id	sid	tid	token	lemma	pos
fnp-3804	1	1	neurooncology	neurooncology	NOUN
fnp-3804	1	2	:	:	PUNCT
fnp-3804	1	3	2022	2022	NUM
fnp-3804	1	4	update	update	NOUN
fnp-3804	1	5	feel	feel	VERB
fnp-3804	1	6	free	free	ADJ
fnp-3804	1	7	to	to	PART
fnp-3804	1	8	add	add	VERB
fnp-3804	1	9	comments	comment	NOUN
fnp-3804	1	10	by	by	ADP
fnp-3804	1	11	clicking	click	VERB
fnp-3804	1	12	these	these	DET
fnp-3804	1	13	icons	icon	NOUN
fnp-3804	1	14	on	on	ADP
fnp-3804	1	15	the	the	DET
fnp-3804	1	16	sidebar	sidebar	NOUN
fnp-3804	1	17	free	free	ADJ
fnp-3804	1	18	neuropathology	neuropathology	NOUN
fnp-3804	1	19	3:4	3:4	NUM
fnp-3804	1	20	(	(	PUNCT
fnp-3804	1	21	2022	2022	NUM
fnp-3804	1	22	)	)	PUNCT
fnp-3804	1	23	review	review	VERB
fnp-3804	1	24	neurooncology	neurooncology	NOUN
fnp-3804	1	25	:	:	PUNCT
fnp-3804	1	26	2022	2022	NUM
fnp-3804	1	27	update	update	NOUN
fnp-3804	1	28	pieter	pieter	NOUN
fnp-3804	1	29	wesseling1,2	wesseling1,2	PROPN
fnp-3804	1	30	,	,	PUNCT
fnp-3804	1	31	jacob	jacob	PROPN
fnp-3804	1	32	s.	s.	PROPN
fnp-3804	1	33	rozowsky2	rozowsky2	PROPN
fnp-3804	2	1	1	1	NUM
fnp-3804	2	2	department	department	NOUN
fnp-3804	2	3	of	of	ADP
fnp-3804	2	4	pathology	pathology	PROPN
fnp-3804	2	5	,	,	PUNCT
fnp-3804	2	6	amsterdam	amsterdam	PROPN
fnp-3804	2	7	university	university	PROPN
fnp-3804	2	8	medical	medical	ADJ
fnp-3804	2	9	centers	center	NOUN
fnp-3804	2	10	/	/	SYM
fnp-3804	2	11	vumc	vumc	NOUN
fnp-3804	2	12	,	,	PUNCT
fnp-3804	2	13	brain	brain	NOUN
fnp-3804	2	14	tumor	tumor	NOUN
fnp-3804	2	15	center	center	PROPN
fnp-3804	2	16	amsterdam	amsterdam	PROPN
fnp-3804	2	17	,	,	PUNCT
fnp-3804	2	18	de	de	X
fnp-3804	2	19	boelelaan	boelelaan	NOUN
fnp-3804	2	20	1117	1117	NUM
fnp-3804	2	21	,	,	PUNCT
fnp-3804	2	22	1081hv	1081hv	ADJ
fnp-3804	2	23	amsterdam	amsterdam	PROPN
fnp-3804	2	24	,	,	PUNCT
fnp-3804	2	25	the	the	DET
fnp-3804	2	26	netherlands	netherlands	PROPN
fnp-3804	2	27	2	2	NUM
fnp-3804	2	28	laboratory	laboratory	NOUN
fnp-3804	2	29	for	for	ADP
fnp-3804	2	30	childhood	childhood	NOUN
fnp-3804	2	31	cancer	cancer	NOUN
fnp-3804	2	32	pathology	pathology	NOUN
fnp-3804	2	33	,	,	PUNCT
fnp-3804	2	34	princess	princess	NOUN
fnp-3804	2	35	máxima	máxima	PROPN
fnp-3804	2	36	center	center	PROPN
fnp-3804	2	37	for	for	ADP
fnp-3804	2	38	pediatric	pediatric	ADJ
fnp-3804	2	39	oncology	oncology	NOUN
fnp-3804	2	40	,	,	PUNCT
fnp-3804	2	41	heidelberglaan	heidelberglaan	NOUN
fnp-3804	2	42	25	25	NUM
fnp-3804	2	43	,	,	PUNCT
fnp-3804	2	44	3584	3584	NUM
fnp-3804	2	45	cs	cs	PROPN
fnp-3804	2	46	utrecht	utrecht	PROPN
fnp-3804	2	47	,	,	PUNCT
fnp-3804	2	48	the	the	DET
fnp-3804	2	49	netherlands	netherlands	PROPN
fnp-3804	2	50	corresponding	corresponding	ADJ
fnp-3804	2	51	author	author	NOUN
fnp-3804	2	52	:	:	PUNCT
fnp-3804	2	53	pieter	pieter	NOUN
fnp-3804	2	54	wesseling	wesseling	NOUN
fnp-3804	2	55	·	·	PUNCT
fnp-3804	2	56	department	department	NOUN
fnp-3804	2	57	of	of	ADP
fnp-3804	2	58	pathology	pathology	PROPN
fnp-3804	2	59	·	·	PUNCT
fnp-3804	2	60	amsterdam	amsterdam	PROPN
fnp-3804	2	61	university	university	PROPN
fnp-3804	2	62	medical	medical	ADJ
fnp-3804	2	63	centers	center	NOUN
fnp-3804	2	64	/	/	SYM
fnp-3804	2	65	vumc	vumc	NOUN
fnp-3804	2	66	·	·	PUNCT
fnp-3804	2	67	de	de	X
fnp-3804	2	68	boelelaan	boelelaan	PROPN
fnp-3804	2	69	1117	1117	NUM
fnp-3804	2	70	.	.	PUNCT
fnp-3804	3	1	1081	1081	NUM
fnp-3804	3	2	hv	hv	PROPN
fnp-3804	3	3	amsterdam	amsterdam	PROPN
fnp-3804	3	4	·	·	PUNCT
fnp-3804	3	5	the	the	DET
fnp-3804	3	6	netherlands	netherlands	PROPN
fnp-3804	3	7	p.wesseling@amsterdamumc.nl	p.wesseling@amsterdamumc.nl	VERB
fnp-3804	3	8	submitted	submit	VERB
fnp-3804	3	9	:	:	PUNCT
fnp-3804	3	10	14	14	NUM
fnp-3804	3	11	february	february	NOUN
fnp-3804	3	12	2022	2022	NUM
fnp-3804	3	13	accepted	accept	VERB
fnp-3804	3	14	:	:	PUNCT
fnp-3804	3	15	23	23	NUM
fnp-3804	3	16	february	february	NOUN
fnp-3804	3	17	2022	2022	NUM
fnp-3804	3	18	copyedited	copyedit	VERB
fnp-3804	3	19	by	by	ADP
fnp-3804	3	20	:	:	PUNCT
fnp-3804	3	21	henry	henry	PROPN
fnp-3804	3	22	robbert	robbert	PROPN
fnp-3804	3	23	published	publish	VERB
fnp-3804	3	24	:	:	PUNCT
fnp-3804	3	25	24	24	NUM
fnp-3804	3	26	february	february	PROPN
fnp-3804	3	27	2022	2022	NUM
fnp-3804	3	28	https://doi.org/10.17879/freeneuropathology-2022-3804	https://doi.org/10.17879/freeneuropathology-2022-3804	NOUN
fnp-3804	3	29	keywords	keyword	NOUN
fnp-3804	3	30	:	:	PUNCT
fnp-3804	3	31	brain	brain	NOUN
fnp-3804	3	32	tumor	tumor	NOUN
fnp-3804	3	33	,	,	PUNCT
fnp-3804	3	34	neuropathology	neuropathology	NOUN
fnp-3804	3	35	,	,	PUNCT
fnp-3804	3	36	molecular	molecular	ADJ
fnp-3804	3	37	diagnostics	diagnostic	NOUN
fnp-3804	3	38	,	,	PUNCT
fnp-3804	3	39	glioblastoma	glioblastoma	NOUN
fnp-3804	3	40	,	,	PUNCT
fnp-3804	3	41	medulloblastoma	medulloblastoma	ADJ
fnp-3804	3	42	abstract	abstract	NOUN
fnp-3804	3	43	this	this	DET
fnp-3804	3	44	‘	'	PUNCT
fnp-3804	3	45	neurooncology	neurooncology	NOUN
fnp-3804	3	46	:	:	PUNCT
fnp-3804	3	47	2022	2022	NUM
fnp-3804	3	48	update	update	NOUN
fnp-3804	3	49	’	'	PUNCT
fnp-3804	3	50	presents	present	VERB
fnp-3804	3	51	topics	topic	NOUN
fnp-3804	3	52	that	that	PRON
fnp-3804	3	53	were	be	AUX
fnp-3804	3	54	selected	select	VERB
fnp-3804	3	55	by	by	ADP
fnp-3804	3	56	the	the	DET
fnp-3804	3	57	authors	author	NOUN
fnp-3804	3	58	as	as	ADP
fnp-3804	3	59	top	top	ADJ
fnp-3804	3	60	ten	ten	NUM
fnp-3804	3	61	discoveries	discovery	NOUN
fnp-3804	3	62	published	publish	VERB
fnp-3804	3	63	in	in	ADP
fnp-3804	3	64	2021	2021	NUM
fnp-3804	3	65	in	in	ADP
fnp-3804	3	66	the	the	DET
fnp-3804	3	67	broader	broad	ADJ
fnp-3804	3	68	field	field	NOUN
fnp-3804	3	69	of	of	ADP
fnp-3804	3	70	neurooncological	neurooncological	ADJ
fnp-3804	3	71	pathology	pathology	NOUN
fnp-3804	3	72	.	.	PUNCT
fnp-3804	4	1	this	this	DET
fnp-3804	4	2	time	time	NOUN
fnp-3804	4	3	,	,	PUNCT
fnp-3804	4	4	the	the	DET
fnp-3804	4	5	spectrum	spectrum	NOUN
fnp-3804	4	6	of	of	ADP
fnp-3804	4	7	topics	topic	NOUN
fnp-3804	4	8	includes	include	VERB
fnp-3804	4	9	:	:	PUNCT
fnp-3804	4	10	papers	paper	NOUN
fnp-3804	4	11	with	with	ADP
fnp-3804	4	12	a	a	DET
fnp-3804	4	13	direct	direct	ADJ
fnp-3804	4	14	impact	impact	NOUN
fnp-3804	4	15	on	on	ADP
fnp-3804	4	16	daily	daily	ADJ
fnp-3804	4	17	diagnostic	diagnostic	ADJ
fnp-3804	4	18	practice	practice	NOUN
fnp-3804	4	19	of	of	ADP
fnp-3804	4	20	cns	cns	PROPN
fnp-3804	4	21	tumors	tumor	NOUN
fnp-3804	4	22	in	in	ADP
fnp-3804	4	23	general	general	ADJ
fnp-3804	4	24	and	and	CCONJ
fnp-3804	4	25	with	with	ADP
fnp-3804	4	26	information	information	NOUN
fnp-3804	4	27	on	on	ADP
fnp-3804	4	28	how	how	SCONJ
fnp-3804	4	29	to	to	PART
fnp-3804	4	30	improve	improve	VERB
fnp-3804	4	31	grading	grade	VERB
fnp-3804	4	32	of	of	ADP
fnp-3804	4	33	meningiomas	meningioma	NOUN
fnp-3804	4	34	;	;	PUNCT
fnp-3804	4	35	studies	study	NOUN
fnp-3804	4	36	shedding	shed	VERB
fnp-3804	4	37	new	new	ADJ
fnp-3804	4	38	light	light	NOUN
fnp-3804	4	39	on	on	ADP
fnp-3804	4	40	the	the	DET
fnp-3804	4	41	oncogenesis	oncogenesis	NOUN
fnp-3804	4	42	of	of	ADP
fnp-3804	4	43	gliomas	glioma	NOUN
fnp-3804	4	44	(	(	PUNCT
fnp-3804	4	45	in	in	ADP
fnp-3804	4	46	particular	particular	ADJ
fnp-3804	4	47	‘	'	PUNCT
fnp-3804	4	48	optic	optic	ADJ
fnp-3804	4	49	gliomas	glioma	NOUN
fnp-3804	4	50	’	'	PUNCT
fnp-3804	4	51	and	and	CCONJ
fnp-3804	4	52	h3	h3	NOUN
fnp-3804	4	53	-	-	PUNCT
fnp-3804	4	54	mutant	mutant	ADJ
fnp-3804	4	55	gliomas	glioma	NOUN
fnp-3804	4	56	)	)	PUNCT
fnp-3804	4	57	;	;	PUNCT
fnp-3804	4	58	several	several	ADJ
fnp-3804	4	59	‘	'	PUNCT
fnp-3804	4	60	multi	multi	ADJ
fnp-3804	4	61	-	-	ADJ
fnp-3804	4	62	omic	omic	ADJ
fnp-3804	4	63	’	'	PUNCT
fnp-3804	4	64	investigations	investigation	NOUN
fnp-3804	4	65	unraveling	unravel	VERB
fnp-3804	4	66	the	the	DET
fnp-3804	4	67	intra	intra	ADJ
fnp-3804	4	68	-	-	ADJ
fnp-3804	4	69	tumoral	tumoral	ADJ
fnp-3804	4	70	heterogeneity	heterogeneity	NOUN
fnp-3804	4	71	of	of	ADP
fnp-3804	4	72	especially	especially	ADV
fnp-3804	4	73	glioblastomas	glioblastoma	NOUN
fnp-3804	4	74	further	far	ADV
fnp-3804	4	75	;	;	PUNCT
fnp-3804	4	76	a	a	DET
fnp-3804	4	77	study	study	NOUN
fnp-3804	4	78	indicating	indicate	VERB
fnp-3804	4	79	the	the	DET
fnp-3804	4	80	potential	potential	NOUN
fnp-3804	4	81	of	of	ADP
fnp-3804	4	82	‘	'	PUNCT
fnp-3804	4	83	repurposing	repurpose	VERB
fnp-3804	4	84	’	'	PUNCT
fnp-3804	4	85	prozac	prozac	NOUN
fnp-3804	4	86	®	®	NOUN
fnp-3804	4	87	for	for	ADP
fnp-3804	4	88	the	the	DET
fnp-3804	4	89	treatment	treatment	NOUN
fnp-3804	4	90	of	of	ADP
fnp-3804	4	91	glioblastomas	glioblastoma	NOUN
fnp-3804	4	92	;	;	PUNCT
fnp-3804	4	93	liquid	liquid	ADJ
fnp-3804	4	94	biopsy	biopsy	NOUN
fnp-3804	4	95	using	use	VERB
fnp-3804	4	96	csf	csf	NOUN
fnp-3804	4	97	for	for	ADP
fnp-3804	4	98	assessment	assessment	NOUN
fnp-3804	4	99	of	of	ADP
fnp-3804	4	100	residual	residual	ADJ
fnp-3804	4	101	medulloblastoma	medulloblastoma	NOUN
fnp-3804	4	102	.	.	PUNCT
fnp-3804	5	1	in	in	ADP
fnp-3804	5	2	the	the	DET
fnp-3804	5	3	last	last	ADJ
fnp-3804	5	4	part	part	NOUN
fnp-3804	5	5	of	of	ADP
fnp-3804	5	6	this	this	DET
fnp-3804	5	7	review	review	NOUN
fnp-3804	5	8	some	some	DET
fnp-3804	5	9	other	other	ADJ
fnp-3804	5	10	papers	paper	NOUN
fnp-3804	5	11	are	be	AUX
fnp-3804	5	12	mentioned	mention	VERB
fnp-3804	5	13	that	that	PRON
fnp-3804	5	14	did	do	AUX
fnp-3804	5	15	n’t	not	PART
fnp-3804	5	16	make	make	VERB
fnp-3804	5	17	it	it	PRON
fnp-3804	5	18	to	to	ADP
fnp-3804	5	19	this	this	PRON
fnp-3804	5	20	(	(	PUNCT
fnp-3804	5	21	quite	quite	ADV
fnp-3804	5	22	subjective	subjective	ADJ
fnp-3804	5	23	)	)	PUNCT
fnp-3804	5	24	top	top	ADJ
fnp-3804	5	25	ten	ten	NUM
fnp-3804	5	26	list	list	NOUN
fnp-3804	5	27	.	.	PUNCT
fnp-3804	6	1	introduction	introduction	NOUN
fnp-3804	6	2	for	for	ADP
fnp-3804	6	3	the	the	DET
fnp-3804	6	4	third	third	ADJ
fnp-3804	6	5	year	year	NOUN
fnp-3804	6	6	in	in	ADP
fnp-3804	6	7	a	a	DET
fnp-3804	6	8	row	row	NOUN
fnp-3804	6	9	,	,	PUNCT
fnp-3804	6	10	the	the	DET
fnp-3804	6	11	first	first	ADJ
fnp-3804	6	12	author	author	NOUN
fnp-3804	6	13	of	of	ADP
fnp-3804	6	14	this	this	DET
fnp-3804	6	15	paper	paper	NOUN
fnp-3804	6	16	was	be	AUX
fnp-3804	6	17	invited	invite	VERB
fnp-3804	6	18	to	to	PART
fnp-3804	6	19	contribute	contribute	VERB
fnp-3804	6	20	a	a	DET
fnp-3804	6	21	review	review	NOUN
fnp-3804	6	22	on	on	ADP
fnp-3804	6	23	the	the	DET
fnp-3804	6	24	top	top	ADJ
fnp-3804	6	25	ten	ten	NUM
fnp-3804	6	26	discoveries	discovery	NOUN
fnp-3804	6	27	in	in	ADP
fnp-3804	6	28	neurooncology	neurooncology	NOUN
fnp-3804	6	29	published	publish	VERB
fnp-3804	6	30	in	in	ADP
fnp-3804	6	31	the	the	DET
fnp-3804	6	32	previous	previous	ADJ
fnp-3804	6	33	year	year	NOUN
fnp-3804	6	34	.	.	PUNCT
fnp-3804	7	1	rather	rather	ADV
fnp-3804	7	2	than	than	ADP
fnp-3804	7	3	checking	check	VERB
fnp-3804	7	4	over	over	ADP
fnp-3804	7	5	10,000	10,000	NUM
fnp-3804	7	6	papers	paper	NOUN
fnp-3804	7	7	on	on	ADP
fnp-3804	7	8	tumors	tumor	NOUN
fnp-3804	7	9	of	of	ADP
fnp-3804	7	10	the	the	DET
fnp-3804	7	11	central	central	ADJ
fnp-3804	7	12	nervous	nervous	ADJ
fnp-3804	7	13	system	system	NOUN
fnp-3804	7	14	(	(	PUNCT
fnp-3804	7	15	cns	cns	NOUN
fnp-3804	7	16	)	)	PUNCT
fnp-3804	7	17	published	publish	VERB
fnp-3804	7	18	in	in	ADP
fnp-3804	7	19	2021	2021	NUM
fnp-3804	7	20	(	(	PUNCT
fnp-3804	7	21	as	as	SCONJ
fnp-3804	7	22	was	be	AUX
fnp-3804	7	23	done	do	VERB
fnp-3804	7	24	for	for	ADP
fnp-3804	7	25	the	the	DET
fnp-3804	7	26	previous	previous	ADJ
fnp-3804	7	27	review	review	NOUN
fnp-3804	7	28	)	)	PUNCT
fnp-3804	7	29	,	,	PUNCT
fnp-3804	7	30	he	he	PRON
fnp-3804	7	31	now	now	ADV
fnp-3804	7	32	restricted	restrict	VERB
fnp-3804	7	33	himself	himself	PRON
fnp-3804	7	34	to	to	ADP
fnp-3804	7	35	screening	screen	VERB
fnp-3804	7	36	the	the	DET
fnp-3804	7	37	higher	higher	ADV
fnp-3804	7	38	-	-	PUNCT
fnp-3804	7	39	ranked	rank	VERB
fnp-3804	7	40	neurooncology	neurooncology	NOUN
fnp-3804	7	41	and	and	CCONJ
fnp-3804	7	42	neuropathology	neuropathology	NOUN
fnp-3804	7	43	journals	journal	NOUN
fnp-3804	7	44	and	and	CCONJ
fnp-3804	7	45	the	the	DET
fnp-3804	7	46	top	top	ADJ
fnp-3804	7	47	-	-	PUNCT
fnp-3804	7	48	journals	journal	NOUN
fnp-3804	7	49	in	in	ADP
fnp-3804	7	50	oncology	oncology	NOUN
fnp-3804	7	51	and	and	CCONJ
fnp-3804	7	52	science	science	NOUN
fnp-3804	7	53	with	with	ADP
fnp-3804	7	54	a	a	DET
fnp-3804	7	55	broader	broad	ADJ
fnp-3804	7	56	scope	scope	NOUN
fnp-3804	7	57	.	.	PUNCT
fnp-3804	8	1	furthermore	furthermore	ADV
fnp-3804	8	2	,	,	PUNCT
fnp-3804	8	3	he	he	PRON
fnp-3804	8	4	teamed	team	VERB
fnp-3804	8	5	up	up	ADP
fnp-3804	8	6	with	with	ADP
fnp-3804	8	7	the	the	DET
fnp-3804	8	8	last	last	ADJ
fnp-3804	8	9	author	author	NOUN
fnp-3804	8	10	,	,	PUNCT
fnp-3804	8	11	a	a	DET
fnp-3804	8	12	young	young	ADJ
fnp-3804	8	13	fulbright	fulbright	PROPN
fnp-3804	8	14	scholar	scholar	NOUN
fnp-3804	8	15	from	from	ADP
fnp-3804	8	16	the	the	DET
fnp-3804	8	17	usa	usa	PROPN
fnp-3804	8	18	that	that	SCONJ
fnp-3804	8	19	he	he	PRON
fnp-3804	8	20	supervises	supervise	VERB
fnp-3804	8	21	for	for	ADP
fnp-3804	8	22	a	a	DET
fnp-3804	8	23	period	period	NOUN
fnp-3804	8	24	of	of	ADP
fnp-3804	8	25	9	9	NUM
fnp-3804	8	26	months	month	NOUN
fnp-3804	8	27	in	in	ADP
fnp-3804	8	28	the	the	DET
fnp-3804	8	29	netherlands	netherlands	PROPN
fnp-3804	8	30	.	.	PUNCT
fnp-3804	9	1	the	the	DET
fnp-3804	9	2	last	last	ADJ
fnp-3804	9	3	author	author	NOUN
fnp-3804	9	4	mainly	mainly	ADV
fnp-3804	9	5	used	use	VERB
fnp-3804	9	6	a	a	DET
fnp-3804	9	7	twitter	twitter	NOUN
fnp-3804	9	8	®	®	NOUN
fnp-3804	9	9	-based	-base	VERB
fnp-3804	9	10	approach	approach	NOUN
fnp-3804	9	11	for	for	ADP
fnp-3804	9	12	identifying	identify	VERB
fnp-3804	9	13	promising	promise	VERB
fnp-3804	9	14	candidates	candidate	NOUN
fnp-3804	9	15	for	for	ADP
fnp-3804	9	16	our	our	PRON
fnp-3804	9	17	list	list	NOUN
fnp-3804	9	18	of	of	ADP
fnp-3804	9	19	top	top	ADJ
fnp-3804	9	20	ten	ten	NUM
fnp-3804	9	21	discoveries	discovery	NOUN
fnp-3804	9	22	in	in	ADP
fnp-3804	9	23	2021	2021	NUM
fnp-3804	9	24	.	.	PUNCT
fnp-3804	10	1	interestingly	interestingly	ADV
fnp-3804	10	2	,	,	PUNCT
fnp-3804	10	3	there	there	PRON
fnp-3804	10	4	was	be	VERB
fnp-3804	10	5	quite	quite	DET
fnp-3804	10	6	some	some	DET
fnp-3804	10	7	overlap	overlap	NOUN
fnp-3804	10	8	between	between	ADP
fnp-3804	10	9	the	the	DET
fnp-3804	10	10	results	result	NOUN
fnp-3804	10	11	of	of	ADP
fnp-3804	10	12	these	these	DET
fnp-3804	10	13	different	different	ADJ
fnp-3804	10	14	search	search	NOUN
fnp-3804	10	15	strategies	strategy	NOUN
fnp-3804	10	16	(	(	PUNCT
fnp-3804	10	17	but	but	CCONJ
fnp-3804	10	18	more	more	ADJ
fnp-3804	10	19	research	research	NOUN
fnp-3804	10	20	is	be	AUX
fnp-3804	10	21	needed	need	VERB
fnp-3804	10	22	for	for	ADP
fnp-3804	10	23	sorting	sort	VERB
fnp-3804	10	24	out	out	ADP
fnp-3804	10	25	if	if	SCONJ
fnp-3804	10	26	twitter	twitter	NOUN
fnp-3804	10	27	®	®	NOUN
fnp-3804	10	28	is	be	AUX
fnp-3804	10	29	a	a	DET
fnp-3804	10	30	reliable	reliable	ADJ
fnp-3804	10	31	source	source	NOUN
fnp-3804	10	32	of	of	ADP
fnp-3804	10	33	information	information	NOUN
fnp-3804	10	34	in	in	ADP
fnp-3804	10	35	this	this	DET
fnp-3804	10	36	respect	respect	NOUN
fnp-3804	10	37	,	,	PUNCT
fnp-3804	10	38	also	also	ADV
fnp-3804	10	39	because	because	SCONJ
fnp-3804	10	40	it	it	PRON
fnp-3804	10	41	appears	appear	VERB
fnp-3804	10	42	that	that	SCONJ
fnp-3804	10	43	in	in	ADP
fnp-3804	10	44	other	other	ADJ
fnp-3804	10	45	areas	area	NOUN
fnp-3804	10	46	of	of	ADP
fnp-3804	10	47	life	life	NOUN
fnp-3804	10	48	the	the	DET
fnp-3804	10	49	information	information	NOUN
fnp-3804	10	50	shared	share	VERB
fnp-3804	10	51	by	by	ADP
fnp-3804	10	52	tweets	tweet	NOUN
fnp-3804	10	53	can	can	AUX
fnp-3804	10	54	cause	cause	VERB
fnp-3804	10	55	chaos	chaos	NOUN
fnp-3804	10	56	rather	rather	ADV
fnp-3804	10	57	than	than	ADP
fnp-3804	10	58	order	order	NOUN
fnp-3804	10	59	)	)	PUNCT
fnp-3804	10	60	.	.	PUNCT
fnp-3804	11	1	the	the	DET
fnp-3804	11	2	final	final	ADJ
fnp-3804	11	3	list	list	NOUN
fnp-3804	11	4	of	of	ADP
fnp-3804	11	5	topics	topic	NOUN
fnp-3804	11	6	selected	select	VERB
fnp-3804	11	7	by	by	ADP
fnp-3804	11	8	the	the	DET
fnp-3804	11	9	authors	author	NOUN
fnp-3804	11	10	as	as	ADP
fnp-3804	11	11	very	very	ADV
fnp-3804	11	12	interesting	interesting	ADJ
fnp-3804	11	13	and/or	and/or	CCONJ
fnp-3804	11	14	very	very	ADV
fnp-3804	11	15	important	important	ADJ
fnp-3804	11	16	for	for	ADP
fnp-3804	11	17	the	the	DET
fnp-3804	11	18	broader	broad	ADJ
fnp-3804	11	19	field	field	NOUN
fnp-3804	11	20	of	of	ADP
fnp-3804	11	21	neurooncological	neurooncological	ADJ
fnp-3804	11	22	pathology	pathology	NOUN
fnp-3804	11	23	this	this	DET
fnp-3804	11	24	time	time	NOUN
fnp-3804	11	25	looks	look	VERB
fnp-3804	11	26	like	like	ADP
fnp-3804	11	27	this	this	PRON
fnp-3804	11	28	:	:	PUNCT
fnp-3804	11	29	who	who	PRON
fnp-3804	11	30	2021	2021	NUM
fnp-3804	11	31	classification	classification	NOUN
fnp-3804	11	32	of	of	ADP
fnp-3804	11	33	cns	cns	PROPN
fnp-3804	11	34	tumors	tumor	NOUN
fnp-3804	11	35	1	1	NUM
fnp-3804	11	36	glioma	glioma	NOUN
fnp-3804	11	37	driver	driver	NOUN
fnp-3804	11	38	mutations	mutation	NOUN
fnp-3804	11	39	in	in	ADP
fnp-3804	11	40	the	the	DET
fnp-3804	11	41	normal	normal	ADJ
fnp-3804	11	42	human	human	ADJ
fnp-3804	11	43	brain	brain	NOUN
fnp-3804	11	44	2	2	NUM
fnp-3804	11	45	neuronal	neuronal	ADJ
fnp-3804	11	46	activity	activity	NOUN
fnp-3804	11	47	-	-	PUNCT
fnp-3804	11	48	dependent	dependent	ADJ
fnp-3804	11	49	initiation	initiation	NOUN
fnp-3804	11	50	of	of	ADP
fnp-3804	11	51	nf1	nf1	NOUN
fnp-3804	11	52	-	-	PUNCT
fnp-3804	11	53	mutant	mutant	ADJ
fnp-3804	11	54	‘	'	PUNCT
fnp-3804	11	55	optic	optic	ADJ
fnp-3804	11	56	gliomas	glioma	NOUN
fnp-3804	11	57	’	'	PUNCT
fnp-3804	11	58	3	3	NUM
fnp-3804	11	59	oncogenic	oncogenic	ADJ
fnp-3804	11	60	role	role	NOUN
fnp-3804	11	61	of	of	ADP
fnp-3804	11	62	h3	h3	NOUN
fnp-3804	11	63	mutations	mutation	NOUN
fnp-3804	11	64	in	in	ADP
fnp-3804	11	65	histogenesis	histogenesis	ADJ
fnp-3804	11	66	context	context	NOUN
fnp-3804	11	67	4,5	4,5	NUM
fnp-3804	11	68	epigenomic	epigenomic	ADJ
fnp-3804	11	69	insights	insight	NOUN
fnp-3804	11	70	into	into	ADP
fnp-3804	11	71	glioma	glioma	NOUN
fnp-3804	11	72	cell	cell	NOUN
fnp-3804	11	73	differentiation	differentiation	NOUN
fnp-3804	11	74	and	and	CCONJ
fnp-3804	11	75	plasticity	plasticity	NOUN
fnp-3804	11	76	6,7	6,7	NUM
fnp-3804	11	77	proteogenomic	proteogenomic	ADJ
fnp-3804	11	78	and	and	CCONJ
fnp-3804	11	79	metabolomic	metabolomic	ADJ
fnp-3804	11	80	characterization	characterization	NOUN
fnp-3804	11	81	of	of	ADP
fnp-3804	11	82	glioblastomas	glioblastoma	NOUN
fnp-3804	11	83	8	8	NUM
fnp-3804	11	84	genomic	genomic	NOUN
fnp-3804	11	85	and	and	CCONJ
fnp-3804	11	86	immunologic	immunologic	ADJ
fnp-3804	11	87	heterogeneity	heterogeneity	NOUN
fnp-3804	11	88	of	of	ADP
fnp-3804	11	89	gliomas	glioma	NOUN
fnp-3804	11	90	and	and	CCONJ
fnp-3804	11	91	brain	brain	NOUN
fnp-3804	11	92	metastases	metastasis	NOUN
fnp-3804	11	93	9	9	NUM
fnp-3804	11	94	therapeutic	therapeutic	ADJ
fnp-3804	11	95	interference	interference	NOUN
fnp-3804	11	96	with	with	ADP
fnp-3804	11	97	glioblastoma	glioblastoma	NOUN
fnp-3804	11	98	cell	cell	NOUN
fnp-3804	11	99	membranes	membrane	NOUN
fnp-3804	11	100	using	use	VERB
fnp-3804	11	101	prozac	prozac	NOUN
fnp-3804	11	102	®	®	NOUN
fnp-3804	11	103	10	10	NUM
fnp-3804	11	104	liquid	liquid	ADJ
fnp-3804	11	105	biopsy	biopsy	NOUN
fnp-3804	11	106	assessment	assessment	NOUN
fnp-3804	11	107	of	of	ADP
fnp-3804	11	108	residual	residual	ADJ
fnp-3804	11	109	medulloblastoma	medulloblastoma	NOUN
fnp-3804	11	110	11	11	NUM
fnp-3804	11	111	improved	improve	VERB
fnp-3804	11	112	‘	'	PUNCT
fnp-3804	11	113	histomolecular	histomolecular	ADJ
fnp-3804	11	114	’	'	PUNCT
fnp-3804	11	115	grading	grading	NOUN
fnp-3804	11	116	of	of	ADP
fnp-3804	11	117	meningiomas	meningiomas	PROPN
fnp-3804	11	118	12	12	NUM
fnp-3804	11	119	-	-	SYM
fnp-3804	11	120	14	14	NUM
fnp-3804	11	121	of	of	ADP
fnp-3804	11	122	note	note	NOUN
fnp-3804	11	123	,	,	PUNCT
fnp-3804	11	124	all	all	DET
fnp-3804	11	125	the	the	DET
fnp-3804	11	126	papers	paper	NOUN
fnp-3804	11	127	just	just	ADV
fnp-3804	11	128	mentioned	mention	VERB
fnp-3804	11	129	became	become	VERB
fnp-3804	11	130	officially	officially	ADV
fnp-3804	11	131	available	available	ADJ
fnp-3804	11	132	in	in	ADP
fnp-3804	11	133	2021	2021	NUM
fnp-3804	11	134	,	,	PUNCT
fnp-3804	11	135	but	but	CCONJ
fnp-3804	11	136	the	the	DET
fnp-3804	11	137	printed	print	VERB
fnp-3804	11	138	version	version	NOUN
fnp-3804	11	139	may	may	AUX
fnp-3804	11	140	have	have	AUX
fnp-3804	11	141	lagged	lag	VERB
fnp-3804	11	142	somewhat	somewhat	ADV
fnp-3804	11	143	behind	behind	ADV
fnp-3804	11	144	.	.	PUNCT
fnp-3804	12	1	also	also	ADV
fnp-3804	12	2	,	,	PUNCT
fnp-3804	12	3	and	and	CCONJ
fnp-3804	12	4	like	like	INTJ
fnp-3804	12	5	in	in	ADP
fnp-3804	12	6	previous	previous	ADJ
fnp-3804	12	7	years	year	NOUN
fnp-3804	12	8	,	,	PUNCT
fnp-3804	12	9	one	one	PRON
fnp-3804	12	10	has	have	VERB
fnp-3804	12	11	to	to	PART
fnp-3804	12	12	realize	realize	VERB
fnp-3804	12	13	that	that	SCONJ
fnp-3804	12	14	there	there	PRON
fnp-3804	12	15	is	be	VERB
fnp-3804	12	16	of	of	ADP
fnp-3804	12	17	course	course	NOUN
fnp-3804	12	18	quite	quite	DET
fnp-3804	12	19	a	a	DET
fnp-3804	12	20	subjective	subjective	ADJ
fnp-3804	12	21	component	component	NOUN
fnp-3804	12	22	in	in	ADP
fnp-3804	12	23	the	the	DET
fnp-3804	12	24	selection	selection	NOUN
fnp-3804	12	25	process	process	NOUN
fnp-3804	12	26	that	that	PRON
fnp-3804	12	27	resulted	result	VERB
fnp-3804	12	28	in	in	ADP
fnp-3804	12	29	this	this	DET
fnp-3804	12	30	list	list	NOUN
fnp-3804	12	31	.	.	PUNCT
fnp-3804	13	1	for	for	ADP
fnp-3804	13	2	example	example	NOUN
fnp-3804	13	3	,	,	PUNCT
fnp-3804	13	4	the	the	DET
fnp-3804	13	5	strong	strong	ADJ
fnp-3804	13	6	interest	interest	NOUN
fnp-3804	13	7	of	of	ADP
fnp-3804	13	8	the	the	DET
fnp-3804	13	9	last	last	ADJ
fnp-3804	13	10	author	author	NOUN
fnp-3804	13	11	in	in	ADP
fnp-3804	13	12	computational	computational	ADJ
fnp-3804	13	13	biology	biology	NOUN
fnp-3804	13	14	aspects	aspect	NOUN
fnp-3804	13	15	of	of	ADP
fnp-3804	13	16	cns	cns	PROPN
fnp-3804	13	17	tumors	tumor	NOUN
fnp-3804	13	18	may	may	AUX
fnp-3804	13	19	well	well	ADV
fnp-3804	13	20	have	have	AUX
fnp-3804	13	21	played	play	VERB
fnp-3804	13	22	a	a	DET
fnp-3804	13	23	role	role	NOUN
fnp-3804	13	24	in	in	ADP
fnp-3804	13	25	the	the	DET
fnp-3804	13	26	selection	selection	NOUN
fnp-3804	13	27	of	of	ADP
fnp-3804	13	28	topics	topic	NOUN
fnp-3804	13	29	5	5	NUM
fnp-3804	13	30	and	and	CCONJ
fnp-3804	13	31	6	6	NUM
fnp-3804	13	32	especially	especially	ADV
fnp-3804	13	33	.	.	PUNCT
fnp-3804	14	1	to	to	PART
fnp-3804	14	2	make	make	VERB
fnp-3804	14	3	up	up	ADP
fnp-3804	14	4	to	to	ADP
fnp-3804	14	5	some	some	DET
fnp-3804	14	6	degree	degree	NOUN
fnp-3804	14	7	for	for	ADP
fnp-3804	14	8	this	this	DET
fnp-3804	14	9	rather	rather	ADV
fnp-3804	14	10	subjectively	subjectively	ADV
fnp-3804	14	11	composed	compose	VERB
fnp-3804	14	12	bouquet	bouquet	NOUN
fnp-3804	14	13	of	of	ADP
fnp-3804	14	14	papers	paper	NOUN
fnp-3804	14	15	,	,	PUNCT
fnp-3804	14	16	in	in	ADP
fnp-3804	14	17	the	the	DET
fnp-3804	14	18	discussion	discussion	NOUN
fnp-3804	14	19	section	section	NOUN
fnp-3804	14	20	of	of	ADP
fnp-3804	14	21	this	this	DET
fnp-3804	14	22	review	review	NOUN
fnp-3804	14	23	some	some	DET
fnp-3804	14	24	papers	paper	NOUN
fnp-3804	14	25	/	/	SYM
fnp-3804	14	26	topics	topic	NOUN
fnp-3804	14	27	are	be	AUX
fnp-3804	14	28	mentioned	mention	VERB
fnp-3804	14	29	that	that	PRON
fnp-3804	14	30	did	do	AUX
fnp-3804	14	31	n’t	not	PART
fnp-3804	14	32	make	make	VERB
fnp-3804	14	33	it	it	PRON
fnp-3804	14	34	to	to	ADP
fnp-3804	14	35	this	this	DET
fnp-3804	14	36	top	top	ADJ
fnp-3804	14	37	ten	ten	NUM
fnp-3804	14	38	list	list	NOUN
fnp-3804	14	39	but	but	CCONJ
fnp-3804	14	40	that	that	PRON
fnp-3804	14	41	certainly	certainly	ADV
fnp-3804	14	42	are	be	AUX
fnp-3804	14	43	interesting	interesting	ADJ
fnp-3804	14	44	as	as	ADV
fnp-3804	14	45	well	well	ADV
fnp-3804	14	46	.	.	PUNCT
fnp-3804	15	1	hopefully	hopefully	ADV
fnp-3804	15	2	,	,	PUNCT
fnp-3804	15	3	this	this	DET
fnp-3804	15	4	review	review	NOUN
fnp-3804	15	5	thereby	thereby	ADV
fnp-3804	15	6	again	again	ADV
fnp-3804	15	7	helps	help	VERB
fnp-3804	15	8	to	to	PART
fnp-3804	15	9	appreciate	appreciate	VERB
fnp-3804	15	10	the	the	DET
fnp-3804	15	11	wealth	wealth	NOUN
fnp-3804	15	12	of	of	ADP
fnp-3804	15	13	(	(	PUNCT
fnp-3804	15	14	sometimes	sometimes	ADV
fnp-3804	15	15	mind	mind	NOUN
fnp-3804	15	16	-	-	PUNCT
fnp-3804	15	17	boggling	boggling	ADJ
fnp-3804	15	18	)	)	PUNCT
fnp-3804	15	19	information	information	NOUN
fnp-3804	15	20	provided	provide	VERB
fnp-3804	15	21	by	by	ADP
fnp-3804	15	22	the	the	DET
fnp-3804	15	23	papers	paper	NOUN
fnp-3804	15	24	that	that	PRON
fnp-3804	15	25	were	be	AUX
fnp-3804	15	26	used	use	VERB
fnp-3804	15	27	as	as	ADP
fnp-3804	15	28	building	build	VERB
fnp-3804	15	29	blocks	block	NOUN
fnp-3804	15	30	for	for	ADP
fnp-3804	15	31	the	the	DET
fnp-3804	15	32	present	present	ADJ
fnp-3804	15	33	manuscript	manuscript	NOUN
fnp-3804	15	34	.	.	PUNCT
fnp-3804	16	1	topic	topic	NOUN
fnp-3804	16	2	1	1	NUM
fnp-3804	16	3	:	:	PUNCT
fnp-3804	16	4	who	who	PRON
fnp-3804	16	5	2021	2021	NUM
fnp-3804	16	6	classification	classification	NOUN
fnp-3804	16	7	of	of	ADP
fnp-3804	16	8	cns	cns	PROPN
fnp-3804	16	9	tumors	tumor	NOUN
fnp-3804	16	10	1	1	NUM
fnp-3804	16	11	publication	publication	NOUN
fnp-3804	16	12	of	of	ADP
fnp-3804	16	13	a	a	DET
fnp-3804	16	14	new	new	ADJ
fnp-3804	16	15	who	who	PRON
fnp-3804	16	16	cns	cns	VERB
fnp-3804	16	17	tumor	tumor	NOUN
fnp-3804	16	18	classification	classification	NOUN
fnp-3804	16	19	may	may	AUX
fnp-3804	16	20	in	in	ADP
fnp-3804	16	21	itself	itself	PRON
fnp-3804	16	22	not	not	PART
fnp-3804	16	23	be	be	AUX
fnp-3804	16	24	perceived	perceive	VERB
fnp-3804	16	25	as	as	ADP
fnp-3804	16	26	a	a	DET
fnp-3804	16	27	major	major	ADJ
fnp-3804	16	28	scientific	scientific	ADJ
fnp-3804	16	29	achievement	achievement	NOUN
fnp-3804	16	30	.	.	PUNCT
fnp-3804	17	1	however	however	ADV
fnp-3804	17	2	,	,	PUNCT
fnp-3804	17	3	quite	quite	DET
fnp-3804	17	4	some	some	PRON
fnp-3804	17	5	of	of	ADP
fnp-3804	17	6	the	the	DET
fnp-3804	17	7	changes	change	NOUN
fnp-3804	17	8	implemented	implement	VERB
fnp-3804	17	9	in	in	ADP
fnp-3804	17	10	the	the	DET
fnp-3804	17	11	fifth	fifth	ADJ
fnp-3804	17	12	edition	edition	NOUN
fnp-3804	17	13	of	of	ADP
fnp-3804	17	14	the	the	PRON
fnp-3804	17	15	who	who	PRON
fnp-3804	17	16	classification	classification	NOUN
fnp-3804	17	17	of	of	ADP
fnp-3804	17	18	tumors	tumor	NOUN
fnp-3804	17	19	of	of	ADP
fnp-3804	17	20	the	the	DET
fnp-3804	17	21	central	central	ADJ
fnp-3804	17	22	nervous	nervous	ADJ
fnp-3804	17	23	system	system	NOUN
fnp-3804	17	24	(	(	PUNCT
fnp-3804	17	25	who	who	PRON
fnp-3804	17	26	cns5	cns5	VERB
fnp-3804	17	27	classification	classification	NOUN
fnp-3804	17	28	)	)	PUNCT
fnp-3804	17	29	are	be	AUX
fnp-3804	17	30	the	the	DET
fnp-3804	17	31	result	result	NOUN
fnp-3804	17	32	of	of	ADP
fnp-3804	17	33	very	very	ADV
fnp-3804	17	34	good	good	ADJ
fnp-3804	17	35	science	science	NOUN
fnp-3804	17	36	,	,	PUNCT
fnp-3804	17	37	followed	follow	VERB
fnp-3804	17	38	by	by	ADP
fnp-3804	17	39	(	(	PUNCT
fnp-3804	17	40	hopefully	hopefully	ADV
fnp-3804	17	41	)	)	PUNCT
fnp-3804	17	42	‘	'	PUNCT
fnp-3804	17	43	smart	smart	ADJ
fnp-3804	17	44	translation	translation	NOUN
fnp-3804	17	45	’	'	PUNCT
fnp-3804	17	46	of	of	ADP
fnp-3804	17	47	the	the	DET
fnp-3804	17	48	findings	finding	NOUN
fnp-3804	17	49	into	into	ADP
fnp-3804	17	50	a	a	DET
fnp-3804	17	51	new	new	ADJ
fnp-3804	17	52	classification	classification	NOUN
fnp-3804	17	53	,	,	PUNCT
fnp-3804	17	54	which	which	PRON
fnp-3804	17	55	definitely	definitely	ADV
fnp-3804	17	56	has	have	VERB
fnp-3804	17	57	a	a	DET
fnp-3804	17	58	major	major	ADJ
fnp-3804	17	59	impact	impact	NOUN
fnp-3804	17	60	on	on	ADP
fnp-3804	17	61	clinical	clinical	ADJ
fnp-3804	17	62	neurooncology	neurooncology	NOUN
fnp-3804	17	63	.	.	PUNCT
fnp-3804	18	1	since	since	SCONJ
fnp-3804	18	2	november	november	PROPN
fnp-3804	18	3	2021	2021	NUM
fnp-3804	18	4	,	,	PUNCT
fnp-3804	18	5	the	the	DET
fnp-3804	18	6	who	who	PRON
fnp-3804	18	7	cns5	cns5	PROPN
fnp-3804	18	8	classification	classification	NOUN
fnp-3804	18	9	is	be	AUX
fnp-3804	18	10	available	available	ADJ
fnp-3804	18	11	online	online	ADV
fnp-3804	18	12	via	via	ADP
fnp-3804	18	13	https://tumourclassification.iarc.who.int	https://tumourclassification.iarc.who.int	NOUN
fnp-3804	18	14	,	,	PUNCT
fnp-3804	18	15	and	and	CCONJ
fnp-3804	18	16	the	the	DET
fnp-3804	18	17	printed	print	VERB
fnp-3804	18	18	‘	'	PUNCT
fnp-3804	18	19	blue	blue	ADJ
fnp-3804	18	20	book	book	NOUN
fnp-3804	18	21	’	'	PUNCT
fnp-3804	18	22	version	version	NOUN
fnp-3804	18	23	can	can	AUX
fnp-3804	18	24	now	now	ADV
fnp-3804	18	25	be	be	AUX
fnp-3804	18	26	purchased	purchase	VERB
fnp-3804	18	27	as	as	ADV
fnp-3804	18	28	well	well	ADV
fnp-3804	18	29	(	(	PUNCT
fnp-3804	18	30	figure	figure	NOUN
fnp-3804	18	31	1	1	NUM
fnp-3804	18	32	)	)	PUNCT
fnp-3804	18	33	.	.	PUNCT
fnp-3804	19	1	the	the	DET
fnp-3804	19	2	review	review	NOUN
fnp-3804	19	3	by	by	ADP
fnp-3804	19	4	louis	louis	PROPN
fnp-3804	19	5	dn	dn	PROPN
fnp-3804	19	6	et	et	PROPN
fnp-3804	19	7	al	al	PROPN
fnp-3804	19	8	.	.	PROPN
fnp-3804	19	9	published	publish	VERB
fnp-3804	19	10	in	in	ADP
fnp-3804	19	11	neuro	neuro	NOUN
fnp-3804	19	12	-	-	PUNCT
fnp-3804	19	13	oncology	oncology	NOUN
fnp-3804	19	14	provides	provide	VERB
fnp-3804	19	15	a	a	DET
fnp-3804	19	16	very	very	ADV
fnp-3804	19	17	informative	informative	ADJ
fnp-3804	19	18	summary	summary	NOUN
fnp-3804	19	19	of	of	ADP
fnp-3804	19	20	major	major	ADJ
fnp-3804	19	21	general	general	ADJ
fnp-3804	19	22	changes	change	NOUN
fnp-3804	19	23	in	in	ADP
fnp-3804	19	24	the	the	PRON
fnp-3804	19	25	who	who	PRON
fnp-3804	19	26	cns5	cns5	VERB
fnp-3804	19	27	classification	classification	NOUN
fnp-3804	19	28	and	and	CCONJ
fnp-3804	19	29	of	of	ADP
fnp-3804	19	30	specific	specific	ADJ
fnp-3804	19	31	changes	change	NOUN
fnp-3804	19	32	in	in	ADP
fnp-3804	19	33	the	the	DET
fnp-3804	19	34	different	different	ADJ
fnp-3804	19	35	taxonomic	taxonomic	ADJ
fnp-3804	19	36	categories	category	NOUN
fnp-3804	19	37	1	1	NUM
fnp-3804	19	38	.	.	PUNCT
fnp-3804	19	39	figure	figure	NOUN
fnp-3804	19	40	1	1	NUM
fnp-3804	19	41	.	.	PUNCT
fnp-3804	20	1	covers	cover	NOUN
fnp-3804	20	2	of	of	ADP
fnp-3804	20	3	the	the	PRON
fnp-3804	20	4	who	who	PRON
fnp-3804	20	5	cns	cns	VERB
fnp-3804	20	6	tumor	tumor	NOUN
fnp-3804	20	7	blue	blue	ADJ
fnp-3804	20	8	books	book	NOUN
fnp-3804	20	9	throughout	throughout	ADP
fnp-3804	20	10	the	the	DET
fnp-3804	20	11	years.in	years.in	NOUN
fnp-3804	20	12	these	these	DET
fnp-3804	20	13	blue	blue	ADJ
fnp-3804	20	14	books	book	NOUN
fnp-3804	20	15	,	,	PUNCT
fnp-3804	20	16	the	the	DET
fnp-3804	20	17	actual	actual	ADJ
fnp-3804	20	18	who	who	PRON
fnp-3804	20	19	cns	cns	VERB
fnp-3804	20	20	tumor	tumor	NOUN
fnp-3804	20	21	classification	classification	NOUN
fnp-3804	20	22	is	be	AUX
fnp-3804	20	23	the	the	DET
fnp-3804	20	24	list	list	NOUN
fnp-3804	20	25	of	of	ADP
fnp-3804	20	26	tumors	tumor	NOUN
fnp-3804	20	27	that	that	PRON
fnp-3804	20	28	are	be	AUX
fnp-3804	20	29	recognized	recognize	VERB
fnp-3804	20	30	as	as	ADP
fnp-3804	20	31	distinct	distinct	ADJ
fnp-3804	20	32	tumor	tumor	NOUN
fnp-3804	20	33	types	type	NOUN
fnp-3804	20	34	(	(	PUNCT
fnp-3804	20	35	see	see	VERB
fnp-3804	20	36	e.g.	e.g.	ADV
fnp-3804	20	37	table	table	NOUN
fnp-3804	20	38	1	1	NUM
fnp-3804	20	39	for	for	ADP
fnp-3804	20	40	the	the	DET
fnp-3804	20	41	5th	5th	ADJ
fnp-3804	20	42	edition	edition	NOUN
fnp-3804	20	43	)	)	PUNCT
fnp-3804	20	44	;	;	PUNCT
fnp-3804	20	45	the	the	DET
fnp-3804	20	46	rest	rest	NOUN
fnp-3804	20	47	of	of	ADP
fnp-3804	20	48	the	the	DET
fnp-3804	20	49	information	information	NOUN
fnp-3804	20	50	in	in	ADP
fnp-3804	20	51	these	these	DET
fnp-3804	20	52	books	book	NOUN
fnp-3804	20	53	concerns	concern	NOUN
fnp-3804	20	54	explanation	explanation	NOUN
fnp-3804	20	55	of	of	ADP
fnp-3804	20	56	the	the	DET
fnp-3804	20	57	pathological	pathological	ADJ
fnp-3804	20	58	(	(	PUNCT
fnp-3804	20	59	nowadays	nowadays	ADV
fnp-3804	20	60	histological	histological	ADJ
fnp-3804	20	61	and	and	CCONJ
fnp-3804	20	62	molecular	molecular	ADJ
fnp-3804	20	63	)	)	PUNCT
fnp-3804	20	64	characteristics	characteristic	NOUN
fnp-3804	20	65	of	of	ADP
fnp-3804	20	66	these	these	DET
fnp-3804	20	67	tumors	tumor	NOUN
fnp-3804	20	68	,	,	PUNCT
fnp-3804	20	69	and	and	CCONJ
fnp-3804	20	70	the	the	DET
fnp-3804	20	71	most	most	ADV
fnp-3804	20	72	salient	salient	ADJ
fnp-3804	20	73	information	information	NOUN
fnp-3804	20	74	on	on	ADP
fnp-3804	20	75	their	their	PRON
fnp-3804	20	76	clinical	clinical	ADJ
fnp-3804	20	77	and	and	CCONJ
fnp-3804	20	78	radiological	radiological	ADJ
fnp-3804	20	79	context	context	NOUN
fnp-3804	20	80	.	.	PUNCT
fnp-3804	21	1	molecular	molecular	ADJ
fnp-3804	21	2	characteristics	characteristic	NOUN
fnp-3804	21	3	were	be	AUX
fnp-3804	21	4	for	for	ADP
fnp-3804	21	5	the	the	DET
fnp-3804	21	6	first	first	ADJ
fnp-3804	21	7	time	time	NOUN
fnp-3804	21	8	introduced	introduce	VERB
fnp-3804	21	9	as	as	ADP
fnp-3804	21	10	defining	define	VERB
fnp-3804	21	11	criteria	criterion	NOUN
fnp-3804	21	12	in	in	ADP
fnp-3804	21	13	the	the	DET
fnp-3804	21	14	revised	revised	ADJ
fnp-3804	21	15	4th	4th	ADJ
fnp-3804	21	16	edition	edition	NOUN
fnp-3804	21	17	,	,	PUNCT
fnp-3804	21	18	especially	especially	ADV
fnp-3804	21	19	for	for	ADP
fnp-3804	21	20	diffuse	diffuse	ADJ
fnp-3804	21	21	gliomas	glioma	NOUN
fnp-3804	21	22	in	in	ADP
fnp-3804	21	23	adults	adult	NOUN
fnp-3804	21	24	and	and	CCONJ
fnp-3804	21	25	for	for	ADP
fnp-3804	21	26	some	some	DET
fnp-3804	21	27	embryonal	embryonal	ADJ
fnp-3804	21	28	tumors	tumor	NOUN
fnp-3804	21	29	.	.	PUNCT
fnp-3804	22	1	in	in	ADP
fnp-3804	22	2	the	the	DET
fnp-3804	22	3	5th	5th	ADJ
fnp-3804	22	4	edition	edition	NOUN
fnp-3804	22	5	,	,	PUNCT
fnp-3804	22	6	molecular	molecular	ADJ
fnp-3804	22	7	features	feature	NOUN
fnp-3804	22	8	are	be	AUX
fnp-3804	22	9	introduced	introduce	VERB
fnp-3804	22	10	as	as	ADP
fnp-3804	22	11	essential	essential	ADJ
fnp-3804	22	12	diagnostic	diagnostic	ADJ
fnp-3804	22	13	criteria	criterion	NOUN
fnp-3804	22	14	for	for	ADP
fnp-3804	22	15	many	many	ADJ
fnp-3804	22	16	more	more	ADJ
fnp-3804	22	17	tumors	tumor	NOUN
fnp-3804	22	18	.	.	PUNCT
fnp-3804	23	1	in	in	ADP
fnp-3804	23	2	line	line	NOUN
fnp-3804	23	3	with	with	ADP
fnp-3804	23	4	recommendations	recommendation	NOUN
fnp-3804	23	5	of	of	ADP
fnp-3804	23	6	the	the	DET
fnp-3804	23	7	cimpact	cimpact	ADJ
fnp-3804	23	8	-	-	PUNCT
fnp-3804	23	9	now	now	ADV
fnp-3804	23	10	consortium	consortium	NOUN
fnp-3804	23	11	15	15	NUM
fnp-3804	23	12	,	,	PUNCT
fnp-3804	23	13	salient	salient	ADJ
fnp-3804	23	14	changes	change	NOUN
fnp-3804	23	15	in	in	ADP
fnp-3804	23	16	this	this	DET
fnp-3804	23	17	new	new	ADJ
fnp-3804	23	18	classification	classification	NOUN
fnp-3804	23	19	are	be	AUX
fnp-3804	23	20	the	the	DET
fnp-3804	23	21	separation	separation	NOUN
fnp-3804	23	22	of	of	ADP
fnp-3804	23	23	(	(	PUNCT
fnp-3804	23	24	groups	group	NOUN
fnp-3804	23	25	of	of	ADP
fnp-3804	23	26	)	)	PUNCT
fnp-3804	23	27	pediatric	pediatric	ADJ
fnp-3804	23	28	-	-	PUNCT
fnp-3804	23	29	type	type	NOUN
fnp-3804	23	30	low	low	ADJ
fnp-3804	23	31	-	-	PUNCT
fnp-3804	23	32	grade	grade	NOUN
fnp-3804	23	33	and	and	CCONJ
fnp-3804	23	34	pediatric	pediatric	ADJ
fnp-3804	23	35	-	-	PUNCT
fnp-3804	23	36	type	type	NOUN
fnp-3804	23	37	high	high	ADJ
fnp-3804	23	38	-	-	PUNCT
fnp-3804	23	39	grade	grade	NOUN
fnp-3804	23	40	diffuse	diffuse	NOUN
fnp-3804	23	41	gliomas	glioma	NOUN
fnp-3804	23	42	from	from	ADP
fnp-3804	23	43	adult	adult	NOUN
fnp-3804	23	44	-	-	PUNCT
fnp-3804	23	45	type	type	NOUN
fnp-3804	23	46	diffuse	diffuse	NOUN
fnp-3804	23	47	gliomas	glioma	NOUN
fnp-3804	23	48	,	,	PUNCT
fnp-3804	23	49	further	further	ADJ
fnp-3804	23	50	refinement	refinement	NOUN
fnp-3804	23	51	of	of	ADP
fnp-3804	23	52	the	the	DET
fnp-3804	23	53	classification	classification	NOUN
fnp-3804	23	54	of	of	ADP
fnp-3804	23	55	ependymal	ependymal	ADJ
fnp-3804	23	56	tumors	tumor	NOUN
fnp-3804	23	57	,	,	PUNCT
fnp-3804	23	58	and	and	CCONJ
fnp-3804	23	59	the	the	DET
fnp-3804	23	60	addition	addition	NOUN
fnp-3804	23	61	of	of	ADP
fnp-3804	23	62	a	a	DET
fnp-3804	23	63	few	few	ADJ
fnp-3804	23	64	newly	newly	ADV
fnp-3804	23	65	recognized	recognize	VERB
fnp-3804	23	66	tumors	tumor	NOUN
fnp-3804	23	67	in	in	ADP
fnp-3804	23	68	the	the	DET
fnp-3804	23	69	category	category	NOUN
fnp-3804	23	70	of	of	ADP
fnp-3804	23	71	cns	cns	PROPN
fnp-3804	23	72	embryonal	embryonal	ADJ
fnp-3804	23	73	tumors	tumor	NOUN
fnp-3804	23	74	.	.	PUNCT
fnp-3804	24	1	table	table	NOUN
fnp-3804	24	2	1	1	NUM
fnp-3804	24	3	provides	provide	VERB
fnp-3804	24	4	an	an	DET
fnp-3804	24	5	overview	overview	NOUN
fnp-3804	24	6	of	of	ADP
fnp-3804	24	7	these	these	DET
fnp-3804	24	8	changes	change	NOUN
fnp-3804	24	9	in	in	ADP
fnp-3804	24	10	the	the	PRON
fnp-3804	24	11	who	who	PRON
fnp-3804	24	12	cns5	cns5	VERB
fnp-3804	24	13	classification	classification	NOUN
fnp-3804	24	14	(	(	PUNCT
fnp-3804	24	15	with	with	ADP
fnp-3804	24	16	#	#	NOUN
fnp-3804	24	17	and	and	CCONJ
fnp-3804	24	18	*	*	PUNCT
fnp-3804	24	19	indicating	indicate	VERB
fnp-3804	24	20	the	the	DET
fnp-3804	24	21	newly	newly	ADV
fnp-3804	24	22	introduced	introduce	VERB
fnp-3804	24	23	and	and	CCONJ
fnp-3804	24	24	the	the	DET
fnp-3804	24	25	provisionally	provisionally	ADV
fnp-3804	24	26	accepted	accept	VERB
fnp-3804	24	27	tumor	tumor	NOUN
fnp-3804	24	28	types	type	NOUN
fnp-3804	24	29	,	,	PUNCT
fnp-3804	24	30	respectively	respectively	ADV
fnp-3804	24	31	)	)	PUNCT
fnp-3804	24	32	.	.	PUNCT
fnp-3804	25	1	another	another	DET
fnp-3804	25	2	important	important	ADJ
fnp-3804	25	3	change	change	NOUN
fnp-3804	25	4	is	be	AUX
fnp-3804	25	5	that	that	SCONJ
fnp-3804	25	6	grading	grade	VERB
fnp-3804	25	7	of	of	ADP
fnp-3804	25	8	neoplasms	neoplasm	NOUN
fnp-3804	25	9	is	be	AUX
fnp-3804	25	10	performed	perform	VERB
fnp-3804	25	11	in	in	ADP
fnp-3804	25	12	the	the	PRON
fnp-3804	25	13	who	who	PRON
fnp-3804	25	14	cns5	cns5	VERB
fnp-3804	25	15	classification	classification	NOUN
fnp-3804	25	16	within	within	ADP
fnp-3804	25	17	(	(	PUNCT
fnp-3804	25	18	rather	rather	ADV
fnp-3804	25	19	than	than	ADP
fnp-3804	25	20	across	across	ADP
fnp-3804	25	21	)	)	PUNCT
fnp-3804	25	22	tumor	tumor	NOUN
fnp-3804	25	23	types	type	NOUN
fnp-3804	25	24	,	,	PUNCT
fnp-3804	25	25	with	with	ADP
fnp-3804	25	26	arabic	arabic	ADJ
fnp-3804	25	27	(	(	PUNCT
fnp-3804	25	28	instead	instead	ADV
fnp-3804	25	29	of	of	ADP
fnp-3804	25	30	roman	roman	ADJ
fnp-3804	25	31	)	)	PUNCT
fnp-3804	25	32	numerals	numeral	NOUN
fnp-3804	25	33	now	now	ADV
fnp-3804	25	34	used	use	VERB
fnp-3804	25	35	for	for	ADP
fnp-3804	25	36	the	the	DET
fnp-3804	25	37	different	different	ADJ
fnp-3804	25	38	grades	grade	NOUN
fnp-3804	25	39	.	.	PUNCT
fnp-3804	26	1	thus	thus	ADV
fnp-3804	26	2	,	,	PUNCT
fnp-3804	26	3	in	in	ADP
fnp-3804	26	4	the	the	PRON
fnp-3804	26	5	who	who	PRON
fnp-3804	26	6	cns5	cns5	PROPN
fnp-3804	26	7	classification	classification	NOUN
fnp-3804	26	8	there	there	PRON
fnp-3804	26	9	is	be	VERB
fnp-3804	26	10	only	only	ADV
fnp-3804	26	11	one	one	NUM
fnp-3804	26	12	entry	entry	NOUN
fnp-3804	26	13	for	for	ADP
fnp-3804	26	14	e.g.	e.g.	ADJ
fnp-3804	26	15	astrocytoma	astrocytoma	NOUN
fnp-3804	26	16	,	,	PUNCT
fnp-3804	26	17	idh	idh	NOUN
fnp-3804	26	18	-	-	PUNCT
fnp-3804	26	19	mutant	mutant	NOUN
fnp-3804	26	20	,	,	PUNCT
fnp-3804	26	21	and	and	CCONJ
fnp-3804	26	22	one	one	NUM
fnp-3804	26	23	for	for	ADP
fnp-3804	26	24	meningioma	meningioma	NOUN
fnp-3804	26	25	(	(	PUNCT
fnp-3804	26	26	rather	rather	ADV
fnp-3804	26	27	than	than	ADP
fnp-3804	26	28	separate	separate	ADJ
fnp-3804	26	29	entries	entry	NOUN
fnp-3804	26	30	for	for	ADP
fnp-3804	26	31	e.g.	e.g.	ADJ
fnp-3804	26	32	anaplastic	anaplastic	ADJ
fnp-3804	26	33	astrocytoma	astrocytoma	NOUN
fnp-3804	26	34	,	,	PUNCT
fnp-3804	26	35	idh	idh	NOUN
fnp-3804	26	36	-	-	PUNCT
fnp-3804	26	37	mutant	mutant	NOUN
fnp-3804	26	38	,	,	PUNCT
fnp-3804	26	39	or	or	CCONJ
fnp-3804	26	40	for	for	ADP
fnp-3804	26	41	atypical	atypical	ADJ
fnp-3804	26	42	meningioma	meningioma	NOUN
fnp-3804	26	43	)	)	PUNCT
fnp-3804	26	44	.	.	PUNCT
fnp-3804	27	1	also	also	ADV
fnp-3804	27	2	,	,	PUNCT
fnp-3804	27	3	glioblastoma	glioblastoma	NOUN
fnp-3804	27	4	,	,	PUNCT
fnp-3804	27	5	idh	idh	NOUN
fnp-3804	27	6	-	-	PUNCT
fnp-3804	27	7	mutant	mutant	NOUN
fnp-3804	27	8	should	should	AUX
fnp-3804	27	9	now	now	ADV
fnp-3804	27	10	be	be	AUX
fnp-3804	27	11	diagnosed	diagnose	VERB
fnp-3804	27	12	as	as	ADP
fnp-3804	27	13	astrocytoma	astrocytoma	NOUN
fnp-3804	27	14	,	,	PUNCT
fnp-3804	27	15	idh	idh	NOUN
fnp-3804	27	16	-	-	PUNCT
fnp-3804	27	17	mutant	mutant	NOUN
fnp-3804	27	18	,	,	PUNCT
fnp-3804	27	19	cns	cns	PROPN
fnp-3804	27	20	who	who	PRON
fnp-3804	27	21	grade	grade	VERB
fnp-3804	27	22	4	4	NUM
fnp-3804	27	23	.	.	PUNCT
fnp-3804	27	24	table	table	NOUN
fnp-3804	27	25	1	1	NUM
fnp-3804	27	26	.	.	PUNCT
fnp-3804	27	27	who	who	PRON
fnp-3804	27	28	classification	classification	VERB
fnp-3804	27	29	of	of	ADP
fnp-3804	27	30	primary	primary	ADJ
fnp-3804	27	31	cns	cns	NOUN
fnp-3804	27	32	tumors	tumor	NOUN
fnp-3804	27	33	,	,	PUNCT
fnp-3804	27	34	5th	5th	ADJ
fnp-3804	27	35	edition	edition	NOUN
fnp-3804	27	36	(	(	PUNCT
fnp-3804	27	37	2021).major	2021).major	NOUN
fnp-3804	27	38	changes	change	NOUN
fnp-3804	27	39	in	in	ADP
fnp-3804	27	40	the	the	PRON
fnp-3804	27	41	who	who	PRON
fnp-3804	27	42	cns5	cns5	PROPN
fnp-3804	27	43	classification	classification	NOUN
fnp-3804	27	44	are	be	AUX
fnp-3804	27	45	the	the	DET
fnp-3804	27	46	separation	separation	NOUN
fnp-3804	27	47	of	of	ADP
fnp-3804	27	48	(	(	PUNCT
fnp-3804	27	49	low	low	ADJ
fnp-3804	27	50	-	-	PUNCT
fnp-3804	27	51	grade	grade	NOUN
fnp-3804	27	52	and	and	CCONJ
fnp-3804	27	53	high	high	ADJ
fnp-3804	27	54	-	-	PUNCT
fnp-3804	27	55	grade	grade	NOUN
fnp-3804	27	56	)	)	PUNCT
fnp-3804	27	57	pediatric	pediatric	ADJ
fnp-3804	27	58	-	-	PUNCT
fnp-3804	27	59	type	type	NOUN
fnp-3804	27	60	diffuse	diffuse	NOUN
fnp-3804	27	61	gliomas	glioma	NOUN
fnp-3804	27	62	from	from	ADP
fnp-3804	27	63	adult	adult	NOUN
fnp-3804	27	64	-	-	PUNCT
fnp-3804	27	65	type	type	NOUN
fnp-3804	27	66	diffuse	diffuse	NOUN
fnp-3804	27	67	gliomas	glioma	NOUN
fnp-3804	27	68	;	;	PUNCT
fnp-3804	27	69	the	the	DET
fnp-3804	27	70	recognition	recognition	NOUN
fnp-3804	27	71	of	of	ADP
fnp-3804	27	72	several	several	ADJ
fnp-3804	27	73	new	new	ADJ
fnp-3804	27	74	ependymal	ependymal	ADJ
fnp-3804	27	75	,	,	PUNCT
fnp-3804	27	76	embryonal	embryonal	ADJ
fnp-3804	27	77	and	and	CCONJ
fnp-3804	27	78	other	other	ADJ
fnp-3804	27	79	tumor	tumor	NOUN
fnp-3804	27	80	types	type	NOUN
fnp-3804	27	81	;	;	PUNCT
fnp-3804	27	82	assigning	assign	VERB
fnp-3804	27	83	of	of	ADP
fnp-3804	27	84	cns	cns	PROPN
fnp-3804	27	85	who	who	PRON
fnp-3804	27	86	grades	grade	VERB
fnp-3804	27	87	within	within	ADP
fnp-3804	27	88	tumor	tumor	NOUN
fnp-3804	27	89	types	type	NOUN
fnp-3804	27	90	;	;	PUNCT
fnp-3804	27	91	coining	coin	VERB
fnp-3804	27	92	the	the	DET
fnp-3804	27	93	most	most	ADV
fnp-3804	27	94	malignant	malignant	ADJ
fnp-3804	27	95	idh	idh	NOUN
fnp-3804	27	96	-	-	PUNCT
fnp-3804	27	97	mutant	mutant	NOUN
fnp-3804	27	98	diffuse	diffuse	NOUN
fnp-3804	27	99	astrocytic	astrocytic	ADJ
fnp-3804	27	100	tumor	tumor	NOUN
fnp-3804	27	101	as	as	ADP
fnp-3804	27	102	astrocytoma	astrocytoma	NOUN
fnp-3804	27	103	,	,	PUNCT
fnp-3804	27	104	idh	idh	NOUN
fnp-3804	27	105	-	-	PUNCT
fnp-3804	27	106	mutant	mutant	NOUN
fnp-3804	27	107	,	,	PUNCT
fnp-3804	27	108	cns	cns	PROPN
fnp-3804	27	109	who	who	PRON
fnp-3804	27	110	grade	grade	VERB
fnp-3804	27	111	4	4	NUM
fnp-3804	27	112	;	;	PUNCT
fnp-3804	27	113	and	and	CCONJ
fnp-3804	27	114	changing	change	VERB
fnp-3804	27	115	the	the	DET
fnp-3804	27	116	name	name	NOUN
fnp-3804	27	117	of	of	ADP
fnp-3804	27	118	diffuse	diffuse	ADJ
fnp-3804	27	119	midline	midline	NOUN
fnp-3804	27	120	glioma	glioma	NOUN
fnp-3804	27	121	(	(	PUNCT
fnp-3804	27	122	dmg	dmg	NOUN
fnp-3804	27	123	)	)	PUNCT
fnp-3804	27	124	,	,	PUNCT
fnp-3804	27	125	h3	h3	VERB
fnp-3804	27	126	k27m	k27m	NOUN
fnp-3804	27	127	-	-	NOUN
fnp-3804	27	128	mutant	mutant	NOUN
fnp-3804	27	129	into	into	ADP
fnp-3804	27	130	dmg	dmg	PROPN
fnp-3804	27	131	,	,	PUNCT
fnp-3804	27	132	h3k27	h3k27	NOUN
fnp-3804	27	133	-	-	PUNCT
fnp-3804	27	134	altered	altered	ADJ
fnp-3804	27	135	.	.	PUNCT
fnp-3804	28	1	see	see	VERB
fnp-3804	28	2	summary	summary	NOUN
fnp-3804	28	3	of	of	ADP
fnp-3804	28	4	louis	louis	PROPN
fnp-3804	28	5	dn	dn	PROPN
fnp-3804	28	6	et	et	PROPN
fnp-3804	28	7	al	al	PROPN
fnp-3804	28	8	.	.	PROPN
fnp-3804	28	9	1	1	NUM
fnp-3804	28	10	or	or	CCONJ
fnp-3804	28	11	,	,	PUNCT
fnp-3804	28	12	even	even	ADV
fnp-3804	28	13	better	well	ADJ
fnp-3804	28	14	,	,	PUNCT
fnp-3804	28	15	the	the	DET
fnp-3804	28	16	(	(	PUNCT
fnp-3804	28	17	digital	digital	ADJ
fnp-3804	28	18	version	version	NOUN
fnp-3804	28	19	of	of	ADP
fnp-3804	28	20	the	the	PRON
fnp-3804	28	21	)	)	PUNCT
fnp-3804	28	22	‘	'	PUNCT
fnp-3804	28	23	blue	blue	ADJ
fnp-3804	28	24	book	book	NOUN
fnp-3804	28	25	’	'	PUNCT
fnp-3804	28	26	for	for	ADP
fnp-3804	28	27	much	much	ADV
fnp-3804	28	28	more	more	ADJ
fnp-3804	28	29	information	information	NOUN
fnp-3804	28	30	of	of	ADP
fnp-3804	28	31	these	these	DET
fnp-3804	28	32	changes	change	NOUN
fnp-3804	28	33	.	.	PUNCT
fnp-3804	29	1	in	in	ADP
fnp-3804	29	2	red	red	PROPN
fnp-3804	29	3	&	&	CCONJ
fnp-3804	29	4	capitals	capital	NOUN
fnp-3804	29	5	&	&	CCONJ
fnp-3804	29	6	italics	italic	NOUN
fnp-3804	29	7	:	:	PUNCT
fnp-3804	29	8	overarching	overarching	ADJ
fnp-3804	29	9	categories	category	NOUN
fnp-3804	29	10	of	of	ADP
fnp-3804	29	11	tumors	tumor	NOUN
fnp-3804	29	12	;	;	PUNCT
fnp-3804	29	13	in	in	ADP
fnp-3804	29	14	bold	bold	ADJ
fnp-3804	29	15	and	and	CCONJ
fnp-3804	29	16	italics	italic	NOUN
fnp-3804	29	17	:	:	PUNCT
fnp-3804	29	18	groups	group	NOUN
fnp-3804	29	19	of	of	ADP
fnp-3804	29	20	tumor	tumor	NOUN
fnp-3804	29	21	types	type	NOUN
fnp-3804	29	22	,	,	PUNCT
fnp-3804	29	23	and	and	CCONJ
fnp-3804	29	24	under	under	ADP
fnp-3804	29	25	these	these	DET
fnp-3804	29	26	groups	group	NOUN
fnp-3804	29	27	(	(	PUNCT
fnp-3804	29	28	with	with	ADP
fnp-3804	29	29	a	a	DET
fnp-3804	29	30	few	few	ADJ
fnp-3804	29	31	exceptions	exception	NOUN
fnp-3804	29	32	)	)	PUNCT
fnp-3804	29	33	the	the	DET
fnp-3804	29	34	individual	individual	ADJ
fnp-3804	29	35	tumor	tumor	NOUN
fnp-3804	29	36	types	type	NOUN
fnp-3804	29	37	;	;	PUNCT
fnp-3804	29	38	#	#	NOUN
fnp-3804	29	39	=	=	SYM
fnp-3804	29	40	newly	newly	ADV
fnp-3804	29	41	defined	define	VERB
fnp-3804	29	42	tumor	tumor	NOUN
fnp-3804	29	43	type	type	NOUN
fnp-3804	29	44	compared	compare	VERB
fnp-3804	29	45	to	to	ADP
fnp-3804	29	46	the	the	DET
fnp-3804	29	47	2016	2016	NUM
fnp-3804	29	48	edition	edition	NOUN
fnp-3804	29	49	;	;	PUNCT
fnp-3804	29	50	*	*	PUNCT
fnp-3804	29	51	=	=	SYM
fnp-3804	29	52	provisional	provisional	ADJ
fnp-3804	29	53	tumor	tumor	NOUN
fnp-3804	29	54	type	type	NOUN
fnp-3804	29	55	;	;	PUNCT
fnp-3804	29	56	@	@	NUM
fnp-3804	29	57	=	=	PUNCT
fnp-3804	29	58	tumor	tumor	NOUN
fnp-3804	29	59	with	with	ADP
fnp-3804	29	60	revised	revise	VERB
fnp-3804	29	61	nomenclature	nomenclature	NOUN
fnp-3804	29	62	or	or	CCONJ
fnp-3804	29	63	revised	revise	VERB
fnp-3804	29	64	placement	placement	NOUN
fnp-3804	29	65	.	.	PUNCT
fnp-3804	30	1	click	click	VERB
fnp-3804	30	2	here	here	ADV
fnp-3804	30	3	to	to	PART
fnp-3804	30	4	view	view	VERB
fnp-3804	30	5	a	a	DET
fnp-3804	30	6	large	large	ADJ
fnp-3804	30	7	version	version	NOUN
fnp-3804	30	8	of	of	ADP
fnp-3804	30	9	this	this	DET
fnp-3804	30	10	table	table	NOUN
fnp-3804	30	11	.	.	PUNCT
fnp-3804	31	1	furthermore	furthermore	ADV
fnp-3804	31	2	,	,	PUNCT
fnp-3804	31	3	the	the	DET
fnp-3804	31	4	presence	presence	NOUN
fnp-3804	31	5	of	of	ADP
fnp-3804	31	6	tert	tert	NOUN
fnp-3804	31	7	promoter	promoter	NOUN
fnp-3804	31	8	mutation	mutation	NOUN
fnp-3804	31	9	,	,	PUNCT
fnp-3804	31	10	egfr	egfr	ADJ
fnp-3804	31	11	amplification	amplification	NOUN
fnp-3804	31	12	and/or	and/or	CCONJ
fnp-3804	31	13	the	the	DET
fnp-3804	31	14	combination	combination	NOUN
fnp-3804	31	15	of	of	ADP
fnp-3804	31	16	gain	gain	NOUN
fnp-3804	31	17	of	of	ADP
fnp-3804	31	18	complete	complete	ADJ
fnp-3804	31	19	chromosome	chromosome	NOUN
fnp-3804	31	20	7	7	NUM
fnp-3804	31	21	and	and	CCONJ
fnp-3804	31	22	loss	loss	NOUN
fnp-3804	31	23	of	of	ADP
fnp-3804	31	24	complete	complete	ADJ
fnp-3804	31	25	chromosome	chromosome	NOUN
fnp-3804	31	26	10	10	NUM
fnp-3804	31	27	can	can	AUX
fnp-3804	31	28	now	now	ADV
fnp-3804	31	29	be	be	AUX
fnp-3804	31	30	used	use	VERB
fnp-3804	31	31	for	for	ADP
fnp-3804	31	32	diagnosing	diagnose	VERB
fnp-3804	31	33	an	an	DET
fnp-3804	31	34	adult	adult	NOUN
fnp-3804	31	35	-	-	PUNCT
fnp-3804	31	36	type	type	NOUN
fnp-3804	31	37	,	,	PUNCT
fnp-3804	31	38	histologically	histologically	ADV
fnp-3804	31	39	lower	low	ADJ
fnp-3804	31	40	grade	grade	NOUN
fnp-3804	31	41	,	,	PUNCT
fnp-3804	31	42	idh	idh	NOUN
fnp-3804	31	43	-	-	PUNCT
fnp-3804	31	44	wildtype	wildtype	NOUN
fnp-3804	31	45	diffuse	diffuse	NOUN
fnp-3804	31	46	glioma	glioma	NOUN
fnp-3804	31	47	as	as	ADP
fnp-3804	31	48	glioblastoma	glioblastoma	NOUN
fnp-3804	31	49	,	,	PUNCT
fnp-3804	31	50	idh	idh	NOUN
fnp-3804	31	51	-	-	PUNCT
fnp-3804	31	52	wildtype	wildtype	NOUN
fnp-3804	31	53	(	(	PUNCT
fnp-3804	31	54	cns	cns	X
fnp-3804	31	55	who	who	PRON
fnp-3804	31	56	grade	grade	VERB
fnp-3804	31	57	4	4	NUM
fnp-3804	31	58	)	)	PUNCT
fnp-3804	31	59	,	,	PUNCT
fnp-3804	31	60	and	and	CCONJ
fnp-3804	31	61	the	the	DET
fnp-3804	31	62	presence	presence	NOUN
fnp-3804	31	63	of	of	ADP
fnp-3804	31	64	homozygous	homozygous	ADJ
fnp-3804	31	65	cdkn2a	cdkn2a	PROPN
fnp-3804	31	66	/	/	SYM
fnp-3804	31	67	b	b	NOUN
fnp-3804	31	68	loss	loss	NOUN
fnp-3804	31	69	to	to	PART
fnp-3804	31	70	diagnose	diagnose	VERB
fnp-3804	31	71	a	a	DET
fnp-3804	31	72	histologically	histologically	ADV
fnp-3804	31	73	lower	low	ADJ
fnp-3804	31	74	grade	grade	NOUN
fnp-3804	31	75	,	,	PUNCT
fnp-3804	31	76	idh	idh	NOUN
fnp-3804	31	77	-	-	PUNCT
fnp-3804	31	78	mutant	mutant	NOUN
fnp-3804	31	79	diffuse	diffuse	NOUN
fnp-3804	31	80	astrocytoma	astrocytoma	NOUN
fnp-3804	31	81	as	as	ADP
fnp-3804	31	82	cns	cns	PROPN
fnp-3804	31	83	who	who	PRON
fnp-3804	31	84	grade	grade	VERB
fnp-3804	31	85	4	4	NUM
fnp-3804	31	86	.	.	PUNCT
fnp-3804	31	87	for	for	ADP
fnp-3804	31	88	yet	yet	CCONJ
fnp-3804	31	89	other	other	ADJ
fnp-3804	31	90	tumors	tumor	NOUN
fnp-3804	31	91	the	the	DET
fnp-3804	31	92	name	name	NOUN
fnp-3804	31	93	or	or	CCONJ
fnp-3804	31	94	their	their	PRON
fnp-3804	31	95	placement	placement	NOUN
fnp-3804	31	96	in	in	ADP
fnp-3804	31	97	the	the	DET
fnp-3804	31	98	classification	classification	NOUN
fnp-3804	31	99	was	be	AUX
fnp-3804	31	100	changed	change	VERB
fnp-3804	31	101	as	as	ADV
fnp-3804	31	102	well	well	ADV
fnp-3804	31	103	(	(	PUNCT
fnp-3804	31	104	@	@	ADP
fnp-3804	31	105	in	in	ADP
fnp-3804	31	106	table	table	NOUN
fnp-3804	31	107	1	1	NUM
fnp-3804	31	108	)	)	PUNCT
fnp-3804	31	109	.	.	PUNCT
fnp-3804	32	1	for	for	ADP
fnp-3804	32	2	example	example	NOUN
fnp-3804	32	3	,	,	PUNCT
fnp-3804	32	4	h3k27m	h3k27m	NOUN
fnp-3804	32	5	-	-	NOUN
fnp-3804	32	6	mutant	mutant	NOUN
fnp-3804	32	7	after	after	ADP
fnp-3804	32	8	diffuse	diffuse	NOUN
fnp-3804	32	9	midline	midline	NOUN
fnp-3804	32	10	glioma	glioma	NOUN
fnp-3804	32	11	(	(	PUNCT
fnp-3804	32	12	dmg	dmg	NOUN
fnp-3804	32	13	)	)	PUNCT
fnp-3804	32	14	was	be	AUX
fnp-3804	32	15	changed	change	VERB
fnp-3804	32	16	into	into	ADP
fnp-3804	32	17	h3k27	h3k27	NOUN
fnp-3804	32	18	-	-	ADJ
fnp-3804	32	19	altered	altered	ADJ
fnp-3804	32	20	because	because	SCONJ
fnp-3804	32	21	there	there	PRON
fnp-3804	32	22	are	be	VERB
fnp-3804	32	23	h3	h3	NOUN
fnp-3804	32	24	-	-	PUNCT
fnp-3804	32	25	wildtype	wildtype	NOUN
fnp-3804	32	26	dmgs	dmgs	NOUN
fnp-3804	32	27	especially	especially	ADV
fnp-3804	32	28	in	in	ADP
fnp-3804	32	29	children	child	NOUN
fnp-3804	32	30	that	that	PRON
fnp-3804	32	31	do	do	AUX
fnp-3804	32	32	show	show	VERB
fnp-3804	32	33	loss	loss	NOUN
fnp-3804	32	34	of	of	ADP
fnp-3804	32	35	nuclear	nuclear	ADJ
fnp-3804	32	36	h3k27me3	h3k27me3	NOUN
fnp-3804	32	37	staining	stain	VERB
fnp-3804	32	38	and	and	CCONJ
fnp-3804	32	39	with	with	ADP
fnp-3804	32	40	a	a	DET
fnp-3804	32	41	similar	similar	ADJ
fnp-3804	32	42	prognosis	prognosis	NOUN
fnp-3804	32	43	as	as	ADP
fnp-3804	32	44	dmgs	dmgs	NOUN
fnp-3804	32	45	,	,	PUNCT
fnp-3804	32	46	h3k27m	h3k27m	NOUN
fnp-3804	32	47	-	-	NOUN
fnp-3804	32	48	mutant	mutant	NOUN
fnp-3804	32	49	.	.	PUNCT
fnp-3804	33	1	also	also	ADV
fnp-3804	33	2	,	,	PUNCT
fnp-3804	33	3	the	the	DET
fnp-3804	33	4	name	name	NOUN
fnp-3804	33	5	rela	rela	NOUN
fnp-3804	33	6	fusion	fusion	NOUN
fnp-3804	33	7	-	-	PUNCT
fnp-3804	33	8	positive	positive	ADJ
fnp-3804	33	9	for	for	ADP
fnp-3804	33	10	a	a	DET
fnp-3804	33	11	subset	subset	NOUN
fnp-3804	33	12	of	of	ADP
fnp-3804	33	13	supratentorial	supratentorial	ADJ
fnp-3804	33	14	ependymoma	ependymoma	NOUN
fnp-3804	33	15	was	be	AUX
fnp-3804	33	16	changed	change	VERB
fnp-3804	33	17	into	into	ADP
fnp-3804	33	18	zfta	zfta	NOUN
fnp-3804	33	19	fusion	fusion	NOUN
fnp-3804	33	20	-	-	PUNCT
fnp-3804	33	21	positive	positive	ADJ
fnp-3804	33	22	,	,	PUNCT
fnp-3804	33	23	as	as	SCONJ
fnp-3804	33	24	zfta	zfta	PROPN
fnp-3804	33	25	(	(	PUNCT
fnp-3804	33	26	‘	'	PUNCT
fnp-3804	33	27	zinc	zinc	NOUN
fnp-3804	33	28	finger	finger	NOUN
fnp-3804	33	29	translocation	translocation	NOUN
fnp-3804	33	30	associated	associate	VERB
fnp-3804	33	31	’	'	PUNCT
fnp-3804	33	32	,	,	PUNCT
fnp-3804	33	33	the	the	DET
fnp-3804	33	34	new	new	ADJ
fnp-3804	33	35	name	name	NOUN
fnp-3804	33	36	for	for	ADP
fnp-3804	33	37	c11orf95	c11orf95	NOUN
fnp-3804	33	38	)	)	PUNCT
fnp-3804	33	39	appears	appear	VERB
fnp-3804	33	40	to	to	PART
fnp-3804	33	41	be	be	AUX
fnp-3804	33	42	the	the	DET
fnp-3804	33	43	more	more	ADV
fnp-3804	33	44	frequent	frequent	ADJ
fnp-3804	33	45	fusion	fusion	NOUN
fnp-3804	33	46	partner	partner	NOUN
fnp-3804	33	47	in	in	ADP
fnp-3804	33	48	these	these	DET
fnp-3804	33	49	tumors	tumor	NOUN
fnp-3804	33	50	(	(	PUNCT
fnp-3804	33	51	most	most	ADV
fnp-3804	33	52	frequently	frequently	ADV
fnp-3804	33	53	showing	show	VERB
fnp-3804	33	54	fusion	fusion	NOUN
fnp-3804	33	55	with	with	ADP
fnp-3804	33	56	rela	rela	PROPN
fnp-3804	33	57	)	)	PUNCT
fnp-3804	33	58	.	.	PUNCT
fnp-3804	34	1	compared	compare	VERB
fnp-3804	34	2	to	to	ADP
fnp-3804	34	3	the	the	DET
fnp-3804	34	4	revised	revise	VERB
fnp-3804	34	5	fourth	fourth	PROPN
fnp-3804	34	6	edition	edition	NOUN
fnp-3804	34	7	,	,	PUNCT
fnp-3804	34	8	the	the	PRON
fnp-3804	34	9	who	who	PRON
fnp-3804	34	10	cns5	cns5	VERB
fnp-3804	34	11	tumor	tumor	NOUN
fnp-3804	34	12	classification	classification	NOUN
fnp-3804	34	13	certainly	certainly	ADV
fnp-3804	34	14	is	be	AUX
fnp-3804	34	15	an	an	DET
fnp-3804	34	16	improvement	improvement	NOUN
fnp-3804	34	17	.	.	PUNCT
fnp-3804	35	1	however	however	ADV
fnp-3804	35	2	,	,	PUNCT
fnp-3804	35	3	as	as	SCONJ
fnp-3804	35	4	discussed	discuss	VERB
fnp-3804	35	5	in	in	ADP
fnp-3804	35	6	somewhat	somewhat	ADV
fnp-3804	35	7	more	more	ADJ
fnp-3804	35	8	detail	detail	NOUN
fnp-3804	35	9	in	in	ADP
fnp-3804	35	10	the	the	DET
fnp-3804	35	11	last	last	ADJ
fnp-3804	35	12	part	part	NOUN
fnp-3804	35	13	of	of	ADP
fnp-3804	35	14	this	this	DET
fnp-3804	35	15	review	review	NOUN
fnp-3804	35	16	,	,	PUNCT
fnp-3804	35	17	this	this	DET
fnp-3804	35	18	new	new	ADJ
fnp-3804	35	19	classification	classification	NOUN
fnp-3804	35	20	brings	bring	VERB
fnp-3804	35	21	several	several	ADJ
fnp-3804	35	22	challenges	challenge	NOUN
fnp-3804	35	23	as	as	ADV
fnp-3804	35	24	well	well	ADV
fnp-3804	35	25	,	,	PUNCT
fnp-3804	35	26	e.g.	e.g.	ADV
fnp-3804	35	27	,	,	PUNCT
fnp-3804	35	28	related	relate	VERB
fnp-3804	35	29	to	to	ADP
fnp-3804	35	30	the	the	DET
fnp-3804	35	31	(	(	PUNCT
fnp-3804	35	32	lack	lack	NOUN
fnp-3804	35	33	of	of	ADP
fnp-3804	35	34	)	)	PUNCT
fnp-3804	35	35	availability	availability	NOUN
fnp-3804	35	36	of	of	ADP
fnp-3804	35	37	molecular	molecular	ADJ
fnp-3804	35	38	diagnostic	diagnostic	ADJ
fnp-3804	35	39	tools	tool	NOUN
fnp-3804	35	40	,	,	PUNCT
fnp-3804	35	41	finding	find	VERB
fnp-3804	35	42	the	the	DET
fnp-3804	35	43	optimal	optimal	ADJ
fnp-3804	35	44	therapeutic	therapeutic	ADJ
fnp-3804	35	45	management	management	NOUN
fnp-3804	35	46	for	for	ADP
fnp-3804	35	47	newly	newly	ADV
fnp-3804	35	48	defined	define	VERB
fnp-3804	35	49	tumor	tumor	NOUN
fnp-3804	35	50	types	type	NOUN
fnp-3804	35	51	,	,	PUNCT
fnp-3804	35	52	and	and	CCONJ
fnp-3804	35	53	the	the	DET
fnp-3804	35	54	fact	fact	NOUN
fnp-3804	35	55	that	that	SCONJ
fnp-3804	35	56	a	a	DET
fnp-3804	35	57	more	more	ADV
fnp-3804	35	58	refined	refined	ADJ
fnp-3804	35	59	taxonomy	taxonomy	NOUN
fnp-3804	35	60	of	of	ADP
fnp-3804	35	61	cns	cns	PROPN
fnp-3804	35	62	tumors	tumor	NOUN
fnp-3804	35	63	makes	make	VERB
fnp-3804	35	64	it	it	PRON
fnp-3804	35	65	more	more	ADV
fnp-3804	35	66	difficult	difficult	ADJ
fnp-3804	35	67	to	to	PART
fnp-3804	35	68	perform	perform	VERB
fnp-3804	35	69	studies	study	NOUN
fnp-3804	35	70	on	on	ADP
fnp-3804	35	71	a	a	DET
fnp-3804	35	72	large	large	ADJ
fnp-3804	35	73	number	number	NOUN
fnp-3804	35	74	of	of	ADP
fnp-3804	35	75	patients	patient	NOUN
fnp-3804	35	76	.	.	PUNCT
fnp-3804	36	1	topic	topic	NOUN
fnp-3804	36	2	2	2	NUM
fnp-3804	36	3	:	:	PUNCT
fnp-3804	36	4	glioma	glioma	NOUN
fnp-3804	36	5	driver	driver	NOUN
fnp-3804	36	6	mutations	mutation	NOUN
fnp-3804	36	7	in	in	ADP
fnp-3804	36	8	the	the	DET
fnp-3804	36	9	normal	normal	ADJ
fnp-3804	36	10	human	human	ADJ
fnp-3804	36	11	brain	brain	NOUN
fnp-3804	36	12	2	2	NUM
fnp-3804	36	13	cancer	cancer	NOUN
fnp-3804	36	14	is	be	AUX
fnp-3804	36	15	a	a	DET
fnp-3804	36	16	disease	disease	NOUN
fnp-3804	36	17	characterized	characterize	VERB
fnp-3804	36	18	by	by	ADP
fnp-3804	36	19	the	the	DET
fnp-3804	36	20	accumulation	accumulation	NOUN
fnp-3804	36	21	of	of	ADP
fnp-3804	36	22	genomic	genomic	ADJ
fnp-3804	36	23	aberrations	aberration	NOUN
fnp-3804	36	24	that	that	PRON
fnp-3804	36	25	confer	confer	VERB
fnp-3804	36	26	a	a	DET
fnp-3804	36	27	proliferative	proliferative	ADJ
fnp-3804	36	28	advantage	advantage	NOUN
fnp-3804	36	29	.	.	PUNCT
fnp-3804	37	1	also	also	ADV
fnp-3804	37	2	,	,	PUNCT
fnp-3804	37	3	somatic	somatic	ADJ
fnp-3804	37	4	mutations	mutation	NOUN
fnp-3804	37	5	and	and	CCONJ
fnp-3804	37	6	copy	copy	VERB
fnp-3804	37	7	number	number	NOUN
fnp-3804	37	8	variations	variation	NOUN
fnp-3804	37	9	have	have	AUX
fnp-3804	37	10	been	be	AUX
fnp-3804	37	11	described	describe	VERB
fnp-3804	37	12	to	to	PART
fnp-3804	37	13	accrue	accrue	VERB
fnp-3804	37	14	with	with	ADP
fnp-3804	37	15	age	age	NOUN
fnp-3804	37	16	in	in	ADP
fnp-3804	37	17	(	(	PUNCT
fnp-3804	37	18	seemingly	seemingly	ADV
fnp-3804	37	19	)	)	PUNCT
fnp-3804	37	20	normal	normal	ADJ
fnp-3804	37	21	tissues	tissue	NOUN
fnp-3804	37	22	16	16	NUM
fnp-3804	37	23	.	.	PUNCT
fnp-3804	38	1	however	however	ADV
fnp-3804	38	2	,	,	PUNCT
fnp-3804	38	3	relatively	relatively	ADV
fnp-3804	38	4	little	little	ADJ
fnp-3804	38	5	is	be	AUX
fnp-3804	38	6	known	know	VERB
fnp-3804	38	7	about	about	ADP
fnp-3804	38	8	this	this	DET
fnp-3804	38	9	phenomenon	phenomenon	NOUN
fnp-3804	38	10	in	in	ADP
fnp-3804	38	11	the	the	DET
fnp-3804	38	12	normal	normal	ADJ
fnp-3804	38	13	brain	brain	NOUN
fnp-3804	38	14	.	.	PUNCT
fnp-3804	39	1	ganz	ganz	PROPN
fnp-3804	39	2	j	j	PROPN
fnp-3804	39	3	and	and	CCONJ
fnp-3804	39	4	maury	maury	PROPN
fnp-3804	39	5	ea	ea	PROPN
fnp-3804	39	6	et	et	PROPN
fnp-3804	39	7	al	al	PROPN
fnp-3804	39	8	.	.	PUNCT
fnp-3804	40	1	(	(	PUNCT
fnp-3804	40	2	with	with	ADP
fnp-3804	40	3	lee	lee	PROPN
fnp-3804	40	4	ea	ea	PROPN
fnp-3804	40	5	and	and	CCONJ
fnp-3804	40	6	walsh	walsh	PROPN
fnp-3804	40	7	ca	can	AUX
fnp-3804	40	8	as	as	SCONJ
fnp-3804	40	9	corresponding	corresponding	ADJ
fnp-3804	40	10	authors	author	NOUN
fnp-3804	40	11	)	)	PUNCT
fnp-3804	40	12	published	publish	VERB
fnp-3804	40	13	a	a	DET
fnp-3804	40	14	paper	paper	NOUN
fnp-3804	40	15	in	in	ADP
fnp-3804	40	16	cancer	cancer	NOUN
fnp-3804	40	17	discovery	discovery	NOUN
fnp-3804	40	18	2	2	NUM
fnp-3804	40	19	in	in	ADP
fnp-3804	40	20	which	which	PRON
fnp-3804	40	21	they	they	PRON
fnp-3804	40	22	used	use	VERB
fnp-3804	40	23	targeted	target	VERB
fnp-3804	40	24	gene	gene	NOUN
fnp-3804	40	25	sequencing	sequence	VERB
fnp-3804	40	26	on	on	ADP
fnp-3804	40	27	cerebral	cerebral	ADJ
fnp-3804	40	28	gray	gray	ADJ
fnp-3804	40	29	and	and	CCONJ
fnp-3804	40	30	white	white	ADJ
fnp-3804	40	31	matter	matter	NOUN
fnp-3804	40	32	samples	sample	NOUN
fnp-3804	40	33	of	of	ADP
fnp-3804	40	34	110	110	NUM
fnp-3804	40	35	individuals	individual	NOUN
fnp-3804	40	36	to	to	PART
fnp-3804	40	37	investigate	investigate	VERB
fnp-3804	40	38	the	the	DET
fnp-3804	40	39	presence	presence	NOUN
fnp-3804	40	40	of	of	ADP
fnp-3804	40	41	oncogenic	oncogenic	ADJ
fnp-3804	40	42	variants	variant	NOUN
fnp-3804	40	43	in	in	ADP
fnp-3804	40	44	normal	normal	ADJ
fnp-3804	40	45	brain	brain	NOUN
fnp-3804	40	46	tissue	tissue	NOUN
fnp-3804	40	47	.	.	PUNCT
fnp-3804	41	1	the	the	DET
fnp-3804	41	2	121	121	NUM
fnp-3804	41	3	-	-	PUNCT
fnp-3804	41	4	gene	gene	NOUN
fnp-3804	41	5	panel	panel	NOUN
fnp-3804	41	6	was	be	AUX
fnp-3804	41	7	selected	select	VERB
fnp-3804	41	8	for	for	ADP
fnp-3804	41	9	genes	gene	NOUN
fnp-3804	41	10	implicated	implicate	VERB
fnp-3804	41	11	in	in	ADP
fnp-3804	41	12	different	different	ADJ
fnp-3804	41	13	diseases	disease	NOUN
fnp-3804	41	14	and	and	CCONJ
fnp-3804	41	15	previously	previously	ADV
fnp-3804	41	16	characterized	characterize	VERB
fnp-3804	41	17	oncogenic	oncogenic	ADJ
fnp-3804	41	18	drivers	driver	NOUN
fnp-3804	41	19	.	.	PUNCT
fnp-3804	42	1	the	the	DET
fnp-3804	42	2	authors	author	NOUN
fnp-3804	42	3	hypothesized	hypothesize	VERB
fnp-3804	42	4	that	that	SCONJ
fnp-3804	42	5	somatic	somatic	ADJ
fnp-3804	42	6	mutations	mutation	NOUN
fnp-3804	42	7	would	would	AUX
fnp-3804	42	8	accumulate	accumulate	VERB
fnp-3804	42	9	in	in	ADP
fnp-3804	42	10	brain	brain	NOUN
fnp-3804	42	11	tissue	tissue	NOUN
fnp-3804	42	12	over	over	ADP
fnp-3804	42	13	time	time	NOUN
fnp-3804	42	14	and	and	CCONJ
fnp-3804	42	15	(	(	PUNCT
fnp-3804	42	16	as	as	SCONJ
fnp-3804	42	17	neurons	neuron	NOUN
fnp-3804	42	18	have	have	VERB
fnp-3804	42	19	a	a	DET
fnp-3804	42	20	low	low	ADJ
fnp-3804	42	21	proliferation	proliferation	NOUN
fnp-3804	42	22	capacity	capacity	NOUN
fnp-3804	42	23	)	)	PUNCT
fnp-3804	42	24	would	would	AUX
fnp-3804	42	25	be	be	AUX
fnp-3804	42	26	enriched	enrich	VERB
fnp-3804	42	27	in	in	ADP
fnp-3804	42	28	cerebral	cerebral	ADJ
fnp-3804	42	29	white	white	ADJ
fnp-3804	42	30	matter	matter	NOUN
fnp-3804	42	31	.	.	PUNCT
fnp-3804	43	1	the	the	DET
fnp-3804	43	2	authors	author	NOUN
fnp-3804	43	3	identified	identify	VERB
fnp-3804	43	4	35	35	NUM
fnp-3804	43	5	variants	variant	NOUN
fnp-3804	43	6	present	present	ADJ
fnp-3804	43	7	in	in	ADP
fnp-3804	43	8	normal	normal	ADJ
fnp-3804	43	9	brain	brain	NOUN
fnp-3804	43	10	tissue	tissue	NOUN
fnp-3804	43	11	:	:	PUNCT
fnp-3804	43	12	12	12	NUM
fnp-3804	43	13	of	of	ADP
fnp-3804	43	14	the	the	DET
fnp-3804	43	15	variants	variant	NOUN
fnp-3804	43	16	were	be	AUX
fnp-3804	43	17	in	in	ADP
fnp-3804	43	18	known	know	VERB
fnp-3804	43	19	proto	proto	NOUN
fnp-3804	43	20	-	-	PUNCT
fnp-3804	43	21	oncogenes	oncogene	NOUN
fnp-3804	43	22	or	or	CCONJ
fnp-3804	43	23	tumor	tumor	NOUN
fnp-3804	43	24	suppressor	suppressor	NOUN
fnp-3804	43	25	genes	gene	NOUN
fnp-3804	43	26	,	,	PUNCT
fnp-3804	43	27	and	and	CCONJ
fnp-3804	43	28	6	6	NUM
fnp-3804	43	29	were	be	AUX
fnp-3804	43	30	known	know	VERB
fnp-3804	43	31	driver	driver	NOUN
fnp-3804	43	32	mutations	mutation	NOUN
fnp-3804	43	33	of	of	ADP
fnp-3804	43	34	gliomas	glioma	NOUN
fnp-3804	43	35	(	(	PUNCT
fnp-3804	43	36	idh1	idh1	PROPN
fnp-3804	43	37	,	,	PUNCT
fnp-3804	43	38	ptpn11	ptpn11	NOUN
fnp-3804	43	39	,	,	PUNCT
fnp-3804	43	40	pten	pten	VERB
fnp-3804	43	41	,	,	PUNCT
fnp-3804	43	42	nf1	nf1	NOUN
fnp-3804	43	43	,	,	PUNCT
fnp-3804	43	44	apc	apc	PROPN
fnp-3804	43	45	,	,	PUNCT
fnp-3804	43	46	mtor	mtor	PROPN
fnp-3804	43	47	)	)	PUNCT
fnp-3804	43	48	.	.	PUNCT
fnp-3804	44	1	the	the	DET
fnp-3804	44	2	authors	author	NOUN
fnp-3804	44	3	validated	validate	VERB
fnp-3804	44	4	the	the	DET
fnp-3804	44	5	variant	variant	ADJ
fnp-3804	44	6	allele	allele	NOUN
fnp-3804	44	7	frequencies	frequency	NOUN
fnp-3804	44	8	(	(	PUNCT
fnp-3804	44	9	vafs	vafs	NOUN
fnp-3804	44	10	)	)	PUNCT
fnp-3804	44	11	from	from	ADP
fnp-3804	44	12	their	their	PRON
fnp-3804	44	13	gene	gene	NOUN
fnp-3804	44	14	panel	panel	NOUN
fnp-3804	44	15	with	with	ADP
fnp-3804	44	16	ultra	ultra	ADJ
fnp-3804	44	17	-	-	ADJ
fnp-3804	44	18	deep	deep	ADJ
fnp-3804	44	19	ion	ion	NOUN
fnp-3804	44	20	torrent	torrent	NOUN
fnp-3804	44	21	sequencing	sequence	VERB
fnp-3804	44	22	.	.	PUNCT
fnp-3804	45	1	the	the	DET
fnp-3804	45	2	most	most	ADV
fnp-3804	45	3	frequently	frequently	ADV
fnp-3804	45	4	found	find	VERB
fnp-3804	45	5	mutation	mutation	NOUN
fnp-3804	45	6	was	be	AUX
fnp-3804	45	7	idh1	idh1	PROPN
fnp-3804	45	8	r132h	r132h	PROPN
fnp-3804	45	9	.	.	PUNCT
fnp-3804	46	1	in	in	ADP
fnp-3804	46	2	one	one	NUM
fnp-3804	46	3	patient	patient	NOUN
fnp-3804	46	4	,	,	PUNCT
fnp-3804	46	5	two	two	NUM
fnp-3804	46	6	adjacent	adjacent	ADJ
fnp-3804	46	7	white	white	ADJ
fnp-3804	46	8	matter	matter	NOUN
fnp-3804	46	9	samples	sample	NOUN
fnp-3804	46	10	had	have	VERB
fnp-3804	46	11	vastly	vastly	ADV
fnp-3804	46	12	different	different	ADJ
fnp-3804	46	13	variant	variant	ADJ
fnp-3804	46	14	allele	allele	NOUN
fnp-3804	46	15	frequencies	frequency	NOUN
fnp-3804	46	16	(	(	PUNCT
fnp-3804	46	17	vafs	vafs	NOUN
fnp-3804	46	18	)	)	PUNCT
fnp-3804	46	19	of	of	ADP
fnp-3804	46	20	idh1	idh1	PROPN
fnp-3804	46	21	r132h	r132h	PROPN
fnp-3804	46	22	(	(	PUNCT
fnp-3804	46	23	5	5	NUM
fnp-3804	46	24	%	%	NOUN
fnp-3804	46	25	vs	vs	ADP
fnp-3804	46	26	0.9	0.9	NUM
fnp-3804	46	27	%	%	NOUN
fnp-3804	46	28	)	)	PUNCT
fnp-3804	46	29	.	.	PUNCT
fnp-3804	47	1	because	because	SCONJ
fnp-3804	47	2	a	a	DET
fnp-3804	47	3	5	5	NUM
fnp-3804	47	4	%	%	NOUN
fnp-3804	47	5	vaf	vaf	NOUN
fnp-3804	47	6	is	be	AUX
fnp-3804	47	7	high	high	ADJ
fnp-3804	47	8	for	for	ADP
fnp-3804	47	9	a	a	DET
fnp-3804	47	10	localized	localized	ADJ
fnp-3804	47	11	oncogenic	oncogenic	ADJ
fnp-3804	47	12	mutation	mutation	NOUN
fnp-3804	47	13	,	,	PUNCT
fnp-3804	47	14	the	the	DET
fnp-3804	47	15	authors	author	NOUN
fnp-3804	47	16	suggest	suggest	VERB
fnp-3804	47	17	that	that	SCONJ
fnp-3804	47	18	in	in	ADP
fnp-3804	47	19	this	this	DET
fnp-3804	47	20	tissue	tissue	NOUN
fnp-3804	47	21	,	,	PUNCT
fnp-3804	47	22	the	the	DET
fnp-3804	47	23	mutation	mutation	NOUN
fnp-3804	47	24	should	should	AUX
fnp-3804	47	25	be	be	AUX
fnp-3804	47	26	considered	consider	VERB
fnp-3804	47	27	as	as	ADP
fnp-3804	47	28	a	a	DET
fnp-3804	47	29	clonal	clonal	ADJ
fnp-3804	47	30	event	event	NOUN
fnp-3804	47	31	that	that	PRON
fnp-3804	47	32	conferred	confer	VERB
fnp-3804	47	33	cells	cell	NOUN
fnp-3804	47	34	with	with	ADP
fnp-3804	47	35	a	a	DET
fnp-3804	47	36	proliferative	proliferative	ADJ
fnp-3804	47	37	advantage	advantage	NOUN
fnp-3804	47	38	.	.	PUNCT
fnp-3804	48	1	using	use	VERB
fnp-3804	48	2	single	single	ADJ
fnp-3804	48	3	-	-	PUNCT
fnp-3804	48	4	nucleus	nucleus	NOUN
fnp-3804	48	5	rnaseq	rnaseq	NOUN
fnp-3804	48	6	,	,	PUNCT
fnp-3804	48	7	they	they	PRON
fnp-3804	48	8	found	find	VERB
fnp-3804	48	9	that	that	SCONJ
fnp-3804	48	10	the	the	DET
fnp-3804	48	11	idh1	idh1	PROPN
fnp-3804	48	12	r132h	r132h	PROPN
fnp-3804	48	13	mutation	mutation	NOUN
fnp-3804	48	14	was	be	AUX
fnp-3804	48	15	enriched	enrich	VERB
fnp-3804	48	16	in	in	ADP
fnp-3804	48	17	glial	glial	ADJ
fnp-3804	48	18	cells	cell	NOUN
fnp-3804	48	19	.	.	PUNCT
fnp-3804	49	1	interestingly	interestingly	ADV
fnp-3804	49	2	(	(	PUNCT
fnp-3804	49	3	and	and	CCONJ
fnp-3804	49	4	thus	thus	ADV
fnp-3804	49	5	in	in	ADP
fnp-3804	49	6	contrast	contrast	NOUN
fnp-3804	49	7	to	to	ADP
fnp-3804	49	8	what	what	PRON
fnp-3804	49	9	has	have	AUX
fnp-3804	49	10	previously	previously	ADV
fnp-3804	49	11	been	be	AUX
fnp-3804	49	12	described	describe	VERB
fnp-3804	49	13	for	for	ADP
fnp-3804	49	14	other	other	ADJ
fnp-3804	49	15	organs	organ	NOUN
fnp-3804	49	16	)	)	PUNCT
fnp-3804	49	17	,	,	PUNCT
fnp-3804	49	18	in	in	ADP
fnp-3804	49	19	this	this	DET
fnp-3804	49	20	study	study	NOUN
fnp-3804	49	21	the	the	DET
fnp-3804	49	22	accumulation	accumulation	NOUN
fnp-3804	49	23	of	of	ADP
fnp-3804	49	24	oncogenic	oncogenic	ADJ
fnp-3804	49	25	mutations	mutation	NOUN
fnp-3804	49	26	in	in	ADP
fnp-3804	49	27	brain	brain	NOUN
fnp-3804	49	28	tissue	tissue	NOUN
fnp-3804	49	29	did	do	AUX
fnp-3804	49	30	not	not	PART
fnp-3804	49	31	positively	positively	ADV
fnp-3804	49	32	correlate	correlate	VERB
fnp-3804	49	33	with	with	ADP
fnp-3804	49	34	age	age	NOUN
fnp-3804	49	35	.	.	PUNCT
fnp-3804	50	1	in	in	ADP
fnp-3804	50	2	fact	fact	NOUN
fnp-3804	50	3	,	,	PUNCT
fnp-3804	50	4	all	all	PRON
fnp-3804	50	5	of	of	ADP
fnp-3804	50	6	the	the	DET
fnp-3804	50	7	patients	patient	NOUN
fnp-3804	50	8	with	with	ADP
fnp-3804	50	9	identified	identify	VERB
fnp-3804	50	10	somatic	somatic	ADJ
fnp-3804	50	11	variants	variant	NOUN
fnp-3804	50	12	were	be	AUX
fnp-3804	50	13	under	under	ADP
fnp-3804	50	14	30	30	NUM
fnp-3804	50	15	.	.	PUNCT
fnp-3804	51	1	furthermore	furthermore	ADV
fnp-3804	51	2	,	,	PUNCT
fnp-3804	51	3	in	in	ADP
fnp-3804	51	4	this	this	DET
fnp-3804	51	5	study	study	NOUN
fnp-3804	51	6	oncogenic	oncogenic	ADJ
fnp-3804	51	7	mutations	mutation	NOUN
fnp-3804	51	8	were	be	AUX
fnp-3804	51	9	found	find	VERB
fnp-3804	51	10	to	to	PART
fnp-3804	51	11	be	be	AUX
fnp-3804	51	12	present	present	ADJ
fnp-3804	51	13	in	in	ADP
fnp-3804	51	14	5.4	5.4	NUM
fnp-3804	51	15	%	%	NOUN
fnp-3804	51	16	of	of	ADP
fnp-3804	51	17	the	the	DET
fnp-3804	51	18	non	non	ADJ
fnp-3804	51	19	-	-	ADJ
fnp-3804	51	20	diseased	diseased	ADJ
fnp-3804	51	21	human	human	ADJ
fnp-3804	51	22	brains	brain	NOUN
fnp-3804	51	23	,	,	PUNCT
fnp-3804	51	24	while	while	SCONJ
fnp-3804	51	25	the	the	DET
fnp-3804	51	26	incidence	incidence	NOUN
fnp-3804	51	27	of	of	ADP
fnp-3804	51	28	primary	primary	ADJ
fnp-3804	51	29	brain	brain	NOUN
fnp-3804	51	30	tumors	tumor	NOUN
fnp-3804	51	31	in	in	ADP
fnp-3804	51	32	the	the	DET
fnp-3804	51	33	population	population	NOUN
fnp-3804	51	34	is	be	AUX
fnp-3804	51	35	much	much	ADV
fnp-3804	51	36	lower	low	ADJ
fnp-3804	51	37	.	.	PUNCT
fnp-3804	52	1	these	these	DET
fnp-3804	52	2	results	result	NOUN
fnp-3804	52	3	thus	thus	ADV
fnp-3804	52	4	raise	raise	VERB
fnp-3804	52	5	some	some	DET
fnp-3804	52	6	intriguing	intriguing	ADJ
fnp-3804	52	7	next	next	ADJ
fnp-3804	52	8	questions	question	NOUN
fnp-3804	52	9	,	,	PUNCT
fnp-3804	52	10	such	such	ADJ
fnp-3804	52	11	as	as	ADP
fnp-3804	52	12	:	:	PUNCT
fnp-3804	52	13	what	what	PRON
fnp-3804	52	14	are	be	AUX
fnp-3804	52	15	the	the	DET
fnp-3804	52	16	mechanisms	mechanism	NOUN
fnp-3804	52	17	for	for	ADP
fnp-3804	52	18	postnatal	postnatal	ADJ
fnp-3804	52	19	elimination	elimination	NOUN
fnp-3804	52	20	of	of	ADP
fnp-3804	52	21	the	the	DET
fnp-3804	52	22	mutant	mutant	ADJ
fnp-3804	52	23	clones	clone	NOUN
fnp-3804	52	24	?	?	PUNCT
fnp-3804	53	1	what	what	PRON
fnp-3804	53	2	is	be	AUX
fnp-3804	53	3	the	the	DET
fnp-3804	53	4	‘	'	PUNCT
fnp-3804	53	5	tipping	tipping	ADJ
fnp-3804	53	6	point	point	NOUN
fnp-3804	53	7	’	'	PUNCT
fnp-3804	53	8	that	that	PRON
fnp-3804	53	9	eventually	eventually	ADV
fnp-3804	53	10	causes	cause	VERB
fnp-3804	53	11	brain	brain	NOUN
fnp-3804	53	12	tumor	tumor	NOUN
fnp-3804	53	13	formation	formation	NOUN
fnp-3804	53	14	?	?	PUNCT
fnp-3804	54	1	maybe	maybe	ADV
fnp-3804	54	2	the	the	DET
fnp-3804	54	3	acquisition	acquisition	NOUN
fnp-3804	54	4	of	of	ADP
fnp-3804	54	5	a	a	DET
fnp-3804	54	6	second	second	ADJ
fnp-3804	54	7	hit	hit	NOUN
fnp-3804	54	8	(	(	PUNCT
fnp-3804	54	9	such	such	ADJ
fnp-3804	54	10	as	as	ADP
fnp-3804	54	11	tp53	tp53	PROPN
fnp-3804	54	12	and/or	and/or	CCONJ
fnp-3804	54	13	atrx	atrx	VERB
fnp-3804	54	14	mutation	mutation	NOUN
fnp-3804	54	15	for	for	ADP
fnp-3804	54	16	idh	idh	NOUN
fnp-3804	54	17	-	-	PUNCT
fnp-3804	54	18	mutant	mutant	NOUN
fnp-3804	54	19	astrocytomas	astrocytoma	NOUN
fnp-3804	54	20	,	,	PUNCT
fnp-3804	54	21	and	and	CCONJ
fnp-3804	54	22	1p/19q	1p/19q	NOUN
fnp-3804	54	23	codeletion	codeletion	NOUN
fnp-3804	54	24	for	for	ADP
fnp-3804	54	25	idh	idh	NOUN
fnp-3804	54	26	-	-	PUNCT
fnp-3804	54	27	mutant	mutant	NOUN
fnp-3804	54	28	oligodendrogliomas	oligodendroglioma	NOUN
fnp-3804	54	29	)	)	PUNCT
fnp-3804	54	30	17	17	NUM
fnp-3804	54	31	?	?	PUNCT
fnp-3804	55	1	and	and	CCONJ
fnp-3804	55	2	do	do	AUX
fnp-3804	55	3	maybe	maybe	ADV
fnp-3804	55	4	these	these	DET
fnp-3804	55	5	findings	finding	NOUN
fnp-3804	55	6	help	help	VERB
fnp-3804	55	7	to	to	PART
fnp-3804	55	8	explain	explain	VERB
fnp-3804	55	9	the	the	DET
fnp-3804	55	10	occurrence	occurrence	NOUN
fnp-3804	55	11	of	of	ADP
fnp-3804	55	12	‘	'	PUNCT
fnp-3804	55	13	dual	dual	ADJ
fnp-3804	55	14	genotype	genotype	NOUN
fnp-3804	55	15	’	'	PUNCT
fnp-3804	55	16	oligoastrocytomas	oligoastrocytoma	NOUN
fnp-3804	55	17	with	with	ADP
fnp-3804	55	18	histologically	histologically	ADV
fnp-3804	55	19	distinct	distinct	ADJ
fnp-3804	55	20	astrocytic	astrocytic	ADJ
fnp-3804	55	21	and	and	CCONJ
fnp-3804	55	22	oligodendroglial	oligodendroglial	ADJ
fnp-3804	55	23	areas	area	NOUN
fnp-3804	55	24	18	18	NUM
fnp-3804	55	25	?	?	PUNCT
fnp-3804	55	26	topic	topic	NOUN
fnp-3804	55	27	3	3	NUM
fnp-3804	55	28	:	:	PUNCT
fnp-3804	55	29	neuronal	neuronal	ADJ
fnp-3804	55	30	activity	activity	NOUN
fnp-3804	55	31	-	-	PUNCT
fnp-3804	55	32	dependent	dependent	ADJ
fnp-3804	55	33	initiation	initiation	NOUN
fnp-3804	55	34	of	of	ADP
fnp-3804	55	35	nf1	nf1	NOUN
fnp-3804	55	36	-	-	PUNCT
fnp-3804	55	37	mutant	mutant	ADJ
fnp-3804	55	38	‘	'	PUNCT
fnp-3804	55	39	optic	optic	ADJ
fnp-3804	55	40	gliomas	glioma	NOUN
fnp-3804	55	41	’	'	PUNCT
fnp-3804	55	42	3	3	NUM
fnp-3804	55	43	over	over	ADP
fnp-3804	55	44	the	the	DET
fnp-3804	55	45	past	past	ADJ
fnp-3804	55	46	few	few	ADJ
fnp-3804	55	47	years	year	NOUN
fnp-3804	55	48	,	,	PUNCT
fnp-3804	55	49	we	we	PRON
fnp-3804	55	50	have	have	AUX
fnp-3804	55	51	begun	begin	VERB
fnp-3804	55	52	to	to	PART
fnp-3804	55	53	appreciate	appreciate	VERB
fnp-3804	55	54	the	the	DET
fnp-3804	55	55	unique	unique	ADJ
fnp-3804	55	56	role	role	NOUN
fnp-3804	55	57	of	of	ADP
fnp-3804	55	58	neurons	neuron	NOUN
fnp-3804	55	59	for	for	ADP
fnp-3804	55	60	glioma	glioma	NOUN
fnp-3804	55	61	growth	growth	NOUN
fnp-3804	55	62	.	.	PUNCT
fnp-3804	56	1	for	for	ADP
fnp-3804	56	2	example	example	NOUN
fnp-3804	56	3	,	,	PUNCT
fnp-3804	56	4	two	two	NUM
fnp-3804	56	5	papers	paper	NOUN
fnp-3804	56	6	that	that	PRON
fnp-3804	56	7	were	be	AUX
fnp-3804	56	8	already	already	ADV
fnp-3804	56	9	summarized	summarize	VERB
fnp-3804	56	10	in	in	ADP
fnp-3804	56	11	topic	topic	NOUN
fnp-3804	56	12	7	7	NUM
fnp-3804	56	13	of	of	ADP
fnp-3804	56	14	the	the	DET
fnp-3804	56	15	‘	'	PUNCT
fnp-3804	56	16	top	top	ADJ
fnp-3804	56	17	ten	ten	NUM
fnp-3804	56	18	discoveries	discovery	NOUN
fnp-3804	56	19	in	in	ADP
fnp-3804	56	20	2019	2019	NUM
fnp-3804	56	21	’	'	PUNCT
fnp-3804	56	22	review	review	NOUN
fnp-3804	56	23	in	in	ADP
fnp-3804	56	24	this	this	DET
fnp-3804	56	25	journal	journal	NOUN
fnp-3804	56	26	demonstrated	demonstrate	VERB
fnp-3804	56	27	the	the	DET
fnp-3804	56	28	presence	presence	NOUN
fnp-3804	56	29	of	of	ADP
fnp-3804	56	30	bona	bona	ADJ
fnp-3804	56	31	fide	fide	ADJ
fnp-3804	56	32	neuron	neuron	NOUN
fnp-3804	56	33	-	-	PUNCT
fnp-3804	56	34	glioma	glioma	NOUN
fnp-3804	56	35	synapses	synapsis	NOUN
fnp-3804	56	36	in	in	ADP
fnp-3804	56	37	high	high	ADJ
fnp-3804	56	38	-	-	PUNCT
fnp-3804	56	39	grade	grade	NOUN
fnp-3804	56	40	gliomas	glioma	NOUN
fnp-3804	56	41	,	,	PUNCT
fnp-3804	56	42	with	with	ADP
fnp-3804	56	43	electrochemical	electrochemical	ADJ
fnp-3804	56	44	-	-	PUNCT
fnp-3804	56	45	induced	induce	VERB
fnp-3804	56	46	depolarization	depolarization	NOUN
fnp-3804	56	47	of	of	ADP
fnp-3804	56	48	the	the	DET
fnp-3804	56	49	glioma	glioma	NOUN
fnp-3804	56	50	membrane	membrane	NOUN
fnp-3804	56	51	promoting	promote	VERB
fnp-3804	56	52	proliferation	proliferation	NOUN
fnp-3804	56	53	of	of	ADP
fnp-3804	56	54	the	the	DET
fnp-3804	56	55	tumor	tumor	NOUN
fnp-3804	56	56	cells	cell	NOUN
fnp-3804	56	57	19,20	19,20	NOUN
fnp-3804	56	58	.	.	PUNCT
fnp-3804	57	1	these	these	DET
fnp-3804	57	2	discoveries	discovery	NOUN
fnp-3804	57	3	have	have	AUX
fnp-3804	57	4	boosted	boost	VERB
fnp-3804	57	5	the	the	DET
fnp-3804	57	6	interdisciplinary	interdisciplinary	ADJ
fnp-3804	57	7	field	field	NOUN
fnp-3804	57	8	of	of	ADP
fnp-3804	57	9	‘	'	PUNCT
fnp-3804	57	10	cancer	cancer	NOUN
fnp-3804	57	11	neuroscience	neuroscience	NOUN
fnp-3804	57	12	’	'	PUNCT
fnp-3804	57	13	21	21	NUM
fnp-3804	57	14	.	.	PUNCT
fnp-3804	57	15	therapies	therapy	NOUN
fnp-3804	57	16	that	that	PRON
fnp-3804	57	17	target	target	VERB
fnp-3804	57	18	the	the	DET
fnp-3804	57	19	neuron	neuron	NOUN
fnp-3804	57	20	-	-	PUNCT
fnp-3804	57	21	glioma	glioma	NOUN
fnp-3804	57	22	interface	interface	NOUN
fnp-3804	57	23	,	,	PUNCT
fnp-3804	57	24	especially	especially	ADV
fnp-3804	57	25	through	through	ADP
fnp-3804	57	26	neuroligin-3	neuroligin-3	PRON
fnp-3804	57	27	signaling	signal	VERB
fnp-3804	57	28	(	(	PUNCT
fnp-3804	57	29	nlgn3	nlgn3	ADJ
fnp-3804	57	30	)	)	PUNCT
fnp-3804	57	31	,	,	PUNCT
fnp-3804	57	32	are	be	AUX
fnp-3804	57	33	now	now	ADV
fnp-3804	57	34	under	under	ADP
fnp-3804	57	35	investigation	investigation	NOUN
fnp-3804	57	36	as	as	ADP
fnp-3804	57	37	a	a	DET
fnp-3804	57	38	possible	possible	ADJ
fnp-3804	57	39	treatment	treatment	NOUN
fnp-3804	57	40	for	for	ADP
fnp-3804	57	41	these	these	DET
fnp-3804	57	42	malignant	malignant	ADJ
fnp-3804	57	43	gliomas	glioma	NOUN
fnp-3804	57	44	22,23	22,23	NOUN
fnp-3804	57	45	.	.	PUNCT
fnp-3804	58	1	in	in	ADP
fnp-3804	58	2	2021	2021	NUM
fnp-3804	58	3	,	,	PUNCT
fnp-3804	58	4	pan	pan	VERB
fnp-3804	58	5	y	y	PROPN
fnp-3804	58	6	et	et	PROPN
fnp-3804	58	7	al	al	PROPN
fnp-3804	58	8	.	.	PUNCT
fnp-3804	59	1	(	(	PUNCT
fnp-3804	59	2	with	with	ADP
fnp-3804	59	3	monje	monje	PROPN
fnp-3804	59	4	m	m	PROPN
fnp-3804	59	5	and	and	CCONJ
fnp-3804	59	6	gutmann	gutmann	PROPN
fnp-3804	59	7	dh	dh	PROPN
fnp-3804	59	8	as	as	ADP
fnp-3804	59	9	corresponding	corresponding	ADJ
fnp-3804	59	10	authors	author	NOUN
fnp-3804	59	11	)	)	PUNCT
fnp-3804	59	12	published	publish	VERB
fnp-3804	59	13	a	a	DET
fnp-3804	59	14	study	study	NOUN
fnp-3804	59	15	in	in	ADP
fnp-3804	59	16	nature	nature	NOUN
fnp-3804	59	17	on	on	ADP
fnp-3804	59	18	the	the	DET
fnp-3804	59	19	impact	impact	NOUN
fnp-3804	59	20	of	of	ADP
fnp-3804	59	21	neuronal	neuronal	ADJ
fnp-3804	59	22	activity	activity	NOUN
fnp-3804	59	23	in	in	ADP
fnp-3804	59	24	the	the	DET
fnp-3804	59	25	optic	optic	NOUN
fnp-3804	59	26	nerve	nerve	NOUN
fnp-3804	59	27	on	on	ADP
fnp-3804	59	28	the	the	DET
fnp-3804	59	29	formation	formation	NOUN
fnp-3804	59	30	and	and	CCONJ
fnp-3804	59	31	growth	growth	NOUN
fnp-3804	59	32	of	of	ADP
fnp-3804	59	33	‘	'	PUNCT
fnp-3804	59	34	optic	optic	ADJ
fnp-3804	59	35	gliomas	glioma	NOUN
fnp-3804	59	36	’	'	PUNCT
fnp-3804	59	37	in	in	ADP
fnp-3804	59	38	mice	mouse	NOUN
fnp-3804	59	39	with	with	ADP
fnp-3804	59	40	nf1	nf1	NOUN
fnp-3804	59	41	mutation	mutation	NOUN
fnp-3804	59	42	3	3	X
fnp-3804	59	43	.	.	PUNCT
fnp-3804	60	1	the	the	DET
fnp-3804	60	2	authors	author	NOUN
fnp-3804	60	3	started	start	VERB
fnp-3804	60	4	with	with	ADP
fnp-3804	60	5	an	an	DET
fnp-3804	60	6	authenticated	authenticate	VERB
fnp-3804	60	7	genetically	genetically	ADV
fnp-3804	60	8	engineered	engineer	VERB
fnp-3804	60	9	mouse	mouse	NOUN
fnp-3804	60	10	model	model	NOUN
fnp-3804	60	11	which	which	PRON
fnp-3804	60	12	mimics	mimic	VERB
fnp-3804	60	13	the	the	DET
fnp-3804	60	14	neurofibromatosis	neurofibromatosis	NOUN
fnp-3804	60	15	type	type	NOUN
fnp-3804	60	16	1	1	NUM
fnp-3804	60	17	(	(	PUNCT
fnp-3804	60	18	nf1	nf1	NOUN
fnp-3804	60	19	)	)	PUNCT
fnp-3804	60	20	childhood	childhood	NOUN
fnp-3804	60	21	predisposition	predisposition	NOUN
fnp-3804	60	22	syndrome	syndrome	NOUN
fnp-3804	60	23	:	:	PUNCT
fnp-3804	60	24	a	a	DET
fnp-3804	60	25	germline	germline	NOUN
fnp-3804	60	26	nf1	nf1	NOUN
fnp-3804	60	27	mutation	mutation	NOUN
fnp-3804	60	28	(	(	PUNCT
fnp-3804	60	29	nf1+/-	nf1+/-	PROPN
fnp-3804	60	30	)	)	PUNCT
fnp-3804	60	31	combined	combine	VERB
fnp-3804	60	32	with	with	ADP
fnp-3804	60	33	an	an	DET
fnp-3804	60	34	acquired	acquire	VERB
fnp-3804	60	35	somatic	somatic	ADJ
fnp-3804	60	36	nf1	nf1	NOUN
fnp-3804	60	37	mutation	mutation	NOUN
fnp-3804	60	38	in	in	ADP
fnp-3804	60	39	neural	neural	ADJ
fnp-3804	60	40	progenitor	progenitor	NOUN
fnp-3804	60	41	cells	cell	NOUN
fnp-3804	60	42	(	(	PUNCT
fnp-3804	60	43	nf1-/-	nf1-/-	PROPN
fnp-3804	60	44	)	)	PUNCT
fnp-3804	60	45	.	.	PUNCT
fnp-3804	61	1	when	when	SCONJ
fnp-3804	61	2	these	these	DET
fnp-3804	61	3	mice	mouse	NOUN
fnp-3804	61	4	are	be	AUX
fnp-3804	61	5	9	9	NUM
fnp-3804	61	6	weeks	week	NOUN
fnp-3804	61	7	of	of	ADP
fnp-3804	61	8	age	age	NOUN
fnp-3804	61	9	,	,	PUNCT
fnp-3804	61	10	gliomas	glioma	NOUN
fnp-3804	61	11	form	form	VERB
fnp-3804	61	12	along	along	ADP
fnp-3804	61	13	the	the	DET
fnp-3804	61	14	optic	optic	NOUN
fnp-3804	61	15	nerve	nerve	NOUN
fnp-3804	61	16	,	,	PUNCT
fnp-3804	61	17	resembling	resemble	VERB
fnp-3804	61	18	what	what	PRON
fnp-3804	61	19	is	be	AUX
fnp-3804	61	20	seen	see	VERB
fnp-3804	61	21	in	in	ADP
fnp-3804	61	22	children	child	NOUN
fnp-3804	61	23	with	with	ADP
fnp-3804	61	24	nf1	nf1	NOUN
fnp-3804	61	25	(	(	PUNCT
fnp-3804	61	26	and	and	CCONJ
fnp-3804	61	27	in	in	ADP
fnp-3804	61	28	the	the	DET
fnp-3804	61	29	vocabulary	vocabulary	NOUN
fnp-3804	61	30	of	of	ADP
fnp-3804	61	31	the	the	PRON
fnp-3804	61	32	who	who	PRON
fnp-3804	61	33	cns	cns	VERB
fnp-3804	61	34	tumor	tumor	NOUN
fnp-3804	61	35	classification	classification	NOUN
fnp-3804	61	36	then	then	ADV
fnp-3804	61	37	generally	generally	ADV
fnp-3804	61	38	concern	concern	ADJ
fnp-3804	61	39	pilocytic	pilocytic	ADJ
fnp-3804	61	40	astrocytomas	astrocytoma	NOUN
fnp-3804	61	41	)	)	PUNCT
fnp-3804	61	42	.	.	PUNCT
fnp-3804	62	1	by	by	ADP
fnp-3804	62	2	stimulating	stimulate	VERB
fnp-3804	62	3	the	the	DET
fnp-3804	62	4	retinal	retinal	ADJ
fnp-3804	62	5	ganglion	ganglion	NOUN
fnp-3804	62	6	cells	cell	NOUN
fnp-3804	62	7	,	,	PUNCT
fnp-3804	62	8	the	the	DET
fnp-3804	62	9	authors	author	NOUN
fnp-3804	62	10	found	find	VERB
fnp-3804	62	11	an	an	DET
fnp-3804	62	12	increase	increase	NOUN
fnp-3804	62	13	in	in	ADP
fnp-3804	62	14	optic	optic	ADJ
fnp-3804	62	15	nerve	nerve	NOUN
fnp-3804	62	16	volume	volume	NOUN
fnp-3804	62	17	and	and	CCONJ
fnp-3804	62	18	proliferation	proliferation	NOUN
fnp-3804	62	19	rate	rate	NOUN
fnp-3804	62	20	,	,	PUNCT
fnp-3804	62	21	proving	prove	VERB
fnp-3804	62	22	that	that	SCONJ
fnp-3804	62	23	optic	optic	ADJ
fnp-3804	62	24	nerve	nerve	NOUN
fnp-3804	62	25	activity	activity	NOUN
fnp-3804	62	26	can	can	AUX
fnp-3804	62	27	increase	increase	VERB
fnp-3804	62	28	optic	optic	ADJ
fnp-3804	62	29	glioma	glioma	NOUN
fnp-3804	62	30	growth	growth	NOUN
fnp-3804	62	31	.	.	PUNCT
fnp-3804	63	1	next	next	ADV
fnp-3804	63	2	,	,	PUNCT
fnp-3804	63	3	the	the	DET
fnp-3804	63	4	authors	author	NOUN
fnp-3804	63	5	investigated	investigate	VERB
fnp-3804	63	6	the	the	DET
fnp-3804	63	7	effect	effect	NOUN
fnp-3804	63	8	of	of	ADP
fnp-3804	63	9	visual	visual	ADJ
fnp-3804	63	10	experience	experience	NOUN
fnp-3804	63	11	on	on	ADP
fnp-3804	63	12	the	the	DET
fnp-3804	63	13	initiation	initiation	NOUN
fnp-3804	63	14	and	and	CCONJ
fnp-3804	63	15	growth	growth	NOUN
fnp-3804	63	16	of	of	ADP
fnp-3804	63	17	these	these	DET
fnp-3804	63	18	optic	optic	ADJ
fnp-3804	63	19	gliomas	glioma	NOUN
fnp-3804	63	20	.	.	PUNCT
fnp-3804	64	1	rearing	rear	VERB
fnp-3804	64	2	mice	mouse	NOUN
fnp-3804	64	3	in	in	ADP
fnp-3804	64	4	the	the	DET
fnp-3804	64	5	dark	dark	NOUN
fnp-3804	64	6	from	from	ADP
fnp-3804	64	7	6	6	NUM
fnp-3804	64	8	weeks	week	NOUN
fnp-3804	64	9	of	of	ADP
fnp-3804	64	10	age	age	NOUN
fnp-3804	64	11	(	(	PUNCT
fnp-3804	64	12	before	before	ADP
fnp-3804	64	13	optic	optic	ADJ
fnp-3804	64	14	glioma	glioma	NOUN
fnp-3804	64	15	formation	formation	NOUN
fnp-3804	64	16	)	)	PUNCT
fnp-3804	64	17	prevented	prevent	VERB
fnp-3804	64	18	the	the	DET
fnp-3804	64	19	formation	formation	NOUN
fnp-3804	64	20	of	of	ADP
fnp-3804	64	21	tumors	tumor	NOUN
fnp-3804	64	22	.	.	PUNCT
fnp-3804	65	1	additionally	additionally	ADV
fnp-3804	65	2	,	,	PUNCT
fnp-3804	65	3	compared	compare	VERB
fnp-3804	65	4	with	with	ADP
fnp-3804	65	5	mice	mouse	NOUN
fnp-3804	65	6	raised	raise	VERB
fnp-3804	65	7	in	in	ADP
fnp-3804	65	8	a	a	DET
fnp-3804	65	9	regular	regular	ADJ
fnp-3804	65	10	light	light	ADJ
fnp-3804	65	11	cycle	cycle	NOUN
fnp-3804	65	12	,	,	PUNCT
fnp-3804	65	13	dark	dark	ADV
fnp-3804	65	14	-	-	PUNCT
fnp-3804	65	15	rearing	rear	VERB
fnp-3804	65	16	mice	mouse	NOUN
fnp-3804	65	17	rescued	rescue	VERB
fnp-3804	65	18	retinal	retinal	ADJ
fnp-3804	65	19	ganglion	ganglion	NOUN
fnp-3804	65	20	cell	cell	NOUN
fnp-3804	65	21	death	death	NOUN
fnp-3804	65	22	and	and	CCONJ
fnp-3804	65	23	prevented	prevent	VERB
fnp-3804	65	24	optic	optic	ADJ
fnp-3804	65	25	nerve	nerve	NOUN
fnp-3804	65	26	damage	damage	NOUN
fnp-3804	65	27	.	.	PUNCT
fnp-3804	66	1	pan	pan	NOUN
fnp-3804	66	2	y	y	PROPN
fnp-3804	66	3	et	et	PROPN
fnp-3804	66	4	al	al	PROPN
fnp-3804	66	5	.	.	PROPN
fnp-3804	66	6	further	further	PROPN
fnp-3804	66	7	characterized	characterize	VERB
fnp-3804	66	8	the	the	DET
fnp-3804	66	9	role	role	NOUN
fnp-3804	66	10	of	of	ADP
fnp-3804	66	11	nlgn3	nlgn3	PROPN
fnp-3804	66	12	,	,	PUNCT
fnp-3804	66	13	a	a	DET
fnp-3804	66	14	synaptic	synaptic	ADJ
fnp-3804	66	15	adhesion	adhesion	NOUN
fnp-3804	66	16	molecule	molecule	NOUN
fnp-3804	66	17	,	,	PUNCT
fnp-3804	66	18	in	in	ADP
fnp-3804	66	19	these	these	DET
fnp-3804	66	20	models	model	NOUN
fnp-3804	66	21	and	and	CCONJ
fnp-3804	66	22	found	find	VERB
fnp-3804	66	23	that	that	SCONJ
fnp-3804	66	24	it	it	PRON
fnp-3804	66	25	operates	operate	VERB
fnp-3804	66	26	under	under	ADP
fnp-3804	66	27	a	a	DET
fnp-3804	66	28	similar	similar	ADJ
fnp-3804	66	29	mechanism	mechanism	NOUN
fnp-3804	66	30	as	as	ADP
fnp-3804	66	31	in	in	ADP
fnp-3804	66	32	high	high	ADJ
fnp-3804	66	33	-	-	PUNCT
fnp-3804	66	34	grade	grade	NOUN
fnp-3804	66	35	gliomas	glioma	NOUN
fnp-3804	66	36	:	:	PUNCT
fnp-3804	66	37	adam10	adam10	NOUN
fnp-3804	66	38	sheddase	sheddase	VERB
fnp-3804	66	39	cleaves	cleave	VERB
fnp-3804	66	40	and	and	CCONJ
fnp-3804	66	41	releases	release	VERB
fnp-3804	66	42	nlgn3	nlgn3	ADJ
fnp-3804	66	43	into	into	ADP
fnp-3804	66	44	in	in	ADP
fnp-3804	66	45	the	the	DET
fnp-3804	66	46	tumor	tumor	NOUN
fnp-3804	66	47	microenvironment	microenvironment	NOUN
fnp-3804	66	48	,	,	PUNCT
fnp-3804	66	49	which	which	PRON
fnp-3804	66	50	stimulates	stimulate	VERB
fnp-3804	66	51	proliferation	proliferation	NOUN
fnp-3804	66	52	of	of	ADP
fnp-3804	66	53	optic	optic	ADJ
fnp-3804	66	54	glioma	glioma	NOUN
fnp-3804	66	55	cells	cell	NOUN
fnp-3804	66	56	.	.	PUNCT
fnp-3804	67	1	when	when	SCONJ
fnp-3804	67	2	the	the	DET
fnp-3804	67	3	authors	author	NOUN
fnp-3804	67	4	introduced	introduce	VERB
fnp-3804	67	5	a	a	DET
fnp-3804	67	6	brain	brain	NOUN
fnp-3804	67	7	penetrant	penetrant	NOUN
fnp-3804	67	8	inhibitor	inhibitor	NOUN
fnp-3804	67	9	of	of	ADP
fnp-3804	67	10	adam10	adam10	NOUN
fnp-3804	67	11	in	in	ADP
fnp-3804	67	12	their	their	PRON
fnp-3804	67	13	model	model	NOUN
fnp-3804	67	14	,	,	PUNCT
fnp-3804	67	15	no	no	DET
fnp-3804	67	16	tumor	tumor	NOUN
fnp-3804	67	17	formed	form	VERB
fnp-3804	67	18	in	in	ADP
fnp-3804	67	19	the	the	DET
fnp-3804	67	20	optic	optic	NOUN
fnp-3804	67	21	nerve	nerve	NOUN
fnp-3804	67	22	.	.	PUNCT
fnp-3804	68	1	these	these	DET
fnp-3804	68	2	insights	insight	NOUN
fnp-3804	68	3	raise	raise	VERB
fnp-3804	68	4	many	many	ADJ
fnp-3804	68	5	interesting	interesting	ADJ
fnp-3804	68	6	follow	follow	VERB
fnp-3804	68	7	up	up	ADP
fnp-3804	68	8	questions	question	NOUN
fnp-3804	68	9	.	.	PUNCT
fnp-3804	69	1	for	for	ADP
fnp-3804	69	2	example	example	NOUN
fnp-3804	69	3	,	,	PUNCT
fnp-3804	69	4	would	would	AUX
fnp-3804	69	5	limiting	limit	VERB
fnp-3804	69	6	light	light	ADJ
fnp-3804	69	7	exposure	exposure	NOUN
fnp-3804	69	8	—	—	PUNCT
fnp-3804	69	9	e.g.	e.g.	ADV
fnp-3804	69	10	,	,	PUNCT
fnp-3804	69	11	with	with	ADP
fnp-3804	69	12	light	light	ADJ
fnp-3804	69	13	-	-	PUNCT
fnp-3804	69	14	blocking	block	VERB
fnp-3804	69	15	glasses	glass	NOUN
fnp-3804	69	16	—	—	PUNCT
fnp-3804	69	17	and/or	and/or	CCONJ
fnp-3804	69	18	interference	interference	VERB
fnp-3804	69	19	with	with	ADP
fnp-3804	69	20	nlgn3	nlgn3	NOUN
fnp-3804	69	21	during	during	ADP
fnp-3804	69	22	certain	certain	ADJ
fnp-3804	69	23	developmental	developmental	ADJ
fnp-3804	69	24	periods	period	NOUN
fnp-3804	69	25	in	in	ADP
fnp-3804	69	26	children	child	NOUN
fnp-3804	69	27	help	help	VERB
fnp-3804	69	28	to	to	PART
fnp-3804	69	29	prevent	prevent	VERB
fnp-3804	69	30	optic	optic	ADJ
fnp-3804	69	31	glioma	glioma	NOUN
fnp-3804	69	32	formation	formation	NOUN
fnp-3804	69	33	?	?	PUNCT
fnp-3804	70	1	hopefully	hopefully	ADV
fnp-3804	70	2	,	,	PUNCT
fnp-3804	70	3	these	these	DET
fnp-3804	70	4	findings	finding	NOUN
fnp-3804	70	5	will	will	AUX
fnp-3804	70	6	sooner	soon	ADV
fnp-3804	70	7	or	or	CCONJ
fnp-3804	70	8	later	later	ADV
fnp-3804	70	9	provide	provide	VERB
fnp-3804	70	10	new	new	ADJ
fnp-3804	70	11	opportunities	opportunity	NOUN
fnp-3804	70	12	for	for	ADP
fnp-3804	70	13	the	the	DET
fnp-3804	70	14	therapeutic	therapeutic	ADJ
fnp-3804	70	15	management	management	NOUN
fnp-3804	70	16	of	of	ADP
fnp-3804	70	17	children	child	NOUN
fnp-3804	70	18	with	with	ADP
fnp-3804	70	19	nf1	nf1	NOUN
fnp-3804	70	20	.	.	PUNCT
fnp-3804	71	1	topic	topic	NOUN
fnp-3804	71	2	4	4	NUM
fnp-3804	71	3	:	:	PUNCT
fnp-3804	71	4	oncogenic	oncogenic	ADJ
fnp-3804	71	5	role	role	NOUN
fnp-3804	71	6	of	of	ADP
fnp-3804	71	7	h3	h3	NOUN
fnp-3804	71	8	mutations	mutation	NOUN
fnp-3804	71	9	in	in	ADP
fnp-3804	71	10	histogenesis	histogenesis	ADJ
fnp-3804	71	11	context	context	NOUN
fnp-3804	71	12	4,5	4,5	NUM
fnp-3804	71	13	mutations	mutation	NOUN
fnp-3804	71	14	affecting	affect	VERB
fnp-3804	71	15	histone	histone	NOUN
fnp-3804	71	16	h3	h3	NOUN
fnp-3804	71	17	are	be	AUX
fnp-3804	71	18	a	a	DET
fnp-3804	71	19	defining	define	VERB
fnp-3804	71	20	feature	feature	NOUN
fnp-3804	71	21	in	in	ADP
fnp-3804	71	22	a	a	DET
fnp-3804	71	23	particular	particular	ADJ
fnp-3804	71	24	subset	subset	NOUN
fnp-3804	71	25	of	of	ADP
fnp-3804	71	26	high	high	ADJ
fnp-3804	71	27	-	-	PUNCT
fnp-3804	71	28	grade	grade	NOUN
fnp-3804	71	29	diffuse	diffuse	NOUN
fnp-3804	71	30	gliomas	glioma	NOUN
fnp-3804	71	31	in	in	ADP
fnp-3804	71	32	children	child	NOUN
fnp-3804	71	33	and	and	CCONJ
fnp-3804	71	34	suggest	suggest	VERB
fnp-3804	71	35	an	an	DET
fnp-3804	71	36	epigenetic	epigenetic	ADJ
fnp-3804	71	37	driver	driver	NOUN
fnp-3804	71	38	of	of	ADP
fnp-3804	71	39	cancer	cancer	NOUN
fnp-3804	71	40	.	.	PUNCT
fnp-3804	72	1	the	the	DET
fnp-3804	72	2	two	two	NUM
fnp-3804	72	3	more	more	ADV
fnp-3804	72	4	common	common	ADJ
fnp-3804	72	5	mutations	mutation	NOUN
fnp-3804	72	6	,	,	PUNCT
fnp-3804	72	7	h3.3	h3.3	NOUN
fnp-3804	72	8	p.k28	p.k28	PROPN
fnp-3804	72	9	m	m	PROPN
fnp-3804	72	10	(	(	PUNCT
fnp-3804	72	11	k27	k27	PROPN
fnp-3804	72	12	m	m	PROPN
fnp-3804	72	13	)	)	PUNCT
fnp-3804	72	14	and	and	CCONJ
fnp-3804	72	15	h3.3	h3.3	NOUN
fnp-3804	72	16	p.g35r	p.g35r	PROPN
fnp-3804	72	17	/	/	SYM
fnp-3804	72	18	v	v	NOUN
fnp-3804	72	19	(	(	PUNCT
fnp-3804	72	20	g34r	g34r	NOUN
fnp-3804	72	21	/	/	SYM
fnp-3804	72	22	v	v	NOUN
fnp-3804	72	23	)	)	PUNCT
fnp-3804	72	24	,	,	PUNCT
fnp-3804	72	25	are	be	AUX
fnp-3804	72	26	mutually	mutually	ADV
fnp-3804	72	27	exclusive	exclusive	ADJ
fnp-3804	72	28	and	and	CCONJ
fnp-3804	72	29	typically	typically	ADV
fnp-3804	72	30	lead	lead	VERB
fnp-3804	72	31	to	to	ADP
fnp-3804	72	32	tumor	tumor	NOUN
fnp-3804	72	33	formation	formation	NOUN
fnp-3804	72	34	in	in	ADP
fnp-3804	72	35	different	different	ADJ
fnp-3804	72	36	cns	cns	NOUN
fnp-3804	72	37	locations	location	NOUN
fnp-3804	72	38	(	(	PUNCT
fnp-3804	72	39	h3	h3	VERB
fnp-3804	72	40	k27	k27	PROPN
fnp-3804	72	41	m	m	PROPN
fnp-3804	72	42	in	in	ADP
fnp-3804	72	43	midline	midline	NOUN
fnp-3804	72	44	structures	structure	NOUN
fnp-3804	72	45	,	,	PUNCT
fnp-3804	72	46	and	and	CCONJ
fnp-3804	72	47	h3	h3	VERB
fnp-3804	72	48	g34r	g34r	NOUN
fnp-3804	72	49	/	/	SYM
fnp-3804	72	50	v	v	NOUN
fnp-3804	72	51	in	in	ADP
fnp-3804	72	52	the	the	DET
fnp-3804	72	53	cerebral	cerebral	ADJ
fnp-3804	72	54	hemisphere	hemisphere	ADV
fnp-3804	72	55	)	)	PUNCT
fnp-3804	72	56	.	.	PUNCT
fnp-3804	73	1	two	two	NUM
fnp-3804	73	2	recent	recent	ADJ
fnp-3804	73	3	studies	study	NOUN
fnp-3804	73	4	aimed	aim	VERB
fnp-3804	73	5	to	to	PART
fnp-3804	73	6	discern	discern	VERB
fnp-3804	73	7	the	the	DET
fnp-3804	73	8	oncogenic	oncogenic	ADJ
fnp-3804	73	9	mechanisms	mechanism	NOUN
fnp-3804	73	10	of	of	ADP
fnp-3804	73	11	these	these	DET
fnp-3804	73	12	h3.3	h3.3	NOUN
fnp-3804	73	13	mutations	mutation	NOUN
fnp-3804	73	14	using	use	VERB
fnp-3804	73	15	stem	stem	NOUN
fnp-3804	73	16	cell	cell	NOUN
fnp-3804	73	17	models	model	NOUN
fnp-3804	73	18	of	of	ADP
fnp-3804	73	19	brain	brain	NOUN
fnp-3804	73	20	development	development	NOUN
fnp-3804	73	21	and	and	CCONJ
fnp-3804	73	22	gliomagenesis	gliomagenesis	NOUN
fnp-3804	73	23	.	.	PUNCT
fnp-3804	74	1	haag	haag	PROPN
fnp-3804	74	2	d	d	X
fnp-3804	74	3	et	et	PROPN
fnp-3804	74	4	al	al	PROPN
fnp-3804	74	5	.	.	PUNCT
fnp-3804	75	1	(	(	PUNCT
fnp-3804	75	2	with	with	ADP
fnp-3804	75	3	wernig	wernig	PROPN
fnp-3804	75	4	m	m	NOUN
fnp-3804	75	5	and	and	CCONJ
fnp-3804	75	6	pfister	pfister	NOUN
fnp-3804	75	7	sm	sm	INTJ
fnp-3804	75	8	as	as	ADP
fnp-3804	75	9	senior	senior	ADJ
fnp-3804	75	10	authors	author	NOUN
fnp-3804	75	11	)	)	PUNCT
fnp-3804	75	12	published	publish	VERB
fnp-3804	75	13	a	a	DET
fnp-3804	75	14	study	study	NOUN
fnp-3804	75	15	in	in	ADP
fnp-3804	75	16	cancer	cancer	NOUN
fnp-3804	75	17	cell	cell	NOUN
fnp-3804	75	18	in	in	ADP
fnp-3804	75	19	which	which	PRON
fnp-3804	75	20	they	they	PRON
fnp-3804	75	21	investigated	investigate	VERB
fnp-3804	75	22	the	the	DET
fnp-3804	75	23	effects	effect	NOUN
fnp-3804	75	24	of	of	ADP
fnp-3804	75	25	the	the	DET
fnp-3804	75	26	h3	h3	NOUN
fnp-3804	75	27	k27	k27	PROPN
fnp-3804	75	28	m	m	PROPN
fnp-3804	75	29	mutation	mutation	NOUN
fnp-3804	75	30	,	,	PUNCT
fnp-3804	75	31	which	which	PRON
fnp-3804	75	32	co	co	VERB
fnp-3804	75	33	-	-	VERB
fnp-3804	75	34	occurs	occur	VERB
fnp-3804	75	35	in	in	ADP
fnp-3804	75	36	diffuse	diffuse	ADJ
fnp-3804	75	37	midline	midline	NOUN
fnp-3804	75	38	gliomas	glioma	NOUN
fnp-3804	75	39	(	(	PUNCT
fnp-3804	75	40	dmgs	dmgs	PROPN
fnp-3804	75	41	)	)	PUNCT
fnp-3804	75	42	with	with	ADP
fnp-3804	75	43	a	a	DET
fnp-3804	75	44	mutation	mutation	NOUN
fnp-3804	75	45	in	in	ADP
fnp-3804	75	46	tp53	tp53	PROPN
fnp-3804	75	47	in	in	ADP
fnp-3804	75	48	77	77	NUM
fnp-3804	75	49	%	%	NOUN
fnp-3804	75	50	of	of	ADP
fnp-3804	75	51	cases	case	NOUN
fnp-3804	75	52	4	4	NUM
fnp-3804	75	53	.	.	PUNCT
fnp-3804	75	54	previous	previous	ADJ
fnp-3804	75	55	single	single	ADJ
fnp-3804	75	56	cell	cell	NOUN
fnp-3804	75	57	rnaseq	rnaseq	NOUN
fnp-3804	75	58	studies	study	NOUN
fnp-3804	75	59	of	of	ADP
fnp-3804	75	60	dmgs	dmgs	NOUN
fnp-3804	75	61	,	,	PUNCT
fnp-3804	75	62	h3	h3	VERB
fnp-3804	75	63	k27m	k27m	NOUN
fnp-3804	75	64	-	-	ADJ
fnp-3804	75	65	mutant	mutant	NOUN
fnp-3804	75	66	revealed	reveal	VERB
fnp-3804	75	67	that	that	SCONJ
fnp-3804	75	68	these	these	DET
fnp-3804	75	69	tumors	tumor	NOUN
fnp-3804	75	70	may	may	AUX
fnp-3804	75	71	originate	originate	VERB
fnp-3804	75	72	from	from	ADP
fnp-3804	75	73	an	an	DET
fnp-3804	75	74	oligodendrocyte	oligodendrocyte	ADJ
fnp-3804	75	75	progenitor	progenitor	NOUN
fnp-3804	75	76	cell	cell	NOUN
fnp-3804	75	77	(	(	PUNCT
fnp-3804	75	78	opc	opc	PROPN
fnp-3804	75	79	)	)	PUNCT
fnp-3804	75	80	24	24	NUM
fnp-3804	75	81	.	.	PUNCT
fnp-3804	76	1	haag	haag	PROPN
fnp-3804	76	2	et	et	PROPN
fnp-3804	76	3	al	al	PROPN
fnp-3804	76	4	.	.	PROPN
fnp-3804	76	5	inserted	insert	VERB
fnp-3804	76	6	a	a	DET
fnp-3804	76	7	k27	k27	NOUN
fnp-3804	76	8	m	m	NOUN
fnp-3804	76	9	mutation	mutation	NOUN
fnp-3804	76	10	in	in	ADP
fnp-3804	76	11	neural	neural	ADJ
fnp-3804	76	12	stem	stem	NOUN
fnp-3804	76	13	cell	cell	NOUN
fnp-3804	76	14	(	(	PUNCT
fnp-3804	76	15	nsc	nsc	PROPN
fnp-3804	76	16	)	)	PUNCT
fnp-3804	76	17	and	and	CCONJ
fnp-3804	76	18	opc	opc	PROPN
fnp-3804	76	19	lines	line	NOUN
fnp-3804	76	20	,	,	PUNCT
fnp-3804	76	21	which	which	PRON
fnp-3804	76	22	increased	increase	VERB
fnp-3804	76	23	proliferation	proliferation	NOUN
fnp-3804	76	24	in	in	ADP
fnp-3804	76	25	these	these	DET
fnp-3804	76	26	cell	cell	NOUN
fnp-3804	76	27	lines	line	NOUN
fnp-3804	76	28	.	.	PUNCT
fnp-3804	77	1	interestingly	interestingly	ADV
fnp-3804	77	2	,	,	PUNCT
fnp-3804	77	3	only	only	ADV
fnp-3804	77	4	nsc	nsc	PROPN
fnp-3804	77	5	lines	line	NOUN
fnp-3804	77	6	with	with	ADP
fnp-3804	77	7	k27	k27	PROPN
fnp-3804	77	8	m	m	PROPN
fnp-3804	77	9	and	and	CCONJ
fnp-3804	77	10	knock	knock	NOUN
fnp-3804	77	11	-	-	PUNCT
fnp-3804	77	12	out	out	NOUN
fnp-3804	77	13	of	of	ADP
fnp-3804	77	14	tp53	tp53	PROPN
fnp-3804	77	15	formed	form	VERB
fnp-3804	77	16	malignant	malignant	ADJ
fnp-3804	77	17	tumors	tumor	NOUN
fnp-3804	77	18	in	in	ADP
fnp-3804	77	19	mouse	mouse	NOUN
fnp-3804	77	20	xenografts	xenograft	NOUN
fnp-3804	77	21	that	that	PRON
fnp-3804	77	22	resembled	resemble	VERB
fnp-3804	77	23	the	the	DET
fnp-3804	77	24	pathology	pathology	NOUN
fnp-3804	77	25	of	of	ADP
fnp-3804	77	26	dmgs	dmgs	PROPN
fnp-3804	77	27	.	.	PUNCT
fnp-3804	78	1	as	as	SCONJ
fnp-3804	78	2	this	this	DET
fnp-3804	78	3	finding	finding	NOUN
fnp-3804	78	4	is	be	AUX
fnp-3804	78	5	inconsistent	inconsistent	ADJ
fnp-3804	78	6	with	with	ADP
fnp-3804	78	7	prior	prior	ADJ
fnp-3804	78	8	reports	report	NOUN
fnp-3804	78	9	of	of	ADP
fnp-3804	78	10	the	the	DET
fnp-3804	78	11	cell	cell	NOUN
fnp-3804	78	12	-	-	PUNCT
fnp-3804	78	13	of	of	ADP
fnp-3804	78	14	-	-	PUNCT
fnp-3804	78	15	origin	origin	NOUN
fnp-3804	78	16	,	,	PUNCT
fnp-3804	78	17	the	the	DET
fnp-3804	78	18	authors	author	NOUN
fnp-3804	78	19	hypothesized	hypothesize	VERB
fnp-3804	78	20	that	that	SCONJ
fnp-3804	78	21	the	the	DET
fnp-3804	78	22	k27	k27	PROPN
fnp-3804	78	23	m	m	NOUN
fnp-3804	78	24	mutation	mutation	NOUN
fnp-3804	78	25	could	could	AUX
fnp-3804	78	26	cause	cause	VERB
fnp-3804	78	27	nsc	nsc	PROPN
fnp-3804	78	28	to	to	PART
fnp-3804	78	29	adopt	adopt	VERB
fnp-3804	78	30	an	an	DET
fnp-3804	78	31	opc	opc	PROPN
fnp-3804	78	32	-	-	PUNCT
fnp-3804	78	33	like	like	ADJ
fnp-3804	78	34	transcriptional	transcriptional	NOUN
fnp-3804	78	35	profile	profile	NOUN
fnp-3804	78	36	.	.	PUNCT
fnp-3804	79	1	to	to	ADP
fnp-3804	79	2	this	this	DET
fnp-3804	79	3	end	end	NOUN
fnp-3804	79	4	,	,	PUNCT
fnp-3804	79	5	the	the	DET
fnp-3804	79	6	authors	author	NOUN
fnp-3804	79	7	used	use	VERB
fnp-3804	79	8	chromatin	chromatin	NOUN
fnp-3804	79	9	immunoprecipitation	immunoprecipitation	NOUN
fnp-3804	79	10	sequencing	sequence	VERB
fnp-3804	79	11	(	(	PUNCT
fnp-3804	79	12	chip	chip	NOUN
fnp-3804	79	13	-	-	PUNCT
fnp-3804	79	14	seq	seq	NOUN
fnp-3804	79	15	)	)	PUNCT
fnp-3804	79	16	to	to	PART
fnp-3804	79	17	describe	describe	VERB
fnp-3804	79	18	the	the	DET
fnp-3804	79	19	interactions	interaction	NOUN
fnp-3804	79	20	between	between	ADP
fnp-3804	79	21	mutant	mutant	ADJ
fnp-3804	79	22	h3.3	h3.3	NOUN
fnp-3804	79	23	and	and	CCONJ
fnp-3804	79	24	dna	dna	PROPN
fnp-3804	79	25	.	.	PUNCT
fnp-3804	80	1	they	they	PRON
fnp-3804	80	2	found	find	VERB
fnp-3804	80	3	h3.3	h3.3	NOUN
fnp-3804	80	4	enrichment	enrichment	NOUN
fnp-3804	80	5	in	in	ADP
fnp-3804	80	6	bivalent	bivalent	ADJ
fnp-3804	80	7	chromatin	chromatin	NOUN
fnp-3804	80	8	domains	domain	NOUN
fnp-3804	80	9	which	which	PRON
fnp-3804	80	10	maintains	maintain	VERB
fnp-3804	80	11	the	the	DET
fnp-3804	80	12	expression	expression	NOUN
fnp-3804	80	13	genes	gene	NOUN
fnp-3804	80	14	necessary	necessary	ADJ
fnp-3804	80	15	for	for	ADP
fnp-3804	80	16	pluripotency	pluripotency	NOUN
fnp-3804	80	17	and	and	CCONJ
fnp-3804	80	18	stem	stem	NOUN
fnp-3804	80	19	cell	cell	NOUN
fnp-3804	80	20	identity	identity	NOUN
fnp-3804	80	21	.	.	PUNCT
fnp-3804	81	1	this	this	PRON
fnp-3804	81	2	can	can	AUX
fnp-3804	81	3	explain	explain	VERB
fnp-3804	81	4	how	how	SCONJ
fnp-3804	81	5	k27m	k27m	NOUN
fnp-3804	81	6	-	-	ADJ
fnp-3804	81	7	mutant	mutant	ADJ
fnp-3804	81	8	nscs	nsc	NOUN
fnp-3804	81	9	can	can	AUX
fnp-3804	81	10	mimic	mimic	VERB
fnp-3804	81	11	opc	opc	PROPN
fnp-3804	81	12	transcriptional	transcriptional	NOUN
fnp-3804	81	13	programs	program	NOUN
fnp-3804	81	14	and	and	CCONJ
fnp-3804	81	15	could	could	AUX
fnp-3804	81	16	drive	drive	VERB
fnp-3804	81	17	these	these	DET
fnp-3804	81	18	tumors	tumor	NOUN
fnp-3804	81	19	.	.	PUNCT
fnp-3804	82	1	bressan	bressan	PROPN
fnp-3804	82	2	rb	rb	PROPN
fnp-3804	82	3	et	et	PROPN
fnp-3804	82	4	al	al	PROPN
fnp-3804	82	5	.	.	PUNCT
fnp-3804	83	1	(	(	PUNCT
fnp-3804	83	2	with	with	ADP
fnp-3804	83	3	pollard	pollard	PROPN
fnp-3804	83	4	sm	sm	PROPN
fnp-3804	83	5	as	as	ADP
fnp-3804	83	6	lead	lead	ADJ
fnp-3804	83	7	contact	contact	NOUN
fnp-3804	83	8	)	)	PUNCT
fnp-3804	83	9	described	describe	VERB
fnp-3804	83	10	the	the	DET
fnp-3804	83	11	oncogenic	oncogenic	ADJ
fnp-3804	83	12	effects	effect	NOUN
fnp-3804	83	13	of	of	ADP
fnp-3804	83	14	the	the	DET
fnp-3804	83	15	g34r	g34r	NOUN
fnp-3804	83	16	mutation	mutation	NOUN
fnp-3804	83	17	in	in	ADP
fnp-3804	83	18	nsc	nsc	PROPN
fnp-3804	83	19	lines	line	NOUN
fnp-3804	83	20	derived	derive	VERB
fnp-3804	83	21	from	from	ADP
fnp-3804	83	22	the	the	DET
fnp-3804	83	23	forebrain	forebrain	NOUN
fnp-3804	83	24	and	and	CCONJ
fnp-3804	83	25	hindbrain	hindbrain	NOUN
fnp-3804	83	26	in	in	ADP
fnp-3804	83	27	a	a	DET
fnp-3804	83	28	paper	paper	NOUN
fnp-3804	83	29	in	in	ADP
fnp-3804	83	30	cell	cell	NOUN
fnp-3804	83	31	stem	stem	NOUN
fnp-3804	83	32	cell	cell	NOUN
fnp-3804	83	33	5	5	NUM
fnp-3804	83	34	.	.	PUNCT
fnp-3804	84	1	forebrain	forebrain	NOUN
fnp-3804	84	2	nsc	nsc	PROPN
fnp-3804	84	3	lines	line	NOUN
fnp-3804	84	4	with	with	ADP
fnp-3804	84	5	only	only	ADV
fnp-3804	84	6	the	the	DET
fnp-3804	84	7	g34r	g34r	NOUN
fnp-3804	84	8	mutation	mutation	NOUN
fnp-3804	84	9	had	have	VERB
fnp-3804	84	10	low	low	ADJ
fnp-3804	84	11	tumorigenic	tumorigenic	ADJ
fnp-3804	84	12	capacities	capacity	NOUN
fnp-3804	84	13	.	.	PUNCT
fnp-3804	85	1	however	however	ADV
fnp-3804	85	2	,	,	PUNCT
fnp-3804	85	3	combination	combination	NOUN
fnp-3804	85	4	of	of	ADP
fnp-3804	85	5	knockout	knockout	NOUN
fnp-3804	85	6	of	of	ADP
fnp-3804	85	7	tp53	tp53	PROPN
fnp-3804	85	8	and	and	CCONJ
fnp-3804	85	9	amplification	amplification	NOUN
fnp-3804	85	10	of	of	ADP
fnp-3804	85	11	pdgfra	pdgfra	NOUN
fnp-3804	85	12	in	in	ADP
fnp-3804	85	13	these	these	DET
fnp-3804	85	14	cells	cell	NOUN
fnp-3804	85	15	resulted	result	VERB
fnp-3804	85	16	in	in	ADP
fnp-3804	85	17	increased	increase	VERB
fnp-3804	85	18	proliferation	proliferation	NOUN
fnp-3804	85	19	and	and	CCONJ
fnp-3804	85	20	the	the	DET
fnp-3804	85	21	formation	formation	NOUN
fnp-3804	85	22	of	of	ADP
fnp-3804	85	23	malignant	malignant	ADJ
fnp-3804	85	24	tumors	tumor	NOUN
fnp-3804	85	25	when	when	SCONJ
fnp-3804	85	26	xenografted	xenografte	VERB
fnp-3804	85	27	in	in	ADP
fnp-3804	85	28	mice	mouse	NOUN
fnp-3804	85	29	.	.	PUNCT
fnp-3804	86	1	the	the	DET
fnp-3804	86	2	authors	author	NOUN
fnp-3804	86	3	then	then	ADV
fnp-3804	86	4	sought	seek	VERB
fnp-3804	86	5	to	to	PART
fnp-3804	86	6	describe	describe	VERB
fnp-3804	86	7	the	the	DET
fnp-3804	86	8	epigenetic	epigenetic	ADJ
fnp-3804	86	9	effects	effect	NOUN
fnp-3804	86	10	of	of	ADP
fnp-3804	86	11	the	the	DET
fnp-3804	86	12	h3	h3	NOUN
fnp-3804	86	13	g34r	g34r	NOUN
fnp-3804	86	14	mutation	mutation	NOUN
fnp-3804	86	15	.	.	PUNCT
fnp-3804	87	1	unlike	unlike	ADP
fnp-3804	87	2	the	the	DET
fnp-3804	87	3	k27	k27	PROPN
fnp-3804	87	4	m	m	PROPN
fnp-3804	87	5	mutation	mutation	NOUN
fnp-3804	87	6	,	,	PUNCT
fnp-3804	87	7	which	which	PRON
fnp-3804	87	8	causes	cause	VERB
fnp-3804	87	9	wide	wide	ADV
fnp-3804	87	10	-	-	PUNCT
fnp-3804	87	11	spread	spread	VERB
fnp-3804	87	12	epigenetic	epigenetic	ADJ
fnp-3804	87	13	and	and	CCONJ
fnp-3804	87	14	transcriptional	transcriptional	ADJ
fnp-3804	87	15	changes	change	NOUN
fnp-3804	87	16	,	,	PUNCT
fnp-3804	87	17	the	the	DET
fnp-3804	87	18	authors	author	NOUN
fnp-3804	87	19	found	find	VERB
fnp-3804	87	20	that	that	SCONJ
fnp-3804	87	21	the	the	DET
fnp-3804	87	22	g34r	g34r	NOUN
fnp-3804	87	23	mutation	mutation	NOUN
fnp-3804	87	24	reduces	reduce	VERB
fnp-3804	87	25	binding	bind	VERB
fnp-3804	87	26	with	with	ADP
fnp-3804	87	27	zmynd11	zmynd11	PROPN
fnp-3804	87	28	,	,	PUNCT
fnp-3804	87	29	a	a	DET
fnp-3804	87	30	tumor	tumor	NOUN
fnp-3804	87	31	suppressor	suppressor	NOUN
fnp-3804	87	32	that	that	PRON
fnp-3804	87	33	alters	alter	VERB
fnp-3804	87	34	the	the	DET
fnp-3804	87	35	elongation	elongation	NOUN
fnp-3804	87	36	and	and	CCONJ
fnp-3804	87	37	splicing	splicing	NOUN
fnp-3804	87	38	of	of	ADP
fnp-3804	87	39	highly	highly	ADV
fnp-3804	87	40	expressed	express	VERB
fnp-3804	87	41	genes	gene	NOUN
fnp-3804	87	42	.	.	PUNCT
fnp-3804	88	1	in	in	ADP
fnp-3804	88	2	the	the	DET
fnp-3804	88	3	context	context	NOUN
fnp-3804	88	4	of	of	ADP
fnp-3804	88	5	brain	brain	NOUN
fnp-3804	88	6	tumors	tumor	NOUN
fnp-3804	88	7	,	,	PUNCT
fnp-3804	88	8	this	this	PRON
fnp-3804	88	9	results	result	VERB
fnp-3804	88	10	in	in	ADP
fnp-3804	88	11	higher	high	ADJ
fnp-3804	88	12	expression	expression	NOUN
fnp-3804	88	13	of	of	ADP
fnp-3804	88	14	genes	gene	NOUN
fnp-3804	88	15	that	that	PRON
fnp-3804	88	16	regulate	regulate	VERB
fnp-3804	88	17	forebrain	forebrain	NOUN
fnp-3804	88	18	development	development	NOUN
fnp-3804	88	19	and	and	CCONJ
fnp-3804	88	20	locks	lock	NOUN
fnp-3804	88	21	nscs	nsc	VERB
fnp-3804	88	22	into	into	ADP
fnp-3804	88	23	a	a	DET
fnp-3804	88	24	proliferative	proliferative	ADJ
fnp-3804	88	25	and	and	CCONJ
fnp-3804	88	26	non	non	ADJ
fnp-3804	88	27	-	-	ADJ
fnp-3804	88	28	differentiated	differentiated	ADJ
fnp-3804	88	29	state	state	NOUN
fnp-3804	88	30	.	.	PUNCT
fnp-3804	89	1	together	together	ADV
fnp-3804	89	2	,	,	PUNCT
fnp-3804	89	3	these	these	DET
fnp-3804	89	4	papers	paper	NOUN
fnp-3804	89	5	very	very	ADV
fnp-3804	89	6	nicely	nicely	ADV
fnp-3804	89	7	show	show	VERB
fnp-3804	89	8	how	how	SCONJ
fnp-3804	89	9	pre	pre	ADJ
fnp-3804	89	10	-	-	ADJ
fnp-3804	89	11	clinical	clinical	ADJ
fnp-3804	89	12	stem	stem	NOUN
fnp-3804	89	13	cell	cell	NOUN
fnp-3804	89	14	modeling	modeling	NOUN
fnp-3804	89	15	can	can	AUX
fnp-3804	89	16	untangle	untangle	VERB
fnp-3804	89	17	the	the	DET
fnp-3804	89	18	mechanisms	mechanism	NOUN
fnp-3804	89	19	of	of	ADP
fnp-3804	89	20	cancer	cancer	NOUN
fnp-3804	89	21	initiation	initiation	NOUN
fnp-3804	89	22	in	in	ADP
fnp-3804	89	23	general	general	ADJ
fnp-3804	89	24	,	,	PUNCT
fnp-3804	89	25	and	and	CCONJ
fnp-3804	89	26	of	of	ADP
fnp-3804	89	27	the	the	DET
fnp-3804	89	28	oncogenesis	oncogenesis	NOUN
fnp-3804	89	29	of	of	ADP
fnp-3804	89	30	h3.3	h3.3	NOUN
fnp-3804	89	31	mutant	mutant	ADJ
fnp-3804	89	32	tumors	tumor	NOUN
fnp-3804	89	33	in	in	ADP
fnp-3804	89	34	particular	particular	ADJ
fnp-3804	89	35	.	.	PUNCT
fnp-3804	90	1	topic	topic	NOUN
fnp-3804	90	2	5	5	NUM
fnp-3804	90	3	:	:	PUNCT
fnp-3804	90	4	epigenomic	epigenomic	ADJ
fnp-3804	90	5	insights	insight	NOUN
fnp-3804	90	6	into	into	ADP
fnp-3804	90	7	glioma	glioma	NOUN
fnp-3804	90	8	cell	cell	NOUN
fnp-3804	90	9	differentiation	differentiation	NOUN
fnp-3804	90	10	and	and	CCONJ
fnp-3804	90	11	plasticity	plasticity	NOUN
fnp-3804	90	12	6,7	6,7	NUM
fnp-3804	90	13	single	single	ADJ
fnp-3804	90	14	-	-	PUNCT
fnp-3804	90	15	cell	cell	NOUN
fnp-3804	90	16	(	(	PUNCT
fnp-3804	90	17	sc	sc	NOUN
fnp-3804	90	18	)	)	PUNCT
fnp-3804	90	19	rnaseq	rnaseq	NOUN
fnp-3804	90	20	studies	study	NOUN
fnp-3804	90	21	of	of	ADP
fnp-3804	90	22	diffuse	diffuse	PROPN
fnp-3804	90	23	gliomas	glioma	NOUN
fnp-3804	90	24	have	have	AUX
fnp-3804	90	25	revealed	reveal	VERB
fnp-3804	90	26	unprecedented	unprecedented	ADJ
fnp-3804	90	27	insights	insight	NOUN
fnp-3804	90	28	into	into	ADP
fnp-3804	90	29	their	their	PRON
fnp-3804	90	30	intra	intra	ADJ
fnp-3804	90	31	-	-	ADJ
fnp-3804	90	32	tumoral	tumoral	ADJ
fnp-3804	90	33	heterogeneity	heterogeneity	NOUN
fnp-3804	90	34	,	,	PUNCT
fnp-3804	90	35	wherein	wherein	ADJ
fnp-3804	90	36	glioma	glioma	NOUN
fnp-3804	90	37	cells	cell	NOUN
fnp-3804	90	38	from	from	ADP
fnp-3804	90	39	the	the	DET
fnp-3804	90	40	same	same	ADJ
fnp-3804	90	41	tumor	tumor	NOUN
fnp-3804	90	42	exist	exist	VERB
fnp-3804	90	43	in	in	ADP
fnp-3804	90	44	different	different	ADJ
fnp-3804	90	45	transcriptionally	transcriptionally	ADV
fnp-3804	90	46	defined	define	VERB
fnp-3804	90	47	cell	cell	NOUN
fnp-3804	90	48	states	state	VERB
fnp-3804	90	49	25	25	NUM
fnp-3804	90	50	-	-	SYM
fnp-3804	90	51	27	27	NUM
fnp-3804	90	52	.	.	PUNCT
fnp-3804	91	1	many	many	ADJ
fnp-3804	91	2	of	of	ADP
fnp-3804	91	3	these	these	DET
fnp-3804	91	4	cell	cell	NOUN
fnp-3804	91	5	states	state	NOUN
fnp-3804	91	6	mirror	mirror	VERB
fnp-3804	91	7	the	the	DET
fnp-3804	91	8	neurodevelopmental	neurodevelopmental	ADJ
fnp-3804	91	9	hierarchy	hierarchy	NOUN
fnp-3804	91	10	,	,	PUNCT
fnp-3804	91	11	and	and	CCONJ
fnp-3804	91	12	it	it	PRON
fnp-3804	91	13	has	have	AUX
fnp-3804	91	14	been	be	AUX
fnp-3804	91	15	suggested	suggest	VERB
fnp-3804	91	16	that	that	SCONJ
fnp-3804	91	17	tumor	tumor	NOUN
fnp-3804	91	18	cells	cell	NOUN
fnp-3804	91	19	can	can	AUX
fnp-3804	91	20	transition	transition	VERB
fnp-3804	91	21	between	between	ADP
fnp-3804	91	22	more	more	ADV
fnp-3804	91	23	or	or	CCONJ
fnp-3804	91	24	less	less	ADV
fnp-3804	91	25	differentiated	differentiated	ADJ
fnp-3804	91	26	states	state	NOUN
fnp-3804	91	27	.	.	PUNCT
fnp-3804	92	1	such	such	DET
fnp-3804	92	2	a	a	DET
fnp-3804	92	3	plasticity	plasticity	NOUN
fnp-3804	92	4	may	may	AUX
fnp-3804	92	5	well	well	ADV
fnp-3804	92	6	contribute	contribute	VERB
fnp-3804	92	7	to	to	ADP
fnp-3804	92	8	resistance	resistance	NOUN
fnp-3804	92	9	to	to	ADP
fnp-3804	92	10	therapy	therapy	NOUN
fnp-3804	92	11	.	.	PUNCT
fnp-3804	93	1	as	as	SCONJ
fnp-3804	93	2	gene	gene	NOUN
fnp-3804	93	3	regulation	regulation	NOUN
fnp-3804	93	4	and	and	CCONJ
fnp-3804	93	5	dna	dna	PROPN
fnp-3804	93	6	methylation	methylation	NOUN
fnp-3804	93	7	(	(	PUNCT
fnp-3804	93	8	dname	dname	PROPN
fnp-3804	93	9	)	)	PUNCT
fnp-3804	93	10	can	can	AUX
fnp-3804	93	11	largely	largely	ADV
fnp-3804	93	12	control	control	VERB
fnp-3804	93	13	these	these	DET
fnp-3804	93	14	cell	cell	NOUN
fnp-3804	93	15	states	state	NOUN
fnp-3804	93	16	,	,	PUNCT
fnp-3804	93	17	back	back	NOUN
fnp-3804	93	18	-	-	PUNCT
fnp-3804	93	19	to	to	ADP
fnp-3804	93	20	-	-	PUNCT
fnp-3804	93	21	back	back	ADP
fnp-3804	93	22	papers	paper	NOUN
fnp-3804	93	23	published	publish	VERB
fnp-3804	93	24	in	in	ADP
fnp-3804	93	25	nature	nature	NOUN
fnp-3804	93	26	genetics	genetic	NOUN
fnp-3804	93	27	by	by	ADP
fnp-3804	93	28	johnson	johnson	PROPN
fnp-3804	93	29	kc	kc	PROPN
fnp-3804	93	30	and	and	CCONJ
fnp-3804	93	31	anderson	anderson	PROPN
fnp-3804	93	32	kj	kj	PROPN
fnp-3804	93	33	et	et	PROPN
fnp-3804	93	34	al	al	PROPN
fnp-3804	93	35	.	.	PROPN
fnp-3804	94	1	(	(	PUNCT
fnp-3804	94	2	with	with	ADP
fnp-3804	94	3	verhaak	verhaak	NOUN
fnp-3804	94	4	rgw	rgw	NOUN
fnp-3804	94	5	as	as	ADP
fnp-3804	94	6	senior	senior	ADJ
fnp-3804	94	7	author	author	NOUN
fnp-3804	94	8	)	)	PUNCT
fnp-3804	94	9	6	6	NUM
fnp-3804	94	10	and	and	CCONJ
fnp-3804	94	11	chaligne	chaligne	VERB
fnp-3804	94	12	r	r	NOUN
fnp-3804	94	13	,	,	PUNCT
fnp-3804	94	14	gaiti	gaiti	NOUN
fnp-3804	94	15	f	f	PROPN
fnp-3804	94	16	,	,	PUNCT
fnp-3804	94	17	silverbush	silverbush	NOUN
fnp-3804	94	18	d	d	NOUN
fnp-3804	94	19	,	,	PUNCT
fnp-3804	94	20	and	and	CCONJ
fnp-3804	94	21	schiffman	schiffman	NOUN
fnp-3804	94	22	js	js	INTJ
fnp-3804	94	23	et	et	PROPN
fnp-3804	94	24	al	al	PROPN
fnp-3804	94	25	.	.	PROPN
fnp-3804	95	1	(	(	PUNCT
fnp-3804	95	2	supervised	supervise	VERB
fnp-3804	95	3	by	by	ADP
fnp-3804	95	4	suvá	suvá	NOUN
fnp-3804	95	5	ml	ml	NOUN
fnp-3804	95	6	and	and	CCONJ
fnp-3804	95	7	landau	landau	NOUN
fnp-3804	95	8	da	da	PROPN
fnp-3804	95	9	)	)	PUNCT
fnp-3804	95	10	7	7	NUM
fnp-3804	95	11	measured	measure	VERB
fnp-3804	95	12	dname	dname	NOUN
fnp-3804	95	13	and	and	CCONJ
fnp-3804	95	14	rna	rna	NOUN
fnp-3804	95	15	expression	expression	NOUN
fnp-3804	95	16	at	at	ADP
fnp-3804	95	17	the	the	DET
fnp-3804	95	18	single	single	ADJ
fnp-3804	95	19	-	-	PUNCT
fnp-3804	95	20	cell	cell	NOUN
fnp-3804	95	21	level	level	NOUN
fnp-3804	95	22	of	of	ADP
fnp-3804	95	23	idh	idh	NOUN
fnp-3804	95	24	-	-	PUNCT
fnp-3804	95	25	wildtype	wildtype	NOUN
fnp-3804	95	26	glioblastomas	glioblastoma	NOUN
fnp-3804	95	27	in	in	ADP
fnp-3804	95	28	adults	adult	NOUN
fnp-3804	95	29	(	(	PUNCT
fnp-3804	95	30	idh	idh	NOUN
fnp-3804	95	31	-	-	PUNCT
fnp-3804	95	32	wt	wt	NOUN
fnp-3804	95	33	gbms	gbms	NOUN
fnp-3804	95	34	)	)	PUNCT
fnp-3804	95	35	and	and	CCONJ
fnp-3804	95	36	in	in	ADP
fnp-3804	95	37	idh	idh	NOUN
fnp-3804	95	38	-	-	PUNCT
fnp-3804	95	39	mutant	mutant	NOUN
fnp-3804	95	40	(	(	PUNCT
fnp-3804	95	41	idh	idh	PROPN
fnp-3804	95	42	-	-	PUNCT
fnp-3804	95	43	mt	mt	PROPN
fnp-3804	95	44	)	)	PUNCT
fnp-3804	95	45	diffuse	diffuse	PROPN
fnp-3804	95	46	gliomas	glioma	NOUN
fnp-3804	95	47	.	.	PUNCT
fnp-3804	96	1	using	use	VERB
fnp-3804	96	2	scdname	scdname	NOUN
fnp-3804	96	3	,	,	PUNCT
fnp-3804	96	4	both	both	DET
fnp-3804	96	5	articles	article	NOUN
fnp-3804	96	6	report	report	VERB
fnp-3804	96	7	on	on	ADP
fnp-3804	96	8	how	how	SCONJ
fnp-3804	96	9	glioma	glioma	ADJ
fnp-3804	96	10	cells	cell	NOUN
fnp-3804	96	11	from	from	ADP
fnp-3804	96	12	the	the	DET
fnp-3804	96	13	same	same	ADJ
fnp-3804	96	14	patient	patient	NOUN
fnp-3804	96	15	exist	exist	VERB
fnp-3804	96	16	in	in	ADP
fnp-3804	96	17	different	different	ADJ
fnp-3804	96	18	methylation	methylation	NOUN
fnp-3804	96	19	states	state	NOUN
fnp-3804	96	20	,	,	PUNCT
fnp-3804	96	21	while	while	SCONJ
fnp-3804	96	22	cells	cell	NOUN
fnp-3804	96	23	from	from	ADP
fnp-3804	96	24	different	different	ADJ
fnp-3804	96	25	patients	patient	NOUN
fnp-3804	96	26	can	can	AUX
fnp-3804	96	27	exist	exist	VERB
fnp-3804	96	28	in	in	ADP
fnp-3804	96	29	the	the	DET
fnp-3804	96	30	same	same	ADJ
fnp-3804	96	31	states	state	NOUN
fnp-3804	96	32	.	.	PUNCT
fnp-3804	97	1	these	these	DET
fnp-3804	97	2	studies	study	NOUN
fnp-3804	97	3	re	re	NOUN
fnp-3804	97	4	-	-	NOUN
fnp-3804	97	5	affirm	affirm	ADJ
fnp-3804	97	6	that	that	PRON
fnp-3804	97	7	diffuse	diffuse	VERB
fnp-3804	97	8	gliomas	glioma	NOUN
fnp-3804	97	9	,	,	PUNCT
fnp-3804	97	10	especially	especially	ADV
fnp-3804	97	11	gbms	gbms	NOUN
fnp-3804	97	12	,	,	PUNCT
fnp-3804	97	13	have	have	VERB
fnp-3804	97	14	high	high	ADJ
fnp-3804	97	15	intra	intra	ADJ
fnp-3804	97	16	-	-	ADJ
fnp-3804	97	17	tumoral	tumoral	ADJ
fnp-3804	97	18	heterogeneity	heterogeneity	NOUN
fnp-3804	97	19	,	,	PUNCT
fnp-3804	97	20	with	with	ADP
fnp-3804	97	21	malignant	malignant	ADJ
fnp-3804	97	22	cells	cell	NOUN
fnp-3804	97	23	adopting	adopt	VERB
fnp-3804	97	24	different	different	ADJ
fnp-3804	97	25	epigenotypes	epigenotype	NOUN
fnp-3804	97	26	.	.	PUNCT
fnp-3804	98	1	obviously	obviously	ADV
fnp-3804	98	2	,	,	PUNCT
fnp-3804	98	3	the	the	DET
fnp-3804	98	4	bulk	bulk	ADJ
fnp-3804	98	5	methylation	methylation	NOUN
fnp-3804	98	6	assays	assay	NOUN
fnp-3804	98	7	that	that	PRON
fnp-3804	98	8	are	be	AUX
fnp-3804	98	9	frequently	frequently	ADV
fnp-3804	98	10	used	use	VERB
fnp-3804	98	11	to	to	PART
fnp-3804	98	12	classify	classify	VERB
fnp-3804	98	13	(	(	PUNCT
fnp-3804	98	14	glial	glial	ADJ
fnp-3804	98	15	)	)	PUNCT
fnp-3804	98	16	brain	brain	NOUN
fnp-3804	98	17	tumors	tumor	NOUN
fnp-3804	98	18	fail	fail	VERB
fnp-3804	98	19	to	to	PART
fnp-3804	98	20	account	account	VERB
fnp-3804	98	21	for	for	ADP
fnp-3804	98	22	this	this	DET
fnp-3804	98	23	level	level	NOUN
fnp-3804	98	24	of	of	ADP
fnp-3804	98	25	intra	intra	ADJ
fnp-3804	98	26	-	-	ADJ
fnp-3804	98	27	tumoral	tumoral	ADJ
fnp-3804	98	28	heterogeneity	heterogeneity	NOUN
fnp-3804	98	29	that	that	PRON
fnp-3804	98	30	is	be	AUX
fnp-3804	98	31	uncovered	uncover	VERB
fnp-3804	98	32	by	by	ADP
fnp-3804	98	33	such	such	ADJ
fnp-3804	98	34	single	single	ADJ
fnp-3804	98	35	-	-	PUNCT
fnp-3804	98	36	cell	cell	NOUN
fnp-3804	98	37	analyses	analysis	NOUN
fnp-3804	98	38	.	.	PUNCT
fnp-3804	99	1	both	both	DET
fnp-3804	99	2	articles	article	NOUN
fnp-3804	99	3	took	take	VERB
fnp-3804	99	4	different	different	ADJ
fnp-3804	99	5	approaches	approach	NOUN
fnp-3804	99	6	to	to	PART
fnp-3804	99	7	describe	describe	VERB
fnp-3804	99	8	the	the	DET
fnp-3804	99	9	epigenomic	epigenomic	ADJ
fnp-3804	99	10	landscape	landscape	NOUN
fnp-3804	99	11	that	that	PRON
fnp-3804	99	12	gives	give	VERB
fnp-3804	99	13	rise	rise	NOUN
fnp-3804	99	14	to	to	ADP
fnp-3804	99	15	the	the	DET
fnp-3804	99	16	differentiation	differentiation	NOUN
fnp-3804	99	17	hierarchies	hierarchy	NOUN
fnp-3804	99	18	in	in	ADP
fnp-3804	99	19	gliomas	glioma	NOUN
fnp-3804	99	20	.	.	PUNCT
fnp-3804	100	1	chaligne	chaligne	VERB
fnp-3804	100	2	et	et	PROPN
fnp-3804	100	3	al	al	PROPN
fnp-3804	100	4	.	.	PROPN
fnp-3804	100	5	report	report	VERB
fnp-3804	100	6	that	that	SCONJ
fnp-3804	100	7	,	,	PUNCT
fnp-3804	100	8	compared	compare	VERB
fnp-3804	100	9	to	to	ADP
fnp-3804	100	10	idh	idh	PROPN
fnp-3804	100	11	-	-	PUNCT
fnp-3804	100	12	mt	mt	NOUN
fnp-3804	100	13	gliomas	glioma	NOUN
fnp-3804	100	14	,	,	PUNCT
fnp-3804	100	15	polycomb	polycomb	NOUN
fnp-3804	100	16	complexes	complex	NOUN
fnp-3804	100	17	in	in	ADP
fnp-3804	100	18	idh	idh	NOUN
fnp-3804	100	19	-	-	PUNCT
fnp-3804	100	20	wt	wt	NOUN
fnp-3804	100	21	gbms	gbms	NOUN
fnp-3804	100	22	are	be	AUX
fnp-3804	100	23	more	more	ADV
fnp-3804	100	24	hypermethylated	hypermethylate	VERB
fnp-3804	100	25	in	in	ADP
fnp-3804	100	26	stem	stem	NOUN
fnp-3804	100	27	-	-	PUNCT
fnp-3804	100	28	like	like	ADJ
fnp-3804	100	29	cells	cell	NOUN
fnp-3804	100	30	than	than	ADP
fnp-3804	100	31	in	in	ADP
fnp-3804	100	32	differentiated	differentiated	ADJ
fnp-3804	100	33	cells	cell	NOUN
fnp-3804	100	34	.	.	PUNCT
fnp-3804	101	1	this	this	PRON
fnp-3804	101	2	suggests	suggest	VERB
fnp-3804	101	3	a	a	DET
fnp-3804	101	4	role	role	NOUN
fnp-3804	101	5	for	for	ADP
fnp-3804	101	6	dname	dname	NOUN
fnp-3804	101	7	in	in	ADP
fnp-3804	101	8	maintaining	maintain	VERB
fnp-3804	101	9	a	a	DET
fnp-3804	101	10	stem	stem	NOUN
fnp-3804	101	11	-	-	PUNCT
fnp-3804	101	12	like	like	ADJ
fnp-3804	101	13	phenotype	phenotype	NOUN
fnp-3804	101	14	of	of	ADP
fnp-3804	101	15	gbm	gbm	NOUN
fnp-3804	101	16	cells	cell	NOUN
fnp-3804	101	17	,	,	PUNCT
fnp-3804	101	18	thereby	thereby	ADV
fnp-3804	101	19	contributing	contribute	VERB
fnp-3804	101	20	to	to	ADP
fnp-3804	101	21	their	their	PRON
fnp-3804	101	22	treatment	treatment	NOUN
fnp-3804	101	23	resistance	resistance	NOUN
fnp-3804	101	24	and	and	CCONJ
fnp-3804	101	25	progression	progression	NOUN
fnp-3804	101	26	.	.	PUNCT
fnp-3804	102	1	however	however	ADV
fnp-3804	102	2	,	,	PUNCT
fnp-3804	102	3	this	this	PRON
fnp-3804	102	4	was	be	AUX
fnp-3804	102	5	not	not	PART
fnp-3804	102	6	seen	see	VERB
fnp-3804	102	7	in	in	ADP
fnp-3804	102	8	idh	idh	PROPN
fnp-3804	102	9	-	-	PUNCT
fnp-3804	102	10	mt	mt	NOUN
fnp-3804	102	11	gliomas	glioma	NOUN
fnp-3804	102	12	,	,	PUNCT
fnp-3804	102	13	suggesting	suggest	VERB
fnp-3804	102	14	a	a	DET
fnp-3804	102	15	different	different	ADJ
fnp-3804	102	16	role	role	NOUN
fnp-3804	102	17	of	of	ADP
fnp-3804	102	18	dname	dname	NOUN
fnp-3804	102	19	in	in	ADP
fnp-3804	102	20	maintaining	maintain	VERB
fnp-3804	102	21	their	their	PRON
fnp-3804	102	22	stem	stem	NOUN
fnp-3804	102	23	-	-	PUNCT
fnp-3804	102	24	like	like	ADJ
fnp-3804	102	25	cell	cell	NOUN
fnp-3804	102	26	states	state	NOUN
fnp-3804	102	27	.	.	PUNCT
fnp-3804	103	1	furthermore	furthermore	ADV
fnp-3804	103	2	,	,	PUNCT
fnp-3804	103	3	the	the	DET
fnp-3804	103	4	authors	author	NOUN
fnp-3804	103	5	constructed	construct	VERB
fnp-3804	103	6	lineage	lineage	NOUN
fnp-3804	103	7	trees	tree	NOUN
fnp-3804	103	8	using	use	VERB
fnp-3804	103	9	scdname	scdname	NOUN
fnp-3804	103	10	and	and	CCONJ
fnp-3804	103	11	found	find	VERB
fnp-3804	103	12	that	that	SCONJ
fnp-3804	103	13	cells	cell	NOUN
fnp-3804	103	14	within	within	ADP
fnp-3804	103	15	each	each	DET
fnp-3804	103	16	clade	clade	NOUN
fnp-3804	103	17	had	have	VERB
fnp-3804	103	18	the	the	DET
fnp-3804	103	19	same	same	ADJ
fnp-3804	103	20	chromosomal	chromosomal	ADJ
fnp-3804	103	21	aberrations	aberration	NOUN
fnp-3804	103	22	.	.	PUNCT
fnp-3804	104	1	this	this	DET
fnp-3804	104	2	highlights	highlight	VERB
fnp-3804	104	3	how	how	SCONJ
fnp-3804	104	4	sub	sub	ADJ
fnp-3804	104	5	-	-	ADJ
fnp-3804	104	6	clonal	clonal	ADJ
fnp-3804	104	7	mutations	mutation	NOUN
fnp-3804	104	8	are	be	AUX
fnp-3804	104	9	related	relate	VERB
fnp-3804	104	10	with	with	ADP
fnp-3804	104	11	the	the	DET
fnp-3804	104	12	epigenotype	epigenotype	NOUN
fnp-3804	104	13	of	of	ADP
fnp-3804	104	14	glioma	glioma	NOUN
fnp-3804	104	15	cells	cell	NOUN
fnp-3804	104	16	.	.	PUNCT
fnp-3804	105	1	interestingly	interestingly	ADV
fnp-3804	105	2	,	,	PUNCT
fnp-3804	105	3	when	when	SCONJ
fnp-3804	105	4	the	the	DET
fnp-3804	105	5	authors	author	NOUN
fnp-3804	105	6	inferred	infer	VERB
fnp-3804	105	7	glioma	glioma	NOUN
fnp-3804	105	8	cell	cell	NOUN
fnp-3804	105	9	state	state	NOUN
fnp-3804	105	10	(	(	PUNCT
fnp-3804	105	11	npc	npc	PROPN
fnp-3804	105	12	,	,	PUNCT
fnp-3804	105	13	opc	opc	PROPN
fnp-3804	105	14	,	,	PUNCT
fnp-3804	105	15	ac	ac	PROPN
fnp-3804	105	16	,	,	PUNCT
fnp-3804	105	17	mes	me	NOUN
fnp-3804	105	18	)	)	PUNCT
fnp-3804	105	19	based	base	VERB
fnp-3804	105	20	on	on	ADP
fnp-3804	105	21	scrnaseq	scrnaseq	NOUN
fnp-3804	105	22	for	for	ADP
fnp-3804	105	23	idh	idh	NOUN
fnp-3804	105	24	-	-	PUNCT
fnp-3804	105	25	wt	wt	NOUN
fnp-3804	105	26	gbms	gbms	NOUN
fnp-3804	105	27	,	,	PUNCT
fnp-3804	105	28	they	they	PRON
fnp-3804	105	29	found	find	VERB
fnp-3804	105	30	that	that	SCONJ
fnp-3804	105	31	cells	cell	NOUN
fnp-3804	105	32	within	within	ADP
fnp-3804	105	33	the	the	DET
fnp-3804	105	34	same	same	ADJ
fnp-3804	105	35	lineage	lineage	NOUN
fnp-3804	105	36	adopted	adopt	VERB
fnp-3804	105	37	different	different	ADJ
fnp-3804	105	38	transcriptional	transcriptional	ADJ
fnp-3804	105	39	states	state	NOUN
fnp-3804	105	40	.	.	PUNCT
fnp-3804	106	1	however	however	ADV
fnp-3804	106	2	,	,	PUNCT
fnp-3804	106	3	the	the	DET
fnp-3804	106	4	reverse	reverse	NOUN
fnp-3804	106	5	was	be	AUX
fnp-3804	106	6	found	find	VERB
fnp-3804	106	7	for	for	ADP
fnp-3804	106	8	idh	idh	PROPN
fnp-3804	106	9	-	-	PUNCT
fnp-3804	106	10	mt	mt	NOUN
fnp-3804	106	11	glioma	glioma	NOUN
fnp-3804	106	12	,	,	PUNCT
fnp-3804	106	13	where	where	SCONJ
fnp-3804	106	14	closely	closely	ADV
fnp-3804	106	15	related	related	ADJ
fnp-3804	106	16	cells	cell	NOUN
fnp-3804	106	17	obtained	obtain	VERB
fnp-3804	106	18	similar	similar	ADJ
fnp-3804	106	19	cell	cell	NOUN
fnp-3804	106	20	states	state	NOUN
fnp-3804	106	21	.	.	PUNCT
fnp-3804	107	1	altogether	altogether	ADV
fnp-3804	107	2	,	,	PUNCT
fnp-3804	107	3	these	these	DET
fnp-3804	107	4	results	result	NOUN
fnp-3804	107	5	confirm	confirm	VERB
fnp-3804	107	6	that	that	SCONJ
fnp-3804	107	7	idh	idh	NOUN
fnp-3804	107	8	-	-	PUNCT
fnp-3804	107	9	wt	wt	NOUN
fnp-3804	107	10	gbms	gbms	NOUN
fnp-3804	107	11	have	have	VERB
fnp-3804	107	12	higher	high	ADJ
fnp-3804	107	13	cell	cell	NOUN
fnp-3804	107	14	plasticity	plasticity	NOUN
fnp-3804	107	15	than	than	ADP
fnp-3804	107	16	idh	idh	NOUN
fnp-3804	107	17	-	-	PUNCT
fnp-3804	107	18	mt	mt	NOUN
fnp-3804	107	19	glioma	glioma	NOUN
fnp-3804	107	20	,	,	PUNCT
fnp-3804	107	21	and	and	CCONJ
fnp-3804	107	22	dname	dname	NOUN
fnp-3804	107	23	contributes	contribute	VERB
fnp-3804	107	24	to	to	ADP
fnp-3804	107	25	the	the	DET
fnp-3804	107	26	glioma	glioma	NOUN
fnp-3804	107	27	stem	stem	NOUN
fnp-3804	107	28	-	-	PUNCT
fnp-3804	107	29	like	like	ADJ
fnp-3804	107	30	identity	identity	NOUN
fnp-3804	107	31	.	.	PUNCT
fnp-3804	108	1	johnson	johnson	PROPN
fnp-3804	108	2	et	et	PROPN
fnp-3804	108	3	al	al	PROPN
fnp-3804	108	4	.	.	PROPN
fnp-3804	108	5	also	also	ADV
fnp-3804	108	6	investigated	investigate	VERB
fnp-3804	108	7	the	the	DET
fnp-3804	108	8	contribution	contribution	NOUN
fnp-3804	108	9	of	of	ADP
fnp-3804	108	10	‘	'	PUNCT
fnp-3804	108	11	dname	dname	NOUN
fnp-3804	108	12	disorder	disorder	NOUN
fnp-3804	108	13	’	'	PUNCT
fnp-3804	108	14	(	(	PUNCT
fnp-3804	108	15	i.e.	i.e.	X
fnp-3804	108	16	,	,	PUNCT
fnp-3804	108	17	aberrant	aberrant	ADJ
fnp-3804	108	18	methylation	methylation	NOUN
fnp-3804	108	19	which	which	PRON
fnp-3804	108	20	allows	allow	VERB
fnp-3804	108	21	cells	cell	NOUN
fnp-3804	108	22	to	to	PART
fnp-3804	108	23	adapt	adapt	VERB
fnp-3804	108	24	to	to	ADP
fnp-3804	108	25	diverse	diverse	ADJ
fnp-3804	108	26	methylation	methylation	NOUN
fnp-3804	108	27	states	state	NOUN
fnp-3804	108	28	)	)	PUNCT
fnp-3804	108	29	for	for	ADP
fnp-3804	108	30	maintaining	maintain	VERB
fnp-3804	108	31	the	the	DET
fnp-3804	108	32	stem	stem	NOUN
fnp-3804	108	33	-	-	PUNCT
fnp-3804	108	34	like	like	ADJ
fnp-3804	108	35	identity	identity	NOUN
fnp-3804	108	36	in	in	ADP
fnp-3804	108	37	gliomas	glioma	NOUN
fnp-3804	108	38	.	.	PUNCT
fnp-3804	109	1	dname	dname	NOUN
fnp-3804	109	2	disorder	disorder	NOUN
fnp-3804	109	3	could	could	AUX
fnp-3804	109	4	allow	allow	VERB
fnp-3804	109	5	for	for	SCONJ
fnp-3804	109	6	the	the	DET
fnp-3804	109	7	glioma	glioma	NOUN
fnp-3804	109	8	cells	cell	NOUN
fnp-3804	109	9	to	to	PART
fnp-3804	109	10	overcome	overcome	VERB
fnp-3804	109	11	environmental	environmental	ADJ
fnp-3804	109	12	stressors	stressor	NOUN
fnp-3804	109	13	and	and	CCONJ
fnp-3804	109	14	contribute	contribute	VERB
fnp-3804	109	15	to	to	ADP
fnp-3804	109	16	resistance	resistance	NOUN
fnp-3804	109	17	to	to	ADP
fnp-3804	109	18	treatment	treatment	NOUN
fnp-3804	109	19	.	.	PUNCT
fnp-3804	110	1	this	this	DET
fnp-3804	110	2	hypothesis	hypothesis	NOUN
fnp-3804	110	3	was	be	AUX
fnp-3804	110	4	tested	test	VERB
fnp-3804	110	5	in	in	ADP
fnp-3804	110	6	vitro	vitro	X
fnp-3804	110	7	by	by	ADP
fnp-3804	110	8	exposing	expose	VERB
fnp-3804	110	9	two	two	NUM
fnp-3804	110	10	glioma	glioma	NOUN
fnp-3804	110	11	cell	cell	NOUN
fnp-3804	110	12	lines	line	NOUN
fnp-3804	110	13	to	to	ADP
fnp-3804	110	14	hypoxic	hypoxic	ADJ
fnp-3804	110	15	conditions	condition	NOUN
fnp-3804	110	16	and	and	CCONJ
fnp-3804	110	17	irradiation	irradiation	NOUN
fnp-3804	110	18	.	.	PUNCT
fnp-3804	111	1	the	the	DET
fnp-3804	111	2	authors	author	NOUN
fnp-3804	111	3	found	find	VERB
fnp-3804	111	4	that	that	SCONJ
fnp-3804	111	5	under	under	ADP
fnp-3804	111	6	such	such	ADJ
fnp-3804	111	7	environmental	environmental	ADJ
fnp-3804	111	8	stressors	stressor	NOUN
fnp-3804	111	9	,	,	PUNCT
fnp-3804	111	10	dname	dname	NOUN
fnp-3804	111	11	disorder	disorder	NOUN
fnp-3804	111	12	increases	increase	VERB
fnp-3804	111	13	with	with	ADP
fnp-3804	111	14	time	time	NOUN
fnp-3804	111	15	,	,	PUNCT
fnp-3804	111	16	potentially	potentially	ADV
fnp-3804	111	17	allowing	allow	VERB
fnp-3804	111	18	the	the	DET
fnp-3804	111	19	cells	cell	NOUN
fnp-3804	111	20	to	to	PART
fnp-3804	111	21	adopt	adopt	VERB
fnp-3804	111	22	and	and	CCONJ
fnp-3804	111	23	retain	retain	VERB
fnp-3804	111	24	their	their	PRON
fnp-3804	111	25	stem	stem	NOUN
fnp-3804	111	26	-	-	PUNCT
fnp-3804	111	27	like	like	ADJ
fnp-3804	111	28	identities	identity	NOUN
fnp-3804	111	29	.	.	PUNCT
fnp-3804	112	1	topic	topic	NOUN
fnp-3804	112	2	6	6	NUM
fnp-3804	112	3	:	:	PUNCT
fnp-3804	112	4	proteogenomic	proteogenomic	ADJ
fnp-3804	112	5	and	and	CCONJ
fnp-3804	112	6	metabolomic	metabolomic	ADJ
fnp-3804	112	7	characterization	characterization	NOUN
fnp-3804	112	8	of	of	ADP
fnp-3804	112	9	glioblastoma	glioblastoma	NOUN
fnp-3804	112	10	8	8	NUM
fnp-3804	112	11	wang	wang	PROPN
fnp-3804	112	12	l	l	PROPN
fnp-3804	112	13	-	-	PROPN
fnp-3804	112	14	b	b	PROPN
fnp-3804	112	15	et	et	NOUN
fnp-3804	112	16	al	al	PROPN
fnp-3804	112	17	.	.	PUNCT
fnp-3804	113	1	(	(	PUNCT
fnp-3804	113	2	with	with	ADP
fnp-3804	113	3	the	the	DET
fnp-3804	113	4	clinical	clinical	ADJ
fnp-3804	113	5	proteomic	proteomic	ADJ
fnp-3804	113	6	tumor	tumor	NOUN
fnp-3804	113	7	analysis	analysis	NOUN
fnp-3804	113	8	consortium	consortium	NOUN
fnp-3804	113	9	)	)	PUNCT
fnp-3804	113	10	published	publish	VERB
fnp-3804	113	11	a	a	DET
fnp-3804	113	12	study	study	NOUN
fnp-3804	113	13	which	which	PRON
fnp-3804	113	14	integrated	integrate	VERB
fnp-3804	113	15	whole	whole	ADJ
fnp-3804	113	16	exome	exome	NOUN
fnp-3804	113	17	/	/	SYM
fnp-3804	113	18	whole	whole	ADJ
fnp-3804	113	19	genome	genome	NOUN
fnp-3804	113	20	sequencing	sequencing	NOUN
fnp-3804	113	21	,	,	PUNCT
fnp-3804	113	22	bulk	bulk	ADJ
fnp-3804	113	23	and	and	CCONJ
fnp-3804	113	24	single	single	ADJ
fnp-3804	113	25	-	-	PUNCT
fnp-3804	113	26	nucleus	nucleus	NOUN
fnp-3804	113	27	rna	rna	NOUN
fnp-3804	113	28	sequencing	sequencing	NOUN
fnp-3804	113	29	(	(	PUNCT
fnp-3804	113	30	rnaseq	rnaseq	NOUN
fnp-3804	113	31	)	)	PUNCT
fnp-3804	113	32	,	,	PUNCT
fnp-3804	113	33	dna	dna	PROPN
fnp-3804	113	34	methylation	methylation	NOUN
fnp-3804	113	35	,	,	PUNCT
fnp-3804	113	36	proteome	proteome	NOUN
fnp-3804	113	37	,	,	PUNCT
fnp-3804	113	38	phospho	phospho	NOUN
fnp-3804	113	39	-	-	PUNCT
fnp-3804	113	40	proteome	proteome	ADJ
fnp-3804	113	41	,	,	PUNCT
fnp-3804	113	42	acetylome	acetylome	NOUN
fnp-3804	113	43	,	,	PUNCT
fnp-3804	113	44	lipidome	lipidome	ADJ
fnp-3804	113	45	and	and	CCONJ
fnp-3804	113	46	metabolome	metabolome	NOUN
fnp-3804	113	47	datasets	dataset	NOUN
fnp-3804	113	48	for	for	ADP
fnp-3804	113	49	100	100	NUM
fnp-3804	113	50	treatment	treatment	NOUN
fnp-3804	113	51	-	-	PUNCT
fnp-3804	113	52	naïve	naïve	ADJ
fnp-3804	113	53	glioblastomas	glioblastoma	NOUN
fnp-3804	113	54	.	.	PUNCT
fnp-3804	114	1	landmark	landmark	PROPN
fnp-3804	114	2	studies	study	NOUN
fnp-3804	114	3	previously	previously	ADV
fnp-3804	114	4	already	already	ADV
fnp-3804	114	5	comprehensively	comprehensively	ADV
fnp-3804	114	6	characterized	characterize	VERB
fnp-3804	114	7	the	the	DET
fnp-3804	114	8	genome	genome	NOUN
fnp-3804	114	9	and	and	CCONJ
fnp-3804	114	10	transcriptome	transcriptome	NOUN
fnp-3804	114	11	of	of	ADP
fnp-3804	114	12	glioblastoma	glioblastoma	NOUN
fnp-3804	114	13	(	(	PUNCT
fnp-3804	114	14	see	see	VERB
fnp-3804	114	15	e.g.	e.g.	ADV
fnp-3804	114	16	28	28	NUM
fnp-3804	114	17	)	)	PUNCT
fnp-3804	114	18	.	.	PUNCT
fnp-3804	115	1	a	a	DET
fnp-3804	115	2	deep	deep	ADJ
fnp-3804	115	3	‘	'	PUNCT
fnp-3804	115	4	multi	multi	ADJ
fnp-3804	115	5	-	-	ADJ
fnp-3804	115	6	omic	omic	ADJ
fnp-3804	115	7	’	'	PUNCT
fnp-3804	115	8	approach	approach	NOUN
fnp-3804	115	9	,	,	PUNCT
fnp-3804	115	10	like	like	ADP
fnp-3804	115	11	wang	wang	PROPN
fnp-3804	115	12	l	l	PROPN
fnp-3804	115	13	-	-	PROPN
fnp-3804	115	14	b	b	PROPN
fnp-3804	115	15	et	et	PROPN
fnp-3804	115	16	al	al	PROPN
fnp-3804	115	17	.	.	PROPN
fnp-3804	115	18	undertook	undertook	PROPN
fnp-3804	115	19	,	,	PUNCT
fnp-3804	115	20	provides	provide	VERB
fnp-3804	115	21	very	very	ADV
fnp-3804	115	22	interesting	interesting	ADJ
fnp-3804	115	23	further	further	ADJ
fnp-3804	115	24	insights	insight	NOUN
fnp-3804	115	25	into	into	ADP
fnp-3804	115	26	functional	functional	ADJ
fnp-3804	115	27	and	and	CCONJ
fnp-3804	115	28	potentially	potentially	ADV
fnp-3804	115	29	targetable	targetable	ADJ
fnp-3804	115	30	differences	difference	NOUN
fnp-3804	115	31	between	between	ADP
fnp-3804	115	32	glioblastoma	glioblastoma	NOUN
fnp-3804	115	33	subtypes	subtype	NOUN
fnp-3804	115	34	.	.	PUNCT
fnp-3804	116	1	based	base	VERB
fnp-3804	116	2	on	on	ADP
fnp-3804	116	3	their	their	PRON
fnp-3804	116	4	findings	finding	NOUN
fnp-3804	116	5	,	,	PUNCT
fnp-3804	116	6	especially	especially	ADV
fnp-3804	116	7	with	with	ADP
fnp-3804	116	8	regard	regard	NOUN
fnp-3804	116	9	to	to	ADP
fnp-3804	116	10	gene	gene	NOUN
fnp-3804	116	11	expression	expression	NOUN
fnp-3804	116	12	,	,	PUNCT
fnp-3804	116	13	and	and	CCONJ
fnp-3804	116	14	protein	protein	NOUN
fnp-3804	116	15	and	and	CCONJ
fnp-3804	116	16	phosphoprotein	phosphoprotein	ADJ
fnp-3804	116	17	abundances	abundance	NOUN
fnp-3804	116	18	,	,	PUNCT
fnp-3804	116	19	wang	wang	PROPN
fnp-3804	116	20	l	l	PROPN
fnp-3804	116	21	-	-	PROPN
fnp-3804	116	22	b	b	PROPN
fnp-3804	116	23	et	et	PROPN
fnp-3804	116	24	al	al	PROPN
fnp-3804	116	25	.	.	PROPN
fnp-3804	116	26	defined	define	VERB
fnp-3804	116	27	three	three	NUM
fnp-3804	116	28	‘	'	PUNCT
fnp-3804	116	29	multi	multi	ADJ
fnp-3804	116	30	-	-	ADJ
fnp-3804	116	31	omic	omic	ADJ
fnp-3804	116	32	subtypes	subtype	NOUN
fnp-3804	116	33	’	'	PUNCT
fnp-3804	116	34	which	which	PRON
fnp-3804	116	35	closely	closely	ADV
fnp-3804	116	36	resemble	resemble	VERB
fnp-3804	116	37	tcga	tcga	NOUN
fnp-3804	116	38	(	(	PUNCT
fnp-3804	116	39	the	the	DET
fnp-3804	116	40	cancer	cancer	NOUN
fnp-3804	116	41	genome	genome	NOUN
fnp-3804	116	42	atlas	atlas	PROPN
fnp-3804	116	43	)	)	PUNCT
fnp-3804	116	44	glioma	glioma	NOUN
fnp-3804	116	45	subtypes	subtype	NOUN
fnp-3804	116	46	:	:	PUNCT
fnp-3804	116	47	the	the	DET
fnp-3804	116	48	proneural	proneural	ADJ
fnp-3804	116	49	-	-	PUNCT
fnp-3804	116	50	like	like	ADJ
fnp-3804	116	51	subtype	subtype	NOUN
fnp-3804	116	52	was	be	AUX
fnp-3804	116	53	enriched	enrich	VERB
fnp-3804	116	54	for	for	ADP
fnp-3804	116	55	neurotransmission	neurotransmission	NOUN
fnp-3804	116	56	and	and	CCONJ
fnp-3804	116	57	synaptic	synaptic	ADJ
fnp-3804	116	58	vesicle	vesicle	NOUN
fnp-3804	116	59	gene	gene	NOUN
fnp-3804	116	60	-	-	PUNCT
fnp-3804	116	61	sets	set	NOUN
fnp-3804	116	62	;	;	PUNCT
fnp-3804	116	63	the	the	DET
fnp-3804	116	64	mesenchymal	mesenchymal	NOUN
fnp-3804	116	65	-	-	PUNCT
fnp-3804	116	66	like	like	ADJ
fnp-3804	116	67	subtype	subtype	NOUN
fnp-3804	116	68	was	be	AUX
fnp-3804	116	69	enriched	enrich	VERB
fnp-3804	116	70	for	for	ADP
fnp-3804	116	71	immune	immune	ADJ
fnp-3804	116	72	system	system	NOUN
fnp-3804	116	73	activation	activation	NOUN
fnp-3804	116	74	,	,	PUNCT
fnp-3804	116	75	phagocytosis	phagocytosis	NOUN
fnp-3804	116	76	,	,	PUNCT
fnp-3804	116	77	and	and	CCONJ
fnp-3804	116	78	glycolysis	glycolysis	NOUN
fnp-3804	116	79	;	;	PUNCT
fnp-3804	116	80	finally	finally	ADV
fnp-3804	116	81	,	,	PUNCT
fnp-3804	116	82	the	the	DET
fnp-3804	116	83	classical	classical	ADJ
fnp-3804	116	84	-	-	PUNCT
fnp-3804	116	85	like	like	ADJ
fnp-3804	116	86	subtype	subtype	NOUN
fnp-3804	116	87	was	be	AUX
fnp-3804	116	88	enriched	enrich	VERB
fnp-3804	116	89	for	for	ADP
fnp-3804	116	90	chromatin	chromatin	NOUN
fnp-3804	116	91	modification	modification	NOUN
fnp-3804	116	92	,	,	PUNCT
fnp-3804	116	93	dna	dna	PROPN
fnp-3804	116	94	repair	repair	NOUN
fnp-3804	116	95	,	,	PUNCT
fnp-3804	116	96	and	and	CCONJ
fnp-3804	116	97	mrna	mrna	PROPN
fnp-3804	116	98	splicing	splicing	NOUN
fnp-3804	116	99	.	.	PUNCT
fnp-3804	117	1	the	the	DET
fnp-3804	117	2	authors	author	NOUN
fnp-3804	117	3	also	also	ADV
fnp-3804	117	4	defined	define	VERB
fnp-3804	117	5	immune	immune	NOUN
fnp-3804	117	6	-	-	PUNCT
fnp-3804	117	7	based	base	VERB
fnp-3804	117	8	subtypes	subtype	NOUN
fnp-3804	117	9	based	base	VERB
fnp-3804	117	10	on	on	ADP
fnp-3804	117	11	gene	gene	NOUN
fnp-3804	117	12	-	-	PUNCT
fnp-3804	117	13	set	set	VERB
fnp-3804	117	14	enrichment	enrichment	NOUN
fnp-3804	117	15	analysis	analysis	NOUN
fnp-3804	117	16	of	of	ADP
fnp-3804	117	17	rnaseq	rnaseq	NOUN
fnp-3804	117	18	data	datum	NOUN
fnp-3804	117	19	.	.	PUNCT
fnp-3804	118	1	subtypes	subtype	NOUN
fnp-3804	118	2	ranged	range	VERB
fnp-3804	118	3	from	from	ADP
fnp-3804	118	4	low	low	ADJ
fnp-3804	118	5	-	-	PUNCT
fnp-3804	118	6	enrichment	enrichment	NOUN
fnp-3804	118	7	of	of	ADP
fnp-3804	118	8	all	all	DET
fnp-3804	118	9	immune	immune	ADJ
fnp-3804	118	10	cells	cell	NOUN
fnp-3804	118	11	(	(	PUNCT
fnp-3804	118	12	especially	especially	ADV
fnp-3804	118	13	classical	classical	ADJ
fnp-3804	118	14	and	and	CCONJ
fnp-3804	118	15	proneural	proneural	ADJ
fnp-3804	118	16	-	-	PUNCT
fnp-3804	118	17	like	like	ADJ
fnp-3804	118	18	glioblastomas	glioblastoma	NOUN
fnp-3804	118	19	)	)	PUNCT
fnp-3804	118	20	to	to	ADP
fnp-3804	118	21	enrichment	enrichment	NOUN
fnp-3804	118	22	of	of	ADP
fnp-3804	118	23	lymphocytes	lymphocyte	NOUN
fnp-3804	118	24	,	,	PUNCT
fnp-3804	118	25	microglia	microglia	ADJ
fnp-3804	118	26	,	,	PUNCT
fnp-3804	118	27	and	and	CCONJ
fnp-3804	118	28	macrophages	macrophage	NOUN
fnp-3804	118	29	(	(	PUNCT
fnp-3804	118	30	mesenchymal	mesenchymal	NOUN
fnp-3804	118	31	-	-	PUNCT
fnp-3804	118	32	like	like	ADJ
fnp-3804	118	33	glioblastomas	glioblastoma	NOUN
fnp-3804	118	34	)	)	PUNCT
fnp-3804	118	35	.	.	PUNCT
fnp-3804	119	1	the	the	DET
fnp-3804	119	2	authors	author	NOUN
fnp-3804	119	3	integrated	integrate	VERB
fnp-3804	119	4	these	these	DET
fnp-3804	119	5	observations	observation	NOUN
fnp-3804	119	6	with	with	ADP
fnp-3804	119	7	single	single	ADJ
fnp-3804	119	8	nucleus	nucleus	ADJ
fnp-3804	119	9	rnaseq	rnaseq	NOUN
fnp-3804	119	10	of	of	ADP
fnp-3804	119	11	18	18	NUM
fnp-3804	119	12	samples	sample	NOUN
fnp-3804	119	13	spanning	span	VERB
fnp-3804	119	14	all	all	DET
fnp-3804	119	15	multi	multi	ADJ
fnp-3804	119	16	-	-	ADJ
fnp-3804	119	17	omic	omic	ADJ
fnp-3804	119	18	and	and	CCONJ
fnp-3804	119	19	immune	immune	ADJ
fnp-3804	119	20	subtypes	subtype	NOUN
fnp-3804	119	21	,	,	PUNCT
fnp-3804	119	22	and	and	CCONJ
fnp-3804	119	23	characterized	characterize	VERB
fnp-3804	119	24	expression	expression	NOUN
fnp-3804	119	25	programs	program	NOUN
fnp-3804	119	26	found	find	VERB
fnp-3804	119	27	in	in	ADP
fnp-3804	119	28	the	the	DET
fnp-3804	119	29	neoplastic	neoplastic	ADJ
fnp-3804	119	30	,	,	PUNCT
fnp-3804	119	31	stromal	stromal	ADJ
fnp-3804	119	32	,	,	PUNCT
fnp-3804	119	33	and	and	CCONJ
fnp-3804	119	34	immune	immune	ADJ
fnp-3804	119	35	cells	cell	NOUN
fnp-3804	119	36	.	.	PUNCT
fnp-3804	120	1	interestingly	interestingly	ADV
fnp-3804	120	2	,	,	PUNCT
fnp-3804	120	3	this	this	DET
fnp-3804	120	4	rnaseq	rnaseq	NOUN
fnp-3804	120	5	analysis	analysis	NOUN
fnp-3804	120	6	revealed	reveal	VERB
fnp-3804	120	7	upregulation	upregulation	NOUN
fnp-3804	120	8	of	of	ADP
fnp-3804	120	9	epithelial	epithelial	ADJ
fnp-3804	120	10	-	-	PUNCT
fnp-3804	120	11	mesenchymal	mesenchymal	NOUN
fnp-3804	120	12	transition	transition	NOUN
fnp-3804	120	13	related	relate	VERB
fnp-3804	120	14	genes	gene	NOUN
fnp-3804	120	15	in	in	ADP
fnp-3804	120	16	both	both	DET
fnp-3804	120	17	glioma	glioma	ADJ
fnp-3804	120	18	and	and	CCONJ
fnp-3804	120	19	immune	immune	ADJ
fnp-3804	120	20	cells	cell	NOUN
fnp-3804	120	21	of	of	ADP
fnp-3804	120	22	mesenchymal	mesenchymal	NOUN
fnp-3804	120	23	-	-	PUNCT
fnp-3804	120	24	like	like	ADJ
fnp-3804	120	25	glioblastomas	glioblastoma	NOUN
fnp-3804	120	26	.	.	PUNCT
fnp-3804	121	1	these	these	DET
fnp-3804	121	2	differences	difference	NOUN
fnp-3804	121	3	could	could	AUX
fnp-3804	121	4	be	be	AUX
fnp-3804	121	5	observed	observe	VERB
fnp-3804	121	6	on	on	ADP
fnp-3804	121	7	the	the	DET
fnp-3804	121	8	protein	protein	NOUN
fnp-3804	121	9	-	-	PUNCT
fnp-3804	121	10	level	level	NOUN
fnp-3804	121	11	as	as	ADV
fnp-3804	121	12	well	well	ADV
fnp-3804	121	13	.	.	PUNCT
fnp-3804	122	1	last	last	ADJ
fnp-3804	122	2	but	but	CCONJ
fnp-3804	122	3	not	not	PART
fnp-3804	122	4	least	least	ADJ
fnp-3804	122	5	,	,	PUNCT
fnp-3804	122	6	the	the	DET
fnp-3804	122	7	authors	author	NOUN
fnp-3804	122	8	also	also	ADV
fnp-3804	122	9	noticed	notice	VERB
fnp-3804	122	10	subtype	subtype	NOUN
fnp-3804	122	11	-	-	PUNCT
fnp-3804	122	12	specific	specific	ADJ
fnp-3804	122	13	enrichment	enrichment	NOUN
fnp-3804	122	14	of	of	ADP
fnp-3804	122	15	lipids	lipid	NOUN
fnp-3804	122	16	and	and	CCONJ
fnp-3804	122	17	metabolites	metabolite	NOUN
fnp-3804	122	18	.	.	PUNCT
fnp-3804	123	1	for	for	ADP
fnp-3804	123	2	example	example	NOUN
fnp-3804	123	3	,	,	PUNCT
fnp-3804	123	4	they	they	PRON
fnp-3804	123	5	noticed	notice	VERB
fnp-3804	123	6	idh	idh	NOUN
fnp-3804	123	7	mutation	mutation	NOUN
fnp-3804	123	8	status	status	NOUN
fnp-3804	123	9	-	-	PUNCT
fnp-3804	123	10	associated	associate	VERB
fnp-3804	123	11	differences	difference	NOUN
fnp-3804	123	12	in	in	ADP
fnp-3804	123	13	glycolysis	glycolysis	NOUN
fnp-3804	123	14	-	-	PUNCT
fnp-3804	123	15	related	relate	VERB
fnp-3804	123	16	metabolites	metabolite	NOUN
fnp-3804	123	17	.	.	PUNCT
fnp-3804	124	1	not	not	PART
fnp-3804	124	2	surprisingly	surprisingly	ADV
fnp-3804	124	3	,	,	PUNCT
fnp-3804	124	4	idh	idh	NOUN
fnp-3804	124	5	-	-	PUNCT
fnp-3804	124	6	mutant	mutant	NOUN
fnp-3804	124	7	gliomas	glioma	NOUN
fnp-3804	124	8	showed	show	VERB
fnp-3804	124	9	increased	increase	VERB
fnp-3804	124	10	levels	level	NOUN
fnp-3804	124	11	of	of	ADP
fnp-3804	124	12	2	2	NUM
fnp-3804	124	13	-	-	PUNCT
fnp-3804	124	14	hg	hg	NOUN
fnp-3804	124	15	,	,	PUNCT
fnp-3804	124	16	as	as	ADV
fnp-3804	124	17	well	well	ADV
fnp-3804	124	18	as	as	ADP
fnp-3804	124	19	decreased	decrease	VERB
fnp-3804	124	20	glutamate	glutamate	NOUN
fnp-3804	124	21	and	and	CCONJ
fnp-3804	124	22	serine	serine	NOUN
fnp-3804	124	23	.	.	PUNCT
fnp-3804	125	1	phosphoproteomic	phosphoproteomic	ADJ
fnp-3804	125	2	data	datum	NOUN
fnp-3804	125	3	highlighted	highlight	VERB
fnp-3804	125	4	therapeutic	therapeutic	ADJ
fnp-3804	125	5	opportunities	opportunity	NOUN
fnp-3804	125	6	for	for	ADP
fnp-3804	125	7	treating	treat	VERB
fnp-3804	125	8	glioblastoma	glioblastoma	NOUN
fnp-3804	125	9	,	,	PUNCT
fnp-3804	125	10	with	with	ADP
fnp-3804	125	11	plcg1	plcg1	NOUN
fnp-3804	125	12	and	and	CCONJ
fnp-3804	125	13	ptpn11	ptpn11	NOUN
fnp-3804	125	14	as	as	ADP
fnp-3804	125	15	signaling	signal	VERB
fnp-3804	125	16	hubs	hub	NOUN
fnp-3804	125	17	for	for	ADP
fnp-3804	125	18	receptor	receptor	NOUN
fnp-3804	125	19	tyrosine	tyrosine	NOUN
fnp-3804	125	20	kinases	kinase	NOUN
fnp-3804	125	21	.	.	PUNCT
fnp-3804	126	1	importantly	importantly	ADV
fnp-3804	126	2	,	,	PUNCT
fnp-3804	126	3	all	all	DET
fnp-3804	126	4	the	the	DET
fnp-3804	126	5	data	datum	NOUN
fnp-3804	126	6	published	publish	VERB
fnp-3804	126	7	by	by	ADP
fnp-3804	126	8	wang	wang	PROPN
fnp-3804	126	9	et	et	PROPN
fnp-3804	126	10	al	al	PROPN
fnp-3804	126	11	.	.	PROPN
fnp-3804	126	12	is	be	AUX
fnp-3804	126	13	open	open	ADJ
fnp-3804	126	14	access	access	NOUN
fnp-3804	126	15	and	and	CCONJ
fnp-3804	126	16	can	can	AUX
fnp-3804	126	17	thus	thus	ADV
fnp-3804	126	18	be	be	AUX
fnp-3804	126	19	used	use	VERB
fnp-3804	126	20	as	as	ADP
fnp-3804	126	21	a	a	DET
fnp-3804	126	22	resource	resource	NOUN
fnp-3804	126	23	for	for	ADP
fnp-3804	126	24	future	future	ADJ
fnp-3804	126	25	studies	study	NOUN
fnp-3804	126	26	of	of	ADP
fnp-3804	126	27	glioblastomas	glioblastoma	NOUN
fnp-3804	126	28	.	.	PUNCT
fnp-3804	127	1	indeed	indeed	ADV
fnp-3804	127	2	,	,	PUNCT
fnp-3804	127	3	such	such	DET
fnp-3804	127	4	a	a	DET
fnp-3804	127	5	rich	rich	ADJ
fnp-3804	127	6	dataset	dataset	NOUN
fnp-3804	127	7	adds	add	VERB
fnp-3804	127	8	depth	depth	NOUN
fnp-3804	127	9	to	to	ADP
fnp-3804	127	10	the	the	DET
fnp-3804	127	11	previous	previous	ADJ
fnp-3804	127	12	knowledge	knowledge	NOUN
fnp-3804	127	13	from	from	ADP
fnp-3804	127	14	genomic	genomic	NOUN
fnp-3804	127	15	and	and	CCONJ
fnp-3804	127	16	transcriptomic	transcriptomic	ADJ
fnp-3804	127	17	investigations	investigation	NOUN
fnp-3804	127	18	of	of	ADP
fnp-3804	127	19	glioblastomas	glioblastoma	NOUN
fnp-3804	127	20	and	and	CCONJ
fnp-3804	127	21	can	can	AUX
fnp-3804	127	22	hopefully	hopefully	ADV
fnp-3804	127	23	pave	pave	VERB
fnp-3804	127	24	the	the	DET
fnp-3804	127	25	way	way	NOUN
fnp-3804	127	26	for	for	ADP
fnp-3804	127	27	more	more	ADV
fnp-3804	127	28	effective	effective	ADJ
fnp-3804	127	29	,	,	PUNCT
fnp-3804	127	30	personalized	personalized	ADJ
fnp-3804	127	31	treatments	treatment	NOUN
fnp-3804	127	32	for	for	ADP
fnp-3804	127	33	these	these	DET
fnp-3804	127	34	tumors	tumor	NOUN
fnp-3804	127	35	.	.	PUNCT
fnp-3804	128	1	topic	topic	NOUN
fnp-3804	128	2	7	7	NUM
fnp-3804	128	3	:	:	PUNCT
fnp-3804	128	4	genomic	genomic	NOUN
fnp-3804	128	5	and	and	CCONJ
fnp-3804	128	6	immunologic	immunologic	PROPN
fnp-3804	128	7	heterogeneity	heterogeneity	NOUN
fnp-3804	128	8	of	of	ADP
fnp-3804	128	9	gliomas	glioma	NOUN
fnp-3804	128	10	and	and	CCONJ
fnp-3804	128	11	brain	brain	NOUN
fnp-3804	128	12	metastases	metastasis	NOUN
fnp-3804	128	13	9	9	NUM
fnp-3804	128	14	immunotherapies	immunotherapy	NOUN
fnp-3804	128	15	for	for	ADP
fnp-3804	128	16	primary	primary	ADJ
fnp-3804	128	17	and	and	CCONJ
fnp-3804	128	18	secondary	secondary	ADJ
fnp-3804	128	19	brain	brain	NOUN
fnp-3804	128	20	tumors	tumor	NOUN
fnp-3804	128	21	are	be	AUX
fnp-3804	128	22	a	a	DET
fnp-3804	128	23	‘	'	PUNCT
fnp-3804	128	24	hot	hot	ADJ
fnp-3804	128	25	topic	topic	NOUN
fnp-3804	128	26	’	'	PUNCT
fnp-3804	128	27	in	in	ADP
fnp-3804	128	28	the	the	DET
fnp-3804	128	29	field	field	NOUN
fnp-3804	128	30	of	of	ADP
fnp-3804	128	31	neurooncology	neurooncology	NOUN
fnp-3804	128	32	(	(	PUNCT
fnp-3804	128	33	see	see	VERB
fnp-3804	128	34	for	for	ADP
fnp-3804	128	35	example	example	NOUN
fnp-3804	128	36	also	also	ADV
fnp-3804	128	37	topic	topic	NOUN
fnp-3804	128	38	9	9	NUM
fnp-3804	128	39	of	of	ADP
fnp-3804	128	40	the	the	DET
fnp-3804	128	41	‘	'	PUNCT
fnp-3804	128	42	top	top	ADJ
fnp-3804	128	43	ten	ten	NUM
fnp-3804	128	44	discoveries	discovery	NOUN
fnp-3804	128	45	of	of	ADP
fnp-3804	128	46	the	the	DET
fnp-3804	128	47	year	year	NOUN
fnp-3804	128	48	2019	2019	NUM
fnp-3804	128	49	’	'	PUNCT
fnp-3804	128	50	review	review	NOUN
fnp-3804	128	51	in	in	ADP
fnp-3804	128	52	this	this	DET
fnp-3804	128	53	journal	journal	NOUN
fnp-3804	128	54	)	)	PUNCT
fnp-3804	128	55	.	.	PUNCT
fnp-3804	129	1	in	in	ADP
fnp-3804	129	2	2021	2021	NUM
fnp-3804	129	3	,	,	PUNCT
fnp-3804	129	4	schaettler	schaettler	NOUN
fnp-3804	129	5	mo	mo	PROPN
fnp-3804	129	6	and	and	CCONJ
fnp-3804	129	7	richters	richter	NOUN
fnp-3804	129	8	mm	mm	PROPN
fnp-3804	129	9	et	et	PROPN
fnp-3804	129	10	al	al	PROPN
fnp-3804	129	11	.	.	PUNCT
fnp-3804	130	1	(	(	PUNCT
fnp-3804	130	2	with	with	ADP
fnp-3804	130	3	griffith	griffith	PROPN
fnp-3804	130	4	m	m	PROPN
fnp-3804	130	5	and	and	CCONJ
fnp-3804	130	6	dunn	dunn	PROPN
fnp-3804	130	7	gp	gp	NOUN
fnp-3804	130	8	as	as	ADP
fnp-3804	130	9	supervising	supervise	VERB
fnp-3804	130	10	authors	author	NOUN
fnp-3804	130	11	)	)	PUNCT
fnp-3804	130	12	published	publish	VERB
fnp-3804	130	13	a	a	DET
fnp-3804	130	14	study	study	NOUN
fnp-3804	130	15	in	in	ADP
fnp-3804	130	16	cancer	cancer	NOUN
fnp-3804	130	17	discovery	discovery	NOUN
fnp-3804	130	18	investigating	investigate	VERB
fnp-3804	130	19	intra	intra	ADJ
fnp-3804	130	20	-	-	ADJ
fnp-3804	130	21	tumoral	tumoral	ADJ
fnp-3804	130	22	heterogeneity	heterogeneity	NOUN
fnp-3804	130	23	of	of	ADP
fnp-3804	130	24	somatic	somatic	ADJ
fnp-3804	130	25	variants	variant	NOUN
fnp-3804	130	26	,	,	PUNCT
fnp-3804	130	27	neo	neo	NOUN
fnp-3804	130	28	-	-	NOUN
fnp-3804	130	29	antigens	antigen	NOUN
fnp-3804	130	30	,	,	PUNCT
fnp-3804	130	31	and	and	CCONJ
fnp-3804	130	32	infiltrating	infiltrate	VERB
fnp-3804	130	33	t	t	PROPN
fnp-3804	130	34	-	-	PUNCT
fnp-3804	130	35	cells	cell	NOUN
fnp-3804	130	36	in	in	ADP
fnp-3804	130	37	gliomas	glioma	NOUN
fnp-3804	130	38	as	as	ADV
fnp-3804	130	39	well	well	ADV
fnp-3804	130	40	as	as	ADP
fnp-3804	130	41	in	in	ADP
fnp-3804	130	42	brain	brain	NOUN
fnp-3804	130	43	metastases	metastasis	NOUN
fnp-3804	130	44	.	.	PUNCT
fnp-3804	131	1	for	for	ADP
fnp-3804	131	2	this	this	DET
fnp-3804	131	3	study	study	NOUN
fnp-3804	131	4	,	,	PUNCT
fnp-3804	131	5	the	the	DET
fnp-3804	131	6	authors	author	NOUN
fnp-3804	131	7	collected	collect	VERB
fnp-3804	131	8	93	93	NUM
fnp-3804	131	9	spatially	spatially	ADV
fnp-3804	131	10	separated	separate	VERB
fnp-3804	131	11	tumor	tumor	NOUN
fnp-3804	131	12	samples	sample	NOUN
fnp-3804	131	13	from	from	ADP
fnp-3804	131	14	30	30	NUM
fnp-3804	131	15	patients	patient	NOUN
fnp-3804	131	16	.	.	PUNCT
fnp-3804	132	1	these	these	DET
fnp-3804	132	2	samples	sample	NOUN
fnp-3804	132	3	were	be	AUX
fnp-3804	132	4	subjected	subject	VERB
fnp-3804	132	5	to	to	ADP
fnp-3804	132	6	whole	whole	ADJ
fnp-3804	132	7	exome	exome	NOUN
fnp-3804	132	8	,	,	PUNCT
fnp-3804	132	9	rna	rna	NOUN
fnp-3804	132	10	and	and	CCONJ
fnp-3804	132	11	t	t	PROPN
fnp-3804	132	12	-	-	PUNCT
fnp-3804	132	13	cell	cell	NOUN
fnp-3804	132	14	receptor	receptor	NOUN
fnp-3804	132	15	sequencing	sequence	VERB
fnp-3804	132	16	(	(	PUNCT
fnp-3804	132	17	wes	wes	PROPN
fnp-3804	132	18	,	,	PUNCT
fnp-3804	132	19	rnaseq	rnaseq	NOUN
fnp-3804	132	20	,	,	PUNCT
fnp-3804	132	21	tcr	tcr	PROPN
fnp-3804	132	22	-	-	PUNCT
fnp-3804	132	23	seq	seq	PROPN
fnp-3804	132	24	)	)	PUNCT
fnp-3804	132	25	.	.	PUNCT
fnp-3804	133	1	interestingly	interestingly	ADV
fnp-3804	133	2	,	,	PUNCT
fnp-3804	133	3	while	while	SCONJ
fnp-3804	133	4	brain	brain	NOUN
fnp-3804	133	5	metastases	metastasis	NOUN
fnp-3804	133	6	had	have	VERB
fnp-3804	133	7	considerably	considerably	ADV
fnp-3804	133	8	more	more	ADV
fnp-3804	133	9	somatic	somatic	ADJ
fnp-3804	133	10	variants	variant	NOUN
fnp-3804	133	11	per	per	ADP
fnp-3804	133	12	tumor	tumor	NOUN
fnp-3804	133	13	than	than	ADP
fnp-3804	133	14	gliomas	glioma	NOUN
fnp-3804	133	15	,	,	PUNCT
fnp-3804	133	16	these	these	DET
fnp-3804	133	17	variants	variant	NOUN
fnp-3804	133	18	were	be	AUX
fnp-3804	133	19	mostly	mostly	ADV
fnp-3804	133	20	clonal	clonal	ADJ
fnp-3804	133	21	,	,	PUNCT
fnp-3804	133	22	so	so	ADV
fnp-3804	133	23	spanning	span	VERB
fnp-3804	133	24	all	all	DET
fnp-3804	133	25	tumor	tumor	NOUN
fnp-3804	133	26	samples	sample	NOUN
fnp-3804	133	27	of	of	ADP
fnp-3804	133	28	a	a	DET
fnp-3804	133	29	patient	patient	NOUN
fnp-3804	133	30	.	.	PUNCT
fnp-3804	134	1	when	when	SCONJ
fnp-3804	134	2	analyzing	analyze	VERB
fnp-3804	134	3	the	the	DET
fnp-3804	134	4	sub	sub	ADJ
fnp-3804	134	5	-	-	ADJ
fnp-3804	134	6	clonal	clonal	ADJ
fnp-3804	134	7	variants	variant	NOUN
fnp-3804	134	8	of	of	ADP
fnp-3804	134	9	gliomas	glioma	NOUN
fnp-3804	134	10	,	,	PUNCT
fnp-3804	134	11	the	the	DET
fnp-3804	134	12	authors	author	NOUN
fnp-3804	134	13	noted	note	VERB
fnp-3804	134	14	that	that	SCONJ
fnp-3804	134	15	sequencing	sequence	VERB
fnp-3804	134	16	only	only	ADV
fnp-3804	134	17	one	one	NUM
fnp-3804	134	18	region	region	NOUN
fnp-3804	134	19	of	of	ADP
fnp-3804	134	20	the	the	DET
fnp-3804	134	21	tumor	tumor	NOUN
fnp-3804	134	22	missed	miss	VERB
fnp-3804	134	23	40	40	NUM
fnp-3804	134	24	%	%	NOUN
fnp-3804	134	25	of	of	ADP
fnp-3804	134	26	variants	variant	NOUN
fnp-3804	134	27	that	that	PRON
fnp-3804	134	28	were	be	AUX
fnp-3804	134	29	obtained	obtain	VERB
fnp-3804	134	30	when	when	SCONJ
fnp-3804	134	31	sequencing	sequence	VERB
fnp-3804	134	32	three	three	NUM
fnp-3804	134	33	regions	region	NOUN
fnp-3804	134	34	.	.	PUNCT
fnp-3804	135	1	additionally	additionally	ADV
fnp-3804	135	2	,	,	PUNCT
fnp-3804	135	3	they	they	PRON
fnp-3804	135	4	found	find	VERB
fnp-3804	135	5	that	that	SCONJ
fnp-3804	135	6	9/16	9/16	NUM
fnp-3804	135	7	gliomas	glioma	NOUN
fnp-3804	135	8	in	in	ADP
fnp-3804	135	9	this	this	DET
fnp-3804	135	10	study	study	NOUN
fnp-3804	135	11	showed	show	VERB
fnp-3804	135	12	characteristics	characteristic	NOUN
fnp-3804	135	13	of	of	ADP
fnp-3804	135	14	multiple	multiple	ADJ
fnp-3804	135	15	transcriptional	transcriptional	ADJ
fnp-3804	135	16	subtypes	subtype	NOUN
fnp-3804	135	17	(	(	PUNCT
fnp-3804	135	18	classical	classical	ADJ
fnp-3804	135	19	,	,	PUNCT
fnp-3804	135	20	mesenchymal	mesenchymal	ADJ
fnp-3804	135	21	,	,	PUNCT
fnp-3804	135	22	neural	neural	ADJ
fnp-3804	135	23	and/or	and/or	CCONJ
fnp-3804	135	24	proneural	proneural	ADJ
fnp-3804	135	25	)	)	PUNCT
fnp-3804	135	26	.	.	PUNCT
fnp-3804	136	1	integrating	integrate	VERB
fnp-3804	136	2	wes	wes	PROPN
fnp-3804	136	3	and	and	CCONJ
fnp-3804	136	4	rnaseq	rnaseq	NOUN
fnp-3804	136	5	data	datum	NOUN
fnp-3804	136	6	allowed	allow	VERB
fnp-3804	136	7	the	the	DET
fnp-3804	136	8	authors	author	NOUN
fnp-3804	136	9	to	to	PART
fnp-3804	136	10	predict	predict	VERB
fnp-3804	136	11	hla	hla	PROPN
fnp-3804	136	12	class	class	NOUN
fnp-3804	136	13	i	i	PROPN
fnp-3804	136	14	and	and	CCONJ
fnp-3804	136	15	ii	ii	PROPN
fnp-3804	136	16	neo	neo	NOUN
fnp-3804	136	17	-	-	NOUN
fnp-3804	136	18	antigens	antigen	NOUN
fnp-3804	136	19	expressed	express	VERB
fnp-3804	136	20	in	in	ADP
fnp-3804	136	21	the	the	DET
fnp-3804	136	22	tumors	tumor	NOUN
fnp-3804	136	23	.	.	PUNCT
fnp-3804	137	1	they	they	PRON
fnp-3804	137	2	found	find	VERB
fnp-3804	137	3	that	that	SCONJ
fnp-3804	137	4	the	the	DET
fnp-3804	137	5	neo	neo	NOUN
fnp-3804	137	6	-	-	NOUN
fnp-3804	137	7	antigens	antigen	NOUN
fnp-3804	137	8	in	in	ADP
fnp-3804	137	9	brain	brain	NOUN
fnp-3804	137	10	metastases	metastasis	NOUN
fnp-3804	137	11	were	be	AUX
fnp-3804	137	12	more	more	ADV
fnp-3804	137	13	often	often	ADV
fnp-3804	137	14	clonal	clonal	ADJ
fnp-3804	137	15	.	.	PUNCT
fnp-3804	138	1	this	this	PRON
fnp-3804	138	2	could	could	AUX
fnp-3804	138	3	have	have	VERB
fnp-3804	138	4	implications	implication	NOUN
fnp-3804	138	5	for	for	ADP
fnp-3804	138	6	the	the	DET
fnp-3804	138	7	development	development	NOUN
fnp-3804	138	8	of	of	ADP
fnp-3804	138	9	personalized	personalized	ADJ
fnp-3804	138	10	immunotherapies	immunotherapy	NOUN
fnp-3804	138	11	,	,	PUNCT
fnp-3804	138	12	as	as	SCONJ
fnp-3804	138	13	clonal	clonal	ADJ
fnp-3804	138	14	neoantigens	neoantigen	NOUN
fnp-3804	138	15	would	would	AUX
fnp-3804	138	16	be	be	AUX
fnp-3804	138	17	better	well	ADJ
fnp-3804	138	18	targets	target	NOUN
fnp-3804	138	19	.	.	PUNCT
fnp-3804	139	1	using	use	VERB
fnp-3804	139	2	rnaseq	rnaseq	NOUN
fnp-3804	139	3	data	datum	NOUN
fnp-3804	139	4	,	,	PUNCT
fnp-3804	139	5	the	the	DET
fnp-3804	139	6	authors	author	NOUN
fnp-3804	139	7	also	also	ADV
fnp-3804	139	8	described	describe	VERB
fnp-3804	139	9	the	the	DET
fnp-3804	139	10	immune	immune	ADJ
fnp-3804	139	11	composition	composition	NOUN
fnp-3804	139	12	of	of	ADP
fnp-3804	139	13	the	the	DET
fnp-3804	139	14	tumors	tumor	NOUN
fnp-3804	139	15	.	.	PUNCT
fnp-3804	140	1	brain	brain	NOUN
fnp-3804	140	2	metastases	metastasis	NOUN
fnp-3804	140	3	had	have	VERB
fnp-3804	140	4	robust	robust	ADJ
fnp-3804	140	5	infiltration	infiltration	NOUN
fnp-3804	140	6	of	of	ADP
fnp-3804	140	7	monocyte	monocyte	NOUN
fnp-3804	140	8	-	-	PUNCT
fnp-3804	140	9	derived	derive	VERB
fnp-3804	140	10	macrophages	macrophage	NOUN
fnp-3804	140	11	,	,	PUNCT
fnp-3804	140	12	while	while	SCONJ
fnp-3804	140	13	gliomas	glioma	NOUN
fnp-3804	140	14	were	be	AUX
fnp-3804	140	15	more	more	ADV
fnp-3804	140	16	enriched	enriched	ADJ
fnp-3804	140	17	for	for	ADP
fnp-3804	140	18	microglia	microglia	ADJ
fnp-3804	140	19	gene	gene	NOUN
fnp-3804	140	20	signatures	signature	NOUN
fnp-3804	140	21	.	.	PUNCT
fnp-3804	141	1	finally	finally	ADV
fnp-3804	141	2	,	,	PUNCT
fnp-3804	141	3	the	the	DET
fnp-3804	141	4	results	result	NOUN
fnp-3804	141	5	of	of	ADP
fnp-3804	141	6	tcr	tcr	PROPN
fnp-3804	141	7	-	-	PUNCT
fnp-3804	141	8	seq	seq	NOUN
fnp-3804	141	9	analysis	analysis	NOUN
fnp-3804	141	10	revealed	reveal	VERB
fnp-3804	141	11	that	that	SCONJ
fnp-3804	141	12	spatially	spatially	ADV
fnp-3804	141	13	distinct	distinct	ADJ
fnp-3804	141	14	samples	sample	NOUN
fnp-3804	141	15	of	of	ADP
fnp-3804	141	16	brain	brain	NOUN
fnp-3804	141	17	metastases	metastasis	NOUN
fnp-3804	141	18	had	have	VERB
fnp-3804	141	19	more	more	ADV
fnp-3804	141	20	similar	similar	ADJ
fnp-3804	141	21	t	t	NOUN
fnp-3804	141	22	-	-	PUNCT
fnp-3804	141	23	cell	cell	NOUN
fnp-3804	141	24	clones	clone	NOUN
fnp-3804	141	25	than	than	ADP
fnp-3804	141	26	those	those	PRON
fnp-3804	141	27	of	of	ADP
fnp-3804	141	28	gliomas	glioma	NOUN
fnp-3804	141	29	.	.	PUNCT
fnp-3804	142	1	altogether	altogether	ADV
fnp-3804	142	2	,	,	PUNCT
fnp-3804	142	3	these	these	DET
fnp-3804	142	4	findings	finding	NOUN
fnp-3804	142	5	highlight	highlight	VERB
fnp-3804	142	6	the	the	DET
fnp-3804	142	7	considerable	considerable	ADJ
fnp-3804	142	8	intra	intra	ADJ
fnp-3804	142	9	-	-	ADJ
fnp-3804	142	10	tumoral	tumoral	ADJ
fnp-3804	142	11	heterogeneity	heterogeneity	NOUN
fnp-3804	142	12	in	in	ADP
fnp-3804	142	13	somatic	somatic	ADJ
fnp-3804	142	14	variants	variant	NOUN
fnp-3804	142	15	,	,	PUNCT
fnp-3804	142	16	transcriptome	transcriptome	NOUN
fnp-3804	142	17	,	,	PUNCT
fnp-3804	142	18	and	and	CCONJ
fnp-3804	142	19	neo	neo	NOUN
fnp-3804	142	20	-	-	NOUN
fnp-3804	142	21	antigens	antigen	NOUN
fnp-3804	142	22	of	of	ADP
fnp-3804	142	23	gliomas	glioma	NOUN
fnp-3804	142	24	.	.	PUNCT
fnp-3804	143	1	this	this	PRON
fnp-3804	143	2	can	can	AUX
fnp-3804	143	3	be	be	AUX
fnp-3804	143	4	expected	expect	VERB
fnp-3804	143	5	to	to	PART
fnp-3804	143	6	pose	pose	VERB
fnp-3804	143	7	significant	significant	ADJ
fnp-3804	143	8	challenges	challenge	NOUN
fnp-3804	143	9	for	for	ADP
fnp-3804	143	10	developing	develop	VERB
fnp-3804	143	11	effective	effective	ADJ
fnp-3804	143	12	immunotherapies	immunotherapy	NOUN
fnp-3804	143	13	.	.	PUNCT
fnp-3804	144	1	comparatively	comparatively	ADV
fnp-3804	144	2	,	,	PUNCT
fnp-3804	144	3	brain	brain	NOUN
fnp-3804	144	4	metastases	metastasis	NOUN
fnp-3804	144	5	are	be	AUX
fnp-3804	144	6	more	more	ADV
fnp-3804	144	7	homogenous	homogenous	ADJ
fnp-3804	144	8	tumors	tumor	NOUN
fnp-3804	144	9	,	,	PUNCT
fnp-3804	144	10	which	which	PRON
fnp-3804	144	11	could	could	AUX
fnp-3804	144	12	partially	partially	ADV
fnp-3804	144	13	explain	explain	VERB
fnp-3804	144	14	the	the	DET
fnp-3804	144	15	clinical	clinical	ADJ
fnp-3804	144	16	benefits	benefit	NOUN
fnp-3804	144	17	of	of	ADP
fnp-3804	144	18	immune	immune	ADJ
fnp-3804	144	19	checkpoint	checkpoint	NOUN
fnp-3804	144	20	inhibition	inhibition	NOUN
fnp-3804	144	21	when	when	SCONJ
fnp-3804	144	22	treating	treat	VERB
fnp-3804	144	23	patients	patient	NOUN
fnp-3804	144	24	with	with	ADP
fnp-3804	144	25	those	those	DET
fnp-3804	144	26	latter	latter	ADJ
fnp-3804	144	27	tumors	tumor	NOUN
fnp-3804	144	28	.	.	PUNCT
fnp-3804	145	1	topic	topic	NOUN
fnp-3804	145	2	8	8	NUM
fnp-3804	145	3	:	:	PUNCT
fnp-3804	145	4	therapeutic	therapeutic	ADJ
fnp-3804	145	5	interference	interference	NOUN
fnp-3804	145	6	with	with	ADP
fnp-3804	145	7	glioblastoma	glioblastoma	NOUN
fnp-3804	145	8	cell	cell	NOUN
fnp-3804	145	9	membranes	membrane	NOUN
fnp-3804	145	10	using	use	VERB
fnp-3804	145	11	prozac	prozac	NOUN
fnp-3804	145	12	®	®	NOUN
fnp-3804	145	13	10	10	NUM
fnp-3804	145	14	so	so	ADV
fnp-3804	145	15	far	far	ADV
fnp-3804	145	16	,	,	PUNCT
fnp-3804	145	17	little	little	ADJ
fnp-3804	145	18	progress	progress	NOUN
fnp-3804	145	19	has	have	AUX
fnp-3804	145	20	been	be	AUX
fnp-3804	145	21	made	make	VERB
fnp-3804	145	22	with	with	ADP
fnp-3804	145	23	improving	improve	VERB
fnp-3804	145	24	the	the	DET
fnp-3804	145	25	prognosis	prognosis	NOUN
fnp-3804	145	26	for	for	ADP
fnp-3804	145	27	patients	patient	NOUN
fnp-3804	145	28	with	with	ADP
fnp-3804	145	29	idh	idh	NOUN
fnp-3804	145	30	-	-	PUNCT
fnp-3804	145	31	wildtype	wildtype	NOUN
fnp-3804	145	32	glioblastomas	glioblastoma	NOUN
fnp-3804	145	33	(	(	PUNCT
fnp-3804	145	34	idh	idh	NOUN
fnp-3804	145	35	-	-	PUNCT
fnp-3804	145	36	wt	wt	NOUN
fnp-3804	145	37	gbms	gbms	NOUN
fnp-3804	145	38	)	)	PUNCT
fnp-3804	145	39	.	.	PUNCT
fnp-3804	146	1	gbms	gbms	PROPN
fnp-3804	146	2	are	be	AUX
fnp-3804	146	3	known	know	VERB
fnp-3804	146	4	to	to	PART
fnp-3804	146	5	have	have	VERB
fnp-3804	146	6	an	an	DET
fnp-3804	146	7	altered	alter	VERB
fnp-3804	146	8	lipid	lipid	NOUN
fnp-3804	146	9	composition	composition	NOUN
fnp-3804	146	10	,	,	PUNCT
fnp-3804	146	11	with	with	ADP
fnp-3804	146	12	molecular	molecular	ADJ
fnp-3804	146	13	alterations	alteration	NOUN
fnp-3804	146	14	being	be	AUX
fnp-3804	146	15	linked	link	VERB
fnp-3804	146	16	to	to	ADP
fnp-3804	146	17	differential	differential	VERB
fnp-3804	146	18	plasma	plasma	NOUN
fnp-3804	146	19	membrane	membrane	NOUN
fnp-3804	146	20	remodeling	remodeling	NOUN
fnp-3804	146	21	29	29	NUM
fnp-3804	146	22	.	.	PUNCT
fnp-3804	147	1	for	for	ADP
fnp-3804	147	2	example	example	NOUN
fnp-3804	147	3	,	,	PUNCT
fnp-3804	147	4	gbms	gbms	PROPN
fnp-3804	147	5	are	be	AUX
fnp-3804	147	6	frequently	frequently	ADV
fnp-3804	147	7	driven	drive	VERB
fnp-3804	147	8	by	by	ADP
fnp-3804	147	9	the	the	DET
fnp-3804	147	10	amplification	amplification	NOUN
fnp-3804	147	11	of	of	ADP
fnp-3804	147	12	egfr	egfr	NOUN
fnp-3804	147	13	on	on	ADP
fnp-3804	147	14	extra	extra	ADJ
fnp-3804	147	15	-	-	ADJ
fnp-3804	147	16	chromosomal	chromosomal	ADJ
fnp-3804	147	17	dna	dna	NOUN
fnp-3804	147	18	(	(	PUNCT
fnp-3804	147	19	ecdna	ecdna	ADV
fnp-3804	147	20	)	)	PUNCT
fnp-3804	147	21	.	.	PUNCT
fnp-3804	148	1	furthermore	furthermore	ADV
fnp-3804	148	2	,	,	PUNCT
fnp-3804	148	3	variants	variant	NOUN
fnp-3804	148	4	in	in	ADP
fnp-3804	148	5	the	the	DET
fnp-3804	148	6	extracellular	extracellular	ADJ
fnp-3804	148	7	egfr	egfr	NOUN
fnp-3804	148	8	domain	domain	NOUN
fnp-3804	148	9	(	(	PUNCT
fnp-3804	148	10	especially	especially	ADV
fnp-3804	148	11	egfrviii	egfrviii	NOUN
fnp-3804	148	12	)	)	PUNCT
fnp-3804	148	13	cause	cause	VERB
fnp-3804	148	14	constitutive	constitutive	ADJ
fnp-3804	148	15	activation	activation	NOUN
fnp-3804	148	16	30,31	30,31	NUM
fnp-3804	148	17	.	.	PUNCT
fnp-3804	149	1	these	these	DET
fnp-3804	149	2	signaling	signal	VERB
fnp-3804	149	3	molecules	molecule	NOUN
fnp-3804	149	4	are	be	AUX
fnp-3804	149	5	organized	organize	VERB
fnp-3804	149	6	into	into	ADP
fnp-3804	149	7	lipid	lipid	ADJ
fnp-3804	149	8	rafts	raft	NOUN
fnp-3804	149	9	on	on	ADP
fnp-3804	149	10	the	the	DET
fnp-3804	149	11	plasma	plasma	NOUN
fnp-3804	149	12	membrane	membrane	NOUN
fnp-3804	149	13	.	.	PUNCT
fnp-3804	150	1	in	in	ADP
fnp-3804	150	2	a	a	DET
fnp-3804	150	3	study	study	NOUN
fnp-3804	150	4	of	of	ADP
fnp-3804	150	5	bi	bi	PROPN
fnp-3804	150	6	j	j	PROPN
fnp-3804	150	7	et	et	PROPN
fnp-3804	150	8	al	al	PROPN
fnp-3804	150	9	.	.	PROPN
fnp-3804	150	10	published	publish	VERB
fnp-3804	150	11	in	in	ADP
fnp-3804	150	12	cell	cell	NOUN
fnp-3804	150	13	reports	report	NOUN
fnp-3804	150	14	(	(	PUNCT
fnp-3804	150	15	with	with	ADP
fnp-3804	150	16	mischel	mischel	PROPN
fnp-3804	150	17	ps	ps	PROPN
fnp-3804	150	18	as	as	ADP
fnp-3804	150	19	lead	lead	ADJ
fnp-3804	150	20	contact	contact	NOUN
fnp-3804	150	21	)	)	PUNCT
fnp-3804	150	22	,	,	PUNCT
fnp-3804	150	23	the	the	DET
fnp-3804	150	24	authors	author	NOUN
fnp-3804	150	25	identified	identify	VERB
fnp-3804	150	26	that	that	SCONJ
fnp-3804	150	27	gbms	gbms	NOUN
fnp-3804	150	28	are	be	AUX
fnp-3804	150	29	dependent	dependent	ADJ
fnp-3804	150	30	on	on	ADP
fnp-3804	150	31	sphingomyelin	sphingomyelin	NOUN
fnp-3804	150	32	phosphodiesterase	phosphodiesterase	NOUN
fnp-3804	150	33	1	1	NUM
fnp-3804	150	34	(	(	PUNCT
fnp-3804	150	35	smpd1	smpd1	NOUN
fnp-3804	150	36	)	)	PUNCT
fnp-3804	150	37	,	,	PUNCT
fnp-3804	150	38	an	an	DET
fnp-3804	150	39	enzyme	enzyme	NOUN
fnp-3804	150	40	that	that	PRON
fnp-3804	150	41	converts	convert	VERB
fnp-3804	150	42	sphingomyelin	sphingomyelin	NOUN
fnp-3804	150	43	to	to	PART
fnp-3804	150	44	ceramide	ceramide	VERB
fnp-3804	150	45	and	and	CCONJ
fnp-3804	150	46	alters	alter	VERB
fnp-3804	150	47	the	the	DET
fnp-3804	150	48	composition	composition	NOUN
fnp-3804	150	49	of	of	ADP
fnp-3804	150	50	the	the	DET
fnp-3804	150	51	plasma	plasma	NOUN
fnp-3804	150	52	membrane	membrane	NOUN
fnp-3804	150	53	.	.	PUNCT
fnp-3804	151	1	in	in	ADP
fnp-3804	151	2	the	the	DET
fnp-3804	151	3	tcga	tcga	PROPN
fnp-3804	151	4	(	(	PUNCT
fnp-3804	151	5	the	the	DET
fnp-3804	151	6	cancer	cancer	NOUN
fnp-3804	151	7	genome	genome	NOUN
fnp-3804	151	8	atlas	atlas	PROPN
fnp-3804	151	9	)	)	PUNCT
fnp-3804	151	10	cohort	cohort	NOUN
fnp-3804	151	11	of	of	ADP
fnp-3804	151	12	gbm	gbm	NOUN
fnp-3804	151	13	samples	sample	NOUN
fnp-3804	151	14	,	,	PUNCT
fnp-3804	151	15	increased	increase	VERB
fnp-3804	151	16	expression	expression	NOUN
fnp-3804	151	17	of	of	ADP
fnp-3804	151	18	smpd1	smpd1	NOUN
fnp-3804	151	19	was	be	AUX
fnp-3804	151	20	associated	associate	VERB
fnp-3804	151	21	with	with	ADP
fnp-3804	151	22	shorter	short	ADJ
fnp-3804	151	23	overall	overall	ADJ
fnp-3804	151	24	survival	survival	NOUN
fnp-3804	151	25	,	,	PUNCT
fnp-3804	151	26	suggesting	suggest	VERB
fnp-3804	151	27	that	that	SCONJ
fnp-3804	151	28	targeting	target	VERB
fnp-3804	151	29	this	this	DET
fnp-3804	151	30	pathway	pathway	NOUN
fnp-3804	151	31	could	could	AUX
fnp-3804	151	32	be	be	AUX
fnp-3804	151	33	a	a	DET
fnp-3804	151	34	therapeutic	therapeutic	ADJ
fnp-3804	151	35	strategy	strategy	NOUN
fnp-3804	151	36	for	for	ADP
fnp-3804	151	37	gbm	gbm	PROPN
fnp-3804	151	38	.	.	PUNCT
fnp-3804	152	1	interestingly	interestingly	ADV
fnp-3804	152	2	,	,	PUNCT
fnp-3804	152	3	fluoxetine	fluoxetine	NOUN
fnp-3804	152	4	(	(	PUNCT
fnp-3804	152	5	sold	sell	VERB
fnp-3804	152	6	under	under	ADP
fnp-3804	152	7	the	the	DET
fnp-3804	152	8	brand	brand	NOUN
fnp-3804	152	9	name	name	PROPN
fnp-3804	152	10	prozac	prozac	PROPN
fnp-3804	152	11	®	®	PROPN
fnp-3804	152	12	;	;	PUNCT
fnp-3804	152	13	a	a	DET
fnp-3804	152	14	brain	brain	NOUN
fnp-3804	152	15	-	-	PUNCT
fnp-3804	152	16	penetrant	penetrant	NOUN
fnp-3804	152	17	,	,	PUNCT
fnp-3804	152	18	fda	fda	PROPN
fnp-3804	152	19	-	-	PUNCT
fnp-3804	152	20	approved	approve	VERB
fnp-3804	152	21	selective	selective	ADJ
fnp-3804	152	22	serotonin	serotonin	NOUN
fnp-3804	152	23	reuptake	reuptake	NOUN
fnp-3804	152	24	inhibitor	inhibitor	NOUN
fnp-3804	152	25	(	(	PUNCT
fnp-3804	152	26	ssri	ssri	PROPN
fnp-3804	152	27	)	)	PUNCT
fnp-3804	152	28	used	use	VERB
fnp-3804	152	29	to	to	PART
fnp-3804	152	30	treat	treat	VERB
fnp-3804	152	31	multiple	multiple	ADJ
fnp-3804	152	32	psychiatric	psychiatric	ADJ
fnp-3804	152	33	disorders	disorder	NOUN
fnp-3804	152	34	)	)	PUNCT
fnp-3804	152	35	inhibits	inhibit	VERB
fnp-3804	152	36	smpd1	smpd1	NOUN
fnp-3804	152	37	activity	activity	NOUN
fnp-3804	152	38	.	.	PUNCT
fnp-3804	153	1	in	in	ADP
fnp-3804	153	2	vitro	vitro	X
fnp-3804	153	3	experiments	experiment	NOUN
fnp-3804	153	4	of	of	ADP
fnp-3804	153	5	gbm	gbm	NOUN
fnp-3804	153	6	patient	patient	NOUN
fnp-3804	153	7	-	-	PUNCT
fnp-3804	153	8	derived	derive	VERB
fnp-3804	153	9	cell	cell	NOUN
fnp-3804	153	10	lines	line	NOUN
fnp-3804	153	11	treated	treat	VERB
fnp-3804	153	12	with	with	ADP
fnp-3804	153	13	fluoxetine	fluoxetine	NOUN
fnp-3804	153	14	was	be	AUX
fnp-3804	153	15	found	find	VERB
fnp-3804	153	16	to	to	PART
fnp-3804	153	17	result	result	VERB
fnp-3804	153	18	in	in	ADP
fnp-3804	153	19	an	an	DET
fnp-3804	153	20	increase	increase	NOUN
fnp-3804	153	21	in	in	ADP
fnp-3804	153	22	lysosomal	lysosomal	ADJ
fnp-3804	153	23	stress	stress	NOUN
fnp-3804	153	24	and	and	CCONJ
fnp-3804	153	25	dose	dose	NOUN
fnp-3804	153	26	-	-	PUNCT
fnp-3804	153	27	dependent	dependent	ADJ
fnp-3804	153	28	cell	cell	NOUN
fnp-3804	153	29	death	death	NOUN
fnp-3804	153	30	.	.	PUNCT
fnp-3804	154	1	also	also	ADV
fnp-3804	154	2	,	,	PUNCT
fnp-3804	154	3	temozolomide	temozolomide	NOUN
fnp-3804	154	4	showed	show	VERB
fnp-3804	154	5	synergistic	synergistic	ADJ
fnp-3804	154	6	effects	effect	NOUN
fnp-3804	154	7	with	with	ADP
fnp-3804	154	8	fluoxetine	fluoxetine	NOUN
fnp-3804	154	9	.	.	PUNCT
fnp-3804	155	1	these	these	DET
fnp-3804	155	2	results	result	NOUN
fnp-3804	155	3	were	be	AUX
fnp-3804	155	4	confirmed	confirm	VERB
fnp-3804	155	5	in	in	ADP
fnp-3804	155	6	in	in	ADP
fnp-3804	155	7	vivo	vivo	ADJ
fnp-3804	155	8	studies	study	NOUN
fnp-3804	155	9	of	of	ADP
fnp-3804	155	10	gbm	gbm	PROPN
fnp-3804	155	11	orthotopic	orthotopic	ADJ
fnp-3804	155	12	xenografts	xenografts	PROPN
fnp-3804	155	13	,	,	PUNCT
fnp-3804	155	14	wherein	wherein	SCONJ
fnp-3804	155	15	6	6	NUM
fnp-3804	155	16	of	of	ADP
fnp-3804	155	17	8	8	NUM
fnp-3804	155	18	mice	mouse	NOUN
fnp-3804	155	19	receiving	receive	VERB
fnp-3804	155	20	both	both	PRON
fnp-3804	155	21	temozolomide	temozolomide	NOUN
fnp-3804	155	22	and	and	CCONJ
fnp-3804	155	23	fluoxetine	fluoxetine	NOUN
fnp-3804	155	24	showed	show	VERB
fnp-3804	155	25	no	no	DET
fnp-3804	155	26	tumor	tumor	NOUN
fnp-3804	155	27	recurrence	recurrence	NOUN
fnp-3804	155	28	after	after	ADP
fnp-3804	155	29	5	5	NUM
fnp-3804	155	30	months	month	NOUN
fnp-3804	155	31	of	of	ADP
fnp-3804	155	32	treatment	treatment	NOUN
fnp-3804	155	33	.	.	PUNCT
fnp-3804	156	1	over	over	ADP
fnp-3804	156	2	-	-	PUNCT
fnp-3804	156	3	expression	expression	NOUN
fnp-3804	156	4	of	of	ADP
fnp-3804	156	5	smpd1	smpd1	NOUN
fnp-3804	156	6	in	in	ADP
fnp-3804	156	7	vitro	vitro	X
fnp-3804	156	8	and	and	CCONJ
fnp-3804	156	9	in	in	ADP
fnp-3804	156	10	vivo	vivo	NOUN
fnp-3804	156	11	reversed	reverse	VERB
fnp-3804	156	12	the	the	DET
fnp-3804	156	13	effects	effect	NOUN
fnp-3804	156	14	of	of	ADP
fnp-3804	156	15	fluoxetine	fluoxetine	NOUN
fnp-3804	156	16	.	.	PUNCT
fnp-3804	157	1	next	next	ADV
fnp-3804	157	2	,	,	PUNCT
fnp-3804	157	3	the	the	DET
fnp-3804	157	4	authors	author	NOUN
fnp-3804	157	5	examined	examine	VERB
fnp-3804	157	6	electronic	electronic	ADJ
fnp-3804	157	7	medical	medical	ADJ
fnp-3804	157	8	records	record	NOUN
fnp-3804	157	9	from	from	ADP
fnp-3804	157	10	180	180	NUM
fnp-3804	157	11	million	million	NUM
fnp-3804	157	12	americans	americans	PROPN
fnp-3804	157	13	who	who	PRON
fnp-3804	157	14	were	be	AUX
fnp-3804	157	15	diagnosed	diagnose	VERB
fnp-3804	157	16	with	with	ADP
fnp-3804	157	17	gbm	gbm	PROPN
fnp-3804	157	18	between	between	ADP
fnp-3804	157	19	2003	2003	NUM
fnp-3804	157	20	and	and	CCONJ
fnp-3804	157	21	2017	2017	NUM
fnp-3804	157	22	.	.	PUNCT
fnp-3804	158	1	the	the	DET
fnp-3804	158	2	patients	patient	NOUN
fnp-3804	158	3	with	with	ADP
fnp-3804	158	4	gbm	gbm	PROPN
fnp-3804	158	5	who	who	PRON
fnp-3804	158	6	,	,	PUNCT
fnp-3804	158	7	for	for	ADP
fnp-3804	158	8	psychiatric	psychiatric	ADJ
fnp-3804	158	9	reasons	reason	NOUN
fnp-3804	158	10	,	,	PUNCT
fnp-3804	158	11	were	be	AUX
fnp-3804	158	12	also	also	ADV
fnp-3804	158	13	treated	treat	VERB
fnp-3804	158	14	with	with	ADP
fnp-3804	158	15	fluoxetine	fluoxetine	NOUN
fnp-3804	158	16	(	(	PUNCT
fnp-3804	158	17	prozac	prozac	PROPN
fnp-3804	158	18	®	®	PROPN
fnp-3804	158	19	)	)	PUNCT
fnp-3804	158	20	during	during	ADP
fnp-3804	158	21	the	the	DET
fnp-3804	158	22	disease	disease	NOUN
fnp-3804	158	23	course	course	NOUN
fnp-3804	158	24	of	of	ADP
fnp-3804	158	25	their	their	PRON
fnp-3804	158	26	brain	brain	NOUN
fnp-3804	158	27	tumor	tumor	NOUN
fnp-3804	158	28	had	have	VERB
fnp-3804	158	29	significantly	significantly	ADV
fnp-3804	158	30	longer	long	ADJ
fnp-3804	158	31	overall	overall	ADJ
fnp-3804	158	32	survival	survival	NOUN
fnp-3804	158	33	.	.	PUNCT
fnp-3804	159	1	this	this	DET
fnp-3804	159	2	result	result	NOUN
fnp-3804	159	3	was	be	AUX
fnp-3804	159	4	not	not	PART
fnp-3804	159	5	found	find	VERB
fnp-3804	159	6	for	for	ADP
fnp-3804	159	7	gbm	gbm	NOUN
fnp-3804	159	8	patients	patient	NOUN
fnp-3804	159	9	treated	treat	VERB
fnp-3804	159	10	with	with	ADP
fnp-3804	159	11	other	other	ADJ
fnp-3804	159	12	ssris	ssris	NOUN
fnp-3804	159	13	.	.	PUNCT
fnp-3804	160	1	in	in	ADP
fnp-3804	160	2	conclusion	conclusion	NOUN
fnp-3804	160	3	,	,	PUNCT
fnp-3804	160	4	the	the	DET
fnp-3804	160	5	results	result	NOUN
fnp-3804	160	6	of	of	ADP
fnp-3804	160	7	the	the	DET
fnp-3804	160	8	study	study	NOUN
fnp-3804	160	9	of	of	ADP
fnp-3804	160	10	bi	bi	PROPN
fnp-3804	160	11	et	et	PROPN
fnp-3804	160	12	al	al	PROPN
fnp-3804	160	13	.	.	PROPN
fnp-3804	160	14	indicate	indicate	VERB
fnp-3804	160	15	that	that	DET
fnp-3804	160	16	fluoxetine	fluoxetine	NOUN
fnp-3804	160	17	/	/	SYM
fnp-3804	160	18	prozac	prozac	NOUN
fnp-3804	160	19	®	®	NOUN
fnp-3804	160	20	can	can	AUX
fnp-3804	160	21	maybe	maybe	ADV
fnp-3804	160	22	be	be	AUX
fnp-3804	160	23	‘	'	PUNCT
fnp-3804	160	24	re	re	VERB
fnp-3804	160	25	-	-	VERB
fnp-3804	160	26	purposed	purposed	ADJ
fnp-3804	160	27	’	'	PUNCT
fnp-3804	160	28	and	and	CCONJ
fnp-3804	160	29	integrated	integrate	VERB
fnp-3804	160	30	with	with	ADP
fnp-3804	160	31	standard	standard	NOUN
fnp-3804	160	32	of	of	ADP
fnp-3804	160	33	care	care	NOUN
fnp-3804	160	34	of	of	ADP
fnp-3804	160	35	patients	patient	NOUN
fnp-3804	160	36	diagnosed	diagnose	VERB
fnp-3804	160	37	with	with	ADP
fnp-3804	160	38	gbm	gbm	NOUN
fnp-3804	160	39	in	in	ADP
fnp-3804	160	40	order	order	NOUN
fnp-3804	160	41	to	to	PART
fnp-3804	160	42	help	help	VERB
fnp-3804	160	43	improve	improve	VERB
fnp-3804	160	44	their	their	PRON
fnp-3804	160	45	survival	survival	NOUN
fnp-3804	160	46	.	.	PUNCT
fnp-3804	161	1	obviously	obviously	ADV
fnp-3804	161	2	,	,	PUNCT
fnp-3804	161	3	controlled	control	VERB
fnp-3804	161	4	clinical	clinical	ADJ
fnp-3804	161	5	trials	trial	NOUN
fnp-3804	161	6	are	be	AUX
fnp-3804	161	7	necessary	necessary	ADJ
fnp-3804	161	8	to	to	PART
fnp-3804	161	9	substantiate	substantiate	VERB
fnp-3804	161	10	this	this	DET
fnp-3804	161	11	idea	idea	NOUN
fnp-3804	161	12	further	far	ADV
fnp-3804	161	13	.	.	PUNCT
fnp-3804	162	1	also	also	ADV
fnp-3804	162	2	,	,	PUNCT
fnp-3804	162	3	it	it	PRON
fnp-3804	162	4	would	would	AUX
fnp-3804	162	5	be	be	AUX
fnp-3804	162	6	interesting	interesting	ADJ
fnp-3804	162	7	to	to	PART
fnp-3804	162	8	learn	learn	VERB
fnp-3804	162	9	more	more	ADJ
fnp-3804	162	10	about	about	ADP
fnp-3804	162	11	other	other	ADJ
fnp-3804	162	12	compounds	compound	NOUN
fnp-3804	162	13	that	that	PRON
fnp-3804	162	14	might	might	AUX
fnp-3804	162	15	be	be	AUX
fnp-3804	162	16	good	good	ADJ
fnp-3804	162	17	candidates	candidate	NOUN
fnp-3804	162	18	for	for	ADP
fnp-3804	162	19	therapeutic	therapeutic	ADJ
fnp-3804	162	20	interference	interference	NOUN
fnp-3804	162	21	with	with	ADP
fnp-3804	162	22	(	(	PUNCT
fnp-3804	162	23	the	the	DET
fnp-3804	162	24	composition	composition	NOUN
fnp-3804	162	25	of	of	ADP
fnp-3804	162	26	)	)	PUNCT
fnp-3804	162	27	gbm	gbm	NOUN
fnp-3804	162	28	cell	cell	NOUN
fnp-3804	162	29	membranes	membrane	NOUN
fnp-3804	162	30	.	.	PUNCT
fnp-3804	163	1	topic	topic	NOUN
fnp-3804	163	2	9	9	NUM
fnp-3804	163	3	:	:	PUNCT
fnp-3804	163	4	liquid	liquid	ADJ
fnp-3804	163	5	biopsy	biopsy	NOUN
fnp-3804	163	6	assessment	assessment	NOUN
fnp-3804	163	7	of	of	ADP
fnp-3804	163	8	residual	residual	ADJ
fnp-3804	163	9	medulloblastoma	medulloblastoma	NOUN
fnp-3804	163	10	11	11	NUM
fnp-3804	163	11	a	a	DET
fnp-3804	163	12	current	current	ADJ
fnp-3804	163	13	problem	problem	NOUN
fnp-3804	163	14	in	in	ADP
fnp-3804	163	15	the	the	DET
fnp-3804	163	16	management	management	NOUN
fnp-3804	163	17	of	of	ADP
fnp-3804	163	18	children	child	NOUN
fnp-3804	163	19	with	with	ADP
fnp-3804	163	20	medulloblastoma	medulloblastoma	NOUN
fnp-3804	163	21	is	be	AUX
fnp-3804	163	22	assessing	assess	VERB
fnp-3804	163	23	residual	residual	ADJ
fnp-3804	163	24	disease	disease	NOUN
fnp-3804	163	25	during	during	ADP
fnp-3804	163	26	treatment	treatment	NOUN
fnp-3804	163	27	and	and	CCONJ
fnp-3804	163	28	predicting	predicting	NOUN
fnp-3804	163	29	which	which	PRON
fnp-3804	163	30	patients	patient	NOUN
fnp-3804	163	31	relapse	relapse	VERB
fnp-3804	163	32	locally	locally	ADV
fnp-3804	163	33	or	or	CCONJ
fnp-3804	163	34	through	through	ADP
fnp-3804	163	35	dissemination	dissemination	NOUN
fnp-3804	163	36	to	to	ADP
fnp-3804	163	37	the	the	DET
fnp-3804	163	38	leptomeninges	leptomeninge	NOUN
fnp-3804	163	39	(	(	PUNCT
fnp-3804	163	40	which	which	PRON
fnp-3804	163	41	,	,	PUNCT
fnp-3804	163	42	unfortunately	unfortunately	ADV
fnp-3804	163	43	,	,	PUNCT
fnp-3804	163	44	frequently	frequently	ADV
fnp-3804	163	45	leads	lead	VERB
fnp-3804	163	46	to	to	ADP
fnp-3804	163	47	death	death	NOUN
fnp-3804	163	48	)	)	PUNCT
fnp-3804	163	49	32	32	NUM
fnp-3804	163	50	.	.	PUNCT
fnp-3804	164	1	currently	currently	ADV
fnp-3804	164	2	,	,	PUNCT
fnp-3804	164	3	mri	mri	NOUN
fnp-3804	164	4	and	and	CCONJ
fnp-3804	164	5	cytology	cytology	NOUN
fnp-3804	164	6	assessment	assessment	NOUN
fnp-3804	164	7	of	of	ADP
fnp-3804	164	8	the	the	DET
fnp-3804	164	9	cerebrospinal	cerebrospinal	ADJ
fnp-3804	164	10	fluid	fluid	NOUN
fnp-3804	164	11	(	(	PUNCT
fnp-3804	164	12	csf	csf	NOUN
fnp-3804	164	13	)	)	PUNCT
fnp-3804	164	14	are	be	AUX
fnp-3804	164	15	used	use	VERB
fnp-3804	164	16	to	to	PART
fnp-3804	164	17	detect	detect	VERB
fnp-3804	164	18	relapse	relapse	NOUN
fnp-3804	164	19	.	.	PUNCT
fnp-3804	165	1	however	however	ADV
fnp-3804	165	2	,	,	PUNCT
fnp-3804	165	3	these	these	DET
fnp-3804	165	4	diagnostic	diagnostic	ADJ
fnp-3804	165	5	modalities	modality	NOUN
fnp-3804	165	6	are	be	AUX
fnp-3804	165	7	generally	generally	ADV
fnp-3804	165	8	only	only	ADV
fnp-3804	165	9	useful	useful	ADJ
fnp-3804	165	10	once	once	SCONJ
fnp-3804	165	11	the	the	DET
fnp-3804	165	12	tumor	tumor	NOUN
fnp-3804	165	13	has	have	AUX
fnp-3804	165	14	progressed	progress	VERB
fnp-3804	165	15	substantially	substantially	ADV
fnp-3804	165	16	.	.	PUNCT
fnp-3804	166	1	medulloblastomas	medulloblastoma	NOUN
fnp-3804	166	2	typically	typically	ADV
fnp-3804	166	3	have	have	VERB
fnp-3804	166	4	few	few	ADJ
fnp-3804	166	5	driver	driver	NOUN
fnp-3804	166	6	mutations	mutation	NOUN
fnp-3804	166	7	and	and	CCONJ
fnp-3804	166	8	are	be	AUX
fnp-3804	166	9	characterized	characterize	VERB
fnp-3804	166	10	by	by	ADP
fnp-3804	166	11	high	high	ADJ
fnp-3804	166	12	levels	level	NOUN
fnp-3804	166	13	of	of	ADP
fnp-3804	166	14	chromosomal	chromosomal	ADJ
fnp-3804	166	15	instability	instability	NOUN
fnp-3804	166	16	(	(	PUNCT
fnp-3804	166	17	copy	copy	VERB
fnp-3804	166	18	number	number	NOUN
fnp-3804	166	19	variants	variant	NOUN
fnp-3804	166	20	)	)	PUNCT
fnp-3804	166	21	.	.	PUNCT
fnp-3804	167	1	in	in	ADP
fnp-3804	167	2	a	a	DET
fnp-3804	167	3	study	study	NOUN
fnp-3804	167	4	from	from	ADP
fnp-3804	167	5	2020	2020	NUM
fnp-3804	167	6	,	,	PUNCT
fnp-3804	167	7	escudero	escudero	PROPN
fnp-3804	167	8	et	et	PROPN
fnp-3804	167	9	al	al	PROPN
fnp-3804	167	10	.	.	PROPN
fnp-3804	167	11	found	find	VERB
fnp-3804	167	12	that	that	SCONJ
fnp-3804	167	13	csf	csf	ADJ
fnp-3804	167	14	-	-	PUNCT
fnp-3804	167	15	derived	derive	VERB
fnp-3804	167	16	cell	cell	NOUN
fnp-3804	167	17	-	-	PUNCT
fnp-3804	167	18	free	free	ADJ
fnp-3804	167	19	dna	dna	NOUN
fnp-3804	167	20	(	(	PUNCT
fnp-3804	167	21	cfdna	cfdna	NOUN
fnp-3804	167	22	)	)	PUNCT
fnp-3804	167	23	recapitulated	recapitulate	VERB
fnp-3804	167	24	molecular	molecular	ADJ
fnp-3804	167	25	characteristics	characteristic	NOUN
fnp-3804	167	26	of	of	ADP
fnp-3804	167	27	the	the	DET
fnp-3804	167	28	initial	initial	ADJ
fnp-3804	167	29	medulloblastomas	medulloblastoma	NOUN
fnp-3804	167	30	,	,	PUNCT
fnp-3804	167	31	including	include	VERB
fnp-3804	167	32	the	the	DET
fnp-3804	167	33	oncogenic	oncogenic	ADJ
fnp-3804	167	34	drivers	driver	NOUN
fnp-3804	167	35	33	33	NUM
fnp-3804	167	36	.	.	PUNCT
fnp-3804	168	1	cfdna	cfdna	NOUN
fnp-3804	168	2	from	from	ADP
fnp-3804	168	3	the	the	DET
fnp-3804	168	4	csf	csf	NOUN
fnp-3804	168	5	could	could	AUX
fnp-3804	168	6	also	also	ADV
fnp-3804	168	7	be	be	AUX
fnp-3804	168	8	used	use	VERB
fnp-3804	168	9	to	to	PART
fnp-3804	168	10	classify	classify	VERB
fnp-3804	168	11	medulloblastomas	medulloblastoma	NOUN
fnp-3804	168	12	into	into	ADP
fnp-3804	168	13	the	the	DET
fnp-3804	168	14	four	four	NUM
fnp-3804	168	15	molecular	molecular	ADJ
fnp-3804	168	16	sub	sub	NOUN
fnp-3804	168	17	-	-	NOUN
fnp-3804	168	18	groups	group	NOUN
fnp-3804	168	19	.	.	PUNCT
fnp-3804	169	1	following	follow	VERB
fnp-3804	169	2	up	up	ADP
fnp-3804	169	3	on	on	ADP
fnp-3804	169	4	these	these	DET
fnp-3804	169	5	findings	finding	NOUN
fnp-3804	169	6	,	,	PUNCT
fnp-3804	169	7	liu	liu	PROPN
fnp-3804	169	8	api	api	PROPN
fnp-3804	169	9	,	,	PUNCT
fnp-3804	169	10	smith	smith	PROPN
fnp-3804	169	11	ks	ks	PROPN
fnp-3804	169	12	,	,	PUNCT
fnp-3804	169	13	and	and	CCONJ
fnp-3804	169	14	kumar	kumar	PROPN
fnp-3804	169	15	r	r	PROPN
fnp-3804	169	16	et	et	PROPN
fnp-3804	169	17	al	al	PROPN
fnp-3804	169	18	.	.	PUNCT
fnp-3804	170	1	(	(	PUNCT
fnp-3804	170	2	with	with	ADP
fnp-3804	170	3	gajjar	gajjar	NOUN
fnp-3804	170	4	a	a	PRON
fnp-3804	170	5	,	,	PUNCT
fnp-3804	170	6	robinson	robinson	PROPN
fnp-3804	170	7	gw	gw	PROPN
fnp-3804	170	8	and	and	CCONJ
fnp-3804	170	9	northcott	northcott	PROPN
fnp-3804	170	10	pa	pa	PROPN
fnp-3804	170	11	as	as	ADP
fnp-3804	170	12	senior	senior	ADJ
fnp-3804	170	13	authors	author	NOUN
fnp-3804	170	14	)	)	PUNCT
fnp-3804	170	15	published	publish	VERB
fnp-3804	170	16	a	a	DET
fnp-3804	170	17	paper	paper	NOUN
fnp-3804	170	18	in	in	ADP
fnp-3804	170	19	cancer	cancer	NOUN
fnp-3804	170	20	cell	cell	NOUN
fnp-3804	170	21	evaluating	evaluate	VERB
fnp-3804	170	22	the	the	DET
fnp-3804	170	23	utility	utility	NOUN
fnp-3804	170	24	of	of	ADP
fnp-3804	170	25	cfdna	cfdna	NOUN
fnp-3804	170	26	to	to	PART
fnp-3804	170	27	assess	assess	VERB
fnp-3804	170	28	measurable	measurable	ADJ
fnp-3804	170	29	residual	residual	ADJ
fnp-3804	170	30	disease	disease	NOUN
fnp-3804	170	31	(	(	PUNCT
fnp-3804	170	32	mrd	mrd	PROPN
fnp-3804	170	33	)	)	PUNCT
fnp-3804	170	34	for	for	ADP
fnp-3804	170	35	guiding	guide	VERB
fnp-3804	170	36	the	the	DET
fnp-3804	170	37	therapeutic	therapeutic	ADJ
fnp-3804	170	38	management	management	NOUN
fnp-3804	170	39	of	of	ADP
fnp-3804	170	40	medulloblastoma	medulloblastoma	ADJ
fnp-3804	170	41	patients	patient	NOUN
fnp-3804	170	42	11	11	NUM
fnp-3804	170	43	.	.	PUNCT
fnp-3804	171	1	they	they	PRON
fnp-3804	171	2	performed	perform	VERB
fnp-3804	171	3	low	low	ADJ
fnp-3804	171	4	-	-	PUNCT
fnp-3804	171	5	coverage	coverage	NOUN
fnp-3804	171	6	whole	whole	ADJ
fnp-3804	171	7	genome	genome	NOUN
fnp-3804	171	8	sequencing	sequencing	NOUN
fnp-3804	171	9	on	on	ADP
fnp-3804	171	10	cfdna	cfdna	NOUN
fnp-3804	171	11	from	from	ADP
fnp-3804	171	12	476	476	NUM
fnp-3804	171	13	csf	csf	ADJ
fnp-3804	171	14	samples	sample	NOUN
fnp-3804	171	15	,	,	PUNCT
fnp-3804	171	16	representing	represent	VERB
fnp-3804	171	17	123	123	NUM
fnp-3804	171	18	patients	patient	NOUN
fnp-3804	171	19	,	,	PUNCT
fnp-3804	171	20	and	and	CCONJ
fnp-3804	171	21	derived	derived	ADJ
fnp-3804	171	22	cnvs	cnvs	NOUN
fnp-3804	171	23	as	as	ADP
fnp-3804	171	24	a	a	DET
fnp-3804	171	25	biomarker	biomarker	NOUN
fnp-3804	171	26	for	for	ADP
fnp-3804	171	27	mrd	mrd	PROPN
fnp-3804	171	28	.	.	PUNCT
fnp-3804	172	1	of	of	ADP
fnp-3804	172	2	the	the	DET
fnp-3804	172	3	105	105	NUM
fnp-3804	172	4	csf	csf	ADJ
fnp-3804	172	5	samples	sample	NOUN
fnp-3804	172	6	collected	collect	VERB
fnp-3804	172	7	at	at	ADP
fnp-3804	172	8	baseline	baseline	NOUN
fnp-3804	172	9	,	,	PUNCT
fnp-3804	172	10	the	the	DET
fnp-3804	172	11	authors	author	NOUN
fnp-3804	172	12	detected	detect	VERB
fnp-3804	172	13	cnvs	cnvs	NOUN
fnp-3804	172	14	in	in	ADP
fnp-3804	172	15	64	64	NUM
fnp-3804	172	16	%	%	NOUN
fnp-3804	172	17	of	of	ADP
fnp-3804	172	18	the	the	DET
fnp-3804	172	19	samples	sample	NOUN
fnp-3804	172	20	.	.	PUNCT
fnp-3804	173	1	cnvs	cnvs	NOUN
fnp-3804	173	2	were	be	AUX
fnp-3804	173	3	not	not	PART
fnp-3804	173	4	detected	detect	VERB
fnp-3804	173	5	in	in	ADP
fnp-3804	173	6	cfdna	cfdna	NOUN
fnp-3804	173	7	from	from	ADP
fnp-3804	173	8	csf	csf	NOUN
fnp-3804	173	9	of	of	ADP
fnp-3804	173	10	patients	patient	NOUN
fnp-3804	173	11	without	without	ADP
fnp-3804	173	12	oncological	oncological	ADJ
fnp-3804	173	13	diseases	disease	NOUN
fnp-3804	173	14	that	that	PRON
fnp-3804	173	15	were	be	AUX
fnp-3804	173	16	used	use	VERB
fnp-3804	173	17	as	as	ADP
fnp-3804	173	18	control	control	NOUN
fnp-3804	173	19	.	.	PUNCT
fnp-3804	174	1	using	use	VERB
fnp-3804	174	2	multivariate	multivariate	NOUN
fnp-3804	174	3	regression	regression	NOUN
fnp-3804	174	4	,	,	PUNCT
fnp-3804	174	5	they	they	PRON
fnp-3804	174	6	found	find	VERB
fnp-3804	174	7	that	that	PRON
fnp-3804	174	8	detection	detection	NOUN
fnp-3804	174	9	of	of	ADP
fnp-3804	174	10	baseline	baseline	ADJ
fnp-3804	174	11	samples	sample	NOUN
fnp-3804	174	12	was	be	AUX
fnp-3804	174	13	associated	associate	VERB
fnp-3804	174	14	with	with	ADP
fnp-3804	174	15	tumor	tumor	NOUN
fnp-3804	174	16	location	location	NOUN
fnp-3804	174	17	and	and	CCONJ
fnp-3804	174	18	subgroup	subgroup	NOUN
fnp-3804	174	19	,	,	PUNCT
fnp-3804	174	20	wherein	wherein	ADJ
fnp-3804	174	21	detection	detection	NOUN
fnp-3804	174	22	was	be	AUX
fnp-3804	174	23	lowest	low	ADJ
fnp-3804	174	24	for	for	ADP
fnp-3804	174	25	tumors	tumor	NOUN
fnp-3804	174	26	centered	center	VERB
fnp-3804	174	27	within	within	ADP
fnp-3804	174	28	cerebellar	cerebellar	ADJ
fnp-3804	174	29	hemispheres	hemisphere	NOUN
fnp-3804	174	30	or	or	CCONJ
fnp-3804	174	31	vermis	vermis	NOUN
fnp-3804	174	32	,	,	PUNCT
fnp-3804	174	33	and	and	CCONJ
fnp-3804	174	34	for	for	ADP
fnp-3804	174	35	the	the	DET
fnp-3804	174	36	shh	shh	PROPN
fnp-3804	174	37	subgroup	subgroup	PROPN
fnp-3804	174	38	.	.	PUNCT
fnp-3804	175	1	additionally	additionally	ADV
fnp-3804	175	2	,	,	PUNCT
fnp-3804	175	3	the	the	DET
fnp-3804	175	4	detection	detection	NOUN
fnp-3804	175	5	of	of	ADP
fnp-3804	175	6	mrd	mrd	PROPN
fnp-3804	175	7	in	in	ADP
fnp-3804	175	8	samples	sample	NOUN
fnp-3804	175	9	post	post	NOUN
fnp-3804	175	10	-	-	NOUN
fnp-3804	175	11	radiotherapy	radiotherapy	ADJ
fnp-3804	175	12	,	,	PUNCT
fnp-3804	175	13	mid	mid	NOUN
fnp-3804	175	14	-	-	NOUN
fnp-3804	175	15	chemotherapy	chemotherapy	NOUN
fnp-3804	175	16	,	,	PUNCT
fnp-3804	175	17	or	or	CCONJ
fnp-3804	175	18	at	at	ADP
fnp-3804	175	19	the	the	DET
fnp-3804	175	20	end	end	NOUN
fnp-3804	175	21	of	of	ADP
fnp-3804	175	22	therapy	therapy	NOUN
fnp-3804	175	23	was	be	AUX
fnp-3804	175	24	associated	associate	VERB
fnp-3804	175	25	with	with	ADP
fnp-3804	175	26	worse	bad	ADJ
fnp-3804	175	27	progression	progression	NOUN
fnp-3804	175	28	free	free	ADJ
fnp-3804	175	29	survival	survival	NOUN
fnp-3804	175	30	(	(	PUNCT
fnp-3804	175	31	pfs	pfs	PROPN
fnp-3804	175	32	)	)	PUNCT
fnp-3804	175	33	,	,	PUNCT
fnp-3804	175	34	while	while	SCONJ
fnp-3804	175	35	baseline	baseline	ADJ
fnp-3804	175	36	cnv	cnv	PROPN
fnp-3804	175	37	detection	detection	NOUN
fnp-3804	175	38	was	be	AUX
fnp-3804	175	39	not	not	PART
fnp-3804	175	40	prognostic	prognostic	ADJ
fnp-3804	175	41	for	for	ADP
fnp-3804	175	42	pfs	pfs	PROPN
fnp-3804	175	43	.	.	PUNCT
fnp-3804	176	1	the	the	DET
fnp-3804	176	2	authors	author	NOUN
fnp-3804	176	3	did	do	AUX
fnp-3804	176	4	find	find	VERB
fnp-3804	176	5	a	a	DET
fnp-3804	176	6	high	high	ADJ
fnp-3804	176	7	correlation	correlation	NOUN
fnp-3804	176	8	between	between	ADP
fnp-3804	176	9	cnvs	cnvs	NOUN
fnp-3804	176	10	detected	detect	VERB
fnp-3804	176	11	at	at	ADP
fnp-3804	176	12	baseline	baseline	NOUN
fnp-3804	176	13	in	in	ADP
fnp-3804	176	14	the	the	DET
fnp-3804	176	15	csf	csf	NOUN
fnp-3804	176	16	and	and	CCONJ
fnp-3804	176	17	in	in	ADP
fnp-3804	176	18	the	the	DET
fnp-3804	176	19	primary	primary	ADJ
fnp-3804	176	20	tumor	tumor	NOUN
fnp-3804	176	21	,	,	PUNCT
fnp-3804	176	22	confirming	confirm	VERB
fnp-3804	176	23	the	the	DET
fnp-3804	176	24	results	result	NOUN
fnp-3804	176	25	from	from	ADP
fnp-3804	176	26	escudero	escudero	PROPN
fnp-3804	176	27	et	et	PROPN
fnp-3804	176	28	al	al	PROPN
fnp-3804	176	29	.	.	PROPN
fnp-3804	176	30	comparing	compare	VERB
fnp-3804	176	31	serial	serial	ADJ
fnp-3804	176	32	samples	sample	NOUN
fnp-3804	176	33	of	of	ADP
fnp-3804	176	34	cfdna	cfdna	NOUN
fnp-3804	176	35	,	,	PUNCT
fnp-3804	176	36	75	75	NUM
fnp-3804	176	37	%	%	NOUN
fnp-3804	176	38	of	of	ADP
fnp-3804	176	39	patients	patient	NOUN
fnp-3804	176	40	had	have	VERB
fnp-3804	176	41	a	a	DET
fnp-3804	176	42	more	more	ADV
fnp-3804	176	43	‘	'	PUNCT
fnp-3804	176	44	unstable	unstable	ADJ
fnp-3804	176	45	’	'	PUNCT
fnp-3804	176	46	genome	genome	NOUN
fnp-3804	176	47	with	with	ADP
fnp-3804	176	48	a	a	DET
fnp-3804	176	49	loss	loss	NOUN
fnp-3804	176	50	of	of	ADP
fnp-3804	176	51	chromosome	chromosome	NOUN
fnp-3804	176	52	10q	10q	NOUN
fnp-3804	176	53	at	at	ADP
fnp-3804	176	54	recurrence	recurrence	NOUN
fnp-3804	176	55	.	.	PUNCT
fnp-3804	177	1	mrd	mrd	PROPN
fnp-3804	177	2	was	be	AUX
fnp-3804	177	3	detected	detect	VERB
fnp-3804	177	4	for	for	ADP
fnp-3804	177	5	all	all	DET
fnp-3804	177	6	patients	patient	NOUN
fnp-3804	177	7	with	with	ADP
fnp-3804	177	8	persistent	persistent	ADJ
fnp-3804	177	9	disease	disease	NOUN
fnp-3804	177	10	recurrence	recurrence	NOUN
fnp-3804	177	11	,	,	PUNCT
fnp-3804	177	12	demonstrating	demonstrate	VERB
fnp-3804	177	13	the	the	DET
fnp-3804	177	14	high	high	ADJ
fnp-3804	177	15	accuracy	accuracy	NOUN
fnp-3804	177	16	for	for	ADP
fnp-3804	177	17	this	this	DET
fnp-3804	177	18	assay	assay	NOUN
fnp-3804	177	19	.	.	PUNCT
fnp-3804	178	1	of	of	ADP
fnp-3804	178	2	note	note	NOUN
fnp-3804	178	3	,	,	PUNCT
fnp-3804	178	4	of	of	ADP
fnp-3804	178	5	the	the	DET
fnp-3804	178	6	patients	patient	NOUN
fnp-3804	178	7	with	with	ADP
fnp-3804	178	8	medulloblastoma	medulloblastoma	ADJ
fnp-3804	178	9	recurrence	recurrence	NOUN
fnp-3804	178	10	,	,	PUNCT
fnp-3804	178	11	mrd	mrd	PROPN
fnp-3804	178	12	was	be	AUX
fnp-3804	178	13	detected	detect	VERB
fnp-3804	178	14	by	by	ADP
fnp-3804	178	15	csf	csf	ADJ
fnp-3804	178	16	cfdna	cfdna	NOUN
fnp-3804	178	17	analysis	analysis	NOUN
fnp-3804	178	18	at	at	ADV
fnp-3804	178	19	least	least	ADV
fnp-3804	178	20	3	3	NUM
fnp-3804	178	21	months	month	NOUN
fnp-3804	178	22	before	before	ADP
fnp-3804	178	23	appearing	appear	VERB
fnp-3804	178	24	on	on	ADP
fnp-3804	178	25	mri	mri	NOUN
fnp-3804	178	26	or	or	CCONJ
fnp-3804	178	27	based	base	VERB
fnp-3804	178	28	on	on	ADP
fnp-3804	178	29	cytology	cytology	NOUN
fnp-3804	178	30	analysis	analysis	NOUN
fnp-3804	178	31	.	.	PUNCT
fnp-3804	179	1	this	this	DET
fnp-3804	179	2	study	study	NOUN
fnp-3804	179	3	demonstrates	demonstrate	VERB
fnp-3804	179	4	that	that	DET
fnp-3804	179	5	detection	detection	NOUN
fnp-3804	179	6	of	of	ADP
fnp-3804	179	7	cnvs	cnvs	NOUN
fnp-3804	179	8	from	from	ADP
fnp-3804	179	9	csf	csf	ADJ
fnp-3804	179	10	-	-	PUNCT
fnp-3804	179	11	derived	derive	VERB
fnp-3804	179	12	cfdna	cfdna	NOUN
fnp-3804	179	13	may	may	AUX
fnp-3804	179	14	allow	allow	VERB
fnp-3804	179	15	for	for	ADP
fnp-3804	179	16	a	a	DET
fnp-3804	179	17	more	more	ADV
fnp-3804	179	18	sensitive	sensitive	ADJ
fnp-3804	179	19	evaluation	evaluation	NOUN
fnp-3804	179	20	of	of	ADP
fnp-3804	179	21	disease	disease	NOUN
fnp-3804	179	22	progression	progression	NOUN
fnp-3804	179	23	in	in	ADP
fnp-3804	179	24	children	child	NOUN
fnp-3804	179	25	with	with	ADP
fnp-3804	179	26	medulloblastoma	medulloblastoma	NOUN
fnp-3804	179	27	than	than	ADP
fnp-3804	179	28	the	the	DET
fnp-3804	179	29	currently	currently	ADV
fnp-3804	179	30	available	available	ADJ
fnp-3804	179	31	tools	tool	NOUN
fnp-3804	179	32	.	.	PUNCT
fnp-3804	180	1	the	the	DET
fnp-3804	180	2	authors	author	NOUN
fnp-3804	180	3	therefore	therefore	ADV
fnp-3804	180	4	advocate	advocate	VERB
fnp-3804	180	5	for	for	ADP
fnp-3804	180	6	incorporating	incorporate	VERB
fnp-3804	180	7	such	such	ADJ
fnp-3804	180	8	cfdna	cfdna	NOUN
fnp-3804	180	9	analysis	analysis	NOUN
fnp-3804	180	10	of	of	ADP
fnp-3804	180	11	liquid	liquid	ADJ
fnp-3804	180	12	biopsies	biopsy	NOUN
fnp-3804	180	13	to	to	PART
fnp-3804	180	14	inform	inform	VERB
fnp-3804	180	15	management	management	NOUN
fnp-3804	180	16	of	of	ADP
fnp-3804	180	17	these	these	DET
fnp-3804	180	18	aggressive	aggressive	ADJ
fnp-3804	180	19	cancers	cancer	NOUN
fnp-3804	180	20	.	.	PUNCT
fnp-3804	181	1	topic	topic	NOUN
fnp-3804	181	2	10	10	NUM
fnp-3804	181	3	:	:	PUNCT
fnp-3804	181	4	improved	improve	VERB
fnp-3804	181	5	(	(	PUNCT
fnp-3804	181	6	histo)molecular	histo)molecular	PROPN
fnp-3804	181	7	grading	grading	NOUN
fnp-3804	181	8	of	of	ADP
fnp-3804	181	9	meningiomas	meningiomas	PROPN
fnp-3804	181	10	12	12	NUM
fnp-3804	181	11	-	-	SYM
fnp-3804	181	12	14	14	NUM
fnp-3804	181	13	until	until	ADP
fnp-3804	181	14	recently	recently	ADV
fnp-3804	181	15	,	,	PUNCT
fnp-3804	181	16	the	the	DET
fnp-3804	181	17	diagnosis	diagnosis	NOUN
fnp-3804	181	18	who	who	PRON
fnp-3804	181	19	grade	grade	NOUN
fnp-3804	181	20	ii	ii	PROPN
fnp-3804	181	21	meningiomas	meningioma	NOUN
fnp-3804	181	22	was	be	AUX
fnp-3804	181	23	based	base	VERB
fnp-3804	181	24	on	on	ADP
fnp-3804	181	25	the	the	DET
fnp-3804	181	26	presence	presence	NOUN
fnp-3804	181	27	of	of	ADP
fnp-3804	181	28	increased	increase	VERB
fnp-3804	181	29	mitotic	mitotic	ADJ
fnp-3804	181	30	activity	activity	NOUN
fnp-3804	181	31	,	,	PUNCT
fnp-3804	181	32	brain	brain	NOUN
fnp-3804	181	33	invasion	invasion	NOUN
fnp-3804	181	34	,	,	PUNCT
fnp-3804	181	35	presence	presence	NOUN
fnp-3804	181	36	/	/	SYM
fnp-3804	181	37	absence	absence	NOUN
fnp-3804	181	38	of	of	ADP
fnp-3804	181	39	three	three	NUM
fnp-3804	181	40	or	or	CCONJ
fnp-3804	181	41	more	more	ADJ
fnp-3804	181	42	of	of	ADP
fnp-3804	181	43	the	the	DET
fnp-3804	181	44	following	follow	VERB
fnp-3804	181	45	features	feature	NOUN
fnp-3804	181	46	:	:	PUNCT
fnp-3804	181	47	high	high	ADJ
fnp-3804	181	48	cellularity	cellularity	NOUN
fnp-3804	181	49	,	,	PUNCT
fnp-3804	181	50	small	small	ADJ
fnp-3804	181	51	cells	cell	NOUN
fnp-3804	181	52	with	with	ADP
fnp-3804	181	53	a	a	DET
fnp-3804	181	54	high	high	ADJ
fnp-3804	181	55	nucleus	nucleus	NOUN
fnp-3804	181	56	:	:	PUNCT
fnp-3804	181	57	cytoplasm	cytoplasm	ADJ
fnp-3804	181	58	ratio	ratio	NOUN
fnp-3804	181	59	,	,	PUNCT
fnp-3804	181	60	prominent	prominent	ADJ
fnp-3804	181	61	nucleoli	nucleolus	NOUN
fnp-3804	181	62	,	,	PUNCT
fnp-3804	181	63	patternless	patternless	NOUN
fnp-3804	181	64	/	/	SYM
fnp-3804	181	65	sheet	sheet	NOUN
fnp-3804	181	66	-	-	PUNCT
fnp-3804	181	67	like	like	ADJ
fnp-3804	181	68	growth	growth	NOUN
fnp-3804	181	69	,	,	PUNCT
fnp-3804	181	70	and	and	CCONJ
fnp-3804	181	71	foci	focus	NOUN
fnp-3804	181	72	of	of	ADP
fnp-3804	181	73	necrosis	necrosis	NOUN
fnp-3804	181	74	.	.	PUNCT
fnp-3804	182	1	furthermore	furthermore	ADV
fnp-3804	182	2	,	,	PUNCT
fnp-3804	182	3	particular	particular	ADJ
fnp-3804	182	4	histological	histological	ADJ
fnp-3804	182	5	phenotypes	phenotype	NOUN
fnp-3804	182	6	were	be	AUX
fnp-3804	182	7	used	use	VERB
fnp-3804	182	8	to	to	PART
fnp-3804	182	9	assign	assign	VERB
fnp-3804	182	10	a	a	DET
fnp-3804	182	11	who	who	PRON
fnp-3804	182	12	grade	grade	NOUN
fnp-3804	182	13	ii	ii	PROPN
fnp-3804	182	14	(	(	PUNCT
fnp-3804	182	15	clear	clear	ADJ
fnp-3804	182	16	cell	cell	NOUN
fnp-3804	182	17	,	,	PUNCT
fnp-3804	182	18	chordoid	chordoid	NOUN
fnp-3804	182	19	)	)	PUNCT
fnp-3804	182	20	or	or	CCONJ
fnp-3804	182	21	who	who	PRON
fnp-3804	182	22	grade	grade	VERB
fnp-3804	182	23	iii	iii	X
fnp-3804	182	24	(	(	PUNCT
fnp-3804	182	25	rhabdoid	rhabdoid	NOUN
fnp-3804	182	26	,	,	PUNCT
fnp-3804	182	27	papillary	papillary	NOUN
fnp-3804	182	28	)	)	PUNCT
fnp-3804	182	29	to	to	ADP
fnp-3804	182	30	meningiomas	meningioma	NOUN
fnp-3804	182	31	,	,	PUNCT
fnp-3804	182	32	while	while	SCONJ
fnp-3804	182	33	very	very	ADV
fnp-3804	182	34	high	high	ADJ
fnp-3804	182	35	mitotic	mitotic	ADJ
fnp-3804	182	36	activity	activity	NOUN
fnp-3804	182	37	and/or	and/or	CCONJ
fnp-3804	182	38	overtly	overtly	ADV
fnp-3804	182	39	malignant	malignant	ADJ
fnp-3804	182	40	cytomorphology	cytomorphology	NOUN
fnp-3804	182	41	were	be	AUX
fnp-3804	182	42	considered	consider	VERB
fnp-3804	182	43	as	as	ADV
fnp-3804	182	44	sufficient	sufficient	ADJ
fnp-3804	182	45	for	for	ADP
fnp-3804	182	46	the	the	DET
fnp-3804	182	47	diagnosis	diagnosis	NOUN
fnp-3804	182	48	of	of	ADP
fnp-3804	182	49	malignant	malignant	ADJ
fnp-3804	182	50	/	/	SYM
fnp-3804	182	51	anaplastic	anaplastic	ADJ
fnp-3804	182	52	meningioma	meningioma	NOUN
fnp-3804	182	53	(	(	PUNCT
fnp-3804	182	54	who	who	PRON
fnp-3804	182	55	grade	grade	NOUN
fnp-3804	182	56	iii	iii	NOUN
fnp-3804	182	57	)	)	PUNCT
fnp-3804	182	58	as	as	ADV
fnp-3804	182	59	well	well	ADV
fnp-3804	182	60	.	.	PUNCT
fnp-3804	183	1	however	however	ADV
fnp-3804	183	2	,	,	PUNCT
fnp-3804	183	3	the	the	DET
fnp-3804	183	4	prognostic	prognostic	ADJ
fnp-3804	183	5	meaning	meaning	NOUN
fnp-3804	183	6	of	of	ADP
fnp-3804	183	7	this	this	DET
fnp-3804	183	8	histology	histology	NOUN
fnp-3804	183	9	-	-	PUNCT
fnp-3804	183	10	based	base	VERB
fnp-3804	183	11	grading	grading	NOUN
fnp-3804	183	12	system	system	NOUN
fnp-3804	183	13	was	be	AUX
fnp-3804	183	14	suboptimal	suboptimal	ADJ
fnp-3804	183	15	,	,	PUNCT
fnp-3804	183	16	and	and	CCONJ
fnp-3804	183	17	it	it	PRON
fnp-3804	183	18	became	become	VERB
fnp-3804	183	19	increasingly	increasingly	ADV
fnp-3804	183	20	clear	clear	ADJ
fnp-3804	183	21	that	that	SCONJ
fnp-3804	183	22	molecular	molecular	ADJ
fnp-3804	183	23	data	datum	NOUN
fnp-3804	183	24	can	can	AUX
fnp-3804	183	25	be	be	AUX
fnp-3804	183	26	used	use	VERB
fnp-3804	183	27	to	to	PART
fnp-3804	183	28	refine	refine	VERB
fnp-3804	183	29	grading	grade	VERB
fnp-3804	183	30	of	of	ADP
fnp-3804	183	31	these	these	DET
fnp-3804	183	32	tumors	tumor	NOUN
fnp-3804	183	33	.	.	PUNCT
fnp-3804	184	1	indeed	indeed	ADV
fnp-3804	184	2	,	,	PUNCT
fnp-3804	184	3	in	in	ADP
fnp-3804	184	4	the	the	PRON
fnp-3804	184	5	who	who	PRON
fnp-3804	184	6	cns5	cns5	PROPN
fnp-3804	184	7	classification	classification	NOUN
fnp-3804	184	8	,	,	PUNCT
fnp-3804	184	9	presence	presence	NOUN
fnp-3804	184	10	of	of	ADP
fnp-3804	184	11	tert	tert	NOUN
fnp-3804	184	12	promoter	promoter	NOUN
fnp-3804	184	13	mutation	mutation	NOUN
fnp-3804	184	14	and/or	and/or	CCONJ
fnp-3804	184	15	homozygous	homozygous	ADJ
fnp-3804	184	16	cdkn2a	cdkn2a	PROPN
fnp-3804	184	17	and/or	and/or	CCONJ
fnp-3804	184	18	cdkn2b	cdkn2b	NOUN
fnp-3804	184	19	deletion	deletion	NOUN
fnp-3804	184	20	are	be	AUX
fnp-3804	184	21	now	now	ADV
fnp-3804	184	22	listed	list	VERB
fnp-3804	184	23	as	as	ADP
fnp-3804	184	24	criteria	criterion	NOUN
fnp-3804	184	25	for	for	ADP
fnp-3804	184	26	meningioma	meningioma	NOUN
fnp-3804	184	27	,	,	PUNCT
fnp-3804	184	28	cns	cns	PROPN
fnp-3804	184	29	who	who	PRON
fnp-3804	184	30	grade	grade	VERB
fnp-3804	184	31	3	3	NUM
fnp-3804	184	32	.	.	PUNCT
fnp-3804	185	1	furthermore	furthermore	ADV
fnp-3804	185	2	,	,	PUNCT
fnp-3804	185	3	in	in	ADP
fnp-3804	185	4	this	this	DET
fnp-3804	185	5	new	new	ADJ
fnp-3804	185	6	classification	classification	NOUN
fnp-3804	185	7	,	,	PUNCT
fnp-3804	185	8	the	the	DET
fnp-3804	185	9	rhabdoid	rhabdoid	NOUN
fnp-3804	185	10	and	and	CCONJ
fnp-3804	185	11	papillary	papillary	ADJ
fnp-3804	185	12	phenotypes	phenotype	NOUN
fnp-3804	185	13	are	be	AUX
fnp-3804	185	14	no	no	ADV
fnp-3804	185	15	longer	long	ADV
fnp-3804	185	16	considered	consider	VERB
fnp-3804	185	17	as	as	ADP
fnp-3804	185	18	cns	cns	PROPN
fnp-3804	185	19	who	who	PRON
fnp-3804	185	20	grade	grade	NOUN
fnp-3804	185	21	3	3	NUM
fnp-3804	185	22	based	base	VERB
fnp-3804	185	23	on	on	ADP
fnp-3804	185	24	their	their	PRON
fnp-3804	185	25	histological	histological	ADJ
fnp-3804	185	26	phenotype	phenotype	NOUN
fnp-3804	185	27	alone	alone	ADV
fnp-3804	185	28	1,34	1,34	NUM
fnp-3804	185	29	.	.	PUNCT
fnp-3804	186	1	nassiri	nassiri	PROPN
fnp-3804	186	2	f	f	PROPN
fnp-3804	186	3	et	et	PROPN
fnp-3804	186	4	al	al	PROPN
fnp-3804	186	5	.	.	PUNCT
fnp-3804	187	1	(	(	PUNCT
fnp-3804	187	2	with	with	ADP
fnp-3804	187	3	aldape	aldape	PROPN
fnp-3804	187	4	k	k	PROPN
fnp-3804	187	5	and	and	CCONJ
fnp-3804	187	6	zadeh	zadeh	PROPN
fnp-3804	187	7	g	g	PROPN
fnp-3804	187	8	as	as	ADP
fnp-3804	187	9	supervising	supervise	VERB
fnp-3804	187	10	authors	author	NOUN
fnp-3804	187	11	)	)	PUNCT
fnp-3804	187	12	published	publish	VERB
fnp-3804	187	13	a	a	DET
fnp-3804	187	14	paper	paper	NOUN
fnp-3804	187	15	in	in	ADP
fnp-3804	187	16	nature	nature	NOUN
fnp-3804	187	17	providing	provide	VERB
fnp-3804	187	18	a	a	DET
fnp-3804	187	19	wealth	wealth	NOUN
fnp-3804	187	20	of	of	ADP
fnp-3804	187	21	matched	match	VERB
fnp-3804	187	22	multidimensional	multidimensional	ADJ
fnp-3804	187	23	bulk	bulk	NOUN
fnp-3804	187	24	and	and	CCONJ
fnp-3804	187	25	single	single	ADJ
fnp-3804	187	26	-	-	PUNCT
fnp-3804	187	27	cell	cell	NOUN
fnp-3804	187	28	molecular	molecular	ADJ
fnp-3804	187	29	and	and	CCONJ
fnp-3804	187	30	clinical	clinical	ADJ
fnp-3804	187	31	data	datum	NOUN
fnp-3804	187	32	on	on	ADP
fnp-3804	187	33	a	a	DET
fnp-3804	187	34	large	large	ADJ
fnp-3804	187	35	cohort	cohort	NOUN
fnp-3804	187	36	of	of	ADP
fnp-3804	187	37	meningiomas	meningioma	NOUN
fnp-3804	187	38	,	,	PUNCT
fnp-3804	187	39	enriched	enrich	VERB
fnp-3804	187	40	for	for	ADP
fnp-3804	187	41	the	the	DET
fnp-3804	187	42	higher	high	ADJ
fnp-3804	187	43	-	-	PUNCT
fnp-3804	187	44	grade	grade	NOUN
fnp-3804	187	45	tumors	tumor	NOUN
fnp-3804	187	46	according	accord	VERB
fnp-3804	187	47	to	to	ADP
fnp-3804	187	48	who	who	PRON
fnp-3804	187	49	2016	2016	NUM
fnp-3804	187	50	criteria	criterion	NOUN
fnp-3804	187	51	12	12	NUM
fnp-3804	187	52	.	.	PUNCT
fnp-3804	188	1	unsupervised	unsupervised	ADJ
fnp-3804	188	2	sample	sample	NOUN
fnp-3804	188	3	-	-	PUNCT
fnp-3804	188	4	wise	wise	ADJ
fnp-3804	188	5	clustering	clustering	NOUN
fnp-3804	188	6	of	of	ADP
fnp-3804	188	7	gene	gene	NOUN
fnp-3804	188	8	-	-	PUNCT
fnp-3804	188	9	level	level	NOUN
fnp-3804	188	10	somatic	somatic	ADJ
fnp-3804	188	11	copy	copy	NOUN
fnp-3804	188	12	-	-	PUNCT
fnp-3804	188	13	number	number	NOUN
fnp-3804	188	14	alterations	alteration	NOUN
fnp-3804	188	15	(	(	PUNCT
fnp-3804	188	16	cnas	cnas	PROPN
fnp-3804	188	17	)	)	PUNCT
fnp-3804	188	18	,	,	PUNCT
fnp-3804	188	19	dna	dna	PROPN
fnp-3804	188	20	methylome	methylome	PROPN
fnp-3804	188	21	,	,	PUNCT
fnp-3804	188	22	and	and	CCONJ
fnp-3804	188	23	transcriptome	transcriptome	ADJ
fnp-3804	188	24	data	datum	NOUN
fnp-3804	188	25	in	in	ADP
fnp-3804	188	26	isolation	isolation	NOUN
fnp-3804	188	27	revealed	reveal	VERB
fnp-3804	188	28	six	six	NUM
fnp-3804	188	29	stable	stable	ADJ
fnp-3804	188	30	subgroups	subgroup	NOUN
fnp-3804	188	31	for	for	ADP
fnp-3804	188	32	each	each	DET
fnp-3804	188	33	datatype	datatype	NOUN
fnp-3804	188	34	with	with	ADP
fnp-3804	188	35	clinically	clinically	ADV
fnp-3804	188	36	relevant	relevant	ADJ
fnp-3804	188	37	and	and	CCONJ
fnp-3804	188	38	significant	significant	ADJ
fnp-3804	188	39	differences	difference	NOUN
fnp-3804	188	40	in	in	ADP
fnp-3804	188	41	outcome	outcome	NOUN
fnp-3804	188	42	.	.	PUNCT
fnp-3804	189	1	additional	additional	ADJ
fnp-3804	189	2	(	(	PUNCT
fnp-3804	189	3	second	second	ADJ
fnp-3804	189	4	-	-	PUNCT
fnp-3804	189	5	order	order	NOUN
fnp-3804	189	6	)	)	PUNCT
fnp-3804	189	7	clustering	clustering	NOUN
fnp-3804	189	8	revealed	reveal	VERB
fnp-3804	189	9	four	four	NUM
fnp-3804	189	10	stable	stable	ADJ
fnp-3804	189	11	molecular	molecular	ADJ
fnp-3804	189	12	groups	group	NOUN
fnp-3804	189	13	(	(	PUNCT
fnp-3804	189	14	mg1	mg1	PROPN
fnp-3804	189	15	–	–	PUNCT
fnp-3804	189	16	mg4	mg4	PROPN
fnp-3804	189	17	)	)	PUNCT
fnp-3804	189	18	without	without	ADP
fnp-3804	189	19	a	a	DET
fnp-3804	189	20	clear	clear	ADJ
fnp-3804	189	21	one	one	NUM
fnp-3804	189	22	-	-	PUNCT
fnp-3804	189	23	to	to	ADP
fnp-3804	189	24	-	-	PUNCT
fnp-3804	189	25	one	one	NUM
fnp-3804	189	26	relationship	relationship	NOUN
fnp-3804	189	27	between	between	ADP
fnp-3804	189	28	molecular	molecular	ADJ
fnp-3804	189	29	group	group	NOUN
fnp-3804	189	30	and	and	CCONJ
fnp-3804	189	31	who	who	PRON
fnp-3804	189	32	grade	grade	VERB
fnp-3804	189	33	.	.	PUNCT
fnp-3804	190	1	classification	classification	NOUN
fnp-3804	190	2	by	by	ADP
fnp-3804	190	3	molecular	molecular	ADJ
fnp-3804	190	4	groups	group	NOUN
fnp-3804	190	5	was	be	AUX
fnp-3804	190	6	independently	independently	ADV
fnp-3804	190	7	associated	associate	VERB
fnp-3804	190	8	with	with	ADP
fnp-3804	190	9	recurrence	recurrence	NOUN
fnp-3804	190	10	-	-	PUNCT
fnp-3804	190	11	free	free	ADJ
fnp-3804	190	12	survival	survival	NOUN
fnp-3804	190	13	as	as	SCONJ
fnp-3804	190	14	assessed	assess	VERB
fnp-3804	190	15	by	by	ADP
fnp-3804	190	16	multivariable	multivariable	ADJ
fnp-3804	190	17	cox	cox	PROPN
fnp-3804	190	18	regression	regression	PROPN
fnp-3804	190	19	,	,	PUNCT
fnp-3804	190	20	even	even	ADV
fnp-3804	190	21	after	after	ADP
fnp-3804	190	22	accounting	account	VERB
fnp-3804	190	23	for	for	ADP
fnp-3804	190	24	known	know	VERB
fnp-3804	190	25	prognostic	prognostic	ADJ
fnp-3804	190	26	clinical	clinical	ADJ
fnp-3804	190	27	factors	factor	NOUN
fnp-3804	190	28	.	.	PUNCT
fnp-3804	191	1	mg3	mg3	PROPN
fnp-3804	191	2	and	and	CCONJ
fnp-3804	191	3	mg4	mg4	PROPN
fnp-3804	191	4	tumors	tumor	NOUN
fnp-3804	191	5	(	(	PUNCT
fnp-3804	191	6	carrying	carry	VERB
fnp-3804	191	7	the	the	DET
fnp-3804	191	8	most	most	ADV
fnp-3804	191	9	unfavorable	unfavorable	ADJ
fnp-3804	191	10	outcomes	outcome	NOUN
fnp-3804	191	11	)	)	PUNCT
fnp-3804	191	12	were	be	AUX
fnp-3804	191	13	found	find	VERB
fnp-3804	191	14	to	to	PART
fnp-3804	191	15	be	be	AUX
fnp-3804	191	16	high	high	ADJ
fnp-3804	191	17	-	-	PUNCT
fnp-3804	191	18	aneuploidy	aneuploidy	ADJ
fnp-3804	191	19	tumors	tumor	NOUN
fnp-3804	191	20	with	with	ADP
fnp-3804	191	21	losses	loss	NOUN
fnp-3804	191	22	in	in	ADP
fnp-3804	191	23	chromosomes	chromosome	NOUN
fnp-3804	191	24	22q	22q	NOUN
fnp-3804	191	25	,	,	PUNCT
fnp-3804	191	26	1p	1p	NUM
fnp-3804	191	27	,	,	PUNCT
fnp-3804	191	28	6q	6q	NOUN
fnp-3804	191	29	,	,	PUNCT
fnp-3804	191	30	14	14	NUM
fnp-3804	191	31	,	,	PUNCT
fnp-3804	191	32	and	and	CCONJ
fnp-3804	191	33	18	18	NUM
fnp-3804	191	34	.	.	PUNCT
fnp-3804	192	1	in	in	ADP
fnp-3804	192	2	addition	addition	NOUN
fnp-3804	192	3	,	,	PUNCT
fnp-3804	192	4	mg4	mg4	PROPN
fnp-3804	192	5	meningiomas	meningiomas	PROPN
fnp-3804	192	6	showed	show	VERB
fnp-3804	192	7	a	a	DET
fnp-3804	192	8	gain	gain	NOUN
fnp-3804	192	9	of	of	ADP
fnp-3804	192	10	chromosome	chromosome	NOUN
fnp-3804	192	11	1q	1q	NOUN
fnp-3804	192	12	and	and	CCONJ
fnp-3804	192	13	a	a	DET
fnp-3804	192	14	loss	loss	NOUN
fnp-3804	192	15	of	of	ADP
fnp-3804	192	16	chromosome	chromosome	NOUN
fnp-3804	192	17	10	10	NUM
fnp-3804	192	18	.	.	PUNCT
fnp-3804	193	1	such	such	ADJ
fnp-3804	193	2	findings	finding	NOUN
fnp-3804	193	3	have	have	VERB
fnp-3804	193	4	the	the	DET
fnp-3804	193	5	potential	potential	NOUN
fnp-3804	193	6	to	to	PART
fnp-3804	193	7	supersede	supersede	VERB
fnp-3804	193	8	existing	exist	VERB
fnp-3804	193	9	molecular	molecular	ADJ
fnp-3804	193	10	and	and	CCONJ
fnp-3804	193	11	clinically	clinically	ADV
fnp-3804	193	12	used	use	VERB
fnp-3804	193	13	classifications	classification	NOUN
fnp-3804	193	14	and	and	CCONJ
fnp-3804	193	15	grading	grade	VERB
fnp-3804	193	16	schemes	scheme	NOUN
fnp-3804	193	17	.	.	PUNCT
fnp-3804	194	1	indeed	indeed	ADV
fnp-3804	194	2	,	,	PUNCT
fnp-3804	194	3	two	two	NUM
fnp-3804	194	4	studies	study	NOUN
fnp-3804	194	5	published	publish	VERB
fnp-3804	194	6	in	in	ADP
fnp-3804	194	7	2021	2021	NUM
fnp-3804	194	8	show	show	VERB
fnp-3804	194	9	that	that	DET
fnp-3804	194	10	prognostication	prognostication	NOUN
fnp-3804	194	11	for	for	SCONJ
fnp-3804	194	12	patients	patient	NOUN
fnp-3804	194	13	with	with	ADP
fnp-3804	194	14	meningioma	meningioma	NOUN
fnp-3804	194	15	can	can	AUX
fnp-3804	194	16	be	be	AUX
fnp-3804	194	17	improved	improve	VERB
fnp-3804	194	18	by	by	ADP
fnp-3804	194	19	taking	take	VERB
fnp-3804	194	20	particular	particular	ADJ
fnp-3804	194	21	copy	copy	NOUN
fnp-3804	194	22	number	number	NOUN
fnp-3804	194	23	variations	variation	NOUN
fnp-3804	194	24	(	(	PUNCT
fnp-3804	194	25	cnvs	cnvs	NOUN
fnp-3804	194	26	)	)	PUNCT
fnp-3804	194	27	into	into	ADP
fnp-3804	194	28	account	account	NOUN
fnp-3804	194	29	(	(	PUNCT
fnp-3804	194	30	figure	figure	NOUN
fnp-3804	194	31	2	2	NUM
fnp-3804	194	32	)	)	PUNCT
fnp-3804	194	33	.	.	PUNCT
fnp-3804	195	1	driver	driver	NOUN
fnp-3804	195	2	j	j	PROPN
fnp-3804	195	3	et	et	PROPN
fnp-3804	195	4	al	al	PROPN
fnp-3804	195	5	.	.	PUNCT
fnp-3804	196	1	(	(	PUNCT
fnp-3804	196	2	corresponding	correspond	VERB
fnp-3804	196	3	authors	author	NOUN
fnp-3804	196	4	bi	bi	NOUN
fnp-3804	196	5	wl	wl	PROPN
fnp-3804	196	6	and	and	CCONJ
fnp-3804	196	7	santagata	santagata	VERB
fnp-3804	196	8	s	s	VERB
fnp-3804	196	9	)	)	PUNCT
fnp-3804	196	10	published	publish	VERB
fnp-3804	196	11	a	a	DET
fnp-3804	196	12	paper	paper	NOUN
fnp-3804	196	13	in	in	ADP
fnp-3804	196	14	neuro	neuro	NOUN
fnp-3804	196	15	-	-	PUNCT
fnp-3804	196	16	oncology	oncology	NOUN
fnp-3804	196	17	evaluating	evaluating	NOUN
fnp-3804	196	18	whether	whether	SCONJ
fnp-3804	196	19	the	the	DET
fnp-3804	196	20	use	use	NOUN
fnp-3804	196	21	of	of	ADP
fnp-3804	196	22	chromosomal	chromosomal	ADJ
fnp-3804	196	23	copy	copy	NOUN
fnp-3804	196	24	-	-	PUNCT
fnp-3804	196	25	number	number	NOUN
fnp-3804	196	26	data	datum	NOUN
fnp-3804	196	27	provided	provide	VERB
fnp-3804	196	28	more	more	ADV
fnp-3804	196	29	accurate	accurate	ADJ
fnp-3804	196	30	prediction	prediction	NOUN
fnp-3804	196	31	of	of	ADP
fnp-3804	196	32	time	time	NOUN
fnp-3804	196	33	to	to	PART
fnp-3804	196	34	recurrence	recurrence	VERB
fnp-3804	196	35	for	for	ADP
fnp-3804	196	36	patients	patient	NOUN
fnp-3804	196	37	with	with	ADP
fnp-3804	196	38	meningioma	meningioma	NOUN
fnp-3804	196	39	than	than	ADP
fnp-3804	196	40	the	the	DET
fnp-3804	196	41	traditional	traditional	ADJ
fnp-3804	196	42	who	who	PRON
fnp-3804	196	43	grades	grade	VERB
fnp-3804	196	44	14	14	NUM
fnp-3804	196	45	.	.	PUNCT
fnp-3804	197	1	their	their	PRON
fnp-3804	197	2	discovery	discovery	NOUN
fnp-3804	197	3	cohort	cohort	NOUN
fnp-3804	197	4	consisted	consist	VERB
fnp-3804	197	5	of	of	ADP
fnp-3804	197	6	527	527	NUM
fnp-3804	197	7	patients	patient	NOUN
fnp-3804	197	8	diagnosed	diagnose	VERB
fnp-3804	197	9	with	with	ADP
fnp-3804	197	10	meningioma	meningioma	NOUN
fnp-3804	197	11	,	,	PUNCT
fnp-3804	197	12	and	and	CCONJ
fnp-3804	197	13	two	two	NUM
fnp-3804	197	14	independent	independent	ADJ
fnp-3804	197	15	cohorts	cohort	NOUN
fnp-3804	197	16	of	of	ADP
fnp-3804	197	17	172	172	NUM
fnp-3804	197	18	meningioma	meningioma	NOUN
fnp-3804	197	19	patients	patient	NOUN
fnp-3804	197	20	were	be	AUX
fnp-3804	197	21	used	use	VERB
fnp-3804	197	22	for	for	ADP
fnp-3804	197	23	validation	validation	NOUN
fnp-3804	197	24	of	of	ADP
fnp-3804	197	25	the	the	DET
fnp-3804	197	26	findings	finding	NOUN
fnp-3804	197	27	.	.	PUNCT
fnp-3804	198	1	based	base	VERB
fnp-3804	198	2	on	on	ADP
fnp-3804	198	3	mitotic	mitotic	ADJ
fnp-3804	198	4	count	count	NOUN
fnp-3804	198	5	and	and	CCONJ
fnp-3804	198	6	the	the	DET
fnp-3804	198	7	presence	presence	NOUN
fnp-3804	198	8	/	/	SYM
fnp-3804	198	9	absence	absence	NOUN
fnp-3804	198	10	of	of	ADP
fnp-3804	198	11	the	the	DET
fnp-3804	198	12	loss	loss	NOUN
fnp-3804	198	13	of	of	ADP
fnp-3804	198	14	(	(	PUNCT
fnp-3804	198	15	arms	arm	NOUN
fnp-3804	198	16	of	of	ADP
fnp-3804	198	17	)	)	PUNCT
fnp-3804	198	18	particular	particular	ADJ
fnp-3804	198	19	chromosomes	chromosome	NOUN
fnp-3804	198	20	(	(	PUNCT
fnp-3804	198	21	1p	1p	NUM
fnp-3804	198	22	,	,	PUNCT
fnp-3804	198	23	3p	3p	NUM
fnp-3804	198	24	,	,	PUNCT
fnp-3804	198	25	4	4	NUM
fnp-3804	198	26	,	,	PUNCT
fnp-3804	198	27	6	6	NUM
fnp-3804	198	28	,	,	PUNCT
fnp-3804	198	29	10	10	NUM
fnp-3804	198	30	,	,	PUNCT
fnp-3804	198	31	14q	14q	NUM
fnp-3804	198	32	,	,	PUNCT
fnp-3804	198	33	18	18	NUM
fnp-3804	198	34	,	,	PUNCT
fnp-3804	198	35	19	19	NUM
fnp-3804	198	36	)	)	PUNCT
fnp-3804	198	37	,	,	PUNCT
fnp-3804	198	38	and	and	CCONJ
fnp-3804	198	39	of	of	ADP
fnp-3804	198	40	homozygous	homozygous	ADJ
fnp-3804	198	41	deletion	deletion	NOUN
fnp-3804	198	42	of	of	ADP
fnp-3804	198	43	cdkn2a	cdkn2a	PROPN
fnp-3804	198	44	the	the	DET
fnp-3804	198	45	authors	author	NOUN
fnp-3804	198	46	developed	develop	VERB
fnp-3804	198	47	a	a	DET
fnp-3804	198	48	scheme	scheme	NOUN
fnp-3804	198	49	with	with	ADP
fnp-3804	198	50	three	three	NUM
fnp-3804	198	51	integrated	integrate	VERB
fnp-3804	198	52	grades	grade	NOUN
fnp-3804	198	53	(	(	PUNCT
fnp-3804	198	54	1	1	NUM
fnp-3804	198	55	-	-	SYM
fnp-3804	198	56	3	3	NUM
fnp-3804	198	57	)	)	PUNCT
fnp-3804	198	58	.	.	PUNCT
fnp-3804	199	1	this	this	DET
fnp-3804	199	2	grading	grade	VERB
fnp-3804	199	3	approach	approach	NOUN
fnp-3804	199	4	was	be	AUX
fnp-3804	199	5	found	find	VERB
fnp-3804	199	6	to	to	PART
fnp-3804	199	7	more	more	ADV
fnp-3804	199	8	accurately	accurately	ADV
fnp-3804	199	9	identify	identify	VERB
fnp-3804	199	10	meningioma	meningioma	NOUN
fnp-3804	199	11	patients	patient	NOUN
fnp-3804	199	12	at	at	ADP
fnp-3804	199	13	risk	risk	NOUN
fnp-3804	199	14	for	for	ADP
fnp-3804	199	15	recurrence	recurrence	NOUN
fnp-3804	199	16	than	than	ADP
fnp-3804	199	17	the	the	DET
fnp-3804	199	18	traditional	traditional	ADJ
fnp-3804	199	19	who	who	PRON
fnp-3804	199	20	grading	grade	VERB
fnp-3804	199	21	system	system	NOUN
fnp-3804	199	22	.	.	PUNCT
fnp-3804	200	1	figure	figure	NOUN
fnp-3804	200	2	2	2	NUM
fnp-3804	200	3	.	.	NOUN
fnp-3804	200	4	assessment	assessment	NOUN
fnp-3804	200	5	of	of	ADP
fnp-3804	200	6	chromosomal	chromosomal	ADJ
fnp-3804	200	7	copy	copy	NOUN
fnp-3804	200	8	number	number	NOUN
fnp-3804	200	9	aberrations	aberration	NOUN
fnp-3804	200	10	for	for	ADP
fnp-3804	200	11	improved	improved	ADJ
fnp-3804	200	12	grading	grading	NOUN
fnp-3804	200	13	of	of	ADP
fnp-3804	200	14	meningiomas.both	meningiomas.both	PROPN
fnp-3804	200	15	in	in	ADP
fnp-3804	200	16	the	the	DET
fnp-3804	200	17	study	study	NOUN
fnp-3804	200	18	by	by	ADP
fnp-3804	200	19	driver	driver	PROPN
fnp-3804	200	20	j	j	PROPN
fnp-3804	200	21	et	et	PROPN
fnp-3804	200	22	al	al	PROPN
fnp-3804	200	23	.	.	PROPN
fnp-3804	200	24	14	14	NUM
fnp-3804	200	25	and	and	CCONJ
fnp-3804	200	26	by	by	ADP
fnp-3804	200	27	maas	maas	PROPN
fnp-3804	200	28	sln	sln	PROPN
fnp-3804	200	29	et	et	PROPN
fnp-3804	200	30	al	al	PROPN
fnp-3804	200	31	.	.	PROPN
fnp-3804	200	32	13	13	NUM
fnp-3804	200	33	the	the	DET
fnp-3804	200	34	presence	presence	NOUN
fnp-3804	200	35	/	/	SYM
fnp-3804	200	36	absence	absence	NOUN
fnp-3804	200	37	of	of	ADP
fnp-3804	200	38	particular	particular	ADJ
fnp-3804	200	39	chromosomal	chromosomal	ADJ
fnp-3804	200	40	losses	loss	NOUN
fnp-3804	200	41	is	be	AUX
fnp-3804	200	42	used	use	VERB
fnp-3804	200	43	for	for	ADP
fnp-3804	200	44	assessment	assessment	NOUN
fnp-3804	200	45	of	of	ADP
fnp-3804	200	46	prognosis	prognosis	NOUN
fnp-3804	200	47	of	of	ADP
fnp-3804	200	48	meningiomas	meningioma	NOUN
fnp-3804	200	49	.	.	PUNCT
fnp-3804	201	1	in	in	ADP
fnp-3804	201	2	the	the	DET
fnp-3804	201	3	‘	'	PUNCT
fnp-3804	201	4	driver	driver	NOUN
fnp-3804	201	5	approach	approach	NOUN
fnp-3804	201	6	’	'	PUNCT
fnp-3804	201	7	,	,	PUNCT
fnp-3804	201	8	this	this	PRON
fnp-3804	201	9	is	be	AUX
fnp-3804	201	10	combined	combine	VERB
fnp-3804	201	11	with	with	ADP
fnp-3804	201	12	information	information	NOUN
fnp-3804	201	13	on	on	ADP
fnp-3804	201	14	cdkn2a	cdkn2a	PROPN
fnp-3804	201	15	/	/	SYM
fnp-3804	201	16	b	b	PROPN
fnp-3804	201	17	status	status	NOUN
fnp-3804	201	18	and	and	CCONJ
fnp-3804	201	19	number	number	NOUN
fnp-3804	201	20	of	of	ADP
fnp-3804	201	21	mitoses	mitose	NOUN
fnp-3804	201	22	,	,	PUNCT
fnp-3804	201	23	while	while	SCONJ
fnp-3804	201	24	in	in	ADP
fnp-3804	201	25	the	the	DET
fnp-3804	201	26	‘	'	PUNCT
fnp-3804	201	27	maas	maas	NOUN
fnp-3804	201	28	approach	approach	NOUN
fnp-3804	201	29	’	'	PUNCT
fnp-3804	201	30	the	the	DET
fnp-3804	201	31	grade	grade	NOUN
fnp-3804	201	32	as	as	ADP
fnp-3804	201	33	traditionally	traditionally	ADV
fnp-3804	201	34	assigned	assign	VERB
fnp-3804	201	35	based	base	VERB
fnp-3804	201	36	on	on	ADP
fnp-3804	201	37	histological	histological	ADJ
fnp-3804	201	38	features	feature	NOUN
fnp-3804	201	39	and	and	CCONJ
fnp-3804	201	40	the	the	DET
fnp-3804	201	41	suggested	suggest	VERB
fnp-3804	201	42	methylation	methylation	NOUN
fnp-3804	201	43	family	family	NOUN
fnp-3804	201	44	using	use	VERB
fnp-3804	201	45	the	the	DET
fnp-3804	201	46	meningioma	meningioma	NOUN
fnp-3804	201	47	classifier	classifier	NOUN
fnp-3804	201	48	(	(	PUNCT
fnp-3804	201	49	benign	benign	ADJ
fnp-3804	201	50	–	–	PUNCT
fnp-3804	201	51	intermediate	intermediate	ADJ
fnp-3804	201	52	–	–	PUNCT
fnp-3804	201	53	malignant	malignant	ADJ
fnp-3804	201	54	)	)	PUNCT
fnp-3804	201	55	are	be	AUX
fnp-3804	201	56	taken	take	VERB
fnp-3804	201	57	into	into	ADP
fnp-3804	201	58	account	account	NOUN
fnp-3804	201	59	as	as	ADV
fnp-3804	201	60	well	well	ADV
fnp-3804	201	61	.	.	PUNCT
fnp-3804	202	1	importantly	importantly	ADV
fnp-3804	202	2	,	,	PUNCT
fnp-3804	202	3	next	next	ADV
fnp-3804	202	4	to	to	ADP
fnp-3804	202	5	methylation	methylation	NOUN
fnp-3804	202	6	array	array	NOUN
fnp-3804	202	7	-	-	PUNCT
fnp-3804	202	8	based	base	VERB
fnp-3804	202	9	grading	grading	NOUN
fnp-3804	202	10	system	system	NOUN
fnp-3804	202	11	for	for	ADP
fnp-3804	202	12	meningiomas	meningioma	NOUN
fnp-3804	202	13	,	,	PUNCT
fnp-3804	202	14	the	the	DET
fnp-3804	202	15	study	study	NOUN
fnp-3804	202	16	of	of	ADP
fnp-3804	202	17	maas	maas	PROPN
fnp-3804	202	18	et	et	PROPN
fnp-3804	202	19	al	al	PROPN
fnp-3804	202	20	.	.	PROPN
fnp-3804	202	21	presents	present	VERB
fnp-3804	202	22	some	some	DET
fnp-3804	202	23	alternatives	alternative	NOUN
fnp-3804	202	24	for	for	ADP
fnp-3804	202	25	a	a	DET
fnp-3804	202	26	more	more	ADV
fnp-3804	202	27	stepwise	stepwise	ADJ
fnp-3804	202	28	approach	approach	NOUN
fnp-3804	202	29	for	for	ADP
fnp-3804	202	30	grading	grade	VERB
fnp-3804	202	31	of	of	ADP
fnp-3804	202	32	meningiomas	meningioma	NOUN
fnp-3804	202	33	,	,	PUNCT
fnp-3804	202	34	taking	take	VERB
fnp-3804	202	35	into	into	ADP
fnp-3804	202	36	account	account	NOUN
fnp-3804	202	37	that	that	SCONJ
fnp-3804	202	38	particular	particular	ADJ
fnp-3804	202	39	histological	histological	ADJ
fnp-3804	202	40	phenotypes	phenotype	NOUN
fnp-3804	202	41	(	(	PUNCT
fnp-3804	202	42	angiomatous	angiomatous	ADJ
fnp-3804	202	43	,	,	PUNCT
fnp-3804	202	44	psammomatous	psammomatous	ADJ
fnp-3804	202	45	,	,	PUNCT
fnp-3804	202	46	secretory	secretory	NOUN
fnp-3804	202	47	)	)	PUNCT
fnp-3804	202	48	are	be	AUX
fnp-3804	202	49	strongly	strongly	ADV
fnp-3804	202	50	associated	associate	VERB
fnp-3804	202	51	with	with	ADP
fnp-3804	202	52	cns	cns	PROPN
fnp-3804	202	53	who	who	PRON
fnp-3804	202	54	grade	grade	VERB
fnp-3804	202	55	1	1	NUM
fnp-3804	202	56	behavior	behavior	NOUN
fnp-3804	202	57	,	,	PUNCT
fnp-3804	202	58	while	while	SCONJ
fnp-3804	202	59	presence	presence	NOUN
fnp-3804	202	60	of	of	ADP
fnp-3804	202	61	tert	tert	NOUN
fnp-3804	202	62	promoter	promoter	NOUN
fnp-3804	202	63	mutation	mutation	NOUN
fnp-3804	202	64	and/or	and/or	CCONJ
fnp-3804	202	65	cdkn2a	cdkn2a	PROPN
fnp-3804	202	66	/	/	SYM
fnp-3804	202	67	b	b	NOUN
fnp-3804	202	68	loss	loss	NOUN
fnp-3804	202	69	indicate	indicate	VERB
fnp-3804	202	70	high	high	ADJ
fnp-3804	202	71	-	-	PUNCT
fnp-3804	202	72	risk	risk	NOUN
fnp-3804	202	73	tumors	tumor	NOUN
fnp-3804	202	74	.	.	PUNCT
fnp-3804	203	1	maas	maas	PROPN
fnp-3804	203	2	sln	sln	PROPN
fnp-3804	203	3	,	,	PUNCT
fnp-3804	203	4	stichel	stichel	PROPN
fnp-3804	203	5	d	d	PROPN
fnp-3804	203	6	,	,	PUNCT
fnp-3804	203	7	hielscher	hielscher	PROPN
fnp-3804	203	8	t	t	PROPN
fnp-3804	203	9	,	,	PUNCT
fnp-3804	203	10	sievers	sievers	PROPN
fnp-3804	203	11	p	p	PROPN
fnp-3804	203	12	et	et	PROPN
fnp-3804	203	13	al	al	PROPN
fnp-3804	203	14	.	.	PUNCT
fnp-3804	204	1	(	(	PUNCT
fnp-3804	204	2	supervisors	supervisor	NOUN
fnp-3804	204	3	von	von	PROPN
fnp-3804	204	4	deimling	deimle	VERB
fnp-3804	204	5	a	a	PRON
fnp-3804	204	6	and	and	CCONJ
fnp-3804	204	7	sahm	sahm	PROPN
fnp-3804	204	8	f	f	X
fnp-3804	204	9	)	)	PUNCT
fnp-3804	204	10	published	publish	VERB
fnp-3804	204	11	a	a	DET
fnp-3804	204	12	study	study	NOUN
fnp-3804	204	13	in	in	ADP
fnp-3804	204	14	the	the	DET
fnp-3804	204	15	journal	journal	NOUN
fnp-3804	204	16	clinical	clinical	ADJ
fnp-3804	204	17	oncology	oncology	NOUN
fnp-3804	204	18	in	in	ADP
fnp-3804	204	19	which	which	PRON
fnp-3804	204	20	dna	dna	PROPN
fnp-3804	204	21	methylation	methylation	NOUN
fnp-3804	204	22	profiling	profiling	NOUN
fnp-3804	204	23	and	and	CCONJ
fnp-3804	204	24	copy	copy	NOUN
fnp-3804	204	25	-	-	PUNCT
fnp-3804	204	26	number	number	NOUN
fnp-3804	204	27	information	information	NOUN
fnp-3804	204	28	were	be	AUX
fnp-3804	204	29	generated	generate	VERB
fnp-3804	204	30	for	for	ADP
fnp-3804	204	31	3,031	3,031	NUM
fnp-3804	204	32	meningiomas	meningioma	NOUN
fnp-3804	204	33	of	of	ADP
fnp-3804	204	34	2,868	2,868	NUM
fnp-3804	204	35	patients	patient	NOUN
fnp-3804	204	36	and	and	CCONJ
fnp-3804	204	37	mutation	mutation	NOUN
fnp-3804	204	38	data	datum	NOUN
fnp-3804	204	39	for	for	ADP
fnp-3804	204	40	858	858	NUM
fnp-3804	204	41	samples	sample	NOUN
fnp-3804	204	42	13	13	NUM
fnp-3804	204	43	.	.	PUNCT
fnp-3804	205	1	both	both	DET
fnp-3804	205	2	cnvand	cnvand	ADJ
fnp-3804	205	3	methylation	methylation	NOUN
fnp-3804	205	4	family	family	NOUN
fnp-3804	205	5	-	-	PUNCT
fnp-3804	205	6	based	base	VERB
fnp-3804	205	7	subgrouping	subgrouping	NOUN
fnp-3804	205	8	independently	independently	ADV
fnp-3804	205	9	resulted	result	VERB
fnp-3804	205	10	in	in	ADP
fnp-3804	205	11	increased	increase	VERB
fnp-3804	205	12	prediction	prediction	NOUN
fnp-3804	205	13	accuracy	accuracy	NOUN
fnp-3804	205	14	of	of	ADP
fnp-3804	205	15	risk	risk	NOUN
fnp-3804	205	16	of	of	ADP
fnp-3804	205	17	recurrence	recurrence	NOUN
fnp-3804	205	18	compared	compare	VERB
fnp-3804	205	19	with	with	ADP
fnp-3804	205	20	who	who	PRON
fnp-3804	205	21	grading	grade	VERB
fnp-3804	205	22	.	.	PUNCT
fnp-3804	206	1	prediction	prediction	NOUN
fnp-3804	206	2	power	power	NOUN
fnp-3804	206	3	for	for	ADP
fnp-3804	206	4	outcome	outcome	NOUN
fnp-3804	206	5	was	be	AUX
fnp-3804	206	6	assessed	assess	VERB
fnp-3804	206	7	in	in	ADP
fnp-3804	206	8	a	a	DET
fnp-3804	206	9	retrospective	retrospective	ADJ
fnp-3804	206	10	cohort	cohort	NOUN
fnp-3804	206	11	of	of	ADP
fnp-3804	206	12	514	514	NUM
fnp-3804	206	13	patients	patient	NOUN
fnp-3804	206	14	,	,	PUNCT
fnp-3804	206	15	and	and	CCONJ
fnp-3804	206	16	validated	validate	VERB
fnp-3804	206	17	on	on	ADP
fnp-3804	206	18	a	a	DET
fnp-3804	206	19	retrospective	retrospective	ADJ
fnp-3804	206	20	cohort	cohort	NOUN
fnp-3804	206	21	of	of	ADP
fnp-3804	206	22	184	184	NUM
fnp-3804	206	23	as	as	ADV
fnp-3804	206	24	well	well	ADV
fnp-3804	206	25	as	as	ADP
fnp-3804	206	26	on	on	ADP
fnp-3804	206	27	a	a	DET
fnp-3804	206	28	prospective	prospective	ADJ
fnp-3804	206	29	cohort	cohort	NOUN
fnp-3804	206	30	of	of	ADP
fnp-3804	206	31	287	287	NUM
fnp-3804	206	32	cases	case	NOUN
fnp-3804	206	33	.	.	PUNCT
fnp-3804	207	1	combining	combine	VERB
fnp-3804	207	2	different	different	ADJ
fnp-3804	207	3	risk	risk	NOUN
fnp-3804	207	4	stratification	stratification	NOUN
fnp-3804	207	5	approaches	approach	VERB
fnp-3804	207	6	into	into	ADP
fnp-3804	207	7	an	an	DET
fnp-3804	207	8	integrated	integrate	VERB
fnp-3804	207	9	molecular	molecular	ADJ
fnp-3804	207	10	-	-	PUNCT
fnp-3804	207	11	morphologic	morphologic	ADJ
fnp-3804	207	12	score	score	NOUN
fnp-3804	207	13	resulted	result	VERB
fnp-3804	207	14	in	in	ADP
fnp-3804	207	15	substantial	substantial	ADJ
fnp-3804	207	16	further	further	ADJ
fnp-3804	207	17	increase	increase	NOUN
fnp-3804	207	18	in	in	ADP
fnp-3804	207	19	accuracy	accuracy	NOUN
fnp-3804	207	20	.	.	PUNCT
fnp-3804	208	1	again	again	ADV
fnp-3804	208	2	(	(	PUNCT
fnp-3804	208	3	like	like	INTJ
fnp-3804	208	4	in	in	ADP
fnp-3804	208	5	the	the	DET
fnp-3804	208	6	study	study	NOUN
fnp-3804	208	7	of	of	ADP
fnp-3804	208	8	driver	driver	NOUN
fnp-3804	208	9	et	et	PROPN
fnp-3804	208	10	al	al	PROPN
fnp-3804	208	11	.	.	PROPN
fnp-3804	208	12	)	)	PUNCT
fnp-3804	208	13	,	,	PUNCT
fnp-3804	208	14	the	the	DET
fnp-3804	208	15	integrated	integrate	VERB
fnp-3804	208	16	scores	score	NOUN
fnp-3804	208	17	were	be	AUX
fnp-3804	208	18	found	find	VERB
fnp-3804	208	19	to	to	PART
fnp-3804	208	20	separate	separate	VERB
fnp-3804	208	21	tumors	tumor	NOUN
fnp-3804	208	22	more	more	ADV
fnp-3804	208	23	precisely	precisely	ADV
fnp-3804	208	24	for	for	ADP
fnp-3804	208	25	risk	risk	NOUN
fnp-3804	208	26	of	of	ADP
fnp-3804	208	27	progression	progression	NOUN
fnp-3804	208	28	,	,	PUNCT
fnp-3804	208	29	especially	especially	ADV
fnp-3804	208	30	so	so	ADV
fnp-3804	208	31	at	at	ADP
fnp-3804	208	32	the	the	DET
fnp-3804	208	33	diagnostically	diagnostically	ADV
fnp-3804	208	34	challenging	challenging	ADJ
fnp-3804	208	35	interface	interface	NOUN
fnp-3804	208	36	of	of	ADP
fnp-3804	208	37	cns	cns	PROPN
fnp-3804	208	38	who	who	PRON
fnp-3804	208	39	grade	grade	VERB
fnp-3804	208	40	1	1	NUM
fnp-3804	208	41	and	and	CCONJ
fnp-3804	208	42	grade	grade	NOUN
fnp-3804	208	43	2	2	NUM
fnp-3804	208	44	tumors	tumor	NOUN
fnp-3804	208	45	.	.	PUNCT
fnp-3804	209	1	discussion	discussion	NOUN
fnp-3804	209	2	in	in	ADP
fnp-3804	209	3	2021	2021	NUM
fnp-3804	209	4	again	again	ADV
fnp-3804	209	5	an	an	DET
fnp-3804	209	6	amazing	amazing	ADJ
fnp-3804	209	7	amount	amount	NOUN
fnp-3804	209	8	of	of	ADP
fnp-3804	209	9	information	information	NOUN
fnp-3804	209	10	with	with	ADP
fnp-3804	209	11	relevance	relevance	NOUN
fnp-3804	209	12	for	for	ADP
fnp-3804	209	13	neurooncological	neurooncological	ADJ
fnp-3804	209	14	pathology	pathology	NOUN
fnp-3804	209	15	has	have	AUX
fnp-3804	209	16	been	be	AUX
fnp-3804	209	17	published	publish	VERB
fnp-3804	209	18	.	.	PUNCT
fnp-3804	210	1	hopefully	hopefully	ADV
fnp-3804	210	2	,	,	PUNCT
fnp-3804	210	3	this	this	DET
fnp-3804	210	4	review	review	NOUN
fnp-3804	210	5	helps	help	VERB
fnp-3804	210	6	readers	reader	NOUN
fnp-3804	210	7	keep	keep	VERB
fnp-3804	210	8	up	up	ADP
fnp-3804	210	9	with	with	ADP
fnp-3804	210	10	what	what	PRON
fnp-3804	210	11	’s	’	VERB
fnp-3804	210	12	new	new	ADJ
fnp-3804	210	13	in	in	ADP
fnp-3804	210	14	this	this	DET
fnp-3804	210	15	respect	respect	NOUN
fnp-3804	210	16	.	.	PUNCT
fnp-3804	211	1	like	like	ADP
fnp-3804	211	2	who	who	PRON
fnp-3804	211	3	tumor	tumor	VERB
fnp-3804	211	4	classifications	classification	NOUN
fnp-3804	211	5	in	in	ADP
fnp-3804	211	6	general	general	ADJ
fnp-3804	211	7	,	,	PUNCT
fnp-3804	211	8	and	and	CCONJ
fnp-3804	211	9	as	as	SCONJ
fnp-3804	211	10	already	already	ADV
fnp-3804	211	11	stated	state	VERB
fnp-3804	211	12	in	in	ADP
fnp-3804	211	13	the	the	DET
fnp-3804	211	14	section	section	NOUN
fnp-3804	211	15	on	on	ADP
fnp-3804	211	16	topic	topic	NOUN
fnp-3804	211	17	1	1	NUM
fnp-3804	211	18	,	,	PUNCT
fnp-3804	211	19	the	the	PRON
fnp-3804	211	20	who	who	PRON
fnp-3804	211	21	cns5	cns5	PROPN
fnp-3804	211	22	classification	classification	NOUN
fnp-3804	211	23	represents	represent	VERB
fnp-3804	211	24	work	work	NOUN
fnp-3804	211	25	in	in	ADP
fnp-3804	211	26	progress	progress	NOUN
fnp-3804	211	27	with	with	ADP
fnp-3804	211	28	room	room	NOUN
fnp-3804	211	29	for	for	ADP
fnp-3804	211	30	further	further	ADJ
fnp-3804	211	31	improvements	improvement	NOUN
fnp-3804	211	32	.	.	PUNCT
fnp-3804	212	1	obviously	obviously	ADV
fnp-3804	212	2	,	,	PUNCT
fnp-3804	212	3	this	this	DET
fnp-3804	212	4	new	new	ADJ
fnp-3804	212	5	classification	classification	NOUN
fnp-3804	212	6	brings	bring	VERB
fnp-3804	212	7	further	further	ADJ
fnp-3804	212	8	challenges	challenge	NOUN
fnp-3804	212	9	as	as	ADV
fnp-3804	212	10	well	well	ADV
fnp-3804	212	11	.	.	PUNCT
fnp-3804	213	1	for	for	ADP
fnp-3804	213	2	example	example	NOUN
fnp-3804	213	3	,	,	PUNCT
fnp-3804	213	4	for	for	ADP
fnp-3804	213	5	more	more	ADJ
fnp-3804	213	6	cns	cns	NOUN
fnp-3804	213	7	tumors	tumor	NOUN
fnp-3804	213	8	it	it	PRON
fnp-3804	213	9	is	be	AUX
fnp-3804	213	10	now	now	ADV
fnp-3804	213	11	impossible	impossible	ADJ
fnp-3804	213	12	to	to	PART
fnp-3804	213	13	reach	reach	VERB
fnp-3804	213	14	a	a	DET
fnp-3804	213	15	state	state	NOUN
fnp-3804	213	16	-	-	PUNCT
fnp-3804	213	17	of	of	ADP
fnp-3804	213	18	-	-	PUNCT
fnp-3804	213	19	the	the	DET
fnp-3804	213	20	-	-	PUNCT
fnp-3804	213	21	art	art	NOUN
fnp-3804	213	22	‘	'	PUNCT
fnp-3804	213	23	histomolecular	histomolecular	ADJ
fnp-3804	213	24	’	'	PUNCT
fnp-3804	213	25	diagnosis	diagnosis	NOUN
fnp-3804	213	26	in	in	ADP
fnp-3804	213	27	case	case	NOUN
fnp-3804	213	28	molecular	molecular	ADJ
fnp-3804	213	29	tools	tool	NOUN
fnp-3804	213	30	for	for	ADP
fnp-3804	213	31	assessment	assessment	NOUN
fnp-3804	213	32	of	of	ADP
fnp-3804	213	33	essential	essential	ADJ
fnp-3804	213	34	diagnostic	diagnostic	ADJ
fnp-3804	213	35	characteristics	characteristic	NOUN
fnp-3804	213	36	(	(	PUNCT
fnp-3804	213	37	or	or	CCONJ
fnp-3804	213	38	immunohistochemistry	immunohistochemistry	VERB
fnp-3804	213	39	for	for	ADP
fnp-3804	213	40	reliable	reliable	ADJ
fnp-3804	213	41	surrogate	surrogate	ADJ
fnp-3804	213	42	markers	marker	NOUN
fnp-3804	213	43	,	,	PUNCT
fnp-3804	213	44	see	see	VERB
fnp-3804	213	45	below	below	ADV
fnp-3804	213	46	)	)	PUNCT
fnp-3804	213	47	are	be	AUX
fnp-3804	213	48	not	not	PART
fnp-3804	213	49	available	available	ADJ
fnp-3804	213	50	.	.	PUNCT
fnp-3804	214	1	in	in	ADP
fnp-3804	214	2	those	those	DET
fnp-3804	214	3	situations	situation	NOUN
fnp-3804	214	4	,	,	PUNCT
fnp-3804	214	5	adding	add	VERB
fnp-3804	214	6	nos	nos	PROPN
fnp-3804	214	7	(	(	PUNCT
fnp-3804	214	8	not	not	PART
fnp-3804	214	9	otherwise	otherwise	ADV
fnp-3804	214	10	specified	specify	VERB
fnp-3804	214	11	)	)	PUNCT
fnp-3804	214	12	to	to	ADP
fnp-3804	214	13	the	the	DET
fnp-3804	214	14	histology	histology	NOUN
fnp-3804	214	15	-	-	PUNCT
fnp-3804	214	16	based	base	VERB
fnp-3804	214	17	diagnosis	diagnosis	NOUN
fnp-3804	214	18	is	be	AUX
fnp-3804	214	19	the	the	DET
fnp-3804	214	20	way	way	NOUN
fnp-3804	214	21	to	to	PART
fnp-3804	214	22	go	go	VERB
fnp-3804	214	23	35	35	NUM
fnp-3804	214	24	.	.	PUNCT
fnp-3804	215	1	furthermore	furthermore	ADV
fnp-3804	215	2	,	,	PUNCT
fnp-3804	215	3	designing	design	VERB
fnp-3804	215	4	the	the	DET
fnp-3804	215	5	optimal	optimal	ADJ
fnp-3804	215	6	therapeutic	therapeutic	ADJ
fnp-3804	215	7	management	management	NOUN
fnp-3804	215	8	for	for	ADP
fnp-3804	215	9	newly	newly	ADV
fnp-3804	215	10	defined	define	VERB
fnp-3804	215	11	tumor	tumor	NOUN
fnp-3804	215	12	types	type	NOUN
fnp-3804	215	13	is	be	AUX
fnp-3804	215	14	challenging	challenging	ADJ
fnp-3804	215	15	.	.	PUNCT
fnp-3804	216	1	and	and	CCONJ
fnp-3804	216	2	while	while	SCONJ
fnp-3804	216	3	a	a	DET
fnp-3804	216	4	more	more	ADV
fnp-3804	216	5	precise	precise	ADJ
fnp-3804	216	6	classification	classification	NOUN
fnp-3804	216	7	facilitates	facilitate	VERB
fnp-3804	216	8	enrollment	enrollment	NOUN
fnp-3804	216	9	of	of	ADP
fnp-3804	216	10	more	more	ADV
fnp-3804	216	11	homogeneous	homogeneous	ADJ
fnp-3804	216	12	populations	population	NOUN
fnp-3804	216	13	of	of	ADP
fnp-3804	216	14	patients	patient	NOUN
fnp-3804	216	15	in	in	ADP
fnp-3804	216	16	clinical	clinical	ADJ
fnp-3804	216	17	studies	study	NOUN
fnp-3804	216	18	,	,	PUNCT
fnp-3804	216	19	the	the	DET
fnp-3804	216	20	higher	high	ADJ
fnp-3804	216	21	granularity	granularity	NOUN
fnp-3804	216	22	of	of	ADP
fnp-3804	216	23	cns	cns	PROPN
fnp-3804	216	24	tumor	tumor	NOUN
fnp-3804	216	25	taxonomy	taxonomy	NOUN
fnp-3804	216	26	makes	make	VERB
fnp-3804	216	27	it	it	PRON
fnp-3804	216	28	more	more	ADV
fnp-3804	216	29	difficult	difficult	ADJ
fnp-3804	216	30	to	to	PART
fnp-3804	216	31	perform	perform	VERB
fnp-3804	216	32	studies	study	NOUN
fnp-3804	216	33	on	on	ADP
fnp-3804	216	34	a	a	DET
fnp-3804	216	35	large	large	ADJ
fnp-3804	216	36	number	number	NOUN
fnp-3804	216	37	of	of	ADP
fnp-3804	216	38	patients	patient	NOUN
fnp-3804	216	39	for	for	ADP
fnp-3804	216	40	particular	particular	ADJ
fnp-3804	216	41	tumor	tumor	NOUN
fnp-3804	216	42	types	type	NOUN
fnp-3804	216	43	.	.	PUNCT
fnp-3804	217	1	still	still	ADV
fnp-3804	217	2	,	,	PUNCT
fnp-3804	217	3	one	one	PRON
fnp-3804	217	4	would	would	AUX
fnp-3804	217	5	like	like	VERB
fnp-3804	217	6	to	to	PART
fnp-3804	217	7	think	think	VERB
fnp-3804	217	8	that	that	SCONJ
fnp-3804	217	9	patients	patient	NOUN
fnp-3804	217	10	suffering	suffer	VERB
fnp-3804	217	11	from	from	ADP
fnp-3804	217	12	a	a	DET
fnp-3804	217	13	cns	cns	NOUN
fnp-3804	217	14	tumor	tumor	NOUN
fnp-3804	217	15	are	be	AUX
fnp-3804	217	16	better	well	ADV
fnp-3804	217	17	served	serve	VERB
fnp-3804	217	18	by	by	ADP
fnp-3804	217	19	a	a	DET
fnp-3804	217	20	more	more	ADV
fnp-3804	217	21	precise	precise	ADJ
fnp-3804	217	22	diagnosis	diagnosis	NOUN
fnp-3804	217	23	because	because	SCONJ
fnp-3804	217	24	this	this	PRON
fnp-3804	217	25	allows	allow	VERB
fnp-3804	217	26	for	for	ADP
fnp-3804	217	27	a	a	DET
fnp-3804	217	28	better	well	ADJ
fnp-3804	217	29	estimation	estimation	NOUN
fnp-3804	217	30	of	of	ADP
fnp-3804	217	31	prognosis	prognosis	NOUN
fnp-3804	217	32	and	and	CCONJ
fnp-3804	217	33	,	,	PUNCT
fnp-3804	217	34	hopefully	hopefully	ADV
fnp-3804	217	35	sooner	soon	ADV
fnp-3804	217	36	than	than	ADP
fnp-3804	217	37	later	later	ADV
fnp-3804	217	38	,	,	PUNCT
fnp-3804	217	39	for	for	ADP
fnp-3804	217	40	a	a	DET
fnp-3804	217	41	more	more	ADV
fnp-3804	217	42	tailored	tailored	ADJ
fnp-3804	217	43	and	and	CCONJ
fnp-3804	217	44	effective	effective	ADJ
fnp-3804	217	45	therapeutic	therapeutic	ADJ
fnp-3804	217	46	approach	approach	NOUN
fnp-3804	217	47	.	.	PUNCT
fnp-3804	218	1	immunohistochemistry	immunohistochemistry	NOUN
fnp-3804	218	2	for	for	ADP
fnp-3804	218	3	surrogate	surrogate	ADJ
fnp-3804	218	4	markers	marker	NOUN
fnp-3804	218	5	can	can	AUX
fnp-3804	218	6	indeed	indeed	ADV
fnp-3804	218	7	provide	provide	VERB
fnp-3804	218	8	a	a	DET
fnp-3804	218	9	way	way	NOUN
fnp-3804	218	10	for	for	ADP
fnp-3804	218	11	making	make	VERB
fnp-3804	218	12	a	a	DET
fnp-3804	218	13	bona	bona	ADJ
fnp-3804	218	14	fide	fide	NOUN
fnp-3804	218	15	,	,	PUNCT
fnp-3804	218	16	‘	'	PUNCT
fnp-3804	218	17	histomolecular	histomolecular	ADJ
fnp-3804	218	18	’	'	PUNCT
fnp-3804	218	19	who	who	PRON
fnp-3804	218	20	cns5	cns5	VERB
fnp-3804	218	21	diagnosis	diagnosis	VERB
fnp-3804	218	22	.	.	PUNCT
fnp-3804	219	1	some	some	DET
fnp-3804	219	2	examples	example	NOUN
fnp-3804	219	3	of	of	ADP
fnp-3804	219	4	stains	stain	NOUN
fnp-3804	219	5	that	that	PRON
fnp-3804	219	6	are	be	AUX
fnp-3804	219	7	already	already	ADV
fnp-3804	219	8	often	often	ADV
fnp-3804	219	9	used	use	VERB
fnp-3804	219	10	in	in	ADP
fnp-3804	219	11	clinical	clinical	ADJ
fnp-3804	219	12	practice	practice	NOUN
fnp-3804	219	13	are	be	AUX
fnp-3804	219	14	immunohistochemistry	immunohistochemistry	NOUN
fnp-3804	219	15	for	for	ADP
fnp-3804	219	16	mutant	mutant	ADJ
fnp-3804	219	17	proteins	protein	NOUN
fnp-3804	219	18	(	(	PUNCT
fnp-3804	219	19	idh1	idh1	PROPN
fnp-3804	219	20	r132h	r132h	PROPN
fnp-3804	219	21	,	,	PUNCT
fnp-3804	219	22	h3	h3	VERB
fnp-3804	219	23	k27	k27	PROPN
fnp-3804	219	24	m	m	PROPN
fnp-3804	219	25	,	,	PUNCT
fnp-3804	219	26	h3	h3	NOUN
fnp-3804	219	27	g34v	g34v	PROPN
fnp-3804	219	28	/	/	SYM
fnp-3804	219	29	r	r	NOUN
fnp-3804	219	30	,	,	PUNCT
fnp-3804	219	31	braf	braf	NOUN
fnp-3804	219	32	v600e	v600e	PROPN
fnp-3804	219	33	)	)	PUNCT
fnp-3804	219	34	,	,	PUNCT
fnp-3804	219	35	for	for	ADP
fnp-3804	219	36	loss	loss	NOUN
fnp-3804	219	37	of	of	ADP
fnp-3804	219	38	staining	stain	VERB
fnp-3804	219	39	for	for	ADP
fnp-3804	219	40	normal	normal	ADJ
fnp-3804	219	41	proteins	protein	NOUN
fnp-3804	219	42	in	in	ADP
fnp-3804	219	43	the	the	DET
fnp-3804	219	44	tumor	tumor	NOUN
fnp-3804	219	45	cell	cell	NOUN
fnp-3804	219	46	nuclei	nucleus	NOUN
fnp-3804	219	47	(	(	PUNCT
fnp-3804	219	48	atrx	atrx	PROPN
fnp-3804	219	49	,	,	PUNCT
fnp-3804	219	50	ini1	ini1	PROPN
fnp-3804	219	51	,	,	PUNCT
fnp-3804	219	52	brg1	brg1	PROPN
fnp-3804	219	53	,	,	PUNCT
fnp-3804	219	54	h3k27me3	h3k27me3	PROPN
fnp-3804	219	55	)	)	PUNCT
fnp-3804	219	56	,	,	PUNCT
fnp-3804	219	57	and	and	CCONJ
fnp-3804	219	58	for	for	ADP
fnp-3804	219	59	abnormal	abnormal	ADJ
fnp-3804	219	60	location	location	NOUN
fnp-3804	219	61	or	or	CCONJ
fnp-3804	219	62	intensity	intensity	NOUN
fnp-3804	219	63	of	of	ADP
fnp-3804	219	64	a	a	DET
fnp-3804	219	65	protein	protein	NOUN
fnp-3804	219	66	in	in	ADP
fnp-3804	219	67	the	the	DET
fnp-3804	219	68	tumor	tumor	NOUN
fnp-3804	219	69	cell	cell	NOUN
fnp-3804	219	70	nuclei	nucleus	NOUN
fnp-3804	219	71	(	(	PUNCT
fnp-3804	219	72	e.g.	e.g.	ADV
fnp-3804	219	73	stat6	stat6	NOUN
fnp-3804	219	74	,	,	PUNCT
fnp-3804	219	75	p53	p53	NOUN
fnp-3804	219	76	)	)	PUNCT
fnp-3804	219	77	.	.	PUNCT
fnp-3804	220	1	the	the	DET
fnp-3804	220	2	information	information	NOUN
fnp-3804	220	3	provided	provide	VERB
fnp-3804	220	4	by	by	ADP
fnp-3804	220	5	the	the	DET
fnp-3804	220	6	studies	study	NOUN
fnp-3804	220	7	of	of	ADP
fnp-3804	220	8	driver	driver	NOUN
fnp-3804	220	9	et	et	PROPN
fnp-3804	220	10	al	al	PROPN
fnp-3804	220	11	.	.	PROPN
fnp-3804	220	12	and	and	CCONJ
fnp-3804	220	13	of	of	ADP
fnp-3804	220	14	maas	maas	PROPN
fnp-3804	220	15	et	et	PROPN
fnp-3804	220	16	al	al	PROPN
fnp-3804	220	17	.	.	PUNCT
fnp-3804	221	1	(	(	PUNCT
fnp-3804	221	2	see	see	VERB
fnp-3804	221	3	topic	topic	NOUN
fnp-3804	221	4	10	10	NUM
fnp-3804	221	5	)	)	PUNCT
fnp-3804	221	6	shows	show	VERB
fnp-3804	221	7	that	that	SCONJ
fnp-3804	221	8	the	the	DET
fnp-3804	221	9	care	care	NOUN
fnp-3804	221	10	for	for	ADP
fnp-3804	221	11	patients	patient	NOUN
fnp-3804	221	12	with	with	ADP
fnp-3804	221	13	meningioma	meningioma	NOUN
fnp-3804	221	14	can	can	AUX
fnp-3804	221	15	be	be	AUX
fnp-3804	221	16	improved	improve	VERB
fnp-3804	221	17	by	by	ADP
fnp-3804	221	18	assessment	assessment	NOUN
fnp-3804	221	19	of	of	ADP
fnp-3804	221	20	particular	particular	ADJ
fnp-3804	221	21	molecular	molecular	ADJ
fnp-3804	221	22	characteristics	characteristic	NOUN
fnp-3804	221	23	for	for	ADP
fnp-3804	221	24	the	the	DET
fnp-3804	221	25	grading	grading	NOUN
fnp-3804	221	26	of	of	ADP
fnp-3804	221	27	these	these	DET
fnp-3804	221	28	tumors	tumor	NOUN
fnp-3804	221	29	13,14	13,14	ADV
fnp-3804	221	30	.	.	PUNCT
fnp-3804	222	1	at	at	ADP
fnp-3804	222	2	the	the	DET
fnp-3804	222	3	same	same	ADJ
fnp-3804	222	4	time	time	NOUN
fnp-3804	222	5	,	,	PUNCT
fnp-3804	222	6	there	there	PRON
fnp-3804	222	7	may	may	AUX
fnp-3804	222	8	be	be	AUX
fnp-3804	222	9	an	an	DET
fnp-3804	222	10	opportunity	opportunity	NOUN
fnp-3804	222	11	for	for	ADP
fnp-3804	222	12	immunohistochemistry	immunohistochemistry	NOUN
fnp-3804	222	13	here	here	ADV
fnp-3804	222	14	as	as	ADV
fnp-3804	222	15	well	well	ADV
fnp-3804	222	16	:	:	PUNCT
fnp-3804	222	17	for	for	ADP
fnp-3804	222	18	example	example	NOUN
fnp-3804	222	19	,	,	PUNCT
fnp-3804	222	20	loss	loss	NOUN
fnp-3804	222	21	of	of	ADP
fnp-3804	222	22	h3k27me3	h3k27me3	PROPN
fnp-3804	222	23	staining	stain	VERB
fnp-3804	222	24	of	of	ADP
fnp-3804	222	25	tumor	tumor	NOUN
fnp-3804	222	26	cell	cell	NOUN
fnp-3804	222	27	nuclei	nucleus	NOUN
fnp-3804	222	28	in	in	ADP
fnp-3804	222	29	meningioma	meningioma	NOUN
fnp-3804	222	30	has	have	AUX
fnp-3804	222	31	been	be	AUX
fnp-3804	222	32	reported	report	VERB
fnp-3804	222	33	as	as	ADP
fnp-3804	222	34	an	an	DET
fnp-3804	222	35	additional	additional	ADJ
fnp-3804	222	36	tool	tool	NOUN
fnp-3804	222	37	for	for	ADP
fnp-3804	222	38	identification	identification	NOUN
fnp-3804	222	39	of	of	ADP
fnp-3804	222	40	meningiomas	meningioma	NOUN
fnp-3804	222	41	with	with	ADP
fnp-3804	222	42	higher	high	ADJ
fnp-3804	222	43	risk	risk	NOUN
fnp-3804	222	44	of	of	ADP
fnp-3804	222	45	recurrence	recurrence	NOUN
fnp-3804	222	46	36,37	36,37	NUM
fnp-3804	222	47	.	.	PUNCT
fnp-3804	223	1	furthermore	furthermore	ADV
fnp-3804	223	2	,	,	PUNCT
fnp-3804	223	3	in	in	ADP
fnp-3804	223	4	the	the	DET
fnp-3804	223	5	study	study	NOUN
fnp-3804	223	6	of	of	ADP
fnp-3804	223	7	nassiri	nassiri	NOUN
fnp-3804	223	8	f	f	PROPN
fnp-3804	223	9	et	et	PROPN
fnp-3804	223	10	al	al	PROPN
fnp-3804	223	11	.	.	PUNCT
fnp-3804	224	1	(	(	PUNCT
fnp-3804	224	2	see	see	VERB
fnp-3804	224	3	topic	topic	NOUN
fnp-3804	224	4	10	10	NUM
fnp-3804	224	5	)	)	PUNCT
fnp-3804	224	6	,	,	PUNCT
fnp-3804	224	7	particular	particular	ADJ
fnp-3804	224	8	proteins	protein	NOUN
fnp-3804	224	9	were	be	AUX
fnp-3804	224	10	found	find	VERB
fnp-3804	224	11	to	to	PART
fnp-3804	224	12	be	be	AUX
fnp-3804	224	13	highly	highly	ADV
fnp-3804	224	14	enriched	enrich	VERB
fnp-3804	224	15	in	in	ADP
fnp-3804	224	16	the	the	DET
fnp-3804	224	17	different	different	ADJ
fnp-3804	224	18	molecular	molecular	ADJ
fnp-3804	224	19	groups	group	NOUN
fnp-3804	224	20	(	(	PUNCT
fnp-3804	224	21	mg1	mg1	NOUN
fnp-3804	224	22	:	:	PUNCT
fnp-3804	224	23	s100b	s100b	PROPN
fnp-3804	224	24	;	;	PUNCT
fnp-3804	224	25	mg2	mg2	PROPN
fnp-3804	224	26	:	:	PUNCT
fnp-3804	224	27	scgn	scgn	PROPN
fnp-3804	224	28	;	;	PUNCT
fnp-3804	224	29	mg3	mg3	PROPN
fnp-3804	224	30	:	:	PUNCT
fnp-3804	224	31	acadl	acadl	NOUN
fnp-3804	224	32	;	;	PUNCT
fnp-3804	224	33	mg4	mg4	PROPN
fnp-3804	224	34	:	:	PUNCT
fnp-3804	224	35	mcm2	mcm2	ADJ
fnp-3804	224	36	)	)	PUNCT
fnp-3804	224	37	12	12	NUM
fnp-3804	224	38	.	.	PUNCT
fnp-3804	225	1	further	further	ADJ
fnp-3804	225	2	validation	validation	NOUN
fnp-3804	225	3	of	of	ADP
fnp-3804	225	4	such	such	ADJ
fnp-3804	225	5	immunohistochemical	immunohistochemical	ADJ
fnp-3804	225	6	approaches	approach	NOUN
fnp-3804	225	7	and	and	CCONJ
fnp-3804	225	8	comparison	comparison	NOUN
fnp-3804	225	9	with	with	ADP
fnp-3804	225	10	the	the	DET
fnp-3804	225	11	results	result	NOUN
fnp-3804	225	12	as	as	SCONJ
fnp-3804	225	13	presented	present	VERB
fnp-3804	225	14	by	by	ADP
fnp-3804	225	15	driver	driver	NOUN
fnp-3804	225	16	et	et	PROPN
fnp-3804	225	17	al	al	PROPN
fnp-3804	225	18	.	.	PROPN
fnp-3804	225	19	and	and	CCONJ
fnp-3804	225	20	by	by	ADP
fnp-3804	225	21	maas	maas	PROPN
fnp-3804	225	22	et	et	PROPN
fnp-3804	225	23	al	al	PROPN
fnp-3804	225	24	.	.	PROPN
fnp-3804	225	25	is	be	AUX
fnp-3804	225	26	needed	need	VERB
fnp-3804	225	27	.	.	PUNCT
fnp-3804	226	1	also	also	ADV
fnp-3804	226	2	,	,	PUNCT
fnp-3804	226	3	acknowledging	acknowledge	VERB
fnp-3804	226	4	that	that	SCONJ
fnp-3804	226	5	the	the	DET
fnp-3804	226	6	molecular	molecular	ADJ
fnp-3804	226	7	underpinnings	underpinning	NOUN
fnp-3804	226	8	in	in	ADP
fnp-3804	226	9	meningiomas	meningioma	NOUN
fnp-3804	226	10	diagnosed	diagnose	VERB
fnp-3804	226	11	in	in	ADP
fnp-3804	226	12	kids	kid	NOUN
fnp-3804	226	13	are	be	AUX
fnp-3804	226	14	distinct	distinct	ADJ
fnp-3804	226	15	from	from	ADP
fnp-3804	226	16	those	those	PRON
fnp-3804	226	17	in	in	ADP
fnp-3804	226	18	adults	adult	NOUN
fnp-3804	226	19	38	38	NUM
fnp-3804	226	20	,	,	PUNCT
fnp-3804	226	21	pediatric	pediatric	ADJ
fnp-3804	226	22	meningiomas	meningioma	NOUN
fnp-3804	226	23	may	may	AUX
fnp-3804	226	24	require	require	VERB
fnp-3804	226	25	an	an	DET
fnp-3804	226	26	adapted	adapt	VERB
fnp-3804	226	27	grading	grade	VERB
fnp-3804	226	28	system	system	NOUN
fnp-3804	226	29	.	.	PUNCT
fnp-3804	227	1	while	while	SCONJ
fnp-3804	227	2	cns	cns	PROPN
fnp-3804	227	3	tumors	tumor	NOUN
fnp-3804	227	4	can	can	AUX
fnp-3804	227	5	now	now	ADV
fnp-3804	227	6	be	be	AUX
fnp-3804	227	7	much	much	ADV
fnp-3804	227	8	more	more	ADV
fnp-3804	227	9	precisely	precisely	ADV
fnp-3804	227	10	characterized	characterized	ADJ
fnp-3804	227	11	than	than	ADP
fnp-3804	227	12	a	a	DET
fnp-3804	227	13	few	few	ADJ
fnp-3804	227	14	decades	decade	NOUN
fnp-3804	227	15	ago	ago	ADV
fnp-3804	227	16	,	,	PUNCT
fnp-3804	227	17	the	the	DET
fnp-3804	227	18	translation	translation	NOUN
fnp-3804	227	19	of	of	ADP
fnp-3804	227	20	this	this	DET
fnp-3804	227	21	increased	increase	VERB
fnp-3804	227	22	knowledge	knowledge	NOUN
fnp-3804	227	23	into	into	ADP
fnp-3804	227	24	more	more	ADV
fnp-3804	227	25	effective	effective	ADJ
fnp-3804	227	26	treatments	treatment	NOUN
fnp-3804	227	27	is	be	AUX
fnp-3804	227	28	seriously	seriously	ADV
fnp-3804	227	29	lagging	lag	VERB
fnp-3804	227	30	behind	behind	ADV
fnp-3804	227	31	.	.	PUNCT
fnp-3804	228	1	quite	quite	DET
fnp-3804	228	2	some	some	PRON
fnp-3804	228	3	of	of	ADP
fnp-3804	228	4	the	the	DET
fnp-3804	228	5	topics	topic	NOUN
fnp-3804	228	6	discussed	discuss	VERB
fnp-3804	228	7	in	in	ADP
fnp-3804	228	8	this	this	DET
fnp-3804	228	9	review	review	NOUN
fnp-3804	228	10	concern	concern	NOUN
fnp-3804	228	11	studies	study	NOUN
fnp-3804	228	12	that	that	PRON
fnp-3804	228	13	further	far	ADV
fnp-3804	228	14	elucidate	elucidate	VERB
fnp-3804	228	15	the	the	DET
fnp-3804	228	16	pathobiology	pathobiology	NOUN
fnp-3804	228	17	of	of	ADP
fnp-3804	228	18	particular	particular	ADJ
fnp-3804	228	19	cns	cns	NOUN
fnp-3804	228	20	tumors	tumor	NOUN
fnp-3804	228	21	.	.	PUNCT
fnp-3804	229	1	hopefully	hopefully	ADV
fnp-3804	229	2	,	,	PUNCT
fnp-3804	229	3	such	such	ADJ
fnp-3804	229	4	knowledge	knowledge	NOUN
fnp-3804	229	5	can	can	AUX
fnp-3804	229	6	be	be	AUX
fnp-3804	229	7	exploited	exploit	VERB
fnp-3804	229	8	for	for	ADP
fnp-3804	229	9	more	more	ADV
fnp-3804	229	10	effective	effective	ADJ
fnp-3804	229	11	therapies	therapy	NOUN
fnp-3804	229	12	as	as	ADV
fnp-3804	229	13	well	well	ADV
fnp-3804	229	14	,	,	PUNCT
fnp-3804	229	15	e.g.	e.g.	ADV
fnp-3804	229	16	,	,	PUNCT
fnp-3804	229	17	by	by	ADP
fnp-3804	229	18	targeting	target	VERB
fnp-3804	229	19	of	of	ADP
fnp-3804	229	20	epigenetic	epigenetic	ADJ
fnp-3804	229	21	regulation	regulation	NOUN
fnp-3804	229	22	of	of	ADP
fnp-3804	229	23	neural	neural	ADJ
fnp-3804	229	24	or	or	CCONJ
fnp-3804	229	25	oligodendrocyte	oligodendrocyte	ADJ
fnp-3804	229	26	precursor	precursor	NOUN
fnp-3804	229	27	states	state	NOUN
fnp-3804	229	28	/	/	SYM
fnp-3804	229	29	cells	cell	NOUN
fnp-3804	229	30	(	(	PUNCT
fnp-3804	229	31	topic	topic	NOUN
fnp-3804	229	32	4	4	NUM
fnp-3804	229	33	)	)	PUNCT
fnp-3804	229	34	,	,	PUNCT
fnp-3804	229	35	by	by	ADP
fnp-3804	229	36	remodeling	remodel	VERB
fnp-3804	229	37	the	the	DET
fnp-3804	229	38	epigenome	epigenome	NOUN
fnp-3804	229	39	of	of	ADP
fnp-3804	229	40	glioma	glioma	NOUN
fnp-3804	229	41	cells	cell	NOUN
fnp-3804	229	42	in	in	ADP
fnp-3804	229	43	order	order	NOUN
fnp-3804	229	44	to	to	PART
fnp-3804	229	45	alter	alter	VERB
fnp-3804	229	46	the	the	DET
fnp-3804	229	47	differentiation	differentiation	NOUN
fnp-3804	229	48	hierarchy	hierarchy	NOUN
fnp-3804	229	49	of	of	ADP
fnp-3804	229	50	gliomas	glioma	NOUN
fnp-3804	229	51	(	(	PUNCT
fnp-3804	229	52	topic	topic	NOUN
fnp-3804	229	53	5	5	NUM
fnp-3804	229	54	)	)	PUNCT
fnp-3804	229	55	,	,	PUNCT
fnp-3804	229	56	by	by	ADP
fnp-3804	229	57	exploiting	exploit	VERB
fnp-3804	229	58	the	the	DET
fnp-3804	229	59	new	new	ADJ
fnp-3804	229	60	information	information	NOUN
fnp-3804	229	61	obtained	obtain	VERB
fnp-3804	229	62	by	by	ADP
fnp-3804	229	63	multi	multi	ADJ
fnp-3804	229	64	-	-	ADJ
fnp-3804	229	65	omic	omic	ADJ
fnp-3804	229	66	investigations	investigation	NOUN
fnp-3804	229	67	for	for	ADP
fnp-3804	229	68	improved	improved	ADJ
fnp-3804	229	69	targeting	targeting	NOUN
fnp-3804	229	70	of	of	ADP
fnp-3804	229	71	the	the	DET
fnp-3804	229	72	pathways	pathway	NOUN
fnp-3804	229	73	involved	involve	VERB
fnp-3804	229	74	in	in	ADP
fnp-3804	229	75	glioblastomas	glioblastoma	NOUN
fnp-3804	229	76	(	(	PUNCT
fnp-3804	229	77	topic	topic	NOUN
fnp-3804	229	78	6	6	NUM
fnp-3804	229	79	)	)	PUNCT
fnp-3804	229	80	,	,	PUNCT
fnp-3804	229	81	and/or	and/or	CCONJ
fnp-3804	229	82	by	by	ADP
fnp-3804	229	83	improving	improve	VERB
fnp-3804	229	84	strategies	strategy	NOUN
fnp-3804	229	85	for	for	ADP
fnp-3804	229	86	selection	selection	NOUN
fnp-3804	229	87	of	of	ADP
fnp-3804	229	88	patients	patient	NOUN
fnp-3804	229	89	for	for	ADP
fnp-3804	229	90	targeted	target	VERB
fnp-3804	229	91	(	(	PUNCT
fnp-3804	229	92	immune)therapies	immune)therapie	NOUN
fnp-3804	229	93	based	base	VERB
fnp-3804	229	94	on	on	ADP
fnp-3804	229	95	immunophenotyping	immunophenotype	VERB
fnp-3804	229	96	studies	study	NOUN
fnp-3804	229	97	and	and	CCONJ
fnp-3804	229	98	information	information	NOUN
fnp-3804	229	99	on	on	ADP
fnp-3804	229	100	the	the	DET
fnp-3804	229	101	spatial	spatial	ADJ
fnp-3804	229	102	distribution	distribution	NOUN
fnp-3804	229	103	of	of	ADP
fnp-3804	229	104	genomic	genomic	ADJ
fnp-3804	229	105	alterations	alteration	NOUN
fnp-3804	229	106	of	of	ADP
fnp-3804	229	107	gliomas	glioma	NOUN
fnp-3804	229	108	/	/	SYM
fnp-3804	229	109	glioblastomas	glioblastoma	NOUN
fnp-3804	229	110	(	(	PUNCT
fnp-3804	229	111	topic	topic	NOUN
fnp-3804	229	112	7	7	NUM
fnp-3804	229	113	)	)	PUNCT
fnp-3804	229	114	.	.	PUNCT
fnp-3804	230	1	in	in	ADP
fnp-3804	230	2	a	a	DET
fnp-3804	230	3	study	study	NOUN
fnp-3804	230	4	of	of	ADP
fnp-3804	230	5	>	>	SYM
fnp-3804	230	6	10,000	10,000	NUM
fnp-3804	230	7	cancer	cancer	NOUN
fnp-3804	230	8	patients	patient	NOUN
fnp-3804	230	9	across	across	ADP
fnp-3804	230	10	20	20	NUM
fnp-3804	230	11	different	different	ADJ
fnp-3804	230	12	cancer	cancer	NOUN
fnp-3804	230	13	types	type	NOUN
fnp-3804	230	14	,	,	PUNCT
fnp-3804	230	15	transcriptomic	transcriptomic	ADJ
fnp-3804	230	16	analysis	analysis	NOUN
fnp-3804	230	17	allowed	allow	VERB
fnp-3804	230	18	for	for	ADP
fnp-3804	230	19	the	the	DET
fnp-3804	230	20	identification	identification	NOUN
fnp-3804	230	21	of	of	ADP
fnp-3804	230	22	four	four	NUM
fnp-3804	230	23	distinct	distinct	ADJ
fnp-3804	230	24	tumor	tumor	NOUN
fnp-3804	230	25	-	-	PUNCT
fnp-3804	230	26	microenvironment	microenvironment	NOUN
fnp-3804	230	27	subtypes	subtype	NOUN
fnp-3804	230	28	which	which	PRON
fnp-3804	230	29	correlated	correlate	VERB
fnp-3804	230	30	with	with	ADP
fnp-3804	230	31	patient	patient	ADJ
fnp-3804	230	32	response	response	NOUN
fnp-3804	230	33	to	to	ADP
fnp-3804	230	34	immunotherapy	immunotherapy	NOUN
fnp-3804	230	35	.	.	PUNCT
fnp-3804	231	1	by	by	ADP
fnp-3804	231	2	integrating	integrate	VERB
fnp-3804	231	3	transcriptomic	transcriptomic	ADJ
fnp-3804	231	4	and	and	CCONJ
fnp-3804	231	5	genomic	genomic	ADJ
fnp-3804	231	6	data	datum	NOUN
fnp-3804	231	7	,	,	PUNCT
fnp-3804	231	8	a	a	DET
fnp-3804	231	9	global	global	ADJ
fnp-3804	231	10	tumor	tumor	NOUN
fnp-3804	231	11	portrait	portrait	NOUN
fnp-3804	231	12	can	can	AUX
fnp-3804	231	13	be	be	AUX
fnp-3804	231	14	designed	design	VERB
fnp-3804	231	15	,	,	PUNCT
fnp-3804	231	16	describing	describe	VERB
fnp-3804	231	17	the	the	DET
fnp-3804	231	18	tumor	tumor	NOUN
fnp-3804	231	19	framework	framework	NOUN
fnp-3804	231	20	,	,	PUNCT
fnp-3804	231	21	mutational	mutational	ADJ
fnp-3804	231	22	load	load	NOUN
fnp-3804	231	23	,	,	PUNCT
fnp-3804	231	24	immune	immune	ADJ
fnp-3804	231	25	composition	composition	NOUN
fnp-3804	231	26	,	,	PUNCT
fnp-3804	231	27	anti	anti	ADJ
fnp-3804	231	28	-	-	ADJ
fnp-3804	231	29	tumor	tumor	ADJ
fnp-3804	231	30	immunity	immunity	NOUN
fnp-3804	231	31	,	,	PUNCT
fnp-3804	231	32	and	and	CCONJ
fnp-3804	231	33	immunosuppressive	immunosuppressive	ADJ
fnp-3804	231	34	escape	escape	NOUN
fnp-3804	231	35	mechanisms	mechanism	NOUN
fnp-3804	231	36	,	,	PUNCT
fnp-3804	231	37	guiding	guide	VERB
fnp-3804	231	38	therapeutic	therapeutic	ADJ
fnp-3804	231	39	decision	decision	NOUN
fnp-3804	231	40	-	-	PUNCT
fnp-3804	231	41	making	make	VERB
fnp-3804	231	42	39	39	NUM
fnp-3804	231	43	.	.	PUNCT
fnp-3804	232	1	the	the	DET
fnp-3804	232	2	finding	finding	NOUN
fnp-3804	232	3	that	that	SCONJ
fnp-3804	232	4	visual	visual	ADJ
fnp-3804	232	5	experience	experience	NOUN
fnp-3804	232	6	and	and	CCONJ
fnp-3804	232	7	neuronal	neuronal	ADJ
fnp-3804	232	8	activity	activity	NOUN
fnp-3804	232	9	is	be	AUX
fnp-3804	232	10	required	require	VERB
fnp-3804	232	11	for	for	ADP
fnp-3804	232	12	the	the	DET
fnp-3804	232	13	formation	formation	NOUN
fnp-3804	232	14	and	and	CCONJ
fnp-3804	232	15	growth	growth	NOUN
fnp-3804	232	16	of	of	ADP
fnp-3804	232	17	optic	optic	ADJ
fnp-3804	232	18	gliomas	glioma	NOUN
fnp-3804	232	19	may	may	AUX
fnp-3804	232	20	provide	provide	VERB
fnp-3804	232	21	new	new	ADJ
fnp-3804	232	22	targets	target	NOUN
fnp-3804	232	23	for	for	ADP
fnp-3804	232	24	therapeutic	therapeutic	ADJ
fnp-3804	232	25	interference	interference	NOUN
fnp-3804	232	26	for	for	ADP
fnp-3804	232	27	these	these	DET
fnp-3804	232	28	tumors	tumor	NOUN
fnp-3804	232	29	(	(	PUNCT
fnp-3804	232	30	topic	topic	NOUN
fnp-3804	232	31	3	3	NUM
fnp-3804	232	32	)	)	PUNCT
fnp-3804	232	33	,	,	PUNCT
fnp-3804	232	34	and	and	CCONJ
fnp-3804	232	35	maybe	maybe	ADV
fnp-3804	232	36	some	some	DET
fnp-3804	232	37	‘	'	PUNCT
fnp-3804	232	38	old	old	ADJ
fnp-3804	232	39	drugs	drug	NOUN
fnp-3804	232	40	’	'	PUNCT
fnp-3804	232	41	can	can	AUX
fnp-3804	232	42	indeed	indeed	ADV
fnp-3804	232	43	be	be	AUX
fnp-3804	232	44	re	re	VERB
fnp-3804	232	45	-	-	VERB
fnp-3804	232	46	purposed	purposed	ADJ
fnp-3804	232	47	in	in	ADP
fnp-3804	232	48	order	order	NOUN
fnp-3804	232	49	to	to	PART
fnp-3804	232	50	improve	improve	VERB
fnp-3804	232	51	the	the	DET
fnp-3804	232	52	outcome	outcome	NOUN
fnp-3804	232	53	for	for	ADP
fnp-3804	232	54	patients	patient	NOUN
fnp-3804	232	55	with	with	ADP
fnp-3804	232	56	glioblastoma	glioblastoma	NOUN
fnp-3804	232	57	,	,	PUNCT
fnp-3804	232	58	e.g.	e.g.	ADV
fnp-3804	232	59	because	because	SCONJ
fnp-3804	232	60	they	they	PRON
fnp-3804	232	61	interfere	interfere	VERB
fnp-3804	232	62	with	with	ADP
fnp-3804	232	63	the	the	DET
fnp-3804	232	64	cell	cell	NOUN
fnp-3804	232	65	membranes	membrane	NOUN
fnp-3804	232	66	of	of	ADP
fnp-3804	232	67	the	the	DET
fnp-3804	232	68	tumor	tumor	NOUN
fnp-3804	232	69	cells	cell	NOUN
fnp-3804	232	70	(	(	PUNCT
fnp-3804	232	71	topic	topic	NOUN
fnp-3804	232	72	8)	8)	NUM
fnp-3804	232	73	.	.	PUNCT
fnp-3804	233	1	interestingly	interestingly	ADV
fnp-3804	233	2	,	,	PUNCT
fnp-3804	233	3	a	a	DET
fnp-3804	233	4	recent	recent	ADJ
fnp-3804	233	5	(	(	PUNCT
fnp-3804	233	6	‘	'	PUNCT
fnp-3804	233	7	seed	seed	NOUN
fnp-3804	233	8	&	&	CCONJ
fnp-3804	233	9	soil	soil	NOUN
fnp-3804	233	10	’	'	PUNCT
fnp-3804	233	11	)	)	PUNCT
fnp-3804	233	12	study	study	NOUN
fnp-3804	233	13	on	on	ADP
fnp-3804	233	14	the	the	DET
fnp-3804	233	15	metastatic	metastatic	ADJ
fnp-3804	233	16	potential	potential	NOUN
fnp-3804	233	17	of	of	ADP
fnp-3804	233	18	500	500	NUM
fnp-3804	233	19	human	human	ADJ
fnp-3804	233	20	cancer	cancer	NOUN
fnp-3804	233	21	cell	cell	NOUN
fnp-3804	233	22	lines	line	NOUN
fnp-3804	233	23	spanning	span	VERB
fnp-3804	233	24	21	21	NUM
fnp-3804	233	25	types	type	NOUN
fnp-3804	233	26	of	of	ADP
fnp-3804	233	27	solid	solid	ADJ
fnp-3804	233	28	tumor	tumor	NOUN
fnp-3804	233	29	,	,	PUNCT
fnp-3804	233	30	breast	breast	NOUN
fnp-3804	233	31	cancer	cancer	NOUN
fnp-3804	233	32	cells	cell	NOUN
fnp-3804	233	33	capable	capable	ADJ
fnp-3804	233	34	of	of	ADP
fnp-3804	233	35	metastasizing	metastasize	VERB
fnp-3804	233	36	to	to	ADP
fnp-3804	233	37	the	the	DET
fnp-3804	233	38	brain	brain	NOUN
fnp-3804	233	39	were	be	AUX
fnp-3804	233	40	found	find	VERB
fnp-3804	233	41	to	to	PART
fnp-3804	233	42	have	have	VERB
fnp-3804	233	43	an	an	DET
fnp-3804	233	44	altered	alter	VERB
fnp-3804	233	45	lipid	lipid	NOUN
fnp-3804	233	46	metabolism	metabolism	NOUN
fnp-3804	233	47	,	,	PUNCT
fnp-3804	233	48	perturbation	perturbation	NOUN
fnp-3804	233	49	of	of	ADP
fnp-3804	233	50	which	which	PRON
fnp-3804	233	51	indeed	indeed	ADV
fnp-3804	233	52	resulting	result	VERB
fnp-3804	233	53	in	in	ADP
fnp-3804	233	54	curbed	curbed	ADJ
fnp-3804	233	55	development	development	NOUN
fnp-3804	233	56	of	of	ADP
fnp-3804	233	57	brain	brain	NOUN
fnp-3804	233	58	metastasis	metastasis	NOUN
fnp-3804	233	59	40	40	NUM
fnp-3804	233	60	.	.	PUNCT
fnp-3804	234	1	as	as	SCONJ
fnp-3804	234	2	discussed	discuss	VERB
fnp-3804	234	3	under	under	ADP
fnp-3804	234	4	topic	topic	NOUN
fnp-3804	234	5	9	9	NUM
fnp-3804	234	6	,	,	PUNCT
fnp-3804	234	7	a	a	DET
fnp-3804	234	8	liquid	liquid	ADJ
fnp-3804	234	9	biopsy	biopsy	NOUN
fnp-3804	234	10	approach	approach	NOUN
fnp-3804	234	11	using	use	VERB
fnp-3804	234	12	detection	detection	NOUN
fnp-3804	234	13	of	of	ADP
fnp-3804	234	14	cnvs	cnvs	NOUN
fnp-3804	234	15	in	in	ADP
fnp-3804	234	16	csf	csf	ADJ
fnp-3804	234	17	-	-	PUNCT
fnp-3804	234	18	derived	derive	VERB
fnp-3804	234	19	cfdna	cfdna	NOUN
fnp-3804	234	20	may	may	AUX
fnp-3804	234	21	allow	allow	VERB
fnp-3804	234	22	for	for	ADP
fnp-3804	234	23	improved	improved	ADJ
fnp-3804	234	24	recognition	recognition	NOUN
fnp-3804	234	25	of	of	ADP
fnp-3804	234	26	disease	disease	NOUN
fnp-3804	234	27	progression	progression	NOUN
fnp-3804	234	28	in	in	ADP
fnp-3804	234	29	children	child	NOUN
fnp-3804	234	30	with	with	ADP
fnp-3804	234	31	medulloblastoma	medulloblastoma	NOUN
fnp-3804	234	32	.	.	PUNCT
fnp-3804	235	1	however	however	ADV
fnp-3804	235	2	,	,	PUNCT
fnp-3804	235	3	in	in	ADP
fnp-3804	235	4	a	a	DET
fnp-3804	235	5	very	very	ADV
fnp-3804	235	6	recent	recent	ADJ
fnp-3804	235	7	study	study	NOUN
fnp-3804	235	8	of	of	ADP
fnp-3804	235	9	258	258	NUM
fnp-3804	235	10	pediatric	pediatric	ADJ
fnp-3804	235	11	brain	brain	NOUN
fnp-3804	235	12	tumors	tumor	NOUN
fnp-3804	235	13	‘	'	PUNCT
fnp-3804	235	14	across	across	ADP
fnp-3804	235	15	all	all	DET
fnp-3804	235	16	histopathologies	histopathologie	NOUN
fnp-3804	235	17	’	'	PUNCT
fnp-3804	235	18	,	,	PUNCT
fnp-3804	235	19	cnvs	cnvs	NOUN
fnp-3804	235	20	were	be	AUX
fnp-3804	235	21	detected	detect	VERB
fnp-3804	235	22	in	in	ADP
fnp-3804	235	23	only	only	ADV
fnp-3804	235	24	20	20	NUM
fnp-3804	235	25	%	%	NOUN
fnp-3804	235	26	of	of	ADP
fnp-3804	235	27	csf	csf	ADJ
fnp-3804	235	28	-	-	PUNCT
fnp-3804	235	29	derived	derived	ADJ
fnp-3804	235	30	cfdna	cfdna	NOUN
fnp-3804	235	31	,	,	PUNCT
fnp-3804	235	32	and	and	CCONJ
fnp-3804	235	33	the	the	DET
fnp-3804	235	34	fact	fact	NOUN
fnp-3804	235	35	that	that	SCONJ
fnp-3804	235	36	no	no	DET
fnp-3804	235	37	genomic	genomic	ADJ
fnp-3804	235	38	aberrations	aberration	NOUN
fnp-3804	235	39	could	could	AUX
fnp-3804	235	40	be	be	AUX
fnp-3804	235	41	detected	detect	VERB
fnp-3804	235	42	in	in	ADP
fnp-3804	235	43	liquid	liquid	ADJ
fnp-3804	235	44	biopsies	biopsy	NOUN
fnp-3804	235	45	from	from	ADP
fnp-3804	235	46	patients	patient	NOUN
fnp-3804	235	47	with	with	ADP
fnp-3804	235	48	low	low	ADJ
fnp-3804	235	49	-	-	PUNCT
fnp-3804	235	50	grade	grade	NOUN
fnp-3804	235	51	gliomas	glioma	NOUN
fnp-3804	235	52	may	may	AUX
fnp-3804	235	53	indicate	indicate	VERB
fnp-3804	235	54	that	that	SCONJ
fnp-3804	235	55	its	its	PRON
fnp-3804	235	56	utility	utility	NOUN
fnp-3804	235	57	is	be	AUX
fnp-3804	235	58	more	more	ADV
fnp-3804	235	59	promising	promising	ADJ
fnp-3804	235	60	for	for	ADP
fnp-3804	235	61	patients	patient	NOUN
fnp-3804	235	62	with	with	ADP
fnp-3804	235	63	aggressive	aggressive	ADJ
fnp-3804	235	64	brain	brain	NOUN
fnp-3804	235	65	tumors	tumor	NOUN
fnp-3804	235	66	41	41	NUM
fnp-3804	235	67	.	.	PUNCT
fnp-3804	236	1	papers	paper	NOUN
fnp-3804	236	2	published	publish	VERB
fnp-3804	236	3	in	in	ADP
fnp-3804	236	4	2021	2021	NUM
fnp-3804	236	5	that	that	PRON
fnp-3804	236	6	the	the	DET
fnp-3804	236	7	authors	author	NOUN
fnp-3804	236	8	considered	consider	VERB
fnp-3804	236	9	as	as	ADP
fnp-3804	236	10	(	(	PUNCT
fnp-3804	236	11	very	very	ADV
fnp-3804	236	12	)	)	PUNCT
fnp-3804	236	13	interesting	interesting	ADJ
fnp-3804	236	14	,	,	PUNCT
fnp-3804	236	15	but	but	CCONJ
fnp-3804	236	16	that	that	PRON
fnp-3804	236	17	did	do	AUX
fnp-3804	236	18	n’t	not	PART
fnp-3804	236	19	make	make	VERB
fnp-3804	236	20	it	it	PRON
fnp-3804	236	21	to	to	ADP
fnp-3804	236	22	the	the	DET
fnp-3804	236	23	top	top	ADJ
fnp-3804	236	24	ten	ten	NUM
fnp-3804	236	25	list	list	NOUN
fnp-3804	236	26	include	include	VERB
fnp-3804	236	27	:	:	PUNCT
fnp-3804	236	28	publications	publication	NOUN
fnp-3804	236	29	presenting	present	VERB
fnp-3804	236	30	potential	potential	ADJ
fnp-3804	236	31	new	new	ADJ
fnp-3804	236	32	tumor	tumor	NOUN
fnp-3804	236	33	types	type	NOUN
fnp-3804	236	34	(	(	PUNCT
fnp-3804	236	35	e.g.	e.g.	ADV
fnp-3804	236	36	,	,	PUNCT
fnp-3804	236	37	supratentorial	supratentorial	ADJ
fnp-3804	236	38	neuroepithelial	neuroepithelial	ADJ
fnp-3804	236	39	tumors	tumor	NOUN
fnp-3804	236	40	,	,	PUNCT
fnp-3804	236	41	plagl1	plagl1	PROPN
fnp-3804	236	42	fusion	fusion	NOUN
fnp-3804	236	43	-	-	PUNCT
fnp-3804	236	44	positive	positive	ADJ
fnp-3804	236	45	42	42	NUM
fnp-3804	236	46	and	and	CCONJ
fnp-3804	236	47	histologically	histologically	ADV
fnp-3804	236	48	polyphenotypic	polyphenotypic	PROPN
fnp-3804	236	49	neuroepithelial	neuroepithelial	ADJ
fnp-3804	236	50	tumors	tumor	NOUN
fnp-3804	236	51	,	,	PUNCT
fnp-3804	236	52	patz1	patz1	PROPN
fnp-3804	236	53	fusion	fusion	NOUN
fnp-3804	236	54	-	-	PUNCT
fnp-3804	236	55	positive	positive	ADJ
fnp-3804	236	56	43	43	NUM
fnp-3804	236	57	)	)	PUNCT
fnp-3804	236	58	;	;	PUNCT
fnp-3804	236	59	the	the	DET
fnp-3804	236	60	report	report	NOUN
fnp-3804	236	61	of	of	ADP
fnp-3804	236	62	detailed	detailed	ADJ
fnp-3804	236	63	molecular	molecular	ADJ
fnp-3804	236	64	analysis	analysis	NOUN
fnp-3804	236	65	of	of	ADP
fnp-3804	236	66	(	(	PUNCT
fnp-3804	236	67	plus	plus	CCONJ
fnp-3804	236	68	clinical	clinical	ADJ
fnp-3804	236	69	variables	variable	NOUN
fnp-3804	236	70	in	in	ADP
fnp-3804	236	71	)	)	PUNCT
fnp-3804	236	72	a	a	DET
fnp-3804	236	73	series	series	NOUN
fnp-3804	236	74	of	of	ADP
fnp-3804	236	75	191	191	NUM
fnp-3804	236	76	medulloblastomas	medulloblastoma	NOUN
fnp-3804	236	77	in	in	ADP
fnp-3804	236	78	adults	adult	NOUN
fnp-3804	236	79	44	44	NUM
fnp-3804	236	80	;	;	PUNCT
fnp-3804	236	81	a	a	DET
fnp-3804	236	82	study	study	NOUN
fnp-3804	236	83	reporting	report	VERB
fnp-3804	236	84	that	that	SCONJ
fnp-3804	236	85	germline	germline	VERB
fnp-3804	236	86	variants	variant	NOUN
fnp-3804	236	87	in	in	ADP
fnp-3804	236	88	the	the	DET
fnp-3804	236	89	e	e	PROPN
fnp-3804	236	90	-	-	NOUN
fnp-3804	236	91	cadherin	cadherin	NOUN
fnp-3804	236	92	gene	gene	NOUN
fnp-3804	236	93	cdh1	cdh1	NOUN
fnp-3804	236	94	are	be	AUX
fnp-3804	236	95	(	(	PUNCT
fnp-3804	236	96	in	in	ADP
fnp-3804	236	97	addition	addition	NOUN
fnp-3804	236	98	to	to	ADP
fnp-3804	236	99	non	non	ADJ
fnp-3804	236	100	-	-	ADJ
fnp-3804	236	101	cns	cns	ADJ
fnp-3804	236	102	tumors	tumor	NOUN
fnp-3804	236	103	,	,	PUNCT
fnp-3804	236	104	especially	especially	ADV
fnp-3804	236	105	of	of	ADP
fnp-3804	236	106	the	the	DET
fnp-3804	236	107	stomach	stomach	NOUN
fnp-3804	236	108	and	and	CCONJ
fnp-3804	236	109	breast	breast	NOUN
fnp-3804	236	110	)	)	PUNCT
fnp-3804	236	111	associated	associate	VERB
fnp-3804	236	112	with	with	ADP
fnp-3804	236	113	increased	increase	VERB
fnp-3804	236	114	risk	risk	NOUN
fnp-3804	236	115	of	of	ADP
fnp-3804	236	116	neuroepithelial	neuroepithelial	ADJ
fnp-3804	236	117	tumors	tumor	NOUN
fnp-3804	236	118	/	/	SYM
fnp-3804	236	119	oligodendrogliomas	oligodendroglioma	NOUN
fnp-3804	236	120	,	,	PUNCT
fnp-3804	236	121	idh	idh	NOUN
fnp-3804	236	122	-	-	PUNCT
fnp-3804	236	123	mutant	mutant	NOUN
fnp-3804	236	124	,	,	PUNCT
fnp-3804	236	125	1p/19q	1p/19q	NOUN
fnp-3804	236	126	-	-	PUNCT
fnp-3804	236	127	codeleted	codelete	VERB
fnp-3804	236	128	45	45	NUM
fnp-3804	236	129	;	;	PUNCT
fnp-3804	236	130	papers	paper	NOUN
fnp-3804	236	131	reporting	report	VERB
fnp-3804	236	132	the	the	DET
fnp-3804	236	133	accuracy	accuracy	NOUN
fnp-3804	236	134	of	of	ADP
fnp-3804	236	135	different	different	ADJ
fnp-3804	236	136	molecular	molecular	ADJ
fnp-3804	236	137	tests	test	NOUN
fnp-3804	236	138	for	for	ADP
fnp-3804	236	139	assessment	assessment	NOUN
fnp-3804	236	140	1p/19q	1p/19q	PROPN
fnp-3804	236	141	status	status	NOUN
fnp-3804	236	142	46	46	NUM
fnp-3804	236	143	,	,	PUNCT
fnp-3804	236	144	and	and	CCONJ
fnp-3804	236	145	for	for	ADP
fnp-3804	236	146	mgmt	mgmt	NOUN
fnp-3804	236	147	promoter	promoter	NOUN
fnp-3804	236	148	methylation	methylation	NOUN
fnp-3804	236	149	status	status	NOUN
fnp-3804	236	150	47,48	47,48	NOUN
fnp-3804	236	151	.	.	PUNCT
fnp-3804	237	1	also	also	ADV
fnp-3804	237	2	,	,	PUNCT
fnp-3804	237	3	for	for	ADP
fnp-3804	237	4	those	those	PRON
fnp-3804	237	5	with	with	ADP
fnp-3804	237	6	a	a	DET
fnp-3804	237	7	keen	keen	ADJ
fnp-3804	237	8	interest	interest	NOUN
fnp-3804	237	9	in	in	ADP
fnp-3804	237	10	neuroimmunooncology	neuroimmunooncology	NOUN
fnp-3804	237	11	it	it	PRON
fnp-3804	237	12	may	may	AUX
fnp-3804	237	13	be	be	AUX
fnp-3804	237	14	good	good	ADJ
fnp-3804	237	15	to	to	PART
fnp-3804	237	16	know	know	VERB
fnp-3804	237	17	that	that	SCONJ
fnp-3804	237	18	dural	dural	ADJ
fnp-3804	237	19	sinuses	sinus	NOUN
fnp-3804	237	20	appear	appear	VERB
fnp-3804	237	21	to	to	PART
fnp-3804	237	22	act	act	VERB
fnp-3804	237	23	as	as	ADP
fnp-3804	237	24	a	a	DET
fnp-3804	237	25	‘	'	PUNCT
fnp-3804	237	26	neuroimmune	neuroimmune	ADJ
fnp-3804	237	27	interface	interface	NOUN
fnp-3804	237	28	’	'	PUNCT
fnp-3804	237	29	where	where	SCONJ
fnp-3804	237	30	brain	brain	NOUN
fnp-3804	237	31	antigens	antigen	NOUN
fnp-3804	237	32	are	be	AUX
fnp-3804	237	33	surveyed	survey	VERB
fnp-3804	237	34	,	,	PUNCT
fnp-3804	237	35	and	and	CCONJ
fnp-3804	237	36	that	that	PRON
fnp-3804	237	37	may	may	AUX
fnp-3804	237	38	show	show	VERB
fnp-3804	237	39	ageand	ageand	NOUN
fnp-3804	237	40	disease	disease	NOUN
fnp-3804	237	41	-	-	PUNCT
fnp-3804	237	42	related	relate	VERB
fnp-3804	237	43	dysfunction	dysfunction	NOUN
fnp-3804	237	44	50	50	NUM
fnp-3804	237	45	,	,	PUNCT
fnp-3804	237	46	and	and	CCONJ
fnp-3804	237	47	that	that	DET
fnp-3804	237	48	bone	bone	NOUN
fnp-3804	237	49	marrow	marrow	NOUN
fnp-3804	237	50	niches	niche	NOUN
fnp-3804	237	51	in	in	ADP
fnp-3804	237	52	the	the	DET
fnp-3804	237	53	skull	skull	NOUN
fnp-3804	237	54	and	and	CCONJ
fnp-3804	237	55	vertebral	vertebral	ADJ
fnp-3804	237	56	column	column	NOUN
fnp-3804	237	57	act	act	NOUN
fnp-3804	237	58	as	as	ADP
fnp-3804	237	59	myeloid	myeloid	NOUN
fnp-3804	237	60	cell	cell	NOUN
fnp-3804	237	61	reservoirs	reservoir	NOUN
fnp-3804	237	62	for	for	ADP
fnp-3804	237	63	the	the	DET
fnp-3804	237	64	meninges	meninge	NOUN
fnp-3804	237	65	and	and	CCONJ
fnp-3804	237	66	cns	cns	NOUN
fnp-3804	237	67	parenchyma	parenchyma	NOUN
fnp-3804	237	68	51	51	NUM
fnp-3804	237	69	.	.	PUNCT
fnp-3804	237	70	acknowledging	acknowledge	VERB
fnp-3804	237	71	that	that	SCONJ
fnp-3804	237	72	for	for	ADP
fnp-3804	237	73	multiple	multiple	ADJ
fnp-3804	237	74	decades	decade	NOUN
fnp-3804	237	75	histological	histological	ADJ
fnp-3804	237	76	slides	slide	NOUN
fnp-3804	237	77	formed	form	VERB
fnp-3804	237	78	the	the	DET
fnp-3804	237	79	basis	basis	NOUN
fnp-3804	237	80	for	for	ADP
fnp-3804	237	81	the	the	DET
fnp-3804	237	82	diagnosis	diagnosis	NOUN
fnp-3804	237	83	of	of	ADP
fnp-3804	237	84	(	(	PUNCT
fnp-3804	237	85	cns	cns	NOUN
fnp-3804	237	86	)	)	PUNCT
fnp-3804	237	87	tumors	tumor	NOUN
fnp-3804	237	88	,	,	PUNCT
fnp-3804	237	89	one	one	PRON
fnp-3804	237	90	can	can	AUX
fnp-3804	237	91	argue	argue	VERB
fnp-3804	237	92	that	that	SCONJ
fnp-3804	237	93	for	for	ADP
fnp-3804	237	94	a	a	DET
fnp-3804	237	95	long	long	ADJ
fnp-3804	237	96	time	time	NOUN
fnp-3804	237	97	clinical	clinical	ADJ
fnp-3804	237	98	(	(	PUNCT
fnp-3804	237	99	neuro)pathologists	neuro)pathologist	NOUN
fnp-3804	237	100	have	have	AUX
fnp-3804	237	101	acted	act	VERB
fnp-3804	237	102	as	as	ADP
fnp-3804	237	103	masters	master	NOUN
fnp-3804	237	104	of	of	ADP
fnp-3804	237	105	‘	'	PUNCT
fnp-3804	237	106	thin	thin	ADJ
fnp-3804	237	107	slicing	slicing	NOUN
fnp-3804	237	108	’	'	PUNCT
fnp-3804	237	109	(	(	PUNCT
fnp-3804	237	110	i.e.	i.e.	X
fnp-3804	237	111	,	,	PUNCT
fnp-3804	237	112	making	make	VERB
fnp-3804	237	113	quick	quick	ADJ
fnp-3804	237	114	inferences	inference	NOUN
fnp-3804	237	115	about	about	ADP
fnp-3804	237	116	characteristics	characteristic	NOUN
fnp-3804	237	117	of	of	ADP
fnp-3804	237	118	a	a	DET
fnp-3804	237	119	tumor	tumor	NOUN
fnp-3804	237	120	using	use	VERB
fnp-3804	237	121	a	a	DET
fnp-3804	237	122	limited	limited	ADJ
fnp-3804	237	123	amount	amount	NOUN
fnp-3804	237	124	of	of	ADP
fnp-3804	237	125	tissue	tissue	NOUN
fnp-3804	237	126	)	)	PUNCT
fnp-3804	237	127	.	.	PUNCT
fnp-3804	238	1	nowadays	nowadays	ADV
fnp-3804	238	2	,	,	PUNCT
fnp-3804	238	3	however	however	ADV
fnp-3804	238	4	,	,	PUNCT
fnp-3804	238	5	for	for	ADP
fnp-3804	238	6	the	the	DET
fnp-3804	238	7	pathological	pathological	ADJ
fnp-3804	238	8	diagnosis	diagnosis	NOUN
fnp-3804	238	9	of	of	ADP
fnp-3804	238	10	a	a	DET
fnp-3804	238	11	rapidly	rapidly	ADV
fnp-3804	238	12	increasing	increase	VERB
fnp-3804	238	13	number	number	NOUN
fnp-3804	238	14	of	of	ADP
fnp-3804	238	15	cns	cns	PROPN
fnp-3804	238	16	tumors	tumor	NOUN
fnp-3804	238	17	assessment	assessment	NOUN
fnp-3804	238	18	of	of	ADP
fnp-3804	238	19	particular	particular	ADJ
fnp-3804	238	20	molecular	molecular	ADJ
fnp-3804	238	21	characteristics	characteristic	NOUN
fnp-3804	238	22	is	be	AUX
fnp-3804	238	23	required	require	VERB
fnp-3804	238	24	as	as	ADV
fnp-3804	238	25	well	well	ADV
fnp-3804	238	26	.	.	PUNCT
fnp-3804	239	1	and	and	CCONJ
fnp-3804	239	2	in	in	ADP
fnp-3804	239	3	the	the	DET
fnp-3804	239	4	near	near	ADJ
fnp-3804	239	5	future	future	NOUN
fnp-3804	239	6	,	,	PUNCT
fnp-3804	239	7	spatial	spatial	ADJ
fnp-3804	239	8	and/or	and/or	CCONJ
fnp-3804	239	9	multi	multi	ADJ
fnp-3804	239	10	-	-	ADJ
fnp-3804	239	11	omics	omics	ADJ
fnp-3804	239	12	analysis	analysis	NOUN
fnp-3804	239	13	of	of	ADP
fnp-3804	239	14	these	these	DET
fnp-3804	239	15	tumors	tumor	NOUN
fnp-3804	239	16	may	may	AUX
fnp-3804	239	17	also	also	ADV
fnp-3804	239	18	be	be	AUX
fnp-3804	239	19	required	require	VERB
fnp-3804	239	20	.	.	PUNCT
fnp-3804	240	1	one	one	PRON
fnp-3804	240	2	can	can	AUX
fnp-3804	240	3	expect	expect	VERB
fnp-3804	240	4	that	that	SCONJ
fnp-3804	240	5	by	by	ADP
fnp-3804	240	6	that	that	DET
fnp-3804	240	7	time	time	NOUN
fnp-3804	240	8	,	,	PUNCT
fnp-3804	240	9	diagnostic	diagnostic	ADJ
fnp-3804	240	10	support	support	NOUN
fnp-3804	240	11	tools	tool	NOUN
fnp-3804	240	12	will	will	AUX
fnp-3804	240	13	become	become	VERB
fnp-3804	240	14	available	available	ADJ
fnp-3804	240	15	,	,	PUNCT
fnp-3804	240	16	such	such	ADJ
fnp-3804	240	17	as	as	ADP
fnp-3804	240	18	tools	tool	NOUN
fnp-3804	240	19	for	for	ADP
fnp-3804	240	20	artificial	artificial	ADJ
fnp-3804	240	21	intelligence	intelligence	NOUN
fnp-3804	240	22	(	(	PUNCT
fnp-3804	240	23	ai)-guided	ai)-guide	VERB
fnp-3804	240	24	analysis	analysis	NOUN
fnp-3804	240	25	of	of	ADP
fnp-3804	240	26	digitized	digitize	VERB
fnp-3804	240	27	,	,	PUNCT
fnp-3804	240	28	histological	histological	ADJ
fnp-3804	240	29	slides	slide	NOUN
fnp-3804	240	30	52	52	NUM
fnp-3804	240	31	,	,	PUNCT
fnp-3804	240	32	and	and	CCONJ
fnp-3804	240	33	visualization	visualization	NOUN
fnp-3804	240	34	tools	tool	NOUN
fnp-3804	240	35	for	for	ADP
fnp-3804	240	36	integration	integration	NOUN
fnp-3804	240	37	of	of	ADP
fnp-3804	240	38	the	the	DET
fnp-3804	240	39	multi	multi	ADJ
fnp-3804	240	40	-	-	ADJ
fnp-3804	240	41	omic	omic	ADJ
fnp-3804	240	42	profiling	profiling	NOUN
fnp-3804	240	43	data	datum	NOUN
fnp-3804	240	44	and	and	CCONJ
fnp-3804	240	45	for	for	ADP
fnp-3804	240	46	guidance	guidance	NOUN
fnp-3804	240	47	of	of	ADP
fnp-3804	240	48	therapeutic	therapeutic	ADJ
fnp-3804	240	49	decision	decision	NOUN
fnp-3804	240	50	-	-	PUNCT
fnp-3804	240	51	making	make	VERB
fnp-3804	240	52	39	39	NUM
fnp-3804	240	53	(	(	PUNCT
fnp-3804	240	54	figure	figure	NOUN
fnp-3804	240	55	3	3	NUM
fnp-3804	240	56	)	)	PUNCT
fnp-3804	240	57	.	.	PUNCT
fnp-3804	241	1	while	while	SCONJ
fnp-3804	241	2	such	such	DET
fnp-3804	241	3	a	a	DET
fnp-3804	241	4	transition	transition	NOUN
fnp-3804	241	5	from	from	ADP
fnp-3804	241	6	thin	thin	ADJ
fnp-3804	241	7	slicing	slicing	NOUN
fnp-3804	241	8	towards	towards	ADP
fnp-3804	241	9	augmented	augment	VERB
fnp-3804	241	10	reality	reality	NOUN
fnp-3804	241	11	indicates	indicate	VERB
fnp-3804	241	12	that	that	SCONJ
fnp-3804	241	13	the	the	DET
fnp-3804	241	14	future	future	NOUN
fnp-3804	241	15	of	of	ADP
fnp-3804	241	16	neurooncological	neurooncological	ADJ
fnp-3804	241	17	pathology	pathology	NOUN
fnp-3804	241	18	is	be	AUX
fnp-3804	241	19	bright	bright	ADJ
fnp-3804	241	20	,	,	PUNCT
fnp-3804	241	21	it	it	PRON
fnp-3804	241	22	would	would	AUX
fnp-3804	241	23	n’t	not	PART
fnp-3804	241	24	mean	mean	VERB
fnp-3804	241	25	too	too	ADV
fnp-3804	241	26	much	much	ADV
fnp-3804	241	27	unless	unless	SCONJ
fnp-3804	241	28	these	these	DET
fnp-3804	241	29	developments	development	NOUN
fnp-3804	241	30	indeed	indeed	ADV
fnp-3804	241	31	can	can	AUX
fnp-3804	241	32	help	help	VERB
fnp-3804	241	33	to	to	PART
fnp-3804	241	34	drastically	drastically	ADV
fnp-3804	241	35	improve	improve	VERB
fnp-3804	241	36	the	the	DET
fnp-3804	241	37	prognosis	prognosis	NOUN
fnp-3804	241	38	of	of	ADP
fnp-3804	241	39	patients	patient	NOUN
fnp-3804	241	40	that	that	PRON
fnp-3804	241	41	suffer	suffer	VERB
fnp-3804	241	42	from	from	ADP
fnp-3804	241	43	a	a	DET
fnp-3804	241	44	cns	cns	NOUN
fnp-3804	241	45	tumor	tumor	NOUN
fnp-3804	241	46	.	.	PUNCT
fnp-3804	242	1	figure	figure	VERB
fnp-3804	242	2	3	3	NUM
fnp-3804	242	3	.	.	PUNCT
fnp-3804	242	4	neurooncological	neurooncological	ADJ
fnp-3804	242	5	pathology	pathology	NOUN
fnp-3804	242	6	:	:	PUNCT
fnp-3804	242	7	from	from	ADP
fnp-3804	242	8	thin	thin	ADJ
fnp-3804	242	9	slicing	slicing	NOUN
fnp-3804	242	10	to	to	PART
fnp-3804	242	11	augmented	augment	VERB
fnp-3804	242	12	realityas	realityas	NOUN
fnp-3804	242	13	histological	histological	ADJ
fnp-3804	242	14	slides	slide	NOUN
fnp-3804	242	15	formed	form	VERB
fnp-3804	242	16	the	the	DET
fnp-3804	242	17	basis	basis	NOUN
fnp-3804	242	18	for	for	ADP
fnp-3804	242	19	the	the	DET
fnp-3804	242	20	diagnosis	diagnosis	NOUN
fnp-3804	242	21	of	of	ADP
fnp-3804	242	22	(	(	PUNCT
fnp-3804	242	23	cns	cns	NOUN
fnp-3804	242	24	)	)	PUNCT
fnp-3804	242	25	tumors	tumor	NOUN
fnp-3804	242	26	for	for	ADP
fnp-3804	242	27	multiple	multiple	ADJ
fnp-3804	242	28	decades	decade	NOUN
fnp-3804	242	29	,	,	PUNCT
fnp-3804	242	30	one	one	PRON
fnp-3804	242	31	can	can	AUX
fnp-3804	242	32	argue	argue	VERB
fnp-3804	242	33	that	that	SCONJ
fnp-3804	242	34	for	for	ADP
fnp-3804	242	35	a	a	DET
fnp-3804	242	36	long	long	ADJ
fnp-3804	242	37	time	time	NOUN
fnp-3804	242	38	clinical	clinical	ADJ
fnp-3804	242	39	(	(	PUNCT
fnp-3804	242	40	neuro)pathologists	neuro)pathologist	NOUN
fnp-3804	242	41	have	have	AUX
fnp-3804	242	42	acted	act	VERB
fnp-3804	242	43	as	as	ADP
fnp-3804	242	44	masters	master	NOUN
fnp-3804	242	45	of	of	ADP
fnp-3804	242	46	‘	'	PUNCT
fnp-3804	242	47	thin	thin	ADJ
fnp-3804	242	48	slicing	slicing	NOUN
fnp-3804	242	49	’	'	PUNCT
fnp-3804	242	50	.	.	PUNCT
fnp-3804	243	1	this	this	DET
fnp-3804	243	2	term	term	NOUN
fnp-3804	243	3	was	be	AUX
fnp-3804	243	4	initially	initially	ADV
fnp-3804	243	5	used	use	VERB
fnp-3804	243	6	especially	especially	ADV
fnp-3804	243	7	in	in	ADP
fnp-3804	243	8	psychology	psychology	NOUN
fnp-3804	243	9	and	and	CCONJ
fnp-3804	243	10	philosophy	philosophy	NOUN
fnp-3804	243	11	for	for	ADP
fnp-3804	243	12	a	a	DET
fnp-3804	243	13	situation	situation	NOUN
fnp-3804	243	14	in	in	ADP
fnp-3804	243	15	which	which	PRON
fnp-3804	243	16	one	one	PRON
fnp-3804	243	17	makes	make	VERB
fnp-3804	243	18	very	very	ADV
fnp-3804	243	19	quick	quick	ADJ
fnp-3804	243	20	inferences	inference	NOUN
fnp-3804	243	21	about	about	ADP
fnp-3804	243	22	the	the	DET
fnp-3804	243	23	state	state	NOUN
fnp-3804	243	24	,	,	PUNCT
fnp-3804	243	25	characteristics	characteristic	NOUN
fnp-3804	243	26	or	or	CCONJ
fnp-3804	243	27	details	detail	NOUN
fnp-3804	243	28	of	of	ADP
fnp-3804	243	29	an	an	DET
fnp-3804	243	30	individual	individual	NOUN
fnp-3804	243	31	or	or	CCONJ
fnp-3804	243	32	situation	situation	NOUN
fnp-3804	243	33	with	with	ADP
fnp-3804	243	34	minimal	minimal	ADJ
fnp-3804	243	35	amounts	amount	NOUN
fnp-3804	243	36	of	of	ADP
fnp-3804	243	37	information	information	NOUN
fnp-3804	243	38	.	.	PUNCT
fnp-3804	244	1	in	in	ADP
fnp-3804	244	2	the	the	DET
fnp-3804	244	3	context	context	NOUN
fnp-3804	244	4	of	of	ADP
fnp-3804	244	5	tumor	tumor	NOUN
fnp-3804	244	6	pathology	pathology	NOUN
fnp-3804	244	7	,	,	PUNCT
fnp-3804	244	8	it	it	PRON
fnp-3804	244	9	could	could	AUX
fnp-3804	244	10	literally	literally	ADV
fnp-3804	244	11	mean	mean	VERB
fnp-3804	244	12	the	the	DET
fnp-3804	244	13	ability	ability	NOUN
fnp-3804	244	14	to	to	PART
fnp-3804	244	15	make	make	VERB
fnp-3804	244	16	quick	quick	ADJ
fnp-3804	244	17	inferences	inference	NOUN
fnp-3804	244	18	about	about	ADP
fnp-3804	244	19	characteristics	characteristic	NOUN
fnp-3804	244	20	of	of	ADP
fnp-3804	244	21	a	a	DET
fnp-3804	244	22	tumor	tumor	NOUN
fnp-3804	244	23	using	use	VERB
fnp-3804	244	24	very	very	ADV
fnp-3804	244	25	thin	thin	ADJ
fnp-3804	244	26	slices	slice	NOUN
fnp-3804	244	27	of	of	ADP
fnp-3804	244	28	tissue	tissue	NOUN
fnp-3804	244	29	.	.	PUNCT
fnp-3804	245	1	nowadays	nowadays	ADV
fnp-3804	245	2	,	,	PUNCT
fnp-3804	245	3	however	however	ADV
fnp-3804	245	4	,	,	PUNCT
fnp-3804	245	5	for	for	ADP
fnp-3804	245	6	an	an	DET
fnp-3804	245	7	increasing	increase	VERB
fnp-3804	245	8	number	number	NOUN
fnp-3804	245	9	of	of	ADP
fnp-3804	245	10	cns	cns	NOUN
fnp-3804	245	11	tumors	tumor	NOUN
fnp-3804	245	12	,	,	PUNCT
fnp-3804	245	13	molecular	molecular	ADJ
fnp-3804	245	14	characterization	characterization	NOUN
fnp-3804	245	15	is	be	AUX
fnp-3804	245	16	necessary	necessary	ADJ
fnp-3804	245	17	as	as	ADV
fnp-3804	245	18	well	well	ADV
fnp-3804	245	19	.	.	PUNCT
fnp-3804	246	1	in	in	ADP
fnp-3804	246	2	the	the	DET
fnp-3804	246	3	near	near	ADJ
fnp-3804	246	4	future	future	NOUN
fnp-3804	246	5	,	,	PUNCT
fnp-3804	246	6	spatial	spatial	ADJ
fnp-3804	246	7	and/or	and/or	CCONJ
fnp-3804	246	8	multi	multi	ADJ
fnp-3804	246	9	-	-	ADJ
fnp-3804	246	10	omics	omics	ADJ
fnp-3804	246	11	analysis	analysis	NOUN
fnp-3804	246	12	of	of	ADP
fnp-3804	246	13	cns	cns	PROPN
fnp-3804	246	14	tumors	tumor	NOUN
fnp-3804	246	15	may	may	AUX
fnp-3804	246	16	be	be	AUX
fnp-3804	246	17	required	require	VERB
fnp-3804	246	18	for	for	ADP
fnp-3804	246	19	an	an	DET
fnp-3804	246	20	optimal	optimal	ADJ
fnp-3804	246	21	assessment	assessment	NOUN
fnp-3804	246	22	of	of	ADP
fnp-3804	246	23	the	the	DET
fnp-3804	246	24	diagnosis	diagnosis	NOUN
fnp-3804	246	25	(	(	PUNCT
fnp-3804	246	26	including	include	VERB
fnp-3804	246	27	prognosis	prognosis	NOUN
fnp-3804	246	28	)	)	PUNCT
fnp-3804	246	29	and	and	CCONJ
fnp-3804	246	30	for	for	ADP
fnp-3804	246	31	prediction	prediction	NOUN
fnp-3804	246	32	of	of	ADP
fnp-3804	246	33	the	the	DET
fnp-3804	246	34	best	good	ADJ
fnp-3804	246	35	therapeutic	therapeutic	ADJ
fnp-3804	246	36	management	management	NOUN
fnp-3804	246	37	.	.	PUNCT
fnp-3804	247	1	one	one	PRON
fnp-3804	247	2	can	can	AUX
fnp-3804	247	3	expect	expect	VERB
fnp-3804	247	4	that	that	SCONJ
fnp-3804	247	5	by	by	ADP
fnp-3804	247	6	that	that	DET
fnp-3804	247	7	time	time	NOUN
fnp-3804	247	8	,	,	PUNCT
fnp-3804	247	9	diagnostic	diagnostic	ADJ
fnp-3804	247	10	(	(	PUNCT
fnp-3804	247	11	ai	ai	AUX
fnp-3804	247	12	-	-	PUNCT
fnp-3804	247	13	guided	guide	VERB
fnp-3804	247	14	and	and	CCONJ
fnp-3804	247	15	visual	visual	ADJ
fnp-3804	247	16	)	)	PUNCT
fnp-3804	247	17	support	support	NOUN
fnp-3804	247	18	tools	tool	NOUN
fnp-3804	247	19	have	have	AUX
fnp-3804	247	20	become	become	VERB
fnp-3804	247	21	available	available	ADJ
fnp-3804	247	22	that	that	SCONJ
fnp-3804	247	23	guide	guide	VERB
fnp-3804	247	24	the	the	DET
fnp-3804	247	25	neurooncological	neurooncological	ADJ
fnp-3804	247	26	pathologist	pathologist	NOUN
fnp-3804	247	27	from	from	ADP
fnp-3804	247	28	a	a	DET
fnp-3804	247	29	more	more	ADV
fnp-3804	247	30	bounded	bounded	ADJ
fnp-3804	247	31	rationality	rationality	NOUN
fnp-3804	247	32	into	into	ADP
fnp-3804	247	33	an	an	DET
fnp-3804	247	34	augmented	augment	VERB
fnp-3804	247	35	reality	reality	NOUN
fnp-3804	247	36	.	.	PUNCT
fnp-3804	248	1	meanwhile	meanwhile	ADV
fnp-3804	248	2	,	,	PUNCT
fnp-3804	248	3	it	it	PRON
fnp-3804	248	4	is	be	AUX
fnp-3804	248	5	important	important	ADJ
fnp-3804	248	6	to	to	PART
fnp-3804	248	7	realize	realize	VERB
fnp-3804	248	8	that	that	SCONJ
fnp-3804	248	9	the	the	DET
fnp-3804	248	10	judgement	judgement	NOUN
fnp-3804	248	11	of	of	ADP
fnp-3804	248	12	an	an	DET
fnp-3804	248	13	experienced	experienced	ADJ
fnp-3804	248	14	(	(	PUNCT
fnp-3804	248	15	neuro)pathologist	neuro)pathologist	X
fnp-3804	248	16	based	base	VERB
fnp-3804	248	17	on	on	ADP
fnp-3804	248	18	thin	thin	ADJ
fnp-3804	248	19	-	-	PUNCT
fnp-3804	248	20	slicing	slicing	NOUN
fnp-3804	248	21	/	/	SYM
fnp-3804	248	22	histological	histological	ADJ
fnp-3804	248	23	slides	slide	NOUN
fnp-3804	248	24	will	will	AUX
fnp-3804	248	25	remain	remain	VERB
fnp-3804	248	26	invaluable	invaluable	ADJ
fnp-3804	248	27	for	for	ADP
fnp-3804	248	28	an	an	DET
fnp-3804	248	29	optimal	optimal	ADJ
fnp-3804	248	30	diagnosis	diagnosis	NOUN
fnp-3804	248	31	and	and	CCONJ
fnp-3804	248	32	indeed	indeed	ADV
fnp-3804	248	33	in	in	ADP
fnp-3804	248	34	quite	quite	DET
fnp-3804	248	35	some	some	DET
fnp-3804	248	36	situations	situation	NOUN
fnp-3804	248	37	(	(	PUNCT
fnp-3804	248	38	e.g.	e.g.	ADV
fnp-3804	248	39	,	,	PUNCT
fnp-3804	248	40	tumors	tumor	NOUN
fnp-3804	248	41	that	that	PRON
fnp-3804	248	42	can	can	AUX
fnp-3804	248	43	readily	readily	ADV
fnp-3804	248	44	be	be	AUX
fnp-3804	248	45	recognized	recognize	VERB
fnp-3804	248	46	based	base	VERB
fnp-3804	248	47	on	on	ADP
fnp-3804	248	48	an	an	DET
fnp-3804	248	49	h&e	h&e	PROPN
fnp-3804	248	50	stained	stain	VERB
fnp-3804	248	51	section	section	NOUN
fnp-3804	249	1	+	+	NOUN
fnp-3804	249	2	/some	/some	ADJ
fnp-3804	249	3	additional	additional	ADJ
fnp-3804	249	4	immunohistochemical	immunohistochemical	ADJ
fnp-3804	249	5	stains	stain	NOUN
fnp-3804	249	6	,	,	PUNCT
fnp-3804	249	7	and	and	CCONJ
fnp-3804	249	8	in	in	ADP
fnp-3804	249	9	case	case	NOUN
fnp-3804	249	10	of	of	ADP
fnp-3804	249	11	problems	problem	NOUN
fnp-3804	249	12	with	with	ADP
fnp-3804	249	13	representativeness	representativeness	NOUN
fnp-3804	249	14	or	or	CCONJ
fnp-3804	249	15	a	a	DET
fnp-3804	249	16	differential	differential	ADJ
fnp-3804	249	17	diagnosis	diagnosis	NOUN
fnp-3804	249	18	with	with	ADP
fnp-3804	249	19	non	non	ADJ
fnp-3804	249	20	-	-	ADJ
fnp-3804	249	21	neoplastic	neoplastic	ADJ
fnp-3804	249	22	lesions	lesion	NOUN
fnp-3804	249	23	)	)	PUNCT
fnp-3804	249	24	can	can	AUX
fnp-3804	249	25	even	even	ADV
fnp-3804	249	26	be	be	AUX
fnp-3804	249	27	more	more	ADV
fnp-3804	249	28	accurate	accurate	ADJ
fnp-3804	249	29	than	than	ADP
fnp-3804	249	30	judgements	judgement	NOUN
fnp-3804	249	31	based	base	VERB
fnp-3804	249	32	on	on	ADP
fnp-3804	249	33	much	much	ADV
fnp-3804	249	34	more	more	ADJ
fnp-3804	249	35	,	,	PUNCT
fnp-3804	249	36	non	non	ADJ
fnp-3804	249	37	-	-	ADJ
fnp-3804	249	38	histological	histological	ADJ
fnp-3804	249	39	information	information	NOUN
fnp-3804	249	40	.	.	PUNCT
fnp-3804	250	1	references	reference	NOUN
fnp-3804	250	2	louis	louis	PROPN
fnp-3804	250	3	dn	dn	PROPN
fnp-3804	250	4	,	,	PUNCT
fnp-3804	250	5	perry	perry	PROPN
fnp-3804	250	6	a	a	NOUN
fnp-3804	250	7	,	,	PUNCT
fnp-3804	250	8	wesseling	wessele	VERB
fnp-3804	250	9	p	p	NOUN
fnp-3804	250	10	,	,	PUNCT
fnp-3804	250	11	et	et	PROPN
fnp-3804	250	12	al	al	PROPN
fnp-3804	250	13	:	:	PUNCT
fnp-3804	250	14	the	the	DET
fnp-3804	250	15	2021	2021	NUM
fnp-3804	250	16	who	who	PRON
fnp-3804	250	17	classification	classification	NOUN
fnp-3804	250	18	of	of	ADP
fnp-3804	250	19	tumors	tumor	NOUN
fnp-3804	250	20	of	of	ADP
fnp-3804	250	21	the	the	DET
fnp-3804	250	22	central	central	ADJ
fnp-3804	250	23	nervous	nervous	ADJ
fnp-3804	250	24	system	system	NOUN
fnp-3804	250	25	:	:	PUNCT
fnp-3804	250	26	a	a	DET
fnp-3804	250	27	summary	summary	NOUN
fnp-3804	250	28	.	.	PUNCT
fnp-3804	251	1	neuro	neuro	PROPN
fnp-3804	251	2	oncol	oncol	PROPN
fnp-3804	251	3	23:1231	23:1231	PROPN
fnp-3804	251	4	-	-	SYM
fnp-3804	251	5	1251	1251	NUM
fnp-3804	251	6	,	,	PUNCT
fnp-3804	251	7	2021	2021	NUM
fnp-3804	251	8	ganz	ganz	PROPN
fnp-3804	251	9	j	j	PROPN
fnp-3804	251	10	,	,	PUNCT
fnp-3804	251	11	maury	maury	PROPN
fnp-3804	251	12	ea	ea	PROPN
fnp-3804	251	13	,	,	PUNCT
fnp-3804	251	14	becerra	becerra	PROPN
fnp-3804	251	15	b	b	PROPN
fnp-3804	251	16	,	,	PUNCT
fnp-3804	251	17	et	et	PROPN
fnp-3804	251	18	al	al	PROPN
fnp-3804	251	19	:	:	PUNCT
fnp-3804	251	20	rates	rate	NOUN
fnp-3804	251	21	and	and	CCONJ
fnp-3804	251	22	patterns	pattern	NOUN
fnp-3804	251	23	of	of	ADP
fnp-3804	251	24	clonal	clonal	ADJ
fnp-3804	251	25	oncogenic	oncogenic	ADJ
fnp-3804	251	26	mutations	mutation	NOUN
fnp-3804	251	27	in	in	ADP
fnp-3804	251	28	the	the	DET
fnp-3804	251	29	normal	normal	ADJ
fnp-3804	251	30	human	human	ADJ
fnp-3804	251	31	brain	brain	NOUN
fnp-3804	251	32	.	.	PUNCT
fnp-3804	252	1	cancer	cancer	NOUN
fnp-3804	252	2	discov	discov	PROPN
fnp-3804	252	3	12:172	12:172	NUM
fnp-3804	252	4	-	-	SYM
fnp-3804	252	5	185	185	NUM
fnp-3804	252	6	,	,	PUNCT
fnp-3804	252	7	2022	2022	NUM
fnp-3804	252	8	pan	pan	NOUN
fnp-3804	252	9	y	y	PROPN
fnp-3804	252	10	,	,	PUNCT
fnp-3804	252	11	hysinger	hysinger	PROPN
fnp-3804	252	12	jd	jd	PROPN
fnp-3804	252	13	,	,	PUNCT
fnp-3804	252	14	barron	barron	PROPN
fnp-3804	252	15	t	t	PROPN
fnp-3804	252	16	,	,	PUNCT
fnp-3804	252	17	et	et	PROPN
fnp-3804	252	18	al	al	PROPN
fnp-3804	252	19	:	:	PUNCT
fnp-3804	252	20	nf1	nf1	NOUN
fnp-3804	252	21	mutation	mutation	NOUN
fnp-3804	252	22	drives	drive	VERB
fnp-3804	252	23	neuronal	neuronal	ADJ
fnp-3804	252	24	activity	activity	NOUN
fnp-3804	252	25	-	-	PUNCT
fnp-3804	252	26	dependent	dependent	ADJ
fnp-3804	252	27	initiation	initiation	NOUN
fnp-3804	252	28	of	of	ADP
fnp-3804	252	29	optic	optic	ADJ
fnp-3804	252	30	glioma	glioma	NOUN
fnp-3804	252	31	.	.	PUNCT
fnp-3804	253	1	nature	nature	NOUN
fnp-3804	253	2	594:277	594:277	PROPN
fnp-3804	253	3	-	-	PUNCT
fnp-3804	253	4	282	282	NUM
fnp-3804	253	5	,	,	PUNCT
fnp-3804	253	6	2021	2021	NUM
fnp-3804	253	7	haag	haag	PROPN
fnp-3804	253	8	d	d	PROPN
fnp-3804	253	9	,	,	PUNCT
fnp-3804	253	10	mack	mack	PROPN
fnp-3804	253	11	n	n	CCONJ
fnp-3804	253	12	,	,	PUNCT
fnp-3804	253	13	benites	benite	VERB
fnp-3804	253	14	goncalves	goncalves	PROPN
fnp-3804	253	15	da	da	PROPN
fnp-3804	253	16	silva	silva	PROPN
fnp-3804	253	17	p	p	PROPN
fnp-3804	253	18	,	,	PUNCT
fnp-3804	253	19	et	et	PROPN
fnp-3804	253	20	al	al	PROPN
fnp-3804	253	21	:	:	PUNCT
fnp-3804	253	22	h3.3	h3.3	NOUN
fnp-3804	253	23	-	-	PUNCT
fnp-3804	253	24	k27	k27	NOUN
fnp-3804	253	25	m	m	NOUN
fnp-3804	253	26	drives	drive	VERB
fnp-3804	253	27	neural	neural	ADJ
fnp-3804	253	28	stem	stem	NOUN
fnp-3804	253	29	cell	cell	NOUN
fnp-3804	253	30	-	-	PUNCT
fnp-3804	253	31	specific	specific	ADJ
fnp-3804	253	32	gliomagenesis	gliomagenesis	NOUN
fnp-3804	253	33	in	in	ADP
fnp-3804	253	34	a	a	DET
fnp-3804	253	35	human	human	ADJ
fnp-3804	253	36	ipsc	ipsc	NOUN
fnp-3804	253	37	-	-	PUNCT
fnp-3804	253	38	derived	derive	VERB
fnp-3804	253	39	model	model	NOUN
fnp-3804	253	40	.	.	PUNCT
fnp-3804	254	1	cancer	cancer	NOUN
fnp-3804	254	2	cell	cell	NOUN
fnp-3804	254	3	39:407	39:407	NUM
fnp-3804	254	4	-	-	SYM
fnp-3804	254	5	422	422	NUM
fnp-3804	254	6	e13	e13	NOUN
fnp-3804	254	7	,	,	PUNCT
fnp-3804	254	8	2021	2021	NUM
fnp-3804	254	9	bressan	bressan	NOUN
fnp-3804	254	10	rb	rb	PROPN
fnp-3804	254	11	,	,	PUNCT
fnp-3804	254	12	southgate	southgate	PROPN
fnp-3804	254	13	b	b	PROPN
fnp-3804	254	14	,	,	PUNCT
fnp-3804	254	15	ferguson	ferguson	PROPN
fnp-3804	254	16	km	km	PROPN
fnp-3804	254	17	,	,	PUNCT
fnp-3804	254	18	et	et	PROPN
fnp-3804	254	19	al	al	PROPN
fnp-3804	254	20	:	:	PUNCT
fnp-3804	254	21	regional	regional	ADJ
fnp-3804	254	22	identity	identity	NOUN
fnp-3804	254	23	of	of	ADP
fnp-3804	254	24	human	human	ADJ
fnp-3804	254	25	neural	neural	ADJ
fnp-3804	254	26	stem	stem	NOUN
fnp-3804	254	27	cells	cell	NOUN
fnp-3804	254	28	determines	determine	VERB
fnp-3804	254	29	oncogenic	oncogenic	ADJ
fnp-3804	254	30	responses	response	NOUN
fnp-3804	254	31	to	to	ADP
fnp-3804	254	32	histone	histone	NOUN
fnp-3804	254	33	h3.3	h3.3	NOUN
fnp-3804	254	34	mutants	mutant	NOUN
fnp-3804	254	35	.	.	PUNCT
fnp-3804	255	1	cell	cell	NOUN
fnp-3804	255	2	stem	stem	NOUN
fnp-3804	255	3	cell	cell	NOUN
fnp-3804	255	4	28:877	28:877	NUM
fnp-3804	255	5	-	-	PUNCT
fnp-3804	255	6	893	893	NUM
fnp-3804	255	7	e9	e9	NOUN
fnp-3804	255	8	,	,	PUNCT
fnp-3804	255	9	2021	2021	NUM
fnp-3804	255	10	johnson	johnson	PROPN
fnp-3804	255	11	kc	kc	PROPN
fnp-3804	255	12	,	,	PUNCT
fnp-3804	255	13	anderson	anderson	PROPN
fnp-3804	255	14	kj	kj	PROPN
fnp-3804	255	15	,	,	PUNCT
fnp-3804	255	16	courtois	courtois	PROPN
fnp-3804	255	17	et	et	PROPN
fnp-3804	255	18	,	,	PUNCT
fnp-3804	255	19	et	et	PROPN
fnp-3804	255	20	al	al	PROPN
fnp-3804	255	21	:	:	PUNCT
fnp-3804	255	22	single	single	ADJ
fnp-3804	255	23	-	-	PUNCT
fnp-3804	255	24	cell	cell	NOUN
fnp-3804	255	25	multimodal	multimodal	NOUN
fnp-3804	255	26	glioma	glioma	NOUN
fnp-3804	255	27	analyses	analysis	NOUN
fnp-3804	255	28	identify	identify	VERB
fnp-3804	255	29	epigenetic	epigenetic	ADJ
fnp-3804	255	30	regulators	regulator	NOUN
fnp-3804	255	31	of	of	ADP
fnp-3804	255	32	cellular	cellular	ADJ
fnp-3804	255	33	plasticity	plasticity	NOUN
fnp-3804	255	34	and	and	CCONJ
fnp-3804	255	35	environmental	environmental	ADJ
fnp-3804	255	36	stress	stress	NOUN
fnp-3804	255	37	response	response	NOUN
fnp-3804	255	38	.	.	PUNCT
fnp-3804	256	1	nat	nat	PROPN
fnp-3804	256	2	genet	genet	PROPN
fnp-3804	256	3	53:1456	53:1456	PROPN
fnp-3804	256	4	-	-	SYM
fnp-3804	256	5	1468	1468	NUM
fnp-3804	256	6	,	,	PUNCT
fnp-3804	256	7	2021	2021	NUM
fnp-3804	256	8	chaligne	chaligne	NOUN
fnp-3804	256	9	r	r	NOUN
fnp-3804	256	10	,	,	PUNCT
fnp-3804	256	11	gaiti	gaiti	NOUN
fnp-3804	256	12	f	f	PROPN
fnp-3804	256	13	,	,	PUNCT
fnp-3804	256	14	silverbush	silverbush	NOUN
fnp-3804	256	15	d	d	PROPN
fnp-3804	256	16	,	,	PUNCT
fnp-3804	256	17	et	et	PROPN
fnp-3804	256	18	al	al	PROPN
fnp-3804	256	19	:	:	PUNCT
fnp-3804	256	20	epigenetic	epigenetic	ADJ
fnp-3804	256	21	encoding	encoding	NOUN
fnp-3804	256	22	,	,	PUNCT
fnp-3804	256	23	heritability	heritability	NOUN
fnp-3804	256	24	and	and	CCONJ
fnp-3804	256	25	plasticity	plasticity	NOUN
fnp-3804	256	26	of	of	ADP
fnp-3804	256	27	glioma	glioma	ADJ
fnp-3804	256	28	transcriptional	transcriptional	NOUN
fnp-3804	256	29	cell	cell	NOUN
fnp-3804	256	30	states	state	NOUN
fnp-3804	256	31	.	.	PUNCT
fnp-3804	257	1	nat	nat	PROPN
fnp-3804	257	2	genet	genet	PROPN
fnp-3804	257	3	53:1469	53:1469	NOUN
fnp-3804	257	4	-	-	SYM
fnp-3804	257	5	1479	1479	NUM
fnp-3804	257	6	,	,	PUNCT
fnp-3804	257	7	2021	2021	NUM
fnp-3804	257	8	wang	wang	PROPN
fnp-3804	257	9	lb	lb	PROPN
fnp-3804	257	10	,	,	PUNCT
fnp-3804	257	11	karpova	karpova	PROPN
fnp-3804	257	12	a	a	PRON
fnp-3804	257	13	,	,	PUNCT
fnp-3804	257	14	gritsenko	gritsenko	PROPN
fnp-3804	257	15	ma	ma	PROPN
fnp-3804	257	16	,	,	PUNCT
fnp-3804	257	17	et	et	PROPN
fnp-3804	257	18	al	al	PROPN
fnp-3804	257	19	:	:	PUNCT
fnp-3804	257	20	proteogenomic	proteogenomic	ADJ
fnp-3804	257	21	and	and	CCONJ
fnp-3804	257	22	metabolomic	metabolomic	ADJ
fnp-3804	257	23	characterization	characterization	NOUN
fnp-3804	257	24	of	of	ADP
fnp-3804	257	25	human	human	ADJ
fnp-3804	257	26	glioblastoma	glioblastoma	NOUN
fnp-3804	257	27	.	.	PUNCT
fnp-3804	258	1	cancer	cancer	NOUN
fnp-3804	258	2	cell	cell	NOUN
fnp-3804	258	3	39:509	39:509	NUM
fnp-3804	258	4	-	-	SYM
fnp-3804	258	5	528	528	NUM
fnp-3804	258	6	e20	e20	NOUN
fnp-3804	258	7	,	,	PUNCT
fnp-3804	258	8	2021	2021	NUM
fnp-3804	258	9	schaettler	schaettler	NOUN
fnp-3804	258	10	mo	mo	PROPN
fnp-3804	258	11	,	,	PUNCT
fnp-3804	258	12	richters	richter	NOUN
fnp-3804	258	13	mm	mm	PROPN
fnp-3804	258	14	,	,	PUNCT
fnp-3804	258	15	wang	wang	PROPN
fnp-3804	258	16	az	az	PROPN
fnp-3804	258	17	,	,	PUNCT
fnp-3804	258	18	et	et	PROPN
fnp-3804	258	19	al	al	PROPN
fnp-3804	258	20	:	:	PUNCT
fnp-3804	258	21	characterization	characterization	NOUN
fnp-3804	258	22	of	of	ADP
fnp-3804	258	23	the	the	DET
fnp-3804	258	24	genomic	genomic	NOUN
fnp-3804	258	25	and	and	CCONJ
fnp-3804	258	26	immunologic	immunologic	ADJ
fnp-3804	258	27	diversity	diversity	NOUN
fnp-3804	258	28	of	of	ADP
fnp-3804	258	29	malignant	malignant	ADJ
fnp-3804	258	30	brain	brain	NOUN
fnp-3804	258	31	tumors	tumor	NOUN
fnp-3804	258	32	through	through	ADP
fnp-3804	258	33	multisector	multisector	NOUN
fnp-3804	258	34	analysis	analysis	NOUN
fnp-3804	258	35	.	.	PUNCT
fnp-3804	259	1	cancer	cancer	NOUN
fnp-3804	259	2	discov	discov	PROPN
fnp-3804	259	3	12:154	12:154	NUM
fnp-3804	259	4	-	-	SYM
fnp-3804	259	5	171	171	NUM
fnp-3804	259	6	,	,	PUNCT
fnp-3804	259	7	2022	2022	NUM
fnp-3804	259	8	bi	bi	PROPN
fnp-3804	259	9	j	j	PROPN
fnp-3804	259	10	,	,	PUNCT
fnp-3804	259	11	khan	khan	PROPN
fnp-3804	259	12	a	a	PRON
fnp-3804	259	13	,	,	PUNCT
fnp-3804	259	14	tang	tang	PROPN
fnp-3804	259	15	j	j	PROPN
fnp-3804	259	16	,	,	PUNCT
fnp-3804	259	17	et	et	PROPN
fnp-3804	259	18	al	al	PROPN
fnp-3804	259	19	:	:	PUNCT
fnp-3804	259	20	targeting	target	VERB
fnp-3804	259	21	glioblastoma	glioblastoma	NOUN
fnp-3804	259	22	signaling	signal	VERB
fnp-3804	259	23	and	and	CCONJ
fnp-3804	259	24	metabolism	metabolism	NOUN
fnp-3804	259	25	with	with	ADP
fnp-3804	259	26	a	a	DET
fnp-3804	259	27	re	re	ADJ
fnp-3804	259	28	-	-	ADJ
fnp-3804	259	29	purposed	purposed	ADJ
fnp-3804	259	30	brain	brain	NOUN
fnp-3804	259	31	-	-	PUNCT
fnp-3804	259	32	penetrant	penetrant	NOUN
fnp-3804	259	33	drug	drug	NOUN
fnp-3804	259	34	.	.	PUNCT
fnp-3804	260	1	cell	cell	NOUN
fnp-3804	260	2	rep	rep	PROPN
fnp-3804	260	3	37:109957	37:109957	NOUN
fnp-3804	260	4	,	,	PUNCT
fnp-3804	260	5	2021	2021	NUM
fnp-3804	260	6	liu	liu	PROPN
fnp-3804	260	7	apy	apy	PROPN
fnp-3804	260	8	,	,	PUNCT
fnp-3804	260	9	smith	smith	PROPN
fnp-3804	260	10	ks	ks	PROPN
fnp-3804	260	11	,	,	PUNCT
fnp-3804	260	12	kumar	kumar	PROPN
fnp-3804	260	13	r	r	PROPN
fnp-3804	260	14	,	,	PUNCT
fnp-3804	260	15	et	et	PROPN
fnp-3804	260	16	al	al	PROPN
fnp-3804	260	17	:	:	PUNCT
fnp-3804	260	18	serial	serial	ADJ
fnp-3804	260	19	assessment	assessment	NOUN
fnp-3804	260	20	of	of	ADP
fnp-3804	260	21	measurable	measurable	ADJ
fnp-3804	260	22	residual	residual	ADJ
fnp-3804	260	23	disease	disease	NOUN
fnp-3804	260	24	in	in	ADP
fnp-3804	260	25	medulloblastoma	medulloblastoma	ADJ
fnp-3804	260	26	liquid	liquid	ADJ
fnp-3804	260	27	biopsies	biopsy	NOUN
fnp-3804	260	28	.	.	PUNCT
fnp-3804	261	1	cancer	cancer	NOUN
fnp-3804	261	2	cell	cell	NOUN
fnp-3804	261	3	39:1519	39:1519	NUM
fnp-3804	261	4	-	-	SYM
fnp-3804	261	5	1530	1530	NUM
fnp-3804	261	6	e4	e4	PROPN
fnp-3804	261	7	,	,	PUNCT
fnp-3804	261	8	2021	2021	NUM
fnp-3804	261	9	nassiri	nassiri	NOUN
fnp-3804	261	10	f	f	PROPN
fnp-3804	261	11	,	,	PUNCT
fnp-3804	261	12	liu	liu	PROPN
fnp-3804	261	13	j	j	PROPN
fnp-3804	261	14	,	,	PUNCT
fnp-3804	261	15	patil	patil	PROPN
fnp-3804	261	16	v	v	PROPN
fnp-3804	261	17	,	,	PUNCT
fnp-3804	261	18	et	et	PROPN
fnp-3804	261	19	al	al	PROPN
fnp-3804	261	20	:	:	PUNCT
fnp-3804	261	21	a	a	DET
fnp-3804	261	22	clinically	clinically	ADV
fnp-3804	261	23	applicable	applicable	ADJ
fnp-3804	261	24	integrative	integrative	ADJ
fnp-3804	261	25	molecular	molecular	ADJ
fnp-3804	261	26	classification	classification	NOUN
fnp-3804	261	27	of	of	ADP
fnp-3804	261	28	meningiomas	meningioma	NOUN
fnp-3804	261	29	.	.	PUNCT
fnp-3804	262	1	nature	nature	NOUN
fnp-3804	262	2	597:119	597:119	PROPN
fnp-3804	262	3	-	-	PUNCT
fnp-3804	262	4	125	125	NUM
fnp-3804	262	5	,	,	PUNCT
fnp-3804	262	6	2021	2021	NUM
fnp-3804	262	7	maas	maas	PROPN
fnp-3804	262	8	sln	sln	PROPN
fnp-3804	262	9	,	,	PUNCT
fnp-3804	262	10	stichel	stichel	PROPN
fnp-3804	262	11	d	d	PROPN
fnp-3804	262	12	,	,	PUNCT
fnp-3804	262	13	hielscher	hielscher	PROPN
fnp-3804	262	14	t	t	PROPN
fnp-3804	262	15	,	,	PUNCT
fnp-3804	262	16	et	et	PROPN
fnp-3804	262	17	al	al	PROPN
fnp-3804	262	18	:	:	PUNCT
fnp-3804	262	19	integrated	integrate	VERB
fnp-3804	262	20	molecular	molecular	ADJ
fnp-3804	262	21	-	-	PUNCT
fnp-3804	262	22	morphologic	morphologic	ADJ
fnp-3804	262	23	meningioma	meningioma	NOUN
fnp-3804	262	24	classification	classification	NOUN
fnp-3804	262	25	:	:	PUNCT
fnp-3804	262	26	a	a	DET
fnp-3804	262	27	multicenter	multicenter	ADJ
fnp-3804	262	28	retrospective	retrospective	ADJ
fnp-3804	262	29	analysis	analysis	NOUN
fnp-3804	262	30	,	,	PUNCT
fnp-3804	262	31	retrospectively	retrospectively	ADV
fnp-3804	262	32	and	and	CCONJ
fnp-3804	262	33	prospectively	prospectively	ADV
fnp-3804	262	34	validated	validate	VERB
fnp-3804	262	35	.	.	PUNCT
fnp-3804	263	1	j	j	PROPN
fnp-3804	263	2	clin	clin	PROPN
fnp-3804	263	3	oncol	oncol	PROPN
fnp-3804	263	4	39:3839	39:3839	PROPN
fnp-3804	263	5	-	-	SYM
fnp-3804	263	6	3852	3852	NUM
fnp-3804	263	7	,	,	PUNCT
fnp-3804	263	8	2021	2021	NUM
fnp-3804	263	9	driver	driver	NOUN
fnp-3804	263	10	j	j	PROPN
fnp-3804	263	11	,	,	PUNCT
fnp-3804	263	12	hoffman	hoffman	PROPN
fnp-3804	263	13	se	se	PROPN
fnp-3804	263	14	,	,	PUNCT
fnp-3804	263	15	tavakol	tavakol	PROPN
fnp-3804	263	16	s	s	PART
fnp-3804	263	17	,	,	PUNCT
fnp-3804	263	18	et	et	PROPN
fnp-3804	263	19	al	al	PROPN
fnp-3804	263	20	:	:	PUNCT
fnp-3804	263	21	a	a	DET
fnp-3804	263	22	molecularly	molecularly	ADV
fnp-3804	263	23	integrated	integrate	VERB
fnp-3804	263	24	grade	grade	NOUN
fnp-3804	263	25	for	for	ADP
fnp-3804	263	26	meningioma	meningioma	NOUN
fnp-3804	263	27	.	.	PUNCT
fnp-3804	264	1	neuro	neuro	PROPN
fnp-3804	264	2	oncol	oncol	PROPN
fnp-3804	264	3	,	,	PUNCT
fnp-3804	264	4	2021	2021	NUM
fnp-3804	264	5	louis	louis	PROPN
fnp-3804	264	6	dn	dn	PROPN
fnp-3804	264	7	,	,	PUNCT
fnp-3804	264	8	wesseling	wessele	VERB
fnp-3804	264	9	p	p	NOUN
fnp-3804	264	10	,	,	PUNCT
fnp-3804	264	11	aldape	aldape	NOUN
fnp-3804	264	12	k	k	PROPN
fnp-3804	264	13	,	,	PUNCT
fnp-3804	264	14	et	et	PROPN
fnp-3804	264	15	al	al	PROPN
fnp-3804	264	16	:	:	PUNCT
fnp-3804	264	17	cimpact	cimpact	ADJ
fnp-3804	264	18	-	-	PUNCT
fnp-3804	264	19	now	now	ADV
fnp-3804	264	20	update	update	NOUN
fnp-3804	264	21	6	6	NUM
fnp-3804	264	22	:	:	PUNCT
fnp-3804	264	23	new	new	ADJ
fnp-3804	264	24	entity	entity	NOUN
fnp-3804	264	25	and	and	CCONJ
fnp-3804	264	26	diagnostic	diagnostic	ADJ
fnp-3804	264	27	principle	principle	ADJ
fnp-3804	264	28	recommendations	recommendation	NOUN
fnp-3804	264	29	of	of	ADP
fnp-3804	264	30	the	the	DET
fnp-3804	264	31	cimpact	cimpact	ADJ
fnp-3804	264	32	-	-	PUNCT
fnp-3804	264	33	utrecht	utrecht	NOUN
fnp-3804	264	34	meeting	meeting	NOUN
fnp-3804	264	35	on	on	ADP
fnp-3804	264	36	future	future	ADJ
fnp-3804	264	37	cns	cns	NOUN
fnp-3804	264	38	tumor	tumor	NOUN
fnp-3804	264	39	classification	classification	NOUN
fnp-3804	264	40	and	and	CCONJ
fnp-3804	264	41	grading	grade	VERB
fnp-3804	264	42	.	.	PUNCT
fnp-3804	265	1	brain	brain	NOUN
fnp-3804	265	2	pathol	pathol	NOUN
fnp-3804	265	3	30:844	30:844	NUM
fnp-3804	265	4	-	-	SYM
fnp-3804	265	5	856	856	NUM
fnp-3804	265	6	,	,	PUNCT
fnp-3804	265	7	2020	2020	NUM
fnp-3804	265	8	martincorena	martincorena	VERB
fnp-3804	265	9	i	i	PRON
fnp-3804	265	10	:	:	PUNCT
fnp-3804	265	11	somatic	somatic	ADJ
fnp-3804	265	12	mutation	mutation	NOUN
fnp-3804	265	13	and	and	CCONJ
fnp-3804	265	14	clonal	clonal	ADJ
fnp-3804	265	15	expansions	expansion	NOUN
fnp-3804	265	16	in	in	ADP
fnp-3804	265	17	human	human	ADJ
fnp-3804	265	18	tissues	tissue	NOUN
fnp-3804	265	19	.	.	PUNCT
fnp-3804	266	1	genome	genome	NOUN
fnp-3804	266	2	med	me	VERB
fnp-3804	266	3	11:35	11:35	NUM
fnp-3804	266	4	,	,	PUNCT
fnp-3804	266	5	2019	2019	NUM
fnp-3804	266	6	barthel	barthel	PROPN
fnp-3804	266	7	fp	fp	NOUN
fnp-3804	266	8	,	,	PUNCT
fnp-3804	266	9	wesseling	wessele	VERB
fnp-3804	266	10	p	p	NOUN
fnp-3804	266	11	,	,	PUNCT
fnp-3804	266	12	verhaak	verhaak	NOUN
fnp-3804	266	13	rgw	rgw	NOUN
fnp-3804	266	14	:	:	PUNCT
fnp-3804	266	15	reconstructing	reconstruct	VERB
fnp-3804	266	16	the	the	DET
fnp-3804	266	17	molecular	molecular	ADJ
fnp-3804	266	18	life	life	NOUN
fnp-3804	266	19	history	history	NOUN
fnp-3804	266	20	of	of	ADP
fnp-3804	266	21	gliomas	glioma	NOUN
fnp-3804	266	22	.	.	PUNCT
fnp-3804	267	1	acta	acta	PROPN
fnp-3804	267	2	neuropathol	neuropathol	PROPN
fnp-3804	267	3	135:649	135:649	PROPN
fnp-3804	267	4	-	-	SYM
fnp-3804	267	5	670	670	NUM
fnp-3804	267	6	,	,	PUNCT
fnp-3804	267	7	2018	2018	NUM
fnp-3804	267	8	barresi	barresi	NOUN
fnp-3804	267	9	v	v	NOUN
fnp-3804	267	10	,	,	PUNCT
fnp-3804	267	11	lionti	lionti	PROPN
fnp-3804	267	12	s	s	PROPN
fnp-3804	267	13	,	,	PUNCT
fnp-3804	267	14	valori	valori	PROPN
fnp-3804	267	15	l	l	PROPN
fnp-3804	267	16	,	,	PUNCT
fnp-3804	267	17	et	et	PROPN
fnp-3804	267	18	al	al	PROPN
fnp-3804	267	19	:	:	PUNCT
fnp-3804	267	20	dual	dual	ADJ
fnp-3804	267	21	-	-	PUNCT
fnp-3804	267	22	genotype	genotype	NOUN
fnp-3804	267	23	diffuse	diffuse	NOUN
fnp-3804	267	24	low	low	ADJ
fnp-3804	267	25	-	-	PUNCT
fnp-3804	267	26	grade	grade	NOUN
fnp-3804	267	27	glioma	glioma	NOUN
fnp-3804	267	28	:	:	PUNCT
fnp-3804	267	29	is	be	AUX
fnp-3804	267	30	it	it	PRON
fnp-3804	267	31	really	really	ADV
fnp-3804	267	32	time	time	NOUN
fnp-3804	267	33	to	to	PART
fnp-3804	267	34	abandon	abandon	VERB
fnp-3804	267	35	oligoastrocytoma	oligoastrocytoma	NOUN
fnp-3804	267	36	as	as	ADP
fnp-3804	267	37	a	a	DET
fnp-3804	267	38	distinct	distinct	ADJ
fnp-3804	267	39	entity	entity	NOUN
fnp-3804	267	40	?	?	PUNCT
fnp-3804	268	1	j	j	PROPN
fnp-3804	268	2	neuropathol	neuropathol	PROPN
fnp-3804	268	3	exp	exp	PROPN
fnp-3804	268	4	neurol	neurol	PROPN
fnp-3804	268	5	76:342	76:342	PROPN
fnp-3804	268	6	-	-	SYM
fnp-3804	268	7	346	346	NUM
fnp-3804	268	8	,	,	PUNCT
fnp-3804	268	9	2017	2017	NUM
fnp-3804	268	10	venkatesh	venkatesh	PROPN
fnp-3804	268	11	hs	hs	PROPN
fnp-3804	268	12	,	,	PUNCT
fnp-3804	268	13	morishita	morishita	PROPN
fnp-3804	268	14	w	w	PROPN
fnp-3804	268	15	,	,	PUNCT
fnp-3804	268	16	geraghty	geraghty	PROPN
fnp-3804	268	17	ac	ac	PROPN
fnp-3804	268	18	,	,	PUNCT
fnp-3804	268	19	et	et	PROPN
fnp-3804	268	20	al	al	PROPN
fnp-3804	268	21	:	:	PUNCT
fnp-3804	268	22	electrical	electrical	ADJ
fnp-3804	268	23	and	and	CCONJ
fnp-3804	268	24	synaptic	synaptic	ADJ
fnp-3804	268	25	integration	integration	NOUN
fnp-3804	268	26	of	of	ADP
fnp-3804	268	27	glioma	glioma	NOUN
fnp-3804	268	28	into	into	ADP
fnp-3804	268	29	neural	neural	ADJ
fnp-3804	268	30	circuits	circuit	NOUN
fnp-3804	268	31	.	.	PUNCT
fnp-3804	269	1	nature	nature	NOUN
fnp-3804	269	2	573:539	573:539	PROPN
fnp-3804	269	3	-	-	PUNCT
fnp-3804	269	4	545	545	NUM
fnp-3804	269	5	,	,	PUNCT
fnp-3804	269	6	2019	2019	NUM
fnp-3804	269	7	venkataramani	venkataramani	NOUN
fnp-3804	269	8	v	v	NOUN
fnp-3804	269	9	,	,	PUNCT
fnp-3804	269	10	tanev	tanev	NOUN
fnp-3804	269	11	di	di	NOUN
fnp-3804	269	12	,	,	PUNCT
fnp-3804	269	13	strahle	strahle	NOUN
fnp-3804	269	14	c	c	NOUN
fnp-3804	269	15	,	,	PUNCT
fnp-3804	269	16	et	et	PROPN
fnp-3804	269	17	al	al	PROPN
fnp-3804	269	18	:	:	PUNCT
fnp-3804	269	19	glutamatergic	glutamatergic	ADJ
fnp-3804	269	20	synaptic	synaptic	ADJ
fnp-3804	269	21	input	input	NOUN
fnp-3804	269	22	to	to	ADP
fnp-3804	269	23	glioma	glioma	NOUN
fnp-3804	269	24	cells	cell	NOUN
fnp-3804	269	25	drives	drive	VERB
fnp-3804	269	26	brain	brain	VERB
fnp-3804	269	27	tumour	tumour	NOUN
fnp-3804	269	28	progression	progression	NOUN
fnp-3804	269	29	.	.	PUNCT
fnp-3804	270	1	nature	nature	NOUN
fnp-3804	271	1	573:532	573:532	PROPN
fnp-3804	271	2	-	-	SYM
fnp-3804	271	3	538	538	NUM
fnp-3804	271	4	,	,	PUNCT
fnp-3804	271	5	2019	2019	NUM
fnp-3804	271	6	monje	monje	PROPN
fnp-3804	271	7	m	m	PROPN
fnp-3804	271	8	,	,	PUNCT
fnp-3804	271	9	borniger	borniger	PROPN
fnp-3804	271	10	jc	jc	PROPN
fnp-3804	271	11	,	,	PUNCT
fnp-3804	271	12	d'silva	d'silva	PROPN
fnp-3804	271	13	nj	nj	PROPN
fnp-3804	271	14	,	,	PUNCT
fnp-3804	271	15	et	et	PROPN
fnp-3804	271	16	al	al	PROPN
fnp-3804	271	17	:	:	PUNCT
fnp-3804	271	18	roadmap	roadmap	NOUN
fnp-3804	271	19	for	for	ADP
fnp-3804	271	20	the	the	DET
fnp-3804	271	21	emerging	emerge	VERB
fnp-3804	271	22	field	field	NOUN
fnp-3804	271	23	of	of	ADP
fnp-3804	271	24	cancer	cancer	NOUN
fnp-3804	271	25	neuroscience	neuroscience	NOUN
fnp-3804	271	26	.	.	PUNCT
fnp-3804	272	1	cell	cell	NOUN
fnp-3804	272	2	181:219	181:219	NOUN
fnp-3804	272	3	-	-	PUNCT
fnp-3804	272	4	222	222	NUM
fnp-3804	272	5	,	,	PUNCT
fnp-3804	272	6	2020	2020	NUM
fnp-3804	272	7	venkatesh	venkatesh	PROPN
fnp-3804	272	8	hs	hs	PROPN
fnp-3804	272	9	,	,	PUNCT
fnp-3804	272	10	johung	johung	PROPN
fnp-3804	272	11	tb	tb	NOUN
fnp-3804	272	12	,	,	PUNCT
fnp-3804	272	13	caretti	caretti	ADJ
fnp-3804	272	14	v	v	NOUN
fnp-3804	272	15	,	,	PUNCT
fnp-3804	272	16	et	et	PROPN
fnp-3804	272	17	al	al	PROPN
fnp-3804	272	18	:	:	PUNCT
fnp-3804	272	19	neuronal	neuronal	ADJ
fnp-3804	272	20	activity	activity	NOUN
fnp-3804	272	21	promotes	promote	VERB
fnp-3804	272	22	glioma	glioma	ADJ
fnp-3804	272	23	growth	growth	NOUN
fnp-3804	272	24	through	through	ADP
fnp-3804	272	25	neuroligin-3	neuroligin-3	PRON
fnp-3804	272	26	secretion	secretion	NOUN
fnp-3804	272	27	.	.	PUNCT
fnp-3804	273	1	cell	cell	NOUN
fnp-3804	273	2	161:803	161:803	PROPN
fnp-3804	273	3	-	-	PUNCT
fnp-3804	273	4	16	16	NUM
fnp-3804	273	5	,	,	PUNCT
fnp-3804	273	6	2015	2015	NUM
fnp-3804	273	7	venkatesh	venkatesh	PROPN
fnp-3804	273	8	hs	hs	PROPN
fnp-3804	273	9	,	,	PUNCT
fnp-3804	273	10	tam	tam	PROPN
fnp-3804	273	11	lt	lt	PROPN
fnp-3804	273	12	,	,	PUNCT
fnp-3804	273	13	woo	woo	PROPN
fnp-3804	273	14	pj	pj	PROPN
fnp-3804	273	15	,	,	PUNCT
fnp-3804	273	16	et	et	PROPN
fnp-3804	273	17	al	al	PROPN
fnp-3804	273	18	:	:	PUNCT
fnp-3804	273	19	targeting	target	VERB
fnp-3804	273	20	neuronal	neuronal	ADJ
fnp-3804	273	21	activity	activity	NOUN
fnp-3804	273	22	-	-	PUNCT
fnp-3804	273	23	regulated	regulate	VERB
fnp-3804	273	24	neuroligin-3	neuroligin-3	PRON
fnp-3804	273	25	dependency	dependency	NOUN
fnp-3804	273	26	in	in	ADP
fnp-3804	273	27	high	high	ADJ
fnp-3804	273	28	-	-	PUNCT
fnp-3804	273	29	grade	grade	NOUN
fnp-3804	273	30	glioma	glioma	NOUN
fnp-3804	273	31	.	.	PUNCT
fnp-3804	274	1	nature	nature	NOUN
fnp-3804	274	2	549:533	549:533	NOUN
fnp-3804	274	3	-	-	PUNCT
fnp-3804	274	4	537	537	NUM
fnp-3804	274	5	,	,	PUNCT
fnp-3804	274	6	2017	2017	NUM
fnp-3804	274	7	filbin	filbin	VERB
fnp-3804	274	8	mg	mg	PROPN
fnp-3804	274	9	,	,	PUNCT
fnp-3804	274	10	tirosh	tirosh	VERB
fnp-3804	274	11	i	i	PRON
fnp-3804	274	12	,	,	PUNCT
fnp-3804	274	13	hovestadt	hovestadt	ADJ
fnp-3804	274	14	v	v	NOUN
fnp-3804	274	15	,	,	PUNCT
fnp-3804	274	16	et	et	PROPN
fnp-3804	274	17	al	al	PROPN
fnp-3804	274	18	:	:	PUNCT
fnp-3804	274	19	developmental	developmental	ADJ
fnp-3804	274	20	and	and	CCONJ
fnp-3804	274	21	oncogenic	oncogenic	ADJ
fnp-3804	274	22	programs	program	NOUN
fnp-3804	274	23	in	in	ADP
fnp-3804	274	24	h3k27	h3k27	PROPN
fnp-3804	274	25	m	m	NOUN
fnp-3804	274	26	gliomas	glioma	NOUN
fnp-3804	274	27	dissected	dissect	VERB
fnp-3804	274	28	by	by	ADP
fnp-3804	274	29	single	single	ADJ
fnp-3804	274	30	-	-	PUNCT
fnp-3804	274	31	cell	cell	NOUN
fnp-3804	274	32	rna	rna	NOUN
fnp-3804	274	33	-	-	PUNCT
fnp-3804	274	34	seq	seq	NOUN
fnp-3804	274	35	.	.	PUNCT
fnp-3804	275	1	science	science	NOUN
fnp-3804	275	2	360:331	360:331	NUM
fnp-3804	275	3	-	-	PUNCT
fnp-3804	275	4	335	335	NUM
fnp-3804	275	5	,	,	PUNCT
fnp-3804	275	6	2018	2018	NUM
fnp-3804	275	7	tirosh	tirosh	NOUN
fnp-3804	276	1	i	i	PRON
fnp-3804	276	2	,	,	PUNCT
fnp-3804	276	3	venteicher	venteicher	NOUN
fnp-3804	276	4	as	as	ADP
fnp-3804	276	5	,	,	PUNCT
fnp-3804	276	6	hebert	hebert	NOUN
fnp-3804	276	7	c	c	NOUN
fnp-3804	276	8	,	,	PUNCT
fnp-3804	276	9	et	et	PROPN
fnp-3804	276	10	al	al	PROPN
fnp-3804	276	11	:	:	PUNCT
fnp-3804	276	12	single	single	ADJ
fnp-3804	276	13	-	-	PUNCT
fnp-3804	276	14	cell	cell	NOUN
fnp-3804	276	15	rna	rna	NOUN
fnp-3804	276	16	-	-	PUNCT
fnp-3804	276	17	seq	seq	NOUN
fnp-3804	276	18	supports	support	VERB
fnp-3804	276	19	a	a	DET
fnp-3804	276	20	developmental	developmental	ADJ
fnp-3804	276	21	hierarchy	hierarchy	NOUN
fnp-3804	276	22	in	in	ADP
fnp-3804	276	23	human	human	ADJ
fnp-3804	276	24	oligodendroglioma	oligodendroglioma	NOUN
fnp-3804	276	25	.	.	PUNCT
fnp-3804	277	1	nature	nature	NOUN
fnp-3804	277	2	539:309	539:309	NUM
fnp-3804	277	3	-	-	SYM
fnp-3804	277	4	313	313	NUM
fnp-3804	277	5	,	,	PUNCT
fnp-3804	277	6	2016	2016	NUM
fnp-3804	277	7	venteicher	venteicher	NOUN
fnp-3804	277	8	as	as	ADP
fnp-3804	277	9	,	,	PUNCT
fnp-3804	277	10	tirosh	tirosh	NOUN
fnp-3804	277	11	i	i	PRON
fnp-3804	277	12	,	,	PUNCT
fnp-3804	277	13	hebert	hebert	PROPN
fnp-3804	277	14	c	c	PROPN
fnp-3804	277	15	,	,	PUNCT
fnp-3804	277	16	et	et	PROPN
fnp-3804	277	17	al	al	PROPN
fnp-3804	277	18	:	:	PUNCT
fnp-3804	277	19	decoupling	decouple	VERB
fnp-3804	277	20	genetics	genetic	NOUN
fnp-3804	277	21	,	,	PUNCT
fnp-3804	277	22	lineages	lineage	NOUN
fnp-3804	277	23	,	,	PUNCT
fnp-3804	277	24	and	and	CCONJ
fnp-3804	277	25	microenvironment	microenvironment	NOUN
fnp-3804	277	26	in	in	ADP
fnp-3804	277	27	idh	idh	NOUN
fnp-3804	277	28	-	-	PUNCT
fnp-3804	277	29	mutant	mutant	NOUN
fnp-3804	277	30	gliomas	glioma	NOUN
fnp-3804	277	31	by	by	ADP
fnp-3804	277	32	single	single	ADJ
fnp-3804	277	33	-	-	PUNCT
fnp-3804	277	34	cell	cell	NOUN
fnp-3804	277	35	rna	rna	NOUN
fnp-3804	277	36	-	-	PUNCT
fnp-3804	277	37	seq	seq	NOUN
fnp-3804	277	38	.	.	PUNCT
fnp-3804	278	1	science	science	NOUN
fnp-3804	278	2	355	355	NUM
fnp-3804	278	3	,	,	PUNCT
fnp-3804	278	4	2017	2017	NUM
fnp-3804	278	5	neftel	neftel	NOUN
fnp-3804	278	6	c	c	NOUN
fnp-3804	278	7	,	,	PUNCT
fnp-3804	278	8	laffy	laffy	PROPN
fnp-3804	278	9	j	j	PROPN
fnp-3804	278	10	,	,	PUNCT
fnp-3804	278	11	filbin	filbin	VERB
fnp-3804	278	12	mg	mg	PROPN
fnp-3804	278	13	,	,	PUNCT
fnp-3804	278	14	et	et	PROPN
fnp-3804	278	15	al	al	PROPN
fnp-3804	278	16	:	:	PUNCT
fnp-3804	278	17	an	an	DET
fnp-3804	278	18	integrative	integrative	ADJ
fnp-3804	278	19	model	model	NOUN
fnp-3804	278	20	of	of	ADP
fnp-3804	278	21	cellular	cellular	ADJ
fnp-3804	278	22	states	state	NOUN
fnp-3804	278	23	,	,	PUNCT
fnp-3804	278	24	plasticity	plasticity	NOUN
fnp-3804	278	25	,	,	PUNCT
fnp-3804	278	26	and	and	CCONJ
fnp-3804	278	27	genetics	genetic	NOUN
fnp-3804	278	28	for	for	ADP
fnp-3804	278	29	glioblastoma	glioblastoma	NOUN
fnp-3804	278	30	.	.	PUNCT
fnp-3804	279	1	cell	cell	NOUN
fnp-3804	279	2	178:835	178:835	NOUN
fnp-3804	279	3	-	-	PUNCT
fnp-3804	279	4	849	849	NUM
fnp-3804	279	5	e21	e21	PROPN
fnp-3804	279	6	,	,	PUNCT
fnp-3804	279	7	2019	2019	NUM
fnp-3804	279	8	brennan	brennan	PROPN
fnp-3804	279	9	cw	cw	PROPN
fnp-3804	279	10	,	,	PUNCT
fnp-3804	279	11	verhaak	verhaak	PROPN
fnp-3804	279	12	rg	rg	PROPN
fnp-3804	279	13	,	,	PUNCT
fnp-3804	279	14	mckenna	mckenna	PROPN
fnp-3804	279	15	a	a	PROPN
fnp-3804	279	16	,	,	PUNCT
fnp-3804	279	17	et	et	PROPN
fnp-3804	279	18	al	al	PROPN
fnp-3804	279	19	:	:	PUNCT
fnp-3804	279	20	the	the	DET
fnp-3804	279	21	somatic	somatic	ADJ
fnp-3804	279	22	genomic	genomic	ADJ
fnp-3804	279	23	landscape	landscape	NOUN
fnp-3804	279	24	of	of	ADP
fnp-3804	279	25	glioblastoma	glioblastoma	NOUN
fnp-3804	279	26	.	.	PUNCT
fnp-3804	280	1	cell	cell	NOUN
fnp-3804	280	2	155:462	155:462	PROPN
fnp-3804	280	3	-	-	PUNCT
fnp-3804	280	4	477	477	NUM
fnp-3804	280	5	,	,	PUNCT
fnp-3804	280	6	2013	2013	NUM
fnp-3804	280	7	bi	bi	PROPN
fnp-3804	280	8	j	j	PROPN
fnp-3804	280	9	,	,	PUNCT
fnp-3804	280	10	ichu	ichu	PROPN
fnp-3804	280	11	ta	ta	PROPN
fnp-3804	280	12	,	,	PUNCT
fnp-3804	280	13	zanca	zanca	PROPN
fnp-3804	280	14	c	c	AUX
fnp-3804	280	15	,	,	PUNCT
fnp-3804	280	16	et	et	PROPN
fnp-3804	280	17	al	al	PROPN
fnp-3804	280	18	:	:	PUNCT
fnp-3804	280	19	oncogene	oncogene	NOUN
fnp-3804	280	20	amplification	amplification	NOUN
fnp-3804	280	21	in	in	ADP
fnp-3804	280	22	growth	growth	NOUN
fnp-3804	280	23	factor	factor	NOUN
fnp-3804	280	24	signaling	signal	VERB
fnp-3804	280	25	pathways	pathway	NOUN
fnp-3804	280	26	renders	render	VERB
fnp-3804	280	27	cancers	cancer	NOUN
fnp-3804	280	28	dependent	dependent	ADJ
fnp-3804	280	29	on	on	ADP
fnp-3804	280	30	membrane	membrane	NOUN
fnp-3804	280	31	lipid	lipid	NOUN
fnp-3804	280	32	remodeling	remodeling	NOUN
fnp-3804	280	33	.	.	PUNCT
fnp-3804	281	1	cell	cell	NOUN
fnp-3804	281	2	metab	metab	PROPN
fnp-3804	281	3	30:525	30:525	NUM
fnp-3804	281	4	-	-	PUNCT
fnp-3804	281	5	538	538	NUM
fnp-3804	281	6	e8	e8	PROPN
fnp-3804	281	7	,	,	PUNCT
fnp-3804	281	8	2019	2019	NUM
fnp-3804	281	9	lemmon	lemmon	PROPN
fnp-3804	281	10	ma	ma	PROPN
fnp-3804	281	11	,	,	PUNCT
fnp-3804	281	12	schlessinger	schlessinger	PROPN
fnp-3804	281	13	j	j	PROPN
fnp-3804	281	14	,	,	PUNCT
fnp-3804	281	15	ferguson	ferguson	PROPN
fnp-3804	281	16	km	km	PROPN
fnp-3804	281	17	:	:	PUNCT
fnp-3804	281	18	the	the	DET
fnp-3804	281	19	egfr	egfr	ADJ
fnp-3804	281	20	family	family	NOUN
fnp-3804	281	21	:	:	PUNCT
fnp-3804	281	22	not	not	PART
fnp-3804	281	23	so	so	ADV
fnp-3804	281	24	prototypical	prototypical	ADJ
fnp-3804	281	25	receptor	receptor	NOUN
fnp-3804	281	26	tyrosine	tyrosine	NOUN
fnp-3804	281	27	kinases	kinase	NOUN
fnp-3804	281	28	.	.	PUNCT
fnp-3804	282	1	cold	cold	ADJ
fnp-3804	282	2	spring	spring	NOUN
fnp-3804	282	3	harb	harb	PROPN
fnp-3804	282	4	perspect	perspect	VERB
fnp-3804	282	5	biol	biol	PROPN
fnp-3804	282	6	6	6	NUM
fnp-3804	282	7	:	:	PUNCT
fnp-3804	282	8	a020768	a020768	NOUN
fnp-3804	282	9	,	,	PUNCT
fnp-3804	282	10	2014	2014	NUM
fnp-3804	282	11	nathanson	nathanson	PROPN
fnp-3804	282	12	da	da	PROPN
fnp-3804	282	13	,	,	PUNCT
fnp-3804	282	14	gini	gini	PROPN
fnp-3804	282	15	b	b	PROPN
fnp-3804	282	16	,	,	PUNCT
fnp-3804	282	17	mottahedeh	mottahedeh	PROPN
fnp-3804	282	18	j	j	PROPN
fnp-3804	282	19	,	,	PUNCT
fnp-3804	282	20	et	et	PROPN
fnp-3804	282	21	al	al	PROPN
fnp-3804	282	22	:	:	PUNCT
fnp-3804	282	23	targeted	target	VERB
fnp-3804	282	24	therapy	therapy	NOUN
fnp-3804	282	25	resistance	resistance	NOUN
fnp-3804	282	26	mediated	mediate	VERB
fnp-3804	282	27	by	by	ADP
fnp-3804	282	28	dynamic	dynamic	ADJ
fnp-3804	282	29	regulation	regulation	NOUN
fnp-3804	282	30	of	of	ADP
fnp-3804	282	31	extrachromosomal	extrachromosomal	ADJ
fnp-3804	282	32	mutant	mutant	NOUN
fnp-3804	282	33	egfr	egfr	PROPN
fnp-3804	282	34	dna	dna	PROPN
fnp-3804	282	35	.	.	PUNCT
fnp-3804	283	1	science	science	PROPN
fnp-3804	283	2	343:72	343:72	PROPN
fnp-3804	283	3	-	-	SYM
fnp-3804	283	4	76	76	NUM
fnp-3804	283	5	,	,	PUNCT
fnp-3804	283	6	2014	2014	NUM
fnp-3804	283	7	hill	hill	PROPN
fnp-3804	283	8	rm	rm	PROPN
fnp-3804	283	9	,	,	PUNCT
fnp-3804	283	10	plasschaert	plasschaert	PROPN
fnp-3804	283	11	sla	sla	PROPN
fnp-3804	283	12	,	,	PUNCT
fnp-3804	283	13	timmermann	timmermann	VERB
fnp-3804	283	14	b	b	X
fnp-3804	283	15	,	,	PUNCT
fnp-3804	283	16	et	et	PROPN
fnp-3804	283	17	al	al	PROPN
fnp-3804	283	18	:	:	PUNCT
fnp-3804	283	19	relapsed	relapse	VERB
fnp-3804	283	20	medulloblastoma	medulloblastoma	NOUN
fnp-3804	283	21	in	in	ADP
fnp-3804	283	22	pre	pre	ADJ
fnp-3804	283	23	-	-	ADJ
fnp-3804	283	24	irradiated	irradiated	ADJ
fnp-3804	283	25	patients	patient	NOUN
fnp-3804	283	26	:	:	PUNCT
fnp-3804	283	27	current	current	ADJ
fnp-3804	283	28	practice	practice	NOUN
fnp-3804	283	29	for	for	ADP
fnp-3804	283	30	diagnostics	diagnostic	NOUN
fnp-3804	283	31	and	and	CCONJ
fnp-3804	283	32	treatment	treatment	NOUN
fnp-3804	283	33	.	.	PUNCT
fnp-3804	284	1	cancers	cancer	NOUN
fnp-3804	284	2	(	(	PUNCT
fnp-3804	284	3	basel	basel	PROPN
fnp-3804	284	4	)	)	PUNCT
fnp-3804	284	5	14	14	NUM
fnp-3804	284	6	,	,	PUNCT
fnp-3804	284	7	2021	2021	NUM
fnp-3804	284	8	escudero	escudero	PROPN
fnp-3804	284	9	l	l	PROPN
fnp-3804	284	10	,	,	PUNCT
fnp-3804	284	11	llort	llort	NOUN
fnp-3804	284	12	a	a	NOUN
fnp-3804	284	13	,	,	PUNCT
fnp-3804	284	14	arias	arias	PROPN
fnp-3804	284	15	a	a	PRON
fnp-3804	284	16	,	,	PUNCT
fnp-3804	284	17	et	et	PROPN
fnp-3804	284	18	al	al	PROPN
fnp-3804	284	19	:	:	PUNCT
fnp-3804	284	20	circulating	circulate	VERB
fnp-3804	284	21	tumour	tumour	NOUN
fnp-3804	284	22	dna	dna	NOUN
fnp-3804	284	23	from	from	ADP
fnp-3804	284	24	the	the	DET
fnp-3804	284	25	cerebrospinal	cerebrospinal	ADJ
fnp-3804	284	26	fluid	fluid	NOUN
fnp-3804	284	27	allows	allow	VERB
fnp-3804	284	28	the	the	DET
fnp-3804	284	29	characterisation	characterisation	NOUN
fnp-3804	284	30	and	and	CCONJ
fnp-3804	284	31	monitoring	monitoring	NOUN
fnp-3804	284	32	of	of	ADP
fnp-3804	284	33	medulloblastoma	medulloblastoma	NOUN
fnp-3804	284	34	.	.	PUNCT
fnp-3804	285	1	nat	nat	PROPN
fnp-3804	285	2	commun	commun	PROPN
fnp-3804	285	3	11:5376	11:5376	PROPN
fnp-3804	285	4	,	,	PUNCT
fnp-3804	285	5	2020	2020	NUM
fnp-3804	285	6	goldbrunner	goldbrunner	NOUN
fnp-3804	285	7	r	r	NOUN
fnp-3804	285	8	,	,	PUNCT
fnp-3804	285	9	stavrinou	stavrinou	NOUN
fnp-3804	285	10	p	p	NOUN
fnp-3804	285	11	,	,	PUNCT
fnp-3804	285	12	jenkinson	jenkinson	PROPN
fnp-3804	285	13	md	md	PROPN
fnp-3804	285	14	,	,	PUNCT
fnp-3804	285	15	et	et	PROPN
fnp-3804	285	16	al	al	PROPN
fnp-3804	285	17	:	:	PUNCT
fnp-3804	285	18	eano	eano	PROPN
fnp-3804	285	19	guideline	guideline	NOUN
fnp-3804	285	20	on	on	ADP
fnp-3804	285	21	the	the	DET
fnp-3804	285	22	diagnosis	diagnosis	NOUN
fnp-3804	285	23	and	and	CCONJ
fnp-3804	285	24	management	management	NOUN
fnp-3804	285	25	of	of	ADP
fnp-3804	285	26	meningiomas	meningiomas	PROPN
fnp-3804	285	27	.	.	PUNCT
fnp-3804	286	1	neuro	neuro	PROPN
fnp-3804	286	2	oncol	oncol	ADJ
fnp-3804	286	3	23:1821	23:1821	NUM
fnp-3804	286	4	-	-	SYM
fnp-3804	286	5	1834	1834	NUM
fnp-3804	286	6	,	,	PUNCT
fnp-3804	286	7	2021	2021	NUM
fnp-3804	286	8	louis	louis	PROPN
fnp-3804	286	9	dn	dn	PROPN
fnp-3804	286	10	,	,	PUNCT
fnp-3804	286	11	wesseling	wessele	VERB
fnp-3804	286	12	p	p	PRON
fnp-3804	286	13	,	,	PUNCT
fnp-3804	286	14	paulus	paulus	PROPN
fnp-3804	286	15	w	w	PROPN
fnp-3804	286	16	,	,	PUNCT
fnp-3804	286	17	et	et	PROPN
fnp-3804	286	18	al	al	PROPN
fnp-3804	286	19	:	:	PUNCT
fnp-3804	286	20	cimpact	cimpact	ADJ
fnp-3804	286	21	-	-	PUNCT
fnp-3804	286	22	now	now	ADV
fnp-3804	286	23	update	update	NOUN
fnp-3804	286	24	1	1	NUM
fnp-3804	286	25	:	:	PUNCT
fnp-3804	286	26	not	not	PART
fnp-3804	286	27	otherwise	otherwise	ADV
fnp-3804	286	28	specified	specify	VERB
fnp-3804	286	29	(	(	PUNCT
fnp-3804	286	30	nos	nos	NOUN
fnp-3804	286	31	)	)	PUNCT
fnp-3804	286	32	and	and	CCONJ
fnp-3804	286	33	not	not	PART
fnp-3804	286	34	elsewhere	elsewhere	ADV
fnp-3804	286	35	classified	classified	ADJ
fnp-3804	286	36	(	(	PUNCT
fnp-3804	286	37	nec	nec	PROPN
fnp-3804	286	38	)	)	PUNCT
fnp-3804	286	39	.	.	PUNCT
fnp-3804	287	1	acta	acta	PROPN
fnp-3804	287	2	neuropathol	neuropathol	PROPN
fnp-3804	287	3	135:481	135:481	PROPN
fnp-3804	287	4	-	-	PUNCT
fnp-3804	287	5	484	484	NUM
fnp-3804	287	6	,	,	PUNCT
fnp-3804	287	7	2018	2018	NUM
fnp-3804	287	8	behling	behle	VERB
fnp-3804	287	9	f	f	PROPN
fnp-3804	287	10	,	,	PUNCT
fnp-3804	287	11	fodi	fodi	VERB
fnp-3804	287	12	c	c	NOUN
fnp-3804	287	13	,	,	PUNCT
fnp-3804	287	14	gepfner	gepfner	NOUN
fnp-3804	287	15	-	-	PUNCT
fnp-3804	287	16	tuma	tuma	NOUN
fnp-3804	287	17	i	i	PROPN
fnp-3804	287	18	,	,	PUNCT
fnp-3804	287	19	et	et	PROPN
fnp-3804	287	20	al	al	PROPN
fnp-3804	287	21	:	:	PUNCT
fnp-3804	288	1	h3k27me3	h3k27me3	PROPN
fnp-3804	288	2	loss	loss	NOUN
fnp-3804	288	3	indicates	indicate	VERB
fnp-3804	288	4	an	an	DET
fnp-3804	288	5	increased	increased	ADJ
fnp-3804	288	6	risk	risk	NOUN
fnp-3804	288	7	of	of	ADP
fnp-3804	288	8	recurrence	recurrence	NOUN
fnp-3804	288	9	in	in	ADP
fnp-3804	288	10	the	the	DET
fnp-3804	288	11	tubingen	tubingen	NOUN
fnp-3804	288	12	meningioma	meningioma	NOUN
fnp-3804	288	13	cohort	cohort	NOUN
fnp-3804	288	14	.	.	PUNCT
fnp-3804	289	1	neuro	neuro	PROPN
fnp-3804	289	2	oncol	oncol	ADJ
fnp-3804	289	3	23:1273	23:1273	NOUN
fnp-3804	289	4	-	-	PUNCT
fnp-3804	289	5	1281	1281	NUM
fnp-3804	289	6	,	,	PUNCT
fnp-3804	289	7	2021	2021	NUM
fnp-3804	289	8	nassiri	nassiri	NOUN
fnp-3804	289	9	f	f	PROPN
fnp-3804	289	10	,	,	PUNCT
fnp-3804	289	11	wang	wang	PROPN
fnp-3804	289	12	jz	jz	PROPN
fnp-3804	289	13	,	,	PUNCT
fnp-3804	289	14	singh	singh	PROPN
fnp-3804	289	15	o	o	NOUN
fnp-3804	289	16	,	,	PUNCT
fnp-3804	289	17	et	et	PROPN
fnp-3804	289	18	al	al	PROPN
fnp-3804	289	19	:	:	PUNCT
fnp-3804	289	20	loss	loss	NOUN
fnp-3804	289	21	of	of	ADP
fnp-3804	289	22	h3k27me3	h3k27me3	PROPN
fnp-3804	289	23	in	in	ADP
fnp-3804	289	24	meningiomas	meningiomas	PROPN
fnp-3804	289	25	.	.	PUNCT
fnp-3804	290	1	neuro	neuro	PROPN
fnp-3804	290	2	oncol	oncol	PROPN
fnp-3804	290	3	23:1282	23:1282	PROPN
fnp-3804	290	4	-	-	PUNCT
fnp-3804	290	5	1291	1291	NUM
fnp-3804	290	6	,	,	PUNCT
fnp-3804	290	7	2021	2021	NUM
fnp-3804	290	8	kirches	kirche	NOUN
fnp-3804	290	9	e	e	NOUN
fnp-3804	290	10	,	,	PUNCT
fnp-3804	290	11	sahm	sahm	PROPN
fnp-3804	290	12	f	f	PROPN
fnp-3804	290	13	,	,	PUNCT
fnp-3804	290	14	korshunov	korshunov	PROPN
fnp-3804	290	15	a	a	X
fnp-3804	290	16	,	,	PUNCT
fnp-3804	290	17	et	et	PROPN
fnp-3804	290	18	al	al	PROPN
fnp-3804	290	19	:	:	PUNCT
fnp-3804	290	20	molecular	molecular	ADJ
fnp-3804	290	21	profiling	profiling	NOUN
fnp-3804	290	22	of	of	ADP
fnp-3804	290	23	pediatric	pediatric	ADJ
fnp-3804	290	24	meningiomas	meningioma	NOUN
fnp-3804	290	25	shows	show	VERB
fnp-3804	290	26	tumor	tumor	NOUN
fnp-3804	290	27	characteristics	characteristic	NOUN
fnp-3804	290	28	distinct	distinct	ADJ
fnp-3804	290	29	from	from	ADP
fnp-3804	290	30	adult	adult	NOUN
fnp-3804	290	31	meningiomas	meningioma	NOUN
fnp-3804	290	32	.	.	PUNCT
fnp-3804	291	1	acta	acta	PROPN
fnp-3804	291	2	neuropathol	neuropathol	PROPN
fnp-3804	291	3	142:873	142:873	PROPN
fnp-3804	291	4	-	-	PUNCT
fnp-3804	291	5	886	886	NUM
fnp-3804	291	6	,	,	PUNCT
fnp-3804	291	7	2021	2021	NUM
fnp-3804	291	8	bagaev	bagaev	PROPN
fnp-3804	291	9	a	a	X
fnp-3804	291	10	,	,	PUNCT
fnp-3804	291	11	kotlov	kotlov	PROPN
fnp-3804	291	12	n	n	CCONJ
fnp-3804	291	13	,	,	PUNCT
fnp-3804	291	14	nomie	nomie	VERB
fnp-3804	291	15	k	k	PROPN
fnp-3804	291	16	,	,	PUNCT
fnp-3804	291	17	et	et	PROPN
fnp-3804	291	18	al	al	PROPN
fnp-3804	291	19	:	:	PUNCT
fnp-3804	291	20	conserved	conserve	VERB
fnp-3804	291	21	pan	pan	ADJ
fnp-3804	291	22	-	-	ADJ
fnp-3804	291	23	cancer	cancer	ADJ
fnp-3804	291	24	microenvironment	microenvironment	ADJ
fnp-3804	291	25	subtypes	subtype	NOUN
fnp-3804	291	26	predict	predict	VERB
fnp-3804	291	27	response	response	NOUN
fnp-3804	291	28	to	to	ADP
fnp-3804	291	29	immunotherapy	immunotherapy	NOUN
fnp-3804	291	30	.	.	PUNCT
fnp-3804	292	1	cancer	cancer	NOUN
fnp-3804	292	2	cell	cell	NOUN
fnp-3804	292	3	39:845	39:845	NUM
fnp-3804	292	4	-	-	SYM
fnp-3804	292	5	865	865	NUM
fnp-3804	292	6	e7	e7	PROPN
fnp-3804	292	7	,	,	PUNCT
fnp-3804	292	8	2021	2021	NUM
fnp-3804	292	9	jin	jin	NOUN
fnp-3804	292	10	x	x	NOUN
fnp-3804	292	11	,	,	PUNCT
fnp-3804	292	12	demere	demere	ADV
fnp-3804	292	13	z	z	PROPN
fnp-3804	292	14	,	,	PUNCT
fnp-3804	292	15	nair	nair	PROPN
fnp-3804	292	16	k	k	PROPN
fnp-3804	292	17	,	,	PUNCT
fnp-3804	292	18	et	et	PROPN
fnp-3804	292	19	al	al	PROPN
fnp-3804	292	20	:	:	PUNCT
fnp-3804	292	21	a	a	DET
fnp-3804	292	22	metastasis	metastasis	NOUN
fnp-3804	292	23	map	map	NOUN
fnp-3804	292	24	of	of	ADP
fnp-3804	292	25	human	human	ADJ
fnp-3804	292	26	cancer	cancer	NOUN
fnp-3804	292	27	cell	cell	NOUN
fnp-3804	292	28	lines	line	NOUN
fnp-3804	292	29	.	.	PUNCT
fnp-3804	293	1	nature	nature	NOUN
fnp-3804	294	1	588:331	588:331	NUM
fnp-3804	294	2	-	-	PUNCT
fnp-3804	294	3	336	336	NUM
fnp-3804	294	4	,	,	PUNCT
fnp-3804	294	5	2020	2020	NUM
fnp-3804	294	6	pages	page	NOUN
fnp-3804	294	7	m	m	PROPN
fnp-3804	294	8	,	,	PUNCT
fnp-3804	294	9	rotem	rotem	PROPN
fnp-3804	294	10	d	d	PROPN
fnp-3804	294	11	,	,	PUNCT
fnp-3804	294	12	gydush	gydush	VERB
fnp-3804	294	13	g	g	PROPN
fnp-3804	294	14	,	,	PUNCT
fnp-3804	294	15	et	et	PROPN
fnp-3804	294	16	al	al	PROPN
fnp-3804	294	17	:	:	PUNCT
fnp-3804	294	18	liquid	liquid	ADJ
fnp-3804	294	19	biopsy	biopsy	NOUN
fnp-3804	294	20	detection	detection	NOUN
fnp-3804	294	21	of	of	ADP
fnp-3804	294	22	genomic	genomic	ADJ
fnp-3804	294	23	alterations	alteration	NOUN
fnp-3804	294	24	in	in	ADP
fnp-3804	294	25	pediatric	pediatric	ADJ
fnp-3804	294	26	brain	brain	NOUN
fnp-3804	294	27	tumors	tumor	NOUN
fnp-3804	294	28	from	from	ADP
fnp-3804	294	29	cell	cell	NOUN
fnp-3804	294	30	-	-	PUNCT
fnp-3804	294	31	free	free	ADJ
fnp-3804	294	32	dna	dna	NOUN
fnp-3804	294	33	in	in	ADP
fnp-3804	294	34	peripheral	peripheral	ADJ
fnp-3804	294	35	blood	blood	NOUN
fnp-3804	294	36	,	,	PUNCT
fnp-3804	294	37	csf	csf	PROPN
fnp-3804	294	38	,	,	PUNCT
fnp-3804	294	39	and	and	CCONJ
fnp-3804	294	40	urine	urine	NOUN
fnp-3804	294	41	.	.	PUNCT
fnp-3804	295	1	neuro	neuro	PROPN
fnp-3804	295	2	oncol	oncol	PROPN
fnp-3804	295	3	,	,	PUNCT
fnp-3804	295	4	2022	2022	NUM
fnp-3804	295	5	sievers	siever	NOUN
fnp-3804	295	6	p	p	PRON
fnp-3804	295	7	,	,	PUNCT
fnp-3804	295	8	henneken	henneken	PROPN
fnp-3804	295	9	sc	sc	PROPN
fnp-3804	295	10	,	,	PUNCT
fnp-3804	295	11	blume	blume	PROPN
fnp-3804	295	12	c	c	PROPN
fnp-3804	295	13	,	,	PUNCT
fnp-3804	295	14	et	et	PROPN
fnp-3804	295	15	al	al	PROPN
fnp-3804	295	16	:	:	PUNCT
fnp-3804	295	17	recurrent	recurrent	ADJ
fnp-3804	295	18	fusions	fusion	NOUN
fnp-3804	295	19	in	in	ADP
fnp-3804	295	20	plagl1	plagl1	PROPN
fnp-3804	295	21	define	define	VERB
fnp-3804	295	22	a	a	DET
fnp-3804	295	23	distinct	distinct	ADJ
fnp-3804	295	24	subset	subset	NOUN
fnp-3804	295	25	of	of	ADP
fnp-3804	295	26	pediatric	pediatric	ADJ
fnp-3804	295	27	-	-	PUNCT
fnp-3804	295	28	type	type	NOUN
fnp-3804	295	29	supratentorial	supratentorial	ADJ
fnp-3804	295	30	neuroepithelial	neuroepithelial	ADJ
fnp-3804	295	31	tumors	tumor	NOUN
fnp-3804	295	32	.	.	PUNCT
fnp-3804	296	1	acta	acta	PROPN
fnp-3804	296	2	neuropathol	neuropathol	PROPN
fnp-3804	296	3	142:827	142:827	PROPN
fnp-3804	296	4	-	-	PUNCT
fnp-3804	296	5	839	839	NUM
fnp-3804	296	6	,	,	PUNCT
fnp-3804	296	7	2021	2021	NUM
fnp-3804	296	8	alhalabi	alhalabi	PROPN
fnp-3804	296	9	kt	kt	PROPN
fnp-3804	296	10	,	,	PUNCT
fnp-3804	296	11	stichel	stichel	PROPN
fnp-3804	296	12	d	d	PROPN
fnp-3804	296	13	,	,	PUNCT
fnp-3804	296	14	sievers	sievers	PROPN
fnp-3804	296	15	p	p	PROPN
fnp-3804	296	16	,	,	PUNCT
fnp-3804	296	17	et	et	PROPN
fnp-3804	296	18	al	al	PROPN
fnp-3804	296	19	:	:	PUNCT
fnp-3804	296	20	patz1	patz1	PROPN
fnp-3804	296	21	fusions	fusion	NOUN
fnp-3804	296	22	define	define	VERB
fnp-3804	296	23	a	a	DET
fnp-3804	296	24	novel	novel	NOUN
fnp-3804	296	25	molecularly	molecularly	ADV
fnp-3804	296	26	distinct	distinct	ADJ
fnp-3804	296	27	neuroepithelial	neuroepithelial	ADJ
fnp-3804	296	28	tumor	tumor	NOUN
fnp-3804	296	29	entity	entity	NOUN
fnp-3804	296	30	with	with	ADP
fnp-3804	296	31	a	a	DET
fnp-3804	296	32	broad	broad	ADJ
fnp-3804	296	33	histological	histological	ADJ
fnp-3804	296	34	spectrum	spectrum	NOUN
fnp-3804	296	35	.	.	PUNCT
fnp-3804	297	1	acta	acta	PROPN
fnp-3804	297	2	neuropathol	neuropathol	PROPN
fnp-3804	297	3	142:841	142:841	PROPN
fnp-3804	297	4	-	-	SYM
fnp-3804	297	5	857	857	NUM
fnp-3804	297	6	,	,	PUNCT
fnp-3804	297	7	2021	2021	NUM
fnp-3804	297	8	coltin	coltin	NOUN
fnp-3804	297	9	h	h	NOUN
fnp-3804	297	10	,	,	PUNCT
fnp-3804	297	11	sundaresan	sundaresan	PROPN
fnp-3804	297	12	l	l	PROPN
fnp-3804	297	13	,	,	PUNCT
fnp-3804	297	14	smith	smith	PROPN
fnp-3804	297	15	ks	ks	PROPN
fnp-3804	297	16	,	,	PUNCT
fnp-3804	297	17	et	et	PROPN
fnp-3804	297	18	al	al	PROPN
fnp-3804	297	19	:	:	PUNCT
fnp-3804	297	20	subgroup	subgroup	NOUN
fnp-3804	297	21	and	and	CCONJ
fnp-3804	297	22	subtype	subtype	NOUN
fnp-3804	297	23	-	-	PUNCT
fnp-3804	297	24	specific	specific	ADJ
fnp-3804	297	25	outcomes	outcome	NOUN
fnp-3804	297	26	in	in	ADP
fnp-3804	297	27	adult	adult	NOUN
fnp-3804	297	28	medulloblastoma	medulloblastoma	NOUN
fnp-3804	297	29	.	.	PUNCT
fnp-3804	298	1	acta	acta	PROPN
fnp-3804	298	2	neuropathol	neuropathol	PROPN
fnp-3804	298	3	142:859	142:859	PROPN
fnp-3804	298	4	-	-	PUNCT
fnp-3804	298	5	871	871	PROPN
fnp-3804	298	6	,	,	PUNCT
fnp-3804	298	7	2021	2021	NUM
fnp-3804	298	8	forster	forster	PROPN
fnp-3804	298	9	a	a	X
fnp-3804	298	10	,	,	PUNCT
fnp-3804	298	11	brand	brand	NOUN
fnp-3804	298	12	f	f	PROPN
fnp-3804	298	13	,	,	PUNCT
fnp-3804	298	14	banan	banan	NOUN
fnp-3804	298	15	r	r	NOUN
fnp-3804	298	16	,	,	PUNCT
fnp-3804	298	17	et	et	PROPN
fnp-3804	298	18	al	al	PROPN
fnp-3804	298	19	:	:	PUNCT
fnp-3804	298	20	rare	rare	ADJ
fnp-3804	298	21	germline	germline	NOUN
fnp-3804	298	22	variants	variant	NOUN
fnp-3804	298	23	in	in	ADP
fnp-3804	298	24	the	the	DET
fnp-3804	298	25	e	e	PROPN
fnp-3804	298	26	-	-	NOUN
fnp-3804	298	27	cadherin	cadherin	NOUN
fnp-3804	298	28	gene	gene	NOUN
fnp-3804	298	29	cdh1	cdh1	NOUN
fnp-3804	298	30	are	be	AUX
fnp-3804	298	31	associated	associate	VERB
fnp-3804	298	32	with	with	ADP
fnp-3804	298	33	the	the	DET
fnp-3804	298	34	risk	risk	NOUN
fnp-3804	298	35	of	of	ADP
fnp-3804	298	36	brain	brain	NOUN
fnp-3804	298	37	tumors	tumor	NOUN
fnp-3804	298	38	of	of	ADP
fnp-3804	298	39	neuroepithelial	neuroepithelial	ADJ
fnp-3804	298	40	and	and	CCONJ
fnp-3804	298	41	epithelial	epithelial	ADJ
fnp-3804	298	42	origin	origin	NOUN
fnp-3804	298	43	.	.	PUNCT
fnp-3804	299	1	acta	acta	PROPN
fnp-3804	299	2	neuropathol	neuropathol	PROPN
fnp-3804	299	3	142:191	142:191	PROPN
fnp-3804	299	4	-	-	SYM
fnp-3804	299	5	210	210	NUM
fnp-3804	299	6	,	,	PUNCT
fnp-3804	299	7	2021	2021	NUM
fnp-3804	299	8	brandner	brandner	NOUN
fnp-3804	299	9	s	s	PROPN
fnp-3804	299	10	,	,	PUNCT
fnp-3804	299	11	mcaleenan	mcaleenan	NOUN
fnp-3804	299	12	a	a	PRON
fnp-3804	299	13	,	,	PUNCT
fnp-3804	299	14	jones	jones	PROPN
fnp-3804	300	1	he	he	PRON
fnp-3804	300	2	,	,	PUNCT
fnp-3804	300	3	et	et	PROPN
fnp-3804	300	4	al	al	PROPN
fnp-3804	300	5	:	:	PUNCT
fnp-3804	300	6	diagnostic	diagnostic	ADJ
fnp-3804	300	7	accuracy	accuracy	NOUN
fnp-3804	300	8	of	of	ADP
fnp-3804	300	9	1p/19q	1p/19q	NOUN
fnp-3804	300	10	codeletion	codeletion	NOUN
fnp-3804	300	11	tests	test	NOUN
fnp-3804	300	12	in	in	ADP
fnp-3804	300	13	oligodendroglioma	oligodendroglioma	NOUN
fnp-3804	300	14	:	:	PUNCT
fnp-3804	300	15	a	a	DET
fnp-3804	300	16	comprehensive	comprehensive	ADJ
fnp-3804	300	17	meta	meta	ADJ
fnp-3804	300	18	-	-	PUNCT
fnp-3804	300	19	analysis	analysis	NOUN
fnp-3804	300	20	based	base	VERB
fnp-3804	300	21	on	on	ADP
fnp-3804	300	22	a	a	DET
fnp-3804	300	23	cochrane	cochrane	PROPN
fnp-3804	300	24	systematic	systematic	PROPN
fnp-3804	300	25	review	review	PROPN
fnp-3804	300	26	.	.	PUNCT
fnp-3804	301	1	neuropathol	neuropathol	PROPN
fnp-3804	301	2	appl	appl	PROPN
fnp-3804	301	3	neurobiol	neurobiol	PROPN
fnp-3804	301	4	,	,	PUNCT
fnp-3804	301	5	2021	2021	NUM
fnp-3804	301	6	mcaleenan	mcaleenan	NOUN
fnp-3804	301	7	a	a	PRON
fnp-3804	301	8	,	,	PUNCT
fnp-3804	301	9	kelly	kelly	PROPN
fnp-3804	301	10	c	c	PROPN
fnp-3804	301	11	,	,	PUNCT
fnp-3804	301	12	spiga	spiga	PROPN
fnp-3804	301	13	f	f	NOUN
fnp-3804	301	14	,	,	PUNCT
fnp-3804	301	15	et	et	PROPN
fnp-3804	301	16	al	al	PROPN
fnp-3804	301	17	:	:	PUNCT
fnp-3804	301	18	prognostic	prognostic	ADJ
fnp-3804	301	19	value	value	NOUN
fnp-3804	301	20	of	of	ADP
fnp-3804	301	21	test(s	test(s	PROPN
fnp-3804	301	22	)	)	PUNCT
fnp-3804	301	23	for	for	ADP
fnp-3804	301	24	o6	o6	NOUN
fnp-3804	301	25	-	-	PUNCT
fnp-3804	301	26	methylguanine	methylguanine	NOUN
fnp-3804	301	27	-	-	PUNCT
fnp-3804	301	28	dna	dna	NOUN
fnp-3804	301	29	methyltransferase	methyltransferase	NOUN
fnp-3804	301	30	(	(	PUNCT
fnp-3804	301	31	mgmt	mgmt	NOUN
fnp-3804	301	32	)	)	PUNCT
fnp-3804	301	33	promoter	promoter	NOUN
fnp-3804	301	34	methylation	methylation	NOUN
fnp-3804	301	35	for	for	ADP
fnp-3804	301	36	predicting	predict	VERB
fnp-3804	301	37	overall	overall	ADJ
fnp-3804	301	38	survival	survival	NOUN
fnp-3804	301	39	in	in	ADP
fnp-3804	301	40	people	people	NOUN
fnp-3804	301	41	with	with	ADP
fnp-3804	301	42	glioblastoma	glioblastoma	NOUN
fnp-3804	301	43	treated	treat	VERB
fnp-3804	301	44	with	with	ADP
fnp-3804	301	45	temozolomide	temozolomide	NOUN
fnp-3804	301	46	.	.	PUNCT
fnp-3804	302	1	cochrane	cochrane	PROPN
fnp-3804	302	2	database	database	PROPN
fnp-3804	302	3	syst	syst	PROPN
fnp-3804	302	4	rev	rev	VERB
fnp-3804	302	5	3	3	NUM
fnp-3804	302	6	:	:	PUNCT
fnp-3804	302	7	cd013316	cd013316	ADJ
fnp-3804	302	8	,	,	PUNCT
fnp-3804	302	9	2021	2021	NUM
fnp-3804	302	10	brandner	brandner	NOUN
fnp-3804	302	11	s	s	PROPN
fnp-3804	302	12	,	,	PUNCT
fnp-3804	302	13	mcaleenan	mcaleenan	VERB
fnp-3804	302	14	a	a	PRON
fnp-3804	302	15	,	,	PUNCT
fnp-3804	302	16	kelly	kelly	PROPN
fnp-3804	302	17	c	c	PROPN
fnp-3804	302	18	,	,	PUNCT
fnp-3804	302	19	et	et	PROPN
fnp-3804	302	20	al	al	PROPN
fnp-3804	302	21	:	:	PUNCT
fnp-3804	302	22	mgmt	mgmt	PROPN
fnp-3804	302	23	promoter	promoter	NOUN
fnp-3804	302	24	methylation	methylation	NOUN
fnp-3804	302	25	testing	testing	NOUN
fnp-3804	302	26	to	to	PART
fnp-3804	302	27	predict	predict	VERB
fnp-3804	302	28	overall	overall	ADJ
fnp-3804	302	29	survival	survival	NOUN
fnp-3804	302	30	in	in	ADP
fnp-3804	302	31	people	people	NOUN
fnp-3804	302	32	with	with	ADP
fnp-3804	302	33	glioblastoma	glioblastoma	NOUN
fnp-3804	302	34	treated	treat	VERB
fnp-3804	302	35	with	with	ADP
fnp-3804	302	36	temozolomide	temozolomide	NOUN
fnp-3804	302	37	:	:	PUNCT
fnp-3804	302	38	a	a	DET
fnp-3804	302	39	comprehensive	comprehensive	ADJ
fnp-3804	302	40	meta	meta	ADJ
fnp-3804	302	41	-	-	PUNCT
fnp-3804	302	42	analysis	analysis	NOUN
fnp-3804	302	43	based	base	VERB
fnp-3804	302	44	on	on	ADP
fnp-3804	302	45	a	a	DET
fnp-3804	302	46	cochrane	cochrane	PROPN
fnp-3804	302	47	systematic	systematic	PROPN
fnp-3804	302	48	review	review	PROPN
fnp-3804	302	49	.	.	PUNCT
fnp-3804	303	1	neuro	neuro	PROPN
fnp-3804	303	2	oncol	oncol	ADJ
fnp-3804	303	3	23:1457	23:1457	NOUN
fnp-3804	303	4	-	-	SYM
fnp-3804	303	5	1469	1469	NUM
fnp-3804	303	6	,	,	PUNCT
fnp-3804	303	7	2021	2021	NUM
fnp-3804	303	8	carlson	carlson	PROPN
fnp-3804	303	9	jc	jc	PROPN
fnp-3804	303	10	,	,	PUNCT
fnp-3804	303	11	cantu	cantu	VERB
fnp-3804	303	12	gutierrez	gutierrez	PROPN
fnp-3804	303	13	m	m	PROPN
fnp-3804	303	14	,	,	PUNCT
fnp-3804	303	15	lozzi	lozzi	PROPN
fnp-3804	303	16	b	b	PROPN
fnp-3804	303	17	,	,	PUNCT
fnp-3804	303	18	et	et	PROPN
fnp-3804	303	19	al	al	PROPN
fnp-3804	303	20	:	:	PUNCT
fnp-3804	303	21	identification	identification	NOUN
fnp-3804	303	22	of	of	ADP
fnp-3804	303	23	diverse	diverse	ADJ
fnp-3804	303	24	tumor	tumor	NOUN
fnp-3804	303	25	endothelial	endothelial	NOUN
fnp-3804	303	26	cell	cell	NOUN
fnp-3804	303	27	populations	population	NOUN
fnp-3804	303	28	in	in	ADP
fnp-3804	303	29	malignant	malignant	ADJ
fnp-3804	303	30	glioma	glioma	NOUN
fnp-3804	303	31	.	.	PUNCT
fnp-3804	304	1	neuro	neuro	PROPN
fnp-3804	304	2	oncol	oncol	ADJ
fnp-3804	304	3	23:932	23:932	NUM
fnp-3804	304	4	-	-	SYM
fnp-3804	304	5	944	944	NUM
fnp-3804	304	6	,	,	PUNCT
fnp-3804	304	7	2021	2021	NUM
fnp-3804	304	8	rustenhoven	rustenhoven	PROPN
fnp-3804	304	9	j	j	PROPN
fnp-3804	304	10	,	,	PUNCT
fnp-3804	304	11	drieu	drieu	PROPN
fnp-3804	304	12	a	a	PRON
fnp-3804	304	13	,	,	PUNCT
fnp-3804	304	14	mamuladze	mamuladze	PROPN
fnp-3804	304	15	t	t	PROPN
fnp-3804	304	16	,	,	PUNCT
fnp-3804	304	17	et	et	PROPN
fnp-3804	304	18	al	al	PROPN
fnp-3804	304	19	:	:	PUNCT
fnp-3804	304	20	functional	functional	ADJ
fnp-3804	304	21	characterization	characterization	NOUN
fnp-3804	304	22	of	of	ADP
fnp-3804	304	23	the	the	DET
fnp-3804	304	24	dural	dural	ADJ
fnp-3804	304	25	sinuses	sinus	NOUN
fnp-3804	304	26	as	as	ADP
fnp-3804	304	27	a	a	DET
fnp-3804	304	28	neuroimmune	neuroimmune	NOUN
fnp-3804	304	29	interface	interface	NOUN
fnp-3804	304	30	.	.	PUNCT
fnp-3804	305	1	cell	cell	NOUN
fnp-3804	305	2	184:1000	184:1000	NUM
fnp-3804	305	3	-	-	SYM
fnp-3804	305	4	1016	1016	NUM
fnp-3804	305	5	e27	e27	NOUN
fnp-3804	305	6	,	,	PUNCT
fnp-3804	305	7	2021	2021	NUM
fnp-3804	305	8	cugurra	cugurra	VERB
fnp-3804	305	9	a	a	PRON
fnp-3804	305	10	,	,	PUNCT
fnp-3804	305	11	mamuladze	mamuladze	PROPN
fnp-3804	305	12	t	t	PROPN
fnp-3804	305	13	,	,	PUNCT
fnp-3804	305	14	rustenhoven	rustenhoven	PROPN
fnp-3804	305	15	j	j	PROPN
fnp-3804	305	16	,	,	PUNCT
fnp-3804	305	17	et	et	PROPN
fnp-3804	305	18	al	al	PROPN
fnp-3804	305	19	:	:	PUNCT
fnp-3804	305	20	skull	skull	NOUN
fnp-3804	305	21	and	and	CCONJ
fnp-3804	305	22	vertebral	vertebral	ADJ
fnp-3804	305	23	bone	bone	NOUN
fnp-3804	305	24	marrow	marrow	NOUN
fnp-3804	305	25	are	be	AUX
fnp-3804	305	26	myeloid	myeloid	ADJ
fnp-3804	305	27	cell	cell	NOUN
fnp-3804	305	28	reservoirs	reservoir	NOUN
fnp-3804	305	29	for	for	ADP
fnp-3804	305	30	the	the	DET
fnp-3804	305	31	meninges	meninge	NOUN
fnp-3804	305	32	and	and	CCONJ
fnp-3804	305	33	cns	cns	NOUN
fnp-3804	305	34	parenchyma	parenchyma	NOUN
fnp-3804	305	35	.	.	PUNCT
fnp-3804	306	1	science	science	NOUN
fnp-3804	306	2	373	373	NUM
fnp-3804	306	3	,	,	PUNCT
fnp-3804	306	4	2021	2021	NUM
fnp-3804	306	5	jin	jin	NOUN
fnp-3804	306	6	l	l	PROPN
fnp-3804	306	7	,	,	PUNCT
fnp-3804	306	8	shi	shi	PROPN
fnp-3804	306	9	f	f	PROPN
fnp-3804	306	10	,	,	PUNCT
fnp-3804	306	11	chun	chun	PROPN
fnp-3804	306	12	q	q	PROPN
fnp-3804	306	13	,	,	PUNCT
fnp-3804	306	14	et	et	PROPN
fnp-3804	306	15	al	al	PROPN
fnp-3804	306	16	:	:	PUNCT
fnp-3804	306	17	artificial	artificial	ADJ
fnp-3804	306	18	intelligence	intelligence	NOUN
fnp-3804	306	19	neuropathologist	neuropathologist	NOUN
fnp-3804	306	20	for	for	ADP
fnp-3804	306	21	glioma	glioma	NOUN
fnp-3804	306	22	classification	classification	NOUN
fnp-3804	306	23	using	use	VERB
fnp-3804	306	24	deep	deep	ADJ
fnp-3804	306	25	learning	learning	NOUN
fnp-3804	306	26	on	on	ADP
fnp-3804	306	27	hematoxylin	hematoxylin	NOUN
fnp-3804	306	28	and	and	CCONJ
fnp-3804	306	29	eosin	eosin	NOUN
fnp-3804	306	30	stained	stain	VERB
fnp-3804	306	31	slide	slide	NOUN
fnp-3804	306	32	images	image	NOUN
fnp-3804	306	33	and	and	CCONJ
fnp-3804	306	34	molecular	molecular	ADJ
fnp-3804	306	35	markers	marker	NOUN
fnp-3804	306	36	.	.	PUNCT
fnp-3804	307	1	neuro	neuro	PROPN
fnp-3804	307	2	oncol	oncol	ADJ
fnp-3804	307	3	23:44	23:44	NUM
fnp-3804	307	4	-	-	SYM
fnp-3804	307	5	52	52	NUM
fnp-3804	307	6	,	,	PUNCT
fnp-3804	307	7	2021	2021	NUM
fnp-3804	307	8	copyright	copyright	NOUN
fnp-3804	307	9	:	:	PUNCT
fnp-3804	307	10	©	©	PROPN
fnp-3804	307	11	2022	2022	NUM
fnp-3804	307	12	the	the	DET
fnp-3804	307	13	author(s	author(s	NOUN
fnp-3804	307	14	)	)	PUNCT
fnp-3804	307	15	.	.	PUNCT
fnp-3804	308	1	this	this	PRON
fnp-3804	308	2	is	be	AUX
fnp-3804	308	3	an	an	DET
fnp-3804	308	4	open	open	ADJ
fnp-3804	308	5	access	access	NOUN
fnp-3804	308	6	article	article	NOUN
fnp-3804	308	7	distributed	distribute	VERB
fnp-3804	308	8	under	under	ADP
fnp-3804	308	9	the	the	DET
fnp-3804	308	10	terms	term	NOUN
fnp-3804	308	11	of	of	ADP
fnp-3804	308	12	the	the	DET
fnp-3804	308	13	creative	creative	ADJ
fnp-3804	308	14	commons	common	NOUN
fnp-3804	308	15	attribution	attribution	NOUN
fnp-3804	308	16	4.0	4.0	NUM
fnp-3804	308	17	international	international	ADJ
fnp-3804	308	18	license	license	NOUN
fnp-3804	308	19	(	(	PUNCT
fnp-3804	308	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-3804	308	21	)	)	PUNCT
fnp-3804	308	22	,	,	PUNCT
fnp-3804	308	23	which	which	PRON
fnp-3804	308	24	permits	permit	VERB
fnp-3804	308	25	unrestricted	unrestricted	ADJ
fnp-3804	308	26	use	use	NOUN
fnp-3804	308	27	,	,	PUNCT
fnp-3804	308	28	distribution	distribution	NOUN
fnp-3804	308	29	,	,	PUNCT
fnp-3804	308	30	and	and	CCONJ
fnp-3804	308	31	reproduction	reproduction	NOUN
fnp-3804	308	32	in	in	ADP
fnp-3804	308	33	any	any	DET
fnp-3804	308	34	medium	medium	NOUN
fnp-3804	308	35	,	,	PUNCT
fnp-3804	308	36	provided	provide	VERB
fnp-3804	308	37	the	the	DET
fnp-3804	308	38	original	original	ADJ
fnp-3804	308	39	author	author	NOUN
fnp-3804	308	40	and	and	CCONJ
fnp-3804	308	41	source	source	NOUN
fnp-3804	308	42	are	be	AUX
fnp-3804	308	43	credited	credit	VERB
fnp-3804	308	44	,	,	PUNCT
fnp-3804	308	45	a	a	DET
fnp-3804	308	46	link	link	NOUN
fnp-3804	308	47	to	to	ADP
fnp-3804	308	48	the	the	DET
fnp-3804	308	49	creative	creative	ADJ
fnp-3804	308	50	commons	common	NOUN
fnp-3804	308	51	license	license	NOUN
fnp-3804	308	52	is	be	AUX
fnp-3804	308	53	provided	provide	VERB
fnp-3804	308	54	,	,	PUNCT
fnp-3804	308	55	and	and	CCONJ
fnp-3804	308	56	any	any	DET
fnp-3804	308	57	changes	change	NOUN
fnp-3804	308	58	are	be	AUX
fnp-3804	308	59	indicated	indicate	VERB
fnp-3804	308	60	.	.	PUNCT
fnp-3804	309	1	the	the	DET
fnp-3804	309	2	creative	creative	ADJ
fnp-3804	309	3	commons	common	NOUN
fnp-3804	309	4	public	public	ADJ
fnp-3804	309	5	domain	domain	NOUN
fnp-3804	309	6	dedication	dedication	NOUN
fnp-3804	309	7	waiver	waiver	NOUN
fnp-3804	309	8	(	(	PUNCT
fnp-3804	309	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-3804	309	10	)	)	PUNCT
fnp-3804	309	11	applies	apply	VERB
fnp-3804	309	12	to	to	ADP
fnp-3804	309	13	the	the	DET
fnp-3804	309	14	data	datum	NOUN
fnp-3804	309	15	made	make	VERB
fnp-3804	309	16	available	available	ADJ
fnp-3804	309	17	in	in	ADP
fnp-3804	309	18	this	this	DET
fnp-3804	309	19	article	article	NOUN
fnp-3804	309	20	,	,	PUNCT
fnp-3804	309	21	unless	unless	SCONJ
fnp-3804	309	22	otherwise	otherwise	ADV
fnp-3804	309	23	stated	state	VERB
fnp-3804	309	24	.	.	PUNCT