id	sid	tid	token	lemma	pos
fnp-5809	1	1	neurooncology	neurooncology	NOUN
fnp-5809	1	2	:	:	PUNCT
fnp-5809	1	3	2024	2024	NUM
fnp-5809	1	4	update	update	NOUN
fnp-5809	1	5	feel	feel	VERB
fnp-5809	1	6	free	free	ADJ
fnp-5809	1	7	to	to	PART
fnp-5809	1	8	add	add	VERB
fnp-5809	1	9	comments	comment	NOUN
fnp-5809	1	10	by	by	ADP
fnp-5809	1	11	clicking	click	VERB
fnp-5809	1	12	these	these	DET
fnp-5809	1	13	icons	icon	NOUN
fnp-5809	1	14	on	on	ADP
fnp-5809	1	15	the	the	DET
fnp-5809	1	16	sidebar	sidebar	NOUN
fnp-5809	1	17	free	free	ADJ
fnp-5809	1	18	neuropathology	neuropathology	NOUN
fnp-5809	1	19	5:21	5:21	NUM
fnp-5809	1	20	(	(	PUNCT
fnp-5809	1	21	2024	2024	NUM
fnp-5809	1	22	)	)	PUNCT
fnp-5809	1	23	review	review	VERB
fnp-5809	1	24	neurooncology	neurooncology	NOUN
fnp-5809	1	25	:	:	PUNCT
fnp-5809	1	26	2024	2024	NUM
fnp-5809	1	27	update	update	NOUN
fnp-5809	1	28	michel	michel	PROPN
fnp-5809	1	29	mittelbronn1–6	mittelbronn1–6	PROPN
fnp-5809	1	30	national	national	PROPN
fnp-5809	1	31	center	center	NOUN
fnp-5809	1	32	of	of	ADP
fnp-5809	1	33	pathology	pathology	NOUN
fnp-5809	1	34	(	(	PUNCT
fnp-5809	1	35	ncp	ncp	PROPN
fnp-5809	1	36	)	)	PUNCT
fnp-5809	1	37	,	,	PUNCT
fnp-5809	1	38	laboratoire	laboratoire	PROPN
fnp-5809	1	39	national	national	PROPN
fnp-5809	1	40	de	de	X
fnp-5809	1	41	santé	santé	X
fnp-5809	1	42	(	(	PUNCT
fnp-5809	1	43	lns	lns	PROPN
fnp-5809	1	44	)	)	PUNCT
fnp-5809	1	45	,	,	PUNCT
fnp-5809	1	46	dudelange	dudelange	NOUN
fnp-5809	1	47	,	,	PUNCT
fnp-5809	1	48	luxembourg	luxembourg	PROPN
fnp-5809	1	49	luxembourg	luxembourg	PROPN
fnp-5809	1	50	centre	centre	PROPN
fnp-5809	1	51	of	of	ADP
fnp-5809	1	52	neuropathology	neuropathology	NOUN
fnp-5809	1	53	(	(	PUNCT
fnp-5809	1	54	lcnp	lcnp	NOUN
fnp-5809	1	55	)	)	PUNCT
fnp-5809	1	56	,	,	PUNCT
fnp-5809	1	57	luxembourg	luxembourg	PROPN
fnp-5809	1	58	department	department	PROPN
fnp-5809	1	59	of	of	ADP
fnp-5809	1	60	oncology	oncology	NOUN
fnp-5809	1	61	(	(	PUNCT
fnp-5809	1	62	donc	donc	ADJ
fnp-5809	1	63	)	)	PUNCT
fnp-5809	1	64	,	,	PUNCT
fnp-5809	1	65	luxembourg	luxembourg	PROPN
fnp-5809	1	66	institute	institute	PROPN
fnp-5809	1	67	of	of	ADP
fnp-5809	1	68	health	health	PROPN
fnp-5809	1	69	(	(	PUNCT
fnp-5809	1	70	lih	lih	PROPN
fnp-5809	1	71	)	)	PUNCT
fnp-5809	1	72	,	,	PUNCT
fnp-5809	1	73	luxembourg	luxembourg	PROPN
fnp-5809	1	74	,	,	PUNCT
fnp-5809	1	75	luxembourg	luxembourg	PROPN
fnp-5809	1	76	department	department	PROPN
fnp-5809	1	77	of	of	ADP
fnp-5809	1	78	life	life	PROPN
fnp-5809	1	79	sciences	science	NOUN
fnp-5809	1	80	and	and	CCONJ
fnp-5809	1	81	medicine	medicine	NOUN
fnp-5809	1	82	,	,	PUNCT
fnp-5809	1	83	university	university	NOUN
fnp-5809	1	84	of	of	ADP
fnp-5809	1	85	luxembourg	luxembourg	PROPN
fnp-5809	1	86	,	,	PUNCT
fnp-5809	1	87	esch	esch	PROPN
fnp-5809	1	88	sur	sur	PROPN
fnp-5809	1	89	alzette	alzette	PROPN
fnp-5809	1	90	,	,	PUNCT
fnp-5809	1	91	luxembourg	luxembourg	PROPN
fnp-5809	1	92	luxembourg	luxembourg	PROPN
fnp-5809	1	93	centre	centre	PROPN
fnp-5809	1	94	for	for	ADP
fnp-5809	1	95	systems	system	NOUN
fnp-5809	1	96	biomedicine	biomedicine	NOUN
fnp-5809	1	97	(	(	PUNCT
fnp-5809	1	98	lcsb	lcsb	PROPN
fnp-5809	1	99	)	)	PUNCT
fnp-5809	1	100	,	,	PUNCT
fnp-5809	1	101	university	university	NOUN
fnp-5809	1	102	of	of	ADP
fnp-5809	1	103	luxembourg	luxembourg	PROPN
fnp-5809	1	104	,	,	PUNCT
fnp-5809	1	105	esch	esch	PROPN
fnp-5809	1	106	-	-	PUNCT
fnp-5809	1	107	sur	sur	PROPN
fnp-5809	1	108	-	-	PUNCT
fnp-5809	1	109	alzette	alzette	PROPN
fnp-5809	1	110	,	,	PUNCT
fnp-5809	1	111	luxembourg	luxembourg	PROPN
fnp-5809	1	112	faculty	faculty	NOUN
fnp-5809	1	113	of	of	ADP
fnp-5809	1	114	science	science	NOUN
fnp-5809	1	115	,	,	PUNCT
fnp-5809	1	116	technology	technology	NOUN
fnp-5809	1	117	and	and	CCONJ
fnp-5809	1	118	medicine	medicine	NOUN
fnp-5809	1	119	(	(	PUNCT
fnp-5809	1	120	fstm	fstm	PROPN
fnp-5809	1	121	)	)	PUNCT
fnp-5809	1	122	,	,	PUNCT
fnp-5809	1	123	university	university	NOUN
fnp-5809	1	124	of	of	ADP
fnp-5809	1	125	luxembourg	luxembourg	PROPN
fnp-5809	1	126	,	,	PUNCT
fnp-5809	1	127	esch	esch	PROPN
fnp-5809	1	128	-	-	PUNCT
fnp-5809	1	129	sur	sur	PROPN
fnp-5809	1	130	-	-	PUNCT
fnp-5809	1	131	alzette	alzette	NOUN
fnp-5809	1	132	,	,	PUNCT
fnp-5809	1	133	luxembourg	luxembourg	PROPN
fnp-5809	1	134	corresponding	corresponding	ADJ
fnp-5809	1	135	author	author	NOUN
fnp-5809	1	136	:	:	PUNCT
fnp-5809	1	137	michel	michel	PROPN
fnp-5809	1	138	mittelbronn	mittelbronn	PROPN
fnp-5809	1	139	·	·	PUNCT
fnp-5809	1	140	national	national	ADJ
fnp-5809	1	141	center	center	NOUN
fnp-5809	1	142	of	of	ADP
fnp-5809	1	143	pathology	pathology	NOUN
fnp-5809	1	144	(	(	PUNCT
fnp-5809	1	145	ncp	ncp	PROPN
fnp-5809	1	146	)	)	PUNCT
fnp-5809	1	147	and	and	CCONJ
fnp-5809	1	148	luxembourg	luxembourg	PROPN
fnp-5809	1	149	center	center	PROPN
fnp-5809	1	150	of	of	ADP
fnp-5809	1	151	neuropathology	neuropathology	NOUN
fnp-5809	1	152	(	(	PUNCT
fnp-5809	1	153	lcnp	lcnp	NOUN
fnp-5809	1	154	)	)	PUNCT
fnp-5809	1	155	·	·	PUNCT
fnp-5809	2	1	laboratoire	laboratoire	PROPN
fnp-5809	2	2	national	national	PROPN
fnp-5809	2	3	de	de	X
fnp-5809	2	4	santé	santé	X
fnp-5809	2	5	(	(	PUNCT
fnp-5809	2	6	lns	lns	PROPN
fnp-5809	2	7	)	)	PUNCT
fnp-5809	2	8	·	·	PUNCT
fnp-5809	2	9	1	1	X
fnp-5809	2	10	,	,	PUNCT
fnp-5809	2	11	rue	rue	X
fnp-5809	2	12	louis	louis	NOUN
fnp-5809	2	13	rech	rech	NOUN
fnp-5809	2	14	·	·	PUNCT
fnp-5809	2	15	3555	3555	NUM
fnp-5809	2	16	dudelange	dudelange	NOUN
fnp-5809	2	17	·	·	PUNCT
fnp-5809	2	18	luxembourg	luxembourg	PROPN
fnp-5809	3	1	michel.mittelbronn@uni.lu	michel.mittelbronn@uni.lu	PROPN
fnp-5809	3	2	submitted	submit	VERB
fnp-5809	3	3	:	:	PUNCT
fnp-5809	3	4	14	14	NUM
fnp-5809	3	5	august	august	PROPN
fnp-5809	3	6	2024	2024	NUM
fnp-5809	3	7	accepted	accept	VERB
fnp-5809	3	8	:	:	PUNCT
fnp-5809	3	9	08	08	NUM
fnp-5809	3	10	september	september	PROPN
fnp-5809	3	11	2024	2024	NUM
fnp-5809	3	12	copyedited	copyedit	VERB
fnp-5809	3	13	by	by	ADP
fnp-5809	3	14	:	:	PUNCT
fnp-5809	3	15	joão	joão	PROPN
fnp-5809	3	16	gama	gama	PROPN
fnp-5809	3	17	published	publish	VERB
fnp-5809	3	18	:	:	PUNCT
fnp-5809	3	19	27	27	NUM
fnp-5809	3	20	september	september	PROPN
fnp-5809	3	21	2024	2024	NUM
fnp-5809	3	22	https://doi.org/10.17879/freeneuropathology-2024-5809	https://doi.org/10.17879/freeneuropathology-2024-5809	PROPN
fnp-5809	3	23	keywords	keyword	VERB
fnp-5809	3	24	:	:	PUNCT
fnp-5809	3	25	neurooncology	neurooncology	NOUN
fnp-5809	3	26	,	,	PUNCT
fnp-5809	3	27	neuropathology	neuropathology	NOUN
fnp-5809	3	28	,	,	PUNCT
fnp-5809	3	29	brain	brain	NOUN
fnp-5809	3	30	tumors	tumor	NOUN
fnp-5809	3	31	,	,	PUNCT
fnp-5809	3	32	glioblastoma	glioblastoma	NOUN
fnp-5809	3	33	,	,	PUNCT
fnp-5809	3	34	brain	brain	NOUN
fnp-5809	3	35	metastasis	metastasis	NOUN
fnp-5809	3	36	abstract	abstract	ADJ
fnp-5809	3	37	as	as	ADP
fnp-5809	3	38	in	in	ADP
fnp-5809	3	39	previous	previous	ADJ
fnp-5809	3	40	years	year	NOUN
fnp-5809	3	41	,	,	PUNCT
fnp-5809	3	42	including	include	VERB
fnp-5809	3	43	2023	2023	NUM
fnp-5809	3	44	,	,	PUNCT
fnp-5809	3	45	a	a	DET
fnp-5809	3	46	major	major	ADJ
fnp-5809	3	47	focus	focus	NOUN
fnp-5809	3	48	in	in	ADP
fnp-5809	3	49	the	the	DET
fnp-5809	3	50	neurooncological	neurooncological	ADJ
fnp-5809	3	51	area	area	NOUN
fnp-5809	3	52	of	of	ADP
fnp-5809	3	53	neuropathology	neuropathology	NOUN
fnp-5809	3	54	was	be	AUX
fnp-5809	3	55	put	put	VERB
fnp-5809	3	56	on	on	ADP
fnp-5809	3	57	more	more	ADV
fnp-5809	3	58	precise	precise	ADJ
fnp-5809	3	59	and	and	CCONJ
fnp-5809	3	60	constantly	constantly	ADV
fnp-5809	3	61	faster	fast	ADV
fnp-5809	3	62	diagnostic	diagnostic	ADJ
fnp-5809	3	63	procedures	procedure	NOUN
fnp-5809	3	64	,	,	PUNCT
fnp-5809	3	65	even	even	ADV
fnp-5809	3	66	reaching	reach	VERB
fnp-5809	3	67	the	the	DET
fnp-5809	3	68	level	level	NOUN
fnp-5809	3	69	of	of	ADP
fnp-5809	3	70	ultra	ultra	ADJ
fnp-5809	3	71	-	-	ADJ
fnp-5809	3	72	fast	fast	ADJ
fnp-5809	3	73	intraoperative	intraoperative	ADJ
fnp-5809	3	74	diagnostics	diagnostic	NOUN
fnp-5809	3	75	based	base	VERB
fnp-5809	3	76	on	on	ADP
fnp-5809	3	77	methylation	methylation	NOUN
fnp-5809	3	78	profiling	profiling	NOUN
fnp-5809	3	79	.	.	PUNCT
fnp-5809	4	1	neuropathological	neuropathological	ADJ
fnp-5809	4	2	diagnostic	diagnostic	ADJ
fnp-5809	4	3	precision	precision	NOUN
fnp-5809	4	4	and	and	CCONJ
fnp-5809	4	5	clinical	clinical	ADJ
fnp-5809	4	6	follow	follow	NOUN
fnp-5809	4	7	-	-	PUNCT
fnp-5809	4	8	up	up	ADP
fnp-5809	4	9	treatment	treatment	NOUN
fnp-5809	4	10	has	have	AUX
fnp-5809	4	11	been	be	AUX
fnp-5809	4	12	further	far	ADV
fnp-5809	4	13	increased	increase	VERB
fnp-5809	4	14	by	by	ADP
fnp-5809	4	15	combining	combine	VERB
fnp-5809	4	16	dna	dna	PROPN
fnp-5809	4	17	methylation	methylation	NOUN
fnp-5809	4	18	profiling	profiling	NOUN
fnp-5809	4	19	with	with	ADP
fnp-5809	4	20	targeted	target	VERB
fnp-5809	4	21	panel	panel	NOUN
fnp-5809	4	22	sequencing	sequence	VERB
fnp-5809	4	23	.	.	PUNCT
fnp-5809	5	1	a	a	DET
fnp-5809	5	2	few	few	ADJ
fnp-5809	5	3	new	new	ADJ
fnp-5809	5	4	,	,	PUNCT
fnp-5809	5	5	molecularly	molecularly	ADV
fnp-5809	5	6	defined	define	VERB
fnp-5809	5	7	tumor	tumor	NOUN
fnp-5809	5	8	subtypes	subtype	NOUN
fnp-5809	5	9	have	have	AUX
fnp-5809	5	10	been	be	AUX
fnp-5809	5	11	proposed	propose	VERB
fnp-5809	5	12	,	,	PUNCT
fnp-5809	5	13	among	among	ADP
fnp-5809	5	14	others	other	NOUN
fnp-5809	5	15	,	,	PUNCT
fnp-5809	5	16	a	a	DET
fnp-5809	5	17	glioneuronal	glioneuronal	ADJ
fnp-5809	5	18	tumor	tumor	NOUN
fnp-5809	5	19	with	with	ADP
fnp-5809	5	20	atrx	atrx	PROPN
fnp-5809	5	21	alteration	alteration	NOUN
fnp-5809	5	22	,	,	PUNCT
fnp-5809	5	23	kinase	kinase	NOUN
fnp-5809	5	24	fusion	fusion	NOUN
fnp-5809	5	25	and	and	CCONJ
fnp-5809	5	26	anaplastic	anaplastic	ADJ
fnp-5809	5	27	features	feature	NOUN
fnp-5809	5	28	(	(	PUNCT
fnp-5809	5	29	in	in	ADP
fnp-5809	5	30	its	its	PRON
fnp-5809	5	31	abbreviated	abbreviate	VERB
fnp-5809	5	32	form	form	NOUN
fnp-5809	5	33	named	name	VERB
fnp-5809	5	34	gtaka	gtaka	NOUN
fnp-5809	5	35	)	)	PUNCT
fnp-5809	5	36	and	and	CCONJ
fnp-5809	5	37	the	the	DET
fnp-5809	5	38	de	de	PROPN
fnp-5809	5	39	novo	novo	PROPN
fnp-5809	5	40	replication	replication	NOUN
fnp-5809	5	41	repair	repair	NOUN
fnp-5809	5	42	deficient	deficient	ADJ
fnp-5809	5	43	glioblastoma	glioblastoma	NOUN
fnp-5809	5	44	,	,	PUNCT
fnp-5809	5	45	idh	idh	NOUN
fnp-5809	5	46	-	-	PUNCT
fnp-5809	5	47	wildtype	wildtype	NOUN
fnp-5809	5	48	both	both	CCONJ
fnp-5809	5	49	having	have	VERB
fnp-5809	5	50	either	either	CCONJ
fnp-5809	5	51	distinct	distinct	ADJ
fnp-5809	5	52	prognostic	prognostic	ADJ
fnp-5809	5	53	or	or	CCONJ
fnp-5809	5	54	therapeutic	therapeutic	ADJ
fnp-5809	5	55	implications	implication	NOUN
fnp-5809	5	56	.	.	PUNCT
fnp-5809	6	1	regarding	regard	VERB
fnp-5809	6	2	the	the	DET
fnp-5809	6	3	understanding	understanding	NOUN
fnp-5809	6	4	of	of	ADP
fnp-5809	6	5	brain	brain	NOUN
fnp-5809	6	6	tumor	tumor	NOUN
fnp-5809	6	7	development	development	NOUN
fnp-5809	6	8	and	and	CCONJ
fnp-5809	6	9	progression	progression	NOUN
fnp-5809	6	10	,	,	PUNCT
fnp-5809	6	11	several	several	ADJ
fnp-5809	6	12	novel	novel	ADJ
fnp-5809	6	13	mechanisms	mechanism	NOUN
fnp-5809	6	14	have	have	AUX
fnp-5809	6	15	been	be	AUX
fnp-5809	6	16	presented	present	VERB
fnp-5809	6	17	which	which	PRON
fnp-5809	6	18	might	might	AUX
fnp-5809	6	19	also	also	ADV
fnp-5809	6	20	be	be	AUX
fnp-5809	6	21	considered	consider	VERB
fnp-5809	6	22	as	as	ADP
fnp-5809	6	23	treatment	treatment	NOUN
fnp-5809	6	24	targets	target	NOUN
fnp-5809	6	25	in	in	ADP
fnp-5809	6	26	the	the	DET
fnp-5809	6	27	future	future	NOUN
fnp-5809	6	28	,	,	PUNCT
fnp-5809	6	29	such	such	ADJ
fnp-5809	6	30	as	as	ADP
fnp-5809	6	31	a	a	DET
fnp-5809	6	32	)	)	PUNCT
fnp-5809	6	33	autonomous	autonomous	ADJ
fnp-5809	6	34	rhythmical	rhythmical	ADJ
fnp-5809	6	35	ca2	ca2	PROPN
fnp-5809	6	36	+	+	PROPN
fnp-5809	6	37	oscillations	oscillation	NOUN
fnp-5809	6	38	in	in	ADP
fnp-5809	6	39	interconnected	interconnected	ADJ
fnp-5809	6	40	glioma	glioma	NOUN
fnp-5809	6	41	cell	cell	NOUN
fnp-5809	6	42	networks	network	NOUN
fnp-5809	6	43	driving	drive	VERB
fnp-5809	6	44	tumor	tumor	NOUN
fnp-5809	6	45	growth	growth	NOUN
fnp-5809	6	46	;	;	PUNCT
fnp-5809	6	47	b	b	X
fnp-5809	6	48	)	)	PUNCT
fnp-5809	6	49	transfer	transfer	NOUN
fnp-5809	6	50	of	of	ADP
fnp-5809	6	51	mitochondria	mitochondria	NOUN
fnp-5809	6	52	from	from	ADP
fnp-5809	6	53	normal	normal	ADJ
fnp-5809	6	54	astrocytes	astrocyte	NOUN
fnp-5809	6	55	to	to	ADP
fnp-5809	6	56	glioma	glioma	NOUN
fnp-5809	6	57	cells	cell	NOUN
fnp-5809	6	58	enhancing	enhance	VERB
fnp-5809	6	59	proliferation	proliferation	NOUN
fnp-5809	6	60	and	and	CCONJ
fnp-5809	6	61	self	self	NOUN
fnp-5809	6	62	-	-	PUNCT
fnp-5809	6	63	renewal	renewal	NOUN
fnp-5809	6	64	;	;	PUNCT
fnp-5809	6	65	c	c	X
fnp-5809	6	66	)	)	PUNCT
fnp-5809	6	67	brain	brain	NOUN
fnp-5809	6	68	endothelial	endothelial	ADJ
fnp-5809	6	69	cell	cell	NOUN
fnp-5809	6	70	remodeling	remodeling	NOUN
fnp-5809	6	71	upon	upon	SCONJ
fnp-5809	6	72	matrix	matrix	NOUN
fnp-5809	6	73	-	-	PUNCT
fnp-5809	6	74	metalloprotease	metalloprotease	NOUN
fnp-5809	6	75	9	9	NUM
fnp-5809	6	76	secretion	secretion	NOUN
fnp-5809	6	77	by	by	ADP
fnp-5809	6	78	tumor	tumor	NOUN
fnp-5809	6	79	cells	cell	NOUN
fnp-5809	6	80	metastasizing	metastasize	VERB
fnp-5809	6	81	into	into	ADP
fnp-5809	6	82	the	the	DET
fnp-5809	6	83	cns	cns	NOUN
fnp-5809	6	84	and	and	CCONJ
fnp-5809	6	85	d	d	NOUN
fnp-5809	6	86	)	)	PUNCT
fnp-5809	6	87	anti	anti	ADJ
fnp-5809	6	88	-	-	ADJ
fnp-5809	6	89	tumor	tumor	ADJ
fnp-5809	6	90	activity	activity	NOUN
fnp-5809	6	91	of	of	ADP
fnp-5809	6	92	microglia	microglia	NOUN
fnp-5809	6	93	in	in	ADP
fnp-5809	6	94	cns	cns	PROPN
fnp-5809	6	95	metastasis	metastasis	NOUN
fnp-5809	6	96	of	of	ADP
fnp-5809	6	97	breast	breast	NOUN
fnp-5809	6	98	cancer	cancer	NOUN
fnp-5809	6	99	.	.	PUNCT
fnp-5809	7	1	finally	finally	ADV
fnp-5809	7	2	,	,	PUNCT
fnp-5809	7	3	in	in	ADP
fnp-5809	7	4	contrast	contrast	NOUN
fnp-5809	7	5	to	to	ADP
fnp-5809	7	6	previous	previous	ADJ
fnp-5809	7	7	years	year	NOUN
fnp-5809	7	8	,	,	PUNCT
fnp-5809	7	9	several	several	ADJ
fnp-5809	7	10	very	very	ADV
fnp-5809	7	11	promising	promising	ADJ
fnp-5809	7	12	neurooncological	neurooncological	ADJ
fnp-5809	7	13	treatment	treatment	NOUN
fnp-5809	7	14	studies	study	NOUN
fnp-5809	7	15	have	have	AUX
fnp-5809	7	16	been	be	AUX
fnp-5809	7	17	conducted	conduct	VERB
fnp-5809	7	18	,	,	PUNCT
fnp-5809	7	19	focusing	focus	VERB
fnp-5809	7	20	on	on	ADP
fnp-5809	7	21	specific	specific	ADJ
fnp-5809	7	22	targets	target	NOUN
fnp-5809	7	23	such	such	ADJ
fnp-5809	7	24	as	as	ADP
fnp-5809	7	25	h3k27	h3k27	NOUN
fnp-5809	7	26	m	m	PROPN
fnp-5809	7	27	or	or	CCONJ
fnp-5809	7	28	idh1/2	idh1/2	ADJ
fnp-5809	7	29	mutations	mutation	NOUN
fnp-5809	7	30	for	for	ADP
fnp-5809	7	31	which	which	PRON
fnp-5809	7	32	a	a	DET
fnp-5809	7	33	proper	proper	ADJ
fnp-5809	7	34	neuropathological	neuropathological	ADJ
fnp-5809	7	35	assessment	assessment	NOUN
fnp-5809	7	36	is	be	AUX
fnp-5809	7	37	key	key	ADJ
fnp-5809	7	38	.	.	PUNCT
fnp-5809	8	1	the	the	DET
fnp-5809	8	2	continuous	continuous	ADJ
fnp-5809	8	3	translation	translation	NOUN
fnp-5809	8	4	of	of	ADP
fnp-5809	8	5	potential	potential	ADJ
fnp-5809	8	6	new	new	ADJ
fnp-5809	8	7	treatment	treatment	NOUN
fnp-5809	8	8	targets	target	NOUN
fnp-5809	8	9	using	use	VERB
fnp-5809	8	10	faster	fast	ADV
fnp-5809	8	11	and	and	CCONJ
fnp-5809	8	12	precise	precise	ADJ
fnp-5809	8	13	diagnostic	diagnostic	ADJ
fnp-5809	8	14	procedures	procedure	NOUN
fnp-5809	8	15	will	will	AUX
fnp-5809	8	16	further	far	ADV
fnp-5809	8	17	pave	pave	VERB
fnp-5809	8	18	the	the	DET
fnp-5809	8	19	way	way	NOUN
fnp-5809	8	20	for	for	ADP
fnp-5809	8	21	better	well	ADJ
fnp-5809	8	22	individualized	individualized	ADJ
fnp-5809	8	23	clinical	clinical	ADJ
fnp-5809	8	24	care	care	NOUN
fnp-5809	8	25	of	of	ADP
fnp-5809	8	26	neurooncological	neurooncological	ADJ
fnp-5809	8	27	patients	patient	NOUN
fnp-5809	8	28	.	.	PUNCT
fnp-5809	9	1	introduction	introduction	NOUN
fnp-5809	9	2	as	as	ADP
fnp-5809	9	3	in	in	ADP
fnp-5809	9	4	the	the	DET
fnp-5809	9	5	previous	previous	ADJ
fnp-5809	9	6	year	year	NOUN
fnp-5809	9	7	,	,	PUNCT
fnp-5809	9	8	the	the	DET
fnp-5809	9	9	author	author	NOUN
fnp-5809	9	10	’s	’s	PART
fnp-5809	9	11	aim	aim	NOUN
fnp-5809	9	12	for	for	ADP
fnp-5809	9	13	the	the	DET
fnp-5809	9	14	selection	selection	NOUN
fnp-5809	9	15	of	of	ADP
fnp-5809	9	16	the	the	DET
fnp-5809	9	17	“	"	PUNCT
fnp-5809	9	18	top	top	ADJ
fnp-5809	9	19	ten	ten	NUM
fnp-5809	9	20	”	"	PUNCT
fnp-5809	9	21	paper	paper	NOUN
fnp-5809	9	22	series	series	NOUN
fnp-5809	9	23	in	in	ADP
fnp-5809	9	24	the	the	DET
fnp-5809	9	25	field	field	NOUN
fnp-5809	9	26	of	of	ADP
fnp-5809	9	27	neurooncology	neurooncology	NOUN
fnp-5809	9	28	was	be	AUX
fnp-5809	9	29	to	to	PART
fnp-5809	9	30	select	select	VERB
fnp-5809	9	31	an	an	DET
fnp-5809	9	32	equilibrated	equilibrated	ADJ
fnp-5809	9	33	mix	mix	NOUN
fnp-5809	9	34	of	of	ADP
fnp-5809	9	35	high	high	ADJ
fnp-5809	9	36	-	-	PUNCT
fnp-5809	9	37	quality	quality	NOUN
fnp-5809	9	38	manuscripts	manuscript	NOUN
fnp-5809	9	39	that	that	PRON
fnp-5809	9	40	provide	provide	VERB
fnp-5809	9	41	new	new	ADJ
fnp-5809	9	42	tumor	tumor	NOUN
fnp-5809	9	43	biological	biological	ADJ
fnp-5809	9	44	concepts	concept	NOUN
fnp-5809	9	45	,	,	PUNCT
fnp-5809	9	46	new	new	ADJ
fnp-5809	9	47	tumor	tumor	NOUN
fnp-5809	9	48	entities	entity	NOUN
fnp-5809	9	49	,	,	PUNCT
fnp-5809	9	50	new	new	ADJ
fnp-5809	9	51	diagnostic	diagnostic	ADJ
fnp-5809	9	52	tools	tool	NOUN
fnp-5809	9	53	or	or	CCONJ
fnp-5809	9	54	approaches	approach	NOUN
fnp-5809	9	55	,	,	PUNCT
fnp-5809	9	56	and	and	CCONJ
fnp-5809	9	57	clinical	clinical	ADJ
fnp-5809	9	58	studies	study	NOUN
fnp-5809	9	59	with	with	ADP
fnp-5809	9	60	specific	specific	ADJ
fnp-5809	9	61	targeted	target	VERB
fnp-5809	9	62	approaches	approach	NOUN
fnp-5809	9	63	,	,	PUNCT
fnp-5809	9	64	all	all	PRON
fnp-5809	9	65	touching	touch	VERB
fnp-5809	9	66	the	the	DET
fnp-5809	9	67	field	field	NOUN
fnp-5809	9	68	of	of	ADP
fnp-5809	9	69	neuropathology	neuropathology	NOUN
fnp-5809	9	70	.	.	PUNCT
fnp-5809	10	1	this	this	PRON
fnp-5809	10	2	should	should	AUX
fnp-5809	10	3	not	not	PART
fnp-5809	10	4	at	at	ADV
fnp-5809	10	5	all	all	ADV
fnp-5809	10	6	devalue	devalue	VERB
fnp-5809	10	7	excellent	excellent	ADJ
fnp-5809	10	8	papers	paper	NOUN
fnp-5809	10	9	in	in	ADP
fnp-5809	10	10	the	the	DET
fnp-5809	10	11	field	field	NOUN
fnp-5809	10	12	of	of	ADP
fnp-5809	10	13	neurooncology	neurooncology	NOUN
fnp-5809	10	14	with	with	ADP
fnp-5809	10	15	a	a	DET
fnp-5809	10	16	different	different	ADJ
fnp-5809	10	17	focus	focus	NOUN
fnp-5809	10	18	,	,	PUNCT
fnp-5809	10	19	such	such	ADJ
fnp-5809	10	20	as	as	ADP
fnp-5809	10	21	neuroradiology	neuroradiology	NOUN
fnp-5809	10	22	,	,	PUNCT
fnp-5809	10	23	neurophysiology	neurophysiology	NOUN
fnp-5809	10	24	or	or	CCONJ
fnp-5809	10	25	neuropsychology	neuropsychology	NOUN
fnp-5809	10	26	,	,	PUNCT
fnp-5809	10	27	but	but	CCONJ
fnp-5809	10	28	rather	rather	ADV
fnp-5809	10	29	focus	focus	VERB
fnp-5809	10	30	on	on	ADP
fnp-5809	10	31	the	the	DET
fnp-5809	10	32	central	central	ADJ
fnp-5809	10	33	aims	aim	NOUN
fnp-5809	10	34	and	and	CCONJ
fnp-5809	10	35	scope	scope	NOUN
fnp-5809	10	36	of	of	ADP
fnp-5809	10	37	free	free	ADJ
fnp-5809	10	38	neuropathology	neuropathology	NOUN
fnp-5809	10	39	,	,	PUNCT
fnp-5809	10	40	namely	namely	ADV
fnp-5809	10	41	morphological	morphological	ADJ
fnp-5809	10	42	or	or	CCONJ
fnp-5809	10	43	molecular	molecular	ADJ
fnp-5809	10	44	techniques	technique	NOUN
fnp-5809	10	45	based	base	VERB
fnp-5809	10	46	on	on	ADP
fnp-5809	10	47	biospecimens	biospecimen	NOUN
fnp-5809	10	48	such	such	ADJ
fnp-5809	10	49	as	as	ADP
fnp-5809	10	50	tissues	tissue	NOUN
fnp-5809	10	51	,	,	PUNCT
fnp-5809	10	52	cells	cell	NOUN
fnp-5809	10	53	of	of	ADP
fnp-5809	10	54	fluids	fluid	NOUN
fnp-5809	10	55	.	.	PUNCT
fnp-5809	11	1	the	the	DET
fnp-5809	11	2	search	search	NOUN
fnp-5809	11	3	strategy	strategy	NOUN
fnp-5809	11	4	for	for	ADP
fnp-5809	11	5	this	this	DET
fnp-5809	11	6	year	year	NOUN
fnp-5809	11	7	’s	’s	PART
fnp-5809	11	8	“	"	PUNCT
fnp-5809	11	9	neurooncology	neurooncology	NOUN
fnp-5809	11	10	update	update	NOUN
fnp-5809	11	11	”	"	PUNCT
fnp-5809	11	12	series	series	NOUN
fnp-5809	11	13	was	be	AUX
fnp-5809	11	14	similar	similar	ADJ
fnp-5809	11	15	as	as	SCONJ
fnp-5809	11	16	previously	previously	ADV
fnp-5809	11	17	described	describe	VERB
fnp-5809	11	18	[	[	X
fnp-5809	11	19	mittelbronn	mittelbronn	NOUN
fnp-5809	11	20	,	,	PUNCT
fnp-5809	11	21	2023	2023	NUM
fnp-5809	11	22	]	]	PUNCT
fnp-5809	11	23	.	.	PUNCT
fnp-5809	12	1	whereas	whereas	SCONJ
fnp-5809	12	2	in	in	ADP
fnp-5809	12	3	2022	2022	NUM
fnp-5809	12	4	,	,	PUNCT
fnp-5809	12	5	a	a	DET
fnp-5809	12	6	major	major	ADJ
fnp-5809	12	7	focus	focus	NOUN
fnp-5809	12	8	was	be	AUX
fnp-5809	12	9	put	put	VERB
fnp-5809	12	10	on	on	ADP
fnp-5809	12	11	studies	study	NOUN
fnp-5809	12	12	focusing	focus	VERB
fnp-5809	12	13	on	on	ADP
fnp-5809	12	14	profiling	profiling	NOUN
fnp-5809	12	15	,	,	PUNCT
fnp-5809	12	16	“	"	PUNCT
fnp-5809	12	17	omics	omic	NOUN
fnp-5809	12	18	”	"	PUNCT
fnp-5809	12	19	and	and	CCONJ
fnp-5809	12	20	new	new	ADJ
fnp-5809	12	21	diagnostic	diagnostic	ADJ
fnp-5809	12	22	applications	application	NOUN
fnp-5809	12	23	,	,	PUNCT
fnp-5809	12	24	many	many	ADJ
fnp-5809	12	25	more	more	ADJ
fnp-5809	12	26	cutting	cutting	NOUN
fnp-5809	12	27	-	-	PUNCT
fnp-5809	12	28	edge	edge	NOUN
fnp-5809	12	29	studies	study	NOUN
fnp-5809	12	30	presenting	present	VERB
fnp-5809	12	31	new	new	ADJ
fnp-5809	12	32	tumor	tumor	NOUN
fnp-5809	12	33	biological	biological	ADJ
fnp-5809	12	34	mechanisms	mechanism	NOUN
fnp-5809	12	35	in	in	ADP
fnp-5809	12	36	the	the	DET
fnp-5809	12	37	field	field	NOUN
fnp-5809	12	38	of	of	ADP
fnp-5809	12	39	neurooncology	neurooncology	NOUN
fnp-5809	12	40	were	be	AUX
fnp-5809	12	41	published	publish	VERB
fnp-5809	12	42	in	in	ADP
fnp-5809	12	43	2023	2023	NUM
fnp-5809	12	44	.	.	PUNCT
fnp-5809	13	1	one	one	NUM
fnp-5809	13	2	point	point	NOUN
fnp-5809	13	3	that	that	PRON
fnp-5809	13	4	negatively	negatively	ADV
fnp-5809	13	5	struck	strike	VERB
fnp-5809	13	6	the	the	DET
fnp-5809	13	7	author	author	NOUN
fnp-5809	13	8	last	last	ADJ
fnp-5809	13	9	year	year	NOUN
fnp-5809	13	10	was	be	AUX
fnp-5809	13	11	the	the	DET
fnp-5809	13	12	fact	fact	NOUN
fnp-5809	13	13	that	that	SCONJ
fnp-5809	13	14	despite	despite	SCONJ
fnp-5809	13	15	the	the	DET
fnp-5809	13	16	large	large	ADJ
fnp-5809	13	17	amount	amount	NOUN
fnp-5809	13	18	of	of	ADP
fnp-5809	13	19	profiling	profile	VERB
fnp-5809	13	20	data	datum	NOUN
fnp-5809	13	21	,	,	PUNCT
fnp-5809	13	22	very	very	ADV
fnp-5809	13	23	few	few	ADJ
fnp-5809	13	24	studies	study	NOUN
fnp-5809	13	25	aimed	aim	VERB
fnp-5809	13	26	at	at	ADP
fnp-5809	13	27	translating	translate	VERB
fnp-5809	13	28	those	those	DET
fnp-5809	13	29	findings	finding	NOUN
fnp-5809	13	30	into	into	ADP
fnp-5809	13	31	clinical	clinical	ADJ
fnp-5809	13	32	applications	application	NOUN
fnp-5809	13	33	.	.	PUNCT
fnp-5809	14	1	it	it	PRON
fnp-5809	14	2	is	be	AUX
fnp-5809	14	3	a	a	DET
fnp-5809	14	4	central	central	ADJ
fnp-5809	14	5	paradigm	paradigm	NOUN
fnp-5809	14	6	of	of	ADP
fnp-5809	14	7	our	our	PRON
fnp-5809	14	8	field	field	NOUN
fnp-5809	14	9	that	that	PRON
fnp-5809	14	10	an	an	DET
fnp-5809	14	11	excellent	excellent	ADJ
fnp-5809	14	12	clinical	clinical	ADJ
fnp-5809	14	13	treatment	treatment	NOUN
fnp-5809	14	14	necessitates	necessitate	VERB
fnp-5809	14	15	precise	precise	ADJ
fnp-5809	14	16	and	and	CCONJ
fnp-5809	14	17	fast	fast	ADJ
fnp-5809	14	18	diagnosis	diagnosis	NOUN
fnp-5809	14	19	as	as	ADV
fnp-5809	14	20	well	well	ADV
fnp-5809	14	21	as	as	ADP
fnp-5809	14	22	identification	identification	NOUN
fnp-5809	14	23	of	of	ADP
fnp-5809	14	24	specific	specific	ADJ
fnp-5809	14	25	targets	target	NOUN
fnp-5809	14	26	,	,	PUNCT
fnp-5809	14	27	allowing	allow	VERB
fnp-5809	14	28	for	for	ADP
fnp-5809	14	29	the	the	DET
fnp-5809	14	30	best	good	ADJ
fnp-5809	14	31	individualized	individualized	ADJ
fnp-5809	14	32	clinical	clinical	ADJ
fnp-5809	14	33	care	care	NOUN
fnp-5809	14	34	.	.	PUNCT
fnp-5809	15	1	it	it	PRON
fnp-5809	15	2	is	be	AUX
fnp-5809	15	3	gratifying	gratify	VERB
fnp-5809	15	4	to	to	PART
fnp-5809	15	5	see	see	VERB
fnp-5809	15	6	the	the	DET
fnp-5809	15	7	development	development	NOUN
fnp-5809	15	8	and	and	CCONJ
fnp-5809	15	9	implementation	implementation	NOUN
fnp-5809	15	10	of	of	ADP
fnp-5809	15	11	new	new	ADJ
fnp-5809	15	12	treatment	treatment	NOUN
fnp-5809	15	13	approaches	approach	NOUN
fnp-5809	15	14	to	to	PART
fnp-5809	15	15	address	address	VERB
fnp-5809	15	16	molecular	molecular	ADJ
fnp-5809	15	17	targets	target	NOUN
fnp-5809	15	18	that	that	PRON
fnp-5809	15	19	have	have	AUX
fnp-5809	15	20	been	be	AUX
fnp-5809	15	21	introduced	introduce	VERB
fnp-5809	15	22	in	in	ADP
fnp-5809	15	23	daily	daily	ADJ
fnp-5809	15	24	neuropathological	neuropathological	ADJ
fnp-5809	15	25	routine	routine	NOUN
fnp-5809	15	26	over	over	ADP
fnp-5809	15	27	recent	recent	ADJ
fnp-5809	15	28	years	year	NOUN
fnp-5809	15	29	.	.	PUNCT
fnp-5809	16	1	although	although	SCONJ
fnp-5809	16	2	this	this	DET
fnp-5809	16	3	year	year	NOUN
fnp-5809	16	4	’s	’s	PART
fnp-5809	16	5	series	series	NOUN
fnp-5809	16	6	also	also	ADV
fnp-5809	16	7	presents	present	VERB
fnp-5809	16	8	some	some	DET
fnp-5809	16	9	new	new	ADJ
fnp-5809	16	10	tumor	tumor	NOUN
fnp-5809	16	11	subtypes	subtype	NOUN
fnp-5809	16	12	and	and	CCONJ
fnp-5809	16	13	further	further	ADJ
fnp-5809	16	14	improvements	improvement	NOUN
fnp-5809	16	15	in	in	ADP
fnp-5809	16	16	diagnostic	diagnostic	ADJ
fnp-5809	16	17	procedures	procedure	NOUN
fnp-5809	16	18	,	,	PUNCT
fnp-5809	16	19	a	a	DET
fnp-5809	16	20	larger	large	ADJ
fnp-5809	16	21	part	part	NOUN
fnp-5809	16	22	focuses	focus	VERB
fnp-5809	16	23	on	on	ADP
fnp-5809	16	24	novel	novel	NOUN
fnp-5809	16	25	,	,	PUNCT
fnp-5809	16	26	more	more	ADV
fnp-5809	16	27	basic	basic	ADJ
fnp-5809	16	28	tumor	tumor	ADJ
fnp-5809	16	29	biological	biological	ADJ
fnp-5809	16	30	mechanisms	mechanism	NOUN
fnp-5809	16	31	,	,	PUNCT
fnp-5809	16	32	as	as	ADV
fnp-5809	16	33	well	well	ADV
fnp-5809	16	34	as	as	ADP
fnp-5809	16	35	very	very	ADV
fnp-5809	16	36	promising	promising	ADJ
fnp-5809	16	37	clinical	clinical	ADJ
fnp-5809	16	38	studies	study	NOUN
fnp-5809	16	39	that	that	PRON
fnp-5809	16	40	aim	aim	VERB
fnp-5809	16	41	to	to	PART
fnp-5809	16	42	treat	treat	VERB
fnp-5809	16	43	brain	brain	NOUN
fnp-5809	16	44	tumors	tumor	NOUN
fnp-5809	16	45	in	in	ADP
fnp-5809	16	46	a	a	DET
fnp-5809	16	47	more	more	ADV
fnp-5809	16	48	specific	specific	ADJ
fnp-5809	16	49	and	and	CCONJ
fnp-5809	16	50	individualized	individualized	ADJ
fnp-5809	16	51	manner	manner	NOUN
fnp-5809	16	52	to	to	PART
fnp-5809	16	53	complement	complement	VERB
fnp-5809	16	54	or	or	CCONJ
fnp-5809	16	55	even	even	ADV
fnp-5809	16	56	replace	replace	VERB
fnp-5809	16	57	the	the	DET
fnp-5809	16	58	classic	classic	ADJ
fnp-5809	16	59	neurooncological	neurooncological	ADJ
fnp-5809	16	60	treatment	treatment	NOUN
fnp-5809	16	61	triad	triad	NUM
fnp-5809	16	62	of	of	ADP
fnp-5809	16	63	surgery	surgery	NOUN
fnp-5809	16	64	,	,	PUNCT
fnp-5809	16	65	radioand	radioand	PROPN
fnp-5809	16	66	chemotherapy	chemotherapy	NOUN
fnp-5809	16	67	.	.	PUNCT
fnp-5809	17	1	with	with	ADP
fnp-5809	17	2	this	this	PRON
fnp-5809	17	3	,	,	PUNCT
fnp-5809	17	4	the	the	DET
fnp-5809	17	5	“	"	PUNCT
fnp-5809	17	6	top	top	ADJ
fnp-5809	17	7	ten	ten	NUM
fnp-5809	17	8	”	"	PUNCT
fnp-5809	17	9	series	series	NOUN
fnp-5809	17	10	in	in	ADP
fnp-5809	17	11	neurooncology	neurooncology	NOUN
fnp-5809	17	12	for	for	ADP
fnp-5809	17	13	2023	2023	NUM
fnp-5809	17	14	reads	read	NOUN
fnp-5809	17	15	as	as	SCONJ
fnp-5809	17	16	follows	follow	VERB
fnp-5809	17	17	:	:	PUNCT
fnp-5809	17	18	frequency	frequency	NOUN
fnp-5809	17	19	-	-	PUNCT
fnp-5809	17	20	dependent	dependent	ADJ
fnp-5809	17	21	mapk	mapk	NOUN
fnp-5809	17	22	and	and	CCONJ
fnp-5809	17	23	nfkb	nfkb	PROPN
fnp-5809	17	24	pathway	pathway	NOUN
fnp-5809	17	25	-	-	PUNCT
fnp-5809	17	26	activation	activation	NOUN
fnp-5809	17	27	by	by	ADP
fnp-5809	17	28	rhythmic	rhythmic	ADJ
fnp-5809	17	29	ca2	ca2	PROPN
fnp-5809	17	30	+	+	PROPN
fnp-5809	17	31	oscillations	oscillation	NOUN
fnp-5809	17	32	as	as	ADP
fnp-5809	17	33	potential	potential	ADJ
fnp-5809	17	34	treatment	treatment	NOUN
fnp-5809	17	35	target	target	NOUN
fnp-5809	17	36	in	in	ADP
fnp-5809	17	37	glioma	glioma	NOUN
fnp-5809	18	1	[	[	X
fnp-5809	18	2	hausmann	hausmann	PROPN
fnp-5809	18	3	et	et	PROPN
fnp-5809	18	4	al	al	PROPN
fnp-5809	18	5	.	.	PROPN
fnp-5809	18	6	,	,	PUNCT
fnp-5809	18	7	2023	2023	NUM
fnp-5809	18	8	]	]	PUNCT
fnp-5809	18	9	.	.	PUNCT
fnp-5809	19	1	gap43	gap43	NOUN
fnp-5809	19	2	-	-	PUNCT
fnp-5809	19	3	dependent	dependent	ADJ
fnp-5809	19	4	transfer	transfer	NOUN
fnp-5809	19	5	of	of	ADP
fnp-5809	19	6	mitochondria	mitochondria	NOUN
fnp-5809	19	7	from	from	ADP
fnp-5809	19	8	astrocytes	astrocyte	NOUN
fnp-5809	19	9	to	to	ADP
fnp-5809	19	10	glioma	glioma	NOUN
fnp-5809	19	11	cells	cell	NOUN
fnp-5809	19	12	increasing	increase	VERB
fnp-5809	19	13	cellular	cellular	ADJ
fnp-5809	19	14	proliferation	proliferation	NOUN
fnp-5809	19	15	and	and	CCONJ
fnp-5809	19	16	self	self	NOUN
fnp-5809	19	17	-	-	PUNCT
fnp-5809	19	18	renewal	renewal	NOUN
fnp-5809	19	19	[	[	X
fnp-5809	19	20	watson	watson	PROPN
fnp-5809	19	21	et	et	PROPN
fnp-5809	19	22	al	al	PROPN
fnp-5809	19	23	.	.	PROPN
fnp-5809	19	24	,	,	PUNCT
fnp-5809	19	25	2023	2023	NUM
fnp-5809	19	26	]	]	PUNCT
fnp-5809	19	27	.	.	PUNCT
fnp-5809	20	1	brain	brain	NOUN
fnp-5809	20	2	endothelial	endothelial	ADJ
fnp-5809	20	3	cell	cell	NOUN
fnp-5809	20	4	remodeling	remodeling	NOUN
fnp-5809	20	5	by	by	ADP
fnp-5809	20	6	cns	cns	NOUN
fnp-5809	20	7	metastatic	metastatic	ADJ
fnp-5809	20	8	cell	cell	NOUN
fnp-5809	20	9	-	-	PUNCT
fnp-5809	20	10	derived	derive	VERB
fnp-5809	20	11	matrix	matrix	NOUN
fnp-5809	20	12	-	-	PUNCT
fnp-5809	20	13	metalloprotease	metalloprotease	NOUN
fnp-5809	20	14	9	9	NUM
fnp-5809	20	15	(	(	PUNCT
fnp-5809	20	16	mmp9	mmp9	PROPN
fnp-5809	20	17	)	)	PUNCT
fnp-5809	20	18	as	as	ADP
fnp-5809	20	19	mechanism	mechanism	NOUN
fnp-5809	20	20	for	for	ADP
fnp-5809	20	21	extravasation	extravasation	NOUN
fnp-5809	21	1	[	[	X
fnp-5809	21	2	karreman	karreman	NOUN
fnp-5809	21	3	et	et	PROPN
fnp-5809	21	4	al	al	PROPN
fnp-5809	21	5	.	.	PROPN
fnp-5809	21	6	,	,	PUNCT
fnp-5809	21	7	2023	2023	NUM
fnp-5809	21	8	]	]	PUNCT
fnp-5809	21	9	.	.	PUNCT
fnp-5809	22	1	microglia	microglia	PROPN
fnp-5809	22	2	suppresses	suppress	VERB
fnp-5809	22	3	brain	brain	NOUN
fnp-5809	22	4	metastasis	metastasis	NOUN
fnp-5809	22	5	formation	formation	NOUN
fnp-5809	22	6	in	in	ADP
fnp-5809	22	7	breast	breast	NOUN
fnp-5809	22	8	cancer	cancer	NOUN
fnp-5809	23	1	[	[	X
fnp-5809	23	2	evans	evans	PROPN
fnp-5809	23	3	et	et	PROPN
fnp-5809	23	4	al	al	PROPN
fnp-5809	23	5	.	.	PROPN
fnp-5809	23	6	,	,	PUNCT
fnp-5809	23	7	2023	2023	NUM
fnp-5809	23	8	]	]	PUNCT
fnp-5809	23	9	.	.	PUNCT
fnp-5809	24	1	proposal	proposal	NOUN
fnp-5809	24	2	of	of	ADP
fnp-5809	24	3	a	a	DET
fnp-5809	24	4	new	new	ADJ
fnp-5809	24	5	tumor	tumor	NOUN
fnp-5809	24	6	entity	entity	NOUN
fnp-5809	24	7	:	:	PUNCT
fnp-5809	24	8	glioneuronal	glioneuronal	ADJ
fnp-5809	24	9	tumor	tumor	NOUN
fnp-5809	24	10	with	with	ADP
fnp-5809	24	11	atrx	atrx	PROPN
fnp-5809	24	12	alteration	alteration	NOUN
fnp-5809	24	13	,	,	PUNCT
fnp-5809	24	14	ntrk	ntrk	NOUN
fnp-5809	24	15	gene	gene	NOUN
fnp-5809	24	16	fusion	fusion	NOUN
fnp-5809	24	17	and	and	CCONJ
fnp-5809	24	18	anaplastic	anaplastic	ADJ
fnp-5809	24	19	features	feature	NOUN
fnp-5809	24	20	(	(	PUNCT
fnp-5809	24	21	gtaka	gtaka	NOUN
fnp-5809	24	22	)	)	PUNCT
fnp-5809	25	1	[	[	X
fnp-5809	25	2	bogumil	bogumil	PROPN
fnp-5809	25	3	et	et	PROPN
fnp-5809	25	4	al	al	PROPN
fnp-5809	25	5	.	.	PROPN
fnp-5809	25	6	,	,	PUNCT
fnp-5809	25	7	2023	2023	NUM
fnp-5809	25	8	]	]	PUNCT
fnp-5809	25	9	.	.	PUNCT
fnp-5809	26	1	“	"	PUNCT
fnp-5809	26	2	de	de	X
fnp-5809	26	3	novo	novo	NOUN
fnp-5809	26	4	replication	replication	NOUN
fnp-5809	26	5	repair	repair	NOUN
fnp-5809	26	6	deficient	deficient	ADJ
fnp-5809	26	7	glioblastoma	glioblastoma	NOUN
fnp-5809	26	8	,	,	PUNCT
fnp-5809	26	9	idh	idh	PROPN
fnp-5809	26	10	wildtype	wildtype	NOUN
fnp-5809	26	11	”	"	PUNCT
fnp-5809	26	12	:	:	PUNCT
fnp-5809	26	13	a	a	DET
fnp-5809	26	14	new	new	ADJ
fnp-5809	26	15	glioblastoma	glioblastoma	NOUN
fnp-5809	26	16	subtype	subtype	NOUN
fnp-5809	26	17	with	with	ADP
fnp-5809	26	18	implications	implication	NOUN
fnp-5809	26	19	for	for	ADP
fnp-5809	26	20	targeted	target	VERB
fnp-5809	26	21	treatment	treatment	NOUN
fnp-5809	26	22	[	[	X
fnp-5809	26	23	hadad	hadad	PROPN
fnp-5809	26	24	et	et	PROPN
fnp-5809	26	25	al	al	PROPN
fnp-5809	26	26	.	.	PROPN
fnp-5809	26	27	,	,	PUNCT
fnp-5809	26	28	2023	2023	NUM
fnp-5809	26	29	]	]	PUNCT
fnp-5809	26	30	.	.	PUNCT
fnp-5809	27	1	ultra	ultra	ADJ
fnp-5809	27	2	-	-	ADJ
fnp-5809	27	3	fast	fast	ADJ
fnp-5809	27	4	,	,	PUNCT
fnp-5809	27	5	machine	machine	NOUN
fnp-5809	27	6	-	-	PUNCT
fnp-5809	27	7	learning	learning	NOUN
fnp-5809	27	8	based	base	VERB
fnp-5809	27	9	intraoperative	intraoperative	ADJ
fnp-5809	27	10	methylation	methylation	NOUN
fnp-5809	27	11	profiling	profiling	NOUN
fnp-5809	28	1	[	[	X
fnp-5809	28	2	vermeulen	vermeulen	PROPN
fnp-5809	28	3	et	et	PROPN
fnp-5809	28	4	al	al	PROPN
fnp-5809	28	5	.	.	PROPN
fnp-5809	28	6	,	,	PUNCT
fnp-5809	28	7	2023	2023	NUM
fnp-5809	28	8	]	]	PUNCT
fnp-5809	28	9	.	.	PUNCT
fnp-5809	29	1	multiomics	multiomics	PROPN
fnp-5809	29	2	neuropathology	neuropathology	NOUN
fnp-5809	29	3	improving	improve	VERB
fnp-5809	29	4	diagnostic	diagnostic	ADJ
fnp-5809	29	5	precision	precision	NOUN
fnp-5809	29	6	,	,	PUNCT
fnp-5809	29	7	targeted	target	VERB
fnp-5809	29	8	therapy	therapy	NOUN
fnp-5809	29	9	and	and	CCONJ
fnp-5809	29	10	detection	detection	NOUN
fnp-5809	29	11	of	of	ADP
fnp-5809	29	12	cancer	cancer	NOUN
fnp-5809	29	13	predisposition	predisposition	NOUN
fnp-5809	29	14	syndromes	syndrome	NOUN
fnp-5809	29	15	in	in	ADP
fnp-5809	29	16	pediatric	pediatric	ADJ
fnp-5809	29	17	neurooncology	neurooncology	NOUN
fnp-5809	30	1	[	[	X
fnp-5809	30	2	sturm	sturm	PROPN
fnp-5809	30	3	et	et	PROPN
fnp-5809	30	4	al	al	PROPN
fnp-5809	30	5	.	.	PROPN
fnp-5809	30	6	,	,	PUNCT
fnp-5809	30	7	2023	2023	NUM
fnp-5809	30	8	]	]	PUNCT
fnp-5809	30	9	.	.	PUNCT
fnp-5809	31	1	clinical	clinical	ADJ
fnp-5809	31	2	vaccination	vaccination	NOUN
fnp-5809	31	3	study	study	NOUN
fnp-5809	31	4	targeting	target	VERB
fnp-5809	31	5	h3k27	h3k27	PRON
fnp-5809	31	6	m	m	VERB
fnp-5809	31	7	in	in	ADP
fnp-5809	31	8	adult	adult	NOUN
fnp-5809	31	9	diffuse	diffuse	NOUN
fnp-5809	31	10	midline	midline	NOUN
fnp-5809	31	11	glioma	glioma	NOUN
fnp-5809	32	1	[	[	X
fnp-5809	32	2	grassl	grassl	VERB
fnp-5809	32	3	et	et	PROPN
fnp-5809	32	4	al	al	PROPN
fnp-5809	32	5	.	.	PROPN
fnp-5809	32	6	,	,	PUNCT
fnp-5809	32	7	2023	2023	NUM
fnp-5809	32	8	]	]	PUNCT
fnp-5809	32	9	.	.	PUNCT
fnp-5809	33	1	clinical	clinical	ADJ
fnp-5809	33	2	study	study	NOUN
fnp-5809	33	3	in	in	ADP
fnp-5809	33	4	patients	patient	NOUN
fnp-5809	33	5	with	with	ADP
fnp-5809	33	6	idh	idh	NOUN
fnp-5809	33	7	mutant	mutant	ADJ
fnp-5809	33	8	low	low	ADJ
fnp-5809	33	9	-	-	PUNCT
fnp-5809	33	10	grade	grade	NOUN
fnp-5809	33	11	glioma	glioma	NOUN
fnp-5809	33	12	using	use	VERB
fnp-5809	33	13	an	an	DET
fnp-5809	33	14	oral	oral	ADJ
fnp-5809	33	15	,	,	PUNCT
fnp-5809	33	16	brain	brain	NOUN
fnp-5809	33	17	-	-	PUNCT
fnp-5809	33	18	penetrant	penetrant	NOUN
fnp-5809	33	19	inhibitor	inhibitor	NOUN
fnp-5809	33	20	of	of	ADP
fnp-5809	33	21	mutant	mutant	ADJ
fnp-5809	33	22	idh1	idh1	PROPN
fnp-5809	33	23	and	and	CCONJ
fnp-5809	33	24	idh2	idh2	PROPN
fnp-5809	33	25	enzymes	enzyme	NOUN
fnp-5809	34	1	[	[	X
fnp-5809	34	2	mellinghoff	mellinghoff	X
fnp-5809	34	3	et	et	PROPN
fnp-5809	34	4	al	al	PROPN
fnp-5809	34	5	.	.	PROPN
fnp-5809	34	6	,	,	PUNCT
fnp-5809	34	7	2023	2023	NUM
fnp-5809	34	8	]	]	PUNCT
fnp-5809	34	9	.	.	PUNCT
fnp-5809	35	1	interdisciplinary	interdisciplinary	ADJ
fnp-5809	35	2	discussions	discussion	NOUN
fnp-5809	35	3	are	be	AUX
fnp-5809	35	4	important	important	ADJ
fnp-5809	35	5	as	as	ADP
fnp-5809	35	6	the	the	DET
fnp-5809	35	7	key	key	ADJ
fnp-5809	35	8	role	role	NOUN
fnp-5809	35	9	of	of	ADP
fnp-5809	35	10	neuropathological	neuropathological	ADJ
fnp-5809	35	11	shifts	shift	NOUN
fnp-5809	35	12	from	from	ADP
fnp-5809	35	13	being	be	AUX
fnp-5809	35	14	purely	purely	ADV
fnp-5809	35	15	diagnostic	diagnostic	ADJ
fnp-5809	35	16	to	to	PART
fnp-5809	35	17	prognostic	prognostic	VERB
fnp-5809	35	18	to	to	ADP
fnp-5809	35	19	more	more	ADV
fnp-5809	35	20	and	and	CCONJ
fnp-5809	35	21	more	more	ADV
fnp-5809	35	22	theranostic	theranostic	ADJ
fnp-5809	35	23	.	.	PUNCT
fnp-5809	36	1	an	an	DET
fnp-5809	36	2	increased	increase	VERB
fnp-5809	36	3	number	number	NOUN
fnp-5809	36	4	of	of	ADP
fnp-5809	36	5	neurooncological	neurooncological	ADJ
fnp-5809	36	6	patients	patient	NOUN
fnp-5809	36	7	are	be	AUX
fnp-5809	36	8	currently	currently	ADV
fnp-5809	36	9	treated	treat	VERB
fnp-5809	36	10	based	base	VERB
fnp-5809	36	11	on	on	ADP
fnp-5809	36	12	biomarker	biomarker	NOUN
fnp-5809	36	13	-	-	PUNCT
fnp-5809	36	14	guided	guide	VERB
fnp-5809	36	15	decisions	decision	NOUN
fnp-5809	36	16	jointly	jointly	ADV
fnp-5809	36	17	made	make	VERB
fnp-5809	36	18	in	in	ADP
fnp-5809	36	19	multidisciplinary	multidisciplinary	ADJ
fnp-5809	36	20	molecular	molecular	ADJ
fnp-5809	36	21	tumor	tumor	NOUN
fnp-5809	36	22	boards	board	NOUN
fnp-5809	36	23	[	[	X
fnp-5809	36	24	renovanz	renovanz	VERB
fnp-5809	36	25	et	et	PROPN
fnp-5809	36	26	al	al	PROPN
fnp-5809	36	27	.	.	PROPN
fnp-5809	36	28	,	,	PUNCT
fnp-5809	36	29	2023	2023	NUM
fnp-5809	36	30	]	]	PUNCT
fnp-5809	36	31	.	.	PUNCT
fnp-5809	37	1	as	as	ADP
fnp-5809	37	2	in	in	ADP
fnp-5809	37	3	many	many	ADJ
fnp-5809	37	4	neurooncological	neurooncological	ADJ
fnp-5809	37	5	centers	center	NOUN
fnp-5809	37	6	the	the	DET
fnp-5809	37	7	immunohistochemical	immunohistochemical	ADJ
fnp-5809	37	8	,	,	PUNCT
fnp-5809	37	9	dna	dna	PROPN
fnp-5809	37	10	/	/	SYM
fnp-5809	37	11	rna	rna	NOUN
fnp-5809	37	12	in	in	ADP
fnp-5809	37	13	-	-	PUNCT
fnp-5809	37	14	situ	situ	NOUN
fnp-5809	37	15	,	,	PUNCT
fnp-5809	37	16	genetic	genetic	ADJ
fnp-5809	37	17	and/or	and/or	CCONJ
fnp-5809	37	18	epigenetic	epigenetic	ADJ
fnp-5809	37	19	biomarker	biomarker	NOUN
fnp-5809	37	20	analyses	analysis	NOUN
fnp-5809	37	21	are	be	AUX
fnp-5809	37	22	performed	perform	VERB
fnp-5809	37	23	by	by	ADP
fnp-5809	37	24	neuropathologists	neuropathologist	NOUN
fnp-5809	37	25	,	,	PUNCT
fnp-5809	37	26	it	it	PRON
fnp-5809	37	27	is	be	AUX
fnp-5809	37	28	imperative	imperative	ADJ
fnp-5809	37	29	that	that	SCONJ
fnp-5809	37	30	neuropathologists	neuropathologist	NOUN
fnp-5809	37	31	help	help	VERB
fnp-5809	37	32	to	to	PART
fnp-5809	37	33	rapidly	rapidly	ADV
fnp-5809	37	34	translate	translate	VERB
fnp-5809	37	35	unequivocal	unequivocal	ADJ
fnp-5809	37	36	findings	finding	NOUN
fnp-5809	37	37	from	from	ADP
fnp-5809	37	38	both	both	DET
fnp-5809	37	39	basic	basic	ADJ
fnp-5809	37	40	tumor	tumor	NOUN
fnp-5809	37	41	biological	biological	ADJ
fnp-5809	37	42	and	and	CCONJ
fnp-5809	37	43	clinico	clinico	NOUN
fnp-5809	37	44	-	-	PUNCT
fnp-5809	37	45	oncological	oncological	ADJ
fnp-5809	37	46	studies	study	NOUN
fnp-5809	37	47	into	into	ADP
fnp-5809	37	48	diagnostic	diagnostic	ADJ
fnp-5809	37	49	or	or	CCONJ
fnp-5809	37	50	theranostic	theranostic	ADJ
fnp-5809	37	51	tests	test	NOUN
fnp-5809	37	52	to	to	PART
fnp-5809	37	53	facilitate	facilitate	VERB
fnp-5809	37	54	improved	improve	VERB
fnp-5809	37	55	patient	patient	ADJ
fnp-5809	37	56	care	care	NOUN
fnp-5809	37	57	.	.	PUNCT
fnp-5809	38	1	the	the	DET
fnp-5809	38	2	author	author	NOUN
fnp-5809	38	3	strongly	strongly	ADV
fnp-5809	38	4	hopes	hope	VERB
fnp-5809	38	5	that	that	SCONJ
fnp-5809	38	6	the	the	DET
fnp-5809	38	7	selected	select	VERB
fnp-5809	38	8	papers	paper	NOUN
fnp-5809	38	9	will	will	AUX
fnp-5809	38	10	both	both	PRON
fnp-5809	38	11	fascinate	fascinate	VERB
fnp-5809	38	12	the	the	DET
fnp-5809	38	13	readers	reader	NOUN
fnp-5809	38	14	and	and	CCONJ
fnp-5809	38	15	further	far	ADV
fnp-5809	38	16	stimulate	stimulate	VERB
fnp-5809	38	17	discussions	discussion	NOUN
fnp-5809	38	18	around	around	ADP
fnp-5809	38	19	neurooncological	neurooncological	ADJ
fnp-5809	38	20	topics	topic	NOUN
fnp-5809	38	21	in	in	ADP
fnp-5809	38	22	neuropathology	neuropathology	NOUN
fnp-5809	38	23	.	.	PUNCT
fnp-5809	39	1	1	1	X
fnp-5809	39	2	.	.	X
fnp-5809	39	3	frequency	frequency	NOUN
fnp-5809	39	4	-	-	PUNCT
fnp-5809	39	5	dependent	dependent	ADJ
fnp-5809	39	6	mapk	mapk	NOUN
fnp-5809	39	7	and	and	CCONJ
fnp-5809	39	8	nfkb	nfkb	PROPN
fnp-5809	39	9	pathway	pathway	NOUN
fnp-5809	39	10	-	-	PUNCT
fnp-5809	39	11	activation	activation	NOUN
fnp-5809	39	12	by	by	ADP
fnp-5809	39	13	rhythmic	rhythmic	ADJ
fnp-5809	39	14	ca2	ca2	PROPN
fnp-5809	39	15	+	+	PROPN
fnp-5809	39	16	oscillations	oscillation	NOUN
fnp-5809	39	17	as	as	ADP
fnp-5809	39	18	potential	potential	ADJ
fnp-5809	39	19	treatment	treatment	NOUN
fnp-5809	39	20	target	target	NOUN
fnp-5809	39	21	in	in	ADP
fnp-5809	39	22	glioma	glioma	NOUN
fnp-5809	39	23	[	[	X
fnp-5809	39	24	hausmann	hausmann	PROPN
fnp-5809	39	25	et	et	PROPN
fnp-5809	39	26	al	al	PROPN
fnp-5809	39	27	.	.	PROPN
fnp-5809	39	28	,	,	PUNCT
fnp-5809	39	29	2023	2023	NUM
fnp-5809	39	30	]	]	PUNCT
fnp-5809	39	31	.	.	PUNCT
fnp-5809	40	1	it	it	PRON
fnp-5809	40	2	has	have	AUX
fnp-5809	40	3	been	be	AUX
fnp-5809	40	4	previously	previously	ADV
fnp-5809	40	5	reported	report	VERB
fnp-5809	40	6	that	that	SCONJ
fnp-5809	40	7	glioma	glioma	NOUN
fnp-5809	40	8	cells	cell	NOUN
fnp-5809	40	9	are	be	AUX
fnp-5809	40	10	not	not	PART
fnp-5809	40	11	only	only	ADV
fnp-5809	40	12	interconnected	interconnect	VERB
fnp-5809	40	13	between	between	ADP
fnp-5809	40	14	each	each	DET
fnp-5809	40	15	other	other	ADJ
fnp-5809	40	16	but	but	CCONJ
fnp-5809	40	17	also	also	ADV
fnp-5809	40	18	to	to	ADP
fnp-5809	40	19	neurons	neuron	NOUN
fnp-5809	40	20	via	via	ADP
fnp-5809	40	21	microtubes	microtube	NOUN
fnp-5809	40	22	enabling	enable	VERB
fnp-5809	40	23	intercellular	intercellular	ADJ
fnp-5809	40	24	communication	communication	NOUN
fnp-5809	40	25	via	via	ADP
fnp-5809	40	26	calcium	calcium	NOUN
fnp-5809	40	27	signaling	signal	VERB
fnp-5809	40	28	[	[	X
fnp-5809	40	29	venkataramani	venkataramani	NOUN
fnp-5809	40	30	et	et	PROPN
fnp-5809	40	31	al	al	PROPN
fnp-5809	40	32	.	.	PROPN
fnp-5809	40	33	,	,	PUNCT
fnp-5809	40	34	2019	2019	NUM
fnp-5809	40	35	]	]	PUNCT
fnp-5809	40	36	.	.	PUNCT
fnp-5809	41	1	calcium	calcium	NOUN
fnp-5809	41	2	signaling	signal	VERB
fnp-5809	41	3	induced	induce	VERB
fnp-5809	41	4	by	by	ADP
fnp-5809	41	5	neuronal	neuronal	ADJ
fnp-5809	41	6	activity	activity	NOUN
fnp-5809	41	7	increased	increase	VERB
fnp-5809	41	8	the	the	DET
fnp-5809	41	9	formation	formation	NOUN
fnp-5809	41	10	of	of	ADP
fnp-5809	41	11	glioma	glioma	NOUN
fnp-5809	41	12	microtubes	microtube	NOUN
fnp-5809	41	13	and	and	CCONJ
fnp-5809	41	14	cell	cell	NOUN
fnp-5809	41	15	invasion	invasion	NOUN
fnp-5809	41	16	[	[	X
fnp-5809	41	17	venkataramani	venkataramani	X
fnp-5809	41	18	et	et	PROPN
fnp-5809	41	19	al	al	PROPN
fnp-5809	41	20	.	.	PROPN
fnp-5809	41	21	,	,	PUNCT
fnp-5809	41	22	2022	2022	NUM
fnp-5809	41	23	]	]	PUNCT
fnp-5809	41	24	.	.	PUNCT
fnp-5809	42	1	however	however	ADV
fnp-5809	42	2	,	,	PUNCT
fnp-5809	42	3	the	the	DET
fnp-5809	42	4	exact	exact	ADJ
fnp-5809	42	5	mechanisms	mechanism	NOUN
fnp-5809	42	6	how	how	SCONJ
fnp-5809	42	7	the	the	DET
fnp-5809	42	8	intercellular	intercellular	ADJ
fnp-5809	42	9	communication	communication	NOUN
fnp-5809	42	10	between	between	ADP
fnp-5809	42	11	neurons	neuron	NOUN
fnp-5809	42	12	and	and	CCONJ
fnp-5809	42	13	glioma	glioma	NOUN
fnp-5809	42	14	cells	cell	NOUN
fnp-5809	42	15	or	or	CCONJ
fnp-5809	42	16	uniquely	uniquely	ADV
fnp-5809	42	17	amongst	amongst	ADP
fnp-5809	42	18	glioma	glioma	NOUN
fnp-5809	42	19	cells	cell	NOUN
fnp-5809	42	20	were	be	AUX
fnp-5809	42	21	still	still	ADV
fnp-5809	42	22	not	not	PART
fnp-5809	42	23	fully	fully	ADV
fnp-5809	42	24	deciphered	decipher	VERB
fnp-5809	42	25	.	.	PUNCT
fnp-5809	43	1	in	in	ADP
fnp-5809	43	2	the	the	DET
fnp-5809	43	3	present	present	ADJ
fnp-5809	43	4	study	study	NOUN
fnp-5809	43	5	,	,	PUNCT
fnp-5809	43	6	hausmann	hausmann	PROPN
fnp-5809	43	7	et	et	PROPN
fnp-5809	43	8	al	al	PROPN
fnp-5809	43	9	.	.	PROPN
fnp-5809	43	10	showed	show	VERB
fnp-5809	43	11	that	that	SCONJ
fnp-5809	43	12	a	a	DET
fnp-5809	43	13	minor	minor	ADJ
fnp-5809	43	14	glioma	glioma	NOUN
fnp-5809	43	15	cell	cell	NOUN
fnp-5809	43	16	fraction	fraction	NOUN
fnp-5809	43	17	,	,	PUNCT
fnp-5809	43	18	accounting	account	VERB
fnp-5809	43	19	for	for	ADP
fnp-5809	43	20	only	only	ADV
fnp-5809	43	21	1–5	1–5	NUM
fnp-5809	43	22	 	 	SPACE
fnp-5809	43	23	%	%	NOUN
fnp-5809	43	24	of	of	ADP
fnp-5809	43	25	all	all	DET
fnp-5809	43	26	tumor	tumor	NOUN
fnp-5809	43	27	cells	cell	NOUN
fnp-5809	43	28	is	be	AUX
fnp-5809	43	29	able	able	ADJ
fnp-5809	43	30	to	to	PART
fnp-5809	43	31	rhythmically	rhythmically	VERB
fnp-5809	43	32	trigger	trigger	VERB
fnp-5809	43	33	ca2	ca2	PROPN
fnp-5809	43	34	+	+	PROPN
fnp-5809	43	35	oscillations	oscillation	NOUN
fnp-5809	44	1	[	[	X
fnp-5809	44	2	hausmann	hausmann	PROPN
fnp-5809	44	3	et	et	PROPN
fnp-5809	44	4	al	al	PROPN
fnp-5809	44	5	.	.	PROPN
fnp-5809	44	6	,	,	PUNCT
fnp-5809	44	7	2023	2023	NUM
fnp-5809	44	8	]	]	PUNCT
fnp-5809	44	9	.	.	PUNCT
fnp-5809	45	1	those	those	DET
fnp-5809	45	2	cells	cell	NOUN
fnp-5809	45	3	belong	belong	VERB
fnp-5809	45	4	to	to	ADP
fnp-5809	45	5	the	the	DET
fnp-5809	45	6	cellular	cellular	ADJ
fnp-5809	45	7	fraction	fraction	NOUN
fnp-5809	45	8	showing	show	VERB
fnp-5809	45	9	a	a	DET
fnp-5809	45	10	considerably	considerably	ADV
fnp-5809	45	11	higher	high	ADJ
fnp-5809	45	12	number	number	NOUN
fnp-5809	45	13	of	of	ADP
fnp-5809	45	14	tumor	tumor	NOUN
fnp-5809	45	15	microtube	microtube	NOUN
fnp-5809	45	16	connections	connection	NOUN
fnp-5809	45	17	to	to	ADP
fnp-5809	45	18	other	other	ADJ
fnp-5809	45	19	glioma	glioma	NOUN
fnp-5809	45	20	cells	cell	NOUN
fnp-5809	45	21	.	.	PUNCT
fnp-5809	46	1	as	as	SCONJ
fnp-5809	46	2	the	the	DET
fnp-5809	46	3	ca2	ca2	PROPN
fnp-5809	46	4	+	+	PROPN
fnp-5809	46	5	oscillations	oscillation	NOUN
fnp-5809	46	6	in	in	ADP
fnp-5809	46	7	glioma	glioma	NOUN
fnp-5809	46	8	cells	cell	NOUN
fnp-5809	46	9	were	be	AUX
fnp-5809	46	10	not	not	PART
fnp-5809	46	11	only	only	ADV
fnp-5809	46	12	observed	observe	VERB
fnp-5809	46	13	in	in	ADP
fnp-5809	46	14	vivo	vivo	NOUN
fnp-5809	46	15	in	in	ADP
fnp-5809	46	16	the	the	DET
fnp-5809	46	17	presence	presence	NOUN
fnp-5809	46	18	of	of	ADP
fnp-5809	46	19	neurons	neuron	NOUN
fnp-5809	46	20	but	but	CCONJ
fnp-5809	46	21	also	also	ADV
fnp-5809	46	22	in	in	ADP
fnp-5809	46	23	neuron	neuron	NOUN
fnp-5809	46	24	-	-	PUNCT
fnp-5809	46	25	free	free	ADJ
fnp-5809	46	26	cell	cell	NOUN
fnp-5809	46	27	culture	culture	NOUN
fnp-5809	46	28	conditions	condition	NOUN
fnp-5809	46	29	,	,	PUNCT
fnp-5809	46	30	one	one	PRON
fnp-5809	46	31	can	can	AUX
fnp-5809	46	32	assume	assume	VERB
fnp-5809	46	33	that	that	SCONJ
fnp-5809	46	34	this	this	DET
fnp-5809	46	35	periodic	periodic	ADJ
fnp-5809	46	36	activity	activity	NOUN
fnp-5809	46	37	is	be	AUX
fnp-5809	46	38	a	a	DET
fnp-5809	46	39	glioma	glioma	NOUN
fnp-5809	46	40	-	-	PUNCT
fnp-5809	46	41	cell	cell	NOUN
fnp-5809	46	42	autonomous	autonomous	ADJ
fnp-5809	46	43	mechanism	mechanism	NOUN
fnp-5809	46	44	.	.	PUNCT
fnp-5809	47	1	this	this	DET
fnp-5809	47	2	hypothesis	hypothesis	NOUN
fnp-5809	47	3	was	be	AUX
fnp-5809	47	4	further	far	ADV
fnp-5809	47	5	corroborated	corroborate	VERB
fnp-5809	47	6	by	by	ADP
fnp-5809	47	7	the	the	DET
fnp-5809	47	8	finding	finding	NOUN
fnp-5809	47	9	that	that	SCONJ
fnp-5809	47	10	blocking	block	VERB
fnp-5809	47	11	gap	gap	NOUN
fnp-5809	47	12	junction	junction	NOUN
fnp-5809	47	13	and/or	and/or	CCONJ
fnp-5809	47	14	tumor	tumor	NOUN
fnp-5809	47	15	microtube	microtube	NOUN
fnp-5809	47	16	formation	formation	NOUN
fnp-5809	47	17	did	do	AUX
fnp-5809	47	18	not	not	PART
fnp-5809	47	19	reduce	reduce	VERB
fnp-5809	47	20	the	the	DET
fnp-5809	47	21	periodic	periodic	ADJ
fnp-5809	47	22	ca2	ca2	PROPN
fnp-5809	47	23	+	+	NOUN
fnp-5809	47	24	activity	activity	NOUN
fnp-5809	47	25	in	in	ADP
fnp-5809	47	26	this	this	DET
fnp-5809	47	27	small	small	ADJ
fnp-5809	47	28	glioma	glioma	NOUN
fnp-5809	47	29	subpopulation	subpopulation	NOUN
fnp-5809	47	30	,	,	PUNCT
fnp-5809	47	31	but	but	CCONJ
fnp-5809	47	32	considerably	considerably	ADV
fnp-5809	47	33	reduced	reduce	VERB
fnp-5809	47	34	the	the	DET
fnp-5809	47	35	related	relate	VERB
fnp-5809	47	36	ca2	ca2	PROPN
fnp-5809	47	37	+	+	NOUN
fnp-5809	47	38	activity	activity	NOUN
fnp-5809	47	39	in	in	ADP
fnp-5809	47	40	the	the	DET
fnp-5809	47	41	intertumoral	intertumoral	ADJ
fnp-5809	47	42	network	network	NOUN
fnp-5809	47	43	.	.	PUNCT
fnp-5809	48	1	a	a	DET
fnp-5809	48	2	pharmacological	pharmacological	ADJ
fnp-5809	48	3	screen	screen	NOUN
fnp-5809	48	4	revealed	reveal	VERB
fnp-5809	48	5	that	that	SCONJ
fnp-5809	48	6	specific	specific	ADJ
fnp-5809	48	7	inhibition	inhibition	NOUN
fnp-5809	48	8	of	of	ADP
fnp-5809	48	9	the	the	DET
fnp-5809	48	10	calcium	calcium	NOUN
fnp-5809	48	11	-	-	PUNCT
fnp-5809	48	12	activated	activate	VERB
fnp-5809	48	13	potassium	potassium	NOUN
fnp-5809	48	14	channel	channel	NOUN
fnp-5809	48	15	kca3.1	kca3.1	PROPN
fnp-5809	48	16	reduced	reduce	VERB
fnp-5809	48	17	ca2	ca2	PROPN
fnp-5809	48	18	+	+	PROPN
fnp-5809	48	19	activity	activity	NOUN
fnp-5809	48	20	also	also	ADV
fnp-5809	48	21	in	in	ADP
fnp-5809	48	22	those	those	DET
fnp-5809	48	23	glioma	glioma	NOUN
fnp-5809	48	24	cells	cell	NOUN
fnp-5809	48	25	.	.	PUNCT
fnp-5809	49	1	the	the	DET
fnp-5809	49	2	respective	respective	ADJ
fnp-5809	49	3	potassium	potassium	NOUN
fnp-5809	49	4	channel	channel	NOUN
fnp-5809	49	5	appears	appear	VERB
fnp-5809	49	6	to	to	PART
fnp-5809	49	7	be	be	AUX
fnp-5809	49	8	of	of	ADP
fnp-5809	49	9	interest	interest	NOUN
fnp-5809	49	10	in	in	ADP
fnp-5809	49	11	glioma	glioma	NOUN
fnp-5809	49	12	biology	biology	NOUN
fnp-5809	49	13	as	as	SCONJ
fnp-5809	49	14	implications	implication	NOUN
fnp-5809	49	15	for	for	ADP
fnp-5809	49	16	enhanced	enhanced	ADJ
fnp-5809	49	17	malignant	malignant	ADJ
fnp-5809	49	18	behavior	behavior	NOUN
fnp-5809	49	19	,	,	PUNCT
fnp-5809	49	20	in	in	ADP
fnp-5809	49	21	particular	particular	ADJ
fnp-5809	49	22	enhanced	enhanced	ADJ
fnp-5809	49	23	glioma	glioma	NOUN
fnp-5809	49	24	cell	cell	NOUN
fnp-5809	49	25	invasion	invasion	NOUN
fnp-5809	49	26	in	in	ADP
fnp-5809	49	27	the	the	DET
fnp-5809	49	28	presence	presence	NOUN
fnp-5809	49	29	of	of	ADP
fnp-5809	49	30	kca3.1	kca3.1	PROPN
fnp-5809	49	31	,	,	PUNCT
fnp-5809	49	32	have	have	AUX
fnp-5809	49	33	been	be	AUX
fnp-5809	49	34	reported	report	VERB
fnp-5809	49	35	[	[	PUNCT
fnp-5809	49	36	d'alessandro	d'alessandro	X
fnp-5809	49	37	et	et	NOUN
fnp-5809	49	38	al	al	PROPN
fnp-5809	49	39	.	.	PROPN
fnp-5809	49	40	,	,	PUNCT
fnp-5809	49	41	2013	2013	NUM
fnp-5809	49	42	;	;	PUNCT
fnp-5809	49	43	turner	turner	PROPN
fnp-5809	49	44	et	et	PROPN
fnp-5809	49	45	al	al	PROPN
fnp-5809	49	46	.	.	PROPN
fnp-5809	49	47	,	,	PUNCT
fnp-5809	49	48	2014	2014	NUM
fnp-5809	49	49	]	]	PUNCT
fnp-5809	49	50	.	.	PUNCT
fnp-5809	50	1	kca3.1	kca3.1	ADJ
fnp-5809	50	2	-	-	PUNCT
fnp-5809	50	3	positive	positive	ADJ
fnp-5809	50	4	cells	cell	NOUN
fnp-5809	50	5	rhythmically	rhythmically	ADV
fnp-5809	50	6	stimulated	stimulate	VERB
fnp-5809	50	7	ca2	ca2	PROPN
fnp-5809	50	8	+	+	PROPN
fnp-5809	50	9	signaling	signal	VERB
fnp-5809	50	10	at	at	ADP
fnp-5809	50	11	a	a	DET
fnp-5809	50	12	mean	mean	ADJ
fnp-5809	50	13	frequency	frequency	NOUN
fnp-5809	50	14	of	of	ADP
fnp-5809	50	15	12.5–12.7	12.5–12.7	NUM
fnp-5809	50	16	mhz	mhz	NOUN
fnp-5809	50	17	(	(	PUNCT
fnp-5809	50	18	in	in	ADP
fnp-5809	50	19	vivo	vivo	NOUN
fnp-5809	50	20	)	)	PUNCT
fnp-5809	50	21	and	and	CCONJ
fnp-5809	50	22	9.7–11.3	9.7–11.3	NUM
fnp-5809	50	23	mhz	mhz	NOUN
fnp-5809	50	24	(	(	PUNCT
fnp-5809	50	25	in	in	ADP
fnp-5809	50	26	vitro	vitro	X
fnp-5809	50	27	)	)	PUNCT
fnp-5809	50	28	within	within	ADP
fnp-5809	50	29	the	the	DET
fnp-5809	50	30	glioma	glioma	NOUN
fnp-5809	50	31	network	network	NOUN
fnp-5809	50	32	,	,	PUNCT
fnp-5809	50	33	apparently	apparently	ADV
fnp-5809	50	34	a	a	DET
fnp-5809	50	35	range	range	NOUN
fnp-5809	50	36	in	in	ADP
fnp-5809	50	37	which	which	PRON
fnp-5809	50	38	also	also	ADV
fnp-5809	50	39	the	the	DET
fnp-5809	50	40	mapk	mapk	NOUN
fnp-5809	50	41	and	and	CCONJ
fnp-5809	50	42	nfkb	nfkb	PROPN
fnp-5809	50	43	pathways	pathway	NOUN
fnp-5809	50	44	increase	increase	VERB
fnp-5809	50	45	cell	cell	NOUN
fnp-5809	50	46	proliferation	proliferation	NOUN
fnp-5809	50	47	and	and	CCONJ
fnp-5809	50	48	survival	survival	NOUN
fnp-5809	50	49	.	.	PUNCT
fnp-5809	51	1	along	along	ADP
fnp-5809	51	2	this	this	DET
fnp-5809	51	3	line	line	NOUN
fnp-5809	51	4	,	,	PUNCT
fnp-5809	51	5	the	the	DET
fnp-5809	51	6	inhibition	inhibition	NOUN
fnp-5809	51	7	or	or	CCONJ
fnp-5809	51	8	knockout	knockout	NOUN
fnp-5809	51	9	of	of	ADP
fnp-5809	51	10	kca3.1	kca3.1	PROPN
fnp-5809	51	11	led	lead	VERB
fnp-5809	51	12	to	to	ADP
fnp-5809	51	13	reduced	reduce	VERB
fnp-5809	51	14	mapk	mapk	NOUN
fnp-5809	51	15	and	and	CCONJ
fnp-5809	51	16	nfkb	nfkb	PROPN
fnp-5809	51	17	pathway	pathway	NOUN
fnp-5809	51	18	activity	activity	NOUN
fnp-5809	51	19	while	while	SCONJ
fnp-5809	51	20	its	its	PRON
fnp-5809	51	21	stimulation	stimulation	NOUN
fnp-5809	51	22	enhanced	enhance	VERB
fnp-5809	51	23	the	the	DET
fnp-5809	51	24	activity	activity	NOUN
fnp-5809	51	25	of	of	ADP
fnp-5809	51	26	both	both	DET
fnp-5809	51	27	pathways	pathway	NOUN
fnp-5809	51	28	.	.	PUNCT
fnp-5809	52	1	the	the	DET
fnp-5809	52	2	knockdown	knockdown	NOUN
fnp-5809	52	3	of	of	ADP
fnp-5809	52	4	kca3.1	kca3.1	PROPN
fnp-5809	52	5	was	be	AUX
fnp-5809	52	6	associated	associate	VERB
fnp-5809	52	7	with	with	ADP
fnp-5809	52	8	significantly	significantly	ADV
fnp-5809	52	9	reduced	reduce	VERB
fnp-5809	52	10	glioma	glioma	NOUN
fnp-5809	52	11	growth	growth	NOUN
fnp-5809	52	12	in	in	ADP
fnp-5809	52	13	animal	animal	NOUN
fnp-5809	52	14	models	model	NOUN
fnp-5809	52	15	and	and	CCONJ
fnp-5809	52	16	survival	survival	NOUN
fnp-5809	52	17	analyses	analysis	NOUN
fnp-5809	52	18	of	of	ADP
fnp-5809	52	19	an	an	DET
fnp-5809	52	20	openly	openly	ADV
fnp-5809	52	21	accessible	accessible	ADJ
fnp-5809	52	22	patient	patient	ADJ
fnp-5809	52	23	cohort	cohort	NOUN
fnp-5809	52	24	(	(	PUNCT
fnp-5809	52	25	the	the	DET
fnp-5809	52	26	cancer	cancer	NOUN
fnp-5809	52	27	genome	genome	NOUN
fnp-5809	52	28	atlas	atlas	PROPN
fnp-5809	52	29	tcga	tcga	PROPN
fnp-5809	52	30	)	)	PUNCT
fnp-5809	52	31	revealed	reveal	VERB
fnp-5809	52	32	that	that	SCONJ
fnp-5809	52	33	glioblastoma	glioblastoma	NOUN
fnp-5809	52	34	patients	patient	NOUN
fnp-5809	52	35	with	with	ADP
fnp-5809	52	36	high	high	ADJ
fnp-5809	52	37	kca3.1	kca3.1	PROPN
fnp-5809	52	38	expression	expression	NOUN
fnp-5809	52	39	showed	show	VERB
fnp-5809	52	40	significantly	significantly	ADV
fnp-5809	52	41	worse	bad	ADJ
fnp-5809	52	42	survival	survival	NOUN
fnp-5809	52	43	as	as	SCONJ
fnp-5809	52	44	compared	compare	VERB
fnp-5809	52	45	to	to	ADP
fnp-5809	52	46	their	their	PRON
fnp-5809	52	47	counterpart	counterpart	NOUN
fnp-5809	52	48	with	with	ADP
fnp-5809	52	49	low	low	ADJ
fnp-5809	52	50	kca3.1	kca3.1	PROPN
fnp-5809	52	51	expression	expression	NOUN
fnp-5809	52	52	.	.	PUNCT
fnp-5809	53	1	in	in	ADP
fnp-5809	53	2	summary	summary	NOUN
fnp-5809	53	3	,	,	PUNCT
fnp-5809	53	4	those	those	DET
fnp-5809	53	5	findings	finding	NOUN
fnp-5809	53	6	point	point	VERB
fnp-5809	53	7	to	to	ADP
fnp-5809	53	8	a	a	DET
fnp-5809	53	9	new	new	ADJ
fnp-5809	53	10	treatment	treatment	NOUN
fnp-5809	53	11	option	option	NOUN
fnp-5809	53	12	for	for	ADP
fnp-5809	53	13	glioblastoma	glioblastoma	NOUN
fnp-5809	53	14	patients	patient	NOUN
fnp-5809	53	15	by	by	ADP
fnp-5809	53	16	targeting	target	VERB
fnp-5809	53	17	more	more	ADV
fnp-5809	53	18	specifically	specifically	ADV
fnp-5809	53	19	kca3.1	kca3.1	PROPN
fnp-5809	53	20	thereby	thereby	ADV
fnp-5809	53	21	focusing	focus	VERB
fnp-5809	53	22	on	on	ADP
fnp-5809	53	23	the	the	DET
fnp-5809	53	24	cell	cell	NOUN
fnp-5809	53	25	population	population	NOUN
fnp-5809	53	26	that	that	PRON
fnp-5809	53	27	seems	seem	VERB
fnp-5809	53	28	to	to	PART
fnp-5809	53	29	negatively	negatively	ADV
fnp-5809	53	30	orchestrate	orchestrate	VERB
fnp-5809	53	31	the	the	DET
fnp-5809	53	32	glioma	glioma	NOUN
fnp-5809	53	33	cell	cell	NOUN
fnp-5809	53	34	network	network	NOUN
fnp-5809	53	35	.	.	PUNCT
fnp-5809	54	1	although	although	SCONJ
fnp-5809	54	2	it	it	PRON
fnp-5809	54	3	was	be	AUX
fnp-5809	54	4	demonstrated	demonstrate	VERB
fnp-5809	54	5	that	that	SCONJ
fnp-5809	54	6	the	the	DET
fnp-5809	54	7	cell	cell	NOUN
fnp-5809	54	8	state	state	NOUN
fnp-5809	54	9	of	of	ADP
fnp-5809	54	10	rhythmically	rhythmically	NOUN
fnp-5809	54	11	performing	perform	VERB
fnp-5809	54	12	ca2	ca2	PROPN
fnp-5809	54	13	+	+	NOUN
fnp-5809	54	14	signaling	signal	VERB
fnp-5809	54	15	is	be	AUX
fnp-5809	54	16	hierarchical	hierarchical	ADJ
fnp-5809	54	17	,	,	PUNCT
fnp-5809	54	18	but	but	CCONJ
fnp-5809	54	19	highly	highly	ADV
fnp-5809	54	20	plastic	plastic	ADJ
fnp-5809	54	21	,	,	PUNCT
fnp-5809	54	22	it	it	PRON
fnp-5809	54	23	still	still	ADV
fnp-5809	54	24	remains	remain	VERB
fnp-5809	54	25	to	to	PART
fnp-5809	54	26	be	be	AUX
fnp-5809	54	27	determined	determine	VERB
fnp-5809	54	28	why	why	SCONJ
fnp-5809	54	29	only	only	ADV
fnp-5809	54	30	a	a	DET
fnp-5809	54	31	very	very	ADV
fnp-5809	54	32	small	small	ADJ
fnp-5809	54	33	subpopulation	subpopulation	NOUN
fnp-5809	54	34	of	of	ADP
fnp-5809	54	35	glioma	glioma	NOUN
fnp-5809	54	36	cells	cell	NOUN
fnp-5809	54	37	acquire	acquire	VERB
fnp-5809	54	38	this	this	DET
fnp-5809	54	39	state	state	NOUN
fnp-5809	54	40	at	at	ADP
fnp-5809	54	41	any	any	DET
fnp-5809	54	42	given	give	VERB
fnp-5809	54	43	time	time	NOUN
fnp-5809	54	44	(	(	PUNCT
fnp-5809	54	45	summary	summary	NOUN
fnp-5809	54	46	of	of	ADP
fnp-5809	54	47	the	the	DET
fnp-5809	54	48	proposed	propose	VERB
fnp-5809	54	49	mechanism	mechanism	NOUN
fnp-5809	54	50	in	in	ADP
fnp-5809	54	51	figure	figure	NOUN
fnp-5809	54	52	1	1	NUM
fnp-5809	54	53	)	)	PUNCT
fnp-5809	54	54	.	.	PUNCT
fnp-5809	55	1	figure	figure	VERB
fnp-5809	55	2	1	1	NUM
fnp-5809	55	3	:	:	PUNCT
fnp-5809	55	4	rhythmic	rhythmic	ADJ
fnp-5809	55	5	ca2	ca2	PROPN
fnp-5809	55	6	+	+	CCONJ
fnp-5809	55	7	oscillation	oscillation	NOUN
fnp-5809	55	8	mechanism	mechanism	NOUN
fnp-5809	55	9	in	in	ADP
fnp-5809	55	10	glioma	glioma	NOUN
fnp-5809	55	11	cell	cell	NOUN
fnp-5809	55	12	networks	network	NOUN
fnp-5809	55	13	leading	lead	VERB
fnp-5809	55	14	to	to	ADP
fnp-5809	55	15	enhanced	enhance	VERB
fnp-5809	55	16	malignancy	malignancy	NOUN
fnp-5809	55	17	via	via	ADP
fnp-5809	55	18	nf	nf	PROPN
fnp-5809	55	19	-	-	PUNCT
fnp-5809	55	20	kb	kb	NOUN
fnp-5809	55	21	and	and	CCONJ
fnp-5809	55	22	mapk	mapk	NOUN
fnp-5809	55	23	pathway	pathway	NOUN
fnp-5809	55	24	activation	activation	NOUN
fnp-5809	55	25	.	.	PUNCT
fnp-5809	56	1	2	2	X
fnp-5809	56	2	.	.	X
fnp-5809	56	3	gap43	gap43	NOUN
fnp-5809	56	4	-	-	PUNCT
fnp-5809	56	5	dependent	dependent	ADJ
fnp-5809	56	6	transfer	transfer	NOUN
fnp-5809	56	7	of	of	ADP
fnp-5809	56	8	mitochondria	mitochondria	NOUN
fnp-5809	56	9	from	from	ADP
fnp-5809	56	10	astrocytes	astrocyte	NOUN
fnp-5809	56	11	to	to	ADP
fnp-5809	56	12	glioma	glioma	NOUN
fnp-5809	56	13	cells	cell	NOUN
fnp-5809	56	14	increases	increase	VERB
fnp-5809	56	15	cellular	cellular	ADJ
fnp-5809	56	16	proliferation	proliferation	NOUN
fnp-5809	56	17	and	and	CCONJ
fnp-5809	56	18	self	self	NOUN
fnp-5809	56	19	-	-	PUNCT
fnp-5809	56	20	renewal	renewal	NOUN
fnp-5809	56	21	[	[	X
fnp-5809	56	22	watson	watson	PROPN
fnp-5809	56	23	et	et	PROPN
fnp-5809	56	24	al	al	PROPN
fnp-5809	56	25	.	.	PROPN
fnp-5809	56	26	,	,	PUNCT
fnp-5809	56	27	2023	2023	NUM
fnp-5809	56	28	]	]	PUNCT
fnp-5809	56	29	.	.	PUNCT
fnp-5809	57	1	it	it	PRON
fnp-5809	57	2	has	have	AUX
fnp-5809	57	3	previously	previously	ADV
fnp-5809	57	4	been	be	AUX
fnp-5809	57	5	shown	show	VERB
fnp-5809	57	6	that	that	SCONJ
fnp-5809	57	7	brain	brain	NOUN
fnp-5809	57	8	cells	cell	NOUN
fnp-5809	57	9	interact	interact	VERB
fnp-5809	57	10	via	via	ADP
fnp-5809	57	11	tunneling	tunneling	NOUN
fnp-5809	57	12	nanotubes	nanotube	NOUN
fnp-5809	57	13	(	(	PUNCT
fnp-5809	57	14	tnt	tnt	NOUN
fnp-5809	57	15	)	)	PUNCT
fnp-5809	57	16	,	,	PUNCT
fnp-5809	57	17	in	in	ADP
fnp-5809	57	18	neoplastic	neoplastic	ADJ
fnp-5809	57	19	conditions	condition	NOUN
fnp-5809	57	20	also	also	ADV
fnp-5809	57	21	known	know	VERB
fnp-5809	57	22	as	as	ADP
fnp-5809	57	23	tumor	tumor	NOUN
fnp-5809	57	24	microtubules	microtubule	NOUN
fnp-5809	57	25	(	(	PUNCT
fnp-5809	57	26	mts	mts	NOUN
fnp-5809	57	27	)	)	PUNCT
fnp-5809	57	28	,	,	PUNCT
fnp-5809	57	29	by	by	ADP
fnp-5809	57	30	which	which	PRON
fnp-5809	57	31	larger	large	ADJ
fnp-5809	57	32	cellular	cellular	ADJ
fnp-5809	57	33	organelles	organelle	NOUN
fnp-5809	57	34	such	such	ADJ
fnp-5809	57	35	as	as	ADP
fnp-5809	57	36	mitochondria	mitochondria	NOUN
fnp-5809	57	37	can	can	AUX
fnp-5809	57	38	be	be	AUX
fnp-5809	57	39	transferred	transfer	VERB
fnp-5809	57	40	.	.	PUNCT
fnp-5809	58	1	in	in	ADP
fnp-5809	58	2	particular	particular	ADJ
fnp-5809	58	3	,	,	PUNCT
fnp-5809	58	4	glioblastoma	glioblastoma	NOUN
fnp-5809	58	5	cell	cell	NOUN
fnp-5809	58	6	-	-	PUNCT
fnp-5809	58	7	derived	derive	VERB
fnp-5809	58	8	mitochondria	mitochondria	NOUN
fnp-5809	58	9	can	can	AUX
fnp-5809	58	10	be	be	AUX
fnp-5809	58	11	shuttled	shuttle	VERB
fnp-5809	58	12	into	into	ADP
fnp-5809	58	13	non	non	ADJ
fnp-5809	58	14	-	-	ADJ
fnp-5809	58	15	neoplastic	neoplastic	ADJ
fnp-5809	58	16	astrocytes	astrocyte	NOUN
fnp-5809	58	17	that	that	PRON
fnp-5809	58	18	subsequently	subsequently	ADV
fnp-5809	58	19	adapted	adapt	VERB
fnp-5809	58	20	to	to	ADP
fnp-5809	58	21	tumor	tumor	NOUN
fnp-5809	58	22	-	-	PUNCT
fnp-5809	58	23	like	like	ADJ
fnp-5809	58	24	metabolism	metabolism	NOUN
fnp-5809	58	25	and	and	CCONJ
fnp-5809	58	26	hypoxia	hypoxia	NOUN
fnp-5809	58	27	conditions	condition	NOUN
fnp-5809	58	28	[	[	X
fnp-5809	58	29	valdebenito	valdebenito	ADJ
fnp-5809	58	30	et	et	PROPN
fnp-5809	58	31	al	al	PROPN
fnp-5809	58	32	.	.	PROPN
fnp-5809	58	33	,	,	PUNCT
fnp-5809	58	34	2021	2021	NUM
fnp-5809	58	35	]	]	PUNCT
fnp-5809	58	36	.	.	PUNCT
fnp-5809	59	1	the	the	DET
fnp-5809	59	2	study	study	NOUN
fnp-5809	59	3	of	of	ADP
fnp-5809	59	4	watson	watson	PROPN
fnp-5809	59	5	et	et	PROPN
fnp-5809	59	6	al	al	PROPN
fnp-5809	59	7	.	.	PROPN
fnp-5809	59	8	analyzed	analyze	VERB
fnp-5809	59	9	the	the	DET
fnp-5809	59	10	reverse	reverse	NOUN
fnp-5809	59	11	,	,	PUNCT
fnp-5809	59	12	namely	namely	ADV
fnp-5809	59	13	how	how	SCONJ
fnp-5809	59	14	mitochondria	mitochondria	NOUN
fnp-5809	59	15	are	be	AUX
fnp-5809	59	16	transported	transport	VERB
fnp-5809	59	17	from	from	ADP
fnp-5809	59	18	residual	residual	ADJ
fnp-5809	59	19	non	non	ADJ
fnp-5809	59	20	-	-	ADJ
fnp-5809	59	21	neoplastic	neoplastic	ADJ
fnp-5809	59	22	astrocytes	astrocyte	NOUN
fnp-5809	59	23	to	to	ADP
fnp-5809	59	24	glioma	glioma	NOUN
fnp-5809	59	25	cells	cell	NOUN
fnp-5809	59	26	and	and	CCONJ
fnp-5809	59	27	how	how	SCONJ
fnp-5809	59	28	this	this	DET
fnp-5809	59	29	impacted	impact	VERB
fnp-5809	59	30	glioma	glioma	NOUN
fnp-5809	59	31	cell	cell	NOUN
fnp-5809	59	32	function	function	NOUN
fnp-5809	59	33	[	[	X
fnp-5809	59	34	watson	watson	PROPN
fnp-5809	59	35	et	et	PROPN
fnp-5809	59	36	al	al	PROPN
fnp-5809	59	37	.	.	PROPN
fnp-5809	59	38	,	,	PUNCT
fnp-5809	59	39	2023	2023	NUM
fnp-5809	59	40	]	]	PUNCT
fnp-5809	59	41	.	.	PUNCT
fnp-5809	60	1	to	to	PART
fnp-5809	60	2	elucidate	elucidate	VERB
fnp-5809	60	3	this	this	DET
fnp-5809	60	4	question	question	NOUN
fnp-5809	60	5	,	,	PUNCT
fnp-5809	60	6	the	the	DET
fnp-5809	60	7	authors	author	NOUN
fnp-5809	60	8	used	use	VERB
fnp-5809	60	9	different	different	ADJ
fnp-5809	60	10	mouse	mouse	NOUN
fnp-5809	60	11	and	and	CCONJ
fnp-5809	60	12	rat	rat	NOUN
fnp-5809	60	13	glioma	glioma	NOUN
fnp-5809	60	14	models	model	NOUN
fnp-5809	60	15	with	with	ADP
fnp-5809	60	16	mitochondria	mitochondria	NOUN
fnp-5809	60	17	and	and	CCONJ
fnp-5809	60	18	glioma	glioma	NOUN
fnp-5809	60	19	cells	cell	NOUN
fnp-5809	60	20	fluorescing	fluoresce	VERB
fnp-5809	60	21	in	in	ADP
fnp-5809	60	22	different	different	ADJ
fnp-5809	60	23	colors	color	NOUN
fnp-5809	60	24	.	.	PUNCT
fnp-5809	61	1	by	by	ADP
fnp-5809	61	2	doing	do	VERB
fnp-5809	61	3	so	so	ADV
fnp-5809	61	4	,	,	PUNCT
fnp-5809	61	5	they	they	PRON
fnp-5809	61	6	could	could	AUX
fnp-5809	61	7	demonstrate	demonstrate	VERB
fnp-5809	61	8	that	that	SCONJ
fnp-5809	61	9	between	between	ADP
fnp-5809	61	10	15	15	NUM
fnp-5809	61	11	to	to	PART
fnp-5809	61	12	60	60	NUM
fnp-5809	61	13	 	 	SPACE
fnp-5809	61	14	%	%	NOUN
fnp-5809	61	15	of	of	ADP
fnp-5809	61	16	glioma	glioma	NOUN
fnp-5809	61	17	cells	cell	NOUN
fnp-5809	61	18	incorporated	incorporate	VERB
fnp-5809	61	19	mitochondria	mitochondria	NOUN
fnp-5809	61	20	of	of	ADP
fnp-5809	61	21	non	non	ADJ
fnp-5809	61	22	-	-	ADJ
fnp-5809	61	23	neoplastic	neoplastic	ADJ
fnp-5809	61	24	astrocytic	astrocytic	ADJ
fnp-5809	61	25	,	,	PUNCT
fnp-5809	61	26	and	and	CCONJ
fnp-5809	61	27	to	to	ADP
fnp-5809	61	28	a	a	DET
fnp-5809	61	29	lesser	less	ADJ
fnp-5809	61	30	extent	extent	NOUN
fnp-5809	61	31	also	also	ADV
fnp-5809	61	32	microglial	microglial	ADJ
fnp-5809	61	33	origin	origin	NOUN
fnp-5809	61	34	.	.	PUNCT
fnp-5809	62	1	it	it	PRON
fnp-5809	62	2	could	could	AUX
fnp-5809	62	3	further	far	ADV
fnp-5809	62	4	be	be	AUX
fnp-5809	62	5	shown	show	VERB
fnp-5809	62	6	that	that	SCONJ
fnp-5809	62	7	physical	physical	ADJ
fnp-5809	62	8	contact	contact	NOUN
fnp-5809	62	9	between	between	ADP
fnp-5809	62	10	non	non	ADJ
fnp-5809	62	11	-	-	ADJ
fnp-5809	62	12	neoplastic	neoplastic	ADJ
fnp-5809	62	13	astrocytes	astrocyte	NOUN
fnp-5809	62	14	and	and	CCONJ
fnp-5809	62	15	glioma	glioma	NOUN
fnp-5809	62	16	cells	cell	NOUN
fnp-5809	62	17	is	be	AUX
fnp-5809	62	18	necessary	necessary	ADJ
fnp-5809	62	19	for	for	ADP
fnp-5809	62	20	mitochondrial	mitochondrial	ADJ
fnp-5809	62	21	transfer	transfer	NOUN
fnp-5809	62	22	.	.	PUNCT
fnp-5809	63	1	inhibition	inhibition	NOUN
fnp-5809	63	2	of	of	ADP
fnp-5809	63	3	actin	actin	NOUN
fnp-5809	63	4	polymerization	polymerization	NOUN
fnp-5809	63	5	by	by	ADP
fnp-5809	63	6	cytochalasin	cytochalasin	PROPN
fnp-5809	63	7	b	b	PROPN
fnp-5809	63	8	reduced	reduce	VERB
fnp-5809	63	9	the	the	DET
fnp-5809	63	10	mitochondrial	mitochondrial	ADJ
fnp-5809	63	11	transfer	transfer	NOUN
fnp-5809	63	12	rate	rate	NOUN
fnp-5809	63	13	,	,	PUNCT
fnp-5809	63	14	indicating	indicate	VERB
fnp-5809	63	15	an	an	DET
fnp-5809	63	16	important	important	ADJ
fnp-5809	63	17	role	role	NOUN
fnp-5809	63	18	of	of	ADP
fnp-5809	63	19	actin	actin	NOUN
fnp-5809	63	20	cytoskeleton	cytoskeleton	PROPN
fnp-5809	63	21	remodeling	remodeling	NOUN
fnp-5809	63	22	as	as	ADP
fnp-5809	63	23	an	an	DET
fnp-5809	63	24	underlying	underlying	ADJ
fnp-5809	63	25	mechanism	mechanism	NOUN
fnp-5809	63	26	.	.	PUNCT
fnp-5809	64	1	hypothesizing	hypothesize	VERB
fnp-5809	64	2	that	that	SCONJ
fnp-5809	64	3	the	the	DET
fnp-5809	64	4	actin	actin	NOUN
fnp-5809	64	5	-	-	PUNCT
fnp-5809	64	6	associated	associate	VERB
fnp-5809	64	7	protein	protein	NOUN
fnp-5809	64	8	gap43	gap43	NOUN
fnp-5809	64	9	that	that	PRON
fnp-5809	64	10	is	be	AUX
fnp-5809	64	11	involved	involve	VERB
fnp-5809	64	12	in	in	ADP
fnp-5809	64	13	neurite	neurite	ADJ
fnp-5809	64	14	outgrowth	outgrowth	NOUN
fnp-5809	64	15	could	could	AUX
fnp-5809	64	16	be	be	AUX
fnp-5809	64	17	implicated	implicate	VERB
fnp-5809	64	18	in	in	ADP
fnp-5809	64	19	this	this	DET
fnp-5809	64	20	mechanism	mechanism	NOUN
fnp-5809	64	21	,	,	PUNCT
fnp-5809	64	22	the	the	DET
fnp-5809	64	23	authors	author	NOUN
fnp-5809	64	24	knocked	knock	VERB
fnp-5809	64	25	down	down	ADP
fnp-5809	64	26	gap43	gap43	NOUN
fnp-5809	64	27	and	and	CCONJ
fnp-5809	64	28	observed	observe	VERB
fnp-5809	64	29	significantly	significantly	ADV
fnp-5809	64	30	reduced	reduce	VERB
fnp-5809	64	31	mitochondrial	mitochondrial	ADJ
fnp-5809	64	32	transfer	transfer	NOUN
fnp-5809	64	33	.	.	PUNCT
fnp-5809	65	1	importantly	importantly	ADV
fnp-5809	65	2	,	,	PUNCT
fnp-5809	65	3	rna	rna	NOUN
fnp-5809	65	4	sequencing	sequencing	NOUN
fnp-5809	65	5	showed	show	VERB
fnp-5809	65	6	an	an	DET
fnp-5809	65	7	increase	increase	NOUN
fnp-5809	65	8	of	of	ADP
fnp-5809	65	9	gene	gene	NOUN
fnp-5809	65	10	activity	activity	NOUN
fnp-5809	65	11	related	relate	VERB
fnp-5809	65	12	to	to	PART
fnp-5809	65	13	electron	electron	NOUN
fnp-5809	65	14	transport	transport	NOUN
fnp-5809	65	15	and	and	CCONJ
fnp-5809	65	16	mitochondrial	mitochondrial	ADJ
fnp-5809	65	17	organization	organization	NOUN
fnp-5809	65	18	therefore	therefore	ADV
fnp-5809	65	19	suggesting	suggest	VERB
fnp-5809	65	20	a	a	DET
fnp-5809	65	21	functional	functional	ADJ
fnp-5809	65	22	implication	implication	NOUN
fnp-5809	65	23	of	of	ADP
fnp-5809	65	24	mitochondrial	mitochondrial	ADJ
fnp-5809	65	25	transfer	transfer	NOUN
fnp-5809	65	26	.	.	PUNCT
fnp-5809	66	1	this	this	PRON
fnp-5809	66	2	was	be	AUX
fnp-5809	66	3	corroborated	corroborate	VERB
fnp-5809	66	4	by	by	ADP
fnp-5809	66	5	metabolic	metabolic	NOUN
fnp-5809	66	6	analyses	analysis	NOUN
fnp-5809	66	7	showing	show	VERB
fnp-5809	66	8	a	a	DET
fnp-5809	66	9	higher	high	ADJ
fnp-5809	66	10	basal	basal	NOUN
fnp-5809	66	11	and	and	CCONJ
fnp-5809	66	12	maximal	maximal	ADJ
fnp-5809	66	13	respiration	respiration	NOUN
fnp-5809	66	14	rate	rate	NOUN
fnp-5809	66	15	in	in	ADP
fnp-5809	66	16	glioma	glioma	NOUN
fnp-5809	66	17	cells	cell	NOUN
fnp-5809	66	18	having	having	AUX
fnp-5809	66	19	incorporated	incorporate	VERB
fnp-5809	66	20	a	a	DET
fnp-5809	66	21	higher	high	ADJ
fnp-5809	66	22	number	number	NOUN
fnp-5809	66	23	of	of	ADP
fnp-5809	66	24	astrocyte	astrocyte	NOUN
fnp-5809	66	25	-	-	PUNCT
fnp-5809	66	26	derived	derive	VERB
fnp-5809	66	27	mitochondria	mitochondria	NOUN
fnp-5809	66	28	.	.	PUNCT
fnp-5809	67	1	this	this	DET
fnp-5809	67	2	glioma	glioma	NOUN
fnp-5809	67	3	fraction	fraction	NOUN
fnp-5809	67	4	was	be	AUX
fnp-5809	67	5	also	also	ADV
fnp-5809	67	6	more	more	ADV
fnp-5809	67	7	aerobic	aerobic	ADJ
fnp-5809	67	8	and	and	CCONJ
fnp-5809	67	9	energetic	energetic	ADJ
fnp-5809	67	10	as	as	SCONJ
fnp-5809	67	11	compared	compare	VERB
fnp-5809	67	12	to	to	ADP
fnp-5809	67	13	their	their	PRON
fnp-5809	67	14	counterpart	counterpart	NOUN
fnp-5809	67	15	with	with	ADP
fnp-5809	67	16	lower	low	ADJ
fnp-5809	67	17	mitochondria	mitochondria	NOUN
fnp-5809	67	18	incorporation	incorporation	NOUN
fnp-5809	67	19	rate	rate	NOUN
fnp-5809	67	20	.	.	PUNCT
fnp-5809	68	1	in	in	ADP
fnp-5809	68	2	addition	addition	NOUN
fnp-5809	68	3	,	,	PUNCT
fnp-5809	68	4	amino	amino	NOUN
fnp-5809	68	5	acid	acid	NOUN
fnp-5809	68	6	and	and	CCONJ
fnp-5809	68	7	nucleotide	nucleotide	ADJ
fnp-5809	68	8	metabolism	metabolism	NOUN
fnp-5809	68	9	were	be	AUX
fnp-5809	68	10	significantly	significantly	ADV
fnp-5809	68	11	altered	alter	VERB
fnp-5809	68	12	in	in	ADP
fnp-5809	68	13	glioma	glioma	NOUN
fnp-5809	68	14	cells	cell	NOUN
fnp-5809	68	15	with	with	ADP
fnp-5809	68	16	a	a	DET
fnp-5809	68	17	higher	high	ADJ
fnp-5809	68	18	transfer	transfer	NOUN
fnp-5809	68	19	rate	rate	NOUN
fnp-5809	68	20	of	of	ADP
fnp-5809	68	21	mitochondria	mitochondria	PROPN
fnp-5809	68	22	indicating	indicate	VERB
fnp-5809	68	23	a	a	DET
fnp-5809	68	24	metabolic	metabolic	NOUN
fnp-5809	68	25	reprogramming	reprogramming	NOUN
fnp-5809	68	26	that	that	PRON
fnp-5809	68	27	might	might	AUX
fnp-5809	68	28	be	be	AUX
fnp-5809	68	29	important	important	ADJ
fnp-5809	68	30	for	for	ADP
fnp-5809	68	31	pro	pro	ADJ
fnp-5809	68	32	-	-	ADJ
fnp-5809	68	33	proliferative	proliferative	ADJ
fnp-5809	68	34	,	,	PUNCT
fnp-5809	68	35	antioxidative	antioxidative	ADJ
fnp-5809	68	36	and	and	CCONJ
fnp-5809	68	37	various	various	ADJ
fnp-5809	68	38	cell	cell	NOUN
fnp-5809	68	39	signaling	signal	VERB
fnp-5809	68	40	processes	process	NOUN
fnp-5809	68	41	.	.	PUNCT
fnp-5809	69	1	the	the	DET
fnp-5809	69	2	first	first	ADJ
fnp-5809	69	3	evidence	evidence	NOUN
fnp-5809	69	4	that	that	SCONJ
fnp-5809	69	5	this	this	DET
fnp-5809	69	6	mechanism	mechanism	NOUN
fnp-5809	69	7	might	might	AUX
fnp-5809	69	8	play	play	VERB
fnp-5809	69	9	an	an	DET
fnp-5809	69	10	important	important	ADJ
fnp-5809	69	11	clinical	clinical	ADJ
fnp-5809	69	12	role	role	NOUN
fnp-5809	69	13	in	in	ADP
fnp-5809	69	14	neurooncology	neurooncology	NOUN
fnp-5809	69	15	was	be	AUX
fnp-5809	69	16	observed	observe	VERB
fnp-5809	69	17	in	in	ADP
fnp-5809	69	18	a	a	DET
fnp-5809	69	19	mouse	mouse	NOUN
fnp-5809	69	20	glioma	glioma	NOUN
fnp-5809	69	21	model	model	NOUN
fnp-5809	69	22	in	in	ADP
fnp-5809	69	23	which	which	DET
fnp-5809	69	24	animals	animal	NOUN
fnp-5809	69	25	with	with	ADP
fnp-5809	69	26	glioma	glioma	NOUN
fnp-5809	69	27	cells	cell	NOUN
fnp-5809	69	28	that	that	PRON
fnp-5809	69	29	incorporated	incorporate	VERB
fnp-5809	69	30	astrocyte	astrocyte	NOUN
fnp-5809	69	31	-	-	PUNCT
fnp-5809	69	32	derived	derive	VERB
fnp-5809	69	33	mitochondria	mitochondria	NOUN
fnp-5809	69	34	showed	show	VERB
fnp-5809	69	35	significantly	significantly	ADV
fnp-5809	69	36	shorter	short	ADJ
fnp-5809	69	37	survival	survival	NOUN
fnp-5809	69	38	rates	rate	NOUN
fnp-5809	69	39	as	as	ADP
fnp-5809	69	40	compared	compare	VERB
fnp-5809	69	41	to	to	ADP
fnp-5809	69	42	glioma	glioma	NOUN
fnp-5809	69	43	cells	cell	NOUN
fnp-5809	69	44	without	without	ADP
fnp-5809	69	45	mitochondria	mitochondria	NOUN
fnp-5809	69	46	transfer	transfer	NOUN
fnp-5809	69	47	(	(	PUNCT
fnp-5809	69	48	summary	summary	NOUN
fnp-5809	69	49	of	of	ADP
fnp-5809	69	50	the	the	DET
fnp-5809	69	51	proposed	propose	VERB
fnp-5809	69	52	mechanism	mechanism	NOUN
fnp-5809	69	53	in	in	ADP
fnp-5809	69	54	figure	figure	NOUN
fnp-5809	69	55	2	2	NUM
fnp-5809	69	56	)	)	PUNCT
fnp-5809	69	57	.	.	PUNCT
fnp-5809	70	1	figure	figure	VERB
fnp-5809	70	2	2	2	NUM
fnp-5809	70	3	:	:	PUNCT
fnp-5809	70	4	mitochondrial	mitochondrial	ADJ
fnp-5809	70	5	transfer	transfer	NOUN
fnp-5809	70	6	from	from	ADP
fnp-5809	70	7	residual	residual	ADJ
fnp-5809	70	8	non	non	ADJ
fnp-5809	70	9	-	-	ADJ
fnp-5809	70	10	neoplastic	neoplastic	ADJ
fnp-5809	70	11	astrocytes	astrocyte	NOUN
fnp-5809	70	12	to	to	ADP
fnp-5809	70	13	glioma	glioma	NOUN
fnp-5809	70	14	cells	cell	NOUN
fnp-5809	70	15	thereby	thereby	ADV
fnp-5809	70	16	conferring	confer	VERB
fnp-5809	70	17	respiratory	respiratory	ADJ
fnp-5809	70	18	and	and	CCONJ
fnp-5809	70	19	metabolic	metabolic	NOUN
fnp-5809	70	20	functions	function	NOUN
fnp-5809	70	21	linked	link	VERB
fnp-5809	70	22	to	to	ADP
fnp-5809	70	23	glioma	glioma	NOUN
fnp-5809	70	24	cell	cell	NOUN
fnp-5809	70	25	proliferation	proliferation	NOUN
fnp-5809	70	26	and	and	CCONJ
fnp-5809	70	27	tumorigenicity	tumorigenicity	NOUN
fnp-5809	70	28	.	.	PUNCT
fnp-5809	71	1	3	3	X
fnp-5809	71	2	.	.	X
fnp-5809	71	3	brain	brain	NOUN
fnp-5809	71	4	endothelial	endothelial	ADJ
fnp-5809	71	5	cell	cell	NOUN
fnp-5809	71	6	remodeling	remodeling	NOUN
fnp-5809	71	7	by	by	ADP
fnp-5809	71	8	cns	cns	NOUN
fnp-5809	71	9	metastatic	metastatic	ADJ
fnp-5809	71	10	cell	cell	NOUN
fnp-5809	71	11	-	-	PUNCT
fnp-5809	71	12	derived	derive	VERB
fnp-5809	71	13	matrix	matrix	NOUN
fnp-5809	71	14	-	-	PUNCT
fnp-5809	71	15	metalloprotease	metalloprotease	NOUN
fnp-5809	71	16	9	9	NUM
fnp-5809	71	17	(	(	PUNCT
fnp-5809	71	18	mmp9	mmp9	PROPN
fnp-5809	71	19	)	)	PUNCT
fnp-5809	71	20	as	as	ADP
fnp-5809	71	21	a	a	DET
fnp-5809	71	22	mechanism	mechanism	NOUN
fnp-5809	71	23	for	for	ADP
fnp-5809	71	24	extravasation	extravasation	NOUN
fnp-5809	72	1	[	[	X
fnp-5809	72	2	karreman	karreman	NOUN
fnp-5809	72	3	et	et	PROPN
fnp-5809	72	4	al	al	PROPN
fnp-5809	72	5	.	.	PROPN
fnp-5809	72	6	,	,	PUNCT
fnp-5809	72	7	2023	2023	NUM
fnp-5809	72	8	]	]	PUNCT
fnp-5809	72	9	.	.	PUNCT
fnp-5809	73	1	brain	brain	NOUN
fnp-5809	73	2	metastases	metastasis	NOUN
fnp-5809	73	3	still	still	ADV
fnp-5809	73	4	constitute	constitute	VERB
fnp-5809	73	5	the	the	DET
fnp-5809	73	6	most	most	ADV
fnp-5809	73	7	frequent	frequent	ADJ
fnp-5809	73	8	malignant	malignant	ADJ
fnp-5809	73	9	cns	cns	NOUN
fnp-5809	73	10	tumors	tumor	NOUN
fnp-5809	73	11	,	,	PUNCT
fnp-5809	73	12	being	be	AUX
fnp-5809	73	13	much	much	ADV
fnp-5809	73	14	more	more	ADV
fnp-5809	73	15	frequent	frequent	ADJ
fnp-5809	73	16	than	than	ADP
fnp-5809	73	17	their	their	PRON
fnp-5809	73	18	primary	primary	ADJ
fnp-5809	73	19	cns	cns	NOUN
fnp-5809	73	20	tumor	tumor	NOUN
fnp-5809	73	21	counterparts	counterpart	NOUN
fnp-5809	73	22	.	.	PUNCT
fnp-5809	74	1	there	there	PRON
fnp-5809	74	2	is	be	VERB
fnp-5809	74	3	a	a	DET
fnp-5809	74	4	broad	broad	ADJ
fnp-5809	74	5	agreement	agreement	NOUN
fnp-5809	74	6	on	on	ADP
fnp-5809	74	7	the	the	DET
fnp-5809	74	8	key	key	ADJ
fnp-5809	74	9	steps	step	NOUN
fnp-5809	74	10	of	of	ADP
fnp-5809	74	11	cancer	cancer	NOUN
fnp-5809	74	12	cell	cell	NOUN
fnp-5809	74	13	extravasation	extravasation	NOUN
fnp-5809	74	14	from	from	ADP
fnp-5809	74	15	the	the	DET
fnp-5809	74	16	bloodstream	bloodstream	NOUN
fnp-5809	74	17	to	to	ADP
fnp-5809	74	18	the	the	DET
fnp-5809	74	19	cns	cns	NOUN
fnp-5809	74	20	similarly	similarly	ADV
fnp-5809	74	21	to	to	ADP
fnp-5809	74	22	leukocyte	leukocyte	NOUN
fnp-5809	74	23	extravasation	extravasation	NOUN
fnp-5809	74	24	including	include	VERB
fnp-5809	74	25	a	a	DET
fnp-5809	74	26	)	)	PUNCT
fnp-5809	74	27	rolling	rolling	ADJ
fnp-5809	74	28	/	/	SYM
fnp-5809	74	29	adhesion	adhesion	NOUN
fnp-5809	74	30	of	of	ADP
fnp-5809	74	31	cancer	cancer	NOUN
fnp-5809	74	32	cells	cell	NOUN
fnp-5809	74	33	to	to	PART
fnp-5809	74	34	brain	brain	NOUN
fnp-5809	74	35	endothelia	endothelia	PROPN
fnp-5809	74	36	,	,	PUNCT
fnp-5809	74	37	b	b	X
fnp-5809	74	38	)	)	PUNCT
fnp-5809	74	39	alteration	alteration	NOUN
fnp-5809	74	40	of	of	ADP
fnp-5809	74	41	the	the	DET
fnp-5809	74	42	blood	blood	NOUN
fnp-5809	74	43	-	-	PUNCT
fnp-5809	74	44	brain	brain	NOUN
fnp-5809	74	45	barrier	barrier	NOUN
fnp-5809	74	46	(	(	PUNCT
fnp-5809	74	47	bbb	bbb	NOUN
fnp-5809	74	48	)	)	PUNCT
fnp-5809	74	49	permeability	permeability	NOUN
fnp-5809	74	50	and	and	CCONJ
fnp-5809	74	51	c	c	NOUN
fnp-5809	74	52	)	)	PUNCT
fnp-5809	74	53	trans	trans	ADJ
fnp-5809	74	54	-	-	ADJ
fnp-5809	74	55	endothelial	endothelial	ADJ
fnp-5809	74	56	migration	migration	NOUN
fnp-5809	74	57	,	,	PUNCT
fnp-5809	74	58	however	however	ADV
fnp-5809	74	59	,	,	PUNCT
fnp-5809	74	60	the	the	DET
fnp-5809	74	61	exact	exact	ADJ
fnp-5809	74	62	underlying	underlying	ADJ
fnp-5809	74	63	mechanisms	mechanism	NOUN
fnp-5809	74	64	are	be	AUX
fnp-5809	74	65	still	still	ADV
fnp-5809	74	66	not	not	PART
fnp-5809	74	67	fully	fully	ADV
fnp-5809	74	68	understood	understand	VERB
fnp-5809	74	69	[	[	X
fnp-5809	74	70	alsabbagh	alsabbagh	X
fnp-5809	74	71	et	et	PROPN
fnp-5809	74	72	al	al	PROPN
fnp-5809	74	73	.	.	PROPN
fnp-5809	74	74	,	,	PUNCT
fnp-5809	74	75	2023	2023	NUM
fnp-5809	74	76	]	]	PUNCT
fnp-5809	74	77	.	.	PUNCT
fnp-5809	75	1	previous	previous	ADJ
fnp-5809	75	2	observations	observation	NOUN
fnp-5809	75	3	,	,	PUNCT
fnp-5809	75	4	that	that	PRON
fnp-5809	75	5	primary	primary	ADJ
fnp-5809	75	6	cancer	cancer	NOUN
fnp-5809	75	7	cells	cell	NOUN
fnp-5809	75	8	are	be	AUX
fnp-5809	75	9	able	able	ADJ
fnp-5809	75	10	to	to	PART
fnp-5809	75	11	considerably	considerably	ADV
fnp-5809	75	12	change	change	VERB
fnp-5809	75	13	the	the	DET
fnp-5809	75	14	structure	structure	NOUN
fnp-5809	75	15	of	of	ADP
fnp-5809	75	16	brain	brain	NOUN
fnp-5809	75	17	vessels	vessel	NOUN
fnp-5809	76	1	[	[	X
fnp-5809	76	2	haskó	haskó	NOUN
fnp-5809	76	3	et	et	VERB
fnp-5809	76	4	al	al	PROPN
fnp-5809	76	5	.	.	PROPN
fnp-5809	76	6	,	,	PUNCT
fnp-5809	76	7	2019	2019	NUM
fnp-5809	76	8	]	]	PUNCT
fnp-5809	76	9	,	,	PUNCT
fnp-5809	76	10	prompted	prompt	VERB
fnp-5809	76	11	the	the	DET
fnp-5809	76	12	authors	author	NOUN
fnp-5809	76	13	to	to	ADP
fnp-5809	76	14	decipher	decipher	PROPN
fnp-5809	76	15	more	more	ADV
fnp-5809	76	16	precisely	precisely	ADV
fnp-5809	76	17	the	the	DET
fnp-5809	76	18	potential	potential	ADJ
fnp-5809	76	19	underlying	underlying	ADJ
fnp-5809	76	20	mechanism	mechanism	NOUN
fnp-5809	76	21	.	.	PUNCT
fnp-5809	77	1	by	by	ADP
fnp-5809	77	2	combining	combine	VERB
fnp-5809	77	3	fluorescent	fluorescent	NOUN
fnp-5809	77	4	and	and	CCONJ
fnp-5809	77	5	electron	electron	NOUN
fnp-5809	77	6	microscopy	microscopy	NOUN
fnp-5809	77	7	on	on	ADP
fnp-5809	77	8	murine	murine	ADJ
fnp-5809	77	9	brain	brain	NOUN
fnp-5809	77	10	metastasis	metastasis	NOUN
fnp-5809	77	11	models	model	NOUN
fnp-5809	77	12	,	,	PUNCT
fnp-5809	77	13	the	the	DET
fnp-5809	77	14	authors	author	NOUN
fnp-5809	77	15	were	be	AUX
fnp-5809	77	16	able	able	ADJ
fnp-5809	77	17	to	to	PART
fnp-5809	77	18	trace	trace	VERB
fnp-5809	77	19	the	the	DET
fnp-5809	77	20	moment	moment	NOUN
fnp-5809	77	21	of	of	ADP
fnp-5809	77	22	interaction	interaction	NOUN
fnp-5809	77	23	between	between	ADP
fnp-5809	77	24	cancer	cancer	NOUN
fnp-5809	77	25	and	and	CCONJ
fnp-5809	77	26	endothelial	endothelial	NOUN
fnp-5809	77	27	cells	cell	NOUN
fnp-5809	77	28	and	and	CCONJ
fnp-5809	77	29	study	study	VERB
fnp-5809	77	30	those	those	DET
fnp-5809	77	31	events	event	NOUN
fnp-5809	77	32	at	at	ADP
fnp-5809	77	33	high	high	ADJ
fnp-5809	77	34	resolution	resolution	NOUN
fnp-5809	77	35	.	.	PUNCT
fnp-5809	78	1	the	the	DET
fnp-5809	78	2	observed	observe	VERB
fnp-5809	78	3	vascular	vascular	ADJ
fnp-5809	78	4	arrest	arrest	NOUN
fnp-5809	78	5	of	of	ADP
fnp-5809	78	6	cancer	cancer	NOUN
fnp-5809	78	7	cells	cell	NOUN
fnp-5809	78	8	was	be	AUX
fnp-5809	78	9	mainly	mainly	ADV
fnp-5809	78	10	seen	see	VERB
fnp-5809	78	11	at	at	ADP
fnp-5809	78	12	vessel	vessel	ADJ
fnp-5809	78	13	branch	branch	NOUN
fnp-5809	78	14	points	point	NOUN
fnp-5809	78	15	where	where	SCONJ
fnp-5809	78	16	cancer	cancer	NOUN
fnp-5809	78	17	cells	cell	NOUN
fnp-5809	78	18	acquired	acquire	VERB
fnp-5809	78	19	an	an	DET
fnp-5809	78	20	elongated	elongate	VERB
fnp-5809	78	21	shape	shape	NOUN
fnp-5809	78	22	and	and	CCONJ
fnp-5809	78	23	surrounding	surround	VERB
fnp-5809	78	24	vessels	vessel	NOUN
fnp-5809	78	25	a	a	DET
fnp-5809	78	26	significantly	significantly	ADV
fnp-5809	78	27	dilated	dilate	VERB
fnp-5809	78	28	state	state	NOUN
fnp-5809	78	29	with	with	ADP
fnp-5809	78	30	disorganized	disorganized	ADJ
fnp-5809	78	31	basement	basement	NOUN
fnp-5809	78	32	membranes	membrane	NOUN
fnp-5809	78	33	.	.	PUNCT
fnp-5809	79	1	furthermore	furthermore	ADV
fnp-5809	79	2	,	,	PUNCT
fnp-5809	79	3	the	the	DET
fnp-5809	79	4	moment	moment	NOUN
fnp-5809	79	5	of	of	ADP
fnp-5809	79	6	extravasation	extravasation	NOUN
fnp-5809	79	7	could	could	AUX
fnp-5809	79	8	also	also	ADV
fnp-5809	79	9	be	be	AUX
fnp-5809	79	10	captured	capture	VERB
fnp-5809	79	11	by	by	ADP
fnp-5809	79	12	showing	show	VERB
fnp-5809	79	13	tumor	tumor	NOUN
fnp-5809	79	14	cell	cell	NOUN
fnp-5809	79	15	nuclei	nucleus	NOUN
fnp-5809	79	16	both	both	CCONJ
fnp-5809	79	17	partly	partly	ADV
fnp-5809	79	18	inside	inside	ADP
fnp-5809	79	19	and	and	CCONJ
fnp-5809	79	20	outside	outside	ADV
fnp-5809	79	21	of	of	ADP
fnp-5809	79	22	brain	brain	NOUN
fnp-5809	79	23	capillaries	capillary	NOUN
fnp-5809	79	24	with	with	ADP
fnp-5809	79	25	a	a	DET
fnp-5809	79	26	nuclear	nuclear	ADJ
fnp-5809	79	27	diameter	diameter	NOUN
fnp-5809	79	28	of	of	ADP
fnp-5809	79	29	less	less	ADJ
fnp-5809	79	30	than	than	ADP
fnp-5809	79	31	1	1	NUM
fnp-5809	79	32	µm	µm	NOUN
fnp-5809	79	33	.	.	PUNCT
fnp-5809	80	1	the	the	DET
fnp-5809	80	2	most	most	ADV
fnp-5809	80	3	prominent	prominent	ADJ
fnp-5809	80	4	disruption	disruption	NOUN
fnp-5809	80	5	of	of	ADP
fnp-5809	80	6	the	the	DET
fnp-5809	80	7	basement	basement	NOUN
fnp-5809	80	8	membranes	membrane	NOUN
fnp-5809	80	9	was	be	AUX
fnp-5809	80	10	observed	observe	VERB
fnp-5809	80	11	during	during	ADP
fnp-5809	80	12	the	the	DET
fnp-5809	80	13	extravasation	extravasation	NOUN
fnp-5809	80	14	process	process	NOUN
fnp-5809	80	15	of	of	ADP
fnp-5809	80	16	cancer	cancer	NOUN
fnp-5809	80	17	cells	cell	NOUN
fnp-5809	80	18	,	,	PUNCT
fnp-5809	80	19	without	without	ADP
fnp-5809	80	20	surpassing	surpass	VERB
fnp-5809	80	21	the	the	DET
fnp-5809	80	22	astrocytic	astrocytic	ADJ
fnp-5809	80	23	or	or	CCONJ
fnp-5809	80	24	microglial	microglial	ADJ
fnp-5809	80	25	cell	cell	NOUN
fnp-5809	80	26	layers	layer	NOUN
fnp-5809	80	27	.	.	PUNCT
fnp-5809	81	1	brain	brain	NOUN
fnp-5809	81	2	capillaries	capillary	NOUN
fnp-5809	81	3	affected	affect	VERB
fnp-5809	81	4	by	by	ADP
fnp-5809	81	5	cancer	cancer	NOUN
fnp-5809	81	6	cell	cell	NOUN
fnp-5809	81	7	extravasation	extravasation	NOUN
fnp-5809	81	8	showed	show	VERB
fnp-5809	81	9	three	three	NUM
fnp-5809	81	10	major	major	ADJ
fnp-5809	81	11	,	,	PUNCT
fnp-5809	81	12	reproducible	reproducible	ADJ
fnp-5809	81	13	findings	finding	NOUN
fnp-5809	81	14	,	,	PUNCT
fnp-5809	81	15	namely	namely	ADV
fnp-5809	81	16	a	a	X
fnp-5809	81	17	)	)	PUNCT
fnp-5809	81	18	the	the	DET
fnp-5809	81	19	formation	formation	NOUN
fnp-5809	81	20	of	of	ADP
fnp-5809	81	21	neo	neo	PROPN
fnp-5809	81	22	-	-	PROPN
fnp-5809	81	23	lumina	lumina	NOUN
fnp-5809	81	24	parallel	parallel	NOUN
fnp-5809	81	25	to	to	ADP
fnp-5809	81	26	the	the	DET
fnp-5809	81	27	pre	pre	ADJ
fnp-5809	81	28	-	-	ADJ
fnp-5809	81	29	existing	existing	ADJ
fnp-5809	81	30	ones	one	NOUN
fnp-5809	81	31	,	,	PUNCT
fnp-5809	81	32	b	b	X
fnp-5809	81	33	)	)	PUNCT
fnp-5809	81	34	formation	formation	NOUN
fnp-5809	81	35	of	of	ADP
fnp-5809	81	36	endothelial	endothelial	ADJ
fnp-5809	81	37	cell	cell	NOUN
fnp-5809	81	38	projections	projection	NOUN
fnp-5809	81	39	and	and	CCONJ
fnp-5809	81	40	c	c	NOUN
fnp-5809	81	41	)	)	PUNCT
fnp-5809	81	42	obstruction	obstruction	NOUN
fnp-5809	81	43	of	of	ADP
fnp-5809	81	44	brain	brain	NOUN
fnp-5809	81	45	capillary	capillary	ADJ
fnp-5809	81	46	lumina	lumina	NOUN
fnp-5809	81	47	by	by	ADP
fnp-5809	81	48	swollen	swollen	ADJ
fnp-5809	81	49	endothelial	endothelial	ADJ
fnp-5809	81	50	cells	cell	NOUN
fnp-5809	81	51	(	(	PUNCT
fnp-5809	81	52	figure	figure	NOUN
fnp-5809	81	53	3	3	NUM
fnp-5809	81	54	)	)	PUNCT
fnp-5809	81	55	.	.	PUNCT
fnp-5809	82	1	of	of	ADP
fnp-5809	82	2	note	note	NOUN
fnp-5809	82	3	,	,	PUNCT
fnp-5809	82	4	those	those	DET
fnp-5809	82	5	changes	change	NOUN
fnp-5809	82	6	were	be	AUX
fnp-5809	82	7	reversible	reversible	ADJ
fnp-5809	82	8	within	within	ADP
fnp-5809	82	9	4	4	NUM
fnp-5809	82	10	days	day	NOUN
fnp-5809	82	11	if	if	SCONJ
fnp-5809	82	12	cancer	cancer	NOUN
fnp-5809	82	13	cells	cell	NOUN
fnp-5809	82	14	left	leave	VERB
fnp-5809	82	15	the	the	DET
fnp-5809	82	16	respective	respective	ADJ
fnp-5809	82	17	blood	blood	NOUN
fnp-5809	82	18	vessel	vessel	NOUN
fnp-5809	82	19	without	without	ADP
fnp-5809	82	20	performing	perform	VERB
fnp-5809	82	21	extravasation	extravasation	NOUN
fnp-5809	82	22	.	.	PUNCT
fnp-5809	83	1	furthermore	furthermore	ADV
fnp-5809	83	2	,	,	PUNCT
fnp-5809	83	3	the	the	DET
fnp-5809	83	4	faster	fast	ADJ
fnp-5809	83	5	cancer	cancer	NOUN
fnp-5809	83	6	cells	cell	NOUN
fnp-5809	83	7	were	be	AUX
fnp-5809	83	8	able	able	ADJ
fnp-5809	83	9	to	to	PART
fnp-5809	83	10	extravasate	extravasate	VERB
fnp-5809	83	11	,	,	PUNCT
fnp-5809	83	12	the	the	PRON
fnp-5809	83	13	more	more	ADV
fnp-5809	83	14	successful	successful	ADJ
fnp-5809	83	15	the	the	DET
fnp-5809	83	16	survival	survival	NOUN
fnp-5809	83	17	rate	rate	NOUN
fnp-5809	83	18	of	of	ADP
fnp-5809	83	19	those	those	DET
fnp-5809	83	20	cells	cell	NOUN
fnp-5809	83	21	was	be	AUX
fnp-5809	83	22	in	in	ADP
fnp-5809	83	23	the	the	DET
fnp-5809	83	24	perivascular	perivascular	ADJ
fnp-5809	83	25	niche	niche	NOUN
fnp-5809	83	26	.	.	PUNCT
fnp-5809	84	1	once	once	SCONJ
fnp-5809	84	2	cancer	cancer	NOUN
fnp-5809	84	3	cells	cell	NOUN
fnp-5809	84	4	successfully	successfully	ADV
fnp-5809	84	5	extravasated	extravasate	VERB
fnp-5809	84	6	and	and	CCONJ
fnp-5809	84	7	started	start	VERB
fnp-5809	84	8	perivascular	perivascular	ADJ
fnp-5809	84	9	metastatic	metastatic	ADJ
fnp-5809	84	10	growth	growth	NOUN
fnp-5809	84	11	,	,	PUNCT
fnp-5809	84	12	prominent	prominent	ADJ
fnp-5809	84	13	endothelial	endothelial	NOUN
fnp-5809	84	14	cell	cell	NOUN
fnp-5809	84	15	remodeling	remodeling	NOUN
fnp-5809	84	16	led	lead	VERB
fnp-5809	84	17	to	to	ADP
fnp-5809	84	18	the	the	DET
fnp-5809	84	19	formation	formation	NOUN
fnp-5809	84	20	of	of	ADP
fnp-5809	84	21	capillary	capillary	ADJ
fnp-5809	84	22	loops	loop	NOUN
fnp-5809	84	23	that	that	PRON
fnp-5809	84	24	followed	follow	VERB
fnp-5809	84	25	the	the	DET
fnp-5809	84	26	localization	localization	NOUN
fnp-5809	84	27	of	of	ADP
fnp-5809	84	28	tumor	tumor	NOUN
fnp-5809	84	29	cells	cell	NOUN
fnp-5809	84	30	.	.	PUNCT
fnp-5809	85	1	the	the	DET
fnp-5809	85	2	formation	formation	NOUN
fnp-5809	85	3	of	of	ADP
fnp-5809	85	4	capillary	capillary	ADJ
fnp-5809	85	5	loops	loop	NOUN
fnp-5809	85	6	was	be	AUX
fnp-5809	85	7	even	even	ADV
fnp-5809	85	8	a	a	DET
fnp-5809	85	9	prerequisite	prerequisite	NOUN
fnp-5809	85	10	for	for	ADP
fnp-5809	85	11	the	the	DET
fnp-5809	85	12	formation	formation	NOUN
fnp-5809	85	13	of	of	ADP
fnp-5809	85	14	macrometastases	macrometastase	NOUN
fnp-5809	85	15	.	.	PUNCT
fnp-5809	86	1	this	this	DET
fnp-5809	86	2	mechanism	mechanism	NOUN
fnp-5809	86	3	was	be	AUX
fnp-5809	86	4	mediated	mediate	VERB
fnp-5809	86	5	by	by	ADP
fnp-5809	86	6	cancer	cancer	NOUN
fnp-5809	86	7	cell	cell	NOUN
fnp-5809	86	8	derived	derive	VERB
fnp-5809	86	9	matrix	matrix	NOUN
fnp-5809	86	10	metalloprotease	metalloprotease	NOUN
fnp-5809	86	11	9	9	NUM
fnp-5809	86	12	(	(	PUNCT
fnp-5809	86	13	mmp9	mmp9	PROPN
fnp-5809	86	14	)	)	PUNCT
fnp-5809	86	15	.	.	PUNCT
fnp-5809	87	1	pharmacological	pharmacological	NOUN
fnp-5809	87	2	or	or	CCONJ
fnp-5809	87	3	genetic	genetic	ADJ
fnp-5809	87	4	inhibition	inhibition	NOUN
fnp-5809	87	5	of	of	ADP
fnp-5809	87	6	mmp9	mmp9	ADJ
fnp-5809	87	7	expression	expression	NOUN
fnp-5809	87	8	led	lead	VERB
fnp-5809	87	9	to	to	ADP
fnp-5809	87	10	significantly	significantly	ADV
fnp-5809	87	11	reduced	reduce	VERB
fnp-5809	87	12	endothelial	endothelial	ADJ
fnp-5809	87	13	cell	cell	NOUN
fnp-5809	87	14	remodeling	remodeling	NOUN
fnp-5809	87	15	,	,	PUNCT
fnp-5809	87	16	extravasation	extravasation	NOUN
fnp-5809	87	17	of	of	ADP
fnp-5809	87	18	cancer	cancer	NOUN
fnp-5809	87	19	cells	cell	NOUN
fnp-5809	87	20	,	,	PUNCT
fnp-5809	87	21	and	and	CCONJ
fnp-5809	87	22	the	the	DET
fnp-5809	87	23	formation	formation	NOUN
fnp-5809	87	24	of	of	ADP
fnp-5809	87	25	metastases	metastasis	NOUN
fnp-5809	87	26	.	.	PUNCT
fnp-5809	88	1	these	these	DET
fnp-5809	88	2	findings	finding	NOUN
fnp-5809	88	3	contribute	contribute	VERB
fnp-5809	88	4	to	to	ADP
fnp-5809	88	5	a	a	DET
fnp-5809	88	6	better	well	ADJ
fnp-5809	88	7	understanding	understanding	NOUN
fnp-5809	88	8	of	of	ADP
fnp-5809	88	9	brain	brain	NOUN
fnp-5809	88	10	metastasis	metastasis	NOUN
fnp-5809	88	11	formation	formation	NOUN
fnp-5809	88	12	and	and	CCONJ
fnp-5809	88	13	may	may	AUX
fnp-5809	88	14	pave	pave	VERB
fnp-5809	88	15	the	the	DET
fnp-5809	88	16	way	way	NOUN
fnp-5809	88	17	for	for	ADP
fnp-5809	88	18	new	new	ADJ
fnp-5809	88	19	prevention	prevention	NOUN
fnp-5809	88	20	or	or	CCONJ
fnp-5809	88	21	treatment	treatment	NOUN
fnp-5809	88	22	strategies	strategy	NOUN
fnp-5809	88	23	.	.	PUNCT
fnp-5809	89	1	figure	figure	VERB
fnp-5809	89	2	3	3	NUM
fnp-5809	89	3	:	:	PUNCT
fnp-5809	89	4	alteration	alteration	NOUN
fnp-5809	89	5	of	of	ADP
fnp-5809	89	6	brain	brain	NOUN
fnp-5809	89	7	endothelium	endothelium	NOUN
fnp-5809	89	8	upon	upon	SCONJ
fnp-5809	89	9	interaction	interaction	NOUN
fnp-5809	89	10	with	with	ADP
fnp-5809	89	11	mmp9	mmp9	NOUN
fnp-5809	89	12	producing	produce	VERB
fnp-5809	89	13	cancer	cancer	NOUN
fnp-5809	89	14	cells	cell	NOUN
fnp-5809	89	15	.	.	PUNCT
fnp-5809	90	1	4	4	X
fnp-5809	90	2	.	.	X
fnp-5809	90	3	microglia	microglia	ADJ
fnp-5809	90	4	suppress	suppress	ADJ
fnp-5809	90	5	breast	breast	NOUN
fnp-5809	90	6	cancer	cancer	NOUN
fnp-5809	90	7	brain	brain	NOUN
fnp-5809	90	8	metastasis	metastasis	NOUN
fnp-5809	90	9	formation	formation	NOUN
fnp-5809	91	1	[	[	X
fnp-5809	91	2	evans	evans	PROPN
fnp-5809	91	3	et	et	PROPN
fnp-5809	91	4	al	al	PROPN
fnp-5809	91	5	.	.	PROPN
fnp-5809	91	6	,	,	PUNCT
fnp-5809	91	7	2023	2023	NUM
fnp-5809	91	8	]	]	PUNCT
fnp-5809	91	9	.	.	PUNCT
fnp-5809	92	1	multiple	multiple	ADJ
fnp-5809	92	2	studies	study	NOUN
fnp-5809	92	3	have	have	AUX
fnp-5809	92	4	suggested	suggest	VERB
fnp-5809	92	5	a	a	DET
fnp-5809	92	6	detrimental	detrimental	ADJ
fnp-5809	92	7	role	role	NOUN
fnp-5809	92	8	of	of	ADP
fnp-5809	92	9	microglia	microglia	NOUN
fnp-5809	92	10	in	in	ADP
fnp-5809	92	11	the	the	DET
fnp-5809	92	12	development	development	NOUN
fnp-5809	92	13	and/or	and/or	CCONJ
fnp-5809	92	14	progression	progression	NOUN
fnp-5809	92	15	of	of	ADP
fnp-5809	92	16	brain	brain	NOUN
fnp-5809	92	17	metastases	metastasis	NOUN
fnp-5809	92	18	[	[	X
fnp-5809	92	19	izraely	izraely	ADV
fnp-5809	92	20	s	s	VERB
fnp-5809	92	21	et	et	NOUN
fnp-5809	92	22	al	al	PROPN
fnp-5809	92	23	.	.	PROPN
fnp-5809	92	24	,	,	PUNCT
fnp-5809	92	25	2023	2023	NUM
fnp-5809	92	26	;	;	PUNCT
fnp-5809	92	27	pukrop	pukrop	NOUN
fnp-5809	92	28	et	et	PROPN
fnp-5809	92	29	al	al	PROPN
fnp-5809	92	30	.	.	PROPN
fnp-5809	92	31	,	,	PUNCT
fnp-5809	92	32	2010	2010	NUM
fnp-5809	92	33	]	]	PUNCT
fnp-5809	92	34	.	.	PUNCT
fnp-5809	93	1	to	to	PART
fnp-5809	93	2	overcome	overcome	VERB
fnp-5809	93	3	the	the	DET
fnp-5809	93	4	issue	issue	NOUN
fnp-5809	93	5	of	of	ADP
fnp-5809	93	6	distinguishing	distinguish	VERB
fnp-5809	93	7	the	the	DET
fnp-5809	93	8	contribution	contribution	NOUN
fnp-5809	93	9	of	of	ADP
fnp-5809	93	10	primary	primary	ADJ
fnp-5809	93	11	cerebral	cerebral	ADJ
fnp-5809	93	12	microglia	microglia	NOUN
fnp-5809	93	13	from	from	ADP
fnp-5809	93	14	secondarily	secondarily	ADV
fnp-5809	93	15	invaded	invade	VERB
fnp-5809	93	16	cells	cell	NOUN
fnp-5809	93	17	of	of	ADP
fnp-5809	93	18	the	the	DET
fnp-5809	93	19	myeloid	myeloid	ADJ
fnp-5809	93	20	lineage	lineage	NOUN
fnp-5809	93	21	(	(	PUNCT
fnp-5809	93	22	most	most	ADV
fnp-5809	93	23	importantly	importantly	ADV
fnp-5809	93	24	macrophages	macrophage	NOUN
fnp-5809	93	25	)	)	PUNCT
fnp-5809	93	26	,	,	PUNCT
fnp-5809	93	27	the	the	DET
fnp-5809	93	28	authors	author	NOUN
fnp-5809	93	29	chose	choose	VERB
fnp-5809	93	30	a	a	DET
fnp-5809	93	31	complex	complex	ADJ
fnp-5809	93	32	study	study	NOUN
fnp-5809	93	33	design	design	NOUN
fnp-5809	93	34	including	include	VERB
fnp-5809	93	35	single	single	ADJ
fnp-5809	93	36	cell	cell	NOUN
fnp-5809	93	37	rna	rna	NOUN
fnp-5809	93	38	sequencing	sequencing	NOUN
fnp-5809	93	39	(	(	PUNCT
fnp-5809	93	40	scrnaseq	scrnaseq	NOUN
fnp-5809	93	41	)	)	PUNCT
fnp-5809	93	42	as	as	ADV
fnp-5809	93	43	well	well	ADV
fnp-5809	93	44	as	as	ADP
fnp-5809	93	45	genetic	genetic	ADJ
fnp-5809	93	46	and	and	CCONJ
fnp-5809	93	47	humanized	humanize	VERB
fnp-5809	93	48	mouse	mouse	NOUN
fnp-5809	93	49	models	model	NOUN
fnp-5809	93	50	approaches	approach	VERB
fnp-5809	93	51	[	[	X
fnp-5809	93	52	evans	evans	PROPN
fnp-5809	93	53	et	et	PROPN
fnp-5809	93	54	al	al	PROPN
fnp-5809	93	55	.	.	PROPN
fnp-5809	93	56	,	,	PUNCT
fnp-5809	93	57	2023	2023	NUM
fnp-5809	93	58	]	]	PUNCT
fnp-5809	93	59	.	.	PUNCT
fnp-5809	94	1	in	in	ADP
fnp-5809	94	2	a	a	DET
fnp-5809	94	3	murine	murine	ADJ
fnp-5809	94	4	breast	breast	NOUN
fnp-5809	94	5	carcinoma	carcinoma	NOUN
fnp-5809	94	6	brain	brain	NOUN
fnp-5809	94	7	metastasis	metastasis	NOUN
fnp-5809	94	8	model	model	NOUN
fnp-5809	94	9	in	in	ADP
fnp-5809	94	10	which	which	PRON
fnp-5809	94	11	intracardiac	intracardiac	VERB
fnp-5809	94	12	injection	injection	NOUN
fnp-5809	94	13	of	of	ADP
fnp-5809	94	14	tumor	tumor	NOUN
fnp-5809	94	15	cells	cell	NOUN
fnp-5809	94	16	led	lead	VERB
fnp-5809	94	17	to	to	ADP
fnp-5809	94	18	brain	brain	NOUN
fnp-5809	94	19	metastasis	metastasis	NOUN
fnp-5809	94	20	formation	formation	NOUN
fnp-5809	94	21	,	,	PUNCT
fnp-5809	94	22	scrnaseq	scrnaseq	PROPN
fnp-5809	94	23	revealed	reveal	VERB
fnp-5809	94	24	stable	stable	ADJ
fnp-5809	94	25	pro	pro	ADJ
fnp-5809	94	26	-	-	ADJ
fnp-5809	94	27	inflammatory	inflammatory	ADJ
fnp-5809	94	28	expression	expression	NOUN
fnp-5809	94	29	signatures	signature	NOUN
fnp-5809	94	30	related	relate	VERB
fnp-5809	94	31	to	to	PART
fnp-5809	94	32	cytokine	cytokine	VERB
fnp-5809	94	33	production	production	NOUN
fnp-5809	94	34	,	,	PUNCT
fnp-5809	94	35	antigen	antigen	NOUN
fnp-5809	94	36	processing	processing	NOUN
fnp-5809	94	37	and	and	CCONJ
fnp-5809	94	38	presentation	presentation	NOUN
fnp-5809	94	39	,	,	PUNCT
fnp-5809	94	40	and	and	CCONJ
fnp-5809	94	41	interferon	interferon	ADJ
fnp-5809	94	42	-	-	PUNCT
fnp-5809	94	43	beta	beta	NOUN
fnp-5809	94	44	responses	response	NOUN
fnp-5809	94	45	.	.	PUNCT
fnp-5809	95	1	as	as	SCONJ
fnp-5809	95	2	this	this	DET
fnp-5809	95	3	signature	signature	NOUN
fnp-5809	95	4	was	be	AUX
fnp-5809	95	5	microglia	microglia	ADJ
fnp-5809	95	6	-	-	ADJ
fnp-5809	95	7	specific	specific	ADJ
fnp-5809	95	8	and	and	CCONJ
fnp-5809	95	9	only	only	ADV
fnp-5809	95	10	encountered	encounter	VERB
fnp-5809	95	11	upon	upon	SCONJ
fnp-5809	95	12	brain	brain	NOUN
fnp-5809	95	13	metastasis	metastasis	NOUN
fnp-5809	95	14	formation	formation	NOUN
fnp-5809	95	15	,	,	PUNCT
fnp-5809	95	16	the	the	DET
fnp-5809	95	17	authors	author	NOUN
fnp-5809	95	18	hypothesized	hypothesize	VERB
fnp-5809	95	19	that	that	SCONJ
fnp-5809	95	20	these	these	DET
fnp-5809	95	21	transcriptional	transcriptional	ADJ
fnp-5809	95	22	changes	change	NOUN
fnp-5809	95	23	were	be	AUX
fnp-5809	95	24	related	relate	VERB
fnp-5809	95	25	to	to	ADP
fnp-5809	95	26	tumor	tumor	NOUN
fnp-5809	95	27	cell	cell	NOUN
fnp-5809	95	28	sensing	sense	VERB
fnp-5809	95	29	and	and	CCONJ
fnp-5809	95	30	pathological	pathological	ADJ
fnp-5809	95	31	tissue	tissue	NOUN
fnp-5809	95	32	alterations	alteration	NOUN
fnp-5809	95	33	.	.	PUNCT
fnp-5809	96	1	an	an	DET
fnp-5809	96	2	experimental	experimental	ADJ
fnp-5809	96	3	depletion	depletion	NOUN
fnp-5809	96	4	of	of	ADP
fnp-5809	96	5	microglial	microglial	ADJ
fnp-5809	96	6	cells	cell	NOUN
fnp-5809	96	7	using	use	VERB
fnp-5809	96	8	a	a	DET
fnp-5809	96	9	genetic	genetic	ADJ
fnp-5809	96	10	model	model	NOUN
fnp-5809	96	11	with	with	ADP
fnp-5809	96	12	deletion	deletion	NOUN
fnp-5809	96	13	of	of	ADP
fnp-5809	96	14	a	a	DET
fnp-5809	96	15	key	key	ADJ
fnp-5809	96	16	super	super	NOUN
fnp-5809	96	17	-	-	NOUN
fnp-5809	96	18	enhancer	enhancer	NOUN
fnp-5809	96	19	in	in	ADP
fnp-5809	96	20	the	the	DET
fnp-5809	96	21	csf1r	csf1r	PROPN
fnp-5809	96	22	locus	locus	NOUN
fnp-5809	96	23	was	be	AUX
fnp-5809	96	24	associated	associate	VERB
fnp-5809	96	25	with	with	ADP
fnp-5809	96	26	enhanced	enhanced	ADJ
fnp-5809	96	27	metastasis	metastasis	NOUN
fnp-5809	96	28	formation	formation	NOUN
fnp-5809	96	29	and	and	CCONJ
fnp-5809	96	30	reduced	reduced	ADJ
fnp-5809	96	31	survival	survival	NOUN
fnp-5809	96	32	rates	rate	NOUN
fnp-5809	96	33	.	.	PUNCT
fnp-5809	97	1	mechanistically	mechanistically	ADV
fnp-5809	97	2	,	,	PUNCT
fnp-5809	97	3	the	the	DET
fnp-5809	97	4	authors	author	NOUN
fnp-5809	97	5	showed	show	VERB
fnp-5809	97	6	that	that	SCONJ
fnp-5809	97	7	in	in	ADP
fnp-5809	97	8	the	the	DET
fnp-5809	97	9	context	context	NOUN
fnp-5809	97	10	of	of	ADP
fnp-5809	97	11	brain	brain	NOUN
fnp-5809	97	12	metastasis	metastasis	NOUN
fnp-5809	97	13	formation	formation	NOUN
fnp-5809	97	14	,	,	PUNCT
fnp-5809	97	15	microglial	microglial	ADJ
fnp-5809	97	16	cells	cell	NOUN
fnp-5809	97	17	activate	activate	VERB
fnp-5809	97	18	nk	nk	PROPN
fnp-5809	97	19	/	/	SYM
fnp-5809	97	20	nkt	nkt	PROPN
fnp-5809	97	21	and	and	CCONJ
fnp-5809	97	22	cd8	cd8	PROPN
fnp-5809	97	23	+	+	PROPN
fnp-5809	97	24	t	t	NOUN
fnp-5809	97	25	cells	cell	NOUN
fnp-5809	97	26	,	,	PUNCT
fnp-5809	97	27	while	while	SCONJ
fnp-5809	97	28	attracting	attract	VERB
fnp-5809	97	29	relatively	relatively	ADV
fnp-5809	97	30	less	less	ADV
fnp-5809	97	31	immunosuppressive	immunosuppressive	ADJ
fnp-5809	97	32	t	t	NOUN
fnp-5809	97	33	regulatory	regulatory	ADJ
fnp-5809	97	34	cells	cell	NOUN
fnp-5809	97	35	.	.	PUNCT
fnp-5809	98	1	of	of	ADP
fnp-5809	98	2	note	note	NOUN
fnp-5809	98	3	,	,	PUNCT
fnp-5809	98	4	experimental	experimental	ADJ
fnp-5809	98	5	depletion	depletion	NOUN
fnp-5809	98	6	of	of	ADP
fnp-5809	98	7	effector	effector	NOUN
fnp-5809	98	8	t	t	PROPN
fnp-5809	98	9	cells	cell	NOUN
fnp-5809	98	10	led	lead	VERB
fnp-5809	98	11	to	to	ADP
fnp-5809	98	12	reduced	reduce	VERB
fnp-5809	98	13	antigen	antigen	ADJ
fnp-5809	98	14	presentation	presentation	NOUN
fnp-5809	98	15	and	and	CCONJ
fnp-5809	98	16	ifn	ifn	ADJ
fnp-5809	98	17	response	response	NOUN
fnp-5809	98	18	in	in	ADP
fnp-5809	98	19	microglial	microglial	ADJ
fnp-5809	98	20	cells	cell	NOUN
fnp-5809	98	21	,	,	PUNCT
fnp-5809	98	22	suggesting	suggest	VERB
fnp-5809	98	23	that	that	SCONJ
fnp-5809	98	24	only	only	ADV
fnp-5809	98	25	the	the	DET
fnp-5809	98	26	orchestrated	orchestrated	ADJ
fnp-5809	98	27	interaction	interaction	NOUN
fnp-5809	98	28	between	between	ADP
fnp-5809	98	29	both	both	DET
fnp-5809	98	30	cell	cell	NOUN
fnp-5809	98	31	types	type	NOUN
fnp-5809	98	32	enables	enable	VERB
fnp-5809	98	33	their	their	PRON
fnp-5809	98	34	full	full	ADJ
fnp-5809	98	35	antitumoral	antitumoral	ADJ
fnp-5809	98	36	capacity	capacity	NOUN
fnp-5809	98	37	(	(	PUNCT
fnp-5809	98	38	figure	figure	NOUN
fnp-5809	98	39	4	4	NUM
fnp-5809	98	40	)	)	PUNCT
fnp-5809	98	41	.	.	PUNCT
fnp-5809	99	1	the	the	DET
fnp-5809	99	2	antitumoral	antitumoral	ADJ
fnp-5809	99	3	responses	response	NOUN
fnp-5809	99	4	were	be	AUX
fnp-5809	99	5	conserved	conserve	VERB
fnp-5809	99	6	in	in	ADP
fnp-5809	99	7	an	an	DET
fnp-5809	99	8	additional	additional	ADJ
fnp-5809	99	9	experimental	experimental	ADJ
fnp-5809	99	10	mouse	mouse	NOUN
fnp-5809	99	11	model	model	NOUN
fnp-5809	99	12	with	with	ADP
fnp-5809	99	13	human	human	ADJ
fnp-5809	99	14	microglial	microglial	ADJ
fnp-5809	99	15	cells	cell	NOUN
fnp-5809	99	16	.	.	PUNCT
fnp-5809	100	1	the	the	DET
fnp-5809	100	2	authors	author	NOUN
fnp-5809	100	3	reanalyzed	reanalyze	VERB
fnp-5809	100	4	data	datum	NOUN
fnp-5809	100	5	from	from	ADP
fnp-5809	100	6	an	an	DET
fnp-5809	100	7	rna	rna	NOUN
fnp-5809	100	8	sequencing	sequencing	NOUN
fnp-5809	100	9	study	study	NOUN
fnp-5809	100	10	from	from	ADP
fnp-5809	100	11	human	human	ADJ
fnp-5809	100	12	breast	breast	NOUN
fnp-5809	100	13	cancer	cancer	NOUN
fnp-5809	100	14	brain	brain	NOUN
fnp-5809	100	15	metastasis	metastasis	NOUN
fnp-5809	100	16	patients	patient	NOUN
fnp-5809	100	17	[	[	X
fnp-5809	100	18	varešlija	varešlija	X
fnp-5809	100	19	et	et	PROPN
fnp-5809	100	20	al	al	PROPN
fnp-5809	100	21	.	.	PROPN
fnp-5809	100	22	,	,	PUNCT
fnp-5809	100	23	2019	2019	NUM
fnp-5809	100	24	]	]	PUNCT
fnp-5809	100	25	.	.	PUNCT
fnp-5809	101	1	in	in	ADP
fnp-5809	101	2	line	line	NOUN
fnp-5809	101	3	with	with	ADP
fnp-5809	101	4	their	their	PRON
fnp-5809	101	5	findings	finding	NOUN
fnp-5809	101	6	and	and	CCONJ
fnp-5809	101	7	hypotheses	hypothesis	NOUN
fnp-5809	101	8	,	,	PUNCT
fnp-5809	101	9	this	this	DET
fnp-5809	101	10	patient	patient	ADJ
fnp-5809	101	11	cohort	cohort	NOUN
fnp-5809	101	12	demonstrated	demonstrate	VERB
fnp-5809	101	13	significantly	significantly	ADV
fnp-5809	101	14	longer	long	ADJ
fnp-5809	101	15	survival	survival	NOUN
fnp-5809	101	16	rates	rate	NOUN
fnp-5809	101	17	if	if	SCONJ
fnp-5809	101	18	breast	breast	NOUN
fnp-5809	101	19	cancer	cancer	NOUN
fnp-5809	101	20	brain	brain	NOUN
fnp-5809	101	21	metastases	metastasis	NOUN
fnp-5809	101	22	were	be	AUX
fnp-5809	101	23	associated	associate	VERB
fnp-5809	101	24	with	with	ADP
fnp-5809	101	25	a	a	DET
fnp-5809	101	26	high	high	ADJ
fnp-5809	101	27	expression	expression	NOUN
fnp-5809	101	28	of	of	ADP
fnp-5809	101	29	canonical	canonical	ADJ
fnp-5809	101	30	microglial	microglial	ADJ
fnp-5809	101	31	markers	marker	NOUN
fnp-5809	101	32	indicating	indicate	VERB
fnp-5809	101	33	a	a	DET
fnp-5809	101	34	higher	high	ADJ
fnp-5809	101	35	tumor	tumor	NOUN
fnp-5809	101	36	infiltration	infiltration	NOUN
fnp-5809	101	37	by	by	ADP
fnp-5809	101	38	microglial	microglial	ADJ
fnp-5809	101	39	cells	cell	NOUN
fnp-5809	101	40	.	.	PUNCT
fnp-5809	102	1	although	although	SCONJ
fnp-5809	102	2	still	still	ADV
fnp-5809	102	3	many	many	ADJ
fnp-5809	102	4	scientific	scientific	ADJ
fnp-5809	102	5	papers	paper	NOUN
fnp-5809	102	6	stress	stress	VERB
fnp-5809	102	7	a	a	DET
fnp-5809	102	8	pro	pro	ADJ
fnp-5809	102	9	-	-	ADJ
fnp-5809	102	10	tumorigenic	tumorigenic	ADJ
fnp-5809	102	11	role	role	NOUN
fnp-5809	102	12	of	of	ADP
fnp-5809	102	13	microglial	microglial	ADJ
fnp-5809	102	14	cells	cell	NOUN
fnp-5809	102	15	in	in	ADP
fnp-5809	102	16	primary	primary	ADJ
fnp-5809	102	17	and	and	CCONJ
fnp-5809	102	18	secondary	secondary	ADJ
fnp-5809	102	19	brain	brain	NOUN
fnp-5809	102	20	tumors	tumor	NOUN
fnp-5809	102	21	,	,	PUNCT
fnp-5809	102	22	the	the	DET
fnp-5809	102	23	findings	finding	NOUN
fnp-5809	102	24	of	of	ADP
fnp-5809	102	25	the	the	DET
fnp-5809	102	26	present	present	ADJ
fnp-5809	102	27	study	study	NOUN
fnp-5809	102	28	are	be	AUX
fnp-5809	102	29	also	also	ADV
fnp-5809	102	30	in	in	ADP
fnp-5809	102	31	line	line	NOUN
fnp-5809	102	32	with	with	ADP
fnp-5809	102	33	some	some	DET
fnp-5809	102	34	human	human	ADJ
fnp-5809	102	35	tissue	tissue	NOUN
fnp-5809	102	36	-	-	PUNCT
fnp-5809	102	37	based	base	VERB
fnp-5809	102	38	studies	study	NOUN
fnp-5809	102	39	describing	describe	VERB
fnp-5809	102	40	a	a	DET
fnp-5809	102	41	beneficial	beneficial	ADJ
fnp-5809	102	42	contribution	contribution	NOUN
fnp-5809	102	43	of	of	ADP
fnp-5809	102	44	microglial	microglial	ADJ
fnp-5809	102	45	cells	cell	NOUN
fnp-5809	102	46	to	to	ADP
fnp-5809	102	47	prolonged	prolonged	ADJ
fnp-5809	102	48	patient	patient	ADJ
fnp-5809	102	49	survival	survival	NOUN
fnp-5809	102	50	in	in	ADP
fnp-5809	102	51	glioblastoma	glioblastoma	NOUN
fnp-5809	102	52	[	[	X
fnp-5809	102	53	zeiner	zeiner	NOUN
fnp-5809	102	54	et	et	PROPN
fnp-5809	102	55	al	al	PROPN
fnp-5809	102	56	.	.	PROPN
fnp-5809	102	57	,	,	PUNCT
fnp-5809	102	58	2019	2019	NUM
fnp-5809	102	59	]	]	PUNCT
fnp-5809	102	60	.	.	PUNCT
fnp-5809	103	1	figure	figure	VERB
fnp-5809	103	2	4	4	NUM
fnp-5809	103	3	:	:	PUNCT
fnp-5809	103	4	proinflammatory	proinflammatory	ADJ
fnp-5809	103	5	microglial	microglial	ADJ
fnp-5809	103	6	signature	signature	NOUN
fnp-5809	103	7	associated	associate	VERB
fnp-5809	103	8	with	with	ADP
fnp-5809	103	9	activation	activation	NOUN
fnp-5809	103	10	of	of	ADP
fnp-5809	103	11	cytotoxic	cytotoxic	ADJ
fnp-5809	103	12	t	t	PROPN
fnp-5809	103	13	and	and	CCONJ
fnp-5809	103	14	nk	nk	PROPN
fnp-5809	103	15	cells	cell	NOUN
fnp-5809	103	16	and	and	CCONJ
fnp-5809	103	17	inhibition	inhibition	NOUN
fnp-5809	103	18	of	of	ADP
fnp-5809	103	19	regulatory	regulatory	ADJ
fnp-5809	103	20	t	t	NOUN
fnp-5809	103	21	cells	cell	NOUN
fnp-5809	103	22	inhibiting	inhibit	VERB
fnp-5809	103	23	brain	brain	NOUN
fnp-5809	103	24	metastasis	metastasis	NOUN
fnp-5809	103	25	growth	growth	NOUN
fnp-5809	103	26	.	.	PUNCT
fnp-5809	104	1	5	5	X
fnp-5809	104	2	.	.	X
fnp-5809	104	3	proposal	proposal	NOUN
fnp-5809	104	4	of	of	ADP
fnp-5809	104	5	a	a	DET
fnp-5809	104	6	new	new	ADJ
fnp-5809	104	7	tumor	tumor	NOUN
fnp-5809	104	8	entity	entity	NOUN
fnp-5809	104	9	:	:	PUNCT
fnp-5809	104	10	glioneuronal	glioneuronal	ADJ
fnp-5809	104	11	tumor	tumor	NOUN
fnp-5809	104	12	with	with	ADP
fnp-5809	104	13	atrx	atrx	PROPN
fnp-5809	104	14	alteration	alteration	NOUN
fnp-5809	104	15	,	,	PUNCT
fnp-5809	104	16	ntrk	ntrk	NOUN
fnp-5809	104	17	gene	gene	NOUN
fnp-5809	104	18	fusion	fusion	NOUN
fnp-5809	104	19	and	and	CCONJ
fnp-5809	104	20	anaplastic	anaplastic	ADJ
fnp-5809	104	21	features	feature	NOUN
fnp-5809	104	22	(	(	PUNCT
fnp-5809	104	23	gtaka	gtaka	NOUN
fnp-5809	104	24	)	)	PUNCT
fnp-5809	105	1	[	[	X
fnp-5809	105	2	bogumil	bogumil	PROPN
fnp-5809	105	3	et	et	PROPN
fnp-5809	105	4	al	al	PROPN
fnp-5809	105	5	.	.	PROPN
fnp-5809	105	6	,	,	PUNCT
fnp-5809	105	7	2023	2023	NUM
fnp-5809	105	8	]	]	PUNCT
fnp-5809	105	9	.	.	PUNCT
fnp-5809	106	1	although	although	SCONJ
fnp-5809	106	2	glioneuronal	glioneuronal	ADJ
fnp-5809	106	3	neoplasms	neoplasm	NOUN
fnp-5809	106	4	constitute	constitute	VERB
fnp-5809	106	5	a	a	DET
fnp-5809	106	6	fairly	fairly	ADV
fnp-5809	106	7	rare	rare	ADJ
fnp-5809	106	8	group	group	NOUN
fnp-5809	106	9	of	of	ADP
fnp-5809	106	10	brain	brain	NOUN
fnp-5809	106	11	tumors	tumor	NOUN
fnp-5809	106	12	,	,	PUNCT
fnp-5809	106	13	new	new	ADJ
fnp-5809	106	14	entities	entity	NOUN
fnp-5809	106	15	belonging	belong	VERB
fnp-5809	106	16	to	to	ADP
fnp-5809	106	17	this	this	DET
fnp-5809	106	18	group	group	NOUN
fnp-5809	106	19	are	be	AUX
fnp-5809	106	20	constantly	constantly	ADV
fnp-5809	106	21	emerging	emerge	VERB
fnp-5809	106	22	,	,	PUNCT
fnp-5809	106	23	mainly	mainly	ADV
fnp-5809	106	24	due	due	ADP
fnp-5809	106	25	to	to	ADP
fnp-5809	106	26	the	the	DET
fnp-5809	106	27	increasing	increase	VERB
fnp-5809	106	28	use	use	NOUN
fnp-5809	106	29	of	of	ADP
fnp-5809	106	30	molecular	molecular	ADJ
fnp-5809	106	31	methods	method	NOUN
fnp-5809	106	32	and	and	CCONJ
fnp-5809	106	33	respective	respective	ADJ
fnp-5809	106	34	analyses	analysis	NOUN
fnp-5809	106	35	in	in	ADP
fnp-5809	106	36	larger	large	ADJ
fnp-5809	106	37	,	,	PUNCT
fnp-5809	106	38	centralized	centralized	ADJ
fnp-5809	106	39	databases	database	NOUN
fnp-5809	106	40	that	that	PRON
fnp-5809	106	41	allow	allow	VERB
fnp-5809	106	42	for	for	ADP
fnp-5809	106	43	a	a	DET
fnp-5809	106	44	faster	fast	ADJ
fnp-5809	106	45	collection	collection	NOUN
fnp-5809	106	46	of	of	ADP
fnp-5809	106	47	isolated	isolated	ADJ
fnp-5809	106	48	rare	rare	ADJ
fnp-5809	106	49	cases	case	NOUN
fnp-5809	106	50	.	.	PUNCT
fnp-5809	107	1	dna	dna	PROPN
fnp-5809	107	2	methylation	methylation	NOUN
fnp-5809	107	3	profiling	profiling	NOUN
fnp-5809	107	4	revealed	reveal	VERB
fnp-5809	107	5	a	a	DET
fnp-5809	107	6	distinct	distinct	ADJ
fnp-5809	107	7	new	new	ADJ
fnp-5809	107	8	group	group	NOUN
fnp-5809	107	9	of	of	ADP
fnp-5809	107	10	20	20	NUM
fnp-5809	107	11	cases	case	NOUN
fnp-5809	107	12	(	(	PUNCT
fnp-5809	107	13	median	median	ADJ
fnp-5809	107	14	age	age	NOUN
fnp-5809	107	15	:	:	PUNCT
fnp-5809	107	16	19	19	NUM
fnp-5809	107	17	years	year	NOUN
fnp-5809	107	18	)	)	PUNCT
fnp-5809	107	19	of	of	ADP
fnp-5809	107	20	mainly	mainly	ADV
fnp-5809	107	21	supratentorial	supratentorial	ADJ
fnp-5809	107	22	(	(	PUNCT
fnp-5809	107	23	84	84	NUM
fnp-5809	107	24	 	 	SPACE
fnp-5809	107	25	%	%	NOUN
fnp-5809	107	26	)	)	PUNCT
fnp-5809	107	27	location	location	NOUN
fnp-5809	107	28	with	with	ADP
fnp-5809	107	29	histologically	histologically	ADV
fnp-5809	107	30	glioneuronal	glioneuronal	ADJ
fnp-5809	107	31	features	feature	NOUN
fnp-5809	107	32	as	as	ADP
fnp-5809	107	33	compared	compare	VERB
fnp-5809	107	34	to	to	ADP
fnp-5809	107	35	a	a	DET
fnp-5809	107	36	reference	reference	NOUN
fnp-5809	107	37	cohort	cohort	NOUN
fnp-5809	107	38	of	of	ADP
fnp-5809	107	39	more	more	ADJ
fnp-5809	107	40	than	than	ADP
fnp-5809	107	41	100,000	100,000	NUM
fnp-5809	107	42	patients	patient	NOUN
fnp-5809	107	43	.	.	PUNCT
fnp-5809	108	1	in	in	ADP
fnp-5809	108	2	a	a	DET
fnp-5809	108	3	more	more	ADV
fnp-5809	108	4	fine	fine	ADV
fnp-5809	108	5	-	-	PUNCT
fnp-5809	108	6	tuned	tune	VERB
fnp-5809	108	7	approach	approach	NOUN
fnp-5809	108	8	comparing	compare	VERB
fnp-5809	108	9	those	those	DET
fnp-5809	108	10	cases	case	NOUN
fnp-5809	108	11	with	with	ADP
fnp-5809	108	12	a	a	DET
fnp-5809	108	13	reference	reference	NOUN
fnp-5809	108	14	cohort	cohort	NOUN
fnp-5809	108	15	of	of	ADP
fnp-5809	108	16	718	718	NUM
fnp-5809	108	17	neuroepithelial	neuroepithelial	ADJ
fnp-5809	108	18	tumors	tumor	NOUN
fnp-5809	108	19	,	,	PUNCT
fnp-5809	108	20	unsupervised	unsupervised	ADJ
fnp-5809	108	21	,	,	PUNCT
fnp-5809	108	22	non	non	ADJ
fnp-5809	108	23	-	-	ADJ
fnp-5809	108	24	linear	linear	ADJ
fnp-5809	108	25	t	t	NOUN
fnp-5809	108	26	-	-	PUNCT
fnp-5809	108	27	distributed	distribute	VERB
fnp-5809	108	28	stochastic	stochastic	ADJ
fnp-5809	108	29	neighbor	neighbor	NOUN
fnp-5809	108	30	embedding	embed	VERB
fnp-5809	108	31	(	(	PUNCT
fnp-5809	108	32	t	t	PROPN
fnp-5809	108	33	-	-	PUNCT
fnp-5809	108	34	sne	sne	NOUN
fnp-5809	108	35	)	)	PUNCT
fnp-5809	108	36	projection	projection	NOUN
fnp-5809	108	37	,	,	PUNCT
fnp-5809	108	38	this	this	DET
fnp-5809	108	39	distinct	distinct	ADJ
fnp-5809	108	40	subgroup	subgroup	NOUN
fnp-5809	108	41	could	could	AUX
fnp-5809	108	42	be	be	AUX
fnp-5809	108	43	confirmed	confirm	VERB
fnp-5809	108	44	.	.	PUNCT
fnp-5809	109	1	further	further	ADJ
fnp-5809	109	2	detailed	detailed	ADJ
fnp-5809	109	3	neuropathological	neuropathological	ADJ
fnp-5809	109	4	and	and	CCONJ
fnp-5809	109	5	molecular	molecular	ADJ
fnp-5809	109	6	pathological	pathological	ADJ
fnp-5809	109	7	analyses	analysis	NOUN
fnp-5809	109	8	could	could	AUX
fnp-5809	109	9	be	be	AUX
fnp-5809	109	10	performed	perform	VERB
fnp-5809	109	11	in	in	ADP
fnp-5809	109	12	16	16	NUM
fnp-5809	109	13	out	out	ADP
fnp-5809	109	14	of	of	ADP
fnp-5809	109	15	those	those	DET
fnp-5809	109	16	20	20	NUM
fnp-5809	109	17	tumors	tumor	NOUN
fnp-5809	109	18	.	.	PUNCT
fnp-5809	110	1	all	all	DET
fnp-5809	110	2	tumors	tumor	NOUN
fnp-5809	110	3	showed	show	VERB
fnp-5809	110	4	alterations	alteration	NOUN
fnp-5809	110	5	of	of	ADP
fnp-5809	110	6	atrx	atrx	PROPN
fnp-5809	110	7	,	,	PUNCT
fnp-5809	110	8	assessed	assess	VERB
fnp-5809	110	9	by	by	ADP
fnp-5809	110	10	dna	dna	NOUN
fnp-5809	110	11	sequencing	sequencing	NOUN
fnp-5809	110	12	and/or	and/or	CCONJ
fnp-5809	110	13	immunohistochemistry	immunohistochemistry	NOUN
fnp-5809	110	14	.	.	PUNCT
fnp-5809	111	1	in	in	ADP
fnp-5809	111	2	addition	addition	NOUN
fnp-5809	111	3	,	,	PUNCT
fnp-5809	111	4	all	all	DET
fnp-5809	111	5	cases	case	NOUN
fnp-5809	111	6	showed	show	VERB
fnp-5809	111	7	a	a	DET
fnp-5809	111	8	potentially	potentially	ADV
fnp-5809	111	9	druggable	druggable	ADJ
fnp-5809	111	10	gene	gene	NOUN
fnp-5809	111	11	fusion	fusion	NOUN
fnp-5809	111	12	involving	involve	VERB
fnp-5809	111	13	members	member	NOUN
fnp-5809	111	14	of	of	ADP
fnp-5809	111	15	the	the	DET
fnp-5809	111	16	receptor	receptor	NOUN
fnp-5809	111	17	tyrosine	tyrosine	NOUN
fnp-5809	111	18	-	-	PUNCT
fnp-5809	111	19	kinase	kinase	PROPN
fnp-5809	111	20	family	family	NOUN
fnp-5809	111	21	,	,	PUNCT
fnp-5809	111	22	mainly	mainly	ADV
fnp-5809	111	23	ntrk1	ntrk1	PROPN
fnp-5809	111	24	-	-	PUNCT
fnp-5809	111	25	3	3	NUM
fnp-5809	111	26	.	.	PUNCT
fnp-5809	112	1	in	in	ADP
fnp-5809	112	2	slightly	slightly	ADV
fnp-5809	112	3	more	more	ADJ
fnp-5809	112	4	than	than	ADP
fnp-5809	112	5	half	half	NOUN
fnp-5809	112	6	of	of	ADP
fnp-5809	112	7	the	the	DET
fnp-5809	112	8	patients	patient	NOUN
fnp-5809	112	9	,	,	PUNCT
fnp-5809	112	10	homozygous	homozygous	ADJ
fnp-5809	112	11	deletion	deletion	NOUN
fnp-5809	112	12	of	of	ADP
fnp-5809	112	13	cdkn2a	cdkn2a	PROPN
fnp-5809	112	14	/	/	SYM
fnp-5809	112	15	b	b	PROPN
fnp-5809	112	16	was	be	AUX
fnp-5809	112	17	observed	observe	VERB
fnp-5809	112	18	.	.	PUNCT
fnp-5809	113	1	the	the	DET
fnp-5809	113	2	neuropathological	neuropathological	ADJ
fnp-5809	113	3	assessment	assessment	NOUN
fnp-5809	113	4	of	of	ADP
fnp-5809	113	5	those	those	DET
fnp-5809	113	6	tumors	tumor	NOUN
fnp-5809	113	7	showed	show	VERB
fnp-5809	113	8	isomorphic	isomorphic	ADJ
fnp-5809	113	9	,	,	PUNCT
fnp-5809	113	10	round	round	ADJ
fnp-5809	113	11	,	,	PUNCT
fnp-5809	113	12	often	often	ADV
fnp-5809	113	13	condensed	condense	VERB
fnp-5809	113	14	nuclei	nucleus	NOUN
fnp-5809	113	15	with	with	ADP
fnp-5809	113	16	perinuclear	perinuclear	ADJ
fnp-5809	113	17	clearing	clearing	NOUN
fnp-5809	113	18	,	,	PUNCT
fnp-5809	113	19	prominent	prominent	ADJ
fnp-5809	113	20	mitotic	mitotic	ADJ
fnp-5809	113	21	indices	index	NOUN
fnp-5809	113	22	and	and	CCONJ
fnp-5809	113	23	vascular	vascular	ADJ
fnp-5809	113	24	proliferations	proliferation	NOUN
fnp-5809	113	25	.	.	PUNCT
fnp-5809	114	1	for	for	ADP
fnp-5809	114	2	this	this	DET
fnp-5809	114	3	new	new	ADJ
fnp-5809	114	4	entity	entity	NOUN
fnp-5809	114	5	,	,	PUNCT
fnp-5809	114	6	the	the	DET
fnp-5809	114	7	proposed	propose	VERB
fnp-5809	114	8	acronym	acronym	NOUN
fnp-5809	114	9	“	"	PUNCT
fnp-5809	114	10	gtaka	gtaka	NOUN
fnp-5809	114	11	”	"	PUNCT
fnp-5809	114	12	is	be	AUX
fnp-5809	114	13	composed	compose	VERB
fnp-5809	114	14	of	of	ADP
fnp-5809	114	15	its	its	PRON
fnp-5809	114	16	central	central	ADJ
fnp-5809	114	17	neuropathological	neuropathological	ADJ
fnp-5809	114	18	and	and	CCONJ
fnp-5809	114	19	molecular	molecular	ADJ
fnp-5809	114	20	features	feature	NOUN
fnp-5809	114	21	,	,	PUNCT
fnp-5809	114	22	namely	namely	ADV
fnp-5809	114	23	glioneuronal	glioneuronal	ADJ
fnp-5809	114	24	tumor	tumor	NOUN
fnp-5809	114	25	with	with	ADP
fnp-5809	114	26	atrx	atrx	PROPN
fnp-5809	114	27	alteration	alteration	NOUN
fnp-5809	114	28	,	,	PUNCT
fnp-5809	114	29	kinase	kinase	NOUN
fnp-5809	114	30	fusion	fusion	NOUN
fnp-5809	114	31	and	and	CCONJ
fnp-5809	114	32	anaplastic	anaplastic	ADJ
fnp-5809	114	33	features	feature	NOUN
fnp-5809	114	34	(	(	PUNCT
fnp-5809	114	35	table	table	NOUN
fnp-5809	114	36	1	1	NUM
fnp-5809	114	37	)	)	PUNCT
fnp-5809	114	38	.	.	PUNCT
fnp-5809	115	1	at	at	ADP
fnp-5809	115	2	the	the	DET
fnp-5809	115	3	current	current	ADJ
fnp-5809	115	4	stage	stage	NOUN
fnp-5809	115	5	,	,	PUNCT
fnp-5809	115	6	it	it	PRON
fnp-5809	115	7	is	be	AUX
fnp-5809	115	8	too	too	ADV
fnp-5809	115	9	early	early	ADJ
fnp-5809	115	10	to	to	PART
fnp-5809	115	11	provide	provide	VERB
fnp-5809	115	12	precise	precise	ADJ
fnp-5809	115	13	prognostic	prognostic	ADJ
fnp-5809	115	14	estimations	estimation	NOUN
fnp-5809	115	15	,	,	PUNCT
fnp-5809	115	16	however	however	ADV
fnp-5809	115	17	this	this	DET
fnp-5809	115	18	new	new	ADJ
fnp-5809	115	19	subgroup	subgroup	NOUN
fnp-5809	115	20	of	of	ADP
fnp-5809	115	21	glioneuronal	glioneuronal	ADJ
fnp-5809	115	22	tumors	tumor	NOUN
fnp-5809	115	23	with	with	ADP
fnp-5809	115	24	a	a	DET
fnp-5809	115	25	median	median	ADJ
fnp-5809	115	26	progression	progression	NOUN
fnp-5809	115	27	-	-	PUNCT
fnp-5809	115	28	free	free	ADJ
fnp-5809	115	29	survival	survival	NOUN
fnp-5809	115	30	of	of	ADP
fnp-5809	115	31	only	only	ADV
fnp-5809	115	32	12.5	12.5	NUM
fnp-5809	115	33	months	month	NOUN
fnp-5809	115	34	seems	seem	VERB
fnp-5809	115	35	to	to	PART
fnp-5809	115	36	be	be	AUX
fnp-5809	115	37	clearly	clearly	ADV
fnp-5809	115	38	more	more	ADV
fnp-5809	115	39	aggressive	aggressive	ADJ
fnp-5809	115	40	than	than	ADP
fnp-5809	115	41	many	many	ADJ
fnp-5809	115	42	other	other	ADJ
fnp-5809	115	43	,	,	PUNCT
fnp-5809	115	44	already	already	ADV
fnp-5809	115	45	established	establish	VERB
fnp-5809	115	46	glioneuronal	glioneuronal	ADJ
fnp-5809	115	47	tumor	tumor	NOUN
fnp-5809	115	48	entities	entity	NOUN
fnp-5809	115	49	.	.	PUNCT
fnp-5809	116	1	table	table	NOUN
fnp-5809	116	2	1	1	NUM
fnp-5809	116	3	:	:	PUNCT
fnp-5809	116	4	proposition	proposition	NOUN
fnp-5809	116	5	of	of	ADP
fnp-5809	116	6	diagnostic	diagnostic	ADJ
fnp-5809	116	7	criteria	criterion	NOUN
fnp-5809	116	8	for	for	ADP
fnp-5809	116	9	glioneuronal	glioneuronal	ADJ
fnp-5809	116	10	tumor	tumor	NOUN
fnp-5809	116	11	with	with	ADP
fnp-5809	116	12	atrx	atrx	NOUN
fnp-5809	116	13	alterations	alteration	NOUN
fnp-5809	116	14	,	,	PUNCT
fnp-5809	116	15	kinase	kinase	NOUN
fnp-5809	116	16	fusion	fusion	NOUN
fnp-5809	116	17	and	and	CCONJ
fnp-5809	116	18	anaplastic	anaplastic	ADJ
fnp-5809	116	19	features	feature	NOUN
fnp-5809	116	20	(	(	PUNCT
fnp-5809	116	21	“	"	PUNCT
fnp-5809	116	22	gtaka	gtaka	NOUN
fnp-5809	116	23	”	"	PUNCT
fnp-5809	116	24	)	)	PUNCT
fnp-5809	116	25	.	.	PUNCT
fnp-5809	117	1	6	6	X
fnp-5809	117	2	.	.	PUNCT
fnp-5809	117	3	“	"	PUNCT
fnp-5809	117	4	de	de	X
fnp-5809	117	5	novo	novo	NOUN
fnp-5809	117	6	replication	replication	NOUN
fnp-5809	117	7	repair	repair	NOUN
fnp-5809	117	8	deficient	deficient	ADJ
fnp-5809	117	9	glioblastoma	glioblastoma	NOUN
fnp-5809	117	10	,	,	PUNCT
fnp-5809	117	11	idh	idh	PROPN
fnp-5809	117	12	wildtype	wildtype	NOUN
fnp-5809	117	13	”	"	PUNCT
fnp-5809	117	14	:	:	PUNCT
fnp-5809	117	15	a	a	DET
fnp-5809	117	16	new	new	ADJ
fnp-5809	117	17	glioblastoma	glioblastoma	NOUN
fnp-5809	117	18	subtype	subtype	NOUN
fnp-5809	117	19	with	with	ADP
fnp-5809	117	20	implications	implication	NOUN
fnp-5809	117	21	for	for	ADP
fnp-5809	117	22	targeted	target	VERB
fnp-5809	117	23	treatment	treatment	NOUN
fnp-5809	117	24	[	[	X
fnp-5809	117	25	hadad	hadad	PROPN
fnp-5809	117	26	et	et	PROPN
fnp-5809	117	27	al	al	PROPN
fnp-5809	117	28	.	.	PROPN
fnp-5809	117	29	,	,	PUNCT
fnp-5809	117	30	2023	2023	NUM
fnp-5809	117	31	]	]	PUNCT
fnp-5809	117	32	.	.	PUNCT
fnp-5809	118	1	over	over	ADP
fnp-5809	118	2	decades	decade	NOUN
fnp-5809	118	3	,	,	PUNCT
fnp-5809	118	4	the	the	DET
fnp-5809	118	5	treatment	treatment	NOUN
fnp-5809	118	6	of	of	ADP
fnp-5809	118	7	glioblastoma	glioblastoma	NOUN
fnp-5809	118	8	patients	patient	NOUN
fnp-5809	118	9	consisted	consist	VERB
fnp-5809	118	10	of	of	ADP
fnp-5809	118	11	neurosurgical	neurosurgical	ADJ
fnp-5809	118	12	resection	resection	NOUN
fnp-5809	118	13	followed	follow	VERB
fnp-5809	118	14	by	by	ADP
fnp-5809	118	15	radio	radio	NOUN
fnp-5809	118	16	-	-	PUNCT
fnp-5809	118	17	chemotherapy	chemotherapy	NOUN
fnp-5809	118	18	and	and	CCONJ
fnp-5809	118	19	is	be	AUX
fnp-5809	118	20	,	,	PUNCT
fnp-5809	118	21	however	however	ADV
fnp-5809	118	22	,	,	PUNCT
fnp-5809	118	23	still	still	ADV
fnp-5809	118	24	associated	associate	VERB
fnp-5809	118	25	with	with	ADP
fnp-5809	118	26	a	a	DET
fnp-5809	118	27	detrimental	detrimental	ADJ
fnp-5809	118	28	prognosis	prognosis	NOUN
fnp-5809	118	29	.	.	PUNCT
fnp-5809	119	1	despite	despite	SCONJ
fnp-5809	119	2	a	a	DET
fnp-5809	119	3	multitude	multitude	NOUN
fnp-5809	119	4	of	of	ADP
fnp-5809	119	5	clinical	clinical	ADJ
fnp-5809	119	6	studies	study	NOUN
fnp-5809	119	7	,	,	PUNCT
fnp-5809	119	8	valid	valid	ADJ
fnp-5809	119	9	biomarkers	biomarker	NOUN
fnp-5809	119	10	for	for	ADP
fnp-5809	119	11	potential	potential	ADJ
fnp-5809	119	12	targeted	target	VERB
fnp-5809	119	13	therapies	therapy	NOUN
fnp-5809	119	14	are	be	AUX
fnp-5809	119	15	largely	largely	ADV
fnp-5809	119	16	lacking	lack	VERB
fnp-5809	119	17	[	[	PUNCT
fnp-5809	119	18	rodgers	rodger	NOUN
fnp-5809	119	19	et	et	PROPN
fnp-5809	119	20	al	al	PROPN
fnp-5809	119	21	.	.	PROPN
fnp-5809	119	22	,	,	PUNCT
fnp-5809	119	23	2024	2024	NUM
fnp-5809	119	24	]	]	PUNCT
fnp-5809	119	25	.	.	PUNCT
fnp-5809	120	1	therefore	therefore	ADV
fnp-5809	120	2	,	,	PUNCT
fnp-5809	120	3	it	it	PRON
fnp-5809	120	4	is	be	AUX
fnp-5809	120	5	highly	highly	ADV
fnp-5809	120	6	important	important	ADJ
fnp-5809	120	7	to	to	PART
fnp-5809	120	8	define	define	VERB
fnp-5809	120	9	glioblastoma	glioblastoma	NOUN
fnp-5809	120	10	subtypes	subtype	NOUN
fnp-5809	120	11	,	,	PUNCT
fnp-5809	120	12	even	even	ADV
fnp-5809	120	13	if	if	SCONJ
fnp-5809	120	14	they	they	PRON
fnp-5809	120	15	only	only	ADV
fnp-5809	120	16	occur	occur	VERB
fnp-5809	120	17	at	at	ADP
fnp-5809	120	18	low	low	ADJ
fnp-5809	120	19	percentages	percentage	NOUN
fnp-5809	120	20	,	,	PUNCT
fnp-5809	120	21	that	that	PRON
fnp-5809	120	22	might	might	AUX
fnp-5809	120	23	benefit	benefit	VERB
fnp-5809	120	24	from	from	ADP
fnp-5809	120	25	new	new	ADJ
fnp-5809	120	26	treatment	treatment	NOUN
fnp-5809	120	27	approaches	approach	NOUN
fnp-5809	120	28	.	.	PUNCT
fnp-5809	121	1	in	in	ADP
fnp-5809	121	2	a	a	DET
fnp-5809	121	3	recent	recent	ADJ
fnp-5809	121	4	larger	large	ADJ
fnp-5809	121	5	series	series	NOUN
fnp-5809	121	6	of	of	ADP
fnp-5809	121	7	459	459	NUM
fnp-5809	121	8	consecutive	consecutive	ADJ
fnp-5809	121	9	glioblastoma	glioblastoma	NOUN
fnp-5809	121	10	patients	patient	NOUN
fnp-5809	121	11	,	,	PUNCT
fnp-5809	121	12	9	9	NUM
fnp-5809	121	13	patients	patient	NOUN
fnp-5809	121	14	(	(	PUNCT
fnp-5809	121	15	2	2	NUM
fnp-5809	121	16	 	 	SPACE
fnp-5809	121	17	%	%	NOUN
fnp-5809	121	18	)	)	PUNCT
fnp-5809	121	19	with	with	ADP
fnp-5809	121	20	a	a	DET
fnp-5809	121	21	biallelic	biallelic	ADJ
fnp-5809	121	22	inactivation	inactivation	NOUN
fnp-5809	121	23	of	of	ADP
fnp-5809	121	24	a	a	DET
fnp-5809	121	25	canonical	canonical	ADJ
fnp-5809	121	26	mismatch	mismatch	NOUN
fnp-5809	121	27	repair	repair	NOUN
fnp-5809	121	28	gene	gene	NOUN
fnp-5809	121	29	(	(	PUNCT
fnp-5809	121	30	msh2	msh2	NOUN
fnp-5809	121	31	,	,	PUNCT
fnp-5809	121	32	msh6	msh6	NOUN
fnp-5809	121	33	or	or	CCONJ
fnp-5809	121	34	mlh1	mlh1	PROPN
fnp-5809	121	35	)	)	PUNCT
fnp-5809	121	36	were	be	AUX
fnp-5809	121	37	identified	identify	VERB
fnp-5809	121	38	,	,	PUNCT
fnp-5809	121	39	partly	partly	ADV
fnp-5809	121	40	with	with	ADP
fnp-5809	121	41	a	a	DET
fnp-5809	121	42	heterozygous	heterozygous	ADJ
fnp-5809	121	43	germline	germline	NOUN
fnp-5809	121	44	mutation	mutation	NOUN
fnp-5809	121	45	(	(	PUNCT
fnp-5809	121	46	indicating	indicate	VERB
fnp-5809	121	47	an	an	DET
fnp-5809	121	48	underlying	underlie	VERB
fnp-5809	121	49	lynch	lynch	NOUN
fnp-5809	121	50	syndrome	syndrome	NOUN
fnp-5809	121	51	)	)	PUNCT
fnp-5809	121	52	in	in	ADP
fnp-5809	121	53	a	a	DET
fnp-5809	121	54	part	part	NOUN
fnp-5809	121	55	of	of	ADP
fnp-5809	121	56	the	the	DET
fnp-5809	121	57	glioblastoma	glioblastoma	NOUN
fnp-5809	121	58	patients	patient	NOUN
fnp-5809	122	1	[	[	X
fnp-5809	122	2	hadad	hadad	PROPN
fnp-5809	122	3	et	et	PROPN
fnp-5809	122	4	al	al	PROPN
fnp-5809	122	5	.	.	PROPN
fnp-5809	122	6	,	,	PUNCT
fnp-5809	122	7	2023	2023	NUM
fnp-5809	122	8	]	]	PUNCT
fnp-5809	122	9	.	.	PUNCT
fnp-5809	123	1	while	while	SCONJ
fnp-5809	123	2	overall	overall	ADJ
fnp-5809	123	3	mutation	mutation	NOUN
fnp-5809	123	4	rate	rate	NOUN
fnp-5809	123	5	was	be	AUX
fnp-5809	123	6	significantly	significantly	ADV
fnp-5809	123	7	increased	increase	VERB
fnp-5809	123	8	in	in	ADP
fnp-5809	123	9	this	this	DET
fnp-5809	123	10	tumor	tumor	NOUN
fnp-5809	123	11	group	group	NOUN
fnp-5809	123	12	,	,	PUNCT
fnp-5809	123	13	they	they	PRON
fnp-5809	123	14	showed	show	VERB
fnp-5809	123	15	lower	low	ADJ
fnp-5809	123	16	rates	rate	NOUN
fnp-5809	123	17	of	of	ADP
fnp-5809	123	18	classic	classic	ADJ
fnp-5809	123	19	genetic	genetic	ADJ
fnp-5809	123	20	glioblastoma	glioblastoma	NOUN
fnp-5809	123	21	alterations	alteration	NOUN
fnp-5809	123	22	such	such	ADJ
fnp-5809	123	23	as	as	ADP
fnp-5809	123	24	trisomy	trisomy	NOUN
fnp-5809	123	25	of	of	ADP
fnp-5809	123	26	chromosome	chromosome	NOUN
fnp-5809	123	27	7	7	NUM
fnp-5809	123	28	,	,	PUNCT
fnp-5809	123	29	monosomy	monosomy	NOUN
fnp-5809	123	30	of	of	ADP
fnp-5809	123	31	chromosome	chromosome	NOUN
fnp-5809	123	32	10	10	NUM
fnp-5809	123	33	,	,	PUNCT
fnp-5809	123	34	tert	tert	NOUN
fnp-5809	123	35	promoter	promoter	NOUN
fnp-5809	123	36	mutation	mutation	NOUN
fnp-5809	123	37	,	,	PUNCT
fnp-5809	123	38	egfr	egfr	ADJ
fnp-5809	123	39	amplification	amplification	NOUN
fnp-5809	123	40	or	or	CCONJ
fnp-5809	123	41	homozygous	homozygous	ADJ
fnp-5809	123	42	cdkn2a	cdkn2a	PROPN
fnp-5809	123	43	deletion	deletion	NOUN
fnp-5809	123	44	.	.	PUNCT
fnp-5809	124	1	in	in	ADP
fnp-5809	124	2	3	3	NUM
fnp-5809	124	3	out	out	ADP
fnp-5809	124	4	of	of	ADP
fnp-5809	124	5	those	those	DET
fnp-5809	124	6	9	9	NUM
fnp-5809	124	7	patients	patient	NOUN
fnp-5809	124	8	,	,	PUNCT
fnp-5809	124	9	additional	additional	ADJ
fnp-5809	124	10	mutations	mutation	NOUN
fnp-5809	124	11	in	in	ADP
fnp-5809	124	12	the	the	DET
fnp-5809	124	13	proofreading	proofreading	NOUN
fnp-5809	124	14	domain	domain	NOUN
fnp-5809	124	15	of	of	ADP
fnp-5809	124	16	the	the	DET
fnp-5809	124	17	dna	dna	PROPN
fnp-5809	124	18	polymerase	polymerase	NOUN
fnp-5809	124	19	pole	pole	NOUN
fnp-5809	124	20	were	be	AUX
fnp-5809	124	21	detected	detect	VERB
fnp-5809	124	22	being	be	AUX
fnp-5809	124	23	associated	associate	VERB
fnp-5809	124	24	with	with	ADP
fnp-5809	124	25	an	an	DET
fnp-5809	124	26	ultrahypermutational	ultrahypermutational	ADJ
fnp-5809	124	27	state	state	NOUN
fnp-5809	124	28	of	of	ADP
fnp-5809	124	29	more	more	ADJ
fnp-5809	124	30	than	than	ADP
fnp-5809	124	31	100	100	NUM
fnp-5809	124	32	mutations	mutation	NOUN
fnp-5809	124	33	per	per	ADP
fnp-5809	124	34	megabase	megabase	NOUN
fnp-5809	124	35	.	.	PUNCT
fnp-5809	125	1	of	of	ADP
fnp-5809	125	2	note	note	NOUN
fnp-5809	125	3	,	,	PUNCT
fnp-5809	125	4	the	the	DET
fnp-5809	125	5	mismatch	mismatch	ADJ
fnp-5809	125	6	repair	repair	NOUN
fnp-5809	125	7	deficient	deficient	ADJ
fnp-5809	125	8	(	(	PUNCT
fnp-5809	125	9	mrd	mrd	PROPN
fnp-5809	125	10	)	)	PUNCT
fnp-5809	125	11	glioblastomas	glioblastoma	NOUN
fnp-5809	125	12	presented	present	VERB
fnp-5809	125	13	as	as	ADP
fnp-5809	125	14	a	a	DET
fnp-5809	125	15	giant	giant	ADJ
fnp-5809	125	16	cell	cell	NOUN
fnp-5809	125	17	variant	variant	NOUN
fnp-5809	125	18	of	of	ADP
fnp-5809	125	19	glioblastoma	glioblastoma	NOUN
fnp-5809	125	20	and	and	CCONJ
fnp-5809	125	21	dna	dna	PROPN
fnp-5809	125	22	methylation	methylation	NOUN
fnp-5809	125	23	profile	profile	NOUN
fnp-5809	125	24	either	either	CCONJ
fnp-5809	125	25	matched	match	VERB
fnp-5809	125	26	with	with	ADP
fnp-5809	125	27	“	"	PUNCT
fnp-5809	125	28	diffuse	diffuse	VERB
fnp-5809	125	29	pediatric	pediatric	ADJ
fnp-5809	125	30	-	-	PUNCT
fnp-5809	125	31	type	type	NOUN
fnp-5809	125	32	hgg	hgg	NOUN
fnp-5809	125	33	,	,	PUNCT
fnp-5809	125	34	rtk1	rtk1	NOUN
fnp-5809	125	35	subtype	subtype	NOUN
fnp-5809	125	36	,	,	PUNCT
fnp-5809	125	37	subclass	subclass	VERB
fnp-5809	125	38	a	a	DET
fnp-5809	125	39	”	"	PUNCT
fnp-5809	125	40	,	,	PUNCT
fnp-5809	125	41	“	"	PUNCT
fnp-5809	125	42	adult	adult	NOUN
fnp-5809	125	43	-	-	PUNCT
fnp-5809	125	44	type	type	NOUN
fnp-5809	125	45	diffuse	diffuse	NOUN
fnp-5809	125	46	hgg	hgg	NOUN
fnp-5809	125	47	,	,	PUNCT
fnp-5809	125	48	idh	idh	NOUN
fnp-5809	125	49	-	-	PUNCT
fnp-5809	125	50	wt	wt	NOUN
fnp-5809	125	51	,	,	PUNCT
fnp-5809	125	52	subtype	subtype	NOUN
fnp-5809	125	53	e	e	NOUN
fnp-5809	125	54	”	"	PUNCT
fnp-5809	125	55	or	or	CCONJ
fnp-5809	125	56	did	do	AUX
fnp-5809	125	57	not	not	PART
fnp-5809	125	58	match	match	VERB
fnp-5809	125	59	at	at	ADV
fnp-5809	125	60	all	all	ADV
fnp-5809	125	61	.	.	PUNCT
fnp-5809	126	1	clinically	clinically	ADV
fnp-5809	126	2	,	,	PUNCT
fnp-5809	126	3	the	the	DET
fnp-5809	126	4	median	median	ADJ
fnp-5809	126	5	age	age	NOUN
fnp-5809	126	6	at	at	ADP
fnp-5809	126	7	tumor	tumor	NOUN
fnp-5809	126	8	occurrence	occurrence	NOUN
fnp-5809	126	9	was	be	AUX
fnp-5809	126	10	significantly	significantly	ADV
fnp-5809	126	11	lower	low	ADJ
fnp-5809	126	12	(	(	PUNCT
fnp-5809	126	13	50	50	NUM
fnp-5809	126	14	years	year	NOUN
fnp-5809	126	15	)	)	PUNCT
fnp-5809	126	16	in	in	ADP
fnp-5809	126	17	the	the	DET
fnp-5809	126	18	mrd	mrd	ADJ
fnp-5809	126	19	group	group	NOUN
fnp-5809	126	20	as	as	SCONJ
fnp-5809	126	21	compared	compare	VERB
fnp-5809	126	22	to	to	ADP
fnp-5809	126	23	non	non	ADJ
fnp-5809	126	24	-	-	ADJ
fnp-5809	126	25	mrd	mrd	ADJ
fnp-5809	126	26	glioblastoma	glioblastoma	NOUN
fnp-5809	126	27	patients	patient	NOUN
fnp-5809	126	28	(	(	PUNCT
fnp-5809	126	29	63	63	NUM
fnp-5809	126	30	years	year	NOUN
fnp-5809	126	31	)	)	PUNCT
fnp-5809	126	32	.	.	PUNCT
fnp-5809	127	1	in	in	ADP
fnp-5809	127	2	addition	addition	NOUN
fnp-5809	127	3	,	,	PUNCT
fnp-5809	127	4	median	median	ADJ
fnp-5809	127	5	overall	overall	ADJ
fnp-5809	127	6	survival	survival	NOUN
fnp-5809	127	7	was	be	AUX
fnp-5809	127	8	more	more	ADJ
fnp-5809	127	9	than	than	ADP
fnp-5809	127	10	twice	twice	ADV
fnp-5809	127	11	as	as	ADV
fnp-5809	127	12	long	long	ADJ
fnp-5809	127	13	(	(	PUNCT
fnp-5809	127	14	36.8	36.8	NUM
fnp-5809	127	15	months	month	NOUN
fnp-5809	127	16	)	)	PUNCT
fnp-5809	127	17	in	in	ADP
fnp-5809	127	18	mrd	mrd	ADJ
fnp-5809	127	19	glioblastoma	glioblastoma	NOUN
fnp-5809	127	20	as	as	SCONJ
fnp-5809	127	21	compared	compare	VERB
fnp-5809	127	22	to	to	ADP
fnp-5809	127	23	non	non	ADJ
fnp-5809	127	24	-	-	ADJ
fnp-5809	127	25	mrd	mrd	ADJ
fnp-5809	127	26	patients	patient	NOUN
fnp-5809	127	27	(	(	PUNCT
fnp-5809	127	28	15.5	15.5	NUM
fnp-5809	127	29	months	month	NOUN
fnp-5809	127	30	)	)	PUNCT
fnp-5809	127	31	.	.	PUNCT
fnp-5809	128	1	microscopically	microscopically	ADV
fnp-5809	128	2	,	,	PUNCT
fnp-5809	128	3	mrd	mrd	ADJ
fnp-5809	128	4	glioblastoma	glioblastoma	NOUN
fnp-5809	128	5	were	be	AUX
fnp-5809	128	6	associated	associate	VERB
fnp-5809	128	7	with	with	ADP
fnp-5809	128	8	significantly	significantly	ADV
fnp-5809	128	9	more	more	ADJ
fnp-5809	128	10	cd8	cd8	PROPN
fnp-5809	128	11	+	+	ADJ
fnp-5809	128	12	cytotoxic	cytotoxic	ADJ
fnp-5809	128	13	t	t	NOUN
fnp-5809	128	14	cells	cell	NOUN
fnp-5809	128	15	and	and	CCONJ
fnp-5809	128	16	microglia	microglia	ADJ
fnp-5809	128	17	cells	cell	NOUN
fnp-5809	128	18	indicating	indicate	VERB
fnp-5809	128	19	a	a	DET
fnp-5809	128	20	stronger	strong	ADJ
fnp-5809	128	21	immune	immune	ADJ
fnp-5809	128	22	activation	activation	NOUN
fnp-5809	128	23	in	in	ADP
fnp-5809	128	24	the	the	DET
fnp-5809	128	25	context	context	NOUN
fnp-5809	128	26	of	of	ADP
fnp-5809	128	27	a	a	DET
fnp-5809	128	28	hypermutational	hypermutational	ADJ
fnp-5809	128	29	state	state	NOUN
fnp-5809	128	30	.	.	PUNCT
fnp-5809	129	1	as	as	SCONJ
fnp-5809	129	2	smaller	small	ADJ
fnp-5809	129	3	studies	study	NOUN
fnp-5809	129	4	demonstrated	demonstrate	VERB
fnp-5809	129	5	that	that	SCONJ
fnp-5809	129	6	some	some	DET
fnp-5809	129	7	mrd	mrd	ADJ
fnp-5809	129	8	glioblastoma	glioblastoma	NOUN
fnp-5809	129	9	patients	patient	NOUN
fnp-5809	129	10	radiologically	radiologically	ADV
fnp-5809	129	11	and	and	CCONJ
fnp-5809	129	12	clinically	clinically	ADV
fnp-5809	129	13	profited	profit	VERB
fnp-5809	129	14	from	from	ADP
fnp-5809	129	15	immune	immune	ADJ
fnp-5809	129	16	checkpoint	checkpoint	NOUN
fnp-5809	129	17	inhibition	inhibition	NOUN
fnp-5809	129	18	treatment	treatment	NOUN
fnp-5809	129	19	,	,	PUNCT
fnp-5809	129	20	the	the	DET
fnp-5809	129	21	identification	identification	NOUN
fnp-5809	129	22	of	of	ADP
fnp-5809	129	23	such	such	ADJ
fnp-5809	129	24	patients	patient	NOUN
fnp-5809	129	25	(	(	PUNCT
fnp-5809	129	26	table	table	NOUN
fnp-5809	129	27	2	2	NUM
fnp-5809	129	28	)	)	PUNCT
fnp-5809	129	29	is	be	AUX
fnp-5809	129	30	important	important	ADJ
fnp-5809	130	1	[	[	X
fnp-5809	130	2	bouffet	bouffet	NOUN
fnp-5809	130	3	et	et	PROPN
fnp-5809	130	4	al	al	PROPN
fnp-5809	130	5	.	.	PROPN
fnp-5809	130	6	,	,	PUNCT
fnp-5809	130	7	2016	2016	NUM
fnp-5809	130	8	]	]	PUNCT
fnp-5809	130	9	.	.	PUNCT
fnp-5809	131	1	with	with	ADP
fnp-5809	131	2	this	this	PRON
fnp-5809	131	3	,	,	PUNCT
fnp-5809	131	4	a	a	DET
fnp-5809	131	5	better	well	ADV
fnp-5809	131	6	clinical	clinical	ADJ
fnp-5809	131	7	patient	patient	NOUN
fnp-5809	131	8	stratification	stratification	NOUN
fnp-5809	131	9	regarding	regard	VERB
fnp-5809	131	10	improved	improved	ADJ
fnp-5809	131	11	survival	survival	NOUN
fnp-5809	131	12	times	time	NOUN
fnp-5809	131	13	and	and	CCONJ
fnp-5809	131	14	suitability	suitability	NOUN
fnp-5809	131	15	for	for	ADP
fnp-5809	131	16	treatments	treatment	NOUN
fnp-5809	131	17	with	with	ADP
fnp-5809	131	18	immune	immune	ADJ
fnp-5809	131	19	checkpoint	checkpoint	NOUN
fnp-5809	131	20	inhibitors	inhibitor	NOUN
fnp-5809	131	21	is	be	AUX
fnp-5809	131	22	possible	possible	ADJ
fnp-5809	131	23	.	.	PUNCT
fnp-5809	132	1	table	table	NOUN
fnp-5809	132	2	2	2	NUM
fnp-5809	132	3	:	:	PUNCT
fnp-5809	132	4	clinical	clinical	ADJ
fnp-5809	132	5	and	and	CCONJ
fnp-5809	132	6	neuropathological	neuropathological	ADJ
fnp-5809	132	7	parameters	parameter	NOUN
fnp-5809	132	8	that	that	PRON
fnp-5809	132	9	should	should	AUX
fnp-5809	132	10	trigger	trigger	VERB
fnp-5809	132	11	mmr	mmr	PROPN
fnp-5809	132	12	and	and	CCONJ
fnp-5809	132	13	tmb	tmb	NOUN
fnp-5809	132	14	testing	testing	NOUN
fnp-5809	132	15	in	in	ADP
fnp-5809	132	16	patients	patient	NOUN
fnp-5809	132	17	with	with	ADP
fnp-5809	132	18	high	high	ADJ
fnp-5809	132	19	-	-	PUNCT
fnp-5809	132	20	grade	grade	NOUN
fnp-5809	132	21	gliomas	glioma	NOUN
fnp-5809	132	22	.	.	PUNCT
fnp-5809	133	1	7	7	X
fnp-5809	133	2	.	.	X
fnp-5809	133	3	ultra	ultra	ADJ
fnp-5809	133	4	-	-	ADJ
fnp-5809	133	5	fast	fast	ADJ
fnp-5809	133	6	,	,	PUNCT
fnp-5809	133	7	machine	machine	NOUN
fnp-5809	133	8	-	-	PUNCT
fnp-5809	133	9	learning	learning	NOUN
fnp-5809	133	10	based	base	VERB
fnp-5809	133	11	intraoperative	intraoperative	ADJ
fnp-5809	133	12	methylation	methylation	NOUN
fnp-5809	133	13	profiling	profiling	NOUN
fnp-5809	133	14	[	[	X
fnp-5809	133	15	vermeulen	vermeulen	PROPN
fnp-5809	133	16	et	et	PROPN
fnp-5809	133	17	al	al	PROPN
fnp-5809	133	18	.	.	PROPN
fnp-5809	133	19	,	,	PUNCT
fnp-5809	133	20	2023	2023	NUM
fnp-5809	133	21	]	]	PUNCT
fnp-5809	133	22	.	.	PUNCT
fnp-5809	134	1	methylation	methylation	NOUN
fnp-5809	134	2	profiling	profiling	NOUN
fnp-5809	134	3	considerably	considerably	ADV
fnp-5809	134	4	improved	improve	VERB
fnp-5809	134	5	the	the	DET
fnp-5809	134	6	unbiased	unbiased	ADJ
fnp-5809	134	7	and	and	CCONJ
fnp-5809	134	8	precise	precise	ADJ
fnp-5809	134	9	classification	classification	NOUN
fnp-5809	134	10	of	of	ADP
fnp-5809	134	11	brain	brain	NOUN
fnp-5809	134	12	tumors	tumor	NOUN
fnp-5809	134	13	and	and	CCONJ
fnp-5809	134	14	was	be	AUX
fnp-5809	134	15	rapidly	rapidly	ADV
fnp-5809	134	16	acknowledged	acknowledge	VERB
fnp-5809	134	17	as	as	ADP
fnp-5809	134	18	an	an	DET
fnp-5809	134	19	essential	essential	ADJ
fnp-5809	134	20	criterium	criterium	NOUN
fnp-5809	134	21	for	for	ADP
fnp-5809	134	22	diagnostics	diagnostic	NOUN
fnp-5809	134	23	of	of	ADP
fnp-5809	134	24	most	most	ADJ
fnp-5809	134	25	brain	brain	NOUN
fnp-5809	134	26	tumor	tumor	NOUN
fnp-5809	134	27	entities	entity	NOUN
fnp-5809	134	28	by	by	ADP
fnp-5809	134	29	the	the	PRON
fnp-5809	134	30	who	who	PRON
fnp-5809	134	31	guidelines	guideline	VERB
fnp-5809	134	32	[	[	X
fnp-5809	134	33	capper	capper	NOUN
fnp-5809	134	34	et	et	NOUN
fnp-5809	134	35	al	al	PROPN
fnp-5809	134	36	.	.	PROPN
fnp-5809	134	37	,	,	PUNCT
fnp-5809	134	38	2018	2018	NUM
fnp-5809	134	39	;	;	PUNCT
fnp-5809	134	40	who	who	PRON
fnp-5809	134	41	classification	classification	NOUN
fnp-5809	134	42	of	of	ADP
fnp-5809	134	43	brain	brain	NOUN
fnp-5809	134	44	tumors	tumor	NOUN
fnp-5809	134	45	,	,	PUNCT
fnp-5809	134	46	2021	2021	NUM
fnp-5809	134	47	]	]	PUNCT
fnp-5809	134	48	.	.	PUNCT
fnp-5809	135	1	most	most	ADJ
fnp-5809	135	2	institutions	institution	NOUN
fnp-5809	135	3	performing	perform	VERB
fnp-5809	135	4	methylation	methylation	NOUN
fnp-5809	135	5	profiling	profiling	NOUN
fnp-5809	135	6	still	still	ADV
fnp-5809	135	7	use	use	VERB
fnp-5809	135	8	an	an	DET
fnp-5809	135	9	array	array	NOUN
fnp-5809	135	10	-	-	PUNCT
fnp-5809	135	11	based	base	VERB
fnp-5809	135	12	approach	approach	NOUN
fnp-5809	135	13	for	for	ADP
fnp-5809	135	14	which	which	PRON
fnp-5809	135	15	the	the	DET
fnp-5809	135	16	entire	entire	ADJ
fnp-5809	135	17	laboratory	laboratory	NOUN
fnp-5809	135	18	process	process	NOUN
fnp-5809	135	19	before	before	SCONJ
fnp-5809	135	20	bioinformatic	bioinformatic	ADJ
fnp-5809	135	21	analyses	analysis	NOUN
fnp-5809	135	22	takes	take	VERB
fnp-5809	135	23	approximately	approximately	ADV
fnp-5809	135	24	one	one	NUM
fnp-5809	135	25	week	week	NOUN
fnp-5809	135	26	.	.	PUNCT
fnp-5809	136	1	however	however	ADV
fnp-5809	136	2	,	,	PUNCT
fnp-5809	136	3	for	for	ADP
fnp-5809	136	4	the	the	DET
fnp-5809	136	5	intraoperative	intraoperative	ADJ
fnp-5809	136	6	surgical	surgical	ADJ
fnp-5809	136	7	guidance	guidance	NOUN
fnp-5809	136	8	and	and	CCONJ
fnp-5809	136	9	potentially	potentially	ADV
fnp-5809	136	10	upcoming	upcoming	ADJ
fnp-5809	136	11	new	new	ADJ
fnp-5809	136	12	treatment	treatment	NOUN
fnp-5809	136	13	approaches	approach	NOUN
fnp-5809	136	14	with	with	ADP
fnp-5809	136	15	application	application	NOUN
fnp-5809	136	16	of	of	ADP
fnp-5809	136	17	substances	substance	NOUN
fnp-5809	136	18	or	or	CCONJ
fnp-5809	136	19	cells	cell	NOUN
fnp-5809	136	20	directly	directly	ADV
fnp-5809	136	21	in	in	ADP
fnp-5809	136	22	the	the	DET
fnp-5809	136	23	tumor	tumor	NOUN
fnp-5809	136	24	cavity	cavity	NOUN
fnp-5809	136	25	,	,	PUNCT
fnp-5809	136	26	it	it	PRON
fnp-5809	136	27	might	might	AUX
fnp-5809	136	28	be	be	AUX
fnp-5809	136	29	important	important	ADJ
fnp-5809	136	30	to	to	PART
fnp-5809	136	31	have	have	VERB
fnp-5809	136	32	a	a	DET
fnp-5809	136	33	precise	precise	ADJ
fnp-5809	136	34	,	,	PUNCT
fnp-5809	136	35	rapid	rapid	ADJ
fnp-5809	136	36	on	on	ADP
fnp-5809	136	37	-	-	PUNCT
fnp-5809	136	38	site	site	NOUN
fnp-5809	136	39	diagnosis	diagnosis	NOUN
fnp-5809	136	40	.	.	PUNCT
fnp-5809	137	1	as	as	SCONJ
fnp-5809	137	2	brain	brain	NOUN
fnp-5809	137	3	tumors	tumor	NOUN
fnp-5809	137	4	are	be	AUX
fnp-5809	137	5	more	more	ADV
fnp-5809	137	6	and	and	CCONJ
fnp-5809	137	7	more	more	ADV
fnp-5809	137	8	stratified	stratified	ADJ
fnp-5809	137	9	according	accord	VERB
fnp-5809	137	10	to	to	ADP
fnp-5809	137	11	molecular	molecular	ADJ
fnp-5809	137	12	classes	class	NOUN
fnp-5809	137	13	,	,	PUNCT
fnp-5809	137	14	an	an	DET
fnp-5809	137	15	intraoperative	intraoperative	ADJ
fnp-5809	137	16	histological	histological	ADJ
fnp-5809	137	17	assessment	assessment	NOUN
fnp-5809	137	18	for	for	ADP
fnp-5809	137	19	primary	primary	ADJ
fnp-5809	137	20	cerebral	cerebral	ADJ
fnp-5809	137	21	neoplasms	neoplasm	NOUN
fnp-5809	137	22	is	be	AUX
fnp-5809	137	23	of	of	ADP
fnp-5809	137	24	limited	limited	ADJ
fnp-5809	137	25	interest	interest	NOUN
fnp-5809	137	26	in	in	ADP
fnp-5809	137	27	many	many	ADJ
fnp-5809	137	28	such	such	ADJ
fnp-5809	137	29	cases	case	NOUN
fnp-5809	137	30	.	.	PUNCT
fnp-5809	138	1	to	to	PART
fnp-5809	138	2	overcome	overcome	VERB
fnp-5809	138	3	those	those	DET
fnp-5809	138	4	obstacles	obstacle	NOUN
fnp-5809	138	5	,	,	PUNCT
fnp-5809	138	6	a	a	DET
fnp-5809	138	7	fast	fast	ADJ
fnp-5809	138	8	genomic	genomic	NOUN
fnp-5809	138	9	and	and	CCONJ
fnp-5809	138	10	epigenomic	epigenomic	ADJ
fnp-5809	138	11	assessment	assessment	NOUN
fnp-5809	138	12	using	use	VERB
fnp-5809	138	13	nanopore	nanopore	ADV
fnp-5809	138	14	sequencing	sequencing	NOUN
fnp-5809	138	15	had	have	AUX
fnp-5809	138	16	been	be	AUX
fnp-5809	138	17	previously	previously	ADV
fnp-5809	138	18	developed	develop	VERB
fnp-5809	139	1	[	[	PUNCT
fnp-5809	139	2	euskirchen	euskirchen	ADV
fnp-5809	139	3	et	et	PROPN
fnp-5809	139	4	al	al	PROPN
fnp-5809	139	5	.	.	PROPN
fnp-5809	139	6	,	,	PUNCT
fnp-5809	139	7	2017	2017	NUM
fnp-5809	139	8	]	]	PUNCT
fnp-5809	139	9	.	.	PUNCT
fnp-5809	140	1	the	the	DET
fnp-5809	140	2	authors	author	NOUN
fnp-5809	140	3	of	of	ADP
fnp-5809	140	4	the	the	DET
fnp-5809	140	5	current	current	ADJ
fnp-5809	140	6	study	study	NOUN
fnp-5809	140	7	applied	apply	VERB
fnp-5809	140	8	nanopore	nanopore	ADV
fnp-5809	140	9	sequencing	sequencing	NOUN
fnp-5809	140	10	in	in	ADP
fnp-5809	140	11	combination	combination	NOUN
fnp-5809	140	12	with	with	ADP
fnp-5809	140	13	a	a	DET
fnp-5809	140	14	neural	neural	ADJ
fnp-5809	140	15	network	network	NOUN
fnp-5809	140	16	analysis	analysis	NOUN
fnp-5809	140	17	(	(	PUNCT
fnp-5809	140	18	named	name	VERB
fnp-5809	140	19	“	"	PUNCT
fnp-5809	140	20	sturgeon	sturgeon	NOUN
fnp-5809	140	21	”	"	PUNCT
fnp-5809	140	22	)	)	PUNCT
fnp-5809	140	23	to	to	PART
fnp-5809	140	24	molecularly	molecularly	ADV
fnp-5809	140	25	classify	classify	VERB
fnp-5809	140	26	cns	cns	NOUN
fnp-5809	140	27	tumors	tumor	NOUN
fnp-5809	140	28	intraoperatively	intraoperatively	ADV
fnp-5809	141	1	[	[	X
fnp-5809	141	2	vermeulen	vermeulen	X
fnp-5809	141	3	et	et	PROPN
fnp-5809	141	4	al	al	PROPN
fnp-5809	141	5	.	.	PROPN
fnp-5809	141	6	,	,	PUNCT
fnp-5809	141	7	2023	2023	NUM
fnp-5809	141	8	]	]	PUNCT
fnp-5809	141	9	.	.	PUNCT
fnp-5809	142	1	in	in	ADP
fnp-5809	142	2	45	45	NUM
fnp-5809	142	3	out	out	ADP
fnp-5809	142	4	of	of	ADP
fnp-5809	142	5	50	50	NUM
fnp-5809	142	6	samples	sample	NOUN
fnp-5809	142	7	,	,	PUNCT
fnp-5809	142	8	an	an	DET
fnp-5809	142	9	accurate	accurate	ADJ
fnp-5809	142	10	diagnosis	diagnosis	NOUN
fnp-5809	142	11	was	be	AUX
fnp-5809	142	12	already	already	ADV
fnp-5809	142	13	obtained	obtain	VERB
fnp-5809	142	14	40	40	NUM
fnp-5809	142	15	min	min	NOUN
fnp-5809	142	16	after	after	ADP
fnp-5809	142	17	initiation	initiation	NOUN
fnp-5809	142	18	of	of	ADP
fnp-5809	142	19	the	the	DET
fnp-5809	142	20	sequencing	sequence	VERB
fnp-5809	142	21	procedure	procedure	NOUN
fnp-5809	142	22	in	in	ADP
fnp-5809	142	23	a	a	DET
fnp-5809	142	24	retrospective	retrospective	ADJ
fnp-5809	142	25	cohort	cohort	NOUN
fnp-5809	142	26	.	.	PUNCT
fnp-5809	143	1	after	after	ADP
fnp-5809	143	2	this	this	DET
fnp-5809	143	3	highly	highly	ADV
fnp-5809	143	4	promising	promising	ADJ
fnp-5809	143	5	proof	proof	NOUN
fnp-5809	143	6	of	of	ADP
fnp-5809	143	7	concept	concept	NOUN
fnp-5809	143	8	results	result	NOUN
fnp-5809	143	9	,	,	PUNCT
fnp-5809	143	10	the	the	DET
fnp-5809	143	11	authors	author	NOUN
fnp-5809	143	12	were	be	AUX
fnp-5809	143	13	able	able	ADJ
fnp-5809	143	14	to	to	PART
fnp-5809	143	15	achieve	achieve	VERB
fnp-5809	143	16	intraoperative	intraoperative	ADJ
fnp-5809	143	17	molecular	molecular	ADJ
fnp-5809	143	18	diagnoses	diagnosis	NOUN
fnp-5809	143	19	within	within	ADP
fnp-5809	143	20	a	a	DET
fnp-5809	143	21	turnaround	turnaround	NOUN
fnp-5809	143	22	time	time	NOUN
fnp-5809	143	23	of	of	ADP
fnp-5809	143	24	90	90	NUM
fnp-5809	143	25	min	min	NOUN
fnp-5809	143	26	.	.	PUNCT
fnp-5809	143	27	a	a	DET
fnp-5809	143	28	major	major	ADJ
fnp-5809	143	29	advantage	advantage	NOUN
fnp-5809	143	30	of	of	ADP
fnp-5809	143	31	the	the	DET
fnp-5809	143	32	sturgeon	sturgeon	NOUN
fnp-5809	143	33	model	model	NOUN
fnp-5809	143	34	is	be	AUX
fnp-5809	143	35	that	that	SCONJ
fnp-5809	143	36	it	it	PRON
fnp-5809	143	37	can	can	AUX
fnp-5809	143	38	be	be	AUX
fnp-5809	143	39	universally	universally	ADV
fnp-5809	143	40	used	use	VERB
fnp-5809	143	41	without	without	ADP
fnp-5809	143	42	retraining	retrain	VERB
fnp-5809	143	43	(	(	PUNCT
fnp-5809	143	44	see	see	VERB
fnp-5809	143	45	https://github.com/marcpaga/sturgeon	https://github.com/marcpaga/sturgeon	NOUN
fnp-5809	143	46	)	)	PUNCT
fnp-5809	143	47	on	on	ADP
fnp-5809	143	48	several	several	ADJ
fnp-5809	143	49	different	different	ADJ
fnp-5809	143	50	flow	flow	NOUN
fnp-5809	143	51	cell	cell	NOUN
fnp-5809	143	52	types	type	NOUN
fnp-5809	143	53	(	(	PUNCT
fnp-5809	143	54	e.g.	e.g.	ADV
fnp-5809	143	55	minion	minion	NOUN
fnp-5809	143	56	or	or	CCONJ
fnp-5809	143	57	promethion	promethion	NOUN
fnp-5809	143	58	using	use	VERB
fnp-5809	143	59	r9	r9	NOUN
fnp-5809	143	60	and	and	CCONJ
fnp-5809	143	61	r10	r10	NUM
fnp-5809	143	62	chemistry	chemistry	NOUN
fnp-5809	143	63	)	)	PUNCT
fnp-5809	143	64	.	.	PUNCT
fnp-5809	144	1	however	however	ADV
fnp-5809	144	2	,	,	PUNCT
fnp-5809	144	3	the	the	DET
fnp-5809	144	4	method	method	NOUN
fnp-5809	144	5	is	be	AUX
fnp-5809	144	6	still	still	ADV
fnp-5809	144	7	strongly	strongly	ADV
fnp-5809	144	8	dependent	dependent	ADJ
fnp-5809	144	9	on	on	ADP
fnp-5809	144	10	the	the	DET
fnp-5809	144	11	tumor	tumor	NOUN
fnp-5809	144	12	cell	cell	NOUN
fnp-5809	144	13	content	content	NOUN
fnp-5809	144	14	.	.	PUNCT
fnp-5809	145	1	therefore	therefore	ADV
fnp-5809	145	2	,	,	PUNCT
fnp-5809	145	3	a	a	DET
fnp-5809	145	4	concomitant	concomitant	NOUN
fnp-5809	145	5	mirroring	mirror	VERB
fnp-5809	145	6	histological	histological	ADJ
fnp-5809	145	7	assessment	assessment	NOUN
fnp-5809	145	8	of	of	ADP
fnp-5809	145	9	the	the	DET
fnp-5809	145	10	tissue	tissue	NOUN
fnp-5809	145	11	assessed	assess	VERB
fnp-5809	145	12	by	by	ADP
fnp-5809	145	13	the	the	DET
fnp-5809	145	14	sturgeon	sturgeon	NOUN
fnp-5809	145	15	model	model	NOUN
fnp-5809	145	16	could	could	AUX
fnp-5809	145	17	be	be	AUX
fnp-5809	145	18	beneficial	beneficial	ADJ
fnp-5809	145	19	.	.	PUNCT
fnp-5809	146	1	8	8	X
fnp-5809	146	2	.	.	X
fnp-5809	146	3	multiomics	multiomics	PROPN
fnp-5809	146	4	neuropathology	neuropathology	NOUN
fnp-5809	146	5	improving	improve	VERB
fnp-5809	146	6	diagnostic	diagnostic	ADJ
fnp-5809	146	7	precision	precision	NOUN
fnp-5809	146	8	,	,	PUNCT
fnp-5809	146	9	targeted	target	VERB
fnp-5809	146	10	therapy	therapy	NOUN
fnp-5809	146	11	and	and	CCONJ
fnp-5809	146	12	detection	detection	NOUN
fnp-5809	146	13	of	of	ADP
fnp-5809	146	14	cancer	cancer	NOUN
fnp-5809	146	15	predisposition	predisposition	NOUN
fnp-5809	146	16	syndromes	syndrome	NOUN
fnp-5809	146	17	in	in	ADP
fnp-5809	146	18	pediatric	pediatric	ADJ
fnp-5809	146	19	neurooncology	neurooncology	NOUN
fnp-5809	147	1	[	[	X
fnp-5809	147	2	sturm	sturm	PROPN
fnp-5809	147	3	et	et	PROPN
fnp-5809	147	4	al	al	PROPN
fnp-5809	147	5	.	.	PROPN
fnp-5809	147	6	,	,	PUNCT
fnp-5809	147	7	2023	2023	NUM
fnp-5809	147	8	]	]	PUNCT
fnp-5809	147	9	.	.	PUNCT
fnp-5809	148	1	over	over	ADP
fnp-5809	148	2	the	the	DET
fnp-5809	148	3	past	past	ADJ
fnp-5809	148	4	decade	decade	NOUN
fnp-5809	148	5	,	,	PUNCT
fnp-5809	148	6	diagnostic	diagnostic	ADJ
fnp-5809	148	7	improvement	improvement	NOUN
fnp-5809	148	8	in	in	ADP
fnp-5809	148	9	neuropathology	neuropathology	NOUN
fnp-5809	148	10	was	be	AUX
fnp-5809	148	11	strongly	strongly	ADV
fnp-5809	148	12	linked	link	VERB
fnp-5809	148	13	to	to	PART
fnp-5809	148	14	constantly	constantly	ADV
fnp-5809	148	15	improved	improve	VERB
fnp-5809	148	16	methylome	methylome	ADJ
fnp-5809	148	17	profiling	profiling	NOUN
fnp-5809	149	1	[	[	X
fnp-5809	149	2	https://	https://	PROPN
fnp-5809	149	3	www.molecularneuropathology.org/mnp	www.molecularneuropathology.org/mnp	PROPN
fnp-5809	149	4	based	base	VERB
fnp-5809	149	5	on	on	ADP
fnp-5809	149	6	capper	capper	NOUN
fnp-5809	149	7	et	et	PROPN
fnp-5809	149	8	al	al	PROPN
fnp-5809	149	9	.	.	PROPN
fnp-5809	149	10	2018	2018	NUM
fnp-5809	149	11	]	]	PUNCT
fnp-5809	149	12	.	.	PUNCT
fnp-5809	150	1	however	however	ADV
fnp-5809	150	2	,	,	PUNCT
fnp-5809	150	3	this	this	DET
fnp-5809	150	4	approach	approach	NOUN
fnp-5809	150	5	has	have	AUX
fnp-5809	150	6	not	not	PART
fnp-5809	150	7	yet	yet	ADV
fnp-5809	150	8	contributed	contribute	VERB
fnp-5809	150	9	significantly	significantly	ADV
fnp-5809	150	10	to	to	ADP
fnp-5809	150	11	improved	improve	VERB
fnp-5809	150	12	treatment	treatment	NOUN
fnp-5809	150	13	approaches	approach	NOUN
fnp-5809	150	14	,	,	PUNCT
fnp-5809	150	15	partially	partially	ADV
fnp-5809	150	16	due	due	ADP
fnp-5809	150	17	to	to	ADP
fnp-5809	150	18	a	a	DET
fnp-5809	150	19	lack	lack	NOUN
fnp-5809	150	20	of	of	ADP
fnp-5809	150	21	related	related	ADJ
fnp-5809	150	22	prognostic	prognostic	ADJ
fnp-5809	150	23	data	datum	NOUN
fnp-5809	150	24	or	or	CCONJ
fnp-5809	150	25	information	information	NOUN
fnp-5809	150	26	about	about	ADP
fnp-5809	150	27	underlying	underlie	VERB
fnp-5809	150	28	genetic	genetic	ADJ
fnp-5809	150	29	predisposition	predisposition	NOUN
fnp-5809	150	30	for	for	ADP
fnp-5809	150	31	tumor	tumor	NOUN
fnp-5809	150	32	development	development	NOUN
fnp-5809	150	33	that	that	PRON
fnp-5809	150	34	might	might	AUX
fnp-5809	150	35	be	be	AUX
fnp-5809	150	36	additionally	additionally	ADV
fnp-5809	150	37	important	important	ADJ
fnp-5809	150	38	for	for	ADP
fnp-5809	150	39	further	further	ADJ
fnp-5809	150	40	clinical	clinical	ADJ
fnp-5809	150	41	follow	follow	NOUN
fnp-5809	150	42	-	-	PUNCT
fnp-5809	150	43	up	up	NOUN
fnp-5809	150	44	[	[	X
fnp-5809	150	45	farouk	farouk	NOUN
fnp-5809	150	46	et	et	PROPN
fnp-5809	150	47	al	al	PROPN
fnp-5809	150	48	.	.	PROPN
fnp-5809	150	49	,	,	PUNCT
fnp-5809	150	50	2021	2021	NUM
fnp-5809	150	51	]	]	PUNCT
fnp-5809	150	52	.	.	PUNCT
fnp-5809	151	1	in	in	ADP
fnp-5809	151	2	their	their	PRON
fnp-5809	151	3	study	study	NOUN
fnp-5809	151	4	,	,	PUNCT
fnp-5809	151	5	sturm	sturm	PROPN
fnp-5809	151	6	et	et	PROPN
fnp-5809	151	7	al	al	PROPN
fnp-5809	151	8	.	.	PROPN
fnp-5809	151	9	combined	combined	ADJ
fnp-5809	151	10	methylation	methylation	NOUN
fnp-5809	151	11	profiling	profiling	NOUN
fnp-5809	151	12	with	with	ADP
fnp-5809	151	13	targeted	target	VERB
fnp-5809	151	14	panel	panel	NOUN
fnp-5809	151	15	sequencing	sequence	VERB
fnp-5809	151	16	in	in	ADP
fnp-5809	151	17	a	a	DET
fnp-5809	151	18	cohort	cohort	NOUN
fnp-5809	151	19	of	of	ADP
fnp-5809	151	20	more	more	ADJ
fnp-5809	151	21	than	than	ADP
fnp-5809	151	22	1,200	1,200	NUM
fnp-5809	151	23	newly	newly	ADV
fnp-5809	151	24	diagnosed	diagnose	VERB
fnp-5809	151	25	pediatric	pediatric	ADJ
fnp-5809	151	26	brain	brain	NOUN
fnp-5809	151	27	tumors	tumor	NOUN
fnp-5809	151	28	[	[	X
fnp-5809	151	29	sturm	sturm	X
fnp-5809	151	30	et	et	PROPN
fnp-5809	151	31	al	al	PROPN
fnp-5809	151	32	.	.	PROPN
fnp-5809	151	33	,	,	PUNCT
fnp-5809	151	34	2023	2023	NUM
fnp-5809	151	35	]	]	PUNCT
fnp-5809	151	36	.	.	PUNCT
fnp-5809	152	1	with	with	ADP
fnp-5809	152	2	this	this	DET
fnp-5809	152	3	approach	approach	NOUN
fnp-5809	152	4	,	,	PUNCT
fnp-5809	152	5	they	they	PRON
fnp-5809	152	6	were	be	AUX
fnp-5809	152	7	able	able	ADJ
fnp-5809	152	8	to	to	PART
fnp-5809	152	9	achieve	achieve	VERB
fnp-5809	152	10	a	a	DET
fnp-5809	152	11	refined	refined	ADJ
fnp-5809	152	12	diagnosis	diagnosis	NOUN
fnp-5809	152	13	in	in	ADP
fnp-5809	152	14	almost	almost	ADV
fnp-5809	152	15	every	every	PRON
fnp-5809	152	16	second	second	ADJ
fnp-5809	152	17	case	case	NOUN
fnp-5809	152	18	as	as	ADP
fnp-5809	152	19	compared	compare	VERB
fnp-5809	152	20	to	to	ADP
fnp-5809	152	21	current	current	VERB
fnp-5809	152	22	who	who	PRON
fnp-5809	152	23	classification	classification	VERB
fnp-5809	152	24	alone	alone	ADV
fnp-5809	152	25	.	.	PUNCT
fnp-5809	153	1	moreover	moreover	ADV
fnp-5809	153	2	,	,	PUNCT
fnp-5809	153	3	in	in	ADP
fnp-5809	153	4	almost	almost	ADV
fnp-5809	153	5	every	every	PRON
fnp-5809	153	6	second	second	ADJ
fnp-5809	153	7	case	case	NOUN
fnp-5809	153	8	,	,	PUNCT
fnp-5809	153	9	a	a	DET
fnp-5809	153	10	potential	potential	ADJ
fnp-5809	153	11	therapeutically	therapeutically	ADV
fnp-5809	153	12	relevant	relevant	ADJ
fnp-5809	153	13	alteration	alteration	NOUN
fnp-5809	153	14	was	be	AUX
fnp-5809	153	15	detected	detect	VERB
fnp-5809	153	16	and	and	CCONJ
fnp-5809	153	17	15	15	NUM
fnp-5809	153	18	 	 	SPACE
fnp-5809	153	19	%	%	NOUN
fnp-5809	153	20	of	of	ADP
fnp-5809	153	21	all	all	DET
fnp-5809	153	22	tumors	tumor	NOUN
fnp-5809	153	23	revealed	reveal	VERB
fnp-5809	153	24	a	a	DET
fnp-5809	153	25	directly	directly	ADV
fnp-5809	153	26	druggable	druggable	ADJ
fnp-5809	153	27	genetic	genetic	ADJ
fnp-5809	153	28	alteration	alteration	NOUN
fnp-5809	153	29	with	with	ADP
fnp-5809	153	30	braf	braf	NOUN
fnp-5809	153	31	-	-	PUNCT
fnp-5809	153	32	v600e	v600e	VERB
fnp-5809	153	33	being	be	AUX
fnp-5809	153	34	the	the	DET
fnp-5809	153	35	most	most	ADV
fnp-5809	153	36	frequent	frequent	ADJ
fnp-5809	153	37	(	(	PUNCT
fnp-5809	153	38	7.4	7.4	NUM
fnp-5809	153	39	 	 	SPACE
fnp-5809	153	40	%	%	NOUN
fnp-5809	153	41	)	)	PUNCT
fnp-5809	153	42	,	,	PUNCT
fnp-5809	153	43	followed	follow	VERB
fnp-5809	153	44	by	by	ADP
fnp-5809	153	45	fgfr1/3	fgfr1/3	NOUN
fnp-5809	153	46	(	(	PUNCT
fnp-5809	153	47	4.0	4.0	NUM
fnp-5809	153	48	 	 	SPACE
fnp-5809	153	49	%	%	NOUN
fnp-5809	153	50	)	)	PUNCT
fnp-5809	153	51	,	,	PUNCT
fnp-5809	153	52	alk	alk	VERB
fnp-5809	153	53	(	(	PUNCT
fnp-5809	153	54	0.8	0.8	NUM
fnp-5809	153	55	 	 	SPACE
fnp-5809	153	56	%	%	NOUN
fnp-5809	153	57	)	)	PUNCT
fnp-5809	153	58	,	,	PUNCT
fnp-5809	153	59	ntrk2/3	ntrk2/3	PROPN
fnp-5809	153	60	(	(	PUNCT
fnp-5809	153	61	0.4	0.4	NUM
fnp-5809	153	62	 	 	SPACE
fnp-5809	153	63	%	%	NOUN
fnp-5809	153	64	)	)	PUNCT
fnp-5809	153	65	,	,	PUNCT
fnp-5809	153	66	met	meet	VERB
fnp-5809	153	67	(	(	PUNCT
fnp-5809	153	68	0.1	0.1	NUM
fnp-5809	153	69	 	 	SPACE
fnp-5809	153	70	%	%	NOUN
fnp-5809	153	71	)	)	PUNCT
fnp-5809	153	72	and	and	CCONJ
fnp-5809	153	73	ret	ret	NOUN
fnp-5809	153	74	(	(	PUNCT
fnp-5809	153	75	0.1	0.1	NUM
fnp-5809	153	76	 	 	SPACE
fnp-5809	153	77	%	%	NOUN
fnp-5809	153	78	)	)	PUNCT
fnp-5809	153	79	.	.	PUNCT
fnp-5809	154	1	for	for	ADP
fnp-5809	154	2	10	10	NUM
fnp-5809	154	3	 	 	SPACE
fnp-5809	154	4	%	%	NOUN
fnp-5809	154	5	of	of	ADP
fnp-5809	154	6	all	all	DET
fnp-5809	154	7	cases	case	NOUN
fnp-5809	154	8	an	an	DET
fnp-5809	154	9	underlying	underlie	VERB
fnp-5809	154	10	cancer	cancer	NOUN
fnp-5809	154	11	predisposition	predisposition	NOUN
fnp-5809	154	12	syndrome	syndrome	NOUN
fnp-5809	154	13	was	be	AUX
fnp-5809	154	14	found	find	VERB
fnp-5809	154	15	,	,	PUNCT
fnp-5809	154	16	amongst	amongst	ADP
fnp-5809	154	17	those	those	PRON
fnp-5809	154	18	,	,	PUNCT
fnp-5809	154	19	most	most	ADV
fnp-5809	154	20	frequently	frequently	ADV
fnp-5809	154	21	neurofibromatosis	neurofibromatosis	NOUN
fnp-5809	154	22	type	type	NOUN
fnp-5809	154	23	1	1	NUM
fnp-5809	154	24	(	(	PUNCT
fnp-5809	154	25	1.5	1.5	NUM
fnp-5809	154	26	 	 	SPACE
fnp-5809	154	27	%	%	NOUN
fnp-5809	154	28	)	)	PUNCT
fnp-5809	154	29	,	,	PUNCT
fnp-5809	154	30	followed	follow	VERB
fnp-5809	154	31	by	by	ADP
fnp-5809	154	32	tp53	tp53	PROPN
fnp-5809	154	33	-	-	PUNCT
fnp-5809	154	34	related	relate	VERB
fnp-5809	154	35	li	li	NOUN
fnp-5809	154	36	-	-	ADJ
fnp-5809	154	37	fraumeni	fraumeni	ADJ
fnp-5809	154	38	syndrome	syndrome	NOUN
fnp-5809	154	39	(	(	PUNCT
fnp-5809	154	40	1.2	1.2	NUM
fnp-5809	154	41	 	 	SPACE
fnp-5809	154	42	%	%	NOUN
fnp-5809	154	43	)	)	PUNCT
fnp-5809	154	44	,	,	PUNCT
fnp-5809	154	45	constitutional	constitutional	ADJ
fnp-5809	154	46	mismatch	mismatch	NOUN
fnp-5809	154	47	repair	repair	NOUN
fnp-5809	154	48	gene	gene	NOUN
fnp-5809	154	49	deficiency	deficiency	NOUN
fnp-5809	154	50	or	or	CCONJ
fnp-5809	154	51	lynch	lynch	PROPN
fnp-5809	154	52	syndrome	syndrome	PROPN
fnp-5809	154	53	including	include	VERB
fnp-5809	154	54	mlh1	mlh1	PROPN
fnp-5809	154	55	,	,	PUNCT
fnp-5809	154	56	msh2	msh2	NOUN
fnp-5809	154	57	and	and	CCONJ
fnp-5809	154	58	msh6	msh6	NOUN
fnp-5809	154	59	genes	gene	NOUN
fnp-5809	154	60	(	(	PUNCT
fnp-5809	154	61	1.1	1.1	NUM
fnp-5809	154	62	 	 	SPACE
fnp-5809	154	63	%	%	NOUN
fnp-5809	154	64	)	)	PUNCT
fnp-5809	154	65	,	,	PUNCT
fnp-5809	154	66	ataxia	ataxia	NOUN
fnp-5809	154	67	-	-	PUNCT
fnp-5809	154	68	telangiectasia	telangiectasia	NOUN
fnp-5809	154	69	and	and	CCONJ
fnp-5809	154	70	atm	atm	VERB
fnp-5809	154	71	heterozygous	heterozygous	ADJ
fnp-5809	154	72	carriers	carrier	NOUN
fnp-5809	154	73	(	(	PUNCT
fnp-5809	154	74	0.9	0.9	NUM
fnp-5809	154	75	 	 	SPACE
fnp-5809	154	76	%	%	NOUN
fnp-5809	154	77	)	)	PUNCT
fnp-5809	154	78	,	,	PUNCT
fnp-5809	154	79	neurofibromatosis	neurofibromatosis	NOUN
fnp-5809	154	80	type	type	NOUN
fnp-5809	154	81	2	2	NUM
fnp-5809	154	82	(	(	PUNCT
fnp-5809	154	83	0.8	0.8	NUM
fnp-5809	154	84	 	 	SPACE
fnp-5809	154	85	%	%	NOUN
fnp-5809	154	86	)	)	PUNCT
fnp-5809	154	87	,	,	PUNCT
fnp-5809	154	88	dicer	dicer	NOUN
fnp-5809	154	89	syndrome	syndrome	NOUN
fnp-5809	154	90	(	(	PUNCT
fnp-5809	154	91	0.6	0.6	NUM
fnp-5809	154	92	 	 	SPACE
fnp-5809	154	93	%	%	NOUN
fnp-5809	154	94	)	)	PUNCT
fnp-5809	154	95	and	and	CCONJ
fnp-5809	154	96	rhabdoid	rhabdoid	VERB
fnp-5809	154	97	tumor	tumor	NOUN
fnp-5809	154	98	predisposition	predisposition	NOUN
fnp-5809	154	99	syndrome	syndrome	NOUN
fnp-5809	154	100	1	1	NUM
fnp-5809	154	101	related	relate	VERB
fnp-5809	154	102	to	to	ADP
fnp-5809	154	103	smarcb1	smarcb1	PROPN
fnp-5809	154	104	(	(	PUNCT
fnp-5809	154	105	0.4	0.4	NUM
fnp-5809	154	106	 	 	SPACE
fnp-5809	154	107	%	%	NOUN
fnp-5809	154	108	)	)	PUNCT
fnp-5809	154	109	were	be	AUX
fnp-5809	154	110	observed	observe	VERB
fnp-5809	154	111	.	.	PUNCT
fnp-5809	155	1	compared	compare	VERB
fnp-5809	155	2	to	to	ADP
fnp-5809	155	3	the	the	DET
fnp-5809	155	4	initial	initial	ADJ
fnp-5809	155	5	cohort	cohort	NOUN
fnp-5809	155	6	[	[	X
fnp-5809	155	7	capper	capper	NOUN
fnp-5809	155	8	et	et	NOUN
fnp-5809	155	9	al	al	PROPN
fnp-5809	155	10	.	.	PROPN
fnp-5809	155	11	,	,	PUNCT
fnp-5809	155	12	2018	2018	NUM
fnp-5809	155	13	]	]	PUNCT
fnp-5809	155	14	,	,	PUNCT
fnp-5809	155	15	3	3	NUM
fnp-5809	155	16	 	 	SPACE
fnp-5809	155	17	%	%	NOUN
fnp-5809	155	18	of	of	ADP
fnp-5809	155	19	pediatric	pediatric	ADJ
fnp-5809	155	20	neurooncological	neurooncological	ADJ
fnp-5809	155	21	cases	case	NOUN
fnp-5809	155	22	in	in	ADP
fnp-5809	155	23	the	the	DET
fnp-5809	155	24	present	present	ADJ
fnp-5809	155	25	study	study	NOUN
fnp-5809	155	26	belong	belong	VERB
fnp-5809	155	27	to	to	ADP
fnp-5809	155	28	potentially	potentially	ADV
fnp-5809	155	29	new	new	ADJ
fnp-5809	155	30	tumor	tumor	NOUN
fnp-5809	155	31	classes	class	NOUN
fnp-5809	155	32	.	.	PUNCT
fnp-5809	156	1	of	of	ADP
fnp-5809	156	2	note	note	NOUN
fnp-5809	156	3	,	,	PUNCT
fnp-5809	156	4	in	in	ADP
fnp-5809	156	5	up	up	ADP
fnp-5809	156	6	to	to	PART
fnp-5809	156	7	one	one	NUM
fnp-5809	156	8	third	third	NOUN
fnp-5809	156	9	of	of	ADP
fnp-5809	156	10	this	this	DET
fnp-5809	156	11	pediatric	pediatric	ADJ
fnp-5809	156	12	patient	patient	NOUN
fnp-5809	156	13	cohort	cohort	NOUN
fnp-5809	156	14	,	,	PUNCT
fnp-5809	156	15	discordant	discordant	ADJ
fnp-5809	156	16	results	result	NOUN
fnp-5809	156	17	were	be	AUX
fnp-5809	156	18	obtained	obtain	VERB
fnp-5809	156	19	when	when	SCONJ
fnp-5809	156	20	comparing	compare	VERB
fnp-5809	156	21	standard	standard	ADJ
fnp-5809	156	22	whoand	whoand	NOUN
fnp-5809	156	23	methylation	methylation	NOUN
fnp-5809	156	24	-	-	PUNCT
fnp-5809	156	25	based	base	VERB
fnp-5809	156	26	analyses	analysis	NOUN
fnp-5809	156	27	,	,	PUNCT
fnp-5809	156	28	particularly	particularly	ADV
fnp-5809	156	29	for	for	ADP
fnp-5809	156	30	the	the	DET
fnp-5809	156	31	children	child	NOUN
fnp-5809	156	32	histologically	histologically	ADV
fnp-5809	156	33	displaying	display	VERB
fnp-5809	156	34	tumors	tumor	NOUN
fnp-5809	156	35	with	with	ADP
fnp-5809	156	36	characteristics	characteristic	NOUN
fnp-5809	156	37	of	of	ADP
fnp-5809	156	38	a	a	DET
fnp-5809	156	39	high	high	ADJ
fnp-5809	156	40	-	-	PUNCT
fnp-5809	156	41	grade	grade	NOUN
fnp-5809	156	42	glioma	glioma	NOUN
fnp-5809	156	43	.	.	PUNCT
fnp-5809	157	1	taken	take	VERB
fnp-5809	157	2	into	into	ADP
fnp-5809	157	3	account	account	NOUN
fnp-5809	157	4	that	that	SCONJ
fnp-5809	157	5	clinical	clinical	ADJ
fnp-5809	157	6	follow	follow	NOUN
fnp-5809	157	7	-	-	PUNCT
fnp-5809	157	8	up	up	NOUN
fnp-5809	157	9	revealed	reveal	VERB
fnp-5809	157	10	that	that	SCONJ
fnp-5809	157	11	molecular	molecular	ADJ
fnp-5809	157	12	profiling	profiling	NOUN
fnp-5809	157	13	provides	provide	VERB
fnp-5809	157	14	a	a	DET
fnp-5809	157	15	better	well	ADJ
fnp-5809	157	16	clinical	clinical	ADJ
fnp-5809	157	17	prediction	prediction	NOUN
fnp-5809	157	18	for	for	ADP
fnp-5809	157	19	patient	patient	ADJ
fnp-5809	157	20	prognosis	prognosis	NOUN
fnp-5809	157	21	than	than	ADP
fnp-5809	157	22	morphological	morphological	ADJ
fnp-5809	157	23	assessment	assessment	NOUN
fnp-5809	157	24	,	,	PUNCT
fnp-5809	157	25	it	it	PRON
fnp-5809	157	26	was	be	AUX
fnp-5809	157	27	highly	highly	ADV
fnp-5809	157	28	recommended	recommend	VERB
fnp-5809	157	29	to	to	PART
fnp-5809	157	30	implement	implement	VERB
fnp-5809	157	31	multiomics	multiomics	NOUN
fnp-5809	157	32	neuropathological	neuropathological	ADJ
fnp-5809	157	33	assessment	assessment	NOUN
fnp-5809	157	34	in	in	ADP
fnp-5809	157	35	the	the	DET
fnp-5809	157	36	diagnostic	diagnostic	ADJ
fnp-5809	157	37	routine	routine	NOUN
fnp-5809	157	38	.	.	PUNCT
fnp-5809	158	1	the	the	DET
fnp-5809	158	2	present	present	ADJ
fnp-5809	158	3	study	study	NOUN
fnp-5809	158	4	still	still	ADV
fnp-5809	158	5	highlights	highlight	VERB
fnp-5809	158	6	the	the	DET
fnp-5809	158	7	importance	importance	NOUN
fnp-5809	158	8	of	of	ADP
fnp-5809	158	9	methylation	methylation	NOUN
fnp-5809	158	10	profiling	profiling	NOUN
fnp-5809	158	11	,	,	PUNCT
fnp-5809	158	12	as	as	SCONJ
fnp-5809	158	13	methylation	methylation	NOUN
fnp-5809	158	14	data	datum	NOUN
fnp-5809	158	15	being	be	AUX
fnp-5809	158	16	discordant	discordant	ADJ
fnp-5809	158	17	to	to	ADP
fnp-5809	158	18	the	the	DET
fnp-5809	158	19	initial	initial	ADJ
fnp-5809	158	20	neuropathological	neuropathological	ADJ
fnp-5809	158	21	diagnosis	diagnosis	NOUN
fnp-5809	158	22	was	be	AUX
fnp-5809	158	23	considered	consider	VERB
fnp-5809	158	24	as	as	ADP
fnp-5809	158	25	relevant	relevant	ADJ
fnp-5809	158	26	in	in	ADP
fnp-5809	158	27	up	up	ADP
fnp-5809	158	28	to	to	PART
fnp-5809	158	29	70	70	NUM
fnp-5809	158	30	 	 	SPACE
fnp-5809	158	31	%	%	NOUN
fnp-5809	158	32	of	of	ADP
fnp-5809	158	33	the	the	DET
fnp-5809	158	34	cases	case	NOUN
fnp-5809	158	35	discussed	discuss	VERB
fnp-5809	158	36	in	in	ADP
fnp-5809	158	37	interdisciplinary	interdisciplinary	ADJ
fnp-5809	158	38	tumor	tumor	NOUN
fnp-5809	158	39	boards	board	NOUN
fnp-5809	158	40	.	.	PUNCT
fnp-5809	159	1	a	a	DET
fnp-5809	159	2	very	very	ADV
fnp-5809	159	3	useful	useful	ADJ
fnp-5809	159	4	tool	tool	NOUN
fnp-5809	159	5	of	of	ADP
fnp-5809	159	6	the	the	DET
fnp-5809	159	7	study	study	NOUN
fnp-5809	159	8	is	be	AUX
fnp-5809	159	9	the	the	DET
fnp-5809	159	10	proposed	propose	VERB
fnp-5809	159	11	molecular	molecular	ADJ
fnp-5809	159	12	risk	risk	NOUN
fnp-5809	159	13	stratification	stratification	NOUN
fnp-5809	159	14	of	of	ADP
fnp-5809	159	15	pediatric	pediatric	ADJ
fnp-5809	159	16	high	high	ADJ
fnp-5809	159	17	-	-	PUNCT
fnp-5809	159	18	grade	grade	NOUN
fnp-5809	159	19	gliomas	glioma	NOUN
fnp-5809	159	20	that	that	PRON
fnp-5809	159	21	have	have	AUX
fnp-5809	159	22	been	be	AUX
fnp-5809	159	23	classified	classify	VERB
fnp-5809	159	24	according	accord	VERB
fnp-5809	159	25	to	to	ADP
fnp-5809	159	26	cns	cns	PROPN
fnp-5809	159	27	who	who	PRON
fnp-5809	159	28	grade	grade	VERB
fnp-5809	159	29	3–4	3–4	NUM
fnp-5809	159	30	(	(	PUNCT
fnp-5809	159	31	table	table	NOUN
fnp-5809	159	32	3	3	NUM
fnp-5809	159	33	)	)	PUNCT
fnp-5809	159	34	.	.	PUNCT
fnp-5809	160	1	although	although	SCONJ
fnp-5809	160	2	the	the	DET
fnp-5809	160	3	who	who	PRON
fnp-5809	160	4	classification	classification	NOUN
fnp-5809	160	5	would	would	AUX
fnp-5809	160	6	put	put	VERB
fnp-5809	160	7	such	such	ADJ
fnp-5809	160	8	tumors	tumor	NOUN
fnp-5809	160	9	in	in	ADP
fnp-5809	160	10	a	a	DET
fnp-5809	160	11	very	very	ADV
fnp-5809	160	12	similar	similar	ADJ
fnp-5809	160	13	biological	biological	ADJ
fnp-5809	160	14	class	class	NOUN
fnp-5809	160	15	,	,	PUNCT
fnp-5809	160	16	it	it	PRON
fnp-5809	160	17	has	have	VERB
fnp-5809	160	18	to	to	PART
fnp-5809	160	19	be	be	AUX
fnp-5809	160	20	taken	take	VERB
fnp-5809	160	21	into	into	ADP
fnp-5809	160	22	account	account	NOUN
fnp-5809	160	23	that	that	SCONJ
fnp-5809	160	24	their	their	PRON
fnp-5809	160	25	clinical	clinical	ADJ
fnp-5809	160	26	behavior	behavior	NOUN
fnp-5809	160	27	might	might	AUX
fnp-5809	160	28	be	be	AUX
fnp-5809	160	29	very	very	ADV
fnp-5809	160	30	different	different	ADJ
fnp-5809	160	31	and	and	CCONJ
fnp-5809	160	32	that	that	DET
fnp-5809	160	33	multiomics	multiomics	NOUN
fnp-5809	160	34	,	,	PUNCT
fnp-5809	160	35	in	in	ADP
fnp-5809	160	36	particular	particular	ADJ
fnp-5809	160	37	methylation	methylation	NOUN
fnp-5809	160	38	profiling	profiling	NOUN
fnp-5809	160	39	,	,	PUNCT
fnp-5809	160	40	provides	provide	VERB
fnp-5809	160	41	a	a	DET
fnp-5809	160	42	much	much	ADV
fnp-5809	160	43	more	more	ADV
fnp-5809	160	44	precise	precise	ADJ
fnp-5809	160	45	prediction	prediction	NOUN
fnp-5809	160	46	in	in	ADP
fnp-5809	160	47	those	those	DET
fnp-5809	160	48	cases	case	NOUN
fnp-5809	160	49	.	.	PUNCT
fnp-5809	161	1	of	of	ADP
fnp-5809	161	2	note	note	NOUN
fnp-5809	161	3	,	,	PUNCT
fnp-5809	161	4	the	the	DET
fnp-5809	161	5	highly	highly	ADV
fnp-5809	161	6	successful	successful	ADJ
fnp-5809	161	7	results	result	NOUN
fnp-5809	161	8	of	of	ADP
fnp-5809	161	9	the	the	DET
fnp-5809	161	10	present	present	ADJ
fnp-5809	161	11	study	study	NOUN
fnp-5809	161	12	further	far	ADV
fnp-5809	161	13	had	have	VERB
fnp-5809	161	14	a	a	DET
fnp-5809	161	15	strong	strong	ADJ
fnp-5809	161	16	impact	impact	NOUN
fnp-5809	161	17	on	on	ADP
fnp-5809	161	18	health	health	NOUN
fnp-5809	161	19	politics	politic	NOUN
fnp-5809	161	20	.	.	PUNCT
fnp-5809	162	1	german	german	ADJ
fnp-5809	162	2	national	national	PROPN
fnp-5809	162	3	health	health	PROPN
fnp-5809	162	4	insurances	insurance	NOUN
fnp-5809	162	5	now	now	ADV
fnp-5809	162	6	provide	provide	VERB
fnp-5809	162	7	financing	financing	NOUN
fnp-5809	162	8	for	for	ADP
fnp-5809	162	9	dna	dna	PROPN
fnp-5809	162	10	methylation	methylation	NOUN
fnp-5809	162	11	profiling	profiling	NOUN
fnp-5809	162	12	and	and	CCONJ
fnp-5809	162	13	gene	gene	NOUN
fnp-5809	162	14	panel	panel	NOUN
fnp-5809	162	15	sequencing	sequence	VERB
fnp-5809	162	16	(	(	PUNCT
fnp-5809	162	17	for	for	ADP
fnp-5809	162	18	the	the	DET
fnp-5809	162	19	latter	latter	ADJ
fnp-5809	162	20	in	in	ADP
fnp-5809	162	21	both	both	CCONJ
fnp-5809	162	22	tumor	tumor	NOUN
fnp-5809	162	23	and	and	CCONJ
fnp-5809	162	24	blood	blood	NOUN
fnp-5809	162	25	leukocyte	leukocyte	NOUN
fnp-5809	162	26	samples	sample	NOUN
fnp-5809	162	27	)	)	PUNCT
fnp-5809	162	28	in	in	ADP
fnp-5809	162	29	parallel	parallel	NOUN
fnp-5809	162	30	for	for	ADP
fnp-5809	162	31	every	every	DET
fnp-5809	162	32	newly	newly	ADV
fnp-5809	162	33	diagnosed	diagnose	VERB
fnp-5809	162	34	brain	brain	NOUN
fnp-5809	162	35	tumor	tumor	NOUN
fnp-5809	162	36	case	case	NOUN
fnp-5809	162	37	in	in	ADP
fnp-5809	162	38	children	child	NOUN
fnp-5809	162	39	and	and	CCONJ
fnp-5809	162	40	adolescents	adolescent	NOUN
fnp-5809	162	41	,	,	PUNCT
fnp-5809	162	42	thereby	thereby	ADV
fnp-5809	162	43	changing	change	VERB
fnp-5809	162	44	the	the	DET
fnp-5809	162	45	standard	standard	NOUN
fnp-5809	162	46	-	-	PUNCT
fnp-5809	162	47	of	of	ADP
fnp-5809	162	48	-	-	PUNCT
fnp-5809	162	49	care	care	NOUN
fnp-5809	162	50	.	.	PUNCT
fnp-5809	163	1	table	table	NOUN
fnp-5809	163	2	3	3	NUM
fnp-5809	163	3	:	:	PUNCT
fnp-5809	163	4	molecular	molecular	ADJ
fnp-5809	163	5	risk	risk	NOUN
fnp-5809	163	6	stratification	stratification	NOUN
fnp-5809	163	7	classes	class	NOUN
fnp-5809	163	8	for	for	ADP
fnp-5809	163	9	of	of	ADP
fnp-5809	163	10	pediatric	pediatric	ADJ
fnp-5809	163	11	high	high	ADJ
fnp-5809	163	12	-	-	PUNCT
fnp-5809	163	13	grade	grade	NOUN
fnp-5809	163	14	gliomas	glioma	NOUN
fnp-5809	163	15	otherwise	otherwise	ADV
fnp-5809	163	16	classified	classify	VERB
fnp-5809	163	17	according	accord	VERB
fnp-5809	163	18	to	to	ADP
fnp-5809	163	19	cns	cns	PROPN
fnp-5809	163	20	who	who	PRON
fnp-5809	163	21	grade	grade	VERB
fnp-5809	163	22	3–4	3–4	NUM
fnp-5809	163	23	.	.	PUNCT
fnp-5809	164	1	the	the	DET
fnp-5809	164	2	molecular	molecular	ADJ
fnp-5809	164	3	risk	risk	NOUN
fnp-5809	164	4	remains	remain	VERB
fnp-5809	164	5	unknown	unknown	ADJ
fnp-5809	164	6	for	for	ADP
fnp-5809	164	7	cases	case	NOUN
fnp-5809	164	8	revealing	reveal	VERB
fnp-5809	164	9	high	high	ADJ
fnp-5809	164	10	score	score	NOUN
fnp-5809	164	11	for	for	ADP
fnp-5809	164	12	non	non	ADJ
fnp-5809	164	13	-	-	ADJ
fnp-5809	164	14	neoplastic	neoplastic	ADJ
fnp-5809	164	15	control	control	NOUN
fnp-5809	164	16	tissue	tissue	NOUN
fnp-5809	164	17	or	or	CCONJ
fnp-5809	164	18	being	be	AUX
fnp-5809	164	19	unclassifiable	unclassifiable	ADJ
fnp-5809	164	20	in	in	ADP
fnp-5809	164	21	the	the	DET
fnp-5809	164	22	dna	dna	PROPN
fnp-5809	164	23	methylation	methylation	NOUN
fnp-5809	164	24	classifier	classifier	NOUN
fnp-5809	164	25	.	.	PUNCT
fnp-5809	165	1	as	as	SCONJ
fnp-5809	165	2	the	the	DET
fnp-5809	165	3	biological	biological	ADJ
fnp-5809	165	4	behavior	behavior	NOUN
fnp-5809	165	5	is	be	AUX
fnp-5809	165	6	still	still	ADV
fnp-5809	165	7	unclear	unclear	ADJ
fnp-5809	165	8	for	for	ADP
fnp-5809	165	9	pediatric	pediatric	ADJ
fnp-5809	165	10	brain	brain	NOUN
fnp-5809	165	11	tumor	tumor	NOUN
fnp-5809	165	12	with	with	ADP
fnp-5809	165	13	patz1	patz1	PROPN
fnp-5809	165	14	or	or	CCONJ
fnp-5809	165	15	plagl1	plagl1	PROPN
fnp-5809	165	16	fusion	fusion	NOUN
fnp-5809	165	17	,	,	PUNCT
fnp-5809	165	18	those	those	DET
fnp-5809	165	19	tumors	tumor	NOUN
fnp-5809	165	20	were	be	AUX
fnp-5809	165	21	excluded	exclude	VERB
fnp-5809	165	22	from	from	ADP
fnp-5809	165	23	the	the	DET
fnp-5809	165	24	risk	risk	NOUN
fnp-5809	165	25	stratification	stratification	NOUN
fnp-5809	165	26	.	.	PUNCT
fnp-5809	166	1	9	9	X
fnp-5809	166	2	.	.	X
fnp-5809	166	3	clinical	clinical	ADJ
fnp-5809	166	4	vaccination	vaccination	NOUN
fnp-5809	166	5	study	study	NOUN
fnp-5809	166	6	targeting	target	VERB
fnp-5809	166	7	h3k27	h3k27	PRON
fnp-5809	166	8	m	m	VERB
fnp-5809	166	9	in	in	ADP
fnp-5809	166	10	adult	adult	NOUN
fnp-5809	166	11	diffuse	diffuse	NOUN
fnp-5809	166	12	midline	midline	NOUN
fnp-5809	166	13	glioma	glioma	NOUN
fnp-5809	167	1	[	[	X
fnp-5809	167	2	grassl	grassl	VERB
fnp-5809	167	3	et	et	PROPN
fnp-5809	167	4	al	al	PROPN
fnp-5809	167	5	.	.	PROPN
fnp-5809	167	6	,	,	PUNCT
fnp-5809	167	7	2023	2023	NUM
fnp-5809	167	8	]	]	PUNCT
fnp-5809	167	9	.	.	PUNCT
fnp-5809	168	1	while	while	SCONJ
fnp-5809	168	2	mutations	mutation	NOUN
fnp-5809	168	3	in	in	ADP
fnp-5809	168	4	histone	histone	NOUN
fnp-5809	168	5	h3	h3	NOUN
fnp-5809	168	6	have	have	AUX
fnp-5809	168	7	been	be	AUX
fnp-5809	168	8	detected	detect	VERB
fnp-5809	168	9	in	in	ADP
fnp-5809	168	10	several	several	ADJ
fnp-5809	168	11	human	human	ADJ
fnp-5809	168	12	tumors	tumor	NOUN
fnp-5809	168	13	,	,	PUNCT
fnp-5809	168	14	the	the	DET
fnp-5809	168	15	h3k27	h3k27	NOUN
fnp-5809	168	16	m	m	NOUN
fnp-5809	168	17	mutation	mutation	NOUN
fnp-5809	168	18	in	in	ADP
fnp-5809	168	19	diffuse	diffuse	ADJ
fnp-5809	168	20	gliomas	glioma	NOUN
fnp-5809	168	21	of	of	ADP
fnp-5809	168	22	mainly	mainly	ADV
fnp-5809	168	23	younger	young	ADJ
fnp-5809	168	24	patients	patient	NOUN
fnp-5809	168	25	constitutes	constitute	VERB
fnp-5809	168	26	a	a	DET
fnp-5809	168	27	specific	specific	ADJ
fnp-5809	168	28	brain	brain	NOUN
fnp-5809	168	29	tumor	tumor	NOUN
fnp-5809	168	30	entity	entity	NOUN
fnp-5809	168	31	usually	usually	ADV
fnp-5809	168	32	showing	show	VERB
fnp-5809	168	33	a	a	DET
fnp-5809	168	34	detrimental	detrimental	ADJ
fnp-5809	168	35	clinical	clinical	ADJ
fnp-5809	168	36	prognosis	prognosis	NOUN
fnp-5809	168	37	[	[	X
fnp-5809	168	38	who	who	PRON
fnp-5809	168	39	classification	classification	NOUN
fnp-5809	168	40	of	of	ADP
fnp-5809	168	41	brain	brain	NOUN
fnp-5809	168	42	tumors	tumor	NOUN
fnp-5809	168	43	,	,	PUNCT
fnp-5809	168	44	2021	2021	NUM
fnp-5809	168	45	]	]	PUNCT
fnp-5809	168	46	.	.	PUNCT
fnp-5809	169	1	although	although	SCONJ
fnp-5809	169	2	,	,	PUNCT
fnp-5809	169	3	h3k27	h3k27	PRON
fnp-5809	169	4	m	m	VERB
fnp-5809	169	5	mutant	mutant	ADJ
fnp-5809	169	6	diffuse	diffuse	NOUN
fnp-5809	169	7	midline	midline	NOUN
fnp-5809	169	8	gliomas	glioma	NOUN
fnp-5809	169	9	are	be	AUX
fnp-5809	169	10	incurable	incurable	ADJ
fnp-5809	169	11	,	,	PUNCT
fnp-5809	169	12	the	the	DET
fnp-5809	169	13	first	first	ADJ
fnp-5809	169	14	promising	promising	ADJ
fnp-5809	169	15	results	result	NOUN
fnp-5809	169	16	were	be	AUX
fnp-5809	169	17	obtained	obtain	VERB
fnp-5809	169	18	from	from	ADP
fnp-5809	169	19	mhc	mhc	PROPN
fnp-5809	169	20	-	-	PUNCT
fnp-5809	169	21	humanized	humanize	VERB
fnp-5809	169	22	mice	mouse	NOUN
fnp-5809	169	23	showing	show	VERB
fnp-5809	169	24	a	a	DET
fnp-5809	169	25	mutation	mutation	NOUN
fnp-5809	169	26	specific	specific	ADJ
fnp-5809	169	27	immune	immune	ADJ
fnp-5809	169	28	response	response	NOUN
fnp-5809	169	29	to	to	ADP
fnp-5809	169	30	a	a	DET
fnp-5809	169	31	h3k27	h3k27	ADJ
fnp-5809	169	32	m	m	NOUN
fnp-5809	169	33	long	long	ADJ
fnp-5809	169	34	peptide	peptide	ADJ
fnp-5809	169	35	vaccine	vaccine	NOUN
fnp-5809	170	1	[	[	X
fnp-5809	170	2	ochs	och	NOUN
fnp-5809	170	3	et	et	NOUN
fnp-5809	170	4	al	al	PROPN
fnp-5809	170	5	.	.	PROPN
fnp-5809	170	6	,	,	PUNCT
fnp-5809	170	7	2017	2017	NUM
fnp-5809	170	8	]	]	PUNCT
fnp-5809	170	9	.	.	PUNCT
fnp-5809	171	1	this	this	PRON
fnp-5809	171	2	prompted	prompt	VERB
fnp-5809	171	3	the	the	DET
fnp-5809	171	4	authors	author	NOUN
fnp-5809	171	5	to	to	PART
fnp-5809	171	6	start	start	VERB
fnp-5809	171	7	a	a	DET
fnp-5809	171	8	phase	phase	NOUN
fnp-5809	171	9	i	i	PRON
fnp-5809	171	10	clinical	clinical	ADJ
fnp-5809	171	11	trial	trial	NOUN
fnp-5809	171	12	with	with	ADP
fnp-5809	171	13	8	8	NUM
fnp-5809	171	14	patients	patient	NOUN
fnp-5809	171	15	suffering	suffer	VERB
fnp-5809	171	16	from	from	ADP
fnp-5809	171	17	a	a	DET
fnp-5809	171	18	h3k27m	h3k27m	PROPN
fnp-5809	171	19	-	-	ADJ
fnp-5809	171	20	positive	positive	ADJ
fnp-5809	171	21	diffuse	diffuse	NOUN
fnp-5809	171	22	midline	midline	NOUN
fnp-5809	171	23	glioma	glioma	NOUN
fnp-5809	172	1	[	[	X
fnp-5809	172	2	grassl	grassl	VERB
fnp-5809	172	3	et	et	PROPN
fnp-5809	172	4	al	al	PROPN
fnp-5809	172	5	.	.	PROPN
fnp-5809	172	6	,	,	PUNCT
fnp-5809	172	7	2023	2023	NUM
fnp-5809	172	8	]	]	PUNCT
fnp-5809	172	9	.	.	PUNCT
fnp-5809	173	1	all	all	DET
fnp-5809	173	2	patients	patient	NOUN
fnp-5809	173	3	received	receive	VERB
fnp-5809	173	4	a	a	DET
fnp-5809	173	5	27	27	NUM
fnp-5809	173	6	-	-	PUNCT
fnp-5809	173	7	mer	mer	NOUN
fnp-5809	173	8	peptide	peptide	NOUN
fnp-5809	173	9	(	(	PUNCT
fnp-5809	173	10	p14	p14	PROPN
fnp-5809	173	11	-	-	PUNCT
fnp-5809	173	12	40	40	NUM
fnp-5809	173	13	)	)	PUNCT
fnp-5809	173	14	including	include	VERB
fnp-5809	173	15	the	the	DET
fnp-5809	173	16	mutant	mutant	NOUN
fnp-5809	173	17	h3k27	h3k27	NOUN
fnp-5809	173	18	m	m	VERB
fnp-5809	173	19	via	via	ADP
fnp-5809	173	20	bi	bi	ADJ
fnp-5809	173	21	-	-	ADJ
fnp-5809	173	22	weekly	weekly	ADJ
fnp-5809	173	23	subcutaneous	subcutaneous	ADJ
fnp-5809	173	24	injection	injection	NOUN
fnp-5809	173	25	over	over	ADP
fnp-5809	173	26	6	6	NUM
fnp-5809	173	27	weeks	week	NOUN
fnp-5809	173	28	followed	follow	VERB
fnp-5809	173	29	by	by	ADP
fnp-5809	173	30	monthly	monthly	ADJ
fnp-5809	173	31	administration	administration	NOUN
fnp-5809	173	32	for	for	ADP
fnp-5809	173	33	4	4	NUM
fnp-5809	173	34	months	month	NOUN
fnp-5809	173	35	and	and	CCONJ
fnp-5809	173	36	quarterly	quarterly	ADJ
fnp-5809	173	37	afterwards	afterwards	ADV
fnp-5809	173	38	until	until	ADP
fnp-5809	173	39	disease	disease	NOUN
fnp-5809	173	40	progression	progression	NOUN
fnp-5809	173	41	.	.	PUNCT
fnp-5809	174	1	the	the	DET
fnp-5809	174	2	vaccine	vaccine	NOUN
fnp-5809	174	3	was	be	AUX
fnp-5809	174	4	well	well	ADV
fnp-5809	174	5	tolerated	tolerate	VERB
fnp-5809	174	6	and	and	CCONJ
fnp-5809	174	7	without	without	ADP
fnp-5809	174	8	any	any	DET
fnp-5809	174	9	relevant	relevant	ADJ
fnp-5809	174	10	higher	high	ADJ
fnp-5809	174	11	-	-	PUNCT
fnp-5809	174	12	grade	grade	NOUN
fnp-5809	174	13	side	side	NOUN
fnp-5809	174	14	effects	effect	NOUN
fnp-5809	174	15	.	.	PUNCT
fnp-5809	175	1	after	after	ADP
fnp-5809	175	2	2	2	NUM
fnp-5809	175	3	injections	injection	NOUN
fnp-5809	175	4	,	,	PUNCT
fnp-5809	175	5	h3k27m	h3k27m	NOUN
fnp-5809	175	6	-	-	PUNCT
fnp-5809	175	7	vaccine	vaccine	NOUN
fnp-5809	175	8	related	relate	VERB
fnp-5809	175	9	neoepitope	neoepitope	NOUN
fnp-5809	175	10	-	-	PUNCT
fnp-5809	175	11	specific	specific	ADJ
fnp-5809	175	12	immune	immune	ADJ
fnp-5809	175	13	responses	response	NOUN
fnp-5809	175	14	(	(	PUNCT
fnp-5809	175	15	in	in	ADP
fnp-5809	175	16	blood	blood	NOUN
fnp-5809	175	17	and	and	CCONJ
fnp-5809	175	18	csf	csf	NOUN
fnp-5809	175	19	)	)	PUNCT
fnp-5809	175	20	were	be	AUX
fnp-5809	175	21	detected	detect	VERB
fnp-5809	175	22	in	in	ADP
fnp-5809	175	23	5	5	NUM
fnp-5809	175	24	out	out	ADP
fnp-5809	175	25	of	of	ADP
fnp-5809	175	26	8	8	NUM
fnp-5809	175	27	patients	patient	NOUN
fnp-5809	175	28	and	and	CCONJ
fnp-5809	175	29	were	be	AUX
fnp-5809	175	30	associated	associate	VERB
fnp-5809	175	31	with	with	ADP
fnp-5809	175	32	promising	promising	ADJ
fnp-5809	175	33	neuroradiological	neuroradiological	ADJ
fnp-5809	175	34	findings	finding	NOUN
fnp-5809	175	35	showing	show	VERB
fnp-5809	175	36	reduced	reduce	VERB
fnp-5809	175	37	axial	axial	ADJ
fnp-5809	175	38	contrast	contrast	NOUN
fnp-5809	175	39	enhancement	enhancement	NOUN
fnp-5809	175	40	.	.	PUNCT
fnp-5809	176	1	for	for	ADP
fnp-5809	176	2	patients	patient	NOUN
fnp-5809	176	3	from	from	ADP
fnp-5809	176	4	which	which	PRON
fnp-5809	176	5	previous	previous	ADJ
fnp-5809	176	6	tumor	tumor	NOUN
fnp-5809	176	7	material	material	NOUN
fnp-5809	176	8	was	be	AUX
fnp-5809	176	9	accessible	accessible	ADJ
fnp-5809	176	10	,	,	PUNCT
fnp-5809	176	11	a	a	DET
fnp-5809	176	12	colocalization	colocalization	NOUN
fnp-5809	176	13	of	of	ADP
fnp-5809	176	14	mutant	mutant	NOUN
fnp-5809	176	15	h3k27	h3k27	NOUN
fnp-5809	176	16	m	m	PROPN
fnp-5809	176	17	and	and	CCONJ
fnp-5809	176	18	hla	hla	PROPN
fnp-5809	176	19	class	class	NOUN
fnp-5809	176	20	-	-	PUNCT
fnp-5809	176	21	ii	ii	NOUN
fnp-5809	176	22	-	-	PROPN
fnp-5809	176	23	dr	dr	PROPN
fnp-5809	176	24	was	be	AUX
fnp-5809	176	25	detected	detect	VERB
fnp-5809	176	26	,	,	PUNCT
fnp-5809	176	27	indicating	indicate	VERB
fnp-5809	176	28	that	that	SCONJ
fnp-5809	176	29	the	the	DET
fnp-5809	176	30	neoepitope	neoepitope	NOUN
fnp-5809	176	31	is	be	AUX
fnp-5809	176	32	probably	probably	ADV
fnp-5809	176	33	presented	present	VERB
fnp-5809	176	34	by	by	ADP
fnp-5809	176	35	antigen	antigen	ADV
fnp-5809	176	36	-	-	PUNCT
fnp-5809	176	37	presenting	present	VERB
fnp-5809	176	38	cells	cell	NOUN
fnp-5809	176	39	which	which	PRON
fnp-5809	176	40	might	might	AUX
fnp-5809	176	41	lead	lead	VERB
fnp-5809	176	42	to	to	ADP
fnp-5809	176	43	a	a	DET
fnp-5809	176	44	stimulation	stimulation	NOUN
fnp-5809	176	45	of	of	ADP
fnp-5809	176	46	h3k27m	h3k27m	NOUN
fnp-5809	176	47	-	-	ADJ
fnp-5809	176	48	specific	specific	ADJ
fnp-5809	176	49	t	t	NOUN
fnp-5809	176	50	cells	cell	NOUN
fnp-5809	176	51	.	.	PUNCT
fnp-5809	177	1	of	of	ADP
fnp-5809	177	2	note	note	NOUN
fnp-5809	177	3	,	,	PUNCT
fnp-5809	177	4	the	the	DET
fnp-5809	177	5	two	two	NUM
fnp-5809	177	6	patients	patient	NOUN
fnp-5809	177	7	of	of	ADP
fnp-5809	177	8	this	this	DET
fnp-5809	177	9	phase	phase	NOUN
fnp-5809	177	10	i	i	PRON
fnp-5809	177	11	study	study	VERB
fnp-5809	177	12	with	with	ADP
fnp-5809	177	13	the	the	DET
fnp-5809	177	14	best	good	ADJ
fnp-5809	177	15	clinical	clinical	ADJ
fnp-5809	177	16	outcome	outcome	NOUN
fnp-5809	177	17	after	after	ADP
fnp-5809	177	18	detection	detection	NOUN
fnp-5809	177	19	of	of	ADP
fnp-5809	177	20	peripheral	peripheral	ADJ
fnp-5809	177	21	immune	immune	ADJ
fnp-5809	177	22	response	response	NOUN
fnp-5809	177	23	also	also	ADV
fnp-5809	177	24	showed	show	VERB
fnp-5809	177	25	highest	high	ADJ
fnp-5809	177	26	numbers	number	NOUN
fnp-5809	177	27	of	of	ADP
fnp-5809	177	28	hla	hla	PROPN
fnp-5809	177	29	class	class	NOUN
fnp-5809	177	30	-	-	PUNCT
fnp-5809	177	31	ii	ii	PROPN
fnp-5809	177	32	-	-	PUNCT
fnp-5809	177	33	dr	dr	ADJ
fnp-5809	177	34	-	-	ADJ
fnp-5809	177	35	positive	positive	ADJ
fnp-5809	177	36	cells	cell	NOUN
fnp-5809	177	37	associated	associate	VERB
fnp-5809	177	38	with	with	ADP
fnp-5809	177	39	mutant	mutant	ADJ
fnp-5809	177	40	h3k27	h3k27	NOUN
fnp-5809	177	41	m	m	VERB
fnp-5809	177	42	which	which	PRON
fnp-5809	177	43	may	may	AUX
fnp-5809	177	44	indicate	indicate	VERB
fnp-5809	177	45	that	that	SCONJ
fnp-5809	177	46	enhanced	enhance	VERB
fnp-5809	177	47	immune	immune	ADJ
fnp-5809	177	48	cell	cell	NOUN
fnp-5809	177	49	responses	response	NOUN
fnp-5809	177	50	associated	associate	VERB
fnp-5809	177	51	with	with	ADP
fnp-5809	177	52	mutant	mutant	ADJ
fnp-5809	177	53	neoepitope	neoepitope	NOUN
fnp-5809	177	54	presentation	presentation	NOUN
fnp-5809	177	55	are	be	AUX
fnp-5809	177	56	responsible	responsible	ADJ
fnp-5809	177	57	for	for	ADP
fnp-5809	177	58	better	well	ADJ
fnp-5809	177	59	patient	patient	ADJ
fnp-5809	177	60	prognosis	prognosis	NOUN
fnp-5809	177	61	.	.	PUNCT
fnp-5809	178	1	with	with	ADP
fnp-5809	178	2	this	this	DET
fnp-5809	178	3	first	first	ADJ
fnp-5809	178	4	human	human	ADJ
fnp-5809	178	5	vaccination	vaccination	NOUN
fnp-5809	178	6	trial	trial	NOUN
fnp-5809	178	7	for	for	ADP
fnp-5809	178	8	h3k27	h3k27	NOUN
fnp-5809	178	9	m	m	NOUN
fnp-5809	178	10	mutant	mutant	ADJ
fnp-5809	178	11	diffuse	diffuse	ADJ
fnp-5809	178	12	midline	midline	NOUN
fnp-5809	178	13	glioma	glioma	NOUN
fnp-5809	178	14	,	,	PUNCT
fnp-5809	178	15	the	the	DET
fnp-5809	178	16	authors	author	NOUN
fnp-5809	178	17	demonstrated	demonstrate	VERB
fnp-5809	178	18	patient	patient	ADJ
fnp-5809	178	19	safety	safety	NOUN
fnp-5809	178	20	and	and	CCONJ
fnp-5809	178	21	neoepitope	neoepitope	NOUN
fnp-5809	178	22	immune	immune	ADJ
fnp-5809	178	23	responses	response	NOUN
fnp-5809	178	24	.	.	PUNCT
fnp-5809	179	1	as	as	ADP
fnp-5809	179	2	a	a	DET
fnp-5809	179	3	most	most	ADV
fnp-5809	179	4	promising	promising	ADJ
fnp-5809	179	5	finding	finding	NOUN
fnp-5809	179	6	,	,	PUNCT
fnp-5809	179	7	complete	complete	ADJ
fnp-5809	179	8	remission	remission	NOUN
fnp-5809	179	9	for	for	ADP
fnp-5809	179	10	more	more	ADJ
fnp-5809	179	11	than	than	ADP
fnp-5809	179	12	31	31	NUM
fnp-5809	179	13	months	month	NOUN
fnp-5809	179	14	was	be	AUX
fnp-5809	179	15	achieved	achieve	VERB
fnp-5809	179	16	in	in	ADP
fnp-5809	179	17	one	one	NUM
fnp-5809	179	18	patient	patient	NOUN
fnp-5809	179	19	.	.	PUNCT
fnp-5809	180	1	however	however	ADV
fnp-5809	180	2	,	,	PUNCT
fnp-5809	180	3	all	all	DET
fnp-5809	180	4	other	other	ADJ
fnp-5809	180	5	patients	patient	NOUN
fnp-5809	180	6	died	die	VERB
fnp-5809	180	7	within	within	ADP
fnp-5809	180	8	the	the	DET
fnp-5809	180	9	study	study	NOUN
fnp-5809	180	10	period	period	NOUN
fnp-5809	180	11	.	.	PUNCT
fnp-5809	181	1	to	to	PART
fnp-5809	181	2	further	far	ADV
fnp-5809	181	3	improve	improve	VERB
fnp-5809	181	4	the	the	DET
fnp-5809	181	5	h3k27	h3k27	PROPN
fnp-5809	181	6	m	m	NOUN
fnp-5809	181	7	vaccine	vaccine	NOUN
fnp-5809	181	8	-	-	PUNCT
fnp-5809	181	9	based	base	VERB
fnp-5809	181	10	effects	effect	NOUN
fnp-5809	181	11	,	,	PUNCT
fnp-5809	181	12	the	the	DET
fnp-5809	181	13	authors	author	NOUN
fnp-5809	181	14	propose	propose	VERB
fnp-5809	181	15	to	to	PART
fnp-5809	181	16	administer	administer	VERB
fnp-5809	181	17	the	the	DET
fnp-5809	181	18	vaccine	vaccine	NOUN
fnp-5809	181	19	concomitantly	concomitantly	ADV
fnp-5809	181	20	with	with	ADP
fnp-5809	181	21	first	first	ADJ
fnp-5809	181	22	line	line	NOUN
fnp-5809	181	23	treatment	treatment	NOUN
fnp-5809	181	24	to	to	PART
fnp-5809	181	25	increase	increase	VERB
fnp-5809	181	26	the	the	DET
fnp-5809	181	27	time	time	NOUN
fnp-5809	181	28	for	for	SCONJ
fnp-5809	181	29	t	t	PROPN
fnp-5809	181	30	cell	cell	NOUN
fnp-5809	181	31	mediated	mediate	VERB
fnp-5809	181	32	antitumoral	antitumoral	ADJ
fnp-5809	181	33	effects	effect	NOUN
fnp-5809	181	34	.	.	PUNCT
fnp-5809	182	1	10	10	NUM
fnp-5809	182	2	.	.	PUNCT
fnp-5809	182	3	clinical	clinical	ADJ
fnp-5809	182	4	study	study	NOUN
fnp-5809	182	5	in	in	ADP
fnp-5809	182	6	patients	patient	NOUN
fnp-5809	182	7	with	with	ADP
fnp-5809	182	8	idh	idh	NOUN
fnp-5809	182	9	mutant	mutant	ADJ
fnp-5809	182	10	low	low	ADJ
fnp-5809	182	11	-	-	PUNCT
fnp-5809	182	12	grade	grade	NOUN
fnp-5809	182	13	glioma	glioma	NOUN
fnp-5809	182	14	using	use	VERB
fnp-5809	182	15	an	an	DET
fnp-5809	182	16	oral	oral	ADJ
fnp-5809	182	17	,	,	PUNCT
fnp-5809	182	18	brain	brain	NOUN
fnp-5809	182	19	-	-	PUNCT
fnp-5809	182	20	penetrant	penetrant	NOUN
fnp-5809	182	21	inhibitor	inhibitor	NOUN
fnp-5809	182	22	of	of	ADP
fnp-5809	182	23	mutant	mutant	ADJ
fnp-5809	182	24	idh1	idh1	PROPN
fnp-5809	182	25	and	and	CCONJ
fnp-5809	182	26	idh2	idh2	PROPN
fnp-5809	182	27	enzymes	enzyme	NOUN
fnp-5809	183	1	[	[	X
fnp-5809	183	2	mellinghoff	mellinghoff	X
fnp-5809	183	3	et	et	PROPN
fnp-5809	183	4	al	al	PROPN
fnp-5809	183	5	.	.	PROPN
fnp-5809	183	6	,	,	PUNCT
fnp-5809	183	7	2023	2023	NUM
fnp-5809	183	8	]	]	PUNCT
fnp-5809	183	9	.	.	PUNCT
fnp-5809	184	1	in	in	ADP
fnp-5809	184	2	2009	2009	NUM
fnp-5809	184	3	,	,	PUNCT
fnp-5809	184	4	the	the	DET
fnp-5809	184	5	detection	detection	NOUN
fnp-5809	184	6	of	of	ADP
fnp-5809	184	7	specific	specific	ADJ
fnp-5809	184	8	point	point	NOUN
fnp-5809	184	9	mutations	mutation	NOUN
fnp-5809	184	10	in	in	ADP
fnp-5809	184	11	idh1	idh1	PROPN
fnp-5809	184	12	and	and	CCONJ
fnp-5809	184	13	idh2	idh2	PROPN
fnp-5809	184	14	genes	gene	NOUN
fnp-5809	184	15	in	in	ADP
fnp-5809	184	16	distinct	distinct	ADJ
fnp-5809	184	17	brain	brain	NOUN
fnp-5809	184	18	tumor	tumor	NOUN
fnp-5809	184	19	entities	entity	NOUN
fnp-5809	184	20	,	,	PUNCT
fnp-5809	184	21	in	in	ADP
fnp-5809	184	22	particular	particular	ADJ
fnp-5809	184	23	diffuse	diffuse	NOUN
fnp-5809	184	24	astrocytoma	astrocytoma	NOUN
fnp-5809	184	25	and	and	CCONJ
fnp-5809	184	26	oligodendroglioma	oligodendroglioma	VERB
fnp-5809	184	27	,	,	PUNCT
fnp-5809	184	28	considerably	considerably	ADV
fnp-5809	184	29	changed	change	VERB
fnp-5809	184	30	the	the	DET
fnp-5809	184	31	neuropathological	neuropathological	ADJ
fnp-5809	184	32	diagnostic	diagnostic	ADJ
fnp-5809	184	33	approach	approach	NOUN
fnp-5809	184	34	paving	pave	VERB
fnp-5809	184	35	the	the	DET
fnp-5809	184	36	way	way	NOUN
fnp-5809	184	37	from	from	ADP
fnp-5809	184	38	a	a	DET
fnp-5809	184	39	mainly	mainly	ADV
fnp-5809	184	40	histological	histological	ADJ
fnp-5809	184	41	to	to	ADP
fnp-5809	184	42	a	a	DET
fnp-5809	184	43	more	more	ADJ
fnp-5809	184	44	and	and	CCONJ
fnp-5809	184	45	more	more	ADV
fnp-5809	184	46	molecular	molecular	ADJ
fnp-5809	184	47	classification	classification	NOUN
fnp-5809	184	48	[	[	X
fnp-5809	184	49	yan	yan	X
fnp-5809	184	50	et	et	PROPN
fnp-5809	184	51	al	al	PROPN
fnp-5809	184	52	.	.	PROPN
fnp-5809	184	53	,	,	PUNCT
fnp-5809	184	54	2009	2009	NUM
fnp-5809	184	55	]	]	PUNCT
fnp-5809	184	56	.	.	PUNCT
fnp-5809	185	1	the	the	DET
fnp-5809	185	2	most	most	ADV
fnp-5809	185	3	frequently	frequently	ADV
fnp-5809	185	4	altered	alter	VERB
fnp-5809	185	5	amino	amino	NOUN
fnp-5809	185	6	acid	acid	NOUN
fnp-5809	185	7	is	be	AUX
fnp-5809	185	8	132	132	NUM
fnp-5809	185	9	in	in	ADP
fnp-5809	185	10	idh1	idh1	PROPN
fnp-5809	185	11	and	and	CCONJ
fnp-5809	185	12	172	172	NUM
fnp-5809	185	13	in	in	ADP
fnp-5809	185	14	idh2	idh2	PROPN
fnp-5809	185	15	.	.	PUNCT
fnp-5809	186	1	thus	thus	ADV
fnp-5809	186	2	,	,	PUNCT
fnp-5809	186	3	those	those	DET
fnp-5809	186	4	alterations	alteration	NOUN
fnp-5809	186	5	make	make	VERB
fnp-5809	186	6	them	they	PRON
fnp-5809	186	7	a	a	DET
fnp-5809	186	8	promising	promising	ADJ
fnp-5809	186	9	treatment	treatment	NOUN
fnp-5809	186	10	target	target	NOUN
fnp-5809	186	11	.	.	PUNCT
fnp-5809	187	1	the	the	DET
fnp-5809	187	2	application	application	NOUN
fnp-5809	187	3	of	of	ADP
fnp-5809	187	4	the	the	DET
fnp-5809	187	5	dual	dual	ADJ
fnp-5809	187	6	idh1	idh1	NOUN
fnp-5809	187	7	and	and	CCONJ
fnp-5809	187	8	idh2	idh2	PROPN
fnp-5809	187	9	inhibitor	inhibitor	PROPN
fnp-5809	187	10	vorasidenib	vorasidenib	NOUN
fnp-5809	187	11	in	in	ADP
fnp-5809	187	12	an	an	DET
fnp-5809	187	13	orthotopic	orthotopic	ADJ
fnp-5809	187	14	murine	murine	ADJ
fnp-5809	187	15	glioma	glioma	NOUN
fnp-5809	187	16	model	model	NOUN
fnp-5809	187	17	showed	show	VERB
fnp-5809	187	18	considerably	considerably	ADV
fnp-5809	187	19	reduced	reduce	VERB
fnp-5809	187	20	2	2	NUM
fnp-5809	187	21	-	-	PUNCT
fnp-5809	187	22	hydroxyglutarate	hydroxyglutarate	NOUN
fnp-5809	187	23	levels	level	NOUN
fnp-5809	187	24	that	that	PRON
fnp-5809	187	25	acts	act	VERB
fnp-5809	187	26	as	as	ADP
fnp-5809	187	27	an	an	DET
fnp-5809	187	28	oncometabolite	oncometabolite	NOUN
fnp-5809	188	1	[	[	X
fnp-5809	188	2	konteatis	konteatis	PROPN
fnp-5809	188	3	et	et	PROPN
fnp-5809	188	4	al	al	PROPN
fnp-5809	188	5	.	.	PROPN
fnp-5809	188	6	,	,	PUNCT
fnp-5809	188	7	2020	2020	NUM
fnp-5809	188	8	]	]	PUNCT
fnp-5809	188	9	.	.	PUNCT
fnp-5809	189	1	in	in	ADP
fnp-5809	189	2	addition	addition	NOUN
fnp-5809	189	3	,	,	PUNCT
fnp-5809	189	4	it	it	PRON
fnp-5809	189	5	was	be	AUX
fnp-5809	189	6	demonstrated	demonstrate	VERB
fnp-5809	189	7	that	that	SCONJ
fnp-5809	189	8	vorasidenib	vorasidenib	NOUN
fnp-5809	189	9	also	also	ADV
fnp-5809	189	10	penetrated	penetrate	VERB
fnp-5809	189	11	the	the	DET
fnp-5809	189	12	brain	brain	NOUN
fnp-5809	189	13	of	of	ADP
fnp-5809	189	14	several	several	ADJ
fnp-5809	189	15	non	non	ADJ
fnp-5809	189	16	-	-	ADJ
fnp-5809	189	17	human	human	ADJ
fnp-5809	189	18	species	specie	NOUN
fnp-5809	189	19	therefore	therefore	ADV
fnp-5809	189	20	showing	show	VERB
fnp-5809	189	21	its	its	PRON
fnp-5809	189	22	cns	cns	NOUN
fnp-5809	189	23	bioavailability	bioavailability	NOUN
fnp-5809	189	24	in	in	ADP
fnp-5809	189	25	preclinical	preclinical	ADJ
fnp-5809	189	26	models	model	NOUN
fnp-5809	189	27	.	.	PUNCT
fnp-5809	190	1	this	this	PRON
fnp-5809	190	2	prompted	prompt	VERB
fnp-5809	190	3	several	several	ADJ
fnp-5809	190	4	neurooncological	neurooncological	ADJ
fnp-5809	190	5	teams	team	NOUN
fnp-5809	190	6	to	to	PART
fnp-5809	190	7	test	test	VERB
fnp-5809	190	8	idh1	idh1	PROPN
fnp-5809	190	9	/	/	SYM
fnp-5809	190	10	idh2	idh2	PROPN
fnp-5809	190	11	inhibitors	inhibitor	NOUN
fnp-5809	190	12	in	in	ADP
fnp-5809	190	13	the	the	DET
fnp-5809	190	14	clinical	clinical	ADJ
fnp-5809	190	15	context	context	NOUN
fnp-5809	190	16	of	of	ADP
fnp-5809	190	17	which	which	PRON
fnp-5809	190	18	the	the	DET
fnp-5809	190	19	double	double	ADJ
fnp-5809	190	20	-	-	PUNCT
fnp-5809	190	21	blind	blind	ADJ
fnp-5809	190	22	,	,	PUNCT
fnp-5809	190	23	phase	phase	NOUN
fnp-5809	190	24	3	3	NUM
fnp-5809	190	25	trial	trial	NOUN
fnp-5809	190	26	of	of	ADP
fnp-5809	190	27	mellinghoff	mellinghoff	NOUN
fnp-5809	190	28	and	and	CCONJ
fnp-5809	190	29	colleagues	colleague	NOUN
fnp-5809	190	30	is	be	AUX
fnp-5809	190	31	one	one	NUM
fnp-5809	190	32	of	of	ADP
fnp-5809	190	33	the	the	DET
fnp-5809	190	34	most	most	ADV
fnp-5809	190	35	advanced	advanced	ADJ
fnp-5809	190	36	studies	study	NOUN
fnp-5809	190	37	for	for	ADP
fnp-5809	190	38	residual	residual	ADJ
fnp-5809	190	39	or	or	CCONJ
fnp-5809	190	40	recurrent	recurrent	ADJ
fnp-5809	190	41	cns	cns	NOUN
fnp-5809	190	42	who	who	PRON
fnp-5809	190	43	grade	grade	VERB
fnp-5809	190	44	2	2	NUM
fnp-5809	190	45	glioma	glioma	NOUN
fnp-5809	190	46	comprising	comprise	VERB
fnp-5809	190	47	331	331	NUM
fnp-5809	190	48	patients	patient	NOUN
fnp-5809	190	49	in	in	ADP
fnp-5809	190	50	total	total	ADJ
fnp-5809	190	51	[	[	X
fnp-5809	190	52	mellinghoff	mellinghoff	X
fnp-5809	190	53	et	et	PROPN
fnp-5809	190	54	al	al	PROPN
fnp-5809	190	55	.	.	PROPN
fnp-5809	190	56	,	,	PUNCT
fnp-5809	190	57	2023	2023	NUM
fnp-5809	190	58	]	]	PUNCT
fnp-5809	190	59	.	.	PUNCT
fnp-5809	191	1	the	the	DET
fnp-5809	191	2	patients	patient	NOUN
fnp-5809	191	3	orally	orally	ADV
fnp-5809	191	4	received	receive	VERB
fnp-5809	191	5	vorasidenib	vorasidenib	NOUN
fnp-5809	191	6	or	or	CCONJ
fnp-5809	191	7	placebo	placebo	NOUN
fnp-5809	191	8	daily	daily	ADV
fnp-5809	191	9	until	until	ADP
fnp-5809	191	10	disease	disease	NOUN
fnp-5809	191	11	progression	progression	NOUN
fnp-5809	191	12	or	or	CCONJ
fnp-5809	191	13	toxic	toxic	ADJ
fnp-5809	191	14	treatment	treatment	NOUN
fnp-5809	191	15	side	side	NOUN
fnp-5809	191	16	effects	effect	NOUN
fnp-5809	191	17	occurred	occur	VERB
fnp-5809	191	18	.	.	PUNCT
fnp-5809	192	1	vorasidenib	vorasidenib	PROPN
fnp-5809	192	2	treatment	treatment	NOUN
fnp-5809	192	3	was	be	AUX
fnp-5809	192	4	mainly	mainly	ADV
fnp-5809	192	5	associated	associate	VERB
fnp-5809	192	6	with	with	ADP
fnp-5809	192	7	low	low	ADJ
fnp-5809	192	8	-	-	PUNCT
fnp-5809	192	9	grade	grade	NOUN
fnp-5809	192	10	toxic	toxic	ADJ
fnp-5809	192	11	side	side	NOUN
fnp-5809	192	12	effects	effect	NOUN
fnp-5809	192	13	;	;	PUNCT
fnp-5809	192	14	however	however	SCONJ
fnp-5809	192	15	grade	grade	NOUN
fnp-5809	192	16	3	3	NUM
fnp-5809	192	17	or	or	CCONJ
fnp-5809	192	18	higher	high	ADJ
fnp-5809	192	19	side	side	NOUN
fnp-5809	192	20	effects	effect	NOUN
fnp-5809	192	21	were	be	AUX
fnp-5809	192	22	observed	observe	VERB
fnp-5809	192	23	in	in	ADP
fnp-5809	192	24	22.8	22.8	NUM
fnp-5809	192	25	 	 	SPACE
fnp-5809	192	26	%	%	NOUN
fnp-5809	192	27	of	of	ADP
fnp-5809	192	28	the	the	DET
fnp-5809	192	29	patients	patient	NOUN
fnp-5809	192	30	in	in	ADP
fnp-5809	192	31	the	the	DET
fnp-5809	192	32	vorasidenib	vorasidenib	NOUN
fnp-5809	192	33	as	as	SCONJ
fnp-5809	192	34	compared	compare	VERB
fnp-5809	192	35	to	to	ADP
fnp-5809	192	36	13.5	13.5	NUM
fnp-5809	192	37	 	 	SPACE
fnp-5809	192	38	%	%	NOUN
fnp-5809	192	39	in	in	ADP
fnp-5809	192	40	the	the	DET
fnp-5809	192	41	placebo	placebo	NOUN
fnp-5809	192	42	control	control	NOUN
fnp-5809	192	43	group	group	NOUN
fnp-5809	192	44	.	.	PUNCT
fnp-5809	193	1	of	of	ADP
fnp-5809	193	2	note	note	NOUN
fnp-5809	193	3	,	,	PUNCT
fnp-5809	193	4	only	only	ADV
fnp-5809	193	5	1.8	1.8	NUM
fnp-5809	193	6	 	 	SPACE
fnp-5809	193	7	%	%	NOUN
fnp-5809	193	8	of	of	ADP
fnp-5809	193	9	the	the	DET
fnp-5809	193	10	patients	patient	NOUN
fnp-5809	193	11	treated	treat	VERB
fnp-5809	193	12	with	with	ADP
fnp-5809	193	13	vorasidenib	vorasidenib	NOUN
fnp-5809	193	14	showed	show	VERB
fnp-5809	193	15	serious	serious	ADJ
fnp-5809	193	16	side	side	NOUN
fnp-5809	193	17	effects	effect	NOUN
fnp-5809	193	18	,	,	PUNCT
fnp-5809	193	19	therefore	therefore	ADV
fnp-5809	193	20	showing	show	VERB
fnp-5809	193	21	a	a	DET
fnp-5809	193	22	clinically	clinically	ADV
fnp-5809	193	23	acceptable	acceptable	ADJ
fnp-5809	193	24	safety	safety	NOUN
fnp-5809	193	25	profile	profile	NOUN
fnp-5809	193	26	.	.	PUNCT
fnp-5809	194	1	the	the	DET
fnp-5809	194	2	median	median	ADJ
fnp-5809	194	3	progression	progression	NOUN
fnp-5809	194	4	-	-	PUNCT
fnp-5809	194	5	free	free	ADJ
fnp-5809	194	6	survival	survival	NOUN
fnp-5809	194	7	was	be	AUX
fnp-5809	194	8	significantly	significantly	ADV
fnp-5809	194	9	improved	improve	VERB
fnp-5809	194	10	upon	upon	SCONJ
fnp-5809	194	11	vorasidenib	vorasidenib	NOUN
fnp-5809	194	12	treatment	treatment	NOUN
fnp-5809	194	13	,	,	PUNCT
fnp-5809	194	14	reaching	reach	VERB
fnp-5809	194	15	27.7	27.7	NUM
fnp-5809	194	16	months	month	NOUN
fnp-5809	194	17	compared	compare	VERB
fnp-5809	194	18	to	to	ADP
fnp-5809	194	19	only	only	ADV
fnp-5809	194	20	11.1	11.1	NUM
fnp-5809	194	21	months	month	NOUN
fnp-5809	194	22	in	in	ADP
fnp-5809	194	23	the	the	DET
fnp-5809	194	24	placebo	placebo	NOUN
fnp-5809	194	25	control	control	NOUN
fnp-5809	194	26	group	group	NOUN
fnp-5809	194	27	.	.	PUNCT
fnp-5809	195	1	furthermore	furthermore	ADV
fnp-5809	195	2	,	,	PUNCT
fnp-5809	195	3	time	time	NOUN
fnp-5809	195	4	to	to	ADP
fnp-5809	195	5	next	next	ADJ
fnp-5809	195	6	follow	follow	VERB
fnp-5809	195	7	-	-	PUNCT
fnp-5809	195	8	up	up	ADP
fnp-5809	195	9	treatment	treatment	NOUN
fnp-5809	195	10	was	be	AUX
fnp-5809	195	11	significantly	significantly	ADV
fnp-5809	195	12	longer	long	ADJ
fnp-5809	195	13	in	in	ADP
fnp-5809	195	14	the	the	DET
fnp-5809	195	15	vorasidenib	vorasidenib	NOUN
fnp-5809	195	16	treated	treat	VERB
fnp-5809	195	17	patients	patient	NOUN
fnp-5809	195	18	for	for	ADP
fnp-5809	195	19	which	which	PRON
fnp-5809	195	20	the	the	DET
fnp-5809	195	21	median	median	NOUN
fnp-5809	195	22	had	have	AUX
fnp-5809	195	23	not	not	PART
fnp-5809	195	24	been	be	AUX
fnp-5809	195	25	reached	reach	VERB
fnp-5809	195	26	by	by	ADP
fnp-5809	195	27	the	the	DET
fnp-5809	195	28	time	time	NOUN
fnp-5809	195	29	of	of	ADP
fnp-5809	195	30	publication	publication	NOUN
fnp-5809	195	31	of	of	ADP
fnp-5809	195	32	the	the	DET
fnp-5809	195	33	study	study	NOUN
fnp-5809	195	34	while	while	SCONJ
fnp-5809	195	35	the	the	DET
fnp-5809	195	36	placebo	placebo	NOUN
fnp-5809	195	37	group	group	NOUN
fnp-5809	195	38	reached	reach	VERB
fnp-5809	195	39	the	the	DET
fnp-5809	195	40	median	median	NOUN
fnp-5809	195	41	at	at	ADP
fnp-5809	195	42	17.8	17.8	NUM
fnp-5809	195	43	months	month	NOUN
fnp-5809	195	44	.	.	PUNCT
fnp-5809	196	1	this	this	DET
fnp-5809	196	2	study	study	NOUN
fnp-5809	196	3	is	be	AUX
fnp-5809	196	4	another	another	DET
fnp-5809	196	5	milestone	milestone	NOUN
fnp-5809	196	6	on	on	ADP
fnp-5809	196	7	the	the	DET
fnp-5809	196	8	way	way	NOUN
fnp-5809	196	9	to	to	ADP
fnp-5809	196	10	more	more	ADV
fnp-5809	196	11	specific	specific	ADJ
fnp-5809	196	12	,	,	PUNCT
fnp-5809	196	13	efficacious	efficacious	ADJ
fnp-5809	196	14	and	and	CCONJ
fnp-5809	196	15	safe	safe	ADJ
fnp-5809	196	16	brain	brain	NOUN
fnp-5809	196	17	tumor	tumor	NOUN
fnp-5809	196	18	treatments	treatment	NOUN
fnp-5809	196	19	.	.	PUNCT
fnp-5809	197	1	the	the	DET
fnp-5809	197	2	us	us	PROPN
fnp-5809	197	3	food	food	NOUN
fnp-5809	197	4	and	and	CCONJ
fnp-5809	197	5	drug	drug	NOUN
fnp-5809	197	6	administration	administration	NOUN
fnp-5809	197	7	has	have	AUX
fnp-5809	197	8	now	now	ADV
fnp-5809	197	9	approved	approve	VERB
fnp-5809	197	10	vorasidenib	vorasidenib	NOUN
fnp-5809	197	11	as	as	ADP
fnp-5809	197	12	a	a	DET
fnp-5809	197	13	systemic	systemic	ADJ
fnp-5809	197	14	therapy	therapy	NOUN
fnp-5809	197	15	for	for	ADP
fnp-5809	197	16	patients	patient	NOUN
fnp-5809	197	17	with	with	ADP
fnp-5809	197	18	grade	grade	NOUN
fnp-5809	197	19	2	2	NUM
fnp-5809	197	20	astrocytoma	astrocytoma	NOUN
fnp-5809	197	21	or	or	CCONJ
fnp-5809	197	22	oligodendroglioma	oligodendroglioma	VERB
fnp-5809	197	23	with	with	ADP
fnp-5809	197	24	a	a	DET
fnp-5809	197	25	susceptible	susceptible	ADJ
fnp-5809	197	26	idh1	idh1	NOUN
fnp-5809	197	27	or	or	CCONJ
fnp-5809	197	28	idh2	idh2	PROPN
fnp-5809	197	29	mutation	mutation	PROPN
fnp-5809	197	30	,	,	PUNCT
fnp-5809	197	31	based	base	VERB
fnp-5809	197	32	largely	largely	ADV
fnp-5809	197	33	on	on	ADP
fnp-5809	197	34	the	the	DET
fnp-5809	197	35	result	result	NOUN
fnp-5809	197	36	of	of	ADP
fnp-5809	197	37	this	this	DET
fnp-5809	197	38	study	study	NOUN
fnp-5809	197	39	(	(	PUNCT
fnp-5809	197	40	see	see	VERB
fnp-5809	197	41	https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-vorasidenib-grade-2-astrocytoma-or-oligodendroglioma-susceptible-idh1-or-idh2-mutation	https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-vorasidenib-grade-2-astrocytoma-or-oligodendroglioma-susceptible-idh1-or-idh2-mutation	NOUN
fnp-5809	197	42	)	)	PUNCT
fnp-5809	197	43	.	.	PUNCT
fnp-5809	198	1	discussion	discussion	NOUN
fnp-5809	198	2	in	in	ADP
fnp-5809	198	3	2023	2023	NUM
fnp-5809	198	4	,	,	PUNCT
fnp-5809	198	5	several	several	ADJ
fnp-5809	198	6	novel	novel	ADJ
fnp-5809	198	7	pathogenic	pathogenic	ADJ
fnp-5809	198	8	mechanisms	mechanism	NOUN
fnp-5809	198	9	were	be	AUX
fnp-5809	198	10	published	publish	VERB
fnp-5809	198	11	that	that	PRON
fnp-5809	198	12	might	might	AUX
fnp-5809	198	13	serve	serve	VERB
fnp-5809	198	14	as	as	ADP
fnp-5809	198	15	potential	potential	ADJ
fnp-5809	198	16	targets	target	NOUN
fnp-5809	198	17	for	for	ADP
fnp-5809	198	18	oncological	oncological	ADJ
fnp-5809	198	19	treatment	treatment	NOUN
fnp-5809	198	20	approaches	approach	NOUN
fnp-5809	198	21	in	in	ADP
fnp-5809	198	22	the	the	DET
fnp-5809	198	23	future	future	NOUN
fnp-5809	198	24	.	.	PUNCT
fnp-5809	199	1	however	however	ADV
fnp-5809	199	2	,	,	PUNCT
fnp-5809	199	3	it	it	PRON
fnp-5809	199	4	still	still	ADV
fnp-5809	199	5	remains	remain	VERB
fnp-5809	199	6	to	to	PART
fnp-5809	199	7	be	be	AUX
fnp-5809	199	8	determined	determine	VERB
fnp-5809	199	9	if	if	SCONJ
fnp-5809	199	10	those	those	DET
fnp-5809	199	11	mechanisms	mechanism	NOUN
fnp-5809	199	12	can	can	AUX
fnp-5809	199	13	be	be	AUX
fnp-5809	199	14	targeted	target	VERB
fnp-5809	199	15	with	with	ADP
fnp-5809	199	16	high	high	ADJ
fnp-5809	199	17	specificity	specificity	NOUN
fnp-5809	199	18	without	without	ADP
fnp-5809	199	19	having	have	VERB
fnp-5809	199	20	negative	negative	ADJ
fnp-5809	199	21	side	side	ADJ
fnp-5809	199	22	effects	effect	NOUN
fnp-5809	199	23	.	.	PUNCT
fnp-5809	200	1	for	for	ADP
fnp-5809	200	2	example	example	NOUN
fnp-5809	200	3	,	,	PUNCT
fnp-5809	200	4	spontaneous	spontaneous	ADJ
fnp-5809	200	5	ca2	ca2	PROPN
fnp-5809	200	6	+	+	PROPN
fnp-5809	200	7	oscillations	oscillation	NOUN
fnp-5809	200	8	are	be	AUX
fnp-5809	200	9	key	key	ADJ
fnp-5809	200	10	in	in	ADP
fnp-5809	200	11	the	the	DET
fnp-5809	200	12	modulation	modulation	NOUN
fnp-5809	200	13	of	of	ADP
fnp-5809	200	14	glioneuronal	glioneuronal	ADJ
fnp-5809	200	15	synaptic	synaptic	ADJ
fnp-5809	200	16	information	information	NOUN
fnp-5809	201	1	[	[	X
fnp-5809	201	2	goenaga	goenaga	NOUN
fnp-5809	201	3	et	et	PROPN
fnp-5809	201	4	al	al	PROPN
fnp-5809	201	5	.	.	PROPN
fnp-5809	201	6	,	,	PUNCT
fnp-5809	201	7	2023	2023	NUM
fnp-5809	201	8	]	]	PUNCT
fnp-5809	201	9	.	.	PUNCT
fnp-5809	202	1	therefore	therefore	ADV
fnp-5809	202	2	,	,	PUNCT
fnp-5809	202	3	it	it	PRON
fnp-5809	202	4	is	be	AUX
fnp-5809	202	5	unclear	unclear	ADJ
fnp-5809	202	6	if	if	SCONJ
fnp-5809	202	7	rhythmic	rhythmic	ADJ
fnp-5809	202	8	ca2	ca2	PROPN
fnp-5809	202	9	+	+	PROPN
fnp-5809	202	10	oscillations	oscillation	NOUN
fnp-5809	202	11	that	that	PRON
fnp-5809	202	12	activate	activate	VERB
fnp-5809	202	13	frequency	frequency	NOUN
fnp-5809	202	14	-	-	PUNCT
fnp-5809	202	15	dependent	dependent	ADJ
fnp-5809	202	16	mapk	mapk	NOUN
fnp-5809	202	17	and	and	CCONJ
fnp-5809	202	18	nfkb	nfkb	PROPN
fnp-5809	202	19	pathway	pathway	NOUN
fnp-5809	202	20	in	in	ADP
fnp-5809	202	21	the	the	DET
fnp-5809	202	22	context	context	NOUN
fnp-5809	202	23	of	of	ADP
fnp-5809	202	24	brain	brain	NOUN
fnp-5809	202	25	tumors	tumor	NOUN
fnp-5809	202	26	may	may	AUX
fnp-5809	202	27	be	be	AUX
fnp-5809	202	28	selectively	selectively	ADV
fnp-5809	202	29	targeted	target	VERB
fnp-5809	202	30	without	without	ADP
fnp-5809	202	31	negatively	negatively	ADV
fnp-5809	202	32	impacting	impact	VERB
fnp-5809	202	33	the	the	DET
fnp-5809	202	34	normal	normal	ADJ
fnp-5809	202	35	neurophysiological	neurophysiological	ADJ
fnp-5809	202	36	circuits	circuit	NOUN
fnp-5809	202	37	[	[	X
fnp-5809	202	38	hausmann	hausmann	PROPN
fnp-5809	202	39	et	et	PROPN
fnp-5809	202	40	al	al	PROPN
fnp-5809	202	41	.	.	PROPN
fnp-5809	202	42	,	,	PUNCT
fnp-5809	202	43	2023	2023	NUM
fnp-5809	202	44	]	]	PUNCT
fnp-5809	202	45	.	.	PUNCT
fnp-5809	203	1	to	to	PART
fnp-5809	203	2	which	which	DET
fnp-5809	203	3	degree	degree	NOUN
fnp-5809	203	4	a	a	DET
fnp-5809	203	5	potential	potential	ADJ
fnp-5809	203	6	inhibition	inhibition	NOUN
fnp-5809	203	7	of	of	ADP
fnp-5809	203	8	gap43	gap43	NOUN
fnp-5809	203	9	-	-	PUNCT
fnp-5809	203	10	dependent	dependent	ADJ
fnp-5809	203	11	transfer	transfer	NOUN
fnp-5809	203	12	of	of	ADP
fnp-5809	203	13	mitochondria	mitochondria	NOUN
fnp-5809	203	14	from	from	ADP
fnp-5809	203	15	normal	normal	ADJ
fnp-5809	203	16	astrocytes	astrocyte	NOUN
fnp-5809	203	17	to	to	ADP
fnp-5809	203	18	glioma	glioma	NOUN
fnp-5809	203	19	cells	cell	NOUN
fnp-5809	203	20	may	may	AUX
fnp-5809	203	21	slow	slow	VERB
fnp-5809	203	22	down	down	ADP
fnp-5809	203	23	tumor	tumor	NOUN
fnp-5809	203	24	growth	growth	NOUN
fnp-5809	203	25	also	also	ADV
fnp-5809	203	26	in	in	ADP
fnp-5809	203	27	the	the	DET
fnp-5809	203	28	human	human	ADJ
fnp-5809	203	29	context	context	NOUN
fnp-5809	203	30	has	have	VERB
fnp-5809	203	31	to	to	PART
fnp-5809	203	32	be	be	AUX
fnp-5809	203	33	clarified	clarify	VERB
fnp-5809	204	1	[	[	PUNCT
fnp-5809	204	2	watson	watson	PROPN
fnp-5809	204	3	et	et	PROPN
fnp-5809	204	4	al	al	PROPN
fnp-5809	204	5	.	.	PROPN
fnp-5809	204	6	,	,	PUNCT
fnp-5809	204	7	2023	2023	NUM
fnp-5809	204	8	]	]	PUNCT
fnp-5809	204	9	.	.	PUNCT
fnp-5809	205	1	although	although	SCONJ
fnp-5809	205	2	it	it	PRON
fnp-5809	205	3	seems	seem	VERB
fnp-5809	205	4	obvious	obvious	ADJ
fnp-5809	205	5	that	that	SCONJ
fnp-5809	205	6	fresh	fresh	ADJ
fnp-5809	205	7	and	and	CCONJ
fnp-5809	205	8	healthy	healthy	ADJ
fnp-5809	205	9	mitochondria	mitochondria	NOUN
fnp-5809	205	10	transferred	transfer	VERB
fnp-5809	205	11	to	to	ADP
fnp-5809	205	12	potentially	potentially	ADV
fnp-5809	205	13	exhausted	exhaust	VERB
fnp-5809	205	14	glioma	glioma	NOUN
fnp-5809	205	15	cells	cell	NOUN
fnp-5809	205	16	may	may	AUX
fnp-5809	205	17	serve	serve	VERB
fnp-5809	205	18	as	as	ADP
fnp-5809	205	19	a	a	DET
fnp-5809	205	20	powerhouse	powerhouse	NOUN
fnp-5809	205	21	,	,	PUNCT
fnp-5809	205	22	a	a	DET
fnp-5809	205	23	high	high	ADJ
fnp-5809	205	24	metabolic	metabolic	NOUN
fnp-5809	205	25	plasticity	plasticity	NOUN
fnp-5809	205	26	has	have	AUX
fnp-5809	205	27	been	be	AUX
fnp-5809	205	28	reported	report	VERB
fnp-5809	205	29	for	for	ADP
fnp-5809	205	30	glioma	glioma	NOUN
fnp-5809	205	31	cells	cell	NOUN
fnp-5809	205	32	allowing	allow	VERB
fnp-5809	205	33	for	for	ADP
fnp-5809	205	34	sustainable	sustainable	ADJ
fnp-5809	205	35	tumor	tumor	NOUN
fnp-5809	205	36	propagation	propagation	NOUN
fnp-5809	205	37	via	via	ADP
fnp-5809	205	38	glycolytic	glycolytic	ADJ
fnp-5809	205	39	energy	energy	NOUN
fnp-5809	205	40	production	production	NOUN
fnp-5809	205	41	if	if	SCONJ
fnp-5809	205	42	mitochondrial	mitochondrial	ADJ
fnp-5809	205	43	-	-	PUNCT
fnp-5809	205	44	type	type	NOUN
fnp-5809	205	45	energy	energy	NOUN
fnp-5809	205	46	supply	supply	NOUN
fnp-5809	205	47	is	be	AUX
fnp-5809	205	48	impaired	impair	VERB
fnp-5809	205	49	[	[	X
fnp-5809	205	50	shibao	shibao	X
fnp-5809	205	51	et	et	PROPN
fnp-5809	205	52	al	al	PROPN
fnp-5809	205	53	.	.	PROPN
fnp-5809	205	54	,	,	PUNCT
fnp-5809	205	55	2018	2018	NUM
fnp-5809	205	56	]	]	PUNCT
fnp-5809	205	57	.	.	PUNCT
fnp-5809	206	1	this	this	DET
fnp-5809	206	2	glioma	glioma	NOUN
fnp-5809	206	3	cell	cell	NOUN
fnp-5809	206	4	feature	feature	NOUN
fnp-5809	206	5	may	may	AUX
fnp-5809	206	6	limit	limit	VERB
fnp-5809	206	7	a	a	DET
fnp-5809	206	8	treatment	treatment	NOUN
fnp-5809	206	9	approach	approach	NOUN
fnp-5809	206	10	targeting	target	VERB
fnp-5809	206	11	the	the	DET
fnp-5809	206	12	intercellular	intercellular	ADJ
fnp-5809	206	13	transfer	transfer	NOUN
fnp-5809	206	14	of	of	ADP
fnp-5809	206	15	mitochondria	mitochondria	NOUN
fnp-5809	206	16	between	between	ADP
fnp-5809	206	17	normal	normal	ADJ
fnp-5809	206	18	and	and	CCONJ
fnp-5809	206	19	neoplastic	neoplastic	ADJ
fnp-5809	206	20	glial	glial	ADJ
fnp-5809	206	21	cells	cell	NOUN
fnp-5809	206	22	.	.	PUNCT
fnp-5809	207	1	the	the	DET
fnp-5809	207	2	findings	finding	NOUN
fnp-5809	207	3	regarding	regard	VERB
fnp-5809	207	4	the	the	DET
fnp-5809	207	5	involvement	involvement	NOUN
fnp-5809	207	6	of	of	ADP
fnp-5809	207	7	matrix	matrix	NOUN
fnp-5809	207	8	-	-	PUNCT
fnp-5809	207	9	metalloprotease	metalloprotease	NOUN
fnp-5809	207	10	(	(	PUNCT
fnp-5809	207	11	mmp	mmp	PROPN
fnp-5809	207	12	)	)	PUNCT
fnp-5809	207	13	in	in	ADP
fnp-5809	207	14	the	the	DET
fnp-5809	207	15	process	process	NOUN
fnp-5809	207	16	of	of	ADP
fnp-5809	207	17	brain	brain	NOUN
fnp-5809	207	18	metastasis	metastasis	NOUN
fnp-5809	207	19	formation	formation	NOUN
fnp-5809	207	20	may	may	AUX
fnp-5809	207	21	serve	serve	VERB
fnp-5809	207	22	as	as	ADP
fnp-5809	207	23	another	another	DET
fnp-5809	207	24	promising	promising	ADJ
fnp-5809	207	25	therapeutic	therapeutic	ADJ
fnp-5809	207	26	target	target	NOUN
fnp-5809	207	27	in	in	ADP
fnp-5809	207	28	the	the	DET
fnp-5809	207	29	prevention	prevention	NOUN
fnp-5809	207	30	and	and	CCONJ
fnp-5809	207	31	treatment	treatment	NOUN
fnp-5809	207	32	of	of	ADP
fnp-5809	207	33	brain	brain	NOUN
fnp-5809	207	34	metastasis	metastasis	NOUN
fnp-5809	207	35	,	,	PUNCT
fnp-5809	207	36	especially	especially	ADV
fnp-5809	207	37	as	as	SCONJ
fnp-5809	207	38	several	several	ADJ
fnp-5809	207	39	synthetic	synthetic	ADJ
fnp-5809	207	40	mmp	mmp	PROPN
fnp-5809	207	41	inhibitors	inhibitor	NOUN
fnp-5809	207	42	have	have	AUX
fnp-5809	207	43	been	be	AUX
fnp-5809	207	44	produced	produce	VERB
fnp-5809	208	1	[	[	PUNCT
fnp-5809	208	2	karreman	karreman	NOUN
fnp-5809	208	3	et	et	PROPN
fnp-5809	208	4	al	al	PROPN
fnp-5809	208	5	.	.	PROPN
fnp-5809	208	6	,	,	PUNCT
fnp-5809	208	7	2023	2023	NUM
fnp-5809	208	8	]	]	PUNCT
fnp-5809	208	9	.	.	PUNCT
fnp-5809	209	1	unfortunately	unfortunately	ADV
fnp-5809	209	2	,	,	PUNCT
fnp-5809	209	3	to	to	ADP
fnp-5809	209	4	date	date	NOUN
fnp-5809	209	5	,	,	PUNCT
fnp-5809	209	6	many	many	ADJ
fnp-5809	209	7	oncological	oncological	ADJ
fnp-5809	209	8	trials	trial	NOUN
fnp-5809	209	9	applying	apply	VERB
fnp-5809	209	10	mmp	mmp	PROPN
fnp-5809	209	11	inhibitors	inhibitor	NOUN
fnp-5809	209	12	failed	fail	VERB
fnp-5809	209	13	because	because	SCONJ
fnp-5809	209	14	of	of	ADP
fnp-5809	209	15	either	either	DET
fnp-5809	209	16	lack	lack	NOUN
fnp-5809	209	17	of	of	ADP
fnp-5809	209	18	efficacy	efficacy	NOUN
fnp-5809	209	19	or	or	CCONJ
fnp-5809	209	20	severe	severe	ADJ
fnp-5809	209	21	adverse	adverse	ADJ
fnp-5809	209	22	side	side	NOUN
fnp-5809	209	23	effects	effect	NOUN
fnp-5809	209	24	[	[	X
fnp-5809	209	25	lopez	lopez	NOUN
fnp-5809	209	26	-	-	PUNCT
fnp-5809	209	27	navarro	navarro	PROPN
fnp-5809	209	28	and	and	CCONJ
fnp-5809	209	29	gutierrez	gutierrez	PROPN
fnp-5809	209	30	,	,	PUNCT
fnp-5809	209	31	2022	2022	NUM
fnp-5809	209	32	]	]	PUNCT
fnp-5809	209	33	.	.	PUNCT
fnp-5809	210	1	finally	finally	ADV
fnp-5809	210	2	,	,	PUNCT
fnp-5809	210	3	the	the	DET
fnp-5809	210	4	tumor	tumor	NOUN
fnp-5809	210	5	-	-	PUNCT
fnp-5809	210	6	suppressive	suppressive	ADJ
fnp-5809	210	7	effects	effect	NOUN
fnp-5809	210	8	of	of	ADP
fnp-5809	210	9	microglia	microglia	ADJ
fnp-5809	210	10	cells	cell	NOUN
fnp-5809	210	11	demonstrated	demonstrate	VERB
fnp-5809	210	12	in	in	ADP
fnp-5809	210	13	the	the	DET
fnp-5809	210	14	context	context	NOUN
fnp-5809	210	15	of	of	ADP
fnp-5809	210	16	brain	brain	NOUN
fnp-5809	210	17	metastasis	metastasis	NOUN
fnp-5809	210	18	formation	formation	NOUN
fnp-5809	210	19	need	need	VERB
fnp-5809	210	20	a	a	DET
fnp-5809	210	21	careful	careful	ADJ
fnp-5809	210	22	reassessment	reassessment	NOUN
fnp-5809	210	23	in	in	ADP
fnp-5809	210	24	humans	human	NOUN
fnp-5809	210	25	as	as	ADP
fnp-5809	210	26	to	to	ADP
fnp-5809	210	27	date	date	NOUN
fnp-5809	210	28	still	still	ADV
fnp-5809	210	29	many	many	ADJ
fnp-5809	210	30	studies	study	NOUN
fnp-5809	210	31	claim	claim	VERB
fnp-5809	210	32	a	a	DET
fnp-5809	210	33	promoting	promote	VERB
fnp-5809	210	34	microglial	microglial	ADJ
fnp-5809	210	35	effect	effect	NOUN
fnp-5809	210	36	for	for	ADP
fnp-5809	210	37	brain	brain	NOUN
fnp-5809	210	38	tumor	tumor	NOUN
fnp-5809	210	39	formation	formation	NOUN
fnp-5809	211	1	[	[	X
fnp-5809	211	2	evans	evans	PROPN
fnp-5809	211	3	et	et	PROPN
fnp-5809	211	4	al	al	PROPN
fnp-5809	211	5	.	.	PROPN
fnp-5809	211	6	,	,	PUNCT
fnp-5809	211	7	2023	2023	NUM
fnp-5809	211	8	]	]	PUNCT
fnp-5809	211	9	.	.	PUNCT
fnp-5809	212	1	as	as	SCONJ
fnp-5809	212	2	previous	previous	ADJ
fnp-5809	212	3	studies	study	NOUN
fnp-5809	212	4	in	in	ADP
fnp-5809	212	5	glioma	glioma	NOUN
fnp-5809	212	6	have	have	AUX
fnp-5809	212	7	shown	show	VERB
fnp-5809	212	8	,	,	PUNCT
fnp-5809	212	9	the	the	DET
fnp-5809	212	10	role	role	NOUN
fnp-5809	212	11	of	of	ADP
fnp-5809	212	12	microglial	microglial	ADJ
fnp-5809	212	13	cells	cell	NOUN
fnp-5809	212	14	in	in	ADP
fnp-5809	212	15	brain	brain	NOUN
fnp-5809	212	16	tumors	tumor	NOUN
fnp-5809	212	17	is	be	AUX
fnp-5809	212	18	probably	probably	ADV
fnp-5809	212	19	less	less	ADV
fnp-5809	212	20	black	black	ADJ
fnp-5809	212	21	and	and	CCONJ
fnp-5809	212	22	white	white	ADJ
fnp-5809	212	23	and	and	CCONJ
fnp-5809	212	24	rather	rather	ADV
fnp-5809	212	25	reflects	reflect	VERB
fnp-5809	212	26	a	a	DET
fnp-5809	212	27	high	high	ADJ
fnp-5809	212	28	cellular	cellular	ADJ
fnp-5809	212	29	plasticity	plasticity	NOUN
fnp-5809	212	30	that	that	PRON
fnp-5809	212	31	is	be	AUX
fnp-5809	212	32	related	relate	VERB
fnp-5809	212	33	to	to	ADP
fnp-5809	212	34	intratumoral	intratumoral	ADJ
fnp-5809	212	35	microenvironmental	microenvironmental	ADJ
fnp-5809	212	36	changes	change	NOUN
fnp-5809	212	37	resulting	result	VERB
fnp-5809	212	38	in	in	ADP
fnp-5809	212	39	both	both	DET
fnp-5809	212	40	classic	classic	ADJ
fnp-5809	212	41	proand	proand	NOUN
fnp-5809	212	42	anti	anti	ADJ
fnp-5809	212	43	-	-	ADJ
fnp-5809	212	44	tumoral	tumoral	ADJ
fnp-5809	212	45	features	feature	NOUN
fnp-5809	212	46	within	within	ADP
fnp-5809	212	47	the	the	DET
fnp-5809	212	48	same	same	ADJ
fnp-5809	212	49	tumor	tumor	NOUN
fnp-5809	213	1	[	[	X
fnp-5809	213	2	zeiner	zeiner	NOUN
fnp-5809	213	3	et	et	PROPN
fnp-5809	213	4	al	al	PROPN
fnp-5809	213	5	.	.	PROPN
fnp-5809	213	6	,	,	PUNCT
fnp-5809	213	7	2019	2019	NUM
fnp-5809	213	8	]	]	PUNCT
fnp-5809	213	9	.	.	PUNCT
fnp-5809	214	1	in	in	ADP
fnp-5809	214	2	summary	summary	NOUN
fnp-5809	214	3	,	,	PUNCT
fnp-5809	214	4	although	although	SCONJ
fnp-5809	214	5	the	the	DET
fnp-5809	214	6	aforementioned	aforementioned	ADJ
fnp-5809	214	7	studies	study	NOUN
fnp-5809	214	8	provide	provide	VERB
fnp-5809	214	9	fascinating	fascinating	ADJ
fnp-5809	214	10	findings	finding	NOUN
fnp-5809	214	11	about	about	ADP
fnp-5809	214	12	brain	brain	NOUN
fnp-5809	214	13	tumor	tumor	NOUN
fnp-5809	214	14	pathomechanisms	pathomechanism	NOUN
fnp-5809	214	15	,	,	PUNCT
fnp-5809	214	16	it	it	PRON
fnp-5809	214	17	seems	seem	VERB
fnp-5809	214	18	to	to	PART
fnp-5809	214	19	be	be	AUX
fnp-5809	214	20	too	too	ADV
fnp-5809	214	21	early	early	ADJ
fnp-5809	214	22	to	to	PART
fnp-5809	214	23	concretely	concretely	ADV
fnp-5809	214	24	judge	judge	VERB
fnp-5809	214	25	the	the	DET
fnp-5809	214	26	related	relate	VERB
fnp-5809	214	27	diagnostic	diagnostic	ADJ
fnp-5809	214	28	and	and	CCONJ
fnp-5809	214	29	,	,	PUNCT
fnp-5809	214	30	most	most	ADV
fnp-5809	214	31	importantly	importantly	ADV
fnp-5809	214	32	,	,	PUNCT
fnp-5809	214	33	therapeutic	therapeutic	ADJ
fnp-5809	214	34	potential	potential	NOUN
fnp-5809	214	35	.	.	PUNCT
fnp-5809	215	1	in	in	ADP
fnp-5809	215	2	contrast	contrast	NOUN
fnp-5809	215	3	,	,	PUNCT
fnp-5809	215	4	the	the	DET
fnp-5809	215	5	diagnostic	diagnostic	ADJ
fnp-5809	215	6	and	and	CCONJ
fnp-5809	215	7	prognostic	prognostic	ADJ
fnp-5809	215	8	potential	potential	NOUN
fnp-5809	215	9	for	for	ADP
fnp-5809	215	10	the	the	DET
fnp-5809	215	11	proposed	propose	VERB
fnp-5809	215	12	new	new	ADJ
fnp-5809	215	13	tumor	tumor	NOUN
fnp-5809	215	14	entities	entity	NOUN
fnp-5809	215	15	seem	seem	VERB
fnp-5809	215	16	to	to	PART
fnp-5809	215	17	be	be	AUX
fnp-5809	215	18	clear	clear	ADJ
fnp-5809	215	19	.	.	PUNCT
fnp-5809	216	1	for	for	ADP
fnp-5809	216	2	the	the	DET
fnp-5809	216	3	glioneuronal	glioneuronal	ADJ
fnp-5809	216	4	tumor	tumor	NOUN
fnp-5809	216	5	with	with	ADP
fnp-5809	216	6	atrx	atrx	PROPN
fnp-5809	216	7	alteration	alteration	NOUN
fnp-5809	216	8	,	,	PUNCT
fnp-5809	216	9	ntrk	ntrk	NOUN
fnp-5809	216	10	gene	gene	NOUN
fnp-5809	216	11	fusion	fusion	NOUN
fnp-5809	216	12	and	and	CCONJ
fnp-5809	216	13	anaplastic	anaplastic	ADJ
fnp-5809	216	14	features	feature	NOUN
fnp-5809	216	15	(	(	PUNCT
fnp-5809	216	16	gtaka	gtaka	NOUN
fnp-5809	216	17	)	)	PUNCT
fnp-5809	216	18	,	,	PUNCT
fnp-5809	216	19	the	the	DET
fnp-5809	216	20	detrimental	detrimental	ADJ
fnp-5809	216	21	clinical	clinical	ADJ
fnp-5809	216	22	course	course	NOUN
fnp-5809	216	23	that	that	PRON
fnp-5809	216	24	is	be	AUX
fnp-5809	216	25	rather	rather	ADV
fnp-5809	216	26	unusual	unusual	ADJ
fnp-5809	216	27	for	for	SCONJ
fnp-5809	216	28	many	many	ADJ
fnp-5809	216	29	glioneuronal	glioneuronal	ADJ
fnp-5809	216	30	tumors	tumor	NOUN
fnp-5809	216	31	has	have	VERB
fnp-5809	216	32	to	to	PART
fnp-5809	216	33	be	be	AUX
fnp-5809	216	34	stressed	stress	VERB
fnp-5809	216	35	[	[	X
fnp-5809	216	36	bogumil	bogumil	PROPN
fnp-5809	216	37	et	et	PROPN
fnp-5809	216	38	al	al	PROPN
fnp-5809	216	39	.	.	PROPN
fnp-5809	216	40	,	,	PUNCT
fnp-5809	216	41	2023	2023	NUM
fnp-5809	216	42	]	]	PUNCT
fnp-5809	216	43	.	.	PUNCT
fnp-5809	217	1	as	as	SCONJ
fnp-5809	217	2	gtaka	gtaka	PROPN
fnp-5809	217	3	could	could	AUX
fnp-5809	217	4	be	be	AUX
fnp-5809	217	5	unequivocally	unequivocally	ADV
fnp-5809	217	6	defined	define	VERB
fnp-5809	217	7	as	as	ADP
fnp-5809	217	8	a	a	DET
fnp-5809	217	9	new	new	ADJ
fnp-5809	217	10	class	class	NOUN
fnp-5809	217	11	using	use	VERB
fnp-5809	217	12	methylation	methylation	NOUN
fnp-5809	217	13	classification	classification	NOUN
fnp-5809	217	14	,	,	PUNCT
fnp-5809	217	15	its	its	PRON
fnp-5809	217	16	diagnosis	diagnosis	NOUN
fnp-5809	217	17	also	also	ADV
fnp-5809	217	18	seems	seem	VERB
fnp-5809	217	19	to	to	PART
fnp-5809	217	20	be	be	AUX
fnp-5809	217	21	straightforward	straightforward	ADJ
fnp-5809	217	22	.	.	PUNCT
fnp-5809	218	1	the	the	DET
fnp-5809	218	2	proposed	propose	VERB
fnp-5809	218	3	new	new	ADJ
fnp-5809	218	4	entity	entity	NOUN
fnp-5809	218	5	of	of	ADP
fnp-5809	218	6	“	"	PUNCT
fnp-5809	218	7	de	de	X
fnp-5809	218	8	novo	novo	NOUN
fnp-5809	218	9	replication	replication	NOUN
fnp-5809	218	10	repair	repair	NOUN
fnp-5809	218	11	deficient	deficient	ADJ
fnp-5809	218	12	glioblastoma	glioblastoma	NOUN
fnp-5809	218	13	,	,	PUNCT
fnp-5809	218	14	idh	idh	PROPN
fnp-5809	218	15	wildtype	wildtype	PROPN
fnp-5809	218	16	”	"	PUNCT
fnp-5809	218	17	harbors	harbor	VERB
fnp-5809	218	18	a	a	DET
fnp-5809	218	19	better	well	ADJ
fnp-5809	218	20	prognosis	prognosis	NOUN
fnp-5809	218	21	as	as	ADP
fnp-5809	218	22	compared	compare	VERB
fnp-5809	218	23	to	to	ADP
fnp-5809	218	24	other	other	ADJ
fnp-5809	218	25	glioblastoma	glioblastoma	NOUN
fnp-5809	218	26	variants	variant	NOUN
fnp-5809	219	1	[	[	X
fnp-5809	219	2	hadad	hadad	PROPN
fnp-5809	219	3	et	et	PROPN
fnp-5809	219	4	al	al	PROPN
fnp-5809	219	5	.	.	PROPN
fnp-5809	219	6	,	,	PUNCT
fnp-5809	219	7	2023	2023	NUM
fnp-5809	219	8	]	]	PUNCT
fnp-5809	219	9	,	,	PUNCT
fnp-5809	219	10	and	and	CCONJ
fnp-5809	219	11	may	may	AUX
fnp-5809	219	12	also	also	ADV
fnp-5809	219	13	profit	profit	VERB
fnp-5809	219	14	from	from	ADP
fnp-5809	219	15	checkpoint	checkpoint	NOUN
fnp-5809	219	16	inhibitors	inhibitor	NOUN
fnp-5809	219	17	.	.	PUNCT
fnp-5809	220	1	both	both	PRON
fnp-5809	220	2	diagnosis	diagnosis	NOUN
fnp-5809	220	3	and	and	CCONJ
fnp-5809	220	4	treatment	treatment	NOUN
fnp-5809	220	5	rely	rely	VERB
fnp-5809	220	6	on	on	ADP
fnp-5809	220	7	a	a	DET
fnp-5809	220	8	neuropathological	neuropathological	ADJ
fnp-5809	220	9	diagnostic	diagnostic	ADJ
fnp-5809	220	10	approach	approach	NOUN
fnp-5809	220	11	requiring	require	VERB
fnp-5809	220	12	mmr	mmr	PROPN
fnp-5809	220	13	and	and	CCONJ
fnp-5809	220	14	tmb	tmb	NOUN
fnp-5809	220	15	testing	testing	NOUN
fnp-5809	220	16	in	in	ADP
fnp-5809	220	17	diffuse	diffuse	ADJ
fnp-5809	220	18	high	high	ADJ
fnp-5809	220	19	-	-	PUNCT
fnp-5809	220	20	grade	grade	NOUN
fnp-5809	220	21	gliomas	glioma	NOUN
fnp-5809	220	22	:	:	PUNCT
fnp-5809	220	23	a	a	X
fnp-5809	220	24	)	)	PUNCT
fnp-5809	220	25	presenting	present	VERB
fnp-5809	220	26	in	in	ADP
fnp-5809	220	27	patients	patient	NOUN
fnp-5809	220	28	with	with	ADP
fnp-5809	220	29	a	a	DET
fnp-5809	220	30	younger	young	ADJ
fnp-5809	220	31	median	median	ADJ
fnp-5809	220	32	age	age	NOUN
fnp-5809	220	33	(	(	PUNCT
fnp-5809	220	34	50	50	NUM
fnp-5809	220	35	years	year	NOUN
fnp-5809	220	36	)	)	PUNCT
fnp-5809	220	37	as	as	SCONJ
fnp-5809	220	38	compared	compare	VERB
fnp-5809	220	39	to	to	ADP
fnp-5809	220	40	conventional	conventional	ADJ
fnp-5809	220	41	glioblastoma	glioblastoma	NOUN
fnp-5809	220	42	,	,	PUNCT
fnp-5809	220	43	b	b	NOUN
fnp-5809	220	44	)	)	PUNCT
fnp-5809	220	45	showing	show	VERB
fnp-5809	220	46	a	a	DET
fnp-5809	220	47	giant	giant	ADJ
fnp-5809	220	48	cell	cell	NOUN
fnp-5809	220	49	morphology	morphology	NOUN
fnp-5809	220	50	,	,	PUNCT
fnp-5809	220	51	and	and	CCONJ
fnp-5809	220	52	c	c	X
fnp-5809	220	53	)	)	PUNCT
fnp-5809	220	54	lacking	lack	VERB
fnp-5809	220	55	classic	classic	ADJ
fnp-5809	220	56	methylation	methylation	NOUN
fnp-5809	220	57	or	or	CCONJ
fnp-5809	220	58	mutational	mutational	ADJ
fnp-5809	220	59	features	feature	NOUN
fnp-5809	220	60	usually	usually	ADV
fnp-5809	220	61	observed	observe	VERB
fnp-5809	220	62	in	in	ADP
fnp-5809	220	63	conventional	conventional	ADJ
fnp-5809	220	64	glioblastoma	glioblastoma	NOUN
fnp-5809	220	65	(	(	PUNCT
fnp-5809	220	66	table	table	NOUN
fnp-5809	220	67	2	2	NUM
fnp-5809	220	68	)	)	PUNCT
fnp-5809	220	69	.	.	PUNCT
fnp-5809	221	1	the	the	DET
fnp-5809	221	2	diagnostics	diagnostic	NOUN
fnp-5809	221	3	of	of	ADP
fnp-5809	221	4	such	such	ADJ
fnp-5809	221	5	new	new	ADJ
fnp-5809	221	6	entities	entity	NOUN
fnp-5809	221	7	should	should	AUX
fnp-5809	221	8	also	also	ADV
fnp-5809	221	9	be	be	AUX
fnp-5809	221	10	taken	take	VERB
fnp-5809	221	11	into	into	ADP
fnp-5809	221	12	account	account	NOUN
fnp-5809	221	13	when	when	SCONJ
fnp-5809	221	14	developing	develop	VERB
fnp-5809	221	15	new	new	ADJ
fnp-5809	221	16	diagnostic	diagnostic	ADJ
fnp-5809	221	17	tools	tool	NOUN
fnp-5809	221	18	.	.	PUNCT
fnp-5809	222	1	the	the	DET
fnp-5809	222	2	ultra	ultra	ADJ
fnp-5809	222	3	-	-	ADJ
fnp-5809	222	4	fast	fast	ADJ
fnp-5809	222	5	,	,	PUNCT
fnp-5809	222	6	machine	machine	NOUN
fnp-5809	222	7	-	-	PUNCT
fnp-5809	222	8	learning	learning	NOUN
fnp-5809	222	9	based	base	VERB
fnp-5809	222	10	intraoperative	intraoperative	ADJ
fnp-5809	222	11	methylation	methylation	NOUN
fnp-5809	222	12	profiling	profiling	NOUN
fnp-5809	222	13	can	can	AUX
fnp-5809	222	14	be	be	AUX
fnp-5809	222	15	applied	apply	VERB
fnp-5809	222	16	without	without	ADP
fnp-5809	222	17	retraining	retrain	VERB
fnp-5809	222	18	but	but	CCONJ
fnp-5809	222	19	it	it	PRON
fnp-5809	222	20	is	be	AUX
fnp-5809	222	21	still	still	ADV
fnp-5809	222	22	based	base	VERB
fnp-5809	222	23	on	on	ADP
fnp-5809	222	24	methylation	methylation	NOUN
fnp-5809	222	25	data	datum	NOUN
fnp-5809	222	26	that	that	PRON
fnp-5809	222	27	has	have	AUX
fnp-5809	222	28	been	be	AUX
fnp-5809	222	29	published	publish	VERB
fnp-5809	222	30	a	a	DET
fnp-5809	222	31	few	few	ADJ
fnp-5809	222	32	years	year	NOUN
fnp-5809	222	33	ago	ago	ADV
fnp-5809	223	1	[	[	X
fnp-5809	223	2	vermeulen	vermeulen	NOUN
fnp-5809	223	3	et	et	PROPN
fnp-5809	223	4	al	al	PROPN
fnp-5809	223	5	.	.	PROPN
fnp-5809	223	6	,	,	PUNCT
fnp-5809	223	7	2023	2023	NUM
fnp-5809	223	8	]	]	PUNCT
fnp-5809	223	9	.	.	PUNCT
fnp-5809	224	1	it	it	PRON
fnp-5809	224	2	is	be	AUX
fnp-5809	224	3	therefore	therefore	ADV
fnp-5809	224	4	essential	essential	ADJ
fnp-5809	224	5	that	that	SCONJ
fnp-5809	224	6	the	the	DET
fnp-5809	224	7	neuropathological	neuropathological	ADJ
fnp-5809	224	8	community	community	NOUN
fnp-5809	224	9	aligns	align	VERB
fnp-5809	224	10	on	on	ADP
fnp-5809	224	11	joint	joint	ADJ
fnp-5809	224	12	diagnostic	diagnostic	ADJ
fnp-5809	224	13	standards	standard	NOUN
fnp-5809	224	14	,	,	PUNCT
fnp-5809	224	15	techniques	technique	NOUN
fnp-5809	224	16	and	and	CCONJ
fnp-5809	224	17	platforms	platform	NOUN
fnp-5809	224	18	so	so	SCONJ
fnp-5809	224	19	that	that	SCONJ
fnp-5809	224	20	molecular	molecular	ADJ
fnp-5809	224	21	profiling	profiling	NOUN
fnp-5809	224	22	can	can	AUX
fnp-5809	224	23	achieve	achieve	VERB
fnp-5809	224	24	similar	similar	ADJ
fnp-5809	224	25	results	result	NOUN
fnp-5809	224	26	world	world	NOUN
fnp-5809	224	27	-	-	PUNCT
fnp-5809	224	28	wide	wide	ADV
fnp-5809	224	29	.	.	PUNCT
fnp-5809	225	1	this	this	PRON
fnp-5809	225	2	is	be	AUX
fnp-5809	225	3	even	even	ADV
fnp-5809	225	4	more	more	ADV
fnp-5809	225	5	important	important	ADJ
fnp-5809	225	6	if	if	SCONJ
fnp-5809	225	7	different	different	ADJ
fnp-5809	225	8	layers	layer	NOUN
fnp-5809	225	9	of	of	ADP
fnp-5809	225	10	omics	omic	NOUN
fnp-5809	225	11	approaches	approach	NOUN
fnp-5809	225	12	are	be	AUX
fnp-5809	225	13	combined	combine	VERB
fnp-5809	225	14	[	[	PUNCT
fnp-5809	225	15	sturm	sturm	X
fnp-5809	225	16	et	et	PROPN
fnp-5809	225	17	al	al	PROPN
fnp-5809	225	18	.	.	PROPN
fnp-5809	225	19	,	,	PUNCT
fnp-5809	225	20	2023	2023	NUM
fnp-5809	225	21	]	]	PUNCT
fnp-5809	225	22	.	.	PUNCT
fnp-5809	226	1	over	over	ADP
fnp-5809	226	2	the	the	DET
fnp-5809	226	3	recent	recent	ADJ
fnp-5809	226	4	years	year	NOUN
fnp-5809	226	5	,	,	PUNCT
fnp-5809	226	6	neuropathology	neuropathology	NOUN
fnp-5809	226	7	was	be	AUX
fnp-5809	226	8	always	always	ADV
fnp-5809	226	9	at	at	ADP
fnp-5809	226	10	the	the	DET
fnp-5809	226	11	forefront	forefront	NOUN
fnp-5809	226	12	regarding	regard	VERB
fnp-5809	226	13	technical	technical	ADJ
fnp-5809	226	14	development	development	NOUN
fnp-5809	226	15	(	(	PUNCT
fnp-5809	226	16	e.g.	e.g.	ADV
fnp-5809	226	17	methylation	methylation	NOUN
fnp-5809	226	18	profiling	profiling	NOUN
fnp-5809	226	19	)	)	PUNCT
fnp-5809	226	20	and	and	CCONJ
fnp-5809	226	21	diagnostic	diagnostic	ADJ
fnp-5809	226	22	precision	precision	NOUN
fnp-5809	226	23	in	in	ADP
fnp-5809	226	24	oncology	oncology	NOUN
fnp-5809	226	25	(	(	PUNCT
fnp-5809	226	26	e.g.	e.g.	ADV
fnp-5809	226	27	entity	entity	NOUN
fnp-5809	226	28	specific	specific	ADJ
fnp-5809	226	29	mutations	mutation	NOUN
fnp-5809	226	30	such	such	ADJ
fnp-5809	226	31	as	as	ADP
fnp-5809	226	32	idh1	idh1	PROPN
fnp-5809	226	33	/	/	SYM
fnp-5809	226	34	idh2	idh2	PROPN
fnp-5809	226	35	,	,	PUNCT
fnp-5809	226	36	h3k27	h3k27	PROPN
fnp-5809	226	37	m	m	PROPN
fnp-5809	226	38	,	,	PUNCT
fnp-5809	226	39	atrx	atrx	VERB
fnp-5809	226	40	only	only	ADV
fnp-5809	226	41	to	to	PART
fnp-5809	226	42	name	name	VERB
fnp-5809	226	43	a	a	DET
fnp-5809	226	44	few	few	ADJ
fnp-5809	226	45	)	)	PUNCT
fnp-5809	226	46	,	,	PUNCT
fnp-5809	226	47	subsequently	subsequently	ADV
fnp-5809	226	48	also	also	ADV
fnp-5809	226	49	impacting	impact	VERB
fnp-5809	226	50	other	other	ADJ
fnp-5809	226	51	oncological	oncological	ADJ
fnp-5809	226	52	domains	domain	NOUN
fnp-5809	226	53	.	.	PUNCT
fnp-5809	227	1	these	these	DET
fnp-5809	227	2	developments	development	NOUN
fnp-5809	227	3	prompted	prompt	VERB
fnp-5809	227	4	an	an	DET
fnp-5809	227	5	extremely	extremely	ADV
fnp-5809	227	6	rapid	rapid	ADJ
fnp-5809	227	7	clinical	clinical	ADJ
fnp-5809	227	8	translation	translation	NOUN
fnp-5809	227	9	focusing	focus	VERB
fnp-5809	227	10	on	on	ADP
fnp-5809	227	11	specific	specific	ADJ
fnp-5809	227	12	drug	drug	NOUN
fnp-5809	227	13	targets	target	NOUN
fnp-5809	227	14	such	such	ADJ
fnp-5809	227	15	as	as	ADP
fnp-5809	227	16	h3k27	h3k27	PROPN
fnp-5809	227	17	m	m	PROPN
fnp-5809	227	18	,	,	PUNCT
fnp-5809	227	19	idh1	idh1	PROPN
fnp-5809	227	20	/	/	SYM
fnp-5809	227	21	idh2	idh2	PROPN
fnp-5809	227	22	or	or	CCONJ
fnp-5809	227	23	mrd	mrd	ADJ
fnp-5809	227	24	tumors	tumor	NOUN
fnp-5809	228	1	[	[	X
fnp-5809	228	2	hadad	hadad	PROPN
fnp-5809	228	3	et	et	PROPN
fnp-5809	228	4	al	al	PROPN
fnp-5809	228	5	.	.	PROPN
fnp-5809	228	6	,	,	PUNCT
fnp-5809	228	7	2023	2023	NUM
fnp-5809	228	8	;	;	PUNCT
fnp-5809	228	9	grassl	grassl	VERB
fnp-5809	228	10	et	et	PROPN
fnp-5809	228	11	al	al	PROPN
fnp-5809	228	12	.	.	PROPN
fnp-5809	228	13	,	,	PUNCT
fnp-5809	228	14	2023	2023	NUM
fnp-5809	228	15	;	;	PUNCT
fnp-5809	228	16	mellinghoff	mellinghoff	NOUN
fnp-5809	228	17	et	et	PROPN
fnp-5809	228	18	al	al	PROPN
fnp-5809	228	19	.	.	PROPN
fnp-5809	228	20	,	,	PUNCT
fnp-5809	228	21	2023	2023	NUM
fnp-5809	228	22	]	]	PUNCT
fnp-5809	228	23	.	.	PUNCT
fnp-5809	229	1	in	in	ADP
fnp-5809	229	2	conclusion	conclusion	NOUN
fnp-5809	229	3	,	,	PUNCT
fnp-5809	229	4	it	it	PRON
fnp-5809	229	5	is	be	AUX
fnp-5809	229	6	fascinating	fascinating	ADJ
fnp-5809	229	7	to	to	PART
fnp-5809	229	8	see	see	VERB
fnp-5809	229	9	how	how	SCONJ
fnp-5809	229	10	fast	fast	ADV
fnp-5809	229	11	the	the	DET
fnp-5809	229	12	improvements	improvement	NOUN
fnp-5809	229	13	in	in	ADP
fnp-5809	229	14	diagnostic	diagnostic	ADJ
fnp-5809	229	15	neuropathology	neuropathology	NOUN
fnp-5809	229	16	with	with	ADP
fnp-5809	229	17	the	the	DET
fnp-5809	229	18	definition	definition	NOUN
fnp-5809	229	19	of	of	ADP
fnp-5809	229	20	specific	specific	ADJ
fnp-5809	229	21	treatment	treatment	NOUN
fnp-5809	229	22	targets	target	NOUN
fnp-5809	229	23	reached	reach	VERB
fnp-5809	229	24	the	the	DET
fnp-5809	229	25	bedside	bedside	NOUN
fnp-5809	229	26	.	.	PUNCT
fnp-5809	230	1	after	after	ADP
fnp-5809	230	2	having	having	AUX
fnp-5809	230	3	shown	show	VERB
fnp-5809	230	4	drug	drug	NOUN
fnp-5809	230	5	safety	safety	NOUN
fnp-5809	230	6	and	and	CCONJ
fnp-5809	230	7	initial	initial	ADJ
fnp-5809	230	8	clinical	clinical	ADJ
fnp-5809	230	9	efficacy	efficacy	NOUN
fnp-5809	230	10	,	,	PUNCT
fnp-5809	230	11	larger	large	ADJ
fnp-5809	230	12	clinical	clinical	ADJ
fnp-5809	230	13	trials	trial	NOUN
fnp-5809	230	14	are	be	AUX
fnp-5809	230	15	now	now	ADV
fnp-5809	230	16	necessary	necessary	ADJ
fnp-5809	230	17	to	to	PART
fnp-5809	230	18	define	define	VERB
fnp-5809	230	19	best	good	ADJ
fnp-5809	230	20	treatment	treatment	NOUN
fnp-5809	230	21	schemes	scheme	NOUN
fnp-5809	230	22	.	.	PUNCT
fnp-5809	231	1	acknowledgements	acknowledgement	NOUN
fnp-5809	231	2	the	the	DET
fnp-5809	231	3	figures	figure	NOUN
fnp-5809	231	4	were	be	AUX
fnp-5809	231	5	prepared	prepare	VERB
fnp-5809	231	6	using	use	VERB
fnp-5809	231	7	https://biorender.com	https://biorender.com	X
fnp-5809	231	8	figure	figure	VERB
fnp-5809	231	9	creation	creation	NOUN
fnp-5809	231	10	tool	tool	NOUN
fnp-5809	231	11	.	.	PUNCT
fnp-5809	232	1	the	the	DET
fnp-5809	232	2	author	author	NOUN
fnp-5809	232	3	would	would	AUX
fnp-5809	232	4	like	like	VERB
fnp-5809	232	5	to	to	PART
fnp-5809	232	6	thank	thank	VERB
fnp-5809	232	7	prof	prof	PROPN
fnp-5809	232	8	.	.	PUNCT
fnp-5809	233	1	patrick	patrick	PROPN
fnp-5809	233	2	harter	harter	PROPN
fnp-5809	233	3	,	,	PUNCT
fnp-5809	233	4	prof	prof	PROPN
fnp-5809	233	5	.	.	PUNCT
fnp-5809	234	1	david	david	PROPN
fnp-5809	234	2	capper	capper	PROPN
fnp-5809	234	3	,	,	PUNCT
fnp-5809	234	4	dr	dr	PROPN
fnp-5809	234	5	.	.	PROPN
fnp-5809	234	6	ann	ann	PROPN
fnp-5809	234	7	-	-	PUNCT
fnp-5809	234	8	christin	christin	PROPN
fnp-5809	234	9	hau	hau	PROPN
fnp-5809	234	10	,	,	PUNCT
fnp-5809	234	11	prof	prof	PROPN
fnp-5809	234	12	.	.	PUNCT
fnp-5809	235	1	joachim	joachim	PROPN
fnp-5809	235	2	steinbach	steinbach	PROPN
fnp-5809	235	3	,	,	PUNCT
fnp-5809	235	4	pd	pd	PROPN
fnp-5809	235	5	dr	dr	PROPN
fnp-5809	235	6	.	.	PROPN
fnp-5809	235	7	michael	michael	PROPN
fnp-5809	235	8	ronellenfitsch	ronellenfitsch	PROPN
fnp-5809	235	9	and	and	CCONJ
fnp-5809	235	10	prof	prof	PROPN
fnp-5809	235	11	.	.	PROPN
fnp-5809	235	12	werner	werner	PROPN
fnp-5809	235	13	stenzel	stenzel	PROPN
fnp-5809	235	14	for	for	ADP
fnp-5809	235	15	one	one	NUM
fnp-5809	235	16	or	or	CCONJ
fnp-5809	235	17	the	the	DET
fnp-5809	235	18	other	other	ADJ
fnp-5809	235	19	discussion	discussion	NOUN
fnp-5809	235	20	around	around	ADP
fnp-5809	235	21	neurooncological	neurooncological	ADJ
fnp-5809	235	22	topics	topic	NOUN
fnp-5809	235	23	discussed	discuss	VERB
fnp-5809	235	24	in	in	ADP
fnp-5809	235	25	this	this	DET
fnp-5809	235	26	paper	paper	NOUN
fnp-5809	235	27	.	.	PUNCT
fnp-5809	236	1	conflicts	conflict	NOUN
fnp-5809	236	2	of	of	ADP
fnp-5809	236	3	interest	interest	NOUN
fnp-5809	236	4	statement	statement	NOUN
fnp-5809	236	5	the	the	DET
fnp-5809	236	6	author	author	NOUN
fnp-5809	236	7	does	do	AUX
fnp-5809	236	8	not	not	PART
fnp-5809	236	9	have	have	VERB
fnp-5809	236	10	any	any	DET
fnp-5809	236	11	conflict	conflict	NOUN
fnp-5809	236	12	of	of	ADP
fnp-5809	236	13	interest	interest	NOUN
fnp-5809	236	14	to	to	PART
fnp-5809	236	15	declare	declare	VERB
fnp-5809	236	16	.	.	PUNCT
fnp-5809	237	1	funding	funding	NOUN
fnp-5809	237	2	statement	statement	NOUN
fnp-5809	237	3	mm	mm	PROPN
fnp-5809	237	4	would	would	AUX
fnp-5809	237	5	like	like	VERB
fnp-5809	237	6	to	to	PART
fnp-5809	237	7	thank	thank	VERB
fnp-5809	237	8	the	the	DET
fnp-5809	237	9	luxembourg	luxembourg	PROPN
fnp-5809	237	10	national	national	PROPN
fnp-5809	237	11	research	research	PROPN
fnp-5809	237	12	fond	fond	ADJ
fnp-5809	237	13	(	(	PUNCT
fnp-5809	237	14	fnr	fnr	PROPN
fnp-5809	237	15	)	)	PUNCT
fnp-5809	237	16	for	for	ADP
fnp-5809	237	17	the	the	DET
fnp-5809	237	18	support	support	NOUN
fnp-5809	237	19	(	(	PUNCT
fnp-5809	237	20	fnr	fnr	PROPN
fnp-5809	237	21	pearl	pearl	NOUN
fnp-5809	237	22	p16	p16	PROPN
fnp-5809	237	23	/	/	SYM
fnp-5809	237	24	bm/11192868	bm/11192868	ADJ
fnp-5809	237	25	grant	grant	NOUN
fnp-5809	237	26	)	)	PUNCT
fnp-5809	237	27	.	.	PUNCT
fnp-5809	238	1	references	reference	NOUN
fnp-5809	238	2	1	1	NUM
fnp-5809	238	3	.	.	PUNCT
fnp-5809	238	4	alsabbagh	alsabbagh	PROPN
fnp-5809	238	5	r	r	PROPN
fnp-5809	238	6	,	,	PUNCT
fnp-5809	238	7	ahmed	ahmed	PROPN
fnp-5809	238	8	m	m	PROPN
fnp-5809	238	9	,	,	PUNCT
fnp-5809	238	10	alqudah	alqudah	PROPN
fnp-5809	238	11	may	may	AUX
fnp-5809	238	12	,	,	PUNCT
fnp-5809	238	13	hamoudi	hamoudi	ADJ
fnp-5809	238	14	r	r	NOUN
fnp-5809	238	15	,	,	PUNCT
fnp-5809	238	16	harati	harati	PROPN
fnp-5809	238	17	r.	r.	PROPN
fnp-5809	238	18	insights	insight	NOUN
fnp-5809	238	19	into	into	ADP
fnp-5809	238	20	the	the	DET
fnp-5809	238	21	molecular	molecular	ADJ
fnp-5809	238	22	mechanisms	mechanism	NOUN
fnp-5809	238	23	mediating	mediate	VERB
fnp-5809	238	24	extravasation	extravasation	NOUN
fnp-5809	238	25	in	in	ADP
fnp-5809	238	26	brain	brain	NOUN
fnp-5809	238	27	metastasis	metastasis	NOUN
fnp-5809	238	28	of	of	ADP
fnp-5809	238	29	breast	breast	NOUN
fnp-5809	238	30	cancer	cancer	NOUN
fnp-5809	238	31	,	,	PUNCT
fnp-5809	238	32	melanoma	melanoma	NOUN
fnp-5809	238	33	,	,	PUNCT
fnp-5809	238	34	and	and	CCONJ
fnp-5809	238	35	lung	lung	NOUN
fnp-5809	238	36	cancer	cancer	NOUN
fnp-5809	238	37	.	.	PUNCT
fnp-5809	239	1	cancers	cancer	NOUN
fnp-5809	239	2	(	(	PUNCT
fnp-5809	239	3	basel	basel	PROPN
fnp-5809	239	4	)	)	PUNCT
fnp-5809	239	5	.	.	PUNCT
fnp-5809	240	1	2023	2023	NUM
fnp-5809	240	2	apr	apr	NOUN
fnp-5809	240	3	12;15(8):2258	12;15(8):2258	NUM
fnp-5809	240	4	.	.	PUNCT
fnp-5809	241	1	https://doi.org/10.3390/cancers15082258	https://doi.org/10.3390/cancers15082258	PROPN
fnp-5809	241	2	.	.	PUNCT
fnp-5809	242	1	pmid	pmid	NOUN
fnp-5809	242	2	:	:	PUNCT
fnp-5809	242	3	37190188	37190188	NUM
fnp-5809	242	4	.	.	PUNCT
fnp-5809	243	1	2	2	NUM
fnp-5809	243	2	.	.	NUM
fnp-5809	243	3	bogumil	bogumil	PROPN
fnp-5809	243	4	h	h	PROPN
fnp-5809	243	5	,	,	PUNCT
fnp-5809	243	6	sill	sill	NOUN
fnp-5809	243	7	m	m	PROPN
fnp-5809	243	8	,	,	PUNCT
fnp-5809	243	9	schrimpf	schrimpf	NOUN
fnp-5809	243	10	d	d	NOUN
fnp-5809	243	11	,	,	PUNCT
fnp-5809	243	12	ismer	ismer	NOUN
fnp-5809	243	13	b	b	PROPN
fnp-5809	243	14	,	,	PUNCT
fnp-5809	243	15	blume	blume	PROPN
fnp-5809	243	16	c	c	NOUN
fnp-5809	243	17	,	,	PUNCT
fnp-5809	243	18	rahmanzade	rahmanzade	NOUN
fnp-5809	243	19	r	r	NOUN
fnp-5809	243	20	,	,	PUNCT
fnp-5809	243	21	hinz	hinz	PROPN
fnp-5809	243	22	f	f	PROPN
fnp-5809	243	23	,	,	PUNCT
fnp-5809	243	24	cherkezov	cherkezov	VERB
fnp-5809	243	25	a	a	DET
fnp-5809	243	26	,	,	PUNCT
fnp-5809	243	27	banan	banan	NOUN
fnp-5809	243	28	r	r	NOUN
fnp-5809	243	29	,	,	PUNCT
fnp-5809	243	30	friedel	friedel	PROPN
fnp-5809	243	31	d	d	PROPN
fnp-5809	243	32	,	,	PUNCT
fnp-5809	243	33	reuss	reuss	PROPN
fnp-5809	243	34	de	de	X
fnp-5809	243	35	,	,	PUNCT
fnp-5809	243	36	selt	selt	PROPN
fnp-5809	243	37	f	f	NOUN
fnp-5809	243	38	,	,	PUNCT
fnp-5809	243	39	ecker	ecker	PROPN
fnp-5809	243	40	j	j	PROPN
fnp-5809	243	41	,	,	PUNCT
fnp-5809	243	42	milde	milde	PROPN
fnp-5809	243	43	t	t	PROPN
fnp-5809	243	44	,	,	PUNCT
fnp-5809	243	45	pajtler	pajtler	ADJ
fnp-5809	243	46	kw	kw	PROPN
fnp-5809	243	47	,	,	PUNCT
fnp-5809	243	48	schittenhelm	schittenhelm	PROPN
fnp-5809	243	49	j	j	PROPN
fnp-5809	243	50	,	,	PUNCT
fnp-5809	243	51	hench	hench	PROPN
fnp-5809	243	52	j	j	PROPN
fnp-5809	243	53	,	,	PUNCT
fnp-5809	243	54	frank	frank	PROPN
fnp-5809	243	55	s	s	PROPN
fnp-5809	243	56	,	,	PUNCT
fnp-5809	243	57	boldt	boldt	PROPN
fnp-5809	243	58	hb	hb	PROPN
fnp-5809	243	59	,	,	PUNCT
fnp-5809	243	60	kristensen	kristensen	PROPN
fnp-5809	243	61	bw	bw	PROPN
fnp-5809	243	62	,	,	PUNCT
fnp-5809	243	63	scheie	scheie	PROPN
fnp-5809	243	64	d	d	PROPN
fnp-5809	243	65	,	,	PUNCT
fnp-5809	243	66	melchior	melchior	PROPN
fnp-5809	243	67	lc	lc	PROPN
fnp-5809	243	68	,	,	PUNCT
fnp-5809	243	69	olesen	olesen	VERB
fnp-5809	243	70	v	v	NOUN
fnp-5809	243	71	,	,	PUNCT
fnp-5809	243	72	sehested	seheste	VERB
fnp-5809	243	73	a	a	PRON
fnp-5809	243	74	,	,	PUNCT
fnp-5809	243	75	boué	boué	PROPN
fnp-5809	243	76	dr	dr	PROPN
fnp-5809	243	77	,	,	PUNCT
fnp-5809	243	78	abdullaev	abdullaev	PROPN
fnp-5809	243	79	z	z	PROPN
fnp-5809	243	80	,	,	PUNCT
fnp-5809	243	81	satgunaseelan	satgunaseelan	PROPN
fnp-5809	243	82	l	l	PROPN
fnp-5809	243	83	,	,	PUNCT
fnp-5809	243	84	kurth	kurth	PROPN
fnp-5809	243	85	i	i	PROPN
fnp-5809	243	86	,	,	PUNCT
fnp-5809	243	87	seidlitz	seidlitz	PROPN
fnp-5809	243	88	a	a	DET
fnp-5809	243	89	,	,	PUNCT
fnp-5809	243	90	white	white	ADJ
fnp-5809	243	91	cl	cl	NOUN
fnp-5809	243	92	,	,	PUNCT
fnp-5809	243	93	ng	ng	PROPN
fnp-5809	243	94	hk	hk	PROPN
fnp-5809	243	95	,	,	PUNCT
fnp-5809	243	96	shi	shi	PROPN
fnp-5809	243	97	zf	zf	PROPN
fnp-5809	243	98	,	,	PUNCT
fnp-5809	243	99	haberler	haberler	NOUN
fnp-5809	243	100	c	c	NOUN
fnp-5809	243	101	,	,	PUNCT
fnp-5809	243	102	deckert	deckert	VERB
fnp-5809	243	103	m	m	PROPN
fnp-5809	243	104	,	,	PUNCT
fnp-5809	243	105	timmer	timmer	PROPN
fnp-5809	243	106	m	m	PROPN
fnp-5809	243	107	,	,	PUNCT
fnp-5809	243	108	goldbrunner	goldbrunner	NOUN
fnp-5809	243	109	r	r	NOUN
fnp-5809	243	110	,	,	PUNCT
fnp-5809	243	111	tauziède	tauziède	VERB
fnp-5809	243	112	-	-	PUNCT
fnp-5809	243	113	espariat	espariat	PROPN
fnp-5809	243	114	a	a	NOUN
fnp-5809	243	115	,	,	PUNCT
fnp-5809	243	116	varlet	varlet	NOUN
fnp-5809	243	117	p	p	NOUN
fnp-5809	243	118	,	,	PUNCT
fnp-5809	243	119	brandner	brandner	NOUN
fnp-5809	243	120	s	s	PROPN
fnp-5809	243	121	,	,	PUNCT
fnp-5809	243	122	alexandrescu	alexandrescu	PROPN
fnp-5809	243	123	s	s	PART
fnp-5809	243	124	,	,	PUNCT
fnp-5809	243	125	snuderl	snuderl	PROPN
fnp-5809	243	126	m	m	PROPN
fnp-5809	243	127	,	,	PUNCT
fnp-5809	243	128	aldape	aldape	PROPN
fnp-5809	243	129	k	k	PROPN
fnp-5809	243	130	,	,	PUNCT
fnp-5809	243	131	korshunov	korshunov	PROPN
fnp-5809	243	132	a	a	PRON
fnp-5809	243	133	,	,	PUNCT
fnp-5809	243	134	witt	witt	PROPN
fnp-5809	243	135	o	o	NOUN
fnp-5809	243	136	,	,	PUNCT
fnp-5809	243	137	herold	herold	PROPN
fnp-5809	243	138	-	-	PUNCT
fnp-5809	243	139	mende	mende	PROPN
fnp-5809	243	140	c	c	PROPN
fnp-5809	243	141	,	,	PUNCT
fnp-5809	243	142	unterberg	unterberg	PROPN
fnp-5809	243	143	a	a	PRON
fnp-5809	243	144	,	,	PUNCT
fnp-5809	243	145	wick	wick	PROPN
fnp-5809	243	146	w	w	PROPN
fnp-5809	243	147	,	,	PUNCT
fnp-5809	243	148	pfister	pfister	PROPN
fnp-5809	243	149	sm	sm	PROPN
fnp-5809	243	150	,	,	PUNCT
fnp-5809	243	151	von	von	PROPN
fnp-5809	243	152	deimling	deimle	VERB
fnp-5809	243	153	a	a	DET
fnp-5809	243	154	,	,	PUNCT
fnp-5809	243	155	jones	jones	PROPN
fnp-5809	243	156	dtw	dtw	PROPN
fnp-5809	243	157	,	,	PUNCT
fnp-5809	243	158	sahm	sahm	PROPN
fnp-5809	243	159	f	f	PROPN
fnp-5809	243	160	,	,	PUNCT
fnp-5809	243	161	sievers	sievers	PROPN
fnp-5809	243	162	p.	p.	NOUN
fnp-5809	243	163	glioneuronal	glioneuronal	ADJ
fnp-5809	243	164	tumor	tumor	NOUN
fnp-5809	243	165	with	with	ADP
fnp-5809	243	166	atrx	atrx	PROPN
fnp-5809	243	167	alteration	alteration	NOUN
fnp-5809	243	168	,	,	PUNCT
fnp-5809	243	169	kinase	kinase	NOUN
fnp-5809	243	170	fusion	fusion	NOUN
fnp-5809	243	171	and	and	CCONJ
fnp-5809	243	172	anaplastic	anaplastic	ADJ
fnp-5809	243	173	features	feature	NOUN
fnp-5809	243	174	(	(	PUNCT
fnp-5809	243	175	gtaka	gtaka	NOUN
fnp-5809	243	176	):	):	PUNCT
fnp-5809	243	177	a	a	DET
fnp-5809	243	178	molecularly	molecularly	ADV
fnp-5809	243	179	distinct	distinct	ADJ
fnp-5809	243	180	brain	brain	NOUN
fnp-5809	243	181	tumor	tumor	NOUN
fnp-5809	243	182	type	type	NOUN
fnp-5809	243	183	with	with	ADP
fnp-5809	243	184	recurrent	recurrent	ADJ
fnp-5809	243	185	ntrk	ntrk	NOUN
fnp-5809	243	186	gene	gene	NOUN
fnp-5809	243	187	fusions	fusion	NOUN
fnp-5809	243	188	.	.	PUNCT
fnp-5809	244	1	acta	acta	PROPN
fnp-5809	244	2	neuropathol	neuropathol	PROPN
fnp-5809	244	3	.	.	PUNCT
fnp-5809	245	1	2023	2023	NUM
fnp-5809	245	2	may;145(5):667	may;145(5):667	NOUN
fnp-5809	245	3	-	-	PUNCT
fnp-5809	245	4	680	680	NUM
fnp-5809	245	5	.	.	PUNCT
fnp-5809	246	1	https://doi.org/10.1007/s00401-023-02558-0	https://doi.org/10.1007/s00401-023-02558-0	NUM
fnp-5809	246	2	.	.	PUNCT
fnp-5809	247	1	pmid	pmid	NOUN
fnp-5809	247	2	:	:	PUNCT
fnp-5809	247	3	36933012	36933012	NUM
fnp-5809	247	4	.	.	PUNCT
fnp-5809	248	1	3	3	X
fnp-5809	248	2	.	.	X
fnp-5809	248	3	bouffet	bouffet	PROPN
fnp-5809	248	4	e	e	PROPN
fnp-5809	248	5	,	,	PUNCT
fnp-5809	248	6	larouche	larouche	PROPN
fnp-5809	248	7	v	v	PROPN
fnp-5809	248	8	,	,	PUNCT
fnp-5809	248	9	campbell	campbell	PROPN
fnp-5809	248	10	bb	bb	PROPN
fnp-5809	248	11	,	,	PUNCT
fnp-5809	248	12	merico	merico	PROPN
fnp-5809	248	13	d	d	PROPN
fnp-5809	248	14	,	,	PUNCT
fnp-5809	248	15	de	de	PROPN
fnp-5809	248	16	borja	borja	PROPN
fnp-5809	248	17	r	r	PROPN
fnp-5809	248	18	,	,	PUNCT
fnp-5809	248	19	aronson	aronson	PROPN
fnp-5809	248	20	m	m	PROPN
fnp-5809	248	21	,	,	PUNCT
fnp-5809	248	22	durno	durno	PROPN
fnp-5809	248	23	c	c	NOUN
fnp-5809	248	24	,	,	PUNCT
fnp-5809	248	25	krueger	krueger	PROPN
fnp-5809	248	26	j	j	PROPN
fnp-5809	248	27	,	,	PUNCT
fnp-5809	248	28	cabric	cabric	PROPN
fnp-5809	248	29	v	v	NOUN
fnp-5809	248	30	,	,	PUNCT
fnp-5809	248	31	ramaswamy	ramaswamy	ADJ
fnp-5809	248	32	v	v	NOUN
fnp-5809	248	33	,	,	PUNCT
fnp-5809	248	34	zhukova	zhukova	PROPN
fnp-5809	248	35	n	n	CCONJ
fnp-5809	248	36	,	,	PUNCT
fnp-5809	248	37	mason	mason	PROPN
fnp-5809	248	38	g	g	PROPN
fnp-5809	248	39	,	,	PUNCT
fnp-5809	248	40	farah	farah	PROPN
fnp-5809	248	41	r	r	PROPN
fnp-5809	248	42	,	,	PUNCT
fnp-5809	248	43	afzal	afzal	PROPN
fnp-5809	248	44	s	s	PROPN
fnp-5809	248	45	,	,	PUNCT
fnp-5809	248	46	yalon	yalon	NOUN
fnp-5809	248	47	m	m	PROPN
fnp-5809	248	48	,	,	PUNCT
fnp-5809	248	49	rechavi	rechavi	VERB
fnp-5809	248	50	g	g	NOUN
fnp-5809	248	51	,	,	PUNCT
fnp-5809	248	52	magimairajan	magimairajan	NOUN
fnp-5809	248	53	v	v	NOUN
fnp-5809	248	54	,	,	PUNCT
fnp-5809	248	55	walsh	walsh	NOUN
fnp-5809	248	56	mf	mf	PROPN
fnp-5809	248	57	,	,	PUNCT
fnp-5809	248	58	constantini	constantini	NOUN
fnp-5809	248	59	s	s	PROPN
fnp-5809	248	60	,	,	PUNCT
fnp-5809	248	61	dvir	dvir	PROPN
fnp-5809	248	62	r	r	NOUN
fnp-5809	248	63	,	,	PUNCT
fnp-5809	248	64	elhasid	elhasid	ADJ
fnp-5809	248	65	r	r	NOUN
fnp-5809	248	66	,	,	PUNCT
fnp-5809	248	67	reddy	reddy	PROPN
fnp-5809	248	68	a	a	PROPN
fnp-5809	248	69	,	,	PUNCT
fnp-5809	248	70	osborn	osborn	PROPN
fnp-5809	248	71	m	m	PROPN
fnp-5809	248	72	,	,	PUNCT
fnp-5809	248	73	sullivan	sullivan	PROPN
fnp-5809	248	74	m	m	PROPN
fnp-5809	248	75	,	,	PUNCT
fnp-5809	248	76	hansford	hansford	PROPN
fnp-5809	248	77	j	j	PROPN
fnp-5809	248	78	,	,	PUNCT
fnp-5809	248	79	dodgshun	dodgshun	PROPN
fnp-5809	248	80	a	a	PRON
fnp-5809	248	81	,	,	PUNCT
fnp-5809	248	82	klauber	klauber	NOUN
fnp-5809	248	83	-	-	PUNCT
fnp-5809	248	84	demore	demore	PROPN
fnp-5809	248	85	n	n	CCONJ
fnp-5809	248	86	,	,	PUNCT
fnp-5809	248	87	peterson	peterson	PROPN
fnp-5809	248	88	l	l	PROPN
fnp-5809	248	89	,	,	PUNCT
fnp-5809	248	90	patel	patel	PROPN
fnp-5809	248	91	s	s	PART
fnp-5809	248	92	,	,	PUNCT
fnp-5809	248	93	lindhorst	lindhorst	PROPN
fnp-5809	248	94	s	s	PROPN
fnp-5809	248	95	,	,	PUNCT
fnp-5809	248	96	atkinson	atkinson	PROPN
fnp-5809	248	97	j	j	PROPN
fnp-5809	248	98	,	,	PUNCT
fnp-5809	248	99	cohen	cohen	PROPN
fnp-5809	248	100	z	z	PROPN
fnp-5809	248	101	,	,	PUNCT
fnp-5809	248	102	laframboise	laframboise	NOUN
fnp-5809	248	103	r	r	NOUN
fnp-5809	248	104	,	,	PUNCT
fnp-5809	248	105	dirks	dirk	NOUN
fnp-5809	248	106	p	p	X
fnp-5809	248	107	,	,	PUNCT
fnp-5809	248	108	taylor	taylor	PROPN
fnp-5809	248	109	m	m	PROPN
fnp-5809	248	110	,	,	PUNCT
fnp-5809	248	111	malkin	malkin	PROPN
fnp-5809	248	112	d	d	PROPN
fnp-5809	248	113	,	,	PUNCT
fnp-5809	248	114	albrecht	albrecht	PROPN
fnp-5809	248	115	s	s	PART
fnp-5809	248	116	,	,	PUNCT
fnp-5809	248	117	dudley	dudley	PROPN
fnp-5809	248	118	rw	rw	NOUN
fnp-5809	248	119	,	,	PUNCT
fnp-5809	248	120	jabado	jabado	NOUN
fnp-5809	248	121	n	n	CCONJ
fnp-5809	248	122	,	,	PUNCT
fnp-5809	248	123	hawkins	hawkins	PROPN
fnp-5809	248	124	ce	ce	PROPN
fnp-5809	248	125	,	,	PUNCT
fnp-5809	248	126	shlien	shlien	VERB
fnp-5809	248	127	a	a	PRON
fnp-5809	248	128	,	,	PUNCT
fnp-5809	248	129	tabori	tabori	NOUN
fnp-5809	248	130	u.	u.	PROPN
fnp-5809	248	131	immune	immune	ADJ
fnp-5809	248	132	checkpoint	checkpoint	NOUN
fnp-5809	248	133	inhibition	inhibition	NOUN
fnp-5809	248	134	for	for	ADP
fnp-5809	248	135	hypermutant	hypermutant	ADJ
fnp-5809	248	136	glioblastoma	glioblastoma	NOUN
fnp-5809	248	137	multiforme	multiforme	NOUN
fnp-5809	248	138	resulting	result	VERB
fnp-5809	248	139	from	from	ADP
fnp-5809	248	140	germline	germline	PROPN
fnp-5809	248	141	biallelic	biallelic	PROPN
fnp-5809	248	142	mismatch	mismatch	PROPN
fnp-5809	248	143	repair	repair	NOUN
fnp-5809	248	144	deficiency	deficiency	NOUN
fnp-5809	248	145	.	.	PUNCT
fnp-5809	249	1	j	j	PROPN
fnp-5809	249	2	clin	clin	PROPN
fnp-5809	249	3	oncol	oncol	PROPN
fnp-5809	249	4	.	.	PUNCT
fnp-5809	250	1	2016	2016	NUM
fnp-5809	250	2	jul	jul	PROPN
fnp-5809	250	3	1;34(19):2206	1;34(19):2206	NUM
fnp-5809	250	4	-	-	SYM
fnp-5809	250	5	11	11	NUM
fnp-5809	250	6	.	.	PUNCT
fnp-5809	251	1	https://doi.org/10.1200/jco.2016.66.6552	https://doi.org/10.1200/jco.2016.66.6552	NOUN
fnp-5809	251	2	.	.	PUNCT
fnp-5809	252	1	pmid	pmid	NOUN
fnp-5809	252	2	:	:	PUNCT
fnp-5809	252	3	27001570	27001570	NUM
fnp-5809	252	4	.	.	PUNCT
fnp-5809	253	1	4	4	X
fnp-5809	253	2	.	.	X
fnp-5809	253	3	capper	capper	PROPN
fnp-5809	253	4	d	d	PROPN
fnp-5809	253	5	,	,	PUNCT
fnp-5809	253	6	jones	jones	PROPN
fnp-5809	253	7	dtw	dtw	PROPN
fnp-5809	253	8	,	,	PUNCT
fnp-5809	253	9	sill	sill	NOUN
fnp-5809	253	10	m	m	PROPN
fnp-5809	253	11	,	,	PUNCT
fnp-5809	253	12	hovestadt	hovestadt	ADJ
fnp-5809	253	13	v	v	NOUN
fnp-5809	253	14	,	,	PUNCT
fnp-5809	253	15	schrimpf	schrimpf	NOUN
fnp-5809	253	16	d	d	PROPN
fnp-5809	253	17	,	,	PUNCT
fnp-5809	253	18	sturm	sturm	PROPN
fnp-5809	253	19	d	d	PROPN
fnp-5809	253	20	,	,	PUNCT
fnp-5809	253	21	koelsche	koelsche	PROPN
fnp-5809	253	22	c	c	PROPN
fnp-5809	253	23	,	,	PUNCT
fnp-5809	253	24	sahm	sahm	PROPN
fnp-5809	253	25	f	f	PROPN
fnp-5809	253	26	,	,	PUNCT
fnp-5809	253	27	chavez	chavez	PROPN
fnp-5809	253	28	l	l	PROPN
fnp-5809	253	29	,	,	PUNCT
fnp-5809	253	30	reuss	reuss	PROPN
fnp-5809	253	31	de	de	PROPN
fnp-5809	253	32	,	,	PUNCT
fnp-5809	253	33	kratz	kratz	PROPN
fnp-5809	253	34	a	a	PROPN
fnp-5809	253	35	,	,	PUNCT
fnp-5809	253	36	wefers	wefers	PROPN
fnp-5809	253	37	ak	ak	PROPN
fnp-5809	253	38	,	,	PUNCT
fnp-5809	253	39	huang	huang	PROPN
fnp-5809	253	40	k	k	PROPN
fnp-5809	253	41	,	,	PUNCT
fnp-5809	253	42	pajtler	pajtler	ADJ
fnp-5809	253	43	kw	kw	PROPN
fnp-5809	253	44	,	,	PUNCT
fnp-5809	253	45	schweizer	schweizer	PROPN
fnp-5809	253	46	l	l	PROPN
fnp-5809	253	47	,	,	PUNCT
fnp-5809	253	48	stichel	stichel	PROPN
fnp-5809	253	49	d	d	PROPN
fnp-5809	253	50	,	,	PUNCT
fnp-5809	253	51	olar	olar	ADJ
fnp-5809	253	52	a	a	PRON
fnp-5809	253	53	,	,	PUNCT
fnp-5809	253	54	engel	engel	PROPN
fnp-5809	253	55	nw	nw	PROPN
fnp-5809	253	56	,	,	PUNCT
fnp-5809	253	57	lindenberg	lindenberg	PROPN
fnp-5809	253	58	k	k	PROPN
fnp-5809	253	59	,	,	PUNCT
fnp-5809	253	60	harter	harter	PROPN
fnp-5809	253	61	pn	pn	PROPN
fnp-5809	253	62	,	,	PUNCT
fnp-5809	253	63	braczynski	braczynski	PROPN
fnp-5809	253	64	ak	ak	PROPN
fnp-5809	253	65	,	,	PUNCT
fnp-5809	253	66	plate	plate	NOUN
fnp-5809	253	67	kh	kh	PROPN
fnp-5809	253	68	,	,	PUNCT
fnp-5809	253	69	dohmen	dohmen	PROPN
fnp-5809	253	70	h	h	NOUN
fnp-5809	253	71	,	,	PUNCT
fnp-5809	253	72	garvalov	garvalov	VERB
fnp-5809	253	73	bk	bk	PROPN
fnp-5809	253	74	,	,	PUNCT
fnp-5809	253	75	coras	coras	PROPN
fnp-5809	253	76	r	r	PROPN
fnp-5809	253	77	,	,	PUNCT
fnp-5809	253	78	hölsken	hölsken	VERB
fnp-5809	253	79	a	a	PRON
fnp-5809	253	80	,	,	PUNCT
fnp-5809	253	81	hewer	hewer	PROPN
fnp-5809	253	82	e	e	NOUN
fnp-5809	253	83	,	,	PUNCT
fnp-5809	253	84	bewerunge	bewerunge	NOUN
fnp-5809	253	85	-	-	PUNCT
fnp-5809	253	86	hudler	hudler	PROPN
fnp-5809	253	87	m	m	PROPN
fnp-5809	253	88	,	,	PUNCT
fnp-5809	253	89	schick	schick	PROPN
fnp-5809	253	90	m	m	PROPN
fnp-5809	253	91	,	,	PUNCT
fnp-5809	253	92	fischer	fischer	PROPN
fnp-5809	253	93	r	r	PROPN
fnp-5809	253	94	,	,	PUNCT
fnp-5809	253	95	beschorner	beschorner	NOUN
fnp-5809	253	96	r	r	NOUN
fnp-5809	253	97	,	,	PUNCT
fnp-5809	253	98	schittenhelm	schittenhelm	PROPN
fnp-5809	253	99	j	j	PROPN
fnp-5809	253	100	,	,	PUNCT
fnp-5809	253	101	staszewski	staszewski	PROPN
fnp-5809	253	102	o	o	PROPN
fnp-5809	253	103	,	,	PUNCT
fnp-5809	253	104	wani	wani	PROPN
fnp-5809	253	105	k	k	PROPN
fnp-5809	253	106	,	,	PUNCT
fnp-5809	253	107	varlet	varlet	VERB
fnp-5809	253	108	p	p	PRON
fnp-5809	253	109	,	,	PUNCT
fnp-5809	253	110	pages	page	NOUN
fnp-5809	253	111	m	m	PRON
fnp-5809	253	112	,	,	PUNCT
fnp-5809	253	113	temming	temme	VERB
fnp-5809	253	114	p	p	PRON
fnp-5809	253	115	,	,	PUNCT
fnp-5809	254	1	lohmann	lohmann	PROPN
fnp-5809	254	2	d	d	PROPN
fnp-5809	254	3	,	,	PUNCT
fnp-5809	254	4	selt	selt	PROPN
fnp-5809	254	5	f	f	PROPN
fnp-5809	254	6	,	,	PUNCT
fnp-5809	254	7	witt	witt	PROPN
fnp-5809	254	8	h	h	PROPN
fnp-5809	254	9	,	,	PUNCT
fnp-5809	254	10	milde	milde	PROPN
fnp-5809	254	11	t	t	PROPN
fnp-5809	254	12	,	,	PUNCT
fnp-5809	254	13	witt	witt	PROPN
fnp-5809	254	14	o	o	NOUN
fnp-5809	254	15	,	,	PUNCT
fnp-5809	254	16	aronica	aronica	PROPN
fnp-5809	254	17	e	e	PROPN
fnp-5809	254	18	,	,	PUNCT
fnp-5809	254	19	giangaspero	giangaspero	PROPN
fnp-5809	254	20	f	f	PROPN
fnp-5809	254	21	,	,	PUNCT
fnp-5809	254	22	rushing	rush	VERB
fnp-5809	254	23	e	e	NOUN
fnp-5809	254	24	,	,	PUNCT
fnp-5809	254	25	scheurlen	scheurlen	PROPN
fnp-5809	254	26	w	w	NOUN
fnp-5809	254	27	,	,	PUNCT
fnp-5809	254	28	geisenberger	geisenberger	ADJ
fnp-5809	254	29	c	c	NOUN
fnp-5809	254	30	,	,	PUNCT
fnp-5809	254	31	rodriguez	rodriguez	PROPN
fnp-5809	254	32	fj	fj	PROPN
fnp-5809	254	33	,	,	PUNCT
fnp-5809	254	34	becker	becker	PROPN
fnp-5809	255	1	a	a	PRON
fnp-5809	255	2	,	,	PUNCT
fnp-5809	255	3	preusser	preusser	PROPN
fnp-5809	255	4	m	m	PROPN
fnp-5809	255	5	,	,	PUNCT
fnp-5809	255	6	haberler	haberler	NOUN
fnp-5809	255	7	c	c	NOUN
fnp-5809	255	8	,	,	PUNCT
fnp-5809	255	9	bjerkvig	bjerkvig	NOUN
fnp-5809	255	10	r	r	NOUN
fnp-5809	255	11	,	,	PUNCT
fnp-5809	255	12	cryan	cryan	PROPN
fnp-5809	255	13	j	j	PROPN
fnp-5809	255	14	,	,	PUNCT
fnp-5809	255	15	farrell	farrell	PROPN
fnp-5809	255	16	m	m	PROPN
fnp-5809	255	17	,	,	PUNCT
fnp-5809	255	18	deckert	deckert	PROPN
fnp-5809	255	19	m	m	PRON
fnp-5809	255	20	,	,	PUNCT
fnp-5809	255	21	hench	hench	PROPN
fnp-5809	255	22	j	j	PROPN
fnp-5809	255	23	,	,	PUNCT
fnp-5809	255	24	frank	frank	PROPN
fnp-5809	255	25	s	s	PROPN
fnp-5809	255	26	,	,	PUNCT
fnp-5809	255	27	serrano	serrano	PROPN
fnp-5809	255	28	j	j	PROPN
fnp-5809	255	29	,	,	PUNCT
fnp-5809	255	30	kannan	kannan	PROPN
fnp-5809	255	31	k	k	PROPN
fnp-5809	255	32	,	,	PUNCT
fnp-5809	255	33	tsirigos	tsirigo	NOUN
fnp-5809	255	34	a	a	DET
fnp-5809	255	35	,	,	PUNCT
fnp-5809	255	36	brück	brück	PROPN
fnp-5809	255	37	w	w	PROPN
fnp-5809	255	38	,	,	PUNCT
fnp-5809	255	39	hofer	hofer	PROPN
fnp-5809	255	40	s	s	PROPN
fnp-5809	255	41	,	,	PUNCT
fnp-5809	255	42	brehmer	brehmer	PROPN
fnp-5809	255	43	s	s	PROPN
fnp-5809	255	44	,	,	PUNCT
fnp-5809	255	45	seiz	seiz	PROPN
fnp-5809	255	46	-	-	PUNCT
fnp-5809	255	47	rosenhagen	rosenhagen	PROPN
fnp-5809	255	48	m	m	PROPN
fnp-5809	255	49	,	,	PUNCT
fnp-5809	255	50	hänggi	hänggi	PROPN
fnp-5809	255	51	d	d	PROPN
fnp-5809	255	52	,	,	PUNCT
fnp-5809	255	53	hans	hans	PROPN
fnp-5809	255	54	v	v	PROPN
fnp-5809	255	55	,	,	PUNCT
fnp-5809	255	56	rozsnoki	rozsnoki	NOUN
fnp-5809	255	57	s	s	PROPN
fnp-5809	255	58	,	,	PUNCT
fnp-5809	255	59	hansford	hansford	PROPN
fnp-5809	255	60	jr	jr	PROPN
fnp-5809	255	61	,	,	PUNCT
fnp-5809	255	62	kohlhof	kohlhof	PROPN
fnp-5809	255	63	p	p	PROPN
fnp-5809	255	64	,	,	PUNCT
fnp-5809	255	65	kristensen	kristensen	PROPN
fnp-5809	255	66	bw	bw	PROPN
fnp-5809	255	67	,	,	PUNCT
fnp-5809	255	68	lechner	lechner	PROPN
fnp-5809	255	69	m	m	PROPN
fnp-5809	255	70	,	,	PUNCT
fnp-5809	255	71	lopes	lopes	PROPN
fnp-5809	255	72	b	b	PROPN
fnp-5809	255	73	,	,	PUNCT
fnp-5809	255	74	mawrin	mawrin	NOUN
fnp-5809	255	75	c	c	NOUN
fnp-5809	255	76	,	,	PUNCT
fnp-5809	255	77	ketter	ketter	NOUN
fnp-5809	255	78	r	r	NOUN
fnp-5809	255	79	,	,	PUNCT
fnp-5809	255	80	kulozik	kulozik	NOUN
fnp-5809	255	81	a	a	PRON
fnp-5809	255	82	,	,	PUNCT
fnp-5809	255	83	khatib	khatib	PROPN
fnp-5809	255	84	z	z	PROPN
fnp-5809	255	85	,	,	PUNCT
fnp-5809	255	86	heppner	heppner	PROPN
fnp-5809	255	87	f	f	PROPN
fnp-5809	255	88	,	,	PUNCT
fnp-5809	255	89	koch	koch	PROPN
fnp-5809	255	90	a	a	PRON
fnp-5809	255	91	,	,	PUNCT
fnp-5809	255	92	jouvet	jouvet	NOUN
fnp-5809	255	93	a	a	PRON
fnp-5809	255	94	,	,	PUNCT
fnp-5809	255	95	keohane	keohane	PROPN
fnp-5809	255	96	c	c	NOUN
fnp-5809	255	97	,	,	PUNCT
fnp-5809	255	98	mühleisen	mühleisen	VERB
fnp-5809	255	99	h	h	NOUN
fnp-5809	255	100	,	,	PUNCT
fnp-5809	255	101	mueller	mueller	PROPN
fnp-5809	255	102	w	w	PROPN
fnp-5809	255	103	,	,	PUNCT
fnp-5809	255	104	pohl	pohl	PROPN
fnp-5809	255	105	u	u	PROPN
fnp-5809	255	106	,	,	PUNCT
fnp-5809	255	107	prinz	prinz	PROPN
fnp-5809	255	108	m	m	PROPN
fnp-5809	255	109	,	,	PUNCT
fnp-5809	255	110	benner	benner	PROPN
fnp-5809	255	111	a	a	PROPN
fnp-5809	255	112	,	,	PUNCT
fnp-5809	255	113	zapatka	zapatka	PROPN
fnp-5809	255	114	m	m	PROPN
fnp-5809	255	115	,	,	PUNCT
fnp-5809	255	116	gottardo	gottardo	PROPN
fnp-5809	255	117	ng	ng	PROPN
fnp-5809	255	118	,	,	PUNCT
fnp-5809	255	119	driever	driever	NOUN
fnp-5809	255	120	ph	ph	PROPN
fnp-5809	255	121	,	,	PUNCT
fnp-5809	255	122	kramm	kramm	PROPN
fnp-5809	255	123	cm	cm	PROPN
fnp-5809	255	124	,	,	PUNCT
fnp-5809	255	125	müller	müller	PROPN
fnp-5809	255	126	hl	hl	PROPN
fnp-5809	255	127	,	,	PUNCT
fnp-5809	255	128	rutkowski	rutkowski	PROPN
fnp-5809	255	129	s	s	PROPN
fnp-5809	255	130	,	,	PUNCT
fnp-5809	255	131	von	von	PROPN
fnp-5809	255	132	hoff	hoff	PROPN
fnp-5809	255	133	k	k	PROPN
fnp-5809	255	134	,	,	PUNCT
fnp-5809	255	135	frühwald	frühwald	PROPN
fnp-5809	255	136	mc	mc	PROPN
fnp-5809	255	137	,	,	PUNCT
fnp-5809	255	138	gnekow	gnekow	ADV
fnp-5809	255	139	a	a	DET
fnp-5809	255	140	,	,	PUNCT
fnp-5809	255	141	fleischhack	fleischhack	NOUN
fnp-5809	255	142	g	g	NOUN
fnp-5809	255	143	,	,	PUNCT
fnp-5809	255	144	tippelt	tippelt	NOUN
fnp-5809	255	145	s	s	NOUN
fnp-5809	255	146	,	,	PUNCT
fnp-5809	255	147	calaminus	calaminus	NOUN
fnp-5809	255	148	g	g	NOUN
fnp-5809	255	149	,	,	PUNCT
fnp-5809	255	150	monoranu	monoranu	NOUN
fnp-5809	255	151	cm	cm	PROPN
fnp-5809	255	152	,	,	PUNCT
fnp-5809	255	153	perry	perry	PROPN
fnp-5809	255	154	a	a	PROPN
fnp-5809	255	155	,	,	PUNCT
fnp-5809	255	156	jones	jones	PROPN
fnp-5809	255	157	c	c	PROPN
fnp-5809	255	158	,	,	PUNCT
fnp-5809	255	159	jacques	jacques	PROPN
fnp-5809	255	160	ts	ts	PROPN
fnp-5809	255	161	,	,	PUNCT
fnp-5809	255	162	radlwimmer	radlwimmer	PROPN
fnp-5809	255	163	b	b	PROPN
fnp-5809	255	164	,	,	PUNCT
fnp-5809	255	165	gessi	gessi	PROPN
fnp-5809	255	166	m	m	PROPN
fnp-5809	255	167	,	,	PUNCT
fnp-5809	255	168	pietsch	pietsch	VERB
fnp-5809	255	169	t	t	PROPN
fnp-5809	255	170	,	,	PUNCT
fnp-5809	255	171	schramm	schramm	PROPN
fnp-5809	255	172	j	j	PROPN
fnp-5809	255	173	,	,	PUNCT
fnp-5809	255	174	schackert	schackert	PROPN
fnp-5809	255	175	g	g	PROPN
fnp-5809	255	176	,	,	PUNCT
fnp-5809	255	177	westphal	westphal	PROPN
fnp-5809	255	178	m	m	PROPN
fnp-5809	255	179	,	,	PUNCT
fnp-5809	255	180	reifenberger	reifenberger	VERB
fnp-5809	255	181	g	g	NOUN
fnp-5809	255	182	,	,	PUNCT
fnp-5809	255	183	wesseling	wessele	VERB
fnp-5809	255	184	p	p	PRON
fnp-5809	255	185	,	,	PUNCT
fnp-5809	255	186	weller	weller	PROPN
fnp-5809	255	187	m	m	PROPN
fnp-5809	255	188	,	,	PUNCT
fnp-5809	255	189	collins	collins	PROPN
fnp-5809	255	190	vp	vp	PROPN
fnp-5809	255	191	,	,	PUNCT
fnp-5809	255	192	blümcke	blümcke	PROPN
fnp-5809	255	193	i	i	PROPN
fnp-5809	255	194	,	,	PUNCT
fnp-5809	255	195	bendszus	bendszus	PROPN
fnp-5809	255	196	m	m	PROPN
fnp-5809	255	197	,	,	PUNCT
fnp-5809	255	198	debus	debus	PROPN
fnp-5809	255	199	j	j	PROPN
fnp-5809	255	200	,	,	PUNCT
fnp-5809	255	201	huang	huang	PROPN
fnp-5809	255	202	a	a	PROPN
fnp-5809	255	203	,	,	PUNCT
fnp-5809	255	204	jabado	jabado	ADJ
fnp-5809	255	205	n	n	CCONJ
fnp-5809	255	206	,	,	PUNCT
fnp-5809	255	207	northcott	northcott	PROPN
fnp-5809	255	208	pa	pa	PROPN
fnp-5809	255	209	,	,	PUNCT
fnp-5809	255	210	paulus	paulus	PROPN
fnp-5809	255	211	w	w	PROPN
fnp-5809	255	212	,	,	PUNCT
fnp-5809	255	213	gajjar	gajjar	NOUN
fnp-5809	255	214	a	a	PRON
fnp-5809	255	215	,	,	PUNCT
fnp-5809	255	216	robinson	robinson	PROPN
fnp-5809	255	217	gw	gw	PROPN
fnp-5809	255	218	,	,	PUNCT
fnp-5809	255	219	taylor	taylor	PROPN
fnp-5809	255	220	md	md	PROPN
fnp-5809	255	221	,	,	PUNCT
fnp-5809	255	222	jaunmuktane	jaunmuktane	PROPN
fnp-5809	255	223	z	z	PROPN
fnp-5809	255	224	,	,	PUNCT
fnp-5809	255	225	ryzhova	ryzhova	PROPN
fnp-5809	255	226	m	m	PROPN
fnp-5809	255	227	,	,	PUNCT
fnp-5809	255	228	platten	platten	PROPN
fnp-5809	255	229	m	m	PROPN
fnp-5809	255	230	,	,	PUNCT
fnp-5809	255	231	unterberg	unterberg	PROPN
fnp-5809	255	232	a	a	PRON
fnp-5809	255	233	,	,	PUNCT
fnp-5809	255	234	wick	wick	PROPN
fnp-5809	255	235	w	w	PROPN
fnp-5809	255	236	,	,	PUNCT
fnp-5809	255	237	karajannis	karajannis	PROPN
fnp-5809	255	238	ma	ma	PROPN
fnp-5809	255	239	,	,	PUNCT
fnp-5809	255	240	mittelbronn	mittelbronn	PROPN
fnp-5809	255	241	m	m	PROPN
fnp-5809	255	242	,	,	PUNCT
fnp-5809	255	243	acker	acker	PROPN
fnp-5809	255	244	t	t	PROPN
fnp-5809	255	245	,	,	PUNCT
fnp-5809	255	246	hartmann	hartmann	PROPN
fnp-5809	255	247	c	c	PROPN
fnp-5809	255	248	,	,	PUNCT
fnp-5809	255	249	aldape	aldape	PROPN
fnp-5809	255	250	k	k	PROPN
fnp-5809	255	251	,	,	PUNCT
fnp-5809	255	252	schüller	schüll	ADJ
fnp-5809	255	253	u	u	NOUN
fnp-5809	255	254	,	,	PUNCT
fnp-5809	255	255	buslei	buslei	NOUN
fnp-5809	255	256	r	r	NOUN
fnp-5809	255	257	,	,	PUNCT
fnp-5809	255	258	lichter	lichter	PROPN
fnp-5809	255	259	p	p	PROPN
fnp-5809	255	260	,	,	PUNCT
fnp-5809	255	261	kool	kool	PROPN
fnp-5809	255	262	m	m	PROPN
fnp-5809	255	263	,	,	PUNCT
fnp-5809	255	264	herold	herold	PROPN
fnp-5809	255	265	-	-	PUNCT
fnp-5809	255	266	mende	mende	PROPN
fnp-5809	255	267	c	c	PROPN
fnp-5809	255	268	,	,	PUNCT
fnp-5809	255	269	ellison	ellison	PROPN
fnp-5809	255	270	dw	dw	PROPN
fnp-5809	255	271	,	,	PUNCT
fnp-5809	255	272	hasselblatt	hasselblatt	PROPN
fnp-5809	255	273	m	m	PROPN
fnp-5809	255	274	,	,	PUNCT
fnp-5809	255	275	snuderl	snuderl	PROPN
fnp-5809	255	276	m	m	PROPN
fnp-5809	255	277	,	,	PUNCT
fnp-5809	255	278	brandner	brandner	PROPN
fnp-5809	255	279	s	s	PROPN
fnp-5809	255	280	,	,	PUNCT
fnp-5809	255	281	korshunov	korshunov	PROPN
fnp-5809	255	282	a	a	PROPN
fnp-5809	255	283	,	,	PUNCT
fnp-5809	255	284	von	von	PROPN
fnp-5809	255	285	deimling	deimle	VERB
fnp-5809	255	286	a	a	PRON
fnp-5809	255	287	,	,	PUNCT
fnp-5809	255	288	pfister	pfister	NOUN
fnp-5809	255	289	sm	sm	PROPN
fnp-5809	255	290	.	.	PROPN
fnp-5809	255	291	dna	dna	PROPN
fnp-5809	255	292	methylation	methylation	NOUN
fnp-5809	255	293	-	-	PUNCT
fnp-5809	255	294	based	base	VERB
fnp-5809	255	295	classification	classification	NOUN
fnp-5809	255	296	of	of	ADP
fnp-5809	255	297	central	central	ADJ
fnp-5809	255	298	nervous	nervous	ADJ
fnp-5809	255	299	system	system	NOUN
fnp-5809	255	300	tumours	tumour	VERB
fnp-5809	255	301	.	.	PUNCT
fnp-5809	256	1	nature	nature	NOUN
fnp-5809	256	2	.	.	PUNCT
fnp-5809	257	1	2018	2018	NUM
fnp-5809	257	2	mar	mar	PROPN
fnp-5809	257	3	22;555(7697):469	22;555(7697):469	NUM
fnp-5809	257	4	-	-	SYM
fnp-5809	257	5	474	474	NUM
fnp-5809	257	6	.	.	PUNCT
fnp-5809	258	1	https://doi.org/10.1038/nature26000	https://doi.org/10.1038/nature26000	PROPN
fnp-5809	258	2	.	.	PUNCT
fnp-5809	259	1	pmid	pmid	NOUN
fnp-5809	259	2	:	:	PUNCT
fnp-5809	259	3	29539639	29539639	NUM
fnp-5809	259	4	.	.	PUNCT
fnp-5809	260	1	5	5	X
fnp-5809	260	2	.	.	NUM
fnp-5809	260	3	d'alessandro	d'alessandro	X
fnp-5809	260	4	g	g	NOUN
fnp-5809	260	5	,	,	PUNCT
fnp-5809	260	6	catalano	catalano	PROPN
fnp-5809	260	7	m	m	PROPN
fnp-5809	260	8	,	,	PUNCT
fnp-5809	260	9	sciaccaluga	sciaccaluga	PROPN
fnp-5809	260	10	m	m	NOUN
fnp-5809	260	11	,	,	PUNCT
fnp-5809	260	12	chece	chece	NOUN
fnp-5809	260	13	g	g	PROPN
fnp-5809	260	14	,	,	PUNCT
fnp-5809	260	15	cipriani	cipriani	PROPN
fnp-5809	260	16	r	r	PROPN
fnp-5809	260	17	,	,	PUNCT
fnp-5809	260	18	rosito	rosito	NOUN
fnp-5809	260	19	m	m	PROPN
fnp-5809	260	20	,	,	PUNCT
fnp-5809	260	21	grimaldi	grimaldi	PROPN
fnp-5809	260	22	a	a	X
fnp-5809	260	23	,	,	PUNCT
fnp-5809	260	24	lauro	lauro	PROPN
fnp-5809	260	25	c	c	PROPN
fnp-5809	260	26	,	,	PUNCT
fnp-5809	260	27	cantore	cantore	PROPN
fnp-5809	260	28	g	g	PROPN
fnp-5809	260	29	,	,	PUNCT
fnp-5809	260	30	santoro	santoro	PROPN
fnp-5809	260	31	a	a	PRON
fnp-5809	260	32	,	,	PUNCT
fnp-5809	260	33	fioretti	fioretti	NOUN
fnp-5809	260	34	b	b	NOUN
fnp-5809	260	35	,	,	PUNCT
fnp-5809	260	36	franciolini	franciolini	ADJ
fnp-5809	260	37	f	f	NOUN
fnp-5809	260	38	,	,	PUNCT
fnp-5809	260	39	wulff	wulff	PROPN
fnp-5809	260	40	h	h	PROPN
fnp-5809	260	41	,	,	PUNCT
fnp-5809	260	42	limatola	limatola	PROPN
fnp-5809	260	43	c.	c.	PROPN
fnp-5809	260	44	kca3.1	kca3.1	PROPN
fnp-5809	260	45	channels	channel	NOUN
fnp-5809	260	46	are	be	AUX
fnp-5809	260	47	involved	involve	VERB
fnp-5809	260	48	in	in	ADP
fnp-5809	260	49	the	the	DET
fnp-5809	260	50	infiltrative	infiltrative	ADJ
fnp-5809	260	51	behavior	behavior	NOUN
fnp-5809	260	52	of	of	ADP
fnp-5809	260	53	glioblastoma	glioblastoma	NOUN
fnp-5809	260	54	in	in	ADP
fnp-5809	260	55	vivo	vivo	NOUN
fnp-5809	260	56	.	.	PUNCT
fnp-5809	261	1	cell	cell	NOUN
fnp-5809	261	2	death	death	NOUN
fnp-5809	261	3	dis	dis	PROPN
fnp-5809	261	4	.	.	PUNCT
fnp-5809	262	1	2013	2013	NUM
fnp-5809	262	2	aug	aug	PROPN
fnp-5809	262	3	15;4(8):e773	15;4(8):e773	NUM
fnp-5809	262	4	.	.	PUNCT
fnp-5809	263	1	https://doi.org/10.1038/cddis.2013.279	https://doi.org/10.1038/cddis.2013.279	NOUN
fnp-5809	263	2	.	.	PUNCT
fnp-5809	264	1	pmid	pmid	NOUN
fnp-5809	264	2	:	:	PUNCT
fnp-5809	264	3	23949222	23949222	NUM
fnp-5809	264	4	.	.	PUNCT
fnp-5809	265	1	6	6	X
fnp-5809	265	2	.	.	X
fnp-5809	266	1	euskirchen	euskirchen	PROPN
fnp-5809	266	2	p	p	NOUN
fnp-5809	266	3	,	,	PUNCT
fnp-5809	266	4	bielle	bielle	NOUN
fnp-5809	266	5	f	f	X
fnp-5809	266	6	,	,	PUNCT
fnp-5809	266	7	labreche	labreche	PROPN
fnp-5809	266	8	k	k	PROPN
fnp-5809	266	9	,	,	PUNCT
fnp-5809	266	10	kloosterman	kloosterman	NOUN
fnp-5809	266	11	wp	wp	PROPN
fnp-5809	266	12	,	,	PUNCT
fnp-5809	266	13	rosenberg	rosenberg	PROPN
fnp-5809	266	14	s	s	PROPN
fnp-5809	266	15	,	,	PUNCT
fnp-5809	266	16	daniau	daniau	PROPN
fnp-5809	266	17	m	m	PROPN
fnp-5809	266	18	,	,	PUNCT
fnp-5809	266	19	schmitt	schmitt	PROPN
fnp-5809	266	20	c	c	NOUN
fnp-5809	266	21	,	,	PUNCT
fnp-5809	266	22	masliah	masliah	PROPN
fnp-5809	266	23	-	-	PUNCT
fnp-5809	266	24	planchon	planchon	PROPN
fnp-5809	266	25	j	j	PROPN
fnp-5809	266	26	,	,	PUNCT
fnp-5809	266	27	bourdeaut	bourdeaut	PROPN
fnp-5809	266	28	f	f	PROPN
fnp-5809	266	29	,	,	PUNCT
fnp-5809	266	30	dehais	dehais	PROPN
fnp-5809	266	31	c	c	PROPN
fnp-5809	266	32	,	,	PUNCT
fnp-5809	266	33	marie	marie	PROPN
fnp-5809	266	34	y	y	PROPN
fnp-5809	266	35	,	,	PUNCT
fnp-5809	266	36	delattre	delattre	PROPN
fnp-5809	266	37	jy	jy	PROPN
fnp-5809	266	38	,	,	PUNCT
fnp-5809	266	39	idbaih	idbaih	VERB
fnp-5809	266	40	a.	a.	NOUN
fnp-5809	266	41	same	same	ADJ
fnp-5809	266	42	-	-	PUNCT
fnp-5809	266	43	day	day	NOUN
fnp-5809	266	44	genomic	genomic	NOUN
fnp-5809	266	45	and	and	CCONJ
fnp-5809	266	46	epigenomic	epigenomic	ADJ
fnp-5809	266	47	diagnosis	diagnosis	NOUN
fnp-5809	266	48	of	of	ADP
fnp-5809	266	49	brain	brain	NOUN
fnp-5809	266	50	tumors	tumor	NOUN
fnp-5809	266	51	using	use	VERB
fnp-5809	266	52	real	real	ADJ
fnp-5809	266	53	-	-	PUNCT
fnp-5809	266	54	time	time	NOUN
fnp-5809	266	55	nanopore	nanopore	ADJ
fnp-5809	266	56	sequencing	sequencing	NOUN
fnp-5809	266	57	.	.	PUNCT
fnp-5809	267	1	acta	acta	PROPN
fnp-5809	267	2	neuropathol	neuropathol	PROPN
fnp-5809	267	3	.	.	PUNCT
fnp-5809	268	1	2017	2017	NUM
fnp-5809	268	2	nov;134(5):691	nov;134(5):691	NOUN
fnp-5809	268	3	-	-	PUNCT
fnp-5809	268	4	703	703	NUM
fnp-5809	268	5	.	.	PUNCT
fnp-5809	269	1	https://doi.org/10.1007/s00401-017-1743-5	https://doi.org/10.1007/s00401-017-1743-5	PROPN
fnp-5809	269	2	.	.	PUNCT
fnp-5809	270	1	pmid	pmid	NOUN
fnp-5809	270	2	:	:	PUNCT
fnp-5809	270	3	28638988	28638988	NUM
fnp-5809	270	4	.	.	PUNCT
fnp-5809	271	1	7	7	X
fnp-5809	271	2	.	.	X
fnp-5809	271	3	evans	evans	PROPN
fnp-5809	271	4	kt	kt	PROPN
fnp-5809	271	5	,	,	PUNCT
fnp-5809	271	6	blake	blake	PROPN
fnp-5809	271	7	k	k	PROPN
fnp-5809	271	8	,	,	PUNCT
fnp-5809	271	9	longworth	longworth	NOUN
fnp-5809	271	10	a	a	PRON
fnp-5809	271	11	,	,	PUNCT
fnp-5809	271	12	coburn	coburn	PROPN
fnp-5809	271	13	ma	ma	PROPN
fnp-5809	271	14	,	,	PUNCT
fnp-5809	271	15	insua	insua	NOUN
fnp-5809	271	16	-	-	PUNCT
fnp-5809	271	17	rodríguez	rodríguez	NOUN
fnp-5809	271	18	j	j	PROPN
fnp-5809	271	19	,	,	PUNCT
fnp-5809	271	20	mcmullen	mcmullen	PROPN
fnp-5809	271	21	tp	tp	PROPN
fnp-5809	271	22	,	,	PUNCT
fnp-5809	271	23	nguyen	nguyen	PROPN
fnp-5809	271	24	qh	qh	PROPN
fnp-5809	271	25	,	,	PUNCT
fnp-5809	271	26	ma	ma	PROPN
fnp-5809	271	27	d	d	PROPN
fnp-5809	271	28	,	,	PUNCT
fnp-5809	271	29	lev	lev	PROPN
fnp-5809	271	30	t	t	PROPN
fnp-5809	271	31	,	,	PUNCT
fnp-5809	271	32	hernandez	hernandez	PROPN
fnp-5809	271	33	ga	ga	PROPN
fnp-5809	271	34	,	,	PUNCT
fnp-5809	271	35	oganyan	oganyan	PROPN
fnp-5809	271	36	ak	ak	PROPN
fnp-5809	271	37	,	,	PUNCT
fnp-5809	271	38	orujyan	orujyan	PROPN
fnp-5809	271	39	d	d	PROPN
fnp-5809	271	40	,	,	PUNCT
fnp-5809	271	41	edwards	edwards	PROPN
fnp-5809	271	42	ra	ra	PROPN
fnp-5809	271	43	,	,	PUNCT
fnp-5809	271	44	pridans	pridan	NOUN
fnp-5809	271	45	c	c	PROPN
fnp-5809	271	46	,	,	PUNCT
fnp-5809	271	47	green	green	PROPN
fnp-5809	271	48	kn	kn	PROPN
fnp-5809	271	49	,	,	PUNCT
fnp-5809	271	50	villalta	villalta	PROPN
fnp-5809	271	51	sa	sa	PROPN
fnp-5809	271	52	,	,	PUNCT
fnp-5809	271	53	blurton	blurton	PROPN
fnp-5809	271	54	-	-	PUNCT
fnp-5809	271	55	jones	jones	PROPN
fnp-5809	271	56	m	m	PROPN
fnp-5809	271	57	,	,	PUNCT
fnp-5809	271	58	lawson	lawson	PROPN
fnp-5809	271	59	da	da	PROPN
fnp-5809	271	60	.	.	PUNCT
fnp-5809	272	1	microglia	microglia	PROPN
fnp-5809	272	2	promote	promote	VERB
fnp-5809	272	3	anti	anti	ADJ
fnp-5809	272	4	-	-	ADJ
fnp-5809	272	5	tumour	tumour	ADJ
fnp-5809	272	6	immunity	immunity	NOUN
fnp-5809	272	7	and	and	CCONJ
fnp-5809	272	8	suppress	suppress	VERB
fnp-5809	272	9	breast	breast	NOUN
fnp-5809	272	10	cancer	cancer	NOUN
fnp-5809	272	11	brain	brain	NOUN
fnp-5809	272	12	metastasis	metastasis	NOUN
fnp-5809	272	13	.	.	PUNCT
fnp-5809	273	1	nat	nat	NOUN
fnp-5809	273	2	cell	cell	NOUN
fnp-5809	273	3	biol	biol	PROPN
fnp-5809	273	4	.	.	PUNCT
fnp-5809	274	1	2023	2023	NUM
fnp-5809	274	2	dec;25(12):1848	dec;25(12):1848	NOUN
fnp-5809	274	3	-	-	NOUN
fnp-5809	274	4	1859	1859	NUM
fnp-5809	274	5	.	.	PUNCT
fnp-5809	275	1	https://doi.org/10.1038/s41556-023-01273-y	https://doi.org/10.1038/s41556-023-01273-y	PROPN
fnp-5809	275	2	.	.	PUNCT
fnp-5809	276	1	pmid	pmid	NOUN
fnp-5809	276	2	:	:	PUNCT
fnp-5809	276	3	37957324	37957324	NUM
fnp-5809	276	4	.	.	PUNCT
fnp-5809	277	1	8	8	X
fnp-5809	277	2	.	.	PUNCT
fnp-5809	277	3	farouk	farouk	PROPN
fnp-5809	277	4	sait	sait	PROPN
fnp-5809	277	5	s	s	PROPN
fnp-5809	277	6	,	,	PUNCT
fnp-5809	277	7	walsh	walsh	PROPN
fnp-5809	277	8	mf	mf	PROPN
fnp-5809	277	9	,	,	PUNCT
fnp-5809	277	10	karajannis	karajannis	PROPN
fnp-5809	277	11	ma	ma	PROPN
fnp-5809	277	12	.	.	PROPN
fnp-5809	278	1	genetic	genetic	ADJ
fnp-5809	278	2	syndromes	syndrome	NOUN
fnp-5809	278	3	predisposing	predispose	VERB
fnp-5809	278	4	to	to	ADP
fnp-5809	278	5	pediatric	pediatric	ADJ
fnp-5809	278	6	brain	brain	NOUN
fnp-5809	278	7	tumors	tumor	NOUN
fnp-5809	278	8	.	.	PUNCT
fnp-5809	279	1	neurooncol	neurooncol	ADJ
fnp-5809	279	2	pract	pract	NOUN
fnp-5809	279	3	.	.	PUNCT
fnp-5809	280	1	2021	2021	NUM
fnp-5809	280	2	feb	feb	NOUN
fnp-5809	280	3	13;8(4):375	13;8(4):375	NUM
fnp-5809	280	4	-	-	SYM
fnp-5809	280	5	390	390	NUM
fnp-5809	280	6	.	.	PUNCT
fnp-5809	281	1	https://doi.org/10.1093/nop/npab012	https://doi.org/10.1093/nop/npab012	PROPN
fnp-5809	281	2	.	.	PUNCT
fnp-5809	282	1	ecollection	ecollection	NOUN
fnp-5809	282	2	2021	2021	NUM
fnp-5809	282	3	aug	aug	PROPN
fnp-5809	282	4	.	.	PUNCT
fnp-5809	283	1	pmid	pmid	NOUN
fnp-5809	283	2	:	:	PUNCT
fnp-5809	283	3	34277017	34277017	NUM
fnp-5809	283	4	.	.	PUNCT
fnp-5809	284	1	9	9	X
fnp-5809	284	2	.	.	X
fnp-5809	284	3	goenaga	goenaga	PROPN
fnp-5809	284	4	j	j	PROPN
fnp-5809	284	5	,	,	PUNCT
fnp-5809	284	6	araque	araque	VERB
fnp-5809	284	7	a	a	PRON
fnp-5809	284	8	,	,	PUNCT
fnp-5809	284	9	kofuji	kofuji	PROPN
fnp-5809	284	10	p	p	X
fnp-5809	284	11	,	,	PUNCT
fnp-5809	284	12	herrera	herrera	PROPN
fnp-5809	284	13	moro	moro	PROPN
fnp-5809	284	14	chao	chao	PROPN
fnp-5809	284	15	d.	d.	PROPN
fnp-5809	284	16	calcium	calcium	PROPN
fnp-5809	284	17	signaling	signal	VERB
fnp-5809	284	18	in	in	ADP
fnp-5809	284	19	astrocytes	astrocyte	NOUN
fnp-5809	284	20	and	and	CCONJ
fnp-5809	284	21	gliotransmitter	gliotransmitter	NOUN
fnp-5809	284	22	release	release	NOUN
fnp-5809	284	23	.	.	PUNCT
fnp-5809	285	1	front	front	ADJ
fnp-5809	285	2	synaptic	synaptic	ADJ
fnp-5809	285	3	neurosci	neurosci	NOUN
fnp-5809	285	4	.	.	PUNCT
fnp-5809	286	1	2023	2023	NUM
fnp-5809	286	2	mar	mar	PROPN
fnp-5809	286	3	2;15:1138577	2;15:1138577	NUM
fnp-5809	286	4	.	.	PUNCT
fnp-5809	287	1	https://doi.org/10.3389/fnsyn.2023.1138577	https://doi.org/10.3389/fnsyn.2023.1138577	NOUN
fnp-5809	287	2	.	.	PUNCT
fnp-5809	288	1	pmid	pmid	NOUN
fnp-5809	288	2	:	:	PUNCT
fnp-5809	288	3	36937570	36937570	NUM
fnp-5809	288	4	.	.	PUNCT
fnp-5809	289	1	10	10	NUM
fnp-5809	289	2	.	.	PUNCT
fnp-5809	289	3	grassl	grassl	PROPN
fnp-5809	289	4	n	n	CCONJ
fnp-5809	289	5	,	,	PUNCT
fnp-5809	289	6	poschke	poschke	NOUN
fnp-5809	289	7	i	i	PRON
fnp-5809	289	8	,	,	PUNCT
fnp-5809	289	9	lindner	lindner	PROPN
fnp-5809	289	10	k	k	PROPN
fnp-5809	289	11	,	,	PUNCT
fnp-5809	289	12	bunse	bunse	NOUN
fnp-5809	289	13	l	l	NOUN
fnp-5809	289	14	,	,	PUNCT
fnp-5809	289	15	mildenberger	mildenberger	NOUN
fnp-5809	289	16	i	i	NOUN
fnp-5809	289	17	,	,	PUNCT
fnp-5809	289	18	boschert	boschert	PROPN
fnp-5809	289	19	t	t	PROPN
fnp-5809	289	20	,	,	PUNCT
fnp-5809	289	21	jähne	jähne	PROPN
fnp-5809	289	22	k	k	PROPN
fnp-5809	289	23	,	,	PUNCT
fnp-5809	289	24	green	green	PROPN
fnp-5809	289	25	ew	ew	PROPN
fnp-5809	289	26	,	,	PUNCT
fnp-5809	289	27	hülsmeyer	hülsmeyer	NOUN
fnp-5809	289	28	i	i	PROPN
fnp-5809	289	29	,	,	PUNCT
fnp-5809	289	30	jünger	jünger	PROPN
fnp-5809	289	31	s	s	PROPN
fnp-5809	289	32	,	,	PUNCT
fnp-5809	289	33	kessler	kessler	PROPN
fnp-5809	289	34	t	t	PROPN
fnp-5809	289	35	,	,	PUNCT
fnp-5809	289	36	suwala	suwala	PROPN
fnp-5809	289	37	ak	ak	PROPN
fnp-5809	289	38	,	,	PUNCT
fnp-5809	289	39	eisele	eisele	PROPN
fnp-5809	289	40	p	p	NOUN
fnp-5809	289	41	,	,	PUNCT
fnp-5809	289	42	breckwoldt	breckwoldt	PROPN
fnp-5809	289	43	mo	mo	PROPN
fnp-5809	289	44	,	,	PUNCT
fnp-5809	289	45	vajkoczy	vajkoczy	NOUN
fnp-5809	289	46	p	p	X
fnp-5809	289	47	,	,	PUNCT
fnp-5809	289	48	grauer	grauer	PROPN
fnp-5809	289	49	om	om	PROPN
fnp-5809	289	50	,	,	PUNCT
fnp-5809	289	51	herrlinger	herrlinger	NOUN
fnp-5809	289	52	u	u	PROPN
fnp-5809	289	53	,	,	PUNCT
fnp-5809	289	54	tonn	tonn	PROPN
fnp-5809	289	55	jc	jc	PROPN
fnp-5809	289	56	,	,	PUNCT
fnp-5809	289	57	denk	denk	PROPN
fnp-5809	289	58	m	m	PROPN
fnp-5809	289	59	,	,	PUNCT
fnp-5809	289	60	sahm	sahm	PROPN
fnp-5809	289	61	f	f	PROPN
fnp-5809	289	62	,	,	PUNCT
fnp-5809	289	63	bendszus	bendszus	PROPN
fnp-5809	289	64	m	m	PROPN
fnp-5809	289	65	,	,	PUNCT
fnp-5809	289	66	von	von	PROPN
fnp-5809	289	67	deimling	deimle	VERB
fnp-5809	289	68	a	a	PRON
fnp-5809	289	69	,	,	PUNCT
fnp-5809	289	70	winkler	winkler	NOUN
fnp-5809	289	71	f	f	PROPN
fnp-5809	289	72	,	,	PUNCT
fnp-5809	289	73	wick	wick	PROPN
fnp-5809	289	74	w	w	PROPN
fnp-5809	289	75	,	,	PUNCT
fnp-5809	289	76	platten	platten	PROPN
fnp-5809	289	77	m	m	PROPN
fnp-5809	289	78	,	,	PUNCT
fnp-5809	289	79	sahm	sahm	PROPN
fnp-5809	289	80	k.	k.	PROPN
fnp-5809	290	1	a	a	DET
fnp-5809	290	2	h3k27m	h3k27m	PROPN
fnp-5809	290	3	-	-	PUNCT
fnp-5809	290	4	targeted	target	VERB
fnp-5809	290	5	vaccine	vaccine	NOUN
fnp-5809	290	6	in	in	ADP
fnp-5809	290	7	adults	adult	NOUN
fnp-5809	290	8	with	with	ADP
fnp-5809	290	9	diffuse	diffuse	ADJ
fnp-5809	290	10	midline	midline	NOUN
fnp-5809	290	11	glioma	glioma	NOUN
fnp-5809	290	12	.	.	PUNCT
fnp-5809	291	1	nat	nat	PROPN
fnp-5809	291	2	med	me	VERB
fnp-5809	291	3	.	.	PUNCT
fnp-5809	292	1	2023	2023	NUM
fnp-5809	292	2	oct;29(10):2586	oct;29(10):2586	X
fnp-5809	292	3	-	-	SYM
fnp-5809	292	4	2592	2592	NUM
fnp-5809	292	5	.	.	PUNCT
fnp-5809	293	1	https://doi.org/10.1038/s41591-023-02555-6	https://doi.org/10.1038/s41591-023-02555-6	PROPN
fnp-5809	293	2	.	.	PUNCT
fnp-5809	294	1	pmid	pmid	NOUN
fnp-5809	294	2	:	:	PUNCT
fnp-5809	294	3	37735561	37735561	NUM
fnp-5809	294	4	.	.	PUNCT
fnp-5809	295	1	11	11	NUM
fnp-5809	295	2	.	.	PUNCT
fnp-5809	296	1	hadad	hadad	PROPN
fnp-5809	296	2	s	s	PROPN
fnp-5809	296	3	,	,	PUNCT
fnp-5809	296	4	gupta	gupta	PROPN
fnp-5809	296	5	r	r	PROPN
fnp-5809	296	6	,	,	PUNCT
fnp-5809	296	7	oberheim	oberheim	PROPN
fnp-5809	296	8	bush	bush	PROPN
fnp-5809	296	9	na	na	PROPN
fnp-5809	296	10	,	,	PUNCT
fnp-5809	296	11	taylor	taylor	PROPN
fnp-5809	296	12	jw	jw	PROPN
fnp-5809	296	13	,	,	PUNCT
fnp-5809	296	14	villanueva	villanueva	PROPN
fnp-5809	296	15	-	-	PROPN
fnp-5809	296	16	meyer	meyer	PROPN
fnp-5809	296	17	je	je	PROPN
fnp-5809	296	18	,	,	PUNCT
fnp-5809	296	19	young	young	PROPN
fnp-5809	296	20	js	js	PROPN
fnp-5809	296	21	,	,	PUNCT
fnp-5809	296	22	wu	wu	PROPN
fnp-5809	296	23	j	j	PROPN
fnp-5809	296	24	,	,	PUNCT
fnp-5809	296	25	ravindranathan	ravindranathan	PROPN
fnp-5809	296	26	a	a	PROPN
fnp-5809	296	27	,	,	PUNCT
fnp-5809	296	28	zhang	zhang	PROPN
fnp-5809	296	29	y	y	PROPN
fnp-5809	296	30	,	,	PUNCT
fnp-5809	296	31	warrier	warrier	PROPN
fnp-5809	296	32	g	g	PROPN
fnp-5809	296	33	,	,	PUNCT
fnp-5809	296	34	mccoy	mccoy	PROPN
fnp-5809	296	35	l	l	PROPN
fnp-5809	296	36	,	,	PUNCT
fnp-5809	296	37	shai	shai	PROPN
fnp-5809	296	38	a	a	PROPN
fnp-5809	296	39	,	,	PUNCT
fnp-5809	296	40	pekmezci	pekmezci	NOUN
fnp-5809	296	41	m	m	PROPN
fnp-5809	296	42	,	,	PUNCT
fnp-5809	296	43	perry	perry	PROPN
fnp-5809	296	44	a	a	PROPN
fnp-5809	296	45	,	,	PUNCT
fnp-5809	296	46	bollen	bollen	PROPN
fnp-5809	296	47	aw	aw	INTJ
fnp-5809	296	48	,	,	PUNCT
fnp-5809	296	49	phillips	phillips	PROPN
fnp-5809	296	50	jj	jj	PROPN
fnp-5809	296	51	,	,	PUNCT
fnp-5809	296	52	braunstein	braunstein	ADV
fnp-5809	296	53	se	se	PROPN
fnp-5809	296	54	,	,	PUNCT
fnp-5809	296	55	raleigh	raleigh	PROPN
fnp-5809	296	56	dr	dr	PROPN
fnp-5809	296	57	,	,	PUNCT
fnp-5809	296	58	theodosopoulos	theodosopoulos	PROPN
fnp-5809	296	59	p	p	PROPN
fnp-5809	296	60	,	,	PUNCT
fnp-5809	296	61	aghi	aghi	PROPN
fnp-5809	296	62	mk	mk	PROPN
fnp-5809	296	63	,	,	PUNCT
fnp-5809	296	64	chang	chang	PROPN
fnp-5809	296	65	ef	ef	PROPN
fnp-5809	296	66	,	,	PUNCT
fnp-5809	296	67	hervey	hervey	NOUN
fnp-5809	296	68	-	-	PUNCT
fnp-5809	296	69	jumper	jumper	NOUN
fnp-5809	296	70	sl	sl	NOUN
fnp-5809	296	71	,	,	PUNCT
fnp-5809	296	72	costello	costello	PROPN
fnp-5809	296	73	jf	jf	PROPN
fnp-5809	296	74	,	,	PUNCT
fnp-5809	296	75	de	de	PROPN
fnp-5809	296	76	groot	groot	PROPN
fnp-5809	296	77	j	j	PROPN
fnp-5809	296	78	,	,	PUNCT
fnp-5809	296	79	butowski	butowski	NOUN
fnp-5809	296	80	na	na	PROPN
fnp-5809	296	81	,	,	PUNCT
fnp-5809	296	82	clarke	clarke	PROPN
fnp-5809	296	83	jl	jl	PROPN
fnp-5809	296	84	,	,	PUNCT
fnp-5809	296	85	chang	chang	PROPN
fnp-5809	296	86	sm	sm	PROPN
fnp-5809	296	87	,	,	PUNCT
fnp-5809	296	88	berger	berger	PROPN
fnp-5809	296	89	ms	ms	PROPN
fnp-5809	296	90	,	,	PUNCT
fnp-5809	296	91	molinaro	molinaro	PROPN
fnp-5809	296	92	am	am	PROPN
fnp-5809	296	93	,	,	PUNCT
fnp-5809	296	94	solomon	solomon	PROPN
fnp-5809	296	95	da	da	PROPN
fnp-5809	296	96	.	.	PUNCT
fnp-5809	297	1	"	"	PUNCT
fnp-5809	297	2	de	de	X
fnp-5809	297	3	novo	novo	NOUN
fnp-5809	297	4	replication	replication	NOUN
fnp-5809	297	5	repair	repair	NOUN
fnp-5809	297	6	deficient	deficient	ADJ
fnp-5809	297	7	glioblastoma	glioblastoma	NOUN
fnp-5809	297	8	,	,	PUNCT
fnp-5809	297	9	idh	idh	NOUN
fnp-5809	297	10	-	-	PUNCT
fnp-5809	297	11	wildtype	wildtype	NOUN
fnp-5809	297	12	"	"	PUNCT
fnp-5809	297	13	is	be	AUX
fnp-5809	297	14	a	a	DET
fnp-5809	297	15	distinct	distinct	ADJ
fnp-5809	297	16	glioblastoma	glioblastoma	NOUN
fnp-5809	297	17	subtype	subtype	NOUN
fnp-5809	297	18	in	in	ADP
fnp-5809	297	19	adults	adult	NOUN
fnp-5809	297	20	that	that	PRON
fnp-5809	297	21	may	may	AUX
fnp-5809	297	22	benefit	benefit	VERB
fnp-5809	297	23	from	from	ADP
fnp-5809	297	24	immune	immune	ADJ
fnp-5809	297	25	checkpoint	checkpoint	NOUN
fnp-5809	297	26	blockade	blockade	NOUN
fnp-5809	297	27	.	.	PUNCT
fnp-5809	298	1	acta	acta	PROPN
fnp-5809	298	2	neuropathol	neuropathol	PROPN
fnp-5809	298	3	.	.	PUNCT
fnp-5809	299	1	2023	2023	NUM
fnp-5809	299	2	dec	dec	PROPN
fnp-5809	299	3	11;147(1):3	11;147(1):3	PROPN
fnp-5809	299	4	.	.	PUNCT
fnp-5809	300	1	https://doi.org/10.1007/s00401-023-02654-1	https://doi.org/10.1007/s00401-023-02654-1	PROPN
fnp-5809	300	2	.	.	PUNCT
fnp-5809	301	1	pmid	pmid	NOUN
fnp-5809	301	2	:	:	PUNCT
fnp-5809	301	3	38079020	38079020	NUM
fnp-5809	301	4	.	.	PUNCT
fnp-5809	302	1	12	12	NUM
fnp-5809	302	2	.	.	PUNCT
fnp-5809	303	1	haskó	haskó	PROPN
fnp-5809	303	2	j	j	PROPN
fnp-5809	303	3	,	,	PUNCT
fnp-5809	303	4	fazakas	fazakas	X
fnp-5809	303	5	c	c	X
fnp-5809	303	6	,	,	PUNCT
fnp-5809	303	7	molnár	molnár	PROPN
fnp-5809	303	8	k	k	PROPN
fnp-5809	303	9	,	,	PUNCT
fnp-5809	303	10	mészáros	mészáros	PROPN
fnp-5809	303	11	á	á	NOUN
fnp-5809	303	12	,	,	PUNCT
fnp-5809	303	13	patai	patai	VERB
fnp-5809	303	14	r	r	NOUN
fnp-5809	303	15	,	,	PUNCT
fnp-5809	303	16	szabó	szabó	VERB
fnp-5809	303	17	g	g	NOUN
fnp-5809	303	18	,	,	PUNCT
fnp-5809	303	19	erdélyi	erdélyi	NOUN
fnp-5809	303	20	f	f	PROPN
fnp-5809	303	21	,	,	PUNCT
fnp-5809	303	22	nyúl	nyúl	NOUN
fnp-5809	303	23	-	-	PUNCT
fnp-5809	303	24	tóth	tóth	NOUN
fnp-5809	303	25	á	á	NOUN
fnp-5809	303	26	,	,	PUNCT
fnp-5809	303	27	győri	győri	PROPN
fnp-5809	303	28	f	f	PROPN
fnp-5809	303	29	,	,	PUNCT
fnp-5809	303	30	kozma	kozma	PROPN
fnp-5809	303	31	m	m	PROPN
fnp-5809	303	32	,	,	PUNCT
fnp-5809	303	33	farkas	farkas	PROPN
fnp-5809	303	34	ae	ae	PROPN
fnp-5809	303	35	,	,	PUNCT
fnp-5809	303	36	krizbai	krizbai	PROPN
fnp-5809	303	37	ia	ia	PROPN
fnp-5809	303	38	,	,	PUNCT
fnp-5809	303	39	wilhelm	wilhelm	PROPN
fnp-5809	303	40	i.	i.	PROPN
fnp-5809	303	41	response	response	NOUN
fnp-5809	303	42	of	of	ADP
fnp-5809	303	43	the	the	DET
fnp-5809	303	44	neurovascular	neurovascular	ADJ
fnp-5809	303	45	unit	unit	NOUN
fnp-5809	303	46	to	to	PART
fnp-5809	303	47	brain	brain	VERB
fnp-5809	303	48	metastatic	metastatic	ADJ
fnp-5809	303	49	breast	breast	NOUN
fnp-5809	303	50	cancer	cancer	NOUN
fnp-5809	303	51	cells	cell	NOUN
fnp-5809	303	52	.	.	PUNCT
fnp-5809	304	1	acta	acta	PROPN
fnp-5809	304	2	neuropathol	neuropathol	PROPN
fnp-5809	304	3	commun	commun	PROPN
fnp-5809	304	4	.	.	PUNCT
fnp-5809	305	1	2019	2019	NUM
fnp-5809	305	2	aug	aug	PROPN
fnp-5809	305	3	19;7(1):133	19;7(1):133	NUM
fnp-5809	305	4	.	.	PUNCT
fnp-5809	305	5	https://doi.org/10.1186/s40478-019-0788-1	https://doi.org/10.1186/s40478-019-0788-1	PROPN
fnp-5809	305	6	.	.	PUNCT
fnp-5809	306	1	pmid	pmid	NOUN
fnp-5809	306	2	:	:	PUNCT
fnp-5809	306	3	31426859	31426859	NUM
fnp-5809	306	4	.	.	PUNCT
fnp-5809	307	1	13	13	NUM
fnp-5809	307	2	.	.	PUNCT
fnp-5809	308	1	hausmann	hausmann	PROPN
fnp-5809	308	2	d	d	PROPN
fnp-5809	308	3	,	,	PUNCT
fnp-5809	308	4	hoffmann	hoffmann	PROPN
fnp-5809	308	5	dc	dc	PROPN
fnp-5809	308	6	,	,	PUNCT
fnp-5809	308	7	venkataramani	venkataramani	PROPN
fnp-5809	308	8	v	v	NOUN
fnp-5809	308	9	,	,	PUNCT
fnp-5809	308	10	jung	jung	PROPN
fnp-5809	308	11	e	e	PROPN
fnp-5809	308	12	,	,	PUNCT
fnp-5809	308	13	horschitz	horschitz	PROPN
fnp-5809	308	14	s	s	PROPN
fnp-5809	308	15	,	,	PUNCT
fnp-5809	308	16	tetzlaff	tetzlaff	PROPN
fnp-5809	308	17	sk	sk	NOUN
fnp-5809	308	18	,	,	PUNCT
fnp-5809	308	19	jabali	jabali	PROPN
fnp-5809	308	20	a	a	PROPN
fnp-5809	308	21	,	,	PUNCT
fnp-5809	308	22	hai	hai	PROPN
fnp-5809	308	23	l	l	PROPN
fnp-5809	308	24	,	,	PUNCT
fnp-5809	308	25	kessler	kessler	PROPN
fnp-5809	308	26	t	t	PROPN
fnp-5809	308	27	,	,	PUNCT
fnp-5809	308	28	azoŕin	azoŕin	PROPN
fnp-5809	308	29	dd	dd	PROPN
fnp-5809	308	30	,	,	PUNCT
fnp-5809	308	31	weil	weil	PROPN
fnp-5809	308	32	s	s	PROPN
fnp-5809	308	33	,	,	PUNCT
fnp-5809	308	34	kourtesakis	kourtesakis	PROPN
fnp-5809	308	35	a	a	PROPN
fnp-5809	308	36	,	,	PUNCT
fnp-5809	308	37	sievers	sievers	PROPN
fnp-5809	308	38	p	p	NOUN
fnp-5809	308	39	,	,	PUNCT
fnp-5809	308	40	habel	habel	NOUN
fnp-5809	308	41	a	a	PRON
fnp-5809	308	42	,	,	PUNCT
fnp-5809	308	43	breckwoldt	breckwoldt	PROPN
fnp-5809	308	44	mo	mo	PROPN
fnp-5809	308	45	,	,	PUNCT
fnp-5809	308	46	karreman	karreman	PROPN
fnp-5809	308	47	ma	ma	PROPN
fnp-5809	308	48	,	,	PUNCT
fnp-5809	308	49	ratliff	ratliff	PROPN
fnp-5809	308	50	m	m	PROPN
fnp-5809	308	51	,	,	PUNCT
fnp-5809	308	52	messmer	messmer	PROPN
fnp-5809	308	53	jm	jm	PROPN
fnp-5809	308	54	,	,	PUNCT
fnp-5809	308	55	yang	yang	PROPN
fnp-5809	308	56	y	y	PROPN
fnp-5809	308	57	,	,	PUNCT
fnp-5809	308	58	reyhan	reyhan	PROPN
fnp-5809	308	59	e	e	PROPN
fnp-5809	308	60	,	,	PUNCT
fnp-5809	308	61	wendler	wendler	PROPN
fnp-5809	308	62	s	s	PROPN
fnp-5809	308	63	,	,	PUNCT
fnp-5809	308	64	löb	löb	PROPN
fnp-5809	308	65	c	c	PROPN
fnp-5809	308	66	,	,	PUNCT
fnp-5809	308	67	mayer	mayer	PROPN
fnp-5809	308	68	c	c	PROPN
fnp-5809	308	69	,	,	PUNCT
fnp-5809	308	70	figarella	figarella	PROPN
fnp-5809	308	71	k	k	NOUN
fnp-5809	308	72	,	,	PUNCT
fnp-5809	308	73	osswald	osswald	PROPN
fnp-5809	308	74	m	m	PROPN
fnp-5809	308	75	,	,	PUNCT
fnp-5809	308	76	solecki	solecki	PROPN
fnp-5809	308	77	g	g	PROPN
fnp-5809	308	78	,	,	PUNCT
fnp-5809	308	79	sahm	sahm	PROPN
fnp-5809	308	80	f	f	PROPN
fnp-5809	308	81	,	,	PUNCT
fnp-5809	308	82	garaschuk	garaschuk	VERB
fnp-5809	308	83	o	o	NOUN
fnp-5809	308	84	,	,	PUNCT
fnp-5809	308	85	kuner	kuner	PROPN
fnp-5809	308	86	t	t	PROPN
fnp-5809	308	87	,	,	PUNCT
fnp-5809	308	88	koch	koch	PROPN
fnp-5809	308	89	p	p	PROPN
fnp-5809	308	90	,	,	PUNCT
fnp-5809	308	91	schlesner	schlesner	PROPN
fnp-5809	308	92	m	m	PROPN
fnp-5809	308	93	,	,	PUNCT
fnp-5809	308	94	wick	wick	PROPN
fnp-5809	308	95	w	w	PROPN
fnp-5809	308	96	,	,	PUNCT
fnp-5809	308	97	winkler	winkler	PROPN
fnp-5809	308	98	f.	f.	PROPN
fnp-5809	308	99	autonomous	autonomous	PROPN
fnp-5809	308	100	rhythmic	rhythmic	ADJ
fnp-5809	308	101	activity	activity	NOUN
fnp-5809	308	102	in	in	ADP
fnp-5809	308	103	glioma	glioma	NOUN
fnp-5809	308	104	networks	network	NOUN
fnp-5809	308	105	drives	drive	VERB
fnp-5809	308	106	brain	brain	VERB
fnp-5809	308	107	tumour	tumour	NOUN
fnp-5809	308	108	growth	growth	NOUN
fnp-5809	308	109	.	.	PUNCT
fnp-5809	309	1	nature	nature	NOUN
fnp-5809	309	2	.	.	PUNCT
fnp-5809	310	1	2023	2023	NUM
fnp-5809	310	2	jan;613(7942):179	jan;613(7942):179	NOUN
fnp-5809	310	3	-	-	PUNCT
fnp-5809	310	4	186	186	NUM
fnp-5809	310	5	.	.	PUNCT
fnp-5809	311	1	https://doi.org/10.1038/s41586-022-05520-4	https://doi.org/10.1038/s41586-022-05520-4	NUM
fnp-5809	311	2	.	.	PUNCT
fnp-5809	312	1	pmid	pmid	NOUN
fnp-5809	312	2	:	:	PUNCT
fnp-5809	312	3	36517594	36517594	NUM
fnp-5809	312	4	14	14	NUM
fnp-5809	312	5	.	.	PUNCT
fnp-5809	313	1	izraely	izraely	PROPN
fnp-5809	313	2	s	s	PROPN
fnp-5809	313	3	,	,	PUNCT
fnp-5809	313	4	ben	ben	PROPN
fnp-5809	313	5	-	-	PROPN
fnp-5809	313	6	menachem	menachem	PROPN
fnp-5809	313	7	s	s	PROPN
fnp-5809	313	8	,	,	PUNCT
fnp-5809	313	9	malka	malka	PROPN
fnp-5809	313	10	s	s	PROPN
fnp-5809	313	11	,	,	PUNCT
fnp-5809	313	12	sagi	sagi	PROPN
fnp-5809	313	13	-	-	PUNCT
fnp-5809	313	14	assif	assif	PROPN
fnp-5809	313	15	o	o	PROPN
fnp-5809	313	16	,	,	PUNCT
fnp-5809	313	17	bustos	bustos	PROPN
fnp-5809	313	18	ma	ma	PROPN
fnp-5809	313	19	,	,	PUNCT
fnp-5809	313	20	adir	adir	PROPN
fnp-5809	313	21	o	o	PROPN
fnp-5809	313	22	,	,	PUNCT
fnp-5809	313	23	meshel	meshel	PROPN
fnp-5809	313	24	t	t	PROPN
fnp-5809	313	25	,	,	PUNCT
fnp-5809	313	26	chelladurai	chelladurai	PROPN
fnp-5809	313	27	m	m	PROPN
fnp-5809	313	28	,	,	PUNCT
fnp-5809	313	29	ryu	ryu	PROPN
fnp-5809	313	30	s	s	PROPN
fnp-5809	313	31	,	,	PUNCT
fnp-5809	313	32	ramos	ramos	PROPN
fnp-5809	313	33	ri	ri	PROPN
fnp-5809	313	34	,	,	PUNCT
fnp-5809	313	35	pasmanik	pasmanik	VERB
fnp-5809	313	36	-	-	NOUN
fnp-5809	313	37	chor	chor	NOUN
fnp-5809	313	38	m	m	PROPN
fnp-5809	313	39	,	,	PUNCT
fnp-5809	313	40	hoon	hoon	PROPN
fnp-5809	313	41	dsb	dsb	PROPN
fnp-5809	313	42	,	,	PUNCT
fnp-5809	313	43	witz	witz	PROPN
fnp-5809	313	44	ip.the	ip.the	DET
fnp-5809	313	45	vicious	vicious	ADJ
fnp-5809	313	46	cycle	cycle	NOUN
fnp-5809	313	47	of	of	ADP
fnp-5809	313	48	melanoma	melanoma	ADJ
fnp-5809	313	49	-	-	PUNCT
fnp-5809	313	50	microglia	microglia	ADJ
fnp-5809	313	51	crosstalk	crosstalk	NOUN
fnp-5809	313	52	:	:	PUNCT
fnp-5809	313	53	inter	inter	ADJ
fnp-5809	313	54	-	-	ADJ
fnp-5809	313	55	melanoma	melanoma	ADJ
fnp-5809	313	56	variations	variation	NOUN
fnp-5809	313	57	in	in	ADP
fnp-5809	313	58	the	the	DET
fnp-5809	313	59	brain	brain	NOUN
fnp-5809	313	60	-	-	PUNCT
fnp-5809	313	61	metastasis	metastasis	NOUN
fnp-5809	313	62	-	-	PUNCT
fnp-5809	313	63	promoting	promote	VERB
fnp-5809	313	64	il-6	il-6	NOUN
fnp-5809	313	65	/	/	SYM
fnp-5809	313	66	jak	jak	PROPN
fnp-5809	313	67	/	/	SYM
fnp-5809	313	68	stat3	stat3	NOUN
fnp-5809	313	69	signaling	signal	VERB
fnp-5809	313	70	pathway	pathway	NOUN
fnp-5809	313	71	.	.	PUNCT
fnp-5809	314	1	cells	cell	NOUN
fnp-5809	314	2	.	.	PUNCT
fnp-5809	315	1	2023	2023	NUM
fnp-5809	315	2	may	may	AUX
fnp-5809	315	3	30;12(11):1513	30;12(11):1513	NUM
fnp-5809	315	4	.	.	PUNCT
fnp-5809	316	1	https://doi.org/10.3390/cells12111513	https://doi.org/10.3390/cells12111513	PROPN
fnp-5809	316	2	.	.	PUNCT
fnp-5809	317	1	pmid	pmid	NOUN
fnp-5809	317	2	:	:	PUNCT
fnp-5809	317	3	37296634	37296634	NUM
fnp-5809	317	4	.	.	PUNCT
fnp-5809	318	1	15	15	NUM
fnp-5809	318	2	.	.	PUNCT
fnp-5809	319	1	karreman	karreman	PROPN
fnp-5809	319	2	ma	ma	PROPN
fnp-5809	319	3	,	,	PUNCT
fnp-5809	319	4	bauer	bauer	PROPN
fnp-5809	319	5	at	at	ADP
fnp-5809	319	6	,	,	PUNCT
fnp-5809	319	7	solecki	solecki	PROPN
fnp-5809	319	8	g	g	PROPN
fnp-5809	319	9	,	,	PUNCT
fnp-5809	319	10	berghoff	berghoff	INTJ
fnp-5809	319	11	as	as	ADP
fnp-5809	319	12	,	,	PUNCT
fnp-5809	319	13	mayer	mayer	PROPN
fnp-5809	319	14	cd	cd	PROPN
fnp-5809	319	15	,	,	PUNCT
fnp-5809	319	16	frey	frey	PROPN
fnp-5809	319	17	k	k	PROPN
fnp-5809	319	18	,	,	PUNCT
fnp-5809	319	19	hebach	hebach	PROPN
fnp-5809	319	20	n	n	CCONJ
fnp-5809	319	21	,	,	PUNCT
fnp-5809	319	22	feinauer	feinauer	PROPN
fnp-5809	319	23	mj	mj	PROPN
fnp-5809	319	24	,	,	PUNCT
fnp-5809	319	25	schieber	schieber	PROPN
fnp-5809	319	26	nl	nl	PROPN
fnp-5809	319	27	,	,	PUNCT
fnp-5809	319	28	tehranian	tehranian	PROPN
fnp-5809	319	29	c	c	NOUN
fnp-5809	319	30	,	,	PUNCT
fnp-5809	319	31	mercier	merci	ADJ
fnp-5809	319	32	l	l	NOUN
fnp-5809	319	33	,	,	PUNCT
fnp-5809	319	34	singhal	singhal	PROPN
fnp-5809	319	35	m	m	PROPN
fnp-5809	319	36	,	,	PUNCT
fnp-5809	319	37	venkataramani	venkataramani	PROPN
fnp-5809	319	38	v	v	NOUN
fnp-5809	319	39	,	,	PUNCT
fnp-5809	319	40	schubert	schubert	PROPN
fnp-5809	319	41	mc	mc	PROPN
fnp-5809	319	42	,	,	PUNCT
fnp-5809	319	43	hinze	hinze	PROPN
fnp-5809	319	44	d	d	PROPN
fnp-5809	319	45	,	,	PUNCT
fnp-5809	319	46	hölzel	hölzel	PROPN
fnp-5809	319	47	m	m	NOUN
fnp-5809	319	48	,	,	PUNCT
fnp-5809	319	49	helfrich	helfrich	SCONJ
fnp-5809	319	50	i	i	PRON
fnp-5809	319	51	,	,	PUNCT
fnp-5809	319	52	schadendorf	schadendorf	PROPN
fnp-5809	319	53	d	d	PROPN
fnp-5809	319	54	,	,	PUNCT
fnp-5809	319	55	schneider	schneider	PROPN
fnp-5809	319	56	sw	sw	PROPN
fnp-5809	319	57	,	,	PUNCT
fnp-5809	319	58	westphal	westphal	PROPN
fnp-5809	319	59	d	d	PROPN
fnp-5809	319	60	,	,	PUNCT
fnp-5809	319	61	augustin	augustin	PROPN
fnp-5809	319	62	hg	hg	PROPN
fnp-5809	319	63	,	,	PUNCT
fnp-5809	319	64	goetz	goetz	PROPN
fnp-5809	319	65	jg	jg	PROPN
fnp-5809	319	66	,	,	PUNCT
fnp-5809	319	67	schwab	schwab	PROPN
fnp-5809	319	68	y	y	PROPN
fnp-5809	319	69	,	,	PUNCT
fnp-5809	319	70	wick	wick	PROPN
fnp-5809	319	71	w	w	PROPN
fnp-5809	319	72	,	,	PUNCT
fnp-5809	319	73	winkler	winkler	PROPN
fnp-5809	319	74	f.	f.	PROPN
fnp-5809	319	75	active	active	ADJ
fnp-5809	319	76	remodeling	remodeling	NOUN
fnp-5809	319	77	of	of	ADP
fnp-5809	319	78	capillary	capillary	ADJ
fnp-5809	319	79	endothelium	endothelium	NOUN
fnp-5809	319	80	via	via	ADP
fnp-5809	319	81	cancer	cancer	NOUN
fnp-5809	319	82	cell	cell	NOUN
fnp-5809	319	83	-	-	PUNCT
fnp-5809	319	84	derived	derive	VERB
fnp-5809	319	85	mmp9	mmp9	NOUN
fnp-5809	319	86	promotes	promote	VERB
fnp-5809	319	87	metastatic	metastatic	ADJ
fnp-5809	319	88	brain	brain	NOUN
fnp-5809	319	89	colonization	colonization	NOUN
fnp-5809	319	90	.	.	PUNCT
fnp-5809	320	1	cancer	cancer	NOUN
fnp-5809	320	2	res	re	NOUN
fnp-5809	320	3	.	.	PUNCT
fnp-5809	321	1	2023	2023	NUM
fnp-5809	321	2	apr	apr	NOUN
fnp-5809	321	3	14;83(8):1299	14;83(8):1299	NUM
fnp-5809	321	4	-	-	SYM
fnp-5809	321	5	1314	1314	NUM
fnp-5809	321	6	.	.	PUNCT
fnp-5809	322	1	https://doi.org/10.1158/0008-5472.can-22-3964	https://doi.org/10.1158/0008-5472.can-22-3964	X
fnp-5809	322	2	.	.	PUNCT
fnp-5809	323	1	pmid	pmid	NOUN
fnp-5809	323	2	:	:	PUNCT
fnp-5809	323	3	36652557	36652557	NUM
fnp-5809	323	4	.	.	PUNCT
fnp-5809	324	1	16	16	NUM
fnp-5809	324	2	.	.	PUNCT
fnp-5809	325	1	konteatis	konteatis	PROPN
fnp-5809	325	2	z	z	PROPN
fnp-5809	325	3	,	,	PUNCT
fnp-5809	325	4	artin	artin	PROPN
fnp-5809	325	5	e	e	PROPN
fnp-5809	325	6	,	,	PUNCT
fnp-5809	325	7	nicolay	nicolay	PROPN
fnp-5809	325	8	b	b	PROPN
fnp-5809	325	9	,	,	PUNCT
fnp-5809	325	10	straley	straley	PROPN
fnp-5809	325	11	k	k	PROPN
fnp-5809	325	12	,	,	PUNCT
fnp-5809	325	13	padyana	padyana	PROPN
fnp-5809	325	14	ak	ak	PROPN
fnp-5809	325	15	,	,	PUNCT
fnp-5809	325	16	jin	jin	PROPN
fnp-5809	325	17	l	l	PROPN
fnp-5809	325	18	,	,	PUNCT
fnp-5809	325	19	chen	chen	PROPN
fnp-5809	325	20	y	y	PROPN
fnp-5809	325	21	,	,	PUNCT
fnp-5809	325	22	narayaraswamy	narayaraswamy	NOUN
fnp-5809	325	23	r	r	NOUN
fnp-5809	325	24	,	,	PUNCT
fnp-5809	325	25	tong	tong	PROPN
fnp-5809	325	26	s	s	PROPN
fnp-5809	325	27	,	,	PUNCT
fnp-5809	325	28	wang	wang	PROPN
fnp-5809	325	29	f	f	PROPN
fnp-5809	325	30	,	,	PUNCT
fnp-5809	325	31	zhou	zhou	PROPN
fnp-5809	325	32	d	d	PROPN
fnp-5809	325	33	,	,	PUNCT
fnp-5809	325	34	cui	cui	PROPN
fnp-5809	325	35	d	d	PROPN
fnp-5809	325	36	,	,	PUNCT
fnp-5809	325	37	cai	cai	PROPN
fnp-5809	326	1	z	z	PROPN
fnp-5809	326	2	,	,	PUNCT
fnp-5809	326	3	luo	luo	PROPN
fnp-5809	326	4	z	z	PROPN
fnp-5809	326	5	,	,	PUNCT
fnp-5809	326	6	fang	fang	PROPN
fnp-5809	326	7	c	c	PROPN
fnp-5809	326	8	,	,	PUNCT
fnp-5809	326	9	tang	tang	PROPN
fnp-5809	326	10	h	h	NOUN
fnp-5809	326	11	,	,	PUNCT
fnp-5809	326	12	lv	lv	PROPN
fnp-5809	326	13	x	x	PROPN
fnp-5809	326	14	,	,	PUNCT
fnp-5809	326	15	nagaraja	nagaraja	PROPN
fnp-5809	326	16	r	r	PROPN
fnp-5809	326	17	,	,	PUNCT
fnp-5809	326	18	yang	yang	PROPN
fnp-5809	326	19	h	h	PROPN
fnp-5809	326	20	,	,	PUNCT
fnp-5809	326	21	su	su	PROPN
fnp-5809	326	22	sm	sm	PROPN
fnp-5809	326	23	,	,	PUNCT
fnp-5809	326	24	sui	sui	PROPN
fnp-5809	326	25	z	z	PROPN
fnp-5809	326	26	,	,	PUNCT
fnp-5809	326	27	dang	dang	PROPN
fnp-5809	326	28	l	l	NOUN
fnp-5809	326	29	,	,	PUNCT
fnp-5809	326	30	yen	yen	PROPN
fnp-5809	326	31	k	k	NOUN
fnp-5809	326	32	,	,	PUNCT
fnp-5809	326	33	popovici	popovici	ADJ
fnp-5809	326	34	-	-	PUNCT
fnp-5809	326	35	muller	muller	PROPN
fnp-5809	326	36	j	j	PROPN
fnp-5809	326	37	,	,	PUNCT
fnp-5809	326	38	codega	codega	PROPN
fnp-5809	326	39	p	p	PROPN
fnp-5809	326	40	,	,	PUNCT
fnp-5809	326	41	campos	campos	PROPN
fnp-5809	326	42	c	c	PROPN
fnp-5809	326	43	,	,	PUNCT
fnp-5809	326	44	mellinghoff	mellinghoff	PROPN
fnp-5809	326	45	ik	ik	PROPN
fnp-5809	326	46	,	,	PUNCT
fnp-5809	326	47	biller	biller	PROPN
fnp-5809	326	48	sa	sa	PROPN
fnp-5809	326	49	.	.	PUNCT
fnp-5809	327	1	vorasidenib	vorasidenib	PROPN
fnp-5809	327	2	(	(	PUNCT
fnp-5809	327	3	ag-881	ag-881	PROPN
fnp-5809	327	4	):	):	PUNCT
fnp-5809	327	5	a	a	DET
fnp-5809	327	6	first	first	ADJ
fnp-5809	327	7	-	-	PUNCT
fnp-5809	327	8	in	in	ADP
fnp-5809	327	9	-	-	PUNCT
fnp-5809	327	10	class	class	NOUN
fnp-5809	327	11	,	,	PUNCT
fnp-5809	327	12	brain	brain	NOUN
fnp-5809	327	13	-	-	PUNCT
fnp-5809	327	14	penetrant	penetrant	NOUN
fnp-5809	327	15	dual	dual	ADJ
fnp-5809	327	16	inhibitor	inhibitor	NOUN
fnp-5809	327	17	of	of	ADP
fnp-5809	327	18	mutant	mutant	ADJ
fnp-5809	327	19	idh1	idh1	NOUN
fnp-5809	327	20	and	and	CCONJ
fnp-5809	327	21	2	2	NUM
fnp-5809	327	22	for	for	ADP
fnp-5809	327	23	treatment	treatment	NOUN
fnp-5809	327	24	of	of	ADP
fnp-5809	327	25	glioma	glioma	NOUN
fnp-5809	327	26	.	.	PUNCT
fnp-5809	328	1	acs	acs	PROPN
fnp-5809	328	2	med	med	PROPN
fnp-5809	328	3	chem	chem	PROPN
fnp-5809	328	4	lett	lett	PROPN
fnp-5809	328	5	.	.	PUNCT
fnp-5809	329	1	2020	2020	NUM
fnp-5809	329	2	jan	jan	PROPN
fnp-5809	329	3	22;11(2):101	22;11(2):101	NUM
fnp-5809	329	4	-	-	PUNCT
fnp-5809	329	5	107	107	NUM
fnp-5809	329	6	.	.	PUNCT
fnp-5809	330	1	https://doi.org/10.1021/acsmedchemlett.9b00509	https://doi.org/10.1021/acsmedchemlett.9b00509	INTJ
fnp-5809	330	2	.	.	PUNCT
fnp-5809	331	1	pmid	pmid	NOUN
fnp-5809	331	2	:	:	PUNCT
fnp-5809	331	3	32071674	32071674	NUM
fnp-5809	331	4	.	.	PUNCT
fnp-5809	332	1	17	17	NUM
fnp-5809	332	2	.	.	PUNCT
fnp-5809	333	1	lopez	lopez	ADJ
fnp-5809	333	2	-	-	PUNCT
fnp-5809	333	3	navarro	navarro	PROPN
fnp-5809	333	4	er	er	INTJ
fnp-5809	333	5	,	,	PUNCT
fnp-5809	333	6	gutierrez	gutierrez	PROPN
fnp-5809	333	7	j.	j.	PROPN
fnp-5809	333	8	metalloproteinases	metalloproteinases	PROPN
fnp-5809	333	9	and	and	CCONJ
fnp-5809	333	10	their	their	PRON
fnp-5809	333	11	inhibitors	inhibitor	NOUN
fnp-5809	333	12	in	in	ADP
fnp-5809	333	13	neurological	neurological	ADJ
fnp-5809	333	14	disease	disease	NOUN
fnp-5809	333	15	.	.	PUNCT
fnp-5809	334	1	naunyn	naunyn	PROPN
fnp-5809	334	2	schmiedebergs	schmiedebergs	PROPN
fnp-5809	334	3	arch	arch	NOUN
fnp-5809	334	4	pharmacol	pharmacol	PROPN
fnp-5809	334	5	.	.	PUNCT
fnp-5809	335	1	2022	2022	NUM
fnp-5809	335	2	jan;395(1):27	jan;395(1):27	PROPN
fnp-5809	335	3	-	-	PUNCT
fnp-5809	335	4	38	38	NUM
fnp-5809	335	5	.	.	PUNCT
fnp-5809	336	1	https://doi.org/10.1007/s00210-021-02188-x	https://doi.org/10.1007/s00210-021-02188-x	PROPN
fnp-5809	336	2	.	.	PUNCT
fnp-5809	337	1	pmid	pmid	NOUN
fnp-5809	337	2	:	:	PUNCT
fnp-5809	337	3	34851449	34851449	NUM
fnp-5809	337	4	.	.	PUNCT
fnp-5809	338	1	18	18	NUM
fnp-5809	338	2	.	.	X
fnp-5809	338	3	mellinghoff	mellinghoff	PROPN
fnp-5809	338	4	ik	ik	PROPN
fnp-5809	338	5	,	,	PUNCT
fnp-5809	338	6	van	van	PROPN
fnp-5809	338	7	den	den	PROPN
fnp-5809	338	8	bent	bent	ADJ
fnp-5809	338	9	mj	mj	NOUN
fnp-5809	338	10	,	,	PUNCT
fnp-5809	338	11	blumenthal	blumenthal	PROPN
fnp-5809	338	12	dt	dt	PROPN
fnp-5809	338	13	,	,	PUNCT
fnp-5809	338	14	touat	touat	PROPN
fnp-5809	338	15	m	m	PROPN
fnp-5809	338	16	,	,	PUNCT
fnp-5809	338	17	peters	peters	PROPN
fnp-5809	338	18	kb	kb	PROPN
fnp-5809	338	19	,	,	PUNCT
fnp-5809	338	20	clarke	clarke	PROPN
fnp-5809	338	21	j	j	PROPN
fnp-5809	338	22	,	,	PUNCT
fnp-5809	338	23	mendez	mendez	PROPN
fnp-5809	338	24	j	j	PROPN
fnp-5809	338	25	,	,	PUNCT
fnp-5809	338	26	yust	yust	PROPN
fnp-5809	338	27	-	-	PUNCT
fnp-5809	338	28	katz	katz	PROPN
fnp-5809	338	29	s	s	PROPN
fnp-5809	338	30	,	,	PUNCT
fnp-5809	338	31	welsh	welsh	PROPN
fnp-5809	338	32	l	l	PROPN
fnp-5809	338	33	,	,	PUNCT
fnp-5809	338	34	mason	mason	PROPN
fnp-5809	338	35	wp	wp	PROPN
fnp-5809	338	36	,	,	PUNCT
fnp-5809	338	37	ducray	ducray	NOUN
fnp-5809	338	38	f	f	PROPN
fnp-5809	338	39	,	,	PUNCT
fnp-5809	338	40	umemura	umemura	PROPN
fnp-5809	338	41	y	y	PROPN
fnp-5809	338	42	,	,	PUNCT
fnp-5809	338	43	nabors	nabors	PROPN
fnp-5809	338	44	b	b	PROPN
fnp-5809	338	45	,	,	PUNCT
fnp-5809	338	46	holdhoff	holdhoff	NOUN
fnp-5809	338	47	m	m	PROPN
fnp-5809	338	48	,	,	PUNCT
fnp-5809	338	49	hottinger	hottinger	PROPN
fnp-5809	338	50	af	af	PROPN
fnp-5809	338	51	,	,	PUNCT
fnp-5809	338	52	arakawa	arakawa	PROPN
fnp-5809	338	53	y	y	PROPN
fnp-5809	338	54	,	,	PUNCT
fnp-5809	338	55	sepulveda	sepulveda	PROPN
fnp-5809	338	56	jm	jm	PROPN
fnp-5809	338	57	,	,	PUNCT
fnp-5809	338	58	wick	wick	PROPN
fnp-5809	338	59	w	w	PROPN
fnp-5809	338	60	,	,	PUNCT
fnp-5809	338	61	soffietti	soffietti	ADJ
fnp-5809	338	62	r	r	NOUN
fnp-5809	338	63	,	,	PUNCT
fnp-5809	338	64	perry	perry	PROPN
fnp-5809	338	65	jr	jr	PROPN
fnp-5809	338	66	,	,	PUNCT
fnp-5809	338	67	giglio	giglio	PROPN
fnp-5809	338	68	p	p	PROPN
fnp-5809	338	69	,	,	PUNCT
fnp-5809	338	70	de	de	X
fnp-5809	338	71	la	la	X
fnp-5809	338	72	fuente	fuente	PROPN
fnp-5809	338	73	m	m	PROPN
fnp-5809	338	74	,	,	PUNCT
fnp-5809	338	75	maher	maher	PROPN
fnp-5809	338	76	ea	ea	PROPN
fnp-5809	338	77	,	,	PUNCT
fnp-5809	338	78	schoenfeld	schoenfeld	PROPN
fnp-5809	338	79	s	s	PROPN
fnp-5809	338	80	,	,	PUNCT
fnp-5809	338	81	zhao	zhao	PROPN
fnp-5809	338	82	d	d	PROPN
fnp-5809	338	83	,	,	PUNCT
fnp-5809	338	84	pandya	pandya	PROPN
fnp-5809	338	85	ss	ss	PROPN
fnp-5809	338	86	,	,	PUNCT
fnp-5809	338	87	steelman	steelman	PROPN
fnp-5809	338	88	l	l	PROPN
fnp-5809	338	89	,	,	PUNCT
fnp-5809	338	90	hassan	hassan	PROPN
fnp-5809	338	91	i	i	PRON
fnp-5809	338	92	,	,	PUNCT
fnp-5809	338	93	wen	wen	PROPN
fnp-5809	338	94	py	py	PROPN
fnp-5809	338	95	,	,	PUNCT
fnp-5809	338	96	cloughesy	cloughesy	VERB
fnp-5809	338	97	tf	tf	X
fnp-5809	338	98	;	;	PUNCT
fnp-5809	338	99	indigo	indigo	NOUN
fnp-5809	338	100	trial	trial	NOUN
fnp-5809	338	101	investigators	investigator	NOUN
fnp-5809	338	102	.	.	PUNCT
fnp-5809	339	1	vorasidenib	vorasidenib	NOUN
fnp-5809	339	2	in	in	ADP
fnp-5809	339	3	idh1or	idh1or	PROPN
fnp-5809	339	4	idh2	idh2	NOUN
fnp-5809	339	5	-	-	PUNCT
fnp-5809	339	6	mutant	mutant	ADJ
fnp-5809	339	7	low	low	ADJ
fnp-5809	339	8	-	-	PUNCT
fnp-5809	339	9	grade	grade	NOUN
fnp-5809	339	10	glioma	glioma	NOUN
fnp-5809	339	11	.	.	PUNCT
fnp-5809	340	1	n	n	CCONJ
fnp-5809	340	2	engl	engl	PROPN
fnp-5809	340	3	j	j	PROPN
fnp-5809	340	4	med	med	PROPN
fnp-5809	340	5	.	.	PUNCT
fnp-5809	341	1	2023	2023	NUM
fnp-5809	341	2	aug	aug	PROPN
fnp-5809	341	3	17;389(7):589	17;389(7):589	NUM
fnp-5809	341	4	-	-	PUNCT
fnp-5809	341	5	601	601	NUM
fnp-5809	341	6	.	.	PUNCT
fnp-5809	342	1	https://doi.org/10.1056/nejmoa2304194	https://doi.org/10.1056/nejmoa2304194	NOUN
fnp-5809	342	2	.	.	PUNCT
fnp-5809	343	1	pmid	pmid	NOUN
fnp-5809	343	2	:	:	PUNCT
fnp-5809	343	3	37272516	37272516	NUM
fnp-5809	343	4	.	.	PUNCT
fnp-5809	344	1	19	19	NUM
fnp-5809	344	2	.	.	X
fnp-5809	344	3	mittelbronn	mittelbronn	PROPN
fnp-5809	344	4	m.	m.	PROPN
fnp-5809	344	5	neurooncology	neurooncology	PROPN
fnp-5809	344	6	:	:	PUNCT
fnp-5809	344	7	2023	2023	NUM
fnp-5809	344	8	update	update	NOUN
fnp-5809	344	9	.	.	PUNCT
fnp-5809	345	1	free	free	ADJ
fnp-5809	345	2	neuropathol	neuropathol	NOUN
fnp-5809	345	3	.	.	PUNCT
fnp-5809	346	1	2023	2023	NUM
fnp-5809	346	2	mar	mar	PROPN
fnp-5809	346	3	20;4:4	20;4:4	NUM
fnp-5809	346	4	-	-	PUNCT
fnp-5809	346	5	4	4	NUM
fnp-5809	346	6	.	.	PUNCT
fnp-5809	347	1	https://doi.org/10.17879/freeneuropathology-2023-4692	https://doi.org/10.17879/freeneuropathology-2023-4692	PROPN
fnp-5809	347	2	.	.	PUNCT
fnp-5809	347	3	pmid	pmid	PROPN
fnp-5809	347	4	:	:	PUNCT
fnp-5809	347	5	37283935	37283935	NUM
fnp-5809	347	6	.	.	PUNCT
fnp-5809	348	1	20	20	NUM
fnp-5809	348	2	.	.	PUNCT
fnp-5809	348	3	ochs	ochs	PROPN
fnp-5809	348	4	k	k	PROPN
fnp-5809	348	5	,	,	PUNCT
fnp-5809	348	6	ott	ott	PROPN
fnp-5809	348	7	m	m	PROPN
fnp-5809	348	8	,	,	PUNCT
fnp-5809	348	9	bunse	bunse	PROPN
fnp-5809	348	10	t	t	PROPN
fnp-5809	348	11	,	,	PUNCT
fnp-5809	348	12	sahm	sahm	PROPN
fnp-5809	348	13	f	f	PROPN
fnp-5809	348	14	,	,	PUNCT
fnp-5809	348	15	bunse	bunse	NOUN
fnp-5809	348	16	l	l	NOUN
fnp-5809	348	17	,	,	PUNCT
fnp-5809	348	18	deumelandt	deumelandt	PROPN
fnp-5809	348	19	k	k	NOUN
fnp-5809	348	20	,	,	PUNCT
fnp-5809	348	21	sonner	sonner	PROPN
fnp-5809	348	22	jk	jk	PROPN
fnp-5809	348	23	,	,	PUNCT
fnp-5809	348	24	keil	keil	PROPN
fnp-5809	348	25	m	m	PROPN
fnp-5809	348	26	,	,	PUNCT
fnp-5809	348	27	von	von	PROPN
fnp-5809	348	28	deimling	deimle	VERB
fnp-5809	348	29	a	a	PRON
fnp-5809	348	30	,	,	PUNCT
fnp-5809	348	31	wick	wick	PROPN
fnp-5809	348	32	w	w	PROPN
fnp-5809	348	33	,	,	PUNCT
fnp-5809	348	34	platten	platten	PROPN
fnp-5809	348	35	m.	m.	NOUN
fnp-5809	348	36	k27m	k27m	NOUN
fnp-5809	348	37	-	-	NOUN
fnp-5809	348	38	mutant	mutant	ADJ
fnp-5809	348	39	histone-3	histone-3	NOUN
fnp-5809	348	40	as	as	ADP
fnp-5809	348	41	a	a	DET
fnp-5809	348	42	novel	novel	ADJ
fnp-5809	348	43	target	target	NOUN
fnp-5809	348	44	for	for	ADP
fnp-5809	348	45	glioma	glioma	ADJ
fnp-5809	348	46	immunotherapy	immunotherapy	NOUN
fnp-5809	348	47	.	.	PUNCT
fnp-5809	349	1	oncoimmunology	oncoimmunology	NOUN
fnp-5809	349	2	.	.	PUNCT
fnp-5809	350	1	2017	2017	NUM
fnp-5809	350	2	may	may	PROPN
fnp-5809	350	3	12;6(7):e1328340	12;6(7):e1328340	NUM
fnp-5809	350	4	.	.	PUNCT
fnp-5809	351	1	https://doi.org/10.1080/2162402x.2017.1328340	https://doi.org/10.1080/2162402x.2017.1328340	X
fnp-5809	351	2	.	.	PUNCT
fnp-5809	352	1	pmid	pmid	NOUN
fnp-5809	352	2	:	:	PUNCT
fnp-5809	352	3	28811969	28811969	NUM
fnp-5809	352	4	.	.	PUNCT
fnp-5809	353	1	21	21	NUM
fnp-5809	353	2	.	.	PUNCT
fnp-5809	354	1	pukrop	pukrop	PROPN
fnp-5809	354	2	t	t	PROPN
fnp-5809	354	3	,	,	PUNCT
fnp-5809	354	4	dehghani	dehghani	PROPN
fnp-5809	354	5	f	f	PROPN
fnp-5809	354	6	,	,	PUNCT
fnp-5809	354	7	chuang	chuang	PROPN
fnp-5809	354	8	hn	hn	PROPN
fnp-5809	354	9	,	,	PUNCT
fnp-5809	354	10	lohaus	lohaus	ADJ
fnp-5809	354	11	r	r	NOUN
fnp-5809	354	12	,	,	PUNCT
fnp-5809	354	13	bayanga	bayanga	ADV
fnp-5809	354	14	k	k	NOUN
fnp-5809	354	15	,	,	PUNCT
fnp-5809	354	16	heermann	heermann	PROPN
fnp-5809	354	17	s	s	PART
fnp-5809	354	18	,	,	PUNCT
fnp-5809	354	19	regen	regen	PROPN
fnp-5809	354	20	t	t	PROPN
fnp-5809	354	21	,	,	PUNCT
fnp-5809	354	22	van	van	PROPN
fnp-5809	354	23	rossum	rossum	PROPN
fnp-5809	355	1	d	d	PROPN
fnp-5809	355	2	,	,	PUNCT
fnp-5809	355	3	klemm	klemm	NOUN
fnp-5809	355	4	f	f	PROPN
fnp-5809	355	5	,	,	PUNCT
fnp-5809	355	6	schulz	schulz	PROPN
fnp-5809	355	7	m	m	PROPN
fnp-5809	355	8	,	,	PUNCT
fnp-5809	355	9	siam	siam	PROPN
fnp-5809	355	10	l	l	NOUN
fnp-5809	355	11	,	,	PUNCT
fnp-5809	355	12	hoffmann	hoffmann	PROPN
fnp-5809	355	13	a	a	DET
fnp-5809	355	14	,	,	PUNCT
fnp-5809	355	15	trümper	trümper	NOUN
fnp-5809	355	16	l	l	NOUN
fnp-5809	355	17	,	,	PUNCT
fnp-5809	355	18	stadelmann	stadelmann	PROPN
fnp-5809	355	19	c	c	PROPN
fnp-5809	355	20	,	,	PUNCT
fnp-5809	355	21	bechmann	bechmann	PROPN
fnp-5809	355	22	i	i	PRON
fnp-5809	355	23	,	,	PUNCT
fnp-5809	355	24	hanisch	hanisch	PROPN
fnp-5809	355	25	uk	uk	PROPN
fnp-5809	355	26	,	,	PUNCT
fnp-5809	355	27	binder	binder	NOUN
fnp-5809	355	28	c.	c.	PROPN
fnp-5809	355	29	microglia	microglia	PROPN
fnp-5809	355	30	promote	promote	VERB
fnp-5809	355	31	colonization	colonization	NOUN
fnp-5809	355	32	of	of	ADP
fnp-5809	355	33	brain	brain	NOUN
fnp-5809	355	34	tissue	tissue	NOUN
fnp-5809	355	35	by	by	ADP
fnp-5809	355	36	breast	breast	NOUN
fnp-5809	355	37	cancer	cancer	NOUN
fnp-5809	355	38	cells	cell	NOUN
fnp-5809	355	39	in	in	ADP
fnp-5809	355	40	a	a	DET
fnp-5809	355	41	wnt	wnt	NOUN
fnp-5809	355	42	-	-	PUNCT
fnp-5809	355	43	dependent	dependent	ADJ
fnp-5809	355	44	way	way	NOUN
fnp-5809	355	45	.	.	PUNCT
fnp-5809	356	1	glia	glia	NOUN
fnp-5809	356	2	.	.	PUNCT
fnp-5809	357	1	2010	2010	NUM
fnp-5809	357	2	sep;58(12):1477	sep;58(12):1477	NOUN
fnp-5809	357	3	-	-	PUNCT
fnp-5809	357	4	89	89	NUM
fnp-5809	357	5	.	.	PUNCT
fnp-5809	357	6	https://doi.org/10.1002/glia.21022	https://doi.org/10.1002/glia.21022	NOUN
fnp-5809	357	7	.	.	PUNCT
fnp-5809	358	1	pmid	pmid	NOUN
fnp-5809	358	2	:	:	PUNCT
fnp-5809	358	3	20549749	20549749	NUM
fnp-5809	358	4	.	.	PUNCT
fnp-5809	359	1	22	22	NUM
fnp-5809	359	2	.	.	PUNCT
fnp-5809	360	1	renovanz	renovanz	PROPN
fnp-5809	360	2	m	m	PROPN
fnp-5809	360	3	,	,	PUNCT
fnp-5809	360	4	kurz	kurz	PROPN
fnp-5809	360	5	sc	sc	PROPN
fnp-5809	360	6	,	,	PUNCT
fnp-5809	360	7	rieger	rieger	PROPN
fnp-5809	360	8	j	j	PROPN
fnp-5809	360	9	,	,	PUNCT
fnp-5809	360	10	walter	walter	PROPN
fnp-5809	360	11	b	b	PROPN
fnp-5809	360	12	,	,	PUNCT
fnp-5809	360	13	becker	becker	PROPN
fnp-5809	360	14	h	h	PROPN
fnp-5809	360	15	,	,	PUNCT
fnp-5809	360	16	hille	hille	PROPN
fnp-5809	360	17	h	h	PROPN
fnp-5809	360	18	,	,	PUNCT
fnp-5809	360	19	bombach	bombach	VERB
fnp-5809	360	20	p	p	NOUN
fnp-5809	360	21	,	,	PUNCT
fnp-5809	360	22	rieger	rieger	PROPN
fnp-5809	360	23	d	d	PROPN
fnp-5809	360	24	,	,	PUNCT
fnp-5809	360	25	grosse	grosse	PROPN
fnp-5809	360	26	l	l	NOUN
fnp-5809	360	27	,	,	PUNCT
fnp-5809	360	28	häusser	häusser	PROPN
fnp-5809	360	29	l	l	NOUN
fnp-5809	360	30	,	,	PUNCT
fnp-5809	360	31	skardelly	skardelly	ADV
fnp-5809	360	32	m	m	PROPN
fnp-5809	360	33	,	,	PUNCT
fnp-5809	360	34	merk	merk	PROPN
fnp-5809	360	35	dj	dj	PROPN
fnp-5809	360	36	,	,	PUNCT
fnp-5809	360	37	paulsen	paulsen	PROPN
fnp-5809	360	38	f	f	PROPN
fnp-5809	360	39	,	,	PUNCT
fnp-5809	360	40	hoffmann	hoffmann	PROPN
fnp-5809	360	41	e	e	PROPN
fnp-5809	360	42	,	,	PUNCT
fnp-5809	360	43	gani	gani	PROPN
fnp-5809	360	44	c	c	PROPN
fnp-5809	360	45	,	,	PUNCT
fnp-5809	360	46	neumann	neumann	PROPN
fnp-5809	360	47	m	m	PROPN
fnp-5809	360	48	,	,	PUNCT
fnp-5809	360	49	beschorner	beschorner	ADP
fnp-5809	360	50	r	r	NOUN
fnp-5809	360	51	,	,	PUNCT
fnp-5809	360	52	rieß	rieß	NOUN
fnp-5809	360	53	o	o	NOUN
fnp-5809	360	54	,	,	PUNCT
fnp-5809	360	55	roggia	roggia	ADJ
fnp-5809	360	56	c	c	PROPN
fnp-5809	360	57	,	,	PUNCT
fnp-5809	360	58	schroeder	schroeder	PROPN
fnp-5809	360	59	c	c	PROPN
fnp-5809	360	60	,	,	PUNCT
fnp-5809	360	61	ossowski	ossowski	PROPN
fnp-5809	360	62	s	s	PROPN
fnp-5809	360	63	,	,	PUNCT
fnp-5809	360	64	armeanu	armeanu	NOUN
fnp-5809	360	65	-	-	PUNCT
fnp-5809	360	66	ebinger	ebinger	NOUN
fnp-5809	360	67	s	s	PROPN
fnp-5809	360	68	,	,	PUNCT
fnp-5809	360	69	gschwind	gschwind	NOUN
fnp-5809	360	70	a	a	PRON
fnp-5809	360	71	,	,	PUNCT
fnp-5809	360	72	biskup	biskup	NOUN
fnp-5809	360	73	s	s	PROPN
fnp-5809	360	74	,	,	PUNCT
fnp-5809	360	75	schulze	schulze	NOUN
fnp-5809	360	76	m	m	PROPN
fnp-5809	360	77	,	,	PUNCT
fnp-5809	360	78	fend	fend	VERB
fnp-5809	360	79	f	f	PROPN
fnp-5809	360	80	,	,	PUNCT
fnp-5809	360	81	singer	singer	NOUN
fnp-5809	360	82	s	s	PROPN
fnp-5809	360	83	,	,	PUNCT
fnp-5809	360	84	zender	zender	PROPN
fnp-5809	360	85	l	l	PROPN
fnp-5809	360	86	,	,	PUNCT
fnp-5809	360	87	lengerke	lengerke	PROPN
fnp-5809	360	88	c	c	PROPN
fnp-5809	360	89	,	,	PUNCT
fnp-5809	360	90	brucker	brucker	PROPN
fnp-5809	360	91	sy	sy	PROPN
fnp-5809	360	92	,	,	PUNCT
fnp-5809	360	93	engler	engler	PROPN
fnp-5809	360	94	t	t	PROPN
fnp-5809	360	95	,	,	PUNCT
fnp-5809	360	96	forschner	forschner	PROPN
fnp-5809	360	97	a	a	NOUN
fnp-5809	360	98	,	,	PUNCT
fnp-5809	360	99	stenzl	stenzl	NOUN
fnp-5809	360	100	a	a	PRON
fnp-5809	360	101	,	,	PUNCT
fnp-5809	360	102	kohlbacher	kohlbacher	ADJ
fnp-5809	360	103	o	o	NOUN
fnp-5809	360	104	,	,	PUNCT
fnp-5809	360	105	nahnsen	nahnsen	PROPN
fnp-5809	360	106	s	s	PART
fnp-5809	360	107	,	,	PUNCT
fnp-5809	360	108	gabernet	gabernet	ADJ
fnp-5809	360	109	g	g	NOUN
fnp-5809	360	110	,	,	PUNCT
fnp-5809	360	111	fillinger	fillinger	NOUN
fnp-5809	360	112	s	s	PROPN
fnp-5809	360	113	,	,	PUNCT
fnp-5809	360	114	bender	bender	PROPN
fnp-5809	360	115	b	b	NOUN
fnp-5809	360	116	,	,	PUNCT
fnp-5809	360	117	ernemann	ernemann	PROPN
fnp-5809	360	118	u	u	NOUN
fnp-5809	360	119	,	,	PUNCT
fnp-5809	360	120	öner	öner	ADV
fnp-5809	360	121	ö	ö	NOUN
fnp-5809	360	122	,	,	PUNCT
fnp-5809	360	123	beha	beha	PROPN
fnp-5809	360	124	j	j	PROPN
fnp-5809	360	125	,	,	PUNCT
fnp-5809	360	126	malek	malek	PROPN
fnp-5809	360	127	hs	hs	PROPN
fnp-5809	360	128	,	,	PUNCT
fnp-5809	360	129	möller	möller	NOUN
fnp-5809	360	130	y	y	PROPN
fnp-5809	360	131	,	,	PUNCT
fnp-5809	360	132	ruhm	ruhm	PROPN
fnp-5809	360	133	k	k	PROPN
fnp-5809	360	134	,	,	PUNCT
fnp-5809	360	135	tatagiba	tatagiba	PROPN
fnp-5809	360	136	m	m	PROPN
fnp-5809	360	137	,	,	PUNCT
fnp-5809	360	138	schittenhelm	schittenhelm	PROPN
fnp-5809	360	139	j	j	PROPN
fnp-5809	360	140	,	,	PUNCT
fnp-5809	360	141	bitzer	bitzer	PROPN
fnp-5809	360	142	m	m	PROPN
fnp-5809	360	143	,	,	PUNCT
fnp-5809	360	144	malek	malek	PROPN
fnp-5809	360	145	n	n	CCONJ
fnp-5809	360	146	,	,	PUNCT
fnp-5809	360	147	zips	zips	PROPN
fnp-5809	360	148	d	d	PROPN
fnp-5809	360	149	,	,	PUNCT
fnp-5809	360	150	tabatabai	tabatabai	NOUN
fnp-5809	360	151	g.	g.	PROPN
fnp-5809	360	152	clinical	clinical	PROPN
fnp-5809	360	153	outcome	outcome	NOUN
fnp-5809	360	154	of	of	ADP
fnp-5809	360	155	biomarker	biomarker	NOUN
fnp-5809	360	156	-	-	PUNCT
fnp-5809	360	157	guided	guide	VERB
fnp-5809	360	158	therapies	therapy	NOUN
fnp-5809	360	159	in	in	ADP
fnp-5809	360	160	adult	adult	NOUN
fnp-5809	360	161	patients	patient	NOUN
fnp-5809	360	162	with	with	ADP
fnp-5809	360	163	tumors	tumor	NOUN
fnp-5809	360	164	of	of	ADP
fnp-5809	360	165	the	the	DET
fnp-5809	360	166	nervous	nervous	ADJ
fnp-5809	360	167	system	system	NOUN
fnp-5809	360	168	.	.	PUNCT
fnp-5809	361	1	neurooncol	neurooncol	PROPN
fnp-5809	361	2	adv	adv	PROPN
fnp-5809	361	3	.	.	PROPN
fnp-5809	362	1	2023	2023	NUM
fnp-5809	362	2	feb	feb	PROPN
fnp-5809	362	3	14;5(1):vdad012	14;5(1):vdad012	PROPN
fnp-5809	362	4	.	.	PUNCT
fnp-5809	362	5	https://doi.org/10.1093/noajnl/vdad012	https://doi.org/10.1093/noajnl/vdad012	PROPN
fnp-5809	362	6	.	.	PUNCT
fnp-5809	363	1	pmid	pmid	NOUN
fnp-5809	363	2	:	:	PUNCT
fnp-5809	363	3	36915613	36915613	NUM
fnp-5809	363	4	.	.	PUNCT
fnp-5809	364	1	23	23	NUM
fnp-5809	364	2	.	.	PUNCT
fnp-5809	365	1	rodgers	rodger	VERB
fnp-5809	365	2	lt	lt	PROPN
fnp-5809	365	3	,	,	PUNCT
fnp-5809	365	4	villano	villano	PROPN
fnp-5809	365	5	jl	jl	PROPN
fnp-5809	365	6	,	,	PUNCT
fnp-5809	365	7	hartz	hartz	PROPN
fnp-5809	365	8	ams	ams	PROPN
fnp-5809	365	9	,	,	PUNCT
fnp-5809	365	10	bauer	bauer	PROPN
fnp-5809	365	11	b.	b.	PROPN
fnp-5809	365	12	glioblastoma	glioblastoma	PROPN
fnp-5809	365	13	standard	standard	NOUN
fnp-5809	365	14	of	of	ADP
fnp-5809	365	15	care	care	NOUN
fnp-5809	365	16	:	:	PUNCT
fnp-5809	365	17	effects	effect	NOUN
fnp-5809	365	18	on	on	ADP
fnp-5809	365	19	tumor	tumor	NOUN
fnp-5809	365	20	evolution	evolution	NOUN
fnp-5809	365	21	and	and	CCONJ
fnp-5809	365	22	reverse	reverse	ADJ
fnp-5809	365	23	translation	translation	NOUN
fnp-5809	365	24	in	in	ADP
fnp-5809	365	25	preclinical	preclinical	ADJ
fnp-5809	365	26	models	model	NOUN
fnp-5809	365	27	.	.	PUNCT
fnp-5809	366	1	cancers	cancer	NOUN
fnp-5809	366	2	(	(	PUNCT
fnp-5809	366	3	basel	basel	PROPN
fnp-5809	366	4	)	)	PUNCT
fnp-5809	366	5	.	.	PUNCT
fnp-5809	367	1	2024	2024	NUM
fnp-5809	367	2	jul	jul	PROPN
fnp-5809	367	3	24;16(15):2638	24;16(15):2638	NUM
fnp-5809	367	4	.	.	PUNCT
fnp-5809	368	1	https://doi.org/10.3390/cancers16152638	https://doi.org/10.3390/cancers16152638	PROPN
fnp-5809	368	2	.	.	PUNCT
fnp-5809	369	1	pmid	pmid	NOUN
fnp-5809	369	2	:	:	PUNCT
fnp-5809	369	3	39123366	39123366	NUM
fnp-5809	369	4	.	.	PUNCT
fnp-5809	370	1	24	24	NUM
fnp-5809	370	2	.	.	PUNCT
fnp-5809	371	1	shibao	shibao	PROPN
fnp-5809	371	2	s	s	PROPN
fnp-5809	371	3	,	,	PUNCT
fnp-5809	371	4	minami	minami	PROPN
fnp-5809	371	5	n	n	PROPN
fnp-5809	371	6	,	,	PUNCT
fnp-5809	371	7	koike	koike	PROPN
fnp-5809	371	8	n	n	CCONJ
fnp-5809	371	9	,	,	PUNCT
fnp-5809	371	10	fukui	fukui	PROPN
fnp-5809	371	11	n	n	CCONJ
fnp-5809	371	12	,	,	PUNCT
fnp-5809	371	13	yoshida	yoshida	PROPN
fnp-5809	371	14	k	k	PROPN
fnp-5809	371	15	,	,	PUNCT
fnp-5809	371	16	saya	saya	PROPN
fnp-5809	371	17	h	h	PROPN
fnp-5809	371	18	,	,	PUNCT
fnp-5809	371	19	sampetrean	sampetrean	ADJ
fnp-5809	371	20	o.	o.	PROPN
fnp-5809	371	21	metabolic	metabolic	PROPN
fnp-5809	371	22	heterogeneity	heterogeneity	NOUN
fnp-5809	371	23	and	and	CCONJ
fnp-5809	371	24	plasticity	plasticity	NOUN
fnp-5809	371	25	of	of	ADP
fnp-5809	371	26	glioma	glioma	NOUN
fnp-5809	371	27	stem	stem	NOUN
fnp-5809	371	28	cells	cell	NOUN
fnp-5809	371	29	in	in	ADP
fnp-5809	371	30	a	a	DET
fnp-5809	371	31	mouse	mouse	NOUN
fnp-5809	371	32	glioblastoma	glioblastoma	NOUN
fnp-5809	371	33	model	model	NOUN
fnp-5809	371	34	.	.	PUNCT
fnp-5809	372	1	neuro	neuro	PROPN
fnp-5809	372	2	oncol	oncol	PROPN
fnp-5809	372	3	.	.	PUNCT
fnp-5809	373	1	2018	2018	NUM
fnp-5809	373	2	feb	feb	NOUN
fnp-5809	373	3	19;20(3):343	19;20(3):343	NUM
fnp-5809	373	4	-	-	SYM
fnp-5809	373	5	354	354	NUM
fnp-5809	373	6	.	.	PUNCT
fnp-5809	373	7	https://doi.org/10.1093/neuonc/nox170	https://doi.org/10.1093/neuonc/nox170	PROPN
fnp-5809	373	8	.	.	PUNCT
fnp-5809	374	1	pmid	pmid	NOUN
fnp-5809	374	2	:	:	PUNCT
fnp-5809	374	3	29016888	29016888	NUM
fnp-5809	374	4	.	.	PUNCT
fnp-5809	375	1	25	25	NUM
fnp-5809	375	2	.	.	PUNCT
fnp-5809	375	3	sturm	sturm	PROPN
fnp-5809	375	4	d	d	PROPN
fnp-5809	375	5	,	,	PUNCT
fnp-5809	375	6	capper	capper	NOUN
fnp-5809	375	7	d	d	NOUN
fnp-5809	375	8	,	,	PUNCT
fnp-5809	375	9	andreiuolo	andreiuolo	PROPN
fnp-5809	375	10	f	f	PROPN
fnp-5809	375	11	,	,	PUNCT
fnp-5809	375	12	gessi	gessi	PROPN
fnp-5809	375	13	m	m	PROPN
fnp-5809	375	14	,	,	PUNCT
fnp-5809	375	15	kölsche	kölsche	PROPN
fnp-5809	375	16	c	c	PROPN
fnp-5809	375	17	,	,	PUNCT
fnp-5809	375	18	reinhardt	reinhardt	PROPN
fnp-5809	375	19	a	a	PROPN
fnp-5809	375	20	,	,	PUNCT
fnp-5809	375	21	sievers	sievers	PROPN
fnp-5809	375	22	p	p	PROPN
fnp-5809	375	23	,	,	PUNCT
fnp-5809	375	24	wefers	wefers	PROPN
fnp-5809	375	25	ak	ak	PROPN
fnp-5809	375	26	,	,	PUNCT
fnp-5809	375	27	ebrahimi	ebrahimi	PROPN
fnp-5809	375	28	a	a	X
fnp-5809	375	29	,	,	PUNCT
fnp-5809	375	30	suwala	suwala	PROPN
fnp-5809	375	31	ak	ak	PROPN
fnp-5809	375	32	,	,	PUNCT
fnp-5809	375	33	gielen	gielen	PROPN
fnp-5809	375	34	gh	gh	PROPN
fnp-5809	375	35	,	,	PUNCT
fnp-5809	375	36	sill	sill	NOUN
fnp-5809	375	37	m	m	PROPN
fnp-5809	375	38	,	,	PUNCT
fnp-5809	375	39	schrimpf	schrimpf	NOUN
fnp-5809	375	40	d	d	PROPN
fnp-5809	375	41	,	,	PUNCT
fnp-5809	375	42	stichel	stichel	PROPN
fnp-5809	375	43	d	d	PROPN
fnp-5809	375	44	,	,	PUNCT
fnp-5809	375	45	hovestadt	hovestadt	ADJ
fnp-5809	375	46	v	v	NOUN
fnp-5809	375	47	,	,	PUNCT
fnp-5809	375	48	daenekas	daenekas	PROPN
fnp-5809	375	49	b	b	AUX
fnp-5809	375	50	,	,	PUNCT
fnp-5809	375	51	rode	ride	VERB
fnp-5809	375	52	a	a	DET
fnp-5809	375	53	,	,	PUNCT
fnp-5809	375	54	hamelmann	hamelmann	PROPN
fnp-5809	375	55	s	s	NOUN
fnp-5809	375	56	,	,	PUNCT
fnp-5809	375	57	previti	previti	NOUN
fnp-5809	375	58	c	c	NOUN
fnp-5809	375	59	,	,	PUNCT
fnp-5809	375	60	jäger	jäger	PROPN
fnp-5809	375	61	n	n	PROPN
fnp-5809	375	62	,	,	PUNCT
fnp-5809	375	63	buchhalter	buchhalter	PROPN
fnp-5809	375	64	i	i	PROPN
fnp-5809	375	65	,	,	PUNCT
fnp-5809	375	66	blattner	blattner	NOUN
fnp-5809	375	67	-	-	PUNCT
fnp-5809	375	68	johnson	johnson	PROPN
fnp-5809	375	69	m	m	PROPN
fnp-5809	375	70	,	,	PUNCT
fnp-5809	375	71	jones	jones	PROPN
fnp-5809	375	72	bc	bc	PROPN
fnp-5809	375	73	,	,	PUNCT
fnp-5809	375	74	warmuth	warmuth	NOUN
fnp-5809	375	75	-	-	PUNCT
fnp-5809	375	76	metz	metz	PROPN
fnp-5809	375	77	m	m	PROPN
fnp-5809	375	78	,	,	PUNCT
fnp-5809	375	79	bison	bison	PROPN
fnp-5809	375	80	b	b	PROPN
fnp-5809	375	81	,	,	PUNCT
fnp-5809	375	82	grund	grund	PROPN
fnp-5809	375	83	k	k	NOUN
fnp-5809	375	84	,	,	PUNCT
fnp-5809	375	85	sutter	sutter	PROPN
fnp-5809	375	86	c	c	PROPN
fnp-5809	375	87	,	,	PUNCT
fnp-5809	375	88	hirsch	hirsch	PROPN
fnp-5809	375	89	s	s	PROPN
fnp-5809	375	90	,	,	PUNCT
fnp-5809	375	91	dikow	dikow	PROPN
fnp-5809	375	92	n	n	CCONJ
fnp-5809	375	93	,	,	PUNCT
fnp-5809	375	94	hasselblatt	hasselblatt	PROPN
fnp-5809	375	95	m	m	PROPN
fnp-5809	375	96	,	,	PUNCT
fnp-5809	375	97	schüller	schüller	ADJ
fnp-5809	375	98	u	u	NOUN
fnp-5809	375	99	,	,	PUNCT
fnp-5809	375	100	koch	koch	PROPN
fnp-5809	375	101	a	a	X
fnp-5809	375	102	,	,	PUNCT
fnp-5809	375	103	gerber	gerber	PROPN
fnp-5809	375	104	nu	nu	PROPN
fnp-5809	375	105	,	,	PUNCT
fnp-5809	375	106	white	white	ADJ
fnp-5809	375	107	cl	cl	NOUN
fnp-5809	375	108	,	,	PUNCT
fnp-5809	375	109	buntine	buntine	PROPN
fnp-5809	375	110	mk	mk	PROPN
fnp-5809	375	111	,	,	PUNCT
fnp-5809	375	112	kinross	kinross	PROPN
fnp-5809	375	113	k	k	PROPN
fnp-5809	375	114	,	,	PUNCT
fnp-5809	375	115	algar	algar	PROPN
fnp-5809	375	116	em	em	PRON
fnp-5809	375	117	,	,	PUNCT
fnp-5809	375	118	hansford	hansford	PROPN
fnp-5809	375	119	jr	jr	PROPN
fnp-5809	375	120	,	,	PUNCT
fnp-5809	375	121	gottardo	gottardo	PROPN
fnp-5809	375	122	ng	ng	PROPN
fnp-5809	375	123	,	,	PUNCT
fnp-5809	375	124	schuhmann	schuhmann	PROPN
fnp-5809	375	125	mu	mu	PROPN
fnp-5809	375	126	,	,	PUNCT
fnp-5809	375	127	thomale	thomale	NOUN
fnp-5809	375	128	uw	uw	PROPN
fnp-5809	375	129	,	,	PUNCT
fnp-5809	375	130	hernáiz	hernáiz	NOUN
fnp-5809	375	131	driever	driever	NOUN
fnp-5809	375	132	p	p	PROPN
fnp-5809	375	133	,	,	PUNCT
fnp-5809	375	134	gnekow	gnekow	ADV
fnp-5809	375	135	a	a	PRON
fnp-5809	375	136	,	,	PUNCT
fnp-5809	375	137	witt	witt	PROPN
fnp-5809	375	138	o	o	NOUN
fnp-5809	375	139	,	,	PUNCT
fnp-5809	375	140	müller	müller	PROPN
fnp-5809	375	141	hl	hl	PROPN
fnp-5809	375	142	,	,	PUNCT
fnp-5809	375	143	calaminus	calaminus	NOUN
fnp-5809	375	144	g	g	NOUN
fnp-5809	375	145	,	,	PUNCT
fnp-5809	375	146	fleischhack	fleischhack	VERB
fnp-5809	375	147	g	g	NOUN
fnp-5809	375	148	,	,	PUNCT
fnp-5809	375	149	kordes	kordes	PROPN
fnp-5809	375	150	u	u	NOUN
fnp-5809	375	151	,	,	PUNCT
fnp-5809	375	152	mynarek	mynarek	PROPN
fnp-5809	375	153	m	m	PROPN
fnp-5809	375	154	,	,	PUNCT
fnp-5809	375	155	rutkowski	rutkowski	PROPN
fnp-5809	375	156	s	s	PROPN
fnp-5809	375	157	,	,	PUNCT
fnp-5809	375	158	frühwald	frühwald	PROPN
fnp-5809	375	159	mc	mc	PROPN
fnp-5809	375	160	,	,	PUNCT
fnp-5809	375	161	kramm	kramm	PROPN
fnp-5809	375	162	cm	cm	PROPN
fnp-5809	375	163	,	,	PUNCT
fnp-5809	375	164	von	von	PROPN
fnp-5809	375	165	deimling	deimle	VERB
fnp-5809	375	166	a	a	PRON
fnp-5809	375	167	,	,	PUNCT
fnp-5809	375	168	pietsch	pietsch	PROPN
fnp-5809	375	169	t	t	PROPN
fnp-5809	375	170	,	,	PUNCT
fnp-5809	375	171	sahm	sahm	PROPN
fnp-5809	375	172	f	f	PROPN
fnp-5809	375	173	,	,	PUNCT
fnp-5809	375	174	pfister	pfister	PROPN
fnp-5809	375	175	sm	sm	PROPN
fnp-5809	375	176	,	,	PUNCT
fnp-5809	375	177	jones	jones	PROPN
fnp-5809	376	1	dtw	dtw	PROPN
fnp-5809	376	2	.	.	PUNCT
fnp-5809	376	3	multiomic	multiomic	PROPN
fnp-5809	376	4	neuropathology	neuropathology	NOUN
fnp-5809	376	5	improves	improve	VERB
fnp-5809	376	6	diagnostic	diagnostic	ADJ
fnp-5809	376	7	accuracy	accuracy	NOUN
fnp-5809	376	8	in	in	ADP
fnp-5809	376	9	pediatric	pediatric	ADJ
fnp-5809	376	10	neuro	neuro	NOUN
fnp-5809	376	11	-	-	PUNCT
fnp-5809	376	12	oncology	oncology	NOUN
fnp-5809	376	13	.	.	PUNCT
fnp-5809	377	1	nat	nat	PROPN
fnp-5809	377	2	med	me	VERB
fnp-5809	377	3	.	.	PUNCT
fnp-5809	378	1	2023	2023	NUM
fnp-5809	378	2	apr;29(4):917	apr;29(4):917	NUM
fnp-5809	378	3	-	-	PUNCT
fnp-5809	378	4	926	926	NUM
fnp-5809	378	5	.	.	PUNCT
fnp-5809	379	1	https://doi.org/10.1038/s41591-023-02255-1	https://doi.org/10.1038/s41591-023-02255-1	PROPN
fnp-5809	379	2	.	.	PUNCT
fnp-5809	380	1	pmid	pmid	NOUN
fnp-5809	380	2	:	:	PUNCT
fnp-5809	380	3	36928815	36928815	NUM
fnp-5809	380	4	.	.	PUNCT
fnp-5809	381	1	26	26	NUM
fnp-5809	381	2	.	.	PUNCT
fnp-5809	381	3	turner	turner	PROPN
fnp-5809	381	4	kl	kl	PROPN
fnp-5809	381	5	,	,	PUNCT
fnp-5809	381	6	honasoge	honasoge	PROPN
fnp-5809	381	7	a	a	PROPN
fnp-5809	381	8	,	,	PUNCT
fnp-5809	381	9	robert	robert	PROPN
fnp-5809	381	10	sm	sm	PROPN
fnp-5809	381	11	,	,	PUNCT
fnp-5809	381	12	mcferrin	mcferrin	NOUN
fnp-5809	381	13	mm	mm	PROPN
fnp-5809	381	14	,	,	PUNCT
fnp-5809	381	15	sontheimer	sontheimer	PROPN
fnp-5809	381	16	h.	h.	PROPN
fnp-5809	381	17	a	a	DET
fnp-5809	381	18	proinvasive	proinvasive	ADJ
fnp-5809	381	19	role	role	NOUN
fnp-5809	381	20	for	for	ADP
fnp-5809	381	21	the	the	DET
fnp-5809	381	22	ca(2	ca(2	NOUN
fnp-5809	381	23	+	+	NOUN
fnp-5809	381	24	)	)	PUNCT
fnp-5809	381	25	-activated	-activated	ADJ
fnp-5809	381	26	k(+	k(+	ADJ
fnp-5809	381	27	)	)	PUNCT
fnp-5809	381	28	channel	channel	NOUN
fnp-5809	381	29	kca3.1	kca3.1	PROPN
fnp-5809	381	30	in	in	ADP
fnp-5809	381	31	malignant	malignant	ADJ
fnp-5809	381	32	glioma	glioma	NOUN
fnp-5809	381	33	.	.	PUNCT
fnp-5809	382	1	glia	glia	PROPN
fnp-5809	382	2	.	.	PUNCT
fnp-5809	383	1	2014	2014	NUM
fnp-5809	384	1	jun;62(6):971	jun;62(6):971	PROPN
fnp-5809	384	2	-	-	PUNCT
fnp-5809	384	3	81	81	NUM
fnp-5809	384	4	.	.	PUNCT
fnp-5809	385	1	https://doi.org/10.1002/glia.22655	https://doi.org/10.1002/glia.22655	NOUN
fnp-5809	385	2	.	.	PUNCT
fnp-5809	386	1	pmid	pmid	NOUN
fnp-5809	386	2	:	:	PUNCT
fnp-5809	386	3	24585442	24585442	NUM
fnp-5809	386	4	.	.	PUNCT
fnp-5809	387	1	27	27	NUM
fnp-5809	387	2	.	.	PUNCT
fnp-5809	388	1	valdebenito	valdebenito	PROPN
fnp-5809	388	2	s	s	PROPN
fnp-5809	388	3	,	,	PUNCT
fnp-5809	388	4	malik	malik	PROPN
fnp-5809	388	5	s	s	PROPN
fnp-5809	388	6	,	,	PUNCT
fnp-5809	388	7	luu	luu	PROPN
fnp-5809	388	8	r	r	PROPN
fnp-5809	388	9	,	,	PUNCT
fnp-5809	388	10	loudig	loudig	PROPN
fnp-5809	388	11	o	o	NOUN
fnp-5809	388	12	,	,	PUNCT
fnp-5809	388	13	mitchell	mitchell	PROPN
fnp-5809	388	14	m	m	PROPN
fnp-5809	388	15	,	,	PUNCT
fnp-5809	388	16	okafo	okafo	VERB
fnp-5809	388	17	g	g	PROPN
fnp-5809	388	18	,	,	PUNCT
fnp-5809	388	19	bhat	bhat	PROPN
fnp-5809	388	20	k	k	PROPN
fnp-5809	388	21	,	,	PUNCT
fnp-5809	388	22	prideaux	prideaux	PROPN
fnp-5809	388	23	b	b	NUM
fnp-5809	388	24	,	,	PUNCT
fnp-5809	388	25	eugenin	eugenin	PROPN
fnp-5809	388	26	ea	ea	PROPN
fnp-5809	388	27	.	.	PUNCT
fnp-5809	389	1	tunneling	tunneling	NOUN
fnp-5809	389	2	nanotubes	nanotube	NOUN
fnp-5809	389	3	,	,	PUNCT
fnp-5809	389	4	tnt	tnt	PROPN
fnp-5809	389	5	,	,	PUNCT
fnp-5809	389	6	communicate	communicate	VERB
fnp-5809	389	7	glioblastoma	glioblastoma	NOUN
fnp-5809	389	8	with	with	ADP
fnp-5809	389	9	surrounding	surround	VERB
fnp-5809	389	10	non	non	ADJ
fnp-5809	389	11	-	-	ADJ
fnp-5809	389	12	tumor	tumor	ADJ
fnp-5809	389	13	astrocytes	astrocyte	NOUN
fnp-5809	389	14	to	to	PART
fnp-5809	389	15	adapt	adapt	VERB
fnp-5809	389	16	them	they	PRON
fnp-5809	389	17	to	to	ADP
fnp-5809	389	18	hypoxic	hypoxic	ADJ
fnp-5809	389	19	and	and	CCONJ
fnp-5809	389	20	metabolic	metabolic	ADJ
fnp-5809	389	21	tumor	tumor	NOUN
fnp-5809	389	22	conditions	condition	NOUN
fnp-5809	389	23	.	.	PUNCT
fnp-5809	390	1	sci	sci	PROPN
fnp-5809	390	2	rep	rep	PROPN
fnp-5809	390	3	.	.	PROPN
fnp-5809	390	4	2021	2021	NUM
fnp-5809	390	5	jul	jul	PROPN
fnp-5809	390	6	15;11(1):14556	15;11(1):14556	NUM
fnp-5809	390	7	.	.	PUNCT
fnp-5809	391	1	https://doi.org/10.1038/s41598-021-93775-8	https://doi.org/10.1038/s41598-021-93775-8	PROPN
fnp-5809	391	2	.	.	PUNCT
fnp-5809	392	1	pmid	pmid	NOUN
fnp-5809	392	2	:	:	PUNCT
fnp-5809	392	3	34267246	34267246	NUM
fnp-5809	392	4	.	.	PUNCT
fnp-5809	393	1	28	28	NUM
fnp-5809	393	2	.	.	X
fnp-5809	393	3	varešlija	varešlija	PROPN
fnp-5809	393	4	d	d	PROPN
fnp-5809	393	5	,	,	PUNCT
fnp-5809	393	6	priedigkeit	priedigkeit	PROPN
fnp-5809	393	7	n	n	NUM
fnp-5809	393	8	,	,	PUNCT
fnp-5809	393	9	fagan	fagan	VERB
fnp-5809	393	10	a	a	PRON
fnp-5809	393	11	,	,	PUNCT
fnp-5809	393	12	purcell	purcell	PROPN
fnp-5809	393	13	s	s	PROPN
fnp-5809	393	14	,	,	PUNCT
fnp-5809	393	15	cosgrove	cosgrove	PROPN
fnp-5809	393	16	n	n	CCONJ
fnp-5809	393	17	,	,	PUNCT
fnp-5809	393	18	o'halloran	o'halloran	PROPN
fnp-5809	393	19	pj	pj	PROPN
fnp-5809	393	20	,	,	PUNCT
fnp-5809	393	21	ward	ward	NOUN
fnp-5809	393	22	e	e	NOUN
fnp-5809	393	23	,	,	PUNCT
fnp-5809	393	24	cocchiglia	cocchiglia	PROPN
fnp-5809	393	25	s	s	PART
fnp-5809	393	26	,	,	PUNCT
fnp-5809	393	27	hartmaier	hartmaier	NOUN
fnp-5809	393	28	r	r	NOUN
fnp-5809	393	29	,	,	PUNCT
fnp-5809	393	30	castro	castro	PROPN
fnp-5809	393	31	ca	can	AUX
fnp-5809	393	32	,	,	PUNCT
fnp-5809	393	33	zhu	zhu	PROPN
fnp-5809	393	34	l	l	PROPN
fnp-5809	393	35	,	,	PUNCT
fnp-5809	393	36	tseng	tseng	PROPN
fnp-5809	393	37	gc	gc	PROPN
fnp-5809	393	38	,	,	PUNCT
fnp-5809	393	39	lucas	lucas	PROPN
fnp-5809	393	40	pc	pc	PROPN
fnp-5809	393	41	,	,	PUNCT
fnp-5809	393	42	puhalla	puhalla	NOUN
fnp-5809	393	43	sl	sl	NOUN
fnp-5809	393	44	,	,	PUNCT
fnp-5809	393	45	brufsky	brufsky	NOUN
fnp-5809	393	46	am	be	AUX
fnp-5809	393	47	,	,	PUNCT
fnp-5809	393	48	hamilton	hamilton	PROPN
fnp-5809	393	49	rl	rl	PROPN
fnp-5809	393	50	,	,	PUNCT
fnp-5809	393	51	mathew	mathew	PROPN
fnp-5809	393	52	a	a	PROPN
fnp-5809	393	53	,	,	PUNCT
fnp-5809	393	54	leone	leone	NOUN
fnp-5809	393	55	jp	jp	NOUN
fnp-5809	393	56	,	,	PUNCT
fnp-5809	393	57	basudan	basudan	PROPN
fnp-5809	393	58	a	a	PRON
fnp-5809	393	59	,	,	PUNCT
fnp-5809	393	60	hudson	hudson	PROPN
fnp-5809	393	61	l	l	PROPN
fnp-5809	393	62	,	,	PUNCT
fnp-5809	393	63	dwyer	dwyer	PROPN
fnp-5809	393	64	r	r	PROPN
fnp-5809	393	65	,	,	PUNCT
fnp-5809	393	66	das	das	PROPN
fnp-5809	393	67	s	s	PROPN
fnp-5809	393	68	,	,	PUNCT
fnp-5809	393	69	o'connor	o'connor	PROPN
fnp-5809	393	70	dp	dp	PROPN
fnp-5809	393	71	,	,	PUNCT
fnp-5809	393	72	buckley	buckley	PROPN
fnp-5809	393	73	pg	pg	PROPN
fnp-5809	393	74	,	,	PUNCT
fnp-5809	393	75	farrell	farrell	PROPN
fnp-5809	393	76	m	m	PROPN
fnp-5809	393	77	,	,	PUNCT
fnp-5809	393	78	hill	hill	PROPN
fnp-5809	393	79	adk	adk	PROPN
fnp-5809	393	80	,	,	PUNCT
fnp-5809	393	81	oesterreich	oesterreich	PROPN
fnp-5809	393	82	s	s	PROPN
fnp-5809	393	83	,	,	PUNCT
fnp-5809	393	84	lee	lee	PROPN
fnp-5809	393	85	av	av	PROPN
fnp-5809	393	86	,	,	PUNCT
fnp-5809	393	87	young	young	ADJ
fnp-5809	393	88	ls	ls	PROPN
fnp-5809	393	89	.	.	PUNCT
fnp-5809	394	1	transcriptome	transcriptome	ADJ
fnp-5809	394	2	characterization	characterization	NOUN
fnp-5809	394	3	of	of	ADP
fnp-5809	394	4	matched	match	VERB
fnp-5809	394	5	primary	primary	ADJ
fnp-5809	394	6	breast	breast	NOUN
fnp-5809	394	7	and	and	CCONJ
fnp-5809	394	8	brain	brain	NOUN
fnp-5809	394	9	metastatic	metastatic	ADJ
fnp-5809	394	10	tumors	tumor	NOUN
fnp-5809	394	11	to	to	PART
fnp-5809	394	12	detect	detect	VERB
fnp-5809	394	13	novel	novel	ADJ
fnp-5809	394	14	actionable	actionable	ADJ
fnp-5809	394	15	targets	target	NOUN
fnp-5809	394	16	.	.	PUNCT
fnp-5809	395	1	j	j	PROPN
fnp-5809	395	2	natl	natl	PROPN
fnp-5809	395	3	cancer	cancer	PROPN
fnp-5809	395	4	inst	inst	PROPN
fnp-5809	395	5	.	.	PROPN
fnp-5809	395	6	2019	2019	NUM
fnp-5809	395	7	apr	apr	NOUN
fnp-5809	395	8	1;111(4):388	1;111(4):388	NUM
fnp-5809	395	9	-	-	SYM
fnp-5809	395	10	398	398	NUM
fnp-5809	395	11	.	.	PUNCT
fnp-5809	396	1	https://doi.org/10.1093/jnci/djy110	https://doi.org/10.1093/jnci/djy110	PROPN
fnp-5809	396	2	.	.	PUNCT
fnp-5809	397	1	pmid	pmid	NOUN
fnp-5809	397	2	:	:	PUNCT
fnp-5809	397	3	29961873	29961873	NUM
fnp-5809	397	4	.	.	PUNCT
fnp-5809	398	1	29	29	NUM
fnp-5809	398	2	.	.	PUNCT
fnp-5809	398	3	venkataramani	venkataramani	PROPN
fnp-5809	398	4	v	v	PROPN
fnp-5809	398	5	,	,	PUNCT
fnp-5809	398	6	tanev	tanev	NOUN
fnp-5809	398	7	di	di	NOUN
fnp-5809	398	8	,	,	PUNCT
fnp-5809	398	9	strahle	strahle	NOUN
fnp-5809	398	10	c	c	NOUN
fnp-5809	398	11	,	,	PUNCT
fnp-5809	398	12	studier	studi	ADJ
fnp-5809	398	13	-	-	PUNCT
fnp-5809	398	14	fischer	fischer	PROPN
fnp-5809	398	15	a	a	PRON
fnp-5809	398	16	,	,	PUNCT
fnp-5809	398	17	fankhauser	fankhauser	NOUN
fnp-5809	398	18	l	l	PROPN
fnp-5809	398	19	,	,	PUNCT
fnp-5809	398	20	kessler	kessler	PROPN
fnp-5809	398	21	t	t	PROPN
fnp-5809	398	22	,	,	PUNCT
fnp-5809	398	23	körber	körber	PROPN
fnp-5809	398	24	c	c	PROPN
fnp-5809	398	25	,	,	PUNCT
fnp-5809	398	26	kardorff	kardorff	PROPN
fnp-5809	398	27	m	m	PROPN
fnp-5809	398	28	,	,	PUNCT
fnp-5809	398	29	ratliff	ratliff	PROPN
fnp-5809	398	30	m	m	PROPN
fnp-5809	398	31	,	,	PUNCT
fnp-5809	398	32	xie	xie	PROPN
fnp-5809	398	33	r	r	PROPN
fnp-5809	398	34	,	,	PUNCT
fnp-5809	398	35	horstmann	horstmann	PROPN
fnp-5809	398	36	h	h	NOUN
fnp-5809	398	37	,	,	PUNCT
fnp-5809	398	38	messer	messer	PROPN
fnp-5809	398	39	m	m	PROPN
fnp-5809	398	40	,	,	PUNCT
fnp-5809	398	41	paik	paik	PROPN
fnp-5809	398	42	sp	sp	PROPN
fnp-5809	398	43	,	,	PUNCT
fnp-5809	398	44	knabbe	knabbe	NOUN
fnp-5809	398	45	j	j	PROPN
fnp-5809	398	46	,	,	PUNCT
fnp-5809	398	47	sahm	sahm	PROPN
fnp-5809	398	48	f	f	PROPN
fnp-5809	398	49	,	,	PUNCT
fnp-5809	398	50	kurz	kurz	PROPN
fnp-5809	398	51	ft	ft	PROPN
fnp-5809	398	52	,	,	PUNCT
fnp-5809	398	53	acikgöz	acikgöz	NOUN
fnp-5809	398	54	aa	aa	NOUN
fnp-5809	398	55	,	,	PUNCT
fnp-5809	398	56	herrmannsdörfer	herrmannsdörfer	NOUN
fnp-5809	398	57	f	f	PROPN
fnp-5809	398	58	,	,	PUNCT
fnp-5809	398	59	agarwal	agarwal	PROPN
fnp-5809	398	60	a	a	PRON
fnp-5809	398	61	,	,	PUNCT
fnp-5809	398	62	bergles	bergle	NOUN
fnp-5809	398	63	de	de	X
fnp-5809	398	64	,	,	PUNCT
fnp-5809	398	65	chalmers	chalmer	VERB
fnp-5809	398	66	a	a	DET
fnp-5809	398	67	,	,	PUNCT
fnp-5809	398	68	miletic	miletic	ADJ
fnp-5809	398	69	h	h	NOUN
fnp-5809	398	70	,	,	PUNCT
fnp-5809	398	71	turcan	turcan	PROPN
fnp-5809	398	72	s	s	PROPN
fnp-5809	398	73	,	,	PUNCT
fnp-5809	398	74	mawrin	mawrin	NOUN
fnp-5809	398	75	c	c	NOUN
fnp-5809	398	76	,	,	PUNCT
fnp-5809	398	77	hänggi	hänggi	NOUN
fnp-5809	398	78	d	d	PROPN
fnp-5809	398	79	,	,	PUNCT
fnp-5809	398	80	liu	liu	PROPN
fnp-5809	398	81	hk	hk	PROPN
fnp-5809	398	82	,	,	PUNCT
fnp-5809	398	83	wick	wick	PROPN
fnp-5809	398	84	w	w	PROPN
fnp-5809	398	85	,	,	PUNCT
fnp-5809	398	86	winkler	winkler	PROPN
fnp-5809	398	87	f	f	PROPN
fnp-5809	398	88	,	,	PUNCT
fnp-5809	398	89	kuner	kuner	ADJ
fnp-5809	398	90	t.	t.	ADJ
fnp-5809	398	91	glutamatergic	glutamatergic	ADJ
fnp-5809	398	92	synaptic	synaptic	ADJ
fnp-5809	398	93	input	input	NOUN
fnp-5809	398	94	to	to	ADP
fnp-5809	398	95	glioma	glioma	NOUN
fnp-5809	398	96	cells	cell	NOUN
fnp-5809	398	97	drives	drive	VERB
fnp-5809	398	98	brain	brain	VERB
fnp-5809	398	99	tumour	tumour	NOUN
fnp-5809	398	100	progression	progression	NOUN
fnp-5809	398	101	.	.	PUNCT
fnp-5809	399	1	nature	nature	NOUN
fnp-5809	399	2	.	.	PUNCT
fnp-5809	400	1	2019	2019	NUM
fnp-5809	400	2	sep;573(7775):532	sep;573(7775):532	NOUN
fnp-5809	400	3	-	-	PUNCT
fnp-5809	400	4	538	538	NUM
fnp-5809	400	5	.	.	PUNCT
fnp-5809	401	1	https://doi.org/10.1038/s41586-019-1564-x	https://doi.org/10.1038/s41586-019-1564-x	PROPN
fnp-5809	401	2	.	.	PUNCT
fnp-5809	402	1	pmid	pmid	NOUN
fnp-5809	402	2	:	:	PUNCT
fnp-5809	402	3	31534219	31534219	NUM
fnp-5809	402	4	.	.	PUNCT
fnp-5809	403	1	30	30	NUM
fnp-5809	403	2	.	.	PUNCT
fnp-5809	404	1	venkataramani	venkataramani	PROPN
fnp-5809	404	2	v	v	PROPN
fnp-5809	404	3	,	,	PUNCT
fnp-5809	404	4	yang	yang	PROPN
fnp-5809	404	5	y	y	PROPN
fnp-5809	404	6	,	,	PUNCT
fnp-5809	404	7	schubert	schubert	PROPN
fnp-5809	404	8	mc	mc	PROPN
fnp-5809	404	9	,	,	PUNCT
fnp-5809	404	10	reyhan	reyhan	PROPN
fnp-5809	404	11	e	e	PROPN
fnp-5809	404	12	,	,	PUNCT
fnp-5809	404	13	tetzlaff	tetzlaff	PROPN
fnp-5809	404	14	sk	sk	PROPN
fnp-5809	404	15	,	,	PUNCT
fnp-5809	404	16	wißmann	wißmann	NOUN
fnp-5809	404	17	n	n	PART
fnp-5809	404	18	,	,	PUNCT
fnp-5809	404	19	botz	botz	PROPN
fnp-5809	404	20	m	m	PROPN
fnp-5809	404	21	,	,	PUNCT
fnp-5809	404	22	soyka	soyka	PROPN
fnp-5809	404	23	sj	sj	PROPN
fnp-5809	404	24	,	,	PUNCT
fnp-5809	404	25	beretta	beretta	PROPN
fnp-5809	404	26	ca	can	AUX
fnp-5809	404	27	,	,	PUNCT
fnp-5809	404	28	pramatarov	pramatarov	PROPN
fnp-5809	404	29	rl	rl	PROPN
fnp-5809	404	30	,	,	PUNCT
fnp-5809	404	31	fankhauser	fankhauser	NOUN
fnp-5809	404	32	l	l	NOUN
fnp-5809	404	33	,	,	PUNCT
fnp-5809	404	34	garofano	garofano	ADJ
fnp-5809	404	35	l	l	NOUN
fnp-5809	404	36	,	,	PUNCT
fnp-5809	404	37	freudenberg	freudenberg	PROPN
fnp-5809	404	38	a	a	X
fnp-5809	404	39	,	,	PUNCT
fnp-5809	404	40	wagner	wagner	PROPN
fnp-5809	404	41	j	j	PROPN
fnp-5809	404	42	,	,	PUNCT
fnp-5809	404	43	tanev	tanev	PROPN
fnp-5809	404	44	di	di	PROPN
fnp-5809	404	45	,	,	PUNCT
fnp-5809	404	46	ratliff	ratliff	PROPN
fnp-5809	404	47	m	m	PROPN
fnp-5809	404	48	,	,	PUNCT
fnp-5809	404	49	xie	xie	PROPN
fnp-5809	404	50	r	r	PROPN
fnp-5809	404	51	,	,	PUNCT
fnp-5809	404	52	kessler	kessler	PROPN
fnp-5809	404	53	t	t	PROPN
fnp-5809	404	54	,	,	PUNCT
fnp-5809	404	55	hoffmann	hoffmann	PROPN
fnp-5809	404	56	dc	dc	PROPN
fnp-5809	404	57	,	,	PUNCT
fnp-5809	404	58	hai	hai	PROPN
fnp-5809	404	59	l	l	PROPN
fnp-5809	404	60	,	,	PUNCT
fnp-5809	404	61	dörflinger	dörflinger	PROPN
fnp-5809	404	62	y	y	PROPN
fnp-5809	404	63	,	,	PUNCT
fnp-5809	404	64	hoppe	hoppe	PROPN
fnp-5809	404	65	s	s	PROPN
fnp-5809	404	66	,	,	PUNCT
fnp-5809	404	67	yabo	yabo	PROPN
fnp-5809	404	68	ya	ya	PROPN
fnp-5809	404	69	,	,	PUNCT
fnp-5809	404	70	golebiewska	golebiewska	VERB
fnp-5809	404	71	a	a	DET
fnp-5809	404	72	,	,	PUNCT
fnp-5809	404	73	niclou	niclou	ADJ
fnp-5809	404	74	sp	sp	PROPN
fnp-5809	404	75	,	,	PUNCT
fnp-5809	404	76	sahm	sahm	PROPN
fnp-5809	404	77	f	f	PROPN
fnp-5809	404	78	,	,	PUNCT
fnp-5809	404	79	lasorella	lasorella	PROPN
fnp-5809	404	80	a	a	PROPN
fnp-5809	404	81	,	,	PUNCT
fnp-5809	404	82	slowik	slowik	PROPN
fnp-5809	404	83	m	m	PROPN
fnp-5809	404	84	,	,	PUNCT
fnp-5809	404	85	döring	döre	VERB
fnp-5809	404	86	l	l	NOUN
fnp-5809	404	87	,	,	PUNCT
fnp-5809	404	88	iavarone	iavarone	NOUN
fnp-5809	404	89	a	a	NOUN
fnp-5809	404	90	,	,	PUNCT
fnp-5809	404	91	wick	wick	PROPN
fnp-5809	404	92	w	w	PROPN
fnp-5809	404	93	,	,	PUNCT
fnp-5809	404	94	kuner	kuner	PROPN
fnp-5809	404	95	t	t	PROPN
fnp-5809	404	96	,	,	PUNCT
fnp-5809	404	97	winkler	winkler	PROPN
fnp-5809	404	98	f.	f.	PROPN
fnp-5809	404	99	glioblastoma	glioblastoma	PROPN
fnp-5809	404	100	hijacks	hijack	VERB
fnp-5809	404	101	neuronal	neuronal	ADJ
fnp-5809	404	102	mechanisms	mechanism	NOUN
fnp-5809	404	103	for	for	ADP
fnp-5809	404	104	brain	brain	NOUN
fnp-5809	404	105	invasion	invasion	NOUN
fnp-5809	404	106	.	.	PUNCT
fnp-5809	405	1	cell	cell	NOUN
fnp-5809	405	2	.	.	PUNCT
fnp-5809	406	1	2022	2022	NUM
fnp-5809	406	2	aug	aug	PROPN
fnp-5809	406	3	4;185(16):2899	4;185(16):2899	PROPN
fnp-5809	406	4	-	-	PUNCT
fnp-5809	406	5	2917.e31	2917.e31	PROPN
fnp-5809	406	6	.	.	PUNCT
fnp-5809	407	1	https://doi.org/10.1016/j.cell.2022.06.054	https://doi.org/10.1016/j.cell.2022.06.054	PROPN
fnp-5809	407	2	.	.	PUNCT
fnp-5809	408	1	pmid	pmid	NOUN
fnp-5809	408	2	:	:	PUNCT
fnp-5809	408	3	35914528	35914528	NUM
fnp-5809	408	4	.	.	PUNCT
fnp-5809	409	1	31	31	NUM
fnp-5809	409	2	.	.	PUNCT
fnp-5809	410	1	vermeulen	vermeulen	PROPN
fnp-5809	410	2	c	c	PROPN
fnp-5809	410	3	,	,	PUNCT
fnp-5809	410	4	pagès	pagès	NOUN
fnp-5809	410	5	-	-	PUNCT
fnp-5809	410	6	gallego	gallego	NOUN
fnp-5809	410	7	m	m	PROPN
fnp-5809	410	8	,	,	PUNCT
fnp-5809	410	9	kester	kester	PROPN
fnp-5809	410	10	l	l	PROPN
fnp-5809	410	11	,	,	PUNCT
fnp-5809	410	12	kranendonk	kranendonk	PROPN
fnp-5809	410	13	meg	meg	PROPN
fnp-5809	410	14	,	,	PUNCT
fnp-5809	410	15	wesseling	wessele	VERB
fnp-5809	410	16	p	p	PRON
fnp-5809	410	17	,	,	PUNCT
fnp-5809	410	18	verburg	verburg	NOUN
fnp-5809	410	19	n	n	CCONJ
fnp-5809	410	20	,	,	PUNCT
fnp-5809	410	21	de	de	X
fnp-5809	410	22	witt	witt	PROPN
fnp-5809	410	23	hamer	hamer	PROPN
fnp-5809	410	24	p	p	PROPN
fnp-5809	410	25	,	,	PUNCT
fnp-5809	410	26	kooi	kooi	PROPN
fnp-5809	410	27	ej	ej	PROPN
fnp-5809	410	28	,	,	PUNCT
fnp-5809	410	29	dankmeijer	dankmeijer	NOUN
fnp-5809	410	30	l	l	PROPN
fnp-5809	410	31	,	,	PUNCT
fnp-5809	410	32	van	van	PROPN
fnp-5809	410	33	der	der	PROPN
fnp-5809	410	34	lugt	lugt	PROPN
fnp-5809	410	35	j	j	PROPN
fnp-5809	410	36	,	,	PUNCT
fnp-5809	410	37	van	van	PROPN
fnp-5809	410	38	baarsen	baarsen	PROPN
fnp-5809	410	39	k	k	PROPN
fnp-5809	410	40	,	,	PUNCT
fnp-5809	410	41	hoving	hoving	PROPN
fnp-5809	410	42	ew	ew	NOUN
fnp-5809	410	43	,	,	PUNCT
fnp-5809	410	44	tops	top	VERB
fnp-5809	410	45	bbj	bbj	PROPN
fnp-5809	410	46	,	,	PUNCT
fnp-5809	410	47	de	de	PROPN
fnp-5809	410	48	ridder	ridder	PROPN
fnp-5809	410	49	j.	j.	PROPN
fnp-5809	410	50	ultra	ultra	ADJ
fnp-5809	410	51	-	-	ADJ
fnp-5809	410	52	fast	fast	ADJ
fnp-5809	410	53	deep	deep	ADV
fnp-5809	410	54	-	-	PUNCT
fnp-5809	410	55	learned	learn	VERB
fnp-5809	410	56	cns	cns	NOUN
fnp-5809	410	57	tumour	tumour	NOUN
fnp-5809	410	58	classification	classification	NOUN
fnp-5809	410	59	during	during	ADP
fnp-5809	410	60	surgery	surgery	NOUN
fnp-5809	410	61	.	.	PUNCT
fnp-5809	411	1	nature	nature	NOUN
fnp-5809	411	2	.	.	PUNCT
fnp-5809	412	1	2023	2023	NUM
fnp-5809	412	2	oct;622(7984):842	oct;622(7984):842	NOUN
fnp-5809	412	3	-	-	PUNCT
fnp-5809	412	4	849	849	NUM
fnp-5809	412	5	.	.	PUNCT
fnp-5809	413	1	https://doi.org/10.1038/s41586-023-06615-2	https://doi.org/10.1038/s41586-023-06615-2	NUM
fnp-5809	413	2	.	.	PUNCT
fnp-5809	414	1	pmid	pmid	NOUN
fnp-5809	414	2	:	:	PUNCT
fnp-5809	414	3	37821699	37821699	NUM
fnp-5809	414	4	.	.	PUNCT
fnp-5809	415	1	32	32	NUM
fnp-5809	415	2	.	.	PUNCT
fnp-5809	416	1	watson	watson	PROPN
fnp-5809	416	2	dc	dc	PROPN
fnp-5809	416	3	,	,	PUNCT
fnp-5809	416	4	bayik	bayik	NOUN
fnp-5809	416	5	d	d	PROPN
fnp-5809	416	6	,	,	PUNCT
fnp-5809	416	7	storevik	storevik	PROPN
fnp-5809	416	8	s	s	PART
fnp-5809	416	9	,	,	PUNCT
fnp-5809	416	10	moreino	moreino	NOUN
fnp-5809	416	11	ss	ss	PROPN
fnp-5809	416	12	,	,	PUNCT
fnp-5809	416	13	sprowls	sprowls	PROPN
fnp-5809	416	14	sa	sa	PROPN
fnp-5809	416	15	,	,	PUNCT
fnp-5809	416	16	han	han	PROPN
fnp-5809	416	17	j	j	PROPN
fnp-5809	416	18	,	,	PUNCT
fnp-5809	416	19	augustsson	augustsson	PROPN
fnp-5809	416	20	mt	mt	PROPN
fnp-5809	416	21	,	,	PUNCT
fnp-5809	416	22	lauko	lauko	PROPN
fnp-5809	416	23	a	a	X
fnp-5809	416	24	,	,	PUNCT
fnp-5809	416	25	sravya	sravya	NOUN
fnp-5809	416	26	p	p	NOUN
fnp-5809	416	27	,	,	PUNCT
fnp-5809	416	28	røsland	røsland	NOUN
fnp-5809	416	29	gv	gv	ADP
fnp-5809	416	30	,	,	PUNCT
fnp-5809	416	31	troike	troike	PROPN
fnp-5809	416	32	k	k	PROPN
fnp-5809	416	33	,	,	PUNCT
fnp-5809	416	34	tronstad	tronstad	PROPN
fnp-5809	416	35	kj	kj	PROPN
fnp-5809	416	36	,	,	PUNCT
fnp-5809	416	37	wang	wang	PROPN
fnp-5809	416	38	s	s	PROPN
fnp-5809	416	39	,	,	PUNCT
fnp-5809	416	40	sarnow	sarnow	PROPN
fnp-5809	416	41	k	k	PROPN
fnp-5809	416	42	,	,	PUNCT
fnp-5809	416	43	kay	kay	PROPN
fnp-5809	417	1	k	k	NOUN
fnp-5809	417	2	,	,	PUNCT
fnp-5809	417	3	lunavat	lunavat	NOUN
fnp-5809	417	4	tr	tr	VERB
fnp-5809	417	5	,	,	PUNCT
fnp-5809	417	6	silver	silver	NOUN
fnp-5809	417	7	dj	dj	NOUN
fnp-5809	417	8	,	,	PUNCT
fnp-5809	417	9	dayal	dayal	PROPN
fnp-5809	417	10	s	s	PROPN
fnp-5809	417	11	,	,	PUNCT
fnp-5809	417	12	joseph	joseph	PROPN
fnp-5809	417	13	jv	jv	PROPN
fnp-5809	417	14	,	,	PUNCT
fnp-5809	417	15	mulkearns	mulkearn	NOUN
fnp-5809	417	16	-	-	PUNCT
fnp-5809	417	17	hubert	hubert	PROPN
fnp-5809	417	18	e	e	PROPN
fnp-5809	417	19	,	,	PUNCT
fnp-5809	417	20	ystaas	ystaas	NOUN
fnp-5809	417	21	lar	lar	ADJ
fnp-5809	417	22	,	,	PUNCT
fnp-5809	417	23	deshpande	deshpande	VERB
fnp-5809	417	24	g	g	PROPN
fnp-5809	417	25	,	,	PUNCT
fnp-5809	417	26	guyon	guyon	PROPN
fnp-5809	417	27	j	j	PROPN
fnp-5809	417	28	,	,	PUNCT
fnp-5809	417	29	zhou	zhou	PROPN
fnp-5809	417	30	y	y	PROPN
fnp-5809	417	31	,	,	PUNCT
fnp-5809	417	32	magaut	magaut	PROPN
fnp-5809	417	33	cr	cr	PROPN
fnp-5809	417	34	,	,	PUNCT
fnp-5809	417	35	seder	seder	PROPN
fnp-5809	417	36	j	j	PROPN
fnp-5809	417	37	,	,	PUNCT
fnp-5809	417	38	neises	neise	VERB
fnp-5809	417	39	l	l	NOUN
fnp-5809	417	40	,	,	PUNCT
fnp-5809	417	41	williford	williford	PROPN
fnp-5809	417	42	se	se	PROPN
fnp-5809	417	43	,	,	PUNCT
fnp-5809	417	44	meiser	meiser	PROPN
fnp-5809	417	45	j	j	PROPN
fnp-5809	417	46	,	,	PUNCT
fnp-5809	417	47	scott	scott	PROPN
fnp-5809	417	48	aj	aj	PROPN
fnp-5809	417	49	,	,	PUNCT
fnp-5809	417	50	sajjakulnukit	sajjakulnukit	ADJ
fnp-5809	417	51	p	p	NOUN
fnp-5809	417	52	,	,	PUNCT
fnp-5809	417	53	mears	mears	PROPN
fnp-5809	417	54	ja	ja	PROPN
fnp-5809	417	55	,	,	PUNCT
fnp-5809	417	56	bjerkvig	bjerkvig	PROPN
fnp-5809	417	57	r	r	PROPN
fnp-5809	417	58	,	,	PUNCT
fnp-5809	417	59	chakraborty	chakraborty	PROPN
fnp-5809	417	60	a	a	X
fnp-5809	417	61	,	,	PUNCT
fnp-5809	417	62	daubon	daubon	PROPN
fnp-5809	417	63	t	t	PROPN
fnp-5809	417	64	,	,	PUNCT
fnp-5809	417	65	cheng	cheng	PROPN
fnp-5809	417	66	f	f	PROPN
fnp-5809	417	67	,	,	PUNCT
fnp-5809	418	1	lyssiotis	lyssiotis	PRON
fnp-5809	418	2	ca	ca	NOUN
fnp-5809	418	3	,	,	PUNCT
fnp-5809	418	4	wahl	wahl	PROPN
fnp-5809	418	5	dr	dr	PROPN
fnp-5809	418	6	,	,	PUNCT
fnp-5809	418	7	hjelmeland	hjelmeland	PROPN
fnp-5809	418	8	ab	ab	PROPN
fnp-5809	418	9	,	,	PUNCT
fnp-5809	418	10	hossain	hossain	PROPN
fnp-5809	418	11	ja	ja	PROPN
fnp-5809	418	12	,	,	PUNCT
fnp-5809	418	13	miletic	miletic	ADJ
fnp-5809	418	14	h	h	NOUN
fnp-5809	418	15	,	,	PUNCT
fnp-5809	418	16	lathia	lathia	PROPN
fnp-5809	418	17	jd	jd	PROPN
fnp-5809	418	18	.	.	PUNCT
fnp-5809	418	19	gap43	gap43	PROPN
fnp-5809	418	20	-	-	PUNCT
fnp-5809	418	21	dependent	dependent	ADJ
fnp-5809	418	22	mitochondria	mitochondria	NOUN
fnp-5809	418	23	transfer	transfer	NOUN
fnp-5809	418	24	from	from	ADP
fnp-5809	418	25	astrocytes	astrocyte	NOUN
fnp-5809	418	26	enhances	enhance	VERB
fnp-5809	418	27	glioblastoma	glioblastoma	NOUN
fnp-5809	418	28	tumorigenicity	tumorigenicity	NOUN
fnp-5809	418	29	.	.	PUNCT
fnp-5809	419	1	nat	nat	NOUN
fnp-5809	419	2	cancer	cancer	NOUN
fnp-5809	419	3	.	.	PUNCT
fnp-5809	420	1	2023	2023	NUM
fnp-5809	420	2	may;4(5):648	may;4(5):648	PROPN
fnp-5809	420	3	-	-	PUNCT
fnp-5809	420	4	664	664	NUM
fnp-5809	420	5	.	.	PUNCT
fnp-5809	420	6	https://doi.org/10.1038/s43018-023-00556-5	https://doi.org/10.1038/s43018-023-00556-5	PROPN
fnp-5809	420	7	.	.	PUNCT
fnp-5809	421	1	pmid	pmid	NOUN
fnp-5809	421	2	:	:	PUNCT
fnp-5809	421	3	37169842	37169842	NUM
fnp-5809	421	4	.	.	PUNCT
fnp-5809	422	1	33	33	NUM
fnp-5809	422	2	.	.	PUNCT
fnp-5809	423	1	world	world	PROPN
fnp-5809	423	2	health	health	PROPN
fnp-5809	423	3	organization	organization	PROPN
fnp-5809	423	4	classification	classification	NOUN
fnp-5809	423	5	of	of	ADP
fnp-5809	423	6	tumours	tumour	NOUN
fnp-5809	423	7	of	of	ADP
fnp-5809	423	8	the	the	DET
fnp-5809	423	9	central	central	ADJ
fnp-5809	423	10	nervous	nervous	ADJ
fnp-5809	423	11	system	system	NOUN
fnp-5809	423	12	.	.	PUNCT
fnp-5809	424	1	5th	5th	ADJ
fnp-5809	424	2	ed	ed	NOUN
fnp-5809	424	3	.	.	PUNCT
fnp-5809	425	1	lyon	lyon	PROPN
fnp-5809	425	2	:	:	PUNCT
fnp-5809	425	3	international	international	ADJ
fnp-5809	425	4	agency	agency	NOUN
fnp-5809	425	5	for	for	ADP
fnp-5809	425	6	research	research	NOUN
fnp-5809	425	7	on	on	ADP
fnp-5809	425	8	cancer	cancer	NOUN
fnp-5809	425	9	;	;	PUNCT
fnp-5809	425	10	2021	2021	NUM
fnp-5809	425	11	.	.	PUNCT
fnp-5809	426	1	34	34	NUM
fnp-5809	426	2	.	.	PUNCT
fnp-5809	426	3	yan	yan	PROPN
fnp-5809	427	1	h	h	PROPN
fnp-5809	427	2	,	,	PUNCT
fnp-5809	427	3	parsons	parsons	PROPN
fnp-5809	427	4	dw	dw	PROPN
fnp-5809	427	5	,	,	PUNCT
fnp-5809	427	6	jin	jin	PROPN
fnp-5809	427	7	g	g	PROPN
fnp-5809	427	8	,	,	PUNCT
fnp-5809	427	9	mclendon	mclendon	PROPN
fnp-5809	427	10	r	r	PROPN
fnp-5809	427	11	,	,	PUNCT
fnp-5809	427	12	rasheed	rasheed	PROPN
fnp-5809	427	13	ba	ba	PROPN
fnp-5809	427	14	,	,	PUNCT
fnp-5809	427	15	yuan	yuan	PROPN
fnp-5809	427	16	w	w	PROPN
fnp-5809	427	17	,	,	PUNCT
fnp-5809	427	18	kos	kos	PROPN
fnp-5809	427	19	i	i	PRON
fnp-5809	427	20	,	,	PUNCT
fnp-5809	427	21	batinic	batinic	NOUN
fnp-5809	427	22	-	-	PUNCT
fnp-5809	427	23	haberle	haberle	NOUN
fnp-5809	427	24	i	i	PROPN
fnp-5809	427	25	,	,	PUNCT
fnp-5809	427	26	jones	jones	PROPN
fnp-5809	427	27	s	s	PROPN
fnp-5809	427	28	,	,	PUNCT
fnp-5809	427	29	riggins	riggins	PROPN
fnp-5809	427	30	gj	gj	PROPN
fnp-5809	427	31	,	,	PUNCT
fnp-5809	427	32	friedman	friedman	PROPN
fnp-5809	427	33	h	h	PROPN
fnp-5809	427	34	,	,	PUNCT
fnp-5809	427	35	friedman	friedman	PROPN
fnp-5809	427	36	a	a	X
fnp-5809	427	37	,	,	PUNCT
fnp-5809	427	38	reardon	reardon	PROPN
fnp-5809	427	39	d	d	PROPN
fnp-5809	427	40	,	,	PUNCT
fnp-5809	427	41	herndon	herndon	PROPN
fnp-5809	427	42	j	j	PROPN
fnp-5809	427	43	,	,	PUNCT
fnp-5809	427	44	kinzler	kinzler	NOUN
fnp-5809	427	45	kw	kw	PROPN
fnp-5809	427	46	,	,	PUNCT
fnp-5809	427	47	velculescu	velculescu	NOUN
fnp-5809	427	48	ve	ve	PROPN
fnp-5809	427	49	,	,	PUNCT
fnp-5809	427	50	vogelstein	vogelstein	PROPN
fnp-5809	427	51	b	b	NOUN
fnp-5809	427	52	,	,	PUNCT
fnp-5809	427	53	bigner	bigner	NOUN
fnp-5809	427	54	dd	dd	NOUN
fnp-5809	427	55	.	.	PROPN
fnp-5809	427	56	idh1	idh1	PROPN
fnp-5809	427	57	and	and	CCONJ
fnp-5809	427	58	idh2	idh2	PROPN
fnp-5809	427	59	mutations	mutation	NOUN
fnp-5809	427	60	in	in	ADP
fnp-5809	427	61	gliomas	glioma	NOUN
fnp-5809	427	62	.	.	PUNCT
fnp-5809	428	1	n	n	X
fnp-5809	428	2	engl	engl	PROPN
fnp-5809	428	3	j	j	PROPN
fnp-5809	428	4	med	med	PROPN
fnp-5809	428	5	.	.	PUNCT
fnp-5809	429	1	2009	2009	NUM
fnp-5809	429	2	feb	feb	PROPN
fnp-5809	429	3	19;360(8):765	19;360(8):765	PROPN
fnp-5809	429	4	-	-	PUNCT
fnp-5809	429	5	73	73	NUM
fnp-5809	429	6	.	.	PUNCT
fnp-5809	430	1	https://doi.org/10.1056/nejmoa0808710	https://doi.org/10.1056/nejmoa0808710	ADJ
fnp-5809	430	2	.	.	PUNCT
fnp-5809	431	1	pmid	pmid	NOUN
fnp-5809	431	2	:	:	PUNCT
fnp-5809	431	3	19228619	19228619	NUM
fnp-5809	431	4	.	.	PUNCT
fnp-5809	432	1	35	35	NUM
fnp-5809	432	2	.	.	PUNCT
fnp-5809	432	3	zeiner	zeiner	PROPN
fnp-5809	432	4	ps	ps	PROPN
fnp-5809	432	5	,	,	PUNCT
fnp-5809	432	6	preusse	preusse	NOUN
fnp-5809	432	7	c	c	NOUN
fnp-5809	432	8	,	,	PUNCT
fnp-5809	432	9	golebiewska	golebiewska	VERB
fnp-5809	432	10	a	a	PRON
fnp-5809	432	11	,	,	PUNCT
fnp-5809	432	12	zinke	zinke	PROPN
fnp-5809	432	13	j	j	PROPN
fnp-5809	432	14	,	,	PUNCT
fnp-5809	432	15	iriondo	iriondo	NOUN
fnp-5809	432	16	a	a	X
fnp-5809	432	17	,	,	PUNCT
fnp-5809	432	18	muller	muller	NOUN
fnp-5809	432	19	a	a	NOUN
fnp-5809	432	20	,	,	PUNCT
fnp-5809	432	21	kaoma	kaoma	PROPN
fnp-5809	432	22	t	t	PROPN
fnp-5809	432	23	,	,	PUNCT
fnp-5809	432	24	filipski	filipski	PROPN
fnp-5809	432	25	k	k	PROPN
fnp-5809	432	26	,	,	PUNCT
fnp-5809	432	27	müller	müller	NOUN
fnp-5809	432	28	-	-	PUNCT
fnp-5809	432	29	eschner	eschner	NOUN
fnp-5809	432	30	m	m	PROPN
fnp-5809	432	31	,	,	PUNCT
fnp-5809	432	32	bernatz	bernatz	NOUN
fnp-5809	432	33	s	s	PROPN
fnp-5809	432	34	,	,	PUNCT
fnp-5809	432	35	blank	blank	ADJ
fnp-5809	432	36	ae	ae	PROPN
fnp-5809	432	37	,	,	PUNCT
fnp-5809	432	38	baumgarten	baumgarten	VERB
fnp-5809	432	39	p	p	PROPN
fnp-5809	432	40	,	,	PUNCT
fnp-5809	432	41	ilina	ilina	PROPN
fnp-5809	432	42	e	e	PROPN
fnp-5809	432	43	,	,	PUNCT
fnp-5809	432	44	grote	grote	VERB
fnp-5809	432	45	a	a	PRON
fnp-5809	432	46	,	,	PUNCT
fnp-5809	432	47	hansmann	hansmann	NOUN
fnp-5809	432	48	ml	ml	PROPN
fnp-5809	432	49	,	,	PUNCT
fnp-5809	432	50	verhoff	verhoff	PROPN
fnp-5809	432	51	ma	ma	PROPN
fnp-5809	432	52	,	,	PUNCT
fnp-5809	432	53	franz	franz	PROPN
fnp-5809	432	54	k	k	PROPN
fnp-5809	432	55	,	,	PUNCT
fnp-5809	432	56	feuerhake	feuerhake	NOUN
fnp-5809	432	57	f	f	NOUN
fnp-5809	432	58	,	,	PUNCT
fnp-5809	432	59	steinbach	steinbach	PROPN
fnp-5809	432	60	jp	jp	PROPN
fnp-5809	432	61	,	,	PUNCT
fnp-5809	432	62	wischhusen	wischhusen	PROPN
fnp-5809	432	63	j	j	PROPN
fnp-5809	432	64	,	,	PUNCT
fnp-5809	432	65	stenzel	stenzel	PROPN
fnp-5809	432	66	w	w	PROPN
fnp-5809	432	67	,	,	PUNCT
fnp-5809	432	68	niclou	niclou	ADJ
fnp-5809	432	69	sp	sp	NOUN
fnp-5809	432	70	,	,	PUNCT
fnp-5809	432	71	harter	harter	PROPN
fnp-5809	432	72	pn	pn	PROPN
fnp-5809	432	73	,	,	PUNCT
fnp-5809	432	74	mittelbronn	mittelbronn	PROPN
fnp-5809	432	75	m.	m.	NOUN
fnp-5809	432	76	distribution	distribution	NOUN
fnp-5809	432	77	and	and	CCONJ
fnp-5809	432	78	prognostic	prognostic	ADJ
fnp-5809	432	79	impact	impact	NOUN
fnp-5809	432	80	of	of	ADP
fnp-5809	432	81	microglia	microglia	ADJ
fnp-5809	432	82	/	/	SYM
fnp-5809	432	83	macrophage	macrophage	ADJ
fnp-5809	432	84	subpopulations	subpopulation	NOUN
fnp-5809	432	85	in	in	ADP
fnp-5809	432	86	gliomas	glioma	NOUN
fnp-5809	432	87	.	.	PUNCT
fnp-5809	433	1	brain	brain	NOUN
fnp-5809	433	2	pathol	pathol	NOUN
fnp-5809	433	3	.	.	PUNCT
fnp-5809	434	1	2019	2019	NUM
fnp-5809	434	2	jul;29(4):513	jul;29(4):513	SYM
fnp-5809	434	3	-	-	PUNCT
fnp-5809	434	4	529	529	NUM
fnp-5809	434	5	.	.	PUNCT
fnp-5809	435	1	https://doi.org/10.1111/bpa.12690	https://doi.org/10.1111/bpa.12690	NOUN
fnp-5809	435	2	.	.	PUNCT
fnp-5809	436	1	pmid	pmid	NOUN
fnp-5809	436	2	:	:	PUNCT
fnp-5809	436	3	30506802	30506802	NUM
fnp-5809	436	4	.	.	PUNCT
fnp-5809	437	1	copyright	copyright	NOUN
fnp-5809	437	2	:	:	PUNCT
fnp-5809	437	3	©	©	PROPN
fnp-5809	437	4	2024	2024	NUM
fnp-5809	437	5	the	the	DET
fnp-5809	437	6	author(s	author(s	NOUN
fnp-5809	437	7	)	)	PUNCT
fnp-5809	437	8	.	.	PUNCT
fnp-5809	438	1	this	this	PRON
fnp-5809	438	2	is	be	AUX
fnp-5809	438	3	an	an	DET
fnp-5809	438	4	open	open	ADJ
fnp-5809	438	5	access	access	NOUN
fnp-5809	438	6	article	article	NOUN
fnp-5809	438	7	distributed	distribute	VERB
fnp-5809	438	8	under	under	ADP
fnp-5809	438	9	the	the	DET
fnp-5809	438	10	terms	term	NOUN
fnp-5809	438	11	of	of	ADP
fnp-5809	438	12	the	the	DET
fnp-5809	438	13	creative	creative	ADJ
fnp-5809	438	14	commons	common	NOUN
fnp-5809	438	15	attribution	attribution	NOUN
fnp-5809	438	16	4.0	4.0	NUM
fnp-5809	438	17	international	international	ADJ
fnp-5809	438	18	license	license	NOUN
fnp-5809	438	19	(	(	PUNCT
fnp-5809	438	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5809	438	21	)	)	PUNCT
fnp-5809	438	22	,	,	PUNCT
fnp-5809	438	23	which	which	PRON
fnp-5809	438	24	permits	permit	VERB
fnp-5809	438	25	unrestricted	unrestricted	ADJ
fnp-5809	438	26	use	use	NOUN
fnp-5809	438	27	,	,	PUNCT
fnp-5809	438	28	distribution	distribution	NOUN
fnp-5809	438	29	,	,	PUNCT
fnp-5809	438	30	and	and	CCONJ
fnp-5809	438	31	reproduction	reproduction	NOUN
fnp-5809	438	32	in	in	ADP
fnp-5809	438	33	any	any	DET
fnp-5809	438	34	medium	medium	NOUN
fnp-5809	438	35	,	,	PUNCT
fnp-5809	438	36	provided	provide	VERB
fnp-5809	438	37	the	the	DET
fnp-5809	438	38	original	original	ADJ
fnp-5809	438	39	author	author	NOUN
fnp-5809	438	40	and	and	CCONJ
fnp-5809	438	41	source	source	NOUN
fnp-5809	438	42	are	be	AUX
fnp-5809	438	43	credited	credit	VERB
fnp-5809	438	44	,	,	PUNCT
fnp-5809	438	45	a	a	DET
fnp-5809	438	46	link	link	NOUN
fnp-5809	438	47	to	to	ADP
fnp-5809	438	48	the	the	DET
fnp-5809	438	49	creative	creative	ADJ
fnp-5809	438	50	commons	common	NOUN
fnp-5809	438	51	license	license	NOUN
fnp-5809	438	52	is	be	AUX
fnp-5809	438	53	provided	provide	VERB
fnp-5809	438	54	,	,	PUNCT
fnp-5809	438	55	and	and	CCONJ
fnp-5809	438	56	any	any	DET
fnp-5809	438	57	changes	change	NOUN
fnp-5809	438	58	are	be	AUX
fnp-5809	438	59	indicated	indicate	VERB
fnp-5809	438	60	.	.	PUNCT
fnp-5809	439	1	the	the	DET
fnp-5809	439	2	creative	creative	ADJ
fnp-5809	439	3	commons	common	NOUN
fnp-5809	439	4	public	public	ADJ
fnp-5809	439	5	domain	domain	NOUN
fnp-5809	439	6	dedication	dedication	NOUN
fnp-5809	439	7	waiver	waiver	NOUN
fnp-5809	439	8	(	(	PUNCT
fnp-5809	439	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-5809	439	10	)	)	PUNCT
fnp-5809	439	11	applies	apply	VERB
fnp-5809	439	12	to	to	ADP
fnp-5809	439	13	the	the	DET
fnp-5809	439	14	data	datum	NOUN
fnp-5809	439	15	made	make	VERB
fnp-5809	439	16	available	available	ADJ
fnp-5809	439	17	in	in	ADP
fnp-5809	439	18	this	this	DET
fnp-5809	439	19	article	article	NOUN
fnp-5809	439	20	,	,	PUNCT
fnp-5809	439	21	unless	unless	SCONJ
fnp-5809	439	22	otherwise	otherwise	ADV
fnp-5809	439	23	stated	state	VERB
fnp-5809	439	24	.	.	PUNCT