id	sid	tid	token	lemma	pos
fnp-4682	1	1	neuromuscular	neuromuscular	ADJ
fnp-4682	1	2	disease	disease	NOUN
fnp-4682	1	3	:	:	PUNCT
fnp-4682	1	4	2023	2023	NUM
fnp-4682	1	5	update	update	NOUN
fnp-4682	1	6	feel	feel	VERB
fnp-4682	1	7	free	free	ADJ
fnp-4682	1	8	to	to	PART
fnp-4682	1	9	add	add	VERB
fnp-4682	1	10	comments	comment	NOUN
fnp-4682	1	11	by	by	ADP
fnp-4682	1	12	clicking	click	VERB
fnp-4682	1	13	these	these	DET
fnp-4682	1	14	icons	icon	NOUN
fnp-4682	1	15	on	on	ADP
fnp-4682	1	16	the	the	DET
fnp-4682	1	17	sidebar	sidebar	NOUN
fnp-4682	1	18	free	free	ADJ
fnp-4682	1	19	neuropathology	neuropathology	NOUN
fnp-4682	1	20	4:2	4:2	NUM
fnp-4682	1	21	(	(	PUNCT
fnp-4682	1	22	2023	2023	NUM
fnp-4682	1	23	)	)	PUNCT
fnp-4682	1	24	review	review	VERB
fnp-4682	1	25	neuromuscular	neuromuscular	ADJ
fnp-4682	1	26	disease	disease	NOUN
fnp-4682	1	27	:	:	PUNCT
fnp-4682	1	28	2023	2023	NUM
fnp-4682	1	29	update	update	NOUN
fnp-4682	1	30	marta	marta	PROPN
fnp-4682	1	31	margeta	margeta	PROPN
fnp-4682	1	32	department	department	PROPN
fnp-4682	1	33	of	of	ADP
fnp-4682	1	34	pathology	pathology	PROPN
fnp-4682	1	35	,	,	PUNCT
fnp-4682	1	36	university	university	PROPN
fnp-4682	1	37	of	of	ADP
fnp-4682	1	38	california	california	PROPN
fnp-4682	1	39	,	,	PUNCT
fnp-4682	1	40	san	san	PROPN
fnp-4682	1	41	francisco	francisco	PROPN
fnp-4682	1	42	,	,	PUNCT
fnp-4682	1	43	ca	ca	PROPN
fnp-4682	1	44	,	,	PUNCT
fnp-4682	1	45	usa	usa	PROPN
fnp-4682	1	46	corresponding	corresponding	PROPN
fnp-4682	1	47	author	author	NOUN
fnp-4682	1	48	:	:	PUNCT
fnp-4682	1	49	marta	marta	PROPN
fnp-4682	1	50	margeta	margeta	PROPN
fnp-4682	1	51	·	·	PUNCT
fnp-4682	1	52	ucsf	ucsf	PROPN
fnp-4682	1	53	pathology	pathology	PROPN
fnp-4682	1	54	,	,	PUNCT
fnp-4682	1	55	box	box	PROPN
fnp-4682	1	56	0511	0511	NUM
fnp-4682	1	57	·	·	PUNCT
fnp-4682	2	1	513	513	NUM
fnp-4682	2	2	parnassus	parnassus	PROPN
fnp-4682	2	3	ave	ave	PROPN
fnp-4682	2	4	.	.	PROPN
fnp-4682	2	5	,	,	PUNCT
fnp-4682	2	6	hsw-514	hsw-514	NOUN
fnp-4682	2	7	·	·	PUNCT
fnp-4682	2	8	san	san	PROPN
fnp-4682	2	9	francisco	francisco	PROPN
fnp-4682	2	10	,	,	PUNCT
fnp-4682	2	11	ca	ca	PROPN
fnp-4682	2	12	94143	94143	NUM
fnp-4682	2	13	·	·	PUNCT
fnp-4682	3	1	usa	usa	PROPN
fnp-4682	3	2	marta.margeta@ucsf.edu	marta.margeta@ucsf.edu	PROPN
fnp-4682	3	3	submitted	submit	VERB
fnp-4682	3	4	:	:	PUNCT
fnp-4682	3	5	07	07	NUM
fnp-4682	3	6	february	february	PROPN
fnp-4682	3	7	2023	2023	NUM
fnp-4682	3	8	accepted	accept	VERB
fnp-4682	3	9	:	:	PUNCT
fnp-4682	3	10	22	22	NUM
fnp-4682	3	11	february	february	NOUN
fnp-4682	3	12	2023	2023	NUM
fnp-4682	3	13	copyedited	copyedit	VERB
fnp-4682	3	14	by	by	ADP
fnp-4682	3	15	:	:	PUNCT
fnp-4682	3	16	biswa	biswa	PROPN
fnp-4682	3	17	ramani	ramani	PROPN
fnp-4682	3	18	published	publish	VERB
fnp-4682	3	19	:	:	PUNCT
fnp-4682	3	20	27	27	NUM
fnp-4682	3	21	february	february	NOUN
fnp-4682	3	22	2023	2023	NUM
fnp-4682	3	23	https://doi.org/10.17879/freeneuropathology-2023-4682	https://doi.org/10.17879/freeneuropathology-2023-4682	NOUN
fnp-4682	3	24	keywords	keyword	NOUN
fnp-4682	3	25	:	:	PUNCT
fnp-4682	3	26	long	long	ADJ
fnp-4682	3	27	covid	covid	PROPN
fnp-4682	3	28	,	,	PUNCT
fnp-4682	3	29	guillain	guillain	NOUN
fnp-4682	3	30	-	-	PUNCT
fnp-4682	3	31	barré	barré	PROPN
fnp-4682	3	32	syndrome	syndrome	NOUN
fnp-4682	3	33	,	,	PUNCT
fnp-4682	3	34	wallerian	wallerian	ADJ
fnp-4682	3	35	degeneration	degeneration	NOUN
fnp-4682	3	36	,	,	PUNCT
fnp-4682	3	37	nodes	node	NOUN
fnp-4682	3	38	of	of	ADP
fnp-4682	3	39	ranvier	ranvier	NOUN
fnp-4682	3	40	,	,	PUNCT
fnp-4682	3	41	muscle	muscle	NOUN
fnp-4682	3	42	regeneration	regeneration	NOUN
fnp-4682	3	43	,	,	PUNCT
fnp-4682	3	44	chaperonopathy	chaperonopathy	ADJ
fnp-4682	3	45	,	,	PUNCT
fnp-4682	3	46	target	target	NOUN
fnp-4682	3	47	fiber	fiber	NOUN
fnp-4682	3	48	,	,	PUNCT
fnp-4682	3	49	inclusion	inclusion	NOUN
fnp-4682	3	50	body	body	NOUN
fnp-4682	3	51	myositis	myositis	NOUN
fnp-4682	3	52	,	,	PUNCT
fnp-4682	3	53	facioscapulohumeral	facioscapulohumeral	ADJ
fnp-4682	3	54	dystrophy	dystrophy	NOUN
fnp-4682	3	55	,	,	PUNCT
fnp-4682	3	56	myotonic	myotonic	ADJ
fnp-4682	3	57	dystrophy	dystrophy	NOUN
fnp-4682	3	58	,	,	PUNCT
fnp-4682	3	59	amyotrophic	amyotrophic	ADJ
fnp-4682	3	60	lateral	lateral	ADJ
fnp-4682	3	61	sclerosis	sclerosis	NOUN
fnp-4682	3	62	abstract	abstract	NOUN
fnp-4682	3	63	this	this	DET
fnp-4682	3	64	review	review	NOUN
fnp-4682	3	65	highlights	highlight	VERB
fnp-4682	3	66	ten	ten	NUM
fnp-4682	3	67	important	important	ADJ
fnp-4682	3	68	advances	advance	NOUN
fnp-4682	3	69	in	in	ADP
fnp-4682	3	70	the	the	DET
fnp-4682	3	71	neuromuscular	neuromuscular	ADJ
fnp-4682	3	72	disease	disease	NOUN
fnp-4682	3	73	field	field	NOUN
fnp-4682	3	74	that	that	PRON
fnp-4682	3	75	were	be	AUX
fnp-4682	3	76	reported	report	VERB
fnp-4682	3	77	in	in	ADP
fnp-4682	3	78	2022	2022	NUM
fnp-4682	3	79	.	.	PUNCT
fnp-4682	4	1	as	as	ADP
fnp-4682	4	2	with	with	ADP
fnp-4682	4	3	prior	prior	ADJ
fnp-4682	4	4	updates	update	NOUN
fnp-4682	4	5	in	in	ADP
fnp-4682	4	6	this	this	DET
fnp-4682	4	7	article	article	NOUN
fnp-4682	4	8	series	series	NOUN
fnp-4682	4	9	,	,	PUNCT
fnp-4682	4	10	the	the	DET
fnp-4682	4	11	overarching	overarching	ADJ
fnp-4682	4	12	topics	topic	NOUN
fnp-4682	4	13	include	include	VERB
fnp-4682	4	14	(	(	PUNCT
fnp-4682	4	15	i	i	NOUN
fnp-4682	4	16	)	)	PUNCT
fnp-4682	4	17	advances	advance	NOUN
fnp-4682	4	18	in	in	ADP
fnp-4682	4	19	understanding	understanding	NOUN
fnp-4682	4	20	of	of	ADP
fnp-4682	4	21	fundamental	fundamental	ADJ
fnp-4682	4	22	neuromuscular	neuromuscular	ADJ
fnp-4682	4	23	biology	biology	NOUN
fnp-4682	4	24	;	;	PUNCT
fnp-4682	4	25	(	(	PUNCT
fnp-4682	4	26	ii	ii	NOUN
fnp-4682	4	27	)	)	PUNCT
fnp-4682	4	28	new	new	ADJ
fnp-4682	4	29	/	/	SYM
fnp-4682	4	30	emerging	emerge	VERB
fnp-4682	4	31	diseases	disease	NOUN
fnp-4682	4	32	;	;	PUNCT
fnp-4682	4	33	(	(	PUNCT
fnp-4682	4	34	iii	iii	X
fnp-4682	4	35	)	)	PUNCT
fnp-4682	4	36	advances	advance	NOUN
fnp-4682	4	37	in	in	ADP
fnp-4682	4	38	understanding	understanding	NOUN
fnp-4682	4	39	of	of	ADP
fnp-4682	4	40	disease	disease	NOUN
fnp-4682	4	41	etiology	etiology	NOUN
fnp-4682	4	42	and	and	CCONJ
fnp-4682	4	43	pathogenesis	pathogenesis	NOUN
fnp-4682	4	44	;	;	PUNCT
fnp-4682	4	45	(	(	PUNCT
fnp-4682	4	46	iv	iv	X
fnp-4682	4	47	)	)	PUNCT
fnp-4682	4	48	diagnostic	diagnostic	ADJ
fnp-4682	4	49	advances	advance	NOUN
fnp-4682	4	50	;	;	PUNCT
fnp-4682	4	51	and	and	CCONJ
fnp-4682	4	52	(	(	PUNCT
fnp-4682	4	53	v	v	NOUN
fnp-4682	4	54	)	)	PUNCT
fnp-4682	4	55	therapeutic	therapeutic	ADJ
fnp-4682	4	56	advances	advance	NOUN
fnp-4682	4	57	.	.	PUNCT
fnp-4682	5	1	within	within	ADP
fnp-4682	5	2	this	this	DET
fnp-4682	5	3	general	general	ADJ
fnp-4682	5	4	framework	framework	NOUN
fnp-4682	5	5	,	,	PUNCT
fnp-4682	5	6	the	the	DET
fnp-4682	5	7	individual	individual	ADJ
fnp-4682	5	8	disease	disease	NOUN
fnp-4682	5	9	entities	entity	NOUN
fnp-4682	5	10	that	that	PRON
fnp-4682	5	11	are	be	AUX
fnp-4682	5	12	discussed	discuss	VERB
fnp-4682	5	13	in	in	ADP
fnp-4682	5	14	more	more	ADJ
fnp-4682	5	15	detail	detail	NOUN
fnp-4682	5	16	include	include	VERB
fnp-4682	5	17	neuromuscular	neuromuscular	ADJ
fnp-4682	5	18	complications	complication	NOUN
fnp-4682	5	19	of	of	ADP
fnp-4682	5	20	covid-19	covid-19	PROPN
fnp-4682	5	21	(	(	PUNCT
fnp-4682	5	22	another	another	DET
fnp-4682	5	23	look	look	NOUN
fnp-4682	5	24	at	at	ADP
fnp-4682	5	25	the	the	DET
fnp-4682	5	26	topic	topic	NOUN
fnp-4682	5	27	first	first	ADV
fnp-4682	5	28	covered	cover	VERB
fnp-4682	5	29	in	in	ADP
fnp-4682	5	30	the	the	DET
fnp-4682	5	31	2021	2021	NUM
fnp-4682	5	32	and	and	CCONJ
fnp-4682	5	33	2022	2022	NUM
fnp-4682	5	34	reviews	review	NOUN
fnp-4682	5	35	)	)	PUNCT
fnp-4682	5	36	,	,	PUNCT
fnp-4682	5	37	dnajb4	dnajb4	PROPN
fnp-4682	5	38	-	-	PUNCT
fnp-4682	5	39	associated	associate	VERB
fnp-4682	5	40	myopathy	myopathy	ADJ
fnp-4682	5	41	,	,	PUNCT
fnp-4682	5	42	nmnat2	nmnat2	NOUN
fnp-4682	5	43	-	-	PUNCT
fnp-4682	5	44	deficient	deficient	ADJ
fnp-4682	5	45	hereditary	hereditary	ADJ
fnp-4682	5	46	axonal	axonal	ADJ
fnp-4682	5	47	neuropathy	neuropathy	ADJ
fnp-4682	5	48	,	,	PUNCT
fnp-4682	5	49	guillain	guillain	NOUN
fnp-4682	5	50	-	-	PUNCT
fnp-4682	5	51	barré	barré	PROPN
fnp-4682	5	52	syndrome	syndrome	NOUN
fnp-4682	5	53	,	,	PUNCT
fnp-4682	5	54	sporadic	sporadic	ADJ
fnp-4682	5	55	inclusion	inclusion	NOUN
fnp-4682	5	56	body	body	NOUN
fnp-4682	5	57	myositis	myositis	NOUN
fnp-4682	5	58	,	,	PUNCT
fnp-4682	5	59	and	and	CCONJ
fnp-4682	5	60	amyotrophic	amyotrophic	ADJ
fnp-4682	5	61	lateral	lateral	ADJ
fnp-4682	5	62	sclerosis	sclerosis	NOUN
fnp-4682	5	63	.	.	PUNCT
fnp-4682	6	1	in	in	ADP
fnp-4682	6	2	addition	addition	NOUN
fnp-4682	6	3	,	,	PUNCT
fnp-4682	6	4	the	the	DET
fnp-4682	6	5	review	review	NOUN
fnp-4682	6	6	highlights	highlight	VERB
fnp-4682	6	7	a	a	DET
fnp-4682	6	8	few	few	ADJ
fnp-4682	6	9	other	other	ADJ
fnp-4682	6	10	advances	advance	NOUN
fnp-4682	6	11	(	(	PUNCT
fnp-4682	6	12	including	include	VERB
fnp-4682	6	13	new	new	ADJ
fnp-4682	6	14	insights	insight	NOUN
fnp-4682	6	15	into	into	ADP
fnp-4682	6	16	mechanisms	mechanism	NOUN
fnp-4682	6	17	of	of	ADP
fnp-4682	6	18	fiber	fiber	NOUN
fnp-4682	6	19	maturation	maturation	NOUN
fnp-4682	6	20	during	during	ADP
fnp-4682	6	21	muscle	muscle	NOUN
fnp-4682	6	22	regeneration	regeneration	NOUN
fnp-4682	6	23	and	and	CCONJ
fnp-4682	6	24	fiber	fiber	NOUN
fnp-4682	6	25	rebuilding	rebuild	VERB
fnp-4682	6	26	following	follow	VERB
fnp-4682	6	27	reinnervation	reinnervation	NOUN
fnp-4682	6	28	,	,	PUNCT
fnp-4682	6	29	improved	improve	VERB
fnp-4682	6	30	genetic	genetic	ADJ
fnp-4682	6	31	testing	testing	NOUN
fnp-4682	6	32	methods	method	NOUN
fnp-4682	6	33	for	for	ADP
fnp-4682	6	34	facioscapulohumeral	facioscapulohumeral	ADJ
fnp-4682	6	35	and	and	CCONJ
fnp-4682	6	36	myotonic	myotonic	ADJ
fnp-4682	6	37	muscular	muscular	ADJ
fnp-4682	6	38	dystrophies	dystrophy	NOUN
fnp-4682	6	39	,	,	PUNCT
fnp-4682	6	40	and	and	CCONJ
fnp-4682	6	41	the	the	DET
fnp-4682	6	42	use	use	NOUN
fnp-4682	6	43	of	of	ADP
fnp-4682	6	44	sarm1	sarm1	PROPN
fnp-4682	6	45	inhibitors	inhibitor	NOUN
fnp-4682	6	46	to	to	PART
fnp-4682	6	47	block	block	VERB
fnp-4682	6	48	wallerian	wallerian	NOUN
fnp-4682	6	49	degeneration	degeneration	NOUN
fnp-4682	6	50	)	)	PUNCT
fnp-4682	6	51	that	that	PRON
fnp-4682	6	52	will	will	AUX
fnp-4682	6	53	be	be	AUX
fnp-4682	6	54	of	of	ADP
fnp-4682	6	55	significant	significant	ADJ
fnp-4682	6	56	interest	interest	NOUN
fnp-4682	6	57	for	for	ADP
fnp-4682	6	58	clinicians	clinician	NOUN
fnp-4682	6	59	and	and	CCONJ
fnp-4682	6	60	researchers	researcher	NOUN
fnp-4682	6	61	who	who	PRON
fnp-4682	6	62	specialize	specialize	VERB
fnp-4682	6	63	in	in	ADP
fnp-4682	6	64	neuromuscular	neuromuscular	ADJ
fnp-4682	6	65	disease	disease	NOUN
fnp-4682	6	66	.	.	PUNCT
fnp-4682	7	1	abbreviations	abbreviation	NOUN
fnp-4682	7	2	ad	ad	NOUN
fnp-4682	7	3	autosomal	autosomal	ADJ
fnp-4682	7	4	dominant	dominant	NOUN
fnp-4682	7	5	,	,	PUNCT
fnp-4682	7	6	adpr	adpr	NOUN
fnp-4682	7	7	adenosine	adenosine	VERB
fnp-4682	7	8	diphosphate	diphosphate	NOUN
fnp-4682	7	9	ribose	ribose	NOUN
fnp-4682	7	10	,	,	PUNCT
fnp-4682	7	11	aidp	aidp	NOUN
fnp-4682	7	12	acute	acute	NOUN
fnp-4682	7	13	inflammatory	inflammatory	ADJ
fnp-4682	7	14	demyelinating	demyelinate	VERB
fnp-4682	7	15	polyneuropathy	polyneuropathy	NOUN
fnp-4682	7	16	,	,	PUNCT
fnp-4682	7	17	als	als	VERB
fnp-4682	7	18	amyotrophic	amyotrophic	ADJ
fnp-4682	7	19	lateral	lateral	ADJ
fnp-4682	7	20	sclerosis	sclerosis	NOUN
fnp-4682	7	21	,	,	PUNCT
fnp-4682	7	22	aman	aman	NOUN
fnp-4682	7	23	acute	acute	PROPN
fnp-4682	7	24	motor	motor	PROPN
fnp-4682	7	25	axonal	axonal	ADJ
fnp-4682	7	26	neuropathy	neuropathy	ADJ
fnp-4682	7	27	,	,	PUNCT
fnp-4682	7	28	amsan	amsan	ADJ
fnp-4682	7	29	acute	acute	PROPN
fnp-4682	7	30	multifocal	multifocal	ADJ
fnp-4682	7	31	sensorimotor	sensorimotor	NOUN
fnp-4682	7	32	neuropathy	neuropathy	ADJ
fnp-4682	7	33	,	,	PUNCT
fnp-4682	7	34	ar	ar	NOUN
fnp-4682	7	35	autosomal	autosomal	ADJ
fnp-4682	7	36	recessive	recessive	ADJ
fnp-4682	7	37	,	,	PUNCT
fnp-4682	7	38	cnm	cnm	PROPN
fnp-4682	7	39	centronuclear	centronuclear	PROPN
fnp-4682	7	40	myopathy	myopathy	ADJ
fnp-4682	7	41	,	,	PUNCT
fnp-4682	7	42	cox	cox	PROPN
fnp-4682	7	43	cytochrome	cytochrome	PROPN
fnp-4682	7	44	c	c	PROPN
fnp-4682	7	45	oxidase	oxidase	NOUN
fnp-4682	7	46	,	,	PUNCT
fnp-4682	7	47	covid-19	covid-19	PROPN
fnp-4682	7	48	coronavirus	coronavirus	NOUN
fnp-4682	7	49	disease	disease	NOUN
fnp-4682	7	50	2019	2019	NUM
fnp-4682	7	51	,	,	PUNCT
fnp-4682	7	52	dm	dm	AUX
fnp-4682	7	53	dystrophia	dystrophia	VERB
fnp-4682	7	54	myotonica	myotonica	PROPN
fnp-4682	7	55	(	(	PUNCT
fnp-4682	7	56	myotonic	myotonic	ADJ
fnp-4682	7	57	dystrophy	dystrophy	NOUN
fnp-4682	7	58	)	)	PUNCT
fnp-4682	7	59	,	,	PUNCT
fnp-4682	7	60	emg	emg	NOUN
fnp-4682	7	61	electromyography	electromyography	NOUN
fnp-4682	7	62	,	,	PUNCT
fnp-4682	7	63	fshd	fshd	ADJ
fnp-4682	7	64	facioscapulohumeral	facioscapulohumeral	ADJ
fnp-4682	7	65	dystrophy	dystrophy	NOUN
fnp-4682	7	66	,	,	PUNCT
fnp-4682	7	67	gbs	gbs	PROPN
fnp-4682	7	68	guillain	guillain	PROPN
fnp-4682	7	69	-	-	PUNCT
fnp-4682	7	70	barré	barré	PROPN
fnp-4682	7	71	syndrome	syndrome	PROPN
fnp-4682	7	72	,	,	PUNCT
fnp-4682	7	73	iefnd	iefnd	ADJ
fnp-4682	7	74	intraep	intraep	ADJ
fnp-4682	7	75	-	-	PUNCT
fnp-4682	7	76	idermal	idermal	ADJ
fnp-4682	7	77	nerve	nerve	NOUN
fnp-4682	7	78	fiber	fiber	NOUN
fnp-4682	7	79	density	density	NOUN
fnp-4682	7	80	,	,	PUNCT
fnp-4682	7	81	ivig	ivig	NOUN
fnp-4682	7	82	intravenous	intravenous	ADJ
fnp-4682	7	83	immunoglobulin	immunoglobulin	NOUN
fnp-4682	7	84	,	,	PUNCT
fnp-4682	7	85	lmn	lmn	PROPN
fnp-4682	7	86	lower	low	ADJ
fnp-4682	7	87	motor	motor	NOUN
fnp-4682	7	88	neuron	neuron	PROPN
fnp-4682	7	89	,	,	PUNCT
fnp-4682	7	90	mac	mac	PROPN
fnp-4682	7	91	membrane	membrane	NOUN
fnp-4682	7	92	attack	attack	NOUN
fnp-4682	7	93	complex	complex	NOUN
fnp-4682	7	94	,	,	PUNCT
fnp-4682	7	95	mfn2	mfn2	PROPN
fnp-4682	7	96	mitofusin	mitofusin	PROPN
fnp-4682	7	97	2	2	NUM
fnp-4682	7	98	,	,	PUNCT
fnp-4682	7	99	mhc	mhc	PROPN
fnp-4682	7	100	-	-	PUNCT
fnp-4682	7	101	i	i	PRON
fnp-4682	7	102	major	major	ADJ
fnp-4682	7	103	histocompatibility	histocompatibility	NOUN
fnp-4682	7	104	complex	complex	NOUN
fnp-4682	7	105	i	i	PROPN
fnp-4682	7	106	,	,	PUNCT
fnp-4682	7	107	mnd	mnd	PROPN
fnp-4682	7	108	motor	motor	PROPN
fnp-4682	7	109	neuron	neuron	PROPN
fnp-4682	7	110	disease	disease	PROPN
fnp-4682	7	111	,	,	PUNCT
fnp-4682	7	112	myhc	myhc	PROPN
fnp-4682	7	113	myosin	myosin	PROPN
fnp-4682	7	114	heavy	heavy	PROPN
fnp-4682	7	115	chain	chain	NOUN
fnp-4682	7	116	,	,	PUNCT
fnp-4682	7	117	ncs	ncs	PROPN
fnp-4682	7	118	nerve	nerve	NOUN
fnp-4682	7	119	conduction	conduction	NOUN
fnp-4682	7	120	studies	study	NOUN
fnp-4682	7	121	,	,	PUNCT
fnp-4682	7	122	nor	nor	CCONJ
fnp-4682	7	123	node(s	node(s	ADJ
fnp-4682	7	124	)	)	PUNCT
fnp-4682	7	125	of	of	ADP
fnp-4682	7	126	ranvier	ranvier	NOUN
fnp-4682	7	127	,	,	PUNCT
fnp-4682	7	128	pasc	pasc	ADJ
fnp-4682	7	129	post	post	ADJ
fnp-4682	7	130	-	-	ADJ
fnp-4682	7	131	acute	acute	ADJ
fnp-4682	7	132	sequalae	sequalae	NOUN
fnp-4682	7	133	of	of	ADP
fnp-4682	7	134	sars	sar	NOUN
fnp-4682	7	135	-	-	PUNCT
fnp-4682	7	136	cov-2	cov-2	PART
fnp-4682	7	137	infection	infection	NOUN
fnp-4682	7	138	,	,	PUNCT
fnp-4682	7	139	pm	pm	PROPN
fnp-4682	7	140	-	-	PUNCT
fnp-4682	7	141	mito	mito	PROPN
fnp-4682	7	142	polymyositis	polymyositis	PROPN
fnp-4682	7	143	with	with	ADP
fnp-4682	7	144	mitochondrial	mitochondrial	ADJ
fnp-4682	7	145	abnormalities	abnormality	NOUN
fnp-4682	7	146	,	,	PUNCT
fnp-4682	7	147	sc	sc	PROPN
fnp-4682	7	148	schwann	schwann	PROPN
fnp-4682	7	149	cell	cell	PROPN
fnp-4682	7	150	,	,	PUNCT
fnp-4682	7	151	sfn	sfn	PROPN
fnp-4682	7	152	small	small	ADJ
fnp-4682	7	153	fiber	fiber	NOUN
fnp-4682	7	154	neuropathy	neuropathy	ADJ
fnp-4682	7	155	,	,	PUNCT
fnp-4682	7	156	sibm	sibm	PROPN
fnp-4682	7	157	sporadic	sporadic	ADJ
fnp-4682	7	158	inclusion	inclusion	NOUN
fnp-4682	7	159	body	body	NOUN
fnp-4682	7	160	myositis	myositis	NOUN
fnp-4682	7	161	,	,	PUNCT
fnp-4682	7	162	str	str	VERB
fnp-4682	7	163	short	short	ADJ
fnp-4682	7	164	tandem	tandem	PROPN
fnp-4682	7	165	repeat	repeat	NOUN
fnp-4682	7	166	,	,	PUNCT
fnp-4682	7	167	xlmtm	xlmtm	PROPN
fnp-4682	7	168	x	x	VERB
fnp-4682	7	169	-	-	VERB
fnp-4682	7	170	linked	link	VERB
fnp-4682	7	171	myotubular	myotubular	ADJ
fnp-4682	7	172	myopathy	myopathy	NOUN
fnp-4682	7	173	in	in	ADP
fnp-4682	7	174	this	this	DET
fnp-4682	7	175	annual	annual	ADJ
fnp-4682	7	176	update	update	NOUN
fnp-4682	7	177	,	,	PUNCT
fnp-4682	7	178	i	i	PRON
fnp-4682	7	179	will	will	AUX
fnp-4682	7	180	briefly	briefly	ADV
fnp-4682	7	181	describe	describe	VERB
fnp-4682	7	182	ten	ten	NUM
fnp-4682	7	183	neuromuscular	neuromuscular	ADJ
fnp-4682	7	184	field	field	NOUN
fnp-4682	7	185	advances	advance	NOUN
fnp-4682	7	186	from	from	ADP
fnp-4682	7	187	2022	2022	NUM
fnp-4682	7	188	that	that	PRON
fnp-4682	7	189	i	i	PRON
fnp-4682	7	190	consider	consider	VERB
fnp-4682	7	191	to	to	PART
fnp-4682	7	192	be	be	AUX
fnp-4682	7	193	most	most	ADV
fnp-4682	7	194	important	important	ADJ
fnp-4682	7	195	and/or	and/or	CCONJ
fnp-4682	7	196	interesting	interesting	ADJ
fnp-4682	7	197	;	;	PUNCT
fnp-4682	7	198	as	as	ADP
fnp-4682	7	199	in	in	ADP
fnp-4682	7	200	the	the	DET
fnp-4682	7	201	prior	prior	ADJ
fnp-4682	7	202	updates	update	NOUN
fnp-4682	7	203	(	(	PUNCT
fnp-4682	7	204	margeta	margeta	NOUN
fnp-4682	7	205	,	,	PUNCT
fnp-4682	7	206	2020	2020	NUM
fnp-4682	7	207	,	,	PUNCT
fnp-4682	7	208	2021	2021	NUM
fnp-4682	7	209	,	,	PUNCT
fnp-4682	7	210	2022	2022	NUM
fnp-4682	7	211	)	)	PUNCT
fnp-4682	7	212	,	,	PUNCT
fnp-4682	7	213	these	these	DET
fnp-4682	7	214	advances	advance	NOUN
fnp-4682	7	215	will	will	AUX
fnp-4682	7	216	be	be	AUX
fnp-4682	7	217	grouped	group	VERB
fnp-4682	7	218	into	into	ADP
fnp-4682	7	219	different	different	ADJ
fnp-4682	7	220	“	"	PUNCT
fnp-4682	7	221	discovery	discovery	NOUN
fnp-4682	7	222	clusters	cluster	NOUN
fnp-4682	7	223	”	"	PUNCT
fnp-4682	7	224	and	and	CCONJ
fnp-4682	7	225	listed	list	VERB
fnp-4682	7	226	in	in	ADP
fnp-4682	7	227	no	no	DET
fnp-4682	7	228	particular	particular	ADJ
fnp-4682	7	229	order	order	NOUN
fnp-4682	7	230	.	.	PUNCT
fnp-4682	8	1	advances	advance	NOUN
fnp-4682	8	2	in	in	ADP
fnp-4682	8	3	fundamental	fundamental	ADJ
fnp-4682	8	4	neuromuscular	neuromuscular	ADJ
fnp-4682	8	5	biology	biology	NOUN
fnp-4682	8	6	with	with	ADP
fnp-4682	8	7	implications	implication	NOUN
fnp-4682	8	8	for	for	ADP
fnp-4682	8	9	neuromuscular	neuromuscular	ADJ
fnp-4682	8	10	disease	disease	NOUN
fnp-4682	8	11	1	1	NUM
fnp-4682	8	12	.	.	PUNCT
fnp-4682	9	1	regulation	regulation	NOUN
fnp-4682	9	2	of	of	ADP
fnp-4682	9	3	the	the	DET
fnp-4682	9	4	neonatal	neonatal	ADJ
fnp-4682	9	5	-	-	PUNCT
fnp-4682	9	6	adult	adult	NOUN
fnp-4682	9	7	maturation	maturation	NOUN
fnp-4682	9	8	checkpoint	checkpoint	NOUN
fnp-4682	9	9	during	during	ADP
fnp-4682	9	10	skeletal	skeletal	ADJ
fnp-4682	9	11	muscle	muscle	NOUN
fnp-4682	9	12	regeneration	regeneration	NOUN
fnp-4682	9	13	in	in	ADP
fnp-4682	9	14	the	the	DET
fnp-4682	9	15	past	past	ADJ
fnp-4682	9	16	two	two	NUM
fnp-4682	9	17	reviews	review	NOUN
fnp-4682	9	18	(	(	PUNCT
fnp-4682	9	19	margeta	margeta	NOUN
fnp-4682	9	20	,	,	PUNCT
fnp-4682	9	21	2021	2021	NUM
fnp-4682	9	22	,	,	PUNCT
fnp-4682	9	23	2022	2022	NUM
fnp-4682	9	24	)	)	PUNCT
fnp-4682	10	1	,	,	PUNCT
fnp-4682	10	2	i	i	PRON
fnp-4682	10	3	described	describe	VERB
fnp-4682	10	4	the	the	DET
fnp-4682	10	5	crosstalk	crosstalk	NOUN
fnp-4682	10	6	between	between	ADP
fnp-4682	10	7	macrophages	macrophage	NOUN
fnp-4682	10	8	and	and	CCONJ
fnp-4682	10	9	satellite	satellite	NOUN
fnp-4682	10	10	cells	cell	NOUN
fnp-4682	10	11	(	(	PUNCT
fnp-4682	10	12	muscle	muscle	NOUN
fnp-4682	10	13	stem	stem	NOUN
fnp-4682	10	14	cells	cell	NOUN
fnp-4682	10	15	)	)	PUNCT
fnp-4682	10	16	that	that	PRON
fnp-4682	10	17	initiates	initiate	VERB
fnp-4682	10	18	skeletal	skeletal	ADJ
fnp-4682	10	19	muscle	muscle	NOUN
fnp-4682	10	20	repair	repair	NOUN
fnp-4682	10	21	.	.	PUNCT
fnp-4682	11	1	in	in	ADP
fnp-4682	11	2	this	this	DET
fnp-4682	11	3	review	review	NOUN
fnp-4682	11	4	,	,	PUNCT
fnp-4682	11	5	the	the	DET
fnp-4682	11	6	focus	focus	NOUN
fnp-4682	11	7	will	will	AUX
fnp-4682	11	8	be	be	AUX
fnp-4682	11	9	on	on	ADP
fnp-4682	11	10	a	a	DET
fnp-4682	11	11	later	later	ADJ
fnp-4682	11	12	stage	stage	NOUN
fnp-4682	11	13	of	of	ADP
fnp-4682	11	14	myofiber	myofiber	ADJ
fnp-4682	11	15	regeneration	regeneration	NOUN
fnp-4682	11	16	,	,	PUNCT
fnp-4682	11	17	which	which	PRON
fnp-4682	11	18	recapitulates	recapitulate	VERB
fnp-4682	11	19	muscle	muscle	NOUN
fnp-4682	11	20	development	development	NOUN
fnp-4682	11	21	and	and	CCONJ
fnp-4682	11	22	involves	involve	VERB
fnp-4682	11	23	myofiber	myofiber	ADJ
fnp-4682	11	24	growth	growth	NOUN
fnp-4682	11	25	and	and	CCONJ
fnp-4682	11	26	maturation	maturation	NOUN
fnp-4682	11	27	from	from	ADP
fnp-4682	11	28	a	a	DET
fnp-4682	11	29	fetal	fetal	NOUN
fnp-4682	11	30	to	to	ADP
fnp-4682	11	31	the	the	DET
fnp-4682	11	32	adult	adult	NOUN
fnp-4682	11	33	state	state	NOUN
fnp-4682	11	34	.	.	PUNCT
fnp-4682	12	1	in	in	ADP
fnp-4682	12	2	mammals	mammal	NOUN
fnp-4682	12	3	,	,	PUNCT
fnp-4682	12	4	there	there	PRON
fnp-4682	12	5	are	be	VERB
fnp-4682	12	6	seven	seven	NUM
fnp-4682	12	7	distinct	distinct	ADJ
fnp-4682	12	8	isoforms	isoform	NOUN
fnp-4682	12	9	of	of	ADP
fnp-4682	12	10	myosin	myosin	PROPN
fnp-4682	12	11	heavy	heavy	PROPN
fnp-4682	12	12	chain	chain	NOUN
fnp-4682	12	13	(	(	PUNCT
fnp-4682	12	14	myhc	myhc	PROPN
fnp-4682	12	15	;	;	PUNCT
fnp-4682	12	16	the	the	DET
fnp-4682	12	17	major	major	ADJ
fnp-4682	12	18	contractile	contractile	NOUN
fnp-4682	12	19	component	component	NOUN
fnp-4682	12	20	of	of	ADP
fnp-4682	12	21	thick	thick	ADJ
fnp-4682	12	22	filaments	filament	NOUN
fnp-4682	12	23	)	)	PUNCT
fnp-4682	12	24	–	–	PUNCT
fnp-4682	12	25	two	two	NUM
fnp-4682	12	26	isoforms	isoform	NOUN
fnp-4682	12	27	that	that	PRON
fnp-4682	12	28	are	be	AUX
fnp-4682	12	29	normally	normally	ADV
fnp-4682	12	30	expressed	express	VERB
fnp-4682	12	31	only	only	ADV
fnp-4682	12	32	during	during	ADP
fnp-4682	12	33	development	development	NOUN
fnp-4682	12	34	[	[	X
fnp-4682	12	35	embryonic	embryonic	ADJ
fnp-4682	12	36	(	(	PUNCT
fnp-4682	12	37	myhc	myhc	PROPN
fnp-4682	12	38	-	-	PUNCT
fnp-4682	12	39	emb	emb	PROPN
fnp-4682	12	40	/	/	SYM
fnp-4682	12	41	mhc3	mhc3	PROPN
fnp-4682	12	42	)	)	PUNCT
fnp-4682	12	43	and	and	CCONJ
fnp-4682	12	44	neonatal	neonatal	ADJ
fnp-4682	12	45	(	(	PUNCT
fnp-4682	12	46	myhc	myhc	PROPN
fnp-4682	12	47	-	-	PUNCT
fnp-4682	12	48	neo	neo	PROPN
fnp-4682	12	49	/	/	SYM
fnp-4682	12	50	mhc8	mhc8	NOUN
fnp-4682	12	51	)	)	PUNCT
fnp-4682	12	52	]	]	PUNCT
fnp-4682	12	53	and	and	CCONJ
fnp-4682	12	54	four	four	NUM
fnp-4682	12	55	isoforms	isoform	NOUN
fnp-4682	12	56	that	that	PRON
fnp-4682	12	57	are	be	AUX
fnp-4682	12	58	expressed	express	VERB
fnp-4682	12	59	in	in	ADP
fnp-4682	12	60	mature	mature	ADJ
fnp-4682	12	61	muscle	muscle	NOUN
fnp-4682	12	62	fibers	fiber	NOUN
fnp-4682	12	63	[	[	X
fnp-4682	12	64	one	one	NUM
fnp-4682	12	65	slow	slow	ADJ
fnp-4682	12	66	isoform	isoform	NOUN
fnp-4682	12	67	(	(	PUNCT
fnp-4682	12	68	mhc	mhc	NOUN
fnp-4682	12	69	-	-	PUNCT
fnp-4682	12	70	slow	slow	ADJ
fnp-4682	12	71	/	/	SYM
fnp-4682	12	72	mhc7	mhc7	NOUN
fnp-4682	12	73	;	;	PUNCT
fnp-4682	12	74	type	type	NOUN
fnp-4682	12	75	1	1	NUM
fnp-4682	12	76	fibers	fiber	NOUN
fnp-4682	12	77	)	)	PUNCT
fnp-4682	12	78	and	and	CCONJ
fnp-4682	12	79	three	three	NUM
fnp-4682	12	80	fast	fast	ADJ
fnp-4682	12	81	isoforms	isoform	NOUN
fnp-4682	12	82	:	:	PUNCT
fnp-4682	12	83	myhc-2a	myhc-2a	NUM
fnp-4682	12	84	/	/	SYM
fnp-4682	12	85	mhc2	mhc2	PROPN
fnp-4682	12	86	(	(	PUNCT
fnp-4682	12	87	type	type	NOUN
fnp-4682	12	88	2a	2a	NUM
fnp-4682	12	89	fibers	fiber	NOUN
fnp-4682	12	90	)	)	PUNCT
fnp-4682	12	91	,	,	PUNCT
fnp-4682	12	92	myhc-2x	myhc-2x	PROPN
fnp-4682	12	93	/	/	SYM
fnp-4682	12	94	mhc1	mhc1	PROPN
fnp-4682	12	95	(	(	PUNCT
fnp-4682	12	96	type	type	NOUN
fnp-4682	12	97	2x	2x	NUM
fnp-4682	12	98	fibers	fiber	NOUN
fnp-4682	12	99	)	)	PUNCT
fnp-4682	12	100	and	and	CCONJ
fnp-4682	12	101	myhc-2b	myhc-2b	NOUN
fnp-4682	12	102	/	/	SYM
fnp-4682	12	103	mhc4	mhc4	PROPN
fnp-4682	12	104	(	(	PUNCT
fnp-4682	12	105	type	type	NOUN
fnp-4682	12	106	2b	2b	NUM
fnp-4682	12	107	fibers	fiber	NOUN
fnp-4682	12	108	)	)	PUNCT
fnp-4682	12	109	]	]	PUNCT
fnp-4682	13	1	(	(	PUNCT
fnp-4682	13	2	schiaffino	schiaffino	NOUN
fnp-4682	13	3	et	et	PROPN
fnp-4682	13	4	al	al	PROPN
fnp-4682	13	5	.	.	PROPN
fnp-4682	13	6	,	,	PUNCT
fnp-4682	13	7	2015	2015	NUM
fnp-4682	13	8	)	)	PUNCT
fnp-4682	13	9	.	.	PUNCT
fnp-4682	14	1	during	during	ADP
fnp-4682	14	2	muscle	muscle	NOUN
fnp-4682	14	3	repair	repair	NOUN
fnp-4682	14	4	,	,	PUNCT
fnp-4682	14	5	regenerated	regenerate	VERB
fnp-4682	14	6	myofibers	myofiber	NOUN
fnp-4682	14	7	mature	mature	VERB
fnp-4682	14	8	over	over	ADP
fnp-4682	14	9	~14	~14	NOUN
fnp-4682	14	10	days	day	NOUN
fnp-4682	14	11	by	by	ADP
fnp-4682	14	12	recapitulating	recapitulate	VERB
fnp-4682	14	13	developmental	developmental	ADJ
fnp-4682	14	14	sequence	sequence	NOUN
fnp-4682	14	15	of	of	ADP
fnp-4682	14	16	myhc	myhc	ADJ
fnp-4682	14	17	expression	expression	NOUN
fnp-4682	14	18	:	:	PUNCT
fnp-4682	14	19	newly	newly	ADV
fnp-4682	14	20	formed	form	VERB
fnp-4682	14	21	fibers	fiber	NOUN
fnp-4682	14	22	first	first	ADV
fnp-4682	14	23	express	express	VERB
fnp-4682	14	24	myhc	myhc	PROPN
fnp-4682	14	25	-	-	PUNCT
fnp-4682	14	26	emb	emb	NOUN
fnp-4682	14	27	,	,	PUNCT
fnp-4682	14	28	followed	follow	VERB
fnp-4682	14	29	by	by	ADP
fnp-4682	14	30	myhc	myhc	PROPN
fnp-4682	14	31	-	-	PUNCT
fnp-4682	14	32	neo	neo	PROPN
fnp-4682	14	33	,	,	PUNCT
fnp-4682	14	34	and	and	CCONJ
fnp-4682	14	35	finally	finally	ADV
fnp-4682	14	36	one	one	NUM
fnp-4682	14	37	of	of	ADP
fnp-4682	14	38	the	the	DET
fnp-4682	14	39	adult	adult	NOUN
fnp-4682	14	40	myhc	myhc	NOUN
fnp-4682	14	41	isoforms	isoform	NOUN
fnp-4682	14	42	.	.	PUNCT
fnp-4682	15	1	[	[	X
fnp-4682	15	2	this	this	DET
fnp-4682	15	3	aspect	aspect	NOUN
fnp-4682	15	4	of	of	ADP
fnp-4682	15	5	the	the	DET
fnp-4682	15	6	regeneration	regeneration	NOUN
fnp-4682	15	7	process	process	NOUN
fnp-4682	15	8	is	be	AUX
fnp-4682	15	9	diagnostically	diagnostically	ADV
fnp-4682	15	10	useful	useful	ADJ
fnp-4682	15	11	:	:	PUNCT
fnp-4682	15	12	in	in	ADP
fnp-4682	15	13	adult	adult	NOUN
fnp-4682	15	14	muscle	muscle	NOUN
fnp-4682	15	15	,	,	PUNCT
fnp-4682	15	16	immunohistochemistry	immunohistochemistry	NOUN
fnp-4682	15	17	for	for	ADP
fnp-4682	15	18	developmental	developmental	ADJ
fnp-4682	15	19	myhc	myhc	NOUN
fnp-4682	15	20	isoforms	isoform	NOUN
fnp-4682	15	21	can	can	AUX
fnp-4682	15	22	be	be	AUX
fnp-4682	15	23	used	use	VERB
fnp-4682	15	24	to	to	PART
fnp-4682	15	25	detect	detect	VERB
fnp-4682	15	26	regenerating	regenerate	VERB
fnp-4682	15	27	fibers	fiber	NOUN
fnp-4682	15	28	[	[	X
fnp-4682	15	29	(	(	PUNCT
fnp-4682	15	30	sewry	sewry	PROPN
fnp-4682	15	31	et	et	PROPN
fnp-4682	15	32	al	al	PROPN
fnp-4682	15	33	.	.	PROPN
fnp-4682	15	34	,	,	PUNCT
fnp-4682	15	35	2021	2021	NUM
fnp-4682	15	36	)	)	PUNCT
fnp-4682	15	37	and	and	CCONJ
fnp-4682	15	38	fig	fig	NOUN
fnp-4682	15	39	.	.	PUNCT
fnp-4682	16	1	1	1	NUM
fnp-4682	16	2	.	.	NUM
fnp-4682	16	3	]	]	PUNCT
fnp-4682	16	4	.	.	PUNCT
fnp-4682	17	1	figure	figure	NOUN
fnp-4682	17	2	1	1	NUM
fnp-4682	17	3	.	.	PUNCT
fnp-4682	17	4	regenerating	regenerate	VERB
fnp-4682	17	5	muscle	muscle	NOUN
fnp-4682	17	6	fibers	fiber	NOUN
fnp-4682	17	7	express	express	VERB
fnp-4682	17	8	developmental	developmental	ADJ
fnp-4682	17	9	myosin	myosin	NOUN
fnp-4682	17	10	heavy	heavy	ADJ
fnp-4682	17	11	chain	chain	NOUN
fnp-4682	17	12	isoforms	isoform	NOUN
fnp-4682	17	13	,	,	PUNCT
fnp-4682	17	14	myhc	myhc	PROPN
fnp-4682	17	15	-	-	PUNCT
fnp-4682	17	16	emb	emb	PROPN
fnp-4682	17	17	(	(	PUNCT
fnp-4682	17	18	mhc3	mhc3	PROPN
fnp-4682	17	19	)	)	PUNCT
fnp-4682	17	20	and/or	and/or	CCONJ
fnp-4682	17	21	myhc	myhc	PROPN
fnp-4682	17	22	-	-	PUNCT
fnp-4682	17	23	neo	neo	PROPN
fnp-4682	17	24	(	(	PUNCT
fnp-4682	17	25	mhc8	mhc8	PROPN
fnp-4682	17	26	)	)	PUNCT
fnp-4682	17	27	.	.	PUNCT
fnp-4682	18	1	dual	dual	ADJ
fnp-4682	18	2	immunohistochemical	immunohistochemical	ADJ
fnp-4682	18	3	stain	stain	NOUN
fnp-4682	18	4	for	for	ADP
fnp-4682	18	5	myhc	myhc	PROPN
fnp-4682	18	6	-	-	PUNCT
fnp-4682	18	7	emb	emb	PROPN
fnp-4682	18	8	(	(	PUNCT
fnp-4682	18	9	red	red	ADJ
fnp-4682	18	10	)	)	PUNCT
fnp-4682	18	11	and	and	CCONJ
fnp-4682	18	12	myhc	myhc	PROPN
fnp-4682	18	13	-	-	PUNCT
fnp-4682	18	14	neo	neo	PROPN
fnp-4682	18	15	(	(	PUNCT
fnp-4682	18	16	brown	brown	PROPN
fnp-4682	18	17	)	)	PUNCT
fnp-4682	18	18	,	,	PUNCT
fnp-4682	18	19	here	here	ADV
fnp-4682	18	20	performed	perform	VERB
fnp-4682	18	21	on	on	ADP
fnp-4682	18	22	cryosections	cryosection	NOUN
fnp-4682	18	23	,	,	PUNCT
fnp-4682	18	24	can	can	AUX
fnp-4682	18	25	be	be	AUX
fnp-4682	18	26	used	use	VERB
fnp-4682	18	27	to	to	PART
fnp-4682	18	28	detect	detect	VERB
fnp-4682	18	29	regenerating	regenerate	VERB
fnp-4682	18	30	fibers	fiber	NOUN
fnp-4682	18	31	at	at	ADP
fnp-4682	18	32	different	different	ADJ
fnp-4682	18	33	stages	stage	NOUN
fnp-4682	18	34	of	of	ADP
fnp-4682	18	35	maturation	maturation	NOUN
fnp-4682	18	36	.	.	PUNCT
fnp-4682	19	1	(	(	PUNCT
fnp-4682	19	2	a	a	X
fnp-4682	19	3	)	)	PUNCT
fnp-4682	19	4	in	in	ADP
fnp-4682	19	5	normal	normal	ADJ
fnp-4682	19	6	adult	adult	NOUN
fnp-4682	19	7	skeletal	skeletal	ADJ
fnp-4682	19	8	muscle	muscle	NOUN
fnp-4682	19	9	,	,	PUNCT
fnp-4682	19	10	there	there	PRON
fnp-4682	19	11	is	be	VERB
fnp-4682	19	12	no	no	DET
fnp-4682	19	13	staining	stain	VERB
fnp-4682	19	14	for	for	ADP
fnp-4682	19	15	either	either	PRON
fnp-4682	19	16	myhc	myhc	PROPN
fnp-4682	19	17	-	-	PUNCT
fnp-4682	19	18	emb	emb	PROPN
fnp-4682	19	19	or	or	CCONJ
fnp-4682	19	20	myhc	myhc	PROPN
fnp-4682	19	21	-	-	PUNCT
fnp-4682	19	22	neo	neo	PROPN
fnp-4682	19	23	.	.	PUNCT
fnp-4682	20	1	(	(	PUNCT
fnp-4682	20	2	b	b	X
fnp-4682	20	3	)	)	PUNCT
fnp-4682	20	4	a	a	DET
fnp-4682	20	5	case	case	NOUN
fnp-4682	20	6	of	of	ADP
fnp-4682	20	7	immune	immune	NOUN
fnp-4682	20	8	-	-	PUNCT
fnp-4682	20	9	mediated	mediate	VERB
fnp-4682	20	10	necrotizing	necrotizing	NOUN
fnp-4682	20	11	myopathy	myopathy	NOUN
fnp-4682	20	12	(	(	PUNCT
fnp-4682	20	13	imnm	imnm	PROPN
fnp-4682	20	14	)	)	PUNCT
fnp-4682	20	15	shows	show	VERB
fnp-4682	20	16	frequent	frequent	ADJ
fnp-4682	20	17	regenerating	regenerate	VERB
fnp-4682	20	18	fibers	fiber	NOUN
fnp-4682	20	19	,	,	PUNCT
fnp-4682	20	20	most	most	ADJ
fnp-4682	20	21	of	of	ADP
fnp-4682	20	22	which	which	PRON
fnp-4682	20	23	are	be	AUX
fnp-4682	20	24	in	in	ADP
fnp-4682	20	25	the	the	DET
fnp-4682	20	26	early	early	ADJ
fnp-4682	20	27	stages	stage	NOUN
fnp-4682	20	28	of	of	ADP
fnp-4682	20	29	maturation	maturation	NOUN
fnp-4682	20	30	and	and	CCONJ
fnp-4682	20	31	express	express	VERB
fnp-4682	20	32	only	only	ADV
fnp-4682	20	33	myhc	myhc	PROPN
fnp-4682	20	34	-	-	PUNCT
fnp-4682	20	35	emb	emb	PROPN
fnp-4682	20	36	(	(	PUNCT
fnp-4682	20	37	an	an	DET
fnp-4682	20	38	example	example	NOUN
fnp-4682	20	39	is	be	AUX
fnp-4682	20	40	highlighted	highlight	VERB
fnp-4682	20	41	by	by	ADP
fnp-4682	20	42	the	the	DET
fnp-4682	20	43	green	green	ADJ
fnp-4682	20	44	arrow	arrow	NOUN
fnp-4682	20	45	)	)	PUNCT
fnp-4682	20	46	.	.	PUNCT
fnp-4682	21	1	a	a	DET
fnp-4682	21	2	few	few	ADJ
fnp-4682	21	3	regenerating	regenerate	VERB
fnp-4682	21	4	fibers	fiber	NOUN
fnp-4682	21	5	are	be	AUX
fnp-4682	21	6	in	in	ADP
fnp-4682	21	7	the	the	DET
fnp-4682	21	8	late	late	ADJ
fnp-4682	21	9	stages	stage	NOUN
fnp-4682	21	10	of	of	ADP
fnp-4682	21	11	maturation	maturation	NOUN
fnp-4682	21	12	and	and	CCONJ
fnp-4682	21	13	express	express	VERB
fnp-4682	21	14	only	only	ADV
fnp-4682	21	15	myhc	myhc	PROPN
fnp-4682	21	16	-	-	PUNCT
fnp-4682	21	17	neo	neo	PROPN
fnp-4682	21	18	(	(	PUNCT
fnp-4682	21	19	an	an	DET
fnp-4682	21	20	example	example	NOUN
fnp-4682	21	21	is	be	AUX
fnp-4682	21	22	highlighted	highlight	VERB
fnp-4682	21	23	by	by	ADP
fnp-4682	21	24	the	the	DET
fnp-4682	21	25	orange	orange	PROPN
fnp-4682	21	26	arrow	arrow	NOUN
fnp-4682	21	27	)	)	PUNCT
fnp-4682	21	28	,	,	PUNCT
fnp-4682	21	29	while	while	SCONJ
fnp-4682	21	30	several	several	ADJ
fnp-4682	21	31	regenerating	regenerate	VERB
fnp-4682	21	32	fibers	fiber	NOUN
fnp-4682	21	33	are	be	AUX
fnp-4682	21	34	transitioning	transition	VERB
fnp-4682	21	35	from	from	ADP
fnp-4682	21	36	an	an	DET
fnp-4682	21	37	early	early	ADJ
fnp-4682	21	38	to	to	ADP
fnp-4682	21	39	a	a	DET
fnp-4682	21	40	late	late	ADJ
fnp-4682	21	41	maturation	maturation	NOUN
fnp-4682	21	42	stage	stage	NOUN
fnp-4682	21	43	and	and	CCONJ
fnp-4682	21	44	co	co	NOUN
fnp-4682	21	45	-	-	VERB
fnp-4682	21	46	express	express	ADJ
fnp-4682	21	47	both	both	CCONJ
fnp-4682	21	48	myhc	myhc	PROPN
fnp-4682	21	49	-	-	PUNCT
fnp-4682	21	50	emb	emb	PROPN
fnp-4682	21	51	and	and	CCONJ
fnp-4682	21	52	myhc	myhc	PROPN
fnp-4682	21	53	-	-	PUNCT
fnp-4682	21	54	neo	neo	PROPN
fnp-4682	21	55	(	(	PUNCT
fnp-4682	21	56	dark	dark	ADJ
fnp-4682	21	57	orange	orange	NOUN
fnp-4682	21	58	sarcoplasmic	sarcoplasmic	PROPN
fnp-4682	21	59	staining	staining	NOUN
fnp-4682	21	60	;	;	PUNCT
fnp-4682	21	61	an	an	DET
fnp-4682	21	62	example	example	NOUN
fnp-4682	21	63	is	be	AUX
fnp-4682	21	64	highlighted	highlight	VERB
fnp-4682	21	65	by	by	ADP
fnp-4682	21	66	the	the	DET
fnp-4682	21	67	black	black	ADJ
fnp-4682	21	68	arrow	arrow	NOUN
fnp-4682	21	69	)	)	PUNCT
fnp-4682	21	70	.	.	PUNCT
fnp-4682	22	1	(	(	PUNCT
fnp-4682	22	2	c	c	X
fnp-4682	22	3	)	)	PUNCT
fnp-4682	22	4	a	a	DET
fnp-4682	22	5	case	case	NOUN
fnp-4682	22	6	of	of	ADP
fnp-4682	22	7	sporadic	sporadic	ADJ
fnp-4682	22	8	inclusion	inclusion	NOUN
fnp-4682	22	9	body	body	NOUN
fnp-4682	22	10	myositis	myositis	PROPN
fnp-4682	22	11	(	(	PUNCT
fnp-4682	22	12	sibm	sibm	NOUN
fnp-4682	22	13	)	)	PUNCT
fnp-4682	22	14	shows	show	VERB
fnp-4682	22	15	abundant	abundant	ADJ
fnp-4682	22	16	regenerating	regenerate	VERB
fnp-4682	22	17	fibers	fiber	NOUN
fnp-4682	22	18	spanning	span	VERB
fnp-4682	22	19	the	the	DET
fnp-4682	22	20	entire	entire	ADJ
fnp-4682	22	21	spectrum	spectrum	NOUN
fnp-4682	22	22	of	of	ADP
fnp-4682	22	23	maturation	maturation	NOUN
fnp-4682	22	24	.	.	PUNCT
fnp-4682	23	1	(	(	PUNCT
fnp-4682	23	2	d	d	X
fnp-4682	23	3	)	)	PUNCT
fnp-4682	23	4	in	in	ADP
fnp-4682	23	5	dermatomyositis	dermatomyositis	PROPN
fnp-4682	23	6	(	(	PUNCT
fnp-4682	23	7	dm	dm	PROPN
fnp-4682	23	8	)	)	PUNCT
fnp-4682	23	9	,	,	PUNCT
fnp-4682	23	10	both	both	CCONJ
fnp-4682	23	11	early	early	ADJ
fnp-4682	23	12	and	and	CCONJ
fnp-4682	23	13	late	late	ADJ
fnp-4682	23	14	regenerating	regenerate	VERB
fnp-4682	23	15	fibers	fiber	NOUN
fnp-4682	23	16	are	be	AUX
fnp-4682	23	17	mainly	mainly	ADV
fnp-4682	23	18	found	find	VERB
fnp-4682	23	19	in	in	ADP
fnp-4682	23	20	the	the	DET
fnp-4682	23	21	perifascicular	perifascicular	ADJ
fnp-4682	23	22	areas	area	NOUN
fnp-4682	23	23	.	.	PUNCT
fnp-4682	24	1	scale	scale	NOUN
fnp-4682	24	2	bars	bar	NOUN
fnp-4682	24	3	:	:	PUNCT
fnp-4682	24	4	a	a	PRON
fnp-4682	24	5	and	and	CCONJ
fnp-4682	24	6	d	d	NOUN
fnp-4682	24	7	,	,	PUNCT
fnp-4682	24	8	200	200	NUM
fnp-4682	24	9	µm	µm	NUM
fnp-4682	24	10	;	;	PUNCT
fnp-4682	24	11	b	b	PROPN
fnp-4682	24	12	and	and	CCONJ
fnp-4682	24	13	c	c	NOUN
fnp-4682	24	14	,	,	PUNCT
fnp-4682	24	15	50	50	NUM
fnp-4682	24	16	µm	µm	NOUN
fnp-4682	24	17	.	.	PUNCT
fnp-4682	25	1	wang	wang	PROPN
fnp-4682	25	2	and	and	CCONJ
fnp-4682	25	3	co	co	NOUN
fnp-4682	25	4	-	-	NOUN
fnp-4682	25	5	authors	author	NOUN
fnp-4682	25	6	have	have	AUX
fnp-4682	25	7	now	now	ADV
fnp-4682	25	8	elucidated	elucidate	VERB
fnp-4682	25	9	molecular	molecular	ADJ
fnp-4682	25	10	and	and	CCONJ
fnp-4682	25	11	cellular	cellular	ADJ
fnp-4682	25	12	mechanisms	mechanism	NOUN
fnp-4682	25	13	that	that	PRON
fnp-4682	25	14	regulate	regulate	VERB
fnp-4682	25	15	the	the	DET
fnp-4682	25	16	neonatal	neonatal	ADJ
fnp-4682	25	17	/	/	SYM
fnp-4682	25	18	adult	adult	NOUN
fnp-4682	25	19	transition	transition	NOUN
fnp-4682	25	20	checkpoint	checkpoint	NOUN
fnp-4682	25	21	,	,	PUNCT
fnp-4682	25	22	a	a	DET
fnp-4682	25	23	key	key	ADJ
fnp-4682	25	24	step	step	NOUN
fnp-4682	25	25	in	in	ADP
fnp-4682	25	26	this	this	DET
fnp-4682	25	27	maturation	maturation	NOUN
fnp-4682	25	28	sequence	sequence	NOUN
fnp-4682	25	29	(	(	PUNCT
fnp-4682	25	30	wang	wang	PROPN
fnp-4682	25	31	et	et	PROPN
fnp-4682	25	32	al	al	PROPN
fnp-4682	25	33	.	.	PROPN
fnp-4682	25	34	,	,	PUNCT
fnp-4682	25	35	2022	2022	NUM
fnp-4682	25	36	)	)	PUNCT
fnp-4682	25	37	.	.	PUNCT
fnp-4682	26	1	using	use	VERB
fnp-4682	26	2	a	a	DET
fnp-4682	26	3	myotoxin	myotoxin	ADV
fnp-4682	26	4	-	-	PUNCT
fnp-4682	26	5	induced	induce	VERB
fnp-4682	26	6	model	model	NOUN
fnp-4682	26	7	of	of	ADP
fnp-4682	26	8	skeletal	skeletal	ADJ
fnp-4682	26	9	muscle	muscle	NOUN
fnp-4682	26	10	injury	injury	NOUN
fnp-4682	26	11	,	,	PUNCT
fnp-4682	26	12	they	they	PRON
fnp-4682	26	13	showed	show	VERB
fnp-4682	26	14	that	that	SCONJ
fnp-4682	26	15	expression	expression	NOUN
fnp-4682	26	16	of	of	ADP
fnp-4682	26	17	mitofusin	mitofusin	PROPN
fnp-4682	26	18	2	2	NUM
fnp-4682	26	19	(	(	PUNCT
fnp-4682	26	20	mfn2	mfn2	PROPN
fnp-4682	26	21	;	;	PUNCT
fnp-4682	26	22	a	a	DET
fnp-4682	26	23	mitochondrial	mitochondrial	ADJ
fnp-4682	26	24	membrane	membrane	NOUN
fnp-4682	26	25	protein	protein	NOUN
fnp-4682	26	26	that	that	PRON
fnp-4682	26	27	initiates	initiate	VERB
fnp-4682	26	28	mitochondrial	mitochondrial	ADJ
fnp-4682	26	29	fusion	fusion	NOUN
fnp-4682	26	30	and	and	CCONJ
fnp-4682	26	31	is	be	AUX
fnp-4682	26	32	induced	induce	VERB
fnp-4682	26	33	in	in	ADP
fnp-4682	26	34	activated	activate	VERB
fnp-4682	26	35	satellite	satellite	NOUN
fnp-4682	26	36	cells	cell	NOUN
fnp-4682	26	37	)	)	PUNCT
fnp-4682	26	38	is	be	AUX
fnp-4682	26	39	required	require	VERB
fnp-4682	26	40	for	for	ADP
fnp-4682	26	41	maturation	maturation	NOUN
fnp-4682	26	42	of	of	ADP
fnp-4682	26	43	newly	newly	ADV
fnp-4682	26	44	formed	form	VERB
fnp-4682	26	45	myofibers	myofiber	NOUN
fnp-4682	26	46	:	:	PUNCT
fnp-4682	26	47	in	in	ADP
fnp-4682	26	48	mfn2	mfn2	PROPN
fnp-4682	26	49	-	-	PUNCT
fnp-4682	26	50	deficient	deficient	ADJ
fnp-4682	26	51	mice	mouse	NOUN
fnp-4682	26	52	,	,	PUNCT
fnp-4682	26	53	myotoxic	myotoxic	ADJ
fnp-4682	26	54	muscle	muscle	NOUN
fnp-4682	26	55	injury	injury	NOUN
fnp-4682	26	56	led	lead	VERB
fnp-4682	26	57	to	to	ADP
fnp-4682	26	58	formation	formation	NOUN
fnp-4682	26	59	of	of	ADP
fnp-4682	26	60	early	early	ADJ
fnp-4682	26	61	(	(	PUNCT
fnp-4682	26	62	centrally	centrally	ADV
fnp-4682	26	63	nucleated	nucleated	ADJ
fnp-4682	26	64	,	,	PUNCT
fnp-4682	26	65	mhc3	mhc3	NOUN
fnp-4682	26	66	-	-	PUNCT
fnp-4682	26	67	expressing	express	VERB
fnp-4682	26	68	)	)	PUNCT
fnp-4682	26	69	regenerating	regenerate	VERB
fnp-4682	26	70	fibers	fiber	NOUN
fnp-4682	26	71	,	,	PUNCT
fnp-4682	26	72	but	but	CCONJ
fnp-4682	26	73	these	these	DET
fnp-4682	26	74	fibers	fiber	NOUN
fnp-4682	26	75	were	be	AUX
fnp-4682	26	76	smaller	small	ADJ
fnp-4682	26	77	than	than	ADP
fnp-4682	26	78	regenerating	regenerate	VERB
fnp-4682	26	79	myofibers	myofiber	NOUN
fnp-4682	26	80	in	in	ADP
fnp-4682	26	81	wild	wild	ADJ
fnp-4682	26	82	-	-	PUNCT
fnp-4682	26	83	type	type	NOUN
fnp-4682	26	84	(	(	PUNCT
fnp-4682	26	85	wt	wt	NOUN
fnp-4682	26	86	)	)	PUNCT
fnp-4682	26	87	mice	mouse	NOUN
fnp-4682	26	88	and	and	CCONJ
fnp-4682	26	89	ultimately	ultimately	ADV
fnp-4682	26	90	arrested	arrest	VERB
fnp-4682	26	91	their	their	PRON
fnp-4682	26	92	maturation	maturation	NOUN
fnp-4682	26	93	at	at	ADP
fnp-4682	26	94	the	the	DET
fnp-4682	26	95	neonatal	neonatal	ADJ
fnp-4682	26	96	(	(	PUNCT
fnp-4682	26	97	mhc8	mhc8	NOUN
fnp-4682	26	98	-	-	PUNCT
fnp-4682	26	99	expressing	express	VERB
fnp-4682	26	100	)	)	PUNCT
fnp-4682	26	101	developmental	developmental	ADJ
fnp-4682	26	102	stage	stage	NOUN
fnp-4682	26	103	.	.	PUNCT
fnp-4682	27	1	this	this	DET
fnp-4682	27	2	maturation	maturation	NOUN
fnp-4682	27	3	defect	defect	NOUN
fnp-4682	27	4	was	be	AUX
fnp-4682	27	5	not	not	PART
fnp-4682	27	6	due	due	ADJ
fnp-4682	27	7	to	to	ADP
fnp-4682	27	8	a	a	DET
fnp-4682	27	9	metabolic	metabolic	NOUN
fnp-4682	27	10	abnormality	abnormality	NOUN
fnp-4682	27	11	in	in	ADP
fnp-4682	27	12	satellite	satellite	NOUN
fnp-4682	27	13	cells	cell	NOUN
fnp-4682	27	14	;	;	PUNCT
fnp-4682	27	15	rather	rather	ADV
fnp-4682	27	16	,	,	PUNCT
fnp-4682	27	17	mfn2	mfn2	PROPN
fnp-4682	27	18	deletion	deletion	NOUN
fnp-4682	27	19	led	lead	VERB
fnp-4682	27	20	to	to	ADP
fnp-4682	27	21	nuclear	nuclear	ADJ
fnp-4682	27	22	translocation	translocation	NOUN
fnp-4682	27	23	of	of	ADP
fnp-4682	27	24	transcription	transcription	NOUN
fnp-4682	27	25	factor	factor	NOUN
fnp-4682	27	26	nfatc2	nfatc2	NOUN
fnp-4682	27	27	(	(	PUNCT
fnp-4682	27	28	nuclear	nuclear	ADJ
fnp-4682	27	29	factor	factor	NOUN
fnp-4682	27	30	of	of	ADP
fnp-4682	27	31	activated	activate	VERB
fnp-4682	27	32	t	t	PROPN
fnp-4682	27	33	cells	cell	NOUN
fnp-4682	27	34	2	2	NUM
fnp-4682	27	35	)	)	PUNCT
fnp-4682	27	36	and	and	CCONJ
fnp-4682	27	37	increased	increase	VERB
fnp-4682	27	38	expression	expression	NOUN
fnp-4682	27	39	of	of	ADP
fnp-4682	27	40	hif1α	hif1α	PROPN
fnp-4682	27	41	(	(	PUNCT
fnp-4682	27	42	hypoxia	hypoxia	NOUN
fnp-4682	27	43	-	-	PUNCT
fnp-4682	27	44	induced	induce	VERB
fnp-4682	27	45	factor	factor	NOUN
fnp-4682	27	46	1α	1α	NUM
fnp-4682	27	47	)	)	PUNCT
fnp-4682	27	48	,	,	PUNCT
fnp-4682	27	49	ultimately	ultimately	ADV
fnp-4682	27	50	resulting	result	VERB
fnp-4682	27	51	in	in	ADP
fnp-4682	27	52	the	the	DET
fnp-4682	27	53	lack	lack	NOUN
fnp-4682	27	54	of	of	ADP
fnp-4682	27	55	repressive	repressive	ADJ
fnp-4682	27	56	methylation	methylation	NOUN
fnp-4682	27	57	marks	mark	NOUN
fnp-4682	27	58	at	at	ADP
fnp-4682	27	59	the	the	DET
fnp-4682	27	60	mhc8	mhc8	ADJ
fnp-4682	27	61	genetic	genetic	ADJ
fnp-4682	27	62	locus	locus	NOUN
fnp-4682	27	63	,	,	PUNCT
fnp-4682	27	64	which	which	PRON
fnp-4682	27	65	are	be	AUX
fnp-4682	27	66	required	require	VERB
fnp-4682	27	67	for	for	ADP
fnp-4682	27	68	the	the	DET
fnp-4682	27	69	neonatal	neonatal	ADJ
fnp-4682	27	70	/	/	SYM
fnp-4682	27	71	adult	adult	NOUN
fnp-4682	27	72	fate	fate	NOUN
fnp-4682	27	73	transition	transition	NOUN
fnp-4682	27	74	.	.	PUNCT
fnp-4682	28	1	in	in	ADP
fnp-4682	28	2	wt	wt	PRON
fnp-4682	28	3	animals	animal	NOUN
fnp-4682	28	4	,	,	PUNCT
fnp-4682	28	5	expression	expression	NOUN
fnp-4682	28	6	of	of	ADP
fnp-4682	28	7	hif1α	hif1α	ADJ
fnp-4682	28	8	protein	protein	NOUN
fnp-4682	28	9	was	be	AUX
fnp-4682	28	10	induced	induce	VERB
fnp-4682	28	11	following	follow	VERB
fnp-4682	28	12	muscle	muscle	NOUN
fnp-4682	28	13	injury	injury	NOUN
fnp-4682	28	14	,	,	PUNCT
fnp-4682	28	15	but	but	CCONJ
fnp-4682	28	16	its	its	PRON
fnp-4682	28	17	level	level	NOUN
fnp-4682	28	18	returned	return	VERB
fnp-4682	28	19	to	to	ADP
fnp-4682	28	20	the	the	DET
fnp-4682	28	21	preinjury	preinjury	NOUN
fnp-4682	28	22	baseline	baseline	NOUN
fnp-4682	28	23	within	within	ADP
fnp-4682	28	24	5	5	NUM
fnp-4682	28	25	days	day	NOUN
fnp-4682	28	26	;	;	PUNCT
fnp-4682	28	27	in	in	ADP
fnp-4682	28	28	mfn2	mfn2	PROPN
fnp-4682	28	29	-	-	PUNCT
fnp-4682	28	30	null	null	ADJ
fnp-4682	28	31	animals	animal	NOUN
fnp-4682	28	32	,	,	PUNCT
fnp-4682	28	33	hif1α	hif1α	PROPN
fnp-4682	28	34	levels	level	NOUN
fnp-4682	28	35	remained	remain	VERB
fnp-4682	28	36	elevated	elevated	ADJ
fnp-4682	28	37	14	14	NUM
fnp-4682	28	38	days	day	NOUN
fnp-4682	28	39	post	post	NOUN
fnp-4682	28	40	-	-	NOUN
fnp-4682	28	41	injury	injury	NOUN
fnp-4682	28	42	.	.	PUNCT
fnp-4682	29	1	importantly	importantly	ADV
fnp-4682	29	2	,	,	PUNCT
fnp-4682	29	3	sustained	sustain	VERB
fnp-4682	29	4	hif1α	hif1α	PROPN
fnp-4682	29	5	signaling	signal	VERB
fnp-4682	29	6	was	be	AUX
fnp-4682	29	7	both	both	PRON
fnp-4682	29	8	necessary	necessary	ADJ
fnp-4682	29	9	and	and	CCONJ
fnp-4682	29	10	sufficient	sufficient	ADJ
fnp-4682	29	11	for	for	ADP
fnp-4682	29	12	the	the	DET
fnp-4682	29	13	arrest	arrest	NOUN
fnp-4682	29	14	of	of	ADP
fnp-4682	29	15	regenerating	regenerate	VERB
fnp-4682	29	16	myofibers	myofiber	NOUN
fnp-4682	29	17	at	at	ADP
fnp-4682	29	18	the	the	DET
fnp-4682	29	19	neonatal	neonatal	ADJ
fnp-4682	29	20	stage	stage	NOUN
fnp-4682	29	21	:	:	PUNCT
fnp-4682	29	22	treatment	treatment	NOUN
fnp-4682	29	23	of	of	ADP
fnp-4682	29	24	mfn2-/mice	mfn2-/mice	NOUN
fnp-4682	29	25	with	with	ADP
fnp-4682	29	26	px-478	px-478	PROPN
fnp-4682	29	27	(	(	PUNCT
fnp-4682	29	28	a	a	DET
fnp-4682	29	29	chemical	chemical	NOUN
fnp-4682	29	30	compound	compound	NOUN
fnp-4682	29	31	that	that	PRON
fnp-4682	29	32	reduces	reduce	VERB
fnp-4682	29	33	hif1α	hif1α	PROPN
fnp-4682	29	34	levels	level	NOUN
fnp-4682	29	35	)	)	PUNCT
fnp-4682	29	36	for	for	ADP
fnp-4682	29	37	14	14	NUM
fnp-4682	29	38	days	day	NOUN
fnp-4682	29	39	,	,	PUNCT
fnp-4682	29	40	starting	start	VERB
fnp-4682	29	41	at	at	ADP
fnp-4682	29	42	14	14	NUM
fnp-4682	29	43	days	day	NOUN
fnp-4682	29	44	after	after	ADP
fnp-4682	29	45	muscle	muscle	NOUN
fnp-4682	29	46	injury	injury	PROPN
fnp-4682	29	47	,	,	PUNCT
fnp-4682	29	48	enabled	enable	VERB
fnp-4682	29	49	mfn2-/regenerating	mfn2-/regenerate	VERB
fnp-4682	29	50	myofibers	myofiber	NOUN
fnp-4682	29	51	to	to	PART
fnp-4682	29	52	escape	escape	VERB
fnp-4682	29	53	the	the	DET
fnp-4682	29	54	maturation	maturation	NOUN
fnp-4682	29	55	arrest	arrest	NOUN
fnp-4682	29	56	,	,	PUNCT
fnp-4682	29	57	adopt	adopt	VERB
fnp-4682	29	58	the	the	DET
fnp-4682	29	59	adult	adult	NOUN
fnp-4682	29	60	fate	fate	NOUN
fnp-4682	29	61	,	,	PUNCT
fnp-4682	29	62	and	and	CCONJ
fnp-4682	29	63	grow	grow	VERB
fnp-4682	29	64	closer	close	ADV
fnp-4682	29	65	to	to	ADP
fnp-4682	29	66	a	a	DET
fnp-4682	29	67	normal	normal	ADJ
fnp-4682	29	68	adult	adult	NOUN
fnp-4682	29	69	fiber	fiber	NOUN
fnp-4682	29	70	size	size	NOUN
fnp-4682	29	71	.	.	PUNCT
fnp-4682	30	1	the	the	DET
fnp-4682	30	2	same	same	ADJ
fnp-4682	30	3	rescue	rescue	NOUN
fnp-4682	30	4	could	could	AUX
fnp-4682	30	5	be	be	AUX
fnp-4682	30	6	achieved	achieve	VERB
fnp-4682	30	7	through	through	ADP
fnp-4682	30	8	genetic	genetic	ADJ
fnp-4682	30	9	deletion	deletion	NOUN
fnp-4682	30	10	of	of	ADP
fnp-4682	30	11	hif1α	hif1α	PROPN
fnp-4682	30	12	or	or	CCONJ
fnp-4682	30	13	through	through	ADP
fnp-4682	30	14	inhibition	inhibition	NOUN
fnp-4682	30	15	of	of	ADP
fnp-4682	30	16	h3k27	h3k27	PROPN
fnp-4682	30	17	demethylases	demethylase	NOUN
fnp-4682	30	18	;	;	PUNCT
fnp-4682	30	19	conversely	conversely	ADV
fnp-4682	30	20	,	,	PUNCT
fnp-4682	30	21	the	the	DET
fnp-4682	30	22	effect	effect	NOUN
fnp-4682	30	23	of	of	ADP
fnp-4682	30	24	mfn2	mfn2	NOUN
fnp-4682	30	25	deletion	deletion	NOUN
fnp-4682	30	26	could	could	AUX
fnp-4682	30	27	be	be	AUX
fnp-4682	30	28	replicated	replicate	VERB
fnp-4682	30	29	by	by	ADP
fnp-4682	30	30	genetic	genetic	ADJ
fnp-4682	30	31	manipulation	manipulation	NOUN
fnp-4682	30	32	of	of	ADP
fnp-4682	30	33	vhl	vhl	PROPN
fnp-4682	30	34	(	(	PUNCT
fnp-4682	30	35	von	von	NOUN
fnp-4682	30	36	-	-	PUNCT
fnp-4682	30	37	hippel	hippel	PROPN
fnp-4682	30	38	lindau	lindau	NOUN
fnp-4682	30	39	tumor	tumor	NOUN
fnp-4682	30	40	suppressor	suppressor	NOUN
fnp-4682	30	41	)	)	PUNCT
fnp-4682	30	42	signaling	signaling	NOUN
fnp-4682	30	43	,	,	PUNCT
fnp-4682	30	44	which	which	PRON
fnp-4682	30	45	leads	lead	VERB
fnp-4682	30	46	to	to	ADP
fnp-4682	30	47	hif1α	hif1α	PROPN
fnp-4682	30	48	stabilization	stabilization	NOUN
fnp-4682	30	49	independent	independent	ADJ
fnp-4682	30	50	of	of	ADP
fnp-4682	30	51	mfn2	mfn2	PROPN
fnp-4682	30	52	signaling	signal	VERB
fnp-4682	30	53	.	.	PUNCT
fnp-4682	31	1	finally	finally	ADV
fnp-4682	31	2	,	,	PUNCT
fnp-4682	31	3	the	the	DET
fnp-4682	31	4	authors	author	NOUN
fnp-4682	31	5	used	use	VERB
fnp-4682	31	6	an	an	DET
fnp-4682	31	7	ischemic	ischemic	ADJ
fnp-4682	31	8	model	model	NOUN
fnp-4682	31	9	of	of	ADP
fnp-4682	31	10	muscle	muscle	NOUN
fnp-4682	31	11	injury	injury	NOUN
fnp-4682	31	12	to	to	PART
fnp-4682	31	13	show	show	VERB
fnp-4682	31	14	that	that	SCONJ
fnp-4682	31	15	in	in	ADP
fnp-4682	31	16	wt	wt	ADP
fnp-4682	31	17	mice	mouse	NOUN
fnp-4682	31	18	,	,	PUNCT
fnp-4682	31	19	repressive	repressive	ADJ
fnp-4682	31	20	methylation	methylation	NOUN
fnp-4682	31	21	marks	mark	NOUN
fnp-4682	31	22	at	at	ADP
fnp-4682	31	23	the	the	DET
fnp-4682	31	24	mhc8	mhc8	PROPN
fnp-4682	31	25	locus	locus	NOUN
fnp-4682	31	26	started	start	VERB
fnp-4682	31	27	appearing	appear	VERB
fnp-4682	31	28	on	on	ADP
fnp-4682	31	29	day	day	NOUN
fnp-4682	31	30	9	9	NUM
fnp-4682	31	31	(	(	PUNCT
fnp-4682	31	32	coincidental	coincidental	ADJ
fnp-4682	31	33	with	with	ADP
fnp-4682	31	34	reperfusion	reperfusion	NOUN
fnp-4682	31	35	)	)	PUNCT
fnp-4682	31	36	,	,	PUNCT
fnp-4682	31	37	followed	follow	VERB
fnp-4682	31	38	by	by	ADP
fnp-4682	31	39	fiber	fiber	NOUN
fnp-4682	31	40	growth	growth	NOUN
fnp-4682	31	41	and	and	CCONJ
fnp-4682	31	42	transition	transition	NOUN
fnp-4682	31	43	to	to	ADP
fnp-4682	31	44	the	the	DET
fnp-4682	31	45	adult	adult	NOUN
fnp-4682	31	46	fate	fate	NOUN
fnp-4682	31	47	on	on	ADP
fnp-4682	31	48	day	day	NOUN
fnp-4682	31	49	10	10	NUM
fnp-4682	31	50	,	,	PUNCT
fnp-4682	31	51	and	and	CCONJ
fnp-4682	31	52	complete	complete	ADJ
fnp-4682	31	53	downregulation	downregulation	NOUN
fnp-4682	31	54	of	of	ADP
fnp-4682	31	55	mhc8	mhc8	NOUN
fnp-4682	31	56	expression	expression	NOUN
fnp-4682	31	57	by	by	ADP
fnp-4682	31	58	day	day	NOUN
fnp-4682	31	59	12	12	NUM
fnp-4682	31	60	.	.	PUNCT
fnp-4682	32	1	in	in	ADP
fnp-4682	32	2	contrast	contrast	NOUN
fnp-4682	32	3	,	,	PUNCT
fnp-4682	32	4	myofiber	myofiber	ADJ
fnp-4682	32	5	maturation	maturation	NOUN
fnp-4682	32	6	was	be	AUX
fnp-4682	32	7	significantly	significantly	ADV
fnp-4682	32	8	accelerated	accelerate	VERB
fnp-4682	32	9	in	in	ADP
fnp-4682	32	10	animals	animal	NOUN
fnp-4682	32	11	lacking	lack	VERB
fnp-4682	32	12	hif1α	hif1α	PROPN
fnp-4682	32	13	,	,	PUNCT
fnp-4682	32	14	with	with	ADP
fnp-4682	32	15	completely	completely	ADV
fnp-4682	32	16	differentiated	differentiated	ADJ
fnp-4682	32	17	fibers	fiber	NOUN
fnp-4682	32	18	lacking	lack	VERB
fnp-4682	32	19	any	any	DET
fnp-4682	32	20	mhc8	mhc8	NOUN
fnp-4682	32	21	expression	expression	NOUN
fnp-4682	32	22	present	present	ADJ
fnp-4682	32	23	on	on	ADP
fnp-4682	32	24	day	day	NOUN
fnp-4682	32	25	8	8	NUM
fnp-4682	32	26	.	.	PUNCT
fnp-4682	33	1	taken	take	VERB
fnp-4682	33	2	together	together	ADV
fnp-4682	33	3	,	,	PUNCT
fnp-4682	33	4	these	these	DET
fnp-4682	33	5	data	datum	NOUN
fnp-4682	33	6	indicate	indicate	VERB
fnp-4682	33	7	that	that	SCONJ
fnp-4682	33	8	mfn2	mfn2	PROPN
fnp-4682	33	9	/	/	SYM
fnp-4682	33	10	hif1α	hif1α	PROPN
fnp-4682	33	11	signaling	signal	VERB
fnp-4682	33	12	regulates	regulate	VERB
fnp-4682	33	13	myofiber	myofiber	ADJ
fnp-4682	33	14	fate	fate	NOUN
fnp-4682	33	15	specification	specification	NOUN
fnp-4682	33	16	through	through	ADP
fnp-4682	33	17	the	the	DET
fnp-4682	33	18	epigenetic	epigenetic	ADJ
fnp-4682	33	19	control	control	NOUN
fnp-4682	33	20	of	of	ADP
fnp-4682	33	21	myhc	myhc	PROPN
fnp-4682	33	22	-	-	PUNCT
fnp-4682	33	23	neo	neo	PROPN
fnp-4682	33	24	/	/	SYM
fnp-4682	33	25	mhc8	mhc8	NOUN
fnp-4682	33	26	expression	expression	NOUN
fnp-4682	33	27	,	,	PUNCT
fnp-4682	33	28	and	and	CCONJ
fnp-4682	33	29	that	that	SCONJ
fnp-4682	33	30	this	this	DET
fnp-4682	33	31	checkpoint	checkpoint	NOUN
fnp-4682	33	32	enables	enable	VERB
fnp-4682	33	33	synchronous	synchronous	ADJ
fnp-4682	33	34	development	development	NOUN
fnp-4682	33	35	of	of	ADP
fnp-4682	33	36	all	all	DET
fnp-4682	33	37	skeletal	skeletal	ADJ
fnp-4682	33	38	muscle	muscle	NOUN
fnp-4682	33	39	tissue	tissue	NOUN
fnp-4682	33	40	elements	element	NOUN
fnp-4682	33	41	.	.	PUNCT
fnp-4682	34	1	however	however	ADV
fnp-4682	34	2	,	,	PUNCT
fnp-4682	34	3	it	it	PRON
fnp-4682	34	4	should	should	AUX
fnp-4682	34	5	be	be	AUX
fnp-4682	34	6	noted	note	VERB
fnp-4682	34	7	that	that	SCONJ
fnp-4682	34	8	all	all	DET
fnp-4682	34	9	experiments	experiment	NOUN
fnp-4682	34	10	in	in	ADP
fnp-4682	34	11	this	this	DET
fnp-4682	34	12	study	study	NOUN
fnp-4682	34	13	were	be	AUX
fnp-4682	34	14	done	do	VERB
fnp-4682	34	15	on	on	ADP
fnp-4682	34	16	the	the	DET
fnp-4682	34	17	mouse	mouse	NOUN
fnp-4682	34	18	tibialis	tibialis	PROPN
fnp-4682	34	19	anterior	anterior	ADJ
fnp-4682	34	20	muscle	muscle	NOUN
fnp-4682	34	21	,	,	PUNCT
fnp-4682	34	22	which	which	PRON
fnp-4682	34	23	is	be	AUX
fnp-4682	34	24	largely	largely	ADV
fnp-4682	34	25	composed	compose	VERB
fnp-4682	34	26	of	of	ADP
fnp-4682	34	27	type	type	NOUN
fnp-4682	34	28	2	2	NUM
fnp-4682	34	29	fibers	fiber	NOUN
fnp-4682	34	30	;	;	PUNCT
fnp-4682	34	31	thus	thus	ADV
fnp-4682	34	32	,	,	PUNCT
fnp-4682	34	33	it	it	PRON
fnp-4682	34	34	remains	remain	VERB
fnp-4682	34	35	to	to	PART
fnp-4682	34	36	be	be	AUX
fnp-4682	34	37	shown	show	VERB
fnp-4682	34	38	whether	whether	SCONJ
fnp-4682	34	39	a	a	DET
fnp-4682	34	40	similar	similar	ADJ
fnp-4682	34	41	maturation	maturation	NOUN
fnp-4682	34	42	checkpoint	checkpoint	NOUN
fnp-4682	34	43	also	also	ADV
fnp-4682	34	44	affects	affect	VERB
fnp-4682	34	45	type	type	NOUN
fnp-4682	34	46	1	1	NUM
fnp-4682	34	47	fibers	fiber	NOUN
fnp-4682	34	48	.	.	PUNCT
fnp-4682	35	1	what	what	PRON
fnp-4682	35	2	is	be	AUX
fnp-4682	35	3	the	the	DET
fnp-4682	35	4	relevance	relevance	NOUN
fnp-4682	35	5	of	of	ADP
fnp-4682	35	6	this	this	DET
fnp-4682	35	7	regulatory	regulatory	ADJ
fnp-4682	35	8	pathway	pathway	NOUN
fnp-4682	35	9	for	for	ADP
fnp-4682	35	10	human	human	ADJ
fnp-4682	35	11	disease	disease	NOUN
fnp-4682	35	12	?	?	PUNCT
fnp-4682	36	1	while	while	SCONJ
fnp-4682	36	2	that	that	DET
fnp-4682	36	3	question	question	NOUN
fnp-4682	36	4	needs	need	VERB
fnp-4682	36	5	to	to	PART
fnp-4682	36	6	be	be	AUX
fnp-4682	36	7	investigated	investigate	VERB
fnp-4682	36	8	in	in	ADP
fnp-4682	36	9	much	much	ADV
fnp-4682	36	10	greater	great	ADJ
fnp-4682	36	11	detail	detail	NOUN
fnp-4682	36	12	in	in	ADP
fnp-4682	36	13	the	the	DET
fnp-4682	36	14	future	future	NOUN
fnp-4682	36	15	,	,	PUNCT
fnp-4682	36	16	initial	initial	ADJ
fnp-4682	36	17	experiments	experiment	NOUN
fnp-4682	36	18	performed	perform	VERB
fnp-4682	36	19	by	by	ADP
fnp-4682	36	20	wang	wang	PROPN
fnp-4682	36	21	and	and	CCONJ
fnp-4682	36	22	co	co	NOUN
fnp-4682	36	23	-	-	NOUN
fnp-4682	36	24	authors	author	NOUN
fnp-4682	36	25	offer	offer	VERB
fnp-4682	36	26	some	some	DET
fnp-4682	36	27	tantalizing	tantalizing	ADJ
fnp-4682	36	28	clues	clue	NOUN
fnp-4682	36	29	.	.	PUNCT
fnp-4682	37	1	because	because	SCONJ
fnp-4682	37	2	maturation	maturation	NOUN
fnp-4682	37	3	-	-	PUNCT
fnp-4682	37	4	arrested	arrest	VERB
fnp-4682	37	5	regenerating	regenerate	VERB
fnp-4682	37	6	fibers	fiber	NOUN
fnp-4682	37	7	are	be	AUX
fnp-4682	37	8	reminiscent	reminiscent	ADJ
fnp-4682	37	9	of	of	ADP
fnp-4682	37	10	atrophic	atrophic	ADJ
fnp-4682	37	11	,	,	PUNCT
fnp-4682	37	12	centrally	centrally	ADV
fnp-4682	37	13	nucleated	nucleated	ADJ
fnp-4682	37	14	fibers	fiber	NOUN
fnp-4682	37	15	seen	see	VERB
fnp-4682	37	16	in	in	ADP
fnp-4682	37	17	severe	severe	ADJ
fnp-4682	37	18	centronuclear	centronuclear	ADJ
fnp-4682	37	19	myopathies	myopathy	NOUN
fnp-4682	37	20	(	(	PUNCT
fnp-4682	37	21	cnms	cnms	NOUN
fnp-4682	37	22	)	)	PUNCT
fnp-4682	37	23	,	,	PUNCT
fnp-4682	37	24	they	they	PRON
fnp-4682	37	25	evaluated	evaluate	VERB
fnp-4682	37	26	biopsies	biopsy	NOUN
fnp-4682	37	27	from	from	ADP
fnp-4682	37	28	infantile	infantile	ADJ
fnp-4682	37	29	patients	patient	NOUN
fnp-4682	37	30	with	with	ADP
fnp-4682	37	31	cnm	cnm	PROPN
fnp-4682	37	32	1	1	NUM
fnp-4682	37	33	(	(	PUNCT
fnp-4682	37	34	caused	cause	VERB
fnp-4682	37	35	by	by	ADP
fnp-4682	37	36	mutations	mutation	NOUN
fnp-4682	37	37	in	in	ADP
fnp-4682	37	38	dynamin	dynamin	NOUN
fnp-4682	37	39	2	2	NUM
fnp-4682	37	40	)	)	PUNCT
fnp-4682	37	41	and	and	CCONJ
fnp-4682	37	42	cnm	cnm	X
fnp-4682	37	43	2	2	NUM
fnp-4682	37	44	/	/	SYM
fnp-4682	37	45	x	x	NOUN
fnp-4682	37	46	-	-	VERB
fnp-4682	37	47	linked	link	VERB
fnp-4682	37	48	myotubular	myotubular	ADJ
fnp-4682	37	49	myopathy	myopathy	NOUN
fnp-4682	37	50	(	(	PUNCT
fnp-4682	37	51	xlmtm	xlmtm	PROPN
fnp-4682	37	52	,	,	PUNCT
fnp-4682	37	53	caused	cause	VERB
fnp-4682	37	54	by	by	ADP
fnp-4682	37	55	mutations	mutation	NOUN
fnp-4682	37	56	in	in	ADP
fnp-4682	37	57	myotubularin	myotubularin	NOUN
fnp-4682	37	58	1	1	NUM
fnp-4682	37	59	)	)	PUNCT
fnp-4682	37	60	;	;	PUNCT
fnp-4682	37	61	in	in	ADP
fnp-4682	37	62	both	both	DET
fnp-4682	37	63	diseases	disease	NOUN
fnp-4682	37	64	,	,	PUNCT
fnp-4682	37	65	they	they	PRON
fnp-4682	37	66	detected	detect	VERB
fnp-4682	37	67	myofibers	myofiber	NOUN
fnp-4682	37	68	strongly	strongly	ADV
fnp-4682	37	69	positive	positive	ADJ
fnp-4682	37	70	for	for	ADP
fnp-4682	37	71	mhc8	mhc8	NOUN
fnp-4682	37	72	as	as	ADV
fnp-4682	37	73	well	well	ADV
fnp-4682	37	74	as	as	ADP
fnp-4682	37	75	nuclear	nuclear	ADJ
fnp-4682	37	76	nfatc2	nfatc2	NOUN
fnp-4682	37	77	and	and	CCONJ
fnp-4682	37	78	sarcoplasmic	sarcoplasmic	ADJ
fnp-4682	37	79	carbonic	carbonic	NOUN
fnp-4682	37	80	anhydrase	anhydrase	NOUN
fnp-4682	37	81	3	3	NUM
fnp-4682	37	82	(	(	PUNCT
fnp-4682	37	83	a	a	DET
fnp-4682	37	84	hif1α	hif1α	ADJ
fnp-4682	37	85	target	target	NOUN
fnp-4682	37	86	)	)	PUNCT
fnp-4682	37	87	.	.	PUNCT
fnp-4682	38	1	while	while	SCONJ
fnp-4682	38	2	mhc3	mhc3	PROPN
fnp-4682	38	3	+	+	NOUN
fnp-4682	38	4	and	and	CCONJ
fnp-4682	38	5	mhc8	mhc8	NOUN
fnp-4682	38	6	+	+	CCONJ
fnp-4682	38	7	positive	positive	ADJ
fnp-4682	38	8	fibers	fiber	NOUN
fnp-4682	38	9	can	can	AUX
fnp-4682	38	10	be	be	AUX
fnp-4682	38	11	seen	see	VERB
fnp-4682	38	12	in	in	ADP
fnp-4682	38	13	any	any	DET
fnp-4682	38	14	myopathy	myopathy	NOUN
fnp-4682	38	15	that	that	PRON
fnp-4682	38	16	involves	involve	VERB
fnp-4682	38	17	significant	significant	ADJ
fnp-4682	38	18	fiber	fiber	NOUN
fnp-4682	38	19	necrosis	necrosis	NOUN
fnp-4682	38	20	(	(	PUNCT
fnp-4682	38	21	fig	fig	NOUN
fnp-4682	38	22	.	.	NOUN
fnp-4682	39	1	1	1	NUM
fnp-4682	39	2	)	)	PUNCT
fnp-4682	39	3	,	,	PUNCT
fnp-4682	39	4	they	they	PRON
fnp-4682	39	5	are	be	AUX
fnp-4682	39	6	generally	generally	ADV
fnp-4682	39	7	not	not	PART
fnp-4682	39	8	very	very	ADV
fnp-4682	39	9	numerous	numerous	ADJ
fnp-4682	39	10	in	in	ADP
fnp-4682	39	11	congenital	congenital	ADJ
fnp-4682	39	12	myopathies	myopathy	NOUN
fnp-4682	39	13	,	,	PUNCT
fnp-4682	39	14	raising	raise	VERB
fnp-4682	39	15	the	the	DET
fnp-4682	39	16	possibility	possibility	NOUN
fnp-4682	39	17	that	that	SCONJ
fnp-4682	39	18	the	the	DET
fnp-4682	39	19	mfn2	mfn2	PROPN
fnp-4682	39	20	/	/	SYM
fnp-4682	39	21	hif1α	hif1α	PROPN
fnp-4682	39	22	-	-	PUNCT
fnp-4682	39	23	controlled	control	VERB
fnp-4682	39	24	maturation	maturation	NOUN
fnp-4682	39	25	checkpoint	checkpoint	NOUN
fnp-4682	39	26	is	be	AUX
fnp-4682	39	27	specifically	specifically	ADV
fnp-4682	39	28	dysregulated	dysregulate	VERB
fnp-4682	39	29	in	in	ADP
fnp-4682	39	30	cnms	cnms	NOUN
fnp-4682	39	31	.	.	PUNCT
fnp-4682	40	1	interestingly	interestingly	ADV
fnp-4682	40	2	,	,	PUNCT
fnp-4682	40	3	a	a	DET
fnp-4682	40	4	different	different	ADJ
fnp-4682	40	5	2022	2022	NUM
fnp-4682	40	6	study	study	NOUN
fnp-4682	40	7	demonstrated	demonstrate	VERB
fnp-4682	40	8	that	that	SCONJ
fnp-4682	40	9	epigenetic	epigenetic	ADJ
fnp-4682	40	10	alterations	alteration	NOUN
fnp-4682	40	11	are	be	AUX
fnp-4682	40	12	a	a	DET
fnp-4682	40	13	conserved	conserved	ADJ
fnp-4682	40	14	feature	feature	NOUN
fnp-4682	40	15	of	of	ADP
fnp-4682	40	16	xlmtm	xlmtm	PROPN
fnp-4682	40	17	and	and	CCONJ
fnp-4682	40	18	that	that	SCONJ
fnp-4682	40	19	histone	histone	NOUN
fnp-4682	40	20	deacetylase	deacetylase	NOUN
fnp-4682	40	21	inhibition	inhibition	NOUN
fnp-4682	40	22	is	be	AUX
fnp-4682	40	23	a	a	DET
fnp-4682	40	24	promising	promising	ADJ
fnp-4682	40	25	therapeutic	therapeutic	ADJ
fnp-4682	40	26	strategy	strategy	NOUN
fnp-4682	40	27	for	for	ADP
fnp-4682	40	28	this	this	DET
fnp-4682	40	29	severe	severe	ADJ
fnp-4682	40	30	muscle	muscle	NOUN
fnp-4682	40	31	disease	disease	NOUN
fnp-4682	40	32	(	(	PUNCT
fnp-4682	40	33	volpatti	volpatti	NOUN
fnp-4682	40	34	et	et	PROPN
fnp-4682	40	35	al	al	PROPN
fnp-4682	40	36	.	.	PROPN
fnp-4682	40	37	,	,	PUNCT
fnp-4682	40	38	2022	2022	NUM
fnp-4682	40	39	)	)	PUNCT
fnp-4682	40	40	.	.	PUNCT
fnp-4682	41	1	while	while	SCONJ
fnp-4682	41	2	altered	alter	VERB
fnp-4682	41	3	muscle	muscle	NOUN
fnp-4682	41	4	development	development	NOUN
fnp-4682	41	5	is	be	AUX
fnp-4682	41	6	one	one	NUM
fnp-4682	41	7	of	of	ADP
fnp-4682	41	8	the	the	DET
fnp-4682	41	9	epigenetically	epigenetically	ADV
fnp-4682	41	10	modified	modify	VERB
fnp-4682	41	11	pathways	pathway	NOUN
fnp-4682	41	12	uncovered	uncover	VERB
fnp-4682	41	13	by	by	ADP
fnp-4682	41	14	volpatti	volpatti	PROPN
fnp-4682	41	15	et	et	PROPN
fnp-4682	41	16	al	al	PROPN
fnp-4682	41	17	.	.	PROPN
fnp-4682	41	18	,	,	PUNCT
fnp-4682	41	19	it	it	PRON
fnp-4682	41	20	remains	remain	VERB
fnp-4682	41	21	to	to	PART
fnp-4682	41	22	be	be	AUX
fnp-4682	41	23	shown	show	VERB
fnp-4682	41	24	whether	whether	SCONJ
fnp-4682	41	25	changes	change	NOUN
fnp-4682	41	26	in	in	ADP
fnp-4682	41	27	the	the	DET
fnp-4682	41	28	methylation	methylation	NOUN
fnp-4682	41	29	of	of	ADP
fnp-4682	41	30	the	the	DET
fnp-4682	41	31	mhc8	mhc8	PROPN
fnp-4682	41	32	genetic	genetic	ADJ
fnp-4682	41	33	locus	locus	NOUN
fnp-4682	41	34	are	be	AUX
fnp-4682	41	35	part	part	NOUN
fnp-4682	41	36	of	of	ADP
fnp-4682	41	37	the	the	DET
fnp-4682	41	38	xlmtm	xlmtm	ADJ
fnp-4682	41	39	epigenetic	epigenetic	ADJ
fnp-4682	41	40	disease	disease	NOUN
fnp-4682	41	41	signature	signature	NOUN
fnp-4682	41	42	.	.	PUNCT
fnp-4682	42	1	interestingly	interestingly	ADV
fnp-4682	42	2	,	,	PUNCT
fnp-4682	42	3	autosomal	autosomal	ADJ
fnp-4682	42	4	dominant	dominant	ADJ
fnp-4682	42	5	mutations	mutation	NOUN
fnp-4682	42	6	in	in	ADP
fnp-4682	42	7	mfn2	mfn2	PROPN
fnp-4682	42	8	cause	cause	VERB
fnp-4682	42	9	axonal	axonal	ADJ
fnp-4682	42	10	charcot	charcot	PROPN
fnp-4682	42	11	-	-	PUNCT
fnp-4682	42	12	marie	marie	PROPN
fnp-4682	42	13	-	-	PUNCT
fnp-4682	42	14	tooth	tooth	NOUN
fnp-4682	42	15	disease	disease	NOUN
fnp-4682	42	16	type	type	NOUN
fnp-4682	42	17	2a	2a	NUM
fnp-4682	42	18	(	(	PUNCT
fnp-4682	42	19	cmt	cmt	PROPN
fnp-4682	42	20	2a	2a	NUM
fnp-4682	42	21	)	)	PUNCT
fnp-4682	42	22	but	but	CCONJ
fnp-4682	42	23	are	be	AUX
fnp-4682	42	24	not	not	PART
fnp-4682	42	25	known	know	VERB
fnp-4682	42	26	to	to	PART
fnp-4682	42	27	produce	produce	VERB
fnp-4682	42	28	a	a	DET
fnp-4682	42	29	significant	significant	ADJ
fnp-4682	42	30	myopathic	myopathic	ADJ
fnp-4682	42	31	phenotype	phenotype	NOUN
fnp-4682	42	32	.	.	PUNCT
fnp-4682	43	1	it	it	PRON
fnp-4682	43	2	is	be	AUX
fnp-4682	43	3	possible	possible	ADJ
fnp-4682	43	4	that	that	SCONJ
fnp-4682	43	5	cmt	cmt	PROPN
fnp-4682	43	6	2a	2a	PROPN
fnp-4682	43	7	patients	patient	NOUN
fnp-4682	43	8	exhibit	exhibit	VERB
fnp-4682	43	9	atypical	atypical	ADJ
fnp-4682	43	10	muscle	muscle	NOUN
fnp-4682	43	11	development	development	NOUN
fnp-4682	43	12	and/or	and/or	CCONJ
fnp-4682	43	13	aberrant	aberrant	ADJ
fnp-4682	43	14	response	response	NOUN
fnp-4682	43	15	to	to	ADP
fnp-4682	43	16	muscle	muscle	NOUN
fnp-4682	43	17	injury	injury	NOUN
fnp-4682	43	18	that	that	PRON
fnp-4682	43	19	contributes	contribute	VERB
fnp-4682	43	20	to	to	ADP
fnp-4682	43	21	their	their	PRON
fnp-4682	43	22	weakness	weakness	NOUN
fnp-4682	43	23	but	but	CCONJ
fnp-4682	43	24	has	have	AUX
fnp-4682	43	25	been	be	AUX
fnp-4682	43	26	masked	mask	VERB
fnp-4682	43	27	by	by	ADP
fnp-4682	43	28	their	their	PRON
fnp-4682	43	29	peripheral	peripheral	ADJ
fnp-4682	43	30	neuropathy	neuropathy	ADJ
fnp-4682	43	31	;	;	PUNCT
fnp-4682	43	32	that	that	PRON
fnp-4682	43	33	needs	need	VERB
fnp-4682	43	34	to	to	PART
fnp-4682	43	35	be	be	AUX
fnp-4682	43	36	explored	explore	VERB
fnp-4682	43	37	by	by	ADP
fnp-4682	43	38	future	future	ADJ
fnp-4682	43	39	studies	study	NOUN
fnp-4682	43	40	.	.	PUNCT
fnp-4682	44	1	in	in	ADP
fnp-4682	44	2	addition	addition	NOUN
fnp-4682	44	3	,	,	PUNCT
fnp-4682	44	4	it	it	PRON
fnp-4682	44	5	needs	need	VERB
fnp-4682	44	6	to	to	PART
fnp-4682	44	7	be	be	AUX
fnp-4682	44	8	investigated	investigate	VERB
fnp-4682	44	9	whether	whether	SCONJ
fnp-4682	44	10	pharmaceutical	pharmaceutical	ADJ
fnp-4682	44	11	treatments	treatment	NOUN
fnp-4682	44	12	that	that	PRON
fnp-4682	44	13	turn	turn	VERB
fnp-4682	44	14	off	off	ADP
fnp-4682	44	15	this	this	DET
fnp-4682	44	16	maturation	maturation	NOUN
fnp-4682	44	17	checkpoint	checkpoint	NOUN
fnp-4682	44	18	can	can	AUX
fnp-4682	44	19	accelerate	accelerate	VERB
fnp-4682	44	20	muscle	muscle	NOUN
fnp-4682	44	21	repair	repair	NOUN
fnp-4682	44	22	following	follow	VERB
fnp-4682	44	23	injury	injury	NOUN
fnp-4682	44	24	and/or	and/or	CCONJ
fnp-4682	44	25	prove	prove	VERB
fnp-4682	44	26	beneficial	beneficial	ADJ
fnp-4682	44	27	for	for	ADP
fnp-4682	44	28	any	any	DET
fnp-4682	44	29	muscle	muscle	NOUN
fnp-4682	44	30	disease	disease	NOUN
fnp-4682	44	31	characterized	characterize	VERB
fnp-4682	44	32	by	by	ADP
fnp-4682	44	33	significant	significant	ADJ
fnp-4682	44	34	fiber	fiber	NOUN
fnp-4682	44	35	necrosis	necrosis	NOUN
fnp-4682	44	36	and	and	CCONJ
fnp-4682	44	37	regeneration	regeneration	NOUN
fnp-4682	44	38	.	.	PUNCT
fnp-4682	45	1	newly	newly	ADV
fnp-4682	45	2	defined	define	VERB
fnp-4682	45	3	/	/	SYM
fnp-4682	45	4	emerging	emerge	VERB
fnp-4682	45	5	neuromuscular	neuromuscular	ADJ
fnp-4682	45	6	diseases	disease	NOUN
fnp-4682	45	7	2	2	NUM
fnp-4682	45	8	.	.	X
fnp-4682	45	9	neuromuscular	neuromuscular	ADJ
fnp-4682	45	10	complications	complication	NOUN
fnp-4682	45	11	of	of	ADP
fnp-4682	45	12	covid-19	covid-19	PROPN
fnp-4682	45	13	:	:	PUNCT
fnp-4682	45	14	post	post	ADJ
fnp-4682	45	15	-	-	ADJ
fnp-4682	45	16	acute	acute	ADJ
fnp-4682	45	17	sequelae	sequelae	NOUN
fnp-4682	45	18	of	of	ADP
fnp-4682	45	19	sars	sar	NOUN
fnp-4682	45	20	-	-	PUNCT
fnp-4682	45	21	cov-2	cov-2	PART
fnp-4682	45	22	infection	infection	NOUN
fnp-4682	45	23	(	(	PUNCT
fnp-4682	45	24	“	"	PUNCT
fnp-4682	45	25	long	long	ADJ
fnp-4682	45	26	covid	covid	NOUN
fnp-4682	45	27	”	"	PUNCT
fnp-4682	45	28	)	)	PUNCT
fnp-4682	45	29	syndrome	syndrome	NOUN
fnp-4682	45	30	covid-19	covid-19	PROPN
fnp-4682	45	31	,	,	PUNCT
fnp-4682	45	32	the	the	DET
fnp-4682	45	33	novel	novel	ADJ
fnp-4682	45	34	infectious	infectious	ADJ
fnp-4682	45	35	disease	disease	NOUN
fnp-4682	45	36	caused	cause	VERB
fnp-4682	45	37	by	by	ADP
fnp-4682	45	38	sars	sar	NOUN
fnp-4682	45	39	-	-	PUNCT
fnp-4682	45	40	cov-2	cov-2	NOUN
fnp-4682	45	41	,	,	PUNCT
fnp-4682	45	42	primarily	primarily	ADV
fnp-4682	45	43	targets	target	VERB
fnp-4682	45	44	the	the	DET
fnp-4682	45	45	respiratory	respiratory	ADJ
fnp-4682	45	46	system	system	NOUN
fnp-4682	45	47	but	but	CCONJ
fnp-4682	45	48	also	also	ADV
fnp-4682	45	49	affects	affect	VERB
fnp-4682	45	50	many	many	ADJ
fnp-4682	45	51	other	other	ADJ
fnp-4682	45	52	tissues	tissue	NOUN
fnp-4682	45	53	and	and	CCONJ
fnp-4682	45	54	organs	organ	NOUN
fnp-4682	45	55	,	,	PUNCT
fnp-4682	45	56	including	include	VERB
fnp-4682	45	57	the	the	DET
fnp-4682	45	58	pns	pns	NOUN
fnp-4682	45	59	.	.	PUNCT
fnp-4682	46	1	in	in	ADP
fnp-4682	46	2	the	the	DET
fnp-4682	46	3	past	past	ADJ
fnp-4682	46	4	two	two	NUM
fnp-4682	46	5	reviews	review	NOUN
fnp-4682	46	6	(	(	PUNCT
fnp-4682	46	7	margeta	margeta	NOUN
fnp-4682	46	8	,	,	PUNCT
fnp-4682	46	9	2021	2021	NUM
fnp-4682	46	10	,	,	PUNCT
fnp-4682	46	11	2022	2022	NUM
fnp-4682	46	12	)	)	PUNCT
fnp-4682	46	13	,	,	PUNCT
fnp-4682	46	14	i	i	PRON
fnp-4682	46	15	discussed	discuss	VERB
fnp-4682	46	16	the	the	DET
fnp-4682	46	17	emerging	emerge	VERB
fnp-4682	46	18	understanding	understanding	NOUN
fnp-4682	46	19	of	of	ADP
fnp-4682	46	20	acute	acute	ADJ
fnp-4682	46	21	neuromuscular	neuromuscular	ADJ
fnp-4682	46	22	complications	complication	NOUN
fnp-4682	46	23	of	of	ADP
fnp-4682	46	24	covid-19	covid-19	PROPN
fnp-4682	46	25	;	;	PUNCT
fnp-4682	46	26	in	in	ADP
fnp-4682	46	27	this	this	DET
fnp-4682	46	28	review	review	NOUN
fnp-4682	46	29	,	,	PUNCT
fnp-4682	46	30	i	i	PRON
fnp-4682	46	31	will	will	AUX
fnp-4682	46	32	summarize	summarize	VERB
fnp-4682	46	33	what	what	PRON
fnp-4682	46	34	is	be	AUX
fnp-4682	46	35	currently	currently	ADV
fnp-4682	46	36	known	know	VERB
fnp-4682	46	37	about	about	ADP
fnp-4682	46	38	neuromuscular	neuromuscular	ADJ
fnp-4682	46	39	involvement	involvement	NOUN
fnp-4682	46	40	in	in	ADP
fnp-4682	46	41	the	the	DET
fnp-4682	46	42	post	post	ADJ
fnp-4682	46	43	-	-	ADJ
fnp-4682	46	44	acute	acute	ADJ
fnp-4682	46	45	sequelae	sequelae	NOUN
fnp-4682	46	46	of	of	ADP
fnp-4682	46	47	sars	sar	NOUN
fnp-4682	46	48	-	-	PUNCT
fnp-4682	46	49	cov-2	cov-2	PART
fnp-4682	46	50	infection	infection	NOUN
fnp-4682	46	51	(	(	PUNCT
fnp-4682	46	52	pasc	pasc	PROPN
fnp-4682	46	53	)	)	PUNCT
fnp-4682	46	54	syndrome	syndrome	NOUN
fnp-4682	46	55	(	(	PUNCT
fnp-4682	46	56	also	also	ADV
fnp-4682	46	57	known	know	VERB
fnp-4682	46	58	as	as	ADP
fnp-4682	46	59	“	"	PUNCT
fnp-4682	46	60	post	post	ADJ
fnp-4682	46	61	-	-	ADJ
fnp-4682	46	62	covid	covid	ADJ
fnp-4682	46	63	conditions	condition	NOUN
fnp-4682	46	64	”	"	PUNCT
fnp-4682	46	65	or	or	CCONJ
fnp-4682	46	66	“	"	PUNCT
fnp-4682	46	67	long	long	ADJ
fnp-4682	46	68	covid	covid	NOUN
fnp-4682	46	69	”	"	PUNCT
fnp-4682	46	70	)	)	PUNCT
fnp-4682	46	71	.	.	PUNCT
fnp-4682	47	1	the	the	DET
fnp-4682	47	2	cdc	cdc	PROPN
fnp-4682	47	3	(	(	PUNCT
fnp-4682	47	4	centers	center	NOUN
fnp-4682	47	5	for	for	ADP
fnp-4682	47	6	disease	disease	NOUN
fnp-4682	47	7	control	control	NOUN
fnp-4682	47	8	and	and	CCONJ
fnp-4682	47	9	prevention	prevention	NOUN
fnp-4682	47	10	,	,	PUNCT
fnp-4682	47	11	a	a	DET
fnp-4682	47	12	branch	branch	NOUN
fnp-4682	47	13	of	of	ADP
fnp-4682	47	14	the	the	DET
fnp-4682	47	15	united	united	PROPN
fnp-4682	47	16	states	states	PROPN
fnp-4682	47	17	government	government	NOUN
fnp-4682	47	18	)	)	PUNCT
fnp-4682	47	19	defines	define	VERB
fnp-4682	47	20	pasc	pasc	X
fnp-4682	47	21	as	as	ADP
fnp-4682	47	22	continuation	continuation	NOUN
fnp-4682	47	23	of	of	ADP
fnp-4682	47	24	covid-19	covid-19	PROPN
fnp-4682	47	25	symptoms	symptom	NOUN
fnp-4682	47	26	–	–	PUNCT
fnp-4682	47	27	or	or	CCONJ
fnp-4682	47	28	the	the	DET
fnp-4682	47	29	emergence	emergence	NOUN
fnp-4682	47	30	of	of	ADP
fnp-4682	47	31	new	new	ADJ
fnp-4682	47	32	symptoms	symptom	NOUN
fnp-4682	47	33	–	–	PUNCT
fnp-4682	47	34	four	four	NUM
fnp-4682	47	35	weeks	week	NOUN
fnp-4682	47	36	or	or	CCONJ
fnp-4682	47	37	longer	long	ADV
fnp-4682	47	38	after	after	ADP
fnp-4682	47	39	initial	initial	ADJ
fnp-4682	47	40	sars	sar	NOUN
fnp-4682	47	41	-	-	PUNCT
fnp-4682	47	42	cov-2	cov-2	PART
fnp-4682	47	43	infection	infection	NOUN
fnp-4682	47	44	;	;	PUNCT
fnp-4682	47	45	given	give	VERB
fnp-4682	47	46	this	this	DET
fnp-4682	47	47	broad	broad	ADJ
fnp-4682	47	48	definition	definition	NOUN
fnp-4682	47	49	and	and	CCONJ
fnp-4682	47	50	the	the	DET
fnp-4682	47	51	continuously	continuously	ADV
fnp-4682	47	52	changing	change	VERB
fnp-4682	47	53	spectrum	spectrum	NOUN
fnp-4682	47	54	of	of	ADP
fnp-4682	47	55	viral	viral	ADJ
fnp-4682	47	56	variants	variant	NOUN
fnp-4682	47	57	,	,	PUNCT
fnp-4682	47	58	the	the	DET
fnp-4682	47	59	true	true	ADJ
fnp-4682	47	60	prevalence	prevalence	NOUN
fnp-4682	47	61	of	of	ADP
fnp-4682	47	62	pasc	pasc	PROPN
fnp-4682	47	63	is	be	AUX
fnp-4682	47	64	not	not	PART
fnp-4682	47	65	known	know	VERB
fnp-4682	47	66	,	,	PUNCT
fnp-4682	47	67	but	but	CCONJ
fnp-4682	47	68	the	the	DET
fnp-4682	47	69	current	current	ADJ
fnp-4682	47	70	estimates	estimate	NOUN
fnp-4682	47	71	range	range	VERB
fnp-4682	47	72	from	from	ADP
fnp-4682	47	73	5	5	NUM
fnp-4682	47	74	-	-	SYM
fnp-4682	47	75	30	30	NUM
fnp-4682	47	76	%	%	NOUN
fnp-4682	47	77	.	.	PUNCT
fnp-4682	48	1	while	while	SCONJ
fnp-4682	48	2	pasc	pasc	PROPN
fnp-4682	48	3	can	can	AUX
fnp-4682	48	4	include	include	VERB
fnp-4682	48	5	a	a	DET
fnp-4682	48	6	wide	wide	ADJ
fnp-4682	48	7	array	array	NOUN
fnp-4682	48	8	of	of	ADP
fnp-4682	48	9	symptoms	symptom	NOUN
fnp-4682	48	10	,	,	PUNCT
fnp-4682	48	11	some	some	PRON
fnp-4682	48	12	of	of	ADP
fnp-4682	48	13	the	the	DET
fnp-4682	48	14	most	most	ADV
fnp-4682	48	15	common	common	ADJ
fnp-4682	48	16	and	and	CCONJ
fnp-4682	48	17	particularly	particularly	ADV
fnp-4682	48	18	debilitating	debilitate	VERB
fnp-4682	48	19	concerns	concern	NOUN
fnp-4682	48	20	(	(	PUNCT
fnp-4682	48	21	including	include	VERB
fnp-4682	48	22	fatigue	fatigue	NOUN
fnp-4682	48	23	/	/	SYM
fnp-4682	48	24	exertional	exertional	ADJ
fnp-4682	48	25	intolerance	intolerance	NOUN
fnp-4682	48	26	,	,	PUNCT
fnp-4682	48	27	dysautonomia	dysautonomia	NOUN
fnp-4682	48	28	,	,	PUNCT
fnp-4682	48	29	and	and	CCONJ
fnp-4682	48	30	sensory	sensory	ADJ
fnp-4682	48	31	symptoms	symptom	NOUN
fnp-4682	48	32	such	such	ADJ
fnp-4682	48	33	as	as	ADP
fnp-4682	48	34	paresthesias	paresthesia	NOUN
fnp-4682	48	35	and	and	CCONJ
fnp-4682	48	36	numbness	numbness	NOUN
fnp-4682	48	37	)	)	PUNCT
fnp-4682	48	38	suggest	suggest	VERB
fnp-4682	48	39	that	that	SCONJ
fnp-4682	48	40	the	the	DET
fnp-4682	48	41	pns	pns	NOUN
fnp-4682	48	42	is	be	AUX
fnp-4682	48	43	affected	affect	VERB
fnp-4682	48	44	.	.	PUNCT
fnp-4682	49	1	two	two	NUM
fnp-4682	49	2	small	small	ADJ
fnp-4682	49	3	retrospective	retrospective	ADJ
fnp-4682	49	4	studies	study	NOUN
fnp-4682	49	5	published	publish	VERB
fnp-4682	49	6	in	in	ADP
fnp-4682	49	7	2022	2022	NUM
fnp-4682	49	8	explored	explore	VERB
fnp-4682	49	9	whether	whether	SCONJ
fnp-4682	49	10	autonomic	autonomic	ADJ
fnp-4682	49	11	and	and	CCONJ
fnp-4682	49	12	sensory	sensory	ADJ
fnp-4682	49	13	symptoms	symptom	NOUN
fnp-4682	49	14	experienced	experience	VERB
fnp-4682	49	15	by	by	ADP
fnp-4682	49	16	pasc	pasc	ADJ
fnp-4682	49	17	patients	patient	NOUN
fnp-4682	49	18	can	can	AUX
fnp-4682	49	19	be	be	AUX
fnp-4682	49	20	attributed	attribute	VERB
fnp-4682	49	21	to	to	ADP
fnp-4682	49	22	small	small	ADJ
fnp-4682	49	23	fiber	fiber	NOUN
fnp-4682	49	24	neuropathy	neuropathy	ADJ
fnp-4682	49	25	(	(	PUNCT
fnp-4682	49	26	sfn	sfn	PROPN
fnp-4682	49	27	)	)	PUNCT
fnp-4682	49	28	.	.	PUNCT
fnp-4682	50	1	the	the	DET
fnp-4682	50	2	first	first	ADJ
fnp-4682	50	3	study	study	NOUN
fnp-4682	50	4	included	include	VERB
fnp-4682	50	5	13	13	NUM
fnp-4682	50	6	patients	patient	NOUN
fnp-4682	50	7	(	(	PUNCT
fnp-4682	50	8	8	8	NUM
fnp-4682	50	9	women	woman	NOUN
fnp-4682	50	10	and	and	CCONJ
fnp-4682	50	11	5	5	NUM
fnp-4682	50	12	men	man	NOUN
fnp-4682	50	13	)	)	PUNCT
fnp-4682	50	14	who	who	PRON
fnp-4682	50	15	had	have	VERB
fnp-4682	50	16	acute	acute	NOUN
fnp-4682	50	17	covid-19	covid-19	PROPN
fnp-4682	50	18	infection	infection	NOUN
fnp-4682	50	19	in	in	ADP
fnp-4682	50	20	march	march	PROPN
fnp-4682	50	21	-	-	PUNCT
fnp-4682	50	22	april	april	PROPN
fnp-4682	50	23	2020	2020	NUM
fnp-4682	50	24	and	and	CCONJ
fnp-4682	50	25	developed	develop	VERB
fnp-4682	50	26	paresthesias	paresthesia	NOUN
fnp-4682	50	27	0	0	NUM
fnp-4682	50	28	-	-	SYM
fnp-4682	50	29	2	2	NUM
fnp-4682	50	30	months	month	NOUN
fnp-4682	50	31	later	later	ADV
fnp-4682	50	32	;	;	PUNCT
fnp-4682	50	33	the	the	DET
fnp-4682	50	34	patients	patient	NOUN
fnp-4682	50	35	were	be	AUX
fnp-4682	50	36	evaluated	evaluate	VERB
fnp-4682	50	37	by	by	ADP
fnp-4682	50	38	electromyography	electromyography	NOUN
fnp-4682	50	39	/	/	SYM
fnp-4682	50	40	nerve	nerve	NOUN
fnp-4682	50	41	conduction	conduction	NOUN
fnp-4682	50	42	studies	study	NOUN
fnp-4682	50	43	(	(	PUNCT
fnp-4682	50	44	emg	emg	NOUN
fnp-4682	50	45	/	/	SYM
fnp-4682	50	46	ncs	ncs	PROPN
fnp-4682	50	47	)	)	PUNCT
fnp-4682	50	48	and	and	CCONJ
fnp-4682	50	49	two	two	NUM
fnp-4682	50	50	punch	punch	NOUN
fnp-4682	50	51	skin	skin	NOUN
fnp-4682	50	52	biopsies	biopsy	NOUN
fnp-4682	50	53	(	(	PUNCT
fnp-4682	50	54	from	from	ADP
fnp-4682	50	55	distal	distal	ADJ
fnp-4682	50	56	leg	leg	NOUN
fnp-4682	50	57	and	and	CCONJ
fnp-4682	50	58	proximal	proximal	ADJ
fnp-4682	50	59	thigh	thigh	NOUN
fnp-4682	50	60	)	)	PUNCT
fnp-4682	50	61	to	to	PART
fnp-4682	50	62	determine	determine	VERB
fnp-4682	50	63	intraepidermal	intraepidermal	ADJ
fnp-4682	50	64	nerve	nerve	NOUN
fnp-4682	50	65	fiber	fiber	NOUN
fnp-4682	50	66	density	density	NOUN
fnp-4682	50	67	(	(	PUNCT
fnp-4682	50	68	iefnd	iefnd	NOUN
fnp-4682	50	69	)	)	PUNCT
fnp-4682	50	70	(	(	PUNCT
fnp-4682	50	71	abrams	abrams	PROPN
fnp-4682	50	72	et	et	PROPN
fnp-4682	50	73	al	al	PROPN
fnp-4682	50	74	.	.	PROPN
fnp-4682	50	75	,	,	PUNCT
fnp-4682	50	76	2022	2022	NUM
fnp-4682	50	77	)	)	PUNCT
fnp-4682	50	78	.	.	PUNCT
fnp-4682	51	1	of	of	ADP
fnp-4682	51	2	these	these	DET
fnp-4682	51	3	13	13	NUM
fnp-4682	51	4	patients	patient	NOUN
fnp-4682	51	5	,	,	PUNCT
fnp-4682	51	6	only	only	ADV
fnp-4682	51	7	one	one	NUM
fnp-4682	51	8	had	have	VERB
fnp-4682	51	9	severe	severe	ADJ
fnp-4682	51	10	covid	covid	NOUN
fnp-4682	51	11	,	,	PUNCT
fnp-4682	51	12	and	and	CCONJ
fnp-4682	51	13	none	none	NOUN
fnp-4682	51	14	had	have	VERB
fnp-4682	51	15	a	a	DET
fnp-4682	51	16	history	history	NOUN
fnp-4682	51	17	of	of	ADP
fnp-4682	51	18	prior	prior	ADJ
fnp-4682	51	19	neurologic	neurologic	ADJ
fnp-4682	51	20	symptoms	symptom	NOUN
fnp-4682	51	21	or	or	CCONJ
fnp-4682	51	22	evidence	evidence	NOUN
fnp-4682	51	23	of	of	ADP
fnp-4682	51	24	large	large	ADJ
fnp-4682	51	25	fiber	fiber	NOUN
fnp-4682	51	26	polyneuropathy	polyneuropathy	NOUN
fnp-4682	51	27	on	on	ADP
fnp-4682	51	28	emg	emg	PROPN
fnp-4682	51	29	/	/	SYM
fnp-4682	51	30	ncs	ncs	PROPN
fnp-4682	51	31	.	.	PUNCT
fnp-4682	52	1	seven	seven	NUM
fnp-4682	52	2	of	of	ADP
fnp-4682	52	3	13	13	NUM
fnp-4682	52	4	patients	patient	NOUN
fnp-4682	52	5	also	also	ADV
fnp-4682	52	6	reported	report	VERB
fnp-4682	52	7	orthostatic	orthostatic	ADJ
fnp-4682	52	8	discomfort	discomfort	NOUN
fnp-4682	52	9	;	;	PUNCT
fnp-4682	52	10	four	four	NUM
fnp-4682	52	11	of	of	ADP
fnp-4682	52	12	these	these	DET
fnp-4682	52	13	seven	seven	NUM
fnp-4682	52	14	patients	patient	NOUN
fnp-4682	52	15	underwent	undergo	VERB
fnp-4682	52	16	autonomic	autonomic	ADJ
fnp-4682	52	17	function	function	NOUN
fnp-4682	52	18	testing	testing	NOUN
fnp-4682	52	19	,	,	PUNCT
fnp-4682	52	20	with	with	ADP
fnp-4682	52	21	abnormal	abnormal	ADJ
fnp-4682	52	22	findings	finding	NOUN
fnp-4682	52	23	reported	report	VERB
fnp-4682	52	24	in	in	ADP
fnp-4682	52	25	three	three	NUM
fnp-4682	52	26	.	.	PUNCT
fnp-4682	53	1	reduced	reduce	VERB
fnp-4682	53	2	iefnd	iefnd	NOUN
fnp-4682	53	3	was	be	AUX
fnp-4682	53	4	seen	see	VERB
fnp-4682	53	5	in	in	ADP
fnp-4682	53	6	46	46	NUM
fnp-4682	53	7	%	%	NOUN
fnp-4682	53	8	patients	patient	NOUN
fnp-4682	53	9	(	(	PUNCT
fnp-4682	53	10	6	6	NUM
fnp-4682	53	11	of	of	ADP
fnp-4682	53	12	13	13	NUM
fnp-4682	53	13	;	;	PUNCT
fnp-4682	53	14	all	all	DET
fnp-4682	53	15	female	female	NOUN
fnp-4682	53	16	)	)	PUNCT
fnp-4682	53	17	,	,	PUNCT
fnp-4682	53	18	all	all	PRON
fnp-4682	53	19	of	of	ADP
fnp-4682	53	20	whom	whom	PRON
fnp-4682	53	21	had	have	VERB
fnp-4682	53	22	clinical	clinical	ADJ
fnp-4682	53	23	findings	finding	NOUN
fnp-4682	53	24	consistent	consistent	ADJ
fnp-4682	53	25	with	with	ADP
fnp-4682	53	26	sfn	sfn	PROPN
fnp-4682	53	27	(	(	PUNCT
fnp-4682	53	28	mainly	mainly	ADV
fnp-4682	53	29	a	a	DET
fnp-4682	53	30	decreased	decrease	VERB
fnp-4682	53	31	pinprick	pinprick	NOUN
fnp-4682	53	32	sensation	sensation	NOUN
fnp-4682	53	33	in	in	ADP
fnp-4682	53	34	distal	distal	ADJ
fnp-4682	53	35	legs	leg	NOUN
fnp-4682	53	36	)	)	PUNCT
fnp-4682	53	37	;	;	PUNCT
fnp-4682	53	38	the	the	DET
fnp-4682	53	39	biopsy	biopsy	NOUN
fnp-4682	53	40	findings	finding	NOUN
fnp-4682	53	41	were	be	AUX
fnp-4682	53	42	also	also	ADV
fnp-4682	53	43	more	more	ADV
fnp-4682	53	44	severe	severe	ADJ
fnp-4682	53	45	distally	distally	ADV
fnp-4682	53	46	.	.	PUNCT
fnp-4682	54	1	in	in	ADP
fnp-4682	54	2	contrast	contrast	NOUN
fnp-4682	54	3	,	,	PUNCT
fnp-4682	54	4	most	most	ADJ
fnp-4682	54	5	patients	patient	NOUN
fnp-4682	54	6	with	with	ADP
fnp-4682	54	7	normal	normal	ADJ
fnp-4682	54	8	biopsy	biopsy	NOUN
fnp-4682	54	9	results	result	NOUN
fnp-4682	54	10	showed	show	VERB
fnp-4682	54	11	no	no	DET
fnp-4682	54	12	objective	objective	ADJ
fnp-4682	54	13	sensory	sensory	ADJ
fnp-4682	54	14	abnormalities	abnormality	NOUN
fnp-4682	54	15	on	on	ADP
fnp-4682	54	16	neurologic	neurologic	ADJ
fnp-4682	54	17	exam	exam	NOUN
fnp-4682	54	18	.	.	PUNCT
fnp-4682	55	1	the	the	DET
fnp-4682	55	2	second	second	ADJ
fnp-4682	55	3	study	study	NOUN
fnp-4682	55	4	enrolled	enrol	VERB
fnp-4682	55	5	17	17	NUM
fnp-4682	55	6	patients	patient	NOUN
fnp-4682	55	7	(	(	PUNCT
fnp-4682	55	8	11	11	NUM
fnp-4682	55	9	women	woman	NOUN
fnp-4682	55	10	and	and	CCONJ
fnp-4682	55	11	6	6	NUM
fnp-4682	55	12	men	man	NOUN
fnp-4682	55	13	)	)	PUNCT
fnp-4682	55	14	who	who	PRON
fnp-4682	55	15	developed	develop	VERB
fnp-4682	55	16	covid-19	covid-19	PROPN
fnp-4682	55	17	between	between	ADP
fnp-4682	55	18	february	february	PROPN
fnp-4682	55	19	2020	2020	NUM
fnp-4682	55	20	and	and	CCONJ
fnp-4682	55	21	january	january	PROPN
fnp-4682	55	22	2021	2021	NUM
fnp-4682	55	23	and	and	CCONJ
fnp-4682	55	24	presented	present	VERB
fnp-4682	55	25	with	with	ADP
fnp-4682	55	26	new	new	ADJ
fnp-4682	55	27	neuropathy	neuropathy	ADJ
fnp-4682	55	28	symptoms	symptom	NOUN
fnp-4682	55	29	0.1	0.1	NUM
fnp-4682	55	30	to	to	PART
fnp-4682	55	31	14.9	14.9	NUM
fnp-4682	55	32	months	month	NOUN
fnp-4682	55	33	following	follow	VERB
fnp-4682	55	34	covid	covid	PROPN
fnp-4682	55	35	onset	onset	PROPN
fnp-4682	55	36	;	;	PUNCT
fnp-4682	55	37	again	again	ADV
fnp-4682	55	38	,	,	PUNCT
fnp-4682	55	39	only	only	ADV
fnp-4682	55	40	1	1	NUM
fnp-4682	55	41	of	of	ADP
fnp-4682	55	42	these	these	DET
fnp-4682	55	43	17	17	NUM
fnp-4682	55	44	patients	patient	NOUN
fnp-4682	55	45	had	have	VERB
fnp-4682	55	46	a	a	DET
fnp-4682	55	47	severe	severe	ADJ
fnp-4682	55	48	covid	covid	NOUN
fnp-4682	55	49	infection	infection	NOUN
fnp-4682	55	50	(	(	PUNCT
fnp-4682	55	51	oaklander	oaklander	NOUN
fnp-4682	55	52	et	et	NOUN
fnp-4682	55	53	al	al	PROPN
fnp-4682	55	54	.	.	PROPN
fnp-4682	55	55	,	,	PUNCT
fnp-4682	55	56	2022	2022	NUM
fnp-4682	55	57	)	)	PUNCT
fnp-4682	55	58	.	.	PUNCT
fnp-4682	56	1	in	in	ADP
fnp-4682	56	2	this	this	DET
fnp-4682	56	3	cohort	cohort	NOUN
fnp-4682	56	4	,	,	PUNCT
fnp-4682	56	5	16.7	16.7	NUM
fnp-4682	56	6	%	%	NOUN
fnp-4682	56	7	of	of	ADP
fnp-4682	56	8	electrodiagnostic	electrodiagnostic	ADJ
fnp-4682	56	9	studies	study	NOUN
fnp-4682	56	10	showed	show	VERB
fnp-4682	56	11	abnormal	abnormal	ADJ
fnp-4682	56	12	findings	finding	NOUN
fnp-4682	56	13	,	,	PUNCT
fnp-4682	56	14	while	while	SCONJ
fnp-4682	56	15	62.5	62.5	NUM
fnp-4682	56	16	%	%	NOUN
fnp-4682	56	17	of	of	ADP
fnp-4682	56	18	lower	low	ADJ
fnp-4682	56	19	leg	leg	NOUN
fnp-4682	56	20	skin	skin	NOUN
fnp-4682	56	21	biopsies	biopsy	NOUN
fnp-4682	56	22	and	and	CCONJ
fnp-4682	56	23	50	50	NUM
fnp-4682	56	24	%	%	NOUN
fnp-4682	56	25	of	of	ADP
fnp-4682	56	26	upper	upper	ADJ
fnp-4682	56	27	thigh	thigh	NOUN
fnp-4682	56	28	biopsies	biopsy	NOUN
fnp-4682	56	29	showed	show	VERB
fnp-4682	56	30	reduced	reduced	ADJ
fnp-4682	56	31	iefnd	iefnd	NOUN
fnp-4682	56	32	.	.	PUNCT
fnp-4682	57	1	importantly	importantly	ADV
fnp-4682	57	2	,	,	PUNCT
fnp-4682	57	3	in	in	ADP
fnp-4682	57	4	both	both	DET
fnp-4682	57	5	studies	study	NOUN
fnp-4682	57	6	the	the	DET
fnp-4682	57	7	clinicopathologic	clinicopathologic	ADJ
fnp-4682	57	8	evaluation	evaluation	NOUN
fnp-4682	57	9	was	be	AUX
fnp-4682	57	10	performed	perform	VERB
fnp-4682	57	11	with	with	ADP
fnp-4682	57	12	a	a	DET
fnp-4682	57	13	significant	significant	ADJ
fnp-4682	57	14	delay	delay	NOUN
fnp-4682	57	15	due	due	ADP
fnp-4682	57	16	to	to	ADP
fnp-4682	57	17	pandemic	pandemic	ADJ
fnp-4682	57	18	-	-	PUNCT
fnp-4682	57	19	related	relate	VERB
fnp-4682	57	20	disruptions	disruption	NOUN
fnp-4682	57	21	in	in	ADP
fnp-4682	57	22	health	health	NOUN
fnp-4682	57	23	care	care	NOUN
fnp-4682	57	24	delivery	delivery	NOUN
fnp-4682	57	25	;	;	PUNCT
fnp-4682	57	26	thus	thus	ADV
fnp-4682	57	27	,	,	PUNCT
fnp-4682	57	28	it	it	PRON
fnp-4682	57	29	is	be	AUX
fnp-4682	57	30	possible	possible	ADJ
fnp-4682	57	31	that	that	SCONJ
fnp-4682	57	32	partial	partial	ADJ
fnp-4682	57	33	or	or	CCONJ
fnp-4682	57	34	complete	complete	ADJ
fnp-4682	57	35	small	small	ADJ
fnp-4682	57	36	fiber	fiber	NOUN
fnp-4682	57	37	recovery	recovery	NOUN
fnp-4682	57	38	occurred	occur	VERB
fnp-4682	57	39	in	in	ADP
fnp-4682	57	40	some	some	DET
fnp-4682	57	41	patients	patient	NOUN
fnp-4682	57	42	in	in	ADP
fnp-4682	57	43	the	the	DET
fnp-4682	57	44	interval	interval	NOUN
fnp-4682	57	45	between	between	ADP
fnp-4682	57	46	the	the	DET
fnp-4682	57	47	symptom	symptom	NOUN
fnp-4682	57	48	onset	onset	NOUN
fnp-4682	57	49	and	and	CCONJ
fnp-4682	57	50	assessment	assessment	NOUN
fnp-4682	57	51	,	,	PUNCT
fnp-4682	57	52	leading	lead	VERB
fnp-4682	57	53	to	to	ADP
fnp-4682	57	54	false	false	ADJ
fnp-4682	57	55	-	-	PUNCT
fnp-4682	57	56	negative	negative	ADJ
fnp-4682	57	57	test	test	NOUN
fnp-4682	57	58	results	result	NOUN
fnp-4682	57	59	.	.	PUNCT
fnp-4682	58	1	both	both	DET
fnp-4682	58	2	studies	study	NOUN
fnp-4682	58	3	should	should	AUX
fnp-4682	58	4	be	be	AUX
fnp-4682	58	5	considered	consider	VERB
fnp-4682	58	6	preliminary	preliminary	ADJ
fnp-4682	58	7	given	give	VERB
fnp-4682	58	8	their	their	PRON
fnp-4682	58	9	small	small	ADJ
fnp-4682	58	10	size	size	NOUN
fnp-4682	58	11	and	and	CCONJ
fnp-4682	58	12	confounding	confound	VERB
fnp-4682	58	13	by	by	ADP
fnp-4682	58	14	referral	referral	ADJ
fnp-4682	58	15	bias	bias	NOUN
fnp-4682	58	16	;	;	PUNCT
fnp-4682	58	17	however	however	ADV
fnp-4682	58	18	,	,	PUNCT
fnp-4682	58	19	the	the	DET
fnp-4682	58	20	reported	report	VERB
fnp-4682	58	21	findings	finding	NOUN
fnp-4682	58	22	are	be	AUX
fnp-4682	58	23	very	very	ADV
fnp-4682	58	24	similar	similar	ADJ
fnp-4682	58	25	and	and	CCONJ
fnp-4682	58	26	–	–	PUNCT
fnp-4682	58	27	if	if	SCONJ
fnp-4682	58	28	conformed	conform	VERB
fnp-4682	58	29	in	in	ADP
fnp-4682	58	30	larger	large	ADJ
fnp-4682	58	31	cohorts	cohort	NOUN
fnp-4682	58	32	–	–	PUNCT
fnp-4682	58	33	suggest	suggest	VERB
fnp-4682	58	34	that	that	SCONJ
fnp-4682	58	35	the	the	DET
fnp-4682	58	36	pasc	pasc	ADV
fnp-4682	58	37	-	-	PUNCT
fnp-4682	58	38	associated	associate	VERB
fnp-4682	58	39	peripheral	peripheral	ADJ
fnp-4682	58	40	neuropathy	neuropathy	ADJ
fnp-4682	58	41	reflects	reflect	VERB
fnp-4682	58	42	small	small	ADJ
fnp-4682	58	43	nerve	nerve	NOUN
fnp-4682	58	44	fiber	fiber	NOUN
fnp-4682	58	45	injury	injury	NOUN
fnp-4682	58	46	.	.	PUNCT
fnp-4682	59	1	the	the	DET
fnp-4682	59	2	underlying	underlie	VERB
fnp-4682	59	3	disease	disease	NOUN
fnp-4682	59	4	mechanisms	mechanism	NOUN
fnp-4682	59	5	also	also	ADV
fnp-4682	59	6	remain	remain	VERB
fnp-4682	59	7	to	to	PART
fnp-4682	59	8	be	be	AUX
fnp-4682	59	9	determined	determine	VERB
fnp-4682	59	10	;	;	PUNCT
fnp-4682	59	11	however	however	ADV
fnp-4682	59	12	,	,	PUNCT
fnp-4682	59	13	a	a	DET
fnp-4682	59	14	delay	delay	NOUN
fnp-4682	59	15	between	between	ADP
fnp-4682	59	16	covid	covid	PROPN
fnp-4682	59	17	infection	infection	NOUN
fnp-4682	59	18	and	and	CCONJ
fnp-4682	59	19	neurologic	neurologic	ADJ
fnp-4682	59	20	symptom	symptom	NOUN
fnp-4682	59	21	onset	onset	VERB
fnp-4682	59	22	in	in	ADP
fnp-4682	59	23	all	all	PRON
fnp-4682	59	24	but	but	SCONJ
fnp-4682	59	25	one	one	NUM
fnp-4682	59	26	of	of	ADP
fnp-4682	59	27	these	these	DET
fnp-4682	59	28	30	30	NUM
fnp-4682	59	29	pa	pa	PROPN
fnp-4682	59	30	-	-	PUNCT
fnp-4682	59	31	tients	tient	NOUN
fnp-4682	59	32	,	,	PUNCT
fnp-4682	59	33	along	along	ADP
fnp-4682	59	34	with	with	ADP
fnp-4682	59	35	therapeutic	therapeutic	ADJ
fnp-4682	59	36	effectiveness	effectiveness	NOUN
fnp-4682	59	37	of	of	ADP
fnp-4682	59	38	the	the	DET
fnp-4682	59	39	repeated	repeat	VERB
fnp-4682	59	40	ivig	ivig	NOUN
fnp-4682	59	41	treatment	treatment	NOUN
fnp-4682	59	42	in	in	ADP
fnp-4682	59	43	5	5	NUM
fnp-4682	59	44	patients	patient	NOUN
fnp-4682	59	45	who	who	PRON
fnp-4682	59	46	received	receive	VERB
fnp-4682	59	47	it	it	PRON
fnp-4682	59	48	,	,	PUNCT
fnp-4682	59	49	suggest	suggest	VERB
fnp-4682	59	50	that	that	SCONJ
fnp-4682	59	51	the	the	DET
fnp-4682	59	52	pasc	pasc	ADV
fnp-4682	59	53	-	-	PUNCT
fnp-4682	59	54	associated	associate	VERB
fnp-4682	59	55	sfn	sfn	PROPN
fnp-4682	59	56	is	be	AUX
fnp-4682	59	57	due	due	ADJ
fnp-4682	59	58	to	to	ADP
fnp-4682	59	59	post	post	ADJ
fnp-4682	59	60	-	-	ADJ
fnp-4682	59	61	infectious	infectious	ADJ
fnp-4682	59	62	dysregulation	dysregulation	NOUN
fnp-4682	59	63	of	of	ADP
fnp-4682	59	64	the	the	DET
fnp-4682	59	65	immune	immune	ADJ
fnp-4682	59	66	system	system	NOUN
fnp-4682	59	67	.	.	PUNCT
fnp-4682	60	1	persistent	persistent	ADJ
fnp-4682	60	2	fatigue	fatigue	NOUN
fnp-4682	60	3	is	be	AUX
fnp-4682	60	4	experienced	experience	VERB
fnp-4682	60	5	by	by	ADP
fnp-4682	60	6	50	50	NUM
fnp-4682	60	7	-	-	SYM
fnp-4682	60	8	70	70	NUM
fnp-4682	60	9	%	%	NOUN
fnp-4682	60	10	of	of	ADP
fnp-4682	60	11	pasc	pasc	ADJ
fnp-4682	60	12	patients	patient	NOUN
fnp-4682	60	13	,	,	PUNCT
fnp-4682	60	14	making	make	VERB
fnp-4682	60	15	it	it	PRON
fnp-4682	60	16	one	one	NUM
fnp-4682	60	17	of	of	ADP
fnp-4682	60	18	the	the	DET
fnp-4682	60	19	most	most	ADV
fnp-4682	60	20	common	common	ADJ
fnp-4682	60	21	pasc	pasc	ADJ
fnp-4682	60	22	symptoms	symptom	NOUN
fnp-4682	60	23	.	.	PUNCT
fnp-4682	61	1	however	however	ADV
fnp-4682	61	2	,	,	PUNCT
fnp-4682	61	3	it	it	PRON
fnp-4682	61	4	has	have	AUX
fnp-4682	61	5	been	be	AUX
fnp-4682	61	6	challenging	challenge	VERB
fnp-4682	61	7	to	to	PART
fnp-4682	61	8	determine	determine	VERB
fnp-4682	61	9	whether	whether	SCONJ
fnp-4682	61	10	this	this	DET
fnp-4682	61	11	relatively	relatively	ADV
fnp-4682	61	12	subjective	subjective	ADJ
fnp-4682	61	13	and	and	CCONJ
fnp-4682	61	14	nonspecific	nonspecific	ADJ
fnp-4682	61	15	clinical	clinical	ADJ
fnp-4682	61	16	symptom	symptom	NOUN
fnp-4682	61	17	is	be	AUX
fnp-4682	61	18	caused	cause	VERB
fnp-4682	61	19	by	by	ADP
fnp-4682	61	20	functional	functional	ADJ
fnp-4682	61	21	response	response	NOUN
fnp-4682	61	22	of	of	ADP
fnp-4682	61	23	muscle	muscle	NOUN
fnp-4682	61	24	tissue	tissue	NOUN
fnp-4682	61	25	to	to	ADP
fnp-4682	61	26	circulating	circulate	VERB
fnp-4682	61	27	inflammatory	inflammatory	ADJ
fnp-4682	61	28	mediators	mediator	NOUN
fnp-4682	61	29	,	,	PUNCT
fnp-4682	61	30	microcirculatory	microcirculatory	ADJ
fnp-4682	61	31	abnormalities	abnormality	NOUN
fnp-4682	61	32	,	,	PUNCT
fnp-4682	61	33	or	or	CCONJ
fnp-4682	61	34	an	an	DET
fnp-4682	61	35	underlying	underlie	VERB
fnp-4682	61	36	skeletal	skeletal	ADJ
fnp-4682	61	37	myopathy	myopathy	NOUN
fnp-4682	61	38	.	.	PUNCT
fnp-4682	62	1	to	to	PART
fnp-4682	62	2	start	start	VERB
fnp-4682	62	3	addressing	address	VERB
fnp-4682	62	4	this	this	DET
fnp-4682	62	5	question	question	NOUN
fnp-4682	62	6	,	,	PUNCT
fnp-4682	62	7	hejbøl	hejbøl	ADJ
fnp-4682	62	8	and	and	CCONJ
fnp-4682	62	9	colleagues	colleague	NOUN
fnp-4682	62	10	evaluated	evaluate	VERB
fnp-4682	62	11	16	16	NUM
fnp-4682	62	12	patients	patient	NOUN
fnp-4682	62	13	(	(	PUNCT
fnp-4682	62	14	13	13	NUM
fnp-4682	62	15	women	woman	NOUN
fnp-4682	62	16	and	and	CCONJ
fnp-4682	62	17	3	3	NUM
fnp-4682	62	18	men	man	NOUN
fnp-4682	62	19	)	)	PUNCT
fnp-4682	62	20	with	with	ADP
fnp-4682	62	21	chronic	chronic	ADJ
fnp-4682	62	22	post	post	ADJ
fnp-4682	62	23	-	-	ADJ
fnp-4682	62	24	covid	covid	ADJ
fnp-4682	62	25	fatigue	fatigue	NOUN
fnp-4682	62	26	;	;	PUNCT
fnp-4682	62	27	none	none	NOUN
fnp-4682	62	28	of	of	ADP
fnp-4682	62	29	the	the	DET
fnp-4682	62	30	patients	patient	NOUN
fnp-4682	62	31	had	have	AUX
fnp-4682	62	32	been	be	AUX
fnp-4682	62	33	severely	severely	ADV
fnp-4682	62	34	ill	ill	ADJ
fnp-4682	62	35	with	with	ADP
fnp-4682	62	36	covid	covid	PROPN
fnp-4682	62	37	or	or	CCONJ
fnp-4682	62	38	hospitalized	hospitalize	VERB
fnp-4682	62	39	in	in	ADP
fnp-4682	62	40	intensive	intensive	ADJ
fnp-4682	62	41	care	care	NOUN
fnp-4682	62	42	unit	unit	NOUN
fnp-4682	62	43	,	,	PUNCT
fnp-4682	62	44	and	and	CCONJ
fnp-4682	62	45	clinicopathologic	clinicopathologic	ADJ
fnp-4682	62	46	evaluation	evaluation	NOUN
fnp-4682	62	47	for	for	ADP
fnp-4682	62	48	myopathy	myopathy	ADJ
fnp-4682	62	49	(	(	PUNCT
fnp-4682	62	50	which	which	PRON
fnp-4682	62	51	included	include	VERB
fnp-4682	62	52	quantitative	quantitative	ADJ
fnp-4682	62	53	emg	emg	NOUN
fnp-4682	62	54	and	and	CCONJ
fnp-4682	62	55	skeletal	skeletal	ADJ
fnp-4682	62	56	muscle	muscle	NOUN
fnp-4682	62	57	biopsy	biopsy	NOUN
fnp-4682	62	58	)	)	PUNCT
fnp-4682	62	59	occurred	occur	VERB
fnp-4682	62	60	5	5	NUM
fnp-4682	62	61	-	-	SYM
fnp-4682	62	62	14	14	NUM
fnp-4682	62	63	months	month	NOUN
fnp-4682	62	64	following	follow	VERB
fnp-4682	62	65	acute	acute	ADJ
fnp-4682	62	66	infection	infection	NOUN
fnp-4682	62	67	(	(	PUNCT
fnp-4682	62	68	hejbøl	hejbøl	PROPN
fnp-4682	62	69	et	et	PROPN
fnp-4682	62	70	al	al	PROPN
fnp-4682	62	71	.	.	PROPN
fnp-4682	62	72	,	,	PUNCT
fnp-4682	62	73	2022	2022	NUM
fnp-4682	62	74	)	)	PUNCT
fnp-4682	62	75	.	.	PUNCT
fnp-4682	63	1	among	among	ADP
fnp-4682	63	2	these	these	DET
fnp-4682	63	3	16	16	NUM
fnp-4682	63	4	patients	patient	NOUN
fnp-4682	63	5	with	with	ADP
fnp-4682	63	6	pasc	pasc	ADJ
fnp-4682	63	7	fatigue	fatigue	NOUN
fnp-4682	63	8	,	,	PUNCT
fnp-4682	63	9	69	69	NUM
fnp-4682	63	10	%	%	NOUN
fnp-4682	63	11	also	also	ADV
fnp-4682	63	12	had	have	VERB
fnp-4682	63	13	paresthesias	paresthesia	NOUN
fnp-4682	63	14	,	,	PUNCT
fnp-4682	63	15	but	but	CCONJ
fnp-4682	63	16	none	none	NOUN
fnp-4682	63	17	had	have	VERB
fnp-4682	63	18	abnormal	abnormal	ADJ
fnp-4682	63	19	deep	deep	ADJ
fnp-4682	63	20	tendon	tendon	NOUN
fnp-4682	63	21	reflexes	reflex	NOUN
fnp-4682	63	22	or	or	CCONJ
fnp-4682	63	23	altered	alter	VERB
fnp-4682	63	24	vibratory	vibratory	ADJ
fnp-4682	63	25	sensation	sensation	NOUN
fnp-4682	63	26	,	,	PUNCT
fnp-4682	63	27	and	and	CCONJ
fnp-4682	63	28	ncs	ncs	NOUN
fnp-4682	63	29	were	be	AUX
fnp-4682	63	30	normal	normal	ADJ
fnp-4682	63	31	in	in	ADP
fnp-4682	63	32	all	all	DET
fnp-4682	63	33	16	16	NUM
fnp-4682	63	34	.	.	PUNCT
fnp-4682	64	1	in	in	ADP
fnp-4682	64	2	addition	addition	NOUN
fnp-4682	64	3	to	to	ADP
fnp-4682	64	4	the	the	DET
fnp-4682	64	5	fatigue	fatigue	NOUN
fnp-4682	64	6	,	,	PUNCT
fnp-4682	64	7	81	81	NUM
fnp-4682	64	8	%	%	NOUN
fnp-4682	64	9	of	of	ADP
fnp-4682	64	10	study	study	NOUN
fnp-4682	64	11	patients	patient	NOUN
fnp-4682	64	12	had	have	VERB
fnp-4682	64	13	myalgia	myalgia	NOUN
fnp-4682	64	14	,	,	PUNCT
fnp-4682	64	15	50	50	NUM
fnp-4682	64	16	%	%	NOUN
fnp-4682	64	17	objective	objective	ADJ
fnp-4682	64	18	muscle	muscle	NOUN
fnp-4682	64	19	weakness	weakness	NOUN
fnp-4682	64	20	,	,	PUNCT
fnp-4682	64	21	and	and	CCONJ
fnp-4682	64	22	75	75	NUM
fnp-4682	64	23	%	%	NOUN
fnp-4682	64	24	myopathic	myopathic	ADJ
fnp-4682	64	25	findings	finding	NOUN
fnp-4682	64	26	on	on	ADP
fnp-4682	64	27	emg	emg	NOUN
fnp-4682	64	28	;	;	PUNCT
fnp-4682	64	29	serologic	serologic	ADJ
fnp-4682	64	30	studies	study	NOUN
fnp-4682	64	31	were	be	AUX
fnp-4682	64	32	generally	generally	ADV
fnp-4682	64	33	unremarkable	unremarkable	ADJ
fnp-4682	64	34	,	,	PUNCT
fnp-4682	64	35	except	except	SCONJ
fnp-4682	64	36	for	for	ADP
fnp-4682	64	37	one	one	NUM
fnp-4682	64	38	patient	patient	NOUN
fnp-4682	64	39	with	with	ADP
fnp-4682	64	40	a	a	DET
fnp-4682	64	41	marginally	marginally	ADV
fnp-4682	64	42	elevated	elevate	VERB
fnp-4682	64	43	creatine	creatine	NOUN
fnp-4682	64	44	kinase	kinase	PROPN
fnp-4682	64	45	level	level	NOUN
fnp-4682	64	46	and	and	CCONJ
fnp-4682	64	47	another	another	PRON
fnp-4682	64	48	with	with	ADP
fnp-4682	64	49	elevated	elevated	ADJ
fnp-4682	64	50	tif1	tif1	NOUN
fnp-4682	64	51	-	-	PUNCT
fnp-4682	64	52	γ	γ	NOUN
fnp-4682	64	53	antibody	antibody	NOUN
fnp-4682	64	54	titer	titer	NOUN
fnp-4682	64	55	but	but	CCONJ
fnp-4682	64	56	normal	normal	ADJ
fnp-4682	64	57	creatine	creatine	NOUN
fnp-4682	64	58	kinase	kinase	PROPN
fnp-4682	64	59	level	level	NOUN
fnp-4682	64	60	.	.	PUNCT
fnp-4682	65	1	remarkably	remarkably	ADV
fnp-4682	65	2	,	,	PUNCT
fnp-4682	65	3	muscle	muscle	NOUN
fnp-4682	65	4	biopsies	biopsy	NOUN
fnp-4682	65	5	from	from	ADP
fnp-4682	65	6	all	all	DET
fnp-4682	65	7	16	16	NUM
fnp-4682	65	8	patients	patient	NOUN
fnp-4682	65	9	showed	show	VERB
fnp-4682	65	10	histologic	histologic	ADJ
fnp-4682	65	11	and/or	and/or	CCONJ
fnp-4682	65	12	ultrastructural	ultrastructural	ADJ
fnp-4682	65	13	muscle	muscle	NOUN
fnp-4682	65	14	fiber	fiber	NOUN
fnp-4682	65	15	pathology	pathology	NOUN
fnp-4682	65	16	;	;	PUNCT
fnp-4682	65	17	the	the	DET
fnp-4682	65	18	findings	finding	NOUN
fnp-4682	65	19	were	be	AUX
fnp-4682	65	20	variable	variable	ADJ
fnp-4682	65	21	,	,	PUNCT
fnp-4682	65	22	but	but	CCONJ
fnp-4682	65	23	included	include	VERB
fnp-4682	65	24	prominent	prominent	ADJ
fnp-4682	65	25	nucleoli	nucleolus	NOUN
fnp-4682	65	26	and	and	CCONJ
fnp-4682	65	27	non	non	ADJ
fnp-4682	65	28	-	-	ADJ
fnp-4682	65	29	selective	selective	ADJ
fnp-4682	65	30	fiber	fiber	NOUN
fnp-4682	65	31	atrophy	atrophy	NOUN
fnp-4682	65	32	(	(	PUNCT
fnp-4682	65	33	suggestive	suggestive	ADJ
fnp-4682	65	34	of	of	ADP
fnp-4682	65	35	fiber	fiber	NOUN
fnp-4682	65	36	regeneration	regeneration	NOUN
fnp-4682	65	37	)	)	PUNCT
fnp-4682	65	38	,	,	PUNCT
fnp-4682	65	39	basal	basal	VERB
fnp-4682	65	40	lamina	lamina	ADJ
fnp-4682	65	41	reduplication	reduplication	NOUN
fnp-4682	65	42	,	,	PUNCT
fnp-4682	65	43	myofibrillar	myofibrillar	ADJ
fnp-4682	65	44	disorganization	disorganization	NOUN
fnp-4682	65	45	,	,	PUNCT
fnp-4682	65	46	and	and	CCONJ
fnp-4682	65	47	mitochondrial	mitochondrial	ADJ
fnp-4682	65	48	abnormalities	abnormality	NOUN
fnp-4682	65	49	(	(	PUNCT
fnp-4682	65	50	fig	fig	NOUN
fnp-4682	65	51	.	.	PUNCT
fnp-4682	66	1	2	2	NUM
fnp-4682	66	2	)	)	PUNCT
fnp-4682	66	3	.	.	PUNCT
fnp-4682	67	1	in	in	ADP
fnp-4682	67	2	addition	addition	NOUN
fnp-4682	67	3	,	,	PUNCT
fnp-4682	67	4	inflammation	inflammation	NOUN
fnp-4682	67	5	and/or	and/or	CCONJ
fnp-4682	67	6	mhc	mhc	PROPN
fnp-4682	67	7	-	-	PUNCT
fnp-4682	67	8	i	i	PRON
fnp-4682	67	9	upregulation	upregulation	NOUN
fnp-4682	67	10	was	be	AUX
fnp-4682	67	11	present	present	ADJ
fnp-4682	67	12	in	in	ADP
fnp-4682	67	13	62	62	NUM
fnp-4682	67	14	%	%	NOUN
fnp-4682	67	15	of	of	ADP
fnp-4682	67	16	biopsies	biopsy	NOUN
fnp-4682	67	17	,	,	PUNCT
fnp-4682	67	18	while	while	SCONJ
fnp-4682	67	19	capillary	capillary	ADJ
fnp-4682	67	20	abnormalities	abnormality	NOUN
fnp-4682	67	21	(	(	PUNCT
fnp-4682	67	22	including	include	VERB
fnp-4682	67	23	basal	basal	ADJ
fnp-4682	67	24	lamina	lamina	ADJ
fnp-4682	67	25	reduplication	reduplication	NOUN
fnp-4682	67	26	and	and	CCONJ
fnp-4682	67	27	capillary	capillary	ADJ
fnp-4682	67	28	loss	loss	NOUN
fnp-4682	67	29	/	/	SYM
fnp-4682	67	30	degeneration	degeneration	NOUN
fnp-4682	67	31	)	)	PUNCT
fnp-4682	67	32	were	be	AUX
fnp-4682	67	33	detected	detect	VERB
fnp-4682	67	34	in	in	ADP
fnp-4682	67	35	75	75	NUM
fnp-4682	67	36	%	%	NOUN
fnp-4682	67	37	of	of	ADP
fnp-4682	67	38	biopsies	biopsy	NOUN
fnp-4682	67	39	.	.	PUNCT
fnp-4682	68	1	finally	finally	ADV
fnp-4682	68	2	,	,	PUNCT
fnp-4682	68	3	one	one	NUM
fnp-4682	68	4	patient	patient	NOUN
fnp-4682	68	5	showed	show	VERB
fnp-4682	68	6	a	a	DET
fnp-4682	68	7	loss	loss	NOUN
fnp-4682	68	8	of	of	ADP
fnp-4682	68	9	non	non	ADJ
fnp-4682	68	10	-	-	ADJ
fnp-4682	68	11	myelinated	myelinated	ADJ
fnp-4682	68	12	,	,	PUNCT
fnp-4682	68	13	small	small	ADJ
fnp-4682	68	14	caliber	caliber	NOUN
fnp-4682	68	15	axons	axon	NOUN
fnp-4682	68	16	in	in	ADP
fnp-4682	68	17	the	the	DET
fnp-4682	68	18	intramuscular	intramuscular	ADJ
fnp-4682	68	19	nerve	nerve	NOUN
fnp-4682	68	20	twigs	twig	NOUN
fnp-4682	68	21	.	.	PUNCT
fnp-4682	69	1	the	the	DET
fnp-4682	69	2	spectrum	spectrum	NOUN
fnp-4682	69	3	of	of	ADP
fnp-4682	69	4	findings	finding	NOUN
fnp-4682	69	5	seen	see	VERB
fnp-4682	69	6	in	in	ADP
fnp-4682	69	7	these	these	DET
fnp-4682	69	8	specimens	specimen	NOUN
fnp-4682	69	9	is	be	AUX
fnp-4682	69	10	very	very	ADV
fnp-4682	69	11	broad	broad	ADJ
fnp-4682	69	12	and	and	CCONJ
fnp-4682	69	13	does	do	AUX
fnp-4682	69	14	not	not	PART
fnp-4682	69	15	point	point	VERB
fnp-4682	69	16	to	to	ADP
fnp-4682	69	17	a	a	DET
fnp-4682	69	18	specific	specific	ADJ
fnp-4682	69	19	disease	disease	NOUN
fnp-4682	69	20	mechanism	mechanism	NOUN
fnp-4682	69	21	;	;	PUNCT
fnp-4682	69	22	however	however	ADV
fnp-4682	69	23	,	,	PUNCT
fnp-4682	69	24	both	both	CCONJ
fnp-4682	69	25	mitochondrial	mitochondrial	ADJ
fnp-4682	69	26	and	and	CCONJ
fnp-4682	69	27	capillary	capillary	ADJ
fnp-4682	69	28	pathology	pathology	NOUN
fnp-4682	69	29	could	could	AUX
fnp-4682	69	30	provide	provide	VERB
fnp-4682	69	31	an	an	DET
fnp-4682	69	32	explanation	explanation	NOUN
fnp-4682	69	33	for	for	ADP
fnp-4682	69	34	fatigue	fatigue	NOUN
fnp-4682	69	35	,	,	PUNCT
fnp-4682	69	36	while	while	SCONJ
fnp-4682	69	37	basal	basal	ADJ
fnp-4682	69	38	lamina	lamina	ADJ
fnp-4682	69	39	reduplication	reduplication	NOUN
fnp-4682	69	40	could	could	AUX
fnp-4682	69	41	be	be	AUX
fnp-4682	69	42	due	due	ADJ
fnp-4682	69	43	to	to	ADP
fnp-4682	69	44	increased	increase	VERB
fnp-4682	69	45	tgfβ	tgfβ	NOUN
fnp-4682	69	46	(	(	PUNCT
fnp-4682	69	47	transforming	transform	VERB
fnp-4682	69	48	growth	growth	NOUN
fnp-4682	69	49	factor	factor	NOUN
fnp-4682	69	50	β	β	NOUN
fnp-4682	69	51	)	)	PUNCT
fnp-4682	69	52	levels	level	NOUN
fnp-4682	69	53	,	,	PUNCT
fnp-4682	69	54	which	which	PRON
fnp-4682	69	55	often	often	ADV
fnp-4682	69	56	accompany	accompany	VERB
fnp-4682	69	57	chronic	chronic	ADJ
fnp-4682	69	58	low	low	ADJ
fnp-4682	69	59	-	-	PUNCT
fnp-4682	69	60	grade	grade	NOUN
fnp-4682	69	61	inflammation	inflammation	NOUN
fnp-4682	69	62	.	.	PUNCT
fnp-4682	70	1	like	like	ADP
fnp-4682	70	2	the	the	DET
fnp-4682	70	3	two	two	NUM
fnp-4682	70	4	sfn	sfn	PROPN
fnp-4682	70	5	studies	study	NOUN
fnp-4682	70	6	described	describe	VERB
fnp-4682	70	7	above	above	ADV
fnp-4682	70	8	,	,	PUNCT
fnp-4682	70	9	this	this	DET
fnp-4682	70	10	study	study	NOUN
fnp-4682	70	11	has	have	VERB
fnp-4682	70	12	several	several	ADJ
fnp-4682	70	13	important	important	ADJ
fnp-4682	70	14	limitations	limitation	NOUN
fnp-4682	70	15	,	,	PUNCT
fnp-4682	70	16	including	include	VERB
fnp-4682	70	17	small	small	ADJ
fnp-4682	70	18	cohort	cohort	NOUN
fnp-4682	70	19	size	size	NOUN
fnp-4682	70	20	,	,	PUNCT
fnp-4682	70	21	lack	lack	NOUN
fnp-4682	70	22	of	of	ADP
fnp-4682	70	23	patients	patient	NOUN
fnp-4682	70	24	from	from	ADP
fnp-4682	70	25	later	later	ADJ
fnp-4682	70	26	stages	stage	NOUN
fnp-4682	70	27	of	of	ADP
fnp-4682	70	28	the	the	DET
fnp-4682	70	29	pandemic	pandemic	NOUN
fnp-4682	70	30	(	(	PUNCT
fnp-4682	70	31	who	who	PRON
fnp-4682	70	32	were	be	AUX
fnp-4682	70	33	infected	infect	VERB
fnp-4682	70	34	by	by	ADP
fnp-4682	70	35	sars	sar	NOUN
fnp-4682	70	36	-	-	PUNCT
fnp-4682	70	37	cov-2	cov-2	PART
fnp-4682	70	38	variants	variant	NOUN
fnp-4682	70	39	other	other	ADJ
fnp-4682	70	40	than	than	ADP
fnp-4682	70	41	the	the	DET
fnp-4682	70	42	ancestral	ancestral	ADJ
fnp-4682	70	43	strain	strain	NOUN
fnp-4682	70	44	)	)	PUNCT
fnp-4682	70	45	,	,	PUNCT
fnp-4682	70	46	and	and	CCONJ
fnp-4682	70	47	lack	lack	NOUN
fnp-4682	70	48	of	of	ADP
fnp-4682	70	49	a	a	DET
fnp-4682	70	50	control	control	NOUN
fnp-4682	70	51	group	group	NOUN
fnp-4682	70	52	(	(	PUNCT
fnp-4682	70	53	i.e.	i.e.	X
fnp-4682	70	54	,	,	PUNCT
fnp-4682	70	55	patients	patient	NOUN
fnp-4682	70	56	with	with	ADP
fnp-4682	70	57	covid-19	covid-19	PROPN
fnp-4682	70	58	who	who	PRON
fnp-4682	70	59	did	do	AUX
fnp-4682	70	60	not	not	PART
fnp-4682	70	61	develop	develop	VERB
fnp-4682	70	62	fatigue	fatigue	NOUN
fnp-4682	70	63	or	or	CCONJ
fnp-4682	70	64	other	other	ADJ
fnp-4682	70	65	pasc	pasc	ADJ
fnp-4682	70	66	symptoms	symptom	NOUN
fnp-4682	70	67	)	)	PUNCT
fnp-4682	70	68	;	;	PUNCT
fnp-4682	70	69	nonetheless	nonetheless	ADV
fnp-4682	70	70	,	,	PUNCT
fnp-4682	70	71	the	the	DET
fnp-4682	70	72	findings	finding	NOUN
fnp-4682	70	73	suggest	suggest	VERB
fnp-4682	70	74	that	that	SCONJ
fnp-4682	70	75	muscle	muscle	NOUN
fnp-4682	70	76	biopsy	biopsy	NOUN
fnp-4682	70	77	is	be	AUX
fnp-4682	70	78	the	the	DET
fnp-4682	70	79	most	most	ADV
fnp-4682	70	80	sensitive	sensitive	ADJ
fnp-4682	70	81	test	test	NOUN
fnp-4682	70	82	for	for	ADP
fnp-4682	70	83	diagnosis	diagnosis	NOUN
fnp-4682	70	84	of	of	ADP
fnp-4682	70	85	the	the	DET
fnp-4682	70	86	pasc	pasc	ADV
fnp-4682	70	87	-	-	PUNCT
fnp-4682	70	88	associated	associate	VERB
fnp-4682	70	89	myopathy	myopathy	ADJ
fnp-4682	70	90	.	.	PUNCT
fnp-4682	71	1	figure	figure	NOUN
fnp-4682	71	2	2	2	NUM
fnp-4682	71	3	.	.	NOUN
fnp-4682	71	4	myopathy	myopathy	ADJ
fnp-4682	71	5	as	as	ADP
fnp-4682	71	6	a	a	DET
fnp-4682	71	7	cause	cause	NOUN
fnp-4682	71	8	of	of	ADP
fnp-4682	71	9	fatigue	fatigue	NOUN
fnp-4682	71	10	in	in	ADP
fnp-4682	71	11	long	long	ADJ
fnp-4682	71	12	-	-	PUNCT
fnp-4682	71	13	term	term	NOUN
fnp-4682	71	14	post	post	ADJ
fnp-4682	71	15	-	-	ADJ
fnp-4682	71	16	covid-19	covid-19	ADJ
fnp-4682	71	17	symptoms	symptom	NOUN
fnp-4682	71	18	:	:	PUNCT
fnp-4682	71	19	histopathological	histopathological	ADJ
fnp-4682	71	20	changes	change	NOUN
fnp-4682	71	21	in	in	ADP
fnp-4682	71	22	muscle	muscle	NOUN
fnp-4682	71	23	fibers	fiber	NOUN
fnp-4682	71	24	.	.	PUNCT
fnp-4682	72	1	(	(	PUNCT
fnp-4682	72	2	a	a	PRON
fnp-4682	72	3	,	,	PUNCT
fnp-4682	72	4	b	b	NOUN
fnp-4682	72	5	)	)	PUNCT
fnp-4682	72	6	muscle	muscle	NOUN
fnp-4682	72	7	fiber	fiber	NOUN
fnp-4682	72	8	atrophy	atrophy	NOUN
fnp-4682	72	9	.	.	PUNCT
fnp-4682	73	1	(	(	PUNCT
fnp-4682	73	2	a	a	X
fnp-4682	73	3	)	)	PUNCT
fnp-4682	73	4	atrophic	atrophic	ADJ
fnp-4682	73	5	fiber	fiber	NOUN
fnp-4682	73	6	and	and	CCONJ
fnp-4682	73	7	(	(	PUNCT
fnp-4682	73	8	b	b	NOUN
fnp-4682	73	9	)	)	PUNCT
fnp-4682	73	10	folds	fold	NOUN
fnp-4682	73	11	in	in	ADP
fnp-4682	73	12	the	the	DET
fnp-4682	73	13	basal	basal	NOUN
fnp-4682	73	14	lamina	lamina	PROPN
fnp-4682	73	15	,	,	PUNCT
fnp-4682	73	16	both	both	PRON
fnp-4682	73	17	in	in	ADP
fnp-4682	73	18	patient	patient	NOUN
fnp-4682	73	19	9	9	NUM
fnp-4682	73	20	.	.	PUNCT
fnp-4682	74	1	(	(	PUNCT
fnp-4682	74	2	c	c	X
fnp-4682	74	3	–	–	PUNCT
fnp-4682	74	4	f	f	X
fnp-4682	74	5	)	)	PUNCT
fnp-4682	74	6	muscle	muscle	NOUN
fnp-4682	74	7	fiber	fiber	NOUN
fnp-4682	74	8	damage	damage	NOUN
fnp-4682	74	9	indicated	indicate	VERB
fnp-4682	74	10	by	by	ADP
fnp-4682	74	11	basal	basal	ADJ
fnp-4682	74	12	lamina	lamina	ADJ
fnp-4682	74	13	proliferation	proliferation	NOUN
fnp-4682	74	14	.	.	PUNCT
fnp-4682	75	1	(	(	PUNCT
fnp-4682	75	2	c	c	X
fnp-4682	75	3	)	)	PUNCT
fnp-4682	75	4	basal	basal	VERB
fnp-4682	75	5	lamina	lamina	ADJ
fnp-4682	75	6	duplication	duplication	NOUN
fnp-4682	75	7	(	(	PUNCT
fnp-4682	75	8	arrow	arrow	NOUN
fnp-4682	75	9	)	)	PUNCT
fnp-4682	75	10	in	in	ADP
fnp-4682	75	11	patient	patient	NOUN
fnp-4682	75	12	16	16	NUM
fnp-4682	75	13	.	.	PUNCT
fnp-4682	76	1	(	(	PUNCT
fnp-4682	76	2	d	d	NOUN
fnp-4682	76	3	,	,	PUNCT
fnp-4682	76	4	e	e	NOUN
fnp-4682	76	5	)	)	PUNCT
fnp-4682	76	6	multiple	multiple	ADJ
fnp-4682	76	7	myofiber	myofiber	NOUN
fnp-4682	76	8	basal	basal	ADJ
fnp-4682	76	9	lamina	lamina	NOUN
fnp-4682	76	10	(	(	PUNCT
fnp-4682	76	11	d	d	NOUN
fnp-4682	76	12	)	)	PUNCT
fnp-4682	76	13	and	and	CCONJ
fnp-4682	76	14	(	(	PUNCT
fnp-4682	76	15	e	e	NOUN
fnp-4682	76	16	)	)	PUNCT
fnp-4682	76	17	higher	high	ADJ
fnp-4682	76	18	magnification	magnification	NOUN
fnp-4682	76	19	showing	show	VERB
fnp-4682	76	20	continuity	continuity	NOUN
fnp-4682	76	21	between	between	ADP
fnp-4682	76	22	the	the	DET
fnp-4682	76	23	different	different	ADJ
fnp-4682	76	24	layers	layer	NOUN
fnp-4682	76	25	(	(	PUNCT
fnp-4682	76	26	arrows	arrow	NOUN
fnp-4682	76	27	)	)	PUNCT
fnp-4682	76	28	in	in	ADP
fnp-4682	76	29	patient	patient	NOUN
fnp-4682	76	30	14	14	NUM
fnp-4682	76	31	.	.	PUNCT
fnp-4682	77	1	(	(	PUNCT
fnp-4682	77	2	f	f	X
fnp-4682	77	3	)	)	PUNCT
fnp-4682	77	4	from	from	ADP
fnp-4682	77	5	patient	patient	NOUN
fnp-4682	77	6	6	6	NUM
fnp-4682	77	7	,	,	PUNCT
fnp-4682	77	8	showing	show	VERB
fnp-4682	77	9	aggregation	aggregation	NOUN
fnp-4682	77	10	of	of	ADP
fnp-4682	77	11	nuclei	nucleus	NOUN
fnp-4682	77	12	,	,	PUNCT
fnp-4682	77	13	and	and	CCONJ
fnp-4682	77	14	multiple	multiple	ADJ
fnp-4682	77	15	layers	layer	NOUN
fnp-4682	77	16	of	of	ADP
fnp-4682	77	17	myofiber	myofiber	PROPN
fnp-4682	77	18	basal	basal	ADJ
fnp-4682	77	19	lamina	lamina	NOUN
fnp-4682	77	20	(	(	PUNCT
fnp-4682	77	21	arrow	arrow	NOUN
fnp-4682	77	22	)	)	PUNCT
fnp-4682	77	23	.	.	PUNCT
fnp-4682	78	1	(	(	PUNCT
fnp-4682	78	2	g	g	NOUN
fnp-4682	78	3	–	–	PUNCT
fnp-4682	78	4	i	i	NOUN
fnp-4682	78	5	)	)	PUNCT
fnp-4682	78	6	myofibrillary	myofibrillary	ADJ
fnp-4682	78	7	disorganization	disorganization	NOUN
fnp-4682	78	8	:	:	PUNCT
fnp-4682	78	9	(	(	PUNCT
fnp-4682	78	10	g	g	NOUN
fnp-4682	78	11	)	)	PUNCT
fnp-4682	78	12	streaming	streaming	NOUN
fnp-4682	78	13	of	of	ADP
fnp-4682	78	14	z	z	NOUN
fnp-4682	78	15	-	-	PUNCT
fnp-4682	78	16	bands	band	NOUN
fnp-4682	78	17	in	in	ADP
fnp-4682	78	18	patient	patient	NOUN
fnp-4682	78	19	14	14	NUM
fnp-4682	78	20	,	,	PUNCT
fnp-4682	78	21	(	(	PUNCT
fnp-4682	78	22	h	h	NOUN
fnp-4682	78	23	)	)	PUNCT
fnp-4682	78	24	disorganized	disorganized	ADJ
fnp-4682	78	25	myofibrils	myofibril	NOUN
fnp-4682	78	26	in	in	ADP
fnp-4682	78	27	patient	patient	ADJ
fnp-4682	78	28	13	13	NUM
fnp-4682	78	29	,	,	PUNCT
fnp-4682	78	30	and	and	CCONJ
fnp-4682	78	31	(	(	PUNCT
fnp-4682	78	32	i	i	NOUN
fnp-4682	78	33	)	)	PUNCT
fnp-4682	78	34	myofibril	myofibril	NOUN
fnp-4682	78	35	disorganization	disorganization	NOUN
fnp-4682	78	36	and	and	CCONJ
fnp-4682	78	37	a	a	DET
fnp-4682	78	38	cytoplasmic	cytoplasmic	ADJ
fnp-4682	78	39	body	body	NOUN
fnp-4682	78	40	in	in	ADP
fnp-4682	78	41	patient	patient	ADJ
fnp-4682	78	42	1	1	NUM
fnp-4682	78	43	.	.	PUNCT
fnp-4682	78	44	(	(	PUNCT
fnp-4682	78	45	j	j	NOUN
fnp-4682	78	46	–	–	PUNCT
fnp-4682	78	47	l	l	NOUN
fnp-4682	78	48	)	)	PUNCT
fnp-4682	78	49	mitochondrial	mitochondrial	ADJ
fnp-4682	78	50	changes	change	NOUN
fnp-4682	78	51	:	:	PUNCT
fnp-4682	78	52	(	(	PUNCT
fnp-4682	78	53	j	j	NOUN
fnp-4682	78	54	)	)	PUNCT
fnp-4682	78	55	a	a	DET
fnp-4682	78	56	cytochrome	cytochrome	NOUN
fnp-4682	78	57	c	c	NOUN
fnp-4682	78	58	oxidase	oxidase	NOUN
fnp-4682	78	59	-	-	PUNCT
fnp-4682	78	60	negative	negative	ADJ
fnp-4682	78	61	fiber	fiber	NOUN
fnp-4682	78	62	(	(	PUNCT
fnp-4682	78	63	blue	blue	ADJ
fnp-4682	78	64	)	)	PUNCT
fnp-4682	78	65	and	and	CCONJ
fnp-4682	78	66	(	(	PUNCT
fnp-4682	78	67	k	k	NOUN
fnp-4682	78	68	)	)	PUNCT
fnp-4682	78	69	subsarcolemmal	subsarcolemmal	ADJ
fnp-4682	78	70	accumulation	accumulation	NOUN
fnp-4682	78	71	of	of	ADP
fnp-4682	78	72	structurally	structurally	ADV
fnp-4682	78	73	abnormal	abnormal	ADJ
fnp-4682	78	74	mitochondria	mitochondria	NOUN
fnp-4682	78	75	from	from	ADP
fnp-4682	78	76	patient	patient	ADJ
fnp-4682	78	77	8	8	NUM
fnp-4682	78	78	,	,	PUNCT
fnp-4682	78	79	and	and	CCONJ
fnp-4682	78	80	(	(	PUNCT
fnp-4682	78	81	l	l	NOUN
fnp-4682	78	82	)	)	PUNCT
fnp-4682	78	83	subsarcolemmal	subsarcolemmal	ADJ
fnp-4682	78	84	accumulation	accumulation	NOUN
fnp-4682	78	85	of	of	ADP
fnp-4682	78	86	ultrastructural	ultrastructural	ADJ
fnp-4682	78	87	normal	normal	ADJ
fnp-4682	78	88	-	-	PUNCT
fnp-4682	78	89	appearing	appear	VERB
fnp-4682	78	90	mitochondria	mitochondria	NOUN
fnp-4682	78	91	in	in	ADP
fnp-4682	78	92	patient	patient	ADJ
fnp-4682	78	93	9	9	NUM
fnp-4682	78	94	.	.	PUNCT
fnp-4682	78	95	scale	scale	NOUN
fnp-4682	78	96	bars	bar	NOUN
fnp-4682	78	97	:	:	PUNCT
fnp-4682	78	98	k	k	X
fnp-4682	79	1	=	=	SYM
fnp-4682	80	1	500	500	NUM
fnp-4682	80	2	nm	nm	NOUN
fnp-4682	80	3	;	;	PUNCT
fnp-4682	80	4	c	c	X
fnp-4682	80	5	,	,	PUNCT
fnp-4682	80	6	e	e	NOUN
fnp-4682	80	7	,	,	PUNCT
fnp-4682	80	8	h	h	NOUN
fnp-4682	80	9	,	,	PUNCT
fnp-4682	80	10	and	and	CCONJ
fnp-4682	80	11	l	l	NOUN
fnp-4682	80	12	=	=	SYM
fnp-4682	80	13	1	1	NUM
fnp-4682	80	14	μm	μm	NOUN
fnp-4682	80	15	;	;	PUNCT
fnp-4682	80	16	a	a	PRON
fnp-4682	80	17	,	,	PUNCT
fnp-4682	80	18	b	b	NOUN
fnp-4682	80	19	,	,	PUNCT
fnp-4682	80	20	d	d	PROPN
fnp-4682	80	21	,	,	PUNCT
fnp-4682	80	22	f	f	X
fnp-4682	80	23	,	,	PUNCT
fnp-4682	80	24	g	g	PROPN
fnp-4682	80	25	,	,	PUNCT
fnp-4682	80	26	and	and	CCONJ
fnp-4682	80	27	i	i	NOUN
fnp-4682	80	28	=	=	NOUN
fnp-4682	80	29	2	2	NUM
fnp-4682	80	30	μm	μm	NUM
fnp-4682	80	31	;	;	PUNCT
fnp-4682	80	32	j	j	PROPN
fnp-4682	80	33	=	=	NOUN
fnp-4682	80	34	100	100	NUM
fnp-4682	80	35	μm	μm	NOUN
fnp-4682	80	36	.	.	PUNCT
fnp-4682	81	1	[	[	X
fnp-4682	81	2	this	this	DET
fnp-4682	81	3	figure	figure	NOUN
fnp-4682	81	4	and	and	CCONJ
fnp-4682	81	5	its	its	PRON
fnp-4682	81	6	legend	legend	NOUN
fnp-4682	81	7	are	be	AUX
fnp-4682	81	8	reproduced	reproduce	VERB
fnp-4682	81	9	without	without	ADP
fnp-4682	81	10	modifications	modification	NOUN
fnp-4682	81	11	from	from	ADP
fnp-4682	81	12	(	(	PUNCT
fnp-4682	81	13	hejbøl	hejbøl	PROPN
fnp-4682	81	14	et	et	PROPN
fnp-4682	81	15	al	al	PROPN
fnp-4682	81	16	.	.	PROPN
fnp-4682	81	17	,	,	PUNCT
fnp-4682	81	18	2022	2022	NUM
fnp-4682	81	19	)	)	PUNCT
fnp-4682	81	20	;	;	PUNCT
fnp-4682	81	21	this	this	DET
fnp-4682	81	22	use	use	NOUN
fnp-4682	81	23	is	be	AUX
fnp-4682	81	24	permitted	permit	VERB
fnp-4682	81	25	under	under	ADP
fnp-4682	81	26	the	the	DET
fnp-4682	81	27	creative	creative	ADJ
fnp-4682	81	28	commons	common	NOUN
fnp-4682	81	29	attribution	attribution	NOUN
fnp-4682	81	30	4.0	4.0	NUM
fnp-4682	81	31	cc	cc	NOUN
fnp-4682	81	32	-	-	PUNCT
fnp-4682	81	33	by	by	ADP
fnp-4682	81	34	-	-	PUNCT
fnp-4682	81	35	nc	nc	VERB
fnp-4682	81	36	-	-	PUNCT
fnp-4682	81	37	nd	nd	ADV
fnp-4682	81	38	international	international	ADJ
fnp-4682	81	39	license	license	NOUN
fnp-4682	81	40	.	.	PUNCT
fnp-4682	81	41	]	]	PUNCT
fnp-4682	82	1	collectively	collectively	ADV
fnp-4682	82	2	,	,	PUNCT
fnp-4682	82	3	these	these	DET
fnp-4682	82	4	three	three	NUM
fnp-4682	82	5	studies	study	NOUN
fnp-4682	82	6	provide	provide	VERB
fnp-4682	82	7	initial	initial	ADJ
fnp-4682	82	8	evidence	evidence	NOUN
fnp-4682	82	9	that	that	SCONJ
fnp-4682	82	10	neuromuscular	neuromuscular	ADJ
fnp-4682	82	11	symptoms	symptom	NOUN
fnp-4682	82	12	commonly	commonly	ADV
fnp-4682	82	13	seen	see	VERB
fnp-4682	82	14	in	in	ADP
fnp-4682	82	15	pasc	pasc	ADJ
fnp-4682	82	16	patients	patient	NOUN
fnp-4682	82	17	are	be	AUX
fnp-4682	82	18	associated	associate	VERB
fnp-4682	82	19	with	with	ADP
fnp-4682	82	20	–	–	PUNCT
fnp-4682	82	21	and	and	CCONJ
fnp-4682	82	22	likely	likely	ADV
fnp-4682	82	23	attributable	attributable	ADJ
fnp-4682	82	24	to	to	ADP
fnp-4682	82	25	–	–	PUNCT
fnp-4682	82	26	structural	structural	ADJ
fnp-4682	82	27	abnormalities	abnormality	NOUN
fnp-4682	82	28	of	of	ADP
fnp-4682	82	29	peripheral	peripheral	ADJ
fnp-4682	82	30	nerves	nerve	NOUN
fnp-4682	82	31	and	and	CCONJ
fnp-4682	82	32	skeletal	skeletal	ADJ
fnp-4682	82	33	muscles	muscle	NOUN
fnp-4682	82	34	;	;	PUNCT
fnp-4682	82	35	however	however	ADV
fnp-4682	82	36	,	,	PUNCT
fnp-4682	82	37	these	these	DET
fnp-4682	82	38	preliminary	preliminary	ADJ
fnp-4682	82	39	findings	finding	NOUN
fnp-4682	82	40	should	should	AUX
fnp-4682	82	41	be	be	AUX
fnp-4682	82	42	replicated	replicate	VERB
fnp-4682	82	43	in	in	ADP
fnp-4682	82	44	larger	large	ADJ
fnp-4682	82	45	and	and	CCONJ
fnp-4682	82	46	temporally	temporally	ADV
fnp-4682	82	47	more	more	ADV
fnp-4682	82	48	homogenous	homogenous	ADJ
fnp-4682	82	49	cohorts	cohort	NOUN
fnp-4682	82	50	of	of	ADP
fnp-4682	82	51	pasc	pasc	ADJ
fnp-4682	82	52	patients	patient	NOUN
fnp-4682	82	53	.	.	PUNCT
fnp-4682	83	1	furthermore	furthermore	ADV
fnp-4682	83	2	,	,	PUNCT
fnp-4682	83	3	additional	additional	ADJ
fnp-4682	83	4	work	work	NOUN
fnp-4682	83	5	is	be	AUX
fnp-4682	83	6	required	require	VERB
fnp-4682	83	7	to	to	PART
fnp-4682	83	8	establish	establish	VERB
fnp-4682	83	9	whether	whether	SCONJ
fnp-4682	83	10	similar	similar	ADJ
fnp-4682	83	11	nerve	nerve	NOUN
fnp-4682	83	12	and	and	CCONJ
fnp-4682	83	13	muscle	muscle	NOUN
fnp-4682	83	14	abnormalities	abnormality	NOUN
fnp-4682	83	15	are	be	AUX
fnp-4682	83	16	detectable	detectable	ADJ
fnp-4682	83	17	in	in	ADP
fnp-4682	83	18	patients	patient	NOUN
fnp-4682	83	19	with	with	ADP
fnp-4682	83	20	myalgic	myalgic	ADJ
fnp-4682	83	21	encephalomyelitis	encephalomyelitis	NOUN
fnp-4682	83	22	/	/	SYM
fnp-4682	83	23	chronic	chronic	ADJ
fnp-4682	83	24	fatigue	fatigue	NOUN
fnp-4682	83	25	syndrome	syndrome	NOUN
fnp-4682	83	26	,	,	PUNCT
fnp-4682	83	27	which	which	PRON
fnp-4682	83	28	shares	share	VERB
fnp-4682	83	29	many	many	ADJ
fnp-4682	83	30	clinical	clinical	ADJ
fnp-4682	83	31	features	feature	NOUN
fnp-4682	83	32	with	with	ADP
fnp-4682	83	33	the	the	DET
fnp-4682	83	34	pasc	pasc	ADJ
fnp-4682	83	35	syndrome	syndrome	NOUN
fnp-4682	83	36	.	.	PUNCT
fnp-4682	84	1	3	3	X
fnp-4682	84	2	.	.	X
fnp-4682	84	3	dnajb4	dnajb4	ADJ
fnp-4682	84	4	-	-	PUNCT
fnp-4682	84	5	associated	associated	ADJ
fnp-4682	84	6	myopathy	myopathy	ADJ
fnp-4682	84	7	:	:	PUNCT
fnp-4682	84	8	a	a	DET
fnp-4682	84	9	new	new	ADJ
fnp-4682	84	10	chaperonopathy	chaperonopathy	ADJ
fnp-4682	84	11	molecular	molecular	ADJ
fnp-4682	84	12	chaperones	chaperone	NOUN
fnp-4682	84	13	play	play	VERB
fnp-4682	84	14	a	a	DET
fnp-4682	84	15	key	key	ADJ
fnp-4682	84	16	role	role	NOUN
fnp-4682	84	17	in	in	ADP
fnp-4682	84	18	the	the	DET
fnp-4682	84	19	maintenance	maintenance	NOUN
fnp-4682	84	20	of	of	ADP
fnp-4682	84	21	protein	protein	NOUN
fnp-4682	84	22	homeostasis	homeostasis	NOUN
fnp-4682	84	23	by	by	ADP
fnp-4682	84	24	facilitating	facilitate	VERB
fnp-4682	84	25	folding	folding	NOUN
fnp-4682	84	26	of	of	ADP
fnp-4682	84	27	newly	newly	ADV
fnp-4682	84	28	synthetized	synthetize	VERB
fnp-4682	84	29	proteins	protein	NOUN
fnp-4682	84	30	and	and	CCONJ
fnp-4682	84	31	degradation	degradation	NOUN
fnp-4682	84	32	of	of	ADP
fnp-4682	84	33	misfolded	misfolde	VERB
fnp-4682	84	34	or	or	CCONJ
fnp-4682	84	35	damaged	damage	VERB
fnp-4682	84	36	/	/	SYM
fnp-4682	84	37	unfolded	unfold	VERB
fnp-4682	84	38	proteins	protein	NOUN
fnp-4682	84	39	;	;	PUNCT
fnp-4682	84	40	the	the	DET
fnp-4682	84	41	latter	latter	ADJ
fnp-4682	84	42	role	role	NOUN
fnp-4682	84	43	is	be	AUX
fnp-4682	84	44	particularly	particularly	ADV
fnp-4682	84	45	critical	critical	ADJ
fnp-4682	84	46	in	in	ADP
fnp-4682	84	47	skeletal	skeletal	ADJ
fnp-4682	84	48	muscle	muscle	NOUN
fnp-4682	84	49	,	,	PUNCT
fnp-4682	84	50	where	where	SCONJ
fnp-4682	84	51	mechanical	mechanical	ADJ
fnp-4682	84	52	stress	stress	NOUN
fnp-4682	84	53	leads	lead	VERB
fnp-4682	84	54	to	to	ADP
fnp-4682	84	55	constant	constant	ADJ
fnp-4682	84	56	damage	damage	NOUN
fnp-4682	84	57	to	to	ADP
fnp-4682	84	58	sarcomeric	sarcomeric	ADJ
fnp-4682	84	59	proteins	protein	NOUN
fnp-4682	84	60	and	and	CCONJ
fnp-4682	84	61	where	where	SCONJ
fnp-4682	84	62	misfolded	misfolde	VERB
fnp-4682	84	63	protein	protein	NOUN
fnp-4682	84	64	aggregates	aggregate	NOUN
fnp-4682	84	65	can	can	AUX
fnp-4682	84	66	not	not	PART
fnp-4682	84	67	be	be	AUX
fnp-4682	84	68	diluted	dilute	VERB
fnp-4682	84	69	through	through	ADP
fnp-4682	84	70	cell	cell	NOUN
fnp-4682	84	71	division	division	NOUN
fnp-4682	84	72	.	.	PUNCT
fnp-4682	85	1	as	as	ADP
fnp-4682	85	2	a	a	DET
fnp-4682	85	3	result	result	NOUN
fnp-4682	85	4	,	,	PUNCT
fnp-4682	85	5	although	although	SCONJ
fnp-4682	85	6	chaperones	chaperone	NOUN
fnp-4682	85	7	and	and	CCONJ
fnp-4682	85	8	co	co	NOUN
fnp-4682	85	9	-	-	NOUN
fnp-4682	85	10	chaperones	chaperone	NOUN
fnp-4682	85	11	are	be	AUX
fnp-4682	85	12	ubiquitously	ubiquitously	ADV
fnp-4682	85	13	expressed	express	VERB
fnp-4682	85	14	proteins	protein	NOUN
fnp-4682	85	15	,	,	PUNCT
fnp-4682	85	16	skeletal	skeletal	ADJ
fnp-4682	85	17	myopathy	myopathy	NOUN
fnp-4682	85	18	is	be	AUX
fnp-4682	85	19	generally	generally	ADV
fnp-4682	85	20	the	the	DET
fnp-4682	85	21	main	main	ADJ
fnp-4682	85	22	(	(	PUNCT
fnp-4682	85	23	and	and	CCONJ
fnp-4682	85	24	often	often	ADV
fnp-4682	85	25	only	only	ADV
fnp-4682	85	26	)	)	PUNCT
fnp-4682	85	27	clinical	clinical	ADJ
fnp-4682	85	28	manifestation	manifestation	NOUN
fnp-4682	85	29	of	of	ADP
fnp-4682	85	30	many	many	ADJ
fnp-4682	85	31	chaperonopathies	chaperonopathie	NOUN
fnp-4682	85	32	.	.	PUNCT
fnp-4682	86	1	dnaj	dnaj	PROPN
fnp-4682	86	2	/	/	SYM
fnp-4682	86	3	hsp40	hsp40	PROPN
fnp-4682	86	4	co	co	NOUN
fnp-4682	86	5	-	-	NOUN
fnp-4682	86	6	chaperones	chaperone	NOUN
fnp-4682	86	7	determine	determine	VERB
fnp-4682	86	8	the	the	DET
fnp-4682	86	9	specificity	specificity	NOUN
fnp-4682	86	10	of	of	ADP
fnp-4682	86	11	the	the	DET
fnp-4682	86	12	chaperone	chaperone	NOUN
fnp-4682	86	13	/	/	SYM
fnp-4682	86	14	client	client	NOUN
fnp-4682	86	15	interaction	interaction	NOUN
fnp-4682	86	16	and	and	CCONJ
fnp-4682	86	17	are	be	AUX
fnp-4682	86	18	highly	highly	ADV
fnp-4682	86	19	evolutionarily	evolutionarily	ADV
fnp-4682	86	20	conserved	conserve	VERB
fnp-4682	86	21	from	from	ADP
fnp-4682	86	22	yeast	yeast	NOUN
fnp-4682	86	23	to	to	ADP
fnp-4682	86	24	humans	human	NOUN
fnp-4682	86	25	;	;	PUNCT
fnp-4682	86	26	mutations	mutation	NOUN
fnp-4682	86	27	in	in	ADP
fnp-4682	86	28	several	several	ADJ
fnp-4682	86	29	dnaj	dnaj	NOUN
fnp-4682	86	30	co	co	NOUN
fnp-4682	86	31	-	-	NOUN
fnp-4682	86	32	chaperones	chaperone	NOUN
fnp-4682	86	33	from	from	ADP
fnp-4682	86	34	the	the	DET
fnp-4682	86	35	b	b	PROPN
fnp-4682	86	36	family	family	NOUN
fnp-4682	86	37	(	(	PUNCT
fnp-4682	86	38	dnajb2	dnajb2	NOUN
fnp-4682	86	39	,	,	PUNCT
fnp-4682	86	40	dnajb5	dnajb5	PROPN
fnp-4682	86	41	and	and	CCONJ
fnp-4682	86	42	dnajb6	dnajb6	NOUN
fnp-4682	86	43	)	)	PUNCT
fnp-4682	86	44	cause	cause	VERB
fnp-4682	86	45	neuromuscular	neuromuscular	ADJ
fnp-4682	86	46	disease	disease	NOUN
fnp-4682	86	47	,	,	PUNCT
fnp-4682	86	48	but	but	CCONJ
fnp-4682	86	49	prior	prior	ADV
fnp-4682	86	50	to	to	ADP
fnp-4682	86	51	2022	2022	NUM
fnp-4682	86	52	no	no	DET
fnp-4682	86	53	human	human	ADJ
fnp-4682	86	54	disease	disease	NOUN
fnp-4682	86	55	has	have	AUX
fnp-4682	86	56	been	be	AUX
fnp-4682	86	57	linked	link	VERB
fnp-4682	86	58	to	to	ADP
fnp-4682	86	59	dnajb4	dnajb4	PROPN
fnp-4682	86	60	.	.	PUNCT
fnp-4682	87	1	dnajb6	dnajb6	NOUN
fnp-4682	87	2	is	be	AUX
fnp-4682	87	3	a	a	DET
fnp-4682	87	4	close	close	ADJ
fnp-4682	87	5	homolog	homolog	NOUN
fnp-4682	87	6	of	of	ADP
fnp-4682	87	7	dnajb4	dnajb4	PROPN
fnp-4682	87	8	;	;	PUNCT
fnp-4682	87	9	it	it	PRON
fnp-4682	87	10	localizes	localize	VERB
fnp-4682	87	11	to	to	ADP
fnp-4682	87	12	the	the	DET
fnp-4682	87	13	z	z	NOUN
fnp-4682	87	14	-	-	PUNCT
fnp-4682	87	15	disc	disc	NOUN
fnp-4682	87	16	and	and	CCONJ
fnp-4682	87	17	,	,	PUNCT
fnp-4682	87	18	together	together	ADV
fnp-4682	87	19	with	with	ADP
fnp-4682	87	20	hspb8	hspb8	ADJ
fnp-4682	87	21	and	and	CCONJ
fnp-4682	87	22	bag3	bag3	PROPN
fnp-4682	87	23	,	,	PUNCT
fnp-4682	87	24	plays	play	VERB
fnp-4682	87	25	a	a	DET
fnp-4682	87	26	critical	critical	ADJ
fnp-4682	87	27	role	role	NOUN
fnp-4682	87	28	in	in	ADP
fnp-4682	87	29	the	the	DET
fnp-4682	87	30	z	z	NOUN
fnp-4682	87	31	-	-	PUNCT
fnp-4682	87	32	disc	disc	NOUN
fnp-4682	87	33	maintenance	maintenance	NOUN
fnp-4682	87	34	via	via	ADP
fnp-4682	87	35	chaperone	chaperone	NOUN
fnp-4682	87	36	-	-	PUNCT
fnp-4682	87	37	assisted	assist	VERB
fnp-4682	87	38	selective	selective	ADJ
fnp-4682	87	39	autophagy	autophagy	NOUN
fnp-4682	87	40	.	.	PUNCT
fnp-4682	88	1	autosomal	autosomal	ADJ
fnp-4682	88	2	dominant	dominant	ADJ
fnp-4682	88	3	mutations	mutation	NOUN
fnp-4682	88	4	in	in	ADP
fnp-4682	88	5	dnajb6	dnajb6	NOUN
fnp-4682	88	6	lead	lead	VERB
fnp-4682	88	7	to	to	ADP
fnp-4682	88	8	two	two	NUM
fnp-4682	88	9	distinct	distinct	ADJ
fnp-4682	88	10	clinical	clinical	ADJ
fnp-4682	88	11	phenotypes	phenotype	NOUN
fnp-4682	88	12	,	,	PUNCT
fnp-4682	88	13	limb	limb	NOUN
fnp-4682	88	14	-	-	PUNCT
fnp-4682	88	15	girdle	girdle	NOUN
fnp-4682	88	16	muscular	muscular	ADJ
fnp-4682	88	17	dystrophy	dystrophy	NOUN
fnp-4682	88	18	d1	d1	PROPN
fnp-4682	88	19	and	and	CCONJ
fnp-4682	88	20	distal	distal	ADJ
fnp-4682	88	21	myopathy	myopathy	ADJ
fnp-4682	88	22	,	,	PUNCT
fnp-4682	88	23	both	both	PRON
fnp-4682	88	24	of	of	ADP
fnp-4682	88	25	which	which	PRON
fnp-4682	88	26	are	be	AUX
fnp-4682	88	27	histologically	histologically	ADV
fnp-4682	88	28	characterized	characterize	VERB
fnp-4682	88	29	by	by	ADP
fnp-4682	88	30	myofibrillar	myofibrillar	ADJ
fnp-4682	88	31	disorganization	disorganization	NOUN
fnp-4682	88	32	,	,	PUNCT
fnp-4682	88	33	protein	protein	NOUN
fnp-4682	88	34	aggregates	aggregate	NOUN
fnp-4682	88	35	,	,	PUNCT
fnp-4682	88	36	and	and	CCONJ
fnp-4682	88	37	rimmed	rimmed	ADJ
fnp-4682	88	38	vacuoles	vacuole	NOUN
fnp-4682	88	39	(	(	PUNCT
fnp-4682	88	40	sarparanta	sarparanta	PROPN
fnp-4682	88	41	et	et	PROPN
fnp-4682	88	42	al	al	PROPN
fnp-4682	88	43	.	.	PROPN
fnp-4682	88	44	,	,	PUNCT
fnp-4682	88	45	2020	2020	NUM
fnp-4682	88	46	)	)	PUNCT
fnp-4682	88	47	.	.	PUNCT
fnp-4682	89	1	last	last	ADJ
fnp-4682	89	2	year	year	NOUN
fnp-4682	89	3	,	,	PUNCT
fnp-4682	89	4	two	two	NUM
fnp-4682	89	5	separate	separate	ADJ
fnp-4682	89	6	research	research	NOUN
fnp-4682	89	7	groups	group	NOUN
fnp-4682	89	8	showed	show	VERB
fnp-4682	89	9	that	that	SCONJ
fnp-4682	89	10	mutations	mutation	NOUN
fnp-4682	89	11	in	in	ADP
fnp-4682	89	12	dnajb4	dnajb4	ADJ
fnp-4682	89	13	cause	cause	VERB
fnp-4682	89	14	a	a	DET
fnp-4682	89	15	similar	similar	ADJ
fnp-4682	89	16	but	but	CCONJ
fnp-4682	89	17	distinct	distinct	ADJ
fnp-4682	89	18	skeletal	skeletal	ADJ
fnp-4682	89	19	myopathy	myopathy	NOUN
fnp-4682	89	20	that	that	PRON
fnp-4682	89	21	is	be	AUX
fnp-4682	89	22	inherited	inherit	VERB
fnp-4682	89	23	in	in	ADP
fnp-4682	89	24	either	either	CCONJ
fnp-4682	89	25	autosomal	autosomal	ADJ
fnp-4682	89	26	recessive	recessive	ADJ
fnp-4682	89	27	(	(	PUNCT
fnp-4682	89	28	ar	ar	NOUN
fnp-4682	89	29	;	;	PUNCT
fnp-4682	89	30	weihl	weihl	NOUN
fnp-4682	89	31	et	et	PROPN
fnp-4682	89	32	al	al	PROPN
fnp-4682	89	33	.	.	PROPN
fnp-4682	89	34	,	,	PUNCT
fnp-4682	89	35	2023	2023	NUM
fnp-4682	89	36	)	)	PUNCT
fnp-4682	89	37	or	or	CCONJ
fnp-4682	89	38	autosomal	autosomal	ADJ
fnp-4682	89	39	dominant	dominant	ADJ
fnp-4682	89	40	(	(	PUNCT
fnp-4682	89	41	ad	ad	NOUN
fnp-4682	89	42	;	;	PUNCT
fnp-4682	89	43	inoue	inoue	PROPN
fnp-4682	89	44	et	et	PROPN
fnp-4682	89	45	al	al	PROPN
fnp-4682	89	46	.	.	PROPN
fnp-4682	89	47	,	,	PUNCT
fnp-4682	89	48	2023	2023	NUM
fnp-4682	89	49	)	)	PUNCT
fnp-4682	89	50	manner	manner	NOUN
fnp-4682	89	51	.	.	PUNCT
fnp-4682	90	1	weihl	weihl	NOUN
fnp-4682	90	2	and	and	CCONJ
fnp-4682	90	3	co	co	NOUN
fnp-4682	90	4	-	-	NOUN
fnp-4682	90	5	authors	author	NOUN
fnp-4682	90	6	used	use	VERB
fnp-4682	90	7	a	a	DET
fnp-4682	90	8	reverse	reverse	ADJ
fnp-4682	90	9	genetic	genetic	ADJ
fnp-4682	90	10	approach	approach	NOUN
fnp-4682	90	11	to	to	PART
fnp-4682	90	12	identify	identify	VERB
fnp-4682	90	13	four	four	NUM
fnp-4682	90	14	patients	patient	NOUN
fnp-4682	90	15	from	from	ADP
fnp-4682	90	16	three	three	NUM
fnp-4682	90	17	different	different	ADJ
fnp-4682	90	18	families	family	NOUN
fnp-4682	90	19	who	who	PRON
fnp-4682	90	20	carry	carry	VERB
fnp-4682	90	21	autosomal	autosomal	ADJ
fnp-4682	90	22	recessive	recessive	ADJ
fnp-4682	90	23	,	,	PUNCT
fnp-4682	90	24	loss	loss	NOUN
fnp-4682	90	25	-	-	PUNCT
fnp-4682	90	26	of	of	ADP
fnp-4682	90	27	-	-	PUNCT
fnp-4682	90	28	function	function	NOUN
fnp-4682	90	29	mutations	mutation	NOUN
fnp-4682	90	30	in	in	ADP
fnp-4682	90	31	dnajb4	dnajb4	PROPN
fnp-4682	90	32	that	that	SCONJ
fnp-4682	90	33	either	either	CCONJ
fnp-4682	90	34	severely	severely	ADV
fnp-4682	90	35	abrogate	abrogate	VERB
fnp-4682	90	36	protein	protein	NOUN
fnp-4682	90	37	expression	expression	NOUN
fnp-4682	90	38	(	(	PUNCT
fnp-4682	90	39	c.856a	c.856a	PROPN
fnp-4682	90	40	>	>	X
fnp-4682	90	41	t	t	PROPN
fnp-4682	90	42	;	;	PUNCT
fnp-4682	90	43	p.lys286ter	p.lys286ter	NOUN
fnp-4682	90	44	and	and	CCONJ
fnp-4682	90	45	c.785t	c.785t	PROPN
fnp-4682	90	46	>	>	PROPN
fnp-4682	90	47	c	c	PROPN
fnp-4682	90	48	;	;	PUNCT
fnp-4682	90	49	p.leu262ser	p.leu262ser	NOUN
fnp-4682	90	50	)	)	PUNCT
fnp-4682	90	51	or	or	CCONJ
fnp-4682	90	52	lead	lead	VERB
fnp-4682	90	53	to	to	ADP
fnp-4682	90	54	expression	expression	NOUN
fnp-4682	90	55	of	of	ADP
fnp-4682	90	56	a	a	DET
fnp-4682	90	57	non	non	ADJ
fnp-4682	90	58	-	-	ADJ
fnp-4682	90	59	functional	functional	ADJ
fnp-4682	90	60	protein	protein	NOUN
fnp-4682	90	61	(	(	PUNCT
fnp-4682	90	62	c.74g	c.74g	NOUN
fnp-4682	90	63	>	>	X
fnp-4682	90	64	a	a	PRON
fnp-4682	90	65	;	;	PUNCT
fnp-4682	90	66	p.arg25gln	p.arg25gln	NOUN
fnp-4682	90	67	)	)	PUNCT
fnp-4682	90	68	.	.	PUNCT
fnp-4682	91	1	clinically	clinically	ADV
fnp-4682	91	2	,	,	PUNCT
fnp-4682	91	3	these	these	DET
fnp-4682	91	4	patients	patient	NOUN
fnp-4682	91	5	presented	present	VERB
fnp-4682	91	6	in	in	ADP
fnp-4682	91	7	the	the	DET
fnp-4682	91	8	first	first	ADJ
fnp-4682	91	9	decades	decade	NOUN
fnp-4682	91	10	of	of	ADP
fnp-4682	91	11	life	life	NOUN
fnp-4682	91	12	with	with	ADP
fnp-4682	91	13	spinal	spinal	ADJ
fnp-4682	91	14	rigidity	rigidity	NOUN
fnp-4682	91	15	and	and	CCONJ
fnp-4682	91	16	severe	severe	ADJ
fnp-4682	91	17	diaphragmatic	diaphragmatic	ADJ
fnp-4682	91	18	weakness	weakness	NOUN
fnp-4682	91	19	that	that	PRON
fnp-4682	91	20	led	lead	VERB
fnp-4682	91	21	to	to	ADP
fnp-4682	91	22	early	early	ADJ
fnp-4682	91	23	-	-	PUNCT
fnp-4682	91	24	onset	onset	NOUN
fnp-4682	91	25	respiratory	respiratory	ADJ
fnp-4682	91	26	failure	failure	NOUN
fnp-4682	91	27	.	.	PUNCT
fnp-4682	92	1	in	in	ADP
fnp-4682	92	2	contrast	contrast	NOUN
fnp-4682	92	3	,	,	PUNCT
fnp-4682	92	4	inoue	inoue	NOUN
fnp-4682	92	5	and	and	CCONJ
fnp-4682	92	6	colleagues	colleague	NOUN
fnp-4682	92	7	used	use	VERB
fnp-4682	92	8	a	a	DET
fnp-4682	92	9	more	more	ADV
fnp-4682	92	10	traditional	traditional	ADJ
fnp-4682	92	11	forward	forward	ADJ
fnp-4682	92	12	genetic	genetic	ADJ
fnp-4682	92	13	approach	approach	NOUN
fnp-4682	92	14	:	:	PUNCT
fnp-4682	92	15	they	they	PRON
fnp-4682	92	16	identified	identify	VERB
fnp-4682	92	17	a	a	DET
fnp-4682	92	18	single	single	ADJ
fnp-4682	92	19	family	family	NOUN
fnp-4682	92	20	with	with	ADP
fnp-4682	92	21	an	an	DET
fnp-4682	92	22	autosomal	autosomal	ADJ
fnp-4682	92	23	dominant	dominant	ADJ
fnp-4682	92	24	,	,	PUNCT
fnp-4682	92	25	slowly	slowly	ADV
fnp-4682	92	26	progressive	progressive	ADJ
fnp-4682	92	27	myopathy	myopathy	ADJ
fnp-4682	92	28	characterized	characterize	VERB
fnp-4682	92	29	by	by	ADP
fnp-4682	92	30	onset	onset	NOUN
fnp-4682	92	31	in	in	ADP
fnp-4682	92	32	the	the	DET
fnp-4682	92	33	3rd	3rd	NOUN
fnp-4682	92	34	to	to	ADP
fnp-4682	92	35	5th	5th	ADJ
fnp-4682	92	36	decade	decade	NOUN
fnp-4682	92	37	,	,	PUNCT
fnp-4682	92	38	asymmetric	asymmetric	ADJ
fnp-4682	92	39	thumb	thumb	NOUN
fnp-4682	92	40	and	and	CCONJ
fnp-4682	92	41	grip	grip	NOUN
fnp-4682	92	42	weakness	weakness	NOUN
fnp-4682	92	43	,	,	PUNCT
fnp-4682	92	44	symmetric	symmetric	ADJ
fnp-4682	92	45	distal	distal	ADJ
fnp-4682	92	46	weakness	weakness	NOUN
fnp-4682	92	47	,	,	PUNCT
fnp-4682	92	48	respiratory	respiratory	ADJ
fnp-4682	92	49	failure	failure	NOUN
fnp-4682	92	50	,	,	PUNCT
fnp-4682	92	51	scoliosis	scoliosis	NOUN
fnp-4682	92	52	,	,	PUNCT
fnp-4682	92	53	and	and	CCONJ
fnp-4682	92	54	ultimately	ultimately	ADV
fnp-4682	92	55	loss	loss	NOUN
fnp-4682	92	56	of	of	ADP
fnp-4682	92	57	ambulation	ambulation	NOUN
fnp-4682	92	58	,	,	PUNCT
fnp-4682	92	59	and	and	CCONJ
fnp-4682	92	60	showed	show	VERB
fnp-4682	92	61	that	that	SCONJ
fnp-4682	92	62	a	a	DET
fnp-4682	92	63	heterozygous	heterozygous	ADJ
fnp-4682	92	64	missense	missense	NOUN
fnp-4682	92	65	variant	variant	NOUN
fnp-4682	92	66	of	of	ADP
fnp-4682	92	67	dnajb4	dnajb4	PROPN
fnp-4682	92	68	(	(	PUNCT
fnp-4682	92	69	c.270t	c.270t	NOUN
fnp-4682	92	70	>	>	X
fnp-4682	92	71	a	a	PRON
fnp-4682	92	72	;	;	PUNCT
fnp-4682	92	73	p.phe90leu	p.phe90leu	NOUN
fnp-4682	92	74	)	)	PUNCT
fnp-4682	92	75	segregated	segregate	VERB
fnp-4682	92	76	with	with	ADP
fnp-4682	92	77	this	this	DET
fnp-4682	92	78	clinical	clinical	ADJ
fnp-4682	92	79	phenotype	phenotype	NOUN
fnp-4682	92	80	.	.	PUNCT
fnp-4682	93	1	muscle	muscle	NOUN
fnp-4682	93	2	pathology	pathology	NOUN
fnp-4682	93	3	was	be	AUX
fnp-4682	93	4	similar	similar	ADJ
fnp-4682	93	5	in	in	ADP
fnp-4682	93	6	both	both	CCONJ
fnp-4682	93	7	ad	ad	NOUN
fnp-4682	93	8	and	and	CCONJ
fnp-4682	93	9	ar	ar	NOUN
fnp-4682	93	10	forms	form	NOUN
fnp-4682	93	11	of	of	ADP
fnp-4682	93	12	dnajb4	dnajb4	ADJ
fnp-4682	93	13	disease	disease	NOUN
fnp-4682	93	14	,	,	PUNCT
fnp-4682	93	15	with	with	SCONJ
fnp-4682	93	16	fiber	fiber	NOUN
fnp-4682	93	17	size	size	NOUN
fnp-4682	93	18	variation	variation	NOUN
fnp-4682	93	19	,	,	PUNCT
fnp-4682	93	20	rubbed	rub	VERB
fnp-4682	93	21	out	out	ADP
fnp-4682	93	22	fiber	fiber	NOUN
fnp-4682	93	23	centers	center	NOUN
fnp-4682	93	24	on	on	ADP
fnp-4682	93	25	oxidative	oxidative	ADJ
fnp-4682	93	26	stains	stain	NOUN
fnp-4682	93	27	,	,	PUNCT
fnp-4682	93	28	rimmed	rim	VERB
fnp-4682	93	29	vacuoles	vacuole	NOUN
fnp-4682	93	30	in	in	ADP
fnp-4682	93	31	atrophic	atrophic	ADJ
fnp-4682	93	32	fibers	fiber	NOUN
fnp-4682	93	33	,	,	PUNCT
fnp-4682	93	34	and	and	CCONJ
fnp-4682	93	35	very	very	ADV
fnp-4682	93	36	large	large	ADJ
fnp-4682	93	37	central	central	ADJ
fnp-4682	93	38	inclusions	inclusion	NOUN
fnp-4682	93	39	/	/	SYM
fnp-4682	93	40	protein	protein	NOUN
fnp-4682	93	41	aggregates	aggregate	NOUN
fnp-4682	93	42	(	(	PUNCT
fnp-4682	93	43	up	up	ADP
fnp-4682	93	44	to	to	PART
fnp-4682	93	45	30	30	NUM
fnp-4682	93	46	-	-	SYM
fnp-4682	93	47	40	40	NUM
fnp-4682	93	48	sarcomeres	sarcomere	NOUN
fnp-4682	93	49	in	in	ADP
fnp-4682	93	50	length	length	NOUN
fnp-4682	93	51	)	)	PUNCT
fnp-4682	93	52	in	in	ADP
fnp-4682	93	53	non	non	ADJ
fnp-4682	93	54	-	-	ADJ
fnp-4682	93	55	atrophic	atrophic	ADJ
fnp-4682	93	56	fibers	fiber	NOUN
fnp-4682	93	57	that	that	PRON
fnp-4682	93	58	stained	stain	VERB
fnp-4682	93	59	red	red	NOUN
fnp-4682	93	60	on	on	ADP
fnp-4682	93	61	modified	modify	VERB
fnp-4682	93	62	gomori	gomori	PROPN
fnp-4682	93	63	trichrome	trichrome	PROPN
fnp-4682	93	64	,	,	PUNCT
fnp-4682	93	65	had	have	VERB
fnp-4682	93	66	an	an	DET
fnp-4682	93	67	amorphous	amorphous	ADJ
fnp-4682	93	68	“	"	PUNCT
fnp-4682	93	69	woolly	woolly	NOUN
fnp-4682	93	70	”	"	PUNCT
fnp-4682	93	71	or	or	CCONJ
fnp-4682	93	72	granulofilamentous	granulofilamentous	ADJ
fnp-4682	93	73	appearance	appearance	NOUN
fnp-4682	93	74	on	on	ADP
fnp-4682	93	75	em	em	PRON
fnp-4682	93	76	,	,	PUNCT
fnp-4682	93	77	and	and	CCONJ
fnp-4682	93	78	were	be	AUX
fnp-4682	93	79	immunopositive	immunopositive	ADJ
fnp-4682	93	80	positive	positive	ADJ
fnp-4682	93	81	for	for	ADP
fnp-4682	93	82	p62	p62	NOUN
fnp-4682	93	83	,	,	PUNCT
fnp-4682	93	84	hsp70	hsp70	NOUN
fnp-4682	93	85	,	,	PUNCT
fnp-4682	93	86	desmin	desmin	ADJ
fnp-4682	93	87	,	,	PUNCT
fnp-4682	93	88	myotilin	myotilin	NOUN
fnp-4682	93	89	,	,	PUNCT
fnp-4682	93	90	filamin	filamin	NOUN
fnp-4682	93	91	c	c	NOUN
fnp-4682	93	92	,	,	PUNCT
fnp-4682	93	93	and	and	CCONJ
fnp-4682	93	94	(	(	PUNCT
fnp-4682	93	95	in	in	ADP
fnp-4682	93	96	the	the	DET
fnp-4682	93	97	ad	ad	NOUN
fnp-4682	93	98	form	form	NOUN
fnp-4682	93	99	of	of	ADP
fnp-4682	93	100	disease	disease	NOUN
fnp-4682	93	101	)	)	PUNCT
fnp-4682	93	102	for	for	ADP
fnp-4682	93	103	dnajb4	dnajb4	PROPN
fnp-4682	93	104	.	.	PUNCT
fnp-4682	94	1	ultrastructurally	ultrastructurally	ADV
fnp-4682	94	2	,	,	PUNCT
fnp-4682	94	3	there	there	PRON
fnp-4682	94	4	was	be	VERB
fnp-4682	94	5	also	also	ADV
fnp-4682	94	6	widespread	widespread	ADJ
fnp-4682	94	7	degeneration	degeneration	NOUN
fnp-4682	94	8	of	of	ADP
fnp-4682	94	9	sarcomeres	sarcomere	NOUN
fnp-4682	94	10	,	,	PUNCT
fnp-4682	94	11	but	but	CCONJ
fnp-4682	94	12	z	z	X
fnp-4682	94	13	-	-	PUNCT
fnp-4682	94	14	discs	disc	NOUN
fnp-4682	94	15	were	be	AUX
fnp-4682	94	16	relatively	relatively	ADV
fnp-4682	94	17	spared	spare	VERB
fnp-4682	94	18	,	,	PUNCT
fnp-4682	94	19	with	with	ADP
fnp-4682	94	20	no	no	DET
fnp-4682	94	21	definite	definite	ADJ
fnp-4682	94	22	z	z	NOUN
fnp-4682	94	23	-	-	PUNCT
fnp-4682	94	24	band	band	NOUN
fnp-4682	94	25	widening	widening	NOUN
fnp-4682	94	26	or	or	CCONJ
fnp-4682	94	27	streaming	streaming	NOUN
fnp-4682	94	28	.	.	PUNCT
fnp-4682	95	1	interestingly	interestingly	ADV
fnp-4682	95	2	,	,	PUNCT
fnp-4682	95	3	inoue	inoue	PROPN
fnp-4682	95	4	and	and	CCONJ
fnp-4682	95	5	co	co	NOUN
fnp-4682	95	6	-	-	NOUN
fnp-4682	95	7	authors	author	NOUN
fnp-4682	95	8	showed	show	VERB
fnp-4682	95	9	that	that	SCONJ
fnp-4682	95	10	this	this	DET
fnp-4682	95	11	pathology	pathology	NOUN
fnp-4682	95	12	is	be	AUX
fnp-4682	95	13	more	more	ADV
fnp-4682	95	14	prominent	prominent	ADJ
fnp-4682	95	15	in	in	ADP
fnp-4682	95	16	type	type	NOUN
fnp-4682	95	17	1	1	NUM
fnp-4682	95	18	muscle	muscle	NOUN
fnp-4682	95	19	fibers	fiber	NOUN
fnp-4682	95	20	,	,	PUNCT
fnp-4682	95	21	providing	provide	VERB
fnp-4682	95	22	explanation	explanation	NOUN
fnp-4682	95	23	for	for	ADP
fnp-4682	95	24	the	the	DET
fnp-4682	95	25	preferential	preferential	ADJ
fnp-4682	95	26	clinical	clinical	ADJ
fnp-4682	95	27	involvement	involvement	NOUN
fnp-4682	95	28	of	of	ADP
fnp-4682	95	29	muscles	muscle	NOUN
fnp-4682	95	30	that	that	PRON
fnp-4682	95	31	are	be	AUX
fnp-4682	95	32	type	type	NOUN
fnp-4682	95	33	1	1	NUM
fnp-4682	95	34	fiber	fiber	NOUN
fnp-4682	95	35	-	-	PUNCT
fnp-4682	95	36	predominant	predominant	NOUN
fnp-4682	95	37	(	(	PUNCT
fnp-4682	95	38	soleus	soleus	NOUN
fnp-4682	95	39	,	,	PUNCT
fnp-4682	95	40	diaphragm	diaphragm	NOUN
fnp-4682	95	41	,	,	PUNCT
fnp-4682	95	42	paraspinals	paraspinal	NOUN
fnp-4682	95	43	,	,	PUNCT
fnp-4682	95	44	as	as	ADV
fnp-4682	95	45	well	well	ADV
fnp-4682	95	46	as	as	ADP
fnp-4682	95	47	thenar	thenar	ADJ
fnp-4682	95	48	and	and	CCONJ
fnp-4682	95	49	hypothenar	hypothenar	ADJ
fnp-4682	95	50	muscles	muscle	NOUN
fnp-4682	95	51	)	)	PUNCT
fnp-4682	95	52	.	.	PUNCT
fnp-4682	96	1	impressively	impressively	ADV
fnp-4682	96	2	,	,	PUNCT
fnp-4682	96	3	both	both	DET
fnp-4682	96	4	groups	group	NOUN
fnp-4682	96	5	generated	generate	VERB
fnp-4682	96	6	model	model	NOUN
fnp-4682	96	7	mice	mouse	NOUN
fnp-4682	96	8	that	that	PRON
fnp-4682	96	9	recapitulated	recapitulate	VERB
fnp-4682	96	10	key	key	ADJ
fnp-4682	96	11	aspects	aspect	NOUN
fnp-4682	96	12	of	of	ADP
fnp-4682	96	13	human	human	ADJ
fnp-4682	96	14	dnajb4	dnajb4	PROPN
fnp-4682	96	15	disease	disease	NOUN
fnp-4682	96	16	,	,	PUNCT
fnp-4682	96	17	including	include	VERB
fnp-4682	96	18	its	its	PRON
fnp-4682	96	19	unique	unique	ADJ
fnp-4682	96	20	myopathologic	myopathologic	NOUN
fnp-4682	96	21	features	feature	NOUN
fnp-4682	96	22	and	and	CCONJ
fnp-4682	96	23	preferential	preferential	ADJ
fnp-4682	96	24	involvement	involvement	NOUN
fnp-4682	96	25	of	of	ADP
fnp-4682	96	26	type	type	NOUN
fnp-4682	96	27	1	1	NUM
fnp-4682	96	28	muscle	muscle	NOUN
fnp-4682	96	29	fibers	fiber	NOUN
fnp-4682	96	30	;	;	PUNCT
fnp-4682	96	31	this	this	PRON
fnp-4682	96	32	was	be	AUX
fnp-4682	96	33	true	true	ADJ
fnp-4682	96	34	both	both	CCONJ
fnp-4682	96	35	for	for	ADP
fnp-4682	96	36	knockout	knockout	NOUN
fnp-4682	96	37	dnajb4-/mice	dnajb4-/mice	PROPN
fnp-4682	96	38	(	(	PUNCT
fnp-4682	96	39	which	which	DET
fnp-4682	96	40	model	model	NOUN
fnp-4682	96	41	ar	ar	PROPN
fnp-4682	96	42	human	human	PROPN
fnp-4682	96	43	disease	disease	PROPN
fnp-4682	96	44	;	;	PUNCT
fnp-4682	96	45	created	create	VERB
fnp-4682	96	46	independently	independently	ADV
fnp-4682	96	47	by	by	ADP
fnp-4682	96	48	both	both	DET
fnp-4682	96	49	groups	group	NOUN
fnp-4682	96	50	)	)	PUNCT
fnp-4682	96	51	and	and	CCONJ
fnp-4682	96	52	for	for	ADP
fnp-4682	96	53	dnajb4f90l/+	dnajb4f90l/+	PROPN
fnp-4682	96	54	knock	knock	VERB
fnp-4682	96	55	-	-	PUNCT
fnp-4682	96	56	in	in	ADP
fnp-4682	96	57	mice	mouse	NOUN
fnp-4682	96	58	(	(	PUNCT
fnp-4682	96	59	which	which	PRON
fnp-4682	96	60	model	model	VERB
fnp-4682	96	61	ad	ad	NOUN
fnp-4682	96	62	human	human	ADJ
fnp-4682	96	63	disease	disease	NOUN
fnp-4682	96	64	;	;	PUNCT
fnp-4682	96	65	created	create	VERB
fnp-4682	96	66	by	by	ADP
fnp-4682	96	67	inoue	inoue	PROPN
fnp-4682	96	68	et	et	PROPN
fnp-4682	96	69	al	al	PROPN
fnp-4682	96	70	.	.	PROPN
fnp-4682	96	71	)	)	PUNCT
fnp-4682	96	72	,	,	PUNCT
fnp-4682	96	73	suggesting	suggest	VERB
fnp-4682	96	74	that	that	SCONJ
fnp-4682	96	75	the	the	DET
fnp-4682	96	76	f90l	f90l	PROPN
fnp-4682	96	77	dnajb4	dnajb4	PROPN
fnp-4682	96	78	mutation	mutation	NOUN
fnp-4682	96	79	has	have	VERB
fnp-4682	96	80	a	a	DET
fnp-4682	96	81	dominant	dominant	ADJ
fnp-4682	96	82	negative	negative	ADJ
fnp-4682	96	83	effect	effect	NOUN
fnp-4682	96	84	.	.	PUNCT
fnp-4682	97	1	of	of	ADP
fnp-4682	97	2	course	course	NOUN
fnp-4682	97	3	,	,	PUNCT
fnp-4682	97	4	a	a	DET
fnp-4682	97	5	lot	lot	NOUN
fnp-4682	97	6	remains	remain	VERB
fnp-4682	97	7	to	to	PART
fnp-4682	97	8	be	be	AUX
fnp-4682	97	9	discovered	discover	VERB
fnp-4682	97	10	about	about	ADP
fnp-4682	97	11	this	this	DET
fnp-4682	97	12	new	new	ADJ
fnp-4682	97	13	disease	disease	NOUN
fnp-4682	97	14	.	.	PUNCT
fnp-4682	98	1	for	for	ADP
fnp-4682	98	2	example	example	NOUN
fnp-4682	98	3	,	,	PUNCT
fnp-4682	98	4	it	it	PRON
fnp-4682	98	5	remains	remain	VERB
fnp-4682	98	6	to	to	PART
fnp-4682	98	7	be	be	AUX
fnp-4682	98	8	established	establish	VERB
fnp-4682	98	9	why	why	SCONJ
fnp-4682	98	10	type	type	NOUN
fnp-4682	98	11	1	1	NUM
fnp-4682	98	12	muscle	muscle	NOUN
fnp-4682	98	13	fibers	fiber	NOUN
fnp-4682	98	14	are	be	AUX
fnp-4682	98	15	more	more	ADV
fnp-4682	98	16	vulnerable	vulnerable	ADJ
fnp-4682	98	17	to	to	ADP
fnp-4682	98	18	dnajb4	dnajb4	ADJ
fnp-4682	98	19	deficiency	deficiency	NOUN
fnp-4682	98	20	than	than	ADP
fnp-4682	98	21	type	type	NOUN
fnp-4682	98	22	2	2	NUM
fnp-4682	98	23	fibers	fiber	NOUN
fnp-4682	98	24	.	.	PUNCT
fnp-4682	99	1	in	in	ADP
fnp-4682	99	2	addition	addition	NOUN
fnp-4682	99	3	,	,	PUNCT
fnp-4682	99	4	it	it	PRON
fnp-4682	99	5	is	be	AUX
fnp-4682	99	6	not	not	PART
fnp-4682	99	7	entirely	entirely	ADV
fnp-4682	99	8	clear	clear	ADJ
fnp-4682	99	9	why	why	SCONJ
fnp-4682	99	10	there	there	PRON
fnp-4682	99	11	are	be	VERB
fnp-4682	99	12	significant	significant	ADJ
fnp-4682	99	13	clinicopathologic	clinicopathologic	ADJ
fnp-4682	99	14	differences	difference	NOUN
fnp-4682	99	15	between	between	ADP
fnp-4682	99	16	dnajb6	dnajb6	NOUN
fnp-4682	99	17	and	and	CCONJ
fnp-4682	99	18	dnajb4	dnajb4	ADJ
fnp-4682	99	19	diseases	disease	NOUN
fnp-4682	99	20	given	give	VERB
fnp-4682	99	21	the	the	DET
fnp-4682	99	22	large	large	ADJ
fnp-4682	99	23	degree	degree	NOUN
fnp-4682	99	24	of	of	ADP
fnp-4682	99	25	structural	structural	ADJ
fnp-4682	99	26	homology	homology	NOUN
fnp-4682	99	27	between	between	ADP
fnp-4682	99	28	these	these	DET
fnp-4682	99	29	two	two	NUM
fnp-4682	99	30	proteins	protein	NOUN
fnp-4682	99	31	.	.	PUNCT
fnp-4682	100	1	one	one	NUM
fnp-4682	100	2	clue	clue	NOUN
fnp-4682	100	3	that	that	PRON
fnp-4682	100	4	has	have	AUX
fnp-4682	100	5	emerged	emerge	VERB
fnp-4682	100	6	from	from	ADP
fnp-4682	100	7	the	the	DET
fnp-4682	100	8	work	work	NOUN
fnp-4682	100	9	of	of	ADP
fnp-4682	100	10	inoue	inoue	PROPN
fnp-4682	100	11	et	et	PROPN
fnp-4682	100	12	al	al	PROPN
fnp-4682	100	13	.	.	PROPN
fnp-4682	100	14	is	be	AUX
fnp-4682	100	15	a	a	DET
fnp-4682	100	16	subtle	subtle	ADJ
fnp-4682	100	17	difference	difference	NOUN
fnp-4682	100	18	in	in	ADP
fnp-4682	100	19	the	the	DET
fnp-4682	100	20	subcellular	subcellular	ADJ
fnp-4682	100	21	localization	localization	NOUN
fnp-4682	100	22	of	of	ADP
fnp-4682	100	23	these	these	DET
fnp-4682	100	24	two	two	NUM
fnp-4682	100	25	proteins	protein	NOUN
fnp-4682	100	26	:	:	PUNCT
fnp-4682	100	27	while	while	SCONJ
fnp-4682	100	28	dnajb4	dnajb4	PROPN
fnp-4682	100	29	is	be	AUX
fnp-4682	100	30	localized	localize	VERB
fnp-4682	100	31	to	to	ADP
fnp-4682	100	32	the	the	DET
fnp-4682	100	33	close	close	ADJ
fnp-4682	100	34	vicinity	vicinity	NOUN
fnp-4682	100	35	of	of	ADP
fnp-4682	100	36	the	the	DET
fnp-4682	100	37	z	z	NOUN
fnp-4682	100	38	-	-	PUNCT
fnp-4682	100	39	disc	disc	NOUN
fnp-4682	100	40	,	,	PUNCT
fnp-4682	100	41	dnajb6	dnajb6	NOUN
fnp-4682	100	42	directly	directly	ADV
fnp-4682	100	43	colocalizes	colocalize	VERB
fnp-4682	100	44	with	with	ADP
fnp-4682	100	45	this	this	DET
fnp-4682	100	46	structure	structure	NOUN
fnp-4682	100	47	.	.	PUNCT
fnp-4682	101	1	future	future	ADJ
fnp-4682	101	2	studies	study	NOUN
fnp-4682	101	3	will	will	AUX
fnp-4682	101	4	be	be	AUX
fnp-4682	101	5	necessary	necessary	ADJ
fnp-4682	101	6	to	to	PART
fnp-4682	101	7	delineate	delineate	VERB
fnp-4682	101	8	the	the	DET
fnp-4682	101	9	functional	functional	ADJ
fnp-4682	101	10	differences	difference	NOUN
fnp-4682	101	11	between	between	ADP
fnp-4682	101	12	these	these	DET
fnp-4682	101	13	two	two	NUM
fnp-4682	101	14	co	co	NOUN
fnp-4682	101	15	-	-	NOUN
fnp-4682	101	16	chaperones	chaperone	NOUN
fnp-4682	101	17	,	,	PUNCT
fnp-4682	101	18	particularly	particularly	ADV
fnp-4682	101	19	with	with	ADP
fnp-4682	101	20	respect	respect	NOUN
fnp-4682	101	21	to	to	ADP
fnp-4682	101	22	their	their	PRON
fnp-4682	101	23	roles	role	NOUN
fnp-4682	101	24	in	in	ADP
fnp-4682	101	25	chaperone	chaperone	NOUN
fnp-4682	101	26	-	-	PUNCT
fnp-4682	101	27	assisted	assist	VERB
fnp-4682	101	28	selective	selective	ADJ
fnp-4682	101	29	autophagy	autophagy	NOUN
fnp-4682	101	30	,	,	PUNCT
fnp-4682	101	31	and	and	CCONJ
fnp-4682	101	32	in	in	ADP
fnp-4682	101	33	formation	formation	NOUN
fnp-4682	101	34	and/or	and/or	CCONJ
fnp-4682	101	35	degradation	degradation	NOUN
fnp-4682	101	36	of	of	ADP
fnp-4682	101	37	rna	rna	NOUN
fnp-4682	101	38	stress	stress	NOUN
fnp-4682	101	39	granules	granule	NOUN
fnp-4682	101	40	.	.	PUNCT
fnp-4682	102	1	4	4	X
fnp-4682	102	2	.	.	X
fnp-4682	102	3	nmnat2	nmnat2	NOUN
fnp-4682	102	4	-	-	PUNCT
fnp-4682	102	5	deficient	deficient	ADJ
fnp-4682	102	6	,	,	PUNCT
fnp-4682	102	7	sarm1	sarm1	NOUN
fnp-4682	102	8	-	-	PUNCT
fnp-4682	102	9	dependent	dependent	ADJ
fnp-4682	102	10	hereditary	hereditary	ADJ
fnp-4682	102	11	axonal	axonal	ADJ
fnp-4682	102	12	neuropathy	neuropathy	ADJ
fnp-4682	102	13	(	(	PUNCT
fnp-4682	102	14	“	"	PUNCT
fnp-4682	102	15	sarmopathy	sarmopathy	ADJ
fnp-4682	102	16	”	"	PUNCT
fnp-4682	102	17	)	)	PUNCT
fnp-4682	102	18	wallerian	wallerian	NOUN
fnp-4682	102	19	degeneration	degeneration	NOUN
fnp-4682	102	20	is	be	AUX
fnp-4682	102	21	a	a	DET
fnp-4682	102	22	highly	highly	ADV
fnp-4682	102	23	regulated	regulate	VERB
fnp-4682	102	24	,	,	PUNCT
fnp-4682	102	25	active	active	ADJ
fnp-4682	102	26	process	process	NOUN
fnp-4682	102	27	of	of	ADP
fnp-4682	102	28	axon	axon	ADJ
fnp-4682	102	29	destruction	destruction	NOUN
fnp-4682	102	30	;	;	PUNCT
fnp-4682	102	31	it	it	PRON
fnp-4682	102	32	is	be	AUX
fnp-4682	102	33	typically	typically	ADV
fnp-4682	102	34	seen	see	VERB
fnp-4682	102	35	following	follow	VERB
fnp-4682	102	36	acute	acute	ADJ
fnp-4682	102	37	mechanical	mechanical	ADJ
fnp-4682	102	38	or	or	CCONJ
fnp-4682	102	39	ischemic	ischemic	ADJ
fnp-4682	102	40	injury	injury	NOUN
fnp-4682	102	41	,	,	PUNCT
fnp-4682	102	42	but	but	CCONJ
fnp-4682	102	43	can	can	AUX
fnp-4682	102	44	also	also	ADV
fnp-4682	102	45	be	be	AUX
fnp-4682	102	46	caused	cause	VERB
fnp-4682	102	47	by	by	ADP
fnp-4682	102	48	toxins	toxin	NOUN
fnp-4682	102	49	,	,	PUNCT
fnp-4682	102	50	nutritional	nutritional	ADJ
fnp-4682	102	51	deficiencies	deficiency	NOUN
fnp-4682	102	52	,	,	PUNCT
fnp-4682	102	53	immune	immune	NOUN
fnp-4682	102	54	-	-	PUNCT
fnp-4682	102	55	mediated	mediate	VERB
fnp-4682	102	56	injury	injury	NOUN
fnp-4682	102	57	(	(	PUNCT
fnp-4682	102	58	further	far	ADV
fnp-4682	102	59	discussed	discuss	VERB
fnp-4682	102	60	in	in	ADP
fnp-4682	102	61	advance	advance	NOUN
fnp-4682	102	62	#	#	SYM
fnp-4682	102	63	5	5	NUM
fnp-4682	102	64	)	)	PUNCT
fnp-4682	102	65	,	,	PUNCT
fnp-4682	102	66	and	and	CCONJ
fnp-4682	102	67	genetic	genetic	ADJ
fnp-4682	102	68	alterations	alteration	NOUN
fnp-4682	102	69	.	.	PUNCT
fnp-4682	103	1	regardless	regardless	ADV
fnp-4682	103	2	of	of	ADP
fnp-4682	103	3	the	the	DET
fnp-4682	103	4	underlying	underlie	VERB
fnp-4682	103	5	etiology	etiology	NOUN
fnp-4682	103	6	,	,	PUNCT
fnp-4682	103	7	wallerian	wallerian	ADJ
fnp-4682	103	8	degeneration	degeneration	NOUN
fnp-4682	103	9	is	be	AUX
fnp-4682	103	10	triggered	trigger	VERB
fnp-4682	103	11	by	by	ADP
fnp-4682	103	12	nad+	nad+	NOUN
fnp-4682	103	13	hydrolase	hydrolase	NOUN
fnp-4682	103	14	sarm1	sarm1	PROPN
fnp-4682	104	1	(	(	PUNCT
fnp-4682	104	2	sterile	sterile	ADJ
fnp-4682	104	3	alpha	alpha	NOUN
fnp-4682	104	4	and	and	CCONJ
fnp-4682	104	5	toll	toll	NOUN
fnp-4682	104	6	/	/	SYM
fnp-4682	104	7	interleukin-1	interleukin-1	NOUN
fnp-4682	104	8	receptor	receptor	NOUN
fnp-4682	104	9	motif	motif	NOUN
fnp-4682	104	10	-	-	PUNCT
fnp-4682	104	11	containing	contain	VERB
fnp-4682	104	12	1	1	NUM
fnp-4682	104	13	)	)	PUNCT
fnp-4682	104	14	,	,	PUNCT
fnp-4682	104	15	the	the	DET
fnp-4682	104	16	activity	activity	NOUN
fnp-4682	104	17	of	of	ADP
fnp-4682	104	18	which	which	PRON
fnp-4682	104	19	is	be	AUX
fnp-4682	104	20	regulated	regulate	VERB
fnp-4682	104	21	by	by	ADP
fnp-4682	104	22	the	the	DET
fnp-4682	104	23	axonal	axonal	ADJ
fnp-4682	104	24	nmn	nmn	PROPN
fnp-4682	104	25	/	/	SYM
fnp-4682	104	26	nad+	nad+	PROPN
fnp-4682	104	27	ratio	ratio	NOUN
fnp-4682	104	28	(	(	PUNCT
fnp-4682	104	29	osterloh	osterloh	PROPN
fnp-4682	104	30	et	et	PROPN
fnp-4682	104	31	al	al	PROPN
fnp-4682	104	32	.	.	PROPN
fnp-4682	104	33	,	,	PUNCT
fnp-4682	104	34	2012	2012	NUM
fnp-4682	104	35	;	;	PUNCT
fnp-4682	104	36	figley	figley	NOUN
fnp-4682	104	37	et	et	PROPN
fnp-4682	104	38	al	al	PROPN
fnp-4682	104	39	.	.	PROPN
fnp-4682	104	40	,	,	PUNCT
fnp-4682	104	41	2021	2021	NUM
fnp-4682	104	42	)	)	PUNCT
fnp-4682	104	43	.	.	PUNCT
fnp-4682	105	1	under	under	ADP
fnp-4682	105	2	normal	normal	ADJ
fnp-4682	105	3	conditions	condition	NOUN
fnp-4682	105	4	,	,	PUNCT
fnp-4682	105	5	the	the	DET
fnp-4682	105	6	activity	activity	NOUN
fnp-4682	105	7	of	of	ADP
fnp-4682	105	8	sarm1	sarm1	PROPN
fnp-4682	105	9	(	(	PUNCT
fnp-4682	105	10	which	which	PRON
fnp-4682	105	11	is	be	AUX
fnp-4682	105	12	often	often	ADV
fnp-4682	105	13	described	describe	VERB
fnp-4682	105	14	as	as	ADP
fnp-4682	105	15	“	"	PUNCT
fnp-4682	105	16	the	the	DET
fnp-4682	105	17	central	central	ADJ
fnp-4682	105	18	executioner	executioner	NOUN
fnp-4682	105	19	of	of	ADP
fnp-4682	105	20	a	a	DET
fnp-4682	105	21	cell	cell	NOUN
fnp-4682	105	22	-	-	PUNCT
fnp-4682	105	23	autonomous	autonomous	ADJ
fnp-4682	105	24	axon	axon	NOUN
fnp-4682	105	25	degeneration	degeneration	NOUN
fnp-4682	105	26	program	program	NOUN
fnp-4682	105	27	”	"	PUNCT
fnp-4682	105	28	)	)	PUNCT
fnp-4682	105	29	is	be	AUX
fnp-4682	105	30	kept	keep	VERB
fnp-4682	105	31	in	in	ADP
fnp-4682	105	32	check	check	NOUN
fnp-4682	105	33	by	by	ADP
fnp-4682	105	34	a	a	DET
fnp-4682	105	35	highly	highly	ADV
fnp-4682	105	36	labile	labile	ADJ
fnp-4682	105	37	nad+-generating	nad+-generate	VERB
fnp-4682	105	38	enzyme	enzyme	NOUN
fnp-4682	105	39	nmnat2	nmnat2	NOUN
fnp-4682	105	40	(	(	PUNCT
fnp-4682	105	41	nicotinamide	nicotinamide	NOUN
fnp-4682	105	42	mononucleotide	mononucleotide	NOUN
fnp-4682	105	43	adenylyltransferase	adenylyltransferase	ADJ
fnp-4682	105	44	2	2	NUM
fnp-4682	105	45	)	)	PUNCT
fnp-4682	105	46	;	;	PUNCT
fnp-4682	105	47	nmnat2	nmnat2	NOUN
fnp-4682	105	48	is	be	AUX
fnp-4682	105	49	trafficked	traffic	VERB
fnp-4682	105	50	from	from	ADP
fnp-4682	105	51	the	the	DET
fnp-4682	105	52	soma	soma	NOUN
fnp-4682	105	53	into	into	ADP
fnp-4682	105	54	the	the	DET
fnp-4682	105	55	axon	axon	NOUN
fnp-4682	105	56	,	,	PUNCT
fnp-4682	105	57	where	where	SCONJ
fnp-4682	105	58	it	it	PRON
fnp-4682	105	59	catalyzes	catalyze	VERB
fnp-4682	105	60	synthesis	synthesis	NOUN
fnp-4682	105	61	of	of	ADP
fnp-4682	105	62	nad+	nad+	PROPN
fnp-4682	105	63	using	use	VERB
fnp-4682	105	64	nmn	nmn	PROPN
fnp-4682	105	65	and	and	CCONJ
fnp-4682	105	66	atp	atp	PROPN
fnp-4682	105	67	as	as	ADP
fnp-4682	105	68	substrates	substrate	NOUN
fnp-4682	105	69	(	(	PUNCT
fnp-4682	105	70	conforti	conforti	PROPN
fnp-4682	105	71	et	et	PROPN
fnp-4682	105	72	al	al	PROPN
fnp-4682	105	73	.	.	PROPN
fnp-4682	105	74	,	,	PUNCT
fnp-4682	105	75	2014	2014	NUM
fnp-4682	105	76	)	)	PUNCT
fnp-4682	105	77	.	.	PUNCT
fnp-4682	106	1	axonal	axonal	ADJ
fnp-4682	106	2	injury	injury	NOUN
fnp-4682	106	3	disrupts	disrupt	VERB
fnp-4682	106	4	axon	axon	NOUN
fnp-4682	106	5	transport	transport	NOUN
fnp-4682	106	6	of	of	ADP
fnp-4682	106	7	nmnat2	nmnat2	NOUN
fnp-4682	106	8	,	,	PUNCT
fnp-4682	106	9	resulting	result	VERB
fnp-4682	106	10	in	in	ADP
fnp-4682	106	11	the	the	DET
fnp-4682	106	12	buildup	buildup	NOUN
fnp-4682	106	13	of	of	ADP
fnp-4682	106	14	nmn	nmn	PROPN
fnp-4682	106	15	and	and	CCONJ
fnp-4682	106	16	depletion	depletion	NOUN
fnp-4682	106	17	of	of	ADP
fnp-4682	106	18	nad+	nad+	PROPN
fnp-4682	106	19	distal	distal	NOUN
fnp-4682	106	20	to	to	ADP
fnp-4682	106	21	the	the	DET
fnp-4682	106	22	injury	injury	NOUN
fnp-4682	106	23	site	site	NOUN
fnp-4682	106	24	;	;	PUNCT
fnp-4682	106	25	this	this	PRON
fnp-4682	106	26	increases	increase	VERB
fnp-4682	106	27	the	the	DET
fnp-4682	106	28	nmn	nmn	PROPN
fnp-4682	106	29	/	/	SYM
fnp-4682	106	30	nad+	nad+	PROPN
fnp-4682	106	31	ratio	ratio	NOUN
fnp-4682	106	32	and	and	CCONJ
fnp-4682	106	33	activates	activate	VERB
fnp-4682	106	34	sarm1	sarm1	PROPN
fnp-4682	106	35	,	,	PUNCT
fnp-4682	106	36	further	far	ADV
fnp-4682	106	37	depleting	deplete	VERB
fnp-4682	106	38	nad+	nad+	PROPN
fnp-4682	106	39	levels	level	NOUN
fnp-4682	106	40	and	and	CCONJ
fnp-4682	106	41	causing	cause	VERB
fnp-4682	106	42	metabolic	metabolic	NOUN
fnp-4682	106	43	crisis	crisis	NOUN
fnp-4682	106	44	that	that	PRON
fnp-4682	106	45	ultimately	ultimately	ADV
fnp-4682	106	46	leads	lead	VERB
fnp-4682	106	47	to	to	ADP
fnp-4682	106	48	axon	axon	VERB
fnp-4682	106	49	fragmentation	fragmentation	NOUN
fnp-4682	106	50	.	.	PUNCT
fnp-4682	107	1	not	not	PART
fnp-4682	107	2	surprisingly	surprisingly	ADV
fnp-4682	107	3	,	,	PUNCT
fnp-4682	107	4	deletion	deletion	NOUN
fnp-4682	107	5	of	of	ADP
fnp-4682	107	6	nmnat2	nmnat2	NOUN
fnp-4682	107	7	in	in	ADP
fnp-4682	107	8	mouse	mouse	NOUN
fnp-4682	107	9	models	model	NOUN
fnp-4682	107	10	leads	lead	VERB
fnp-4682	107	11	to	to	ADP
fnp-4682	107	12	perinatal	perinatal	ADJ
fnp-4682	107	13	lethality	lethality	NOUN
fnp-4682	107	14	;	;	PUNCT
fnp-4682	107	15	however	however	ADV
fnp-4682	107	16	,	,	PUNCT
fnp-4682	107	17	mice	mouse	NOUN
fnp-4682	107	18	lacking	lack	VERB
fnp-4682	107	19	both	both	DET
fnp-4682	107	20	nmnat2	nmnat2	NOUN
fnp-4682	107	21	and	and	CCONJ
fnp-4682	107	22	sarm1	sarm1	NOUN
fnp-4682	107	23	are	be	AUX
fnp-4682	107	24	viable	viable	ADJ
fnp-4682	107	25	and	and	CCONJ
fnp-4682	107	26	protected	protect	VERB
fnp-4682	107	27	against	against	ADP
fnp-4682	107	28	axonal	axonal	ADJ
fnp-4682	107	29	degeneration	degeneration	NOUN
fnp-4682	107	30	.	.	PUNCT
fnp-4682	108	1	in	in	ADP
fnp-4682	108	2	humans	human	NOUN
fnp-4682	108	3	,	,	PUNCT
fnp-4682	108	4	nmnat2	nmnat2	NOUN
fnp-4682	108	5	deficiency	deficiency	NOUN
fnp-4682	108	6	is	be	AUX
fnp-4682	108	7	very	very	ADV
fnp-4682	108	8	rare	rare	ADJ
fnp-4682	108	9	;	;	PUNCT
fnp-4682	108	10	however	however	ADV
fnp-4682	108	11	,	,	PUNCT
fnp-4682	108	12	homozygous	homozygous	ADJ
fnp-4682	108	13	r232q	r232q	PROPN
fnp-4682	108	14	nmnat2	nmnat2	NOUN
fnp-4682	108	15	variant	variant	NOUN
fnp-4682	108	16	(	(	PUNCT
fnp-4682	108	17	which	which	PRON
fnp-4682	108	18	causes	cause	VERB
fnp-4682	108	19	severe	severe	ADJ
fnp-4682	108	20	reduction	reduction	NOUN
fnp-4682	108	21	in	in	ADP
fnp-4682	108	22	nmnat2	nmnat2	NOUN
fnp-4682	108	23	activity	activity	NOUN
fnp-4682	108	24	)	)	PUNCT
fnp-4682	108	25	has	have	AUX
fnp-4682	108	26	been	be	AUX
fnp-4682	108	27	linked	link	VERB
fnp-4682	108	28	to	to	PART
fnp-4682	108	29	fetal	fetal	VERB
fnp-4682	108	30	akinesia	akinesia	ADJ
fnp-4682	108	31	deformation	deformation	NOUN
fnp-4682	108	32	sequence	sequence	NOUN
fnp-4682	108	33	(	(	PUNCT
fnp-4682	108	34	lukacs	lukacs	PROPN
fnp-4682	108	35	et	et	PROPN
fnp-4682	108	36	al	al	PROPN
fnp-4682	108	37	.	.	PROPN
fnp-4682	108	38	,	,	PUNCT
fnp-4682	108	39	2019	2019	NUM
fnp-4682	108	40	)	)	PUNCT
fnp-4682	108	41	,	,	PUNCT
fnp-4682	108	42	while	while	SCONJ
fnp-4682	108	43	homozygous	homozygous	ADJ
fnp-4682	108	44	t94	t94	NOUN
fnp-4682	108	45	m	m	NOUN
fnp-4682	108	46	nmnat2	nmnat2	NOUN
fnp-4682	108	47	variant	variant	NOUN
fnp-4682	108	48	(	(	PUNCT
fnp-4682	108	49	which	which	PRON
fnp-4682	108	50	reduces	reduce	VERB
fnp-4682	108	51	nmnat2	nmnat2	NOUN
fnp-4682	108	52	thermal	thermal	ADJ
fnp-4682	108	53	stability	stability	NOUN
fnp-4682	108	54	)	)	PUNCT
fnp-4682	108	55	causes	cause	VERB
fnp-4682	108	56	mild	mild	ADJ
fnp-4682	108	57	sensorimotor	sensorimotor	NOUN
fnp-4682	108	58	axonal	axonal	ADJ
fnp-4682	108	59	polyneuropathy	polyneuropathy	NOUN
fnp-4682	108	60	with	with	ADP
fnp-4682	108	61	erythromelalgia	erythromelalgia	NOUN
fnp-4682	108	62	(	(	PUNCT
fnp-4682	108	63	huppke	huppke	NOUN
fnp-4682	108	64	et	et	PROPN
fnp-4682	108	65	al	al	PROPN
fnp-4682	108	66	.	.	PROPN
fnp-4682	108	67	,	,	PUNCT
fnp-4682	108	68	2019	2019	NUM
fnp-4682	108	69	)	)	PUNCT
fnp-4682	108	70	.	.	PUNCT
fnp-4682	109	1	(	(	PUNCT
fnp-4682	109	2	erythromelalgia	erythromelalgia	NOUN
fnp-4682	109	3	is	be	AUX
fnp-4682	109	4	a	a	DET
fnp-4682	109	5	syndrome	syndrome	NOUN
fnp-4682	109	6	that	that	PRON
fnp-4682	109	7	consists	consist	VERB
fnp-4682	109	8	of	of	ADP
fnp-4682	109	9	sporadic	sporadic	ADJ
fnp-4682	109	10	attacks	attack	NOUN
fnp-4682	109	11	of	of	ADP
fnp-4682	109	12	burning	burn	VERB
fnp-4682	109	13	pain	pain	NOUN
fnp-4682	109	14	,	,	PUNCT
fnp-4682	109	15	redness	redness	NOUN
fnp-4682	109	16	,	,	PUNCT
fnp-4682	109	17	and	and	CCONJ
fnp-4682	109	18	swelling	swell	VERB
fnp-4682	109	19	,	,	PUNCT
fnp-4682	109	20	typically	typically	ADV
fnp-4682	109	21	affecting	affect	VERB
fnp-4682	109	22	the	the	DET
fnp-4682	109	23	lower	low	ADJ
fnp-4682	109	24	extremities	extremity	NOUN
fnp-4682	109	25	;	;	PUNCT
fnp-4682	109	26	it	it	PRON
fnp-4682	109	27	is	be	AUX
fnp-4682	109	28	most	most	ADV
fnp-4682	109	29	often	often	ADV
fnp-4682	109	30	caused	cause	VERB
fnp-4682	109	31	by	by	ADP
fnp-4682	109	32	gain	gain	NOUN
fnp-4682	109	33	-	-	PUNCT
fnp-4682	109	34	of	of	ADP
fnp-4682	109	35	-	-	PUNCT
fnp-4682	109	36	function	function	NOUN
fnp-4682	109	37	mutations	mutation	NOUN
fnp-4682	109	38	in	in	ADP
fnp-4682	109	39	scn9a	scn9a	PROPN
fnp-4682	109	40	,	,	PUNCT
fnp-4682	109	41	which	which	PRON
fnp-4682	109	42	encodes	encode	VERB
fnp-4682	109	43	sodium	sodium	NOUN
fnp-4682	109	44	channel	channel	NOUN
fnp-4682	109	45	nav1.7	nav1.7	PROPN
fnp-4682	109	46	.	.	PUNCT
fnp-4682	109	47	)	)	PUNCT
fnp-4682	110	1	in	in	ADP
fnp-4682	110	2	their	their	PRON
fnp-4682	110	3	tour	tour	NOUN
fnp-4682	110	4	-	-	PUNCT
fnp-4682	110	5	de	de	ADJ
fnp-4682	110	6	-	-	NOUN
fnp-4682	110	7	force	force	NOUN
fnp-4682	110	8	study	study	NOUN
fnp-4682	110	9	published	publish	VERB
fnp-4682	110	10	last	last	ADJ
fnp-4682	110	11	year	year	NOUN
fnp-4682	110	12	,	,	PUNCT
fnp-4682	110	13	dingwall	dingwall	PROPN
fnp-4682	110	14	and	and	CCONJ
fnp-4682	110	15	coauthors	coauthor	NOUN
fnp-4682	110	16	expanded	expand	VERB
fnp-4682	110	17	the	the	DET
fnp-4682	110	18	spectrum	spectrum	NOUN
fnp-4682	110	19	of	of	ADP
fnp-4682	110	20	human	human	ADJ
fnp-4682	110	21	nmnat2	nmnat2	NOUN
fnp-4682	110	22	-	-	PUNCT
fnp-4682	110	23	associated	associate	VERB
fnp-4682	110	24	disease	disease	NOUN
fnp-4682	110	25	by	by	ADP
fnp-4682	110	26	showing	show	VERB
fnp-4682	110	27	that	that	SCONJ
fnp-4682	110	28	heterozygous	heterozygous	ADJ
fnp-4682	110	29	nmnat2	nmnat2	NOUN
fnp-4682	110	30	loss	loss	NOUN
fnp-4682	110	31	-	-	PUNCT
fnp-4682	110	32	of	of	ADP
fnp-4682	110	33	-	-	PUNCT
fnp-4682	110	34	function	function	NOUN
fnp-4682	110	35	mutations	mutation	NOUN
fnp-4682	110	36	cause	cause	VERB
fnp-4682	110	37	severe	severe	ADJ
fnp-4682	110	38	hereditary	hereditary	ADJ
fnp-4682	110	39	axonal	axonal	ADJ
fnp-4682	110	40	neuropathy	neuropathy	ADJ
fnp-4682	110	41	through	through	ADP
fnp-4682	110	42	a	a	DET
fnp-4682	110	43	sarm1	sarm1	NOUN
fnp-4682	110	44	-	-	PUNCT
fnp-4682	110	45	dependent	dependent	ADJ
fnp-4682	110	46	,	,	PUNCT
fnp-4682	110	47	macrophage	macrophage	NOUN
fnp-4682	110	48	-	-	PUNCT
fnp-4682	110	49	mediated	mediate	VERB
fnp-4682	110	50	non	non	ADJ
fnp-4682	110	51	-	-	ADJ
fnp-4682	110	52	cell	cell	ADJ
fnp-4682	110	53	autonomous	autonomous	ADJ
fnp-4682	110	54	pathway	pathway	NOUN
fnp-4682	110	55	;	;	PUNCT
fnp-4682	110	56	consequently	consequently	ADV
fnp-4682	110	57	,	,	PUNCT
fnp-4682	110	58	the	the	DET
fnp-4682	110	59	authors	author	NOUN
fnp-4682	110	60	have	have	AUX
fnp-4682	110	61	termed	term	VERB
fnp-4682	110	62	this	this	DET
fnp-4682	110	63	new	new	ADJ
fnp-4682	110	64	disease	disease	NOUN
fnp-4682	110	65	“	"	PUNCT
fnp-4682	110	66	sarmopathy	sarmopathy	ADJ
fnp-4682	110	67	”	"	PUNCT
fnp-4682	110	68	(	(	PUNCT
fnp-4682	110	69	dingwall	dingwall	PROPN
fnp-4682	110	70	et	et	PROPN
fnp-4682	110	71	al	al	PROPN
fnp-4682	110	72	.	.	PROPN
fnp-4682	110	73	,	,	PUNCT
fnp-4682	110	74	2022	2022	NUM
fnp-4682	110	75	)	)	PUNCT
fnp-4682	110	76	.	.	PUNCT
fnp-4682	111	1	the	the	DET
fnp-4682	111	2	two	two	NUM
fnp-4682	111	3	affected	affected	ADJ
fnp-4682	111	4	brothers	brother	NOUN
fnp-4682	111	5	described	describe	VERB
fnp-4682	111	6	by	by	ADP
fnp-4682	111	7	dingwall	dingwall	PROPN
fnp-4682	111	8	et	et	PROPN
fnp-4682	111	9	al	al	PROPN
fnp-4682	111	10	.	.	PROPN
fnp-4682	111	11	share	share	VERB
fnp-4682	111	12	a	a	DET
fnp-4682	111	13	very	very	ADV
fnp-4682	111	14	unique	unique	ADJ
fnp-4682	111	15	clinical	clinical	ADJ
fnp-4682	111	16	phenotype	phenotype	NOUN
fnp-4682	111	17	that	that	PRON
fnp-4682	111	18	includes	include	VERB
fnp-4682	111	19	(	(	PUNCT
fnp-4682	111	20	i	i	NOUN
fnp-4682	111	21	)	)	PUNCT
fnp-4682	111	22	repeated	repeat	VERB
fnp-4682	111	23	episodes	episode	NOUN
fnp-4682	111	24	of	of	ADP
fnp-4682	111	25	acute	acute	ADJ
fnp-4682	111	26	multifocal	multifocal	ADJ
fnp-4682	111	27	sensorimotor	sensorimotor	NOUN
fnp-4682	111	28	axonal	axonal	ADJ
fnp-4682	111	29	neuropathy	neuropathy	ADJ
fnp-4682	111	30	(	(	PUNCT
fnp-4682	111	31	amsan	amsan	NOUN
fnp-4682	111	32	)	)	PUNCT
fnp-4682	111	33	that	that	PRON
fnp-4682	111	34	mimic	mimic	ADJ
fnp-4682	111	35	guillain	guillain	NOUN
fnp-4682	111	36	-	-	PUNCT
fnp-4682	111	37	barré	barré	PROPN
fnp-4682	111	38	syndrome	syndrome	PROPN
fnp-4682	111	39	(	(	PUNCT
fnp-4682	111	40	gbs	gbs	PROPN
fnp-4682	111	41	)	)	PUNCT
fnp-4682	111	42	,	,	PUNCT
fnp-4682	111	43	are	be	AUX
fnp-4682	111	44	typically	typically	ADV
fnp-4682	111	45	triggered	trigger	VERB
fnp-4682	111	46	by	by	ADP
fnp-4682	111	47	acute	acute	ADJ
fnp-4682	111	48	infection	infection	NOUN
fnp-4682	111	49	,	,	PUNCT
fnp-4682	111	50	and	and	CCONJ
fnp-4682	111	51	include	include	VERB
fnp-4682	111	52	severe	severe	ADJ
fnp-4682	111	53	pain	pain	NOUN
fnp-4682	111	54	,	,	PUNCT
fnp-4682	111	55	erythromelalgia	erythromelalgia	NOUN
fnp-4682	111	56	,	,	PUNCT
fnp-4682	111	57	flaccid	flaccid	ADJ
fnp-4682	111	58	quadriparesis	quadriparesis	NOUN
fnp-4682	111	59	,	,	PUNCT
fnp-4682	111	60	and	and	CCONJ
fnp-4682	111	61	respiratory	respiratory	ADJ
fnp-4682	111	62	failure	failure	NOUN
fnp-4682	111	63	;	;	PUNCT
fnp-4682	111	64	and	and	CCONJ
fnp-4682	111	65	(	(	PUNCT
fnp-4682	111	66	ii	ii	NOUN
fnp-4682	111	67	)	)	PUNCT
fnp-4682	111	68	chronic	chronic	ADJ
fnp-4682	111	69	axonal	axonal	ADJ
fnp-4682	111	70	motor	motor	NOUN
fnp-4682	111	71	neuropathy	neuropathy	ADJ
fnp-4682	111	72	that	that	SCONJ
fnp-4682	111	73	progresses	progress	VERB
fnp-4682	111	74	between	between	ADP
fnp-4682	111	75	these	these	DET
fnp-4682	111	76	acute	acute	NOUN
fnp-4682	111	77	episodes	episode	NOUN
fnp-4682	111	78	and	and	CCONJ
fnp-4682	111	79	leads	lead	VERB
fnp-4682	111	80	to	to	ADP
fnp-4682	111	81	distal	distal	ADJ
fnp-4682	111	82	weakness	weakness	NOUN
fnp-4682	111	83	,	,	PUNCT
fnp-4682	111	84	scoliosis	scoliosis	NOUN
fnp-4682	111	85	,	,	PUNCT
fnp-4682	111	86	and	and	CCONJ
fnp-4682	111	87	wheelchair	wheelchair	NOUN
fnp-4682	111	88	dependence	dependence	NOUN
fnp-4682	111	89	in	in	ADP
fnp-4682	111	90	the	the	DET
fnp-4682	111	91	third	third	ADJ
fnp-4682	111	92	decade	decade	NOUN
fnp-4682	111	93	of	of	ADP
fnp-4682	111	94	life	life	NOUN
fnp-4682	111	95	.	.	PUNCT
fnp-4682	112	1	the	the	DET
fnp-4682	112	2	patients	patient	NOUN
fnp-4682	112	3	carry	carry	VERB
fnp-4682	112	4	compound	compound	ADV
fnp-4682	112	5	heterozygous	heterozygous	ADJ
fnp-4682	112	6	nmnat2	nmnat2	NOUN
fnp-4682	112	7	variants	variant	NOUN
fnp-4682	112	8	(	(	PUNCT
fnp-4682	112	9	the	the	DET
fnp-4682	112	10	previously	previously	ADV
fnp-4682	112	11	identified	identify	VERB
fnp-4682	112	12	pathogenic	pathogenic	ADJ
fnp-4682	112	13	variant	variant	NOUN
fnp-4682	112	14	c.695g	c.695g	PROPN
fnp-4682	112	15	>	>	X
fnp-4682	112	16	a	a	PRON
fnp-4682	112	17	;	;	PUNCT
fnp-4682	112	18	p.arg232gln	p.arg232gln	VERB
fnp-4682	112	19	/	/	SYM
fnp-4682	112	20	r232q	r232q	PROPN
fnp-4682	112	21	and	and	CCONJ
fnp-4682	112	22	a	a	DET
fnp-4682	112	23	novel	novel	ADJ
fnp-4682	112	24	variant	variant	NOUN
fnp-4682	112	25	c.292g	c.292g	NOUN
fnp-4682	112	26	>	>	X
fnp-4682	112	27	a	a	PRON
fnp-4682	112	28	;	;	PUNCT
fnp-4682	112	29	p.val98met	p.val98met	X
fnp-4682	112	30	/	/	SYM
fnp-4682	112	31	v98	v98	NOUN
fnp-4682	112	32	m	m	PROPN
fnp-4682	112	33	)	)	PUNCT
fnp-4682	112	34	;	;	PUNCT
fnp-4682	112	35	each	each	PRON
fnp-4682	112	36	of	of	ADP
fnp-4682	112	37	these	these	DET
fnp-4682	112	38	variants	variant	NOUN
fnp-4682	112	39	was	be	AUX
fnp-4682	112	40	inherited	inherit	VERB
fnp-4682	112	41	from	from	ADP
fnp-4682	112	42	one	one	NUM
fnp-4682	112	43	of	of	ADP
fnp-4682	112	44	the	the	DET
fnp-4682	112	45	patients	patient	NOUN
fnp-4682	112	46	’	'	PUNCT
fnp-4682	112	47	asymptomatic	asymptomatic	ADJ
fnp-4682	112	48	parents	parent	NOUN
fnp-4682	112	49	and	and	CCONJ
fnp-4682	112	50	was	be	AUX
fnp-4682	112	51	shown	show	VERB
fnp-4682	112	52	to	to	PART
fnp-4682	112	53	markedly	markedly	ADV
fnp-4682	112	54	reduce	reduce	VERB
fnp-4682	112	55	nmnat2	nmnat2	NOUN
fnp-4682	112	56	enzymatic	enzymatic	ADJ
fnp-4682	112	57	activity	activity	NOUN
fnp-4682	112	58	.	.	PUNCT
fnp-4682	113	1	to	to	PART
fnp-4682	113	2	further	far	ADV
fnp-4682	113	3	study	study	VERB
fnp-4682	113	4	this	this	DET
fnp-4682	113	5	new	new	ADJ
fnp-4682	113	6	hereditary	hereditary	NOUN
fnp-4682	113	7	neuropathy	neuropathy	ADJ
fnp-4682	113	8	,	,	PUNCT
fnp-4682	113	9	the	the	DET
fnp-4682	113	10	authors	author	NOUN
fnp-4682	113	11	generated	generate	VERB
fnp-4682	113	12	nmnat2v98m	nmnat2v98m	NOUN
fnp-4682	113	13	/	/	SYM
fnp-4682	113	14	r232q	r232q	PROPN
fnp-4682	113	15	model	model	NOUN
fnp-4682	113	16	mice	mouse	NOUN
fnp-4682	113	17	.	.	PUNCT
fnp-4682	114	1	like	like	ADP
fnp-4682	114	2	the	the	DET
fnp-4682	114	3	two	two	NUM
fnp-4682	114	4	patients	patient	NOUN
fnp-4682	114	5	,	,	PUNCT
fnp-4682	114	6	these	these	DET
fnp-4682	114	7	model	model	NOUN
fnp-4682	114	8	mice	mouse	NOUN
fnp-4682	114	9	developed	develop	VERB
fnp-4682	114	10	an	an	DET
fnp-4682	114	11	age	age	NOUN
fnp-4682	114	12	-	-	PUNCT
fnp-4682	114	13	dependent	dependent	ADJ
fnp-4682	114	14	,	,	PUNCT
fnp-4682	114	15	motor	motor	NOUN
fnp-4682	114	16	-	-	PUNCT
fnp-4682	114	17	predominant	predominant	ADJ
fnp-4682	114	18	axonal	axonal	ADJ
fnp-4682	114	19	polyneuropathy	polyneuropathy	NOUN
fnp-4682	114	20	that	that	PRON
fnp-4682	114	21	led	lead	VERB
fnp-4682	114	22	to	to	ADP
fnp-4682	114	23	severe	severe	ADJ
fnp-4682	114	24	hindlimb	hindlimb	NOUN
fnp-4682	114	25	wasting	waste	VERB
fnp-4682	114	26	by	by	ADP
fnp-4682	114	27	9	9	NUM
fnp-4682	114	28	-	-	SYM
fnp-4682	114	29	12	12	NUM
fnp-4682	114	30	months	month	NOUN
fnp-4682	114	31	of	of	ADP
fnp-4682	114	32	age	age	NOUN
fnp-4682	114	33	and	and	CCONJ
fnp-4682	114	34	was	be	AUX
fnp-4682	114	35	characterized	characterize	VERB
fnp-4682	114	36	by	by	ADP
fnp-4682	114	37	a	a	DET
fnp-4682	114	38	severe	severe	ADJ
fnp-4682	114	39	loss	loss	NOUN
fnp-4682	114	40	of	of	ADP
fnp-4682	114	41	axons	axon	NOUN
fnp-4682	114	42	in	in	ADP
fnp-4682	114	43	mixed	mixed	ADJ
fnp-4682	114	44	and	and	CCONJ
fnp-4682	114	45	motor	motor	NOUN
fnp-4682	114	46	nerves	nerve	NOUN
fnp-4682	114	47	(	(	PUNCT
fnp-4682	114	48	fig	fig	NOUN
fnp-4682	114	49	.	.	PUNCT
fnp-4682	115	1	3a	3a	NUM
fnp-4682	115	2	-	-	SYM
fnp-4682	115	3	b	b	NOUN
fnp-4682	115	4	)	)	PUNCT
fnp-4682	115	5	;	;	PUNCT
fnp-4682	115	6	in	in	ADP
fnp-4682	115	7	contrast	contrast	NOUN
fnp-4682	115	8	,	,	PUNCT
fnp-4682	115	9	sensory	sensory	ADJ
fnp-4682	115	10	nerves	nerve	NOUN
fnp-4682	115	11	were	be	AUX
fnp-4682	115	12	largely	largely	ADV
fnp-4682	115	13	spared	spare	VERB
fnp-4682	115	14	(	(	PUNCT
fnp-4682	115	15	fig	fig	NOUN
fnp-4682	115	16	.	.	PUNCT
fnp-4682	116	1	3c	3c	NUM
fnp-4682	116	2	)	)	PUNCT
fnp-4682	116	3	,	,	PUNCT
fnp-4682	116	4	as	as	SCONJ
fnp-4682	116	5	were	be	AUX
fnp-4682	116	6	motor	motor	PROPN
fnp-4682	116	7	neuron	neuron	NOUN
fnp-4682	116	8	cell	cell	NOUN
fnp-4682	116	9	bodies	body	NOUN
fnp-4682	116	10	in	in	ADP
fnp-4682	116	11	the	the	DET
fnp-4682	116	12	ventral	ventral	ADJ
fnp-4682	116	13	horn	horn	NOUN
fnp-4682	116	14	of	of	ADP
fnp-4682	116	15	the	the	DET
fnp-4682	116	16	spinal	spinal	ADJ
fnp-4682	116	17	cord	cord	NOUN
fnp-4682	116	18	.	.	PUNCT
fnp-4682	117	1	unlike	unlike	ADP
fnp-4682	117	2	the	the	DET
fnp-4682	117	3	two	two	NUM
fnp-4682	117	4	patients	patient	NOUN
fnp-4682	117	5	,	,	PUNCT
fnp-4682	117	6	the	the	DET
fnp-4682	117	7	model	model	NOUN
fnp-4682	117	8	mice	mouse	NOUN
fnp-4682	117	9	did	do	AUX
fnp-4682	117	10	not	not	PART
fnp-4682	117	11	develop	develop	VERB
fnp-4682	117	12	amsan	amsan	ADJ
fnp-4682	117	13	episodes	episode	NOUN
fnp-4682	117	14	or	or	CCONJ
fnp-4682	117	15	hypersensitivity	hypersensitivity	NOUN
fnp-4682	117	16	to	to	ADP
fnp-4682	117	17	pain	pain	NOUN
fnp-4682	117	18	,	,	PUNCT
fnp-4682	117	19	possibly	possibly	ADV
fnp-4682	117	20	because	because	SCONJ
fnp-4682	117	21	they	they	PRON
fnp-4682	117	22	were	be	AUX
fnp-4682	117	23	housed	house	VERB
fnp-4682	117	24	in	in	ADP
fnp-4682	117	25	a	a	DET
fnp-4682	117	26	pathogen	pathogen	NOUN
fnp-4682	117	27	-	-	PUNCT
fnp-4682	117	28	free	free	ADJ
fnp-4682	117	29	animal	animal	NOUN
fnp-4682	117	30	facility	facility	NOUN
fnp-4682	117	31	and	and	CCONJ
fnp-4682	117	32	thereby	thereby	ADV
fnp-4682	117	33	spared	spare	VERB
fnp-4682	117	34	from	from	ADP
fnp-4682	117	35	acute	acute	ADJ
fnp-4682	117	36	infections	infection	NOUN
fnp-4682	117	37	.	.	PUNCT
fnp-4682	118	1	as	as	SCONJ
fnp-4682	118	2	expected	expect	VERB
fnp-4682	118	3	,	,	PUNCT
fnp-4682	118	4	the	the	DET
fnp-4682	118	5	axonal	axonal	ADJ
fnp-4682	118	6	neuropathy	neuropathy	ADJ
fnp-4682	118	7	phenotype	phenotype	NOUN
fnp-4682	118	8	in	in	ADP
fnp-4682	118	9	model	model	NOUN
fnp-4682	118	10	mice	mouse	NOUN
fnp-4682	118	11	was	be	AUX
fnp-4682	118	12	rescued	rescue	VERB
fnp-4682	118	13	by	by	ADP
fnp-4682	118	14	simultaneous	simultaneous	ADJ
fnp-4682	118	15	deletion	deletion	NOUN
fnp-4682	118	16	of	of	ADP
fnp-4682	118	17	sarm1	sarm1	PROPN
fnp-4682	118	18	(	(	PUNCT
fnp-4682	118	19	fig	fig	NOUN
fnp-4682	118	20	.	.	PUNCT
fnp-4682	119	1	3d	3d	NUM
fnp-4682	119	2	-	-	PUNCT
fnp-4682	119	3	f	f	NOUN
fnp-4682	119	4	)	)	PUNCT
fnp-4682	119	5	,	,	PUNCT
fnp-4682	119	6	demonstrating	demonstrate	VERB
fnp-4682	119	7	that	that	SCONJ
fnp-4682	119	8	sarm1	sarm1	PROPN
fnp-4682	119	9	activation	activation	NOUN
fnp-4682	119	10	was	be	AUX
fnp-4682	119	11	necessary	necessary	ADJ
fnp-4682	119	12	for	for	ADP
fnp-4682	119	13	axon	axon	NOUN
fnp-4682	119	14	degeneration	degeneration	NOUN
fnp-4682	119	15	;	;	PUNCT
fnp-4682	119	16	a	a	DET
fnp-4682	119	17	similar	similar	ADJ
fnp-4682	119	18	,	,	PUNCT
fnp-4682	119	19	but	but	CCONJ
fnp-4682	119	20	slightly	slightly	ADV
fnp-4682	119	21	less	less	ADV
fnp-4682	119	22	effective	effective	ADJ
fnp-4682	119	23	rescue	rescue	NOUN
fnp-4682	119	24	was	be	AUX
fnp-4682	119	25	achieved	achieve	VERB
fnp-4682	119	26	by	by	ADP
fnp-4682	119	27	transgenic	transgenic	NOUN
fnp-4682	119	28	expression	expression	NOUN
fnp-4682	119	29	of	of	ADP
fnp-4682	119	30	a	a	DET
fnp-4682	119	31	dominant	dominant	ADJ
fnp-4682	119	32	negative	negative	ADJ
fnp-4682	119	33	variant	variant	NOUN
fnp-4682	119	34	of	of	ADP
fnp-4682	119	35	sarm1	sarm1	PROPN
fnp-4682	119	36	.	.	PUNCT
fnp-4682	120	1	more	more	ADV
fnp-4682	120	2	surprisingly	surprisingly	ADV
fnp-4682	120	3	,	,	PUNCT
fnp-4682	120	4	the	the	DET
fnp-4682	120	5	sarm1	sarm1	PROPN
fnp-4682	120	6	effect	effect	NOUN
fnp-4682	120	7	in	in	ADP
fnp-4682	120	8	this	this	DET
fnp-4682	120	9	mouse	mouse	NOUN
fnp-4682	120	10	model	model	NOUN
fnp-4682	120	11	was	be	AUX
fnp-4682	120	12	not	not	PART
fnp-4682	120	13	entirely	entirely	ADV
fnp-4682	120	14	cell	cell	NOUN
fnp-4682	120	15	-	-	PUNCT
fnp-4682	120	16	autonomous	autonomous	ADJ
fnp-4682	120	17	;	;	PUNCT
fnp-4682	120	18	instead	instead	ADV
fnp-4682	120	19	,	,	PUNCT
fnp-4682	120	20	it	it	PRON
fnp-4682	120	21	was	be	AUX
fnp-4682	120	22	at	at	ADP
fnp-4682	120	23	least	least	ADJ
fnp-4682	120	24	in	in	ADP
fnp-4682	120	25	part	part	NOUN
fnp-4682	120	26	mediated	mediate	VERB
fnp-4682	120	27	by	by	ADP
fnp-4682	120	28	macrophage	macrophage	ADJ
fnp-4682	120	29	activation	activation	NOUN
fnp-4682	120	30	,	,	PUNCT
fnp-4682	120	31	and	and	CCONJ
fnp-4682	120	32	could	could	AUX
fnp-4682	120	33	therefore	therefore	ADV
fnp-4682	120	34	be	be	AUX
fnp-4682	120	35	blocked	block	VERB
fnp-4682	120	36	by	by	ADP
fnp-4682	120	37	macrophage	macrophage	ADJ
fnp-4682	120	38	depletion	depletion	NOUN
fnp-4682	120	39	(	(	PUNCT
fnp-4682	120	40	via	via	ADP
fnp-4682	120	41	monoclonal	monoclonal	NOUN
fnp-4682	120	42	antibody	antibody	NOUN
fnp-4682	120	43	against	against	ADP
fnp-4682	120	44	colony	colony	NOUN
fnp-4682	120	45	stimulating	stimulate	VERB
fnp-4682	120	46	factor	factor	NOUN
fnp-4682	120	47	1	1	NUM
fnp-4682	120	48	receptor	receptor	NOUN
fnp-4682	120	49	)	)	PUNCT
fnp-4682	120	50	.	.	PUNCT
fnp-4682	121	1	importantly	importantly	ADV
fnp-4682	121	2	,	,	PUNCT
fnp-4682	121	3	macrophage	macrophage	ADJ
fnp-4682	121	4	depletion	depletion	NOUN
fnp-4682	121	5	was	be	AUX
fnp-4682	121	6	effective	effective	ADJ
fnp-4682	121	7	not	not	PART
fnp-4682	121	8	only	only	ADV
fnp-4682	121	9	when	when	SCONJ
fnp-4682	121	10	treatment	treatment	NOUN
fnp-4682	121	11	was	be	AUX
fnp-4682	121	12	started	start	VERB
fnp-4682	121	13	at	at	ADP
fnp-4682	121	14	birth	birth	NOUN
fnp-4682	121	15	,	,	PUNCT
fnp-4682	121	16	but	but	CCONJ
fnp-4682	121	17	also	also	ADV
fnp-4682	121	18	when	when	SCONJ
fnp-4682	121	19	it	it	PRON
fnp-4682	121	20	was	be	AUX
fnp-4682	121	21	started	start	VERB
fnp-4682	121	22	at	at	ADP
fnp-4682	121	23	4	4	NUM
fnp-4682	121	24	months	month	NOUN
fnp-4682	121	25	of	of	ADP
fnp-4682	121	26	age	age	NOUN
fnp-4682	121	27	(	(	PUNCT
fnp-4682	121	28	by	by	ADP
fnp-4682	121	29	which	which	DET
fnp-4682	121	30	point	point	NOUN
fnp-4682	121	31	mice	mouse	NOUN
fnp-4682	121	32	already	already	ADV
fnp-4682	121	33	developed	develop	VERB
fnp-4682	121	34	significant	significant	ADJ
fnp-4682	121	35	neuropathy	neuropathy	ADJ
fnp-4682	121	36	)	)	PUNCT
fnp-4682	121	37	;	;	PUNCT
fnp-4682	121	38	this	this	PRON
fnp-4682	121	39	suggests	suggest	VERB
fnp-4682	121	40	that	that	SCONJ
fnp-4682	121	41	blocking	block	VERB
fnp-4682	121	42	ongoing	ongoing	ADJ
fnp-4682	121	43	axonal	axonal	ADJ
fnp-4682	121	44	degeneration	degeneration	NOUN
fnp-4682	121	45	can	can	AUX
fnp-4682	121	46	tip	tip	VERB
fnp-4682	121	47	the	the	DET
fnp-4682	121	48	balance	balance	NOUN
fnp-4682	121	49	toward	toward	ADP
fnp-4682	121	50	axonal	axonal	ADJ
fnp-4682	121	51	regeneration	regeneration	NOUN
fnp-4682	121	52	and	and	CCONJ
fnp-4682	121	53	functional	functional	ADJ
fnp-4682	121	54	recovery	recovery	NOUN
fnp-4682	121	55	.	.	PUNCT
fnp-4682	122	1	figure	figure	NOUN
fnp-4682	122	2	3	3	NUM
fnp-4682	122	3	.	.	PUNCT
fnp-4682	122	4	nmnat2	nmnat2	NOUN
fnp-4682	122	5	variants	variant	NOUN
fnp-4682	122	6	cause	cause	VERB
fnp-4682	122	7	progressive	progressive	ADJ
fnp-4682	122	8	axon	axon	NOUN
fnp-4682	122	9	loss	loss	NOUN
fnp-4682	122	10	in	in	ADP
fnp-4682	122	11	mice	mouse	NOUN
fnp-4682	122	12	in	in	ADP
fnp-4682	122	13	a	a	DET
fnp-4682	122	14	sarm1	sarm1	NOUN
fnp-4682	122	15	-	-	PUNCT
fnp-4682	122	16	dependent	dependent	ADJ
fnp-4682	122	17	manner	manner	NOUN
fnp-4682	122	18	.	.	PUNCT
fnp-4682	123	1	(	(	PUNCT
fnp-4682	123	2	a	a	X
fnp-4682	123	3	–	–	PUNCT
fnp-4682	123	4	c	c	NOUN
fnp-4682	123	5	)	)	PUNCT
fnp-4682	123	6	representative	representative	ADJ
fnp-4682	123	7	images	image	NOUN
fnp-4682	123	8	of	of	ADP
fnp-4682	123	9	sciatic	sciatic	ADJ
fnp-4682	123	10	(	(	PUNCT
fnp-4682	123	11	a	a	X
fnp-4682	123	12	)	)	PUNCT
fnp-4682	123	13	,	,	PUNCT
fnp-4682	123	14	femoral	femoral	ADJ
fnp-4682	123	15	(	(	PUNCT
fnp-4682	123	16	b	b	NOUN
fnp-4682	123	17	)	)	PUNCT
fnp-4682	123	18	,	,	PUNCT
fnp-4682	123	19	and	and	CCONJ
fnp-4682	123	20	sural	sural	ADJ
fnp-4682	123	21	(	(	PUNCT
fnp-4682	123	22	c	c	NOUN
fnp-4682	123	23	)	)	PUNCT
fnp-4682	123	24	nerves	nerve	NOUN
fnp-4682	123	25	in	in	ADP
fnp-4682	123	26	9–12	9–12	NOUN
fnp-4682	123	27	-	-	PUNCT
fnp-4682	123	28	month	month	NOUN
fnp-4682	123	29	-	-	PUNCT
fnp-4682	123	30	old	old	ADJ
fnp-4682	123	31	nmnat2v98m	nmnat2v98m	NOUN
fnp-4682	123	32	/	/	SYM
fnp-4682	123	33	r232q	r232q	PROPN
fnp-4682	123	34	(	(	PUNCT
fnp-4682	123	35	n	n	NOUN
fnp-4682	123	36	=	=	SYM
fnp-4682	123	37	9	9	NUM
fnp-4682	123	38	)	)	PUNCT
fnp-4682	123	39	or	or	CCONJ
fnp-4682	123	40	wt	wt	INTJ
fnp-4682	123	41	(	(	PUNCT
fnp-4682	123	42	n	n	NOUN
fnp-4682	123	43	=	=	SYM
fnp-4682	123	44	5	5	NUM
fnp-4682	123	45	)	)	PUNCT
fnp-4682	123	46	mice	mouse	NOUN
fnp-4682	123	47	.	.	PUNCT
fnp-4682	124	1	percent	percent	NOUN
fnp-4682	124	2	axonal	axonal	ADJ
fnp-4682	124	3	area	area	NOUN
fnp-4682	124	4	/	/	SYM
fnp-4682	124	5	total	total	NOUN
fnp-4682	124	6	nerve	nerve	NOUN
fnp-4682	124	7	area	area	NOUN
fnp-4682	124	8	are	be	AUX
fnp-4682	124	9	indicated	indicate	VERB
fnp-4682	124	10	to	to	ADP
fnp-4682	124	11	the	the	DET
fnp-4682	124	12	right	right	NOUN
fnp-4682	124	13	(	(	PUNCT
fnp-4682	124	14	n	n	NOUN
fnp-4682	124	15	=	=	SYM
fnp-4682	124	16	4–11	4–11	NOUN
fnp-4682	124	17	mice	mouse	NOUN
fnp-4682	124	18	per	per	ADP
fnp-4682	124	19	age	age	NOUN
fnp-4682	124	20	cohort	cohort	NOUN
fnp-4682	124	21	,	,	PUNCT
fnp-4682	124	22	per	per	ADP
fnp-4682	124	23	genotype	genotype	NOUN
fnp-4682	124	24	)	)	PUNCT
fnp-4682	124	25	.	.	PUNCT
fnp-4682	125	1	(	(	PUNCT
fnp-4682	125	2	d	d	X
fnp-4682	125	3	–	–	PUNCT
fnp-4682	125	4	f	f	X
fnp-4682	125	5	)	)	PUNCT
fnp-4682	125	6	representative	representative	ADJ
fnp-4682	125	7	images	image	NOUN
fnp-4682	125	8	of	of	ADP
fnp-4682	125	9	sciatic	sciatic	ADJ
fnp-4682	125	10	(	(	PUNCT
fnp-4682	125	11	d	d	NOUN
fnp-4682	125	12	)	)	PUNCT
fnp-4682	125	13	,	,	PUNCT
fnp-4682	125	14	femoral	femoral	ADJ
fnp-4682	125	15	(	(	PUNCT
fnp-4682	125	16	e	e	NOUN
fnp-4682	125	17	)	)	PUNCT
fnp-4682	125	18	,	,	PUNCT
fnp-4682	125	19	and	and	CCONJ
fnp-4682	125	20	sural	sural	ADJ
fnp-4682	125	21	(	(	PUNCT
fnp-4682	125	22	f	f	X
fnp-4682	125	23	)	)	PUNCT
fnp-4682	125	24	nerves	nerve	NOUN
fnp-4682	125	25	in	in	ADP
fnp-4682	125	26	9–12	9–12	NOUN
fnp-4682	125	27	-	-	PUNCT
fnp-4682	125	28	month	month	NOUN
fnp-4682	125	29	-	-	PUNCT
fnp-4682	125	30	old	old	ADJ
fnp-4682	125	31	nmnat2v98m	nmnat2v98m	NOUN
fnp-4682	125	32	/	/	SYM
fnp-4682	125	33	r232q	r232q	PROPN
fnp-4682	125	34	;	;	PUNCT
fnp-4682	125	35	sarm1	sarm1	PROPN
fnp-4682	125	36	-	-	PUNCT
fnp-4682	125	37	ko	ko	PROPN
fnp-4682	125	38	mice	mouse	NOUN
fnp-4682	125	39	.	.	PUNCT
fnp-4682	126	1	percent	percent	NOUN
fnp-4682	126	2	axonal	axonal	ADJ
fnp-4682	126	3	area	area	NOUN
fnp-4682	126	4	/	/	SYM
fnp-4682	126	5	total	total	NOUN
fnp-4682	126	6	nerve	nerve	NOUN
fnp-4682	126	7	area	area	NOUN
fnp-4682	126	8	is	be	AUX
fnp-4682	126	9	calculated	calculate	VERB
fnp-4682	126	10	below	below	ADP
fnp-4682	126	11	each	each	DET
fnp-4682	126	12	corresponding	correspond	VERB
fnp-4682	126	13	nerve	nerve	NOUN
fnp-4682	126	14	(	(	PUNCT
fnp-4682	126	15	n	n	NOUN
fnp-4682	126	16	=	=	SYM
fnp-4682	126	17	3–11	3–11	NOUN
fnp-4682	126	18	mice	mouse	NOUN
fnp-4682	126	19	per	per	ADP
fnp-4682	126	20	age	age	NOUN
fnp-4682	126	21	cohort	cohort	NOUN
fnp-4682	126	22	,	,	PUNCT
fnp-4682	126	23	per	per	ADP
fnp-4682	126	24	genotype	genotype	NOUN
fnp-4682	126	25	)	)	PUNCT
fnp-4682	126	26	.	.	PUNCT
fnp-4682	127	1	statistical	statistical	ADJ
fnp-4682	127	2	significance	significance	NOUN
fnp-4682	127	3	was	be	AUX
fnp-4682	127	4	determined	determine	VERB
fnp-4682	127	5	by	by	ADP
fnp-4682	127	6	2	2	NUM
fnp-4682	127	7	-	-	PUNCT
fnp-4682	127	8	way	way	NOUN
fnp-4682	127	9	anova	anova	X
fnp-4682	127	10	with	with	ADP
fnp-4682	127	11	multiple	multiple	ADJ
fnp-4682	127	12	comparisons	comparison	NOUN
fnp-4682	127	13	.	.	PUNCT
fnp-4682	128	1	*	*	PUNCT
fnp-4682	128	2	p	p	X
fnp-4682	128	3	<	<	X
fnp-4682	128	4	0.05	0.05	NUM
fnp-4682	128	5	,	,	PUNCT
fnp-4682	128	6	*	*	PUNCT
fnp-4682	128	7	*	*	PUNCT
fnp-4682	128	8	p	p	X
fnp-4682	128	9	<	<	X
fnp-4682	128	10	0.01	0.01	NUM
fnp-4682	128	11	,	,	PUNCT
fnp-4682	128	12	*	*	PUNCT
fnp-4682	128	13	*	*	PUNCT
fnp-4682	128	14	*	*	PUNCT
fnp-4682	128	15	p	p	X
fnp-4682	128	16	<	<	X
fnp-4682	128	17	0.001	0.001	NUM
fnp-4682	128	18	,	,	PUNCT
fnp-4682	128	19	*	*	PUNCT
fnp-4682	128	20	*	*	PUNCT
fnp-4682	128	21	*	*	PUNCT
fnp-4682	128	22	*	*	PUNCT
fnp-4682	128	23	p	p	X
fnp-4682	128	24	<	<	X
fnp-4682	128	25	0.0001	0.0001	NUM
fnp-4682	128	26	.	.	PUNCT
fnp-4682	128	27	scale	scale	NOUN
fnp-4682	128	28	bars	bar	NOUN
fnp-4682	128	29	,	,	PUNCT
fnp-4682	128	30	50	50	NUM
fnp-4682	128	31	μm	μm	NOUN
fnp-4682	128	32	.	.	PUNCT
fnp-4682	129	1	[	[	X
fnp-4682	129	2	this	this	DET
fnp-4682	129	3	figure	figure	NOUN
fnp-4682	129	4	and	and	CCONJ
fnp-4682	129	5	its	its	PRON
fnp-4682	129	6	legend	legend	NOUN
fnp-4682	129	7	were	be	AUX
fnp-4682	129	8	adopted	adopt	VERB
fnp-4682	129	9	from	from	ADP
fnp-4682	129	10	figures	figure	NOUN
fnp-4682	129	11	3	3	NUM
fnp-4682	129	12	(	(	PUNCT
fnp-4682	129	13	a	a	NOUN
fnp-4682	129	14	-	-	PUNCT
fnp-4682	129	15	c	c	NOUN
fnp-4682	129	16	)	)	PUNCT
fnp-4682	129	17	and	and	CCONJ
fnp-4682	129	18	5	5	NUM
fnp-4682	129	19	(	(	PUNCT
fnp-4682	129	20	d	d	NOUN
fnp-4682	129	21	-	-	PUNCT
fnp-4682	129	22	f	f	NOUN
fnp-4682	129	23	)	)	PUNCT
fnp-4682	129	24	in	in	ADP
fnp-4682	129	25	(	(	PUNCT
fnp-4682	129	26	dingwall	dingwall	PROPN
fnp-4682	129	27	et	et	PROPN
fnp-4682	129	28	al	al	PROPN
fnp-4682	129	29	.	.	PROPN
fnp-4682	129	30	,	,	PUNCT
fnp-4682	129	31	2022	2022	NUM
fnp-4682	129	32	)	)	PUNCT
fnp-4682	129	33	;	;	PUNCT
fnp-4682	129	34	this	this	DET
fnp-4682	129	35	use	use	NOUN
fnp-4682	129	36	is	be	AUX
fnp-4682	129	37	permitted	permit	VERB
fnp-4682	129	38	under	under	ADP
fnp-4682	129	39	the	the	DET
fnp-4682	129	40	creative	creative	ADJ
fnp-4682	129	41	commons	common	NOUN
fnp-4682	129	42	attribution	attribution	NOUN
fnp-4682	129	43	4.0	4.0	NUM
fnp-4682	129	44	cc	cc	NOUN
fnp-4682	129	45	-	-	PUNCT
fnp-4682	129	46	by	by	ADP
fnp-4682	129	47	international	international	ADJ
fnp-4682	129	48	license	license	NOUN
fnp-4682	129	49	.	.	PUNCT
fnp-4682	129	50	]	]	PUNCT
fnp-4682	130	1	as	as	ADP
fnp-4682	130	2	always	always	ADV
fnp-4682	130	3	,	,	PUNCT
fnp-4682	130	4	many	many	ADJ
fnp-4682	130	5	questions	question	NOUN
fnp-4682	130	6	remain	remain	VERB
fnp-4682	130	7	to	to	PART
fnp-4682	130	8	be	be	AUX
fnp-4682	130	9	answered	answer	VERB
fnp-4682	130	10	.	.	PUNCT
fnp-4682	131	1	in	in	ADP
fnp-4682	131	2	particular	particular	ADJ
fnp-4682	131	3	,	,	PUNCT
fnp-4682	131	4	it	it	PRON
fnp-4682	131	5	is	be	AUX
fnp-4682	131	6	not	not	PART
fnp-4682	131	7	clear	clear	ADJ
fnp-4682	131	8	why	why	SCONJ
fnp-4682	131	9	acute	acute	ADJ
fnp-4682	131	10	attacks	attack	NOUN
fnp-4682	131	11	in	in	ADP
fnp-4682	131	12	human	human	ADJ
fnp-4682	131	13	patients	patient	NOUN
fnp-4682	131	14	involve	involve	VERB
fnp-4682	131	15	both	both	DET
fnp-4682	131	16	sensory	sensory	ADJ
fnp-4682	131	17	and	and	CCONJ
fnp-4682	131	18	motor	motor	NOUN
fnp-4682	131	19	nerves	nerve	NOUN
fnp-4682	131	20	,	,	PUNCT
fnp-4682	131	21	while	while	SCONJ
fnp-4682	131	22	chronic	chronic	ADJ
fnp-4682	131	23	neuropathy	neuropathy	ADJ
fnp-4682	131	24	predominantly	predominantly	ADV
fnp-4682	131	25	affects	affect	VERB
fnp-4682	131	26	motor	motor	NOUN
fnp-4682	131	27	nerves	nerve	NOUN
fnp-4682	131	28	in	in	ADP
fnp-4682	131	29	humans	human	NOUN
fnp-4682	131	30	as	as	ADV
fnp-4682	131	31	well	well	ADV
fnp-4682	131	32	as	as	ADP
fnp-4682	131	33	mice	mouse	NOUN
fnp-4682	131	34	.	.	PUNCT
fnp-4682	132	1	[	[	X
fnp-4682	132	2	preferential	preferential	ADJ
fnp-4682	132	3	involvement	involvement	NOUN
fnp-4682	132	4	of	of	ADP
fnp-4682	132	5	motor	motor	NOUN
fnp-4682	132	6	axons	axon	NOUN
fnp-4682	132	7	in	in	ADP
fnp-4682	132	8	the	the	DET
fnp-4682	132	9	mouse	mouse	NOUN
fnp-4682	132	10	model	model	NOUN
fnp-4682	132	11	can	can	AUX
fnp-4682	132	12	be	be	AUX
fnp-4682	132	13	attributed	attribute	VERB
fnp-4682	132	14	to	to	ADP
fnp-4682	132	15	differences	difference	NOUN
fnp-4682	132	16	in	in	ADP
fnp-4682	132	17	macrophage	macrophage	ADJ
fnp-4682	132	18	activation	activation	NOUN
fnp-4682	132	19	between	between	ADP
fnp-4682	132	20	sensory	sensory	ADJ
fnp-4682	132	21	and	and	CCONJ
fnp-4682	132	22	motor	motor	NOUN
fnp-4682	132	23	nerves	nerve	NOUN
fnp-4682	132	24	;	;	PUNCT
fnp-4682	132	25	however	however	ADV
fnp-4682	132	26	,	,	PUNCT
fnp-4682	132	27	given	give	VERB
fnp-4682	132	28	that	that	PRON
fnp-4682	132	29	increased	increase	VERB
fnp-4682	132	30	sarm1	sarm1	PROPN
fnp-4682	132	31	activity	activity	NOUN
fnp-4682	132	32	is	be	AUX
fnp-4682	132	33	observed	observe	VERB
fnp-4682	132	34	in	in	ADP
fnp-4682	132	35	both	both	DET
fnp-4682	132	36	nerve	nerve	NOUN
fnp-4682	132	37	types	type	NOUN
fnp-4682	132	38	,	,	PUNCT
fnp-4682	132	39	it	it	PRON
fnp-4682	132	40	is	be	AUX
fnp-4682	132	41	not	not	PART
fnp-4682	132	42	clear	clear	ADJ
fnp-4682	132	43	what	what	PRON
fnp-4682	132	44	leads	lead	VERB
fnp-4682	132	45	to	to	ADP
fnp-4682	132	46	these	these	DET
fnp-4682	132	47	nerve	nerve	NOUN
fnp-4682	132	48	-	-	PUNCT
fnp-4682	132	49	specific	specific	ADJ
fnp-4682	132	50	differences	difference	NOUN
fnp-4682	132	51	in	in	ADP
fnp-4682	132	52	macrophage	macrophage	ADJ
fnp-4682	132	53	activation	activation	NOUN
fnp-4682	132	54	.	.	PUNCT
fnp-4682	133	1	it	it	PRON
fnp-4682	133	2	is	be	AUX
fnp-4682	133	3	also	also	ADV
fnp-4682	133	4	possible	possible	ADJ
fnp-4682	133	5	that	that	SCONJ
fnp-4682	133	6	motor	motor	NOUN
fnp-4682	133	7	neurons	neuron	NOUN
fnp-4682	133	8	are	be	AUX
fnp-4682	133	9	particularly	particularly	ADV
fnp-4682	133	10	vulnerable	vulnerable	ADJ
fnp-4682	133	11	to	to	ADP
fnp-4682	133	12	sarm1	sarm1	NOUN
fnp-4682	133	13	activation	activation	NOUN
fnp-4682	133	14	;	;	PUNCT
fnp-4682	133	15	in	in	ADP
fnp-4682	133	16	agreement	agreement	NOUN
fnp-4682	133	17	with	with	ADP
fnp-4682	133	18	that	that	DET
fnp-4682	133	19	possibility	possibility	NOUN
fnp-4682	133	20	,	,	PUNCT
fnp-4682	133	21	hypermorphic	hypermorphic	ADJ
fnp-4682	133	22	sarm1	sarm1	PUNCT
fnp-4682	133	23	variants	variant	NOUN
fnp-4682	133	24	were	be	AUX
fnp-4682	133	25	found	find	VERB
fnp-4682	133	26	to	to	PART
fnp-4682	133	27	be	be	AUX
fnp-4682	133	28	enriched	enrich	VERB
fnp-4682	133	29	in	in	ADP
fnp-4682	133	30	patients	patient	NOUN
fnp-4682	133	31	with	with	ADP
fnp-4682	133	32	amyotrophic	amyotrophic	ADJ
fnp-4682	133	33	lateral	lateral	ADJ
fnp-4682	133	34	sclerosis	sclerosis	NOUN
fnp-4682	133	35	(	(	PUNCT
fnp-4682	133	36	als	als	NOUN
fnp-4682	133	37	)	)	PUNCT
fnp-4682	133	38	;	;	PUNCT
fnp-4682	133	39	(	(	PUNCT
fnp-4682	133	40	gilley	gilley	NOUN
fnp-4682	133	41	et	et	NOUN
fnp-4682	133	42	al	al	PROPN
fnp-4682	133	43	.	.	PROPN
fnp-4682	133	44	,	,	PUNCT
fnp-4682	133	45	2021	2021	NUM
fnp-4682	133	46	;	;	PUNCT
fnp-4682	133	47	bloom	bloom	NOUN
fnp-4682	133	48	et	et	PROPN
fnp-4682	133	49	al	al	PROPN
fnp-4682	133	50	.	.	PROPN
fnp-4682	133	51	,	,	PUNCT
fnp-4682	133	52	2022	2022	NUM
fnp-4682	133	53	)	)	PUNCT
fnp-4682	133	54	]	]	PUNCT
fnp-4682	133	55	.	.	PUNCT
fnp-4682	134	1	moreover	moreover	ADV
fnp-4682	134	2	,	,	PUNCT
fnp-4682	134	3	it	it	PRON
fnp-4682	134	4	is	be	AUX
fnp-4682	134	5	not	not	PART
fnp-4682	134	6	understood	understand	VERB
fnp-4682	134	7	why	why	SCONJ
fnp-4682	134	8	nmnat2	nmnat2	NOUN
fnp-4682	134	9	deficiency	deficiency	NOUN
fnp-4682	134	10	primarily	primarily	ADV
fnp-4682	134	11	affects	affect	VERB
fnp-4682	134	12	peripheral	peripheral	ADJ
fnp-4682	134	13	nerves	nerve	NOUN
fnp-4682	134	14	in	in	ADP
fnp-4682	134	15	both	both	DET
fnp-4682	134	16	mice	mouse	NOUN
fnp-4682	134	17	and	and	CCONJ
fnp-4682	134	18	humans	human	NOUN
fnp-4682	134	19	when	when	SCONJ
fnp-4682	134	20	sarm1	sarm1	PROPN
fnp-4682	134	21	acts	act	VERB
fnp-4682	134	22	as	as	ADP
fnp-4682	134	23	the	the	DET
fnp-4682	134	24	central	central	ADJ
fnp-4682	134	25	regulator	regulator	NOUN
fnp-4682	134	26	of	of	ADP
fnp-4682	134	27	wallerian	wallerian	ADJ
fnp-4682	134	28	degeneration	degeneration	NOUN
fnp-4682	134	29	in	in	ADP
fnp-4682	134	30	both	both	CCONJ
fnp-4682	134	31	cns	cns	NOUN
fnp-4682	134	32	and	and	CCONJ
fnp-4682	134	33	pns	pns	PROPN
fnp-4682	134	34	;	;	PUNCT
fnp-4682	134	35	a	a	DET
fnp-4682	134	36	plausible	plausible	ADJ
fnp-4682	134	37	explanation	explanation	NOUN
fnp-4682	134	38	that	that	PRON
fnp-4682	134	39	needs	need	VERB
fnp-4682	134	40	experimental	experimental	ADJ
fnp-4682	134	41	confirmation	confirmation	NOUN
fnp-4682	134	42	is	be	AUX
fnp-4682	134	43	that	that	ADV
fnp-4682	134	44	longer	long	ADJ
fnp-4682	134	45	length	length	NOUN
fnp-4682	134	46	of	of	ADP
fnp-4682	134	47	pns	pns	PROPN
fnp-4682	134	48	axons	axon	NOUN
fnp-4682	134	49	makes	make	VERB
fnp-4682	134	50	them	they	PRON
fnp-4682	134	51	more	more	ADV
fnp-4682	134	52	vulnerable	vulnerable	ADJ
fnp-4682	134	53	to	to	ADP
fnp-4682	134	54	nmnat2	nmnat2	NOUN
fnp-4682	134	55	deficiency	deficiency	NOUN
fnp-4682	134	56	.	.	PUNCT
fnp-4682	135	1	finally	finally	ADV
fnp-4682	135	2	,	,	PUNCT
fnp-4682	135	3	the	the	DET
fnp-4682	135	4	prodegenerative	prodegenerative	ADJ
fnp-4682	135	5	effect	effect	NOUN
fnp-4682	135	6	of	of	ADP
fnp-4682	135	7	macrophage	macrophage	ADJ
fnp-4682	135	8	activation	activation	NOUN
fnp-4682	135	9	in	in	ADP
fnp-4682	135	10	the	the	DET
fnp-4682	135	11	nmnat2v98m	nmnat2v98m	NOUN
fnp-4682	135	12	/	/	SYM
fnp-4682	135	13	r232q	r232q	PROPN
fnp-4682	135	14	mouse	mouse	NOUN
fnp-4682	135	15	model	model	NOUN
fnp-4682	135	16	was	be	AUX
fnp-4682	135	17	entirely	entirely	ADV
fnp-4682	135	18	unexpected	unexpected	ADJ
fnp-4682	135	19	,	,	PUNCT
fnp-4682	135	20	not	not	PART
fnp-4682	135	21	only	only	ADV
fnp-4682	135	22	because	because	SCONJ
fnp-4682	135	23	it	it	PRON
fnp-4682	135	24	was	be	AUX
fnp-4682	135	25	previously	previously	ADV
fnp-4682	135	26	thought	think	VERB
fnp-4682	135	27	that	that	SCONJ
fnp-4682	135	28	sarm1	sarm1	PROPN
fnp-4682	135	29	acts	act	VERB
fnp-4682	135	30	in	in	ADP
fnp-4682	135	31	an	an	DET
fnp-4682	135	32	entirely	entirely	ADV
fnp-4682	135	33	cell	cell	NOUN
fnp-4682	135	34	-	-	PUNCT
fnp-4682	135	35	autonomous	autonomous	ADJ
fnp-4682	135	36	manner	manner	NOUN
fnp-4682	135	37	,	,	PUNCT
fnp-4682	135	38	but	but	CCONJ
fnp-4682	135	39	also	also	ADV
fnp-4682	135	40	because	because	SCONJ
fnp-4682	135	41	of	of	ADP
fnp-4682	135	42	a	a	DET
fnp-4682	135	43	large	large	ADJ
fnp-4682	135	44	body	body	NOUN
fnp-4682	135	45	of	of	ADP
fnp-4682	135	46	prior	prior	ADJ
fnp-4682	135	47	research	research	NOUN
fnp-4682	135	48	that	that	PRON
fnp-4682	135	49	demonstrated	demonstrate	VERB
fnp-4682	135	50	a	a	DET
fnp-4682	135	51	key	key	ADJ
fnp-4682	135	52	role	role	NOUN
fnp-4682	135	53	of	of	ADP
fnp-4682	135	54	macrophages	macrophage	NOUN
fnp-4682	135	55	in	in	ADP
fnp-4682	135	56	axon	axon	NOUN
fnp-4682	135	57	regeneration	regeneration	NOUN
fnp-4682	136	1	[	[	PUNCT
fnp-4682	136	2	as	as	SCONJ
fnp-4682	136	3	discussed	discuss	VERB
fnp-4682	136	4	in	in	ADP
fnp-4682	136	5	advance	advance	NOUN
fnp-4682	136	6	#	#	SYM
fnp-4682	136	7	1	1	NUM
fnp-4682	136	8	of	of	ADP
fnp-4682	136	9	my	my	PRON
fnp-4682	136	10	last	last	ADJ
fnp-4682	136	11	update	update	NOUN
fnp-4682	136	12	(	(	PUNCT
fnp-4682	136	13	margeta	margeta	NOUN
fnp-4682	136	14	,	,	PUNCT
fnp-4682	136	15	2022	2022	NUM
fnp-4682	136	16	)	)	PUNCT
fnp-4682	136	17	]	]	PUNCT
fnp-4682	136	18	.	.	PUNCT
fnp-4682	137	1	these	these	DET
fnp-4682	137	2	discrepancies	discrepancy	NOUN
fnp-4682	137	3	suggest	suggest	VERB
fnp-4682	137	4	that	that	SCONJ
fnp-4682	137	5	macrophage	macrophage	ADJ
fnp-4682	137	6	effects	effect	NOUN
fnp-4682	137	7	on	on	ADP
fnp-4682	137	8	axonal	axonal	ADJ
fnp-4682	137	9	degeneration	degeneration	NOUN
fnp-4682	137	10	are	be	AUX
fnp-4682	137	11	complex	complex	ADJ
fnp-4682	137	12	and	and	CCONJ
fnp-4682	137	13	context	context	NOUN
fnp-4682	137	14	-	-	PUNCT
fnp-4682	137	15	dependent	dependent	ADJ
fnp-4682	137	16	,	,	PUNCT
fnp-4682	137	17	and	and	CCONJ
fnp-4682	137	18	raise	raise	VERB
fnp-4682	137	19	the	the	DET
fnp-4682	137	20	possibility	possibility	NOUN
fnp-4682	137	21	that	that	SCONJ
fnp-4682	137	22	macrophage	macrophage	ADJ
fnp-4682	137	23	depletion	depletion	NOUN
fnp-4682	137	24	therapies	therapy	NOUN
fnp-4682	137	25	could	could	AUX
fnp-4682	137	26	be	be	AUX
fnp-4682	137	27	either	either	CCONJ
fnp-4682	137	28	beneficial	beneficial	ADJ
fnp-4682	137	29	or	or	CCONJ
fnp-4682	137	30	detrimental	detrimental	ADJ
fnp-4682	137	31	,	,	PUNCT
fnp-4682	137	32	depending	depend	VERB
fnp-4682	137	33	on	on	ADP
fnp-4682	137	34	the	the	DET
fnp-4682	137	35	specific	specific	ADJ
fnp-4682	137	36	clinical	clinical	ADJ
fnp-4682	137	37	scenario	scenario	NOUN
fnp-4682	137	38	.	.	PUNCT
fnp-4682	138	1	one	one	NUM
fnp-4682	138	2	intriguing	intriguing	ADJ
fnp-4682	138	3	possibility	possibility	NOUN
fnp-4682	138	4	,	,	PUNCT
fnp-4682	138	5	which	which	PRON
fnp-4682	138	6	needs	need	VERB
fnp-4682	138	7	to	to	PART
fnp-4682	138	8	be	be	AUX
fnp-4682	138	9	addressed	address	VERB
fnp-4682	138	10	by	by	ADP
fnp-4682	138	11	future	future	ADJ
fnp-4682	138	12	studies	study	NOUN
fnp-4682	138	13	,	,	PUNCT
fnp-4682	138	14	is	be	AUX
fnp-4682	138	15	that	that	DET
fnp-4682	138	16	macrophage	macrophage	ADJ
fnp-4682	138	17	activation	activation	NOUN
fnp-4682	138	18	promotes	promote	VERB
fnp-4682	138	19	degeneration	degeneration	NOUN
fnp-4682	138	20	of	of	ADP
fnp-4682	138	21	damaged	damaged	ADJ
fnp-4682	138	22	but	but	CCONJ
fnp-4682	138	23	still	still	ADV
fnp-4682	138	24	viable	viable	ADJ
fnp-4682	138	25	axons	axon	NOUN
fnp-4682	138	26	in	in	ADP
fnp-4682	138	27	chronic	chronic	ADJ
fnp-4682	138	28	axonal	axonal	ADJ
fnp-4682	138	29	neuropathies	neuropathy	NOUN
fnp-4682	138	30	,	,	PUNCT
fnp-4682	138	31	while	while	SCONJ
fnp-4682	138	32	promoting	promote	VERB
fnp-4682	138	33	axonal	axonal	ADJ
fnp-4682	138	34	regeneration	regeneration	NOUN
fnp-4682	138	35	following	follow	VERB
fnp-4682	138	36	severe	severe	ADJ
fnp-4682	138	37	insults	insult	NOUN
fnp-4682	138	38	(	(	PUNCT
fnp-4682	138	39	such	such	ADJ
fnp-4682	138	40	as	as	ADP
fnp-4682	138	41	nerve	nerve	NOUN
fnp-4682	138	42	trauma	trauma	NOUN
fnp-4682	138	43	or	or	CCONJ
fnp-4682	138	44	ischemia	ischemia	NOUN
fnp-4682	138	45	)	)	PUNCT
fnp-4682	138	46	that	that	PRON
fnp-4682	138	47	result	result	VERB
fnp-4682	138	48	in	in	ADP
fnp-4682	138	49	catastrophic	catastrophic	ADJ
fnp-4682	138	50	axonal	axonal	ADJ
fnp-4682	138	51	injury	injury	NOUN
fnp-4682	138	52	.	.	PUNCT
fnp-4682	139	1	advances	advance	NOUN
fnp-4682	139	2	in	in	ADP
fnp-4682	139	3	understanding	understanding	NOUN
fnp-4682	139	4	of	of	ADP
fnp-4682	139	5	etiology	etiology	NOUN
fnp-4682	139	6	and	and	CCONJ
fnp-4682	139	7	pathogenesis	pathogenesis	NOUN
fnp-4682	139	8	of	of	ADP
fnp-4682	139	9	neuromuscular	neuromuscular	ADJ
fnp-4682	139	10	diseases	disease	NOUN
fnp-4682	139	11	5	5	NUM
fnp-4682	139	12	.	.	X
fnp-4682	139	13	axonal	axonal	ADJ
fnp-4682	139	14	injury	injury	NOUN
fnp-4682	139	15	in	in	ADP
fnp-4682	139	16	guillain	guillain	NOUN
fnp-4682	139	17	-	-	PUNCT
fnp-4682	139	18	barré	barré	PROPN
fnp-4682	139	19	syndrome	syndrome	NOUN
fnp-4682	139	20	starts	start	VERB
fnp-4682	139	21	at	at	ADP
fnp-4682	139	22	the	the	DET
fnp-4682	139	23	nodes	node	NOUN
fnp-4682	139	24	of	of	ADP
fnp-4682	139	25	ranvier	ranvier	NOUN
fnp-4682	139	26	gbs	gbs	PROPN
fnp-4682	139	27	is	be	AUX
fnp-4682	139	28	an	an	DET
fnp-4682	139	29	autoimmune	autoimmune	ADJ
fnp-4682	139	30	disorder	disorder	NOUN
fnp-4682	139	31	of	of	ADP
fnp-4682	139	32	the	the	DET
fnp-4682	139	33	peripheral	peripheral	ADJ
fnp-4682	139	34	nerves	nerve	NOUN
fnp-4682	139	35	and	and	CCONJ
fnp-4682	139	36	spinal	spinal	ADJ
fnp-4682	139	37	roots	root	NOUN
fnp-4682	139	38	that	that	PRON
fnp-4682	139	39	is	be	AUX
fnp-4682	139	40	typically	typically	ADV
fnp-4682	139	41	triggered	trigger	VERB
fnp-4682	139	42	by	by	ADP
fnp-4682	139	43	a	a	DET
fnp-4682	139	44	preceding	precede	VERB
fnp-4682	139	45	infection	infection	NOUN
fnp-4682	139	46	or	or	CCONJ
fnp-4682	139	47	vaccination	vaccination	NOUN
fnp-4682	139	48	;	;	PUNCT
fnp-4682	139	49	nerve	nerve	NOUN
fnp-4682	139	50	injury	injury	NOUN
fnp-4682	139	51	is	be	AUX
fnp-4682	139	52	the	the	DET
fnp-4682	139	53	result	result	NOUN
fnp-4682	139	54	of	of	ADP
fnp-4682	139	55	autoantibody	autoantibody	NOUN
fnp-4682	139	56	-	-	PUNCT
fnp-4682	139	57	induced	induce	VERB
fnp-4682	139	58	complement	complement	NOUN
fnp-4682	139	59	fixation	fixation	NOUN
fnp-4682	139	60	and	and	CCONJ
fnp-4682	139	61	macrophage	macrophage	ADJ
fnp-4682	139	62	activation	activation	NOUN
fnp-4682	139	63	.	.	PUNCT
fnp-4682	140	1	while	while	SCONJ
fnp-4682	140	2	gbs	gbs	PROPN
fnp-4682	140	3	is	be	AUX
fnp-4682	140	4	traditionally	traditionally	ADV
fnp-4682	140	5	considered	consider	VERB
fnp-4682	140	6	to	to	PART
fnp-4682	140	7	be	be	AUX
fnp-4682	140	8	a	a	DET
fnp-4682	140	9	demyelinating	demyelinate	VERB
fnp-4682	140	10	disease	disease	NOUN
fnp-4682	140	11	(	(	PUNCT
fnp-4682	140	12	also	also	ADV
fnp-4682	140	13	known	know	VERB
fnp-4682	140	14	as	as	ADP
fnp-4682	140	15	acute	acute	ADJ
fnp-4682	140	16	inflammatory	inflammatory	ADJ
fnp-4682	140	17	demyelinating	demyelinate	VERB
fnp-4682	140	18	polyneuropathy	polyneuropathy	ADJ
fnp-4682	140	19	/	/	SYM
fnp-4682	140	20	aidp	aidp	NOUN
fnp-4682	140	21	)	)	PUNCT
fnp-4682	140	22	,	,	PUNCT
fnp-4682	140	23	it	it	PRON
fnp-4682	140	24	can	can	AUX
fnp-4682	140	25	also	also	ADV
fnp-4682	140	26	manifest	manifest	VERB
fnp-4682	140	27	as	as	ADP
fnp-4682	140	28	a	a	DET
fnp-4682	140	29	primary	primary	ADJ
fnp-4682	140	30	acute	acute	NOUN
fnp-4682	140	31	motor	motor	NOUN
fnp-4682	140	32	or	or	CCONJ
fnp-4682	140	33	sensorimotor	sensorimotor	NOUN
fnp-4682	140	34	axonal	axonal	ADJ
fnp-4682	140	35	neuropathy	neuropathy	ADJ
fnp-4682	140	36	(	(	PUNCT
fnp-4682	140	37	aman	aman	NOUN
fnp-4682	140	38	/	/	SYM
fnp-4682	140	39	amsan	amsan	NOUN
fnp-4682	140	40	)	)	PUNCT
fnp-4682	140	41	.	.	PUNCT
fnp-4682	141	1	bystander	bystander	ADP
fnp-4682	141	2	axonal	axonal	ADJ
fnp-4682	141	3	injury	injury	NOUN
fnp-4682	141	4	can	can	AUX
fnp-4682	141	5	also	also	ADV
fnp-4682	141	6	develop	develop	VERB
fnp-4682	141	7	in	in	ADP
fnp-4682	141	8	the	the	DET
fnp-4682	141	9	aidp	aidp	ADJ
fnp-4682	141	10	variant	variant	NOUN
fnp-4682	141	11	of	of	ADP
fnp-4682	141	12	gbs	gbs	PROPN
fnp-4682	141	13	,	,	PUNCT
fnp-4682	141	14	secondary	secondary	ADJ
fnp-4682	141	15	to	to	ADP
fnp-4682	141	16	schwann	schwann	PROPN
fnp-4682	141	17	cell	cell	PROPN
fnp-4682	141	18	(	(	PUNCT
fnp-4682	141	19	sc	sc	PROPN
fnp-4682	141	20	)	)	PUNCT
fnp-4682	141	21	injury	injury	NOUN
fnp-4682	141	22	.	.	PUNCT
fnp-4682	142	1	regardless	regardless	ADV
fnp-4682	142	2	of	of	ADP
fnp-4682	142	3	the	the	DET
fnp-4682	142	4	disease	disease	NOUN
fnp-4682	142	5	variant	variant	NOUN
fnp-4682	142	6	,	,	PUNCT
fnp-4682	142	7	the	the	DET
fnp-4682	142	8	long	long	ADJ
fnp-4682	142	9	-	-	PUNCT
fnp-4682	142	10	term	term	NOUN
fnp-4682	142	11	severity	severity	NOUN
fnp-4682	142	12	of	of	ADP
fnp-4682	142	13	gbs	gbs	PROPN
fnp-4682	142	14	is	be	AUX
fnp-4682	142	15	ultimately	ultimately	ADV
fnp-4682	142	16	determined	determine	VERB
fnp-4682	142	17	by	by	ADP
fnp-4682	142	18	the	the	DET
fnp-4682	142	19	extent	extent	NOUN
fnp-4682	142	20	of	of	ADP
fnp-4682	142	21	axon	axon	NOUN
fnp-4682	142	22	loss	loss	NOUN
fnp-4682	142	23	,	,	PUNCT
fnp-4682	142	24	which	which	PRON
fnp-4682	142	25	is	be	AUX
fnp-4682	142	26	less	less	ADV
fnp-4682	142	27	reversible	reversible	ADJ
fnp-4682	142	28	than	than	ADP
fnp-4682	142	29	the	the	DET
fnp-4682	142	30	myelin	myelin	NOUN
fnp-4682	142	31	loss	loss	NOUN
fnp-4682	142	32	;	;	PUNCT
fnp-4682	142	33	however	however	ADV
fnp-4682	142	34	,	,	PUNCT
fnp-4682	142	35	the	the	DET
fnp-4682	142	36	mechanisms	mechanism	NOUN
fnp-4682	142	37	that	that	PRON
fnp-4682	142	38	underlie	underlie	VERB
fnp-4682	142	39	the	the	DET
fnp-4682	142	40	primary	primary	ADJ
fnp-4682	142	41	and	and	CCONJ
fnp-4682	142	42	secondary	secondary	ADJ
fnp-4682	142	43	axon	axon	NOUN
fnp-4682	142	44	injury	injury	NOUN
fnp-4682	142	45	in	in	ADP
fnp-4682	142	46	gbs	gbs	PROPN
fnp-4682	142	47	have	have	AUX
fnp-4682	142	48	been	be	AUX
fnp-4682	142	49	difficult	difficult	ADJ
fnp-4682	142	50	to	to	PART
fnp-4682	142	51	dissect	dissect	VERB
fnp-4682	142	52	because	because	SCONJ
fnp-4682	142	53	the	the	DET
fnp-4682	142	54	key	key	ADJ
fnp-4682	142	55	autoantibody	autoantibody	ADJ
fnp-4682	142	56	targets	target	NOUN
fnp-4682	142	57	(	(	PUNCT
fnp-4682	142	58	such	such	ADJ
fnp-4682	142	59	as	as	ADP
fnp-4682	142	60	gm1	gm1	PROPN
fnp-4682	142	61	gangliosides	ganglioside	NOUN
fnp-4682	142	62	)	)	PUNCT
fnp-4682	142	63	are	be	AUX
fnp-4682	142	64	often	often	ADV
fnp-4682	142	65	expressed	express	VERB
fnp-4682	142	66	by	by	ADP
fnp-4682	142	67	both	both	DET
fnp-4682	142	68	neurons	neuron	NOUN
fnp-4682	142	69	and	and	CCONJ
fnp-4682	142	70	scs	scs	PROPN
fnp-4682	142	71	.	.	PROPN
fnp-4682	142	72	to	to	PART
fnp-4682	142	73	circumvent	circumvent	VERB
fnp-4682	142	74	this	this	DET
fnp-4682	142	75	challenge	challenge	NOUN
fnp-4682	142	76	,	,	PUNCT
fnp-4682	142	77	a	a	DET
fnp-4682	142	78	research	research	NOUN
fnp-4682	142	79	group	group	NOUN
fnp-4682	142	80	in	in	ADP
fnp-4682	142	81	scotland	scotland	PROPN
fnp-4682	142	82	created	create	VERB
fnp-4682	142	83	model	model	NOUN
fnp-4682	142	84	mice	mouse	NOUN
fnp-4682	142	85	that	that	PRON
fnp-4682	142	86	selectively	selectively	ADV
fnp-4682	142	87	express	express	VERB
fnp-4682	142	88	gm1	gm1	PROPN
fnp-4682	142	89	ganglioside	ganglioside	NOUN
fnp-4682	142	90	on	on	ADP
fnp-4682	142	91	either	either	CCONJ
fnp-4682	142	92	sc	sc	PROPN
fnp-4682	142	93	or	or	CCONJ
fnp-4682	142	94	neuronal	neuronal	ADJ
fnp-4682	142	95	membranes	membrane	NOUN
fnp-4682	142	96	;	;	PUNCT
fnp-4682	142	97	the	the	DET
fnp-4682	142	98	peripheral	peripheral	ADJ
fnp-4682	142	99	nerves	nerve	NOUN
fnp-4682	142	100	of	of	ADP
fnp-4682	142	101	these	these	DET
fnp-4682	142	102	mice	mouse	NOUN
fnp-4682	142	103	were	be	AUX
fnp-4682	142	104	then	then	ADV
fnp-4682	142	105	exposed	expose	VERB
fnp-4682	142	106	to	to	ADP
fnp-4682	142	107	monoclonal	monoclonal	NOUN
fnp-4682	142	108	anti	anti	ADJ
fnp-4682	142	109	-	-	ADJ
fnp-4682	142	110	gm1	gm1	ADJ
fnp-4682	142	111	antibodies	antibody	NOUN
fnp-4682	142	112	and	and	CCONJ
fnp-4682	142	113	normal	normal	ADJ
fnp-4682	142	114	human	human	ADJ
fnp-4682	142	115	serum	serum	NOUN
fnp-4682	142	116	(	(	PUNCT
fnp-4682	142	117	as	as	ADP
fnp-4682	142	118	a	a	DET
fnp-4682	142	119	source	source	NOUN
fnp-4682	142	120	of	of	ADP
fnp-4682	142	121	complement	complement	NOUN
fnp-4682	142	122	)	)	PUNCT
fnp-4682	142	123	to	to	PART
fnp-4682	142	124	trigger	trigger	VERB
fnp-4682	142	125	acute	acute	NOUN
fnp-4682	142	126	or	or	CCONJ
fnp-4682	142	127	subacute	subacute	VERB
fnp-4682	142	128	nerve	nerve	NOUN
fnp-4682	142	129	injury	injury	NOUN
fnp-4682	142	130	,	,	PUNCT
fnp-4682	142	131	either	either	CCONJ
fnp-4682	142	132	ex	ex	X
fnp-4682	142	133	vivo	vivo	NOUN
fnp-4682	142	134	(	(	PUNCT
fnp-4682	142	135	in	in	ADP
fnp-4682	142	136	the	the	DET
fnp-4682	142	137	triangularis	triangularis	NOUN
fnp-4682	142	138	sterni	sterni	ADJ
fnp-4682	142	139	nerve	nerve	NOUN
fnp-4682	142	140	-	-	PUNCT
fnp-4682	142	141	muscle	muscle	NOUN
fnp-4682	142	142	preparations	preparation	NOUN
fnp-4682	142	143	)	)	PUNCT
fnp-4682	142	144	or	or	CCONJ
fnp-4682	142	145	in	in	ADP
fnp-4682	142	146	vivo	vivo	NOUN
fnp-4682	142	147	(	(	PUNCT
fnp-4682	142	148	mcgonigal	mcgonigal	PROPN
fnp-4682	142	149	et	et	PROPN
fnp-4682	142	150	al	al	PROPN
fnp-4682	142	151	.	.	PROPN
fnp-4682	142	152	,	,	PUNCT
fnp-4682	142	153	2022	2022	NUM
fnp-4682	142	154	)	)	PUNCT
fnp-4682	142	155	.	.	PUNCT
fnp-4682	143	1	in	in	ADP
fnp-4682	143	2	both	both	DET
fnp-4682	143	3	mouse	mouse	NOUN
fnp-4682	143	4	models	model	NOUN
fnp-4682	143	5	,	,	PUNCT
fnp-4682	143	6	early	early	ADJ
fnp-4682	143	7	injury	injury	NOUN
fnp-4682	144	1	[	[	X
fnp-4682	144	2	following	follow	VERB
fnp-4682	144	3	a	a	DET
fnp-4682	144	4	short	short	ADJ
fnp-4682	144	5	(	(	PUNCT
fnp-4682	144	6	4	4	NUM
fnp-4682	144	7	h	h	NOUN
fnp-4682	144	8	)	)	PUNCT
fnp-4682	144	9	treatment	treatment	NOUN
fnp-4682	144	10	with	with	ADP
fnp-4682	144	11	anti	anti	ADJ
fnp-4682	144	12	-	-	ADJ
fnp-4682	144	13	gm1	gm1	ADJ
fnp-4682	144	14	antibodies	antibody	NOUN
fnp-4682	144	15	and	and	CCONJ
fnp-4682	144	16	complement	complement	NOUN
fnp-4682	144	17	]	]	PUNCT
fnp-4682	144	18	occurred	occur	VERB
fnp-4682	144	19	at	at	ADP
fnp-4682	144	20	the	the	DET
fnp-4682	144	21	nodes	node	NOUN
fnp-4682	144	22	of	of	ADP
fnp-4682	144	23	ranvier	ranvier	NOUN
fnp-4682	144	24	(	(	PUNCT
fnp-4682	144	25	nor	nor	CCONJ
fnp-4682	144	26	)	)	PUNCT
fnp-4682	144	27	;	;	PUNCT
fnp-4682	144	28	this	this	PRON
fnp-4682	144	29	is	be	AUX
fnp-4682	144	30	concordant	concordant	ADJ
fnp-4682	144	31	with	with	ADP
fnp-4682	144	32	the	the	DET
fnp-4682	144	33	neuropathologic	neuropathologic	ADJ
fnp-4682	144	34	studies	study	NOUN
fnp-4682	144	35	of	of	ADP
fnp-4682	144	36	patients	patient	NOUN
fnp-4682	144	37	with	with	ADP
fnp-4682	144	38	gbs	gbs	PROPN
fnp-4682	144	39	,	,	PUNCT
fnp-4682	144	40	which	which	PRON
fnp-4682	144	41	demonstrated	demonstrate	VERB
fnp-4682	144	42	nodal	nodal	NOUN
fnp-4682	144	43	autoantibody	autoantibody	NOUN
fnp-4682	144	44	and	and	CCONJ
fnp-4682	144	45	complement	complement	VERB
fnp-4682	144	46	deposition	deposition	NOUN
fnp-4682	144	47	(	(	PUNCT
fnp-4682	144	48	hafer	hafer	NOUN
fnp-4682	144	49	-	-	PUNCT
fnp-4682	144	50	macko	macko	NOUN
fnp-4682	144	51	et	et	PROPN
fnp-4682	144	52	al	al	PROPN
fnp-4682	144	53	.	.	PROPN
fnp-4682	144	54	,	,	PUNCT
fnp-4682	144	55	1996a	1996a	NUM
fnp-4682	144	56	;	;	PUNCT
fnp-4682	144	57	hafer	hafer	NOUN
fnp-4682	144	58	-	-	PUNCT
fnp-4682	144	59	macko	macko	NOUN
fnp-4682	144	60	et	et	PROPN
fnp-4682	144	61	al	al	PROPN
fnp-4682	144	62	.	.	PROPN
fnp-4682	144	63	,	,	PUNCT
fnp-4682	144	64	1996b	1996b	NUM
fnp-4682	144	65	)	)	PUNCT
fnp-4682	144	66	along	along	ADP
fnp-4682	144	67	with	with	ADP
fnp-4682	144	68	alterations	alteration	NOUN
fnp-4682	144	69	of	of	ADP
fnp-4682	144	70	the	the	DET
fnp-4682	144	71	nodal	nodal	NOUN
fnp-4682	144	72	ultrastructure	ultrastructure	NOUN
fnp-4682	144	73	(	(	PUNCT
fnp-4682	144	74	griffin	griffin	PROPN
fnp-4682	144	75	et	et	PROPN
fnp-4682	144	76	al	al	PROPN
fnp-4682	144	77	.	.	PROPN
fnp-4682	144	78	,	,	PUNCT
fnp-4682	144	79	1996	1996	NUM
fnp-4682	144	80	;	;	PUNCT
fnp-4682	144	81	vallat	vallat	NOUN
fnp-4682	144	82	et	et	NOUN
fnp-4682	144	83	al	al	PROPN
fnp-4682	144	84	.	.	PROPN
fnp-4682	144	85	,	,	PUNCT
fnp-4682	144	86	2020	2020	NUM
fnp-4682	144	87	)	)	PUNCT
fnp-4682	144	88	.	.	PUNCT
fnp-4682	145	1	in	in	ADP
fnp-4682	145	2	neuronal	neuronal	ADJ
fnp-4682	145	3	gbs	gbs	PROPN
fnp-4682	145	4	model	model	NOUN
fnp-4682	145	5	mice	mouse	NOUN
fnp-4682	145	6	(	(	PUNCT
fnp-4682	145	7	which	which	PRON
fnp-4682	145	8	express	express	VERB
fnp-4682	145	9	gm1	gm1	PROPN
fnp-4682	145	10	selectively	selectively	ADV
fnp-4682	145	11	in	in	ADP
fnp-4682	145	12	neurons	neuron	NOUN
fnp-4682	145	13	)	)	PUNCT
fnp-4682	145	14	,	,	PUNCT
fnp-4682	145	15	formation	formation	NOUN
fnp-4682	145	16	of	of	ADP
fnp-4682	145	17	the	the	DET
fnp-4682	145	18	membrane	membrane	NOUN
fnp-4682	145	19	attack	attack	NOUN
fnp-4682	145	20	complex	complex	NOUN
fnp-4682	145	21	(	(	PUNCT
fnp-4682	145	22	mac	mac	NOUN
fnp-4682	145	23	)	)	PUNCT
fnp-4682	145	24	pores	pore	NOUN
fnp-4682	145	25	in	in	ADP
fnp-4682	145	26	the	the	DET
fnp-4682	145	27	nodal	nodal	NOUN
fnp-4682	145	28	axolemma	axolemma	NOUN
fnp-4682	145	29	led	lead	VERB
fnp-4682	145	30	to	to	ADP
fnp-4682	145	31	calpain	calpain	NOUN
fnp-4682	145	32	-	-	PUNCT
fnp-4682	145	33	mediated	mediate	VERB
fnp-4682	145	34	cleavage	cleavage	NOUN
fnp-4682	145	35	of	of	ADP
fnp-4682	145	36	adaptor	adaptor	NOUN
fnp-4682	145	37	protein	protein	NOUN
fnp-4682	145	38	ankyrin	ankyrin	ADJ
fnp-4682	145	39	-	-	PUNCT
fnp-4682	145	40	g	g	NOUN
fnp-4682	145	41	,	,	PUNCT
fnp-4682	145	42	dispersion	dispersion	NOUN
fnp-4682	145	43	and	and	CCONJ
fnp-4682	145	44	disappearance	disappearance	NOUN
fnp-4682	145	45	of	of	ADP
fnp-4682	145	46	the	the	DET
fnp-4682	145	47	nodal	nodal	ADJ
fnp-4682	145	48	sodium	sodium	NOUN
fnp-4682	145	49	channel	channel	NOUN
fnp-4682	145	50	clusters	cluster	NOUN
fnp-4682	145	51	,	,	PUNCT
fnp-4682	145	52	and	and	CCONJ
fnp-4682	145	53	conduction	conduction	NOUN
fnp-4682	145	54	failure	failure	NOUN
fnp-4682	145	55	;	;	PUNCT
fnp-4682	145	56	however	however	ADV
fnp-4682	145	57	,	,	PUNCT
fnp-4682	145	58	there	there	PRON
fnp-4682	145	59	were	be	VERB
fnp-4682	145	60	no	no	DET
fnp-4682	145	61	structural	structural	ADJ
fnp-4682	145	62	changes	change	NOUN
fnp-4682	145	63	in	in	ADP
fnp-4682	145	64	the	the	DET
fnp-4682	145	65	paranodal	paranodal	ADJ
fnp-4682	145	66	sc	sc	PROPN
fnp-4682	145	67	loops	loop	NOUN
fnp-4682	145	68	and	and	CCONJ
fnp-4682	145	69	no	no	DET
fnp-4682	145	70	disruption	disruption	NOUN
fnp-4682	145	71	of	of	ADP
fnp-4682	145	72	the	the	DET
fnp-4682	145	73	cell	cell	NOUN
fnp-4682	145	74	adhesion	adhesion	NOUN
fnp-4682	145	75	complexes	complexe	VERB
fnp-4682	145	76	that	that	PRON
fnp-4682	145	77	form	form	VERB
fnp-4682	145	78	“	"	PUNCT
fnp-4682	145	79	transverse	transverse	NOUN
fnp-4682	145	80	bands	band	NOUN
fnp-4682	145	81	”	"	PUNCT
fnp-4682	145	82	at	at	ADP
fnp-4682	145	83	the	the	DET
fnp-4682	145	84	axo	axo	NOUN
fnp-4682	145	85	-	-	PUNCT
fnp-4682	145	86	glial	glial	ADJ
fnp-4682	145	87	interface	interface	NOUN
fnp-4682	145	88	.	.	PUNCT
fnp-4682	146	1	in	in	ADP
fnp-4682	146	2	glial	glial	ADJ
fnp-4682	146	3	gbs	gbs	PROPN
fnp-4682	146	4	model	model	NOUN
fnp-4682	146	5	mice	mouse	NOUN
fnp-4682	146	6	(	(	PUNCT
fnp-4682	146	7	which	which	PRON
fnp-4682	146	8	express	express	VERB
fnp-4682	146	9	gm1	gm1	PROPN
fnp-4682	146	10	selectively	selectively	ADV
fnp-4682	146	11	in	in	ADP
fnp-4682	146	12	scs	scs	PROPN
fnp-4682	146	13	)	)	PUNCT
fnp-4682	146	14	,	,	PUNCT
fnp-4682	146	15	injury	injury	NOUN
fnp-4682	146	16	started	start	VERB
fnp-4682	146	17	with	with	ADP
fnp-4682	146	18	the	the	DET
fnp-4682	146	19	mac	mac	NOUN
fnp-4682	146	20	-	-	PUNCT
fnp-4682	146	21	induced	induce	VERB
fnp-4682	146	22	distortion	distortion	NOUN
fnp-4682	146	23	of	of	ADP
fnp-4682	146	24	the	the	DET
fnp-4682	146	25	paranodal	paranodal	ADJ
fnp-4682	146	26	sc	sc	PROPN
fnp-4682	146	27	loops	loop	NOUN
fnp-4682	146	28	and	and	CCONJ
fnp-4682	146	29	calpain	calpain	NOUN
fnp-4682	146	30	-	-	PUNCT
fnp-4682	146	31	mediated	mediate	VERB
fnp-4682	146	32	cleavage	cleavage	NOUN
fnp-4682	146	33	of	of	ADP
fnp-4682	146	34	the	the	DET
fnp-4682	146	35	sc	sc	PROPN
fnp-4682	146	36	scaffolding	scaffolding	NOUN
fnp-4682	146	37	protein	protein	NOUN
fnp-4682	146	38	ankyrin	ankyrin	ADJ
fnp-4682	146	39	-	-	PUNCT
fnp-4682	146	40	b	b	NOUN
fnp-4682	146	41	,	,	PUNCT
fnp-4682	146	42	leading	lead	VERB
fnp-4682	146	43	to	to	ADP
fnp-4682	146	44	disruption	disruption	NOUN
fnp-4682	146	45	of	of	ADP
fnp-4682	146	46	transverse	transverse	NOUN
fnp-4682	146	47	bands	band	NOUN
fnp-4682	146	48	,	,	PUNCT
fnp-4682	146	49	dispersion	dispersion	NOUN
fnp-4682	146	50	of	of	ADP
fnp-4682	146	51	the	the	DET
fnp-4682	146	52	sodium	sodium	NOUN
fnp-4682	146	53	channel	channel	NOUN
fnp-4682	146	54	clusters	cluster	NOUN
fnp-4682	146	55	,	,	PUNCT
fnp-4682	146	56	and	and	CCONJ
fnp-4682	146	57	conduction	conduction	NOUN
fnp-4682	146	58	failure	failure	NOUN
fnp-4682	146	59	(	(	PUNCT
fnp-4682	146	60	fig	fig	NOUN
fnp-4682	146	61	.	.	PUNCT
fnp-4682	147	1	4	4	NUM
fnp-4682	147	2	)	)	PUNCT
fnp-4682	147	3	.	.	PUNCT
fnp-4682	148	1	thus	thus	ADV
fnp-4682	148	2	,	,	PUNCT
fnp-4682	148	3	the	the	DET
fnp-4682	148	4	ultimate	ultimate	ADJ
fnp-4682	148	5	functional	functional	ADJ
fnp-4682	148	6	consequence	consequence	NOUN
fnp-4682	148	7	–	–	PUNCT
fnp-4682	148	8	acute	acute	ADJ
fnp-4682	148	9	conduction	conduction	NOUN
fnp-4682	148	10	failure	failure	NOUN
fnp-4682	148	11	–	–	PUNCT
fnp-4682	148	12	was	be	AUX
fnp-4682	148	13	the	the	DET
fnp-4682	148	14	same	same	ADJ
fnp-4682	148	15	in	in	ADP
fnp-4682	148	16	both	both	DET
fnp-4682	148	17	mouse	mouse	NOUN
fnp-4682	148	18	models	model	NOUN
fnp-4682	148	19	,	,	PUNCT
fnp-4682	148	20	although	although	SCONJ
fnp-4682	148	21	the	the	DET
fnp-4682	148	22	underlying	underlie	VERB
fnp-4682	148	23	disease	disease	NOUN
fnp-4682	148	24	mechanisms	mechanism	NOUN
fnp-4682	148	25	and	and	CCONJ
fnp-4682	148	26	associated	associate	VERB
fnp-4682	148	27	structural	structural	ADJ
fnp-4682	148	28	changes	change	NOUN
fnp-4682	148	29	were	be	AUX
fnp-4682	148	30	different	different	ADJ
fnp-4682	148	31	.	.	PUNCT
fnp-4682	149	1	acute	acute	ADJ
fnp-4682	149	2	conduction	conduction	NOUN
fnp-4682	149	3	failure	failure	NOUN
fnp-4682	149	4	–	–	PUNCT
fnp-4682	149	5	which	which	PRON
fnp-4682	149	6	is	be	AUX
fnp-4682	149	7	seen	see	VERB
fnp-4682	149	8	in	in	ADP
fnp-4682	149	9	many	many	ADJ
fnp-4682	149	10	human	human	ADJ
fnp-4682	149	11	gbs	gbs	PROPN
fnp-4682	149	12	patients	patient	NOUN
fnp-4682	149	13	in	in	ADP
fnp-4682	149	14	addition	addition	NOUN
fnp-4682	149	15	to	to	ADP
fnp-4682	149	16	these	these	DET
fnp-4682	149	17	experimental	experimental	ADJ
fnp-4682	149	18	disease	disease	NOUN
fnp-4682	149	19	models	model	NOUN
fnp-4682	149	20	–	–	PUNCT
fnp-4682	149	21	is	be	AUX
fnp-4682	149	22	often	often	ADV
fnp-4682	149	23	temporary	temporary	ADJ
fnp-4682	149	24	and	and	CCONJ
fnp-4682	149	25	reversible	reversible	ADJ
fnp-4682	149	26	;	;	PUNCT
fnp-4682	149	27	however	however	ADV
fnp-4682	149	28	,	,	PUNCT
fnp-4682	149	29	it	it	PRON
fnp-4682	149	30	can	can	AUX
fnp-4682	149	31	also	also	ADV
fnp-4682	149	32	lead	lead	VERB
fnp-4682	149	33	to	to	ADP
fnp-4682	149	34	subsequent	subsequent	ADJ
fnp-4682	149	35	axonal	axonal	ADJ
fnp-4682	149	36	transection	transection	NOUN
fnp-4682	149	37	/	/	SYM
fnp-4682	149	38	wallerian	wallerian	NOUN
fnp-4682	149	39	degeneration	degeneration	NOUN
fnp-4682	149	40	.	.	PUNCT
fnp-4682	150	1	indeed	indeed	ADV
fnp-4682	150	2	,	,	PUNCT
fnp-4682	150	3	extended	extend	VERB
fnp-4682	150	4	(	(	PUNCT
fnp-4682	150	5	20	20	NUM
fnp-4682	150	6	h	h	NOUN
fnp-4682	150	7	)	)	PUNCT
fnp-4682	150	8	treatment	treatment	NOUN
fnp-4682	150	9	with	with	ADP
fnp-4682	150	10	anti	anti	ADJ
fnp-4682	150	11	-	-	ADJ
fnp-4682	150	12	gm1	gm1	ADJ
fnp-4682	150	13	antibodies	antibody	NOUN
fnp-4682	150	14	and	and	CCONJ
fnp-4682	150	15	complement	complement	VERB
fnp-4682	150	16	in	in	ADP
fnp-4682	150	17	vivo	vivo	NOUN
fnp-4682	150	18	led	lead	VERB
fnp-4682	150	19	to	to	ADP
fnp-4682	150	20	a	a	DET
fnp-4682	150	21	loss	loss	NOUN
fnp-4682	150	22	of	of	ADP
fnp-4682	150	23	the	the	DET
fnp-4682	150	24	distal	distal	ADJ
fnp-4682	150	25	motor	motor	NOUN
fnp-4682	150	26	axon	axon	NOUN
fnp-4682	150	27	integrity	integrity	NOUN
fnp-4682	150	28	in	in	ADP
fnp-4682	150	29	glial	glial	ADJ
fnp-4682	150	30	mice	mouse	NOUN
fnp-4682	150	31	,	,	PUNCT
fnp-4682	150	32	indicative	indicative	ADJ
fnp-4682	150	33	of	of	ADP
fnp-4682	150	34	secondary	secondary	ADJ
fnp-4682	150	35	/	/	SYM
fnp-4682	150	36	bystander	bystander	NOUN
fnp-4682	150	37	axonal	axonal	ADJ
fnp-4682	150	38	degeneration	degeneration	NOUN
fnp-4682	150	39	due	due	ADP
fnp-4682	150	40	to	to	ADP
fnp-4682	150	41	nodal	nodal	NOUN
fnp-4682	150	42	sc	sc	PROPN
fnp-4682	150	43	injury	injury	NOUN
fnp-4682	150	44	.	.	PUNCT
fnp-4682	151	1	(	(	PUNCT
fnp-4682	151	2	the	the	DET
fnp-4682	151	3	authors	author	NOUN
fnp-4682	151	4	have	have	VERB
fnp-4682	151	5	yet	yet	ADV
fnp-4682	151	6	to	to	PART
fnp-4682	151	7	perform	perform	VERB
fnp-4682	151	8	similar	similar	ADJ
fnp-4682	151	9	extended	extended	ADJ
fnp-4682	151	10	treatment	treatment	NOUN
fnp-4682	151	11	studies	study	NOUN
fnp-4682	151	12	in	in	ADP
fnp-4682	151	13	their	their	PRON
fnp-4682	151	14	neuronal	neuronal	ADJ
fnp-4682	151	15	mice	mouse	NOUN
fnp-4682	151	16	.	.	PUNCT
fnp-4682	151	17	)	)	PUNCT
fnp-4682	152	1	taken	take	VERB
fnp-4682	152	2	together	together	ADV
fnp-4682	152	3	,	,	PUNCT
fnp-4682	152	4	these	these	DET
fnp-4682	152	5	results	result	NOUN
fnp-4682	152	6	point	point	VERB
fnp-4682	152	7	to	to	ADP
fnp-4682	152	8	nor	nor	CCONJ
fnp-4682	152	9	as	as	ADP
fnp-4682	152	10	the	the	DET
fnp-4682	152	11	site	site	NOUN
fnp-4682	152	12	of	of	ADP
fnp-4682	152	13	initial	initial	ADJ
fnp-4682	152	14	injury	injury	NOUN
fnp-4682	152	15	in	in	ADP
fnp-4682	152	16	both	both	CCONJ
fnp-4682	152	17	neuronal	neuronal	ADJ
fnp-4682	152	18	/	/	SYM
fnp-4682	152	19	axonal	axonal	ADJ
fnp-4682	152	20	and	and	CCONJ
fnp-4682	152	21	glial	glial	ADJ
fnp-4682	152	22	/	/	SYM
fnp-4682	152	23	demyelinating	demyelinate	VERB
fnp-4682	152	24	forms	form	NOUN
fnp-4682	152	25	of	of	ADP
fnp-4682	152	26	gbs	gbs	PROPN
fnp-4682	152	27	.	.	PUNCT
fnp-4682	153	1	[	[	X
fnp-4682	153	2	interestingly	interestingly	ADV
fnp-4682	153	3	,	,	PUNCT
fnp-4682	153	4	nor	nor	CCONJ
fnp-4682	153	5	is	be	AUX
fnp-4682	153	6	also	also	ADV
fnp-4682	153	7	the	the	DET
fnp-4682	153	8	main	main	ADJ
fnp-4682	153	9	site	site	NOUN
fnp-4682	153	10	of	of	ADP
fnp-4682	153	11	injury	injury	NOUN
fnp-4682	153	12	in	in	ADP
fnp-4682	153	13	autoimmune	autoimmune	ADJ
fnp-4682	153	14	nodopathies	nodopathie	NOUN
fnp-4682	153	15	,	,	PUNCT
fnp-4682	153	16	which	which	PRON
fnp-4682	153	17	are	be	AUX
fnp-4682	153	18	caused	cause	VERB
fnp-4682	153	19	by	by	ADP
fnp-4682	153	20	antibodies	antibody	NOUN
fnp-4682	153	21	that	that	SCONJ
fnp-4682	153	22	directly	directly	ADV
fnp-4682	153	23	target	target	VERB
fnp-4682	153	24	glial	glial	ADJ
fnp-4682	153	25	or	or	CCONJ
fnp-4682	153	26	neuronal	neuronal	ADJ
fnp-4682	153	27	cell	cell	NOUN
fnp-4682	153	28	-	-	PUNCT
fnp-4682	153	29	adhesion	adhesion	NOUN
fnp-4682	153	30	molecules	molecule	NOUN
fnp-4682	153	31	expressed	express	VERB
fnp-4682	153	32	in	in	ADP
fnp-4682	153	33	the	the	DET
fnp-4682	153	34	nodal	nodal	NOUN
fnp-4682	153	35	membranes	membrane	NOUN
fnp-4682	153	36	;	;	PUNCT
fnp-4682	153	37	clinically	clinically	ADV
fnp-4682	153	38	,	,	PUNCT
fnp-4682	153	39	autoimmune	autoimmune	ADJ
fnp-4682	153	40	nodopathies	nodopathie	NOUN
fnp-4682	153	41	show	show	VERB
fnp-4682	153	42	significant	significant	ADJ
fnp-4682	153	43	overlap	overlap	NOUN
fnp-4682	153	44	with	with	ADP
fnp-4682	153	45	gbs	gbs	PROPN
fnp-4682	153	46	,	,	PUNCT
fnp-4682	153	47	but	but	CCONJ
fnp-4682	153	48	are	be	AUX
fnp-4682	153	49	typically	typically	ADV
fnp-4682	153	50	more	more	ADV
fnp-4682	153	51	severe	severe	ADJ
fnp-4682	153	52	and	and	CCONJ
fnp-4682	153	53	resistant	resistant	ADJ
fnp-4682	153	54	to	to	ADP
fnp-4682	153	55	ivig	ivig	NOUN
fnp-4682	153	56	immunomodulatory	immunomodulatory	ADJ
fnp-4682	153	57	therapy	therapy	NOUN
fnp-4682	153	58	(	(	PUNCT
fnp-4682	153	59	martin	martin	PROPN
fnp-4682	153	60	-	-	PUNCT
fnp-4682	153	61	aguilar	aguilar	PROPN
fnp-4682	153	62	et	et	PROPN
fnp-4682	153	63	al	al	PROPN
fnp-4682	153	64	.	.	PROPN
fnp-4682	153	65	,	,	PUNCT
fnp-4682	153	66	2022	2022	NUM
fnp-4682	153	67	)	)	PUNCT
fnp-4682	153	68	.	.	PUNCT
fnp-4682	154	1	]	]	PUNCT
fnp-4682	154	2	figure	figure	NOUN
fnp-4682	154	3	4	4	NUM
fnp-4682	154	4	.	.	PUNCT
fnp-4682	155	1	ultrastructural	ultrastructural	ADJ
fnp-4682	155	2	evaluation	evaluation	NOUN
fnp-4682	155	3	of	of	ADP
fnp-4682	155	4	diaphragms	diaphragm	NOUN
fnp-4682	155	5	from	from	ADP
fnp-4682	155	6	in	in	ADP
fnp-4682	155	7	vivo	vivo	ADJ
fnp-4682	155	8	gbs	gbs	PROPN
fnp-4682	155	9	models	model	NOUN
fnp-4682	155	10	.	.	PUNCT
fnp-4682	156	1	neuronal	neuronal	ADJ
fnp-4682	156	2	and	and	CCONJ
fnp-4682	156	3	glial	glial	ADJ
fnp-4682	156	4	mice	mouse	NOUN
fnp-4682	156	5	were	be	AUX
fnp-4682	156	6	dosed	dose	VERB
fnp-4682	156	7	i.p	i.p	PROPN
fnp-4682	156	8	.	.	PROPN
fnp-4682	157	1	with	with	ADP
fnp-4682	157	2	50	50	NUM
fnp-4682	157	3	mg	mg	NUM
fnp-4682	157	4	/	/	SYM
fnp-4682	157	5	kg	kg	NOUN
fnp-4682	157	6	anti	anti	ADJ
fnp-4682	157	7	-	-	PROPN
fnp-4682	157	8	gm1	gm1	PROPN
fnp-4682	157	9	ab	ab	PROPN
fnp-4682	157	10	followed	follow	VERB
fnp-4682	157	11	16	16	NUM
fnp-4682	157	12	hours	hour	NOUN
fnp-4682	157	13	later	later	ADV
fnp-4682	157	14	with	with	ADP
fnp-4682	157	15	30	30	NUM
fnp-4682	157	16	μl	μl	NOUN
fnp-4682	157	17	/	/	SYM
fnp-4682	157	18	g	g	NOUN
fnp-4682	157	19	normal	normal	ADJ
fnp-4682	157	20	human	human	ADJ
fnp-4682	157	21	serum	serum	NOUN
fnp-4682	157	22	(	(	PUNCT
fnp-4682	157	23	nhs	nhs	PROPN
fnp-4682	157	24	)	)	PUNCT
fnp-4682	157	25	(	(	PUNCT
fnp-4682	157	26	injury	injury	NOUN
fnp-4682	157	27	)	)	PUNCT
fnp-4682	157	28	or	or	CCONJ
fnp-4682	157	29	nhs	nhs	NOUN
fnp-4682	157	30	only	only	ADV
fnp-4682	157	31	(	(	PUNCT
fnp-4682	157	32	control	control	NOUN
fnp-4682	157	33	)	)	PUNCT
fnp-4682	157	34	.	.	PUNCT
fnp-4682	158	1	(	(	PUNCT
fnp-4682	158	2	a	a	X
fnp-4682	158	3	)	)	PUNCT
fnp-4682	158	4	a	a	DET
fnp-4682	158	5	normal	normal	ADJ
fnp-4682	158	6	paranode	paranode	NOUN
fnp-4682	158	7	from	from	ADP
fnp-4682	158	8	glial	glial	ADJ
fnp-4682	158	9	control	control	NOUN
fnp-4682	158	10	tissue	tissue	NOUN
fnp-4682	158	11	.	.	PUNCT
fnp-4682	159	1	this	this	DET
fnp-4682	159	2	image	image	NOUN
fnp-4682	159	3	is	be	AUX
fnp-4682	159	4	also	also	ADV
fnp-4682	159	5	representative	representative	ADJ
fnp-4682	159	6	of	of	ADP
fnp-4682	159	7	the	the	DET
fnp-4682	159	8	neuronal	neuronal	ADJ
fnp-4682	159	9	control	control	NOUN
fnp-4682	159	10	nor	nor	CCONJ
fnp-4682	159	11	(	(	PUNCT
fnp-4682	159	12	not	not	PART
fnp-4682	159	13	shown	show	VERB
fnp-4682	159	14	)	)	PUNCT
fnp-4682	159	15	.	.	PUNCT
fnp-4682	160	1	(	(	PUNCT
fnp-4682	160	2	b	b	X
fnp-4682	160	3	)	)	PUNCT
fnp-4682	160	4	higher	high	ADJ
fnp-4682	160	5	magnification	magnification	NOUN
fnp-4682	160	6	of	of	ADP
fnp-4682	160	7	boxed	boxed	ADJ
fnp-4682	160	8	region	region	NOUN
fnp-4682	160	9	from	from	ADP
fnp-4682	160	10	a	a	DET
fnp-4682	160	11	shows	show	NOUN
fnp-4682	160	12	tight	tight	ADJ
fnp-4682	160	13	junctions	junction	NOUN
fnp-4682	160	14	(	(	PUNCT
fnp-4682	160	15	large	large	ADJ
fnp-4682	160	16	arrowhead	arrowhead	NOUN
fnp-4682	160	17	)	)	PUNCT
fnp-4682	160	18	between	between	ADP
fnp-4682	160	19	the	the	DET
fnp-4682	160	20	paranodal	paranodal	ADJ
fnp-4682	160	21	loops	loop	NOUN
fnp-4682	160	22	,	,	PUNCT
fnp-4682	160	23	and	and	CCONJ
fnp-4682	160	24	transverse	transverse	NOUN
fnp-4682	160	25	bands	band	NOUN
fnp-4682	160	26	(	(	PUNCT
fnp-4682	160	27	tbs	tbs	ADJ
fnp-4682	160	28	,	,	PUNCT
fnp-4682	160	29	small	small	ADJ
fnp-4682	160	30	arrowheads	arrowhead	NOUN
fnp-4682	160	31	)	)	PUNCT
fnp-4682	160	32	at	at	ADP
fnp-4682	160	33	the	the	DET
fnp-4682	160	34	axo	axo	NOUN
fnp-4682	160	35	-	-	PUNCT
fnp-4682	160	36	glial	glial	ADJ
fnp-4682	160	37	junction	junction	NOUN
fnp-4682	160	38	between	between	ADP
fnp-4682	160	39	the	the	DET
fnp-4682	160	40	axon	axon	NOUN
fnp-4682	160	41	and	and	CCONJ
fnp-4682	160	42	paranodal	paranodal	ADJ
fnp-4682	160	43	loops	loop	NOUN
fnp-4682	160	44	.	.	PUNCT
fnp-4682	161	1	(	(	PUNCT
fnp-4682	161	2	c	c	X
fnp-4682	161	3	)	)	PUNCT
fnp-4682	161	4	injured	injure	VERB
fnp-4682	161	5	glial	glial	ADJ
fnp-4682	161	6	nors	nor	NOUN
fnp-4682	161	7	show	show	VERB
fnp-4682	161	8	severely	severely	ADV
fnp-4682	161	9	disrupted	disrupt	VERB
fnp-4682	161	10	paranodal	paranodal	ADJ
fnp-4682	161	11	loop	loop	NOUN
fnp-4682	161	12	organization	organization	NOUN
fnp-4682	161	13	compared	compare	VERB
fnp-4682	161	14	with	with	ADP
fnp-4682	161	15	control	control	NOUN
fnp-4682	161	16	.	.	PUNCT
fnp-4682	162	1	(	(	PUNCT
fnp-4682	162	2	d	d	X
fnp-4682	162	3	)	)	PUNCT
fnp-4682	162	4	magnification	magnification	NOUN
fnp-4682	162	5	of	of	ADP
fnp-4682	162	6	boxed	boxed	ADJ
fnp-4682	162	7	area	area	NOUN
fnp-4682	162	8	from	from	ADP
fnp-4682	162	9	c	c	PROPN
fnp-4682	162	10	,	,	PUNCT
fnp-4682	162	11	shows	show	VERB
fnp-4682	162	12	tbs	tbs	NOUN
fnp-4682	162	13	are	be	AUX
fnp-4682	162	14	present	present	ADJ
fnp-4682	162	15	between	between	ADP
fnp-4682	162	16	the	the	DET
fnp-4682	162	17	paranodal	paranodal	ADJ
fnp-4682	162	18	loops	loop	NOUN
fnp-4682	162	19	and	and	CCONJ
fnp-4682	162	20	axon	axon	NOUN
fnp-4682	162	21	at	at	ADP
fnp-4682	162	22	the	the	DET
fnp-4682	162	23	juxtaparanodal	juxtaparanodal	ADJ
fnp-4682	162	24	-	-	ADJ
fnp-4682	162	25	proximal	proximal	ADJ
fnp-4682	162	26	paranode	paranode	NOUN
fnp-4682	162	27	(	(	PUNCT
fnp-4682	162	28	above	above	ADP
fnp-4682	162	29	black	black	ADJ
fnp-4682	162	30	line	line	NOUN
fnp-4682	162	31	)	)	PUNCT
fnp-4682	162	32	;	;	PUNCT
fnp-4682	162	33	however	however	ADV
fnp-4682	162	34	,	,	PUNCT
fnp-4682	162	35	they	they	PRON
fnp-4682	162	36	are	be	AUX
fnp-4682	162	37	absent	absent	ADJ
fnp-4682	162	38	at	at	ADP
fnp-4682	162	39	the	the	DET
fnp-4682	162	40	node	node	NOUN
fnp-4682	162	41	-	-	PUNCT
fnp-4682	162	42	proximal	proximal	ADJ
fnp-4682	162	43	border	border	NOUN
fnp-4682	162	44	(	(	PUNCT
fnp-4682	162	45	above	above	ADP
fnp-4682	162	46	white	white	ADJ
fnp-4682	162	47	line	line	NOUN
fnp-4682	162	48	,	,	PUNCT
fnp-4682	162	49	right	right	NOUN
fnp-4682	162	50	of	of	ADP
fnp-4682	162	51	asterisk	asterisk	NOUN
fnp-4682	162	52	)	)	PUNCT
fnp-4682	162	53	.	.	PUNCT
fnp-4682	163	1	(	(	PUNCT
fnp-4682	163	2	e	e	X
fnp-4682	163	3	)	)	PUNCT
fnp-4682	163	4	injured	injure	VERB
fnp-4682	163	5	neuronal	neuronal	ADJ
fnp-4682	163	6	nors	nor	NOUN
fnp-4682	163	7	show	show	VERB
fnp-4682	163	8	no	no	DET
fnp-4682	163	9	architectural	architectural	ADJ
fnp-4682	163	10	disruption	disruption	NOUN
fnp-4682	163	11	.	.	PUNCT
fnp-4682	164	1	(	(	PUNCT
fnp-4682	164	2	f	f	X
fnp-4682	164	3	)	)	PUNCT
fnp-4682	164	4	neuronal	neuronal	ADJ
fnp-4682	164	5	control	control	NOUN
fnp-4682	164	6	motor	motor	PROPN
fnp-4682	164	7	nerve	nerve	NOUN
fnp-4682	164	8	terminal	terminal	NOUN
fnp-4682	164	9	(	(	PUNCT
fnp-4682	164	10	mnt	mnt	NOUN
fnp-4682	164	11	)	)	PUNCT
fnp-4682	164	12	displays	display	VERB
fnp-4682	164	13	normal	normal	ADJ
fnp-4682	164	14	architecture	architecture	NOUN
fnp-4682	164	15	and	and	CCONJ
fnp-4682	164	16	contains	contain	VERB
fnp-4682	164	17	synaptic	synaptic	ADJ
fnp-4682	164	18	vesicles	vesicle	NOUN
fnp-4682	164	19	(	(	PUNCT
fnp-4682	164	20	black	black	ADJ
fnp-4682	164	21	arrows	arrow	NOUN
fnp-4682	164	22	)	)	PUNCT
fnp-4682	164	23	.	.	PUNCT
fnp-4682	165	1	(	(	PUNCT
fnp-4682	165	2	g	g	NOUN
fnp-4682	165	3	)	)	PUNCT
fnp-4682	165	4	disturbance	disturbance	NOUN
fnp-4682	165	5	to	to	ADP
fnp-4682	165	6	the	the	DET
fnp-4682	165	7	injured	injure	VERB
fnp-4682	165	8	neuronal	neuronal	ADJ
fnp-4682	165	9	mnt	mnt	NOUN
fnp-4682	165	10	includes	include	VERB
fnp-4682	165	11	an	an	DET
fnp-4682	165	12	absence	absence	NOUN
fnp-4682	165	13	of	of	ADP
fnp-4682	165	14	neurofilament	neurofilament	NOUN
fnp-4682	165	15	,	,	PUNCT
fnp-4682	165	16	synaptic	synaptic	ADJ
fnp-4682	165	17	vesicles	vesicle	NOUN
fnp-4682	165	18	,	,	PUNCT
fnp-4682	165	19	and	and	CCONJ
fnp-4682	165	20	the	the	DET
fnp-4682	165	21	formation	formation	NOUN
fnp-4682	165	22	of	of	ADP
fnp-4682	165	23	dense	dense	ADJ
fnp-4682	165	24	or	or	CCONJ
fnp-4682	165	25	vacuolated	vacuolated	ADJ
fnp-4682	165	26	mitochondria	mitochondria	NOUN
fnp-4682	165	27	(	(	PUNCT
fnp-4682	165	28	white	white	ADJ
fnp-4682	165	29	arrows	arrow	NOUN
fnp-4682	165	30	)	)	PUNCT
fnp-4682	165	31	.	.	PUNCT
fnp-4682	166	1	results	result	NOUN
fnp-4682	166	2	are	be	AUX
fnp-4682	166	3	representative	representative	ADJ
fnp-4682	166	4	of	of	ADP
fnp-4682	166	5	analysis	analysis	NOUN
fnp-4682	166	6	from	from	ADP
fnp-4682	166	7	8–10	8–10	NOUN
fnp-4682	166	8	nors	nor	NOUN
fnp-4682	166	9	per	per	ADP
fnp-4682	166	10	mouse	mouse	NOUN
fnp-4682	166	11	(	(	PUNCT
fnp-4682	166	12	n	n	NOUN
fnp-4682	166	13	=	=	SYM
fnp-4682	166	14	3	3	NUM
fnp-4682	166	15	/	/	SYM
fnp-4682	166	16	genotype	genotype	NOUN
fnp-4682	166	17	/	/	SYM
fnp-4682	166	18	treatment	treatment	NOUN
fnp-4682	166	19	)	)	PUNCT
fnp-4682	166	20	.	.	PUNCT
fnp-4682	167	1	[	[	X
fnp-4682	167	2	this	this	DET
fnp-4682	167	3	figure	figure	NOUN
fnp-4682	167	4	and	and	CCONJ
fnp-4682	167	5	its	its	PRON
fnp-4682	167	6	legend	legend	NOUN
fnp-4682	167	7	were	be	AUX
fnp-4682	167	8	adopted	adopt	VERB
fnp-4682	167	9	from	from	ADP
fnp-4682	167	10	figure	figure	NOUN
fnp-4682	167	11	6	6	NUM
fnp-4682	167	12	in	in	ADP
fnp-4682	167	13	(	(	PUNCT
fnp-4682	167	14	mcgonigal	mcgonigal	PROPN
fnp-4682	167	15	et	et	PROPN
fnp-4682	167	16	al	al	PROPN
fnp-4682	167	17	.	.	PROPN
fnp-4682	167	18	,	,	PUNCT
fnp-4682	167	19	2022	2022	NUM
fnp-4682	167	20	)	)	PUNCT
fnp-4682	167	21	;	;	PUNCT
fnp-4682	167	22	this	this	DET
fnp-4682	167	23	use	use	NOUN
fnp-4682	167	24	is	be	AUX
fnp-4682	167	25	permitted	permit	VERB
fnp-4682	167	26	under	under	ADP
fnp-4682	167	27	the	the	DET
fnp-4682	167	28	creative	creative	ADJ
fnp-4682	167	29	commons	common	NOUN
fnp-4682	167	30	attribution	attribution	NOUN
fnp-4682	167	31	4.0	4.0	NUM
fnp-4682	167	32	cc	cc	NOUN
fnp-4682	167	33	-	-	PUNCT
fnp-4682	167	34	by	by	ADP
fnp-4682	167	35	international	international	ADJ
fnp-4682	167	36	license	license	NOUN
fnp-4682	167	37	.	.	PUNCT
fnp-4682	168	1	]	]	X
fnp-4682	168	2	what	what	PRON
fnp-4682	168	3	is	be	AUX
fnp-4682	168	4	the	the	DET
fnp-4682	168	5	relevance	relevance	NOUN
fnp-4682	168	6	of	of	ADP
fnp-4682	168	7	these	these	DET
fnp-4682	168	8	findings	finding	NOUN
fnp-4682	168	9	for	for	ADP
fnp-4682	168	10	human	human	PROPN
fnp-4682	168	11	gbs	gbs	PROPN
fnp-4682	168	12	?	?	PUNCT
fnp-4682	169	1	since	since	SCONJ
fnp-4682	169	2	gm1	gm1	PROPN
fnp-4682	169	3	gangliosides	ganglioside	NOUN
fnp-4682	169	4	(	(	PUNCT
fnp-4682	169	5	and	and	CCONJ
fnp-4682	169	6	other	other	ADJ
fnp-4682	169	7	ganglioside	ganglioside	NOUN
fnp-4682	169	8	antigens	antigen	NOUN
fnp-4682	169	9	)	)	PUNCT
fnp-4682	169	10	are	be	AUX
fnp-4682	169	11	expressed	express	VERB
fnp-4682	169	12	by	by	ADP
fnp-4682	169	13	neurons	neuron	NOUN
fnp-4682	169	14	as	as	ADV
fnp-4682	169	15	well	well	ADV
fnp-4682	169	16	as	as	ADP
fnp-4682	169	17	scs	scs	PROPN
fnp-4682	169	18	,	,	PUNCT
fnp-4682	169	19	both	both	PRON
fnp-4682	169	20	of	of	ADP
fnp-4682	169	21	these	these	DET
fnp-4682	169	22	mechanisms	mechanism	NOUN
fnp-4682	169	23	are	be	AUX
fnp-4682	169	24	likely	likely	ADJ
fnp-4682	169	25	in	in	ADP
fnp-4682	169	26	play	play	NOUN
fnp-4682	169	27	in	in	ADP
fnp-4682	169	28	human	human	ADJ
fnp-4682	169	29	disease	disease	NOUN
fnp-4682	169	30	,	,	PUNCT
fnp-4682	169	31	and	and	CCONJ
fnp-4682	169	32	which	which	DET
fnp-4682	169	33	mechanism	mechanism	NOUN
fnp-4682	169	34	dominates	dominate	VERB
fnp-4682	169	35	in	in	ADP
fnp-4682	169	36	any	any	DET
fnp-4682	169	37	given	give	VERB
fnp-4682	169	38	gbs	gbs	PROPN
fnp-4682	169	39	patient	patient	NOUN
fnp-4682	169	40	likely	likely	ADV
fnp-4682	169	41	depends	depend	VERB
fnp-4682	169	42	on	on	ADP
fnp-4682	169	43	a	a	DET
fnp-4682	169	44	combination	combination	NOUN
fnp-4682	169	45	of	of	ADP
fnp-4682	169	46	factors	factor	NOUN
fnp-4682	169	47	,	,	PUNCT
fnp-4682	169	48	including	include	VERB
fnp-4682	169	49	antibody	antibody	NOUN
fnp-4682	169	50	titer	titer	NOUN
fnp-4682	169	51	/	/	SYM
fnp-4682	169	52	specificity	specificity	NOUN
fnp-4682	169	53	and	and	CCONJ
fnp-4682	169	54	intrinsic	intrinsic	ADJ
fnp-4682	169	55	host	host	NOUN
fnp-4682	169	56	factors	factor	NOUN
fnp-4682	169	57	that	that	PRON
fnp-4682	169	58	shape	shape	VERB
fnp-4682	169	59	disease	disease	NOUN
fnp-4682	169	60	vulnerability	vulnerability	NOUN
fnp-4682	169	61	.	.	PUNCT
fnp-4682	170	1	moreover	moreover	ADV
fnp-4682	170	2	,	,	PUNCT
fnp-4682	170	3	these	these	DET
fnp-4682	170	4	findings	finding	NOUN
fnp-4682	170	5	have	have	VERB
fnp-4682	170	6	potential	potential	ADJ
fnp-4682	170	7	diagnostic	diagnostic	ADJ
fnp-4682	170	8	implications	implication	NOUN
fnp-4682	170	9	:	:	PUNCT
fnp-4682	170	10	taken	take	VERB
fnp-4682	170	11	together	together	ADV
fnp-4682	170	12	with	with	ADP
fnp-4682	170	13	the	the	DET
fnp-4682	170	14	2020	2020	NUM
fnp-4682	170	15	ultrastructural	ultrastructural	ADJ
fnp-4682	170	16	study	study	NOUN
fnp-4682	170	17	of	of	ADP
fnp-4682	170	18	peripheral	peripheral	ADJ
fnp-4682	170	19	nerves	nerve	NOUN
fnp-4682	170	20	from	from	ADP
fnp-4682	170	21	patients	patient	NOUN
fnp-4682	170	22	with	with	ADP
fnp-4682	170	23	gbs	gbs	PROPN
fnp-4682	170	24	and	and	CCONJ
fnp-4682	170	25	other	other	ADJ
fnp-4682	170	26	nodo	nodo	NOUN
fnp-4682	170	27	-	-	PUNCT
fnp-4682	170	28	paranodopathies	paranodopathie	NOUN
fnp-4682	170	29	(	(	PUNCT
fnp-4682	170	30	vallat	vallat	X
fnp-4682	170	31	et	et	NOUN
fnp-4682	170	32	al	al	PROPN
fnp-4682	170	33	.	.	PROPN
fnp-4682	170	34	,	,	PUNCT
fnp-4682	170	35	2020	2020	NUM
fnp-4682	170	36	)	)	PUNCT
fnp-4682	170	37	,	,	PUNCT
fnp-4682	170	38	which	which	PRON
fnp-4682	170	39	showed	show	VERB
fnp-4682	170	40	ultrastructural	ultrastructural	ADJ
fnp-4682	170	41	nodal	nodal	NOUN
fnp-4682	170	42	pathology	pathology	NOUN
fnp-4682	170	43	similar	similar	ADJ
fnp-4682	170	44	to	to	ADP
fnp-4682	170	45	ultrastructural	ultrastructural	ADJ
fnp-4682	170	46	abnormalities	abnormality	NOUN
fnp-4682	170	47	seen	see	VERB
fnp-4682	170	48	in	in	ADP
fnp-4682	170	49	glial	glial	ADJ
fnp-4682	170	50	gbs	gbs	PROPN
fnp-4682	170	51	mice	mice	NOUN
fnp-4682	170	52	(	(	PUNCT
fnp-4682	170	53	fig	fig	NOUN
fnp-4682	170	54	.	.	PUNCT
fnp-4682	171	1	4	4	NUM
fnp-4682	171	2	)	)	PUNCT
fnp-4682	171	3	,	,	PUNCT
fnp-4682	171	4	they	they	PRON
fnp-4682	171	5	suggest	suggest	VERB
fnp-4682	171	6	that	that	SCONJ
fnp-4682	171	7	electron	electron	NOUN
fnp-4682	171	8	microscopic	microscopic	ADJ
fnp-4682	171	9	evaluation	evaluation	NOUN
fnp-4682	171	10	of	of	ADP
fnp-4682	171	11	nor	nor	CCONJ
fnp-4682	171	12	could	could	AUX
fnp-4682	171	13	help	help	VERB
fnp-4682	171	14	delineate	delineate	VERB
fnp-4682	171	15	immune	immune	NOUN
fnp-4682	171	16	-	-	PUNCT
fnp-4682	171	17	mediated	mediate	VERB
fnp-4682	171	18	from	from	ADP
fnp-4682	171	19	ischemic	ischemic	ADJ
fnp-4682	171	20	and	and	CCONJ
fnp-4682	171	21	other	other	ADJ
fnp-4682	171	22	causes	cause	NOUN
fnp-4682	171	23	of	of	ADP
fnp-4682	171	24	axonal	axonal	ADJ
fnp-4682	171	25	injury	injury	NOUN
fnp-4682	171	26	,	,	PUNCT
fnp-4682	171	27	and	and	CCONJ
fnp-4682	171	28	should	should	AUX
fnp-4682	171	29	therefore	therefore	ADV
fnp-4682	171	30	be	be	AUX
fnp-4682	171	31	included	include	VERB
fnp-4682	171	32	in	in	ADP
fnp-4682	171	33	the	the	DET
fnp-4682	171	34	nerve	nerve	NOUN
fnp-4682	171	35	biopsy	biopsy	NOUN
fnp-4682	171	36	workup	workup	PROPN
fnp-4682	171	37	whenever	whenever	SCONJ
fnp-4682	171	38	an	an	DET
fnp-4682	171	39	obvious	obvious	ADJ
fnp-4682	171	40	cause	cause	NOUN
fnp-4682	171	41	of	of	ADP
fnp-4682	171	42	axon	axon	NOUN
fnp-4682	171	43	degeneration	degeneration	NOUN
fnp-4682	171	44	(	(	PUNCT
fnp-4682	171	45	such	such	ADJ
fnp-4682	171	46	as	as	ADP
fnp-4682	171	47	vasculitis	vasculiti	NOUN
fnp-4682	171	48	)	)	PUNCT
fnp-4682	171	49	is	be	AUX
fnp-4682	171	50	not	not	PART
fnp-4682	171	51	detected	detect	VERB
fnp-4682	171	52	in	in	ADP
fnp-4682	171	53	a	a	DET
fnp-4682	171	54	nerve	nerve	NOUN
fnp-4682	171	55	biopsy	biopsy	NOUN
fnp-4682	171	56	.	.	PUNCT
fnp-4682	172	1	6	6	X
fnp-4682	172	2	.	.	X
fnp-4682	172	3	target	target	NOUN
fnp-4682	172	4	formation	formation	NOUN
fnp-4682	172	5	is	be	AUX
fnp-4682	172	6	indicative	indicative	ADJ
fnp-4682	172	7	of	of	ADP
fnp-4682	172	8	muscle	muscle	NOUN
fnp-4682	172	9	fiber	fiber	NOUN
fnp-4682	172	10	reinnervation	reinnervation	NOUN
fnp-4682	172	11	target	target	NOUN
fnp-4682	172	12	fibers	fiber	NOUN
fnp-4682	172	13	are	be	AUX
fnp-4682	172	14	one	one	NUM
fnp-4682	172	15	of	of	ADP
fnp-4682	172	16	the	the	DET
fnp-4682	172	17	classic	classic	ADJ
fnp-4682	172	18	diagnostic	diagnostic	ADJ
fnp-4682	172	19	features	feature	NOUN
fnp-4682	172	20	of	of	ADP
fnp-4682	172	21	a	a	DET
fnp-4682	172	22	neurogenic	neurogenic	ADJ
fnp-4682	172	23	change	change	NOUN
fnp-4682	172	24	secondary	secondary	ADJ
fnp-4682	172	25	to	to	ADP
fnp-4682	172	26	lower	low	ADJ
fnp-4682	172	27	motor	motor	NOUN
fnp-4682	172	28	neuron	neuron	NOUN
fnp-4682	172	29	(	(	PUNCT
fnp-4682	172	30	lmn	lmn	PROPN
fnp-4682	172	31	)	)	PUNCT
fnp-4682	172	32	injury	injury	NOUN
fnp-4682	172	33	.	.	PUNCT
fnp-4682	173	1	targets	target	NOUN
fnp-4682	173	2	are	be	AUX
fnp-4682	173	3	most	most	ADV
fnp-4682	173	4	commonly	commonly	ADV
fnp-4682	173	5	seen	see	VERB
fnp-4682	173	6	in	in	ADP
fnp-4682	173	7	type	type	NOUN
fnp-4682	173	8	1	1	NUM
fnp-4682	173	9	fibers	fiber	NOUN
fnp-4682	173	10	,	,	PUNCT
fnp-4682	173	11	are	be	AUX
fnp-4682	173	12	best	well	ADV
fnp-4682	173	13	visualized	visualize	VERB
fnp-4682	173	14	on	on	ADP
fnp-4682	173	15	oxidative	oxidative	ADJ
fnp-4682	173	16	stains	stain	NOUN
fnp-4682	173	17	,	,	PUNCT
fnp-4682	173	18	and	and	CCONJ
fnp-4682	173	19	in	in	ADP
fnp-4682	173	20	the	the	DET
fnp-4682	173	21	cross	cross	ADJ
fnp-4682	173	22	-	-	ADJ
fnp-4682	173	23	sectional	sectional	ADJ
fnp-4682	173	24	view	view	NOUN
fnp-4682	173	25	consist	consist	NOUN
fnp-4682	173	26	of	of	ADP
fnp-4682	173	27	several	several	ADJ
fnp-4682	173	28	distinct	distinct	ADJ
fnp-4682	173	29	concentric	concentric	ADJ
fnp-4682	173	30	layers	layer	NOUN
fnp-4682	173	31	/	/	SYM
fnp-4682	173	32	zones	zone	NOUN
fnp-4682	173	33	–	–	PUNCT
fnp-4682	173	34	typically	typically	ADV
fnp-4682	173	35	a	a	DET
fnp-4682	173	36	central	central	ADJ
fnp-4682	173	37	pale	pale	ADJ
fnp-4682	173	38	area	area	NOUN
fnp-4682	173	39	devoid	devoid	ADJ
fnp-4682	173	40	of	of	ADP
fnp-4682	173	41	mitochondrial	mitochondrial	ADJ
fnp-4682	173	42	activity	activity	NOUN
fnp-4682	173	43	and	and	CCONJ
fnp-4682	173	44	reminiscent	reminiscent	ADJ
fnp-4682	173	45	of	of	ADP
fnp-4682	173	46	a	a	DET
fnp-4682	173	47	core	core	NOUN
fnp-4682	173	48	,	,	PUNCT
fnp-4682	173	49	an	an	DET
fnp-4682	173	50	intermediate	intermediate	ADJ
fnp-4682	173	51	zone	zone	NOUN
fnp-4682	173	52	that	that	PRON
fnp-4682	173	53	shows	show	VERB
fnp-4682	173	54	a	a	DET
fnp-4682	173	55	decreased	decrease	VERB
fnp-4682	173	56	but	but	CCONJ
fnp-4682	173	57	not	not	PART
fnp-4682	173	58	entirely	entirely	ADV
fnp-4682	173	59	absent	absent	ADJ
fnp-4682	173	60	mitochondrial	mitochondrial	ADJ
fnp-4682	173	61	activity	activity	NOUN
fnp-4682	173	62	,	,	PUNCT
fnp-4682	173	63	and	and	CCONJ
fnp-4682	173	64	an	an	DET
fnp-4682	173	65	outer	outer	ADJ
fnp-4682	173	66	zone	zone	NOUN
fnp-4682	173	67	that	that	PRON
fnp-4682	173	68	resembles	resemble	VERB
fnp-4682	173	69	the	the	DET
fnp-4682	173	70	rest	rest	NOUN
fnp-4682	173	71	of	of	ADP
fnp-4682	173	72	the	the	DET
fnp-4682	173	73	myofiber	myofiber	NOUN
fnp-4682	173	74	and	and	CCONJ
fnp-4682	173	75	often	often	ADV
fnp-4682	173	76	shows	show	VERB
fnp-4682	173	77	an	an	DET
fnp-4682	173	78	increase	increase	NOUN
fnp-4682	173	79	in	in	ADP
fnp-4682	173	80	mitochondrial	mitochondrial	ADJ
fnp-4682	173	81	activity	activity	NOUN
fnp-4682	173	82	(	(	PUNCT
fnp-4682	173	83	fig	fig	NOUN
fnp-4682	173	84	.	.	PUNCT
fnp-4682	174	1	5a	5a	NUM
fnp-4682	174	2	-	-	PUNCT
fnp-4682	174	3	b	b	NOUN
fnp-4682	174	4	)	)	PUNCT
fnp-4682	174	5	.	.	PUNCT
fnp-4682	175	1	ultrastructurally	ultrastructurally	ADV
fnp-4682	175	2	,	,	PUNCT
fnp-4682	175	3	the	the	DET
fnp-4682	175	4	central	central	ADJ
fnp-4682	175	5	zone	zone	NOUN
fnp-4682	175	6	contains	contain	VERB
fnp-4682	175	7	the	the	DET
fnp-4682	175	8	z	z	NOUN
fnp-4682	175	9	-	-	PUNCT
fnp-4682	175	10	disc	disc	NOUN
fnp-4682	175	11	material	material	NOUN
fnp-4682	175	12	and	and	CCONJ
fnp-4682	175	13	is	be	AUX
fnp-4682	175	14	devoid	devoid	ADJ
fnp-4682	175	15	of	of	ADP
fnp-4682	175	16	glycogen	glycogen	NOUN
fnp-4682	175	17	and	and	CCONJ
fnp-4682	175	18	mitochondria	mitochondria	PROPN
fnp-4682	175	19	,	,	PUNCT
fnp-4682	175	20	the	the	DET
fnp-4682	175	21	intermediate	intermediate	ADJ
fnp-4682	175	22	zone	zone	NOUN
fnp-4682	175	23	shows	show	VERB
fnp-4682	175	24	disorganized	disorganized	ADJ
fnp-4682	175	25	myofilaments	myofilament	NOUN
fnp-4682	175	26	with	with	ADP
fnp-4682	175	27	mild	mild	ADJ
fnp-4682	175	28	z	z	NOUN
fnp-4682	175	29	-	-	PUNCT
fnp-4682	175	30	line	line	NOUN
fnp-4682	175	31	abnormalities	abnormality	NOUN
fnp-4682	175	32	,	,	PUNCT
fnp-4682	175	33	while	while	SCONJ
fnp-4682	175	34	the	the	DET
fnp-4682	175	35	outer	outer	ADJ
fnp-4682	175	36	zone	zone	NOUN
fnp-4682	175	37	contains	contain	VERB
fnp-4682	175	38	ultrastructurally	ultrastructurally	ADV
fnp-4682	175	39	normal	normal	ADJ
fnp-4682	175	40	myofilaments	myofilament	NOUN
fnp-4682	175	41	.	.	PUNCT
fnp-4682	176	1	similar	similar	ADJ
fnp-4682	176	2	formations	formation	NOUN
fnp-4682	176	3	that	that	PRON
fnp-4682	176	4	have	have	VERB
fnp-4682	176	5	a	a	DET
fnp-4682	176	6	less	less	ADV
fnp-4682	176	7	distinctively	distinctively	ADV
fnp-4682	176	8	layered	layered	ADJ
fnp-4682	176	9	appearance	appearance	NOUN
fnp-4682	176	10	are	be	AUX
fnp-4682	176	11	called	call	VERB
fnp-4682	176	12	“	"	PUNCT
fnp-4682	176	13	targetoid	targetoid	NOUN
fnp-4682	176	14	”	"	PUNCT
fnp-4682	176	15	and	and	CCONJ
fnp-4682	176	16	can	can	AUX
fnp-4682	176	17	be	be	AUX
fnp-4682	176	18	more	more	ADV
fnp-4682	176	19	difficult	difficult	ADJ
fnp-4682	176	20	to	to	PART
fnp-4682	176	21	distinguish	distinguish	VERB
fnp-4682	176	22	from	from	ADP
fnp-4682	176	23	cores	core	NOUN
fnp-4682	176	24	if	if	SCONJ
fnp-4682	176	25	they	they	PRON
fnp-4682	176	26	are	be	AUX
fnp-4682	176	27	not	not	PART
fnp-4682	176	28	accompanied	accompany	VERB
fnp-4682	176	29	by	by	ADP
fnp-4682	176	30	true	true	ADJ
fnp-4682	176	31	targets	target	NOUN
fnp-4682	176	32	and/or	and/or	CCONJ
fnp-4682	176	33	other	other	ADJ
fnp-4682	176	34	diagnostic	diagnostic	ADJ
fnp-4682	176	35	features	feature	NOUN
fnp-4682	176	36	of	of	ADP
fnp-4682	176	37	neurogenic	neurogenic	ADJ
fnp-4682	176	38	change	change	NOUN
fnp-4682	176	39	.	.	PUNCT
fnp-4682	177	1	however	however	ADV
fnp-4682	177	2	,	,	PUNCT
fnp-4682	177	3	targets	target	NOUN
fnp-4682	177	4	are	be	AUX
fnp-4682	177	5	not	not	PART
fnp-4682	177	6	present	present	ADJ
fnp-4682	177	7	in	in	ADP
fnp-4682	177	8	all	all	DET
fnp-4682	177	9	muscle	muscle	NOUN
fnp-4682	177	10	biopsies	biopsy	NOUN
fnp-4682	177	11	with	with	ADP
fnp-4682	177	12	neuropathic	neuropathic	ADJ
fnp-4682	177	13	changes	change	NOUN
fnp-4682	177	14	,	,	PUNCT
fnp-4682	177	15	and	and	CCONJ
fnp-4682	177	16	can	can	AUX
fnp-4682	177	17	be	be	AUX
fnp-4682	177	18	seen	see	VERB
fnp-4682	177	19	both	both	CCONJ
fnp-4682	177	20	in	in	ADP
fnp-4682	177	21	small	small	ADJ
fnp-4682	177	22	angulated	angulate	VERB
fnp-4682	177	23	and	and	CCONJ
fnp-4682	177	24	normally	normally	ADV
fnp-4682	177	25	sized	sized	ADJ
fnp-4682	177	26	fibers	fiber	NOUN
fnp-4682	177	27	.	.	PUNCT
fnp-4682	178	1	as	as	ADP
fnp-4682	178	2	a	a	DET
fnp-4682	178	3	result	result	NOUN
fnp-4682	178	4	,	,	PUNCT
fnp-4682	178	5	it	it	PRON
fnp-4682	178	6	has	have	AUX
fnp-4682	178	7	been	be	AUX
fnp-4682	178	8	unclear	unclear	ADJ
fnp-4682	178	9	whether	whether	SCONJ
fnp-4682	178	10	target	target	NOUN
fnp-4682	178	11	formation	formation	NOUN
fnp-4682	178	12	reflects	reflect	VERB
fnp-4682	178	13	denervation	denervation	NOUN
fnp-4682	178	14	[	[	PUNCT
fnp-4682	178	15	as	as	SCONJ
fnp-4682	178	16	originally	originally	ADV
fnp-4682	178	17	proposed	propose	VERB
fnp-4682	178	18	(	(	PUNCT
fnp-4682	178	19	engel	engel	PROPN
fnp-4682	178	20	,	,	PUNCT
fnp-4682	178	21	1961	1961	NUM
fnp-4682	178	22	)	)	PUNCT
fnp-4682	178	23	]	]	PUNCT
fnp-4682	178	24	or	or	CCONJ
fnp-4682	178	25	reinnervation	reinnervation	NOUN
fnp-4682	178	26	[	[	PUNCT
fnp-4682	178	27	as	as	SCONJ
fnp-4682	178	28	suggested	suggest	VERB
fnp-4682	178	29	by	by	ADP
fnp-4682	178	30	subsequent	subsequent	ADJ
fnp-4682	178	31	animal	animal	NOUN
fnp-4682	178	32	model	model	NOUN
fnp-4682	178	33	studies	study	NOUN
fnp-4682	178	34	(	(	PUNCT
fnp-4682	178	35	de	de	X
fnp-4682	178	36	reuck	reuck	NOUN
fnp-4682	178	37	et	et	PROPN
fnp-4682	178	38	al	al	PROPN
fnp-4682	178	39	.	.	PROPN
fnp-4682	178	40	,	,	PUNCT
fnp-4682	178	41	1977	1977	NUM
fnp-4682	178	42	)	)	PUNCT
fnp-4682	178	43	]	]	PUNCT
fnp-4682	178	44	.	.	PUNCT
fnp-4682	179	1	a	a	DET
fnp-4682	179	2	recent	recent	ADJ
fnp-4682	179	3	proteomic	proteomic	ADJ
fnp-4682	179	4	study	study	NOUN
fnp-4682	179	5	done	do	VERB
fnp-4682	179	6	by	by	ADP
fnp-4682	179	7	the	the	DET
fnp-4682	179	8	kley	kley	PROPN
fnp-4682	179	9	lab	lab	NOUN
fnp-4682	179	10	sheds	shed	VERB
fnp-4682	179	11	a	a	DET
fnp-4682	179	12	new	new	ADJ
fnp-4682	179	13	light	light	NOUN
fnp-4682	179	14	on	on	ADP
fnp-4682	179	15	this	this	DET
fnp-4682	179	16	old	old	ADJ
fnp-4682	179	17	question	question	NOUN
fnp-4682	179	18	,	,	PUNCT
fnp-4682	179	19	providing	provide	VERB
fnp-4682	179	20	compelling	compelling	ADJ
fnp-4682	179	21	evidence	evidence	NOUN
fnp-4682	179	22	that	that	PRON
fnp-4682	179	23	target	target	VERB
fnp-4682	179	24	formation	formation	NOUN
fnp-4682	179	25	reflects	reflect	VERB
fnp-4682	179	26	myofibril	myofibril	NOUN
fnp-4682	179	27	assembly	assembly	NOUN
fnp-4682	179	28	that	that	PRON
fnp-4682	179	29	occurs	occur	VERB
fnp-4682	179	30	following	follow	VERB
fnp-4682	179	31	reinnervation	reinnervation	NOUN
fnp-4682	179	32	(	(	PUNCT
fnp-4682	179	33	krause	krause	PROPN
fnp-4682	179	34	et	et	PROPN
fnp-4682	179	35	al	al	PROPN
fnp-4682	179	36	.	.	PROPN
fnp-4682	179	37	,	,	PUNCT
fnp-4682	179	38	2022	2022	NUM
fnp-4682	179	39	)	)	PUNCT
fnp-4682	179	40	.	.	PUNCT
fnp-4682	180	1	figure	figure	NOUN
fnp-4682	180	2	5	5	NUM
fnp-4682	180	3	.	.	PUNCT
fnp-4682	180	4	target	target	NOUN
fnp-4682	180	5	fibers	fiber	NOUN
fnp-4682	180	6	.	.	PUNCT
fnp-4682	181	1	(	(	PUNCT
fnp-4682	181	2	a	a	PRON
fnp-4682	181	3	)	)	PUNCT
fnp-4682	181	4	nadh	nadh	NOUN
fnp-4682	181	5	-	-	PUNCT
fnp-4682	181	6	tr	tr	VERB
fnp-4682	181	7	stain	stain	NOUN
fnp-4682	181	8	shows	show	VERB
fnp-4682	181	9	two	two	NUM
fnp-4682	181	10	type	type	NOUN
fnp-4682	181	11	1	1	NUM
fnp-4682	181	12	fibers	fiber	NOUN
fnp-4682	181	13	with	with	ADP
fnp-4682	181	14	central	central	ADJ
fnp-4682	181	15	target	target	NOUN
fnp-4682	181	16	formations	formation	NOUN
fnp-4682	181	17	;	;	PUNCT
fnp-4682	181	18	on	on	ADP
fnp-4682	181	19	myosin	myosin	PROPN
fnp-4682	181	20	heavy	heavy	PROPN
fnp-4682	181	21	chain	chain	NOUN
fnp-4682	181	22	immunohistochemistry	immunohistochemistry	NOUN
fnp-4682	181	23	,	,	PUNCT
fnp-4682	181	24	these	these	DET
fnp-4682	181	25	fibers	fiber	NOUN
fnp-4682	181	26	were	be	AUX
fnp-4682	181	27	positive	positive	ADJ
fnp-4682	181	28	for	for	ADP
fnp-4682	181	29	myhc	myhc	NOUN
fnp-4682	181	30	-	-	PUNCT
fnp-4682	181	31	slow	slow	NOUN
fnp-4682	181	32	(	(	PUNCT
fnp-4682	181	33	mhc7	mhc7	PROPN
fnp-4682	181	34	;	;	PUNCT
fnp-4682	181	35	not	not	PART
fnp-4682	181	36	shown	show	VERB
fnp-4682	181	37	)	)	PUNCT
fnp-4682	181	38	.	.	PUNCT
fnp-4682	182	1	the	the	DET
fnp-4682	182	2	same	same	ADJ
fnp-4682	182	3	microscopic	microscopic	ADJ
fnp-4682	182	4	field	field	NOUN
fnp-4682	182	5	,	,	PUNCT
fnp-4682	182	6	captured	capture	VERB
fnp-4682	182	7	on	on	ADP
fnp-4682	182	8	consecutive	consecutive	ADJ
fnp-4682	182	9	cryosections	cryosection	NOUN
fnp-4682	182	10	,	,	PUNCT
fnp-4682	182	11	is	be	AUX
fnp-4682	182	12	shown	show	VERB
fnp-4682	182	13	in	in	ADP
fnp-4682	182	14	all	all	DET
fnp-4682	182	15	main	main	ADJ
fnp-4682	182	16	figure	figure	NOUN
fnp-4682	182	17	panels	panel	NOUN
fnp-4682	182	18	;	;	PUNCT
fnp-4682	182	19	target	target	NOUN
fnp-4682	182	20	formations	formation	NOUN
fnp-4682	182	21	are	be	AUX
fnp-4682	182	22	highlighted	highlight	VERB
fnp-4682	182	23	by	by	ADP
fnp-4682	182	24	arrowheads	arrowhead	NOUN
fnp-4682	182	25	.	.	PUNCT
fnp-4682	183	1	(	(	PUNCT
fnp-4682	183	2	b	b	X
fnp-4682	183	3	)	)	PUNCT
fnp-4682	183	4	the	the	DET
fnp-4682	183	5	multilayered	multilayered	ADJ
fnp-4682	183	6	appearance	appearance	NOUN
fnp-4682	183	7	of	of	ADP
fnp-4682	183	8	target	target	NOUN
fnp-4682	183	9	formations	formation	NOUN
fnp-4682	183	10	(	(	PUNCT
fnp-4682	183	11	arrowheads	arrowhead	NOUN
fnp-4682	183	12	)	)	PUNCT
fnp-4682	183	13	,	,	PUNCT
fnp-4682	183	14	with	with	ADP
fnp-4682	183	15	the	the	DET
fnp-4682	183	16	central	central	ADJ
fnp-4682	183	17	pale	pale	ADJ
fnp-4682	183	18	zone	zone	NOUN
fnp-4682	183	19	,	,	PUNCT
fnp-4682	183	20	dark	dark	ADJ
fnp-4682	183	21	mitochondria	mitochondria	NOUN
fnp-4682	183	22	-	-	PUNCT
fnp-4682	183	23	rich	rich	ADJ
fnp-4682	183	24	outer	outer	ADJ
fnp-4682	183	25	rim	rim	NOUN
fnp-4682	183	26	,	,	PUNCT
fnp-4682	183	27	and	and	CCONJ
fnp-4682	183	28	an	an	DET
fnp-4682	183	29	intermediate	intermediate	ADJ
fnp-4682	183	30	zone	zone	NOUN
fnp-4682	183	31	in	in	ADP
fnp-4682	183	32	between	between	ADP
fnp-4682	183	33	,	,	PUNCT
fnp-4682	183	34	is	be	AUX
fnp-4682	183	35	more	more	ADV
fnp-4682	183	36	obvious	obvious	ADJ
fnp-4682	183	37	on	on	ADP
fnp-4682	183	38	sdh	sdh	PROPN
fnp-4682	183	39	histochemistry	histochemistry	NOUN
fnp-4682	183	40	.	.	PUNCT
fnp-4682	184	1	(	(	PUNCT
fnp-4682	184	2	c	c	X
fnp-4682	184	3	)	)	PUNCT
fnp-4682	184	4	desmin	desmin	ADJ
fnp-4682	184	5	immunohistochemistry	immunohistochemistry	NOUN
fnp-4682	184	6	highlights	highlight	NOUN
fnp-4682	184	7	the	the	DET
fnp-4682	184	8	inner	inner	ADJ
fnp-4682	184	9	and	and	CCONJ
fnp-4682	184	10	intermediate	intermediate	ADJ
fnp-4682	184	11	zones	zone	NOUN
fnp-4682	184	12	of	of	ADP
fnp-4682	184	13	target	target	NOUN
fnp-4682	184	14	formations	formation	NOUN
fnp-4682	184	15	,	,	PUNCT
fnp-4682	184	16	where	where	SCONJ
fnp-4682	184	17	new	new	ADJ
fnp-4682	184	18	myofibrils	myofibril	NOUN
fnp-4682	184	19	are	be	AUX
fnp-4682	184	20	assembled	assemble	VERB
fnp-4682	184	21	;	;	PUNCT
fnp-4682	184	22	in	in	ADP
fnp-4682	184	23	some	some	DET
fnp-4682	184	24	cases	case	NOUN
fnp-4682	184	25	,	,	PUNCT
fnp-4682	184	26	desmin	desmin	ADJ
fnp-4682	184	27	staining	stain	VERB
fnp-4682	184	28	is	be	AUX
fnp-4682	184	29	most	most	ADV
fnp-4682	184	30	prominent	prominent	ADJ
fnp-4682	184	31	in	in	ADP
fnp-4682	184	32	the	the	DET
fnp-4682	184	33	intermediate	intermediate	ADJ
fnp-4682	184	34	zone	zone	NOUN
fnp-4682	184	35	(	(	PUNCT
fnp-4682	184	36	main	main	ADJ
fnp-4682	184	37	panel	panel	NOUN
fnp-4682	184	38	)	)	PUNCT
fnp-4682	184	39	,	,	PUNCT
fnp-4682	184	40	while	while	SCONJ
fnp-4682	184	41	in	in	ADP
fnp-4682	184	42	others	other	NOUN
fnp-4682	184	43	it	it	PRON
fnp-4682	184	44	is	be	AUX
fnp-4682	184	45	equally	equally	ADV
fnp-4682	184	46	prominent	prominent	ADJ
fnp-4682	184	47	in	in	ADP
fnp-4682	184	48	both	both	DET
fnp-4682	184	49	zones	zone	NOUN
fnp-4682	184	50	(	(	PUNCT
fnp-4682	184	51	inset	inset	NOUN
fnp-4682	184	52	)	)	PUNCT
fnp-4682	184	53	.	.	PUNCT
fnp-4682	185	1	(	(	PUNCT
fnp-4682	185	2	orange	orange	ADJ
fnp-4682	185	3	line	line	NOUN
fnp-4682	185	4	,	,	PUNCT
fnp-4682	185	5	inner	inner	ADJ
fnp-4682	185	6	zone	zone	NOUN
fnp-4682	185	7	boundary	boundary	NOUN
fnp-4682	185	8	;	;	PUNCT
fnp-4682	185	9	green	green	ADJ
fnp-4682	185	10	line	line	NOUN
fnp-4682	185	11	,	,	PUNCT
fnp-4682	185	12	intermediate	intermediate	ADJ
fnp-4682	185	13	zone	zone	NOUN
fnp-4682	185	14	boundary	boundary	NOUN
fnp-4682	185	15	;	;	PUNCT
fnp-4682	185	16	black	black	ADJ
fnp-4682	185	17	line	line	NOUN
fnp-4682	185	18	,	,	PUNCT
fnp-4682	185	19	outer	outer	ADJ
fnp-4682	185	20	zone	zone	NOUN
fnp-4682	185	21	boundary	boundary	NOUN
fnp-4682	185	22	.	.	PUNCT
fnp-4682	185	23	)	)	PUNCT
fnp-4682	186	1	(	(	PUNCT
fnp-4682	186	2	d	d	NOUN
fnp-4682	186	3	)	)	PUNCT
fnp-4682	186	4	.	.	PUNCT
fnp-4682	187	1	lc3	lc3	NOUN
fnp-4682	187	2	immunohistochemistry	immunohistochemistry	NOUN
fnp-4682	187	3	highlights	highlight	NOUN
fnp-4682	187	4	autophagosomes	autophagosome	NOUN
fnp-4682	187	5	,	,	PUNCT
fnp-4682	187	6	a	a	DET
fnp-4682	187	7	key	key	ADJ
fnp-4682	187	8	component	component	NOUN
fnp-4682	187	9	of	of	ADP
fnp-4682	187	10	the	the	DET
fnp-4682	187	11	quality	quality	NOUN
fnp-4682	187	12	-	-	PUNCT
fnp-4682	187	13	control	control	NOUN
fnp-4682	187	14	machinery	machinery	NOUN
fnp-4682	187	15	responsible	responsible	ADJ
fnp-4682	187	16	for	for	ADP
fnp-4682	187	17	degradation	degradation	NOUN
fnp-4682	187	18	of	of	ADP
fnp-4682	187	19	misassembled	misassemble	VERB
fnp-4682	187	20	or	or	CCONJ
fnp-4682	187	21	damaged	damaged	ADJ
fnp-4682	187	22	myofibrils	myofibril	NOUN
fnp-4682	187	23	;	;	PUNCT
fnp-4682	187	24	in	in	ADP
fnp-4682	187	25	some	some	DET
fnp-4682	187	26	target	target	NOUN
fnp-4682	187	27	formations	formation	NOUN
fnp-4682	187	28	,	,	PUNCT
fnp-4682	187	29	lc3	lc3	CCONJ
fnp-4682	187	30	staining	stain	VERB
fnp-4682	187	31	is	be	AUX
fnp-4682	187	32	most	most	ADV
fnp-4682	187	33	prominent	prominent	ADJ
fnp-4682	187	34	in	in	ADP
fnp-4682	187	35	the	the	DET
fnp-4682	187	36	central	central	ADJ
fnp-4682	187	37	zone	zone	NOUN
fnp-4682	187	38	(	(	PUNCT
fnp-4682	187	39	main	main	ADJ
fnp-4682	187	40	panel	panel	NOUN
fnp-4682	187	41	)	)	PUNCT
fnp-4682	187	42	,	,	PUNCT
fnp-4682	187	43	while	while	SCONJ
fnp-4682	187	44	in	in	ADP
fnp-4682	187	45	others	other	NOUN
fnp-4682	187	46	it	it	PRON
fnp-4682	187	47	is	be	AUX
fnp-4682	187	48	most	most	ADV
fnp-4682	187	49	prominent	prominent	ADJ
fnp-4682	187	50	in	in	ADP
fnp-4682	187	51	the	the	DET
fnp-4682	187	52	intermediate	intermediate	ADJ
fnp-4682	187	53	zone	zone	NOUN
fnp-4682	187	54	(	(	PUNCT
fnp-4682	187	55	inset	inset	NOUN
fnp-4682	187	56	)	)	PUNCT
fnp-4682	187	57	.	.	PUNCT
fnp-4682	188	1	different	different	ADJ
fnp-4682	188	2	patterns	pattern	NOUN
fnp-4682	188	3	of	of	ADP
fnp-4682	188	4	target	target	NOUN
fnp-4682	188	5	formation	formation	NOUN
fnp-4682	188	6	staining	stain	VERB
fnp-4682	188	7	observed	observe	VERB
fnp-4682	188	8	with	with	ADP
fnp-4682	188	9	desmin	desmin	ADJ
fnp-4682	188	10	and	and	CCONJ
fnp-4682	188	11	lc3	lc3	NOUN
fnp-4682	188	12	immunostains	immunostain	NOUN
fnp-4682	188	13	could	could	AUX
fnp-4682	188	14	reflect	reflect	VERB
fnp-4682	188	15	different	different	ADJ
fnp-4682	188	16	stages	stage	NOUN
fnp-4682	188	17	in	in	ADP
fnp-4682	188	18	myofibril	myofibril	NOUN
fnp-4682	188	19	assembly	assembly	NOUN
fnp-4682	188	20	following	follow	VERB
fnp-4682	188	21	fiber	fiber	NOUN
fnp-4682	188	22	reinnervation	reinnervation	NOUN
fnp-4682	188	23	.	.	PUNCT
fnp-4682	189	1	scale	scale	NOUN
fnp-4682	189	2	bar	bar	NOUN
fnp-4682	189	3	,	,	PUNCT
fnp-4682	189	4	50	50	NUM
fnp-4682	189	5	µm	µm	NOUN
fnp-4682	189	6	.	.	PUNCT
fnp-4682	189	7	to	to	PART
fnp-4682	189	8	investigate	investigate	VERB
fnp-4682	189	9	the	the	DET
fnp-4682	189	10	molecular	molecular	ADJ
fnp-4682	189	11	composition	composition	NOUN
fnp-4682	189	12	of	of	ADP
fnp-4682	189	13	targets	target	NOUN
fnp-4682	189	14	,	,	PUNCT
fnp-4682	189	15	krause	krause	NOUN
fnp-4682	189	16	and	and	CCONJ
fnp-4682	189	17	co	co	NOUN
fnp-4682	189	18	-	-	NOUN
fnp-4682	189	19	authors	author	NOUN
fnp-4682	189	20	employed	employ	VERB
fnp-4682	189	21	a	a	DET
fnp-4682	189	22	non	non	ADJ
fnp-4682	189	23	-	-	ADJ
fnp-4682	189	24	biased	biased	ADJ
fnp-4682	189	25	,	,	PUNCT
fnp-4682	189	26	hypothesis	hypothesis	NOUN
fnp-4682	189	27	-	-	PUNCT
fnp-4682	189	28	free	free	ADJ
fnp-4682	189	29	proteomic	proteomic	ADJ
fnp-4682	189	30	strategy	strategy	NOUN
fnp-4682	189	31	:	:	PUNCT
fnp-4682	189	32	they	they	PRON
fnp-4682	189	33	used	use	VERB
fnp-4682	189	34	20	20	NUM
fnp-4682	189	35	muscle	muscle	NOUN
fnp-4682	189	36	biopsies	biopsy	NOUN
fnp-4682	189	37	from	from	ADP
fnp-4682	189	38	patients	patient	NOUN
fnp-4682	189	39	with	with	ADP
fnp-4682	189	40	neurogenic	neurogenic	ADJ
fnp-4682	189	41	muscle	muscle	NOUN
fnp-4682	189	42	atrophy	atrophy	NOUN
fnp-4682	189	43	to	to	ADP
fnp-4682	189	44	micro	micro	ADJ
fnp-4682	189	45	-	-	NOUN
fnp-4682	189	46	dissect	dissect	VERB
fnp-4682	189	47	targets	target	NOUN
fnp-4682	189	48	and	and	CCONJ
fnp-4682	189	49	analogously	analogously	ADV
fnp-4682	189	50	sized	sized	ADJ
fnp-4682	189	51	portions	portion	NOUN
fnp-4682	189	52	of	of	ADP
fnp-4682	189	53	uninvolved	uninvolved	ADJ
fnp-4682	189	54	type	type	NOUN
fnp-4682	189	55	1	1	NUM
fnp-4682	189	56	fibers	fiber	NOUN
fnp-4682	189	57	,	,	PUNCT
fnp-4682	189	58	and	and	CCONJ
fnp-4682	189	59	then	then	ADV
fnp-4682	189	60	compared	compare	VERB
fnp-4682	189	61	the	the	DET
fnp-4682	189	62	protein	protein	NOUN
fnp-4682	189	63	composition	composition	NOUN
fnp-4682	189	64	of	of	ADP
fnp-4682	189	65	both	both	DET
fnp-4682	189	66	samples	sample	NOUN
fnp-4682	189	67	via	via	ADP
fnp-4682	189	68	label	label	NOUN
fnp-4682	189	69	-	-	PUNCT
fnp-4682	189	70	free	free	ADJ
fnp-4682	189	71	mass	mass	NOUN
fnp-4682	189	72	spectroscopy	spectroscopy	NOUN
fnp-4682	189	73	.	.	PUNCT
fnp-4682	190	1	out	out	ADP
fnp-4682	190	2	of	of	ADP
fnp-4682	190	3	1026	1026	NUM
fnp-4682	190	4	proteins	protein	NOUN
fnp-4682	190	5	identified	identify	VERB
fnp-4682	190	6	in	in	ADP
fnp-4682	190	7	these	these	DET
fnp-4682	190	8	samples	sample	NOUN
fnp-4682	190	9	,	,	PUNCT
fnp-4682	190	10	55	55	NUM
fnp-4682	190	11	proteins	protein	NOUN
fnp-4682	190	12	were	be	AUX
fnp-4682	190	13	overrepresented	overrepresente	VERB
fnp-4682	190	14	and	and	CCONJ
fnp-4682	190	15	40	40	NUM
fnp-4682	190	16	proteins	protein	NOUN
fnp-4682	190	17	underrepresented	underrepresente	VERB
fnp-4682	190	18	in	in	ADP
fnp-4682	190	19	targets	target	NOUN
fnp-4682	190	20	compared	compare	VERB
fnp-4682	190	21	to	to	ADP
fnp-4682	190	22	the	the	DET
fnp-4682	190	23	control	control	NOUN
fnp-4682	190	24	regions	region	NOUN
fnp-4682	190	25	of	of	ADP
fnp-4682	190	26	type	type	NOUN
fnp-4682	190	27	1	1	NUM
fnp-4682	190	28	fibers	fiber	NOUN
fnp-4682	190	29	.	.	PUNCT
fnp-4682	191	1	unsurprisingly	unsurprisingly	ADV
fnp-4682	191	2	,	,	PUNCT
fnp-4682	191	3	the	the	DET
fnp-4682	191	4	underrepresented	underrepresented	ADJ
fnp-4682	191	5	proteins	protein	NOUN
fnp-4682	191	6	were	be	AUX
fnp-4682	191	7	mainly	mainly	ADV
fnp-4682	191	8	mitochondrial	mitochondrial	ADJ
fnp-4682	191	9	proteins	protein	NOUN
fnp-4682	191	10	.	.	PUNCT
fnp-4682	192	1	the	the	DET
fnp-4682	192	2	overrepresented	overrepresente	VERB
fnp-4682	192	3	proteins	protein	NOUN
fnp-4682	192	4	were	be	AUX
fnp-4682	192	5	more	more	ADV
fnp-4682	192	6	interesting	interesting	ADJ
fnp-4682	192	7	and	and	CCONJ
fnp-4682	192	8	could	could	AUX
fnp-4682	192	9	be	be	AUX
fnp-4682	192	10	classified	classify	VERB
fnp-4682	192	11	into	into	ADP
fnp-4682	192	12	four	four	NUM
fnp-4682	192	13	main	main	ADJ
fnp-4682	192	14	groups	group	NOUN
fnp-4682	192	15	based	base	VERB
fnp-4682	192	16	on	on	ADP
fnp-4682	192	17	their	their	PRON
fnp-4682	192	18	subcellular	subcellular	ADJ
fnp-4682	192	19	localization	localization	NOUN
fnp-4682	192	20	and/or	and/or	CCONJ
fnp-4682	192	21	function	function	NOUN
fnp-4682	192	22	:	:	PUNCT
fnp-4682	192	23	(	(	PUNCT
fnp-4682	192	24	i	i	NOUN
fnp-4682	192	25	)	)	PUNCT
fnp-4682	192	26	z	z	NOUN
fnp-4682	192	27	-	-	PUNCT
fnp-4682	192	28	disc	disc	NOUN
fnp-4682	192	29	and	and	CCONJ
fnp-4682	192	30	actin	actin	NOUN
fnp-4682	192	31	dynamics	dynamic	NOUN
fnp-4682	192	32	(	(	PUNCT
fnp-4682	192	33	15	15	NUM
fnp-4682	192	34	proteins	protein	NOUN
fnp-4682	192	35	,	,	PUNCT
fnp-4682	192	36	including	include	VERB
fnp-4682	192	37	filamin	filamin	PROPN
fnp-4682	192	38	c	c	PROPN
fnp-4682	192	39	and	and	CCONJ
fnp-4682	192	40	desmin	desmin	ADJ
fnp-4682	192	41	)	)	PUNCT
fnp-4682	192	42	,	,	PUNCT
fnp-4682	192	43	(	(	PUNCT
fnp-4682	192	44	ii	ii	NOUN
fnp-4682	192	45	)	)	PUNCT
fnp-4682	192	46	myosins	myosin	NOUN
fnp-4682	192	47	and	and	CCONJ
fnp-4682	192	48	myosin	myosin	NOUN
fnp-4682	192	49	-	-	PUNCT
fnp-4682	192	50	associated	associate	VERB
fnp-4682	192	51	proteins	protein	NOUN
fnp-4682	192	52	(	(	PUNCT
fnp-4682	192	53	10	10	NUM
fnp-4682	192	54	)	)	PUNCT
fnp-4682	192	55	,	,	PUNCT
fnp-4682	192	56	(	(	PUNCT
fnp-4682	192	57	iii	iii	X
fnp-4682	192	58	)	)	PUNCT
fnp-4682	192	59	protein	protein	NOUN
fnp-4682	192	60	biosynthesis	biosynthesis	NOUN
fnp-4682	192	61	(	(	PUNCT
fnp-4682	192	62	10	10	NUM
fnp-4682	192	63	,	,	PUNCT
fnp-4682	192	64	including	include	VERB
fnp-4682	192	65	ribosomal	ribosomal	NOUN
fnp-4682	192	66	proteins	protein	NOUN
fnp-4682	192	67	)	)	PUNCT
fnp-4682	192	68	,	,	PUNCT
fnp-4682	192	69	and	and	CCONJ
fnp-4682	192	70	(	(	PUNCT
fnp-4682	192	71	iv	iv	X
fnp-4682	192	72	)	)	PUNCT
fnp-4682	192	73	molecular	molecular	ADJ
fnp-4682	192	74	chaperones	chaperone	NOUN
fnp-4682	192	75	(	(	PUNCT
fnp-4682	192	76	5	5	NUM
fnp-4682	192	77	,	,	PUNCT
fnp-4682	192	78	including	include	VERB
fnp-4682	192	79	alpha(b)-crystallin	alpha(b)-crystallin	PROPN
fnp-4682	192	80	and	and	CCONJ
fnp-4682	192	81	bag3	bag3	PROPN
fnp-4682	192	82	)	)	PUNCT
fnp-4682	192	83	;	;	PUNCT
fnp-4682	192	84	the	the	DET
fnp-4682	192	85	remaining	remain	VERB
fnp-4682	192	86	15	15	NUM
fnp-4682	192	87	proteins	protein	NOUN
fnp-4682	192	88	were	be	AUX
fnp-4682	192	89	classified	classify	VERB
fnp-4682	192	90	as	as	ADP
fnp-4682	192	91	“	"	PUNCT
fnp-4682	192	92	other	other	ADJ
fnp-4682	192	93	.	.	PUNCT
fnp-4682	192	94	”	"	PUNCT
fnp-4682	193	1	the	the	DET
fnp-4682	193	2	key	key	ADJ
fnp-4682	193	3	mass	mass	NOUN
fnp-4682	193	4	spectroscopy	spectroscopy	NOUN
fnp-4682	193	5	findings	finding	NOUN
fnp-4682	193	6	were	be	AUX
fnp-4682	193	7	then	then	ADV
fnp-4682	193	8	validated	validate	VERB
fnp-4682	193	9	by	by	ADP
fnp-4682	193	10	immunofluorescent	immunofluorescent	VERB
fnp-4682	193	11	staining	stain	VERB
fnp-4682	193	12	and	and	CCONJ
fnp-4682	193	13	showed	show	VERB
fnp-4682	193	14	zonal	zonal	ADJ
fnp-4682	193	15	pattern	pattern	NOUN
fnp-4682	193	16	of	of	ADP
fnp-4682	193	17	expression	expression	NOUN
fnp-4682	193	18	,	,	PUNCT
fnp-4682	193	19	with	with	ADP
fnp-4682	193	20	filamin	filamin	NOUN
fnp-4682	193	21	c	c	NOUN
fnp-4682	193	22	,	,	PUNCT
fnp-4682	193	23	other	other	ADJ
fnp-4682	193	24	z	z	NOUN
fnp-4682	193	25	-	-	PUNCT
fnp-4682	193	26	disc	disc	NOUN
fnp-4682	193	27	proteins	protein	NOUN
fnp-4682	193	28	,	,	PUNCT
fnp-4682	193	29	and	and	CCONJ
fnp-4682	193	30	chaperones	chaperone	NOUN
fnp-4682	193	31	in	in	ADP
fnp-4682	193	32	the	the	DET
fnp-4682	193	33	central	central	ADJ
fnp-4682	193	34	zone	zone	NOUN
fnp-4682	193	35	,	,	PUNCT
fnp-4682	193	36	desmin	desmin	ADJ
fnp-4682	193	37	mainly	mainly	ADV
fnp-4682	193	38	in	in	ADP
fnp-4682	193	39	the	the	DET
fnp-4682	193	40	intermediate	intermediate	ADJ
fnp-4682	193	41	zone	zone	NOUN
fnp-4682	193	42	(	(	PUNCT
fnp-4682	193	43	fig	fig	NOUN
fnp-4682	193	44	.	.	PUNCT
fnp-4682	193	45	5c	5c	NUM
fnp-4682	193	46	)	)	PUNCT
fnp-4682	193	47	,	,	PUNCT
fnp-4682	193	48	and	and	CCONJ
fnp-4682	193	49	myosins	myosin	NOUN
fnp-4682	193	50	in	in	ADP
fnp-4682	193	51	both	both	DET
fnp-4682	193	52	zones	zone	NOUN
fnp-4682	193	53	.	.	PUNCT
fnp-4682	194	1	the	the	DET
fnp-4682	194	2	model	model	NOUN
fnp-4682	194	3	that	that	PRON
fnp-4682	194	4	emerged	emerge	VERB
fnp-4682	194	5	from	from	ADP
fnp-4682	194	6	these	these	DET
fnp-4682	194	7	proteomic	proteomic	ADJ
fnp-4682	194	8	findings	finding	NOUN
fnp-4682	194	9	suggests	suggest	VERB
fnp-4682	194	10	that	that	SCONJ
fnp-4682	194	11	the	the	DET
fnp-4682	194	12	central	central	ADJ
fnp-4682	194	13	and	and	CCONJ
fnp-4682	194	14	intermediate	intermediate	ADJ
fnp-4682	194	15	zones	zone	NOUN
fnp-4682	194	16	are	be	AUX
fnp-4682	194	17	the	the	DET
fnp-4682	194	18	sites	site	NOUN
fnp-4682	194	19	of	of	ADP
fnp-4682	194	20	new	new	ADJ
fnp-4682	194	21	myofibril	myofibril	NOUN
fnp-4682	194	22	synthesis	synthesis	NOUN
fnp-4682	194	23	;	;	PUNCT
fnp-4682	194	24	premyofibrils	premyofibril	NOUN
fnp-4682	194	25	are	be	AUX
fnp-4682	194	26	formed	form	VERB
fnp-4682	194	27	in	in	ADP
fnp-4682	194	28	the	the	DET
fnp-4682	194	29	central	central	ADJ
fnp-4682	194	30	zone	zone	NOUN
fnp-4682	194	31	,	,	PUNCT
fnp-4682	194	32	and	and	CCONJ
fnp-4682	194	33	then	then	ADV
fnp-4682	194	34	assembled	assemble	VERB
fnp-4682	194	35	and	and	CCONJ
fnp-4682	194	36	linked	link	VERB
fnp-4682	194	37	with	with	ADP
fnp-4682	194	38	the	the	DET
fnp-4682	194	39	existing	exist	VERB
fnp-4682	194	40	myofibrils	myofibril	NOUN
fnp-4682	194	41	in	in	ADP
fnp-4682	194	42	the	the	DET
fnp-4682	194	43	intermediate	intermediate	ADJ
fnp-4682	194	44	zone	zone	NOUN
fnp-4682	194	45	.	.	PUNCT
fnp-4682	195	1	chaperones	chaperone	NOUN
fnp-4682	195	2	and	and	CCONJ
fnp-4682	195	3	other	other	ADJ
fnp-4682	195	4	components	component	NOUN
fnp-4682	195	5	of	of	ADP
fnp-4682	195	6	the	the	DET
fnp-4682	195	7	machinery	machinery	NOUN
fnp-4682	195	8	involved	involve	VERB
fnp-4682	195	9	in	in	ADP
fnp-4682	195	10	chaperone	chaperone	NOUN
fnp-4682	195	11	-	-	PUNCT
fnp-4682	195	12	assisted	assist	VERB
fnp-4682	195	13	selective	selective	ADJ
fnp-4682	195	14	autophagy	autophagy	NOUN
fnp-4682	195	15	(	(	PUNCT
fnp-4682	195	16	such	such	ADJ
fnp-4682	195	17	as	as	ADP
fnp-4682	195	18	autophagosomal	autophagosomal	ADJ
fnp-4682	195	19	protein	protein	NOUN
fnp-4682	195	20	lc3	lc3	NOUN
fnp-4682	195	21	;	;	PUNCT
fnp-4682	195	22	fig	fig	NOUN
fnp-4682	195	23	.	.	PUNCT
fnp-4682	196	1	5d	5d	NUM
fnp-4682	196	2	)	)	PUNCT
fnp-4682	196	3	are	be	AUX
fnp-4682	196	4	enriched	enrich	VERB
fnp-4682	196	5	in	in	ADP
fnp-4682	196	6	both	both	DET
fnp-4682	196	7	zones	zone	NOUN
fnp-4682	196	8	,	,	PUNCT
fnp-4682	196	9	providing	provide	VERB
fnp-4682	196	10	a	a	DET
fnp-4682	196	11	quality	quality	NOUN
fnp-4682	196	12	-	-	PUNCT
fnp-4682	196	13	control	control	NOUN
fnp-4682	196	14	mechanism	mechanism	NOUN
fnp-4682	196	15	that	that	PRON
fnp-4682	196	16	ensures	ensure	VERB
fnp-4682	196	17	that	that	SCONJ
fnp-4682	196	18	nascent	nascent	ADJ
fnp-4682	196	19	myofibrils	myofibril	NOUN
fnp-4682	196	20	are	be	AUX
fnp-4682	196	21	either	either	ADV
fnp-4682	196	22	properly	properly	ADV
fnp-4682	196	23	built	build	VERB
fnp-4682	196	24	and	and	CCONJ
fnp-4682	196	25	assembled	assemble	VERB
fnp-4682	196	26	or	or	CCONJ
fnp-4682	196	27	immediately	immediately	ADV
fnp-4682	196	28	degraded	degrade	VERB
fnp-4682	196	29	.	.	PUNCT
fnp-4682	197	1	while	while	SCONJ
fnp-4682	197	2	this	this	DET
fnp-4682	197	3	study	study	NOUN
fnp-4682	197	4	represents	represent	VERB
fnp-4682	197	5	a	a	DET
fnp-4682	197	6	major	major	ADJ
fnp-4682	197	7	advance	advance	NOUN
fnp-4682	197	8	in	in	ADP
fnp-4682	197	9	our	our	PRON
fnp-4682	197	10	understanding	understanding	NOUN
fnp-4682	197	11	of	of	ADP
fnp-4682	197	12	the	the	DET
fnp-4682	197	13	reinnervation	reinnervation	NOUN
fnp-4682	197	14	-	-	PUNCT
fnp-4682	197	15	induced	induce	VERB
fnp-4682	197	16	myofiber	myofiber	ADJ
fnp-4682	197	17	rebuilding	rebuild	VERB
fnp-4682	197	18	mechanisms	mechanism	NOUN
fnp-4682	197	19	,	,	PUNCT
fnp-4682	197	20	some	some	DET
fnp-4682	197	21	aspects	aspect	NOUN
fnp-4682	197	22	of	of	ADP
fnp-4682	197	23	this	this	DET
fnp-4682	197	24	process	process	NOUN
fnp-4682	197	25	still	still	ADV
fnp-4682	197	26	remain	remain	VERB
fnp-4682	197	27	to	to	PART
fnp-4682	197	28	be	be	AUX
fnp-4682	197	29	elucidated	elucidate	VERB
fnp-4682	197	30	.	.	PUNCT
fnp-4682	198	1	for	for	ADP
fnp-4682	198	2	example	example	NOUN
fnp-4682	198	3	,	,	PUNCT
fnp-4682	198	4	it	it	PRON
fnp-4682	198	5	is	be	AUX
fnp-4682	198	6	not	not	PART
fnp-4682	198	7	clear	clear	ADJ
fnp-4682	198	8	why	why	SCONJ
fnp-4682	198	9	targets	target	NOUN
fnp-4682	198	10	are	be	AUX
fnp-4682	198	11	mainly	mainly	ADV
fnp-4682	198	12	seen	see	VERB
fnp-4682	198	13	in	in	ADP
fnp-4682	198	14	type	type	NOUN
fnp-4682	198	15	1	1	NUM
fnp-4682	198	16	fibers	fiber	NOUN
fnp-4682	198	17	.	.	PUNCT
fnp-4682	199	1	does	do	AUX
fnp-4682	199	2	the	the	DET
fnp-4682	199	3	same	same	ADJ
fnp-4682	199	4	process	process	NOUN
fnp-4682	199	5	occur	occur	VERB
fnp-4682	199	6	in	in	ADP
fnp-4682	199	7	a	a	DET
fnp-4682	199	8	less	less	ADV
fnp-4682	199	9	structured	structured	ADJ
fnp-4682	199	10	/	/	PUNCT
fnp-4682	199	11	morphologically	morphologically	ADV
fnp-4682	199	12	less	less	ADV
fnp-4682	199	13	distinctive	distinctive	ADJ
fnp-4682	199	14	way	way	NOUN
fnp-4682	199	15	in	in	ADP
fnp-4682	199	16	type	type	NOUN
fnp-4682	199	17	2	2	NUM
fnp-4682	199	18	fibers	fiber	NOUN
fnp-4682	199	19	,	,	PUNCT
fnp-4682	199	20	or	or	CCONJ
fnp-4682	199	21	are	be	AUX
fnp-4682	199	22	reinnervated	reinnervate	VERB
fnp-4682	199	23	type	type	NOUN
fnp-4682	199	24	2	2	NUM
fnp-4682	199	25	fibers	fiber	NOUN
fnp-4682	199	26	rebuilt	rebuild	VERB
fnp-4682	199	27	through	through	ADP
fnp-4682	199	28	entirely	entirely	ADV
fnp-4682	199	29	different	different	ADJ
fnp-4682	199	30	molecular	molecular	ADJ
fnp-4682	199	31	mechanisms	mechanism	NOUN
fnp-4682	199	32	?	?	PUNCT
fnp-4682	200	1	furthermore	furthermore	ADV
fnp-4682	200	2	,	,	PUNCT
fnp-4682	200	3	it	it	PRON
fnp-4682	200	4	remains	remain	VERB
fnp-4682	200	5	to	to	PART
fnp-4682	200	6	be	be	AUX
fnp-4682	200	7	established	establish	VERB
fnp-4682	200	8	how	how	SCONJ
fnp-4682	200	9	the	the	DET
fnp-4682	200	10	motor	motor	NOUN
fnp-4682	200	11	neuron	neuron	PROPN
fnp-4682	200	12	axon	axon	NOUN
fnp-4682	200	13	and	and	CCONJ
fnp-4682	200	14	muscle	muscle	NOUN
fnp-4682	200	15	fiber	fiber	NOUN
fnp-4682	200	16	interact	interact	VERB
fnp-4682	200	17	to	to	PART
fnp-4682	200	18	orchestrate	orchestrate	VERB
fnp-4682	200	19	this	this	DET
fnp-4682	200	20	highly	highly	ADV
fnp-4682	200	21	organized	organize	VERB
fnp-4682	200	22	process	process	NOUN
fnp-4682	200	23	of	of	ADP
fnp-4682	200	24	new	new	ADJ
fnp-4682	200	25	myofibril	myofibril	NOUN
fnp-4682	200	26	formation	formation	NOUN
fnp-4682	200	27	.	.	PUNCT
fnp-4682	201	1	7	7	X
fnp-4682	201	2	.	.	X
fnp-4682	201	3	sporadic	sporadic	ADJ
fnp-4682	201	4	inclusion	inclusion	NOUN
fnp-4682	201	5	body	body	NOUN
fnp-4682	201	6	myositis	myositis	NOUN
fnp-4682	201	7	revisited	revisit	VERB
fnp-4682	201	8	:	:	PUNCT
fnp-4682	201	9	what	what	PRON
fnp-4682	201	10	comes	come	VERB
fnp-4682	201	11	first	first	ADV
fnp-4682	201	12	,	,	PUNCT
fnp-4682	201	13	inflammation	inflammation	NOUN
fnp-4682	201	14	or	or	CCONJ
fnp-4682	201	15	myodegeneration	myodegeneration	NOUN
fnp-4682	201	16	?	?	PUNCT
fnp-4682	202	1	sporadic	sporadic	ADJ
fnp-4682	202	2	inclusion	inclusion	NOUN
fnp-4682	202	3	body	body	NOUN
fnp-4682	202	4	myositis	myositis	PROPN
fnp-4682	202	5	(	(	PUNCT
fnp-4682	202	6	sibm	sibm	NOUN
fnp-4682	202	7	)	)	PUNCT
fnp-4682	202	8	primarily	primarily	ADV
fnp-4682	202	9	affects	affect	VERB
fnp-4682	202	10	people	people	NOUN
fnp-4682	202	11	older	old	ADJ
fnp-4682	202	12	than	than	ADP
fnp-4682	202	13	50	50	NUM
fnp-4682	202	14	and	and	CCONJ
fnp-4682	202	15	has	have	VERB
fnp-4682	202	16	distinctive	distinctive	ADJ
fnp-4682	202	17	clinicopathologic	clinicopathologic	ADJ
fnp-4682	202	18	features	feature	NOUN
fnp-4682	202	19	that	that	PRON
fnp-4682	202	20	differentiate	differentiate	VERB
fnp-4682	202	21	it	it	PRON
fnp-4682	202	22	from	from	ADP
fnp-4682	202	23	other	other	ADJ
fnp-4682	202	24	idiopathic	idiopathic	ADJ
fnp-4682	202	25	inflammatory	inflammatory	ADJ
fnp-4682	202	26	myopathies	myopathy	NOUN
fnp-4682	202	27	;	;	PUNCT
fnp-4682	202	28	clinically	clinically	ADV
fnp-4682	202	29	,	,	PUNCT
fnp-4682	202	30	there	there	PRON
fnp-4682	202	31	is	be	VERB
fnp-4682	202	32	predominant	predominant	ADJ
fnp-4682	202	33	involvement	involvement	NOUN
fnp-4682	202	34	of	of	ADP
fnp-4682	202	35	quadriceps	quadricep	NOUN
fnp-4682	202	36	and	and	CCONJ
fnp-4682	202	37	finger	finger	NOUN
fnp-4682	202	38	flexor	flexor	ADJ
fnp-4682	202	39	muscles	muscle	NOUN
fnp-4682	202	40	,	,	PUNCT
fnp-4682	202	41	while	while	SCONJ
fnp-4682	202	42	pathologically	pathologically	ADV
fnp-4682	202	43	,	,	PUNCT
fnp-4682	202	44	there	there	PRON
fnp-4682	202	45	is	be	VERB
fnp-4682	202	46	endomysial	endomysial	ADJ
fnp-4682	202	47	inflammation	inflammation	NOUN
fnp-4682	202	48	accompanied	accompany	VERB
fnp-4682	202	49	by	by	ADP
fnp-4682	202	50	diffuse	diffuse	PROPN
fnp-4682	202	51	mhc	mhc	PROPN
fnp-4682	202	52	-	-	PUNCT
fnp-4682	202	53	i	i	PRON
fnp-4682	202	54	upregulation	upregulation	NOUN
fnp-4682	202	55	and	and	CCONJ
fnp-4682	202	56	invasion	invasion	NOUN
fnp-4682	202	57	of	of	ADP
fnp-4682	202	58	intact	intact	ADJ
fnp-4682	202	59	muscle	muscle	NOUN
fnp-4682	202	60	fibers	fiber	NOUN
fnp-4682	202	61	by	by	ADP
fnp-4682	202	62	cytotoxic	cytotoxic	ADJ
fnp-4682	202	63	cd8	cd8	PROPN
fnp-4682	202	64	+	+	PROPN
fnp-4682	202	65	t	t	PROPN
fnp-4682	202	66	lymphocytes	lymphocyte	NOUN
fnp-4682	202	67	and	and	CCONJ
fnp-4682	202	68	macrophages	macrophage	NOUN
fnp-4682	202	69	,	,	PUNCT
fnp-4682	202	70	along	along	ADP
fnp-4682	202	71	with	with	ADP
fnp-4682	202	72	mitochondrial	mitochondrial	ADJ
fnp-4682	202	73	abnormalities	abnormality	NOUN
fnp-4682	202	74	,	,	PUNCT
fnp-4682	202	75	chronic	chronic	ADJ
fnp-4682	202	76	myopathic	myopathic	ADJ
fnp-4682	202	77	features	feature	NOUN
fnp-4682	202	78	resembling	resemble	VERB
fnp-4682	202	79	muscular	muscular	ADJ
fnp-4682	202	80	dystrophy	dystrophy	NOUN
fnp-4682	202	81	,	,	PUNCT
fnp-4682	202	82	rimmed	rimmed	ADJ
fnp-4682	202	83	vacuoles	vacuole	NOUN
fnp-4682	202	84	,	,	PUNCT
fnp-4682	202	85	and	and	CCONJ
fnp-4682	202	86	p62and	p62and	PROPN
fnp-4682	202	87	tdp-43	tdp-43	PROPN
fnp-4682	202	88	-	-	PUNCT
fnp-4682	202	89	positive	positive	ADJ
fnp-4682	202	90	protein	protein	NOUN
fnp-4682	202	91	aggregates	aggregate	NOUN
fnp-4682	202	92	.	.	PUNCT
fnp-4682	203	1	however	however	ADV
fnp-4682	203	2	,	,	PUNCT
fnp-4682	203	3	pathogenesis	pathogenesis	NOUN
fnp-4682	203	4	of	of	ADP
fnp-4682	203	5	sibm	sibm	NOUN
fnp-4682	203	6	remains	remains	AUX
fnp-4682	203	7	poorly	poorly	ADV
fnp-4682	203	8	understood	understand	VERB
fnp-4682	203	9	.	.	PUNCT
fnp-4682	204	1	in	in	ADP
fnp-4682	204	2	particular	particular	ADJ
fnp-4682	204	3	,	,	PUNCT
fnp-4682	204	4	the	the	DET
fnp-4682	204	5	role	role	NOUN
fnp-4682	204	6	of	of	ADP
fnp-4682	204	7	inflammation	inflammation	NOUN
fnp-4682	204	8	has	have	AUX
fnp-4682	204	9	remained	remain	VERB
fnp-4682	204	10	controversial	controversial	ADJ
fnp-4682	204	11	:	:	PUNCT
fnp-4682	204	12	although	although	SCONJ
fnp-4682	204	13	sibm	sibm	NOUN
fnp-4682	204	14	muscle	muscle	NOUN
fnp-4682	204	15	biopsies	biopsy	NOUN
fnp-4682	204	16	typically	typically	ADV
fnp-4682	204	17	show	show	VERB
fnp-4682	204	18	prominent	prominent	ADJ
fnp-4682	204	19	inflammatory	inflammatory	ADJ
fnp-4682	204	20	infiltrates	infiltrate	NOUN
fnp-4682	204	21	,	,	PUNCT
fnp-4682	204	22	the	the	DET
fnp-4682	204	23	disease	disease	NOUN
fnp-4682	204	24	does	do	AUX
fnp-4682	204	25	not	not	PART
fnp-4682	204	26	respond	respond	VERB
fnp-4682	204	27	to	to	ADP
fnp-4682	204	28	immunosuppression	immunosuppression	NOUN
fnp-4682	204	29	(	(	PUNCT
fnp-4682	204	30	or	or	CCONJ
fnp-4682	204	31	any	any	DET
fnp-4682	204	32	other	other	ADJ
fnp-4682	204	33	therapy	therapy	NOUN
fnp-4682	204	34	)	)	PUNCT
fnp-4682	204	35	and	and	CCONJ
fnp-4682	204	36	generally	generally	ADV
fnp-4682	204	37	leads	lead	VERB
fnp-4682	204	38	to	to	ADP
fnp-4682	204	39	wheelchair	wheelchair	NOUN
fnp-4682	204	40	dependence	dependence	NOUN
fnp-4682	204	41	~15	~15	X
fnp-4682	204	42	years	year	NOUN
fnp-4682	204	43	following	follow	VERB
fnp-4682	204	44	the	the	DET
fnp-4682	204	45	diagnosis	diagnosis	NOUN
fnp-4682	204	46	.	.	PUNCT
fnp-4682	205	1	several	several	ADJ
fnp-4682	205	2	important	important	ADJ
fnp-4682	205	3	studies	study	NOUN
fnp-4682	205	4	published	publish	VERB
fnp-4682	205	5	in	in	ADP
fnp-4682	205	6	2019	2019	NUM
fnp-4682	205	7	[	[	X
fnp-4682	205	8	and	and	CCONJ
fnp-4682	205	9	discussed	discuss	VERB
fnp-4682	205	10	in	in	ADP
fnp-4682	205	11	the	the	DET
fnp-4682	205	12	first	first	ADJ
fnp-4682	205	13	paper	paper	NOUN
fnp-4682	205	14	in	in	ADP
fnp-4682	205	15	this	this	DET
fnp-4682	205	16	review	review	NOUN
fnp-4682	205	17	series	series	NOUN
fnp-4682	205	18	(	(	PUNCT
fnp-4682	205	19	margeta	margeta	NOUN
fnp-4682	205	20	,	,	PUNCT
fnp-4682	205	21	2020	2020	NUM
fnp-4682	205	22	)	)	PUNCT
fnp-4682	205	23	]	]	PUNCT
fnp-4682	205	24	suggested	suggest	VERB
fnp-4682	205	25	that	that	SCONJ
fnp-4682	205	26	the	the	DET
fnp-4682	205	27	lack	lack	NOUN
fnp-4682	205	28	of	of	ADP
fnp-4682	205	29	response	response	NOUN
fnp-4682	205	30	to	to	ADP
fnp-4682	205	31	immunomodulatory	immunomodulatory	ADJ
fnp-4682	205	32	therapy	therapy	NOUN
fnp-4682	205	33	is	be	AUX
fnp-4682	205	34	due	due	ADJ
fnp-4682	205	35	to	to	ADP
fnp-4682	205	36	involvement	involvement	NOUN
fnp-4682	205	37	of	of	ADP
fnp-4682	205	38	terminally	terminally	ADV
fnp-4682	205	39	differentiated	differentiate	VERB
fnp-4682	205	40	effector	effector	NOUN
fnp-4682	205	41	memory	memory	NOUN
fnp-4682	205	42	t	t	PROPN
fnp-4682	205	43	cells	cell	NOUN
fnp-4682	205	44	(	(	PUNCT
fnp-4682	205	45	so	so	ADV
fnp-4682	205	46	-	-	PUNCT
fnp-4682	205	47	called	call	VERB
fnp-4682	205	48	temra	temra	NOUN
fnp-4682	205	49	cells	cell	NOUN
fnp-4682	205	50	)	)	PUNCT
fnp-4682	205	51	,	,	PUNCT
fnp-4682	205	52	which	which	PRON
fnp-4682	205	53	are	be	AUX
fnp-4682	205	54	positive	positive	ADJ
fnp-4682	205	55	for	for	ADP
fnp-4682	205	56	klrg1	klrg1	NOUN
fnp-4682	205	57	(	(	PUNCT
fnp-4682	205	58	killer	killer	NOUN
fnp-4682	205	59	cell	cell	NOUN
fnp-4682	205	60	lectin	lectin	NOUN
fnp-4682	205	61	-	-	PUNCT
fnp-4682	205	62	like	like	ADJ
fnp-4682	205	63	receptor	receptor	NOUN
fnp-4682	205	64	g1	g1	NOUN
fnp-4682	205	65	;	;	PUNCT
fnp-4682	205	66	a	a	DET
fnp-4682	205	67	marker	marker	NOUN
fnp-4682	205	68	of	of	ADP
fnp-4682	205	69	t	t	NOUN
fnp-4682	205	70	cell	cell	NOUN
fnp-4682	205	71	exhaustion	exhaustion	NOUN
fnp-4682	205	72	)	)	PUNCT
fnp-4682	205	73	and	and	CCONJ
fnp-4682	205	74	resistant	resistant	ADJ
fnp-4682	205	75	to	to	ADP
fnp-4682	205	76	steroid	steroid	NOUN
fnp-4682	205	77	-	-	PUNCT
fnp-4682	205	78	induced	induce	VERB
fnp-4682	205	79	apoptosis	apoptosis	NOUN
fnp-4682	205	80	(	(	PUNCT
fnp-4682	205	81	greenberg	greenberg	PROPN
fnp-4682	205	82	et	et	PROPN
fnp-4682	205	83	al	al	PROPN
fnp-4682	205	84	.	.	PROPN
fnp-4682	205	85	,	,	PUNCT
fnp-4682	205	86	2019	2019	NUM
fnp-4682	205	87	;	;	PUNCT
fnp-4682	205	88	knauss	knauss	PROPN
fnp-4682	205	89	et	et	PROPN
fnp-4682	205	90	al	al	PROPN
fnp-4682	205	91	.	.	PROPN
fnp-4682	205	92	,	,	PUNCT
fnp-4682	205	93	2019	2019	NUM
fnp-4682	205	94	)	)	PUNCT
fnp-4682	205	95	.	.	PUNCT
fnp-4682	206	1	several	several	ADJ
fnp-4682	206	2	important	important	ADJ
fnp-4682	206	3	follow	follow	NOUN
fnp-4682	206	4	-	-	PUNCT
fnp-4682	206	5	up	up	ADP
fnp-4682	206	6	studies	study	NOUN
fnp-4682	206	7	were	be	AUX
fnp-4682	206	8	published	publish	VERB
fnp-4682	206	9	in	in	ADP
fnp-4682	206	10	2022	2022	NUM
fnp-4682	206	11	,	,	PUNCT
fnp-4682	206	12	prompting	prompt	VERB
fnp-4682	206	13	me	i	PRON
fnp-4682	206	14	to	to	PART
fnp-4682	206	15	revisit	revisit	VERB
fnp-4682	206	16	this	this	DET
fnp-4682	206	17	important	important	ADJ
fnp-4682	206	18	topic	topic	NOUN
fnp-4682	206	19	in	in	ADP
fnp-4682	206	20	the	the	DET
fnp-4682	206	21	current	current	ADJ
fnp-4682	206	22	review	review	NOUN
fnp-4682	206	23	.	.	PUNCT
fnp-4682	207	1	our	our	PRON
fnp-4682	207	2	understanding	understanding	NOUN
fnp-4682	207	3	of	of	ADP
fnp-4682	207	4	sibm	sibm	NOUN
fnp-4682	207	5	pathogenesis	pathogenesis	NOUN
fnp-4682	207	6	has	have	AUX
fnp-4682	207	7	been	be	AUX
fnp-4682	207	8	limited	limit	VERB
fnp-4682	207	9	by	by	ADP
fnp-4682	207	10	the	the	DET
fnp-4682	207	11	lack	lack	NOUN
fnp-4682	207	12	of	of	ADP
fnp-4682	207	13	a	a	DET
fnp-4682	207	14	disease	disease	NOUN
fnp-4682	207	15	model	model	NOUN
fnp-4682	207	16	that	that	PRON
fnp-4682	207	17	replicates	replicate	VERB
fnp-4682	207	18	both	both	CCONJ
fnp-4682	207	19	inflammatory	inflammatory	ADJ
fnp-4682	207	20	and	and	CCONJ
fnp-4682	207	21	myodegenerative	myodegenerative	ADJ
fnp-4682	207	22	features	feature	NOUN
fnp-4682	207	23	of	of	ADP
fnp-4682	207	24	this	this	DET
fnp-4682	207	25	disease	disease	NOUN
fnp-4682	207	26	.	.	PUNCT
fnp-4682	208	1	to	to	PART
fnp-4682	208	2	circumvent	circumvent	VERB
fnp-4682	208	3	this	this	DET
fnp-4682	208	4	barrier	barrier	NOUN
fnp-4682	208	5	,	,	PUNCT
fnp-4682	208	6	britson	britson	NOUN
fnp-4682	208	7	and	and	CCONJ
fnp-4682	208	8	colleagues	colleague	NOUN
fnp-4682	208	9	developed	develop	VERB
fnp-4682	208	10	a	a	DET
fnp-4682	208	11	xenograft	xenograft	NOUN
fnp-4682	208	12	model	model	NOUN
fnp-4682	208	13	of	of	ADP
fnp-4682	208	14	sibm	sibm	NOUN
fnp-4682	208	15	,	,	PUNCT
fnp-4682	208	16	in	in	ADP
fnp-4682	208	17	which	which	PRON
fnp-4682	208	18	human	human	ADJ
fnp-4682	208	19	muscle	muscle	NOUN
fnp-4682	208	20	biopsy	biopsy	NOUN
fnp-4682	208	21	tissue	tissue	NOUN
fnp-4682	208	22	is	be	AUX
fnp-4682	208	23	transplanted	transplant	VERB
fnp-4682	208	24	into	into	ADP
fnp-4682	208	25	immunodeficient	immunodeficient	NOUN
fnp-4682	208	26	mice	mouse	NOUN
fnp-4682	208	27	;	;	PUNCT
fnp-4682	208	28	following	follow	VERB
fnp-4682	208	29	transplantation	transplantation	NOUN
fnp-4682	208	30	,	,	PUNCT
fnp-4682	208	31	transacted	transact	VERB
fnp-4682	208	32	mature	mature	ADJ
fnp-4682	208	33	muscle	muscle	NOUN
fnp-4682	208	34	fibers	fiber	NOUN
fnp-4682	208	35	degenerate	degenerate	ADJ
fnp-4682	208	36	and	and	CCONJ
fnp-4682	208	37	are	be	AUX
fnp-4682	208	38	replaced	replace	VERB
fnp-4682	208	39	by	by	ADP
fnp-4682	208	40	newly	newly	ADV
fnp-4682	208	41	formed	form	VERB
fnp-4682	208	42	fibers	fiber	NOUN
fnp-4682	208	43	generated	generate	VERB
fnp-4682	208	44	from	from	ADP
fnp-4682	208	45	satellite	satellite	NOUN
fnp-4682	208	46	cells	cell	NOUN
fnp-4682	208	47	that	that	PRON
fnp-4682	208	48	were	be	AUX
fnp-4682	208	49	harnessed	harness	VERB
fnp-4682	208	50	along	along	ADP
fnp-4682	208	51	with	with	ADP
fnp-4682	208	52	the	the	DET
fnp-4682	208	53	graft	graft	NOUN
fnp-4682	208	54	(	(	PUNCT
fnp-4682	208	55	britson	britson	PROPN
fnp-4682	208	56	et	et	PROPN
fnp-4682	208	57	al	al	PROPN
fnp-4682	208	58	.	.	PROPN
fnp-4682	208	59	,	,	PUNCT
fnp-4682	208	60	2022	2022	NUM
fnp-4682	208	61	)	)	PUNCT
fnp-4682	208	62	.	.	PUNCT
fnp-4682	209	1	remarkably	remarkably	ADV
fnp-4682	209	2	,	,	PUNCT
fnp-4682	209	3	in	in	ADP
fnp-4682	209	4	sibm	sibm	PROPN
fnp-4682	209	5	xenografts	xenografts	PROPN
fnp-4682	209	6	–	–	PUNCT
fnp-4682	209	7	but	but	CCONJ
fnp-4682	209	8	not	not	PART
fnp-4682	209	9	in	in	ADP
fnp-4682	209	10	the	the	DET
fnp-4682	209	11	xenografts	xenograft	NOUN
fnp-4682	209	12	generated	generate	VERB
fnp-4682	209	13	from	from	ADP
fnp-4682	209	14	relatively	relatively	ADV
fnp-4682	209	15	normal	normal	ADJ
fnp-4682	209	16	muscle	muscle	NOUN
fnp-4682	209	17	biopsies	biopsy	NOUN
fnp-4682	209	18	or	or	CCONJ
fnp-4682	209	19	from	from	ADP
fnp-4682	209	20	biopsies	biopsy	NOUN
fnp-4682	209	21	showing	show	VERB
fnp-4682	209	22	other	other	ADJ
fnp-4682	209	23	types	type	NOUN
fnp-4682	209	24	of	of	ADP
fnp-4682	209	25	myositis	myositis	NOUN
fnp-4682	209	26	–	–	PUNCT
fnp-4682	209	27	regenerated	regenerate	VERB
fnp-4682	209	28	myofibers	myofiber	NOUN
fnp-4682	209	29	showed	show	VERB
fnp-4682	209	30	typical	typical	ADJ
fnp-4682	209	31	features	feature	NOUN
fnp-4682	209	32	of	of	ADP
fnp-4682	209	33	sibm	sibm	NOUN
fnp-4682	209	34	,	,	PUNCT
fnp-4682	209	35	including	include	VERB
fnp-4682	209	36	mhc	mhc	PROPN
fnp-4682	209	37	-	-	PUNCT
fnp-4682	209	38	i	i	PROPN
fnp-4682	209	39	positivity	positivity	NOUN
fnp-4682	209	40	,	,	PUNCT
fnp-4682	209	41	rimmed	rimmed	ADJ
fnp-4682	209	42	vacuoles	vacuole	NOUN
fnp-4682	209	43	,	,	PUNCT
fnp-4682	209	44	loss	loss	NOUN
fnp-4682	209	45	of	of	ADP
fnp-4682	209	46	nuclear	nuclear	ADJ
fnp-4682	209	47	tdp-43	tdp-43	NOUN
fnp-4682	209	48	expression	expression	NOUN
fnp-4682	209	49	,	,	PUNCT
fnp-4682	209	50	and	and	CCONJ
fnp-4682	209	51	mitochondrial	mitochondrial	ADJ
fnp-4682	209	52	abnormalities	abnormality	NOUN
fnp-4682	209	53	(	(	PUNCT
fnp-4682	209	54	cox	cox	NOUN
fnp-4682	209	55	deficiency	deficiency	NOUN
fnp-4682	209	56	)	)	PUNCT
fnp-4682	209	57	.	.	PUNCT
fnp-4682	210	1	in	in	ADP
fnp-4682	210	2	addition	addition	NOUN
fnp-4682	210	3	,	,	PUNCT
fnp-4682	210	4	sibm	sibm	PROPN
fnp-4682	210	5	xenografts	xenograft	NOUN
fnp-4682	210	6	contained	contain	VERB
fnp-4682	210	7	donor	donor	NOUN
fnp-4682	210	8	-	-	PUNCT
fnp-4682	210	9	derived	derive	VERB
fnp-4682	210	10	oligoclonal	oligoclonal	NOUN
fnp-4682	210	11	cd8+klrg1	cd8+klrg1	PROPN
fnp-4682	210	12	+	+	CCONJ
fnp-4682	210	13	temra	temra	NOUN
fnp-4682	210	14	cells	cell	NOUN
fnp-4682	210	15	that	that	PRON
fnp-4682	210	16	were	be	AUX
fnp-4682	210	17	enriched	enrich	VERB
fnp-4682	210	18	compared	compare	VERB
fnp-4682	210	19	to	to	ADP
fnp-4682	210	20	the	the	DET
fnp-4682	210	21	source	source	NOUN
fnp-4682	210	22	sibm	sibm	NOUN
fnp-4682	210	23	biopsies	biopsy	NOUN
fnp-4682	210	24	.	.	PUNCT
fnp-4682	211	1	finally	finally	ADV
fnp-4682	211	2	,	,	PUNCT
fnp-4682	211	3	~50	~50	ADP
fnp-4682	211	4	%	%	NOUN
fnp-4682	211	5	of	of	ADP
fnp-4682	211	6	sibm	sibm	PROPN
fnp-4682	211	7	xenografts	xenografts	PROPN
fnp-4682	211	8	(	(	PUNCT
fnp-4682	211	9	but	but	CCONJ
fnp-4682	211	10	only	only	ADV
fnp-4682	211	11	3	3	NUM
fnp-4682	211	12	%	%	NOUN
fnp-4682	211	13	of	of	ADP
fnp-4682	211	14	control	control	NOUN
fnp-4682	211	15	xenografts	xenograft	NOUN
fnp-4682	211	16	)	)	PUNCT
fnp-4682	211	17	showed	show	VERB
fnp-4682	211	18	expression	expression	NOUN
fnp-4682	211	19	of	of	ADP
fnp-4682	211	20	cryptic	cryptic	ADJ
fnp-4682	211	21	exons	exon	NOUN
fnp-4682	211	22	in	in	ADP
fnp-4682	211	23	tdp-43	tdp-43	NOUN
fnp-4682	211	24	-	-	PUNCT
fnp-4682	211	25	regulated	regulate	VERB
fnp-4682	211	26	mrnas	mrna	NOUN
fnp-4682	211	27	,	,	PUNCT
fnp-4682	211	28	indicative	indicative	ADJ
fnp-4682	211	29	of	of	ADP
fnp-4682	211	30	functional	functional	ADJ
fnp-4682	211	31	tdp-43	tdp-43	NOUN
fnp-4682	211	32	deficiency	deficiency	NOUN
fnp-4682	211	33	.	.	PUNCT
fnp-4682	212	1	(	(	PUNCT
fnp-4682	212	2	tdp-43	tdp-43	PROPN
fnp-4682	212	3	is	be	AUX
fnp-4682	212	4	an	an	DET
fnp-4682	212	5	rna	rna	NOUN
fnp-4682	212	6	-	-	PUNCT
fnp-4682	212	7	binding	bind	VERB
fnp-4682	212	8	protein	protein	NOUN
fnp-4682	212	9	that	that	PRON
fnp-4682	212	10	maintains	maintain	VERB
fnp-4682	212	11	the	the	DET
fnp-4682	212	12	health	health	NOUN
fnp-4682	212	13	of	of	ADP
fnp-4682	212	14	the	the	DET
fnp-4682	212	15	transcriptome	transcriptome	NOUN
fnp-4682	212	16	by	by	ADP
fnp-4682	212	17	repressing	repress	VERB
fnp-4682	212	18	incorporation	incorporation	NOUN
fnp-4682	212	19	of	of	ADP
fnp-4682	212	20	non	non	ADJ
fnp-4682	212	21	-	-	ADJ
fnp-4682	212	22	conserved	conserved	ADJ
fnp-4682	212	23	cryptic	cryptic	ADJ
fnp-4682	212	24	exons	exon	NOUN
fnp-4682	212	25	during	during	ADP
fnp-4682	212	26	pre	pre	ADJ
fnp-4682	212	27	-	-	ADJ
fnp-4682	212	28	mrna	mrna	ADJ
fnp-4682	212	29	splicing	splicing	NOUN
fnp-4682	212	30	;	;	PUNCT
fnp-4682	212	31	cryptic	cryptic	ADJ
fnp-4682	212	32	exon	exon	NOUN
fnp-4682	212	33	expression	expression	NOUN
fnp-4682	212	34	in	in	ADP
fnp-4682	212	35	the	the	DET
fnp-4682	212	36	tdp-43	tdp-43	NOUN
fnp-4682	212	37	-	-	PUNCT
fnp-4682	212	38	regulated	regulated	ADJ
fnp-4682	212	39	,	,	PUNCT
fnp-4682	212	40	muscle	muscle	NOUN
fnp-4682	212	41	-	-	PUNCT
fnp-4682	212	42	specific	specific	ADJ
fnp-4682	212	43	mrna	mrna	NOUN
fnp-4682	212	44	transcripts	transcript	NOUN
fnp-4682	212	45	was	be	AUX
fnp-4682	212	46	84	84	NUM
fnp-4682	212	47	%	%	NOUN
fnp-4682	212	48	sensitive	sensitive	ADJ
fnp-4682	212	49	and	and	CCONJ
fnp-4682	212	50	99	99	NUM
fnp-4682	212	51	%	%	NOUN
fnp-4682	212	52	specific	specific	ADJ
fnp-4682	212	53	marker	marker	NOUN
fnp-4682	212	54	of	of	ADP
fnp-4682	212	55	sibm	sibm	NOUN
fnp-4682	212	56	in	in	ADP
fnp-4682	212	57	the	the	DET
fnp-4682	212	58	cohort	cohort	NOUN
fnp-4682	212	59	of	of	ADP
fnp-4682	212	60	119	119	NUM
fnp-4682	212	61	myositis	myositis	NOUN
fnp-4682	212	62	patients	patient	NOUN
fnp-4682	212	63	enrolled	enrol	VERB
fnp-4682	212	64	in	in	ADP
fnp-4682	212	65	this	this	DET
fnp-4682	212	66	study	study	NOUN
fnp-4682	212	67	)	)	PUNCT
fnp-4682	212	68	.	.	PUNCT
fnp-4682	213	1	having	having	AUX
fnp-4682	213	2	developed	develop	VERB
fnp-4682	213	3	the	the	DET
fnp-4682	213	4	xenograft	xenograft	PROPN
fnp-4682	213	5	sibm	sibm	PROPN
fnp-4682	213	6	model	model	PROPN
fnp-4682	213	7	,	,	PUNCT
fnp-4682	213	8	britson	britson	PROPN
fnp-4682	213	9	et	et	PROPN
fnp-4682	213	10	al	al	PROPN
fnp-4682	213	11	.	.	PROPN
fnp-4682	213	12	used	use	VERB
fnp-4682	213	13	to	to	ADP
fnp-4682	213	14	it	it	PRON
fnp-4682	213	15	to	to	PART
fnp-4682	213	16	evaluate	evaluate	VERB
fnp-4682	213	17	whether	whether	SCONJ
fnp-4682	213	18	treatment	treatment	NOUN
fnp-4682	213	19	with	with	ADP
fnp-4682	213	20	monoclonal	monoclonal	NOUN
fnp-4682	213	21	anti	anti	ADJ
fnp-4682	213	22	-	-	ADJ
fnp-4682	213	23	cd3	cd3	ADJ
fnp-4682	213	24	antibody	antibody	NOUN
fnp-4682	213	25	okt3	okt3	NOUN
fnp-4682	213	26	would	would	AUX
fnp-4682	213	27	improve	improve	VERB
fnp-4682	213	28	various	various	ADJ
fnp-4682	213	29	aspects	aspect	NOUN
fnp-4682	213	30	of	of	ADP
fnp-4682	213	31	sibm	sibm	NOUN
fnp-4682	213	32	pathology	pathology	PROPN
fnp-4682	213	33	.	.	PUNCT
fnp-4682	214	1	the	the	DET
fnp-4682	214	2	okt3	okt3	PROPN
fnp-4682	214	3	treatment	treatment	NOUN
fnp-4682	214	4	,	,	PUNCT
fnp-4682	214	5	which	which	PRON
fnp-4682	214	6	almost	almost	ADV
fnp-4682	214	7	completely	completely	ADV
fnp-4682	214	8	depleted	deplete	VERB
fnp-4682	214	9	t	t	NOUN
fnp-4682	214	10	cells	cell	NOUN
fnp-4682	214	11	and	and	CCONJ
fnp-4682	214	12	significantly	significantly	ADV
fnp-4682	214	13	reduced	reduce	VERB
fnp-4682	214	14	the	the	DET
fnp-4682	214	15	number	number	NOUN
fnp-4682	214	16	of	of	ADP
fnp-4682	214	17	klrg1	klrg1	NOUN
fnp-4682	214	18	-	-	PUNCT
fnp-4682	214	19	positive	positive	ADJ
fnp-4682	214	20	cells	cell	NOUN
fnp-4682	214	21	in	in	ADP
fnp-4682	214	22	sibm	sibm	PROPN
fnp-4682	214	23	xenografts	xenografts	PROPN
fnp-4682	214	24	after	after	ADP
fnp-4682	214	25	4	4	NUM
fnp-4682	214	26	months	month	NOUN
fnp-4682	214	27	of	of	ADP
fnp-4682	214	28	weekly	weekly	ADJ
fnp-4682	214	29	infusions	infusion	NOUN
fnp-4682	214	30	,	,	PUNCT
fnp-4682	214	31	led	lead	VERB
fnp-4682	214	32	to	to	ADP
fnp-4682	214	33	a	a	DET
fnp-4682	214	34	significant	significant	ADJ
fnp-4682	214	35	decrease	decrease	NOUN
fnp-4682	214	36	in	in	ADP
fnp-4682	214	37	the	the	DET
fnp-4682	214	38	extent	extent	NOUN
fnp-4682	214	39	of	of	ADP
fnp-4682	214	40	mhc	mhc	PROPN
fnp-4682	214	41	-	-	PUNCT
fnp-4682	214	42	i	i	PRON
fnp-4682	214	43	upregulation	upregulation	NOUN
fnp-4682	214	44	;	;	PUNCT
fnp-4682	214	45	however	however	ADV
fnp-4682	214	46	,	,	PUNCT
fnp-4682	214	47	it	it	PRON
fnp-4682	214	48	had	have	VERB
fnp-4682	214	49	no	no	DET
fnp-4682	214	50	significant	significant	ADJ
fnp-4682	214	51	effect	effect	NOUN
fnp-4682	214	52	on	on	ADP
fnp-4682	214	53	myodegenerative	myodegenerative	ADJ
fnp-4682	214	54	sibm	sibm	PROPN
fnp-4682	214	55	features	feature	NOUN
fnp-4682	214	56	(	(	PUNCT
fnp-4682	214	57	cox	cox	NOUN
fnp-4682	214	58	-	-	PUNCT
fnp-4682	214	59	negative	negative	ADJ
fnp-4682	214	60	fibers	fiber	NOUN
fnp-4682	214	61	,	,	PUNCT
fnp-4682	214	62	rimmed	rimmed	ADJ
fnp-4682	214	63	vacuoles	vacuole	NOUN
fnp-4682	214	64	,	,	PUNCT
fnp-4682	214	65	and	and	CCONJ
fnp-4682	214	66	p62	p62	NOUN
fnp-4682	214	67	-	-	PUNCT
fnp-4682	214	68	positive	positive	ADJ
fnp-4682	214	69	protein	protein	NOUN
fnp-4682	214	70	aggregates	aggregate	NOUN
fnp-4682	214	71	)	)	PUNCT
fnp-4682	214	72	.	.	PUNCT
fnp-4682	215	1	in	in	ADP
fnp-4682	215	2	addition	addition	NOUN
fnp-4682	215	3	,	,	PUNCT
fnp-4682	215	4	there	there	PRON
fnp-4682	215	5	was	be	VERB
fnp-4682	215	6	no	no	DET
fnp-4682	215	7	change	change	NOUN
fnp-4682	215	8	in	in	ADP
fnp-4682	215	9	the	the	DET
fnp-4682	215	10	aberrant	aberrant	ADJ
fnp-4682	215	11	expression	expression	NOUN
fnp-4682	215	12	of	of	ADP
fnp-4682	215	13	cryptic	cryptic	ADJ
fnp-4682	215	14	exons	exon	NOUN
fnp-4682	215	15	.	.	PUNCT
fnp-4682	216	1	these	these	PRON
fnp-4682	216	2	results	result	VERB
fnp-4682	216	3	quite	quite	ADV
fnp-4682	216	4	definitively	definitively	ADV
fnp-4682	216	5	demonstrate	demonstrate	VERB
fnp-4682	216	6	that	that	SCONJ
fnp-4682	216	7	myodegenerative	myodegenerative	ADJ
fnp-4682	216	8	pathology	pathology	NOUN
fnp-4682	216	9	is	be	AUX
fnp-4682	216	10	intrinsic	intrinsic	ADJ
fnp-4682	216	11	to	to	ADP
fnp-4682	216	12	sibm	sibm	NOUN
fnp-4682	216	13	muscle	muscle	NOUN
fnp-4682	216	14	and	and	CCONJ
fnp-4682	216	15	can	can	AUX
fnp-4682	216	16	persist	persist	VERB
fnp-4682	216	17	independent	independent	ADJ
fnp-4682	216	18	of	of	ADP
fnp-4682	216	19	sustained	sustained	ADJ
fnp-4682	216	20	inflammation	inflammation	NOUN
fnp-4682	216	21	or	or	CCONJ
fnp-4682	216	22	circulating	circulate	VERB
fnp-4682	216	23	factors	factor	NOUN
fnp-4682	216	24	,	,	PUNCT
fnp-4682	216	25	providing	provide	VERB
fnp-4682	216	26	an	an	DET
fnp-4682	216	27	additional	additional	ADJ
fnp-4682	216	28	explanation	explanation	NOUN
fnp-4682	216	29	for	for	ADP
fnp-4682	216	30	refractoriness	refractoriness	NOUN
fnp-4682	216	31	of	of	ADP
fnp-4682	216	32	sibm	sibm	NOUN
fnp-4682	216	33	to	to	ADP
fnp-4682	216	34	standard	standard	ADJ
fnp-4682	216	35	immunosuppressive	immunosuppressive	ADJ
fnp-4682	216	36	treatments	treatment	NOUN
fnp-4682	216	37	,	,	PUNCT
fnp-4682	216	38	but	but	CCONJ
fnp-4682	216	39	also	also	ADV
fnp-4682	216	40	diminishing	diminish	VERB
fnp-4682	216	41	hope	hope	NOUN
fnp-4682	216	42	that	that	SCONJ
fnp-4682	216	43	therapies	therapie	VERB
fnp-4682	216	44	that	that	PRON
fnp-4682	216	45	directly	directly	ADV
fnp-4682	216	46	target	target	VERB
fnp-4682	216	47	klrg1	klrg1	NOUN
fnp-4682	216	48	-	-	PUNCT
fnp-4682	216	49	positive	positive	ADJ
fnp-4682	216	50	temra	temra	NOUN
fnp-4682	216	51	cells	cell	NOUN
fnp-4682	216	52	(	(	PUNCT
fnp-4682	216	53	which	which	PRON
fnp-4682	216	54	are	be	AUX
fnp-4682	216	55	already	already	ADV
fnp-4682	216	56	in	in	ADP
fnp-4682	216	57	development	development	NOUN
fnp-4682	216	58	)	)	PUNCT
fnp-4682	216	59	will	will	AUX
fnp-4682	216	60	significantly	significantly	ADV
fnp-4682	216	61	benefit	benefit	VERB
fnp-4682	216	62	sibm	sibm	NOUN
fnp-4682	216	63	patients	patient	NOUN
fnp-4682	216	64	.	.	PUNCT
fnp-4682	217	1	however	however	ADV
fnp-4682	217	2	,	,	PUNCT
fnp-4682	217	3	it	it	PRON
fnp-4682	217	4	is	be	AUX
fnp-4682	217	5	less	less	ADV
fnp-4682	217	6	clear	clear	ADJ
fnp-4682	217	7	what	what	PRON
fnp-4682	217	8	these	these	DET
fnp-4682	217	9	findings	finding	NOUN
fnp-4682	217	10	mean	mean	VERB
fnp-4682	217	11	for	for	ADP
fnp-4682	217	12	our	our	PRON
fnp-4682	217	13	understanding	understanding	NOUN
fnp-4682	217	14	of	of	ADP
fnp-4682	217	15	sibm	sibm	NOUN
fnp-4682	217	16	pathogenesis	pathogenesis	NOUN
fnp-4682	217	17	:	:	PUNCT
fnp-4682	217	18	while	while	SCONJ
fnp-4682	217	19	the	the	DET
fnp-4682	217	20	authors	author	NOUN
fnp-4682	217	21	of	of	ADP
fnp-4682	217	22	this	this	DET
fnp-4682	217	23	study	study	NOUN
fnp-4682	217	24	favor	favor	VERB
fnp-4682	217	25	a	a	DET
fnp-4682	217	26	model	model	NOUN
fnp-4682	217	27	in	in	ADP
fnp-4682	217	28	which	which	PRON
fnp-4682	217	29	tdp-43	tdp-43	VERB
fnp-4682	217	30	dysfunction	dysfunction	NOUN
fnp-4682	217	31	is	be	AUX
fnp-4682	217	32	an	an	DET
fnp-4682	217	33	early	early	ADJ
fnp-4682	217	34	event	event	NOUN
fnp-4682	217	35	in	in	ADP
fnp-4682	217	36	the	the	DET
fnp-4682	217	37	disease	disease	NOUN
fnp-4682	217	38	progression	progression	NOUN
fnp-4682	217	39	that	that	PRON
fnp-4682	217	40	then	then	ADV
fnp-4682	217	41	drives	drive	VERB
fnp-4682	217	42	aberrant	aberrant	ADJ
fnp-4682	217	43	mrna	mrna	PROPN
fnp-4682	217	44	splicing	splicing	NOUN
fnp-4682	217	45	,	,	PUNCT
fnp-4682	217	46	neoantigen	neoantigen	NOUN
fnp-4682	217	47	expression	expression	NOUN
fnp-4682	217	48	,	,	PUNCT
fnp-4682	217	49	and	and	CCONJ
fnp-4682	217	50	secondary	secondary	ADJ
fnp-4682	217	51	inflammation	inflammation	NOUN
fnp-4682	217	52	,	,	PUNCT
fnp-4682	217	53	it	it	PRON
fnp-4682	217	54	is	be	AUX
fnp-4682	217	55	equally	equally	ADV
fnp-4682	217	56	possible	possible	ADJ
fnp-4682	217	57	that	that	SCONJ
fnp-4682	217	58	chronic	chronic	ADJ
fnp-4682	217	59	inflammation	inflammation	NOUN
fnp-4682	217	60	within	within	ADP
fnp-4682	217	61	the	the	DET
fnp-4682	217	62	human	human	ADJ
fnp-4682	217	63	xenograft	xenograft	NOUN
fnp-4682	217	64	donor	donor	PROPN
fnp-4682	217	65	prior	prior	ADV
fnp-4682	217	66	to	to	ADP
fnp-4682	217	67	the	the	DET
fnp-4682	217	68	biopsy	biopsy	NOUN
fnp-4682	217	69	(	(	PUNCT
fnp-4682	217	70	and/or	and/or	CCONJ
fnp-4682	217	71	within	within	ADP
fnp-4682	217	72	the	the	DET
fnp-4682	217	73	early	early	ADJ
fnp-4682	217	74	xenograft	xenograft	NOUN
fnp-4682	217	75	,	,	PUNCT
fnp-4682	217	76	prior	prior	ADV
fnp-4682	217	77	to	to	ADP
fnp-4682	217	78	the	the	DET
fnp-4682	217	79	okt	okt	PROPN
fnp-4682	217	80	treatment	treatment	NOUN
fnp-4682	217	81	)	)	PUNCT
fnp-4682	218	1	leads	lead	VERB
fnp-4682	218	2	to	to	ADP
fnp-4682	218	3	genetic	genetic	ADJ
fnp-4682	218	4	and/or	and/or	CCONJ
fnp-4682	218	5	epigenetic	epigenetic	ADJ
fnp-4682	218	6	alterations	alteration	NOUN
fnp-4682	218	7	in	in	ADP
fnp-4682	218	8	satellite	satellite	NOUN
fnp-4682	218	9	cells	cell	NOUN
fnp-4682	218	10	,	,	PUNCT
fnp-4682	218	11	which	which	PRON
fnp-4682	218	12	then	then	ADV
fnp-4682	218	13	recapitulate	recapitulate	VERB
fnp-4682	218	14	tdp-43	tdp-43	ADP
fnp-4682	218	15	dysfunction	dysfunction	NOUN
fnp-4682	218	16	and	and	CCONJ
fnp-4682	218	17	myodegenerative	myodegenerative	ADJ
fnp-4682	218	18	changes	change	NOUN
fnp-4682	218	19	in	in	ADP
fnp-4682	218	20	newly	newly	ADV
fnp-4682	218	21	formed	form	VERB
fnp-4682	218	22	muscle	muscle	NOUN
fnp-4682	218	23	fibers	fiber	NOUN
fnp-4682	218	24	.	.	PUNCT
fnp-4682	219	1	additional	additional	ADJ
fnp-4682	219	2	work	work	NOUN
fnp-4682	219	3	will	will	AUX
fnp-4682	219	4	be	be	AUX
fnp-4682	219	5	required	require	VERB
fnp-4682	219	6	to	to	PART
fnp-4682	219	7	distinguish	distinguish	VERB
fnp-4682	219	8	between	between	ADP
fnp-4682	219	9	these	these	DET
fnp-4682	219	10	two	two	NUM
fnp-4682	219	11	models	model	NOUN
fnp-4682	219	12	of	of	ADP
fnp-4682	219	13	sibm	sibm	NOUN
fnp-4682	219	14	pathogenesis	pathogenesis	NOUN
fnp-4682	219	15	;	;	PUNCT
fnp-4682	219	16	in	in	ADP
fnp-4682	219	17	particular	particular	ADJ
fnp-4682	219	18	,	,	PUNCT
fnp-4682	219	19	it	it	PRON
fnp-4682	219	20	should	should	AUX
fnp-4682	219	21	be	be	AUX
fnp-4682	219	22	established	establish	VERB
fnp-4682	219	23	whether	whether	SCONJ
fnp-4682	219	24	aberrant	aberrant	ADJ
fnp-4682	219	25	expression	expression	NOUN
fnp-4682	219	26	of	of	ADP
fnp-4682	219	27	tdp-43	tdp-43	NOUN
fnp-4682	219	28	-	-	PUNCT
fnp-4682	219	29	regulated	regulate	VERB
fnp-4682	219	30	cryptic	cryptic	ADJ
fnp-4682	219	31	exons	exon	NOUN
fnp-4682	219	32	is	be	AUX
fnp-4682	219	33	also	also	ADV
fnp-4682	219	34	present	present	ADJ
fnp-4682	219	35	in	in	ADP
fnp-4682	219	36	hereditary	hereditary	ADJ
fnp-4682	219	37	inclusion	inclusion	NOUN
fnp-4682	219	38	body	body	NOUN
fnp-4682	219	39	myopathies	myopathy	NOUN
fnp-4682	219	40	,	,	PUNCT
fnp-4682	219	41	which	which	PRON
fnp-4682	219	42	show	show	VERB
fnp-4682	219	43	sibm	sibm	NOUN
fnp-4682	219	44	-	-	PUNCT
fnp-4682	219	45	like	like	ADJ
fnp-4682	219	46	myodegenerative	myodegenerative	ADJ
fnp-4682	219	47	features	feature	NOUN
fnp-4682	219	48	but	but	CCONJ
fnp-4682	219	49	lack	lack	VERB
fnp-4682	219	50	inflammation	inflammation	NOUN
fnp-4682	219	51	.	.	PUNCT
fnp-4682	220	1	interestingly	interestingly	ADV
fnp-4682	220	2	,	,	PUNCT
fnp-4682	220	3	the	the	DET
fnp-4682	220	4	results	result	NOUN
fnp-4682	220	5	of	of	ADP
fnp-4682	220	6	another	another	DET
fnp-4682	220	7	2022	2022	NUM
fnp-4682	220	8	paper	paper	NOUN
fnp-4682	220	9	provide	provide	VERB
fnp-4682	220	10	support	support	NOUN
fnp-4682	220	11	for	for	ADP
fnp-4682	220	12	inflammation	inflammation	NOUN
fnp-4682	220	13	as	as	ADP
fnp-4682	220	14	an	an	DET
fnp-4682	220	15	early	early	ADJ
fnp-4682	220	16	event	event	NOUN
fnp-4682	220	17	in	in	ADP
fnp-4682	220	18	sibm	sibm	NOUN
fnp-4682	220	19	disease	disease	NOUN
fnp-4682	220	20	progression	progression	NOUN
fnp-4682	220	21	(	(	PUNCT
fnp-4682	220	22	kleefeld	kleefeld	VERB
fnp-4682	220	23	et	et	PROPN
fnp-4682	220	24	al	al	PROPN
fnp-4682	220	25	.	.	PROPN
fnp-4682	220	26	,	,	PUNCT
fnp-4682	220	27	2022	2022	NUM
fnp-4682	220	28	)	)	PUNCT
fnp-4682	220	29	.	.	PUNCT
fnp-4682	221	1	in	in	ADP
fnp-4682	221	2	their	their	PRON
fnp-4682	221	3	cross	cross	ADJ
fnp-4682	221	4	-	-	ADJ
fnp-4682	221	5	sectional	sectional	ADJ
fnp-4682	221	6	study	study	NOUN
fnp-4682	221	7	,	,	PUNCT
fnp-4682	221	8	kleefeld	kleefeld	VERB
fnp-4682	221	9	and	and	CCONJ
fnp-4682	221	10	colleagues	colleague	NOUN
fnp-4682	221	11	examined	examine	VERB
fnp-4682	221	12	the	the	DET
fnp-4682	221	13	similarities	similarity	NOUN
fnp-4682	221	14	and	and	CCONJ
fnp-4682	221	15	differences	difference	NOUN
fnp-4682	221	16	between	between	ADP
fnp-4682	221	17	polymyositis	polymyositis	PROPN
fnp-4682	221	18	with	with	ADP
fnp-4682	221	19	mitochondrial	mitochondrial	ADJ
fnp-4682	221	20	pathology	pathology	NOUN
fnp-4682	221	21	(	(	PUNCT
fnp-4682	221	22	pm	pm	NOUN
fnp-4682	221	23	-	-	PUNCT
fnp-4682	221	24	mito	mito	NOUN
fnp-4682	221	25	)	)	PUNCT
fnp-4682	221	26	and	and	CCONJ
fnp-4682	221	27	sibm	sibm	NOUN
fnp-4682	221	28	.	.	PUNCT
fnp-4682	222	1	in	in	ADP
fnp-4682	222	2	contrast	contrast	NOUN
fnp-4682	222	3	to	to	ADP
fnp-4682	222	4	sibm	sibm	PROPN
fnp-4682	222	5	,	,	PUNCT
fnp-4682	222	6	which	which	PRON
fnp-4682	222	7	has	have	VERB
fnp-4682	222	8	a	a	DET
fnp-4682	222	9	distinctive	distinctive	ADJ
fnp-4682	222	10	clinical	clinical	ADJ
fnp-4682	222	11	phenotype	phenotype	NOUN
fnp-4682	222	12	,	,	PUNCT
fnp-4682	222	13	pm	pm	PROPN
fnp-4682	222	14	-	-	PUNCT
fnp-4682	222	15	mito	mito	PROPN
fnp-4682	222	16	is	be	AUX
fnp-4682	222	17	not	not	PART
fnp-4682	222	18	a	a	DET
fnp-4682	222	19	clinically	clinically	ADV
fnp-4682	222	20	well	well	ADV
fnp-4682	222	21	-	-	PUNCT
fnp-4682	222	22	defined	define	VERB
fnp-4682	222	23	entity	entity	NOUN
fnp-4682	222	24	;	;	PUNCT
fnp-4682	222	25	pathologically	pathologically	ADV
fnp-4682	222	26	,	,	PUNCT
fnp-4682	222	27	however	however	ADV
fnp-4682	222	28	,	,	PUNCT
fnp-4682	222	29	it	it	PRON
fnp-4682	222	30	shows	show	VERB
fnp-4682	222	31	some	some	DET
fnp-4682	222	32	sibm	sibm	NOUN
fnp-4682	222	33	-	-	PUNCT
fnp-4682	222	34	like	like	ADJ
fnp-4682	222	35	features	feature	NOUN
fnp-4682	222	36	(	(	PUNCT
fnp-4682	222	37	lymphocytic	lymphocytic	ADJ
fnp-4682	222	38	endomysial	endomysial	ADJ
fnp-4682	222	39	inflammation	inflammation	NOUN
fnp-4682	222	40	,	,	PUNCT
fnp-4682	222	41	muscle	muscle	NOUN
fnp-4682	222	42	fiber	fiber	NOUN
fnp-4682	222	43	invasion	invasion	NOUN
fnp-4682	222	44	by	by	ADP
fnp-4682	222	45	inflammatory	inflammatory	ADJ
fnp-4682	222	46	cells	cell	NOUN
fnp-4682	222	47	,	,	PUNCT
fnp-4682	222	48	and	and	CCONJ
fnp-4682	222	49	mitochondrial	mitochondrial	ADJ
fnp-4682	222	50	pathology	pathology	NOUN
fnp-4682	222	51	/	/	SYM
fnp-4682	222	52	cox	cox	PROPN
fnp-4682	222	53	-	-	PUNCT
fnp-4682	222	54	deficient	deficient	ADJ
fnp-4682	222	55	fibers	fiber	NOUN
fnp-4682	222	56	)	)	PUNCT
fnp-4682	222	57	but	but	CCONJ
fnp-4682	222	58	lacks	lack	VERB
fnp-4682	222	59	rimmed	rimmed	ADJ
fnp-4682	222	60	vacuoles	vacuole	NOUN
fnp-4682	222	61	,	,	PUNCT
fnp-4682	222	62	chronic	chronic	ADJ
fnp-4682	222	63	myopathic	myopathic	ADJ
fnp-4682	222	64	changes	change	NOUN
fnp-4682	222	65	,	,	PUNCT
fnp-4682	222	66	and	and	CCONJ
fnp-4682	222	67	p62or	p62or	ADJ
fnp-4682	222	68	tdp-43	tdp-43	NOUN
fnp-4682	222	69	-	-	PUNCT
fnp-4682	222	70	positive	positive	ADJ
fnp-4682	222	71	protein	protein	NOUN
fnp-4682	222	72	aggregates	aggregate	NOUN
fnp-4682	222	73	(	(	PUNCT
fnp-4682	222	74	blume	blume	PROPN
fnp-4682	222	75	et	et	PROPN
fnp-4682	222	76	al	al	PROPN
fnp-4682	222	77	.	.	PROPN
fnp-4682	222	78	,	,	PUNCT
fnp-4682	222	79	1997	1997	NUM
fnp-4682	222	80	;	;	PUNCT
fnp-4682	222	81	hiniker	hiniker	PART
fnp-4682	222	82	et	et	PROPN
fnp-4682	222	83	al	al	PROPN
fnp-4682	222	84	.	.	PROPN
fnp-4682	222	85	,	,	PUNCT
fnp-4682	222	86	2013	2013	NUM
fnp-4682	222	87	)	)	PUNCT
fnp-4682	222	88	.	.	PUNCT
fnp-4682	223	1	although	although	SCONJ
fnp-4682	223	2	most	most	ADJ
fnp-4682	223	3	patients	patient	NOUN
fnp-4682	223	4	with	with	ADP
fnp-4682	223	5	pm	pm	PROPN
fnp-4682	223	6	-	-	PUNCT
fnp-4682	223	7	mito	mito	PROPN
fnp-4682	223	8	over	over	ADP
fnp-4682	223	9	time	time	NOUN
fnp-4682	223	10	progress	progress	NOUN
fnp-4682	223	11	to	to	PART
fnp-4682	223	12	sibm	sibm	VERB
fnp-4682	223	13	,	,	PUNCT
fnp-4682	223	14	at	at	ADP
fnp-4682	223	15	least	least	ADJ
fnp-4682	223	16	partial	partial	ADJ
fnp-4682	223	17	response	response	NOUN
fnp-4682	223	18	to	to	ADP
fnp-4682	223	19	immunosuppression	immunosuppression	NOUN
fnp-4682	223	20	has	have	AUX
fnp-4682	223	21	been	be	AUX
fnp-4682	223	22	observed	observe	VERB
fnp-4682	223	23	in	in	ADP
fnp-4682	223	24	a	a	DET
fnp-4682	223	25	subset	subset	NOUN
fnp-4682	223	26	of	of	ADP
fnp-4682	223	27	cases	case	NOUN
fnp-4682	223	28	(	(	PUNCT
fnp-4682	223	29	levine	levine	NOUN
fnp-4682	223	30	and	and	CCONJ
fnp-4682	223	31	pestronk	pestronk	PROPN
fnp-4682	223	32	,	,	PUNCT
fnp-4682	223	33	1998	1998	NUM
fnp-4682	223	34	;	;	PUNCT
fnp-4682	223	35	winkler	winkler	PROPN
fnp-4682	223	36	et	et	PROPN
fnp-4682	223	37	al	al	PROPN
fnp-4682	223	38	.	.	PROPN
fnp-4682	223	39	,	,	PUNCT
fnp-4682	223	40	2021	2021	NUM
fnp-4682	223	41	)	)	PUNCT
fnp-4682	223	42	,	,	PUNCT
fnp-4682	223	43	raising	raise	VERB
fnp-4682	223	44	the	the	DET
fnp-4682	223	45	possibility	possibility	NOUN
fnp-4682	223	46	that	that	SCONJ
fnp-4682	223	47	pm	pm	PROPN
fnp-4682	223	48	-	-	PUNCT
fnp-4682	223	49	mito	mito	PROPN
fnp-4682	223	50	and	and	CCONJ
fnp-4682	223	51	sibm	sibm	PROPN
fnp-4682	223	52	exist	exist	VERB
fnp-4682	223	53	on	on	ADP
fnp-4682	223	54	a	a	DET
fnp-4682	223	55	spectrum	spectrum	NOUN
fnp-4682	223	56	,	,	PUNCT
fnp-4682	223	57	with	with	ADP
fnp-4682	223	58	pm	pm	PROPN
fnp-4682	223	59	-	-	PUNCT
fnp-4682	223	60	mito	mito	PROPN
fnp-4682	223	61	an	an	DET
fnp-4682	223	62	early	early	ADJ
fnp-4682	223	63	–	–	PUNCT
fnp-4682	223	64	and	and	CCONJ
fnp-4682	223	65	potentially	potentially	ADV
fnp-4682	223	66	treatable	treatable	ADJ
fnp-4682	223	67	–	–	PUNCT
fnp-4682	223	68	stage	stage	NOUN
fnp-4682	223	69	of	of	ADP
fnp-4682	223	70	sibm	sibm	NOUN
fnp-4682	223	71	.	.	PUNCT
fnp-4682	224	1	the	the	DET
fnp-4682	224	2	findings	finding	NOUN
fnp-4682	224	3	reported	report	VERB
fnp-4682	224	4	by	by	ADP
fnp-4682	224	5	kleefeld	kleefeld	PROPN
fnp-4682	224	6	et	et	PROPN
fnp-4682	224	7	al	al	PROPN
fnp-4682	224	8	.	.	PUNCT
fnp-4682	224	9	support	support	VERB
fnp-4682	224	10	this	this	DET
fnp-4682	224	11	model	model	NOUN
fnp-4682	224	12	:	:	PUNCT
fnp-4682	224	13	they	they	PRON
fnp-4682	224	14	found	find	VERB
fnp-4682	224	15	an	an	DET
fnp-4682	224	16	essentially	essentially	ADV
fnp-4682	224	17	identical	identical	ADJ
fnp-4682	224	18	inflammatory	inflammatory	ADJ
fnp-4682	224	19	molecular	molecular	ADJ
fnp-4682	224	20	signature	signature	NOUN
fnp-4682	224	21	in	in	ADP
fnp-4682	224	22	pm	pm	PROPN
fnp-4682	224	23	-	-	PUNCT
fnp-4682	224	24	mito	mito	PROPN
fnp-4682	224	25	and	and	CCONJ
fnp-4682	224	26	sibm	sibm	PROPN
fnp-4682	224	27	biopsies	biopsy	NOUN
fnp-4682	224	28	,	,	PUNCT
fnp-4682	224	29	with	with	ADP
fnp-4682	224	30	greater	great	ADJ
fnp-4682	224	31	activation	activation	NOUN
fnp-4682	224	32	of	of	ADP
fnp-4682	224	33	type	type	NOUN
fnp-4682	224	34	ii	ii	NOUN
fnp-4682	224	35	than	than	ADP
fnp-4682	224	36	type	type	NOUN
fnp-4682	224	37	i	i	PRON
fnp-4682	224	38	interferon	interferon	ADJ
fnp-4682	224	39	response	response	NOUN
fnp-4682	224	40	and	and	CCONJ
fnp-4682	224	41	expression	expression	NOUN
fnp-4682	224	42	of	of	ADP
fnp-4682	224	43	cryptic	cryptic	ADJ
fnp-4682	224	44	exons	exon	NOUN
fnp-4682	224	45	in	in	ADP
fnp-4682	224	46	both	both	DET
fnp-4682	224	47	sets	set	NOUN
fnp-4682	224	48	of	of	ADP
fnp-4682	224	49	cases	case	NOUN
fnp-4682	224	50	(	(	PUNCT
fnp-4682	224	51	although	although	SCONJ
fnp-4682	224	52	frequency	frequency	NOUN
fnp-4682	224	53	of	of	ADP
fnp-4682	224	54	cryptic	cryptic	ADJ
fnp-4682	224	55	exon	exon	NOUN
fnp-4682	224	56	expression	expression	NOUN
fnp-4682	224	57	was	be	AUX
fnp-4682	224	58	greater	great	ADJ
fnp-4682	224	59	in	in	ADP
fnp-4682	224	60	sibm	sibm	NOUN
fnp-4682	224	61	than	than	ADP
fnp-4682	224	62	pm	pm	NOUN
fnp-4682	224	63	-	-	PUNCT
fnp-4682	224	64	mito	mito	PROPN
fnp-4682	224	65	biopsies	biopsy	NOUN
fnp-4682	224	66	)	)	PUNCT
fnp-4682	224	67	.	.	PUNCT
fnp-4682	225	1	in	in	ADP
fnp-4682	225	2	contrast	contrast	NOUN
fnp-4682	225	3	to	to	ADP
fnp-4682	225	4	these	these	DET
fnp-4682	225	5	similarities	similarity	NOUN
fnp-4682	225	6	,	,	PUNCT
fnp-4682	225	7	klrg1	klrg1	NOUN
fnp-4682	225	8	and	and	CCONJ
fnp-4682	225	9	gbp6	gbp6	PROPN
fnp-4682	225	10	(	(	PUNCT
fnp-4682	225	11	guanylate	guanylate	ADJ
fnp-4682	225	12	binding	bind	VERB
fnp-4682	225	13	protein	protein	NOUN
fnp-4682	225	14	family	family	NOUN
fnp-4682	225	15	member	member	NOUN
fnp-4682	225	16	6	6	NUM
fnp-4682	225	17	)	)	PUNCT
fnp-4682	225	18	genes	gene	NOUN
fnp-4682	225	19	were	be	AUX
fnp-4682	225	20	differentially	differentially	ADV
fnp-4682	225	21	expressed	express	VERB
fnp-4682	225	22	,	,	PUNCT
fnp-4682	225	23	with	with	ADP
fnp-4682	225	24	both	both	CCONJ
fnp-4682	225	25	klrg1	klrg1	NOUN
fnp-4682	225	26	and	and	CCONJ
fnp-4682	225	27	gbp6	gbp6	PROPN
fnp-4682	225	28	mrna	mrna	PROPN
fnp-4682	225	29	upregulation	upregulation	PROPN
fnp-4682	225	30	detectable	detectable	ADJ
fnp-4682	225	31	only	only	ADV
fnp-4682	225	32	in	in	ADP
fnp-4682	225	33	sibm	sibm	PROPN
fnp-4682	225	34	biopsies	biopsy	NOUN
fnp-4682	225	35	.	.	PUNCT
fnp-4682	226	1	in	in	ADP
fnp-4682	226	2	agreement	agreement	NOUN
fnp-4682	226	3	with	with	ADP
fnp-4682	226	4	this	this	DET
fnp-4682	226	5	finding	finding	NOUN
fnp-4682	226	6	,	,	PUNCT
fnp-4682	226	7	gbp6	gbp6	NOUN
fnp-4682	226	8	-	-	PUNCT
fnp-4682	226	9	positive	positive	ADJ
fnp-4682	226	10	macrophages	macrophage	NOUN
fnp-4682	226	11	,	,	PUNCT
fnp-4682	226	12	gbp6	gbp6	NOUN
fnp-4682	226	13	-	-	PUNCT
fnp-4682	226	14	expressing	express	VERB
fnp-4682	226	15	myofibers	myofiber	NOUN
fnp-4682	226	16	,	,	PUNCT
fnp-4682	226	17	and	and	CCONJ
fnp-4682	226	18	klrg1	klrg1	NOUN
fnp-4682	226	19	-	-	PUNCT
fnp-4682	226	20	positive	positive	ADJ
fnp-4682	226	21	t	t	NOUN
fnp-4682	226	22	cells	cell	NOUN
fnp-4682	226	23	were	be	AUX
fnp-4682	226	24	significantly	significantly	ADV
fnp-4682	226	25	more	more	ADV
fnp-4682	226	26	abundant	abundant	ADJ
fnp-4682	226	27	in	in	ADP
fnp-4682	226	28	sibm	sibm	NOUN
fnp-4682	226	29	than	than	ADP
fnp-4682	226	30	pm	pm	NOUN
fnp-4682	226	31	-	-	PUNCT
fnp-4682	226	32	mito	mito	PROPN
fnp-4682	226	33	samples	sample	NOUN
fnp-4682	226	34	.	.	PUNCT
fnp-4682	227	1	overall	overall	ADJ
fnp-4682	227	2	,	,	PUNCT
fnp-4682	227	3	most	most	ADJ
fnp-4682	227	4	differences	difference	NOUN
fnp-4682	227	5	between	between	ADP
fnp-4682	227	6	pm	pm	PROPN
fnp-4682	227	7	-	-	PUNCT
fnp-4682	227	8	mito	mito	PROPN
fnp-4682	227	9	and	and	CCONJ
fnp-4682	227	10	sibm	sibm	PROPN
fnp-4682	227	11	biopsies	biopsy	NOUN
fnp-4682	227	12	were	be	AUX
fnp-4682	227	13	quantitative	quantitative	ADJ
fnp-4682	227	14	rather	rather	ADV
fnp-4682	227	15	than	than	ADP
fnp-4682	227	16	qualitative	qualitative	NOUN
fnp-4682	227	17	,	,	PUNCT
fnp-4682	227	18	with	with	ADP
fnp-4682	227	19	a	a	DET
fnp-4682	227	20	gradient	gradient	NOUN
fnp-4682	227	21	of	of	ADP
fnp-4682	227	22	severity	severity	NOUN
fnp-4682	227	23	observed	observe	VERB
fnp-4682	227	24	even	even	ADV
fnp-4682	227	25	within	within	ADP
fnp-4682	227	26	the	the	DET
fnp-4682	227	27	pm	pm	PROPN
fnp-4682	227	28	-	-	PUNCT
fnp-4682	227	29	mito	mito	PROPN
fnp-4682	227	30	group	group	NOUN
fnp-4682	227	31	(	(	PUNCT
fnp-4682	227	32	which	which	PRON
fnp-4682	227	33	could	could	AUX
fnp-4682	227	34	be	be	AUX
fnp-4682	227	35	histologically	histologically	ADV
fnp-4682	227	36	divided	divide	VERB
fnp-4682	227	37	into	into	ADP
fnp-4682	227	38	“	"	PUNCT
fnp-4682	227	39	mild	mild	ADJ
fnp-4682	227	40	”	"	PUNCT
fnp-4682	227	41	,	,	PUNCT
fnp-4682	227	42	“	"	PUNCT
fnp-4682	227	43	typical	typical	ADJ
fnp-4682	227	44	”	"	PUNCT
fnp-4682	227	45	,	,	PUNCT
fnp-4682	227	46	and	and	CCONJ
fnp-4682	227	47	“	"	PUNCT
fnp-4682	227	48	pre	pre	ADJ
fnp-4682	227	49	-	-	ADJ
fnp-4682	227	50	ibm	ibm	ADJ
fnp-4682	227	51	”	"	PUNCT
fnp-4682	227	52	subgroups	subgroup	NOUN
fnp-4682	227	53	)	)	PUNCT
fnp-4682	227	54	.	.	PUNCT
fnp-4682	228	1	importantly	importantly	ADV
fnp-4682	228	2	,	,	PUNCT
fnp-4682	228	3	this	this	DET
fnp-4682	228	4	progression	progression	NOUN
fnp-4682	228	5	of	of	ADP
fnp-4682	228	6	severity	severity	NOUN
fnp-4682	228	7	was	be	AUX
fnp-4682	228	8	also	also	ADV
fnp-4682	228	9	observed	observe	VERB
fnp-4682	228	10	in	in	ADP
fnp-4682	228	11	serial	serial	ADJ
fnp-4682	228	12	biopsies	biopsy	NOUN
fnp-4682	228	13	from	from	ADP
fnp-4682	228	14	two	two	NUM
fnp-4682	228	15	individuals	individual	NOUN
fnp-4682	228	16	,	,	PUNCT
fnp-4682	228	17	the	the	DET
fnp-4682	228	18	first	first	ADJ
fnp-4682	228	19	showing	show	VERB
fnp-4682	228	20	pm	pm	NOUN
fnp-4682	228	21	-	-	PUNCT
fnp-4682	228	22	mito	mito	PROPN
fnp-4682	228	23	and	and	CCONJ
fnp-4682	228	24	the	the	DET
fnp-4682	228	25	second	second	ADJ
fnp-4682	228	26	(	(	PUNCT
fnp-4682	228	27	5	5	NUM
fnp-4682	228	28	-	-	SYM
fnp-4682	228	29	7	7	NUM
fnp-4682	228	30	years	year	NOUN
fnp-4682	228	31	later	later	ADV
fnp-4682	228	32	)	)	PUNCT
fnp-4682	228	33	sibm	sibm	PROPN
fnp-4682	228	34	.	.	PUNCT
fnp-4682	229	1	based	base	VERB
fnp-4682	229	2	on	on	ADP
fnp-4682	229	3	these	these	DET
fnp-4682	229	4	findings	finding	NOUN
fnp-4682	229	5	,	,	PUNCT
fnp-4682	229	6	kleefeld	kleefeld	VERB
fnp-4682	229	7	and	and	CCONJ
fnp-4682	229	8	colleagues	colleague	NOUN
fnp-4682	229	9	recommended	recommend	VERB
fnp-4682	229	10	that	that	SCONJ
fnp-4682	229	11	pm	pm	NOUN
fnp-4682	229	12	-	-	PUNCT
fnp-4682	229	13	mito	mito	PROPN
fnp-4682	229	14	should	should	AUX
fnp-4682	229	15	be	be	AUX
fnp-4682	229	16	renamed	rename	VERB
fnp-4682	229	17	early	early	ADJ
fnp-4682	229	18	sibm	sibm	NOUN
fnp-4682	229	19	and	and	CCONJ
fnp-4682	229	20	that	that	SCONJ
fnp-4682	229	21	both	both	DET
fnp-4682	229	22	disorders	disorder	NOUN
fnp-4682	229	23	together	together	ADV
fnp-4682	229	24	should	should	AUX
fnp-4682	229	25	be	be	AUX
fnp-4682	229	26	classified	classify	VERB
fnp-4682	229	27	as	as	ADP
fnp-4682	229	28	“	"	PUNCT
fnp-4682	229	29	sibm	sibm	NOUN
fnp-4682	229	30	-	-	PUNCT
fnp-4682	229	31	spectrum	spectrum	NOUN
fnp-4682	229	32	disease	disease	NOUN
fnp-4682	229	33	”	"	PUNCT
fnp-4682	229	34	(	(	PUNCT
fnp-4682	229	35	sibm	sibm	NOUN
fnp-4682	229	36	-	-	PUNCT
fnp-4682	229	37	sd	sd	NOUN
fnp-4682	229	38	)	)	PUNCT
fnp-4682	229	39	.	.	PUNCT
fnp-4682	230	1	in	in	ADP
fnp-4682	230	2	addition	addition	NOUN
fnp-4682	230	3	,	,	PUNCT
fnp-4682	230	4	they	they	PRON
fnp-4682	230	5	suggested	suggest	VERB
fnp-4682	230	6	that	that	SCONJ
fnp-4682	230	7	the	the	DET
fnp-4682	230	8	difference	difference	NOUN
fnp-4682	230	9	in	in	ADP
fnp-4682	230	10	klrg1	klrg1	NOUN
fnp-4682	230	11	expression	expression	NOUN
fnp-4682	230	12	between	between	ADP
fnp-4682	230	13	early	early	ADJ
fnp-4682	230	14	and	and	CCONJ
fnp-4682	230	15	late	late	ADJ
fnp-4682	230	16	sibm	sibm	NOUN
fnp-4682	230	17	stages	stage	NOUN
fnp-4682	230	18	reflected	reflect	VERB
fnp-4682	230	19	disease	disease	NOUN
fnp-4682	230	20	duration	duration	NOUN
fnp-4682	230	21	,	,	PUNCT
fnp-4682	230	22	with	with	ADP
fnp-4682	230	23	emergence	emergence	NOUN
fnp-4682	230	24	of	of	ADP
fnp-4682	230	25	exhausted	exhausted	ADJ
fnp-4682	230	26	t	t	NOUN
fnp-4682	230	27	cells	cell	NOUN
fnp-4682	230	28	a	a	DET
fnp-4682	230	29	consequence	consequence	NOUN
fnp-4682	230	30	of	of	ADP
fnp-4682	230	31	prolonged	prolonged	ADJ
fnp-4682	230	32	inflammation	inflammation	NOUN
fnp-4682	230	33	/	/	SYM
fnp-4682	230	34	antigenic	antigenic	ADJ
fnp-4682	230	35	stimulation	stimulation	NOUN
fnp-4682	230	36	and	and	CCONJ
fnp-4682	230	37	a	a	DET
fnp-4682	230	38	harbinger	harbinger	NOUN
fnp-4682	230	39	of	of	ADP
fnp-4682	230	40	transition	transition	NOUN
fnp-4682	230	41	into	into	ADP
fnp-4682	230	42	a	a	DET
fnp-4682	230	43	therapy	therapy	NOUN
fnp-4682	230	44	-	-	PUNCT
fnp-4682	230	45	resistant	resistant	ADJ
fnp-4682	230	46	end	end	NOUN
fnp-4682	230	47	stage	stage	NOUN
fnp-4682	230	48	of	of	ADP
fnp-4682	230	49	sibm	sibm	NOUN
fnp-4682	230	50	-	-	PUNCT
fnp-4682	230	51	sd	sd	NOUN
fnp-4682	230	52	.	.	PUNCT
fnp-4682	231	1	in	in	ADP
fnp-4682	231	2	agreement	agreement	NOUN
fnp-4682	231	3	with	with	ADP
fnp-4682	231	4	that	that	DET
fnp-4682	231	5	hypothesis	hypothesis	NOUN
fnp-4682	231	6	,	,	PUNCT
fnp-4682	231	7	another	another	DET
fnp-4682	231	8	recent	recent	ADJ
fnp-4682	231	9	study	study	NOUN
fnp-4682	231	10	used	use	VERB
fnp-4682	231	11	“	"	PUNCT
fnp-4682	231	12	deep	deep	ADJ
fnp-4682	231	13	immunophenotyping	immunophenotyping	NOUN
fnp-4682	231	14	”	"	PUNCT
fnp-4682	231	15	of	of	ADP
fnp-4682	231	16	blood	blood	NOUN
fnp-4682	231	17	t	t	PROPN
fnp-4682	231	18	and	and	CCONJ
fnp-4682	231	19	nk	nk	PROPN
fnp-4682	231	20	cells	cell	NOUN
fnp-4682	231	21	from	from	ADP
fnp-4682	231	22	sibm	sibm	NOUN
fnp-4682	231	23	patients	patient	NOUN
fnp-4682	231	24	to	to	PART
fnp-4682	231	25	show	show	VERB
fnp-4682	231	26	that	that	SCONJ
fnp-4682	231	27	increased	increase	VERB
fnp-4682	231	28	cd8	cd8	PROPN
fnp-4682	231	29	+	+	PROPN
fnp-4682	231	30	t	t	PROPN
fnp-4682	231	31	cell	cell	NOUN
fnp-4682	231	32	differentiation	differentiation	NOUN
fnp-4682	231	33	correlated	correlate	VERB
fnp-4682	231	34	with	with	ADP
fnp-4682	231	35	sibm	sibm	NOUN
fnp-4682	231	36	duration	duration	NOUN
fnp-4682	231	37	(	(	PUNCT
fnp-4682	231	38	goyal	goyal	PROPN
fnp-4682	231	39	et	et	PROPN
fnp-4682	231	40	al	al	PROPN
fnp-4682	231	41	.	.	PROPN
fnp-4682	231	42	,	,	PUNCT
fnp-4682	231	43	2022	2022	NUM
fnp-4682	231	44	)	)	PUNCT
fnp-4682	231	45	.	.	PUNCT
fnp-4682	232	1	among	among	ADP
fnp-4682	232	2	many	many	ADJ
fnp-4682	232	3	questions	question	NOUN
fnp-4682	232	4	that	that	PRON
fnp-4682	232	5	still	still	ADV
fnp-4682	232	6	need	need	VERB
fnp-4682	232	7	to	to	PART
fnp-4682	232	8	be	be	AUX
fnp-4682	232	9	answered	answer	VERB
fnp-4682	232	10	is	be	AUX
fnp-4682	232	11	the	the	DET
fnp-4682	232	12	“	"	PUNCT
fnp-4682	232	13	status	status	NOUN
fnp-4682	232	14	”	"	PUNCT
fnp-4682	232	15	of	of	ADP
fnp-4682	232	16	polymyositis	polymyositis	PROPN
fnp-4682	232	17	without	without	ADP
fnp-4682	232	18	mitochondrial	mitochondrial	ADJ
fnp-4682	232	19	abnormalities	abnormality	NOUN
fnp-4682	232	20	,	,	PUNCT
fnp-4682	232	21	which	which	PRON
fnp-4682	232	22	is	be	AUX
fnp-4682	232	23	histologically	histologically	ADV
fnp-4682	232	24	identical	identical	ADJ
fnp-4682	232	25	to	to	ADP
fnp-4682	232	26	pm	pm	VERB
fnp-4682	232	27	-	-	PUNCT
fnp-4682	232	28	mito	mito	PROPN
fnp-4682	232	29	except	except	SCONJ
fnp-4682	232	30	for	for	ADP
fnp-4682	232	31	the	the	DET
fnp-4682	232	32	absence	absence	NOUN
fnp-4682	232	33	of	of	ADP
fnp-4682	232	34	ragged	ragged	ADJ
fnp-4682	232	35	red	red	ADJ
fnp-4682	232	36	and	and	CCONJ
fnp-4682	232	37	cox	cox	PROPN
fnp-4682	232	38	-	-	PUNCT
fnp-4682	232	39	negative	negative	ADJ
fnp-4682	232	40	fibers	fiber	NOUN
fnp-4682	232	41	(	(	PUNCT
fnp-4682	232	42	hiniker	hiniker	ADV
fnp-4682	232	43	et	et	PROPN
fnp-4682	232	44	al	al	PROPN
fnp-4682	232	45	.	.	PROPN
fnp-4682	232	46	,	,	PUNCT
fnp-4682	232	47	2013	2013	NUM
fnp-4682	232	48	)	)	PUNCT
fnp-4682	232	49	.	.	PUNCT
fnp-4682	233	1	it	it	PRON
fnp-4682	233	2	is	be	AUX
fnp-4682	233	3	not	not	PART
fnp-4682	233	4	currently	currently	ADV
fnp-4682	233	5	known	know	VERB
fnp-4682	233	6	whether	whether	SCONJ
fnp-4682	233	7	polymyositis	polymyositis	PROPN
fnp-4682	233	8	is	be	AUX
fnp-4682	233	9	a	a	DET
fnp-4682	233	10	separate	separate	ADJ
fnp-4682	233	11	disease	disease	NOUN
fnp-4682	233	12	,	,	PUNCT
fnp-4682	233	13	or	or	CCONJ
fnp-4682	233	14	an	an	DET
fnp-4682	233	15	even	even	ADV
fnp-4682	233	16	earlier	early	ADJ
fnp-4682	233	17	stage	stage	NOUN
fnp-4682	233	18	of	of	ADP
fnp-4682	233	19	sibm	sibm	NOUN
fnp-4682	233	20	-	-	PUNCT
fnp-4682	233	21	sd	sd	NOUN
fnp-4682	233	22	that	that	PRON
fnp-4682	233	23	can	can	AUX
fnp-4682	233	24	be	be	AUX
fnp-4682	233	25	effectively	effectively	ADV
fnp-4682	233	26	treated	treat	VERB
fnp-4682	233	27	by	by	ADP
fnp-4682	233	28	standard	standard	ADJ
fnp-4682	233	29	immunosuppressive	immunosuppressive	ADJ
fnp-4682	233	30	therapy	therapy	NOUN
fnp-4682	233	31	and	and	CCONJ
fnp-4682	233	32	is	be	AUX
fnp-4682	233	33	therefore	therefore	ADV
fnp-4682	233	34	less	less	ADV
fnp-4682	233	35	likely	likely	ADJ
fnp-4682	233	36	to	to	PART
fnp-4682	233	37	progress	progress	VERB
fnp-4682	233	38	to	to	ADP
fnp-4682	233	39	a	a	DET
fnp-4682	233	40	chronic	chronic	ADJ
fnp-4682	233	41	inflammation	inflammation	NOUN
fnp-4682	233	42	-	-	PUNCT
fnp-4682	233	43	driven	drive	VERB
fnp-4682	233	44	,	,	PUNCT
fnp-4682	233	45	treatment	treatment	NOUN
fnp-4682	233	46	-	-	PUNCT
fnp-4682	233	47	resistant	resistant	ADJ
fnp-4682	233	48	end	end	NOUN
fnp-4682	233	49	stage	stage	NOUN
fnp-4682	233	50	.	.	PUNCT
fnp-4682	234	1	given	give	VERB
fnp-4682	234	2	that	that	DET
fnp-4682	234	3	inflammation	inflammation	NOUN
fnp-4682	234	4	can	can	AUX
fnp-4682	234	5	lead	lead	VERB
fnp-4682	234	6	to	to	ADP
fnp-4682	234	7	secondary	secondary	ADJ
fnp-4682	234	8	mitochondrial	mitochondrial	ADJ
fnp-4682	234	9	abnormalities	abnormality	NOUN
fnp-4682	234	10	in	in	ADP
fnp-4682	234	11	other	other	ADJ
fnp-4682	234	12	inflammatory	inflammatory	ADJ
fnp-4682	234	13	myopathies	myopathy	NOUN
fnp-4682	234	14	(	(	PUNCT
fnp-4682	234	15	hedberg	hedberg	PROPN
fnp-4682	234	16	-	-	PUNCT
fnp-4682	234	17	oldfors	oldfor	NOUN
fnp-4682	234	18	et	et	PROPN
fnp-4682	234	19	al	al	PROPN
fnp-4682	234	20	.	.	PROPN
fnp-4682	234	21	,	,	PUNCT
fnp-4682	234	22	2022	2022	NUM
fnp-4682	234	23	)	)	PUNCT
fnp-4682	234	24	,	,	PUNCT
fnp-4682	234	25	it	it	PRON
fnp-4682	234	26	is	be	AUX
fnp-4682	234	27	possible	possible	ADJ
fnp-4682	234	28	that	that	SCONJ
fnp-4682	234	29	emergence	emergence	NOUN
fnp-4682	234	30	of	of	ADP
fnp-4682	234	31	cox	cox	PROPN
fnp-4682	234	32	-	-	PUNCT
fnp-4682	234	33	negative	negative	ADJ
fnp-4682	234	34	fibers	fiber	NOUN
fnp-4682	234	35	in	in	ADP
fnp-4682	234	36	pm	pm	PROPN
fnp-4682	234	37	-	-	PUNCT
fnp-4682	234	38	mito	mito	PROPN
fnp-4682	234	39	represents	represent	VERB
fnp-4682	234	40	the	the	DET
fnp-4682	234	41	first	first	ADJ
fnp-4682	234	42	step	step	NOUN
fnp-4682	234	43	on	on	ADP
fnp-4682	234	44	the	the	DET
fnp-4682	234	45	pathway	pathway	NOUN
fnp-4682	234	46	towards	towards	ADP
fnp-4682	234	47	treatment	treatment	NOUN
fnp-4682	234	48	resistance	resistance	NOUN
fnp-4682	234	49	in	in	ADP
fnp-4682	234	50	the	the	DET
fnp-4682	234	51	setting	setting	NOUN
fnp-4682	234	52	of	of	ADP
fnp-4682	234	53	persistent	persistent	ADJ
fnp-4682	234	54	chronic	chronic	ADJ
fnp-4682	234	55	inflammation	inflammation	NOUN
fnp-4682	234	56	.	.	PUNCT
fnp-4682	235	1	advances	advance	NOUN
fnp-4682	235	2	in	in	ADP
fnp-4682	235	3	neuromuscular	neuromuscular	ADJ
fnp-4682	235	4	disease	disease	NOUN
fnp-4682	235	5	diagnostics	diagnostic	NOUN
fnp-4682	235	6	8	8	NUM
fnp-4682	235	7	.	.	PUNCT
fnp-4682	235	8	improved	improve	VERB
fnp-4682	235	9	genetic	genetic	ADJ
fnp-4682	235	10	testing	testing	NOUN
fnp-4682	235	11	techniques	technique	NOUN
fnp-4682	235	12	for	for	ADP
fnp-4682	235	13	facioscapulohumeral	facioscapulohumeral	ADJ
fnp-4682	235	14	and	and	CCONJ
fnp-4682	235	15	myotonic	myotonic	ADJ
fnp-4682	235	16	muscular	muscular	ADJ
fnp-4682	235	17	dystrophies	dystrophy	NOUN
fnp-4682	235	18	despite	despite	SCONJ
fnp-4682	235	19	widespread	widespread	ADJ
fnp-4682	235	20	availability	availability	NOUN
fnp-4682	235	21	and	and	CCONJ
fnp-4682	235	22	relatively	relatively	ADV
fnp-4682	235	23	low	low	ADJ
fnp-4682	235	24	cost	cost	NOUN
fnp-4682	235	25	of	of	ADP
fnp-4682	235	26	advanced	advanced	ADJ
fnp-4682	235	27	genetic	genetic	ADJ
fnp-4682	235	28	testing	testing	NOUN
fnp-4682	235	29	techniques	technique	NOUN
fnp-4682	235	30	(	(	PUNCT
fnp-4682	235	31	such	such	ADJ
fnp-4682	235	32	as	as	ADP
fnp-4682	235	33	syndrome	syndrome	NOUN
fnp-4682	235	34	-	-	PUNCT
fnp-4682	235	35	specific	specific	ADJ
fnp-4682	235	36	multigene	multigene	NOUN
fnp-4682	235	37	panels	panel	NOUN
fnp-4682	235	38	and	and	CCONJ
fnp-4682	235	39	whole	whole	ADJ
fnp-4682	235	40	exome	exome	NOUN
fnp-4682	235	41	sequencing	sequencing	NOUN
fnp-4682	235	42	)	)	PUNCT
fnp-4682	235	43	,	,	PUNCT
fnp-4682	235	44	50	50	NUM
fnp-4682	235	45	-	-	SYM
fnp-4682	235	46	75	75	NUM
fnp-4682	235	47	%	%	NOUN
fnp-4682	235	48	of	of	ADP
fnp-4682	235	49	presumed	presume	VERB
fnp-4682	235	50	genetic	genetic	ADJ
fnp-4682	235	51	neuromuscular	neuromuscular	ADJ
fnp-4682	235	52	disease	disease	NOUN
fnp-4682	235	53	cases	case	NOUN
fnp-4682	235	54	currently	currently	ADV
fnp-4682	235	55	remain	remain	VERB
fnp-4682	235	56	undiagnosed	undiagnosed	ADJ
fnp-4682	235	57	(	(	PUNCT
fnp-4682	235	58	cummings	cummings	PROPN
fnp-4682	235	59	et	et	PROPN
fnp-4682	235	60	al	al	PROPN
fnp-4682	235	61	.	.	PROPN
fnp-4682	235	62	,	,	PUNCT
fnp-4682	235	63	2017	2017	NUM
fnp-4682	235	64	)	)	PUNCT
fnp-4682	235	65	.	.	PUNCT
fnp-4682	236	1	the	the	DET
fnp-4682	236	2	underlying	underlie	VERB
fnp-4682	236	3	reasons	reason	NOUN
fnp-4682	236	4	for	for	ADP
fnp-4682	236	5	these	these	DET
fnp-4682	236	6	diagnostic	diagnostic	ADJ
fnp-4682	236	7	challenges	challenge	NOUN
fnp-4682	236	8	are	be	AUX
fnp-4682	236	9	complex	complex	ADJ
fnp-4682	236	10	and	and	CCONJ
fnp-4682	236	11	varied	varied	ADJ
fnp-4682	236	12	,	,	PUNCT
fnp-4682	236	13	but	but	CCONJ
fnp-4682	236	14	include	include	VERB
fnp-4682	236	15	the	the	DET
fnp-4682	236	16	inability	inability	NOUN
fnp-4682	236	17	of	of	ADP
fnp-4682	236	18	these	these	DET
fnp-4682	236	19	sequencing	sequence	VERB
fnp-4682	236	20	techniques	technique	NOUN
fnp-4682	236	21	to	to	PART
fnp-4682	236	22	detect	detect	VERB
fnp-4682	236	23	structural	structural	ADJ
fnp-4682	236	24	rearrangements	rearrangement	NOUN
fnp-4682	236	25	and	and	CCONJ
fnp-4682	236	26	copy	copy	VERB
fnp-4682	236	27	number	number	NOUN
fnp-4682	236	28	variants	variant	NOUN
fnp-4682	236	29	.	.	PUNCT
fnp-4682	237	1	fortunately	fortunately	ADV
fnp-4682	237	2	,	,	PUNCT
fnp-4682	237	3	two	two	NUM
fnp-4682	237	4	new	new	ADJ
fnp-4682	237	5	genetic	genetic	ADJ
fnp-4682	237	6	testing	testing	NOUN
fnp-4682	237	7	strategies	strategy	NOUN
fnp-4682	237	8	developed	develop	VERB
fnp-4682	237	9	in	in	ADP
fnp-4682	237	10	2022	2022	NUM
fnp-4682	237	11	will	will	AUX
fnp-4682	237	12	alleviate	alleviate	VERB
fnp-4682	237	13	some	some	PRON
fnp-4682	237	14	of	of	ADP
fnp-4682	237	15	these	these	DET
fnp-4682	237	16	challenges	challenge	NOUN
fnp-4682	237	17	,	,	PUNCT
fnp-4682	237	18	simplifying	simplify	VERB
fnp-4682	237	19	the	the	DET
fnp-4682	237	20	diagnosis	diagnosis	NOUN
fnp-4682	237	21	of	of	ADP
fnp-4682	237	22	two	two	NUM
fnp-4682	237	23	common	common	ADJ
fnp-4682	237	24	muscular	muscular	ADJ
fnp-4682	237	25	dystrophies	dystrophy	NOUN
fnp-4682	237	26	(	(	PUNCT
fnp-4682	237	27	erdmann	erdmann	PROPN
fnp-4682	237	28	et	et	PROPN
fnp-4682	237	29	al	al	PROPN
fnp-4682	237	30	.	.	PROPN
fnp-4682	237	31	,	,	PUNCT
fnp-4682	237	32	2022	2022	NUM
fnp-4682	237	33	;	;	PUNCT
fnp-4682	237	34	stevanovski	stevanovski	PRON
fnp-4682	237	35	et	et	PROPN
fnp-4682	237	36	al	al	PROPN
fnp-4682	237	37	.	.	PROPN
fnp-4682	237	38	,	,	PUNCT
fnp-4682	237	39	2022	2022	NUM
fnp-4682	237	40	)	)	PUNCT
fnp-4682	237	41	.	.	PUNCT
fnp-4682	238	1	facioscapulohumeral	facioscapulohumeral	ADJ
fnp-4682	238	2	muscular	muscular	ADJ
fnp-4682	238	3	dystrophy	dystrophy	NOUN
fnp-4682	238	4	(	(	PUNCT
fnp-4682	238	5	fshd	fshd	ADJ
fnp-4682	238	6	)	)	PUNCT
fnp-4682	238	7	is	be	AUX
fnp-4682	238	8	the	the	DET
fnp-4682	238	9	third	third	ADJ
fnp-4682	238	10	most	most	ADV
fnp-4682	238	11	common	common	ADJ
fnp-4682	238	12	muscular	muscular	ADJ
fnp-4682	238	13	dystrophy	dystrophy	NOUN
fnp-4682	238	14	;	;	PUNCT
fnp-4682	238	15	it	it	PRON
fnp-4682	238	16	has	have	VERB
fnp-4682	238	17	a	a	DET
fnp-4682	238	18	fairly	fairly	ADV
fnp-4682	238	19	unique	unique	ADJ
fnp-4682	238	20	clinical	clinical	ADJ
fnp-4682	238	21	presentation	presentation	NOUN
fnp-4682	238	22	,	,	PUNCT
fnp-4682	238	23	with	with	ADP
fnp-4682	238	24	the	the	DET
fnp-4682	238	25	facial	facial	ADJ
fnp-4682	238	26	and	and	CCONJ
fnp-4682	238	27	shoulder	shoulder	NOUN
fnp-4682	238	28	girdle	girdle	NOUN
fnp-4682	238	29	weakness	weakness	NOUN
fnp-4682	238	30	that	that	PRON
fnp-4682	238	31	progresses	progress	VERB
fnp-4682	238	32	to	to	PART
fnp-4682	238	33	involve	involve	VERB
fnp-4682	238	34	distal	distal	ADJ
fnp-4682	238	35	legs	leg	NOUN
fnp-4682	238	36	and	and	CCONJ
fnp-4682	238	37	the	the	DET
fnp-4682	238	38	pelvic	pelvic	ADJ
fnp-4682	238	39	girdle	girdle	NOUN
fnp-4682	238	40	.	.	PUNCT
fnp-4682	239	1	however	however	ADV
fnp-4682	239	2	,	,	PUNCT
fnp-4682	239	3	the	the	DET
fnp-4682	239	4	age	age	NOUN
fnp-4682	239	5	of	of	ADP
fnp-4682	239	6	onset	onset	NOUN
fnp-4682	239	7	is	be	AUX
fnp-4682	239	8	highly	highly	ADV
fnp-4682	239	9	variable	variable	ADJ
fnp-4682	239	10	(	(	PUNCT
fnp-4682	239	11	from	from	ADP
fnp-4682	239	12	infancy	infancy	NOUN
fnp-4682	239	13	to	to	ADP
fnp-4682	239	14	late	late	ADJ
fnp-4682	239	15	adulthood	adulthood	NOUN
fnp-4682	239	16	)	)	PUNCT
fnp-4682	239	17	and	and	CCONJ
fnp-4682	239	18	the	the	DET
fnp-4682	239	19	phenotype	phenotype	NOUN
fnp-4682	239	20	can	can	AUX
fnp-4682	239	21	also	also	ADV
fnp-4682	239	22	vary	vary	VERB
fnp-4682	239	23	,	,	PUNCT
fnp-4682	239	24	making	make	VERB
fnp-4682	239	25	the	the	DET
fnp-4682	239	26	diagnosis	diagnosis	NOUN
fnp-4682	239	27	challenging	challenging	ADJ
fnp-4682	239	28	.	.	PUNCT
fnp-4682	240	1	histopathologic	histopathologic	PROPN
fnp-4682	240	2	features	feature	NOUN
fnp-4682	240	3	of	of	ADP
fnp-4682	240	4	fshd	fshd	ADJ
fnp-4682	240	5	are	be	AUX
fnp-4682	240	6	relatively	relatively	ADV
fnp-4682	240	7	unique	unique	ADJ
fnp-4682	240	8	(	(	PUNCT
fnp-4682	240	9	fig	fig	NOUN
fnp-4682	240	10	.	.	PUNCT
fnp-4682	241	1	6	6	NUM
fnp-4682	241	2	)	)	PUNCT
fnp-4682	241	3	,	,	PUNCT
fnp-4682	241	4	but	but	CCONJ
fnp-4682	241	5	not	not	PART
fnp-4682	241	6	sufficiently	sufficiently	ADV
fnp-4682	241	7	specific	specific	ADJ
fnp-4682	241	8	to	to	PART
fnp-4682	241	9	enable	enable	VERB
fnp-4682	241	10	definitive	definitive	ADJ
fnp-4682	241	11	diagnosis	diagnosis	NOUN
fnp-4682	241	12	;	;	PUNCT
fnp-4682	241	13	hence	hence	ADV
fnp-4682	241	14	,	,	PUNCT
fnp-4682	241	15	directed	direct	VERB
fnp-4682	241	16	genetic	genetic	ADJ
fnp-4682	241	17	testing	testing	NOUN
fnp-4682	241	18	is	be	AUX
fnp-4682	241	19	generally	generally	ADV
fnp-4682	241	20	required	require	VERB
fnp-4682	241	21	at	at	ADP
fnp-4682	241	22	some	some	DET
fnp-4682	241	23	point	point	NOUN
fnp-4682	241	24	of	of	ADP
fnp-4682	241	25	diagnostic	diagnostic	ADJ
fnp-4682	241	26	work	work	NOUN
fnp-4682	241	27	-	-	PUNCT
fnp-4682	241	28	up	up	NOUN
fnp-4682	241	29	.	.	PUNCT
fnp-4682	242	1	molecularly	molecularly	ADV
fnp-4682	242	2	,	,	PUNCT
fnp-4682	242	3	fshd	fshd	ADV
fnp-4682	242	4	is	be	AUX
fnp-4682	242	5	caused	cause	VERB
fnp-4682	242	6	by	by	ADP
fnp-4682	242	7	aberrant	aberrant	ADJ
fnp-4682	242	8	expression	expression	NOUN
fnp-4682	242	9	of	of	ADP
fnp-4682	242	10	dux4	dux4	NOUN
fnp-4682	242	11	(	(	PUNCT
fnp-4682	242	12	double	double	ADJ
fnp-4682	242	13	homeobox	homeobox	NOUN
fnp-4682	242	14	4	4	NUM
fnp-4682	242	15	)	)	PUNCT
fnp-4682	242	16	protein	protein	NOUN
fnp-4682	242	17	in	in	ADP
fnp-4682	242	18	skeletal	skeletal	ADJ
fnp-4682	242	19	muscle	muscle	NOUN
fnp-4682	242	20	,	,	PUNCT
fnp-4682	242	21	which	which	PRON
fnp-4682	242	22	has	have	VERB
fnp-4682	242	23	myotoxic	myotoxic	ADJ
fnp-4682	242	24	effects	effect	NOUN
fnp-4682	242	25	.	.	PUNCT
fnp-4682	243	1	dux4	dux4	PROPN
fnp-4682	243	2	is	be	AUX
fnp-4682	243	3	a	a	DET
fnp-4682	243	4	transcription	transcription	NOUN
fnp-4682	243	5	factor	factor	NOUN
fnp-4682	243	6	that	that	PRON
fnp-4682	243	7	regulates	regulate	VERB
fnp-4682	243	8	expression	expression	NOUN
fnp-4682	243	9	of	of	ADP
fnp-4682	243	10	genes	gene	NOUN
fnp-4682	243	11	important	important	ADJ
fnp-4682	243	12	for	for	ADP
fnp-4682	243	13	preand	preand	VERB
fnp-4682	243	14	post	post	ADJ
fnp-4682	243	15	-	-	ADJ
fnp-4682	243	16	implantation	implantation	ADJ
fnp-4682	243	17	development	development	NOUN
fnp-4682	243	18	,	,	PUNCT
fnp-4682	243	19	but	but	CCONJ
fnp-4682	243	20	is	be	AUX
fnp-4682	243	21	epigenetically	epigenetically	ADV
fnp-4682	243	22	silenced	silence	VERB
fnp-4682	243	23	in	in	ADP
fnp-4682	243	24	most	most	ADJ
fnp-4682	243	25	adult	adult	NOUN
fnp-4682	243	26	tissues	tissue	NOUN
fnp-4682	243	27	except	except	SCONJ
fnp-4682	243	28	in	in	ADP
fnp-4682	243	29	thymus	thymus	NOUN
fnp-4682	243	30	and	and	CCONJ
fnp-4682	243	31	testis	testis	NOUN
fnp-4682	243	32	,	,	PUNCT
fnp-4682	243	33	where	where	SCONJ
fnp-4682	243	34	it	it	PRON
fnp-4682	243	35	has	have	VERB
fnp-4682	243	36	an	an	DET
fnp-4682	243	37	unknown	unknown	ADJ
fnp-4682	243	38	function	function	NOUN
fnp-4682	243	39	(	(	PUNCT
fnp-4682	243	40	mocciaro	mocciaro	NOUN
fnp-4682	243	41	et	et	PROPN
fnp-4682	243	42	al	al	PROPN
fnp-4682	243	43	.	.	PROPN
fnp-4682	243	44	,	,	PUNCT
fnp-4682	243	45	2021	2021	NUM
fnp-4682	243	46	)	)	PUNCT
fnp-4682	243	47	.	.	PUNCT
fnp-4682	244	1	in	in	ADP
fnp-4682	244	2	fshd	fshd	ADJ
fnp-4682	244	3	,	,	PUNCT
fnp-4682	244	4	there	there	PRON
fnp-4682	244	5	is	be	VERB
fnp-4682	244	6	a	a	DET
fnp-4682	244	7	loss	loss	NOUN
fnp-4682	244	8	of	of	ADP
fnp-4682	244	9	dux4	dux4	NOUN
fnp-4682	244	10	repression	repression	NOUN
fnp-4682	244	11	,	,	PUNCT
fnp-4682	244	12	but	but	CCONJ
fnp-4682	244	13	that	that	DET
fnp-4682	244	14	derepression	derepression	NOUN
fnp-4682	244	15	occurs	occur	VERB
fnp-4682	244	16	through	through	ADP
fnp-4682	244	17	mechanisms	mechanism	NOUN
fnp-4682	244	18	that	that	PRON
fnp-4682	244	19	differ	differ	VERB
fnp-4682	244	20	between	between	ADP
fnp-4682	244	21	two	two	NUM
fnp-4682	244	22	disease	disease	NOUN
fnp-4682	244	23	subtypes	subtype	NOUN
fnp-4682	244	24	,	,	PUNCT
fnp-4682	244	25	fshd1	fshd1	NOUN
fnp-4682	244	26	and	and	CCONJ
fnp-4682	244	27	fshd2	fshd2	PROPN
fnp-4682	244	28	.	.	PUNCT
fnp-4682	245	1	in	in	ADP
fnp-4682	245	2	fshd1	fshd1	NOUN
fnp-4682	245	3	(	(	PUNCT
fnp-4682	245	4	~95	~95	X
fnp-4682	245	5	%	%	NOUN
fnp-4682	245	6	of	of	ADP
fnp-4682	245	7	cases	case	NOUN
fnp-4682	245	8	)	)	PUNCT
fnp-4682	245	9	,	,	PUNCT
fnp-4682	245	10	dux4	dux4	NOUN
fnp-4682	245	11	derepression	derepression	NOUN
fnp-4682	245	12	is	be	AUX
fnp-4682	245	13	caused	cause	VERB
fnp-4682	245	14	by	by	ADP
fnp-4682	245	15	contraction	contraction	NOUN
fnp-4682	245	16	of	of	ADP
fnp-4682	245	17	the	the	DET
fnp-4682	245	18	d4z4	d4z4	PROPN
fnp-4682	245	19	macrosatellite	macrosatellite	PROPN
fnp-4682	245	20	repeat	repeat	NOUN
fnp-4682	245	21	array	array	NOUN
fnp-4682	245	22	in	in	ADP
fnp-4682	245	23	the	the	DET
fnp-4682	245	24	subtelomeric	subtelomeric	ADJ
fnp-4682	245	25	region	region	NOUN
fnp-4682	245	26	of	of	ADP
fnp-4682	245	27	chromosome	chromosome	NOUN
fnp-4682	245	28	4q35	4q35	NUM
fnp-4682	245	29	to	to	ADP
fnp-4682	245	30	<	<	X
fnp-4682	245	31	12	12	NUM
fnp-4682	245	32	repeating	repeat	VERB
fnp-4682	245	33	units	unit	NOUN
fnp-4682	245	34	;	;	PUNCT
fnp-4682	245	35	in	in	ADP
fnp-4682	245	36	fshd2	fshd2	NOUN
fnp-4682	245	37	(	(	PUNCT
fnp-4682	245	38	~5	~5	NUM
fnp-4682	245	39	%	%	NOUN
fnp-4682	245	40	of	of	ADP
fnp-4682	245	41	cases	case	NOUN
fnp-4682	245	42	)	)	PUNCT
fnp-4682	245	43	,	,	PUNCT
fnp-4682	245	44	there	there	PRON
fnp-4682	245	45	is	be	VERB
fnp-4682	245	46	global	global	ADJ
fnp-4682	245	47	hypomethylation	hypomethylation	NOUN
fnp-4682	245	48	of	of	ADP
fnp-4682	245	49	the	the	DET
fnp-4682	245	50	d4z4	d4z4	X
fnp-4682	245	51	array	array	NOUN
fnp-4682	245	52	due	due	ADP
fnp-4682	245	53	to	to	ADP
fnp-4682	245	54	mutations	mutation	NOUN
fnp-4682	245	55	in	in	ADP
fnp-4682	245	56	one	one	NUM
fnp-4682	245	57	of	of	ADP
fnp-4682	245	58	the	the	DET
fnp-4682	245	59	several	several	ADJ
fnp-4682	245	60	genes	gene	NOUN
fnp-4682	245	61	that	that	PRON
fnp-4682	245	62	encode	encode	ADJ
fnp-4682	245	63	proteins	protein	NOUN
fnp-4682	245	64	required	require	VERB
fnp-4682	245	65	for	for	ADP
fnp-4682	245	66	epigenetic	epigenetic	ADJ
fnp-4682	245	67	suppression	suppression	NOUN
fnp-4682	245	68	.	.	PUNCT
fnp-4682	246	1	(	(	PUNCT
fnp-4682	246	2	a	a	DET
fnp-4682	246	3	permissive	permissive	ADJ
fnp-4682	246	4	haplotype	haplotype	NOUN
fnp-4682	246	5	4qa	4qa	NOUN
fnp-4682	246	6	or	or	CCONJ
fnp-4682	246	7	4qal	4qal	NUM
fnp-4682	246	8	,	,	PUNCT
fnp-4682	246	9	which	which	PRON
fnp-4682	246	10	provides	provide	VERB
fnp-4682	246	11	a	a	DET
fnp-4682	246	12	polya	polya	NOUN
fnp-4682	246	13	signal	signal	NOUN
fnp-4682	246	14	for	for	ADP
fnp-4682	246	15	dux4	dux4	PROPN
fnp-4682	246	16	mrna	mrna	PROPN
fnp-4682	246	17	,	,	PUNCT
fnp-4682	246	18	is	be	AUX
fnp-4682	246	19	required	require	VERB
fnp-4682	246	20	for	for	ADP
fnp-4682	246	21	phenotypic	phenotypic	ADJ
fnp-4682	246	22	disease	disease	NOUN
fnp-4682	246	23	expression	expression	NOUN
fnp-4682	246	24	in	in	ADP
fnp-4682	246	25	either	either	DET
fnp-4682	246	26	disease	disease	NOUN
fnp-4682	246	27	subtype	subtype	NOUN
fnp-4682	246	28	.	.	PUNCT
fnp-4682	246	29	)	)	PUNCT
fnp-4682	247	1	currently	currently	ADV
fnp-4682	247	2	,	,	PUNCT
fnp-4682	247	3	genetic	genetic	ADJ
fnp-4682	247	4	diagnosis	diagnosis	NOUN
fnp-4682	247	5	of	of	ADP
fnp-4682	247	6	fshd	fshd	ADJ
fnp-4682	247	7	requires	require	NOUN
fnp-4682	247	8	(	(	PUNCT
fnp-4682	247	9	i	i	NOUN
fnp-4682	247	10	)	)	PUNCT
fnp-4682	247	11	confirmation	confirmation	NOUN
fnp-4682	247	12	of	of	ADP
fnp-4682	247	13	the	the	DET
fnp-4682	247	14	permissive	permissive	ADJ
fnp-4682	247	15	haplotype	haplotype	NOUN
fnp-4682	247	16	,	,	PUNCT
fnp-4682	247	17	(	(	PUNCT
fnp-4682	247	18	ii	ii	NOUN
fnp-4682	247	19	)	)	PUNCT
fnp-4682	247	20	determination	determination	NOUN
fnp-4682	247	21	of	of	ADP
fnp-4682	247	22	the	the	DET
fnp-4682	247	23	d4z4	d4z4	PUNCT
fnp-4682	247	24	repeat	repeat	NOUN
fnp-4682	247	25	length	length	NOUN
fnp-4682	247	26	,	,	PUNCT
fnp-4682	247	27	typically	typically	ADV
fnp-4682	247	28	via	via	ADP
fnp-4682	247	29	southern	southern	ADJ
fnp-4682	247	30	blotting	blotting	NOUN
fnp-4682	247	31	(	(	PUNCT
fnp-4682	247	32	which	which	PRON
fnp-4682	247	33	requires	require	VERB
fnp-4682	247	34	a	a	DET
fnp-4682	247	35	large	large	ADJ
fnp-4682	247	36	amount	amount	NOUN
fnp-4682	247	37	of	of	ADP
fnp-4682	247	38	high	high	ADJ
fnp-4682	247	39	molecular	molecular	ADJ
fnp-4682	247	40	weight	weight	NOUN
fnp-4682	247	41	dna	dna	NOUN
fnp-4682	247	42	)	)	PUNCT
fnp-4682	247	43	,	,	PUNCT
fnp-4682	247	44	and	and	CCONJ
fnp-4682	247	45	(	(	PUNCT
fnp-4682	247	46	iii	iii	NOUN
fnp-4682	247	47	)	)	PUNCT
fnp-4682	247	48	sequencing	sequencing	NOUN
fnp-4682	247	49	of	of	ADP
fnp-4682	247	50	epigenetic	epigenetic	ADJ
fnp-4682	247	51	suppressor	suppressor	NOUN
fnp-4682	247	52	genes	gene	NOUN
fnp-4682	247	53	if	if	SCONJ
fnp-4682	247	54	the	the	DET
fnp-4682	247	55	d4z4	d4z4	PUNCT
fnp-4682	247	56	repeat	repeat	NOUN
fnp-4682	247	57	length	length	NOUN
fnp-4682	247	58	is	be	AUX
fnp-4682	247	59	found	find	VERB
fnp-4682	247	60	to	to	PART
fnp-4682	247	61	be	be	AUX
fnp-4682	247	62	within	within	ADP
fnp-4682	247	63	normal	normal	ADJ
fnp-4682	247	64	limits	limit	NOUN
fnp-4682	247	65	.	.	PUNCT
fnp-4682	248	1	the	the	DET
fnp-4682	248	2	new	new	ADJ
fnp-4682	248	3	,	,	PUNCT
fnp-4682	248	4	much	much	ADV
fnp-4682	248	5	more	more	ADV
fnp-4682	248	6	streamlined	streamlined	ADJ
fnp-4682	248	7	approach	approach	NOUN
fnp-4682	248	8	for	for	ADP
fnp-4682	248	9	fshd	fshd	ADJ
fnp-4682	248	10	testing	testing	NOUN
fnp-4682	248	11	developed	develop	VERB
fnp-4682	248	12	by	by	ADP
fnp-4682	248	13	erdmann	erdmann	PROPN
fnp-4682	248	14	et	et	PROPN
fnp-4682	248	15	al	al	PROPN
fnp-4682	248	16	.	.	PROPN
fnp-4682	248	17	is	be	AUX
fnp-4682	248	18	based	base	VERB
fnp-4682	248	19	on	on	ADP
fnp-4682	248	20	methylation	methylation	NOUN
fnp-4682	248	21	profiling	profiling	NOUN
fnp-4682	248	22	:	:	PUNCT
fnp-4682	248	23	following	follow	VERB
fnp-4682	248	24	confirmation	confirmation	NOUN
fnp-4682	248	25	of	of	ADP
fnp-4682	248	26	the	the	DET
fnp-4682	248	27	permissive	permissive	ADJ
fnp-4682	248	28	haplotype	haplotype	NOUN
fnp-4682	248	29	,	,	PUNCT
fnp-4682	248	30	a	a	DET
fnp-4682	248	31	high	high	ADJ
fnp-4682	248	32	-	-	PUNCT
fnp-4682	248	33	throughput	throughput	NOUN
fnp-4682	248	34	methylation	methylation	NOUN
fnp-4682	248	35	profile	profile	NOUN
fnp-4682	248	36	analysis	analysis	NOUN
fnp-4682	248	37	is	be	AUX
fnp-4682	248	38	used	use	VERB
fnp-4682	248	39	to	to	PART
fnp-4682	248	40	determine	determine	VERB
fnp-4682	248	41	the	the	DET
fnp-4682	248	42	global	global	ADJ
fnp-4682	248	43	methylation	methylation	NOUN
fnp-4682	248	44	level	level	NOUN
fnp-4682	248	45	of	of	ADP
fnp-4682	248	46	the	the	DET
fnp-4682	248	47	entire	entire	ADJ
fnp-4682	248	48	d4z4	d4z4	PUNCT
fnp-4682	248	49	repeat	repeat	NOUN
fnp-4682	248	50	array	array	NOUN
fnp-4682	248	51	as	as	ADV
fnp-4682	248	52	well	well	ADV
fnp-4682	248	53	as	as	ADP
fnp-4682	248	54	the	the	DET
fnp-4682	248	55	regional	regional	ADJ
fnp-4682	248	56	methylation	methylation	NOUN
fnp-4682	248	57	of	of	ADP
fnp-4682	248	58	its	its	PRON
fnp-4682	248	59	most	most	ADV
fnp-4682	248	60	distal	distal	ADJ
fnp-4682	248	61	repeat	repeat	NOUN
fnp-4682	248	62	unit	unit	NOUN
fnp-4682	248	63	;	;	PUNCT
fnp-4682	248	64	individuals	individual	NOUN
fnp-4682	248	65	with	with	ADP
fnp-4682	248	66	isolated	isolated	ADJ
fnp-4682	248	67	distal	distal	ADJ
fnp-4682	248	68	hypomethylation	hypomethylation	NOUN
fnp-4682	248	69	have	have	VERB
fnp-4682	248	70	fshd1	fshd1	NOUN
fnp-4682	248	71	,	,	PUNCT
fnp-4682	248	72	while	while	SCONJ
fnp-4682	248	73	individuals	individual	NOUN
fnp-4682	248	74	with	with	ADP
fnp-4682	248	75	both	both	CCONJ
fnp-4682	248	76	global	global	ADJ
fnp-4682	248	77	and	and	CCONJ
fnp-4682	248	78	distal	distal	ADJ
fnp-4682	248	79	hypomethylation	hypomethylation	NOUN
fnp-4682	248	80	have	have	VERB
fnp-4682	248	81	fshd2	fshd2	X
fnp-4682	248	82	(	(	PUNCT
fnp-4682	248	83	erdmann	erdmann	VERB
fnp-4682	248	84	et	et	PROPN
fnp-4682	248	85	al	al	PROPN
fnp-4682	248	86	.	.	PROPN
fnp-4682	248	87	,	,	PUNCT
fnp-4682	248	88	2022	2022	NUM
fnp-4682	248	89	)	)	PUNCT
fnp-4682	248	90	.	.	PUNCT
fnp-4682	249	1	not	not	PART
fnp-4682	249	2	only	only	ADV
fnp-4682	249	3	does	do	AUX
fnp-4682	249	4	this	this	DET
fnp-4682	249	5	new	new	ADJ
fnp-4682	249	6	diagnostic	diagnostic	ADJ
fnp-4682	249	7	approach	approach	NOUN
fnp-4682	249	8	require	require	VERB
fnp-4682	249	9	much	much	ADV
fnp-4682	249	10	smaller	small	ADJ
fnp-4682	249	11	quantity	quantity	NOUN
fnp-4682	249	12	of	of	ADP
fnp-4682	249	13	dna	dna	NOUN
fnp-4682	249	14	and	and	CCONJ
fnp-4682	249	15	less	less	ADJ
fnp-4682	249	16	laboratory	laboratory	NOUN
fnp-4682	249	17	effort	effort	NOUN
fnp-4682	249	18	,	,	PUNCT
fnp-4682	249	19	it	it	PRON
fnp-4682	249	20	also	also	ADV
fnp-4682	249	21	detects	detect	VERB
fnp-4682	249	22	cases	case	NOUN
fnp-4682	249	23	that	that	PRON
fnp-4682	249	24	are	be	AUX
fnp-4682	249	25	missed	miss	VERB
fnp-4682	249	26	with	with	ADP
fnp-4682	249	27	traditional	traditional	ADJ
fnp-4682	249	28	methods	method	NOUN
fnp-4682	249	29	(	(	PUNCT
fnp-4682	249	30	for	for	ADP
fnp-4682	249	31	example	example	NOUN
fnp-4682	249	32	,	,	PUNCT
fnp-4682	249	33	patients	patient	NOUN
fnp-4682	249	34	with	with	ADP
fnp-4682	249	35	complex	complex	ADJ
fnp-4682	249	36	chromosomal	chromosomal	ADJ
fnp-4682	249	37	rearrangements	rearrangement	NOUN
fnp-4682	249	38	that	that	PRON
fnp-4682	249	39	can	can	AUX
fnp-4682	249	40	not	not	PART
fnp-4682	249	41	be	be	AUX
fnp-4682	249	42	detected	detect	VERB
fnp-4682	249	43	by	by	ADP
fnp-4682	249	44	southern	southern	ADJ
fnp-4682	249	45	blotting	blotting	NOUN
fnp-4682	249	46	)	)	PUNCT
fnp-4682	249	47	or	or	CCONJ
fnp-4682	249	48	cases	case	NOUN
fnp-4682	249	49	that	that	PRON
fnp-4682	249	50	are	be	AUX
fnp-4682	249	51	in	in	ADP
fnp-4682	249	52	the	the	DET
fnp-4682	249	53	gray	gray	ADJ
fnp-4682	249	54	zone	zone	NOUN
fnp-4682	249	55	between	between	ADP
fnp-4682	249	56	fshd1	fshd1	NOUN
fnp-4682	249	57	and	and	CCONJ
fnp-4682	249	58	fshd2	fshd2	PROPN
fnp-4682	249	59	(	(	PUNCT
fnp-4682	249	60	which	which	PRON
fnp-4682	249	61	represent	represent	VERB
fnp-4682	249	62	the	the	DET
fnp-4682	249	63	two	two	NUM
fnp-4682	249	64	ends	end	NOUN
fnp-4682	249	65	of	of	ADP
fnp-4682	249	66	the	the	DET
fnp-4682	249	67	epigenetic	epigenetic	ADJ
fnp-4682	249	68	disease	disease	NOUN
fnp-4682	249	69	continuum	continuum	VERB
fnp-4682	249	70	)	)	PUNCT
fnp-4682	249	71	.	.	PUNCT
fnp-4682	250	1	in	in	ADP
fnp-4682	250	2	addition	addition	NOUN
fnp-4682	250	3	,	,	PUNCT
fnp-4682	250	4	erdmann	erdmann	PROPN
fnp-4682	250	5	et	et	PROPN
fnp-4682	250	6	al	al	PROPN
fnp-4682	250	7	.	.	PROPN
fnp-4682	250	8	have	have	AUX
fnp-4682	250	9	shown	show	VERB
fnp-4682	250	10	that	that	SCONJ
fnp-4682	250	11	the	the	DET
fnp-4682	250	12	d4z4	d4z4	PUNCT
fnp-4682	250	13	repeat	repeat	PROPN
fnp-4682	250	14	methylation	methylation	NOUN
fnp-4682	250	15	profile	profile	NOUN
fnp-4682	250	16	is	be	AUX
fnp-4682	250	17	a	a	DET
fnp-4682	250	18	biomarker	biomarker	NOUN
fnp-4682	250	19	of	of	ADP
fnp-4682	250	20	fshd	fshd	ADJ
fnp-4682	250	21	severity	severity	NOUN
fnp-4682	250	22	:	:	PUNCT
fnp-4682	250	23	in	in	ADP
fnp-4682	250	24	their	their	PRON
fnp-4682	250	25	cohort	cohort	NOUN
fnp-4682	250	26	of	of	ADP
fnp-4682	250	27	148	148	NUM
fnp-4682	250	28	patients	patient	NOUN
fnp-4682	250	29	,	,	PUNCT
fnp-4682	250	30	the	the	DET
fnp-4682	250	31	distal	distal	ADJ
fnp-4682	250	32	methylation	methylation	NOUN
fnp-4682	250	33	level	level	NOUN
fnp-4682	250	34	was	be	AUX
fnp-4682	250	35	better	well	ADV
fnp-4682	250	36	correlated	correlate	VERB
fnp-4682	250	37	with	with	ADP
fnp-4682	250	38	clinical	clinical	ADJ
fnp-4682	250	39	findings	finding	NOUN
fnp-4682	250	40	(	(	PUNCT
fnp-4682	250	41	including	include	VERB
fnp-4682	250	42	the	the	DET
fnp-4682	250	43	age	age	NOUN
fnp-4682	250	44	of	of	ADP
fnp-4682	250	45	onset	onset	NOUN
fnp-4682	250	46	)	)	PUNCT
fnp-4682	250	47	than	than	ADP
fnp-4682	250	48	the	the	DET
fnp-4682	250	49	d4z4	d4z4	PUNCT
fnp-4682	250	50	repeat	repeat	NOUN
fnp-4682	250	51	length	length	NOUN
fnp-4682	250	52	.	.	PUNCT
fnp-4682	251	1	finally	finally	ADV
fnp-4682	251	2	,	,	PUNCT
fnp-4682	251	3	this	this	DET
fnp-4682	251	4	study	study	NOUN
fnp-4682	251	5	provides	provide	VERB
fnp-4682	251	6	definitive	definitive	ADJ
fnp-4682	251	7	evidence	evidence	NOUN
fnp-4682	251	8	that	that	SCONJ
fnp-4682	251	9	fshd	fshd	ADJ
fnp-4682	251	10	pathogenesis	pathogenesis	NOUN
fnp-4682	251	11	is	be	AUX
fnp-4682	251	12	ultimately	ultimately	ADV
fnp-4682	251	13	driven	drive	VERB
fnp-4682	251	14	by	by	ADP
fnp-4682	251	15	epigenetic	epigenetic	ADJ
fnp-4682	251	16	rather	rather	ADV
fnp-4682	251	17	than	than	ADP
fnp-4682	251	18	genetic	genetic	ADJ
fnp-4682	251	19	mechanisms	mechanism	NOUN
fnp-4682	251	20	.	.	PUNCT
fnp-4682	252	1	figure	figure	NOUN
fnp-4682	252	2	6	6	NUM
fnp-4682	252	3	.	.	PUNCT
fnp-4682	253	1	histologic	histologic	PROPN
fnp-4682	253	2	findings	finding	NOUN
fnp-4682	253	3	in	in	ADP
fnp-4682	253	4	facioscapulohumeral	facioscapulohumeral	ADJ
fnp-4682	253	5	dystrophy	dystrophy	NOUN
fnp-4682	253	6	(	(	PUNCT
fnp-4682	253	7	fshd	fshd	ADJ
fnp-4682	253	8	)	)	PUNCT
fnp-4682	253	9	.	.	PUNCT
fnp-4682	254	1	(	(	PUNCT
fnp-4682	254	2	a	a	X
fnp-4682	254	3	)	)	PUNCT
fnp-4682	254	4	a	a	DET
fnp-4682	254	5	representative	representative	ADJ
fnp-4682	254	6	h&e	h&e	NOUN
fnp-4682	254	7	-	-	PUNCT
fnp-4682	254	8	stained	stain	VERB
fnp-4682	254	9	section	section	NOUN
fnp-4682	254	10	shows	show	VERB
fnp-4682	254	11	fiber	fiber	NOUN
fnp-4682	254	12	size	size	NOUN
fnp-4682	254	13	variation	variation	NOUN
fnp-4682	254	14	,	,	PUNCT
fnp-4682	254	15	endomysial	endomysial	ADJ
fnp-4682	254	16	fibrosis	fibrosis	NOUN
fnp-4682	254	17	,	,	PUNCT
fnp-4682	254	18	and	and	CCONJ
fnp-4682	254	19	perimysial	perimysial	ADJ
fnp-4682	254	20	inflammation	inflammation	NOUN
fnp-4682	254	21	that	that	SCONJ
fnp-4682	254	22	focally	focally	ADV
fnp-4682	254	23	extends	extend	VERB
fnp-4682	254	24	into	into	ADP
fnp-4682	254	25	the	the	DET
fnp-4682	254	26	endomysium	endomysium	NOUN
fnp-4682	254	27	.	.	PUNCT
fnp-4682	255	1	(	(	PUNCT
fnp-4682	255	2	b	b	X
fnp-4682	255	3	)	)	PUNCT
fnp-4682	255	4	moderately	moderately	ADV
fnp-4682	255	5	frequent	frequent	ADJ
fnp-4682	255	6	lobulated	lobulate	VERB
fnp-4682	255	7	fibers	fiber	NOUN
fnp-4682	255	8	(	(	PUNCT
fnp-4682	255	9	arrowheads	arrowhead	NOUN
fnp-4682	255	10	)	)	PUNCT
fnp-4682	255	11	are	be	AUX
fnp-4682	255	12	best	well	ADV
fnp-4682	255	13	seen	see	VERB
fnp-4682	255	14	on	on	ADP
fnp-4682	255	15	nadh	nadh	NOUN
fnp-4682	255	16	-	-	PUNCT
fnp-4682	255	17	tr	tr	NOUN
fnp-4682	255	18	histochemistry	histochemistry	NOUN
fnp-4682	255	19	.	.	PUNCT
fnp-4682	256	1	(	(	PUNCT
fnp-4682	256	2	c	c	X
fnp-4682	256	3	)	)	PUNCT
fnp-4682	256	4	mhc	mhc	PROPN
fnp-4682	256	5	-	-	PROPN
fnp-4682	256	6	i	i	PRON
fnp-4682	256	7	is	be	AUX
fnp-4682	256	8	diffusely	diffusely	ADV
fnp-4682	256	9	upregulated	upregulate	VERB
fnp-4682	256	10	in	in	ADP
fnp-4682	256	11	muscle	muscle	NOUN
fnp-4682	256	12	fibers	fiber	NOUN
fnp-4682	256	13	.	.	PUNCT
fnp-4682	257	1	(	(	PUNCT
fnp-4682	257	2	d	d	X
fnp-4682	257	3	)	)	PUNCT
fnp-4682	257	4	cd31	cd31	PROPN
fnp-4682	257	5	immunohistochemistry	immunohistochemistry	NOUN
fnp-4682	257	6	highlights	highlight	NOUN
fnp-4682	257	7	enlarged	enlarge	VERB
fnp-4682	257	8	endomysial	endomysial	ADJ
fnp-4682	257	9	capillaries	capillary	NOUN
fnp-4682	257	10	.	.	PUNCT
fnp-4682	258	1	based	base	VERB
fnp-4682	258	2	on	on	ADP
fnp-4682	258	3	the	the	DET
fnp-4682	258	4	biopsy	biopsy	NOUN
fnp-4682	258	5	findings	finding	NOUN
fnp-4682	258	6	,	,	PUNCT
fnp-4682	258	7	the	the	DET
fnp-4682	258	8	patient	patient	ADJ
fnp-4682	258	9	underwent	undergo	VERB
fnp-4682	258	10	genetic	genetic	ADJ
fnp-4682	258	11	testing	testing	NOUN
fnp-4682	258	12	for	for	ADP
fnp-4682	258	13	fshd	fshd	ADJ
fnp-4682	258	14	that	that	PRON
fnp-4682	258	15	showed	show	VERB
fnp-4682	258	16	pathogenic	pathogenic	ADJ
fnp-4682	258	17	d4z4	d4z4	PUNCT
fnp-4682	258	18	repeat	repeat	NOUN
fnp-4682	258	19	contraction	contraction	NOUN
fnp-4682	258	20	(	(	PUNCT
fnp-4682	258	21	8	8	NUM
fnp-4682	258	22	repeats	repeat	NOUN
fnp-4682	258	23	)	)	PUNCT
fnp-4682	258	24	detected	detect	VERB
fnp-4682	258	25	on	on	ADP
fnp-4682	258	26	a	a	DET
fnp-4682	258	27	4qa	4qa	ADJ
fnp-4682	258	28	permissive	permissive	ADJ
fnp-4682	258	29	haplotype	haplotype	NOUN
fnp-4682	258	30	,	,	PUNCT
fnp-4682	258	31	diagnostic	diagnostic	ADJ
fnp-4682	258	32	of	of	ADP
fnp-4682	258	33	fshd1	fshd1	PROPN
fnp-4682	258	34	.	.	PUNCT
fnp-4682	259	1	all	all	DET
fnp-4682	259	2	stains	stain	NOUN
fnp-4682	259	3	were	be	AUX
fnp-4682	259	4	performed	perform	VERB
fnp-4682	259	5	on	on	ADP
fnp-4682	259	6	cryosections	cryosection	NOUN
fnp-4682	259	7	;	;	PUNCT
fnp-4682	259	8	scale	scale	NOUN
fnp-4682	259	9	bar	bar	NOUN
fnp-4682	259	10	,	,	PUNCT
fnp-4682	259	11	50	50	NUM
fnp-4682	259	12	µm	µm	NOUN
fnp-4682	259	13	.	.	PUNCT
fnp-4682	259	14	myotonic	myotonic	ADJ
fnp-4682	259	15	dystrophy	dystrophy	NOUN
fnp-4682	259	16	(	(	PUNCT
fnp-4682	259	17	dystrophia	dystrophia	PROPN
fnp-4682	259	18	myotonica	myotonica	PROPN
fnp-4682	259	19	;	;	PUNCT
fnp-4682	259	20	dm	dm	X
fnp-4682	259	21	)	)	PUNCT
fnp-4682	259	22	is	be	AUX
fnp-4682	259	23	the	the	DET
fnp-4682	259	24	most	most	ADV
fnp-4682	259	25	common	common	ADJ
fnp-4682	259	26	muscular	muscular	ADJ
fnp-4682	259	27	dystrophy	dystrophy	NOUN
fnp-4682	259	28	in	in	ADP
fnp-4682	259	29	adults	adult	NOUN
fnp-4682	259	30	and	and	CCONJ
fnp-4682	259	31	the	the	DET
fnp-4682	259	32	second	second	ADJ
fnp-4682	259	33	most	most	ADV
fnp-4682	259	34	common	common	ADJ
fnp-4682	259	35	muscular	muscular	ADJ
fnp-4682	259	36	dystrophy	dystrophy	NOUN
fnp-4682	259	37	overall	overall	ADJ
fnp-4682	259	38	.	.	PUNCT
fnp-4682	260	1	as	as	ADP
fnp-4682	260	2	with	with	ADP
fnp-4682	260	3	fshd	fshd	ADJ
fnp-4682	260	4	,	,	PUNCT
fnp-4682	260	5	there	there	PRON
fnp-4682	260	6	are	be	VERB
fnp-4682	260	7	two	two	NUM
fnp-4682	260	8	distinct	distinct	ADJ
fnp-4682	260	9	dm	dm	PROPN
fnp-4682	260	10	subtypes	subtype	NOUN
fnp-4682	260	11	,	,	PUNCT
fnp-4682	260	12	dm1	dm1	PROPN
fnp-4682	260	13	(	(	PUNCT
fnp-4682	260	14	which	which	PRON
fnp-4682	260	15	accounts	account	VERB
fnp-4682	260	16	for	for	ADP
fnp-4682	260	17	>	>	X
fnp-4682	260	18	95	95	NUM
fnp-4682	260	19	%	%	NOUN
fnp-4682	260	20	of	of	ADP
fnp-4682	260	21	cases	case	NOUN
fnp-4682	260	22	)	)	PUNCT
fnp-4682	260	23	and	and	CCONJ
fnp-4682	260	24	dm2	dm2	PROPN
fnp-4682	260	25	(	(	PUNCT
fnp-4682	260	26	which	which	PRON
fnp-4682	260	27	is	be	AUX
fnp-4682	260	28	much	much	ADV
fnp-4682	260	29	rarer	rare	ADJ
fnp-4682	260	30	)	)	PUNCT
fnp-4682	260	31	.	.	PUNCT
fnp-4682	261	1	although	although	SCONJ
fnp-4682	261	2	their	their	PRON
fnp-4682	261	3	clinical	clinical	ADJ
fnp-4682	261	4	features	feature	NOUN
fnp-4682	261	5	and	and	CCONJ
fnp-4682	261	6	causative	causative	ADJ
fnp-4682	261	7	genes	gene	NOUN
fnp-4682	261	8	differ	differ	VERB
fnp-4682	261	9	,	,	PUNCT
fnp-4682	261	10	both	both	CCONJ
fnp-4682	261	11	dm1	dm1	PROPN
fnp-4682	261	12	and	and	CCONJ
fnp-4682	261	13	dm2	dm2	PROPN
fnp-4682	261	14	are	be	AUX
fnp-4682	261	15	short	short	ADJ
fnp-4682	261	16	tandem	tandem	NOUN
fnp-4682	261	17	repeat	repeat	NOUN
fnp-4682	261	18	(	(	PUNCT
fnp-4682	261	19	str	str	NOUN
fnp-4682	261	20	)	)	PUNCT
fnp-4682	261	21	expansion	expansion	NOUN
fnp-4682	261	22	diseases	disease	NOUN
fnp-4682	261	23	:	:	PUNCT
fnp-4682	261	24	dm1	dm1	PROPN
fnp-4682	261	25	is	be	AUX
fnp-4682	261	26	caused	cause	VERB
fnp-4682	261	27	by	by	ADP
fnp-4682	261	28	expansion	expansion	NOUN
fnp-4682	261	29	of	of	ADP
fnp-4682	261	30	the	the	DET
fnp-4682	261	31	ctg	ctg	NOUN
fnp-4682	261	32	repeat	repeat	NOUN
fnp-4682	261	33	in	in	ADP
fnp-4682	261	34	the	the	DET
fnp-4682	261	35	3	3	NUM
fnp-4682	261	36	’	'	PUNCT
fnp-4682	261	37	untranslated	untranslated	ADJ
fnp-4682	261	38	region	region	NOUN
fnp-4682	261	39	of	of	ADP
fnp-4682	261	40	dmpk	dmpk	NOUN
fnp-4682	261	41	gene	gene	NOUN
fnp-4682	261	42	,	,	PUNCT
fnp-4682	261	43	while	while	SCONJ
fnp-4682	261	44	dm2	dm2	PROPN
fnp-4682	261	45	is	be	AUX
fnp-4682	261	46	caused	cause	VERB
fnp-4682	261	47	by	by	ADP
fnp-4682	261	48	expansion	expansion	NOUN
fnp-4682	261	49	of	of	ADP
fnp-4682	261	50	the	the	DET
fnp-4682	261	51	cctg	cctg	NOUN
fnp-4682	261	52	repeat	repeat	VERB
fnp-4682	261	53	in	in	ADP
fnp-4682	261	54	intron	intron	ADJ
fnp-4682	261	55	1	1	NUM
fnp-4682	261	56	of	of	ADP
fnp-4682	261	57	cnbp	cnbp	NOUN
fnp-4682	261	58	/	/	SYM
fnp-4682	261	59	znf9	znf9	PROPN
fnp-4682	261	60	gene	gene	NOUN
fnp-4682	261	61	.	.	PUNCT
fnp-4682	262	1	interestingly	interestingly	ADV
fnp-4682	262	2	,	,	PUNCT
fnp-4682	262	3	the	the	DET
fnp-4682	262	4	mechanism	mechanism	NOUN
fnp-4682	262	5	of	of	ADP
fnp-4682	262	6	myotonia	myotonia	NOUN
fnp-4682	262	7	is	be	AUX
fnp-4682	262	8	the	the	DET
fnp-4682	262	9	same	same	ADJ
fnp-4682	262	10	in	in	ADP
fnp-4682	262	11	both	both	DET
fnp-4682	262	12	dm	dm	PROPN
fnp-4682	262	13	subtypes	subtype	NOUN
fnp-4682	262	14	:	:	PUNCT
fnp-4682	262	15	mutant	mutant	ADJ
fnp-4682	262	16	rnas	rnas	PROPN
fnp-4682	262	17	sequester	sequester	PROPN
fnp-4682	262	18	rna	rna	NOUN
fnp-4682	262	19	-	-	PUNCT
fnp-4682	262	20	binding	bind	VERB
fnp-4682	262	21	and	and	CCONJ
fnp-4682	262	22	processing	processing	NOUN
fnp-4682	262	23	proteins	protein	NOUN
fnp-4682	262	24	,	,	PUNCT
fnp-4682	262	25	leading	lead	VERB
fnp-4682	262	26	to	to	ADP
fnp-4682	262	27	incorrect	incorrect	ADJ
fnp-4682	262	28	splicing	splicing	NOUN
fnp-4682	262	29	of	of	ADP
fnp-4682	262	30	clc-1	clc-1	PUNCT
fnp-4682	262	31	chloride	chloride	NOUN
fnp-4682	262	32	channel	channel	NOUN
fnp-4682	262	33	(	(	PUNCT
fnp-4682	262	34	which	which	PRON
fnp-4682	262	35	is	be	AUX
fnp-4682	262	36	required	require	VERB
fnp-4682	262	37	for	for	ADP
fnp-4682	262	38	the	the	DET
fnp-4682	262	39	maintenance	maintenance	NOUN
fnp-4682	262	40	of	of	ADP
fnp-4682	262	41	normal	normal	ADJ
fnp-4682	262	42	resting	rest	VERB
fnp-4682	262	43	membrane	membrane	NOUN
fnp-4682	262	44	potential	potential	NOUN
fnp-4682	262	45	)	)	PUNCT
fnp-4682	262	46	.	.	PUNCT
fnp-4682	263	1	histopathology	histopathology	NOUN
fnp-4682	263	2	of	of	ADP
fnp-4682	263	3	dm1	dm1	PROPN
fnp-4682	263	4	and	and	CCONJ
fnp-4682	263	5	dm2	dm2	PROPN
fnp-4682	263	6	is	be	AUX
fnp-4682	263	7	strikingly	strikingly	ADV
fnp-4682	263	8	similar	similar	ADJ
fnp-4682	263	9	,	,	PUNCT
fnp-4682	263	10	with	with	ADP
fnp-4682	263	11	very	very	ADV
fnp-4682	263	12	high	high	ADJ
fnp-4682	263	13	internal	internal	ADJ
fnp-4682	263	14	nucleation	nucleation	NOUN
fnp-4682	263	15	and	and	CCONJ
fnp-4682	263	16	frequent	frequent	ADJ
fnp-4682	263	17	subsarcolemmal	subsarcolemmal	ADJ
fnp-4682	263	18	nuclear	nuclear	ADJ
fnp-4682	263	19	aggregates	aggregate	NOUN
fnp-4682	263	20	in	in	ADP
fnp-4682	263	21	the	the	DET
fnp-4682	263	22	setting	setting	NOUN
fnp-4682	263	23	of	of	ADP
fnp-4682	263	24	usual	usual	ADJ
fnp-4682	263	25	dystrophic	dystrophic	ADJ
fnp-4682	263	26	changes	change	NOUN
fnp-4682	263	27	(	(	PUNCT
fnp-4682	263	28	fig	fig	NOUN
fnp-4682	263	29	.	.	PUNCT
fnp-4682	264	1	7	7	NUM
fnp-4682	264	2	)	)	PUNCT
fnp-4682	264	3	;	;	PUNCT
fnp-4682	264	4	therefore	therefore	ADV
fnp-4682	264	5	,	,	PUNCT
fnp-4682	264	6	the	the	DET
fnp-4682	264	7	definitive	definitive	ADJ
fnp-4682	264	8	diagnosis	diagnosis	NOUN
fnp-4682	264	9	requires	require	VERB
fnp-4682	264	10	genetic	genetic	ADJ
fnp-4682	264	11	testing	testing	NOUN
fnp-4682	264	12	.	.	PUNCT
fnp-4682	265	1	although	although	SCONJ
fnp-4682	265	2	small	small	ADJ
fnp-4682	265	3	str	str	NOUN
fnp-4682	265	4	expansions	expansion	NOUN
fnp-4682	265	5	(	(	PUNCT
fnp-4682	265	6	<	<	X
fnp-4682	265	7	300	300	NUM
fnp-4682	265	8	bp	bp	NOUN
fnp-4682	265	9	)	)	PUNCT
fnp-4682	265	10	can	can	AUX
fnp-4682	265	11	be	be	AUX
fnp-4682	265	12	detected	detect	VERB
fnp-4682	265	13	by	by	ADP
fnp-4682	265	14	conventional	conventional	ADJ
fnp-4682	265	15	pcr	pcr	NOUN
fnp-4682	265	16	,	,	PUNCT
fnp-4682	265	17	genetic	genetic	ADJ
fnp-4682	265	18	diagnosis	diagnosis	NOUN
fnp-4682	265	19	of	of	ADP
fnp-4682	265	20	most	most	ADJ
fnp-4682	265	21	str	str	NOUN
fnp-4682	265	22	expansion	expansion	NOUN
fnp-4682	265	23	disorders	disorder	NOUN
fnp-4682	265	24	(	(	PUNCT
fnp-4682	265	25	which	which	PRON
fnp-4682	265	26	in	in	ADP
fnp-4682	265	27	addition	addition	NOUN
fnp-4682	265	28	to	to	ADP
fnp-4682	265	29	dm1	dm1	PROPN
fnp-4682	265	30	and	and	CCONJ
fnp-4682	265	31	dm2	dm2	PROPN
fnp-4682	265	32	include	include	VERB
fnp-4682	265	33	huntington	huntington	PROPN
fnp-4682	265	34	’s	’s	PART
fnp-4682	265	35	disease	disease	NOUN
fnp-4682	265	36	,	,	PUNCT
fnp-4682	265	37	fragile	fragile	ADJ
fnp-4682	265	38	x	x	NOUN
fnp-4682	265	39	syndrome	syndrome	NOUN
fnp-4682	265	40	,	,	PUNCT
fnp-4682	265	41	hereditary	hereditary	ADJ
fnp-4682	265	42	cerebellar	cerebellar	ADJ
fnp-4682	265	43	ataxias	ataxias	PROPN
fnp-4682	265	44	,	,	PUNCT
fnp-4682	265	45	c9orf72	c9orf72	NOUN
fnp-4682	265	46	-	-	PUNCT
fnp-4682	265	47	related	relate	VERB
fnp-4682	265	48	als	als	NOUN
fnp-4682	265	49	/	/	SYM
fnp-4682	265	50	frontotemporal	frontotemporal	ADJ
fnp-4682	265	51	degeneration	degeneration	NOUN
fnp-4682	265	52	,	,	PUNCT
fnp-4682	265	53	and	and	CCONJ
fnp-4682	265	54	other	other	ADJ
fnp-4682	265	55	neurologic	neurologic	ADJ
fnp-4682	265	56	diseases	disease	NOUN
fnp-4682	265	57	)	)	PUNCT
fnp-4682	265	58	currently	currently	ADV
fnp-4682	265	59	relies	rely	VERB
fnp-4682	265	60	on	on	ADP
fnp-4682	265	61	southern	southern	ADJ
fnp-4682	265	62	blotting	blotting	NOUN
fnp-4682	265	63	and/or	and/or	CCONJ
fnp-4682	265	64	tandem	tandem	PROPN
fnp-4682	265	65	repeat	repeat	NOUN
fnp-4682	265	66	-	-	PUNCT
fnp-4682	265	67	primed	prime	VERB
fnp-4682	265	68	pcr	pcr	NOUN
fnp-4682	265	69	,	,	PUNCT
fnp-4682	265	70	and	and	CCONJ
fnp-4682	265	71	therefore	therefore	ADV
fnp-4682	265	72	faces	face	VERB
fnp-4682	265	73	many	many	ADJ
fnp-4682	265	74	challenges	challenge	NOUN
fnp-4682	265	75	already	already	ADV
fnp-4682	265	76	described	describe	VERB
fnp-4682	265	77	for	for	ADP
fnp-4682	265	78	fshd	fshd	ADJ
fnp-4682	265	79	in	in	ADP
fnp-4682	265	80	addition	addition	NOUN
fnp-4682	265	81	to	to	ADP
fnp-4682	265	82	requiring	require	VERB
fnp-4682	265	83	separate	separate	ADJ
fnp-4682	265	84	probes	probe	NOUN
fnp-4682	265	85	and/or	and/or	CCONJ
fnp-4682	265	86	primers	primer	NOUN
fnp-4682	265	87	for	for	ADP
fnp-4682	265	88	each	each	DET
fnp-4682	265	89	str	str	NOUN
fnp-4682	265	90	.	.	PUNCT
fnp-4682	266	1	these	these	DET
fnp-4682	266	2	challenges	challenge	NOUN
fnp-4682	266	3	are	be	AUX
fnp-4682	266	4	either	either	ADV
fnp-4682	266	5	solved	solve	VERB
fnp-4682	266	6	or	or	CCONJ
fnp-4682	266	7	bypassed	bypass	VERB
fnp-4682	266	8	by	by	ADP
fnp-4682	266	9	the	the	DET
fnp-4682	266	10	new	new	ADJ
fnp-4682	266	11	genetic	genetic	ADJ
fnp-4682	266	12	strategy	strategy	NOUN
fnp-4682	266	13	developed	develop	VERB
fnp-4682	266	14	by	by	ADP
fnp-4682	266	15	stevanovski	stevanovski	PROPN
fnp-4682	266	16	et	et	PROPN
fnp-4682	266	17	al	al	PROPN
fnp-4682	266	18	.	.	PROPN
fnp-4682	266	19	,	,	PUNCT
fnp-4682	266	20	which	which	PRON
fnp-4682	266	21	relies	rely	VERB
fnp-4682	266	22	on	on	ADP
fnp-4682	266	23	programmable	programmable	ADJ
fnp-4682	266	24	targeted	target	VERB
fnp-4682	266	25	long	long	ADV
fnp-4682	266	26	-	-	PUNCT
fnp-4682	266	27	read	read	NOUN
fnp-4682	266	28	nanopore	nanopore	ADV
fnp-4682	266	29	sequencing	sequence	VERB
fnp-4682	266	30	to	to	PART
fnp-4682	266	31	genotype	genotype	VERB
fnp-4682	266	32	all	all	DET
fnp-4682	266	33	known	know	VERB
fnp-4682	266	34	neuropathogenic	neuropathogenic	ADJ
fnp-4682	266	35	strs	str	NOUN
fnp-4682	266	36	in	in	ADP
fnp-4682	266	37	parallel	parallel	NOUN
fnp-4682	266	38	,	,	PUNCT
fnp-4682	266	39	using	use	VERB
fnp-4682	266	40	a	a	DET
fnp-4682	266	41	single	single	ADJ
fnp-4682	266	42	molecular	molecular	ADJ
fnp-4682	266	43	assay	assay	NOUN
fnp-4682	266	44	(	(	PUNCT
fnp-4682	266	45	stevanovski	stevanovski	NOUN
fnp-4682	266	46	et	et	PROPN
fnp-4682	266	47	al	al	PROPN
fnp-4682	266	48	.	.	PROPN
fnp-4682	266	49	,	,	PUNCT
fnp-4682	266	50	2022	2022	NUM
fnp-4682	266	51	)	)	PUNCT
fnp-4682	266	52	.	.	PUNCT
fnp-4682	267	1	one	one	NUM
fnp-4682	267	2	particularly	particularly	ADV
fnp-4682	267	3	appealing	appealing	ADJ
fnp-4682	267	4	feature	feature	NOUN
fnp-4682	267	5	of	of	ADP
fnp-4682	267	6	the	the	DET
fnp-4682	267	7	platform	platform	NOUN
fnp-4682	267	8	used	use	VERB
fnp-4682	267	9	for	for	ADP
fnp-4682	267	10	this	this	DET
fnp-4682	267	11	assay	assay	NOUN
fnp-4682	267	12	is	be	AUX
fnp-4682	267	13	that	that	SCONJ
fnp-4682	267	14	it	it	PRON
fnp-4682	267	15	permits	permit	VERB
fnp-4682	267	16	flexible	flexible	ADJ
fnp-4682	267	17	inclusion	inclusion	NOUN
fnp-4682	267	18	of	of	ADP
fnp-4682	267	19	targets	target	NOUN
fnp-4682	267	20	,	,	PUNCT
fnp-4682	267	21	so	so	SCONJ
fnp-4682	267	22	that	that	SCONJ
fnp-4682	267	23	a	a	DET
fnp-4682	267	24	specific	specific	ADJ
fnp-4682	267	25	assay	assay	NOUN
fnp-4682	267	26	used	use	VERB
fnp-4682	267	27	for	for	ADP
fnp-4682	267	28	any	any	DET
fnp-4682	267	29	given	give	VERB
fnp-4682	267	30	patient	patient	NOUN
fnp-4682	267	31	can	can	AUX
fnp-4682	267	32	be	be	AUX
fnp-4682	267	33	individually	individually	ADV
fnp-4682	267	34	tailored	tailor	VERB
fnp-4682	267	35	based	base	VERB
fnp-4682	267	36	on	on	ADP
fnp-4682	267	37	the	the	DET
fnp-4682	267	38	clinician	clinician	NOUN
fnp-4682	267	39	’s	’s	PART
fnp-4682	267	40	input	input	NOUN
fnp-4682	267	41	and/or	and/or	CCONJ
fnp-4682	267	42	the	the	DET
fnp-4682	267	43	patient	patient	NOUN
fnp-4682	267	44	’s	’s	PART
fnp-4682	267	45	preferences	preference	NOUN
fnp-4682	267	46	;	;	PUNCT
fnp-4682	267	47	another	another	PRON
fnp-4682	267	48	is	be	AUX
fnp-4682	267	49	that	that	SCONJ
fnp-4682	267	50	sequencing	sequencing	NOUN
fnp-4682	267	51	can	can	AUX
fnp-4682	267	52	be	be	AUX
fnp-4682	267	53	combined	combine	VERB
fnp-4682	267	54	with	with	ADP
fnp-4682	267	55	methylation	methylation	NOUN
fnp-4682	267	56	profiling	profiling	NOUN
fnp-4682	267	57	,	,	PUNCT
fnp-4682	267	58	providing	provide	VERB
fnp-4682	267	59	epigenetic	epigenetic	NOUN
fnp-4682	267	60	as	as	ADV
fnp-4682	267	61	well	well	ADV
fnp-4682	267	62	as	as	ADP
fnp-4682	267	63	genetic	genetic	ADJ
fnp-4682	267	64	information	information	NOUN
fnp-4682	267	65	in	in	ADP
fnp-4682	267	66	a	a	DET
fnp-4682	267	67	single	single	ADJ
fnp-4682	267	68	step	step	NOUN
fnp-4682	267	69	.	.	PUNCT
fnp-4682	268	1	as	as	ADP
fnp-4682	268	2	a	a	DET
fnp-4682	268	3	result	result	NOUN
fnp-4682	268	4	,	,	PUNCT
fnp-4682	268	5	this	this	DET
fnp-4682	268	6	new	new	ADJ
fnp-4682	268	7	genetic	genetic	ADJ
fnp-4682	268	8	testing	testing	NOUN
fnp-4682	268	9	approach	approach	NOUN
fnp-4682	268	10	will	will	AUX
fnp-4682	268	11	likely	likely	ADV
fnp-4682	268	12	advance	advance	VERB
fnp-4682	268	13	basic	basic	ADJ
fnp-4682	268	14	research	research	NOUN
fnp-4682	268	15	in	in	ADP
fnp-4682	268	16	addition	addition	NOUN
fnp-4682	268	17	to	to	ADP
fnp-4682	268	18	patient	patient	ADJ
fnp-4682	268	19	care	care	NOUN
fnp-4682	268	20	:	:	PUNCT
fnp-4682	268	21	much	much	ADJ
fnp-4682	268	22	remains	remain	VERB
fnp-4682	268	23	to	to	PART
fnp-4682	268	24	be	be	AUX
fnp-4682	268	25	learned	learn	VERB
fnp-4682	268	26	about	about	ADP
fnp-4682	268	27	the	the	DET
fnp-4682	268	28	fundamental	fundamental	ADJ
fnp-4682	268	29	biology	biology	NOUN
fnp-4682	268	30	of	of	ADP
fnp-4682	268	31	the	the	DET
fnp-4682	268	32	str	str	NOUN
fnp-4682	268	33	expansion	expansion	NOUN
fnp-4682	268	34	disorders	disorder	NOUN
fnp-4682	268	35	and	and	CCONJ
fnp-4682	268	36	the	the	DET
fnp-4682	268	37	key	key	ADJ
fnp-4682	268	38	variables	variable	NOUN
fnp-4682	268	39	that	that	PRON
fnp-4682	268	40	distinguish	distinguish	VERB
fnp-4682	268	41	normal	normal	ADJ
fnp-4682	268	42	and	and	CCONJ
fnp-4682	268	43	disease	disease	NOUN
fnp-4682	268	44	-	-	PUNCT
fnp-4682	268	45	causing	cause	VERB
fnp-4682	268	46	alleles	allele	NOUN
fnp-4682	268	47	,	,	PUNCT
fnp-4682	268	48	and	and	CCONJ
fnp-4682	268	49	the	the	DET
fnp-4682	268	50	availability	availability	NOUN
fnp-4682	268	51	of	of	ADP
fnp-4682	268	52	a	a	DET
fnp-4682	268	53	relatively	relatively	ADV
fnp-4682	268	54	inexpensive	inexpensive	ADJ
fnp-4682	268	55	high	high	ADJ
fnp-4682	268	56	-	-	PUNCT
fnp-4682	268	57	resolution	resolution	NOUN
fnp-4682	268	58	molecular	molecular	ADJ
fnp-4682	268	59	str	str	NOUN
fnp-4682	268	60	assay	assay	NOUN
fnp-4682	268	61	should	should	AUX
fnp-4682	268	62	accelerate	accelerate	VERB
fnp-4682	268	63	research	research	NOUN
fnp-4682	268	64	progress	progress	NOUN
fnp-4682	268	65	in	in	ADP
fnp-4682	268	66	all	all	DET
fnp-4682	268	67	these	these	DET
fnp-4682	268	68	areas	area	NOUN
fnp-4682	268	69	.	.	PUNCT
fnp-4682	269	1	figure	figure	VERB
fnp-4682	269	2	7	7	NUM
fnp-4682	269	3	.	.	PUNCT
fnp-4682	270	1	histologic	histologic	PROPN
fnp-4682	270	2	findings	finding	NOUN
fnp-4682	270	3	in	in	ADP
fnp-4682	270	4	myotonic	myotonic	ADJ
fnp-4682	270	5	dystrophy	dystrophy	NOUN
fnp-4682	270	6	(	(	PUNCT
fnp-4682	270	7	dm	dm	NOUN
fnp-4682	270	8	)	)	PUNCT
fnp-4682	270	9	.	.	PUNCT
fnp-4682	271	1	(	(	PUNCT
fnp-4682	271	2	a	a	X
fnp-4682	271	3	)	)	PUNCT
fnp-4682	271	4	a	a	DET
fnp-4682	271	5	representative	representative	ADJ
fnp-4682	271	6	h&e	h&e	NOUN
fnp-4682	271	7	-	-	PUNCT
fnp-4682	271	8	stained	stain	VERB
fnp-4682	271	9	formalin	formalin	NOUN
fnp-4682	271	10	-	-	PUNCT
fnp-4682	271	11	fixed	fix	VERB
fnp-4682	271	12	,	,	PUNCT
fnp-4682	271	13	paraffin	paraffin	NOUN
fnp-4682	271	14	embedded	embed	VERB
fnp-4682	271	15	section	section	NOUN
fnp-4682	271	16	shows	show	VERB
fnp-4682	271	17	fiber	fiber	NOUN
fnp-4682	271	18	size	size	NOUN
fnp-4682	271	19	variation	variation	NOUN
fnp-4682	271	20	,	,	PUNCT
fnp-4682	271	21	endomysial	endomysial	ADJ
fnp-4682	271	22	fibrosis	fibrosis	NOUN
fnp-4682	271	23	with	with	ADP
fnp-4682	271	24	fatty	fatty	NOUN
fnp-4682	271	25	infiltration	infiltration	NOUN
fnp-4682	271	26	,	,	PUNCT
fnp-4682	271	27	frequent	frequent	ADJ
fnp-4682	271	28	subsarcolemmal	subsarcolemmal	ADJ
fnp-4682	271	29	nuclear	nuclear	ADJ
fnp-4682	271	30	aggregates	aggregate	NOUN
fnp-4682	271	31	,	,	PUNCT
fnp-4682	271	32	and	and	CCONJ
fnp-4682	271	33	nuclei	nucleus	NOUN
fnp-4682	271	34	running	run	VERB
fnp-4682	271	35	in	in	ADP
fnp-4682	271	36	chains	chain	NOUN
fnp-4682	271	37	along	along	ADP
fnp-4682	271	38	the	the	DET
fnp-4682	271	39	longitudinal	longitudinal	ADJ
fnp-4682	271	40	fiber	fiber	NOUN
fnp-4682	271	41	axis	axis	NOUN
fnp-4682	271	42	(	(	PUNCT
fnp-4682	271	43	arrowhead	arrowhead	NOUN
fnp-4682	271	44	)	)	PUNCT
fnp-4682	271	45	.	.	PUNCT
fnp-4682	272	1	(	(	PUNCT
fnp-4682	272	2	b	b	X
fnp-4682	272	3	)	)	PUNCT
fnp-4682	272	4	an	an	DET
fnp-4682	272	5	h&e	h&e	PROPN
fnp-4682	272	6	-	-	PUNCT
fnp-4682	272	7	stained	stain	VERB
fnp-4682	272	8	cryosection	cryosection	NOUN
fnp-4682	272	9	shows	show	VERB
fnp-4682	272	10	similar	similar	ADJ
fnp-4682	272	11	findings	finding	NOUN
fnp-4682	272	12	,	,	PUNCT
fnp-4682	272	13	with	with	ADP
fnp-4682	272	14	prominent	prominent	ADJ
fnp-4682	272	15	subsarcolemmal	subsarcolemmal	ADJ
fnp-4682	272	16	nuclear	nuclear	ADJ
fnp-4682	272	17	aggregates	aggregate	NOUN
fnp-4682	272	18	and	and	CCONJ
fnp-4682	272	19	a	a	DET
fnp-4682	272	20	marked	mark	VERB
fnp-4682	272	21	increase	increase	NOUN
fnp-4682	272	22	in	in	ADP
fnp-4682	272	23	internal	internal	ADJ
fnp-4682	272	24	nuclei	nucleus	NOUN
fnp-4682	272	25	.	.	PUNCT
fnp-4682	273	1	(	(	PUNCT
fnp-4682	273	2	c	c	X
fnp-4682	273	3	)	)	PUNCT
fnp-4682	273	4	an	an	DET
fnp-4682	273	5	acid	acid	NOUN
fnp-4682	273	6	phosphatase	phosphatase	NOUN
fnp-4682	273	7	-	-	PUNCT
fnp-4682	273	8	stained	stain	VERB
fnp-4682	273	9	cryosection	cryosection	NOUN
fnp-4682	273	10	shows	show	VERB
fnp-4682	273	11	a	a	DET
fnp-4682	273	12	fiber	fiber	NOUN
fnp-4682	273	13	with	with	ADP
fnp-4682	273	14	prominent	prominent	ADJ
fnp-4682	273	15	sarcoplasmic	sarcoplasmic	NOUN
fnp-4682	273	16	acid	acid	NOUN
fnp-4682	273	17	phosphatase	phosphatase	NOUN
fnp-4682	273	18	-	-	PUNCT
fnp-4682	273	19	positive	positive	ADJ
fnp-4682	273	20	granules	granule	NOUN
fnp-4682	273	21	(	(	PUNCT
fnp-4682	273	22	asterisk	asterisk	NOUN
fnp-4682	273	23	)	)	PUNCT
fnp-4682	273	24	.	.	PUNCT
fnp-4682	274	1	based	base	VERB
fnp-4682	274	2	on	on	ADP
fnp-4682	274	3	the	the	DET
fnp-4682	274	4	biopsy	biopsy	NOUN
fnp-4682	274	5	findings	finding	NOUN
fnp-4682	274	6	,	,	PUNCT
fnp-4682	274	7	the	the	DET
fnp-4682	274	8	patient	patient	ADJ
fnp-4682	274	9	underwent	undergo	VERB
fnp-4682	274	10	genetic	genetic	ADJ
fnp-4682	274	11	testing	testing	NOUN
fnp-4682	274	12	for	for	ADP
fnp-4682	274	13	myotonic	myotonic	ADJ
fnp-4682	274	14	dystrophy	dystrophy	NOUN
fnp-4682	274	15	that	that	PRON
fnp-4682	274	16	showed	show	VERB
fnp-4682	274	17	>	>	SYM
fnp-4682	274	18	15600	15600	NUM
fnp-4682	274	19	repeats	repeat	NOUN
fnp-4682	274	20	in	in	ADP
fnp-4682	274	21	one	one	NUM
fnp-4682	274	22	allele	allele	NOUN
fnp-4682	274	23	of	of	ADP
fnp-4682	274	24	cnbp	cnbp	PROPN
fnp-4682	274	25	/	/	SYM
fnp-4682	274	26	znf9	znf9	PROPN
fnp-4682	274	27	gene	gene	NOUN
fnp-4682	274	28	,	,	PUNCT
fnp-4682	274	29	diagnostic	diagnostic	NOUN
fnp-4682	274	30	of	of	ADP
fnp-4682	274	31	dm2	dm2	PROPN
fnp-4682	274	32	.	.	PUNCT
fnp-4682	275	1	(	(	PUNCT
fnp-4682	275	2	histologic	histologic	PROPN
fnp-4682	275	3	findings	finding	NOUN
fnp-4682	275	4	in	in	ADP
fnp-4682	275	5	dm1	dm1	PROPN
fnp-4682	275	6	are	be	AUX
fnp-4682	275	7	very	very	ADV
fnp-4682	275	8	similar	similar	ADJ
fnp-4682	275	9	.	.	PUNCT
fnp-4682	275	10	)	)	PUNCT
fnp-4682	276	1	scale	scale	NOUN
fnp-4682	276	2	bars	bar	NOUN
fnp-4682	276	3	:	:	PUNCT
fnp-4682	276	4	a	a	PRON
fnp-4682	276	5	and	and	CCONJ
fnp-4682	276	6	b	b	NOUN
fnp-4682	276	7	,	,	PUNCT
fnp-4682	276	8	100	100	NUM
fnp-4682	276	9	µm	µm	NUM
fnp-4682	276	10	;	;	PUNCT
fnp-4682	276	11	c	c	X
fnp-4682	276	12	,	,	PUNCT
fnp-4682	276	13	50	50	NUM
fnp-4682	276	14	µm	µm	NOUN
fnp-4682	276	15	.	.	NOUN
fnp-4682	276	16	9	9	NUM
fnp-4682	276	17	.	.	X
fnp-4682	276	18	accumulation	accumulation	NOUN
fnp-4682	276	19	of	of	ADP
fnp-4682	276	20	phosphorylated	phosphorylate	VERB
fnp-4682	276	21	tdp-43	tdp-43	NOUN
fnp-4682	276	22	in	in	ADP
fnp-4682	276	23	motor	motor	NOUN
fnp-4682	276	24	nerves	nerve	NOUN
fnp-4682	276	25	and	and	CCONJ
fnp-4682	276	26	intramuscular	intramuscular	ADJ
fnp-4682	276	27	nerve	nerve	NOUN
fnp-4682	276	28	twigs	twig	NOUN
fnp-4682	276	29	is	be	AUX
fnp-4682	276	30	a	a	DET
fnp-4682	276	31	diagnostic	diagnostic	ADJ
fnp-4682	276	32	marker	marker	NOUN
fnp-4682	276	33	of	of	ADP
fnp-4682	276	34	amyotrophic	amyotrophic	ADJ
fnp-4682	276	35	lateral	lateral	ADJ
fnp-4682	276	36	sclerosis	sclerosis	NOUN
fnp-4682	276	37	als	als	NOUN
fnp-4682	276	38	is	be	AUX
fnp-4682	276	39	a	a	DET
fnp-4682	276	40	neurodegenerative	neurodegenerative	ADJ
fnp-4682	276	41	disease	disease	NOUN
fnp-4682	276	42	that	that	PRON
fnp-4682	276	43	typically	typically	ADV
fnp-4682	276	44	affects	affect	VERB
fnp-4682	276	45	both	both	CCONJ
fnp-4682	276	46	upper	upper	ADJ
fnp-4682	276	47	and	and	CCONJ
fnp-4682	276	48	lower	low	ADJ
fnp-4682	276	49	motor	motor	NOUN
fnp-4682	276	50	neurons	neuron	NOUN
fnp-4682	276	51	and	and	CCONJ
fnp-4682	276	52	is	be	AUX
fnp-4682	276	53	the	the	DET
fnp-4682	276	54	most	most	ADV
fnp-4682	276	55	common	common	ADJ
fnp-4682	276	56	cause	cause	NOUN
fnp-4682	276	57	of	of	ADP
fnp-4682	276	58	motor	motor	NOUN
fnp-4682	276	59	neuron	neuron	PROPN
fnp-4682	276	60	disease	disease	PROPN
fnp-4682	276	61	(	(	PUNCT
fnp-4682	276	62	mnd	mnd	PROPN
fnp-4682	276	63	)	)	PUNCT
fnp-4682	276	64	in	in	ADP
fnp-4682	276	65	adults	adult	NOUN
fnp-4682	276	66	;	;	PUNCT
fnp-4682	276	67	pathologically	pathologically	ADV
fnp-4682	276	68	,	,	PUNCT
fnp-4682	276	69	it	it	PRON
fnp-4682	276	70	is	be	AUX
fnp-4682	276	71	characterized	characterize	VERB
fnp-4682	276	72	by	by	ADP
fnp-4682	276	73	selective	selective	ADJ
fnp-4682	276	74	motor	motor	NOUN
fnp-4682	276	75	neuron	neuron	PROPN
fnp-4682	276	76	loss	loss	NOUN
fnp-4682	276	77	that	that	PRON
fnp-4682	276	78	is	be	AUX
fnp-4682	276	79	accompanied	accompany	VERB
fnp-4682	276	80	by	by	ADP
fnp-4682	276	81	aggregates	aggregate	NOUN
fnp-4682	276	82	of	of	ADP
fnp-4682	276	83	phosphorylated	phosphorylate	VERB
fnp-4682	276	84	tdp-43	tdp-43	PROPN
fnp-4682	276	85	(	(	PUNCT
fnp-4682	276	86	ptdp-43	ptdp-43	PROPN
fnp-4682	276	87	)	)	PUNCT
fnp-4682	276	88	in	in	ADP
fnp-4682	276	89	the	the	DET
fnp-4682	276	90	remaining	remain	VERB
fnp-4682	276	91	motor	motor	NOUN
fnp-4682	276	92	neurons	neuron	NOUN
fnp-4682	276	93	and	and	CCONJ
fnp-4682	276	94	glia	glia	PROPN
fnp-4682	276	95	.	.	PUNCT
fnp-4682	277	1	during	during	ADP
fnp-4682	277	2	life	life	NOUN
fnp-4682	277	3	,	,	PUNCT
fnp-4682	277	4	als	als	VERB
fnp-4682	277	5	diagnosis	diagnosis	NOUN
fnp-4682	277	6	is	be	AUX
fnp-4682	277	7	based	base	VERB
fnp-4682	277	8	on	on	ADP
fnp-4682	277	9	the	the	DET
fnp-4682	277	10	clinical	clinical	ADJ
fnp-4682	277	11	criteria	criterion	NOUN
fnp-4682	277	12	;	;	PUNCT
fnp-4682	277	13	however	however	ADV
fnp-4682	277	14	,	,	PUNCT
fnp-4682	277	15	there	there	PRON
fnp-4682	277	16	is	be	VERB
fnp-4682	277	17	a	a	DET
fnp-4682	277	18	significant	significant	ADJ
fnp-4682	277	19	phenotypic	phenotypic	ADJ
fnp-4682	277	20	heterogeneity	heterogeneity	NOUN
fnp-4682	277	21	among	among	ADP
fnp-4682	277	22	als	als	NOUN
fnp-4682	277	23	patients	patient	NOUN
fnp-4682	277	24	,	,	PUNCT
fnp-4682	277	25	and	and	CCONJ
fnp-4682	277	26	up	up	ADV
fnp-4682	277	27	to	to	PART
fnp-4682	277	28	20	20	NUM
fnp-4682	277	29	%	%	NOUN
fnp-4682	277	30	of	of	ADP
fnp-4682	277	31	patients	patient	NOUN
fnp-4682	277	32	with	with	ADP
fnp-4682	277	33	an	an	DET
fnp-4682	277	34	lmn	lmn	NOUN
fnp-4682	277	35	-	-	PUNCT
fnp-4682	277	36	predominant	predominant	ADJ
fnp-4682	277	37	form	form	NOUN
fnp-4682	277	38	of	of	ADP
fnp-4682	277	39	als	al	NOUN
fnp-4682	277	40	are	be	AUX
fnp-4682	277	41	misdiagnosed	misdiagnose	VERB
fnp-4682	277	42	prior	prior	ADV
fnp-4682	277	43	to	to	ADP
fnp-4682	277	44	death	death	NOUN
fnp-4682	277	45	.	.	PUNCT
fnp-4682	278	1	based	base	VERB
fnp-4682	278	2	on	on	ADP
fnp-4682	278	3	the	the	DET
fnp-4682	278	4	recent	recent	ADJ
fnp-4682	278	5	work	work	NOUN
fnp-4682	278	6	from	from	ADP
fnp-4682	278	7	two	two	NUM
fnp-4682	278	8	separate	separate	ADJ
fnp-4682	278	9	research	research	NOUN
fnp-4682	278	10	groups	group	NOUN
fnp-4682	278	11	in	in	ADP
fnp-4682	278	12	italy	italy	PROPN
fnp-4682	278	13	and	and	CCONJ
fnp-4682	278	14	japan	japan	PROPN
fnp-4682	278	15	,	,	PUNCT
fnp-4682	278	16	immunohistochemical	immunohistochemical	ADJ
fnp-4682	278	17	detection	detection	NOUN
fnp-4682	278	18	of	of	ADP
fnp-4682	278	19	ptdp-43	ptdp-43	PROPN
fnp-4682	278	20	aggregates	aggregate	NOUN
fnp-4682	278	21	in	in	ADP
fnp-4682	278	22	motor	motor	NOUN
fnp-4682	278	23	nerve	nerve	NOUN
fnp-4682	278	24	biopsies	biopsy	NOUN
fnp-4682	278	25	(	(	PUNCT
fnp-4682	278	26	riva	riva	PROPN
fnp-4682	278	27	et	et	PROPN
fnp-4682	278	28	al	al	PROPN
fnp-4682	278	29	.	.	PROPN
fnp-4682	278	30	,	,	PUNCT
fnp-4682	278	31	2022	2022	NUM
fnp-4682	278	32	)	)	PUNCT
fnp-4682	278	33	and/or	and/or	CCONJ
fnp-4682	278	34	motor	motor	NOUN
fnp-4682	278	35	nerve	nerve	NOUN
fnp-4682	278	36	twigs	twig	NOUN
fnp-4682	278	37	in	in	ADP
fnp-4682	278	38	muscle	muscle	NOUN
fnp-4682	278	39	biopsies	biopsy	NOUN
fnp-4682	278	40	(	(	PUNCT
fnp-4682	278	41	kurashige	kurashige	PROPN
fnp-4682	278	42	et	et	PROPN
fnp-4682	278	43	al	al	PROPN
fnp-4682	278	44	.	.	PROPN
fnp-4682	278	45	,	,	PUNCT
fnp-4682	278	46	2022	2022	NUM
fnp-4682	278	47	)	)	PUNCT
fnp-4682	278	48	may	may	AUX
fnp-4682	278	49	be	be	AUX
fnp-4682	278	50	a	a	DET
fnp-4682	278	51	useful	useful	ADJ
fnp-4682	278	52	tool	tool	NOUN
fnp-4682	278	53	for	for	ADP
fnp-4682	278	54	closure	closure	NOUN
fnp-4682	278	55	of	of	ADP
fnp-4682	278	56	that	that	DET
fnp-4682	278	57	diagnostic	diagnostic	ADJ
fnp-4682	278	58	gap	gap	NOUN
fnp-4682	278	59	.	.	PUNCT
fnp-4682	279	1	riva	riva	NOUN
fnp-4682	279	2	and	and	CCONJ
fnp-4682	279	3	colleagues	colleague	NOUN
fnp-4682	279	4	performed	perform	VERB
fnp-4682	279	5	a	a	DET
fnp-4682	279	6	retrospective	retrospective	ADJ
fnp-4682	279	7	cohort	cohort	NOUN
fnp-4682	279	8	study	study	NOUN
fnp-4682	279	9	to	to	PART
fnp-4682	279	10	assess	assess	VERB
fnp-4682	279	11	whether	whether	SCONJ
fnp-4682	279	12	tdp-43	tdp-43	VERB
fnp-4682	279	13	accumulation	accumulation	NOUN
fnp-4682	279	14	in	in	ADP
fnp-4682	279	15	motor	motor	NOUN
fnp-4682	279	16	nerve	nerve	NOUN
fnp-4682	279	17	biopsies	biopsy	NOUN
fnp-4682	279	18	can	can	AUX
fnp-4682	279	19	serve	serve	VERB
fnp-4682	279	20	as	as	ADP
fnp-4682	279	21	a	a	DET
fnp-4682	279	22	useful	useful	ADJ
fnp-4682	279	23	biomarker	biomarker	NOUN
fnp-4682	279	24	of	of	ADP
fnp-4682	279	25	als	als	NOUN
fnp-4682	279	26	.	.	PUNCT
fnp-4682	280	1	they	they	PRON
fnp-4682	280	2	retrospectively	retrospectively	ADV
fnp-4682	280	3	reviewed	review	VERB
fnp-4682	280	4	the	the	DET
fnp-4682	280	5	clinical	clinical	ADJ
fnp-4682	280	6	course	course	NOUN
fnp-4682	280	7	of	of	ADP
fnp-4682	280	8	113	113	NUM
fnp-4682	280	9	patients	patient	NOUN
fnp-4682	280	10	who	who	PRON
fnp-4682	280	11	underwent	undergo	VERB
fnp-4682	280	12	a	a	DET
fnp-4682	280	13	diagnostic	diagnostic	ADJ
fnp-4682	280	14	biopsy	biopsy	NOUN
fnp-4682	280	15	of	of	ADP
fnp-4682	280	16	the	the	DET
fnp-4682	280	17	anterior	anterior	ADJ
fnp-4682	280	18	motor	motor	NOUN
fnp-4682	280	19	branch	branch	NOUN
fnp-4682	280	20	of	of	ADP
fnp-4682	280	21	the	the	DET
fnp-4682	280	22	obturator	obturator	NOUN
fnp-4682	280	23	nerve	nerve	NOUN
fnp-4682	280	24	,	,	PUNCT
fnp-4682	280	25	typically	typically	ADV
fnp-4682	280	26	for	for	ADP
fnp-4682	280	27	evaluation	evaluation	NOUN
fnp-4682	280	28	of	of	ADP
fnp-4682	280	29	a	a	DET
fnp-4682	280	30	diagnostically	diagnostically	ADV
fnp-4682	280	31	confusing	confusing	ADJ
fnp-4682	280	32	lmn	lmn	NOUN
fnp-4682	280	33	syndrome	syndrome	NOUN
fnp-4682	280	34	,	,	PUNCT
fnp-4682	280	35	during	during	ADP
fnp-4682	280	36	the	the	DET
fnp-4682	280	37	25	25	NUM
fnp-4682	280	38	-	-	PUNCT
fnp-4682	280	39	year	year	NOUN
fnp-4682	280	40	period	period	NOUN
fnp-4682	280	41	between	between	ADP
fnp-4682	280	42	1994	1994	NUM
fnp-4682	280	43	and	and	CCONJ
fnp-4682	280	44	2019	2019	NUM
fnp-4682	280	45	.	.	PUNCT
fnp-4682	281	1	of	of	ADP
fnp-4682	281	2	these	these	DET
fnp-4682	281	3	113	113	NUM
fnp-4682	281	4	patients	patient	NOUN
fnp-4682	281	5	,	,	PUNCT
fnp-4682	281	6	102	102	NUM
fnp-4682	281	7	had	have	VERB
fnp-4682	281	8	sufficient	sufficient	ADJ
fnp-4682	281	9	clinical	clinical	ADJ
fnp-4682	281	10	data	datum	NOUN
fnp-4682	281	11	to	to	PART
fnp-4682	281	12	be	be	AUX
fnp-4682	281	13	included	include	VERB
fnp-4682	281	14	in	in	ADP
fnp-4682	281	15	the	the	DET
fnp-4682	281	16	study	study	NOUN
fnp-4682	281	17	;	;	PUNCT
fnp-4682	281	18	71	71	NUM
fnp-4682	281	19	(	(	PUNCT
fnp-4682	281	20	69.6	69.6	NUM
fnp-4682	281	21	%	%	NOUN
fnp-4682	281	22	)	)	PUNCT
fnp-4682	281	23	were	be	AUX
fnp-4682	281	24	ultimately	ultimately	ADV
fnp-4682	281	25	diagnosed	diagnose	VERB
fnp-4682	281	26	with	with	ADP
fnp-4682	281	27	als	al	NOUN
fnp-4682	281	28	.	.	PUNCT
fnp-4682	282	1	in	in	ADP
fnp-4682	282	2	the	the	DET
fnp-4682	282	3	first	first	ADJ
fnp-4682	282	4	part	part	NOUN
fnp-4682	282	5	of	of	ADP
fnp-4682	282	6	this	this	DET
fnp-4682	282	7	study	study	NOUN
fnp-4682	282	8	,	,	PUNCT
fnp-4682	282	9	the	the	DET
fnp-4682	282	10	authors	author	NOUN
fnp-4682	282	11	performed	perform	VERB
fnp-4682	282	12	blinded	blind	VERB
fnp-4682	282	13	histopathology	histopathology	NOUN
fnp-4682	282	14	review	review	NOUN
fnp-4682	282	15	of	of	ADP
fnp-4682	282	16	original	original	ADJ
fnp-4682	282	17	slides	slide	NOUN
fnp-4682	282	18	for	for	ADP
fnp-4682	282	19	all	all	DET
fnp-4682	282	20	102	102	NUM
fnp-4682	282	21	study	study	NOUN
fnp-4682	282	22	participants	participant	NOUN
fnp-4682	282	23	;	;	PUNCT
fnp-4682	282	24	61	61	NUM
fnp-4682	282	25	biopsies	biopsy	NOUN
fnp-4682	282	26	were	be	AUX
fnp-4682	282	27	diagnosed	diagnose	VERB
fnp-4682	282	28	as	as	ADP
fnp-4682	282	29	pathologic	pathologic	ADJ
fnp-4682	282	30	mnd	mnd	NOUN
fnp-4682	282	31	,	,	PUNCT
fnp-4682	282	32	16	16	NUM
fnp-4682	282	33	were	be	AUX
fnp-4682	282	34	diagnosed	diagnose	VERB
fnp-4682	282	35	as	as	ADP
fnp-4682	282	36	pathologic	pathologic	ADJ
fnp-4682	282	37	motor	motor	NOUN
fnp-4682	282	38	neuropathy	neuropathy	ADJ
fnp-4682	282	39	,	,	PUNCT
fnp-4682	282	40	while	while	SCONJ
fnp-4682	282	41	25	25	NUM
fnp-4682	282	42	were	be	AUX
fnp-4682	282	43	non	non	ADJ
fnp-4682	282	44	-	-	ADJ
fnp-4682	282	45	diagnostic	diagnostic	ADJ
fnp-4682	282	46	.	.	PUNCT
fnp-4682	283	1	excluding	exclude	VERB
fnp-4682	283	2	the	the	DET
fnp-4682	283	3	cases	case	NOUN
fnp-4682	283	4	with	with	ADP
fnp-4682	283	5	pathologic	pathologic	ADJ
fnp-4682	283	6	diagnosis	diagnosis	NOUN
fnp-4682	283	7	of	of	ADP
fnp-4682	283	8	motor	motor	NOUN
fnp-4682	283	9	neuropathy	neuropathy	ADJ
fnp-4682	283	10	(	(	PUNCT
fnp-4682	283	11	which	which	PRON
fnp-4682	283	12	had	have	VERB
fnp-4682	283	13	100	100	NUM
fnp-4682	283	14	%	%	NOUN
fnp-4682	283	15	sensitivity	sensitivity	NOUN
fnp-4682	283	16	and	and	CCONJ
fnp-4682	283	17	100	100	NUM
fnp-4682	283	18	%	%	NOUN
fnp-4682	283	19	specificity	specificity	NOUN
fnp-4682	283	20	for	for	ADP
fnp-4682	283	21	the	the	DET
fnp-4682	283	22	ultimate	ultimate	ADJ
fnp-4682	283	23	diagnosis	diagnosis	NOUN
fnp-4682	283	24	of	of	ADP
fnp-4682	283	25	motor	motor	NOUN
fnp-4682	283	26	neuropathy	neuropathy	ADJ
fnp-4682	283	27	)	)	PUNCT
fnp-4682	283	28	,	,	PUNCT
fnp-4682	283	29	the	the	DET
fnp-4682	283	30	specificity	specificity	NOUN
fnp-4682	283	31	of	of	ADP
fnp-4682	283	32	pathologic	pathologic	ADJ
fnp-4682	283	33	mnd	mnd	NOUN
fnp-4682	283	34	pattern	pattern	NOUN
fnp-4682	283	35	for	for	ADP
fnp-4682	283	36	the	the	DET
fnp-4682	283	37	final	final	ADJ
fnp-4682	283	38	diagnosis	diagnosis	NOUN
fnp-4682	283	39	of	of	ADP
fnp-4682	283	40	als	als	NOUN
fnp-4682	283	41	in	in	ADP
fnp-4682	283	42	that	that	DET
fnp-4682	283	43	patient	patient	ADJ
fnp-4682	283	44	cohort	cohort	NOUN
fnp-4682	283	45	was	be	AUX
fnp-4682	283	46	66.6	66.6	NUM
fnp-4682	283	47	%	%	NOUN
fnp-4682	283	48	,	,	PUNCT
fnp-4682	283	49	while	while	SCONJ
fnp-4682	283	50	its	its	PRON
fnp-4682	283	51	sensitivity	sensitivity	NOUN
fnp-4682	283	52	was	be	AUX
fnp-4682	283	53	78.9	78.9	NUM
fnp-4682	283	54	%	%	NOUN
fnp-4682	283	55	.	.	PUNCT
fnp-4682	284	1	(	(	PUNCT
fnp-4682	284	2	interestingly	interestingly	ADV
fnp-4682	284	3	,	,	PUNCT
fnp-4682	284	4	the	the	DET
fnp-4682	284	5	degree	degree	NOUN
fnp-4682	284	6	of	of	ADP
fnp-4682	284	7	axon	axon	NOUN
fnp-4682	284	8	loss	loss	NOUN
fnp-4682	284	9	in	in	ADP
fnp-4682	284	10	als	als	NOUN
fnp-4682	284	11	cases	case	NOUN
fnp-4682	284	12	was	be	AUX
fnp-4682	284	13	predictive	predictive	ADJ
fnp-4682	284	14	of	of	ADP
fnp-4682	284	15	the	the	DET
fnp-4682	284	16	overall	overall	ADJ
fnp-4682	284	17	and	and	CCONJ
fnp-4682	284	18	post	post	ADJ
fnp-4682	284	19	-	-	ADJ
fnp-4682	284	20	biopsy	biopsy	ADJ
fnp-4682	284	21	survival	survival	NOUN
fnp-4682	284	22	length	length	NOUN
fnp-4682	284	23	.	.	PUNCT
fnp-4682	284	24	)	)	PUNCT
fnp-4682	285	1	in	in	ADP
fnp-4682	285	2	the	the	DET
fnp-4682	285	3	second	second	ADJ
fnp-4682	285	4	part	part	NOUN
fnp-4682	285	5	of	of	ADP
fnp-4682	285	6	the	the	DET
fnp-4682	285	7	study	study	NOUN
fnp-4682	285	8	,	,	PUNCT
fnp-4682	285	9	immunohistochemistry	immunohistochemistry	NOUN
fnp-4682	285	10	with	with	ADP
fnp-4682	285	11	polyclonal	polyclonal	ADJ
fnp-4682	285	12	anti	anti	ADJ
fnp-4682	285	13	-	-	ADJ
fnp-4682	285	14	tdp-43	tdp-43	ADJ
fnp-4682	285	15	and	and	CCONJ
fnp-4682	285	16	anti	anti	ADJ
fnp-4682	285	17	-	-	ADJ
fnp-4682	285	18	p(s409/410)tdp-43	p(s409/410)tdp-43	ADJ
fnp-4682	285	19	antibodies	antibody	NOUN
fnp-4682	285	20	was	be	AUX
fnp-4682	285	21	performed	perform	VERB
fnp-4682	285	22	on	on	ADP
fnp-4682	285	23	biopsies	biopsy	NOUN
fnp-4682	285	24	from	from	ADP
fnp-4682	285	25	80	80	NUM
fnp-4682	285	26	patients	patient	NOUN
fnp-4682	285	27	for	for	ADP
fnp-4682	285	28	which	which	PRON
fnp-4682	285	29	sufficient	sufficient	ADJ
fnp-4682	285	30	archival	archival	NOUN
fnp-4682	285	31	tissue	tissue	NOUN
fnp-4682	285	32	was	be	AUX
fnp-4682	285	33	available	available	ADJ
fnp-4682	285	34	;	;	PUNCT
fnp-4682	285	35	in	in	ADP
fnp-4682	285	36	this	this	DET
fnp-4682	285	37	subcohort	subcohort	NOUN
fnp-4682	285	38	,	,	PUNCT
fnp-4682	285	39	57	57	NUM
fnp-4682	285	40	patients	patient	NOUN
fnp-4682	285	41	(	(	PUNCT
fnp-4682	285	42	71.3	71.3	NUM
fnp-4682	285	43	%	%	NOUN
fnp-4682	285	44	)	)	PUNCT
fnp-4682	285	45	were	be	AUX
fnp-4682	285	46	ultimately	ultimately	ADV
fnp-4682	285	47	diagnosed	diagnose	VERB
fnp-4682	285	48	with	with	ADP
fnp-4682	285	49	als	al	NOUN
fnp-4682	285	50	.	.	PUNCT
fnp-4682	286	1	accumulation	accumulation	NOUN
fnp-4682	286	2	of	of	ADP
fnp-4682	286	3	tdp-43	tdp-43	PROPN
fnp-4682	286	4	in	in	ADP
fnp-4682	286	5	myelinated	myelinated	ADJ
fnp-4682	286	6	axons	axon	NOUN
fnp-4682	286	7	and	and	CCONJ
fnp-4682	286	8	sc	sc	NOUN
fnp-4682	286	9	cytoplasm	cytoplasm	NOUN
fnp-4682	286	10	was	be	AUX
fnp-4682	286	11	more	more	ADV
fnp-4682	286	12	commonly	commonly	ADV
fnp-4682	286	13	detected	detect	VERB
fnp-4682	286	14	in	in	ADP
fnp-4682	286	15	als	als	NOUN
fnp-4682	286	16	patients	patient	NOUN
fnp-4682	286	17	than	than	ADP
fnp-4682	286	18	in	in	ADP
fnp-4682	286	19	non	non	ADJ
fnp-4682	286	20	-	-	ADJ
fnp-4682	286	21	als	als	ADJ
fnp-4682	286	22	patients	patient	NOUN
fnp-4682	286	23	,	,	PUNCT
fnp-4682	286	24	but	but	CCONJ
fnp-4682	286	25	this	this	DET
fnp-4682	286	26	difference	difference	NOUN
fnp-4682	286	27	was	be	AUX
fnp-4682	286	28	statistically	statistically	ADV
fnp-4682	286	29	significant	significant	ADJ
fnp-4682	286	30	only	only	ADV
fnp-4682	286	31	when	when	SCONJ
fnp-4682	286	32	anti	anti	ADJ
fnp-4682	286	33	-	-	ADJ
fnp-4682	286	34	ptdp-43	ptdp-43	ADJ
fnp-4682	286	35	antibodies	antibody	NOUN
fnp-4682	286	36	were	be	AUX
fnp-4682	286	37	used	use	VERB
fnp-4682	286	38	;	;	PUNCT
fnp-4682	286	39	overall	overall	ADV
fnp-4682	286	40	,	,	PUNCT
fnp-4682	286	41	the	the	DET
fnp-4682	286	42	presence	presence	NOUN
fnp-4682	286	43	of	of	ADP
fnp-4682	286	44	ptdp-43	ptdp-43	PROPN
fnp-4682	286	45	aggregates	aggregate	NOUN
fnp-4682	286	46	had	have	VERB
fnp-4682	286	47	the	the	DET
fnp-4682	286	48	specificity	specificity	NOUN
fnp-4682	286	49	of	of	ADP
fnp-4682	286	50	65.2	65.2	NUM
fnp-4682	286	51	%	%	NOUN
fnp-4682	286	52	and	and	CCONJ
fnp-4682	286	53	sensitivity	sensitivity	NOUN
fnp-4682	286	54	of	of	ADP
fnp-4682	286	55	98.2	98.2	NUM
fnp-4682	286	56	%	%	NOUN
fnp-4682	286	57	for	for	ADP
fnp-4682	286	58	the	the	DET
fnp-4682	286	59	final	final	ADJ
fnp-4682	286	60	diagnosis	diagnosis	NOUN
fnp-4682	286	61	of	of	ADP
fnp-4682	286	62	als	al	NOUN
fnp-4682	286	63	.	.	PUNCT
fnp-4682	287	1	interestingly	interestingly	ADV
fnp-4682	287	2	,	,	PUNCT
fnp-4682	287	3	some	some	PRON
fnp-4682	287	4	of	of	ADP
fnp-4682	287	5	the	the	DET
fnp-4682	287	6	patients	patient	NOUN
fnp-4682	287	7	with	with	ADP
fnp-4682	287	8	a	a	DET
fnp-4682	287	9	false	false	ADJ
fnp-4682	287	10	-	-	PUNCT
fnp-4682	287	11	positive	positive	ADJ
fnp-4682	287	12	ptdp-43	ptdp-43	NOUN
fnp-4682	287	13	signal	signal	NOUN
fnp-4682	287	14	in	in	ADP
fnp-4682	287	15	their	their	PRON
fnp-4682	287	16	motor	motor	NOUN
fnp-4682	287	17	nerve	nerve	NOUN
fnp-4682	287	18	biopsies	biopsy	NOUN
fnp-4682	287	19	were	be	AUX
fnp-4682	287	20	ultimately	ultimately	ADV
fnp-4682	287	21	diagnosed	diagnose	VERB
fnp-4682	287	22	with	with	ADP
fnp-4682	287	23	inclusion	inclusion	NOUN
fnp-4682	287	24	body	body	NOUN
fnp-4682	287	25	myositis	myositis	NOUN
fnp-4682	287	26	or	or	CCONJ
fnp-4682	287	27	idiopathic	idiopathic	ADJ
fnp-4682	287	28	motor	motor	NOUN
fnp-4682	287	29	neuropathy	neuropathy	ADJ
fnp-4682	287	30	.	.	PUNCT
fnp-4682	288	1	while	while	SCONJ
fnp-4682	288	2	this	this	DET
fnp-4682	288	3	finding	finding	NOUN
fnp-4682	288	4	represents	represent	VERB
fnp-4682	288	5	a	a	DET
fnp-4682	288	6	limitation	limitation	NOUN
fnp-4682	288	7	from	from	ADP
fnp-4682	288	8	the	the	DET
fnp-4682	288	9	diagnostic	diagnostic	ADJ
fnp-4682	288	10	perspective	perspective	NOUN
fnp-4682	288	11	,	,	PUNCT
fnp-4682	288	12	it	it	PRON
fnp-4682	288	13	highlights	highlight	VERB
fnp-4682	288	14	the	the	DET
fnp-4682	288	15	mechanistic	mechanistic	ADJ
fnp-4682	288	16	connections	connection	NOUN
fnp-4682	288	17	between	between	ADP
fnp-4682	288	18	these	these	DET
fnp-4682	288	19	disorders	disorder	NOUN
fnp-4682	288	20	:	:	PUNCT
fnp-4682	288	21	multisystem	multisystem	NOUN
fnp-4682	288	22	proteinopathies	proteinopathie	NOUN
fnp-4682	288	23	,	,	PUNCT
fnp-4682	288	24	which	which	PRON
fnp-4682	288	25	clinically	clinically	ADV
fnp-4682	288	26	manifest	manifest	VERB
fnp-4682	288	27	as	as	ADP
fnp-4682	288	28	one	one	NUM
fnp-4682	288	29	or	or	CCONJ
fnp-4682	288	30	more	more	ADJ
fnp-4682	288	31	of	of	ADP
fnp-4682	288	32	these	these	DET
fnp-4682	288	33	diseases	disease	NOUN
fnp-4682	288	34	,	,	PUNCT
fnp-4682	288	35	have	have	AUX
fnp-4682	288	36	been	be	AUX
fnp-4682	288	37	etiologically	etiologically	ADV
fnp-4682	288	38	linked	link	VERB
fnp-4682	288	39	to	to	ADP
fnp-4682	288	40	impaired	impaired	ADJ
fnp-4682	288	41	biology	biology	NOUN
fnp-4682	288	42	of	of	ADP
fnp-4682	288	43	tdp-43	tdp-43	PROPN
fnp-4682	288	44	-	-	PUNCT
fnp-4682	288	45	containing	contain	VERB
fnp-4682	288	46	rna	rna	NOUN
fnp-4682	288	47	stress	stress	NOUN
fnp-4682	288	48	granules	granule	NOUN
fnp-4682	288	49	(	(	PUNCT
fnp-4682	288	50	korb	korb	PROPN
fnp-4682	288	51	et	et	PROPN
fnp-4682	288	52	al	al	PROPN
fnp-4682	288	53	.	.	PROPN
fnp-4682	288	54	,	,	PUNCT
fnp-4682	288	55	2021	2021	NUM
fnp-4682	288	56	)	)	PUNCT
fnp-4682	288	57	.	.	PUNCT
fnp-4682	289	1	interestingly	interestingly	ADV
fnp-4682	289	2	,	,	PUNCT
fnp-4682	289	3	axonal	axonal	ADJ
fnp-4682	289	4	ptdp-43	ptdp-43	PROPN
fnp-4682	289	5	aggregates	aggregate	NOUN
fnp-4682	289	6	were	be	AUX
fnp-4682	289	7	detected	detect	VERB
fnp-4682	289	8	in	in	ADP
fnp-4682	289	9	11	11	NUM
fnp-4682	289	10	of	of	ADP
fnp-4682	289	11	11	11	NUM
fnp-4682	289	12	als	als	NOUN
fnp-4682	289	13	cases	case	NOUN
fnp-4682	289	14	with	with	ADP
fnp-4682	289	15	normal	normal	ADJ
fnp-4682	289	16	(	(	PUNCT
fnp-4682	289	17	and	and	CCONJ
fnp-4682	289	18	therefore	therefore	ADV
fnp-4682	289	19	nondiagnostic	nondiagnostic	ADJ
fnp-4682	289	20	)	)	PUNCT
fnp-4682	289	21	motor	motor	NOUN
fnp-4682	289	22	nerve	nerve	NOUN
fnp-4682	289	23	biopsies	biopsy	NOUN
fnp-4682	289	24	,	,	PUNCT
fnp-4682	289	25	suggesting	suggest	VERB
fnp-4682	289	26	that	that	SCONJ
fnp-4682	289	27	ptdp-43	ptdp-43	ADJ
fnp-4682	289	28	accumulation	accumulation	NOUN
fnp-4682	289	29	is	be	AUX
fnp-4682	289	30	an	an	DET
fnp-4682	289	31	early	early	ADJ
fnp-4682	289	32	event	event	NOUN
fnp-4682	289	33	in	in	ADP
fnp-4682	289	34	the	the	DET
fnp-4682	289	35	disease	disease	NOUN
fnp-4682	289	36	progression	progression	NOUN
fnp-4682	289	37	that	that	PRON
fnp-4682	289	38	precedes	precede	VERB
fnp-4682	289	39	lmn	lmn	NOUN
fnp-4682	289	40	degeneration	degeneration	NOUN
fnp-4682	289	41	and	and	CCONJ
fnp-4682	289	42	axon	axon	NOUN
fnp-4682	289	43	loss	loss	NOUN
fnp-4682	289	44	.	.	PUNCT
fnp-4682	290	1	one	one	NUM
fnp-4682	290	2	limitation	limitation	NOUN
fnp-4682	290	3	of	of	ADP
fnp-4682	290	4	the	the	DET
fnp-4682	290	5	current	current	ADJ
fnp-4682	290	6	study	study	NOUN
fnp-4682	290	7	is	be	AUX
fnp-4682	290	8	that	that	SCONJ
fnp-4682	290	9	the	the	DET
fnp-4682	290	10	authors	author	NOUN
fnp-4682	290	11	did	do	AUX
fnp-4682	290	12	not	not	PART
fnp-4682	290	13	evaluate	evaluate	VERB
fnp-4682	290	14	whether	whether	SCONJ
fnp-4682	290	15	specificity	specificity	NOUN
fnp-4682	290	16	and	and	CCONJ
fnp-4682	290	17	sensitivity	sensitivity	NOUN
fnp-4682	290	18	of	of	ADP
fnp-4682	290	19	the	the	DET
fnp-4682	290	20	motor	motor	NOUN
fnp-4682	290	21	nerve	nerve	NOUN
fnp-4682	290	22	biopsy	biopsy	NOUN
fnp-4682	290	23	in	in	ADP
fnp-4682	290	24	the	the	DET
fnp-4682	290	25	als	als	NOUN
fnp-4682	290	26	diagnosis	diagnosis	NOUN
fnp-4682	290	27	could	could	AUX
fnp-4682	290	28	be	be	AUX
fnp-4682	290	29	improved	improve	VERB
fnp-4682	290	30	by	by	ADP
fnp-4682	290	31	combining	combine	VERB
fnp-4682	290	32	the	the	DET
fnp-4682	290	33	results	result	NOUN
fnp-4682	290	34	of	of	ADP
fnp-4682	290	35	standard	standard	ADJ
fnp-4682	290	36	histopathologic	histopathologic	ADJ
fnp-4682	290	37	analysis	analysis	NOUN
fnp-4682	290	38	with	with	ADP
fnp-4682	290	39	ptdp-43	ptdp-43	PROPN
fnp-4682	290	40	immunohistochemistry	immunohistochemistry	NOUN
fnp-4682	290	41	;	;	PUNCT
fnp-4682	290	42	this	this	DET
fnp-4682	290	43	important	important	ADJ
fnp-4682	290	44	question	question	NOUN
fnp-4682	290	45	should	should	AUX
fnp-4682	290	46	be	be	AUX
fnp-4682	290	47	assessed	assess	VERB
fnp-4682	290	48	in	in	ADP
fnp-4682	290	49	future	future	ADJ
fnp-4682	290	50	studies	study	NOUN
fnp-4682	290	51	from	from	ADP
fnp-4682	290	52	this	this	DET
fnp-4682	290	53	or	or	CCONJ
fnp-4682	290	54	other	other	ADJ
fnp-4682	290	55	research	research	NOUN
fnp-4682	290	56	groups	group	NOUN
fnp-4682	290	57	.	.	PUNCT
fnp-4682	291	1	kurashige	kurashige	PROPN
fnp-4682	291	2	et	et	PROPN
fnp-4682	291	3	al	al	PROPN
fnp-4682	291	4	.	.	PROPN
fnp-4682	292	1	approached	approach	VERB
fnp-4682	292	2	the	the	DET
fnp-4682	292	3	same	same	ADJ
fnp-4682	292	4	question	question	NOUN
fnp-4682	292	5	in	in	ADP
fnp-4682	292	6	a	a	DET
fnp-4682	292	7	slightly	slightly	ADV
fnp-4682	292	8	different	different	ADJ
fnp-4682	292	9	way	way	NOUN
fnp-4682	292	10	,	,	PUNCT
fnp-4682	292	11	by	by	ADP
fnp-4682	292	12	focusing	focus	VERB
fnp-4682	292	13	on	on	ADP
fnp-4682	292	14	ptdp-43	ptdp-43	ADJ
fnp-4682	292	15	accumulation	accumulation	NOUN
fnp-4682	292	16	in	in	ADP
fnp-4682	292	17	the	the	DET
fnp-4682	292	18	intramuscular	intramuscular	ADJ
fnp-4682	292	19	motor	motor	NOUN
fnp-4682	292	20	nerve	nerve	NOUN
fnp-4682	292	21	twigs	twig	NOUN
fnp-4682	292	22	(	(	PUNCT
fnp-4682	292	23	kurashige	kurashige	NOUN
fnp-4682	292	24	et	et	PROPN
fnp-4682	292	25	al	al	PROPN
fnp-4682	292	26	.	.	PROPN
fnp-4682	292	27	,	,	PUNCT
fnp-4682	292	28	2022	2022	NUM
fnp-4682	292	29	)	)	PUNCT
fnp-4682	292	30	.	.	PUNCT
fnp-4682	293	1	in	in	ADP
fnp-4682	293	2	the	the	DET
fnp-4682	293	3	first	first	ADJ
fnp-4682	293	4	part	part	NOUN
fnp-4682	293	5	of	of	ADP
fnp-4682	293	6	their	their	PRON
fnp-4682	293	7	investigation	investigation	NOUN
fnp-4682	293	8	,	,	PUNCT
fnp-4682	293	9	these	these	DET
fnp-4682	293	10	authors	author	NOUN
fnp-4682	293	11	performed	perform	VERB
fnp-4682	293	12	an	an	DET
fnp-4682	293	13	autopsy	autopsy	ADJ
fnp-4682	293	14	case	case	NOUN
fnp-4682	293	15	-	-	PUNCT
fnp-4682	293	16	control	control	NOUN
fnp-4682	293	17	study	study	NOUN
fnp-4682	293	18	that	that	PRON
fnp-4682	293	19	included	include	VERB
fnp-4682	293	20	10	10	NUM
fnp-4682	293	21	patients	patient	NOUN
fnp-4682	293	22	with	with	ADP
fnp-4682	293	23	autopsy	autopsy	NOUN
fnp-4682	293	24	-	-	PUNCT
fnp-4682	293	25	confirmed	confirm	VERB
fnp-4682	293	26	sporadic	sporadic	ADJ
fnp-4682	293	27	als	al	NOUN
fnp-4682	293	28	and	and	CCONJ
fnp-4682	293	29	12	12	NUM
fnp-4682	293	30	control	control	NOUN
fnp-4682	293	31	,	,	PUNCT
fnp-4682	293	32	non	non	ADJ
fnp-4682	293	33	-	-	ADJ
fnp-4682	293	34	als	als	NOUN
fnp-4682	293	35	patients	patient	NOUN
fnp-4682	293	36	;	;	PUNCT
fnp-4682	293	37	for	for	ADP
fnp-4682	293	38	each	each	DET
fnp-4682	293	39	case	case	NOUN
fnp-4682	293	40	,	,	PUNCT
fnp-4682	293	41	muscle	muscle	NOUN
fnp-4682	293	42	samples	sample	NOUN
fnp-4682	293	43	were	be	AUX
fnp-4682	293	44	obtained	obtain	VERB
fnp-4682	293	45	from	from	ADP
fnp-4682	293	46	the	the	DET
fnp-4682	293	47	tongue	tongue	NOUN
fnp-4682	293	48	,	,	PUNCT
fnp-4682	293	49	diaphragm	diaphragm	PROPN
fnp-4682	293	50	,	,	PUNCT
fnp-4682	293	51	biceps	bicep	NOUN
fnp-4682	293	52	brachii	brachii	NOUN
fnp-4682	293	53	,	,	PUNCT
fnp-4682	293	54	and	and	CCONJ
fnp-4682	293	55	rectus	rectus	PROPN
fnp-4682	293	56	femoris	femoris	NOUN
fnp-4682	293	57	.	.	PUNCT
fnp-4682	294	1	the	the	DET
fnp-4682	294	2	second	second	ADJ
fnp-4682	294	3	part	part	NOUN
fnp-4682	294	4	of	of	ADP
fnp-4682	294	5	the	the	DET
fnp-4682	294	6	project	project	NOUN
fnp-4682	294	7	was	be	AUX
fnp-4682	294	8	a	a	DET
fnp-4682	294	9	retrospective	retrospective	ADJ
fnp-4682	294	10	cohort	cohort	NOUN
fnp-4682	294	11	study	study	NOUN
fnp-4682	294	12	,	,	PUNCT
fnp-4682	294	13	which	which	PRON
fnp-4682	294	14	started	start	VERB
fnp-4682	294	15	by	by	ADP
fnp-4682	294	16	screening	screen	VERB
fnp-4682	294	17	450	450	NUM
fnp-4682	294	18	patients	patient	NOUN
fnp-4682	294	19	who	who	PRON
fnp-4682	294	20	underwent	undergo	VERB
fnp-4682	294	21	a	a	DET
fnp-4682	294	22	diagnostic	diagnostic	ADJ
fnp-4682	294	23	muscle	muscle	NOUN
fnp-4682	294	24	biopsy	biopsy	NOUN
fnp-4682	294	25	at	at	ADP
fnp-4682	294	26	the	the	DET
fnp-4682	294	27	authors	author	NOUN
fnp-4682	294	28	’	’	PART
fnp-4682	294	29	institutions	institution	NOUN
fnp-4682	294	30	between	between	ADP
fnp-4682	294	31	2004	2004	NUM
fnp-4682	294	32	and	and	CCONJ
fnp-4682	294	33	2019	2019	NUM
fnp-4682	294	34	;	;	PUNCT
fnp-4682	294	35	after	after	SCONJ
fnp-4682	294	36	all	all	DET
fnp-4682	294	37	patients	patient	NOUN
fnp-4682	294	38	with	with	ADP
fnp-4682	294	39	a	a	DET
fnp-4682	294	40	myopathy	myopathy	ADJ
fnp-4682	294	41	and	and	CCONJ
fnp-4682	294	42	patients	patient	NOUN
fnp-4682	294	43	with	with	ADP
fnp-4682	294	44	pathogenic	pathogenic	ADJ
fnp-4682	294	45	variants	variant	NOUN
fnp-4682	294	46	in	in	ADP
fnp-4682	294	47	the	the	DET
fnp-4682	294	48	als	als	NOUN
fnp-4682	294	49	-	-	PUNCT
fnp-4682	294	50	associated	associate	VERB
fnp-4682	294	51	genes	gene	NOUN
fnp-4682	294	52	were	be	AUX
fnp-4682	294	53	excluded	exclude	VERB
fnp-4682	294	54	,	,	PUNCT
fnp-4682	294	55	the	the	DET
fnp-4682	294	56	study	study	NOUN
fnp-4682	294	57	cohort	cohort	NOUN
fnp-4682	294	58	consisted	consist	VERB
fnp-4682	294	59	of	of	ADP
fnp-4682	294	60	114	114	NUM
fnp-4682	294	61	patients	patient	NOUN
fnp-4682	294	62	,	,	PUNCT
fnp-4682	294	63	71	71	NUM
fnp-4682	294	64	of	of	ADP
fnp-4682	294	65	whom	whom	PRON
fnp-4682	294	66	had	have	VERB
fnp-4682	294	67	biopsies	biopsy	NOUN
fnp-4682	294	68	that	that	PRON
fnp-4682	294	69	included	include	VERB
fnp-4682	294	70	intramuscular	intramuscular	ADJ
fnp-4682	294	71	nerve	nerve	NOUN
fnp-4682	294	72	twigs	twig	NOUN
fnp-4682	294	73	.	.	PUNCT
fnp-4682	295	1	all	all	DET
fnp-4682	295	2	study	study	NOUN
fnp-4682	295	3	samples	sample	NOUN
fnp-4682	295	4	were	be	AUX
fnp-4682	295	5	stained	stain	VERB
fnp-4682	295	6	with	with	ADP
fnp-4682	295	7	both	both	CCONJ
fnp-4682	295	8	polyclonal	polyclonal	ADJ
fnp-4682	295	9	and	and	CCONJ
fnp-4682	295	10	monoclonal	monoclonal	NOUN
fnp-4682	295	11	anti	anti	ADJ
fnp-4682	295	12	-	-	ADJ
fnp-4682	295	13	p(s409/410)tdp-43	p(s409/410)tdp-43	ADJ
fnp-4682	295	14	antibodies	antibody	NOUN
fnp-4682	295	15	,	,	PUNCT
fnp-4682	295	16	which	which	PRON
fnp-4682	295	17	gave	give	VERB
fnp-4682	295	18	identical	identical	ADJ
fnp-4682	295	19	results	result	NOUN
fnp-4682	295	20	.	.	PUNCT
fnp-4682	296	1	in	in	ADP
fnp-4682	296	2	autopsy	autopsy	ADJ
fnp-4682	296	3	cases	case	NOUN
fnp-4682	296	4	,	,	PUNCT
fnp-4682	296	5	axonal	axonal	ADJ
fnp-4682	296	6	ptdp-43	ptdp-43	ADJ
fnp-4682	296	7	-	-	PUNCT
fnp-4682	296	8	positive	positive	ADJ
fnp-4682	296	9	aggregates	aggregate	NOUN
fnp-4682	296	10	(	(	PUNCT
fnp-4682	296	11	but	but	CCONJ
fnp-4682	296	12	no	no	DET
fnp-4682	296	13	fus-	fus-	ADJ
fnp-4682	296	14	,	,	PUNCT
fnp-4682	296	15	p62-	p62-	ADJ
fnp-4682	296	16	,	,	PUNCT
fnp-4682	296	17	or	or	CCONJ
fnp-4682	296	18	ubiquitin	ubiquitin	ADJ
fnp-4682	296	19	-	-	PUNCT
fnp-4682	296	20	positive	positive	ADJ
fnp-4682	296	21	aggregates	aggregate	NOUN
fnp-4682	296	22	)	)	PUNCT
fnp-4682	296	23	were	be	AUX
fnp-4682	296	24	detected	detect	VERB
fnp-4682	296	25	in	in	ADP
fnp-4682	296	26	all	all	DET
fnp-4682	296	27	als	als	NOUN
fnp-4682	296	28	patients	patient	NOUN
fnp-4682	296	29	but	but	CCONJ
fnp-4682	296	30	not	not	PART
fnp-4682	296	31	in	in	ADP
fnp-4682	296	32	any	any	PRON
fnp-4682	296	33	of	of	ADP
fnp-4682	296	34	the	the	DET
fnp-4682	296	35	controls	control	NOUN
fnp-4682	296	36	(	(	PUNCT
fnp-4682	296	37	fig	fig	NOUN
fnp-4682	296	38	.	.	PUNCT
fnp-4682	297	1	8)	8)	NUM
fnp-4682	297	2	;	;	PUNCT
fnp-4682	297	3	~50	~50	NUM
fnp-4682	297	4	%	%	NOUN
fnp-4682	297	5	of	of	ADP
fnp-4682	297	6	nerve	nerve	NOUN
fnp-4682	297	7	twigs	twig	NOUN
fnp-4682	297	8	were	be	AUX
fnp-4682	297	9	involved	involve	VERB
fnp-4682	297	10	in	in	ADP
fnp-4682	297	11	any	any	DET
fnp-4682	297	12	given	give	VERB
fnp-4682	297	13	case	case	NOUN
fnp-4682	297	14	,	,	PUNCT
fnp-4682	297	15	with	with	ADP
fnp-4682	297	16	no	no	DET
fnp-4682	297	17	significant	significant	ADJ
fnp-4682	297	18	differences	difference	NOUN
fnp-4682	297	19	among	among	ADP
fnp-4682	297	20	the	the	DET
fnp-4682	297	21	four	four	NUM
fnp-4682	297	22	sampled	sample	VERB
fnp-4682	297	23	muscle	muscle	NOUN
fnp-4682	297	24	groups	group	NOUN
fnp-4682	297	25	.	.	PUNCT
fnp-4682	298	1	in	in	ADP
fnp-4682	298	2	the	the	DET
fnp-4682	298	3	biopsy	biopsy	NOUN
fnp-4682	298	4	portion	portion	NOUN
fnp-4682	298	5	of	of	ADP
fnp-4682	298	6	the	the	DET
fnp-4682	298	7	study	study	NOUN
fnp-4682	298	8	,	,	PUNCT
fnp-4682	298	9	33	33	NUM
fnp-4682	298	10	of	of	ADP
fnp-4682	298	11	71	71	NUM
fnp-4682	298	12	cases	case	NOUN
fnp-4682	298	13	with	with	ADP
fnp-4682	298	14	intramuscular	intramuscular	ADJ
fnp-4682	298	15	nerve	nerve	NOUN
fnp-4682	298	16	twigs	twig	NOUN
fnp-4682	298	17	(	(	PUNCT
fnp-4682	298	18	46.5	46.5	NUM
fnp-4682	298	19	%	%	NOUN
fnp-4682	298	20	)	)	PUNCT
fnp-4682	298	21	showed	show	VERB
fnp-4682	298	22	axonal	axonal	ADJ
fnp-4682	298	23	ptdp-43	ptdp-43	ADJ
fnp-4682	298	24	-	-	PUNCT
fnp-4682	298	25	positive	positive	ADJ
fnp-4682	298	26	aggregates	aggregate	NOUN
fnp-4682	298	27	;	;	PUNCT
fnp-4682	298	28	all	all	DET
fnp-4682	298	29	these	these	DET
fnp-4682	298	30	patients	patient	NOUN
fnp-4682	298	31	were	be	AUX
fnp-4682	298	32	ultimately	ultimately	ADV
fnp-4682	298	33	diagnosed	diagnose	VERB
fnp-4682	298	34	with	with	ADP
fnp-4682	298	35	als	als	NOUN
fnp-4682	298	36	(	(	PUNCT
fnp-4682	298	37	9	9	NUM
fnp-4682	298	38	with	with	ADP
fnp-4682	298	39	the	the	DET
fnp-4682	298	40	lmn	lmn	NOUN
fnp-4682	298	41	-	-	PUNCT
fnp-4682	298	42	predominant	predominant	ADJ
fnp-4682	298	43	form	form	NOUN
fnp-4682	298	44	)	)	PUNCT
fnp-4682	298	45	,	,	PUNCT
fnp-4682	298	46	while	while	SCONJ
fnp-4682	298	47	none	none	NOUN
fnp-4682	298	48	of	of	ADP
fnp-4682	298	49	38	38	NUM
fnp-4682	298	50	ptdp-43	ptdp-43	ADJ
fnp-4682	298	51	-	-	PUNCT
fnp-4682	298	52	negative	negative	ADJ
fnp-4682	298	53	patients	patient	NOUN
fnp-4682	298	54	received	receive	VERB
fnp-4682	298	55	the	the	DET
fnp-4682	298	56	als	als	NOUN
fnp-4682	298	57	diagnosis	diagnosis	NOUN
fnp-4682	298	58	,	,	PUNCT
fnp-4682	298	59	and	and	CCONJ
fnp-4682	298	60	were	be	AUX
fnp-4682	298	61	instead	instead	ADV
fnp-4682	298	62	ultimately	ultimately	ADV
fnp-4682	298	63	diagnosed	diagnose	VERB
fnp-4682	298	64	with	with	ADP
fnp-4682	298	65	other	other	ADJ
fnp-4682	298	66	mnds	mnd	NOUN
fnp-4682	298	67	or	or	CCONJ
fnp-4682	298	68	neuropathies	neuropathy	NOUN
fnp-4682	298	69	.	.	PUNCT
fnp-4682	299	1	(	(	PUNCT
fnp-4682	299	2	interestingly	interestingly	ADV
fnp-4682	299	3	,	,	PUNCT
fnp-4682	299	4	only	only	ADV
fnp-4682	299	5	4	4	NUM
fnp-4682	299	6	of	of	ADP
fnp-4682	299	7	the	the	DET
fnp-4682	299	8	114	114	NUM
fnp-4682	299	9	patients	patient	NOUN
fnp-4682	299	10	in	in	ADP
fnp-4682	299	11	the	the	DET
fnp-4682	299	12	muscle	muscle	NOUN
fnp-4682	299	13	biopsy	biopsy	NOUN
fnp-4682	299	14	cohort	cohort	NOUN
fnp-4682	299	15	were	be	AUX
fnp-4682	299	16	clinically	clinically	ADV
fnp-4682	299	17	suspected	suspect	VERB
fnp-4682	299	18	of	of	ADP
fnp-4682	299	19	having	have	VERB
fnp-4682	299	20	als	als	NOUN
fnp-4682	299	21	prior	prior	ADV
fnp-4682	299	22	to	to	ADP
fnp-4682	299	23	the	the	DET
fnp-4682	299	24	biopsy	biopsy	NOUN
fnp-4682	299	25	.	.	PUNCT
fnp-4682	299	26	)	)	PUNCT
fnp-4682	300	1	figure	figure	VERB
fnp-4682	300	2	8	8	NUM
fnp-4682	300	3	.	.	PUNCT
fnp-4682	300	4	axonal	axonal	ADJ
fnp-4682	300	5	ptdp-43	ptdp-43	PROPN
fnp-4682	300	6	–	–	PUNCT
fnp-4682	300	7	positive	positive	ADJ
fnp-4682	300	8	accumulations	accumulation	NOUN
fnp-4682	300	9	in	in	ADP
fnp-4682	300	10	intramuscular	intramuscular	ADJ
fnp-4682	300	11	nerve	nerve	NOUN
fnp-4682	300	12	bundles	bundle	NOUN
fnp-4682	300	13	of	of	ADP
fnp-4682	300	14	skeletal	skeletal	ADJ
fnp-4682	300	15	muscle	muscle	NOUN
fnp-4682	300	16	in	in	ADP
fnp-4682	300	17	the	the	DET
fnp-4682	300	18	postmortem	postmortem	NOUN
fnp-4682	300	19	case	case	NOUN
fnp-4682	300	20	-	-	PUNCT
fnp-4682	300	21	control	control	NOUN
fnp-4682	300	22	study	study	NOUN
fnp-4682	300	23	.	.	PUNCT
fnp-4682	301	1	(	(	PUNCT
fnp-4682	301	2	a	a	PRON
fnp-4682	301	3	and	and	CCONJ
fnp-4682	301	4	d	d	NOUN
fnp-4682	301	5	)	)	PUNCT
fnp-4682	301	6	h&e	h&e	NOUN
fnp-4682	301	7	-	-	PUNCT
fnp-4682	301	8	staining	stain	VERB
fnp-4682	301	9	in	in	ADP
fnp-4682	301	10	axons	axon	NOUN
fnp-4682	301	11	of	of	ADP
fnp-4682	301	12	intramuscular	intramuscular	ADJ
fnp-4682	301	13	nerve	nerve	NOUN
fnp-4682	301	14	bundles	bundle	NOUN
fnp-4682	301	15	showed	show	VERB
fnp-4682	301	16	no	no	DET
fnp-4682	301	17	differences	difference	NOUN
fnp-4682	301	18	between	between	ADP
fnp-4682	301	19	patients	patient	NOUN
fnp-4682	301	20	with	with	ADP
fnp-4682	301	21	amyotrophic	amyotrophic	ADJ
fnp-4682	301	22	lateral	lateral	ADJ
fnp-4682	301	23	sclerosis	sclerosis	NOUN
fnp-4682	301	24	(	(	PUNCT
fnp-4682	301	25	als	als	NOUN
fnp-4682	301	26	)	)	PUNCT
fnp-4682	301	27	and	and	CCONJ
fnp-4682	301	28	those	those	PRON
fnp-4682	301	29	without	without	ADP
fnp-4682	301	30	als	als	NOUN
fnp-4682	301	31	except	except	SCONJ
fnp-4682	301	32	for	for	ADP
fnp-4682	301	33	the	the	DET
fnp-4682	301	34	density	density	NOUN
fnp-4682	301	35	of	of	ADP
fnp-4682	301	36	intramuscular	intramuscular	ADJ
fnp-4682	301	37	nerves	nerve	NOUN
fnp-4682	301	38	(	(	PUNCT
fnp-4682	301	39	original	original	ADJ
fnp-4682	301	40	magnification	magnification	NOUN
fnp-4682	301	41	:	:	PUNCT
fnp-4682	301	42	a	a	PRON
fnp-4682	301	43	,	,	PUNCT
fnp-4682	301	44	×40	×40	PROPN
fnp-4682	301	45	;	;	PUNCT
fnp-4682	301	46	d	d	NOUN
fnp-4682	301	47	,	,	PUNCT
fnp-4682	301	48	×60	×60	NUM
fnp-4682	301	49	)	)	PUNCT
fnp-4682	301	50	.	.	PUNCT
fnp-4682	302	1	(	(	PUNCT
fnp-4682	302	2	b	b	X
fnp-4682	302	3	)	)	PUNCT
fnp-4682	302	4	immunohistochemical	immunohistochemical	ADJ
fnp-4682	302	5	analysis	analysis	NOUN
fnp-4682	302	6	with	with	ADP
fnp-4682	302	7	mouse	mouse	NOUN
fnp-4682	302	8	monoclonal	monoclonal	NOUN
fnp-4682	302	9	ptdp-43	ptdp-43	NOUN
fnp-4682	302	10	–	–	PUNCT
fnp-4682	302	11	positive	positive	ADJ
fnp-4682	302	12	accumulations	accumulation	NOUN
fnp-4682	302	13	in	in	ADP
fnp-4682	302	14	intramuscular	intramuscular	ADJ
fnp-4682	302	15	nerve	nerve	NOUN
fnp-4682	302	16	bundles	bundle	NOUN
fnp-4682	302	17	(	(	PUNCT
fnp-4682	302	18	arrowheads	arrowhead	NOUN
fnp-4682	302	19	)	)	PUNCT
fnp-4682	302	20	of	of	ADP
fnp-4682	302	21	patients	patient	NOUN
fnp-4682	302	22	with	with	ADP
fnp-4682	302	23	spontaneous	spontaneous	ADJ
fnp-4682	302	24	als	als	NOUN
fnp-4682	302	25	(	(	PUNCT
fnp-4682	302	26	sals	sal	NOUN
fnp-4682	302	27	)	)	PUNCT
fnp-4682	302	28	(	(	PUNCT
fnp-4682	302	29	original	original	ADJ
fnp-4682	302	30	magnification	magnification	NOUN
fnp-4682	302	31	,	,	PUNCT
fnp-4682	302	32	×40	×40	PROPN
fnp-4682	302	33	)	)	PUNCT
fnp-4682	302	34	.	.	PUNCT
fnp-4682	303	1	(	(	PUNCT
fnp-4682	303	2	e	e	X
fnp-4682	303	3	)	)	PUNCT
fnp-4682	303	4	immunostaining	immunostaine	VERB
fnp-4682	303	5	with	with	ADP
fnp-4682	303	6	mouse	mouse	NOUN
fnp-4682	303	7	monoclonal	monoclonal	NOUN
fnp-4682	303	8	antibody	antibody	NOUN
fnp-4682	303	9	against	against	ADP
fnp-4682	303	10	ptdp-43	ptdp-43	PROPN
fnp-4682	303	11	in	in	ADP
fnp-4682	303	12	patients	patient	NOUN
fnp-4682	303	13	with	with	ADP
fnp-4682	303	14	non	non	ADJ
fnp-4682	303	15	-	-	ADJ
fnp-4682	303	16	als	als	ADJ
fnp-4682	303	17	diseases	disease	NOUN
fnp-4682	303	18	did	do	AUX
fnp-4682	303	19	not	not	PART
fnp-4682	303	20	reveal	reveal	VERB
fnp-4682	303	21	any	any	DET
fnp-4682	303	22	abnormalities	abnormality	NOUN
fnp-4682	303	23	in	in	ADP
fnp-4682	303	24	intramuscular	intramuscular	ADJ
fnp-4682	303	25	nerve	nerve	NOUN
fnp-4682	303	26	bundles	bundle	NOUN
fnp-4682	303	27	(	(	PUNCT
fnp-4682	303	28	original	original	ADJ
fnp-4682	303	29	magnification	magnification	NOUN
fnp-4682	303	30	,	,	PUNCT
fnp-4682	303	31	×40	×40	PROPN
fnp-4682	303	32	)	)	PUNCT
fnp-4682	303	33	.	.	PUNCT
fnp-4682	304	1	(	(	PUNCT
fnp-4682	304	2	c	c	X
fnp-4682	304	3	)	)	PUNCT
fnp-4682	304	4	immunohistochemical	immunohistochemical	ADJ
fnp-4682	304	5	analysis	analysis	NOUN
fnp-4682	304	6	with	with	ADP
fnp-4682	304	7	rabbit	rabbit	NOUN
fnp-4682	304	8	polyclonal	polyclonal	ADJ
fnp-4682	304	9	ptdp-43	ptdp-43	ADJ
fnp-4682	304	10	antibody	antibody	NOUN
fnp-4682	304	11	also	also	ADV
fnp-4682	304	12	revealed	reveal	VERB
fnp-4682	304	13	ptdp-43	ptdp-43	PROPN
fnp-4682	304	14	–	–	PUNCT
fnp-4682	304	15	positive	positive	ADJ
fnp-4682	304	16	accumulations	accumulation	NOUN
fnp-4682	304	17	in	in	ADP
fnp-4682	304	18	intramuscular	intramuscular	ADJ
fnp-4682	304	19	nerve	nerve	NOUN
fnp-4682	304	20	bundles	bundle	NOUN
fnp-4682	304	21	(	(	PUNCT
fnp-4682	304	22	arrowheads	arrowhead	NOUN
fnp-4682	304	23	)	)	PUNCT
fnp-4682	304	24	of	of	ADP
fnp-4682	304	25	patients	patient	NOUN
fnp-4682	304	26	with	with	ADP
fnp-4682	304	27	sals	sal	NOUN
fnp-4682	304	28	(	(	PUNCT
fnp-4682	304	29	original	original	ADJ
fnp-4682	304	30	magnification	magnification	NOUN
fnp-4682	304	31	,	,	PUNCT
fnp-4682	304	32	×60	×60	NUM
fnp-4682	304	33	)	)	PUNCT
fnp-4682	304	34	.	.	PUNCT
fnp-4682	305	1	(	(	PUNCT
fnp-4682	305	2	f	f	X
fnp-4682	305	3	)	)	PUNCT
fnp-4682	305	4	immunostaining	immunostaine	VERB
fnp-4682	305	5	with	with	ADP
fnp-4682	305	6	rabbit	rabbit	NOUN
fnp-4682	305	7	polyclonal	polyclonal	ADJ
fnp-4682	305	8	antibody	antibody	NOUN
fnp-4682	305	9	against	against	ADP
fnp-4682	305	10	ptdp-43	ptdp-43	PROPN
fnp-4682	305	11	in	in	ADP
fnp-4682	305	12	patients	patient	NOUN
fnp-4682	305	13	with	with	ADP
fnp-4682	305	14	non	non	ADJ
fnp-4682	305	15	-	-	ADJ
fnp-4682	305	16	als	als	ADJ
fnp-4682	305	17	diseases	disease	NOUN
fnp-4682	305	18	did	do	AUX
fnp-4682	305	19	not	not	PART
fnp-4682	305	20	reveal	reveal	VERB
fnp-4682	305	21	any	any	DET
fnp-4682	305	22	abnormalities	abnormality	NOUN
fnp-4682	305	23	in	in	ADP
fnp-4682	305	24	intramuscular	intramuscular	ADJ
fnp-4682	305	25	nerve	nerve	NOUN
fnp-4682	305	26	bundles	bundle	NOUN
fnp-4682	305	27	(	(	PUNCT
fnp-4682	305	28	original	original	ADJ
fnp-4682	305	29	magnification	magnification	NOUN
fnp-4682	305	30	,	,	PUNCT
fnp-4682	305	31	×40	×40	PROPN
fnp-4682	305	32	)	)	PUNCT
fnp-4682	305	33	.	.	PUNCT
fnp-4682	306	1	[	[	X
fnp-4682	306	2	this	this	DET
fnp-4682	306	3	figure	figure	NOUN
fnp-4682	306	4	and	and	CCONJ
fnp-4682	306	5	its	its	PRON
fnp-4682	306	6	legend	legend	NOUN
fnp-4682	306	7	were	be	AUX
fnp-4682	306	8	adopted	adopt	VERB
fnp-4682	306	9	from	from	ADP
fnp-4682	306	10	figure	figure	NOUN
fnp-4682	306	11	2	2	NUM
fnp-4682	306	12	in	in	ADP
fnp-4682	306	13	(	(	PUNCT
fnp-4682	306	14	kurashige	kurashige	NOUN
fnp-4682	306	15	et	et	PROPN
fnp-4682	306	16	al	al	PROPN
fnp-4682	306	17	.	.	PROPN
fnp-4682	306	18	,	,	PUNCT
fnp-4682	306	19	2022	2022	NUM
fnp-4682	306	20	)	)	PUNCT
fnp-4682	306	21	;	;	PUNCT
fnp-4682	306	22	this	this	DET
fnp-4682	306	23	use	use	NOUN
fnp-4682	306	24	is	be	AUX
fnp-4682	306	25	permitted	permit	VERB
fnp-4682	306	26	under	under	ADP
fnp-4682	306	27	the	the	DET
fnp-4682	306	28	creative	creative	ADJ
fnp-4682	306	29	commons	common	NOUN
fnp-4682	306	30	attribution	attribution	NOUN
fnp-4682	306	31	4.0	4.0	NUM
fnp-4682	306	32	cc	cc	NOUN
fnp-4682	306	33	-	-	PUNCT
fnp-4682	306	34	by	by	ADP
fnp-4682	306	35	international	international	ADJ
fnp-4682	306	36	license	license	NOUN
fnp-4682	306	37	.	.	PUNCT
fnp-4682	307	1	]	]	PUNCT
fnp-4682	307	2	taken	take	VERB
fnp-4682	307	3	together	together	ADV
fnp-4682	307	4	,	,	PUNCT
fnp-4682	307	5	these	these	DET
fnp-4682	307	6	two	two	NUM
fnp-4682	307	7	studies	study	NOUN
fnp-4682	307	8	provide	provide	VERB
fnp-4682	307	9	compelling	compelling	ADJ
fnp-4682	307	10	evidence	evidence	NOUN
fnp-4682	307	11	that	that	SCONJ
fnp-4682	307	12	immunohistochemical	immunohistochemical	ADJ
fnp-4682	307	13	detection	detection	NOUN
fnp-4682	307	14	of	of	ADP
fnp-4682	307	15	ptdp-43	ptdp-43	ADJ
fnp-4682	307	16	-	-	ADJ
fnp-4682	307	17	positive	positive	ADJ
fnp-4682	307	18	protein	protein	NOUN
fnp-4682	307	19	aggregates	aggregate	NOUN
fnp-4682	307	20	in	in	ADP
fnp-4682	307	21	motor	motor	NOUN
fnp-4682	307	22	axons	axon	NOUN
fnp-4682	307	23	is	be	AUX
fnp-4682	307	24	a	a	DET
fnp-4682	307	25	useful	useful	ADJ
fnp-4682	307	26	diagnostic	diagnostic	ADJ
fnp-4682	307	27	marker	marker	NOUN
fnp-4682	307	28	of	of	ADP
fnp-4682	307	29	als	al	NOUN
fnp-4682	307	30	.	.	PUNCT
fnp-4682	308	1	while	while	SCONJ
fnp-4682	308	2	the	the	DET
fnp-4682	308	3	results	result	NOUN
fnp-4682	308	4	of	of	ADP
fnp-4682	308	5	both	both	DET
fnp-4682	308	6	studies	study	NOUN
fnp-4682	308	7	need	need	VERB
fnp-4682	308	8	to	to	PART
fnp-4682	308	9	be	be	AUX
fnp-4682	308	10	replicated	replicate	VERB
fnp-4682	308	11	by	by	ADP
fnp-4682	308	12	other	other	ADJ
fnp-4682	308	13	researchers	researcher	NOUN
fnp-4682	308	14	,	,	PUNCT
fnp-4682	308	15	these	these	DET
fnp-4682	308	16	findings	finding	NOUN
fnp-4682	308	17	suggest	suggest	VERB
fnp-4682	308	18	that	that	SCONJ
fnp-4682	308	19	muscle	muscle	NOUN
fnp-4682	308	20	biopsy	biopsy	NOUN
fnp-4682	308	21	evaluation	evaluation	NOUN
fnp-4682	308	22	is	be	AUX
fnp-4682	308	23	a	a	DET
fnp-4682	308	24	particularly	particularly	ADV
fnp-4682	308	25	promising	promising	ADJ
fnp-4682	308	26	diagnostic	diagnostic	ADJ
fnp-4682	308	27	approach	approach	NOUN
fnp-4682	308	28	:	:	PUNCT
fnp-4682	308	29	not	not	PART
fnp-4682	308	30	only	only	ADV
fnp-4682	308	31	are	be	AUX
fnp-4682	308	32	muscle	muscle	NOUN
fnp-4682	308	33	biopsies	biopsy	NOUN
fnp-4682	308	34	easier	easy	ADJ
fnp-4682	308	35	to	to	PART
fnp-4682	308	36	do	do	VERB
fnp-4682	308	37	and	and	CCONJ
fnp-4682	308	38	have	have	VERB
fnp-4682	308	39	lower	low	ADJ
fnp-4682	308	40	morbidity	morbidity	NOUN
fnp-4682	308	41	than	than	ADP
fnp-4682	308	42	motor	motor	NOUN
fnp-4682	308	43	nerve	nerve	NOUN
fnp-4682	308	44	biopsies	biopsy	NOUN
fnp-4682	308	45	,	,	PUNCT
fnp-4682	308	46	they	they	PRON
fnp-4682	308	47	also	also	ADV
fnp-4682	308	48	showed	show	VERB
fnp-4682	308	49	higher	high	ADJ
fnp-4682	308	50	overall	overall	ADJ
fnp-4682	308	51	specificity	specificity	NOUN
fnp-4682	308	52	and	and	CCONJ
fnp-4682	308	53	sensitivity	sensitivity	NOUN
fnp-4682	308	54	than	than	ADP
fnp-4682	308	55	nerve	nerve	NOUN
fnp-4682	308	56	biopsies	biopsy	NOUN
fnp-4682	308	57	(	(	PUNCT
fnp-4682	308	58	perhaps	perhaps	ADV
fnp-4682	308	59	because	because	SCONJ
fnp-4682	308	60	potentially	potentially	ADV
fnp-4682	308	61	confounding	confound	VERB
fnp-4682	308	62	myopathic	myopathic	ADJ
fnp-4682	308	63	biopsies	biopsy	NOUN
fnp-4682	308	64	could	could	AUX
fnp-4682	308	65	easily	easily	ADV
fnp-4682	308	66	be	be	AUX
fnp-4682	308	67	excluded	exclude	VERB
fnp-4682	308	68	)	)	PUNCT
fnp-4682	308	69	.	.	PUNCT
fnp-4682	309	1	of	of	ADP
fnp-4682	309	2	course	course	NOUN
fnp-4682	309	3	,	,	PUNCT
fnp-4682	309	4	the	the	DET
fnp-4682	309	5	utility	utility	NOUN
fnp-4682	309	6	of	of	ADP
fnp-4682	309	7	muscle	muscle	NOUN
fnp-4682	309	8	biopsies	biopsy	NOUN
fnp-4682	309	9	for	for	ADP
fnp-4682	309	10	als	als	NOUN
fnp-4682	309	11	diagnosis	diagnosis	NOUN
fnp-4682	309	12	is	be	AUX
fnp-4682	309	13	limited	limit	VERB
fnp-4682	309	14	by	by	ADP
fnp-4682	309	15	the	the	DET
fnp-4682	309	16	lack	lack	NOUN
fnp-4682	309	17	of	of	ADP
fnp-4682	309	18	intramuscular	intramuscular	ADJ
fnp-4682	309	19	nerve	nerve	NOUN
fnp-4682	309	20	twigs	twig	NOUN
fnp-4682	309	21	in	in	ADP
fnp-4682	309	22	many	many	ADJ
fnp-4682	309	23	specimens	specimen	NOUN
fnp-4682	309	24	(	(	PUNCT
fnp-4682	309	25	~40	~40	ADV
fnp-4682	309	26	%	%	NOUN
fnp-4682	309	27	in	in	ADP
fnp-4682	309	28	this	this	DET
fnp-4682	309	29	study	study	NOUN
fnp-4682	309	30	cohort	cohort	NOUN
fnp-4682	309	31	)	)	PUNCT
fnp-4682	309	32	;	;	PUNCT
fnp-4682	309	33	obtaining	obtain	VERB
fnp-4682	309	34	larger	large	ADJ
fnp-4682	309	35	tissue	tissue	NOUN
fnp-4682	309	36	samples	sample	NOUN
fnp-4682	309	37	and	and	CCONJ
fnp-4682	309	38	performing	perform	VERB
fnp-4682	309	39	serial	serial	ADJ
fnp-4682	309	40	level	level	NOUN
fnp-4682	309	41	sections	section	NOUN
fnp-4682	309	42	will	will	AUX
fnp-4682	309	43	probably	probably	ADV
fnp-4682	309	44	help	help	VERB
fnp-4682	309	45	decrease	decrease	VERB
fnp-4682	309	46	the	the	DET
fnp-4682	309	47	number	number	NOUN
fnp-4682	309	48	of	of	ADP
fnp-4682	309	49	inadequate	inadequate	ADJ
fnp-4682	309	50	biopsies	biopsy	NOUN
fnp-4682	309	51	if	if	SCONJ
fnp-4682	309	52	this	this	DET
fnp-4682	309	53	evaluation	evaluation	NOUN
fnp-4682	309	54	becomes	become	VERB
fnp-4682	309	55	a	a	DET
fnp-4682	309	56	standard	standard	ADJ
fnp-4682	309	57	component	component	NOUN
fnp-4682	309	58	of	of	ADP
fnp-4682	309	59	the	the	DET
fnp-4682	309	60	als	als	NOUN
fnp-4682	309	61	diagnostic	diagnostic	ADJ
fnp-4682	309	62	work	work	NOUN
fnp-4682	309	63	-	-	PUNCT
fnp-4682	309	64	up	up	NOUN
fnp-4682	309	65	.	.	PUNCT
fnp-4682	310	1	advances	advance	NOUN
fnp-4682	310	2	in	in	ADP
fnp-4682	310	3	neuromuscular	neuromuscular	ADJ
fnp-4682	310	4	disease	disease	NOUN
fnp-4682	310	5	treatment	treatment	NOUN
fnp-4682	310	6	10	10	NUM
fnp-4682	310	7	.	.	PUNCT
fnp-4682	311	1	sarm1	sarm1	PROPN
fnp-4682	312	1	inhibitors	inhibitor	NOUN
fnp-4682	312	2	block	block	VERB
fnp-4682	312	3	wallerian	wallerian	NOUN
fnp-4682	312	4	degeneration	degeneration	NOUN
fnp-4682	312	5	in	in	ADP
fnp-4682	312	6	preclinical	preclinical	ADJ
fnp-4682	312	7	models	model	NOUN
fnp-4682	312	8	of	of	ADP
fnp-4682	312	9	axonal	axonal	ADJ
fnp-4682	312	10	neuropathy	neuropathy	ADJ
fnp-4682	312	11	as	as	SCONJ
fnp-4682	312	12	discussed	discuss	VERB
fnp-4682	312	13	in	in	ADP
fnp-4682	312	14	advance	advance	NOUN
fnp-4682	312	15	#	#	SYM
fnp-4682	312	16	4	4	NUM
fnp-4682	312	17	,	,	PUNCT
fnp-4682	312	18	sarm1	sarm1	PROPN
fnp-4682	312	19	is	be	AUX
fnp-4682	312	20	the	the	DET
fnp-4682	312	21	central	central	ADJ
fnp-4682	312	22	regulator	regulator	NOUN
fnp-4682	312	23	of	of	ADP
fnp-4682	312	24	intrinsic	intrinsic	ADJ
fnp-4682	312	25	axon	axon	NOUN
fnp-4682	312	26	destruction	destruction	NOUN
fnp-4682	312	27	program	program	NOUN
fnp-4682	312	28	/	/	SYM
fnp-4682	312	29	wallerian	wallerian	NOUN
fnp-4682	312	30	degeneration	degeneration	NOUN
fnp-4682	312	31	;	;	PUNCT
fnp-4682	312	32	deletion	deletion	NOUN
fnp-4682	312	33	of	of	ADP
fnp-4682	312	34	sarm1	sarm1	PROPN
fnp-4682	312	35	in	in	ADP
fnp-4682	312	36	mice	mice	NOUN
fnp-4682	312	37	prevents	prevent	VERB
fnp-4682	312	38	axonal	axonal	ADJ
fnp-4682	312	39	degeneration	degeneration	NOUN
fnp-4682	312	40	in	in	ADP
fnp-4682	312	41	both	both	DET
fnp-4682	312	42	cns	cns	NOUN
fnp-4682	312	43	(	(	PUNCT
fnp-4682	312	44	for	for	ADP
fnp-4682	312	45	example	example	NOUN
fnp-4682	312	46	,	,	PUNCT
fnp-4682	312	47	in	in	ADP
fnp-4682	312	48	mouse	mouse	NOUN
fnp-4682	312	49	models	model	NOUN
fnp-4682	312	50	of	of	ADP
fnp-4682	312	51	traumatic	traumatic	ADJ
fnp-4682	312	52	brain	brain	NOUN
fnp-4682	312	53	injury	injury	NOUN
fnp-4682	312	54	)	)	PUNCT
fnp-4682	312	55	and	and	CCONJ
fnp-4682	312	56	pns	pns	PROPN
fnp-4682	312	57	(	(	PUNCT
fnp-4682	312	58	in	in	ADP
fnp-4682	312	59	mouse	mouse	NOUN
fnp-4682	312	60	models	model	NOUN
fnp-4682	312	61	of	of	ADP
fnp-4682	312	62	axotomy	axotomy	ADJ
fnp-4682	312	63	and	and	CCONJ
fnp-4682	312	64	chemotherapy	chemotherapy	NOUN
fnp-4682	312	65	-	-	ADJ
fnp-4682	312	66	induced	induce	VERB
fnp-4682	312	67	peripheral	peripheral	ADJ
fnp-4682	312	68	neuropathy	neuropathy	ADJ
fnp-4682	312	69	)	)	PUNCT
fnp-4682	312	70	.	.	PUNCT
fnp-4682	313	1	the	the	DET
fnp-4682	313	2	central	central	ADJ
fnp-4682	313	3	role	role	NOUN
fnp-4682	313	4	of	of	ADP
fnp-4682	313	5	sarm1	sarm1	PROPN
fnp-4682	313	6	in	in	ADP
fnp-4682	313	7	wallerian	wallerian	ADJ
fnp-4682	313	8	degeneration	degeneration	NOUN
fnp-4682	313	9	raised	raise	VERB
fnp-4682	313	10	the	the	DET
fnp-4682	313	11	possibility	possibility	NOUN
fnp-4682	313	12	that	that	SCONJ
fnp-4682	313	13	sarm1	sarm1	PROPN
fnp-4682	313	14	blockade	blockade	NOUN
fnp-4682	313	15	would	would	AUX
fnp-4682	313	16	benefit	benefit	VERB
fnp-4682	313	17	patients	patient	NOUN
fnp-4682	313	18	with	with	ADP
fnp-4682	313	19	a	a	DET
fnp-4682	313	20	broad	broad	ADJ
fnp-4682	313	21	spectrum	spectrum	NOUN
fnp-4682	313	22	of	of	ADP
fnp-4682	313	23	neurologic	neurologic	ADJ
fnp-4682	313	24	disorders	disorder	NOUN
fnp-4682	313	25	,	,	PUNCT
fnp-4682	313	26	leading	lead	VERB
fnp-4682	313	27	to	to	ADP
fnp-4682	313	28	a	a	DET
fnp-4682	313	29	major	major	ADJ
fnp-4682	313	30	effort	effort	NOUN
fnp-4682	313	31	by	by	ADP
fnp-4682	313	32	multiple	multiple	ADJ
fnp-4682	313	33	different	different	ADJ
fnp-4682	313	34	research	research	NOUN
fnp-4682	313	35	groups	group	NOUN
fnp-4682	313	36	(	(	PUNCT
fnp-4682	313	37	both	both	CCONJ
fnp-4682	313	38	in	in	ADP
fnp-4682	313	39	academia	academia	NOUN
fnp-4682	313	40	and	and	CCONJ
fnp-4682	313	41	biotechnology	biotechnology	NOUN
fnp-4682	313	42	companies	company	NOUN
fnp-4682	313	43	)	)	PUNCT
fnp-4682	313	44	to	to	PART
fnp-4682	313	45	develop	develop	VERB
fnp-4682	313	46	small	small	ADJ
fnp-4682	313	47	molecule	molecule	NOUN
fnp-4682	313	48	inhibitors	inhibitor	NOUN
fnp-4682	313	49	of	of	ADP
fnp-4682	313	50	sarm1	sarm1	PROPN
fnp-4682	313	51	.	.	PUNCT
fnp-4682	314	1	initial	initial	ADJ
fnp-4682	314	2	proof	proof	NOUN
fnp-4682	314	3	-	-	PUNCT
fnp-4682	314	4	of	of	ADP
fnp-4682	314	5	-	-	PUNCT
fnp-4682	314	6	principle	principle	NOUN
fnp-4682	314	7	studies	study	NOUN
fnp-4682	314	8	with	with	ADP
fnp-4682	314	9	catalytic	catalytic	ADJ
fnp-4682	314	10	site	site	NOUN
fnp-4682	314	11	sarm1	sarm1	PUNCT
fnp-4682	315	1	inhibitors	inhibitor	NOUN
fnp-4682	315	2	were	be	AUX
fnp-4682	315	3	published	publish	VERB
fnp-4682	315	4	in	in	ADP
fnp-4682	315	5	2021	2021	NUM
fnp-4682	315	6	(	(	PUNCT
fnp-4682	315	7	bosanac	bosanac	NOUN
fnp-4682	315	8	et	et	PROPN
fnp-4682	315	9	al	al	PROPN
fnp-4682	315	10	.	.	PROPN
fnp-4682	315	11	,	,	PUNCT
fnp-4682	315	12	2021	2021	NUM
fnp-4682	315	13	;	;	PUNCT
fnp-4682	315	14	hughes	hughe	NOUN
fnp-4682	315	15	et	et	PROPN
fnp-4682	315	16	al	al	PROPN
fnp-4682	315	17	.	.	PROPN
fnp-4682	315	18	,	,	PUNCT
fnp-4682	315	19	2021	2021	NUM
fnp-4682	315	20	)	)	PUNCT
fnp-4682	315	21	,	,	PUNCT
fnp-4682	315	22	with	with	ADP
fnp-4682	315	23	more	more	ADV
fnp-4682	315	24	comprehensive	comprehensive	ADJ
fnp-4682	315	25	preclinical	preclinical	ADJ
fnp-4682	315	26	studies	study	NOUN
fnp-4682	315	27	of	of	ADP
fnp-4682	315	28	catalytic	catalytic	ADJ
fnp-4682	315	29	inhibitors	inhibitor	NOUN
fnp-4682	315	30	(	(	PUNCT
fnp-4682	315	31	bratkowski	bratkowski	NOUN
fnp-4682	315	32	et	et	PROPN
fnp-4682	315	33	al	al	PROPN
fnp-4682	315	34	.	.	PROPN
fnp-4682	315	35	,	,	PUNCT
fnp-4682	315	36	2022	2022	NUM
fnp-4682	315	37	;	;	PUNCT
fnp-4682	315	38	shi	shi	PROPN
fnp-4682	315	39	et	et	PROPN
fnp-4682	315	40	al	al	PROPN
fnp-4682	315	41	.	.	PROPN
fnp-4682	315	42	,	,	PUNCT
fnp-4682	315	43	2022	2022	NUM
fnp-4682	315	44	)	)	PUNCT
fnp-4682	315	45	and	and	CCONJ
fnp-4682	315	46	a	a	DET
fnp-4682	315	47	discovery	discovery	NOUN
fnp-4682	315	48	of	of	ADP
fnp-4682	315	49	a	a	DET
fnp-4682	315	50	new	new	ADJ
fnp-4682	315	51	class	class	NOUN
fnp-4682	315	52	of	of	ADP
fnp-4682	315	53	allosteric	allosteric	ADJ
fnp-4682	315	54	sarm1	sarm1	PUNCT
fnp-4682	316	1	inhibitors	inhibitor	NOUN
fnp-4682	316	2	(	(	PUNCT
fnp-4682	316	3	feldman	feldman	PROPN
fnp-4682	316	4	et	et	PROPN
fnp-4682	316	5	al	al	PROPN
fnp-4682	316	6	.	.	PROPN
fnp-4682	316	7	,	,	PUNCT
fnp-4682	316	8	2022	2022	NUM
fnp-4682	316	9	)	)	PUNCT
fnp-4682	316	10	reported	report	VERB
fnp-4682	316	11	in	in	ADP
fnp-4682	316	12	2022	2022	NUM
fnp-4682	316	13	.	.	PUNCT
fnp-4682	317	1	sarm1	sarm1	PROPN
fnp-4682	317	2	is	be	AUX
fnp-4682	317	3	a	a	DET
fnp-4682	317	4	multi	multi	ADJ
fnp-4682	317	5	-	-	ADJ
fnp-4682	317	6	domain	domain	ADJ
fnp-4682	317	7	enzyme	enzyme	NOUN
fnp-4682	317	8	that	that	DET
fnp-4682	317	9	functions	function	NOUN
fnp-4682	317	10	as	as	ADP
fnp-4682	317	11	an	an	DET
fnp-4682	317	12	oligomer	oligomer	NOUN
fnp-4682	317	13	;	;	PUNCT
fnp-4682	317	14	it	it	PRON
fnp-4682	317	15	contains	contain	VERB
fnp-4682	317	16	an	an	DET
fnp-4682	317	17	auto	auto	NOUN
fnp-4682	317	18	-	-	PUNCT
fnp-4682	317	19	inhibitory	inhibitory	NOUN
fnp-4682	317	20	n	n	CCONJ
fnp-4682	317	21	-	-	PUNCT
fnp-4682	317	22	terminal	terminal	ADJ
fnp-4682	317	23	armadillo	armadillo	NOUN
fnp-4682	317	24	repeat	repeat	NOUN
fnp-4682	317	25	(	(	PUNCT
fnp-4682	317	26	arm	arm	NOUN
fnp-4682	317	27	)	)	PUNCT
fnp-4682	317	28	domain	domain	NOUN
fnp-4682	317	29	,	,	PUNCT
fnp-4682	317	30	repeat	repeat	VERB
fnp-4682	317	31	sterile	sterile	ADJ
fnp-4682	317	32	alpha	alpha	NOUN
fnp-4682	317	33	motif	motif	NOUN
fnp-4682	317	34	(	(	PUNCT
fnp-4682	317	35	sam	sam	PROPN
fnp-4682	317	36	)	)	PUNCT
fnp-4682	317	37	domains	domain	NOUN
fnp-4682	317	38	that	that	PRON
fnp-4682	317	39	are	be	AUX
fnp-4682	317	40	required	require	VERB
fnp-4682	317	41	for	for	ADP
fnp-4682	317	42	dimerization	dimerization	NOUN
fnp-4682	317	43	/	/	SYM
fnp-4682	317	44	oligomerization	oligomerization	NOUN
fnp-4682	317	45	,	,	PUNCT
fnp-4682	317	46	and	and	CCONJ
fnp-4682	317	47	a	a	DET
fnp-4682	317	48	catalytic	catalytic	ADJ
fnp-4682	317	49	c	c	X
fnp-4682	317	50	-	-	PUNCT
fnp-4682	317	51	terminal	terminal	ADJ
fnp-4682	317	52	domain	domain	NOUN
fnp-4682	317	53	that	that	PRON
fnp-4682	317	54	includes	include	VERB
fnp-4682	317	55	the	the	DET
fnp-4682	317	56	toll	toll	NOUN
fnp-4682	317	57	/	/	SYM
fnp-4682	317	58	interleukin	interleukin	NOUN
fnp-4682	317	59	receptor	receptor	NOUN
fnp-4682	317	60	(	(	PUNCT
fnp-4682	317	61	tir	tir	NOUN
fnp-4682	317	62	)	)	PUNCT
fnp-4682	317	63	motif	motif	NOUN
fnp-4682	317	64	.	.	PUNCT
fnp-4682	318	1	the	the	DET
fnp-4682	318	2	tir	tir	PROPN
fnp-4682	318	3	domain	domain	NOUN
fnp-4682	318	4	contains	contain	VERB
fnp-4682	318	5	the	the	DET
fnp-4682	318	6	nad+	nad+	PROPN
fnp-4682	318	7	hydrolase	hydrolase	NOUN
fnp-4682	318	8	activity	activity	NOUN
fnp-4682	318	9	that	that	PRON
fnp-4682	318	10	catabolizes	catabolize	VERB
fnp-4682	318	11	nad+	nad+	PROPN
fnp-4682	318	12	into	into	ADP
fnp-4682	318	13	nicotinamide	nicotinamide	NOUN
fnp-4682	318	14	,	,	PUNCT
fnp-4682	318	15	adenosine	adenosine	ADJ
fnp-4682	318	16	diphosphate	diphosphate	NOUN
fnp-4682	318	17	ribose	ribose	NOUN
fnp-4682	318	18	(	(	PUNCT
fnp-4682	318	19	adpr	adpr	ADJ
fnp-4682	318	20	)	)	PUNCT
fnp-4682	318	21	,	,	PUNCT
fnp-4682	318	22	and	and	CCONJ
fnp-4682	318	23	cyclic	cyclic	ADJ
fnp-4682	318	24	adpr	adpr	NOUN
fnp-4682	318	25	(	(	PUNCT
fnp-4682	318	26	which	which	PRON
fnp-4682	318	27	is	be	AUX
fnp-4682	318	28	the	the	DET
fnp-4682	318	29	second	second	ADJ
fnp-4682	318	30	messenger	messenger	NOUN
fnp-4682	318	31	that	that	PRON
fnp-4682	318	32	triggers	trigger	VERB
fnp-4682	318	33	the	the	DET
fnp-4682	318	34	wallerian	wallerian	ADJ
fnp-4682	318	35	degeneration	degeneration	NOUN
fnp-4682	318	36	pathway	pathway	NOUN
fnp-4682	318	37	)	)	PUNCT
fnp-4682	318	38	.	.	PUNCT
fnp-4682	319	1	under	under	ADP
fnp-4682	319	2	normal	normal	ADJ
fnp-4682	319	3	conditions	condition	NOUN
fnp-4682	319	4	,	,	PUNCT
fnp-4682	319	5	nad+	nad+	PROPN
fnp-4682	319	6	is	be	AUX
fnp-4682	319	7	bound	bind	VERB
fnp-4682	319	8	to	to	ADP
fnp-4682	319	9	the	the	DET
fnp-4682	319	10	arm	arm	NOUN
fnp-4682	319	11	domain	domain	NOUN
fnp-4682	319	12	,	,	PUNCT
fnp-4682	319	13	resulting	result	VERB
fnp-4682	319	14	in	in	ADP
fnp-4682	319	15	autoinhibition	autoinhibition	NOUN
fnp-4682	319	16	of	of	ADP
fnp-4682	319	17	the	the	DET
fnp-4682	319	18	sarm1	sarm1	PROPN
fnp-4682	319	19	activity	activity	NOUN
fnp-4682	319	20	;	;	PUNCT
fnp-4682	319	21	when	when	SCONJ
fnp-4682	319	22	the	the	DET
fnp-4682	319	23	nmn	nmn	PROPN
fnp-4682	319	24	/	/	SYM
fnp-4682	319	25	nad+	nad+	PROPN
fnp-4682	319	26	ratio	ratio	NOUN
fnp-4682	319	27	increases	increase	NOUN
fnp-4682	319	28	(	(	PUNCT
fnp-4682	319	29	typically	typically	ADV
fnp-4682	319	30	due	due	ADJ
fnp-4682	319	31	to	to	ADP
fnp-4682	319	32	a	a	DET
fnp-4682	319	33	decreased	decrease	VERB
fnp-4682	319	34	production	production	NOUN
fnp-4682	319	35	of	of	ADP
fnp-4682	319	36	nad+	nad+	PROPN
fnp-4682	319	37	by	by	ADP
fnp-4682	319	38	nmnat2	nmnat2	NOUN
fnp-4682	319	39	)	)	PUNCT
fnp-4682	319	40	,	,	PUNCT
fnp-4682	319	41	nmn	nmn	PROPN
fnp-4682	319	42	binds	bind	VERB
fnp-4682	319	43	to	to	ADP
fnp-4682	319	44	the	the	DET
fnp-4682	319	45	arm	arm	NOUN
fnp-4682	319	46	domain	domain	NOUN
fnp-4682	319	47	instead	instead	ADV
fnp-4682	319	48	of	of	ADP
fnp-4682	319	49	nad+	nad+	NOUN
fnp-4682	319	50	,	,	PUNCT
fnp-4682	319	51	resulting	result	VERB
fnp-4682	319	52	in	in	ADP
fnp-4682	319	53	a	a	DET
fnp-4682	319	54	conformational	conformational	ADJ
fnp-4682	319	55	change	change	NOUN
fnp-4682	319	56	that	that	PRON
fnp-4682	319	57	leads	lead	VERB
fnp-4682	319	58	to	to	ADP
fnp-4682	319	59	oligomerization	oligomerization	NOUN
fnp-4682	319	60	of	of	ADP
fnp-4682	319	61	the	the	DET
fnp-4682	319	62	tir	tir	PROPN
fnp-4682	319	63	domain	domain	NOUN
fnp-4682	319	64	and	and	CCONJ
fnp-4682	319	65	relief	relief	NOUN
fnp-4682	319	66	of	of	ADP
fnp-4682	319	67	sarm	sarm	PROPN
fnp-4682	319	68	1	1	NUM
fnp-4682	319	69	autoinhibition	autoinhibition	NOUN
fnp-4682	319	70	(	(	PUNCT
fnp-4682	319	71	feldman	feldman	PROPN
fnp-4682	319	72	et	et	PROPN
fnp-4682	319	73	al	al	PROPN
fnp-4682	319	74	.	.	PROPN
fnp-4682	319	75	,	,	PUNCT
fnp-4682	319	76	2022	2022	NUM
fnp-4682	319	77	)	)	PUNCT
fnp-4682	319	78	.	.	PUNCT
fnp-4682	320	1	several	several	ADJ
fnp-4682	320	2	groups	group	NOUN
fnp-4682	320	3	have	have	AUX
fnp-4682	320	4	developed	develop	VERB
fnp-4682	320	5	non	non	ADJ
fnp-4682	320	6	-	-	ADJ
fnp-4682	320	7	competitive	competitive	ADJ
fnp-4682	320	8	,	,	PUNCT
fnp-4682	320	9	adduct	adduct	NOUN
fnp-4682	320	10	-	-	PUNCT
fnp-4682	320	11	forming	form	VERB
fnp-4682	320	12	small	small	ADJ
fnp-4682	320	13	molecule	molecule	NOUN
fnp-4682	320	14	inhibitors	inhibitor	NOUN
fnp-4682	320	15	of	of	ADP
fnp-4682	320	16	the	the	DET
fnp-4682	320	17	sarm1	sarm1	PROPN
fnp-4682	320	18	nad+	nad+	PROPN
fnp-4682	320	19	hydrolase	hydrolase	NOUN
fnp-4682	320	20	site	site	NOUN
fnp-4682	320	21	,	,	PUNCT
fnp-4682	320	22	with	with	ADP
fnp-4682	320	23	most	most	ADJ
fnp-4682	320	24	comprehensive	comprehensive	ADJ
fnp-4682	320	25	characterization	characterization	NOUN
fnp-4682	320	26	to	to	ADP
fnp-4682	320	27	date	date	NOUN
fnp-4682	320	28	reported	report	VERB
fnp-4682	320	29	by	by	ADP
fnp-4682	320	30	bratkowski	bratkowski	NOUN
fnp-4682	320	31	and	and	CCONJ
fnp-4682	320	32	colleagues	colleague	NOUN
fnp-4682	320	33	.	.	PUNCT
fnp-4682	321	1	these	these	DET
fnp-4682	321	2	non	non	ADJ
fnp-4682	321	3	-	-	ADJ
fnp-4682	321	4	competitive	competitive	ADJ
fnp-4682	321	5	sarm1	sarm1	NOUN
fnp-4682	321	6	inhibitors	inhibitor	NOUN
fnp-4682	321	7	function	function	VERB
fnp-4682	321	8	as	as	ADP
fnp-4682	321	9	pseudo	pseudo	NOUN
fnp-4682	321	10	-	-	NOUN
fnp-4682	321	11	substrates	substrate	NOUN
fnp-4682	321	12	/	/	SYM
fnp-4682	321	13	pro	pro	ADJ
fnp-4682	321	14	-	-	NOUN
fnp-4682	321	15	drugs	drug	NOUN
fnp-4682	321	16	that	that	PRON
fnp-4682	321	17	intercept	intercept	VERB
fnp-4682	321	18	nad+	nad+	PROPN
fnp-4682	321	19	hydrolysis	hydrolysis	NOUN
fnp-4682	321	20	and	and	CCONJ
fnp-4682	321	21	form	form	VERB
fnp-4682	321	22	inhibitor	inhibitor	NOUN
fnp-4682	321	23	-	-	PUNCT
fnp-4682	321	24	adpr	adpr	NOUN
fnp-4682	321	25	adducts	adduct	NOUN
fnp-4682	321	26	,	,	PUNCT
fnp-4682	321	27	which	which	PRON
fnp-4682	321	28	act	act	VERB
fnp-4682	321	29	as	as	ADV
fnp-4682	321	30	highly	highly	ADV
fnp-4682	321	31	potent	potent	ADJ
fnp-4682	321	32	inhibitors	inhibitor	NOUN
fnp-4682	321	33	of	of	ADP
fnp-4682	321	34	the	the	DET
fnp-4682	321	35	catalytic	catalytic	ADJ
fnp-4682	321	36	site	site	NOUN
fnp-4682	321	37	,	,	PUNCT
fnp-4682	321	38	with	with	ADP
fnp-4682	321	39	slow	slow	ADJ
fnp-4682	321	40	on	on	ADP
fnp-4682	321	41	and	and	CCONJ
fnp-4682	321	42	off	off	ADP
fnp-4682	321	43	rates	rate	NOUN
fnp-4682	321	44	and	and	CCONJ
fnp-4682	321	45	the	the	DET
fnp-4682	321	46	dissociation	dissociation	NOUN
fnp-4682	321	47	constant	constant	ADJ
fnp-4682	321	48	in	in	ADP
fnp-4682	321	49	the	the	DET
fnp-4682	321	50	low	low	ADJ
fnp-4682	321	51	nanomolar	nanomolar	ADJ
fnp-4682	321	52	range	range	NOUN
fnp-4682	321	53	.	.	PUNCT
fnp-4682	322	1	while	while	SCONJ
fnp-4682	322	2	all	all	DET
fnp-4682	322	3	studies	study	NOUN
fnp-4682	322	4	have	have	AUX
fnp-4682	322	5	shown	show	VERB
fnp-4682	322	6	that	that	SCONJ
fnp-4682	322	7	these	these	DET
fnp-4682	322	8	catalytic	catalytic	ADJ
fnp-4682	322	9	site	site	NOUN
fnp-4682	322	10	inhibitors	inhibitor	NOUN
fnp-4682	322	11	prevent	prevent	VERB
fnp-4682	322	12	axonal	axonal	ADJ
fnp-4682	322	13	degeneration	degeneration	NOUN
fnp-4682	322	14	in	in	ADP
fnp-4682	322	15	vitro	vitro	X
fnp-4682	322	16	,	,	PUNCT
fnp-4682	322	17	bratkowski	bratkowski	NOUN
fnp-4682	322	18	et	et	PROPN
fnp-4682	322	19	al	al	PROPN
fnp-4682	322	20	.	.	PROPN
fnp-4682	322	21	went	go	VERB
fnp-4682	322	22	beyond	beyond	ADP
fnp-4682	322	23	cellular	cellular	ADJ
fnp-4682	322	24	axon	axon	NOUN
fnp-4682	322	25	injury	injury	NOUN
fnp-4682	322	26	models	model	NOUN
fnp-4682	322	27	:	:	PUNCT
fnp-4682	322	28	they	they	PRON
fnp-4682	322	29	used	use	VERB
fnp-4682	322	30	preclinical	preclinical	ADJ
fnp-4682	322	31	mouse	mouse	NOUN
fnp-4682	322	32	models	model	NOUN
fnp-4682	322	33	of	of	ADP
fnp-4682	322	34	acute	acute	ADJ
fnp-4682	322	35	peripheral	peripheral	ADJ
fnp-4682	322	36	nerve	nerve	NOUN
fnp-4682	322	37	injury	injury	NOUN
fnp-4682	322	38	(	(	PUNCT
fnp-4682	322	39	a	a	DET
fnp-4682	322	40	sciatic	sciatic	ADJ
fnp-4682	322	41	nerve	nerve	NOUN
fnp-4682	322	42	transection	transection	NOUN
fnp-4682	322	43	model	model	NOUN
fnp-4682	322	44	and	and	CCONJ
fnp-4682	322	45	a	a	DET
fnp-4682	322	46	model	model	NOUN
fnp-4682	322	47	of	of	ADP
fnp-4682	322	48	vincristine	vincristine	NOUN
fnp-4682	322	49	-	-	PUNCT
fnp-4682	322	50	induced	induce	VERB
fnp-4682	322	51	peripheral	peripheral	ADJ
fnp-4682	322	52	neuropathy	neuropathy	ADJ
fnp-4682	322	53	)	)	PUNCT
fnp-4682	322	54	to	to	PART
fnp-4682	322	55	demonstrate	demonstrate	VERB
fnp-4682	322	56	that	that	SCONJ
fnp-4682	322	57	these	these	DET
fnp-4682	322	58	drugs	drug	NOUN
fnp-4682	322	59	are	be	AUX
fnp-4682	322	60	both	both	ADV
fnp-4682	322	61	safe	safe	ADJ
fnp-4682	322	62	and	and	CCONJ
fnp-4682	322	63	effective	effective	ADJ
fnp-4682	322	64	in	in	ADP
fnp-4682	322	65	vivo	vivo	NOUN
fnp-4682	322	66	,	,	PUNCT
fnp-4682	322	67	with	with	ADP
fnp-4682	322	68	efficacy	efficacy	NOUN
fnp-4682	322	69	approaching	approach	VERB
fnp-4682	322	70	the	the	DET
fnp-4682	322	71	efficacy	efficacy	NOUN
fnp-4682	322	72	of	of	ADP
fnp-4682	322	73	genetic	genetic	ADJ
fnp-4682	322	74	sarm1	sarm1	PROPN
fnp-4682	322	75	deletion	deletion	NOUN
fnp-4682	322	76	.	.	PUNCT
fnp-4682	323	1	specifically	specifically	ADV
fnp-4682	323	2	,	,	PUNCT
fnp-4682	323	3	treatment	treatment	NOUN
fnp-4682	323	4	with	with	ADP
fnp-4682	323	5	nb-3	nb-3	PRON
fnp-4682	323	6	(	(	PUNCT
fnp-4682	323	7	the	the	DET
fnp-4682	323	8	compound	compound	NOUN
fnp-4682	323	9	with	with	ADP
fnp-4682	323	10	chemical	chemical	NOUN
fnp-4682	323	11	properties	property	NOUN
fnp-4682	323	12	most	most	ADV
fnp-4682	323	13	suitable	suitable	ADJ
fnp-4682	323	14	for	for	ADP
fnp-4682	323	15	in	in	ADP
fnp-4682	323	16	vivo	vivo	ADJ
fnp-4682	323	17	use	use	NOUN
fnp-4682	323	18	)	)	PUNCT
fnp-4682	323	19	suppressed	suppress	VERB
fnp-4682	323	20	an	an	DET
fnp-4682	323	21	increase	increase	NOUN
fnp-4682	323	22	in	in	ADP
fnp-4682	323	23	the	the	DET
fnp-4682	323	24	plasma	plasma	NOUN
fnp-4682	323	25	level	level	NOUN
fnp-4682	323	26	of	of	ADP
fnp-4682	323	27	neurofilament	neurofilament	ADJ
fnp-4682	323	28	light	light	NOUN
fnp-4682	323	29	chain	chain	NOUN
fnp-4682	323	30	(	(	PUNCT
fnp-4682	323	31	a	a	DET
fnp-4682	323	32	biomarker	biomarker	NOUN
fnp-4682	323	33	of	of	ADP
fnp-4682	323	34	axonal	axonal	ADJ
fnp-4682	323	35	injury	injury	NOUN
fnp-4682	323	36	)	)	PUNCT
fnp-4682	323	37	and	and	CCONJ
fnp-4682	323	38	led	lead	VERB
fnp-4682	323	39	to	to	ADP
fnp-4682	323	40	preservation	preservation	NOUN
fnp-4682	323	41	of	of	ADP
fnp-4682	323	42	distal	distal	ADJ
fnp-4682	323	43	nerve	nerve	NOUN
fnp-4682	323	44	fiber	fiber	NOUN
fnp-4682	323	45	integrity	integrity	NOUN
fnp-4682	323	46	in	in	ADP
fnp-4682	323	47	both	both	DET
fnp-4682	323	48	acute	acute	ADJ
fnp-4682	323	49	nerve	nerve	NOUN
fnp-4682	323	50	injury	injury	NOUN
fnp-4682	323	51	models	model	NOUN
fnp-4682	323	52	;	;	PUNCT
fnp-4682	323	53	in	in	ADP
fnp-4682	323	54	addition	addition	NOUN
fnp-4682	323	55	,	,	PUNCT
fnp-4682	323	56	it	it	PRON
fnp-4682	323	57	attenuated	attenuate	VERB
fnp-4682	323	58	toxin	toxin	NOUN
fnp-4682	323	59	-	-	PUNCT
fnp-4682	323	60	induced	induce	VERB
fnp-4682	323	61	allodynia	allodynia	ADJ
fnp-4682	323	62	/	/	SYM
fnp-4682	323	63	neuropathic	neuropathic	ADJ
fnp-4682	323	64	pain	pain	NOUN
fnp-4682	323	65	in	in	ADP
fnp-4682	323	66	the	the	DET
fnp-4682	323	67	vincristine	vincristine	NOUN
fnp-4682	323	68	model	model	NOUN
fnp-4682	323	69	.	.	PUNCT
fnp-4682	324	1	(	(	PUNCT
fnp-4682	324	2	the	the	DET
fnp-4682	324	3	transection	transection	NOUN
fnp-4682	324	4	model	model	NOUN
fnp-4682	324	5	can	can	AUX
fnp-4682	324	6	not	not	PART
fnp-4682	324	7	be	be	AUX
fnp-4682	324	8	used	use	VERB
fnp-4682	324	9	for	for	ADP
fnp-4682	324	10	functional	functional	ADJ
fnp-4682	324	11	studies	study	NOUN
fnp-4682	324	12	because	because	SCONJ
fnp-4682	324	13	connections	connection	NOUN
fnp-4682	324	14	between	between	ADP
fnp-4682	324	15	the	the	DET
fnp-4682	324	16	cns	cns	NOUN
fnp-4682	324	17	and	and	CCONJ
fnp-4682	324	18	periphery	periphery	NOUN
fnp-4682	324	19	are	be	AUX
fnp-4682	324	20	completely	completely	ADV
fnp-4682	324	21	disrupted	disrupt	VERB
fnp-4682	324	22	.	.	PUNCT
fnp-4682	324	23	)	)	PUNCT
fnp-4682	325	1	critically	critically	ADV
fnp-4682	325	2	,	,	PUNCT
fnp-4682	325	3	the	the	DET
fnp-4682	325	4	nb-3	nb-3	PRON
fnp-4682	325	5	treatment	treatment	NOUN
fnp-4682	325	6	was	be	AUX
fnp-4682	325	7	effective	effective	ADJ
fnp-4682	325	8	not	not	PART
fnp-4682	325	9	only	only	ADV
fnp-4682	325	10	when	when	SCONJ
fnp-4682	325	11	it	it	PRON
fnp-4682	325	12	was	be	AUX
fnp-4682	325	13	administered	administer	VERB
fnp-4682	325	14	prophylactically	prophylactically	ADV
fnp-4682	325	15	but	but	CCONJ
fnp-4682	325	16	also	also	ADV
fnp-4682	325	17	when	when	SCONJ
fnp-4682	325	18	it	it	PRON
fnp-4682	325	19	was	be	AUX
fnp-4682	325	20	given	give	VERB
fnp-4682	325	21	several	several	ADJ
fnp-4682	325	22	hours	hour	NOUN
fnp-4682	325	23	after	after	ADP
fnp-4682	325	24	injury	injury	NOUN
fnp-4682	325	25	,	,	PUNCT
fnp-4682	325	26	a	a	DET
fnp-4682	325	27	treatment	treatment	NOUN
fnp-4682	325	28	paradigm	paradigm	NOUN
fnp-4682	325	29	that	that	PRON
fnp-4682	325	30	is	be	AUX
fnp-4682	325	31	more	more	ADV
fnp-4682	325	32	relevant	relevant	ADJ
fnp-4682	325	33	for	for	ADP
fnp-4682	325	34	potential	potential	ADJ
fnp-4682	325	35	clinical	clinical	ADJ
fnp-4682	325	36	use	use	NOUN
fnp-4682	325	37	.	.	PUNCT
fnp-4682	326	1	in	in	ADP
fnp-4682	326	2	a	a	DET
fnp-4682	326	3	separate	separate	ADJ
fnp-4682	326	4	line	line	NOUN
fnp-4682	326	5	of	of	ADP
fnp-4682	326	6	the	the	DET
fnp-4682	326	7	sarm1	sarm1	PROPN
fnp-4682	326	8	inhibitor	inhibitor	PROPN
fnp-4682	326	9	research	research	PROPN
fnp-4682	326	10	,	,	PUNCT
fnp-4682	326	11	feldman	feldman	PROPN
fnp-4682	326	12	and	and	CCONJ
fnp-4682	326	13	colleagues	colleague	NOUN
fnp-4682	326	14	used	use	VERB
fnp-4682	326	15	a	a	DET
fnp-4682	326	16	chemical	chemical	ADJ
fnp-4682	326	17	proteomic	proteomic	ADJ
fnp-4682	326	18	approach	approach	NOUN
fnp-4682	326	19	to	to	PART
fnp-4682	326	20	discover	discover	VERB
fnp-4682	326	21	an	an	DET
fnp-4682	326	22	entirely	entirely	ADV
fnp-4682	326	23	novel	novel	ADJ
fnp-4682	326	24	class	class	NOUN
fnp-4682	326	25	of	of	ADP
fnp-4682	326	26	sarm1	sarm1	PROPN
fnp-4682	326	27	inhibitors	inhibitor	NOUN
fnp-4682	326	28	:	:	PUNCT
fnp-4682	326	29	these	these	DET
fnp-4682	326	30	electrophilic	electrophilic	ADJ
fnp-4682	326	31	compounds	compound	NOUN
fnp-4682	326	32	(	(	PUNCT
fnp-4682	326	33	tryptoline	tryptoline	NOUN
fnp-4682	326	34	acrylamides	acrylamide	VERB
fnp-4682	326	35	)	)	PUNCT
fnp-4682	326	36	target	target	NOUN
fnp-4682	326	37	cysteine	cysteine	NOUN
fnp-4682	326	38	c311	c311	PROPN
fnp-4682	326	39	in	in	ADP
fnp-4682	326	40	the	the	DET
fnp-4682	326	41	autoregulatory	autoregulatory	ADJ
fnp-4682	326	42	arm	arm	NOUN
fnp-4682	326	43	domain	domain	NOUN
fnp-4682	326	44	,	,	PUNCT
fnp-4682	326	45	resulting	result	VERB
fnp-4682	326	46	in	in	ADP
fnp-4682	326	47	allosteric	allosteric	ADJ
fnp-4682	326	48	inhibition	inhibition	NOUN
fnp-4682	326	49	of	of	ADP
fnp-4682	326	50	sarm1	sarm1	X
fnp-4682	326	51	enzymatic	enzymatic	ADJ
fnp-4682	326	52	activity	activity	NOUN
fnp-4682	326	53	(	(	PUNCT
fnp-4682	326	54	feldman	feldman	PROPN
fnp-4682	326	55	et	et	PROPN
fnp-4682	326	56	al	al	PROPN
fnp-4682	326	57	.	.	PROPN
fnp-4682	326	58	,	,	PUNCT
fnp-4682	326	59	2022	2022	NUM
fnp-4682	326	60	)	)	PUNCT
fnp-4682	326	61	.	.	PUNCT
fnp-4682	327	1	thus	thus	ADV
fnp-4682	327	2	far	far	ADV
fnp-4682	327	3	,	,	PUNCT
fnp-4682	327	4	these	these	DET
fnp-4682	327	5	new	new	ADJ
fnp-4682	327	6	compounds	compound	NOUN
fnp-4682	327	7	were	be	AUX
fnp-4682	327	8	evaluated	evaluate	VERB
fnp-4682	327	9	only	only	ADV
fnp-4682	327	10	in	in	ADP
fnp-4682	327	11	the	the	DET
fnp-4682	327	12	cellular	cellular	ADJ
fnp-4682	327	13	models	model	NOUN
fnp-4682	327	14	of	of	ADP
fnp-4682	327	15	axon	axon	NOUN
fnp-4682	327	16	degeneration	degeneration	NOUN
fnp-4682	327	17	,	,	PUNCT
fnp-4682	327	18	where	where	SCONJ
fnp-4682	327	19	their	their	PRON
fnp-4682	327	20	efficacy	efficacy	NOUN
fnp-4682	327	21	was	be	AUX
fnp-4682	327	22	similar	similar	ADJ
fnp-4682	327	23	to	to	ADP
fnp-4682	327	24	the	the	DET
fnp-4682	327	25	efficacy	efficacy	NOUN
fnp-4682	327	26	of	of	ADP
fnp-4682	327	27	catalytic	catalytic	ADJ
fnp-4682	327	28	site	site	NOUN
fnp-4682	327	29	inhibitors	inhibitor	NOUN
fnp-4682	327	30	;	;	PUNCT
fnp-4682	327	31	it	it	PRON
fnp-4682	327	32	remains	remain	VERB
fnp-4682	327	33	to	to	PART
fnp-4682	327	34	be	be	AUX
fnp-4682	327	35	determined	determine	VERB
fnp-4682	327	36	whether	whether	SCONJ
fnp-4682	327	37	they	they	PRON
fnp-4682	327	38	will	will	AUX
fnp-4682	327	39	be	be	AUX
fnp-4682	327	40	similarly	similarly	ADV
fnp-4682	327	41	safe	safe	ADJ
fnp-4682	327	42	and	and	CCONJ
fnp-4682	327	43	effective	effective	ADJ
fnp-4682	327	44	in	in	ADP
fnp-4682	327	45	vivo	vivo	NOUN
fnp-4682	327	46	.	.	PUNCT
fnp-4682	328	1	regardless	regardless	ADV
fnp-4682	328	2	of	of	ADP
fnp-4682	328	3	the	the	DET
fnp-4682	328	4	in	in	ADP
fnp-4682	328	5	vivo	vivo	ADJ
fnp-4682	328	6	effectiveness	effectiveness	NOUN
fnp-4682	328	7	of	of	ADP
fnp-4682	328	8	these	these	DET
fnp-4682	328	9	specific	specific	ADJ
fnp-4682	328	10	compounds	compound	NOUN
fnp-4682	328	11	,	,	PUNCT
fnp-4682	328	12	this	this	DET
fnp-4682	328	13	study	study	NOUN
fnp-4682	328	14	provides	provide	VERB
fnp-4682	328	15	initial	initial	ADJ
fnp-4682	328	16	evidence	evidence	NOUN
fnp-4682	328	17	that	that	SCONJ
fnp-4682	328	18	sarm1	sarm1	PROPN
fnp-4682	328	19	can	can	AUX
fnp-4682	328	20	be	be	AUX
fnp-4682	328	21	pharmacologically	pharmacologically	ADV
fnp-4682	328	22	inhibited	inhibit	VERB
fnp-4682	328	23	through	through	ADP
fnp-4682	328	24	allosteric	allosteric	NOUN
fnp-4682	328	25	as	as	ADV
fnp-4682	328	26	well	well	ADV
fnp-4682	328	27	as	as	ADP
fnp-4682	328	28	enzymatic	enzymatic	ADJ
fnp-4682	328	29	mechanisms	mechanism	NOUN
fnp-4682	328	30	;	;	PUNCT
fnp-4682	328	31	because	because	SCONJ
fnp-4682	328	32	different	different	ADJ
fnp-4682	328	33	classes	class	NOUN
fnp-4682	328	34	of	of	ADP
fnp-4682	328	35	sarm1	sarm1	PROPN
fnp-4682	328	36	inhibitors	inhibitor	NOUN
fnp-4682	328	37	are	be	AUX
fnp-4682	328	38	likely	likely	ADJ
fnp-4682	328	39	to	to	PART
fnp-4682	328	40	have	have	VERB
fnp-4682	328	41	different	different	ADJ
fnp-4682	328	42	side	side	NOUN
fnp-4682	328	43	effects	effect	NOUN
fnp-4682	328	44	and	and	CCONJ
fnp-4682	328	45	different	different	ADJ
fnp-4682	328	46	optimal	optimal	ADJ
fnp-4682	328	47	clinical	clinical	ADJ
fnp-4682	328	48	uses	use	NOUN
fnp-4682	328	49	,	,	PUNCT
fnp-4682	328	50	this	this	DET
fnp-4682	328	51	finding	finding	NOUN
fnp-4682	328	52	is	be	AUX
fnp-4682	328	53	both	both	ADV
fnp-4682	328	54	important	important	ADJ
fnp-4682	328	55	and	and	CCONJ
fnp-4682	328	56	exciting	exciting	ADJ
fnp-4682	328	57	.	.	PUNCT
fnp-4682	329	1	where	where	SCONJ
fnp-4682	329	2	is	be	AUX
fnp-4682	329	3	this	this	DET
fnp-4682	329	4	research	research	NOUN
fnp-4682	329	5	headed	head	VERB
fnp-4682	329	6	?	?	PUNCT
fnp-4682	330	1	first	first	ADV
fnp-4682	330	2	,	,	PUNCT
fnp-4682	330	3	there	there	PRON
fnp-4682	330	4	should	should	AUX
fnp-4682	330	5	be	be	AUX
fnp-4682	330	6	additional	additional	ADJ
fnp-4682	330	7	preclinical	preclinical	ADJ
fnp-4682	330	8	testing	testing	NOUN
fnp-4682	330	9	of	of	ADP
fnp-4682	330	10	all	all	DET
fnp-4682	330	11	compounds	compound	NOUN
fnp-4682	330	12	discovered	discover	VERB
fnp-4682	330	13	to	to	ADP
fnp-4682	330	14	date	date	NOUN
fnp-4682	330	15	using	use	VERB
fnp-4682	330	16	models	model	NOUN
fnp-4682	330	17	of	of	ADP
fnp-4682	330	18	chronic	chronic	ADJ
fnp-4682	330	19	axonal	axonal	ADJ
fnp-4682	330	20	injury	injury	NOUN
fnp-4682	330	21	(	(	PUNCT
fnp-4682	330	22	including	include	VERB
fnp-4682	330	23	the	the	DET
fnp-4682	330	24	nmnat2	nmnat2	NOUN
fnp-4682	330	25	deficiency	deficiency	NOUN
fnp-4682	330	26	model	model	NOUN
fnp-4682	330	27	described	describe	VERB
fnp-4682	330	28	in	in	ADP
fnp-4682	330	29	advance	advance	NOUN
fnp-4682	330	30	#	#	SYM
fnp-4682	330	31	4	4	NUM
fnp-4682	330	32	)	)	PUNCT
fnp-4682	330	33	that	that	PRON
fnp-4682	330	34	more	more	ADV
fnp-4682	330	35	closely	closely	ADV
fnp-4682	330	36	resemble	resemble	VERB
fnp-4682	330	37	clinical	clinical	ADJ
fnp-4682	330	38	scenarios	scenario	NOUN
fnp-4682	330	39	where	where	SCONJ
fnp-4682	330	40	sarm1	sarm1	PROPN
fnp-4682	330	41	inhibitors	inhibitor	NOUN
fnp-4682	330	42	will	will	AUX
fnp-4682	330	43	be	be	AUX
fnp-4682	330	44	used	use	VERB
fnp-4682	330	45	.	.	PUNCT
fnp-4682	331	1	[	[	X
fnp-4682	331	2	in	in	ADP
fnp-4682	331	3	the	the	DET
fnp-4682	331	4	setting	setting	NOUN
fnp-4682	331	5	of	of	ADP
fnp-4682	331	6	catastrophic	catastrophic	ADJ
fnp-4682	331	7	acute	acute	ADJ
fnp-4682	331	8	axonal	axonal	ADJ
fnp-4682	331	9	injury	injury	NOUN
fnp-4682	331	10	,	,	PUNCT
fnp-4682	331	11	degeneration	degeneration	NOUN
fnp-4682	331	12	of	of	ADP
fnp-4682	331	13	the	the	DET
fnp-4682	331	14	distal	distal	ADJ
fnp-4682	331	15	segment	segment	NOUN
fnp-4682	331	16	of	of	ADP
fnp-4682	331	17	the	the	DET
fnp-4682	331	18	injured	injure	VERB
fnp-4682	331	19	axon	axon	NOUN
fnp-4682	331	20	creates	create	VERB
fnp-4682	331	21	a	a	DET
fnp-4682	331	22	cellular	cellular	ADJ
fnp-4682	331	23	and	and	CCONJ
fnp-4682	331	24	molecular	molecular	ADJ
fnp-4682	331	25	environment	environment	NOUN
fnp-4682	331	26	that	that	PRON
fnp-4682	331	27	promotes	promote	VERB
fnp-4682	331	28	effective	effective	ADJ
fnp-4682	331	29	axon	axon	NOUN
fnp-4682	331	30	regeneration	regeneration	NOUN
fnp-4682	331	31	(	(	PUNCT
fnp-4682	331	32	simon	simon	PROPN
fnp-4682	331	33	and	and	CCONJ
fnp-4682	331	34	watkins	watkin	NOUN
fnp-4682	331	35	,	,	PUNCT
fnp-4682	331	36	2018	2018	NUM
fnp-4682	331	37	;	;	PUNCT
fnp-4682	331	38	li	li	PROPN
fnp-4682	331	39	et	et	PROPN
fnp-4682	331	40	al	al	PROPN
fnp-4682	331	41	.	.	PROPN
fnp-4682	331	42	,	,	PUNCT
fnp-4682	331	43	2023	2023	NUM
fnp-4682	331	44	)	)	PUNCT
fnp-4682	331	45	;	;	PUNCT
fnp-4682	331	46	therefore	therefore	ADV
fnp-4682	331	47	,	,	PUNCT
fnp-4682	331	48	inhibiting	inhibit	VERB
fnp-4682	331	49	sarm1	sarm1	PROPN
fnp-4682	331	50	activation	activation	NOUN
fnp-4682	331	51	in	in	ADP
fnp-4682	331	52	human	human	ADJ
fnp-4682	331	53	patients	patient	NOUN
fnp-4682	331	54	who	who	PRON
fnp-4682	331	55	experienced	experience	VERB
fnp-4682	331	56	traumatic	traumatic	ADJ
fnp-4682	331	57	or	or	CCONJ
fnp-4682	331	58	ischemic	ischemic	ADJ
fnp-4682	331	59	nerve	nerve	NOUN
fnp-4682	331	60	injury	injury	NOUN
fnp-4682	331	61	would	would	AUX
fnp-4682	331	62	probably	probably	ADV
fnp-4682	331	63	not	not	PART
fnp-4682	331	64	be	be	AUX
fnp-4682	331	65	beneficial	beneficial	ADJ
fnp-4682	331	66	,	,	PUNCT
fnp-4682	331	67	and	and	CCONJ
fnp-4682	331	68	might	might	AUX
fnp-4682	331	69	even	even	ADV
fnp-4682	331	70	be	be	AUX
fnp-4682	331	71	harmful	harmful	ADJ
fnp-4682	331	72	.	.	PUNCT
fnp-4682	331	73	]	]	X
fnp-4682	332	1	second	second	X
fnp-4682	332	2	,	,	PUNCT
fnp-4682	332	3	there	there	PRON
fnp-4682	332	4	should	should	AUX
fnp-4682	332	5	be	be	AUX
fnp-4682	332	6	a	a	DET
fnp-4682	332	7	continued	continue	VERB
fnp-4682	332	8	effort	effort	NOUN
fnp-4682	332	9	to	to	PART
fnp-4682	332	10	discover	discover	VERB
fnp-4682	332	11	additional	additional	ADJ
fnp-4682	332	12	sarm1	sarm1	NOUN
fnp-4682	332	13	inhibitors	inhibitor	NOUN
fnp-4682	332	14	that	that	PRON
fnp-4682	332	15	belong	belong	VERB
fnp-4682	332	16	to	to	ADP
fnp-4682	332	17	different	different	ADJ
fnp-4682	332	18	chemical	chemical	NOUN
fnp-4682	332	19	classes	class	NOUN
fnp-4682	332	20	and/or	and/or	CCONJ
fnp-4682	332	21	have	have	VERB
fnp-4682	332	22	different	different	ADJ
fnp-4682	332	23	mechanisms	mechanism	NOUN
fnp-4682	332	24	of	of	ADP
fnp-4682	332	25	action	action	NOUN
fnp-4682	332	26	.	.	PUNCT
fnp-4682	333	1	finally	finally	ADV
fnp-4682	333	2	,	,	PUNCT
fnp-4682	333	3	the	the	DET
fnp-4682	333	4	best	well	ADV
fnp-4682	333	5	performing	performing	NOUN
fnp-4682	333	6	compounds	compound	NOUN
fnp-4682	333	7	should	should	AUX
fnp-4682	333	8	rapidly	rapidly	ADV
fnp-4682	333	9	proceed	proceed	VERB
fnp-4682	333	10	to	to	ADP
fnp-4682	333	11	clinical	clinical	ADJ
fnp-4682	333	12	trials	trial	NOUN
fnp-4682	333	13	.	.	PUNCT
fnp-4682	334	1	given	give	VERB
fnp-4682	334	2	the	the	DET
fnp-4682	334	3	incredible	incredible	ADJ
fnp-4682	334	4	pace	pace	NOUN
fnp-4682	334	5	of	of	ADP
fnp-4682	334	6	research	research	NOUN
fnp-4682	334	7	in	in	ADP
fnp-4682	334	8	this	this	DET
fnp-4682	334	9	field	field	NOUN
fnp-4682	334	10	over	over	ADP
fnp-4682	334	11	the	the	DET
fnp-4682	334	12	last	last	ADJ
fnp-4682	334	13	few	few	ADJ
fnp-4682	334	14	years	year	NOUN
fnp-4682	334	15	,	,	PUNCT
fnp-4682	334	16	it	it	PRON
fnp-4682	334	17	will	will	AUX
fnp-4682	334	18	probably	probably	ADV
fnp-4682	334	19	not	not	PART
fnp-4682	334	20	take	take	VERB
fnp-4682	334	21	too	too	ADV
fnp-4682	334	22	long	long	ADV
fnp-4682	334	23	before	before	SCONJ
fnp-4682	334	24	axon	axon	NOUN
fnp-4682	334	25	-	-	PUNCT
fnp-4682	334	26	protective	protective	ADJ
fnp-4682	334	27	medications	medication	NOUN
fnp-4682	334	28	become	become	VERB
fnp-4682	334	29	available	available	ADJ
fnp-4682	334	30	for	for	ADP
fnp-4682	334	31	treatment	treatment	NOUN
fnp-4682	334	32	of	of	ADP
fnp-4682	334	33	human	human	ADJ
fnp-4682	334	34	patients	patient	NOUN
fnp-4682	334	35	with	with	ADP
fnp-4682	334	36	a	a	DET
fnp-4682	334	37	broad	broad	ADJ
fnp-4682	334	38	array	array	NOUN
fnp-4682	334	39	of	of	ADP
fnp-4682	334	40	peripheral	peripheral	ADJ
fnp-4682	334	41	–	–	PUNCT
fnp-4682	334	42	and	and	CCONJ
fnp-4682	334	43	possibly	possibly	ADV
fnp-4682	334	44	central	central	ADJ
fnp-4682	334	45	–	–	PUNCT
fnp-4682	334	46	nervous	nervous	ADJ
fnp-4682	334	47	system	system	NOUN
fnp-4682	334	48	disorders	disorder	NOUN
fnp-4682	334	49	.	.	PUNCT
fnp-4682	335	1	disclosure	disclosure	NOUN
fnp-4682	335	2	statement	statement	NOUN
fnp-4682	335	3	the	the	DET
fnp-4682	335	4	author	author	NOUN
fnp-4682	335	5	receives	receive	VERB
fnp-4682	335	6	research	research	NOUN
fnp-4682	335	7	support	support	NOUN
fnp-4682	335	8	from	from	ADP
fnp-4682	335	9	astellas	astellas	NOUN
fnp-4682	335	10	gene	gene	NOUN
fnp-4682	335	11	therapies	therapy	NOUN
fnp-4682	335	12	(	(	PUNCT
fnp-4682	335	13	formerly	formerly	ADV
fnp-4682	335	14	known	know	VERB
fnp-4682	335	15	as	as	ADP
fnp-4682	335	16	audentes	audente	NOUN
fnp-4682	335	17	therapeutics	therapeutic	NOUN
fnp-4682	335	18	,	,	PUNCT
fnp-4682	335	19	inc	inc	PROPN
fnp-4682	335	20	)	)	PUNCT
fnp-4682	335	21	as	as	ADP
fnp-4682	335	22	a	a	DET
fnp-4682	335	23	member	member	NOUN
fnp-4682	335	24	of	of	ADP
fnp-4682	335	25	the	the	DET
fnp-4682	335	26	muscle	muscle	NOUN
fnp-4682	335	27	biopsy	biopsy	PROPN
fnp-4682	335	28	review	review	PROPN
fnp-4682	335	29	committee	committee	PROPN
fnp-4682	335	30	for	for	ADP
fnp-4682	335	31	the	the	DET
fnp-4682	335	32	aspiro	aspiro	ADJ
fnp-4682	335	33	(	(	PUNCT
fnp-4682	335	34	nct03199469	nct03199469	ADJ
fnp-4682	335	35	)	)	PUNCT
fnp-4682	335	36	and	and	CCONJ
fnp-4682	335	37	fortis	fortis	PROPN
fnp-4682	335	38	(	(	PUNCT
fnp-4682	335	39	nct04174105	nct04174105	NOUN
fnp-4682	335	40	)	)	PUNCT
fnp-4682	335	41	clinical	clinical	ADJ
fnp-4682	335	42	trials	trial	NOUN
fnp-4682	335	43	,	,	PUNCT
fnp-4682	335	44	which	which	PRON
fnp-4682	335	45	are	be	AUX
fnp-4682	335	46	evaluating	evaluate	VERB
fnp-4682	335	47	the	the	DET
fnp-4682	335	48	safety	safety	NOUN
fnp-4682	335	49	and	and	CCONJ
fnp-4682	335	50	efficacy	efficacy	NOUN
fnp-4682	335	51	of	of	ADP
fnp-4682	335	52	gene	gene	NOUN
fnp-4682	335	53	transfer	transfer	NOUN
fnp-4682	335	54	therapy	therapy	NOUN
fnp-4682	335	55	for	for	ADP
fnp-4682	335	56	x	x	ADV
fnp-4682	335	57	-	-	VERB
fnp-4682	335	58	linked	link	VERB
fnp-4682	335	59	myotubular	myotubular	ADJ
fnp-4682	335	60	myopathy	myopathy	ADJ
fnp-4682	335	61	(	(	PUNCT
fnp-4682	335	62	aspiro	aspiro	ADJ
fnp-4682	335	63	)	)	PUNCT
fnp-4682	335	64	and	and	CCONJ
fnp-4682	335	65	late	late	ADJ
fnp-4682	335	66	onset	onset	ADJ
fnp-4682	335	67	pompe	pompe	PROPN
fnp-4682	335	68	disease	disease	NOUN
fnp-4682	335	69	(	(	PUNCT
fnp-4682	335	70	fortis	fortis	PROPN
fnp-4682	335	71	)	)	PUNCT
fnp-4682	335	72	.	.	PUNCT
fnp-4682	336	1	acknowledgements	acknowledgement	NOUN
fnp-4682	336	2	i	i	PRON
fnp-4682	336	3	am	be	AUX
fnp-4682	336	4	grateful	grateful	ADJ
fnp-4682	336	5	to	to	PART
fnp-4682	336	6	drs	drs	PROPN
fnp-4682	336	7	.	.	PUNCT
fnp-4682	337	1	nigel	nigel	PROPN
fnp-4682	337	2	g.	g.	PROPN
fnp-4682	337	3	laing	laing	PROPN
fnp-4682	337	4	,	,	PUNCT
fnp-4682	337	5	gina	gina	PROPN
fnp-4682	337	6	ravenscroft	ravenscroft	PROPN
fnp-4682	337	7	,	,	PUNCT
fnp-4682	337	8	and	and	CCONJ
fnp-4682	337	9	benedikt	benedikt	NOUN
fnp-4682	337	10	schoser	schoser	NOUN
fnp-4682	337	11	for	for	ADP
fnp-4682	337	12	helpful	helpful	ADJ
fnp-4682	337	13	input	input	NOUN
fnp-4682	337	14	during	during	ADP
fnp-4682	337	15	the	the	DET
fnp-4682	337	16	conceptualization	conceptualization	NOUN
fnp-4682	337	17	stage	stage	NOUN
fnp-4682	337	18	of	of	ADP
fnp-4682	337	19	this	this	DET
fnp-4682	337	20	review	review	NOUN
fnp-4682	337	21	.	.	PUNCT
fnp-4682	338	1	in	in	ADP
fnp-4682	338	2	addition	addition	NOUN
fnp-4682	338	3	,	,	PUNCT
fnp-4682	338	4	i	i	PRON
fnp-4682	338	5	would	would	AUX
fnp-4682	338	6	like	like	VERB
fnp-4682	338	7	to	to	PART
fnp-4682	338	8	thank	thank	VERB
fnp-4682	338	9	ms	ms	PROPN
fnp-4682	338	10	.	.	PROPN
fnp-4682	338	11	christine	christine	PROPN
fnp-4682	338	12	lin	lin	PROPN
fnp-4682	338	13	for	for	ADP
fnp-4682	338	14	assistance	assistance	NOUN
fnp-4682	338	15	with	with	ADP
fnp-4682	338	16	figure	figure	NOUN
fnp-4682	338	17	preparation	preparation	NOUN
fnp-4682	338	18	.	.	PUNCT
fnp-4682	339	1	references	reference	NOUN
fnp-4682	339	2	abrams	abrams	PROPN
fnp-4682	339	3	,	,	PUNCT
fnp-4682	339	4	r.m.c	r.m.c	PROPN
fnp-4682	339	5	.	.	PROPN
fnp-4682	339	6	,	,	PUNCT
fnp-4682	339	7	simpson	simpson	PROPN
fnp-4682	339	8	,	,	PUNCT
fnp-4682	339	9	d.m	d.m	PROPN
fnp-4682	339	10	.	.	PROPN
fnp-4682	339	11	,	,	PUNCT
fnp-4682	339	12	navis	navis	PROPN
fnp-4682	339	13	,	,	PUNCT
fnp-4682	339	14	a.	a.	PROPN
fnp-4682	339	15	,	,	PUNCT
fnp-4682	339	16	jette	jette	PROPN
fnp-4682	339	17	,	,	PUNCT
fnp-4682	339	18	n.	n.	NOUN
fnp-4682	339	19	,	,	PUNCT
fnp-4682	339	20	zhou	zhou	PROPN
fnp-4682	339	21	,	,	PUNCT
fnp-4682	339	22	l.	l.	PROPN
fnp-4682	339	23	,	,	PUNCT
fnp-4682	339	24	and	and	CCONJ
fnp-4682	339	25	shin	shin	NOUN
fnp-4682	339	26	,	,	PUNCT
fnp-4682	339	27	s.c	s.c	PROPN
fnp-4682	339	28	.	.	PROPN
fnp-4682	339	29	(	(	PUNCT
fnp-4682	339	30	2022	2022	NUM
fnp-4682	339	31	)	)	PUNCT
fnp-4682	339	32	.	.	PUNCT
fnp-4682	340	1	small	small	ADJ
fnp-4682	340	2	fiber	fiber	NOUN
fnp-4682	340	3	neuropathy	neuropathy	ADV
fnp-4682	340	4	associated	associate	VERB
fnp-4682	340	5	with	with	ADP
fnp-4682	340	6	sars	sar	NOUN
fnp-4682	340	7	-	-	PUNCT
fnp-4682	340	8	cov-2	cov-2	PART
fnp-4682	340	9	infection	infection	NOUN
fnp-4682	340	10	.	.	PUNCT
fnp-4682	341	1	muscle	muscle	NOUN
fnp-4682	341	2	nerve	nerve	NOUN
fnp-4682	341	3	65	65	NUM
fnp-4682	341	4	,	,	PUNCT
fnp-4682	341	5	440	440	NUM
fnp-4682	341	6	-	-	SYM
fnp-4682	341	7	443	443	NUM
fnp-4682	341	8	.	.	PUNCT
fnp-4682	342	1	https://doi.org/10.1002/mus.27458	https://doi.org/10.1002/mus.27458	PROPN
fnp-4682	342	2	bloom	bloom	NOUN
fnp-4682	342	3	,	,	PUNCT
fnp-4682	342	4	a.j	a.j	PROPN
fnp-4682	342	5	.	.	PROPN
fnp-4682	342	6	,	,	PUNCT
fnp-4682	342	7	mao	mao	PROPN
fnp-4682	342	8	,	,	PUNCT
fnp-4682	342	9	x.	x.	PROPN
fnp-4682	342	10	,	,	PUNCT
fnp-4682	342	11	strickland	strickland	PROPN
fnp-4682	342	12	,	,	PUNCT
fnp-4682	342	13	a.	a.	PROPN
fnp-4682	342	14	,	,	PUNCT
fnp-4682	342	15	sasaki	sasaki	PROPN
fnp-4682	342	16	,	,	PUNCT
fnp-4682	342	17	y.	y.	PROPN
fnp-4682	342	18	,	,	PUNCT
fnp-4682	342	19	milbrandt	milbrandt	PROPN
fnp-4682	342	20	,	,	PUNCT
fnp-4682	342	21	j.	j.	PROPN
fnp-4682	342	22	,	,	PUNCT
fnp-4682	342	23	and	and	CCONJ
fnp-4682	342	24	diantonio	diantonio	NOUN
fnp-4682	342	25	,	,	PUNCT
fnp-4682	342	26	a.	a.	NOUN
fnp-4682	342	27	(	(	PUNCT
fnp-4682	342	28	2022	2022	NUM
fnp-4682	342	29	)	)	PUNCT
fnp-4682	342	30	.	.	PUNCT
fnp-4682	343	1	constitutively	constitutively	ADV
fnp-4682	343	2	active	active	ADJ
fnp-4682	343	3	sarm1	sarm1	PUNCT
fnp-4682	343	4	variants	variant	NOUN
fnp-4682	343	5	that	that	PRON
fnp-4682	343	6	induce	induce	VERB
fnp-4682	343	7	neuropathy	neuropathy	ADJ
fnp-4682	343	8	are	be	AUX
fnp-4682	343	9	enriched	enrich	VERB
fnp-4682	343	10	in	in	ADP
fnp-4682	343	11	als	als	NOUN
fnp-4682	343	12	patients	patient	NOUN
fnp-4682	343	13	.	.	PUNCT
fnp-4682	344	1	mol	mol	ADP
fnp-4682	344	2	neurodegener	neurodegener	NOUN
fnp-4682	344	3	17	17	NUM
fnp-4682	344	4	,	,	PUNCT
fnp-4682	344	5	1	1	NUM
fnp-4682	344	6	.	.	X
fnp-4682	344	7	https://doi.org/10.1186/s13024-021-00511-x	https://doi.org/10.1186/s13024-021-00511-x	PROPN
fnp-4682	344	8	blume	blume	PROPN
fnp-4682	344	9	,	,	PUNCT
fnp-4682	344	10	g.	g.	PROPN
fnp-4682	344	11	,	,	PUNCT
fnp-4682	344	12	pestronk	pestronk	PROPN
fnp-4682	344	13	,	,	PUNCT
fnp-4682	344	14	a.	a.	NOUN
fnp-4682	344	15	,	,	PUNCT
fnp-4682	344	16	frank	frank	PROPN
fnp-4682	344	17	,	,	PUNCT
fnp-4682	344	18	b.	b.	PROPN
fnp-4682	344	19	,	,	PUNCT
fnp-4682	344	20	and	and	CCONJ
fnp-4682	344	21	johns	johns	PROPN
fnp-4682	344	22	,	,	PUNCT
fnp-4682	344	23	d.r	d.r	PROPN
fnp-4682	344	24	.	.	PROPN
fnp-4682	344	25	(	(	PUNCT
fnp-4682	344	26	1997	1997	NUM
fnp-4682	344	27	)	)	PUNCT
fnp-4682	344	28	.	.	PUNCT
fnp-4682	345	1	polymyositis	polymyositis	PROPN
fnp-4682	345	2	with	with	ADP
fnp-4682	345	3	cytochrome	cytochrome	ADJ
fnp-4682	345	4	oxidase	oxidase	NOUN
fnp-4682	345	5	negative	negative	ADJ
fnp-4682	345	6	muscle	muscle	NOUN
fnp-4682	345	7	fibres	fibre	NOUN
fnp-4682	345	8	.	.	PUNCT
fnp-4682	346	1	early	early	ADJ
fnp-4682	346	2	quadriceps	quadricep	NOUN
fnp-4682	346	3	weakness	weakness	NOUN
fnp-4682	346	4	and	and	CCONJ
fnp-4682	346	5	poor	poor	ADJ
fnp-4682	346	6	response	response	NOUN
fnp-4682	346	7	to	to	ADP
fnp-4682	346	8	immunosuppressive	immunosuppressive	ADJ
fnp-4682	346	9	therapy	therapy	NOUN
fnp-4682	346	10	.	.	PUNCT
fnp-4682	347	1	brain	brain	NOUN
fnp-4682	347	2	120	120	NUM
fnp-4682	347	3	,	,	PUNCT
fnp-4682	347	4	39	39	NUM
fnp-4682	347	5	-	-	SYM
fnp-4682	347	6	45	45	NUM
fnp-4682	347	7	.	.	PUNCT
fnp-4682	348	1	https://doi.org/10.1093/brain/120.1.39	https://doi.org/10.1093/brain/120.1.39	NOUN
fnp-4682	348	2	bosanac	bosanac	NOUN
fnp-4682	348	3	,	,	PUNCT
fnp-4682	348	4	t.	t.	PROPN
fnp-4682	348	5	,	,	PUNCT
fnp-4682	348	6	hughes	hughes	PROPN
fnp-4682	348	7	,	,	PUNCT
fnp-4682	348	8	r.o	r.o	PROPN
fnp-4682	348	9	.	.	PROPN
fnp-4682	348	10	,	,	PUNCT
fnp-4682	348	11	engber	engber	PROPN
fnp-4682	348	12	,	,	PUNCT
fnp-4682	348	13	t.	t.	PROPN
fnp-4682	348	14	,	,	PUNCT
fnp-4682	348	15	devraj	devraj	PROPN
fnp-4682	348	16	,	,	PUNCT
fnp-4682	348	17	r.	r.	PROPN
fnp-4682	348	18	,	,	PUNCT
fnp-4682	348	19	brearley	brearley	ADV
fnp-4682	348	20	,	,	PUNCT
fnp-4682	348	21	a.	a.	NOUN
fnp-4682	348	22	,	,	PUNCT
fnp-4682	348	23	danker	danker	PROPN
fnp-4682	348	24	,	,	PUNCT
fnp-4682	348	25	k.	k.	PROPN
fnp-4682	348	26	,	,	PUNCT
fnp-4682	348	27	young	young	PROPN
fnp-4682	348	28	,	,	PUNCT
fnp-4682	348	29	k.	k.	PROPN
fnp-4682	348	30	,	,	PUNCT
fnp-4682	348	31	kopatz	kopatz	PROPN
fnp-4682	348	32	,	,	PUNCT
fnp-4682	348	33	j.	j.	PROPN
fnp-4682	348	34	,	,	PUNCT
fnp-4682	348	35	hermann	hermann	PROPN
fnp-4682	348	36	,	,	PUNCT
fnp-4682	348	37	m.	m.	NOUN
fnp-4682	348	38	,	,	PUNCT
fnp-4682	348	39	berthemy	berthemy	NOUN
fnp-4682	348	40	,	,	PUNCT
fnp-4682	348	41	a.	a.	PROPN
fnp-4682	348	42	,	,	PUNCT
fnp-4682	348	43	et	et	PROPN
fnp-4682	348	44	al	al	PROPN
fnp-4682	348	45	.	.	PROPN
fnp-4682	348	46	(	(	PUNCT
fnp-4682	348	47	2021	2021	NUM
fnp-4682	348	48	)	)	PUNCT
fnp-4682	348	49	.	.	PUNCT
fnp-4682	349	1	pharmacological	pharmacological	ADJ
fnp-4682	349	2	sarm1	sarm1	PROPN
fnp-4682	349	3	inhibition	inhibition	NOUN
fnp-4682	349	4	protects	protect	VERB
fnp-4682	349	5	axon	axon	NOUN
fnp-4682	349	6	structure	structure	NOUN
fnp-4682	349	7	and	and	CCONJ
fnp-4682	349	8	function	function	NOUN
fnp-4682	349	9	in	in	ADP
fnp-4682	349	10	paclitaxel	paclitaxel	NOUN
fnp-4682	349	11	-	-	PUNCT
fnp-4682	349	12	induced	induce	VERB
fnp-4682	349	13	peripheral	peripheral	ADJ
fnp-4682	349	14	neuropathy	neuropathy	ADJ
fnp-4682	349	15	.	.	PUNCT
fnp-4682	350	1	brain	brain	NOUN
fnp-4682	350	2	144	144	NUM
fnp-4682	350	3	,	,	PUNCT
fnp-4682	350	4	3226	3226	NUM
fnp-4682	350	5	-	-	SYM
fnp-4682	350	6	3238	3238	NUM
fnp-4682	350	7	.	.	PUNCT
fnp-4682	351	1	https://doi.org/10.1093/brain/awab184	https://doi.org/10.1093/brain/awab184	NOUN
fnp-4682	351	2	bratkowski	bratkowski	NOUN
fnp-4682	351	3	,	,	PUNCT
fnp-4682	351	4	m.	m.	NOUN
fnp-4682	351	5	,	,	PUNCT
fnp-4682	351	6	burdett	burdett	PROPN
fnp-4682	351	7	,	,	PUNCT
fnp-4682	351	8	t.c	t.c	PROPN
fnp-4682	351	9	.	.	PROPN
fnp-4682	351	10	,	,	PUNCT
fnp-4682	351	11	danao	danao	PROPN
fnp-4682	351	12	,	,	PUNCT
fnp-4682	351	13	j.	j.	PROPN
fnp-4682	351	14	,	,	PUNCT
fnp-4682	351	15	wang	wang	PROPN
fnp-4682	351	16	,	,	PUNCT
fnp-4682	351	17	x.	x.	PROPN
fnp-4682	351	18	,	,	PUNCT
fnp-4682	351	19	mathur	mathur	PROPN
fnp-4682	351	20	,	,	PUNCT
fnp-4682	351	21	p.	p.	PROPN
fnp-4682	351	22	,	,	PUNCT
fnp-4682	351	23	gu	gu	PROPN
fnp-4682	351	24	,	,	PUNCT
fnp-4682	351	25	w.	w.	PROPN
fnp-4682	351	26	,	,	PUNCT
fnp-4682	351	27	beckstead	beckstead	NOUN
fnp-4682	351	28	,	,	PUNCT
fnp-4682	351	29	j.a	j.a	PROPN
fnp-4682	351	30	.	.	PROPN
fnp-4682	351	31	,	,	PUNCT
fnp-4682	351	32	talreja	talreja	PROPN
fnp-4682	351	33	,	,	PUNCT
fnp-4682	351	34	s.	s.	PROPN
fnp-4682	351	35	,	,	PUNCT
fnp-4682	351	36	yang	yang	PROPN
fnp-4682	351	37	,	,	PUNCT
fnp-4682	351	38	y.s	y.s	PROPN
fnp-4682	351	39	.	.	PROPN
fnp-4682	351	40	,	,	PUNCT
fnp-4682	351	41	danko	danko	PROPN
fnp-4682	351	42	,	,	PUNCT
fnp-4682	351	43	g.	g.	PROPN
fnp-4682	351	44	,	,	PUNCT
fnp-4682	351	45	et	et	PROPN
fnp-4682	351	46	al	al	PROPN
fnp-4682	351	47	.	.	PROPN
fnp-4682	351	48	(	(	PUNCT
fnp-4682	351	49	2022	2022	NUM
fnp-4682	351	50	)	)	PUNCT
fnp-4682	351	51	.	.	PUNCT
fnp-4682	352	1	uncompetitive	uncompetitive	ADJ
fnp-4682	352	2	,	,	PUNCT
fnp-4682	352	3	adduct	adduct	NOUN
fnp-4682	352	4	-	-	PUNCT
fnp-4682	352	5	forming	form	VERB
fnp-4682	352	6	sarm1	sarm1	NOUN
fnp-4682	353	1	inhibitors	inhibitor	NOUN
fnp-4682	353	2	are	be	AUX
fnp-4682	353	3	neuroprotective	neuroprotective	ADJ
fnp-4682	353	4	in	in	ADP
fnp-4682	353	5	preclinical	preclinical	ADJ
fnp-4682	353	6	models	model	NOUN
fnp-4682	353	7	of	of	ADP
fnp-4682	353	8	nerve	nerve	NOUN
fnp-4682	353	9	injury	injury	NOUN
fnp-4682	353	10	and	and	CCONJ
fnp-4682	353	11	disease	disease	NOUN
fnp-4682	353	12	.	.	PUNCT
fnp-4682	353	13	neuron	neuron	PROPN
fnp-4682	353	14	110	110	NUM
fnp-4682	353	15	,	,	PUNCT
fnp-4682	353	16	3711	3711	NUM
fnp-4682	353	17	-	-	SYM
fnp-4682	353	18	3726	3726	NUM
fnp-4682	353	19	.	.	PUNCT
fnp-4682	354	1	https://doi.org/10.1016/j.neuron.2022.08.017	https://doi.org/10.1016/j.neuron.2022.08.017	X
fnp-4682	354	2	britson	britson	PROPN
fnp-4682	354	3	,	,	PUNCT
fnp-4682	354	4	k.a	k.a	PROPN
fnp-4682	354	5	.	.	PROPN
fnp-4682	354	6	,	,	PUNCT
fnp-4682	354	7	ling	ling	PROPN
fnp-4682	354	8	,	,	PUNCT
fnp-4682	354	9	j.p	j.p	PROPN
fnp-4682	354	10	.	.	PROPN
fnp-4682	354	11	,	,	PUNCT
fnp-4682	354	12	braunstein	braunstein	PROPN
fnp-4682	354	13	,	,	PUNCT
fnp-4682	354	14	k.e	k.e	PROPN
fnp-4682	354	15	.	.	PROPN
fnp-4682	354	16	,	,	PUNCT
fnp-4682	354	17	montagne	montagne	PROPN
fnp-4682	354	18	,	,	PUNCT
fnp-4682	354	19	j.m	j.m	PROPN
fnp-4682	354	20	.	.	PROPN
fnp-4682	354	21	,	,	PUNCT
fnp-4682	354	22	kastenschmidt	kastenschmidt	PROPN
fnp-4682	354	23	,	,	PUNCT
fnp-4682	354	24	j.m	j.m	PROPN
fnp-4682	354	25	.	.	PROPN
fnp-4682	354	26	,	,	PUNCT
fnp-4682	354	27	wilson	wilson	PROPN
fnp-4682	354	28	,	,	PUNCT
fnp-4682	354	29	a.	a.	PROPN
fnp-4682	354	30	,	,	PUNCT
fnp-4682	354	31	ikenaga	ikenaga	PROPN
fnp-4682	354	32	,	,	PUNCT
fnp-4682	354	33	c.	c.	NOUN
fnp-4682	354	34	,	,	PUNCT
fnp-4682	354	35	tsao	tsao	PROPN
fnp-4682	354	36	,	,	PUNCT
fnp-4682	354	37	w.	w.	PROPN
fnp-4682	354	38	,	,	PUNCT
fnp-4682	354	39	pinal	pinal	PROPN
fnp-4682	354	40	-	-	PUNCT
fnp-4682	354	41	fernandez	fernandez	PROPN
fnp-4682	354	42	,	,	PUNCT
fnp-4682	354	43	i.	i.	PROPN
fnp-4682	354	44	,	,	PUNCT
fnp-4682	354	45	russell	russell	PROPN
fnp-4682	354	46	,	,	PUNCT
fnp-4682	354	47	k.a	k.a	PROPN
fnp-4682	354	48	.	.	PROPN
fnp-4682	354	49	,	,	PUNCT
fnp-4682	354	50	et	et	PROPN
fnp-4682	354	51	al	al	PROPN
fnp-4682	354	52	.	.	PROPN
fnp-4682	354	53	(	(	PUNCT
fnp-4682	354	54	2022	2022	NUM
fnp-4682	354	55	)	)	PUNCT
fnp-4682	354	56	.	.	PUNCT
fnp-4682	355	1	loss	loss	NOUN
fnp-4682	355	2	of	of	ADP
fnp-4682	355	3	tdp-43	tdp-43	NOUN
fnp-4682	355	4	function	function	NOUN
fnp-4682	355	5	and	and	CCONJ
fnp-4682	355	6	rimmed	rimmed	ADJ
fnp-4682	355	7	vacuoles	vacuole	NOUN
fnp-4682	355	8	persist	persist	VERB
fnp-4682	355	9	after	after	ADP
fnp-4682	355	10	t	t	PROPN
fnp-4682	355	11	cell	cell	NOUN
fnp-4682	355	12	depletion	depletion	NOUN
fnp-4682	355	13	in	in	ADP
fnp-4682	355	14	a	a	DET
fnp-4682	355	15	xenograft	xenograft	NOUN
fnp-4682	355	16	model	model	NOUN
fnp-4682	355	17	of	of	ADP
fnp-4682	355	18	sporadic	sporadic	ADJ
fnp-4682	355	19	inclusion	inclusion	NOUN
fnp-4682	355	20	body	body	NOUN
fnp-4682	355	21	myositis	myositis	NOUN
fnp-4682	355	22	.	.	PUNCT
fnp-4682	356	1	sci	sci	PROPN
fnp-4682	356	2	transl	transl	PROPN
fnp-4682	356	3	med	me	VERB
fnp-4682	356	4	14	14	NUM
fnp-4682	356	5	,	,	PUNCT
fnp-4682	356	6	eabi9196	eabi9196	PROPN
fnp-4682	356	7	.	.	PUNCT
fnp-4682	357	1	https://doi.org/10.1126/scitranslmed.abi9196	https://doi.org/10.1126/scitranslmed.abi9196	PROPN
fnp-4682	357	2	conforti	conforti	PROPN
fnp-4682	357	3	,	,	PUNCT
fnp-4682	357	4	l.	l.	PROPN
fnp-4682	357	5	,	,	PUNCT
fnp-4682	357	6	gilley	gilley	PROPN
fnp-4682	357	7	,	,	PUNCT
fnp-4682	357	8	j.	j.	PROPN
fnp-4682	357	9	,	,	PUNCT
fnp-4682	357	10	and	and	CCONJ
fnp-4682	357	11	coleman	coleman	PROPN
fnp-4682	357	12	,	,	PUNCT
fnp-4682	357	13	m.p	m.p	PROPN
fnp-4682	357	14	.	.	PROPN
fnp-4682	357	15	(	(	PUNCT
fnp-4682	357	16	2014	2014	NUM
fnp-4682	357	17	)	)	PUNCT
fnp-4682	357	18	.	.	PUNCT
fnp-4682	358	1	wallerian	wallerian	ADJ
fnp-4682	358	2	degeneration	degeneration	NOUN
fnp-4682	358	3	:	:	PUNCT
fnp-4682	358	4	an	an	DET
fnp-4682	358	5	emerging	emerge	VERB
fnp-4682	358	6	axon	axon	NOUN
fnp-4682	358	7	death	death	NOUN
fnp-4682	358	8	pathway	pathway	NOUN
fnp-4682	358	9	linking	link	VERB
fnp-4682	358	10	injury	injury	NOUN
fnp-4682	358	11	and	and	CCONJ
fnp-4682	358	12	disease	disease	NOUN
fnp-4682	358	13	.	.	PUNCT
fnp-4682	359	1	nat	nat	PROPN
fnp-4682	359	2	rev	rev	VERB
fnp-4682	359	3	neurosci	neurosci	PROPN
fnp-4682	359	4	15	15	NUM
fnp-4682	359	5	,	,	PUNCT
fnp-4682	359	6	394	394	NUM
fnp-4682	359	7	-	-	SYM
fnp-4682	359	8	409	409	NUM
fnp-4682	359	9	.	.	PUNCT
fnp-4682	360	1	https://doi.org/10.1038/nrn3680	https://doi.org/10.1038/nrn3680	ADV
fnp-4682	360	2	cummings	cummings	PROPN
fnp-4682	360	3	,	,	PUNCT
fnp-4682	360	4	b.b	b.b	PROPN
fnp-4682	360	5	.	.	PROPN
fnp-4682	360	6	,	,	PUNCT
fnp-4682	360	7	marshall	marshall	PROPN
fnp-4682	360	8	,	,	PUNCT
fnp-4682	360	9	j.l	j.l	PROPN
fnp-4682	360	10	.	.	PROPN
fnp-4682	360	11	,	,	PUNCT
fnp-4682	360	12	tukiainen	tukiainen	PROPN
fnp-4682	360	13	,	,	PUNCT
fnp-4682	360	14	t.	t.	PROPN
fnp-4682	360	15	,	,	PUNCT
fnp-4682	360	16	lek	lek	PROPN
fnp-4682	360	17	,	,	PUNCT
fnp-4682	360	18	m.	m.	NOUN
fnp-4682	360	19	,	,	PUNCT
fnp-4682	360	20	donkervoort	donkervoort	NOUN
fnp-4682	360	21	,	,	PUNCT
fnp-4682	360	22	s.	s.	PROPN
fnp-4682	360	23	,	,	PUNCT
fnp-4682	360	24	foley	foley	PROPN
fnp-4682	360	25	,	,	PUNCT
fnp-4682	360	26	a.r	a.r	PROPN
fnp-4682	360	27	.	.	PROPN
fnp-4682	360	28	,	,	PUNCT
fnp-4682	360	29	bolduc	bolduc	PROPN
fnp-4682	360	30	,	,	PUNCT
fnp-4682	360	31	v.	v.	PROPN
fnp-4682	360	32	,	,	PUNCT
fnp-4682	360	33	waddell	waddell	PROPN
fnp-4682	360	34	,	,	PUNCT
fnp-4682	360	35	l.b	l.b	PROPN
fnp-4682	360	36	.	.	PROPN
fnp-4682	360	37	,	,	PUNCT
fnp-4682	360	38	sandaradura	sandaradura	PROPN
fnp-4682	360	39	,	,	PUNCT
fnp-4682	360	40	s.a	s.a	PROPN
fnp-4682	360	41	.	.	PROPN
fnp-4682	360	42	,	,	PUNCT
fnp-4682	360	43	o'grady	o'grady	PROPN
fnp-4682	360	44	,	,	PUNCT
fnp-4682	360	45	g.l	g.l	PROPN
fnp-4682	360	46	.	.	PROPN
fnp-4682	360	47	,	,	PUNCT
fnp-4682	360	48	et	et	PROPN
fnp-4682	360	49	al	al	PROPN
fnp-4682	360	50	.	.	PUNCT
fnp-4682	360	51	(	(	PUNCT
fnp-4682	360	52	2017	2017	NUM
fnp-4682	360	53	)	)	PUNCT
fnp-4682	360	54	.	.	PUNCT
fnp-4682	361	1	improving	improve	VERB
fnp-4682	361	2	genetic	genetic	ADJ
fnp-4682	361	3	diagnosis	diagnosis	NOUN
fnp-4682	361	4	in	in	ADP
fnp-4682	361	5	mendelian	mendelian	ADJ
fnp-4682	361	6	disease	disease	NOUN
fnp-4682	361	7	with	with	ADP
fnp-4682	361	8	transcriptome	transcriptome	ADJ
fnp-4682	361	9	sequencing	sequencing	NOUN
fnp-4682	361	10	.	.	PUNCT
fnp-4682	362	1	sci	sci	PROPN
fnp-4682	362	2	transl	transl	PROPN
fnp-4682	362	3	med	me	VERB
fnp-4682	362	4	9	9	NUM
fnp-4682	362	5	,	,	PUNCT
fnp-4682	362	6	eaal5209	eaal5209	PROPN
fnp-4682	362	7	.	.	PUNCT
fnp-4682	363	1	https://doi.org/10.1126/scitranslmed.aal5209	https://doi.org/10.1126/scitranslmed.aal5209	PROPN
fnp-4682	363	2	de	de	PROPN
fnp-4682	363	3	reuck	reuck	PROPN
fnp-4682	363	4	,	,	PUNCT
fnp-4682	363	5	j.	j.	PROPN
fnp-4682	363	6	,	,	PUNCT
fnp-4682	363	7	de	de	PROPN
fnp-4682	363	8	coster	coster	PROPN
fnp-4682	363	9	,	,	PUNCT
fnp-4682	363	10	w.	w.	PROPN
fnp-4682	363	11	,	,	PUNCT
fnp-4682	363	12	and	and	CCONJ
fnp-4682	363	13	vander	vander	PROPN
fnp-4682	363	14	eecken	eecken	VERB
fnp-4682	363	15	,	,	PUNCT
fnp-4682	363	16	h.	h.	PROPN
fnp-4682	363	17	(	(	PUNCT
fnp-4682	363	18	1977	1977	NUM
fnp-4682	363	19	)	)	PUNCT
fnp-4682	363	20	.	.	PUNCT
fnp-4682	364	1	the	the	DET
fnp-4682	364	2	target	target	NOUN
fnp-4682	364	3	phenomenon	phenomenon	NOUN
fnp-4682	364	4	in	in	ADP
fnp-4682	364	5	rat	rat	NOUN
fnp-4682	364	6	muscle	muscle	NOUN
fnp-4682	364	7	following	follow	VERB
fnp-4682	364	8	tenotomy	tenotomy	NOUN
fnp-4682	364	9	and	and	CCONJ
fnp-4682	364	10	neurotomy	neurotomy	NOUN
fnp-4682	364	11	.	.	PUNCT
fnp-4682	365	1	a	a	DET
fnp-4682	365	2	comparative	comparative	ADJ
fnp-4682	365	3	light	light	NOUN
fnp-4682	365	4	microscopic	microscopic	ADJ
fnp-4682	365	5	and	and	CCONJ
fnp-4682	365	6	histochemical	histochemical	ADJ
fnp-4682	365	7	study	study	NOUN
fnp-4682	365	8	.	.	PUNCT
fnp-4682	366	1	acta	acta	PROPN
fnp-4682	366	2	neuropathol	neuropathol	PROPN
fnp-4682	366	3	37	37	NUM
fnp-4682	366	4	,	,	PUNCT
fnp-4682	366	5	49	49	NUM
fnp-4682	366	6	-	-	SYM
fnp-4682	366	7	53	53	NUM
fnp-4682	366	8	.	.	PUNCT
fnp-4682	367	1	https://doi.org/10.1007/bf00684540	https://doi.org/10.1007/bf00684540	X
fnp-4682	367	2	dingwall	dingwall	PROPN
fnp-4682	367	3	,	,	PUNCT
fnp-4682	367	4	c.b	c.b	PROPN
fnp-4682	367	5	.	.	PROPN
fnp-4682	367	6	,	,	PUNCT
fnp-4682	367	7	strickland	strickland	PROPN
fnp-4682	367	8	,	,	PUNCT
fnp-4682	367	9	a.	a.	PROPN
fnp-4682	367	10	,	,	PUNCT
fnp-4682	367	11	yum	yum	PROPN
fnp-4682	367	12	,	,	PUNCT
fnp-4682	367	13	s.w	s.w	PROPN
fnp-4682	367	14	.	.	PROPN
fnp-4682	367	15	,	,	PUNCT
fnp-4682	367	16	yim	yim	PROPN
fnp-4682	367	17	,	,	PUNCT
fnp-4682	367	18	a.k	a.k	PROPN
fnp-4682	367	19	.	.	PROPN
fnp-4682	367	20	,	,	PUNCT
fnp-4682	367	21	zhu	zhu	PROPN
fnp-4682	367	22	,	,	PUNCT
fnp-4682	367	23	j.	j.	PROPN
fnp-4682	367	24	,	,	PUNCT
fnp-4682	367	25	wang	wang	PROPN
fnp-4682	367	26	,	,	PUNCT
fnp-4682	367	27	p.l	p.l	PROPN
fnp-4682	367	28	.	.	PROPN
fnp-4682	367	29	,	,	PUNCT
fnp-4682	367	30	yamada	yamada	PROPN
fnp-4682	367	31	,	,	PUNCT
fnp-4682	367	32	y.	y.	PROPN
fnp-4682	367	33	,	,	PUNCT
fnp-4682	367	34	schmidt	schmidt	PROPN
fnp-4682	367	35	,	,	PUNCT
fnp-4682	367	36	r.e	r.e	PROPN
fnp-4682	367	37	.	.	PROPN
fnp-4682	367	38	,	,	PUNCT
fnp-4682	367	39	sasaki	sasaki	PROPN
fnp-4682	367	40	,	,	PUNCT
fnp-4682	367	41	y.	y.	PROPN
fnp-4682	367	42	,	,	PUNCT
fnp-4682	367	43	bloom	bloom	NOUN
fnp-4682	367	44	,	,	PUNCT
fnp-4682	367	45	a.j	a.j	PROPN
fnp-4682	367	46	.	.	PROPN
fnp-4682	367	47	,	,	PUNCT
fnp-4682	367	48	et	et	PROPN
fnp-4682	367	49	al	al	PROPN
fnp-4682	367	50	.	.	PROPN
fnp-4682	367	51	(	(	PUNCT
fnp-4682	367	52	2022	2022	NUM
fnp-4682	367	53	)	)	PUNCT
fnp-4682	367	54	.	.	PUNCT
fnp-4682	368	1	macrophage	macrophage	ADJ
fnp-4682	368	2	depletion	depletion	NOUN
fnp-4682	368	3	blocks	block	NOUN
fnp-4682	368	4	congenital	congenital	ADJ
fnp-4682	368	5	sarm1	sarm1	NOUN
fnp-4682	368	6	-	-	PUNCT
fnp-4682	368	7	dependent	dependent	ADJ
fnp-4682	368	8	neuropathy	neuropathy	ADJ
fnp-4682	368	9	.	.	PUNCT
fnp-4682	369	1	j	j	PROPN
fnp-4682	369	2	clin	clin	PROPN
fnp-4682	369	3	invest	invest	VERB
fnp-4682	369	4	132	132	NUM
fnp-4682	369	5	,	,	PUNCT
fnp-4682	369	6	e159800	e159800	NOUN
fnp-4682	369	7	.	.	PUNCT
fnp-4682	370	1	https://doi.org/10.1172/jci159800	https://doi.org/10.1172/jci159800	PROPN
fnp-4682	370	2	engel	engel	PROPN
fnp-4682	370	3	,	,	PUNCT
fnp-4682	370	4	w.k	w.k	PROPN
fnp-4682	370	5	.	.	PROPN
fnp-4682	370	6	(	(	PUNCT
fnp-4682	370	7	1961	1961	NUM
fnp-4682	370	8	)	)	PUNCT
fnp-4682	370	9	.	.	PUNCT
fnp-4682	371	1	muscle	muscle	NOUN
fnp-4682	371	2	target	target	NOUN
fnp-4682	371	3	fibres	fibre	NOUN
fnp-4682	371	4	,	,	PUNCT
fnp-4682	371	5	a	a	DET
fnp-4682	371	6	newly	newly	ADV
fnp-4682	371	7	recognized	recognize	VERB
fnp-4682	371	8	sign	sign	NOUN
fnp-4682	371	9	of	of	ADP
fnp-4682	371	10	denervation	denervation	NOUN
fnp-4682	371	11	.	.	PUNCT
fnp-4682	372	1	nature	nature	NOUN
fnp-4682	372	2	191	191	NUM
fnp-4682	372	3	,	,	PUNCT
fnp-4682	372	4	389	389	NUM
fnp-4682	372	5	-	-	SYM
fnp-4682	372	6	390	390	NUM
fnp-4682	372	7	.	.	PUNCT
fnp-4682	373	1	https://doi.org/10.1038/191389a0	https://doi.org/10.1038/191389a0	NUM
fnp-4682	373	2	erdmann	erdmann	PROPN
fnp-4682	373	3	,	,	PUNCT
fnp-4682	373	4	h.	h.	PROPN
fnp-4682	373	5	,	,	PUNCT
fnp-4682	373	6	scharf	scharf	PROPN
fnp-4682	373	7	,	,	PUNCT
fnp-4682	373	8	f.	f.	PROPN
fnp-4682	373	9	,	,	PUNCT
fnp-4682	373	10	gehling	gehle	VERB
fnp-4682	373	11	,	,	PUNCT
fnp-4682	373	12	s.	s.	PROPN
fnp-4682	373	13	,	,	PUNCT
fnp-4682	373	14	benet	benet	PROPN
fnp-4682	373	15	-	-	PUNCT
fnp-4682	373	16	pages	page	NOUN
fnp-4682	373	17	,	,	PUNCT
fnp-4682	373	18	a.	a.	NOUN
fnp-4682	373	19	,	,	PUNCT
fnp-4682	373	20	jakubiczka	jakubiczka	NOUN
fnp-4682	373	21	,	,	PUNCT
fnp-4682	373	22	s.	s.	PROPN
fnp-4682	373	23	,	,	PUNCT
fnp-4682	373	24	becker	becker	PROPN
fnp-4682	373	25	,	,	PUNCT
fnp-4682	373	26	k.	k.	PROPN
fnp-4682	373	27	,	,	PUNCT
fnp-4682	373	28	seipelt	seipelt	ADJ
fnp-4682	373	29	,	,	PUNCT
fnp-4682	373	30	m.	m.	NOUN
fnp-4682	373	31	,	,	PUNCT
fnp-4682	373	32	kleefeld	kleefeld	VERB
fnp-4682	373	33	,	,	PUNCT
fnp-4682	373	34	f.	f.	PROPN
fnp-4682	373	35	,	,	PUNCT
fnp-4682	373	36	knop	knop	PROPN
fnp-4682	373	37	,	,	PUNCT
fnp-4682	373	38	k.c	k.c	PROPN
fnp-4682	373	39	.	.	PROPN
fnp-4682	373	40	,	,	PUNCT
fnp-4682	373	41	prott	prott	PROPN
fnp-4682	373	42	,	,	PUNCT
fnp-4682	373	43	e.c	e.c	PROPN
fnp-4682	373	44	.	.	PROPN
fnp-4682	373	45	,	,	PUNCT
fnp-4682	373	46	et	et	PROPN
fnp-4682	373	47	al	al	PROPN
fnp-4682	373	48	.	.	PROPN
fnp-4682	373	49	(	(	PUNCT
fnp-4682	373	50	2022	2022	NUM
fnp-4682	373	51	)	)	PUNCT
fnp-4682	373	52	.	.	PUNCT
fnp-4682	374	1	methylation	methylation	NOUN
fnp-4682	374	2	of	of	ADP
fnp-4682	374	3	the	the	DET
fnp-4682	374	4	4q35	4q35	NUM
fnp-4682	374	5	d4z4	d4z4	NOUN
fnp-4682	374	6	repeat	repeat	NOUN
fnp-4682	374	7	defines	define	NOUN
fnp-4682	374	8	disease	disease	NOUN
fnp-4682	374	9	status	status	NOUN
fnp-4682	374	10	in	in	ADP
fnp-4682	374	11	facioscapulohumeral	facioscapulohumeral	ADJ
fnp-4682	374	12	muscular	muscular	ADJ
fnp-4682	374	13	dystrophy	dystrophy	NOUN
fnp-4682	374	14	.	.	PUNCT
fnp-4682	375	1	brain	brain	NOUN
fnp-4682	375	2	,	,	PUNCT
fnp-4682	375	3	epub	epub	NOUN
fnp-4682	375	4	ahead	ahead	ADV
fnp-4682	375	5	of	of	ADP
fnp-4682	375	6	print	print	NOUN
fnp-4682	375	7	.	.	PUNCT
fnp-4682	376	1	https://doi.org/10.1093/brain/awac336	https://doi.org/10.1093/brain/awac336	PROPN
fnp-4682	376	2	feldman	feldman	PROPN
fnp-4682	376	3	,	,	PUNCT
fnp-4682	376	4	h.c	h.c	PROPN
fnp-4682	376	5	.	.	PROPN
fnp-4682	376	6	,	,	PUNCT
fnp-4682	376	7	merlini	merlini	PROPN
fnp-4682	376	8	,	,	PUNCT
fnp-4682	376	9	e.	e.	PROPN
fnp-4682	376	10	,	,	PUNCT
fnp-4682	376	11	guijas	guijas	PROPN
fnp-4682	376	12	,	,	PUNCT
fnp-4682	376	13	c.	c.	PROPN
fnp-4682	376	14	,	,	PUNCT
fnp-4682	376	15	demeester	demeester	PROPN
fnp-4682	376	16	,	,	PUNCT
fnp-4682	376	17	k.e	k.e	PROPN
fnp-4682	376	18	.	.	PROPN
fnp-4682	376	19	,	,	PUNCT
fnp-4682	376	20	njomen	njomen	PROPN
fnp-4682	376	21	,	,	PUNCT
fnp-4682	376	22	e.	e.	PROPN
fnp-4682	376	23	,	,	PUNCT
fnp-4682	376	24	kozina	kozina	PROPN
fnp-4682	376	25	,	,	PUNCT
fnp-4682	376	26	e.m	e.m	PROPN
fnp-4682	376	27	.	.	PROPN
fnp-4682	376	28	,	,	PUNCT
fnp-4682	376	29	yokoyama	yokoyama	PROPN
fnp-4682	376	30	,	,	PUNCT
fnp-4682	376	31	m.	m.	NOUN
fnp-4682	376	32	,	,	PUNCT
fnp-4682	376	33	vinogradova	vinogradova	PROPN
fnp-4682	376	34	,	,	PUNCT
fnp-4682	376	35	e.	e.	PROPN
fnp-4682	376	36	,	,	PUNCT
fnp-4682	376	37	reardon	reardon	PROPN
fnp-4682	376	38	,	,	PUNCT
fnp-4682	376	39	h.t	h.t	PROPN
fnp-4682	376	40	.	.	PROPN
fnp-4682	376	41	,	,	PUNCT
fnp-4682	376	42	melillo	melillo	PROPN
fnp-4682	376	43	,	,	PUNCT
fnp-4682	376	44	b.	b.	PROPN
fnp-4682	376	45	,	,	PUNCT
fnp-4682	376	46	et	et	PROPN
fnp-4682	376	47	al	al	PROPN
fnp-4682	376	48	.	.	PROPN
fnp-4682	376	49	(	(	PUNCT
fnp-4682	376	50	2022	2022	NUM
fnp-4682	376	51	)	)	PUNCT
fnp-4682	376	52	.	.	PUNCT
fnp-4682	377	1	selective	selective	ADJ
fnp-4682	377	2	inhibitors	inhibitor	NOUN
fnp-4682	377	3	of	of	ADP
fnp-4682	377	4	sarm1	sarm1	NOUN
fnp-4682	377	5	targeting	target	VERB
fnp-4682	377	6	an	an	DET
fnp-4682	377	7	allosteric	allosteric	ADJ
fnp-4682	377	8	cysteine	cysteine	NOUN
fnp-4682	377	9	in	in	ADP
fnp-4682	377	10	the	the	DET
fnp-4682	377	11	autoregulatory	autoregulatory	ADJ
fnp-4682	377	12	arm	arm	NOUN
fnp-4682	377	13	domain	domain	NOUN
fnp-4682	377	14	.	.	PUNCT
fnp-4682	378	1	proc	proc	PROPN
fnp-4682	378	2	natl	natl	PROPN
fnp-4682	378	3	acad	acad	PROPN
fnp-4682	378	4	sci	sci	PROPN
fnp-4682	378	5	u	u	PROPN
fnp-4682	378	6	s	s	PROPN
fnp-4682	378	7	a	a	DET
fnp-4682	378	8	119	119	NUM
fnp-4682	378	9	,	,	PUNCT
fnp-4682	378	10	e2208457119	e2208457119	PROPN
fnp-4682	378	11	.	.	PUNCT
fnp-4682	378	12	https://doi.org/10.1073/pnas.2208457119	https://doi.org/10.1073/pnas.2208457119	PROPN
fnp-4682	378	13	figley	figley	NOUN
fnp-4682	378	14	,	,	PUNCT
fnp-4682	378	15	m.d	m.d	PROPN
fnp-4682	378	16	.	.	PROPN
fnp-4682	378	17	,	,	PUNCT
fnp-4682	378	18	gu	gu	PROPN
fnp-4682	378	19	,	,	PUNCT
fnp-4682	378	20	w.	w.	PROPN
fnp-4682	378	21	,	,	PUNCT
fnp-4682	378	22	nanson	nanson	NOUN
fnp-4682	378	23	,	,	PUNCT
fnp-4682	378	24	j.d	j.d	PROPN
fnp-4682	378	25	.	.	PROPN
fnp-4682	378	26	,	,	PUNCT
fnp-4682	378	27	shi	shi	PROPN
fnp-4682	378	28	,	,	PUNCT
fnp-4682	378	29	y.	y.	PROPN
fnp-4682	378	30	,	,	PUNCT
fnp-4682	378	31	sasaki	sasaki	PROPN
fnp-4682	378	32	,	,	PUNCT
fnp-4682	378	33	y.	y.	PROPN
fnp-4682	378	34	,	,	PUNCT
fnp-4682	378	35	cunnea	cunnea	PROPN
fnp-4682	378	36	,	,	PUNCT
fnp-4682	378	37	k.	k.	PROPN
fnp-4682	378	38	,	,	PUNCT
fnp-4682	378	39	malde	malde	PROPN
fnp-4682	378	40	,	,	PUNCT
fnp-4682	378	41	a.k	a.k	PROPN
fnp-4682	378	42	.	.	PROPN
fnp-4682	378	43	,	,	PUNCT
fnp-4682	378	44	jia	jia	PROPN
fnp-4682	378	45	,	,	PUNCT
fnp-4682	378	46	x.	x.	PROPN
fnp-4682	378	47	,	,	PUNCT
fnp-4682	378	48	luo	luo	PROPN
fnp-4682	378	49	,	,	PUNCT
fnp-4682	378	50	z.	z.	PROPN
fnp-4682	378	51	,	,	PUNCT
fnp-4682	378	52	saikot	saikot	NOUN
fnp-4682	378	53	,	,	PUNCT
fnp-4682	378	54	f.k	f.k	PROPN
fnp-4682	378	55	.	.	PROPN
fnp-4682	378	56	,	,	PUNCT
fnp-4682	378	57	et	et	PROPN
fnp-4682	378	58	al	al	PROPN
fnp-4682	378	59	.	.	PROPN
fnp-4682	378	60	(	(	PUNCT
fnp-4682	378	61	2021	2021	NUM
fnp-4682	378	62	)	)	PUNCT
fnp-4682	378	63	.	.	PUNCT
fnp-4682	379	1	sarm1	sarm1	PROPN
fnp-4682	379	2	is	be	AUX
fnp-4682	379	3	a	a	DET
fnp-4682	379	4	metabolic	metabolic	NOUN
fnp-4682	379	5	sensor	sensor	NOUN
fnp-4682	379	6	activated	activate	VERB
fnp-4682	379	7	by	by	ADP
fnp-4682	379	8	an	an	DET
fnp-4682	379	9	increased	increase	VERB
fnp-4682	379	10	nmn	nmn	PROPN
fnp-4682	379	11	/	/	SYM
fnp-4682	379	12	nad(+	nad(+	PROPN
fnp-4682	379	13	)	)	PUNCT
fnp-4682	379	14	ratio	ratio	NOUN
fnp-4682	379	15	to	to	AUX
fnp-4682	379	16	trigger	trigger	VERB
fnp-4682	379	17	axon	axon	NOUN
fnp-4682	379	18	degeneration	degeneration	NOUN
fnp-4682	379	19	.	.	PUNCT
fnp-4682	380	1	neuron	neuron	PROPN
fnp-4682	380	2	109	109	NUM
fnp-4682	380	3	,	,	PUNCT
fnp-4682	380	4	1118	1118	NUM
fnp-4682	380	5	-	-	SYM
fnp-4682	380	6	1136	1136	NUM
fnp-4682	380	7	.	.	PUNCT
fnp-4682	381	1	https://doi.org/10.1016/j.neuron.2021.02.009	https://doi.org/10.1016/j.neuron.2021.02.009	NUM
fnp-4682	381	2	gilley	gilley	NOUN
fnp-4682	381	3	,	,	PUNCT
fnp-4682	381	4	j.	j.	PROPN
fnp-4682	381	5	,	,	PUNCT
fnp-4682	381	6	jackson	jackson	PROPN
fnp-4682	381	7	,	,	PUNCT
fnp-4682	381	8	o.	o.	PROPN
fnp-4682	381	9	,	,	PUNCT
fnp-4682	381	10	pipis	pipis	ADJ
fnp-4682	381	11	,	,	PUNCT
fnp-4682	381	12	m.	m.	NOUN
fnp-4682	381	13	,	,	PUNCT
fnp-4682	381	14	estiar	estiar	NOUN
fnp-4682	381	15	,	,	PUNCT
fnp-4682	381	16	m.a	m.a	PROPN
fnp-4682	381	17	.	.	PROPN
fnp-4682	381	18	,	,	PUNCT
fnp-4682	381	19	al	al	PROPN
fnp-4682	381	20	-	-	PUNCT
fnp-4682	381	21	chalabi	chalabi	PROPN
fnp-4682	381	22	,	,	PUNCT
fnp-4682	381	23	a.	a.	NOUN
fnp-4682	381	24	,	,	PUNCT
fnp-4682	381	25	danzi	danzi	PROPN
fnp-4682	381	26	,	,	PUNCT
fnp-4682	381	27	m.c	m.c	PROPN
fnp-4682	381	28	.	.	PROPN
fnp-4682	381	29	,	,	PUNCT
fnp-4682	381	30	van	van	PROPN
fnp-4682	381	31	eijk	eijk	PROPN
fnp-4682	381	32	,	,	PUNCT
fnp-4682	381	33	k.r	k.r	PROPN
fnp-4682	381	34	.	.	PROPN
fnp-4682	381	35	,	,	PUNCT
fnp-4682	381	36	goutman	goutman	NOUN
fnp-4682	381	37	,	,	PUNCT
fnp-4682	381	38	s.a	s.a	PROPN
fnp-4682	381	39	.	.	PROPN
fnp-4682	381	40	,	,	PUNCT
fnp-4682	381	41	harms	harm	NOUN
fnp-4682	381	42	,	,	PUNCT
fnp-4682	381	43	m.b	m.b	PROPN
fnp-4682	381	44	.	.	PROPN
fnp-4682	381	45	,	,	PUNCT
fnp-4682	381	46	houlden	houlden	PROPN
fnp-4682	381	47	,	,	PUNCT
fnp-4682	381	48	h.	h.	PROPN
fnp-4682	381	49	,	,	PUNCT
fnp-4682	381	50	et	et	PROPN
fnp-4682	381	51	al	al	PROPN
fnp-4682	381	52	.	.	PROPN
fnp-4682	381	53	(	(	PUNCT
fnp-4682	381	54	2021	2021	NUM
fnp-4682	381	55	)	)	PUNCT
fnp-4682	381	56	.	.	PUNCT
fnp-4682	382	1	enrichment	enrichment	NOUN
fnp-4682	382	2	of	of	ADP
fnp-4682	382	3	sarm1	sarm1	PROPN
fnp-4682	382	4	alleles	allele	NOUN
fnp-4682	382	5	encoding	encode	VERB
fnp-4682	382	6	variants	variant	NOUN
fnp-4682	382	7	with	with	ADP
fnp-4682	382	8	constitutively	constitutively	ADV
fnp-4682	382	9	hyperactive	hyperactive	ADJ
fnp-4682	382	10	nadase	nadase	NOUN
fnp-4682	382	11	in	in	ADP
fnp-4682	382	12	patients	patient	NOUN
fnp-4682	382	13	with	with	ADP
fnp-4682	382	14	als	al	NOUN
fnp-4682	382	15	and	and	CCONJ
fnp-4682	382	16	other	other	ADJ
fnp-4682	382	17	motor	motor	NOUN
fnp-4682	382	18	nerve	nerve	NOUN
fnp-4682	382	19	disorders	disorder	NOUN
fnp-4682	382	20	.	.	PUNCT
fnp-4682	383	1	elife	elife	NOUN
fnp-4682	383	2	10	10	NUM
fnp-4682	383	3	,	,	PUNCT
fnp-4682	383	4	e70905	e70905	NOUN
fnp-4682	383	5	.	.	PUNCT
fnp-4682	384	1	https://doi.org/10.7554/elife.70905	https://doi.org/10.7554/elife.70905	PROPN
fnp-4682	384	2	goyal	goyal	PROPN
fnp-4682	384	3	,	,	PUNCT
fnp-4682	384	4	n.a	n.a	PROPN
fnp-4682	384	5	.	.	PROPN
fnp-4682	384	6	,	,	PUNCT
fnp-4682	384	7	coulis	coulis	PROPN
fnp-4682	384	8	,	,	PUNCT
fnp-4682	384	9	g.	g.	PROPN
fnp-4682	384	10	,	,	PUNCT
fnp-4682	384	11	duarte	duarte	PROPN
fnp-4682	384	12	,	,	PUNCT
fnp-4682	384	13	j.	j.	PROPN
fnp-4682	384	14	,	,	PUNCT
fnp-4682	384	15	farahat	farahat	PROPN
fnp-4682	384	16	,	,	PUNCT
fnp-4682	384	17	p.k	p.k	PROPN
fnp-4682	384	18	.	.	PROPN
fnp-4682	384	19	,	,	PUNCT
fnp-4682	384	20	mannaa	mannaa	PROPN
fnp-4682	384	21	,	,	PUNCT
fnp-4682	384	22	a.h	a.h	PROPN
fnp-4682	384	23	.	.	PROPN
fnp-4682	384	24	,	,	PUNCT
fnp-4682	384	25	cauchii	cauchii	PROPN
fnp-4682	384	26	,	,	PUNCT
fnp-4682	384	27	j.	j.	PROPN
fnp-4682	384	28	,	,	PUNCT
fnp-4682	384	29	irani	irani	PROPN
fnp-4682	384	30	,	,	PUNCT
fnp-4682	384	31	t.	t.	PROPN
fnp-4682	384	32	,	,	PUNCT
fnp-4682	384	33	araujo	araujo	NOUN
fnp-4682	384	34	,	,	PUNCT
fnp-4682	384	35	n.	n.	PROPN
fnp-4682	384	36	,	,	PUNCT
fnp-4682	384	37	wang	wang	PROPN
fnp-4682	384	38	,	,	PUNCT
fnp-4682	384	39	l.	l.	PROPN
fnp-4682	384	40	,	,	PUNCT
fnp-4682	384	41	wencel	wencel	PROPN
fnp-4682	384	42	,	,	PUNCT
fnp-4682	384	43	m.	m.	NOUN
fnp-4682	384	44	,	,	PUNCT
fnp-4682	384	45	et	et	PROPN
fnp-4682	384	46	al	al	PROPN
fnp-4682	384	47	.	.	PROPN
fnp-4682	384	48	(	(	PUNCT
fnp-4682	384	49	2022	2022	NUM
fnp-4682	384	50	)	)	PUNCT
fnp-4682	384	51	.	.	PUNCT
fnp-4682	385	1	immunophenotyping	immunophenotype	VERB
fnp-4682	385	2	of	of	ADP
fnp-4682	385	3	inclusion	inclusion	NOUN
fnp-4682	385	4	body	body	NOUN
fnp-4682	385	5	myositis	myositis	NOUN
fnp-4682	385	6	blood	blood	NOUN
fnp-4682	385	7	t	t	PROPN
fnp-4682	385	8	and	and	CCONJ
fnp-4682	385	9	nk	nk	PROPN
fnp-4682	385	10	cells	cell	NOUN
fnp-4682	385	11	.	.	PUNCT
fnp-4682	386	1	neurology	neurology	NOUN
fnp-4682	386	2	98	98	NUM
fnp-4682	386	3	,	,	PUNCT
fnp-4682	386	4	e1374	e1374	NOUN
fnp-4682	386	5	-	-	PUNCT
fnp-4682	386	6	e1383	e1383	NOUN
fnp-4682	386	7	.	.	PUNCT
fnp-4682	387	1	https://doi.org/10.1212/wnl.0000000000200013	https://doi.org/10.1212/wnl.0000000000200013	PROPN
fnp-4682	387	2	greenberg	greenberg	PROPN
fnp-4682	387	3	,	,	PUNCT
fnp-4682	387	4	s.a	s.a	PROPN
fnp-4682	387	5	.	.	PROPN
fnp-4682	387	6	,	,	PUNCT
fnp-4682	387	7	pinkus	pinku	NOUN
fnp-4682	387	8	,	,	PUNCT
fnp-4682	387	9	j.l	j.l	PROPN
fnp-4682	387	10	.	.	PROPN
fnp-4682	387	11	,	,	PUNCT
fnp-4682	387	12	kong	kong	PROPN
fnp-4682	387	13	,	,	PUNCT
fnp-4682	387	14	s.w	s.w	PROPN
fnp-4682	387	15	.	.	PROPN
fnp-4682	387	16	,	,	PUNCT
fnp-4682	387	17	baecher	baecher	PROPN
fnp-4682	387	18	-	-	PUNCT
fnp-4682	387	19	allan	allan	PROPN
fnp-4682	387	20	,	,	PUNCT
fnp-4682	387	21	c.	c.	PROPN
fnp-4682	387	22	,	,	PUNCT
fnp-4682	387	23	amato	amato	PROPN
fnp-4682	387	24	,	,	PUNCT
fnp-4682	387	25	a.a	a.a	PROPN
fnp-4682	387	26	.	.	PROPN
fnp-4682	387	27	,	,	PUNCT
fnp-4682	387	28	and	and	CCONJ
fnp-4682	387	29	dorfman	dorfman	PROPN
fnp-4682	387	30	,	,	PUNCT
fnp-4682	387	31	d.m	d.m	PROPN
fnp-4682	387	32	.	.	PUNCT
fnp-4682	387	33	(	(	PUNCT
fnp-4682	387	34	2019	2019	NUM
fnp-4682	387	35	)	)	PUNCT
fnp-4682	387	36	.	.	PUNCT
fnp-4682	388	1	highly	highly	ADV
fnp-4682	388	2	differentiated	differentiate	VERB
fnp-4682	388	3	cytotoxic	cytotoxic	ADJ
fnp-4682	388	4	t	t	NOUN
fnp-4682	388	5	cells	cell	NOUN
fnp-4682	388	6	in	in	ADP
fnp-4682	388	7	inclusion	inclusion	NOUN
fnp-4682	388	8	body	body	NOUN
fnp-4682	388	9	myositis	myositis	NOUN
fnp-4682	388	10	.	.	PUNCT
fnp-4682	389	1	brain	brain	PROPN
fnp-4682	389	2	142	142	NUM
fnp-4682	389	3	,	,	PUNCT
fnp-4682	389	4	2590	2590	NUM
fnp-4682	389	5	-	-	SYM
fnp-4682	389	6	2604	2604	NUM
fnp-4682	389	7	.	.	PUNCT
fnp-4682	390	1	https://doi.org/10.1093/brain/awz207	https://doi.org/10.1093/brain/awz207	VERB
fnp-4682	390	2	griffin	griffin	PROPN
fnp-4682	390	3	,	,	PUNCT
fnp-4682	390	4	j.w	j.w	PROPN
fnp-4682	390	5	.	.	PROPN
fnp-4682	390	6	,	,	PUNCT
fnp-4682	390	7	li	li	PROPN
fnp-4682	390	8	,	,	PUNCT
fnp-4682	390	9	c.y	c.y	PROPN
fnp-4682	390	10	.	.	PROPN
fnp-4682	390	11	,	,	PUNCT
fnp-4682	390	12	macko	macko	PROPN
fnp-4682	390	13	,	,	PUNCT
fnp-4682	390	14	c.	c.	PROPN
fnp-4682	390	15	,	,	PUNCT
fnp-4682	390	16	ho	ho	PROPN
fnp-4682	390	17	,	,	PUNCT
fnp-4682	390	18	t.w	t.w	PROPN
fnp-4682	390	19	.	.	PROPN
fnp-4682	390	20	,	,	PUNCT
fnp-4682	390	21	hsieh	hsieh	PROPN
fnp-4682	390	22	,	,	PUNCT
fnp-4682	390	23	s.t	s.t	PROPN
fnp-4682	390	24	.	.	PROPN
fnp-4682	390	25	,	,	PUNCT
fnp-4682	390	26	xue	xue	PROPN
fnp-4682	390	27	,	,	PUNCT
fnp-4682	390	28	p.	p.	PROPN
fnp-4682	390	29	,	,	PUNCT
fnp-4682	390	30	wang	wang	PROPN
fnp-4682	390	31	,	,	PUNCT
fnp-4682	390	32	f.a	f.a	PROPN
fnp-4682	390	33	.	.	PROPN
fnp-4682	390	34	,	,	PUNCT
fnp-4682	390	35	cornblath	cornblath	PROPN
fnp-4682	390	36	,	,	PUNCT
fnp-4682	390	37	d.r	d.r	PROPN
fnp-4682	390	38	.	.	PROPN
fnp-4682	390	39	,	,	PUNCT
fnp-4682	390	40	mckhann	mckhann	PROPN
fnp-4682	390	41	,	,	PUNCT
fnp-4682	390	42	g.m	g.m	PROPN
fnp-4682	390	43	.	.	PROPN
fnp-4682	390	44	,	,	PUNCT
fnp-4682	390	45	and	and	CCONJ
fnp-4682	390	46	asbury	asbury	PROPN
fnp-4682	390	47	,	,	PUNCT
fnp-4682	390	48	a.k	a.k	PROPN
fnp-4682	390	49	.	.	PROPN
fnp-4682	391	1	(	(	PUNCT
fnp-4682	391	2	1996	1996	NUM
fnp-4682	391	3	)	)	PUNCT
fnp-4682	391	4	.	.	PUNCT
fnp-4682	392	1	early	early	ADJ
fnp-4682	392	2	nodal	nodal	NOUN
fnp-4682	392	3	changes	change	NOUN
fnp-4682	392	4	in	in	ADP
fnp-4682	392	5	the	the	DET
fnp-4682	392	6	acute	acute	ADJ
fnp-4682	392	7	motor	motor	NOUN
fnp-4682	392	8	axonal	axonal	ADJ
fnp-4682	392	9	neuropathy	neuropathy	ADJ
fnp-4682	392	10	pattern	pattern	NOUN
fnp-4682	392	11	of	of	ADP
fnp-4682	392	12	the	the	DET
fnp-4682	392	13	guillain	guillain	NOUN
fnp-4682	392	14	-	-	PUNCT
fnp-4682	392	15	barre	barre	NOUN
fnp-4682	392	16	syndrome	syndrome	NOUN
fnp-4682	392	17	.	.	PUNCT
fnp-4682	393	1	j	j	PROPN
fnp-4682	393	2	neurocytol	neurocytol	NOUN
fnp-4682	393	3	25	25	NUM
fnp-4682	393	4	,	,	PUNCT
fnp-4682	393	5	33	33	NUM
fnp-4682	393	6	-	-	SYM
fnp-4682	393	7	51	51	NUM
fnp-4682	393	8	.	.	PUNCT
fnp-4682	394	1	https://doi.org/10.1007/bf02284784	https://doi.org/10.1007/bf02284784	NOUN
fnp-4682	394	2	hafer	hafer	NOUN
fnp-4682	394	3	-	-	PUNCT
fnp-4682	394	4	macko	macko	NOUN
fnp-4682	394	5	,	,	PUNCT
fnp-4682	394	6	c.	c.	PROPN
fnp-4682	394	7	,	,	PUNCT
fnp-4682	394	8	hsieh	hsieh	PROPN
fnp-4682	394	9	,	,	PUNCT
fnp-4682	394	10	s.t	s.t	PROPN
fnp-4682	394	11	.	.	PROPN
fnp-4682	394	12	,	,	PUNCT
fnp-4682	394	13	li	li	PROPN
fnp-4682	394	14	,	,	PUNCT
fnp-4682	394	15	c.y	c.y	PROPN
fnp-4682	394	16	.	.	PROPN
fnp-4682	394	17	,	,	PUNCT
fnp-4682	394	18	ho	ho	PROPN
fnp-4682	394	19	,	,	PUNCT
fnp-4682	394	20	t.w	t.w	PROPN
fnp-4682	394	21	.	.	PROPN
fnp-4682	394	22	,	,	PUNCT
fnp-4682	394	23	sheikh	sheikh	PROPN
fnp-4682	394	24	,	,	PUNCT
fnp-4682	394	25	k.	k.	PROPN
fnp-4682	394	26	,	,	PUNCT
fnp-4682	394	27	cornblath	cornblath	PROPN
fnp-4682	394	28	,	,	PUNCT
fnp-4682	394	29	d.r	d.r	PROPN
fnp-4682	394	30	.	.	PROPN
fnp-4682	394	31	,	,	PUNCT
fnp-4682	394	32	mckhann	mckhann	PROPN
fnp-4682	394	33	,	,	PUNCT
fnp-4682	394	34	g.m	g.m	PROPN
fnp-4682	394	35	.	.	PROPN
fnp-4682	394	36	,	,	PUNCT
fnp-4682	394	37	asbury	asbury	PROPN
fnp-4682	394	38	,	,	PUNCT
fnp-4682	394	39	a.k	a.k	PROPN
fnp-4682	394	40	.	.	PROPN
fnp-4682	394	41	,	,	PUNCT
fnp-4682	394	42	and	and	CCONJ
fnp-4682	394	43	griffin	griffin	PROPN
fnp-4682	394	44	,	,	PUNCT
fnp-4682	394	45	j.w	j.w	PROPN
fnp-4682	394	46	.	.	PROPN
fnp-4682	394	47	(	(	PUNCT
fnp-4682	394	48	1996a	1996a	NUM
fnp-4682	394	49	)	)	PUNCT
fnp-4682	394	50	.	.	PUNCT
fnp-4682	395	1	acute	acute	ADJ
fnp-4682	395	2	motor	motor	PROPN
fnp-4682	395	3	axonal	axonal	ADJ
fnp-4682	395	4	neuropathy	neuropathy	ADJ
fnp-4682	395	5	:	:	PUNCT
fnp-4682	395	6	an	an	DET
fnp-4682	395	7	antibody	antibody	NOUN
fnp-4682	395	8	-	-	PUNCT
fnp-4682	395	9	mediated	mediate	VERB
fnp-4682	395	10	attack	attack	NOUN
fnp-4682	395	11	on	on	ADP
fnp-4682	395	12	axolemma	axolemma	PROPN
fnp-4682	395	13	.	.	PUNCT
fnp-4682	396	1	ann	ann	PROPN
fnp-4682	396	2	neurol	neurol	PROPN
fnp-4682	396	3	40	40	NUM
fnp-4682	396	4	,	,	PUNCT
fnp-4682	396	5	635	635	NUM
fnp-4682	396	6	-	-	SYM
fnp-4682	396	7	644	644	NUM
fnp-4682	396	8	.	.	PUNCT
fnp-4682	397	1	https://doi.org/10.1002/ana.410400414	https://doi.org/10.1002/ana.410400414	PROPN
fnp-4682	397	2	hafer	hafer	NOUN
fnp-4682	397	3	-	-	PUNCT
fnp-4682	397	4	macko	macko	NOUN
fnp-4682	397	5	,	,	PUNCT
fnp-4682	397	6	c.e	c.e	PROPN
fnp-4682	397	7	.	.	PROPN
fnp-4682	397	8	,	,	PUNCT
fnp-4682	397	9	sheikh	sheikh	PROPN
fnp-4682	397	10	,	,	PUNCT
fnp-4682	397	11	k.a	k.a	PROPN
fnp-4682	397	12	.	.	PROPN
fnp-4682	397	13	,	,	PUNCT
fnp-4682	397	14	li	li	PROPN
fnp-4682	397	15	,	,	PUNCT
fnp-4682	397	16	c.y	c.y	PROPN
fnp-4682	397	17	.	.	PROPN
fnp-4682	397	18	,	,	PUNCT
fnp-4682	397	19	ho	ho	PROPN
fnp-4682	397	20	,	,	PUNCT
fnp-4682	397	21	t.w	t.w	PROPN
fnp-4682	397	22	.	.	PROPN
fnp-4682	397	23	,	,	PUNCT
fnp-4682	397	24	cornblath	cornblath	PROPN
fnp-4682	397	25	,	,	PUNCT
fnp-4682	397	26	d.r	d.r	PROPN
fnp-4682	397	27	.	.	PROPN
fnp-4682	397	28	,	,	PUNCT
fnp-4682	397	29	mckhann	mckhann	PROPN
fnp-4682	397	30	,	,	PUNCT
fnp-4682	397	31	g.m	g.m	PROPN
fnp-4682	397	32	.	.	PROPN
fnp-4682	397	33	,	,	PUNCT
fnp-4682	397	34	asbury	asbury	PROPN
fnp-4682	397	35	,	,	PUNCT
fnp-4682	397	36	a.k	a.k	PROPN
fnp-4682	397	37	.	.	PROPN
fnp-4682	397	38	,	,	PUNCT
fnp-4682	397	39	and	and	CCONJ
fnp-4682	397	40	griffin	griffin	PROPN
fnp-4682	397	41	,	,	PUNCT
fnp-4682	397	42	j.w	j.w	PROPN
fnp-4682	397	43	.	.	PROPN
fnp-4682	397	44	(	(	PUNCT
fnp-4682	397	45	1996b	1996b	NUM
fnp-4682	397	46	)	)	PUNCT
fnp-4682	397	47	.	.	PUNCT
fnp-4682	398	1	immune	immune	ADJ
fnp-4682	398	2	attack	attack	NOUN
fnp-4682	398	3	on	on	ADP
fnp-4682	398	4	the	the	DET
fnp-4682	398	5	schwann	schwann	PROPN
fnp-4682	398	6	cell	cell	NOUN
fnp-4682	398	7	surface	surface	NOUN
fnp-4682	398	8	in	in	ADP
fnp-4682	398	9	acute	acute	ADJ
fnp-4682	398	10	inflammatory	inflammatory	ADJ
fnp-4682	398	11	demyelinating	demyelinate	VERB
fnp-4682	398	12	polyneuropathy	polyneuropathy	NOUN
fnp-4682	398	13	.	.	PUNCT
fnp-4682	399	1	ann	ann	PROPN
fnp-4682	399	2	neurol	neurol	PROPN
fnp-4682	399	3	39	39	NUM
fnp-4682	399	4	,	,	PUNCT
fnp-4682	399	5	625	625	NUM
fnp-4682	399	6	-	-	SYM
fnp-4682	399	7	635	635	NUM
fnp-4682	399	8	.	.	PUNCT
fnp-4682	400	1	https://doi.org/10.1002/ana.410390512	https://doi.org/10.1002/ana.410390512	PROPN
fnp-4682	400	2	hedberg	hedberg	PROPN
fnp-4682	400	3	-	-	PUNCT
fnp-4682	400	4	oldfors	oldfor	NOUN
fnp-4682	400	5	,	,	PUNCT
fnp-4682	400	6	c.	c.	PROPN
fnp-4682	400	7	,	,	PUNCT
fnp-4682	400	8	lindgren	lindgren	PROPN
fnp-4682	400	9	,	,	PUNCT
fnp-4682	400	10	u.	u.	PROPN
fnp-4682	400	11	,	,	PUNCT
fnp-4682	400	12	visuttijai	visuttijai	PROPN
fnp-4682	400	13	,	,	PUNCT
fnp-4682	400	14	k.	k.	PROPN
fnp-4682	400	15	,	,	PUNCT
fnp-4682	400	16	loof	loof	PROPN
fnp-4682	400	17	,	,	PUNCT
fnp-4682	400	18	d.	d.	PROPN
fnp-4682	400	19	,	,	PUNCT
fnp-4682	400	20	roos	roos	PROPN
fnp-4682	400	21	,	,	PUNCT
fnp-4682	400	22	s.	s.	PROPN
fnp-4682	400	23	,	,	PUNCT
fnp-4682	400	24	thomsen	thomsen	PROPN
fnp-4682	400	25	,	,	PUNCT
fnp-4682	400	26	c.	c.	PROPN
fnp-4682	400	27	,	,	PUNCT
fnp-4682	400	28	and	and	CCONJ
fnp-4682	400	29	oldfors	oldfor	NOUN
fnp-4682	400	30	,	,	PUNCT
fnp-4682	400	31	a.	a.	NOUN
fnp-4682	400	32	(	(	PUNCT
fnp-4682	400	33	2022	2022	NUM
fnp-4682	400	34	)	)	PUNCT
fnp-4682	400	35	.	.	PUNCT
fnp-4682	401	1	respiratory	respiratory	ADJ
fnp-4682	401	2	chain	chain	NOUN
fnp-4682	401	3	dysfunction	dysfunction	NOUN
fnp-4682	401	4	in	in	ADP
fnp-4682	401	5	perifascicular	perifascicular	ADJ
fnp-4682	401	6	muscle	muscle	NOUN
fnp-4682	401	7	fibres	fibre	NOUN
fnp-4682	401	8	in	in	ADP
fnp-4682	401	9	patients	patient	NOUN
fnp-4682	401	10	with	with	ADP
fnp-4682	401	11	dermatomyositis	dermatomyositis	PROPN
fnp-4682	401	12	is	be	AUX
fnp-4682	401	13	associated	associate	VERB
fnp-4682	401	14	with	with	ADP
fnp-4682	401	15	mitochondrial	mitochondrial	ADJ
fnp-4682	401	16	dna	dna	NOUN
fnp-4682	401	17	depletion	depletion	NOUN
fnp-4682	401	18	.	.	PUNCT
fnp-4682	402	1	neuropathol	neuropathol	PROPN
fnp-4682	402	2	appl	appl	PROPN
fnp-4682	402	3	neurobiol	neurobiol	PROPN
fnp-4682	402	4	48	48	NUM
fnp-4682	402	5	,	,	PUNCT
fnp-4682	402	6	e12841	e12841	PROPN
fnp-4682	402	7	.	.	PUNCT
fnp-4682	403	1	https://doi.org/10.1111/nan.12841	https://doi.org/10.1111/nan.12841	ADV
fnp-4682	403	2	hejbøl	hejbøl	ADJ
fnp-4682	403	3	,	,	PUNCT
fnp-4682	403	4	e.k	e.k	PROPN
fnp-4682	403	5	.	.	PROPN
fnp-4682	403	6	,	,	PUNCT
fnp-4682	403	7	harbo	harbo	NOUN
fnp-4682	403	8	,	,	PUNCT
fnp-4682	403	9	t.	t.	PROPN
fnp-4682	403	10	,	,	PUNCT
fnp-4682	403	11	agergaard	agergaard	PROPN
fnp-4682	403	12	,	,	PUNCT
fnp-4682	403	13	j.	j.	PROPN
fnp-4682	403	14	,	,	PUNCT
fnp-4682	403	15	madsen	madsen	PROPN
fnp-4682	403	16	,	,	PUNCT
fnp-4682	403	17	l.b	l.b	PROPN
fnp-4682	403	18	.	.	PROPN
fnp-4682	403	19	,	,	PUNCT
fnp-4682	403	20	pedersen	pedersen	PROPN
fnp-4682	403	21	,	,	PUNCT
fnp-4682	403	22	t.h	t.h	PROPN
fnp-4682	403	23	.	.	PROPN
fnp-4682	403	24	,	,	PUNCT
fnp-4682	403	25	ostergaard	ostergaard	ADV
fnp-4682	403	26	,	,	PUNCT
fnp-4682	403	27	l.j	l.j	PROPN
fnp-4682	403	28	.	.	PROPN
fnp-4682	403	29	,	,	PUNCT
fnp-4682	403	30	andersen	andersen	PROPN
fnp-4682	403	31	,	,	PUNCT
fnp-4682	403	32	h.	h.	PROPN
fnp-4682	403	33	,	,	PUNCT
fnp-4682	403	34	schroder	schroder	PROPN
fnp-4682	403	35	,	,	PUNCT
fnp-4682	403	36	h.d	h.d	PROPN
fnp-4682	403	37	.	.	PROPN
fnp-4682	403	38	,	,	PUNCT
fnp-4682	403	39	and	and	CCONJ
fnp-4682	403	40	tankisi	tankisi	ADJ
fnp-4682	403	41	,	,	PUNCT
fnp-4682	403	42	h.	h.	PROPN
fnp-4682	403	43	(	(	PUNCT
fnp-4682	403	44	2022	2022	NUM
fnp-4682	403	45	)	)	PUNCT
fnp-4682	403	46	.	.	PUNCT
fnp-4682	404	1	myopathy	myopathy	ADJ
fnp-4682	404	2	as	as	ADP
fnp-4682	404	3	a	a	DET
fnp-4682	404	4	cause	cause	NOUN
fnp-4682	404	5	of	of	ADP
fnp-4682	404	6	fatigue	fatigue	NOUN
fnp-4682	404	7	in	in	ADP
fnp-4682	404	8	long	long	ADJ
fnp-4682	404	9	-	-	PUNCT
fnp-4682	404	10	term	term	NOUN
fnp-4682	404	11	post	post	ADJ
fnp-4682	404	12	-	-	ADJ
fnp-4682	404	13	covid-19	covid-19	ADJ
fnp-4682	404	14	symptoms	symptom	NOUN
fnp-4682	404	15	:	:	PUNCT
fnp-4682	404	16	evidence	evidence	NOUN
fnp-4682	404	17	of	of	ADP
fnp-4682	404	18	skeletal	skeletal	ADJ
fnp-4682	404	19	muscle	muscle	NOUN
fnp-4682	404	20	histopathology	histopathology	NOUN
fnp-4682	404	21	.	.	PUNCT
fnp-4682	405	1	eur	eur	PROPN
fnp-4682	405	2	j	j	PROPN
fnp-4682	405	3	neurol	neurol	PROPN
fnp-4682	405	4	29	29	NUM
fnp-4682	405	5	,	,	PUNCT
fnp-4682	405	6	2832	2832	NUM
fnp-4682	405	7	-	-	SYM
fnp-4682	405	8	2841	2841	NUM
fnp-4682	405	9	.	.	PUNCT
fnp-4682	406	1	https://doi.org/10.1111/ene.15435	https://doi.org/10.1111/ene.15435	PROPN
fnp-4682	406	2	hiniker	hiniker	PROPN
fnp-4682	406	3	,	,	PUNCT
fnp-4682	406	4	a.	a.	PROPN
fnp-4682	406	5	,	,	PUNCT
fnp-4682	406	6	daniels	daniels	PROPN
fnp-4682	406	7	,	,	PUNCT
fnp-4682	406	8	b.h	b.h	PROPN
fnp-4682	406	9	.	.	PROPN
fnp-4682	406	10	,	,	PUNCT
fnp-4682	406	11	lee	lee	PROPN
fnp-4682	406	12	,	,	PUNCT
fnp-4682	406	13	h.s	h.s	PROPN
fnp-4682	406	14	.	.	PROPN
fnp-4682	406	15	,	,	PUNCT
fnp-4682	406	16	and	and	CCONJ
fnp-4682	406	17	margeta	margeta	NOUN
fnp-4682	406	18	,	,	PUNCT
fnp-4682	406	19	m.	m.	NOUN
fnp-4682	406	20	(	(	PUNCT
fnp-4682	406	21	2013	2013	NUM
fnp-4682	406	22	)	)	PUNCT
fnp-4682	406	23	.	.	PUNCT
fnp-4682	407	1	comparative	comparative	ADJ
fnp-4682	407	2	utility	utility	NOUN
fnp-4682	407	3	of	of	ADP
fnp-4682	407	4	lc3	lc3	NOUN
fnp-4682	407	5	,	,	PUNCT
fnp-4682	407	6	p62	p62	NOUN
fnp-4682	407	7	and	and	CCONJ
fnp-4682	407	8	tdp-43	tdp-43	NOUN
fnp-4682	407	9	immunohistochemistry	immunohistochemistry	NOUN
fnp-4682	407	10	in	in	ADP
fnp-4682	407	11	differentiation	differentiation	NOUN
fnp-4682	407	12	of	of	ADP
fnp-4682	407	13	inclusion	inclusion	NOUN
fnp-4682	407	14	body	body	NOUN
fnp-4682	407	15	myositis	myositis	PROPN
fnp-4682	407	16	from	from	ADP
fnp-4682	407	17	polymyositis	polymyositis	PROPN
fnp-4682	407	18	and	and	CCONJ
fnp-4682	407	19	related	relate	VERB
fnp-4682	407	20	inflammatory	inflammatory	ADJ
fnp-4682	407	21	myopathies	myopathy	NOUN
fnp-4682	407	22	.	.	PUNCT
fnp-4682	408	1	acta	acta	PROPN
fnp-4682	408	2	neuropathol	neuropathol	PROPN
fnp-4682	408	3	commun	commun	PROPN
fnp-4682	408	4	1	1	NUM
fnp-4682	408	5	,	,	PUNCT
fnp-4682	408	6	29	29	NUM
fnp-4682	408	7	.	.	PUNCT
fnp-4682	409	1	https://doi.org/10.1186/2051-5960-1-29	https://doi.org/10.1186/2051-5960-1-29	VERB
fnp-4682	409	2	hughes	hughes	PROPN
fnp-4682	409	3	,	,	PUNCT
fnp-4682	409	4	r.o	r.o	PROPN
fnp-4682	409	5	.	.	PROPN
fnp-4682	409	6	,	,	PUNCT
fnp-4682	409	7	bosanac	bosanac	NOUN
fnp-4682	409	8	,	,	PUNCT
fnp-4682	409	9	t.	t.	PROPN
fnp-4682	409	10	,	,	PUNCT
fnp-4682	409	11	mao	mao	PROPN
fnp-4682	409	12	,	,	PUNCT
fnp-4682	409	13	x.	x.	PROPN
fnp-4682	409	14	,	,	PUNCT
fnp-4682	409	15	engber	engber	PROPN
fnp-4682	409	16	,	,	PUNCT
fnp-4682	409	17	t.m	t.m	PROPN
fnp-4682	409	18	.	.	PROPN
fnp-4682	409	19	,	,	PUNCT
fnp-4682	409	20	diantonio	diantonio	PROPN
fnp-4682	409	21	,	,	PUNCT
fnp-4682	409	22	a.	a.	NOUN
fnp-4682	409	23	,	,	PUNCT
fnp-4682	409	24	milbrandt	milbrandt	PROPN
fnp-4682	409	25	,	,	PUNCT
fnp-4682	409	26	j.	j.	PROPN
fnp-4682	409	27	,	,	PUNCT
fnp-4682	409	28	devraj	devraj	PROPN
fnp-4682	409	29	,	,	PUNCT
fnp-4682	409	30	r.	r.	PROPN
fnp-4682	409	31	,	,	PUNCT
fnp-4682	409	32	and	and	CCONJ
fnp-4682	409	33	krauss	krauss	PROPN
fnp-4682	409	34	,	,	PUNCT
fnp-4682	409	35	r.	r.	PROPN
fnp-4682	409	36	(	(	PUNCT
fnp-4682	409	37	2021	2021	NUM
fnp-4682	409	38	)	)	PUNCT
fnp-4682	409	39	.	.	PUNCT
fnp-4682	410	1	small	small	ADJ
fnp-4682	410	2	molecule	molecule	NOUN
fnp-4682	410	3	sarm1	sarm1	PUNCT
fnp-4682	411	1	inhibitors	inhibitor	NOUN
fnp-4682	411	2	recapitulate	recapitulate	VERB
fnp-4682	411	3	the	the	DET
fnp-4682	411	4	sarm1(-/-	sarm1(-/-	PROPN
fnp-4682	411	5	)	)	PUNCT
fnp-4682	411	6	phenotype	phenotype	NOUN
fnp-4682	411	7	and	and	CCONJ
fnp-4682	411	8	allow	allow	VERB
fnp-4682	411	9	recovery	recovery	NOUN
fnp-4682	411	10	of	of	ADP
fnp-4682	411	11	a	a	DET
fnp-4682	411	12	metastable	metastable	ADJ
fnp-4682	411	13	pool	pool	NOUN
fnp-4682	411	14	of	of	ADP
fnp-4682	411	15	axons	axon	NOUN
fnp-4682	411	16	fated	fate	VERB
fnp-4682	411	17	to	to	PART
fnp-4682	411	18	degenerate	degenerate	VERB
fnp-4682	411	19	.	.	PUNCT
fnp-4682	412	1	cell	cell	NOUN
fnp-4682	412	2	rep	rep	PROPN
fnp-4682	412	3	34	34	NUM
fnp-4682	412	4	,	,	PUNCT
fnp-4682	412	5	108588	108588	NUM
fnp-4682	412	6	.	.	PUNCT
fnp-4682	413	1	https://doi.org/10.1016/j.celrep.2020.108588	https://doi.org/10.1016/j.celrep.2020.108588	PROPN
fnp-4682	413	2	huppke	huppke	PROPN
fnp-4682	413	3	,	,	PUNCT
fnp-4682	413	4	p.	p.	PROPN
fnp-4682	413	5	,	,	PUNCT
fnp-4682	413	6	wegener	wegener	PROPN
fnp-4682	413	7	,	,	PUNCT
fnp-4682	413	8	e.	e.	PROPN
fnp-4682	413	9	,	,	PUNCT
fnp-4682	413	10	gilley	gilley	PROPN
fnp-4682	413	11	,	,	PUNCT
fnp-4682	413	12	j.	j.	PROPN
fnp-4682	413	13	,	,	PUNCT
fnp-4682	413	14	angeletti	angeletti	PROPN
fnp-4682	413	15	,	,	PUNCT
fnp-4682	413	16	c.	c.	NOUN
fnp-4682	413	17	,	,	PUNCT
fnp-4682	413	18	kurth	kurth	PROPN
fnp-4682	413	19	,	,	PUNCT
fnp-4682	413	20	i.	i.	NOUN
fnp-4682	413	21	,	,	PUNCT
fnp-4682	413	22	drenth	drenth	PROPN
fnp-4682	413	23	,	,	PUNCT
fnp-4682	413	24	j.p.h	j.p.h	PROPN
fnp-4682	413	25	.	.	PROPN
fnp-4682	413	26	,	,	PUNCT
fnp-4682	413	27	stadelmann	stadelmann	PROPN
fnp-4682	413	28	,	,	PUNCT
fnp-4682	413	29	c.	c.	NOUN
fnp-4682	413	30	,	,	PUNCT
fnp-4682	413	31	barrantes	barrante	NOUN
fnp-4682	413	32	-	-	PUNCT
fnp-4682	413	33	freer	free	ADJ
fnp-4682	413	34	,	,	PUNCT
fnp-4682	413	35	a.	a.	NOUN
fnp-4682	413	36	,	,	PUNCT
fnp-4682	413	37	bruck	bruck	NOUN
fnp-4682	413	38	,	,	PUNCT
fnp-4682	413	39	w.	w.	PROPN
fnp-4682	413	40	,	,	PUNCT
fnp-4682	413	41	thiele	thiele	PROPN
fnp-4682	413	42	,	,	PUNCT
fnp-4682	413	43	h.	h.	PROPN
fnp-4682	413	44	,	,	PUNCT
fnp-4682	413	45	et	et	PROPN
fnp-4682	413	46	al	al	PROPN
fnp-4682	413	47	.	.	PROPN
fnp-4682	413	48	(	(	PUNCT
fnp-4682	413	49	2019	2019	NUM
fnp-4682	413	50	)	)	PUNCT
fnp-4682	413	51	.	.	PUNCT
fnp-4682	414	1	homozygous	homozygous	ADJ
fnp-4682	414	2	nmnat2	nmnat2	NOUN
fnp-4682	414	3	mutation	mutation	NOUN
fnp-4682	414	4	in	in	ADP
fnp-4682	414	5	sisters	sister	NOUN
fnp-4682	414	6	with	with	ADP
fnp-4682	414	7	polyneuropathy	polyneuropathy	ADJ
fnp-4682	414	8	and	and	CCONJ
fnp-4682	414	9	erythromelalgia	erythromelalgia	NOUN
fnp-4682	414	10	.	.	PUNCT
fnp-4682	415	1	exp	exp	NOUN
fnp-4682	415	2	neurol	neurol	NOUN
fnp-4682	415	3	320	320	NUM
fnp-4682	415	4	,	,	PUNCT
fnp-4682	415	5	112958	112958	NUM
fnp-4682	415	6	.	.	PUNCT
fnp-4682	416	1	https://doi.org/10.1016/j.expneurol.2019.112958	https://doi.org/10.1016/j.expneurol.2019.112958	PROPN
fnp-4682	416	2	inoue	inoue	PROPN
fnp-4682	416	3	,	,	PUNCT
fnp-4682	416	4	m.	m.	NOUN
fnp-4682	416	5	,	,	PUNCT
fnp-4682	416	6	noguchi	noguchi	PROPN
fnp-4682	416	7	,	,	PUNCT
fnp-4682	416	8	s.	s.	PROPN
fnp-4682	416	9	,	,	PUNCT
fnp-4682	416	10	inoue	inoue	PROPN
fnp-4682	416	11	,	,	PUNCT
fnp-4682	416	12	y.u	y.u	PROPN
fnp-4682	416	13	.	.	PROPN
fnp-4682	416	14	,	,	PUNCT
fnp-4682	416	15	iida	iida	PROPN
fnp-4682	416	16	,	,	PUNCT
fnp-4682	416	17	a.	a.	PROPN
fnp-4682	416	18	,	,	PUNCT
fnp-4682	416	19	ogawa	ogawa	PROPN
fnp-4682	416	20	,	,	PUNCT
fnp-4682	416	21	m.	m.	NOUN
fnp-4682	416	22	,	,	PUNCT
fnp-4682	416	23	bengoechea	bengoechea	PROPN
fnp-4682	416	24	,	,	PUNCT
fnp-4682	416	25	r.	r.	PROPN
fnp-4682	416	26	,	,	PUNCT
fnp-4682	416	27	pittman	pittman	NOUN
fnp-4682	416	28	,	,	PUNCT
fnp-4682	416	29	s.k	s.k	PROPN
fnp-4682	416	30	.	.	PROPN
fnp-4682	416	31	,	,	PUNCT
fnp-4682	416	32	hayashi	hayashi	PROPN
fnp-4682	416	33	,	,	PUNCT
fnp-4682	416	34	s.	s.	PROPN
fnp-4682	416	35	,	,	PUNCT
fnp-4682	416	36	watanabe	watanabe	PROPN
fnp-4682	416	37	,	,	PUNCT
fnp-4682	416	38	k.	k.	PROPN
fnp-4682	416	39	,	,	PUNCT
fnp-4682	416	40	hosoi	hosoi	PROPN
fnp-4682	416	41	,	,	PUNCT
fnp-4682	416	42	y.	y.	PROPN
fnp-4682	416	43	,	,	PUNCT
fnp-4682	416	44	et	et	PROPN
fnp-4682	416	45	al	al	PROPN
fnp-4682	416	46	.	.	PROPN
fnp-4682	416	47	(	(	PUNCT
fnp-4682	416	48	2023	2023	NUM
fnp-4682	416	49	)	)	PUNCT
fnp-4682	416	50	.	.	PUNCT
fnp-4682	417	1	distinctive	distinctive	ADJ
fnp-4682	417	2	chaperonopathy	chaperonopathy	NOUN
fnp-4682	417	3	in	in	ADP
fnp-4682	417	4	skeletal	skeletal	ADJ
fnp-4682	417	5	muscle	muscle	NOUN
fnp-4682	417	6	associated	associate	VERB
fnp-4682	417	7	with	with	ADP
fnp-4682	417	8	the	the	DET
fnp-4682	417	9	dominant	dominant	ADJ
fnp-4682	417	10	variant	variant	NOUN
fnp-4682	417	11	in	in	ADP
fnp-4682	417	12	dnajb4	dnajb4	PROPN
fnp-4682	417	13	.	.	PUNCT
fnp-4682	418	1	acta	acta	PROPN
fnp-4682	418	2	neuropathol	neuropathol	PROPN
fnp-4682	418	3	145	145	NUM
fnp-4682	418	4	,	,	PUNCT
fnp-4682	418	5	235	235	NUM
fnp-4682	418	6	-	-	SYM
fnp-4682	418	7	255	255	NUM
fnp-4682	418	8	.	.	PUNCT
fnp-4682	419	1	https://doi.org/10.1007/s00401-022-02530-4	https://doi.org/10.1007/s00401-022-02530-4	NUM
fnp-4682	419	2	kleefeld	kleefeld	NOUN
fnp-4682	419	3	,	,	PUNCT
fnp-4682	419	4	f.	f.	PROPN
fnp-4682	419	5	,	,	PUNCT
fnp-4682	419	6	uruha	uruha	ADJ
fnp-4682	419	7	,	,	PUNCT
fnp-4682	419	8	a.	a.	NOUN
fnp-4682	419	9	,	,	PUNCT
fnp-4682	419	10	schanzer	schanzer	NOUN
fnp-4682	419	11	,	,	PUNCT
fnp-4682	419	12	a.	a.	NOUN
fnp-4682	419	13	,	,	PUNCT
fnp-4682	419	14	nishimura	nishimura	PROPN
fnp-4682	419	15	,	,	PUNCT
fnp-4682	419	16	a.	a.	PROPN
fnp-4682	419	17	,	,	PUNCT
fnp-4682	419	18	roos	roo	NOUN
fnp-4682	419	19	,	,	PUNCT
fnp-4682	419	20	a.	a.	NOUN
fnp-4682	419	21	,	,	PUNCT
fnp-4682	419	22	schneider	schneider	PROPN
fnp-4682	419	23	,	,	PUNCT
fnp-4682	419	24	u.	u.	PROPN
fnp-4682	419	25	,	,	PUNCT
fnp-4682	419	26	goebel	goebel	NOUN
fnp-4682	419	27	,	,	PUNCT
fnp-4682	419	28	h.h	h.h	PROPN
fnp-4682	419	29	.	.	PROPN
fnp-4682	419	30	,	,	PUNCT
fnp-4682	419	31	schuelke	schuelke	PROPN
fnp-4682	419	32	,	,	PUNCT
fnp-4682	419	33	m.	m.	NOUN
fnp-4682	419	34	,	,	PUNCT
fnp-4682	419	35	hahn	hahn	PROPN
fnp-4682	419	36	,	,	PUNCT
fnp-4682	419	37	k.	k.	PROPN
fnp-4682	419	38	,	,	PUNCT
fnp-4682	419	39	preusse	preusse	PROPN
fnp-4682	419	40	,	,	PUNCT
fnp-4682	419	41	c.	c.	PROPN
fnp-4682	419	42	,	,	PUNCT
fnp-4682	419	43	et	et	PROPN
fnp-4682	419	44	al	al	PROPN
fnp-4682	419	45	.	.	PROPN
fnp-4682	419	46	(	(	PUNCT
fnp-4682	419	47	2022	2022	NUM
fnp-4682	419	48	)	)	PUNCT
fnp-4682	419	49	.	.	PUNCT
fnp-4682	420	1	morphologic	morphologic	ADJ
fnp-4682	420	2	and	and	CCONJ
fnp-4682	420	3	molecular	molecular	ADJ
fnp-4682	420	4	patterns	pattern	NOUN
fnp-4682	420	5	of	of	ADP
fnp-4682	420	6	polymyositis	polymyositis	PROPN
fnp-4682	420	7	with	with	ADP
fnp-4682	420	8	mitochondrial	mitochondrial	ADJ
fnp-4682	420	9	pathology	pathology	NOUN
fnp-4682	420	10	and	and	CCONJ
fnp-4682	420	11	inclusion	inclusion	NOUN
fnp-4682	420	12	body	body	NOUN
fnp-4682	420	13	myositis	myositis	PROPN
fnp-4682	420	14	.	.	PUNCT
fnp-4682	421	1	neurology	neurology	NOUN
fnp-4682	421	2	99	99	NUM
fnp-4682	421	3	,	,	PUNCT
fnp-4682	421	4	e2212	e2212	NOUN
fnp-4682	421	5	-	-	PUNCT
fnp-4682	421	6	e2222	e2222	NOUN
fnp-4682	421	7	.	.	PUNCT
fnp-4682	422	1	https://doi.org/10.1212/wnl.0000000000201103	https://doi.org/10.1212/wnl.0000000000201103	ADJ
fnp-4682	422	2	knauss	knauss	ADJ
fnp-4682	422	3	,	,	PUNCT
fnp-4682	422	4	s.	s.	PROPN
fnp-4682	422	5	,	,	PUNCT
fnp-4682	422	6	preusse	preusse	NOUN
fnp-4682	422	7	,	,	PUNCT
fnp-4682	422	8	c.	c.	PROPN
fnp-4682	422	9	,	,	PUNCT
fnp-4682	422	10	allenbach	allenbach	ADV
fnp-4682	422	11	,	,	PUNCT
fnp-4682	422	12	y.	y.	PROPN
fnp-4682	422	13	,	,	PUNCT
fnp-4682	422	14	leonard	leonard	PROPN
fnp-4682	422	15	-	-	PUNCT
fnp-4682	422	16	louis	louis	PROPN
fnp-4682	422	17	,	,	PUNCT
fnp-4682	422	18	s.	s.	PROPN
fnp-4682	422	19	,	,	PUNCT
fnp-4682	422	20	touat	touat	PROPN
fnp-4682	422	21	,	,	PUNCT
fnp-4682	422	22	m.	m.	NOUN
fnp-4682	422	23	,	,	PUNCT
fnp-4682	422	24	fischer	fischer	PROPN
fnp-4682	422	25	,	,	PUNCT
fnp-4682	422	26	n.	n.	NOUN
fnp-4682	422	27	,	,	PUNCT
fnp-4682	422	28	radbruch	radbruch	PROPN
fnp-4682	422	29	,	,	PUNCT
fnp-4682	422	30	h.	h.	PROPN
fnp-4682	422	31	,	,	PUNCT
fnp-4682	422	32	mothes	mothe	VERB
fnp-4682	422	33	,	,	PUNCT
fnp-4682	422	34	r.	r.	PROPN
fnp-4682	422	35	,	,	PUNCT
fnp-4682	422	36	matyash	matyash	NOUN
fnp-4682	422	37	,	,	PUNCT
fnp-4682	422	38	v.	v.	ADP
fnp-4682	422	39	,	,	PUNCT
fnp-4682	422	40	bohmerle	bohmerle	PROPN
fnp-4682	422	41	,	,	PUNCT
fnp-4682	422	42	w.	w.	PROPN
fnp-4682	422	43	,	,	PUNCT
fnp-4682	422	44	et	et	PROPN
fnp-4682	422	45	al	al	PROPN
fnp-4682	422	46	.	.	PROPN
fnp-4682	423	1	(	(	PUNCT
fnp-4682	423	2	2019	2019	NUM
fnp-4682	423	3	)	)	PUNCT
fnp-4682	423	4	.	.	PUNCT
fnp-4682	424	1	pd1	pd1	VERB
fnp-4682	424	2	pathway	pathway	NOUN
fnp-4682	424	3	in	in	ADP
fnp-4682	424	4	immune	immune	NOUN
fnp-4682	424	5	-	-	PUNCT
fnp-4682	424	6	mediated	mediate	VERB
fnp-4682	424	7	myopathies	myopathy	NOUN
fnp-4682	424	8	:	:	PUNCT
fnp-4682	424	9	pathogenesis	pathogenesis	NOUN
fnp-4682	424	10	of	of	ADP
fnp-4682	424	11	dysfunctional	dysfunctional	ADJ
fnp-4682	424	12	t	t	PROPN
fnp-4682	424	13	cells	cell	NOUN
fnp-4682	424	14	revisited	revisit	VERB
fnp-4682	424	15	.	.	PUNCT
fnp-4682	425	1	neurol	neurol	PROPN
fnp-4682	425	2	neuroimmunol	neuroimmunol	PROPN
fnp-4682	425	3	neuroinflamm	neuroinflamm	PROPN
fnp-4682	425	4	6	6	NUM
fnp-4682	425	5	,	,	PUNCT
fnp-4682	425	6	e558	e558	PROPN
fnp-4682	425	7	.	.	PUNCT
fnp-4682	426	1	https://doi.org/10.1212/nxi.0000000000000558	https://doi.org/10.1212/nxi.0000000000000558	PROPN
fnp-4682	426	2	korb	korb	PROPN
fnp-4682	426	3	,	,	PUNCT
fnp-4682	426	4	m.k	m.k	PROPN
fnp-4682	426	5	.	.	PROPN
fnp-4682	426	6	,	,	PUNCT
fnp-4682	426	7	kimonis	kimonis	PROPN
fnp-4682	426	8	,	,	PUNCT
fnp-4682	426	9	v.e	v.e	PROPN
fnp-4682	426	10	.	.	PROPN
fnp-4682	426	11	,	,	PUNCT
fnp-4682	426	12	and	and	CCONJ
fnp-4682	426	13	mozaffar	mozaffar	ADV
fnp-4682	426	14	,	,	PUNCT
fnp-4682	426	15	t.	t.	PROPN
fnp-4682	426	16	(	(	PUNCT
fnp-4682	426	17	2021	2021	NUM
fnp-4682	426	18	)	)	PUNCT
fnp-4682	426	19	.	.	PUNCT
fnp-4682	427	1	multisystem	multisystem	PROPN
fnp-4682	427	2	proteinopathy	proteinopathy	ADJ
fnp-4682	427	3	:	:	PUNCT
fnp-4682	427	4	where	where	SCONJ
fnp-4682	427	5	myopathy	myopathy	ADJ
fnp-4682	427	6	and	and	CCONJ
fnp-4682	427	7	motor	motor	NOUN
fnp-4682	427	8	neuron	neuron	PROPN
fnp-4682	427	9	disease	disease	NOUN
fnp-4682	427	10	converge	converge	VERB
fnp-4682	427	11	.	.	PUNCT
fnp-4682	428	1	muscle	muscle	NOUN
fnp-4682	428	2	nerve	nerve	NOUN
fnp-4682	428	3	63	63	NUM
fnp-4682	428	4	,	,	PUNCT
fnp-4682	428	5	442	442	NUM
fnp-4682	428	6	-	-	SYM
fnp-4682	428	7	454	454	NUM
fnp-4682	428	8	.	.	PUNCT
fnp-4682	429	1	https://doi.org/10.1002/mus.27097	https://doi.org/10.1002/mus.27097	PROPN
fnp-4682	429	2	krause	krause	PROPN
fnp-4682	429	3	,	,	PUNCT
fnp-4682	429	4	k.	k.	PROPN
fnp-4682	429	5	,	,	PUNCT
fnp-4682	429	6	eggers	eggers	PROPN
fnp-4682	429	7	,	,	PUNCT
fnp-4682	429	8	b.	b.	PROPN
fnp-4682	429	9	,	,	PUNCT
fnp-4682	429	10	uszkoreit	uszkoreit	PROPN
fnp-4682	429	11	,	,	PUNCT
fnp-4682	429	12	j.	j.	PROPN
fnp-4682	429	13	,	,	PUNCT
fnp-4682	429	14	eulitz	eulitz	PROPN
fnp-4682	429	15	,	,	PUNCT
fnp-4682	429	16	s.	s.	PROPN
fnp-4682	429	17	,	,	PUNCT
fnp-4682	429	18	rehmann	rehmann	PROPN
fnp-4682	429	19	,	,	PUNCT
fnp-4682	429	20	r.	r.	PROPN
fnp-4682	429	21	,	,	PUNCT
fnp-4682	429	22	guttsches	guttsche	NOUN
fnp-4682	429	23	,	,	PUNCT
fnp-4682	429	24	a.k	a.k	PROPN
fnp-4682	429	25	.	.	PROPN
fnp-4682	429	26	,	,	PUNCT
fnp-4682	429	27	schreiner	schreiner	PROPN
fnp-4682	429	28	,	,	PUNCT
fnp-4682	429	29	a.	a.	NOUN
fnp-4682	429	30	,	,	PUNCT
fnp-4682	429	31	van	van	PROPN
fnp-4682	429	32	der	der	NOUN
fnp-4682	429	33	ven	ven	PROPN
fnp-4682	429	34	,	,	PUNCT
fnp-4682	429	35	p.f.m	p.f.m	NOUN
fnp-4682	429	36	.	.	PROPN
fnp-4682	429	37	,	,	PUNCT
fnp-4682	429	38	furst	furst	PROPN
fnp-4682	429	39	,	,	PUNCT
fnp-4682	429	40	d.o	d.o	PROPN
fnp-4682	429	41	.	.	PROPN
fnp-4682	429	42	,	,	PUNCT
fnp-4682	429	43	marcus	marcus	PROPN
fnp-4682	429	44	,	,	PUNCT
fnp-4682	429	45	k.	k.	PROPN
fnp-4682	429	46	,	,	PUNCT
fnp-4682	429	47	et	et	PROPN
fnp-4682	429	48	al	al	PROPN
fnp-4682	429	49	.	.	PROPN
fnp-4682	429	50	(	(	PUNCT
fnp-4682	429	51	2022	2022	NUM
fnp-4682	429	52	)	)	PUNCT
fnp-4682	429	53	.	.	PUNCT
fnp-4682	430	1	target	target	NOUN
fnp-4682	430	2	formation	formation	NOUN
fnp-4682	430	3	in	in	ADP
fnp-4682	430	4	muscle	muscle	NOUN
fnp-4682	430	5	fibres	fibre	NOUN
fnp-4682	430	6	indicates	indicate	VERB
fnp-4682	430	7	reinnervation	reinnervation	NOUN
fnp-4682	430	8	a	a	DET
fnp-4682	430	9	proteomic	proteomic	ADJ
fnp-4682	430	10	study	study	NOUN
fnp-4682	430	11	in	in	ADP
fnp-4682	430	12	muscle	muscle	NOUN
fnp-4682	430	13	samples	sample	NOUN
fnp-4682	430	14	from	from	ADP
fnp-4682	430	15	peripheral	peripheral	ADJ
fnp-4682	430	16	neuropathies	neuropathy	NOUN
fnp-4682	430	17	.	.	PUNCT
fnp-4682	431	1	neuropathol	neuropathol	PROPN
fnp-4682	431	2	appl	appl	PROPN
fnp-4682	431	3	neurobiol	neurobiol	PROPN
fnp-4682	431	4	,	,	PUNCT
fnp-4682	431	5	e12853	e12853	PROPN
fnp-4682	431	6	.	.	PUNCT
fnp-4682	432	1	https://doi.org/10.1111/nan.12853	https://doi.org/10.1111/nan.12853	ADJ
fnp-4682	432	2	kurashige	kurashige	NOUN
fnp-4682	432	3	,	,	PUNCT
fnp-4682	432	4	t.	t.	PROPN
fnp-4682	432	5	,	,	PUNCT
fnp-4682	432	6	morino	morino	PROPN
fnp-4682	432	7	,	,	PUNCT
fnp-4682	432	8	h.	h.	PROPN
fnp-4682	432	9	,	,	PUNCT
fnp-4682	432	10	murao	murao	INTJ
fnp-4682	432	11	,	,	PUNCT
fnp-4682	432	12	t.	t.	PROPN
fnp-4682	432	13	,	,	PUNCT
fnp-4682	432	14	izumi	izumi	PROPN
fnp-4682	432	15	,	,	PUNCT
fnp-4682	432	16	y.	y.	PROPN
fnp-4682	432	17	,	,	PUNCT
fnp-4682	432	18	sugiura	sugiura	NOUN
fnp-4682	432	19	,	,	PUNCT
fnp-4682	432	20	t.	t.	PROPN
fnp-4682	432	21	,	,	PUNCT
fnp-4682	432	22	kuraoka	kuraoka	PROPN
fnp-4682	432	23	,	,	PUNCT
fnp-4682	432	24	k.	k.	PROPN
fnp-4682	432	25	,	,	PUNCT
fnp-4682	432	26	kawakami	kawakami	PROPN
fnp-4682	432	27	,	,	PUNCT
fnp-4682	432	28	h.	h.	PROPN
fnp-4682	432	29	,	,	PUNCT
fnp-4682	432	30	torii	torii	PROPN
fnp-4682	432	31	,	,	PUNCT
fnp-4682	432	32	t.	t.	PROPN
fnp-4682	432	33	,	,	PUNCT
fnp-4682	432	34	and	and	CCONJ
fnp-4682	432	35	maruyama	maruyama	PROPN
fnp-4682	432	36	,	,	PUNCT
fnp-4682	432	37	h.	h.	PROPN
fnp-4682	432	38	(	(	PUNCT
fnp-4682	432	39	2022	2022	NUM
fnp-4682	432	40	)	)	PUNCT
fnp-4682	432	41	.	.	PUNCT
fnp-4682	433	1	tdp-43	tdp-43	VERB
fnp-4682	433	2	accumulation	accumulation	NOUN
fnp-4682	433	3	within	within	ADP
fnp-4682	433	4	intramuscular	intramuscular	ADJ
fnp-4682	433	5	nerve	nerve	NOUN
fnp-4682	433	6	bundles	bundle	NOUN
fnp-4682	433	7	of	of	ADP
fnp-4682	433	8	patients	patient	NOUN
fnp-4682	433	9	with	with	ADP
fnp-4682	433	10	amyotrophic	amyotrophic	ADJ
fnp-4682	433	11	lateral	lateral	ADJ
fnp-4682	433	12	sclerosis	sclerosis	NOUN
fnp-4682	433	13	.	.	PUNCT
fnp-4682	434	1	jama	jama	PROPN
fnp-4682	434	2	neurol	neurol	PROPN
fnp-4682	434	3	79	79	NUM
fnp-4682	434	4	,	,	PUNCT
fnp-4682	434	5	693	693	NUM
fnp-4682	434	6	-	-	SYM
fnp-4682	434	7	701	701	NUM
fnp-4682	434	8	.	.	PUNCT
fnp-4682	435	1	https://doi.org/10.1001/jamaneurol.2022.1113	https://doi.org/10.1001/jamaneurol.2022.1113	PROPN
fnp-4682	435	2	levine	levine	PROPN
fnp-4682	435	3	,	,	PUNCT
fnp-4682	435	4	t.d	t.d	PROPN
fnp-4682	435	5	.	.	PROPN
fnp-4682	435	6	,	,	PUNCT
fnp-4682	435	7	and	and	CCONJ
fnp-4682	435	8	pestronk	pestronk	VERB
fnp-4682	435	9	,	,	PUNCT
fnp-4682	435	10	a.	a.	NOUN
fnp-4682	435	11	(	(	PUNCT
fnp-4682	435	12	1998	1998	NUM
fnp-4682	435	13	)	)	PUNCT
fnp-4682	435	14	.	.	PUNCT
fnp-4682	436	1	inflammatory	inflammatory	ADJ
fnp-4682	436	2	myopathy	myopathy	ADJ
fnp-4682	436	3	with	with	ADP
fnp-4682	436	4	cytochrome	cytochrome	ADJ
fnp-4682	436	5	oxidase	oxidase	NOUN
fnp-4682	436	6	negative	negative	ADJ
fnp-4682	436	7	muscle	muscle	NOUN
fnp-4682	436	8	fibers	fiber	NOUN
fnp-4682	436	9	:	:	PUNCT
fnp-4682	436	10	methotrexate	methotrexate	NOUN
fnp-4682	436	11	treatment	treatment	NOUN
fnp-4682	436	12	.	.	PUNCT
fnp-4682	437	1	muscle	muscle	NOUN
fnp-4682	437	2	nerve	nerve	NOUN
fnp-4682	437	3	21	21	NUM
fnp-4682	437	4	,	,	PUNCT
fnp-4682	437	5	1724	1724	NUM
fnp-4682	437	6	-	-	SYM
fnp-4682	437	7	1728	1728	NUM
fnp-4682	437	8	.	.	PUNCT
fnp-4682	438	1	https://doi.org/10.1002/(sici)1097-4598(199812)21:123.0.co;2-2	https://doi.org/10.1002/(sici)1097-4598(199812)21:123.0.co;2-2	VERB
fnp-4682	438	2	li	li	PROPN
fnp-4682	438	3	,	,	PUNCT
fnp-4682	438	4	x.	x.	PROPN
fnp-4682	438	5	,	,	PUNCT
fnp-4682	438	6	zhang	zhang	PROPN
fnp-4682	438	7	,	,	PUNCT
fnp-4682	438	8	t.	t.	PROPN
fnp-4682	438	9	,	,	PUNCT
fnp-4682	438	10	li	li	PROPN
fnp-4682	438	11	,	,	PUNCT
fnp-4682	438	12	c.	c.	PROPN
fnp-4682	438	13	,	,	PUNCT
fnp-4682	438	14	xu	xu	PROPN
fnp-4682	438	15	,	,	PUNCT
fnp-4682	438	16	w.	w.	PROPN
fnp-4682	438	17	,	,	PUNCT
fnp-4682	438	18	guan	guan	PROPN
fnp-4682	438	19	,	,	PUNCT
fnp-4682	438	20	y.	y.	PROPN
fnp-4682	438	21	,	,	PUNCT
fnp-4682	438	22	li	li	PROPN
fnp-4682	438	23	,	,	PUNCT
fnp-4682	438	24	x.	x.	PROPN
fnp-4682	438	25	,	,	PUNCT
fnp-4682	438	26	cheng	cheng	PROPN
fnp-4682	438	27	,	,	PUNCT
fnp-4682	438	28	h.	h.	PROPN
fnp-4682	438	29	,	,	PUNCT
fnp-4682	438	30	chen	chen	PROPN
fnp-4682	438	31	,	,	PUNCT
fnp-4682	438	32	s.	s.	PROPN
fnp-4682	438	33	,	,	PUNCT
fnp-4682	438	34	yang	yang	PROPN
fnp-4682	438	35	,	,	PUNCT
fnp-4682	438	36	b.	b.	PROPN
fnp-4682	438	37	,	,	PUNCT
fnp-4682	438	38	liu	liu	PROPN
fnp-4682	438	39	,	,	PUNCT
fnp-4682	438	40	y.	y.	PROPN
fnp-4682	438	41	,	,	PUNCT
fnp-4682	438	42	et	et	PROPN
fnp-4682	438	43	al	al	PROPN
fnp-4682	438	44	.	.	PROPN
fnp-4682	438	45	(	(	PUNCT
fnp-4682	438	46	2023	2023	NUM
fnp-4682	438	47	)	)	PUNCT
fnp-4682	438	48	.	.	PUNCT
fnp-4682	439	1	electrical	electrical	ADJ
fnp-4682	439	2	stimulation	stimulation	NOUN
fnp-4682	439	3	accelerates	accelerate	VERB
fnp-4682	439	4	wallerian	wallerian	ADJ
fnp-4682	439	5	degeneration	degeneration	NOUN
fnp-4682	439	6	and	and	CCONJ
fnp-4682	439	7	promotes	promote	VERB
fnp-4682	439	8	nerve	nerve	NOUN
fnp-4682	439	9	regeneration	regeneration	NOUN
fnp-4682	439	10	after	after	ADP
fnp-4682	439	11	sciatic	sciatic	ADJ
fnp-4682	439	12	nerve	nerve	NOUN
fnp-4682	439	13	injury	injury	NOUN
fnp-4682	439	14	.	.	PUNCT
fnp-4682	440	1	glia	glia	PROPN
fnp-4682	440	2	71	71	NUM
fnp-4682	440	3	,	,	PUNCT
fnp-4682	440	4	758	758	NUM
fnp-4682	440	5	-	-	SYM
fnp-4682	440	6	774	774	NUM
fnp-4682	440	7	.	.	PUNCT
fnp-4682	441	1	https://doi.org/10.1002/glia.24309	https://doi.org/10.1002/glia.24309	PROPN
fnp-4682	441	2	lukacs	lukacs	PROPN
fnp-4682	441	3	,	,	PUNCT
fnp-4682	441	4	m.	m.	NOUN
fnp-4682	441	5	,	,	PUNCT
fnp-4682	441	6	gilley	gilley	PROPN
fnp-4682	441	7	,	,	PUNCT
fnp-4682	441	8	j.	j.	PROPN
fnp-4682	441	9	,	,	PUNCT
fnp-4682	441	10	zhu	zhu	PROPN
fnp-4682	441	11	,	,	PUNCT
fnp-4682	441	12	y.	y.	PROPN
fnp-4682	441	13	,	,	PUNCT
fnp-4682	441	14	orsomando	orsomando	PROPN
fnp-4682	441	15	,	,	PUNCT
fnp-4682	441	16	g.	g.	PROPN
fnp-4682	441	17	,	,	PUNCT
fnp-4682	441	18	angeletti	angeletti	PROPN
fnp-4682	441	19	,	,	PUNCT
fnp-4682	441	20	c.	c.	PROPN
fnp-4682	441	21	,	,	PUNCT
fnp-4682	441	22	liu	liu	PROPN
fnp-4682	441	23	,	,	PUNCT
fnp-4682	441	24	j.	j.	PROPN
fnp-4682	441	25	,	,	PUNCT
fnp-4682	441	26	yang	yang	PROPN
fnp-4682	441	27	,	,	PUNCT
fnp-4682	441	28	x.	x.	PROPN
fnp-4682	441	29	,	,	PUNCT
fnp-4682	441	30	park	park	PROPN
fnp-4682	441	31	,	,	PUNCT
fnp-4682	441	32	j.	j.	PROPN
fnp-4682	441	33	,	,	PUNCT
fnp-4682	441	34	hopkin	hopkin	PROPN
fnp-4682	441	35	,	,	PUNCT
fnp-4682	441	36	r.j	r.j	PROPN
fnp-4682	441	37	.	.	PROPN
fnp-4682	441	38	,	,	PUNCT
fnp-4682	441	39	coleman	coleman	PROPN
fnp-4682	441	40	,	,	PUNCT
fnp-4682	441	41	m.p	m.p	PROPN
fnp-4682	441	42	.	.	PROPN
fnp-4682	441	43	,	,	PUNCT
fnp-4682	441	44	et	et	PROPN
fnp-4682	441	45	al	al	PROPN
fnp-4682	441	46	.	.	PROPN
fnp-4682	441	47	(	(	PUNCT
fnp-4682	441	48	2019	2019	NUM
fnp-4682	441	49	)	)	PUNCT
fnp-4682	441	50	.	.	PUNCT
fnp-4682	442	1	severe	severe	ADJ
fnp-4682	442	2	biallelic	biallelic	ADJ
fnp-4682	442	3	loss	loss	NOUN
fnp-4682	442	4	-	-	PUNCT
fnp-4682	442	5	of	of	ADP
fnp-4682	442	6	-	-	PUNCT
fnp-4682	442	7	function	function	NOUN
fnp-4682	442	8	mutations	mutation	NOUN
fnp-4682	442	9	in	in	ADP
fnp-4682	442	10	nicotinamide	nicotinamide	NOUN
fnp-4682	442	11	mononucleotide	mononucleotide	NOUN
fnp-4682	442	12	adenylyltransferase	adenylyltransferase	ADJ
fnp-4682	442	13	2	2	NUM
fnp-4682	442	14	(	(	PUNCT
fnp-4682	442	15	nmnat2	nmnat2	NOUN
fnp-4682	442	16	)	)	PUNCT
fnp-4682	442	17	in	in	ADP
fnp-4682	442	18	two	two	NUM
fnp-4682	442	19	fetuses	fetus	NOUN
fnp-4682	442	20	with	with	ADP
fnp-4682	442	21	fetal	fetal	ADJ
fnp-4682	442	22	akinesia	akinesia	NOUN
fnp-4682	442	23	deformation	deformation	NOUN
fnp-4682	442	24	sequence	sequence	NOUN
fnp-4682	442	25	.	.	PUNCT
fnp-4682	443	1	exp	exp	NOUN
fnp-4682	443	2	neurol	neurol	NOUN
fnp-4682	443	3	320	320	NUM
fnp-4682	443	4	,	,	PUNCT
fnp-4682	443	5	112961	112961	NUM
fnp-4682	443	6	.	.	PUNCT
fnp-4682	444	1	https://doi.org/10.1016/j.expneurol.2019.112961	https://doi.org/10.1016/j.expneurol.2019.112961	ADJ
fnp-4682	444	2	margeta	margeta	NOUN
fnp-4682	444	3	,	,	PUNCT
fnp-4682	444	4	m.	m.	NOUN
fnp-4682	444	5	(	(	PUNCT
fnp-4682	444	6	2020	2020	NUM
fnp-4682	444	7	)	)	PUNCT
fnp-4682	444	8	.	.	PUNCT
fnp-4682	445	1	top	top	ADJ
fnp-4682	445	2	ten	ten	NUM
fnp-4682	445	3	discoveries	discovery	NOUN
fnp-4682	445	4	of	of	ADP
fnp-4682	445	5	the	the	DET
fnp-4682	445	6	year	year	NOUN
fnp-4682	445	7	:	:	PUNCT
fnp-4682	445	8	neuromuscular	neuromuscular	ADJ
fnp-4682	445	9	disease	disease	NOUN
fnp-4682	445	10	.	.	PUNCT
fnp-4682	446	1	free	free	ADJ
fnp-4682	446	2	neuropathol	neuropathol	NOUN
fnp-4682	446	3	1	1	NUM
fnp-4682	446	4	,	,	PUNCT
fnp-4682	446	5	4	4	NUM
fnp-4682	446	6	.	.	PUNCT
fnp-4682	447	1	https://doi.org/10.17879/freeneuropathology-2020-2627	https://doi.org/10.17879/freeneuropathology-2020-2627	PROPN
fnp-4682	447	2	margeta	margeta	NOUN
fnp-4682	447	3	,	,	PUNCT
fnp-4682	447	4	m.	m.	NOUN
fnp-4682	447	5	(	(	PUNCT
fnp-4682	447	6	2021	2021	NUM
fnp-4682	447	7	)	)	PUNCT
fnp-4682	447	8	.	.	PUNCT
fnp-4682	448	1	neuromuscular	neuromuscular	ADJ
fnp-4682	448	2	disease	disease	NOUN
fnp-4682	448	3	:	:	PUNCT
fnp-4682	448	4	2021	2021	NUM
fnp-4682	448	5	update	update	NOUN
fnp-4682	448	6	.	.	PUNCT
fnp-4682	449	1	free	free	ADJ
fnp-4682	449	2	neuropathol	neuropathol	NOUN
fnp-4682	449	3	2	2	NUM
fnp-4682	449	4	,	,	PUNCT
fnp-4682	449	5	3	3	NUM
fnp-4682	449	6	.	.	PUNCT
fnp-4682	450	1	https://doi.org/10.17879/freeneuropathology-2021-3236	https://doi.org/10.17879/freeneuropathology-2021-3236	PROPN
fnp-4682	450	2	margeta	margeta	NOUN
fnp-4682	450	3	,	,	PUNCT
fnp-4682	450	4	m.	m.	NOUN
fnp-4682	450	5	(	(	PUNCT
fnp-4682	450	6	2022	2022	NUM
fnp-4682	450	7	)	)	PUNCT
fnp-4682	450	8	.	.	PUNCT
fnp-4682	451	1	neuromuscular	neuromuscular	ADJ
fnp-4682	451	2	disease	disease	NOUN
fnp-4682	451	3	:	:	PUNCT
fnp-4682	451	4	2022	2022	NUM
fnp-4682	451	5	update	update	NOUN
fnp-4682	451	6	.	.	PUNCT
fnp-4682	452	1	free	free	ADJ
fnp-4682	452	2	neuropathol	neuropathol	NOUN
fnp-4682	452	3	3	3	NUM
fnp-4682	452	4	,	,	PUNCT
fnp-4682	452	5	5	5	NUM
fnp-4682	452	6	.	.	PUNCT
fnp-4682	453	1	https://doi.org/10.17879/freeneuropathology-2022-3805	https://doi.org/10.17879/freeneuropathology-2022-3805	PROPN
fnp-4682	453	2	martin	martin	PROPN
fnp-4682	453	3	-	-	PUNCT
fnp-4682	453	4	aguilar	aguilar	PROPN
fnp-4682	453	5	,	,	PUNCT
fnp-4682	453	6	l.	l.	PROPN
fnp-4682	453	7	,	,	PUNCT
fnp-4682	453	8	lleixa	lleixa	PROPN
fnp-4682	453	9	,	,	PUNCT
fnp-4682	453	10	c.	c.	PROPN
fnp-4682	453	11	,	,	PUNCT
fnp-4682	453	12	and	and	CCONJ
fnp-4682	453	13	pascual	pascual	NOUN
fnp-4682	453	14	-	-	PUNCT
fnp-4682	453	15	goni	goni	NOUN
fnp-4682	453	16	,	,	PUNCT
fnp-4682	453	17	e.	e.	PROPN
fnp-4682	453	18	(	(	PUNCT
fnp-4682	453	19	2022	2022	NUM
fnp-4682	453	20	)	)	PUNCT
fnp-4682	453	21	.	.	PUNCT
fnp-4682	454	1	autoimmune	autoimmune	ADJ
fnp-4682	454	2	nodopathies	nodopathie	NOUN
fnp-4682	454	3	,	,	PUNCT
fnp-4682	454	4	an	an	DET
fnp-4682	454	5	emerging	emerge	VERB
fnp-4682	454	6	diagnostic	diagnostic	ADJ
fnp-4682	454	7	category	category	NOUN
fnp-4682	454	8	.	.	PUNCT
fnp-4682	455	1	curr	curr	PROPN
fnp-4682	455	2	opin	opin	PROPN
fnp-4682	455	3	neurol	neurol	NOUN
fnp-4682	455	4	35	35	NUM
fnp-4682	455	5	,	,	PUNCT
fnp-4682	455	6	579	579	NUM
fnp-4682	455	7	-	-	SYM
fnp-4682	455	8	585	585	NUM
fnp-4682	455	9	.	.	PUNCT
fnp-4682	456	1	https://doi.org/10.1097/wco.0000000000001107	https://doi.org/10.1097/wco.0000000000001107	PROPN
fnp-4682	456	2	mcgonigal	mcgonigal	ADJ
fnp-4682	456	3	,	,	PUNCT
fnp-4682	456	4	r.	r.	PROPN
fnp-4682	456	5	,	,	PUNCT
fnp-4682	456	6	campbell	campbell	PROPN
fnp-4682	456	7	,	,	PUNCT
fnp-4682	456	8	c.i	c.i	PROPN
fnp-4682	456	9	.	.	PROPN
fnp-4682	456	10	,	,	PUNCT
fnp-4682	456	11	barrie	barrie	PROPN
fnp-4682	456	12	,	,	PUNCT
fnp-4682	456	13	j.a	j.a	PROPN
fnp-4682	456	14	.	.	PROPN
fnp-4682	456	15	,	,	PUNCT
fnp-4682	456	16	yao	yao	PROPN
fnp-4682	456	17	,	,	PUNCT
fnp-4682	456	18	d.	d.	PROPN
fnp-4682	456	19	,	,	PUNCT
fnp-4682	456	20	cunningham	cunningham	PROPN
fnp-4682	456	21	,	,	PUNCT
fnp-4682	456	22	m.e	m.e	PROPN
fnp-4682	456	23	.	.	PROPN
fnp-4682	456	24	,	,	PUNCT
fnp-4682	456	25	crawford	crawford	PROPN
fnp-4682	456	26	,	,	PUNCT
fnp-4682	456	27	c.l	c.l	PROPN
fnp-4682	456	28	.	.	PROPN
fnp-4682	456	29	,	,	PUNCT
fnp-4682	456	30	rinaldi	rinaldi	PROPN
fnp-4682	456	31	,	,	PUNCT
fnp-4682	456	32	s.	s.	PROPN
fnp-4682	456	33	,	,	PUNCT
fnp-4682	456	34	rowan	rowan	PROPN
fnp-4682	456	35	,	,	PUNCT
fnp-4682	456	36	e.g.	e.g.	ADV
fnp-4682	456	37	,	,	PUNCT
fnp-4682	456	38	and	and	CCONJ
fnp-4682	456	39	willison	willison	PROPN
fnp-4682	456	40	,	,	PUNCT
fnp-4682	456	41	h.j	h.j	PROPN
fnp-4682	456	42	.	.	PROPN
fnp-4682	456	43	(	(	PUNCT
fnp-4682	456	44	2022	2022	NUM
fnp-4682	456	45	)	)	PUNCT
fnp-4682	456	46	.	.	PUNCT
fnp-4682	457	1	schwann	schwann	PROPN
fnp-4682	457	2	cell	cell	NOUN
fnp-4682	457	3	nodal	nodal	NOUN
fnp-4682	457	4	membrane	membrane	NOUN
fnp-4682	457	5	disruption	disruption	NOUN
fnp-4682	457	6	triggers	trigger	NOUN
fnp-4682	457	7	bystander	bystander	VERB
fnp-4682	457	8	axonal	axonal	ADJ
fnp-4682	457	9	degeneration	degeneration	NOUN
fnp-4682	457	10	in	in	ADP
fnp-4682	457	11	a	a	DET
fnp-4682	457	12	guillain	guillain	NOUN
fnp-4682	457	13	-	-	PUNCT
fnp-4682	457	14	barre	barre	NOUN
fnp-4682	457	15	syndrome	syndrome	PROPN
fnp-4682	457	16	mouse	mouse	PROPN
fnp-4682	457	17	model	model	NOUN
fnp-4682	457	18	.	.	PUNCT
fnp-4682	458	1	j	j	PROPN
fnp-4682	458	2	clin	clin	PROPN
fnp-4682	458	3	invest	invest	VERB
fnp-4682	458	4	132	132	NUM
fnp-4682	458	5	,	,	PUNCT
fnp-4682	458	6	e158524	e158524	PROPN
fnp-4682	458	7	.	.	PUNCT
fnp-4682	459	1	https://doi.org/10.1172/jci158524	https://doi.org/10.1172/jci158524	PROPN
fnp-4682	459	2	mocciaro	mocciaro	PROPN
fnp-4682	459	3	,	,	PUNCT
fnp-4682	459	4	e.	e.	PROPN
fnp-4682	459	5	,	,	PUNCT
fnp-4682	459	6	runfola	runfola	PROPN
fnp-4682	459	7	,	,	PUNCT
fnp-4682	459	8	v.	v.	ADV
fnp-4682	459	9	,	,	PUNCT
fnp-4682	459	10	ghezzi	ghezzi	NOUN
fnp-4682	459	11	,	,	PUNCT
fnp-4682	459	12	p.	p.	NOUN
fnp-4682	459	13	,	,	PUNCT
fnp-4682	459	14	pannese	pannese	PROPN
fnp-4682	459	15	,	,	PUNCT
fnp-4682	459	16	m.	m.	NOUN
fnp-4682	459	17	,	,	PUNCT
fnp-4682	459	18	and	and	CCONJ
fnp-4682	459	19	gabellini	gabellini	PROPN
fnp-4682	459	20	,	,	PUNCT
fnp-4682	459	21	d.	d.	PROPN
fnp-4682	459	22	(	(	PUNCT
fnp-4682	459	23	2021	2021	NUM
fnp-4682	459	24	)	)	PUNCT
fnp-4682	459	25	.	.	PUNCT
fnp-4682	460	1	dux4	dux4	NOUN
fnp-4682	460	2	role	role	NOUN
fnp-4682	460	3	in	in	ADP
fnp-4682	460	4	normal	normal	ADJ
fnp-4682	460	5	physiology	physiology	NOUN
fnp-4682	460	6	and	and	CCONJ
fnp-4682	460	7	in	in	ADP
fnp-4682	460	8	fshd	fshd	ADJ
fnp-4682	460	9	muscular	muscular	ADJ
fnp-4682	460	10	dystrophy	dystrophy	NOUN
fnp-4682	460	11	.	.	PUNCT
fnp-4682	461	1	cells	cell	NOUN
fnp-4682	461	2	10	10	NUM
fnp-4682	461	3	,	,	PUNCT
fnp-4682	461	4	3322	3322	NUM
fnp-4682	461	5	.	.	PUNCT
fnp-4682	462	1	https://doi.org/10.3390/cells10123322	https://doi.org/10.3390/cells10123322	PROPN
fnp-4682	462	2	oaklander	oaklander	PROPN
fnp-4682	462	3	,	,	PUNCT
fnp-4682	462	4	a.l	a.l	PROPN
fnp-4682	462	5	.	.	PROPN
fnp-4682	462	6	,	,	PUNCT
fnp-4682	462	7	mills	mills	PROPN
fnp-4682	462	8	,	,	PUNCT
fnp-4682	462	9	a.j	a.j	PROPN
fnp-4682	462	10	.	.	PROPN
fnp-4682	462	11	,	,	PUNCT
fnp-4682	462	12	kelley	kelley	PROPN
fnp-4682	462	13	,	,	PUNCT
fnp-4682	462	14	m.	m.	NOUN
fnp-4682	462	15	,	,	PUNCT
fnp-4682	462	16	toran	toran	PROPN
fnp-4682	462	17	,	,	PUNCT
fnp-4682	462	18	l.s	l.s	PROPN
fnp-4682	462	19	.	.	PROPN
fnp-4682	462	20	,	,	PUNCT
fnp-4682	462	21	smith	smith	PROPN
fnp-4682	462	22	,	,	PUNCT
fnp-4682	462	23	b.	b.	PROPN
fnp-4682	462	24	,	,	PUNCT
fnp-4682	462	25	dalakas	dalakas	PROPN
fnp-4682	462	26	,	,	PUNCT
fnp-4682	462	27	m.c	m.c	PROPN
fnp-4682	462	28	.	.	PROPN
fnp-4682	462	29	,	,	PUNCT
fnp-4682	462	30	and	and	CCONJ
fnp-4682	462	31	nath	nath	NOUN
fnp-4682	462	32	,	,	PUNCT
fnp-4682	462	33	a.	a.	NOUN
fnp-4682	462	34	(	(	PUNCT
fnp-4682	462	35	2022	2022	NUM
fnp-4682	462	36	)	)	PUNCT
fnp-4682	462	37	.	.	PUNCT
fnp-4682	463	1	peripheral	peripheral	ADJ
fnp-4682	463	2	neuropathy	neuropathy	ADJ
fnp-4682	463	3	evaluations	evaluation	NOUN
fnp-4682	463	4	of	of	ADP
fnp-4682	463	5	patients	patient	NOUN
fnp-4682	463	6	with	with	ADP
fnp-4682	463	7	prolonged	prolonged	ADJ
fnp-4682	463	8	long	long	ADJ
fnp-4682	463	9	covid	covid	PROPN
fnp-4682	463	10	.	.	PUNCT
fnp-4682	464	1	neurol	neurol	PROPN
fnp-4682	464	2	neuroimmunol	neuroimmunol	PROPN
fnp-4682	464	3	neuroinflamm	neuroinflamm	PROPN
fnp-4682	464	4	9	9	NUM
fnp-4682	464	5	,	,	PUNCT
fnp-4682	464	6	e1146	e1146	PROPN
fnp-4682	464	7	.	.	PUNCT
fnp-4682	465	1	https://doi.org/10.1212/nxi.0000000000001146	https://doi.org/10.1212/nxi.0000000000001146	NOUN
fnp-4682	465	2	osterloh	osterloh	PROPN
fnp-4682	465	3	,	,	PUNCT
fnp-4682	465	4	j.m	j.m	PROPN
fnp-4682	465	5	.	.	PROPN
fnp-4682	465	6	,	,	PUNCT
fnp-4682	465	7	yang	yang	PROPN
fnp-4682	465	8	,	,	PUNCT
fnp-4682	465	9	j.	j.	PROPN
fnp-4682	465	10	,	,	PUNCT
fnp-4682	465	11	rooney	rooney	PROPN
fnp-4682	465	12	,	,	PUNCT
fnp-4682	465	13	t.m	t.m	PROPN
fnp-4682	465	14	.	.	PROPN
fnp-4682	465	15	,	,	PUNCT
fnp-4682	465	16	fox	fox	PROPN
fnp-4682	465	17	,	,	PUNCT
fnp-4682	465	18	a.n	a.n	PROPN
fnp-4682	465	19	.	.	PROPN
fnp-4682	465	20	,	,	PUNCT
fnp-4682	465	21	adalbert	adalbert	PROPN
fnp-4682	465	22	,	,	PUNCT
fnp-4682	465	23	r.	r.	PROPN
fnp-4682	465	24	,	,	PUNCT
fnp-4682	465	25	powell	powell	PROPN
fnp-4682	465	26	,	,	PUNCT
fnp-4682	465	27	e.h	e.h	PROPN
fnp-4682	465	28	.	.	PROPN
fnp-4682	465	29	,	,	PUNCT
fnp-4682	465	30	sheehan	sheehan	PROPN
fnp-4682	465	31	,	,	PUNCT
fnp-4682	465	32	a.e	a.e	PROPN
fnp-4682	465	33	.	.	PROPN
fnp-4682	465	34	,	,	PUNCT
fnp-4682	465	35	avery	avery	PROPN
fnp-4682	465	36	,	,	PUNCT
fnp-4682	465	37	m.a	m.a	PROPN
fnp-4682	465	38	.	.	PROPN
fnp-4682	465	39	,	,	PUNCT
fnp-4682	465	40	hackett	hackett	PROPN
fnp-4682	465	41	,	,	PUNCT
fnp-4682	465	42	r.	r.	PROPN
fnp-4682	465	43	,	,	PUNCT
fnp-4682	465	44	logan	logan	PROPN
fnp-4682	465	45	,	,	PUNCT
fnp-4682	465	46	m.a	m.a	PROPN
fnp-4682	465	47	.	.	PROPN
fnp-4682	465	48	,	,	PUNCT
fnp-4682	465	49	et	et	PROPN
fnp-4682	465	50	al	al	PROPN
fnp-4682	465	51	.	.	PUNCT
fnp-4682	465	52	(	(	PUNCT
fnp-4682	465	53	2012	2012	NUM
fnp-4682	465	54	)	)	PUNCT
fnp-4682	465	55	.	.	PUNCT
fnp-4682	466	1	dsarm	dsarm	PROPN
fnp-4682	466	2	/	/	SYM
fnp-4682	466	3	sarm1	sarm1	PROPN
fnp-4682	466	4	is	be	AUX
fnp-4682	466	5	required	require	VERB
fnp-4682	466	6	for	for	ADP
fnp-4682	466	7	activation	activation	NOUN
fnp-4682	466	8	of	of	ADP
fnp-4682	466	9	an	an	DET
fnp-4682	466	10	injury	injury	NOUN
fnp-4682	466	11	-	-	PUNCT
fnp-4682	466	12	induced	induce	VERB
fnp-4682	466	13	axon	axon	NOUN
fnp-4682	466	14	death	death	NOUN
fnp-4682	466	15	pathway	pathway	NOUN
fnp-4682	466	16	.	.	PUNCT
fnp-4682	467	1	science	science	NOUN
fnp-4682	467	2	337	337	NUM
fnp-4682	467	3	,	,	PUNCT
fnp-4682	467	4	481	481	NUM
fnp-4682	467	5	-	-	SYM
fnp-4682	467	6	484	484	NUM
fnp-4682	467	7	.	.	PUNCT
fnp-4682	468	1	https://doi.org/10.1126/science.1223899	https://doi.org/10.1126/science.1223899	PROPN
fnp-4682	468	2	riva	riva	PROPN
fnp-4682	468	3	,	,	PUNCT
fnp-4682	468	4	n.	n.	NOUN
fnp-4682	468	5	,	,	PUNCT
fnp-4682	468	6	gentile	gentile	NOUN
fnp-4682	468	7	,	,	PUNCT
fnp-4682	468	8	f.	f.	PROPN
fnp-4682	468	9	,	,	PUNCT
fnp-4682	468	10	cerri	cerri	PROPN
fnp-4682	468	11	,	,	PUNCT
fnp-4682	468	12	f.	f.	PROPN
fnp-4682	468	13	,	,	PUNCT
fnp-4682	468	14	gallia	gallia	PROPN
fnp-4682	468	15	,	,	PUNCT
fnp-4682	468	16	f.	f.	PROPN
fnp-4682	468	17	,	,	PUNCT
fnp-4682	468	18	podini	podini	PROPN
fnp-4682	468	19	,	,	PUNCT
fnp-4682	468	20	p.	p.	PROPN
fnp-4682	468	21	,	,	PUNCT
fnp-4682	468	22	dina	dina	PROPN
fnp-4682	468	23	,	,	PUNCT
fnp-4682	468	24	g.	g.	PROPN
fnp-4682	468	25	,	,	PUNCT
fnp-4682	468	26	falzone	falzone	PROPN
fnp-4682	468	27	,	,	PUNCT
fnp-4682	468	28	y.m	y.m	PROPN
fnp-4682	468	29	.	.	PROPN
fnp-4682	468	30	,	,	PUNCT
fnp-4682	468	31	fazio	fazio	PROPN
fnp-4682	468	32	,	,	PUNCT
fnp-4682	468	33	r.	r.	PROPN
fnp-4682	468	34	,	,	PUNCT
fnp-4682	468	35	lunetta	lunetta	PROPN
fnp-4682	468	36	,	,	PUNCT
fnp-4682	468	37	c.	c.	PROPN
fnp-4682	468	38	,	,	PUNCT
fnp-4682	468	39	calvo	calvo	PROPN
fnp-4682	468	40	,	,	PUNCT
fnp-4682	468	41	a.	a.	PROPN
fnp-4682	468	42	,	,	PUNCT
fnp-4682	468	43	et	et	PROPN
fnp-4682	468	44	al	al	PROPN
fnp-4682	468	45	.	.	PROPN
fnp-4682	469	1	(	(	PUNCT
fnp-4682	469	2	2022	2022	NUM
fnp-4682	469	3	)	)	PUNCT
fnp-4682	469	4	.	.	PUNCT
fnp-4682	470	1	phosphorylated	phosphorylate	VERB
fnp-4682	470	2	tdp-43	tdp-43	NOUN
fnp-4682	470	3	aggregates	aggregate	NOUN
fnp-4682	470	4	in	in	ADP
fnp-4682	470	5	peripheral	peripheral	ADJ
fnp-4682	470	6	motor	motor	NOUN
fnp-4682	470	7	nerves	nerve	NOUN
fnp-4682	470	8	of	of	ADP
fnp-4682	470	9	patients	patient	NOUN
fnp-4682	470	10	with	with	ADP
fnp-4682	470	11	amyotrophic	amyotrophic	ADJ
fnp-4682	470	12	lateral	lateral	ADJ
fnp-4682	470	13	sclerosis	sclerosis	NOUN
fnp-4682	470	14	.	.	PUNCT
fnp-4682	471	1	brain	brain	PROPN
fnp-4682	471	2	145	145	NUM
fnp-4682	471	3	,	,	PUNCT
fnp-4682	471	4	276	276	NUM
fnp-4682	471	5	-	-	SYM
fnp-4682	471	6	284	284	NUM
fnp-4682	471	7	.	.	PUNCT
fnp-4682	472	1	https://doi.org/10.1093/brain/awab285	https://doi.org/10.1093/brain/awab285	PROPN
fnp-4682	472	2	sarparanta	sarparanta	PROPN
fnp-4682	472	3	,	,	PUNCT
fnp-4682	472	4	j.	j.	PROPN
fnp-4682	472	5	,	,	PUNCT
fnp-4682	472	6	jonson	jonson	PROPN
fnp-4682	472	7	,	,	PUNCT
fnp-4682	472	8	p.h	p.h	PROPN
fnp-4682	472	9	.	.	PROPN
fnp-4682	472	10	,	,	PUNCT
fnp-4682	472	11	kawan	kawan	PROPN
fnp-4682	472	12	,	,	PUNCT
fnp-4682	472	13	s.	s.	PROPN
fnp-4682	472	14	,	,	PUNCT
fnp-4682	472	15	and	and	CCONJ
fnp-4682	472	16	udd	udd	PROPN
fnp-4682	472	17	,	,	PUNCT
fnp-4682	472	18	b.	b.	PROPN
fnp-4682	472	19	(	(	PUNCT
fnp-4682	472	20	2020	2020	NUM
fnp-4682	472	21	)	)	PUNCT
fnp-4682	472	22	.	.	PUNCT
fnp-4682	473	1	neuromuscular	neuromuscular	ADJ
fnp-4682	473	2	diseases	disease	NOUN
fnp-4682	473	3	due	due	ADJ
fnp-4682	473	4	to	to	ADP
fnp-4682	473	5	chaperone	chaperone	NOUN
fnp-4682	473	6	mutations	mutation	NOUN
fnp-4682	473	7	:	:	PUNCT
fnp-4682	473	8	a	a	DET
fnp-4682	473	9	review	review	NOUN
fnp-4682	473	10	and	and	CCONJ
fnp-4682	473	11	some	some	DET
fnp-4682	473	12	new	new	ADJ
fnp-4682	473	13	results	result	NOUN
fnp-4682	473	14	.	.	PUNCT
fnp-4682	474	1	int	int	PROPN
fnp-4682	474	2	j	j	PROPN
fnp-4682	474	3	mol	mol	ADP
fnp-4682	474	4	sci	sci	PROPN
fnp-4682	474	5	21	21	NUM
fnp-4682	474	6	,	,	PUNCT
fnp-4682	474	7	1409	1409	NUM
fnp-4682	474	8	.	.	PUNCT
fnp-4682	475	1	https://doi.org/10.3390/ijms21041409	https://doi.org/10.3390/ijms21041409	PROPN
fnp-4682	475	2	schiaffino	schiaffino	PROPN
fnp-4682	475	3	,	,	PUNCT
fnp-4682	475	4	s.	s.	PROPN
fnp-4682	475	5	,	,	PUNCT
fnp-4682	475	6	rossi	rossi	PROPN
fnp-4682	475	7	,	,	PUNCT
fnp-4682	475	8	a.c	a.c	PROPN
fnp-4682	475	9	.	.	PROPN
fnp-4682	475	10	,	,	PUNCT
fnp-4682	475	11	smerdu	smerdu	PROPN
fnp-4682	475	12	,	,	PUNCT
fnp-4682	475	13	v.	v.	NOUN
fnp-4682	475	14	,	,	PUNCT
fnp-4682	475	15	leinwand	leinwand	NOUN
fnp-4682	475	16	,	,	PUNCT
fnp-4682	475	17	l.a	l.a	PROPN
fnp-4682	475	18	.	.	PROPN
fnp-4682	475	19	,	,	PUNCT
fnp-4682	475	20	and	and	CCONJ
fnp-4682	475	21	reggiani	reggiani	NOUN
fnp-4682	475	22	,	,	PUNCT
fnp-4682	475	23	c.	c.	NOUN
fnp-4682	475	24	(	(	PUNCT
fnp-4682	475	25	2015	2015	NUM
fnp-4682	475	26	)	)	PUNCT
fnp-4682	475	27	.	.	PUNCT
fnp-4682	476	1	developmental	developmental	ADJ
fnp-4682	476	2	myosins	myosin	NOUN
fnp-4682	476	3	:	:	PUNCT
fnp-4682	476	4	expression	expression	NOUN
fnp-4682	476	5	patterns	pattern	NOUN
fnp-4682	476	6	and	and	CCONJ
fnp-4682	476	7	functional	functional	ADJ
fnp-4682	476	8	significance	significance	NOUN
fnp-4682	476	9	.	.	PUNCT
fnp-4682	477	1	skelet	skelet	ADJ
fnp-4682	477	2	muscle	muscle	NOUN
fnp-4682	477	3	5	5	NUM
fnp-4682	477	4	,	,	PUNCT
fnp-4682	477	5	22	22	NUM
fnp-4682	477	6	.	.	PUNCT
fnp-4682	478	1	https://doi.org/10.1186/s13395-015-0046-6	https://doi.org/10.1186/s13395-015-0046-6	VERB
fnp-4682	478	2	sewry	sewry	NOUN
fnp-4682	478	3	,	,	PUNCT
fnp-4682	478	4	c.a	c.a	PROPN
fnp-4682	478	5	.	.	PROPN
fnp-4682	478	6	,	,	PUNCT
fnp-4682	478	7	feng	feng	PROPN
fnp-4682	478	8	,	,	PUNCT
fnp-4682	478	9	l.	l.	PROPN
fnp-4682	478	10	,	,	PUNCT
fnp-4682	478	11	chambers	chamber	NOUN
fnp-4682	478	12	,	,	PUNCT
fnp-4682	478	13	d.	d.	PROPN
fnp-4682	478	14	,	,	PUNCT
fnp-4682	478	15	matthews	matthews	PROPN
fnp-4682	478	16	,	,	PUNCT
fnp-4682	478	17	e.	e.	PROPN
fnp-4682	478	18	,	,	PUNCT
fnp-4682	478	19	and	and	CCONJ
fnp-4682	478	20	phadke	phadke	NOUN
fnp-4682	478	21	,	,	PUNCT
fnp-4682	478	22	r.	r.	PROPN
fnp-4682	478	23	(	(	PUNCT
fnp-4682	478	24	2021	2021	NUM
fnp-4682	478	25	)	)	PUNCT
fnp-4682	478	26	.	.	PUNCT
fnp-4682	479	1	importance	importance	NOUN
fnp-4682	479	2	of	of	ADP
fnp-4682	479	3	immunohistochemical	immunohistochemical	ADJ
fnp-4682	479	4	evaluation	evaluation	NOUN
fnp-4682	479	5	of	of	ADP
fnp-4682	479	6	developmentally	developmentally	ADV
fnp-4682	479	7	regulated	regulated	ADJ
fnp-4682	479	8	myosin	myosin	NOUN
fnp-4682	479	9	heavy	heavy	ADJ
fnp-4682	479	10	chains	chain	NOUN
fnp-4682	479	11	in	in	ADP
fnp-4682	479	12	human	human	ADJ
fnp-4682	479	13	muscle	muscle	NOUN
fnp-4682	479	14	biopsies	biopsy	NOUN
fnp-4682	479	15	.	.	PUNCT
fnp-4682	480	1	neuromuscul	neuromuscul	PROPN
fnp-4682	480	2	disord	disord	PROPN
fnp-4682	480	3	31	31	NUM
fnp-4682	480	4	,	,	PUNCT
fnp-4682	480	5	371	371	NUM
fnp-4682	480	6	-	-	SYM
fnp-4682	480	7	384	384	NUM
fnp-4682	480	8	.	.	PUNCT
fnp-4682	481	1	https://doi.org/10.1016/j.nmd.2021.02.007	https://doi.org/10.1016/j.nmd.2021.02.007	PROPN
fnp-4682	481	2	shi	shi	PROPN
fnp-4682	481	3	,	,	PUNCT
fnp-4682	481	4	y.	y.	PROPN
fnp-4682	481	5	,	,	PUNCT
fnp-4682	481	6	kerry	kerry	PROPN
fnp-4682	481	7	,	,	PUNCT
fnp-4682	481	8	p.s	p.s	PROPN
fnp-4682	481	9	.	.	PROPN
fnp-4682	481	10	,	,	PUNCT
fnp-4682	481	11	nanson	nanson	NOUN
fnp-4682	481	12	,	,	PUNCT
fnp-4682	481	13	j.d	j.d	PROPN
fnp-4682	481	14	.	.	PROPN
fnp-4682	481	15	,	,	PUNCT
fnp-4682	481	16	bosanac	bosanac	NOUN
fnp-4682	481	17	,	,	PUNCT
fnp-4682	481	18	t.	t.	PROPN
fnp-4682	481	19	,	,	PUNCT
fnp-4682	481	20	sasaki	sasaki	PROPN
fnp-4682	481	21	,	,	PUNCT
fnp-4682	481	22	y.	y.	PROPN
fnp-4682	481	23	,	,	PUNCT
fnp-4682	481	24	krauss	krauss	PROPN
fnp-4682	481	25	,	,	PUNCT
fnp-4682	481	26	r.	r.	PROPN
fnp-4682	481	27	,	,	PUNCT
fnp-4682	481	28	saikot	saikot	NOUN
fnp-4682	481	29	,	,	PUNCT
fnp-4682	481	30	f.k	f.k	PROPN
fnp-4682	481	31	.	.	PROPN
fnp-4682	481	32	,	,	PUNCT
fnp-4682	481	33	adams	adams	PROPN
fnp-4682	481	34	,	,	PUNCT
fnp-4682	481	35	s.e	s.e	PROPN
fnp-4682	481	36	.	.	PROPN
fnp-4682	481	37	,	,	PUNCT
fnp-4682	481	38	mosaiab	mosaiab	PROPN
fnp-4682	481	39	,	,	PUNCT
fnp-4682	481	40	t.	t.	PROPN
fnp-4682	481	41	,	,	PUNCT
fnp-4682	481	42	masic	masic	ADJ
fnp-4682	481	43	,	,	PUNCT
fnp-4682	481	44	v.	v.	PROPN
fnp-4682	481	45	,	,	PUNCT
fnp-4682	481	46	et	et	PROPN
fnp-4682	481	47	al	al	PROPN
fnp-4682	481	48	.	.	PROPN
fnp-4682	481	49	(	(	PUNCT
fnp-4682	481	50	2022	2022	NUM
fnp-4682	481	51	)	)	PUNCT
fnp-4682	481	52	.	.	PUNCT
fnp-4682	482	1	structural	structural	ADJ
fnp-4682	482	2	basis	basis	NOUN
fnp-4682	482	3	of	of	ADP
fnp-4682	482	4	sarm1	sarm1	PROPN
fnp-4682	482	5	activation	activation	NOUN
fnp-4682	482	6	,	,	PUNCT
fnp-4682	482	7	substrate	substrate	NOUN
fnp-4682	482	8	recognition	recognition	NOUN
fnp-4682	482	9	,	,	PUNCT
fnp-4682	482	10	and	and	CCONJ
fnp-4682	482	11	inhibition	inhibition	NOUN
fnp-4682	482	12	by	by	ADP
fnp-4682	482	13	small	small	ADJ
fnp-4682	482	14	molecules	molecule	NOUN
fnp-4682	482	15	.	.	PUNCT
fnp-4682	483	1	mol	mol	ADP
fnp-4682	483	2	cell	cell	NOUN
fnp-4682	483	3	82	82	NUM
fnp-4682	483	4	,	,	PUNCT
fnp-4682	483	5	1643	1643	NUM
fnp-4682	483	6	-	-	SYM
fnp-4682	483	7	1659	1659	NUM
fnp-4682	483	8	.	.	PUNCT
fnp-4682	484	1	https://doi.org/10.1016/j.molcel.2022.03.007	https://doi.org/10.1016/j.molcel.2022.03.007	PROPN
fnp-4682	484	2	simon	simon	PROPN
fnp-4682	484	3	,	,	PUNCT
fnp-4682	484	4	d.j	d.j	PROPN
fnp-4682	484	5	.	.	PROPN
fnp-4682	484	6	,	,	PUNCT
fnp-4682	484	7	and	and	CCONJ
fnp-4682	484	8	watkins	watkins	PROPN
fnp-4682	484	9	,	,	PUNCT
fnp-4682	484	10	t.a	t.a	PROPN
fnp-4682	484	11	.	.	PROPN
fnp-4682	484	12	(	(	PUNCT
fnp-4682	484	13	2018	2018	NUM
fnp-4682	484	14	)	)	PUNCT
fnp-4682	484	15	.	.	PUNCT
fnp-4682	485	1	therapeutic	therapeutic	ADJ
fnp-4682	485	2	opportunities	opportunity	NOUN
fnp-4682	485	3	and	and	CCONJ
fnp-4682	485	4	pitfalls	pitfall	NOUN
fnp-4682	485	5	in	in	ADP
fnp-4682	485	6	the	the	DET
fnp-4682	485	7	treatment	treatment	NOUN
fnp-4682	485	8	of	of	ADP
fnp-4682	485	9	axon	axon	NOUN
fnp-4682	485	10	degeneration	degeneration	NOUN
fnp-4682	485	11	.	.	PUNCT
fnp-4682	486	1	curr	curr	PROPN
fnp-4682	486	2	opin	opin	PROPN
fnp-4682	486	3	neurol	neurol	NOUN
fnp-4682	486	4	31	31	NUM
fnp-4682	486	5	,	,	PUNCT
fnp-4682	486	6	693	693	NUM
fnp-4682	486	7	-	-	SYM
fnp-4682	486	8	701	701	NUM
fnp-4682	486	9	.	.	PUNCT
fnp-4682	487	1	https://doi.org/10.1097/wco.0000000000000621	https://doi.org/10.1097/wco.0000000000000621	NOUN
fnp-4682	487	2	stevanovski	stevanovski	PROPN
fnp-4682	487	3	,	,	PUNCT
fnp-4682	487	4	i.	i.	PROPN
fnp-4682	487	5	,	,	PUNCT
fnp-4682	487	6	chintalaphani	chintalaphani	PROPN
fnp-4682	487	7	,	,	PUNCT
fnp-4682	487	8	s.r	s.r	PROPN
fnp-4682	487	9	.	.	PROPN
fnp-4682	487	10	,	,	PUNCT
fnp-4682	487	11	gamaarachchi	gamaarachchi	PROPN
fnp-4682	487	12	,	,	PUNCT
fnp-4682	487	13	h.	h.	PROPN
fnp-4682	487	14	,	,	PUNCT
fnp-4682	487	15	ferguson	ferguson	PROPN
fnp-4682	487	16	,	,	PUNCT
fnp-4682	487	17	j.m	j.m	PROPN
fnp-4682	487	18	.	.	PROPN
fnp-4682	487	19	,	,	PUNCT
fnp-4682	487	20	pineda	pineda	PROPN
fnp-4682	487	21	,	,	PUNCT
fnp-4682	487	22	s.s	s.s	PROPN
fnp-4682	487	23	.	.	PROPN
fnp-4682	487	24	,	,	PUNCT
fnp-4682	487	25	scriba	scriba	PROPN
fnp-4682	487	26	,	,	PUNCT
fnp-4682	487	27	c.k	c.k	PROPN
fnp-4682	487	28	.	.	PROPN
fnp-4682	487	29	,	,	PUNCT
fnp-4682	487	30	tchan	tchan	NOUN
fnp-4682	487	31	,	,	PUNCT
fnp-4682	487	32	m.	m.	NOUN
fnp-4682	487	33	,	,	PUNCT
fnp-4682	487	34	fung	fung	PROPN
fnp-4682	487	35	,	,	PUNCT
fnp-4682	487	36	v.	v.	PROPN
fnp-4682	487	37	,	,	PUNCT
fnp-4682	487	38	ng	ng	PROPN
fnp-4682	487	39	,	,	PUNCT
fnp-4682	487	40	k.	k.	PROPN
fnp-4682	487	41	,	,	PUNCT
fnp-4682	487	42	cortese	cortese	PROPN
fnp-4682	487	43	,	,	PUNCT
fnp-4682	487	44	a.	a.	PROPN
fnp-4682	487	45	,	,	PUNCT
fnp-4682	487	46	et	et	PROPN
fnp-4682	487	47	al	al	PROPN
fnp-4682	487	48	.	.	PROPN
fnp-4682	487	49	(	(	PUNCT
fnp-4682	487	50	2022	2022	NUM
fnp-4682	487	51	)	)	PUNCT
fnp-4682	487	52	.	.	PUNCT
fnp-4682	488	1	comprehensive	comprehensive	ADJ
fnp-4682	488	2	genetic	genetic	ADJ
fnp-4682	488	3	diagnosis	diagnosis	NOUN
fnp-4682	488	4	of	of	ADP
fnp-4682	488	5	tandem	tandem	NOUN
fnp-4682	488	6	repeat	repeat	NOUN
fnp-4682	488	7	expansion	expansion	NOUN
fnp-4682	488	8	disorders	disorder	NOUN
fnp-4682	488	9	with	with	ADP
fnp-4682	488	10	programmable	programmable	ADJ
fnp-4682	488	11	targeted	target	VERB
fnp-4682	488	12	nanopore	nanopore	ADV
fnp-4682	488	13	sequencing	sequencing	NOUN
fnp-4682	488	14	.	.	PUNCT
fnp-4682	489	1	sci	sci	PROPN
fnp-4682	489	2	adv	adv	PROPN
fnp-4682	489	3	8	8	NUM
fnp-4682	489	4	,	,	PUNCT
fnp-4682	489	5	eabm5386	eabm5386	NUM
fnp-4682	489	6	.	.	PUNCT
fnp-4682	490	1	https://doi.org/10.1126/sciadv.abm5386	https://doi.org/10.1126/sciadv.abm5386	NOUN
fnp-4682	490	2	vallat	vallat	NOUN
fnp-4682	490	3	,	,	PUNCT
fnp-4682	490	4	j.m	j.m	PROPN
fnp-4682	490	5	.	.	PROPN
fnp-4682	490	6	,	,	PUNCT
fnp-4682	490	7	magy	magy	PROPN
fnp-4682	490	8	,	,	PUNCT
fnp-4682	490	9	l.	l.	PROPN
fnp-4682	490	10	,	,	PUNCT
fnp-4682	490	11	corcia	corcia	PROPN
fnp-4682	490	12	,	,	PUNCT
fnp-4682	490	13	p.	p.	NOUN
fnp-4682	490	14	,	,	PUNCT
fnp-4682	490	15	boulesteix	boulesteix	NOUN
fnp-4682	490	16	,	,	PUNCT
fnp-4682	490	17	j.m	j.m	PROPN
fnp-4682	490	18	.	.	PROPN
fnp-4682	490	19	,	,	PUNCT
fnp-4682	490	20	uncini	uncini	PROPN
fnp-4682	490	21	,	,	PUNCT
fnp-4682	490	22	a.	a.	NOUN
fnp-4682	490	23	,	,	PUNCT
fnp-4682	490	24	and	and	CCONJ
fnp-4682	490	25	mathis	mathis	PROPN
fnp-4682	490	26	,	,	PUNCT
fnp-4682	490	27	s.	s.	PROPN
fnp-4682	490	28	(	(	PUNCT
fnp-4682	490	29	2020	2020	NUM
fnp-4682	490	30	)	)	PUNCT
fnp-4682	490	31	.	.	PUNCT
fnp-4682	491	1	ultrastructural	ultrastructural	ADJ
fnp-4682	491	2	lesions	lesion	NOUN
fnp-4682	491	3	of	of	ADP
fnp-4682	491	4	nodo	nodo	NOUN
fnp-4682	491	5	-	-	PUNCT
fnp-4682	491	6	paranodopathies	paranodopathie	NOUN
fnp-4682	491	7	in	in	ADP
fnp-4682	491	8	peripheral	peripheral	ADJ
fnp-4682	491	9	neuropathies	neuropathy	NOUN
fnp-4682	491	10	.	.	PUNCT
fnp-4682	492	1	j	j	PROPN
fnp-4682	492	2	neuropathol	neuropathol	PROPN
fnp-4682	492	3	exp	exp	PROPN
fnp-4682	492	4	neurol	neurol	PROPN
fnp-4682	492	5	79	79	NUM
fnp-4682	492	6	,	,	PUNCT
fnp-4682	492	7	247	247	NUM
fnp-4682	492	8	-	-	SYM
fnp-4682	492	9	255	255	NUM
fnp-4682	492	10	.	.	PUNCT
fnp-4682	493	1	https://doi.org/10.1093/jnen/nlz134	https://doi.org/10.1093/jnen/nlz134	PROPN
fnp-4682	493	2	volpatti	volpatti	PROPN
fnp-4682	493	3	,	,	PUNCT
fnp-4682	493	4	j.r	j.r	PROPN
fnp-4682	493	5	.	.	PROPN
fnp-4682	493	6	,	,	PUNCT
fnp-4682	493	7	ghahramani	ghahramani	NOUN
fnp-4682	493	8	-	-	PUNCT
fnp-4682	493	9	seno	seno	PROPN
fnp-4682	493	10	,	,	PUNCT
fnp-4682	493	11	m.m	m.m	PROPN
fnp-4682	493	12	.	.	PROPN
fnp-4682	493	13	,	,	PUNCT
fnp-4682	493	14	mansat	mansat	PROPN
fnp-4682	493	15	,	,	PUNCT
fnp-4682	493	16	m.	m.	NOUN
fnp-4682	493	17	,	,	PUNCT
fnp-4682	493	18	sabha	sabha	NOUN
fnp-4682	493	19	,	,	PUNCT
fnp-4682	493	20	n.	n.	NOUN
fnp-4682	493	21	,	,	PUNCT
fnp-4682	493	22	sarikaya	sarikaya	PROPN
fnp-4682	493	23	,	,	PUNCT
fnp-4682	493	24	e.	e.	PROPN
fnp-4682	493	25	,	,	PUNCT
fnp-4682	493	26	goodman	goodman	PROPN
fnp-4682	493	27	,	,	PUNCT
fnp-4682	493	28	s.j	s.j	PROPN
fnp-4682	493	29	.	.	PROPN
fnp-4682	493	30	,	,	PUNCT
fnp-4682	493	31	chater	chater	NOUN
fnp-4682	493	32	-	-	PUNCT
fnp-4682	493	33	diehl	diehl	PROPN
fnp-4682	493	34	,	,	PUNCT
fnp-4682	493	35	e.	e.	PROPN
fnp-4682	493	36	,	,	PUNCT
fnp-4682	493	37	celik	celik	VERB
fnp-4682	493	38	,	,	PUNCT
fnp-4682	493	39	a.	a.	NOUN
fnp-4682	493	40	,	,	PUNCT
fnp-4682	493	41	pannia	pannia	PROPN
fnp-4682	493	42	,	,	PUNCT
fnp-4682	493	43	e.	e.	PROPN
fnp-4682	493	44	,	,	PUNCT
fnp-4682	493	45	froment	froment	PROPN
fnp-4682	493	46	,	,	PUNCT
fnp-4682	493	47	c.	c.	PROPN
fnp-4682	493	48	,	,	PUNCT
fnp-4682	493	49	et	et	PROPN
fnp-4682	493	50	al	al	PROPN
fnp-4682	493	51	.	.	PROPN
fnp-4682	494	1	(	(	PUNCT
fnp-4682	494	2	2022	2022	NUM
fnp-4682	494	3	)	)	PUNCT
fnp-4682	494	4	.	.	PUNCT
fnp-4682	495	1	x	x	X
fnp-4682	495	2	-	-	VERB
fnp-4682	495	3	linked	link	VERB
fnp-4682	495	4	myotubular	myotubular	ADJ
fnp-4682	495	5	myopathy	myopathy	NOUN
fnp-4682	495	6	is	be	AUX
fnp-4682	495	7	associated	associate	VERB
fnp-4682	495	8	with	with	ADP
fnp-4682	495	9	epigenetic	epigenetic	ADJ
fnp-4682	495	10	alterations	alteration	NOUN
fnp-4682	495	11	and	and	CCONJ
fnp-4682	495	12	is	be	AUX
fnp-4682	495	13	ameliorated	ameliorate	VERB
fnp-4682	495	14	by	by	ADP
fnp-4682	495	15	hdac	hdac	NOUN
fnp-4682	495	16	inhibition	inhibition	NOUN
fnp-4682	495	17	.	.	PUNCT
fnp-4682	496	1	acta	acta	PROPN
fnp-4682	496	2	neuropathol	neuropathol	PROPN
fnp-4682	496	3	144	144	NUM
fnp-4682	496	4	,	,	PUNCT
fnp-4682	496	5	537	537	NUM
fnp-4682	496	6	-	-	SYM
fnp-4682	496	7	563	563	NUM
fnp-4682	496	8	.	.	PUNCT
fnp-4682	497	1	https://doi.org/10.1007/s00401-022-02468-7	https://doi.org/10.1007/s00401-022-02468-7	NUM
fnp-4682	498	1	wang	wang	PROPN
fnp-4682	498	2	,	,	PUNCT
fnp-4682	498	3	x.	x.	PROPN
fnp-4682	498	4	,	,	PUNCT
fnp-4682	498	5	jia	jia	PROPN
fnp-4682	498	6	,	,	PUNCT
fnp-4682	498	7	y.	y.	PROPN
fnp-4682	498	8	,	,	PUNCT
fnp-4682	498	9	zhao	zhao	PROPN
fnp-4682	498	10	,	,	PUNCT
fnp-4682	498	11	j.	j.	PROPN
fnp-4682	498	12	,	,	PUNCT
fnp-4682	498	13	lesner	lesner	PROPN
fnp-4682	498	14	,	,	PUNCT
fnp-4682	498	15	n.p	n.p	PROPN
fnp-4682	498	16	.	.	PROPN
fnp-4682	498	17	,	,	PUNCT
fnp-4682	498	18	menezes	menezes	PROPN
fnp-4682	498	19	,	,	PUNCT
fnp-4682	498	20	c.j	c.j	PROPN
fnp-4682	498	21	.	.	PROPN
fnp-4682	498	22	,	,	PUNCT
fnp-4682	498	23	shelton	shelton	PROPN
fnp-4682	498	24	,	,	PUNCT
fnp-4682	498	25	s.d	s.d	PROPN
fnp-4682	498	26	.	.	PROPN
fnp-4682	498	27	,	,	PUNCT
fnp-4682	498	28	venigalla	venigalla	PROPN
fnp-4682	498	29	,	,	PUNCT
fnp-4682	498	30	s.s.k	s.s.k	NOUN
fnp-4682	498	31	.	.	PROPN
fnp-4682	498	32	,	,	PUNCT
fnp-4682	498	33	xu	xu	PROPN
fnp-4682	498	34	,	,	PUNCT
fnp-4682	498	35	j.	j.	PROPN
fnp-4682	498	36	,	,	PUNCT
fnp-4682	498	37	cai	cai	PROPN
fnp-4682	498	38	,	,	PUNCT
fnp-4682	498	39	c.	c.	PROPN
fnp-4682	498	40	,	,	PUNCT
fnp-4682	498	41	and	and	CCONJ
fnp-4682	498	42	mishra	mishra	PROPN
fnp-4682	498	43	,	,	PUNCT
fnp-4682	498	44	p.	p.	NOUN
fnp-4682	498	45	(	(	PUNCT
fnp-4682	498	46	2022	2022	NUM
fnp-4682	498	47	)	)	PUNCT
fnp-4682	498	48	.	.	PUNCT
fnp-4682	499	1	a	a	DET
fnp-4682	499	2	mitofusin	mitofusin	NOUN
fnp-4682	499	3	2	2	NUM
fnp-4682	499	4	/	/	SYM
fnp-4682	499	5	hif1alpha	hif1alpha	PROPN
fnp-4682	499	6	axis	axis	NOUN
fnp-4682	499	7	sets	set	VERB
fnp-4682	499	8	a	a	DET
fnp-4682	499	9	maturation	maturation	NOUN
fnp-4682	499	10	checkpoint	checkpoint	NOUN
fnp-4682	499	11	in	in	ADP
fnp-4682	499	12	regenerating	regenerate	VERB
fnp-4682	499	13	skeletal	skeletal	ADJ
fnp-4682	499	14	muscle	muscle	NOUN
fnp-4682	499	15	.	.	PUNCT
fnp-4682	500	1	j	j	PROPN
fnp-4682	500	2	clin	clin	PROPN
fnp-4682	500	3	invest	invest	VERB
fnp-4682	500	4	132	132	NUM
fnp-4682	500	5	,	,	PUNCT
fnp-4682	500	6	e161638	e161638	PROPN
fnp-4682	500	7	.	.	PUNCT
fnp-4682	501	1	https://doi.org/10.1172/jci161638	https://doi.org/10.1172/jci161638	PROPN
fnp-4682	501	2	weihl	weihl	PROPN
fnp-4682	501	3	,	,	PUNCT
fnp-4682	501	4	c.c	c.c	PROPN
fnp-4682	501	5	.	.	PROPN
fnp-4682	501	6	,	,	PUNCT
fnp-4682	501	7	topf	topf	PROPN
fnp-4682	501	8	,	,	PUNCT
fnp-4682	501	9	a.	a.	NOUN
fnp-4682	501	10	,	,	PUNCT
fnp-4682	501	11	bengoechea	bengoechea	PROPN
fnp-4682	501	12	,	,	PUNCT
fnp-4682	501	13	r.	r.	PROPN
fnp-4682	501	14	,	,	PUNCT
fnp-4682	501	15	duff	duff	PROPN
fnp-4682	501	16	,	,	PUNCT
fnp-4682	501	17	j.	j.	PROPN
fnp-4682	501	18	,	,	PUNCT
fnp-4682	501	19	charlton	charlton	PROPN
fnp-4682	501	20	,	,	PUNCT
fnp-4682	501	21	r.	r.	PROPN
fnp-4682	501	22	,	,	PUNCT
fnp-4682	501	23	garcia	garcia	PROPN
fnp-4682	501	24	,	,	PUNCT
fnp-4682	501	25	s.k	s.k	PROPN
fnp-4682	501	26	.	.	PROPN
fnp-4682	501	27	,	,	PUNCT
fnp-4682	501	28	dominguez	dominguez	PROPN
fnp-4682	501	29	-	-	PUNCT
fnp-4682	501	30	gonzalez	gonzalez	PROPN
fnp-4682	501	31	,	,	PUNCT
fnp-4682	501	32	c.	c.	PROPN
fnp-4682	501	33	,	,	PUNCT
fnp-4682	501	34	alsaman	alsaman	PROPN
fnp-4682	501	35	,	,	PUNCT
fnp-4682	501	36	a.	a.	NOUN
fnp-4682	501	37	,	,	PUNCT
fnp-4682	501	38	hernandez	hernandez	PROPN
fnp-4682	501	39	-	-	PUNCT
fnp-4682	501	40	lain	lain	PROPN
fnp-4682	501	41	,	,	PUNCT
fnp-4682	501	42	a.	a.	NOUN
fnp-4682	501	43	,	,	PUNCT
fnp-4682	501	44	franco	franco	PROPN
fnp-4682	501	45	,	,	PUNCT
fnp-4682	501	46	l.v	l.v	PROPN
fnp-4682	501	47	.	.	PROPN
fnp-4682	501	48	,	,	PUNCT
fnp-4682	501	49	et	et	PROPN
fnp-4682	501	50	al	al	PROPN
fnp-4682	501	51	.	.	PROPN
fnp-4682	501	52	(	(	PUNCT
fnp-4682	501	53	2023	2023	NUM
fnp-4682	501	54	)	)	PUNCT
fnp-4682	501	55	.	.	PUNCT
fnp-4682	502	1	loss	loss	NOUN
fnp-4682	502	2	of	of	ADP
fnp-4682	502	3	function	function	NOUN
fnp-4682	502	4	variants	variant	NOUN
fnp-4682	502	5	in	in	ADP
fnp-4682	502	6	dnajb4	dnajb4	PROPN
fnp-4682	502	7	cause	cause	VERB
fnp-4682	502	8	a	a	DET
fnp-4682	502	9	myopathy	myopathy	NOUN
fnp-4682	502	10	with	with	ADP
fnp-4682	502	11	early	early	ADJ
fnp-4682	502	12	respiratory	respiratory	ADJ
fnp-4682	502	13	failure	failure	NOUN
fnp-4682	502	14	.	.	PUNCT
fnp-4682	503	1	acta	acta	PROPN
fnp-4682	503	2	neuropathol	neuropathol	PROPN
fnp-4682	503	3	145	145	NUM
fnp-4682	503	4	,	,	PUNCT
fnp-4682	503	5	127	127	NUM
fnp-4682	503	6	-	-	SYM
fnp-4682	503	7	143	143	NUM
fnp-4682	503	8	.	.	PUNCT
fnp-4682	504	1	https://doi.org/10.1007/s00401-022-02510-8	https://doi.org/10.1007/s00401-022-02510-8	NUM
fnp-4682	504	2	winkler	winkler	NOUN
fnp-4682	504	3	,	,	PUNCT
fnp-4682	504	4	m.	m.	NOUN
fnp-4682	504	5	,	,	PUNCT
fnp-4682	504	6	von	von	PROPN
fnp-4682	504	7	landenberg	landenberg	PROPN
fnp-4682	504	8	,	,	PUNCT
fnp-4682	504	9	c.	c.	PROPN
fnp-4682	504	10	,	,	PUNCT
fnp-4682	504	11	kappes	kappe	NOUN
fnp-4682	504	12	-	-	PUNCT
fnp-4682	504	13	horn	horn	NOUN
fnp-4682	504	14	,	,	PUNCT
fnp-4682	504	15	k.	k.	PROPN
fnp-4682	504	16	,	,	PUNCT
fnp-4682	504	17	neudecker	neudecker	PROPN
fnp-4682	504	18	,	,	PUNCT
fnp-4682	504	19	s.	s.	PROPN
fnp-4682	504	20	,	,	PUNCT
fnp-4682	504	21	kornblum	kornblum	PROPN
fnp-4682	504	22	,	,	PUNCT
fnp-4682	504	23	c.	c.	NOUN
fnp-4682	504	24	,	,	PUNCT
fnp-4682	504	25	and	and	CCONJ
fnp-4682	504	26	reimann	reimann	PROPN
fnp-4682	504	27	,	,	PUNCT
fnp-4682	504	28	j.	j.	PROPN
fnp-4682	504	29	(	(	PUNCT
fnp-4682	504	30	2021	2021	NUM
fnp-4682	504	31	)	)	PUNCT
fnp-4682	504	32	.	.	PUNCT
fnp-4682	505	1	diagnosis	diagnosis	NOUN
fnp-4682	505	2	and	and	CCONJ
fnp-4682	505	3	clinical	clinical	ADJ
fnp-4682	505	4	development	development	NOUN
fnp-4682	505	5	of	of	ADP
fnp-4682	505	6	sporadic	sporadic	ADJ
fnp-4682	505	7	inclusion	inclusion	NOUN
fnp-4682	505	8	body	body	NOUN
fnp-4682	505	9	myositis	myositis	NOUN
fnp-4682	505	10	and	and	CCONJ
fnp-4682	505	11	polymyositis	polymyositis	PROPN
fnp-4682	505	12	with	with	ADP
fnp-4682	505	13	mitochondrial	mitochondrial	ADJ
fnp-4682	505	14	pathology	pathology	NOUN
fnp-4682	505	15	:	:	PUNCT
fnp-4682	505	16	a	a	DET
fnp-4682	505	17	single	single	ADJ
fnp-4682	505	18	-	-	PUNCT
fnp-4682	505	19	center	center	NOUN
fnp-4682	505	20	retrospective	retrospective	ADJ
fnp-4682	505	21	analysis	analysis	NOUN
fnp-4682	505	22	.	.	PUNCT
fnp-4682	506	1	j	j	PROPN
fnp-4682	506	2	neuropathol	neuropathol	PROPN
fnp-4682	506	3	exp	exp	PROPN
fnp-4682	506	4	neurol	neurol	PROPN
fnp-4682	506	5	80	80	NUM
fnp-4682	506	6	,	,	PUNCT
fnp-4682	506	7	1060	1060	NUM
fnp-4682	506	8	-	-	SYM
fnp-4682	506	9	1067	1067	NUM
fnp-4682	506	10	.	.	PUNCT
fnp-4682	507	1	https://doi.org/10.1093/jnen/nlab101	https://doi.org/10.1093/jnen/nlab101	NOUN
fnp-4682	507	2	copyright	copyright	NOUN
fnp-4682	507	3	:	:	PUNCT
fnp-4682	507	4	©	©	PROPN
fnp-4682	507	5	2023	2023	NUM
fnp-4682	507	6	the	the	DET
fnp-4682	507	7	author(s	author(s	NOUN
fnp-4682	507	8	)	)	PUNCT
fnp-4682	507	9	.	.	PUNCT
fnp-4682	508	1	this	this	PRON
fnp-4682	508	2	is	be	AUX
fnp-4682	508	3	an	an	DET
fnp-4682	508	4	open	open	ADJ
fnp-4682	508	5	access	access	NOUN
fnp-4682	508	6	article	article	NOUN
fnp-4682	508	7	distributed	distribute	VERB
fnp-4682	508	8	under	under	ADP
fnp-4682	508	9	the	the	DET
fnp-4682	508	10	terms	term	NOUN
fnp-4682	508	11	of	of	ADP
fnp-4682	508	12	the	the	DET
fnp-4682	508	13	creative	creative	ADJ
fnp-4682	508	14	commons	common	NOUN
fnp-4682	508	15	attribution	attribution	NOUN
fnp-4682	508	16	4.0	4.0	NUM
fnp-4682	508	17	international	international	ADJ
fnp-4682	508	18	license	license	NOUN
fnp-4682	508	19	(	(	PUNCT
fnp-4682	508	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-4682	508	21	)	)	PUNCT
fnp-4682	508	22	,	,	PUNCT
fnp-4682	508	23	which	which	PRON
fnp-4682	508	24	permits	permit	VERB
fnp-4682	508	25	unrestricted	unrestricted	ADJ
fnp-4682	508	26	use	use	NOUN
fnp-4682	508	27	,	,	PUNCT
fnp-4682	508	28	distribution	distribution	NOUN
fnp-4682	508	29	,	,	PUNCT
fnp-4682	508	30	and	and	CCONJ
fnp-4682	508	31	reproduction	reproduction	NOUN
fnp-4682	508	32	in	in	ADP
fnp-4682	508	33	any	any	DET
fnp-4682	508	34	medium	medium	NOUN
fnp-4682	508	35	,	,	PUNCT
fnp-4682	508	36	provided	provide	VERB
fnp-4682	508	37	the	the	DET
fnp-4682	508	38	original	original	ADJ
fnp-4682	508	39	author	author	NOUN
fnp-4682	508	40	and	and	CCONJ
fnp-4682	508	41	source	source	NOUN
fnp-4682	508	42	are	be	AUX
fnp-4682	508	43	credited	credit	VERB
fnp-4682	508	44	,	,	PUNCT
fnp-4682	508	45	a	a	DET
fnp-4682	508	46	link	link	NOUN
fnp-4682	508	47	to	to	ADP
fnp-4682	508	48	the	the	DET
fnp-4682	508	49	creative	creative	ADJ
fnp-4682	508	50	commons	common	NOUN
fnp-4682	508	51	license	license	NOUN
fnp-4682	508	52	is	be	AUX
fnp-4682	508	53	provided	provide	VERB
fnp-4682	508	54	,	,	PUNCT
fnp-4682	508	55	and	and	CCONJ
fnp-4682	508	56	any	any	DET
fnp-4682	508	57	changes	change	NOUN
fnp-4682	508	58	are	be	AUX
fnp-4682	508	59	indicated	indicate	VERB
fnp-4682	508	60	.	.	PUNCT
fnp-4682	509	1	the	the	DET
fnp-4682	509	2	creative	creative	ADJ
fnp-4682	509	3	commons	common	NOUN
fnp-4682	509	4	public	public	ADJ
fnp-4682	509	5	domain	domain	NOUN
fnp-4682	509	6	dedication	dedication	NOUN
fnp-4682	509	7	waiver	waiver	NOUN
fnp-4682	509	8	(	(	PUNCT
fnp-4682	509	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-4682	509	10	)	)	PUNCT
fnp-4682	509	11	applies	apply	VERB
fnp-4682	509	12	to	to	ADP
fnp-4682	509	13	the	the	DET
fnp-4682	509	14	data	datum	NOUN
fnp-4682	509	15	made	make	VERB
fnp-4682	509	16	available	available	ADJ
fnp-4682	509	17	in	in	ADP
fnp-4682	509	18	this	this	DET
fnp-4682	509	19	article	article	NOUN
fnp-4682	509	20	,	,	PUNCT
fnp-4682	509	21	unless	unless	SCONJ
fnp-4682	509	22	otherwise	otherwise	ADV
fnp-4682	509	23	stated	state	VERB
fnp-4682	509	24	.	.	PUNCT