id	sid	tid	token	lemma	pos
fnp-5721	1	1	striking	strike	VERB
fnp-5721	1	2	intraneuronal	intraneuronal	ADJ
fnp-5721	1	3	neurofilament	neurofilament	ADJ
fnp-5721	1	4	inclusions	inclusion	NOUN
fnp-5721	1	5	restricted	restrict	VERB
fnp-5721	1	6	to	to	ADP
fnp-5721	1	7	the	the	DET
fnp-5721	1	8	locus	locus	ADJ
fnp-5721	1	9	coeruleus	coeruleus	NOUN
fnp-5721	1	10	in	in	ADP
fnp-5721	1	11	a	a	DET
fnp-5721	1	12	patient	patient	NOUN
fnp-5721	1	13	with	with	ADP
fnp-5721	1	14	creutzfeldt	creutzfeldt	ADJ
fnp-5721	1	15	-	-	ADJ
fnp-5721	1	16	jakob	jakob	ADJ
fnp-5721	1	17	disease	disease	NOUN
fnp-5721	1	18	feel	feel	VERB
fnp-5721	1	19	free	free	ADJ
fnp-5721	1	20	to	to	PART
fnp-5721	1	21	add	add	VERB
fnp-5721	1	22	comments	comment	NOUN
fnp-5721	1	23	by	by	ADP
fnp-5721	1	24	clicking	click	VERB
fnp-5721	1	25	these	these	DET
fnp-5721	1	26	icons	icon	NOUN
fnp-5721	1	27	on	on	ADP
fnp-5721	1	28	the	the	DET
fnp-5721	1	29	sidebar	sidebar	NOUN
fnp-5721	1	30	free	free	ADJ
fnp-5721	1	31	neuropathology	neuropathology	NOUN
fnp-5721	1	32	5:22	5:22	NUM
fnp-5721	1	33	(	(	PUNCT
fnp-5721	1	34	2024	2024	NUM
fnp-5721	1	35	)	)	PUNCT
fnp-5721	1	36	letter	letter	NOUN
fnp-5721	1	37	striking	strike	VERB
fnp-5721	1	38	intraneuronal	intraneuronal	ADJ
fnp-5721	1	39	neurofilament	neurofilament	ADJ
fnp-5721	1	40	inclusions	inclusion	NOUN
fnp-5721	1	41	restricted	restrict	VERB
fnp-5721	1	42	to	to	ADP
fnp-5721	1	43	the	the	DET
fnp-5721	1	44	locus	locus	ADJ
fnp-5721	1	45	coeruleus	coeruleus	NOUN
fnp-5721	1	46	in	in	ADP
fnp-5721	1	47	a	a	DET
fnp-5721	1	48	patient	patient	NOUN
fnp-5721	1	49	with	with	ADP
fnp-5721	1	50	creutzfeldt	creutzfeldt	ADJ
fnp-5721	1	51	-	-	ADJ
fnp-5721	1	52	jakob	jakob	ADJ
fnp-5721	1	53	disease	disease	NOUN
fnp-5721	1	54	felix	felix	PROPN
fnp-5721	1	55	leitner1,2	leitner1,2	PROPN
fnp-5721	1	56	,	,	PUNCT
fnp-5721	1	57	sigrid	sigrid	VERB
fnp-5721	1	58	klotz1,2	klotz1,2	PROPN
fnp-5721	1	59	,	,	PUNCT
fnp-5721	1	60	karoline	karoline	PROPN
fnp-5721	1	61	ornig3	ornig3	PROPN
fnp-5721	1	62	,	,	PUNCT
fnp-5721	1	63	serge	serge	NOUN
fnp-5721	1	64	weis3	weis3	PROPN
fnp-5721	1	65	,	,	PUNCT
fnp-5721	1	66	ellen	ellen	PROPN
fnp-5721	1	67	gelpi1,2	gelpi1,2	PROPN
fnp-5721	1	68	division	division	NOUN
fnp-5721	1	69	of	of	ADP
fnp-5721	1	70	neuropathology	neuropathology	NOUN
fnp-5721	1	71	and	and	CCONJ
fnp-5721	1	72	neurochemistry	neurochemistry	NOUN
fnp-5721	1	73	,	,	PUNCT
fnp-5721	1	74	department	department	NOUN
fnp-5721	1	75	of	of	ADP
fnp-5721	1	76	neurology	neurology	NOUN
fnp-5721	1	77	,	,	PUNCT
fnp-5721	1	78	medical	medical	ADJ
fnp-5721	1	79	university	university	PROPN
fnp-5721	1	80	of	of	ADP
fnp-5721	1	81	vienna	vienna	PROPN
fnp-5721	1	82	,	,	PUNCT
fnp-5721	1	83	1090	1090	NUM
fnp-5721	1	84	vienna	vienna	NOUN
fnp-5721	1	85	,	,	PUNCT
fnp-5721	1	86	austria	austria	PROPN
fnp-5721	1	87	austrian	austrian	ADJ
fnp-5721	1	88	reference	reference	NOUN
fnp-5721	1	89	center	center	NOUN
fnp-5721	1	90	for	for	ADP
fnp-5721	1	91	human	human	ADJ
fnp-5721	1	92	prion	prion	NOUN
fnp-5721	1	93	diseases	disease	NOUN
fnp-5721	1	94	(	(	PUNCT
fnp-5721	1	95	oerpe	oerpe	NOUN
fnp-5721	1	96	)	)	PUNCT
fnp-5721	1	97	division	division	NOUN
fnp-5721	1	98	of	of	ADP
fnp-5721	1	99	neuropathology	neuropathology	NOUN
fnp-5721	1	100	,	,	PUNCT
fnp-5721	1	101	department	department	NOUN
fnp-5721	1	102	of	of	ADP
fnp-5721	1	103	pathology	pathology	NOUN
fnp-5721	1	104	and	and	CCONJ
fnp-5721	1	105	molecular	molecular	ADJ
fnp-5721	1	106	pathology	pathology	NOUN
fnp-5721	1	107	,	,	PUNCT
fnp-5721	1	108	neuromed	neuromed	PROPN
fnp-5721	1	109	campus	campus	PROPN
fnp-5721	1	110	,	,	PUNCT
fnp-5721	1	111	kepler	kepler	PROPN
fnp-5721	1	112	university	university	PROPN
fnp-5721	1	113	hospital	hospital	NOUN
fnp-5721	1	114	,	,	PUNCT
fnp-5721	1	115	linz	linz	PROPN
fnp-5721	1	116	,	,	PUNCT
fnp-5721	1	117	austria	austria	PROPN
fnp-5721	1	118	corresponding	correspond	VERB
fnp-5721	1	119	author	author	NOUN
fnp-5721	1	120	:	:	PUNCT
fnp-5721	1	121	ellen	ellen	PROPN
fnp-5721	1	122	gelpi	gelpi	PROPN
fnp-5721	1	123	·	·	PUNCT
fnp-5721	1	124	division	division	NOUN
fnp-5721	1	125	of	of	ADP
fnp-5721	1	126	neuropathology	neuropathology	NOUN
fnp-5721	1	127	and	and	CCONJ
fnp-5721	1	128	neurochemistry	neurochemistry	PROPN
fnp-5721	1	129	·	·	PUNCT
fnp-5721	1	130	department	department	NOUN
fnp-5721	1	131	of	of	ADP
fnp-5721	1	132	neurology	neurology	NOUN
fnp-5721	1	133	·	·	PUNCT
fnp-5721	1	134	medical	medical	ADJ
fnp-5721	1	135	university	university	PROPN
fnp-5721	1	136	of	of	ADP
fnp-5721	1	137	vienna	vienna	PROPN
fnp-5721	1	138	·	·	PUNCT
fnp-5721	1	139	1090	1090	NUM
fnp-5721	1	140	vienna	vienna	NOUN
fnp-5721	1	141	·	·	PUNCT
fnp-5721	1	142	austria	austria	PROPN
fnp-5721	1	143	ellen.gelpi@meduniwien.ac.at	ellen.gelpi@meduniwien.ac.at	NUM
fnp-5721	2	1	submitted	submit	VERB
fnp-5721	2	2	:	:	PUNCT
fnp-5721	2	3	29	29	NUM
fnp-5721	2	4	july	july	NOUN
fnp-5721	2	5	2024	2024	NUM
fnp-5721	2	6	accepted	accept	VERB
fnp-5721	2	7	:	:	PUNCT
fnp-5721	2	8	14	14	NUM
fnp-5721	2	9	september	september	PROPN
fnp-5721	2	10	2024	2024	NUM
fnp-5721	2	11	copyedited	copyedit	VERB
fnp-5721	2	12	by	by	ADP
fnp-5721	2	13	:	:	PUNCT
fnp-5721	2	14	georg	georg	NOUN
fnp-5721	2	15	haase	haase	NOUN
fnp-5721	2	16	published	publish	VERB
fnp-5721	2	17	:	:	PUNCT
fnp-5721	2	18	02	02	NUM
fnp-5721	2	19	october	october	PROPN
fnp-5721	2	20	2024	2024	NUM
fnp-5721	2	21	https://doi.org/10.17879/freeneuropathology-2024-5721	https://doi.org/10.17879/freeneuropathology-2024-5721	NOUN
fnp-5721	2	22	keywords	keyword	NOUN
fnp-5721	2	23	:	:	PUNCT
fnp-5721	2	24	neurofilament	neurofilament	ADJ
fnp-5721	2	25	inclusions	inclusion	NOUN
fnp-5721	2	26	,	,	PUNCT
fnp-5721	2	27	locus	locus	NOUN
fnp-5721	2	28	coeruleus	coeruleus	NOUN
fnp-5721	2	29	,	,	PUNCT
fnp-5721	2	30	neurofilament	neurofilament	NOUN
fnp-5721	2	31	,	,	PUNCT
fnp-5721	2	32	neuronal	neuronal	ADJ
fnp-5721	2	33	cytoplasmic	cytoplasmic	ADJ
fnp-5721	2	34	inclusion	inclusion	NOUN
fnp-5721	2	35	,	,	PUNCT
fnp-5721	2	36	creutzfeldt	creutzfeldt	ADJ
fnp-5721	2	37	-	-	PUNCT
fnp-5721	2	38	jakob	jakob	ADJ
fnp-5721	2	39	disease	disease	PROPN
fnp-5721	2	40	introduction	introduction	NOUN
fnp-5721	2	41	creutzfeldt	creutzfeldt	PROPN
fnp-5721	2	42	-	-	PUNCT
fnp-5721	2	43	jakob	jakob	ADJ
fnp-5721	2	44	disease	disease	NOUN
fnp-5721	2	45	(	(	PUNCT
fnp-5721	2	46	cjd	cjd	PROPN
fnp-5721	2	47	)	)	PUNCT
fnp-5721	2	48	is	be	AUX
fnp-5721	2	49	the	the	DET
fnp-5721	2	50	most	most	ADV
fnp-5721	2	51	frequent	frequent	ADJ
fnp-5721	2	52	human	human	ADJ
fnp-5721	2	53	prion	prion	NOUN
fnp-5721	2	54	disease	disease	NOUN
fnp-5721	2	55	,	,	PUNCT
fnp-5721	2	56	but	but	CCONJ
fnp-5721	2	57	it	it	PRON
fnp-5721	2	58	is	be	AUX
fnp-5721	2	59	overall	overall	ADV
fnp-5721	2	60	a	a	DET
fnp-5721	2	61	very	very	ADV
fnp-5721	2	62	rare	rare	ADJ
fnp-5721	2	63	,	,	PUNCT
fnp-5721	2	64	rapidly	rapidly	ADV
fnp-5721	2	65	progressive	progressive	ADJ
fnp-5721	2	66	neurodegenerative	neurodegenerative	ADJ
fnp-5721	2	67	disease.1	disease.1	PROPN
fnp-5721	2	68	physiopathologically	physiopathologically	NOUN
fnp-5721	2	69	,	,	PUNCT
fnp-5721	2	70	prion	prion	NOUN
fnp-5721	2	71	diseases	disease	NOUN
fnp-5721	2	72	have	have	AUX
fnp-5721	2	73	set	set	VERB
fnp-5721	2	74	the	the	DET
fnp-5721	2	75	basis	basis	NOUN
fnp-5721	2	76	for	for	ADP
fnp-5721	2	77	the	the	DET
fnp-5721	2	78	concept	concept	NOUN
fnp-5721	2	79	of	of	ADP
fnp-5721	2	80	protein	protein	NOUN
fnp-5721	2	81	misfolding	misfolde	VERB
fnp-5721	2	82	as	as	ADP
fnp-5721	2	83	a	a	DET
fnp-5721	2	84	common	common	ADJ
fnp-5721	2	85	mechanism	mechanism	NOUN
fnp-5721	2	86	for	for	ADP
fnp-5721	2	87	the	the	DET
fnp-5721	2	88	most	most	ADV
fnp-5721	2	89	prevalent	prevalent	ADJ
fnp-5721	2	90	protein	protein	NOUN
fnp-5721	2	91	-	-	PUNCT
fnp-5721	2	92	related	relate	VERB
fnp-5721	2	93	neurodegenerative	neurodegenerative	ADJ
fnp-5721	2	94	conditions	condition	NOUN
fnp-5721	2	95	.	.	PUNCT
fnp-5721	3	1	in	in	ADP
fnp-5721	3	2	addition	addition	NOUN
fnp-5721	3	3	,	,	PUNCT
fnp-5721	3	4	interactions	interaction	NOUN
fnp-5721	3	5	between	between	ADP
fnp-5721	3	6	misfolded	misfolde	VERB
fnp-5721	3	7	proteins	protein	NOUN
fnp-5721	3	8	have	have	AUX
fnp-5721	3	9	been	be	AUX
fnp-5721	3	10	an	an	DET
fnp-5721	3	11	intense	intense	ADJ
fnp-5721	3	12	topic	topic	NOUN
fnp-5721	3	13	of	of	ADP
fnp-5721	3	14	basic	basic	ADJ
fnp-5721	3	15	research	research	NOUN
fnp-5721	3	16	in	in	ADP
fnp-5721	3	17	the	the	DET
fnp-5721	3	18	field	field	NOUN
fnp-5721	3	19	of	of	ADP
fnp-5721	3	20	neurodegeneration	neurodegeneration	NOUN
fnp-5721	3	21	,	,	PUNCT
fnp-5721	3	22	as	as	SCONJ
fnp-5721	3	23	has	have	AUX
fnp-5721	3	24	been	be	AUX
fnp-5721	3	25	the	the	DET
fnp-5721	3	26	analysis	analysis	NOUN
fnp-5721	3	27	of	of	ADP
fnp-5721	3	28	concomitant	concomitant	ADJ
fnp-5721	3	29	“	"	PUNCT
fnp-5721	3	30	proteinopathies	proteinopathie	NOUN
fnp-5721	3	31	”	"	PUNCT
fnp-5721	3	32	in	in	ADP
fnp-5721	3	33	neuropathology	neuropathology	NOUN
fnp-5721	3	34	.	.	PUNCT
fnp-5721	4	1	several	several	ADJ
fnp-5721	4	2	cases	case	NOUN
fnp-5721	4	3	of	of	ADP
fnp-5721	4	4	cjd	cjd	NOUN
fnp-5721	4	5	featuring	feature	VERB
fnp-5721	4	6	concomitant	concomitant	ADJ
fnp-5721	4	7	pathologies	pathology	NOUN
fnp-5721	4	8	such	such	ADJ
fnp-5721	4	9	as	as	ADP
fnp-5721	4	10	alzheimer	alzheimer	PROPN
fnp-5721	4	11	’s	’s	PART
fnp-5721	4	12	disease	disease	NOUN
fnp-5721	4	13	1,2,3	1,2,3	NUM
fnp-5721	4	14	or	or	CCONJ
fnp-5721	4	15	lewy	lewy	ADJ
fnp-5721	4	16	body	body	NOUN
fnp-5721	4	17	dementia	dementia	NOUN
fnp-5721	4	18	4,5,6	4,5,6	NUM
fnp-5721	4	19	have	have	AUX
fnp-5721	4	20	been	be	AUX
fnp-5721	4	21	reported	report	VERB
fnp-5721	4	22	over	over	ADP
fnp-5721	4	23	the	the	DET
fnp-5721	4	24	last	last	ADJ
fnp-5721	4	25	years	year	NOUN
fnp-5721	4	26	.	.	PUNCT
fnp-5721	5	1	most	most	ADJ
fnp-5721	5	2	of	of	ADP
fnp-5721	5	3	the	the	DET
fnp-5721	5	4	concomitant	concomitant	ADJ
fnp-5721	5	5	pathologies	pathology	NOUN
fnp-5721	5	6	have	have	AUX
fnp-5721	5	7	been	be	AUX
fnp-5721	5	8	attributed	attribute	VERB
fnp-5721	5	9	to	to	ADP
fnp-5721	5	10	age	age	NOUN
fnp-5721	5	11	rather	rather	ADV
fnp-5721	5	12	than	than	ADP
fnp-5721	5	13	to	to	ADP
fnp-5721	5	14	a	a	DET
fnp-5721	5	15	direct	direct	ADJ
fnp-5721	5	16	effect	effect	NOUN
fnp-5721	5	17	of	of	ADP
fnp-5721	5	18	the	the	DET
fnp-5721	5	19	prion	prion	NOUN
fnp-5721	5	20	protein7,8	protein7,8	PROPN
fnp-5721	5	21	,	,	PUNCT
fnp-5721	5	22	although	although	SCONJ
fnp-5721	5	23	this	this	PRON
fnp-5721	5	24	is	be	AUX
fnp-5721	5	25	still	still	ADV
fnp-5721	5	26	controversial	controversial	ADJ
fnp-5721	5	27	.	.	PUNCT
fnp-5721	6	1	here	here	ADV
fnp-5721	6	2	we	we	PRON
fnp-5721	6	3	report	report	VERB
fnp-5721	6	4	the	the	DET
fnp-5721	6	5	neuropathological	neuropathological	ADJ
fnp-5721	6	6	findings	finding	NOUN
fnp-5721	6	7	of	of	ADP
fnp-5721	6	8	a	a	DET
fnp-5721	6	9	cjd	cjd	NOUN
fnp-5721	6	10	patient	patient	NOUN
fnp-5721	6	11	with	with	ADP
fnp-5721	6	12	striking	strike	VERB
fnp-5721	6	13	intraneuronal	intraneuronal	ADJ
fnp-5721	6	14	inclusions	inclusion	NOUN
fnp-5721	6	15	that	that	PRON
fnp-5721	6	16	are	be	AUX
fnp-5721	6	17	restricted	restrict	VERB
fnp-5721	6	18	to	to	ADP
fnp-5721	6	19	the	the	DET
fnp-5721	6	20	locus	locus	ADJ
fnp-5721	6	21	coeruleus	coeruleus	NOUN
fnp-5721	6	22	and	and	CCONJ
fnp-5721	6	23	that	that	PRON
fnp-5721	6	24	display	display	VERB
fnp-5721	6	25	a	a	DET
fnp-5721	6	26	unique	unique	ADJ
fnp-5721	6	27	immunohistochemical	immunohistochemical	ADJ
fnp-5721	6	28	profile	profile	NOUN
fnp-5721	6	29	not	not	PART
fnp-5721	6	30	seen	see	VERB
fnp-5721	6	31	in	in	ADP
fnp-5721	6	32	other	other	ADJ
fnp-5721	6	33	neurodegenerative	neurodegenerative	ADJ
fnp-5721	6	34	diseases	disease	NOUN
fnp-5721	6	35	.	.	PUNCT
fnp-5721	7	1	we	we	PRON
fnp-5721	7	2	propose	propose	VERB
fnp-5721	7	3	that	that	SCONJ
fnp-5721	7	4	these	these	DET
fnp-5721	7	5	unique	unique	ADJ
fnp-5721	7	6	intraneuronal	intraneuronal	ADJ
fnp-5721	7	7	inclusions	inclusion	NOUN
fnp-5721	7	8	might	might	AUX
fnp-5721	7	9	be	be	AUX
fnp-5721	7	10	associated	associate	VERB
fnp-5721	7	11	with	with	ADP
fnp-5721	7	12	subtle	subtle	ADJ
fnp-5721	7	13	and	and	CCONJ
fnp-5721	7	14	slowly	slowly	ADV
fnp-5721	7	15	progressing	progress	VERB
fnp-5721	7	16	neurological	neurological	ADJ
fnp-5721	7	17	symptoms	symptom	NOUN
fnp-5721	7	18	like	like	ADP
fnp-5721	7	19	rapid	rapid	ADJ
fnp-5721	7	20	-	-	PUNCT
fnp-5721	7	21	eye	eye	NOUN
fnp-5721	7	22	movement	movement	NOUN
fnp-5721	7	23	behavior	behavior	NOUN
fnp-5721	7	24	disorder	disorder	NOUN
fnp-5721	7	25	(	(	PUNCT
fnp-5721	7	26	rbd	rbd	NOUN
fnp-5721	7	27	)	)	PUNCT
fnp-5721	7	28	or	or	CCONJ
fnp-5721	7	29	reduced	reduce	VERB
fnp-5721	7	30	cognitive	cognitive	ADJ
fnp-5721	7	31	flexibility	flexibility	NOUN
fnp-5721	7	32	.	.	PUNCT
fnp-5721	8	1	case	case	NOUN
fnp-5721	8	2	presentation	presentation	NOUN
fnp-5721	8	3	the	the	DET
fnp-5721	8	4	patient	patient	NOUN
fnp-5721	8	5	was	be	AUX
fnp-5721	8	6	an	an	DET
fnp-5721	8	7	84	84	NUM
fnp-5721	8	8	-	-	PUNCT
fnp-5721	8	9	year	year	NOUN
fnp-5721	8	10	old	old	ADJ
fnp-5721	8	11	female	female	ADJ
fnp-5721	8	12	patient	patient	NOUN
fnp-5721	8	13	who	who	PRON
fnp-5721	8	14	developed	develop	VERB
fnp-5721	8	15	a	a	DET
fnp-5721	8	16	rapidly	rapidly	ADV
fnp-5721	8	17	progressive	progressive	ADJ
fnp-5721	8	18	dementia	dementia	NOUN
fnp-5721	8	19	accompanied	accompany	VERB
fnp-5721	8	20	by	by	ADP
fnp-5721	8	21	rigidity	rigidity	NOUN
fnp-5721	8	22	,	,	PUNCT
fnp-5721	8	23	dysarthria	dysarthria	NOUN
fnp-5721	8	24	and	and	CCONJ
fnp-5721	8	25	dysphagia	dysphagia	NOUN
fnp-5721	8	26	within	within	ADP
fnp-5721	8	27	a	a	DET
fnp-5721	8	28	few	few	ADJ
fnp-5721	8	29	months	month	NOUN
fnp-5721	8	30	.	.	PUNCT
fnp-5721	9	1	brain	brain	NOUN
fnp-5721	9	2	mri	mri	NOUN
fnp-5721	9	3	revealed	reveal	VERB
fnp-5721	9	4	a	a	DET
fnp-5721	9	5	restricted	restrict	VERB
fnp-5721	9	6	-	-	PUNCT
fnp-5721	9	7	diffusion	diffusion	NOUN
fnp-5721	9	8	pattern	pattern	NOUN
fnp-5721	9	9	of	of	ADP
fnp-5721	9	10	the	the	DET
fnp-5721	9	11	left	left	ADJ
fnp-5721	9	12	basal	basal	ADJ
fnp-5721	9	13	ganglia	ganglia	NOUN
fnp-5721	9	14	,	,	PUNCT
fnp-5721	9	15	and	and	CCONJ
fnp-5721	9	16	the	the	DET
fnp-5721	9	17	eeg	eeg	NOUN
fnp-5721	9	18	showed	show	VERB
fnp-5721	9	19	partially	partially	ADV
fnp-5721	9	20	steeply	steeply	ADV
fnp-5721	9	21	configured	configure	VERB
fnp-5721	9	22	signals	signal	NOUN
fnp-5721	9	23	.	.	PUNCT
fnp-5721	10	1	the	the	DET
fnp-5721	10	2	cerebrospinal	cerebrospinal	ADJ
fnp-5721	10	3	fluid	fluid	NOUN
fnp-5721	10	4	tests	test	NOUN
fnp-5721	10	5	revealed	reveal	VERB
fnp-5721	10	6	an	an	DET
fnp-5721	10	7	increased	increased	ADJ
fnp-5721	10	8	14	14	NUM
fnp-5721	10	9	-	-	SYM
fnp-5721	10	10	3	3	NUM
fnp-5721	10	11	-	-	SYM
fnp-5721	10	12	3	3	NUM
fnp-5721	10	13	protein	protein	NOUN
fnp-5721	10	14	concentration	concentration	NOUN
fnp-5721	10	15	of	of	ADP
fnp-5721	10	16	over	over	ADP
fnp-5721	10	17	80	80	NUM
fnp-5721	10	18	000	000	NUM
fnp-5721	10	19	au	au	NOUN
fnp-5721	10	20	/	/	SYM
fnp-5721	10	21	ml	ml	PROPN
fnp-5721	10	22	(	(	PUNCT
fnp-5721	10	23	reference	reference	NOUN
fnp-5721	10	24	values	value	VERB
fnp-5721	10	25	<	<	X
fnp-5721	10	26	 	 	SPACE
fnp-5721	10	27	10	10	NUM
fnp-5721	10	28	000	000	NUM
fnp-5721	10	29	au	au	NOUN
fnp-5721	10	30	/	/	SYM
fnp-5721	10	31	ml	ml	NOUN
fnp-5721	10	32	)	)	PUNCT
fnp-5721	10	33	and	and	CCONJ
fnp-5721	10	34	a	a	DET
fnp-5721	10	35	positive	positive	ADJ
fnp-5721	10	36	real	real	ADJ
fnp-5721	10	37	-	-	PUNCT
fnp-5721	10	38	time	time	NOUN
fnp-5721	10	39	quaking	quake	VERB
fnp-5721	10	40	-	-	PUNCT
fnp-5721	10	41	induced	induced	ADJ
fnp-5721	10	42	conversion	conversion	NOUN
fnp-5721	10	43	(	(	PUNCT
fnp-5721	10	44	rtquic	rtquic	NOUN
fnp-5721	10	45	)	)	PUNCT
fnp-5721	10	46	of	of	ADP
fnp-5721	10	47	the	the	DET
fnp-5721	10	48	prion	prion	NOUN
fnp-5721	10	49	protein	protein	NOUN
fnp-5721	10	50	(	(	PUNCT
fnp-5721	10	51	prp	prp	PROPN
fnp-5721	10	52	)	)	PUNCT
fnp-5721	10	53	.	.	PUNCT
fnp-5721	11	1	the	the	DET
fnp-5721	11	2	patient	patient	NOUN
fnp-5721	11	3	fulfilled	fulfil	VERB
fnp-5721	11	4	criteria	criterion	NOUN
fnp-5721	11	5	for	for	ADP
fnp-5721	11	6	“	"	PUNCT
fnp-5721	11	7	probable	probable	ADJ
fnp-5721	11	8	”	"	PUNCT
fnp-5721	11	9	creutzfeldt	creutzfeldt	ADJ
fnp-5721	11	10	-	-	PUNCT
fnp-5721	11	11	jakob	jakob	ADJ
fnp-5721	11	12	disease	disease	NOUN
fnp-5721	11	13	(	(	PUNCT
fnp-5721	11	14	cjd)9	cjd)9	PROPN
fnp-5721	11	15	and	and	CCONJ
fnp-5721	11	16	died	die	VERB
fnp-5721	11	17	within	within	ADP
fnp-5721	11	18	less	less	ADJ
fnp-5721	11	19	than	than	ADP
fnp-5721	11	20	4	4	NUM
fnp-5721	11	21	months	month	NOUN
fnp-5721	11	22	.	.	PUNCT
fnp-5721	12	1	the	the	DET
fnp-5721	12	2	brain	brain	NOUN
fnp-5721	12	3	weight	weight	NOUN
fnp-5721	12	4	was	be	AUX
fnp-5721	12	5	1275	1275	NUM
fnp-5721	12	6	gram	gram	NOUN
fnp-5721	12	7	.	.	PUNCT
fnp-5721	13	1	on	on	ADP
fnp-5721	13	2	gross	gross	ADJ
fnp-5721	13	3	examination	examination	NOUN
fnp-5721	13	4	,	,	PUNCT
fnp-5721	13	5	there	there	PRON
fnp-5721	13	6	were	be	VERB
fnp-5721	13	7	no	no	DET
fnp-5721	13	8	signs	sign	NOUN
fnp-5721	13	9	of	of	ADP
fnp-5721	13	10	brain	brain	NOUN
fnp-5721	13	11	atrophy	atrophy	NOUN
fnp-5721	13	12	.	.	PUNCT
fnp-5721	14	1	the	the	DET
fnp-5721	14	2	circulus	circulus	PROPN
fnp-5721	14	3	of	of	ADP
fnp-5721	14	4	willis	willis	PROPN
fnp-5721	14	5	showed	show	VERB
fnp-5721	14	6	only	only	ADV
fnp-5721	14	7	a	a	DET
fnp-5721	14	8	few	few	ADJ
fnp-5721	14	9	non	non	ADJ
fnp-5721	14	10	-	-	ADJ
fnp-5721	14	11	stenosing	stenosing	ADJ
fnp-5721	14	12	plaques	plaque	NOUN
fnp-5721	14	13	in	in	ADP
fnp-5721	14	14	the	the	DET
fnp-5721	14	15	arterial	arterial	NOUN
fnp-5721	14	16	wall	wall	NOUN
fnp-5721	14	17	.	.	PUNCT
fnp-5721	15	1	there	there	PRON
fnp-5721	15	2	were	be	VERB
fnp-5721	15	3	no	no	DET
fnp-5721	15	4	signs	sign	NOUN
fnp-5721	15	5	of	of	ADP
fnp-5721	15	6	brain	brain	NOUN
fnp-5721	15	7	swelling	swell	VERB
fnp-5721	15	8	with	with	ADP
fnp-5721	15	9	tonsillar	tonsillar	ADJ
fnp-5721	15	10	notch	notch	NOUN
fnp-5721	15	11	.	.	PUNCT
fnp-5721	16	1	the	the	DET
fnp-5721	16	2	ventricular	ventricular	ADJ
fnp-5721	16	3	system	system	NOUN
fnp-5721	16	4	was	be	AUX
fnp-5721	16	5	not	not	PART
fnp-5721	16	6	enlarged	enlarge	VERB
fnp-5721	16	7	.	.	PUNCT
fnp-5721	17	1	the	the	DET
fnp-5721	17	2	substantia	substantia	NOUN
fnp-5721	17	3	nigra	nigra	NOUN
fnp-5721	17	4	and	and	CCONJ
fnp-5721	17	5	locus	locus	NOUN
fnp-5721	17	6	coeruleus	coeruleus	NOUN
fnp-5721	17	7	appeared	appear	VERB
fnp-5721	17	8	to	to	PART
fnp-5721	17	9	be	be	AUX
fnp-5721	17	10	regularly	regularly	ADV
fnp-5721	17	11	pigmented	pigment	VERB
fnp-5721	17	12	.	.	PUNCT
fnp-5721	18	1	microscopic	microscopic	ADJ
fnp-5721	18	2	examination	examination	NOUN
fnp-5721	18	3	revealed	reveal	VERB
fnp-5721	18	4	the	the	DET
fnp-5721	18	5	spongiform	spongiform	NOUN
fnp-5721	18	6	neuropil	neuropil	PROPN
fnp-5721	18	7	change	change	NOUN
fnp-5721	18	8	characteristic	characteristic	ADJ
fnp-5721	18	9	of	of	ADP
fnp-5721	18	10	cjd10	cjd10	PROPN
fnp-5721	18	11	as	as	ADV
fnp-5721	18	12	well	well	ADV
fnp-5721	18	13	as	as	ADP
fnp-5721	18	14	nerve	nerve	NOUN
fnp-5721	18	15	cell	cell	NOUN
fnp-5721	18	16	loss	loss	NOUN
fnp-5721	18	17	and	and	CCONJ
fnp-5721	18	18	gliosis	gliosis	NOUN
fnp-5721	18	19	in	in	ADP
fnp-5721	18	20	the	the	DET
fnp-5721	18	21	deeper	deep	ADJ
fnp-5721	18	22	cortical	cortical	ADJ
fnp-5721	18	23	layers	layer	NOUN
fnp-5721	18	24	of	of	ADP
fnp-5721	18	25	the	the	DET
fnp-5721	18	26	frontal	frontal	ADJ
fnp-5721	18	27	and	and	CCONJ
fnp-5721	18	28	parietal	parietal	ADJ
fnp-5721	18	29	lobes	lobe	NOUN
fnp-5721	18	30	as	as	ADV
fnp-5721	18	31	well	well	ADV
fnp-5721	18	32	as	as	ADP
fnp-5721	18	33	in	in	ADP
fnp-5721	18	34	the	the	DET
fnp-5721	18	35	basal	basal	ADJ
fnp-5721	18	36	ganglia	ganglia	NOUN
fnp-5721	18	37	,	,	PUNCT
fnp-5721	18	38	thalamus	thalamus	NOUN
fnp-5721	18	39	,	,	PUNCT
fnp-5721	18	40	brainstem	brainstem	NOUN
fnp-5721	18	41	and	and	CCONJ
fnp-5721	18	42	cerebellum	cerebellum	ADJ
fnp-5721	18	43	.	.	PUNCT
fnp-5721	19	1	pathological	pathological	ADJ
fnp-5721	19	2	prion	prion	NOUN
fnp-5721	19	3	protein	protein	NOUN
fnp-5721	19	4	deposits	deposit	NOUN
fnp-5721	19	5	(	(	PUNCT
fnp-5721	19	6	anti	anti	ADJ
fnp-5721	19	7	-	-	ADJ
fnp-5721	19	8	prp	prp	ADJ
fnp-5721	19	9	,	,	PUNCT
fnp-5721	19	10	bertin	bertin	PROPN
fnp-5721	19	11	bioreagent	bioreagent	NOUN
fnp-5721	19	12	,	,	PUNCT
fnp-5721	19	13	12f10	12f10	NUM
fnp-5721	19	14	)	)	PUNCT
fnp-5721	19	15	were	be	AUX
fnp-5721	19	16	immunohistochemically	immunohistochemically	ADV
fnp-5721	19	17	detected	detect	VERB
fnp-5721	19	18	in	in	ADP
fnp-5721	19	19	these	these	DET
fnp-5721	19	20	regions	region	NOUN
fnp-5721	19	21	.	.	PUNCT
fnp-5721	20	1	in	in	ADP
fnp-5721	20	2	cortical	cortical	ADJ
fnp-5721	20	3	regions	region	NOUN
fnp-5721	20	4	,	,	PUNCT
fnp-5721	20	5	there	there	PRON
fnp-5721	20	6	was	be	VERB
fnp-5721	20	7	a	a	DET
fnp-5721	20	8	predominantly	predominantly	ADV
fnp-5721	20	9	deep	deep	ADJ
fnp-5721	20	10	-	-	PUNCT
fnp-5721	20	11	laminar	laminar	ADJ
fnp-5721	20	12	perineuronal	perineuronal	ADJ
fnp-5721	20	13	pattern	pattern	NOUN
fnp-5721	20	14	while	while	SCONJ
fnp-5721	20	15	the	the	DET
fnp-5721	20	16	basal	basal	ADJ
fnp-5721	20	17	ganglia	ganglia	NOUN
fnp-5721	20	18	,	,	PUNCT
fnp-5721	20	19	the	the	DET
fnp-5721	20	20	cerebellum	cerebellum	NOUN
fnp-5721	20	21	and	and	CCONJ
fnp-5721	20	22	the	the	DET
fnp-5721	20	23	nuclei	nucleus	NOUN
fnp-5721	20	24	of	of	ADP
fnp-5721	20	25	the	the	DET
fnp-5721	20	26	brainstem	brainstem	NOUN
fnp-5721	20	27	,	,	PUNCT
fnp-5721	20	28	including	include	VERB
fnp-5721	20	29	the	the	DET
fnp-5721	20	30	locus	locus	ADJ
fnp-5721	20	31	coeruleus	coeruleus	NOUN
fnp-5721	20	32	and	and	CCONJ
fnp-5721	20	33	the	the	DET
fnp-5721	20	34	solitary	solitary	ADJ
fnp-5721	20	35	tract	tract	NOUN
fnp-5721	20	36	showed	show	VERB
fnp-5721	20	37	a	a	DET
fnp-5721	20	38	dense	dense	ADJ
fnp-5721	20	39	synaptic	synaptic	ADJ
fnp-5721	20	40	deposition	deposition	NOUN
fnp-5721	20	41	pattern	pattern	NOUN
fnp-5721	20	42	.	.	PUNCT
fnp-5721	21	1	in	in	ADP
fnp-5721	21	2	addition	addition	NOUN
fnp-5721	21	3	,	,	PUNCT
fnp-5721	21	4	there	there	PRON
fnp-5721	21	5	were	be	VERB
fnp-5721	21	6	some	some	DET
fnp-5721	21	7	plaque	plaque	NOUN
fnp-5721	21	8	-	-	PUNCT
fnp-5721	21	9	like	like	ADJ
fnp-5721	21	10	deposits	deposit	NOUN
fnp-5721	21	11	in	in	ADP
fnp-5721	21	12	the	the	DET
fnp-5721	21	13	neighbouring	neighbouring	ADJ
fnp-5721	21	14	white	white	ADJ
fnp-5721	21	15	matter	matter	NOUN
fnp-5721	21	16	and	and	CCONJ
fnp-5721	21	17	also	also	ADV
fnp-5721	21	18	deposits	deposit	NOUN
fnp-5721	21	19	along	along	ADP
fnp-5721	21	20	axons	axon	NOUN
fnp-5721	21	21	and	and	CCONJ
fnp-5721	21	22	perivascularly	perivascularly	ADV
fnp-5721	21	23	in	in	ADP
fnp-5721	21	24	basal	basal	ADJ
fnp-5721	21	25	ganglia	ganglia	NOUN
fnp-5721	21	26	and	and	CCONJ
fnp-5721	21	27	thalamus	thalamus	NOUN
fnp-5721	21	28	.	.	PUNCT
fnp-5721	22	1	the	the	DET
fnp-5721	22	2	morphological	morphological	ADJ
fnp-5721	22	3	and	and	CCONJ
fnp-5721	22	4	immunohistochemical	immunohistochemical	ADJ
fnp-5721	22	5	distribution	distribution	NOUN
fnp-5721	22	6	pattern	pattern	NOUN
fnp-5721	22	7	was	be	AUX
fnp-5721	22	8	overall	overall	ADV
fnp-5721	22	9	well	well	ADV
fnp-5721	22	10	compatible	compatible	ADJ
fnp-5721	22	11	with	with	ADP
fnp-5721	22	12	the	the	DET
fnp-5721	22	13	vv2	vv2	PROPN
fnp-5721	22	14	histotype	histotype	NOUN
fnp-5721	22	15	according	accord	VERB
fnp-5721	22	16	to	to	ADP
fnp-5721	22	17	the	the	DET
fnp-5721	22	18	2009	2009	NUM
fnp-5721	22	19	parchi	parchi	NOUN
fnp-5721	22	20	classification	classification	NOUN
fnp-5721	22	21	of	of	ADP
fnp-5721	22	22	cjd	cjd	PROPN
fnp-5721	22	23	(	(	PUNCT
fnp-5721	22	24	figure	figure	NOUN
fnp-5721	22	25	1).11	1).11	NUM
fnp-5721	22	26	figure	figure	NOUN
fnp-5721	22	27	1	1	NUM
fnp-5721	22	28	.	.	PUNCT
fnp-5721	22	29	characteristic	characteristic	ADJ
fnp-5721	22	30	features	feature	NOUN
fnp-5721	22	31	of	of	ADP
fnp-5721	22	32	cjd	cjd	PROPN
fnp-5721	22	33	neuropathology	neuropathology	NOUN
fnp-5721	22	34	consistent	consistent	ADJ
fnp-5721	22	35	with	with	ADP
fnp-5721	22	36	the	the	DET
fnp-5721	22	37	vv2	vv2	PROPN
fnp-5721	22	38	histotype	histotype	PROPN
fnp-5721	22	39	a	a	DET
fnp-5721	22	40	,	,	PUNCT
fnp-5721	22	41	b	b	NOUN
fnp-5721	22	42	:	:	PUNCT
fnp-5721	22	43	immunohistochemistry	immunohistochemistry	NOUN
fnp-5721	22	44	for	for	ADP
fnp-5721	22	45	prp	prp	PROPN
fnp-5721	22	46	shows	show	VERB
fnp-5721	22	47	a	a	DET
fnp-5721	22	48	deep	deep	ADJ
fnp-5721	22	49	laminar	laminar	NOUN
fnp-5721	22	50	,	,	PUNCT
fnp-5721	22	51	perineuronal	perineuronal	ADJ
fnp-5721	22	52	deposition	deposition	NOUN
fnp-5721	22	53	pattern	pattern	NOUN
fnp-5721	22	54	.	.	PUNCT
fnp-5721	23	1	c	c	X
fnp-5721	23	2	,	,	PUNCT
fnp-5721	23	3	d	d	NOUN
fnp-5721	23	4	:	:	PUNCT
fnp-5721	23	5	in	in	ADP
fnp-5721	23	6	the	the	DET
fnp-5721	23	7	basal	basal	ADJ
fnp-5721	23	8	ganglia	ganglia	NOUN
fnp-5721	23	9	,	,	PUNCT
fnp-5721	23	10	spongiform	spongiform	NOUN
fnp-5721	23	11	change	change	NOUN
fnp-5721	23	12	is	be	AUX
fnp-5721	23	13	relatively	relatively	ADV
fnp-5721	23	14	prominent	prominent	ADJ
fnp-5721	23	15	(	(	PUNCT
fnp-5721	23	16	c	c	NOUN
fnp-5721	23	17	)	)	PUNCT
fnp-5721	23	18	and	and	CCONJ
fnp-5721	23	19	anti	anti	ADJ
fnp-5721	23	20	-	-	ADJ
fnp-5721	23	21	prp	prp	ADJ
fnp-5721	23	22	immunohistochemistry	immunohistochemistry	NOUN
fnp-5721	23	23	shows	show	VERB
fnp-5721	23	24	a	a	DET
fnp-5721	23	25	strong	strong	ADJ
fnp-5721	23	26	synaptic	synaptic	ADJ
fnp-5721	23	27	deposition	deposition	NOUN
fnp-5721	23	28	pattern	pattern	NOUN
fnp-5721	23	29	(	(	PUNCT
fnp-5721	23	30	d	d	NOUN
fnp-5721	23	31	)	)	PUNCT
fnp-5721	23	32	.	.	PUNCT
fnp-5721	24	1	e	e	X
fnp-5721	24	2	-	-	NOUN
fnp-5721	24	3	h	h	NOUN
fnp-5721	24	4	:	:	PUNCT
fnp-5721	24	5	in	in	ADP
fnp-5721	24	6	the	the	DET
fnp-5721	24	7	cerebellum	cerebellum	NOUN
fnp-5721	24	8	,	,	PUNCT
fnp-5721	24	9	spongiform	spongiform	NOUN
fnp-5721	24	10	change	change	NOUN
fnp-5721	24	11	is	be	AUX
fnp-5721	24	12	prominent	prominent	ADJ
fnp-5721	24	13	in	in	ADP
fnp-5721	24	14	the	the	DET
fnp-5721	24	15	molecular	molecular	ADJ
fnp-5721	24	16	layer	layer	NOUN
fnp-5721	24	17	and	and	CCONJ
fnp-5721	24	18	there	there	PRON
fnp-5721	24	19	is	be	VERB
fnp-5721	24	20	a	a	DET
fnp-5721	24	21	moderate	moderate	ADJ
fnp-5721	24	22	reduction	reduction	NOUN
fnp-5721	24	23	of	of	ADP
fnp-5721	24	24	granule	granule	NOUN
fnp-5721	24	25	cells	cell	NOUN
fnp-5721	24	26	(	(	PUNCT
fnp-5721	24	27	e	e	NOUN
fnp-5721	24	28	)	)	PUNCT
fnp-5721	24	29	.	.	PUNCT
fnp-5721	25	1	single	single	ADJ
fnp-5721	25	2	torpedoes	torpedo	NOUN
fnp-5721	25	3	are	be	AUX
fnp-5721	25	4	also	also	ADV
fnp-5721	25	5	observed	observe	VERB
fnp-5721	25	6	(	(	PUNCT
fnp-5721	25	7	g	g	NOUN
fnp-5721	25	8	)	)	PUNCT
fnp-5721	25	9	.	.	PUNCT
fnp-5721	26	1	immunohistochemistry	immunohistochemistry	NOUN
fnp-5721	26	2	for	for	ADP
fnp-5721	26	3	prp	prp	PROPN
fnp-5721	26	4	reveals	reveal	VERB
fnp-5721	26	5	pathological	pathological	ADJ
fnp-5721	26	6	synaptic	synaptic	ADJ
fnp-5721	26	7	deposits	deposit	NOUN
fnp-5721	26	8	in	in	ADP
fnp-5721	26	9	the	the	DET
fnp-5721	26	10	cerebellar	cerebellar	ADJ
fnp-5721	26	11	cortex	cortex	NOUN
fnp-5721	26	12	and	and	CCONJ
fnp-5721	26	13	coarse	coarse	VERB
fnp-5721	26	14	as	as	ADV
fnp-5721	26	15	well	well	ADV
fnp-5721	26	16	as	as	ADP
fnp-5721	26	17	plaque	plaque	NOUN
fnp-5721	26	18	-	-	PUNCT
fnp-5721	26	19	like	like	ADJ
fnp-5721	26	20	and	and	CCONJ
fnp-5721	26	21	periaxonal	periaxonal	ADJ
fnp-5721	26	22	aggregates	aggregate	NOUN
fnp-5721	26	23	in	in	ADP
fnp-5721	26	24	the	the	DET
fnp-5721	26	25	cerebellar	cerebellar	ADJ
fnp-5721	26	26	white	white	ADJ
fnp-5721	26	27	matter	matter	NOUN
fnp-5721	26	28	(	(	PUNCT
fnp-5721	26	29	h	h	NOUN
fnp-5721	26	30	)	)	PUNCT
fnp-5721	26	31	.	.	PUNCT
fnp-5721	27	1	synaptic	synaptic	ADJ
fnp-5721	27	2	pathological	pathological	ADJ
fnp-5721	27	3	prp	prp	NOUN
fnp-5721	27	4	deposits	deposit	NOUN
fnp-5721	27	5	were	be	AUX
fnp-5721	27	6	also	also	ADV
fnp-5721	27	7	detected	detect	VERB
fnp-5721	27	8	in	in	ADP
fnp-5721	27	9	the	the	DET
fnp-5721	27	10	brainstem	brainstem	NOUN
fnp-5721	27	11	including	include	VERB
fnp-5721	27	12	the	the	DET
fnp-5721	27	13	locus	locus	ADJ
fnp-5721	27	14	coeruleus	coeruleus	NOUN
fnp-5721	27	15	and	and	CCONJ
fnp-5721	27	16	solitary	solitary	ADJ
fnp-5721	27	17	nucleus	nucleus	NOUN
fnp-5721	27	18	(	(	PUNCT
fnp-5721	27	19	not	not	PART
fnp-5721	27	20	shown	show	VERB
fnp-5721	27	21	)	)	PUNCT
fnp-5721	27	22	.	.	PUNCT
fnp-5721	28	1	in	in	ADP
fnp-5721	28	2	addition	addition	NOUN
fnp-5721	28	3	to	to	ADP
fnp-5721	28	4	the	the	DET
fnp-5721	28	5	characteristic	characteristic	ADJ
fnp-5721	28	6	features	feature	NOUN
fnp-5721	28	7	of	of	ADP
fnp-5721	28	8	a	a	DET
fnp-5721	28	9	spongiform	spongiform	NOUN
fnp-5721	28	10	encephalopathy	encephalopathy	NOUN
fnp-5721	28	11	,	,	PUNCT
fnp-5721	28	12	several	several	ADJ
fnp-5721	28	13	fibrillar	fibrillar	ADJ
fnp-5721	28	14	neuronal	neuronal	ADJ
fnp-5721	28	15	inclusions	inclusion	NOUN
fnp-5721	28	16	restricted	restrict	VERB
fnp-5721	28	17	to	to	ADP
fnp-5721	28	18	the	the	DET
fnp-5721	28	19	locus	locus	ADJ
fnp-5721	28	20	coeruleus	coeruleus	NOUN
fnp-5721	28	21	(	(	PUNCT
fnp-5721	28	22	lc	lc	NOUN
fnp-5721	28	23	)	)	PUNCT
fnp-5721	28	24	were	be	AUX
fnp-5721	28	25	identified	identify	VERB
fnp-5721	28	26	in	in	ADP
fnp-5721	28	27	this	this	DET
fnp-5721	28	28	patient	patient	NOUN
fnp-5721	28	29	.	.	PUNCT
fnp-5721	29	1	the	the	DET
fnp-5721	29	2	locus	locus	NOUN
fnp-5721	29	3	coeruleus	coeruleus	NOUN
fnp-5721	29	4	showed	show	VERB
fnp-5721	29	5	a	a	DET
fnp-5721	29	6	moderate	moderate	ADJ
fnp-5721	29	7	reduction	reduction	NOUN
fnp-5721	29	8	of	of	ADP
fnp-5721	29	9	pigmented	pigmented	ADJ
fnp-5721	29	10	neurons	neuron	NOUN
fnp-5721	29	11	and	and	CCONJ
fnp-5721	29	12	an	an	DET
fnp-5721	29	13	accompanying	accompanying	ADJ
fnp-5721	29	14	gliosis	gliosis	NOUN
fnp-5721	29	15	.	.	PUNCT
fnp-5721	30	1	the	the	DET
fnp-5721	30	2	inclusions	inclusion	NOUN
fnp-5721	30	3	were	be	AUX
fnp-5721	30	4	relatively	relatively	ADV
fnp-5721	30	5	large	large	ADJ
fnp-5721	30	6	,	,	PUNCT
fnp-5721	30	7	partly	partly	ADV
fnp-5721	30	8	eosinophilic	eosinophilic	ADJ
fnp-5721	30	9	and	and	CCONJ
fnp-5721	30	10	partly	partly	ADV
fnp-5721	30	11	pale	pale	ADJ
fnp-5721	30	12	basophilic	basophilic	NOUN
fnp-5721	30	13	on	on	ADP
fnp-5721	30	14	h	h	NOUN
fnp-5721	30	15	 	 	SPACE
fnp-5721	30	16	&	&	CCONJ
fnp-5721	30	17	 	 	SPACE
fnp-5721	30	18	e	e	ADJ
fnp-5721	30	19	-	-	ADJ
fnp-5721	30	20	stained	stain	VERB
fnp-5721	30	21	sections	section	NOUN
fnp-5721	30	22	and	and	CCONJ
fnp-5721	30	23	partly	partly	ADV
fnp-5721	30	24	argyrophilic	argyrophilic	ADJ
fnp-5721	30	25	on	on	ADP
fnp-5721	30	26	bielschowskyand	bielschowskyand	NOUN
fnp-5721	30	27	gallyas	gallyas	PROPN
fnp-5721	30	28	silver	silver	NOUN
fnp-5721	30	29	impregnation	impregnation	NOUN
fnp-5721	30	30	methods	method	NOUN
fnp-5721	30	31	(	(	PUNCT
fnp-5721	30	32	figure	figure	NOUN
fnp-5721	30	33	2	2	NUM
fnp-5721	30	34	)	)	PUNCT
fnp-5721	30	35	.	.	PUNCT
fnp-5721	31	1	in	in	ADP
fnp-5721	31	2	contrast	contrast	NOUN
fnp-5721	31	3	,	,	PUNCT
fnp-5721	31	4	by	by	ADP
fnp-5721	31	5	fluorescence	fluorescence	NOUN
fnp-5721	31	6	microscopy	microscopy	NOUN
fnp-5721	31	7	,	,	PUNCT
fnp-5721	31	8	only	only	ADV
fnp-5721	31	9	a	a	DET
fnp-5721	31	10	small	small	ADJ
fnp-5721	31	11	fraction	fraction	NOUN
fnp-5721	31	12	of	of	ADP
fnp-5721	31	13	the	the	DET
fnp-5721	31	14	inclusions	inclusion	NOUN
fnp-5721	31	15	was	be	AUX
fnp-5721	31	16	weakly	weakly	ADJ
fnp-5721	31	17	and	and	CCONJ
fnp-5721	31	18	irregularly	irregularly	ADV
fnp-5721	31	19	stained	stain	VERB
fnp-5721	31	20	by	by	ADP
fnp-5721	31	21	thioflavin	thioflavin	PROPN
fnp-5721	31	22	t	t	PROPN
fnp-5721	31	23	,	,	PUNCT
fnp-5721	31	24	while	while	SCONJ
fnp-5721	31	25	the	the	DET
fnp-5721	31	26	majority	majority	NOUN
fnp-5721	31	27	of	of	ADP
fnp-5721	31	28	inclusions	inclusion	NOUN
fnp-5721	31	29	was	be	AUX
fnp-5721	31	30	not	not	PART
fnp-5721	31	31	stained	stain	VERB
fnp-5721	31	32	by	by	ADP
fnp-5721	31	33	thioflavin	thioflavin	PROPN
fnp-5721	31	34	t.	t.	PROPN
fnp-5721	31	35	figure	figure	NOUN
fnp-5721	31	36	2	2	NUM
fnp-5721	31	37	.	.	PUNCT
fnp-5721	31	38	microscopic	microscopic	ADJ
fnp-5721	31	39	features	feature	NOUN
fnp-5721	31	40	of	of	ADP
fnp-5721	31	41	intraneuronal	intraneuronal	ADJ
fnp-5721	31	42	cytoplasmic	cytoplasmic	ADJ
fnp-5721	31	43	inclusions	inclusion	NOUN
fnp-5721	31	44	in	in	ADP
fnp-5721	31	45	the	the	DET
fnp-5721	31	46	locus	locus	ADJ
fnp-5721	31	47	coeruleus	coeruleus	NOUN
fnp-5721	31	48	a	a	NOUN
fnp-5721	31	49	-	-	PUNCT
fnp-5721	31	50	c	c	NOUN
fnp-5721	31	51	:	:	PUNCT
fnp-5721	31	52	frequent	frequent	ADJ
fnp-5721	31	53	filamentous	filamentous	ADJ
fnp-5721	31	54	intraneuronal	intraneuronal	ADJ
fnp-5721	31	55	cytoplasmic	cytoplasmic	ADJ
fnp-5721	31	56	inclusions	inclusion	NOUN
fnp-5721	31	57	in	in	ADP
fnp-5721	31	58	the	the	DET
fnp-5721	31	59	locus	locus	NOUN
fnp-5721	31	60	coeruleus	coeruleus	NOUN
fnp-5721	31	61	after	after	SCONJ
fnp-5721	31	62	hematoxylin	hematoxylin	NOUN
fnp-5721	31	63	-	-	PUNCT
fnp-5721	31	64	eosin	eosin	NOUN
fnp-5721	31	65	staining	stain	VERB
fnp-5721	31	66	.	.	PUNCT
fnp-5721	32	1	note	note	VERB
fnp-5721	32	2	the	the	DET
fnp-5721	32	3	large	large	ADJ
fnp-5721	32	4	size	size	NOUN
fnp-5721	32	5	and	and	CCONJ
fnp-5721	32	6	the	the	DET
fnp-5721	32	7	variable	variable	ADJ
fnp-5721	32	8	morphology	morphology	NOUN
fnp-5721	32	9	of	of	ADP
fnp-5721	32	10	the	the	DET
fnp-5721	32	11	inclusions	inclusion	NOUN
fnp-5721	32	12	that	that	PRON
fnp-5721	32	13	range	range	VERB
fnp-5721	32	14	from	from	ADP
fnp-5721	32	15	pale	pale	ADJ
fnp-5721	32	16	basophilic	basophilic	ADJ
fnp-5721	32	17	and	and	CCONJ
fnp-5721	32	18	fibrillar	fibrillar	ADJ
fnp-5721	32	19	to	to	ADP
fnp-5721	32	20	dense	dense	ADJ
fnp-5721	32	21	hyaline	hyaline	NOUN
fnp-5721	32	22	and	and	CCONJ
fnp-5721	32	23	eosinophilic	eosinophilic	NOUN
fnp-5721	32	24	.	.	PUNCT
fnp-5721	33	1	d	d	X
fnp-5721	33	2	-	-	PUNCT
fnp-5721	33	3	e	e	NOUN
fnp-5721	33	4	:	:	PUNCT
fnp-5721	33	5	p62	p62	NOUN
fnp-5721	33	6	highlights	highlight	VERB
fnp-5721	33	7	the	the	DET
fnp-5721	33	8	compact	compact	ADJ
fnp-5721	33	9	and	and	CCONJ
fnp-5721	33	10	filamentous	filamentous	ADJ
fnp-5721	33	11	nature	nature	NOUN
fnp-5721	33	12	of	of	ADP
fnp-5721	33	13	the	the	DET
fnp-5721	33	14	large	large	ADJ
fnp-5721	33	15	neuronal	neuronal	ADJ
fnp-5721	33	16	inclusions	inclusion	NOUN
fnp-5721	33	17	.	.	PUNCT
fnp-5721	34	1	f	f	X
fnp-5721	34	2	:	:	PUNCT
fnp-5721	34	3	intraneuronal	intraneuronal	ADJ
fnp-5721	34	4	inclusions	inclusion	NOUN
fnp-5721	34	5	were	be	AUX
fnp-5721	34	6	negative	negative	ADJ
fnp-5721	34	7	for	for	ADP
fnp-5721	34	8	alpha	alpha	NOUN
fnp-5721	34	9	-	-	PUNCT
fnp-5721	34	10	synuclein	synuclein	NOUN
fnp-5721	34	11	,	,	PUNCT
fnp-5721	34	12	tau	tau	PROPN
fnp-5721	34	13	,	,	PUNCT
fnp-5721	34	14	phosphorylated	phosphorylate	VERB
fnp-5721	34	15	tdp-43	tdp-43	NOUN
fnp-5721	34	16	and	and	CCONJ
fnp-5721	34	17	fus	fus	PROPN
fnp-5721	34	18	(	(	PUNCT
fnp-5721	34	19	arrows	arrow	NOUN
fnp-5721	34	20	denote	denote	VERB
fnp-5721	34	21	negative	negative	ADJ
fnp-5721	34	22	inclusion	inclusion	NOUN
fnp-5721	34	23	)	)	PUNCT
fnp-5721	34	24	.	.	PUNCT
fnp-5721	35	1	g	g	PROPN
fnp-5721	35	2	-	-	PUNCT
fnp-5721	35	3	i	i	NOUN
fnp-5721	35	4	:	:	PUNCT
fnp-5721	35	5	in	in	ADP
fnp-5721	35	6	contrast	contrast	NOUN
fnp-5721	35	7	,	,	PUNCT
fnp-5721	35	8	neuronal	neuronal	ADJ
fnp-5721	35	9	inclusions	inclusion	NOUN
fnp-5721	35	10	were	be	AUX
fnp-5721	35	11	positive	positive	ADJ
fnp-5721	35	12	for	for	ADP
fnp-5721	35	13	phosphorylated	phosphorylate	VERB
fnp-5721	35	14	neurofilaments	neurofilament	NOUN
fnp-5721	35	15	(	(	PUNCT
fnp-5721	35	16	smi31	smi31	NOUN
fnp-5721	35	17	,	,	PUNCT
fnp-5721	35	18	g	g	NOUN
fnp-5721	35	19	,	,	PUNCT
fnp-5721	35	20	arrow	arrow	NOUN
fnp-5721	35	21	points	point	NOUN
fnp-5721	35	22	to	to	ADP
fnp-5721	35	23	a	a	DET
fnp-5721	35	24	non	non	ADJ
fnp-5721	35	25	-	-	ADJ
fnp-5721	35	26	stained	stained	ADJ
fnp-5721	35	27	segment	segment	NOUN
fnp-5721	35	28	of	of	ADP
fnp-5721	35	29	a	a	DET
fnp-5721	35	30	large	large	ADJ
fnp-5721	35	31	fibrillar	fibrillar	ADJ
fnp-5721	35	32	inclusion	inclusion	NOUN
fnp-5721	35	33	)	)	PUNCT
fnp-5721	35	34	and	and	CCONJ
fnp-5721	35	35	non	non	ADJ
fnp-5721	35	36	-	-	ADJ
fnp-5721	35	37	phosphorylated	phosphorylate	VERB
fnp-5721	35	38	neurofilaments	neurofilament	NOUN
fnp-5721	35	39	(	(	PUNCT
fnp-5721	35	40	smi32	smi32	PROPN
fnp-5721	35	41	,	,	PUNCT
fnp-5721	35	42	h	h	NOUN
fnp-5721	35	43	,	,	PUNCT
fnp-5721	35	44	i	i	PROPN
fnp-5721	35	45	)	)	PUNCT
fnp-5721	35	46	.	.	PUNCT
fnp-5721	36	1	j	j	PROPN
fnp-5721	36	2	-	-	PUNCT
fnp-5721	36	3	l	l	NOUN
fnp-5721	36	4	:	:	PUNCT
fnp-5721	36	5	the	the	DET
fnp-5721	36	6	inclusions	inclusion	NOUN
fnp-5721	36	7	were	be	AUX
fnp-5721	36	8	partly	partly	ADV
fnp-5721	36	9	argyrophilic	argyrophilic	ADJ
fnp-5721	36	10	(	(	PUNCT
fnp-5721	36	11	j	j	PROPN
fnp-5721	36	12	,	,	PUNCT
fnp-5721	36	13	k	k	NOUN
fnp-5721	36	14	)	)	PUNCT
fnp-5721	36	15	and	and	CCONJ
fnp-5721	36	16	strongly	strongly	ADV
fnp-5721	36	17	positive	positive	ADJ
fnp-5721	36	18	for	for	ADP
fnp-5721	36	19	alpha	alpha	NOUN
fnp-5721	36	20	-	-	NOUN
fnp-5721	36	21	internexin	internexin	PROPN
fnp-5721	36	22	(	(	PUNCT
fnp-5721	36	23	l	l	NOUN
fnp-5721	36	24	)	)	PUNCT
fnp-5721	36	25	.	.	PUNCT
fnp-5721	37	1	immunohistochemically	immunohistochemically	ADV
fnp-5721	37	2	,	,	PUNCT
fnp-5721	37	3	the	the	DET
fnp-5721	37	4	neuronal	neuronal	ADJ
fnp-5721	37	5	inclusions	inclusion	NOUN
fnp-5721	37	6	in	in	ADP
fnp-5721	37	7	the	the	DET
fnp-5721	37	8	lc	lc	NOUN
fnp-5721	37	9	were	be	AUX
fnp-5721	37	10	immunoreactive	immunoreactive	ADJ
fnp-5721	37	11	for	for	ADP
fnp-5721	37	12	p62	p62	NOUN
fnp-5721	37	13	,	,	PUNCT
fnp-5721	37	14	an	an	DET
fnp-5721	37	15	indicator	indicator	NOUN
fnp-5721	37	16	of	of	ADP
fnp-5721	37	17	autophagic	autophagic	ADJ
fnp-5721	37	18	degradative	degradative	ADJ
fnp-5721	37	19	activity	activity	NOUN
fnp-5721	37	20	and	and	CCONJ
fnp-5721	37	21	they	they	PRON
fnp-5721	37	22	were	be	AUX
fnp-5721	37	23	strongly	strongly	ADV
fnp-5721	37	24	immunoreactive	immunoreactive	ADJ
fnp-5721	37	25	for	for	ADP
fnp-5721	37	26	phosphorylated	phosphorylate	VERB
fnp-5721	37	27	neurofilaments	neurofilament	NOUN
fnp-5721	37	28	(	(	PUNCT
fnp-5721	37	29	biolegend	biolegend	NOUN
fnp-5721	37	30	,	,	PUNCT
fnp-5721	37	31	clone	clone	NOUN
fnp-5721	37	32	smi	smi	PROPN
fnp-5721	37	33	 	 	SPACE
fnp-5721	37	34	31	31	NUM
fnp-5721	37	35	)	)	PUNCT
fnp-5721	37	36	,	,	PUNCT
fnp-5721	37	37	non	non	ADJ
fnp-5721	37	38	-	-	ADJ
fnp-5721	37	39	phosphorylated	phosphorylate	VERB
fnp-5721	37	40	neurofilaments	neurofilament	NOUN
fnp-5721	37	41	(	(	PUNCT
fnp-5721	37	42	biolegend	biolegend	NOUN
fnp-5721	37	43	,	,	PUNCT
fnp-5721	37	44	clone	clone	NOUN
fnp-5721	37	45	smi	smi	PROPN
fnp-5721	37	46	 	 	SPACE
fnp-5721	37	47	32	32	NUM
fnp-5721	37	48	)	)	PUNCT
fnp-5721	37	49	and	and	CCONJ
fnp-5721	37	50	alpha	alpha	NOUN
fnp-5721	37	51	-	-	PUNCT
fnp-5721	37	52	internexin	internexin	PROPN
fnp-5721	37	53	(	(	PUNCT
fnp-5721	37	54	invitrogen	invitrogen	PROPN
fnp-5721	37	55	,	,	PUNCT
fnp-5721	37	56	clone	clone	NOUN
fnp-5721	37	57	2e3	2e3	NUM
fnp-5721	37	58	)	)	PUNCT
fnp-5721	37	59	,	,	PUNCT
fnp-5721	37	60	a	a	DET
fnp-5721	37	61	class	class	NOUN
fnp-5721	37	62	iv	iv	NUM
fnp-5721	37	63	neuronal	neuronal	ADJ
fnp-5721	37	64	intermediate	intermediate	ADJ
fnp-5721	37	65	filament	filament	NOUN
fnp-5721	37	66	.	.	PUNCT
fnp-5721	38	1	although	although	SCONJ
fnp-5721	38	2	the	the	DET
fnp-5721	38	3	histological	histological	ADJ
fnp-5721	38	4	and	and	CCONJ
fnp-5721	38	5	immunohistochemical	immunohistochemical	ADJ
fnp-5721	38	6	profile	profile	NOUN
fnp-5721	38	7	of	of	ADP
fnp-5721	38	8	these	these	DET
fnp-5721	38	9	neuronal	neuronal	ADJ
fnp-5721	38	10	inclusions	inclusion	NOUN
fnp-5721	38	11	strongly	strongly	ADV
fnp-5721	38	12	resembled	resemble	VERB
fnp-5721	38	13	that	that	SCONJ
fnp-5721	38	14	of	of	ADP
fnp-5721	38	15	neurofibrillary	neurofibrillary	ADJ
fnp-5721	38	16	tangles	tangle	NOUN
fnp-5721	38	17	,	,	PUNCT
fnp-5721	38	18	immunohistochemistry	immunohistochemistry	NOUN
fnp-5721	38	19	for	for	ADP
fnp-5721	38	20	phospho	phospho	NOUN
fnp-5721	38	21	-	-	PUNCT
fnp-5721	38	22	tau	tau	NOUN
fnp-5721	38	23	(	(	PUNCT
fnp-5721	38	24	thermo	thermo	NOUN
fnp-5721	38	25	scientific	scientific	PROPN
fnp-5721	38	26	,	,	PUNCT
fnp-5721	38	27	at8	at8	PROPN
fnp-5721	38	28	)	)	PUNCT
fnp-5721	38	29	remained	remain	VERB
fnp-5721	38	30	negative	negative	ADJ
fnp-5721	38	31	.	.	PUNCT
fnp-5721	39	1	immunostaining	immunostaine	VERB
fnp-5721	39	2	against	against	ADP
fnp-5721	39	3	alpha	alpha	NOUN
fnp-5721	39	4	-	-	PUNCT
fnp-5721	39	5	synuclein	synuclein	NOUN
fnp-5721	39	6	(	(	PUNCT
fnp-5721	39	7	ajroboscreen	ajroboscreen	ADJ
fnp-5721	39	8	,	,	PUNCT
fnp-5721	39	9	clone	clone	NOUN
fnp-5721	39	10	5g4	5g4	NUM
fnp-5721	39	11	)	)	PUNCT
fnp-5721	39	12	,	,	PUNCT
fnp-5721	39	13	ptdp43	ptdp43	NOUN
fnp-5721	39	14	(	(	PUNCT
fnp-5721	39	15	cosmobio	cosmobio	ADV
fnp-5721	39	16	,	,	PUNCT
fnp-5721	39	17	clone	clone	NOUN
fnp-5721	39	18	11/9	11/9	NUM
fnp-5721	39	19	)	)	PUNCT
fnp-5721	39	20	and	and	CCONJ
fnp-5721	39	21	fus	fus	INTJ
fnp-5721	39	22	(	(	PUNCT
fnp-5721	39	23	sigma	sigma	PROPN
fnp-5721	39	24	life	life	NOUN
fnp-5721	39	25	science	science	NOUN
fnp-5721	39	26	,	,	PUNCT
fnp-5721	39	27	clone	clone	NOUN
fnp-5721	39	28	g75241	g75241	NOUN
fnp-5721	39	29	)	)	PUNCT
fnp-5721	39	30	were	be	AUX
fnp-5721	39	31	also	also	ADV
fnp-5721	39	32	negative	negative	ADJ
fnp-5721	39	33	.	.	PUNCT
fnp-5721	40	1	interestingly	interestingly	ADV
fnp-5721	40	2	,	,	PUNCT
fnp-5721	40	3	these	these	DET
fnp-5721	40	4	fibrillar	fibrillar	ADJ
fnp-5721	40	5	inclusions	inclusion	NOUN
fnp-5721	40	6	were	be	AUX
fnp-5721	40	7	not	not	PART
fnp-5721	40	8	found	find	VERB
fnp-5721	40	9	in	in	ADP
fnp-5721	40	10	any	any	DET
fnp-5721	40	11	other	other	ADJ
fnp-5721	40	12	areas	area	NOUN
fnp-5721	40	13	of	of	ADP
fnp-5721	40	14	the	the	DET
fnp-5721	40	15	brain	brain	NOUN
fnp-5721	40	16	and	and	CCONJ
fnp-5721	40	17	were	be	AUX
fnp-5721	40	18	exclusively	exclusively	ADV
fnp-5721	40	19	identified	identify	VERB
fnp-5721	40	20	in	in	ADP
fnp-5721	40	21	the	the	DET
fnp-5721	40	22	lc	lc	PROPN
fnp-5721	40	23	.	.	PUNCT
fnp-5721	41	1	discussion	discussion	NOUN
fnp-5721	41	2	we	we	PRON
fnp-5721	41	3	present	present	VERB
fnp-5721	41	4	a	a	DET
fnp-5721	41	5	unique	unique	ADJ
fnp-5721	41	6	combination	combination	NOUN
fnp-5721	41	7	of	of	ADP
fnp-5721	41	8	sporadic	sporadic	ADJ
fnp-5721	41	9	cjd	cjd	NOUN
fnp-5721	41	10	with	with	ADP
fnp-5721	41	11	striking	strike	VERB
fnp-5721	41	12	neurofilamentous	neurofilamentous	ADJ
fnp-5721	41	13	inclusions	inclusion	NOUN
fnp-5721	41	14	restricted	restrict	VERB
fnp-5721	41	15	to	to	ADP
fnp-5721	41	16	the	the	DET
fnp-5721	41	17	locus	locus	NOUN
fnp-5721	41	18	coeruleus	coeruleus	NOUN
fnp-5721	41	19	.	.	PUNCT
fnp-5721	42	1	this	this	DET
fnp-5721	42	2	combination	combination	NOUN
fnp-5721	42	3	has	have	AUX
fnp-5721	42	4	not	not	PART
fnp-5721	42	5	been	be	AUX
fnp-5721	42	6	described	describe	VERB
fnp-5721	42	7	so	so	ADV
fnp-5721	42	8	far	far	ADV
fnp-5721	42	9	,	,	PUNCT
fnp-5721	42	10	and	and	CCONJ
fnp-5721	42	11	particularly	particularly	ADV
fnp-5721	42	12	,	,	PUNCT
fnp-5721	42	13	this	this	DET
fnp-5721	42	14	type	type	NOUN
fnp-5721	42	15	of	of	ADP
fnp-5721	42	16	neurofilament	neurofilament	NOUN
fnp-5721	42	17	-	-	PUNCT
fnp-5721	42	18	bearing	bear	VERB
fnp-5721	42	19	inclusions	inclusion	NOUN
fnp-5721	42	20	restricted	restrict	VERB
fnp-5721	42	21	to	to	ADP
fnp-5721	42	22	the	the	DET
fnp-5721	42	23	locus	locus	NOUN
fnp-5721	42	24	coeruleus	coeruleus	NOUN
fnp-5721	42	25	seems	seem	VERB
fnp-5721	42	26	to	to	PART
fnp-5721	42	27	be	be	AUX
fnp-5721	42	28	a	a	DET
fnp-5721	42	29	singular	singular	ADJ
fnp-5721	42	30	finding	finding	NOUN
fnp-5721	42	31	.	.	PUNCT
fnp-5721	43	1	the	the	DET
fnp-5721	43	2	significance	significance	NOUN
fnp-5721	43	3	of	of	ADP
fnp-5721	43	4	the	the	DET
fnp-5721	43	5	inclusion	inclusion	NOUN
fnp-5721	43	6	bodies	body	NOUN
fnp-5721	43	7	in	in	ADP
fnp-5721	43	8	this	this	DET
fnp-5721	43	9	region	region	NOUN
fnp-5721	43	10	is	be	AUX
fnp-5721	43	11	unclear	unclear	ADJ
fnp-5721	43	12	and	and	CCONJ
fnp-5721	43	13	no	no	DET
fnp-5721	43	14	obvious	obvious	ADJ
fnp-5721	43	15	clinical	clinical	ADJ
fnp-5721	43	16	correlate	correlate	NOUN
fnp-5721	43	17	could	could	AUX
fnp-5721	43	18	be	be	AUX
fnp-5721	43	19	retrospectively	retrospectively	ADV
fnp-5721	43	20	extrapolated	extrapolate	VERB
fnp-5721	43	21	from	from	ADP
fnp-5721	43	22	the	the	DET
fnp-5721	43	23	history	history	NOUN
fnp-5721	43	24	of	of	ADP
fnp-5721	43	25	the	the	DET
fnp-5721	43	26	patient	patient	NOUN
fnp-5721	43	27	,	,	PUNCT
fnp-5721	43	28	as	as	SCONJ
fnp-5721	43	29	symptoms	symptom	NOUN
fnp-5721	43	30	were	be	AUX
fnp-5721	43	31	dominated	dominate	VERB
fnp-5721	43	32	by	by	ADP
fnp-5721	43	33	the	the	DET
fnp-5721	43	34	rapidly	rapidly	ADV
fnp-5721	43	35	progressive	progressive	ADJ
fnp-5721	43	36	dementia	dementia	NOUN
fnp-5721	43	37	as	as	ADV
fnp-5721	43	38	well	well	ADV
fnp-5721	43	39	as	as	ADP
fnp-5721	43	40	the	the	DET
fnp-5721	43	41	brainstem	brainstem	NOUN
fnp-5721	43	42	and	and	CCONJ
fnp-5721	43	43	cerebellar	cerebellar	ADJ
fnp-5721	43	44	symptoms	symptom	NOUN
fnp-5721	43	45	of	of	ADP
fnp-5721	43	46	cjd	cjd	PROPN
fnp-5721	43	47	.	.	PUNCT
fnp-5721	44	1	of	of	ADP
fnp-5721	44	2	note	note	NOUN
fnp-5721	44	3	,	,	PUNCT
fnp-5721	44	4	some	some	DET
fnp-5721	44	5	important	important	ADJ
fnp-5721	44	6	functions	function	NOUN
fnp-5721	44	7	have	have	AUX
fnp-5721	44	8	been	be	AUX
fnp-5721	44	9	attributed	attribute	VERB
fnp-5721	44	10	to	to	ADP
fnp-5721	44	11	the	the	DET
fnp-5721	44	12	locus	locus	NOUN
fnp-5721	44	13	coeruleus	coeruleus	NOUN
fnp-5721	44	14	.	.	PUNCT
fnp-5721	45	1	the	the	DET
fnp-5721	45	2	pigmented	pigment	VERB
fnp-5721	45	3	neurons	neuron	NOUN
fnp-5721	45	4	in	in	ADP
fnp-5721	45	5	the	the	DET
fnp-5721	45	6	pontine	pontine	ADJ
fnp-5721	45	7	tegmentum	tegmentum	NOUN
fnp-5721	45	8	have	have	VERB
fnp-5721	45	9	highly	highly	ADV
fnp-5721	45	10	branched	branched	ADJ
fnp-5721	45	11	axon	axon	NOUN
fnp-5721	45	12	terminals	terminal	NOUN
fnp-5721	45	13	that	that	PRON
fnp-5721	45	14	innervate	innervate	VERB
fnp-5721	45	15	many	many	ADJ
fnp-5721	45	16	different	different	ADJ
fnp-5721	45	17	areas	area	NOUN
fnp-5721	45	18	of	of	ADP
fnp-5721	45	19	the	the	DET
fnp-5721	45	20	cns	cns	NOUN
fnp-5721	45	21	,	,	PUNCT
fnp-5721	45	22	including	include	VERB
fnp-5721	45	23	the	the	DET
fnp-5721	45	24	neocortex	neocortex	NOUN
fnp-5721	45	25	,	,	PUNCT
fnp-5721	45	26	hippocampus	hippocampus	NOUN
fnp-5721	45	27	,	,	PUNCT
fnp-5721	45	28	amygdala	amygdala	NOUN
fnp-5721	45	29	,	,	PUNCT
fnp-5721	45	30	thalamus	thalamus	NOUN
fnp-5721	45	31	,	,	PUNCT
fnp-5721	45	32	cerebellum	cerebellum	NOUN
fnp-5721	45	33	and	and	CCONJ
fnp-5721	45	34	spinal	spinal	ADJ
fnp-5721	45	35	cord	cord	NOUN
fnp-5721	45	36	and	and	CCONJ
fnp-5721	45	37	plays	play	VERB
fnp-5721	45	38	a	a	DET
fnp-5721	45	39	decisive	decisive	ADJ
fnp-5721	45	40	role	role	NOUN
fnp-5721	45	41	in	in	ADP
fnp-5721	45	42	arousal	arousal	NOUN
fnp-5721	45	43	,	,	PUNCT
fnp-5721	45	44	concentration	concentration	NOUN
fnp-5721	45	45	and	and	CCONJ
fnp-5721	45	46	stress	stress	NOUN
fnp-5721	45	47	response	response	NOUN
fnp-5721	45	48	as	as	SCONJ
fnp-5721	45	49	it	it	PRON
fnp-5721	45	50	is	be	AUX
fnp-5721	45	51	the	the	DET
fnp-5721	45	52	most	most	ADV
fnp-5721	45	53	important	important	ADJ
fnp-5721	45	54	source	source	NOUN
fnp-5721	45	55	of	of	ADP
fnp-5721	45	56	norepinephrine	norepinephrine	NOUN
fnp-5721	45	57	in	in	ADP
fnp-5721	45	58	the	the	DET
fnp-5721	45	59	cns.12	cns.12	NOUN
fnp-5721	45	60	the	the	DET
fnp-5721	45	61	locus	locus	ADJ
fnp-5721	45	62	coeruleus	coeruleus	NOUN
fnp-5721	45	63	seems	seem	VERB
fnp-5721	45	64	to	to	PART
fnp-5721	45	65	be	be	AUX
fnp-5721	45	66	prone	prone	ADJ
fnp-5721	45	67	to	to	ADP
fnp-5721	45	68	the	the	DET
fnp-5721	45	69	development	development	NOUN
fnp-5721	45	70	of	of	ADP
fnp-5721	45	71	certain	certain	ADJ
fnp-5721	45	72	types	type	NOUN
fnp-5721	45	73	of	of	ADP
fnp-5721	45	74	intraneuronal	intraneuronal	ADJ
fnp-5721	45	75	inclusions	inclusion	NOUN
fnp-5721	45	76	,	,	PUNCT
fnp-5721	45	77	particularly	particularly	ADV
fnp-5721	45	78	neurofibrillary	neurofibrillary	ADJ
fnp-5721	45	79	tangles	tangle	NOUN
fnp-5721	45	80	and	and	CCONJ
fnp-5721	45	81	lewy	lewy	ADJ
fnp-5721	45	82	bodies	body	NOUN
fnp-5721	45	83	,	,	PUNCT
fnp-5721	45	84	and	and	CCONJ
fnp-5721	45	85	its	its	PRON
fnp-5721	45	86	cells	cell	NOUN
fnp-5721	45	87	are	be	AUX
fnp-5721	45	88	affected	affect	VERB
fnp-5721	45	89	in	in	ADP
fnp-5721	45	90	various	various	ADJ
fnp-5721	45	91	neurodegenerative	neurodegenerative	ADJ
fnp-5721	45	92	conditions.13	conditions.13	NOUN
fnp-5721	45	93	in	in	ADP
fnp-5721	45	94	parkinson	parkinson	NOUN
fnp-5721	45	95	's	's	PART
fnp-5721	45	96	disease	disease	NOUN
fnp-5721	45	97	or	or	CCONJ
fnp-5721	45	98	lewy	lewy	ADJ
fnp-5721	45	99	body	body	NOUN
fnp-5721	45	100	dementia	dementia	NOUN
fnp-5721	45	101	,	,	PUNCT
fnp-5721	45	102	alpha	alpha	NOUN
fnp-5721	45	103	-	-	PUNCT
fnp-5721	45	104	synuclein	synuclein	NOUN
fnp-5721	45	105	aggregates	aggregate	NOUN
fnp-5721	45	106	in	in	ADP
fnp-5721	45	107	form	form	NOUN
fnp-5721	45	108	of	of	ADP
fnp-5721	45	109	lewy	lewy	ADJ
fnp-5721	45	110	bodies	body	NOUN
fnp-5721	45	111	and	and	CCONJ
fnp-5721	45	112	lewy	lewy	PROPN
fnp-5721	45	113	neurites	neurite	NOUN
fnp-5721	45	114	occur	occur	VERB
fnp-5721	45	115	in	in	ADP
fnp-5721	45	116	the	the	DET
fnp-5721	45	117	locus	locus	ADJ
fnp-5721	45	118	coeruleus	coeruleus	NOUN
fnp-5721	45	119	prior	prior	ADV
fnp-5721	45	120	to	to	ADP
fnp-5721	45	121	the	the	DET
fnp-5721	45	122	substantia	substantia	NOUN
fnp-5721	45	123	nigra.14	nigra.14	VERB
fnp-5721	45	124	the	the	DET
fnp-5721	45	125	neuronal	neuronal	ADJ
fnp-5721	45	126	dysfunction	dysfunction	NOUN
fnp-5721	45	127	of	of	ADP
fnp-5721	45	128	the	the	DET
fnp-5721	45	129	locus	locus	NOUN
fnp-5721	45	130	coeruleus	coeruleus	NOUN
fnp-5721	45	131	/	/	SYM
fnp-5721	45	132	subcoeruleus	subcoeruleus	NOUN
fnp-5721	45	133	also	also	ADV
fnp-5721	45	134	plays	play	VERB
fnp-5721	45	135	a	a	DET
fnp-5721	45	136	role	role	NOUN
fnp-5721	45	137	,	,	PUNCT
fnp-5721	45	138	together	together	ADV
fnp-5721	45	139	with	with	ADP
fnp-5721	45	140	the	the	DET
fnp-5721	45	141	gigantocellular	gigantocellular	ADJ
fnp-5721	45	142	nucleus	nucleus	NOUN
fnp-5721	45	143	of	of	ADP
fnp-5721	45	144	the	the	DET
fnp-5721	45	145	formatio	formatio	PROPN
fnp-5721	45	146	reticularis	reticularis	PROPN
fnp-5721	45	147	,	,	PUNCT
fnp-5721	45	148	in	in	ADP
fnp-5721	45	149	the	the	DET
fnp-5721	45	150	development	development	NOUN
fnp-5721	45	151	of	of	ADP
fnp-5721	45	152	rapid	rapid	ADJ
fnp-5721	45	153	-	-	PUNCT
fnp-5721	45	154	eye	eye	NOUN
fnp-5721	45	155	movement	movement	NOUN
fnp-5721	45	156	behavior	behavior	NOUN
fnp-5721	45	157	disorder	disorder	NOUN
fnp-5721	45	158	(	(	PUNCT
fnp-5721	45	159	rbd	rbd	NOUN
fnp-5721	45	160	)	)	PUNCT
fnp-5721	45	161	,	,	PUNCT
fnp-5721	45	162	a	a	DET
fnp-5721	45	163	disorder	disorder	NOUN
fnp-5721	45	164	in	in	ADP
fnp-5721	45	165	which	which	PRON
fnp-5721	45	166	atonia	atonia	NOUN
fnp-5721	45	167	lacks	lack	VERB
fnp-5721	45	168	during	during	ADP
fnp-5721	45	169	rem	rem	NOUN
fnp-5721	45	170	sleep	sleep	NOUN
fnp-5721	45	171	,	,	PUNCT
fnp-5721	45	172	leading	lead	VERB
fnp-5721	45	173	to	to	ADP
fnp-5721	45	174	dream	dream	NOUN
fnp-5721	45	175	-	-	PUNCT
fnp-5721	45	176	enacting	enact	VERB
fnp-5721	45	177	behavior	behavior	NOUN
fnp-5721	45	178	with	with	ADP
fnp-5721	45	179	flapping	flap	VERB
fnp-5721	45	180	,	,	PUNCT
fnp-5721	45	181	kicking	kicking	NOUN
fnp-5721	45	182	and	and	CCONJ
fnp-5721	45	183	biting.15,16,17	biting.15,16,17	NOUN
fnp-5721	45	184	rbd	rbd	NOUN
fnp-5721	45	185	most	most	ADV
fnp-5721	45	186	often	often	ADV
fnp-5721	45	187	represents	represent	VERB
fnp-5721	45	188	an	an	DET
fnp-5721	45	189	early	early	ADJ
fnp-5721	45	190	or	or	CCONJ
fnp-5721	45	191	even	even	ADV
fnp-5721	45	192	prodromal	prodromal	ADJ
fnp-5721	45	193	symptom	symptom	NOUN
fnp-5721	45	194	of	of	ADP
fnp-5721	45	195	parkinson	parkinson	NOUN
fnp-5721	45	196	's	's	PART
fnp-5721	45	197	disease18	disease18	NOUN
fnp-5721	45	198	or	or	CCONJ
fnp-5721	45	199	lewy	lewy	ADJ
fnp-5721	45	200	body	body	NOUN
fnp-5721	45	201	dementia	dementia	NOUN
fnp-5721	45	202	and	and	CCONJ
fnp-5721	45	203	is	be	AUX
fnp-5721	45	204	less	less	ADV
fnp-5721	45	205	often	often	ADV
fnp-5721	45	206	encountered	encounter	VERB
fnp-5721	45	207	in	in	ADP
fnp-5721	45	208	multisystem	multisystem	NOUN
fnp-5721	45	209	atrophy	atrophy	NOUN
fnp-5721	45	210	.	.	PUNCT
fnp-5721	46	1	rbd	rbd	NOUN
fnp-5721	46	2	is	be	AUX
fnp-5721	46	3	most	most	ADV
fnp-5721	46	4	frequently	frequently	ADV
fnp-5721	46	5	associated	associate	VERB
fnp-5721	46	6	with	with	ADP
fnp-5721	46	7	alpha	alpha	NOUN
fnp-5721	46	8	-	-	PUNCT
fnp-5721	46	9	synuclein	synuclein	NOUN
fnp-5721	46	10	pathology	pathology	PROPN
fnp-5721	46	11	.	.	PUNCT
fnp-5721	47	1	synuclein	synuclein	PROPN
fnp-5721	47	2	aggregates	aggregate	NOUN
fnp-5721	47	3	were	be	AUX
fnp-5721	47	4	however	however	ADV
fnp-5721	47	5	not	not	PART
fnp-5721	47	6	observed	observe	VERB
fnp-5721	47	7	in	in	ADP
fnp-5721	47	8	our	our	PRON
fnp-5721	47	9	patient	patient	NOUN
fnp-5721	47	10	.	.	PUNCT
fnp-5721	48	1	while	while	SCONJ
fnp-5721	48	2	we	we	PRON
fnp-5721	48	3	have	have	VERB
fnp-5721	48	4	no	no	DET
fnp-5721	48	5	definite	definite	ADJ
fnp-5721	48	6	data	datum	NOUN
fnp-5721	48	7	on	on	ADP
fnp-5721	48	8	whether	whether	SCONJ
fnp-5721	48	9	the	the	DET
fnp-5721	48	10	patient	patient	NOUN
fnp-5721	48	11	had	have	AUX
fnp-5721	48	12	rbd	rbd	NOUN
fnp-5721	48	13	or	or	CCONJ
fnp-5721	48	14	not	not	PART
fnp-5721	48	15	,	,	PUNCT
fnp-5721	48	16	the	the	DET
fnp-5721	48	17	large	large	ADJ
fnp-5721	48	18	neurofilament	neurofilament	ADJ
fnp-5721	48	19	inclusions	inclusion	NOUN
fnp-5721	48	20	in	in	ADP
fnp-5721	48	21	the	the	DET
fnp-5721	48	22	locus	locus	NOUN
fnp-5721	48	23	coeruleus	coeruleus	NOUN
fnp-5721	48	24	could	could	AUX
fnp-5721	48	25	theoretically	theoretically	ADV
fnp-5721	48	26	be	be	AUX
fnp-5721	48	27	an	an	DET
fnp-5721	48	28	additional	additional	ADJ
fnp-5721	48	29	non	non	ADJ
fnp-5721	48	30	-	-	ADJ
fnp-5721	48	31	lb	lb	ADV
fnp-5721	48	32	related	related	ADJ
fnp-5721	48	33	cause	cause	NOUN
fnp-5721	48	34	of	of	ADP
fnp-5721	48	35	rbd	rbd	NOUN
fnp-5721	48	36	.	.	PUNCT
fnp-5721	49	1	moreover	moreover	ADV
fnp-5721	49	2	,	,	PUNCT
fnp-5721	49	3	reduced	reduced	ADJ
fnp-5721	49	4	cognitive	cognitive	ADJ
fnp-5721	49	5	flexibility	flexibility	NOUN
fnp-5721	49	6	in	in	ADP
fnp-5721	49	7	pd	pd	PROPN
fnp-5721	49	8	has	have	AUX
fnp-5721	49	9	been	be	AUX
fnp-5721	49	10	related	relate	VERB
fnp-5721	49	11	to	to	ADP
fnp-5721	49	12	reduced	reduce	VERB
fnp-5721	49	13	neuromodulation	neuromodulation	NOUN
fnp-5721	49	14	of	of	ADP
fnp-5721	49	15	the	the	DET
fnp-5721	49	16	prefrontal	prefrontal	ADJ
fnp-5721	49	17	cortex	cortex	NOUN
fnp-5721	49	18	from	from	ADP
fnp-5721	49	19	subcortical	subcortical	ADJ
fnp-5721	49	20	structures	structure	NOUN
fnp-5721	49	21	such	such	ADJ
fnp-5721	49	22	as	as	ADP
fnp-5721	49	23	the	the	DET
fnp-5721	49	24	locus	locus	NOUN
fnp-5721	49	25	coeruleus.19	coeruleus.19	VERB
fnp-5721	49	26	these	these	DET
fnp-5721	49	27	symptoms	symptom	NOUN
fnp-5721	49	28	are	be	AUX
fnp-5721	49	29	however	however	ADV
fnp-5721	49	30	very	very	ADV
fnp-5721	49	31	difficult	difficult	ADJ
fnp-5721	49	32	to	to	PART
fnp-5721	49	33	assess	assess	VERB
fnp-5721	49	34	retrospectively	retrospectively	ADV
fnp-5721	49	35	and	and	CCONJ
fnp-5721	49	36	separate	separate	ADJ
fnp-5721	49	37	from	from	ADP
fnp-5721	49	38	the	the	DET
fnp-5721	49	39	development	development	NOUN
fnp-5721	49	40	of	of	ADP
fnp-5721	49	41	cjd	cjd	PROPN
fnp-5721	49	42	in	in	ADP
fnp-5721	49	43	our	our	PRON
fnp-5721	49	44	patient	patient	NOUN
fnp-5721	49	45	.	.	PUNCT
fnp-5721	50	1	concerning	concern	VERB
fnp-5721	50	2	prion	prion	NOUN
fnp-5721	50	3	diseases	disease	NOUN
fnp-5721	50	4	,	,	PUNCT
fnp-5721	50	5	experimental	experimental	ADJ
fnp-5721	50	6	studies	study	NOUN
fnp-5721	50	7	in	in	ADP
fnp-5721	50	8	mice	mouse	NOUN
fnp-5721	50	9	have	have	AUX
fnp-5721	50	10	shown	show	VERB
fnp-5721	50	11	that	that	SCONJ
fnp-5721	50	12	the	the	DET
fnp-5721	50	13	locus	locus	NOUN
fnp-5721	50	14	coeruleus	coeruleus	NOUN
fnp-5721	50	15	,	,	PUNCT
fnp-5721	50	16	the	the	DET
fnp-5721	50	17	solitary	solitary	ADJ
fnp-5721	50	18	tract	tract	NOUN
fnp-5721	50	19	and	and	CCONJ
fnp-5721	50	20	the	the	DET
fnp-5721	50	21	pre	pre	ADJ
fnp-5721	50	22	-	-	ADJ
fnp-5721	50	23	boetzinger	boetzinger	NOUN
fnp-5721	50	24	complex	complex	NOUN
fnp-5721	50	25	are	be	AUX
fnp-5721	50	26	the	the	DET
fnp-5721	50	27	first	first	ADJ
fnp-5721	50	28	brainstem	brainstem	NOUN
fnp-5721	50	29	target	target	NOUN
fnp-5721	50	30	areas	area	NOUN
fnp-5721	50	31	of	of	ADP
fnp-5721	50	32	early	early	ADJ
fnp-5721	50	33	prion	prion	NOUN
fnp-5721	50	34	deposition.20	deposition.20	NOUN
fnp-5721	50	35	interestingly	interestingly	ADV
fnp-5721	50	36	,	,	PUNCT
fnp-5721	50	37	the	the	DET
fnp-5721	50	38	vv2	vv2	NOUN
fnp-5721	50	39	subtype	subtype	NOUN
fnp-5721	50	40	of	of	ADP
fnp-5721	50	41	cjd	cjd	NOUN
fnp-5721	50	42	also	also	ADV
fnp-5721	50	43	involves	involve	VERB
fnp-5721	50	44	these	these	DET
fnp-5721	50	45	brain	brain	NOUN
fnp-5721	50	46	regions	region	NOUN
fnp-5721	50	47	,	,	PUNCT
fnp-5721	50	48	which	which	PRON
fnp-5721	50	49	all	all	PRON
fnp-5721	50	50	showed	show	VERB
fnp-5721	50	51	pathological	pathological	ADJ
fnp-5721	50	52	prp	prp	NOUN
fnp-5721	50	53	deposits	deposit	NOUN
fnp-5721	50	54	in	in	ADP
fnp-5721	50	55	our	our	PRON
fnp-5721	50	56	case	case	NOUN
fnp-5721	50	57	.	.	PUNCT
fnp-5721	51	1	neurofilament	neurofilament	ADJ
fnp-5721	51	2	inclusions	inclusion	NOUN
fnp-5721	51	3	are	be	AUX
fnp-5721	51	4	the	the	DET
fnp-5721	51	5	hallmark	hallmark	NOUN
fnp-5721	51	6	of	of	ADP
fnp-5721	51	7	neuronal	neuronal	ADJ
fnp-5721	51	8	intermediate	intermediate	ADJ
fnp-5721	51	9	filament	filament	NOUN
fnp-5721	51	10	inclusion	inclusion	NOUN
fnp-5721	51	11	disease	disease	NOUN
fnp-5721	51	12	(	(	PUNCT
fnp-5721	51	13	nifid	nifid	ADJ
fnp-5721	51	14	)	)	PUNCT
fnp-5721	51	15	,	,	PUNCT
fnp-5721	51	16	as	as	SCONJ
fnp-5721	51	17	described	describe	VERB
fnp-5721	51	18	by	by	ADP
fnp-5721	51	19	cairns	cairns	PROPN
fnp-5721	51	20	et	et	PROPN
fnp-5721	51	21	al.21	al.21	PROPN
fnp-5721	51	22	in	in	ADP
fnp-5721	51	23	patients	patient	NOUN
fnp-5721	51	24	with	with	ADP
fnp-5721	51	25	frontotemporal	frontotemporal	ADJ
fnp-5721	51	26	dementia	dementia	NOUN
fnp-5721	51	27	.	.	PUNCT
fnp-5721	52	1	in	in	ADP
fnp-5721	52	2	these	these	DET
fnp-5721	52	3	cases	case	NOUN
fnp-5721	52	4	however	however	ADV
fnp-5721	52	5	,	,	PUNCT
fnp-5721	52	6	the	the	DET
fnp-5721	52	7	morphology	morphology	NOUN
fnp-5721	52	8	and	and	CCONJ
fnp-5721	52	9	particularly	particularly	ADV
fnp-5721	52	10	the	the	DET
fnp-5721	52	11	extent	extent	NOUN
fnp-5721	52	12	of	of	ADP
fnp-5721	52	13	the	the	DET
fnp-5721	52	14	inclusions	inclusion	NOUN
fnp-5721	52	15	are	be	AUX
fnp-5721	52	16	very	very	ADV
fnp-5721	52	17	different	different	ADJ
fnp-5721	52	18	and	and	CCONJ
fnp-5721	52	19	affect	affect	VERB
fnp-5721	52	20	also	also	ADV
fnp-5721	52	21	cortical	cortical	ADJ
fnp-5721	52	22	areas	area	NOUN
fnp-5721	52	23	,	,	PUNCT
fnp-5721	52	24	in	in	ADP
fnp-5721	52	25	particular	particular	ADJ
fnp-5721	52	26	fronto	fronto	NOUN
fnp-5721	52	27	-	-	PUNCT
fnp-5721	52	28	temporal	temporal	ADJ
fnp-5721	52	29	regions	region	NOUN
fnp-5721	52	30	,	,	PUNCT
fnp-5721	52	31	basal	basal	ADJ
fnp-5721	52	32	ganglia	ganglia	NOUN
fnp-5721	52	33	,	,	PUNCT
fnp-5721	52	34	amygdala	amygdala	NOUN
fnp-5721	52	35	,	,	PUNCT
fnp-5721	52	36	hippocampus	hippocampus	NOUN
fnp-5721	52	37	,	,	PUNCT
fnp-5721	52	38	brainstem	brainstem	NOUN
fnp-5721	52	39	including	include	VERB
fnp-5721	52	40	the	the	DET
fnp-5721	52	41	substantia	substantia	NOUN
fnp-5721	52	42	nigra	nigra	NOUN
fnp-5721	52	43	,	,	PUNCT
fnp-5721	52	44	and	and	CCONJ
fnp-5721	52	45	cerebellum	cerebellum	NOUN
fnp-5721	52	46	.	.	PUNCT
fnp-5721	53	1	the	the	DET
fnp-5721	53	2	neurofilament	neurofilament	ADJ
fnp-5721	53	3	inclusions	inclusion	NOUN
fnp-5721	53	4	were	be	AUX
fnp-5721	53	5	originally	originally	ADV
fnp-5721	53	6	described	describe	VERB
fnp-5721	53	7	as	as	ADP
fnp-5721	53	8	alpha	alpha	NOUN
fnp-5721	53	9	-	-	PUNCT
fnp-5721	53	10	internexin	internexin	NOUN
fnp-5721	53	11	positive	positive	ADJ
fnp-5721	53	12	and	and	CCONJ
fnp-5721	53	13	are	be	AUX
fnp-5721	53	14	currently	currently	ADV
fnp-5721	53	15	considered	consider	VERB
fnp-5721	53	16	as	as	ADP
fnp-5721	53	17	a	a	DET
fnp-5721	53	18	subtype	subtype	NOUN
fnp-5721	53	19	of	of	ADP
fnp-5721	53	20	fus	fus	PROPN
fnp-5721	53	21	/	/	SYM
fnp-5721	53	22	fet	fet	PROPN
fnp-5721	53	23	proteinopathy.22	proteinopathy.22	NOUN
fnp-5721	53	24	in	in	ADP
fnp-5721	53	25	our	our	PRON
fnp-5721	53	26	case	case	NOUN
fnp-5721	53	27	,	,	PUNCT
fnp-5721	53	28	inclusions	inclusion	NOUN
fnp-5721	53	29	were	be	AUX
fnp-5721	53	30	positive	positive	ADJ
fnp-5721	53	31	for	for	ADP
fnp-5721	53	32	alpha	alpha	NOUN
fnp-5721	53	33	-	-	PUNCT
fnp-5721	53	34	internexin	internexin	PROPN
fnp-5721	53	35	,	,	PUNCT
fnp-5721	53	36	negative	negative	ADJ
fnp-5721	53	37	for	for	ADP
fnp-5721	53	38	fus	fus	PROPN
fnp-5721	53	39	and	and	CCONJ
fnp-5721	53	40	in	in	ADP
fnp-5721	53	41	the	the	DET
fnp-5721	53	42	majority	majority	NOUN
fnp-5721	53	43	negative	negative	ADJ
fnp-5721	53	44	for	for	ADP
fnp-5721	53	45	thioflavin	thioflavin	PROPN
fnp-5721	53	46	t.	t.	PROPN
fnp-5721	53	47	while	while	SCONJ
fnp-5721	53	48	thioflavin	thioflavin	PROPN
fnp-5721	53	49	t	t	PROPN
fnp-5721	53	50	is	be	AUX
fnp-5721	53	51	a	a	DET
fnp-5721	53	52	dye	dye	NOUN
fnp-5721	53	53	that	that	PRON
fnp-5721	53	54	binds	bind	VERB
fnp-5721	53	55	to	to	ADP
fnp-5721	53	56	β	β	NOUN
fnp-5721	53	57	-	-	ADJ
fnp-5721	53	58	sheet	sheet	ADJ
fnp-5721	53	59	rich	rich	ADJ
fnp-5721	53	60	structures	structure	NOUN
fnp-5721	53	61	,	,	PUNCT
fnp-5721	53	62	it	it	PRON
fnp-5721	53	63	may	may	AUX
fnp-5721	53	64	show	show	VERB
fnp-5721	53	65	variable	variable	ADJ
fnp-5721	53	66	affinity	affinity	NOUN
fnp-5721	53	67	for	for	ADP
fnp-5721	53	68	different	different	ADJ
fnp-5721	53	69	amyloid	amyloid	NOUN
fnp-5721	53	70	fibres	fibre	NOUN
fnp-5721	53	71	.	.	PUNCT
fnp-5721	54	1	whether	whether	SCONJ
fnp-5721	54	2	the	the	DET
fnp-5721	54	3	pale	pale	ADJ
fnp-5721	54	4	and	and	CCONJ
fnp-5721	54	5	irregular	irregular	ADJ
fnp-5721	54	6	thioflavin	thioflavin	PROPN
fnp-5721	54	7	t	t	PROPN
fnp-5721	54	8	staining	stain	VERB
fnp-5721	54	9	of	of	ADP
fnp-5721	54	10	some	some	DET
fnp-5721	54	11	intraneuronal	intraneuronal	ADJ
fnp-5721	54	12	neurofilament	neurofilament	ADJ
fnp-5721	54	13	inclusions	inclusion	NOUN
fnp-5721	54	14	and	and	CCONJ
fnp-5721	54	15	the	the	DET
fnp-5721	54	16	negative	negative	ADJ
fnp-5721	54	17	thioflavin	thioflavin	PROPN
fnp-5721	54	18	t	t	PROPN
fnp-5721	54	19	staining	stain	VERB
fnp-5721	54	20	in	in	ADP
fnp-5721	54	21	other	other	ADJ
fnp-5721	54	22	inclusions	inclusion	NOUN
fnp-5721	54	23	reflect	reflect	VERB
fnp-5721	54	24	different	different	ADJ
fnp-5721	54	25	fibrillation	fibrillation	NOUN
fnp-5721	54	26	states	state	NOUN
fnp-5721	54	27	and/or	and/or	CCONJ
fnp-5721	54	28	affinities	affinity	NOUN
fnp-5721	54	29	of	of	ADP
fnp-5721	54	30	the	the	DET
fnp-5721	54	31	aggregated	aggregate	VERB
fnp-5721	54	32	protein	protein	NOUN
fnp-5721	54	33	to	to	ADP
fnp-5721	54	34	the	the	DET
fnp-5721	54	35	dye	dye	NOUN
fnp-5721	54	36	is	be	AUX
fnp-5721	54	37	currently	currently	ADV
fnp-5721	54	38	unclear	unclear	ADJ
fnp-5721	54	39	.	.	PUNCT
fnp-5721	55	1	in	in	ADP
fnp-5721	55	2	summary	summary	NOUN
fnp-5721	55	3	,	,	PUNCT
fnp-5721	55	4	we	we	PRON
fnp-5721	55	5	report	report	VERB
fnp-5721	55	6	on	on	ADP
fnp-5721	55	7	a	a	DET
fnp-5721	55	8	patient	patient	NOUN
fnp-5721	55	9	who	who	PRON
fnp-5721	55	10	,	,	PUNCT
fnp-5721	55	11	in	in	ADP
fnp-5721	55	12	addition	addition	NOUN
fnp-5721	55	13	to	to	ADP
fnp-5721	55	14	cjd	cjd	PROPN
fnp-5721	55	15	,	,	PUNCT
fnp-5721	55	16	presented	present	VERB
fnp-5721	55	17	an	an	DET
fnp-5721	55	18	additional	additional	ADJ
fnp-5721	55	19	and	and	CCONJ
fnp-5721	55	20	likely	likely	ADJ
fnp-5721	55	21	independent	independent	ADJ
fnp-5721	55	22	neuropathological	neuropathological	ADJ
fnp-5721	55	23	alteration	alteration	NOUN
fnp-5721	55	24	.	.	PUNCT
fnp-5721	56	1	the	the	DET
fnp-5721	56	2	strict	strict	ADJ
fnp-5721	56	3	limitation	limitation	NOUN
fnp-5721	56	4	of	of	ADP
fnp-5721	56	5	the	the	DET
fnp-5721	56	6	large	large	ADJ
fnp-5721	56	7	neurofilamentous	neurofilamentous	ADJ
fnp-5721	56	8	inclusions	inclusion	NOUN
fnp-5721	56	9	to	to	ADP
fnp-5721	56	10	the	the	DET
fnp-5721	56	11	locus	locus	NOUN
fnp-5721	56	12	coeruleus	coeruleus	NOUN
fnp-5721	56	13	and	and	CCONJ
fnp-5721	56	14	their	their	PRON
fnp-5721	56	15	immunohistochemical	immunohistochemical	ADJ
fnp-5721	56	16	profile	profile	NOUN
fnp-5721	56	17	do	do	AUX
fnp-5721	56	18	not	not	PART
fnp-5721	56	19	match	match	VERB
fnp-5721	56	20	to	to	ADP
fnp-5721	56	21	any	any	DET
fnp-5721	56	22	specific	specific	ADJ
fnp-5721	56	23	neurodegenerative	neurodegenerative	ADJ
fnp-5721	56	24	condition	condition	NOUN
fnp-5721	56	25	but	but	CCONJ
fnp-5721	56	26	may	may	AUX
fnp-5721	56	27	be	be	AUX
fnp-5721	56	28	associated	associate	VERB
fnp-5721	56	29	with	with	ADP
fnp-5721	56	30	subtle	subtle	ADJ
fnp-5721	56	31	and	and	CCONJ
fnp-5721	56	32	slowly	slowly	ADV
fnp-5721	56	33	progressing	progress	VERB
fnp-5721	56	34	neurological	neurological	ADJ
fnp-5721	56	35	symptoms	symptom	NOUN
fnp-5721	56	36	such	such	ADJ
fnp-5721	56	37	as	as	ADP
fnp-5721	56	38	rbd	rbd	NOUN
fnp-5721	56	39	or	or	CCONJ
fnp-5721	56	40	reduced	reduce	VERB
fnp-5721	56	41	cognitive	cognitive	ADJ
fnp-5721	56	42	flexibility	flexibility	NOUN
fnp-5721	56	43	.	.	PUNCT
fnp-5721	57	1	declarations	declaration	NOUN
fnp-5721	57	2	conflicts	conflict	NOUN
fnp-5721	57	3	of	of	ADP
fnp-5721	57	4	interest	interest	NOUN
fnp-5721	57	5	statement	statement	NOUN
fnp-5721	57	6	the	the	DET
fnp-5721	57	7	authors	author	NOUN
fnp-5721	57	8	declare	declare	VERB
fnp-5721	57	9	that	that	SCONJ
fnp-5721	57	10	they	they	PRON
fnp-5721	57	11	have	have	VERB
fnp-5721	57	12	no	no	DET
fnp-5721	57	13	conflicts	conflict	NOUN
fnp-5721	57	14	of	of	ADP
fnp-5721	57	15	interest	interest	NOUN
fnp-5721	57	16	directly	directly	ADV
fnp-5721	57	17	related	relate	VERB
fnp-5721	57	18	to	to	ADP
fnp-5721	57	19	the	the	DET
fnp-5721	57	20	topic	topic	NOUN
fnp-5721	57	21	of	of	ADP
fnp-5721	57	22	this	this	DET
fnp-5721	57	23	article	article	NOUN
fnp-5721	57	24	.	.	PUNCT
fnp-5721	58	1	funding	funding	NOUN
fnp-5721	58	2	statement	statement	NOUN
fnp-5721	58	3	the	the	DET
fnp-5721	58	4	authors	author	NOUN
fnp-5721	58	5	declare	declare	VERB
fnp-5721	58	6	that	that	SCONJ
fnp-5721	58	7	they	they	PRON
fnp-5721	58	8	have	have	AUX
fnp-5721	58	9	not	not	PART
fnp-5721	58	10	received	receive	VERB
fnp-5721	58	11	any	any	DET
fnp-5721	58	12	specific	specific	ADJ
fnp-5721	58	13	funding	funding	NOUN
fnp-5721	58	14	for	for	ADP
fnp-5721	58	15	this	this	DET
fnp-5721	58	16	study	study	NOUN
fnp-5721	58	17	.	.	PUNCT
fnp-5721	59	1	the	the	DET
fnp-5721	59	2	austrian	austrian	ADJ
fnp-5721	59	3	reference	reference	NOUN
fnp-5721	59	4	center	center	NOUN
fnp-5721	59	5	for	for	ADP
fnp-5721	59	6	human	human	ADJ
fnp-5721	59	7	prion	prion	NOUN
fnp-5721	59	8	disease	disease	NOUN
fnp-5721	59	9	(	(	PUNCT
fnp-5721	59	10	örpe	örpe	NOUN
fnp-5721	59	11	)	)	PUNCT
fnp-5721	59	12	is	be	AUX
fnp-5721	59	13	supported	support	VERB
fnp-5721	59	14	by	by	ADP
fnp-5721	59	15	the	the	DET
fnp-5721	59	16	austrian	austrian	PROPN
fnp-5721	59	17	ministry	ministry	PROPN
fnp-5721	59	18	of	of	ADP
fnp-5721	59	19	health	health	PROPN
fnp-5721	59	20	(	(	PUNCT
fnp-5721	59	21	federal	federal	PROPN
fnp-5721	59	22	ministry	ministry	PROPN
fnp-5721	59	23	republic	republic	PROPN
fnp-5721	59	24	of	of	ADP
fnp-5721	59	25	austria	austria	PROPN
fnp-5721	59	26	for	for	ADP
fnp-5721	59	27	social	social	ADJ
fnp-5721	59	28	affairs	affair	NOUN
fnp-5721	59	29	,	,	PUNCT
fnp-5721	59	30	health	health	NOUN
fnp-5721	59	31	,	,	PUNCT
fnp-5721	59	32	care	care	NOUN
fnp-5721	59	33	and	and	CCONJ
fnp-5721	59	34	consumer	consumer	NOUN
fnp-5721	59	35	protection	protection	NOUN
fnp-5721	59	36	)	)	PUNCT
fnp-5721	59	37	.	.	PUNCT
fnp-5721	60	1	author	author	NOUN
fnp-5721	60	2	contributions	contribution	NOUN
fnp-5721	60	3	ok	ok	ADV
fnp-5721	60	4	and	and	CCONJ
fnp-5721	60	5	sw	sw	PROPN
fnp-5721	60	6	performed	perform	VERB
fnp-5721	60	7	the	the	DET
fnp-5721	60	8	autopsy	autopsy	NOUN
fnp-5721	60	9	;	;	PUNCT
fnp-5721	60	10	fl	fl	X
fnp-5721	60	11	,	,	PUNCT
fnp-5721	60	12	ok	ok	INTJ
fnp-5721	60	13	,	,	PUNCT
fnp-5721	60	14	sw	sw	PROPN
fnp-5721	60	15	and	and	CCONJ
fnp-5721	60	16	eg	eg	NOUN
fnp-5721	60	17	conducted	conduct	VERB
fnp-5721	60	18	the	the	DET
fnp-5721	60	19	neuropathological	neuropathological	ADJ
fnp-5721	60	20	studies	study	NOUN
fnp-5721	60	21	;	;	PUNCT
fnp-5721	60	22	sk	sk	PROPN
fnp-5721	60	23	and	and	CCONJ
fnp-5721	60	24	cs	cs	PROPN
fnp-5721	60	25	collected	collect	VERB
fnp-5721	60	26	the	the	DET
fnp-5721	60	27	clinical	clinical	ADJ
fnp-5721	60	28	information	information	NOUN
fnp-5721	60	29	,	,	PUNCT
fnp-5721	60	30	mri	mri	NOUN
fnp-5721	60	31	and	and	CCONJ
fnp-5721	60	32	csf	csf	ADJ
fnp-5721	60	33	data	datum	NOUN
fnp-5721	60	34	;	;	PUNCT
fnp-5721	60	35	fl	fl	NUM
fnp-5721	60	36	and	and	CCONJ
fnp-5721	60	37	eg	eg	NOUN
fnp-5721	60	38	drafted	draft	VERB
fnp-5721	60	39	the	the	DET
fnp-5721	60	40	manuscript	manuscript	NOUN
fnp-5721	60	41	.	.	PUNCT
fnp-5721	61	1	all	all	DET
fnp-5721	61	2	authors	author	NOUN
fnp-5721	61	3	reviewed	review	VERB
fnp-5721	61	4	the	the	DET
fnp-5721	61	5	manuscript	manuscript	NOUN
fnp-5721	61	6	.	.	PUNCT
fnp-5721	62	1	acknowledgements	acknowledgement	NOUN
fnp-5721	62	2	we	we	PRON
fnp-5721	62	3	would	would	AUX
fnp-5721	62	4	like	like	VERB
fnp-5721	62	5	to	to	PART
fnp-5721	62	6	thank	thank	VERB
fnp-5721	62	7	the	the	DET
fnp-5721	62	8	laboratory	laboratory	NOUN
fnp-5721	62	9	technicians	technician	NOUN
fnp-5721	62	10	at	at	ADP
fnp-5721	62	11	the	the	DET
fnp-5721	62	12	division	division	NOUN
fnp-5721	62	13	of	of	ADP
fnp-5721	62	14	neuropathology	neuropathology	NOUN
fnp-5721	62	15	and	and	CCONJ
fnp-5721	62	16	neurochemistry	neurochemistry	NOUN
fnp-5721	62	17	,	,	PUNCT
fnp-5721	62	18	medical	medical	ADJ
fnp-5721	62	19	university	university	NOUN
fnp-5721	62	20	vienna	vienna	NOUN
fnp-5721	62	21	for	for	ADP
fnp-5721	62	22	their	their	PRON
fnp-5721	62	23	assistance	assistance	NOUN
fnp-5721	62	24	.	.	PUNCT
fnp-5721	63	1	we	we	PRON
fnp-5721	63	2	deeply	deeply	ADV
fnp-5721	63	3	thank	thank	VERB
fnp-5721	63	4	patients	patient	NOUN
fnp-5721	63	5	and	and	CCONJ
fnp-5721	63	6	their	their	PRON
fnp-5721	63	7	families	family	NOUN
fnp-5721	63	8	.	.	PUNCT
fnp-5721	64	1	references	reference	NOUN
fnp-5721	64	2	1	1	NUM
fnp-5721	64	3	.	.	PUNCT
fnp-5721	64	4	hainfellner	hainfellner	NOUN
fnp-5721	64	5	,	,	PUNCT
fnp-5721	64	6	j.	j.	PROPN
fnp-5721	64	7	a.	a.	PROPN
fnp-5721	64	8	et	et	PROPN
fnp-5721	64	9	al	al	PROPN
fnp-5721	64	10	.	.	PROPN
fnp-5721	64	11	coexistence	coexistence	PROPN
fnp-5721	64	12	of	of	ADP
fnp-5721	64	13	alzheimer	alzheimer	NOUN
fnp-5721	64	14	-	-	PUNCT
fnp-5721	64	15	type	type	NOUN
fnp-5721	64	16	neuropathology	neuropathology	NOUN
fnp-5721	64	17	in	in	ADP
fnp-5721	64	18	creutzfeldt	creutzfeldt	ADJ
fnp-5721	64	19	-	-	PUNCT
fnp-5721	64	20	jakob	jakob	ADJ
fnp-5721	64	21	disease	disease	NOUN
fnp-5721	64	22	.	.	PUNCT
fnp-5721	65	1	acta	acta	PROPN
fnp-5721	65	2	neuropathol	neuropathol	PROPN
fnp-5721	65	3	96	96	NUM
fnp-5721	65	4	,	,	PUNCT
fnp-5721	65	5	116–122	116–122	NUM
fnp-5721	65	6	(	(	PUNCT
fnp-5721	65	7	1998	1998	NUM
fnp-5721	65	8	)	)	PUNCT
fnp-5721	65	9	.	.	PUNCT
fnp-5721	66	1	doi	doi	NOUN
fnp-5721	66	2	:	:	PUNCT
fnp-5721	66	3	https://doi.org/10.1007/s004010050870	https://doi.org/10.1007/s004010050870	PROPN
fnp-5721	66	4	2	2	NUM
fnp-5721	66	5	.	.	PUNCT
fnp-5721	66	6	tousseyn	tousseyn	VERB
fnp-5721	66	7	,	,	PUNCT
fnp-5721	66	8	t.	t.	PROPN
fnp-5721	66	9	a.	a.	NOUN
fnp-5721	66	10	et	et	PROPN
fnp-5721	66	11	al	al	PROPN
fnp-5721	66	12	.	.	PROPN
fnp-5721	66	13	coexistence	coexistence	PROPN
fnp-5721	66	14	of	of	ADP
fnp-5721	66	15	alzheimer	alzheimer	NOUN
fnp-5721	66	16	-	-	PUNCT
fnp-5721	66	17	type	type	NOUN
fnp-5721	66	18	neuropathology	neuropathology	NOUN
fnp-5721	66	19	in	in	ADP
fnp-5721	66	20	creutzfeldt	creutzfeldt	ADJ
fnp-5721	66	21	-	-	PUNCT
fnp-5721	66	22	jakob	jakob	ADJ
fnp-5721	66	23	disease	disease	NOUN
fnp-5721	66	24	.	.	PUNCT
fnp-5721	67	1	alzheimer	alzheimer	PROPN
fnp-5721	67	2	’s	’s	PART
fnp-5721	67	3	&	&	CCONJ
fnp-5721	67	4	dementia	dementia	PROPN
fnp-5721	67	5	4	4	NUM
fnp-5721	67	6	,	,	PUNCT
fnp-5721	67	7	t432	t432	PROPN
fnp-5721	67	8	–	–	PUNCT
fnp-5721	67	9	t433	t433	PROPN
fnp-5721	67	10	(	(	PUNCT
fnp-5721	67	11	2008	2008	NUM
fnp-5721	67	12	)	)	PUNCT
fnp-5721	67	13	.	.	PUNCT
fnp-5721	68	1	doi	doi	NOUN
fnp-5721	68	2	:	:	PUNCT
fnp-5721	68	3	https://doi.org/10.1016/j.jalz.2008.05.1285	https://doi.org/10.1016/j.jalz.2008.05.1285	NOUN
fnp-5721	68	4	3	3	X
fnp-5721	68	5	.	.	PUNCT
fnp-5721	68	6	grau	grau	NOUN
fnp-5721	68	7	-	-	PUNCT
fnp-5721	68	8	rivera	rivera	PROPN
fnp-5721	68	9	,	,	PUNCT
fnp-5721	68	10	o.	o.	NOUN
fnp-5721	68	11	et	et	PROPN
fnp-5721	68	12	al	al	PROPN
fnp-5721	68	13	.	.	PROPN
fnp-5721	69	1	clinicopathological	clinicopathological	ADJ
fnp-5721	69	2	correlations	correlation	NOUN
fnp-5721	69	3	and	and	CCONJ
fnp-5721	69	4	concomitant	concomitant	ADJ
fnp-5721	69	5	pathologies	pathology	NOUN
fnp-5721	69	6	in	in	ADP
fnp-5721	69	7	rapidly	rapidly	ADV
fnp-5721	69	8	progressive	progressive	ADJ
fnp-5721	69	9	dementia	dementia	NOUN
fnp-5721	69	10	:	:	PUNCT
fnp-5721	69	11	a	a	DET
fnp-5721	69	12	brain	brain	NOUN
fnp-5721	69	13	bank	bank	NOUN
fnp-5721	69	14	series	series	NOUN
fnp-5721	69	15	.	.	PUNCT
fnp-5721	70	1	neurodegenerative	neurodegenerative	ADJ
fnp-5721	70	2	diseases	disease	NOUN
fnp-5721	70	3	15	15	NUM
fnp-5721	70	4	,	,	PUNCT
fnp-5721	70	5	350–360	350–360	NUM
fnp-5721	70	6	(	(	PUNCT
fnp-5721	70	7	2015	2015	NUM
fnp-5721	70	8	)	)	PUNCT
fnp-5721	70	9	.	.	PUNCT
fnp-5721	71	1	doi	doi	NOUN
fnp-5721	71	2	:	:	PUNCT
fnp-5721	71	3	https://doi.org/10.1159/000439251	https://doi.org/10.1159/000439251	NOUN
fnp-5721	71	4	4	4	NUM
fnp-5721	71	5	.	.	X
fnp-5721	71	6	iida	iida	PROPN
fnp-5721	71	7	,	,	PUNCT
fnp-5721	71	8	t.	t.	PROPN
fnp-5721	71	9	et	et	PROPN
fnp-5721	71	10	al	al	PROPN
fnp-5721	71	11	.	.	PUNCT
fnp-5721	72	1	an	an	DET
fnp-5721	72	2	atypical	atypical	ADJ
fnp-5721	72	3	case	case	NOUN
fnp-5721	72	4	of	of	ADP
fnp-5721	72	5	sporadic	sporadic	ADJ
fnp-5721	72	6	creutzfeldt	creutzfeldt	ADJ
fnp-5721	72	7	-	-	PUNCT
fnp-5721	72	8	jakob	jakob	ADJ
fnp-5721	72	9	disease	disease	NOUN
fnp-5721	72	10	with	with	ADP
fnp-5721	72	11	parkinson	parkinson	NOUN
fnp-5721	72	12	’s	’s	PART
fnp-5721	72	13	disease	disease	NOUN
fnp-5721	72	14	.	.	PUNCT
fnp-5721	73	1	neuropathology	neuropathology	NOUN
fnp-5721	73	2	21	21	NUM
fnp-5721	73	3	,	,	PUNCT
fnp-5721	73	4	294–297	294–297	NUM
fnp-5721	73	5	(	(	PUNCT
fnp-5721	73	6	2001	2001	NUM
fnp-5721	73	7	)	)	PUNCT
fnp-5721	73	8	.	.	PUNCT
fnp-5721	74	1	doi	doi	NOUN
fnp-5721	74	2	:	:	PUNCT
fnp-5721	74	3	https://doi.org/10.1046/j.1440-1789.2001.00407.x	https://doi.org/10.1046/j.1440-1789.2001.00407.x	PROPN
fnp-5721	74	4	5	5	X
fnp-5721	74	5	.	.	PUNCT
fnp-5721	74	6	haraguchi	haraguchi	NOUN
fnp-5721	74	7	,	,	PUNCT
fnp-5721	75	1	t.	t.	PROPN
fnp-5721	75	2	et	et	PROPN
fnp-5721	75	3	al	al	PROPN
fnp-5721	75	4	.	.	PUNCT
fnp-5721	75	5	coexistence	coexistence	NOUN
fnp-5721	75	6	of	of	ADP
fnp-5721	75	7	creutzfeldt	creutzfeldt	ADJ
fnp-5721	75	8	-	-	ADJ
fnp-5721	75	9	jakob	jakob	ADJ
fnp-5721	75	10	disease	disease	PROPN
fnp-5721	75	11	,	,	PUNCT
fnp-5721	75	12	lewy	lewy	PROPN
fnp-5721	75	13	body	body	NOUN
fnp-5721	75	14	disease	disease	NOUN
fnp-5721	75	15	,	,	PUNCT
fnp-5721	75	16	and	and	CCONJ
fnp-5721	75	17	alzheimer	alzheimer	PROPN
fnp-5721	75	18	’s	’s	PART
fnp-5721	75	19	disease	disease	NOUN
fnp-5721	75	20	pathology	pathology	NOUN
fnp-5721	75	21	:	:	PUNCT
fnp-5721	75	22	an	an	DET
fnp-5721	75	23	autopsy	autopsy	ADJ
fnp-5721	75	24	case	case	NOUN
fnp-5721	75	25	showing	show	VERB
fnp-5721	75	26	typical	typical	ADJ
fnp-5721	75	27	clinical	clinical	ADJ
fnp-5721	75	28	features	feature	NOUN
fnp-5721	75	29	of	of	ADP
fnp-5721	75	30	creutzfeldt	creutzfeldt	ADJ
fnp-5721	75	31	-	-	ADJ
fnp-5721	75	32	jakob	jakob	ADJ
fnp-5721	75	33	disease	disease	NOUN
fnp-5721	75	34	.	.	PUNCT
fnp-5721	76	1	neuropathology	neuropathology	NOUN
fnp-5721	76	2	29	29	NUM
fnp-5721	76	3	,	,	PUNCT
fnp-5721	76	4	454–459	454–459	NUM
fnp-5721	76	5	(	(	PUNCT
fnp-5721	76	6	2009	2009	NUM
fnp-5721	76	7	)	)	PUNCT
fnp-5721	76	8	.	.	PUNCT
fnp-5721	77	1	doi	doi	NOUN
fnp-5721	77	2	:	:	PUNCT
fnp-5721	77	3	https://doi.org/10.1111/j.1440-1789.2008.00964.x	https://doi.org/10.1111/j.1440-1789.2008.00964.x	NUM
fnp-5721	77	4	6	6	NUM
fnp-5721	77	5	.	.	PUNCT
fnp-5721	78	1	fernández	fernández	PROPN
fnp-5721	78	2	-	-	PUNCT
fnp-5721	78	3	vega	vega	PROPN
fnp-5721	78	4	,	,	PUNCT
fnp-5721	78	5	i.	i.	PROPN
fnp-5721	78	6	et	et	PROPN
fnp-5721	78	7	al	al	PROPN
fnp-5721	78	8	.	.	PROPN
fnp-5721	78	9	coexistence	coexistence	NOUN
fnp-5721	78	10	of	of	ADP
fnp-5721	78	11	mixed	mixed	ADJ
fnp-5721	78	12	phenotype	phenotype	NOUN
fnp-5721	78	13	creutzfeldt	creutzfeldt	ADJ
fnp-5721	78	14	-	-	PUNCT
fnp-5721	78	15	jakob	jakob	ADJ
fnp-5721	78	16	disease	disease	PROPN
fnp-5721	78	17	,	,	PUNCT
fnp-5721	78	18	lewy	lewy	PROPN
fnp-5721	78	19	body	body	NOUN
fnp-5721	78	20	disease	disease	NOUN
fnp-5721	78	21	and	and	CCONJ
fnp-5721	78	22	argyrophilic	argyrophilic	ADJ
fnp-5721	78	23	grain	grain	NOUN
fnp-5721	78	24	disease	disease	NOUN
fnp-5721	78	25	plus	plus	CCONJ
fnp-5721	78	26	histological	histological	ADJ
fnp-5721	78	27	features	feature	NOUN
fnp-5721	78	28	of	of	ADP
fnp-5721	78	29	possible	possible	ADJ
fnp-5721	78	30	alzheimer	alzheimer	PROPN
fnp-5721	78	31	’s	’s	PART
fnp-5721	78	32	disease	disease	NOUN
fnp-5721	78	33	:	:	PUNCT
fnp-5721	78	34	a	a	DET
fnp-5721	78	35	multi	multi	ADJ
fnp-5721	78	36	-	-	ADJ
fnp-5721	78	37	protein	protein	ADJ
fnp-5721	78	38	disorder	disorder	NOUN
fnp-5721	78	39	in	in	ADP
fnp-5721	78	40	an	an	DET
fnp-5721	78	41	autopsy	autopsy	ADJ
fnp-5721	78	42	case	case	NOUN
fnp-5721	78	43	.	.	PUNCT
fnp-5721	79	1	neuropathology	neuropathology	NOUN
fnp-5721	79	2	35	35	NUM
fnp-5721	79	3	,	,	PUNCT
fnp-5721	79	4	56–63	56–63	NUM
fnp-5721	79	5	(	(	PUNCT
fnp-5721	79	6	2015	2015	NUM
fnp-5721	79	7	)	)	PUNCT
fnp-5721	79	8	.	.	PUNCT
fnp-5721	80	1	doi	doi	NOUN
fnp-5721	80	2	:	:	PUNCT
fnp-5721	80	3	https://doi.org/10.1111/neup.12150	https://doi.org/10.1111/neup.12150	PROPN
fnp-5721	80	4	7	7	NUM
fnp-5721	80	5	.	.	PUNCT
fnp-5721	80	6	rossi	rossi	PROPN
fnp-5721	80	7	,	,	PUNCT
fnp-5721	80	8	m.	m.	NOUN
fnp-5721	80	9	et	et	PROPN
fnp-5721	80	10	al	al	PROPN
fnp-5721	80	11	.	.	PUNCT
fnp-5721	81	1	the	the	DET
fnp-5721	81	2	characterization	characterization	NOUN
fnp-5721	81	3	of	of	ADP
fnp-5721	81	4	ad	ad	NOUN
fnp-5721	81	5	/	/	SYM
fnp-5721	81	6	part	part	NOUN
fnp-5721	81	7	co	co	NOUN
fnp-5721	81	8	-	-	NOUN
fnp-5721	81	9	pathology	pathology	NOUN
fnp-5721	81	10	in	in	ADP
fnp-5721	81	11	cjd	cjd	PROPN
fnp-5721	81	12	suggests	suggest	VERB
fnp-5721	81	13	independent	independent	ADJ
fnp-5721	81	14	pathogenic	pathogenic	ADJ
fnp-5721	81	15	mechanisms	mechanism	NOUN
fnp-5721	81	16	and	and	CCONJ
fnp-5721	81	17	no	no	DET
fnp-5721	81	18	cross	cross	ADJ
fnp-5721	81	19	-	-	ADJ
fnp-5721	81	20	seeding	seed	VERB
fnp-5721	81	21	between	between	ADP
fnp-5721	81	22	misfolded	misfolde	VERB
fnp-5721	81	23	aβ	aβ	NOUN
fnp-5721	81	24	and	and	CCONJ
fnp-5721	81	25	prion	prion	NOUN
fnp-5721	81	26	proteins	protein	NOUN
fnp-5721	81	27	.	.	PUNCT
fnp-5721	82	1	acta	acta	PROPN
fnp-5721	82	2	neuropathol	neuropathol	PROPN
fnp-5721	82	3	commun	commun	PROPN
fnp-5721	82	4	7	7	NUM
fnp-5721	82	5	,	,	PUNCT
fnp-5721	82	6	53	53	NUM
fnp-5721	82	7	(	(	PUNCT
fnp-5721	82	8	2019	2019	NUM
fnp-5721	82	9	)	)	PUNCT
fnp-5721	82	10	.	.	PUNCT
fnp-5721	83	1	doi	doi	NOUN
fnp-5721	83	2	:	:	PUNCT
fnp-5721	83	3	https://doi.org/10.1186/s40478-019-0706-6	https://doi.org/10.1186/s40478-019-0706-6	NUM
fnp-5721	83	4	8	8	NUM
fnp-5721	83	5	.	.	PUNCT
fnp-5721	84	1	kovacs	kovacs	PROPN
fnp-5721	84	2	,	,	PUNCT
fnp-5721	84	3	g.	g.	PROPN
fnp-5721	84	4	g.	g.	PROPN
fnp-5721	84	5	et	et	PROPN
fnp-5721	85	1	al	al	PROPN
fnp-5721	85	2	.	.	PUNCT
fnp-5721	85	3	non	non	ADJ
fnp-5721	85	4	-	-	ADJ
fnp-5721	85	5	alzheimer	alzheimer	ADJ
fnp-5721	85	6	neurodegenerative	neurodegenerative	ADJ
fnp-5721	85	7	pathologies	pathology	NOUN
fnp-5721	85	8	and	and	CCONJ
fnp-5721	85	9	their	their	PRON
fnp-5721	85	10	combinations	combination	NOUN
fnp-5721	85	11	are	be	AUX
fnp-5721	85	12	more	more	ADV
fnp-5721	85	13	frequent	frequent	ADJ
fnp-5721	85	14	than	than	SCONJ
fnp-5721	85	15	commonly	commonly	ADV
fnp-5721	85	16	believed	believe	VERB
fnp-5721	85	17	in	in	ADP
fnp-5721	85	18	the	the	DET
fnp-5721	85	19	elderly	elderly	ADJ
fnp-5721	85	20	brain	brain	NOUN
fnp-5721	85	21	:	:	PUNCT
fnp-5721	85	22	a	a	DET
fnp-5721	85	23	community	community	NOUN
fnp-5721	85	24	-	-	PUNCT
fnp-5721	85	25	based	base	VERB
fnp-5721	85	26	autopsy	autopsy	ADJ
fnp-5721	85	27	series	series	NOUN
fnp-5721	85	28	.	.	PUNCT
fnp-5721	86	1	acta	acta	PROPN
fnp-5721	86	2	neuropathol	neuropathol	PROPN
fnp-5721	86	3	126	126	NUM
fnp-5721	86	4	,	,	PUNCT
fnp-5721	86	5	365–384	365–384	NUM
fnp-5721	86	6	(	(	PUNCT
fnp-5721	86	7	2013	2013	NUM
fnp-5721	86	8	)	)	PUNCT
fnp-5721	86	9	.	.	PUNCT
fnp-5721	87	1	doi	doi	NOUN
fnp-5721	87	2	:	:	PUNCT
fnp-5721	87	3	https://doi.org/10.1007/s00401-013-1157-y	https://doi.org/10.1007/s00401-013-1157-y	NOUN
fnp-5721	87	4	9	9	NUM
fnp-5721	87	5	.	.	PUNCT
fnp-5721	88	1	diagnostic	diagnostic	ADJ
fnp-5721	88	2	criteria	criterion	NOUN
fnp-5721	88	3	|	|	CCONJ
fnp-5721	88	4	creutzfeldt	creutzfeldt	ADJ
fnp-5721	88	5	-	-	PUNCT
fnp-5721	88	6	jakob	jakob	ADJ
fnp-5721	88	7	disease	disease	NOUN
fnp-5721	88	8	,	,	PUNCT
fnp-5721	88	9	classic	classic	ADJ
fnp-5721	88	10	(	(	PUNCT
fnp-5721	88	11	cjd	cjd	NOUN
fnp-5721	88	12	)	)	PUNCT
fnp-5721	88	13	|	|	ADV
fnp-5721	88	14	prion	prion	NOUN
fnp-5721	88	15	disease	disease	NOUN
fnp-5721	88	16	|	|	PROPN
fnp-5721	88	17	cdc	cdc	PROPN
fnp-5721	88	18	.	.	PUNCT
fnp-5721	89	1	(	(	PUNCT
fnp-5721	89	2	2021	2021	NUM
fnp-5721	89	3	)	)	PUNCT
fnp-5721	89	4	.	.	PUNCT
fnp-5721	90	1	https://www.cdc.gov/prions/cjd/diagnostic-criteria.html	https://www.cdc.gov/prions/cjd/diagnostic-criteria.html	PROPN
fnp-5721	90	2	10	10	NUM
fnp-5721	90	3	.	.	PUNCT
fnp-5721	91	1	iwasaki	iwasaki	PROPN
fnp-5721	91	2	,	,	PUNCT
fnp-5721	91	3	y.	y.	PROPN
fnp-5721	91	4	the	the	DET
fnp-5721	91	5	braak	braak	PROPN
fnp-5721	91	6	hypothesis	hypothesis	NOUN
fnp-5721	91	7	in	in	ADP
fnp-5721	91	8	prion	prion	NOUN
fnp-5721	91	9	disease	disease	NOUN
fnp-5721	91	10	with	with	ADP
fnp-5721	91	11	a	a	DET
fnp-5721	91	12	focus	focus	NOUN
fnp-5721	91	13	on	on	ADP
fnp-5721	91	14	creutzfeldt	creutzfeldt	ADJ
fnp-5721	91	15	–	–	PUNCT
fnp-5721	91	16	jakob	jakob	PROPN
fnp-5721	91	17	disease	disease	NOUN
fnp-5721	91	18	.	.	PUNCT
fnp-5721	92	1	neuropathology	neuropathology	NOUN
fnp-5721	92	2	40	40	NUM
fnp-5721	92	3	,	,	PUNCT
fnp-5721	92	4	436–449	436–449	NUM
fnp-5721	92	5	(	(	PUNCT
fnp-5721	92	6	2020	2020	NUM
fnp-5721	92	7	)	)	PUNCT
fnp-5721	92	8	.	.	PUNCT
fnp-5721	93	1	doi	doi	NOUN
fnp-5721	93	2	:	:	PUNCT
fnp-5721	93	3	https://doi.org/10.1111/neup.12654	https://doi.org/10.1111/neup.12654	ADJ
fnp-5721	93	4	11	11	NUM
fnp-5721	93	5	.	.	PUNCT
fnp-5721	94	1	parchi	parchi	NOUN
fnp-5721	94	2	,	,	PUNCT
fnp-5721	94	3	p.	p.	NOUN
fnp-5721	94	4	et	et	NOUN
fnp-5721	95	1	al	al	PROPN
fnp-5721	95	2	.	.	PUNCT
fnp-5721	96	1	classification	classification	NOUN
fnp-5721	96	2	of	of	ADP
fnp-5721	96	3	sporadic	sporadic	ADJ
fnp-5721	96	4	creutzfeldt	creutzfeldt	ADJ
fnp-5721	96	5	-	-	PUNCT
fnp-5721	96	6	jakob	jakob	ADJ
fnp-5721	96	7	disease	disease	NOUN
fnp-5721	96	8	based	base	VERB
fnp-5721	96	9	on	on	ADP
fnp-5721	96	10	molecular	molecular	ADJ
fnp-5721	96	11	and	and	CCONJ
fnp-5721	96	12	phenotypic	phenotypic	ADJ
fnp-5721	96	13	analysis	analysis	NOUN
fnp-5721	96	14	of	of	ADP
fnp-5721	96	15	300	300	NUM
fnp-5721	96	16	subjects	subject	NOUN
fnp-5721	96	17	.	.	PUNCT
fnp-5721	97	1	annals	annal	NOUN
fnp-5721	97	2	of	of	ADP
fnp-5721	97	3	neurology	neurology	NOUN
fnp-5721	97	4	46	46	NUM
fnp-5721	97	5	,	,	PUNCT
fnp-5721	97	6	224–233	224–233	NUM
fnp-5721	97	7	(	(	PUNCT
fnp-5721	97	8	1999	1999	NUM
fnp-5721	97	9	)	)	PUNCT
fnp-5721	97	10	.	.	PUNCT
fnp-5721	98	1	doi	doi	NOUN
fnp-5721	98	2	:	:	PUNCT
fnp-5721	98	3	https://doi.org/10.1002/1531-8249(199908)46:23.0.co;2-w	https://doi.org/10.1002/1531-8249(199908)46:23.0.co;2-w	PROPN
fnp-5721	98	4	12	12	NUM
fnp-5721	98	5	.	.	PUNCT
fnp-5721	99	1	benarroch	benarroch	PROPN
fnp-5721	99	2	,	,	PUNCT
fnp-5721	99	3	e.	e.	PROPN
fnp-5721	99	4	e.	e.	PROPN
fnp-5721	99	5	locus	locus	PROPN
fnp-5721	99	6	coeruleus	coeruleus	NOUN
fnp-5721	99	7	.	.	PUNCT
fnp-5721	100	1	cell	cell	NOUN
fnp-5721	100	2	tissue	tissue	NOUN
fnp-5721	100	3	res	re	NOUN
fnp-5721	100	4	373	373	NUM
fnp-5721	100	5	,	,	PUNCT
fnp-5721	100	6	221–232	221–232	NUM
fnp-5721	100	7	(	(	PUNCT
fnp-5721	100	8	2018	2018	NUM
fnp-5721	100	9	)	)	PUNCT
fnp-5721	100	10	.	.	PUNCT
fnp-5721	101	1	doi	doi	NOUN
fnp-5721	101	2	:	:	PUNCT
fnp-5721	101	3	https://doi.org/10.1007/s00441-017-2649-1	https://doi.org/10.1007/s00441-017-2649-1	PROPN
fnp-5721	101	4	13	13	NUM
fnp-5721	101	5	.	.	PUNCT
fnp-5721	101	6	zucca	zucca	PROPN
fnp-5721	101	7	,	,	PUNCT
fnp-5721	101	8	f.	f.	PROPN
fnp-5721	101	9	a.	a.	PROPN
fnp-5721	101	10	et	et	PROPN
fnp-5721	101	11	al	al	PROPN
fnp-5721	101	12	.	.	PUNCT
fnp-5721	102	1	interactions	interaction	NOUN
fnp-5721	102	2	of	of	ADP
fnp-5721	102	3	iron	iron	NOUN
fnp-5721	102	4	,	,	PUNCT
fnp-5721	102	5	dopamine	dopamine	NOUN
fnp-5721	102	6	and	and	CCONJ
fnp-5721	102	7	neuromelanin	neuromelanin	ADJ
fnp-5721	102	8	pathways	pathway	NOUN
fnp-5721	102	9	in	in	ADP
fnp-5721	102	10	brain	brain	NOUN
fnp-5721	102	11	aging	aging	NOUN
fnp-5721	102	12	and	and	CCONJ
fnp-5721	102	13	parkinson	parkinson	NOUN
fnp-5721	102	14	’s	’s	PART
fnp-5721	102	15	disease	disease	NOUN
fnp-5721	102	16	.	.	PUNCT
fnp-5721	103	1	prog	prog	PROPN
fnp-5721	103	2	neurobiol	neurobiol	PROPN
fnp-5721	103	3	155	155	NUM
fnp-5721	103	4	,	,	PUNCT
fnp-5721	103	5	96–119	96–119	NUM
fnp-5721	103	6	(	(	PUNCT
fnp-5721	103	7	2017	2017	NUM
fnp-5721	103	8	)	)	PUNCT
fnp-5721	103	9	.	.	PUNCT
fnp-5721	104	1	doi	doi	NOUN
fnp-5721	104	2	:	:	PUNCT
fnp-5721	104	3	https://doi.org/10.1016/j.pneurobio.2015.09.012	https://doi.org/10.1016/j.pneurobio.2015.09.012	PROPN
fnp-5721	104	4	14	14	NUM
fnp-5721	104	5	.	.	PUNCT
fnp-5721	105	1	braak	braak	PROPN
fnp-5721	105	2	,	,	PUNCT
fnp-5721	105	3	h.	h.	PROPN
fnp-5721	105	4	et	et	PROPN
fnp-5721	105	5	al	al	PROPN
fnp-5721	105	6	.	.	PROPN
fnp-5721	105	7	staging	staging	NOUN
fnp-5721	105	8	of	of	ADP
fnp-5721	105	9	brain	brain	NOUN
fnp-5721	105	10	pathology	pathology	NOUN
fnp-5721	105	11	related	relate	VERB
fnp-5721	105	12	to	to	ADP
fnp-5721	105	13	sporadic	sporadic	ADJ
fnp-5721	105	14	parkinson	parkinson	NOUN
fnp-5721	105	15	’s	’s	PART
fnp-5721	105	16	disease	disease	NOUN
fnp-5721	105	17	.	.	PUNCT
fnp-5721	106	1	neurobiology	neurobiology	NOUN
fnp-5721	106	2	of	of	ADP
fnp-5721	106	3	aging	age	VERB
fnp-5721	106	4	24	24	NUM
fnp-5721	106	5	,	,	PUNCT
fnp-5721	106	6	197–211	197–211	NUM
fnp-5721	106	7	(	(	PUNCT
fnp-5721	106	8	2003	2003	NUM
fnp-5721	106	9	)	)	PUNCT
fnp-5721	106	10	.	.	PUNCT
fnp-5721	107	1	doi	doi	PROPN
fnp-5721	107	2	:	:	PUNCT
fnp-5721	107	3	https://doi.org/10.1016/s0197-4580(02)00065-9	https://doi.org/10.1016/s0197-4580(02)00065-9	PROPN
fnp-5721	107	4	15	15	NUM
fnp-5721	107	5	.	.	PUNCT
fnp-5721	108	1	dauvilliers	dauvillier	NOUN
fnp-5721	108	2	,	,	PUNCT
fnp-5721	108	3	y.	y.	PROPN
fnp-5721	108	4	et	et	PROPN
fnp-5721	108	5	al	al	PROPN
fnp-5721	108	6	.	.	PROPN
fnp-5721	109	1	rem	rem	VERB
fnp-5721	109	2	sleep	sleep	NOUN
fnp-5721	109	3	behaviour	behaviour	NOUN
fnp-5721	109	4	disorder	disorder	NOUN
fnp-5721	109	5	.	.	PUNCT
fnp-5721	110	1	nat	nat	PROPN
fnp-5721	110	2	rev	rev	VERB
fnp-5721	110	3	dis	dis	PROPN
fnp-5721	110	4	primers	primer	NOUN
fnp-5721	110	5	4	4	NUM
fnp-5721	110	6	,	,	PUNCT
fnp-5721	110	7	19	19	NUM
fnp-5721	110	8	(	(	PUNCT
fnp-5721	110	9	2018	2018	NUM
fnp-5721	110	10	)	)	PUNCT
fnp-5721	110	11	.	.	PUNCT
fnp-5721	111	1	doi	doi	PROPN
fnp-5721	111	2	:	:	PUNCT
fnp-5721	111	3	https://doi.org/10.1038/s41572-018-0016-5	https://doi.org/10.1038/s41572-018-0016-5	PROPN
fnp-5721	111	4	16	16	NUM
fnp-5721	111	5	.	.	PUNCT
fnp-5721	112	1	boeve	boeve	PROPN
fnp-5721	112	2	,	,	PUNCT
fnp-5721	112	3	b.	b.	PROPN
fnp-5721	112	4	f.	f.	PROPN
fnp-5721	112	5	et	et	PROPN
fnp-5721	112	6	al	al	PROPN
fnp-5721	112	7	.	.	PUNCT
fnp-5721	113	1	insights	insight	NOUN
fnp-5721	113	2	into	into	ADP
fnp-5721	113	3	rem	rem	PUNCT
fnp-5721	113	4	sleep	sleep	NOUN
fnp-5721	113	5	behavior	behavior	NOUN
fnp-5721	113	6	disorder	disorder	NOUN
fnp-5721	113	7	pathophysiology	pathophysiology	NOUN
fnp-5721	113	8	in	in	ADP
fnp-5721	113	9	brainstem	brainstem	NOUN
fnp-5721	113	10	-	-	PUNCT
fnp-5721	113	11	predominant	predominant	ADJ
fnp-5721	113	12	lewy	lewy	ADJ
fnp-5721	113	13	body	body	NOUN
fnp-5721	113	14	disease	disease	NOUN
fnp-5721	113	15	.	.	PUNCT
fnp-5721	114	1	sleep	sleep	NOUN
fnp-5721	114	2	medicine	medicine	NOUN
fnp-5721	114	3	8	8	NUM
fnp-5721	114	4	,	,	PUNCT
fnp-5721	114	5	60–64	60–64	NUM
fnp-5721	114	6	(	(	PUNCT
fnp-5721	114	7	2007	2007	NUM
fnp-5721	114	8	)	)	PUNCT
fnp-5721	114	9	.	.	PUNCT
fnp-5721	115	1	doi	doi	NOUN
fnp-5721	115	2	:	:	PUNCT
fnp-5721	115	3	https://doi.org/10.1016/j.sleep.2006.08.017	https://doi.org/10.1016/j.sleep.2006.08.017	PROPN
fnp-5721	115	4	17	17	NUM
fnp-5721	115	5	.	.	PUNCT
fnp-5721	116	1	arnulf	arnulf	PROPN
fnp-5721	116	2	,	,	PUNCT
fnp-5721	116	3	i.	i.	PROPN
fnp-5721	116	4	rem	rem	PUNCT
fnp-5721	116	5	sleep	sleep	NOUN
fnp-5721	116	6	behavior	behavior	NOUN
fnp-5721	116	7	disorder	disorder	NOUN
fnp-5721	116	8	:	:	PUNCT
fnp-5721	116	9	motor	motor	NOUN
fnp-5721	116	10	manifestations	manifestation	NOUN
fnp-5721	116	11	and	and	CCONJ
fnp-5721	116	12	pathophysiology	pathophysiology	NOUN
fnp-5721	116	13	.	.	PUNCT
fnp-5721	117	1	movement	movement	NOUN
fnp-5721	117	2	disorders	disorder	NOUN
fnp-5721	117	3	27	27	NUM
fnp-5721	117	4	,	,	PUNCT
fnp-5721	117	5	677–689	677–689	NUM
fnp-5721	117	6	(	(	PUNCT
fnp-5721	117	7	2012	2012	NUM
fnp-5721	117	8	)	)	PUNCT
fnp-5721	117	9	.	.	PUNCT
fnp-5721	118	1	doi	doi	NOUN
fnp-5721	118	2	:	:	PUNCT
fnp-5721	118	3	https://doi.org/10.1002/mds.24957	https://doi.org/10.1002/mds.24957	PROPN
fnp-5721	118	4	18	18	NUM
fnp-5721	118	5	.	.	PUNCT
fnp-5721	118	6	iranzo	iranzo	PROPN
fnp-5721	118	7	,	,	PUNCT
fnp-5721	118	8	a.	a.	PROPN
fnp-5721	118	9	et	et	PROPN
fnp-5721	118	10	al	al	PROPN
fnp-5721	118	11	.	.	PROPN
fnp-5721	118	12	neurodegenerative	neurodegenerative	ADJ
fnp-5721	118	13	disorder	disorder	NOUN
fnp-5721	118	14	risk	risk	NOUN
fnp-5721	118	15	in	in	ADP
fnp-5721	118	16	idiopathic	idiopathic	ADJ
fnp-5721	118	17	rem	rem	PUNCT
fnp-5721	118	18	sleep	sleep	NOUN
fnp-5721	118	19	behavior	behavior	NOUN
fnp-5721	118	20	disorder	disorder	NOUN
fnp-5721	118	21	:	:	PUNCT
fnp-5721	118	22	study	study	NOUN
fnp-5721	118	23	in	in	ADP
fnp-5721	118	24	174	174	NUM
fnp-5721	118	25	patients	patient	NOUN
fnp-5721	118	26	.	.	PUNCT
fnp-5721	119	1	plos	plos	PROPN
fnp-5721	119	2	one	one	NUM
fnp-5721	119	3	9	9	NUM
fnp-5721	119	4	,	,	PUNCT
fnp-5721	119	5	e89741	e89741	PROPN
fnp-5721	119	6	(	(	PUNCT
fnp-5721	119	7	2014	2014	NUM
fnp-5721	119	8	)	)	PUNCT
fnp-5721	119	9	.	.	PUNCT
fnp-5721	120	1	doi	doi	PROPN
fnp-5721	120	2	:	:	PUNCT
fnp-5721	120	3	https://doi.org/10.1371/journal.pone.0089741	https://doi.org/10.1371/journal.pone.0089741	VERB
fnp-5721	120	4	19	19	NUM
fnp-5721	120	5	.	.	PUNCT
fnp-5721	121	1	vazey	vazey	PROPN
fnp-5721	121	2	,	,	PUNCT
fnp-5721	121	3	e.	e.	PROPN
fnp-5721	121	4	m.	m.	PROPN
fnp-5721	121	5	&	&	CCONJ
fnp-5721	121	6	aston	aston	PROPN
fnp-5721	121	7	-	-	PUNCT
fnp-5721	121	8	jones	jones	PROPN
fnp-5721	121	9	,	,	PUNCT
fnp-5721	121	10	g.	g.	PROPN
fnp-5721	122	1	the	the	DET
fnp-5721	122	2	emerging	emerge	VERB
fnp-5721	122	3	role	role	NOUN
fnp-5721	122	4	of	of	ADP
fnp-5721	122	5	norepinephrine	norepinephrine	NOUN
fnp-5721	122	6	in	in	ADP
fnp-5721	122	7	cognitive	cognitive	ADJ
fnp-5721	122	8	dysfunctions	dysfunction	NOUN
fnp-5721	122	9	of	of	ADP
fnp-5721	122	10	parkinson	parkinson	NOUN
fnp-5721	122	11	’s	’s	PART
fnp-5721	122	12	disease	disease	NOUN
fnp-5721	122	13	.	.	PUNCT
fnp-5721	123	1	front	front	ADJ
fnp-5721	123	2	behav	behav	PROPN
fnp-5721	123	3	neurosci	neurosci	PROPN
fnp-5721	123	4	6	6	NUM
fnp-5721	123	5	,	,	PUNCT
fnp-5721	123	6	48	48	NUM
fnp-5721	123	7	(	(	PUNCT
fnp-5721	123	8	2012	2012	NUM
fnp-5721	123	9	)	)	PUNCT
fnp-5721	123	10	.	.	PUNCT
fnp-5721	124	1	doi	doi	NOUN
fnp-5721	124	2	:	:	PUNCT
fnp-5721	124	3	https://doi.org/10.3389/fnbeh.2012.00048	https://doi.org/10.3389/fnbeh.2012.00048	PROPN
fnp-5721	124	4	20	20	NUM
fnp-5721	124	5	.	.	PUNCT
fnp-5721	125	1	mirabile	mirabile	PROPN
fnp-5721	125	2	,	,	PUNCT
fnp-5721	125	3	i.	i.	PROPN
fnp-5721	125	4	et	et	PROPN
fnp-5721	125	5	al	al	PROPN
fnp-5721	125	6	.	.	PUNCT
fnp-5721	125	7	identification	identification	NOUN
fnp-5721	125	8	of	of	ADP
fnp-5721	125	9	clinical	clinical	ADJ
fnp-5721	125	10	target	target	NOUN
fnp-5721	125	11	areas	area	NOUN
fnp-5721	125	12	in	in	ADP
fnp-5721	125	13	the	the	DET
fnp-5721	125	14	brainstem	brainstem	NOUN
fnp-5721	125	15	of	of	ADP
fnp-5721	125	16	prion	prion	NOUN
fnp-5721	125	17	-	-	PUNCT
fnp-5721	125	18	infected	infect	VERB
fnp-5721	125	19	mice	mouse	NOUN
fnp-5721	125	20	.	.	PUNCT
fnp-5721	126	1	neuropathol	neuropathol	NOUN
fnp-5721	126	2	.	.	PUNCT
fnp-5721	127	1	appl	appl	PROPN
fnp-5721	127	2	.	.	PUNCT
fnp-5721	128	1	neurobiol	neurobiol	PROPN
fnp-5721	128	2	.	.	PUNCT
fnp-5721	129	1	41	41	NUM
fnp-5721	129	2	,	,	PUNCT
fnp-5721	129	3	613–630	613–630	NUM
fnp-5721	129	4	(	(	PUNCT
fnp-5721	129	5	2015	2015	NUM
fnp-5721	129	6	)	)	PUNCT
fnp-5721	129	7	.	.	PUNCT
fnp-5721	130	1	doi	doi	NOUN
fnp-5721	130	2	:	:	PUNCT
fnp-5721	130	3	https://doi.org/10.1111/nan.12189	https://doi.org/10.1111/nan.12189	PROPN
fnp-5721	130	4	21	21	NUM
fnp-5721	130	5	.	.	PUNCT
fnp-5721	131	1	cairns	cairns	PROPN
fnp-5721	131	2	,	,	PUNCT
fnp-5721	131	3	n.	n.	PROPN
fnp-5721	131	4	j.	j.	PROPN
fnp-5721	131	5	et	et	PROPN
fnp-5721	131	6	al	al	PROPN
fnp-5721	131	7	.	.	PUNCT
fnp-5721	132	1	patients	patient	NOUN
fnp-5721	132	2	with	with	ADP
fnp-5721	132	3	a	a	DET
fnp-5721	132	4	novel	novel	ADJ
fnp-5721	132	5	neurofilamentopathy	neurofilamentopathy	NOUN
fnp-5721	132	6	:	:	PUNCT
fnp-5721	132	7	dementia	dementia	NOUN
fnp-5721	132	8	with	with	ADP
fnp-5721	132	9	neurofilament	neurofilament	ADJ
fnp-5721	132	10	inclusions	inclusion	NOUN
fnp-5721	132	11	.	.	PUNCT
fnp-5721	133	1	neuroscience	neuroscience	NOUN
fnp-5721	133	2	letters	letter	NOUN
fnp-5721	133	3	341	341	NUM
fnp-5721	133	4	,	,	PUNCT
fnp-5721	133	5	177–180	177–180	NUM
fnp-5721	133	6	(	(	PUNCT
fnp-5721	133	7	2003	2003	NUM
fnp-5721	133	8	)	)	PUNCT
fnp-5721	133	9	.	.	PUNCT
fnp-5721	134	1	doi	doi	NOUN
fnp-5721	134	2	:	:	PUNCT
fnp-5721	134	3	https://doi.org/10.1016/s0304-3940(03)00100-9	https://doi.org/10.1016/s0304-3940(03)00100-9	PROPN
fnp-5721	134	4	22	22	NUM
fnp-5721	134	5	.	.	PUNCT
fnp-5721	135	1	gelpi	gelpi	NOUN
fnp-5721	135	2	,	,	PUNCT
fnp-5721	135	3	e.	e.	PROPN
fnp-5721	135	4	et	et	PROPN
fnp-5721	135	5	al	al	PROPN
fnp-5721	135	6	.	.	PROPN
fnp-5721	136	1	phenotypic	phenotypic	ADJ
fnp-5721	136	2	variability	variability	NOUN
fnp-5721	136	3	within	within	ADP
fnp-5721	136	4	the	the	DET
fnp-5721	136	5	inclusion	inclusion	NOUN
fnp-5721	136	6	body	body	NOUN
fnp-5721	136	7	spectrum	spectrum	NOUN
fnp-5721	136	8	of	of	ADP
fnp-5721	136	9	basophilic	basophilic	ADJ
fnp-5721	136	10	inclusion	inclusion	NOUN
fnp-5721	136	11	body	body	NOUN
fnp-5721	136	12	disease	disease	NOUN
fnp-5721	136	13	and	and	CCONJ
fnp-5721	136	14	neuronal	neuronal	ADJ
fnp-5721	136	15	intermediate	intermediate	ADJ
fnp-5721	136	16	filament	filament	NOUN
fnp-5721	136	17	inclusion	inclusion	NOUN
fnp-5721	136	18	disease	disease	NOUN
fnp-5721	136	19	in	in	ADP
fnp-5721	136	20	frontotemporal	frontotemporal	ADJ
fnp-5721	136	21	lobar	lobar	ADJ
fnp-5721	136	22	degenerations	degeneration	NOUN
fnp-5721	136	23	with	with	ADP
fnp-5721	136	24	fus	fus	ADJ
fnp-5721	136	25	-	-	PUNCT
fnp-5721	136	26	positive	positive	ADJ
fnp-5721	136	27	inclusions	inclusion	NOUN
fnp-5721	136	28	.	.	PUNCT
fnp-5721	137	1	j	j	PROPN
fnp-5721	137	2	neuropathol	neuropathol	PROPN
fnp-5721	137	3	exp	exp	PROPN
fnp-5721	137	4	neurol	neurol	NOUN
fnp-5721	137	5	71	71	NUM
fnp-5721	137	6	,	,	PUNCT
fnp-5721	137	7	795–805	795–805	NUM
fnp-5721	137	8	(	(	PUNCT
fnp-5721	137	9	2012	2012	NUM
fnp-5721	137	10	)	)	PUNCT
fnp-5721	137	11	.	.	PUNCT
fnp-5721	138	1	doi	doi	NOUN
fnp-5721	138	2	:	:	PUNCT
fnp-5721	138	3	https://doi.org/10.1097/nen.0b013e318266efb1	https://doi.org/10.1097/nen.0b013e318266efb1	NUM
fnp-5721	138	4	copyright	copyright	NOUN
fnp-5721	138	5	:	:	PUNCT
fnp-5721	138	6	©	©	PROPN
fnp-5721	138	7	2024	2024	NUM
fnp-5721	138	8	the	the	DET
fnp-5721	138	9	author(s	author(s	NOUN
fnp-5721	138	10	)	)	PUNCT
fnp-5721	138	11	.	.	PUNCT
fnp-5721	139	1	this	this	PRON
fnp-5721	139	2	is	be	AUX
fnp-5721	139	3	an	an	DET
fnp-5721	139	4	open	open	ADJ
fnp-5721	139	5	access	access	NOUN
fnp-5721	139	6	article	article	NOUN
fnp-5721	139	7	distributed	distribute	VERB
fnp-5721	139	8	under	under	ADP
fnp-5721	139	9	the	the	DET
fnp-5721	139	10	terms	term	NOUN
fnp-5721	139	11	of	of	ADP
fnp-5721	139	12	the	the	DET
fnp-5721	139	13	creative	creative	ADJ
fnp-5721	139	14	commons	common	NOUN
fnp-5721	139	15	attribution	attribution	NOUN
fnp-5721	139	16	4.0	4.0	NUM
fnp-5721	139	17	international	international	ADJ
fnp-5721	139	18	license	license	NOUN
fnp-5721	139	19	(	(	PUNCT
fnp-5721	139	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5721	139	21	)	)	PUNCT
fnp-5721	139	22	,	,	PUNCT
fnp-5721	139	23	which	which	PRON
fnp-5721	139	24	permits	permit	VERB
fnp-5721	139	25	unrestricted	unrestricted	ADJ
fnp-5721	139	26	use	use	NOUN
fnp-5721	139	27	,	,	PUNCT
fnp-5721	139	28	distribution	distribution	NOUN
fnp-5721	139	29	,	,	PUNCT
fnp-5721	139	30	and	and	CCONJ
fnp-5721	139	31	reproduction	reproduction	NOUN
fnp-5721	139	32	in	in	ADP
fnp-5721	139	33	any	any	DET
fnp-5721	139	34	medium	medium	NOUN
fnp-5721	139	35	,	,	PUNCT
fnp-5721	139	36	provided	provide	VERB
fnp-5721	139	37	the	the	DET
fnp-5721	139	38	original	original	ADJ
fnp-5721	139	39	author	author	NOUN
fnp-5721	139	40	and	and	CCONJ
fnp-5721	139	41	source	source	NOUN
fnp-5721	139	42	are	be	AUX
fnp-5721	139	43	credited	credit	VERB
fnp-5721	139	44	,	,	PUNCT
fnp-5721	139	45	a	a	DET
fnp-5721	139	46	link	link	NOUN
fnp-5721	139	47	to	to	ADP
fnp-5721	139	48	the	the	DET
fnp-5721	139	49	creative	creative	ADJ
fnp-5721	139	50	commons	common	NOUN
fnp-5721	139	51	license	license	NOUN
fnp-5721	139	52	is	be	AUX
fnp-5721	139	53	provided	provide	VERB
fnp-5721	139	54	,	,	PUNCT
fnp-5721	139	55	and	and	CCONJ
fnp-5721	139	56	any	any	DET
fnp-5721	139	57	changes	change	NOUN
fnp-5721	139	58	are	be	AUX
fnp-5721	139	59	indicated	indicate	VERB
fnp-5721	139	60	.	.	PUNCT
fnp-5721	140	1	the	the	DET
fnp-5721	140	2	creative	creative	ADJ
fnp-5721	140	3	commons	common	NOUN
fnp-5721	140	4	public	public	ADJ
fnp-5721	140	5	domain	domain	NOUN
fnp-5721	140	6	dedication	dedication	NOUN
fnp-5721	140	7	waiver	waiver	NOUN
fnp-5721	140	8	(	(	PUNCT
fnp-5721	140	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-5721	140	10	)	)	PUNCT
fnp-5721	140	11	applies	apply	VERB
fnp-5721	140	12	to	to	ADP
fnp-5721	140	13	the	the	DET
fnp-5721	140	14	data	datum	NOUN
fnp-5721	140	15	made	make	VERB
fnp-5721	140	16	available	available	ADJ
fnp-5721	140	17	in	in	ADP
fnp-5721	140	18	this	this	DET
fnp-5721	140	19	article	article	NOUN
fnp-5721	140	20	,	,	PUNCT
fnp-5721	140	21	unless	unless	SCONJ
fnp-5721	140	22	otherwise	otherwise	ADV
fnp-5721	140	23	stated	state	VERB
fnp-5721	140	24	.	.	PUNCT
