id	sid	tid	token	lemma	pos
fnp-5156	1	1	reference	reference	NOUN
fnp-5156	1	2	on	on	ADP
fnp-5156	1	3	copy	copy	NOUN
fnp-5156	1	4	number	number	NOUN
fnp-5156	1	5	variations	variation	NOUN
fnp-5156	1	6	in	in	ADP
fnp-5156	1	7	pleomorphic	pleomorphic	ADJ
fnp-5156	1	8	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	1	9	:	:	PUNCT
fnp-5156	1	10	implications	implication	NOUN
fnp-5156	1	11	for	for	ADP
fnp-5156	1	12	diagnostic	diagnostic	ADJ
fnp-5156	1	13	approach	approach	NOUN
fnp-5156	1	14	feel	feel	VERB
fnp-5156	1	15	free	free	ADJ
fnp-5156	1	16	to	to	PART
fnp-5156	1	17	add	add	VERB
fnp-5156	1	18	comments	comment	NOUN
fnp-5156	1	19	by	by	ADP
fnp-5156	1	20	clicking	click	VERB
fnp-5156	1	21	these	these	DET
fnp-5156	1	22	icons	icon	NOUN
fnp-5156	1	23	on	on	ADP
fnp-5156	1	24	the	the	DET
fnp-5156	1	25	sidebar	sidebar	NOUN
fnp-5156	1	26	free	free	ADJ
fnp-5156	1	27	neuropathology	neuropathology	NOUN
fnp-5156	1	28	4:19	4:19	NUM
fnp-5156	1	29	(	(	PUNCT
fnp-5156	1	30	2023	2023	NUM
fnp-5156	1	31	)	)	PUNCT
fnp-5156	1	32	original	original	ADJ
fnp-5156	1	33	paper	paper	NOUN
fnp-5156	1	34	reference	reference	NOUN
fnp-5156	1	35	on	on	ADP
fnp-5156	1	36	copy	copy	NOUN
fnp-5156	1	37	number	number	NOUN
fnp-5156	1	38	variations	variation	NOUN
fnp-5156	1	39	in	in	ADP
fnp-5156	1	40	pleomorphic	pleomorphic	ADJ
fnp-5156	1	41	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	1	42	:	:	PUNCT
fnp-5156	1	43	implications	implication	NOUN
fnp-5156	1	44	for	for	ADP
fnp-5156	1	45	diagnostic	diagnostic	ADJ
fnp-5156	1	46	approach	approach	NOUN
fnp-5156	1	47	david	david	PROPN
fnp-5156	1	48	e.	e.	PROPN
fnp-5156	1	49	reuss1,2	reuss1,2	PROPN
fnp-5156	1	50	,	,	PUNCT
fnp-5156	1	51	daniel	daniel	PROPN
fnp-5156	1	52	schrimpf1,2	schrimpf1,2	PROPN
fnp-5156	1	53	,	,	PUNCT
fnp-5156	1	54	damian	damian	PROPN
fnp-5156	1	55	stichel1,2	stichel1,2	PROPN
fnp-5156	1	56	,	,	PUNCT
fnp-5156	1	57	azadeh	azadeh	PROPN
fnp-5156	1	58	ebrahimi3	ebrahimi3	PROPN
fnp-5156	1	59	,	,	PUNCT
fnp-5156	1	60	chris	chris	PROPN
fnp-5156	1	61	dampier4	dampier4	PROPN
fnp-5156	1	62	,	,	PUNCT
fnp-5156	1	63	kenneth	kenneth	PROPN
fnp-5156	1	64	aldape4	aldape4	PROPN
fnp-5156	1	65	,	,	PUNCT
fnp-5156	1	66	matija	matija	NOUN
fnp-5156	1	67	snuderl5	snuderl5	PROPN
fnp-5156	1	68	,	,	PUNCT
fnp-5156	1	69	david	david	PROPN
fnp-5156	1	70	capper6	capper6	PROPN
fnp-5156	1	71	,	,	PUNCT
fnp-5156	1	72	martin	martin	PROPN
fnp-5156	1	73	sill7,8	sill7,8	PROPN
fnp-5156	1	74	,	,	PUNCT
fnp-5156	1	75	david	david	PROPN
fnp-5156	1	76	t.	t.	PROPN
fnp-5156	1	77	w.	w.	PROPN
fnp-5156	1	78	jones8,9	jones8,9	PROPN
fnp-5156	1	79	,	,	PUNCT
fnp-5156	1	80	stefan	stefan	PROPN
fnp-5156	1	81	m.	m.	PROPN
fnp-5156	1	82	pfister2,8,10	pfister2,8,10	PROPN
fnp-5156	1	83	,	,	PUNCT
fnp-5156	1	84	felix	felix	PROPN
fnp-5156	1	85	sahm1,2,8	sahm1,2,8	PROPN
fnp-5156	1	86	,	,	PUNCT
fnp-5156	1	87	andreas	andreas	PROPN
fnp-5156	1	88	von	von	PROPN
fnp-5156	1	89	deimling1,2,8	deimling1,2,8	PROPN
fnp-5156	1	90	department	department	PROPN
fnp-5156	1	91	of	of	ADP
fnp-5156	1	92	neuropathology	neuropathology	PROPN
fnp-5156	1	93	,	,	PUNCT
fnp-5156	1	94	institute	institute	PROPN
fnp-5156	1	95	of	of	ADP
fnp-5156	1	96	pathology	pathology	PROPN
fnp-5156	1	97	,	,	PUNCT
fnp-5156	1	98	university	university	PROPN
fnp-5156	1	99	of	of	ADP
fnp-5156	1	100	heidelberg	heidelberg	PROPN
fnp-5156	1	101	,	,	PUNCT
fnp-5156	1	102	heidelberg	heidelberg	PROPN
fnp-5156	1	103	,	,	PUNCT
fnp-5156	1	104	germany	germany	PROPN
fnp-5156	1	105	clinical	clinical	ADJ
fnp-5156	1	106	cooperation	cooperation	NOUN
fnp-5156	1	107	unit	unit	NOUN
fnp-5156	1	108	neuropathology	neuropathology	NOUN
fnp-5156	1	109	,	,	PUNCT
fnp-5156	1	110	german	german	ADJ
fnp-5156	1	111	cancer	cancer	NOUN
fnp-5156	1	112	consortium	consortium	NOUN
fnp-5156	1	113	(	(	PUNCT
fnp-5156	1	114	dktk	dktk	NOUN
fnp-5156	1	115	)	)	PUNCT
fnp-5156	1	116	,	,	PUNCT
fnp-5156	1	117	german	german	ADJ
fnp-5156	1	118	cancer	cancer	NOUN
fnp-5156	1	119	research	research	NOUN
fnp-5156	1	120	center	center	NOUN
fnp-5156	1	121	(	(	PUNCT
fnp-5156	1	122	dkfz	dkfz	PROPN
fnp-5156	1	123	)	)	PUNCT
fnp-5156	1	124	,	,	PUNCT
fnp-5156	1	125	heidelberg	heidelberg	PROPN
fnp-5156	1	126	,	,	PUNCT
fnp-5156	1	127	germany	germany	PROPN
fnp-5156	1	128	department	department	PROPN
fnp-5156	1	129	of	of	ADP
fnp-5156	1	130	neuropathology	neuropathology	NOUN
fnp-5156	1	131	,	,	PUNCT
fnp-5156	1	132	dgnn	dgnn	NOUN
fnp-5156	1	133	brain	brain	NOUN
fnp-5156	1	134	tumor	tumor	PROPN
fnp-5156	1	135	reference	reference	NOUN
fnp-5156	1	136	center	center	NOUN
fnp-5156	1	137	,	,	PUNCT
fnp-5156	1	138	university	university	NOUN
fnp-5156	1	139	of	of	ADP
fnp-5156	1	140	bonn	bonn	PROPN
fnp-5156	1	141	,	,	PUNCT
fnp-5156	1	142	bonn	bonn	PROPN
fnp-5156	1	143	,	,	PUNCT
fnp-5156	1	144	germany	germany	PROPN
fnp-5156	1	145	laboratory	laboratory	PROPN
fnp-5156	1	146	of	of	ADP
fnp-5156	1	147	pathology	pathology	PROPN
fnp-5156	1	148	,	,	PUNCT
fnp-5156	1	149	national	national	PROPN
fnp-5156	1	150	cancer	cancer	PROPN
fnp-5156	1	151	institute	institute	PROPN
fnp-5156	1	152	,	,	PUNCT
fnp-5156	1	153	centre	centre	NOUN
fnp-5156	1	154	for	for	ADP
fnp-5156	1	155	cancer	cancer	NOUN
fnp-5156	1	156	research	research	NOUN
fnp-5156	1	157	,	,	PUNCT
fnp-5156	1	158	bethesda	bethesda	PROPN
fnp-5156	1	159	,	,	PUNCT
fnp-5156	1	160	md	md	PROPN
fnp-5156	1	161	,	,	PUNCT
fnp-5156	1	162	usa	usa	PROPN
fnp-5156	1	163	department	department	PROPN
fnp-5156	1	164	of	of	ADP
fnp-5156	1	165	pathology	pathology	PROPN
fnp-5156	1	166	,	,	PUNCT
fnp-5156	1	167	new	new	PROPN
fnp-5156	1	168	york	york	PROPN
fnp-5156	1	169	university	university	PROPN
fnp-5156	1	170	langone	langone	NOUN
fnp-5156	1	171	health	health	NOUN
fnp-5156	1	172	and	and	CCONJ
fnp-5156	1	173	school	school	NOUN
fnp-5156	1	174	of	of	ADP
fnp-5156	1	175	medicine	medicine	NOUN
fnp-5156	1	176	,	,	PUNCT
fnp-5156	1	177	new	new	PROPN
fnp-5156	1	178	york	york	PROPN
fnp-5156	1	179	,	,	PUNCT
fnp-5156	1	180	new	new	PROPN
fnp-5156	1	181	york	york	PROPN
fnp-5156	1	182	,	,	PUNCT
fnp-5156	1	183	usa	usa	PROPN
fnp-5156	1	184	department	department	PROPN
fnp-5156	1	185	of	of	ADP
fnp-5156	1	186	neuropathology	neuropathology	NOUN
fnp-5156	1	187	,	,	PUNCT
fnp-5156	1	188	charité	charité	PROPN
fnp-5156	1	189	universitätsmedizin	universitätsmedizin	PROPN
fnp-5156	1	190	berlin	berlin	PROPN
fnp-5156	1	191	,	,	PUNCT
fnp-5156	1	192	berlin	berlin	PROPN
fnp-5156	1	193	,	,	PUNCT
fnp-5156	1	194	germany	germany	PROPN
fnp-5156	1	195	;	;	PUNCT
fnp-5156	1	196	german	german	ADJ
fnp-5156	1	197	cancer	cancer	NOUN
fnp-5156	1	198	consortium	consortium	NOUN
fnp-5156	1	199	(	(	PUNCT
fnp-5156	1	200	dktk	dktk	NOUN
fnp-5156	1	201	)	)	PUNCT
fnp-5156	1	202	,	,	PUNCT
fnp-5156	1	203	berlin	berlin	PROPN
fnp-5156	1	204	,	,	PUNCT
fnp-5156	1	205	germany	germany	PROPN
fnp-5156	1	206	;	;	PUNCT
fnp-5156	1	207	german	german	ADJ
fnp-5156	1	208	cancer	cancer	NOUN
fnp-5156	1	209	research	research	NOUN
fnp-5156	1	210	center	center	NOUN
fnp-5156	1	211	(	(	PUNCT
fnp-5156	1	212	dkfz	dkfz	PROPN
fnp-5156	1	213	)	)	PUNCT
fnp-5156	1	214	,	,	PUNCT
fnp-5156	1	215	heidelberg	heidelberg	PROPN
fnp-5156	1	216	,	,	PUNCT
fnp-5156	1	217	germany	germany	PROPN
fnp-5156	1	218	division	division	NOUN
fnp-5156	1	219	of	of	ADP
fnp-5156	1	220	pediatric	pediatric	ADJ
fnp-5156	1	221	neurooncology	neurooncology	NOUN
fnp-5156	1	222	,	,	PUNCT
fnp-5156	1	223	german	german	ADJ
fnp-5156	1	224	cancer	cancer	NOUN
fnp-5156	1	225	consortium	consortium	NOUN
fnp-5156	1	226	(	(	PUNCT
fnp-5156	1	227	dktk	dktk	NOUN
fnp-5156	1	228	)	)	PUNCT
fnp-5156	1	229	and	and	CCONJ
fnp-5156	1	230	german	german	ADJ
fnp-5156	1	231	cancer	cancer	NOUN
fnp-5156	1	232	research	research	NOUN
fnp-5156	1	233	center	center	NOUN
fnp-5156	1	234	(	(	PUNCT
fnp-5156	1	235	dkfz	dkfz	PROPN
fnp-5156	1	236	)	)	PUNCT
fnp-5156	1	237	,	,	PUNCT
fnp-5156	1	238	heidelberg	heidelberg	PROPN
fnp-5156	1	239	,	,	PUNCT
fnp-5156	1	240	germany	germany	PROPN
fnp-5156	1	241	hopp	hopp	PROPN
fnp-5156	1	242	children	children	PROPN
fnp-5156	1	243	’s	’s	PART
fnp-5156	1	244	cancer	cancer	NOUN
fnp-5156	1	245	center	center	PROPN
fnp-5156	1	246	heidelberg	heidelberg	PROPN
fnp-5156	1	247	(	(	PUNCT
fnp-5156	1	248	kitz	kitz	PROPN
fnp-5156	1	249	)	)	PUNCT
fnp-5156	1	250	,	,	PUNCT
fnp-5156	1	251	heidelberg	heidelberg	PROPN
fnp-5156	1	252	,	,	PUNCT
fnp-5156	1	253	germany	germany	PROPN
fnp-5156	1	254	pediatric	pediatric	ADJ
fnp-5156	1	255	glioma	glioma	NOUN
fnp-5156	1	256	research	research	NOUN
fnp-5156	1	257	group	group	NOUN
fnp-5156	1	258	,	,	PUNCT
fnp-5156	1	259	german	german	ADJ
fnp-5156	1	260	cancer	cancer	NOUN
fnp-5156	1	261	research	research	NOUN
fnp-5156	1	262	center	center	NOUN
fnp-5156	1	263	(	(	PUNCT
fnp-5156	1	264	dkfz	dkfz	PROPN
fnp-5156	1	265	)	)	PUNCT
fnp-5156	1	266	,	,	PUNCT
fnp-5156	1	267	heidelberg	heidelberg	PROPN
fnp-5156	1	268	,	,	PUNCT
fnp-5156	1	269	germany	germany	PROPN
fnp-5156	1	270	department	department	PROPN
fnp-5156	1	271	of	of	ADP
fnp-5156	1	272	pediatric	pediatric	ADJ
fnp-5156	1	273	oncology	oncology	NOUN
fnp-5156	1	274	,	,	PUNCT
fnp-5156	1	275	hematology	hematology	NOUN
fnp-5156	1	276	and	and	CCONJ
fnp-5156	1	277	immunology	immunology	NOUN
fnp-5156	1	278	,	,	PUNCT
fnp-5156	1	279	heidelberg	heidelberg	PROPN
fnp-5156	1	280	university	university	PROPN
fnp-5156	1	281	hospital	hospital	NOUN
fnp-5156	1	282	,	,	PUNCT
fnp-5156	1	283	heidelberg	heidelberg	PROPN
fnp-5156	1	284	,	,	PUNCT
fnp-5156	1	285	germany	germany	PROPN
fnp-5156	1	286	corresponding	corresponding	ADJ
fnp-5156	1	287	author	author	NOUN
fnp-5156	1	288	:	:	PUNCT
fnp-5156	1	289	andreas	andreas	PROPN
fnp-5156	1	290	von	von	PROPN
fnp-5156	1	291	deimling	deimling	PROPN
fnp-5156	1	292	·	·	PUNCT
fnp-5156	1	293	department	department	NOUN
fnp-5156	1	294	of	of	ADP
fnp-5156	1	295	neuropathology	neuropathology	NOUN
fnp-5156	1	296	·	·	PUNCT
fnp-5156	1	297	university	university	PROPN
fnp-5156	1	298	of	of	ADP
fnp-5156	1	299	heidelberg	heidelberg	PROPN
fnp-5156	1	300	and	and	CCONJ
fnp-5156	1	301	clinical	clinical	ADJ
fnp-5156	1	302	cooperation	cooperation	NOUN
fnp-5156	1	303	unit	unit	NOUN
fnp-5156	1	304	neuropathology	neuropathology	NOUN
fnp-5156	1	305	·	·	PUNCT
fnp-5156	1	306	german	german	ADJ
fnp-5156	1	307	cancer	cancer	NOUN
fnp-5156	1	308	consortium	consortium	NOUN
fnp-5156	1	309	(	(	PUNCT
fnp-5156	1	310	dktk	dktk	NOUN
fnp-5156	1	311	)	)	PUNCT
fnp-5156	1	312	·	·	PUNCT
fnp-5156	1	313	german	german	ADJ
fnp-5156	1	314	cancer	cancer	NOUN
fnp-5156	1	315	research	research	NOUN
fnp-5156	1	316	center	center	NOUN
fnp-5156	1	317	(	(	PUNCT
fnp-5156	1	318	dkfz	dkfz	PROPN
fnp-5156	1	319	)	)	PUNCT
fnp-5156	1	320	·	·	PUNCT
fnp-5156	1	321	69120	69120	NUM
fnp-5156	1	322	heidelberg	heidelberg	PROPN
fnp-5156	1	323	·	·	PUNCT
fnp-5156	1	324	germany	germany	PROPN
fnp-5156	1	325	andreas.vondeimling@med.uni-heidelberg.de	andreas.vondeimling@med.uni-heidelberg.de	PROPN
fnp-5156	1	326	additional	additional	ADJ
fnp-5156	1	327	resources	resource	NOUN
fnp-5156	1	328	and	and	CCONJ
fnp-5156	1	329	electronic	electronic	ADJ
fnp-5156	1	330	supplementary	supplementary	ADJ
fnp-5156	1	331	material	material	NOUN
fnp-5156	1	332	:	:	PUNCT
fnp-5156	1	333	supplementary	supplementary	ADJ
fnp-5156	1	334	material	material	NOUN
fnp-5156	1	335	submitted	submit	VERB
fnp-5156	1	336	:	:	PUNCT
fnp-5156	1	337	19	19	NUM
fnp-5156	1	338	october	october	PROPN
fnp-5156	1	339	2023	2023	NUM
fnp-5156	1	340	accepted	accept	VERB
fnp-5156	1	341	:	:	PUNCT
fnp-5156	1	342	30	30	NUM
fnp-5156	1	343	october	october	PROPN
fnp-5156	1	344	2023	2023	NUM
fnp-5156	1	345	copyedited	copyedit	VERB
fnp-5156	1	346	by	by	ADP
fnp-5156	1	347	:	:	PUNCT
fnp-5156	1	348	shino	shino	PROPN
fnp-5156	1	349	magaki	magaki	PROPN
fnp-5156	1	350	published	publish	VERB
fnp-5156	1	351	:	:	PUNCT
fnp-5156	1	352	13	13	NUM
fnp-5156	1	353	november	november	PROPN
fnp-5156	1	354	2023	2023	NUM
fnp-5156	1	355	https://doi.org/10.17879/freeneuropathology-2023-5156	https://doi.org/10.17879/freeneuropathology-2023-5156	PROPN
fnp-5156	1	356	keywords	keyword	NOUN
fnp-5156	1	357	:	:	PUNCT
fnp-5156	1	358	pleomorphic	pleomorphic	ADJ
fnp-5156	1	359	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	1	360	,	,	PUNCT
fnp-5156	1	361	pxa	pxa	NOUN
fnp-5156	1	362	,	,	PUNCT
fnp-5156	1	363	copy	copy	VERB
fnp-5156	1	364	number	number	NOUN
fnp-5156	1	365	variations	variation	NOUN
fnp-5156	1	366	,	,	PUNCT
fnp-5156	1	367	cnv	cnv	PROPN
fnp-5156	1	368	,	,	PUNCT
fnp-5156	1	369	methylation	methylation	NOUN
fnp-5156	1	370	,	,	PUNCT
fnp-5156	1	371	classification	classification	NOUN
fnp-5156	1	372	,	,	PUNCT
fnp-5156	1	373	7/10	7/10	NUM
fnp-5156	1	374	signature	signature	NOUN
fnp-5156	1	375	,	,	PUNCT
fnp-5156	1	376	egfr	egfr	NOUN
fnp-5156	1	377	,	,	PUNCT
fnp-5156	1	378	cdkn2a	cdkn2a	PROPN
fnp-5156	1	379	/	/	SYM
fnp-5156	1	380	b	b	NOUN
fnp-5156	1	381	,	,	PUNCT
fnp-5156	1	382	amplification	amplification	NOUN
fnp-5156	1	383	,	,	PUNCT
fnp-5156	1	384	homozygous	homozygous	ADJ
fnp-5156	1	385	deletion	deletion	NOUN
fnp-5156	1	386	abstract	abstract	ADJ
fnp-5156	1	387	pleomorphic	pleomorphic	ADJ
fnp-5156	1	388	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	1	389	(	(	PUNCT
fnp-5156	1	390	pxa	pxa	NOUN
fnp-5156	1	391	)	)	PUNCT
fnp-5156	1	392	poses	pose	VERB
fnp-5156	1	393	a	a	DET
fnp-5156	1	394	diagnostic	diagnostic	ADJ
fnp-5156	1	395	challenge	challenge	NOUN
fnp-5156	1	396	.	.	PUNCT
fnp-5156	2	1	the	the	DET
fnp-5156	2	2	present	present	ADJ
fnp-5156	2	3	study	study	NOUN
fnp-5156	2	4	relies	rely	VERB
fnp-5156	2	5	on	on	ADP
fnp-5156	2	6	methylation	methylation	NOUN
fnp-5156	2	7	-	-	PUNCT
fnp-5156	2	8	based	base	VERB
fnp-5156	2	9	predictions	prediction	NOUN
fnp-5156	2	10	and	and	CCONJ
fnp-5156	2	11	focuses	focus	VERB
fnp-5156	2	12	on	on	ADP
fnp-5156	2	13	copy	copy	NOUN
fnp-5156	2	14	number	number	NOUN
fnp-5156	2	15	variations	variation	NOUN
fnp-5156	2	16	(	(	PUNCT
fnp-5156	2	17	cnv	cnv	NOUN
fnp-5156	2	18	)	)	PUNCT
fnp-5156	2	19	in	in	ADP
fnp-5156	2	20	pxa	pxa	NOUN
fnp-5156	2	21	.	.	PUNCT
fnp-5156	3	1	we	we	PRON
fnp-5156	3	2	identified	identify	VERB
fnp-5156	3	3	551	551	NUM
fnp-5156	3	4	tumors	tumor	NOUN
fnp-5156	3	5	from	from	ADP
fnp-5156	3	6	patients	patient	NOUN
fnp-5156	3	7	having	having	AUX
fnp-5156	3	8	received	receive	VERB
fnp-5156	3	9	the	the	DET
fnp-5156	3	10	histologic	histologic	ADJ
fnp-5156	3	11	diagnosis	diagnosis	NOUN
fnp-5156	3	12	or	or	CCONJ
fnp-5156	3	13	differential	differential	ADJ
fnp-5156	3	14	diagnosis	diagnosis	NOUN
fnp-5156	3	15	pleomorphic	pleomorphic	ADJ
fnp-5156	3	16	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	3	17	(	(	PUNCT
fnp-5156	3	18	pxa	pxa	NOUN
fnp-5156	3	19	)	)	PUNCT
fnp-5156	3	20	uploaded	upload	VERB
fnp-5156	3	21	to	to	ADP
fnp-5156	3	22	the	the	DET
fnp-5156	3	23	web	web	NOUN
fnp-5156	3	24	page	page	NOUN
fnp-5156	3	25	www.molecularneuropathology.org	www.molecularneuropathology.org	NUM
fnp-5156	3	26	.	.	PUNCT
fnp-5156	4	1	of	of	ADP
fnp-5156	4	2	these	these	DET
fnp-5156	4	3	551	551	NUM
fnp-5156	4	4	tumors	tumor	NOUN
fnp-5156	4	5	,	,	PUNCT
fnp-5156	4	6	165	165	NUM
fnp-5156	4	7	received	receive	VERB
fnp-5156	4	8	the	the	DET
fnp-5156	4	9	prediction	prediction	NOUN
fnp-5156	4	10	“	"	PUNCT
fnp-5156	4	11	methylation	methylation	NOUN
fnp-5156	4	12	class	class	NOUN
fnp-5156	4	13	(	(	PUNCT
fnp-5156	4	14	anaplastic	anaplastic	ADJ
fnp-5156	4	15	)	)	PUNCT
fnp-5156	4	16	pleomorphic	pleomorphic	ADJ
fnp-5156	4	17	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	4	18	”	"	PUNCT
fnp-5156	4	19	with	with	ADP
fnp-5156	4	20	a	a	DET
fnp-5156	4	21	calibrated	calibrate	VERB
fnp-5156	4	22	score	score	NOUN
fnp-5156	4	23	>	>	PUNCT
fnp-5156	4	24	=	=	X
fnp-5156	4	25	0.9	0.9	NUM
fnp-5156	4	26	by	by	ADP
fnp-5156	4	27	the	the	DET
fnp-5156	4	28	brain	brain	NOUN
fnp-5156	4	29	tumor	tumor	NOUN
fnp-5156	4	30	classifier	classifier	NOUN
fnp-5156	4	31	version	version	PROPN
fnp-5156	4	32	v12.8	v12.8	PROPN
fnp-5156	4	33	and	and	CCONJ
fnp-5156	4	34	,	,	PUNCT
fnp-5156	4	35	therefore	therefore	ADV
fnp-5156	4	36	,	,	PUNCT
fnp-5156	4	37	were	be	AUX
fnp-5156	4	38	defined	define	VERB
fnp-5156	4	39	the	the	DET
fnp-5156	4	40	pxa	pxa	NOUN
fnp-5156	4	41	reference	reference	NOUN
fnp-5156	4	42	set	set	VERB
fnp-5156	4	43	designated	designate	VERB
fnp-5156	4	44	mcpxaref	mcpxaref	NOUN
fnp-5156	4	45	.	.	PUNCT
fnp-5156	5	1	in	in	ADP
fnp-5156	5	2	addition	addition	NOUN
fnp-5156	5	3	to	to	ADP
fnp-5156	5	4	these	these	DET
fnp-5156	5	5	165	165	NUM
fnp-5156	5	6	mcpxaref	mcpxaref	NOUN
fnp-5156	5	7	,	,	PUNCT
fnp-5156	5	8	767	767	NUM
fnp-5156	5	9	other	other	ADJ
fnp-5156	5	10	tumors	tumor	NOUN
fnp-5156	5	11	received	receive	VERB
fnp-5156	5	12	the	the	DET
fnp-5156	5	13	prediction	prediction	NOUN
fnp-5156	5	14	mcpxa	mcpxa	NOUN
fnp-5156	5	15	with	with	ADP
fnp-5156	5	16	a	a	DET
fnp-5156	5	17	calibrated	calibrate	VERB
fnp-5156	5	18	score	score	NOUN
fnp-5156	5	19	>	>	PUNCT
fnp-5156	5	20	=	=	X
fnp-5156	5	21	0.9	0.9	NUM
fnp-5156	5	22	but	but	CCONJ
fnp-5156	5	23	without	without	ADP
fnp-5156	5	24	a	a	DET
fnp-5156	5	25	histological	histological	ADJ
fnp-5156	5	26	pxa	pxa	NOUN
fnp-5156	5	27	diagnosis	diagnosis	NOUN
fnp-5156	5	28	.	.	PUNCT
fnp-5156	6	1	the	the	DET
fnp-5156	6	2	total	total	ADJ
fnp-5156	6	3	number	number	NOUN
fnp-5156	6	4	of	of	ADP
fnp-5156	6	5	individual	individual	ADJ
fnp-5156	6	6	tumors	tumor	NOUN
fnp-5156	6	7	predicted	predict	VERB
fnp-5156	6	8	by	by	ADP
fnp-5156	6	9	histology	histology	NOUN
fnp-5156	6	10	and/or	and/or	CCONJ
fnp-5156	6	11	by	by	ADP
fnp-5156	6	12	methylome	methylome	PROPN
fnp-5156	6	13	based	base	VERB
fnp-5156	6	14	classification	classification	NOUN
fnp-5156	6	15	as	as	ADP
fnp-5156	6	16	pxa	pxa	NOUN
fnp-5156	6	17	,	,	PUNCT
fnp-5156	6	18	mcpxa	mcpxa	NOUN
fnp-5156	6	19	or	or	CCONJ
fnp-5156	6	20	both	both	PRON
fnp-5156	6	21	was	be	AUX
fnp-5156	6	22	1318	1318	NUM
fnp-5156	6	23	,	,	PUNCT
fnp-5156	6	24	and	and	CCONJ
fnp-5156	6	25	these	these	PRON
fnp-5156	6	26	were	be	AUX
fnp-5156	6	27	designated	designate	VERB
fnp-5156	6	28	the	the	DET
fnp-5156	6	29	study	study	NOUN
fnp-5156	6	30	cohort	cohort	NOUN
fnp-5156	6	31	.	.	PUNCT
fnp-5156	7	1	the	the	DET
fnp-5156	7	2	selection	selection	NOUN
fnp-5156	7	3	of	of	ADP
fnp-5156	7	4	a	a	DET
fnp-5156	7	5	control	control	NOUN
fnp-5156	7	6	cohort	cohort	NOUN
fnp-5156	7	7	was	be	AUX
fnp-5156	7	8	guided	guide	VERB
fnp-5156	7	9	by	by	ADP
fnp-5156	7	10	methylation	methylation	NOUN
fnp-5156	7	11	-	-	PUNCT
fnp-5156	7	12	based	base	VERB
fnp-5156	7	13	predictions	prediction	NOUN
fnp-5156	7	14	recurrently	recurrently	ADV
fnp-5156	7	15	observed	observe	VERB
fnp-5156	7	16	for	for	ADP
fnp-5156	7	17	the	the	DET
fnp-5156	7	18	other	other	ADJ
fnp-5156	7	19	386/551	386/551	PROPN
fnp-5156	7	20	tumors	tumor	NOUN
fnp-5156	7	21	diagnosed	diagnose	VERB
fnp-5156	7	22	as	as	ADP
fnp-5156	7	23	histologic	histologic	ADJ
fnp-5156	7	24	pxa	pxa	NOUN
fnp-5156	7	25	.	.	PUNCT
fnp-5156	8	1	131/386	131/386	NUM
fnp-5156	8	2	received	receive	VERB
fnp-5156	8	3	predictions	prediction	NOUN
fnp-5156	8	4	for	for	ADP
fnp-5156	8	5	another	another	DET
fnp-5156	8	6	entity	entity	NOUN
fnp-5156	8	7	besides	besides	SCONJ
fnp-5156	8	8	pxa	pxa	NOUN
fnp-5156	8	9	with	with	ADP
fnp-5156	8	10	a	a	DET
fnp-5156	8	11	score	score	NOUN
fnp-5156	8	12	>	>	PUNCT
fnp-5156	8	13	=	=	SYM
fnp-5156	8	14	0.9	0.9	NUM
fnp-5156	8	15	.	.	PUNCT
fnp-5156	9	1	control	control	NOUN
fnp-5156	9	2	tumors	tumor	NOUN
fnp-5156	9	3	corresponding	correspond	VERB
fnp-5156	9	4	to	to	ADP
fnp-5156	9	5	the	the	DET
fnp-5156	9	6	11	11	NUM
fnp-5156	9	7	most	most	ADV
fnp-5156	9	8	common	common	ADJ
fnp-5156	9	9	other	other	ADJ
fnp-5156	9	10	predictions	prediction	NOUN
fnp-5156	9	11	were	be	AUX
fnp-5156	9	12	selected	select	VERB
fnp-5156	9	13	,	,	PUNCT
fnp-5156	9	14	adding	add	VERB
fnp-5156	9	15	up	up	ADP
fnp-5156	9	16	to	to	ADP
fnp-5156	9	17	1100	1100	NUM
fnp-5156	9	18	reference	reference	NOUN
fnp-5156	9	19	cases	case	NOUN
fnp-5156	9	20	.	.	PUNCT
fnp-5156	10	1	cnv	cnv	NOUN
fnp-5156	10	2	profiles	profile	NOUN
fnp-5156	10	3	were	be	AUX
fnp-5156	10	4	calculated	calculate	VERB
fnp-5156	10	5	from	from	ADP
fnp-5156	10	6	all	all	DET
fnp-5156	10	7	methylation	methylation	NOUN
fnp-5156	10	8	datasets	dataset	NOUN
fnp-5156	10	9	of	of	ADP
fnp-5156	10	10	the	the	DET
fnp-5156	10	11	study	study	NOUN
fnp-5156	10	12	and	and	CCONJ
fnp-5156	10	13	control	control	NOUN
fnp-5156	10	14	cohorts	cohort	NOUN
fnp-5156	10	15	.	.	PUNCT
fnp-5156	11	1	special	special	ADJ
fnp-5156	11	2	attention	attention	NOUN
fnp-5156	11	3	was	be	AUX
fnp-5156	11	4	given	give	VERB
fnp-5156	11	5	to	to	ADP
fnp-5156	11	6	the	the	DET
fnp-5156	11	7	7/10	7/10	NUM
fnp-5156	11	8	signature	signature	NOUN
fnp-5156	11	9	,	,	PUNCT
fnp-5156	11	10	gene	gene	NOUN
fnp-5156	11	11	amplifications	amplification	NOUN
fnp-5156	11	12	and	and	CCONJ
fnp-5156	11	13	homozygous	homozygous	ADJ
fnp-5156	11	14	deletion	deletion	NOUN
fnp-5156	11	15	of	of	ADP
fnp-5156	11	16	cdkn2a	cdkn2a	PROPN
fnp-5156	11	17	/	/	SYM
fnp-5156	11	18	b.	b.	PROPN
fnp-5156	11	19	comparison	comparison	NOUN
fnp-5156	11	20	of	of	ADP
fnp-5156	11	21	cnv	cnv	PROPN
fnp-5156	11	22	in	in	ADP
fnp-5156	11	23	the	the	DET
fnp-5156	11	24	subsets	subset	NOUN
fnp-5156	11	25	of	of	ADP
fnp-5156	11	26	the	the	DET
fnp-5156	11	27	study	study	NOUN
fnp-5156	11	28	cohort	cohort	NOUN
fnp-5156	11	29	and	and	CCONJ
fnp-5156	11	30	the	the	DET
fnp-5156	11	31	control	control	NOUN
fnp-5156	11	32	cohort	cohort	NOUN
fnp-5156	11	33	were	be	AUX
fnp-5156	11	34	used	use	VERB
fnp-5156	11	35	to	to	PART
fnp-5156	11	36	establish	establish	VERB
fnp-5156	11	37	relations	relation	NOUN
fnp-5156	11	38	independent	independent	ADJ
fnp-5156	11	39	of	of	ADP
fnp-5156	11	40	histological	histological	ADJ
fnp-5156	11	41	diagnoses	diagnosis	NOUN
fnp-5156	11	42	.	.	PUNCT
fnp-5156	12	1	tumors	tumor	NOUN
fnp-5156	12	2	in	in	ADP
fnp-5156	12	3	mcpxa	mcpxa	PROPN
fnp-5156	12	4	were	be	AUX
fnp-5156	12	5	highly	highly	ADV
fnp-5156	12	6	homogenous	homogenous	ADJ
fnp-5156	12	7	in	in	ADP
fnp-5156	12	8	regard	regard	NOUN
fnp-5156	12	9	to	to	ADP
fnp-5156	12	10	cnv	cnv	PROPN
fnp-5156	12	11	alterations	alteration	NOUN
fnp-5156	12	12	,	,	PUNCT
fnp-5156	12	13	irrespective	irrespective	ADV
fnp-5156	12	14	of	of	ADP
fnp-5156	12	15	the	the	DET
fnp-5156	12	16	histological	histological	ADJ
fnp-5156	12	17	diagnoses	diagnosis	NOUN
fnp-5156	12	18	.	.	PUNCT
fnp-5156	13	1	the	the	DET
fnp-5156	13	2	7/10	7/10	NUM
fnp-5156	13	3	signature	signature	NOUN
fnp-5156	13	4	commonly	commonly	ADV
fnp-5156	13	5	present	present	ADJ
fnp-5156	13	6	in	in	ADP
fnp-5156	13	7	glioblastoma	glioblastoma	NOUN
fnp-5156	13	8	,	,	PUNCT
fnp-5156	13	9	idh	idh	NOUN
fnp-5156	13	10	-	-	PUNCT
fnp-5156	13	11	wildtype	wildtype	NOUN
fnp-5156	13	12	,	,	PUNCT
fnp-5156	13	13	was	be	AUX
fnp-5156	13	14	present	present	ADJ
fnp-5156	13	15	in	in	ADP
fnp-5156	13	16	15	15	NUM
fnp-5156	13	17	-	-	SYM
fnp-5156	13	18	20	20	NUM
fnp-5156	13	19	%	%	NOUN
fnp-5156	13	20	of	of	ADP
fnp-5156	13	21	mcpxa	mcpxa	NOUN
fnp-5156	13	22	,	,	PUNCT
fnp-5156	13	23	whereas	whereas	SCONJ
fnp-5156	13	24	amplification	amplification	NOUN
fnp-5156	13	25	of	of	ADP
fnp-5156	13	26	oncogenes	oncogene	NOUN
fnp-5156	13	27	(	(	PUNCT
fnp-5156	13	28	likewise	likewise	ADV
fnp-5156	13	29	common	common	ADJ
fnp-5156	13	30	in	in	ADP
fnp-5156	13	31	glioblastoma	glioblastoma	NOUN
fnp-5156	13	32	)	)	PUNCT
fnp-5156	13	33	was	be	AUX
fnp-5156	13	34	very	very	ADV
fnp-5156	13	35	rare	rare	ADJ
fnp-5156	13	36	in	in	ADP
fnp-5156	13	37	mcpxa	mcpxa	NOUN
fnp-5156	13	38	(	(	PUNCT
fnp-5156	13	39	<	<	X
fnp-5156	13	40	1	1	NUM
fnp-5156	13	41	%	%	NOUN
fnp-5156	13	42	)	)	PUNCT
fnp-5156	13	43	.	.	PUNCT
fnp-5156	14	1	in	in	ADP
fnp-5156	14	2	contrast	contrast	NOUN
fnp-5156	14	3	,	,	PUNCT
fnp-5156	14	4	the	the	DET
fnp-5156	14	5	histology	histology	NOUN
fnp-5156	14	6	-	-	PUNCT
fnp-5156	14	7	based	base	VERB
fnp-5156	14	8	pxa	pxa	NOUN
fnp-5156	14	9	group	group	NOUN
fnp-5156	14	10	exhibited	exhibit	VERB
fnp-5156	14	11	high	high	ADJ
fnp-5156	14	12	variance	variance	NOUN
fnp-5156	14	13	in	in	ADP
fnp-5156	14	14	regard	regard	NOUN
fnp-5156	14	15	to	to	ADP
fnp-5156	14	16	methylation	methylation	NOUN
fnp-5156	14	17	classes	class	NOUN
fnp-5156	14	18	as	as	ADV
fnp-5156	14	19	well	well	ADV
fnp-5156	14	20	as	as	ADP
fnp-5156	14	21	to	to	PART
fnp-5156	14	22	cnvs	cnvs	VERB
fnp-5156	14	23	.	.	PUNCT
fnp-5156	15	1	our	our	PRON
fnp-5156	15	2	data	datum	NOUN
fnp-5156	15	3	add	add	VERB
fnp-5156	15	4	to	to	ADP
fnp-5156	15	5	the	the	DET
fnp-5156	15	6	notion	notion	NOUN
fnp-5156	15	7	,	,	PUNCT
fnp-5156	15	8	that	that	DET
fnp-5156	15	9	histologically	histologically	ADV
fnp-5156	15	10	defined	define	VERB
fnp-5156	15	11	pxa	pxa	NOUN
fnp-5156	15	12	likely	likely	ADV
fnp-5156	15	13	only	only	ADV
fnp-5156	15	14	represent	represent	VERB
fnp-5156	15	15	a	a	DET
fnp-5156	15	16	subset	subset	NOUN
fnp-5156	15	17	of	of	ADP
fnp-5156	15	18	the	the	DET
fnp-5156	15	19	biological	biological	ADJ
fnp-5156	15	20	disease	disease	NOUN
fnp-5156	15	21	.	.	PUNCT
fnp-5156	16	1	introduction	introduction	NOUN
fnp-5156	16	2	since	since	SCONJ
fnp-5156	16	3	its	its	PRON
fnp-5156	16	4	first	first	ADJ
fnp-5156	16	5	description	description	NOUN
fnp-5156	16	6	in	in	ADP
fnp-5156	16	7	1979	1979	NUM
fnp-5156	16	8	(	(	PUNCT
fnp-5156	16	9	1	1	NUM
fnp-5156	16	10	)	)	PUNCT
fnp-5156	16	11	,	,	PUNCT
fnp-5156	16	12	pleomorphic	pleomorphic	ADJ
fnp-5156	16	13	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	16	14	(	(	PUNCT
fnp-5156	16	15	pxa	pxa	NOUN
fnp-5156	16	16	)	)	PUNCT
fnp-5156	16	17	has	have	AUX
fnp-5156	16	18	posed	pose	VERB
fnp-5156	16	19	a	a	DET
fnp-5156	16	20	notable	notable	ADJ
fnp-5156	16	21	diagnostic	diagnostic	ADJ
fnp-5156	16	22	challenge	challenge	NOUN
fnp-5156	16	23	.	.	PUNCT
fnp-5156	17	1	opinions	opinion	NOUN
fnp-5156	17	2	on	on	ADP
fnp-5156	17	3	appropriate	appropriate	ADJ
fnp-5156	17	4	diagnostic	diagnostic	ADJ
fnp-5156	17	5	parameters	parameter	NOUN
fnp-5156	17	6	vary	vary	VERB
fnp-5156	17	7	,	,	PUNCT
fnp-5156	17	8	resulting	result	VERB
fnp-5156	17	9	in	in	ADP
fnp-5156	17	10	debates	debate	NOUN
fnp-5156	17	11	on	on	ADP
fnp-5156	17	12	the	the	DET
fnp-5156	17	13	defining	define	VERB
fnp-5156	17	14	characteristics	characteristic	NOUN
fnp-5156	17	15	of	of	ADP
fnp-5156	17	16	the	the	DET
fnp-5156	17	17	entity	entity	NOUN
fnp-5156	17	18	itself	itself	PRON
fnp-5156	17	19	as	as	ADV
fnp-5156	17	20	well	well	ADV
fnp-5156	17	21	as	as	ADP
fnp-5156	17	22	on	on	ADP
fnp-5156	17	23	the	the	DET
fnp-5156	17	24	diagnosis	diagnosis	NOUN
fnp-5156	17	25	of	of	ADP
fnp-5156	17	26	many	many	ADJ
fnp-5156	17	27	individual	individual	ADJ
fnp-5156	17	28	tumors	tumor	NOUN
fnp-5156	17	29	.	.	PUNCT
fnp-5156	18	1	the	the	DET
fnp-5156	18	2	current	current	NOUN
fnp-5156	18	3	who	who	PRON
fnp-5156	18	4	classification	classification	NOUN
fnp-5156	18	5	renders	render	VERB
fnp-5156	18	6	specific	specific	ADJ
fnp-5156	18	7	morphological	morphological	ADJ
fnp-5156	18	8	features	feature	NOUN
fnp-5156	18	9	including	include	VERB
fnp-5156	18	10	pleomorphism	pleomorphism	NOUN
fnp-5156	18	11	,	,	PUNCT
fnp-5156	18	12	presence	presence	NOUN
fnp-5156	18	13	of	of	ADP
fnp-5156	18	14	multinucleated	multinucleate	VERB
fnp-5156	18	15	as	as	ADV
fnp-5156	18	16	well	well	ADV
fnp-5156	18	17	as	as	ADP
fnp-5156	18	18	spindle	spindle	ADJ
fnp-5156	18	19	cells	cell	NOUN
fnp-5156	18	20	,	,	PUNCT
fnp-5156	18	21	xanthomatous	xanthomatous	ADJ
fnp-5156	18	22	cells	cell	NOUN
fnp-5156	18	23	and	and	CCONJ
fnp-5156	18	24	eosinophilic	eosinophilic	ADJ
fnp-5156	18	25	granular	granular	ADJ
fnp-5156	18	26	bodies	body	NOUN
fnp-5156	18	27	as	as	ADP
fnp-5156	18	28	essential	essential	ADJ
fnp-5156	18	29	(	(	PUNCT
fnp-5156	18	30	2,3	2,3	NUM
fnp-5156	18	31	)	)	PUNCT
fnp-5156	18	32	.	.	PUNCT
fnp-5156	19	1	molecular	molecular	ADJ
fnp-5156	19	2	alterations	alteration	NOUN
fnp-5156	19	3	including	include	VERB
fnp-5156	19	4	braf	braf	NOUN
fnp-5156	19	5	mutation	mutation	NOUN
fnp-5156	19	6	,	,	PUNCT
fnp-5156	19	7	homozygous	homozygous	ADJ
fnp-5156	19	8	deletion	deletion	NOUN
fnp-5156	19	9	of	of	ADP
fnp-5156	19	10	cdkn2a	cdkn2a	PROPN
fnp-5156	19	11	/	/	SYM
fnp-5156	19	12	b	b	PROPN
fnp-5156	19	13	and	and	CCONJ
fnp-5156	19	14	the	the	DET
fnp-5156	19	15	methylome	methylome	ADJ
fnp-5156	19	16	profile	profile	NOUN
fnp-5156	19	17	of	of	ADP
fnp-5156	19	18	pxa	pxa	NOUN
fnp-5156	19	19	(	(	PUNCT
fnp-5156	19	20	mcpxa	mcpxa	NOUN
fnp-5156	19	21	)	)	PUNCT
fnp-5156	19	22	are	be	AUX
fnp-5156	19	23	currently	currently	ADV
fnp-5156	19	24	considered	consider	VERB
fnp-5156	19	25	as	as	ADP
fnp-5156	19	26	desirable	desirable	ADJ
fnp-5156	19	27	criteria	criterion	NOUN
fnp-5156	19	28	for	for	ADP
fnp-5156	19	29	confirming	confirm	VERB
fnp-5156	19	30	a	a	DET
fnp-5156	19	31	diagnosis	diagnosis	NOUN
fnp-5156	19	32	.	.	PUNCT
fnp-5156	20	1	a	a	DET
fnp-5156	20	2	major	major	ADJ
fnp-5156	20	3	problem	problem	NOUN
fnp-5156	20	4	is	be	AUX
fnp-5156	20	5	that	that	SCONJ
fnp-5156	20	6	only	only	ADV
fnp-5156	20	7	a	a	DET
fnp-5156	20	8	fraction	fraction	NOUN
fnp-5156	20	9	of	of	ADP
fnp-5156	20	10	tumors	tumor	NOUN
fnp-5156	20	11	receiving	receive	VERB
fnp-5156	20	12	the	the	DET
fnp-5156	20	13	prediction	prediction	NOUN
fnp-5156	20	14	mcpxa	mcpxa	NOUN
fnp-5156	20	15	do	do	AUX
fnp-5156	20	16	exhibit	exhibit	VERB
fnp-5156	20	17	the	the	DET
fnp-5156	20	18	classical	classical	ADJ
fnp-5156	20	19	morphological	morphological	ADJ
fnp-5156	20	20	features	feature	NOUN
fnp-5156	20	21	of	of	ADP
fnp-5156	20	22	pxa	pxa	NOUN
fnp-5156	20	23	(	(	PUNCT
fnp-5156	20	24	and	and	CCONJ
fnp-5156	20	25	conversely	conversely	ADV
fnp-5156	20	26	,	,	PUNCT
fnp-5156	20	27	many	many	ADJ
fnp-5156	20	28	tumors	tumor	NOUN
fnp-5156	20	29	histologically	histologically	ADV
fnp-5156	20	30	called	call	VERB
fnp-5156	20	31	pxa	pxa	NOUN
fnp-5156	20	32	show	show	VERB
fnp-5156	20	33	molecular	molecular	ADJ
fnp-5156	20	34	features	feature	NOUN
fnp-5156	20	35	typical	typical	ADJ
fnp-5156	20	36	of	of	ADP
fnp-5156	20	37	other	other	ADJ
fnp-5156	20	38	entities	entity	NOUN
fnp-5156	20	39	)	)	PUNCT
fnp-5156	20	40	.	.	PUNCT
fnp-5156	21	1	the	the	DET
fnp-5156	21	2	central	central	ADJ
fnp-5156	21	3	dispute	dispute	NOUN
fnp-5156	21	4	revolves	revolve	VERB
fnp-5156	21	5	around	around	ADP
fnp-5156	21	6	the	the	DET
fnp-5156	21	7	question	question	NOUN
fnp-5156	21	8	,	,	PUNCT
fnp-5156	21	9	how	how	SCONJ
fnp-5156	21	10	tumors	tumor	NOUN
fnp-5156	21	11	with	with	ADP
fnp-5156	21	12	a	a	DET
fnp-5156	21	13	methylation	methylation	NOUN
fnp-5156	21	14	profile	profile	NOUN
fnp-5156	21	15	of	of	ADP
fnp-5156	21	16	pxa	pxa	NOUN
fnp-5156	21	17	lacking	lack	VERB
fnp-5156	21	18	the	the	DET
fnp-5156	21	19	histological	histological	ADJ
fnp-5156	21	20	hallmarks	hallmark	NOUN
fnp-5156	21	21	should	should	AUX
fnp-5156	21	22	be	be	AUX
fnp-5156	21	23	classified	classify	VERB
fnp-5156	21	24	.	.	PUNCT
fnp-5156	22	1	several	several	ADJ
fnp-5156	22	2	studies	study	NOUN
fnp-5156	22	3	have	have	AUX
fnp-5156	22	4	addressed	address	VERB
fnp-5156	22	5	this	this	DET
fnp-5156	22	6	problem	problem	NOUN
fnp-5156	22	7	without	without	ADP
fnp-5156	22	8	coming	come	VERB
fnp-5156	22	9	to	to	ADP
fnp-5156	22	10	a	a	DET
fnp-5156	22	11	consensus	consensus	NOUN
fnp-5156	22	12	as	as	ADP
fnp-5156	22	13	for	for	ADP
fnp-5156	22	14	now	now	ADV
fnp-5156	22	15	(	(	PUNCT
fnp-5156	22	16	4	4	NUM
fnp-5156	22	17	-	-	SYM
fnp-5156	22	18	7	7	NUM
fnp-5156	22	19	)	)	PUNCT
fnp-5156	22	20	.	.	PUNCT
fnp-5156	23	1	the	the	DET
fnp-5156	23	2	present	present	ADJ
fnp-5156	23	3	study	study	NOUN
fnp-5156	23	4	has	have	VERB
fnp-5156	23	5	a	a	DET
fnp-5156	23	6	very	very	ADV
fnp-5156	23	7	limited	limited	ADJ
fnp-5156	23	8	scope	scope	NOUN
fnp-5156	23	9	addressing	address	VERB
fnp-5156	23	10	only	only	ADV
fnp-5156	23	11	the	the	DET
fnp-5156	23	12	three	three	NUM
fnp-5156	23	13	parameters	parameter	NOUN
fnp-5156	23	14	:	:	PUNCT
fnp-5156	23	15	the	the	DET
fnp-5156	23	16	initial	initial	ADJ
fnp-5156	23	17	histological	histological	ADJ
fnp-5156	23	18	diagnosis	diagnosis	NOUN
fnp-5156	23	19	,	,	PUNCT
fnp-5156	23	20	the	the	DET
fnp-5156	23	21	dna	dna	PROPN
fnp-5156	23	22	methylation	methylation	NOUN
fnp-5156	23	23	-	-	PUNCT
fnp-5156	23	24	based	base	VERB
fnp-5156	23	25	tumor	tumor	NOUN
fnp-5156	23	26	prediction	prediction	NOUN
fnp-5156	23	27	and	and	CCONJ
fnp-5156	23	28	copy	copy	VERB
fnp-5156	23	29	number	number	NOUN
fnp-5156	23	30	variations	variation	NOUN
fnp-5156	23	31	(	(	PUNCT
fnp-5156	23	32	cnvs	cnvs	NOUN
fnp-5156	23	33	)	)	PUNCT
fnp-5156	23	34	.	.	PUNCT
fnp-5156	24	1	thus	thus	ADV
fnp-5156	24	2	,	,	PUNCT
fnp-5156	24	3	in	in	ADP
fnp-5156	24	4	932	932	NUM
fnp-5156	24	5	tumors	tumor	NOUN
fnp-5156	24	6	with	with	ADP
fnp-5156	24	7	a	a	DET
fnp-5156	24	8	heidelberg	heidelberg	NOUN
fnp-5156	24	9	classifier	classifier	NOUN
fnp-5156	24	10	prediction	prediction	NOUN
fnp-5156	24	11	of	of	ADP
fnp-5156	24	12	mcpxa	mcpxa	NOUN
fnp-5156	24	13	,	,	PUNCT
fnp-5156	24	14	the	the	DET
fnp-5156	24	15	only	only	ADJ
fnp-5156	24	16	additional	additional	ADJ
fnp-5156	24	17	parameters	parameter	NOUN
fnp-5156	24	18	addressed	address	VERB
fnp-5156	24	19	are	be	AUX
fnp-5156	24	20	initial	initial	ADJ
fnp-5156	24	21	diagnosis	diagnosis	NOUN
fnp-5156	24	22	and	and	CCONJ
fnp-5156	24	23	cnvs	cnvs	NOUN
fnp-5156	24	24	.	.	PUNCT
fnp-5156	25	1	conveniently	conveniently	ADV
fnp-5156	25	2	,	,	PUNCT
fnp-5156	25	3	cnvs	cnvs	NOUN
fnp-5156	25	4	can	can	AUX
fnp-5156	25	5	be	be	AUX
fnp-5156	25	6	read	read	VERB
fnp-5156	25	7	out	out	ADP
fnp-5156	25	8	of	of	ADP
fnp-5156	25	9	array	array	NOUN
fnp-5156	25	10	-	-	PUNCT
fnp-5156	25	11	based	base	VERB
fnp-5156	25	12	methylome	methylome	ADJ
fnp-5156	25	13	data	datum	NOUN
fnp-5156	25	14	and	and	CCONJ
fnp-5156	25	15	allow	allow	VERB
fnp-5156	25	16	for	for	ADP
fnp-5156	25	17	the	the	DET
fnp-5156	25	18	determination	determination	NOUN
fnp-5156	25	19	of	of	ADP
fnp-5156	25	20	chromosomal	chromosomal	ADJ
fnp-5156	25	21	losses	loss	NOUN
fnp-5156	25	22	and	and	CCONJ
fnp-5156	25	23	gains	gain	NOUN
fnp-5156	25	24	including	include	VERB
fnp-5156	25	25	gene	gene	NOUN
fnp-5156	25	26	amplifications	amplification	NOUN
fnp-5156	25	27	and	and	CCONJ
fnp-5156	25	28	homozygous	homozygous	ADJ
fnp-5156	25	29	deletions	deletion	NOUN
fnp-5156	25	30	.	.	PUNCT
fnp-5156	26	1	we	we	PRON
fnp-5156	26	2	determined	determine	VERB
fnp-5156	26	3	the	the	DET
fnp-5156	26	4	distribution	distribution	NOUN
fnp-5156	26	5	of	of	ADP
fnp-5156	26	6	cnvs	cnvs	NOUN
fnp-5156	26	7	focusing	focus	VERB
fnp-5156	26	8	on	on	ADP
fnp-5156	26	9	regions	region	NOUN
fnp-5156	26	10	and	and	CCONJ
fnp-5156	26	11	genes	gene	NOUN
fnp-5156	26	12	known	know	VERB
fnp-5156	26	13	to	to	PART
fnp-5156	26	14	be	be	AUX
fnp-5156	26	15	relevant	relevant	ADJ
fnp-5156	26	16	in	in	ADP
fnp-5156	26	17	pxa	pxa	NOUN
fnp-5156	26	18	and	and	CCONJ
fnp-5156	26	19	other	other	ADJ
fnp-5156	26	20	morphological	morphological	ADJ
fnp-5156	26	21	mimics	mimic	NOUN
fnp-5156	26	22	.	.	PUNCT
fnp-5156	27	1	based	base	VERB
fnp-5156	27	2	on	on	ADP
fnp-5156	27	3	the	the	DET
fnp-5156	27	4	large	large	ADJ
fnp-5156	27	5	number	number	NOUN
fnp-5156	27	6	of	of	ADP
fnp-5156	27	7	datasets	dataset	NOUN
fnp-5156	27	8	included	include	VERB
fnp-5156	27	9	,	,	PUNCT
fnp-5156	27	10	the	the	DET
fnp-5156	27	11	conclusions	conclusion	NOUN
fnp-5156	27	12	can	can	AUX
fnp-5156	27	13	be	be	AUX
fnp-5156	27	14	considered	consider	VERB
fnp-5156	27	15	very	very	ADV
fnp-5156	27	16	robust	robust	ADJ
fnp-5156	27	17	despite	despite	SCONJ
fnp-5156	27	18	the	the	DET
fnp-5156	27	19	intentional	intentional	ADJ
fnp-5156	27	20	limitations	limitation	NOUN
fnp-5156	27	21	on	on	ADP
fnp-5156	27	22	scope	scope	NOUN
fnp-5156	27	23	.	.	PUNCT
fnp-5156	28	1	material	material	NOUN
fnp-5156	28	2	and	and	CCONJ
fnp-5156	28	3	methods	method	NOUN
fnp-5156	28	4	selection	selection	NOUN
fnp-5156	28	5	of	of	ADP
fnp-5156	28	6	study	study	NOUN
fnp-5156	28	7	and	and	CCONJ
fnp-5156	28	8	control	control	NOUN
fnp-5156	28	9	cohorts	cohort	NOUN
fnp-5156	28	10	the	the	DET
fnp-5156	28	11	basis	basis	NOUN
fnp-5156	28	12	for	for	ADP
fnp-5156	28	13	all	all	DET
fnp-5156	28	14	tumors	tumor	NOUN
fnp-5156	28	15	included	include	VERB
fnp-5156	28	16	in	in	ADP
fnp-5156	28	17	this	this	DET
fnp-5156	28	18	study	study	NOUN
fnp-5156	28	19	was	be	AUX
fnp-5156	28	20	presence	presence	NOUN
fnp-5156	28	21	of	of	ADP
fnp-5156	28	22	an	an	DET
fnp-5156	28	23	illumina	illumina	PROPN
fnp-5156	28	24	humanmethylation450	humanmethylation450	PROPN
fnp-5156	28	25	(	(	PUNCT
fnp-5156	28	26	450k	450k	NOUN
fnp-5156	28	27	)	)	PUNCT
fnp-5156	28	28	or	or	CCONJ
fnp-5156	28	29	epic	epic	ADJ
fnp-5156	28	30	dataset	dataset	NOUN
fnp-5156	28	31	.	.	PUNCT
fnp-5156	29	1	there	there	PRON
fnp-5156	29	2	were	be	VERB
fnp-5156	29	3	120800	120800	NUM
fnp-5156	29	4	tumors	tumor	NOUN
fnp-5156	29	5	in	in	ADP
fnp-5156	29	6	the	the	DET
fnp-5156	29	7	database	database	NOUN
fnp-5156	29	8	of	of	ADP
fnp-5156	29	9	the	the	DET
fnp-5156	29	10	department	department	PROPN
fnp-5156	29	11	of	of	ADP
fnp-5156	29	12	neuropathology	neuropathology	PROPN
fnp-5156	29	13	heidelberg	heidelberg	PROPN
fnp-5156	29	14	and	and	CCONJ
fnp-5156	29	15	german	german	ADJ
fnp-5156	29	16	cancer	cancer	NOUN
fnp-5156	29	17	research	research	NOUN
fnp-5156	29	18	center	center	NOUN
fnp-5156	29	19	(	(	PUNCT
fnp-5156	29	20	dkfz	dkfz	PROPN
fnp-5156	29	21	)	)	PUNCT
fnp-5156	29	22	containing	contain	VERB
fnp-5156	29	23	data	datum	NOUN
fnp-5156	29	24	from	from	ADP
fnp-5156	29	25	the	the	DET
fnp-5156	29	26	heidelberg	heidelberg	NOUN
fnp-5156	29	27	brain	brain	NOUN
fnp-5156	29	28	tumor	tumor	NOUN
fnp-5156	29	29	classifier	classifier	NOUN
fnp-5156	29	30	(	(	PUNCT
fnp-5156	29	31	www.molecularneuropathology.org	www.molecularneuropathology.org	NOUN
fnp-5156	29	32	)	)	PUNCT
fnp-5156	29	33	(	(	PUNCT
fnp-5156	29	34	date	date	NOUN
fnp-5156	29	35	:	:	PUNCT
fnp-5156	29	36	01	01	NUM
fnp-5156	29	37	.	.	PUNCT
fnp-5156	29	38	aug	aug	PROPN
fnp-5156	29	39	.	.	PROPN
fnp-5156	29	40	2023	2023	NUM
fnp-5156	29	41	)	)	PUNCT
fnp-5156	29	42	.	.	PUNCT
fnp-5156	30	1	of	of	ADP
fnp-5156	30	2	these	these	PRON
fnp-5156	30	3	,	,	PUNCT
fnp-5156	30	4	932	932	NUM
fnp-5156	30	5	tumors	tumor	NOUN
fnp-5156	30	6	were	be	AUX
fnp-5156	30	7	predicted	predict	VERB
fnp-5156	30	8	as	as	ADP
fnp-5156	30	9	belonging	belong	VERB
fnp-5156	30	10	to	to	ADP
fnp-5156	30	11	the	the	DET
fnp-5156	30	12	methylation	methylation	NOUN
fnp-5156	30	13	class	class	NOUN
fnp-5156	30	14	pleomorphic	pleomorphic	ADJ
fnp-5156	30	15	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	30	16	(	(	PUNCT
fnp-5156	30	17	mcpxa	mcpxa	NOUN
fnp-5156	30	18	)	)	PUNCT
fnp-5156	30	19	by	by	ADP
fnp-5156	30	20	the	the	DET
fnp-5156	30	21	heidelberg	heidelberg	PROPN
fnp-5156	30	22	brain	brain	NOUN
fnp-5156	30	23	tumor	tumor	NOUN
fnp-5156	30	24	classifier	classifier	PROPN
fnp-5156	30	25	version	version	PROPN
fnp-5156	30	26	12.8	12.8	NUM
fnp-5156	30	27	with	with	ADP
fnp-5156	30	28	a	a	DET
fnp-5156	30	29	calibrated	calibrate	VERB
fnp-5156	30	30	score	score	NOUN
fnp-5156	30	31	>	>	PUNCT
fnp-5156	30	32	=	=	SYM
fnp-5156	30	33	0.9	0.9	NUM
fnp-5156	30	34	.	.	PUNCT
fnp-5156	31	1	version	version	NOUN
fnp-5156	31	2	12.8	12.8	NUM
fnp-5156	31	3	has	have	AUX
fnp-5156	31	4	been	be	AUX
fnp-5156	31	5	further	far	ADV
fnp-5156	31	6	developed	develop	VERB
fnp-5156	31	7	from	from	ADP
fnp-5156	31	8	a	a	DET
fnp-5156	31	9	previously	previously	ADV
fnp-5156	31	10	published	publish	VERB
fnp-5156	31	11	version	version	NOUN
fnp-5156	31	12	11b4	11b4	NUM
fnp-5156	31	13	(	(	PUNCT
fnp-5156	31	14	8)	8)	NUM
fnp-5156	31	15	.	.	PUNCT
fnp-5156	32	1	in	in	ADP
fnp-5156	32	2	an	an	DET
fnp-5156	32	3	independent	independent	ADJ
fnp-5156	32	4	query	query	NOUN
fnp-5156	32	5	,	,	PUNCT
fnp-5156	32	6	we	we	PRON
fnp-5156	32	7	identified	identify	VERB
fnp-5156	32	8	all	all	DET
fnp-5156	32	9	tumors	tumor	NOUN
fnp-5156	32	10	in	in	ADP
fnp-5156	32	11	the	the	DET
fnp-5156	32	12	database	database	NOUN
fnp-5156	32	13	for	for	ADP
fnp-5156	32	14	which	which	PRON
fnp-5156	32	15	the	the	DET
fnp-5156	32	16	histological	histological	ADJ
fnp-5156	32	17	diagnosis	diagnosis	NOUN
fnp-5156	32	18	or	or	CCONJ
fnp-5156	32	19	differential	differential	ADJ
fnp-5156	32	20	diagnosis	diagnosis	NOUN
fnp-5156	32	21	pxa	pxa	NOUN
fnp-5156	32	22	has	have	AUX
fnp-5156	32	23	been	be	AUX
fnp-5156	32	24	disclosed	disclose	VERB
fnp-5156	32	25	by	by	ADP
fnp-5156	32	26	the	the	DET
fnp-5156	32	27	submitters	submitter	NOUN
fnp-5156	32	28	.	.	PUNCT
fnp-5156	33	1	this	this	PRON
fnp-5156	33	2	yielded	yield	VERB
fnp-5156	33	3	551	551	NUM
fnp-5156	33	4	tumors	tumor	NOUN
fnp-5156	33	5	.	.	PUNCT
fnp-5156	34	1	one	one	NUM
fnp-5156	34	2	hundred	hundred	NUM
fnp-5156	34	3	and	and	CCONJ
fnp-5156	34	4	sixty	sixty	NUM
fnp-5156	34	5	-	-	PUNCT
fnp-5156	34	6	five	five	NUM
fnp-5156	34	7	tumors	tumor	NOUN
fnp-5156	34	8	received	receive	VERB
fnp-5156	34	9	both	both	PRON
fnp-5156	34	10	,	,	PUNCT
fnp-5156	34	11	the	the	DET
fnp-5156	34	12	prediction	prediction	NOUN
fnp-5156	34	13	of	of	ADP
fnp-5156	34	14	mcpxa	mcpxa	NOUN
fnp-5156	34	15	and	and	CCONJ
fnp-5156	34	16	the	the	DET
fnp-5156	34	17	diagnosis	diagnosis	NOUN
fnp-5156	34	18	or	or	CCONJ
fnp-5156	34	19	differential	differential	ADJ
fnp-5156	34	20	diagnosis	diagnosis	NOUN
fnp-5156	34	21	pxa	pxa	NOUN
fnp-5156	34	22	and	and	CCONJ
fnp-5156	34	23	these	these	PRON
fnp-5156	34	24	were	be	AUX
fnp-5156	34	25	designated	designate	VERB
fnp-5156	34	26	the	the	DET
fnp-5156	34	27	mcpxa	mcpxa	NOUN
fnp-5156	34	28	reference	reference	NOUN
fnp-5156	34	29	set	set	NOUN
fnp-5156	34	30	(	(	PUNCT
fnp-5156	34	31	mcpxaref	mcpxaref	NOUN
fnp-5156	34	32	)	)	PUNCT
fnp-5156	34	33	.	.	PUNCT
fnp-5156	35	1	thus	thus	ADV
fnp-5156	35	2	,	,	PUNCT
fnp-5156	35	3	the	the	DET
fnp-5156	35	4	central	central	ADJ
fnp-5156	35	5	study	study	NOUN
fnp-5156	35	6	cohort	cohort	NOUN
fnp-5156	35	7	included	include	VERB
fnp-5156	35	8	1318	1318	NUM
fnp-5156	35	9	cases	case	NOUN
fnp-5156	35	10	.	.	PUNCT
fnp-5156	36	1	a	a	DET
fnp-5156	36	2	graphical	graphical	ADJ
fnp-5156	36	3	depiction	depiction	NOUN
fnp-5156	36	4	of	of	ADP
fnp-5156	36	5	the	the	DET
fnp-5156	36	6	study	study	NOUN
fnp-5156	36	7	cohort	cohort	NOUN
fnp-5156	36	8	is	be	AUX
fnp-5156	36	9	provided	provide	VERB
fnp-5156	36	10	in	in	ADP
fnp-5156	36	11	figure	figure	NOUN
fnp-5156	36	12	1	1	NUM
fnp-5156	36	13	.	.	PUNCT
fnp-5156	37	1	an	an	DET
fnp-5156	37	2	overview	overview	NOUN
fnp-5156	37	3	of	of	ADP
fnp-5156	37	4	the	the	DET
fnp-5156	37	5	classifier	classifier	NOUN
fnp-5156	37	6	predictions	prediction	NOUN
fnp-5156	37	7	for	for	ADP
fnp-5156	37	8	551	551	NUM
fnp-5156	37	9	histological	histological	ADJ
fnp-5156	37	10	pxa	pxa	NOUN
fnp-5156	37	11	is	be	AUX
fnp-5156	37	12	given	give	VERB
fnp-5156	37	13	in	in	ADP
fnp-5156	37	14	supplementary	supplementary	ADJ
fnp-5156	37	15	table	table	NOUN
fnp-5156	37	16	1	1	NUM
fnp-5156	37	17	.	.	PUNCT
fnp-5156	38	1	all	all	DET
fnp-5156	38	2	predictions	prediction	NOUN
fnp-5156	38	3	with	with	ADP
fnp-5156	38	4	a	a	DET
fnp-5156	38	5	calibrated	calibrate	VERB
fnp-5156	38	6	score	score	NOUN
fnp-5156	38	7	>	>	PUNCT
fnp-5156	38	8	=	=	NOUN
fnp-5156	38	9	0.9	0.9	NUM
fnp-5156	38	10	occurring	occur	VERB
fnp-5156	38	11	at	at	ADV
fnp-5156	38	12	least	least	ADJ
fnp-5156	38	13	twice	twice	ADV
fnp-5156	38	14	were	be	AUX
fnp-5156	38	15	considered	consider	VERB
fnp-5156	38	16	relevant	relevant	ADJ
fnp-5156	38	17	differential	differential	ADJ
fnp-5156	38	18	molecular	molecular	ADJ
fnp-5156	38	19	diagnoses	diagnosis	NOUN
fnp-5156	38	20	of	of	ADP
fnp-5156	38	21	histological	histological	ADJ
fnp-5156	38	22	pxa	pxa	NOUN
fnp-5156	38	23	.	.	PUNCT
fnp-5156	39	1	reference	reference	NOUN
fnp-5156	39	2	sets	set	NOUN
fnp-5156	39	3	of	of	ADP
fnp-5156	39	4	100	100	NUM
fnp-5156	39	5	corresponding	correspond	VERB
fnp-5156	39	6	tumors	tumor	NOUN
fnp-5156	39	7	for	for	ADP
fnp-5156	39	8	each	each	DET
fnp-5156	39	9	class	class	NOUN
fnp-5156	39	10	were	be	AUX
fnp-5156	39	11	compiled	compile	VERB
fnp-5156	39	12	for	for	ADP
fnp-5156	39	13	eleven	eleven	NUM
fnp-5156	39	14	differential	differential	ADJ
fnp-5156	39	15	diagnoses	diagnosis	NOUN
fnp-5156	39	16	.	.	PUNCT
fnp-5156	40	1	all	all	DET
fnp-5156	40	2	tumors	tumor	NOUN
fnp-5156	40	3	in	in	ADP
fnp-5156	40	4	the	the	DET
fnp-5156	40	5	reference	reference	NOUN
fnp-5156	40	6	sets	set	NOUN
fnp-5156	40	7	received	receive	VERB
fnp-5156	40	8	a	a	DET
fnp-5156	40	9	prediction	prediction	NOUN
fnp-5156	40	10	with	with	ADP
fnp-5156	40	11	a	a	DET
fnp-5156	40	12	calibrated	calibrate	VERB
fnp-5156	40	13	score	score	NOUN
fnp-5156	40	14	>	>	PUNCT
fnp-5156	40	15	=	=	X
fnp-5156	40	16	0.9	0.9	NUM
fnp-5156	40	17	in	in	ADP
fnp-5156	40	18	the	the	DET
fnp-5156	40	19	brain	brain	NOUN
fnp-5156	40	20	tumor	tumor	NOUN
fnp-5156	40	21	classifier	classifier	NOUN
fnp-5156	40	22	v12.8	v12.8	PROPN
fnp-5156	40	23	.	.	PUNCT
fnp-5156	41	1	this	this	PRON
fnp-5156	41	2	resulted	result	VERB
fnp-5156	41	3	in	in	ADP
fnp-5156	41	4	a	a	DET
fnp-5156	41	5	reference	reference	NOUN
fnp-5156	41	6	cohort	cohort	NOUN
fnp-5156	41	7	totaling	total	VERB
fnp-5156	41	8	1100	1100	NUM
fnp-5156	41	9	methylation	methylation	NOUN
fnp-5156	41	10	datasets	dataset	NOUN
fnp-5156	41	11	.	.	PUNCT
fnp-5156	42	1	figure	figure	NOUN
fnp-5156	42	2	1	1	NUM
fnp-5156	42	3	:	:	PUNCT
fnp-5156	42	4	graphical	graphical	ADJ
fnp-5156	42	5	description	description	NOUN
fnp-5156	42	6	of	of	ADP
fnp-5156	42	7	the	the	DET
fnp-5156	42	8	study	study	NOUN
fnp-5156	42	9	groups	group	NOUN
fnp-5156	42	10	:	:	PUNCT
fnp-5156	42	11	of	of	ADP
fnp-5156	42	12	932	932	NUM
fnp-5156	42	13	tumors	tumor	NOUN
fnp-5156	42	14	receiving	receive	VERB
fnp-5156	42	15	a	a	DET
fnp-5156	42	16	classifier	classifier	NOUN
fnp-5156	42	17	prediction	prediction	NOUN
fnp-5156	42	18	(	(	PUNCT
fnp-5156	42	19	calibrated	calibrate	VERB
fnp-5156	42	20	score	score	NOUN
fnp-5156	42	21	>	>	PUNCT
fnp-5156	42	22	=	=	NOUN
fnp-5156	42	23	0.9	0.9	NUM
fnp-5156	42	24	)	)	PUNCT
fnp-5156	42	25	,	,	PUNCT
fnp-5156	42	26	767	767	NUM
fnp-5156	42	27	did	do	AUX
fnp-5156	42	28	not	not	PART
fnp-5156	42	29	receive	receive	VERB
fnp-5156	42	30	a	a	DET
fnp-5156	42	31	histological	histological	ADJ
fnp-5156	42	32	pxa	pxa	NOUN
fnp-5156	42	33	diagnosis	diagnosis	NOUN
fnp-5156	42	34	and	and	CCONJ
fnp-5156	42	35	the	the	DET
fnp-5156	42	36	latter	latter	ADJ
fnp-5156	42	37	were	be	AUX
fnp-5156	42	38	designated	designate	VERB
fnp-5156	42	39	as	as	ADP
fnp-5156	42	40	mcpxa	mcpxa	NOUN
fnp-5156	42	41	.	.	PUNCT
fnp-5156	43	1	165	165	NUM
fnp-5156	43	2	of	of	ADP
fnp-5156	43	3	the	the	DET
fnp-5156	43	4	932	932	NUM
fnp-5156	43	5	also	also	ADV
fnp-5156	43	6	were	be	AUX
fnp-5156	43	7	diagnosed	diagnose	VERB
fnp-5156	43	8	histologically	histologically	ADV
fnp-5156	43	9	as	as	ADP
fnp-5156	43	10	pxa	pxa	NOUN
fnp-5156	43	11	(	(	PUNCT
fnp-5156	43	12	or	or	CCONJ
fnp-5156	43	13	pxa	pxa	NOUN
fnp-5156	43	14	was	be	AUX
fnp-5156	43	15	in	in	ADP
fnp-5156	43	16	the	the	DET
fnp-5156	43	17	differential	differential	ADJ
fnp-5156	43	18	diagnosis	diagnosis	NOUN
fnp-5156	43	19	)	)	PUNCT
fnp-5156	43	20	and	and	CCONJ
fnp-5156	43	21	these	these	PRON
fnp-5156	43	22	were	be	AUX
fnp-5156	43	23	designated	designate	VERB
fnp-5156	43	24	as	as	ADP
fnp-5156	43	25	mcpxaref	mcpxaref	NOUN
fnp-5156	43	26	.	.	PUNCT
fnp-5156	44	1	a	a	DET
fnp-5156	44	2	control	control	NOUN
fnp-5156	44	3	group	group	NOUN
fnp-5156	44	4	containing	contain	VERB
fnp-5156	44	5	11	11	NUM
fnp-5156	44	6	mc	mc	NOUN
fnp-5156	44	7	with	with	ADP
fnp-5156	44	8	100	100	NUM
fnp-5156	44	9	tumors	tumor	NOUN
fnp-5156	44	10	each	each	PRON
fnp-5156	44	11	was	be	AUX
fnp-5156	44	12	selected	select	VERB
fnp-5156	44	13	based	base	VERB
fnp-5156	44	14	on	on	ADP
fnp-5156	44	15	the	the	DET
fnp-5156	44	16	most	most	ADV
fnp-5156	44	17	frequent	frequent	ADJ
fnp-5156	44	18	predictions	prediction	NOUN
fnp-5156	44	19	in	in	ADP
fnp-5156	44	20	tumors	tumor	NOUN
fnp-5156	44	21	histologically	histologically	ADV
fnp-5156	44	22	diagnosed	diagnose	VERB
fnp-5156	44	23	as	as	ADP
fnp-5156	44	24	pxa	pxa	NOUN
fnp-5156	44	25	but	but	CCONJ
fnp-5156	44	26	with	with	ADP
fnp-5156	44	27	other	other	ADJ
fnp-5156	44	28	classifier	classifier	NOUN
fnp-5156	44	29	predictions	prediction	NOUN
fnp-5156	44	30	.	.	PUNCT
fnp-5156	45	1	the	the	DET
fnp-5156	45	2	reference	reference	NOUN
fnp-5156	45	3	cohort	cohort	NOUN
fnp-5156	45	4	included	include	VERB
fnp-5156	45	5	:	:	PUNCT
fnp-5156	45	6	mc	mc	PROPN
fnp-5156	45	7	diffuse	diffuse	VERB
fnp-5156	45	8	paediatric	paediatric	ADJ
fnp-5156	45	9	-	-	PUNCT
fnp-5156	45	10	type	type	NOUN
fnp-5156	45	11	high	high	ADJ
fnp-5156	45	12	grade	grade	NOUN
fnp-5156	45	13	glioma	glioma	NOUN
fnp-5156	45	14	,	,	PUNCT
fnp-5156	45	15	rtk1	rtk1	NOUN
fnp-5156	45	16	subtype	subtype	NOUN
fnp-5156	45	17	,	,	PUNCT
fnp-5156	45	18	subclass	subclass	VERB
fnp-5156	45	19	a	a	DET
fnp-5156	45	20	(	(	PUNCT
fnp-5156	45	21	mcpedhgg_rtk1a	mcpedhgg_rtk1a	PROPN
fnp-5156	45	22	)	)	PUNCT
fnp-5156	45	23	;	;	PUNCT
fnp-5156	45	24	mc	mc	PROPN
fnp-5156	45	25	ganglioglioma	ganglioglioma	PROPN
fnp-5156	45	26	(	(	PUNCT
fnp-5156	45	27	mcgg	mcgg	NOUN
fnp-5156	45	28	)	)	PUNCT
fnp-5156	45	29	;	;	PUNCT
fnp-5156	45	30	mc	mc	PROPN
fnp-5156	45	31	glioblastoma	glioblastoma	NOUN
fnp-5156	45	32	,	,	PUNCT
fnp-5156	45	33	idh	idh	NOUN
fnp-5156	45	34	-	-	PUNCT
fnp-5156	45	35	wildtype	wildtype	NOUN
fnp-5156	45	36	,	,	PUNCT
fnp-5156	45	37	atypical	atypical	ADJ
fnp-5156	45	38	mesenchymal	mesenchymal	NOUN
fnp-5156	45	39	type	type	NOUN
fnp-5156	45	40	(	(	PUNCT
fnp-5156	45	41	mcgbm_mes_atyp	mcgbm_mes_atyp	NOUN
fnp-5156	45	42	)	)	PUNCT
fnp-5156	45	43	;	;	PUNCT
fnp-5156	45	44	mc	mc	PROPN
fnp-5156	45	45	glioblastoma	glioblastoma	NOUN
fnp-5156	45	46	,	,	PUNCT
fnp-5156	45	47	idh	idh	NOUN
fnp-5156	45	48	-	-	PUNCT
fnp-5156	45	49	wildtype	wildtype	NOUN
fnp-5156	45	50	,	,	PUNCT
fnp-5156	45	51	rtk1	rtk1	NOUN
fnp-5156	45	52	subtype	subtype	NOUN
fnp-5156	45	53	(	(	PUNCT
fnp-5156	45	54	mcgbm_rtk1	mcgbm_rtk1	PROPN
fnp-5156	45	55	)	)	PUNCT
fnp-5156	45	56	;	;	PUNCT
fnp-5156	45	57	mc	mc	PROPN
fnp-5156	45	58	glioblastoma	glioblastoma	NOUN
fnp-5156	45	59	,	,	PUNCT
fnp-5156	45	60	idh	idh	NOUN
fnp-5156	45	61	-	-	PUNCT
fnp-5156	45	62	wildtype	wildtype	NOUN
fnp-5156	45	63	,	,	PUNCT
fnp-5156	45	64	rtk2	rtk2	NOUN
fnp-5156	45	65	subtype	subtype	NOUN
fnp-5156	45	66	(	(	PUNCT
fnp-5156	45	67	mcgbm_rtk2	mcgbm_rtk2	NOUN
fnp-5156	45	68	)	)	PUNCT
fnp-5156	45	69	;	;	PUNCT
fnp-5156	45	70	mc	mc	PROPN
fnp-5156	45	71	glioblastoma	glioblastoma	NOUN
fnp-5156	45	72	,	,	PUNCT
fnp-5156	45	73	idh	idh	NOUN
fnp-5156	45	74	-	-	PUNCT
fnp-5156	45	75	wildtype	wildtype	NOUN
fnp-5156	45	76	,	,	PUNCT
fnp-5156	45	77	typical	typical	ADJ
fnp-5156	45	78	mesenchymal	mesenchymal	ADJ
fnp-5156	45	79	type	type	NOUN
fnp-5156	45	80	(	(	PUNCT
fnp-5156	45	81	mcgbm_mes_typ	mcgbm_mes_typ	NOUN
fnp-5156	45	82	)	)	PUNCT
fnp-5156	45	83	;	;	PUNCT
fnp-5156	45	84	mc	mc	PROPN
fnp-5156	45	85	high	high	ADJ
fnp-5156	45	86	-	-	PUNCT
fnp-5156	45	87	grade	grade	NOUN
fnp-5156	45	88	astrocytoma	astrocytoma	NOUN
fnp-5156	45	89	with	with	ADP
fnp-5156	45	90	piloid	piloid	PROPN
fnp-5156	45	91	features	feature	NOUN
fnp-5156	45	92	(	(	PUNCT
fnp-5156	45	93	mchgap	mchgap	PROPN
fnp-5156	45	94	)	)	PUNCT
fnp-5156	45	95	;	;	PUNCT
fnp-5156	45	96	mc	mc	PROPN
fnp-5156	45	97	infant	infant	NOUN
fnp-5156	45	98	-	-	PUNCT
fnp-5156	45	99	type	type	NOUN
fnp-5156	45	100	hemispheric	hemispheric	ADJ
fnp-5156	45	101	glioma	glioma	NOUN
fnp-5156	45	102	(	(	PUNCT
fnp-5156	45	103	mcihg	mcihg	NOUN
fnp-5156	45	104	)	)	PUNCT
fnp-5156	45	105	;	;	PUNCT
fnp-5156	45	106	mc	mc	PROPN
fnp-5156	45	107	infratentorial	infratentorial	PROPN
fnp-5156	45	108	pilocytic	pilocytic	ADJ
fnp-5156	45	109	astrocytoma	astrocytoma	NOUN
fnp-5156	45	110	(	(	PUNCT
fnp-5156	45	111	mcpa_inf	mcpa_inf	NUM
fnp-5156	45	112	)	)	PUNCT
fnp-5156	45	113	;	;	PUNCT
fnp-5156	45	114	mc	mc	PROPN
fnp-5156	45	115	neuroepithelial	neuroepithelial	ADJ
fnp-5156	45	116	tumour	tumour	NOUN
fnp-5156	45	117	with	with	ADP
fnp-5156	45	118	patz1	patz1	NOUN
fnp-5156	45	119	fusion	fusion	NOUN
fnp-5156	45	120	(	(	PUNCT
fnp-5156	45	121	mcnet_patz1	mcnet_patz1	NOUN
fnp-5156	45	122	)	)	PUNCT
fnp-5156	45	123	and	and	CCONJ
fnp-5156	45	124	mc	mc	PROPN
fnp-5156	45	125	supratentorial	supratentorial	ADJ
fnp-5156	45	126	pilocytic	pilocytic	ADJ
fnp-5156	45	127	astrocytoma	astrocytoma	NOUN
fnp-5156	45	128	(	(	PUNCT
fnp-5156	45	129	mcpa_cort	mcpa_cort	NOUN
fnp-5156	45	130	)	)	PUNCT
fnp-5156	45	131	.	.	PUNCT
fnp-5156	46	1	determination	determination	NOUN
fnp-5156	46	2	of	of	ADP
fnp-5156	46	3	cnv	cnv	PROPN
fnp-5156	46	4	and	and	CCONJ
fnp-5156	46	5	summary	summary	NOUN
fnp-5156	46	6	cnv	cnv	PROPN
fnp-5156	46	7	plots	plot	NOUN
fnp-5156	46	8	tsne	tsne	NOUN
fnp-5156	46	9	analyses	analysis	NOUN
fnp-5156	46	10	were	be	AUX
fnp-5156	46	11	performed	perform	VERB
fnp-5156	46	12	using	use	VERB
fnp-5156	46	13	the	the	DET
fnp-5156	46	14	r	r	NOUN
fnp-5156	46	15	-	-	PUNCT
fnp-5156	46	16	package	package	NOUN
fnp-5156	46	17	rtsne	rtsne	NOUN
fnp-5156	46	18	(	(	PUNCT
fnp-5156	46	19	https://github.com/jkrijthe/rtsne	https://github.com/jkrijthe/rtsne	NOUN
fnp-5156	46	20	)	)	PUNCT
fnp-5156	46	21	employing	employ	VERB
fnp-5156	46	22	the	the	DET
fnp-5156	46	23	20,000	20,000	NUM
fnp-5156	46	24	most	most	ADV
fnp-5156	46	25	variable	variable	ADJ
fnp-5156	46	26	cpg	cpg	NOUN
fnp-5156	46	27	sites	site	NOUN
fnp-5156	46	28	according	accord	VERB
fnp-5156	46	29	to	to	ADP
fnp-5156	46	30	standard	standard	ADJ
fnp-5156	46	31	deviation	deviation	NOUN
fnp-5156	46	32	;	;	PUNCT
fnp-5156	46	33	3000	3000	NUM
fnp-5156	46	34	iterations	iteration	NOUN
fnp-5156	46	35	and	and	CCONJ
fnp-5156	46	36	a	a	DET
fnp-5156	46	37	perplexity	perplexity	NOUN
fnp-5156	46	38	value	value	NOUN
fnp-5156	46	39	of	of	ADP
fnp-5156	46	40	10	10	NUM
fnp-5156	46	41	.	.	PUNCT
fnp-5156	47	1	cnv	cnv	PROPN
fnp-5156	47	2	data	datum	NOUN
fnp-5156	47	3	were	be	AUX
fnp-5156	47	4	calculated	calculate	VERB
fnp-5156	47	5	from	from	ADP
fnp-5156	47	6	the	the	DET
fnp-5156	47	7	output	output	NOUN
fnp-5156	47	8	of	of	ADP
fnp-5156	47	9	the	the	DET
fnp-5156	47	10	illumina	illumina	PROPN
fnp-5156	47	11	450k	450k	PROPN
fnp-5156	47	12	or	or	CCONJ
fnp-5156	47	13	850k	850k	NOUN
fnp-5156	47	14	/	/	SYM
fnp-5156	47	15	epic	epic	ADJ
fnp-5156	47	16	platforms	platform	NOUN
fnp-5156	47	17	.	.	PUNCT
fnp-5156	48	1	cnv	cnv	NOUN
fnp-5156	48	2	plots	plot	NOUN
fnp-5156	48	3	are	be	AUX
fnp-5156	48	4	based	base	VERB
fnp-5156	48	5	on	on	ADP
fnp-5156	48	6	the	the	DET
fnp-5156	48	7	raw	raw	ADJ
fnp-5156	48	8	data	datum	NOUN
fnp-5156	48	9	subjected	subject	VERB
fnp-5156	48	10	to	to	ADP
fnp-5156	48	11	analysis	analysis	NOUN
fnp-5156	48	12	by	by	ADP
fnp-5156	48	13	the	the	DET
fnp-5156	48	14	‘	'	PUNCT
fnp-5156	48	15	conumee	conumee	ADJ
fnp-5156	48	16	’	'	PUNCT
fnp-5156	48	17	r	r	NOUN
fnp-5156	48	18	package	package	NOUN
fnp-5156	48	19	in	in	ADP
fnp-5156	48	20	bioconductor	bioconductor	NOUN
fnp-5156	48	21	(	(	PUNCT
fnp-5156	48	22	https://www.bioconductor.org/packages/release/bioc/html/conumee.html	https://www.bioconductor.org/packages/release/bioc/html/conumee.html	PROPN
fnp-5156	48	23	)	)	PUNCT
fnp-5156	48	24	.	.	PUNCT
fnp-5156	49	1	assessment	assessment	NOUN
fnp-5156	49	2	of	of	ADP
fnp-5156	49	3	copy	copy	NOUN
fnp-5156	49	4	-	-	PUNCT
fnp-5156	49	5	number	number	NOUN
fnp-5156	49	6	alterations	alteration	NOUN
fnp-5156	49	7	was	be	AUX
fnp-5156	49	8	automated	automate	VERB
fnp-5156	49	9	using	use	VERB
fnp-5156	49	10	the	the	DET
fnp-5156	49	11	results	result	NOUN
fnp-5156	49	12	from	from	ADP
fnp-5156	49	13	conumee	conumee	NOUN
fnp-5156	49	14	after	after	ADP
fnp-5156	49	15	additional	additional	ADJ
fnp-5156	49	16	baseline	baseline	ADJ
fnp-5156	49	17	correction	correction	NOUN
fnp-5156	49	18	.	.	PUNCT
fnp-5156	50	1	amplifications	amplification	NOUN
fnp-5156	50	2	were	be	AUX
fnp-5156	50	3	called	call	VERB
fnp-5156	50	4	if	if	SCONJ
fnp-5156	50	5	the	the	DET
fnp-5156	50	6	respective	respective	ADJ
fnp-5156	50	7	probes	probe	NOUN
fnp-5156	50	8	exhibited	exhibit	VERB
fnp-5156	50	9	a	a	DET
fnp-5156	50	10	value	value	NOUN
fnp-5156	50	11	higher	high	ADJ
fnp-5156	50	12	than	than	ADP
fnp-5156	50	13	0,55	0,55	PRON
fnp-5156	50	14	on	on	ADP
fnp-5156	50	15	a	a	DET
fnp-5156	50	16	log2	log2	NOUN
fnp-5156	50	17	-	-	PUNCT
fnp-5156	50	18	scale	scale	NOUN
fnp-5156	50	19	.	.	PUNCT
fnp-5156	51	1	homozygous	homozygous	ADJ
fnp-5156	51	2	deletions	deletion	NOUN
fnp-5156	51	3	were	be	AUX
fnp-5156	51	4	called	call	VERB
fnp-5156	51	5	if	if	SCONJ
fnp-5156	51	6	the	the	DET
fnp-5156	51	7	respective	respective	ADJ
fnp-5156	51	8	probes	probe	NOUN
fnp-5156	51	9	exhibited	exhibit	VERB
fnp-5156	51	10	a	a	DET
fnp-5156	51	11	value	value	NOUN
fnp-5156	51	12	lower	low	ADJ
fnp-5156	51	13	than	than	ADP
fnp-5156	51	14	-0.4	-0.4	NUM
fnp-5156	51	15	on	on	ADP
fnp-5156	51	16	a	a	DET
fnp-5156	51	17	log2	log2	NOUN
fnp-5156	51	18	-	-	PUNCT
fnp-5156	51	19	scale	scale	NOUN
fnp-5156	51	20	.	.	PUNCT
fnp-5156	52	1	statistics	statistic	NOUN
fnp-5156	52	2	all	all	DET
fnp-5156	52	3	data	datum	NOUN
fnp-5156	52	4	sets	set	NOUN
fnp-5156	52	5	were	be	AUX
fnp-5156	52	6	collected	collect	VERB
fnp-5156	52	7	retrospectively	retrospectively	ADV
fnp-5156	52	8	.	.	PUNCT
fnp-5156	53	1	distribution	distribution	NOUN
fnp-5156	53	2	of	of	ADP
fnp-5156	53	3	nominal	nominal	ADJ
fnp-5156	53	4	data	datum	NOUN
fnp-5156	53	5	was	be	AUX
fnp-5156	53	6	tested	test	VERB
fnp-5156	53	7	employing	employ	VERB
fnp-5156	53	8	fisher	fisher	PROPN
fnp-5156	53	9	’s	’s	PART
fnp-5156	53	10	exact	exact	ADJ
fnp-5156	53	11	test	test	NOUN
fnp-5156	53	12	.	.	PUNCT
fnp-5156	54	1	results	result	NOUN
fnp-5156	54	2	diagnoses	diagnosis	NOUN
fnp-5156	54	3	in	in	ADP
fnp-5156	54	4	mcpxa	mcpxa	NOUN
fnp-5156	54	5	tumors	tumor	NOUN
fnp-5156	54	6	with	with	ADP
fnp-5156	54	7	a	a	DET
fnp-5156	54	8	mcpxa	mcpxa	NOUN
fnp-5156	54	9	prediction	prediction	NOUN
fnp-5156	54	10	but	but	CCONJ
fnp-5156	54	11	without	without	ADP
fnp-5156	54	12	a	a	DET
fnp-5156	54	13	pxa	pxa	NOUN
fnp-5156	54	14	diagnosis	diagnosis	NOUN
fnp-5156	54	15	(	(	PUNCT
fnp-5156	54	16	n=767	n=767	NOUN
fnp-5156	54	17	)	)	PUNCT
fnp-5156	54	18	received	receive	VERB
fnp-5156	54	19	another	another	DET
fnp-5156	54	20	diagnosis	diagnosis	NOUN
fnp-5156	54	21	in	in	ADP
fnp-5156	54	22	399	399	NUM
fnp-5156	54	23	instances	instance	NOUN
fnp-5156	54	24	.	.	PUNCT
fnp-5156	55	1	no	no	DET
fnp-5156	55	2	diagnosis	diagnosis	NOUN
fnp-5156	55	3	was	be	AUX
fnp-5156	55	4	provided	provide	VERB
fnp-5156	55	5	for	for	ADP
fnp-5156	55	6	368	368	NUM
fnp-5156	55	7	cases	case	NOUN
fnp-5156	55	8	.	.	PUNCT
fnp-5156	56	1	diagnoses	diagnosis	NOUN
fnp-5156	56	2	were	be	AUX
fnp-5156	56	3	slightly	slightly	ADV
fnp-5156	56	4	simplified	simplified	ADJ
fnp-5156	56	5	to	to	PART
fnp-5156	56	6	allow	allow	VERB
fnp-5156	56	7	for	for	ADP
fnp-5156	56	8	categorization	categorization	NOUN
fnp-5156	56	9	.	.	PUNCT
fnp-5156	57	1	a	a	DET
fnp-5156	57	2	list	list	NOUN
fnp-5156	57	3	of	of	ADP
fnp-5156	57	4	given	give	VERB
fnp-5156	57	5	diagnoses	diagnosis	NOUN
fnp-5156	57	6	is	be	AUX
fnp-5156	57	7	provided	provide	VERB
fnp-5156	57	8	in	in	ADP
fnp-5156	57	9	supplementary	supplementary	ADJ
fnp-5156	57	10	table	table	NOUN
fnp-5156	57	11	2	2	NUM
fnp-5156	57	12	.	.	NOUN
fnp-5156	57	13	tsne	tsne	NOUN
fnp-5156	57	14	of	of	ADP
fnp-5156	57	15	mc	mc	PROPN
fnp-5156	57	16	pxa	pxa	PROPN
fnp-5156	57	17	,	,	PUNCT
fnp-5156	57	18	mcpxaref	mcpxaref	NOUN
fnp-5156	57	19	,	,	PUNCT
fnp-5156	57	20	and	and	CCONJ
fnp-5156	57	21	reference	reference	NOUN
fnp-5156	57	22	sets	set	NOUN
fnp-5156	57	23	using	use	VERB
fnp-5156	57	24	t	t	NOUN
fnp-5156	57	25	-	-	PUNCT
fnp-5156	57	26	distributed	distribute	VERB
fnp-5156	57	27	stochastic	stochastic	ADJ
fnp-5156	57	28	neighbor	neighbor	NOUN
fnp-5156	57	29	embedding	embed	VERB
fnp-5156	57	30	(	(	PUNCT
fnp-5156	57	31	t	t	PROPN
fnp-5156	57	32	-	-	PUNCT
fnp-5156	57	33	sne	sne	NOUN
fnp-5156	57	34	)	)	PUNCT
fnp-5156	57	35	we	we	PRON
fnp-5156	57	36	analyzed	analyze	VERB
fnp-5156	57	37	all	all	DET
fnp-5156	57	38	tumors	tumor	NOUN
fnp-5156	57	39	of	of	ADP
fnp-5156	57	40	the	the	DET
fnp-5156	57	41	study	study	NOUN
fnp-5156	57	42	cohort	cohort	NOUN
fnp-5156	57	43	and	and	CCONJ
fnp-5156	57	44	reference	reference	NOUN
fnp-5156	57	45	sets	set	NOUN
fnp-5156	57	46	(	(	PUNCT
fnp-5156	57	47	figure	figure	NOUN
fnp-5156	57	48	2	2	NUM
fnp-5156	57	49	)	)	PUNCT
fnp-5156	57	50	.	.	PUNCT
fnp-5156	58	1	tumors	tumor	NOUN
fnp-5156	58	2	receiving	receive	VERB
fnp-5156	58	3	the	the	DET
fnp-5156	58	4	classifier	classifier	NOUN
fnp-5156	58	5	prediction	prediction	NOUN
fnp-5156	58	6	mcpxa	mcpxa	NOUN
fnp-5156	58	7	were	be	AUX
fnp-5156	58	8	annotated	annotate	VERB
fnp-5156	58	9	according	accord	VERB
fnp-5156	58	10	to	to	ADP
fnp-5156	58	11	presence	presence	NOUN
fnp-5156	58	12	(	(	PUNCT
fnp-5156	58	13	mcpxaref	mcpxaref	NOUN
fnp-5156	58	14	)	)	PUNCT
fnp-5156	58	15	or	or	CCONJ
fnp-5156	58	16	absence	absence	NOUN
fnp-5156	58	17	(	(	PUNCT
fnp-5156	58	18	mcpxa	mcpxa	NOUN
fnp-5156	58	19	)	)	PUNCT
fnp-5156	58	20	of	of	ADP
fnp-5156	58	21	the	the	DET
fnp-5156	58	22	histological	histological	ADJ
fnp-5156	58	23	diagnosis	diagnosis	NOUN
fnp-5156	58	24	(	(	PUNCT
fnp-5156	58	25	or	or	CCONJ
fnp-5156	58	26	differential	differential	ADJ
fnp-5156	58	27	diagnosis	diagnosis	NOUN
fnp-5156	58	28	)	)	PUNCT
fnp-5156	58	29	of	of	ADP
fnp-5156	58	30	pxa	pxa	NOUN
fnp-5156	58	31	.	.	PUNCT
fnp-5156	59	1	importantly	importantly	ADV
fnp-5156	59	2	,	,	PUNCT
fnp-5156	59	3	the	the	DET
fnp-5156	59	4	distribution	distribution	NOUN
fnp-5156	59	5	within	within	ADP
fnp-5156	59	6	mcpxa	mcpxa	NOUN
fnp-5156	59	7	and	and	CCONJ
fnp-5156	59	8	mcpxaref	mcpxaref	NOUN
fnp-5156	59	9	is	be	AUX
fnp-5156	59	10	similar	similar	ADJ
fnp-5156	59	11	.	.	PUNCT
fnp-5156	60	1	this	this	PRON
fnp-5156	60	2	demonstrates	demonstrate	VERB
fnp-5156	60	3	that	that	SCONJ
fnp-5156	60	4	the	the	DET
fnp-5156	60	5	morphological	morphological	ADJ
fnp-5156	60	6	features	feature	NOUN
fnp-5156	60	7	defining	define	VERB
fnp-5156	60	8	histological	histological	ADJ
fnp-5156	60	9	pxa	pxa	NOUN
fnp-5156	60	10	can	can	AUX
fnp-5156	60	11	not	not	PART
fnp-5156	60	12	readily	readily	ADV
fnp-5156	60	13	single	single	VERB
fnp-5156	60	14	out	out	ADP
fnp-5156	60	15	a	a	DET
fnp-5156	60	16	subpopulation	subpopulation	NOUN
fnp-5156	60	17	within	within	ADP
fnp-5156	60	18	mcpxa	mcpxa	NOUN
fnp-5156	60	19	associated	associate	VERB
fnp-5156	60	20	with	with	ADP
fnp-5156	60	21	‘	'	PUNCT
fnp-5156	60	22	canonical	canonical	ADJ
fnp-5156	60	23	’	'	PUNCT
fnp-5156	60	24	features	feature	NOUN
fnp-5156	60	25	.	.	PUNCT
fnp-5156	61	1	figure	figure	VERB
fnp-5156	61	2	2	2	NUM
fnp-5156	61	3	:	:	PUNCT
fnp-5156	61	4	tsne	tsne	VERB
fnp-5156	61	5	analysis	analysis	NOUN
fnp-5156	61	6	of	of	ADP
fnp-5156	61	7	mcpxa	mcpxa	NOUN
fnp-5156	61	8	,	,	PUNCT
fnp-5156	61	9	mcpxaref	mcpxaref	ADJ
fnp-5156	61	10	and	and	CCONJ
fnp-5156	61	11	reference	reference	NOUN
fnp-5156	61	12	sets	set	NOUN
fnp-5156	61	13	.	.	PUNCT
fnp-5156	62	1	tumors	tumor	NOUN
fnp-5156	62	2	from	from	ADP
fnp-5156	62	3	the	the	DET
fnp-5156	62	4	mcpxa	mcpxa	NOUN
fnp-5156	62	5	and	and	CCONJ
fnp-5156	62	6	the	the	DET
fnp-5156	62	7	mcpxaref	mcpxaref	ADJ
fnp-5156	62	8	cohorts	cohort	NOUN
fnp-5156	62	9	cluster	cluster	NOUN
fnp-5156	62	10	together	together	ADV
fnp-5156	62	11	and	and	CCONJ
fnp-5156	62	12	are	be	AUX
fnp-5156	62	13	separated	separate	VERB
fnp-5156	62	14	from	from	ADP
fnp-5156	62	15	the	the	DET
fnp-5156	62	16	reference	reference	NOUN
fnp-5156	62	17	sets	set	NOUN
fnp-5156	62	18	.	.	PUNCT
fnp-5156	63	1	parameters	parameter	NOUN
fnp-5156	63	2	:	:	PUNCT
fnp-5156	63	3	tsne_cpgs_20000_perplexities_10_iter_3000_theta_0_eta_200_dim_2	tsne_cpgs_20000_perplexities_10_iter_3000_theta_0_eta_200_dim_2	ADJ
fnp-5156	63	4	summary	summary	NOUN
fnp-5156	63	5	cnv	cnv	PROPN
fnp-5156	63	6	(	(	PUNCT
fnp-5156	63	7	sumcnv	sumcnv	NOUN
fnp-5156	63	8	)	)	PUNCT
fnp-5156	63	9	plots	plot	NOUN
fnp-5156	63	10	of	of	ADP
fnp-5156	63	11	mcpxa	mcpxa	NOUN
fnp-5156	63	12	,	,	PUNCT
fnp-5156	63	13	mcpxaref	mcpxaref	ADJ
fnp-5156	63	14	and	and	CCONJ
fnp-5156	63	15	reference	reference	NOUN
fnp-5156	63	16	sets	set	NOUN
fnp-5156	63	17	for	for	ADP
fnp-5156	63	18	an	an	DET
fnp-5156	63	19	overview	overview	NOUN
fnp-5156	63	20	,	,	PUNCT
fnp-5156	63	21	summary	summary	NOUN
fnp-5156	63	22	cnv	cnv	PROPN
fnp-5156	63	23	(	(	PUNCT
fnp-5156	63	24	sumcnv	sumcnv	NOUN
fnp-5156	63	25	)	)	PUNCT
fnp-5156	63	26	plots	plot	NOUN
fnp-5156	63	27	were	be	AUX
fnp-5156	63	28	generated	generate	VERB
fnp-5156	63	29	for	for	ADP
fnp-5156	63	30	all	all	DET
fnp-5156	63	31	cohorts	cohort	NOUN
fnp-5156	63	32	.	.	PUNCT
fnp-5156	64	1	tumors	tumor	NOUN
fnp-5156	64	2	with	with	ADP
fnp-5156	64	3	the	the	DET
fnp-5156	64	4	classifier	classifier	NOUN
fnp-5156	64	5	prediction	prediction	NOUN
fnp-5156	64	6	pxa	pxa	NOUN
fnp-5156	64	7	were	be	AUX
fnp-5156	64	8	divided	divide	VERB
fnp-5156	64	9	in	in	ADP
fnp-5156	64	10	two	two	NUM
fnp-5156	64	11	subgroups	subgroup	NOUN
fnp-5156	64	12	,	,	PUNCT
fnp-5156	64	13	depending	depend	VERB
fnp-5156	64	14	on	on	ADP
fnp-5156	64	15	whether	whether	SCONJ
fnp-5156	64	16	the	the	DET
fnp-5156	64	17	histological	histological	ADJ
fnp-5156	64	18	(	(	PUNCT
fnp-5156	64	19	differential	differential	ADJ
fnp-5156	64	20	)	)	PUNCT
fnp-5156	64	21	diagnosis	diagnosis	NOUN
fnp-5156	64	22	was	be	AUX
fnp-5156	64	23	pxa	pxa	NOUN
fnp-5156	64	24	(	(	PUNCT
fnp-5156	64	25	mcpxaref	mcpxaref	ADJ
fnp-5156	64	26	,	,	PUNCT
fnp-5156	64	27	n=165	n=165	NUM
fnp-5156	64	28	)	)	PUNCT
fnp-5156	64	29	or	or	CCONJ
fnp-5156	64	30	another	another	DET
fnp-5156	64	31	histological	histological	ADJ
fnp-5156	64	32	diagnosis	diagnosis	NOUN
fnp-5156	64	33	or	or	CCONJ
fnp-5156	64	34	no	no	DET
fnp-5156	64	35	diagnosis	diagnosis	NOUN
fnp-5156	64	36	was	be	AUX
fnp-5156	64	37	given	give	VERB
fnp-5156	64	38	(	(	PUNCT
fnp-5156	64	39	mcpxa	mcpxa	NOUN
fnp-5156	64	40	,	,	PUNCT
fnp-5156	64	41	n=767	n=767	PROPN
fnp-5156	64	42	)	)	PUNCT
fnp-5156	64	43	.	.	PUNCT
fnp-5156	65	1	sumcnv	sumcnv	NOUN
fnp-5156	65	2	plots	plot	NOUN
fnp-5156	65	3	of	of	ADP
fnp-5156	65	4	mcpxaref	mcpxaref	NOUN
fnp-5156	65	5	and	and	CCONJ
fnp-5156	65	6	mcpxa	mcpxa	NOUN
fnp-5156	65	7	were	be	AUX
fnp-5156	65	8	virtually	virtually	ADV
fnp-5156	65	9	identical	identical	ADJ
fnp-5156	65	10	,	,	PUNCT
fnp-5156	65	11	indicating	indicate	VERB
fnp-5156	65	12	that	that	SCONJ
fnp-5156	65	13	the	the	DET
fnp-5156	65	14	presence	presence	NOUN
fnp-5156	65	15	or	or	CCONJ
fnp-5156	65	16	absence	absence	NOUN
fnp-5156	65	17	of	of	ADP
fnp-5156	65	18	the	the	DET
fnp-5156	65	19	histological	histological	ADJ
fnp-5156	65	20	diagnosis	diagnosis	NOUN
fnp-5156	65	21	pxa	pxa	NOUN
fnp-5156	65	22	does	do	AUX
fnp-5156	65	23	not	not	PART
fnp-5156	65	24	associate	associate	VERB
fnp-5156	65	25	with	with	ADP
fnp-5156	65	26	the	the	DET
fnp-5156	65	27	frequency	frequency	NOUN
fnp-5156	65	28	of	of	ADP
fnp-5156	65	29	any	any	DET
fnp-5156	65	30	cnv	cnv	NOUN
fnp-5156	65	31	(	(	PUNCT
fnp-5156	65	32	figure	figure	NOUN
fnp-5156	65	33	3	3	NUM
fnp-5156	65	34	)	)	PUNCT
fnp-5156	65	35	.	.	PUNCT
fnp-5156	66	1	the	the	DET
fnp-5156	66	2	sumcnv	sumcnv	NOUN
fnp-5156	66	3	profiles	profile	NOUN
fnp-5156	66	4	of	of	ADP
fnp-5156	66	5	the	the	DET
fnp-5156	66	6	11	11	NUM
fnp-5156	66	7	reference	reference	NOUN
fnp-5156	66	8	sets	set	NOUN
fnp-5156	66	9	of	of	ADP
fnp-5156	66	10	differential	differential	ADJ
fnp-5156	66	11	diagnoses	diagnosis	NOUN
fnp-5156	66	12	were	be	AUX
fnp-5156	66	13	clearly	clearly	ADV
fnp-5156	66	14	distinct	distinct	ADJ
fnp-5156	66	15	from	from	ADP
fnp-5156	66	16	the	the	DET
fnp-5156	66	17	mcpxa	mcpxa	NOUN
fnp-5156	66	18	and	and	CCONJ
fnp-5156	66	19	mcpxaref	mcpxaref	ADJ
fnp-5156	66	20	sumcnv	sumcnv	NOUN
fnp-5156	66	21	profiles	profile	NOUN
fnp-5156	66	22	.	.	PUNCT
fnp-5156	67	1	notable	notable	ADJ
fnp-5156	67	2	differences	difference	NOUN
fnp-5156	67	3	can	can	AUX
fnp-5156	67	4	be	be	AUX
fnp-5156	67	5	observed	observe	VERB
fnp-5156	67	6	between	between	ADP
fnp-5156	67	7	the	the	DET
fnp-5156	67	8	4	4	NUM
fnp-5156	67	9	glioblastoma	glioblastoma	NOUN
fnp-5156	67	10	idh	idh	NOUN
fnp-5156	67	11	wildtype	wildtype	NOUN
fnp-5156	67	12	subgroups	subgroup	NOUN
fnp-5156	67	13	containing	contain	VERB
fnp-5156	67	14	100	100	NUM
fnp-5156	67	15	samples	sample	NOUN
fnp-5156	67	16	each	each	PRON
fnp-5156	67	17	.	.	PUNCT
fnp-5156	68	1	most	most	ADV
fnp-5156	68	2	evident	evident	ADJ
fnp-5156	68	3	was	be	AUX
fnp-5156	68	4	the	the	DET
fnp-5156	68	5	highest	high	ADJ
fnp-5156	68	6	proportion	proportion	NOUN
fnp-5156	68	7	of	of	ADP
fnp-5156	68	8	the	the	DET
fnp-5156	68	9	7/10	7/10	NUM
fnp-5156	68	10	signature	signature	NOUN
fnp-5156	68	11	and	and	CCONJ
fnp-5156	68	12	an	an	DET
fnp-5156	68	13	increased	increase	VERB
fnp-5156	68	14	incidence	incidence	NOUN
fnp-5156	68	15	of	of	ADP
fnp-5156	68	16	trisomies	trisomy	NOUN
fnp-5156	68	17	of	of	ADP
fnp-5156	68	18	chromosomes	chromosome	NOUN
fnp-5156	68	19	19	19	NUM
fnp-5156	68	20	and	and	CCONJ
fnp-5156	68	21	20	20	NUM
fnp-5156	68	22	in	in	ADP
fnp-5156	68	23	gbm	gbm	PROPN
fnp-5156	68	24	idh	idh	PROPN
fnp-5156	68	25	wildtype	wildtype	PROPN
fnp-5156	68	26	rtk2	rtk2	NOUN
fnp-5156	68	27	.	.	PUNCT
fnp-5156	69	1	these	these	DET
fnp-5156	69	2	differences	difference	NOUN
fnp-5156	69	3	will	will	AUX
fnp-5156	69	4	be	be	AUX
fnp-5156	69	5	followed	follow	VERB
fnp-5156	69	6	up	up	ADP
fnp-5156	69	7	in	in	ADP
fnp-5156	69	8	larger	large	ADJ
fnp-5156	69	9	cohorts	cohort	NOUN
fnp-5156	69	10	.	.	PUNCT
fnp-5156	70	1	summary	summary	NOUN
fnp-5156	70	2	cnv	cnv	PROPN
fnp-5156	70	3	profiles	profile	NOUN
fnp-5156	70	4	are	be	AUX
fnp-5156	70	5	provided	provide	VERB
fnp-5156	70	6	in	in	ADP
fnp-5156	70	7	figure	figure	NOUN
fnp-5156	70	8	3	3	NUM
fnp-5156	70	9	.	.	PUNCT
fnp-5156	70	10	figure	figure	VERB
fnp-5156	70	11	3	3	NUM
fnp-5156	70	12	:	:	PUNCT
fnp-5156	70	13	summary	summary	NOUN
fnp-5156	70	14	cnv	cnv	PROPN
fnp-5156	70	15	plots	plot	NOUN
fnp-5156	70	16	of	of	ADP
fnp-5156	70	17	mcpxa	mcpxa	NOUN
fnp-5156	70	18	,	,	PUNCT
fnp-5156	70	19	mcpxaref	mcpxaref	ADJ
fnp-5156	70	20	and	and	CCONJ
fnp-5156	70	21	reference	reference	NOUN
fnp-5156	70	22	sets	set	NOUN
fnp-5156	70	23	.	.	PUNCT
fnp-5156	71	1	prevalence	prevalence	NOUN
fnp-5156	71	2	of	of	ADP
fnp-5156	71	3	the	the	DET
fnp-5156	71	4	7/10	7/10	NUM
fnp-5156	71	5	signature	signature	NOUN
fnp-5156	71	6	in	in	ADP
fnp-5156	71	7	mcpxa	mcpxa	NOUN
fnp-5156	71	8	,	,	PUNCT
fnp-5156	71	9	mcpxaref	mcpxaref	ADJ
fnp-5156	71	10	and	and	CCONJ
fnp-5156	71	11	reference	reference	NOUN
fnp-5156	71	12	sets	set	VERB
fnp-5156	71	13	combined	combine	VERB
fnp-5156	71	14	gain	gain	NOUN
fnp-5156	71	15	of	of	ADP
fnp-5156	71	16	chromosome	chromosome	NOUN
fnp-5156	71	17	7	7	NUM
fnp-5156	71	18	and	and	CCONJ
fnp-5156	71	19	loss	loss	NOUN
fnp-5156	71	20	of	of	ADP
fnp-5156	71	21	chromosome	chromosome	NOUN
fnp-5156	71	22	10	10	NUM
fnp-5156	71	23	,	,	PUNCT
fnp-5156	71	24	dubbed	dub	VERB
fnp-5156	71	25	7/10	7/10	NUM
fnp-5156	71	26	signature	signature	NOUN
fnp-5156	71	27	,	,	PUNCT
fnp-5156	71	28	is	be	AUX
fnp-5156	71	29	a	a	DET
fnp-5156	71	30	very	very	ADV
fnp-5156	71	31	frequent	frequent	ADJ
fnp-5156	71	32	molecular	molecular	ADJ
fnp-5156	71	33	feature	feature	NOUN
fnp-5156	71	34	of	of	ADP
fnp-5156	71	35	glioblastoma	glioblastoma	NOUN
fnp-5156	71	36	.	.	PUNCT
fnp-5156	72	1	the	the	DET
fnp-5156	72	2	best	good	ADJ
fnp-5156	72	3	parameters	parameter	NOUN
fnp-5156	72	4	for	for	ADP
fnp-5156	72	5	defining	define	VERB
fnp-5156	72	6	the	the	DET
fnp-5156	72	7	7/10	7/10	NUM
fnp-5156	72	8	signature	signature	NOUN
fnp-5156	72	9	have	have	AUX
fnp-5156	72	10	not	not	PART
fnp-5156	72	11	yet	yet	ADV
fnp-5156	72	12	been	be	AUX
fnp-5156	72	13	established	establish	VERB
fnp-5156	72	14	.	.	PUNCT
fnp-5156	73	1	in	in	ADP
fnp-5156	73	2	this	this	DET
fnp-5156	73	3	study	study	NOUN
fnp-5156	73	4	,	,	PUNCT
fnp-5156	73	5	a	a	DET
fnp-5156	73	6	previously	previously	ADV
fnp-5156	73	7	published	publish	VERB
fnp-5156	73	8	algorithm	algorithm	NOUN
fnp-5156	73	9	has	have	AUX
fnp-5156	73	10	been	be	AUX
fnp-5156	73	11	employed	employ	VERB
fnp-5156	73	12	(	(	PUNCT
fnp-5156	73	13	9	9	NUM
fnp-5156	73	14	)	)	PUNCT
fnp-5156	73	15	.	.	PUNCT
fnp-5156	74	1	presence	presence	NOUN
fnp-5156	74	2	of	of	ADP
fnp-5156	74	3	the	the	DET
fnp-5156	74	4	7/10	7/10	NUM
fnp-5156	74	5	signature	signature	NOUN
fnp-5156	74	6	was	be	AUX
fnp-5156	74	7	scored	score	VERB
fnp-5156	74	8	if	if	SCONJ
fnp-5156	74	9	gain	gain	NOUN
fnp-5156	74	10	of	of	ADP
fnp-5156	74	11	at	at	ADV
fnp-5156	74	12	least	least	ADV
fnp-5156	74	13	50	50	NUM
fnp-5156	74	14	%	%	NOUN
fnp-5156	74	15	of	of	ADP
fnp-5156	74	16	the	the	DET
fnp-5156	74	17	short	short	ADJ
fnp-5156	74	18	or	or	CCONJ
fnp-5156	74	19	the	the	DET
fnp-5156	74	20	long	long	ADJ
fnp-5156	74	21	arm	arm	NOUN
fnp-5156	74	22	of	of	ADP
fnp-5156	74	23	chromosome	chromosome	NOUN
fnp-5156	74	24	7	7	NUM
fnp-5156	74	25	coincided	coincide	VERB
fnp-5156	74	26	with	with	ADP
fnp-5156	74	27	loss	loss	NOUN
fnp-5156	74	28	of	of	ADP
fnp-5156	74	29	at	at	ADV
fnp-5156	74	30	least	least	ADV
fnp-5156	74	31	50	50	NUM
fnp-5156	74	32	%	%	NOUN
fnp-5156	74	33	of	of	ADP
fnp-5156	74	34	the	the	DET
fnp-5156	74	35	short	short	ADJ
fnp-5156	74	36	or	or	CCONJ
fnp-5156	74	37	the	the	DET
fnp-5156	74	38	long	long	ADJ
fnp-5156	74	39	arm	arm	NOUN
fnp-5156	74	40	of	of	ADP
fnp-5156	74	41	chromosome	chromosome	NOUN
fnp-5156	74	42	10	10	NUM
fnp-5156	74	43	.	.	PUNCT
fnp-5156	75	1	the	the	DET
fnp-5156	75	2	7/10	7/10	NUM
fnp-5156	75	3	signature	signature	NOUN
fnp-5156	75	4	according	accord	VERB
fnp-5156	75	5	to	to	ADP
fnp-5156	75	6	this	this	DET
fnp-5156	75	7	guideline	guideline	NOUN
fnp-5156	75	8	was	be	AUX
fnp-5156	75	9	not	not	PART
fnp-5156	75	10	observed	observe	VERB
fnp-5156	75	11	at	at	ADV
fnp-5156	75	12	all	all	ADV
fnp-5156	75	13	in	in	ADP
fnp-5156	75	14	infant	infant	NOUN
fnp-5156	75	15	-	-	PUNCT
fnp-5156	75	16	type	type	NOUN
fnp-5156	75	17	hemispheric	hemispheric	ADJ
fnp-5156	75	18	glioma	glioma	NOUN
fnp-5156	75	19	.	.	PUNCT
fnp-5156	76	1	supratentorial	supratentorial	ADJ
fnp-5156	76	2	pilocytic	pilocytic	ADJ
fnp-5156	76	3	astrocytoma	astrocytoma	NOUN
fnp-5156	76	4	and	and	CCONJ
fnp-5156	76	5	ganglioglioma	ganglioglioma	PROPN
fnp-5156	76	6	typically	typically	ADV
fnp-5156	76	7	exhibiting	exhibit	VERB
fnp-5156	76	8	frequent	frequent	ADJ
fnp-5156	76	9	gain	gain	NOUN
fnp-5156	76	10	of	of	ADP
fnp-5156	76	11	chromosome	chromosome	NOUN
fnp-5156	76	12	7	7	NUM
fnp-5156	76	13	(	(	PUNCT
fnp-5156	76	14	figure	figure	NOUN
fnp-5156	76	15	3	3	NUM
fnp-5156	76	16	)	)	PUNCT
fnp-5156	76	17	both	both	PRON
fnp-5156	76	18	presented	present	VERB
fnp-5156	76	19	with	with	ADP
fnp-5156	76	20	the	the	DET
fnp-5156	76	21	7/10	7/10	NUM
fnp-5156	76	22	signature	signature	NOUN
fnp-5156	76	23	in	in	ADP
fnp-5156	76	24	1	1	NUM
fnp-5156	76	25	%	%	NOUN
fnp-5156	76	26	and	and	CCONJ
fnp-5156	76	27	2	2	NUM
fnp-5156	76	28	%	%	NOUN
fnp-5156	76	29	of	of	ADP
fnp-5156	76	30	the	the	DET
fnp-5156	76	31	cases	case	NOUN
fnp-5156	76	32	,	,	PUNCT
fnp-5156	76	33	respectively	respectively	ADV
fnp-5156	76	34	.	.	PUNCT
fnp-5156	77	1	likewise	likewise	ADV
fnp-5156	77	2	,	,	PUNCT
fnp-5156	77	3	the	the	DET
fnp-5156	77	4	7/10	7/10	NUM
fnp-5156	77	5	signature	signature	NOUN
fnp-5156	77	6	occurred	occur	VERB
fnp-5156	77	7	in	in	ADP
fnp-5156	77	8	only	only	ADV
fnp-5156	77	9	1	1	NUM
fnp-5156	77	10	%	%	NOUN
fnp-5156	77	11	of	of	ADP
fnp-5156	77	12	infratentorial	infratentorial	ADJ
fnp-5156	77	13	pilocytic	pilocytic	ADJ
fnp-5156	77	14	astrocytoma	astrocytoma	NOUN
fnp-5156	77	15	;	;	PUNCT
fnp-5156	77	16	however	however	ADV
fnp-5156	77	17	,	,	PUNCT
fnp-5156	77	18	this	this	DET
fnp-5156	77	19	tumor	tumor	NOUN
fnp-5156	77	20	group	group	NOUN
fnp-5156	77	21	much	much	ADV
fnp-5156	77	22	more	more	ADV
fnp-5156	77	23	rarely	rarely	ADV
fnp-5156	77	24	exhibited	exhibit	VERB
fnp-5156	77	25	chromosome	chromosome	NOUN
fnp-5156	77	26	7	7	NUM
fnp-5156	77	27	gains	gain	NOUN
fnp-5156	77	28	.	.	PUNCT
fnp-5156	78	1	only	only	ADV
fnp-5156	78	2	2	2	NUM
fnp-5156	78	3	%	%	NOUN
fnp-5156	78	4	of	of	ADP
fnp-5156	78	5	diffuse	diffuse	NOUN
fnp-5156	78	6	paediatric	paediatric	ADJ
fnp-5156	78	7	-	-	PUNCT
fnp-5156	78	8	type	type	NOUN
fnp-5156	78	9	high	high	ADJ
fnp-5156	78	10	grade	grade	NOUN
fnp-5156	78	11	glioma	glioma	NOUN
fnp-5156	78	12	,	,	PUNCT
fnp-5156	78	13	rtk1	rtk1	NOUN
fnp-5156	78	14	subtype	subtype	NOUN
fnp-5156	78	15	,	,	PUNCT
fnp-5156	78	16	subclass	subclass	VERB
fnp-5156	78	17	a	a	DET
fnp-5156	78	18	carried	carry	VERB
fnp-5156	78	19	the	the	DET
fnp-5156	78	20	7/10	7/10	NUM
fnp-5156	78	21	signature	signature	NOUN
fnp-5156	78	22	.	.	PUNCT
fnp-5156	79	1	among	among	ADP
fnp-5156	79	2	the	the	DET
fnp-5156	79	3	glioblastoma	glioblastoma	NOUN
fnp-5156	79	4	subtypes	subtype	NOUN
fnp-5156	79	5	we	we	PRON
fnp-5156	79	6	detected	detect	VERB
fnp-5156	79	7	a	a	DET
fnp-5156	79	8	presumably	presumably	ADV
fnp-5156	79	9	nonrandom	nonrandom	ADJ
fnp-5156	79	10	difference	difference	NOUN
fnp-5156	79	11	in	in	ADP
fnp-5156	79	12	the	the	DET
fnp-5156	79	13	frequency	frequency	NOUN
fnp-5156	79	14	of	of	ADP
fnp-5156	79	15	7/10	7/10	NUM
fnp-5156	79	16	signature	signature	NOUN
fnp-5156	79	17	ranging	range	VERB
fnp-5156	79	18	from	from	ADP
fnp-5156	79	19	38	38	NUM
fnp-5156	79	20	%	%	NOUN
fnp-5156	79	21	in	in	ADP
fnp-5156	79	22	mcgbmmes_atypical	mcgbmmes_atypical	ADJ
fnp-5156	79	23	to	to	PART
fnp-5156	79	24	92	92	NUM
fnp-5156	79	25	%	%	NOUN
fnp-5156	79	26	in	in	ADP
fnp-5156	79	27	gbm_rtk2	gbm_rtk2	PROPN
fnp-5156	79	28	.	.	PUNCT
fnp-5156	80	1	these	these	DET
fnp-5156	80	2	differences	difference	NOUN
fnp-5156	80	3	will	will	AUX
fnp-5156	80	4	be	be	AUX
fnp-5156	80	5	followed	follow	VERB
fnp-5156	80	6	up	up	ADP
fnp-5156	80	7	in	in	ADP
fnp-5156	80	8	a	a	DET
fnp-5156	80	9	larger	large	ADJ
fnp-5156	80	10	cohort	cohort	NOUN
fnp-5156	80	11	of	of	ADP
fnp-5156	80	12	glioblastomas	glioblastoma	NOUN
fnp-5156	80	13	.	.	PUNCT
fnp-5156	81	1	our	our	PRON
fnp-5156	81	2	study	study	NOUN
fnp-5156	81	3	demonstrated	demonstrate	VERB
fnp-5156	81	4	the	the	DET
fnp-5156	81	5	presence	presence	NOUN
fnp-5156	81	6	of	of	ADP
fnp-5156	81	7	the	the	DET
fnp-5156	81	8	7/10	7/10	NUM
fnp-5156	81	9	signature	signature	NOUN
fnp-5156	81	10	in	in	ADP
fnp-5156	81	11	24/165	24/165	NUM
fnp-5156	81	12	(	(	PUNCT
fnp-5156	81	13	15	15	NUM
fnp-5156	81	14	%	%	NOUN
fnp-5156	81	15	)	)	PUNCT
fnp-5156	81	16	mcpxaref	mcpxaref	NOUN
fnp-5156	81	17	and	and	CCONJ
fnp-5156	81	18	in	in	ADP
fnp-5156	81	19	145/767	145/767	NUM
fnp-5156	81	20	(	(	PUNCT
fnp-5156	81	21	19	19	NUM
fnp-5156	81	22	%	%	NOUN
fnp-5156	81	23	)	)	PUNCT
fnp-5156	81	24	mcpxa	mcpxa	NOUN
fnp-5156	81	25	.	.	PUNCT
fnp-5156	82	1	the	the	DET
fnp-5156	82	2	difference	difference	NOUN
fnp-5156	82	3	in	in	ADP
fnp-5156	82	4	frequencies	frequency	NOUN
fnp-5156	82	5	of	of	ADP
fnp-5156	82	6	the	the	DET
fnp-5156	82	7	7/10	7/10	NUM
fnp-5156	82	8	signature	signature	NOUN
fnp-5156	82	9	in	in	ADP
fnp-5156	82	10	both	both	DET
fnp-5156	82	11	groups	group	NOUN
fnp-5156	82	12	was	be	AUX
fnp-5156	82	13	not	not	PART
fnp-5156	82	14	significant	significant	ADJ
fnp-5156	82	15	(	(	PUNCT
fnp-5156	82	16	fisher	fisher	PROPN
fnp-5156	82	17	’s	’s	PART
fnp-5156	82	18	exact	exact	ADJ
fnp-5156	82	19	test	test	NOUN
fnp-5156	82	20	p	p	X
fnp-5156	82	21	>	>	X
fnp-5156	82	22	0.29	0.29	NUM
fnp-5156	82	23	)	)	PUNCT
fnp-5156	82	24	.	.	PUNCT
fnp-5156	83	1	the	the	DET
fnp-5156	83	2	distribution	distribution	NOUN
fnp-5156	83	3	of	of	ADP
fnp-5156	83	4	numerical	numerical	ADJ
fnp-5156	83	5	alterations	alteration	NOUN
fnp-5156	83	6	on	on	ADP
fnp-5156	83	7	the	the	DET
fnp-5156	83	8	chromosomal	chromosomal	ADJ
fnp-5156	83	9	arms	arm	NOUN
fnp-5156	83	10	7	7	NUM
fnp-5156	83	11	and	and	CCONJ
fnp-5156	83	12	10	10	NUM
fnp-5156	83	13	in	in	ADP
fnp-5156	83	14	mcpxaref	mcpxaref	NOUN
fnp-5156	83	15	,	,	PUNCT
fnp-5156	83	16	mcpxa	mcpxa	NOUN
fnp-5156	83	17	and	and	CCONJ
fnp-5156	83	18	the	the	DET
fnp-5156	83	19	11	11	NUM
fnp-5156	83	20	control	control	NOUN
fnp-5156	83	21	groups	group	NOUN
fnp-5156	83	22	is	be	AUX
fnp-5156	83	23	shown	show	VERB
fnp-5156	83	24	in	in	ADP
fnp-5156	83	25	table	table	NOUN
fnp-5156	83	26	1	1	NUM
fnp-5156	83	27	.	.	PUNCT
fnp-5156	83	28	data	datum	NOUN
fnp-5156	83	29	for	for	ADP
fnp-5156	83	30	2418	2418	NUM
fnp-5156	83	31	individual	individual	ADJ
fnp-5156	83	32	tumors	tumor	NOUN
fnp-5156	83	33	are	be	AUX
fnp-5156	83	34	provided	provide	VERB
fnp-5156	83	35	in	in	ADP
fnp-5156	83	36	supplementary	supplementary	ADJ
fnp-5156	83	37	table	table	NOUN
fnp-5156	83	38	3	3	NUM
fnp-5156	83	39	.	.	PUNCT
fnp-5156	83	40	group	group	NOUN
fnp-5156	83	41	n	n	PROPN
fnp-5156	83	42	7p	7p	PROPN
fnp-5156	83	43	7q	7q	PROPN
fnp-5156	83	44	10p	10p	NOUN
fnp-5156	83	45	10q	10q	NOUN
fnp-5156	83	46	7/10	7/10	NUM
fnp-5156	83	47	    	    	SPACE
fnp-5156	83	48	(	(	PUNCT
fnp-5156	83	49	gain>50	gain>50	PROPN
fnp-5156	83	50	%	%	NOUN
fnp-5156	83	51	)	)	PUNCT
fnp-5156	83	52	(	(	PUNCT
fnp-5156	83	53	gain>50	gain>50	NOUN
fnp-5156	83	54	%	%	NOUN
fnp-5156	83	55	)	)	PUNCT
fnp-5156	83	56	(	(	PUNCT
fnp-5156	83	57	gain>50	gain>50	NOUN
fnp-5156	83	58	%	%	NOUN
fnp-5156	83	59	)	)	PUNCT
fnp-5156	83	60	(	(	PUNCT
fnp-5156	83	61	gain>50	gain>50	NOUN
fnp-5156	83	62	%	%	NOUN
fnp-5156	83	63	)	)	PUNCT
fnp-5156	83	64	(	(	PUNCT
fnp-5156	83	65	signature	signature	NOUN
fnp-5156	83	66	)	)	PUNCT
fnp-5156	84	1	mcpedhgg_rtk1a	mcpedhgg_rtk1a	PROPN
fnp-5156	84	2	100	100	NUM
fnp-5156	84	3	10	10	NUM
fnp-5156	84	4	4	4	NUM
fnp-5156	84	5	11	11	NUM
fnp-5156	84	6	6	6	NUM
fnp-5156	84	7	2	2	NUM
fnp-5156	84	8	mcgg	mcgg	NOUN
fnp-5156	84	9	100	100	NUM
fnp-5156	84	10	29	29	NUM
fnp-5156	84	11	30	30	NUM
fnp-5156	84	12	3	3	NUM
fnp-5156	84	13	3	3	NUM
fnp-5156	84	14	2	2	NUM
fnp-5156	84	15	mcgbm_mes_atyp	mcgbm_mes_atyp	NOUN
fnp-5156	84	16	100	100	NUM
fnp-5156	84	17	60	60	NUM
fnp-5156	84	18	54	54	NUM
fnp-5156	84	19	57	57	NUM
fnp-5156	84	20	51	51	NUM
fnp-5156	84	21	38	38	NUM
fnp-5156	84	22	mcgbm_rtk1	mcgbm_rtk1	NOUN
fnp-5156	84	23	100	100	NUM
fnp-5156	84	24	82	82	NUM
fnp-5156	84	25	80	80	NUM
fnp-5156	84	26	82	82	NUM
fnp-5156	84	27	86	86	NUM
fnp-5156	84	28	75	75	NUM
fnp-5156	84	29	mcgbm_rtk2	mcgbm_rtk2	NOUN
fnp-5156	84	30	100	100	NUM
fnp-5156	84	31	84	84	NUM
fnp-5156	84	32	88	88	NUM
fnp-5156	84	33	98	98	NUM
fnp-5156	84	34	95	95	NUM
fnp-5156	84	35	92	92	NUM
fnp-5156	84	36	mcgbm_mes_typ	mcgbm_mes_typ	NOUN
fnp-5156	84	37	100	100	NUM
fnp-5156	84	38	76	76	NUM
fnp-5156	84	39	76	76	NUM
fnp-5156	84	40	77	77	NUM
fnp-5156	84	41	78	78	NUM
fnp-5156	84	42	64	64	NUM
fnp-5156	84	43	mchgap	mchgap	NOUN
fnp-5156	84	44	100	100	NUM
fnp-5156	84	45	5	5	NUM
fnp-5156	84	46	6	6	NUM
fnp-5156	84	47	28	28	NUM
fnp-5156	84	48	7	7	NUM
fnp-5156	84	49	5	5	NUM
fnp-5156	84	50	mcihg	mcihg	VERB
fnp-5156	84	51	100	100	NUM
fnp-5156	84	52	4	4	NUM
fnp-5156	84	53	4	4	NUM
fnp-5156	84	54	8	8	NUM
fnp-5156	84	55	5	5	NUM
fnp-5156	84	56	0	0	NUM
fnp-5156	84	57	mcpa_inf	mcpa_inf	NUM
fnp-5156	84	58	100	100	NUM
fnp-5156	84	59	10	10	NUM
fnp-5156	84	60	11	11	NUM
fnp-5156	84	61	0	0	NUM
fnp-5156	84	62	1	1	NUM
fnp-5156	84	63	1	1	NUM
fnp-5156	84	64	mcnet_patz1	mcnet_patz1	NOUN
fnp-5156	84	65	100	100	NUM
fnp-5156	84	66	5	5	NUM
fnp-5156	84	67	6	6	NUM
fnp-5156	84	68	8	8	NUM
fnp-5156	84	69	10	10	NUM
fnp-5156	84	70	1	1	NUM
fnp-5156	84	71	mcpa_cort	mcpa_cort	NOUN
fnp-5156	84	72	100	100	NUM
fnp-5156	84	73	28	28	NUM
fnp-5156	84	74	26	26	NUM
fnp-5156	84	75	1	1	NUM
fnp-5156	84	76	0	0	NUM
fnp-5156	84	77	1	1	NUM
fnp-5156	84	78	mcpxa	mcpxa	NOUN
fnp-5156	84	79	767	767	NUM
fnp-5156	84	80	268	268	NUM
fnp-5156	84	81	244	244	NUM
fnp-5156	84	82	291	291	NUM
fnp-5156	84	83	257	257	NUM
fnp-5156	84	84	145	145	NUM
fnp-5156	84	85	(	(	PUNCT
fnp-5156	84	86	19	19	NUM
fnp-5156	84	87	%	%	NOUN
fnp-5156	84	88	)	)	PUNCT
fnp-5156	84	89	mcpxaref	mcpxaref	NOUN
fnp-5156	84	90	165	165	NUM
fnp-5156	84	91	50	50	NUM
fnp-5156	84	92	48	48	NUM
fnp-5156	84	93	49	49	NUM
fnp-5156	84	94	44	44	NUM
fnp-5156	84	95	24	24	NUM
fnp-5156	84	96	(	(	PUNCT
fnp-5156	84	97	15	15	NUM
fnp-5156	84	98	%	%	NOUN
fnp-5156	84	99	)	)	PUNCT
fnp-5156	84	100	sum	sum	NOUN
fnp-5156	84	101	2032	2032	NUM
fnp-5156	84	102	          	          	SPACE
fnp-5156	84	103	table	table	NOUN
fnp-5156	84	104	1	1	NUM
fnp-5156	84	105	:	:	PUNCT
fnp-5156	84	106	distribution	distribution	NOUN
fnp-5156	84	107	of	of	ADP
fnp-5156	84	108	chromosomal	chromosomal	ADJ
fnp-5156	84	109	7	7	NUM
fnp-5156	84	110	gains	gain	NOUN
fnp-5156	84	111	and	and	CCONJ
fnp-5156	84	112	10	10	NUM
fnp-5156	84	113	losses	loss	NOUN
fnp-5156	84	114	in	in	ADP
fnp-5156	84	115	mcpxa	mcpxa	NOUN
fnp-5156	84	116	,	,	PUNCT
fnp-5156	84	117	mcpxaref	mcpxaref	ADJ
fnp-5156	84	118	and	and	CCONJ
fnp-5156	84	119	in	in	ADP
fnp-5156	84	120	reference	reference	NOUN
fnp-5156	84	121	sets	set	VERB
fnp-5156	84	122	prevalence	prevalence	NOUN
fnp-5156	84	123	of	of	ADP
fnp-5156	84	124	the	the	DET
fnp-5156	84	125	cdkn2a	cdkn2a	PROPN
fnp-5156	84	126	/	/	SYM
fnp-5156	84	127	b	b	NOUN
fnp-5156	84	128	homozygous	homozygous	ADJ
fnp-5156	84	129	deletion	deletion	NOUN
fnp-5156	84	130	and	and	CCONJ
fnp-5156	84	131	gene	gene	NOUN
fnp-5156	84	132	amplifications	amplification	NOUN
fnp-5156	84	133	in	in	ADP
fnp-5156	84	134	mcpxa	mcpxa	NOUN
fnp-5156	84	135	,	,	PUNCT
fnp-5156	84	136	mcpxaref	mcpxaref	ADJ
fnp-5156	84	137	and	and	CCONJ
fnp-5156	84	138	reference	reference	NOUN
fnp-5156	84	139	sets	set	VERB
fnp-5156	84	140	a	a	DET
fnp-5156	84	141	hallmark	hallmark	ADJ
fnp-5156	84	142	chromosomal	chromosomal	ADJ
fnp-5156	84	143	numerical	numerical	ADJ
fnp-5156	84	144	alteration	alteration	NOUN
fnp-5156	84	145	in	in	ADP
fnp-5156	84	146	pxa	pxa	NOUN
fnp-5156	84	147	is	be	AUX
fnp-5156	84	148	a	a	DET
fnp-5156	84	149	homozygous	homozygous	ADJ
fnp-5156	84	150	deletion	deletion	NOUN
fnp-5156	84	151	on	on	ADP
fnp-5156	84	152	chromosomal	chromosomal	ADJ
fnp-5156	84	153	arm	arm	NOUN
fnp-5156	84	154	9p	9p	NOUN
fnp-5156	84	155	including	include	VERB
fnp-5156	84	156	the	the	DET
fnp-5156	84	157	cdkn2a	cdkn2a	PROPN
fnp-5156	84	158	/	/	SYM
fnp-5156	84	159	b	b	NOUN
fnp-5156	84	160	locus	locus	NOUN
fnp-5156	84	161	(	(	PUNCT
fnp-5156	84	162	7,10	7,10	NUM
fnp-5156	84	163	)	)	PUNCT
fnp-5156	84	164	.	.	PUNCT
fnp-5156	85	1	this	this	DET
fnp-5156	85	2	alteration	alteration	NOUN
fnp-5156	85	3	was	be	AUX
fnp-5156	85	4	seen	see	VERB
fnp-5156	85	5	in	in	ADP
fnp-5156	85	6	147/165	147/165	PROPN
fnp-5156	85	7	(	(	PUNCT
fnp-5156	85	8	89	89	NUM
fnp-5156	85	9	%	%	NOUN
fnp-5156	85	10	)	)	PUNCT
fnp-5156	85	11	mcpxaref	mcpxaref	NOUN
fnp-5156	85	12	and	and	CCONJ
fnp-5156	85	13	in	in	ADP
fnp-5156	85	14	685/767	685/767	PROPN
fnp-5156	85	15	(	(	PUNCT
fnp-5156	85	16	89	89	NUM
fnp-5156	85	17	%	%	NOUN
fnp-5156	85	18	)	)	PUNCT
fnp-5156	85	19	mcpxa	mcpxa	NOUN
fnp-5156	85	20	.	.	PUNCT
fnp-5156	86	1	due	due	ADP
fnp-5156	86	2	to	to	ADP
fnp-5156	86	3	the	the	DET
fnp-5156	86	4	high	high	ADJ
fnp-5156	86	5	frequency	frequency	NOUN
fnp-5156	86	6	of	of	ADP
fnp-5156	86	7	this	this	DET
fnp-5156	86	8	alteration	alteration	NOUN
fnp-5156	86	9	in	in	ADP
fnp-5156	86	10	gbm	gbm	NOUN
fnp-5156	86	11	,	,	PUNCT
fnp-5156	86	12	pxa	pxa	NOUN
fnp-5156	86	13	can	can	AUX
fnp-5156	86	14	not	not	PART
fnp-5156	86	15	be	be	AUX
fnp-5156	86	16	separated	separate	VERB
fnp-5156	86	17	from	from	ADP
fnp-5156	86	18	gbm	gbm	PROPN
fnp-5156	86	19	on	on	ADP
fnp-5156	86	20	these	these	DET
fnp-5156	86	21	grounds	ground	NOUN
fnp-5156	86	22	.	.	PUNCT
fnp-5156	87	1	again	again	ADV
fnp-5156	87	2	,	,	PUNCT
fnp-5156	87	3	we	we	PRON
fnp-5156	87	4	observed	observe	VERB
fnp-5156	87	5	different	different	ADJ
fnp-5156	87	6	frequencies	frequency	NOUN
fnp-5156	87	7	of	of	ADP
fnp-5156	87	8	homozygous	homozygous	ADJ
fnp-5156	87	9	cdkn2a	cdkn2a	PROPN
fnp-5156	87	10	/	/	SYM
fnp-5156	87	11	b	b	NOUN
fnp-5156	87	12	deletions	deletion	NOUN
fnp-5156	87	13	in	in	ADP
fnp-5156	87	14	gbm	gbm	PROPN
fnp-5156	87	15	subgroups	subgroup	NOUN
fnp-5156	87	16	,	,	PUNCT
fnp-5156	87	17	ranging	range	VERB
fnp-5156	87	18	from	from	ADP
fnp-5156	87	19	40	40	NUM
fnp-5156	87	20	%	%	NOUN
fnp-5156	87	21	in	in	ADP
fnp-5156	87	22	glioblastoma	glioblastoma	NOUN
fnp-5156	87	23	,	,	PUNCT
fnp-5156	87	24	idh	idh	NOUN
fnp-5156	87	25	-	-	PUNCT
fnp-5156	87	26	wildtype	wildtype	NOUN
fnp-5156	87	27	,	,	PUNCT
fnp-5156	87	28	mesenchymal	mesenchymal	NOUN
fnp-5156	87	29	to	to	ADP
fnp-5156	87	30	79	79	NUM
fnp-5156	87	31	%	%	NOUN
fnp-5156	87	32	in	in	ADP
fnp-5156	87	33	glioblastoma	glioblastoma	NOUN
fnp-5156	87	34	,	,	PUNCT
fnp-5156	87	35	idh	idh	NOUN
fnp-5156	87	36	-	-	PUNCT
fnp-5156	87	37	wildtype	wildtype	NOUN
fnp-5156	87	38	,	,	PUNCT
fnp-5156	87	39	rtk2	rtk2	NOUN
fnp-5156	87	40	.	.	PUNCT
fnp-5156	88	1	the	the	DET
fnp-5156	88	2	differences	difference	NOUN
fnp-5156	88	3	likely	likely	ADV
fnp-5156	88	4	are	be	AUX
fnp-5156	88	5	non	non	ADJ
fnp-5156	88	6	-	-	ADJ
fnp-5156	88	7	random	random	ADJ
fnp-5156	88	8	and	and	CCONJ
fnp-5156	88	9	will	will	AUX
fnp-5156	88	10	be	be	AUX
fnp-5156	88	11	followed	follow	VERB
fnp-5156	88	12	up	up	ADP
fnp-5156	88	13	.	.	PUNCT
fnp-5156	89	1	as	as	SCONJ
fnp-5156	89	2	expected	expect	VERB
fnp-5156	89	3	,	,	PUNCT
fnp-5156	89	4	high	high	ADJ
fnp-5156	89	5	-	-	PUNCT
fnp-5156	89	6	grade	grade	NOUN
fnp-5156	89	7	astrocytoma	astrocytoma	NOUN
fnp-5156	89	8	with	with	ADP
fnp-5156	89	9	piloid	piloid	PROPN
fnp-5156	89	10	features	feature	NOUN
fnp-5156	89	11	exhibited	exhibit	VERB
fnp-5156	89	12	a	a	DET
fnp-5156	89	13	high	high	ADJ
fnp-5156	89	14	proportion	proportion	NOUN
fnp-5156	89	15	of	of	ADP
fnp-5156	89	16	homozygous	homozygous	ADJ
fnp-5156	89	17	cdkn2a	cdkn2a	PROPN
fnp-5156	89	18	/	/	SYM
fnp-5156	89	19	b	b	NOUN
fnp-5156	89	20	deletions	deletion	NOUN
fnp-5156	89	21	(	(	PUNCT
fnp-5156	89	22	80	80	NUM
fnp-5156	89	23	%	%	NOUN
fnp-5156	89	24	)	)	PUNCT
fnp-5156	89	25	.	.	PUNCT
fnp-5156	90	1	gene	gene	NOUN
fnp-5156	90	2	amplifications	amplification	NOUN
fnp-5156	90	3	affecting	affect	VERB
fnp-5156	90	4	egfr	egfr	NOUN
fnp-5156	90	5	,	,	PUNCT
fnp-5156	90	6	mdm2	mdm2	PROPN
fnp-5156	90	7	and	and	CCONJ
fnp-5156	90	8	pdgfra	pdgfra	NOUN
fnp-5156	90	9	were	be	AUX
fnp-5156	90	10	rare	rare	ADJ
fnp-5156	90	11	in	in	ADP
fnp-5156	90	12	mcpxa	mcpxa	NOUN
fnp-5156	90	13	and	and	CCONJ
fnp-5156	90	14	pxa	pxa	NOUN
fnp-5156	90	15	.	.	PUNCT
fnp-5156	91	1	highest	high	ADJ
fnp-5156	91	2	incidences	incidence	NOUN
fnp-5156	91	3	for	for	ADP
fnp-5156	91	4	egfr	egfr	ADJ
fnp-5156	91	5	amplification	amplification	NOUN
fnp-5156	91	6	were	be	AUX
fnp-5156	91	7	observed	observe	VERB
fnp-5156	91	8	in	in	ADP
fnp-5156	91	9	glioblastoma	glioblastoma	NOUN
fnp-5156	91	10	,	,	PUNCT
fnp-5156	91	11	idh	idh	NOUN
fnp-5156	91	12	-	-	PUNCT
fnp-5156	91	13	wildtype	wildtype	NOUN
fnp-5156	91	14	,	,	PUNCT
fnp-5156	91	15	rtk2	rtk2	NOUN
fnp-5156	91	16	(	(	PUNCT
fnp-5156	91	17	86	86	NUM
fnp-5156	91	18	%	%	NOUN
fnp-5156	91	19	)	)	PUNCT
fnp-5156	91	20	,	,	PUNCT
fnp-5156	91	21	for	for	ADP
fnp-5156	91	22	mdm2	mdm2	NOUN
fnp-5156	91	23	amplification	amplification	NOUN
fnp-5156	91	24	in	in	ADP
fnp-5156	91	25	glioblastoma	glioblastoma	NOUN
fnp-5156	91	26	,	,	PUNCT
fnp-5156	91	27	idh	idh	NOUN
fnp-5156	91	28	-	-	PUNCT
fnp-5156	91	29	wildtype	wildtype	NOUN
fnp-5156	91	30	,	,	PUNCT
fnp-5156	91	31	rtk1	rtk1	PROPN
fnp-5156	91	32	(	(	PUNCT
fnp-5156	91	33	23	23	NUM
fnp-5156	91	34	%	%	NOUN
fnp-5156	91	35	)	)	PUNCT
fnp-5156	91	36	and	and	CCONJ
fnp-5156	91	37	for	for	ADP
fnp-5156	91	38	pdgfra	pdgfra	ADJ
fnp-5156	91	39	amplification	amplification	NOUN
fnp-5156	91	40	also	also	ADV
fnp-5156	91	41	in	in	ADP
fnp-5156	91	42	glioblastoma	glioblastoma	NOUN
fnp-5156	91	43	,	,	PUNCT
fnp-5156	91	44	idh	idh	NOUN
fnp-5156	91	45	-	-	PUNCT
fnp-5156	91	46	wildtype	wildtype	NOUN
fnp-5156	91	47	,	,	PUNCT
fnp-5156	91	48	rtk1	rtk1	PROPN
fnp-5156	91	49	(	(	PUNCT
fnp-5156	91	50	18	18	NUM
fnp-5156	91	51	%	%	NOUN
fnp-5156	91	52	)	)	PUNCT
fnp-5156	91	53	.	.	PUNCT
fnp-5156	92	1	the	the	DET
fnp-5156	92	2	distribution	distribution	NOUN
fnp-5156	92	3	of	of	ADP
fnp-5156	92	4	homozygous	homozygous	ADJ
fnp-5156	92	5	cdkn2a	cdkn2a	PROPN
fnp-5156	92	6	/	/	SYM
fnp-5156	92	7	b	b	NOUN
fnp-5156	92	8	deletions	deletion	NOUN
fnp-5156	92	9	in	in	ADP
fnp-5156	92	10	mcpxaref	mcpxaref	NOUN
fnp-5156	92	11	,	,	PUNCT
fnp-5156	92	12	mcpxa	mcpxa	NOUN
fnp-5156	92	13	and	and	CCONJ
fnp-5156	92	14	reference	reference	NOUN
fnp-5156	92	15	sets	set	VERB
fnp-5156	92	16	as	as	ADV
fnp-5156	92	17	well	well	ADV
fnp-5156	92	18	as	as	ADP
fnp-5156	92	19	the	the	DET
fnp-5156	92	20	distribution	distribution	NOUN
fnp-5156	92	21	for	for	ADP
fnp-5156	92	22	gene	gene	NOUN
fnp-5156	92	23	amplifications	amplification	NOUN
fnp-5156	92	24	is	be	AUX
fnp-5156	92	25	given	give	VERB
fnp-5156	92	26	in	in	ADP
fnp-5156	92	27	table	table	NOUN
fnp-5156	92	28	2	2	NUM
fnp-5156	92	29	.	.	PUNCT
fnp-5156	92	30	data	datum	NOUN
fnp-5156	92	31	for	for	ADP
fnp-5156	92	32	2418	2418	NUM
fnp-5156	92	33	individual	individual	ADJ
fnp-5156	92	34	tumors	tumor	NOUN
fnp-5156	92	35	are	be	AUX
fnp-5156	92	36	provided	provide	VERB
fnp-5156	92	37	in	in	ADP
fnp-5156	92	38	supplementary	supplementary	ADJ
fnp-5156	92	39	table	table	NOUN
fnp-5156	92	40	4	4	NUM
fnp-5156	92	41	.	.	PUNCT
fnp-5156	92	42	group	group	NOUN
fnp-5156	92	43	n	n	PROPN
fnp-5156	92	44	egfr	egfr	NOUN
fnp-5156	92	45	amp	amp	PROPN
fnp-5156	92	46	mdm2	mdm2	PROPN
fnp-5156	92	47	amp	amp	PROPN
fnp-5156	92	48	pdgfra	pdgfra	PROPN
fnp-5156	92	49	amp	amp	PROPN
fnp-5156	92	50	cdkn2a	cdkn2a	PROPN
fnp-5156	92	51	/	/	SYM
fnp-5156	92	52	b	b	NOUN
fnp-5156	92	53	    	    	SPACE
fnp-5156	92	54	(	(	PUNCT
fnp-5156	92	55	gain>5.5	gain>5.5	PROPN
fnp-5156	92	56	)	)	PUNCT
fnp-5156	92	57	(	(	PUNCT
fnp-5156	92	58	gain>5.5	gain>5.5	PROPN
fnp-5156	92	59	)	)	PUNCT
fnp-5156	92	60	(	(	PUNCT
fnp-5156	92	61	gain>5.5	gain>5.5	PROPN
fnp-5156	92	62	)	)	PUNCT
fnp-5156	92	63	(	(	PUNCT
fnp-5156	92	64	loss	loss	NOUN
fnp-5156	92	65	mcpedhgg_rtk1a	mcpedhgg_rtk1a	PROPN
fnp-5156	92	66	100	100	NUM
fnp-5156	92	67	2	2	NUM
fnp-5156	92	68	3	3	NUM
fnp-5156	92	69	13	13	NUM
fnp-5156	92	70	23	23	NUM
fnp-5156	92	71	mcgg	mcgg	NOUN
fnp-5156	92	72	100	100	NUM
fnp-5156	92	73	0	0	NUM
fnp-5156	92	74	0	0	NUM
fnp-5156	92	75	0	0	NUM
fnp-5156	92	76	0	0	NUM
fnp-5156	92	77	mcgbm_mes_atyp	mcgbm_mes_atyp	NOUN
fnp-5156	92	78	100	100	NUM
fnp-5156	92	79	2	2	NUM
fnp-5156	92	80	0	0	NUM
fnp-5156	92	81	1	1	NUM
fnp-5156	92	82	45	45	NUM
fnp-5156	92	83	mcgbm_rtk1	mcgbm_rtk1	NOUN
fnp-5156	92	84	100	100	NUM
fnp-5156	92	85	14	14	NUM
fnp-5156	92	86	23	23	NUM
fnp-5156	92	87	18	18	NUM
fnp-5156	92	88	52	52	NUM
fnp-5156	92	89	mcgbm_rtk2	mcgbm_rtk2	NOUN
fnp-5156	92	90	100	100	NUM
fnp-5156	92	91	86	86	NUM
fnp-5156	92	92	11	11	NUM
fnp-5156	92	93	5	5	NUM
fnp-5156	92	94	79	79	NUM
fnp-5156	92	95	mcgbm_mes_typ	mcgbm_mes_typ	NOUN
fnp-5156	92	96	100	100	NUM
fnp-5156	92	97	21	21	NUM
fnp-5156	92	98	4	4	NUM
fnp-5156	92	99	0	0	NUM
fnp-5156	92	100	40	40	NUM
fnp-5156	92	101	mchgap	mchgap	NOUN
fnp-5156	92	102	100	100	NUM
fnp-5156	92	103	0	0	NUM
fnp-5156	92	104	2	2	NUM
fnp-5156	92	105	0	0	NUM
fnp-5156	92	106	80	80	NUM
fnp-5156	92	107	mcihg	mcihg	VERB
fnp-5156	92	108	100	100	NUM
fnp-5156	92	109	0	0	NUM
fnp-5156	92	110	0	0	NUM
fnp-5156	92	111	0	0	NUM
fnp-5156	92	112	2	2	NUM
fnp-5156	92	113	mcpa_inf	mcpa_inf	NUM
fnp-5156	92	114	100	100	NUM
fnp-5156	92	115	0	0	NUM
fnp-5156	92	116	1	1	NUM
fnp-5156	92	117	1	1	NUM
fnp-5156	92	118	0	0	NUM
fnp-5156	92	119	mcnet_patz1	mcnet_patz1	NOUN
fnp-5156	92	120	100	100	NUM
fnp-5156	92	121	0	0	NUM
fnp-5156	92	122	0	0	NUM
fnp-5156	92	123	0	0	NUM
fnp-5156	92	124	3	3	NUM
fnp-5156	92	125	mcpa_cort	mcpa_cort	NOUN
fnp-5156	92	126	100	100	NUM
fnp-5156	92	127	0	0	NUM
fnp-5156	92	128	0	0	NUM
fnp-5156	92	129	0	0	NUM
fnp-5156	92	130	0	0	NUM
fnp-5156	93	1	mcpxa	mcpxa	NOUN
fnp-5156	93	2	767	767	NUM
fnp-5156	93	3	2	2	NUM
fnp-5156	93	4	4	4	NUM
fnp-5156	93	5	1	1	NUM
fnp-5156	93	6	685	685	NUM
fnp-5156	93	7	(	(	PUNCT
fnp-5156	93	8	89	89	NUM
fnp-5156	93	9	%	%	NOUN
fnp-5156	93	10	)	)	PUNCT
fnp-5156	93	11	mcpxaref	mcpxaref	NOUN
fnp-5156	93	12	165	165	NUM
fnp-5156	93	13	0	0	NUM
fnp-5156	93	14	2	2	NUM
fnp-5156	93	15	0	0	NUM
fnp-5156	93	16	147	147	NUM
fnp-5156	93	17	(	(	PUNCT
fnp-5156	93	18	89	89	NUM
fnp-5156	93	19	%	%	NOUN
fnp-5156	93	20	)	)	PUNCT
fnp-5156	93	21	sum	sum	NOUN
fnp-5156	93	22	2032	2032	NUM
fnp-5156	93	23	        	        	SPACE
fnp-5156	93	24	table	table	NOUN
fnp-5156	93	25	2	2	NUM
fnp-5156	93	26	:	:	PUNCT
fnp-5156	93	27	distribution	distribution	NOUN
fnp-5156	93	28	of	of	ADP
fnp-5156	93	29	amplifications	amplification	NOUN
fnp-5156	93	30	and	and	CCONJ
fnp-5156	93	31	homozygous	homozygous	ADJ
fnp-5156	93	32	cdkn2a	cdkn2a	PROPN
fnp-5156	93	33	/	/	SYM
fnp-5156	93	34	b	b	NOUN
fnp-5156	93	35	deletions	deletion	NOUN
fnp-5156	93	36	in	in	ADP
fnp-5156	93	37	mcpxa	mcpxa	NOUN
fnp-5156	93	38	,	,	PUNCT
fnp-5156	93	39	mcpxaref	mcpxaref	ADJ
fnp-5156	93	40	and	and	CCONJ
fnp-5156	93	41	in	in	ADP
fnp-5156	93	42	reference	reference	NOUN
fnp-5156	93	43	sets	set	VERB
fnp-5156	93	44	predictions	prediction	NOUN
fnp-5156	93	45	in	in	ADP
fnp-5156	93	46	tumors	tumor	NOUN
fnp-5156	93	47	diagnosed	diagnose	VERB
fnp-5156	93	48	as	as	ADP
fnp-5156	93	49	pxa	pxa	NOUN
fnp-5156	93	50	in	in	ADP
fnp-5156	93	51	the	the	DET
fnp-5156	93	52	551	551	NUM
fnp-5156	93	53	tumors	tumor	NOUN
fnp-5156	93	54	which	which	PRON
fnp-5156	93	55	received	receive	VERB
fnp-5156	93	56	the	the	DET
fnp-5156	93	57	diagnosis	diagnosis	NOUN
fnp-5156	93	58	or	or	CCONJ
fnp-5156	93	59	differential	differential	ADJ
fnp-5156	93	60	diagnosis	diagnosis	NOUN
fnp-5156	93	61	pxa	pxa	NOUN
fnp-5156	93	62	,	,	PUNCT
fnp-5156	93	63	296	296	NUM
fnp-5156	93	64	tumors	tumor	NOUN
fnp-5156	93	65	received	receive	VERB
fnp-5156	93	66	a	a	DET
fnp-5156	93	67	score	score	NOUN
fnp-5156	93	68	>	>	PUNCT
fnp-5156	93	69	=	=	X
fnp-5156	93	70	0.9	0.9	NUM
fnp-5156	93	71	.	.	PUNCT
fnp-5156	94	1	highest	high	ADJ
fnp-5156	94	2	numbers	number	NOUN
fnp-5156	94	3	for	for	ADP
fnp-5156	94	4	predictions	prediction	NOUN
fnp-5156	94	5	(	(	PUNCT
fnp-5156	94	6	all	all	DET
fnp-5156	94	7	scores	score	NOUN
fnp-5156	94	8	/	/	SYM
fnp-5156	94	9	scores	score	NOUN
fnp-5156	94	10	>	>	X
fnp-5156	94	11	=	=	SYM
fnp-5156	94	12	0,9	0,9	NUM
fnp-5156	94	13	)	)	PUNCT
fnp-5156	94	14	were	be	AUX
fnp-5156	94	15	received	receive	VERB
fnp-5156	94	16	for	for	ADP
fnp-5156	94	17	mcpxa	mcpxa	NOUN
fnp-5156	94	18	(	(	PUNCT
fnp-5156	94	19	208/165	208/165	NUM
fnp-5156	94	20	)	)	PUNCT
fnp-5156	94	21	,	,	PUNCT
fnp-5156	94	22	mcgbm_mes_typ	mcgbm_mes_typ	X
fnp-5156	94	23	(	(	PUNCT
fnp-5156	94	24	108/59	108/59	NUM
fnp-5156	94	25	)	)	PUNCT
fnp-5156	94	26	,	,	PUNCT
fnp-5156	94	27	mcpa_cort	mcpa_cort	PROPN
fnp-5156	94	28	(	(	PUNCT
fnp-5156	94	29	22/11	22/11	NUM
fnp-5156	94	30	)	)	PUNCT
fnp-5156	94	31	,	,	PUNCT
fnp-5156	94	32	methylation	methylation	NOUN
fnp-5156	94	33	class	class	NOUN
fnp-5156	94	34	control	control	NOUN
fnp-5156	94	35	tissue	tissue	NOUN
fnp-5156	94	36	,	,	PUNCT
fnp-5156	94	37	reactive	reactive	ADJ
fnp-5156	94	38	tumor	tumor	NOUN
fnp-5156	94	39	microenvironment	microenvironment	NOUN
fnp-5156	94	40	(	(	PUNCT
fnp-5156	94	41	mcctrlmicro	mcctrlmicro	PROPN
fnp-5156	94	42	)	)	PUNCT
fnp-5156	94	43	(	(	PUNCT
fnp-5156	94	44	30/8	30/8	NUM
fnp-5156	94	45	)	)	PUNCT
fnp-5156	94	46	,	,	PUNCT
fnp-5156	94	47	mcgbm_rtk2	mcgbm_rtk2	NOUN
fnp-5156	94	48	(	(	PUNCT
fnp-5156	94	49	13/6	13/6	NUM
fnp-5156	94	50	)	)	PUNCT
fnp-5156	94	51	,	,	PUNCT
fnp-5156	94	52	mchgap	mchgap	NOUN
fnp-5156	94	53	(	(	PUNCT
fnp-5156	94	54	15/5	15/5	NUM
fnp-5156	94	55	)	)	PUNCT
fnp-5156	94	56	,	,	PUNCT
fnp-5156	94	57	mcihg	mcihg	VERB
fnp-5156	94	58	(	(	PUNCT
fnp-5156	94	59	5/4	5/4	NUM
fnp-5156	94	60	)	)	PUNCT
fnp-5156	94	61	,	,	PUNCT
fnp-5156	94	62	mcgbm_rtk1	mcgbm_rtk1	PROPN
fnp-5156	94	63	(	(	PUNCT
fnp-5156	94	64	4/3	4/3	NUM
fnp-5156	94	65	)	)	PUNCT
fnp-5156	94	66	,	,	PUNCT
fnp-5156	94	67	mcpa_inf	mcpa_inf	PROPN
fnp-5156	94	68	(	(	PUNCT
fnp-5156	94	69	3/3	3/3	NUM
fnp-5156	94	70	)	)	PUNCT
fnp-5156	94	71	,	,	PUNCT
fnp-5156	94	72	mcnet_patz1	mcnet_patz1	X
fnp-5156	94	73	(	(	PUNCT
fnp-5156	94	74	4/3	4/3	NUM
fnp-5156	94	75	)	)	PUNCT
fnp-5156	94	76	,	,	PUNCT
fnp-5156	94	77	methylation	methylation	NOUN
fnp-5156	94	78	class	class	NOUN
fnp-5156	94	79	astrocytoma	astrocytoma	NOUN
fnp-5156	94	80	,	,	PUNCT
fnp-5156	94	81	idh	idh	NOUN
fnp-5156	94	82	-	-	PUNCT
fnp-5156	94	83	mutant	mutant	NOUN
fnp-5156	94	84	(	(	PUNCT
fnp-5156	94	85	mcaidhmut	mcaidhmut	NOUN
fnp-5156	94	86	)	)	PUNCT
fnp-5156	94	87	(	(	PUNCT
fnp-5156	94	88	3/2	3/2	NUM
fnp-5156	94	89	)	)	PUNCT
fnp-5156	94	90	,	,	PUNCT
fnp-5156	94	91	mc	mc	PROPN
fnp-5156	94	92	diffuse	diffuse	VERB
fnp-5156	94	93	hemispheric	hemispheric	ADJ
fnp-5156	94	94	glioma	glioma	NOUN
fnp-5156	94	95	,	,	PUNCT
fnp-5156	94	96	h3	h3	VERB
fnp-5156	94	97	g34	g34	NOUN
fnp-5156	94	98	-	-	PUNCT
fnp-5156	94	99	mutant	mutant	NOUN
fnp-5156	94	100	(	(	PUNCT
fnp-5156	94	101	dhgh3mut	dhgh3mut	NOUN
fnp-5156	94	102	)	)	PUNCT
fnp-5156	94	103	(	(	PUNCT
fnp-5156	94	104	2/2	2/2	NUM
fnp-5156	94	105	)	)	PUNCT
fnp-5156	94	106	,	,	PUNCT
fnp-5156	95	1	mcpedhgg_rtk1a	mcpedhgg_rtk1a	PROPN
fnp-5156	95	2	(	(	PUNCT
fnp-5156	95	3	5/2	5/2	NUM
fnp-5156	95	4	)	)	PUNCT
fnp-5156	95	5	,	,	PUNCT
fnp-5156	95	6	mcgg	mcgg	NOUN
fnp-5156	95	7	(	(	PUNCT
fnp-5156	95	8	12/2	12/2	NUM
fnp-5156	95	9	)	)	PUNCT
fnp-5156	95	10	,	,	PUNCT
fnp-5156	95	11	mcgbm_mes_atyp	mcgbm_mes_atyp	X
fnp-5156	95	12	(	(	PUNCT
fnp-5156	95	13	17/2	17/2	NUM
fnp-5156	95	14	)	)	PUNCT
fnp-5156	95	15	and	and	CCONJ
fnp-5156	95	16	mc	mc	PROPN
fnp-5156	95	17	malignant	malignant	ADJ
fnp-5156	95	18	peripheral	peripheral	ADJ
fnp-5156	95	19	nerve	nerve	NOUN
fnp-5156	95	20	sheath	sheath	NOUN
fnp-5156	95	21	tumor	tumor	NOUN
fnp-5156	95	22	(	(	PUNCT
fnp-5156	95	23	mcmpnst	mcmpnst	PROPN
fnp-5156	95	24	)	)	PUNCT
fnp-5156	95	25	(	(	PUNCT
fnp-5156	95	26	6/2	6/2	NUM
fnp-5156	95	27	)	)	PUNCT
fnp-5156	95	28	.	.	PUNCT
fnp-5156	96	1	all	all	DET
fnp-5156	96	2	predictions	prediction	NOUN
fnp-5156	96	3	for	for	ADP
fnp-5156	96	4	the	the	DET
fnp-5156	96	5	551	551	NUM
fnp-5156	96	6	tumors	tumor	NOUN
fnp-5156	96	7	are	be	AUX
fnp-5156	96	8	listed	list	VERB
fnp-5156	96	9	in	in	ADP
fnp-5156	96	10	supplementary	supplementary	ADJ
fnp-5156	96	11	table	table	NOUN
fnp-5156	96	12	1	1	NUM
fnp-5156	96	13	.	.	PUNCT
fnp-5156	96	14	as	as	SCONJ
fnp-5156	96	15	expected	expect	VERB
fnp-5156	96	16	,	,	PUNCT
fnp-5156	96	17	a	a	DET
fnp-5156	96	18	substantial	substantial	ADJ
fnp-5156	96	19	portion	portion	NOUN
fnp-5156	96	20	of	of	ADP
fnp-5156	96	21	tumors	tumor	NOUN
fnp-5156	96	22	with	with	ADP
fnp-5156	96	23	a	a	DET
fnp-5156	96	24	histological	histological	ADJ
fnp-5156	96	25	pxa	pxa	NOUN
fnp-5156	96	26	diagnosis	diagnosis	NOUN
fnp-5156	96	27	or	or	CCONJ
fnp-5156	96	28	suspicion	suspicion	NOUN
fnp-5156	96	29	received	receive	VERB
fnp-5156	96	30	a	a	DET
fnp-5156	96	31	prediction	prediction	NOUN
fnp-5156	96	32	for	for	ADP
fnp-5156	96	33	glioblastoma	glioblastoma	NOUN
fnp-5156	96	34	.	.	PUNCT
fnp-5156	97	1	surprising	surprising	ADJ
fnp-5156	97	2	was	be	AUX
fnp-5156	97	3	the	the	DET
fnp-5156	97	4	distribution	distribution	NOUN
fnp-5156	97	5	among	among	ADP
fnp-5156	97	6	the	the	DET
fnp-5156	97	7	four	four	NUM
fnp-5156	97	8	adult	adult	NOUN
fnp-5156	97	9	glioblastoma	glioblastoma	NOUN
fnp-5156	97	10	subclasses	subclass	NOUN
fnp-5156	97	11	.	.	PUNCT
fnp-5156	98	1	the	the	DET
fnp-5156	98	2	mcgbm_mes_typ	mcgbm_mes_typ	NOUN
fnp-5156	98	3	was	be	AUX
fnp-5156	98	4	predicted	predict	VERB
fnp-5156	98	5	with	with	ADP
fnp-5156	98	6	high	high	ADJ
fnp-5156	98	7	score	score	NOUN
fnp-5156	98	8	in	in	ADP
fnp-5156	98	9	62	62	NUM
fnp-5156	98	10	,	,	PUNCT
fnp-5156	98	11	mcgbm_mes_atyp	mcgbm_mes_atyp	VERB
fnp-5156	98	12	in	in	ADP
fnp-5156	98	13	5	5	NUM
fnp-5156	98	14	,	,	PUNCT
fnp-5156	98	15	mcgbm_rtk2	mcgbm_rtk2	NOUN
fnp-5156	98	16	in	in	ADP
fnp-5156	98	17	6	6	NUM
fnp-5156	98	18	and	and	CCONJ
fnp-5156	98	19	mcgbm_rtk1	mcgbm_rtk1	NOUN
fnp-5156	98	20	in	in	ADP
fnp-5156	98	21	3	3	NUM
fnp-5156	98	22	tumors	tumor	NOUN
fnp-5156	98	23	.	.	PUNCT
fnp-5156	99	1	this	this	PRON
fnp-5156	99	2	is	be	AUX
fnp-5156	99	3	suggestive	suggestive	ADJ
fnp-5156	99	4	of	of	ADP
fnp-5156	99	5	shared	share	VERB
fnp-5156	99	6	histological	histological	ADJ
fnp-5156	99	7	features	feature	NOUN
fnp-5156	99	8	of	of	ADP
fnp-5156	99	9	pxa	pxa	NOUN
fnp-5156	99	10	with	with	ADP
fnp-5156	99	11	gbm	gbm	PROPN
fnp-5156	99	12	belonging	belong	VERB
fnp-5156	99	13	to	to	ADP
fnp-5156	99	14	the	the	DET
fnp-5156	99	15	mcgbm_mes_typ	mcgbm_mes_typ	NOUN
fnp-5156	99	16	.	.	NOUN
fnp-5156	99	17	pxa	pxa	NOUN
fnp-5156	99	18	with	with	ADP
fnp-5156	99	19	predictions	prediction	NOUN
fnp-5156	99	20	other	other	ADJ
fnp-5156	99	21	than	than	ADP
fnp-5156	99	22	mcpxa	mcpxa	NOUN
fnp-5156	99	23	and	and	CCONJ
fnp-5156	99	24	calibrated	calibrate	VERB
fnp-5156	99	25	scores	score	NOUN
fnp-5156	99	26	>	>	X
fnp-5156	99	27	0.9	0.9	NUM
fnp-5156	99	28	clustered	cluster	VERB
fnp-5156	99	29	well	well	ADV
fnp-5156	99	30	with	with	ADP
fnp-5156	99	31	the	the	DET
fnp-5156	99	32	respective	respective	ADJ
fnp-5156	99	33	reference	reference	NOUN
fnp-5156	99	34	groups	group	NOUN
fnp-5156	99	35	(	(	PUNCT
fnp-5156	99	36	figure	figure	VERB
fnp-5156	99	37	4	4	NUM
fnp-5156	99	38	)	)	PUNCT
fnp-5156	99	39	.	.	PUNCT
fnp-5156	100	1	pxa	pxa	NOUN
fnp-5156	100	2	with	with	ADP
fnp-5156	100	3	predictions	prediction	NOUN
fnp-5156	100	4	other	other	ADJ
fnp-5156	100	5	than	than	ADP
fnp-5156	100	6	mcpxa	mcpxa	NOUN
fnp-5156	100	7	and	and	CCONJ
fnp-5156	100	8	calibrated	calibrate	VERB
fnp-5156	100	9	scores	score	NOUN
fnp-5156	100	10	<	<	X
fnp-5156	100	11	0.9	0.9	NUM
fnp-5156	100	12	exhibited	exhibit	VERB
fnp-5156	100	13	a	a	DET
fnp-5156	100	14	scattered	scatter	VERB
fnp-5156	100	15	distribution	distribution	NOUN
fnp-5156	100	16	(	(	PUNCT
fnp-5156	100	17	data	datum	NOUN
fnp-5156	100	18	not	not	PART
fnp-5156	100	19	shown	show	VERB
fnp-5156	100	20	)	)	PUNCT
fnp-5156	100	21	.	.	PUNCT
fnp-5156	101	1	figure	figure	VERB
fnp-5156	101	2	4	4	NUM
fnp-5156	101	3	:	:	PUNCT
fnp-5156	101	4	tsne	tsne	VERB
fnp-5156	101	5	analysis	analysis	NOUN
fnp-5156	101	6	of	of	ADP
fnp-5156	101	7	tumors	tumor	NOUN
fnp-5156	101	8	diagnosed	diagnose	VERB
fnp-5156	101	9	as	as	ADP
fnp-5156	101	10	pxa	pxa	NOUN
fnp-5156	101	11	receiving	receive	VERB
fnp-5156	101	12	a	a	DET
fnp-5156	101	13	calibrated	calibrate	VERB
fnp-5156	101	14	score	score	NOUN
fnp-5156	101	15	>	>	X
fnp-5156	101	16	0.9	0.9	NUM
fnp-5156	101	17	,	,	PUNCT
fnp-5156	101	18	and	and	CCONJ
fnp-5156	101	19	reference	reference	NOUN
fnp-5156	101	20	sets	set	NOUN
fnp-5156	101	21	.	.	PUNCT
fnp-5156	102	1	tumors	tumor	NOUN
fnp-5156	102	2	not	not	PART
fnp-5156	102	3	receiving	receive	VERB
fnp-5156	102	4	a	a	DET
fnp-5156	102	5	mcpxa	mcpxa	NOUN
fnp-5156	102	6	prediction	prediction	NOUN
fnp-5156	102	7	cluster	cluster	NOUN
fnp-5156	102	8	with	with	ADP
fnp-5156	102	9	the	the	DET
fnp-5156	102	10	respective	respective	ADJ
fnp-5156	102	11	reference	reference	NOUN
fnp-5156	102	12	groups	group	NOUN
fnp-5156	102	13	.	.	PUNCT
fnp-5156	103	1	parameters	parameter	NOUN
fnp-5156	103	2	:	:	PUNCT
fnp-5156	103	3	tsne_cpgs_20000_perplexities_10_iter_3000_theta_0_eta_200_dim_2	tsne_cpgs_20000_perplexities_10_iter_3000_theta_0_eta_200_dim_2	ADJ
fnp-5156	103	4	discussion	discussion	NOUN
fnp-5156	103	5	one	one	NUM
fnp-5156	103	6	major	major	ADJ
fnp-5156	103	7	weakness	weakness	NOUN
fnp-5156	103	8	of	of	ADP
fnp-5156	103	9	the	the	DET
fnp-5156	103	10	present	present	ADJ
fnp-5156	103	11	study	study	NOUN
fnp-5156	103	12	concerns	concern	VERB
fnp-5156	103	13	the	the	DET
fnp-5156	103	14	available	available	ADJ
fnp-5156	103	15	data	datum	NOUN
fnp-5156	103	16	on	on	ADP
fnp-5156	103	17	histological	histological	ADJ
fnp-5156	103	18	diagnoses	diagnosis	NOUN
fnp-5156	103	19	of	of	ADP
fnp-5156	103	20	the	the	DET
fnp-5156	103	21	extended	extended	ADJ
fnp-5156	103	22	cohort	cohort	NOUN
fnp-5156	103	23	(	(	PUNCT
fnp-5156	103	24	supplementary	supplementary	ADJ
fnp-5156	103	25	table	table	NOUN
fnp-5156	103	26	2	2	NUM
fnp-5156	103	27	)	)	PUNCT
fnp-5156	103	28	.	.	PUNCT
fnp-5156	104	1	for	for	ADP
fnp-5156	104	2	386/932	386/932	NUM
fnp-5156	104	3	tumors	tumor	NOUN
fnp-5156	104	4	with	with	ADP
fnp-5156	104	5	a	a	DET
fnp-5156	104	6	mcpxa	mcpxa	NOUN
fnp-5156	104	7	prediction	prediction	NOUN
fnp-5156	104	8	no	no	DET
fnp-5156	104	9	sufficiently	sufficiently	ADV
fnp-5156	104	10	specified	specify	VERB
fnp-5156	104	11	diagnosis	diagnosis	NOUN
fnp-5156	104	12	was	be	AUX
fnp-5156	104	13	given	give	VERB
fnp-5156	104	14	.	.	PUNCT
fnp-5156	105	1	submitters	submitter	NOUN
fnp-5156	105	2	of	of	ADP
fnp-5156	105	3	data	datum	NOUN
fnp-5156	105	4	to	to	ADP
fnp-5156	105	5	the	the	DET
fnp-5156	105	6	webpage	webpage	NOUN
fnp-5156	105	7	may	may	AUX
fnp-5156	105	8	have	have	AUX
fnp-5156	105	9	been	be	AUX
fnp-5156	105	10	inexperienced	inexperience	VERB
fnp-5156	105	11	,	,	PUNCT
fnp-5156	105	12	may	may	AUX
fnp-5156	105	13	have	have	AUX
fnp-5156	105	14	been	be	AUX
fnp-5156	105	15	not	not	PART
fnp-5156	105	16	overly	overly	ADV
fnp-5156	105	17	motivated	motivated	ADJ
fnp-5156	105	18	to	to	PART
fnp-5156	105	19	provide	provide	VERB
fnp-5156	105	20	the	the	DET
fnp-5156	105	21	(	(	PUNCT
fnp-5156	105	22	optional	optional	ADJ
fnp-5156	105	23	)	)	PUNCT
fnp-5156	105	24	information	information	NOUN
fnp-5156	105	25	or	or	CCONJ
fnp-5156	105	26	may	may	AUX
fnp-5156	105	27	have	have	AUX
fnp-5156	105	28	uploaded	upload	VERB
fnp-5156	105	29	data	datum	NOUN
fnp-5156	105	30	prior	prior	ADV
fnp-5156	105	31	to	to	ADP
fnp-5156	105	32	finalization	finalization	NOUN
fnp-5156	105	33	of	of	ADP
fnp-5156	105	34	the	the	DET
fnp-5156	105	35	diagnosis	diagnosis	NOUN
fnp-5156	105	36	.	.	PUNCT
fnp-5156	106	1	the	the	DET
fnp-5156	106	2	webpage	webpage	NOUN
fnp-5156	106	3	serving	serve	VERB
fnp-5156	106	4	as	as	ADP
fnp-5156	106	5	a	a	DET
fnp-5156	106	6	basis	basis	NOUN
fnp-5156	106	7	for	for	ADP
fnp-5156	106	8	the	the	DET
fnp-5156	106	9	study	study	NOUN
fnp-5156	106	10	does	do	AUX
fnp-5156	106	11	not	not	PART
fnp-5156	106	12	allow	allow	VERB
fnp-5156	106	13	for	for	ADP
fnp-5156	106	14	submitting	submit	VERB
fnp-5156	106	15	a	a	DET
fnp-5156	106	16	revised	revise	VERB
fnp-5156	106	17	version	version	NOUN
fnp-5156	106	18	of	of	ADP
fnp-5156	106	19	the	the	DET
fnp-5156	106	20	diagnosis	diagnosis	NOUN
fnp-5156	106	21	upon	upon	SCONJ
fnp-5156	106	22	completion	completion	NOUN
fnp-5156	106	23	of	of	ADP
fnp-5156	106	24	methylation	methylation	NOUN
fnp-5156	106	25	analysis	analysis	NOUN
fnp-5156	106	26	.	.	PUNCT
fnp-5156	107	1	a	a	DET
fnp-5156	107	2	review	review	NOUN
fnp-5156	107	3	of	of	ADP
fnp-5156	107	4	the	the	DET
fnp-5156	107	5	diagnoses	diagnosis	NOUN
fnp-5156	107	6	is	be	AUX
fnp-5156	107	7	unfortunately	unfortunately	ADV
fnp-5156	107	8	not	not	PART
fnp-5156	107	9	possible	possible	ADJ
fnp-5156	107	10	.	.	PUNCT
fnp-5156	108	1	therefore	therefore	ADV
fnp-5156	108	2	,	,	PUNCT
fnp-5156	108	3	we	we	PRON
fnp-5156	108	4	assume	assume	VERB
fnp-5156	108	5	that	that	SCONJ
fnp-5156	108	6	many	many	ADJ
fnp-5156	108	7	of	of	ADP
fnp-5156	108	8	the	the	DET
fnp-5156	108	9	tumors	tumor	NOUN
fnp-5156	108	10	which	which	PRON
fnp-5156	108	11	received	receive	VERB
fnp-5156	108	12	a	a	DET
fnp-5156	108	13	prediction	prediction	NOUN
fnp-5156	108	14	mcpxa	mcpxa	NOUN
fnp-5156	108	15	also	also	ADV
fnp-5156	108	16	would	would	AUX
fnp-5156	108	17	have	have	AUX
fnp-5156	108	18	received	receive	VERB
fnp-5156	108	19	the	the	DET
fnp-5156	108	20	histological	histological	ADJ
fnp-5156	108	21	classification	classification	NOUN
fnp-5156	108	22	pxa	pxa	NOUN
fnp-5156	108	23	.	.	PUNCT
fnp-5156	109	1	this	this	DET
fnp-5156	109	2	very	very	ADV
fnp-5156	109	3	large	large	ADJ
fnp-5156	109	4	tumor	tumor	NOUN
fnp-5156	109	5	series	series	NOUN
fnp-5156	109	6	,	,	PUNCT
fnp-5156	109	7	however	however	ADV
fnp-5156	109	8	,	,	PUNCT
fnp-5156	109	9	allows	allow	VERB
fnp-5156	109	10	drawing	drawing	NOUN
fnp-5156	109	11	of	of	ADP
fnp-5156	109	12	two	two	NUM
fnp-5156	109	13	main	main	ADJ
fnp-5156	109	14	conclusions	conclusion	NOUN
fnp-5156	109	15	:	:	PUNCT
fnp-5156	109	16	399/932	399/932	NUM
fnp-5156	109	17	tumors	tumor	NOUN
fnp-5156	109	18	with	with	ADP
fnp-5156	109	19	a	a	DET
fnp-5156	109	20	clear	clear	ADJ
fnp-5156	109	21	molecular	molecular	ADJ
fnp-5156	109	22	pattern	pattern	NOUN
fnp-5156	109	23	(	(	PUNCT
fnp-5156	109	24	dna	dna	NOUN
fnp-5156	109	25	methylation	methylation	NOUN
fnp-5156	109	26	and	and	CCONJ
fnp-5156	109	27	cnv	cnv	PROPN
fnp-5156	109	28	profile	profile	NOUN
fnp-5156	109	29	)	)	PUNCT
fnp-5156	109	30	of	of	ADP
fnp-5156	109	31	pxa	pxa	NOUN
fnp-5156	109	32	received	receive	VERB
fnp-5156	109	33	a	a	DET
fnp-5156	109	34	non	non	ADJ
fnp-5156	109	35	-	-	ADJ
fnp-5156	109	36	pxa	pxa	ADJ
fnp-5156	109	37	histological	histological	ADJ
fnp-5156	109	38	diagnosis	diagnosis	NOUN
fnp-5156	109	39	suggesting	suggest	VERB
fnp-5156	109	40	a	a	DET
fnp-5156	109	41	high	high	ADJ
fnp-5156	109	42	morphological	morphological	ADJ
fnp-5156	109	43	variance	variance	NOUN
fnp-5156	109	44	in	in	ADP
fnp-5156	109	45	mcpxa	mcpxa	NOUN
fnp-5156	109	46	that	that	PRON
fnp-5156	109	47	precluded	preclude	VERB
fnp-5156	109	48	a	a	DET
fnp-5156	109	49	histological	histological	ADJ
fnp-5156	109	50	pxa	pxa	NOUN
fnp-5156	109	51	diagnosis	diagnosis	NOUN
fnp-5156	109	52	in	in	ADP
fnp-5156	109	53	at	at	ADV
fnp-5156	109	54	least	least	ADV
fnp-5156	109	55	43	43	NUM
fnp-5156	109	56	%	%	NOUN
fnp-5156	109	57	and	and	CCONJ
fnp-5156	109	58	up	up	ADP
fnp-5156	109	59	to	to	PART
fnp-5156	109	60	82	82	NUM
fnp-5156	109	61	%	%	NOUN
fnp-5156	109	62	of	of	ADP
fnp-5156	109	63	the	the	DET
fnp-5156	109	64	cases	case	NOUN
fnp-5156	109	65	(	(	PUNCT
fnp-5156	109	66	depending	depend	VERB
fnp-5156	109	67	on	on	ADP
fnp-5156	109	68	scoring	scoring	NOUN
fnp-5156	109	69	of	of	ADP
fnp-5156	109	70	the	the	DET
fnp-5156	109	71	386	386	NUM
fnp-5156	109	72	tumors	tumor	NOUN
fnp-5156	109	73	without	without	ADP
fnp-5156	109	74	a	a	DET
fnp-5156	109	75	diagnosis	diagnosis	NOUN
fnp-5156	109	76	at	at	ADV
fnp-5156	109	77	all	all	ADV
fnp-5156	109	78	)	)	PUNCT
fnp-5156	109	79	.	.	PUNCT
fnp-5156	110	1	a	a	DET
fnp-5156	110	2	conservative	conservative	ADJ
fnp-5156	110	3	estimate	estimate	NOUN
fnp-5156	110	4	would	would	AUX
fnp-5156	110	5	therefore	therefore	ADV
fnp-5156	110	6	estimate	estimate	VERB
fnp-5156	110	7	that	that	SCONJ
fnp-5156	110	8	~50	~50	ADP
fnp-5156	110	9	%	%	NOUN
fnp-5156	110	10	of	of	ADP
fnp-5156	110	11	mcpxa	mcpxa	NOUN
fnp-5156	110	12	will	will	AUX
fnp-5156	110	13	not	not	PART
fnp-5156	110	14	be	be	AUX
fnp-5156	110	15	recognized	recognize	VERB
fnp-5156	110	16	by	by	ADP
fnp-5156	110	17	histology	histology	NOUN
fnp-5156	110	18	alone	alone	ADV
fnp-5156	110	19	.	.	PUNCT
fnp-5156	111	1	the	the	DET
fnp-5156	111	2	other	other	ADJ
fnp-5156	111	3	conclusion	conclusion	NOUN
fnp-5156	111	4	is	be	AUX
fnp-5156	111	5	that	that	SCONJ
fnp-5156	111	6	the	the	DET
fnp-5156	111	7	165	165	NUM
fnp-5156	111	8	tumors	tumor	NOUN
fnp-5156	111	9	with	with	ADP
fnp-5156	111	10	both	both	CCONJ
fnp-5156	111	11	a	a	DET
fnp-5156	111	12	pxa	pxa	NOUN
fnp-5156	111	13	diagnosis	diagnosis	NOUN
fnp-5156	111	14	as	as	ADV
fnp-5156	111	15	well	well	ADV
fnp-5156	111	16	as	as	ADP
fnp-5156	111	17	a	a	DET
fnp-5156	111	18	mcpxa	mcpxa	NOUN
fnp-5156	111	19	prediction	prediction	NOUN
fnp-5156	111	20	is	be	AUX
fnp-5156	111	21	large	large	ADJ
fnp-5156	111	22	enough	enough	ADV
fnp-5156	111	23	for	for	ADP
fnp-5156	111	24	serving	serve	VERB
fnp-5156	111	25	as	as	ADP
fnp-5156	111	26	a	a	DET
fnp-5156	111	27	‘	'	PUNCT
fnp-5156	111	28	standard	standard	ADJ
fnp-5156	111	29	’	'	PUNCT
fnp-5156	111	30	reference	reference	NOUN
fnp-5156	111	31	set	set	VERB
fnp-5156	111	32	for	for	ADP
fnp-5156	111	33	subsequent	subsequent	ADJ
fnp-5156	111	34	comparisons	comparison	NOUN
fnp-5156	111	35	with	with	ADP
fnp-5156	111	36	the	the	DET
fnp-5156	111	37	762	762	NUM
fnp-5156	111	38	mcpxa	mcpxa	NOUN
fnp-5156	111	39	not	not	PART
fnp-5156	111	40	having	having	AUX
fnp-5156	111	41	received	receive	VERB
fnp-5156	111	42	a	a	DET
fnp-5156	111	43	pxa	pxa	NOUN
fnp-5156	111	44	diagnosis	diagnosis	NOUN
fnp-5156	111	45	.	.	PUNCT
fnp-5156	112	1	tumors	tumor	NOUN
fnp-5156	112	2	with	with	ADP
fnp-5156	112	3	mcpxa	mcpxa	NOUN
fnp-5156	112	4	prediction	prediction	NOUN
fnp-5156	112	5	are	be	AUX
fnp-5156	112	6	highly	highly	ADV
fnp-5156	112	7	homogenous	homogenous	ADJ
fnp-5156	112	8	in	in	ADP
fnp-5156	112	9	respect	respect	NOUN
fnp-5156	112	10	to	to	ADP
fnp-5156	112	11	grouping	group	VERB
fnp-5156	112	12	upon	upon	SCONJ
fnp-5156	112	13	tsne	tsne	NOUN
fnp-5156	112	14	analyses	analysis	NOUN
fnp-5156	112	15	or	or	CCONJ
fnp-5156	112	16	cnv	cnv	NOUN
fnp-5156	112	17	analyses	analysis	NOUN
fnp-5156	112	18	independent	independent	ADJ
fnp-5156	112	19	of	of	ADP
fnp-5156	112	20	whether	whether	SCONJ
fnp-5156	112	21	they	they	PRON
fnp-5156	112	22	were	be	AUX
fnp-5156	112	23	histologically	histologically	ADV
fnp-5156	112	24	diagnosed	diagnose	VERB
fnp-5156	112	25	as	as	ADP
fnp-5156	112	26	pxa	pxa	NOUN
fnp-5156	112	27	or	or	CCONJ
fnp-5156	112	28	as	as	ADP
fnp-5156	112	29	other	other	ADJ
fnp-5156	112	30	tumors	tumor	NOUN
fnp-5156	112	31	(	(	PUNCT
fnp-5156	112	32	figures	figure	NOUN
fnp-5156	112	33	2	2	NUM
fnp-5156	112	34	and	and	CCONJ
fnp-5156	112	35	3	3	NUM
fnp-5156	112	36	,	,	PUNCT
fnp-5156	112	37	tables	table	NOUN
fnp-5156	112	38	1	1	NUM
fnp-5156	112	39	and	and	CCONJ
fnp-5156	112	40	2	2	NUM
fnp-5156	112	41	)	)	PUNCT
fnp-5156	112	42	.	.	PUNCT
fnp-5156	113	1	this	this	PRON
fnp-5156	113	2	includes	include	VERB
fnp-5156	113	3	all	all	DET
fnp-5156	113	4	methylation	methylation	NOUN
fnp-5156	113	5	patterns	pattern	NOUN
fnp-5156	113	6	,	,	PUNCT
fnp-5156	113	7	gains	gain	NOUN
fnp-5156	113	8	and	and	CCONJ
fnp-5156	113	9	losses	loss	NOUN
fnp-5156	113	10	of	of	ADP
fnp-5156	113	11	chromosomal	chromosomal	ADJ
fnp-5156	113	12	arms	arm	NOUN
fnp-5156	113	13	as	as	ADV
fnp-5156	113	14	well	well	ADV
fnp-5156	113	15	as	as	ADP
fnp-5156	113	16	circumscribed	circumscribed	ADJ
fnp-5156	113	17	amplifications	amplification	NOUN
fnp-5156	113	18	or	or	CCONJ
fnp-5156	113	19	homozygous	homozygous	ADJ
fnp-5156	113	20	deletions	deletion	NOUN
fnp-5156	113	21	.	.	PUNCT
fnp-5156	114	1	in	in	ADP
fnp-5156	114	2	contrast	contrast	NOUN
fnp-5156	114	3	,	,	PUNCT
fnp-5156	114	4	tumors	tumor	NOUN
fnp-5156	114	5	diagnosed	diagnose	VERB
fnp-5156	114	6	as	as	ADP
fnp-5156	114	7	pxa	pxa	NOUN
fnp-5156	114	8	on	on	ADP
fnp-5156	114	9	histologic	histologic	ADJ
fnp-5156	114	10	grounds	ground	NOUN
fnp-5156	114	11	alone	alone	ADV
fnp-5156	114	12	were	be	AUX
fnp-5156	114	13	heterogeneous	heterogeneous	ADJ
fnp-5156	114	14	upon	upon	SCONJ
fnp-5156	114	15	tsne	tsne	NOUN
fnp-5156	114	16	(	(	PUNCT
fnp-5156	114	17	figure	figure	NOUN
fnp-5156	114	18	4	4	NUM
fnp-5156	114	19	)	)	PUNCT
fnp-5156	114	20	and	and	CCONJ
fnp-5156	114	21	cnv	cnv	PROPN
fnp-5156	114	22	analyses	analysis	NOUN
fnp-5156	114	23	(	(	PUNCT
fnp-5156	114	24	supplementary	supplementary	ADJ
fnp-5156	114	25	tables	table	NOUN
fnp-5156	114	26	3	3	NUM
fnp-5156	114	27	and	and	CCONJ
fnp-5156	114	28	4	4	NUM
fnp-5156	114	29	)	)	PUNCT
fnp-5156	114	30	.	.	PUNCT
fnp-5156	115	1	histologically	histologically	ADV
fnp-5156	115	2	diagnosed	diagnose	VERB
fnp-5156	115	3	pxa	pxa	NOUN
fnp-5156	115	4	with	with	ADP
fnp-5156	115	5	non	non	ADJ
fnp-5156	115	6	mcpxa	mcpxa	PROPN
fnp-5156	115	7	classifier	classifier	PROPN
fnp-5156	115	8	prediction	prediction	PROPN
fnp-5156	115	9	exhibited	exhibited	AUX
fnp-5156	115	10	copy	copy	NOUN
fnp-5156	115	11	number	number	NOUN
fnp-5156	115	12	alterations	alteration	NOUN
fnp-5156	115	13	corresponding	correspond	VERB
fnp-5156	115	14	to	to	ADP
fnp-5156	115	15	those	those	PRON
fnp-5156	115	16	seen	see	VERB
fnp-5156	115	17	in	in	ADP
fnp-5156	115	18	the	the	DET
fnp-5156	115	19	respective	respective	ADJ
fnp-5156	115	20	methylation	methylation	NOUN
fnp-5156	115	21	classes	class	NOUN
fnp-5156	115	22	.	.	PUNCT
fnp-5156	116	1	this	this	DET
fnp-5156	116	2	data	data	NOUN
fnp-5156	116	3	constellation	constellation	NOUN
fnp-5156	116	4	is	be	AUX
fnp-5156	116	5	compatible	compatible	ADJ
fnp-5156	116	6	with	with	ADP
fnp-5156	116	7	a	a	DET
fnp-5156	116	8	model	model	NOUN
fnp-5156	116	9	assuming	assume	VERB
fnp-5156	116	10	that	that	SCONJ
fnp-5156	116	11	a	a	DET
fnp-5156	116	12	classifier	classifier	NOUN
fnp-5156	116	13	-	-	PUNCT
fnp-5156	116	14	based	base	VERB
fnp-5156	116	15	approach	approach	NOUN
fnp-5156	116	16	predicting	predict	VERB
fnp-5156	116	17	mcpxa	mcpxa	NOUN
fnp-5156	116	18	is	be	AUX
fnp-5156	116	19	recognizing	recognize	VERB
fnp-5156	116	20	a	a	DET
fnp-5156	116	21	tumor	tumor	NOUN
fnp-5156	116	22	cohort	cohort	NOUN
fnp-5156	116	23	more	more	ADV
fnp-5156	116	24	homogenous	homogenous	ADJ
fnp-5156	116	25	than	than	ADP
fnp-5156	116	26	a	a	DET
fnp-5156	116	27	histology	histology	NOUN
fnp-5156	116	28	-	-	PUNCT
fnp-5156	116	29	based	base	VERB
fnp-5156	116	30	approach	approach	NOUN
fnp-5156	116	31	diagnosing	diagnose	VERB
fnp-5156	116	32	pxa	pxa	NOUN
fnp-5156	116	33	.	.	PUNCT
fnp-5156	117	1	based	base	VERB
fnp-5156	117	2	on	on	ADP
fnp-5156	117	3	the	the	DET
fnp-5156	117	4	high	high	ADJ
fnp-5156	117	5	homogeneity	homogeneity	NOUN
fnp-5156	117	6	of	of	ADP
fnp-5156	117	7	mcpxa	mcpxa	NOUN
fnp-5156	117	8	and	and	CCONJ
fnp-5156	117	9	mcpxaref	mcpxaref	ADV
fnp-5156	117	10	this	this	DET
fnp-5156	117	11	study	study	NOUN
fnp-5156	117	12	provides	provide	VERB
fnp-5156	117	13	a	a	DET
fnp-5156	117	14	stable	stable	ADJ
fnp-5156	117	15	framework	framework	NOUN
fnp-5156	117	16	for	for	ADP
fnp-5156	117	17	cnv	cnv	PROPN
fnp-5156	117	18	alterations	alteration	NOUN
fnp-5156	117	19	.	.	PUNCT
fnp-5156	118	1	this	this	PRON
fnp-5156	118	2	is	be	AUX
fnp-5156	118	3	of	of	ADP
fnp-5156	118	4	relevance	relevance	NOUN
fnp-5156	118	5	for	for	ADP
fnp-5156	118	6	separating	separate	VERB
fnp-5156	118	7	pxa	pxa	NOUN
fnp-5156	118	8	from	from	ADP
fnp-5156	118	9	gbm	gbm	PROPN
fnp-5156	118	10	.	.	PUNCT
fnp-5156	119	1	the	the	DET
fnp-5156	119	2	7/10	7/10	NUM
fnp-5156	119	3	signature	signature	NOUN
fnp-5156	119	4	has	have	AUX
fnp-5156	119	5	been	be	AUX
fnp-5156	119	6	proposed	propose	VERB
fnp-5156	119	7	by	by	ADP
fnp-5156	119	8	who	who	PRON
fnp-5156	119	9	as	as	ADP
fnp-5156	119	10	a	a	DET
fnp-5156	119	11	surrogate	surrogate	ADJ
fnp-5156	119	12	marker	marker	NOUN
fnp-5156	119	13	for	for	ADP
fnp-5156	119	14	gbm	gbm	ADJ
fnp-5156	119	15	diagnosis	diagnosis	NOUN
fnp-5156	119	16	in	in	ADP
fnp-5156	119	17	absence	absence	NOUN
fnp-5156	119	18	of	of	ADP
fnp-5156	119	19	necrosis	necrosis	NOUN
fnp-5156	119	20	or	or	CCONJ
fnp-5156	119	21	microvascular	microvascular	ADJ
fnp-5156	119	22	proliferation	proliferation	NOUN
fnp-5156	119	23	.	.	PUNCT
fnp-5156	120	1	the	the	DET
fnp-5156	120	2	present	present	ADJ
fnp-5156	120	3	data	datum	NOUN
fnp-5156	120	4	demonstrate	demonstrate	VERB
fnp-5156	120	5	that	that	SCONJ
fnp-5156	120	6	the	the	DET
fnp-5156	120	7	7/10	7/10	NUM
fnp-5156	120	8	signature	signature	NOUN
fnp-5156	120	9	is	be	AUX
fnp-5156	120	10	present	present	ADJ
fnp-5156	120	11	in	in	ADP
fnp-5156	120	12	15	15	NUM
fnp-5156	120	13	%	%	NOUN
fnp-5156	120	14	to	to	PART
fnp-5156	120	15	20	20	NUM
fnp-5156	120	16	%	%	NOUN
fnp-5156	120	17	of	of	ADP
fnp-5156	120	18	mcpxa	mcpxa	NOUN
fnp-5156	120	19	,	,	PUNCT
fnp-5156	120	20	suggesting	suggest	VERB
fnp-5156	120	21	caution	caution	NOUN
fnp-5156	120	22	is	be	AUX
fnp-5156	120	23	advised	advise	VERB
fnp-5156	120	24	when	when	SCONJ
fnp-5156	120	25	considering	consider	VERB
fnp-5156	120	26	this	this	PRON
fnp-5156	120	27	as	as	ADP
fnp-5156	120	28	a	a	DET
fnp-5156	120	29	sole	sole	ADJ
fnp-5156	120	30	marker	marker	NOUN
fnp-5156	120	31	.	.	PUNCT
fnp-5156	121	1	this	this	PRON
fnp-5156	121	2	must	must	AUX
fnp-5156	121	3	be	be	AUX
fnp-5156	121	4	balanced	balance	VERB
fnp-5156	121	5	against	against	ADP
fnp-5156	121	6	the	the	DET
fnp-5156	121	7	clear	clear	ADJ
fnp-5156	121	8	value	value	NOUN
fnp-5156	121	9	of	of	ADP
fnp-5156	121	10	the	the	DET
fnp-5156	121	11	7/10	7/10	NUM
fnp-5156	121	12	signature	signature	NOUN
fnp-5156	121	13	especially	especially	ADV
fnp-5156	121	14	in	in	ADP
fnp-5156	121	15	tissue	tissue	NOUN
fnp-5156	121	16	specimens	specimen	NOUN
fnp-5156	121	17	from	from	ADP
fnp-5156	121	18	the	the	DET
fnp-5156	121	19	tumor	tumor	NOUN
fnp-5156	121	20	edges	edge	NOUN
fnp-5156	121	21	or	or	CCONJ
fnp-5156	121	22	from	from	ADP
fnp-5156	121	23	stereotactic	stereotactic	ADJ
fnp-5156	121	24	biopsies	biopsy	NOUN
fnp-5156	121	25	in	in	ADP
fnp-5156	121	26	elderly	elderly	ADJ
fnp-5156	121	27	patients	patient	NOUN
fnp-5156	121	28	.	.	PUNCT
fnp-5156	122	1	amplifications	amplification	NOUN
fnp-5156	122	2	of	of	ADP
fnp-5156	122	3	egfr	egfr	NOUN
fnp-5156	122	4	,	,	PUNCT
fnp-5156	122	5	mdm2	mdm2	PROPN
fnp-5156	122	6	and	and	CCONJ
fnp-5156	122	7	pdgfra	pdgfra	NOUN
fnp-5156	122	8	occurred	occur	VERB
fnp-5156	122	9	in	in	ADP
fnp-5156	122	10	9/932	9/932	NUM
fnp-5156	122	11	(	(	PUNCT
fnp-5156	122	12	<	<	X
fnp-5156	122	13	1	1	NUM
fnp-5156	122	14	%	%	NOUN
fnp-5156	122	15	)	)	PUNCT
fnp-5156	122	16	mcpxa	mcpxa	NOUN
fnp-5156	122	17	(	(	PUNCT
fnp-5156	122	18	table	table	NOUN
fnp-5156	122	19	2	2	NUM
fnp-5156	122	20	)	)	PUNCT
fnp-5156	122	21	.	.	PUNCT
fnp-5156	123	1	in	in	ADP
fnp-5156	123	2	contrast	contrast	NOUN
fnp-5156	123	3	,	,	PUNCT
fnp-5156	123	4	gene	gene	NOUN
fnp-5156	123	5	amplifications	amplification	NOUN
fnp-5156	123	6	are	be	AUX
fnp-5156	123	7	highly	highly	ADV
fnp-5156	123	8	prevalent	prevalent	ADJ
fnp-5156	123	9	in	in	ADP
fnp-5156	123	10	gbm	gbm	NOUN
fnp-5156	123	11	,	,	PUNCT
fnp-5156	123	12	although	although	SCONJ
fnp-5156	123	13	there	there	PRON
fnp-5156	123	14	appear	appear	VERB
fnp-5156	123	15	to	to	PART
fnp-5156	123	16	be	be	AUX
fnp-5156	123	17	methylation	methylation	NOUN
fnp-5156	123	18	class	class	NOUN
fnp-5156	123	19	specific	specific	ADJ
fnp-5156	123	20	differences	difference	NOUN
fnp-5156	123	21	in	in	ADP
fnp-5156	123	22	the	the	DET
fnp-5156	123	23	frequency	frequency	NOUN
fnp-5156	123	24	of	of	ADP
fnp-5156	123	25	distinct	distinct	ADJ
fnp-5156	123	26	amplifications	amplification	NOUN
fnp-5156	123	27	.	.	PUNCT
fnp-5156	124	1	the	the	DET
fnp-5156	124	2	presence	presence	NOUN
fnp-5156	124	3	of	of	ADP
fnp-5156	124	4	these	these	DET
fnp-5156	124	5	gene	gene	NOUN
fnp-5156	124	6	amplifications	amplification	NOUN
fnp-5156	124	7	may	may	AUX
fnp-5156	124	8	be	be	AUX
fnp-5156	124	9	considered	consider	VERB
fnp-5156	124	10	an	an	DET
fnp-5156	124	11	argument	argument	NOUN
fnp-5156	124	12	against	against	ADP
fnp-5156	124	13	the	the	DET
fnp-5156	124	14	diagnosis	diagnosis	NOUN
fnp-5156	124	15	of	of	ADP
fnp-5156	124	16	pxa	pxa	NOUN
fnp-5156	124	17	.	.	PUNCT
fnp-5156	125	1	the	the	DET
fnp-5156	125	2	frequency	frequency	NOUN
fnp-5156	125	3	of	of	ADP
fnp-5156	125	4	homozygous	homozygous	ADJ
fnp-5156	125	5	cdkn2a	cdkn2a	PROPN
fnp-5156	125	6	/	/	SYM
fnp-5156	125	7	b	b	NOUN
fnp-5156	125	8	deletions	deletion	NOUN
fnp-5156	125	9	in	in	ADP
fnp-5156	125	10	932	932	NUM
fnp-5156	125	11	mcpxa	mcpxa	NOUN
fnp-5156	125	12	is	be	AUX
fnp-5156	125	13	close	close	ADJ
fnp-5156	125	14	to	to	PART
fnp-5156	125	15	90	90	NUM
fnp-5156	125	16	%	%	NOUN
fnp-5156	125	17	which	which	PRON
fnp-5156	125	18	exceeds	exceed	VERB
fnp-5156	125	19	the	the	DET
fnp-5156	125	20	incidence	incidence	NOUN
fnp-5156	125	21	of	of	ADP
fnp-5156	125	22	this	this	DET
fnp-5156	125	23	alteration	alteration	NOUN
fnp-5156	125	24	in	in	ADP
fnp-5156	125	25	gbm	gbm	NOUN
fnp-5156	125	26	and	and	CCONJ
fnp-5156	125	27	hgap	hgap	NOUN
fnp-5156	125	28	.	.	PUNCT
fnp-5156	126	1	while	while	SCONJ
fnp-5156	126	2	very	very	ADV
fnp-5156	126	3	characteristic	characteristic	ADJ
fnp-5156	126	4	for	for	ADP
fnp-5156	126	5	pxa	pxa	NOUN
fnp-5156	126	6	,	,	PUNCT
fnp-5156	126	7	the	the	DET
fnp-5156	126	8	high	high	ADJ
fnp-5156	126	9	frequency	frequency	NOUN
fnp-5156	126	10	of	of	ADP
fnp-5156	126	11	homozygous	homozygous	ADJ
fnp-5156	126	12	cdkn2a	cdkn2a	PROPN
fnp-5156	126	13	/	/	SYM
fnp-5156	126	14	b	b	NOUN
fnp-5156	126	15	deletions	deletion	NOUN
fnp-5156	126	16	does	do	AUX
fnp-5156	126	17	not	not	PART
fnp-5156	126	18	distinguish	distinguish	VERB
fnp-5156	126	19	from	from	ADP
fnp-5156	126	20	gbm	gbm	PROPN
fnp-5156	126	21	.	.	PUNCT
fnp-5156	127	1	in	in	ADP
fnp-5156	127	2	conclusion	conclusion	NOUN
fnp-5156	127	3	,	,	PUNCT
fnp-5156	127	4	we	we	PRON
fnp-5156	127	5	are	be	AUX
fnp-5156	127	6	demonstrating	demonstrate	VERB
fnp-5156	127	7	a	a	DET
fnp-5156	127	8	high	high	ADJ
fnp-5156	127	9	homogeneity	homogeneity	NOUN
fnp-5156	127	10	regarding	regard	VERB
fnp-5156	127	11	cnvs	cnvs	NOUN
fnp-5156	127	12	and	and	CCONJ
fnp-5156	127	13	methylation	methylation	NOUN
fnp-5156	127	14	pattern	pattern	NOUN
fnp-5156	127	15	in	in	ADP
fnp-5156	127	16	tumors	tumor	NOUN
fnp-5156	127	17	receiving	receive	VERB
fnp-5156	127	18	the	the	DET
fnp-5156	127	19	methylation	methylation	NOUN
fnp-5156	127	20	-	-	PUNCT
fnp-5156	127	21	based	base	VERB
fnp-5156	127	22	prediction	prediction	NOUN
fnp-5156	127	23	mcpxa	mcpxa	NOUN
fnp-5156	127	24	,	,	PUNCT
fnp-5156	127	25	contrasted	contrast	VERB
fnp-5156	127	26	by	by	ADP
fnp-5156	127	27	a	a	DET
fnp-5156	127	28	high	high	ADJ
fnp-5156	127	29	heterogeneity	heterogeneity	NOUN
fnp-5156	127	30	in	in	ADP
fnp-5156	127	31	histologically	histologically	ADV
fnp-5156	127	32	diagnosed	diagnose	VERB
fnp-5156	127	33	pxa	pxa	NOUN
fnp-5156	127	34	.	.	PUNCT
fnp-5156	128	1	our	our	PRON
fnp-5156	128	2	cnv	cnv	PROPN
fnp-5156	128	3	findings	finding	NOUN
fnp-5156	128	4	in	in	ADP
fnp-5156	128	5	mcpxa	mcpxa	NOUN
fnp-5156	128	6	,	,	PUNCT
fnp-5156	128	7	orthogonal	orthogonal	ADJ
fnp-5156	128	8	to	to	ADP
fnp-5156	128	9	the	the	DET
fnp-5156	128	10	methylation	methylation	NOUN
fnp-5156	128	11	class	class	NOUN
fnp-5156	128	12	predictions	prediction	NOUN
fnp-5156	128	13	,	,	PUNCT
fnp-5156	128	14	provide	provide	VERB
fnp-5156	128	15	independent	independent	ADJ
fnp-5156	128	16	evidence	evidence	NOUN
fnp-5156	128	17	for	for	ADP
fnp-5156	128	18	the	the	DET
fnp-5156	128	19	existence	existence	NOUN
fnp-5156	128	20	of	of	ADP
fnp-5156	128	21	a	a	DET
fnp-5156	128	22	coherent	coherent	ADJ
fnp-5156	128	23	group	group	NOUN
fnp-5156	128	24	of	of	ADP
fnp-5156	128	25	tumors	tumor	NOUN
fnp-5156	128	26	that	that	PRON
fnp-5156	128	27	are	be	AUX
fnp-5156	128	28	unified	unified	ADJ
fnp-5156	128	29	not	not	PART
fnp-5156	128	30	by	by	ADP
fnp-5156	128	31	their	their	PRON
fnp-5156	128	32	histopathology	histopathology	NOUN
fnp-5156	128	33	,	,	PUNCT
fnp-5156	128	34	but	but	CCONJ
fnp-5156	128	35	rather	rather	ADV
fnp-5156	128	36	by	by	ADP
fnp-5156	128	37	their	their	PRON
fnp-5156	128	38	composite	composite	ADJ
fnp-5156	128	39	genomic	genomic	NOUN
fnp-5156	128	40	and	and	CCONJ
fnp-5156	128	41	epigenomic	epigenomic	ADJ
fnp-5156	128	42	signature	signature	NOUN
fnp-5156	128	43	.	.	PUNCT
fnp-5156	129	1	given	give	VERB
fnp-5156	129	2	the	the	DET
fnp-5156	129	3	demonstrated	demonstrate	VERB
fnp-5156	129	4	morphological	morphological	ADJ
fnp-5156	129	5	heterogeneity	heterogeneity	NOUN
fnp-5156	129	6	of	of	ADP
fnp-5156	129	7	mcpxa	mcpxa	NOUN
fnp-5156	129	8	tumors	tumor	NOUN
fnp-5156	129	9	,	,	PUNCT
fnp-5156	129	10	this	this	DET
fnp-5156	129	11	work	work	NOUN
fnp-5156	129	12	contributes	contribute	VERB
fnp-5156	129	13	to	to	ADP
fnp-5156	129	14	providing	provide	VERB
fnp-5156	129	15	an	an	DET
fnp-5156	129	16	alternative	alternative	NOUN
fnp-5156	129	17	for	for	ADP
fnp-5156	129	18	defining	define	VERB
fnp-5156	129	19	pxa	pxa	NOUN
fnp-5156	129	20	on	on	ADP
fnp-5156	129	21	molecular	molecular	ADJ
fnp-5156	129	22	,	,	PUNCT
fnp-5156	129	23	rather	rather	ADV
fnp-5156	129	24	than	than	ADP
fnp-5156	129	25	morphological	morphological	ADJ
fnp-5156	129	26	grounds	ground	NOUN
fnp-5156	129	27	.	.	PUNCT
fnp-5156	130	1	disclosure	disclosure	NOUN
fnp-5156	130	2	m.	m.	PROPN
fnp-5156	130	3	snuderl	snuderl	PROPN
fnp-5156	130	4	,	,	PUNCT
fnp-5156	130	5	d.	d.	PROPN
fnp-5156	130	6	capper	capper	PROPN
fnp-5156	130	7	,	,	PUNCT
fnp-5156	130	8	m.	m.	NOUN
fnp-5156	130	9	sill	sill	NOUN
fnp-5156	130	10	,	,	PUNCT
fnp-5156	130	11	d.t.w	d.t.w	PROPN
fnp-5156	130	12	.	.	PROPN
fnp-5156	130	13	jones	jones	PROPN
fnp-5156	130	14	,	,	PUNCT
fnp-5156	130	15	s.	s.	PROPN
fnp-5156	130	16	pfister	pfister	PROPN
fnp-5156	130	17	,	,	PUNCT
fnp-5156	130	18	d.	d.	PROPN
fnp-5156	130	19	schrimpf	schrimpf	PROPN
fnp-5156	130	20	,	,	PUNCT
fnp-5156	130	21	f.	f.	PROPN
fnp-5156	130	22	sahm	sahm	PROPN
fnp-5156	130	23	and	and	CCONJ
fnp-5156	130	24	a.	a.	PROPN
fnp-5156	130	25	von	von	PROPN
fnp-5156	130	26	deimling	deimling	NOUN
fnp-5156	130	27	are	be	AUX
fnp-5156	130	28	co	co	NOUN
fnp-5156	130	29	-	-	NOUN
fnp-5156	130	30	founders	founder	NOUN
fnp-5156	130	31	and	and	CCONJ
fnp-5156	130	32	shareholders	shareholder	NOUN
fnp-5156	130	33	of	of	ADP
fnp-5156	130	34	heidelberg	heidelberg	PROPN
fnp-5156	130	35	epignostix	epignostix	PROPN
fnp-5156	130	36	gmbh	gmbh	PROPN
fnp-5156	130	37	.	.	PUNCT
fnp-5156	131	1	supplementary	supplementary	ADJ
fnp-5156	131	2	tables	table	NOUN
fnp-5156	131	3	supplementary	supplementary	ADJ
fnp-5156	131	4	table	table	NOUN
fnp-5156	131	5	1	1	NUM
fnp-5156	131	6	(	(	PUNCT
fnp-5156	131	7	download	download	NOUN
fnp-5156	131	8	)	)	PUNCT
fnp-5156	131	9	predictions	prediction	NOUN
fnp-5156	131	10	of	of	ADP
fnp-5156	131	11	heidelberg	heidelberg	NOUN
fnp-5156	131	12	classifier	classifier	NOUN
fnp-5156	131	13	v12_8	v12_8	NOUN
fnp-5156	131	14	in	in	ADP
fnp-5156	131	15	551	551	NUM
fnp-5156	131	16	tumors	tumor	NOUN
fnp-5156	131	17	with	with	ADP
fnp-5156	131	18	the	the	DET
fnp-5156	131	19	diagnosis	diagnosis	NOUN
fnp-5156	131	20	or	or	CCONJ
fnp-5156	131	21	differential	differential	ADJ
fnp-5156	131	22	diagnosis	diagnosis	NOUN
fnp-5156	131	23	of	of	ADP
fnp-5156	131	24	pxa	pxa	NOUN
fnp-5156	131	25	.	.	PUNCT
fnp-5156	132	1	reference	reference	NOUN
fnp-5156	132	2	groups	group	NOUN
fnp-5156	132	3	selected	select	VERB
fnp-5156	132	4	for	for	ADP
fnp-5156	132	5	frequent	frequent	ADJ
fnp-5156	132	6	predictions	prediction	NOUN
fnp-5156	132	7	with	with	ADP
fnp-5156	132	8	a	a	DET
fnp-5156	132	9	calibrated	calibrate	VERB
fnp-5156	132	10	score	score	NOUN
fnp-5156	132	11	>	>	PUNCT
fnp-5156	132	12	=	=	NOUN
fnp-5156	132	13	0.9	0.9	NUM
fnp-5156	132	14	are	be	AUX
fnp-5156	132	15	highlighted	highlight	VERB
fnp-5156	132	16	in	in	ADP
fnp-5156	132	17	green	green	PROPN
fnp-5156	132	18	.	.	PUNCT
fnp-5156	133	1	astrocytoma	astrocytoma	NOUN
fnp-5156	133	2	,	,	PUNCT
fnp-5156	133	3	idh	idh	NOUN
fnp-5156	133	4	-	-	PUNCT
fnp-5156	133	5	mutant	mutant	NOUN
fnp-5156	133	6	and	and	CCONJ
fnp-5156	133	7	diffuse	diffuse	VERB
fnp-5156	133	8	hemispheric	hemispheric	ADJ
fnp-5156	133	9	glioma	glioma	NOUN
fnp-5156	133	10	,	,	PUNCT
fnp-5156	133	11	h3	h3	NOUN
fnp-5156	133	12	g34	g34	NOUN
fnp-5156	133	13	-	-	PUNCT
fnp-5156	133	14	mutant	mutant	NOUN
fnp-5156	133	15	were	be	AUX
fnp-5156	133	16	not	not	PART
fnp-5156	133	17	included	include	VERB
fnp-5156	133	18	for	for	ADP
fnp-5156	133	19	their	their	PRON
fnp-5156	133	20	likely	likely	ADJ
fnp-5156	133	21	detection	detection	NOUN
fnp-5156	133	22	by	by	ADP
fnp-5156	133	23	mutation	mutation	NOUN
fnp-5156	133	24	specific	specific	ADJ
fnp-5156	133	25	antibodies	antibody	NOUN
fnp-5156	133	26	.	.	PUNCT
fnp-5156	134	1	malignant	malignant	ADJ
fnp-5156	134	2	peripheral	peripheral	ADJ
fnp-5156	134	3	nerve	nerve	NOUN
fnp-5156	134	4	sheath	sheath	NOUN
fnp-5156	134	5	tumor	tumor	NOUN
fnp-5156	134	6	(	(	PUNCT
fnp-5156	134	7	spinal	spinal	NOUN
fnp-5156	134	8	or	or	CCONJ
fnp-5156	134	9	atypical	atypical	ADJ
fnp-5156	134	10	type	type	NOUN
fnp-5156	134	11	)	)	PUNCT
fnp-5156	134	12	was	be	AUX
fnp-5156	134	13	excluded	exclude	VERB
fnp-5156	134	14	and	and	CCONJ
fnp-5156	134	15	control	control	NOUN
fnp-5156	134	16	tissue	tissue	NOUN
fnp-5156	134	17	,	,	PUNCT
fnp-5156	134	18	reactive	reactive	ADJ
fnp-5156	134	19	tumor	tumor	NOUN
fnp-5156	134	20	microenvironment	microenvironment	NOUN
fnp-5156	134	21	was	be	AUX
fnp-5156	134	22	also	also	ADV
fnp-5156	134	23	excluded	exclude	VERB
fnp-5156	134	24	.	.	PUNCT
fnp-5156	135	1	supplementary	supplementary	ADJ
fnp-5156	135	2	table	table	NOUN
fnp-5156	135	3	2	2	NUM
fnp-5156	135	4	(	(	PUNCT
fnp-5156	135	5	download	download	NOUN
fnp-5156	135	6	)	)	PUNCT
fnp-5156	135	7	diagnosies	diagnosie	NOUN
fnp-5156	135	8	submitted	submit	VERB
fnp-5156	135	9	to	to	ADP
fnp-5156	135	10	767	767	NUM
fnp-5156	135	11	methylation	methylation	NOUN
fnp-5156	135	12	datasets	dataset	NOUN
fnp-5156	135	13	receiving	receive	VERB
fnp-5156	135	14	a	a	DET
fnp-5156	135	15	heidelberg	heidelberg	NOUN
fnp-5156	135	16	classifier	classifier	NOUN
fnp-5156	135	17	v12_8	v12_8	PROPN
fnp-5156	135	18	prediction	prediction	NOUN
fnp-5156	135	19	of	of	ADP
fnp-5156	135	20	mcpxa	mcpxa	NOUN
fnp-5156	135	21	with	with	ADP
fnp-5156	135	22	a	a	DET
fnp-5156	135	23	calibrated	calibrate	VERB
fnp-5156	135	24	score	score	NOUN
fnp-5156	135	25	>	>	PUNCT
fnp-5156	135	26	=	=	SYM
fnp-5156	135	27	0,9	0,9	NUM
fnp-5156	135	28	.	.	PUNCT
fnp-5156	136	1	supplementary	supplementary	ADJ
fnp-5156	136	2	table	table	NOUN
fnp-5156	136	3	3	3	NUM
fnp-5156	136	4	(	(	PUNCT
fnp-5156	136	5	download	download	NOUN
fnp-5156	136	6	)	)	PUNCT
fnp-5156	136	7	crosstable	crosstable	ADJ
fnp-5156	136	8	chromosomal	chromosomal	ADJ
fnp-5156	136	9	arms	arm	NOUN
fnp-5156	136	10	,	,	PUNCT
fnp-5156	136	11	2418	2418	NUM
fnp-5156	136	12	tumors	tumor	NOUN
fnp-5156	136	13	supplementary	supplementary	ADJ
fnp-5156	136	14	table	table	NOUN
fnp-5156	136	15	4	4	NUM
fnp-5156	136	16	(	(	PUNCT
fnp-5156	136	17	download	download	NOUN
fnp-5156	136	18	)	)	PUNCT
fnp-5156	136	19	crosstable	crosstable	ADJ
fnp-5156	136	20	genes	gene	NOUN
fnp-5156	136	21	,	,	PUNCT
fnp-5156	136	22	selected	select	VERB
fnp-5156	136	23	amplification	amplification	NOUN
fnp-5156	136	24	and	and	CCONJ
fnp-5156	136	25	homozygous	homozygous	ADJ
fnp-5156	136	26	deletions	deletion	NOUN
fnp-5156	136	27	,	,	PUNCT
fnp-5156	136	28	2418	2418	NUM
fnp-5156	136	29	tumors	tumor	NOUN
fnp-5156	136	30	references	reference	VERB
fnp-5156	136	31	1	1	NUM
fnp-5156	136	32	.	.	X
fnp-5156	136	33	kepes	kepes	PROPN
fnp-5156	136	34	jj	jj	PROPN
fnp-5156	136	35	,	,	PUNCT
fnp-5156	136	36	rubinstein	rubinstein	PROPN
fnp-5156	136	37	lj	lj	PROPN
fnp-5156	136	38	,	,	PUNCT
fnp-5156	136	39	eng	eng	PROPN
fnp-5156	136	40	lf	lf	PROPN
fnp-5156	136	41	.	.	PROPN
fnp-5156	136	42	1979	1979	NUM
fnp-5156	136	43	.	.	PUNCT
fnp-5156	137	1	pleomorphic	pleomorphic	ADJ
fnp-5156	137	2	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	137	3	:	:	PUNCT
fnp-5156	137	4	a	a	DET
fnp-5156	137	5	distinctive	distinctive	ADJ
fnp-5156	137	6	meningocerebral	meningocerebral	ADJ
fnp-5156	137	7	glioma	glioma	NOUN
fnp-5156	137	8	of	of	ADP
fnp-5156	137	9	young	young	ADJ
fnp-5156	137	10	subjects	subject	NOUN
fnp-5156	137	11	with	with	ADP
fnp-5156	137	12	relatively	relatively	ADV
fnp-5156	137	13	favorable	favorable	ADJ
fnp-5156	137	14	prognosis	prognosis	NOUN
fnp-5156	137	15	.	.	PUNCT
fnp-5156	138	1	a	a	DET
fnp-5156	138	2	study	study	NOUN
fnp-5156	138	3	of	of	ADP
fnp-5156	138	4	12	12	NUM
fnp-5156	138	5	cases	case	NOUN
fnp-5156	138	6	.	.	PUNCT
fnp-5156	139	1	cancer	cancer	NOUN
fnp-5156	139	2	44:1839	44:1839	PROPN
fnp-5156	139	3	-	-	SYM
fnp-5156	139	4	52	52	NUM
fnp-5156	139	5	.	.	PUNCT
fnp-5156	139	6	doi	doi	NOUN
fnp-5156	139	7	:	:	PUNCT
fnp-5156	139	8	https://doi.org/10.1002/1097-0142(197911)44:5<1839::aid-cncr2820440543>3.0.co;2-0	https://doi.org/10.1002/1097-0142(197911)44:5<1839::aid-cncr2820440543>3.0.co;2-0	PROPN
fnp-5156	139	9	2	2	X
fnp-5156	139	10	.	.	PUNCT
fnp-5156	140	1	giannini	giannini	PROPN
fnp-5156	140	2	c	c	PROPN
fnp-5156	140	3	,	,	PUNCT
fnp-5156	140	4	scheithauer	scheithauer	NOUN
fnp-5156	140	5	bw	bw	NOUN
fnp-5156	140	6	,	,	PUNCT
fnp-5156	140	7	burger	burger	NOUN
fnp-5156	140	8	pc	pc	NOUN
fnp-5156	140	9	,	,	PUNCT
fnp-5156	140	10	brat	brat	NOUN
fnp-5156	140	11	dj	dj	NOUN
fnp-5156	140	12	,	,	PUNCT
fnp-5156	140	13	wollan	wollan	NOUN
fnp-5156	140	14	pc	pc	NOUN
fnp-5156	140	15	,	,	PUNCT
fnp-5156	140	16	et	et	PROPN
fnp-5156	140	17	al	al	PROPN
fnp-5156	140	18	.	.	PROPN
fnp-5156	140	19	1999	1999	NUM
fnp-5156	140	20	.	.	PUNCT
fnp-5156	141	1	pleomorphic	pleomorphic	ADJ
fnp-5156	141	2	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	141	3	:	:	PUNCT
fnp-5156	141	4	what	what	PRON
fnp-5156	141	5	do	do	AUX
fnp-5156	141	6	we	we	PRON
fnp-5156	141	7	really	really	ADV
fnp-5156	141	8	know	know	VERB
fnp-5156	141	9	about	about	ADP
fnp-5156	141	10	it	it	PRON
fnp-5156	141	11	?	?	PUNCT
fnp-5156	142	1	cancer	cancer	NOUN
fnp-5156	142	2	85:2033	85:2033	NUM
fnp-5156	142	3	-	-	SYM
fnp-5156	142	4	45	45	NUM
fnp-5156	142	5	.	.	PUNCT
fnp-5156	143	1	doi	doi	NOUN
fnp-5156	143	2	:	:	PUNCT
fnp-5156	143	3	https://doi.org/10.1002/(sici)1097-0142(19990501)85:9<2033::aid-cncr22>3.0.co;2-z	https://doi.org/10.1002/(sici)1097-0142(19990501)85:9<2033::aid-cncr22>3.0.co;2-z	PROPN
fnp-5156	143	4	3	3	NUM
fnp-5156	143	5	.	.	PUNCT
fnp-5156	144	1	who	who	PRON
fnp-5156	144	2	-	-	PUNCT
fnp-5156	144	3	classification	classification	NOUN
fnp-5156	144	4	-	-	PUNCT
fnp-5156	144	5	of	of	ADP
fnp-5156	144	6	-	-	PUNCT
fnp-5156	144	7	tumours	tumours	ADJ
fnp-5156	144	8	-	-	PUNCT
fnp-5156	144	9	editorial	editorial	ADJ
fnp-5156	144	10	-	-	PUNCT
fnp-5156	144	11	board	board	NOUN
fnp-5156	144	12	,	,	PUNCT
fnp-5156	144	13	ed	ed	NOUN
fnp-5156	144	14	.	.	PROPN
fnp-5156	144	15	2021	2021	NUM
fnp-5156	144	16	.	.	PUNCT
fnp-5156	145	1	central	central	ADJ
fnp-5156	145	2	nervous	nervous	ADJ
fnp-5156	145	3	system	system	NOUN
fnp-5156	145	4	tumours	tumour	NOUN
fnp-5156	145	5	,	,	PUNCT
fnp-5156	145	6	vols	vol	NOUN
fnp-5156	145	7	.	.	PUNCT
fnp-5156	146	1	6	6	X
fnp-5156	146	2	.	.	X
fnp-5156	146	3	lyon	lyon	PROPN
fnp-5156	146	4	,	,	PUNCT
fnp-5156	146	5	france	france	PROPN
fnp-5156	146	6	.	.	PUNCT
fnp-5156	147	1	5	5	NUM
fnp-5156	147	2	ed	ed	NOUN
fnp-5156	147	3	.	.	NOUN
fnp-5156	148	1	4	4	NUM
fnp-5156	148	2	.	.	X
fnp-5156	148	3	ebrahimi	ebrahimi	PROPN
fnp-5156	148	4	a	a	X
fnp-5156	148	5	,	,	PUNCT
fnp-5156	148	6	korshunov	korshunov	NOUN
fnp-5156	148	7	a	a	PRON
fnp-5156	148	8	,	,	PUNCT
fnp-5156	148	9	reifenberger	reifenberger	NOUN
fnp-5156	148	10	g	g	NOUN
fnp-5156	148	11	,	,	PUNCT
fnp-5156	148	12	capper	capper	NOUN
fnp-5156	148	13	d	d	PROPN
fnp-5156	148	14	,	,	PUNCT
fnp-5156	148	15	felsberg	felsberg	PROPN
fnp-5156	148	16	j	j	PROPN
fnp-5156	148	17	,	,	PUNCT
fnp-5156	148	18	et	et	PROPN
fnp-5156	148	19	al	al	PROPN
fnp-5156	148	20	.	.	PROPN
fnp-5156	148	21	2022	2022	NUM
fnp-5156	148	22	.	.	PUNCT
fnp-5156	149	1	pleomorphic	pleomorphic	ADJ
fnp-5156	149	2	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	149	3	is	be	AUX
fnp-5156	149	4	a	a	DET
fnp-5156	149	5	heterogeneous	heterogeneous	ADJ
fnp-5156	149	6	entity	entity	NOUN
fnp-5156	149	7	with	with	ADP
fnp-5156	149	8	ptert	ptert	ADJ
fnp-5156	149	9	mutations	mutation	NOUN
fnp-5156	149	10	prognosticating	prognosticate	VERB
fnp-5156	149	11	shorter	short	ADJ
fnp-5156	149	12	survival	survival	NOUN
fnp-5156	149	13	.	.	PUNCT
fnp-5156	150	1	acta	acta	PROPN
fnp-5156	150	2	neuropathol	neuropathol	PROPN
fnp-5156	150	3	commun	commun	PROPN
fnp-5156	150	4	10:5	10:5	X
fnp-5156	150	5	.	.	PUNCT
fnp-5156	151	1	doi	doi	PROPN
fnp-5156	151	2	:	:	PUNCT
fnp-5156	151	3	https://doi.org/10.1186/s40478-021-01308-1	https://doi.org/10.1186/s40478-021-01308-1	PROPN
fnp-5156	151	4	5	5	NUM
fnp-5156	151	5	.	.	PUNCT
fnp-5156	151	6	phillips	phillips	PROPN
fnp-5156	151	7	jj	jj	PROPN
fnp-5156	151	8	,	,	PUNCT
fnp-5156	151	9	gong	gong	PROPN
fnp-5156	151	10	h	h	PROPN
fnp-5156	151	11	,	,	PUNCT
fnp-5156	151	12	chen	chen	PROPN
fnp-5156	151	13	k	k	PROPN
fnp-5156	151	14	,	,	PUNCT
fnp-5156	151	15	joseph	joseph	PROPN
fnp-5156	151	16	nm	nm	PROPN
fnp-5156	151	17	,	,	PUNCT
fnp-5156	151	18	van	van	PROPN
fnp-5156	151	19	ziffle	ziffle	PROPN
fnp-5156	151	20	j	j	PROPN
fnp-5156	151	21	,	,	PUNCT
fnp-5156	151	22	et	et	PROPN
fnp-5156	151	23	al	al	PROPN
fnp-5156	151	24	.	.	PROPN
fnp-5156	151	25	2019	2019	NUM
fnp-5156	151	26	.	.	PUNCT
fnp-5156	152	1	the	the	DET
fnp-5156	152	2	genetic	genetic	ADJ
fnp-5156	152	3	landscape	landscape	NOUN
fnp-5156	152	4	of	of	ADP
fnp-5156	152	5	anaplastic	anaplastic	ADJ
fnp-5156	152	6	pleomorphic	pleomorphic	ADJ
fnp-5156	152	7	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	152	8	.	.	PUNCT
fnp-5156	153	1	brain	brain	NOUN
fnp-5156	153	2	pathol	pathol	NOUN
fnp-5156	153	3	29:85	29:85	NUM
fnp-5156	153	4	-	-	SYM
fnp-5156	153	5	96	96	NUM
fnp-5156	153	6	.	.	PUNCT
fnp-5156	154	1	doi	doi	NOUN
fnp-5156	154	2	:	:	PUNCT
fnp-5156	154	3	https://doi.org/10.1111/bpa.12639	https://doi.org/10.1111/bpa.12639	PROPN
fnp-5156	154	4	6	6	NUM
fnp-5156	154	5	.	.	PUNCT
fnp-5156	154	6	nakamura	nakamura	PROPN
fnp-5156	154	7	t	t	PROPN
fnp-5156	154	8	,	,	PUNCT
fnp-5156	154	9	fukuoka	fukuoka	PROPN
fnp-5156	154	10	k	k	PROPN
fnp-5156	154	11	,	,	PUNCT
fnp-5156	154	12	nakano	nakano	PROPN
fnp-5156	154	13	y	y	PROPN
fnp-5156	154	14	,	,	PUNCT
fnp-5156	154	15	yamasaki	yamasaki	PROPN
fnp-5156	154	16	k	k	PROPN
fnp-5156	154	17	,	,	PUNCT
fnp-5156	154	18	matsushita	matsushita	PROPN
fnp-5156	154	19	y	y	PROPN
fnp-5156	154	20	,	,	PUNCT
fnp-5156	154	21	et	et	PROPN
fnp-5156	154	22	al	al	PROPN
fnp-5156	154	23	.	.	PROPN
fnp-5156	154	24	2019	2019	NUM
fnp-5156	154	25	.	.	PUNCT
fnp-5156	155	1	genome	genome	NOUN
fnp-5156	155	2	-	-	PUNCT
fnp-5156	155	3	wide	wide	ADJ
fnp-5156	155	4	dna	dna	PROPN
fnp-5156	155	5	methylation	methylation	NOUN
fnp-5156	155	6	profiling	profiling	NOUN
fnp-5156	155	7	shows	show	VERB
fnp-5156	155	8	molecular	molecular	ADJ
fnp-5156	155	9	heterogeneity	heterogeneity	NOUN
fnp-5156	155	10	of	of	ADP
fnp-5156	155	11	anaplastic	anaplastic	ADJ
fnp-5156	155	12	pleomorphic	pleomorphic	ADJ
fnp-5156	155	13	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	155	14	.	.	PUNCT
fnp-5156	156	1	cancer	cancer	NOUN
fnp-5156	156	2	sci	sci	PROPN
fnp-5156	156	3	110:828	110:828	PROPN
fnp-5156	156	4	-	-	PUNCT
fnp-5156	156	5	32	32	NUM
fnp-5156	156	6	.	.	PUNCT
fnp-5156	157	1	doi	doi	NOUN
fnp-5156	157	2	:	:	PUNCT
fnp-5156	158	1	https://doi.org/10.1111/cas.13903	https://doi.org/10.1111/cas.13903	PROPN
fnp-5156	158	2	7	7	X
fnp-5156	158	3	.	.	X
fnp-5156	158	4	vaubel	vaubel	PROPN
fnp-5156	158	5	ra	ra	PROPN
fnp-5156	158	6	,	,	PUNCT
fnp-5156	158	7	caron	caron	PROPN
fnp-5156	158	8	aa	aa	PROPN
fnp-5156	158	9	,	,	PUNCT
fnp-5156	158	10	yamada	yamada	PROPN
fnp-5156	158	11	s	s	PROPN
fnp-5156	158	12	,	,	PUNCT
fnp-5156	158	13	decker	decker	PROPN
fnp-5156	158	14	pa	pa	PROPN
fnp-5156	158	15	,	,	PUNCT
fnp-5156	158	16	eckel	eckel	NOUN
fnp-5156	158	17	passow	passow	PROPN
fnp-5156	158	18	je	je	PROPN
fnp-5156	158	19	,	,	PUNCT
fnp-5156	158	20	et	et	PROPN
fnp-5156	158	21	al	al	PROPN
fnp-5156	158	22	.	.	PROPN
fnp-5156	158	23	2018	2018	NUM
fnp-5156	158	24	.	.	PUNCT
fnp-5156	159	1	recurrent	recurrent	ADJ
fnp-5156	159	2	copy	copy	NOUN
fnp-5156	159	3	number	number	NOUN
fnp-5156	159	4	alterations	alteration	NOUN
fnp-5156	159	5	in	in	ADP
fnp-5156	159	6	low	low	ADJ
fnp-5156	159	7	-	-	PUNCT
fnp-5156	159	8	grade	grade	NOUN
fnp-5156	159	9	and	and	CCONJ
fnp-5156	159	10	anaplastic	anaplastic	ADJ
fnp-5156	159	11	pleomorphic	pleomorphic	ADJ
fnp-5156	159	12	xanthoastrocytoma	xanthoastrocytoma	NOUN
fnp-5156	159	13	with	with	ADP
fnp-5156	159	14	and	and	CCONJ
fnp-5156	159	15	without	without	ADP
fnp-5156	159	16	braf	braf	NOUN
fnp-5156	159	17	v600e	v600e	NOUN
fnp-5156	159	18	mutation	mutation	NOUN
fnp-5156	159	19	.	.	PUNCT
fnp-5156	160	1	brain	brain	NOUN
fnp-5156	160	2	pathol	pathol	NOUN
fnp-5156	160	3	28:172	28:172	PROPN
fnp-5156	160	4	-	-	SYM
fnp-5156	160	5	82	82	NUM
fnp-5156	160	6	.	.	PUNCT
fnp-5156	161	1	doi	doi	NOUN
fnp-5156	161	2	:	:	PUNCT
fnp-5156	161	3	https://doi.org/10.1111/bpa.12495	https://doi.org/10.1111/bpa.12495	ADJ
fnp-5156	161	4	8	8	NUM
fnp-5156	161	5	.	.	PUNCT
fnp-5156	162	1	capper	capper	PROPN
fnp-5156	162	2	d	d	PROPN
fnp-5156	162	3	,	,	PUNCT
fnp-5156	162	4	jones	jones	PROPN
fnp-5156	162	5	dtw	dtw	PROPN
fnp-5156	162	6	,	,	PUNCT
fnp-5156	162	7	sill	sill	NOUN
fnp-5156	162	8	m	m	PROPN
fnp-5156	162	9	,	,	PUNCT
fnp-5156	162	10	hovestadt	hovestadt	ADJ
fnp-5156	162	11	v	v	NOUN
fnp-5156	162	12	,	,	PUNCT
fnp-5156	162	13	schrimpf	schrimpf	NOUN
fnp-5156	162	14	d	d	NOUN
fnp-5156	162	15	,	,	PUNCT
fnp-5156	162	16	et	et	PROPN
fnp-5156	162	17	al	al	PROPN
fnp-5156	162	18	.	.	PROPN
fnp-5156	162	19	2018	2018	NUM
fnp-5156	162	20	.	.	PUNCT
fnp-5156	163	1	dna	dna	PROPN
fnp-5156	163	2	methylation	methylation	NOUN
fnp-5156	163	3	-	-	PUNCT
fnp-5156	163	4	based	base	VERB
fnp-5156	163	5	classification	classification	NOUN
fnp-5156	163	6	of	of	ADP
fnp-5156	163	7	central	central	ADJ
fnp-5156	163	8	nervous	nervous	ADJ
fnp-5156	163	9	system	system	NOUN
fnp-5156	163	10	tumours	tumour	VERB
fnp-5156	163	11	.	.	PUNCT
fnp-5156	164	1	nature	nature	NOUN
fnp-5156	164	2	555:469	555:469	PROPN
fnp-5156	164	3	-	-	SYM
fnp-5156	164	4	74	74	NUM
fnp-5156	164	5	.	.	PUNCT
fnp-5156	165	1	doi	doi	NOUN
fnp-5156	165	2	:	:	PUNCT
fnp-5156	165	3	https://doi.org/10.1038/nature26000	https://doi.org/10.1038/nature26000	PROPN
fnp-5156	165	4	9	9	NUM
fnp-5156	165	5	.	.	PUNCT
fnp-5156	166	1	stichel	stichel	PROPN
fnp-5156	167	1	d	d	PROPN
fnp-5156	167	2	,	,	PUNCT
fnp-5156	167	3	ebrahimi	ebrahimi	PROPN
fnp-5156	167	4	a	a	X
fnp-5156	167	5	,	,	PUNCT
fnp-5156	167	6	reuss	reuss	PROPN
fnp-5156	167	7	d	d	PROPN
fnp-5156	167	8	,	,	PUNCT
fnp-5156	167	9	schrimpf	schrimpf	NOUN
fnp-5156	167	10	d	d	PROPN
fnp-5156	167	11	,	,	PUNCT
fnp-5156	167	12	ono	ono	PROPN
fnp-5156	167	13	t	t	PROPN
fnp-5156	167	14	,	,	PUNCT
fnp-5156	167	15	et	et	PROPN
fnp-5156	167	16	al	al	PROPN
fnp-5156	167	17	.	.	PROPN
fnp-5156	167	18	2018	2018	NUM
fnp-5156	167	19	.	.	PUNCT
fnp-5156	168	1	distribution	distribution	NOUN
fnp-5156	168	2	of	of	ADP
fnp-5156	168	3	egfr	egfr	ADJ
fnp-5156	168	4	amplification	amplification	NOUN
fnp-5156	168	5	,	,	PUNCT
fnp-5156	168	6	combined	combined	ADJ
fnp-5156	168	7	chromosome	chromosome	NOUN
fnp-5156	168	8	7	7	NUM
fnp-5156	168	9	gain	gain	NOUN
fnp-5156	168	10	and	and	CCONJ
fnp-5156	168	11	chromosome	chromosome	VERB
fnp-5156	168	12	10	10	NUM
fnp-5156	168	13	loss	loss	NOUN
fnp-5156	168	14	,	,	PUNCT
fnp-5156	168	15	and	and	CCONJ
fnp-5156	168	16	tert	tert	NOUN
fnp-5156	168	17	promoter	promoter	NOUN
fnp-5156	168	18	mutation	mutation	NOUN
fnp-5156	168	19	in	in	ADP
fnp-5156	168	20	brain	brain	NOUN
fnp-5156	168	21	tumors	tumor	NOUN
fnp-5156	168	22	and	and	CCONJ
fnp-5156	168	23	their	their	PRON
fnp-5156	168	24	potential	potential	NOUN
fnp-5156	168	25	for	for	ADP
fnp-5156	168	26	the	the	DET
fnp-5156	168	27	reclassification	reclassification	NOUN
fnp-5156	168	28	of	of	ADP
fnp-5156	168	29	idhwt	idhwt	PROPN
fnp-5156	168	30	astrocytoma	astrocytoma	PROPN
fnp-5156	168	31	to	to	ADP
fnp-5156	168	32	glioblastoma	glioblastoma	NOUN
fnp-5156	168	33	.	.	PUNCT
fnp-5156	169	1	acta	acta	PROPN
fnp-5156	169	2	neuropathol	neuropathol	PROPN
fnp-5156	169	3	136:793	136:793	NUM
fnp-5156	169	4	-	-	PUNCT
fnp-5156	169	5	803	803	NUM
fnp-5156	169	6	.	.	PUNCT
fnp-5156	170	1	doi	doi	NOUN
fnp-5156	170	2	:	:	PUNCT
fnp-5156	170	3	https://doi.org/10.1007/s00401-018-1905-0	https://doi.org/10.1007/s00401-018-1905-0	NUM
fnp-5156	170	4	10	10	NUM
fnp-5156	170	5	.	.	PUNCT
fnp-5156	171	1	weber	weber	PROPN
fnp-5156	171	2	rg	rg	PROPN
fnp-5156	171	3	,	,	PUNCT
fnp-5156	171	4	hoischen	hoischen	X
fnp-5156	171	5	a	a	X
fnp-5156	171	6	,	,	PUNCT
fnp-5156	171	7	ehrler	ehrler	NOUN
fnp-5156	171	8	m	m	PROPN
fnp-5156	171	9	,	,	PUNCT
fnp-5156	171	10	zipper	zipper	NOUN
fnp-5156	171	11	p	p	NOUN
fnp-5156	171	12	,	,	PUNCT
fnp-5156	171	13	kaulich	kaulich	PROPN
fnp-5156	171	14	k	k	PROPN
fnp-5156	171	15	,	,	PUNCT
fnp-5156	171	16	et	et	PROPN
fnp-5156	171	17	al	al	PROPN
fnp-5156	171	18	.	.	PROPN
fnp-5156	171	19	2007	2007	NUM
fnp-5156	171	20	.	.	PUNCT
fnp-5156	172	1	frequent	frequent	ADJ
fnp-5156	172	2	loss	loss	NOUN
fnp-5156	172	3	of	of	ADP
fnp-5156	172	4	chromosome	chromosome	NOUN
fnp-5156	172	5	9	9	NUM
fnp-5156	172	6	,	,	PUNCT
fnp-5156	172	7	homozygous	homozygous	ADJ
fnp-5156	172	8	cdkn2a	cdkn2a	PROPN
fnp-5156	172	9	/	/	SYM
fnp-5156	172	10	p14(arf)/cdkn2b	p14(arf)/cdkn2b	NOUN
fnp-5156	172	11	deletion	deletion	NOUN
fnp-5156	172	12	and	and	CCONJ
fnp-5156	172	13	low	low	ADJ
fnp-5156	172	14	tsc1	tsc1	PROPN
fnp-5156	172	15	mrna	mrna	PROPN
fnp-5156	172	16	expression	expression	NOUN
fnp-5156	172	17	in	in	ADP
fnp-5156	172	18	pleomorphic	pleomorphic	ADJ
fnp-5156	172	19	xanthoastrocytomas	xanthoastrocytoma	NOUN
fnp-5156	172	20	.	.	PUNCT
fnp-5156	173	1	oncogene	oncogene	NOUN
fnp-5156	173	2	26:1088	26:1088	PROPN
fnp-5156	173	3	-	-	SYM
fnp-5156	173	4	97	97	NUM
fnp-5156	173	5	.	.	PUNCT
fnp-5156	174	1	doi	doi	NOUN
fnp-5156	174	2	:	:	PUNCT
fnp-5156	174	3	https://doi.org/10.1038/sj.onc.1209851	https://doi.org/10.1038/sj.onc.1209851	NOUN
fnp-5156	174	4	copyright	copyright	NOUN
fnp-5156	174	5	:	:	PUNCT
fnp-5156	174	6	©	©	PROPN
fnp-5156	174	7	2023	2023	NUM
fnp-5156	174	8	the	the	DET
fnp-5156	174	9	author(s	author(s	NOUN
fnp-5156	174	10	)	)	PUNCT
fnp-5156	174	11	.	.	PUNCT
fnp-5156	175	1	this	this	PRON
fnp-5156	175	2	is	be	AUX
fnp-5156	175	3	an	an	DET
fnp-5156	175	4	open	open	ADJ
fnp-5156	175	5	access	access	NOUN
fnp-5156	175	6	article	article	NOUN
fnp-5156	175	7	distributed	distribute	VERB
fnp-5156	175	8	under	under	ADP
fnp-5156	175	9	the	the	DET
fnp-5156	175	10	terms	term	NOUN
fnp-5156	175	11	of	of	ADP
fnp-5156	175	12	the	the	DET
fnp-5156	175	13	creative	creative	ADJ
fnp-5156	175	14	commons	common	NOUN
fnp-5156	175	15	attribution	attribution	NOUN
fnp-5156	175	16	4.0	4.0	NUM
fnp-5156	175	17	international	international	ADJ
fnp-5156	175	18	license	license	NOUN
fnp-5156	175	19	(	(	PUNCT
fnp-5156	175	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5156	175	21	)	)	PUNCT
fnp-5156	175	22	,	,	PUNCT
fnp-5156	175	23	which	which	PRON
fnp-5156	175	24	permits	permit	VERB
fnp-5156	175	25	unrestricted	unrestricted	ADJ
fnp-5156	175	26	use	use	NOUN
fnp-5156	175	27	,	,	PUNCT
fnp-5156	175	28	distribution	distribution	NOUN
fnp-5156	175	29	,	,	PUNCT
fnp-5156	175	30	and	and	CCONJ
fnp-5156	175	31	reproduction	reproduction	NOUN
fnp-5156	175	32	in	in	ADP
fnp-5156	175	33	any	any	DET
fnp-5156	175	34	medium	medium	NOUN
fnp-5156	175	35	,	,	PUNCT
fnp-5156	175	36	provided	provide	VERB
fnp-5156	175	37	the	the	DET
fnp-5156	175	38	original	original	ADJ
fnp-5156	175	39	author	author	NOUN
fnp-5156	175	40	and	and	CCONJ
fnp-5156	175	41	source	source	NOUN
fnp-5156	175	42	are	be	AUX
fnp-5156	175	43	credited	credit	VERB
fnp-5156	175	44	,	,	PUNCT
fnp-5156	175	45	a	a	DET
fnp-5156	175	46	link	link	NOUN
fnp-5156	175	47	to	to	ADP
fnp-5156	175	48	the	the	DET
fnp-5156	175	49	creative	creative	ADJ
fnp-5156	175	50	commons	common	NOUN
fnp-5156	175	51	license	license	NOUN
fnp-5156	175	52	is	be	AUX
fnp-5156	175	53	provided	provide	VERB
fnp-5156	175	54	,	,	PUNCT
fnp-5156	175	55	and	and	CCONJ
fnp-5156	175	56	any	any	DET
fnp-5156	175	57	changes	change	NOUN
fnp-5156	175	58	are	be	AUX
fnp-5156	175	59	indicated	indicate	VERB
fnp-5156	175	60	.	.	PUNCT
fnp-5156	176	1	the	the	DET
fnp-5156	176	2	creative	creative	ADJ
fnp-5156	176	3	commons	common	NOUN
fnp-5156	176	4	public	public	ADJ
fnp-5156	176	5	domain	domain	NOUN
fnp-5156	176	6	dedication	dedication	NOUN
fnp-5156	176	7	waiver	waiver	NOUN
fnp-5156	176	8	(	(	PUNCT
fnp-5156	176	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-5156	176	10	)	)	PUNCT
fnp-5156	176	11	applies	apply	VERB
fnp-5156	176	12	to	to	ADP
fnp-5156	176	13	the	the	DET
fnp-5156	176	14	data	datum	NOUN
fnp-5156	176	15	made	make	VERB
fnp-5156	176	16	available	available	ADJ
fnp-5156	176	17	in	in	ADP
fnp-5156	176	18	this	this	DET
fnp-5156	176	19	article	article	NOUN
fnp-5156	176	20	,	,	PUNCT
fnp-5156	176	21	unless	unless	SCONJ
fnp-5156	176	22	otherwise	otherwise	ADV
fnp-5156	176	23	stated	state	VERB
fnp-5156	176	24	.	.	PUNCT