id	sid	tid	token	lemma	pos
fnp-3766	1	1	soluble	soluble	ADJ
fnp-3766	1	2	brain	brain	NOUN
fnp-3766	1	3	homogenates	homogenate	NOUN
fnp-3766	1	4	from	from	ADP
fnp-3766	1	5	diverse	diverse	ADJ
fnp-3766	1	6	human	human	ADJ
fnp-3766	1	7	and	and	CCONJ
fnp-3766	1	8	mouse	mouse	NOUN
fnp-3766	1	9	sources	source	NOUN
fnp-3766	1	10	preferentially	preferentially	ADV
fnp-3766	1	11	seed	seed	VERB
fnp-3766	1	12	diffuse	diffuse	NOUN
fnp-3766	1	13	aβ	aβ	NOUN
fnp-3766	1	14	plaque	plaque	NOUN
fnp-3766	1	15	pathology	pathology	NOUN
fnp-3766	1	16	when	when	SCONJ
fnp-3766	1	17	injected	inject	VERB
fnp-3766	1	18	into	into	ADP
fnp-3766	1	19	newborn	newborn	ADJ
fnp-3766	1	20	mouse	mouse	NOUN
fnp-3766	1	21	hosts	host	NOUN
fnp-3766	1	22	feel	feel	VERB
fnp-3766	1	23	free	free	ADJ
fnp-3766	1	24	to	to	PART
fnp-3766	1	25	add	add	VERB
fnp-3766	1	26	comments	comment	NOUN
fnp-3766	1	27	by	by	ADP
fnp-3766	1	28	clicking	click	VERB
fnp-3766	1	29	these	these	DET
fnp-3766	1	30	icons	icon	NOUN
fnp-3766	1	31	on	on	ADP
fnp-3766	1	32	the	the	DET
fnp-3766	1	33	sidebar	sidebar	NOUN
fnp-3766	1	34	free	free	ADJ
fnp-3766	1	35	neuropathology	neuropathology	NOUN
fnp-3766	1	36	3:9	3:9	NUM
fnp-3766	1	37	(	(	PUNCT
fnp-3766	1	38	2022	2022	NUM
fnp-3766	1	39	)	)	PUNCT
fnp-3766	1	40	original	original	ADJ
fnp-3766	1	41	paper	paper	NOUN
fnp-3766	1	42	soluble	soluble	ADJ
fnp-3766	1	43	brain	brain	NOUN
fnp-3766	1	44	homogenates	homogenate	NOUN
fnp-3766	1	45	from	from	ADP
fnp-3766	1	46	diverse	diverse	ADJ
fnp-3766	1	47	human	human	ADJ
fnp-3766	1	48	and	and	CCONJ
fnp-3766	1	49	mouse	mouse	NOUN
fnp-3766	1	50	sources	source	NOUN
fnp-3766	1	51	preferentially	preferentially	ADV
fnp-3766	1	52	seed	seed	VERB
fnp-3766	1	53	diffuse	diffuse	NOUN
fnp-3766	1	54	aβ	aβ	NOUN
fnp-3766	1	55	plaque	plaque	NOUN
fnp-3766	1	56	pathology	pathology	NOUN
fnp-3766	1	57	when	when	SCONJ
fnp-3766	1	58	injected	inject	VERB
fnp-3766	1	59	into	into	ADP
fnp-3766	1	60	newborn	newborn	ADJ
fnp-3766	1	61	mouse	mouse	NOUN
fnp-3766	1	62	hosts	host	NOUN
fnp-3766	1	63	brenda	brenda	PROPN
fnp-3766	1	64	d.	d.	PROPN
fnp-3766	1	65	moore1,2,3	moore1,2,3	PROPN
fnp-3766	1	66	,	,	PUNCT
fnp-3766	1	67	yona	yona	PROPN
fnp-3766	1	68	levites1,2,3	levites1,2,3	PROPN
fnp-3766	1	69	,	,	PUNCT
fnp-3766	1	70	guilian	guilian	PROPN
fnp-3766	1	71	xu1,2,3	xu1,2,3	PROPN
fnp-3766	1	72	,	,	PUNCT
fnp-3766	1	73	hailey	hailey	PROPN
fnp-3766	1	74	hampton1,2	hampton1,2	PROPN
fnp-3766	1	75	,	,	PUNCT
fnp-3766	1	76	munir	munir	PROPN
fnp-3766	1	77	f.	f.	PROPN
fnp-3766	1	78	adamo1,2	adamo1,2	PROPN
fnp-3766	1	79	,	,	PUNCT
fnp-3766	1	80	cara	cara	PROPN
fnp-3766	1	81	l.	l.	PROPN
fnp-3766	1	82	croft1,2,3	croft1,2,3	PROPN
fnp-3766	1	83	,	,	PUNCT
fnp-3766	1	84	hunter	hunter	NOUN
fnp-3766	1	85	s.	s.	PROPN
fnp-3766	1	86	futch1,2	futch1,2	PROPN
fnp-3766	1	87	,	,	PUNCT
fnp-3766	1	88	corey	corey	PROPN
fnp-3766	1	89	moran1,2	moran1,2	PROPN
fnp-3766	1	90	,	,	PUNCT
fnp-3766	1	91	susan	susan	PROPN
fnp-3766	1	92	fromholt1,2	fromholt1,2	PROPN
fnp-3766	1	93	,	,	PUNCT
fnp-3766	1	94	christopher	christopher	PROPN
fnp-3766	1	95	janus1,2,3	janus1,2,3	PROPN
fnp-3766	1	96	,	,	PUNCT
fnp-3766	1	97	stefan	stefan	PROPN
fnp-3766	1	98	prokop2,3,4,5	prokop2,3,4,5	PROPN
fnp-3766	1	99	,	,	PUNCT
fnp-3766	1	100	dennis	dennis	PROPN
fnp-3766	1	101	dickson6	dickson6	PROPN
fnp-3766	1	102	,	,	PUNCT
fnp-3766	1	103	jada	jada	PROPN
fnp-3766	1	104	lewis1,2,3	lewis1,2,3	PROPN
fnp-3766	1	105	,	,	PUNCT
fnp-3766	1	106	benoit	benoit	PROPN
fnp-3766	1	107	i.	i.	PROPN
fnp-3766	1	108	giasson1,2,3	giasson1,2,3	PROPN
fnp-3766	1	109	,	,	PUNCT
fnp-3766	1	110	todd	todd	PROPN
fnp-3766	1	111	e.	e.	PROPN
fnp-3766	1	112	golde1,2,3,7	golde1,2,3,7	PROPN
fnp-3766	1	113	,	,	PUNCT
fnp-3766	1	114	david	david	PROPN
fnp-3766	1	115	r.	r.	PROPN
fnp-3766	1	116	borchelt1,2,3	borchelt1,2,3	PROPN
fnp-3766	1	117	1	1	NUM
fnp-3766	1	118	department	department	NOUN
fnp-3766	1	119	of	of	ADP
fnp-3766	1	120	neuroscience	neuroscience	NOUN
fnp-3766	1	121	,	,	PUNCT
fnp-3766	1	122	college	college	NOUN
fnp-3766	1	123	of	of	ADP
fnp-3766	1	124	medicine	medicine	NOUN
fnp-3766	1	125	,	,	PUNCT
fnp-3766	1	126	university	university	PROPN
fnp-3766	1	127	of	of	ADP
fnp-3766	1	128	florida	florida	PROPN
fnp-3766	1	129	,	,	PUNCT
fnp-3766	1	130	gainesville	gainesville	PROPN
fnp-3766	1	131	,	,	PUNCT
fnp-3766	1	132	fl	fl	PROPN
fnp-3766	1	133	32610	32610	NUM
fnp-3766	1	134	,	,	PUNCT
fnp-3766	1	135	usa	usa	PROPN
fnp-3766	1	136	2	2	NUM
fnp-3766	1	137	center	center	NOUN
fnp-3766	1	138	for	for	ADP
fnp-3766	1	139	translational	translational	ADJ
fnp-3766	1	140	research	research	NOUN
fnp-3766	1	141	in	in	ADP
fnp-3766	1	142	neurodegenerative	neurodegenerative	ADJ
fnp-3766	1	143	disease	disease	NOUN
fnp-3766	1	144	,	,	PUNCT
fnp-3766	1	145	college	college	NOUN
fnp-3766	1	146	of	of	ADP
fnp-3766	1	147	medicine	medicine	NOUN
fnp-3766	1	148	,	,	PUNCT
fnp-3766	1	149	university	university	PROPN
fnp-3766	1	150	of	of	ADP
fnp-3766	1	151	florida	florida	PROPN
fnp-3766	1	152	,	,	PUNCT
fnp-3766	1	153	gainesville	gainesville	PROPN
fnp-3766	1	154	,	,	PUNCT
fnp-3766	1	155	fl	fl	PROPN
fnp-3766	1	156	32610	32610	NUM
fnp-3766	1	157	,	,	PUNCT
fnp-3766	1	158	usa	usa	PROPN
fnp-3766	1	159	3	3	NUM
fnp-3766	1	160	mcknight	mcknight	PROPN
fnp-3766	1	161	brain	brain	PROPN
fnp-3766	1	162	institute	institute	PROPN
fnp-3766	1	163	,	,	PUNCT
fnp-3766	1	164	college	college	NOUN
fnp-3766	1	165	of	of	ADP
fnp-3766	1	166	medicine	medicine	NOUN
fnp-3766	1	167	,	,	PUNCT
fnp-3766	1	168	university	university	PROPN
fnp-3766	1	169	of	of	ADP
fnp-3766	1	170	florida	florida	PROPN
fnp-3766	1	171	,	,	PUNCT
fnp-3766	1	172	gainesville	gainesville	PROPN
fnp-3766	1	173	,	,	PUNCT
fnp-3766	1	174	fl	fl	PROPN
fnp-3766	1	175	32610	32610	NUM
fnp-3766	1	176	,	,	PUNCT
fnp-3766	1	177	usa	usa	PROPN
fnp-3766	1	178	4	4	NUM
fnp-3766	1	179	department	department	NOUN
fnp-3766	1	180	of	of	ADP
fnp-3766	1	181	pathology	pathology	PROPN
fnp-3766	1	182	,	,	PUNCT
fnp-3766	1	183	university	university	PROPN
fnp-3766	1	184	of	of	ADP
fnp-3766	1	185	florida	florida	PROPN
fnp-3766	1	186	,	,	PUNCT
fnp-3766	1	187	gainesville	gainesville	PROPN
fnp-3766	1	188	,	,	PUNCT
fnp-3766	1	189	fl	fl	PROPN
fnp-3766	1	190	32610	32610	NUM
fnp-3766	1	191	,	,	PUNCT
fnp-3766	1	192	usa	usa	PROPN
fnp-3766	1	193	5	5	NUM
fnp-3766	1	194	fixel	fixel	PROPN
fnp-3766	1	195	institute	institute	NOUN
fnp-3766	1	196	for	for	ADP
fnp-3766	1	197	neurological	neurological	ADJ
fnp-3766	1	198	diseases	disease	NOUN
fnp-3766	1	199	,	,	PUNCT
fnp-3766	1	200	university	university	NOUN
fnp-3766	1	201	of	of	ADP
fnp-3766	1	202	florida	florida	PROPN
fnp-3766	1	203	,	,	PUNCT
fnp-3766	1	204	gainesville	gainesville	PROPN
fnp-3766	1	205	,	,	PUNCT
fnp-3766	1	206	fl	fl	PROPN
fnp-3766	1	207	32610	32610	NUM
fnp-3766	1	208	,	,	PUNCT
fnp-3766	1	209	usa	usa	PROPN
fnp-3766	1	210	6	6	NUM
fnp-3766	1	211	department	department	NOUN
fnp-3766	1	212	of	of	ADP
fnp-3766	1	213	neuroscience	neuroscience	NOUN
fnp-3766	1	214	,	,	PUNCT
fnp-3766	1	215	mayo	mayo	NOUN
fnp-3766	1	216	clinic	clinic	PROPN
fnp-3766	1	217	,	,	PUNCT
fnp-3766	1	218	jacksonville	jacksonville	PROPN
fnp-3766	1	219	,	,	PUNCT
fnp-3766	1	220	fl	fl	PROPN
fnp-3766	1	221	,	,	PUNCT
fnp-3766	1	222	usa	usa	PROPN
fnp-3766	1	223	7	7	NUM
fnp-3766	1	224	department	department	PROPN
fnp-3766	1	225	of	of	ADP
fnp-3766	1	226	neurology	neurology	NOUN
fnp-3766	1	227	,	,	PUNCT
fnp-3766	1	228	college	college	NOUN
fnp-3766	1	229	of	of	ADP
fnp-3766	1	230	medicine	medicine	NOUN
fnp-3766	1	231	,	,	PUNCT
fnp-3766	1	232	university	university	PROPN
fnp-3766	1	233	of	of	ADP
fnp-3766	1	234	florida	florida	PROPN
fnp-3766	1	235	,	,	PUNCT
fnp-3766	1	236	gainesville	gainesville	NOUN
fnp-3766	1	237	fl	fl	NUM
fnp-3766	1	238	32610	32610	NUM
fnp-3766	1	239	,	,	PUNCT
fnp-3766	1	240	usa	usa	PROPN
fnp-3766	1	241	corresponding	corresponding	PROPN
fnp-3766	1	242	author	author	NOUN
fnp-3766	1	243	:	:	PUNCT
fnp-3766	1	244	brenda	brenda	PROPN
fnp-3766	1	245	d.	d.	PROPN
fnp-3766	1	246	moore	moore	PROPN
fnp-3766	1	247	·	·	PROPN
fnp-3766	1	248	1275	1275	NUM
fnp-3766	1	249	center	center	PROPN
fnp-3766	1	250	dr	dr	PROPN
fnp-3766	1	251	·	·	PROPN
fnp-3766	1	252	po	po	PROPN
fnp-3766	1	253	box	box	PROPN
fnp-3766	1	254	100159	100159	NUM
fnp-3766	1	255	,	,	PUNCT
fnp-3766	1	256	352	352	NUM
fnp-3766	1	257	-	-	PUNCT
fnp-3766	1	258	273	273	NUM
fnp-3766	1	259	-	-	PUNCT
fnp-3766	1	260	7868	7868	NUM
fnp-3766	1	261	·	·	PUNCT
fnp-3766	1	262	gainesville	gainesville	NOUN
fnp-3766	1	263	,	,	PUNCT
fnp-3766	1	264	fl	fl	PROPN
fnp-3766	1	265	32610	32610	NUM
fnp-3766	1	266	·	·	PUNCT
fnp-3766	1	267	usa	usa	PROPN
fnp-3766	1	268	brendar@ufl.edu	brendar@ufl.edu	PROPN
fnp-3766	1	269	submitted	submit	VERB
fnp-3766	1	270	:	:	PUNCT
fnp-3766	1	271	18	18	NUM
fnp-3766	1	272	january	january	PROPN
fnp-3766	1	273	2022	2022	NUM
fnp-3766	1	274	accepted	accept	VERB
fnp-3766	1	275	:	:	PUNCT
fnp-3766	1	276	28	28	NUM
fnp-3766	1	277	february	february	PROPN
fnp-3766	1	278	2022	2022	NUM
fnp-3766	1	279	copyedited	copyedit	VERB
fnp-3766	1	280	by	by	ADP
fnp-3766	1	281	:	:	PUNCT
fnp-3766	1	282	henry	henry	PROPN
fnp-3766	1	283	robbert	robbert	PROPN
fnp-3766	1	284	published	publish	VERB
fnp-3766	1	285	:	:	PUNCT
fnp-3766	1	286	23	23	NUM
fnp-3766	1	287	march	march	NOUN
fnp-3766	1	288	2022	2022	NUM
fnp-3766	1	289	https://doi.org/10.17879/freeneuropathology-2022-3766	https://doi.org/10.17879/freeneuropathology-2022-3766	ADP
fnp-3766	1	290	additional	additional	ADJ
fnp-3766	1	291	resources	resource	NOUN
fnp-3766	1	292	and	and	CCONJ
fnp-3766	1	293	electronic	electronic	ADJ
fnp-3766	1	294	supplementary	supplementary	ADJ
fnp-3766	1	295	material	material	NOUN
fnp-3766	1	296	:	:	PUNCT
fnp-3766	1	297	supplementary	supplementary	ADJ
fnp-3766	1	298	material	material	NOUN
fnp-3766	1	299	keywords	keyword	NOUN
fnp-3766	1	300	:	:	PUNCT
fnp-3766	1	301	amyloid	amyloid	NOUN
fnp-3766	1	302	-	-	PUNCT
fnp-3766	1	303	β	β	NOUN
fnp-3766	1	304	,	,	PUNCT
fnp-3766	1	305	tau	tau	PROPN
fnp-3766	1	306	,	,	PUNCT
fnp-3766	1	307	α	α	NOUN
fnp-3766	1	308	-	-	PUNCT
fnp-3766	1	309	synuclein	synuclein	NOUN
fnp-3766	1	310	,	,	PUNCT
fnp-3766	1	311	seeding	seeding	NOUN
fnp-3766	1	312	,	,	PUNCT
fnp-3766	1	313	alzheimer	alzheimer	PROPN
fnp-3766	1	314	’s	’s	PART
fnp-3766	1	315	disease	disease	NOUN
fnp-3766	1	316	,	,	PUNCT
fnp-3766	1	317	lewy	lewy	PROPN
fnp-3766	1	318	body	body	NOUN
fnp-3766	1	319	dementia	dementia	PROPN
fnp-3766	1	320	abstract	abstract	ADJ
fnp-3766	1	321	background	background	NOUN
fnp-3766	1	322	:	:	PUNCT
fnp-3766	1	323	seeding	seeding	NOUN
fnp-3766	1	324	of	of	ADP
fnp-3766	1	325	pathology	pathology	NOUN
fnp-3766	1	326	related	relate	VERB
fnp-3766	1	327	to	to	ADP
fnp-3766	1	328	alzheimer	alzheimer	PROPN
fnp-3766	1	329	’s	’s	PART
fnp-3766	1	330	disease	disease	NOUN
fnp-3766	1	331	(	(	PUNCT
fnp-3766	1	332	ad	ad	NOUN
fnp-3766	1	333	)	)	PUNCT
fnp-3766	1	334	and	and	CCONJ
fnp-3766	1	335	lewy	lewy	PROPN
fnp-3766	1	336	body	body	NOUN
fnp-3766	1	337	disease	disease	NOUN
fnp-3766	1	338	(	(	PUNCT
fnp-3766	1	339	lbd	lbd	PROPN
fnp-3766	1	340	)	)	PUNCT
fnp-3766	1	341	by	by	ADP
fnp-3766	1	342	tissue	tissue	NOUN
fnp-3766	1	343	homogenates	homogenate	NOUN
fnp-3766	1	344	or	or	CCONJ
fnp-3766	1	345	purified	purified	ADJ
fnp-3766	1	346	protein	protein	NOUN
fnp-3766	1	347	aggregates	aggregate	NOUN
fnp-3766	1	348	in	in	ADP
fnp-3766	1	349	various	various	ADJ
fnp-3766	1	350	model	model	NOUN
fnp-3766	1	351	systems	system	NOUN
fnp-3766	1	352	has	have	AUX
fnp-3766	1	353	revealed	reveal	VERB
fnp-3766	1	354	prion	prion	NOUN
fnp-3766	1	355	-	-	PUNCT
fnp-3766	1	356	like	like	ADJ
fnp-3766	1	357	properties	property	NOUN
fnp-3766	1	358	of	of	ADP
fnp-3766	1	359	these	these	DET
fnp-3766	1	360	disorders	disorder	NOUN
fnp-3766	1	361	.	.	PUNCT
fnp-3766	2	1	typically	typically	ADV
fnp-3766	2	2	,	,	PUNCT
fnp-3766	2	3	these	these	DET
fnp-3766	2	4	homogenates	homogenate	NOUN
fnp-3766	2	5	are	be	AUX
fnp-3766	2	6	injected	inject	VERB
fnp-3766	2	7	into	into	ADP
fnp-3766	2	8	adult	adult	NOUN
fnp-3766	2	9	mice	mouse	NOUN
fnp-3766	2	10	stereotaxically	stereotaxically	ADV
fnp-3766	2	11	.	.	PUNCT
fnp-3766	3	1	injection	injection	NOUN
fnp-3766	3	2	of	of	ADP
fnp-3766	3	3	brain	brain	NOUN
fnp-3766	3	4	lysates	lysate	NOUN
fnp-3766	3	5	into	into	ADP
fnp-3766	3	6	newborn	newborn	ADJ
fnp-3766	3	7	mice	mouse	NOUN
fnp-3766	3	8	represents	represent	VERB
fnp-3766	3	9	an	an	DET
fnp-3766	3	10	alternative	alternative	ADJ
fnp-3766	3	11	approach	approach	NOUN
fnp-3766	3	12	of	of	ADP
fnp-3766	3	13	delivering	deliver	VERB
fnp-3766	3	14	seeds	seed	NOUN
fnp-3766	3	15	that	that	PRON
fnp-3766	3	16	could	could	AUX
fnp-3766	3	17	direct	direct	VERB
fnp-3766	3	18	the	the	DET
fnp-3766	3	19	evolution	evolution	NOUN
fnp-3766	3	20	of	of	ADP
fnp-3766	3	21	amyloid	amyloid	NOUN
fnp-3766	3	22	-	-	PUNCT
fnp-3766	3	23	β	β	X
fnp-3766	3	24	(	(	PUNCT
fnp-3766	3	25	aβ	aβ	PROPN
fnp-3766	3	26	)	)	PUNCT
fnp-3766	3	27	pathology	pathology	NOUN
fnp-3766	3	28	co	co	VERB
fnp-3766	3	29	-	-	VERB
fnp-3766	3	30	mixed	mixed	ADJ
fnp-3766	3	31	with	with	ADP
fnp-3766	3	32	either	either	CCONJ
fnp-3766	3	33	tau	tau	PROPN
fnp-3766	3	34	or	or	CCONJ
fnp-3766	3	35	α	α	PROPN
fnp-3766	3	36	-	-	PUNCT
fnp-3766	3	37	synuclein	synuclein	NOUN
fnp-3766	3	38	(	(	PUNCT
fnp-3766	3	39	αsyn	αsyn	PROPN
fnp-3766	3	40	)	)	PUNCT
fnp-3766	3	41	pathology	pathology	NOUN
fnp-3766	3	42	in	in	ADP
fnp-3766	3	43	susceptible	susceptible	ADJ
fnp-3766	3	44	mouse	mouse	NOUN
fnp-3766	3	45	models	model	NOUN
fnp-3766	3	46	.	.	PUNCT
fnp-3766	4	1	methods	method	NOUN
fnp-3766	4	2	:	:	PUNCT
fnp-3766	4	3	homogenates	homogenate	NOUN
fnp-3766	4	4	of	of	ADP
fnp-3766	4	5	human	human	ADJ
fnp-3766	4	6	pre	pre	ADJ
fnp-3766	4	7	-	-	ADJ
fnp-3766	4	8	frontal	frontal	ADJ
fnp-3766	4	9	cortex	cortex	NOUN
fnp-3766	4	10	were	be	AUX
fnp-3766	4	11	injected	inject	VERB
fnp-3766	4	12	into	into	ADP
fnp-3766	4	13	the	the	DET
fnp-3766	4	14	lateral	lateral	ADJ
fnp-3766	4	15	ventricles	ventricle	NOUN
fnp-3766	4	16	of	of	ADP
fnp-3766	4	17	newborn	newborn	ADJ
fnp-3766	4	18	(	(	PUNCT
fnp-3766	4	19	p0	p0	NOUN
fnp-3766	4	20	)	)	PUNCT
fnp-3766	4	21	mice	mouse	NOUN
fnp-3766	4	22	expressing	express	VERB
fnp-3766	4	23	a	a	DET
fnp-3766	4	24	mutant	mutant	ADJ
fnp-3766	4	25	humanized	humanize	VERB
fnp-3766	4	26	amyloid	amyloid	NOUN
fnp-3766	4	27	precursor	precursor	NOUN
fnp-3766	4	28	protein	protein	NOUN
fnp-3766	4	29	(	(	PUNCT
fnp-3766	4	30	app	app	NOUN
fnp-3766	4	31	)	)	PUNCT
fnp-3766	4	32	,	,	PUNCT
fnp-3766	4	33	human	human	PROPN
fnp-3766	4	34	p301l	p301l	PROPN
fnp-3766	4	35	tau	tau	PROPN
fnp-3766	4	36	,	,	PUNCT
fnp-3766	4	37	human	human	ADJ
fnp-3766	4	38	wild	wild	ADJ
fnp-3766	4	39	type	type	NOUN
fnp-3766	4	40	αsyn	αsyn	NOUN
fnp-3766	4	41	,	,	PUNCT
fnp-3766	4	42	or	or	CCONJ
fnp-3766	4	43	combinations	combination	NOUN
fnp-3766	4	44	thereof	thereof	ADV
fnp-3766	4	45	.	.	PUNCT
fnp-3766	5	1	the	the	DET
fnp-3766	5	2	homogenates	homogenate	NOUN
fnp-3766	5	3	were	be	AUX
fnp-3766	5	4	prepared	prepare	VERB
fnp-3766	5	5	from	from	ADP
fnp-3766	5	6	ad	ad	NOUN
fnp-3766	5	7	and	and	CCONJ
fnp-3766	5	8	ad	ad	NOUN
fnp-3766	5	9	/	/	SYM
fnp-3766	5	10	lbd	lbd	PROPN
fnp-3766	5	11	cases	case	NOUN
fnp-3766	5	12	displaying	display	VERB
fnp-3766	5	13	variable	variable	ADJ
fnp-3766	5	14	degrees	degree	NOUN
fnp-3766	5	15	of	of	ADP
fnp-3766	5	16	aβ	aβ	DET
fnp-3766	5	17	pathology	pathology	NOUN
fnp-3766	5	18	and	and	CCONJ
fnp-3766	5	19	co	co	VERB
fnp-3766	5	20	-	-	ADJ
fnp-3766	5	21	existing	exist	VERB
fnp-3766	5	22	tau	tau	NOUN
fnp-3766	5	23	and	and	CCONJ
fnp-3766	5	24	αsyn	αsyn	ADJ
fnp-3766	5	25	deposits	deposit	NOUN
fnp-3766	5	26	.	.	PUNCT
fnp-3766	6	1	behavioral	behavioral	ADJ
fnp-3766	6	2	assessments	assessment	NOUN
fnp-3766	6	3	of	of	ADP
fnp-3766	6	4	app	app	NOUN
fnp-3766	6	5	transgenic	transgenic	NOUN
fnp-3766	6	6	mice	mouse	NOUN
fnp-3766	6	7	injected	inject	VERB
fnp-3766	6	8	with	with	ADP
fnp-3766	6	9	ad	ad	NOUN
fnp-3766	6	10	brain	brain	NOUN
fnp-3766	6	11	lysates	lysate	NOUN
fnp-3766	6	12	were	be	AUX
fnp-3766	6	13	conducted	conduct	VERB
fnp-3766	6	14	.	.	PUNCT
fnp-3766	7	1	for	for	ADP
fnp-3766	7	2	comparison	comparison	NOUN
fnp-3766	7	3	,	,	PUNCT
fnp-3766	7	4	homogenates	homogenate	NOUN
fnp-3766	7	5	of	of	ADP
fnp-3766	7	6	aged	aged	ADJ
fnp-3766	7	7	app	app	NOUN
fnp-3766	7	8	transgenic	transgenic	NOUN
fnp-3766	7	9	mice	mouse	NOUN
fnp-3766	7	10	that	that	PRON
fnp-3766	7	11	preferentially	preferentially	ADV
fnp-3766	7	12	exhibit	exhibit	VERB
fnp-3766	7	13	diffuse	diffuse	NOUN
fnp-3766	7	14	or	or	CCONJ
fnp-3766	7	15	cored	core	VERB
fnp-3766	7	16	deposits	deposit	NOUN
fnp-3766	7	17	were	be	AUX
fnp-3766	7	18	similarly	similarly	ADV
fnp-3766	7	19	injected	inject	VERB
fnp-3766	7	20	into	into	ADP
fnp-3766	7	21	the	the	DET
fnp-3766	7	22	brains	brain	NOUN
fnp-3766	7	23	of	of	ADP
fnp-3766	7	24	newborn	newborn	ADJ
fnp-3766	7	25	app	app	NOUN
fnp-3766	7	26	mice	mouse	NOUN
fnp-3766	7	27	.	.	PUNCT
fnp-3766	8	1	results	result	NOUN
fnp-3766	8	2	:	:	PUNCT
fnp-3766	8	3	we	we	PRON
fnp-3766	8	4	observed	observe	VERB
fnp-3766	8	5	that	that	SCONJ
fnp-3766	8	6	lysates	lysate	NOUN
fnp-3766	8	7	from	from	ADP
fnp-3766	8	8	the	the	DET
fnp-3766	8	9	brains	brain	NOUN
fnp-3766	8	10	with	with	ADP
fnp-3766	8	11	ad	ad	NOUN
fnp-3766	8	12	(	(	PUNCT
fnp-3766	8	13	aβ+	aβ+	NOUN
fnp-3766	8	14	,	,	PUNCT
fnp-3766	8	15	tau+	tau+	PROPN
fnp-3766	8	16	)	)	PUNCT
fnp-3766	8	17	,	,	PUNCT
fnp-3766	8	18	ad	ad	NOUN
fnp-3766	8	19	/	/	SYM
fnp-3766	8	20	lbd	lbd	PROPN
fnp-3766	8	21	(	(	PUNCT
fnp-3766	8	22	aβ+	aβ+	PROPN
fnp-3766	8	23	,	,	PUNCT
fnp-3766	8	24	tau+	tau+	PROPN
fnp-3766	8	25	,	,	PUNCT
fnp-3766	8	26	αsyn+	αsyn+	ADJ
fnp-3766	8	27	)	)	PUNCT
fnp-3766	8	28	,	,	PUNCT
fnp-3766	8	29	or	or	CCONJ
fnp-3766	8	30	pathological	pathological	ADJ
fnp-3766	8	31	aging	aging	NOUN
fnp-3766	8	32	(	(	PUNCT
fnp-3766	8	33	aβ+	aβ+	NOUN
fnp-3766	8	34	,	,	PUNCT
fnp-3766	8	35	tau-	tau-	INTJ
fnp-3766	8	36	,	,	PUNCT
fnp-3766	8	37	αsyn-	αsyn-	NOUN
fnp-3766	8	38	)	)	PUNCT
fnp-3766	8	39	efficiently	efficiently	ADV
fnp-3766	8	40	seeded	seed	VERB
fnp-3766	8	41	diffuse	diffuse	NOUN
fnp-3766	8	42	aβ	aβ	ADP
fnp-3766	8	43	deposits	deposit	NOUN
fnp-3766	8	44	.	.	PUNCT
fnp-3766	9	1	moderate	moderate	ADJ
fnp-3766	9	2	seeding	seeding	NOUN
fnp-3766	9	3	of	of	ADP
fnp-3766	9	4	cerebral	cerebral	ADJ
fnp-3766	9	5	amyloid	amyloid	NOUN
fnp-3766	9	6	angiopathy	angiopathy	ADJ
fnp-3766	9	7	(	(	PUNCT
fnp-3766	9	8	caa	caa	NOUN
fnp-3766	9	9	)	)	PUNCT
fnp-3766	9	10	was	be	AUX
fnp-3766	9	11	also	also	ADV
fnp-3766	9	12	observed	observe	VERB
fnp-3766	9	13	.	.	PUNCT
fnp-3766	10	1	no	no	DET
fnp-3766	10	2	animal	animal	NOUN
fnp-3766	10	3	of	of	ADP
fnp-3766	10	4	any	any	DET
fnp-3766	10	5	genotype	genotype	NOUN
fnp-3766	10	6	developed	develop	VERB
fnp-3766	10	7	discernable	discernable	ADJ
fnp-3766	10	8	tau	tau	NOUN
fnp-3766	10	9	or	or	CCONJ
fnp-3766	10	10	αsyn	αsyn	ADJ
fnp-3766	10	11	pathology	pathology	NOUN
fnp-3766	10	12	.	.	PUNCT
fnp-3766	11	1	performance	performance	NOUN
fnp-3766	11	2	in	in	ADP
fnp-3766	11	3	fear	fear	NOUN
fnp-3766	11	4	-	-	PUNCT
fnp-3766	11	5	conditioning	condition	VERB
fnp-3766	11	6	cognitive	cognitive	ADJ
fnp-3766	11	7	tasks	task	NOUN
fnp-3766	11	8	was	be	AUX
fnp-3766	11	9	not	not	PART
fnp-3766	11	10	significantly	significantly	ADV
fnp-3766	11	11	altered	alter	VERB
fnp-3766	11	12	in	in	ADP
fnp-3766	11	13	app	app	NOUN
fnp-3766	11	14	transgenic	transgenic	NOUN
fnp-3766	11	15	animals	animal	NOUN
fnp-3766	11	16	injected	inject	VERB
fnp-3766	11	17	with	with	ADP
fnp-3766	11	18	ad	ad	NOUN
fnp-3766	11	19	brain	brain	NOUN
fnp-3766	11	20	lysates	lysate	NOUN
fnp-3766	11	21	compared	compare	VERB
fnp-3766	11	22	to	to	ADP
fnp-3766	11	23	nontransgenic	nontransgenic	ADJ
fnp-3766	11	24	controls	control	NOUN
fnp-3766	11	25	.	.	PUNCT
fnp-3766	12	1	homogenates	homogenate	NOUN
fnp-3766	12	2	prepared	prepare	VERB
fnp-3766	12	3	from	from	ADP
fnp-3766	12	4	aged	aged	ADJ
fnp-3766	12	5	app	app	NOUN
fnp-3766	12	6	transgenic	transgenic	NOUN
fnp-3766	12	7	mice	mouse	NOUN
fnp-3766	12	8	with	with	ADP
fnp-3766	12	9	diffuse	diffuse	NOUN
fnp-3766	12	10	aβ	aβ	ADP
fnp-3766	12	11	deposits	deposit	NOUN
fnp-3766	12	12	induced	induce	VERB
fnp-3766	12	13	similar	similar	ADJ
fnp-3766	12	14	deposits	deposit	NOUN
fnp-3766	12	15	in	in	ADP
fnp-3766	12	16	app	app	NOUN
fnp-3766	12	17	host	host	NOUN
fnp-3766	12	18	mice	mouse	NOUN
fnp-3766	12	19	;	;	PUNCT
fnp-3766	12	20	whereas	whereas	SCONJ
fnp-3766	12	21	homogenates	homogenate	NOUN
fnp-3766	12	22	from	from	ADP
fnp-3766	12	23	app	app	NOUN
fnp-3766	12	24	mice	mouse	NOUN
fnp-3766	12	25	with	with	ADP
fnp-3766	12	26	cored	core	VERB
fnp-3766	12	27	deposits	deposit	NOUN
fnp-3766	12	28	induced	induce	VERB
fnp-3766	12	29	similar	similar	ADJ
fnp-3766	12	30	cored	cored	ADJ
fnp-3766	12	31	deposits	deposit	NOUN
fnp-3766	12	32	,	,	PUNCT
fnp-3766	12	33	albeit	albeit	SCONJ
fnp-3766	12	34	at	at	ADP
fnp-3766	12	35	a	a	DET
fnp-3766	12	36	lower	low	ADJ
fnp-3766	12	37	level	level	NOUN
fnp-3766	12	38	.	.	PUNCT
fnp-3766	13	1	conclusions	conclusion	NOUN
fnp-3766	13	2	:	:	PUNCT
fnp-3766	13	3	these	these	DET
fnp-3766	13	4	findings	finding	NOUN
fnp-3766	13	5	are	be	AUX
fnp-3766	13	6	consistent	consistent	ADJ
fnp-3766	13	7	with	with	ADP
fnp-3766	13	8	the	the	DET
fnp-3766	13	9	idea	idea	NOUN
fnp-3766	13	10	that	that	PRON
fnp-3766	13	11	diffuse	diffuse	VERB
fnp-3766	13	12	aβ	aβ	PRON
fnp-3766	13	13	pathology	pathology	NOUN
fnp-3766	13	14	,	,	PUNCT
fnp-3766	13	15	which	which	PRON
fnp-3766	13	16	is	be	AUX
fnp-3766	13	17	a	a	DET
fnp-3766	13	18	common	common	ADJ
fnp-3766	13	19	feature	feature	NOUN
fnp-3766	13	20	of	of	ADP
fnp-3766	13	21	human	human	ADJ
fnp-3766	13	22	ad	ad	NOUN
fnp-3766	13	23	,	,	PUNCT
fnp-3766	13	24	ad	ad	NOUN
fnp-3766	13	25	/	/	SYM
fnp-3766	13	26	lbd	lbd	PROPN
fnp-3766	13	27	,	,	PUNCT
fnp-3766	13	28	and	and	CCONJ
fnp-3766	13	29	pa	pa	PROPN
fnp-3766	13	30	brains	brain	NOUN
fnp-3766	13	31	,	,	PUNCT
fnp-3766	13	32	may	may	AUX
fnp-3766	13	33	arise	arise	VERB
fnp-3766	13	34	from	from	ADP
fnp-3766	13	35	a	a	DET
fnp-3766	13	36	distinct	distinct	ADJ
fnp-3766	13	37	strain	strain	NOUN
fnp-3766	13	38	of	of	ADP
fnp-3766	13	39	misfolded	misfolde	VERB
fnp-3766	13	40	aβ	aβ	PRON
fnp-3766	13	41	that	that	PRON
fnp-3766	13	42	is	be	AUX
fnp-3766	13	43	highly	highly	ADV
fnp-3766	13	44	transmissible	transmissible	ADJ
fnp-3766	13	45	to	to	ADP
fnp-3766	13	46	newborn	newborn	ADJ
fnp-3766	13	47	transgenic	transgenic	NOUN
fnp-3766	13	48	app	app	NOUN
fnp-3766	13	49	mice	mouse	NOUN
fnp-3766	13	50	.	.	PUNCT
fnp-3766	14	1	seeding	seed	VERB
fnp-3766	14	2	of	of	ADP
fnp-3766	14	3	tau	tau	PROPN
fnp-3766	14	4	or	or	CCONJ
fnp-3766	14	5	αsyn	αsyn	NOUN
fnp-3766	14	6	comorbidities	comorbiditie	NOUN
fnp-3766	14	7	was	be	AUX
fnp-3766	14	8	inefficient	inefficient	ADJ
fnp-3766	14	9	in	in	ADP
fnp-3766	14	10	the	the	DET
fnp-3766	14	11	models	model	NOUN
fnp-3766	14	12	we	we	PRON
fnp-3766	14	13	used	use	VERB
fnp-3766	14	14	,	,	PUNCT
fnp-3766	14	15	indicating	indicate	VERB
fnp-3766	14	16	that	that	SCONJ
fnp-3766	14	17	additional	additional	ADJ
fnp-3766	14	18	methodological	methodological	ADJ
fnp-3766	14	19	refinement	refinement	NOUN
fnp-3766	14	20	will	will	AUX
fnp-3766	14	21	be	be	AUX
fnp-3766	14	22	needed	need	VERB
fnp-3766	14	23	to	to	PART
fnp-3766	14	24	efficiently	efficiently	ADV
fnp-3766	14	25	seed	seed	VERB
fnp-3766	14	26	ad	ad	NOUN
fnp-3766	14	27	or	or	CCONJ
fnp-3766	14	28	ad	ad	NOUN
fnp-3766	14	29	/	/	SYM
fnp-3766	14	30	lbd	lbd	PROPN
fnp-3766	14	31	mixed	mixed	ADJ
fnp-3766	14	32	pathologies	pathology	NOUN
fnp-3766	14	33	by	by	ADP
fnp-3766	14	34	injecting	inject	VERB
fnp-3766	14	35	newborn	newborn	ADJ
fnp-3766	14	36	mice	mouse	NOUN
fnp-3766	14	37	.	.	PUNCT
fnp-3766	15	1	abbreviations	abbreviation	NOUN
fnp-3766	15	2	ad	ad	PROPN
fnp-3766	15	3	alzheimer	alzheimer	PROPN
fnp-3766	15	4	’s	’s	PART
fnp-3766	15	5	disease	disease	NOUN
fnp-3766	15	6	,	,	PUNCT
fnp-3766	15	7	lbd	lbd	PROPN
fnp-3766	15	8	lewy	lewy	PROPN
fnp-3766	15	9	body	body	PROPN
fnp-3766	15	10	disease	disease	NOUN
fnp-3766	15	11	,	,	PUNCT
fnp-3766	15	12	ad	ad	NOUN
fnp-3766	15	13	/	/	SYM
fnp-3766	15	14	lbd	lbd	PROPN
fnp-3766	15	15	alzheimer	alzheimer	PROPN
fnp-3766	15	16	’s	’s	PART
fnp-3766	15	17	disease	disease	PROPN
fnp-3766	15	18	/	/	SYM
fnp-3766	15	19	lewy	lewy	PROPN
fnp-3766	15	20	body	body	NOUN
fnp-3766	15	21	disease	disease	NOUN
fnp-3766	15	22	,	,	PUNCT
fnp-3766	15	23	aβ	aβ	DET
fnp-3766	15	24	amyloid	amyloid	NOUN
fnp-3766	15	25	-	-	PUNCT
fnp-3766	15	26	β	β	NOUN
fnp-3766	15	27	,	,	PUNCT
fnp-3766	15	28	αsyn	αsyn	PROPN
fnp-3766	15	29	α	α	PROPN
fnp-3766	15	30	-	-	PUNCT
fnp-3766	15	31	synuclein	synuclein	NOUN
fnp-3766	15	32	,	,	PUNCT
fnp-3766	15	33	app	app	PROPN
fnp-3766	15	34	amyloid	amyloid	NOUN
fnp-3766	15	35	precursor	precursor	NOUN
fnp-3766	15	36	protein	protein	NOUN
fnp-3766	15	37	,	,	PUNCT
fnp-3766	15	38	pa	pa	PROPN
fnp-3766	15	39	pathological	pathological	ADJ
fnp-3766	15	40	aging	aging	NOUN
fnp-3766	15	41	,	,	PUNCT
fnp-3766	15	42	gfap	gfap	ADJ
fnp-3766	15	43	glial	glial	ADJ
fnp-3766	15	44	fibrillary	fibrillary	ADJ
fnp-3766	15	45	acidic	acidic	ADJ
fnp-3766	15	46	protein	protein	NOUN
fnp-3766	15	47	,	,	PUNCT
fnp-3766	15	48	mapt	mapt	VERB
fnp-3766	15	49	microtubule	microtubule	NOUN
fnp-3766	15	50	-	-	PUNCT
fnp-3766	15	51	associated	associate	VERB
fnp-3766	15	52	protein	protein	NOUN
fnp-3766	15	53	tau	tau	PROPN
fnp-3766	15	54	,	,	PUNCT
fnp-3766	15	55	ndc	ndc	PROPN
fnp-3766	15	56	nondemented	nondemente	VERB
fnp-3766	15	57	controls	control	NOUN
fnp-3766	15	58	,	,	PUNCT
fnp-3766	15	59	wt	wt	ADP
fnp-3766	15	60	wild	wild	ADJ
fnp-3766	15	61	type	type	NOUN
fnp-3766	15	62	,	,	PUNCT
fnp-3766	15	63	caa	caa	NOUN
fnp-3766	15	64	cerebral	cerebral	ADJ
fnp-3766	15	65	amyloid	amyloid	PROPN
fnp-3766	15	66	angiopathy	angiopathy	NOUN
fnp-3766	15	67	,	,	PUNCT
fnp-3766	15	68	elisa	elisa	VERB
fnp-3766	15	69	enzyme	enzyme	NOUN
fnp-3766	15	70	linked	link	VERB
fnp-3766	15	71	immunosorbent	immunosorbent	ADJ
fnp-3766	15	72	assay	assay	PROPN
fnp-3766	15	73	,	,	PUNCT
fnp-3766	15	74	sds	sds	PROPN
fnp-3766	15	75	sodium	sodium	PROPN
fnp-3766	15	76	dodecyl	dodecyl	PROPN
fnp-3766	15	77	sulfate	sulfate	NOUN
fnp-3766	15	78	,	,	PUNCT
fnp-3766	15	79	fa	fa	PROPN
fnp-3766	15	80	formic	formic	PROPN
fnp-3766	15	81	acid	acid	PROPN
fnp-3766	15	82	,	,	PUNCT
fnp-3766	15	83	thio	thio	NOUN
fnp-3766	15	84	-	-	PUNCT
fnp-3766	15	85	s	s	NOUN
fnp-3766	15	86	thioflavin	thioflavin	PROPN
fnp-3766	15	87	s.	s.	PROPN
fnp-3766	15	88	background	background	PROPN
fnp-3766	15	89	the	the	DET
fnp-3766	15	90	amyloid	amyloid	NOUN
fnp-3766	15	91	cascade	cascade	NOUN
fnp-3766	15	92	hypothesis	hypothesis	NOUN
fnp-3766	15	93	posits	posit	NOUN
fnp-3766	15	94	that	that	PRON
fnp-3766	15	95	deposition	deposition	NOUN
fnp-3766	15	96	of	of	ADP
fnp-3766	15	97	the	the	DET
fnp-3766	15	98	aβ	aβ	NOUN
fnp-3766	15	99	peptide	peptide	NOUN
fnp-3766	15	100	is	be	AUX
fnp-3766	15	101	an	an	DET
fnp-3766	15	102	initiating	initiate	VERB
fnp-3766	15	103	factor	factor	NOUN
fnp-3766	15	104	in	in	ADP
fnp-3766	15	105	alzheimer	alzheimer	PROPN
fnp-3766	15	106	’s	’s	PART
fnp-3766	15	107	disease	disease	NOUN
fnp-3766	15	108	(	(	PUNCT
fnp-3766	15	109	ad	ad	NOUN
fnp-3766	15	110	)	)	PUNCT
fnp-3766	15	111	with	with	ADP
fnp-3766	15	112	downstream	downstream	ADJ
fnp-3766	15	113	effects	effect	NOUN
fnp-3766	15	114	of	of	ADP
fnp-3766	15	115	increased	increase	VERB
fnp-3766	15	116	inflammatory	inflammatory	ADJ
fnp-3766	15	117	response	response	NOUN
fnp-3766	15	118	,	,	PUNCT
fnp-3766	15	119	altered	alter	VERB
fnp-3766	15	120	neuronal	neuronal	ADJ
fnp-3766	15	121	homeostasis	homeostasis	NOUN
fnp-3766	15	122	,	,	PUNCT
fnp-3766	15	123	altered	alter	VERB
fnp-3766	15	124	tau	tau	PROPN
fnp-3766	15	125	phosphorylation	phosphorylation	NOUN
fnp-3766	15	126	leading	lead	VERB
fnp-3766	15	127	to	to	PART
fnp-3766	15	128	tangle	tangle	VERB
fnp-3766	15	129	formation	formation	NOUN
fnp-3766	15	130	,	,	PUNCT
fnp-3766	15	131	neuronal	neuronal	ADJ
fnp-3766	15	132	dysfunction	dysfunction	NOUN
fnp-3766	15	133	,	,	PUNCT
fnp-3766	15	134	and	and	CCONJ
fnp-3766	15	135	cognitive	cognitive	ADJ
fnp-3766	15	136	decline	decline	NOUN
fnp-3766	15	137	(	(	PUNCT
fnp-3766	15	138	1	1	NUM
fnp-3766	15	139	,	,	PUNCT
fnp-3766	15	140	2	2	NUM
fnp-3766	15	141	)	)	PUNCT
fnp-3766	15	142	.	.	PUNCT
fnp-3766	16	1	the	the	DET
fnp-3766	16	2	interaction	interaction	NOUN
fnp-3766	16	3	between	between	ADP
fnp-3766	16	4	aβ	aβ	ADP
fnp-3766	16	5	and	and	CCONJ
fnp-3766	16	6	tau	tau	PROPN
fnp-3766	16	7	pathology	pathology	NOUN
fnp-3766	16	8	has	have	AUX
fnp-3766	16	9	been	be	AUX
fnp-3766	16	10	modeled	model	VERB
fnp-3766	16	11	in	in	ADP
fnp-3766	16	12	transgenic	transgenic	NOUN
fnp-3766	16	13	animals	animal	NOUN
fnp-3766	16	14	that	that	SCONJ
fnp-3766	16	15	co	co	VERB
fnp-3766	16	16	-	-	ADJ
fnp-3766	16	17	express	express	ADJ
fnp-3766	16	18	human	human	ADJ
fnp-3766	16	19	amyloid	amyloid	NOUN
fnp-3766	16	20	precursor	precursor	NOUN
fnp-3766	16	21	proteins	protein	NOUN
fnp-3766	16	22	(	(	PUNCT
fnp-3766	16	23	app	app	NOUN
fnp-3766	16	24	)	)	PUNCT
fnp-3766	16	25	with	with	ADP
fnp-3766	16	26	mutations	mutation	NOUN
fnp-3766	16	27	associated	associate	VERB
fnp-3766	16	28	with	with	ADP
fnp-3766	16	29	familial	familial	ADJ
fnp-3766	16	30	ad	ad	NOUN
fnp-3766	16	31	(	(	PUNCT
fnp-3766	16	32	fad	fad	NOUN
fnp-3766	16	33	)	)	PUNCT
fnp-3766	16	34	and	and	CCONJ
fnp-3766	16	35	wild	wild	ADJ
fnp-3766	16	36	-	-	PUNCT
fnp-3766	16	37	type	type	NOUN
fnp-3766	16	38	or	or	CCONJ
fnp-3766	16	39	mutant	mutant	ADJ
fnp-3766	16	40	human	human	ADJ
fnp-3766	16	41	tau	tau	PROPN
fnp-3766	16	42	(	(	PUNCT
fnp-3766	16	43	3	3	NUM
fnp-3766	16	44	-	-	SYM
fnp-3766	16	45	12	12	NUM
fnp-3766	16	46	)	)	PUNCT
fnp-3766	16	47	.	.	PUNCT
fnp-3766	17	1	multiple	multiple	ADJ
fnp-3766	17	2	studies	study	NOUN
fnp-3766	17	3	report	report	VERB
fnp-3766	17	4	that	that	SCONJ
fnp-3766	17	5	the	the	DET
fnp-3766	17	6	presence	presence	NOUN
fnp-3766	17	7	of	of	ADP
fnp-3766	17	8	aβ	aβ	DET
fnp-3766	17	9	pathology	pathology	NOUN
fnp-3766	17	10	exacerbates	exacerbate	VERB
fnp-3766	17	11	the	the	DET
fnp-3766	17	12	severity	severity	NOUN
fnp-3766	17	13	of	of	ADP
fnp-3766	17	14	tau	tau	PROPN
fnp-3766	17	15	pathology	pathology	NOUN
fnp-3766	17	16	,	,	PUNCT
fnp-3766	17	17	leading	lead	VERB
fnp-3766	17	18	to	to	ADP
fnp-3766	17	19	increased	increase	VERB
fnp-3766	17	20	tau	tau	PROPN
fnp-3766	17	21	phosphorylation	phosphorylation	NOUN
fnp-3766	17	22	or	or	CCONJ
fnp-3766	17	23	increased	increase	VERB
fnp-3766	17	24	levels	level	NOUN
fnp-3766	17	25	of	of	ADP
fnp-3766	17	26	neurofibrillary	neurofibrillary	ADJ
fnp-3766	17	27	tangles	tangle	NOUN
fnp-3766	17	28	(	(	PUNCT
fnp-3766	17	29	3	3	NUM
fnp-3766	17	30	,	,	PUNCT
fnp-3766	17	31	6	6	NUM
fnp-3766	17	32	,	,	PUNCT
fnp-3766	17	33	8	8	NUM
fnp-3766	17	34	,	,	PUNCT
fnp-3766	17	35	10	10	NUM
fnp-3766	17	36	,	,	PUNCT
fnp-3766	17	37	11	11	NUM
fnp-3766	17	38	)	)	PUNCT
fnp-3766	17	39	.	.	PUNCT
fnp-3766	18	1	interactions	interaction	NOUN
fnp-3766	18	2	between	between	ADP
fnp-3766	18	3	aβ	aβ	ADP
fnp-3766	18	4	and	and	CCONJ
fnp-3766	18	5	tau	tau	PROPN
fnp-3766	18	6	pathology	pathology	NOUN
fnp-3766	18	7	have	have	AUX
fnp-3766	18	8	also	also	ADV
fnp-3766	18	9	been	be	AUX
fnp-3766	18	10	modeled	model	VERB
fnp-3766	18	11	in	in	ADP
fnp-3766	18	12	mice	mouse	NOUN
fnp-3766	18	13	by	by	ADP
fnp-3766	18	14	utilizing	utilize	VERB
fnp-3766	18	15	the	the	DET
fnp-3766	18	16	prion	prion	NOUN
fnp-3766	18	17	-	-	PUNCT
fnp-3766	18	18	like	like	ADJ
fnp-3766	18	19	capacity	capacity	NOUN
fnp-3766	18	20	of	of	ADP
fnp-3766	18	21	aβ	aβ	PRON
fnp-3766	18	22	and	and	CCONJ
fnp-3766	18	23	tau	tau	PROPN
fnp-3766	18	24	aggregates	aggregate	VERB
fnp-3766	18	25	to	to	PART
fnp-3766	18	26	seed	seed	NOUN
fnp-3766	18	27	accelerated	accelerate	VERB
fnp-3766	18	28	ad	ad	NOUN
fnp-3766	18	29	pathology	pathology	NOUN
fnp-3766	18	30	.	.	PUNCT
fnp-3766	19	1	aβ	aβ	PRON
fnp-3766	19	2	containing	contain	VERB
fnp-3766	19	3	seeds	seed	NOUN
fnp-3766	19	4	,	,	PUNCT
fnp-3766	19	5	derived	derive	VERB
fnp-3766	19	6	from	from	ADP
fnp-3766	19	7	human	human	ADJ
fnp-3766	19	8	ad	ad	NOUN
fnp-3766	19	9	and	and	CCONJ
fnp-3766	19	10	pathological	pathological	ADJ
fnp-3766	19	11	aging	aging	NOUN
fnp-3766	19	12	(	(	PUNCT
fnp-3766	19	13	pa	pa	NOUN
fnp-3766	19	14	)	)	PUNCT
fnp-3766	19	15	brain	brain	NOUN
fnp-3766	19	16	lysates	lysate	NOUN
fnp-3766	19	17	,	,	PUNCT
fnp-3766	19	18	have	have	AUX
fnp-3766	19	19	been	be	AUX
fnp-3766	19	20	shown	show	VERB
fnp-3766	19	21	to	to	PART
fnp-3766	19	22	accelerate	accelerate	VERB
fnp-3766	19	23	the	the	DET
fnp-3766	19	24	time	time	NOUN
fnp-3766	19	25	-	-	PUNCT
fnp-3766	19	26	course	course	NOUN
fnp-3766	19	27	and	and	CCONJ
fnp-3766	19	28	severity	severity	NOUN
fnp-3766	19	29	of	of	ADP
fnp-3766	19	30	aβ	aβ	NOUN
fnp-3766	19	31	deposition	deposition	NOUN
fnp-3766	19	32	in	in	ADP
fnp-3766	19	33	amyloid	amyloid	NOUN
fnp-3766	19	34	precursor	precursor	NOUN
fnp-3766	19	35	protein	protein	NOUN
fnp-3766	19	36	(	(	PUNCT
fnp-3766	19	37	app	app	NOUN
fnp-3766	19	38	)	)	PUNCT
fnp-3766	19	39	transgenic	transgenic	NOUN
fnp-3766	19	40	models	model	NOUN
fnp-3766	19	41	as	as	ADV
fnp-3766	19	42	well	well	ADV
fnp-3766	19	43	as	as	ADP
fnp-3766	19	44	impact	impact	VERB
fnp-3766	19	45	the	the	DET
fnp-3766	19	46	morphology	morphology	NOUN
fnp-3766	19	47	of	of	ADP
fnp-3766	19	48	the	the	DET
fnp-3766	19	49	seeded	seeded	ADJ
fnp-3766	19	50	deposits	deposit	NOUN
fnp-3766	19	51	(	(	PUNCT
fnp-3766	19	52	for	for	ADP
fnp-3766	19	53	review	review	NOUN
fnp-3766	19	54	see	see	VERB
fnp-3766	19	55	(	(	PUNCT
fnp-3766	19	56	13	13	NUM
fnp-3766	19	57	)	)	PUNCT
fnp-3766	19	58	)	)	PUNCT
fnp-3766	19	59	.	.	PUNCT
fnp-3766	20	1	seeding	seed	VERB
fnp-3766	20	2	preparations	preparation	NOUN
fnp-3766	20	3	can	can	AUX
fnp-3766	20	4	consist	consist	VERB
fnp-3766	20	5	of	of	ADP
fnp-3766	20	6	human	human	ADJ
fnp-3766	20	7	brain	brain	NOUN
fnp-3766	20	8	homogenates	homogenate	NOUN
fnp-3766	20	9	,	,	PUNCT
fnp-3766	20	10	app	app	X
fnp-3766	20	11	transgenic	transgenic	NOUN
fnp-3766	20	12	mouse	mouse	NOUN
fnp-3766	20	13	brain	brain	NOUN
fnp-3766	20	14	homogenates	homogenate	NOUN
fnp-3766	20	15	,	,	PUNCT
fnp-3766	20	16	enriched	enrich	VERB
fnp-3766	20	17	preparations	preparation	NOUN
fnp-3766	20	18	derived	derive	VERB
fnp-3766	20	19	from	from	ADP
fnp-3766	20	20	such	such	ADJ
fnp-3766	20	21	homogenates	homogenate	NOUN
fnp-3766	20	22	and	and	CCONJ
fnp-3766	20	23	synthetic	synthetic	ADJ
fnp-3766	20	24	aβ	aβ	NOUN
fnp-3766	20	25	fibrils	fibril	NOUN
fnp-3766	20	26	(	(	PUNCT
fnp-3766	20	27	13	13	NUM
fnp-3766	20	28	)	)	PUNCT
fnp-3766	20	29	.	.	PUNCT
fnp-3766	21	1	in	in	ADP
fnp-3766	21	2	most	most	ADJ
fnp-3766	21	3	of	of	ADP
fnp-3766	21	4	these	these	DET
fnp-3766	21	5	published	publish	VERB
fnp-3766	21	6	studies	study	NOUN
fnp-3766	21	7	,	,	PUNCT
fnp-3766	21	8	seeds	seed	NOUN
fnp-3766	21	9	are	be	AUX
fnp-3766	21	10	injected	inject	VERB
fnp-3766	21	11	into	into	ADP
fnp-3766	21	12	adult	adult	NOUN
fnp-3766	21	13	app	app	NOUN
fnp-3766	21	14	mice	mouse	NOUN
fnp-3766	21	15	that	that	PRON
fnp-3766	21	16	are	be	AUX
fnp-3766	21	17	a	a	DET
fnp-3766	21	18	few	few	ADJ
fnp-3766	21	19	months	month	NOUN
fnp-3766	21	20	away	away	ADV
fnp-3766	21	21	from	from	ADP
fnp-3766	21	22	developing	develop	VERB
fnp-3766	21	23	aβ	aβ	PRON
fnp-3766	21	24	pathology	pathology	NOUN
fnp-3766	21	25	on	on	ADP
fnp-3766	21	26	their	their	PRON
fnp-3766	21	27	own	own	ADJ
fnp-3766	21	28	and	and	CCONJ
fnp-3766	21	29	in	in	ADP
fnp-3766	21	30	such	such	ADJ
fnp-3766	21	31	cases	case	NOUN
fnp-3766	21	32	the	the	DET
fnp-3766	21	33	inherent	inherent	ADJ
fnp-3766	21	34	pathological	pathological	ADJ
fnp-3766	21	35	tendencies	tendency	NOUN
fnp-3766	21	36	of	of	ADP
fnp-3766	21	37	the	the	DET
fnp-3766	21	38	app	app	NOUN
fnp-3766	21	39	host	host	NOUN
fnp-3766	21	40	model	model	NOUN
fnp-3766	21	41	can	can	AUX
fnp-3766	21	42	contribute	contribute	VERB
fnp-3766	21	43	to	to	ADP
fnp-3766	21	44	the	the	DET
fnp-3766	21	45	pathological	pathological	ADJ
fnp-3766	21	46	outcome	outcome	NOUN
fnp-3766	21	47	.	.	PUNCT
fnp-3766	22	1	partially	partially	ADV
fnp-3766	22	2	purified	purify	VERB
fnp-3766	22	3	tau	tau	PROPN
fnp-3766	22	4	aggregates	aggregate	NOUN
fnp-3766	22	5	from	from	ADP
fnp-3766	22	6	ad	ad	NOUN
fnp-3766	22	7	brains	brain	NOUN
fnp-3766	22	8	were	be	AUX
fnp-3766	22	9	found	find	VERB
fnp-3766	22	10	to	to	PART
fnp-3766	22	11	seed	seed	VERB
fnp-3766	22	12	enhanced	enhance	VERB
fnp-3766	22	13	neuritic	neuritic	ADJ
fnp-3766	22	14	tau	tau	PROPN
fnp-3766	22	15	pathology	pathology	NOUN
fnp-3766	22	16	in	in	ADP
fnp-3766	22	17	the	the	DET
fnp-3766	22	18	5xfad	5xfad	NUM
fnp-3766	22	19	mouse	mouse	NOUN
fnp-3766	22	20	model	model	NOUN
fnp-3766	22	21	and	and	CCONJ
fnp-3766	22	22	the	the	DET
fnp-3766	22	23	appnl	appnl	NOUN
fnp-3766	22	24	-	-	PUNCT
fnp-3766	22	25	g	g	NOUN
fnp-3766	22	26	-	-	PUNCT
fnp-3766	22	27	f	f	NOUN
fnp-3766	22	28	/	/	SYM
fnp-3766	22	29	human	human	ADJ
fnp-3766	22	30	mapt	mapt	NOUN
fnp-3766	22	31	double	double	ADJ
fnp-3766	22	32	knock	knock	NOUN
fnp-3766	22	33	-	-	PUNCT
fnp-3766	22	34	in	in	ADP
fnp-3766	22	35	model	model	NOUN
fnp-3766	22	36	(	(	PUNCT
fnp-3766	22	37	14	14	NUM
fnp-3766	22	38	)	)	PUNCT
fnp-3766	22	39	;	;	PUNCT
fnp-3766	22	40	however	however	ADV
fnp-3766	22	41	,	,	PUNCT
fnp-3766	22	42	neither	neither	PRON
fnp-3766	22	43	of	of	ADP
fnp-3766	22	44	these	these	DET
fnp-3766	22	45	models	model	NOUN
fnp-3766	22	46	produced	produce	VERB
fnp-3766	22	47	pathology	pathology	NOUN
fnp-3766	22	48	resembling	resemble	VERB
fnp-3766	22	49	neurofibrillary	neurofibrillary	ADJ
fnp-3766	22	50	tangles	tangle	NOUN
fnp-3766	22	51	.	.	PUNCT
fnp-3766	23	1	in	in	ADP
fnp-3766	23	2	appswe	appswe	NOUN
fnp-3766	23	3	/	/	SYM
fnp-3766	23	4	ps1de9	ps1de9	PROPN
fnp-3766	23	5	and	and	CCONJ
fnp-3766	23	6	appnl	appnl	NOUN
fnp-3766	23	7	-	-	PUNCT
fnp-3766	23	8	f	f	PROPN
fnp-3766	23	9	/	/	SYM
fnp-3766	23	10	nl	nl	PROPN
fnp-3766	23	11	-	-	PUNCT
fnp-3766	23	12	f	f	PROPN
fnp-3766	23	13	mice	mouse	NOUN
fnp-3766	23	14	crossed	cross	VERB
fnp-3766	23	15	to	to	PART
fnp-3766	23	16	humanized	humanize	VERB
fnp-3766	23	17	htau	htau	ADJ
fnp-3766	23	18	mice	mouse	NOUN
fnp-3766	23	19	,	,	PUNCT
fnp-3766	23	20	the	the	DET
fnp-3766	23	21	presence	presence	NOUN
fnp-3766	23	22	of	of	ADP
fnp-3766	23	23	aβ	aβ	DET
fnp-3766	23	24	pathology	pathology	NOUN
fnp-3766	23	25	did	do	AUX
fnp-3766	23	26	not	not	PART
fnp-3766	23	27	produce	produce	VERB
fnp-3766	23	28	significant	significant	ADJ
fnp-3766	23	29	enhancement	enhancement	NOUN
fnp-3766	23	30	of	of	ADP
fnp-3766	23	31	tau	tau	PROPN
fnp-3766	23	32	seeding	seed	VERB
fnp-3766	23	33	(	(	PUNCT
fnp-3766	23	34	15	15	NUM
fnp-3766	23	35	)	)	PUNCT
fnp-3766	23	36	.	.	PUNCT
fnp-3766	24	1	these	these	DET
fnp-3766	24	2	latter	latter	ADJ
fnp-3766	24	3	studies	study	NOUN
fnp-3766	24	4	illustrate	illustrate	VERB
fnp-3766	24	5	the	the	DET
fnp-3766	24	6	need	need	NOUN
fnp-3766	24	7	to	to	PART
fnp-3766	24	8	refine	refine	VERB
fnp-3766	24	9	seeding	seed	VERB
fnp-3766	24	10	approaches	approach	NOUN
fnp-3766	24	11	towards	towards	ADP
fnp-3766	24	12	producing	produce	VERB
fnp-3766	24	13	models	model	NOUN
fnp-3766	24	14	that	that	PRON
fnp-3766	24	15	reproduce	reproduce	VERB
fnp-3766	24	16	a	a	DET
fnp-3766	24	17	broader	broad	ADJ
fnp-3766	24	18	spectrum	spectrum	NOUN
fnp-3766	24	19	of	of	ADP
fnp-3766	24	20	ad	ad	NOUN
fnp-3766	24	21	-	-	PUNCT
fnp-3766	24	22	related	relate	VERB
fnp-3766	24	23	pathology	pathology	NOUN
fnp-3766	24	24	.	.	PUNCT
fnp-3766	25	1	recent	recent	ADJ
fnp-3766	25	2	studies	study	NOUN
fnp-3766	25	3	have	have	AUX
fnp-3766	25	4	begun	begin	VERB
fnp-3766	25	5	to	to	PART
fnp-3766	25	6	use	use	VERB
fnp-3766	25	7	seeding	seed	VERB
fnp-3766	25	8	approaches	approach	NOUN
fnp-3766	25	9	to	to	PART
fnp-3766	25	10	create	create	VERB
fnp-3766	25	11	models	model	NOUN
fnp-3766	25	12	of	of	ADP
fnp-3766	25	13	mixed	mixed	ADJ
fnp-3766	25	14	ad	ad	NOUN
fnp-3766	25	15	or	or	CCONJ
fnp-3766	25	16	lewy	lewy	ADJ
fnp-3766	25	17	body	body	NOUN
fnp-3766	25	18	disease	disease	NOUN
fnp-3766	25	19	(	(	PUNCT
fnp-3766	25	20	lbd	lbd	PROPN
fnp-3766	25	21	)	)	PUNCT
fnp-3766	25	22	pathology	pathology	NOUN
fnp-3766	25	23	.	.	PUNCT
fnp-3766	26	1	in	in	ADP
fnp-3766	26	2	parkinson	parkinson	NOUN
fnp-3766	26	3	’s	’s	PART
fnp-3766	26	4	disease	disease	NOUN
fnp-3766	26	5	and	and	CCONJ
fnp-3766	26	6	lbd	lbd	PROPN
fnp-3766	26	7	,	,	PUNCT
fnp-3766	26	8	the	the	DET
fnp-3766	26	9	presence	presence	NOUN
fnp-3766	26	10	of	of	ADP
fnp-3766	26	11	aβ	aβ	DET
fnp-3766	26	12	plaques	plaque	NOUN
fnp-3766	26	13	is	be	AUX
fnp-3766	26	14	associated	associate	VERB
fnp-3766	26	15	with	with	ADP
fnp-3766	26	16	cortical	cortical	ADJ
fnp-3766	26	17	αsyn	αsyn	ADJ
fnp-3766	26	18	pathology	pathology	NOUN
fnp-3766	26	19	(	(	PUNCT
fnp-3766	26	20	16	16	NUM
fnp-3766	26	21	,	,	PUNCT
fnp-3766	26	22	17	17	NUM
fnp-3766	26	23	)	)	PUNCT
fnp-3766	26	24	.	.	PUNCT
fnp-3766	27	1	similar	similar	ADJ
fnp-3766	27	2	to	to	ADP
fnp-3766	27	3	studies	study	NOUN
fnp-3766	27	4	of	of	ADP
fnp-3766	27	5	aβ	aβ	PROPN
fnp-3766	27	6	/	/	SYM
fnp-3766	27	7	tau	tau	NOUN
fnp-3766	27	8	interactions	interaction	NOUN
fnp-3766	27	9	,	,	PUNCT
fnp-3766	27	10	investigations	investigation	NOUN
fnp-3766	27	11	of	of	ADP
fnp-3766	27	12	aβ	aβ	NOUN
fnp-3766	27	13	and	and	CCONJ
fnp-3766	27	14	αsyn	αsyn	ADJ
fnp-3766	27	15	interaction	interaction	NOUN
fnp-3766	27	16	in	in	ADP
fnp-3766	27	17	transgenic	transgenic	NOUN
fnp-3766	27	18	mice	mouse	NOUN
fnp-3766	27	19	have	have	AUX
fnp-3766	27	20	suggested	suggest	VERB
fnp-3766	27	21	a	a	DET
fnp-3766	27	22	possible	possible	ADJ
fnp-3766	27	23	synergistic	synergistic	ADJ
fnp-3766	27	24	relationship	relationship	NOUN
fnp-3766	27	25	(	(	PUNCT
fnp-3766	27	26	18	18	NUM
fnp-3766	27	27	,	,	PUNCT
fnp-3766	27	28	19	19	NUM
fnp-3766	27	29	)	)	PUNCT
fnp-3766	27	30	.	.	PUNCT
fnp-3766	28	1	in	in	ADP
fnp-3766	28	2	seeding	seeding	NOUN
fnp-3766	28	3	models	model	NOUN
fnp-3766	28	4	involving	involve	VERB
fnp-3766	28	5	the	the	DET
fnp-3766	28	6	injection	injection	NOUN
fnp-3766	28	7	of	of	ADP
fnp-3766	28	8	αsyn	αsyn	ADJ
fnp-3766	28	9	preformed	preformed	ADJ
fnp-3766	28	10	fibrils	fibril	NOUN
fnp-3766	28	11	,	,	PUNCT
fnp-3766	28	12	aβ	aβ	DET
fnp-3766	28	13	deposits	deposit	NOUN
fnp-3766	28	14	accelerated	accelerate	VERB
fnp-3766	28	15	αsyn	αsyn	ADJ
fnp-3766	28	16	pathogenesis	pathogenesis	NOUN
fnp-3766	28	17	and	and	CCONJ
fnp-3766	28	18	spread	spread	VERB
fnp-3766	28	19	throughout	throughout	ADP
fnp-3766	28	20	the	the	DET
fnp-3766	28	21	brain	brain	NOUN
fnp-3766	28	22	of	of	ADP
fnp-3766	28	23	5xfad	5xfad	NUM
fnp-3766	28	24	mice	mouse	NOUN
fnp-3766	28	25	(	(	PUNCT
fnp-3766	28	26	20	20	NUM
fnp-3766	28	27	)	)	PUNCT
fnp-3766	28	28	and	and	CCONJ
fnp-3766	28	29	in	in	ADP
fnp-3766	28	30	bigenic	bigenic	ADJ
fnp-3766	28	31	mice	mouse	NOUN
fnp-3766	28	32	co	co	VERB
fnp-3766	28	33	-	-	AUX
fnp-3766	28	34	expressing	express	VERB
fnp-3766	28	35	appswe	appswe	NOUN
fnp-3766	28	36	/	/	SYM
fnp-3766	28	37	ps1de9	ps1de9	PROPN
fnp-3766	28	38	and	and	CCONJ
fnp-3766	28	39	wt	wt	PROPN
fnp-3766	28	40	αsyn	αsyn	NOUN
fnp-3766	28	41	(	(	PUNCT
fnp-3766	28	42	21	21	NUM
fnp-3766	28	43	)	)	PUNCT
fnp-3766	28	44	.	.	PUNCT
fnp-3766	29	1	one	one	NUM
fnp-3766	29	2	of	of	ADP
fnp-3766	29	3	the	the	DET
fnp-3766	29	4	goals	goal	NOUN
fnp-3766	29	5	of	of	ADP
fnp-3766	29	6	our	our	PRON
fnp-3766	29	7	study	study	NOUN
fnp-3766	29	8	was	be	AUX
fnp-3766	29	9	to	to	PART
fnp-3766	29	10	further	far	ADV
fnp-3766	29	11	explore	explore	VERB
fnp-3766	29	12	the	the	DET
fnp-3766	29	13	potential	potential	NOUN
fnp-3766	29	14	to	to	PART
fnp-3766	29	15	use	use	VERB
fnp-3766	29	16	seeding	seed	VERB
fnp-3766	29	17	as	as	ADP
fnp-3766	29	18	a	a	DET
fnp-3766	29	19	means	means	NOUN
fnp-3766	29	20	to	to	PART
fnp-3766	29	21	generate	generate	VERB
fnp-3766	29	22	novel	novel	ADJ
fnp-3766	29	23	mouse	mouse	NOUN
fnp-3766	29	24	models	model	NOUN
fnp-3766	29	25	of	of	ADP
fnp-3766	29	26	mixed	mixed	ADJ
fnp-3766	29	27	ad	ad	NOUN
fnp-3766	29	28	and	and	CCONJ
fnp-3766	29	29	lbd	lbd	PROPN
fnp-3766	29	30	pathology	pathology	PROPN
fnp-3766	29	31	.	.	PUNCT
fnp-3766	30	1	a	a	DET
fnp-3766	30	2	subset	subset	NOUN
fnp-3766	30	3	of	of	ADP
fnp-3766	30	4	cognitively	cognitively	ADV
fnp-3766	30	5	normal	normal	ADJ
fnp-3766	30	6	aged	aged	ADJ
fnp-3766	30	7	individuals	individual	NOUN
fnp-3766	30	8	exhibit	exhibit	VERB
fnp-3766	30	9	substantial	substantial	ADJ
fnp-3766	30	10	aβ	aβ	NOUN
fnp-3766	30	11	pathology	pathology	NOUN
fnp-3766	30	12	at	at	ADP
fnp-3766	30	13	autopsy	autopsy	ADJ
fnp-3766	30	14	(	(	PUNCT
fnp-3766	30	15	22	22	NUM
fnp-3766	30	16	)	)	PUNCT
fnp-3766	30	17	.	.	PUNCT
fnp-3766	31	1	these	these	DET
fnp-3766	31	2	individuals	individual	NOUN
fnp-3766	31	3	,	,	PUNCT
fnp-3766	31	4	which	which	PRON
fnp-3766	31	5	we	we	PRON
fnp-3766	31	6	use	use	VERB
fnp-3766	31	7	the	the	DET
fnp-3766	31	8	designation	designation	NOUN
fnp-3766	31	9	of	of	ADP
fnp-3766	31	10	pathologic	pathologic	ADJ
fnp-3766	31	11	aging	aging	NOUN
fnp-3766	31	12	(	(	PUNCT
fnp-3766	31	13	pa	pa	PROPN
fnp-3766	31	14	)	)	PUNCT
fnp-3766	31	15	,	,	PUNCT
fnp-3766	31	16	may	may	AUX
fnp-3766	31	17	represent	represent	VERB
fnp-3766	31	18	prodromal	prodromal	ADJ
fnp-3766	31	19	,	,	PUNCT
fnp-3766	31	20	presymptomatic	presymptomatic	ADJ
fnp-3766	31	21	ad	ad	NOUN
fnp-3766	31	22	(	(	PUNCT
fnp-3766	31	23	23	23	NUM
fnp-3766	31	24	-	-	SYM
fnp-3766	31	25	26	26	NUM
fnp-3766	31	26	)	)	PUNCT
fnp-3766	31	27	.	.	PUNCT
fnp-3766	32	1	the	the	DET
fnp-3766	32	2	amyloid	amyloid	NOUN
fnp-3766	32	3	pathology	pathology	NOUN
fnp-3766	32	4	of	of	ADP
fnp-3766	32	5	pa	pa	PROPN
fnp-3766	32	6	brains	brain	NOUN
fnp-3766	32	7	has	have	AUX
fnp-3766	32	8	typically	typically	ADV
fnp-3766	32	9	been	be	AUX
fnp-3766	32	10	described	describe	VERB
fnp-3766	32	11	as	as	ADP
fnp-3766	32	12	diffuse	diffuse	NOUN
fnp-3766	32	13	in	in	ADP
fnp-3766	32	14	nature	nature	NOUN
fnp-3766	32	15	whereas	whereas	SCONJ
fnp-3766	32	16	ad	ad	NOUN
fnp-3766	32	17	brains	brain	NOUN
fnp-3766	32	18	contain	contain	VERB
fnp-3766	32	19	both	both	CCONJ
fnp-3766	32	20	diffuse	diffuse	ADJ
fnp-3766	32	21	and	and	CCONJ
fnp-3766	32	22	compact	compact	ADJ
fnp-3766	32	23	/	/	SYM
fnp-3766	32	24	neuritic	neuritic	ADJ
fnp-3766	32	25	deposits	deposit	NOUN
fnp-3766	32	26	of	of	ADP
fnp-3766	32	27	aβ	aβ	NOUN
fnp-3766	32	28	(	(	PUNCT
fnp-3766	32	29	26	26	NUM
fnp-3766	32	30	-	-	SYM
fnp-3766	32	31	28	28	NUM
fnp-3766	32	32	)	)	PUNCT
fnp-3766	32	33	.	.	PUNCT
fnp-3766	33	1	cognitively	cognitively	ADV
fnp-3766	33	2	normal	normal	ADJ
fnp-3766	33	3	individuals	individual	NOUN
fnp-3766	33	4	with	with	ADP
fnp-3766	33	5	pa	pa	PROPN
fnp-3766	33	6	generally	generally	ADV
fnp-3766	33	7	have	have	VERB
fnp-3766	33	8	very	very	ADV
fnp-3766	33	9	low	low	ADJ
fnp-3766	33	10	levels	level	NOUN
fnp-3766	33	11	of	of	ADP
fnp-3766	33	12	tau	tau	PROPN
fnp-3766	33	13	pathology	pathology	NOUN
fnp-3766	33	14	(	(	PUNCT
fnp-3766	33	15	26	26	NUM
fnp-3766	33	16	)	)	PUNCT
fnp-3766	33	17	.	.	PUNCT
fnp-3766	34	1	rigorous	rigorous	ADJ
fnp-3766	34	2	biochemical	biochemical	ADJ
fnp-3766	34	3	examination	examination	NOUN
fnp-3766	34	4	of	of	ADP
fnp-3766	34	5	aβ	aβ	PRON
fnp-3766	34	6	from	from	ADP
fnp-3766	34	7	the	the	DET
fnp-3766	34	8	pre	pre	ADJ
fnp-3766	34	9	-	-	ADJ
fnp-3766	34	10	frontal	frontal	ADJ
fnp-3766	34	11	cortex	cortex	NOUN
fnp-3766	34	12	of	of	ADP
fnp-3766	34	13	pa	pa	PROPN
fnp-3766	34	14	and	and	CCONJ
fnp-3766	34	15	ad	ad	NOUN
fnp-3766	34	16	brain	brain	NOUN
fnp-3766	34	17	revealed	reveal	VERB
fnp-3766	34	18	extensive	extensive	ADJ
fnp-3766	34	19	overlap	overlap	NOUN
fnp-3766	34	20	in	in	ADP
fnp-3766	34	21	aβ	aβ	DET
fnp-3766	34	22	levels	level	NOUN
fnp-3766	34	23	,	,	PUNCT
fnp-3766	34	24	peptide	peptide	NOUN
fnp-3766	34	25	profiles	profile	NOUN
fnp-3766	34	26	,	,	PUNCT
fnp-3766	34	27	solubility	solubility	NOUN
fnp-3766	34	28	,	,	PUNCT
fnp-3766	34	29	and	and	CCONJ
fnp-3766	34	30	sds	sds	NOUN
fnp-3766	34	31	-	-	PUNCT
fnp-3766	34	32	stable	stable	ADJ
fnp-3766	34	33	oligomeric	oligomeric	ADJ
fnp-3766	34	34	assemblies	assembly	NOUN
fnp-3766	34	35	(	(	PUNCT
fnp-3766	34	36	25	25	NUM
fnp-3766	34	37	)	)	PUNCT
fnp-3766	34	38	.	.	PUNCT
fnp-3766	35	1	thus	thus	ADV
fnp-3766	35	2	,	,	PUNCT
fnp-3766	35	3	pa	pa	PROPN
fnp-3766	35	4	brains	brain	NOUN
fnp-3766	35	5	provide	provide	VERB
fnp-3766	35	6	a	a	DET
fnp-3766	35	7	source	source	NOUN
fnp-3766	35	8	of	of	ADP
fnp-3766	35	9	human	human	ADJ
fnp-3766	35	10	brain	brain	NOUN
fnp-3766	35	11	-	-	PUNCT
fnp-3766	35	12	derived	derive	VERB
fnp-3766	35	13	aβ	aβ	NOUN
fnp-3766	35	14	seeds	seed	NOUN
fnp-3766	35	15	that	that	PRON
fnp-3766	35	16	can	can	AUX
fnp-3766	35	17	be	be	AUX
fnp-3766	35	18	compared	compare	VERB
fnp-3766	35	19	to	to	ADP
fnp-3766	35	20	human	human	ADJ
fnp-3766	35	21	ad	ad	NOUN
fnp-3766	35	22	brain	brain	NOUN
fnp-3766	35	23	preparations	preparation	NOUN
fnp-3766	35	24	that	that	PRON
fnp-3766	35	25	contain	contain	VERB
fnp-3766	35	26	both	both	PRON
fnp-3766	35	27	aβ	aβ	NOUN
fnp-3766	35	28	and	and	CCONJ
fnp-3766	35	29	tau	tau	PROPN
fnp-3766	35	30	seeds	seed	NOUN
fnp-3766	35	31	.	.	PUNCT
fnp-3766	36	1	nearly	nearly	ADV
fnp-3766	36	2	all	all	PRON
fnp-3766	36	3	of	of	ADP
fnp-3766	36	4	the	the	DET
fnp-3766	36	5	published	publish	VERB
fnp-3766	36	6	studies	study	NOUN
fnp-3766	36	7	involving	involve	VERB
fnp-3766	36	8	injection	injection	NOUN
fnp-3766	36	9	of	of	ADP
fnp-3766	36	10	aβ	aβ	PROPN
fnp-3766	36	11	,	,	PUNCT
fnp-3766	36	12	tau	tau	PROPN
fnp-3766	36	13	,	,	PUNCT
fnp-3766	36	14	or	or	CCONJ
fnp-3766	36	15	αsyn	αsyn	ADJ
fnp-3766	36	16	seeds	seed	NOUN
fnp-3766	36	17	into	into	ADP
fnp-3766	36	18	the	the	DET
fnp-3766	36	19	brains	brain	NOUN
fnp-3766	36	20	of	of	ADP
fnp-3766	36	21	transgenic	transgenic	NOUN
fnp-3766	36	22	mice	mouse	NOUN
fnp-3766	36	23	have	have	AUX
fnp-3766	36	24	followed	follow	VERB
fnp-3766	36	25	a	a	DET
fnp-3766	36	26	protocol	protocol	NOUN
fnp-3766	36	27	of	of	ADP
fnp-3766	36	28	injecting	inject	VERB
fnp-3766	36	29	the	the	DET
fnp-3766	36	30	seeds	seed	NOUN
fnp-3766	36	31	stereotaxically	stereotaxically	ADV
fnp-3766	36	32	into	into	ADP
fnp-3766	36	33	the	the	DET
fnp-3766	36	34	brains	brain	NOUN
fnp-3766	36	35	of	of	ADP
fnp-3766	36	36	young	young	ADJ
fnp-3766	36	37	adult	adult	NOUN
fnp-3766	36	38	mice	mouse	NOUN
fnp-3766	36	39	.	.	PUNCT
fnp-3766	37	1	in	in	ADP
fnp-3766	37	2	this	this	DET
fnp-3766	37	3	study	study	NOUN
fnp-3766	37	4	,	,	PUNCT
fnp-3766	37	5	we	we	PRON
fnp-3766	37	6	have	have	AUX
fnp-3766	37	7	examined	examine	VERB
fnp-3766	37	8	the	the	DET
fnp-3766	37	9	efficacy	efficacy	NOUN
fnp-3766	37	10	of	of	ADP
fnp-3766	37	11	intracerebroventricular	intracerebroventricular	ADJ
fnp-3766	37	12	injection	injection	NOUN
fnp-3766	37	13	of	of	ADP
fnp-3766	37	14	homogenates	homogenate	NOUN
fnp-3766	37	15	prepared	prepare	VERB
fnp-3766	37	16	from	from	ADP
fnp-3766	37	17	ad	ad	NOUN
fnp-3766	37	18	,	,	PUNCT
fnp-3766	37	19	pa	pa	PROPN
fnp-3766	37	20	,	,	PUNCT
fnp-3766	37	21	and	and	CCONJ
fnp-3766	37	22	ad	ad	NOUN
fnp-3766	37	23	/	/	SYM
fnp-3766	37	24	lbd	lbd	NOUN
fnp-3766	37	25	donors	donor	NOUN
fnp-3766	37	26	into	into	ADP
fnp-3766	37	27	newborn	newborn	ADJ
fnp-3766	37	28	app	app	NOUN
fnp-3766	37	29	,	,	PUNCT
fnp-3766	37	30	app	app	PROPN
fnp-3766	37	31	/	/	SYM
fnp-3766	37	32	tau	tau	PROPN
fnp-3766	37	33	,	,	PUNCT
fnp-3766	37	34	or	or	CCONJ
fnp-3766	37	35	app	app	ADJ
fnp-3766	37	36	/	/	SYM
fnp-3766	37	37	αsyn	αsyn	NOUN
fnp-3766	37	38	host	host	NOUN
fnp-3766	37	39	mice	mouse	NOUN
fnp-3766	37	40	.	.	PUNCT
fnp-3766	38	1	in	in	ADP
fnp-3766	38	2	prior	prior	ADJ
fnp-3766	38	3	studies	study	NOUN
fnp-3766	38	4	,	,	PUNCT
fnp-3766	38	5	we	we	PRON
fnp-3766	38	6	had	have	AUX
fnp-3766	38	7	established	establish	VERB
fnp-3766	38	8	that	that	DET
fnp-3766	38	9	injection	injection	NOUN
fnp-3766	38	10	of	of	ADP
fnp-3766	38	11	recombinant	recombinant	ADJ
fnp-3766	38	12	adeno	adeno	NOUN
fnp-3766	38	13	-	-	PUNCT
fnp-3766	38	14	associated	associate	VERB
fnp-3766	38	15	virus	virus	NOUN
fnp-3766	38	16	into	into	ADP
fnp-3766	38	17	newborn	newborn	ADJ
fnp-3766	38	18	mice	mouse	NOUN
fnp-3766	38	19	was	be	AUX
fnp-3766	38	20	an	an	DET
fnp-3766	38	21	effective	effective	ADJ
fnp-3766	38	22	approach	approach	NOUN
fnp-3766	38	23	to	to	ADP
fnp-3766	38	24	obtaining	obtain	VERB
fnp-3766	38	25	widespread	widespread	ADJ
fnp-3766	38	26	dispersion	dispersion	NOUN
fnp-3766	38	27	of	of	ADP
fnp-3766	38	28	injected	inject	VERB
fnp-3766	38	29	virus	virus	NOUN
fnp-3766	38	30	(	(	PUNCT
fnp-3766	38	31	29	29	NUM
fnp-3766	38	32	,	,	PUNCT
fnp-3766	38	33	30	30	NUM
fnp-3766	38	34	)	)	PUNCT
fnp-3766	38	35	.	.	PUNCT
fnp-3766	39	1	we	we	PRON
fnp-3766	39	2	therefore	therefore	ADV
fnp-3766	39	3	hypothesized	hypothesize	VERB
fnp-3766	39	4	that	that	SCONJ
fnp-3766	39	5	misfolded	misfolde	VERB
fnp-3766	39	6	seeds	seed	NOUN
fnp-3766	39	7	of	of	ADP
fnp-3766	39	8	aβ	aβ	NOUN
fnp-3766	39	9	,	,	PUNCT
fnp-3766	39	10	tau	tau	PROPN
fnp-3766	39	11	,	,	PUNCT
fnp-3766	39	12	or	or	CCONJ
fnp-3766	39	13	αsyn	αsyn	NOUN
fnp-3766	39	14	might	might	AUX
fnp-3766	39	15	similarly	similarly	ADV
fnp-3766	39	16	be	be	AUX
fnp-3766	39	17	more	more	ADV
fnp-3766	39	18	widely	widely	ADV
fnp-3766	39	19	dispersed	disperse	VERB
fnp-3766	39	20	to	to	ADP
fnp-3766	39	21	more	more	ADV
fnp-3766	39	22	effectively	effectively	ADV
fnp-3766	39	23	seed	seed	VERB
fnp-3766	39	24	pathology	pathology	NOUN
fnp-3766	39	25	.	.	PUNCT
fnp-3766	40	1	in	in	ADP
fnp-3766	40	2	fact	fact	NOUN
fnp-3766	40	3	,	,	PUNCT
fnp-3766	40	4	we	we	PRON
fnp-3766	40	5	observed	observe	VERB
fnp-3766	40	6	efficient	efficient	ADJ
fnp-3766	40	7	seeding	seeding	NOUN
fnp-3766	40	8	of	of	ADP
fnp-3766	40	9	αsyn	αsyn	ADJ
fnp-3766	40	10	pathology	pathology	NOUN
fnp-3766	40	11	in	in	ADP
fnp-3766	40	12	newborn	newborn	ADJ
fnp-3766	40	13	mice	mouse	NOUN
fnp-3766	40	14	,	,	PUNCT
fnp-3766	40	15	expressing	express	VERB
fnp-3766	40	16	a53	a53	PROPN
fnp-3766	40	17	t	t	PROPN
fnp-3766	40	18	human	human	ADJ
fnp-3766	40	19	αsyn	αsyn	PROPN
fnp-3766	40	20	(	(	PUNCT
fnp-3766	40	21	m83	m83	NOUN
fnp-3766	40	22	line	line	NOUN
fnp-3766	40	23	)	)	PUNCT
fnp-3766	40	24	,	,	PUNCT
fnp-3766	40	25	by	by	ADP
fnp-3766	40	26	injecting	inject	VERB
fnp-3766	40	27	brain	brain	NOUN
fnp-3766	40	28	lysates	lysate	NOUN
fnp-3766	40	29	from	from	ADP
fnp-3766	40	30	patients	patient	NOUN
fnp-3766	40	31	with	with	ADP
fnp-3766	40	32	multisystem	multisystem	NOUN
fnp-3766	40	33	atrophy	atrophy	NOUN
fnp-3766	40	34	(	(	PUNCT
fnp-3766	40	35	31	31	NUM
fnp-3766	40	36	)	)	PUNCT
fnp-3766	40	37	.	.	PUNCT
fnp-3766	41	1	here	here	ADV
fnp-3766	41	2	we	we	PRON
fnp-3766	41	3	performed	perform	VERB
fnp-3766	41	4	brain	brain	NOUN
fnp-3766	41	5	lysate	lysate	NOUN
fnp-3766	41	6	injection	injection	NOUN
fnp-3766	41	7	studies	study	NOUN
fnp-3766	41	8	at	at	ADP
fnp-3766	41	9	p0	p0	NOUN
fnp-3766	41	10	in	in	ADP
fnp-3766	41	11	the	the	DET
fnp-3766	41	12	lateral	lateral	ADJ
fnp-3766	41	13	ventricles	ventricle	NOUN
fnp-3766	41	14	of	of	ADP
fnp-3766	41	15	host	host	NOUN
fnp-3766	41	16	transgenic	transgenic	NOUN
fnp-3766	41	17	mice	mouse	NOUN
fnp-3766	41	18	that	that	PRON
fnp-3766	41	19	co	co	VERB
fnp-3766	41	20	-	-	ADJ
fnp-3766	41	21	express	express	ADJ
fnp-3766	41	22	humanized	humanize	VERB
fnp-3766	41	23	mutant	mutant	ADJ
fnp-3766	41	24	app	app	NOUN
fnp-3766	41	25	with	with	ADP
fnp-3766	41	26	either	either	CCONJ
fnp-3766	41	27	mutant	mutant	ADJ
fnp-3766	41	28	human	human	PROPN
fnp-3766	41	29	tau	tau	PROPN
fnp-3766	41	30	-	-	PUNCT
fnp-3766	41	31	p301l	p301l	NOUN
fnp-3766	41	32	or	or	CCONJ
fnp-3766	41	33	wild	wild	ADJ
fnp-3766	41	34	-	-	PUNCT
fnp-3766	41	35	type	type	NOUN
fnp-3766	41	36	human	human	ADJ
fnp-3766	41	37	αsyn	αsyn	NOUN
fnp-3766	41	38	(	(	PUNCT
fnp-3766	41	39	m20	m20	NOUN
fnp-3766	41	40	line	line	NOUN
fnp-3766	41	41	)	)	PUNCT
fnp-3766	41	42	.	.	PUNCT
fnp-3766	42	1	importantly	importantly	ADV
fnp-3766	42	2	,	,	PUNCT
fnp-3766	42	3	the	the	DET
fnp-3766	42	4	recipient	recipient	NOUN
fnp-3766	42	5	transgenic	transgenic	NOUN
fnp-3766	42	6	mice	mouse	NOUN
fnp-3766	42	7	used	use	VERB
fnp-3766	42	8	in	in	ADP
fnp-3766	42	9	the	the	DET
fnp-3766	42	10	current	current	ADJ
fnp-3766	42	11	studies	study	NOUN
fnp-3766	42	12	develop	develop	VERB
fnp-3766	42	13	pathology	pathology	NOUN
fnp-3766	42	14	at	at	ADP
fnp-3766	42	15	late	late	ADJ
fnp-3766	42	16	ages	age	NOUN
fnp-3766	42	17	or	or	CCONJ
fnp-3766	42	18	not	not	PART
fnp-3766	42	19	at	at	ADV
fnp-3766	42	20	all	all	ADV
fnp-3766	42	21	;	;	PUNCT
fnp-3766	42	22	enabling	enable	VERB
fnp-3766	42	23	sensitive	sensitive	ADJ
fnp-3766	42	24	evaluation	evaluation	NOUN
fnp-3766	42	25	of	of	ADP
fnp-3766	42	26	potential	potential	ADJ
fnp-3766	42	27	seeding	seeding	NOUN
fnp-3766	42	28	.	.	PUNCT
fnp-3766	43	1	we	we	PRON
fnp-3766	43	2	observed	observe	VERB
fnp-3766	43	3	that	that	SCONJ
fnp-3766	43	4	injecting	inject	VERB
fnp-3766	43	5	newborn	newborn	ADJ
fnp-3766	43	6	app	app	NOUN
fnp-3766	43	7	,	,	PUNCT
fnp-3766	43	8	app	app	PROPN
fnp-3766	43	9	/	/	SYM
fnp-3766	43	10	tau	tau	PROPN
fnp-3766	43	11	,	,	PUNCT
fnp-3766	43	12	or	or	CCONJ
fnp-3766	43	13	app	app	PRON
fnp-3766	43	14	/	/	SYM
fnp-3766	43	15	αsyn	αsyn	NOUN
fnp-3766	43	16	mice	mouse	NOUN
fnp-3766	43	17	with	with	ADP
fnp-3766	43	18	homogenates	homogenate	NOUN
fnp-3766	43	19	from	from	ADP
fnp-3766	43	20	diverse	diverse	ADJ
fnp-3766	43	21	pathological	pathological	ADJ
fnp-3766	43	22	specimens	specimen	NOUN
fnp-3766	43	23	,	,	PUNCT
fnp-3766	43	24	including	include	VERB
fnp-3766	43	25	pa	pa	PROPN
fnp-3766	43	26	brains	brain	NOUN
fnp-3766	43	27	,	,	PUNCT
fnp-3766	43	28	produced	produce	VERB
fnp-3766	43	29	robust	robust	ADJ
fnp-3766	43	30	diffuse	diffuse	NOUN
fnp-3766	43	31	aβ	aβ	ADP
fnp-3766	43	32	deposition	deposition	NOUN
fnp-3766	43	33	.	.	PUNCT
fnp-3766	44	1	though	though	SCONJ
fnp-3766	44	2	the	the	DET
fnp-3766	44	3	human	human	ADJ
fnp-3766	44	4	homogenates	homogenate	NOUN
fnp-3766	44	5	used	use	VERB
fnp-3766	44	6	contained	contain	VERB
fnp-3766	44	7	coexisting	coexist	VERB
fnp-3766	44	8	αsyn	αsyn	NOUN
fnp-3766	44	9	and	and	CCONJ
fnp-3766	44	10	tau	tau	PROPN
fnp-3766	44	11	seeds	seed	NOUN
fnp-3766	44	12	,	,	PUNCT
fnp-3766	44	13	we	we	PRON
fnp-3766	44	14	were	be	AUX
fnp-3766	44	15	not	not	PART
fnp-3766	44	16	able	able	ADJ
fnp-3766	44	17	to	to	PART
fnp-3766	44	18	directly	directly	ADV
fnp-3766	44	19	induce	induce	VERB
fnp-3766	44	20	lbd	lbd	PROPN
fnp-3766	44	21	or	or	CCONJ
fnp-3766	44	22	tau	tau	PROPN
fnp-3766	44	23	pathology	pathology	NOUN
fnp-3766	44	24	in	in	ADP
fnp-3766	44	25	recipient	recipient	NOUN
fnp-3766	44	26	models	model	NOUN
fnp-3766	44	27	tested	test	VERB
fnp-3766	44	28	here	here	ADV
fnp-3766	44	29	.	.	PUNCT
fnp-3766	45	1	we	we	PRON
fnp-3766	45	2	compared	compare	VERB
fnp-3766	45	3	the	the	DET
fnp-3766	45	4	data	datum	NOUN
fnp-3766	45	5	from	from	ADP
fnp-3766	45	6	human	human	ADJ
fnp-3766	45	7	lysates	lysate	NOUN
fnp-3766	45	8	to	to	ADP
fnp-3766	45	9	lysates	lysate	NOUN
fnp-3766	45	10	prepared	prepare	VERB
fnp-3766	45	11	from	from	ADP
fnp-3766	45	12	transgenic	transgenic	NOUN
fnp-3766	45	13	mouse	mouse	NOUN
fnp-3766	45	14	donors	donor	NOUN
fnp-3766	45	15	finding	find	VERB
fnp-3766	45	16	again	again	ADV
fnp-3766	45	17	that	that	SCONJ
fnp-3766	45	18	diffuse	diffuse	VERB
fnp-3766	45	19	aβ	aβ	NOUN
fnp-3766	45	20	deposits	deposit	NOUN
fnp-3766	45	21	were	be	AUX
fnp-3766	45	22	preferentially	preferentially	ADV
fnp-3766	45	23	seeded	seed	VERB
fnp-3766	45	24	when	when	SCONJ
fnp-3766	45	25	these	these	DET
fnp-3766	45	26	preparations	preparation	NOUN
fnp-3766	45	27	were	be	AUX
fnp-3766	45	28	injected	inject	VERB
fnp-3766	45	29	in	in	ADP
fnp-3766	45	30	newborn	newborn	ADJ
fnp-3766	45	31	mice	mouse	NOUN
fnp-3766	45	32	.	.	PUNCT
fnp-3766	46	1	app	app	NOUN
fnp-3766	46	2	mice	mouse	NOUN
fnp-3766	46	3	seeded	seed	VERB
fnp-3766	46	4	with	with	ADP
fnp-3766	46	5	ad	ad	NOUN
fnp-3766	46	6	brain	brain	NOUN
fnp-3766	46	7	lysates	lysate	NOUN
fnp-3766	46	8	,	,	PUNCT
fnp-3766	46	9	exhibiting	exhibit	VERB
fnp-3766	46	10	diffuse	diffuse	NOUN
fnp-3766	46	11	aβ	aβ	DET
fnp-3766	46	12	pathology	pathology	NOUN
fnp-3766	46	13	,	,	PUNCT
fnp-3766	46	14	also	also	ADV
fnp-3766	46	15	showed	show	VERB
fnp-3766	46	16	no	no	DET
fnp-3766	46	17	significant	significant	ADJ
fnp-3766	46	18	impairments	impairment	NOUN
fnp-3766	46	19	in	in	ADP
fnp-3766	46	20	a	a	DET
fnp-3766	46	21	contextual	contextual	ADJ
fnp-3766	46	22	fear	fear	NOUN
fnp-3766	46	23	paradigm	paradigm	NOUN
fnp-3766	46	24	of	of	ADP
fnp-3766	46	25	cognitive	cognitive	ADJ
fnp-3766	46	26	performance	performance	NOUN
fnp-3766	46	27	.	.	PUNCT
fnp-3766	47	1	our	our	PRON
fnp-3766	47	2	findings	finding	NOUN
fnp-3766	47	3	indicate	indicate	VERB
fnp-3766	47	4	that	that	SCONJ
fnp-3766	47	5	the	the	DET
fnp-3766	47	6	injection	injection	NOUN
fnp-3766	47	7	of	of	ADP
fnp-3766	47	8	human	human	ADJ
fnp-3766	47	9	brain	brain	NOUN
fnp-3766	47	10	homogenates	homogenate	NOUN
fnp-3766	47	11	from	from	ADP
fnp-3766	47	12	ad	ad	NOUN
fnp-3766	47	13	and	and	CCONJ
fnp-3766	47	14	ad	ad	NOUN
fnp-3766	47	15	/	/	SYM
fnp-3766	47	16	lbd	lbd	NOUN
fnp-3766	47	17	donors	donor	NOUN
fnp-3766	47	18	into	into	ADP
fnp-3766	47	19	newborn	newborn	ADJ
fnp-3766	47	20	app	app	NOUN
fnp-3766	47	21	mice	mouse	NOUN
fnp-3766	47	22	preferentially	preferentially	ADV
fnp-3766	47	23	induces	induce	VERB
fnp-3766	47	24	diffuse	diffuse	NOUN
fnp-3766	47	25	aβ	aβ	DET
fnp-3766	47	26	pathology	pathology	NOUN
fnp-3766	47	27	.	.	PUNCT
fnp-3766	48	1	interestingly	interestingly	ADV
fnp-3766	48	2	,	,	PUNCT
fnp-3766	48	3	pa	pa	PROPN
fnp-3766	48	4	brains	brain	NOUN
fnp-3766	48	5	induce	induce	VERB
fnp-3766	48	6	the	the	DET
fnp-3766	48	7	same	same	ADJ
fnp-3766	48	8	pathology	pathology	NOUN
fnp-3766	48	9	implying	imply	VERB
fnp-3766	48	10	that	that	SCONJ
fnp-3766	48	11	ad	ad	NOUN
fnp-3766	48	12	and	and	CCONJ
fnp-3766	48	13	ad	ad	NOUN
fnp-3766	48	14	/	/	SYM
fnp-3766	48	15	lbd	lbd	PROPN
fnp-3766	48	16	brains	brain	NOUN
fnp-3766	48	17	contain	contain	VERB
fnp-3766	48	18	amyloid	amyloid	NOUN
fnp-3766	48	19	seeding	seed	VERB
fnp-3766	48	20	entities	entity	NOUN
fnp-3766	48	21	that	that	PRON
fnp-3766	48	22	are	be	AUX
fnp-3766	48	23	shared	share	VERB
fnp-3766	48	24	with	with	ADP
fnp-3766	48	25	pa	pa	PROPN
fnp-3766	48	26	brains	brain	NOUN
fnp-3766	48	27	.	.	PUNCT
fnp-3766	49	1	methods	method	NOUN
fnp-3766	49	2	description	description	NOUN
fnp-3766	49	3	of	of	ADP
fnp-3766	49	4	ad	ad	NOUN
fnp-3766	49	5	,	,	PUNCT
fnp-3766	49	6	pa	pa	PROPN
fnp-3766	49	7	and	and	CCONJ
fnp-3766	49	8	ndc	ndc	NOUN
fnp-3766	49	9	cases	case	NOUN
fnp-3766	49	10	for	for	ADP
fnp-3766	49	11	this	this	DET
fnp-3766	49	12	study	study	NOUN
fnp-3766	49	13	we	we	PRON
fnp-3766	49	14	utilized	utilize	VERB
fnp-3766	49	15	a	a	DET
fnp-3766	49	16	subset	subset	NOUN
fnp-3766	49	17	of	of	ADP
fnp-3766	49	18	the	the	DET
fnp-3766	49	19	human	human	ADJ
fnp-3766	49	20	brain	brain	NOUN
fnp-3766	49	21	samples	sample	NOUN
fnp-3766	49	22	that	that	PRON
fnp-3766	49	23	our	our	PRON
fnp-3766	49	24	group	group	NOUN
fnp-3766	49	25	previously	previously	ADV
fnp-3766	49	26	analyzed	analyze	VERB
fnp-3766	49	27	(	(	PUNCT
fnp-3766	49	28	25	25	NUM
fnp-3766	49	29	)	)	PUNCT
fnp-3766	49	30	.	.	PUNCT
fnp-3766	50	1	tissue	tissue	NOUN
fnp-3766	50	2	sections	section	NOUN
fnp-3766	50	3	and	and	CCONJ
fnp-3766	50	4	frozen	frozen	ADJ
fnp-3766	50	5	pre	pre	ADJ
fnp-3766	50	6	-	-	ADJ
fnp-3766	50	7	frontal	frontal	ADJ
fnp-3766	50	8	cortex	cortex	NOUN
fnp-3766	50	9	(	(	PUNCT
fnp-3766	50	10	ad	ad	NOUN
fnp-3766	50	11	=	=	SYM
fnp-3766	50	12	2	2	NUM
fnp-3766	50	13	,	,	PUNCT
fnp-3766	50	14	pa	pa	PROPN
fnp-3766	50	15	=	=	PROPN
fnp-3766	50	16	4	4	NUM
fnp-3766	50	17	,	,	PUNCT
fnp-3766	50	18	and	and	CCONJ
fnp-3766	50	19	ndc	ndc	NOUN
fnp-3766	50	20	=	=	SYM
fnp-3766	50	21	2	2	NUM
fnp-3766	50	22	)	)	PUNCT
fnp-3766	50	23	were	be	AUX
fnp-3766	50	24	obtained	obtain	VERB
fnp-3766	50	25	from	from	ADP
fnp-3766	50	26	the	the	DET
fnp-3766	50	27	mayo	mayo	PROPN
fnp-3766	50	28	clinic	clinic	PROPN
fnp-3766	50	29	brain	brain	PROPN
fnp-3766	50	30	bank	bank	PROPN
fnp-3766	50	31	with	with	ADP
fnp-3766	50	32	informed	informed	ADJ
fnp-3766	50	33	consent	consent	NOUN
fnp-3766	50	34	,	,	PUNCT
fnp-3766	50	35	in	in	ADP
fnp-3766	50	36	accordance	accordance	NOUN
fnp-3766	50	37	with	with	ADP
fnp-3766	50	38	the	the	DET
fnp-3766	50	39	mayo	mayo	NOUN
fnp-3766	50	40	clinic	clinic	PROPN
fnp-3766	50	41	institutional	institutional	PROPN
fnp-3766	50	42	review	review	PROPN
fnp-3766	50	43	board	board	NOUN
fnp-3766	50	44	,	,	PUNCT
fnp-3766	50	45	using	use	VERB
fnp-3766	50	46	previously	previously	ADV
fnp-3766	50	47	described	describe	VERB
fnp-3766	50	48	acquisition	acquisition	NOUN
fnp-3766	50	49	and	and	CCONJ
fnp-3766	50	50	diagnostic	diagnostic	ADJ
fnp-3766	50	51	analyses	analysis	NOUN
fnp-3766	50	52	(	(	PUNCT
fnp-3766	50	53	26	26	NUM
fnp-3766	50	54	,	,	PUNCT
fnp-3766	50	55	32	32	NUM
fnp-3766	50	56	,	,	PUNCT
fnp-3766	50	57	33	33	NUM
fnp-3766	50	58	)	)	PUNCT
fnp-3766	50	59	.	.	PUNCT
fnp-3766	51	1	samples	sample	NOUN
fnp-3766	51	2	were	be	AUX
fnp-3766	51	3	initially	initially	ADV
fnp-3766	51	4	cryo	cryo	NOUN
fnp-3766	51	5	-	-	PUNCT
fnp-3766	51	6	pulverized	pulverize	VERB
fnp-3766	51	7	to	to	PART
fnp-3766	51	8	allow	allow	VERB
fnp-3766	51	9	for	for	ADP
fnp-3766	51	10	multiple	multiple	ADJ
fnp-3766	51	11	studies	study	NOUN
fnp-3766	51	12	.	.	PUNCT
fnp-3766	52	1	we	we	PRON
fnp-3766	52	2	previously	previously	ADV
fnp-3766	52	3	analyzed	analyze	VERB
fnp-3766	52	4	the	the	DET
fnp-3766	52	5	aβ	aβ	PROPN
fnp-3766	52	6	peptide	peptide	NOUN
fnp-3766	52	7	profile	profile	NOUN
fnp-3766	52	8	,	,	PUNCT
fnp-3766	52	9	quantity	quantity	NOUN
fnp-3766	52	10	,	,	PUNCT
fnp-3766	52	11	and	and	CCONJ
fnp-3766	52	12	solubility	solubility	NOUN
fnp-3766	52	13	in	in	ADP
fnp-3766	52	14	these	these	DET
fnp-3766	52	15	brain	brain	NOUN
fnp-3766	52	16	samples	sample	NOUN
fnp-3766	52	17	(	(	PUNCT
fnp-3766	52	18	25	25	NUM
fnp-3766	52	19	)	)	PUNCT
fnp-3766	52	20	.	.	PUNCT
fnp-3766	53	1	in	in	ADP
fnp-3766	53	2	this	this	DET
fnp-3766	53	3	study	study	NOUN
fnp-3766	53	4	,	,	PUNCT
fnp-3766	53	5	we	we	PRON
fnp-3766	53	6	analyzed	analyze	VERB
fnp-3766	53	7	two	two	NUM
fnp-3766	53	8	brains	brain	NOUN
fnp-3766	53	9	from	from	ADP
fnp-3766	53	10	ad	ad	NOUN
fnp-3766	53	11	patients	patient	NOUN
fnp-3766	53	12	(	(	PUNCT
fnp-3766	53	13	both	both	PRON
fnp-3766	53	14	aged	aged	ADJ
fnp-3766	53	15	84	84	NUM
fnp-3766	53	16	)	)	PUNCT
fnp-3766	53	17	,	,	PUNCT
fnp-3766	53	18	four	four	NUM
fnp-3766	53	19	pa	pa	PROPN
fnp-3766	53	20	brains	brain	NOUN
fnp-3766	53	21	from	from	ADP
fnp-3766	53	22	subjects	subject	NOUN
fnp-3766	53	23	(	(	PUNCT
fnp-3766	53	24	age	age	NOUN
fnp-3766	53	25	range	range	NOUN
fnp-3766	53	26	=	=	SYM
fnp-3766	53	27	78	78	NUM
fnp-3766	53	28	to	to	PART
fnp-3766	53	29	83	83	NUM
fnp-3766	53	30	)	)	PUNCT
fnp-3766	53	31	without	without	ADP
fnp-3766	53	32	clinical	clinical	ADJ
fnp-3766	53	33	evidence	evidence	NOUN
fnp-3766	53	34	of	of	ADP
fnp-3766	53	35	dementia	dementia	NOUN
fnp-3766	53	36	,	,	PUNCT
fnp-3766	53	37	and	and	CCONJ
fnp-3766	53	38	two	two	NUM
fnp-3766	53	39	brains	brain	NOUN
fnp-3766	53	40	with	with	ADP
fnp-3766	53	41	rare	rare	ADJ
fnp-3766	53	42	or	or	CCONJ
fnp-3766	53	43	no	no	PRON
fnp-3766	53	44	ad	ad	NOUN
fnp-3766	53	45	lesions	lesion	NOUN
fnp-3766	53	46	from	from	ADP
fnp-3766	53	47	elderly	elderly	ADJ
fnp-3766	53	48	individuals	individual	NOUN
fnp-3766	53	49	without	without	ADP
fnp-3766	53	50	clinical	clinical	ADJ
fnp-3766	53	51	evidence	evidence	NOUN
fnp-3766	53	52	of	of	ADP
fnp-3766	53	53	a	a	DET
fnp-3766	53	54	neurological	neurological	ADJ
fnp-3766	53	55	illness	illness	NOUN
fnp-3766	53	56	(	(	PUNCT
fnp-3766	53	57	ages	age	NOUN
fnp-3766	53	58	75	75	NUM
fnp-3766	53	59	and	and	CCONJ
fnp-3766	53	60	78	78	NUM
fnp-3766	53	61	)	)	PUNCT
fnp-3766	53	62	.	.	PUNCT
fnp-3766	54	1	in	in	ADP
fnp-3766	54	2	addition	addition	NOUN
fnp-3766	54	3	,	,	PUNCT
fnp-3766	54	4	human	human	ADJ
fnp-3766	54	5	brain	brain	NOUN
fnp-3766	54	6	samples	sample	NOUN
fnp-3766	54	7	were	be	AUX
fnp-3766	54	8	also	also	ADV
fnp-3766	54	9	obtained	obtain	VERB
fnp-3766	54	10	from	from	ADP
fnp-3766	54	11	the	the	DET
fnp-3766	54	12	university	university	PROPN
fnp-3766	54	13	of	of	ADP
fnp-3766	54	14	florida	florida	PROPN
fnp-3766	54	15	neuromedicine	neuromedicine	PROPN
fnp-3766	54	16	human	human	ADJ
fnp-3766	54	17	brain	brain	NOUN
fnp-3766	54	18	tissue	tissue	NOUN
fnp-3766	54	19	bank	bank	NOUN
fnp-3766	54	20	following	follow	VERB
fnp-3766	54	21	institutional	institutional	ADJ
fnp-3766	54	22	regulations	regulation	NOUN
fnp-3766	54	23	and	and	CCONJ
fnp-3766	54	24	previously	previously	ADV
fnp-3766	54	25	described	describe	VERB
fnp-3766	54	26	classification	classification	NOUN
fnp-3766	54	27	(	(	PUNCT
fnp-3766	54	28	34	34	NUM
fnp-3766	54	29	-	-	SYM
fnp-3766	54	30	36	36	NUM
fnp-3766	54	31	)	)	PUNCT
fnp-3766	54	32	.	.	PUNCT
fnp-3766	55	1	we	we	PRON
fnp-3766	55	2	analyzed	analyze	VERB
fnp-3766	55	3	tissue	tissue	NOUN
fnp-3766	55	4	sections	section	NOUN
fnp-3766	55	5	and	and	CCONJ
fnp-3766	55	6	frozen	frozen	ADJ
fnp-3766	55	7	pre	pre	ADJ
fnp-3766	55	8	-	-	ADJ
fnp-3766	55	9	frontal	frontal	ADJ
fnp-3766	55	10	cortex	cortex	NOUN
fnp-3766	55	11	from	from	ADP
fnp-3766	55	12	two	two	NUM
fnp-3766	55	13	ad	ad	NOUN
fnp-3766	55	14	patients	patient	NOUN
fnp-3766	55	15	(	(	PUNCT
fnp-3766	55	16	ages	age	NOUN
fnp-3766	55	17	82	82	NUM
fnp-3766	55	18	and	and	CCONJ
fnp-3766	55	19	86	86	NUM
fnp-3766	55	20	)	)	PUNCT
fnp-3766	55	21	,	,	PUNCT
fnp-3766	55	22	two	two	NUM
fnp-3766	55	23	cases	case	NOUN
fnp-3766	55	24	with	with	ADP
fnp-3766	55	25	ad	ad	NOUN
fnp-3766	55	26	/	/	SYM
fnp-3766	55	27	lbd	lbd	PROPN
fnp-3766	55	28	(	(	PUNCT
fnp-3766	55	29	ages	age	NOUN
fnp-3766	55	30	81	81	NUM
fnp-3766	55	31	and	and	CCONJ
fnp-3766	55	32	83	83	NUM
fnp-3766	55	33	)	)	PUNCT
fnp-3766	55	34	,	,	PUNCT
fnp-3766	55	35	and	and	CCONJ
fnp-3766	55	36	two	two	NUM
fnp-3766	55	37	control	control	NOUN
fnp-3766	55	38	individuals	individual	NOUN
fnp-3766	55	39	without	without	ADP
fnp-3766	55	40	pathology	pathology	NOUN
fnp-3766	55	41	(	(	PUNCT
fnp-3766	55	42	ages	age	NOUN
fnp-3766	55	43	52	52	NUM
fnp-3766	55	44	and	and	CCONJ
fnp-3766	55	45	82	82	NUM
fnp-3766	55	46	)	)	PUNCT
fnp-3766	55	47	.	.	PUNCT
fnp-3766	56	1	table	table	NOUN
fnp-3766	56	2	1	1	NUM
fnp-3766	56	3	summarizes	summarize	NOUN
fnp-3766	56	4	the	the	DET
fnp-3766	56	5	cases	case	NOUN
fnp-3766	56	6	studied	study	VERB
fnp-3766	56	7	in	in	ADP
fnp-3766	56	8	this	this	DET
fnp-3766	56	9	report	report	NOUN
fnp-3766	56	10	.	.	PUNCT
fnp-3766	57	1	table	table	NOUN
fnp-3766	57	2	1	1	NUM
fnp-3766	57	3	.	.	X
fnp-3766	57	4	list	list	NOUN
fnp-3766	57	5	of	of	ADP
fnp-3766	57	6	human	human	ADJ
fnp-3766	57	7	brain	brain	NOUN
fnp-3766	57	8	samples	sample	NOUN
fnp-3766	57	9	used	use	VERB
fnp-3766	57	10	in	in	ADP
fnp-3766	57	11	this	this	DET
fnp-3766	57	12	study	study	NOUN
fnp-3766	57	13	.	.	PUNCT
fnp-3766	58	1	pathological	pathological	ADJ
fnp-3766	58	2	diagnosis	diagnosis	NOUN
fnp-3766	58	3	(	(	PUNCT
fnp-3766	58	4	pathdx	pathdx	NOUN
fnp-3766	58	5	)	)	PUNCT
fnp-3766	58	6	,	,	PUNCT
fnp-3766	58	7	lewy	lewy	PROPN
fnp-3766	58	8	body	body	NOUN
fnp-3766	58	9	disease	disease	NOUN
fnp-3766	58	10	(	(	PUNCT
fnp-3766	58	11	lbd	lbd	PROPN
fnp-3766	58	12	)	)	PUNCT
fnp-3766	58	13	classification	classification	NOUN
fnp-3766	58	14	,	,	PUNCT
fnp-3766	58	15	amyloid	amyloid	NOUN
fnp-3766	58	16	plaque	plaque	NOUN
fnp-3766	58	17	score	score	NOUN
fnp-3766	58	18	(	(	PUNCT
fnp-3766	58	19	thal	thal	NOUN
fnp-3766	58	20	phase	phase	NOUN
fnp-3766	58	21	)	)	PUNCT
fnp-3766	58	22	,	,	PUNCT
fnp-3766	58	23	braak	braak	NOUN
fnp-3766	58	24	stage	stage	NOUN
fnp-3766	58	25	,	,	PUNCT
fnp-3766	58	26	consortium	consortium	NOUN
fnp-3766	58	27	to	to	PART
fnp-3766	58	28	establish	establish	VERB
fnp-3766	58	29	a	a	DET
fnp-3766	58	30	registry	registry	NOUN
fnp-3766	58	31	for	for	ADP
fnp-3766	58	32	alzheimer	alzheimer	PROPN
fnp-3766	58	33	’s	’s	PART
fnp-3766	58	34	disease	disease	NOUN
fnp-3766	58	35	(	(	PUNCT
fnp-3766	58	36	cerad	cerad	PROPN
fnp-3766	58	37	)	)	PUNCT
fnp-3766	58	38	protocol	protocol	NOUN
fnp-3766	58	39	,	,	PUNCT
fnp-3766	58	40	2	2	NUM
fnp-3766	58	41	%	%	NOUN
fnp-3766	58	42	sds	sds	NOUN
fnp-3766	58	43	and	and	CCONJ
fnp-3766	58	44	70	70	NUM
fnp-3766	58	45	%	%	NOUN
fnp-3766	58	46	formic	formic	ADJ
fnp-3766	58	47	acid	acid	NOUN
fnp-3766	58	48	(	(	PUNCT
fnp-3766	58	49	fa	fa	NOUN
fnp-3766	58	50	)	)	PUNCT
fnp-3766	58	51	solubilized	solubilize	VERB
fnp-3766	58	52	aβ40	aβ40	PROPN
fnp-3766	58	53	and	and	CCONJ
fnp-3766	58	54	42	42	NUM
fnp-3766	58	55	(	(	PUNCT
fnp-3766	58	56	25	25	NUM
fnp-3766	58	57	)	)	PUNCT
fnp-3766	58	58	,	,	PUNCT
fnp-3766	58	59	cerebral	cerebral	ADJ
fnp-3766	58	60	amyloid	amyloid	NOUN
fnp-3766	58	61	angiopathy	angiopathy	ADJ
fnp-3766	58	62	(	(	PUNCT
fnp-3766	58	63	caa	caa	NOUN
fnp-3766	58	64	)	)	PUNCT
fnp-3766	58	65	,	,	PUNCT
fnp-3766	58	66	apolipoprotein	apolipoprotein	ADJ
fnp-3766	58	67	e	e	PROPN
fnp-3766	58	68	(	(	PUNCT
fnp-3766	58	69	apoe	apoe	ADJ
fnp-3766	58	70	)	)	PUNCT
fnp-3766	58	71	genotype	genotype	NOUN
fnp-3766	58	72	,	,	PUNCT
fnp-3766	58	73	gender	gender	NOUN
fnp-3766	58	74	,	,	PUNCT
fnp-3766	58	75	and	and	CCONJ
fnp-3766	58	76	age	age	NOUN
fnp-3766	58	77	are	be	AUX
fnp-3766	58	78	reported	report	VERB
fnp-3766	58	79	.	.	PUNCT
fnp-3766	59	1	ad	ad	NOUN
fnp-3766	59	2	,	,	PUNCT
fnp-3766	59	3	alzheimer	alzheimer	PROPN
fnp-3766	59	4	’s	’s	PART
fnp-3766	59	5	disease	disease	NOUN
fnp-3766	59	6	;	;	PUNCT
fnp-3766	59	7	pa	pa	PROPN
fnp-3766	59	8	,	,	PUNCT
fnp-3766	59	9	pathological	pathological	ADJ
fnp-3766	59	10	aging	aging	NOUN
fnp-3766	59	11	;	;	PUNCT
fnp-3766	59	12	ndc	ndc	NOUN
fnp-3766	59	13	,	,	PUNCT
fnp-3766	59	14	non	non	ADJ
fnp-3766	59	15	-	-	ADJ
fnp-3766	59	16	demented	demented	ADJ
fnp-3766	59	17	controls	control	NOUN
fnp-3766	59	18	;	;	PUNCT
fnp-3766	59	19	oa	oa	INTJ
fnp-3766	59	20	,	,	PUNCT
fnp-3766	59	21	optic	optic	ADJ
fnp-3766	59	22	atrophy	atrophy	NOUN
fnp-3766	59	23	;	;	PUNCT
fnp-3766	59	24	tr	tr	VERB
fnp-3766	59	25	,	,	PUNCT
fnp-3766	59	26	transynaptic	transynaptic	ADJ
fnp-3766	59	27	degeneration	degeneration	NOUN
fnp-3766	59	28	;	;	PUNCT
fnp-3766	59	29	gba	gba	NOUN
fnp-3766	59	30	,	,	PUNCT
fnp-3766	59	31	gross	gross	ADJ
fnp-3766	59	32	brain	brain	NOUN
fnp-3766	59	33	atrophy	atrophy	NOUN
fnp-3766	59	34	;	;	PUNCT
fnp-3766	59	35	x	x	X
fnp-3766	59	36	,	,	PUNCT
fnp-3766	59	37	below	below	ADP
fnp-3766	59	38	detection	detection	NOUN
fnp-3766	59	39	levels	level	NOUN
fnp-3766	59	40	;	;	PUNCT
fnp-3766	59	41	nd	nd	X
fnp-3766	59	42	,	,	PUNCT
fnp-3766	59	43	not	not	PART
fnp-3766	59	44	determined	determine	VERB
fnp-3766	59	45	,	,	PUNCT
fnp-3766	59	46	f	f	X
fnp-3766	59	47	,	,	PUNCT
fnp-3766	59	48	female	female	NOUN
fnp-3766	59	49	;	;	PUNCT
fnp-3766	59	50	m	m	NOUN
fnp-3766	59	51	,	,	PUNCT
fnp-3766	59	52	male	male	NOUN
fnp-3766	59	53	.	.	PUNCT
fnp-3766	60	1	transgenic	transgenic	NOUN
fnp-3766	60	2	mice	mouse	NOUN
fnp-3766	60	3	the	the	DET
fnp-3766	60	4	transgenic	transgenic	NOUN
fnp-3766	60	5	mice	mouse	NOUN
fnp-3766	60	6	used	use	VERB
fnp-3766	60	7	in	in	ADP
fnp-3766	60	8	this	this	DET
fnp-3766	60	9	study	study	NOUN
fnp-3766	60	10	have	have	AUX
fnp-3766	60	11	been	be	AUX
fnp-3766	60	12	described	describe	VERB
fnp-3766	60	13	previously	previously	ADV
fnp-3766	60	14	and	and	CCONJ
fnp-3766	60	15	are	be	AUX
fnp-3766	60	16	summarized	summarize	VERB
fnp-3766	60	17	in	in	ADP
fnp-3766	60	18	table	table	NOUN
fnp-3766	60	19	2	2	NUM
fnp-3766	60	20	.	.	PUNCT
fnp-3766	61	1	the	the	DET
fnp-3766	61	2	prp.appsi	prp.appsi	PROPN
fnp-3766	61	3	mice	mouse	NOUN
fnp-3766	61	4	express	express	VERB
fnp-3766	61	5	mouse	mouse	NOUN
fnp-3766	61	6	app-695	app-695	NOUN
fnp-3766	61	7	cdna	cdna	PROPN
fnp-3766	61	8	with	with	ADP
fnp-3766	61	9	a	a	DET
fnp-3766	61	10	humanized	humanize	VERB
fnp-3766	61	11	aβ	aβ	NOUN
fnp-3766	61	12	sequence	sequence	NOUN
fnp-3766	61	13	and	and	CCONJ
fnp-3766	61	14	fad	fad	NOUN
fnp-3766	61	15	mutations	mutation	NOUN
fnp-3766	61	16	(	(	PUNCT
fnp-3766	61	17	appswe	appswe	NOUN
fnp-3766	61	18	/	/	SYM
fnp-3766	61	19	ind	ind	NOUN
fnp-3766	61	20	)	)	PUNCT
fnp-3766	61	21	using	use	VERB
fnp-3766	61	22	the	the	DET
fnp-3766	61	23	moprp.xho	moprp.xho	ADJ
fnp-3766	61	24	vector	vector	NOUN
fnp-3766	61	25	,	,	PUNCT
fnp-3766	61	26	which	which	PRON
fnp-3766	61	27	was	be	AUX
fnp-3766	61	28	co	co	VERB
fnp-3766	61	29	-	-	VERB
fnp-3766	61	30	injected	inject	VERB
fnp-3766	61	31	with	with	ADP
fnp-3766	61	32	a	a	DET
fnp-3766	61	33	vector	vector	NOUN
fnp-3766	61	34	to	to	PART
fnp-3766	61	35	express	express	VERB
fnp-3766	61	36	egfp	egfp	NOUN
fnp-3766	61	37	in	in	ADP
fnp-3766	61	38	skin	skin	NOUN
fnp-3766	61	39	(	(	PUNCT
fnp-3766	61	40	first	first	ADV
fnp-3766	61	41	described	describe	VERB
fnp-3766	61	42	in	in	ADP
fnp-3766	61	43	(	(	PUNCT
fnp-3766	61	44	37	37	NUM
fnp-3766	61	45	)	)	PUNCT
fnp-3766	61	46	)	)	PUNCT
fnp-3766	61	47	.	.	PUNCT
fnp-3766	62	1	the	the	DET
fnp-3766	62	2	itau	itau	NOUN
fnp-3766	62	3	-	-	PUNCT
fnp-3766	62	4	p301l	p301l	NOUN
fnp-3766	62	5	mice	mouse	NOUN
fnp-3766	62	6	express	express	VERB
fnp-3766	62	7	human	human	ADJ
fnp-3766	62	8	0n4r	0n4r	NOUN
fnp-3766	62	9	tau	tau	PROPN
fnp-3766	62	10	-	-	PUNCT
fnp-3766	62	11	p301l	p301l	NOUN
fnp-3766	62	12	using	use	VERB
fnp-3766	62	13	a	a	DET
fnp-3766	62	14	tet	tet	NOUN
fnp-3766	62	15	-	-	PUNCT
fnp-3766	62	16	regulated	regulate	VERB
fnp-3766	62	17	vector	vector	NOUN
fnp-3766	62	18	that	that	PRON
fnp-3766	62	19	includes	include	VERB
fnp-3766	62	20	a	a	DET
fnp-3766	62	21	minimal	minimal	ADJ
fnp-3766	62	22	cmv	cmv	NOUN
fnp-3766	62	23	promoter	promoter	NOUN
fnp-3766	62	24	(	(	PUNCT
fnp-3766	62	25	38	38	NUM
fnp-3766	62	26	)	)	PUNCT
fnp-3766	62	27	.	.	PUNCT
fnp-3766	63	1	tau	tau	PROPN
fnp-3766	63	2	levels	level	NOUN
fnp-3766	63	3	were	be	AUX
fnp-3766	63	4	assessed	assess	VERB
fnp-3766	63	5	by	by	ADP
fnp-3766	63	6	western	western	ADJ
fnp-3766	63	7	blotting	blotting	NOUN
fnp-3766	63	8	.	.	PUNCT
fnp-3766	64	1	pbs	pbs	PROPN
fnp-3766	64	2	lysates	lysate	NOUN
fnp-3766	64	3	of	of	ADP
fnp-3766	64	4	2.5	2.5	NUM
fnp-3766	64	5	-	-	SYM
fnp-3766	64	6	6	6	NUM
fnp-3766	64	7	month	month	NOUN
fnp-3766	64	8	old	old	ADJ
fnp-3766	64	9	p301l	p301l	NOUN
fnp-3766	64	10	mice	mouse	NOUN
fnp-3766	64	11	were	be	AUX
fnp-3766	64	12	heated	heat	VERB
fnp-3766	64	13	at	at	ADP
fnp-3766	64	14	95	95	NUM
fnp-3766	64	15	°	°	ADP
fnp-3766	64	16	c	c	NOUN
fnp-3766	64	17	for	for	ADP
fnp-3766	64	18	five	five	NUM
fnp-3766	64	19	minutes	minute	NOUN
fnp-3766	64	20	in	in	ADP
fnp-3766	64	21	the	the	DET
fnp-3766	64	22	presence	presence	NOUN
fnp-3766	64	23	of	of	ADP
fnp-3766	64	24	denaturing	denature	VERB
fnp-3766	64	25	sds	sds	PROPN
fnp-3766	64	26	sample	sample	NOUN
fnp-3766	64	27	buffer	buffer	NOUN
fnp-3766	64	28	,	,	PUNCT
fnp-3766	64	29	were	be	AUX
fnp-3766	64	30	separated	separate	VERB
fnp-3766	64	31	on	on	ADP
fnp-3766	64	32	a	a	DET
fnp-3766	64	33	4	4	NUM
fnp-3766	64	34	-	-	SYM
fnp-3766	64	35	12	12	NUM
fnp-3766	64	36	%	%	NOUN
fnp-3766	64	37	bis	bis	ADJ
fnp-3766	64	38	-	-	ADJ
fnp-3766	64	39	tris	tris	ADJ
fnp-3766	64	40	gel	gel	NOUN
fnp-3766	64	41	(	(	PUNCT
fnp-3766	64	42	bio	bio	NOUN
fnp-3766	64	43	-	-	PUNCT
fnp-3766	64	44	rad	rad	PROPN
fnp-3766	64	45	,	,	PUNCT
fnp-3766	64	46	hercules	hercule	NOUN
fnp-3766	64	47	,	,	PUNCT
fnp-3766	64	48	ca	ca	NOUN
fnp-3766	64	49	)	)	PUNCT
fnp-3766	64	50	in	in	ADP
fnp-3766	64	51	3-(n	3-(n	NUM
fnp-3766	64	52	-	-	SYM
fnp-3766	64	53	morpholino)propanesulfonic	morpholino)propanesulfonic	ADJ
fnp-3766	64	54	acid	acid	NOUN
fnp-3766	64	55	(	(	PUNCT
fnp-3766	64	56	mops	mop	NOUN
fnp-3766	64	57	)	)	PUNCT
fnp-3766	64	58	running	run	VERB
fnp-3766	64	59	buffer	buffer	NOUN
fnp-3766	64	60	(	(	PUNCT
fnp-3766	64	61	bio	bio	NOUN
fnp-3766	64	62	-	-	ADJ
fnp-3766	64	63	rad	rad	PROPN
fnp-3766	64	64	,	,	PUNCT
fnp-3766	64	65	hercules	hercule	NOUN
fnp-3766	64	66	,	,	PUNCT
fnp-3766	64	67	ca	ca	NOUN
fnp-3766	64	68	)	)	PUNCT
fnp-3766	64	69	and	and	CCONJ
fnp-3766	64	70	transferred	transfer	VERB
fnp-3766	64	71	onto	onto	ADP
fnp-3766	64	72	pvdf	pvdf	PROPN
fnp-3766	64	73	membrane	membrane	NOUN
fnp-3766	64	74	.	.	PUNCT
fnp-3766	65	1	the	the	DET
fnp-3766	65	2	membrane	membrane	NOUN
fnp-3766	65	3	was	be	AUX
fnp-3766	65	4	blocked	block	VERB
fnp-3766	65	5	in	in	ADP
fnp-3766	65	6	casein	casein	NOUN
fnp-3766	65	7	blocking	blocking	NOUN
fnp-3766	65	8	buffer	buffer	NOUN
fnp-3766	65	9	and	and	CCONJ
fnp-3766	65	10	incubated	incubate	VERB
fnp-3766	65	11	overnight	overnight	ADV
fnp-3766	65	12	at	at	ADP
fnp-3766	65	13	4	4	NUM
fnp-3766	65	14	°	°	ADP
fnp-3766	65	15	c	c	NOUN
fnp-3766	65	16	with	with	ADP
fnp-3766	65	17	primary	primary	ADJ
fnp-3766	65	18	antibodies	antibody	NOUN
fnp-3766	65	19	to	to	ADP
fnp-3766	65	20	tau	tau	PROPN
fnp-3766	65	21	,	,	PUNCT
fnp-3766	65	22	tau-13	tau-13	PROPN
fnp-3766	65	23	(	(	PUNCT
fnp-3766	65	24	anti	anti	ADJ
fnp-3766	65	25	-	-	ADJ
fnp-3766	65	26	human	human	ADJ
fnp-3766	65	27	tau2	tau2	NOUN
fnp-3766	65	28	-	-	PUNCT
fnp-3766	65	29	18	18	NUM
fnp-3766	65	30	;	;	PUNCT
fnp-3766	65	31	covance	covance	NOUN
fnp-3766	65	32	)	)	PUNCT
fnp-3766	65	33	and	and	CCONJ
fnp-3766	65	34	3026	3026	NUM
fnp-3766	65	35	(	(	PUNCT
fnp-3766	65	36	rabbit	rabbit	NOUN
fnp-3766	65	37	polyclonal	polyclonal	ADJ
fnp-3766	65	38	antibody	antibody	NOUN
fnp-3766	65	39	raised	raise	VERB
fnp-3766	65	40	against	against	ADP
fnp-3766	65	41	full	full	ADJ
fnp-3766	65	42	length	length	NOUN
fnp-3766	65	43	0n3r	0n3r	NOUN
fnp-3766	65	44	human	human	ADJ
fnp-3766	65	45	tau	tau	PROPN
fnp-3766	65	46	and	and	CCONJ
fnp-3766	65	47	also	also	ADV
fnp-3766	65	48	reacts	react	VERB
fnp-3766	65	49	with	with	ADP
fnp-3766	65	50	0n4r	0n4r	NOUN
fnp-3766	65	51	human	human	PROPN
fnp-3766	65	52	tau	tau	PROPN
fnp-3766	65	53	(	(	PUNCT
fnp-3766	65	54	39	39	NUM
fnp-3766	65	55	,	,	PUNCT
fnp-3766	65	56	40	40	NUM
fnp-3766	65	57	)	)	PUNCT
fnp-3766	65	58	)	)	PUNCT
fnp-3766	65	59	,	,	PUNCT
fnp-3766	65	60	and	and	CCONJ
fnp-3766	65	61	anti	anti	ADJ
fnp-3766	65	62	-	-	ADJ
fnp-3766	65	63	β	β	NOUN
fnp-3766	65	64	-	-	NOUN
fnp-3766	65	65	actin	actin	NOUN
fnp-3766	65	66	(	(	PUNCT
fnp-3766	65	67	sigma	sigma	PROPN
fnp-3766	65	68	-	-	PUNCT
fnp-3766	65	69	aldrich	aldrich	PROPN
fnp-3766	65	70	,	,	PUNCT
fnp-3766	65	71	st	st	PROPN
fnp-3766	65	72	.	.	PROPN
fnp-3766	65	73	louis	louis	PROPN
fnp-3766	65	74	,	,	PUNCT
fnp-3766	65	75	mo	mo	NOUN
fnp-3766	65	76	)	)	PUNCT
fnp-3766	65	77	before	before	ADP
fnp-3766	65	78	incubation	incubation	NOUN
fnp-3766	65	79	with	with	ADP
fnp-3766	65	80	secondary	secondary	ADJ
fnp-3766	65	81	antibody	antibody	NOUN
fnp-3766	65	82	,	,	PUNCT
fnp-3766	65	83	fluorophore	fluorophore	NOUN
fnp-3766	65	84	conjugated	conjugate	VERB
fnp-3766	65	85	alexafluor	alexafluor	NOUN
fnp-3766	65	86	680	680	NUM
fnp-3766	65	87	anti	anti	ADJ
fnp-3766	65	88	-	-	ADJ
fnp-3766	65	89	mouse	mouse	ADJ
fnp-3766	65	90	igg	igg	PROPN
fnp-3766	65	91	(	(	PUNCT
fnp-3766	65	92	thermo	thermo	PROPN
fnp-3766	65	93	fisher	fisher	PROPN
fnp-3766	65	94	scientific	scientific	PROPN
fnp-3766	65	95	,	,	PUNCT
fnp-3766	65	96	waltham	waltham	PROPN
fnp-3766	65	97	,	,	PUNCT
fnp-3766	65	98	ma	ma	PROPN
fnp-3766	65	99	)	)	PUNCT
fnp-3766	65	100	.	.	PUNCT
fnp-3766	66	1	protein	protein	NOUN
fnp-3766	66	2	bands	band	NOUN
fnp-3766	66	3	were	be	AUX
fnp-3766	66	4	detected	detect	VERB
fnp-3766	66	5	and	and	CCONJ
fnp-3766	66	6	quantified	quantify	VERB
fnp-3766	66	7	using	use	VERB
fnp-3766	66	8	the	the	DET
fnp-3766	66	9	multiplex	multiplex	PROPN
fnp-3766	66	10	odyssey	odyssey	PROPN
fnp-3766	66	11	infrared	infrared	ADJ
fnp-3766	66	12	imaging	imaging	NOUN
fnp-3766	66	13	system	system	NOUN
fnp-3766	66	14	(	(	PUNCT
fnp-3766	66	15	bio	bio	NOUN
fnp-3766	66	16	-	-	ADJ
fnp-3766	66	17	rad	rad	PROPN
fnp-3766	66	18	,	,	PUNCT
fnp-3766	66	19	hercules	hercule	NOUN
fnp-3766	66	20	,	,	PUNCT
fnp-3766	66	21	ca	ca	NOUN
fnp-3766	66	22	)	)	PUNCT
fnp-3766	66	23	.	.	PUNCT
fnp-3766	67	1	table	table	NOUN
fnp-3766	67	2	2	2	NUM
fnp-3766	67	3	.	.	X
fnp-3766	68	1	mouse	mouse	NOUN
fnp-3766	68	2	strains	strain	NOUN
fnp-3766	68	3	used	use	VERB
fnp-3766	68	4	in	in	ADP
fnp-3766	68	5	this	this	DET
fnp-3766	68	6	study	study	NOUN
fnp-3766	68	7	.	.	PUNCT
fnp-3766	69	1	caa	caa	NOUN
fnp-3766	69	2	,	,	PUNCT
fnp-3766	69	3	cerebral	cerebral	ADJ
fnp-3766	69	4	amyloid	amyloid	NOUN
fnp-3766	69	5	angiopathy	angiopathy	NOUN
fnp-3766	69	6	;	;	PUNCT
fnp-3766	69	7	na	na	PART
fnp-3766	69	8	,	,	PUNCT
fnp-3766	69	9	not	not	PART
fnp-3766	69	10	applicable	applicable	ADJ
fnp-3766	69	11	.	.	PUNCT
fnp-3766	70	1	the	the	DET
fnp-3766	70	2	m20	m20	PROPN
fnp-3766	70	3	mice	mouse	NOUN
fnp-3766	70	4	express	express	VERB
fnp-3766	70	5	wild	wild	ADJ
fnp-3766	70	6	type	type	NOUN
fnp-3766	70	7	αsyn	αsyn	NOUN
fnp-3766	70	8	under	under	ADP
fnp-3766	70	9	the	the	DET
fnp-3766	70	10	control	control	NOUN
fnp-3766	70	11	of	of	ADP
fnp-3766	70	12	the	the	DET
fnp-3766	70	13	prion	prion	NOUN
fnp-3766	70	14	promoter	promoter	NOUN
fnp-3766	70	15	and	and	CCONJ
fnp-3766	70	16	do	do	AUX
fnp-3766	70	17	not	not	PART
fnp-3766	70	18	develop	develop	VERB
fnp-3766	70	19	αsyn	αsyn	ADJ
fnp-3766	70	20	pathology	pathology	NOUN
fnp-3766	70	21	(	(	PUNCT
fnp-3766	70	22	41	41	NUM
fnp-3766	70	23	)	)	PUNCT
fnp-3766	70	24	.	.	PUNCT
fnp-3766	71	1	prp.huaβ/ps1	prp.huaβ/ps1	NOUN
fnp-3766	71	2	mice	mouse	NOUN
fnp-3766	71	3	express	express	VERB
fnp-3766	71	4	human	human	ADJ
fnp-3766	71	5	appswe	appswe	NOUN
fnp-3766	71	6	and	and	CCONJ
fnp-3766	71	7	human	human	PROPN
fnp-3766	71	8	ps1de9	ps1de9	PROPN
fnp-3766	71	9	.	.	PUNCT
fnp-3766	72	1	prp.moaβ/ps1	prp.moaβ/ps1	PROPN
fnp-3766	72	2	mice	mouse	NOUN
fnp-3766	72	3	express	express	VERB
fnp-3766	72	4	mouse	mouse	PROPN
fnp-3766	72	5	appswe	appswe	NOUN
fnp-3766	72	6	mutation	mutation	NOUN
fnp-3766	72	7	and	and	CCONJ
fnp-3766	72	8	human	human	NOUN
fnp-3766	72	9	ps1de9	ps1de9	PROPN
fnp-3766	72	10	,	,	PUNCT
fnp-3766	72	11	and	and	CCONJ
fnp-3766	72	12	tet.moaβ	tet.moaβ	NUM
fnp-3766	72	13	mice	mice	NOUN
fnp-3766	72	14	expresses	express	VERB
fnp-3766	72	15	inducible	inducible	ADJ
fnp-3766	72	16	mouse	mouse	NOUN
fnp-3766	72	17	appswe	appswe	NOUN
fnp-3766	72	18	(	(	PUNCT
fnp-3766	72	19	37	37	NUM
fnp-3766	72	20	)	)	PUNCT
fnp-3766	72	21	.	.	PUNCT
fnp-3766	73	1	these	these	DET
fnp-3766	73	2	mice	mouse	NOUN
fnp-3766	73	3	were	be	AUX
fnp-3766	73	4	bred	breed	VERB
fnp-3766	73	5	in	in	ADP
fnp-3766	73	6	-	-	PUNCT
fnp-3766	73	7	house	house	NOUN
fnp-3766	73	8	.	.	PUNCT
fnp-3766	74	1	prp.appsi	prp.appsi	PROPN
fnp-3766	74	2	and	and	CCONJ
fnp-3766	74	3	m20	m20	PROPN
fnp-3766	74	4	were	be	AUX
fnp-3766	74	5	maintained	maintain	VERB
fnp-3766	74	6	on	on	ADP
fnp-3766	74	7	hybrid	hybrid	ADJ
fnp-3766	74	8	c57bl6	c57bl6	NOUN
fnp-3766	74	9	/	/	SYM
fnp-3766	74	10	c3h	c3h	PROPN
fnp-3766	74	11	backgrounds	background	NOUN
fnp-3766	74	12	,	,	PUNCT
fnp-3766	74	13	following	follow	VERB
fnp-3766	74	14	a	a	DET
fnp-3766	74	15	breeding	breeding	NOUN
fnp-3766	74	16	scheme	scheme	NOUN
fnp-3766	74	17	in	in	ADP
fnp-3766	74	18	which	which	PRON
fnp-3766	74	19	transgene	transgene	NOUN
fnp-3766	74	20	-	-	PUNCT
fnp-3766	74	21	positive	positive	ADJ
fnp-3766	74	22	males	male	NOUN
fnp-3766	74	23	were	be	AUX
fnp-3766	74	24	bred	breed	VERB
fnp-3766	74	25	to	to	ADP
fnp-3766	74	26	nontransgenic	nontransgenic	ADJ
fnp-3766	74	27	f1	f1	PROPN
fnp-3766	74	28	b6	b6	NOUN
fnp-3766	74	29	/	/	SYM
fnp-3766	74	30	c3	c3	NOUN
fnp-3766	74	31	female	female	ADJ
fnp-3766	74	32	mice	mouse	NOUN
fnp-3766	74	33	.	.	PUNCT
fnp-3766	75	1	the	the	DET
fnp-3766	75	2	itau	itau	NOUN
fnp-3766	75	3	-	-	PUNCT
fnp-3766	75	4	p301l	p301l	NOUN
fnp-3766	75	5	mice	mouse	NOUN
fnp-3766	75	6	we	we	PRON
fnp-3766	75	7	used	use	VERB
fnp-3766	75	8	had	have	AUX
fnp-3766	75	9	been	be	AUX
fnp-3766	75	10	backcrossed	backcross	VERB
fnp-3766	75	11	to	to	ADP
fnp-3766	75	12	the	the	DET
fnp-3766	75	13	fvb	fvb	PROPN
fnp-3766	75	14	/	/	SYM
fnp-3766	75	15	ncr	ncr	PROPN
fnp-3766	75	16	mouse	mouse	NOUN
fnp-3766	75	17	strain	strain	NOUN
fnp-3766	75	18	for	for	ADP
fnp-3766	75	19	more	more	ADJ
fnp-3766	75	20	than	than	ADP
fnp-3766	75	21	10	10	NUM
fnp-3766	75	22	generations	generation	NOUN
fnp-3766	75	23	.	.	PUNCT
fnp-3766	76	1	appsi	appsi	PROPN
fnp-3766	76	2	/	/	SYM
fnp-3766	76	3	tau	tau	PROPN
fnp-3766	76	4	-	-	PUNCT
fnp-3766	76	5	p301l	p301l	PROPN
fnp-3766	76	6	and	and	CCONJ
fnp-3766	76	7	appsi	appsi	PROPN
fnp-3766	76	8	/	/	SYM
fnp-3766	76	9	αsyn	αsyn	NOUN
fnp-3766	76	10	mice	mouse	NOUN
fnp-3766	76	11	were	be	AUX
fnp-3766	76	12	generated	generate	VERB
fnp-3766	76	13	by	by	ADP
fnp-3766	76	14	intercrossing	intercrosse	VERB
fnp-3766	76	15	mice	mouse	NOUN
fnp-3766	76	16	that	that	SCONJ
fnp-3766	76	17	where	where	SCONJ
fnp-3766	76	18	hemizygous	hemizygous	ADJ
fnp-3766	76	19	for	for	ADP
fnp-3766	76	20	the	the	DET
fnp-3766	76	21	respective	respective	ADJ
fnp-3766	76	22	transgenes	transgene	NOUN
fnp-3766	76	23	.	.	PUNCT
fnp-3766	77	1	prp.appsi	prp.appsi	PROPN
fnp-3766	77	2	mice	mouse	NOUN
fnp-3766	77	3	were	be	AUX
fnp-3766	77	4	genotyped	genotype	VERB
fnp-3766	77	5	by	by	ADP
fnp-3766	77	6	visualizing	visualize	VERB
fnp-3766	77	7	gfp	gfp	PROPN
fnp-3766	77	8	expression	expression	NOUN
fnp-3766	77	9	,	,	PUNCT
fnp-3766	77	10	which	which	PRON
fnp-3766	77	11	is	be	AUX
fnp-3766	77	12	possible	possible	ADJ
fnp-3766	77	13	because	because	SCONJ
fnp-3766	77	14	these	these	DET
fnp-3766	77	15	mice	mouse	NOUN
fnp-3766	77	16	were	be	AUX
fnp-3766	77	17	co	co	VERB
fnp-3766	77	18	-	-	VERB
fnp-3766	77	19	injected	inject	VERB
fnp-3766	77	20	with	with	ADP
fnp-3766	77	21	a	a	DET
fnp-3766	77	22	transgene	transgene	NOUN
fnp-3766	77	23	that	that	PRON
fnp-3766	77	24	expresses	express	VERB
fnp-3766	77	25	gfp	gfp	PROPN
fnp-3766	77	26	in	in	ADP
fnp-3766	77	27	the	the	DET
fnp-3766	77	28	skin	skin	NOUN
fnp-3766	77	29	integrated	integrate	VERB
fnp-3766	77	30	next	next	ADV
fnp-3766	77	31	to	to	ADP
fnp-3766	77	32	app	app	NOUN
fnp-3766	77	33	transgene	transgene	NOUN
fnp-3766	77	34	.	.	PUNCT
fnp-3766	78	1	prp.appsi/itau-p301l	prp.appsi/itau-p301l	NOUN
fnp-3766	78	2	mice	mouse	NOUN
fnp-3766	78	3	were	be	AUX
fnp-3766	78	4	genotyped	genotype	VERB
fnp-3766	78	5	for	for	ADP
fnp-3766	78	6	app	app	NOUN
fnp-3766	78	7	by	by	ADP
fnp-3766	78	8	illumination	illumination	NOUN
fnp-3766	78	9	and	and	CCONJ
fnp-3766	78	10	visualization	visualization	NOUN
fnp-3766	78	11	with	with	ADP
fnp-3766	78	12	special	special	ADJ
fnp-3766	78	13	filter	filter	NOUN
fnp-3766	78	14	goggles	goggle	NOUN
fnp-3766	78	15	(	(	PUNCT
fnp-3766	78	16	bls	bls	PROPN
fnp-3766	78	17	ltd	ltd	PROPN
fnp-3766	78	18	,	,	PUNCT
fnp-3766	78	19	budapest	budapest	PROPN
fnp-3766	78	20	,	,	PUNCT
fnp-3766	78	21	hungary	hungary	PROPN
fnp-3766	78	22	)	)	PUNCT
fnp-3766	78	23	and	and	CCONJ
fnp-3766	78	24	for	for	ADP
fnp-3766	78	25	tau	tau	PROPN
fnp-3766	78	26	by	by	ADP
fnp-3766	78	27	pcr	pcr	PROPN
fnp-3766	78	28	of	of	ADP
fnp-3766	78	29	tail	tail	NOUN
fnp-3766	78	30	dna	dna	PROPN
fnp-3766	78	31	.	.	PUNCT
fnp-3766	79	1	itau	itau	PROPN
fnp-3766	79	2	-	-	PUNCT
fnp-3766	79	3	p301l	p301l	NOUN
fnp-3766	79	4	and	and	CCONJ
fnp-3766	79	5	m20	m20	PROPN
fnp-3766	79	6	mice	mouse	NOUN
fnp-3766	79	7	were	be	AUX
fnp-3766	79	8	genotyped	genotype	VERB
fnp-3766	79	9	by	by	ADP
fnp-3766	79	10	pcr	pcr	NOUN
fnp-3766	79	11	of	of	ADP
fnp-3766	79	12	tail	tail	NOUN
fnp-3766	79	13	dna	dna	PROPN
fnp-3766	79	14	.	.	PUNCT
fnp-3766	80	1	prp.appsi	prp.appsi	PROPN
fnp-3766	80	2	mice	mouse	NOUN
fnp-3766	80	3	destined	destine	VERB
fnp-3766	80	4	for	for	ADP
fnp-3766	80	5	behavioral	behavioral	ADJ
fnp-3766	80	6	studies	study	NOUN
fnp-3766	80	7	were	be	AUX
fnp-3766	80	8	backcrossed	backcross	VERB
fnp-3766	80	9	one	one	NUM
fnp-3766	80	10	generation	generation	NOUN
fnp-3766	80	11	onto	onto	ADP
fnp-3766	80	12	c57bl6	c57bl6	NOUN
fnp-3766	80	13	.	.	PUNCT
fnp-3766	81	1	all	all	DET
fnp-3766	81	2	animals	animal	NOUN
fnp-3766	81	3	were	be	AUX
fnp-3766	81	4	housed	house	VERB
fnp-3766	81	5	1	1	NUM
fnp-3766	81	6	-	-	SYM
fnp-3766	81	7	5	5	NUM
fnp-3766	81	8	per	per	ADP
fnp-3766	81	9	cage	cage	NOUN
fnp-3766	81	10	with	with	ADP
fnp-3766	81	11	unlimited	unlimited	ADJ
fnp-3766	81	12	access	access	NOUN
fnp-3766	81	13	to	to	ADP
fnp-3766	81	14	food	food	NOUN
fnp-3766	81	15	and	and	CCONJ
fnp-3766	81	16	water	water	NOUN
fnp-3766	81	17	with	with	ADP
fnp-3766	81	18	a	a	DET
fnp-3766	81	19	14	14	NUM
fnp-3766	81	20	-	-	PUNCT
fnp-3766	81	21	hour	hour	NOUN
fnp-3766	81	22	light	light	NOUN
fnp-3766	81	23	and	and	CCONJ
fnp-3766	81	24	10	10	NUM
fnp-3766	81	25	-	-	PUNCT
fnp-3766	81	26	hour	hour	NOUN
fnp-3766	81	27	dark	dark	ADJ
fnp-3766	81	28	cycle	cycle	NOUN
fnp-3766	81	29	.	.	PUNCT
fnp-3766	82	1	all	all	DET
fnp-3766	82	2	experiments	experiment	NOUN
fnp-3766	82	3	involving	involve	VERB
fnp-3766	82	4	mice	mouse	NOUN
fnp-3766	82	5	were	be	AUX
fnp-3766	82	6	approved	approve	VERB
fnp-3766	82	7	by	by	ADP
fnp-3766	82	8	the	the	DET
fnp-3766	82	9	university	university	PROPN
fnp-3766	82	10	of	of	ADP
fnp-3766	82	11	florida	florida	PROPN
fnp-3766	82	12	institutional	institutional	PROPN
fnp-3766	82	13	animal	animal	NOUN
fnp-3766	82	14	care	care	NOUN
fnp-3766	82	15	and	and	CCONJ
fnp-3766	82	16	use	use	VERB
fnp-3766	82	17	committee	committee	NOUN
fnp-3766	82	18	(	(	PUNCT
fnp-3766	82	19	iacuc	iacuc	NOUN
fnp-3766	82	20	)	)	PUNCT
fnp-3766	82	21	and	and	CCONJ
fnp-3766	82	22	conducted	conduct	VERB
fnp-3766	82	23	in	in	ADP
fnp-3766	82	24	accordance	accordance	NOUN
fnp-3766	82	25	with	with	ADP
fnp-3766	82	26	nih	nih	PROPN
fnp-3766	82	27	guidelines	guideline	NOUN
fnp-3766	82	28	.	.	PUNCT
fnp-3766	83	1	human	human	ADJ
fnp-3766	83	2	brain	brain	NOUN
fnp-3766	83	3	lysates	lysate	NOUN
fnp-3766	83	4	human	human	ADJ
fnp-3766	83	5	and	and	CCONJ
fnp-3766	83	6	mouse	mouse	NOUN
fnp-3766	83	7	brain	brain	NOUN
fnp-3766	83	8	lysates	lysate	NOUN
fnp-3766	83	9	were	be	AUX
fnp-3766	83	10	prepared	prepare	VERB
fnp-3766	83	11	as	as	ADP
fnp-3766	83	12	previously	previously	ADV
fnp-3766	83	13	described	describe	VERB
fnp-3766	83	14	(	(	PUNCT
fnp-3766	83	15	42	42	NUM
fnp-3766	83	16	)	)	PUNCT
fnp-3766	83	17	.	.	PUNCT
fnp-3766	84	1	briefly	briefly	NOUN
fnp-3766	84	2	,	,	PUNCT
fnp-3766	84	3	frozen	frozen	ADJ
fnp-3766	84	4	tissue	tissue	NOUN
fnp-3766	84	5	was	be	AUX
fnp-3766	84	6	homogenized	homogenize	VERB
fnp-3766	84	7	at	at	ADP
fnp-3766	84	8	10	10	NUM
fnp-3766	84	9	%	%	NOUN
fnp-3766	84	10	(	(	PUNCT
fnp-3766	84	11	w	w	NOUN
fnp-3766	84	12	/	/	SYM
fnp-3766	84	13	v	v	NOUN
fnp-3766	84	14	)	)	PUNCT
fnp-3766	84	15	in	in	ADP
fnp-3766	84	16	sterile	sterile	ADJ
fnp-3766	84	17	pbs	pbs	PROPN
fnp-3766	84	18	,	,	PUNCT
fnp-3766	84	19	subjected	subject	VERB
fnp-3766	84	20	to	to	ADP
fnp-3766	84	21	vortex	vortex	NOUN
fnp-3766	84	22	and	and	CCONJ
fnp-3766	84	23	sonication	sonication	NOUN
fnp-3766	84	24	(	(	PUNCT
fnp-3766	84	25	3	3	NUM
fnp-3766	84	26	x	x	SYM
fnp-3766	84	27	5	5	NUM
fnp-3766	84	28	sec	sec	PROPN
fnp-3766	84	29	)	)	PUNCT
fnp-3766	84	30	and	and	CCONJ
fnp-3766	84	31	then	then	ADV
fnp-3766	84	32	centrifuged	centrifuge	VERB
fnp-3766	84	33	3000	3000	NUM
fnp-3766	84	34	x	x	SYM
fnp-3766	84	35	g	g	NOUN
fnp-3766	84	36	for	for	ADP
fnp-3766	84	37	5	5	NUM
fnp-3766	84	38	min	min	NOUN
fnp-3766	84	39	at	at	ADP
fnp-3766	84	40	4	4	NUM
fnp-3766	84	41	°	°	NOUN
fnp-3766	84	42	c	c	NOUN
fnp-3766	84	43	.	.	PUNCT
fnp-3766	85	1	lysates	lysate	NOUN
fnp-3766	85	2	were	be	AUX
fnp-3766	85	3	immediately	immediately	ADV
fnp-3766	85	4	aliquoted	aliquote	VERB
fnp-3766	85	5	and	and	CCONJ
fnp-3766	85	6	stored	store	VERB
fnp-3766	85	7	at	at	ADP
fnp-3766	85	8	-80	-80	NOUN
fnp-3766	85	9	°	°	NOUN
fnp-3766	85	10	c	c	NOUN
fnp-3766	85	11	until	until	SCONJ
fnp-3766	85	12	needed	need	VERB
fnp-3766	85	13	.	.	PUNCT
fnp-3766	86	1	as	as	SCONJ
fnp-3766	86	2	previously	previously	ADV
fnp-3766	86	3	described	describe	VERB
fnp-3766	86	4	(	(	PUNCT
fnp-3766	86	5	25	25	NUM
fnp-3766	86	6	)	)	PUNCT
fnp-3766	86	7	,	,	PUNCT
fnp-3766	86	8	the	the	DET
fnp-3766	86	9	aβ	aβ	PROPN
fnp-3766	86	10	levels	level	NOUN
fnp-3766	86	11	and	and	CCONJ
fnp-3766	86	12	solubility	solubility	NOUN
fnp-3766	86	13	in	in	ADP
fnp-3766	86	14	the	the	DET
fnp-3766	86	15	lysates	lysate	NOUN
fnp-3766	86	16	was	be	AUX
fnp-3766	86	17	assessed	assess	VERB
fnp-3766	86	18	by	by	ADP
fnp-3766	86	19	western	western	ADJ
fnp-3766	86	20	blotting	blotting	NOUN
fnp-3766	86	21	.	.	PUNCT
fnp-3766	87	1	briefly	briefly	NOUN
fnp-3766	87	2	,	,	PUNCT
fnp-3766	87	3	lysates	lysate	NOUN
fnp-3766	87	4	were	be	AUX
fnp-3766	87	5	heated	heat	VERB
fnp-3766	87	6	at	at	ADP
fnp-3766	87	7	50	50	NUM
fnp-3766	87	8	°	°	ADP
fnp-3766	87	9	c	c	NOUN
fnp-3766	87	10	for	for	ADP
fnp-3766	87	11	three	three	NUM
fnp-3766	87	12	minutes	minute	NOUN
fnp-3766	87	13	in	in	ADP
fnp-3766	87	14	the	the	DET
fnp-3766	87	15	presence	presence	NOUN
fnp-3766	87	16	of	of	ADP
fnp-3766	87	17	denaturing	denature	VERB
fnp-3766	87	18	sample	sample	NOUN
fnp-3766	87	19	buffer	buffer	NOUN
fnp-3766	87	20	,	,	PUNCT
fnp-3766	87	21	were	be	AUX
fnp-3766	87	22	separated	separate	VERB
fnp-3766	87	23	on	on	ADP
fnp-3766	87	24	a	a	DET
fnp-3766	87	25	4	4	NUM
fnp-3766	87	26	-	-	SYM
fnp-3766	87	27	12	12	NUM
fnp-3766	87	28	%	%	NOUN
fnp-3766	87	29	bis	bis	ADJ
fnp-3766	87	30	-	-	ADJ
fnp-3766	87	31	tris	tris	ADJ
fnp-3766	87	32	gel	gel	NOUN
fnp-3766	87	33	(	(	PUNCT
fnp-3766	87	34	bio	bio	NOUN
fnp-3766	87	35	-	-	PUNCT
fnp-3766	87	36	rad	rad	PROPN
fnp-3766	87	37	,	,	PUNCT
fnp-3766	87	38	hercules	hercule	NOUN
fnp-3766	87	39	,	,	PUNCT
fnp-3766	87	40	ca	ca	NOUN
fnp-3766	87	41	)	)	PUNCT
fnp-3766	87	42	in	in	ADP
fnp-3766	87	43	1x2-(n	1x2-(n	ADJ
fnp-3766	87	44	-	-	PUNCT
fnp-3766	87	45	morpholino)ethanesulfonic	morpholino)ethanesulfonic	ADJ
fnp-3766	87	46	acid	acid	NOUN
fnp-3766	87	47	(	(	PUNCT
fnp-3766	87	48	mes	me	NOUN
fnp-3766	87	49	)	)	PUNCT
fnp-3766	87	50	running	running	NOUN
fnp-3766	87	51	buffer	buffer	NOUN
fnp-3766	87	52	(	(	PUNCT
fnp-3766	87	53	bio	bio	NOUN
fnp-3766	87	54	-	-	ADJ
fnp-3766	87	55	rad	rad	PROPN
fnp-3766	87	56	,	,	PUNCT
fnp-3766	87	57	hercules	hercule	NOUN
fnp-3766	87	58	,	,	PUNCT
fnp-3766	87	59	ca	ca	NOUN
fnp-3766	87	60	)	)	PUNCT
fnp-3766	87	61	and	and	CCONJ
fnp-3766	87	62	transferred	transfer	VERB
fnp-3766	87	63	onto	onto	ADP
fnp-3766	87	64	nitrocellulose	nitrocellulose	NOUN
fnp-3766	87	65	membrane	membrane	NOUN
fnp-3766	87	66	(	(	PUNCT
fnp-3766	87	67	bio	bio	NOUN
fnp-3766	87	68	-	-	ADJ
fnp-3766	87	69	rad	rad	PROPN
fnp-3766	87	70	,	,	PUNCT
fnp-3766	87	71	hercules	hercule	NOUN
fnp-3766	87	72	,	,	PUNCT
fnp-3766	87	73	ca	ca	NOUN
fnp-3766	87	74	)	)	PUNCT
fnp-3766	87	75	.	.	PUNCT
fnp-3766	88	1	the	the	DET
fnp-3766	88	2	membrane	membrane	NOUN
fnp-3766	88	3	was	be	AUX
fnp-3766	88	4	boiled	boil	VERB
fnp-3766	88	5	in	in	ADP
fnp-3766	88	6	pbs	pbs	PROPN
fnp-3766	88	7	for	for	ADP
fnp-3766	88	8	5	5	NUM
fnp-3766	88	9	min	min	NOUN
fnp-3766	88	10	,	,	PUNCT
fnp-3766	88	11	blocked	block	VERB
fnp-3766	88	12	in	in	ADP
fnp-3766	88	13	starting	start	VERB
fnp-3766	88	14	block	block	NOUN
fnp-3766	88	15	(	(	PUNCT
fnp-3766	88	16	thermo	thermo	NOUN
fnp-3766	88	17	fisher	fisher	PROPN
fnp-3766	88	18	scientific	scientific	ADJ
fnp-3766	88	19	[	[	X
fnp-3766	88	20	formerly	formerly	ADV
fnp-3766	88	21	thermo	thermo	NOUN
fnp-3766	88	22	scientific	scientific	NOUN
fnp-3766	88	23	]	]	PUNCT
fnp-3766	88	24	,	,	PUNCT
fnp-3766	88	25	waltham	waltham	PROPN
fnp-3766	88	26	,	,	PUNCT
fnp-3766	88	27	ma	ma	PROPN
fnp-3766	88	28	)	)	PUNCT
fnp-3766	88	29	and	and	CCONJ
fnp-3766	88	30	incubated	incubate	VERB
fnp-3766	88	31	overnight	overnight	ADV
fnp-3766	88	32	at	at	ADP
fnp-3766	88	33	4	4	NUM
fnp-3766	88	34	°	°	ADP
fnp-3766	88	35	c	c	NOUN
fnp-3766	88	36	with	with	ADP
fnp-3766	88	37	primary	primary	ADJ
fnp-3766	88	38	antibody	antibody	NOUN
fnp-3766	88	39	ab5	ab5	NOUN
fnp-3766	88	40	(	(	PUNCT
fnp-3766	88	41	human	human	ADJ
fnp-3766	88	42	aβ1	aβ1	NOUN
fnp-3766	88	43	-	-	PUNCT
fnp-3766	88	44	16	16	NUM
fnp-3766	88	45	specific	specific	ADJ
fnp-3766	88	46	;	;	PUNCT
fnp-3766	88	47	t.e	t.e	PROPN
fnp-3766	88	48	.	.	PROPN
fnp-3766	88	49	golde	golde	PROPN
fnp-3766	88	50	)	)	PUNCT
fnp-3766	88	51	before	before	ADP
fnp-3766	88	52	incubation	incubation	NOUN
fnp-3766	88	53	with	with	ADP
fnp-3766	88	54	the	the	DET
fnp-3766	88	55	secondary	secondary	ADJ
fnp-3766	88	56	antibody	antibody	NOUN
fnp-3766	88	57	,	,	PUNCT
fnp-3766	88	58	fluorophore	fluorophore	NOUN
fnp-3766	88	59	conjugated	conjugate	VERB
fnp-3766	88	60	alexa	alexa	NOUN
fnp-3766	88	61	fluor	fluor	NOUN
fnp-3766	88	62	680	680	NUM
fnp-3766	88	63	anti	anti	ADJ
fnp-3766	88	64	-	-	ADJ
fnp-3766	88	65	mouse	mouse	ADJ
fnp-3766	88	66	igg	igg	PROPN
fnp-3766	88	67	(	(	PUNCT
fnp-3766	88	68	thermo	thermo	PROPN
fnp-3766	88	69	fisher	fisher	PROPN
fnp-3766	88	70	scientific	scientific	PROPN
fnp-3766	88	71	,	,	PUNCT
fnp-3766	88	72	waltham	waltham	PROPN
fnp-3766	88	73	,	,	PUNCT
fnp-3766	88	74	ma	ma	PROPN
fnp-3766	88	75	)	)	PUNCT
fnp-3766	88	76	.	.	PUNCT
fnp-3766	89	1	protein	protein	NOUN
fnp-3766	89	2	bands	band	NOUN
fnp-3766	89	3	were	be	AUX
fnp-3766	89	4	detected	detect	VERB
fnp-3766	89	5	using	use	VERB
fnp-3766	89	6	the	the	DET
fnp-3766	89	7	multiplex	multiplex	PROPN
fnp-3766	89	8	odyssey	odyssey	PROPN
fnp-3766	89	9	infrared	infrared	ADJ
fnp-3766	89	10	imaging	imaging	NOUN
fnp-3766	89	11	system	system	NOUN
fnp-3766	89	12	(	(	PUNCT
fnp-3766	89	13	bio	bio	NOUN
fnp-3766	89	14	-	-	ADJ
fnp-3766	89	15	rad	rad	PROPN
fnp-3766	89	16	,	,	PUNCT
fnp-3766	89	17	hercules	hercule	NOUN
fnp-3766	89	18	,	,	PUNCT
fnp-3766	89	19	ca	ca	NOUN
fnp-3766	89	20	)	)	PUNCT
fnp-3766	89	21	.	.	PUNCT
fnp-3766	90	1	brain	brain	NOUN
fnp-3766	90	2	seeding	seed	VERB
fnp-3766	90	3	with	with	ADP
fnp-3766	90	4	neonatal	neonatal	ADJ
fnp-3766	90	5	cerebral	cerebral	ADJ
fnp-3766	90	6	ventricle	ventricle	NOUN
fnp-3766	90	7	injections	injection	NOUN
fnp-3766	90	8	injections	injection	NOUN
fnp-3766	90	9	of	of	ADP
fnp-3766	90	10	human	human	ADJ
fnp-3766	90	11	brain	brain	NOUN
fnp-3766	90	12	lysates	lysate	NOUN
fnp-3766	90	13	and	and	CCONJ
fnp-3766	90	14	lysates	lysate	NOUN
fnp-3766	90	15	from	from	ADP
fnp-3766	90	16	a	a	DET
fnp-3766	90	17	27mo	27mo	NOUN
fnp-3766	90	18	prp.appsi	prp.appsi	NOUN
fnp-3766	90	19	mouse	mouse	NOUN
fnp-3766	90	20	,	,	PUNCT
fnp-3766	90	21	a	a	DET
fnp-3766	90	22	25mo	25mo	ADJ
fnp-3766	90	23	prp.huaβ/ps1	prp.huaβ/ps1	NOUN
fnp-3766	90	24	mouse	mouse	NOUN
fnp-3766	90	25	,	,	PUNCT
fnp-3766	90	26	a	a	DET
fnp-3766	90	27	24mo	24mo	ADJ
fnp-3766	90	28	tet.moaβ	tet.moaβ	PRON
fnp-3766	90	29	mouse	mouse	NOUN
fnp-3766	90	30	,	,	PUNCT
fnp-3766	90	31	and	and	CCONJ
fnp-3766	90	32	a	a	DET
fnp-3766	90	33	24mo	24mo	ADJ
fnp-3766	90	34	prp.moaβ/ps1	prp.moaβ/ps1	PROPN
fnp-3766	90	35	mouse	mouse	NOUN
fnp-3766	90	36	were	be	AUX
fnp-3766	90	37	performed	perform	VERB
fnp-3766	90	38	as	as	SCONJ
fnp-3766	90	39	described	describe	VERB
fnp-3766	90	40	previously	previously	ADV
fnp-3766	90	41	with	with	ADP
fnp-3766	90	42	recombinant	recombinant	ADJ
fnp-3766	90	43	adeno	adeno	NOUN
fnp-3766	90	44	-	-	PUNCT
fnp-3766	90	45	associated	associate	VERB
fnp-3766	90	46	virus	virus	NOUN
fnp-3766	90	47	(	(	PUNCT
fnp-3766	90	48	43	43	NUM
fnp-3766	90	49	)	)	PUNCT
fnp-3766	90	50	.	.	PUNCT
fnp-3766	91	1	briefly	briefly	NOUN
fnp-3766	91	2	,	,	PUNCT
fnp-3766	91	3	p0	p0	NOUN
fnp-3766	91	4	pups	pup	NOUN
fnp-3766	91	5	were	be	AUX
fnp-3766	91	6	cryoanesthetized	cryoanesthetize	VERB
fnp-3766	91	7	and	and	CCONJ
fnp-3766	91	8	2	2	NUM
fnp-3766	91	9	ul	ul	NOUN
fnp-3766	91	10	of	of	ADP
fnp-3766	91	11	human	human	ADJ
fnp-3766	91	12	or	or	CCONJ
fnp-3766	91	13	mouse	mouse	NOUN
fnp-3766	91	14	brain	brain	NOUN
fnp-3766	91	15	lysates	lysate	NOUN
fnp-3766	91	16	were	be	AUX
fnp-3766	91	17	bilaterally	bilaterally	ADV
fnp-3766	91	18	injected	inject	VERB
fnp-3766	91	19	into	into	ADP
fnp-3766	91	20	the	the	DET
fnp-3766	91	21	cerebral	cerebral	ADJ
fnp-3766	91	22	ventricle	ventricle	NOUN
fnp-3766	91	23	using	use	VERB
fnp-3766	91	24	a	a	DET
fnp-3766	91	25	10	10	NUM
fnp-3766	91	26	ul	ul	NOUN
fnp-3766	91	27	hamilton	hamilton	PROPN
fnp-3766	91	28	syringe	syringe	PROPN
fnp-3766	91	29	with	with	ADP
fnp-3766	91	30	a	a	DET
fnp-3766	91	31	30	30	NUM
fnp-3766	91	32	-	-	PUNCT
fnp-3766	91	33	inch	inch	NOUN
fnp-3766	91	34	needle	needle	NOUN
fnp-3766	91	35	(	(	PUNCT
fnp-3766	91	36	hamilton	hamilton	PROPN
fnp-3766	91	37	company	company	PROPN
fnp-3766	91	38	,	,	PUNCT
fnp-3766	91	39	reno	reno	PROPN
fnp-3766	91	40	,	,	PUNCT
fnp-3766	91	41	nv	nv	PROPN
fnp-3766	91	42	)	)	PUNCT
fnp-3766	91	43	.	.	PUNCT
fnp-3766	92	1	pups	pup	NOUN
fnp-3766	92	2	were	be	AUX
fnp-3766	92	3	placed	place	VERB
fnp-3766	92	4	on	on	ADP
fnp-3766	92	5	a	a	DET
fnp-3766	92	6	heating	heating	NOUN
fnp-3766	92	7	pad	pad	NOUN
fnp-3766	92	8	for	for	ADP
fnp-3766	92	9	recovery	recovery	NOUN
fnp-3766	92	10	and	and	CCONJ
fnp-3766	92	11	returned	return	VERB
fnp-3766	92	12	to	to	ADP
fnp-3766	92	13	their	their	PRON
fnp-3766	92	14	home	home	NOUN
fnp-3766	92	15	cage	cage	NOUN
fnp-3766	92	16	.	.	PUNCT
fnp-3766	93	1	cohorts	cohort	NOUN
fnp-3766	93	2	of	of	ADP
fnp-3766	93	3	mice	mouse	NOUN
fnp-3766	93	4	were	be	AUX
fnp-3766	93	5	euthanized	euthanize	VERB
fnp-3766	93	6	at	at	ADP
fnp-3766	93	7	6	6	NUM
fnp-3766	93	8	,	,	PUNCT
fnp-3766	93	9	9	9	NUM
fnp-3766	93	10	,	,	PUNCT
fnp-3766	93	11	12	12	NUM
fnp-3766	93	12	,	,	PUNCT
fnp-3766	93	13	and	and	CCONJ
fnp-3766	93	14	18	18	NUM
fnp-3766	93	15	months	month	NOUN
fnp-3766	93	16	for	for	ADP
fnp-3766	93	17	analysis	analysis	NOUN
fnp-3766	93	18	.	.	PUNCT
fnp-3766	94	1	both	both	DET
fnp-3766	94	2	male	male	ADJ
fnp-3766	94	3	and	and	CCONJ
fnp-3766	94	4	female	female	ADJ
fnp-3766	94	5	mice	mouse	NOUN
fnp-3766	94	6	were	be	AUX
fnp-3766	94	7	analyzed	analyze	VERB
fnp-3766	94	8	(	(	PUNCT
fnp-3766	94	9	see	see	VERB
fnp-3766	94	10	tables	table	NOUN
fnp-3766	94	11	s1	s1	NOUN
fnp-3766	94	12	and	and	CCONJ
fnp-3766	94	13	s2	s2	VERB
fnp-3766	94	14	for	for	ADP
fnp-3766	94	15	description	description	NOUN
fnp-3766	94	16	of	of	ADP
fnp-3766	94	17	cohorts	cohort	NOUN
fnp-3766	94	18	)	)	PUNCT
fnp-3766	94	19	.	.	PUNCT
fnp-3766	95	1	mouse	mouse	NOUN
fnp-3766	95	2	brain	brain	NOUN
fnp-3766	95	3	tissue	tissue	NOUN
fnp-3766	95	4	collection	collection	NOUN
fnp-3766	95	5	mice	mouse	NOUN
fnp-3766	95	6	were	be	AUX
fnp-3766	95	7	anesthetized	anesthetize	VERB
fnp-3766	95	8	with	with	ADP
fnp-3766	95	9	isoflurane	isoflurane	NOUN
fnp-3766	95	10	and	and	CCONJ
fnp-3766	95	11	perfused	perfuse	VERB
fnp-3766	95	12	transcardially	transcardially	ADV
fnp-3766	95	13	with	with	ADP
fnp-3766	95	14	20	20	NUM
fnp-3766	95	15	ml	ml	NOUN
fnp-3766	95	16	of	of	ADP
fnp-3766	95	17	cold	cold	PROPN
fnp-3766	95	18	pbs	pbs	PROPN
fnp-3766	95	19	.	.	PUNCT
fnp-3766	96	1	the	the	DET
fnp-3766	96	2	brains	brain	NOUN
fnp-3766	96	3	were	be	AUX
fnp-3766	96	4	cut	cut	VERB
fnp-3766	96	5	sagittally	sagittally	ADV
fnp-3766	96	6	through	through	ADP
fnp-3766	96	7	the	the	DET
fnp-3766	96	8	midline	midline	NOUN
fnp-3766	96	9	,	,	PUNCT
fnp-3766	96	10	and	and	CCONJ
fnp-3766	96	11	one	one	NUM
fnp-3766	96	12	hemibrain	hemibrain	NOUN
fnp-3766	96	13	was	be	AUX
fnp-3766	96	14	drop	drop	NOUN
fnp-3766	96	15	-	-	PUNCT
fnp-3766	96	16	fixed	fix	VERB
fnp-3766	96	17	in	in	ADP
fnp-3766	96	18	4	4	NUM
fnp-3766	96	19	%	%	NOUN
fnp-3766	96	20	paraformaldehyde	paraformaldehyde	NOUN
fnp-3766	96	21	in	in	ADP
fnp-3766	96	22	pbs	pbs	PROPN
fnp-3766	96	23	(	(	PUNCT
fnp-3766	96	24	ph	ph	NOUN
fnp-3766	96	25	7.5	7.5	NUM
fnp-3766	96	26	)	)	PUNCT
fnp-3766	96	27	for	for	ADP
fnp-3766	96	28	~48	~48	NOUN
fnp-3766	96	29	hrs	hrs	NOUN
fnp-3766	96	30	at	at	ADP
fnp-3766	96	31	4	4	NUM
fnp-3766	96	32	°	°	NOUN
fnp-3766	96	33	c	c	NOUN
fnp-3766	96	34	followed	follow	VERB
fnp-3766	96	35	by	by	ADP
fnp-3766	96	36	processing	processing	NOUN
fnp-3766	96	37	and	and	CCONJ
fnp-3766	96	38	paraffin	paraffin	NOUN
fnp-3766	96	39	embedding	embed	VERB
fnp-3766	96	40	.	.	PUNCT
fnp-3766	97	1	the	the	DET
fnp-3766	97	2	other	other	ADJ
fnp-3766	97	3	hemibrain	hemibrain	NOUN
fnp-3766	97	4	was	be	AUX
fnp-3766	97	5	snap	snap	ADJ
fnp-3766	97	6	frozen	freeze	VERB
fnp-3766	97	7	with	with	ADP
fnp-3766	97	8	isopentane	isopentane	NOUN
fnp-3766	97	9	on	on	ADP
fnp-3766	97	10	dry	dry	ADJ
fnp-3766	97	11	-	-	PUNCT
fnp-3766	97	12	ice	ice	NOUN
fnp-3766	97	13	and	and	CCONJ
fnp-3766	97	14	then	then	ADV
fnp-3766	97	15	stored	store	VERB
fnp-3766	97	16	at	at	ADP
fnp-3766	97	17	-80⁰c	-80⁰c	PROPN
fnp-3766	97	18	until	until	SCONJ
fnp-3766	97	19	it	it	PRON
fnp-3766	97	20	was	be	AUX
fnp-3766	97	21	thawed	thaw	VERB
fnp-3766	97	22	and	and	CCONJ
fnp-3766	97	23	homogenized	homogenize	VERB
fnp-3766	97	24	in	in	ADP
fnp-3766	97	25	preparation	preparation	NOUN
fnp-3766	97	26	for	for	ADP
fnp-3766	97	27	elisa	elisa	NOUN
fnp-3766	97	28	measurements	measurement	NOUN
fnp-3766	97	29	of	of	ADP
fnp-3766	97	30	aβ	aβ	PRON
fnp-3766	97	31	peptide	peptide	NOUN
fnp-3766	97	32	levels	level	NOUN
fnp-3766	97	33	.	.	PUNCT
fnp-3766	98	1	histology	histology	NOUN
fnp-3766	98	2	and	and	CCONJ
fnp-3766	98	3	immunochemistry	immunochemistry	PROPN
fnp-3766	98	4	paraffin	paraffin	NOUN
fnp-3766	98	5	sections	section	NOUN
fnp-3766	98	6	(	(	PUNCT
fnp-3766	98	7	5	5	NUM
fnp-3766	98	8	μm	μm	NOUN
fnp-3766	98	9	)	)	PUNCT
fnp-3766	98	10	were	be	AUX
fnp-3766	98	11	used	use	VERB
fnp-3766	98	12	for	for	ADP
fnp-3766	98	13	all	all	DET
fnp-3766	98	14	the	the	DET
fnp-3766	98	15	histology	histology	NOUN
fnp-3766	98	16	and	and	CCONJ
fnp-3766	98	17	immunochemistry	immunochemistry	PROPN
fnp-3766	98	18	studies	study	NOUN
fnp-3766	98	19	.	.	PUNCT
fnp-3766	99	1	campbell	campbell	PROPN
fnp-3766	99	2	-	-	PUNCT
fnp-3766	99	3	switzer	switzer	PROPN
fnp-3766	99	4	silver	silver	NOUN
fnp-3766	99	5	(	(	PUNCT
fnp-3766	99	6	44	44	NUM
fnp-3766	99	7	)	)	PUNCT
fnp-3766	99	8	and	and	CCONJ
fnp-3766	99	9	thio	thio	NOUN
fnp-3766	99	10	-	-	PUNCT
fnp-3766	99	11	s	s	X
fnp-3766	99	12	(	(	PUNCT
fnp-3766	99	13	37	37	NUM
fnp-3766	99	14	)	)	PUNCT
fnp-3766	99	15	tissue	tissue	NOUN
fnp-3766	99	16	staining	stain	VERB
fnp-3766	99	17	methods	method	NOUN
fnp-3766	99	18	were	be	AUX
fnp-3766	99	19	performed	perform	VERB
fnp-3766	99	20	as	as	ADP
fnp-3766	99	21	previously	previously	ADV
fnp-3766	99	22	described	describe	VERB
fnp-3766	99	23	.	.	PUNCT
fnp-3766	100	1	immunochemistry	immunochemistry	PROPN
fnp-3766	100	2	followed	follow	VERB
fnp-3766	100	3	standard	standard	ADJ
fnp-3766	100	4	protocols	protocol	NOUN
fnp-3766	100	5	described	describe	VERB
fnp-3766	100	6	previously	previously	ADV
fnp-3766	100	7	(	(	PUNCT
fnp-3766	100	8	37	37	NUM
fnp-3766	100	9	)	)	PUNCT
fnp-3766	100	10	.	.	PUNCT
fnp-3766	101	1	to	to	PART
fnp-3766	101	2	assess	assess	VERB
fnp-3766	101	3	amyloid	amyloid	NOUN
fnp-3766	101	4	pathology	pathology	NOUN
fnp-3766	101	5	,	,	PUNCT
fnp-3766	101	6	embedded	embed	VERB
fnp-3766	101	7	sections	section	NOUN
fnp-3766	101	8	were	be	AUX
fnp-3766	101	9	immunohistochemically	immunohistochemically	ADV
fnp-3766	101	10	stained	stain	VERB
fnp-3766	101	11	with	with	ADP
fnp-3766	101	12	a	a	DET
fnp-3766	101	13	biotinylated	biotinylate	VERB
fnp-3766	101	14	pan	pan	NOUN
fnp-3766	101	15	-	-	ADJ
fnp-3766	101	16	aβ	aβ	ADJ
fnp-3766	101	17	antibody	antibody	NOUN
fnp-3766	101	18	ab5	ab5	NOUN
fnp-3766	101	19	(	(	PUNCT
fnp-3766	101	20	1:500	1:500	NUM
fnp-3766	101	21	;	;	PUNCT
fnp-3766	101	22	t.e.g	t.e.g	NOUN
fnp-3766	101	23	.	.	PUNCT
fnp-3766	101	24	)	)	PUNCT
fnp-3766	101	25	and	and	CCONJ
fnp-3766	101	26	developed	develop	VERB
fnp-3766	101	27	using	use	VERB
fnp-3766	101	28	vectastain	vectastain	NOUN
fnp-3766	101	29	elite	elite	ADJ
fnp-3766	101	30	abc	abc	PROPN
fnp-3766	101	31	kit	kit	NOUN
fnp-3766	101	32	(	(	PUNCT
fnp-3766	101	33	vector	vector	NOUN
fnp-3766	101	34	laboratories	laboratory	NOUN
fnp-3766	101	35	,	,	PUNCT
fnp-3766	101	36	burlingame	burlingame	PROPN
fnp-3766	101	37	,	,	PUNCT
fnp-3766	101	38	ca	ca	NOUN
fnp-3766	101	39	)	)	PUNCT
fnp-3766	101	40	followed	follow	VERB
fnp-3766	101	41	with	with	ADP
fnp-3766	101	42	3,3’-diaminobenzidine	3,3’-diaminobenzidine	NUM
fnp-3766	101	43	(	(	PUNCT
fnp-3766	101	44	dab	dab	NOUN
fnp-3766	101	45	)	)	PUNCT
fnp-3766	101	46	substrate	substrate	NOUN
fnp-3766	101	47	(	(	PUNCT
fnp-3766	101	48	vector	vector	NOUN
fnp-3766	101	49	laboratories	laboratory	NOUN
fnp-3766	101	50	,	,	PUNCT
fnp-3766	101	51	burlingame	burlingame	PROPN
fnp-3766	101	52	,	,	PUNCT
fnp-3766	101	53	ca	ca	NOUN
fnp-3766	101	54	)	)	PUNCT
fnp-3766	101	55	.	.	PUNCT
fnp-3766	102	1	to	to	PART
fnp-3766	102	2	evaluate	evaluate	VERB
fnp-3766	102	3	tau	tau	PROPN
fnp-3766	102	4	pathology	pathology	NOUN
fnp-3766	102	5	,	,	PUNCT
fnp-3766	102	6	embedded	embed	VERB
fnp-3766	102	7	sections	section	NOUN
fnp-3766	102	8	were	be	AUX
fnp-3766	102	9	immunohistochemically	immunohistochemically	ADV
fnp-3766	102	10	stained	stain	VERB
fnp-3766	102	11	with	with	ADP
fnp-3766	102	12	7f2	7f2	NUM
fnp-3766	102	13	(	(	PUNCT
fnp-3766	102	14	1:10,000	1:10,000	NUM
fnp-3766	102	15	;	;	PUNCT
fnp-3766	102	16	ben	ben	PROPN
fnp-3766	102	17	giasson	giasson	PROPN
fnp-3766	102	18	(	(	PUNCT
fnp-3766	102	19	39	39	NUM
fnp-3766	102	20	)	)	PUNCT
fnp-3766	102	21	)	)	PUNCT
fnp-3766	102	22	,	,	PUNCT
fnp-3766	102	23	cp27	cp27	PROPN
fnp-3766	102	24	(	(	PUNCT
fnp-3766	102	25	1:1000	1:1000	NUM
fnp-3766	102	26	;	;	PUNCT
fnp-3766	102	27	peter	peter	PROPN
fnp-3766	102	28	davies	davies	PROPN
fnp-3766	102	29	)	)	PUNCT
fnp-3766	102	30	,	,	PUNCT
fnp-3766	102	31	at8	at8	PROPN
fnp-3766	102	32	(	(	PUNCT
fnp-3766	102	33	1:1000	1:1000	NUM
fnp-3766	102	34	;	;	PUNCT
fnp-3766	102	35	thermofisher	thermofisher	ADJ
fnp-3766	102	36	scientific	scientific	NOUN
fnp-3766	102	37	)	)	PUNCT
fnp-3766	102	38	,	,	PUNCT
fnp-3766	102	39	and	and	CCONJ
fnp-3766	102	40	mc1	mc1	PROPN
fnp-3766	102	41	(	(	PUNCT
fnp-3766	102	42	1:1000	1:1000	NUM
fnp-3766	102	43	;	;	PUNCT
fnp-3766	102	44	peter	peter	PROPN
fnp-3766	102	45	davies	davy	NOUN
fnp-3766	102	46	)	)	PUNCT
fnp-3766	102	47	.	.	PUNCT
fnp-3766	103	1	to	to	PART
fnp-3766	103	2	assess	assess	VERB
fnp-3766	103	3	αsyn	αsyn	ADJ
fnp-3766	103	4	pathology	pathology	NOUN
fnp-3766	103	5	,	,	PUNCT
fnp-3766	103	6	sections	section	NOUN
fnp-3766	103	7	were	be	AUX
fnp-3766	103	8	stained	stain	VERB
fnp-3766	103	9	with	with	ADP
fnp-3766	103	10	9c10	9c10	PROPN
fnp-3766	103	11	(	(	PUNCT
fnp-3766	103	12	1:1000	1:1000	NUM
fnp-3766	103	13	;	;	PUNCT
fnp-3766	103	14	ben	ben	PROPN
fnp-3766	103	15	giasson	giasson	PROPN
fnp-3766	103	16	)	)	PUNCT
fnp-3766	103	17	(	(	PUNCT
fnp-3766	103	18	31	31	NUM
fnp-3766	103	19	)	)	PUNCT
fnp-3766	103	20	.	.	PUNCT
fnp-3766	104	1	after	after	ADP
fnp-3766	104	2	development	development	NOUN
fnp-3766	104	3	by	by	ADP
fnp-3766	104	4	3,3’-diaminobenzidine	3,3’-diaminobenzidine	NUM
fnp-3766	104	5	(	(	PUNCT
fnp-3766	104	6	dab	dab	PROPN
fnp-3766	104	7	)	)	PUNCT
fnp-3766	104	8	(	(	PUNCT
fnp-3766	104	9	vector	vector	NOUN
fnp-3766	104	10	laboratories	laboratory	NOUN
fnp-3766	104	11	,	,	PUNCT
fnp-3766	104	12	burlingame	burlingame	PROPN
fnp-3766	104	13	,	,	PUNCT
fnp-3766	104	14	ca	ca	NOUN
fnp-3766	104	15	)	)	PUNCT
fnp-3766	104	16	substrate	substrate	NOUN
fnp-3766	104	17	and	and	CCONJ
fnp-3766	104	18	counterstaining	counterstaine	VERB
fnp-3766	104	19	with	with	ADP
fnp-3766	104	20	hematoxylin	hematoxylin	NOUN
fnp-3766	104	21	,	,	PUNCT
fnp-3766	104	22	the	the	DET
fnp-3766	104	23	slides	slide	NOUN
fnp-3766	104	24	were	be	AUX
fnp-3766	104	25	coverslipped	coverslippe	VERB
fnp-3766	104	26	and	and	CCONJ
fnp-3766	104	27	images	image	NOUN
fnp-3766	104	28	were	be	AUX
fnp-3766	104	29	taken	take	VERB
fnp-3766	104	30	using	use	VERB
fnp-3766	104	31	an	an	DET
fnp-3766	104	32	olympus	olympus	PROPN
fnp-3766	104	33	bx60	bx60	PROPN
fnp-3766	104	34	microscope	microscope	NOUN
fnp-3766	104	35	or	or	CCONJ
fnp-3766	104	36	scanned	scan	VERB
fnp-3766	104	37	by	by	ADP
fnp-3766	104	38	aperio	aperio	PROPN
fnp-3766	104	39	®	®	PROPN
fnp-3766	104	40	xt	xt	PROPN
fnp-3766	104	41	system	system	NOUN
fnp-3766	104	42	(	(	PUNCT
fnp-3766	104	43	leica	leica	PROPN
fnp-3766	104	44	biosystems	biosystems	PROPN
fnp-3766	104	45	,	,	PUNCT
fnp-3766	104	46	buffalo	buffalo	NOUN
fnp-3766	104	47	gove	gove	PROPN
fnp-3766	104	48	,	,	PUNCT
fnp-3766	104	49	il	il	PROPN
fnp-3766	104	50	,	,	PUNCT
fnp-3766	104	51	usa	usa	PROPN
fnp-3766	104	52	)	)	PUNCT
fnp-3766	104	53	or	or	CCONJ
fnp-3766	104	54	zeiss	zeiss	PROPN
fnp-3766	104	55	microscope	microscope	NOUN
fnp-3766	104	56	(	(	PUNCT
fnp-3766	104	57	carl	carl	PROPN
fnp-3766	104	58	zeiss	zeiss	PROPN
fnp-3766	104	59	,	,	PUNCT
fnp-3766	104	60	oberkochen	oberkochen	ADV
fnp-3766	104	61	,	,	PUNCT
fnp-3766	104	62	germany	germany	PROPN
fnp-3766	104	63	)	)	PUNCT
fnp-3766	104	64	and	and	CCONJ
fnp-3766	104	65	analyzed	analyze	VERB
fnp-3766	104	66	using	use	VERB
fnp-3766	104	67	the	the	DET
fnp-3766	104	68	zen	zen	PROPN
fnp-3766	104	69	2.6	2.6	NUM
fnp-3766	104	70	program	program	NOUN
fnp-3766	104	71	(	(	PUNCT
fnp-3766	104	72	carl	carl	PROPN
fnp-3766	104	73	zeiss	zeiss	PROPN
fnp-3766	104	74	,	,	PUNCT
fnp-3766	104	75	oberkochen	oberkochen	ADV
fnp-3766	104	76	,	,	PUNCT
fnp-3766	104	77	germany	germany	PROPN
fnp-3766	104	78	)	)	PUNCT
fnp-3766	104	79	.	.	PUNCT
fnp-3766	105	1	blinded	blind	VERB
fnp-3766	105	2	observers	observer	NOUN
fnp-3766	105	3	then	then	ADV
fnp-3766	105	4	reviewed	review	VERB
fnp-3766	105	5	the	the	DET
fnp-3766	105	6	images	image	NOUN
fnp-3766	105	7	and	and	CCONJ
fnp-3766	105	8	scored	score	VERB
fnp-3766	105	9	the	the	DET
fnp-3766	105	10	burden	burden	NOUN
fnp-3766	105	11	of	of	ADP
fnp-3766	105	12	aβ	aβ	DET
fnp-3766	105	13	pathology	pathology	NOUN
fnp-3766	105	14	based	base	VERB
fnp-3766	105	15	on	on	ADP
fnp-3766	105	16	the	the	DET
fnp-3766	105	17	following	follow	VERB
fnp-3766	105	18	criteria	criterion	NOUN
fnp-3766	105	19	:	:	PUNCT
fnp-3766	105	20	“	"	PUNCT
fnp-3766	105	21	+	+	ADJ
fnp-3766	105	22	+	+	ADJ
fnp-3766	105	23	+	+	ADJ
fnp-3766	105	24	”	"	PUNCT
fnp-3766	105	25	=	=	SYM
fnp-3766	105	26	heavy	heavy	ADJ
fnp-3766	105	27	aβ	aβ	NOUN
fnp-3766	105	28	burden	burden	NOUN
fnp-3766	105	29	with	with	ADP
fnp-3766	105	30	too	too	ADV
fnp-3766	105	31	many	many	ADJ
fnp-3766	105	32	deposits	deposit	NOUN
fnp-3766	105	33	to	to	PART
fnp-3766	105	34	count	count	VERB
fnp-3766	105	35	.	.	PUNCT
fnp-3766	106	1	“	"	PUNCT
fnp-3766	106	2	+	+	SYM
fnp-3766	106	3	+	+	NOUN
fnp-3766	106	4	”	"	PUNCT
fnp-3766	106	5	=	=	VERB
fnp-3766	106	6	abundant	abundant	ADJ
fnp-3766	106	7	pathology	pathology	NOUN
fnp-3766	106	8	with	with	ADP
fnp-3766	106	9	>	>	SYM
fnp-3766	106	10	30	30	NUM
fnp-3766	106	11	deposits	deposit	NOUN
fnp-3766	106	12	per	per	ADP
fnp-3766	106	13	section	section	NOUN
fnp-3766	106	14	.	.	PUNCT
fnp-3766	107	1	“	"	PUNCT
fnp-3766	107	2	+	+	ADJ
fnp-3766	107	3	”	"	PUNCT
fnp-3766	107	4	=	=	SYM
fnp-3766	107	5	consistent	consistent	ADJ
fnp-3766	107	6	pathology	pathology	NOUN
fnp-3766	107	7	with	with	ADP
fnp-3766	107	8	>	>	SYM
fnp-3766	107	9	5	5	NUM
fnp-3766	107	10	deposits	deposit	NOUN
fnp-3766	107	11	per	per	ADP
fnp-3766	107	12	section	section	NOUN
fnp-3766	107	13	.	.	PUNCT
fnp-3766	108	1	“	"	PUNCT
fnp-3766	108	2	+	+	PROPN
fnp-3766	108	3	/-	/-	PRON
fnp-3766	108	4	”	"	PUNCT
fnp-3766	108	5	=	=	SYM
fnp-3766	108	6	inconsistent	inconsistent	ADJ
fnp-3766	108	7	pathology	pathology	NOUN
fnp-3766	108	8	with	with	ADP
fnp-3766	108	9	<3	<3	ADJ
fnp-3766	108	10	deposits	deposit	NOUN
fnp-3766	108	11	per	per	ADP
fnp-3766	108	12	section	section	NOUN
fnp-3766	108	13	.	.	PUNCT
fnp-3766	109	1	brain	brain	NOUN
fnp-3766	109	2	amyloid	amyloid	NOUN
fnp-3766	109	3	extraction	extraction	NOUN
fnp-3766	109	4	human	human	ADJ
fnp-3766	109	5	brain	brain	NOUN
fnp-3766	109	6	samples	sample	NOUN
fnp-3766	109	7	were	be	AUX
fnp-3766	109	8	originally	originally	ADV
fnp-3766	109	9	analyzed	analyze	VERB
fnp-3766	109	10	by	by	ADP
fnp-3766	109	11	moore	moore	PROPN
fnp-3766	109	12	(	(	PUNCT
fnp-3766	109	13	25	25	NUM
fnp-3766	109	14	)	)	PUNCT
fnp-3766	109	15	.	.	PUNCT
fnp-3766	110	1	briefly	briefly	ADV
fnp-3766	110	2	,	,	PUNCT
fnp-3766	110	3	frozen	frozen	ADJ
fnp-3766	110	4	pre	pre	ADJ
fnp-3766	110	5	-	-	ADJ
fnp-3766	110	6	frontal	frontal	ADJ
fnp-3766	110	7	cortex	cortex	NOUN
fnp-3766	110	8	tissue	tissue	NOUN
fnp-3766	110	9	was	be	AUX
fnp-3766	110	10	cryo	cryo	NOUN
fnp-3766	110	11	-	-	PUNCT
fnp-3766	110	12	pulverized	pulverize	VERB
fnp-3766	110	13	in	in	ADP
fnp-3766	110	14	liquid	liquid	ADJ
fnp-3766	110	15	nitrogen	nitrogen	NOUN
fnp-3766	110	16	and	and	CCONJ
fnp-3766	110	17	then	then	ADV
fnp-3766	110	18	sequentially	sequentially	ADV
fnp-3766	110	19	extracted	extract	VERB
fnp-3766	110	20	with	with	ADP
fnp-3766	110	21	tris	tris	ADJ
fnp-3766	110	22	-	-	PUNCT
fnp-3766	110	23	buffered	buffer	VERB
fnp-3766	110	24	saline	saline	NOUN
fnp-3766	110	25	(	(	PUNCT
fnp-3766	110	26	tbs	tbs	NOUN
fnp-3766	110	27	)	)	PUNCT
fnp-3766	110	28	,	,	PUNCT
fnp-3766	110	29	radioimmunoprecipitation	radioimmunoprecipitation	NOUN
fnp-3766	110	30	buffer	buffer	NOUN
fnp-3766	110	31	(	(	PUNCT
fnp-3766	110	32	ripa	ripa	NOUN
fnp-3766	110	33	)	)	PUNCT
fnp-3766	110	34	,	,	PUNCT
fnp-3766	110	35	2	2	NUM
fnp-3766	110	36	%	%	NOUN
fnp-3766	110	37	sodium	sodium	NOUN
fnp-3766	110	38	dodecyl	dodecyl	NOUN
fnp-3766	110	39	sulfate	sulfate	NOUN
fnp-3766	110	40	(	(	PUNCT
fnp-3766	110	41	sds	sds	PROPN
fnp-3766	110	42	)	)	PUNCT
fnp-3766	110	43	,	,	PUNCT
fnp-3766	110	44	and	and	CCONJ
fnp-3766	110	45	70	70	NUM
fnp-3766	110	46	%	%	NOUN
fnp-3766	110	47	formic	formic	ADJ
fnp-3766	110	48	acid	acid	NOUN
fnp-3766	110	49	(	(	PUNCT
fnp-3766	110	50	fa	fa	NOUN
fnp-3766	110	51	)	)	PUNCT
fnp-3766	110	52	containing	contain	VERB
fnp-3766	110	53	protease	protease	NOUN
fnp-3766	110	54	inhibitor	inhibitor	NOUN
fnp-3766	110	55	cocktail	cocktail	NOUN
fnp-3766	110	56	(	(	PUNCT
fnp-3766	110	57	roche	roche	PROPN
fnp-3766	110	58	,	,	PUNCT
fnp-3766	110	59	indianapolis	indianapolis	PROPN
fnp-3766	110	60	,	,	PUNCT
fnp-3766	110	61	in	in	ADP
fnp-3766	110	62	,	,	PUNCT
fnp-3766	110	63	usa	usa	PROPN
fnp-3766	110	64	)	)	PUNCT
fnp-3766	110	65	.	.	PUNCT
fnp-3766	111	1	after	after	ADP
fnp-3766	111	2	harvesting	harvest	VERB
fnp-3766	111	3	the	the	DET
fnp-3766	111	4	mouse	mouse	NOUN
fnp-3766	111	5	brain	brain	NOUN
fnp-3766	111	6	,	,	PUNCT
fnp-3766	111	7	the	the	DET
fnp-3766	111	8	left	left	NOUN
fnp-3766	111	9	hemisphere	hemisphere	ADV
fnp-3766	111	10	was	be	AUX
fnp-3766	111	11	flash	flash	NOUN
fnp-3766	111	12	-	-	PUNCT
fnp-3766	111	13	frozen	frozen	ADJ
fnp-3766	111	14	in	in	ADP
fnp-3766	111	15	isopentane	isopentane	NOUN
fnp-3766	111	16	.	.	PUNCT
fnp-3766	112	1	the	the	DET
fnp-3766	112	2	frozen	frozen	ADJ
fnp-3766	112	3	cortex	cortex	NOUN
fnp-3766	112	4	was	be	AUX
fnp-3766	112	5	sequentially	sequentially	ADV
fnp-3766	112	6	extracted	extract	VERB
fnp-3766	112	7	with	with	ADP
fnp-3766	112	8	protease	protease	NOUN
fnp-3766	112	9	inhibitor	inhibitor	NOUN
fnp-3766	112	10	cocktail	cocktail	NOUN
fnp-3766	112	11	(	(	PUNCT
fnp-3766	112	12	roche	roche	NOUN
fnp-3766	112	13	)	)	PUNCT
fnp-3766	112	14	containing	contain	VERB
fnp-3766	112	15	tris	tris	NOUN
fnp-3766	112	16	-	-	PUNCT
fnp-3766	112	17	buffered	buffer	VERB
fnp-3766	112	18	saline	saline	NOUN
fnp-3766	112	19	,	,	PUNCT
fnp-3766	112	20	ripa	ripa	NOUN
fnp-3766	112	21	buffer	buffer	NOUN
fnp-3766	112	22	,	,	PUNCT
fnp-3766	112	23	2	2	NUM
fnp-3766	112	24	%	%	NOUN
fnp-3766	112	25	sds	sds	NOUN
fnp-3766	112	26	,	,	PUNCT
fnp-3766	112	27	and	and	CCONJ
fnp-3766	112	28	70	70	NUM
fnp-3766	112	29	%	%	NOUN
fnp-3766	112	30	formic	formic	ADJ
fnp-3766	112	31	acid	acid	NOUN
fnp-3766	112	32	(	(	PUNCT
fnp-3766	112	33	fa	fa	NOUN
fnp-3766	112	34	)	)	PUNCT
fnp-3766	112	35	as	as	SCONJ
fnp-3766	112	36	described	describe	VERB
fnp-3766	112	37	previously	previously	ADV
fnp-3766	112	38	at	at	ADP
fnp-3766	112	39	a	a	DET
fnp-3766	112	40	concentration	concentration	NOUN
fnp-3766	112	41	of	of	ADP
fnp-3766	112	42	150	150	NUM
fnp-3766	112	43	mg	mg	NUM
fnp-3766	112	44	/	/	SYM
fnp-3766	112	45	ml	ml	PROPN
fnp-3766	112	46	(	(	PUNCT
fnp-3766	112	47	25	25	NUM
fnp-3766	112	48	)	)	PUNCT
fnp-3766	112	49	.	.	PUNCT
fnp-3766	113	1	elisa	elisa	VERB
fnp-3766	113	2	aβ	aβ	NOUN
fnp-3766	113	3	levels	level	NOUN
fnp-3766	113	4	from	from	ADP
fnp-3766	113	5	the	the	DET
fnp-3766	113	6	2	2	NUM
fnp-3766	113	7	%	%	NOUN
fnp-3766	113	8	sds	sds	NOUN
fnp-3766	113	9	and	and	CCONJ
fnp-3766	113	10	70	70	NUM
fnp-3766	113	11	%	%	NOUN
fnp-3766	113	12	fa	fa	NOUN
fnp-3766	113	13	extracted	extract	VERB
fnp-3766	113	14	samples	sample	NOUN
fnp-3766	113	15	were	be	AUX
fnp-3766	113	16	quantified	quantify	VERB
fnp-3766	113	17	by	by	ADP
fnp-3766	113	18	sandwich	sandwich	NOUN
fnp-3766	113	19	elisa	elisa	PROPN
fnp-3766	113	20	as	as	SCONJ
fnp-3766	113	21	described	describe	VERB
fnp-3766	113	22	previously	previously	ADV
fnp-3766	113	23	(	(	PUNCT
fnp-3766	113	24	25	25	NUM
fnp-3766	113	25	)	)	PUNCT
fnp-3766	113	26	.	.	PUNCT
fnp-3766	114	1	total	total	NOUN
fnp-3766	114	2	aβ	aβ	NOUN
fnp-3766	114	3	was	be	AUX
fnp-3766	114	4	captured	capture	VERB
fnp-3766	114	5	with	with	ADP
fnp-3766	114	6	mab	mab	NOUN
fnp-3766	114	7	ab9	ab9	NOUN
fnp-3766	114	8	and	and	CCONJ
fnp-3766	114	9	detected	detect	VERB
fnp-3766	114	10	by	by	ADP
fnp-3766	114	11	hrp	hrp	PROPN
fnp-3766	114	12	-	-	PUNCT
fnp-3766	114	13	conjugated	conjugate	VERB
fnp-3766	114	14	mab	mab	X
fnp-3766	114	15	4g8	4g8	NUM
fnp-3766	114	16	(	(	PUNCT
fnp-3766	114	17	human	human	ADJ
fnp-3766	114	18	aβ17	aβ17	PROPN
fnp-3766	114	19	-	-	PUNCT
fnp-3766	114	20	24	24	NUM
fnp-3766	114	21	;	;	PUNCT
fnp-3766	114	22	covance	covance	NOUN
fnp-3766	114	23	,	,	PUNCT
fnp-3766	114	24	princeton	princeton	PROPN
fnp-3766	114	25	,	,	PUNCT
fnp-3766	114	26	nj	nj	PROPN
fnp-3766	114	27	,	,	PUNCT
fnp-3766	114	28	usa	usa	PROPN
fnp-3766	114	29	)	)	PUNCT
fnp-3766	114	30	;	;	PUNCT
fnp-3766	114	31	aβ1	aβ1	NOUN
fnp-3766	114	32	-	-	SYM
fnp-3766	114	33	40	40	NUM
fnp-3766	114	34	was	be	AUX
fnp-3766	114	35	captured	capture	VERB
fnp-3766	114	36	with	with	ADP
fnp-3766	114	37	monoclonal	monoclonal	NOUN
fnp-3766	114	38	antibody	antibody	NOUN
fnp-3766	114	39	(	(	PUNCT
fnp-3766	114	40	mab	mab	NOUN
fnp-3766	114	41	)	)	PUNCT
fnp-3766	114	42	ab9	ab9	NOUN
fnp-3766	114	43	(	(	PUNCT
fnp-3766	114	44	human	human	ADJ
fnp-3766	114	45	aβ1	aβ1	NOUN
fnp-3766	114	46	-	-	PUNCT
fnp-3766	114	47	16	16	NUM
fnp-3766	114	48	;	;	PUNCT
fnp-3766	114	49	t.e	t.e	PROPN
fnp-3766	114	50	.	.	PROPN
fnp-3766	114	51	golde	golde	PROPN
fnp-3766	114	52	)	)	PUNCT
fnp-3766	114	53	and	and	CCONJ
fnp-3766	114	54	detected	detect	VERB
fnp-3766	114	55	by	by	ADP
fnp-3766	114	56	horseradish	horseradish	ADJ
fnp-3766	114	57	peroxidase	peroxidase	NOUN
fnp-3766	114	58	(	(	PUNCT
fnp-3766	114	59	hrp)-conjugated	hrp)-conjugated	ADJ
fnp-3766	114	60	mab	mab	NOUN
fnp-3766	114	61	13.1.1	13.1.1	X
fnp-3766	114	62	(	(	PUNCT
fnp-3766	114	63	human	human	PROPN
fnp-3766	114	64	aβ35	aβ35	PROPN
fnp-3766	114	65	-	-	PUNCT
fnp-3766	114	66	40	40	NUM
fnp-3766	114	67	specific	specific	ADJ
fnp-3766	114	68	;	;	PUNCT
fnp-3766	114	69	t.e	t.e	PROPN
fnp-3766	114	70	.	.	PUNCT
fnp-3766	114	71	golde	golde	PROPN
fnp-3766	114	72	)	)	PUNCT
fnp-3766	114	73	;	;	PUNCT
fnp-3766	114	74	aβ1	aβ1	NOUN
fnp-3766	114	75	-	-	PUNCT
fnp-3766	114	76	42	42	NUM
fnp-3766	114	77	was	be	AUX
fnp-3766	114	78	captured	capture	VERB
fnp-3766	114	79	with	with	ADP
fnp-3766	114	80	mab	mab	PROPN
fnp-3766	114	81	2.1.3	2.1.3	NUM
fnp-3766	114	82	(	(	PUNCT
fnp-3766	114	83	human	human	PROPN
fnp-3766	114	84	aβ35	aβ35	PROPN
fnp-3766	114	85	-	-	PUNCT
fnp-3766	114	86	42	42	NUM
fnp-3766	114	87	specific	specific	ADJ
fnp-3766	114	88	;	;	PUNCT
fnp-3766	114	89	t.e	t.e	PROPN
fnp-3766	114	90	.	.	PROPN
fnp-3766	114	91	golde	golde	PROPN
fnp-3766	114	92	)	)	PUNCT
fnp-3766	114	93	and	and	CCONJ
fnp-3766	114	94	detected	detect	VERB
fnp-3766	114	95	by	by	ADP
fnp-3766	114	96	hrp	hrp	PROPN
fnp-3766	114	97	-	-	PUNCT
fnp-3766	114	98	conjugated	conjugate	VERB
fnp-3766	114	99	mab	mab	PROPN
fnp-3766	114	100	ab9	ab9	PROPN
fnp-3766	114	101	.	.	PUNCT
fnp-3766	115	1	elisa	elisa	PROPN
fnp-3766	115	2	results	result	NOUN
fnp-3766	115	3	were	be	AUX
fnp-3766	115	4	analyzed	analyze	VERB
fnp-3766	115	5	using	use	VERB
fnp-3766	115	6	softmax	softmax	ADJ
fnp-3766	115	7	pro	pro	X
fnp-3766	115	8	software	software	NOUN
fnp-3766	115	9	(	(	PUNCT
fnp-3766	115	10	molecular	molecular	ADJ
fnp-3766	115	11	devices	device	NOUN
fnp-3766	115	12	)	)	PUNCT
fnp-3766	115	13	.	.	PUNCT
fnp-3766	116	1	contextual	contextual	ADJ
fnp-3766	116	2	fear	fear	NOUN
fnp-3766	116	3	conditioning	condition	VERB
fnp-3766	116	4	transgenic	transgenic	NOUN
fnp-3766	116	5	prp.appsi	prp.appsi	NOUN
fnp-3766	116	6	and	and	CCONJ
fnp-3766	116	7	nontransgenic	nontransgenic	ADJ
fnp-3766	116	8	littermates	littermate	NOUN
fnp-3766	116	9	,	,	PUNCT
fnp-3766	116	10	seeded	seed	VERB
fnp-3766	116	11	with	with	ADP
fnp-3766	116	12	ad	ad	NOUN
fnp-3766	116	13	cases	case	NOUN
fnp-3766	116	14	1	1	NUM
fnp-3766	116	15	and	and	CCONJ
fnp-3766	116	16	2	2	NUM
fnp-3766	116	17	,	,	PUNCT
fnp-3766	116	18	and	and	CCONJ
fnp-3766	116	19	ndc	ndc	NOUN
fnp-3766	116	20	case	case	NOUN
fnp-3766	116	21	7	7	NUM
fnp-3766	116	22	,	,	PUNCT
fnp-3766	116	23	were	be	AUX
fnp-3766	116	24	aged	age	VERB
fnp-3766	116	25	to	to	ADP
fnp-3766	116	26	12	12	NUM
fnp-3766	116	27	months	month	NOUN
fnp-3766	116	28	and	and	CCONJ
fnp-3766	116	29	subjected	subject	VERB
fnp-3766	116	30	to	to	ADP
fnp-3766	116	31	contextual	contextual	ADJ
fnp-3766	116	32	fear	fear	NOUN
fnp-3766	116	33	conditioning	conditioning	NOUN
fnp-3766	116	34	as	as	ADP
fnp-3766	116	35	previously	previously	ADV
fnp-3766	116	36	described	describe	VERB
fnp-3766	116	37	(	(	PUNCT
fnp-3766	116	38	45	45	NUM
fnp-3766	116	39	,	,	PUNCT
fnp-3766	116	40	46	46	NUM
fnp-3766	116	41	)	)	PUNCT
fnp-3766	116	42	.	.	PUNCT
fnp-3766	117	1	briefly	briefly	ADV
fnp-3766	117	2	,	,	PUNCT
fnp-3766	117	3	in	in	ADP
fnp-3766	117	4	the	the	DET
fnp-3766	117	5	contextual	contextual	ADJ
fnp-3766	117	6	fear	fear	NOUN
fnp-3766	117	7	conditioning	conditioning	NOUN
fnp-3766	117	8	test	test	NOUN
fnp-3766	117	9	,	,	PUNCT
fnp-3766	117	10	mice	mouse	NOUN
fnp-3766	117	11	learn	learn	VERB
fnp-3766	117	12	the	the	DET
fnp-3766	117	13	association	association	NOUN
fnp-3766	117	14	between	between	ADP
fnp-3766	117	15	the	the	DET
fnp-3766	117	16	training	training	NOUN
fnp-3766	117	17	chamber	chamber	NOUN
fnp-3766	117	18	,	,	PUNCT
fnp-3766	117	19	which	which	PRON
fnp-3766	117	20	represents	represent	VERB
fnp-3766	117	21	an	an	DET
fnp-3766	117	22	initially	initially	ADV
fnp-3766	117	23	neutral	neutral	ADJ
fnp-3766	117	24	conditional	conditional	ADJ
fnp-3766	117	25	stimulus	stimulus	NOUN
fnp-3766	117	26	(	(	PUNCT
fnp-3766	117	27	cs	cs	PROPN
fnp-3766	117	28	)	)	PUNCT
fnp-3766	117	29	and	and	CCONJ
fnp-3766	117	30	an	an	DET
fnp-3766	117	31	aversive	aversive	ADJ
fnp-3766	117	32	,	,	PUNCT
fnp-3766	117	33	brief	brief	ADJ
fnp-3766	117	34	electric	electric	ADJ
fnp-3766	117	35	foot	foot	NOUN
fnp-3766	117	36	-	-	PUNCT
fnp-3766	117	37	shock	shock	NOUN
fnp-3766	117	38	,	,	PUNCT
fnp-3766	117	39	unconditional	unconditional	ADJ
fnp-3766	117	40	stimulus	stimulus	NOUN
fnp-3766	117	41	(	(	PUNCT
fnp-3766	117	42	us	us	PROPN
fnp-3766	117	43	)	)	PUNCT
fnp-3766	117	44	,	,	PUNCT
fnp-3766	117	45	which	which	PRON
fnp-3766	117	46	takes	take	VERB
fnp-3766	117	47	place	place	NOUN
fnp-3766	117	48	in	in	ADP
fnp-3766	117	49	the	the	DET
fnp-3766	117	50	training	training	NOUN
fnp-3766	117	51	context	context	NOUN
fnp-3766	117	52	.	.	PUNCT
fnp-3766	118	1	we	we	PRON
fnp-3766	118	2	have	have	AUX
fnp-3766	118	3	previously	previously	ADV
fnp-3766	118	4	established	establish	VERB
fnp-3766	118	5	that	that	SCONJ
fnp-3766	118	6	0.45	0.45	NUM
fnp-3766	118	7	ma	ma	PROPN
fnp-3766	118	8	electric	electric	PROPN
fnp-3766	118	9	current	current	PROPN
fnp-3766	118	10	elicits	elicit	VERB
fnp-3766	118	11	robust	robust	ADJ
fnp-3766	118	12	avoidance	avoidance	NOUN
fnp-3766	118	13	response	response	NOUN
fnp-3766	118	14	and	and	CCONJ
fnp-3766	118	15	results	result	NOUN
fnp-3766	118	16	in	in	ADP
fnp-3766	118	17	strong	strong	ADJ
fnp-3766	118	18	freezing	freezing	ADJ
fnp-3766	118	19	response	response	NOUN
fnp-3766	118	20	after	after	ADP
fnp-3766	118	21	2	2	NUM
fnp-3766	118	22	cs	cs	PROPN
fnp-3766	118	23	-	-	PUNCT
fnp-3766	118	24	us	us	PROPN
fnp-3766	118	25	pairings	pairing	NOUN
fnp-3766	118	26	(	(	PUNCT
fnp-3766	118	27	45	45	NUM
fnp-3766	118	28	)	)	PUNCT
fnp-3766	118	29	.	.	PUNCT
fnp-3766	119	1	during	during	ADP
fnp-3766	119	2	the	the	DET
fnp-3766	119	3	training	training	NOUN
fnp-3766	119	4	session	session	NOUN
fnp-3766	119	5	,	,	PUNCT
fnp-3766	119	6	mice	mouse	NOUN
fnp-3766	119	7	were	be	AUX
fnp-3766	119	8	allowed	allow	VERB
fnp-3766	119	9	to	to	PART
fnp-3766	119	10	explore	explore	VERB
fnp-3766	119	11	the	the	DET
fnp-3766	119	12	training	training	NOUN
fnp-3766	119	13	chamber	chamber	NOUN
fnp-3766	119	14	for	for	ADP
fnp-3766	119	15	120	120	NUM
fnp-3766	119	16	sec	sec	PROPN
fnp-3766	119	17	,	,	PUNCT
fnp-3766	119	18	with	with	ADP
fnp-3766	119	19	a	a	DET
fnp-3766	119	20	2	2	NUM
fnp-3766	119	21	sec	sec	PROPN
fnp-3766	119	22	foot	foot	NOUN
fnp-3766	119	23	shock	shock	NOUN
fnp-3766	119	24	immediately	immediately	ADV
fnp-3766	119	25	following	follow	VERB
fnp-3766	119	26	a	a	DET
fnp-3766	119	27	30	30	NUM
fnp-3766	119	28	sec	sec	PROPN
fnp-3766	119	29	tone	tone	NOUN
fnp-3766	119	30	(	(	PUNCT
fnp-3766	119	31	80	80	NUM
fnp-3766	119	32	db	db	NOUN
fnp-3766	119	33	)	)	PUNCT
fnp-3766	119	34	(	(	PUNCT
fnp-3766	119	35	day	day	NOUN
fnp-3766	119	36	1	1	NUM
fnp-3766	119	37	;	;	PUNCT
fnp-3766	119	38	see	see	VERB
fnp-3766	119	39	fig	fig	NOUN
fnp-3766	119	40	.	.	PUNCT
fnp-3766	120	1	4a	4a	NUM
fnp-3766	120	2	)	)	PUNCT
fnp-3766	120	3	.	.	PUNCT
fnp-3766	121	1	the	the	DET
fnp-3766	121	2	mice	mouse	NOUN
fnp-3766	121	3	recover	recover	VERB
fnp-3766	121	4	for	for	ADP
fnp-3766	121	5	60	60	NUM
fnp-3766	121	6	sec	sec	PROPN
fnp-3766	121	7	and	and	CCONJ
fnp-3766	121	8	then	then	ADV
fnp-3766	121	9	receive	receive	VERB
fnp-3766	121	10	another	another	DET
fnp-3766	121	11	2	2	NUM
fnp-3766	121	12	sec	sec	PROPN
fnp-3766	121	13	foot	foot	NOUN
fnp-3766	121	14	shock	shock	NOUN
fnp-3766	121	15	following	follow	VERB
fnp-3766	121	16	a	a	DET
fnp-3766	121	17	30	30	NUM
fnp-3766	121	18	sec	sec	PROPN
fnp-3766	121	19	tone	tone	NOUN
fnp-3766	121	20	.	.	PUNCT
fnp-3766	122	1	the	the	DET
fnp-3766	122	2	final	final	ADJ
fnp-3766	122	3	post	post	NOUN
fnp-3766	122	4	-	-	ADJ
fnp-3766	122	5	us	us	ADJ
fnp-3766	122	6	period	period	NOUN
fnp-3766	122	7	is	be	AUX
fnp-3766	122	8	60	60	NUM
fnp-3766	122	9	sec	sec	PROPN
fnp-3766	122	10	.	.	PROPN
fnp-3766	123	1	for	for	ADP
fnp-3766	123	2	the	the	DET
fnp-3766	123	3	context	context	NOUN
fnp-3766	123	4	test	test	NOUN
fnp-3766	123	5	session	session	NOUN
fnp-3766	123	6	,	,	PUNCT
fnp-3766	123	7	on	on	ADP
fnp-3766	123	8	day	day	NOUN
fnp-3766	123	9	3	3	NUM
fnp-3766	123	10	,	,	PUNCT
fnp-3766	123	11	mice	mouse	NOUN
fnp-3766	123	12	were	be	AUX
fnp-3766	123	13	exposed	expose	VERB
fnp-3766	123	14	to	to	ADP
fnp-3766	123	15	the	the	DET
fnp-3766	123	16	same	same	ADJ
fnp-3766	123	17	training	training	NOUN
fnp-3766	123	18	context	context	NOUN
fnp-3766	123	19	and	and	CCONJ
fnp-3766	123	20	the	the	DET
fnp-3766	123	21	freezing	freezing	ADJ
fnp-3766	123	22	presentation	presentation	NOUN
fnp-3766	123	23	during	during	ADP
fnp-3766	123	24	the	the	DET
fnp-3766	123	25	300	300	NUM
fnp-3766	123	26	sec	sec	PROPN
fnp-3766	123	27	was	be	AUX
fnp-3766	123	28	recorded	record	VERB
fnp-3766	123	29	by	by	ADP
fnp-3766	123	30	an	an	DET
fnp-3766	123	31	image	image	NOUN
fnp-3766	123	32	analysis	analysis	NOUN
fnp-3766	123	33	system	system	NOUN
fnp-3766	123	34	(	(	PUNCT
fnp-3766	123	35	freezeframe	freezeframe	PROPN
fnp-3766	123	36	,	,	PUNCT
fnp-3766	123	37	actimetrics	actimetrics	PROPN
fnp-3766	123	38	)	)	PUNCT
fnp-3766	123	39	.	.	PUNCT
fnp-3766	124	1	on	on	ADP
fnp-3766	124	2	day	day	NOUN
fnp-3766	124	3	4	4	NUM
fnp-3766	124	4	,	,	PUNCT
fnp-3766	124	5	mice	mouse	NOUN
fnp-3766	124	6	experienced	experience	VERB
fnp-3766	124	7	the	the	DET
fnp-3766	124	8	tone	tone	NOUN
fnp-3766	124	9	session	session	NOUN
fnp-3766	124	10	,	,	PUNCT
fnp-3766	124	11	and	and	CCONJ
fnp-3766	124	12	were	be	AUX
fnp-3766	124	13	placed	place	VERB
fnp-3766	124	14	in	in	ADP
fnp-3766	124	15	a	a	DET
fnp-3766	124	16	modified	modified	ADJ
fnp-3766	124	17	chamber	chamber	NOUN
fnp-3766	124	18	(	(	PUNCT
fnp-3766	124	19	altered	alter	VERB
fnp-3766	124	20	inserts	insert	NOUN
fnp-3766	124	21	and	and	CCONJ
fnp-3766	124	22	smell	smell	NOUN
fnp-3766	124	23	)	)	PUNCT
fnp-3766	124	24	,	,	PUNCT
fnp-3766	124	25	during	during	ADP
fnp-3766	124	26	the	the	DET
fnp-3766	124	27	first	first	ADJ
fnp-3766	124	28	180	180	NUM
fnp-3766	124	29	sec	sec	PROPN
fnp-3766	124	30	the	the	DET
fnp-3766	124	31	mice	mouse	NOUN
fnp-3766	124	32	were	be	AUX
fnp-3766	124	33	allowed	allow	VERB
fnp-3766	124	34	to	to	PART
fnp-3766	124	35	explore	explore	VERB
fnp-3766	124	36	the	the	DET
fnp-3766	124	37	new	new	ADJ
fnp-3766	124	38	environment	environment	NOUN
fnp-3766	124	39	.	.	PUNCT
fnp-3766	125	1	during	during	ADP
fnp-3766	125	2	the	the	DET
fnp-3766	125	3	second	second	ADJ
fnp-3766	125	4	180	180	NUM
fnp-3766	125	5	sec	sec	PROPN
fnp-3766	125	6	period	period	NOUN
fnp-3766	125	7	the	the	DET
fnp-3766	125	8	tone	tone	NOUN
fnp-3766	125	9	was	be	AUX
fnp-3766	125	10	delivered	deliver	VERB
fnp-3766	125	11	and	and	CCONJ
fnp-3766	125	12	the	the	DET
fnp-3766	125	13	percent	percent	NOUN
fnp-3766	125	14	freezing	freezing	NOUN
fnp-3766	125	15	was	be	AUX
fnp-3766	125	16	recorded	record	VERB
fnp-3766	125	17	.	.	PUNCT
fnp-3766	126	1	no	no	DET
fnp-3766	126	2	shock	shock	NOUN
fnp-3766	126	3	was	be	AUX
fnp-3766	126	4	applied	apply	VERB
fnp-3766	126	5	during	during	ADP
fnp-3766	126	6	context	context	NOUN
fnp-3766	126	7	or	or	CCONJ
fnp-3766	126	8	tone	tone	NOUN
fnp-3766	126	9	session	session	NOUN
fnp-3766	126	10	on	on	ADP
fnp-3766	126	11	days	day	NOUN
fnp-3766	126	12	3	3	NUM
fnp-3766	126	13	and	and	CCONJ
fnp-3766	126	14	4	4	NUM
fnp-3766	126	15	.	.	NOUN
fnp-3766	126	16	results	result	VERB
fnp-3766	126	17	characterization	characterization	NOUN
fnp-3766	126	18	of	of	ADP
fnp-3766	126	19	ad	ad	NOUN
fnp-3766	126	20	/	/	SYM
fnp-3766	126	21	lbd	lbd	PROPN
fnp-3766	126	22	,	,	PUNCT
fnp-3766	126	23	ad	ad	NOUN
fnp-3766	126	24	,	,	PUNCT
fnp-3766	126	25	pa	pa	PROPN
fnp-3766	126	26	,	,	PUNCT
fnp-3766	126	27	and	and	CCONJ
fnp-3766	126	28	ndc	ndc	NOUN
fnp-3766	126	29	cases	case	NOUN
fnp-3766	126	30	in	in	ADP
fnp-3766	126	31	this	this	DET
fnp-3766	126	32	study	study	NOUN
fnp-3766	126	33	,	,	PUNCT
fnp-3766	126	34	we	we	PRON
fnp-3766	126	35	selected	select	VERB
fnp-3766	126	36	a	a	DET
fnp-3766	126	37	subset	subset	NOUN
fnp-3766	126	38	of	of	ADP
fnp-3766	126	39	ad	ad	NOUN
fnp-3766	126	40	,	,	PUNCT
fnp-3766	126	41	pa	pa	PROPN
fnp-3766	126	42	,	,	PUNCT
fnp-3766	126	43	and	and	CCONJ
fnp-3766	126	44	ndc	ndc	NOUN
fnp-3766	126	45	donors	donor	NOUN
fnp-3766	126	46	that	that	PRON
fnp-3766	126	47	were	be	AUX
fnp-3766	126	48	previously	previously	ADV
fnp-3766	126	49	analyzed	analyze	VERB
fnp-3766	126	50	(	(	PUNCT
fnp-3766	126	51	25	25	NUM
fnp-3766	126	52	)	)	PUNCT
fnp-3766	126	53	for	for	ADP
fnp-3766	126	54	examination	examination	NOUN
fnp-3766	126	55	of	of	ADP
fnp-3766	126	56	seeding	seed	VERB
fnp-3766	126	57	activity	activity	NOUN
fnp-3766	126	58	in	in	ADP
fnp-3766	126	59	app	app	PROPN
fnp-3766	126	60	,	,	PUNCT
fnp-3766	126	61	app	app	PROPN
fnp-3766	126	62	/	/	SYM
fnp-3766	126	63	tau	tau	PROPN
fnp-3766	126	64	,	,	PUNCT
fnp-3766	126	65	and	and	CCONJ
fnp-3766	126	66	tau	tau	PROPN
fnp-3766	126	67	transgenic	transgenic	NOUN
fnp-3766	126	68	mice	mouse	NOUN
fnp-3766	126	69	(	(	PUNCT
fnp-3766	126	70	table	table	NOUN
fnp-3766	126	71	1	1	NUM
fnp-3766	126	72	,	,	PUNCT
fnp-3766	126	73	ad	ad	NOUN
fnp-3766	126	74	1	1	NUM
fnp-3766	126	75	and	and	CCONJ
fnp-3766	126	76	2	2	NUM
fnp-3766	126	77	,	,	PUNCT
fnp-3766	126	78	pa	pa	PROPN
fnp-3766	126	79	1	1	NUM
fnp-3766	126	80	,	,	PUNCT
fnp-3766	126	81	2	2	NUM
fnp-3766	126	82	,	,	PUNCT
fnp-3766	126	83	3	3	NUM
fnp-3766	126	84	,	,	PUNCT
fnp-3766	126	85	4	4	NUM
fnp-3766	126	86	,	,	PUNCT
fnp-3766	126	87	and	and	CCONJ
fnp-3766	126	88	ndc	ndc	PROPN
fnp-3766	126	89	1	1	NUM
fnp-3766	126	90	and	and	CCONJ
fnp-3766	126	91	2	2	NUM
fnp-3766	126	92	)	)	PUNCT
fnp-3766	126	93	.	.	PUNCT
fnp-3766	127	1	all	all	DET
fnp-3766	127	2	8	8	NUM
fnp-3766	127	3	of	of	ADP
fnp-3766	127	4	these	these	DET
fnp-3766	127	5	donors	donor	NOUN
fnp-3766	127	6	exhibited	exhibit	VERB
fnp-3766	127	7	some	some	DET
fnp-3766	127	8	degree	degree	NOUN
fnp-3766	127	9	of	of	ADP
fnp-3766	127	10	lewy	lewy	ADJ
fnp-3766	127	11	body	body	NOUN
fnp-3766	127	12	pathology	pathology	NOUN
fnp-3766	127	13	(	(	PUNCT
fnp-3766	127	14	lbd	lbd	PROPN
fnp-3766	127	15	)	)	PUNCT
fnp-3766	127	16	.	.	PUNCT
fnp-3766	128	1	two	two	NUM
fnp-3766	128	2	of	of	ADP
fnp-3766	128	3	the	the	DET
fnp-3766	128	4	donors	donor	NOUN
fnp-3766	128	5	selected	select	VERB
fnp-3766	128	6	for	for	ADP
fnp-3766	128	7	the	the	DET
fnp-3766	128	8	study	study	NOUN
fnp-3766	128	9	were	be	AUX
fnp-3766	128	10	sub	sub	ADJ
fnp-3766	128	11	-	-	VERB
fnp-3766	128	12	categorized	categorize	VERB
fnp-3766	128	13	with	with	ADP
fnp-3766	128	14	cerebral	cerebral	ADJ
fnp-3766	128	15	amyloid	amyloid	NOUN
fnp-3766	128	16	angiopathy	angiopathy	ADJ
fnp-3766	128	17	(	(	PUNCT
fnp-3766	128	18	caa	caa	NOUN
fnp-3766	128	19	)	)	PUNCT
fnp-3766	128	20	;	;	PUNCT
fnp-3766	128	21	pa	pa	PROPN
fnp-3766	128	22	3	3	NUM
fnp-3766	128	23	had	have	VERB
fnp-3766	128	24	a	a	DET
fnp-3766	128	25	high	high	ADJ
fnp-3766	128	26	abundance	abundance	NOUN
fnp-3766	128	27	of	of	ADP
fnp-3766	128	28	vascular	vascular	ADJ
fnp-3766	128	29	amyloid	amyloid	NOUN
fnp-3766	128	30	with	with	ADP
fnp-3766	128	31	a	a	DET
fnp-3766	128	32	caa	caa	NOUN
fnp-3766	128	33	score	score	NOUN
fnp-3766	128	34	of	of	ADP
fnp-3766	128	35	2	2	NUM
fnp-3766	128	36	+	+	NOUN
fnp-3766	128	37	-3	-3	ADJ
fnp-3766	128	38	+	+	NOUN
fnp-3766	128	39	while	while	SCONJ
fnp-3766	128	40	ad	ad	NOUN
fnp-3766	128	41	1	1	NUM
fnp-3766	128	42	had	have	VERB
fnp-3766	128	43	moderate	moderate	ADJ
fnp-3766	128	44	levels	level	NOUN
fnp-3766	128	45	of	of	ADP
fnp-3766	128	46	vascular	vascular	NOUN
fnp-3766	129	1	aβ	aβ	NOUN
fnp-3766	129	2	deposition	deposition	NOUN
fnp-3766	129	3	with	with	ADP
fnp-3766	129	4	a	a	DET
fnp-3766	129	5	score	score	NOUN
fnp-3766	129	6	of	of	ADP
fnp-3766	129	7	1	1	NUM
fnp-3766	129	8	+	+	CCONJ
fnp-3766	129	9	(	(	PUNCT
fnp-3766	129	10	table	table	NOUN
fnp-3766	129	11	1	1	NUM
fnp-3766	129	12	)	)	PUNCT
fnp-3766	129	13	.	.	PUNCT
fnp-3766	130	1	as	as	SCONJ
fnp-3766	130	2	expected	expect	VERB
fnp-3766	130	3	,	,	PUNCT
fnp-3766	130	4	the	the	DET
fnp-3766	130	5	two	two	NUM
fnp-3766	130	6	ad	ad	NOUN
fnp-3766	130	7	brains	brain	NOUN
fnp-3766	130	8	had	have	VERB
fnp-3766	130	9	significant	significant	ADJ
fnp-3766	130	10	accumulation	accumulation	NOUN
fnp-3766	130	11	of	of	ADP
fnp-3766	130	12	tau	tau	PROPN
fnp-3766	130	13	,	,	PUNCT
fnp-3766	130	14	indicated	indicate	VERB
fnp-3766	130	15	by	by	ADP
fnp-3766	130	16	braak	braak	NOUN
fnp-3766	130	17	staging	staging	NOUN
fnp-3766	130	18	(	(	PUNCT
fnp-3766	130	19	5.5	5.5	NUM
fnp-3766	130	20	and	and	CCONJ
fnp-3766	130	21	6	6	NUM
fnp-3766	130	22	)	)	PUNCT
fnp-3766	130	23	(	(	PUNCT
fnp-3766	130	24	table	table	NOUN
fnp-3766	130	25	1	1	NUM
fnp-3766	130	26	)	)	PUNCT
fnp-3766	130	27	.	.	PUNCT
fnp-3766	131	1	the	the	DET
fnp-3766	131	2	pa	pa	PROPN
fnp-3766	131	3	and	and	CCONJ
fnp-3766	131	4	ndc	ndc	PROPN
fnp-3766	131	5	brains	brain	NOUN
fnp-3766	131	6	had	have	VERB
fnp-3766	131	7	lower	low	ADJ
fnp-3766	131	8	abundance	abundance	NOUN
fnp-3766	131	9	of	of	ADP
fnp-3766	131	10	tau	tau	PROPN
fnp-3766	131	11	than	than	ADP
fnp-3766	131	12	the	the	DET
fnp-3766	131	13	ad	ad	NOUN
fnp-3766	131	14	brains	brain	NOUN
fnp-3766	131	15	,	,	PUNCT
fnp-3766	131	16	but	but	CCONJ
fnp-3766	131	17	were	be	AUX
fnp-3766	131	18	similar	similar	ADJ
fnp-3766	131	19	to	to	ADP
fnp-3766	131	20	each	each	DET
fnp-3766	131	21	other	other	ADJ
fnp-3766	131	22	(	(	PUNCT
fnp-3766	131	23	2	2	NUM
fnp-3766	131	24	,	,	PUNCT
fnp-3766	131	25	2.5	2.5	NUM
fnp-3766	131	26	,	,	PUNCT
fnp-3766	131	27	3	3	NUM
fnp-3766	131	28	,	,	PUNCT
fnp-3766	131	29	2	2	NUM
fnp-3766	131	30	,	,	PUNCT
fnp-3766	131	31	and	and	CCONJ
fnp-3766	131	32	2	2	NUM
fnp-3766	131	33	,	,	PUNCT
fnp-3766	131	34	3	3	NUM
fnp-3766	131	35	,	,	PUNCT
fnp-3766	131	36	respectively	respectively	ADV
fnp-3766	131	37	)	)	PUNCT
fnp-3766	131	38	(	(	PUNCT
fnp-3766	131	39	table	table	NOUN
fnp-3766	131	40	1	1	NUM
fnp-3766	131	41	)	)	PUNCT
fnp-3766	131	42	.	.	PUNCT
fnp-3766	132	1	in	in	ADP
fnp-3766	132	2	this	this	DET
fnp-3766	132	3	set	set	NOUN
fnp-3766	132	4	of	of	ADP
fnp-3766	132	5	cases	case	NOUN
fnp-3766	132	6	,	,	PUNCT
fnp-3766	132	7	all	all	PRON
fnp-3766	132	8	also	also	ADV
fnp-3766	132	9	exhibited	exhibit	VERB
fnp-3766	132	10	incidental	incidental	ADJ
fnp-3766	132	11	,	,	PUNCT
fnp-3766	132	12	diffuse	diffuse	NOUN
fnp-3766	132	13	,	,	PUNCT
fnp-3766	132	14	αsyn	αsyn	ADJ
fnp-3766	132	15	pathology	pathology	NOUN
fnp-3766	132	16	.	.	PUNCT
fnp-3766	133	1	to	to	ADP
fnp-3766	133	2	these	these	DET
fnp-3766	133	3	8	8	NUM
fnp-3766	133	4	,	,	PUNCT
fnp-3766	133	5	we	we	PRON
fnp-3766	133	6	added	add	VERB
fnp-3766	133	7	6	6	NUM
fnp-3766	133	8	additional	additional	ADJ
fnp-3766	133	9	donors	donor	NOUN
fnp-3766	133	10	that	that	PRON
fnp-3766	133	11	included	include	VERB
fnp-3766	133	12	two	two	NUM
fnp-3766	133	13	ad	ad	NOUN
fnp-3766	133	14	(	(	PUNCT
fnp-3766	133	15	no	no	DET
fnp-3766	133	16	lbd	lbd	PROPN
fnp-3766	133	17	)	)	PUNCT
fnp-3766	133	18	,	,	PUNCT
fnp-3766	133	19	two	two	NUM
fnp-3766	133	20	with	with	ADP
fnp-3766	133	21	lewy	lewy	ADJ
fnp-3766	133	22	-	-	PUNCT
fnp-3766	133	23	body	body	NOUN
fnp-3766	133	24	variant	variant	NOUN
fnp-3766	133	25	ad	ad	NOUN
fnp-3766	133	26	(	(	PUNCT
fnp-3766	133	27	ad	ad	NOUN
fnp-3766	133	28	/	/	SYM
fnp-3766	133	29	lbd	lbd	PROPN
fnp-3766	133	30	)	)	PUNCT
fnp-3766	133	31	,	,	PUNCT
fnp-3766	133	32	and	and	CCONJ
fnp-3766	133	33	2	2	NUM
fnp-3766	133	34	additional	additional	ADJ
fnp-3766	133	35	controls	control	NOUN
fnp-3766	133	36	that	that	PRON
fnp-3766	133	37	were	be	AUX
fnp-3766	133	38	free	free	ADJ
fnp-3766	133	39	of	of	ADP
fnp-3766	133	40	all	all	DET
fnp-3766	133	41	types	type	NOUN
fnp-3766	133	42	of	of	ADP
fnp-3766	133	43	pathology	pathology	NOUN
fnp-3766	133	44	(	(	PUNCT
fnp-3766	133	45	table	table	NOUN
fnp-3766	133	46	1	1	NUM
fnp-3766	133	47	,	,	PUNCT
fnp-3766	133	48	ad	ad	NOUN
fnp-3766	133	49	3	3	NUM
fnp-3766	133	50	and	and	CCONJ
fnp-3766	133	51	4	4	NUM
fnp-3766	133	52	,	,	PUNCT
fnp-3766	133	53	ad	ad	NOUN
fnp-3766	133	54	/	/	SYM
fnp-3766	133	55	lbd	lbd	PROPN
fnp-3766	133	56	1	1	NUM
fnp-3766	133	57	and	and	CCONJ
fnp-3766	133	58	2	2	NUM
fnp-3766	133	59	,	,	PUNCT
fnp-3766	133	60	and	and	CCONJ
fnp-3766	133	61	ndc	ndc	PROPN
fnp-3766	133	62	3	3	NUM
fnp-3766	133	63	and	and	CCONJ
fnp-3766	133	64	4	4	NUM
fnp-3766	133	65	)	)	PUNCT
fnp-3766	133	66	.	.	PUNCT
fnp-3766	134	1	these	these	DET
fnp-3766	134	2	brains	brain	NOUN
fnp-3766	134	3	were	be	AUX
fnp-3766	134	4	used	use	VERB
fnp-3766	134	5	in	in	ADP
fnp-3766	134	6	seeding	seed	VERB
fnp-3766	134	7	app	app	NOUN
fnp-3766	134	8	,	,	PUNCT
fnp-3766	134	9	app	app	PROPN
fnp-3766	134	10	/	/	SYM
fnp-3766	134	11	α	α	NOUN
fnp-3766	134	12	-	-	PUNCT
fnp-3766	134	13	synuclein	synuclein	NOUN
fnp-3766	134	14	(	(	PUNCT
fnp-3766	134	15	αsyn	αsyn	PROPN
fnp-3766	134	16	)	)	PUNCT
fnp-3766	134	17	,	,	PUNCT
fnp-3766	134	18	and	and	CCONJ
fnp-3766	134	19	αsyn	αsyn	ADJ
fnp-3766	134	20	mice	mouse	NOUN
fnp-3766	134	21	so	so	SCONJ
fnp-3766	134	22	that	that	SCONJ
fnp-3766	134	23	we	we	PRON
fnp-3766	134	24	would	would	AUX
fnp-3766	134	25	be	be	AUX
fnp-3766	134	26	able	able	ADJ
fnp-3766	134	27	to	to	PART
fnp-3766	134	28	compare	compare	VERB
fnp-3766	134	29	ad	ad	NOUN
fnp-3766	134	30	and	and	CCONJ
fnp-3766	134	31	ndc	ndc	NOUN
fnp-3766	134	32	that	that	PRON
fnp-3766	134	33	lacked	lack	VERB
fnp-3766	134	34	αsyn	αsyn	ADJ
fnp-3766	134	35	pathology	pathology	NOUN
fnp-3766	134	36	to	to	ADP
fnp-3766	134	37	ad	ad	NOUN
fnp-3766	134	38	/	/	SYM
fnp-3766	134	39	lbd	lbd	NOUN
fnp-3766	134	40	brains	brain	NOUN
fnp-3766	134	41	with	with	ADP
fnp-3766	134	42	high	high	ADJ
fnp-3766	134	43	levels	level	NOUN
fnp-3766	134	44	of	of	ADP
fnp-3766	134	45	αsyn	αsyn	PROPN
fnp-3766	134	46	pathology	pathology	NOUN
fnp-3766	134	47	.	.	PUNCT
fnp-3766	135	1	to	to	PART
fnp-3766	135	2	characterize	characterize	VERB
fnp-3766	135	3	the	the	DET
fnp-3766	135	4	pathology	pathology	NOUN
fnp-3766	135	5	in	in	ADP
fnp-3766	135	6	the	the	DET
fnp-3766	135	7	ad	ad	NOUN
fnp-3766	135	8	and	and	CCONJ
fnp-3766	135	9	pa	pa	PROPN
fnp-3766	135	10	brains	brain	NOUN
fnp-3766	135	11	used	use	VERB
fnp-3766	135	12	to	to	PART
fnp-3766	135	13	seed	seed	VERB
fnp-3766	135	14	the	the	DET
fnp-3766	135	15	app	app	PROPN
fnp-3766	135	16	/	/	SYM
fnp-3766	135	17	tau	tau	PROPN
fnp-3766	135	18	,	,	PUNCT
fnp-3766	135	19	app	app	PROPN
fnp-3766	135	20	,	,	PUNCT
fnp-3766	135	21	and	and	CCONJ
fnp-3766	135	22	tau	tau	PROPN
fnp-3766	135	23	mice	mouse	NOUN
fnp-3766	135	24	,	,	PUNCT
fnp-3766	135	25	sections	section	NOUN
fnp-3766	135	26	were	be	AUX
fnp-3766	135	27	stained	stain	VERB
fnp-3766	135	28	with	with	ADP
fnp-3766	135	29	a	a	DET
fnp-3766	135	30	pan	pan	ADJ
fnp-3766	135	31	-	-	ADJ
fnp-3766	135	32	aβ	aβ	ADJ
fnp-3766	135	33	antibody	antibody	NOUN
fnp-3766	135	34	(	(	PUNCT
fnp-3766	135	35	fig	fig	NOUN
fnp-3766	135	36	.	.	PUNCT
fnp-3766	136	1	s1a	s1a	NOUN
fnp-3766	136	2	)	)	PUNCT
fnp-3766	137	1	,	,	PUNCT
fnp-3766	137	2	thioflavin	thioflavin	PROPN
fnp-3766	137	3	s	s	PART
fnp-3766	137	4	(	(	PUNCT
fnp-3766	137	5	thio	thio	NOUN
fnp-3766	137	6	-	-	PUNCT
fnp-3766	137	7	s	s	NOUN
fnp-3766	137	8	)	)	PUNCT
fnp-3766	137	9	(	(	PUNCT
fnp-3766	137	10	fig	fig	NOUN
fnp-3766	137	11	.	.	PUNCT
fnp-3766	138	1	s1b	s1b	NOUN
fnp-3766	138	2	)	)	PUNCT
fnp-3766	138	3	,	,	PUNCT
fnp-3766	138	4	and	and	CCONJ
fnp-3766	138	5	with	with	ADP
fnp-3766	138	6	a	a	DET
fnp-3766	138	7	phospho	phospho	ADJ
fnp-3766	138	8	-	-	PUNCT
fnp-3766	138	9	specific	specific	ADJ
fnp-3766	138	10	tau	tau	NOUN
fnp-3766	138	11	antibody	antibody	NOUN
fnp-3766	138	12	(	(	PUNCT
fnp-3766	138	13	fig	fig	NOUN
fnp-3766	138	14	.	.	PUNCT
fnp-3766	139	1	s1c	s1c	NOUN
fnp-3766	139	2	)	)	PUNCT
fnp-3766	139	3	.	.	PUNCT
fnp-3766	140	1	we	we	PRON
fnp-3766	140	2	observed	observe	VERB
fnp-3766	140	3	widespread	widespread	ADJ
fnp-3766	140	4	aβ	aβ	NOUN
fnp-3766	140	5	deposition	deposition	NOUN
fnp-3766	140	6	of	of	ADP
fnp-3766	140	7	both	both	CCONJ
fnp-3766	140	8	diffuse	diffuse	ADJ
fnp-3766	140	9	and	and	CCONJ
fnp-3766	140	10	compact	compact	ADJ
fnp-3766	140	11	amyloid	amyloid	NOUN
fnp-3766	140	12	in	in	ADP
fnp-3766	140	13	both	both	DET
fnp-3766	140	14	ad	ad	NOUN
fnp-3766	140	15	and	and	CCONJ
fnp-3766	140	16	pa	pa	PROPN
fnp-3766	140	17	(	(	PUNCT
fnp-3766	140	18	fig	fig	NOUN
fnp-3766	140	19	.	.	PUNCT
fnp-3766	141	1	s1a	s1a	PROPN
fnp-3766	141	2	,	,	PUNCT
fnp-3766	141	3	b	b	NOUN
fnp-3766	141	4	)	)	PUNCT
fnp-3766	141	5	,	,	PUNCT
fnp-3766	141	6	with	with	ADP
fnp-3766	141	7	a	a	DET
fnp-3766	141	8	subset	subset	NOUN
fnp-3766	141	9	showing	show	VERB
fnp-3766	141	10	striking	striking	ADJ
fnp-3766	141	11	caa	caa	NOUN
fnp-3766	141	12	.	.	PUNCT
fnp-3766	142	1	pa	pa	PROPN
fnp-3766	142	2	3	3	NUM
fnp-3766	142	3	had	have	VERB
fnp-3766	142	4	numerous	numerous	ADJ
fnp-3766	142	5	,	,	PUNCT
fnp-3766	142	6	thio	thio	NOUN
fnp-3766	142	7	-	-	PUNCT
fnp-3766	142	8	s	s	NOUN
fnp-3766	142	9	positive	positive	ADJ
fnp-3766	142	10	,	,	PUNCT
fnp-3766	142	11	vascular	vascular	ADJ
fnp-3766	142	12	amyloid	amyloid	NOUN
fnp-3766	142	13	deposits	deposit	NOUN
fnp-3766	142	14	,	,	PUNCT
fnp-3766	142	15	consistent	consistent	ADJ
fnp-3766	142	16	with	with	ADP
fnp-3766	142	17	the	the	DET
fnp-3766	142	18	assessment	assessment	NOUN
fnp-3766	142	19	of	of	ADP
fnp-3766	142	20	caa	caa	NOUN
fnp-3766	142	21	as	as	ADP
fnp-3766	142	22	2	2	NUM
fnp-3766	142	23	+	+	NOUN
fnp-3766	142	24	-3	-3	ADJ
fnp-3766	142	25	+	+	CCONJ
fnp-3766	142	26	(	(	PUNCT
fnp-3766	142	27	fig	fig	NOUN
fnp-3766	142	28	.	.	PUNCT
fnp-3766	143	1	s1a	s1a	PROPN
fnp-3766	143	2	,	,	PUNCT
fnp-3766	143	3	b	b	NOUN
fnp-3766	143	4	)	)	PUNCT
fnp-3766	143	5	.	.	PUNCT
fnp-3766	144	1	similarly	similarly	ADV
fnp-3766	144	2	,	,	PUNCT
fnp-3766	144	3	we	we	PRON
fnp-3766	144	4	observed	observe	VERB
fnp-3766	144	5	thio	thio	NOUN
fnp-3766	144	6	-	-	PUNCT
fnp-3766	144	7	s	s	PART
fnp-3766	144	8	positive	positive	ADJ
fnp-3766	144	9	amyloid	amyloid	NOUN
fnp-3766	144	10	staining	stain	VERB
fnp-3766	144	11	surrounding	surround	VERB
fnp-3766	144	12	several	several	ADJ
fnp-3766	144	13	vessels	vessel	NOUN
fnp-3766	144	14	within	within	ADP
fnp-3766	144	15	ad	ad	NOUN
fnp-3766	144	16	1	1	NUM
fnp-3766	144	17	,	,	PUNCT
fnp-3766	144	18	consistent	consistent	ADJ
fnp-3766	144	19	with	with	ADP
fnp-3766	144	20	a	a	DET
fnp-3766	144	21	caa	caa	NOUN
fnp-3766	144	22	score	score	NOUN
fnp-3766	144	23	of	of	ADP
fnp-3766	144	24	1	1	NUM
fnp-3766	144	25	+	+	CCONJ
fnp-3766	144	26	(	(	PUNCT
fnp-3766	144	27	fig	fig	NOUN
fnp-3766	144	28	.	.	PUNCT
fnp-3766	145	1	s1a	s1a	PROPN
fnp-3766	145	2	,	,	PUNCT
fnp-3766	145	3	b	b	NOUN
fnp-3766	145	4	)	)	PUNCT
fnp-3766	145	5	.	.	PUNCT
fnp-3766	146	1	ad	ad	NOUN
fnp-3766	146	2	2	2	NUM
fnp-3766	146	3	contained	contain	VERB
fnp-3766	146	4	several	several	ADJ
fnp-3766	146	5	cored	core	VERB
fnp-3766	146	6	thio	thio	NOUN
fnp-3766	146	7	-	-	PUNCT
fnp-3766	146	8	s	s	VERB
fnp-3766	146	9	positive	positive	ADJ
fnp-3766	146	10	deposits	deposit	NOUN
fnp-3766	146	11	while	while	SCONJ
fnp-3766	146	12	the	the	DET
fnp-3766	146	13	compact	compact	ADJ
fnp-3766	146	14	deposits	deposit	NOUN
fnp-3766	146	15	in	in	ADP
fnp-3766	146	16	pa	pa	PROPN
fnp-3766	146	17	1	1	NUM
fnp-3766	146	18	,	,	PUNCT
fnp-3766	146	19	2	2	NUM
fnp-3766	146	20	,	,	PUNCT
fnp-3766	146	21	and	and	CCONJ
fnp-3766	146	22	4	4	NUM
fnp-3766	146	23	had	have	VERB
fnp-3766	146	24	little	little	ADJ
fnp-3766	146	25	to	to	ADP
fnp-3766	146	26	no	no	DET
fnp-3766	146	27	thio	thio	NOUN
fnp-3766	146	28	-	-	PUNCT
fnp-3766	146	29	s	s	NOUN
fnp-3766	146	30	staining	stain	VERB
fnp-3766	146	31	.	.	PUNCT
fnp-3766	147	1	as	as	SCONJ
fnp-3766	147	2	expected	expect	VERB
fnp-3766	147	3	,	,	PUNCT
fnp-3766	147	4	ad	ad	NOUN
fnp-3766	147	5	1	1	NUM
fnp-3766	147	6	and	and	CCONJ
fnp-3766	147	7	2	2	NUM
fnp-3766	147	8	contained	contain	VERB
fnp-3766	147	9	both	both	CCONJ
fnp-3766	147	10	substantial	substantial	ADJ
fnp-3766	147	11	phosphorylated	phosphorylate	VERB
fnp-3766	147	12	tau	tau	NOUN
fnp-3766	147	13	in	in	ADP
fnp-3766	147	14	form	form	NOUN
fnp-3766	147	15	of	of	ADP
fnp-3766	147	16	dystrophic	dystrophic	ADJ
fnp-3766	147	17	neurites	neurite	NOUN
fnp-3766	147	18	,	,	PUNCT
fnp-3766	147	19	neuropil	neuropil	NOUN
fnp-3766	147	20	threads	thread	NOUN
fnp-3766	147	21	and	and	CCONJ
fnp-3766	147	22	neuronal	neuronal	ADJ
fnp-3766	147	23	inclusions	inclusion	NOUN
fnp-3766	147	24	while	while	SCONJ
fnp-3766	147	25	all	all	DET
fnp-3766	147	26	four	four	NUM
fnp-3766	147	27	of	of	ADP
fnp-3766	147	28	the	the	DET
fnp-3766	147	29	pa	pa	PROPN
fnp-3766	147	30	were	be	AUX
fnp-3766	147	31	negative	negative	ADJ
fnp-3766	147	32	for	for	ADP
fnp-3766	147	33	tau	tau	PROPN
fnp-3766	147	34	deposits	deposit	NOUN
fnp-3766	147	35	(	(	PUNCT
fnp-3766	147	36	fig	fig	NOUN
fnp-3766	147	37	.	.	PUNCT
fnp-3766	147	38	s1c	s1c	NOUN
fnp-3766	147	39	)	)	PUNCT
fnp-3766	147	40	.	.	PUNCT
fnp-3766	148	1	ndc	ndc	PROPN
fnp-3766	148	2	1	1	NUM
fnp-3766	148	3	and	and	CCONJ
fnp-3766	148	4	2	2	NUM
fnp-3766	148	5	were	be	AUX
fnp-3766	148	6	negative	negative	ADJ
fnp-3766	148	7	for	for	ADP
fnp-3766	148	8	aβ	aβ	PRON
fnp-3766	148	9	and	and	CCONJ
fnp-3766	148	10	tau	tau	PROPN
fnp-3766	148	11	deposits	deposit	NOUN
fnp-3766	148	12	by	by	ADP
fnp-3766	148	13	both	both	DET
fnp-3766	148	14	immunostaining	immunostaining	NOUN
fnp-3766	148	15	and	and	CCONJ
fnp-3766	148	16	thio	thio	NOUN
fnp-3766	148	17	-	-	PUNCT
fnp-3766	148	18	s	s	NOUN
fnp-3766	148	19	staining	stain	VERB
fnp-3766	148	20	.	.	PUNCT
fnp-3766	149	1	cerebral	cerebral	ADJ
fnp-3766	149	2	injection	injection	NOUN
fnp-3766	149	3	of	of	ADP
fnp-3766	149	4	brain	brain	NOUN
fnp-3766	149	5	lysates	lysate	NOUN
fnp-3766	149	6	into	into	ADP
fnp-3766	149	7	newborn	newborn	ADJ
fnp-3766	149	8	app	app	PROPN
fnp-3766	149	9	/	/	SYM
fnp-3766	149	10	tau	tau	PROPN
fnp-3766	149	11	and	and	CCONJ
fnp-3766	149	12	app	app	NOUN
fnp-3766	149	13	mice	mouse	NOUN
fnp-3766	149	14	results	result	NOUN
fnp-3766	149	15	in	in	ADP
fnp-3766	149	16	widespread	widespread	ADJ
fnp-3766	149	17	,	,	PUNCT
fnp-3766	149	18	robust	robust	ADJ
fnp-3766	149	19	amyloid	amyloid	NOUN
fnp-3766	149	20	deposition	deposition	NOUN
fnp-3766	149	21	to	to	PART
fnp-3766	149	22	gain	gain	VERB
fnp-3766	149	23	a	a	DET
fnp-3766	149	24	better	well	ADJ
fnp-3766	149	25	understanding	understanding	NOUN
fnp-3766	149	26	of	of	ADP
fnp-3766	149	27	the	the	DET
fnp-3766	149	28	type	type	NOUN
fnp-3766	149	29	of	of	ADP
fnp-3766	149	30	aβ	aβ	DET
fnp-3766	149	31	pathology	pathology	NOUN
fnp-3766	149	32	that	that	PRON
fnp-3766	149	33	unseeded	unseede	VERB
fnp-3766	149	34	prp.appsi	prp.appsi	NUM
fnp-3766	149	35	mice	mouse	NOUN
fnp-3766	149	36	produce	produce	VERB
fnp-3766	149	37	,	,	PUNCT
fnp-3766	149	38	we	we	PRON
fnp-3766	149	39	harvested	harvest	VERB
fnp-3766	149	40	breeder	breeder	NOUN
fnp-3766	149	41	mice	mouse	NOUN
fnp-3766	149	42	at	at	ADP
fnp-3766	149	43	various	various	ADJ
fnp-3766	149	44	ages	age	NOUN
fnp-3766	149	45	to	to	PART
fnp-3766	149	46	assess	assess	VERB
fnp-3766	149	47	phenotypic	phenotypic	ADJ
fnp-3766	149	48	variation	variation	NOUN
fnp-3766	149	49	(	(	PUNCT
fnp-3766	149	50	fig	fig	NOUN
fnp-3766	149	51	.	.	PUNCT
fnp-3766	150	1	s2a	s2a	NOUN
fnp-3766	150	2	and	and	CCONJ
fnp-3766	150	3	b	b	X
fnp-3766	150	4	)	)	PUNCT
fnp-3766	150	5	(	(	PUNCT
fnp-3766	150	6	37	37	NUM
fnp-3766	150	7	)	)	PUNCT
fnp-3766	150	8	.	.	PUNCT
fnp-3766	151	1	at	at	ADP
fnp-3766	151	2	12	12	NUM
fnp-3766	151	3	months	month	NOUN
fnp-3766	151	4	of	of	ADP
fnp-3766	151	5	age	age	NOUN
fnp-3766	151	6	,	,	PUNCT
fnp-3766	151	7	when	when	SCONJ
fnp-3766	151	8	deposition	deposition	NOUN
fnp-3766	151	9	begins	begin	VERB
fnp-3766	151	10	to	to	PART
fnp-3766	151	11	occur	occur	VERB
fnp-3766	151	12	in	in	ADP
fnp-3766	151	13	the	the	DET
fnp-3766	151	14	brains	brain	NOUN
fnp-3766	151	15	of	of	ADP
fnp-3766	151	16	prp.appsi	prp.appsi	PROPN
fnp-3766	151	17	mice	mouse	NOUN
fnp-3766	151	18	,	,	PUNCT
fnp-3766	151	19	any	any	DET
fnp-3766	151	20	given	give	VERB
fnp-3766	151	21	section	section	NOUN
fnp-3766	151	22	through	through	ADP
fnp-3766	151	23	the	the	DET
fnp-3766	151	24	cortex	cortex	NOUN
fnp-3766	151	25	and	and	CCONJ
fnp-3766	151	26	hippocampus	hippocampus	NOUN
fnp-3766	151	27	may	may	AUX
fnp-3766	151	28	exhibit	exhibit	VERB
fnp-3766	151	29	1	1	NUM
fnp-3766	151	30	or	or	CCONJ
fnp-3766	151	31	2	2	NUM
fnp-3766	151	32	diffuse	diffuse	NOUN
fnp-3766	151	33	tufted	tufte	VERB
fnp-3766	151	34	deposits	deposit	NOUN
fnp-3766	151	35	and/or	and/or	CCONJ
fnp-3766	151	36	cored	core	VERB
fnp-3766	151	37	deposits	deposit	NOUN
fnp-3766	151	38	(	(	PUNCT
fnp-3766	151	39	score	score	VERB
fnp-3766	151	40	+	+	PROPN
fnp-3766	151	41	/-	/-	PUNCT
fnp-3766	151	42	)	)	PUNCT
fnp-3766	151	43	.	.	PUNCT
fnp-3766	152	1	at	at	ADP
fnp-3766	152	2	this	this	DET
fnp-3766	152	3	age	age	NOUN
fnp-3766	152	4	,	,	PUNCT
fnp-3766	152	5	aβ	aβ	PRON
fnp-3766	152	6	deposition	deposition	NOUN
fnp-3766	152	7	also	also	ADV
fnp-3766	152	8	begins	begin	VERB
fnp-3766	152	9	to	to	PART
fnp-3766	152	10	appear	appear	VERB
fnp-3766	152	11	in	in	ADP
fnp-3766	152	12	the	the	DET
fnp-3766	152	13	meninges	meninge	NOUN
fnp-3766	152	14	surrounding	surround	VERB
fnp-3766	152	15	the	the	DET
fnp-3766	152	16	cerebellum	cerebellum	NOUN
fnp-3766	152	17	(	(	PUNCT
fnp-3766	152	18	fig	fig	NOUN
fnp-3766	152	19	.	.	PUNCT
fnp-3766	152	20	s2a	s2a	NOUN
fnp-3766	152	21	)	)	PUNCT
fnp-3766	152	22	.	.	PUNCT
fnp-3766	153	1	approximately	approximately	ADV
fnp-3766	153	2	50	50	NUM
fnp-3766	153	3	%	%	NOUN
fnp-3766	153	4	of	of	ADP
fnp-3766	153	5	prp.appsi	prp.appsi	PROPN
fnp-3766	153	6	mice	mouse	NOUN
fnp-3766	153	7	at	at	ADP
fnp-3766	153	8	11	11	NUM
fnp-3766	153	9	-	-	SYM
fnp-3766	153	10	13	13	NUM
fnp-3766	153	11	months	month	NOUN
fnp-3766	153	12	of	of	ADP
fnp-3766	153	13	age	age	NOUN
fnp-3766	153	14	exhibit	exhibit	VERB
fnp-3766	153	15	no	no	DET
fnp-3766	153	16	aβ	aβ	NOUN
fnp-3766	153	17	pathology	pathology	NOUN
fnp-3766	153	18	or	or	CCONJ
fnp-3766	153	19	show	show	VERB
fnp-3766	153	20	only	only	ADJ
fnp-3766	153	21	meningeal	meningeal	ADJ
fnp-3766	153	22	deposition	deposition	NOUN
fnp-3766	153	23	in	in	ADP
fnp-3766	153	24	the	the	DET
fnp-3766	153	25	cerebellum	cerebellum	NOUN
fnp-3766	153	26	(	(	PUNCT
fnp-3766	153	27	fig	fig	NOUN
fnp-3766	153	28	.	.	PUNCT
fnp-3766	153	29	s2a	s2a	NOUN
fnp-3766	153	30	)	)	PUNCT
fnp-3766	153	31	.	.	PUNCT
fnp-3766	154	1	to	to	PART
fnp-3766	154	2	concurrently	concurrently	ADV
fnp-3766	154	3	examine	examine	VERB
fnp-3766	154	4	whether	whether	SCONJ
fnp-3766	154	5	tau	tau	PROPN
fnp-3766	154	6	pathology	pathology	NOUN
fnp-3766	154	7	could	could	AUX
fnp-3766	154	8	be	be	AUX
fnp-3766	154	9	augmented	augment	VERB
fnp-3766	154	10	by	by	ADP
fnp-3766	154	11	seeding	seed	VERB
fnp-3766	154	12	from	from	ADP
fnp-3766	154	13	these	these	DET
fnp-3766	154	14	lysates	lysate	NOUN
fnp-3766	154	15	,	,	PUNCT
fnp-3766	154	16	the	the	DET
fnp-3766	154	17	prp.appsi	prp.appsi	NUM
fnp-3766	154	18	mice	mouse	NOUN
fnp-3766	154	19	were	be	AUX
fnp-3766	154	20	crossed	cross	VERB
fnp-3766	154	21	to	to	ADP
fnp-3766	154	22	a	a	DET
fnp-3766	154	23	line	line	NOUN
fnp-3766	154	24	of	of	ADP
fnp-3766	154	25	mice	mouse	NOUN
fnp-3766	154	26	that	that	PRON
fnp-3766	154	27	express	express	VERB
fnp-3766	154	28	human	human	ADJ
fnp-3766	154	29	tau	tau	PROPN
fnp-3766	154	30	p301l	p301l	PROPN
fnp-3766	154	31	(	(	PUNCT
fnp-3766	154	32	itau	itau	NOUN
fnp-3766	154	33	-	-	PUNCT
fnp-3766	154	34	p301l	p301l	NOUN
fnp-3766	154	35	)	)	PUNCT
fnp-3766	154	36	(	(	PUNCT
fnp-3766	154	37	table	table	NOUN
fnp-3766	154	38	2	2	NUM
fnp-3766	154	39	)	)	PUNCT
fnp-3766	154	40	(	(	PUNCT
fnp-3766	154	41	38	38	NUM
fnp-3766	154	42	,	,	PUNCT
fnp-3766	154	43	47	47	NUM
fnp-3766	154	44	)	)	PUNCT
fnp-3766	154	45	.	.	PUNCT
fnp-3766	155	1	the	the	DET
fnp-3766	155	2	itau	itau	NOUN
fnp-3766	155	3	-	-	PUNCT
fnp-3766	155	4	p301l	p301l	NOUN
fnp-3766	155	5	mice	mouse	NOUN
fnp-3766	155	6	express	express	VERB
fnp-3766	155	7	mutant	mutant	ADJ
fnp-3766	155	8	human	human	ADJ
fnp-3766	155	9	tau	tau	PROPN
fnp-3766	155	10	at	at	ADP
fnp-3766	155	11	levels	level	NOUN
fnp-3766	155	12	2	2	NUM
fnp-3766	155	13	-	-	SYM
fnp-3766	155	14	3	3	NUM
fnp-3766	155	15	fold	fold	NOUN
fnp-3766	155	16	higher	high	ADJ
fnp-3766	155	17	than	than	ADP
fnp-3766	155	18	nontransgenic	nontransgenic	ADJ
fnp-3766	155	19	mice	mouse	NOUN
fnp-3766	155	20	(	(	PUNCT
fnp-3766	155	21	fig	fig	NOUN
fnp-3766	155	22	.	.	PUNCT
fnp-3766	156	1	s3	s3	NOUN
fnp-3766	156	2	)	)	PUNCT
fnp-3766	156	3	.	.	PUNCT
fnp-3766	157	1	to	to	PART
fnp-3766	157	2	compare	compare	VERB
fnp-3766	157	3	the	the	DET
fnp-3766	157	4	relative	relative	ADJ
fnp-3766	157	5	ability	ability	NOUN
fnp-3766	157	6	of	of	ADP
fnp-3766	157	7	homogenates	homogenate	NOUN
fnp-3766	157	8	prepared	prepare	VERB
fnp-3766	157	9	from	from	ADP
fnp-3766	157	10	ad	ad	NOUN
fnp-3766	157	11	and	and	CCONJ
fnp-3766	157	12	pa	pa	PROPN
fnp-3766	157	13	cases	case	NOUN
fnp-3766	157	14	to	to	PART
fnp-3766	157	15	seed	seed	VERB
fnp-3766	157	16	aβ	aβ	NOUN
fnp-3766	157	17	deposition	deposition	NOUN
fnp-3766	157	18	in	in	ADP
fnp-3766	157	19	these	these	DET
fnp-3766	157	20	mice	mouse	NOUN
fnp-3766	157	21	,	,	PUNCT
fnp-3766	157	22	lysates	lysate	NOUN
fnp-3766	157	23	from	from	ADP
fnp-3766	157	24	the	the	DET
fnp-3766	157	25	pre	pre	ADJ
fnp-3766	157	26	-	-	ADJ
fnp-3766	157	27	frontal	frontal	ADJ
fnp-3766	157	28	cortex	cortex	NOUN
fnp-3766	157	29	of	of	ADP
fnp-3766	157	30	the	the	DET
fnp-3766	157	31	ad	ad	NOUN
fnp-3766	157	32	,	,	PUNCT
fnp-3766	157	33	pa	pa	PROPN
fnp-3766	157	34	,	,	PUNCT
fnp-3766	157	35	and	and	CCONJ
fnp-3766	157	36	ndc	ndc	PROPN
fnp-3766	157	37	were	be	AUX
fnp-3766	157	38	injected	inject	VERB
fnp-3766	157	39	into	into	ADP
fnp-3766	157	40	the	the	DET
fnp-3766	157	41	cerebral	cerebral	ADJ
fnp-3766	157	42	ventricles	ventricle	NOUN
fnp-3766	157	43	of	of	ADP
fnp-3766	157	44	newborn	newborn	ADJ
fnp-3766	157	45	mice	mouse	NOUN
fnp-3766	157	46	at	at	ADP
fnp-3766	157	47	p0	p0	NOUN
fnp-3766	157	48	(	(	PUNCT
fnp-3766	157	49	31	31	NUM
fnp-3766	157	50	,	,	PUNCT
fnp-3766	157	51	42	42	NUM
fnp-3766	157	52	,	,	PUNCT
fnp-3766	157	53	43	43	NUM
fnp-3766	157	54	)	)	PUNCT
fnp-3766	157	55	.	.	PUNCT
fnp-3766	158	1	we	we	PRON
fnp-3766	158	2	confirmed	confirm	VERB
fnp-3766	158	3	that	that	SCONJ
fnp-3766	158	4	the	the	DET
fnp-3766	158	5	lysates	lysate	NOUN
fnp-3766	158	6	contained	contain	VERB
fnp-3766	158	7	aβ	aβ	NOUN
fnp-3766	158	8	by	by	ADP
fnp-3766	158	9	immunoblotting	immunoblotte	VERB
fnp-3766	158	10	and	and	CCONJ
fnp-3766	158	11	elisa	elisa	NOUN
fnp-3766	158	12	(	(	PUNCT
fnp-3766	158	13	fig	fig	NOUN
fnp-3766	158	14	.	.	PUNCT
fnp-3766	159	1	s1d	s1d	NOUN
fnp-3766	159	2	and	and	CCONJ
fnp-3766	159	3	table	table	NOUN
fnp-3766	159	4	1	1	NUM
fnp-3766	159	5	)	)	PUNCT
fnp-3766	159	6	.	.	PUNCT
fnp-3766	160	1	aβ	aβ	PRON
fnp-3766	160	2	was	be	AUX
fnp-3766	160	3	detectable	detectable	ADJ
fnp-3766	160	4	by	by	ADP
fnp-3766	160	5	immunoblot	immunoblot	NOUN
fnp-3766	160	6	in	in	ADP
fnp-3766	160	7	each	each	PRON
fnp-3766	160	8	of	of	ADP
fnp-3766	160	9	the	the	DET
fnp-3766	160	10	lysates	lysate	NOUN
fnp-3766	160	11	used	use	VERB
fnp-3766	160	12	for	for	ADP
fnp-3766	160	13	injection	injection	NOUN
fnp-3766	160	14	(	(	PUNCT
fnp-3766	160	15	fig	fig	NOUN
fnp-3766	160	16	.	.	PUNCT
fnp-3766	161	1	s1d	s1d	PROPN
fnp-3766	161	2	)	)	PUNCT
fnp-3766	161	3	,	,	PUNCT
fnp-3766	161	4	and	and	CCONJ
fnp-3766	161	5	enzyme	enzyme	NOUN
fnp-3766	161	6	-	-	PUNCT
fnp-3766	161	7	linked	link	VERB
fnp-3766	161	8	immunosorbent	immunosorbent	NOUN
fnp-3766	161	9	assay	assay	PROPN
fnp-3766	161	10	(	(	PUNCT
fnp-3766	161	11	elisa	elisa	NOUN
fnp-3766	161	12	)	)	PUNCT
fnp-3766	161	13	measurements	measurement	NOUN
fnp-3766	161	14	confirmed	confirm	VERB
fnp-3766	161	15	high	high	ADJ
fnp-3766	161	16	levels	level	NOUN
fnp-3766	161	17	of	of	ADP
fnp-3766	161	18	sds	sds	PROPN
fnp-3766	161	19	-	-	PUNCT
fnp-3766	161	20	soluble	soluble	ADJ
fnp-3766	161	21	and	and	CCONJ
fnp-3766	161	22	formic	formic	ADJ
fnp-3766	161	23	acid	acid	NOUN
fnp-3766	161	24	(	(	PUNCT
fnp-3766	161	25	fa	fa	NOUN
fnp-3766	161	26	)	)	PUNCT
fnp-3766	161	27	soluble	soluble	ADJ
fnp-3766	161	28	aβ42	aβ42	PROPN
fnp-3766	161	29	in	in	ADP
fnp-3766	161	30	each	each	DET
fnp-3766	161	31	brain	brain	NOUN
fnp-3766	161	32	lysate	lysate	NOUN
fnp-3766	161	33	(	(	PUNCT
fnp-3766	161	34	table	table	NOUN
fnp-3766	161	35	1	1	NUM
fnp-3766	161	36	)	)	PUNCT
fnp-3766	161	37	.	.	PUNCT
fnp-3766	162	1	we	we	PRON
fnp-3766	162	2	hypothesized	hypothesize	VERB
fnp-3766	162	3	that	that	SCONJ
fnp-3766	162	4	injection	injection	NOUN
fnp-3766	162	5	of	of	ADP
fnp-3766	162	6	these	these	DET
fnp-3766	162	7	lysates	lysate	NOUN
fnp-3766	162	8	in	in	ADP
fnp-3766	162	9	p0	p0	NOUN
fnp-3766	162	10	mice	mouse	NOUN
fnp-3766	162	11	would	would	AUX
fnp-3766	162	12	result	result	VERB
fnp-3766	162	13	in	in	ADP
fnp-3766	162	14	widespread	widespread	ADJ
fnp-3766	162	15	dispersion	dispersion	NOUN
fnp-3766	162	16	of	of	ADP
fnp-3766	162	17	the	the	DET
fnp-3766	162	18	aβ	aβ	NOUN
fnp-3766	162	19	or	or	CCONJ
fnp-3766	162	20	tau	tau	PROPN
fnp-3766	162	21	seeds	seed	NOUN
fnp-3766	162	22	,	,	PUNCT
fnp-3766	162	23	and	and	CCONJ
fnp-3766	162	24	potentially	potentially	ADV
fnp-3766	162	25	offer	offer	VERB
fnp-3766	162	26	the	the	DET
fnp-3766	162	27	best	good	ADJ
fnp-3766	162	28	chance	chance	NOUN
fnp-3766	162	29	to	to	PART
fnp-3766	162	30	extensively	extensively	ADV
fnp-3766	162	31	alter	alter	VERB
fnp-3766	162	32	the	the	DET
fnp-3766	162	33	type	type	NOUN
fnp-3766	162	34	of	of	ADP
fnp-3766	162	35	pathology	pathology	NOUN
fnp-3766	162	36	that	that	PRON
fnp-3766	162	37	would	would	AUX
fnp-3766	162	38	be	be	AUX
fnp-3766	162	39	induced	induce	VERB
fnp-3766	162	40	by	by	ADP
fnp-3766	162	41	seeding	seed	VERB
fnp-3766	162	42	.	.	PUNCT
fnp-3766	163	1	to	to	PART
fnp-3766	163	2	assess	assess	VERB
fnp-3766	163	3	amyloid	amyloid	NOUN
fnp-3766	163	4	pathology	pathology	NOUN
fnp-3766	163	5	,	,	PUNCT
fnp-3766	163	6	hemibrains	hemibrain	NOUN
fnp-3766	163	7	of	of	ADP
fnp-3766	163	8	seeded	seeded	ADJ
fnp-3766	163	9	mice	mouse	NOUN
fnp-3766	163	10	were	be	AUX
fnp-3766	163	11	stained	stain	VERB
fnp-3766	163	12	with	with	ADP
fnp-3766	163	13	a	a	DET
fnp-3766	163	14	pan	pan	ADJ
fnp-3766	163	15	-	-	ADJ
fnp-3766	163	16	aβ	aβ	ADJ
fnp-3766	163	17	antibody	antibody	NOUN
fnp-3766	163	18	and	and	CCONJ
fnp-3766	163	19	thio	thio	NOUN
fnp-3766	163	20	-	-	PUNCT
fnp-3766	163	21	s.	s.	PROPN
fnp-3766	163	22	in	in	ADP
fnp-3766	163	23	mice	mouse	NOUN
fnp-3766	163	24	injected	inject	VERB
fnp-3766	163	25	with	with	ADP
fnp-3766	163	26	either	either	CCONJ
fnp-3766	163	27	ad	ad	NOUN
fnp-3766	163	28	or	or	CCONJ
fnp-3766	163	29	pa	pa	PROPN
fnp-3766	163	30	lysates	lysate	NOUN
fnp-3766	163	31	,	,	PUNCT
fnp-3766	163	32	we	we	PRON
fnp-3766	163	33	observed	observe	VERB
fnp-3766	163	34	significant	significant	ADJ
fnp-3766	163	35	induction	induction	NOUN
fnp-3766	163	36	of	of	ADP
fnp-3766	163	37	aβ	aβ	PRON
fnp-3766	163	38	deposition	deposition	NOUN
fnp-3766	163	39	,	,	PUNCT
fnp-3766	163	40	comprised	comprise	VERB
fnp-3766	163	41	primarily	primarily	ADV
fnp-3766	163	42	of	of	ADP
fnp-3766	163	43	diffuse	diffuse	ADJ
fnp-3766	163	44	deposits	deposit	NOUN
fnp-3766	163	45	throughout	throughout	ADP
fnp-3766	163	46	the	the	DET
fnp-3766	163	47	cortex	cortex	NOUN
fnp-3766	163	48	and	and	CCONJ
fnp-3766	163	49	hippocampus	hippocampus	NOUN
fnp-3766	163	50	,	,	PUNCT
fnp-3766	163	51	with	with	ADP
fnp-3766	163	52	some	some	DET
fnp-3766	163	53	vascular	vascular	ADJ
fnp-3766	163	54	deposition	deposition	NOUN
fnp-3766	163	55	in	in	ADP
fnp-3766	163	56	the	the	DET
fnp-3766	163	57	pia	pia	NOUN
fnp-3766	163	58	surrounding	surround	VERB
fnp-3766	163	59	the	the	DET
fnp-3766	163	60	cortex	cortex	NOUN
fnp-3766	163	61	and	and	CCONJ
fnp-3766	163	62	within	within	ADP
fnp-3766	163	63	the	the	DET
fnp-3766	163	64	hippocampal	hippocampal	ADJ
fnp-3766	163	65	fissure	fissure	NOUN
fnp-3766	163	66	(	(	PUNCT
fnp-3766	163	67	fig	fig	NOUN
fnp-3766	163	68	.	.	PUNCT
fnp-3766	164	1	1b	1b	NUM
fnp-3766	164	2	,	,	PUNCT
fnp-3766	164	3	c	c	NOUN
fnp-3766	164	4	)	)	PUNCT
fnp-3766	164	5	.	.	PUNCT
fnp-3766	165	1	mice	mouse	NOUN
fnp-3766	165	2	injected	inject	VERB
fnp-3766	165	3	with	with	ADP
fnp-3766	165	4	homogenates	homogenate	NOUN
fnp-3766	165	5	from	from	ADP
fnp-3766	165	6	ndc	ndc	PROPN
fnp-3766	165	7	1	1	NUM
fnp-3766	165	8	and	and	CCONJ
fnp-3766	165	9	2	2	NUM
fnp-3766	165	10	,	,	PUNCT
fnp-3766	165	11	and	and	CCONJ
fnp-3766	165	12	mice	mouse	NOUN
fnp-3766	165	13	that	that	PRON
fnp-3766	165	14	were	be	AUX
fnp-3766	165	15	not	not	PART
fnp-3766	165	16	injected	inject	VERB
fnp-3766	165	17	,	,	PUNCT
fnp-3766	165	18	had	have	VERB
fnp-3766	165	19	little	little	ADJ
fnp-3766	165	20	aβ	aβ	PRON
fnp-3766	165	21	pathology	pathology	NOUN
fnp-3766	165	22	by	by	ADP
fnp-3766	165	23	12	12	NUM
fnp-3766	165	24	months	month	NOUN
fnp-3766	165	25	of	of	ADP
fnp-3766	165	26	age	age	NOUN
fnp-3766	165	27	(	(	PUNCT
fnp-3766	165	28	fig	fig	NOUN
fnp-3766	165	29	.	.	PUNCT
fnp-3766	166	1	1b	1b	NUM
fnp-3766	166	2	,	,	PUNCT
fnp-3766	166	3	c	c	NOUN
fnp-3766	166	4	)	)	PUNCT
fnp-3766	166	5	.	.	PUNCT
fnp-3766	167	1	examples	example	NOUN
fnp-3766	167	2	of	of	ADP
fnp-3766	167	3	cases	case	NOUN
fnp-3766	167	4	with	with	ADP
fnp-3766	167	5	the	the	DET
fnp-3766	167	6	most	most	ADV
fnp-3766	167	7	severe	severe	ADJ
fnp-3766	167	8	pathology	pathology	NOUN
fnp-3766	167	9	are	be	AUX
fnp-3766	167	10	shown	show	VERB
fnp-3766	167	11	in	in	ADP
fnp-3766	167	12	figure	figure	NOUN
fnp-3766	167	13	1	1	NUM
fnp-3766	167	14	,	,	PUNCT
fnp-3766	167	15	while	while	SCONJ
fnp-3766	167	16	images	image	NOUN
fnp-3766	167	17	of	of	ADP
fnp-3766	167	18	animals	animal	NOUN
fnp-3766	167	19	with	with	ADP
fnp-3766	167	20	the	the	DET
fnp-3766	167	21	least	least	ADJ
fnp-3766	167	22	pathology	pathology	NOUN
fnp-3766	167	23	are	be	AUX
fnp-3766	167	24	shown	show	VERB
fnp-3766	167	25	in	in	ADP
fnp-3766	167	26	figure	figure	NOUN
fnp-3766	167	27	s4	s4	PROPN
fnp-3766	167	28	.	.	PUNCT
fnp-3766	168	1	in	in	ADP
fnp-3766	168	2	all	all	DET
fnp-3766	168	3	cases	case	NOUN
fnp-3766	168	4	,	,	PUNCT
fnp-3766	168	5	however	however	ADV
fnp-3766	168	6	,	,	PUNCT
fnp-3766	168	7	the	the	DET
fnp-3766	168	8	induced	induced	ADJ
fnp-3766	168	9	aβ	aβ	NOUN
fnp-3766	168	10	pathology	pathology	NOUN
fnp-3766	168	11	exhibited	exhibit	VERB
fnp-3766	168	12	a	a	DET
fnp-3766	168	13	diffuse	diffuse	NOUN
fnp-3766	168	14	,	,	PUNCT
fnp-3766	168	15	thio	thio	NOUN
fnp-3766	168	16	-	-	PUNCT
fnp-3766	168	17	s	s	X
fnp-3766	168	18	negative	negative	ADJ
fnp-3766	168	19	morphology	morphology	NOUN
fnp-3766	168	20	(	(	PUNCT
fnp-3766	168	21	fig	fig	NOUN
fnp-3766	168	22	.	.	PUNCT
fnp-3766	168	23	s5	s5	PROPN
fnp-3766	168	24	)	)	PUNCT
fnp-3766	168	25	.	.	PUNCT
fnp-3766	169	1	the	the	DET
fnp-3766	169	2	levels	level	NOUN
fnp-3766	169	3	of	of	ADP
fnp-3766	169	4	induced	induce	VERB
fnp-3766	169	5	aβ	aβ	PRON
fnp-3766	169	6	pathology	pathology	NOUN
fnp-3766	169	7	in	in	ADP
fnp-3766	169	8	mice	mouse	NOUN
fnp-3766	169	9	that	that	SCONJ
fnp-3766	169	10	co	co	VERB
fnp-3766	169	11	-	-	ADJ
fnp-3766	169	12	expressed	express	VERB
fnp-3766	169	13	appsi	appsi	PROPN
fnp-3766	169	14	and	and	CCONJ
fnp-3766	169	15	tau	tau	PROPN
fnp-3766	169	16	-	-	PUNCT
fnp-3766	169	17	p301l	p301l	NOUN
fnp-3766	169	18	were	be	AUX
fnp-3766	169	19	similar	similar	ADJ
fnp-3766	169	20	to	to	ADP
fnp-3766	169	21	that	that	PRON
fnp-3766	169	22	of	of	ADP
fnp-3766	169	23	mice	mouse	NOUN
fnp-3766	169	24	that	that	PRON
fnp-3766	169	25	expressed	express	VERB
fnp-3766	169	26	only	only	ADV
fnp-3766	169	27	appsi	appsi	PROPN
fnp-3766	169	28	(	(	PUNCT
fnp-3766	169	29	fig	fig	NOUN
fnp-3766	169	30	.	.	PUNCT
fnp-3766	170	1	1b	1b	NUM
fnp-3766	170	2	versus	versus	ADP
fnp-3766	170	3	c	c	NOUN
fnp-3766	170	4	,	,	PUNCT
fnp-3766	170	5	s4a	s4a	NOUN
fnp-3766	170	6	versus	versus	ADP
fnp-3766	170	7	b	b	NOUN
fnp-3766	170	8	)	)	PUNCT
fnp-3766	170	9	.	.	PUNCT
fnp-3766	171	1	mice	mouse	NOUN
fnp-3766	171	2	that	that	PRON
fnp-3766	171	3	were	be	AUX
fnp-3766	171	4	transgenic	transgenic	NOUN
fnp-3766	171	5	for	for	ADP
fnp-3766	171	6	only	only	ADV
fnp-3766	171	7	tau	tau	PROPN
fnp-3766	171	8	-	-	PUNCT
fnp-3766	171	9	p301l	p301l	PROPN
fnp-3766	171	10	,	,	PUNCT
fnp-3766	171	11	or	or	CCONJ
fnp-3766	171	12	were	be	AUX
fnp-3766	171	13	non	non	ADJ
fnp-3766	171	14	-	-	ADJ
fnp-3766	171	15	transgenic	transgenic	ADJ
fnp-3766	171	16	,	,	PUNCT
fnp-3766	171	17	showed	show	VERB
fnp-3766	171	18	no	no	DET
fnp-3766	171	19	evidence	evidence	NOUN
fnp-3766	171	20	of	of	ADP
fnp-3766	171	21	aβ	aβ	NOUN
fnp-3766	171	22	deposition	deposition	NOUN
fnp-3766	171	23	(	(	PUNCT
fnp-3766	171	24	data	datum	NOUN
fnp-3766	171	25	not	not	PART
fnp-3766	171	26	shown	show	VERB
fnp-3766	171	27	)	)	PUNCT
fnp-3766	171	28	.	.	PUNCT
fnp-3766	172	1	to	to	PART
fnp-3766	172	2	compare	compare	VERB
fnp-3766	172	3	the	the	DET
fnp-3766	172	4	data	datum	NOUN
fnp-3766	172	5	across	across	ADP
fnp-3766	172	6	all	all	PRON
fnp-3766	172	7	of	of	ADP
fnp-3766	172	8	the	the	DET
fnp-3766	172	9	mice	mouse	NOUN
fnp-3766	172	10	examined	examine	VERB
fnp-3766	172	11	,	,	PUNCT
fnp-3766	172	12	aβ	aβ	DET
fnp-3766	172	13	pathology	pathology	NOUN
fnp-3766	172	14	was	be	AUX
fnp-3766	172	15	qualitatively	qualitatively	ADV
fnp-3766	172	16	scored	score	VERB
fnp-3766	172	17	by	by	ADP
fnp-3766	172	18	three	three	NUM
fnp-3766	172	19	independent	independent	ADJ
fnp-3766	172	20	observers	observer	NOUN
fnp-3766	172	21	(	(	PUNCT
fnp-3766	172	22	fig	fig	NOUN
fnp-3766	172	23	.	.	PUNCT
fnp-3766	173	1	1d	1d	NUM
fnp-3766	173	2	,	,	PUNCT
fnp-3766	173	3	e	e	NOUN
fnp-3766	173	4	)	)	PUNCT
fnp-3766	173	5	.	.	PUNCT
fnp-3766	174	1	at	at	ADP
fnp-3766	174	2	12	12	NUM
fnp-3766	174	3	months	month	NOUN
fnp-3766	174	4	,	,	PUNCT
fnp-3766	174	5	only	only	ADV
fnp-3766	174	6	pa	pa	PROPN
fnp-3766	174	7	4	4	NUM
fnp-3766	174	8	was	be	AUX
fnp-3766	174	9	scored	score	VERB
fnp-3766	174	10	as	as	ADP
fnp-3766	174	11	having	have	VERB
fnp-3766	174	12	a	a	DET
fnp-3766	174	13	level	level	NOUN
fnp-3766	174	14	of	of	ADP
fnp-3766	174	15	aβ	aβ	DET
fnp-3766	174	16	pathology	pathology	NOUN
fnp-3766	174	17	that	that	PRON
fnp-3766	174	18	approached	approach	VERB
fnp-3766	174	19	mice	mouse	NOUN
fnp-3766	174	20	injected	inject	VERB
fnp-3766	174	21	with	with	ADP
fnp-3766	174	22	the	the	DET
fnp-3766	174	23	ad	ad	NOUN
fnp-3766	174	24	cases	case	NOUN
fnp-3766	174	25	;	;	PUNCT
fnp-3766	174	26	both	both	PRON
fnp-3766	174	27	of	of	ADP
fnp-3766	174	28	which	which	PRON
fnp-3766	174	29	exhibited	exhibit	VERB
fnp-3766	174	30	widespread	widespread	ADJ
fnp-3766	174	31	,	,	PUNCT
fnp-3766	174	32	diffuse	diffuse	ADJ
fnp-3766	174	33	pathology	pathology	NOUN
fnp-3766	174	34	(	(	PUNCT
fnp-3766	174	35	fig	fig	NOUN
fnp-3766	174	36	.	.	PUNCT
fnp-3766	175	1	1b	1b	NUM
fnp-3766	175	2	,	,	PUNCT
fnp-3766	175	3	c	c	NOUN
fnp-3766	175	4	)	)	PUNCT
fnp-3766	175	5	.	.	PUNCT
fnp-3766	176	1	aβ	aβ	DET
fnp-3766	176	2	pathology	pathology	NOUN
fnp-3766	176	3	in	in	ADP
fnp-3766	176	4	mice	mouse	NOUN
fnp-3766	176	5	seeded	seed	VERB
fnp-3766	176	6	by	by	ADP
fnp-3766	176	7	pa	pa	PROPN
fnp-3766	176	8	1	1	NUM
fnp-3766	176	9	,	,	PUNCT
fnp-3766	176	10	2	2	NUM
fnp-3766	176	11	,	,	PUNCT
fnp-3766	176	12	and	and	CCONJ
fnp-3766	176	13	3	3	NUM
fnp-3766	176	14	was	be	AUX
fnp-3766	176	15	scored	score	VERB
fnp-3766	176	16	as	as	ADP
fnp-3766	176	17	less	less	ADV
fnp-3766	176	18	abundant	abundant	ADJ
fnp-3766	176	19	than	than	ADP
fnp-3766	176	20	in	in	ADP
fnp-3766	176	21	mice	mouse	NOUN
fnp-3766	176	22	seeded	seed	VERB
fnp-3766	176	23	by	by	ADP
fnp-3766	176	24	the	the	DET
fnp-3766	176	25	ad	ad	NOUN
fnp-3766	176	26	cases	case	NOUN
fnp-3766	176	27	(	(	PUNCT
fnp-3766	176	28	fig	fig	NOUN
fnp-3766	176	29	.	.	PUNCT
fnp-3766	177	1	1d	1d	NUM
fnp-3766	177	2	,	,	PUNCT
fnp-3766	177	3	e	e	NOUN
fnp-3766	177	4	)	)	PUNCT
fnp-3766	177	5	.	.	PUNCT
fnp-3766	178	1	we	we	PRON
fnp-3766	178	2	confirmed	confirm	VERB
fnp-3766	178	3	the	the	DET
fnp-3766	178	4	high	high	ADJ
fnp-3766	178	5	seeding	seeding	NOUN
fnp-3766	178	6	activity	activity	NOUN
fnp-3766	178	7	of	of	ADP
fnp-3766	178	8	ad	ad	NOUN
fnp-3766	178	9	1	1	NUM
fnp-3766	178	10	and	and	CCONJ
fnp-3766	178	11	2	2	NUM
fnp-3766	178	12	,	,	PUNCT
fnp-3766	178	13	and	and	CCONJ
fnp-3766	178	14	pa	pa	PROPN
fnp-3766	178	15	4	4	NUM
fnp-3766	178	16	by	by	ADP
fnp-3766	178	17	assessing	assess	VERB
fnp-3766	178	18	aβ	aβ	DET
fnp-3766	178	19	pathology	pathology	NOUN
fnp-3766	178	20	at	at	ADP
fnp-3766	178	21	9	9	NUM
fnp-3766	178	22	months	month	NOUN
fnp-3766	178	23	post	post	NOUN
fnp-3766	178	24	-	-	NOUN
fnp-3766	178	25	injection	injection	NOUN
fnp-3766	178	26	.	.	PUNCT
fnp-3766	179	1	although	although	SCONJ
fnp-3766	179	2	the	the	DET
fnp-3766	179	3	severity	severity	NOUN
fnp-3766	179	4	of	of	ADP
fnp-3766	179	5	pathology	pathology	NOUN
fnp-3766	179	6	varied	varied	ADJ
fnp-3766	179	7	,	,	PUNCT
fnp-3766	179	8	multiple	multiple	ADJ
fnp-3766	179	9	animals	animal	NOUN
fnp-3766	179	10	injected	inject	VERB
fnp-3766	179	11	with	with	ADP
fnp-3766	179	12	each	each	PRON
fnp-3766	179	13	of	of	ADP
fnp-3766	179	14	these	these	DET
fnp-3766	179	15	lysates	lysate	NOUN
fnp-3766	179	16	exhibited	exhibit	VERB
fnp-3766	179	17	aβ	aβ	ADP
fnp-3766	179	18	deposition	deposition	NOUN
fnp-3766	179	19	(	(	PUNCT
fnp-3766	179	20	fig	fig	NOUN
fnp-3766	179	21	.	.	PUNCT
fnp-3766	179	22	s6a	s6a	PROPN
fnp-3766	179	23	)	)	PUNCT
fnp-3766	179	24	.	.	PUNCT
fnp-3766	180	1	notably	notably	ADV
fnp-3766	180	2	,	,	PUNCT
fnp-3766	180	3	dilution	dilution	NOUN
fnp-3766	180	4	of	of	ADP
fnp-3766	180	5	the	the	DET
fnp-3766	180	6	brain	brain	NOUN
fnp-3766	180	7	lysates	lysate	NOUN
fnp-3766	180	8	by	by	ADP
fnp-3766	180	9	10	10	NUM
fnp-3766	180	10	-	-	NOUN
fnp-3766	180	11	fold	fold	VERB
fnp-3766	180	12	prior	prior	ADV
fnp-3766	180	13	to	to	ADP
fnp-3766	180	14	injection	injection	NOUN
fnp-3766	180	15	greatly	greatly	ADV
fnp-3766	180	16	diminished	diminish	VERB
fnp-3766	180	17	seeding	seeding	NOUN
fnp-3766	180	18	activity	activity	NOUN
fnp-3766	180	19	(	(	PUNCT
fnp-3766	180	20	fig	fig	NOUN
fnp-3766	180	21	.	.	PUNCT
fnp-3766	181	1	s6b	s6b	NOUN
fnp-3766	181	2	)	)	PUNCT
fnp-3766	181	3	.	.	PUNCT
fnp-3766	182	1	to	to	PART
fnp-3766	182	2	further	far	ADV
fnp-3766	182	3	examine	examine	VERB
fnp-3766	182	4	the	the	DET
fnp-3766	182	5	relative	relative	ADJ
fnp-3766	182	6	seeding	seed	VERB
fnp-3766	182	7	activity	activity	NOUN
fnp-3766	182	8	of	of	ADP
fnp-3766	182	9	pa	pa	PROPN
fnp-3766	182	10	lysates	lysate	NOUN
fnp-3766	182	11	,	,	PUNCT
fnp-3766	182	12	we	we	PRON
fnp-3766	182	13	injected	inject	VERB
fnp-3766	182	14	newborn	newborn	ADJ
fnp-3766	182	15	prp.appsi	prp.appsi	NOUN
fnp-3766	182	16	mice	mouse	NOUN
fnp-3766	182	17	with	with	ADP
fnp-3766	182	18	each	each	PRON
fnp-3766	182	19	of	of	ADP
fnp-3766	182	20	the	the	DET
fnp-3766	182	21	4	4	NUM
fnp-3766	182	22	pa	pa	PROPN
fnp-3766	182	23	lysates	lysate	NOUN
fnp-3766	182	24	and	and	CCONJ
fnp-3766	182	25	ndc	ndc	PROPN
fnp-3766	182	26	1	1	NUM
fnp-3766	182	27	,	,	PUNCT
fnp-3766	182	28	and	and	CCONJ
fnp-3766	182	29	analyzed	analyze	VERB
fnp-3766	182	30	pathology	pathology	NOUN
fnp-3766	182	31	at	at	ADP
fnp-3766	182	32	18	18	NUM
fnp-3766	182	33	months	month	NOUN
fnp-3766	182	34	post	post	NOUN
fnp-3766	182	35	-	-	NOUN
fnp-3766	182	36	injection	injection	NOUN
fnp-3766	182	37	.	.	PUNCT
fnp-3766	183	1	although	although	SCONJ
fnp-3766	183	2	the	the	DET
fnp-3766	183	3	mice	mouse	NOUN
fnp-3766	183	4	injected	inject	VERB
fnp-3766	183	5	with	with	ADP
fnp-3766	183	6	the	the	DET
fnp-3766	183	7	pa	pa	PROPN
fnp-3766	183	8	lysates	lysate	NOUN
fnp-3766	183	9	appeared	appear	VERB
fnp-3766	183	10	to	to	PART
fnp-3766	183	11	have	have	VERB
fnp-3766	183	12	more	more	ADV
fnp-3766	183	13	severe	severe	ADJ
fnp-3766	183	14	aβ	aβ	ADP
fnp-3766	183	15	deposition	deposition	NOUN
fnp-3766	183	16	,	,	PUNCT
fnp-3766	183	17	we	we	PRON
fnp-3766	183	18	also	also	ADV
fnp-3766	183	19	observed	observe	VERB
fnp-3766	183	20	some	some	DET
fnp-3766	183	21	significant	significant	ADJ
fnp-3766	183	22	aβ	aβ	PRON
fnp-3766	183	23	pathology	pathology	NOUN
fnp-3766	183	24	in	in	ADP
fnp-3766	183	25	animals	animal	NOUN
fnp-3766	183	26	injected	inject	VERB
fnp-3766	183	27	with	with	ADP
fnp-3766	183	28	the	the	DET
fnp-3766	183	29	ndc	ndc	NOUN
fnp-3766	183	30	lysate	lysate	NOUN
fnp-3766	183	31	(	(	PUNCT
fnp-3766	183	32	fig	fig	NOUN
fnp-3766	183	33	.	.	PUNCT
fnp-3766	184	1	s7	s7	NOUN
fnp-3766	184	2	)	)	PUNCT
fnp-3766	184	3	.	.	PUNCT
fnp-3766	185	1	whether	whether	SCONJ
fnp-3766	185	2	this	this	DET
fnp-3766	185	3	outcome	outcome	NOUN
fnp-3766	185	4	was	be	AUX
fnp-3766	185	5	due	due	ADJ
fnp-3766	185	6	to	to	ADP
fnp-3766	185	7	some	some	DET
fnp-3766	185	8	small	small	ADJ
fnp-3766	185	9	amount	amount	NOUN
fnp-3766	185	10	of	of	ADP
fnp-3766	185	11	aβ	aβ	NOUN
fnp-3766	185	12	seed	seed	NOUN
fnp-3766	185	13	in	in	ADP
fnp-3766	185	14	the	the	DET
fnp-3766	185	15	ndc	ndc	NOUN
fnp-3766	185	16	1	1	NUM
fnp-3766	185	17	will	will	AUX
fnp-3766	185	18	require	require	VERB
fnp-3766	185	19	further	further	ADJ
fnp-3766	185	20	study	study	NOUN
fnp-3766	185	21	.	.	PUNCT
fnp-3766	186	1	collectively	collectively	ADV
fnp-3766	186	2	,	,	PUNCT
fnp-3766	186	3	these	these	DET
fnp-3766	186	4	studies	study	NOUN
fnp-3766	186	5	demonstrated	demonstrate	VERB
fnp-3766	186	6	that	that	SCONJ
fnp-3766	186	7	ad	ad	NOUN
fnp-3766	186	8	and	and	CCONJ
fnp-3766	186	9	pa	pa	PROPN
fnp-3766	186	10	brains	brain	NOUN
fnp-3766	186	11	contain	contain	VERB
fnp-3766	186	12	misfolded	misfolded	ADJ
fnp-3766	186	13	forms	form	NOUN
fnp-3766	186	14	of	of	ADP
fnp-3766	186	15	aβ	aβ	PRON
fnp-3766	186	16	that	that	DET
fnp-3766	186	17	preferentially	preferentially	ADV
fnp-3766	186	18	seed	seed	NOUN
fnp-3766	186	19	diffuse	diffuse	NOUN
fnp-3766	186	20	aβ	aβ	ADP
fnp-3766	186	21	pathology	pathology	NOUN
fnp-3766	186	22	.	.	PUNCT
fnp-3766	187	1	fig	fig	NOUN
fnp-3766	187	2	.	.	PUNCT
fnp-3766	188	1	1	1	NUM
fnp-3766	188	2	cerebral	cerebral	ADJ
fnp-3766	188	3	injection	injection	NOUN
fnp-3766	188	4	of	of	ADP
fnp-3766	188	5	brain	brain	NOUN
fnp-3766	188	6	lysate	lysate	NOUN
fnp-3766	188	7	at	at	ADP
fnp-3766	188	8	p0	p0	NOUN
fnp-3766	188	9	induces	induce	VERB
fnp-3766	188	10	widespread	widespread	ADJ
fnp-3766	188	11	,	,	PUNCT
fnp-3766	188	12	robust	robust	ADJ
fnp-3766	188	13	amyloid	amyloid	NOUN
fnp-3766	188	14	deposition	deposition	NOUN
fnp-3766	188	15	.	.	PUNCT
fnp-3766	189	1	overall	overall	ADJ
fnp-3766	189	2	schematic	schematic	ADJ
fnp-3766	189	3	of	of	ADP
fnp-3766	189	4	experiments	experiment	NOUN
fnp-3766	189	5	(	(	PUNCT
fnp-3766	189	6	a	a	DET
fnp-3766	189	7	)	)	PUNCT
fnp-3766	189	8	images	image	NOUN
fnp-3766	189	9	of	of	ADP
fnp-3766	189	10	prp.appsi/tau-p301l	prp.appsi/tau-p301l	NOUN
fnp-3766	189	11	(	(	PUNCT
fnp-3766	189	12	b	b	NOUN
fnp-3766	189	13	)	)	PUNCT
fnp-3766	189	14	and	and	CCONJ
fnp-3766	189	15	prp.appsi	prp.appsi	NUM
fnp-3766	189	16	(	(	PUNCT
fnp-3766	189	17	c	c	X
fnp-3766	189	18	)	)	PUNCT
fnp-3766	189	19	mice	mouse	NOUN
fnp-3766	189	20	injected	inject	VERB
fnp-3766	189	21	with	with	ADP
fnp-3766	189	22	ad	ad	NOUN
fnp-3766	189	23	,	,	PUNCT
fnp-3766	189	24	pa	pa	PROPN
fnp-3766	189	25	,	,	PUNCT
fnp-3766	189	26	or	or	CCONJ
fnp-3766	189	27	ndc	ndc	NOUN
fnp-3766	189	28	lysate	lysate	NOUN
fnp-3766	189	29	at	at	ADP
fnp-3766	189	30	p0	p0	NOUN
fnp-3766	189	31	.	.	PUNCT
fnp-3766	190	1	brain	brain	NOUN
fnp-3766	190	2	sections	section	NOUN
fnp-3766	190	3	(	(	PUNCT
fnp-3766	190	4	hemibrain	hemibrain	ADV
fnp-3766	190	5	)	)	PUNCT
fnp-3766	190	6	stained	stain	VERB
fnp-3766	190	7	with	with	ADP
fnp-3766	190	8	biotinylated	biotinylate	VERB
fnp-3766	190	9	anti	anti	ADJ
fnp-3766	190	10	-	-	ADJ
fnp-3766	190	11	aβ	aβ	ADJ
fnp-3766	190	12	mab	mab	NOUN
fnp-3766	190	13	ab5	ab5	NOUN
fnp-3766	190	14	(	(	PUNCT
fnp-3766	190	15	anti	anti	ADJ
fnp-3766	190	16	-	-	ADJ
fnp-3766	190	17	aβ	aβ	ADJ
fnp-3766	190	18	1	1	NUM
fnp-3766	190	19	-	-	SYM
fnp-3766	190	20	16	16	NUM
fnp-3766	190	21	)	)	PUNCT
fnp-3766	190	22	and	and	CCONJ
fnp-3766	190	23	counterstained	counterstaine	VERB
fnp-3766	190	24	with	with	ADP
fnp-3766	190	25	hematoxylin	hematoxylin	PROPN
fnp-3766	190	26	.	.	PUNCT
fnp-3766	191	1	cases	case	NOUN
fnp-3766	191	2	with	with	ADP
fnp-3766	191	3	the	the	DET
fnp-3766	191	4	most	most	ADV
fnp-3766	191	5	abundant	abundant	ADJ
fnp-3766	191	6	amyloid	amyloid	NOUN
fnp-3766	191	7	pathology	pathology	NOUN
fnp-3766	191	8	are	be	AUX
fnp-3766	191	9	shown	show	VERB
fnp-3766	191	10	.	.	PUNCT
fnp-3766	192	1	scale	scale	NOUN
fnp-3766	192	2	bar	bar	NOUN
fnp-3766	192	3	:	:	PUNCT
fnp-3766	192	4	100	100	NUM
fnp-3766	192	5	μm	μm	NOUN
fnp-3766	192	6	.	.	PUNCT
fnp-3766	193	1	qualitative	qualitative	ADJ
fnp-3766	193	2	analysis	analysis	NOUN
fnp-3766	193	3	of	of	ADP
fnp-3766	193	4	amyloid	amyloid	NOUN
fnp-3766	193	5	deposition	deposition	NOUN
fnp-3766	193	6	in	in	ADP
fnp-3766	193	7	seeded	seeded	ADJ
fnp-3766	193	8	prp.appsi/tau-p301l	prp.appsi/tau-p301l	NOUN
fnp-3766	193	9	(	(	PUNCT
fnp-3766	193	10	d	d	NOUN
fnp-3766	193	11	)	)	PUNCT
fnp-3766	193	12	and	and	CCONJ
fnp-3766	193	13	prp.appsi	prp.appsi	PROPN
fnp-3766	193	14	(	(	PUNCT
fnp-3766	193	15	e	e	NOUN
fnp-3766	193	16	)	)	PUNCT
fnp-3766	193	17	mice	mouse	NOUN
fnp-3766	193	18	.	.	PUNCT
fnp-3766	194	1	three	three	NUM
fnp-3766	194	2	observers	observer	NOUN
fnp-3766	194	3	independently	independently	ADV
fnp-3766	194	4	scored	score	VERB
fnp-3766	194	5	representative	representative	ADJ
fnp-3766	194	6	slides	slide	NOUN
fnp-3766	194	7	from	from	ADP
fnp-3766	194	8	each	each	DET
fnp-3766	194	9	seeded	seeded	ADJ
fnp-3766	194	10	mouse	mouse	NOUN
fnp-3766	194	11	.	.	PUNCT
fnp-3766	195	1	the	the	DET
fnp-3766	195	2	amyloid	amyloid	NOUN
fnp-3766	195	3	pathology	pathology	NOUN
fnp-3766	195	4	in	in	ADP
fnp-3766	195	5	each	each	DET
fnp-3766	195	6	mouse	mouse	NOUN
fnp-3766	195	7	was	be	AUX
fnp-3766	195	8	categorized	categorize	VERB
fnp-3766	195	9	on	on	ADP
fnp-3766	195	10	a	a	DET
fnp-3766	195	11	scale	scale	NOUN
fnp-3766	195	12	from	from	ADP
fnp-3766	195	13	(	(	PUNCT
fnp-3766	195	14	-	-	INTJ
fnp-3766	195	15	)	)	PUNCT
fnp-3766	195	16	as	as	ADP
fnp-3766	195	17	no	no	DET
fnp-3766	195	18	pathology	pathology	NOUN
fnp-3766	195	19	to	to	ADP
fnp-3766	195	20	(	(	PUNCT
fnp-3766	195	21	+	+	PROPN
fnp-3766	195	22	+	+	NOUN
fnp-3766	195	23	+	+	NOUN
fnp-3766	195	24	)	)	PUNCT
fnp-3766	195	25	as	as	ADP
fnp-3766	195	26	abundant	abundant	ADJ
fnp-3766	195	27	pathology	pathology	NOUN
fnp-3766	195	28	.	.	PUNCT
fnp-3766	196	1	each	each	DET
fnp-3766	196	2	point	point	NOUN
fnp-3766	196	3	represents	represent	VERB
fnp-3766	196	4	a	a	DET
fnp-3766	196	5	rating	rating	NOUN
fnp-3766	196	6	score	score	NOUN
fnp-3766	196	7	by	by	ADP
fnp-3766	196	8	an	an	DET
fnp-3766	196	9	observer	observer	NOUN
fnp-3766	196	10	(	(	PUNCT
fnp-3766	196	11	3	3	NUM
fnp-3766	196	12	observations	observation	NOUN
fnp-3766	196	13	per	per	ADP
fnp-3766	196	14	animal	animal	NOUN
fnp-3766	196	15	)	)	PUNCT
fnp-3766	196	16	.	.	PUNCT
fnp-3766	197	1	the	the	DET
fnp-3766	197	2	number	number	NOUN
fnp-3766	197	3	of	of	ADP
fnp-3766	197	4	seeded	seeded	ADJ
fnp-3766	197	5	mice	mouse	NOUN
fnp-3766	197	6	for	for	ADP
fnp-3766	197	7	each	each	DET
fnp-3766	197	8	scale	scale	NOUN
fnp-3766	197	9	of	of	ADP
fnp-3766	197	10	amyloid	amyloid	NOUN
fnp-3766	197	11	burden	burden	NOUN
fnp-3766	197	12	by	by	ADP
fnp-3766	197	13	the	the	DET
fnp-3766	197	14	three	three	NUM
fnp-3766	197	15	observers	observer	NOUN
fnp-3766	197	16	is	be	AUX
fnp-3766	197	17	reported	report	VERB
fnp-3766	197	18	.	.	PUNCT
fnp-3766	198	1	a	a	DET
fnp-3766	198	2	subset	subset	NOUN
fnp-3766	198	3	of	of	ADP
fnp-3766	198	4	mice	mouse	NOUN
fnp-3766	198	5	injected	inject	VERB
fnp-3766	198	6	with	with	ADP
fnp-3766	198	7	ndc	ndc	NOUN
fnp-3766	198	8	lysate	lysate	NOUN
fnp-3766	198	9	were	be	AUX
fnp-3766	198	10	rated	rate	VERB
fnp-3766	198	11	as	as	ADP
fnp-3766	198	12	+	+	CCONJ
fnp-3766	198	13	based	base	VERB
fnp-3766	198	14	on	on	ADP
fnp-3766	198	15	3	3	NUM
fnp-3766	198	16	-	-	SYM
fnp-3766	198	17	5	5	NUM
fnp-3766	198	18	plaques	plaque	NOUN
fnp-3766	198	19	per	per	ADP
fnp-3766	198	20	section	section	NOUN
fnp-3766	198	21	,	,	PUNCT
fnp-3766	198	22	and	and	CCONJ
fnp-3766	198	23	thus	thus	ADV
fnp-3766	198	24	we	we	PRON
fnp-3766	198	25	set	set	VERB
fnp-3766	198	26	this	this	DET
fnp-3766	198	27	rating	rating	NOUN
fnp-3766	198	28	as	as	ADP
fnp-3766	198	29	baseline	baseline	NOUN
fnp-3766	198	30	(	(	PUNCT
fnp-3766	198	31	marked	mark	VERB
fnp-3766	198	32	by	by	ADP
fnp-3766	198	33	a	a	DET
fnp-3766	198	34	dash	dash	NOUN
fnp-3766	198	35	line	line	NOUN
fnp-3766	198	36	)	)	PUNCT
fnp-3766	198	37	.	.	PUNCT
fnp-3766	199	1	only	only	ADV
fnp-3766	199	2	the	the	DET
fnp-3766	199	3	two	two	NUM
fnp-3766	199	4	ad	ad	NOUN
fnp-3766	199	5	cases	case	NOUN
fnp-3766	199	6	and	and	CCONJ
fnp-3766	199	7	pa	pa	PROPN
fnp-3766	199	8	4	4	NUM
fnp-3766	199	9	consistently	consistently	ADV
fnp-3766	199	10	scored	score	VERB
fnp-3766	199	11	above	above	ADP
fnp-3766	199	12	+	+	PROPN
fnp-3766	199	13	.	.	PUNCT
fnp-3766	200	1	the	the	DET
fnp-3766	200	2	number	number	NOUN
fnp-3766	200	3	of	of	ADP
fnp-3766	200	4	prp.appsi/tau-p301l	prp.appsi/tau-p301l	NOUN
fnp-3766	200	5	or	or	CCONJ
fnp-3766	200	6	prp.appsi	prp.appsi	NUM
fnp-3766	200	7	mice	mouse	NOUN
fnp-3766	200	8	injected	inject	VERB
fnp-3766	200	9	with	with	ADP
fnp-3766	200	10	each	each	DET
fnp-3766	200	11	lysate	lysate	NOUN
fnp-3766	200	12	,	,	PUNCT
fnp-3766	200	13	respectively	respectively	ADV
fnp-3766	200	14	,	,	PUNCT
fnp-3766	200	15	were	be	AUX
fnp-3766	200	16	as	as	SCONJ
fnp-3766	200	17	follows	follow	VERB
fnp-3766	200	18	:	:	PUNCT
fnp-3766	200	19	ad	ad	NOUN
fnp-3766	200	20	1	1	NUM
fnp-3766	200	21	:	:	PUNCT
fnp-3766	200	22	n=4	n=4	NOUN
fnp-3766	200	23	,	,	PUNCT
fnp-3766	200	24	n=3	n=3	PRON
fnp-3766	200	25	;	;	PUNCT
fnp-3766	200	26	ad	ad	NOUN
fnp-3766	200	27	2	2	NUM
fnp-3766	200	28	:	:	PUNCT
fnp-3766	200	29	n=4	n=4	NOUN
fnp-3766	200	30	,	,	PUNCT
fnp-3766	200	31	n=3	n=3	PRON
fnp-3766	200	32	;	;	PUNCT
fnp-3766	200	33	pa	pa	PROPN
fnp-3766	200	34	1	1	NUM
fnp-3766	200	35	:	:	PUNCT
fnp-3766	200	36	n=3	n=3	NOUN
fnp-3766	200	37	,	,	PUNCT
fnp-3766	200	38	n=3	n=3	PRON
fnp-3766	200	39	;	;	PUNCT
fnp-3766	200	40	pa	pa	PROPN
fnp-3766	200	41	2	2	NUM
fnp-3766	200	42	:	:	PUNCT
fnp-3766	200	43	n=3	n=3	NOUN
fnp-3766	200	44	,	,	PUNCT
fnp-3766	200	45	n=5	n=5	NUM
fnp-3766	200	46	;	;	PUNCT
fnp-3766	200	47	pa	pa	PROPN
fnp-3766	200	48	3	3	NUM
fnp-3766	200	49	:	:	PUNCT
fnp-3766	200	50	n=5	n=5	NUM
fnp-3766	200	51	,	,	PUNCT
fnp-3766	200	52	n=4	n=4	NUM
fnp-3766	200	53	;	;	PUNCT
fnp-3766	200	54	pa	pa	PROPN
fnp-3766	200	55	4	4	NUM
fnp-3766	200	56	:	:	PUNCT
fnp-3766	200	57	n=2	n=2	ADV
fnp-3766	200	58	,	,	PUNCT
fnp-3766	200	59	n=5	n=5	PROPN
fnp-3766	200	60	;	;	PUNCT
fnp-3766	200	61	ndc	ndc	PROPN
fnp-3766	200	62	1	1	NUM
fnp-3766	200	63	:	:	PUNCT
fnp-3766	200	64	n=3	n=3	NOUN
fnp-3766	200	65	,	,	PUNCT
fnp-3766	200	66	n=3	n=3	PRON
fnp-3766	200	67	;	;	PUNCT
fnp-3766	200	68	ndc	ndc	NOUN
fnp-3766	200	69	2	2	NUM
fnp-3766	200	70	:	:	PUNCT
fnp-3766	200	71	n=5	n=5	NUM
fnp-3766	200	72	,	,	PUNCT
fnp-3766	200	73	n=5	n=5	PRON
fnp-3766	200	74	;	;	PUNCT
fnp-3766	200	75	uninjected	uninjected	ADJ
fnp-3766	200	76	:	:	PUNCT
fnp-3766	200	77	n=3	n=3	NOUN
fnp-3766	200	78	,	,	PUNCT
fnp-3766	200	79	n=3	n=3	PRON
fnp-3766	200	80	.	.	NOUN
fnp-3766	201	1	two	two	NUM
fnp-3766	201	2	of	of	ADP
fnp-3766	201	3	the	the	DET
fnp-3766	201	4	donor	donor	NOUN
fnp-3766	201	5	cases	case	NOUN
fnp-3766	201	6	were	be	AUX
fnp-3766	201	7	identified	identify	VERB
fnp-3766	201	8	as	as	ADP
fnp-3766	201	9	having	have	VERB
fnp-3766	201	10	caa	caa	NOUN
fnp-3766	201	11	pathology	pathology	NOUN
fnp-3766	201	12	,	,	PUNCT
fnp-3766	201	13	ad	ad	NOUN
fnp-3766	201	14	1	1	NUM
fnp-3766	201	15	and	and	CCONJ
fnp-3766	201	16	pa	pa	PROPN
fnp-3766	201	17	3	3	NUM
fnp-3766	201	18	,	,	PUNCT
fnp-3766	201	19	and	and	CCONJ
fnp-3766	201	20	were	be	AUX
fnp-3766	201	21	scored	score	VERB
fnp-3766	201	22	1	1	NUM
fnp-3766	201	23	+	+	NUM
fnp-3766	201	24	and	and	CCONJ
fnp-3766	201	25	2	2	NUM
fnp-3766	201	26	+	+	NOUN
fnp-3766	201	27	-3	-3	ADJ
fnp-3766	201	28	+	+	ADJ
fnp-3766	201	29	,	,	PUNCT
fnp-3766	201	30	respectively	respectively	ADV
fnp-3766	201	31	(	(	PUNCT
fnp-3766	201	32	table	table	NOUN
fnp-3766	201	33	1	1	NUM
fnp-3766	201	34	)	)	PUNCT
fnp-3766	201	35	.	.	PUNCT
fnp-3766	202	1	to	to	PART
fnp-3766	202	2	determine	determine	VERB
fnp-3766	202	3	if	if	SCONJ
fnp-3766	202	4	caa	caa	PROPN
fnp-3766	202	5	pathology	pathology	NOUN
fnp-3766	202	6	was	be	AUX
fnp-3766	202	7	seeded	seed	VERB
fnp-3766	202	8	in	in	ADP
fnp-3766	202	9	the	the	DET
fnp-3766	202	10	recipient	recipient	NOUN
fnp-3766	202	11	mice	mice	NOUN
fnp-3766	202	12	,	,	PUNCT
fnp-3766	202	13	we	we	PRON
fnp-3766	202	14	stained	stain	VERB
fnp-3766	202	15	sections	section	NOUN
fnp-3766	202	16	with	with	ADP
fnp-3766	202	17	thio	thio	NOUN
fnp-3766	202	18	-	-	PUNCT
fnp-3766	202	19	s	s	NOUN
fnp-3766	202	20	and	and	CCONJ
fnp-3766	202	21	searched	search	VERB
fnp-3766	202	22	for	for	ADP
fnp-3766	202	23	evidence	evidence	NOUN
fnp-3766	202	24	of	of	ADP
fnp-3766	202	25	vascular	vascular	ADJ
fnp-3766	202	26	amyloid	amyloid	NOUN
fnp-3766	202	27	.	.	PUNCT
fnp-3766	203	1	in	in	ADP
fnp-3766	203	2	mice	mouse	NOUN
fnp-3766	203	3	seeded	seed	VERB
fnp-3766	203	4	with	with	ADP
fnp-3766	203	5	pa	pa	PROPN
fnp-3766	203	6	3	3	NUM
fnp-3766	203	7	,	,	PUNCT
fnp-3766	203	8	we	we	PRON
fnp-3766	203	9	observed	observe	VERB
fnp-3766	203	10	thio	thio	NOUN
fnp-3766	203	11	-	-	PUNCT
fnp-3766	203	12	s	s	NOUN
fnp-3766	203	13	positive	positive	ADJ
fnp-3766	203	14	,	,	PUNCT
fnp-3766	203	15	vascular	vascular	ADJ
fnp-3766	203	16	pathology	pathology	NOUN
fnp-3766	203	17	in	in	ADP
fnp-3766	203	18	6	6	NUM
fnp-3766	203	19	of	of	ADP
fnp-3766	203	20	the	the	DET
fnp-3766	203	21	7	7	NUM
fnp-3766	203	22	recipient	recipient	NOUN
fnp-3766	203	23	mice	mouse	NOUN
fnp-3766	203	24	;	;	PUNCT
fnp-3766	203	25	however	however	ADV
fnp-3766	203	26	,	,	PUNCT
fnp-3766	203	27	the	the	DET
fnp-3766	203	28	incidence	incidence	NOUN
fnp-3766	203	29	of	of	ADP
fnp-3766	203	30	this	this	DET
fnp-3766	203	31	pathology	pathology	NOUN
fnp-3766	203	32	was	be	AUX
fnp-3766	203	33	limited	limit	VERB
fnp-3766	203	34	(	(	PUNCT
fnp-3766	203	35	fig	fig	NOUN
fnp-3766	203	36	.	.	PUNCT
fnp-3766	204	1	s8	s8	PROPN
fnp-3766	204	2	)	)	PUNCT
fnp-3766	204	3	.	.	PUNCT
fnp-3766	205	1	although	although	SCONJ
fnp-3766	205	2	ad	ad	NOUN
fnp-3766	205	3	1	1	NUM
fnp-3766	205	4	also	also	ADV
fnp-3766	205	5	contained	contain	VERB
fnp-3766	205	6	caa	caa	PROPN
fnp-3766	205	7	pathology	pathology	NOUN
fnp-3766	205	8	,	,	PUNCT
fnp-3766	205	9	we	we	PRON
fnp-3766	205	10	did	do	AUX
fnp-3766	205	11	not	not	PART
fnp-3766	205	12	observe	observe	VERB
fnp-3766	205	13	thio	thio	NOUN
fnp-3766	205	14	-	-	PUNCT
fnp-3766	205	15	s	s	NOUN
fnp-3766	205	16	positive	positive	ADJ
fnp-3766	205	17	,	,	PUNCT
fnp-3766	205	18	vascular	vascular	ADJ
fnp-3766	205	19	pathology	pathology	NOUN
fnp-3766	205	20	in	in	ADP
fnp-3766	205	21	mice	mouse	NOUN
fnp-3766	205	22	seeded	seed	VERB
fnp-3766	205	23	by	by	ADP
fnp-3766	205	24	this	this	DET
fnp-3766	205	25	homogenate	homogenate	NOUN
fnp-3766	205	26	.	.	PUNCT
fnp-3766	206	1	these	these	DET
fnp-3766	206	2	findings	finding	NOUN
fnp-3766	206	3	suggest	suggest	VERB
fnp-3766	206	4	that	that	SCONJ
fnp-3766	206	5	it	it	PRON
fnp-3766	206	6	may	may	AUX
fnp-3766	206	7	be	be	AUX
fnp-3766	206	8	possible	possible	ADJ
fnp-3766	206	9	to	to	PART
fnp-3766	206	10	selectively	selectively	ADV
fnp-3766	206	11	increase	increase	VERB
fnp-3766	206	12	caa	caa	NOUN
fnp-3766	206	13	using	use	VERB
fnp-3766	206	14	seeding	seeding	NOUN
fnp-3766	206	15	,	,	PUNCT
fnp-3766	206	16	but	but	CCONJ
fnp-3766	206	17	enhancing	enhance	VERB
fnp-3766	206	18	such	such	ADJ
fnp-3766	206	19	pathology	pathology	NOUN
fnp-3766	206	20	may	may	AUX
fnp-3766	206	21	require	require	VERB
fnp-3766	206	22	purification	purification	NOUN
fnp-3766	206	23	of	of	ADP
fnp-3766	206	24	cerebral	cerebral	ADJ
fnp-3766	206	25	vessels	vessel	NOUN
fnp-3766	206	26	before	before	ADP
fnp-3766	206	27	preparation	preparation	NOUN
fnp-3766	206	28	of	of	ADP
fnp-3766	206	29	the	the	DET
fnp-3766	206	30	seeds	seed	NOUN
fnp-3766	206	31	.	.	PUNCT
fnp-3766	207	1	we	we	PRON
fnp-3766	207	2	biochemically	biochemically	ADV
fnp-3766	207	3	confirmed	confirm	VERB
fnp-3766	207	4	our	our	PRON
fnp-3766	207	5	histological	histological	ADJ
fnp-3766	207	6	data	datum	NOUN
fnp-3766	207	7	by	by	ADP
fnp-3766	207	8	analyzing	analyze	VERB
fnp-3766	207	9	aβ	aβ	ADP
fnp-3766	207	10	levels	level	NOUN
fnp-3766	207	11	from	from	ADP
fnp-3766	207	12	sequentially	sequentially	ADV
fnp-3766	207	13	extracted	extract	VERB
fnp-3766	207	14	brain	brain	NOUN
fnp-3766	207	15	lysates	lysate	NOUN
fnp-3766	207	16	using	use	VERB
fnp-3766	207	17	c	c	NOUN
fnp-3766	207	18	-	-	PUNCT
fnp-3766	207	19	terminal	terminal	ADJ
fnp-3766	207	20	specific	specific	ADJ
fnp-3766	207	21	antibodies	antibody	NOUN
fnp-3766	207	22	in	in	ADP
fnp-3766	207	23	sandwich	sandwich	NOUN
fnp-3766	207	24	elisas	elisa	NOUN
fnp-3766	207	25	to	to	PART
fnp-3766	207	26	measure	measure	VERB
fnp-3766	207	27	aβ40	aβ40	PROPN
fnp-3766	207	28	and	and	CCONJ
fnp-3766	207	29	aβ42	aβ42	PROPN
fnp-3766	207	30	specifically	specifically	ADV
fnp-3766	207	31	.	.	PUNCT
fnp-3766	208	1	in	in	ADP
fnp-3766	208	2	our	our	PRON
fnp-3766	208	3	aβ	aβ	NOUN
fnp-3766	208	4	elisas	elisa	NOUN
fnp-3766	208	5	the	the	DET
fnp-3766	208	6	detection	detection	NOUN
fnp-3766	208	7	limit	limit	NOUN
fnp-3766	208	8	was	be	AUX
fnp-3766	208	9	approximately	approximately	ADV
fnp-3766	208	10	0.04	0.04	NUM
fnp-3766	208	11	pmol	pmol	NOUN
fnp-3766	208	12	/	/	SYM
fnp-3766	208	13	g.	g.	PROPN
fnp-3766	208	14	in	in	ADP
fnp-3766	208	15	the	the	DET
fnp-3766	208	16	brains	brain	NOUN
fnp-3766	208	17	of	of	ADP
fnp-3766	208	18	all	all	DET
fnp-3766	208	19	seeded	seeded	ADJ
fnp-3766	208	20	mice	mouse	NOUN
fnp-3766	208	21	,	,	PUNCT
fnp-3766	208	22	the	the	DET
fnp-3766	208	23	levels	level	NOUN
fnp-3766	208	24	of	of	ADP
fnp-3766	208	25	aβ40	aβ40	PROPN
fnp-3766	208	26	,	,	PUNCT
fnp-3766	208	27	both	both	DET
fnp-3766	208	28	sds	sds	NOUN
fnp-3766	208	29	-	-	PUNCT
fnp-3766	208	30	soluble	soluble	ADJ
fnp-3766	208	31	and	and	CCONJ
fnp-3766	208	32	fa	fa	NOUN
fnp-3766	208	33	,	,	PUNCT
fnp-3766	208	34	were	be	AUX
fnp-3766	208	35	10	10	NUM
fnp-3766	208	36	-	-	SYM
fnp-3766	208	37	100	100	NUM
fnp-3766	208	38	-	-	NOUN
fnp-3766	208	39	fold	fold	VERB
fnp-3766	208	40	lower	low	ADJ
fnp-3766	208	41	than	than	ADP
fnp-3766	208	42	that	that	PRON
fnp-3766	208	43	of	of	ADP
fnp-3766	208	44	aβ42	aβ42	PROPN
fnp-3766	208	45	(	(	PUNCT
fnp-3766	208	46	fig	fig	NOUN
fnp-3766	208	47	.	.	PUNCT
fnp-3766	209	1	2a	2a	NUM
fnp-3766	209	2	,	,	PUNCT
fnp-3766	209	3	b	b	NOUN
fnp-3766	209	4	)	)	PUNCT
fnp-3766	209	5	.	.	PUNCT
fnp-3766	210	1	consistent	consistent	ADJ
fnp-3766	210	2	with	with	ADP
fnp-3766	210	3	the	the	DET
fnp-3766	210	4	presence	presence	NOUN
fnp-3766	210	5	of	of	ADP
fnp-3766	210	6	abundant	abundant	ADJ
fnp-3766	210	7	diffuse	diffuse	NOUN
fnp-3766	210	8	aβ	aβ	ADP
fnp-3766	210	9	pathology	pathology	NOUN
fnp-3766	210	10	,	,	PUNCT
fnp-3766	210	11	we	we	PRON
fnp-3766	210	12	detected	detect	VERB
fnp-3766	210	13	elevated	elevated	ADJ
fnp-3766	210	14	levels	level	NOUN
fnp-3766	210	15	of	of	ADP
fnp-3766	210	16	aβ42	aβ42	PROPN
fnp-3766	210	17	in	in	ADP
fnp-3766	210	18	sds	sds	NOUN
fnp-3766	210	19	-	-	PUNCT
fnp-3766	210	20	soluble	soluble	ADJ
fnp-3766	210	21	fractions	fraction	NOUN
fnp-3766	210	22	from	from	ADP
fnp-3766	210	23	mice	mouse	NOUN
fnp-3766	210	24	seeded	seed	VERB
fnp-3766	210	25	with	with	ADP
fnp-3766	210	26	ad	ad	NOUN
fnp-3766	210	27	1	1	NUM
fnp-3766	210	28	and	and	CCONJ
fnp-3766	210	29	2	2	NUM
fnp-3766	210	30	,	,	PUNCT
fnp-3766	210	31	and	and	CCONJ
fnp-3766	210	32	pa	pa	PROPN
fnp-3766	210	33	4	4	NUM
fnp-3766	210	34	(	(	PUNCT
fnp-3766	210	35	fig	fig	NOUN
fnp-3766	210	36	.	.	PUNCT
fnp-3766	211	1	2c	2c	NUM
fnp-3766	211	2	)	)	PUNCT
fnp-3766	211	3	.	.	PUNCT
fnp-3766	212	1	somewhat	somewhat	ADV
fnp-3766	212	2	surprisingly	surprisingly	ADV
fnp-3766	212	3	,	,	PUNCT
fnp-3766	212	4	the	the	DET
fnp-3766	212	5	levels	level	NOUN
fnp-3766	212	6	of	of	ADP
fnp-3766	212	7	aβ42	aβ42	PROPN
fnp-3766	212	8	in	in	ADP
fnp-3766	212	9	the	the	DET
fnp-3766	212	10	fa	fa	NOUN
fnp-3766	212	11	-	-	PUNCT
fnp-3766	212	12	soluble	soluble	ADJ
fnp-3766	212	13	fractions	fraction	NOUN
fnp-3766	212	14	were	be	AUX
fnp-3766	212	15	similar	similar	ADJ
fnp-3766	212	16	to	to	ADP
fnp-3766	212	17	that	that	PRON
fnp-3766	212	18	of	of	ADP
fnp-3766	212	19	the	the	DET
fnp-3766	212	20	sds	sds	PROPN
fnp-3766	212	21	fraction	fraction	NOUN
fnp-3766	212	22	despite	despite	SCONJ
fnp-3766	212	23	the	the	DET
fnp-3766	212	24	absence	absence	NOUN
fnp-3766	212	25	of	of	ADP
fnp-3766	212	26	cored	core	VERB
fnp-3766	212	27	aβ	aβ	NUM
fnp-3766	212	28	deposits	deposit	NOUN
fnp-3766	212	29	(	(	PUNCT
fnp-3766	212	30	fig	fig	NOUN
fnp-3766	212	31	.	.	PUNCT
fnp-3766	213	1	2c	2c	NUM
fnp-3766	213	2	and	and	CCONJ
fnp-3766	213	3	d	d	NOUN
fnp-3766	213	4	)	)	PUNCT
fnp-3766	213	5	.	.	PUNCT
fnp-3766	214	1	notably	notably	ADV
fnp-3766	214	2	,	,	PUNCT
fnp-3766	214	3	there	there	PRON
fnp-3766	214	4	was	be	VERB
fnp-3766	214	5	considerable	considerable	ADJ
fnp-3766	214	6	variation	variation	NOUN
fnp-3766	214	7	in	in	ADP
fnp-3766	214	8	the	the	DET
fnp-3766	214	9	levels	level	NOUN
fnp-3766	214	10	of	of	ADP
fnp-3766	214	11	aβ	aβ	PRON
fnp-3766	214	12	in	in	ADP
fnp-3766	214	13	these	these	DET
fnp-3766	214	14	seeded	seeded	ADJ
fnp-3766	214	15	animals	animal	NOUN
fnp-3766	214	16	,	,	PUNCT
fnp-3766	214	17	which	which	PRON
fnp-3766	214	18	rendered	render	VERB
fnp-3766	214	19	relatively	relatively	ADV
fnp-3766	214	20	few	few	ADJ
fnp-3766	214	21	indications	indication	NOUN
fnp-3766	214	22	of	of	ADP
fnp-3766	214	23	statistical	statistical	ADJ
fnp-3766	214	24	differences	difference	NOUN
fnp-3766	214	25	(	(	PUNCT
fnp-3766	214	26	fig	fig	NOUN
fnp-3766	214	27	.	.	PUNCT
fnp-3766	215	1	2e	2e	NOUN
fnp-3766	215	2	-	-	PUNCT
fnp-3766	215	3	h	h	NOUN
fnp-3766	215	4	)	)	PUNCT
fnp-3766	215	5	.	.	PUNCT
fnp-3766	216	1	for	for	ADP
fnp-3766	216	2	aβ40	aβ40	PROPN
fnp-3766	216	3	measures	measure	NOUN
fnp-3766	216	4	,	,	PUNCT
fnp-3766	216	5	the	the	DET
fnp-3766	216	6	only	only	ADJ
fnp-3766	216	7	instance	instance	NOUN
fnp-3766	216	8	in	in	ADP
fnp-3766	216	9	which	which	PRON
fnp-3766	216	10	the	the	DET
fnp-3766	216	11	seeded	seeded	ADJ
fnp-3766	216	12	mice	mouse	NOUN
fnp-3766	216	13	had	have	VERB
fnp-3766	216	14	levels	level	NOUN
fnp-3766	216	15	that	that	PRON
fnp-3766	216	16	were	be	AUX
fnp-3766	216	17	higher	high	ADJ
fnp-3766	216	18	than	than	ADP
fnp-3766	216	19	uninjected	uninjected	ADJ
fnp-3766	216	20	controls	control	NOUN
fnp-3766	216	21	,	,	PUNCT
fnp-3766	216	22	or	or	CCONJ
fnp-3766	216	23	mice	mouse	NOUN
fnp-3766	216	24	injected	inject	VERB
fnp-3766	216	25	with	with	ADP
fnp-3766	216	26	ndc	ndc	NOUN
fnp-3766	216	27	lysate	lysate	NOUN
fnp-3766	216	28	,	,	PUNCT
fnp-3766	216	29	were	be	AUX
fnp-3766	216	30	mice	mouse	NOUN
fnp-3766	216	31	seeded	seed	VERB
fnp-3766	216	32	by	by	ADP
fnp-3766	216	33	ad	ad	NOUN
fnp-3766	216	34	1	1	NUM
fnp-3766	216	35	(	(	PUNCT
fnp-3766	216	36	fig	fig	NOUN
fnp-3766	216	37	.	.	PUNCT
fnp-3766	217	1	2e	2e	NOUN
fnp-3766	217	2	,	,	PUNCT
fnp-3766	217	3	f	f	NOUN
fnp-3766	217	4	)	)	PUNCT
fnp-3766	217	5	.	.	PUNCT
fnp-3766	218	1	for	for	ADP
fnp-3766	218	2	measurements	measurement	NOUN
fnp-3766	218	3	of	of	ADP
fnp-3766	218	4	sds	sds	NOUN
fnp-3766	218	5	-	-	PUNCT
fnp-3766	218	6	soluble	soluble	ADJ
fnp-3766	218	7	aβ42	aβ42	PROPN
fnp-3766	218	8	,	,	PUNCT
fnp-3766	218	9	the	the	DET
fnp-3766	218	10	brains	brain	NOUN
fnp-3766	218	11	of	of	ADP
fnp-3766	218	12	mice	mouse	NOUN
fnp-3766	218	13	seeded	seed	VERB
fnp-3766	218	14	with	with	ADP
fnp-3766	218	15	ad	ad	NOUN
fnp-3766	218	16	1	1	NUM
fnp-3766	218	17	,	,	PUNCT
fnp-3766	218	18	2	2	NUM
fnp-3766	218	19	,	,	PUNCT
fnp-3766	218	20	and	and	CCONJ
fnp-3766	218	21	pa	pa	PROPN
fnp-3766	218	22	4	4	NUM
fnp-3766	218	23	were	be	AUX
fnp-3766	218	24	the	the	DET
fnp-3766	218	25	only	only	ADJ
fnp-3766	218	26	examples	example	NOUN
fnp-3766	218	27	in	in	ADP
fnp-3766	218	28	which	which	PRON
fnp-3766	218	29	the	the	DET
fnp-3766	218	30	levels	level	NOUN
fnp-3766	218	31	were	be	AUX
fnp-3766	218	32	statistically	statistically	ADV
fnp-3766	218	33	higher	high	ADJ
fnp-3766	218	34	than	than	ADP
fnp-3766	218	35	the	the	DET
fnp-3766	218	36	levels	level	NOUN
fnp-3766	218	37	in	in	ADP
fnp-3766	218	38	mice	mouse	NOUN
fnp-3766	218	39	seeded	seed	VERB
fnp-3766	218	40	with	with	ADP
fnp-3766	218	41	ndc	ndc	PROPN
fnp-3766	218	42	1	1	NUM
fnp-3766	218	43	and	and	CCONJ
fnp-3766	218	44	2	2	NUM
fnp-3766	218	45	,	,	PUNCT
fnp-3766	218	46	or	or	CCONJ
fnp-3766	218	47	uninjected	uninjected	ADJ
fnp-3766	218	48	mice	mouse	NOUN
fnp-3766	218	49	(	(	PUNCT
fnp-3766	218	50	fig	fig	NOUN
fnp-3766	218	51	.	.	PUNCT
fnp-3766	219	1	2	2	NUM
fnp-3766	219	2	g	g	NOUN
fnp-3766	219	3	)	)	PUNCT
fnp-3766	219	4	.	.	PUNCT
fnp-3766	220	1	in	in	ADP
fnp-3766	220	2	the	the	DET
fnp-3766	220	3	fa	fa	NOUN
fnp-3766	220	4	-	-	ADJ
fnp-3766	220	5	soluble	soluble	ADJ
fnp-3766	220	6	fractions	fraction	NOUN
fnp-3766	220	7	,	,	PUNCT
fnp-3766	220	8	only	only	ADV
fnp-3766	220	9	the	the	DET
fnp-3766	220	10	ad	ad	NOUN
fnp-3766	220	11	lysates	lysate	NOUN
fnp-3766	220	12	possessed	possess	VERB
fnp-3766	220	13	higher	high	ADJ
fnp-3766	220	14	levels	level	NOUN
fnp-3766	220	15	of	of	ADP
fnp-3766	220	16	aβ42	aβ42	PROPN
fnp-3766	220	17	than	than	ADP
fnp-3766	220	18	the	the	DET
fnp-3766	220	19	brains	brain	NOUN
fnp-3766	220	20	of	of	ADP
fnp-3766	220	21	mice	mouse	NOUN
fnp-3766	220	22	seeded	seed	VERB
fnp-3766	220	23	with	with	ADP
fnp-3766	220	24	the	the	DET
fnp-3766	220	25	two	two	NUM
fnp-3766	220	26	ndc	ndc	NOUN
fnp-3766	220	27	lysates	lysate	NOUN
fnp-3766	220	28	or	or	CCONJ
fnp-3766	220	29	uninjected	uninjected	ADJ
fnp-3766	220	30	mice	mouse	NOUN
fnp-3766	220	31	(	(	PUNCT
fnp-3766	220	32	fig	fig	NOUN
fnp-3766	220	33	.	.	PUNCT
fnp-3766	221	1	2h	2h	NUM
fnp-3766	221	2	)	)	PUNCT
fnp-3766	221	3	.	.	PUNCT
fnp-3766	222	1	collectively	collectively	ADV
fnp-3766	222	2	,	,	PUNCT
fnp-3766	222	3	these	these	DET
fnp-3766	222	4	findings	finding	NOUN
fnp-3766	222	5	demonstrated	demonstrate	VERB
fnp-3766	222	6	that	that	SCONJ
fnp-3766	222	7	both	both	DET
fnp-3766	222	8	ad	ad	NOUN
fnp-3766	222	9	and	and	CCONJ
fnp-3766	222	10	pa	pa	PROPN
fnp-3766	222	11	brains	brain	NOUN
fnp-3766	222	12	have	have	VERB
fnp-3766	222	13	the	the	DET
fnp-3766	222	14	potential	potential	NOUN
fnp-3766	222	15	to	to	PART
fnp-3766	222	16	seed	seed	VERB
fnp-3766	222	17	diffuse	diffuse	NOUN
fnp-3766	222	18	aβ	aβ	ADP
fnp-3766	222	19	pathology	pathology	NOUN
fnp-3766	222	20	,	,	PUNCT
fnp-3766	222	21	with	with	ADP
fnp-3766	222	22	the	the	DET
fnp-3766	222	23	ad	ad	NOUN
fnp-3766	222	24	brains	brain	NOUN
fnp-3766	222	25	appearing	appear	VERB
fnp-3766	222	26	to	to	PART
fnp-3766	222	27	be	be	AUX
fnp-3766	222	28	slightly	slightly	ADV
fnp-3766	222	29	more	more	ADV
fnp-3766	222	30	potent	potent	ADJ
fnp-3766	222	31	.	.	PUNCT
fnp-3766	223	1	fig	fig	NOUN
fnp-3766	223	2	.	.	PUNCT
fnp-3766	224	1	2	2	NUM
fnp-3766	224	2	biochemical	biochemical	ADJ
fnp-3766	224	3	analysis	analysis	NOUN
fnp-3766	224	4	of	of	ADP
fnp-3766	224	5	sequentially	sequentially	ADV
fnp-3766	224	6	extracted	extract	VERB
fnp-3766	224	7	aβ42	aβ42	PROPN
fnp-3766	224	8	and	and	CCONJ
fnp-3766	224	9	aβ40	aβ40	PROPN
fnp-3766	224	10	levels	level	NOUN
fnp-3766	224	11	by	by	ADP
fnp-3766	224	12	end	end	NOUN
fnp-3766	224	13	-	-	PUNCT
fnp-3766	224	14	specific	specific	ADJ
fnp-3766	224	15	sandwich	sandwich	NOUN
fnp-3766	224	16	elisa	elisa	NOUN
fnp-3766	224	17	.	.	PUNCT
fnp-3766	225	1	prp.appsi/tau-p301l	prp.appsi/tau-p301l	NOUN
fnp-3766	225	2	and	and	CCONJ
fnp-3766	225	3	prp.appsi	prp.appsi	NUM
fnp-3766	225	4	mice	mouse	NOUN
fnp-3766	225	5	were	be	AUX
fnp-3766	225	6	seeded	seed	VERB
fnp-3766	225	7	by	by	ADP
fnp-3766	225	8	ad	ad	NOUN
fnp-3766	225	9	,	,	PUNCT
fnp-3766	225	10	pa	pa	PROPN
fnp-3766	225	11	,	,	PUNCT
fnp-3766	225	12	or	or	CCONJ
fnp-3766	225	13	ndc	ndc	NOUN
fnp-3766	225	14	lysate	lysate	NOUN
fnp-3766	225	15	at	at	ADP
fnp-3766	225	16	p0	p0	NOUN
fnp-3766	225	17	and	and	CCONJ
fnp-3766	225	18	aged	aged	ADJ
fnp-3766	225	19	12	12	NUM
fnp-3766	225	20	months	month	NOUN
fnp-3766	225	21	.	.	PUNCT
fnp-3766	226	1	(	(	PUNCT
fnp-3766	226	2	a	a	PRON
fnp-3766	226	3	,	,	PUNCT
fnp-3766	226	4	e	e	NOUN
fnp-3766	226	5	)	)	PUNCT
fnp-3766	226	6	2	2	NUM
fnp-3766	226	7	%	%	NOUN
fnp-3766	226	8	sds	sds	NOUN
fnp-3766	226	9	-	-	PUNCT
fnp-3766	226	10	extracted	extract	VERB
fnp-3766	226	11	aβ40	aβ40	PROPN
fnp-3766	226	12	,	,	PUNCT
fnp-3766	226	13	(	(	PUNCT
fnp-3766	226	14	b	b	X
fnp-3766	226	15	,	,	PUNCT
fnp-3766	226	16	f	f	X
fnp-3766	226	17	)	)	PUNCT
fnp-3766	226	18	70	70	NUM
fnp-3766	226	19	%	%	NOUN
fnp-3766	226	20	formic	formic	NOUN
fnp-3766	226	21	acid	acid	NOUN
fnp-3766	226	22	aβ40	aβ40	PROPN
fnp-3766	226	23	,	,	PUNCT
fnp-3766	226	24	(	(	PUNCT
fnp-3766	226	25	c	c	X
fnp-3766	226	26	,	,	PUNCT
fnp-3766	226	27	g	g	NOUN
fnp-3766	226	28	)	)	PUNCT
fnp-3766	226	29	2	2	NUM
fnp-3766	226	30	%	%	NOUN
fnp-3766	226	31	sds	sds	NOUN
fnp-3766	226	32	-	-	PUNCT
fnp-3766	226	33	extracted	extract	VERB
fnp-3766	226	34	aβ42	aβ42	PROPN
fnp-3766	226	35	,	,	PUNCT
fnp-3766	226	36	and	and	CCONJ
fnp-3766	226	37	(	(	PUNCT
fnp-3766	226	38	d	d	NOUN
fnp-3766	226	39	,	,	PUNCT
fnp-3766	226	40	h	h	NOUN
fnp-3766	226	41	)	)	PUNCT
fnp-3766	226	42	70	70	NUM
fnp-3766	226	43	%	%	NOUN
fnp-3766	226	44	formic	formic	ADJ
fnp-3766	226	45	acid	acid	NOUN
fnp-3766	226	46	aβ42	aβ42	PROPN
fnp-3766	226	47	.	.	PUNCT
fnp-3766	227	1	data	datum	NOUN
fnp-3766	227	2	plotted	plot	VERB
fnp-3766	227	3	as	as	ADP
fnp-3766	227	4	scatter	scatter	NOUN
fnp-3766	227	5	dot	dot	NOUN
fnp-3766	227	6	plot	plot	NOUN
fnp-3766	227	7	of	of	ADP
fnp-3766	227	8	prp.appsi/tau-p301l	prp.appsi/tau-p301l	NOUN
fnp-3766	227	9	(	(	PUNCT
fnp-3766	227	10	square	square	NOUN
fnp-3766	227	11	)	)	PUNCT
fnp-3766	227	12	and	and	CCONJ
fnp-3766	227	13	prp.appsi	prp.appsi	PROPN
fnp-3766	227	14	(	(	PUNCT
fnp-3766	227	15	circle	circle	NOUN
fnp-3766	227	16	)	)	PUNCT
fnp-3766	227	17	±	±	NOUN
fnp-3766	227	18	standard	standard	NOUN
fnp-3766	227	19	error	error	NOUN
fnp-3766	227	20	of	of	ADP
fnp-3766	227	21	the	the	DET
fnp-3766	227	22	mean	mean	NOUN
fnp-3766	227	23	.	.	PUNCT
fnp-3766	228	1	the	the	DET
fnp-3766	228	2	number	number	NOUN
fnp-3766	228	3	of	of	ADP
fnp-3766	228	4	prp.appsi/tau-p301l	prp.appsi/tau-p301l	NOUN
fnp-3766	228	5	or	or	CCONJ
fnp-3766	228	6	prp.appsi	prp.appsi	NUM
fnp-3766	228	7	mice	mouse	NOUN
fnp-3766	228	8	injected	inject	VERB
fnp-3766	228	9	with	with	ADP
fnp-3766	228	10	each	each	DET
fnp-3766	228	11	lysate	lysate	NOUN
fnp-3766	228	12	,	,	PUNCT
fnp-3766	228	13	respectively	respectively	ADV
fnp-3766	228	14	,	,	PUNCT
fnp-3766	228	15	were	be	AUX
fnp-3766	228	16	as	as	SCONJ
fnp-3766	228	17	follows	follow	VERB
fnp-3766	228	18	:	:	PUNCT
fnp-3766	228	19	ad	ad	NOUN
fnp-3766	228	20	1	1	NUM
fnp-3766	228	21	:	:	PUNCT
fnp-3766	228	22	n=5	n=5	NUM
fnp-3766	228	23	,	,	PUNCT
fnp-3766	228	24	n=4	n=4	NUM
fnp-3766	228	25	;	;	PUNCT
fnp-3766	228	26	ad	ad	NOUN
fnp-3766	228	27	2	2	NUM
fnp-3766	228	28	:	:	PUNCT
fnp-3766	228	29	n=6	n=6	NUM
fnp-3766	228	30	,	,	PUNCT
fnp-3766	228	31	n=5	n=5	PROPN
fnp-3766	228	32	;	;	PUNCT
fnp-3766	228	33	pa	pa	PROPN
fnp-3766	228	34	1	1	NUM
fnp-3766	228	35	:	:	PUNCT
fnp-3766	228	36	n=5	n=5	NUM
fnp-3766	228	37	,	,	PUNCT
fnp-3766	228	38	n=4	n=4	NUM
fnp-3766	228	39	;	;	PUNCT
fnp-3766	228	40	pa	pa	PROPN
fnp-3766	228	41	2	2	NUM
fnp-3766	228	42	:	:	PUNCT
fnp-3766	228	43	n=4	n=4	NOUN
fnp-3766	228	44	,	,	PUNCT
fnp-3766	228	45	n=5	n=5	PROPN
fnp-3766	228	46	;	;	PUNCT
fnp-3766	228	47	pa	pa	PROPN
fnp-3766	228	48	3	3	NUM
fnp-3766	228	49	:	:	PUNCT
fnp-3766	228	50	n=5	n=5	NUM
fnp-3766	228	51	,	,	PUNCT
fnp-3766	228	52	n=4	n=4	NUM
fnp-3766	228	53	;	;	PUNCT
fnp-3766	228	54	pa	pa	PROPN
fnp-3766	228	55	4	4	NUM
fnp-3766	228	56	:	:	PUNCT
fnp-3766	228	57	n=3	n=3	NOUN
fnp-3766	228	58	,	,	PUNCT
fnp-3766	228	59	n=5	n=5	NUM
fnp-3766	228	60	;	;	PUNCT
fnp-3766	228	61	ndc	ndc	PROPN
fnp-3766	228	62	1	1	NUM
fnp-3766	228	63	:	:	PUNCT
fnp-3766	228	64	n=5	n=5	NUM
fnp-3766	228	65	,	,	PUNCT
fnp-3766	228	66	n=4	n=4	NUM
fnp-3766	228	67	;	;	PUNCT
fnp-3766	228	68	ndc	ndc	PROPN
fnp-3766	228	69	2	2	NUM
fnp-3766	228	70	:	:	PUNCT
fnp-3766	228	71	n=5	n=5	NUM
fnp-3766	228	72	,	,	PUNCT
fnp-3766	228	73	n=5	n=5	PRON
fnp-3766	228	74	;	;	PUNCT
fnp-3766	228	75	uninjected	uninjected	ADJ
fnp-3766	228	76	:	:	PUNCT
fnp-3766	228	77	n=5	n=5	NOUN
fnp-3766	228	78	,	,	PUNCT
fnp-3766	228	79	n=3	n=3	PRON
fnp-3766	228	80	.	.	PUNCT
fnp-3766	229	1	aβ42	aβ42	PROPN
fnp-3766	229	2	and	and	CCONJ
fnp-3766	229	3	aβ40	aβ40	PROPN
fnp-3766	229	4	levels	level	NOUN
fnp-3766	229	5	were	be	AUX
fnp-3766	229	6	quantified	quantify	VERB
fnp-3766	229	7	with	with	ADP
fnp-3766	229	8	corresponding	correspond	VERB
fnp-3766	229	9	one	one	NUM
fnp-3766	229	10	-	-	PUNCT
fnp-3766	229	11	way	way	NOUN
fnp-3766	229	12	anova	anova	X
fnp-3766	229	13	with	with	ADP
fnp-3766	229	14	multiple	multiple	ADJ
fnp-3766	229	15	comparisons	comparison	NOUN
fnp-3766	229	16	test	test	NOUN
fnp-3766	229	17	(	(	PUNCT
fnp-3766	229	18	ns	ns	INTJ
fnp-3766	229	19	,	,	PUNCT
fnp-3766	229	20	p	p	X
fnp-3766	229	21	>	>	X
fnp-3766	229	22	0.05	0.05	NUM
fnp-3766	229	23	;	;	PUNCT
fnp-3766	229	24	*	*	X
fnp-3766	229	25	,	,	PUNCT
fnp-3766	229	26	p	p	X
fnp-3766	229	27	≤	≤	NOUN
fnp-3766	229	28	0.05	0.05	NUM
fnp-3766	229	29	;	;	PUNCT
fnp-3766	229	30	*	*	PUNCT
fnp-3766	230	1	*	*	PUNCT
fnp-3766	230	2	,	,	PUNCT
fnp-3766	230	3	p	p	NOUN
fnp-3766	230	4	≤	≤	NOUN
fnp-3766	230	5	0.01	0.01	NUM
fnp-3766	230	6	;	;	PUNCT
fnp-3766	231	1	*	*	PUNCT
fnp-3766	231	2	*	*	PUNCT
fnp-3766	231	3	*	*	PUNCT
fnp-3766	231	4	,	,	PUNCT
fnp-3766	231	5	p	p	NOUN
fnp-3766	231	6	≤	≤	NOUN
fnp-3766	231	7	0.001	0.001	NUM
fnp-3766	231	8	;	;	PUNCT
fnp-3766	232	1	*	*	PUNCT
fnp-3766	232	2	*	*	PUNCT
fnp-3766	232	3	*	*	PUNCT
fnp-3766	232	4	*	*	PUNCT
fnp-3766	232	5	,	,	PUNCT
fnp-3766	232	6	p	p	ADJ
fnp-3766	232	7	≤	≤	NOUN
fnp-3766	232	8	0.0001	0.0001	NUM
fnp-3766	232	9	)	)	PUNCT
fnp-3766	232	10	.	.	PUNCT
fnp-3766	233	1	to	to	PART
fnp-3766	233	2	determine	determine	VERB
fnp-3766	233	3	whether	whether	SCONJ
fnp-3766	233	4	the	the	DET
fnp-3766	233	5	injection	injection	NOUN
fnp-3766	233	6	of	of	ADP
fnp-3766	233	7	these	these	DET
fnp-3766	233	8	lysates	lysate	NOUN
fnp-3766	233	9	into	into	ADP
fnp-3766	233	10	the	the	DET
fnp-3766	233	11	brains	brain	NOUN
fnp-3766	233	12	of	of	ADP
fnp-3766	233	13	newborn	newborn	ADJ
fnp-3766	233	14	prp.appsi/itau-p301l	prp.appsi/itau-p301l	NOUN
fnp-3766	233	15	mice	mouse	NOUN
fnp-3766	233	16	also	also	ADV
fnp-3766	233	17	induced	induce	VERB
fnp-3766	233	18	tau	tau	PROPN
fnp-3766	233	19	pathology	pathology	NOUN
fnp-3766	233	20	,	,	PUNCT
fnp-3766	233	21	we	we	PRON
fnp-3766	233	22	stained	stain	VERB
fnp-3766	233	23	the	the	DET
fnp-3766	233	24	brains	brain	NOUN
fnp-3766	233	25	of	of	ADP
fnp-3766	233	26	the	the	DET
fnp-3766	233	27	seeded	seeded	ADJ
fnp-3766	233	28	animals	animal	NOUN
fnp-3766	233	29	with	with	ADP
fnp-3766	233	30	antibodies	antibody	NOUN
fnp-3766	233	31	specific	specific	ADJ
fnp-3766	233	32	for	for	ADP
fnp-3766	233	33	phosphorylated	phosphorylate	VERB
fnp-3766	233	34	tau	tau	PROPN
fnp-3766	233	35	(	(	PUNCT
fnp-3766	233	36	at8	at8	PROPN
fnp-3766	233	37	)	)	PUNCT
fnp-3766	233	38	and	and	CCONJ
fnp-3766	233	39	misfolded	misfolde	VERB
fnp-3766	233	40	tau	tau	PROPN
fnp-3766	233	41	(	(	PUNCT
fnp-3766	233	42	mc1	mc1	PROPN
fnp-3766	233	43	)	)	PUNCT
fnp-3766	233	44	.	.	PUNCT
fnp-3766	234	1	immunostaining	immunostaine	VERB
fnp-3766	234	2	with	with	ADP
fnp-3766	234	3	the	the	DET
fnp-3766	234	4	antibody	antibody	NOUN
fnp-3766	234	5	cp27	cp27	PROPN
fnp-3766	234	6	,	,	PUNCT
fnp-3766	234	7	which	which	PRON
fnp-3766	234	8	is	be	AUX
fnp-3766	234	9	specific	specific	ADJ
fnp-3766	234	10	for	for	ADP
fnp-3766	234	11	human	human	PROPN
fnp-3766	234	12	tau	tau	PROPN
fnp-3766	234	13	,	,	PUNCT
fnp-3766	234	14	confirmed	confirm	VERB
fnp-3766	234	15	the	the	DET
fnp-3766	234	16	presence	presence	NOUN
fnp-3766	234	17	of	of	ADP
fnp-3766	234	18	human	human	PROPN
fnp-3766	234	19	p301l	p301l	PROPN
fnp-3766	234	20	tau	tau	PROPN
fnp-3766	234	21	in	in	ADP
fnp-3766	234	22	the	the	DET
fnp-3766	234	23	bigenic	bigenic	ADJ
fnp-3766	234	24	mice	mouse	NOUN
fnp-3766	234	25	,	,	PUNCT
fnp-3766	234	26	but	but	CCONJ
fnp-3766	234	27	we	we	PRON
fnp-3766	234	28	observed	observe	VERB
fnp-3766	234	29	no	no	DET
fnp-3766	234	30	obvious	obvious	ADJ
fnp-3766	234	31	reactivity	reactivity	NOUN
fnp-3766	234	32	with	with	ADP
fnp-3766	234	33	at8	at8	PROPN
fnp-3766	234	34	or	or	CCONJ
fnp-3766	234	35	mc1	mc1	PROPN
fnp-3766	234	36	antibodies	antibodie	VERB
fnp-3766	234	37	(	(	PUNCT
fnp-3766	234	38	fig	fig	NOUN
fnp-3766	234	39	.	.	PUNCT
fnp-3766	234	40	s9	s9	NOUN
fnp-3766	234	41	)	)	PUNCT
fnp-3766	234	42	.	.	PUNCT
fnp-3766	235	1	to	to	PART
fnp-3766	235	2	determine	determine	VERB
fnp-3766	235	3	if	if	SCONJ
fnp-3766	235	4	the	the	DET
fnp-3766	235	5	induction	induction	NOUN
fnp-3766	235	6	of	of	ADP
fnp-3766	235	7	amyloid	amyloid	NOUN
fnp-3766	235	8	would	would	AUX
fnp-3766	235	9	secondarily	secondarily	ADV
fnp-3766	235	10	induce	induce	VERB
fnp-3766	235	11	αsyn	αsyn	ADJ
fnp-3766	235	12	pathology	pathology	NOUN
fnp-3766	235	13	,	,	PUNCT
fnp-3766	235	14	we	we	PRON
fnp-3766	235	15	examined	examine	VERB
fnp-3766	235	16	the	the	DET
fnp-3766	235	17	seeding	seed	VERB
fnp-3766	235	18	activity	activity	NOUN
fnp-3766	235	19	of	of	ADP
fnp-3766	235	20	individuals	individual	NOUN
fnp-3766	235	21	with	with	ADP
fnp-3766	235	22	ad	ad	NOUN
fnp-3766	235	23	and	and	CCONJ
fnp-3766	235	24	lbd	lbd	PROPN
fnp-3766	235	25	pathology	pathology	PROPN
fnp-3766	235	26	.	.	PUNCT
fnp-3766	236	1	to	to	PART
fnp-3766	236	2	characterize	characterize	VERB
fnp-3766	236	3	the	the	DET
fnp-3766	236	4	pathology	pathology	NOUN
fnp-3766	236	5	of	of	ADP
fnp-3766	236	6	these	these	DET
fnp-3766	236	7	ad	ad	NOUN
fnp-3766	236	8	,	,	PUNCT
fnp-3766	236	9	ad	ad	NOUN
fnp-3766	236	10	/	/	SYM
fnp-3766	236	11	lbd	lbd	PROPN
fnp-3766	236	12	,	,	PUNCT
fnp-3766	236	13	and	and	CCONJ
fnp-3766	236	14	ndc	ndc	NOUN
fnp-3766	236	15	brains	brain	NOUN
fnp-3766	236	16	,	,	PUNCT
fnp-3766	236	17	we	we	PRON
fnp-3766	236	18	stained	stain	VERB
fnp-3766	236	19	sections	section	NOUN
fnp-3766	236	20	with	with	ADP
fnp-3766	236	21	a	a	DET
fnp-3766	236	22	pan	pan	ADJ
fnp-3766	236	23	-	-	ADJ
fnp-3766	236	24	aβ	aβ	ADJ
fnp-3766	236	25	antibody	antibody	NOUN
fnp-3766	236	26	(	(	PUNCT
fnp-3766	236	27	fig	fig	NOUN
fnp-3766	236	28	.	.	PUNCT
fnp-3766	237	1	3a	3a	NUM
fnp-3766	237	2	)	)	PUNCT
fnp-3766	237	3	,	,	PUNCT
fnp-3766	237	4	thio	thio	NOUN
fnp-3766	237	5	-	-	SYM
fnp-3766	237	6	s	s	X
fnp-3766	237	7	(	(	PUNCT
fnp-3766	237	8	fig	fig	NOUN
fnp-3766	237	9	.	.	PUNCT
fnp-3766	238	1	3b	3b	NUM
fnp-3766	238	2	)	)	PUNCT
fnp-3766	238	3	,	,	PUNCT
fnp-3766	238	4	αsyn	αsyn	ADJ
fnp-3766	238	5	antibody	antibody	NOUN
fnp-3766	238	6	(	(	PUNCT
fnp-3766	238	7	fig	fig	NOUN
fnp-3766	238	8	.	.	PUNCT
fnp-3766	239	1	3c	3c	NUM
fnp-3766	239	2	)	)	PUNCT
fnp-3766	239	3	,	,	PUNCT
fnp-3766	239	4	and	and	CCONJ
fnp-3766	239	5	a	a	DET
fnp-3766	239	6	phospho	phospho	NOUN
fnp-3766	239	7	-	-	PUNCT
fnp-3766	239	8	specific	specific	ADJ
fnp-3766	239	9	tau	tau	NOUN
fnp-3766	239	10	antibody	antibody	NOUN
fnp-3766	239	11	(	(	PUNCT
fnp-3766	239	12	fig	fig	NOUN
fnp-3766	239	13	.	.	PUNCT
fnp-3766	239	14	3d	3d	NUM
fnp-3766	239	15	)	)	PUNCT
fnp-3766	239	16	.	.	PUNCT
fnp-3766	240	1	both	both	DET
fnp-3766	240	2	ad	ad	NOUN
fnp-3766	240	3	3	3	NUM
fnp-3766	240	4	and	and	CCONJ
fnp-3766	240	5	4	4	NUM
fnp-3766	240	6	contained	contain	VERB
fnp-3766	240	7	numerous	numerous	ADJ
fnp-3766	240	8	amyloid	amyloid	NOUN
fnp-3766	240	9	deposits	deposit	NOUN
fnp-3766	240	10	that	that	PRON
fnp-3766	240	11	were	be	AUX
fnp-3766	240	12	compact	compact	ADJ
fnp-3766	240	13	and	and	CCONJ
fnp-3766	240	14	thio	thio	NOUN
fnp-3766	240	15	-	-	PUNCT
fnp-3766	240	16	s	s	NOUN
fnp-3766	240	17	positive	positive	ADJ
fnp-3766	240	18	(	(	PUNCT
fnp-3766	240	19	fig	fig	NOUN
fnp-3766	240	20	.	.	PUNCT
fnp-3766	241	1	3a	3a	NUM
fnp-3766	241	2	,	,	PUNCT
fnp-3766	241	3	b	b	NOUN
fnp-3766	241	4	)	)	PUNCT
fnp-3766	241	5	,	,	PUNCT
fnp-3766	241	6	had	have	VERB
fnp-3766	241	7	widespread	widespread	ADJ
fnp-3766	241	8	tau	tau	INTJ
fnp-3766	241	9	positive	positive	ADJ
fnp-3766	241	10	inclusions	inclusion	NOUN
fnp-3766	241	11	(	(	PUNCT
fnp-3766	241	12	fig	fig	NOUN
fnp-3766	241	13	.	.	PUNCT
fnp-3766	241	14	3d	3d	NUM
fnp-3766	241	15	)	)	PUNCT
fnp-3766	241	16	,	,	PUNCT
fnp-3766	241	17	and	and	CCONJ
fnp-3766	241	18	lacked	lack	VERB
fnp-3766	241	19	αsyn	αsyn	ADJ
fnp-3766	241	20	pathology	pathology	NOUN
fnp-3766	241	21	(	(	PUNCT
fnp-3766	241	22	fig	fig	NOUN
fnp-3766	241	23	.	.	PUNCT
fnp-3766	242	1	3c	3c	NUM
fnp-3766	242	2	)	)	PUNCT
fnp-3766	242	3	.	.	PUNCT
fnp-3766	243	1	ad	ad	NOUN
fnp-3766	243	2	3	3	NUM
fnp-3766	243	3	showed	show	VERB
fnp-3766	243	4	striking	striking	ADJ
fnp-3766	243	5	thio	thio	NOUN
fnp-3766	243	6	-	-	PUNCT
fnp-3766	243	7	s	s	PART
fnp-3766	243	8	positive	positive	ADJ
fnp-3766	243	9	amyloid	amyloid	NOUN
fnp-3766	243	10	staining	stain	VERB
fnp-3766	243	11	surrounding	surround	VERB
fnp-3766	243	12	vessels	vessel	NOUN
fnp-3766	243	13	,	,	PUNCT
fnp-3766	243	14	consistent	consistent	ADJ
fnp-3766	243	15	with	with	ADP
fnp-3766	243	16	a	a	DET
fnp-3766	243	17	caa	caa	NOUN
fnp-3766	243	18	score	score	NOUN
fnp-3766	243	19	of	of	ADP
fnp-3766	243	20	3	3	NUM
fnp-3766	243	21	+	+	CCONJ
fnp-3766	243	22	(	(	PUNCT
fnp-3766	243	23	fig	fig	NOUN
fnp-3766	243	24	.	.	PUNCT
fnp-3766	244	1	3b	3b	NUM
fnp-3766	244	2	,	,	PUNCT
fnp-3766	244	3	table	table	NOUN
fnp-3766	244	4	1	1	NUM
fnp-3766	244	5	)	)	PUNCT
fnp-3766	244	6	.	.	PUNCT
fnp-3766	245	1	we	we	PRON
fnp-3766	245	2	also	also	ADV
fnp-3766	245	3	observed	observe	VERB
fnp-3766	245	4	caa	caa	NOUN
fnp-3766	245	5	staining	stain	VERB
fnp-3766	245	6	with	with	ADP
fnp-3766	245	7	ad	ad	NOUN
fnp-3766	245	8	/	/	SYM
fnp-3766	245	9	lbd	lbd	PROPN
fnp-3766	245	10	1	1	NUM
fnp-3766	245	11	(	(	PUNCT
fnp-3766	245	12	fig	fig	NOUN
fnp-3766	245	13	.	.	PUNCT
fnp-3766	246	1	3b	3b	NUM
fnp-3766	246	2	)	)	PUNCT
fnp-3766	246	3	.	.	PUNCT
fnp-3766	247	1	the	the	DET
fnp-3766	247	2	ad	ad	NOUN
fnp-3766	247	3	/	/	SYM
fnp-3766	247	4	lbd	lbd	PROPN
fnp-3766	247	5	cases	case	NOUN
fnp-3766	247	6	showed	show	VERB
fnp-3766	247	7	modest	modest	ADJ
fnp-3766	247	8	aβ	aβ	NOUN
fnp-3766	247	9	pathology	pathology	NOUN
fnp-3766	247	10	with	with	ADP
fnp-3766	247	11	some	some	DET
fnp-3766	247	12	αsyn	αsyn	ADJ
fnp-3766	247	13	pathology	pathology	NOUN
fnp-3766	247	14	and	and	CCONJ
fnp-3766	247	15	sparse	sparse	VERB
fnp-3766	247	16	tau	tau	NOUN
fnp-3766	247	17	deposition	deposition	NOUN
fnp-3766	247	18	(	(	PUNCT
fnp-3766	247	19	fig	fig	NOUN
fnp-3766	247	20	.	.	PUNCT
fnp-3766	248	1	3a	3a	NUM
fnp-3766	248	2	,	,	PUNCT
fnp-3766	248	3	c	c	X
fnp-3766	248	4	,	,	PUNCT
fnp-3766	248	5	d	d	NOUN
fnp-3766	248	6	)	)	PUNCT
fnp-3766	248	7	.	.	PUNCT
fnp-3766	249	1	ndc	ndc	PROPN
fnp-3766	249	2	3	3	NUM
fnp-3766	249	3	contained	contain	VERB
fnp-3766	249	4	some	some	DET
fnp-3766	249	5	amyloid	amyloid	NOUN
fnp-3766	249	6	pathology	pathology	NOUN
fnp-3766	249	7	,	,	PUNCT
fnp-3766	249	8	but	but	CCONJ
fnp-3766	249	9	both	both	PRON
fnp-3766	249	10	lacked	lack	VERB
fnp-3766	249	11	αsyn	αsyn	NOUN
fnp-3766	249	12	and	and	CCONJ
fnp-3766	249	13	tau	tau	PROPN
fnp-3766	249	14	pathology	pathology	NOUN
fnp-3766	249	15	(	(	PUNCT
fnp-3766	249	16	fig	fig	NOUN
fnp-3766	249	17	.	.	PUNCT
fnp-3766	250	1	3	3	NUM
fnp-3766	250	2	)	)	PUNCT
fnp-3766	250	3	.	.	PUNCT
fnp-3766	251	1	fig	fig	NOUN
fnp-3766	251	2	.	.	PUNCT
fnp-3766	252	1	3	3	NUM
fnp-3766	252	2	characterization	characterization	NOUN
fnp-3766	252	3	of	of	ADP
fnp-3766	252	4	ad	ad	NOUN
fnp-3766	252	5	,	,	PUNCT
fnp-3766	252	6	ad	ad	NOUN
fnp-3766	252	7	/	/	SYM
fnp-3766	252	8	lbd	lbd	PROPN
fnp-3766	252	9	,	,	PUNCT
fnp-3766	252	10	and	and	CCONJ
fnp-3766	252	11	control	control	NOUN
fnp-3766	252	12	cases	case	NOUN
fnp-3766	252	13	.	.	PUNCT
fnp-3766	253	1	representative	representative	ADJ
fnp-3766	253	2	image	image	NOUN
fnp-3766	253	3	from	from	ADP
fnp-3766	253	4	the	the	DET
fnp-3766	253	5	cortex	cortex	NOUN
fnp-3766	253	6	of	of	ADP
fnp-3766	253	7	2	2	NUM
fnp-3766	253	8	ad	ad	NOUN
fnp-3766	253	9	cases	case	NOUN
fnp-3766	253	10	,	,	PUNCT
fnp-3766	253	11	2	2	NUM
fnp-3766	253	12	ad	ad	NOUN
fnp-3766	253	13	/	/	SYM
fnp-3766	253	14	lbd	lbd	NOUN
fnp-3766	253	15	cases	case	NOUN
fnp-3766	253	16	,	,	PUNCT
fnp-3766	253	17	and	and	CCONJ
fnp-3766	253	18	2	2	NUM
fnp-3766	253	19	ndc	ndc	NOUN
fnp-3766	253	20	cases	case	NOUN
fnp-3766	253	21	stained	stain	VERB
fnp-3766	253	22	with	with	ADP
fnp-3766	253	23	(	(	PUNCT
fnp-3766	253	24	a	a	PRON
fnp-3766	253	25	)	)	PUNCT
fnp-3766	253	26	biotinylated	biotinylate	VERB
fnp-3766	253	27	anti	anti	ADJ
fnp-3766	253	28	-	-	ADJ
fnp-3766	253	29	aβ	aβ	ADJ
fnp-3766	253	30	mab	mab	PROPN
fnp-3766	253	31	33.1.1	33.1.1	NUM
fnp-3766	253	32	(	(	PUNCT
fnp-3766	253	33	anti	anti	ADJ
fnp-3766	253	34	-	-	ADJ
fnp-3766	253	35	aβ	aβ	ADJ
fnp-3766	253	36	1	1	NUM
fnp-3766	253	37	-	-	NUM
fnp-3766	253	38	16	16	NUM
fnp-3766	253	39	)	)	PUNCT
fnp-3766	253	40	.	.	PUNCT
fnp-3766	254	1	scale	scale	NOUN
fnp-3766	254	2	bar	bar	NOUN
fnp-3766	254	3	:	:	PUNCT
fnp-3766	254	4	100	100	NUM
fnp-3766	254	5	μm	μm	NUM
fnp-3766	254	6	,	,	PUNCT
fnp-3766	254	7	(	(	PUNCT
fnp-3766	254	8	b	b	NOUN
fnp-3766	254	9	)	)	PUNCT
fnp-3766	254	10	thio	thio	NOUN
fnp-3766	254	11	-	-	PUNCT
fnp-3766	254	12	s.	s.	PROPN
fnp-3766	254	13	scale	scale	NOUN
fnp-3766	254	14	bar	bar	NOUN
fnp-3766	254	15	:	:	PUNCT
fnp-3766	254	16	50	50	NUM
fnp-3766	254	17	μm	μm	NOUN
fnp-3766	254	18	,	,	PUNCT
fnp-3766	254	19	(	(	PUNCT
fnp-3766	254	20	c	c	NOUN
fnp-3766	254	21	)	)	PUNCT
fnp-3766	254	22	anti	anti	ADJ
fnp-3766	254	23	-	-	ADJ
fnp-3766	254	24	αsyn	αsyn	ADJ
fnp-3766	254	25	mab	mab	NOUN
fnp-3766	254	26	9c10	9c10	NUM
fnp-3766	254	27	(	(	PUNCT
fnp-3766	254	28	anti	anti	X
fnp-3766	254	29	αsyn	αsyn	NOUN
fnp-3766	254	30	2	2	NUM
fnp-3766	254	31	-	-	SYM
fnp-3766	254	32	21	21	NUM
fnp-3766	254	33	)	)	PUNCT
fnp-3766	254	34	.	.	PUNCT
fnp-3766	255	1	arrowheads	arrowhead	NOUN
fnp-3766	255	2	depict	depict	VERB
fnp-3766	255	3	lewy	lewy	PROPN
fnp-3766	255	4	bodies	body	NOUN
fnp-3766	255	5	.	.	PUNCT
fnp-3766	256	1	scale	scale	NOUN
fnp-3766	256	2	bar	bar	NOUN
fnp-3766	256	3	:	:	PUNCT
fnp-3766	256	4	100	100	NUM
fnp-3766	256	5	μm	μm	NUM
fnp-3766	256	6	,	,	PUNCT
fnp-3766	256	7	and	and	CCONJ
fnp-3766	256	8	anti	anti	ADJ
fnp-3766	256	9	-	-	ADJ
fnp-3766	256	10	ptau	ptau	ADJ
fnp-3766	256	11	mab	mab	NOUN
fnp-3766	256	12	7f2	7f2	NUM
fnp-3766	256	13	(	(	PUNCT
fnp-3766	256	14	pthr205	pthr205	NOUN
fnp-3766	256	15	)	)	PUNCT
fnp-3766	256	16	.	.	PUNCT
fnp-3766	257	1	scale	scale	NOUN
fnp-3766	257	2	bar	bar	NOUN
fnp-3766	257	3	:	:	PUNCT
fnp-3766	257	4	150	150	NUM
fnp-3766	257	5	μm	μm	NOUN
fnp-3766	257	6	.	.	PUNCT
fnp-3766	258	1	prp.appsi/m20	prp.appsi/m20	NUM
fnp-3766	258	2	and	and	CCONJ
fnp-3766	258	3	prp.appsi	prp.appsi	NUM
fnp-3766	258	4	mice	mouse	NOUN
fnp-3766	258	5	injected	inject	VERB
fnp-3766	258	6	with	with	ADP
fnp-3766	258	7	ad	ad	NOUN
fnp-3766	258	8	brains	brain	NOUN
fnp-3766	258	9	developed	develop	VERB
fnp-3766	258	10	widespread	widespread	ADJ
fnp-3766	258	11	,	,	PUNCT
fnp-3766	258	12	robust	robust	ADJ
fnp-3766	258	13	aβ	aβ	NOUN
fnp-3766	258	14	pathology	pathology	NOUN
fnp-3766	258	15	by	by	ADP
fnp-3766	258	16	12	12	NUM
fnp-3766	258	17	months	month	NOUN
fnp-3766	258	18	post	post	ADJ
fnp-3766	258	19	-	-	NOUN
fnp-3766	258	20	injection	injection	ADJ
fnp-3766	258	21	(	(	PUNCT
fnp-3766	258	22	fig	fig	NOUN
fnp-3766	258	23	.	.	PUNCT
fnp-3766	259	1	4a	4a	NOUN
fnp-3766	259	2	and	and	CCONJ
fnp-3766	259	3	b	b	NOUN
fnp-3766	259	4	)	)	PUNCT
fnp-3766	259	5	.	.	PUNCT
fnp-3766	260	1	aβ	aβ	PRON
fnp-3766	260	2	deposition	deposition	NOUN
fnp-3766	260	3	was	be	AUX
fnp-3766	260	4	primarily	primarily	ADV
fnp-3766	260	5	diffuse	diffuse	ADJ
fnp-3766	260	6	and	and	CCONJ
fnp-3766	260	7	thio	thio	NOUN
fnp-3766	260	8	-	-	PUNCT
fnp-3766	260	9	s	s	X
fnp-3766	260	10	negative	negative	ADJ
fnp-3766	260	11	(	(	PUNCT
fnp-3766	260	12	fig	fig	NOUN
fnp-3766	260	13	.	.	PUNCT
fnp-3766	261	1	s10	s10	PROPN
fnp-3766	261	2	)	)	PUNCT
fnp-3766	261	3	.	.	PUNCT
fnp-3766	262	1	there	there	PRON
fnp-3766	262	2	was	be	VERB
fnp-3766	262	3	no	no	DET
fnp-3766	262	4	difference	difference	NOUN
fnp-3766	262	5	in	in	ADP
fnp-3766	262	6	aβ	aβ	NOUN
fnp-3766	262	7	seeding	seeding	NOUN
fnp-3766	262	8	capacity	capacity	NOUN
fnp-3766	262	9	between	between	ADP
fnp-3766	262	10	prp.appsi/m20	prp.appsi/m20	NUM
fnp-3766	262	11	and	and	CCONJ
fnp-3766	262	12	prp.appsi	prp.appsi	NUM
fnp-3766	262	13	mice	mouse	NOUN
fnp-3766	262	14	.	.	PUNCT
fnp-3766	263	1	interestingly	interestingly	ADV
fnp-3766	263	2	,	,	PUNCT
fnp-3766	263	3	ad	ad	NOUN
fnp-3766	263	4	/	/	SYM
fnp-3766	263	5	lbd	lbd	PROPN
fnp-3766	263	6	1	1	NUM
fnp-3766	263	7	and	and	CCONJ
fnp-3766	263	8	2	2	NUM
fnp-3766	263	9	also	also	ADV
fnp-3766	263	10	promoted	promote	VERB
fnp-3766	263	11	deposition	deposition	NOUN
fnp-3766	263	12	of	of	ADP
fnp-3766	263	13	aβ	aβ	PRON
fnp-3766	263	14	in	in	ADP
fnp-3766	263	15	mice	mouse	NOUN
fnp-3766	263	16	expressing	express	VERB
fnp-3766	263	17	appsi	appsi	PROPN
fnp-3766	263	18	with	with	ADP
fnp-3766	263	19	and	and	CCONJ
fnp-3766	263	20	without	without	ADP
fnp-3766	263	21	αsyn	αsyn	PROPN
fnp-3766	263	22	(	(	PUNCT
fnp-3766	263	23	fig	fig	NOUN
fnp-3766	263	24	.	.	PUNCT
fnp-3766	264	1	4	4	NUM
fnp-3766	264	2	)	)	PUNCT
fnp-3766	264	3	,	,	PUNCT
fnp-3766	264	4	indicating	indicate	VERB
fnp-3766	264	5	that	that	SCONJ
fnp-3766	264	6	the	the	DET
fnp-3766	264	7	ad	ad	NOUN
fnp-3766	264	8	/	/	SYM
fnp-3766	264	9	lbd	lbd	PROPN
fnp-3766	264	10	brains	brain	NOUN
fnp-3766	264	11	contained	contain	VERB
fnp-3766	264	12	considerable	considerable	ADJ
fnp-3766	264	13	levels	level	NOUN
fnp-3766	264	14	of	of	ADP
fnp-3766	264	15	aβ	aβ	NOUN
fnp-3766	264	16	seeds	seed	NOUN
fnp-3766	264	17	despite	despite	SCONJ
fnp-3766	264	18	a	a	DET
fnp-3766	264	19	much	much	ADV
fnp-3766	264	20	lower	low	ADJ
fnp-3766	264	21	burden	burden	NOUN
fnp-3766	264	22	of	of	ADP
fnp-3766	264	23	aβ	aβ	DET
fnp-3766	264	24	pathology	pathology	NOUN
fnp-3766	264	25	(	(	PUNCT
fnp-3766	264	26	fig	fig	NOUN
fnp-3766	264	27	.	.	PUNCT
fnp-3766	265	1	3	3	NUM
fnp-3766	265	2	)	)	PUNCT
fnp-3766	265	3	.	.	PUNCT
fnp-3766	266	1	none	none	NOUN
fnp-3766	266	2	of	of	ADP
fnp-3766	266	3	the	the	DET
fnp-3766	266	4	injected	inject	VERB
fnp-3766	266	5	animals	animal	NOUN
fnp-3766	266	6	developed	develop	VERB
fnp-3766	266	7	appreciable	appreciable	ADJ
fnp-3766	266	8	αsyn	αsyn	ADJ
fnp-3766	266	9	pathology	pathology	NOUN
fnp-3766	266	10	(	(	PUNCT
fnp-3766	266	11	data	datum	NOUN
fnp-3766	266	12	not	not	PART
fnp-3766	266	13	shown	show	VERB
fnp-3766	266	14	)	)	PUNCT
fnp-3766	266	15	.	.	PUNCT
fnp-3766	267	1	although	although	SCONJ
fnp-3766	267	2	two	two	NUM
fnp-3766	267	3	of	of	ADP
fnp-3766	267	4	the	the	DET
fnp-3766	267	5	donor	donor	NOUN
fnp-3766	267	6	cases	case	NOUN
fnp-3766	267	7	contained	contain	VERB
fnp-3766	267	8	significant	significant	ADJ
fnp-3766	267	9	caa	caa	NOUN
fnp-3766	267	10	pathology	pathology	PROPN
fnp-3766	267	11	,	,	PUNCT
fnp-3766	267	12	caa	caa	PROPN
fnp-3766	267	13	was	be	AUX
fnp-3766	267	14	not	not	PART
fnp-3766	267	15	seeded	seed	VERB
fnp-3766	267	16	in	in	ADP
fnp-3766	267	17	the	the	DET
fnp-3766	267	18	recipient	recipient	NOUN
fnp-3766	267	19	mice	mice	NOUN
fnp-3766	267	20	(	(	PUNCT
fnp-3766	267	21	fig	fig	NOUN
fnp-3766	267	22	.	.	PUNCT
fnp-3766	268	1	s10	s10	PROPN
fnp-3766	268	2	)	)	PUNCT
fnp-3766	268	3	.	.	PUNCT
fnp-3766	269	1	fig	fig	NOUN
fnp-3766	269	2	.	.	PUNCT
fnp-3766	270	1	4	4	NUM
fnp-3766	270	2	cerebral	cerebral	ADJ
fnp-3766	270	3	injection	injection	NOUN
fnp-3766	270	4	of	of	ADP
fnp-3766	270	5	ad	ad	NOUN
fnp-3766	270	6	and	and	CCONJ
fnp-3766	270	7	ad	ad	NOUN
fnp-3766	270	8	/	/	SYM
fnp-3766	270	9	lbd	lbd	PROPN
fnp-3766	270	10	brain	brain	NOUN
fnp-3766	270	11	lysates	lysate	NOUN
fnp-3766	270	12	results	result	VERB
fnp-3766	270	13	in	in	ADP
fnp-3766	270	14	widespread	widespread	ADJ
fnp-3766	270	15	amyloid	amyloid	NOUN
fnp-3766	270	16	deposition	deposition	NOUN
fnp-3766	270	17	and	and	CCONJ
fnp-3766	270	18	caa	caa	NOUN
fnp-3766	270	19	.	.	PUNCT
fnp-3766	271	1	overall	overall	ADJ
fnp-3766	271	2	schematic	schematic	ADJ
fnp-3766	271	3	of	of	ADP
fnp-3766	271	4	the	the	DET
fnp-3766	271	5	experiment	experiment	NOUN
fnp-3766	271	6	(	(	PUNCT
fnp-3766	271	7	a	a	NOUN
fnp-3766	271	8	)	)	PUNCT
fnp-3766	271	9	.	.	PUNCT
fnp-3766	272	1	newborn	newborn	ADJ
fnp-3766	272	2	p0	p0	NOUN
fnp-3766	272	3	mice	mouse	NOUN
fnp-3766	272	4	were	be	AUX
fnp-3766	272	5	injected	inject	VERB
fnp-3766	272	6	with	with	ADP
fnp-3766	272	7	ad	ad	NOUN
fnp-3766	272	8	,	,	PUNCT
fnp-3766	272	9	ad	ad	NOUN
fnp-3766	272	10	/	/	SYM
fnp-3766	272	11	lbd	lbd	PROPN
fnp-3766	272	12	,	,	PUNCT
fnp-3766	272	13	and	and	CCONJ
fnp-3766	272	14	ndc	ndc	NOUN
fnp-3766	272	15	brain	brain	NOUN
fnp-3766	272	16	lysates	lysate	NOUN
fnp-3766	272	17	and	and	CCONJ
fnp-3766	272	18	aged	age	VERB
fnp-3766	272	19	12	12	NUM
fnp-3766	272	20	months	month	NOUN
fnp-3766	272	21	.	.	PUNCT
fnp-3766	273	1	representative	representative	ADJ
fnp-3766	273	2	brain	brain	NOUN
fnp-3766	273	3	sections	section	NOUN
fnp-3766	273	4	(	(	PUNCT
fnp-3766	273	5	hippocampus	hippocampus	NOUN
fnp-3766	273	6	,	,	PUNCT
fnp-3766	273	7	cortex	cortex	NOUN
fnp-3766	273	8	,	,	PUNCT
fnp-3766	273	9	and	and	CCONJ
fnp-3766	273	10	meninges	meninge	NOUN
fnp-3766	273	11	)	)	PUNCT
fnp-3766	273	12	of	of	ADP
fnp-3766	273	13	(	(	PUNCT
fnp-3766	273	14	b	b	NOUN
fnp-3766	273	15	)	)	PUNCT
fnp-3766	273	16	prp.appsi/line	prp.appsi/line	NOUN
fnp-3766	273	17	m20	m20	X
fnp-3766	273	18	and	and	CCONJ
fnp-3766	273	19	(	(	PUNCT
fnp-3766	273	20	c	c	NOUN
fnp-3766	273	21	)	)	PUNCT
fnp-3766	273	22	prp.appsi	prp.appsi	PART
fnp-3766	273	23	mice	mouse	NOUN
fnp-3766	273	24	stained	stain	VERB
fnp-3766	273	25	with	with	ADP
fnp-3766	273	26	biotinylated	biotinylate	VERB
fnp-3766	273	27	anti	anti	ADJ
fnp-3766	273	28	-	-	ADJ
fnp-3766	273	29	aβ	aβ	ADJ
fnp-3766	273	30	mab	mab	NOUN
fnp-3766	273	31	ab5	ab5	NOUN
fnp-3766	273	32	(	(	PUNCT
fnp-3766	273	33	anti	anti	ADJ
fnp-3766	273	34	-	-	ADJ
fnp-3766	273	35	aβ	aβ	ADJ
fnp-3766	273	36	1	1	NUM
fnp-3766	273	37	-	-	SYM
fnp-3766	273	38	16	16	NUM
fnp-3766	273	39	)	)	PUNCT
fnp-3766	273	40	and	and	CCONJ
fnp-3766	273	41	counterstained	counterstaine	VERB
fnp-3766	273	42	with	with	ADP
fnp-3766	273	43	hematoxylin	hematoxylin	PROPN
fnp-3766	273	44	.	.	PUNCT
fnp-3766	274	1	n=4	n=4	VERB
fnp-3766	274	2	-	-	PUNCT
fnp-3766	274	3	8	8	NUM
fnp-3766	274	4	.	.	PUNCT
fnp-3766	274	5	scale	scale	NOUN
fnp-3766	274	6	bar	bar	NOUN
fnp-3766	274	7	:	:	PUNCT
fnp-3766	274	8	hippocampus	hippocampus	NOUN
fnp-3766	274	9	:	:	PUNCT
fnp-3766	274	10	250	250	NUM
fnp-3766	274	11	μm	μm	NOUN
fnp-3766	274	12	,	,	PUNCT
fnp-3766	274	13	cortex	cortex	NOUN
fnp-3766	274	14	and	and	CCONJ
fnp-3766	274	15	meninges	meninge	NOUN
fnp-3766	274	16	:	:	PUNCT
fnp-3766	274	17	50	50	NUM
fnp-3766	274	18	μm	μm	NOUN
fnp-3766	274	19	.	.	PUNCT
fnp-3766	275	1	seeding	seed	VERB
fnp-3766	275	2	diffuse	diffuse	NOUN
fnp-3766	275	3	aβ	aβ	DET
fnp-3766	275	4	deposition	deposition	NOUN
fnp-3766	275	5	does	do	AUX
fnp-3766	275	6	not	not	PART
fnp-3766	275	7	impair	impair	VERB
fnp-3766	275	8	performance	performance	NOUN
fnp-3766	275	9	in	in	ADP
fnp-3766	275	10	a	a	DET
fnp-3766	275	11	fear	fear	NOUN
fnp-3766	275	12	-	-	PUNCT
fnp-3766	275	13	conditioning	condition	VERB
fnp-3766	275	14	cognitive	cognitive	ADJ
fnp-3766	275	15	task	task	NOUN
fnp-3766	275	16	to	to	PART
fnp-3766	275	17	assess	assess	VERB
fnp-3766	275	18	whether	whether	SCONJ
fnp-3766	275	19	the	the	DET
fnp-3766	275	20	diffuse	diffuse	NOUN
fnp-3766	275	21	aβ	aβ	DET
fnp-3766	275	22	pathology	pathology	NOUN
fnp-3766	275	23	seeded	seed	VERB
fnp-3766	275	24	by	by	ADP
fnp-3766	275	25	ad	ad	NOUN
fnp-3766	275	26	brain	brain	NOUN
fnp-3766	275	27	produces	produce	VERB
fnp-3766	275	28	cognitive	cognitive	ADJ
fnp-3766	275	29	deficits	deficit	NOUN
fnp-3766	275	30	,	,	PUNCT
fnp-3766	275	31	an	an	DET
fnp-3766	275	32	additional	additional	ADJ
fnp-3766	275	33	cohort	cohort	NOUN
fnp-3766	275	34	of	of	ADP
fnp-3766	275	35	prp.appsi	prp.appsi	PROPN
fnp-3766	275	36	mice	mouse	NOUN
fnp-3766	275	37	were	be	AUX
fnp-3766	275	38	seeded	seed	VERB
fnp-3766	275	39	with	with	ADP
fnp-3766	275	40	ad	ad	NOUN
fnp-3766	275	41	1	1	NUM
fnp-3766	275	42	and	and	CCONJ
fnp-3766	275	43	2	2	NUM
fnp-3766	275	44	,	,	PUNCT
fnp-3766	275	45	or	or	CCONJ
fnp-3766	275	46	ndc	ndc	PROPN
fnp-3766	275	47	1	1	NUM
fnp-3766	275	48	,	,	PUNCT
fnp-3766	275	49	and	and	CCONJ
fnp-3766	275	50	then	then	ADV
fnp-3766	275	51	were	be	AUX
fnp-3766	275	52	aged	age	VERB
fnp-3766	275	53	12	12	NUM
fnp-3766	275	54	months	month	NOUN
fnp-3766	275	55	before	before	ADP
fnp-3766	275	56	behavioral	behavioral	ADJ
fnp-3766	275	57	testing	testing	NOUN
fnp-3766	275	58	in	in	ADP
fnp-3766	275	59	a	a	DET
fnp-3766	275	60	fear	fear	NOUN
fnp-3766	275	61	-	-	PUNCT
fnp-3766	275	62	conditioning	conditioning	NOUN
fnp-3766	275	63	paradigm	paradigm	NOUN
fnp-3766	275	64	.	.	PUNCT
fnp-3766	276	1	control	control	NOUN
fnp-3766	276	2	groups	group	NOUN
fnp-3766	276	3	were	be	AUX
fnp-3766	276	4	mice	mouse	NOUN
fnp-3766	276	5	that	that	PRON
fnp-3766	276	6	were	be	AUX
fnp-3766	276	7	not	not	PART
fnp-3766	276	8	injected	inject	VERB
fnp-3766	276	9	with	with	ADP
fnp-3766	276	10	brain	brain	NOUN
fnp-3766	276	11	lysate	lysate	NOUN
fnp-3766	276	12	and	and	CCONJ
fnp-3766	276	13	nontransgenic	nontransgenic	ADJ
fnp-3766	276	14	littermate	littermate	ADJ
fnp-3766	276	15	mice	mouse	NOUN
fnp-3766	276	16	that	that	PRON
fnp-3766	276	17	were	be	AUX
fnp-3766	276	18	either	either	ADV
fnp-3766	276	19	injected	inject	VERB
fnp-3766	276	20	with	with	ADP
fnp-3766	276	21	the	the	DET
fnp-3766	276	22	same	same	ADJ
fnp-3766	276	23	lysates	lysate	NOUN
fnp-3766	276	24	or	or	CCONJ
fnp-3766	276	25	uninjected	uninjected	ADJ
fnp-3766	276	26	.	.	PUNCT
fnp-3766	277	1	the	the	DET
fnp-3766	277	2	performance	performance	NOUN
fnp-3766	277	3	of	of	ADP
fnp-3766	277	4	the	the	DET
fnp-3766	277	5	animals	animal	NOUN
fnp-3766	277	6	in	in	ADP
fnp-3766	277	7	the	the	DET
fnp-3766	277	8	contextual	contextual	ADJ
fnp-3766	277	9	fear	fear	NOUN
fnp-3766	277	10	memory	memory	NOUN
fnp-3766	277	11	test	test	NOUN
fnp-3766	277	12	was	be	AUX
fnp-3766	277	13	conducted	conduct	VERB
fnp-3766	277	14	twice	twice	ADV
fnp-3766	277	15	.	.	PUNCT
fnp-3766	278	1	in	in	ADP
fnp-3766	278	2	the	the	DET
fnp-3766	278	3	first	first	ADJ
fnp-3766	278	4	round	round	NOUN
fnp-3766	278	5	of	of	ADP
fnp-3766	278	6	testing	testing	NOUN
fnp-3766	278	7	,	,	PUNCT
fnp-3766	278	8	the	the	DET
fnp-3766	278	9	performance	performance	NOUN
fnp-3766	278	10	of	of	ADP
fnp-3766	278	11	the	the	DET
fnp-3766	278	12	seeded	seeded	ADJ
fnp-3766	278	13	mice	mouse	NOUN
fnp-3766	278	14	was	be	AUX
fnp-3766	278	15	not	not	PART
fnp-3766	278	16	statistically	statistically	ADV
fnp-3766	278	17	different	different	ADJ
fnp-3766	278	18	from	from	ADP
fnp-3766	278	19	that	that	PRON
fnp-3766	278	20	of	of	ADP
fnp-3766	278	21	the	the	DET
fnp-3766	278	22	control	control	NOUN
fnp-3766	278	23	uninjected	uninjected	ADJ
fnp-3766	278	24	mice	mouse	NOUN
fnp-3766	278	25	(	(	PUNCT
fnp-3766	278	26	fig	fig	NOUN
fnp-3766	278	27	.	.	PUNCT
fnp-3766	279	1	5a	5a	NUM
fnp-3766	279	2	)	)	PUNCT
fnp-3766	279	3	.	.	PUNCT
fnp-3766	280	1	overall	overall	ADJ
fnp-3766	280	2	,	,	PUNCT
fnp-3766	280	3	in	in	ADP
fnp-3766	280	4	this	this	DET
fnp-3766	280	5	first	first	ADJ
fnp-3766	280	6	round	round	NOUN
fnp-3766	280	7	of	of	ADP
fnp-3766	280	8	testing	testing	NOUN
fnp-3766	280	9	,	,	PUNCT
fnp-3766	280	10	the	the	DET
fnp-3766	280	11	percentage	percentage	NOUN
fnp-3766	280	12	of	of	ADP
fnp-3766	280	13	time	time	NOUN
fnp-3766	280	14	animals	animal	NOUN
fnp-3766	280	15	that	that	PRON
fnp-3766	280	16	exhibited	exhibit	VERB
fnp-3766	280	17	freezing	freeze	VERB
fnp-3766	280	18	behavior	behavior	NOUN
fnp-3766	280	19	was	be	AUX
fnp-3766	280	20	relatively	relatively	ADV
fnp-3766	280	21	low	low	ADJ
fnp-3766	280	22	.	.	PUNCT
fnp-3766	281	1	in	in	ADP
fnp-3766	281	2	the	the	DET
fnp-3766	281	3	second	second	ADJ
fnp-3766	281	4	round	round	NOUN
fnp-3766	281	5	of	of	ADP
fnp-3766	281	6	testing	testing	NOUN
fnp-3766	281	7	,	,	PUNCT
fnp-3766	281	8	we	we	PRON
fnp-3766	281	9	expected	expect	VERB
fnp-3766	281	10	to	to	PART
fnp-3766	281	11	reinforce	reinforce	VERB
fnp-3766	281	12	memory	memory	NOUN
fnp-3766	281	13	of	of	ADP
fnp-3766	281	14	the	the	DET
fnp-3766	281	15	adverse	adverse	ADJ
fnp-3766	281	16	cue	cue	NOUN
fnp-3766	281	17	(	(	PUNCT
fnp-3766	281	18	context	context	NOUN
fnp-3766	281	19	or	or	CCONJ
fnp-3766	281	20	tone	tone	NOUN
fnp-3766	281	21	)	)	PUNCT
fnp-3766	281	22	and	and	CCONJ
fnp-3766	281	23	we	we	PRON
fnp-3766	281	24	observed	observe	VERB
fnp-3766	281	25	that	that	SCONJ
fnp-3766	281	26	re	re	VERB
fnp-3766	281	27	-	-	VERB
fnp-3766	281	28	tested	test	VERB
fnp-3766	281	29	mice	mouse	NOUN
fnp-3766	281	30	showed	show	VERB
fnp-3766	281	31	increased	increase	VERB
fnp-3766	281	32	levels	level	NOUN
fnp-3766	281	33	of	of	ADP
fnp-3766	281	34	freezing	freeze	VERB
fnp-3766	281	35	behavior	behavior	NOUN
fnp-3766	281	36	(	(	PUNCT
fnp-3766	281	37	fig	fig	NOUN
fnp-3766	281	38	.	.	PUNCT
fnp-3766	282	1	5b	5b	NUM
fnp-3766	282	2	)	)	PUNCT
fnp-3766	283	1	;	;	PUNCT
fnp-3766	283	2	however	however	ADV
fnp-3766	283	3	,	,	PUNCT
fnp-3766	283	4	there	there	PRON
fnp-3766	283	5	was	be	VERB
fnp-3766	283	6	still	still	ADV
fnp-3766	283	7	no	no	DET
fnp-3766	283	8	statistically	statistically	ADV
fnp-3766	283	9	significant	significant	ADJ
fnp-3766	283	10	difference	difference	NOUN
fnp-3766	283	11	in	in	ADP
fnp-3766	283	12	the	the	DET
fnp-3766	283	13	performance	performance	NOUN
fnp-3766	283	14	of	of	ADP
fnp-3766	283	15	the	the	DET
fnp-3766	283	16	seeded	seeded	ADJ
fnp-3766	283	17	mice	mouse	NOUN
fnp-3766	283	18	relative	relative	ADJ
fnp-3766	283	19	to	to	ADP
fnp-3766	283	20	any	any	DET
fnp-3766	283	21	control	control	NOUN
fnp-3766	283	22	.	.	PUNCT
fnp-3766	284	1	these	these	DET
fnp-3766	284	2	findings	finding	NOUN
fnp-3766	284	3	indicate	indicate	VERB
fnp-3766	284	4	that	that	SCONJ
fnp-3766	284	5	the	the	DET
fnp-3766	284	6	diffuse	diffuse	NOUN
fnp-3766	284	7	aβ	aβ	DET
fnp-3766	284	8	pathology	pathology	NOUN
fnp-3766	284	9	seeded	seed	VERB
fnp-3766	284	10	by	by	ADP
fnp-3766	284	11	these	these	DET
fnp-3766	284	12	homogenates	homogenate	NOUN
fnp-3766	284	13	of	of	ADP
fnp-3766	284	14	human	human	ADJ
fnp-3766	284	15	ad	ad	NOUN
fnp-3766	284	16	brain	brain	NOUN
fnp-3766	284	17	does	do	AUX
fnp-3766	284	18	not	not	PART
fnp-3766	284	19	produce	produce	VERB
fnp-3766	284	20	a	a	DET
fnp-3766	284	21	meaningful	meaningful	ADJ
fnp-3766	284	22	impairment	impairment	NOUN
fnp-3766	284	23	in	in	ADP
fnp-3766	284	24	the	the	DET
fnp-3766	284	25	systems	system	NOUN
fnp-3766	284	26	involved	involve	VERB
fnp-3766	284	27	in	in	ADP
fnp-3766	284	28	fear	fear	NOUN
fnp-3766	284	29	-	-	PUNCT
fnp-3766	284	30	conditioning	conditioning	NOUN
fnp-3766	284	31	memory	memory	NOUN
fnp-3766	284	32	tasks	task	NOUN
fnp-3766	284	33	.	.	PUNCT
fnp-3766	285	1	fig	fig	NOUN
fnp-3766	285	2	.	.	PUNCT
fnp-3766	286	1	5	5	NUM
fnp-3766	286	2	diffuse	diffuse	VERB
fnp-3766	286	3	amyloid	amyloid	NOUN
fnp-3766	286	4	seeding	seeding	NOUN
fnp-3766	286	5	does	do	AUX
fnp-3766	286	6	not	not	PART
fnp-3766	286	7	cause	cause	VERB
fnp-3766	286	8	cognitive	cognitive	ADJ
fnp-3766	286	9	impairment	impairment	NOUN
fnp-3766	286	10	in	in	ADP
fnp-3766	286	11	fear	fear	NOUN
fnp-3766	286	12	-	-	PUNCT
fnp-3766	286	13	conditioning	conditioning	NOUN
fnp-3766	286	14	.	.	PUNCT
fnp-3766	287	1	prp.appsi	prp.appsi	PROPN
fnp-3766	287	2	mice	mouse	NOUN
fnp-3766	287	3	seeded	seed	VERB
fnp-3766	287	4	by	by	ADP
fnp-3766	287	5	ad	ad	NOUN
fnp-3766	287	6	and	and	CCONJ
fnp-3766	287	7	ndc	ndc	NOUN
fnp-3766	287	8	lysates	lysate	NOUN
fnp-3766	287	9	,	,	PUNCT
fnp-3766	287	10	were	be	AUX
fnp-3766	287	11	aged	age	VERB
fnp-3766	287	12	12	12	NUM
fnp-3766	287	13	months	month	NOUN
fnp-3766	287	14	and	and	CCONJ
fnp-3766	287	15	subjected	subject	VERB
fnp-3766	287	16	to	to	ADP
fnp-3766	287	17	contextual	contextual	ADJ
fnp-3766	287	18	fear	fear	NOUN
fnp-3766	287	19	conditioning	conditioning	NOUN
fnp-3766	287	20	.	.	PUNCT
fnp-3766	288	1	mean	mean	VERB
fnp-3766	288	2	percentage	percentage	NOUN
fnp-3766	288	3	freezing	freeze	VERB
fnp-3766	288	4	±	±	NOUN
fnp-3766	288	5	standard	standard	ADJ
fnp-3766	288	6	error	error	NOUN
fnp-3766	288	7	of	of	ADP
fnp-3766	288	8	the	the	DET
fnp-3766	288	9	mean	mean	NOUN
fnp-3766	288	10	exhibited	exhibit	VERB
fnp-3766	288	11	by	by	ADP
fnp-3766	288	12	prp.appsi	prp.appsi	PROPN
fnp-3766	288	13	and	and	CCONJ
fnp-3766	288	14	nontransgenic	nontransgenic	ADJ
fnp-3766	288	15	(	(	PUNCT
fnp-3766	288	16	ntg	ntg	PROPN
fnp-3766	288	17	)	)	PUNCT
fnp-3766	288	18	littermates	littermate	NOUN
fnp-3766	288	19	injected	inject	VERB
fnp-3766	288	20	with	with	ADP
fnp-3766	288	21	ad	ad	NOUN
fnp-3766	288	22	cases	case	NOUN
fnp-3766	288	23	1	1	NUM
fnp-3766	288	24	or	or	CCONJ
fnp-3766	288	25	2	2	NUM
fnp-3766	288	26	and	and	CCONJ
fnp-3766	288	27	ndc	ndc	NOUN
fnp-3766	288	28	case	case	NOUN
fnp-3766	288	29	7	7	NUM
fnp-3766	288	30	.	.	PUNCT
fnp-3766	288	31	uninjected	uninjected	ADJ
fnp-3766	288	32	mice	mouse	NOUN
fnp-3766	288	33	were	be	AUX
fnp-3766	288	34	the	the	DET
fnp-3766	288	35	control	control	NOUN
fnp-3766	288	36	group	group	NOUN
fnp-3766	288	37	.	.	PUNCT
fnp-3766	289	1	(	(	PUNCT
fnp-3766	289	2	a	a	X
fnp-3766	289	3	)	)	PUNCT
fnp-3766	289	4	context	context	NOUN
fnp-3766	289	5	and	and	CCONJ
fnp-3766	289	6	tone	tone	NOUN
fnp-3766	289	7	paradigm	paradigm	NOUN
fnp-3766	289	8	.	.	PUNCT
fnp-3766	290	1	(	(	PUNCT
fnp-3766	290	2	b	b	X
fnp-3766	290	3	)	)	PUNCT
fnp-3766	290	4	a	a	DET
fnp-3766	290	5	subset	subset	NOUN
fnp-3766	290	6	of	of	ADP
fnp-3766	290	7	mice	mouse	NOUN
fnp-3766	290	8	were	be	AUX
fnp-3766	290	9	re	re	VERB
fnp-3766	290	10	-	-	VERB
fnp-3766	290	11	tested	test	VERB
fnp-3766	290	12	the	the	DET
fnp-3766	290	13	following	following	ADJ
fnp-3766	290	14	week	week	NOUN
fnp-3766	290	15	,	,	PUNCT
fnp-3766	290	16	context	context	NOUN
fnp-3766	290	17	and	and	CCONJ
fnp-3766	290	18	tone	tone	NOUN
fnp-3766	290	19	test	test	NOUN
fnp-3766	290	20	.	.	PUNCT
fnp-3766	291	1	n	n	CCONJ
fnp-3766	291	2	=	=	SYM
fnp-3766	291	3	6	6	NUM
fnp-3766	291	4	-	-	SYM
fnp-3766	291	5	8	8	NUM
fnp-3766	291	6	/	/	SYM
fnp-3766	291	7	tg	tg	PROPN
fnp-3766	291	8	,	,	PUNCT
fnp-3766	291	9	n	n	NOUN
fnp-3766	291	10	=	=	SYM
fnp-3766	291	11	12	12	NUM
fnp-3766	291	12	-	-	SYM
fnp-3766	291	13	16	16	NUM
fnp-3766	291	14	/	/	SYM
fnp-3766	291	15	ntg	ntg	NOUN
fnp-3766	291	16	mice	mouse	NOUN
fnp-3766	291	17	per	per	ADP
fnp-3766	291	18	group	group	NOUN
fnp-3766	291	19	.	.	PUNCT
fnp-3766	292	1	assessment	assessment	NOUN
fnp-3766	292	2	of	of	ADP
fnp-3766	292	3	aβ	aβ	NOUN
fnp-3766	292	4	seeding	seed	VERB
fnp-3766	292	5	efficiency	efficiency	NOUN
fnp-3766	292	6	in	in	ADP
fnp-3766	292	7	appsi	appsi	PROPN
fnp-3766	292	8	mice	mouse	NOUN
fnp-3766	292	9	to	to	PART
fnp-3766	292	10	examine	examine	VERB
fnp-3766	292	11	the	the	DET
fnp-3766	292	12	relative	relative	ADJ
fnp-3766	292	13	seeding	seeding	NOUN
fnp-3766	292	14	efficiency	efficiency	NOUN
fnp-3766	292	15	of	of	ADP
fnp-3766	292	16	different	different	ADJ
fnp-3766	292	17	types	type	NOUN
fnp-3766	292	18	of	of	ADP
fnp-3766	292	19	aβ	aβ	DET
fnp-3766	292	20	pathology	pathology	NOUN
fnp-3766	292	21	in	in	ADP
fnp-3766	292	22	prp.appsi	prp.appsi	PROPN
fnp-3766	292	23	mice	mouse	NOUN
fnp-3766	292	24	,	,	PUNCT
fnp-3766	292	25	we	we	PRON
fnp-3766	292	26	used	use	VERB
fnp-3766	292	27	an	an	DET
fnp-3766	292	28	approach	approach	NOUN
fnp-3766	292	29	in	in	ADP
fnp-3766	292	30	which	which	PRON
fnp-3766	292	31	homogenates	homogenate	NOUN
fnp-3766	292	32	from	from	ADP
fnp-3766	292	33	the	the	DET
fnp-3766	292	34	brains	brain	NOUN
fnp-3766	292	35	of	of	ADP
fnp-3766	292	36	4	4	NUM
fnp-3766	292	37	different	different	ADJ
fnp-3766	292	38	lines	line	NOUN
fnp-3766	292	39	of	of	ADP
fnp-3766	292	40	aged	aged	ADJ
fnp-3766	292	41	app	app	NOUN
fnp-3766	292	42	and	and	CCONJ
fnp-3766	292	43	app	app	PROPN
fnp-3766	292	44	/	/	SYM
fnp-3766	292	45	ps1	ps1	NOUN
fnp-3766	292	46	mice	mouse	NOUN
fnp-3766	292	47	were	be	AUX
fnp-3766	292	48	used	use	VERB
fnp-3766	292	49	to	to	PART
fnp-3766	292	50	seed	seed	NOUN
fnp-3766	292	51	accelerated	accelerate	VERB
fnp-3766	292	52	aβ	aβ	PRON
fnp-3766	292	53	deposition	deposition	NOUN
fnp-3766	292	54	(	(	PUNCT
fnp-3766	292	55	described	describe	VERB
fnp-3766	292	56	in	in	ADP
fnp-3766	292	57	table	table	NOUN
fnp-3766	292	58	2	2	NUM
fnp-3766	292	59	)	)	PUNCT
fnp-3766	292	60	.	.	PUNCT
fnp-3766	293	1	at	at	ADP
fnp-3766	293	2	these	these	DET
fnp-3766	293	3	advanced	advanced	ADJ
fnp-3766	293	4	ages	age	NOUN
fnp-3766	293	5	,	,	PUNCT
fnp-3766	293	6	each	each	PRON
fnp-3766	293	7	of	of	ADP
fnp-3766	293	8	the	the	DET
fnp-3766	293	9	mice	mouse	NOUN
fnp-3766	293	10	used	use	VERB
fnp-3766	293	11	to	to	PART
fnp-3766	293	12	produce	produce	VERB
fnp-3766	293	13	inoculum	inoculum	NOUN
fnp-3766	293	14	had	have	VERB
fnp-3766	293	15	substantial	substantial	ADJ
fnp-3766	293	16	aβ	aβ	DET
fnp-3766	293	17	pathology	pathology	NOUN
fnp-3766	293	18	(	(	PUNCT
fnp-3766	293	19	fig	fig	NOUN
fnp-3766	293	20	.	.	PUNCT
fnp-3766	294	1	s11	s11	PROPN
fnp-3766	294	2	)	)	PUNCT
fnp-3766	294	3	.	.	PUNCT
fnp-3766	295	1	following	follow	VERB
fnp-3766	295	2	the	the	DET
fnp-3766	295	3	strategy	strategy	NOUN
fnp-3766	295	4	used	use	VERB
fnp-3766	295	5	above	above	ADV
fnp-3766	295	6	,	,	PUNCT
fnp-3766	295	7	we	we	PRON
fnp-3766	295	8	injected	inject	VERB
fnp-3766	295	9	the	the	DET
fnp-3766	295	10	homogenates	homogenate	NOUN
fnp-3766	295	11	containing	contain	VERB
fnp-3766	295	12	aβ	aβ	ADP
fnp-3766	295	13	seeds	seed	NOUN
fnp-3766	295	14	into	into	ADP
fnp-3766	295	15	newborn	newborn	ADJ
fnp-3766	295	16	mice	mouse	NOUN
fnp-3766	295	17	on	on	ADP
fnp-3766	295	18	neonatal	neonatal	ADJ
fnp-3766	295	19	day	day	NOUN
fnp-3766	295	20	0	0	NUM
fnp-3766	295	21	,	,	PUNCT
fnp-3766	295	22	which	which	PRON
fnp-3766	295	23	were	be	AUX
fnp-3766	295	24	then	then	ADV
fnp-3766	295	25	aged	aged	ADJ
fnp-3766	295	26	to	to	ADP
fnp-3766	295	27	9	9	NUM
fnp-3766	295	28	,	,	PUNCT
fnp-3766	295	29	12	12	NUM
fnp-3766	295	30	,	,	PUNCT
fnp-3766	295	31	or	or	CCONJ
fnp-3766	295	32	15	15	NUM
fnp-3766	295	33	months	month	NOUN
fnp-3766	295	34	before	before	ADP
fnp-3766	295	35	euthanasia	euthanasia	NOUN
fnp-3766	295	36	and	and	CCONJ
fnp-3766	295	37	neuropathological	neuropathological	ADJ
fnp-3766	295	38	analysis	analysis	NOUN
fnp-3766	295	39	by	by	ADP
fnp-3766	295	40	campbell	campbell	PROPN
fnp-3766	295	41	switzer	switzer	PROPN
fnp-3766	295	42	silver	silver	NOUN
fnp-3766	295	43	stain	stain	NOUN
fnp-3766	295	44	and	and	CCONJ
fnp-3766	295	45	thio	thio	NOUN
fnp-3766	295	46	-	-	PUNCT
fnp-3766	295	47	s	s	NOUN
fnp-3766	295	48	staining	staining	NOUN
fnp-3766	295	49	.	.	PUNCT
fnp-3766	296	1	the	the	DET
fnp-3766	296	2	type	type	NOUN
fnp-3766	296	3	of	of	ADP
fnp-3766	296	4	pathology	pathology	NOUN
fnp-3766	296	5	noted	note	VERB
fnp-3766	296	6	and	and	CCONJ
fnp-3766	296	7	the	the	DET
fnp-3766	296	8	relative	relative	ADJ
fnp-3766	296	9	abundance	abundance	NOUN
fnp-3766	296	10	score	score	NOUN
fnp-3766	296	11	are	be	AUX
fnp-3766	296	12	noted	note	VERB
fnp-3766	296	13	at	at	ADP
fnp-3766	296	14	the	the	DET
fnp-3766	296	15	bottom	bottom	NOUN
fnp-3766	296	16	of	of	ADP
fnp-3766	296	17	each	each	DET
fnp-3766	296	18	column	column	NOUN
fnp-3766	296	19	of	of	ADP
fnp-3766	296	20	images	image	NOUN
fnp-3766	296	21	in	in	ADP
fnp-3766	296	22	figure	figure	NOUN
fnp-3766	296	23	6	6	NUM
fnp-3766	296	24	.	.	PUNCT
fnp-3766	297	1	in	in	ADP
fnp-3766	297	2	all	all	PRON
fnp-3766	297	3	of	of	ADP
fnp-3766	297	4	the	the	DET
fnp-3766	297	5	prp.appsi	prp.appsi	NUM
fnp-3766	297	6	mice	mouse	NOUN
fnp-3766	297	7	injected	inject	VERB
fnp-3766	297	8	with	with	ADP
fnp-3766	297	9	brain	brain	NOUN
fnp-3766	297	10	homogenate	homogenate	NOUN
fnp-3766	297	11	seeds	seed	NOUN
fnp-3766	297	12	from	from	ADP
fnp-3766	297	13	mice	mouse	NOUN
fnp-3766	297	14	that	that	PRON
fnp-3766	297	15	primarily	primarily	ADV
fnp-3766	297	16	exhibited	exhibit	VERB
fnp-3766	297	17	cored	core	VERB
fnp-3766	297	18	plaques	plaque	NOUN
fnp-3766	297	19	,	,	PUNCT
fnp-3766	297	20	we	we	PRON
fnp-3766	297	21	observed	observe	VERB
fnp-3766	297	22	an	an	DET
fnp-3766	297	23	obvious	obvious	ADJ
fnp-3766	297	24	shift	shift	NOUN
fnp-3766	297	25	in	in	ADP
fnp-3766	297	26	the	the	DET
fnp-3766	297	27	type	type	NOUN
fnp-3766	297	28	of	of	ADP
fnp-3766	297	29	aβ	aβ	DET
fnp-3766	297	30	deposits	deposit	NOUN
fnp-3766	297	31	in	in	ADP
fnp-3766	297	32	recipient	recipient	NOUN
fnp-3766	297	33	mice	mouse	NOUN
fnp-3766	297	34	to	to	PART
fnp-3766	297	35	match	match	VERB
fnp-3766	297	36	the	the	DET
fnp-3766	297	37	pathology	pathology	NOUN
fnp-3766	297	38	found	find	VERB
fnp-3766	297	39	in	in	ADP
fnp-3766	297	40	the	the	DET
fnp-3766	297	41	donor	donor	NOUN
fnp-3766	297	42	mice	mouse	NOUN
fnp-3766	297	43	used	use	VERB
fnp-3766	297	44	for	for	ADP
fnp-3766	297	45	seeding	seeding	NOUN
fnp-3766	297	46	(	(	PUNCT
fnp-3766	297	47	fig	fig	NOUN
fnp-3766	297	48	.	.	PUNCT
fnp-3766	298	1	6	6	NUM
fnp-3766	298	2	)	)	PUNCT
fnp-3766	298	3	.	.	PUNCT
fnp-3766	299	1	self	self	NOUN
fnp-3766	299	2	-	-	PUNCT
fnp-3766	299	3	seeding	seeding	NOUN
fnp-3766	299	4	of	of	ADP
fnp-3766	299	5	newborn	newborn	ADJ
fnp-3766	299	6	prp.appsi	prp.appsi	NOUN
fnp-3766	299	7	mice	mouse	NOUN
fnp-3766	299	8	with	with	ADP
fnp-3766	299	9	brain	brain	NOUN
fnp-3766	299	10	homogenates	homogenate	NOUN
fnp-3766	299	11	from	from	ADP
fnp-3766	299	12	aged	aged	ADJ
fnp-3766	299	13	prp.appsi	prp.appsi	NUM
fnp-3766	299	14	mice	mouse	NOUN
fnp-3766	299	15	produced	produce	VERB
fnp-3766	299	16	diffuse	diffuse	NOUN
fnp-3766	299	17	deposits	deposit	NOUN
fnp-3766	299	18	(	(	PUNCT
fnp-3766	299	19	fig	fig	NOUN
fnp-3766	299	20	.	.	PUNCT
fnp-3766	300	1	6	6	NUM
fnp-3766	300	2	)	)	PUNCT
fnp-3766	300	3	,	,	PUNCT
fnp-3766	300	4	which	which	PRON
fnp-3766	300	5	was	be	AUX
fnp-3766	300	6	the	the	DET
fnp-3766	300	7	predominant	predominant	ADJ
fnp-3766	300	8	form	form	NOUN
fnp-3766	300	9	of	of	ADP
fnp-3766	300	10	aβ	aβ	DET
fnp-3766	300	11	pathology	pathology	NOUN
fnp-3766	300	12	in	in	ADP
fnp-3766	300	13	the	the	DET
fnp-3766	300	14	prp.appsi	prp.appsi	NUM
fnp-3766	300	15	animal	animal	NOUN
fnp-3766	300	16	used	use	VERB
fnp-3766	300	17	to	to	PART
fnp-3766	300	18	generate	generate	VERB
fnp-3766	300	19	the	the	DET
fnp-3766	300	20	seeding	seeding	NOUN
fnp-3766	300	21	homogenate	homogenate	NOUN
fnp-3766	300	22	(	(	PUNCT
fnp-3766	300	23	fig	fig	NOUN
fnp-3766	300	24	.	.	PUNCT
fnp-3766	301	1	s11	s11	PROPN
fnp-3766	301	2	)	)	PUNCT
fnp-3766	301	3	.	.	PUNCT
fnp-3766	302	1	similarly	similarly	ADV
fnp-3766	302	2	,	,	PUNCT
fnp-3766	302	3	the	the	DET
fnp-3766	302	4	predominant	predominant	ADJ
fnp-3766	302	5	pathology	pathology	NOUN
fnp-3766	302	6	in	in	ADP
fnp-3766	302	7	the	the	DET
fnp-3766	302	8	~25	~25	ADJ
fnp-3766	302	9	month	month	NOUN
fnp-3766	302	10	old	old	ADJ
fnp-3766	302	11	tet.moaβ	tet.moaβ	PRON
fnp-3766	302	12	animal	animal	NOUN
fnp-3766	302	13	used	use	VERB
fnp-3766	302	14	to	to	PART
fnp-3766	302	15	prepare	prepare	VERB
fnp-3766	302	16	seeding	seeding	NOUN
fnp-3766	302	17	homogenate	homogenate	NOUN
fnp-3766	302	18	was	be	AUX
fnp-3766	302	19	diffuse	diffuse	ADJ
fnp-3766	302	20	aβ	aβ	ADP
fnp-3766	302	21	deposits	deposit	NOUN
fnp-3766	302	22	(	(	PUNCT
fnp-3766	302	23	fig	fig	NOUN
fnp-3766	302	24	.	.	PUNCT
fnp-3766	302	25	s11)(48	s11)(48	PROPN
fnp-3766	302	26	)	)	PUNCT
fnp-3766	302	27	,	,	PUNCT
fnp-3766	302	28	and	and	CCONJ
fnp-3766	302	29	brain	brain	NOUN
fnp-3766	302	30	homogenates	homogenate	NOUN
fnp-3766	302	31	from	from	ADP
fnp-3766	302	32	this	this	DET
fnp-3766	302	33	animal	animal	NOUN
fnp-3766	302	34	efficiently	efficiently	ADV
fnp-3766	302	35	seeded	seed	VERB
fnp-3766	302	36	the	the	DET
fnp-3766	302	37	deposition	deposition	NOUN
fnp-3766	302	38	of	of	ADP
fnp-3766	302	39	human	human	ADJ
fnp-3766	302	40	aβ	aβ	NOUN
fnp-3766	302	41	in	in	ADP
fnp-3766	302	42	the	the	DET
fnp-3766	302	43	prp.appsi	prp.appsi	NUM
fnp-3766	302	44	mice	mouse	NOUN
fnp-3766	302	45	to	to	PART
fnp-3766	302	46	produce	produce	VERB
fnp-3766	302	47	diffuse	diffuse	NOUN
fnp-3766	302	48	deposits	deposit	NOUN
fnp-3766	302	49	(	(	PUNCT
fnp-3766	302	50	fig	fig	NOUN
fnp-3766	302	51	.	.	PUNCT
fnp-3766	303	1	6	6	NUM
fnp-3766	303	2	)	)	PUNCT
fnp-3766	303	3	.	.	PUNCT
fnp-3766	304	1	prp.appsi	prp.appsi	PROPN
fnp-3766	304	2	mice	mouse	NOUN
fnp-3766	304	3	seeded	seed	VERB
fnp-3766	304	4	with	with	ADP
fnp-3766	304	5	homogenates	homogenate	NOUN
fnp-3766	304	6	from	from	ADP
fnp-3766	304	7	donors	donor	NOUN
fnp-3766	304	8	that	that	PRON
fnp-3766	304	9	had	have	AUX
fnp-3766	304	10	primarily	primarily	ADV
fnp-3766	304	11	cored	core	VERB
fnp-3766	304	12	deposits	deposit	NOUN
fnp-3766	304	13	had	have	VERB
fnp-3766	304	14	lower	low	ADJ
fnp-3766	304	15	aβ	aβ	ADP
fnp-3766	304	16	burden	burden	NOUN
fnp-3766	304	17	scores	score	NOUN
fnp-3766	304	18	,	,	PUNCT
fnp-3766	304	19	but	but	CCONJ
fnp-3766	304	20	importantly	importantly	ADV
fnp-3766	304	21	we	we	PRON
fnp-3766	304	22	observed	observe	VERB
fnp-3766	304	23	a	a	DET
fnp-3766	304	24	shift	shift	NOUN
fnp-3766	304	25	in	in	ADP
fnp-3766	304	26	the	the	DET
fnp-3766	304	27	neuropathologic	neuropathologic	ADJ
fnp-3766	304	28	features	feature	NOUN
fnp-3766	304	29	of	of	ADP
fnp-3766	304	30	the	the	DET
fnp-3766	304	31	recipient	recipient	NOUN
fnp-3766	304	32	mice	mouse	NOUN
fnp-3766	304	33	to	to	ADP
fnp-3766	304	34	a	a	DET
fnp-3766	304	35	much	much	ADV
fnp-3766	304	36	higher	high	ADJ
fnp-3766	304	37	incidence	incidence	NOUN
fnp-3766	304	38	of	of	ADP
fnp-3766	304	39	cored	core	VERB
fnp-3766	304	40	deposits	deposit	NOUN
fnp-3766	304	41	(	(	PUNCT
fnp-3766	304	42	fig	fig	NOUN
fnp-3766	304	43	.	.	PUNCT
fnp-3766	304	44	6	6	NUM
fnp-3766	304	45	)	)	PUNCT
fnp-3766	304	46	.	.	PUNCT
fnp-3766	305	1	interestingly	interestingly	ADV
fnp-3766	305	2	,	,	PUNCT
fnp-3766	305	3	the	the	DET
fnp-3766	305	4	morphology	morphology	NOUN
fnp-3766	305	5	of	of	ADP
fnp-3766	305	6	deposits	deposit	NOUN
fnp-3766	305	7	in	in	ADP
fnp-3766	305	8	the	the	DET
fnp-3766	305	9	seeded	seeded	ADJ
fnp-3766	305	10	prp.appsi	prp.appsi	NUM
fnp-3766	305	11	mice	mouse	NOUN
fnp-3766	305	12	was	be	AUX
fnp-3766	305	13	not	not	PART
fnp-3766	305	14	quite	quite	ADV
fnp-3766	305	15	identical	identical	ADJ
fnp-3766	305	16	to	to	ADP
fnp-3766	305	17	the	the	DET
fnp-3766	305	18	source	source	NOUN
fnp-3766	305	19	prp.huaβ/ps1	prp.huaβ/ps1	NOUN
fnp-3766	305	20	mice	mouse	NOUN
fnp-3766	305	21	in	in	SCONJ
fnp-3766	305	22	that	that	SCONJ
fnp-3766	305	23	the	the	DET
fnp-3766	305	24	seeded	seeded	ADJ
fnp-3766	305	25	deposits	deposit	NOUN
fnp-3766	305	26	were	be	AUX
fnp-3766	305	27	smaller	small	ADJ
fnp-3766	305	28	and	and	CCONJ
fnp-3766	305	29	appeared	appear	VERB
fnp-3766	305	30	to	to	PART
fnp-3766	305	31	be	be	AUX
fnp-3766	305	32	more	more	ADV
fnp-3766	305	33	compact	compact	ADJ
fnp-3766	305	34	than	than	ADP
fnp-3766	305	35	the	the	DET
fnp-3766	305	36	donor	donor	NOUN
fnp-3766	305	37	line	line	NOUN
fnp-3766	305	38	.	.	PUNCT
fnp-3766	306	1	these	these	DET
fnp-3766	306	2	small	small	ADJ
fnp-3766	306	3	dense	dense	ADJ
fnp-3766	306	4	deposits	deposit	NOUN
fnp-3766	306	5	were	be	AUX
fnp-3766	306	6	thio	thio	NOUN
fnp-3766	306	7	-	-	PUNCT
fnp-3766	306	8	s	s	NOUN
fnp-3766	306	9	positive	positive	ADJ
fnp-3766	306	10	(	(	PUNCT
fnp-3766	306	11	fig	fig	NOUN
fnp-3766	306	12	.	.	PUNCT
fnp-3766	307	1	6	6	NUM
fnp-3766	307	2	)	)	PUNCT
fnp-3766	307	3	.	.	PUNCT
fnp-3766	308	1	similar	similar	ADJ
fnp-3766	308	2	small	small	ADJ
fnp-3766	308	3	dense	dense	ADJ
fnp-3766	308	4	core	core	NOUN
fnp-3766	308	5	deposits	deposit	NOUN
fnp-3766	308	6	that	that	PRON
fnp-3766	308	7	were	be	AUX
fnp-3766	308	8	thio	thio	NOUN
fnp-3766	308	9	-	-	PUNCT
fnp-3766	308	10	s	s	NOUN
fnp-3766	308	11	positive	positive	ADJ
fnp-3766	308	12	were	be	AUX
fnp-3766	308	13	observed	observe	VERB
fnp-3766	308	14	in	in	ADP
fnp-3766	308	15	the	the	DET
fnp-3766	308	16	cortex	cortex	NOUN
fnp-3766	308	17	of	of	ADP
fnp-3766	308	18	prp.appsi	prp.appsi	PROPN
fnp-3766	308	19	mice	mouse	NOUN
fnp-3766	308	20	injected	inject	VERB
fnp-3766	308	21	with	with	ADP
fnp-3766	308	22	brain	brain	NOUN
fnp-3766	308	23	homogenates	homogenate	NOUN
fnp-3766	308	24	from	from	ADP
fnp-3766	308	25	the	the	DET
fnp-3766	308	26	prp.moaβ/ps1	prp.moaβ/ps1	NOUN
fnp-3766	308	27	mice	mice	NOUN
fnp-3766	308	28	(	(	PUNCT
fnp-3766	308	29	fig	fig	NOUN
fnp-3766	308	30	.	.	PUNCT
fnp-3766	309	1	6	6	NUM
fnp-3766	309	2	)	)	PUNCT
fnp-3766	309	3	.	.	PUNCT
fnp-3766	310	1	collectively	collectively	ADV
fnp-3766	310	2	,	,	PUNCT
fnp-3766	310	3	these	these	DET
fnp-3766	310	4	findings	finding	NOUN
fnp-3766	310	5	demonstrate	demonstrate	VERB
fnp-3766	310	6	the	the	DET
fnp-3766	310	7	relative	relative	ADJ
fnp-3766	310	8	ease	ease	NOUN
fnp-3766	310	9	with	with	ADP
fnp-3766	310	10	which	which	PRON
fnp-3766	310	11	diffuse	diffuse	NOUN
fnp-3766	310	12	aβ	aβ	DET
fnp-3766	310	13	pathology	pathology	NOUN
fnp-3766	310	14	can	can	AUX
fnp-3766	310	15	be	be	AUX
fnp-3766	310	16	induced	induce	VERB
fnp-3766	310	17	in	in	ADP
fnp-3766	310	18	prp.appsi	prp.appsi	NUM
fnp-3766	310	19	mice	mouse	NOUN
fnp-3766	310	20	.	.	PUNCT
fnp-3766	311	1	fig	fig	NOUN
fnp-3766	311	2	.	.	PUNCT
fnp-3766	312	1	6	6	NUM
fnp-3766	312	2	comparison	comparison	NOUN
fnp-3766	312	3	of	of	ADP
fnp-3766	312	4	seeding	seed	VERB
fnp-3766	312	5	activity	activity	NOUN
fnp-3766	312	6	between	between	ADP
fnp-3766	312	7	transgenic	transgenic	NOUN
fnp-3766	312	8	mice	mouse	NOUN
fnp-3766	312	9	that	that	PRON
fnp-3766	312	10	exhibit	exhibit	VERB
fnp-3766	312	11	diffuse	diffuse	NOUN
fnp-3766	312	12	versus	versus	ADP
fnp-3766	312	13	cored	core	VERB
fnp-3766	312	14	aβ	aβ	PRON
fnp-3766	312	15	pathology	pathology	NOUN
fnp-3766	312	16	.	.	PUNCT
fnp-3766	313	1	we	we	PRON
fnp-3766	313	2	selected	select	VERB
fnp-3766	313	3	brains	brain	NOUN
fnp-3766	313	4	from	from	ADP
fnp-3766	313	5	four	four	NUM
fnp-3766	313	6	sources	source	NOUN
fnp-3766	313	7	that	that	PRON
fnp-3766	313	8	exhibit	exhibit	VERB
fnp-3766	313	9	either	either	CCONJ
fnp-3766	313	10	diffuse	diffuse	NOUN
fnp-3766	313	11	or	or	CCONJ
fnp-3766	313	12	cored	core	VERB
fnp-3766	313	13	neuritic	neuritic	ADJ
fnp-3766	313	14	aβ	aβ	NOUN
fnp-3766	313	15	deposits	deposit	NOUN
fnp-3766	313	16	(	(	PUNCT
fnp-3766	313	17	see	see	VERB
fnp-3766	313	18	fig	fig	NOUN
fnp-3766	313	19	.	.	PUNCT
fnp-3766	314	1	s11	s11	PROPN
fnp-3766	314	2	)	)	PUNCT
fnp-3766	314	3	.	.	PUNCT
fnp-3766	315	1	newborn	newborn	ADJ
fnp-3766	315	2	prp.appsi	prp.appsi	PROPN
fnp-3766	315	3	mice	mouse	NOUN
fnp-3766	315	4	were	be	AUX
fnp-3766	315	5	injected	inject	VERB
fnp-3766	315	6	with	with	ADP
fnp-3766	315	7	homogenate	homogenate	NOUN
fnp-3766	315	8	from	from	ADP
fnp-3766	315	9	each	each	PRON
fnp-3766	315	10	of	of	ADP
fnp-3766	315	11	the	the	DET
fnp-3766	315	12	four	four	NUM
fnp-3766	315	13	sources	source	NOUN
fnp-3766	315	14	identified	identify	VERB
fnp-3766	315	15	at	at	ADP
fnp-3766	315	16	the	the	DET
fnp-3766	315	17	top	top	NOUN
fnp-3766	315	18	of	of	ADP
fnp-3766	315	19	the	the	DET
fnp-3766	315	20	figure	figure	NOUN
fnp-3766	315	21	.	.	PUNCT
fnp-3766	316	1	compared	compare	VERB
fnp-3766	316	2	to	to	ADP
fnp-3766	316	3	uninjected	uninjected	ADJ
fnp-3766	316	4	mice	mouse	NOUN
fnp-3766	316	5	,	,	PUNCT
fnp-3766	316	6	prp.appsi	prp.appsi	NUM
fnp-3766	316	7	mice	mouse	NOUN
fnp-3766	316	8	injected	inject	VERB
fnp-3766	316	9	with	with	ADP
fnp-3766	316	10	brain	brain	NOUN
fnp-3766	316	11	homogenates	homogenate	NOUN
fnp-3766	316	12	from	from	ADP
fnp-3766	316	13	any	any	DET
fnp-3766	316	14	source	source	NOUN
fnp-3766	316	15	showed	show	VERB
fnp-3766	316	16	an	an	DET
fnp-3766	316	17	induction	induction	NOUN
fnp-3766	316	18	of	of	ADP
fnp-3766	316	19	aβ	aβ	DET
fnp-3766	316	20	pathology	pathology	NOUN
fnp-3766	316	21	.	.	PUNCT
fnp-3766	317	1	inoculum	inoculum	NOUN
fnp-3766	317	2	from	from	ADP
fnp-3766	317	3	aged	aged	ADJ
fnp-3766	317	4	prp.appsi	prp.appsi	NOUN
fnp-3766	317	5	and	and	CCONJ
fnp-3766	317	6	tet.moaβ	tet.moaβ	VERB
fnp-3766	317	7	mice	mouse	NOUN
fnp-3766	317	8	,	,	PUNCT
fnp-3766	317	9	which	which	PRON
fnp-3766	317	10	primarily	primarily	ADV
fnp-3766	317	11	exhibit	exhibit	VERB
fnp-3766	317	12	diffuse	diffuse	NOUN
fnp-3766	317	13	aβ	aβ	DET
fnp-3766	317	14	pathology	pathology	NOUN
fnp-3766	317	15	(	(	PUNCT
fnp-3766	317	16	37	37	NUM
fnp-3766	317	17	,	,	PUNCT
fnp-3766	317	18	48	48	NUM
fnp-3766	317	19	)	)	PUNCT
fnp-3766	317	20	,	,	PUNCT
fnp-3766	317	21	robustly	robustly	ADV
fnp-3766	317	22	seeded	seed	VERB
fnp-3766	317	23	diffuse	diffuse	NOUN
fnp-3766	317	24	pathology	pathology	NOUN
fnp-3766	317	25	in	in	ADP
fnp-3766	317	26	the	the	DET
fnp-3766	317	27	injected	inject	VERB
fnp-3766	317	28	prp.appsi	prp.appsi	NUM
fnp-3766	317	29	mice	mouse	NOUN
fnp-3766	317	30	(	(	PUNCT
fnp-3766	317	31	severity	severity	NOUN
fnp-3766	317	32	of	of	ADP
fnp-3766	317	33	pathology	pathology	NOUN
fnp-3766	317	34	and	and	CCONJ
fnp-3766	317	35	number	number	NOUN
fnp-3766	317	36	of	of	ADP
fnp-3766	317	37	animals	animal	NOUN
fnp-3766	317	38	indicated	indicate	VERB
fnp-3766	317	39	at	at	ADP
fnp-3766	317	40	the	the	DET
fnp-3766	317	41	bottom	bottom	NOUN
fnp-3766	317	42	of	of	ADP
fnp-3766	317	43	the	the	DET
fnp-3766	317	44	figure	figure	NOUN
fnp-3766	317	45	)	)	PUNCT
fnp-3766	317	46	.	.	PUNCT
fnp-3766	318	1	inoculum	inoculum	NOUN
fnp-3766	318	2	from	from	ADP
fnp-3766	318	3	aged	aged	ADJ
fnp-3766	318	4	prp.huaβ/ps1	prp.huaβ/ps1	NOUN
fnp-3766	318	5	(	(	PUNCT
fnp-3766	318	6	a.k.a	a.k.a	PROPN
fnp-3766	318	7	.	.	PROPN
fnp-3766	318	8	appswe	appswe	PROPN
fnp-3766	318	9	/	/	SYM
fnp-3766	318	10	ps1de9	ps1de9	NOUN
fnp-3766	318	11	)	)	PUNCT
fnp-3766	318	12	and	and	CCONJ
fnp-3766	318	13	prp.moaβ/ps1	prp.moaβ/ps1	NOUN
fnp-3766	318	14	mice	mouse	NOUN
fnp-3766	318	15	,	,	PUNCT
fnp-3766	318	16	which	which	PRON
fnp-3766	318	17	primarily	primarily	ADV
fnp-3766	318	18	exhibit	exhibit	VERB
fnp-3766	318	19	cored	core	VERB
fnp-3766	318	20	neuritic	neuritic	ADJ
fnp-3766	318	21	deposits	deposit	NOUN
fnp-3766	318	22	(	(	PUNCT
fnp-3766	318	23	37	37	NUM
fnp-3766	318	24	,	,	PUNCT
fnp-3766	318	25	48	48	NUM
fnp-3766	318	26	)	)	PUNCT
fnp-3766	318	27	,	,	PUNCT
fnp-3766	318	28	induced	induce	VERB
fnp-3766	318	29	the	the	DET
fnp-3766	318	30	deposition	deposition	NOUN
fnp-3766	318	31	of	of	ADP
fnp-3766	318	32	a	a	DET
fnp-3766	318	33	limited	limited	ADJ
fnp-3766	318	34	number	number	NOUN
fnp-3766	318	35	of	of	ADP
fnp-3766	318	36	cored	core	VERB
fnp-3766	318	37	aβ	aβ	NUM
fnp-3766	318	38	deposits	deposit	NOUN
fnp-3766	318	39	in	in	ADP
fnp-3766	318	40	injected	inject	VERB
fnp-3766	318	41	prp.appsi	prp.appsi	NUM
fnp-3766	318	42	mice	mouse	NOUN
fnp-3766	318	43	with	with	ADP
fnp-3766	318	44	little	little	ADJ
fnp-3766	318	45	or	or	CCONJ
fnp-3766	318	46	no	no	PRON
fnp-3766	318	47	diffuse	diffuse	ADJ
fnp-3766	318	48	deposits	deposit	NOUN
fnp-3766	318	49	.	.	PUNCT
fnp-3766	319	1	d	d	NOUN
fnp-3766	319	2	=	=	PUNCT
fnp-3766	319	3	diffuse	diffuse	VERB
fnp-3766	319	4	aβ	aβ	PRON
fnp-3766	319	5	pathology	pathology	NOUN
fnp-3766	319	6	.	.	PUNCT
fnp-3766	320	1	m	m	VERB
fnp-3766	320	2	=	=	NOUN
fnp-3766	320	3	mixed	mixed	ADJ
fnp-3766	320	4	diffuse	diffuse	NOUN
fnp-3766	320	5	and	and	CCONJ
fnp-3766	320	6	cored	core	VERB
fnp-3766	320	7	deposits	deposit	NOUN
fnp-3766	320	8	.	.	PUNCT
fnp-3766	321	1	c	c	X
fnp-3766	321	2	=	=	PRON
fnp-3766	321	3	cored	core	VERB
fnp-3766	321	4	,	,	PUNCT
fnp-3766	321	5	neuritic	neuritic	ADJ
fnp-3766	321	6	deposits	deposit	NOUN
fnp-3766	321	7	.	.	PUNCT
fnp-3766	322	1	discussion	discussion	NOUN
fnp-3766	322	2	we	we	PRON
fnp-3766	322	3	investigated	investigate	VERB
fnp-3766	322	4	whether	whether	SCONJ
fnp-3766	322	5	injection	injection	NOUN
fnp-3766	322	6	of	of	ADP
fnp-3766	322	7	neonatal	neonatal	ADJ
fnp-3766	322	8	app	app	NOUN
fnp-3766	322	9	,	,	PUNCT
fnp-3766	322	10	app	app	PROPN
fnp-3766	322	11	/	/	SYM
fnp-3766	322	12	tau	tau	PROPN
fnp-3766	322	13	,	,	PUNCT
fnp-3766	322	14	or	or	CCONJ
fnp-3766	322	15	app	app	PRON
fnp-3766	322	16	/	/	SYM
fnp-3766	322	17	αsyn	αsyn	NOUN
fnp-3766	322	18	mice	mouse	NOUN
fnp-3766	322	19	with	with	ADP
fnp-3766	322	20	ad	ad	NOUN
fnp-3766	322	21	or	or	CCONJ
fnp-3766	322	22	ad	ad	NOUN
fnp-3766	322	23	/	/	SYM
fnp-3766	322	24	lbd	lbd	PROPN
fnp-3766	322	25	brain	brain	NOUN
fnp-3766	322	26	homogenates	homogenate	NOUN
fnp-3766	322	27	could	could	AUX
fnp-3766	322	28	be	be	AUX
fnp-3766	322	29	used	use	VERB
fnp-3766	322	30	as	as	ADP
fnp-3766	322	31	a	a	DET
fnp-3766	322	32	paradigm	paradigm	NOUN
fnp-3766	322	33	to	to	PART
fnp-3766	322	34	generate	generate	VERB
fnp-3766	322	35	mice	mouse	NOUN
fnp-3766	322	36	that	that	PRON
fnp-3766	322	37	model	model	VERB
fnp-3766	322	38	the	the	DET
fnp-3766	322	39	mixed	mixed	ADJ
fnp-3766	322	40	pathology	pathology	NOUN
fnp-3766	322	41	associated	associate	VERB
fnp-3766	322	42	with	with	ADP
fnp-3766	322	43	each	each	DET
fnp-3766	322	44	disease	disease	NOUN
fnp-3766	322	45	.	.	PUNCT
fnp-3766	323	1	despite	despite	SCONJ
fnp-3766	323	2	the	the	DET
fnp-3766	323	3	widespread	widespread	ADJ
fnp-3766	323	4	induction	induction	NOUN
fnp-3766	323	5	of	of	ADP
fnp-3766	323	6	diffuse	diffuse	NOUN
fnp-3766	324	1	aβ	aβ	ADP
fnp-3766	324	2	deposition	deposition	NOUN
fnp-3766	324	3	by	by	ADP
fnp-3766	324	4	injection	injection	NOUN
fnp-3766	324	5	of	of	ADP
fnp-3766	324	6	four	four	NUM
fnp-3766	324	7	different	different	ADJ
fnp-3766	324	8	ad	ad	NOUN
fnp-3766	324	9	brain	brain	NOUN
fnp-3766	324	10	lysates	lysate	NOUN
fnp-3766	324	11	,	,	PUNCT
fnp-3766	324	12	and	and	CCONJ
fnp-3766	324	13	the	the	DET
fnp-3766	324	14	presence	presence	NOUN
fnp-3766	324	15	of	of	ADP
fnp-3766	324	16	tau	tau	PROPN
fnp-3766	324	17	seeds	seed	NOUN
fnp-3766	324	18	in	in	ADP
fnp-3766	324	19	these	these	DET
fnp-3766	324	20	lysates	lysate	NOUN
fnp-3766	324	21	,	,	PUNCT
fnp-3766	324	22	tau	tau	PROPN
fnp-3766	324	23	pathology	pathology	NOUN
fnp-3766	324	24	was	be	AUX
fnp-3766	324	25	not	not	PART
fnp-3766	324	26	induced	induce	VERB
fnp-3766	324	27	.	.	PUNCT
fnp-3766	325	1	for	for	ADP
fnp-3766	325	2	comparison	comparison	NOUN
fnp-3766	325	3	,	,	PUNCT
fnp-3766	325	4	we	we	PRON
fnp-3766	325	5	also	also	ADV
fnp-3766	325	6	injected	inject	VERB
fnp-3766	325	7	pa	pa	PROPN
fnp-3766	325	8	brain	brain	NOUN
fnp-3766	325	9	lysates	lysate	NOUN
fnp-3766	325	10	,	,	PUNCT
fnp-3766	325	11	finding	find	VERB
fnp-3766	325	12	a	a	DET
fnp-3766	325	13	similar	similar	ADJ
fnp-3766	325	14	induction	induction	NOUN
fnp-3766	325	15	of	of	ADP
fnp-3766	325	16	diffuse	diffuse	NOUN
fnp-3766	325	17	aβ	aβ	ADP
fnp-3766	325	18	deposition	deposition	NOUN
fnp-3766	325	19	without	without	ADP
fnp-3766	325	20	induction	induction	NOUN
fnp-3766	325	21	of	of	ADP
fnp-3766	325	22	tau	tau	PROPN
fnp-3766	325	23	pathology	pathology	PROPN
fnp-3766	325	24	.	.	PUNCT
fnp-3766	326	1	similarly	similarly	ADV
fnp-3766	326	2	,	,	PUNCT
fnp-3766	326	3	injection	injection	NOUN
fnp-3766	326	4	of	of	ADP
fnp-3766	326	5	ad	ad	NOUN
fnp-3766	326	6	/	/	SYM
fnp-3766	326	7	lbd	lbd	PROPN
fnp-3766	326	8	brain	brain	NOUN
fnp-3766	326	9	lysates	lysate	NOUN
fnp-3766	326	10	induced	induce	VERB
fnp-3766	326	11	diffuse	diffuse	NOUN
fnp-3766	326	12	aβ	aβ	ADP
fnp-3766	326	13	deposition	deposition	NOUN
fnp-3766	326	14	,	,	PUNCT
fnp-3766	326	15	but	but	CCONJ
fnp-3766	326	16	αsyn	αsyn	ADJ
fnp-3766	326	17	pathology	pathology	NOUN
fnp-3766	326	18	was	be	AUX
fnp-3766	326	19	not	not	PART
fnp-3766	326	20	induced	induce	VERB
fnp-3766	326	21	.	.	PUNCT
fnp-3766	327	1	in	in	ADP
fnp-3766	327	2	all	all	DET
fnp-3766	327	3	cases	case	NOUN
fnp-3766	327	4	,	,	PUNCT
fnp-3766	327	5	the	the	DET
fnp-3766	327	6	induced	induced	ADJ
fnp-3766	327	7	aβ	aβ	NOUN
fnp-3766	327	8	pathology	pathology	NOUN
fnp-3766	327	9	exhibited	exhibit	VERB
fnp-3766	327	10	a	a	DET
fnp-3766	327	11	diffuse	diffuse	NOUN
fnp-3766	327	12	,	,	PUNCT
fnp-3766	327	13	thio	thio	NOUN
fnp-3766	327	14	-	-	PUNCT
fnp-3766	327	15	s	s	NOUN
fnp-3766	327	16	negative	negative	ADJ
fnp-3766	327	17	,	,	PUNCT
fnp-3766	327	18	morphology	morphology	PROPN
fnp-3766	327	19	.	.	PUNCT
fnp-3766	328	1	prp.appsi	prp.appsi	PROPN
fnp-3766	328	2	mice	mouse	NOUN
fnp-3766	328	3	injected	inject	VERB
fnp-3766	328	4	with	with	ADP
fnp-3766	328	5	ad	ad	NOUN
fnp-3766	328	6	brain	brain	NOUN
fnp-3766	328	7	lysates	lysate	NOUN
fnp-3766	328	8	that	that	PRON
fnp-3766	328	9	develop	develop	VERB
fnp-3766	328	10	diffuse	diffuse	NOUN
fnp-3766	328	11	aβ	aβ	DET
fnp-3766	328	12	pathology	pathology	NOUN
fnp-3766	328	13	showed	show	VERB
fnp-3766	328	14	no	no	DET
fnp-3766	328	15	significant	significant	ADJ
fnp-3766	328	16	impairment	impairment	NOUN
fnp-3766	328	17	in	in	ADP
fnp-3766	328	18	a	a	DET
fnp-3766	328	19	fear	fear	NOUN
fnp-3766	328	20	-	-	PUNCT
fnp-3766	328	21	conditioning	condition	VERB
fnp-3766	328	22	cognitive	cognitive	ADJ
fnp-3766	328	23	task	task	NOUN
fnp-3766	328	24	.	.	PUNCT
fnp-3766	329	1	our	our	PRON
fnp-3766	329	2	findings	finding	NOUN
fnp-3766	329	3	suggest	suggest	VERB
fnp-3766	329	4	that	that	SCONJ
fnp-3766	329	5	seeding	seed	VERB
fnp-3766	329	6	the	the	DET
fnp-3766	329	7	brains	brain	NOUN
fnp-3766	329	8	of	of	ADP
fnp-3766	329	9	neonatal	neonatal	ADJ
fnp-3766	329	10	transgenic	transgenic	NOUN
fnp-3766	329	11	mice	mouse	NOUN
fnp-3766	329	12	with	with	ADP
fnp-3766	329	13	ad	ad	NOUN
fnp-3766	329	14	,	,	PUNCT
fnp-3766	329	15	ad	ad	NOUN
fnp-3766	329	16	/	/	SYM
fnp-3766	329	17	lbd	lbd	PROPN
fnp-3766	329	18	,	,	PUNCT
fnp-3766	329	19	and	and	CCONJ
fnp-3766	329	20	pa	pa	PROPN
fnp-3766	329	21	brain	brain	NOUN
fnp-3766	329	22	homogenates	homogenate	NOUN
fnp-3766	329	23	can	can	AUX
fnp-3766	329	24	efficiently	efficiently	ADV
fnp-3766	329	25	induce	induce	VERB
fnp-3766	329	26	diffuse	diffuse	NOUN
fnp-3766	329	27	aβ	aβ	ADP
fnp-3766	329	28	deposition	deposition	NOUN
fnp-3766	329	29	but	but	CCONJ
fnp-3766	329	30	neither	neither	CCONJ
fnp-3766	329	31	ad	ad	NOUN
fnp-3766	329	32	nor	nor	CCONJ
fnp-3766	329	33	ad	ad	NOUN
fnp-3766	329	34	/	/	SYM
fnp-3766	329	35	lbd	lbd	PROPN
fnp-3766	329	36	brains	brain	NOUN
fnp-3766	329	37	seeded	seed	VERB
fnp-3766	329	38	concurrent	concurrent	ADJ
fnp-3766	329	39	tau	tau	PROPN
fnp-3766	329	40	or	or	CCONJ
fnp-3766	329	41	αsyn	αsyn	ADJ
fnp-3766	329	42	pathology	pathology	NOUN
fnp-3766	329	43	.	.	PUNCT
fnp-3766	330	1	the	the	DET
fnp-3766	330	2	most	most	ADV
fnp-3766	330	3	common	common	ADJ
fnp-3766	330	4	route	route	NOUN
fnp-3766	330	5	of	of	ADP
fnp-3766	330	6	administering	administer	VERB
fnp-3766	330	7	aβ	aβ	NOUN
fnp-3766	330	8	seeding	seed	VERB
fnp-3766	330	9	preparations	preparation	NOUN
fnp-3766	330	10	is	be	AUX
fnp-3766	330	11	by	by	ADP
fnp-3766	330	12	stereotaxic	stereotaxic	ADJ
fnp-3766	330	13	injection	injection	NOUN
fnp-3766	330	14	into	into	ADP
fnp-3766	330	15	the	the	DET
fnp-3766	330	16	hippocampus	hippocampus	NOUN
fnp-3766	330	17	of	of	ADP
fnp-3766	330	18	adult	adult	NOUN
fnp-3766	330	19	app	app	NOUN
fnp-3766	330	20	transgenic	transgenic	NOUN
fnp-3766	330	21	mice	mouse	NOUN
fnp-3766	330	22	(	(	PUNCT
fnp-3766	330	23	reviewed	review	VERB
fnp-3766	330	24	in	in	ADP
fnp-3766	330	25	(	(	PUNCT
fnp-3766	330	26	13	13	NUM
fnp-3766	330	27	)	)	PUNCT
fnp-3766	330	28	)	)	PUNCT
fnp-3766	330	29	.	.	PUNCT
fnp-3766	331	1	in	in	ADP
fnp-3766	331	2	host	host	NOUN
fnp-3766	331	3	mice	mouse	NOUN
fnp-3766	331	4	that	that	PRON
fnp-3766	331	5	develop	develop	VERB
fnp-3766	331	6	amyloid	amyloid	NOUN
fnp-3766	331	7	pathology	pathology	NOUN
fnp-3766	331	8	at	at	ADP
fnp-3766	331	9	relatively	relatively	ADV
fnp-3766	331	10	young	young	ADJ
fnp-3766	331	11	ages	age	NOUN
fnp-3766	331	12	,	,	PUNCT
fnp-3766	331	13	the	the	DET
fnp-3766	331	14	induced	induced	ADJ
fnp-3766	331	15	pathology	pathology	NOUN
fnp-3766	331	16	created	create	VERB
fnp-3766	331	17	by	by	ADP
fnp-3766	331	18	seeding	seed	VERB
fnp-3766	331	19	may	may	AUX
fnp-3766	331	20	be	be	AUX
fnp-3766	331	21	localized	localize	VERB
fnp-3766	331	22	to	to	ADP
fnp-3766	331	23	the	the	DET
fnp-3766	331	24	site	site	NOUN
fnp-3766	331	25	of	of	ADP
fnp-3766	331	26	injection	injection	NOUN
fnp-3766	331	27	and	and	CCONJ
fnp-3766	331	28	overlying	overlie	VERB
fnp-3766	331	29	cortex	cortex	NOUN
fnp-3766	331	30	(	(	PUNCT
fnp-3766	331	31	13	13	NUM
fnp-3766	331	32	)	)	PUNCT
fnp-3766	331	33	;	;	PUNCT
fnp-3766	331	34	whereas	whereas	SCONJ
fnp-3766	331	35	,	,	PUNCT
fnp-3766	331	36	in	in	ADP
fnp-3766	331	37	models	model	NOUN
fnp-3766	331	38	that	that	PRON
fnp-3766	331	39	do	do	AUX
fnp-3766	331	40	not	not	PART
fnp-3766	331	41	develop	develop	VERB
fnp-3766	331	42	deposits	deposit	NOUN
fnp-3766	331	43	until	until	ADP
fnp-3766	331	44	late	late	ADV
fnp-3766	331	45	in	in	ADP
fnp-3766	331	46	life	life	NOUN
fnp-3766	331	47	,	,	PUNCT
fnp-3766	331	48	the	the	DET
fnp-3766	331	49	induced	induced	ADJ
fnp-3766	331	50	pathology	pathology	NOUN
fnp-3766	331	51	may	may	AUX
fnp-3766	331	52	be	be	AUX
fnp-3766	331	53	more	more	ADV
fnp-3766	331	54	wide	wide	ADV
fnp-3766	331	55	-	-	PUNCT
fnp-3766	331	56	spread	spread	NOUN
fnp-3766	331	57	(	(	PUNCT
fnp-3766	331	58	reviewed	review	VERB
fnp-3766	331	59	in	in	ADP
fnp-3766	331	60	(	(	PUNCT
fnp-3766	331	61	13	13	NUM
fnp-3766	331	62	)	)	PUNCT
fnp-3766	331	63	)	)	PUNCT
fnp-3766	331	64	.	.	PUNCT
fnp-3766	332	1	the	the	DET
fnp-3766	332	2	prp.appsi	prp.appsi	PROPN
fnp-3766	332	3	host	host	NOUN
fnp-3766	332	4	we	we	PRON
fnp-3766	332	5	used	use	VERB
fnp-3766	332	6	in	in	ADP
fnp-3766	332	7	the	the	DET
fnp-3766	332	8	present	present	ADJ
fnp-3766	332	9	study	study	NOUN
fnp-3766	332	10	develops	develop	VERB
fnp-3766	332	11	pathology	pathology	NOUN
fnp-3766	332	12	on	on	ADP
fnp-3766	332	13	its	its	PRON
fnp-3766	332	14	own	own	ADJ
fnp-3766	332	15	between	between	ADP
fnp-3766	332	16	12	12	NUM
fnp-3766	332	17	-	-	SYM
fnp-3766	332	18	14	14	NUM
fnp-3766	332	19	months	month	NOUN
fnp-3766	332	20	of	of	ADP
fnp-3766	332	21	age	age	NOUN
fnp-3766	332	22	.	.	PUNCT
fnp-3766	333	1	in	in	ADP
fnp-3766	333	2	testing	test	VERB
fnp-3766	333	3	the	the	DET
fnp-3766	333	4	approach	approach	NOUN
fnp-3766	333	5	of	of	ADP
fnp-3766	333	6	injecting	inject	VERB
fnp-3766	333	7	aβ	aβ	NOUN
fnp-3766	333	8	seeds	seed	NOUN
fnp-3766	333	9	into	into	ADP
fnp-3766	333	10	newborn	newborn	ADJ
fnp-3766	333	11	mice	mouse	NOUN
fnp-3766	333	12	from	from	ADP
fnp-3766	333	13	this	this	DET
fnp-3766	333	14	model	model	NOUN
fnp-3766	333	15	,	,	PUNCT
fnp-3766	333	16	we	we	PRON
fnp-3766	333	17	aspired	aspire	VERB
fnp-3766	333	18	to	to	PART
fnp-3766	333	19	attain	attain	VERB
fnp-3766	333	20	a	a	DET
fnp-3766	333	21	widespread	widespread	ADJ
fnp-3766	333	22	distribution	distribution	NOUN
fnp-3766	333	23	of	of	ADP
fnp-3766	333	24	seeding	seed	VERB
fnp-3766	333	25	material	material	NOUN
fnp-3766	333	26	and	and	CCONJ
fnp-3766	333	27	induce	induce	VERB
fnp-3766	333	28	aβ	aβ	PROPN
fnp-3766	333	29	,	,	PUNCT
fnp-3766	333	30	tau	tau	PROPN
fnp-3766	333	31	,	,	PUNCT
fnp-3766	333	32	or	or	CCONJ
fnp-3766	333	33	αsyn	αsyn	ADJ
fnp-3766	333	34	pathology	pathology	NOUN
fnp-3766	333	35	throughout	throughout	ADP
fnp-3766	333	36	the	the	DET
fnp-3766	333	37	brain	brain	NOUN
fnp-3766	333	38	.	.	PUNCT
fnp-3766	334	1	this	this	DET
fnp-3766	334	2	approach	approach	NOUN
fnp-3766	334	3	replicates	replicate	VERB
fnp-3766	334	4	previous	previous	ADJ
fnp-3766	334	5	studies	study	NOUN
fnp-3766	334	6	where	where	SCONJ
fnp-3766	334	7	p0	p0	NOUN
fnp-3766	334	8	injection	injection	NOUN
fnp-3766	334	9	of	of	ADP
fnp-3766	334	10	adeno	adeno	NOUN
fnp-3766	334	11	-	-	PUNCT
fnp-3766	334	12	associated	associate	VERB
fnp-3766	334	13	virus	virus	NOUN
fnp-3766	334	14	resulted	result	VERB
fnp-3766	334	15	in	in	ADP
fnp-3766	334	16	widespread	widespread	ADJ
fnp-3766	334	17	distribution	distribution	NOUN
fnp-3766	334	18	in	in	ADP
fnp-3766	334	19	the	the	DET
fnp-3766	334	20	brain	brain	NOUN
fnp-3766	334	21	(	(	PUNCT
fnp-3766	334	22	49	49	NUM
fnp-3766	334	23	)	)	PUNCT
fnp-3766	334	24	.	.	PUNCT
fnp-3766	335	1	injection	injection	NOUN
fnp-3766	335	2	of	of	ADP
fnp-3766	335	3	newborn	newborn	ADJ
fnp-3766	335	4	hamsters	hamster	NOUN
fnp-3766	335	5	with	with	ADP
fnp-3766	335	6	scrapie	scrapie	NOUN
fnp-3766	335	7	prions	prion	NOUN
fnp-3766	335	8	has	have	AUX
fnp-3766	335	9	been	be	AUX
fnp-3766	335	10	shown	show	VERB
fnp-3766	335	11	to	to	PART
fnp-3766	335	12	accelerate	accelerate	VERB
fnp-3766	335	13	onset	onset	NOUN
fnp-3766	335	14	of	of	ADP
fnp-3766	335	15	prion	prion	NOUN
fnp-3766	335	16	disease	disease	NOUN
fnp-3766	335	17	(	(	PUNCT
fnp-3766	335	18	50	50	NUM
fnp-3766	335	19	)	)	PUNCT
fnp-3766	335	20	.	.	PUNCT
fnp-3766	336	1	additionally	additionally	ADV
fnp-3766	336	2	,	,	PUNCT
fnp-3766	336	3	we	we	PRON
fnp-3766	336	4	have	have	AUX
fnp-3766	336	5	observed	observe	VERB
fnp-3766	336	6	that	that	SCONJ
fnp-3766	336	7	intracerebral	intracerebral	ADJ
fnp-3766	336	8	injection	injection	NOUN
fnp-3766	336	9	of	of	ADP
fnp-3766	336	10	newborn	newborn	ADJ
fnp-3766	336	11	a53	a53	PROPN
fnp-3766	336	12	t	t	PROPN
fnp-3766	336	13	αsyn	αsyn	ADJ
fnp-3766	336	14	mice	mouse	NOUN
fnp-3766	336	15	with	with	ADP
fnp-3766	336	16	brain	brain	NOUN
fnp-3766	336	17	lysates	lysate	NOUN
fnp-3766	336	18	from	from	ADP
fnp-3766	336	19	multiple	multiple	ADJ
fnp-3766	336	20	system	system	NOUN
fnp-3766	336	21	atrophy	atrophy	NOUN
fnp-3766	336	22	donors	donor	NOUN
fnp-3766	336	23	induces	induce	VERB
fnp-3766	336	24	αsyn	αsyn	ADJ
fnp-3766	336	25	pathology	pathology	NOUN
fnp-3766	336	26	and	and	CCONJ
fnp-3766	336	27	motor	motor	NOUN
fnp-3766	336	28	impairment	impairment	NOUN
fnp-3766	336	29	(	(	PUNCT
fnp-3766	336	30	31	31	NUM
fnp-3766	336	31	)	)	PUNCT
fnp-3766	336	32	,	,	PUNCT
fnp-3766	336	33	and	and	CCONJ
fnp-3766	336	34	that	that	SCONJ
fnp-3766	336	35	intraspinal	intraspinal	ADJ
fnp-3766	336	36	injection	injection	NOUN
fnp-3766	336	37	of	of	ADP
fnp-3766	336	38	newborn	newborn	ADJ
fnp-3766	336	39	mice	mouse	NOUN
fnp-3766	336	40	expressing	express	VERB
fnp-3766	336	41	mutant	mutant	ADJ
fnp-3766	336	42	superoxide	superoxide	NOUN
fnp-3766	336	43	dismutase	dismutase	NOUN
fnp-3766	336	44	(	(	PUNCT
fnp-3766	336	45	sod1	sod1	NOUN
fnp-3766	336	46	)	)	PUNCT
fnp-3766	336	47	can	can	AUX
fnp-3766	336	48	accelerate	accelerate	VERB
fnp-3766	336	49	the	the	DET
fnp-3766	336	50	onset	onset	NOUN
fnp-3766	336	51	of	of	ADP
fnp-3766	336	52	paralysis	paralysis	NOUN
fnp-3766	336	53	and	and	CCONJ
fnp-3766	336	54	pathology	pathology	NOUN
fnp-3766	336	55	(	(	PUNCT
fnp-3766	336	56	51	51	NUM
fnp-3766	336	57	,	,	PUNCT
fnp-3766	336	58	52	52	NUM
fnp-3766	336	59	)	)	PUNCT
fnp-3766	336	60	.	.	PUNCT
fnp-3766	337	1	thus	thus	ADV
fnp-3766	337	2	,	,	PUNCT
fnp-3766	337	3	in	in	ADP
fnp-3766	337	4	performing	perform	VERB
fnp-3766	337	5	newborn	newborn	ADJ
fnp-3766	337	6	injections	injection	NOUN
fnp-3766	337	7	our	our	PRON
fnp-3766	337	8	goal	goal	NOUN
fnp-3766	337	9	was	be	AUX
fnp-3766	337	10	to	to	PART
fnp-3766	337	11	initiate	initiate	VERB
fnp-3766	337	12	pathological	pathological	ADJ
fnp-3766	337	13	cascades	cascade	NOUN
fnp-3766	337	14	as	as	ADV
fnp-3766	337	15	early	early	ADV
fnp-3766	337	16	as	as	ADP
fnp-3766	337	17	possible	possible	ADJ
fnp-3766	337	18	in	in	ADP
fnp-3766	337	19	order	order	NOUN
fnp-3766	337	20	to	to	PART
fnp-3766	337	21	determine	determine	VERB
fnp-3766	337	22	whether	whether	SCONJ
fnp-3766	337	23	there	there	PRON
fnp-3766	337	24	may	may	AUX
fnp-3766	337	25	be	be	AUX
fnp-3766	337	26	distinct	distinct	ADJ
fnp-3766	337	27	synergies	synergy	NOUN
fnp-3766	337	28	between	between	ADP
fnp-3766	337	29	aβ	aβ	NOUN
fnp-3766	337	30	and	and	CCONJ
fnp-3766	337	31	tau	tau	PROPN
fnp-3766	337	32	,	,	PUNCT
fnp-3766	337	33	or	or	CCONJ
fnp-3766	337	34	aβ	aβ	NOUN
fnp-3766	337	35	and	and	CCONJ
fnp-3766	337	36	αsyn	αsyn	PROPN
fnp-3766	337	37	,	,	PUNCT
fnp-3766	337	38	which	which	PRON
fnp-3766	337	39	can	can	AUX
fnp-3766	337	40	be	be	AUX
fnp-3766	337	41	elaborated	elaborate	VERB
fnp-3766	337	42	by	by	ADP
fnp-3766	337	43	seeding	seed	VERB
fnp-3766	337	44	.	.	PUNCT
fnp-3766	338	1	we	we	PRON
fnp-3766	338	2	recognize	recognize	VERB
fnp-3766	338	3	that	that	SCONJ
fnp-3766	338	4	there	there	PRON
fnp-3766	338	5	are	be	VERB
fnp-3766	338	6	a	a	DET
fnp-3766	338	7	large	large	ADJ
fnp-3766	338	8	number	number	NOUN
fnp-3766	338	9	of	of	ADP
fnp-3766	338	10	potential	potential	ADJ
fnp-3766	338	11	mouse	mouse	NOUN
fnp-3766	338	12	models	model	NOUN
fnp-3766	338	13	that	that	PRON
fnp-3766	338	14	could	could	AUX
fnp-3766	338	15	have	have	AUX
fnp-3766	338	16	been	be	AUX
fnp-3766	338	17	used	use	VERB
fnp-3766	338	18	for	for	ADP
fnp-3766	338	19	these	these	DET
fnp-3766	338	20	studies	study	NOUN
fnp-3766	338	21	.	.	PUNCT
fnp-3766	339	1	the	the	DET
fnp-3766	339	2	app	app	PROPN
fnp-3766	339	3	mouse	mouse	PROPN
fnp-3766	339	4	model	model	NOUN
fnp-3766	339	5	we	we	PRON
fnp-3766	339	6	used	use	VERB
fnp-3766	339	7	for	for	ADP
fnp-3766	339	8	these	these	DET
fnp-3766	339	9	studies	study	NOUN
fnp-3766	339	10	was	be	AUX
fnp-3766	339	11	selected	select	VERB
fnp-3766	339	12	because	because	SCONJ
fnp-3766	339	13	prp.appsi	prp.appsi	NUM
fnp-3766	339	14	mice	mouse	NOUN
fnp-3766	339	15	do	do	AUX
fnp-3766	339	16	not	not	PART
fnp-3766	339	17	inherently	inherently	ADV
fnp-3766	339	18	develop	develop	VERB
fnp-3766	339	19	aβ	aβ	DET
fnp-3766	339	20	pathology	pathology	NOUN
fnp-3766	339	21	until	until	ADP
fnp-3766	339	22	12	12	NUM
fnp-3766	339	23	-	-	SYM
fnp-3766	339	24	14	14	NUM
fnp-3766	339	25	months	month	NOUN
fnp-3766	339	26	of	of	ADP
fnp-3766	339	27	age	age	NOUN
fnp-3766	339	28	and	and	CCONJ
fnp-3766	339	29	because	because	SCONJ
fnp-3766	339	30	this	this	DET
fnp-3766	339	31	model	model	NOUN
fnp-3766	339	32	can	can	AUX
fnp-3766	339	33	exhibit	exhibit	VERB
fnp-3766	339	34	a	a	DET
fnp-3766	339	35	full	full	ADJ
fnp-3766	339	36	spectrum	spectrum	NOUN
fnp-3766	339	37	of	of	ADP
fnp-3766	339	38	aβ	aβ	DET
fnp-3766	339	39	pathology	pathology	NOUN
fnp-3766	339	40	including	include	VERB
fnp-3766	339	41	cored	core	VERB
fnp-3766	339	42	-	-	PUNCT
fnp-3766	339	43	neuritic	neuritic	ADJ
fnp-3766	339	44	,	,	PUNCT
fnp-3766	339	45	diffuse	diffuse	NOUN
fnp-3766	339	46	,	,	PUNCT
fnp-3766	339	47	and	and	CCONJ
fnp-3766	339	48	vascular	vascular	ADJ
fnp-3766	339	49	deposition	deposition	NOUN
fnp-3766	339	50	(	(	PUNCT
fnp-3766	339	51	see	see	VERB
fnp-3766	339	52	supplemental	supplemental	ADJ
fnp-3766	339	53	fig	fig	NOUN
fnp-3766	339	54	.	.	PUNCT
fnp-3766	340	1	s2	s2	PROPN
fnp-3766	340	2	)	)	PUNCT
fnp-3766	340	3	.	.	PUNCT
fnp-3766	341	1	the	the	DET
fnp-3766	341	2	tau	tau	PROPN
fnp-3766	341	3	model	model	NOUN
fnp-3766	341	4	we	we	PRON
fnp-3766	341	5	chose	choose	VERB
fnp-3766	341	6	to	to	PART
fnp-3766	341	7	use	use	VERB
fnp-3766	341	8	expresses	express	NOUN
fnp-3766	341	9	human	human	ADJ
fnp-3766	341	10	p301l	p301l	PROPN
fnp-3766	341	11	tau	tau	PROPN
fnp-3766	341	12	at	at	ADP
fnp-3766	341	13	relatively	relatively	ADV
fnp-3766	341	14	low	low	ADJ
fnp-3766	341	15	levels	level	NOUN
fnp-3766	341	16	and	and	CCONJ
fnp-3766	341	17	does	do	AUX
fnp-3766	341	18	not	not	PART
fnp-3766	341	19	develop	develop	VERB
fnp-3766	341	20	tau	tau	PROPN
fnp-3766	341	21	pathology	pathology	NOUN
fnp-3766	341	22	on	on	ADP
fnp-3766	341	23	its	its	PRON
fnp-3766	341	24	own	own	ADJ
fnp-3766	341	25	.	.	PUNCT
fnp-3766	342	1	when	when	SCONJ
fnp-3766	342	2	paired	pair	VERB
fnp-3766	342	3	with	with	ADP
fnp-3766	342	4	mice	mouse	NOUN
fnp-3766	342	5	that	that	PRON
fnp-3766	342	6	express	express	VERB
fnp-3766	342	7	the	the	DET
fnp-3766	342	8	tetracycline	tetracycline	ADJ
fnp-3766	342	9	transactivator	transactivator	NOUN
fnp-3766	342	10	in	in	ADP
fnp-3766	342	11	the	the	DET
fnp-3766	342	12	rtg4510	rtg4510	ADJ
fnp-3766	342	13	model	model	NOUN
fnp-3766	342	14	these	these	PRON
fnp-3766	342	15	develop	develop	VERB
fnp-3766	342	16	a	a	DET
fnp-3766	342	17	robust	robust	ADJ
fnp-3766	342	18	tau	tau	NOUN
fnp-3766	342	19	pathology	pathology	NOUN
fnp-3766	342	20	(	(	PUNCT
fnp-3766	342	21	38	38	NUM
fnp-3766	342	22	)	)	PUNCT
fnp-3766	342	23	.	.	PUNCT
fnp-3766	343	1	in	in	ADP
fnp-3766	343	2	paradigms	paradigm	NOUN
fnp-3766	343	3	in	in	ADP
fnp-3766	343	4	which	which	PRON
fnp-3766	343	5	tau	tau	PROPN
fnp-3766	343	6	expression	expression	NOUN
fnp-3766	343	7	in	in	ADP
fnp-3766	343	8	rtg4510	rtg4510	ADJ
fnp-3766	343	9	mice	mouse	NOUN
fnp-3766	343	10	is	be	AUX
fnp-3766	343	11	induced	induce	VERB
fnp-3766	343	12	early	early	ADV
fnp-3766	343	13	and	and	CCONJ
fnp-3766	343	14	then	then	ADV
fnp-3766	343	15	suppressed	suppress	VERB
fnp-3766	343	16	by	by	ADP
fnp-3766	343	17	doxycycline	doxycycline	NOUN
fnp-3766	343	18	,	,	PUNCT
fnp-3766	343	19	the	the	DET
fnp-3766	343	20	low	low	ADJ
fnp-3766	343	21	level	level	NOUN
fnp-3766	343	22	of	of	ADP
fnp-3766	343	23	“	"	PUNCT
fnp-3766	343	24	leaky	leaky	ADJ
fnp-3766	343	25	”	"	PUNCT
fnp-3766	343	26	tau	tau	NOUN
fnp-3766	343	27	expression	expression	NOUN
fnp-3766	343	28	in	in	ADP
fnp-3766	343	29	this	this	DET
fnp-3766	343	30	model	model	NOUN
fnp-3766	343	31	is	be	AUX
fnp-3766	343	32	sufficient	sufficient	ADJ
fnp-3766	343	33	to	to	PART
fnp-3766	343	34	sustain	sustain	VERB
fnp-3766	343	35	neurofibrillary	neurofibrillary	ADJ
fnp-3766	343	36	tangle	tangle	NOUN
fnp-3766	343	37	pathology	pathology	NOUN
fnp-3766	343	38	(	(	PUNCT
fnp-3766	343	39	38	38	NUM
fnp-3766	343	40	)	)	PUNCT
fnp-3766	343	41	.	.	PUNCT
fnp-3766	344	1	in	in	ADP
fnp-3766	344	2	our	our	PRON
fnp-3766	344	3	paradigm	paradigm	NOUN
fnp-3766	344	4	,	,	PUNCT
fnp-3766	344	5	we	we	PRON
fnp-3766	344	6	asked	ask	VERB
fnp-3766	344	7	whether	whether	SCONJ
fnp-3766	344	8	neonatal	neonatal	ADJ
fnp-3766	344	9	seeding	seeding	NOUN
fnp-3766	344	10	of	of	ADP
fnp-3766	344	11	this	this	DET
fnp-3766	344	12	tau	tau	PROPN
fnp-3766	344	13	model	model	NOUN
fnp-3766	344	14	could	could	AUX
fnp-3766	344	15	induce	induce	VERB
fnp-3766	344	16	a	a	DET
fnp-3766	344	17	sustained	sustained	ADJ
fnp-3766	344	18	pathology	pathology	NOUN
fnp-3766	344	19	in	in	ADP
fnp-3766	344	20	the	the	DET
fnp-3766	344	21	same	same	ADJ
fnp-3766	344	22	way	way	NOUN
fnp-3766	344	23	that	that	PRON
fnp-3766	344	24	early	early	ADJ
fnp-3766	344	25	expression	expression	NOUN
fnp-3766	344	26	of	of	ADP
fnp-3766	344	27	the	the	DET
fnp-3766	344	28	transgene	transgene	NOUN
fnp-3766	344	29	at	at	ADP
fnp-3766	344	30	high	high	ADJ
fnp-3766	344	31	levels	level	NOUN
fnp-3766	344	32	produced	produce	VERB
fnp-3766	344	33	sustained	sustained	ADJ
fnp-3766	344	34	pathology	pathology	NOUN
fnp-3766	344	35	.	.	PUNCT
fnp-3766	345	1	alternatively	alternatively	ADV
fnp-3766	345	2	,	,	PUNCT
fnp-3766	345	3	we	we	PRON
fnp-3766	345	4	were	be	AUX
fnp-3766	345	5	interested	interested	ADJ
fnp-3766	345	6	to	to	PART
fnp-3766	345	7	determine	determine	VERB
fnp-3766	345	8	whether	whether	SCONJ
fnp-3766	345	9	we	we	PRON
fnp-3766	345	10	could	could	AUX
fnp-3766	345	11	detect	detect	VERB
fnp-3766	345	12	any	any	DET
fnp-3766	345	13	synergy	synergy	NOUN
fnp-3766	345	14	between	between	ADP
fnp-3766	345	15	concurrent	concurrent	ADJ
fnp-3766	345	16	aβ	aβ	PRON
fnp-3766	345	17	pathology	pathology	NOUN
fnp-3766	345	18	and	and	CCONJ
fnp-3766	345	19	tau	tau	PROPN
fnp-3766	345	20	seeding	seeding	NOUN
fnp-3766	345	21	.	.	PUNCT
fnp-3766	346	1	the	the	DET
fnp-3766	346	2	αsyn	αsyn	PROPN
fnp-3766	346	3	model	model	NOUN
fnp-3766	346	4	we	we	PRON
fnp-3766	346	5	chose	choose	VERB
fnp-3766	346	6	to	to	PART
fnp-3766	346	7	use	use	VERB
fnp-3766	346	8	expresses	express	NOUN
fnp-3766	346	9	human	human	ADJ
fnp-3766	346	10	wt	wt	PROPN
fnp-3766	346	11	αsyn	αsyn	NOUN
fnp-3766	346	12	at	at	ADP
fnp-3766	346	13	levels	level	NOUN
fnp-3766	346	14	that	that	PRON
fnp-3766	346	15	do	do	AUX
fnp-3766	346	16	not	not	PART
fnp-3766	346	17	cause	cause	VERB
fnp-3766	346	18	pathology	pathology	NOUN
fnp-3766	346	19	(	(	PUNCT
fnp-3766	346	20	41	41	NUM
fnp-3766	346	21	)	)	PUNCT
fnp-3766	346	22	.	.	PUNCT
fnp-3766	347	1	wt	wt	PROPN
fnp-3766	347	2	αsyn	αsyn	PROPN
fnp-3766	347	3	(	(	PUNCT
fnp-3766	347	4	m20	m20	NOUN
fnp-3766	347	5	)	)	PUNCT
fnp-3766	347	6	mice	mouse	NOUN
fnp-3766	347	7	can	can	AUX
fnp-3766	347	8	be	be	AUX
fnp-3766	347	9	seeded	seed	VERB
fnp-3766	347	10	when	when	SCONJ
fnp-3766	347	11	injected	inject	VERB
fnp-3766	347	12	with	with	ADP
fnp-3766	347	13	high	high	ADJ
fnp-3766	347	14	levels	level	NOUN
fnp-3766	347	15	of	of	ADP
fnp-3766	347	16	purified	purified	ADJ
fnp-3766	347	17	αsyn	αsyn	ADJ
fnp-3766	347	18	fibrils	fibril	NOUN
fnp-3766	347	19	,	,	PUNCT
fnp-3766	347	20	but	but	CCONJ
fnp-3766	347	21	are	be	AUX
fnp-3766	347	22	not	not	PART
fnp-3766	347	23	easily	easily	ADV
fnp-3766	347	24	seeded	seed	VERB
fnp-3766	347	25	by	by	ADP
fnp-3766	347	26	human	human	ADJ
fnp-3766	347	27	brain	brain	NOUN
fnp-3766	347	28	homogenates	homogenate	NOUN
fnp-3766	347	29	(	(	PUNCT
fnp-3766	347	30	31	31	NUM
fnp-3766	347	31	)	)	PUNCT
fnp-3766	347	32	.	.	PUNCT
fnp-3766	348	1	our	our	PRON
fnp-3766	348	2	goal	goal	NOUN
fnp-3766	348	3	in	in	ADP
fnp-3766	348	4	choosing	choose	VERB
fnp-3766	348	5	the	the	DET
fnp-3766	348	6	m20	m20	PROPN
fnp-3766	348	7	wt	wt	PROPN
fnp-3766	348	8	αsyn	αsyn	PROPN
fnp-3766	348	9	mice	mouse	NOUN
fnp-3766	348	10	was	be	AUX
fnp-3766	348	11	to	to	PART
fnp-3766	348	12	develop	develop	VERB
fnp-3766	348	13	a	a	DET
fnp-3766	348	14	model	model	NOUN
fnp-3766	348	15	of	of	ADP
fnp-3766	348	16	human	human	ADJ
fnp-3766	348	17	αsyn	αsyn	PROPN
fnp-3766	348	18	pathology	pathology	NOUN
fnp-3766	348	19	and	and	CCONJ
fnp-3766	348	20	assess	assess	VERB
fnp-3766	348	21	whether	whether	SCONJ
fnp-3766	348	22	concurrent	concurrent	ADJ
fnp-3766	348	23	aβ	aβ	DET
fnp-3766	348	24	pathology	pathology	NOUN
fnp-3766	348	25	could	could	AUX
fnp-3766	348	26	synergize	synergize	VERB
fnp-3766	348	27	αsyn	αsyn	ADJ
fnp-3766	348	28	seeding	seeding	NOUN
fnp-3766	348	29	.	.	PUNCT
fnp-3766	349	1	our	our	PRON
fnp-3766	349	2	method	method	NOUN
fnp-3766	349	3	of	of	ADP
fnp-3766	349	4	seed	seed	NOUN
fnp-3766	349	5	preparation	preparation	NOUN
fnp-3766	349	6	followed	follow	VERB
fnp-3766	349	7	commonly	commonly	ADV
fnp-3766	349	8	used	use	VERB
fnp-3766	349	9	protocols	protocol	NOUN
fnp-3766	349	10	where	where	SCONJ
fnp-3766	349	11	we	we	PRON
fnp-3766	349	12	injected	inject	VERB
fnp-3766	349	13	a	a	DET
fnp-3766	349	14	soluble	soluble	ADJ
fnp-3766	349	15	fraction	fraction	NOUN
fnp-3766	349	16	;	;	PUNCT
fnp-3766	349	17	frontal	frontal	ADJ
fnp-3766	349	18	cortex	cortex	NOUN
fnp-3766	349	19	homogenized	homogenize	VERB
fnp-3766	349	20	in	in	ADP
fnp-3766	349	21	pbs	pbs	PROPN
fnp-3766	349	22	(	(	PUNCT
fnp-3766	349	23	10	10	NUM
fnp-3766	349	24	%	%	NOUN
fnp-3766	349	25	w	w	NOUN
fnp-3766	349	26	/	/	SYM
fnp-3766	349	27	v	v	NOUN
fnp-3766	349	28	)	)	PUNCT
fnp-3766	349	29	followed	follow	VERB
fnp-3766	349	30	by	by	ADP
fnp-3766	349	31	sonication	sonication	NOUN
fnp-3766	349	32	and	and	CCONJ
fnp-3766	349	33	low	low	ADJ
fnp-3766	349	34	speed	speed	NOUN
fnp-3766	349	35	centrifugation	centrifugation	NOUN
fnp-3766	349	36	,	,	PUNCT
fnp-3766	349	37	as	as	SCONJ
fnp-3766	349	38	previously	previously	ADV
fnp-3766	349	39	described	describe	VERB
fnp-3766	349	40	(	(	PUNCT
fnp-3766	349	41	42	42	NUM
fnp-3766	349	42	,	,	PUNCT
fnp-3766	349	43	53	53	NUM
fnp-3766	349	44	,	,	PUNCT
fnp-3766	349	45	54	54	NUM
fnp-3766	349	46	)	)	PUNCT
fnp-3766	349	47	.	.	PUNCT
fnp-3766	350	1	by	by	ADP
fnp-3766	350	2	this	this	DET
fnp-3766	350	3	method	method	NOUN
fnp-3766	350	4	,	,	PUNCT
fnp-3766	350	5	we	we	PRON
fnp-3766	350	6	expected	expect	VERB
fnp-3766	350	7	sonication	sonication	NOUN
fnp-3766	350	8	to	to	PART
fnp-3766	350	9	fragment	fragment	VERB
fnp-3766	350	10	all	all	DET
fnp-3766	350	11	types	type	NOUN
fnp-3766	350	12	of	of	ADP
fnp-3766	350	13	seeds	seed	NOUN
fnp-3766	350	14	with	with	ADP
fnp-3766	350	15	a	a	DET
fnp-3766	350	16	mixture	mixture	NOUN
fnp-3766	350	17	of	of	ADP
fnp-3766	350	18	seeds	seed	NOUN
fnp-3766	350	19	remaining	remain	VERB
fnp-3766	350	20	in	in	ADP
fnp-3766	350	21	suspension	suspension	NOUN
fnp-3766	350	22	after	after	ADP
fnp-3766	350	23	low	low	ADJ
fnp-3766	350	24	-	-	PUNCT
fnp-3766	350	25	speed	speed	NOUN
fnp-3766	350	26	centrifugation	centrifugation	NOUN
fnp-3766	350	27	.	.	PUNCT
fnp-3766	351	1	as	as	SCONJ
fnp-3766	351	2	we	we	PRON
fnp-3766	351	3	have	have	AUX
fnp-3766	351	4	observed	observe	VERB
fnp-3766	351	5	here	here	ADV
fnp-3766	351	6	,	,	PUNCT
fnp-3766	351	7	the	the	DET
fnp-3766	351	8	most	most	ADV
fnp-3766	351	9	common	common	ADJ
fnp-3766	351	10	outcome	outcome	NOUN
fnp-3766	351	11	of	of	ADP
fnp-3766	351	12	aβ	aβ	NOUN
fnp-3766	351	13	seeding	seed	VERB
fnp-3766	351	14	with	with	ADP
fnp-3766	351	15	similar	similar	ADJ
fnp-3766	351	16	preparations	preparation	NOUN
fnp-3766	351	17	is	be	AUX
fnp-3766	351	18	induction	induction	NOUN
fnp-3766	351	19	of	of	ADP
fnp-3766	351	20	diffuse	diffuse	NOUN
fnp-3766	351	21	aβ	aβ	PRON
fnp-3766	351	22	pathology	pathology	NOUN
fnp-3766	351	23	(	(	PUNCT
fnp-3766	351	24	reviewed	review	VERB
fnp-3766	351	25	in	in	ADP
fnp-3766	351	26	(	(	PUNCT
fnp-3766	351	27	13	13	NUM
fnp-3766	351	28	)	)	PUNCT
fnp-3766	351	29	)	)	PUNCT
fnp-3766	351	30	.	.	PUNCT
fnp-3766	352	1	in	in	ADP
fnp-3766	352	2	order	order	NOUN
fnp-3766	352	3	to	to	PART
fnp-3766	352	4	efficiently	efficiently	ADV
fnp-3766	352	5	seed	seed	VERB
fnp-3766	352	6	mixed	mixed	ADJ
fnp-3766	352	7	pathology	pathology	NOUN
fnp-3766	352	8	,	,	PUNCT
fnp-3766	352	9	it	it	PRON
fnp-3766	352	10	may	may	AUX
fnp-3766	352	11	be	be	AUX
fnp-3766	352	12	necessary	necessary	ADJ
fnp-3766	352	13	to	to	PART
fnp-3766	352	14	optimize	optimize	VERB
fnp-3766	352	15	preparations	preparation	NOUN
fnp-3766	352	16	of	of	ADP
fnp-3766	352	17	each	each	DET
fnp-3766	352	18	type	type	NOUN
fnp-3766	352	19	of	of	ADP
fnp-3766	352	20	seed	seed	NOUN
fnp-3766	352	21	independently	independently	ADV
fnp-3766	352	22	.	.	PUNCT
fnp-3766	353	1	interestingly	interestingly	ADV
fnp-3766	353	2	,	,	PUNCT
fnp-3766	353	3	injection	injection	NOUN
fnp-3766	353	4	of	of	ADP
fnp-3766	353	5	the	the	DET
fnp-3766	353	6	supernatant	supernatant	NOUN
fnp-3766	353	7	and	and	CCONJ
fnp-3766	353	8	pellet	pellet	NOUN
fnp-3766	353	9	of	of	ADP
fnp-3766	353	10	fractionated	fractionate	VERB
fnp-3766	353	11	app23	app23	PROPN
fnp-3766	353	12	brain	brain	NOUN
fnp-3766	353	13	homogenate	homogenate	NOUN
fnp-3766	353	14	resulted	result	VERB
fnp-3766	353	15	in	in	ADP
fnp-3766	353	16	morphologically	morphologically	ADV
fnp-3766	353	17	different	different	ADJ
fnp-3766	353	18	aβ	aβ	ADP
fnp-3766	353	19	deposits	deposit	NOUN
fnp-3766	353	20	,	,	PUNCT
fnp-3766	353	21	with	with	ADP
fnp-3766	353	22	the	the	DET
fnp-3766	353	23	supernatant	supernatant	NOUN
fnp-3766	353	24	fraction	fraction	NOUN
fnp-3766	353	25	seeding	seed	VERB
fnp-3766	353	26	diffuse	diffuse	NOUN
fnp-3766	353	27	,	,	PUNCT
fnp-3766	353	28	congo	congo	PROPN
fnp-3766	353	29	red	red	ADJ
fnp-3766	353	30	negative	negative	PROPN
fnp-3766	353	31	aβ	aβ	ADP
fnp-3766	353	32	and	and	CCONJ
fnp-3766	353	33	the	the	DET
fnp-3766	353	34	pellet	pellet	NOUN
fnp-3766	353	35	seeding	seed	VERB
fnp-3766	353	36	deposits	deposit	NOUN
fnp-3766	353	37	similar	similar	ADJ
fnp-3766	353	38	to	to	ADP
fnp-3766	353	39	the	the	DET
fnp-3766	353	40	total	total	ADJ
fnp-3766	353	41	lysate	lysate	NOUN
fnp-3766	353	42	,	,	PUNCT
fnp-3766	353	43	a	a	DET
fnp-3766	353	44	mixture	mixture	NOUN
fnp-3766	353	45	of	of	ADP
fnp-3766	353	46	diffuse	diffuse	NOUN
fnp-3766	353	47	and	and	CCONJ
fnp-3766	353	48	punctate	punctate	NOUN
fnp-3766	353	49	,	,	PUNCT
fnp-3766	353	50	congo	congo	NOUN
fnp-3766	353	51	red	red	VERB
fnp-3766	353	52	positive	positive	ADJ
fnp-3766	353	53	deposits	deposit	NOUN
fnp-3766	353	54	(	(	PUNCT
fnp-3766	353	55	55	55	NUM
fnp-3766	353	56	)	)	PUNCT
fnp-3766	353	57	.	.	PUNCT
fnp-3766	354	1	several	several	ADJ
fnp-3766	354	2	studies	study	NOUN
fnp-3766	354	3	have	have	AUX
fnp-3766	354	4	shown	show	VERB
fnp-3766	354	5	induction	induction	NOUN
fnp-3766	354	6	of	of	ADP
fnp-3766	354	7	tau	tau	PROPN
fnp-3766	354	8	pathology	pathology	NOUN
fnp-3766	354	9	after	after	ADP
fnp-3766	354	10	injection	injection	NOUN
fnp-3766	354	11	of	of	ADP
fnp-3766	354	12	synthetic	synthetic	ADJ
fnp-3766	354	13	tau	tau	PROPN
fnp-3766	354	14	fibrils	fibril	NOUN
fnp-3766	354	15	,	,	PUNCT
fnp-3766	354	16	brain	brain	NOUN
fnp-3766	354	17	extract	extract	NOUN
fnp-3766	354	18	from	from	ADP
fnp-3766	354	19	mutant	mutant	ADJ
fnp-3766	354	20	p301s	p301s	PROPN
fnp-3766	354	21	tau	tau	PROPN
fnp-3766	354	22	mouse	mouse	NOUN
fnp-3766	354	23	,	,	PUNCT
fnp-3766	354	24	or	or	CCONJ
fnp-3766	354	25	human	human	ADJ
fnp-3766	354	26	ad	ad	NOUN
fnp-3766	354	27	,	,	PUNCT
fnp-3766	354	28	corticobasal	corticobasal	NOUN
fnp-3766	354	29	degeneration	degeneration	NOUN
fnp-3766	354	30	,	,	PUNCT
fnp-3766	354	31	and	and	CCONJ
fnp-3766	354	32	progressive	progressive	ADJ
fnp-3766	354	33	supranuclear	supranuclear	ADJ
fnp-3766	354	34	palsy	palsy	ADJ
fnp-3766	354	35	brain	brain	NOUN
fnp-3766	354	36	lysates	lysate	NOUN
fnp-3766	354	37	(	(	PUNCT
fnp-3766	354	38	56	56	NUM
fnp-3766	354	39	-	-	SYM
fnp-3766	354	40	62	62	NUM
fnp-3766	354	41	)	)	PUNCT
fnp-3766	354	42	.	.	PUNCT
fnp-3766	355	1	in	in	ADP
fnp-3766	355	2	these	these	DET
fnp-3766	355	3	studies	study	NOUN
fnp-3766	355	4	,	,	PUNCT
fnp-3766	355	5	the	the	DET
fnp-3766	355	6	human	human	ADJ
fnp-3766	355	7	brain	brain	NOUN
fnp-3766	355	8	lysates	lysate	NOUN
fnp-3766	355	9	were	be	AUX
fnp-3766	355	10	enriched	enrich	VERB
fnp-3766	355	11	for	for	ADP
fnp-3766	355	12	tau	tau	PROPN
fnp-3766	355	13	seeds	seed	NOUN
fnp-3766	355	14	by	by	ADP
fnp-3766	355	15	sequential	sequential	ADJ
fnp-3766	355	16	fractionation	fractionation	NOUN
fnp-3766	355	17	with	with	ADP
fnp-3766	355	18	the	the	DET
fnp-3766	355	19	addition	addition	NOUN
fnp-3766	355	20	of	of	ADP
fnp-3766	355	21	sucrose	sucrose	NOUN
fnp-3766	355	22	and/or	and/or	CCONJ
fnp-3766	355	23	sarkosyl	sarkosyl	NOUN
fnp-3766	355	24	,	,	PUNCT
fnp-3766	355	25	creating	create	VERB
fnp-3766	355	26	fractions	fraction	NOUN
fnp-3766	355	27	that	that	PRON
fnp-3766	355	28	contain	contain	VERB
fnp-3766	355	29	potent	potent	ADJ
fnp-3766	355	30	tau	tau	NOUN
fnp-3766	355	31	seeds	seed	NOUN
fnp-3766	355	32	.	.	PUNCT
fnp-3766	356	1	similarly	similarly	ADV
fnp-3766	356	2	,	,	PUNCT
fnp-3766	356	3	injection	injection	NOUN
fnp-3766	356	4	of	of	ADP
fnp-3766	356	5	the	the	DET
fnp-3766	356	6	fractionated	fractionated	ADJ
fnp-3766	356	7	homogenate	homogenate	NOUN
fnp-3766	356	8	from	from	ADP
fnp-3766	356	9	brain	brain	NOUN
fnp-3766	356	10	lysates	lysate	NOUN
fnp-3766	356	11	of	of	ADP
fnp-3766	356	12	individuals	individual	NOUN
fnp-3766	356	13	with	with	ADP
fnp-3766	356	14	lbd	lbd	PROPN
fnp-3766	356	15	resulted	result	VERB
fnp-3766	356	16	in	in	ADP
fnp-3766	356	17	the	the	DET
fnp-3766	356	18	induction	induction	NOUN
fnp-3766	356	19	of	of	ADP
fnp-3766	356	20	αsyn	αsyn	PROPN
fnp-3766	356	21	,	,	PUNCT
fnp-3766	356	22	indicating	indicate	VERB
fnp-3766	356	23	that	that	SCONJ
fnp-3766	356	24	with	with	ADP
fnp-3766	356	25	enrichment	enrichment	NOUN
fnp-3766	356	26	it	it	PRON
fnp-3766	356	27	is	be	AUX
fnp-3766	356	28	possible	possible	ADJ
fnp-3766	356	29	to	to	PART
fnp-3766	356	30	seed	seed	VERB
fnp-3766	356	31	αsyn	αsyn	ADJ
fnp-3766	356	32	pathology	pathology	NOUN
fnp-3766	356	33	directly	directly	ADV
fnp-3766	356	34	from	from	ADP
fnp-3766	356	35	human	human	ADJ
fnp-3766	356	36	brain	brain	NOUN
fnp-3766	356	37	(	(	PUNCT
fnp-3766	356	38	20	20	NUM
fnp-3766	356	39	,	,	PUNCT
fnp-3766	356	40	63	63	NUM
fnp-3766	356	41	,	,	PUNCT
fnp-3766	356	42	64	64	NUM
fnp-3766	356	43	)	)	PUNCT
fnp-3766	356	44	.	.	PUNCT
fnp-3766	357	1	because	because	SCONJ
fnp-3766	357	2	one	one	NUM
fnp-3766	357	3	of	of	ADP
fnp-3766	357	4	our	our	PRON
fnp-3766	357	5	goals	goal	NOUN
fnp-3766	357	6	was	be	AUX
fnp-3766	357	7	to	to	PART
fnp-3766	357	8	determine	determine	VERB
fnp-3766	357	9	whether	whether	SCONJ
fnp-3766	357	10	we	we	PRON
fnp-3766	357	11	could	could	AUX
fnp-3766	357	12	detect	detect	VERB
fnp-3766	357	13	synergy	synergy	NOUN
fnp-3766	357	14	between	between	ADP
fnp-3766	357	15	aβ	aβ	NOUN
fnp-3766	357	16	and	and	CCONJ
fnp-3766	357	17	tau	tau	PROPN
fnp-3766	357	18	or	or	CCONJ
fnp-3766	357	19	αsyn	αsyn	PROPN
fnp-3766	357	20	pathology	pathology	NOUN
fnp-3766	357	21	,	,	PUNCT
fnp-3766	357	22	we	we	PRON
fnp-3766	357	23	chose	choose	VERB
fnp-3766	357	24	to	to	PART
fnp-3766	357	25	avoid	avoid	VERB
fnp-3766	357	26	enriching	enrich	VERB
fnp-3766	357	27	for	for	ADP
fnp-3766	357	28	any	any	DET
fnp-3766	357	29	particular	particular	ADJ
fnp-3766	357	30	type	type	NOUN
fnp-3766	357	31	of	of	ADP
fnp-3766	357	32	seeding	seed	VERB
fnp-3766	357	33	activity	activity	NOUN
fnp-3766	357	34	.	.	PUNCT
fnp-3766	358	1	the	the	DET
fnp-3766	358	2	absence	absence	NOUN
fnp-3766	358	3	of	of	ADP
fnp-3766	358	4	tau	tau	PROPN
fnp-3766	358	5	or	or	CCONJ
fnp-3766	358	6	αsyn	αsyn	ADJ
fnp-3766	358	7	pathology	pathology	NOUN
fnp-3766	358	8	in	in	ADP
fnp-3766	358	9	our	our	PRON
fnp-3766	358	10	seeded	seeded	ADJ
fnp-3766	358	11	models	model	NOUN
fnp-3766	358	12	indicates	indicate	VERB
fnp-3766	358	13	that	that	SCONJ
fnp-3766	358	14	the	the	DET
fnp-3766	358	15	type	type	NOUN
fnp-3766	358	16	of	of	ADP
fnp-3766	358	17	aβ	aβ	NOUN
fnp-3766	358	18	deposition	deposition	NOUN
fnp-3766	358	19	we	we	PRON
fnp-3766	358	20	generated	generate	VERB
fnp-3766	358	21	did	do	AUX
fnp-3766	358	22	not	not	PART
fnp-3766	358	23	synergize	synergize	VERB
fnp-3766	358	24	to	to	PART
fnp-3766	358	25	induce	induce	VERB
fnp-3766	358	26	,	,	PUNCT
fnp-3766	358	27	or	or	CCONJ
fnp-3766	358	28	exacerbate	exacerbate	VERB
fnp-3766	358	29	,	,	PUNCT
fnp-3766	358	30	tau	tau	PROPN
fnp-3766	358	31	or	or	CCONJ
fnp-3766	358	32	αsyn	αsyn	ADJ
fnp-3766	358	33	pathology	pathology	NOUN
fnp-3766	358	34	.	.	PUNCT
fnp-3766	359	1	we	we	PRON
fnp-3766	359	2	demonstrated	demonstrate	VERB
fnp-3766	359	3	that	that	SCONJ
fnp-3766	359	4	the	the	DET
fnp-3766	359	5	aβ	aβ	NOUN
fnp-3766	359	6	seeding	seed	VERB
fnp-3766	359	7	activity	activity	NOUN
fnp-3766	359	8	of	of	ADP
fnp-3766	359	9	brain	brain	NOUN
fnp-3766	359	10	lysates	lysate	NOUN
fnp-3766	359	11	from	from	ADP
fnp-3766	359	12	pa	pa	PROPN
fnp-3766	359	13	cases	case	NOUN
fnp-3766	359	14	was	be	AUX
fnp-3766	359	15	similar	similar	ADJ
fnp-3766	359	16	to	to	ADP
fnp-3766	359	17	ad	ad	NOUN
fnp-3766	359	18	and	and	CCONJ
fnp-3766	359	19	ad	ad	NOUN
fnp-3766	359	20	/	/	SYM
fnp-3766	359	21	lbd	lbd	PROPN
fnp-3766	359	22	cases	case	NOUN
fnp-3766	359	23	.	.	PUNCT
fnp-3766	360	1	these	these	DET
fnp-3766	360	2	findings	finding	NOUN
fnp-3766	360	3	agree	agree	VERB
fnp-3766	360	4	with	with	ADP
fnp-3766	360	5	a	a	DET
fnp-3766	360	6	previous	previous	ADJ
fnp-3766	360	7	study	study	NOUN
fnp-3766	360	8	that	that	PRON
fnp-3766	360	9	reported	report	VERB
fnp-3766	360	10	brain	brain	NOUN
fnp-3766	360	11	homogenates	homogenate	NOUN
fnp-3766	360	12	from	from	ADP
fnp-3766	360	13	a	a	DET
fnp-3766	360	14	human	human	ADJ
fnp-3766	360	15	pa	pa	PROPN
fnp-3766	360	16	case	case	NOUN
fnp-3766	360	17	seeded	seed	VERB
fnp-3766	360	18	diffuse	diffuse	NOUN
fnp-3766	360	19	aβ	aβ	ADP
fnp-3766	360	20	deposition	deposition	NOUN
fnp-3766	360	21	in	in	ADP
fnp-3766	360	22	tg2576	tg2576	PROPN
fnp-3766	360	23	app	app	NOUN
fnp-3766	360	24	mice	mouse	NOUN
fnp-3766	360	25	(	(	PUNCT
fnp-3766	360	26	65	65	NUM
fnp-3766	360	27	)	)	PUNCT
fnp-3766	360	28	.	.	PUNCT
fnp-3766	361	1	although	although	SCONJ
fnp-3766	361	2	mice	mouse	NOUN
fnp-3766	361	3	seeded	seed	VERB
fnp-3766	361	4	by	by	ADP
fnp-3766	361	5	pa	pa	PROPN
fnp-3766	361	6	brains	brain	NOUN
fnp-3766	361	7	scored	score	VERB
fnp-3766	361	8	as	as	ADP
fnp-3766	361	9	having	have	VERB
fnp-3766	361	10	less	less	ADJ
fnp-3766	361	11	amyloid	amyloid	NOUN
fnp-3766	361	12	positivity	positivity	NOUN
fnp-3766	361	13	at	at	ADP
fnp-3766	361	14	12	12	NUM
fnp-3766	361	15	months	month	NOUN
fnp-3766	361	16	post	post	ADJ
fnp-3766	361	17	-	-	NOUN
fnp-3766	361	18	injection	injection	NOUN
fnp-3766	361	19	than	than	ADP
fnp-3766	361	20	mice	mouse	NOUN
fnp-3766	361	21	injected	inject	VERB
fnp-3766	361	22	with	with	ADP
fnp-3766	361	23	ad	ad	NOUN
fnp-3766	361	24	brain	brain	NOUN
fnp-3766	361	25	lysates	lysate	NOUN
fnp-3766	361	26	,	,	PUNCT
fnp-3766	361	27	the	the	DET
fnp-3766	361	28	difference	difference	NOUN
fnp-3766	361	29	between	between	ADP
fnp-3766	361	30	pa	pa	PROPN
fnp-3766	361	31	and	and	CCONJ
fnp-3766	361	32	ad	ad	NOUN
fnp-3766	361	33	brain	brain	NOUN
fnp-3766	361	34	seeding	seed	VERB
fnp-3766	361	35	activity	activity	NOUN
fnp-3766	361	36	was	be	AUX
fnp-3766	361	37	less	less	ADV
fnp-3766	361	38	evident	evident	ADJ
fnp-3766	361	39	by	by	ADP
fnp-3766	361	40	18	18	NUM
fnp-3766	361	41	months	month	NOUN
fnp-3766	361	42	post	post	NOUN
fnp-3766	361	43	-	-	NOUN
fnp-3766	361	44	injection	injection	NOUN
fnp-3766	361	45	.	.	PUNCT
fnp-3766	362	1	our	our	PRON
fnp-3766	362	2	study	study	NOUN
fnp-3766	362	3	was	be	AUX
fnp-3766	362	4	not	not	PART
fnp-3766	362	5	powered	power	VERB
fnp-3766	362	6	or	or	CCONJ
fnp-3766	362	7	designed	design	VERB
fnp-3766	362	8	to	to	PART
fnp-3766	362	9	determine	determine	VERB
fnp-3766	362	10	whether	whether	SCONJ
fnp-3766	362	11	homogenates	homogenate	NOUN
fnp-3766	362	12	from	from	ADP
fnp-3766	362	13	ad	ad	NOUN
fnp-3766	362	14	and	and	CCONJ
fnp-3766	362	15	pa	pa	PROPN
fnp-3766	362	16	brains	brain	NOUN
fnp-3766	362	17	have	have	VERB
fnp-3766	362	18	quantitative	quantitative	ADJ
fnp-3766	362	19	differences	difference	NOUN
fnp-3766	362	20	in	in	ADP
fnp-3766	362	21	seeding	seed	VERB
fnp-3766	362	22	activity	activity	NOUN
fnp-3766	362	23	.	.	PUNCT
fnp-3766	363	1	all	all	DET
fnp-3766	363	2	three	three	NUM
fnp-3766	363	3	of	of	ADP
fnp-3766	363	4	the	the	DET
fnp-3766	363	5	pa	pa	PROPN
fnp-3766	363	6	cases	case	NOUN
fnp-3766	363	7	tested	test	VERB
fnp-3766	363	8	were	be	AUX
fnp-3766	363	9	able	able	ADJ
fnp-3766	363	10	to	to	PART
fnp-3766	363	11	seed	seed	VERB
fnp-3766	363	12	amyloid	amyloid	NOUN
fnp-3766	363	13	pathology	pathology	NOUN
fnp-3766	363	14	,	,	PUNCT
fnp-3766	363	15	supporting	support	VERB
fnp-3766	363	16	the	the	DET
fnp-3766	363	17	hypothesis	hypothesis	NOUN
fnp-3766	363	18	that	that	PRON
fnp-3766	363	19	the	the	DET
fnp-3766	363	20	aβ	aβ	PROPN
fnp-3766	363	21	pathology	pathology	NOUN
fnp-3766	363	22	in	in	ADP
fnp-3766	363	23	pa	pa	PROPN
fnp-3766	363	24	is	be	AUX
fnp-3766	363	25	similar	similar	ADJ
fnp-3766	363	26	to	to	ADP
fnp-3766	363	27	ad	ad	NOUN
fnp-3766	363	28	(	(	PUNCT
fnp-3766	363	29	25	25	NUM
fnp-3766	363	30	)	)	PUNCT
fnp-3766	363	31	.	.	PUNCT
fnp-3766	364	1	interestingly	interestingly	ADV
fnp-3766	364	2	,	,	PUNCT
fnp-3766	364	3	several	several	ADJ
fnp-3766	364	4	of	of	ADP
fnp-3766	364	5	the	the	DET
fnp-3766	364	6	brain	brain	NOUN
fnp-3766	364	7	lysates	lysate	NOUN
fnp-3766	364	8	we	we	PRON
fnp-3766	364	9	used	use	VERB
fnp-3766	364	10	were	be	AUX
fnp-3766	364	11	from	from	ADP
fnp-3766	364	12	tissues	tissue	NOUN
fnp-3766	364	13	that	that	PRON
fnp-3766	364	14	exhibited	exhibit	VERB
fnp-3766	364	15	relatively	relatively	ADV
fnp-3766	364	16	high	high	ADJ
fnp-3766	364	17	levels	level	NOUN
fnp-3766	364	18	of	of	ADP
fnp-3766	364	19	caa	caa	PROPN
fnp-3766	364	20	pathology	pathology	NOUN
fnp-3766	364	21	(	(	PUNCT
fnp-3766	364	22	see	see	VERB
fnp-3766	364	23	table	table	NOUN
fnp-3766	364	24	1	1	NUM
fnp-3766	364	25	)	)	PUNCT
fnp-3766	364	26	.	.	PUNCT
fnp-3766	365	1	pa	pa	PROPN
fnp-3766	365	2	3	3	NUM
fnp-3766	365	3	and	and	CCONJ
fnp-3766	365	4	ad	ad	NOUN
fnp-3766	365	5	3	3	NUM
fnp-3766	365	6	were	be	AUX
fnp-3766	365	7	both	both	PRON
fnp-3766	365	8	scored	score	VERB
fnp-3766	365	9	as	as	ADP
fnp-3766	365	10	having	have	VERB
fnp-3766	365	11	the	the	DET
fnp-3766	365	12	highest	high	ADJ
fnp-3766	365	13	levels	level	NOUN
fnp-3766	365	14	of	of	ADP
fnp-3766	365	15	caa	caa	NOUN
fnp-3766	365	16	,	,	PUNCT
fnp-3766	365	17	with	with	ADP
fnp-3766	365	18	significant	significant	ADJ
fnp-3766	365	19	caa	caa	NOUN
fnp-3766	365	20	in	in	ADP
fnp-3766	365	21	ad	ad	NOUN
fnp-3766	365	22	/	/	SYM
fnp-3766	365	23	lbd	lbd	PROPN
fnp-3766	365	24	1	1	NUM
fnp-3766	365	25	and	and	CCONJ
fnp-3766	365	26	2	2	NUM
fnp-3766	365	27	.	.	X
fnp-3766	366	1	in	in	ADP
fnp-3766	366	2	mice	mouse	NOUN
fnp-3766	366	3	injected	inject	VERB
fnp-3766	366	4	with	with	ADP
fnp-3766	366	5	pa	pa	PROPN
fnp-3766	366	6	3	3	NUM
fnp-3766	366	7	,	,	PUNCT
fnp-3766	366	8	we	we	PRON
fnp-3766	366	9	observed	observe	VERB
fnp-3766	366	10	modest	modest	ADJ
fnp-3766	366	11	seeding	seeding	NOUN
fnp-3766	366	12	of	of	ADP
fnp-3766	366	13	parenchymal	parenchymal	ADJ
fnp-3766	366	14	caa	caa	NOUN
fnp-3766	366	15	pathology	pathology	NOUN
fnp-3766	366	16	in	in	ADP
fnp-3766	366	17	the	the	DET
fnp-3766	366	18	host	host	NOUN
fnp-3766	366	19	mice	mouse	NOUN
fnp-3766	366	20	but	but	CCONJ
fnp-3766	366	21	in	in	ADP
fnp-3766	366	22	all	all	DET
fnp-3766	366	23	other	other	ADJ
fnp-3766	366	24	mice	mouse	NOUN
fnp-3766	366	25	the	the	DET
fnp-3766	366	26	only	only	ADJ
fnp-3766	366	27	obvious	obvious	ADJ
fnp-3766	366	28	vascular	vascular	ADJ
fnp-3766	366	29	deposition	deposition	NOUN
fnp-3766	366	30	was	be	AUX
fnp-3766	366	31	meningeal	meningeal	ADJ
fnp-3766	366	32	.	.	PUNCT
fnp-3766	367	1	augmented	augment	VERB
fnp-3766	367	2	caa	caa	PROPN
fnp-3766	367	3	pathology	pathology	NOUN
fnp-3766	367	4	has	have	AUX
fnp-3766	367	5	been	be	AUX
fnp-3766	367	6	observed	observe	VERB
fnp-3766	367	7	in	in	ADP
fnp-3766	367	8	app23	app23	PROPN
fnp-3766	367	9	mice	mouse	NOUN
fnp-3766	367	10	,	,	PUNCT
fnp-3766	367	11	which	which	PRON
fnp-3766	367	12	develop	develop	VERB
fnp-3766	367	13	caa	caa	NOUN
fnp-3766	367	14	,	,	PUNCT
fnp-3766	367	15	by	by	ADP
fnp-3766	367	16	intraperitoneal	intraperitoneal	ADJ
fnp-3766	367	17	injection	injection	NOUN
fnp-3766	367	18	of	of	ADP
fnp-3766	367	19	app23	app23	PROPN
fnp-3766	367	20	lysates	lysate	NOUN
fnp-3766	367	21	(	(	PUNCT
fnp-3766	367	22	66	66	NUM
fnp-3766	367	23	)	)	PUNCT
fnp-3766	367	24	.	.	PUNCT
fnp-3766	368	1	caa	caa	PROPN
fnp-3766	368	2	pathology	pathology	PROPN
fnp-3766	368	3	was	be	AUX
fnp-3766	368	4	also	also	ADV
fnp-3766	368	5	induced	induce	VERB
fnp-3766	368	6	in	in	ADP
fnp-3766	368	7	crnd8	crnd8	NOUN
fnp-3766	368	8	mice	mouse	NOUN
fnp-3766	368	9	by	by	ADP
fnp-3766	368	10	injection	injection	NOUN
fnp-3766	368	11	of	of	ADP
fnp-3766	368	12	synthetic	synthetic	ADJ
fnp-3766	368	13	aβ42	aβ42	PROPN
fnp-3766	368	14	oligomers	oligomer	NOUN
fnp-3766	368	15	,	,	PUNCT
fnp-3766	368	16	generated	generate	VERB
fnp-3766	368	17	in	in	ADP
fnp-3766	368	18	the	the	DET
fnp-3766	368	19	presence	presence	NOUN
fnp-3766	368	20	of	of	ADP
fnp-3766	368	21	anionic	anionic	ADJ
fnp-3766	368	22	micelles	micelle	NOUN
fnp-3766	368	23	composed	compose	VERB
fnp-3766	368	24	of	of	ADP
fnp-3766	368	25	fatty	fatty	ADJ
fnp-3766	368	26	acids	acid	NOUN
fnp-3766	368	27	(	(	PUNCT
fnp-3766	368	28	67	67	NUM
fnp-3766	368	29	)	)	PUNCT
fnp-3766	368	30	.	.	PUNCT
fnp-3766	369	1	recent	recent	ADJ
fnp-3766	369	2	studies	study	NOUN
fnp-3766	369	3	have	have	AUX
fnp-3766	369	4	documented	document	VERB
fnp-3766	369	5	early	early	ADJ
fnp-3766	369	6	onset	onset	NOUN
fnp-3766	369	7	cerebrovascular	cerebrovascular	ADJ
fnp-3766	369	8	aβ	aβ	DET
fnp-3766	369	9	pathology	pathology	NOUN
fnp-3766	369	10	in	in	ADP
fnp-3766	369	11	individuals	individual	NOUN
fnp-3766	369	12	receiving	receive	VERB
fnp-3766	369	13	dura	dura	NOUN
fnp-3766	369	14	mater	mater	NOUN
fnp-3766	369	15	transplants	transplant	NOUN
fnp-3766	369	16	and	and	CCONJ
fnp-3766	369	17	cadaveric	cadaveric	ADJ
fnp-3766	369	18	pituitary	pituitary	NOUN
fnp-3766	369	19	-	-	PUNCT
fnp-3766	369	20	derived	derive	VERB
fnp-3766	369	21	growth	growth	NOUN
fnp-3766	369	22	hormone	hormone	NOUN
fnp-3766	369	23	,	,	PUNCT
fnp-3766	369	24	suggesting	suggest	VERB
fnp-3766	369	25	that	that	DET
fnp-3766	369	26	caa	caa	NOUN
fnp-3766	369	27	may	may	AUX
fnp-3766	369	28	be	be	AUX
fnp-3766	369	29	transmitted	transmit	VERB
fnp-3766	369	30	iatrogenically	iatrogenically	ADV
fnp-3766	369	31	(	(	PUNCT
fnp-3766	369	32	68	68	NUM
fnp-3766	369	33	,	,	PUNCT
fnp-3766	369	34	69	69	NUM
fnp-3766	369	35	)	)	PUNCT
fnp-3766	369	36	.	.	PUNCT
fnp-3766	370	1	collectively	collectively	ADV
fnp-3766	370	2	,	,	PUNCT
fnp-3766	370	3	these	these	DET
fnp-3766	370	4	results	result	NOUN
fnp-3766	370	5	suggest	suggest	VERB
fnp-3766	370	6	that	that	SCONJ
fnp-3766	370	7	caa	caa	NOUN
fnp-3766	370	8	could	could	AUX
fnp-3766	370	9	be	be	AUX
fnp-3766	370	10	a	a	DET
fnp-3766	370	11	distinct	distinct	ADJ
fnp-3766	370	12	conformer	conformer	NOUN
fnp-3766	370	13	of	of	ADP
fnp-3766	370	14	aβ	aβ	PRON
fnp-3766	370	15	that	that	PRON
fnp-3766	370	16	may	may	AUX
fnp-3766	370	17	be	be	AUX
fnp-3766	370	18	independently	independently	ADV
fnp-3766	370	19	propagated	propagate	VERB
fnp-3766	370	20	.	.	PUNCT
fnp-3766	371	1	not	not	PART
fnp-3766	371	2	all	all	PRON
fnp-3766	371	3	aβ	aβ	DET
fnp-3766	371	4	conformers	conformer	NOUN
fnp-3766	371	5	seeded	seed	VERB
fnp-3766	371	6	as	as	ADV
fnp-3766	371	7	proficiently	proficiently	ADV
fnp-3766	371	8	as	as	ADP
fnp-3766	371	9	vascular	vascular	ADJ
fnp-3766	371	10	aβ	aβ	NOUN
fnp-3766	371	11	.	.	NOUN
fnp-3766	371	12	tissues	tissue	NOUN
fnp-3766	371	13	from	from	ADP
fnp-3766	371	14	ad	ad	NOUN
fnp-3766	371	15	and	and	CCONJ
fnp-3766	371	16	ad	ad	NOUN
fnp-3766	371	17	/	/	SYM
fnp-3766	371	18	lbd	lbd	NOUN
fnp-3766	371	19	brains	brain	NOUN
fnp-3766	371	20	that	that	PRON
fnp-3766	371	21	were	be	AUX
fnp-3766	371	22	used	use	VERB
fnp-3766	371	23	to	to	PART
fnp-3766	371	24	prepare	prepare	VERB
fnp-3766	371	25	these	these	DET
fnp-3766	371	26	lysates	lysate	NOUN
fnp-3766	371	27	contained	contain	VERB
fnp-3766	371	28	both	both	CCONJ
fnp-3766	371	29	diffuse	diffuse	NOUN
fnp-3766	371	30	and	and	CCONJ
fnp-3766	371	31	compact	compact	ADJ
fnp-3766	372	1	aβ	aβ	DET
fnp-3766	372	2	deposits	deposit	NOUN
fnp-3766	372	3	,	,	PUNCT
fnp-3766	372	4	with	with	ADP
fnp-3766	372	5	significant	significant	ADJ
fnp-3766	372	6	levels	level	NOUN
fnp-3766	372	7	of	of	ADP
fnp-3766	372	8	formic	formic	ADJ
fnp-3766	372	9	acid	acid	PROPN
fnp-3766	372	10	extractable	extractable	ADJ
fnp-3766	372	11	aβ	aβ	NOUN
fnp-3766	372	12	.	.	PUNCT
fnp-3766	373	1	yet	yet	ADV
fnp-3766	373	2	,	,	PUNCT
fnp-3766	373	3	even	even	ADV
fnp-3766	373	4	in	in	ADP
fnp-3766	373	5	mice	mouse	NOUN
fnp-3766	373	6	aged	age	VERB
fnp-3766	373	7	to	to	ADP
fnp-3766	373	8	18	18	NUM
fnp-3766	373	9	months	month	NOUN
fnp-3766	373	10	of	of	ADP
fnp-3766	373	11	age	age	NOUN
fnp-3766	373	12	,	,	PUNCT
fnp-3766	373	13	diffuse	diffuse	VERB
fnp-3766	373	14	aβ	aβ	NOUN
fnp-3766	373	15	deposits	deposit	NOUN
fnp-3766	373	16	were	be	AUX
fnp-3766	373	17	the	the	DET
fnp-3766	373	18	dominant	dominant	ADJ
fnp-3766	373	19	form	form	NOUN
fnp-3766	373	20	of	of	ADP
fnp-3766	373	21	pathology	pathology	NOUN
fnp-3766	373	22	.	.	PUNCT
fnp-3766	374	1	these	these	DET
fnp-3766	374	2	results	result	NOUN
fnp-3766	374	3	mirror	mirror	VERB
fnp-3766	374	4	similar	similar	ADJ
fnp-3766	374	5	studies	study	NOUN
fnp-3766	374	6	in	in	ADP
fnp-3766	374	7	which	which	PRON
fnp-3766	374	8	injection	injection	NOUN
fnp-3766	374	9	of	of	ADP
fnp-3766	374	10	human	human	ADJ
fnp-3766	374	11	brain	brain	NOUN
fnp-3766	374	12	homogenates	homogenate	NOUN
fnp-3766	374	13	resulted	result	VERB
fnp-3766	374	14	in	in	ADP
fnp-3766	374	15	induction	induction	NOUN
fnp-3766	374	16	of	of	ADP
fnp-3766	374	17	diffuse	diffuse	NOUN
fnp-3766	374	18	aβ	aβ	DET
fnp-3766	374	19	pathology	pathology	NOUN
fnp-3766	374	20	,	,	PUNCT
fnp-3766	374	21	with	with	ADP
fnp-3766	374	22	relatively	relatively	ADV
fnp-3766	374	23	few	few	ADJ
fnp-3766	374	24	thio	thio	NOUN
fnp-3766	374	25	-	-	PUNCT
fnp-3766	374	26	s	s	NOUN
fnp-3766	374	27	or	or	CCONJ
fnp-3766	374	28	congophilic	congophilic	ADJ
fnp-3766	374	29	compact	compact	ADJ
fnp-3766	374	30	deposits	deposit	NOUN
fnp-3766	374	31	(	(	PUNCT
fnp-3766	374	32	49	49	NUM
fnp-3766	374	33	,	,	PUNCT
fnp-3766	374	34	65	65	NUM
fnp-3766	374	35	,	,	PUNCT
fnp-3766	374	36	70	70	NUM
fnp-3766	374	37	,	,	PUNCT
fnp-3766	374	38	71	71	NUM
fnp-3766	374	39	)	)	PUNCT
fnp-3766	374	40	.	.	PUNCT
fnp-3766	375	1	the	the	DET
fnp-3766	375	2	lack	lack	NOUN
fnp-3766	375	3	of	of	ADP
fnp-3766	375	4	conversion	conversion	NOUN
fnp-3766	375	5	of	of	ADP
fnp-3766	375	6	the	the	DET
fnp-3766	375	7	diffuse	diffuse	NOUN
fnp-3766	375	8	deposits	deposit	NOUN
fnp-3766	375	9	to	to	PART
fnp-3766	375	10	cored	core	VERB
fnp-3766	375	11	plaques	plaque	NOUN
fnp-3766	375	12	indicates	indicate	VERB
fnp-3766	375	13	that	that	SCONJ
fnp-3766	375	14	these	these	DET
fnp-3766	375	15	types	type	NOUN
fnp-3766	375	16	of	of	ADP
fnp-3766	375	17	amyloid	amyloid	NOUN
fnp-3766	375	18	deposition	deposition	NOUN
fnp-3766	375	19	are	be	AUX
fnp-3766	375	20	not	not	PART
fnp-3766	375	21	freely	freely	ADV
fnp-3766	375	22	interchangeable	interchangeable	ADJ
fnp-3766	375	23	,	,	PUNCT
fnp-3766	375	24	supporting	support	VERB
fnp-3766	375	25	the	the	DET
fnp-3766	375	26	idea	idea	NOUN
fnp-3766	375	27	that	that	SCONJ
fnp-3766	375	28	each	each	DET
fnp-3766	375	29	type	type	NOUN
fnp-3766	375	30	of	of	ADP
fnp-3766	375	31	aβ	aβ	DET
fnp-3766	375	32	pathology	pathology	NOUN
fnp-3766	375	33	arises	arise	VERB
fnp-3766	375	34	from	from	ADP
fnp-3766	375	35	different	different	ADJ
fnp-3766	375	36	amyloid	amyloid	NOUN
fnp-3766	375	37	strains	strain	VERB
fnp-3766	375	38	with	with	ADP
fnp-3766	375	39	distinct	distinct	ADJ
fnp-3766	375	40	seeding	seeding	NOUN
fnp-3766	375	41	capabilities	capability	NOUN
fnp-3766	375	42	.	.	PUNCT
fnp-3766	376	1	this	this	DET
fnp-3766	376	2	conclusion	conclusion	NOUN
fnp-3766	376	3	is	be	AUX
fnp-3766	376	4	also	also	ADV
fnp-3766	376	5	supported	support	VERB
fnp-3766	376	6	by	by	ADP
fnp-3766	376	7	our	our	PRON
fnp-3766	376	8	studies	study	NOUN
fnp-3766	376	9	of	of	ADP
fnp-3766	376	10	aβ	aβ	NOUN
fnp-3766	376	11	seeding	seed	VERB
fnp-3766	376	12	in	in	ADP
fnp-3766	376	13	which	which	PRON
fnp-3766	376	14	transgenic	transgenic	NOUN
fnp-3766	376	15	mice	mouse	NOUN
fnp-3766	376	16	were	be	AUX
fnp-3766	376	17	used	use	VERB
fnp-3766	376	18	as	as	ADP
fnp-3766	376	19	the	the	DET
fnp-3766	376	20	seed	seed	NOUN
fnp-3766	376	21	source	source	NOUN
fnp-3766	376	22	.	.	PUNCT
fnp-3766	377	1	newborn	newborn	ADJ
fnp-3766	377	2	prp.appsi	prp.appsi	PROPN
fnp-3766	377	3	mice	mouse	NOUN
fnp-3766	377	4	injected	inject	VERB
fnp-3766	377	5	with	with	ADP
fnp-3766	377	6	transgenic	transgenic	NOUN
fnp-3766	377	7	mouse	mouse	NOUN
fnp-3766	377	8	brain	brain	NOUN
fnp-3766	377	9	homogenates	homogenate	NOUN
fnp-3766	377	10	prepared	prepare	VERB
fnp-3766	377	11	from	from	ADP
fnp-3766	377	12	mice	mouse	NOUN
fnp-3766	377	13	that	that	PRON
fnp-3766	377	14	exhibit	exhibit	VERB
fnp-3766	377	15	high	high	ADJ
fnp-3766	377	16	levels	level	NOUN
fnp-3766	377	17	of	of	ADP
fnp-3766	377	18	diffuse	diffuse	NOUN
fnp-3766	377	19	aβ	aβ	DET
fnp-3766	377	20	pathology	pathology	NOUN
fnp-3766	377	21	produced	produce	VERB
fnp-3766	377	22	a	a	DET
fnp-3766	377	23	robust	robust	ADJ
fnp-3766	377	24	induction	induction	NOUN
fnp-3766	377	25	of	of	ADP
fnp-3766	377	26	diffuse	diffuse	NOUN
fnp-3766	377	27	aβ	aβ	ADP
fnp-3766	377	28	deposition	deposition	NOUN
fnp-3766	377	29	by	by	ADP
fnp-3766	377	30	12	12	NUM
fnp-3766	377	31	months	month	NOUN
fnp-3766	377	32	post	post	NOUN
fnp-3766	377	33	-	-	NOUN
fnp-3766	377	34	injection	injection	NOUN
fnp-3766	377	35	.	.	PUNCT
fnp-3766	378	1	by	by	ADP
fnp-3766	378	2	contrast	contrast	NOUN
fnp-3766	378	3	,	,	PUNCT
fnp-3766	378	4	brain	brain	NOUN
fnp-3766	378	5	homogenates	homogenate	NOUN
fnp-3766	378	6	prepared	prepare	VERB
fnp-3766	378	7	from	from	ADP
fnp-3766	378	8	mice	mouse	NOUN
fnp-3766	378	9	that	that	PRON
fnp-3766	378	10	predominantly	predominantly	ADV
fnp-3766	378	11	produce	produce	VERB
fnp-3766	378	12	cored	core	VERB
fnp-3766	378	13	,	,	PUNCT
fnp-3766	378	14	thio	thio	NOUN
fnp-3766	378	15	-	-	PUNCT
fnp-3766	378	16	s	s	NOUN
fnp-3766	378	17	positive	positive	ADJ
fnp-3766	378	18	,	,	PUNCT
fnp-3766	378	19	aβ	aβ	DET
fnp-3766	378	20	deposits	deposit	NOUN
fnp-3766	378	21	induced	induce	VERB
fnp-3766	378	22	minimal	minimal	ADJ
fnp-3766	378	23	aβ	aβ	ADP
fnp-3766	378	24	deposition	deposition	NOUN
fnp-3766	378	25	by	by	ADP
fnp-3766	378	26	12	12	NUM
fnp-3766	378	27	months	month	NOUN
fnp-3766	378	28	.	.	PUNCT
fnp-3766	379	1	these	these	DET
fnp-3766	379	2	results	result	NOUN
fnp-3766	379	3	are	be	AUX
fnp-3766	379	4	consistent	consistent	ADJ
fnp-3766	379	5	with	with	ADP
fnp-3766	379	6	previous	previous	ADJ
fnp-3766	379	7	studies	study	NOUN
fnp-3766	379	8	with	with	ADP
fnp-3766	379	9	app	app	PROPN
fnp-3766	379	10	/	/	SYM
fnp-3766	379	11	ps1	ps1	PROPN
fnp-3766	379	12	and	and	CCONJ
fnp-3766	379	13	app23	app23	PROPN
fnp-3766	379	14	mice	mouse	NOUN
fnp-3766	379	15	.	.	PUNCT
fnp-3766	380	1	injection	injection	NOUN
fnp-3766	380	2	of	of	ADP
fnp-3766	380	3	appps1	appps1	PROPN
fnp-3766	380	4	mice	mouse	NOUN
fnp-3766	380	5	that	that	PRON
fnp-3766	380	6	typically	typically	ADV
fnp-3766	380	7	develop	develop	VERB
fnp-3766	380	8	compact	compact	ADJ
fnp-3766	380	9	,	,	PUNCT
fnp-3766	380	10	punctate	punctate	NOUN
fnp-3766	380	11	plaques	plaque	NOUN
fnp-3766	380	12	,	,	PUNCT
fnp-3766	380	13	with	with	ADP
fnp-3766	380	14	app23	app23	PROPN
fnp-3766	380	15	seeds	seed	NOUN
fnp-3766	380	16	results	result	NOUN
fnp-3766	380	17	in	in	ADP
fnp-3766	380	18	a	a	DET
fnp-3766	380	19	mixture	mixture	NOUN
fnp-3766	380	20	of	of	ADP
fnp-3766	380	21	diffuse	diffuse	NOUN
fnp-3766	380	22	,	,	PUNCT
fnp-3766	380	23	filamentous	filamentous	ADJ
fnp-3766	380	24	aβ	aβ	NOUN
fnp-3766	380	25	as	as	ADV
fnp-3766	380	26	well	well	ADV
fnp-3766	380	27	as	as	ADP
fnp-3766	380	28	compact	compact	ADJ
fnp-3766	380	29	plaques	plaque	NOUN
fnp-3766	380	30	(	(	PUNCT
fnp-3766	380	31	42	42	NUM
fnp-3766	380	32	,	,	PUNCT
fnp-3766	380	33	72	72	NUM
fnp-3766	380	34	)	)	PUNCT
fnp-3766	380	35	.	.	PUNCT
fnp-3766	381	1	injection	injection	NOUN
fnp-3766	381	2	of	of	ADP
fnp-3766	381	3	app23	app23	PROPN
fnp-3766	381	4	mice	mouse	NOUN
fnp-3766	381	5	that	that	PRON
fnp-3766	381	6	typically	typically	ADV
fnp-3766	381	7	develop	develop	VERB
fnp-3766	381	8	mixed	mixed	ADJ
fnp-3766	381	9	pathology	pathology	NOUN
fnp-3766	381	10	,	,	PUNCT
fnp-3766	381	11	both	both	PRON
fnp-3766	381	12	cored	core	VERB
fnp-3766	381	13	and	and	CCONJ
fnp-3766	381	14	diffuse	diffuse	VERB
fnp-3766	381	15	plaques	plaque	NOUN
fnp-3766	381	16	,	,	PUNCT
fnp-3766	381	17	with	with	ADP
fnp-3766	381	18	appps1	appps1	PROPN
fnp-3766	381	19	homogenate	homogenate	NOUN
fnp-3766	381	20	results	result	NOUN
fnp-3766	381	21	in	in	ADP
fnp-3766	381	22	plaques	plaque	NOUN
fnp-3766	381	23	that	that	PRON
fnp-3766	381	24	are	be	AUX
fnp-3766	381	25	more	more	ADV
fnp-3766	381	26	diffuse	diffuse	ADJ
fnp-3766	381	27	than	than	ADP
fnp-3766	381	28	the	the	DET
fnp-3766	381	29	punctate	punctate	NOUN
fnp-3766	381	30	deposits	deposit	NOUN
fnp-3766	381	31	seen	see	VERB
fnp-3766	381	32	in	in	ADP
fnp-3766	381	33	appps1	appps1	NOUN
fnp-3766	381	34	mice	mouse	NOUN
fnp-3766	381	35	injected	inject	VERB
fnp-3766	381	36	with	with	ADP
fnp-3766	381	37	appps1	appps1	PROPN
fnp-3766	381	38	homogenate	homogenate	NOUN
fnp-3766	381	39	(	(	PUNCT
fnp-3766	381	40	42	42	NUM
fnp-3766	381	41	,	,	PUNCT
fnp-3766	381	42	72	72	NUM
fnp-3766	381	43	)	)	PUNCT
fnp-3766	381	44	.	.	PUNCT
fnp-3766	382	1	thus	thus	ADV
fnp-3766	382	2	,	,	PUNCT
fnp-3766	382	3	although	although	SCONJ
fnp-3766	382	4	it	it	PRON
fnp-3766	382	5	is	be	AUX
fnp-3766	382	6	possible	possible	ADJ
fnp-3766	382	7	to	to	PART
fnp-3766	382	8	seed	seed	VERB
fnp-3766	382	9	cored	core	VERB
fnp-3766	382	10	deposits	deposit	NOUN
fnp-3766	382	11	in	in	ADP
fnp-3766	382	12	app	app	NOUN
fnp-3766	382	13	mice	mouse	NOUN
fnp-3766	382	14	(	(	PUNCT
fnp-3766	382	15	42	42	NUM
fnp-3766	382	16	,	,	PUNCT
fnp-3766	382	17	55	55	NUM
fnp-3766	382	18	,	,	PUNCT
fnp-3766	382	19	73	73	NUM
fnp-3766	382	20	-	-	SYM
fnp-3766	382	21	75	75	NUM
fnp-3766	382	22	)	)	PUNCT
fnp-3766	382	23	,	,	PUNCT
fnp-3766	382	24	it	it	PRON
fnp-3766	382	25	appears	appear	VERB
fnp-3766	382	26	that	that	SCONJ
fnp-3766	382	27	diffuse	diffuse	NOUN
fnp-3766	382	28	aβ	aβ	PRON
fnp-3766	382	29	pathology	pathology	NOUN
fnp-3766	382	30	is	be	AUX
fnp-3766	382	31	more	more	ADV
fnp-3766	382	32	easily	easily	ADV
fnp-3766	382	33	seeded	seed	VERB
fnp-3766	382	34	.	.	PUNCT
fnp-3766	383	1	together	together	ADV
fnp-3766	383	2	these	these	DET
fnp-3766	383	3	results	result	NOUN
fnp-3766	383	4	suggest	suggest	VERB
fnp-3766	383	5	that	that	SCONJ
fnp-3766	383	6	aβ	aβ	DET
fnp-3766	383	7	plaques	plaque	NOUN
fnp-3766	383	8	differ	differ	VERB
fnp-3766	383	9	in	in	ADP
fnp-3766	383	10	their	their	PRON
fnp-3766	383	11	morphology	morphology	NOUN
fnp-3766	383	12	,	,	PUNCT
fnp-3766	383	13	seeding	seed	VERB
fnp-3766	383	14	ability	ability	NOUN
fnp-3766	383	15	,	,	PUNCT
fnp-3766	383	16	and	and	CCONJ
fnp-3766	383	17	impact	impact	NOUN
fnp-3766	383	18	on	on	ADP
fnp-3766	383	19	cognitive	cognitive	ADJ
fnp-3766	383	20	function	function	NOUN
fnp-3766	383	21	.	.	PUNCT
fnp-3766	384	1	current	current	ADJ
fnp-3766	384	2	amyloid	amyloid	NOUN
fnp-3766	384	3	therapies	therapy	NOUN
fnp-3766	384	4	aim	aim	VERB
fnp-3766	384	5	to	to	PART
fnp-3766	384	6	reduce	reduce	VERB
fnp-3766	384	7	amyloid	amyloid	NOUN
fnp-3766	384	8	deposition	deposition	NOUN
fnp-3766	384	9	without	without	ADP
fnp-3766	384	10	much	much	ADJ
fnp-3766	384	11	consideration	consideration	NOUN
fnp-3766	384	12	of	of	ADP
fnp-3766	384	13	the	the	DET
fnp-3766	384	14	type	type	NOUN
fnp-3766	384	15	of	of	ADP
fnp-3766	384	16	plaque	plaque	NOUN
fnp-3766	384	17	that	that	PRON
fnp-3766	384	18	is	be	AUX
fnp-3766	384	19	being	be	AUX
fnp-3766	384	20	targeted	target	VERB
fnp-3766	384	21	.	.	PUNCT
fnp-3766	385	1	reduction	reduction	NOUN
fnp-3766	385	2	of	of	ADP
fnp-3766	385	3	diffuse	diffuse	ADJ
fnp-3766	385	4	amyloid	amyloid	NOUN
fnp-3766	385	5	may	may	AUX
fnp-3766	385	6	at	at	AUX
fnp-3766	385	7	first	first	ADV
fnp-3766	385	8	appear	appear	VERB
fnp-3766	385	9	to	to	PART
fnp-3766	385	10	be	be	AUX
fnp-3766	385	11	beneficial	beneficial	ADJ
fnp-3766	385	12	,	,	PUNCT
fnp-3766	385	13	since	since	SCONJ
fnp-3766	385	14	it	it	PRON
fnp-3766	385	15	appears	appear	VERB
fnp-3766	385	16	to	to	PART
fnp-3766	385	17	be	be	AUX
fnp-3766	385	18	the	the	DET
fnp-3766	385	19	dominate	dominate	NOUN
fnp-3766	385	20	seeding	seed	VERB
fnp-3766	385	21	strain	strain	NOUN
fnp-3766	385	22	,	,	PUNCT
fnp-3766	385	23	however	however	ADV
fnp-3766	385	24	,	,	PUNCT
fnp-3766	385	25	it	it	PRON
fnp-3766	385	26	may	may	AUX
fnp-3766	385	27	not	not	PART
fnp-3766	385	28	be	be	AUX
fnp-3766	385	29	the	the	DET
fnp-3766	385	30	most	most	ADV
fnp-3766	385	31	pathological	pathological	ADJ
fnp-3766	385	32	strain	strain	NOUN
fnp-3766	385	33	.	.	PUNCT
fnp-3766	386	1	cognitive	cognitive	ADJ
fnp-3766	386	2	behavior	behavior	NOUN
fnp-3766	386	3	studies	study	NOUN
fnp-3766	386	4	of	of	ADP
fnp-3766	386	5	the	the	DET
fnp-3766	386	6	seeded	seeded	ADJ
fnp-3766	386	7	appsi	appsi	PROPN
fnp-3766	386	8	mice	mouse	NOUN
fnp-3766	386	9	reported	report	VERB
fnp-3766	386	10	here	here	ADV
fnp-3766	386	11	,	,	PUNCT
fnp-3766	386	12	and	and	CCONJ
fnp-3766	386	13	of	of	ADP
fnp-3766	386	14	a	a	DET
fnp-3766	386	15	non	non	ADJ
fnp-3766	386	16	-	-	ADJ
fnp-3766	386	17	seeded	seeded	ADJ
fnp-3766	386	18	bri	bri	NOUN
fnp-3766	386	19	-	-	PUNCT
fnp-3766	386	20	aβ42	aβ42	PROPN
fnp-3766	386	21	model	model	NOUN
fnp-3766	386	22	that	that	PRON
fnp-3766	386	23	also	also	ADV
fnp-3766	386	24	shows	show	VERB
fnp-3766	386	25	primarily	primarily	ADV
fnp-3766	386	26	diffuse	diffuse	VERB
fnp-3766	386	27	aβ	aβ	DET
fnp-3766	386	28	pathology	pathology	NOUN
fnp-3766	386	29	(	(	PUNCT
fnp-3766	386	30	76	76	NUM
fnp-3766	386	31	)	)	PUNCT
fnp-3766	386	32	,	,	PUNCT
fnp-3766	386	33	failed	fail	VERB
fnp-3766	386	34	to	to	PART
fnp-3766	386	35	associate	associate	VERB
fnp-3766	386	36	diffuse	diffuse	NOUN
fnp-3766	386	37	amyloid	amyloid	NOUN
fnp-3766	386	38	with	with	ADP
fnp-3766	386	39	reduced	reduce	VERB
fnp-3766	386	40	performance	performance	NOUN
fnp-3766	386	41	in	in	ADP
fnp-3766	386	42	a	a	DET
fnp-3766	386	43	fear	fear	NOUN
fnp-3766	386	44	-	-	PUNCT
fnp-3766	386	45	conditioning	conditioning	NOUN
fnp-3766	386	46	memory	memory	NOUN
fnp-3766	386	47	task	task	NOUN
fnp-3766	386	48	.	.	PUNCT
fnp-3766	387	1	if	if	SCONJ
fnp-3766	387	2	diffuse	diffuse	NOUN
fnp-3766	387	3	aβ	aβ	PRON
fnp-3766	387	4	pathology	pathology	NOUN
fnp-3766	387	5	is	be	AUX
fnp-3766	387	6	less	less	ADV
fnp-3766	387	7	damaging	damaging	ADJ
fnp-3766	387	8	,	,	PUNCT
fnp-3766	387	9	then	then	ADV
fnp-3766	387	10	therapies	therapie	VERB
fnp-3766	387	11	that	that	PRON
fnp-3766	387	12	only	only	ADV
fnp-3766	387	13	reduce	reduce	VERB
fnp-3766	387	14	this	this	DET
fnp-3766	387	15	pathology	pathology	NOUN
fnp-3766	387	16	may	may	AUX
fnp-3766	387	17	not	not	PART
fnp-3766	387	18	produce	produce	VERB
fnp-3766	387	19	therapeutic	therapeutic	ADJ
fnp-3766	387	20	benefit	benefit	NOUN
fnp-3766	387	21	in	in	ADP
fnp-3766	387	22	ad	ad	NOUN
fnp-3766	387	23	.	.	PUNCT
fnp-3766	388	1	conclusions	conclusion	NOUN
fnp-3766	388	2	in	in	ADP
fnp-3766	388	3	conclusion	conclusion	NOUN
fnp-3766	388	4	,	,	PUNCT
fnp-3766	388	5	we	we	PRON
fnp-3766	388	6	assessed	assess	VERB
fnp-3766	388	7	the	the	DET
fnp-3766	388	8	type	type	NOUN
fnp-3766	388	9	of	of	ADP
fnp-3766	388	10	pathology	pathology	NOUN
fnp-3766	388	11	induced	induce	VERB
fnp-3766	388	12	when	when	SCONJ
fnp-3766	388	13	neonatal	neonatal	ADJ
fnp-3766	388	14	app	app	NOUN
fnp-3766	388	15	transgenic	transgenic	NOUN
fnp-3766	388	16	mice	mouse	NOUN
fnp-3766	388	17	were	be	AUX
fnp-3766	388	18	injected	inject	VERB
fnp-3766	388	19	with	with	ADP
fnp-3766	388	20	brain	brain	NOUN
fnp-3766	388	21	lysates	lysate	NOUN
fnp-3766	388	22	prepared	prepare	VERB
fnp-3766	388	23	from	from	ADP
fnp-3766	388	24	ad	ad	NOUN
fnp-3766	388	25	,	,	PUNCT
fnp-3766	388	26	ad	ad	NOUN
fnp-3766	388	27	/	/	SYM
fnp-3766	388	28	lbd	lbd	PROPN
fnp-3766	388	29	,	,	PUNCT
fnp-3766	388	30	and	and	CCONJ
fnp-3766	388	31	pa	pa	PROPN
fnp-3766	388	32	brains	brain	NOUN
fnp-3766	388	33	,	,	PUNCT
fnp-3766	388	34	finding	find	VERB
fnp-3766	388	35	robust	robust	ADJ
fnp-3766	388	36	and	and	CCONJ
fnp-3766	388	37	widespread	widespread	ADJ
fnp-3766	388	38	induction	induction	NOUN
fnp-3766	388	39	of	of	ADP
fnp-3766	388	40	aβ	aβ	DET
fnp-3766	388	41	pathology	pathology	NOUN
fnp-3766	388	42	.	.	PUNCT
fnp-3766	389	1	the	the	DET
fnp-3766	389	2	induced	induced	ADJ
fnp-3766	389	3	aβ	aβ	PRON
fnp-3766	389	4	pathology	pathology	NOUN
fnp-3766	389	5	was	be	AUX
fnp-3766	389	6	diffuse	diffuse	ADJ
fnp-3766	389	7	,	,	PUNCT
fnp-3766	389	8	which	which	PRON
fnp-3766	389	9	has	have	AUX
fnp-3766	389	10	been	be	AUX
fnp-3766	389	11	reported	report	VERB
fnp-3766	389	12	in	in	ADP
fnp-3766	389	13	other	other	ADJ
fnp-3766	389	14	seeding	seed	VERB
fnp-3766	389	15	studies	study	NOUN
fnp-3766	389	16	where	where	SCONJ
fnp-3766	389	17	adult	adult	NOUN
fnp-3766	389	18	animals	animal	NOUN
fnp-3766	389	19	were	be	AUX
fnp-3766	389	20	the	the	DET
fnp-3766	389	21	recipients	recipient	NOUN
fnp-3766	389	22	of	of	ADP
fnp-3766	389	23	injections	injection	NOUN
fnp-3766	389	24	(	(	PUNCT
fnp-3766	389	25	13	13	NUM
fnp-3766	389	26	)	)	PUNCT
fnp-3766	389	27	.	.	PUNCT
fnp-3766	390	1	our	our	PRON
fnp-3766	390	2	results	result	NOUN
fnp-3766	390	3	are	be	AUX
fnp-3766	390	4	consistent	consistent	ADJ
fnp-3766	390	5	with	with	ADP
fnp-3766	390	6	earlier	early	ADJ
fnp-3766	390	7	reports	report	NOUN
fnp-3766	390	8	in	in	ADP
fnp-3766	390	9	finding	find	VERB
fnp-3766	390	10	that	that	PRON
fnp-3766	390	11	diffuse	diffuse	NOUN
fnp-3766	390	12	aβ	aβ	NOUN
fnp-3766	390	13	is	be	AUX
fnp-3766	390	14	easily	easily	ADV
fnp-3766	390	15	seeded	seed	VERB
fnp-3766	390	16	by	by	ADP
fnp-3766	390	17	crude	crude	ADJ
fnp-3766	390	18	homogenates	homogenate	NOUN
fnp-3766	390	19	of	of	ADP
fnp-3766	390	20	human	human	ADJ
fnp-3766	390	21	brain	brain	NOUN
fnp-3766	390	22	.	.	PUNCT
fnp-3766	391	1	the	the	DET
fnp-3766	391	2	diffuse	diffuse	NOUN
fnp-3766	391	3	aβ	aβ	DET
fnp-3766	391	4	pathology	pathology	NOUN
fnp-3766	391	5	induced	induce	VERB
fnp-3766	391	6	in	in	ADP
fnp-3766	391	7	these	these	DET
fnp-3766	391	8	models	model	NOUN
fnp-3766	391	9	was	be	AUX
fnp-3766	391	10	not	not	PART
fnp-3766	391	11	accompanied	accompany	VERB
fnp-3766	391	12	by	by	ADP
fnp-3766	391	13	secondary	secondary	ADJ
fnp-3766	391	14	tau	tau	PROPN
fnp-3766	391	15	or	or	CCONJ
fnp-3766	391	16	αsyn	αsyn	ADJ
fnp-3766	391	17	pathology	pathology	NOUN
fnp-3766	391	18	in	in	ADP
fnp-3766	391	19	bigenic	bigenic	ADJ
fnp-3766	391	20	mice	mouse	NOUN
fnp-3766	391	21	co	co	VERB
fnp-3766	391	22	-	-	VERB
fnp-3766	391	23	expressing	express	VERB
fnp-3766	391	24	app	app	PROPN
fnp-3766	391	25	/	/	SYM
fnp-3766	391	26	tau	tau	PROPN
fnp-3766	391	27	or	or	CCONJ
fnp-3766	391	28	app	app	ADJ
fnp-3766	391	29	/	/	SYM
fnp-3766	391	30	asyn	asyn	PROPN
fnp-3766	391	31	.	.	PUNCT
fnp-3766	392	1	seeded	seed	VERB
fnp-3766	392	2	mice	mouse	NOUN
fnp-3766	392	3	with	with	ADP
fnp-3766	392	4	diffuse	diffuse	NOUN
fnp-3766	392	5	aβ	aβ	PRON
fnp-3766	392	6	pathology	pathology	NOUN
fnp-3766	392	7	were	be	AUX
fnp-3766	392	8	not	not	PART
fnp-3766	392	9	impaired	impair	VERB
fnp-3766	392	10	in	in	ADP
fnp-3766	392	11	a	a	DET
fnp-3766	392	12	fear	fear	NOUN
fnp-3766	392	13	-	-	PUNCT
fnp-3766	392	14	conditioning	conditioning	NOUN
fnp-3766	392	15	memory	memory	NOUN
fnp-3766	392	16	task	task	NOUN
fnp-3766	392	17	.	.	PUNCT
fnp-3766	393	1	the	the	DET
fnp-3766	393	2	seeding	seed	VERB
fnp-3766	393	3	approach	approach	NOUN
fnp-3766	393	4	described	describe	VERB
fnp-3766	393	5	here	here	ADV
fnp-3766	393	6	may	may	AUX
fnp-3766	393	7	be	be	AUX
fnp-3766	393	8	useful	useful	ADJ
fnp-3766	393	9	in	in	ADP
fnp-3766	393	10	producing	produce	VERB
fnp-3766	393	11	mice	mouse	NOUN
fnp-3766	393	12	that	that	PRON
fnp-3766	393	13	model	model	NOUN
fnp-3766	393	14	aspects	aspect	NOUN
fnp-3766	393	15	of	of	ADP
fnp-3766	393	16	non	non	ADJ
fnp-3766	393	17	-	-	ADJ
fnp-3766	393	18	ad	ad	ADJ
fnp-3766	393	19	pathological	pathological	ADJ
fnp-3766	393	20	aging	aging	NOUN
fnp-3766	393	21	,	,	PUNCT
fnp-3766	393	22	providing	provide	VERB
fnp-3766	393	23	a	a	DET
fnp-3766	393	24	useful	useful	ADJ
fnp-3766	393	25	comparison	comparison	NOUN
fnp-3766	393	26	model	model	NOUN
fnp-3766	393	27	to	to	ADP
fnp-3766	393	28	mice	mouse	NOUN
fnp-3766	393	29	that	that	PRON
fnp-3766	393	30	exhibit	exhibit	VERB
fnp-3766	393	31	pathological	pathological	ADJ
fnp-3766	393	32	features	feature	VERB
fnp-3766	393	33	more	more	ADV
fnp-3766	393	34	similar	similar	ADJ
fnp-3766	393	35	to	to	ADP
fnp-3766	393	36	ad	ad	NOUN
fnp-3766	393	37	and	and	CCONJ
fnp-3766	393	38	ad	ad	NOUN
fnp-3766	393	39	/	/	SYM
fnp-3766	393	40	lbd	lbd	PROPN
fnp-3766	393	41	pathology	pathology	PROPN
fnp-3766	393	42	.	.	PUNCT
fnp-3766	394	1	ethics	ethic	NOUN
fnp-3766	394	2	approval	approval	VERB
fnp-3766	394	3	human	human	ADJ
fnp-3766	394	4	brain	brain	NOUN
fnp-3766	394	5	tissue	tissue	NOUN
fnp-3766	394	6	was	be	AUX
fnp-3766	394	7	obtained	obtain	VERB
fnp-3766	394	8	from	from	ADP
fnp-3766	394	9	the	the	DET
fnp-3766	394	10	mayo	mayo	PROPN
fnp-3766	394	11	clinic	clinic	PROPN
fnp-3766	394	12	brain	brain	PROPN
fnp-3766	394	13	bank	bank	PROPN
fnp-3766	394	14	and	and	CCONJ
fnp-3766	394	15	university	university	PROPN
fnp-3766	394	16	of	of	ADP
fnp-3766	394	17	florida	florida	PROPN
fnp-3766	394	18	neuromedicine	neuromedicine	PROPN
fnp-3766	394	19	human	human	ADJ
fnp-3766	394	20	brain	brain	NOUN
fnp-3766	394	21	tissue	tissue	NOUN
fnp-3766	394	22	bank	bank	NOUN
fnp-3766	394	23	with	with	ADP
fnp-3766	394	24	informed	informed	ADJ
fnp-3766	394	25	consent	consent	NOUN
fnp-3766	394	26	following	follow	VERB
fnp-3766	394	27	institutional	institutional	ADJ
fnp-3766	394	28	regulations	regulation	NOUN
fnp-3766	394	29	.	.	PUNCT
fnp-3766	395	1	all	all	DET
fnp-3766	395	2	animal	animal	NOUN
fnp-3766	395	3	procedures	procedure	NOUN
fnp-3766	395	4	were	be	AUX
fnp-3766	395	5	approved	approve	VERB
fnp-3766	395	6	by	by	ADP
fnp-3766	395	7	the	the	DET
fnp-3766	395	8	university	university	PROPN
fnp-3766	395	9	of	of	ADP
fnp-3766	395	10	florida	florida	PROPN
fnp-3766	395	11	institutional	institutional	PROPN
fnp-3766	395	12	animal	animal	NOUN
fnp-3766	395	13	care	care	NOUN
fnp-3766	395	14	and	and	CCONJ
fnp-3766	395	15	use	use	NOUN
fnp-3766	395	16	committee	committee	NOUN
fnp-3766	395	17	.	.	PUNCT
fnp-3766	396	1	consent	consent	NOUN
fnp-3766	396	2	for	for	ADP
fnp-3766	396	3	publication	publication	NOUN
fnp-3766	396	4	not	not	PART
fnp-3766	396	5	applicable	applicable	ADJ
fnp-3766	396	6	.	.	PUNCT
fnp-3766	397	1	availability	availability	NOUN
fnp-3766	397	2	of	of	ADP
fnp-3766	397	3	data	datum	NOUN
fnp-3766	397	4	and	and	CCONJ
fnp-3766	397	5	materials	material	NOUN
fnp-3766	397	6	all	all	DET
fnp-3766	397	7	data	datum	NOUN
fnp-3766	397	8	generated	generate	VERB
fnp-3766	397	9	and	and	CCONJ
fnp-3766	397	10	analyzed	analyze	VERB
fnp-3766	397	11	during	during	ADP
fnp-3766	397	12	this	this	DET
fnp-3766	397	13	study	study	NOUN
fnp-3766	397	14	are	be	AUX
fnp-3766	397	15	included	include	VERB
fnp-3766	397	16	in	in	ADP
fnp-3766	397	17	this	this	DET
fnp-3766	397	18	manuscript	manuscript	NOUN
fnp-3766	397	19	.	.	PUNCT
fnp-3766	398	1	competing	compete	VERB
fnp-3766	398	2	interests	interest	NOUN
fnp-3766	398	3	the	the	DET
fnp-3766	398	4	authors	author	NOUN
fnp-3766	398	5	declare	declare	VERB
fnp-3766	398	6	that	that	SCONJ
fnp-3766	398	7	they	they	PRON
fnp-3766	398	8	have	have	VERB
fnp-3766	398	9	no	no	DET
fnp-3766	398	10	competing	compete	VERB
fnp-3766	398	11	interests	interest	NOUN
fnp-3766	398	12	.	.	PUNCT
fnp-3766	399	1	funding	fund	VERB
fnp-3766	399	2	this	this	DET
fnp-3766	399	3	work	work	NOUN
fnp-3766	399	4	was	be	AUX
fnp-3766	399	5	supported	support	VERB
fnp-3766	399	6	by	by	ADP
fnp-3766	399	7	funding	funding	NOUN
fnp-3766	399	8	from	from	ADP
fnp-3766	399	9	the	the	DET
fnp-3766	399	10	national	national	PROPN
fnp-3766	399	11	institute	institute	PROPN
fnp-3766	399	12	of	of	ADP
fnp-3766	399	13	health	health	NOUN
fnp-3766	399	14	;	;	PUNCT
fnp-3766	399	15	grant	grant	NOUN
fnp-3766	399	16	numbers	number	NOUN
fnp-3766	399	17	r21ag046125	r21ag046125	PROPN
fnp-3766	399	18	,	,	PUNCT
fnp-3766	399	19	r21ag055113	r21ag055113	PROPN
fnp-3766	399	20	,	,	PUNCT
fnp-3766	399	21	u54ns110435	u54ns110435	NOUN
fnp-3766	399	22	,	,	PUNCT
fnp-3766	399	23	p50ag047266	p50ag047266	NOUN
fnp-3766	399	24	,	,	PUNCT
fnp-3766	399	25	p30ag066506	p30ag066506	NOUN
fnp-3766	399	26	.	.	PUNCT
fnp-3766	400	1	authors	author	NOUN
fnp-3766	400	2	’	’	PART
fnp-3766	400	3	contributions	contribution	NOUN
fnp-3766	400	4	study	study	VERB
fnp-3766	400	5	concept	concept	NOUN
fnp-3766	400	6	and	and	CCONJ
fnp-3766	400	7	design	design	NOUN
fnp-3766	400	8	:	:	PUNCT
fnp-3766	400	9	bdm	bdm	NOUN
fnp-3766	400	10	,	,	PUNCT
fnp-3766	400	11	yl	yl	NOUN
fnp-3766	400	12	,	,	PUNCT
fnp-3766	400	13	jl	jl	NOUN
fnp-3766	400	14	,	,	PUNCT
fnp-3766	400	15	big	big	ADJ
fnp-3766	400	16	,	,	PUNCT
fnp-3766	400	17	drb	drb	PROPN
fnp-3766	400	18	.	.	PUNCT
fnp-3766	401	1	pathological	pathological	ADJ
fnp-3766	401	2	analysis	analysis	NOUN
fnp-3766	401	3	:	:	PUNCT
fnp-3766	401	4	sp	sp	ADP
fnp-3766	401	5	and	and	CCONJ
fnp-3766	401	6	dd	dd	PROPN
fnp-3766	401	7	.	.	PROPN
fnp-3766	401	8	acquisition	acquisition	NOUN
fnp-3766	401	9	of	of	ADP
fnp-3766	401	10	data	datum	NOUN
fnp-3766	401	11	:	:	PUNCT
fnp-3766	401	12	bdm	bdm	NOUN
fnp-3766	401	13	,	,	PUNCT
fnp-3766	401	14	yl	yl	NOUN
fnp-3766	401	15	,	,	PUNCT
fnp-3766	401	16	gx	gx	PROPN
fnp-3766	401	17	,	,	PUNCT
fnp-3766	401	18	hh	hh	PROPN
fnp-3766	401	19	,	,	PUNCT
fnp-3766	401	20	mfa	mfa	PROPN
fnp-3766	401	21	,	,	PUNCT
fnp-3766	401	22	clc	clc	PROPN
fnp-3766	401	23	,	,	PUNCT
fnp-3766	401	24	hsf	hsf	NOUN
fnp-3766	401	25	,	,	PUNCT
fnp-3766	401	26	cm	cm	PROPN
fnp-3766	401	27	,	,	PUNCT
fnp-3766	401	28	sf	sf	PROPN
fnp-3766	401	29	,	,	PUNCT
fnp-3766	401	30	sp	sp	NOUN
fnp-3766	401	31	,	,	PUNCT
fnp-3766	401	32	dd	dd	NOUN
fnp-3766	401	33	.	.	NOUN
fnp-3766	401	34	statistical	statistical	ADJ
fnp-3766	401	35	analysis	analysis	NOUN
fnp-3766	401	36	:	:	PUNCT
fnp-3766	401	37	bdm	bdm	NOUN
fnp-3766	401	38	and	and	CCONJ
fnp-3766	401	39	drb	drb	PROPN
fnp-3766	401	40	.	.	PROPN
fnp-3766	401	41	analysis	analysis	NOUN
fnp-3766	401	42	and	and	CCONJ
fnp-3766	401	43	interpretation	interpretation	NOUN
fnp-3766	401	44	of	of	ADP
fnp-3766	401	45	the	the	DET
fnp-3766	401	46	data	datum	NOUN
fnp-3766	401	47	:	:	PUNCT
fnp-3766	401	48	bdm	bdm	NOUN
fnp-3766	401	49	,	,	PUNCT
fnp-3766	401	50	yl	yl	NOUN
fnp-3766	401	51	,	,	PUNCT
fnp-3766	401	52	gx	gx	PROPN
fnp-3766	401	53	,	,	PUNCT
fnp-3766	401	54	cj	cj	PROPN
fnp-3766	401	55	,	,	PUNCT
fnp-3766	401	56	jl	jl	NOUN
fnp-3766	401	57	,	,	PUNCT
fnp-3766	401	58	big	big	ADJ
fnp-3766	401	59	,	,	PUNCT
fnp-3766	401	60	teg	teg	NOUN
fnp-3766	401	61	,	,	PUNCT
fnp-3766	401	62	drb	drb	PROPN
fnp-3766	401	63	.	.	PUNCT
fnp-3766	401	64	drafting	drafting	NOUN
fnp-3766	401	65	of	of	ADP
fnp-3766	401	66	the	the	DET
fnp-3766	401	67	manuscript	manuscript	NOUN
fnp-3766	401	68	:	:	PUNCT
fnp-3766	401	69	bdm	bdm	NOUN
fnp-3766	401	70	and	and	CCONJ
fnp-3766	401	71	drb	drb	PROPN
fnp-3766	401	72	.	.	PROPN
fnp-3766	401	73	acquisition	acquisition	NOUN
fnp-3766	401	74	of	of	ADP
fnp-3766	401	75	funding	funding	NOUN
fnp-3766	401	76	:	:	PUNCT
fnp-3766	401	77	jl	jl	NOUN
fnp-3766	401	78	,	,	PUNCT
fnp-3766	401	79	big	big	ADJ
fnp-3766	401	80	,	,	PUNCT
fnp-3766	401	81	teg	teg	NOUN
fnp-3766	401	82	,	,	PUNCT
fnp-3766	401	83	drb	drb	PROPN
fnp-3766	401	84	.	.	PUNCT
fnp-3766	402	1	all	all	DET
fnp-3766	402	2	authors	author	NOUN
fnp-3766	402	3	read	read	VERB
fnp-3766	402	4	and	and	CCONJ
fnp-3766	402	5	approved	approve	VERB
fnp-3766	402	6	the	the	DET
fnp-3766	402	7	final	final	ADJ
fnp-3766	402	8	manuscript	manuscript	NOUN
fnp-3766	402	9	.	.	PUNCT
fnp-3766	403	1	acknowledgements	acknowledgement	NOUN
fnp-3766	403	2	the	the	DET
fnp-3766	403	3	authors	author	NOUN
fnp-3766	403	4	would	would	AUX
fnp-3766	403	5	like	like	VERB
fnp-3766	403	6	to	to	PART
fnp-3766	403	7	thank	thank	VERB
fnp-3766	403	8	the	the	DET
fnp-3766	403	9	patients	patient	NOUN
fnp-3766	403	10	and	and	CCONJ
fnp-3766	403	11	their	their	PRON
fnp-3766	403	12	families	family	NOUN
fnp-3766	403	13	that	that	PRON
fnp-3766	403	14	donated	donate	VERB
fnp-3766	403	15	tissue	tissue	NOUN
fnp-3766	403	16	.	.	PUNCT
fnp-3766	404	1	we	we	PRON
fnp-3766	404	2	thank	thank	VERB
fnp-3766	404	3	dr	dr	PROPN
fnp-3766	404	4	.	.	PROPN
fnp-3766	404	5	peter	peter	PROPN
fnp-3766	404	6	davies	davies	PROPN
fnp-3766	404	7	(	(	PUNCT
fnp-3766	404	8	feinstein	feinstein	PROPN
fnp-3766	404	9	institute	institute	PROPN
fnp-3766	404	10	for	for	ADP
fnp-3766	404	11	medical	medical	ADJ
fnp-3766	404	12	research	research	NOUN
fnp-3766	404	13	,	,	PUNCT
fnp-3766	404	14	manhasset	manhasset	PROPN
fnp-3766	404	15	,	,	PUNCT
fnp-3766	404	16	ny	ny	PROPN
fnp-3766	404	17	,	,	PUNCT
fnp-3766	404	18	usa	usa	PROPN
fnp-3766	404	19	)	)	PUNCT
fnp-3766	404	20	posthumously	posthumously	ADV
fnp-3766	404	21	for	for	ADP
fnp-3766	404	22	antibodies	antibody	NOUN
fnp-3766	404	23	to	to	ADP
fnp-3766	404	24	tau	tau	PROPN
fnp-3766	404	25	.	.	PUNCT
fnp-3766	405	1	conflict	conflict	NOUN
fnp-3766	405	2	of	of	ADP
fnp-3766	405	3	interest	interest	NOUN
fnp-3766	405	4	teg	teg	PROPN
fnp-3766	405	5	is	be	AUX
fnp-3766	405	6	a	a	DET
fnp-3766	405	7	co	co	NOUN
fnp-3766	405	8	-	-	NOUN
fnp-3766	405	9	founder	founder	NOUN
fnp-3766	405	10	of	of	ADP
fnp-3766	405	11	lacerta	lacerta	PROPN
fnp-3766	405	12	therapeutics	therapeutic	NOUN
fnp-3766	405	13	.	.	PUNCT
fnp-3766	406	1	references	reference	NOUN
fnp-3766	406	2	1	1	NUM
fnp-3766	406	3	.	.	PUNCT
fnp-3766	406	4	hardy	hardy	PROPN
fnp-3766	406	5	ja	ja	PROPN
fnp-3766	406	6	,	,	PUNCT
fnp-3766	406	7	higgins	higgins	PROPN
fnp-3766	406	8	ga	ga	PROPN
fnp-3766	406	9	.	.	PROPN
fnp-3766	406	10	alzheimer	alzheimer	PROPN
fnp-3766	406	11	's	's	PART
fnp-3766	406	12	disease	disease	NOUN
fnp-3766	406	13	:	:	PUNCT
fnp-3766	406	14	the	the	DET
fnp-3766	406	15	amyloid	amyloid	NOUN
fnp-3766	406	16	cascade	cascade	NOUN
fnp-3766	406	17	hypothesis	hypothesis	NOUN
fnp-3766	406	18	.	.	PUNCT
fnp-3766	407	1	science	science	NOUN
fnp-3766	407	2	.	.	PUNCT
fnp-3766	408	1	1992;256(5054):184	1992;256(5054):184	NUM
fnp-3766	408	2	-	-	SYM
fnp-3766	408	3	5	5	NUM
fnp-3766	408	4	.	.	NOUN
fnp-3766	408	5	2	2	NUM
fnp-3766	408	6	.	.	X
fnp-3766	408	7	selkoe	selkoe	PROPN
fnp-3766	408	8	dj	dj	NOUN
fnp-3766	408	9	,	,	PUNCT
fnp-3766	408	10	hardy	hardy	ADJ
fnp-3766	408	11	j.	j.	PROPN
fnp-3766	408	12	the	the	DET
fnp-3766	408	13	amyloid	amyloid	NOUN
fnp-3766	408	14	hypothesis	hypothesis	NOUN
fnp-3766	408	15	of	of	ADP
fnp-3766	408	16	alzheimer	alzheimer	PROPN
fnp-3766	408	17	's	's	PART
fnp-3766	408	18	disease	disease	NOUN
fnp-3766	408	19	at	at	ADP
fnp-3766	408	20	25	25	NUM
fnp-3766	408	21	years	year	NOUN
fnp-3766	408	22	.	.	PUNCT
fnp-3766	409	1	embo	embo	NOUN
fnp-3766	409	2	mol	mol	ADP
fnp-3766	409	3	med	med	PROPN
fnp-3766	409	4	.	.	PUNCT
fnp-3766	410	1	2016;8(6):595	2016;8(6):595	NUM
fnp-3766	410	2	-	-	SYM
fnp-3766	410	3	608	608	NUM
fnp-3766	410	4	.	.	PUNCT
fnp-3766	411	1	3	3	X
fnp-3766	411	2	.	.	X
fnp-3766	411	3	lewis	lewis	PROPN
fnp-3766	411	4	j	j	PROPN
fnp-3766	411	5	,	,	PUNCT
fnp-3766	411	6	dickson	dickson	PROPN
fnp-3766	411	7	dw	dw	PROPN
fnp-3766	411	8	,	,	PUNCT
fnp-3766	411	9	lin	lin	PROPN
fnp-3766	411	10	wl	wl	PROPN
fnp-3766	411	11	,	,	PUNCT
fnp-3766	411	12	chisholm	chisholm	PROPN
fnp-3766	411	13	l	l	PROPN
fnp-3766	411	14	,	,	PUNCT
fnp-3766	411	15	corral	corral	PROPN
fnp-3766	411	16	a	a	NOUN
fnp-3766	411	17	,	,	PUNCT
fnp-3766	411	18	jones	jones	PROPN
fnp-3766	411	19	g	g	PROPN
fnp-3766	411	20	,	,	PUNCT
fnp-3766	411	21	et	et	PROPN
fnp-3766	411	22	al	al	PROPN
fnp-3766	411	23	.	.	PROPN
fnp-3766	411	24	enhanced	enhance	VERB
fnp-3766	411	25	neurofibrillary	neurofibrillary	ADJ
fnp-3766	411	26	degeneration	degeneration	NOUN
fnp-3766	411	27	in	in	ADP
fnp-3766	411	28	transgenic	transgenic	NOUN
fnp-3766	411	29	mice	mouse	NOUN
fnp-3766	411	30	expressing	express	VERB
fnp-3766	411	31	mutant	mutant	NOUN
fnp-3766	411	32	tau	tau	PROPN
fnp-3766	411	33	and	and	CCONJ
fnp-3766	411	34	app	app	PROPN
fnp-3766	411	35	.	.	PROPN
fnp-3766	412	1	science	science	PROPN
fnp-3766	412	2	.	.	PUNCT
fnp-3766	413	1	2001;293(5534):1487	2001;293(5534):1487	NUM
fnp-3766	413	2	-	-	SYM
fnp-3766	413	3	91	91	NUM
fnp-3766	413	4	.	.	PUNCT
fnp-3766	414	1	4	4	X
fnp-3766	414	2	.	.	X
fnp-3766	414	3	oddo	oddo	PROPN
fnp-3766	414	4	s	s	PART
fnp-3766	414	5	,	,	PUNCT
fnp-3766	414	6	caccamo	caccamo	VERB
fnp-3766	414	7	a	a	DET
fnp-3766	414	8	,	,	PUNCT
fnp-3766	414	9	shepherd	shepherd	PROPN
fnp-3766	414	10	jd	jd	PROPN
fnp-3766	414	11	,	,	PUNCT
fnp-3766	414	12	murphy	murphy	PROPN
fnp-3766	414	13	mp	mp	PROPN
fnp-3766	414	14	,	,	PUNCT
fnp-3766	414	15	golde	golde	PROPN
fnp-3766	414	16	te	te	PROPN
fnp-3766	414	17	,	,	PUNCT
fnp-3766	414	18	kayed	kaye	VERB
fnp-3766	414	19	r	r	NOUN
fnp-3766	414	20	,	,	PUNCT
fnp-3766	414	21	et	et	PROPN
fnp-3766	414	22	al	al	PROPN
fnp-3766	414	23	.	.	PUNCT
fnp-3766	415	1	triple	triple	ADJ
fnp-3766	415	2	-	-	PUNCT
fnp-3766	415	3	transgenic	transgenic	NOUN
fnp-3766	415	4	model	model	NOUN
fnp-3766	415	5	of	of	ADP
fnp-3766	415	6	alzheimer	alzheimer	PROPN
fnp-3766	415	7	's	's	PART
fnp-3766	415	8	disease	disease	NOUN
fnp-3766	415	9	with	with	ADP
fnp-3766	415	10	plaques	plaque	NOUN
fnp-3766	415	11	and	and	CCONJ
fnp-3766	415	12	tangles	tangle	NOUN
fnp-3766	415	13	:	:	PUNCT
fnp-3766	415	14	intracellular	intracellular	ADJ
fnp-3766	415	15	abeta	abeta	ADJ
fnp-3766	415	16	and	and	CCONJ
fnp-3766	415	17	synaptic	synaptic	ADJ
fnp-3766	415	18	dysfunction	dysfunction	NOUN
fnp-3766	415	19	.	.	PUNCT
fnp-3766	416	1	neuron	neuron	PROPN
fnp-3766	416	2	.	.	PUNCT
fnp-3766	417	1	2003;39(3):409	2003;39(3):409	NUM
fnp-3766	417	2	-	-	SYM
fnp-3766	417	3	21	21	NUM
fnp-3766	417	4	.	.	PUNCT
fnp-3766	418	1	5	5	X
fnp-3766	418	2	.	.	X
fnp-3766	418	3	paulson	paulson	PROPN
fnp-3766	418	4	jb	jb	PROPN
fnp-3766	418	5	,	,	PUNCT
fnp-3766	418	6	ramsden	ramsden	PROPN
fnp-3766	418	7	m	m	PROPN
fnp-3766	418	8	,	,	PUNCT
fnp-3766	418	9	forster	forster	PROPN
fnp-3766	418	10	c	c	PROPN
fnp-3766	418	11	,	,	PUNCT
fnp-3766	418	12	sherman	sherman	PROPN
fnp-3766	418	13	ma	ma	PROPN
fnp-3766	418	14	,	,	PUNCT
fnp-3766	418	15	mcgowan	mcgowan	PROPN
fnp-3766	418	16	e	e	PROPN
fnp-3766	418	17	,	,	PUNCT
fnp-3766	418	18	ashe	ashe	PROPN
fnp-3766	418	19	kh	kh	PROPN
fnp-3766	418	20	.	.	PUNCT
fnp-3766	418	21	amyloid	amyloid	PROPN
fnp-3766	418	22	plaque	plaque	NOUN
fnp-3766	418	23	and	and	CCONJ
fnp-3766	418	24	neurofibrillary	neurofibrillary	ADJ
fnp-3766	418	25	tangle	tangle	NOUN
fnp-3766	418	26	pathology	pathology	NOUN
fnp-3766	418	27	in	in	ADP
fnp-3766	418	28	a	a	DET
fnp-3766	418	29	regulatable	regulatable	ADJ
fnp-3766	418	30	mouse	mouse	NOUN
fnp-3766	418	31	model	model	NOUN
fnp-3766	418	32	of	of	ADP
fnp-3766	418	33	alzheimer	alzheimer	PROPN
fnp-3766	418	34	's	's	PART
fnp-3766	418	35	disease	disease	NOUN
fnp-3766	418	36	.	.	PUNCT
fnp-3766	419	1	am	be	AUX
fnp-3766	419	2	j	j	PROPN
fnp-3766	419	3	pathol	pathol	NOUN
fnp-3766	419	4	.	.	PUNCT
fnp-3766	420	1	2008;173(3):762	2008;173(3):762	NUM
fnp-3766	420	2	-	-	SYM
fnp-3766	420	3	72	72	NUM
fnp-3766	420	4	.	.	NOUN
fnp-3766	421	1	6	6	NUM
fnp-3766	421	2	.	.	X
fnp-3766	421	3	guo	guo	PROPN
fnp-3766	421	4	q	q	PROPN
fnp-3766	421	5	,	,	PUNCT
fnp-3766	421	6	li	li	PROPN
fnp-3766	421	7	h	h	PROPN
fnp-3766	421	8	,	,	PUNCT
fnp-3766	421	9	cole	cole	PROPN
fnp-3766	421	10	al	al	PROPN
fnp-3766	421	11	,	,	PUNCT
fnp-3766	421	12	hur	hur	PROPN
fnp-3766	421	13	jy	jy	PROPN
fnp-3766	421	14	,	,	PUNCT
fnp-3766	421	15	li	li	PROPN
fnp-3766	421	16	y	y	PROPN
fnp-3766	421	17	,	,	PUNCT
fnp-3766	421	18	zheng	zheng	PROPN
fnp-3766	421	19	h.	h.	PROPN
fnp-3766	422	1	modeling	modeling	PROPN
fnp-3766	422	2	alzheimer	alzheimer	PROPN
fnp-3766	422	3	's	's	PART
fnp-3766	422	4	disease	disease	NOUN
fnp-3766	422	5	in	in	ADP
fnp-3766	422	6	mouse	mouse	NOUN
fnp-3766	422	7	without	without	ADP
fnp-3766	422	8	mutant	mutant	ADJ
fnp-3766	422	9	protein	protein	NOUN
fnp-3766	422	10	overexpression	overexpression	NOUN
fnp-3766	422	11	:	:	PUNCT
fnp-3766	422	12	cooperative	cooperative	ADJ
fnp-3766	422	13	and	and	CCONJ
fnp-3766	422	14	independent	independent	ADJ
fnp-3766	422	15	effects	effect	NOUN
fnp-3766	422	16	of	of	ADP
fnp-3766	422	17	abeta	abeta	PROPN
fnp-3766	422	18	and	and	CCONJ
fnp-3766	422	19	tau	tau	PROPN
fnp-3766	422	20	.	.	PUNCT
fnp-3766	423	1	plos	plos	PROPN
fnp-3766	423	2	one	one	NUM
fnp-3766	423	3	.	.	PUNCT
fnp-3766	424	1	2013;8(11):e80706	2013;8(11):e80706	NOUN
fnp-3766	424	2	.	.	NOUN
fnp-3766	424	3	7	7	NUM
fnp-3766	424	4	.	.	X
fnp-3766	424	5	angulo	angulo	PROPN
fnp-3766	424	6	sl	sl	PROPN
fnp-3766	424	7	,	,	PUNCT
fnp-3766	424	8	orman	orman	PROPN
fnp-3766	424	9	r	r	PROPN
fnp-3766	424	10	,	,	PUNCT
fnp-3766	424	11	neymotin	neymotin	PROPN
fnp-3766	424	12	sa	sa	PROPN
fnp-3766	424	13	,	,	PUNCT
fnp-3766	424	14	liu	liu	PROPN
fnp-3766	424	15	l	l	PROPN
fnp-3766	424	16	,	,	PUNCT
fnp-3766	424	17	buitrago	buitrago	PROPN
fnp-3766	424	18	l	l	PROPN
fnp-3766	424	19	,	,	PUNCT
fnp-3766	424	20	cepeda	cepeda	PROPN
fnp-3766	424	21	-	-	PUNCT
fnp-3766	424	22	prado	prado	PROPN
fnp-3766	424	23	e	e	X
fnp-3766	424	24	,	,	PUNCT
fnp-3766	424	25	et	et	PROPN
fnp-3766	424	26	al	al	PROPN
fnp-3766	424	27	.	.	PUNCT
fnp-3766	425	1	tau	tau	PROPN
fnp-3766	425	2	and	and	CCONJ
fnp-3766	425	3	amyloid	amyloid	NOUN
fnp-3766	425	4	-	-	PUNCT
fnp-3766	425	5	related	relate	VERB
fnp-3766	425	6	pathologies	pathology	NOUN
fnp-3766	425	7	in	in	ADP
fnp-3766	425	8	the	the	DET
fnp-3766	425	9	entorhinal	entorhinal	ADJ
fnp-3766	425	10	cortex	cortex	NOUN
fnp-3766	425	11	have	have	VERB
fnp-3766	425	12	divergent	divergent	ADJ
fnp-3766	425	13	effects	effect	NOUN
fnp-3766	425	14	in	in	ADP
fnp-3766	425	15	the	the	DET
fnp-3766	425	16	hippocampal	hippocampal	ADJ
fnp-3766	425	17	circuit	circuit	NOUN
fnp-3766	425	18	.	.	PUNCT
fnp-3766	426	1	neurobiol	neurobiol	PROPN
fnp-3766	426	2	dis	dis	PROPN
fnp-3766	426	3	.	.	PUNCT
fnp-3766	427	1	2017;108:261	2017;108:261	NUM
fnp-3766	427	2	-	-	SYM
fnp-3766	427	3	76	76	NUM
fnp-3766	427	4	.	.	NOUN
fnp-3766	428	1	8	8	NUM
fnp-3766	428	2	.	.	X
fnp-3766	428	3	bennett	bennett	PROPN
fnp-3766	428	4	re	re	PROPN
fnp-3766	428	5	,	,	PUNCT
fnp-3766	428	6	devos	devos	PROPN
fnp-3766	428	7	sl	sl	PROPN
fnp-3766	428	8	,	,	PUNCT
fnp-3766	428	9	dujardin	dujardin	PROPN
fnp-3766	428	10	s	s	PROPN
fnp-3766	428	11	,	,	PUNCT
fnp-3766	428	12	corjuc	corjuc	VERB
fnp-3766	428	13	b	b	NUM
fnp-3766	428	14	,	,	PUNCT
fnp-3766	428	15	gor	gor	PROPN
fnp-3766	428	16	r	r	PROPN
fnp-3766	428	17	,	,	PUNCT
fnp-3766	428	18	gonzalez	gonzalez	PROPN
fnp-3766	428	19	j	j	PROPN
fnp-3766	428	20	,	,	PUNCT
fnp-3766	428	21	et	et	PROPN
fnp-3766	428	22	al	al	PROPN
fnp-3766	428	23	.	.	PROPN
fnp-3766	429	1	enhanced	enhance	VERB
fnp-3766	429	2	tau	tau	PROPN
fnp-3766	429	3	aggregation	aggregation	NOUN
fnp-3766	429	4	in	in	ADP
fnp-3766	429	5	the	the	DET
fnp-3766	429	6	presence	presence	NOUN
fnp-3766	429	7	of	of	ADP
fnp-3766	429	8	amyloid	amyloid	NOUN
fnp-3766	429	9	beta	beta	NOUN
fnp-3766	429	10	.	.	PUNCT
fnp-3766	430	1	am	be	AUX
fnp-3766	430	2	j	j	PROPN
fnp-3766	430	3	pathol	pathol	NOUN
fnp-3766	430	4	.	.	PUNCT
fnp-3766	431	1	2017;187(7):1601	2017;187(7):1601	NUM
fnp-3766	431	2	-	-	SYM
fnp-3766	431	3	12	12	NUM
fnp-3766	431	4	.	.	PUNCT
fnp-3766	432	1	9	9	NUM
fnp-3766	432	2	.	.	X
fnp-3766	432	3	rodriguez	rodriguez	PROPN
fnp-3766	432	4	ga	ga	PROPN
fnp-3766	432	5	,	,	PUNCT
fnp-3766	432	6	barrett	barrett	PROPN
fnp-3766	432	7	gm	gm	PROPN
fnp-3766	432	8	,	,	PUNCT
fnp-3766	432	9	duff	duff	PROPN
fnp-3766	432	10	ke	ke	PROPN
fnp-3766	432	11	,	,	PUNCT
fnp-3766	432	12	hussaini	hussaini	PROPN
fnp-3766	432	13	sa	sa	PROPN
fnp-3766	432	14	.	.	PUNCT
fnp-3766	433	1	chemogenetic	chemogenetic	ADJ
fnp-3766	433	2	attenuation	attenuation	NOUN
fnp-3766	433	3	of	of	ADP
fnp-3766	433	4	neuronal	neuronal	ADJ
fnp-3766	433	5	activity	activity	NOUN
fnp-3766	433	6	in	in	ADP
fnp-3766	433	7	the	the	DET
fnp-3766	433	8	entorhinal	entorhinal	ADJ
fnp-3766	433	9	cortex	cortex	NOUN
fnp-3766	433	10	reduces	reduce	VERB
fnp-3766	433	11	abeta	abeta	ADV
fnp-3766	433	12	and	and	CCONJ
fnp-3766	433	13	tau	tau	PROPN
fnp-3766	433	14	pathology	pathology	NOUN
fnp-3766	433	15	in	in	ADP
fnp-3766	433	16	the	the	DET
fnp-3766	433	17	hippocampus	hippocampus	NOUN
fnp-3766	433	18	.	.	PUNCT
fnp-3766	434	1	plos	plos	PROPN
fnp-3766	434	2	biol	biol	PROPN
fnp-3766	434	3	.	.	PUNCT
fnp-3766	435	1	2020;18(8):e3000851	2020;18(8):e3000851	X
fnp-3766	435	2	.	.	NOUN
fnp-3766	435	3	10	10	NUM
fnp-3766	435	4	.	.	PUNCT
fnp-3766	436	1	saul	saul	PROPN
fnp-3766	436	2	a	a	PRON
fnp-3766	436	3	,	,	PUNCT
fnp-3766	436	4	sprenger	sprenger	NOUN
fnp-3766	436	5	f	f	PROPN
fnp-3766	436	6	,	,	PUNCT
fnp-3766	436	7	bayer	bayer	PROPN
fnp-3766	436	8	ta	ta	PROPN
fnp-3766	436	9	,	,	PUNCT
fnp-3766	436	10	wirths	wirth	NOUN
fnp-3766	436	11	o.	o.	PROPN
fnp-3766	436	12	accelerated	accelerate	VERB
fnp-3766	436	13	tau	tau	PROPN
fnp-3766	436	14	pathology	pathology	NOUN
fnp-3766	436	15	with	with	ADP
fnp-3766	436	16	synaptic	synaptic	ADJ
fnp-3766	436	17	and	and	CCONJ
fnp-3766	436	18	neuronal	neuronal	ADJ
fnp-3766	436	19	loss	loss	NOUN
fnp-3766	436	20	in	in	ADP
fnp-3766	436	21	a	a	DET
fnp-3766	436	22	novel	novel	ADJ
fnp-3766	436	23	triple	triple	ADJ
fnp-3766	436	24	transgenic	transgenic	NOUN
fnp-3766	436	25	mouse	mouse	NOUN
fnp-3766	436	26	model	model	NOUN
fnp-3766	436	27	of	of	ADP
fnp-3766	436	28	alzheimer	alzheimer	PROPN
fnp-3766	436	29	's	's	PART
fnp-3766	436	30	disease	disease	NOUN
fnp-3766	436	31	.	.	PUNCT
fnp-3766	437	1	neurobiol	neurobiol	PROPN
fnp-3766	437	2	aging	aging	NOUN
fnp-3766	437	3	.	.	PUNCT
fnp-3766	438	1	2013;34(11):2564	2013;34(11):2564	NUM
fnp-3766	438	2	-	-	SYM
fnp-3766	438	3	73	73	NUM
fnp-3766	438	4	.	.	PUNCT
fnp-3766	439	1	11	11	NUM
fnp-3766	439	2	.	.	PUNCT
fnp-3766	440	1	xu	xu	PROPN
fnp-3766	440	2	g	g	PROPN
fnp-3766	440	3	,	,	PUNCT
fnp-3766	440	4	ulm	ulm	PROPN
fnp-3766	440	5	bs	bs	PROPN
fnp-3766	440	6	,	,	PUNCT
fnp-3766	440	7	howard	howard	PROPN
fnp-3766	440	8	j	j	PROPN
fnp-3766	440	9	,	,	PUNCT
fnp-3766	440	10	fromholt	fromholt	PROPN
fnp-3766	440	11	se	se	PROPN
fnp-3766	440	12	,	,	PUNCT
fnp-3766	440	13	lu	lu	PROPN
fnp-3766	440	14	q	q	PROPN
fnp-3766	440	15	,	,	PUNCT
fnp-3766	440	16	lee	lee	PROPN
fnp-3766	440	17	bb	bb	PROPN
fnp-3766	440	18	,	,	PUNCT
fnp-3766	440	19	et	et	PROPN
fnp-3766	440	20	al	al	PROPN
fnp-3766	440	21	.	.	PUNCT
fnp-3766	441	1	tapping	tap	VERB
fnp-3766	441	2	into	into	ADP
fnp-3766	441	3	the	the	DET
fnp-3766	441	4	potential	potential	NOUN
fnp-3766	441	5	of	of	ADP
fnp-3766	441	6	inducible	inducible	ADJ
fnp-3766	441	7	tau	tau	PROPN
fnp-3766	441	8	/	/	SYM
fnp-3766	441	9	app	app	NOUN
fnp-3766	441	10	transgenic	transgenic	NOUN
fnp-3766	441	11	mice	mouse	NOUN
fnp-3766	441	12	.	.	PUNCT
fnp-3766	442	1	neuropathol	neuropathol	NOUN
fnp-3766	442	2	appl	appl	PROPN
fnp-3766	442	3	neurobiol	neurobiol	PROPN
fnp-3766	442	4	.	.	PUNCT
fnp-3766	443	1	2022;in	2022;in	NUM
fnp-3766	443	2	press	press	NOUN
fnp-3766	443	3	.	.	PUNCT
fnp-3766	444	1	12	12	NUM
fnp-3766	444	2	.	.	PUNCT
fnp-3766	445	1	koller	koller	PROPN
fnp-3766	445	2	ej	ej	PROPN
fnp-3766	445	3	,	,	PUNCT
fnp-3766	445	4	ibanez	ibanez	PROPN
fnp-3766	445	5	kr	kr	PROPN
fnp-3766	445	6	,	,	PUNCT
fnp-3766	445	7	vo	vo	X
fnp-3766	445	8	q	q	PROPN
fnp-3766	445	9	,	,	PUNCT
fnp-3766	445	10	mcfarland	mcfarland	PROPN
fnp-3766	445	11	kn	kn	PROPN
fnp-3766	445	12	,	,	PUNCT
fnp-3766	445	13	gonzalez	gonzalez	PROPN
fnp-3766	445	14	de	de	PROPN
fnp-3766	445	15	la	la	PROPN
fnp-3766	445	16	cruz	cruz	PROPN
fnp-3766	445	17	e	e	PROPN
fnp-3766	445	18	,	,	PUNCT
fnp-3766	445	19	zobel	zobel	PROPN
fnp-3766	445	20	l	l	PROPN
fnp-3766	445	21	,	,	PUNCT
fnp-3766	445	22	et	et	PROPN
fnp-3766	445	23	al	al	PROPN
fnp-3766	445	24	.	.	PROPN
fnp-3766	445	25	combinatorial	combinatorial	PROPN
fnp-3766	445	26	model	model	NOUN
fnp-3766	445	27	of	of	ADP
fnp-3766	445	28	amyloid	amyloid	NOUN
fnp-3766	445	29	beta	beta	NOUN
fnp-3766	445	30	and	and	CCONJ
fnp-3766	445	31	tau	tau	PROPN
fnp-3766	445	32	reveals	reveal	VERB
fnp-3766	445	33	synergy	synergy	NOUN
fnp-3766	445	34	between	between	ADP
fnp-3766	445	35	amyloid	amyloid	NOUN
fnp-3766	445	36	deposits	deposit	NOUN
fnp-3766	445	37	and	and	CCONJ
fnp-3766	445	38	tangle	tangle	VERB
fnp-3766	445	39	formation	formation	NOUN
fnp-3766	445	40	.	.	PUNCT
fnp-3766	446	1	neuropathol	neuropathol	NOUN
fnp-3766	446	2	appl	appl	PROPN
fnp-3766	446	3	neurobiol	neurobiol	PROPN
fnp-3766	446	4	.	.	PUNCT
fnp-3766	447	1	2021;48(2):e12779	2021;48(2):e12779	NUM
fnp-3766	447	2	.	.	NOUN
fnp-3766	447	3	13	13	NUM
fnp-3766	447	4	.	.	PUNCT
fnp-3766	447	5	ulm	ulm	PROPN
fnp-3766	447	6	bs	bs	PROPN
fnp-3766	447	7	,	,	PUNCT
fnp-3766	447	8	borchelt	borchelt	PROPN
fnp-3766	447	9	dr	dr	PROPN
fnp-3766	447	10	,	,	PUNCT
fnp-3766	447	11	moore	moore	PROPN
fnp-3766	447	12	bd	bd	PROPN
fnp-3766	447	13	.	.	PUNCT
fnp-3766	447	14	remodeling	remodel	VERB
fnp-3766	447	15	alzheimer	alzheimer	ADJ
fnp-3766	447	16	-	-	PUNCT
fnp-3766	447	17	amyloidosis	amyloidosis	NOUN
fnp-3766	447	18	models	model	NOUN
fnp-3766	447	19	by	by	ADP
fnp-3766	447	20	seeding	seed	VERB
fnp-3766	447	21	.	.	PUNCT
fnp-3766	448	1	mol	mol	ADP
fnp-3766	448	2	neurodegener	neurodegener	NOUN
fnp-3766	448	3	.	.	PUNCT
fnp-3766	449	1	2021;16(1):8	2021;16(1):8	NUM
fnp-3766	449	2	.	.	PUNCT
fnp-3766	450	1	14	14	NUM
fnp-3766	450	2	.	.	PUNCT
fnp-3766	451	1	vergara	vergara	PROPN
fnp-3766	451	2	c	c	PROPN
fnp-3766	451	3	,	,	PUNCT
fnp-3766	451	4	houben	houben	PROPN
fnp-3766	451	5	s	s	PART
fnp-3766	451	6	,	,	PUNCT
fnp-3766	451	7	suain	suain	NOUN
fnp-3766	451	8	v	v	NOUN
fnp-3766	451	9	,	,	PUNCT
fnp-3766	451	10	yilmaz	yilmaz	PROPN
fnp-3766	451	11	z	z	PROPN
fnp-3766	451	12	,	,	PUNCT
fnp-3766	451	13	de	de	PROPN
fnp-3766	451	14	decker	decker	PROPN
fnp-3766	451	15	r	r	PROPN
fnp-3766	451	16	,	,	PUNCT
fnp-3766	451	17	vanden	vanden	PROPN
fnp-3766	451	18	dries	dry	NOUN
fnp-3766	451	19	v	v	PROPN
fnp-3766	451	20	,	,	PUNCT
fnp-3766	451	21	et	et	PROPN
fnp-3766	451	22	al	al	PROPN
fnp-3766	451	23	.	.	PUNCT
fnp-3766	451	24	amyloid	amyloid	NOUN
fnp-3766	451	25	-	-	PUNCT
fnp-3766	451	26	beta	beta	NOUN
fnp-3766	451	27	pathology	pathology	NOUN
fnp-3766	451	28	enhances	enhance	VERB
fnp-3766	451	29	pathological	pathological	ADJ
fnp-3766	451	30	fibrillary	fibrillary	ADJ
fnp-3766	451	31	tau	tau	NOUN
fnp-3766	451	32	seeding	seeding	NOUN
fnp-3766	451	33	induced	induce	VERB
fnp-3766	451	34	by	by	ADP
fnp-3766	451	35	alzheimer	alzheimer	PROPN
fnp-3766	451	36	phf	phf	PROPN
fnp-3766	451	37	in	in	ADP
fnp-3766	451	38	vivo	vivo	NOUN
fnp-3766	451	39	.	.	PUNCT
fnp-3766	452	1	acta	acta	PROPN
fnp-3766	452	2	neuropathol	neuropathol	PROPN
fnp-3766	452	3	.	.	PUNCT
fnp-3766	453	1	2019;137(3):397	2019;137(3):397	NUM
fnp-3766	453	2	-	-	SYM
fnp-3766	453	3	412	412	NUM
fnp-3766	453	4	.	.	NOUN
fnp-3766	453	5	15	15	NUM
fnp-3766	453	6	.	.	PUNCT
fnp-3766	454	1	nies	nies	PROPN
fnp-3766	454	2	sh	sh	PROPN
fnp-3766	454	3	,	,	PUNCT
fnp-3766	454	4	takahashi	takahashi	PROPN
fnp-3766	454	5	h	h	PROPN
fnp-3766	454	6	,	,	PUNCT
fnp-3766	454	7	herber	herber	PROPN
fnp-3766	454	8	cs	cs	PROPN
fnp-3766	454	9	,	,	PUNCT
fnp-3766	454	10	huttner	huttner	X
fnp-3766	454	11	a	a	NOUN
fnp-3766	454	12	,	,	PUNCT
fnp-3766	454	13	chase	chase	NOUN
fnp-3766	454	14	a	a	PRON
fnp-3766	454	15	,	,	PUNCT
fnp-3766	454	16	strittmatter	strittmatter	NOUN
fnp-3766	454	17	sm	sm	PROPN
fnp-3766	454	18	.	.	PUNCT
fnp-3766	455	1	spreading	spread	VERB
fnp-3766	455	2	of	of	ADP
fnp-3766	455	3	alzheimer	alzheimer	PROPN
fnp-3766	455	4	tau	tau	PROPN
fnp-3766	455	5	seeds	seed	NOUN
fnp-3766	455	6	is	be	AUX
fnp-3766	455	7	enhanced	enhance	VERB
fnp-3766	455	8	by	by	ADP
fnp-3766	455	9	aging	age	VERB
fnp-3766	455	10	and	and	CCONJ
fnp-3766	455	11	template	template	NOUN
fnp-3766	455	12	matching	match	VERB
fnp-3766	455	13	with	with	ADP
fnp-3766	455	14	limited	limited	ADJ
fnp-3766	455	15	impact	impact	NOUN
fnp-3766	455	16	of	of	ADP
fnp-3766	455	17	amyloid	amyloid	NOUN
fnp-3766	455	18	-	-	PUNCT
fnp-3766	455	19	beta	beta	NOUN
fnp-3766	455	20	.	.	PUNCT
fnp-3766	456	1	j	j	PROPN
fnp-3766	456	2	biol	biol	PROPN
fnp-3766	456	3	chem	chem	NOUN
fnp-3766	456	4	.	.	PUNCT
fnp-3766	457	1	2021;297(4):101159	2021;297(4):101159	NUM
fnp-3766	457	2	.	.	PROPN
fnp-3766	458	1	16	16	NUM
fnp-3766	458	2	.	.	PUNCT
fnp-3766	459	1	hansen	hansen	PROPN
fnp-3766	459	2	l	l	PROPN
fnp-3766	459	3	,	,	PUNCT
fnp-3766	459	4	salmon	salmon	NOUN
fnp-3766	459	5	d	d	NOUN
fnp-3766	459	6	,	,	PUNCT
fnp-3766	459	7	galasko	galasko	PROPN
fnp-3766	459	8	d	d	PROPN
fnp-3766	459	9	,	,	PUNCT
fnp-3766	459	10	masliah	masliah	PROPN
fnp-3766	459	11	e	e	PROPN
fnp-3766	459	12	,	,	PUNCT
fnp-3766	459	13	katzman	katzman	PROPN
fnp-3766	459	14	r	r	NOUN
fnp-3766	459	15	,	,	PUNCT
fnp-3766	459	16	deteresa	deteresa	NOUN
fnp-3766	459	17	r	r	NOUN
fnp-3766	459	18	,	,	PUNCT
fnp-3766	459	19	et	et	PROPN
fnp-3766	459	20	al	al	PROPN
fnp-3766	459	21	.	.	PUNCT
fnp-3766	460	1	the	the	DET
fnp-3766	460	2	lewy	lewy	PROPN
fnp-3766	460	3	body	body	NOUN
fnp-3766	460	4	variant	variant	NOUN
fnp-3766	460	5	of	of	ADP
fnp-3766	460	6	alzheimer	alzheimer	PROPN
fnp-3766	460	7	's	's	PART
fnp-3766	460	8	disease	disease	NOUN
fnp-3766	460	9	:	:	PUNCT
fnp-3766	460	10	a	a	DET
fnp-3766	460	11	clinical	clinical	ADJ
fnp-3766	460	12	and	and	CCONJ
fnp-3766	460	13	pathologic	pathologic	ADJ
fnp-3766	460	14	entity	entity	NOUN
fnp-3766	460	15	.	.	PUNCT
fnp-3766	461	1	neurology	neurology	NOUN
fnp-3766	461	2	.	.	PUNCT
fnp-3766	462	1	1990;40(1):1	1990;40(1):1	NUM
fnp-3766	462	2	-	-	SYM
fnp-3766	462	3	8	8	NUM
fnp-3766	462	4	.	.	PUNCT
fnp-3766	462	5	17	17	NUM
fnp-3766	462	6	.	.	PUNCT
fnp-3766	462	7	perry	perry	PROPN
fnp-3766	462	8	rh	rh	PROPN
fnp-3766	462	9	,	,	PUNCT
fnp-3766	462	10	irving	irving	PROPN
fnp-3766	462	11	d	d	PROPN
fnp-3766	462	12	,	,	PUNCT
fnp-3766	462	13	blessed	bless	VERB
fnp-3766	462	14	g	g	PROPN
fnp-3766	462	15	,	,	PUNCT
fnp-3766	462	16	fairbairn	fairbairn	PROPN
fnp-3766	462	17	a	a	X
fnp-3766	462	18	,	,	PUNCT
fnp-3766	462	19	perry	perry	PROPN
fnp-3766	462	20	ek	ek	PROPN
fnp-3766	462	21	.	.	PROPN
fnp-3766	462	22	senile	senile	ADJ
fnp-3766	462	23	dementia	dementia	NOUN
fnp-3766	462	24	of	of	ADP
fnp-3766	462	25	lewy	lewy	PROPN
fnp-3766	462	26	body	body	NOUN
fnp-3766	462	27	type	type	NOUN
fnp-3766	462	28	.	.	PUNCT
fnp-3766	463	1	a	a	DET
fnp-3766	463	2	clinically	clinically	ADV
fnp-3766	463	3	and	and	CCONJ
fnp-3766	463	4	neuropathologically	neuropathologically	ADV
fnp-3766	463	5	distinct	distinct	ADJ
fnp-3766	463	6	form	form	NOUN
fnp-3766	463	7	of	of	ADP
fnp-3766	463	8	lewy	lewy	PROPN
fnp-3766	463	9	body	body	NOUN
fnp-3766	463	10	dementia	dementia	NOUN
fnp-3766	463	11	in	in	ADP
fnp-3766	463	12	the	the	DET
fnp-3766	463	13	elderly	elderly	ADJ
fnp-3766	463	14	.	.	PUNCT
fnp-3766	464	1	j	j	PROPN
fnp-3766	464	2	neurol	neurol	PROPN
fnp-3766	464	3	sci	sci	PROPN
fnp-3766	464	4	.	.	PUNCT
fnp-3766	465	1	1990;95(2):119	1990;95(2):119	NUM
fnp-3766	465	2	-	-	SYM
fnp-3766	465	3	39	39	NUM
fnp-3766	465	4	.	.	PUNCT
fnp-3766	466	1	18	18	NUM
fnp-3766	466	2	.	.	X
fnp-3766	467	1	clinton	clinton	PROPN
fnp-3766	467	2	lk	lk	PROPN
fnp-3766	467	3	,	,	PUNCT
fnp-3766	467	4	blurton	blurton	PROPN
fnp-3766	467	5	-	-	PUNCT
fnp-3766	467	6	jones	jones	PROPN
fnp-3766	467	7	m	m	PROPN
fnp-3766	467	8	,	,	PUNCT
fnp-3766	467	9	myczek	myczek	ADJ
fnp-3766	467	10	k	k	NOUN
fnp-3766	467	11	,	,	PUNCT
fnp-3766	467	12	trojanowski	trojanowski	PROPN
fnp-3766	467	13	jq	jq	PROPN
fnp-3766	467	14	,	,	PUNCT
fnp-3766	467	15	laferla	laferla	PROPN
fnp-3766	467	16	fm	fm	PROPN
fnp-3766	467	17	.	.	PUNCT
fnp-3766	467	18	synergistic	synergistic	ADJ
fnp-3766	467	19	interactions	interaction	NOUN
fnp-3766	467	20	between	between	ADP
fnp-3766	467	21	abeta	abeta	PROPN
fnp-3766	467	22	,	,	PUNCT
fnp-3766	467	23	tau	tau	PROPN
fnp-3766	467	24	,	,	PUNCT
fnp-3766	467	25	and	and	CCONJ
fnp-3766	467	26	alpha	alpha	NOUN
fnp-3766	467	27	-	-	PUNCT
fnp-3766	467	28	synuclein	synuclein	NOUN
fnp-3766	467	29	:	:	PUNCT
fnp-3766	467	30	acceleration	acceleration	NOUN
fnp-3766	467	31	of	of	ADP
fnp-3766	467	32	neuropathology	neuropathology	NOUN
fnp-3766	467	33	and	and	CCONJ
fnp-3766	467	34	cognitive	cognitive	ADJ
fnp-3766	467	35	decline	decline	NOUN
fnp-3766	467	36	.	.	PUNCT
fnp-3766	468	1	j	j	PROPN
fnp-3766	468	2	neurosci	neurosci	PROPN
fnp-3766	468	3	.	.	PUNCT
fnp-3766	469	1	2010;30(21):7281	2010;30(21):7281	NUM
fnp-3766	469	2	-	-	SYM
fnp-3766	469	3	9	9	NUM
fnp-3766	469	4	.	.	NOUN
fnp-3766	469	5	19	19	NUM
fnp-3766	469	6	.	.	PUNCT
fnp-3766	469	7	masliah	masliah	PROPN
fnp-3766	469	8	e	e	PROPN
fnp-3766	469	9	,	,	PUNCT
fnp-3766	469	10	rockenstein	rockenstein	PROPN
fnp-3766	469	11	e	e	PROPN
fnp-3766	469	12	,	,	PUNCT
fnp-3766	469	13	veinbergs	veinbergs	PROPN
fnp-3766	469	14	i	i	PRON
fnp-3766	469	15	,	,	PUNCT
fnp-3766	469	16	sagara	sagara	PROPN
fnp-3766	469	17	y	y	PROPN
fnp-3766	469	18	,	,	PUNCT
fnp-3766	469	19	mallory	mallory	PROPN
fnp-3766	469	20	m	m	PROPN
fnp-3766	469	21	,	,	PUNCT
fnp-3766	469	22	hashimoto	hashimoto	NOUN
fnp-3766	469	23	m	m	PROPN
fnp-3766	469	24	,	,	PUNCT
fnp-3766	469	25	et	et	PROPN
fnp-3766	469	26	al	al	PROPN
fnp-3766	469	27	.	.	PUNCT
fnp-3766	470	1	beta	beta	NOUN
fnp-3766	470	2	-	-	PUNCT
fnp-3766	470	3	amyloid	amyloid	NOUN
fnp-3766	470	4	peptides	peptide	NOUN
fnp-3766	470	5	enhance	enhance	VERB
fnp-3766	470	6	alpha	alpha	NOUN
fnp-3766	470	7	-	-	PUNCT
fnp-3766	470	8	synuclein	synuclein	NOUN
fnp-3766	470	9	accumulation	accumulation	NOUN
fnp-3766	470	10	and	and	CCONJ
fnp-3766	470	11	neuronal	neuronal	ADJ
fnp-3766	470	12	deficits	deficit	NOUN
fnp-3766	470	13	in	in	ADP
fnp-3766	470	14	a	a	DET
fnp-3766	470	15	transgenic	transgenic	NOUN
fnp-3766	470	16	mouse	mouse	NOUN
fnp-3766	470	17	model	model	NOUN
fnp-3766	470	18	linking	link	VERB
fnp-3766	470	19	alzheimer	alzheimer	PROPN
fnp-3766	470	20	's	's	PART
fnp-3766	470	21	disease	disease	NOUN
fnp-3766	470	22	and	and	CCONJ
fnp-3766	470	23	parkinson	parkinson	NOUN
fnp-3766	470	24	's	's	PART
fnp-3766	470	25	disease	disease	NOUN
fnp-3766	470	26	.	.	PUNCT
fnp-3766	471	1	proc	proc	PROPN
fnp-3766	471	2	natl	natl	PROPN
fnp-3766	471	3	acad	acad	PROPN
fnp-3766	471	4	sci	sci	PROPN
fnp-3766	471	5	u	u	PROPN
fnp-3766	471	6	s	s	PROPN
fnp-3766	471	7	a.	a.	NOUN
fnp-3766	471	8	2001;98(21):12245	2001;98(21):12245	PROPN
fnp-3766	471	9	-	-	SYM
fnp-3766	471	10	50	50	NUM
fnp-3766	471	11	.	.	NOUN
fnp-3766	471	12	20	20	NUM
fnp-3766	471	13	.	.	PUNCT
fnp-3766	472	1	bassil	bassil	PROPN
fnp-3766	472	2	f	f	PROPN
fnp-3766	472	3	,	,	PUNCT
fnp-3766	472	4	brown	brown	PROPN
fnp-3766	472	5	hj	hj	PROPN
fnp-3766	472	6	,	,	PUNCT
fnp-3766	472	7	pattabhiraman	pattabhiraman	NOUN
fnp-3766	472	8	s	s	PROPN
fnp-3766	472	9	,	,	PUNCT
fnp-3766	472	10	iwasyk	iwasyk	PROPN
fnp-3766	472	11	je	je	PROPN
fnp-3766	472	12	,	,	PUNCT
fnp-3766	472	13	maghames	maghame	VERB
fnp-3766	472	14	cm	cm	PROPN
fnp-3766	472	15	,	,	PUNCT
fnp-3766	472	16	meymand	meymand	NOUN
fnp-3766	472	17	es	es	PROPN
fnp-3766	472	18	,	,	PUNCT
fnp-3766	472	19	et	et	PROPN
fnp-3766	472	20	al	al	PROPN
fnp-3766	472	21	.	.	PUNCT
fnp-3766	472	22	amyloid	amyloid	NOUN
fnp-3766	472	23	-	-	PUNCT
fnp-3766	472	24	beta	beta	NOUN
fnp-3766	472	25	(	(	PUNCT
fnp-3766	472	26	abeta	abeta	ADJ
fnp-3766	472	27	)	)	PUNCT
fnp-3766	472	28	plaques	plaque	NOUN
fnp-3766	472	29	promote	promote	VERB
fnp-3766	472	30	seeding	seed	VERB
fnp-3766	472	31	and	and	CCONJ
fnp-3766	472	32	spreading	spread	VERB
fnp-3766	472	33	of	of	ADP
fnp-3766	472	34	alpha	alpha	NOUN
fnp-3766	472	35	-	-	PUNCT
fnp-3766	472	36	synuclein	synuclein	NOUN
fnp-3766	472	37	and	and	CCONJ
fnp-3766	472	38	tau	tau	PROPN
fnp-3766	472	39	in	in	ADP
fnp-3766	472	40	a	a	DET
fnp-3766	472	41	mouse	mouse	NOUN
fnp-3766	472	42	model	model	NOUN
fnp-3766	472	43	of	of	ADP
fnp-3766	472	44	lewy	lewy	ADJ
fnp-3766	472	45	body	body	NOUN
fnp-3766	472	46	disorders	disorder	NOUN
fnp-3766	472	47	with	with	ADP
fnp-3766	472	48	abeta	abeta	PROPN
fnp-3766	472	49	pathology	pathology	PROPN
fnp-3766	472	50	.	.	PUNCT
fnp-3766	473	1	neuron	neuron	PROPN
fnp-3766	473	2	.	.	PUNCT
fnp-3766	474	1	2020;105(2):260	2020;105(2):260	NUM
fnp-3766	474	2	-	-	SYM
fnp-3766	474	3	75	75	NUM
fnp-3766	474	4	e6	e6	NOUN
fnp-3766	474	5	.	.	PUNCT
fnp-3766	475	1	21	21	NUM
fnp-3766	475	2	.	.	PUNCT
fnp-3766	476	1	lloyd	lloyd	PROPN
fnp-3766	476	2	gm	gm	PROPN
fnp-3766	476	3	,	,	PUNCT
fnp-3766	476	4	dhillon	dhillon	PROPN
fnp-3766	476	5	js	js	PROPN
fnp-3766	476	6	,	,	PUNCT
fnp-3766	476	7	gorion	gorion	NOUN
fnp-3766	476	8	km	km	PROPN
fnp-3766	476	9	,	,	PUNCT
fnp-3766	476	10	riffe	riffe	PROPN
fnp-3766	476	11	c	c	X
fnp-3766	476	12	,	,	PUNCT
fnp-3766	476	13	fromholt	fromholt	NOUN
fnp-3766	476	14	se	se	PROPN
fnp-3766	476	15	,	,	PUNCT
fnp-3766	476	16	xia	xia	PROPN
fnp-3766	476	17	y	y	PROPN
fnp-3766	476	18	,	,	PUNCT
fnp-3766	476	19	et	et	PROPN
fnp-3766	476	20	al	al	PROPN
fnp-3766	476	21	.	.	PROPN
fnp-3766	476	22	collusion	collusion	NOUN
fnp-3766	476	23	of	of	ADP
fnp-3766	476	24	alpha	alpha	NOUN
fnp-3766	476	25	-	-	PUNCT
fnp-3766	476	26	synuclein	synuclein	NOUN
fnp-3766	476	27	and	and	CCONJ
fnp-3766	476	28	abeta	abeta	NOUN
fnp-3766	476	29	aggravating	aggravating	ADJ
fnp-3766	476	30	co	co	NOUN
fnp-3766	476	31	-	-	NOUN
fnp-3766	476	32	morbidities	morbidity	NOUN
fnp-3766	476	33	in	in	ADP
fnp-3766	476	34	a	a	DET
fnp-3766	476	35	novel	novel	ADJ
fnp-3766	476	36	prion	prion	NOUN
fnp-3766	476	37	-	-	PUNCT
fnp-3766	476	38	type	type	NOUN
fnp-3766	476	39	mouse	mouse	NOUN
fnp-3766	476	40	model	model	NOUN
fnp-3766	476	41	.	.	PUNCT
fnp-3766	477	1	mol	mol	ADP
fnp-3766	477	2	neurodegener	neurodegener	NOUN
fnp-3766	477	3	.	.	PUNCT
fnp-3766	478	1	2021;16(1):63	2021;16(1):63	NUM
fnp-3766	478	2	.	.	PUNCT
fnp-3766	479	1	22	22	NUM
fnp-3766	479	2	.	.	PUNCT
fnp-3766	480	1	yamada	yamada	PROPN
fnp-3766	480	2	m	m	PROPN
fnp-3766	480	3	,	,	PUNCT
fnp-3766	480	4	tsukagoshi	tsukagoshi	PROPN
fnp-3766	480	5	h	h	NOUN
fnp-3766	480	6	,	,	PUNCT
fnp-3766	480	7	otomo	otomo	PROPN
fnp-3766	480	8	e	e	PROPN
fnp-3766	480	9	,	,	PUNCT
fnp-3766	480	10	hayakawa	hayakawa	PROPN
fnp-3766	480	11	m.	m.	PROPN
fnp-3766	480	12	systemic	systemic	ADJ
fnp-3766	480	13	amyloid	amyloid	NOUN
fnp-3766	480	14	deposition	deposition	NOUN
fnp-3766	480	15	in	in	ADP
fnp-3766	480	16	old	old	ADJ
fnp-3766	480	17	age	age	NOUN
fnp-3766	480	18	and	and	CCONJ
fnp-3766	480	19	dementia	dementia	NOUN
fnp-3766	480	20	of	of	ADP
fnp-3766	480	21	alzheimer	alzheimer	PROPN
fnp-3766	480	22	type	type	NOUN
fnp-3766	480	23	:	:	PUNCT
fnp-3766	480	24	the	the	DET
fnp-3766	480	25	relationship	relationship	NOUN
fnp-3766	480	26	of	of	ADP
fnp-3766	480	27	brain	brain	NOUN
fnp-3766	480	28	amyloid	amyloid	NOUN
fnp-3766	480	29	to	to	ADP
fnp-3766	480	30	other	other	ADJ
fnp-3766	480	31	amyloid	amyloid	NOUN
fnp-3766	480	32	.	.	PUNCT
fnp-3766	481	1	acta	acta	PROPN
fnp-3766	481	2	neuropathol	neuropathol	PROPN
fnp-3766	481	3	.	.	PUNCT
fnp-3766	482	1	1988;77(2):136	1988;77(2):136	NUM
fnp-3766	482	2	-	-	SYM
fnp-3766	482	3	41	41	NUM
fnp-3766	482	4	.	.	PUNCT
fnp-3766	483	1	23	23	NUM
fnp-3766	483	2	.	.	PUNCT
fnp-3766	484	1	golde	golde	PROPN
fnp-3766	484	2	te	te	PROPN
fnp-3766	484	3	,	,	PUNCT
fnp-3766	484	4	schneider	schneider	PROPN
fnp-3766	484	5	ls	ls	PROPN
fnp-3766	484	6	,	,	PUNCT
fnp-3766	484	7	koo	koo	PROPN
fnp-3766	484	8	eh	eh	INTJ
fnp-3766	484	9	.	.	PUNCT
fnp-3766	484	10	anti	anti	ADJ
fnp-3766	484	11	-	-	ADJ
fnp-3766	484	12	abeta	abeta	ADJ
fnp-3766	484	13	therapeutics	therapeutic	NOUN
fnp-3766	484	14	in	in	ADP
fnp-3766	484	15	alzheimer	alzheimer	PROPN
fnp-3766	484	16	's	's	PART
fnp-3766	484	17	disease	disease	NOUN
fnp-3766	484	18	:	:	PUNCT
fnp-3766	484	19	the	the	DET
fnp-3766	484	20	need	need	NOUN
fnp-3766	484	21	for	for	ADP
fnp-3766	484	22	a	a	DET
fnp-3766	484	23	paradigm	paradigm	NOUN
fnp-3766	484	24	shift	shift	NOUN
fnp-3766	484	25	.	.	PUNCT
fnp-3766	485	1	neuron	neuron	PROPN
fnp-3766	485	2	.	.	PUNCT
fnp-3766	486	1	2011;69(2):203	2011;69(2):203	NUM
fnp-3766	486	2	-	-	SYM
fnp-3766	486	3	13	13	NUM
fnp-3766	486	4	.	.	PUNCT
fnp-3766	487	1	24	24	NUM
fnp-3766	487	2	.	.	PUNCT
fnp-3766	488	1	jack	jack	PROPN
fnp-3766	488	2	cr	cr	PROPN
fnp-3766	488	3	,	,	PUNCT
fnp-3766	488	4	jr	jr	PROPN
fnp-3766	488	5	.	.	PROPN
fnp-3766	488	6	,	,	PUNCT
fnp-3766	488	7	lowe	lowe	PROPN
fnp-3766	488	8	vj	vj	PROPN
fnp-3766	488	9	,	,	PUNCT
fnp-3766	488	10	weigand	weigand	PROPN
fnp-3766	488	11	sd	sd	NOUN
fnp-3766	488	12	,	,	PUNCT
fnp-3766	488	13	wiste	wiste	PROPN
fnp-3766	488	14	hj	hj	PROPN
fnp-3766	488	15	,	,	PUNCT
fnp-3766	488	16	senjem	senjem	NOUN
fnp-3766	488	17	ml	ml	ADP
fnp-3766	488	18	,	,	PUNCT
fnp-3766	488	19	knopman	knopman	NOUN
fnp-3766	488	20	ds	ds	PROPN
fnp-3766	488	21	,	,	PUNCT
fnp-3766	488	22	et	et	PROPN
fnp-3766	488	23	al	al	PROPN
fnp-3766	488	24	.	.	PROPN
fnp-3766	488	25	serial	serial	PROPN
fnp-3766	488	26	pib	pib	PROPN
fnp-3766	488	27	and	and	CCONJ
fnp-3766	488	28	mri	mri	NOUN
fnp-3766	488	29	in	in	ADP
fnp-3766	488	30	normal	normal	ADJ
fnp-3766	488	31	,	,	PUNCT
fnp-3766	488	32	mild	mild	ADJ
fnp-3766	488	33	cognitive	cognitive	ADJ
fnp-3766	488	34	impairment	impairment	NOUN
fnp-3766	488	35	and	and	CCONJ
fnp-3766	488	36	alzheimer	alzheimer	NOUN
fnp-3766	488	37	's	's	PART
fnp-3766	488	38	disease	disease	NOUN
fnp-3766	488	39	:	:	PUNCT
fnp-3766	488	40	implications	implication	NOUN
fnp-3766	488	41	for	for	ADP
fnp-3766	488	42	sequence	sequence	NOUN
fnp-3766	488	43	of	of	ADP
fnp-3766	488	44	pathological	pathological	ADJ
fnp-3766	488	45	events	event	NOUN
fnp-3766	488	46	in	in	ADP
fnp-3766	488	47	alzheimer	alzheimer	PROPN
fnp-3766	488	48	's	's	PART
fnp-3766	488	49	disease	disease	NOUN
fnp-3766	488	50	.	.	PUNCT
fnp-3766	489	1	brain	brain	NOUN
fnp-3766	489	2	.	.	PUNCT
fnp-3766	490	1	2009;132(pt	2009;132(pt	NUM
fnp-3766	490	2	5):1355	5):1355	NUM
fnp-3766	490	3	-	-	PUNCT
fnp-3766	490	4	65	65	NUM
fnp-3766	490	5	.	.	PUNCT
fnp-3766	491	1	25	25	NUM
fnp-3766	491	2	.	.	PUNCT
fnp-3766	492	1	moore	moore	PROPN
fnp-3766	492	2	bd	bd	PROPN
fnp-3766	492	3	,	,	PUNCT
fnp-3766	492	4	chakrabarty	chakrabarty	PROPN
fnp-3766	492	5	p	p	X
fnp-3766	492	6	,	,	PUNCT
fnp-3766	492	7	levites	levites	PROPN
fnp-3766	492	8	y	y	PROPN
fnp-3766	492	9	,	,	PUNCT
fnp-3766	492	10	kukar	kukar	PROPN
fnp-3766	492	11	tl	tl	PROPN
fnp-3766	492	12	,	,	PUNCT
fnp-3766	492	13	baine	baine	PROPN
fnp-3766	492	14	am	am	PROPN
fnp-3766	492	15	,	,	PUNCT
fnp-3766	492	16	moroni	moroni	PROPN
fnp-3766	492	17	t	t	PROPN
fnp-3766	492	18	,	,	PUNCT
fnp-3766	492	19	et	et	PROPN
fnp-3766	492	20	al	al	PROPN
fnp-3766	492	21	.	.	PUNCT
fnp-3766	492	22	overlapping	overlap	VERB
fnp-3766	492	23	profiles	profile	NOUN
fnp-3766	492	24	of	of	ADP
fnp-3766	492	25	abeta	abeta	NOUN
fnp-3766	492	26	peptides	peptide	NOUN
fnp-3766	492	27	in	in	ADP
fnp-3766	492	28	the	the	DET
fnp-3766	492	29	alzheimer	alzheimer	NOUN
fnp-3766	492	30	's	's	PART
fnp-3766	492	31	disease	disease	NOUN
fnp-3766	492	32	and	and	CCONJ
fnp-3766	492	33	pathological	pathological	ADJ
fnp-3766	492	34	aging	age	VERB
fnp-3766	492	35	brains	brain	NOUN
fnp-3766	492	36	.	.	PUNCT
fnp-3766	493	1	alzheimers	alzheimer	NOUN
fnp-3766	493	2	res	re	VERB
fnp-3766	493	3	ther	ther	ADV
fnp-3766	493	4	.	.	PUNCT
fnp-3766	494	1	2012;4(3):18	2012;4(3):18	X
fnp-3766	494	2	.	.	NOUN
fnp-3766	494	3	26	26	NUM
fnp-3766	494	4	.	.	PUNCT
fnp-3766	495	1	dickson	dickson	PROPN
fnp-3766	495	2	dw	dw	PROPN
fnp-3766	495	3	,	,	PUNCT
fnp-3766	495	4	crystal	crystal	PROPN
fnp-3766	495	5	ha	ha	INTJ
fnp-3766	495	6	,	,	PUNCT
fnp-3766	495	7	mattiace	mattiace	PROPN
fnp-3766	495	8	la	la	PROPN
fnp-3766	495	9	,	,	PUNCT
fnp-3766	495	10	masur	masur	PROPN
fnp-3766	495	11	dm	dm	PROPN
fnp-3766	495	12	,	,	PUNCT
fnp-3766	495	13	blau	blau	NOUN
fnp-3766	495	14	ad	ad	NOUN
fnp-3766	495	15	,	,	PUNCT
fnp-3766	495	16	davies	davy	NOUN
fnp-3766	495	17	p	p	X
fnp-3766	495	18	,	,	PUNCT
fnp-3766	495	19	et	et	PROPN
fnp-3766	495	20	al	al	PROPN
fnp-3766	495	21	.	.	PUNCT
fnp-3766	496	1	identification	identification	NOUN
fnp-3766	496	2	of	of	ADP
fnp-3766	496	3	normal	normal	ADJ
fnp-3766	496	4	and	and	CCONJ
fnp-3766	496	5	pathological	pathological	ADJ
fnp-3766	496	6	aging	aging	NOUN
fnp-3766	496	7	in	in	ADP
fnp-3766	496	8	prospectively	prospectively	ADV
fnp-3766	496	9	studied	study	VERB
fnp-3766	496	10	nondemented	nondemente	VERB
fnp-3766	496	11	elderly	elderly	ADJ
fnp-3766	496	12	humans	human	NOUN
fnp-3766	496	13	.	.	PUNCT
fnp-3766	497	1	neurobiol	neurobiol	PROPN
fnp-3766	497	2	aging	aging	NOUN
fnp-3766	497	3	.	.	PUNCT
fnp-3766	498	1	1992;13(1):179	1992;13(1):179	NUM
fnp-3766	498	2	-	-	SYM
fnp-3766	498	3	89	89	NUM
fnp-3766	498	4	.	.	PUNCT
fnp-3766	498	5	27	27	NUM
fnp-3766	498	6	.	.	PUNCT
fnp-3766	499	1	dickson	dickson	PROPN
fnp-3766	499	2	dw	dw	PROPN
fnp-3766	499	3	,	,	PUNCT
fnp-3766	499	4	crystal	crystal	PROPN
fnp-3766	499	5	ha	ha	INTJ
fnp-3766	499	6	,	,	PUNCT
fnp-3766	499	7	bevona	bevona	PROPN
fnp-3766	499	8	c	c	PROPN
fnp-3766	499	9	,	,	PUNCT
fnp-3766	499	10	honer	honer	PROPN
fnp-3766	499	11	w	w	PROPN
fnp-3766	499	12	,	,	PUNCT
fnp-3766	499	13	vincent	vincent	PROPN
fnp-3766	499	14	i	i	PROPN
fnp-3766	499	15	,	,	PUNCT
fnp-3766	499	16	davies	davy	NOUN
fnp-3766	499	17	p.	p.	NOUN
fnp-3766	499	18	correlations	correlation	NOUN
fnp-3766	499	19	of	of	ADP
fnp-3766	499	20	synaptic	synaptic	ADJ
fnp-3766	499	21	and	and	CCONJ
fnp-3766	499	22	pathological	pathological	ADJ
fnp-3766	499	23	markers	marker	NOUN
fnp-3766	499	24	with	with	ADP
fnp-3766	499	25	cognition	cognition	NOUN
fnp-3766	499	26	of	of	ADP
fnp-3766	499	27	the	the	DET
fnp-3766	499	28	elderly	elderly	ADJ
fnp-3766	499	29	.	.	PUNCT
fnp-3766	500	1	neurobiol	neurobiol	PROPN
fnp-3766	500	2	aging	aging	NOUN
fnp-3766	500	3	.	.	PUNCT
fnp-3766	501	1	1995;16(3):285	1995;16(3):285	NUM
fnp-3766	501	2	-	-	SYM
fnp-3766	501	3	98	98	NUM
fnp-3766	501	4	;	;	PUNCT
fnp-3766	501	5	discussion	discussion	NOUN
fnp-3766	501	6	98	98	NUM
fnp-3766	501	7	-	-	SYM
fnp-3766	501	8	304	304	NUM
fnp-3766	501	9	.	.	PUNCT
fnp-3766	501	10	28	28	NUM
fnp-3766	501	11	.	.	PUNCT
fnp-3766	502	1	golde	golde	PROPN
fnp-3766	502	2	te	te	PROPN
fnp-3766	502	3	,	,	PUNCT
fnp-3766	502	4	dickson	dickson	PROPN
fnp-3766	502	5	d	d	PROPN
fnp-3766	502	6	,	,	PUNCT
fnp-3766	502	7	hutton	hutton	PROPN
fnp-3766	502	8	m.	m.	NOUN
fnp-3766	502	9	filling	fill	VERB
fnp-3766	502	10	the	the	DET
fnp-3766	502	11	gaps	gap	NOUN
fnp-3766	502	12	in	in	ADP
fnp-3766	502	13	the	the	DET
fnp-3766	502	14	abeta	abeta	NOUN
fnp-3766	502	15	cascade	cascade	NOUN
fnp-3766	502	16	hypothesis	hypothesis	NOUN
fnp-3766	502	17	of	of	ADP
fnp-3766	502	18	alzheimer	alzheimer	PROPN
fnp-3766	502	19	's	's	PART
fnp-3766	502	20	disease	disease	NOUN
fnp-3766	502	21	.	.	PUNCT
fnp-3766	503	1	curr	curr	PROPN
fnp-3766	503	2	alzheimer	alzheimer	PROPN
fnp-3766	503	3	res	res	PROPN
fnp-3766	503	4	.	.	PUNCT
fnp-3766	504	1	2006;3(5):421	2006;3(5):421	NUM
fnp-3766	504	2	-	-	SYM
fnp-3766	504	3	30	30	NUM
fnp-3766	504	4	.	.	PUNCT
fnp-3766	505	1	29	29	NUM
fnp-3766	505	2	.	.	PUNCT
fnp-3766	506	1	ayers	ayers	PROPN
fnp-3766	506	2	ji	ji	PROPN
fnp-3766	506	3	,	,	PUNCT
fnp-3766	506	4	fromholt	fromholt	PROPN
fnp-3766	506	5	s	s	PART
fnp-3766	506	6	,	,	PUNCT
fnp-3766	506	7	sinyavskaya	sinyavskaya	NOUN
fnp-3766	506	8	o	o	PROPN
fnp-3766	506	9	,	,	PUNCT
fnp-3766	506	10	siemienski	siemienski	PROPN
fnp-3766	506	11	z	z	PROPN
fnp-3766	506	12	,	,	PUNCT
fnp-3766	506	13	rosario	rosario	PROPN
fnp-3766	506	14	am	be	AUX
fnp-3766	506	15	,	,	PUNCT
fnp-3766	506	16	li	li	PROPN
fnp-3766	506	17	a	a	PROPN
fnp-3766	506	18	,	,	PUNCT
fnp-3766	506	19	et	et	PROPN
fnp-3766	506	20	al	al	PROPN
fnp-3766	506	21	.	.	PROPN
fnp-3766	506	22	widespread	widespread	ADJ
fnp-3766	506	23	and	and	CCONJ
fnp-3766	506	24	efficient	efficient	ADJ
fnp-3766	506	25	transduction	transduction	NOUN
fnp-3766	506	26	of	of	ADP
fnp-3766	506	27	spinal	spinal	ADJ
fnp-3766	506	28	cord	cord	NOUN
fnp-3766	506	29	and	and	CCONJ
fnp-3766	506	30	brain	brain	NOUN
fnp-3766	506	31	following	follow	VERB
fnp-3766	506	32	neonatal	neonatal	ADJ
fnp-3766	506	33	aav	aav	NOUN
fnp-3766	506	34	injection	injection	NOUN
fnp-3766	506	35	and	and	CCONJ
fnp-3766	506	36	potential	potential	ADJ
fnp-3766	506	37	disease	disease	NOUN
fnp-3766	506	38	modifying	modify	VERB
fnp-3766	506	39	effect	effect	NOUN
fnp-3766	506	40	in	in	ADP
fnp-3766	506	41	als	als	NOUN
fnp-3766	506	42	mice	mouse	NOUN
fnp-3766	506	43	.	.	PUNCT
fnp-3766	507	1	mol	mol	ADP
fnp-3766	507	2	ther	ther	ADV
fnp-3766	507	3	.	.	PUNCT
fnp-3766	508	1	2015;23(1):53	2015;23(1):53	NUM
fnp-3766	508	2	-	-	SYM
fnp-3766	508	3	62	62	NUM
fnp-3766	508	4	.	.	PUNCT
fnp-3766	509	1	30	30	NUM
fnp-3766	509	2	.	.	PUNCT
fnp-3766	510	1	kim	kim	PROPN
fnp-3766	510	2	jy	jy	PROPN
fnp-3766	510	3	,	,	PUNCT
fnp-3766	510	4	grunke	grunke	VERB
fnp-3766	510	5	sd	sd	NOUN
fnp-3766	510	6	,	,	PUNCT
fnp-3766	510	7	levites	levites	PROPN
fnp-3766	510	8	y	y	PROPN
fnp-3766	510	9	,	,	PUNCT
fnp-3766	510	10	golde	golde	PROPN
fnp-3766	510	11	te	te	PROPN
fnp-3766	510	12	,	,	PUNCT
fnp-3766	510	13	jankowsky	jankowsky	PROPN
fnp-3766	510	14	jl	jl	PROPN
fnp-3766	510	15	.	.	PUNCT
fnp-3766	511	1	intracerebroventricular	intracerebroventricular	ADJ
fnp-3766	511	2	viral	viral	ADJ
fnp-3766	511	3	injection	injection	NOUN
fnp-3766	511	4	of	of	ADP
fnp-3766	511	5	the	the	DET
fnp-3766	511	6	neonatal	neonatal	ADJ
fnp-3766	511	7	mouse	mouse	NOUN
fnp-3766	511	8	brain	brain	NOUN
fnp-3766	511	9	for	for	ADP
fnp-3766	511	10	persistent	persistent	ADJ
fnp-3766	511	11	and	and	CCONJ
fnp-3766	511	12	widespread	widespread	ADJ
fnp-3766	511	13	neuronal	neuronal	ADJ
fnp-3766	511	14	transduction	transduction	NOUN
fnp-3766	511	15	.	.	PUNCT
fnp-3766	512	1	j	j	PROPN
fnp-3766	512	2	vis	vis	X
fnp-3766	512	3	exp	exp	PROPN
fnp-3766	512	4	.	.	PUNCT
fnp-3766	512	5	2014(91):51863	2014(91):51863	NUM
fnp-3766	512	6	.	.	PUNCT
fnp-3766	513	1	31	31	NUM
fnp-3766	513	2	.	.	PUNCT
fnp-3766	514	1	dhillon	dhillon	PROPN
fnp-3766	514	2	js	js	PROPN
fnp-3766	514	3	,	,	PUNCT
fnp-3766	514	4	trejo	trejo	PROPN
fnp-3766	514	5	-	-	PUNCT
fnp-3766	514	6	lopez	lopez	PROPN
fnp-3766	514	7	ja	ja	PROPN
fnp-3766	514	8	,	,	PUNCT
fnp-3766	514	9	riffe	riffe	PROPN
fnp-3766	514	10	c	c	PROPN
fnp-3766	514	11	,	,	PUNCT
fnp-3766	514	12	levites	levites	PROPN
fnp-3766	514	13	y	y	PROPN
fnp-3766	514	14	,	,	PUNCT
fnp-3766	514	15	sacino	sacino	PROPN
fnp-3766	514	16	an	an	PRON
fnp-3766	514	17	,	,	PUNCT
fnp-3766	514	18	borchelt	borchelt	PROPN
fnp-3766	514	19	dr	dr	PROPN
fnp-3766	514	20	,	,	PUNCT
fnp-3766	514	21	et	et	PROPN
fnp-3766	514	22	al	al	PROPN
fnp-3766	514	23	.	.	PROPN
fnp-3766	515	1	comparative	comparative	ADJ
fnp-3766	515	2	analyses	analysis	NOUN
fnp-3766	515	3	of	of	ADP
fnp-3766	515	4	the	the	PRON
fnp-3766	515	5	in	in	ADP
fnp-3766	515	6	vivo	vivo	ADJ
fnp-3766	515	7	induction	induction	NOUN
fnp-3766	515	8	and	and	CCONJ
fnp-3766	515	9	transmission	transmission	NOUN
fnp-3766	515	10	of	of	ADP
fnp-3766	515	11	alpha	alpha	NOUN
fnp-3766	515	12	-	-	PUNCT
fnp-3766	515	13	synuclein	synuclein	NOUN
fnp-3766	515	14	pathology	pathology	NOUN
fnp-3766	515	15	in	in	ADP
fnp-3766	515	16	transgenic	transgenic	NOUN
fnp-3766	515	17	mice	mouse	NOUN
fnp-3766	515	18	by	by	ADP
fnp-3766	515	19	msa	msa	PROPN
fnp-3766	515	20	brain	brain	NOUN
fnp-3766	515	21	lysate	lysate	NOUN
fnp-3766	515	22	and	and	CCONJ
fnp-3766	515	23	recombinant	recombinant	ADJ
fnp-3766	515	24	alpha	alpha	NOUN
fnp-3766	515	25	-	-	PUNCT
fnp-3766	515	26	synuclein	synuclein	NOUN
fnp-3766	515	27	fibrils	fibril	NOUN
fnp-3766	515	28	.	.	PUNCT
fnp-3766	516	1	acta	acta	PROPN
fnp-3766	516	2	neuropathol	neuropathol	PROPN
fnp-3766	516	3	commun	commun	PROPN
fnp-3766	516	4	.	.	PUNCT
fnp-3766	517	1	2019;7(1):80	2019;7(1):80	NUM
fnp-3766	517	2	.	.	PROPN
fnp-3766	517	3	32	32	NUM
fnp-3766	517	4	.	.	PUNCT
fnp-3766	518	1	saido	saido	PROPN
fnp-3766	518	2	tc	tc	PROPN
fnp-3766	518	3	,	,	PUNCT
fnp-3766	518	4	kawashima	kawashima	PROPN
fnp-3766	518	5	s	s	PROPN
fnp-3766	518	6	,	,	PUNCT
fnp-3766	518	7	tani	tani	ADJ
fnp-3766	518	8	e	e	NOUN
fnp-3766	518	9	,	,	PUNCT
fnp-3766	518	10	yokota	yokota	PROPN
fnp-3766	518	11	m.	m.	PROPN
fnp-3766	518	12	upand	upand	PROPN
fnp-3766	518	13	down	down	ADP
fnp-3766	518	14	-	-	PUNCT
fnp-3766	518	15	regulation	regulation	NOUN
fnp-3766	518	16	of	of	ADP
fnp-3766	518	17	calpain	calpain	NOUN
fnp-3766	518	18	inhibitor	inhibitor	NOUN
fnp-3766	518	19	polypeptide	polypeptide	NOUN
fnp-3766	518	20	,	,	PUNCT
fnp-3766	518	21	calpastatin	calpastatin	NOUN
fnp-3766	518	22	,	,	PUNCT
fnp-3766	518	23	in	in	ADP
fnp-3766	518	24	postischemic	postischemic	ADJ
fnp-3766	518	25	hippocampus	hippocampus	NOUN
fnp-3766	518	26	.	.	PUNCT
fnp-3766	519	1	neurosci	neurosci	PROPN
fnp-3766	519	2	lett	lett	PROPN
fnp-3766	519	3	.	.	PUNCT
fnp-3766	520	1	1997;227(2):75	1997;227(2):75	PROPN
fnp-3766	520	2	-	-	SYM
fnp-3766	520	3	8	8	NUM
fnp-3766	520	4	.	.	X
fnp-3766	520	5	33	33	NUM
fnp-3766	520	6	.	.	PUNCT
fnp-3766	521	1	schmidt	schmidt	PROPN
fnp-3766	521	2	ml	ml	PROPN
fnp-3766	521	3	,	,	PUNCT
fnp-3766	521	4	didario	didario	PROPN
fnp-3766	521	5	ag	ag	PROPN
fnp-3766	521	6	,	,	PUNCT
fnp-3766	521	7	otvos	otvos	NOUN
fnp-3766	521	8	l	l	NOUN
fnp-3766	521	9	,	,	PUNCT
fnp-3766	521	10	jr	jr	PROPN
fnp-3766	521	11	.	.	PROPN
fnp-3766	521	12	,	,	PUNCT
fnp-3766	521	13	hoshi	hoshi	PROPN
fnp-3766	521	14	n	n	PROPN
fnp-3766	521	15	,	,	PUNCT
fnp-3766	521	16	kant	kant	PROPN
fnp-3766	521	17	ja	ja	PROPN
fnp-3766	521	18	,	,	PUNCT
fnp-3766	521	19	lee	lee	PROPN
fnp-3766	521	20	vm	vm	PROPN
fnp-3766	521	21	,	,	PUNCT
fnp-3766	521	22	et	et	PROPN
fnp-3766	521	23	al	al	PROPN
fnp-3766	521	24	.	.	PUNCT
fnp-3766	521	25	plaque	plaque	NOUN
fnp-3766	521	26	-	-	PUNCT
fnp-3766	521	27	associated	associate	VERB
fnp-3766	521	28	neuronal	neuronal	ADJ
fnp-3766	521	29	proteins	protein	NOUN
fnp-3766	521	30	:	:	PUNCT
fnp-3766	521	31	a	a	DET
fnp-3766	521	32	recurrent	recurrent	ADJ
fnp-3766	521	33	motif	motif	NOUN
fnp-3766	521	34	in	in	ADP
fnp-3766	521	35	neuritic	neuritic	ADJ
fnp-3766	521	36	amyloid	amyloid	NOUN
fnp-3766	521	37	deposits	deposit	NOUN
fnp-3766	521	38	throughout	throughout	ADP
fnp-3766	521	39	diverse	diverse	ADJ
fnp-3766	521	40	cortical	cortical	ADJ
fnp-3766	521	41	areas	area	NOUN
fnp-3766	521	42	of	of	ADP
fnp-3766	521	43	the	the	DET
fnp-3766	521	44	alzheimer	alzheimer	PROPN
fnp-3766	521	45	's	's	PART
fnp-3766	521	46	disease	disease	NOUN
fnp-3766	521	47	brain	brain	NOUN
fnp-3766	521	48	.	.	PUNCT
fnp-3766	522	1	exp	exp	NOUN
fnp-3766	522	2	neurol	neurol	NOUN
fnp-3766	522	3	.	.	PUNCT
fnp-3766	523	1	1994;130(2):311	1994;130(2):311	NUM
fnp-3766	523	2	-	-	SYM
fnp-3766	523	3	22	22	NUM
fnp-3766	523	4	.	.	PUNCT
fnp-3766	524	1	34	34	NUM
fnp-3766	524	2	.	.	PUNCT
fnp-3766	525	1	mckeith	mckeith	PROPN
fnp-3766	525	2	ig	ig	PROPN
fnp-3766	525	3	,	,	PUNCT
fnp-3766	525	4	boeve	boeve	NOUN
fnp-3766	525	5	bf	bf	NOUN
fnp-3766	525	6	,	,	PUNCT
fnp-3766	525	7	dickson	dickson	PROPN
fnp-3766	525	8	dw	dw	PROPN
fnp-3766	525	9	,	,	PUNCT
fnp-3766	525	10	halliday	halliday	PROPN
fnp-3766	525	11	g	g	PROPN
fnp-3766	525	12	,	,	PUNCT
fnp-3766	525	13	taylor	taylor	PROPN
fnp-3766	525	14	jp	jp	PROPN
fnp-3766	525	15	,	,	PUNCT
fnp-3766	525	16	weintraub	weintraub	PROPN
fnp-3766	525	17	d	d	PROPN
fnp-3766	525	18	,	,	PUNCT
fnp-3766	525	19	et	et	PROPN
fnp-3766	525	20	al	al	PROPN
fnp-3766	525	21	.	.	PUNCT
fnp-3766	525	22	diagnosis	diagnosis	NOUN
fnp-3766	525	23	and	and	CCONJ
fnp-3766	525	24	management	management	NOUN
fnp-3766	525	25	of	of	ADP
fnp-3766	525	26	dementia	dementia	NOUN
fnp-3766	525	27	with	with	ADP
fnp-3766	525	28	lewy	lewy	PROPN
fnp-3766	525	29	bodies	body	NOUN
fnp-3766	525	30	:	:	PUNCT
fnp-3766	525	31	fourth	fourth	ADJ
fnp-3766	525	32	consensus	consensus	NOUN
fnp-3766	525	33	report	report	NOUN
fnp-3766	525	34	of	of	ADP
fnp-3766	525	35	the	the	DET
fnp-3766	525	36	dlb	dlb	PROPN
fnp-3766	525	37	consortium	consortium	PROPN
fnp-3766	525	38	.	.	PUNCT
fnp-3766	526	1	neurology	neurology	NOUN
fnp-3766	526	2	.	.	PUNCT
fnp-3766	527	1	2017;89(1):88	2017;89(1):88	NUM
fnp-3766	527	2	-	-	SYM
fnp-3766	527	3	100	100	NUM
fnp-3766	527	4	.	.	X
fnp-3766	528	1	35	35	NUM
fnp-3766	528	2	.	.	PUNCT
fnp-3766	528	3	montine	montine	PROPN
fnp-3766	528	4	tj	tj	PROPN
fnp-3766	528	5	,	,	PUNCT
fnp-3766	528	6	phelps	phelps	PROPN
fnp-3766	528	7	ch	ch	PROPN
fnp-3766	528	8	,	,	PUNCT
fnp-3766	528	9	beach	beach	PROPN
fnp-3766	528	10	tg	tg	PROPN
fnp-3766	528	11	,	,	PUNCT
fnp-3766	528	12	bigio	bigio	NOUN
fnp-3766	528	13	eh	eh	INTJ
fnp-3766	528	14	,	,	PUNCT
fnp-3766	528	15	cairns	cairns	PROPN
fnp-3766	528	16	nj	nj	PROPN
fnp-3766	528	17	,	,	PUNCT
fnp-3766	528	18	dickson	dickson	PROPN
fnp-3766	528	19	dw	dw	PROPN
fnp-3766	528	20	,	,	PUNCT
fnp-3766	528	21	et	et	PROPN
fnp-3766	528	22	al	al	PROPN
fnp-3766	528	23	.	.	PROPN
fnp-3766	529	1	national	national	PROPN
fnp-3766	529	2	institute	institute	PROPN
fnp-3766	529	3	on	on	ADP
fnp-3766	529	4	aging	age	VERB
fnp-3766	529	5	-	-	PUNCT
fnp-3766	529	6	alzheimer	alzheimer	NOUN
fnp-3766	529	7	's	's	PART
fnp-3766	529	8	association	association	NOUN
fnp-3766	529	9	guidelines	guideline	NOUN
fnp-3766	529	10	for	for	ADP
fnp-3766	529	11	the	the	DET
fnp-3766	529	12	neuropathologic	neuropathologic	ADJ
fnp-3766	529	13	assessment	assessment	NOUN
fnp-3766	529	14	of	of	ADP
fnp-3766	529	15	alzheimer	alzheimer	PROPN
fnp-3766	529	16	's	's	PART
fnp-3766	529	17	disease	disease	NOUN
fnp-3766	529	18	:	:	PUNCT
fnp-3766	529	19	a	a	DET
fnp-3766	529	20	practical	practical	ADJ
fnp-3766	529	21	approach	approach	NOUN
fnp-3766	529	22	.	.	PUNCT
fnp-3766	530	1	acta	acta	PROPN
fnp-3766	530	2	neuropathol	neuropathol	PROPN
fnp-3766	530	3	.	.	PUNCT
fnp-3766	531	1	2012;123(1):1	2012;123(1):1	NUM
fnp-3766	531	2	-	-	SYM
fnp-3766	531	3	11	11	NUM
fnp-3766	531	4	.	.	PUNCT
fnp-3766	532	1	36	36	NUM
fnp-3766	532	2	.	.	PUNCT
fnp-3766	533	1	charidimou	charidimou	PROPN
fnp-3766	533	2	a	a	PRON
fnp-3766	533	3	,	,	PUNCT
fnp-3766	533	4	martinez	martinez	PROPN
fnp-3766	533	5	-	-	PROPN
fnp-3766	533	6	ramirez	ramirez	PROPN
fnp-3766	533	7	s	s	PART
fnp-3766	533	8	,	,	PUNCT
fnp-3766	533	9	shoamanesh	shoamanesh	NOUN
fnp-3766	533	10	a	a	PRON
fnp-3766	533	11	,	,	PUNCT
fnp-3766	533	12	oliveira	oliveira	PROPN
fnp-3766	533	13	-	-	PUNCT
fnp-3766	533	14	filho	filho	PROPN
fnp-3766	533	15	j	j	PROPN
fnp-3766	533	16	,	,	PUNCT
fnp-3766	533	17	frosch	frosch	PROPN
fnp-3766	533	18	m	m	PROPN
fnp-3766	533	19	,	,	PUNCT
fnp-3766	533	20	vashkevich	vashkevich	VERB
fnp-3766	533	21	a	a	DET
fnp-3766	533	22	,	,	PUNCT
fnp-3766	533	23	et	et	PROPN
fnp-3766	533	24	al	al	PROPN
fnp-3766	533	25	.	.	PROPN
fnp-3766	533	26	cerebral	cerebral	ADJ
fnp-3766	533	27	amyloid	amyloid	NOUN
fnp-3766	533	28	angiopathy	angiopathy	NOUN
fnp-3766	533	29	with	with	ADP
fnp-3766	533	30	and	and	CCONJ
fnp-3766	533	31	without	without	ADP
fnp-3766	533	32	hemorrhage	hemorrhage	NOUN
fnp-3766	533	33	:	:	PUNCT
fnp-3766	533	34	evidence	evidence	NOUN
fnp-3766	533	35	for	for	ADP
fnp-3766	533	36	different	different	ADJ
fnp-3766	533	37	disease	disease	NOUN
fnp-3766	533	38	phenotypes	phenotype	NOUN
fnp-3766	533	39	.	.	PUNCT
fnp-3766	534	1	neurology	neurology	NOUN
fnp-3766	534	2	.	.	PUNCT
fnp-3766	535	1	2015;84(12):1206	2015;84(12):1206	NUM
fnp-3766	535	2	-	-	SYM
fnp-3766	535	3	12	12	NUM
fnp-3766	535	4	.	.	PUNCT
fnp-3766	536	1	37	37	NUM
fnp-3766	536	2	.	.	PUNCT
fnp-3766	537	1	xu	xu	PROPN
fnp-3766	537	2	g	g	PROPN
fnp-3766	537	3	,	,	PUNCT
fnp-3766	537	4	ran	run	VERB
fnp-3766	537	5	y	y	PROPN
fnp-3766	537	6	,	,	PUNCT
fnp-3766	537	7	fromholt	fromholt	NOUN
fnp-3766	537	8	se	se	PROPN
fnp-3766	537	9	,	,	PUNCT
fnp-3766	537	10	fu	fu	PROPN
fnp-3766	537	11	c	c	PROPN
fnp-3766	537	12	,	,	PUNCT
fnp-3766	537	13	yachnis	yachnis	X
fnp-3766	537	14	at	at	ADP
fnp-3766	537	15	,	,	PUNCT
fnp-3766	537	16	golde	golde	PROPN
fnp-3766	537	17	te	te	PROPN
fnp-3766	537	18	,	,	PUNCT
fnp-3766	537	19	et	et	PROPN
fnp-3766	537	20	al	al	PROPN
fnp-3766	537	21	.	.	PROPN
fnp-3766	537	22	murine	murine	PROPN
fnp-3766	537	23	abeta	abeta	PROPN
fnp-3766	537	24	over	over	ADP
fnp-3766	537	25	-	-	PUNCT
fnp-3766	537	26	production	production	NOUN
fnp-3766	537	27	produces	produce	VERB
fnp-3766	537	28	diffuse	diffuse	NOUN
fnp-3766	537	29	and	and	CCONJ
fnp-3766	537	30	compact	compact	ADJ
fnp-3766	537	31	alzheimer	alzheimer	ADJ
fnp-3766	537	32	-	-	PUNCT
fnp-3766	537	33	type	type	NOUN
fnp-3766	537	34	amyloid	amyloid	NOUN
fnp-3766	537	35	deposits	deposit	NOUN
fnp-3766	537	36	.	.	PUNCT
fnp-3766	538	1	acta	acta	PROPN
fnp-3766	538	2	neuropathol	neuropathol	PROPN
fnp-3766	538	3	commun	commun	PROPN
fnp-3766	538	4	.	.	PUNCT
fnp-3766	539	1	2015;3:72	2015;3:72	PROPN
fnp-3766	539	2	.	.	PUNCT
fnp-3766	540	1	38	38	NUM
fnp-3766	540	2	.	.	PUNCT
fnp-3766	541	1	santacruz	santacruz	PROPN
fnp-3766	541	2	k	k	PROPN
fnp-3766	541	3	,	,	PUNCT
fnp-3766	541	4	lewis	lewis	PROPN
fnp-3766	541	5	j	j	PROPN
fnp-3766	541	6	,	,	PUNCT
fnp-3766	541	7	spires	spires	PROPN
fnp-3766	541	8	t	t	PROPN
fnp-3766	541	9	,	,	PUNCT
fnp-3766	541	10	paulson	paulson	PROPN
fnp-3766	541	11	j	j	PROPN
fnp-3766	541	12	,	,	PUNCT
fnp-3766	541	13	kotilinek	kotilinek	PROPN
fnp-3766	541	14	l	l	NOUN
fnp-3766	541	15	,	,	PUNCT
fnp-3766	541	16	ingelsson	ingelsson	PROPN
fnp-3766	541	17	m	m	PROPN
fnp-3766	541	18	,	,	PUNCT
fnp-3766	541	19	et	et	PROPN
fnp-3766	541	20	al	al	PROPN
fnp-3766	541	21	.	.	PUNCT
fnp-3766	542	1	tau	tau	PROPN
fnp-3766	542	2	suppression	suppression	NOUN
fnp-3766	542	3	in	in	ADP
fnp-3766	542	4	a	a	DET
fnp-3766	542	5	neurodegenerative	neurodegenerative	ADJ
fnp-3766	542	6	mouse	mouse	NOUN
fnp-3766	542	7	model	model	NOUN
fnp-3766	542	8	improves	improve	VERB
fnp-3766	542	9	memory	memory	NOUN
fnp-3766	542	10	function	function	NOUN
fnp-3766	542	11	.	.	PUNCT
fnp-3766	543	1	science	science	NOUN
fnp-3766	543	2	.	.	PUNCT
fnp-3766	544	1	2005;309(5733):476	2005;309(5733):476	NUM
fnp-3766	544	2	-	-	SYM
fnp-3766	544	3	81	81	NUM
fnp-3766	544	4	.	.	NOUN
fnp-3766	544	5	39	39	NUM
fnp-3766	544	6	.	.	PUNCT
fnp-3766	545	1	strang	strang	PROPN
fnp-3766	545	2	kh	kh	PROPN
fnp-3766	545	3	,	,	PUNCT
fnp-3766	545	4	goodwin	goodwin	PROPN
fnp-3766	545	5	ms	ms	PROPN
fnp-3766	545	6	,	,	PUNCT
fnp-3766	545	7	riffe	riffe	PROPN
fnp-3766	545	8	c	c	PROPN
fnp-3766	545	9	,	,	PUNCT
fnp-3766	545	10	moore	moore	PROPN
fnp-3766	545	11	bd	bd	PROPN
fnp-3766	545	12	,	,	PUNCT
fnp-3766	545	13	chakrabarty	chakrabarty	PROPN
fnp-3766	545	14	p	p	X
fnp-3766	545	15	,	,	PUNCT
fnp-3766	545	16	levites	levites	PROPN
fnp-3766	545	17	y	y	PROPN
fnp-3766	545	18	,	,	PUNCT
fnp-3766	545	19	et	et	PROPN
fnp-3766	545	20	al	al	PROPN
fnp-3766	545	21	.	.	PUNCT
fnp-3766	545	22	generation	generation	NOUN
fnp-3766	545	23	and	and	CCONJ
fnp-3766	545	24	characterization	characterization	NOUN
fnp-3766	545	25	of	of	ADP
fnp-3766	545	26	new	new	ADJ
fnp-3766	545	27	monoclonal	monoclonal	NOUN
fnp-3766	545	28	antibodies	antibody	NOUN
fnp-3766	545	29	targeting	target	VERB
fnp-3766	545	30	the	the	DET
fnp-3766	545	31	phf1	phf1	NOUN
fnp-3766	545	32	and	and	CCONJ
fnp-3766	545	33	at8	at8	PROPN
fnp-3766	545	34	epitopes	epitope	NOUN
fnp-3766	545	35	on	on	ADP
fnp-3766	545	36	human	human	PROPN
fnp-3766	545	37	tau	tau	PROPN
fnp-3766	545	38	.	.	PUNCT
fnp-3766	546	1	acta	acta	PROPN
fnp-3766	546	2	neuropathol	neuropathol	PROPN
fnp-3766	546	3	commun	commun	PROPN
fnp-3766	546	4	.	.	PUNCT
fnp-3766	547	1	2017;5(1):58	2017;5(1):58	NUM
fnp-3766	547	2	.	.	NOUN
fnp-3766	547	3	40	40	NUM
fnp-3766	547	4	.	.	PUNCT
fnp-3766	548	1	xia	xia	PROPN
fnp-3766	548	2	y	y	PROPN
fnp-3766	548	3	,	,	PUNCT
fnp-3766	548	4	bell	bell	PROPN
fnp-3766	548	5	bm	bm	PROPN
fnp-3766	548	6	,	,	PUNCT
fnp-3766	548	7	giasson	giasson	PROPN
fnp-3766	548	8	bi	bi	PROPN
fnp-3766	548	9	.	.	PROPN
fnp-3766	549	1	tau	tau	PROPN
fnp-3766	549	2	k321	k321	PROPN
fnp-3766	549	3	/	/	SYM
fnp-3766	549	4	k353	k353	PROPN
fnp-3766	549	5	pseudoacetylation	pseudoacetylation	NOUN
fnp-3766	549	6	within	within	ADP
fnp-3766	549	7	kxgs	kxgs	PROPN
fnp-3766	549	8	motifs	motifs	PROPN
fnp-3766	549	9	regulates	regulate	VERB
fnp-3766	549	10	tau	tau	NOUN
fnp-3766	549	11	-	-	PUNCT
fnp-3766	549	12	microtubule	microtubule	NOUN
fnp-3766	549	13	interactions	interaction	NOUN
fnp-3766	549	14	and	and	CCONJ
fnp-3766	549	15	inhibits	inhibit	VERB
fnp-3766	549	16	aggregation	aggregation	NOUN
fnp-3766	549	17	.	.	PUNCT
fnp-3766	550	1	sci	sci	PROPN
fnp-3766	550	2	rep	rep	PROPN
fnp-3766	550	3	.	.	PROPN
fnp-3766	550	4	2021;11(1):17069	2021;11(1):17069	NUM
fnp-3766	550	5	.	.	PUNCT
fnp-3766	551	1	41	41	NUM
fnp-3766	551	2	.	.	PUNCT
fnp-3766	551	3	giasson	giasson	PROPN
fnp-3766	551	4	bi	bi	PROPN
fnp-3766	551	5	,	,	PUNCT
fnp-3766	551	6	duda	duda	PROPN
fnp-3766	551	7	je	je	PROPN
fnp-3766	551	8	,	,	PUNCT
fnp-3766	551	9	quinn	quinn	PROPN
fnp-3766	551	10	sm	sm	PROPN
fnp-3766	551	11	,	,	PUNCT
fnp-3766	551	12	zhang	zhang	PROPN
fnp-3766	551	13	b	b	PROPN
fnp-3766	551	14	,	,	PUNCT
fnp-3766	551	15	trojanowski	trojanowski	PROPN
fnp-3766	551	16	jq	jq	PROPN
fnp-3766	551	17	,	,	PUNCT
fnp-3766	551	18	lee	lee	PROPN
fnp-3766	551	19	vm	vm	PROPN
fnp-3766	551	20	.	.	PROPN
fnp-3766	551	21	neuronal	neuronal	ADJ
fnp-3766	551	22	alpha	alpha	NOUN
fnp-3766	551	23	-	-	PUNCT
fnp-3766	551	24	synucleinopathy	synucleinopathy	NOUN
fnp-3766	551	25	with	with	ADP
fnp-3766	551	26	severe	severe	ADJ
fnp-3766	551	27	movement	movement	NOUN
fnp-3766	551	28	disorder	disorder	NOUN
fnp-3766	551	29	in	in	ADP
fnp-3766	551	30	mice	mouse	NOUN
fnp-3766	551	31	expressing	express	VERB
fnp-3766	551	32	a53	a53	PROPN
fnp-3766	551	33	t	t	PROPN
fnp-3766	551	34	human	human	PROPN
fnp-3766	551	35	alpha	alpha	PROPN
fnp-3766	551	36	-	-	PUNCT
fnp-3766	551	37	synuclein	synuclein	NOUN
fnp-3766	551	38	.	.	PUNCT
fnp-3766	551	39	neuron	neuron	PROPN
fnp-3766	551	40	.	.	PUNCT
fnp-3766	552	1	2002;34(4):521	2002;34(4):521	NUM
fnp-3766	552	2	-	-	SYM
fnp-3766	552	3	33	33	NUM
fnp-3766	552	4	.	.	PUNCT
fnp-3766	552	5	42	42	NUM
fnp-3766	552	6	.	.	PUNCT
fnp-3766	553	1	meyer	meyer	PROPN
fnp-3766	553	2	-	-	PUNCT
fnp-3766	553	3	luehmann	luehmann	PROPN
fnp-3766	553	4	m	m	PROPN
fnp-3766	553	5	,	,	PUNCT
fnp-3766	553	6	coomaraswamy	coomaraswamy	PROPN
fnp-3766	553	7	j	j	NOUN
fnp-3766	553	8	,	,	PUNCT
fnp-3766	553	9	bolmont	bolmont	VERB
fnp-3766	553	10	t	t	PROPN
fnp-3766	553	11	,	,	PUNCT
fnp-3766	553	12	kaeser	kaeser	NOUN
fnp-3766	553	13	s	s	PROPN
fnp-3766	553	14	,	,	PUNCT
fnp-3766	553	15	schaefer	schaefer	PROPN
fnp-3766	553	16	c	c	PROPN
fnp-3766	553	17	,	,	PUNCT
fnp-3766	553	18	kilger	kilger	NOUN
fnp-3766	553	19	e	e	NOUN
fnp-3766	553	20	,	,	PUNCT
fnp-3766	553	21	et	et	PROPN
fnp-3766	553	22	al	al	PROPN
fnp-3766	553	23	.	.	PROPN
fnp-3766	554	1	exogenous	exogenous	ADJ
fnp-3766	554	2	induction	induction	NOUN
fnp-3766	554	3	of	of	ADP
fnp-3766	554	4	cerebral	cerebral	ADJ
fnp-3766	554	5	beta	beta	NOUN
fnp-3766	554	6	-	-	PUNCT
fnp-3766	554	7	amyloidogenesis	amyloidogenesis	NOUN
fnp-3766	554	8	is	be	AUX
fnp-3766	554	9	governed	govern	VERB
fnp-3766	554	10	by	by	ADP
fnp-3766	554	11	agent	agent	NOUN
fnp-3766	554	12	and	and	CCONJ
fnp-3766	554	13	host	host	NOUN
fnp-3766	554	14	.	.	PUNCT
fnp-3766	555	1	science	science	NOUN
fnp-3766	555	2	.	.	PUNCT
fnp-3766	556	1	2006;313(5794):1781	2006;313(5794):1781	NUM
fnp-3766	556	2	-	-	SYM
fnp-3766	556	3	4	4	NUM
fnp-3766	556	4	.	.	NUM
fnp-3766	556	5	43	43	NUM
fnp-3766	556	6	.	.	PUNCT
fnp-3766	557	1	chakrabarty	chakrabarty	PROPN
fnp-3766	557	2	p	p	X
fnp-3766	557	3	,	,	PUNCT
fnp-3766	557	4	rosario	rosario	PROPN
fnp-3766	557	5	a	a	PROPN
fnp-3766	557	6	,	,	PUNCT
fnp-3766	557	7	cruz	cruz	PROPN
fnp-3766	557	8	p	p	NOUN
fnp-3766	557	9	,	,	PUNCT
fnp-3766	557	10	siemienski	siemienski	PROPN
fnp-3766	557	11	z	z	PROPN
fnp-3766	557	12	,	,	PUNCT
fnp-3766	557	13	ceballos	ceballos	PROPN
fnp-3766	557	14	-	-	PUNCT
fnp-3766	557	15	diaz	diaz	PROPN
fnp-3766	557	16	c	c	PROPN
fnp-3766	557	17	,	,	PUNCT
fnp-3766	557	18	crosby	crosby	PROPN
fnp-3766	557	19	k	k	PROPN
fnp-3766	557	20	,	,	PUNCT
fnp-3766	557	21	et	et	PROPN
fnp-3766	557	22	al	al	PROPN
fnp-3766	557	23	.	.	PROPN
fnp-3766	557	24	capsid	capsid	PROPN
fnp-3766	557	25	serotype	serotype	NOUN
fnp-3766	557	26	and	and	CCONJ
fnp-3766	557	27	timing	timing	NOUN
fnp-3766	557	28	of	of	ADP
fnp-3766	557	29	injection	injection	NOUN
fnp-3766	557	30	determines	determine	VERB
fnp-3766	557	31	aav	aav	NOUN
fnp-3766	557	32	transduction	transduction	NOUN
fnp-3766	557	33	in	in	ADP
fnp-3766	557	34	the	the	DET
fnp-3766	557	35	neonatal	neonatal	ADJ
fnp-3766	557	36	mice	mouse	NOUN
fnp-3766	557	37	brain	brain	NOUN
fnp-3766	557	38	.	.	PUNCT
fnp-3766	558	1	plos	plos	PROPN
fnp-3766	558	2	one	one	NUM
fnp-3766	558	3	.	.	PUNCT
fnp-3766	559	1	2013;8(6):e67680	2013;8(6):e67680	X
fnp-3766	559	2	.	.	PUNCT
fnp-3766	560	1	44	44	NUM
fnp-3766	560	2	.	.	PUNCT
fnp-3766	561	1	vallet	vallet	PROPN
fnp-3766	561	2	pg	pg	PROPN
fnp-3766	561	3	,	,	PUNCT
fnp-3766	561	4	guntern	guntern	ADJ
fnp-3766	561	5	r	r	NOUN
fnp-3766	561	6	,	,	PUNCT
fnp-3766	561	7	hof	hof	NOUN
fnp-3766	561	8	pr	pr	NOUN
fnp-3766	561	9	,	,	PUNCT
fnp-3766	561	10	golaz	golaz	PROPN
fnp-3766	561	11	j	j	PROPN
fnp-3766	561	12	,	,	PUNCT
fnp-3766	561	13	delacourte	delacourte	PROPN
fnp-3766	561	14	a	a	PRON
fnp-3766	561	15	,	,	PUNCT
fnp-3766	561	16	robakis	robakis	PROPN
fnp-3766	561	17	nk	nk	PROPN
fnp-3766	561	18	,	,	PUNCT
fnp-3766	561	19	et	et	PROPN
fnp-3766	561	20	al	al	PROPN
fnp-3766	561	21	.	.	PUNCT
fnp-3766	562	1	a	a	DET
fnp-3766	562	2	comparative	comparative	ADJ
fnp-3766	562	3	study	study	NOUN
fnp-3766	562	4	of	of	ADP
fnp-3766	562	5	histological	histological	ADJ
fnp-3766	562	6	and	and	CCONJ
fnp-3766	562	7	immunohistochemical	immunohistochemical	ADJ
fnp-3766	562	8	methods	method	NOUN
fnp-3766	562	9	for	for	ADP
fnp-3766	562	10	neurofibrillary	neurofibrillary	ADJ
fnp-3766	562	11	tangles	tangle	NOUN
fnp-3766	562	12	and	and	CCONJ
fnp-3766	562	13	senile	senile	ADJ
fnp-3766	562	14	plaques	plaque	NOUN
fnp-3766	562	15	in	in	ADP
fnp-3766	562	16	alzheimer	alzheimer	PROPN
fnp-3766	562	17	's	's	PART
fnp-3766	562	18	disease	disease	NOUN
fnp-3766	562	19	.	.	PUNCT
fnp-3766	563	1	acta	acta	PROPN
fnp-3766	563	2	neuropathol	neuropathol	PROPN
fnp-3766	563	3	.	.	PUNCT
fnp-3766	564	1	1992;83(2):170	1992;83(2):170	NUM
fnp-3766	564	2	-	-	SYM
fnp-3766	564	3	8	8	NUM
fnp-3766	564	4	.	.	X
fnp-3766	564	5	45	45	NUM
fnp-3766	564	6	.	.	PUNCT
fnp-3766	564	7	hanna	hanna	PROPN
fnp-3766	565	1	a	a	PRON
fnp-3766	565	2	,	,	PUNCT
fnp-3766	565	3	iremonger	iremonger	PROPN
fnp-3766	565	4	k	k	PROPN
fnp-3766	565	5	,	,	PUNCT
fnp-3766	565	6	das	das	PROPN
fnp-3766	565	7	p	p	X
fnp-3766	565	8	,	,	PUNCT
fnp-3766	565	9	dickson	dickson	PROPN
fnp-3766	565	10	d	d	PROPN
fnp-3766	565	11	,	,	PUNCT
fnp-3766	565	12	golde	golde	PROPN
fnp-3766	565	13	t	t	PROPN
fnp-3766	565	14	,	,	PUNCT
fnp-3766	565	15	janus	janus	PROPN
fnp-3766	565	16	c.	c.	PROPN
fnp-3766	565	17	age	age	NOUN
fnp-3766	565	18	-	-	PUNCT
fnp-3766	565	19	related	relate	VERB
fnp-3766	565	20	increase	increase	NOUN
fnp-3766	565	21	in	in	ADP
fnp-3766	565	22	amyloid	amyloid	NOUN
fnp-3766	565	23	plaque	plaque	NOUN
fnp-3766	565	24	burden	burden	NOUN
fnp-3766	565	25	is	be	AUX
fnp-3766	565	26	associated	associate	VERB
fnp-3766	565	27	with	with	ADP
fnp-3766	565	28	impairment	impairment	NOUN
fnp-3766	565	29	in	in	ADP
fnp-3766	565	30	conditioned	condition	VERB
fnp-3766	565	31	fear	fear	NOUN
fnp-3766	565	32	memory	memory	NOUN
fnp-3766	565	33	in	in	ADP
fnp-3766	565	34	crnd8	crnd8	PROPN
fnp-3766	565	35	mouse	mouse	NOUN
fnp-3766	565	36	model	model	NOUN
fnp-3766	565	37	of	of	ADP
fnp-3766	565	38	amyloidosis	amyloidosis	NOUN
fnp-3766	565	39	.	.	PUNCT
fnp-3766	566	1	alzheimers	alzheimer	NOUN
fnp-3766	566	2	res	re	VERB
fnp-3766	566	3	ther	ther	ADV
fnp-3766	566	4	.	.	PUNCT
fnp-3766	567	1	2012;4(3):21	2012;4(3):21	X
fnp-3766	567	2	.	.	PROPN
fnp-3766	568	1	46	46	NUM
fnp-3766	568	2	.	.	PUNCT
fnp-3766	569	1	chakrabarty	chakrabarty	PROPN
fnp-3766	569	2	p	p	X
fnp-3766	569	3	,	,	PUNCT
fnp-3766	569	4	hudson	hudson	PROPN
fnp-3766	569	5	vj	vj	PROPN
fnp-3766	569	6	,	,	PUNCT
fnp-3766	569	7	iii	iii	PROPN
fnp-3766	569	8	,	,	PUNCT
fnp-3766	569	9	sacino	sacino	PROPN
fnp-3766	569	10	an	an	PROPN
fnp-3766	569	11	,	,	PUNCT
fnp-3766	569	12	brooks	brooks	PROPN
fnp-3766	569	13	mm	mm	PROPN
fnp-3766	569	14	,	,	PUNCT
fnp-3766	569	15	d'alton	d'alton	PROPN
fnp-3766	569	16	s	s	PROPN
fnp-3766	569	17	,	,	PUNCT
fnp-3766	569	18	lewis	lewis	PROPN
fnp-3766	569	19	j	j	PROPN
fnp-3766	569	20	,	,	PUNCT
fnp-3766	569	21	et	et	PROPN
fnp-3766	569	22	al	al	PROPN
fnp-3766	569	23	.	.	PROPN
fnp-3766	570	1	inefficient	inefficient	ADJ
fnp-3766	570	2	induction	induction	NOUN
fnp-3766	570	3	and	and	CCONJ
fnp-3766	570	4	spread	spread	VERB
fnp-3766	570	5	of	of	ADP
fnp-3766	570	6	seeded	seeded	ADJ
fnp-3766	570	7	tau	tau	PROPN
fnp-3766	570	8	pathology	pathology	NOUN
fnp-3766	570	9	in	in	ADP
fnp-3766	570	10	p301l	p301l	PROPN
fnp-3766	570	11	mouse	mouse	NOUN
fnp-3766	570	12	model	model	NOUN
fnp-3766	570	13	of	of	ADP
fnp-3766	570	14	tauopathy	tauopathy	NOUN
fnp-3766	570	15	suggests	suggest	VERB
fnp-3766	570	16	inherent	inherent	ADJ
fnp-3766	570	17	physiological	physiological	ADJ
fnp-3766	570	18	barriers	barrier	NOUN
fnp-3766	570	19	to	to	ADP
fnp-3766	570	20	transmission	transmission	NOUN
fnp-3766	570	21	.	.	PUNCT
fnp-3766	571	1	acta	acta	PROPN
fnp-3766	571	2	neuropathol	neuropathol	PROPN
fnp-3766	571	3	.	.	PUNCT
fnp-3766	572	1	2015;130(2):303	2015;130(2):303	NUM
fnp-3766	572	2	-	-	SYM
fnp-3766	572	3	5	5	NUM
fnp-3766	572	4	.	.	X
fnp-3766	573	1	47	47	NUM
fnp-3766	573	2	.	.	PUNCT
fnp-3766	574	1	lewis	lewis	PROPN
fnp-3766	574	2	j	j	PROPN
fnp-3766	574	3	,	,	PUNCT
fnp-3766	574	4	mcgowan	mcgowan	PROPN
fnp-3766	574	5	e	e	PROPN
fnp-3766	574	6	,	,	PUNCT
fnp-3766	574	7	rockwood	rockwood	PROPN
fnp-3766	574	8	j	j	PROPN
fnp-3766	574	9	,	,	PUNCT
fnp-3766	574	10	melrose	melrose	PROPN
fnp-3766	574	11	h	h	PROPN
fnp-3766	574	12	,	,	PUNCT
fnp-3766	574	13	nacharaju	nacharaju	ADV
fnp-3766	574	14	p	p	X
fnp-3766	574	15	,	,	PUNCT
fnp-3766	574	16	van	van	PROPN
fnp-3766	574	17	slegtenhorst	slegtenhorst	PROPN
fnp-3766	574	18	m	m	PROPN
fnp-3766	574	19	,	,	PUNCT
fnp-3766	574	20	et	et	PROPN
fnp-3766	574	21	al	al	PROPN
fnp-3766	574	22	.	.	PROPN
fnp-3766	574	23	neurofibrillary	neurofibrillary	ADJ
fnp-3766	574	24	tangles	tangle	NOUN
fnp-3766	574	25	,	,	PUNCT
fnp-3766	574	26	amyotrophy	amyotrophy	NOUN
fnp-3766	574	27	and	and	CCONJ
fnp-3766	574	28	progressive	progressive	ADJ
fnp-3766	574	29	motor	motor	NOUN
fnp-3766	574	30	disturbance	disturbance	NOUN
fnp-3766	574	31	in	in	ADP
fnp-3766	574	32	mice	mouse	NOUN
fnp-3766	574	33	expressing	express	VERB
fnp-3766	574	34	mutant	mutant	NOUN
fnp-3766	574	35	(	(	PUNCT
fnp-3766	574	36	p301l	p301l	PROPN
fnp-3766	574	37	)	)	PUNCT
fnp-3766	574	38	tau	tau	PROPN
fnp-3766	574	39	protein	protein	NOUN
fnp-3766	574	40	.	.	PUNCT
fnp-3766	575	1	nat	nat	PROPN
fnp-3766	575	2	genet	genet	PROPN
fnp-3766	575	3	.	.	PUNCT
fnp-3766	576	1	2000;25(4):402	2000;25(4):402	NUM
fnp-3766	576	2	-	-	SYM
fnp-3766	576	3	5	5	NUM
fnp-3766	576	4	.	.	NUM
fnp-3766	576	5	48	48	NUM
fnp-3766	576	6	.	.	PUNCT
fnp-3766	577	1	xu	xu	PROPN
fnp-3766	577	2	g	g	PROPN
fnp-3766	577	3	,	,	PUNCT
fnp-3766	577	4	fromholt	fromholt	NOUN
fnp-3766	577	5	se	se	PROPN
fnp-3766	577	6	,	,	PUNCT
fnp-3766	577	7	chakrabarty	chakrabarty	PROPN
fnp-3766	577	8	p	p	X
fnp-3766	577	9	,	,	PUNCT
fnp-3766	577	10	zhu	zhu	PROPN
fnp-3766	577	11	f	f	X
fnp-3766	577	12	,	,	PUNCT
fnp-3766	577	13	liu	liu	PROPN
fnp-3766	577	14	x	x	PROPN
fnp-3766	577	15	,	,	PUNCT
fnp-3766	577	16	pace	pace	NOUN
fnp-3766	577	17	mc	mc	PROPN
fnp-3766	577	18	,	,	PUNCT
fnp-3766	577	19	et	et	PROPN
fnp-3766	577	20	al	al	PROPN
fnp-3766	577	21	.	.	PUNCT
fnp-3766	577	22	diversity	diversity	NOUN
fnp-3766	577	23	in	in	ADP
fnp-3766	577	24	abeta	abeta	PROPN
fnp-3766	577	25	deposit	deposit	NOUN
fnp-3766	577	26	morphology	morphology	NOUN
fnp-3766	577	27	and	and	CCONJ
fnp-3766	577	28	secondary	secondary	ADJ
fnp-3766	577	29	proteome	proteome	PROPN
fnp-3766	577	30	insolubility	insolubility	NOUN
fnp-3766	577	31	across	across	ADP
fnp-3766	577	32	models	model	NOUN
fnp-3766	577	33	of	of	ADP
fnp-3766	577	34	alzheimer	alzheimer	NOUN
fnp-3766	577	35	-	-	PUNCT
fnp-3766	577	36	type	type	NOUN
fnp-3766	577	37	amyloidosis	amyloidosis	NOUN
fnp-3766	577	38	.	.	PUNCT
fnp-3766	578	1	acta	acta	PROPN
fnp-3766	578	2	neuropathol	neuropathol	PROPN
fnp-3766	578	3	commun	commun	PROPN
fnp-3766	578	4	.	.	PUNCT
fnp-3766	579	1	2020;8(1):43	2020;8(1):43	NUM
fnp-3766	579	2	.	.	NOUN
fnp-3766	580	1	49	49	NUM
fnp-3766	580	2	.	.	PUNCT
fnp-3766	581	1	walker	walker	PROPN
fnp-3766	581	2	lc	lc	PROPN
fnp-3766	581	3	,	,	PUNCT
fnp-3766	581	4	callahan	callahan	PROPN
fnp-3766	581	5	mj	mj	PROPN
fnp-3766	581	6	,	,	PUNCT
fnp-3766	581	7	bian	bian	PROPN
fnp-3766	581	8	f	f	PROPN
fnp-3766	581	9	,	,	PUNCT
fnp-3766	581	10	durham	durham	PROPN
fnp-3766	581	11	ra	ra	PROPN
fnp-3766	581	12	,	,	PUNCT
fnp-3766	581	13	roher	roher	ADV
fnp-3766	581	14	ae	ae	PROPN
fnp-3766	581	15	,	,	PUNCT
fnp-3766	581	16	lipinski	lipinski	PROPN
fnp-3766	581	17	wj	wj	PROPN
fnp-3766	581	18	.	.	PUNCT
fnp-3766	582	1	exogenous	exogenous	ADJ
fnp-3766	582	2	induction	induction	NOUN
fnp-3766	582	3	of	of	ADP
fnp-3766	582	4	cerebral	cerebral	ADJ
fnp-3766	582	5	beta	beta	NOUN
fnp-3766	582	6	-	-	PUNCT
fnp-3766	582	7	amyloidosis	amyloidosis	NOUN
fnp-3766	582	8	in	in	ADP
fnp-3766	582	9	betaapp	betaapp	ADJ
fnp-3766	582	10	-	-	PUNCT
fnp-3766	582	11	transgenic	transgenic	NOUN
fnp-3766	582	12	mice	mouse	NOUN
fnp-3766	582	13	.	.	PUNCT
fnp-3766	583	1	peptides	peptide	NOUN
fnp-3766	583	2	.	.	PUNCT
fnp-3766	584	1	2002;23(7):1241	2002;23(7):1241	NUM
fnp-3766	584	2	-	-	SYM
fnp-3766	584	3	7	7	NUM
fnp-3766	584	4	.	.	NOUN
fnp-3766	584	5	50	50	NUM
fnp-3766	584	6	.	.	PUNCT
fnp-3766	584	7	mckinley	mckinley	PROPN
fnp-3766	584	8	mp	mp	PROPN
fnp-3766	584	9	,	,	PUNCT
fnp-3766	584	10	dearmond	dearmond	PROPN
fnp-3766	584	11	sj	sj	PROPN
fnp-3766	584	12	,	,	PUNCT
fnp-3766	584	13	torchia	torchia	VERB
fnp-3766	584	14	m	m	PROPN
fnp-3766	584	15	,	,	PUNCT
fnp-3766	584	16	mobley	mobley	PROPN
fnp-3766	584	17	wc	wc	PROPN
fnp-3766	584	18	,	,	PUNCT
fnp-3766	584	19	prusiner	prusiner	NOUN
fnp-3766	584	20	sb	sb	PROPN
fnp-3766	584	21	.	.	PROPN
fnp-3766	584	22	acceleration	acceleration	NOUN
fnp-3766	584	23	of	of	ADP
fnp-3766	584	24	scrapie	scrapie	NOUN
fnp-3766	584	25	in	in	ADP
fnp-3766	584	26	neonatal	neonatal	ADJ
fnp-3766	584	27	syrian	syrian	ADJ
fnp-3766	584	28	hamsters	hamster	NOUN
fnp-3766	584	29	.	.	PUNCT
fnp-3766	585	1	neurology	neurology	NOUN
fnp-3766	585	2	.	.	PUNCT
fnp-3766	586	1	1989;39(10):1319	1989;39(10):1319	NUM
fnp-3766	586	2	-	-	SYM
fnp-3766	586	3	24	24	NUM
fnp-3766	586	4	.	.	PUNCT
fnp-3766	587	1	51	51	NUM
fnp-3766	587	2	.	.	PUNCT
fnp-3766	588	1	ayers	ayers	PROPN
fnp-3766	588	2	ji	ji	PROPN
fnp-3766	588	3	,	,	PUNCT
fnp-3766	588	4	fromholt	fromholt	PROPN
fnp-3766	588	5	s	s	PART
fnp-3766	588	6	,	,	PUNCT
fnp-3766	588	7	koch	koch	PROPN
fnp-3766	588	8	m	m	PROPN
fnp-3766	588	9	,	,	PUNCT
fnp-3766	588	10	debosier	debosier	PROPN
fnp-3766	588	11	a	a	PROPN
fnp-3766	588	12	,	,	PUNCT
fnp-3766	588	13	mcmahon	mcmahon	PROPN
fnp-3766	588	14	b	b	PROPN
fnp-3766	588	15	,	,	PUNCT
fnp-3766	588	16	xu	xu	PROPN
fnp-3766	588	17	g	g	PROPN
fnp-3766	588	18	,	,	PUNCT
fnp-3766	588	19	et	et	PROPN
fnp-3766	588	20	al	al	PROPN
fnp-3766	588	21	.	.	PUNCT
fnp-3766	588	22	experimental	experimental	ADJ
fnp-3766	588	23	transmissibility	transmissibility	NOUN
fnp-3766	588	24	of	of	ADP
fnp-3766	588	25	mutant	mutant	ADJ
fnp-3766	588	26	sod1	sod1	ADJ
fnp-3766	588	27	motor	motor	PROPN
fnp-3766	588	28	neuron	neuron	PROPN
fnp-3766	588	29	disease	disease	PROPN
fnp-3766	588	30	.	.	PUNCT
fnp-3766	589	1	acta	acta	PROPN
fnp-3766	589	2	neuropathol	neuropathol	PROPN
fnp-3766	589	3	.	.	PUNCT
fnp-3766	590	1	2014;128(6):791	2014;128(6):791	X
fnp-3766	590	2	-	-	SYM
fnp-3766	590	3	803	803	NUM
fnp-3766	590	4	.	.	PUNCT
fnp-3766	591	1	52	52	NUM
fnp-3766	591	2	.	.	PUNCT
fnp-3766	592	1	bidhendi	bidhendi	PROPN
fnp-3766	592	2	ee	ee	PROPN
fnp-3766	592	3	,	,	PUNCT
fnp-3766	592	4	bergh	bergh	PROPN
fnp-3766	592	5	j	j	PROPN
fnp-3766	592	6	,	,	PUNCT
fnp-3766	592	7	zetterstrom	zetterstrom	ADP
fnp-3766	592	8	p	p	PROPN
fnp-3766	592	9	,	,	PUNCT
fnp-3766	592	10	andersen	andersen	PROPN
fnp-3766	592	11	pm	pm	PROPN
fnp-3766	592	12	,	,	PUNCT
fnp-3766	592	13	marklund	marklund	NOUN
fnp-3766	592	14	sl	sl	NOUN
fnp-3766	592	15	,	,	PUNCT
fnp-3766	592	16	brannstrom	brannstrom	NOUN
fnp-3766	592	17	t.	t.	PROPN
fnp-3766	592	18	two	two	NUM
fnp-3766	592	19	superoxide	superoxide	NOUN
fnp-3766	592	20	dismutase	dismutase	NOUN
fnp-3766	592	21	prion	prion	NOUN
fnp-3766	592	22	strains	strain	NOUN
fnp-3766	592	23	transmit	transmit	VERB
fnp-3766	592	24	amyotrophic	amyotrophic	ADJ
fnp-3766	592	25	lateral	lateral	ADJ
fnp-3766	592	26	sclerosis	sclerosis	NOUN
fnp-3766	592	27	-	-	PUNCT
fnp-3766	592	28	like	like	ADJ
fnp-3766	592	29	disease	disease	NOUN
fnp-3766	592	30	.	.	PUNCT
fnp-3766	593	1	j	j	PROPN
fnp-3766	593	2	clin	clin	PROPN
fnp-3766	593	3	invest	invest	VERB
fnp-3766	593	4	.	.	PUNCT
fnp-3766	594	1	2016;126(6):2249	2016;126(6):2249	NUM
fnp-3766	594	2	-	-	SYM
fnp-3766	594	3	53	53	NUM
fnp-3766	594	4	.	.	PUNCT
fnp-3766	595	1	53	53	NUM
fnp-3766	595	2	.	.	PUNCT
fnp-3766	596	1	eisele	eisele	PROPN
fnp-3766	596	2	ys	ys	PROPN
fnp-3766	596	3	,	,	PUNCT
fnp-3766	596	4	bolmont	bolmont	VERB
fnp-3766	596	5	t	t	PROPN
fnp-3766	596	6	,	,	PUNCT
fnp-3766	596	7	heikenwalder	heikenwalder	ADJ
fnp-3766	596	8	m	m	PROPN
fnp-3766	596	9	,	,	PUNCT
fnp-3766	596	10	langer	langer	PROPN
fnp-3766	596	11	f	f	PROPN
fnp-3766	596	12	,	,	PUNCT
fnp-3766	596	13	jacobson	jacobson	PROPN
fnp-3766	596	14	lh	lh	PROPN
fnp-3766	596	15	,	,	PUNCT
fnp-3766	596	16	yan	yan	PROPN
fnp-3766	597	1	zx	zx	PROPN
fnp-3766	597	2	,	,	PUNCT
fnp-3766	598	1	et	et	PROPN
fnp-3766	598	2	al	al	PROPN
fnp-3766	598	3	.	.	PROPN
fnp-3766	598	4	induction	induction	NOUN
fnp-3766	598	5	of	of	ADP
fnp-3766	598	6	cerebral	cerebral	ADJ
fnp-3766	598	7	beta	beta	NOUN
fnp-3766	598	8	-	-	PUNCT
fnp-3766	598	9	amyloidosis	amyloidosis	NOUN
fnp-3766	598	10	:	:	PUNCT
fnp-3766	598	11	intracerebral	intracerebral	ADJ
fnp-3766	598	12	versus	versus	ADP
fnp-3766	598	13	systemic	systemic	ADJ
fnp-3766	598	14	abeta	abeta	PROPN
fnp-3766	598	15	inoculation	inoculation	PROPN
fnp-3766	598	16	.	.	PUNCT
fnp-3766	599	1	proc	proc	PROPN
fnp-3766	599	2	natl	natl	PROPN
fnp-3766	599	3	acad	acad	PROPN
fnp-3766	599	4	sci	sci	PROPN
fnp-3766	599	5	u	u	PROPN
fnp-3766	599	6	s	s	NOUN
fnp-3766	599	7	a.	a.	NOUN
fnp-3766	599	8	2009;106(31):12926	2009;106(31):12926	NUM
fnp-3766	599	9	-	-	SYM
fnp-3766	599	10	31	31	NUM
fnp-3766	599	11	.	.	PUNCT
fnp-3766	600	1	54	54	NUM
fnp-3766	600	2	.	.	PUNCT
fnp-3766	601	1	ziegler	ziegler	NOUN
fnp-3766	601	2	-	-	PUNCT
fnp-3766	601	3	waldkirch	waldkirch	PROPN
fnp-3766	601	4	s	s	PROPN
fnp-3766	601	5	,	,	PUNCT
fnp-3766	601	6	d'errico	d'errico	PROPN
fnp-3766	601	7	p	p	PROPN
fnp-3766	601	8	,	,	PUNCT
fnp-3766	601	9	sauer	sauer	PROPN
fnp-3766	601	10	jf	jf	PROPN
fnp-3766	601	11	,	,	PUNCT
fnp-3766	601	12	erny	erny	VERB
fnp-3766	601	13	d	d	PROPN
fnp-3766	601	14	,	,	PUNCT
fnp-3766	601	15	savanthrapadian	savanthrapadian	PROPN
fnp-3766	601	16	s	s	NOUN
fnp-3766	601	17	,	,	PUNCT
fnp-3766	601	18	loreth	loreth	PROPN
fnp-3766	601	19	d	d	PROPN
fnp-3766	601	20	,	,	PUNCT
fnp-3766	601	21	et	et	PROPN
fnp-3766	601	22	al	al	PROPN
fnp-3766	601	23	.	.	PROPN
fnp-3766	601	24	seed	seed	NOUN
fnp-3766	601	25	-	-	PUNCT
fnp-3766	601	26	induced	induce	VERB
fnp-3766	601	27	abeta	abeta	NOUN
fnp-3766	601	28	deposition	deposition	NOUN
fnp-3766	601	29	is	be	AUX
fnp-3766	601	30	modulated	modulate	VERB
fnp-3766	601	31	by	by	ADP
fnp-3766	601	32	microglia	microglia	NOUN
fnp-3766	601	33	under	under	ADP
fnp-3766	601	34	environmental	environmental	ADJ
fnp-3766	601	35	enrichment	enrichment	NOUN
fnp-3766	601	36	in	in	ADP
fnp-3766	601	37	a	a	DET
fnp-3766	601	38	mouse	mouse	NOUN
fnp-3766	601	39	model	model	NOUN
fnp-3766	601	40	of	of	ADP
fnp-3766	601	41	alzheimer	alzheimer	PROPN
fnp-3766	601	42	's	's	PART
fnp-3766	601	43	disease	disease	NOUN
fnp-3766	601	44	.	.	PUNCT
fnp-3766	602	1	embo	embo	PROPN
fnp-3766	602	2	j.	j.	PROPN
fnp-3766	602	3	2018;37(2):167	2018;37(2):167	PROPN
fnp-3766	602	4	-	-	PUNCT
fnp-3766	602	5	82	82	NUM
fnp-3766	602	6	.	.	PUNCT
fnp-3766	603	1	55	55	NUM
fnp-3766	603	2	.	.	PUNCT
fnp-3766	604	1	langer	langer	PROPN
fnp-3766	604	2	f	f	PROPN
fnp-3766	604	3	,	,	PUNCT
fnp-3766	604	4	eisele	eisele	PROPN
fnp-3766	604	5	ys	ys	VERB
fnp-3766	604	6	,	,	PUNCT
fnp-3766	604	7	fritschi	fritschi	VERB
fnp-3766	604	8	sk	sk	NOUN
fnp-3766	604	9	,	,	PUNCT
fnp-3766	604	10	staufenbiel	staufenbiel	PROPN
fnp-3766	604	11	m	m	PROPN
fnp-3766	604	12	,	,	PUNCT
fnp-3766	604	13	walker	walker	PROPN
fnp-3766	604	14	lc	lc	PROPN
fnp-3766	604	15	,	,	PUNCT
fnp-3766	604	16	jucker	jucker	PROPN
fnp-3766	604	17	m.	m.	NOUN
fnp-3766	604	18	soluble	soluble	PROPN
fnp-3766	604	19	abeta	abeta	PROPN
fnp-3766	604	20	seeds	seed	NOUN
fnp-3766	604	21	are	be	AUX
fnp-3766	604	22	potent	potent	ADJ
fnp-3766	604	23	inducers	inducer	NOUN
fnp-3766	604	24	of	of	ADP
fnp-3766	604	25	cerebral	cerebral	ADJ
fnp-3766	604	26	beta	beta	NOUN
fnp-3766	604	27	-	-	PUNCT
fnp-3766	604	28	amyloid	amyloid	NOUN
fnp-3766	604	29	deposition	deposition	NOUN
fnp-3766	604	30	.	.	PUNCT
fnp-3766	605	1	j	j	PROPN
fnp-3766	605	2	neurosci	neurosci	PROPN
fnp-3766	605	3	.	.	PUNCT
fnp-3766	606	1	2011;31(41):14488	2011;31(41):14488	NUM
fnp-3766	606	2	-	-	SYM
fnp-3766	606	3	95	95	NUM
fnp-3766	606	4	.	.	PUNCT
fnp-3766	607	1	56	56	NUM
fnp-3766	607	2	.	.	PUNCT
fnp-3766	608	1	peeraer	peeraer	PROPN
fnp-3766	608	2	e	e	PROPN
fnp-3766	608	3	,	,	PUNCT
fnp-3766	608	4	bottelbergs	bottelbergs	X
fnp-3766	608	5	a	a	PRON
fnp-3766	608	6	,	,	PUNCT
fnp-3766	608	7	van	van	PROPN
fnp-3766	608	8	kolen	kolen	PROPN
fnp-3766	608	9	k	k	PROPN
fnp-3766	608	10	,	,	PUNCT
fnp-3766	608	11	stancu	stancu	PROPN
fnp-3766	608	12	ic	ic	PROPN
fnp-3766	608	13	,	,	PUNCT
fnp-3766	608	14	vasconcelos	vasconcelos	PROPN
fnp-3766	608	15	b	b	PROPN
fnp-3766	608	16	,	,	PUNCT
fnp-3766	608	17	mahieu	mahieu	PROPN
fnp-3766	608	18	m	m	PROPN
fnp-3766	608	19	,	,	PUNCT
fnp-3766	608	20	et	et	PROPN
fnp-3766	608	21	al	al	PROPN
fnp-3766	608	22	.	.	PUNCT
fnp-3766	609	1	intracerebral	intracerebral	ADJ
fnp-3766	609	2	injection	injection	NOUN
fnp-3766	609	3	of	of	ADP
fnp-3766	609	4	preformed	preformed	ADJ
fnp-3766	609	5	synthetic	synthetic	NOUN
fnp-3766	609	6	tau	tau	PROPN
fnp-3766	609	7	fibrils	fibril	NOUN
fnp-3766	609	8	initiates	initiate	VERB
fnp-3766	609	9	widespread	widespread	ADJ
fnp-3766	609	10	tauopathy	tauopathy	NOUN
fnp-3766	609	11	and	and	CCONJ
fnp-3766	609	12	neuronal	neuronal	ADJ
fnp-3766	609	13	loss	loss	NOUN
fnp-3766	609	14	in	in	ADP
fnp-3766	609	15	the	the	DET
fnp-3766	609	16	brains	brain	NOUN
fnp-3766	609	17	of	of	ADP
fnp-3766	609	18	tau	tau	PROPN
fnp-3766	609	19	transgenic	transgenic	NOUN
fnp-3766	609	20	mice	mouse	NOUN
fnp-3766	609	21	.	.	PUNCT
fnp-3766	610	1	neurobiol	neurobiol	PROPN
fnp-3766	610	2	dis	dis	PROPN
fnp-3766	610	3	.	.	PUNCT
fnp-3766	611	1	2015;73:83	2015;73:83	NUM
fnp-3766	611	2	-	-	SYM
fnp-3766	611	3	95	95	NUM
fnp-3766	611	4	.	.	PUNCT
fnp-3766	612	1	57	57	NUM
fnp-3766	612	2	.	.	PUNCT
fnp-3766	612	3	clavaguera	clavaguera	NOUN
fnp-3766	612	4	f	f	PROPN
fnp-3766	612	5	,	,	PUNCT
fnp-3766	612	6	bolmont	bolmont	PROPN
fnp-3766	612	7	t	t	PROPN
fnp-3766	612	8	,	,	PUNCT
fnp-3766	612	9	crowther	crowther	PROPN
fnp-3766	612	10	ra	ra	PROPN
fnp-3766	612	11	,	,	PUNCT
fnp-3766	612	12	abramowski	abramowski	NOUN
fnp-3766	612	13	d	d	PROPN
fnp-3766	612	14	,	,	PUNCT
fnp-3766	612	15	frank	frank	PROPN
fnp-3766	612	16	s	s	PROPN
fnp-3766	612	17	,	,	PUNCT
fnp-3766	612	18	probst	probst	NOUN
fnp-3766	612	19	a	a	X
fnp-3766	612	20	,	,	PUNCT
fnp-3766	612	21	et	et	PROPN
fnp-3766	612	22	al	al	PROPN
fnp-3766	612	23	.	.	PUNCT
fnp-3766	612	24	transmission	transmission	NOUN
fnp-3766	612	25	and	and	CCONJ
fnp-3766	612	26	spreading	spread	VERB
fnp-3766	612	27	of	of	ADP
fnp-3766	612	28	tauopathy	tauopathy	NOUN
fnp-3766	612	29	in	in	ADP
fnp-3766	612	30	transgenic	transgenic	NOUN
fnp-3766	612	31	mouse	mouse	NOUN
fnp-3766	612	32	brain	brain	NOUN
fnp-3766	612	33	.	.	PUNCT
fnp-3766	613	1	nat	nat	NOUN
fnp-3766	613	2	cell	cell	NOUN
fnp-3766	613	3	biol	biol	PROPN
fnp-3766	613	4	.	.	PUNCT
fnp-3766	614	1	2009;11(7):909	2009;11(7):909	NUM
fnp-3766	614	2	-	-	SYM
fnp-3766	614	3	13	13	NUM
fnp-3766	614	4	.	.	PUNCT
fnp-3766	615	1	58	58	NUM
fnp-3766	615	2	.	.	PUNCT
fnp-3766	616	1	guo	guo	PROPN
fnp-3766	616	2	jl	jl	PROPN
fnp-3766	616	3	,	,	PUNCT
fnp-3766	616	4	narasimhan	narasimhan	PROPN
fnp-3766	616	5	s	s	PROPN
fnp-3766	616	6	,	,	PUNCT
fnp-3766	616	7	changolkar	changolkar	NOUN
fnp-3766	616	8	l	l	NOUN
fnp-3766	616	9	,	,	PUNCT
fnp-3766	616	10	he	he	PRON
fnp-3766	616	11	z	z	AUX
fnp-3766	616	12	,	,	PUNCT
fnp-3766	616	13	stieber	stieber	VERB
fnp-3766	616	14	a	a	PRON
fnp-3766	616	15	,	,	PUNCT
fnp-3766	616	16	zhang	zhang	PROPN
fnp-3766	616	17	b	b	PROPN
fnp-3766	616	18	,	,	PUNCT
fnp-3766	616	19	et	et	PROPN
fnp-3766	616	20	al	al	PROPN
fnp-3766	616	21	.	.	PROPN
fnp-3766	617	1	unique	unique	ADJ
fnp-3766	617	2	pathological	pathological	ADJ
fnp-3766	617	3	tau	tau	NOUN
fnp-3766	617	4	conformers	conformer	NOUN
fnp-3766	617	5	from	from	ADP
fnp-3766	617	6	alzheimer	alzheimer	PROPN
fnp-3766	617	7	's	's	PART
fnp-3766	617	8	brains	brain	NOUN
fnp-3766	617	9	transmit	transmit	VERB
fnp-3766	617	10	tau	tau	PROPN
fnp-3766	617	11	pathology	pathology	NOUN
fnp-3766	617	12	in	in	ADP
fnp-3766	617	13	nontransgenic	nontransgenic	ADJ
fnp-3766	617	14	mice	mouse	NOUN
fnp-3766	617	15	.	.	PUNCT
fnp-3766	618	1	j	j	PROPN
fnp-3766	618	2	exp	exp	NOUN
fnp-3766	618	3	med	med	PROPN
fnp-3766	618	4	.	.	PUNCT
fnp-3766	619	1	2016;213(12):2635	2016;213(12):2635	X
fnp-3766	619	2	-	-	SYM
fnp-3766	619	3	54	54	NUM
fnp-3766	619	4	.	.	PUNCT
fnp-3766	620	1	59	59	NUM
fnp-3766	620	2	.	.	PUNCT
fnp-3766	620	3	guo	guo	PROPN
fnp-3766	620	4	jl	jl	PROPN
fnp-3766	620	5	,	,	PUNCT
fnp-3766	620	6	lee	lee	PROPN
fnp-3766	620	7	vm	vm	PROPN
fnp-3766	620	8	.	.	PROPN
fnp-3766	620	9	neurofibrillary	neurofibrillary	ADJ
fnp-3766	620	10	tangle	tangle	NOUN
fnp-3766	620	11	-	-	PUNCT
fnp-3766	620	12	like	like	VERB
fnp-3766	620	13	tau	tau	PROPN
fnp-3766	620	14	pathology	pathology	NOUN
fnp-3766	620	15	induced	induce	VERB
fnp-3766	620	16	by	by	ADP
fnp-3766	620	17	synthetic	synthetic	ADJ
fnp-3766	620	18	tau	tau	PROPN
fnp-3766	620	19	fibrils	fibril	NOUN
fnp-3766	620	20	in	in	ADP
fnp-3766	620	21	primary	primary	ADJ
fnp-3766	620	22	neurons	neuron	NOUN
fnp-3766	620	23	over	over	ADP
fnp-3766	620	24	-	-	PUNCT
fnp-3766	620	25	expressing	express	VERB
fnp-3766	620	26	mutant	mutant	NOUN
fnp-3766	620	27	tau	tau	PROPN
fnp-3766	620	28	.	.	PUNCT
fnp-3766	621	1	febs	febs	PROPN
fnp-3766	621	2	lett	lett	PROPN
fnp-3766	621	3	.	.	PUNCT
fnp-3766	622	1	2013;587(6):717	2013;587(6):717	NUM
fnp-3766	622	2	-	-	PUNCT
fnp-3766	622	3	23	23	NUM
fnp-3766	622	4	.	.	PUNCT
fnp-3766	623	1	60	60	NUM
fnp-3766	623	2	.	.	PUNCT
fnp-3766	624	1	boluda	boluda	PROPN
fnp-3766	624	2	s	s	PROPN
fnp-3766	624	3	,	,	PUNCT
fnp-3766	624	4	iba	iba	PROPN
fnp-3766	624	5	m	m	PROPN
fnp-3766	624	6	,	,	PUNCT
fnp-3766	624	7	zhang	zhang	PROPN
fnp-3766	624	8	b	b	PROPN
fnp-3766	624	9	,	,	PUNCT
fnp-3766	624	10	raible	raible	ADJ
fnp-3766	624	11	km	km	NOUN
fnp-3766	624	12	,	,	PUNCT
fnp-3766	624	13	lee	lee	PROPN
fnp-3766	624	14	vm	vm	PROPN
fnp-3766	624	15	,	,	PUNCT
fnp-3766	624	16	trojanowski	trojanowski	PROPN
fnp-3766	624	17	jq	jq	PROPN
fnp-3766	624	18	.	.	PUNCT
fnp-3766	625	1	differential	differential	ADJ
fnp-3766	625	2	induction	induction	NOUN
fnp-3766	625	3	and	and	CCONJ
fnp-3766	625	4	spread	spread	NOUN
fnp-3766	625	5	of	of	ADP
fnp-3766	625	6	tau	tau	PROPN
fnp-3766	625	7	pathology	pathology	NOUN
fnp-3766	625	8	in	in	ADP
fnp-3766	625	9	young	young	ADJ
fnp-3766	625	10	ps19	ps19	PROPN
fnp-3766	625	11	tau	tau	PROPN
fnp-3766	625	12	transgenic	transgenic	NOUN
fnp-3766	625	13	mice	mouse	NOUN
fnp-3766	625	14	following	follow	VERB
fnp-3766	625	15	intracerebral	intracerebral	ADJ
fnp-3766	625	16	injections	injection	NOUN
fnp-3766	625	17	of	of	ADP
fnp-3766	625	18	pathological	pathological	ADJ
fnp-3766	625	19	tau	tau	PROPN
fnp-3766	625	20	from	from	ADP
fnp-3766	625	21	alzheimer	alzheimer	PROPN
fnp-3766	625	22	's	's	PART
fnp-3766	625	23	disease	disease	NOUN
fnp-3766	625	24	or	or	CCONJ
fnp-3766	625	25	corticobasal	corticobasal	NOUN
fnp-3766	625	26	degeneration	degeneration	NOUN
fnp-3766	625	27	brains	brain	NOUN
fnp-3766	625	28	.	.	PUNCT
fnp-3766	626	1	acta	acta	PROPN
fnp-3766	626	2	neuropathol	neuropathol	PROPN
fnp-3766	626	3	.	.	PUNCT
fnp-3766	627	1	2015;129(2):221	2015;129(2):221	NUM
fnp-3766	627	2	-	-	SYM
fnp-3766	627	3	37	37	NUM
fnp-3766	627	4	.	.	NOUN
fnp-3766	627	5	61	61	NUM
fnp-3766	627	6	.	.	PUNCT
fnp-3766	628	1	narasimhan	narasimhan	PROPN
fnp-3766	628	2	s	s	PROPN
fnp-3766	628	3	,	,	PUNCT
fnp-3766	628	4	guo	guo	PROPN
fnp-3766	628	5	jl	jl	PROPN
fnp-3766	628	6	,	,	PUNCT
fnp-3766	628	7	changolkar	changolkar	PROPN
fnp-3766	628	8	l	l	NOUN
fnp-3766	628	9	,	,	PUNCT
fnp-3766	628	10	stieber	stieber	VERB
fnp-3766	628	11	a	a	PRON
fnp-3766	628	12	,	,	PUNCT
fnp-3766	628	13	mcbride	mcbride	PROPN
fnp-3766	628	14	jd	jd	PROPN
fnp-3766	628	15	,	,	PUNCT
fnp-3766	628	16	silva	silva	PROPN
fnp-3766	628	17	lv	lv	PROPN
fnp-3766	628	18	,	,	PUNCT
fnp-3766	628	19	et	et	PROPN
fnp-3766	628	20	al	al	PROPN
fnp-3766	628	21	.	.	PROPN
fnp-3766	629	1	pathological	pathological	PROPN
fnp-3766	629	2	tau	tau	PROPN
fnp-3766	629	3	strains	strain	VERB
fnp-3766	629	4	from	from	ADP
fnp-3766	629	5	human	human	ADJ
fnp-3766	629	6	brains	brain	NOUN
fnp-3766	629	7	recapitulate	recapitulate	VERB
fnp-3766	629	8	the	the	DET
fnp-3766	629	9	diversity	diversity	NOUN
fnp-3766	629	10	of	of	ADP
fnp-3766	629	11	tauopathies	tauopathie	NOUN
fnp-3766	629	12	in	in	ADP
fnp-3766	629	13	nontransgenic	nontransgenic	ADJ
fnp-3766	629	14	mouse	mouse	NOUN
fnp-3766	629	15	brain	brain	NOUN
fnp-3766	629	16	.	.	PUNCT
fnp-3766	630	1	j	j	PROPN
fnp-3766	630	2	neurosci	neurosci	PROPN
fnp-3766	630	3	.	.	PUNCT
fnp-3766	631	1	2017;37(47):11406	2017;37(47):11406	NUM
fnp-3766	631	2	-	-	SYM
fnp-3766	631	3	23	23	NUM
fnp-3766	631	4	.	.	PUNCT
fnp-3766	632	1	62	62	NUM
fnp-3766	632	2	.	.	PUNCT
fnp-3766	633	1	clavaguera	clavaguera	NOUN
fnp-3766	633	2	f	f	PROPN
fnp-3766	633	3	,	,	PUNCT
fnp-3766	633	4	akatsu	akatsu	ADJ
fnp-3766	633	5	h	h	NOUN
fnp-3766	633	6	,	,	PUNCT
fnp-3766	633	7	fraser	fraser	PROPN
fnp-3766	633	8	g	g	PROPN
fnp-3766	633	9	,	,	PUNCT
fnp-3766	633	10	crowther	crowther	PROPN
fnp-3766	633	11	ra	ra	PROPN
fnp-3766	633	12	,	,	PUNCT
fnp-3766	633	13	frank	frank	PROPN
fnp-3766	633	14	s	s	PROPN
fnp-3766	633	15	,	,	PUNCT
fnp-3766	633	16	hench	hench	PROPN
fnp-3766	633	17	j	j	PROPN
fnp-3766	633	18	,	,	PUNCT
fnp-3766	633	19	et	et	PROPN
fnp-3766	633	20	al	al	PROPN
fnp-3766	633	21	.	.	PUNCT
fnp-3766	634	1	brain	brain	NOUN
fnp-3766	634	2	homogenates	homogenate	NOUN
fnp-3766	634	3	from	from	ADP
fnp-3766	634	4	human	human	ADJ
fnp-3766	634	5	tauopathies	tauopathie	NOUN
fnp-3766	634	6	induce	induce	VERB
fnp-3766	634	7	tau	tau	PROPN
fnp-3766	634	8	inclusions	inclusion	NOUN
fnp-3766	634	9	in	in	ADP
fnp-3766	634	10	mouse	mouse	NOUN
fnp-3766	634	11	brain	brain	NOUN
fnp-3766	634	12	.	.	PUNCT
fnp-3766	635	1	proc	proc	PROPN
fnp-3766	635	2	natl	natl	PROPN
fnp-3766	635	3	acad	acad	PROPN
fnp-3766	635	4	sci	sci	PROPN
fnp-3766	635	5	u	u	PROPN
fnp-3766	635	6	s	s	NOUN
fnp-3766	635	7	a.	a.	NOUN
fnp-3766	635	8	2013;110(23):9535	2013;110(23):9535	NUM
fnp-3766	635	9	-	-	SYM
fnp-3766	635	10	40	40	NUM
fnp-3766	635	11	.	.	PUNCT
fnp-3766	636	1	63	63	NUM
fnp-3766	636	2	.	.	PUNCT
fnp-3766	637	1	masuda	masuda	PROPN
fnp-3766	637	2	-	-	PUNCT
fnp-3766	637	3	suzukake	suzukake	PROPN
fnp-3766	637	4	m	m	PROPN
fnp-3766	637	5	,	,	PUNCT
fnp-3766	637	6	nonaka	nonaka	PROPN
fnp-3766	637	7	t	t	PROPN
fnp-3766	637	8	,	,	PUNCT
fnp-3766	637	9	hosokawa	hosokawa	PROPN
fnp-3766	637	10	m	m	PRON
fnp-3766	637	11	,	,	PUNCT
fnp-3766	637	12	oikawa	oikawa	PROPN
fnp-3766	637	13	t	t	PROPN
fnp-3766	637	14	,	,	PUNCT
fnp-3766	637	15	arai	arai	PROPN
fnp-3766	637	16	t	t	PROPN
fnp-3766	637	17	,	,	PUNCT
fnp-3766	637	18	akiyama	akiyama	PROPN
fnp-3766	637	19	h	h	PROPN
fnp-3766	637	20	,	,	PUNCT
fnp-3766	637	21	et	et	PROPN
fnp-3766	637	22	al	al	PROPN
fnp-3766	637	23	.	.	PUNCT
fnp-3766	638	1	prion	prion	NOUN
fnp-3766	638	2	-	-	PUNCT
fnp-3766	638	3	like	like	ADJ
fnp-3766	638	4	spreading	spread	VERB
fnp-3766	638	5	of	of	ADP
fnp-3766	638	6	pathological	pathological	ADJ
fnp-3766	638	7	alpha	alpha	NOUN
fnp-3766	638	8	-	-	PUNCT
fnp-3766	638	9	synuclein	synuclein	NOUN
fnp-3766	638	10	in	in	ADP
fnp-3766	638	11	brain	brain	NOUN
fnp-3766	638	12	.	.	PUNCT
fnp-3766	639	1	brain	brain	NOUN
fnp-3766	639	2	.	.	PUNCT
fnp-3766	640	1	2013;136(pt	2013;136(pt	PROPN
fnp-3766	640	2	4):1128	4):1128	NUM
fnp-3766	640	3	-	-	PUNCT
fnp-3766	640	4	38	38	NUM
fnp-3766	640	5	.	.	PUNCT
fnp-3766	640	6	64	64	NUM
fnp-3766	640	7	.	.	PUNCT
fnp-3766	641	1	recasens	recasen	NOUN
fnp-3766	641	2	a	a	PRON
fnp-3766	641	3	,	,	PUNCT
fnp-3766	641	4	dehay	dehay	PROPN
fnp-3766	641	5	b	b	PROPN
fnp-3766	641	6	,	,	PUNCT
fnp-3766	641	7	bove	bove	PROPN
fnp-3766	641	8	j	j	PROPN
fnp-3766	641	9	,	,	PUNCT
fnp-3766	641	10	carballo	carballo	NOUN
fnp-3766	641	11	-	-	PUNCT
fnp-3766	641	12	carbajal	carbajal	NOUN
fnp-3766	642	1	i	i	NOUN
fnp-3766	642	2	,	,	PUNCT
fnp-3766	642	3	dovero	dovero	NOUN
fnp-3766	642	4	s	s	PROPN
fnp-3766	642	5	,	,	PUNCT
fnp-3766	642	6	perez	perez	PROPN
fnp-3766	642	7	-	-	PUNCT
fnp-3766	642	8	villalba	villalba	PROPN
fnp-3766	642	9	a	a	PRON
fnp-3766	642	10	,	,	PUNCT
fnp-3766	642	11	et	et	PROPN
fnp-3766	642	12	al	al	PROPN
fnp-3766	642	13	.	.	PROPN
fnp-3766	642	14	lewy	lewy	PROPN
fnp-3766	642	15	body	body	NOUN
fnp-3766	642	16	extracts	extract	NOUN
fnp-3766	642	17	from	from	ADP
fnp-3766	642	18	parkinson	parkinson	NOUN
fnp-3766	642	19	disease	disease	NOUN
fnp-3766	642	20	brains	brain	NOUN
fnp-3766	642	21	trigger	trigger	NOUN
fnp-3766	642	22	alpha	alpha	NOUN
fnp-3766	642	23	-	-	PUNCT
fnp-3766	642	24	synuclein	synuclein	NOUN
fnp-3766	642	25	pathology	pathology	NOUN
fnp-3766	642	26	and	and	CCONJ
fnp-3766	642	27	neurodegeneration	neurodegeneration	NOUN
fnp-3766	642	28	in	in	ADP
fnp-3766	642	29	mice	mouse	NOUN
fnp-3766	642	30	and	and	CCONJ
fnp-3766	642	31	monkeys	monkey	NOUN
fnp-3766	642	32	.	.	PUNCT
fnp-3766	643	1	ann	ann	PROPN
fnp-3766	643	2	neurol	neurol	PROPN
fnp-3766	643	3	.	.	PUNCT
fnp-3766	644	1	2014;75(3):351	2014;75(3):351	NUM
fnp-3766	644	2	-	-	PUNCT
fnp-3766	644	3	62	62	NUM
fnp-3766	644	4	.	.	PUNCT
fnp-3766	645	1	65	65	NUM
fnp-3766	645	2	.	.	PUNCT
fnp-3766	646	1	kane	kane	PROPN
fnp-3766	646	2	md	md	PROPN
fnp-3766	646	3	,	,	PUNCT
fnp-3766	646	4	lipinski	lipinski	PROPN
fnp-3766	646	5	wj	wj	PROPN
fnp-3766	646	6	,	,	PUNCT
fnp-3766	646	7	callahan	callahan	PROPN
fnp-3766	646	8	mj	mj	PROPN
fnp-3766	646	9	,	,	PUNCT
fnp-3766	646	10	bian	bian	PROPN
fnp-3766	646	11	f	f	PROPN
fnp-3766	646	12	,	,	PUNCT
fnp-3766	646	13	durham	durham	PROPN
fnp-3766	646	14	ra	ra	PROPN
fnp-3766	646	15	,	,	PUNCT
fnp-3766	646	16	schwarz	schwarz	PROPN
fnp-3766	646	17	rd	rd	PROPN
fnp-3766	646	18	,	,	PUNCT
fnp-3766	646	19	et	et	PROPN
fnp-3766	646	20	al	al	PROPN
fnp-3766	646	21	.	.	PROPN
fnp-3766	646	22	evidence	evidence	NOUN
fnp-3766	646	23	for	for	ADP
fnp-3766	646	24	seeding	seeding	NOUN
fnp-3766	646	25	of	of	ADP
fnp-3766	646	26	beta	beta	ADJ
fnp-3766	646	27	-amyloid	-amyloid	NOUN
fnp-3766	646	28	by	by	ADP
fnp-3766	646	29	intracerebral	intracerebral	ADJ
fnp-3766	646	30	infusion	infusion	NOUN
fnp-3766	646	31	of	of	ADP
fnp-3766	646	32	alzheimer	alzheimer	PROPN
fnp-3766	646	33	brain	brain	NOUN
fnp-3766	646	34	extracts	extract	NOUN
fnp-3766	646	35	in	in	ADP
fnp-3766	646	36	beta	beta	ADJ
fnp-3766	646	37	-amyloid	-amyloid	NOUN
fnp-3766	646	38	precursor	precursor	NOUN
fnp-3766	646	39	protein	protein	NOUN
fnp-3766	646	40	-	-	PUNCT
fnp-3766	646	41	transgenic	transgenic	NOUN
fnp-3766	646	42	mice	mouse	NOUN
fnp-3766	646	43	.	.	PUNCT
fnp-3766	647	1	j	j	PROPN
fnp-3766	647	2	neurosci	neurosci	PROPN
fnp-3766	647	3	.	.	PUNCT
fnp-3766	648	1	2000;20(10):3606	2000;20(10):3606	NUM
fnp-3766	648	2	-	-	SYM
fnp-3766	648	3	11	11	NUM
fnp-3766	648	4	.	.	PUNCT
fnp-3766	649	1	66	66	NUM
fnp-3766	649	2	.	.	PUNCT
fnp-3766	650	1	eisele	eisele	PROPN
fnp-3766	650	2	ys	ys	PROPN
fnp-3766	650	3	,	,	PUNCT
fnp-3766	650	4	obermuller	obermuller	NOUN
fnp-3766	650	5	u	u	NOUN
fnp-3766	650	6	,	,	PUNCT
fnp-3766	650	7	heilbronner	heilbronner	PROPN
fnp-3766	650	8	g	g	PROPN
fnp-3766	650	9	,	,	PUNCT
fnp-3766	650	10	baumann	baumann	PROPN
fnp-3766	650	11	f	f	PROPN
fnp-3766	650	12	,	,	PUNCT
fnp-3766	650	13	kaeser	kaeser	PROPN
fnp-3766	650	14	sa	sa	PROPN
fnp-3766	650	15	,	,	PUNCT
fnp-3766	650	16	wolburg	wolburg	PROPN
fnp-3766	650	17	h	h	NOUN
fnp-3766	650	18	,	,	PUNCT
fnp-3766	650	19	et	et	PROPN
fnp-3766	650	20	al	al	PROPN
fnp-3766	650	21	.	.	PROPN
fnp-3766	650	22	peripherally	peripherally	ADV
fnp-3766	650	23	applied	apply	VERB
fnp-3766	650	24	abeta	abeta	ADV
fnp-3766	650	25	-	-	PUNCT
fnp-3766	650	26	containing	contain	VERB
fnp-3766	650	27	inoculates	inoculate	NOUN
fnp-3766	650	28	induce	induce	VERB
fnp-3766	650	29	cerebral	cerebral	ADJ
fnp-3766	650	30	beta	beta	NOUN
fnp-3766	650	31	-	-	PUNCT
fnp-3766	650	32	amyloidosis	amyloidosis	NOUN
fnp-3766	650	33	.	.	PUNCT
fnp-3766	651	1	science	science	NOUN
fnp-3766	651	2	.	.	PUNCT
fnp-3766	652	1	2010;330(6006):980	2010;330(6006):980	NUM
fnp-3766	652	2	-	-	SYM
fnp-3766	652	3	2	2	NUM
fnp-3766	652	4	.	.	NUM
fnp-3766	652	5	67	67	NUM
fnp-3766	652	6	.	.	PUNCT
fnp-3766	653	1	saha	saha	PROPN
fnp-3766	653	2	j	j	PROPN
fnp-3766	653	3	,	,	PUNCT
fnp-3766	653	4	dean	dean	PROPN
fnp-3766	653	5	dn	dn	PROPN
fnp-3766	653	6	,	,	PUNCT
fnp-3766	653	7	dhakal	dhakal	PROPN
fnp-3766	653	8	s	s	PROPN
fnp-3766	653	9	,	,	PUNCT
fnp-3766	653	10	stockmal	stockmal	ADJ
fnp-3766	653	11	ka	ka	PROPN
fnp-3766	653	12	,	,	PUNCT
fnp-3766	653	13	morgan	morgan	PROPN
fnp-3766	653	14	se	se	PROPN
fnp-3766	653	15	,	,	PUNCT
fnp-3766	653	16	dillon	dillon	PROPN
fnp-3766	653	17	kd	kd	PROPN
fnp-3766	653	18	,	,	PUNCT
fnp-3766	653	19	et	et	PROPN
fnp-3766	653	20	al	al	PROPN
fnp-3766	653	21	.	.	PUNCT
fnp-3766	653	22	biophysical	biophysical	ADJ
fnp-3766	653	23	characteristics	characteristic	NOUN
fnp-3766	653	24	of	of	ADP
fnp-3766	653	25	lipid	lipid	NOUN
fnp-3766	653	26	-	-	PUNCT
fnp-3766	653	27	induced	induce	VERB
fnp-3766	653	28	abeta	abeta	NOUN
fnp-3766	653	29	oligomers	oligomer	NOUN
fnp-3766	653	30	correlate	correlate	VERB
fnp-3766	653	31	to	to	ADP
fnp-3766	653	32	distinctive	distinctive	ADJ
fnp-3766	653	33	phenotypes	phenotype	NOUN
fnp-3766	653	34	in	in	ADP
fnp-3766	653	35	transgenic	transgenic	NOUN
fnp-3766	653	36	mice	mouse	NOUN
fnp-3766	653	37	.	.	PUNCT
fnp-3766	654	1	faseb	faseb	PROPN
fnp-3766	654	2	j.	j.	PROPN
fnp-3766	654	3	2021;35(2):e21318	2021;35(2):e21318	PROPN
fnp-3766	654	4	.	.	PROPN
fnp-3766	655	1	68	68	NUM
fnp-3766	655	2	.	.	PUNCT
fnp-3766	656	1	preusser	preusser	PROPN
fnp-3766	656	2	m	m	PROPN
fnp-3766	656	3	,	,	PUNCT
fnp-3766	656	4	strobel	strobel	PROPN
fnp-3766	656	5	t	t	PROPN
fnp-3766	656	6	,	,	PUNCT
fnp-3766	656	7	gelpi	gelpi	NOUN
fnp-3766	656	8	e	e	NOUN
fnp-3766	656	9	,	,	PUNCT
fnp-3766	656	10	eiler	eiler	PROPN
fnp-3766	656	11	m	m	PROPN
fnp-3766	656	12	,	,	PUNCT
fnp-3766	656	13	broessner	broessner	NOUN
fnp-3766	656	14	g	g	NOUN
fnp-3766	656	15	,	,	PUNCT
fnp-3766	656	16	schmutzhard	schmutzhard	ADJ
fnp-3766	656	17	e	e	NOUN
fnp-3766	656	18	,	,	PUNCT
fnp-3766	656	19	et	et	PROPN
fnp-3766	656	20	al	al	PROPN
fnp-3766	656	21	.	.	PROPN
fnp-3766	656	22	alzheimer	alzheimer	PROPN
fnp-3766	656	23	-	-	PUNCT
fnp-3766	656	24	type	type	NOUN
fnp-3766	656	25	neuropathology	neuropathology	NOUN
fnp-3766	656	26	in	in	ADP
fnp-3766	656	27	a	a	DET
fnp-3766	656	28	28	28	NUM
fnp-3766	656	29	year	year	NOUN
fnp-3766	656	30	old	old	ADJ
fnp-3766	656	31	patient	patient	NOUN
fnp-3766	656	32	with	with	ADP
fnp-3766	656	33	iatrogenic	iatrogenic	ADJ
fnp-3766	656	34	creutzfeldt	creutzfeldt	ADJ
fnp-3766	656	35	-	-	PUNCT
fnp-3766	656	36	jakob	jakob	ADJ
fnp-3766	656	37	disease	disease	NOUN
fnp-3766	656	38	after	after	ADP
fnp-3766	656	39	dural	dural	ADJ
fnp-3766	656	40	grafting	grafting	NOUN
fnp-3766	656	41	.	.	PUNCT
fnp-3766	657	1	j	j	PROPN
fnp-3766	657	2	neurol	neurol	PROPN
fnp-3766	657	3	neurosurg	neurosurg	PROPN
fnp-3766	657	4	psychiatry	psychiatry	NOUN
fnp-3766	657	5	.	.	PUNCT
fnp-3766	658	1	2006;77(3):413	2006;77(3):413	NUM
fnp-3766	658	2	-	-	SYM
fnp-3766	658	3	6	6	NUM
fnp-3766	658	4	.	.	NOUN
fnp-3766	658	5	69	69	NUM
fnp-3766	658	6	.	.	PUNCT
fnp-3766	659	1	jaunmuktane	jaunmuktane	PROPN
fnp-3766	659	2	z	z	PROPN
fnp-3766	659	3	,	,	PUNCT
fnp-3766	659	4	mead	mead	PROPN
fnp-3766	659	5	s	s	PROPN
fnp-3766	659	6	,	,	PUNCT
fnp-3766	659	7	ellis	ellis	PROPN
fnp-3766	659	8	m	m	PROPN
fnp-3766	659	9	,	,	PUNCT
fnp-3766	659	10	wadsworth	wadsworth	PROPN
fnp-3766	659	11	jd	jd	PROPN
fnp-3766	659	12	,	,	PUNCT
fnp-3766	659	13	nicoll	nicoll	PROPN
fnp-3766	659	14	aj	aj	PROPN
fnp-3766	659	15	,	,	PUNCT
fnp-3766	659	16	kenny	kenny	PROPN
fnp-3766	659	17	j	j	PROPN
fnp-3766	659	18	,	,	PUNCT
fnp-3766	659	19	et	et	PROPN
fnp-3766	659	20	al	al	PROPN
fnp-3766	659	21	.	.	PROPN
fnp-3766	659	22	evidence	evidence	NOUN
fnp-3766	659	23	for	for	ADP
fnp-3766	659	24	human	human	ADJ
fnp-3766	659	25	transmission	transmission	NOUN
fnp-3766	659	26	of	of	ADP
fnp-3766	659	27	amyloid	amyloid	NOUN
fnp-3766	659	28	-	-	PUNCT
fnp-3766	659	29	beta	beta	NOUN
fnp-3766	659	30	pathology	pathology	NOUN
fnp-3766	659	31	and	and	CCONJ
fnp-3766	659	32	cerebral	cerebral	ADJ
fnp-3766	659	33	amyloid	amyloid	NOUN
fnp-3766	659	34	angiopathy	angiopathy	NOUN
fnp-3766	659	35	.	.	PUNCT
fnp-3766	660	1	nature	nature	NOUN
fnp-3766	660	2	.	.	PUNCT
fnp-3766	661	1	2015;525(7568):247	2015;525(7568):247	NUM
fnp-3766	661	2	-	-	SYM
fnp-3766	661	3	50	50	NUM
fnp-3766	661	4	.	.	PUNCT
fnp-3766	662	1	70	70	NUM
fnp-3766	662	2	.	.	PUNCT
fnp-3766	663	1	morales	morales	PROPN
fnp-3766	663	2	r	r	PROPN
fnp-3766	663	3	,	,	PUNCT
fnp-3766	663	4	duran	duran	NOUN
fnp-3766	663	5	-	-	PUNCT
fnp-3766	663	6	aniotz	aniotz	PROPN
fnp-3766	663	7	c	c	PROPN
fnp-3766	663	8	,	,	PUNCT
fnp-3766	663	9	castilla	castilla	PROPN
fnp-3766	663	10	j	j	PROPN
fnp-3766	663	11	,	,	PUNCT
fnp-3766	663	12	estrada	estrada	PROPN
fnp-3766	663	13	ld	ld	PROPN
fnp-3766	663	14	,	,	PUNCT
fnp-3766	663	15	soto	soto	PROPN
fnp-3766	663	16	c.	c.	PROPN
fnp-3766	663	17	de	de	PROPN
fnp-3766	663	18	novo	novo	PROPN
fnp-3766	663	19	induction	induction	NOUN
fnp-3766	663	20	of	of	ADP
fnp-3766	663	21	amyloid	amyloid	NOUN
fnp-3766	663	22	-	-	PUNCT
fnp-3766	663	23	beta	beta	NOUN
fnp-3766	663	24	deposition	deposition	NOUN
fnp-3766	663	25	in	in	ADP
fnp-3766	663	26	vivo	vivo	NOUN
fnp-3766	663	27	.	.	PUNCT
fnp-3766	664	1	mol	mol	ADP
fnp-3766	664	2	psychiatry	psychiatry	NOUN
fnp-3766	664	3	.	.	PUNCT
fnp-3766	665	1	2012;17(12):1347	2012;17(12):1347	NUM
fnp-3766	665	2	-	-	SYM
fnp-3766	665	3	53	53	NUM
fnp-3766	665	4	.	.	PUNCT
fnp-3766	666	1	71	71	NUM
fnp-3766	666	2	.	.	PUNCT
fnp-3766	667	1	fritschi	fritschi	VERB
fnp-3766	667	2	sk	sk	PROPN
fnp-3766	667	3	,	,	PUNCT
fnp-3766	667	4	langer	langer	PROPN
fnp-3766	667	5	f	f	PROPN
fnp-3766	667	6	,	,	PUNCT
fnp-3766	667	7	kaeser	kaeser	PROPN
fnp-3766	667	8	sa	sa	PROPN
fnp-3766	667	9	,	,	PUNCT
fnp-3766	667	10	maia	maia	PROPN
fnp-3766	667	11	lf	lf	PROPN
fnp-3766	667	12	,	,	PUNCT
fnp-3766	667	13	portelius	portelius	NOUN
fnp-3766	667	14	e	e	NOUN
fnp-3766	667	15	,	,	PUNCT
fnp-3766	667	16	pinotsi	pinotsi	PROPN
fnp-3766	667	17	d	d	PROPN
fnp-3766	667	18	,	,	PUNCT
fnp-3766	667	19	et	et	PROPN
fnp-3766	667	20	al	al	PROPN
fnp-3766	667	21	.	.	PUNCT
fnp-3766	668	1	highly	highly	ADV
fnp-3766	668	2	potent	potent	ADJ
fnp-3766	668	3	soluble	soluble	ADJ
fnp-3766	668	4	amyloid	amyloid	NOUN
fnp-3766	668	5	-	-	PUNCT
fnp-3766	668	6	beta	beta	NOUN
fnp-3766	668	7	seeds	seed	NOUN
fnp-3766	668	8	in	in	ADP
fnp-3766	668	9	human	human	ADJ
fnp-3766	668	10	alzheimer	alzheimer	PROPN
fnp-3766	668	11	brain	brain	NOUN
fnp-3766	668	12	but	but	CCONJ
fnp-3766	668	13	not	not	PART
fnp-3766	668	14	cerebrospinal	cerebrospinal	ADJ
fnp-3766	668	15	fluid	fluid	NOUN
fnp-3766	668	16	.	.	PUNCT
fnp-3766	669	1	brain	brain	NOUN
fnp-3766	669	2	.	.	PUNCT
fnp-3766	670	1	2014;137(pt	2014;137(pt	NUM
fnp-3766	670	2	11):2909	11):2909	NUM
fnp-3766	670	3	-	-	SYM
fnp-3766	670	4	15	15	NUM
fnp-3766	670	5	.	.	NOUN
fnp-3766	670	6	72	72	NUM
fnp-3766	670	7	.	.	PUNCT
fnp-3766	671	1	heilbronner	heilbronner	PROPN
fnp-3766	671	2	g	g	PROPN
fnp-3766	671	3	,	,	PUNCT
fnp-3766	671	4	eisele	eisele	PROPN
fnp-3766	671	5	ys	ys	PROPN
fnp-3766	671	6	,	,	PUNCT
fnp-3766	671	7	langer	langer	PROPN
fnp-3766	671	8	f	f	PROPN
fnp-3766	671	9	,	,	PUNCT
fnp-3766	671	10	kaeser	kaeser	PROPN
fnp-3766	671	11	sa	sa	PROPN
fnp-3766	671	12	,	,	PUNCT
fnp-3766	671	13	novotny	novotny	PROPN
fnp-3766	671	14	r	r	PROPN
fnp-3766	671	15	,	,	PUNCT
fnp-3766	671	16	nagarathinam	nagarathinam	NOUN
fnp-3766	672	1	a	a	NOUN
fnp-3766	672	2	,	,	PUNCT
fnp-3766	672	3	et	et	PROPN
fnp-3766	672	4	al	al	PROPN
fnp-3766	672	5	.	.	PROPN
fnp-3766	672	6	seeded	seed	VERB
fnp-3766	672	7	strain	strain	NOUN
fnp-3766	672	8	-	-	PUNCT
fnp-3766	672	9	like	like	ADJ
fnp-3766	672	10	transmission	transmission	NOUN
fnp-3766	672	11	of	of	ADP
fnp-3766	672	12	beta	beta	NOUN
fnp-3766	672	13	-	-	PUNCT
fnp-3766	672	14	amyloid	amyloid	NOUN
fnp-3766	672	15	morphotypes	morphotype	NOUN
fnp-3766	672	16	in	in	ADP
fnp-3766	672	17	app	app	NOUN
fnp-3766	672	18	transgenic	transgenic	NOUN
fnp-3766	672	19	mice	mouse	NOUN
fnp-3766	672	20	.	.	PUNCT
fnp-3766	673	1	embo	embo	PROPN
fnp-3766	673	2	rep	rep	PROPN
fnp-3766	673	3	.	.	PROPN
fnp-3766	673	4	2013;14(11):1017	2013;14(11):1017	NUM
fnp-3766	673	5	-	-	SYM
fnp-3766	673	6	22	22	NUM
fnp-3766	673	7	.	.	PUNCT
fnp-3766	674	1	73	73	NUM
fnp-3766	674	2	.	.	PUNCT
fnp-3766	675	1	eisele	eisele	PROPN
fnp-3766	675	2	ys	ys	VERB
fnp-3766	675	3	,	,	PUNCT
fnp-3766	675	4	fritschi	fritschi	VERB
fnp-3766	675	5	sk	sk	NOUN
fnp-3766	675	6	,	,	PUNCT
fnp-3766	675	7	hamaguchi	hamaguchi	PROPN
fnp-3766	675	8	t	t	PROPN
fnp-3766	675	9	,	,	PUNCT
fnp-3766	675	10	obermuller	obermuller	NOUN
fnp-3766	675	11	u	u	NOUN
fnp-3766	675	12	,	,	PUNCT
fnp-3766	675	13	fuger	fuger	VERB
fnp-3766	675	14	p	p	NOUN
fnp-3766	675	15	,	,	PUNCT
fnp-3766	675	16	skodras	skodras	PROPN
fnp-3766	675	17	a	a	X
fnp-3766	675	18	,	,	PUNCT
fnp-3766	675	19	et	et	PROPN
fnp-3766	675	20	al	al	PROPN
fnp-3766	675	21	.	.	PUNCT
fnp-3766	676	1	multiple	multiple	ADJ
fnp-3766	676	2	factors	factor	NOUN
fnp-3766	676	3	contribute	contribute	VERB
fnp-3766	676	4	to	to	ADP
fnp-3766	676	5	the	the	DET
fnp-3766	676	6	peripheral	peripheral	ADJ
fnp-3766	676	7	induction	induction	NOUN
fnp-3766	676	8	of	of	ADP
fnp-3766	676	9	cerebral	cerebral	ADJ
fnp-3766	676	10	beta	beta	NOUN
fnp-3766	676	11	-	-	PUNCT
fnp-3766	676	12	amyloidosis	amyloidosis	NOUN
fnp-3766	676	13	.	.	PUNCT
fnp-3766	677	1	j	j	PROPN
fnp-3766	677	2	neurosci	neurosci	PROPN
fnp-3766	677	3	.	.	PUNCT
fnp-3766	678	1	2014;34(31):10264	2014;34(31):10264	NUM
fnp-3766	678	2	-	-	SYM
fnp-3766	678	3	73	73	NUM
fnp-3766	678	4	.	.	PUNCT
fnp-3766	679	1	74	74	NUM
fnp-3766	679	2	.	.	PUNCT
fnp-3766	680	1	fritschi	fritschi	VERB
fnp-3766	680	2	sk	sk	PROPN
fnp-3766	680	3	,	,	PUNCT
fnp-3766	680	4	cintron	cintron	PROPN
fnp-3766	680	5	a	a	PROPN
fnp-3766	680	6	,	,	PUNCT
fnp-3766	680	7	ye	ye	PROPN
fnp-3766	680	8	l	l	NOUN
fnp-3766	680	9	,	,	PUNCT
fnp-3766	680	10	mahler	mahler	PROPN
fnp-3766	680	11	j	j	PROPN
fnp-3766	680	12	,	,	PUNCT
fnp-3766	680	13	buhler	buhler	PROPN
fnp-3766	680	14	a	a	PROPN
fnp-3766	680	15	,	,	PUNCT
fnp-3766	680	16	baumann	baumann	PROPN
fnp-3766	680	17	f	f	PROPN
fnp-3766	680	18	,	,	PUNCT
fnp-3766	680	19	et	et	PROPN
fnp-3766	680	20	al	al	PROPN
fnp-3766	680	21	.	.	PUNCT
fnp-3766	681	1	abeta	abeta	PROPN
fnp-3766	681	2	seeds	seed	NOUN
fnp-3766	681	3	resist	resist	VERB
fnp-3766	681	4	inactivation	inactivation	NOUN
fnp-3766	681	5	by	by	ADP
fnp-3766	681	6	formaldehyde	formaldehyde	NOUN
fnp-3766	681	7	.	.	PUNCT
fnp-3766	682	1	acta	acta	PROPN
fnp-3766	682	2	neuropathol	neuropathol	PROPN
fnp-3766	682	3	.	.	PUNCT
fnp-3766	683	1	2014;128(4):477	2014;128(4):477	NUM
fnp-3766	683	2	-	-	SYM
fnp-3766	683	3	84	84	NUM
fnp-3766	683	4	.	.	PUNCT
fnp-3766	684	1	75	75	NUM
fnp-3766	684	2	.	.	PUNCT
fnp-3766	685	1	ye	ye	NUM
fnp-3766	685	2	l	l	PROPN
fnp-3766	685	3	,	,	PUNCT
fnp-3766	685	4	rasmussen	rasmussen	PROPN
fnp-3766	685	5	j	j	PROPN
fnp-3766	685	6	,	,	PUNCT
fnp-3766	685	7	kaeser	kaeser	PROPN
fnp-3766	685	8	sa	sa	PROPN
fnp-3766	685	9	,	,	PUNCT
fnp-3766	685	10	marzesco	marzesco	PROPN
fnp-3766	685	11	am	am	PROPN
fnp-3766	685	12	,	,	PUNCT
fnp-3766	685	13	obermuller	obermuller	NOUN
fnp-3766	685	14	u	u	NOUN
fnp-3766	685	15	,	,	PUNCT
fnp-3766	685	16	mahler	mahler	PROPN
fnp-3766	685	17	j	j	PROPN
fnp-3766	685	18	,	,	PUNCT
fnp-3766	685	19	et	et	PROPN
fnp-3766	685	20	al	al	PROPN
fnp-3766	685	21	.	.	PUNCT
fnp-3766	686	1	abeta	abeta	PROPN
fnp-3766	686	2	seeding	seeding	NOUN
fnp-3766	686	3	potency	potency	NOUN
fnp-3766	686	4	peaks	peak	NOUN
fnp-3766	686	5	in	in	ADP
fnp-3766	686	6	the	the	DET
fnp-3766	686	7	early	early	ADJ
fnp-3766	686	8	stages	stage	NOUN
fnp-3766	686	9	of	of	ADP
fnp-3766	686	10	cerebral	cerebral	ADJ
fnp-3766	686	11	beta	beta	NOUN
fnp-3766	686	12	-	-	PUNCT
fnp-3766	686	13	amyloidosis	amyloidosis	NOUN
fnp-3766	686	14	.	.	PUNCT
fnp-3766	687	1	embo	embo	PROPN
fnp-3766	687	2	rep	rep	PROPN
fnp-3766	687	3	.	.	PROPN
fnp-3766	687	4	2017;18(9):1536	2017;18(9):1536	PROPN
fnp-3766	687	5	-	-	SYM
fnp-3766	687	6	44	44	NUM
fnp-3766	687	7	.	.	PUNCT
fnp-3766	688	1	76	76	NUM
fnp-3766	688	2	.	.	PUNCT
fnp-3766	689	1	kim	kim	PROPN
fnp-3766	689	2	j	j	PROPN
fnp-3766	689	3	,	,	PUNCT
fnp-3766	689	4	chakrabarty	chakrabarty	PROPN
fnp-3766	689	5	p	p	X
fnp-3766	689	6	,	,	PUNCT
fnp-3766	689	7	hanna	hanna	PROPN
fnp-3766	689	8	a	a	PRON
fnp-3766	689	9	,	,	PUNCT
fnp-3766	689	10	march	march	PROPN
fnp-3766	689	11	a	a	NOUN
fnp-3766	689	12	,	,	PUNCT
fnp-3766	689	13	dickson	dickson	PROPN
fnp-3766	689	14	dw	dw	PROPN
fnp-3766	689	15	,	,	PUNCT
fnp-3766	689	16	borchelt	borchelt	PROPN
fnp-3766	689	17	dr	dr	PROPN
fnp-3766	689	18	,	,	PUNCT
fnp-3766	689	19	et	et	PROPN
fnp-3766	689	20	al	al	PROPN
fnp-3766	689	21	.	.	PROPN
fnp-3766	689	22	normal	normal	ADJ
fnp-3766	689	23	cognition	cognition	NOUN
fnp-3766	689	24	in	in	ADP
fnp-3766	689	25	transgenic	transgenic	NOUN
fnp-3766	689	26	bri2	bri2	PROPN
fnp-3766	689	27	-	-	PUNCT
fnp-3766	689	28	abeta	abeta	NOUN
fnp-3766	689	29	mice	mouse	NOUN
fnp-3766	689	30	.	.	PUNCT
fnp-3766	690	1	mol	mol	ADP
fnp-3766	690	2	neurodegener	neurodegener	PROPN
fnp-3766	690	3	.	.	PUNCT
fnp-3766	691	1	2013;8:15	2013;8:15	NOUN
fnp-3766	691	2	.	.	PUNCT
fnp-3766	692	1	copyright	copyright	NOUN
fnp-3766	692	2	:	:	PUNCT
fnp-3766	692	3	©	©	PROPN
fnp-3766	692	4	2022	2022	NUM
fnp-3766	692	5	the	the	DET
fnp-3766	692	6	author(s	author(s	NOUN
fnp-3766	692	7	)	)	PUNCT
fnp-3766	692	8	.	.	PUNCT
fnp-3766	693	1	this	this	PRON
fnp-3766	693	2	is	be	AUX
fnp-3766	693	3	an	an	DET
fnp-3766	693	4	open	open	ADJ
fnp-3766	693	5	access	access	NOUN
fnp-3766	693	6	article	article	NOUN
fnp-3766	693	7	distributed	distribute	VERB
fnp-3766	693	8	under	under	ADP
fnp-3766	693	9	the	the	DET
fnp-3766	693	10	terms	term	NOUN
fnp-3766	693	11	of	of	ADP
fnp-3766	693	12	the	the	DET
fnp-3766	693	13	creative	creative	ADJ
fnp-3766	693	14	commons	common	NOUN
fnp-3766	693	15	attribution	attribution	NOUN
fnp-3766	693	16	4.0	4.0	NUM
fnp-3766	693	17	international	international	ADJ
fnp-3766	693	18	license	license	NOUN
fnp-3766	693	19	(	(	PUNCT
fnp-3766	693	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3766	693	21	)	)	PUNCT
fnp-3766	693	22	,	,	PUNCT
fnp-3766	693	23	which	which	PRON
fnp-3766	693	24	permits	permit	VERB
fnp-3766	693	25	unrestricted	unrestricted	ADJ
fnp-3766	693	26	use	use	NOUN
fnp-3766	693	27	,	,	PUNCT
fnp-3766	693	28	distribution	distribution	NOUN
fnp-3766	693	29	,	,	PUNCT
fnp-3766	693	30	and	and	CCONJ
fnp-3766	693	31	reproduction	reproduction	NOUN
fnp-3766	693	32	in	in	ADP
fnp-3766	693	33	any	any	DET
fnp-3766	693	34	medium	medium	NOUN
fnp-3766	693	35	,	,	PUNCT
fnp-3766	693	36	provided	provide	VERB
fnp-3766	693	37	the	the	DET
fnp-3766	693	38	original	original	ADJ
fnp-3766	693	39	author	author	NOUN
fnp-3766	693	40	and	and	CCONJ
fnp-3766	693	41	source	source	NOUN
fnp-3766	693	42	are	be	AUX
fnp-3766	693	43	credited	credit	VERB
fnp-3766	693	44	,	,	PUNCT
fnp-3766	693	45	a	a	DET
fnp-3766	693	46	link	link	NOUN
fnp-3766	693	47	to	to	ADP
fnp-3766	693	48	the	the	DET
fnp-3766	693	49	creative	creative	ADJ
fnp-3766	693	50	commons	common	NOUN
fnp-3766	693	51	license	license	NOUN
fnp-3766	693	52	is	be	AUX
fnp-3766	693	53	provided	provide	VERB
fnp-3766	693	54	,	,	PUNCT
fnp-3766	693	55	and	and	CCONJ
fnp-3766	693	56	any	any	DET
fnp-3766	693	57	changes	change	NOUN
fnp-3766	693	58	are	be	AUX
fnp-3766	693	59	indicated	indicate	VERB
fnp-3766	693	60	.	.	PUNCT
fnp-3766	694	1	the	the	DET
fnp-3766	694	2	creative	creative	ADJ
fnp-3766	694	3	commons	common	NOUN
fnp-3766	694	4	public	public	ADJ
fnp-3766	694	5	domain	domain	NOUN
fnp-3766	694	6	dedication	dedication	NOUN
fnp-3766	694	7	waiver	waiver	NOUN
fnp-3766	694	8	(	(	PUNCT
fnp-3766	694	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3766	694	10	)	)	PUNCT
fnp-3766	694	11	applies	apply	VERB
fnp-3766	694	12	to	to	ADP
fnp-3766	694	13	the	the	DET
fnp-3766	694	14	data	datum	NOUN
fnp-3766	694	15	made	make	VERB
fnp-3766	694	16	available	available	ADJ
fnp-3766	694	17	in	in	ADP
fnp-3766	694	18	this	this	DET
fnp-3766	694	19	article	article	NOUN
fnp-3766	694	20	,	,	PUNCT
fnp-3766	694	21	unless	unless	SCONJ
fnp-3766	694	22	otherwise	otherwise	ADV
fnp-3766	694	23	stated	state	VERB
fnp-3766	694	24	.	.	PUNCT