	259	21	αb	αb	PROPN
fnp-3679	259	22	crystallin	crystallin	PROPN
fnp-3679	259	23	recognize	recognize	VERB
fnp-3679	259	24	and	and	CCONJ
fnp-3679	259	25	modulate	modulate	VERB
fnp-3679	259	26	the	the	DET
fnp-3679	259	27	assembly	assembly	NOUN
fnp-3679	259	28	of	of	ADP
fnp-3679	259	29	filaments	filament	NOUN
fnp-3679	259	30	.	.	PUNCT
fnp-3679	260	1	int	int	PROPN
fnp-3679	260	2	j	j	PROPN
fnp-3679	260	3	biochem	biochem	PROPN
fnp-3679	260	4	cell	cell	NOUN
fnp-3679	260	5	biol	biol	PROPN
fnp-3679	260	6	2007	2007	NUM
fnp-3679	260	7	;	;	PUNCT
fnp-3679	260	8	39:1804	39:1804	NUM
fnp-3679	260	9	-	-	SYM
fnp-3679	260	10	15	15	NUM
fnp-3679	260	11	.	.	PUNCT
fnp-3679	261	1	https://doi.org/10.1016/j.biocel.2007.04.027	https://doi.org/10.1016/j.biocel.2007.04.027	AUX
fnp-3679	261	2	goldfarb	goldfarb	PROPN
fnp-3679	261	3	lg	lg	PROPN
fnp-3679	261	4	,	,	PUNCT
fnp-3679	261	5	vicart	vicart	NOUN
fnp-3679	261	6	p	p	NOUN
fnp-3679	261	7	,	,	PUNCT
fnp-3679	261	8	goebel	goebel	NOUN
fnp-3679	261	9	hh	hh	PROPN
fnp-3679	261	10	,	,	PUNCT
fnp-3679	261	11	dalakas	dalakas	PROPN
fnp-3679	261	12	mc	mc	PROPN
fnp-3679	261	13	.	.	PUNCT
fnp-3679	261	14	desmin	desmin	ADJ
fnp-3679	261	15	myopathy	myopathy	ADJ
fnp-3679	261	16	.	.	PUNCT
fnp-3679	262	1	brain	brain	NOUN
fnp-3679	262	2	2004	2004	NUM
fnp-3679	262	3	;	;	PUNCT
fnp-3679	262	4	127(pt	127(pt	NUM
fnp-3679	262	5	4):723	4):723	NUM
fnp-3679	262	6	-	-	SYM
fnp-3679	262	7	34	34	NUM
fnp-3679	262	8	.	.	PUNCT
fnp-3679	263	1	https://doi.org/10.1093/brain/awh033	https://doi.org/10.1093/brain/awh033	PROPN
fnp-3679	263	2	goldfarb	goldfarb	PROPN
fnp-3679	263	3	lg	lg	PROPN
fnp-3679	263	4	,	,	PUNCT
fnp-3679	263	5	dalakas	dalakas	PROPN
fnp-3679	263	6	mc	mc	PROPN
fnp-3679	263	7	.	.	PROPN
fnp-3679	263	8	tragedy	tragedy	NOUN
fnp-3679	263	9	in	in	ADP
fnp-3679	263	10	a	a	DET
fnp-3679	263	11	heartbeat	heartbeat	NOUN
fnp-3679	263	12	:	:	PUNCT
fnp-3679	263	13	malfunctioning	malfunction	VERB
fnp-3679	263	14	desmin	desmin	ADJ
fnp-3679	263	15	causes	cause	VERB
fnp-3679	263	16	skeletal	skeletal	ADJ
fnp-3679	263	17	and	and	CCONJ
fnp-3679	263	18	cardiac	cardiac	ADJ
fnp-3679	263	19	muscle	muscle	NOUN
fnp-3679	263	20	disease	disease	NOUN
fnp-3679	263	21	.	.	PUNCT
fnp-3679	264	1	j	j	PROPN
fnp-3679	264	2	clin	clin	PROPN
fnp-3679	264	3	invest	invest	VERB
fnp-3679	264	4	2009	2009	NUM
fnp-3679	264	5	;	;	PUNCT
fnp-3679	264	6	119:1806	119:1806	NUM
fnp-3679	264	7	-	-	SYM
fnp-3679	264	8	13	13	NUM
fnp-3679	264	9	.	.	PUNCT
fnp-3679	265	1	https://doi.org/10.1172/jci38027	https://doi.org/10.1172/jci38027	PROPN
fnp-3679	265	2	hnia	hnia	PROPN
fnp-3679	265	3	k	k	PROPN
fnp-3679	265	4	,	,	PUNCT
fnp-3679	265	5	rumspacher	rumspacher	PROPN
fnp-3679	265	6	c	c	NOUN
fnp-3679	265	7	,	,	PUNCT
fnp-3679	265	8	vermot	vermot	PROPN
fnp-3679	265	9	j	j	PROPN
fnp-3679	265	10	,	,	PUNCT
fnp-3679	265	11	laporte	laporte	NOUN
fnp-3679	265	12	j.	j.	PROPN
fnp-3679	265	13	desmin	desmin	PROPN
fnp-3679	265	14	in	in	ADP
fnp-3679	265	15	muscle	muscle	NOUN
fnp-3679	265	16	and	and	CCONJ
fnp-3679	265	17	associated	associated	ADJ
fnp-3679	265	18	disease	disease	NOUN
fnp-3679	265	19	:	:	PUNCT
fnp-3679	265	20	beyond	beyond	ADP
fnp-3679	265	21	the	the	DET
fnp-3679	265	22	structural	structural	ADJ
fnp-3679	265	23	function	function	NOUN
fnp-3679	265	24	.	.	PUNCT
fnp-3679	266	1	cell	cell	NOUN
fnp-3679	266	2	tiss	tiss	PROPN
fnp-3679	266	3	res	re	NOUN
fnp-3679	266	4	2015	2015	NUM
fnp-3679	266	5	;	;	PUNCT
fnp-3679	266	6	360:591	360:591	NOUN
fnp-3679	266	7	-	-	SYM
fnp-3679	266	8	608	608	NUM
fnp-3679	266	9	.	.	PUNCT
fnp-3679	267	1	https://doi.org/10.1007/s00441-014-2016-4	https://doi.org/10.1007/s00441-014-2016-4	PROPN
fnp-3679	267	2	kedia	kedia	PROPN
fnp-3679	267	3	n	n	CCONJ
fnp-3679	267	4	,	,	PUNCT
fnp-3679	267	5	arhzaouy	arhzaouy	PROPN
fnp-3679	267	6	k	k	NOUN
fnp-3679	267	7	,	,	PUNCT
fnp-3679	267	8	pittman	pittman	NOUN
fnp-3679	267	9	sk	sk	PROPN
fnp-3679	267	10	,	,	PUNCT
fnp-3679	267	11	sun	sun	PROPN
fnp-3679	267	12	y	y	PROPN
fnp-3679	267	13	,	,	PUNCT
fnp-3679	267	14	batchelor	batchelor	PROPN
fnp-3679	267	15	m	m	PROPN
fnp-3679	267	16	,	,	PUNCT
fnp-3679	267	17	weihl	weihl	PROPN
fnp-3679	267	18	cc	cc	NOUN
fnp-3679	267	19	,	,	PUNCT
fnp-3679	267	20	bieschke	bieschke	PROPN
fnp-3679	267	21	j.	j.	PROPN
fnp-3679	267	22	desmin	desmin	PROPN
fnp-3679	267	23	forms	form	NOUN
fnp-3679	267	24	toxic	toxic	ADJ
fnp-3679	267	25	,	,	PUNCT
fnp-3679	267	26	seeding	seed	VERB
fnp-3679	267	27	-	-	PUNCT
fnp-3679	267	28	competent	competent	ADJ
fnp-3679	267	29	amyloid	amyloid	NOUN
fnp-3679	267	30	aggregates	aggregate	NOUN
fnp-3679	267	31	that	that	PRON
fnp-3679	267	32	persist	persist	VERB
fnp-3679	267	33	in	in	ADP
fnp-3679	267	34	muscle	muscle	NOUN
fnp-3679	267	35	fibers	fiber	NOUN
fnp-3679	267	36	.	.	PUNCT
fnp-3679	268	1	proc	proc	PROPN
fnp-3679	268	2	natl	natl	PROPN
fnp-3679	268	3	acad	acad	PROPN
fnp-3679	268	4	sci	sci	PROPN
fnp-3679	268	5	usa	usa	PROPN
fnp-3679	268	6	2019	2019	NUM
fnp-3679	268	7	;	;	PUNCT
fnp-3679	268	8	116(34):16835	116(34):16835	PROPN
fnp-3679	268	9	-	-	PUNCT
fnp-3679	268	10	4	4	NUM
fnp-3679	268	11	.	.	PUNCT
fnp-3679	268	12	https://doi.org/10.1073/pnas.1908263116	https://doi.org/10.1073/pnas.1908263116	PROPN
fnp-3679	268	13	koeppen	koeppen	ADJ
fnp-3679	268	14	ah	ah	INTJ
fnp-3679	268	15	,	,	PUNCT
fnp-3679	268	16	ramirez	ramirez	PROPN
fnp-3679	268	17	rl	rl	PROPN
fnp-3679	268	18	,	,	PUNCT
fnp-3679	268	19	becker	becker	PROPN
fnp-3679	268	20	ab	ab	PROPN
fnp-3679	268	21	,	,	PUNCT
fnp-3679	268	22	bjork	bjork	PROPN
fnp-3679	268	23	st	st	PROPN
fnp-3679	268	24	,	,	PUNCT
fnp-3679	268	25	levi	levi	PROPN
fnp-3679	268	26	s	s	PROPN
fnp-3679	268	27	,	,	PUNCT
fnp-3679	268	28	santambrogio	santambrogio	PROPN
fnp-3679	268	29	p	p	X
fnp-3679	268	30	,	,	PUNCT
fnp-3679	268	31	parsons	parsons	PROPN
fnp-3679	268	32	pj	pj	PROPN
fnp-3679	268	33	,	,	PUNCT
fnp-3679	268	34	kruger	kruger	PROPN
fnp-3679	268	35	pc	pc	PROPN
fnp-3679	268	36	,	,	PUNCT
fnp-3679	268	37	yang	yang	PROPN
fnp-3679	268	38	kx	kx	PROPN
fnp-3679	268	39	,	,	PUNCT
fnp-3679	268	40	feustel	feustel	PROPN
fnp-3679	268	41	pj	pj	PROPN
fnp-3679	268	42	,	,	PUNCT
fnp-3679	268	43	mazurkiewicz	mazurkiewicz	PROPN
fnp-3679	268	44	je	je	PROPN
fnp-3679	268	45	.	.	PUNCT
fnp-3679	269	1	the	the	DET
fnp-3679	269	2	pathogenesis	pathogenesis	NOUN
fnp-3679	269	3	of	of	ADP
fnp-3679	269	4	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	269	5	in	in	ADP
fnp-3679	269	6	friedreich	friedreich	NOUN
fnp-3679	269	7	ataxia	ataxia	NOUN
fnp-3679	269	8	.	.	PUNCT
fnp-3679	270	1	plos	plos	PROPN
fnp-3679	270	2	one	one	NUM
fnp-3679	270	3	2015	2015	NUM
fnp-3679	270	4	;	;	PUNCT
fnp-3679	270	5	10	10	NUM
fnp-3679	270	6	:	:	PUNCT
fnp-3679	270	7	e116396	e116396	PROPN
fnp-3679	270	8	.	.	PUNCT
fnp-3679	271	1	https://doi.org/10.1371/journal.pone.0116396	https://doi.org/10.1371/journal.pone.0116396	PROPN
fnp-3679	271	2	koeppen	koeppen	PROPN
fnp-3679	271	3	ah	ah	INTJ
fnp-3679	271	4	,	,	PUNCT
fnp-3679	271	5	qian	qian	PROPN
fnp-3679	271	6	j	j	PROPN
fnp-3679	271	7	,	,	PUNCT
fnp-3679	271	8	travis	travis	PROPN
fnp-3679	271	9	am	be	AUX
fnp-3679	271	10	,	,	PUNCT
fnp-3679	271	11	sossei	sossei	VERB
fnp-3679	271	12	ab	ab	PROPN
fnp-3679	271	13	,	,	PUNCT
fnp-3679	271	14	feustel	feustel	PROPN
fnp-3679	271	15	pj	pj	PROPN
fnp-3679	271	16	,	,	PUNCT
fnp-3679	271	17	mazurkiewicz	mazurkiewicz	PROPN
fnp-3679	271	18	je	je	AUX
fnp-3679	271	19	.	.	PUNCT
fnp-3679	271	20	microvascular	microvascular	ADJ
fnp-3679	271	21	pathology	pathology	NOUN
fnp-3679	271	22	in	in	ADP
fnp-3679	271	23	friedreich	friedreich	NOUN
fnp-3679	271	24	cardiomyopathy	cardiomyopathy	ADJ
fnp-3679	271	25	.	.	PUNCT
fnp-3679	272	1	histol	histol	ADJ
fnp-3679	272	2	histopathol	histopathol	NOUN
fnp-3679	272	3	2020	2020	NUM
fnp-3679	272	4	;	;	PUNCT
fnp-3679	272	5	35:39	35:39	NUM
fnp-3679	272	6	-	-	SYM
fnp-3679	272	7	46	46	NUM
fnp-3679	272	8	.	.	PUNCT
fnp-3679	273	1	https://doi.org/10.14670/hh-18-132	https://doi.org/10.14670/hh-18-132	PROPN
fnp-3679	273	2	kruger	kruger	PROPN
fnp-3679	273	3	pc	pc	PROPN
fnp-3679	273	4	,	,	PUNCT
fnp-3679	273	5	yang	yang	PROPN
fnp-3679	273	6	kx	kx	PROPN
fnp-3679	273	7	,	,	PUNCT
fnp-3679	273	8	parsons	parsons	PROPN
fnp-3679	273	9	pj	pj	PROPN
fnp-3679	273	10	,	,	PUNCT
fnp-3679	273	11	becker	becker	PROPN
fnp-3679	273	12	ab	ab	PROPN
fnp-3679	273	13	,	,	PUNCT
fnp-3679	273	14	feustel	feustel	PROPN
fnp-3679	273	15	pj	pj	PROPN
fnp-3679	273	16	,	,	PUNCT
fnp-3679	273	17	koeppen	koeppen	ADJ
fnp-3679	273	18	ah	ah	INTJ
fnp-3679	273	19	.	.	PUNCT
fnp-3679	274	1	abundance	abundance	NOUN
fnp-3679	274	2	and	and	CCONJ
fnp-3679	274	3	significance	significance	NOUN
fnp-3679	274	4	of	of	ADP
fnp-3679	274	5	iron	iron	NOUN
fnp-3679	274	6	,	,	PUNCT
fnp-3679	274	7	zinc	zinc	NOUN
fnp-3679	274	8	,	,	PUNCT
fnp-3679	274	9	copper	copper	NOUN
fnp-3679	274	10	,	,	PUNCT
fnp-3679	274	11	and	and	CCONJ
fnp-3679	274	12	calcium	calcium	NOUN
fnp-3679	274	13	in	in	ADP
fnp-3679	274	14	the	the	DET
fnp-3679	274	15	hearts	heart	NOUN
fnp-3679	274	16	of	of	ADP
fnp-3679	274	17	patients	patient	NOUN
fnp-3679	274	18	with	with	ADP
fnp-3679	274	19	friedreich	friedreich	NOUN
fnp-3679	274	20	ataxia	ataxia	NOUN
fnp-3679	274	21	.	.	PUNCT
fnp-3679	275	1	am	be	AUX
fnp-3679	275	2	j	j	PROPN
fnp-3679	275	3	cardiol	cardiol	NOUN
fnp-3679	275	4	2016	2016	NUM
fnp-3679	275	5	;	;	PUNCT
fnp-3679	275	6	18:127	18:127	NUM
fnp-3679	275	7	-	-	SYM
fnp-3679	275	8	31	31	NUM
fnp-3679	275	9	.	.	PUNCT
fnp-3679	276	1	https://doi.org/10.1016/j.amjcard.2016.04.024	https://doi.org/10.1016/j.amjcard.2016.04.024	VERB
fnp-3679	276	2	perdomini	perdomini	PROPN
fnp-3679	276	3	m	m	PROPN
fnp-3679	276	4	,	,	PUNCT
fnp-3679	276	5	belbellaa	belbellaa	PROPN
fnp-3679	276	6	b	b	PROPN
fnp-3679	276	7	,	,	PUNCT
fnp-3679	276	8	monassier	monassier	PROPN
fnp-3679	276	9	l	l	PROPN
fnp-3679	276	10	,	,	PUNCT
fnp-3679	276	11	reutenauer	reutenauer	NOUN
fnp-3679	276	12	l	l	NOUN
fnp-3679	276	13	,	,	PUNCT
fnp-3679	276	14	messaddeq	messaddeq	PROPN
fnp-3679	276	15	n	n	SYM
fnp-3679	276	16	,	,	PUNCT
fnp-3679	276	17	cartier	cartier	NOUN
fnp-3679	276	18	n	n	CCONJ
fnp-3679	276	19	,	,	PUNCT
fnp-3679	276	20	crystal	crystal	NOUN
fnp-3679	276	21	reg	reg	PROPN
fnp-3679	276	22	,	,	PUNCT
fnp-3679	276	23	aubourg	aubourg	VERB
fnp-3679	276	24	p	p	NOUN
fnp-3679	276	25	,	,	PUNCT
fnp-3679	276	26	puccio	puccio	PROPN
fnp-3679	276	27	h.	h.	PROPN
fnp-3679	276	28	prevention	prevention	PROPN
fnp-3679	276	29	,	,	PUNCT
fnp-3679	276	30	and	and	CCONJ
fnp-3679	276	31	reversal	reversal	NOUN
fnp-3679	276	32	of	of	ADP
fnp-3679	276	33	severe	severe	ADJ
fnp-3679	276	34	mitochondrial	mitochondrial	ADJ
fnp-3679	276	35	cardiomyopathy	cardiomyopathy	NOUN
fnp-3679	276	36	by	by	ADP
fnp-3679	276	37	gene	gene	NOUN
fnp-3679	276	38	therapy	therapy	NOUN
fnp-3679	276	39	in	in	ADP
fnp-3679	276	40	a	a	DET
fnp-3679	276	41	mouse	mouse	NOUN
fnp-3679	276	42	model	model	NOUN
fnp-3679	276	43	of	of	ADP
fnp-3679	276	44	friedreich	friedreich	PROPN
fnp-3679	276	45	’s	’s	PART
fnp-3679	276	46	ataxia	ataxia	NOUN
fnp-3679	276	47	.	.	PUNCT
fnp-3679	277	1	nat	nat	PROPN
fnp-3679	277	2	med	med	PROPN
fnp-3679	277	3	2014	2014	NUM
fnp-3679	277	4	;	;	PUNCT
fnp-3679	277	5	20:542	20:542	NUM
fnp-3679	277	6	-	-	SYM
fnp-3679	277	7	7	7	NUM
fnp-3679	277	8	.	.	PUNCT
fnp-3679	278	1	https://doi.org/10.1038/nm.3510	https://doi.org/10.1038/nm.3510	PROPN
fnp-3679	278	2	ramirez	ramirez	PROPN
fnp-3679	278	3	rl	rl	PROPN
fnp-3679	278	4	,	,	PUNCT
fnp-3679	278	5	qian	qian	PROPN
fnp-3679	278	6	j	j	PROPN
fnp-3679	278	7	,	,	PUNCT
fnp-3679	278	8	santambrogio	santambrogio	PROPN
fnp-3679	278	9	p	p	X
fnp-3679	278	10	,	,	PUNCT
fnp-3679	278	11	levi	levi	PROPN
fnp-3679	278	12	s	s	PROPN
fnp-3679	278	13	,	,	PUNCT
fnp-3679	278	14	koeppen	koeppen	ADJ
fnp-3679	278	15	ah	ah	INTJ
fnp-3679	278	16	.	.	PUNCT
fnp-3679	279	1	relation	relation	NOUN
fnp-3679	279	2	of	of	ADP
fnp-3679	279	3	cytosolic	cytosolic	ADJ
fnp-3679	279	4	iron	iron	NOUN
fnp-3679	279	5	excess	excess	NOUN
fnp-3679	279	6	to	to	ADP
fnp-3679	279	7	the	the	DET
fnp-3679	279	8	cardiomyopathy	cardiomyopathy	NOUN
fnp-3679	279	9	of	of	ADP
fnp-3679	279	10	friedreich	friedreich	NOUN
fnp-3679	279	11	's	's	PART
fnp-3679	279	12	ataxia	ataxia	NOUN
fnp-3679	279	13	.	.	PUNCT
fnp-3679	280	1	am	be	AUX
fnp-3679	280	2	j	j	PROPN
fnp-3679	280	3	cardiol	cardiol	NOUN
fnp-3679	280	4	2012	2012	NUM
fnp-3679	280	5	;	;	PUNCT
fnp-3679	280	6	110:1820	110:1820	NUM
fnp-3679	280	7	-	-	SYM
fnp-3679	280	8	7	7	NUM
fnp-3679	280	9	.	.	PUNCT
fnp-3679	281	1	https://doi.org/10.1016/j.amjcard.2012.08.018	https://doi.org/10.1016/j.amjcard.2012.08.018	PROPN
fnp-3679	281	2	russell	russell	PROPN
fnp-3679	281	3	ds	ds	PROPN
fnp-3679	281	4	.	.	PROPN
fnp-3679	281	5	myocarditis	myocarditis	PROPN
fnp-3679	281	6	in	in	ADP
fnp-3679	281	7	friedreich	friedreich	PROPN
fnp-3679	281	8	’s	’s	PART
fnp-3679	281	9	ataxia	ataxia	NOUN
fnp-3679	281	10	.	.	PUNCT
fnp-3679	282	1	j	j	PROPN
fnp-3679	282	2	path	path	PROPN
fnp-3679	282	3	bact	bact	PROPN
fnp-3679	282	4	1946	1946	NUM
fnp-3679	282	5	;	;	PUNCT
fnp-3679	282	6	63:739	63:739	NUM
fnp-3679	282	7	-	-	SYM
fnp-3679	282	8	48	48	NUM
fnp-3679	282	9	.	.	PUNCT
fnp-3679	283	1	https://doi.org/10.1002/path.1700580414	https://doi.org/10.1002/path.1700580414	NOUN
fnp-3679	283	2	sharma	sharma	PROPN
fnp-3679	283	3	s	s	PROPN
fnp-3679	283	4	,	,	PUNCT
fnp-3679	283	5	conover	conover	PROPN
fnp-3679	283	6	gm	gm	PROPN
fnp-3679	283	7	,	,	PUNCT
fnp-3679	283	8	elliott	elliott	PROPN
fnp-3679	283	9	jl	jl	PROPN
fnp-3679	283	10	,	,	PUNCT
fnp-3679	283	11	der	der	NOUN
fnp-3679	283	12	perng	perng	VERB
fnp-3679	283	13	m	m	PROPN
fnp-3679	283	14	,	,	PUNCT
fnp-3679	283	15	herrmann	herrmann	PROPN
fnp-3679	283	16	h	h	PROPN
fnp-3679	283	17	,	,	PUNCT
fnp-3679	283	18	quinlan	quinlan	PROPN
fnp-3679	283	19	ra	ra	PROPN
fnp-3679	283	20	.	.	PUNCT
fnp-3679	284	1	αb	αb	PROPN
fnp-3679	284	2	-	-	PUNCT
fnp-3679	284	3	crystallin	crystallin	PROPN
fnp-3679	284	4	is	be	AUX
fnp-3679	284	5	a	a	DET
fnp-3679	284	6	sensor	sensor	NOUN
fnp-3679	284	7	for	for	ADP
fnp-3679	284	8	assembly	assembly	NOUN
fnp-3679	284	9	intermediates	intermediate	NOUN
fnp-3679	284	10	and	and	CCONJ
fnp-3679	284	11	for	for	ADP
fnp-3679	284	12	the	the	DET
fnp-3679	284	13	subunit	subunit	NOUN
fnp-3679	284	14	topology	topology	NOUN
fnp-3679	284	15	of	of	ADP
fnp-3679	284	16	desmin	desmin	ADJ
fnp-3679	284	17	intermediate	intermediate	ADJ
fnp-3679	284	18	filaments	filament	NOUN
fnp-3679	284	19	.	.	PUNCT
fnp-3679	285	1	cell	cell	NOUN
fnp-3679	285	2	stress	stress	NOUN
fnp-3679	285	3	chaperones	chaperone	NOUN
fnp-3679	285	4	2017	2017	NUM
fnp-3679	285	5	;	;	PUNCT
fnp-3679	285	6	22:613	22:613	NUM
fnp-3679	285	7	-	-	SYM
fnp-3679	285	8	26	26	NUM
fnp-3679	285	9	.	.	PUNCT
fnp-3679	286	1	https://doi.org/10.1007/s12192-017-0788-7	https://doi.org/10.1007/s12192-017-0788-7	PRON
fnp-3679	286	2	uniprot	uniprot	ADJ
fnp-3679	286	3	:	:	PUNCT
fnp-3679	286	4	the	the	DET
fnp-3679	286	5	universal	universal	ADJ
fnp-3679	286	6	protein	protein	NOUN
fnp-3679	286	7	knowledge	knowledge	NOUN
fnp-3679	286	8	base	base	NOUN
fnp-3679	286	9	.	.	PUNCT
fnp-3679	287	1	nucleic	nucleic	ADJ
fnp-3679	287	2	acids	acid	NOUN
fnp-3679	287	3	res	re	NOUN
fnp-3679	287	4	2021	2021	NUM
fnp-3679	287	5	;	;	PUNCT
fnp-3679	287	6	49(d1):d480	49(d1):d480	NUM
fnp-3679	287	7	-	-	SYM
fnp-3679	287	8	d489	d489	PROPN
fnp-3679	287	9	.	.	PUNCT
fnp-3679	288	1	https://doi.org/10.1093/nar/gkaa1100	https://doi.org/10.1093/nar/gkaa1100	PROPN
fnp-3679	288	2	uniprot	uniprot	PROPN
fnp-3679	288	3	.	.	PUNCT
fnp-3679	289	1	biogrid	biogrid	ADJ
fnp-3679	289	2	biological	biological	ADJ
fnp-3679	289	3	general	general	ADJ
fnp-3679	289	4	repository	repository	NOUN
fnp-3679	289	5	for	for	ADP
fnp-3679	289	6	interaction	interaction	NOUN
fnp-3679	289	7	datasets	dataset	NOUN
fnp-3679	289	8	2021	2021	NUM
fnp-3679	289	9	.	.	PUNCT
fnp-3679	290	1	https://doi.org/10.25504/fairsharing.9d5f5r	https://doi.org/10.25504/fairsharing.9d5f5r	PROPN
fnp-3679	290	2	yue	yue	PROPN
fnp-3679	290	3	l	l	PROPN
fnp-3679	290	4	,	,	PUNCT
fnp-3679	290	5	sam	sam	PROPN
fnp-3679	290	6	c	c	PROPN
fnp-3679	290	7	,	,	PUNCT
fnp-3679	290	8	arora	arora	PROPN
fnp-3679	290	9	n	n	CCONJ
fnp-3679	290	10	,	,	PUNCT
fnp-3679	290	11	winkler	winkler	PROPN
fnp-3679	290	12	dfh	dfh	PROPN
fnp-3679	290	13	,	,	PUNCT
fnp-3679	290	14	pelech	pelech	NOUN
fnp-3679	290	15	s.	s.	PROPN
fnp-3679	290	16	antibody	antibody	NOUN
fnp-3679	290	17	microarray	microarray	NOUN
fnp-3679	290	18	and	and	CCONJ
fnp-3679	290	19	immunoblotting	immunoblotte	VERB
fnp-3679	290	20	analyses	analysis	NOUN
fnp-3679	290	21	of	of	ADP
fnp-3679	290	22	the	the	DET
fnp-3679	290	23	egf	egf	PROPN
fnp-3679	290	24	signaling	signal	VERB
fnp-3679	290	25	phosphorylation	phosphorylation	NOUN
fnp-3679	290	26	network	network	NOUN
fnp-3679	290	27	in	in	ADP
fnp-3679	290	28	human	human	ADJ
fnp-3679	290	29	a431	a431	PROPN
fnp-3679	290	30	epidermoid	epidermoid	ADJ
fnp-3679	290	31	carcinoma	carcinoma	NOUN
fnp-3679	290	32	cells	cell	NOUN
fnp-3679	290	33	.	.	PUNCT
fnp-3679	291	1	clin	clin	PROPN
fnp-3679	291	2	proteom	proteom	PROPN
fnp-3679	291	3	bioinformat	bioinformat	PROPN
fnp-3679	291	4	2017	2017	NUM
fnp-3679	291	5	;	;	PUNCT
fnp-3679	291	6	2:1	2:1	NUM
fnp-3679	291	7	-	-	SYM
fnp-3679	291	8	10	10	NUM
fnp-3679	291	9	.	.	PUNCT
fnp-3679	292	1	https://doi.org/10.15761/cpb.1000119	https://doi.org/10.15761/cpb.1000119	PROPN
fnp-3679	292	2	yue	yue	PROPN
fnp-3679	292	3	l	l	PROPN
fnp-3679	292	4	,	,	PUNCT
fnp-3679	292	5	pelech	pelech	PROPN
fnp-3679	292	6	s.	s.	PROPN
fnp-3679	292	7	application	application	NOUN
fnp-3679	292	8	of	of	ADP
fnp-3679	292	9	high	high	ADJ
fnp-3679	292	10	content	content	NOUN
fnp-3679	292	11	antibody	antibody	NOUN
fnp-3679	292	12	microarrays	microarray	VERB
fnp-3679	292	13	for	for	ADP
fnp-3679	292	14	biomarker	biomarker	NOUN
fnp-3679	292	15	discovery	discovery	NOUN
fnp-3679	292	16	and	and	CCONJ
fnp-3679	292	17	tracking	track	VERB
fnp-3679	292	18	cellular	cellular	ADJ
fnp-3679	292	19	signaling	signaling	NOUN
fnp-3679	292	20	.	.	PUNCT
fnp-3679	293	1	adv	adv	PROPN
fnp-3679	293	2	proteom	proteom	PROPN
fnp-3679	293	3	bioinformat	bioinformat	NOUN
fnp-3679	293	4	2018:1	2018:1	NUM
fnp-3679	293	5	-	-	SYM
fnp-3679	293	6	24	24	NUM
fnp-3679	293	7	.	.	PUNCT
fnp-3679	294	1	https://doi.org/10.29011/apbi-107.100007	https://doi.org/10.29011/apbi-107.100007	PROPN
fnp-3679	294	2	copyright	copyright	NOUN
fnp-3679	294	3	:	:	PUNCT
fnp-3679	294	4	©	©	PROPN
fnp-3679	294	5	2021	2021	NUM
fnp-3679	294	6	the	the	DET
fnp-3679	294	7	author(s	author(s	NOUN
fnp-3679	294	8	)	)	PUNCT
fnp-3679	294	9	.	.	PUNCT
fnp-3679	295	1	this	this	PRON
fnp-3679	295	2	is	be	AUX
fnp-3679	295	3	an	an	DET
fnp-3679	295	4	open	open	ADJ
fnp-3679	295	5	access	access	NOUN
fnp-3679	295	6	article	article	NOUN
fnp-3679	295	7	distributed	distribute	VERB
fnp-3679	295	8	under	under	ADP
fnp-3679	295	9	the	the	DET
fnp-3679	295	10	terms	term	NOUN
fnp-3679	295	11	of	of	ADP
fnp-3679	295	12	the	the	DET
fnp-3679	295	13	creative	creative	ADJ
fnp-3679	295	14	commons	common	NOUN
fnp-3679	295	15	attribution	attribution	NOUN
fnp-3679	295	16	4.0	4.0	NUM
fnp-3679	295	17	international	international	ADJ
fnp-3679	295	18	license	license	NOUN
fnp-3679	295	19	(	(	PUNCT
fnp-3679	295	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3679	295	21	)	)	PUNCT
fnp-3679	295	22	,	,	PUNCT
fnp-3679	295	23	which	which	PRON
fnp-3679	295	24	permits	permit	VERB
fnp-3679	295	25	unrestricted	unrestricted	ADJ
fnp-3679	295	26	use	use	NOUN
fnp-3679	295	27	,	,	PUNCT
fnp-3679	295	28	distribution	distribution	NOUN
fnp-3679	295	29	,	,	PUNCT
fnp-3679	295	30	and	and	CCONJ
fnp-3679	295	31	reproduction	reproduction	NOUN
fnp-3679	295	32	in	in	ADP
fnp-3679	295	33	any	any	DET
fnp-3679	295	34	medium	medium	NOUN
fnp-3679	295	35	,	,	PUNCT
fnp-3679	295	36	provided	provide	VERB
fnp-3679	295	37	the	the	DET
fnp-3679	295	38	original	original	ADJ
fnp-3679	295	39	author	author	NOUN
fnp-3679	295	40	and	and	CCONJ
fnp-3679	295	41	source	source	NOUN
fnp-3679	295	42	are	be	AUX
fnp-3679	295	43	credited	credit	VERB
fnp-3679	295	44	,	,	PUNCT
fnp-3679	295	45	a	a	DET
fnp-3679	295	46	link	link	NOUN
fnp-3679	295	47	to	to	ADP
fnp-3679	295	48	the	the	DET
fnp-3679	295	49	creative	creative	ADJ
fnp-3679	295	50	commons	common	NOUN
fnp-3679	295	51	license	license	NOUN
fnp-3679	295	52	is	be	AUX
fnp-3679	295	53	provided	provide	VERB
fnp-3679	295	54	,	,	PUNCT
fnp-3679	295	55	and	and	CCONJ
fnp-3679	295	56	any	any	DET
fnp-3679	295	57	changes	change	NOUN
fnp-3679	295	58	are	be	AUX
fnp-3679	295	59	indicated	indicate	VERB
fnp-3679	295	60	.	.	PUNCT
fnp-3679	296	1	the	the	DET
fnp-3679	296	2	creative	creative	ADJ
fnp-3679	296	3	commons	common	NOUN
fnp-3679	296	4	public	public	ADJ
fnp-3679	296	5	domain	domain	NOUN
fnp-3679	296	6	dedication	dedication	NOUN
fnp-3679	296	7	waiver	waiver	NOUN
fnp-3679	296	8	(	(	PUNCT
fnp-3679	296	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3679	296	10	)	)	PUNCT
fnp-3679	296	11	applies	apply	VERB
fnp-3679	296	12	to	to	ADP
fnp-3679	296	13	the	the	DET
fnp-3679	296	14	data	datum	NOUN
fnp-3679	296	15	made	make	VERB
fnp-3679	296	16	available	available	ADJ
fnp-3679	296	17	in	in	ADP
fnp-3679	296	18	this	this	DET
fnp-3679	296	19	article	article	NOUN
fnp-3679	296	20	,	,	PUNCT
fnp-3679	296	21	unless	unless	SCONJ
fnp-3679	296	22	otherwise	otherwise	ADV
fnp-3679	296	23	stated	state	VERB
fnp-3679	296	24	.	.	PUNCT
