id	sid	tid	token	lemma	pos
fnp-5842	1	1	68th	68th	ADJ
fnp-5842	1	2	annual	annual	ADJ
fnp-5842	1	3	meeting	meeting	NOUN
fnp-5842	1	4	of	of	ADP
fnp-5842	1	5	the	the	DET
fnp-5842	1	6	german	german	ADJ
fnp-5842	1	7	society	society	NOUN
fnp-5842	1	8	of	of	ADP
fnp-5842	1	9	neuropathology	neuropathology	NOUN
fnp-5842	1	10	and	and	CCONJ
fnp-5842	1	11	neuroanatomy	neuroanatomy	NOUN
fnp-5842	1	12	(	(	PUNCT
fnp-5842	1	13	dgnn	dgnn	NOUN
fnp-5842	1	14	)	)	PUNCT
fnp-5842	1	15	meeting	meeting	NOUN
fnp-5842	1	16	abstracts	abstract	NOUN
fnp-5842	1	17	free	free	ADJ
fnp-5842	1	18	neuropathology	neuropathology	NOUN
fnp-5842	1	19	5:19	5:19	NUM
fnp-5842	1	20	(	(	PUNCT
fnp-5842	1	21	2024	2024	NUM
fnp-5842	1	22	)	)	PUNCT
fnp-5842	1	23	meeting	meeting	NOUN
fnp-5842	1	24	abstracts	abstract	VERB
fnp-5842	1	25	68th	68th	ADJ
fnp-5842	1	26	annual	annual	ADJ
fnp-5842	1	27	meeting	meeting	NOUN
fnp-5842	1	28	of	of	ADP
fnp-5842	1	29	the	the	DET
fnp-5842	1	30	german	german	ADJ
fnp-5842	1	31	society	society	NOUN
fnp-5842	1	32	of	of	ADP
fnp-5842	1	33	neuropathology	neuropathology	NOUN
fnp-5842	1	34	and	and	CCONJ
fnp-5842	1	35	neuroanatomy	neuroanatomy	NOUN
fnp-5842	1	36	(	(	PUNCT
fnp-5842	1	37	dgnn	dgnn	NOUN
fnp-5842	1	38	)	)	PUNCT
fnp-5842	1	39	meeting	meeting	NOUN
fnp-5842	1	40	abstracts	abstract	NOUN
fnp-5842	1	41	september	september	PROPN
fnp-5842	1	42	12–14	12–14	NUM
fnp-5842	1	43	,	,	PUNCT
fnp-5842	1	44	2024	2024	NUM
fnp-5842	1	45	,	,	PUNCT
fnp-5842	1	46	regensburg	regensburg	PROPN
fnp-5842	1	47	,	,	PUNCT
fnp-5842	1	48	germany	germany	PROPN
fnp-5842	1	49	german	german	ADJ
fnp-5842	1	50	society	society	NOUN
fnp-5842	1	51	of	of	ADP
fnp-5842	1	52	neuropathology	neuropathology	NOUN
fnp-5842	1	53	and	and	CCONJ
fnp-5842	1	54	neuroanatomy	neuroanatomy	NOUN
fnp-5842	1	55	(	(	PUNCT
fnp-5842	1	56	dgnn	dgnn	NOUN
fnp-5842	1	57	)	)	PUNCT
fnp-5842	1	58	submitted	submit	VERB
fnp-5842	1	59	:	:	PUNCT
fnp-5842	1	60	29	29	NUM
fnp-5842	1	61	august	august	PROPN
fnp-5842	1	62	2024	2024	NUM
fnp-5842	1	63	accepted	accept	VERB
fnp-5842	1	64	:	:	PUNCT
fnp-5842	1	65	02	02	NUM
fnp-5842	1	66	september	september	PROPN
fnp-5842	1	67	2024	2024	NUM
fnp-5842	1	68	published	publish	VERB
fnp-5842	1	69	:	:	PUNCT
fnp-5842	1	70	03	03	NUM
fnp-5842	1	71	september	september	PROPN
fnp-5842	1	72	2024	2024	NUM
fnp-5842	1	73	https://doi.org/10.17879/freeneuropathology-2024-5842	https://doi.org/10.17879/freeneuropathology-2024-5842	NOUN
fnp-5842	1	74	keywords	keyword	NOUN
fnp-5842	1	75	:	:	PUNCT
fnp-5842	1	76	german	german	ADJ
fnp-5842	1	77	society	society	NOUN
fnp-5842	1	78	of	of	ADP
fnp-5842	1	79	neuropathology	neuropathology	NOUN
fnp-5842	1	80	and	and	CCONJ
fnp-5842	1	81	neuroanatomy	neuroanatomy	NOUN
fnp-5842	1	82	,	,	PUNCT
fnp-5842	1	83	dgnn	dgnn	NOUN
fnp-5842	1	84	,	,	PUNCT
fnp-5842	1	85	meeting	meet	VERB
fnp-5842	1	86	abstracts	abstract	NOUN
fnp-5842	1	87	dear	dear	ADJ
fnp-5842	1	88	colleagues	colleague	NOUN
fnp-5842	1	89	,	,	PUNCT
fnp-5842	1	90	it	it	PRON
fnp-5842	1	91	is	be	AUX
fnp-5842	1	92	my	my	PRON
fnp-5842	1	93	pleasure	pleasure	NOUN
fnp-5842	1	94	and	and	CCONJ
fnp-5842	1	95	honor	honor	NOUN
fnp-5842	1	96	to	to	PART
fnp-5842	1	97	host	host	VERB
fnp-5842	1	98	the	the	DET
fnp-5842	1	99	68th	68th	ADJ
fnp-5842	1	100	annual	annual	ADJ
fnp-5842	1	101	meeting	meeting	NOUN
fnp-5842	1	102	of	of	ADP
fnp-5842	1	103	the	the	DET
fnp-5842	1	104	german	german	ADJ
fnp-5842	1	105	society	society	NOUN
fnp-5842	1	106	of	of	ADP
fnp-5842	1	107	neuropathology	neuropathology	NOUN
fnp-5842	1	108	and	and	CCONJ
fnp-5842	1	109	neuroanatomy	neuroanatomy	NOUN
fnp-5842	1	110	(	(	PUNCT
fnp-5842	1	111	dgnn	dgnn	NOUN
fnp-5842	1	112	)	)	PUNCT
fnp-5842	1	113	in	in	ADP
fnp-5842	1	114	regensburg	regensburg	PROPN
fnp-5842	1	115	.	.	PUNCT
fnp-5842	2	1	since	since	SCONJ
fnp-5842	2	2	the	the	DET
fnp-5842	2	3	magdeburg	magdeburg	PROPN
fnp-5842	2	4	meeting	meeting	NOUN
fnp-5842	2	5	in	in	ADP
fnp-5842	2	6	2019	2019	NUM
fnp-5842	2	7	this	this	PRON
fnp-5842	2	8	is	be	AUX
fnp-5842	2	9	the	the	DET
fnp-5842	2	10	first	first	ADJ
fnp-5842	2	11	pure	pure	ADJ
fnp-5842	2	12	national	national	ADJ
fnp-5842	2	13	meeting	meeting	NOUN
fnp-5842	2	14	of	of	ADP
fnp-5842	2	15	our	our	PRON
fnp-5842	2	16	society	society	NOUN
fnp-5842	2	17	that	that	PRON
fnp-5842	2	18	will	will	AUX
fnp-5842	2	19	be	be	AUX
fnp-5842	2	20	held	hold	VERB
fnp-5842	2	21	in	in	ADP
fnp-5842	2	22	presence	presence	NOUN
fnp-5842	2	23	after	after	ADP
fnp-5842	2	24	five	five	NUM
fnp-5842	2	25	long	long	ADJ
fnp-5842	2	26	years	year	NOUN
fnp-5842	2	27	.	.	PUNCT
fnp-5842	3	1	while	while	SCONJ
fnp-5842	3	2	the	the	DET
fnp-5842	3	3	meeting	meeting	NOUN
fnp-5842	3	4	in	in	ADP
fnp-5842	3	5	2020	2020	NUM
fnp-5842	3	6	was	be	AUX
fnp-5842	3	7	cancelled	cancel	VERB
fnp-5842	3	8	due	due	ADP
fnp-5842	3	9	to	to	ADP
fnp-5842	3	10	the	the	DET
fnp-5842	3	11	corona	corona	NOUN
fnp-5842	3	12	pandemic	pandemic	NOUN
fnp-5842	3	13	,	,	PUNCT
fnp-5842	3	14	the	the	DET
fnp-5842	3	15	2021	2021	NUM
fnp-5842	3	16	meeting	meeting	NOUN
fnp-5842	3	17	(	(	PUNCT
fnp-5842	3	18	organized	organize	VERB
fnp-5842	3	19	by	by	ADP
fnp-5842	3	20	the	the	DET
fnp-5842	3	21	colleagues	colleague	NOUN
fnp-5842	3	22	in	in	ADP
fnp-5842	3	23	gießen	gießen	NOUN
fnp-5842	3	24	)	)	PUNCT
fnp-5842	3	25	took	take	VERB
fnp-5842	3	26	place	place	NOUN
fnp-5842	3	27	as	as	ADP
fnp-5842	3	28	a	a	DET
fnp-5842	3	29	mere	mere	ADJ
fnp-5842	3	30	online	online	ADJ
fnp-5842	3	31	meeting	meeting	NOUN
fnp-5842	3	32	.	.	PUNCT
fnp-5842	4	1	in	in	ADP
fnp-5842	4	2	2022	2022	NUM
fnp-5842	4	3	and	and	CCONJ
fnp-5842	4	4	2023	2023	NUM
fnp-5842	4	5	our	our	PRON
fnp-5842	4	6	national	national	ADJ
fnp-5842	4	7	society	society	NOUN
fnp-5842	4	8	meetings	meeting	NOUN
fnp-5842	4	9	were	be	AUX
fnp-5842	4	10	embedded	embed	VERB
fnp-5842	4	11	in	in	ADP
fnp-5842	4	12	the	the	DET
fnp-5842	4	13	“	"	PUNCT
fnp-5842	4	14	neurowoche	neurowoche	NOUN
fnp-5842	4	15	”	"	PUNCT
fnp-5842	4	16	and	and	CCONJ
fnp-5842	4	17	the	the	DET
fnp-5842	4	18	international	international	ADJ
fnp-5842	4	19	congress	congress	PROPN
fnp-5842	4	20	of	of	ADP
fnp-5842	4	21	neuropathology	neuropathology	NOUN
fnp-5842	4	22	in	in	ADP
fnp-5842	4	23	berlin	berlin	PROPN
fnp-5842	4	24	.	.	PUNCT
fnp-5842	5	1	we	we	PRON
fnp-5842	5	2	are	be	AUX
fnp-5842	5	3	enthusiastic	enthusiastic	ADJ
fnp-5842	5	4	about	about	ADP
fnp-5842	5	5	this	this	DET
fnp-5842	5	6	years	year	NOUN
fnp-5842	5	7	’	'	PUNCT
fnp-5842	5	8	reunion	reunion	NOUN
fnp-5842	5	9	of	of	ADP
fnp-5842	5	10	our	our	PRON
fnp-5842	5	11	society	society	NOUN
fnp-5842	5	12	in	in	ADP
fnp-5842	5	13	regensburg	regensburg	PROPN
fnp-5842	5	14	.	.	PUNCT
fnp-5842	6	1	in	in	ADP
fnp-5842	6	2	our	our	PRON
fnp-5842	6	3	regensburg	regensburg	PROPN
fnp-5842	6	4	meeting	meeting	NOUN
fnp-5842	6	5	,	,	PUNCT
fnp-5842	6	6	we	we	PRON
fnp-5842	6	7	aim	aim	VERB
fnp-5842	6	8	to	to	PART
fnp-5842	6	9	provide	provide	VERB
fnp-5842	6	10	a	a	DET
fnp-5842	6	11	comprehensive	comprehensive	ADJ
fnp-5842	6	12	update	update	NOUN
fnp-5842	6	13	on	on	ADP
fnp-5842	6	14	the	the	DET
fnp-5842	6	15	major	major	ADJ
fnp-5842	6	16	and	and	CCONJ
fnp-5842	6	17	hot	hot	ADJ
fnp-5842	6	18	topics	topic	NOUN
fnp-5842	6	19	in	in	ADP
fnp-5842	6	20	neuropathology	neuropathology	NOUN
fnp-5842	6	21	.	.	PUNCT
fnp-5842	7	1	neuropathologists	neuropathologist	NOUN
fnp-5842	7	2	address	address	VERB
fnp-5842	7	3	some	some	PRON
fnp-5842	7	4	of	of	ADP
fnp-5842	7	5	the	the	DET
fnp-5842	7	6	currently	currently	ADV
fnp-5842	7	7	most	most	ADV
fnp-5842	7	8	relevant	relevant	ADJ
fnp-5842	7	9	and	and	CCONJ
fnp-5842	7	10	discussed	discuss	VERB
fnp-5842	7	11	health	health	NOUN
fnp-5842	7	12	care	care	NOUN
fnp-5842	7	13	issues	issue	NOUN
fnp-5842	7	14	,	,	PUNCT
fnp-5842	7	15	such	such	ADJ
fnp-5842	7	16	as	as	ADP
fnp-5842	7	17	for	for	ADP
fnp-5842	7	18	example	example	NOUN
fnp-5842	7	19	cancer	cancer	NOUN
fnp-5842	7	20	,	,	PUNCT
fnp-5842	7	21	neuroimmunological	neuroimmunological	ADJ
fnp-5842	7	22	diseases	disease	NOUN
fnp-5842	7	23	like	like	ADP
fnp-5842	7	24	multiple	multiple	ADJ
fnp-5842	7	25	sclerosis	sclerosis	NOUN
fnp-5842	7	26	,	,	PUNCT
fnp-5842	7	27	neurodegenerative	neurodegenerative	ADJ
fnp-5842	7	28	diseases	disease	NOUN
fnp-5842	7	29	including	include	VERB
fnp-5842	7	30	alzheimer	alzheimer	PROPN
fnp-5842	7	31	’s	’s	PART
fnp-5842	7	32	and	and	CCONJ
fnp-5842	7	33	parkinson	parkinson	NOUN
fnp-5842	7	34	’s	’s	PART
fnp-5842	7	35	,	,	PUNCT
fnp-5842	7	36	and	and	CCONJ
fnp-5842	7	37	muscle	muscle	NOUN
fnp-5842	7	38	/	/	SYM
fnp-5842	7	39	nerve	nerve	NOUN
fnp-5842	7	40	diseases	disease	NOUN
fnp-5842	7	41	.	.	PUNCT
fnp-5842	8	1	as	as	ADP
fnp-5842	8	2	tissue	tissue	NOUN
fnp-5842	8	3	specialists	specialist	NOUN
fnp-5842	8	4	,	,	PUNCT
fnp-5842	8	5	neuropathologists	neuropathologist	NOUN
fnp-5842	8	6	directly	directly	ADV
fnp-5842	8	7	study	study	VERB
fnp-5842	8	8	diseases	disease	NOUN
fnp-5842	8	9	in	in	ADP
fnp-5842	8	10	human	human	ADJ
fnp-5842	8	11	materials	material	NOUN
fnp-5842	8	12	.	.	PUNCT
fnp-5842	9	1	neuropathologists	neuropathologist	NOUN
fnp-5842	9	2	use	use	VERB
fnp-5842	9	3	state	state	NOUN
fnp-5842	9	4	of	of	ADP
fnp-5842	9	5	-	-	PUNCT
fnp-5842	9	6	the	the	DET
fnp-5842	9	7	-	-	PUNCT
fnp-5842	9	8	art	art	NOUN
fnp-5842	9	9	methods	method	NOUN
fnp-5842	9	10	to	to	PART
fnp-5842	9	11	uncover	uncover	VERB
fnp-5842	9	12	disease	disease	NOUN
fnp-5842	9	13	processes	process	NOUN
fnp-5842	9	14	on	on	ADP
fnp-5842	9	15	the	the	DET
fnp-5842	9	16	molecular	molecular	ADJ
fnp-5842	9	17	level	level	NOUN
fnp-5842	9	18	.	.	PUNCT
fnp-5842	10	1	during	during	ADP
fnp-5842	10	2	our	our	PRON
fnp-5842	10	3	congress	congress	NOUN
fnp-5842	10	4	,	,	PUNCT
fnp-5842	10	5	we	we	PRON
fnp-5842	10	6	will	will	AUX
fnp-5842	10	7	hear	hear	VERB
fnp-5842	10	8	a	a	DET
fnp-5842	10	9	lot	lot	NOUN
fnp-5842	10	10	on	on	ADP
fnp-5842	10	11	the	the	DET
fnp-5842	10	12	methodical	methodical	ADJ
fnp-5842	10	13	progress	progress	NOUN
fnp-5842	10	14	made	make	VERB
fnp-5842	10	15	in	in	ADP
fnp-5842	10	16	this	this	DET
fnp-5842	10	17	regard	regard	NOUN
fnp-5842	10	18	.	.	PUNCT
fnp-5842	11	1	neuropathology	neuropathology	NOUN
fnp-5842	11	2	is	be	AUX
fnp-5842	11	3	also	also	ADV
fnp-5842	11	4	becoming	become	VERB
fnp-5842	11	5	increasingly	increasingly	ADV
fnp-5842	11	6	clinical	clinical	ADJ
fnp-5842	11	7	as	as	ADP
fnp-5842	11	8	many	many	ADJ
fnp-5842	11	9	of	of	ADP
fnp-5842	11	10	our	our	PRON
fnp-5842	11	11	scientific	scientific	ADJ
fnp-5842	11	12	and	and	CCONJ
fnp-5842	11	13	diagnostic	diagnostic	ADJ
fnp-5842	11	14	findings	finding	NOUN
fnp-5842	11	15	influence	influence	NOUN
fnp-5842	11	16	and	and	CCONJ
fnp-5842	11	17	directly	directly	ADV
fnp-5842	11	18	guide	guide	VERB
fnp-5842	11	19	treatment	treatment	NOUN
fnp-5842	11	20	decisions	decision	NOUN
fnp-5842	11	21	.	.	PUNCT
fnp-5842	12	1	we	we	PRON
fnp-5842	12	2	were	be	AUX
fnp-5842	12	3	able	able	ADJ
fnp-5842	12	4	to	to	PART
fnp-5842	12	5	attract	attract	VERB
fnp-5842	12	6	renowned	renowned	ADJ
fnp-5842	12	7	national	national	ADJ
fnp-5842	12	8	and	and	CCONJ
fnp-5842	12	9	international	international	ADJ
fnp-5842	12	10	speakers	speaker	NOUN
fnp-5842	12	11	and	and	CCONJ
fnp-5842	12	12	our	our	PRON
fnp-5842	12	13	meeting	meeting	NOUN
fnp-5842	12	14	will	will	AUX
fnp-5842	12	15	allow	allow	VERB
fnp-5842	12	16	for	for	ADP
fnp-5842	12	17	an	an	DET
fnp-5842	12	18	intensive	intensive	ADJ
fnp-5842	12	19	interchange	interchange	NOUN
fnp-5842	12	20	both	both	CCONJ
fnp-5842	12	21	within	within	ADP
fnp-5842	12	22	our	our	PRON
fnp-5842	12	23	society	society	NOUN
fnp-5842	12	24	and	and	CCONJ
fnp-5842	12	25	with	with	ADP
fnp-5842	12	26	our	our	PRON
fnp-5842	12	27	neighboring	neighboring	NOUN
fnp-5842	12	28	disciplines	discipline	NOUN
fnp-5842	12	29	.	.	PUNCT
fnp-5842	13	1	program	program	NOUN
fnp-5842	13	2	highlights	highlight	NOUN
fnp-5842	13	3	include	include	VERB
fnp-5842	13	4	a	a	DET
fnp-5842	13	5	pre	pre	ADJ
fnp-5842	13	6	-	-	ADJ
fnp-5842	13	7	congress	congress	ADJ
fnp-5842	13	8	hands	hand	NOUN
fnp-5842	13	9	-	-	PUNCT
fnp-5842	13	10	on	on	ADP
fnp-5842	13	11	workshop	workshop	NOUN
fnp-5842	13	12	on	on	ADP
fnp-5842	13	13	next	next	ADJ
fnp-5842	13	14	generation	generation	NOUN
fnp-5842	13	15	sequencing	sequence	VERB
fnp-5842	13	16	,	,	PUNCT
fnp-5842	13	17	a	a	DET
fnp-5842	13	18	session	session	NOUN
fnp-5842	13	19	on	on	ADP
fnp-5842	13	20	molecular	molecular	ADJ
fnp-5842	13	21	tumorboards	tumorboard	NOUN
fnp-5842	13	22	and	and	CCONJ
fnp-5842	13	23	a	a	DET
fnp-5842	13	24	mini	mini	NOUN
fnp-5842	13	25	-	-	NOUN
fnp-5842	13	26	symposium	symposium	NOUN
fnp-5842	13	27	on	on	ADP
fnp-5842	13	28	quality	quality	NOUN
fnp-5842	13	29	assurance	assurance	NOUN
fnp-5842	13	30	in	in	ADP
fnp-5842	13	31	neuropathology	neuropathology	NOUN
fnp-5842	13	32	.	.	PUNCT
fnp-5842	14	1	we	we	PRON
fnp-5842	14	2	are	be	AUX
fnp-5842	14	3	delighted	delighted	ADJ
fnp-5842	14	4	about	about	ADP
fnp-5842	14	5	the	the	DET
fnp-5842	14	6	submission	submission	NOUN
fnp-5842	14	7	of	of	ADP
fnp-5842	14	8	31	31	NUM
fnp-5842	14	9	abstracts	abstract	NOUN
fnp-5842	14	10	covering	cover	VERB
fnp-5842	14	11	the	the	DET
fnp-5842	14	12	research	research	NOUN
fnp-5842	14	13	fields	field	NOUN
fnp-5842	14	14	neurooncology	neurooncology	NOUN
fnp-5842	14	15	,	,	PUNCT
fnp-5842	14	16	neuroimmunology	neuroimmunology	NOUN
fnp-5842	14	17	,	,	PUNCT
fnp-5842	14	18	muscle	muscle	NOUN
fnp-5842	14	19	/	/	SYM
fnp-5842	14	20	nerve	nerve	NOUN
fnp-5842	14	21	,	,	PUNCT
fnp-5842	14	22	neurodegeneration	neurodegeneration	NOUN
fnp-5842	14	23	,	,	PUNCT
fnp-5842	14	24	and	and	CCONJ
fnp-5842	14	25	methods	method	NOUN
fnp-5842	14	26	/	/	SYM
fnp-5842	14	27	free	free	ADJ
fnp-5842	14	28	topics	topic	NOUN
fnp-5842	14	29	.	.	PUNCT
fnp-5842	15	1	the	the	DET
fnp-5842	15	2	abstracts	abstract	NOUN
fnp-5842	15	3	are	be	AUX
fnp-5842	15	4	published	publish	VERB
fnp-5842	15	5	below	below	ADP
fnp-5842	15	6	in	in	ADP
fnp-5842	15	7	this	this	DET
fnp-5842	15	8	edition	edition	NOUN
fnp-5842	15	9	of	of	ADP
fnp-5842	15	10	free	free	ADJ
fnp-5842	15	11	neuropathology	neuropathology	NOUN
fnp-5842	15	12	.	.	PUNCT
fnp-5842	16	1	i	i	PRON
fnp-5842	16	2	want	want	VERB
fnp-5842	16	3	to	to	PART
fnp-5842	16	4	thank	thank	VERB
fnp-5842	16	5	the	the	DET
fnp-5842	16	6	scientific	scientific	ADJ
fnp-5842	16	7	committee	committee	NOUN
fnp-5842	16	8	of	of	ADP
fnp-5842	16	9	our	our	PRON
fnp-5842	16	10	congress	congress	PROPN
fnp-5842	16	11	for	for	ADP
fnp-5842	16	12	helping	help	VERB
fnp-5842	16	13	in	in	ADP
fnp-5842	16	14	evaluating	evaluate	VERB
fnp-5842	16	15	the	the	DET
fnp-5842	16	16	submissions	submission	NOUN
fnp-5842	16	17	and	and	CCONJ
fnp-5842	16	18	selecting	select	VERB
fnp-5842	16	19	the	the	DET
fnp-5842	16	20	poster	poster	NOUN
fnp-5842	16	21	talks	talk	NOUN
fnp-5842	16	22	and	and	CCONJ
fnp-5842	16	23	poster	poster	NOUN
fnp-5842	16	24	spotlight	spotlight	NOUN
fnp-5842	16	25	presentations	presentation	NOUN
fnp-5842	16	26	.	.	PUNCT
fnp-5842	17	1	many	many	ADJ
fnp-5842	17	2	of	of	ADP
fnp-5842	17	3	the	the	DET
fnp-5842	17	4	abstracts	abstract	NOUN
fnp-5842	17	5	were	be	AUX
fnp-5842	17	6	submitted	submit	VERB
fnp-5842	17	7	by	by	ADP
fnp-5842	17	8	our	our	PRON
fnp-5842	17	9	young	young	ADJ
fnp-5842	17	10	researchers	researcher	NOUN
fnp-5842	17	11	.	.	PUNCT
fnp-5842	18	1	they	they	PRON
fnp-5842	18	2	deserve	deserve	VERB
fnp-5842	18	3	our	our	PRON
fnp-5842	18	4	special	special	ADJ
fnp-5842	18	5	attention	attention	NOUN
fnp-5842	18	6	!	!	PUNCT
fnp-5842	19	1	posters	poster	NOUN
fnp-5842	19	2	will	will	AUX
fnp-5842	19	3	be	be	AUX
fnp-5842	19	4	exhibited	exhibit	VERB
fnp-5842	19	5	throughout	throughout	ADP
fnp-5842	19	6	the	the	DET
fnp-5842	19	7	entire	entire	ADJ
fnp-5842	19	8	congress	congress	NOUN
fnp-5842	19	9	and	and	CCONJ
fnp-5842	19	10	we	we	PRON
fnp-5842	19	11	will	will	AUX
fnp-5842	19	12	have	have	VERB
fnp-5842	19	13	plenty	plenty	NOUN
fnp-5842	19	14	of	of	ADP
fnp-5842	19	15	time	time	NOUN
fnp-5842	19	16	for	for	ADP
fnp-5842	19	17	poster	poster	NOUN
fnp-5842	19	18	viewing	viewing	NOUN
fnp-5842	19	19	and	and	CCONJ
fnp-5842	19	20	discussions	discussion	NOUN
fnp-5842	19	21	on	on	ADP
fnp-5842	19	22	thursday	thursday	PROPN
fnp-5842	19	23	evening	evening	NOUN
fnp-5842	19	24	at	at	ADP
fnp-5842	19	25	the	the	DET
fnp-5842	19	26	welcome	welcome	ADJ
fnp-5842	19	27	reception	reception	NOUN
fnp-5842	19	28	and	and	CCONJ
fnp-5842	19	29	at	at	ADP
fnp-5842	19	30	the	the	DET
fnp-5842	19	31	main	main	ADJ
fnp-5842	19	32	poster	poster	NOUN
fnp-5842	19	33	session	session	NOUN
fnp-5842	19	34	on	on	ADP
fnp-5842	19	35	friday	friday	PROPN
fnp-5842	19	36	at	at	ADP
fnp-5842	19	37	noon	noon	NOUN
fnp-5842	19	38	.	.	PUNCT
fnp-5842	20	1	so	so	ADV
fnp-5842	20	2	let	let	VERB
fnp-5842	20	3	me	i	PRON
fnp-5842	20	4	again	again	ADV
fnp-5842	20	5	welcome	welcome	VERB
fnp-5842	20	6	you	you	PRON
fnp-5842	20	7	all	all	PRON
fnp-5842	20	8	to	to	ADP
fnp-5842	20	9	our	our	PRON
fnp-5842	20	10	beautiful	beautiful	ADJ
fnp-5842	20	11	city	city	NOUN
fnp-5842	20	12	of	of	ADP
fnp-5842	20	13	regensburg	regensburg	PROPN
fnp-5842	20	14	.	.	PUNCT
fnp-5842	21	1	i	i	PRON
fnp-5842	21	2	am	be	AUX
fnp-5842	21	3	looking	look	VERB
fnp-5842	21	4	forward	forward	ADV
fnp-5842	21	5	to	to	ADP
fnp-5842	21	6	inspiring	inspiring	ADJ
fnp-5842	21	7	talks	talk	NOUN
fnp-5842	21	8	,	,	PUNCT
fnp-5842	21	9	vivid	vivid	ADJ
fnp-5842	21	10	discussions	discussion	NOUN
fnp-5842	21	11	and	and	CCONJ
fnp-5842	21	12	enriching	enrich	VERB
fnp-5842	21	13	encounters	encounter	NOUN
fnp-5842	21	14	with	with	ADP
fnp-5842	21	15	like	like	ADJ
fnp-5842	21	16	-	-	PUNCT
fnp-5842	21	17	minded	minded	ADJ
fnp-5842	21	18	people	people	NOUN
fnp-5842	21	19	.	.	PUNCT
fnp-5842	22	1	yours	yours	PRON
fnp-5842	22	2	,	,	PUNCT
fnp-5842	22	3	prof	prof	PROPN
fnp-5842	22	4	.	.	PUNCT
fnp-5842	23	1	dr	dr	PROPN
fnp-5842	23	2	.	.	PROPN
fnp-5842	23	3	markus	markus	PROPN
fnp-5842	23	4	j.	j.	PROPN
fnp-5842	23	5	riemenschneider	riemenschneider	PROPN
fnp-5842	23	6	regensburg	regensburg	PROPN
fnp-5842	23	7	university	university	PROPN
fnp-5842	23	8	hospital	hospital	NOUN
fnp-5842	23	9	,	,	PUNCT
fnp-5842	23	10	department	department	NOUN
fnp-5842	23	11	of	of	ADP
fnp-5842	23	12	neuropathology	neuropathology	PROPN
fnp-5842	23	13	congress	congress	PROPN
fnp-5842	23	14	president	president	PROPN
fnp-5842	23	15	dgnn	dgnn	PROPN
fnp-5842	23	16	annual	annual	ADJ
fnp-5842	23	17	meeting	meeting	NOUN
fnp-5842	23	18	2024	2024	NUM
fnp-5842	23	19	contents	content	NOUN
fnp-5842	23	20	i.	i.	PROPN
fnp-5842	23	21	neurooncology	neurooncology	PROPN
fnp-5842	23	22	p01	p01	NOUN
fnp-5842	23	23	identification	identification	NOUN
fnp-5842	23	24	and	and	CCONJ
fnp-5842	23	25	description	description	NOUN
fnp-5842	23	26	of	of	ADP
fnp-5842	23	27	a	a	DET
fnp-5842	23	28	novel	novel	ADJ
fnp-5842	23	29	type	type	NOUN
fnp-5842	23	30	of	of	ADP
fnp-5842	23	31	medulloblastoma	medulloblastoma	NOUN
fnp-5842	23	32	p02	p02	X
fnp-5842	23	33	glutamatergic	glutamatergic	ADJ
fnp-5842	23	34	synaptic	synaptic	ADJ
fnp-5842	23	35	input	input	NOUN
fnp-5842	23	36	to	to	ADP
fnp-5842	23	37	brain	brain	NOUN
fnp-5842	23	38	metastases	metastasis	NOUN
fnp-5842	23	39	drives	drive	VERB
fnp-5842	23	40	metastatic	metastatic	ADJ
fnp-5842	23	41	colonization	colonization	NOUN
fnp-5842	23	42	p03	p03	PROPN
fnp-5842	23	43	brain	brain	NOUN
fnp-5842	23	44	invasion	invasion	NOUN
fnp-5842	23	45	in	in	ADP
fnp-5842	23	46	otherwise	otherwise	ADV
fnp-5842	23	47	benign	benign	ADJ
fnp-5842	23	48	meningiomas	meningioma	NOUN
fnp-5842	23	49	:	:	PUNCT
fnp-5842	23	50	molecular	molecular	ADJ
fnp-5842	23	51	characteristics	characteristic	NOUN
fnp-5842	23	52	and	and	CCONJ
fnp-5842	23	53	prognostic	prognostic	ADJ
fnp-5842	23	54	relevance	relevance	NOUN
fnp-5842	23	55	p04	p04	PROPN
fnp-5842	23	56	electrophysiological	electrophysiological	ADJ
fnp-5842	23	57	characterization	characterization	NOUN
fnp-5842	23	58	of	of	ADP
fnp-5842	23	59	slow	slow	ADJ
fnp-5842	23	60	inward	inward	ADJ
fnp-5842	23	61	currents	current	NOUN
fnp-5842	23	62	in	in	ADP
fnp-5842	23	63	glioblastoma	glioblastoma	NOUN
fnp-5842	23	64	p05	p05	VERB
fnp-5842	23	65	nanopore	nanopore	ADV
fnp-5842	23	66	sequencing	sequence	VERB
fnp-5842	23	67	from	from	ADP
fnp-5842	23	68	formalin	formalin	NOUN
fnp-5842	23	69	-	-	PUNCT
fnp-5842	23	70	fixed	fix	VERB
fnp-5842	23	71	paraffin	paraffin	NOUN
fnp-5842	23	72	-	-	PUNCT
fnp-5842	23	73	embedded	embed	VERB
fnp-5842	23	74	specimens	specimen	NOUN
fnp-5842	23	75	for	for	ADP
fnp-5842	23	76	copy	copy	NOUN
fnp-5842	23	77	number	number	NOUN
fnp-5842	23	78	profiling	profiling	NOUN
fnp-5842	23	79	and	and	CCONJ
fnp-5842	23	80	methylation	methylation	NOUN
fnp-5842	23	81	-	-	PUNCT
fnp-5842	23	82	based	base	VERB
fnp-5842	23	83	cns	cns	NOUN
fnp-5842	23	84	tumor	tumor	NOUN
fnp-5842	23	85	classification	classification	NOUN
fnp-5842	23	86	p06	p06	ADJ
fnp-5842	23	87	epigenetic	epigenetic	ADJ
fnp-5842	23	88	profiling	profiling	NOUN
fnp-5842	23	89	can	can	AUX
fnp-5842	23	90	improve	improve	VERB
fnp-5842	23	91	diagnostics	diagnostic	NOUN
fnp-5842	23	92	of	of	ADP
fnp-5842	23	93	mpnst	mpnst	NOUN
fnp-5842	23	94	with	with	ADP
fnp-5842	23	95	intratumoral	intratumoral	ADJ
fnp-5842	23	96	histological	histological	ADJ
fnp-5842	23	97	heterogeneity	heterogeneity	NOUN
fnp-5842	23	98	p07	p07	NOUN
fnp-5842	23	99	anaplastic	anaplastic	ADJ
fnp-5842	23	100	histology	histology	NOUN
fnp-5842	23	101	and	and	CCONJ
fnp-5842	23	102	distinct	distinct	ADJ
fnp-5842	23	103	molecular	molecular	ADJ
fnp-5842	23	104	features	feature	NOUN
fnp-5842	23	105	in	in	ADP
fnp-5842	23	106	a	a	DET
fnp-5842	23	107	small	small	ADJ
fnp-5842	23	108	series	series	NOUN
fnp-5842	23	109	of	of	ADP
fnp-5842	23	110	spinal	spinal	PROPN
fnp-5842	23	111	cord	cord	NOUN
fnp-5842	23	112	ependymomas	ependymomas	PROPN
fnp-5842	23	113	p08	p08	PROPN
fnp-5842	23	114	integrated	integrate	VERB
fnp-5842	23	115	analyses	analysis	NOUN
fnp-5842	23	116	reveal	reveal	VERB
fnp-5842	23	117	two	two	NUM
fnp-5842	23	118	molecularly	molecularly	ADV
fnp-5842	23	119	and	and	CCONJ
fnp-5842	23	120	clinically	clinically	ADV
fnp-5842	23	121	distinct	distinct	ADJ
fnp-5842	23	122	subtypes	subtype	NOUN
fnp-5842	23	123	of	of	ADP
fnp-5842	23	124	h3	h3	NOUN
fnp-5842	23	125	k27m	k27m	NOUN
fnp-5842	23	126	-	-	ADJ
fnp-5842	23	127	mutant	mutant	ADJ
fnp-5842	23	128	diffuse	diffuse	NOUN
fnp-5842	23	129	midline	midline	NOUN
fnp-5842	23	130	gliomas	glioma	NOUN
fnp-5842	23	131	with	with	ADP
fnp-5842	23	132	prognostic	prognostic	ADJ
fnp-5842	23	133	significance	significance	NOUN
fnp-5842	23	134	p09	p09	NOUN
fnp-5842	23	135	spatial	spatial	ADJ
fnp-5842	23	136	multiomics	multiomics	NOUN
fnp-5842	23	137	profiling	profiling	NOUN
fnp-5842	23	138	reveals	reveal	VERB
fnp-5842	23	139	heterogeneity	heterogeneity	NOUN
fnp-5842	23	140	of	of	ADP
fnp-5842	23	141	b	b	NOUN
fnp-5842	23	142	:	:	PUNCT
fnp-5842	23	143	t	t	NOUN
fnp-5842	23	144	cell	cell	NOUN
fnp-5842	23	145	interactions	interaction	NOUN
fnp-5842	23	146	and	and	CCONJ
fnp-5842	23	147	plasma	plasma	NOUN
fnp-5842	23	148	cell	cell	NOUN
fnp-5842	23	149	formation	formation	NOUN
fnp-5842	23	150	in	in	ADP
fnp-5842	23	151	tertiary	tertiary	ADJ
fnp-5842	23	152	lymphoid	lymphoid	NOUN
fnp-5842	23	153	structures	structure	NOUN
fnp-5842	23	154	in	in	ADP
fnp-5842	23	155	human	human	ADJ
fnp-5842	23	156	gliomas	glioma	NOUN
fnp-5842	23	157	p10	p10	ADJ
fnp-5842	23	158	digital	digital	ADJ
fnp-5842	23	159	biomarkers	biomarker	NOUN
fnp-5842	23	160	for	for	ADP
fnp-5842	23	161	an	an	DET
fnp-5842	23	162	improved	improve	VERB
fnp-5842	23	163	clinical	clinical	ADJ
fnp-5842	23	164	stratification	stratification	NOUN
fnp-5842	23	165	of	of	ADP
fnp-5842	23	166	meningioma	meningioma	NOUN
fnp-5842	23	167	patients	patient	NOUN
fnp-5842	23	168	p11	p11	VERB
fnp-5842	23	169	cellular	cellular	ADJ
fnp-5842	23	170	senescence	senescence	NOUN
fnp-5842	23	171	as	as	ADP
fnp-5842	23	172	a	a	DET
fnp-5842	23	173	shared	share	VERB
fnp-5842	23	174	contributor	contributor	NOUN
fnp-5842	23	175	to	to	PART
fnp-5842	23	176	disease	disease	NOUN
fnp-5842	23	177	progression	progression	NOUN
fnp-5842	23	178	in	in	ADP
fnp-5842	23	179	glioblastoma	glioblastoma	NOUN
fnp-5842	23	180	and	and	CCONJ
fnp-5842	23	181	alzheimer	alzheimer	PROPN
fnp-5842	23	182	's	's	PART
fnp-5842	23	183	disease	disease	NOUN
fnp-5842	23	184	p12	p12	NOUN
fnp-5842	23	185	vopp1::egfr	vopp1::egfr	NOUN
fnp-5842	23	186	gene	gene	NOUN
fnp-5842	23	187	fusion	fusion	NOUN
fnp-5842	23	188	as	as	ADP
fnp-5842	23	189	an	an	DET
fnp-5842	23	190	oncogenic	oncogenic	ADJ
fnp-5842	23	191	driver	driver	NOUN
fnp-5842	23	192	via	via	ADP
fnp-5842	23	193	nfκb	nfκb	ADJ
fnp-5842	23	194	pathway	pathway	NOUN
fnp-5842	23	195	activation	activation	NOUN
fnp-5842	23	196	in	in	ADP
fnp-5842	23	197	a	a	DET
fnp-5842	23	198	case	case	NOUN
fnp-5842	23	199	of	of	ADP
fnp-5842	23	200	ganglioglioma	ganglioglioma	ADJ
fnp-5842	23	201	p13	p13	NOUN
fnp-5842	23	202	insights	insight	NOUN
fnp-5842	23	203	from	from	ADP
fnp-5842	23	204	the	the	DET
fnp-5842	23	205	additional	additional	ADJ
fnp-5842	23	206	immunohistochemical	immunohistochemical	ADJ
fnp-5842	23	207	work	work	NOUN
fnp-5842	23	208	-	-	PUNCT
fnp-5842	23	209	up	up	NOUN
fnp-5842	23	210	of	of	ADP
fnp-5842	23	211	molecular	molecular	ADJ
fnp-5842	23	212	tumor	tumor	NOUN
fnp-5842	23	213	board	board	NOUN
fnp-5842	23	214	patients	patient	NOUN
fnp-5842	23	215	from	from	ADP
fnp-5842	23	216	a	a	DET
fnp-5842	23	217	regional	regional	ADJ
fnp-5842	23	218	brain	brain	NOUN
fnp-5842	23	219	tumor	tumor	NOUN
fnp-5842	23	220	center	center	NOUN
fnp-5842	23	221	p14	p14	VERB
fnp-5842	23	222	cytokine	cytokine	ADJ
fnp-5842	23	223	response	response	NOUN
fnp-5842	23	224	in	in	ADP
fnp-5842	23	225	the	the	DET
fnp-5842	23	226	cerebrospinal	cerebrospinal	ADJ
fnp-5842	23	227	fluid	fluid	NOUN
fnp-5842	23	228	after	after	ADP
fnp-5842	23	229	intraoperative	intraoperative	ADJ
fnp-5842	23	230	radiation	radiation	NOUN
fnp-5842	23	231	of	of	ADP
fnp-5842	23	232	primary	primary	ADJ
fnp-5842	23	233	and	and	CCONJ
fnp-5842	23	234	metastatic	metastatic	ADJ
fnp-5842	23	235	brain	brain	NOUN
fnp-5842	23	236	tumors	tumor	NOUN
fnp-5842	23	237	ii	ii	PROPN
fnp-5842	23	238	.	.	PUNCT
fnp-5842	24	1	neuroimmunology	neuroimmunology	PROPN
fnp-5842	24	2	p15	p15	NOUN
fnp-5842	24	3	in	in	ADP
fnp-5842	24	4	-	-	PUNCT
fnp-5842	24	5	depth	depth	NOUN
fnp-5842	24	6	analysis	analysis	NOUN
fnp-5842	24	7	of	of	ADP
fnp-5842	24	8	viral	viral	ADJ
fnp-5842	24	9	distribution	distribution	NOUN
fnp-5842	24	10	and	and	CCONJ
fnp-5842	24	11	immunological	immunological	ADJ
fnp-5842	24	12	profiling	profiling	NOUN
fnp-5842	24	13	in	in	ADP
fnp-5842	24	14	human	human	ADJ
fnp-5842	24	15	bornavirus	bornavirus	NOUN
fnp-5842	24	16	encephalitis	encephalitis	NOUN
fnp-5842	24	17	p16	p16	NOUN
fnp-5842	24	18	histopathological	histopathological	ADJ
fnp-5842	24	19	analysis	analysis	NOUN
fnp-5842	24	20	of	of	ADP
fnp-5842	24	21	bodv-1	bodv-1	NOUN
fnp-5842	24	22	distribution	distribution	NOUN
fnp-5842	24	23	in	in	ADP
fnp-5842	24	24	a	a	DET
fnp-5842	24	25	non	non	ADJ
fnp-5842	24	26	-	-	ADJ
fnp-5842	24	27	human	human	ADJ
fnp-5842	24	28	primate	primate	NOUN
fnp-5842	24	29	model	model	NOUN
fnp-5842	24	30	:	:	PUNCT
fnp-5842	24	31	comparing	compare	VERB
fnp-5842	24	32	intranasal	intranasal	NOUN
fnp-5842	24	33	and	and	CCONJ
fnp-5842	24	34	subcutaneous	subcutaneous	ADJ
fnp-5842	24	35	inoculation	inoculation	NOUN
fnp-5842	24	36	p17	p17	NOUN
fnp-5842	24	37	systematic	systematic	ADJ
fnp-5842	24	38	analysis	analysis	NOUN
fnp-5842	24	39	of	of	ADP
fnp-5842	24	40	virus	virus	NOUN
fnp-5842	24	41	spread	spread	VERB
fnp-5842	24	42	to	to	ADP
fnp-5842	24	43	the	the	DET
fnp-5842	24	44	peripheral	peripheral	ADJ
fnp-5842	24	45	nervous	nervous	ADJ
fnp-5842	24	46	system	system	NOUN
fnp-5842	24	47	in	in	ADP
fnp-5842	24	48	fatal	fatal	ADJ
fnp-5842	24	49	borna	borna	PROPN
fnp-5842	24	50	virus	virus	PROPN
fnp-5842	24	51	encephalitis	encephalitis	PROPN
fnp-5842	24	52	p18	p18	ADJ
fnp-5842	24	53	global	global	ADJ
fnp-5842	24	54	cerebral	cerebral	ADJ
fnp-5842	24	55	hypoxia	hypoxia	NOUN
fnp-5842	24	56	-	-	PUNCT
fnp-5842	24	57	ischemia	ischemia	NOUN
fnp-5842	24	58	:	:	PUNCT
fnp-5842	24	59	ex	ex	X
fnp-5842	24	60	vivo	vivo	ADJ
fnp-5842	24	61	ultrahigh	ultrahigh	ADJ
fnp-5842	24	62	field	field	NOUN
fnp-5842	24	63	mri	mri	NOUN
fnp-5842	24	64	signals	signal	NOUN
fnp-5842	24	65	correlate	correlate	VERB
fnp-5842	24	66	with	with	ADP
fnp-5842	24	67	differential	differential	ADJ
fnp-5842	24	68	cortical	cortical	ADJ
fnp-5842	24	69	localization	localization	NOUN
fnp-5842	24	70	of	of	ADP
fnp-5842	24	71	microglia	microglia	NOUN
fnp-5842	24	72	and	and	CCONJ
fnp-5842	24	73	gemistocytes	gemistocyte	NOUN
fnp-5842	24	74	characterized	characterize	VERB
fnp-5842	24	75	by	by	ADP
fnp-5842	24	76	chit1	chit1	NOUN
fnp-5842	24	77	and	and	CCONJ
fnp-5842	24	78	chi3l1	chi3l1	NOUN
fnp-5842	24	79	(	(	PUNCT
fnp-5842	24	80	ykl	ykl	NOUN
fnp-5842	24	81	40	40	NUM
fnp-5842	24	82	)	)	PUNCT
fnp-5842	24	83	expression	expression	NOUN
fnp-5842	24	84	iii	iii	PROPN
fnp-5842	24	85	.	.	PUNCT
fnp-5842	24	86	muscle	muscle	NOUN
fnp-5842	24	87	/	/	SYM
fnp-5842	24	88	nerv	nerv	PROPN
fnp-5842	24	89	p19	p19	VERB
fnp-5842	24	90	adipo	adipo	NOUN
fnp-5842	24	91	-	-	PUNCT
fnp-5842	24	92	glial	glial	ADJ
fnp-5842	24	93	signaling	signal	VERB
fnp-5842	24	94	mediates	mediate	NOUN
fnp-5842	25	1	metabolic	metabolic	NOUN
fnp-5842	25	2	adaptation	adaptation	NOUN
fnp-5842	25	3	in	in	ADP
fnp-5842	25	4	peripheral	peripheral	ADJ
fnp-5842	25	5	nerve	nerve	NOUN
fnp-5842	25	6	regeneration	regeneration	NOUN
fnp-5842	25	7	iv	iv	PROPN
fnp-5842	25	8	.	.	PUNCT
fnp-5842	25	9	neurodegeneration	neurodegeneration	NOUN
fnp-5842	25	10	p20	p20	NOUN
fnp-5842	25	11	alpha	alpha	PROPN
fnp-5842	25	12	-	-	PUNCT
fnp-5842	25	13	synuclein	synuclein	NOUN
fnp-5842	25	14	co	co	NOUN
fnp-5842	25	15	-	-	NOUN
fnp-5842	25	16	pathology	pathology	NOUN
fnp-5842	25	17	in	in	ADP
fnp-5842	25	18	alzheimer	alzheimer	PROPN
fnp-5842	25	19	’s	’s	PART
fnp-5842	25	20	disease	disease	NOUN
fnp-5842	25	21	drives	drive	VERB
fnp-5842	25	22	tau	tau	PROPN
fnp-5842	25	23	accumulation	accumulation	NOUN
fnp-5842	25	24	p21	p21	NOUN
fnp-5842	25	25	frontotemporal	frontotemporal	ADJ
fnp-5842	25	26	dementia	dementia	NOUN
fnp-5842	25	27	patient	patient	NOUN
fnp-5842	25	28	neurons	neuron	NOUN
fnp-5842	25	29	with	with	ADP
fnp-5842	25	30	the	the	DET
fnp-5842	25	31	mapt	mapt	NOUN
fnp-5842	25	32	-	-	PUNCT
fnp-5842	25	33	n279k	n279k	NOUN
fnp-5842	25	34	mutation	mutation	NOUN
fnp-5842	25	35	are	be	AUX
fnp-5842	25	36	responsive	responsive	ADJ
fnp-5842	25	37	to	to	ADP
fnp-5842	25	38	tau	tau	PROPN
fnp-5842	25	39	filaments	filament	NOUN
fnp-5842	25	40	and	and	CCONJ
fnp-5842	25	41	contribute	contribute	VERB
fnp-5842	25	42	to	to	ADP
fnp-5842	25	43	neuroinflammation	neuroinflammation	NOUN
fnp-5842	25	44	in	in	ADP
fnp-5842	25	45	vivo	vivo	ADJ
fnp-5842	25	46	p22	p22	NOUN
fnp-5842	25	47	alterations	alteration	NOUN
fnp-5842	25	48	of	of	ADP
fnp-5842	25	49	er	er	INTJ
fnp-5842	25	50	-	-	PUNCT
fnp-5842	25	51	co	co	ADJ
fnp-5842	25	52	-	-	ADJ
fnp-5842	25	53	chaperone	chaperone	ADJ
fnp-5842	25	54	sil1	sil1	NOUN
fnp-5842	25	55	in	in	ADP
fnp-5842	25	56	amyotrophic	amyotrophic	ADJ
fnp-5842	25	57	lateral	lateral	ADJ
fnp-5842	25	58	sclerosis	sclerosis	NOUN
fnp-5842	25	59	(	(	PUNCT
fnp-5842	25	60	als	als	NOUN
fnp-5842	25	61	)	)	PUNCT
fnp-5842	25	62	p23	p23	NOUN
fnp-5842	25	63	characterizing	characterize	VERB
fnp-5842	25	64	granular	granular	ADJ
fnp-5842	25	65	tau	tau	NOUN
fnp-5842	25	66	aggregates	aggregate	NOUN
fnp-5842	25	67	in	in	ADP
fnp-5842	25	68	astrocytes	astrocyte	NOUN
fnp-5842	25	69	in	in	ADP
fnp-5842	25	70	multiple	multiple	ADJ
fnp-5842	25	71	system	system	NOUN
fnp-5842	25	72	atrophy	atrophy	NOUN
fnp-5842	25	73	v.	v.	ADP
fnp-5842	25	74	methods	method	NOUN
fnp-5842	25	75	and	and	CCONJ
fnp-5842	25	76	free	free	ADJ
fnp-5842	25	77	topics	topic	NOUN
fnp-5842	26	1	p24	p24	VERB
fnp-5842	26	2	ultra	ultra	ADJ
fnp-5842	26	3	-	-	ADJ
fnp-5842	26	4	rapid	rapid	ADJ
fnp-5842	26	5	bacterial	bacterial	ADJ
fnp-5842	26	6	detection	detection	NOUN
fnp-5842	26	7	from	from	ADP
fnp-5842	26	8	neuropathology	neuropathology	NOUN
fnp-5842	26	9	specimens	specimen	NOUN
fnp-5842	26	10	using	use	VERB
fnp-5842	26	11	next	next	ADJ
fnp-5842	26	12	-	-	PUNCT
fnp-5842	26	13	generation	generation	NOUN
fnp-5842	26	14	pcr	pcr	NOUN
fnp-5842	26	15	and	and	CCONJ
fnp-5842	26	16	nanopore	nanopore	ADV
fnp-5842	26	17	sequencing	sequence	VERB
fnp-5842	26	18	p25	p25	NOUN
fnp-5842	26	19	ccnv	ccnv	NOUN
fnp-5842	26	20	:	:	PUNCT
fnp-5842	26	21	r	r	NOUN
fnp-5842	26	22	package	package	NOUN
fnp-5842	26	23	for	for	ADP
fnp-5842	26	24	enhanced	enhanced	ADJ
fnp-5842	26	25	cumulative	cumulative	ADJ
fnp-5842	26	26	copy	copy	NOUN
fnp-5842	26	27	number	number	NOUN
fnp-5842	26	28	variation	variation	NOUN
fnp-5842	26	29	analysis	analysis	NOUN
fnp-5842	26	30	p26	p26	NOUN
fnp-5842	26	31	rapid	rapid	ADJ
fnp-5842	26	32	slice	slice	NOUN
fnp-5842	26	33	-	-	PUNCT
fnp-5842	26	34	free	free	ADJ
fnp-5842	26	35	intraoperative	intraoperative	ADJ
fnp-5842	26	36	histology	histology	NOUN
fnp-5842	26	37	in	in	ADP
fnp-5842	26	38	neurooncology	neurooncology	NOUN
fnp-5842	26	39	using	use	VERB
fnp-5842	26	40	multiphoton	multiphoton	NOUN
fnp-5842	26	41	microscopy	microscopy	NOUN
fnp-5842	26	42	–	–	PUNCT
fnp-5842	26	43	first	first	ADJ
fnp-5842	26	44	study	study	NOUN
fnp-5842	26	45	results	result	VERB
fnp-5842	26	46	p27	p27	NOUN
fnp-5842	26	47	predicting	predict	VERB
fnp-5842	26	48	epigenetic	epigenetic	ADJ
fnp-5842	26	49	ependymoma	ependymoma	NOUN
fnp-5842	26	50	types	type	NOUN
fnp-5842	26	51	from	from	ADP
fnp-5842	26	52	histological	histological	ADJ
fnp-5842	26	53	whole	whole	ADJ
fnp-5842	26	54	-	-	PUNCT
fnp-5842	26	55	slide	slide	NOUN
fnp-5842	26	56	images	image	NOUN
fnp-5842	26	57	using	use	VERB
fnp-5842	26	58	neural	neural	ADJ
fnp-5842	26	59	networks	network	NOUN
fnp-5842	26	60	p28	p28	NOUN
fnp-5842	26	61	established	establish	VERB
fnp-5842	26	62	in	in	ADP
fnp-5842	26	63	1902	1902	NUM
fnp-5842	26	64	:	:	PUNCT
fnp-5842	26	65	a	a	DET
fnp-5842	26	66	brief	brief	ADJ
fnp-5842	26	67	history	history	NOUN
fnp-5842	26	68	of	of	ADP
fnp-5842	26	69	the	the	DET
fnp-5842	26	70	institute	institute	PROPN
fnp-5842	26	71	of	of	ADP
fnp-5842	26	72	neurology	neurology	NOUN
fnp-5842	26	73	(	(	PUNCT
fnp-5842	26	74	edinger	edinger	PROPN
fnp-5842	26	75	institute	institute	PROPN
fnp-5842	26	76	)	)	PUNCT
fnp-5842	26	77	in	in	ADP
fnp-5842	26	78	frankfurt	frankfurt	PROPN
fnp-5842	26	79	,	,	PUNCT
fnp-5842	26	80	germany	germany	PROPN
fnp-5842	26	81	p29	p29	PROPN
fnp-5842	26	82	paving	pave	VERB
fnp-5842	26	83	the	the	DET
fnp-5842	26	84	path	path	NOUN
fnp-5842	26	85	:	:	PUNCT
fnp-5842	26	86	the	the	DET
fnp-5842	26	87	powerful	powerful	ADJ
fnp-5842	26	88	effect	effect	NOUN
fnp-5842	26	89	of	of	ADP
fnp-5842	26	90	substrate	substrate	NOUN
fnp-5842	26	91	topography	topography	NOUN
fnp-5842	26	92	on	on	ADP
fnp-5842	26	93	axon	axon	NOUN
fnp-5842	26	94	-	-	PUNCT
fnp-5842	26	95	repulsive	repulsive	ADJ
fnp-5842	26	96	schwann	schwann	PROPN
fnp-5842	26	97	cell	cell	NOUN
fnp-5842	26	98	-	-	PUNCT
fnp-5842	26	99	astrocyte	astrocyte	NOUN
fnp-5842	26	100	barrier	barrier	NOUN
fnp-5842	26	101	formation	formation	NOUN
fnp-5842	26	102	for	for	ADP
fnp-5842	26	103	spinal	spinal	ADJ
fnp-5842	26	104	cord	cord	NOUN
fnp-5842	26	105	injury	injury	NOUN
fnp-5842	26	106	repair	repair	NOUN
fnp-5842	26	107	p30	p30	NOUN
fnp-5842	26	108	using	use	VERB
fnp-5842	26	109	eye	eye	NOUN
fnp-5842	26	110	-	-	PUNCT
fnp-5842	26	111	tracking	tracking	NOUN
fnp-5842	26	112	to	to	PART
fnp-5842	26	113	find	find	VERB
fnp-5842	26	114	differences	difference	NOUN
fnp-5842	26	115	in	in	ADP
fnp-5842	26	116	the	the	DET
fnp-5842	26	117	analysis	analysis	NOUN
fnp-5842	26	118	of	of	ADP
fnp-5842	26	119	whole	whole	ADJ
fnp-5842	26	120	-	-	PUNCT
fnp-5842	26	121	slide	slide	NOUN
fnp-5842	26	122	images	image	NOUN
fnp-5842	26	123	between	between	ADP
fnp-5842	26	124	physicians	physician	NOUN
fnp-5842	26	125	and	and	CCONJ
fnp-5842	26	126	machine	machine	NOUN
fnp-5842	26	127	learning	learning	NOUN
fnp-5842	26	128	models	model	NOUN
fnp-5842	26	129	–	–	PUNCT
fnp-5842	26	130	a	a	DET
fnp-5842	26	131	study	study	NOUN
fnp-5842	26	132	design	design	NOUN
fnp-5842	26	133	p31	p31	NOUN
fnp-5842	26	134	why	why	SCONJ
fnp-5842	26	135	we	we	PRON
fnp-5842	26	136	do	do	AUX
fnp-5842	26	137	n’t	not	PART
fnp-5842	26	138	save	save	VERB
fnp-5842	26	139	whole	whole	ADJ
fnp-5842	26	140	-	-	PUNCT
fnp-5842	26	141	slide	slide	NOUN
fnp-5842	26	142	images	image	NOUN
fnp-5842	26	143	as	as	ADP
fnp-5842	26	144	lego	lego	NOUN
fnp-5842	26	145	mosaics	mosaic	NOUN
fnp-5842	26	146	–	–	PUNCT
fnp-5842	26	147	putting	put	VERB
fnp-5842	26	148	the	the	DET
fnp-5842	26	149	scale	scale	NOUN
fnp-5842	26	150	of	of	ADP
fnp-5842	26	151	whole	whole	ADJ
fnp-5842	26	152	-	-	PUNCT
fnp-5842	26	153	slide	slide	NOUN
fnp-5842	26	154	images	image	NOUN
fnp-5842	26	155	into	into	ADP
fnp-5842	26	156	perspective	perspective	ADJ
fnp-5842	26	157	i.	i.	PROPN
fnp-5842	26	158	neurooncology	neurooncology	PROPN
fnp-5842	26	159	p01	p01	PROPN
fnp-5842	26	160	free	free	ADJ
fnp-5842	26	161	neuropathol	neuropathol	NOUN
fnp-5842	26	162	5:19:5	5:19:5	NUM
fnp-5842	26	163	identification	identification	NOUN
fnp-5842	26	164	and	and	CCONJ
fnp-5842	26	165	description	description	NOUN
fnp-5842	26	166	of	of	ADP
fnp-5842	26	167	a	a	DET
fnp-5842	26	168	novel	novel	ADJ
fnp-5842	26	169	type	type	NOUN
fnp-5842	26	170	of	of	ADP
fnp-5842	26	171	medulloblastoma	medulloblastoma	NOUN
fnp-5842	26	172	alicia	alicia	PROPN
fnp-5842	26	173	eckhardt1,2	eckhardt1,2	PROPN
fnp-5842	26	174	,	,	PUNCT
fnp-5842	26	175	*	*	PROPN
fnp-5842	26	176	,	,	PUNCT
fnp-5842	26	177	chris	chris	PROPN
fnp-5842	26	178	meulenbroeks3	meulenbroeks3	PROPN
fnp-5842	26	179	,	,	PUNCT
fnp-5842	26	180	*	*	PROPN
fnp-5842	26	181	,	,	PUNCT
fnp-5842	26	182	neal	neal	PROPN
fnp-5842	26	183	geisemeyer4	geisemeyer4	PROPN
fnp-5842	26	184	,	,	PUNCT
fnp-5842	26	185	*	*	PROPN
fnp-5842	26	186	,	,	PUNCT
fnp-5842	26	187	michael	michael	PROPN
fnp-5842	26	188	bockmayr1,2	bockmayr1,2	PROPN
fnp-5842	26	189	,	,	PUNCT
fnp-5842	26	190	helena	helena	PROPN
fnp-5842	26	191	bode1,2	bode1,2	PROPN
fnp-5842	26	192	,	,	PUNCT
fnp-5842	26	193	karoline	karoline	PROPN
fnp-5842	26	194	hack1,2	hack1,2	PROPN
fnp-5842	26	195	,	,	PUNCT
fnp-5842	26	196	marthe	marthe	ADJ
fnp-5842	26	197	sönksen2	sönksen2	PROPN
fnp-5842	26	198	,	,	PUNCT
fnp-5842	26	199	denise	denise	PROPN
fnp-5842	26	200	obrecht	obrecht	PROPN
fnp-5842	26	201	-	-	PUNCT
fnp-5842	26	202	sturm2	sturm2	NOUN
fnp-5842	26	203	,	,	PUNCT
fnp-5842	26	204	christian	christian	PROPN
fnp-5842	26	205	thomas5	thomas5	PROPN
fnp-5842	26	206	,	,	PUNCT
fnp-5842	26	207	melanie	melanie	PROPN
fnp-5842	26	208	schoof1,2	schoof1,2	PROPN
fnp-5842	26	209	,	,	PUNCT
fnp-5842	26	210	arend	arend	VERB
fnp-5842	26	211	koch6	koch6	PROPN
fnp-5842	26	212	,	,	PUNCT
fnp-5842	26	213	sage	sage	NOUN
fnp-5842	26	214	green7,8	green7,8	PROPN
fnp-5842	26	215	,	,	PUNCT
fnp-5842	26	216	sidharth	sidharth	NOUN
fnp-5842	26	217	mahapatra9	mahapatra9	PROPN
fnp-5842	26	218	,	,	PUNCT
fnp-5842	26	219	dave	dave	PROPN
fnp-5842	26	220	doss10	doss10	PROPN
fnp-5842	26	221	,	,	PUNCT
fnp-5842	26	222	ekin	ekin	NOUN
fnp-5842	26	223	guney11	guney11	NOUN
fnp-5842	26	224	,	,	PUNCT
fnp-5842	26	225	arie	arie	NOUN
fnp-5842	26	226	perry11	perry11	NOUN
fnp-5842	26	227	,	,	PUNCT
fnp-5842	26	228	kenneth	kenneth	PROPN
fnp-5842	26	229	aldape12	aldape12	PROPN
fnp-5842	26	230	,	,	PUNCT
fnp-5842	26	231	anna	anna	PROPN
fnp-5842	26	232	darabi13	darabi13	PROPN
fnp-5842	26	233	,	,	PUNCT
fnp-5842	26	234	stephan	stephan	PROPN
fnp-5842	26	235	frank14	frank14	PROPN
fnp-5842	26	236	,	,	PUNCT
fnp-5842	26	237	peter	peter	PROPN
fnp-5842	26	238	kuzman15	kuzman15	PROPN
fnp-5842	26	239	,	,	PUNCT
fnp-5842	26	240	miriam	miriam	PROPN
fnp-5842	26	241	ratliff16,17	ratliff16,17	PROPN
fnp-5842	26	242	,	,	PUNCT
fnp-5842	26	243	abigail	abigail	PROPN
fnp-5842	26	244	suwala18,19	suwala18,19	PROPN
fnp-5842	26	245	,	,	PUNCT
fnp-5842	26	246	andrey	andrey	PROPN
fnp-5842	26	247	korshunov18,19	korshunov18,19	PROPN
fnp-5842	26	248	,	,	PUNCT
fnp-5842	26	249	olivier	olivier	PROPN
fnp-5842	26	250	ayrault20	ayrault20	PROPN
fnp-5842	26	251	,	,	PUNCT
fnp-5842	26	252	christine	christine	PROPN
fnp-5842	26	253	haberler21	haberler21	PROPN
fnp-5842	26	254	,	,	PUNCT
fnp-5842	26	255	ales	ales	PROPN
fnp-5842	26	256	vicha22	vicha22	PROPN
fnp-5842	26	257	,	,	PUNCT
fnp-5842	26	258	markus	markus	NOUN
fnp-5842	26	259	glatzel23	glatzel23	NOUN
fnp-5842	26	260	,	,	PUNCT
fnp-5842	26	261	martin	martin	PROPN
fnp-5842	26	262	mynarek2	mynarek2	PROPN
fnp-5842	26	263	,	,	PUNCT
fnp-5842	26	264	stefan	stefan	PROPN
fnp-5842	26	265	rutkowski2	rutkowski2	PROPN
fnp-5842	26	266	,	,	PUNCT
fnp-5842	26	267	martin	martin	PROPN
fnp-5842	26	268	hasselblatt5	hasselblatt5	PROPN
fnp-5842	26	269	,	,	PUNCT
fnp-5842	26	270	michael	michael	PROPN
fnp-5842	26	271	d	d	PROPN
fnp-5842	26	272	taylor24	taylor24	PROPN
fnp-5842	26	273	,	,	PUNCT
fnp-5842	26	274	david	david	PROPN
fnp-5842	26	275	jones25,26	jones25,26	PROPN
fnp-5842	26	276	,	,	PUNCT
fnp-5842	26	277	marcel	marcel	PROPN
fnp-5842	26	278	kool3,4	kool3,4	PROPN
fnp-5842	26	279	,	,	PUNCT
fnp-5842	26	280	*	*	PROPN
fnp-5842	26	281	,	,	PUNCT
fnp-5842	26	282	ulrich	ulrich	PROPN
fnp-5842	26	283	schüller1,2,23	schüller1,2,23	PROPN
fnp-5842	26	284	,	,	PUNCT
fnp-5842	26	285	*	*	PROPN
fnp-5842	26	286	1	1	NUM
fnp-5842	26	287	research	research	NOUN
fnp-5842	26	288	institute	institute	NOUN
fnp-5842	26	289	children	child	NOUN
fnp-5842	26	290	’s	’s	PART
fnp-5842	26	291	cancer	cancer	NOUN
fnp-5842	26	292	center	center	PROPN
fnp-5842	26	293	hamburg	hamburg	PROPN
fnp-5842	26	294	,	,	PUNCT
fnp-5842	26	295	hamburg	hamburg	PROPN
fnp-5842	26	296	,	,	PUNCT
fnp-5842	26	297	germany	germany	PROPN
fnp-5842	26	298	2	2	NUM
fnp-5842	26	299	pediatric	pediatric	ADJ
fnp-5842	26	300	hematology	hematology	NOUN
fnp-5842	26	301	and	and	CCONJ
fnp-5842	26	302	oncology	oncology	NOUN
fnp-5842	26	303	,	,	PUNCT
fnp-5842	26	304	university	university	NOUN
fnp-5842	26	305	medical	medical	ADJ
fnp-5842	26	306	center	center	PROPN
fnp-5842	26	307	hamburg	hamburg	PROPN
fnp-5842	26	308	-	-	PUNCT
fnp-5842	26	309	eppendorf	eppendorf	PROPN
fnp-5842	26	310	,	,	PUNCT
fnp-5842	26	311	hamburg	hamburg	PROPN
fnp-5842	26	312	,	,	PUNCT
fnp-5842	26	313	germany	germany	PROPN
fnp-5842	26	314	3	3	NUM
fnp-5842	26	315	princess	princess	NOUN
fnp-5842	26	316	máxima	máxima	PROPN
fnp-5842	26	317	center	center	NOUN
fnp-5842	26	318	for	for	ADP
fnp-5842	26	319	pediatric	pediatric	ADJ
fnp-5842	26	320	oncology	oncology	NOUN
fnp-5842	26	321	,	,	PUNCT
fnp-5842	26	322	utrecht	utrecht	PROPN
fnp-5842	26	323	,	,	PUNCT
fnp-5842	26	324	netherlands	netherlands	PROPN
fnp-5842	26	325	4	4	NUM
fnp-5842	26	326	hopp	hopp	PROPN
fnp-5842	26	327	children	children	PROPN
fnp-5842	26	328	’s	’s	PART
fnp-5842	26	329	cancer	cancer	NOUN
fnp-5842	26	330	center	center	PROPN
fnp-5842	26	331	heidelberg	heidelberg	PROPN
fnp-5842	26	332	(	(	PUNCT
fnp-5842	26	333	kitz	kitz	PROPN
fnp-5842	26	334	)	)	PUNCT
fnp-5842	26	335	/	/	SYM
fnp-5842	26	336	german	german	ADJ
fnp-5842	26	337	cancer	cancer	NOUN
fnp-5842	26	338	research	research	NOUN
fnp-5842	26	339	center	center	NOUN
fnp-5842	26	340	(	(	PUNCT
fnp-5842	26	341	dkfz	dkfz	PROPN
fnp-5842	26	342	)	)	PUNCT
fnp-5842	26	343	,	,	PUNCT
fnp-5842	26	344	heidelberg	heidelberg	PROPN
fnp-5842	26	345	,	,	PUNCT
fnp-5842	26	346	germany	germany	PROPN
fnp-5842	26	347	5	5	NUM
fnp-5842	26	348	institute	institute	PROPN
fnp-5842	26	349	of	of	ADP
fnp-5842	26	350	neuropathology	neuropathology	NOUN
fnp-5842	26	351	,	,	PUNCT
fnp-5842	26	352	university	university	NOUN
fnp-5842	26	353	hospital	hospital	NOUN
fnp-5842	26	354	münster	münster	NOUN
fnp-5842	26	355	,	,	PUNCT
fnp-5842	26	356	münster	münster	PROPN
fnp-5842	26	357	,	,	PUNCT
fnp-5842	26	358	germany	germany	PROPN
fnp-5842	26	359	6	6	NUM
fnp-5842	26	360	department	department	NOUN
fnp-5842	26	361	of	of	ADP
fnp-5842	26	362	neuropathology	neuropathology	NOUN
fnp-5842	26	363	,	,	PUNCT
fnp-5842	26	364	charité	charité	PROPN
fnp-5842	26	365	universitätsmedizin	universitätsmedizin	PROPN
fnp-5842	26	366	berlin	berlin	PROPN
fnp-5842	26	367	,	,	PUNCT
fnp-5842	26	368	corporate	corporate	ADJ
fnp-5842	26	369	member	member	NOUN
fnp-5842	26	370	of	of	ADP
fnp-5842	26	371	freie	freie	PROPN
fnp-5842	26	372	universität	universität	PROPN
fnp-5842	26	373	berlin	berlin	PROPN
fnp-5842	26	374	,	,	PUNCT
fnp-5842	26	375	and	and	CCONJ
fnp-5842	26	376	berlin	berlin	PROPN
fnp-5842	26	377	institute	institute	PROPN
fnp-5842	26	378	of	of	ADP
fnp-5842	26	379	health	health	PROPN
fnp-5842	26	380	,	,	PUNCT
fnp-5842	26	381	charité	charité	PROPN
fnp-5842	26	382	university	university	NOUN
fnp-5842	26	383	medicine	medicine	NOUN
fnp-5842	26	384	,	,	PUNCT
fnp-5842	26	385	berlin	berlin	PROPN
fnp-5842	26	386	,	,	PUNCT
fnp-5842	26	387	germany	germany	PROPN
fnp-5842	26	388	7	7	NUM
fnp-5842	26	389	dell	dell	PROPN
fnp-5842	26	390	children	child	NOUN
fnp-5842	26	391	's	's	PART
fnp-5842	26	392	medical	medical	ADJ
fnp-5842	26	393	center	center	NOUN
fnp-5842	26	394	,	,	PUNCT
fnp-5842	26	395	austin	austin	PROPN
fnp-5842	26	396	,	,	PUNCT
fnp-5842	26	397	tx	tx	PROPN
fnp-5842	26	398	,	,	PUNCT
fnp-5842	26	399	usa	usa	PROPN
fnp-5842	26	400	8	8	PROPN
fnp-5842	26	401	nemours	nemour	VERB
fnp-5842	26	402	children	child	NOUN
fnp-5842	26	403	's	's	PART
fnp-5842	26	404	health	health	NOUN
fnp-5842	26	405	,	,	PUNCT
fnp-5842	26	406	wilmington	wilmington	PROPN
fnp-5842	26	407	,	,	PUNCT
fnp-5842	26	408	de	de	PROPN
fnp-5842	26	409	,	,	PUNCT
fnp-5842	26	410	usa	usa	PROPN
fnp-5842	26	411	9	9	NUM
fnp-5842	26	412	university	university	PROPN
fnp-5842	26	413	of	of	ADP
fnp-5842	26	414	nebraska	nebraska	PROPN
fnp-5842	26	415	medical	medical	ADJ
fnp-5842	26	416	center	center	PROPN
fnp-5842	26	417	,	,	PUNCT
fnp-5842	26	418	omaha	omaha	PROPN
fnp-5842	26	419	,	,	PUNCT
fnp-5842	26	420	ne	ne	PROPN
fnp-5842	26	421	,	,	PUNCT
fnp-5842	26	422	usa	usa	PROPN
fnp-5842	26	423	10	10	NUM
fnp-5842	26	424	creighton	creighton	PROPN
fnp-5842	26	425	university	university	PROPN
fnp-5842	26	426	school	school	NOUN
fnp-5842	26	427	of	of	ADP
fnp-5842	26	428	medicine	medicine	NOUN
fnp-5842	26	429	,	,	PUNCT
fnp-5842	26	430	omaha	omaha	PROPN
fnp-5842	26	431	,	,	PUNCT
fnp-5842	26	432	ne	ne	PROPN
fnp-5842	26	433	,	,	PUNCT
fnp-5842	26	434	usa	usa	PROPN
fnp-5842	26	435	11	11	NUM
fnp-5842	26	436	department	department	NOUN
fnp-5842	26	437	of	of	ADP
fnp-5842	26	438	pathology	pathology	PROPN
fnp-5842	26	439	,	,	PUNCT
fnp-5842	26	440	university	university	PROPN
fnp-5842	26	441	of	of	ADP
fnp-5842	26	442	california	california	PROPN
fnp-5842	26	443	,	,	PUNCT
fnp-5842	26	444	san	san	PROPN
fnp-5842	26	445	francisco	francisco	PROPN
fnp-5842	26	446	,	,	PUNCT
fnp-5842	26	447	san	san	PROPN
fnp-5842	26	448	francisco	francisco	PROPN
fnp-5842	26	449	,	,	PUNCT
fnp-5842	26	450	ca	ca	PROPN
fnp-5842	26	451	,	,	PUNCT
fnp-5842	26	452	usa	usa	PROPN
fnp-5842	26	453	12	12	NUM
fnp-5842	26	454	laboratory	laboratory	NOUN
fnp-5842	26	455	of	of	ADP
fnp-5842	26	456	pathology	pathology	NOUN
fnp-5842	26	457	,	,	PUNCT
fnp-5842	26	458	center	center	NOUN
fnp-5842	26	459	for	for	ADP
fnp-5842	26	460	cancer	cancer	NOUN
fnp-5842	26	461	research	research	NOUN
fnp-5842	26	462	,	,	PUNCT
fnp-5842	26	463	national	national	PROPN
fnp-5842	26	464	cancer	cancer	PROPN
fnp-5842	26	465	institute	institute	PROPN
fnp-5842	26	466	,	,	PUNCT
fnp-5842	26	467	bethesda	bethesda	PROPN
fnp-5842	26	468	,	,	PUNCT
fnp-5842	26	469	md	md	PROPN
fnp-5842	26	470	,	,	PUNCT
fnp-5842	26	471	usa	usa	PROPN
fnp-5842	26	472	13	13	NUM
fnp-5842	26	473	glioma	glioma	NOUN
fnp-5842	26	474	immunotherapy	immunotherapy	NOUN
fnp-5842	26	475	group	group	NOUN
fnp-5842	26	476	,	,	PUNCT
fnp-5842	26	477	neurosurgery	neurosurgery	NOUN
fnp-5842	26	478	,	,	PUNCT
fnp-5842	26	479	department	department	NOUN
fnp-5842	26	480	of	of	ADP
fnp-5842	26	481	clinical	clinical	ADJ
fnp-5842	26	482	sciences	science	NOUN
fnp-5842	26	483	,	,	PUNCT
fnp-5842	26	484	lund	lund	PROPN
fnp-5842	26	485	university	university	PROPN
fnp-5842	26	486	,	,	PUNCT
fnp-5842	26	487	lund	lund	PROPN
fnp-5842	26	488	,	,	PUNCT
fnp-5842	26	489	sweden	sweden	PROPN
fnp-5842	26	490	14	14	NUM
fnp-5842	26	491	division	division	NOUN
fnp-5842	26	492	of	of	ADP
fnp-5842	26	493	neuropathology	neuropathology	NOUN
fnp-5842	26	494	,	,	PUNCT
fnp-5842	26	495	institute	institute	NOUN
fnp-5842	26	496	of	of	ADP
fnp-5842	26	497	medical	medical	ADJ
fnp-5842	26	498	genetics	genetic	NOUN
fnp-5842	26	499	and	and	CCONJ
fnp-5842	26	500	pathology	pathology	NOUN
fnp-5842	26	501	,	,	PUNCT
fnp-5842	26	502	university	university	NOUN
fnp-5842	26	503	hospital	hospital	NOUN
fnp-5842	26	504	basel	basel	PROPN
fnp-5842	26	505	,	,	PUNCT
fnp-5842	26	506	university	university	PROPN
fnp-5842	26	507	of	of	ADP
fnp-5842	26	508	basel	basel	PROPN
fnp-5842	26	509	,	,	PUNCT
fnp-5842	26	510	basel	basel	PROPN
fnp-5842	26	511	,	,	PUNCT
fnp-5842	26	512	switzerland	switzerland	PROPN
fnp-5842	26	513	15	15	NUM
fnp-5842	26	514	institute	institute	PROPN
fnp-5842	26	515	of	of	ADP
fnp-5842	26	516	neuropathology	neuropathology	NOUN
fnp-5842	26	517	,	,	PUNCT
fnp-5842	26	518	university	university	NOUN
fnp-5842	26	519	hospital	hospital	NOUN
fnp-5842	26	520	leipzig	leipzig	PROPN
fnp-5842	26	521	,	,	PUNCT
fnp-5842	26	522	leipzig	leipzig	PROPN
fnp-5842	26	523	,	,	PUNCT
fnp-5842	26	524	germany	germany	PROPN
fnp-5842	26	525	16	16	NUM
fnp-5842	26	526	clinical	clinical	ADJ
fnp-5842	26	527	cooperation	cooperation	NOUN
fnp-5842	26	528	unit	unit	NOUN
fnp-5842	26	529	neurooncology	neurooncology	NOUN
fnp-5842	26	530	,	,	PUNCT
fnp-5842	26	531	german	german	ADJ
fnp-5842	26	532	cancer	cancer	NOUN
fnp-5842	26	533	consortium	consortium	NOUN
fnp-5842	26	534	(	(	PUNCT
fnp-5842	26	535	dktk	dktk	NOUN
fnp-5842	26	536	)	)	PUNCT
fnp-5842	26	537	,	,	PUNCT
fnp-5842	26	538	german	german	ADJ
fnp-5842	26	539	cancer	cancer	NOUN
fnp-5842	26	540	research	research	NOUN
fnp-5842	26	541	center	center	NOUN
fnp-5842	26	542	(	(	PUNCT
fnp-5842	26	543	dkfz	dkfz	PROPN
fnp-5842	26	544	)	)	PUNCT
fnp-5842	26	545	,	,	PUNCT
fnp-5842	26	546	heidelberg	heidelberg	PROPN
fnp-5842	26	547	,	,	PUNCT
fnp-5842	26	548	germany	germany	PROPN
fnp-5842	26	549	17	17	NUM
fnp-5842	26	550	neurosurgery	neurosurgery	NOUN
fnp-5842	26	551	clinic	clinic	NOUN
fnp-5842	26	552	,	,	PUNCT
fnp-5842	26	553	university	university	NOUN
fnp-5842	26	554	hospital	hospital	NOUN
fnp-5842	26	555	mannheim	mannheim	PROPN
fnp-5842	26	556	,	,	PUNCT
fnp-5842	26	557	mannheim	mannheim	PROPN
fnp-5842	26	558	,	,	PUNCT
fnp-5842	26	559	germany	germany	PROPN
fnp-5842	26	560	18	18	NUM
fnp-5842	26	561	department	department	PROPN
fnp-5842	26	562	of	of	ADP
fnp-5842	26	563	neuropathology	neuropathology	NOUN
fnp-5842	26	564	,	,	PUNCT
fnp-5842	26	565	institute	institute	PROPN
fnp-5842	26	566	of	of	ADP
fnp-5842	26	567	pathology	pathology	PROPN
fnp-5842	26	568	,	,	PUNCT
fnp-5842	26	569	university	university	PROPN
fnp-5842	26	570	of	of	ADP
fnp-5842	26	571	heidelberg	heidelberg	PROPN
fnp-5842	26	572	,	,	PUNCT
fnp-5842	26	573	heidelberg	heidelberg	PROPN
fnp-5842	26	574	,	,	PUNCT
fnp-5842	26	575	germany	germany	PROPN
fnp-5842	26	576	19	19	NUM
fnp-5842	26	577	clinical	clinical	ADJ
fnp-5842	26	578	cooperation	cooperation	NOUN
fnp-5842	26	579	unit	unit	NOUN
fnp-5842	26	580	neuropathology	neuropathology	NOUN
fnp-5842	26	581	,	,	PUNCT
fnp-5842	26	582	german	german	ADJ
fnp-5842	26	583	cancer	cancer	NOUN
fnp-5842	26	584	research	research	NOUN
fnp-5842	26	585	center	center	NOUN
fnp-5842	26	586	(	(	PUNCT
fnp-5842	26	587	dkfz	dkfz	PROPN
fnp-5842	26	588	)	)	PUNCT
fnp-5842	26	589	,	,	PUNCT
fnp-5842	26	590	german	german	ADJ
fnp-5842	26	591	consortium	consortium	NOUN
fnp-5842	26	592	for	for	ADP
fnp-5842	26	593	translational	translational	ADJ
fnp-5842	26	594	cancer	cancer	NOUN
fnp-5842	26	595	research	research	NOUN
fnp-5842	26	596	(	(	PUNCT
fnp-5842	26	597	dktk	dktk	NOUN
fnp-5842	26	598	)	)	PUNCT
fnp-5842	26	599	,	,	PUNCT
fnp-5842	26	600	heidelberg	heidelberg	PROPN
fnp-5842	26	601	,	,	PUNCT
fnp-5842	26	602	germany	germany	PROPN
fnp-5842	26	603	20	20	PROPN
fnp-5842	26	604	institut	institut	PROPN
fnp-5842	26	605	curie	curie	PROPN
fnp-5842	26	606	,	,	PUNCT
fnp-5842	26	607	cnrs	cnrs	NOUN
fnp-5842	26	608	umr	umr	PROPN
fnp-5842	26	609	,	,	PUNCT
fnp-5842	26	610	inserm	inserm	NOUN
fnp-5842	26	611	,	,	PUNCT
fnp-5842	26	612	psl	psl	PROPN
fnp-5842	26	613	research	research	PROPN
fnp-5842	26	614	university	university	PROPN
fnp-5842	26	615	,	,	PUNCT
fnp-5842	26	616	orsay	orsay	PROPN
fnp-5842	26	617	,	,	PUNCT
fnp-5842	26	618	france	france	PROPN
fnp-5842	26	619	;	;	PUNCT
fnp-5842	26	620	cnrs	cnrs	NOUN
fnp-5842	26	621	umr	umr	ADJ
fnp-5842	26	622	3347	3347	NUM
fnp-5842	26	623	,	,	PUNCT
fnp-5842	26	624	inserm	inserm	NOUN
fnp-5842	26	625	u1021	u1021	PROPN
fnp-5842	26	626	,	,	PUNCT
fnp-5842	26	627	universite	universite	PROPN
fnp-5842	26	628	paris	paris	PROPN
fnp-5842	26	629	sud	sud	PROPN
fnp-5842	26	630	,	,	PUNCT
fnp-5842	26	631	universite	universite	PROPN
fnp-5842	26	632	paris	paris	PROPN
fnp-5842	26	633	-	-	PUNCT
fnp-5842	26	634	saclay	saclay	NOUN
fnp-5842	26	635	,	,	PUNCT
fnp-5842	26	636	orsay	orsay	PROPN
fnp-5842	26	637	,	,	PUNCT
fnp-5842	26	638	france	france	PROPN
fnp-5842	26	639	21	21	NUM
fnp-5842	26	640	institute	institute	PROPN
fnp-5842	26	641	of	of	ADP
fnp-5842	26	642	neurology	neurology	NOUN
fnp-5842	26	643	,	,	PUNCT
fnp-5842	26	644	medical	medical	ADJ
fnp-5842	26	645	university	university	PROPN
fnp-5842	26	646	of	of	ADP
fnp-5842	26	647	vienna	vienna	PROPN
fnp-5842	26	648	,	,	PUNCT
fnp-5842	26	649	vienna	vienna	PROPN
fnp-5842	26	650	,	,	PUNCT
fnp-5842	26	651	austria	austria	PROPN
fnp-5842	26	652	22	22	NUM
fnp-5842	26	653	prague	prague	PROPN
fnp-5842	26	654	brain	brain	NOUN
fnp-5842	26	655	tumor	tumor	PROPN
fnp-5842	26	656	research	research	NOUN
fnp-5842	26	657	group	group	NOUN
fnp-5842	26	658	,	,	PUNCT
fnp-5842	26	659	second	second	ADJ
fnp-5842	26	660	faculty	faculty	NOUN
fnp-5842	26	661	of	of	ADP
fnp-5842	26	662	medicine	medicine	NOUN
fnp-5842	26	663	,	,	PUNCT
fnp-5842	26	664	charles	charles	PROPN
fnp-5842	26	665	university	university	PROPN
fnp-5842	26	666	and	and	CCONJ
fnp-5842	26	667	university	university	NOUN
fnp-5842	26	668	hospital	hospital	NOUN
fnp-5842	26	669	motol	motol	NOUN
fnp-5842	26	670	,	,	PUNCT
fnp-5842	26	671	v	v	ADP
fnp-5842	26	672	uvalu	uvalu	PROPN
fnp-5842	26	673	84	84	NUM
fnp-5842	26	674	,	,	PUNCT
fnp-5842	26	675	15006	15006	NUM
fnp-5842	26	676	,	,	PUNCT
fnp-5842	26	677	prague	prague	NOUN
fnp-5842	26	678	5	5	NUM
fnp-5842	26	679	,	,	PUNCT
fnp-5842	26	680	czech	czech	PROPN
fnp-5842	26	681	republic	republic	PROPN
fnp-5842	26	682	23	23	NUM
fnp-5842	26	683	institute	institute	PROPN
fnp-5842	26	684	of	of	ADP
fnp-5842	26	685	neuropathology	neuropathology	NOUN
fnp-5842	26	686	,	,	PUNCT
fnp-5842	26	687	university	university	NOUN
fnp-5842	26	688	medical	medical	ADJ
fnp-5842	26	689	center	center	PROPN
fnp-5842	26	690	hamburg	hamburg	PROPN
fnp-5842	26	691	-	-	PUNCT
fnp-5842	26	692	eppendorf	eppendorf	PROPN
fnp-5842	26	693	,	,	PUNCT
fnp-5842	26	694	hamburg	hamburg	PROPN
fnp-5842	26	695	,	,	PUNCT
fnp-5842	26	696	germany	germany	PROPN
fnp-5842	26	697	24	24	NUM
fnp-5842	26	698	division	division	NOUN
fnp-5842	26	699	of	of	ADP
fnp-5842	26	700	neurosurgery	neurosurgery	NOUN
fnp-5842	26	701	,	,	PUNCT
fnp-5842	26	702	the	the	DET
fnp-5842	26	703	hospital	hospital	NOUN
fnp-5842	26	704	for	for	ADP
fnp-5842	26	705	sick	sick	ADJ
fnp-5842	26	706	children	child	NOUN
fnp-5842	26	707	,	,	PUNCT
fnp-5842	26	708	toronto	toronto	PROPN
fnp-5842	26	709	,	,	PUNCT
fnp-5842	26	710	ontario	ontario	PROPN
fnp-5842	26	711	,	,	PUNCT
fnp-5842	26	712	canada	canada	PROPN
fnp-5842	26	713	25	25	NUM
fnp-5842	26	714	hopp	hopp	PROPN
fnp-5842	26	715	children	child	NOUN
fnp-5842	26	716	's	's	PART
fnp-5842	26	717	cancer	cancer	NOUN
fnp-5842	26	718	center	center	NOUN
fnp-5842	26	719	heidelberg	heidelberg	PROPN
fnp-5842	26	720	(	(	PUNCT
fnp-5842	26	721	kitz	kitz	PROPN
fnp-5842	26	722	)	)	PUNCT
fnp-5842	26	723	and	and	CCONJ
fnp-5842	26	724	nct	nct	PROPN
fnp-5842	26	725	heidelberg	heidelberg	PROPN
fnp-5842	26	726	,	,	PUNCT
fnp-5842	26	727	heidelberg	heidelberg	PROPN
fnp-5842	26	728	,	,	PUNCT
fnp-5842	26	729	germany	germany	PROPN
fnp-5842	26	730	26	26	NUM
fnp-5842	26	731	division	division	NOUN
fnp-5842	26	732	of	of	ADP
fnp-5842	26	733	pediatric	pediatric	ADJ
fnp-5842	26	734	glioma	glioma	NOUN
fnp-5842	26	735	research	research	NOUN
fnp-5842	26	736	,	,	PUNCT
fnp-5842	26	737	german	german	ADJ
fnp-5842	26	738	cancer	cancer	NOUN
fnp-5842	26	739	research	research	NOUN
fnp-5842	26	740	center	center	NOUN
fnp-5842	26	741	(	(	PUNCT
fnp-5842	26	742	dkfz	dkfz	PROPN
fnp-5842	26	743	)	)	PUNCT
fnp-5842	26	744	,	,	PUNCT
fnp-5842	26	745	heidelberg	heidelberg	PROPN
fnp-5842	26	746	,	,	PUNCT
fnp-5842	26	747	germany	germany	PROPN
fnp-5842	26	748	*	*	PUNCT
fnp-5842	26	749	shared	share	VERB
fnp-5842	26	750	authorship	authorship	NOUN
fnp-5842	26	751	medulloblastoma	medulloblastoma	NOUN
fnp-5842	26	752	(	(	PUNCT
fnp-5842	26	753	mb	mb	NOUN
fnp-5842	26	754	)	)	PUNCT
fnp-5842	26	755	is	be	AUX
fnp-5842	26	756	the	the	DET
fnp-5842	26	757	most	most	ADV
fnp-5842	26	758	frequent	frequent	ADJ
fnp-5842	26	759	malignant	malignant	ADJ
fnp-5842	26	760	brain	brain	NOUN
fnp-5842	26	761	tumor	tumor	NOUN
fnp-5842	26	762	of	of	ADP
fnp-5842	26	763	childhood	childhood	NOUN
fnp-5842	26	764	and	and	CCONJ
fnp-5842	26	765	adolescence	adolescence	NOUN
fnp-5842	26	766	.	.	PUNCT
fnp-5842	27	1	based	base	VERB
fnp-5842	27	2	on	on	ADP
fnp-5842	27	3	biology	biology	NOUN
fnp-5842	27	4	,	,	PUNCT
fnp-5842	27	5	histology	histology	NOUN
fnp-5842	27	6	,	,	PUNCT
fnp-5842	27	7	and	and	CCONJ
fnp-5842	27	8	its	its	PRON
fnp-5842	27	9	clinical	clinical	ADJ
fnp-5842	27	10	course	course	NOUN
fnp-5842	27	11	,	,	PUNCT
fnp-5842	27	12	mb	mb	PROPN
fnp-5842	27	13	is	be	AUX
fnp-5842	27	14	a	a	DET
fnp-5842	27	15	heterogeneous	heterogeneous	ADJ
fnp-5842	27	16	disease	disease	NOUN
fnp-5842	27	17	with	with	ADP
fnp-5842	27	18	four	four	NUM
fnp-5842	27	19	different	different	ADJ
fnp-5842	27	20	types	type	NOUN
fnp-5842	27	21	(	(	PUNCT
fnp-5842	27	22	wnt	wnt	PROPN
fnp-5842	27	23	,	,	PUNCT
fnp-5842	27	24	shh	shh	PROPN
fnp-5842	27	25	,	,	PUNCT
fnp-5842	27	26	group	group	NOUN
fnp-5842	27	27	3	3	NUM
fnp-5842	27	28	,	,	PUNCT
fnp-5842	27	29	and	and	CCONJ
fnp-5842	27	30	group	group	NOUN
fnp-5842	27	31	4	4	NUM
fnp-5842	27	32	)	)	PUNCT
fnp-5842	27	33	,	,	PUNCT
fnp-5842	27	34	which	which	PRON
fnp-5842	27	35	are	be	AUX
fnp-5842	27	36	most	most	ADV
fnp-5842	27	37	reliably	reliably	ADV
fnp-5842	27	38	distinguishable	distinguishable	ADJ
fnp-5842	27	39	by	by	ADP
fnp-5842	27	40	their	their	PRON
fnp-5842	27	41	global	global	ADJ
fnp-5842	27	42	dna	dna	PROPN
fnp-5842	27	43	methylation	methylation	NOUN
fnp-5842	27	44	pattern	pattern	NOUN
fnp-5842	27	45	.	.	PUNCT
fnp-5842	28	1	as	as	ADP
fnp-5842	28	2	a	a	DET
fnp-5842	28	3	result	result	NOUN
fnp-5842	28	4	of	of	ADP
fnp-5842	28	5	integrating	integrate	VERB
fnp-5842	28	6	dna	dna	PROPN
fnp-5842	28	7	methylation	methylation	NOUN
fnp-5842	28	8	data	datum	NOUN
fnp-5842	28	9	of	of	ADP
fnp-5842	28	10	>	>	X
fnp-5842	28	11	 	 	SPACE
fnp-5842	28	12	2,600	2,600	NUM
fnp-5842	28	13	mbs	mb	NOUN
fnp-5842	28	14	and	and	CCONJ
fnp-5842	28	15	screening	screen	VERB
fnp-5842	28	16	of	of	ADP
fnp-5842	28	17	>	>	DET
fnp-5842	28	18	 	 	SPACE
fnp-5842	28	19	140,000	140,000	NUM
fnp-5842	28	20	data	datum	NOUN
fnp-5842	28	21	sets	set	NOUN
fnp-5842	28	22	uploaded	upload	VERB
fnp-5842	28	23	to	to	ADP
fnp-5842	28	24	the	the	DET
fnp-5842	28	25	dkfz	dkfz	ADJ
fnp-5842	28	26	brain	brain	NOUN
fnp-5842	28	27	tumor	tumor	NOUN
fnp-5842	28	28	classifier	classifier	NOUN
fnp-5842	28	29	(	(	PUNCT
fnp-5842	28	30	www.molecularneuropathology.org	www.molecularneuropathology.org	NOUN
fnp-5842	28	31	)	)	PUNCT
fnp-5842	28	32	,	,	PUNCT
fnp-5842	28	33	we	we	PRON
fnp-5842	28	34	identified	identify	VERB
fnp-5842	28	35	a	a	DET
fnp-5842	28	36	small	small	ADJ
fnp-5842	28	37	group	group	NOUN
fnp-5842	28	38	of	of	ADP
fnp-5842	28	39	mb	mb	PROPN
fnp-5842	28	40	(	(	PUNCT
fnp-5842	28	41	n	n	CCONJ
fnp-5842	28	42	 	 	SPACE
fnp-5842	28	43	=	=	NOUN
fnp-5842	28	44	 	 	SPACE
fnp-5842	28	45	49	49	NUM
fnp-5842	28	46	)	)	PUNCT
fnp-5842	28	47	that	that	PRON
fnp-5842	28	48	displayed	display	VERB
fnp-5842	28	49	a	a	DET
fnp-5842	28	50	homogeneous	homogeneous	ADJ
fnp-5842	28	51	dna	dna	PROPN
fnp-5842	28	52	methylation	methylation	NOUN
fnp-5842	28	53	pattern	pattern	NOUN
fnp-5842	28	54	,	,	PUNCT
fnp-5842	28	55	which	which	PRON
fnp-5842	28	56	was	be	AUX
fnp-5842	28	57	clearly	clearly	ADV
fnp-5842	28	58	distinct	distinct	ADJ
fnp-5842	28	59	from	from	ADP
fnp-5842	28	60	previously	previously	ADV
fnp-5842	28	61	known	know	VERB
fnp-5842	28	62	mb	mb	ADP
fnp-5842	28	63	types	type	NOUN
fnp-5842	28	64	.	.	PUNCT
fnp-5842	29	1	tumors	tumor	NOUN
fnp-5842	29	2	within	within	ADP
fnp-5842	29	3	this	this	DET
fnp-5842	29	4	group	group	NOUN
fnp-5842	29	5	have	have	AUX
fnp-5842	29	6	also	also	ADV
fnp-5842	29	7	been	be	AUX
fnp-5842	29	8	recognized	recognize	VERB
fnp-5842	29	9	as	as	ADP
fnp-5842	29	10	a	a	DET
fnp-5842	29	11	separate	separate	ADJ
fnp-5842	29	12	methylation	methylation	NOUN
fnp-5842	29	13	class	class	NOUN
fnp-5842	29	14	by	by	ADP
fnp-5842	29	15	the	the	DET
fnp-5842	29	16	latest	late	ADJ
fnp-5842	29	17	version	version	NOUN
fnp-5842	29	18	of	of	ADP
fnp-5842	29	19	the	the	DET
fnp-5842	29	20	classifier	classifier	NOUN
fnp-5842	29	21	(	(	PUNCT
fnp-5842	29	22	provisionally	provisionally	ADV
fnp-5842	29	23	named	name	VERB
fnp-5842	29	24	as	as	ADP
fnp-5842	29	25	mb_myo	mb_myo	PROPN
fnp-5842	29	26	)	)	PUNCT
fnp-5842	29	27	.	.	PUNCT
fnp-5842	30	1	transcriptomic	transcriptomic	ADJ
fnp-5842	30	2	data	datum	NOUN
fnp-5842	30	3	(	(	PUNCT
fnp-5842	30	4	n	n	CCONJ
fnp-5842	30	5	 	 	SPACE
fnp-5842	30	6	=	=	NOUN
fnp-5842	30	7	 	 	SPACE
fnp-5842	30	8	14	14	NUM
fnp-5842	30	9	)	)	PUNCT
fnp-5842	30	10	were	be	AUX
fnp-5842	30	11	similarly	similarly	ADV
fnp-5842	30	12	distinct	distinct	ADJ
fnp-5842	30	13	from	from	ADP
fnp-5842	30	14	other	other	ADJ
fnp-5842	30	15	mb	mb	PROPN
fnp-5842	30	16	types	type	NOUN
fnp-5842	30	17	.	.	PUNCT
fnp-5842	31	1	comparison	comparison	NOUN
fnp-5842	31	2	of	of	ADP
fnp-5842	31	3	these	these	DET
fnp-5842	31	4	data	datum	NOUN
fnp-5842	31	5	to	to	ADP
fnp-5842	31	6	various	various	ADJ
fnp-5842	31	7	cell	cell	NOUN
fnp-5842	31	8	types	type	NOUN
fnp-5842	31	9	of	of	ADP
fnp-5842	31	10	the	the	DET
fnp-5842	31	11	developing	develop	VERB
fnp-5842	31	12	hindbrain	hindbrain	NOUN
fnp-5842	31	13	revealed	reveal	VERB
fnp-5842	31	14	similarities	similarity	NOUN
fnp-5842	31	15	to	to	AUX
fnp-5842	31	16	precursor	precursor	NOUN
fnp-5842	31	17	cells	cell	NOUN
fnp-5842	31	18	of	of	ADP
fnp-5842	31	19	the	the	DET
fnp-5842	31	20	rhombic	rhombic	ADJ
fnp-5842	31	21	lip	lip	NOUN
fnp-5842	31	22	with	with	ADP
fnp-5842	31	23	signatures	signature	NOUN
fnp-5842	31	24	of	of	ADP
fnp-5842	31	25	wnt	wnt	NOUN
fnp-5842	31	26	signaling	signal	VERB
fnp-5842	31	27	and	and	CCONJ
fnp-5842	31	28	myogenic	myogenic	ADJ
fnp-5842	31	29	differentiation	differentiation	NOUN
fnp-5842	31	30	.	.	PUNCT
fnp-5842	32	1	in	in	ADP
fnp-5842	32	2	line	line	NOUN
fnp-5842	32	3	with	with	ADP
fnp-5842	32	4	the	the	DET
fnp-5842	32	5	latter	latter	ADJ
fnp-5842	32	6	findings	finding	NOUN
fnp-5842	32	7	,	,	PUNCT
fnp-5842	32	8	3/13	3/13	NUM
fnp-5842	32	9	analyzed	analyze	VERB
fnp-5842	32	10	cases	case	NOUN
fnp-5842	32	11	harbored	harbor	VERB
fnp-5842	32	12	hotspot	hotspot	NOUN
fnp-5842	32	13	ctnnb1	ctnnb1	NOUN
fnp-5842	32	14	mutations	mutation	NOUN
fnp-5842	32	15	and	and	CCONJ
fnp-5842	32	16	7/10	7/10	NUM
fnp-5842	32	17	cases	case	NOUN
fnp-5842	32	18	showed	show	VERB
fnp-5842	32	19	a	a	DET
fnp-5842	32	20	myogenic	myogenic	ADJ
fnp-5842	32	21	differentiation	differentiation	NOUN
fnp-5842	32	22	based	base	VERB
fnp-5842	32	23	on	on	ADP
fnp-5842	32	24	histology	histology	NOUN
fnp-5842	32	25	.	.	PUNCT
fnp-5842	33	1	myc	myc	PROPN
fnp-5842	33	2	amplifications	amplification	NOUN
fnp-5842	33	3	were	be	AUX
fnp-5842	33	4	present	present	ADJ
fnp-5842	33	5	in	in	ADP
fnp-5842	33	6	12/49	12/49	NUM
fnp-5842	33	7	(	(	PUNCT
fnp-5842	33	8	24.5	24.5	NUM
fnp-5842	33	9	 	 	SPACE
fnp-5842	33	10	%	%	NOUN
fnp-5842	33	11	)	)	PUNCT
fnp-5842	33	12	.	.	PUNCT
fnp-5842	34	1	median	median	ADJ
fnp-5842	34	2	age	age	NOUN
fnp-5842	34	3	at	at	ADP
fnp-5842	34	4	diagnosis	diagnosis	NOUN
fnp-5842	34	5	was	be	AUX
fnp-5842	34	6	16	16	NUM
fnp-5842	34	7	years	year	NOUN
fnp-5842	34	8	,	,	PUNCT
fnp-5842	34	9	and	and	CCONJ
fnp-5842	34	10	five	five	NUM
fnp-5842	34	11	-	-	PUNCT
fnp-5842	34	12	year	year	NOUN
fnp-5842	34	13	overall	overall	ADJ
fnp-5842	34	14	survival	survival	NOUN
fnp-5842	34	15	was	be	AUX
fnp-5842	34	16	~	~	PUNCT
fnp-5842	34	17	 	 	SPACE
fnp-5842	34	18	70	70	NUM
fnp-5842	34	19	 	 	SPACE
fnp-5842	34	20	%	%	NOUN
fnp-5842	34	21	.	.	PUNCT
fnp-5842	35	1	in	in	ADP
fnp-5842	35	2	summary	summary	NOUN
fnp-5842	35	3	,	,	PUNCT
fnp-5842	35	4	we	we	PRON
fnp-5842	35	5	describe	describe	VERB
fnp-5842	35	6	a	a	DET
fnp-5842	35	7	novel	novel	ADJ
fnp-5842	35	8	type	type	NOUN
fnp-5842	35	9	of	of	ADP
fnp-5842	35	10	mb	mb	ADP
fnp-5842	35	11	identified	identify	VERB
fnp-5842	35	12	by	by	ADP
fnp-5842	35	13	dna	dna	PROPN
fnp-5842	35	14	methylation	methylation	NOUN
fnp-5842	35	15	profiling	profiling	NOUN
fnp-5842	35	16	that	that	PRON
fnp-5842	35	17	likely	likely	ADV
fnp-5842	35	18	needs	need	VERB
fnp-5842	35	19	to	to	PART
fnp-5842	35	20	be	be	AUX
fnp-5842	35	21	addressed	address	VERB
fnp-5842	35	22	separately	separately	ADV
fnp-5842	35	23	during	during	ADP
fnp-5842	35	24	the	the	DET
fnp-5842	35	25	retrospective	retrospective	ADJ
fnp-5842	35	26	analyses	analysis	NOUN
fnp-5842	35	27	of	of	ADP
fnp-5842	35	28	mb	mb	ADP
fnp-5842	35	29	patient	patient	ADJ
fnp-5842	35	30	cohorts	cohort	NOUN
fnp-5842	35	31	,	,	PUNCT
fnp-5842	35	32	for	for	ADP
fnp-5842	35	33	the	the	DET
fnp-5842	35	34	design	design	NOUN
fnp-5842	35	35	of	of	ADP
fnp-5842	35	36	future	future	ADJ
fnp-5842	35	37	clinical	clinical	ADJ
fnp-5842	35	38	trials	trial	NOUN
fnp-5842	35	39	,	,	PUNCT
fnp-5842	35	40	and	and	CCONJ
fnp-5842	35	41	when	when	SCONJ
fnp-5842	35	42	evaluating	evaluate	VERB
fnp-5842	35	43	targeted	target	VERB
fnp-5842	35	44	therapies	therapy	NOUN
fnp-5842	35	45	.	.	PUNCT
fnp-5842	36	1	p02	p02	X
fnp-5842	36	2	free	free	ADJ
fnp-5842	36	3	neuropathol	neuropathol	NOUN
fnp-5842	36	4	5:19:7	5:19:7	NUM
fnp-5842	36	5	glutamatergic	glutamatergic	ADJ
fnp-5842	36	6	synaptic	synaptic	ADJ
fnp-5842	36	7	input	input	NOUN
fnp-5842	36	8	to	to	ADP
fnp-5842	36	9	brain	brain	NOUN
fnp-5842	36	10	metastases	metastasis	NOUN
fnp-5842	36	11	drives	drive	VERB
fnp-5842	36	12	metastatic	metastatic	ADJ
fnp-5842	36	13	colonization	colonization	NOUN
fnp-5842	36	14	linh	linh	NOUN
fnp-5842	36	15	-	-	PUNCT
fnp-5842	36	16	cathrin	cathrin	NOUN
fnp-5842	36	17	nguyen1	nguyen1	ADJ
fnp-5842	36	18	,	,	PUNCT
fnp-5842	36	19	matthia	matthia	PROPN
fnp-5842	36	20	karremann2,3	karremann2,3	PROPN
fnp-5842	36	21	,	,	PUNCT
fnp-5842	36	22	thomas	thomas	PROPN
fnp-5842	36	23	kuner1	kuner1	PROPN
fnp-5842	36	24	,	,	PUNCT
fnp-5842	36	25	frank	frank	PROPN
fnp-5842	36	26	winkler2,3	winkler2,3	PROPN
fnp-5842	36	27	,	,	PUNCT
fnp-5842	36	28	varun	varun	PROPN
fnp-5842	36	29	venkataramani1,2,3	venkataramani1,2,3	NOUN
fnp-5842	36	30	1	1	NUM
fnp-5842	36	31	department	department	NOUN
fnp-5842	36	32	of	of	ADP
fnp-5842	36	33	functional	functional	ADJ
fnp-5842	36	34	neuroanatomy	neuroanatomy	NOUN
fnp-5842	36	35	,	,	PUNCT
fnp-5842	36	36	institute	institute	NOUN
fnp-5842	36	37	for	for	ADP
fnp-5842	36	38	anatomy	anatomy	NOUN
fnp-5842	36	39	and	and	CCONJ
fnp-5842	36	40	cell	cell	NOUN
fnp-5842	36	41	biology	biology	NOUN
fnp-5842	36	42	,	,	PUNCT
fnp-5842	36	43	heidelberg	heidelberg	PROPN
fnp-5842	36	44	university	university	PROPN
fnp-5842	36	45	,	,	PUNCT
fnp-5842	36	46	heidelberg	heidelberg	PROPN
fnp-5842	36	47	,	,	PUNCT
fnp-5842	36	48	germany	germany	PROPN
fnp-5842	36	49	2	2	NUM
fnp-5842	36	50	clinical	clinical	ADJ
fnp-5842	36	51	cooperation	cooperation	NOUN
fnp-5842	36	52	unit	unit	NOUN
fnp-5842	36	53	neurooncology	neurooncology	NOUN
fnp-5842	36	54	,	,	PUNCT
fnp-5842	36	55	german	german	ADJ
fnp-5842	36	56	cancer	cancer	NOUN
fnp-5842	36	57	consortium	consortium	NOUN
fnp-5842	36	58	(	(	PUNCT
fnp-5842	36	59	dktk	dktk	NOUN
fnp-5842	36	60	)	)	PUNCT
fnp-5842	36	61	,	,	PUNCT
fnp-5842	36	62	german	german	ADJ
fnp-5842	36	63	cancer	cancer	NOUN
fnp-5842	36	64	research	research	NOUN
fnp-5842	36	65	center	center	NOUN
fnp-5842	36	66	(	(	PUNCT
fnp-5842	36	67	dkfz	dkfz	PROPN
fnp-5842	36	68	)	)	PUNCT
fnp-5842	36	69	,	,	PUNCT
fnp-5842	36	70	heidelberg	heidelberg	PROPN
fnp-5842	36	71	,	,	PUNCT
fnp-5842	36	72	germany	germany	PROPN
fnp-5842	36	73	3	3	NUM
fnp-5842	36	74	neurology	neurology	NOUN
fnp-5842	36	75	clinic	clinic	NOUN
fnp-5842	36	76	and	and	CCONJ
fnp-5842	36	77	national	national	ADJ
fnp-5842	36	78	center	center	NOUN
fnp-5842	36	79	for	for	ADP
fnp-5842	36	80	tumor	tumor	NOUN
fnp-5842	36	81	diseases	disease	NOUN
fnp-5842	36	82	,	,	PUNCT
fnp-5842	36	83	university	university	NOUN
fnp-5842	36	84	hospital	hospital	NOUN
fnp-5842	36	85	heidelberg	heidelberg	PROPN
fnp-5842	36	86	,	,	PUNCT
fnp-5842	36	87	heidelberg	heidelberg	PROPN
fnp-5842	36	88	,	,	PUNCT
fnp-5842	36	89	germany	germany	PROPN
fnp-5842	36	90	brain	brain	NOUN
fnp-5842	36	91	metastases	metastasis	NOUN
fnp-5842	36	92	frequently	frequently	ADV
fnp-5842	36	93	occur	occur	VERB
fnp-5842	36	94	in	in	ADP
fnp-5842	36	95	patients	patient	NOUN
fnp-5842	36	96	with	with	ADP
fnp-5842	36	97	cancer	cancer	NOUN
fnp-5842	36	98	,	,	PUNCT
fnp-5842	36	99	primarily	primarily	ADV
fnp-5842	36	100	originating	originate	VERB
fnp-5842	36	101	from	from	ADP
fnp-5842	36	102	lung	lung	NOUN
fnp-5842	36	103	carcinoma	carcinoma	NOUN
fnp-5842	36	104	,	,	PUNCT
fnp-5842	36	105	breast	breast	NOUN
fnp-5842	36	106	carcinoma	carcinoma	NOUN
fnp-5842	36	107	,	,	PUNCT
fnp-5842	36	108	and	and	CCONJ
fnp-5842	36	109	melanoma	melanoma	NOUN
fnp-5842	36	110	,	,	PUNCT
fnp-5842	36	111	resulting	result	VERB
fnp-5842	36	112	in	in	ADP
fnp-5842	36	113	high	high	ADJ
fnp-5842	36	114	morbidity	morbidity	NOUN
fnp-5842	36	115	and	and	CCONJ
fnp-5842	36	116	mortality	mortality	NOUN
fnp-5842	36	117	.	.	PUNCT
fnp-5842	37	1	the	the	DET
fnp-5842	37	2	brain	brain	NOUN
fnp-5842	37	3	microenvironment	microenvironment	NOUN
fnp-5842	37	4	significantly	significantly	ADV
fnp-5842	37	5	influences	influence	VERB
fnp-5842	37	6	the	the	DET
fnp-5842	37	7	progression	progression	NOUN
fnp-5842	37	8	of	of	ADP
fnp-5842	37	9	brain	brain	NOUN
fnp-5842	37	10	metastases	metastasis	NOUN
fnp-5842	37	11	.	.	PUNCT
fnp-5842	38	1	recent	recent	ADJ
fnp-5842	38	2	studies	study	NOUN
fnp-5842	38	3	have	have	AUX
fnp-5842	38	4	demonstrated	demonstrate	VERB
fnp-5842	38	5	that	that	SCONJ
fnp-5842	38	6	direct	direct	ADJ
fnp-5842	38	7	,	,	PUNCT
fnp-5842	38	8	glutamatergic	glutamatergic	ADJ
fnp-5842	38	9	synapses	synapsis	NOUN
fnp-5842	38	10	on	on	ADP
fnp-5842	38	11	glioma	glioma	NOUN
fnp-5842	38	12	cells	cell	NOUN
fnp-5842	38	13	drive	drive	VERB
fnp-5842	38	14	brain	brain	NOUN
fnp-5842	38	15	tumor	tumor	NOUN
fnp-5842	38	16	progression	progression	NOUN
fnp-5842	38	17	.	.	PUNCT
fnp-5842	39	1	however	however	ADV
fnp-5842	39	2	,	,	PUNCT
fnp-5842	39	3	it	it	PRON
fnp-5842	39	4	is	be	AUX
fnp-5842	39	5	unclear	unclear	ADJ
fnp-5842	39	6	if	if	SCONJ
fnp-5842	39	7	direct	direct	ADJ
fnp-5842	39	8	synaptic	synaptic	ADJ
fnp-5842	39	9	communication	communication	NOUN
fnp-5842	39	10	occurs	occur	VERB
fnp-5842	39	11	between	between	ADP
fnp-5842	39	12	neurons	neuron	NOUN
fnp-5842	39	13	and	and	CCONJ
fnp-5842	39	14	cancer	cancer	NOUN
fnp-5842	39	15	cells	cell	NOUN
fnp-5842	39	16	from	from	ADP
fnp-5842	39	17	non	non	ADJ
fnp-5842	39	18	-	-	ADJ
fnp-5842	39	19	neural	neural	ADJ
fnp-5842	39	20	tumors	tumor	NOUN
fnp-5842	39	21	,	,	PUNCT
fnp-5842	39	22	and	and	CCONJ
fnp-5842	39	23	if	if	SCONJ
fnp-5842	39	24	so	so	ADV
fnp-5842	39	25	,	,	PUNCT
fnp-5842	39	26	whether	whether	SCONJ
fnp-5842	39	27	this	this	PRON
fnp-5842	39	28	can	can	AUX
fnp-5842	39	29	promote	promote	VERB
fnp-5842	39	30	metastasis	metastasis	PRON
fnp-5842	39	31	and	and	CCONJ
fnp-5842	39	32	tumor	tumor	NOUN
fnp-5842	39	33	progression	progression	NOUN
fnp-5842	39	34	.	.	PUNCT
fnp-5842	40	1	this	this	DET
fnp-5842	40	2	study	study	NOUN
fnp-5842	40	3	aims	aim	VERB
fnp-5842	40	4	to	to	PART
fnp-5842	40	5	identify	identify	VERB
fnp-5842	40	6	and	and	CCONJ
fnp-5842	40	7	characterize	characterize	VERB
fnp-5842	40	8	direct	direct	ADJ
fnp-5842	40	9	glutamatergic	glutamatergic	ADJ
fnp-5842	40	10	synapses	synapsis	NOUN
fnp-5842	40	11	between	between	ADP
fnp-5842	40	12	neurons	neuron	NOUN
fnp-5842	40	13	and	and	CCONJ
fnp-5842	40	14	brain	brain	NOUN
fnp-5842	40	15	metastatic	metastatic	ADJ
fnp-5842	40	16	cells	cell	NOUN
fnp-5842	40	17	in	in	ADP
fnp-5842	40	18	breast	breast	NOUN
fnp-5842	40	19	cancer	cancer	NOUN
fnp-5842	40	20	and	and	CCONJ
fnp-5842	40	21	melanoma	melanoma	NOUN
fnp-5842	40	22	models	model	NOUN
fnp-5842	40	23	.	.	PUNCT
fnp-5842	41	1	we	we	PRON
fnp-5842	41	2	hypothesize	hypothesize	VERB
fnp-5842	41	3	that	that	SCONJ
fnp-5842	41	4	direct	direct	ADJ
fnp-5842	41	5	glutamatergic	glutamatergic	ADJ
fnp-5842	41	6	synapses	synapsis	NOUN
fnp-5842	41	7	are	be	AUX
fnp-5842	41	8	formed	form	VERB
fnp-5842	41	9	on	on	ADP
fnp-5842	41	10	brain	brain	NOUN
fnp-5842	41	11	metastases	metastasis	NOUN
fnp-5842	41	12	,	,	PUNCT
fnp-5842	41	13	mediating	mediate	VERB
fnp-5842	41	14	signals	signal	NOUN
fnp-5842	41	15	via	via	ADP
fnp-5842	41	16	ampa	ampa	NOUN
fnp-5842	41	17	receptors	receptor	NOUN
fnp-5842	41	18	(	(	PUNCT
fnp-5842	41	19	ampars	ampar	NOUN
fnp-5842	41	20	)	)	PUNCT
fnp-5842	41	21	.	.	PUNCT
fnp-5842	42	1	we	we	PRON
fnp-5842	42	2	employed	employ	VERB
fnp-5842	42	3	ex	ex	NOUN
fnp-5842	42	4	-	-	NOUN
fnp-5842	42	5	vivo	vivo	ADJ
fnp-5842	42	6	and	and	CCONJ
fnp-5842	42	7	in	in	ADP
fnp-5842	42	8	-	-	PUNCT
fnp-5842	42	9	vitro	vitro	X
fnp-5842	42	10	electrophysiology	electrophysiology	NOUN
fnp-5842	42	11	.	.	PUNCT
fnp-5842	43	1	patch	patch	ADJ
fnp-5842	43	2	-	-	PUNCT
fnp-5842	43	3	clamp	clamp	NOUN
fnp-5842	43	4	recordings	recording	NOUN
fnp-5842	43	5	from	from	ADP
fnp-5842	43	6	melanoma	melanoma	NOUN
fnp-5842	43	7	and	and	CCONJ
fnp-5842	43	8	breast	breast	NOUN
fnp-5842	43	9	cancer	cancer	NOUN
fnp-5842	43	10	cells	cell	NOUN
fnp-5842	43	11	revealed	reveal	VERB
fnp-5842	43	12	spontaneous	spontaneous	ADJ
fnp-5842	43	13	excitatory	excitatory	ADJ
fnp-5842	43	14	postsynaptic	postsynaptic	ADJ
fnp-5842	43	15	currents	current	NOUN
fnp-5842	43	16	(	(	PUNCT
fnp-5842	43	17	sepscs	sepsc	NOUN
fnp-5842	43	18	)	)	PUNCT
fnp-5842	43	19	.	.	PUNCT
fnp-5842	44	1	the	the	DET
fnp-5842	44	2	application	application	NOUN
fnp-5842	44	3	of	of	ADP
fnp-5842	44	4	the	the	DET
fnp-5842	44	5	ampar	ampar	NOUN
fnp-5842	44	6	antagonist	antagonist	NOUN
fnp-5842	44	7	cnqx	cnqx	PROPN
fnp-5842	44	8	inhibited	inhibit	VERB
fnp-5842	44	9	sepscs	sepsc	NOUN
fnp-5842	44	10	,	,	PUNCT
fnp-5842	44	11	confirming	confirm	VERB
fnp-5842	44	12	the	the	DET
fnp-5842	44	13	involvement	involvement	NOUN
fnp-5842	44	14	of	of	ADP
fnp-5842	44	15	ampars	ampar	NOUN
fnp-5842	44	16	.	.	PUNCT
fnp-5842	45	1	in	in	ADP
fnp-5842	45	2	addition	addition	NOUN
fnp-5842	45	3	,	,	PUNCT
fnp-5842	45	4	genetic	genetic	ADJ
fnp-5842	45	5	modification	modification	NOUN
fnp-5842	45	6	and	and	CCONJ
fnp-5842	45	7	pharmacological	pharmacological	ADJ
fnp-5842	45	8	blockade	blockade	NOUN
fnp-5842	45	9	of	of	ADP
fnp-5842	45	10	ampars	ampar	NOUN
fnp-5842	45	11	using	use	VERB
fnp-5842	45	12	the	the	DET
fnp-5842	45	13	approved	approve	VERB
fnp-5842	45	14	antiepileptic	antiepileptic	ADJ
fnp-5842	45	15	drug	drug	NOUN
fnp-5842	45	16	perampanel	perampanel	NOUN
fnp-5842	45	17	in	in	ADP
fnp-5842	45	18	breast	breast	NOUN
fnp-5842	45	19	and	and	CCONJ
fnp-5842	45	20	melanoma	melanoma	NOUN
fnp-5842	45	21	cancer	cancer	NOUN
fnp-5842	45	22	models	model	NOUN
fnp-5842	45	23	led	lead	VERB
fnp-5842	45	24	to	to	ADP
fnp-5842	45	25	a	a	DET
fnp-5842	45	26	reduction	reduction	NOUN
fnp-5842	45	27	in	in	ADP
fnp-5842	45	28	the	the	DET
fnp-5842	45	29	number	number	NOUN
fnp-5842	45	30	of	of	ADP
fnp-5842	45	31	brain	brain	NOUN
fnp-5842	45	32	metastases	metastasis	NOUN
fnp-5842	45	33	and	and	CCONJ
fnp-5842	45	34	overall	overall	ADJ
fnp-5842	45	35	brain	brain	NOUN
fnp-5842	45	36	metastatic	metastatic	ADJ
fnp-5842	45	37	burden	burden	NOUN
fnp-5842	45	38	.	.	PUNCT
fnp-5842	46	1	this	this	DET
fnp-5842	46	2	study	study	NOUN
fnp-5842	46	3	demonstrates	demonstrate	VERB
fnp-5842	46	4	that	that	SCONJ
fnp-5842	46	5	brain	brain	NOUN
fnp-5842	46	6	metastases	metastasis	NOUN
fnp-5842	46	7	can	can	AUX
fnp-5842	46	8	integrate	integrate	VERB
fnp-5842	46	9	into	into	ADP
fnp-5842	46	10	the	the	DET
fnp-5842	46	11	neuronal	neuronal	ADJ
fnp-5842	46	12	network	network	NOUN
fnp-5842	46	13	by	by	ADP
fnp-5842	46	14	forming	form	VERB
fnp-5842	46	15	direct	direct	ADJ
fnp-5842	46	16	chemical	chemical	NOUN
fnp-5842	46	17	synapses	synapsis	NOUN
fnp-5842	46	18	with	with	ADP
fnp-5842	46	19	neurons	neuron	NOUN
fnp-5842	46	20	.	.	PUNCT
fnp-5842	47	1	ampars	ampar	NOUN
fnp-5842	47	2	on	on	ADP
fnp-5842	47	3	cancer	cancer	NOUN
fnp-5842	47	4	cells	cell	NOUN
fnp-5842	47	5	play	play	VERB
fnp-5842	47	6	a	a	DET
fnp-5842	47	7	functional	functional	ADJ
fnp-5842	47	8	role	role	NOUN
fnp-5842	47	9	for	for	ADP
fnp-5842	47	10	brain	brain	NOUN
fnp-5842	47	11	metastatic	metastatic	ADJ
fnp-5842	47	12	progression	progression	NOUN
fnp-5842	47	13	that	that	PRON
fnp-5842	47	14	can	can	AUX
fnp-5842	47	15	be	be	AUX
fnp-5842	47	16	pharmacologically	pharmacologically	ADV
fnp-5842	47	17	targeted	target	VERB
fnp-5842	47	18	.	.	PUNCT
fnp-5842	48	1	this	this	PRON
fnp-5842	48	2	is	be	AUX
fnp-5842	48	3	the	the	DET
fnp-5842	48	4	first	first	ADJ
fnp-5842	48	5	evidence	evidence	NOUN
fnp-5842	48	6	of	of	ADP
fnp-5842	48	7	direct	direct	ADJ
fnp-5842	48	8	synapses	synapsis	NOUN
fnp-5842	48	9	on	on	ADP
fnp-5842	48	10	brain	brain	NOUN
fnp-5842	48	11	metastases	metastasis	NOUN
fnp-5842	48	12	,	,	PUNCT
fnp-5842	48	13	highlighting	highlight	VERB
fnp-5842	48	14	the	the	DET
fnp-5842	48	15	need	need	NOUN
fnp-5842	48	16	for	for	ADP
fnp-5842	48	17	further	further	ADJ
fnp-5842	48	18	characterization	characterization	NOUN
fnp-5842	48	19	of	of	ADP
fnp-5842	48	20	these	these	DET
fnp-5842	48	21	synapses	synapsis	NOUN
fnp-5842	48	22	in	in	ADP
fnp-5842	48	23	brain	brain	NOUN
fnp-5842	48	24	tumor	tumor	NOUN
fnp-5842	48	25	biology	biology	NOUN
fnp-5842	48	26	to	to	PART
fnp-5842	48	27	find	find	VERB
fnp-5842	48	28	novel	novel	ADJ
fnp-5842	48	29	therapeutic	therapeutic	ADJ
fnp-5842	48	30	opportunities	opportunity	NOUN
fnp-5842	48	31	.	.	PUNCT
fnp-5842	49	1	p03	p03	PROPN
fnp-5842	49	2	free	free	PROPN
fnp-5842	49	3	neuropathol	neuropathol	PROPN
fnp-5842	49	4	5:19:8	5:19:8	NUM
fnp-5842	49	5	brain	brain	NOUN
fnp-5842	49	6	invasion	invasion	NOUN
fnp-5842	49	7	in	in	ADP
fnp-5842	49	8	otherwise	otherwise	ADV
fnp-5842	49	9	benign	benign	ADJ
fnp-5842	49	10	meningiomas	meningioma	NOUN
fnp-5842	49	11	:	:	PUNCT
fnp-5842	49	12	molecular	molecular	ADJ
fnp-5842	49	13	characteristics	characteristic	NOUN
fnp-5842	49	14	and	and	CCONJ
fnp-5842	49	15	prognostic	prognostic	ADJ
fnp-5842	49	16	relevance	relevance	NOUN
fnp-5842	49	17	rouzbeh	rouzbeh	NOUN
fnp-5842	49	18	banan1	banan1	PROPN
fnp-5842	49	19	,	,	PUNCT
fnp-5842	49	20	thomas	thomas	PROPN
fnp-5842	49	21	hielscher2	hielscher2	PROPN
fnp-5842	49	22	,	,	PUNCT
fnp-5842	49	23	yiheng	yiheng	PROPN
fnp-5842	49	24	tang1	tang1	PROPN
fnp-5842	49	25	,	,	PUNCT
fnp-5842	49	26	mark	mark	PROPN
fnp-5842	49	27	youngblood3	youngblood3	PROPN
fnp-5842	49	28	,	,	PUNCT
fnp-5842	49	29	daniel	daniel	PROPN
fnp-5842	49	30	schrimpf1	schrimpf1	PROPN
fnp-5842	49	31	,	,	PUNCT
fnp-5842	49	32	kirsten	kirsten	PROPN
fnp-5842	49	33	göbel1	göbel1	PROPN
fnp-5842	49	34	,	,	PUNCT
fnp-5842	49	35	sybren	sybren	PROPN
fnp-5842	49	36	l.n	l.n	PROPN
fnp-5842	49	37	.	.	PROPN
fnp-5842	50	1	maas3,4	maas3,4	PROPN
fnp-5842	50	2	,	,	PUNCT
fnp-5842	50	3	christian	christian	ADJ
fnp-5842	50	4	thomas5	thomas5	PROPN
fnp-5842	50	5	,	,	PUNCT
fnp-5842	50	6	mara	mara	PROPN
fnp-5842	50	7	popovic6	popovic6	PROPN
fnp-5842	50	8	,	,	PUNCT
fnp-5842	50	9	jernej	jernej	PROPN
fnp-5842	50	10	mlakar6	mlakar6	PROPN
fnp-5842	50	11	,	,	PUNCT
fnp-5842	50	12	katharina	katharina	PROPN
fnp-5842	50	13	j.	j.	PROPN
fnp-5842	50	14	weber7	weber7	PROPN
fnp-5842	50	15	,	,	PUNCT
fnp-5842	50	16	karl	karl	PROPN
fnp-5842	50	17	h.	h.	PROPN
fnp-5842	50	18	plate7	plate7	PROPN
fnp-5842	50	19	,	,	PUNCT
fnp-5842	50	20	werner	werner	PROPN
fnp-5842	50	21	paulus5	paulus5	PROPN
fnp-5842	50	22	,	,	PUNCT
fnp-5842	50	23	david	david	PROPN
fnp-5842	50	24	reuss1	reuss1	PROPN
fnp-5842	50	25	,	,	PUNCT
fnp-5842	50	26	miriam	miriam	PROPN
fnp-5842	50	27	ratliff8	ratliff8	PROPN
fnp-5842	50	28	,	,	PUNCT
fnp-5842	50	29	nima	nima	PROPN
fnp-5842	50	30	etminan8	etminan8	PROPN
fnp-5842	50	31	,	,	PUNCT
fnp-5842	50	32	patrick	patrick	PROPN
fnp-5842	50	33	n.	n.	PROPN
fnp-5842	50	34	harter9	harter9	PROPN
fnp-5842	50	35	,	,	PUNCT
fnp-5842	50	36	christian	christian	ADJ
fnp-5842	50	37	hartmann10	hartmann10	NOUN
fnp-5842	50	38	,	,	PUNCT
fnp-5842	50	39	ayça	ayça	PROPN
fnp-5842	50	40	e.	e.	PROPN
fnp-5842	50	41	danyeli11	danyeli11	PROPN
fnp-5842	50	42	,	,	PUNCT
fnp-5842	50	43	yanghao	yanghao	ADJ
fnp-5842	50	44	hou12	hou12	PROPN
fnp-5842	50	45	,	,	PUNCT
fnp-5842	50	46	christel	christel	PROPN
fnp-5842	50	47	herold	herold	PROPN
fnp-5842	50	48	-	-	PUNCT
fnp-5842	50	49	mende13	mende13	PROPN
fnp-5842	50	50	,	,	PUNCT
fnp-5842	50	51	stephen	stephen	PROPN
fnp-5842	50	52	magill	magill	PROPN
fnp-5842	50	53	,	,	PUNCT
fnp-5842	50	54	sandro	sandro	PROPN
fnp-5842	50	55	krieg13	krieg13	PROPN
fnp-5842	50	56	,	,	PUNCT
fnp-5842	50	57	craig	craig	PROPN
fnp-5842	50	58	m.	m.	PROPN
fnp-5842	50	59	horbinski14	horbinski14	PROPN
fnp-5842	50	60	,	,	PUNCT
fnp-5842	50	61	sonika	sonika	NOUN
fnp-5842	50	62	dahiya15	dahiya15	NOUN
fnp-5842	50	63	,	,	PUNCT
fnp-5842	50	64	andreas	andreas	PROPN
fnp-5842	50	65	von	von	PROPN
fnp-5842	50	66	deimling1	deimling1	PROPN
fnp-5842	50	67	,	,	PUNCT
fnp-5842	50	68	bhuvic	bhuvic	ADJ
fnp-5842	50	69	patel16	patel16	NOUN
fnp-5842	50	70	,	,	PUNCT
fnp-5842	50	71	felix	felix	PROPN
fnp-5842	50	72	sahm1	sahm1	NOUN
fnp-5842	50	73	1	1	NUM
fnp-5842	50	74	heidelberg	heidelberg	PROPN
fnp-5842	50	75	university	university	NOUN
fnp-5842	50	76	hospital	hospital	NOUN
fnp-5842	50	77	,	,	PUNCT
fnp-5842	50	78	department	department	NOUN
fnp-5842	50	79	of	of	ADP
fnp-5842	50	80	neuropathology	neuropathology	NOUN
fnp-5842	50	81	and	and	CCONJ
fnp-5842	50	82	dktk	dktk	ADJ
fnp-5842	50	83	,	,	PUNCT
fnp-5842	50	84	dkfz	dkfz	ADJ
fnp-5842	50	85	,	,	PUNCT
fnp-5842	50	86	heidelberg	heidelberg	PROPN
fnp-5842	50	87	,	,	PUNCT
fnp-5842	50	88	germany	germany	PROPN
fnp-5842	50	89	2	2	NUM
fnp-5842	50	90	biostatistics	biostatistic	NOUN
fnp-5842	50	91	,	,	PUNCT
fnp-5842	50	92	dkfz	dkfz	NOUN
fnp-5842	50	93	,	,	PUNCT
fnp-5842	50	94	heidelberg	heidelberg	PROPN
fnp-5842	50	95	,	,	PUNCT
fnp-5842	50	96	germany	germany	PROPN
fnp-5842	50	97	(	(	PUNCT
fnp-5842	50	98	th	th	NOUN
fnp-5842	50	99	)	)	PUNCT
fnp-5842	50	100	3	3	NUM
fnp-5842	50	101	northwestern	northwestern	ADJ
fnp-5842	50	102	university	university	NOUN
fnp-5842	50	103	,	,	PUNCT
fnp-5842	50	104	dept	dept	NOUN
fnp-5842	50	105	.	.	PROPN
fnp-5842	50	106	of	of	ADP
fnp-5842	50	107	neurological	neurological	ADJ
fnp-5842	50	108	surgery	surgery	NOUN
fnp-5842	50	109	chicago	chicago	PROPN
fnp-5842	50	110	,	,	PUNCT
fnp-5842	50	111	il	il	PROPN
fnp-5842	50	112	,	,	PUNCT
fnp-5842	50	113	usa	usa	PROPN
fnp-5842	50	114	4	4	NUM
fnp-5842	50	115	department	department	NOUN
fnp-5842	50	116	of	of	ADP
fnp-5842	50	117	pathology	pathology	PROPN
fnp-5842	50	118	,	,	PUNCT
fnp-5842	50	119	leiden	leiden	PROPN
fnp-5842	50	120	university	university	PROPN
fnp-5842	50	121	medical	medical	ADJ
fnp-5842	50	122	center	center	NOUN
fnp-5842	50	123	,	,	PUNCT
fnp-5842	50	124	leiden	leiden	PROPN
fnp-5842	50	125	,	,	PUNCT
fnp-5842	50	126	netherlands	netherlands	PROPN
fnp-5842	50	127	and	and	CCONJ
fnp-5842	50	128	department	department	PROPN
fnp-5842	50	129	of	of	ADP
fnp-5842	50	130	pathology	pathology	PROPN
fnp-5842	50	131	,	,	PUNCT
fnp-5842	50	132	erasmus	erasmus	PROPN
fnp-5842	50	133	mc	mc	PROPN
fnp-5842	50	134	cancer	cancer	PROPN
fnp-5842	50	135	institute	institute	PROPN
fnp-5842	50	136	,	,	PUNCT
fnp-5842	50	137	university	university	PROPN
fnp-5842	50	138	medical	medical	ADJ
fnp-5842	50	139	center	center	NOUN
fnp-5842	50	140	rotterdam	rotterdam	PROPN
fnp-5842	50	141	,	,	PUNCT
fnp-5842	50	142	rotterdam	rotterdam	PROPN
fnp-5842	50	143	,	,	PUNCT
fnp-5842	50	144	the	the	DET
fnp-5842	50	145	netherlands	netherlands	PROPN
fnp-5842	50	146	5	5	NUM
fnp-5842	50	147	university	university	NOUN
fnp-5842	50	148	hospital	hospital	NOUN
fnp-5842	50	149	münster	münster	NOUN
fnp-5842	50	150	,	,	PUNCT
fnp-5842	50	151	institute	institute	NOUN
fnp-5842	50	152	of	of	ADP
fnp-5842	50	153	neuropathology	neuropathology	NOUN
fnp-5842	50	154	,	,	PUNCT
fnp-5842	50	155	münster	münster	PROPN
fnp-5842	50	156	,	,	PUNCT
fnp-5842	50	157	germany	germany	PROPN
fnp-5842	50	158	6	6	NUM
fnp-5842	50	159	university	university	PROPN
fnp-5842	50	160	of	of	ADP
fnp-5842	50	161	ljubljana	ljubljana	PROPN
fnp-5842	50	162	,	,	PUNCT
fnp-5842	50	163	faculty	faculty	NOUN
fnp-5842	50	164	of	of	ADP
fnp-5842	50	165	medicine	medicine	NOUN
fnp-5842	50	166	,	,	PUNCT
fnp-5842	50	167	institute	institute	NOUN
fnp-5842	50	168	of	of	ADP
fnp-5842	50	169	pathology	pathology	PROPN
fnp-5842	50	170	,	,	PUNCT
fnp-5842	50	171	ljubljana	ljubljana	PROPN
fnp-5842	50	172	,	,	PUNCT
fnp-5842	50	173	slovenia	slovenia	PROPN
fnp-5842	50	174	7	7	NUM
fnp-5842	50	175	goethe	goethe	PROPN
fnp-5842	50	176	university	university	NOUN
fnp-5842	50	177	,	,	PUNCT
fnp-5842	50	178	university	university	NOUN
fnp-5842	50	179	hospital	hospital	NOUN
fnp-5842	50	180	,	,	PUNCT
fnp-5842	50	181	institute	institute	NOUN
fnp-5842	50	182	of	of	ADP
fnp-5842	50	183	neurology	neurology	NOUN
fnp-5842	50	184	(	(	PUNCT
fnp-5842	50	185	edinger	edinger	PROPN
fnp-5842	50	186	institute	institute	PROPN
fnp-5842	50	187	)	)	PUNCT
fnp-5842	50	188	,	,	PUNCT
fnp-5842	50	189	institute	institute	NOUN
fnp-5842	50	190	of	of	ADP
fnp-5842	50	191	neurology	neurology	NOUN
fnp-5842	50	192	,	,	PUNCT
fnp-5842	50	193	frankfurt	frankfurt	PROPN
fnp-5842	50	194	,	,	PUNCT
fnp-5842	50	195	germany	germany	PROPN
fnp-5842	50	196	8	8	NUM
fnp-5842	50	197	university	university	NOUN
fnp-5842	50	198	hospital	hospital	NOUN
fnp-5842	50	199	mannheim	mannheim	PROPN
fnp-5842	50	200	,	,	PUNCT
fnp-5842	50	201	dept	dept	NOUN
fnp-5842	50	202	.	.	PROPN
fnp-5842	50	203	of	of	ADP
fnp-5842	50	204	neurosurgery	neurosurgery	PROPN
fnp-5842	50	205	,	,	PUNCT
fnp-5842	50	206	mannheim	mannheim	PROPN
fnp-5842	50	207	,	,	PUNCT
fnp-5842	50	208	germany	germany	PROPN
fnp-5842	50	209	9	9	NUM
fnp-5842	50	210	center	center	NOUN
fnp-5842	50	211	for	for	ADP
fnp-5842	50	212	neuropathology	neuropathology	NOUN
fnp-5842	50	213	and	and	CCONJ
fnp-5842	50	214	prion	prion	NOUN
fnp-5842	50	215	research	research	NOUN
fnp-5842	50	216	,	,	PUNCT
fnp-5842	50	217	faculty	faculty	NOUN
fnp-5842	50	218	of	of	ADP
fnp-5842	50	219	medicine	medicine	NOUN
fnp-5842	50	220	,	,	PUNCT
fnp-5842	50	221	ludwig	ludwig	PROPN
fnp-5842	50	222	-	-	PUNCT
fnp-5842	50	223	maximilians	maximilians	PROPN
fnp-5842	50	224	-	-	PUNCT
fnp-5842	50	225	university	university	NOUN
fnp-5842	50	226	munich	munich	PROPN
fnp-5842	50	227	,	,	PUNCT
fnp-5842	50	228	munich	munich	PROPN
fnp-5842	50	229	,	,	PUNCT
fnp-5842	50	230	germany	germany	PROPN
fnp-5842	50	231	10	10	NUM
fnp-5842	50	232	hannover	hannover	PROPN
fnp-5842	50	233	medical	medical	PROPN
fnp-5842	50	234	school	school	PROPN
fnp-5842	50	235	,	,	PUNCT
fnp-5842	50	236	dept	dept	NOUN
fnp-5842	50	237	.	.	PROPN
fnp-5842	50	238	of	of	ADP
fnp-5842	50	239	neuropathology	neuropathology	NOUN
fnp-5842	50	240	,	,	PUNCT
fnp-5842	50	241	hannover	hannover	PROPN
fnp-5842	50	242	,	,	PUNCT
fnp-5842	50	243	germany	germany	PROPN
fnp-5842	50	244	11	11	NUM
fnp-5842	50	245	acibadem	acibadem	PROPN
fnp-5842	50	246	mehmet	mehmet	PROPN
fnp-5842	50	247	ali	ali	PROPN
fnp-5842	51	1	aydinlar	aydinlar	PROPN
fnp-5842	51	2	university	university	PROPN
fnp-5842	51	3	,	,	PUNCT
fnp-5842	51	4	dept	dept	NOUN
fnp-5842	51	5	.	.	PROPN
fnp-5842	51	6	of	of	ADP
fnp-5842	51	7	pathology	pathology	PROPN
fnp-5842	51	8	,	,	PUNCT
fnp-5842	51	9	istanbul	istanbul	PROPN
fnp-5842	51	10	,	,	PUNCT
fnp-5842	51	11	turkey	turkey	NOUN
fnp-5842	51	12	12	12	NUM
fnp-5842	51	13	chongqing	chongqing	PROPN
fnp-5842	51	14	medical	medical	ADJ
fnp-5842	51	15	university	university	PROPN
fnp-5842	51	16	,	,	PUNCT
fnp-5842	51	17	dept	dept	NOUN
fnp-5842	51	18	.	.	PROPN
fnp-5842	51	19	of	of	ADP
fnp-5842	51	20	pathology	pathology	PROPN
fnp-5842	51	21	,	,	PUNCT
fnp-5842	51	22	chongqing	chongqing	PROPN
fnp-5842	51	23	,	,	PUNCT
fnp-5842	51	24	p.	p.	PROPN
fnp-5842	51	25	r.	r.	PROPN
fnp-5842	52	1	china	china	PROPN
fnp-5842	52	2	13	13	NUM
fnp-5842	52	3	university	university	PROPN
fnp-5842	52	4	hospital	hospital	NOUN
fnp-5842	52	5	heidelberg	heidelberg	PROPN
fnp-5842	52	6	,	,	PUNCT
fnp-5842	52	7	dept	dept	NOUN
fnp-5842	52	8	.	.	PROPN
fnp-5842	52	9	of	of	ADP
fnp-5842	52	10	neurosurgery	neurosurgery	PROPN
fnp-5842	52	11	,	,	PUNCT
fnp-5842	52	12	heidelberg	heidelberg	PROPN
fnp-5842	52	13	,	,	PUNCT
fnp-5842	52	14	germany	germany	PROPN
fnp-5842	52	15	14	14	NUM
fnp-5842	52	16	northwestern	northwestern	PROPN
fnp-5842	52	17	university	university	NOUN
fnp-5842	52	18	,	,	PUNCT
fnp-5842	52	19	department	department	NOUN
fnp-5842	52	20	of	of	ADP
fnp-5842	52	21	pathology	pathology	PROPN
fnp-5842	52	22	,	,	PUNCT
fnp-5842	52	23	chicago	chicago	PROPN
fnp-5842	52	24	,	,	PUNCT
fnp-5842	52	25	il	il	PROPN
fnp-5842	52	26	,	,	PUNCT
fnp-5842	52	27	usa	usa	PROPN
fnp-5842	52	28	15	15	NUM
fnp-5842	52	29	washington	washington	PROPN
fnp-5842	52	30	university	university	PROPN
fnp-5842	52	31	school	school	NOUN
fnp-5842	52	32	of	of	ADP
fnp-5842	52	33	medicine	medicine	NOUN
fnp-5842	52	34	,	,	PUNCT
fnp-5842	52	35	div	div	PROPN
fnp-5842	52	36	.	.	PROPN
fnp-5842	52	37	of	of	ADP
fnp-5842	52	38	neuropathology	neuropathology	NOUN
fnp-5842	52	39	,	,	PUNCT
fnp-5842	52	40	dept	dept	NOUN
fnp-5842	52	41	.	.	PROPN
fnp-5842	52	42	of	of	ADP
fnp-5842	52	43	pathology	pathology	NOUN
fnp-5842	52	44	and	and	CCONJ
fnp-5842	52	45	immunology	immunology	NOUN
fnp-5842	52	46	,	,	PUNCT
fnp-5842	52	47	st	st	PROPN
fnp-5842	52	48	.	.	PROPN
fnp-5842	52	49	louis	louis	PROPN
fnp-5842	52	50	,	,	PUNCT
fnp-5842	52	51	mo	mo	PROPN
fnp-5842	52	52	,	,	PUNCT
fnp-5842	52	53	usa	usa	PROPN
fnp-5842	52	54	16	16	NUM
fnp-5842	52	55	washington	washington	PROPN
fnp-5842	52	56	university	university	PROPN
fnp-5842	52	57	school	school	NOUN
fnp-5842	52	58	of	of	ADP
fnp-5842	52	59	medicine	medicine	NOUN
fnp-5842	52	60	,	,	PUNCT
fnp-5842	52	61	dept	dept	NOUN
fnp-5842	52	62	.	.	PROPN
fnp-5842	52	63	of	of	ADP
fnp-5842	52	64	neurological	neurological	ADJ
fnp-5842	52	65	surgery	surgery	NOUN
fnp-5842	52	66	,	,	PUNCT
fnp-5842	52	67	st	st	PROPN
fnp-5842	52	68	.	.	PROPN
fnp-5842	52	69	louis	louis	PROPN
fnp-5842	52	70	,	,	PUNCT
fnp-5842	52	71	mo	mo	PROPN
fnp-5842	52	72	,	,	PUNCT
fnp-5842	52	73	usa	usa	PROPN
fnp-5842	52	74	introduction	introduction	NOUN
fnp-5842	52	75	:	:	PUNCT
fnp-5842	52	76	the	the	DET
fnp-5842	52	77	prognostic	prognostic	ADJ
fnp-5842	52	78	value	value	NOUN
fnp-5842	52	79	of	of	ADP
fnp-5842	52	80	brain	brain	NOUN
fnp-5842	52	81	invasion	invasion	NOUN
fnp-5842	52	82	(	(	PUNCT
fnp-5842	52	83	bi	bi	NOUN
fnp-5842	52	84	)	)	PUNCT
fnp-5842	52	85	in	in	ADP
fnp-5842	52	86	meningiomas	meningioma	NOUN
fnp-5842	52	87	and	and	CCONJ
fnp-5842	52	88	thus	thus	ADV
fnp-5842	52	89	the	the	DET
fnp-5842	52	90	grading	grading	NOUN
fnp-5842	52	91	of	of	ADP
fnp-5842	52	92	these	these	DET
fnp-5842	52	93	tumors	tumor	NOUN
fnp-5842	52	94	has	have	AUX
fnp-5842	52	95	controversially	controversially	ADV
fnp-5842	52	96	been	be	AUX
fnp-5842	52	97	discussed	discuss	VERB
fnp-5842	52	98	for	for	ADP
fnp-5842	52	99	decades	decade	NOUN
fnp-5842	52	100	.	.	PUNCT
fnp-5842	53	1	the	the	DET
fnp-5842	53	2	2016	2016	NUM
fnp-5842	53	3	revised	revise	VERB
fnp-5842	53	4	4th	4th	ADJ
fnp-5842	53	5	edition	edition	NOUN
fnp-5842	53	6	of	of	ADP
fnp-5842	53	7	who	who	PRON
fnp-5842	53	8	classification	classification	NOUN
fnp-5842	53	9	of	of	ADP
fnp-5842	53	10	cns	cns	PROPN
fnp-5842	53	11	tumors	tumor	NOUN
fnp-5842	53	12	defined	define	VERB
fnp-5842	53	13	bi	bi	NOUN
fnp-5842	53	14	as	as	ADP
fnp-5842	53	15	a	a	DET
fnp-5842	53	16	stand	stand	VERB
fnp-5842	53	17	-	-	PUNCT
fnp-5842	53	18	alone	alone	ADV
fnp-5842	53	19	criterion	criterion	NOUN
fnp-5842	53	20	for	for	ADP
fnp-5842	53	21	grade	grade	NOUN
fnp-5842	53	22	2	2	NUM
fnp-5842	53	23	.	.	PUNCT
fnp-5842	54	1	still	still	ADV
fnp-5842	54	2	,	,	PUNCT
fnp-5842	54	3	the	the	DET
fnp-5842	54	4	data	datum	NOUN
fnp-5842	54	5	published	publish	VERB
fnp-5842	54	6	since	since	SCONJ
fnp-5842	54	7	then	then	ADV
fnp-5842	54	8	have	have	AUX
fnp-5842	54	9	been	be	AUX
fnp-5842	54	10	inconsistent	inconsistent	ADJ
fnp-5842	54	11	.	.	PUNCT
fnp-5842	55	1	in	in	ADP
fnp-5842	55	2	the	the	DET
fnp-5842	55	3	2021	2021	NUM
fnp-5842	55	4	classification	classification	NOUN
fnp-5842	55	5	cns5	cns5	PROPN
fnp-5842	55	6	,	,	PUNCT
fnp-5842	55	7	brain	brain	NOUN
fnp-5842	55	8	-	-	PUNCT
fnp-5842	55	9	invasive	invasive	ADJ
fnp-5842	55	10	otherwise	otherwise	ADV
fnp-5842	55	11	benign	benign	ADJ
fnp-5842	55	12	meningiomas	meningioma	NOUN
fnp-5842	55	13	(	(	PUNCT
fnp-5842	55	14	biob	biob	ADV
fnp-5842	55	15	)	)	PUNCT
fnp-5842	55	16	are	be	AUX
fnp-5842	55	17	still	still	ADV
fnp-5842	55	18	graded	grade	VERB
fnp-5842	55	19	as	as	ADP
fnp-5842	55	20	cns	cns	PROPN
fnp-5842	55	21	who	who	PRON
fnp-5842	55	22	grade	grade	NOUN
fnp-5842	55	23	2	2	NUM
fnp-5842	55	24	,	,	PUNCT
fnp-5842	55	25	yet	yet	ADV
fnp-5842	55	26	with	with	ADP
fnp-5842	55	27	emphasis	emphasis	NOUN
fnp-5842	55	28	on	on	ADP
fnp-5842	55	29	the	the	DET
fnp-5842	55	30	lingering	linger	VERB
fnp-5842	55	31	controversy	controversy	NOUN
fnp-5842	55	32	.	.	PUNCT
fnp-5842	56	1	materials	material	NOUN
fnp-5842	56	2	and	and	CCONJ
fnp-5842	56	3	methods	method	NOUN
fnp-5842	56	4	:	:	PUNCT
fnp-5842	56	5	a	a	DET
fnp-5842	56	6	multicentric	multicentric	ADJ
fnp-5842	56	7	series	series	NOUN
fnp-5842	56	8	of	of	ADP
fnp-5842	56	9	304	304	NUM
fnp-5842	56	10	brain	brain	NOUN
fnp-5842	56	11	-	-	PUNCT
fnp-5842	56	12	invasive	invasive	ADJ
fnp-5842	56	13	cases	case	NOUN
fnp-5842	56	14	was	be	AUX
fnp-5842	56	15	analyzed	analyze	VERB
fnp-5842	56	16	.	.	PUNCT
fnp-5842	57	1	673	673	NUM
fnp-5842	57	2	meningiomas	meningioma	NOUN
fnp-5842	57	3	from	from	ADP
fnp-5842	57	4	previous	previous	ADJ
fnp-5842	57	5	studies	study	NOUN
fnp-5842	57	6	were	be	AUX
fnp-5842	57	7	used	use	VERB
fnp-5842	57	8	for	for	ADP
fnp-5842	57	9	comparison	comparison	NOUN
fnp-5842	57	10	.	.	PUNCT
fnp-5842	58	1	dna	dna	PROPN
fnp-5842	58	2	-	-	PUNCT
fnp-5842	58	3	methylation	methylation	NOUN
fnp-5842	58	4	classification	classification	NOUN
fnp-5842	58	5	,	,	PUNCT
fnp-5842	58	6	cnv	cnv	NOUN
fnp-5842	58	7	-	-	NOUN
fnp-5842	58	8	profiling	profiling	NOUN
fnp-5842	58	9	(	(	PUNCT
fnp-5842	58	10	both	both	PRON
fnp-5842	58	11	epic	epic	ADJ
fnp-5842	58	12	,	,	PUNCT
fnp-5842	58	13	v12	v12	VERB
fnp-5842	58	14	)	)	PUNCT
fnp-5842	58	15	and	and	CCONJ
fnp-5842	58	16	sequencing	sequence	VERB
fnp-5842	58	17	data	datum	NOUN
fnp-5842	58	18	(	(	PUNCT
fnp-5842	58	19	panel	panel	NOUN
fnp-5842	58	20	/	/	SYM
fnp-5842	58	21	whole	whole	ADJ
fnp-5842	58	22	-	-	PUNCT
fnp-5842	58	23	exome	exome	NOUN
fnp-5842	58	24	)	)	PUNCT
fnp-5842	58	25	were	be	AUX
fnp-5842	58	26	generated	generate	VERB
fnp-5842	58	27	.	.	PUNCT
fnp-5842	59	1	kaplan	kaplan	PROPN
fnp-5842	59	2	-	-	PROPN
fnp-5842	59	3	mayer	mayer	PROPN
fnp-5842	59	4	analysis	analysis	NOUN
fnp-5842	59	5	and	and	CCONJ
fnp-5842	59	6	multivariate	multivariate	NOUN
fnp-5842	59	7	cox	cox	PROPN
fnp-5842	59	8	regression	regression	PROPN
fnp-5842	59	9	were	be	AUX
fnp-5842	59	10	applied	apply	VERB
fnp-5842	59	11	to	to	PART
fnp-5842	59	12	analyze	analyze	VERB
fnp-5842	59	13	clinical	clinical	ADJ
fnp-5842	59	14	outcomes	outcome	NOUN
fnp-5842	59	15	.	.	PUNCT
fnp-5842	60	1	results	result	NOUN
fnp-5842	60	2	:	:	PUNCT
fnp-5842	60	3	biob	biob	PROPN
fnp-5842	60	4	cases	case	NOUN
fnp-5842	60	5	were	be	AUX
fnp-5842	60	6	more	more	ADV
fnp-5842	60	7	frequently	frequently	ADV
fnp-5842	60	8	of	of	ADP
fnp-5842	60	9	male	male	ADJ
fnp-5842	60	10	sex	sex	NOUN
fnp-5842	60	11	and	and	CCONJ
fnp-5842	60	12	showed	show	VERB
fnp-5842	60	13	chr14q	chr14q	PRON
fnp-5842	60	14	loss	loss	NOUN
fnp-5842	60	15	compared	compare	VERB
fnp-5842	60	16	to	to	ADP
fnp-5842	60	17	non	non	ADJ
fnp-5842	60	18	-	-	ADJ
fnp-5842	60	19	invasive	invasive	ADJ
fnp-5842	60	20	cns	cns	NOUN
fnp-5842	60	21	who	who	PRON
fnp-5842	60	22	grade	grade	VERB
fnp-5842	60	23	1	1	NUM
fnp-5842	60	24	tumors	tumor	NOUN
fnp-5842	60	25	,	,	PUNCT
fnp-5842	60	26	(	(	PUNCT
fnp-5842	60	27	p	p	X
fnp-5842	60	28	 	 	SPACE
fnp-5842	60	29	=	=	NOUN
fnp-5842	60	30	 	 	SPACE
fnp-5842	60	31	0.027	0.027	NUM
fnp-5842	60	32	and	and	CCONJ
fnp-5842	60	33	p	p	X
fnp-5842	60	34	 	 	SPACE
fnp-5842	60	35	=	=	NOUN
fnp-5842	60	36	 	 	SPACE
fnp-5842	60	37	0.006	0.006	NUM
fnp-5842	60	38	respectively	respectively	ADV
fnp-5842	60	39	)	)	PUNCT
fnp-5842	60	40	.	.	PUNCT
fnp-5842	61	1	biob	biob	PROPN
fnp-5842	61	2	had	have	VERB
fnp-5842	61	3	shorter	short	ADJ
fnp-5842	61	4	pfs	pfs	PROPN
fnp-5842	61	5	than	than	ADP
fnp-5842	61	6	cns	cns	PROPN
fnp-5842	61	7	who	who	PRON
fnp-5842	61	8	grade	grade	VERB
fnp-5842	61	9	1	1	NUM
fnp-5842	61	10	(	(	PUNCT
fnp-5842	61	11	p	p	NOUN
fnp-5842	61	12	 	 	SPACE
fnp-5842	61	13	=	=	NOUN
fnp-5842	61	14	 	 	SPACE
fnp-5842	61	15	0.003	0.003	NUM
fnp-5842	61	16	)	)	PUNCT
fnp-5842	61	17	,	,	PUNCT
fnp-5842	61	18	yet	yet	CCONJ
fnp-5842	61	19	more	more	ADV
fnp-5842	61	20	favorable	favorable	ADJ
fnp-5842	61	21	outcome	outcome	NOUN
fnp-5842	61	22	than	than	ADP
fnp-5842	61	23	non	non	ADJ
fnp-5842	61	24	-	-	ADJ
fnp-5842	61	25	invasive	invasive	ADJ
fnp-5842	61	26	cns	cns	NOUN
fnp-5842	61	27	who	who	PRON
fnp-5842	61	28	grade	grade	VERB
fnp-5842	61	29	2	2	NUM
fnp-5842	61	30	cases	case	NOUN
fnp-5842	61	31	(	(	PUNCT
fnp-5842	61	32	p	p	NOUN
fnp-5842	61	33	 	 	SPACE
fnp-5842	61	34	=	=	NOUN
fnp-5842	61	35	 	 	SPACE
fnp-5842	61	36	0.006	0.006	NUM
fnp-5842	61	37	)	)	PUNCT
fnp-5842	61	38	.	.	PUNCT
fnp-5842	62	1	in	in	ADP
fnp-5842	62	2	multivariate	multivariate	NOUN
fnp-5842	62	3	analyses	analysis	NOUN
fnp-5842	62	4	considering	consider	VERB
fnp-5842	62	5	sex	sex	NOUN
fnp-5842	62	6	,	,	PUNCT
fnp-5842	62	7	who	who	PRON
fnp-5842	62	8	grade	grade	VERB
fnp-5842	62	9	,	,	PUNCT
fnp-5842	62	10	methylation	methylation	NOUN
fnp-5842	62	11	families	family	NOUN
fnp-5842	62	12	(	(	PUNCT
fnp-5842	62	13	intermediate	intermediate	ADJ
fnp-5842	62	14	,	,	PUNCT
fnp-5842	62	15	malignant	malignant	ADJ
fnp-5842	62	16	)	)	PUNCT
fnp-5842	62	17	and	and	CCONJ
fnp-5842	62	18	prognostically	prognostically	ADV
fnp-5842	62	19	relevant	relevant	ADJ
fnp-5842	62	20	cnvs	cnvs	NOUN
fnp-5842	62	21	,	,	PUNCT
fnp-5842	62	22	bi	bi	PROPN
fnp-5842	62	23	was	be	AUX
fnp-5842	62	24	an	an	DET
fnp-5842	62	25	independent	independent	ADJ
fnp-5842	62	26	risk	risk	NOUN
fnp-5842	62	27	factor	factor	NOUN
fnp-5842	62	28	for	for	ADP
fnp-5842	62	29	shorter	short	ADJ
fnp-5842	62	30	pfs	pfs	PROPN
fnp-5842	62	31	(	(	PUNCT
fnp-5842	62	32	hr	hr	NOUN
fnp-5842	62	33	:	:	PUNCT
fnp-5842	62	34	1.73	1.73	NUM
fnp-5842	62	35	;	;	PUNCT
fnp-5842	62	36	95	95	NUM
fnp-5842	62	37	 	 	SPACE
fnp-5842	62	38	%	%	NOUN
fnp-5842	62	39	-ci	-ci	ADJ
fnp-5842	62	40	:	:	PUNCT
fnp-5842	62	41	1.34–2.22	1.34–2.22	NUM
fnp-5842	62	42	;	;	PUNCT
fnp-5842	62	43	p	p	X
fnp-5842	62	44	 	 	SPACE
fnp-5842	62	45	<	<	X
fnp-5842	62	46	 	 	SPACE
fnp-5842	62	47	0.001	0.001	NUM
fnp-5842	62	48	)	)	PUNCT
fnp-5842	62	49	.	.	PUNCT
fnp-5842	63	1	conclusion	conclusion	NOUN
fnp-5842	63	2	:	:	PUNCT
fnp-5842	63	3	in	in	ADP
fnp-5842	63	4	this	this	DET
fnp-5842	63	5	study	study	NOUN
fnp-5842	63	6	,	,	PUNCT
fnp-5842	63	7	bi	bi	NOUN
fnp-5842	63	8	confers	confer	NOUN
fnp-5842	63	9	an	an	DET
fnp-5842	63	10	independently	independently	ADV
fnp-5842	63	11	higher	high	ADJ
fnp-5842	63	12	risk	risk	NOUN
fnp-5842	63	13	of	of	ADP
fnp-5842	63	14	reduced	reduce	VERB
fnp-5842	63	15	pfs	pfs	PROPN
fnp-5842	63	16	even	even	ADV
fnp-5842	63	17	among	among	ADP
fnp-5842	63	18	otherwise	otherwise	ADV
fnp-5842	63	19	cns	cns	PROPN
fnp-5842	63	20	who	who	PRON
fnp-5842	63	21	grade	grade	VERB
fnp-5842	63	22	1	1	NUM
fnp-5842	63	23	cases	case	NOUN
fnp-5842	63	24	.	.	PUNCT
fnp-5842	64	1	however	however	ADV
fnp-5842	64	2	,	,	PUNCT
fnp-5842	64	3	the	the	DET
fnp-5842	64	4	risk	risk	NOUN
fnp-5842	64	5	and	and	CCONJ
fnp-5842	64	6	outcome	outcome	NOUN
fnp-5842	64	7	align	align	VERB
fnp-5842	64	8	neither	neither	CCONJ
fnp-5842	64	9	with	with	ADP
fnp-5842	64	10	cns	cns	PROPN
fnp-5842	64	11	who	who	PRON
fnp-5842	64	12	grade	grade	VERB
fnp-5842	64	13	1	1	NUM
fnp-5842	64	14	nor	nor	CCONJ
fnp-5842	64	15	2	2	NUM
fnp-5842	64	16	in	in	ADP
fnp-5842	64	17	our	our	PRON
fnp-5842	64	18	reference	reference	NOUN
fnp-5842	64	19	cohort	cohort	NOUN
fnp-5842	64	20	.	.	PUNCT
fnp-5842	65	1	further	further	ADJ
fnp-5842	65	2	analyses	analysis	NOUN
fnp-5842	65	3	are	be	AUX
fnp-5842	65	4	warranted	warrant	VERB
fnp-5842	65	5	for	for	ADP
fnp-5842	65	6	alternative	alternative	ADJ
fnp-5842	65	7	risk	risk	NOUN
fnp-5842	65	8	stratification	stratification	NOUN
fnp-5842	65	9	and	and	CCONJ
fnp-5842	65	10	data	datum	NOUN
fnp-5842	65	11	validation	validation	NOUN
fnp-5842	65	12	.	.	PUNCT
fnp-5842	66	1	p04	p04	PROPN
fnp-5842	66	2	free	free	ADJ
fnp-5842	66	3	neuropathol	neuropathol	NOUN
fnp-5842	66	4	5:19:10	5:19:10	DET
fnp-5842	66	5	electrophysiological	electrophysiological	ADJ
fnp-5842	66	6	characterization	characterization	NOUN
fnp-5842	66	7	of	of	ADP
fnp-5842	66	8	slow	slow	ADJ
fnp-5842	66	9	inward	inward	ADJ
fnp-5842	66	10	currents	current	NOUN
fnp-5842	66	11	in	in	ADP
fnp-5842	66	12	glioblastoma	glioblastoma	NOUN
fnp-5842	66	13	tamara	tamara	PROPN
fnp-5842	66	14	chopurian1	chopurian1	PROPN
fnp-5842	66	15	,	,	PUNCT
fnp-5842	66	16	frank	frank	PROPN
fnp-5842	66	17	winkler2,3	winkler2,3	PROPN
fnp-5842	66	18	,	,	PUNCT
fnp-5842	66	19	thomas	thomas	PROPN
fnp-5842	66	20	kuner1	kuner1	PROPN
fnp-5842	66	21	,	,	PUNCT
fnp-5842	66	22	varun	varun	PROPN
fnp-5842	66	23	venkataramani1,2,3	venkataramani1,2,3	NOUN
fnp-5842	66	24	1	1	NUM
fnp-5842	66	25	department	department	NOUN
fnp-5842	66	26	of	of	ADP
fnp-5842	66	27	functional	functional	ADJ
fnp-5842	66	28	neuroanatomy	neuroanatomy	NOUN
fnp-5842	66	29	,	,	PUNCT
fnp-5842	66	30	institute	institute	NOUN
fnp-5842	66	31	for	for	ADP
fnp-5842	66	32	anatomy	anatomy	NOUN
fnp-5842	66	33	and	and	CCONJ
fnp-5842	66	34	cell	cell	NOUN
fnp-5842	66	35	biology	biology	NOUN
fnp-5842	66	36	,	,	PUNCT
fnp-5842	66	37	heidelberg	heidelberg	PROPN
fnp-5842	66	38	university	university	PROPN
fnp-5842	66	39	,	,	PUNCT
fnp-5842	66	40	germany	germany	PROPN
fnp-5842	66	41	2	2	NUM
fnp-5842	66	42	neurology	neurology	NOUN
fnp-5842	66	43	clinic	clinic	NOUN
fnp-5842	66	44	and	and	CCONJ
fnp-5842	66	45	national	national	ADJ
fnp-5842	66	46	center	center	NOUN
fnp-5842	66	47	for	for	ADP
fnp-5842	66	48	tumor	tumor	NOUN
fnp-5842	66	49	diseases	disease	NOUN
fnp-5842	66	50	,	,	PUNCT
fnp-5842	66	51	university	university	NOUN
fnp-5842	66	52	hospital	hospital	NOUN
fnp-5842	66	53	heidelberg	heidelberg	PROPN
fnp-5842	66	54	,	,	PUNCT
fnp-5842	66	55	germany	germany	PROPN
fnp-5842	66	56	3	3	NUM
fnp-5842	66	57	clinical	clinical	ADJ
fnp-5842	66	58	cooperation	cooperation	NOUN
fnp-5842	66	59	unit	unit	NOUN
fnp-5842	66	60	neurooncology	neurooncology	NOUN
fnp-5842	66	61	,	,	PUNCT
fnp-5842	66	62	german	german	ADJ
fnp-5842	66	63	cancer	cancer	NOUN
fnp-5842	66	64	consortium	consortium	NOUN
fnp-5842	66	65	(	(	PUNCT
fnp-5842	66	66	dktk	dktk	NOUN
fnp-5842	66	67	)	)	PUNCT
fnp-5842	66	68	,	,	PUNCT
fnp-5842	66	69	german	german	ADJ
fnp-5842	66	70	cancer	cancer	NOUN
fnp-5842	66	71	research	research	NOUN
fnp-5842	66	72	center	center	NOUN
fnp-5842	66	73	(	(	PUNCT
fnp-5842	66	74	dkfz	dkfz	PROPN
fnp-5842	66	75	)	)	PUNCT
fnp-5842	66	76	,	,	PUNCT
fnp-5842	66	77	heidelberg	heidelberg	PROPN
fnp-5842	66	78	,	,	PUNCT
fnp-5842	66	79	germany	germany	PROPN
fnp-5842	66	80	introduction	introduction	NOUN
fnp-5842	66	81	:	:	PUNCT
fnp-5842	66	82	glioblastomas	glioblastoma	NOUN
fnp-5842	66	83	are	be	AUX
fnp-5842	66	84	incurable	incurable	ADJ
fnp-5842	66	85	primary	primary	ADJ
fnp-5842	66	86	brain	brain	NOUN
fnp-5842	66	87	tumors	tumor	NOUN
fnp-5842	66	88	colonizing	colonize	VERB
fnp-5842	66	89	the	the	DET
fnp-5842	66	90	entire	entire	ADJ
fnp-5842	66	91	brain	brain	NOUN
fnp-5842	66	92	.	.	PUNCT
fnp-5842	67	1	long	long	ADJ
fnp-5842	67	2	membrane	membrane	NOUN
fnp-5842	67	3	protrusions	protrusion	NOUN
fnp-5842	67	4	called	call	VERB
fnp-5842	67	5	tumor	tumor	NOUN
fnp-5842	67	6	microtubes	microtube	NOUN
fnp-5842	67	7	(	(	PUNCT
fnp-5842	67	8	tms	tms	PROPN
fnp-5842	67	9	)	)	PUNCT
fnp-5842	67	10	as	as	ADV
fnp-5842	67	11	well	well	ADV
fnp-5842	67	12	synapses	synapse	VERB
fnp-5842	67	13	on	on	ADP
fnp-5842	67	14	glioblastoma	glioblastoma	NOUN
fnp-5842	67	15	cells	cell	NOUN
fnp-5842	67	16	(	(	PUNCT
fnp-5842	67	17	gbcs	gbc	NOUN
fnp-5842	67	18	)	)	PUNCT
fnp-5842	67	19	contribute	contribute	VERB
fnp-5842	67	20	to	to	ADP
fnp-5842	67	21	glioma	glioma	ADJ
fnp-5842	67	22	progression	progression	NOUN
fnp-5842	67	23	.	.	PUNCT
fnp-5842	68	1	in	in	ADP
fnp-5842	68	2	a	a	DET
fnp-5842	68	3	subset	subset	NOUN
fnp-5842	68	4	of	of	ADP
fnp-5842	68	5	gbcs	gbcs	NOUN
fnp-5842	68	6	neuronal	neuronal	ADJ
fnp-5842	68	7	input	input	NOUN
fnp-5842	68	8	leads	lead	VERB
fnp-5842	68	9	to	to	ADP
fnp-5842	68	10	excitatory	excitatory	ADJ
fnp-5842	68	11	postsynaptic	postsynaptic	ADJ
fnp-5842	68	12	currents	current	NOUN
fnp-5842	68	13	(	(	PUNCT
fnp-5842	68	14	epscs	epsc	NOUN
fnp-5842	68	15	)	)	PUNCT
fnp-5842	68	16	and	and	CCONJ
fnp-5842	68	17	slow	slow	VERB
fnp-5842	68	18	inward	inward	ADJ
fnp-5842	68	19	currents	current	NOUN
fnp-5842	68	20	(	(	PUNCT
fnp-5842	68	21	sics	sic	NOUN
fnp-5842	68	22	)	)	PUNCT
fnp-5842	68	23	.	.	PUNCT
fnp-5842	69	1	the	the	DET
fnp-5842	69	2	exact	exact	ADJ
fnp-5842	69	3	molecular	molecular	ADJ
fnp-5842	69	4	mechanisms	mechanism	NOUN
fnp-5842	69	5	of	of	ADP
fnp-5842	69	6	sics	sic	NOUN
fnp-5842	69	7	and	and	CCONJ
fnp-5842	69	8	their	their	PRON
fnp-5842	69	9	biological	biological	ADJ
fnp-5842	69	10	relevance	relevance	NOUN
fnp-5842	69	11	are	be	AUX
fnp-5842	69	12	incompletely	incompletely	ADV
fnp-5842	69	13	understood	understand	VERB
fnp-5842	69	14	.	.	PUNCT
fnp-5842	70	1	objective	objective	NOUN
fnp-5842	70	2	:	:	PUNCT
fnp-5842	70	3	this	this	DET
fnp-5842	70	4	project	project	NOUN
fnp-5842	70	5	addresses	address	VERB
fnp-5842	70	6	the	the	DET
fnp-5842	70	7	question	question	NOUN
fnp-5842	70	8	of	of	ADP
fnp-5842	70	9	the	the	DET
fnp-5842	70	10	biological	biological	ADJ
fnp-5842	70	11	relevance	relevance	NOUN
fnp-5842	70	12	of	of	ADP
fnp-5842	70	13	sics	sic	NOUN
fnp-5842	70	14	for	for	ADP
fnp-5842	70	15	the	the	DET
fnp-5842	70	16	growth	growth	NOUN
fnp-5842	70	17	of	of	ADP
fnp-5842	70	18	glioblastomas	glioblastoma	NOUN
fnp-5842	70	19	.	.	PUNCT
fnp-5842	71	1	materials	material	NOUN
fnp-5842	71	2	&	&	CCONJ
fnp-5842	71	3	methods	method	NOUN
fnp-5842	71	4	:	:	PUNCT
fnp-5842	71	5	patient	patient	ADJ
fnp-5842	71	6	derived	derive	VERB
fnp-5842	71	7	xenograft	xenograft	NOUN
fnp-5842	71	8	models	model	NOUN
fnp-5842	71	9	and	and	CCONJ
fnp-5842	71	10	in	in	AUX
fnp-5842	71	11	-	-	PUNCT
fnp-5842	71	12	vitro	vitro	X
fnp-5842	71	13	co	co	ADJ
fnp-5842	71	14	-	-	NOUN
fnp-5842	71	15	culture	culture	ADJ
fnp-5842	71	16	models	model	NOUN
fnp-5842	71	17	of	of	ADP
fnp-5842	71	18	neurons	neuron	NOUN
fnp-5842	71	19	and	and	CCONJ
fnp-5842	71	20	glioma	glioma	NOUN
fnp-5842	71	21	cells	cell	NOUN
fnp-5842	71	22	are	be	AUX
fnp-5842	71	23	used	use	VERB
fnp-5842	71	24	.	.	PUNCT
fnp-5842	72	1	whole	whole	ADJ
fnp-5842	72	2	cell	cell	NOUN
fnp-5842	72	3	patch	patch	ADJ
fnp-5842	72	4	-	-	PUNCT
fnp-5842	72	5	clamp	clamp	NOUN
fnp-5842	72	6	recordings	recording	NOUN
fnp-5842	72	7	of	of	ADP
fnp-5842	72	8	glioma	glioma	NOUN
fnp-5842	72	9	cells	cell	NOUN
fnp-5842	72	10	are	be	AUX
fnp-5842	72	11	performed	perform	VERB
fnp-5842	72	12	to	to	PART
fnp-5842	72	13	characterize	characterize	VERB
fnp-5842	72	14	sics	sic	NOUN
fnp-5842	72	15	.	.	PUNCT
fnp-5842	73	1	simultaneous	simultaneous	ADJ
fnp-5842	73	2	patch	patch	ADJ
fnp-5842	73	3	-	-	PUNCT
fnp-5842	73	4	clamp	clamp	NOUN
fnp-5842	73	5	recordings	recording	NOUN
fnp-5842	73	6	and	and	CCONJ
fnp-5842	73	7	calcium	calcium	NOUN
fnp-5842	73	8	imaging	imaging	NOUN
fnp-5842	73	9	are	be	AUX
fnp-5842	73	10	performed	perform	VERB
fnp-5842	73	11	to	to	PART
fnp-5842	73	12	understand	understand	VERB
fnp-5842	73	13	the	the	DET
fnp-5842	73	14	downstream	downstream	ADJ
fnp-5842	73	15	effects	effect	NOUN
fnp-5842	73	16	.	.	PUNCT
fnp-5842	74	1	results	result	NOUN
fnp-5842	74	2	:	:	PUNCT
fnp-5842	74	3	acute	acute	ADJ
fnp-5842	74	4	stimulation	stimulation	NOUN
fnp-5842	74	5	with	with	ADP
fnp-5842	74	6	glutamate	glutamate	ADJ
fnp-5842	74	7	evokes	evoke	NOUN
fnp-5842	74	8	sics	sic	NOUN
fnp-5842	74	9	in	in	ADP
fnp-5842	74	10	gbcs	gbc	NOUN
fnp-5842	74	11	from	from	ADP
fnp-5842	74	12	acute	acute	ADJ
fnp-5842	74	13	brain	brain	NOUN
fnp-5842	74	14	slices	slice	NOUN
fnp-5842	74	15	as	as	ADV
fnp-5842	74	16	well	well	ADV
fnp-5842	74	17	as	as	ADP
fnp-5842	74	18	from	from	ADP
fnp-5842	74	19	cocultures	coculture	NOUN
fnp-5842	74	20	.	.	PUNCT
fnp-5842	75	1	a	a	DET
fnp-5842	75	2	percentage	percentage	NOUN
fnp-5842	75	3	of	of	ADP
fnp-5842	75	4	the	the	DET
fnp-5842	75	5	evoked	evoked	ADJ
fnp-5842	75	6	sics	sic	NOUN
fnp-5842	75	7	are	be	AUX
fnp-5842	75	8	followed	follow	VERB
fnp-5842	75	9	by	by	ADP
fnp-5842	75	10	intracellular	intracellular	ADJ
fnp-5842	75	11	calcium	calcium	NOUN
fnp-5842	75	12	signals	signal	NOUN
fnp-5842	75	13	.	.	PUNCT
fnp-5842	76	1	the	the	DET
fnp-5842	76	2	calcium	calcium	NOUN
fnp-5842	76	3	signals	signal	NOUN
fnp-5842	76	4	are	be	AUX
fnp-5842	76	5	heterogeneous	heterogeneous	ADJ
fnp-5842	76	6	in	in	ADP
fnp-5842	76	7	size	size	NOUN
fnp-5842	76	8	and	and	CCONJ
fnp-5842	76	9	subcellular	subcellular	ADJ
fnp-5842	76	10	localization	localization	NOUN
fnp-5842	76	11	.	.	PUNCT
fnp-5842	77	1	sic	sic	ADJ
fnp-5842	77	2	-	-	PUNCT
fnp-5842	77	3	positive	positive	ADJ
fnp-5842	77	4	gbcs	gbc	NOUN
fnp-5842	77	5	exhibit	exhibit	VERB
fnp-5842	77	6	a	a	DET
fnp-5842	77	7	total	total	ADJ
fnp-5842	77	8	higher	high	ADJ
fnp-5842	77	9	growth	growth	NOUN
fnp-5842	77	10	of	of	ADP
fnp-5842	77	11	tms	tms	PROPN
fnp-5842	77	12	than	than	ADP
fnp-5842	77	13	sic	sic	ADJ
fnp-5842	77	14	-	-	PUNCT
fnp-5842	77	15	negative	negative	ADJ
fnp-5842	77	16	gbcs	gbc	NOUN
fnp-5842	77	17	.	.	PUNCT
fnp-5842	78	1	this	this	PRON
fnp-5842	78	2	is	be	AUX
fnp-5842	78	3	a	a	DET
fnp-5842	78	4	new	new	ADJ
fnp-5842	78	5	connection	connection	NOUN
fnp-5842	78	6	between	between	ADP
fnp-5842	78	7	electrical	electrical	ADJ
fnp-5842	78	8	activity	activity	NOUN
fnp-5842	78	9	and	and	CCONJ
fnp-5842	78	10	the	the	DET
fnp-5842	78	11	functional	functional	ADJ
fnp-5842	78	12	relevance	relevance	NOUN
fnp-5842	78	13	for	for	ADP
fnp-5842	78	14	glioblastoma	glioblastoma	NOUN
fnp-5842	78	15	.	.	PUNCT
fnp-5842	79	1	conclusion	conclusion	NOUN
fnp-5842	79	2	:	:	PUNCT
fnp-5842	79	3	neuronal	neuronal	ADJ
fnp-5842	79	4	input	input	NOUN
fnp-5842	79	5	of	of	ADP
fnp-5842	79	6	glutamatergic	glutamatergic	ADJ
fnp-5842	79	7	synapses	synapsis	NOUN
fnp-5842	79	8	leads	lead	VERB
fnp-5842	79	9	to	to	ADP
fnp-5842	79	10	sics	sic	NOUN
fnp-5842	79	11	and	and	CCONJ
fnp-5842	79	12	heterogeneous	heterogeneous	ADJ
fnp-5842	79	13	,	,	PUNCT
fnp-5842	79	14	intracellular	intracellular	ADJ
fnp-5842	79	15	calcium	calcium	NOUN
fnp-5842	79	16	events	event	NOUN
fnp-5842	79	17	in	in	ADP
fnp-5842	79	18	a	a	DET
fnp-5842	79	19	subset	subset	NOUN
fnp-5842	79	20	of	of	ADP
fnp-5842	79	21	gbcs	gbcs	NOUN
fnp-5842	79	22	.	.	PUNCT
fnp-5842	80	1	it	it	PRON
fnp-5842	80	2	expands	expand	VERB
fnp-5842	80	3	upon	upon	SCONJ
fnp-5842	80	4	these	these	PRON
fnp-5842	80	5	by	by	ADP
fnp-5842	80	6	showing	show	VERB
fnp-5842	80	7	a	a	DET
fnp-5842	80	8	positive	positive	ADJ
fnp-5842	80	9	correlation	correlation	NOUN
fnp-5842	80	10	between	between	ADP
fnp-5842	80	11	gbcs	gbc	NOUN
fnp-5842	80	12	with	with	ADP
fnp-5842	80	13	sics	sic	NOUN
fnp-5842	80	14	and	and	CCONJ
fnp-5842	80	15	the	the	DET
fnp-5842	80	16	growth	growth	NOUN
fnp-5842	80	17	of	of	ADP
fnp-5842	80	18	tms	tms	PROPN
fnp-5842	80	19	.	.	PUNCT
fnp-5842	81	1	targeting	target	VERB
fnp-5842	81	2	sics	sic	NOUN
fnp-5842	81	3	and	and	CCONJ
fnp-5842	81	4	subsequent	subsequent	ADJ
fnp-5842	81	5	calcium	calcium	NOUN
fnp-5842	81	6	events	event	NOUN
fnp-5842	81	7	in	in	ADP
fnp-5842	81	8	gbcs	gbc	NOUN
fnp-5842	81	9	may	may	AUX
fnp-5842	81	10	be	be	AUX
fnp-5842	81	11	a	a	DET
fnp-5842	81	12	novel	novel	ADJ
fnp-5842	81	13	therapeutic	therapeutic	ADJ
fnp-5842	81	14	approach	approach	NOUN
fnp-5842	81	15	in	in	ADP
fnp-5842	81	16	this	this	DET
fnp-5842	81	17	intractable	intractable	ADJ
fnp-5842	81	18	disease	disease	NOUN
fnp-5842	81	19	warranting	warrant	VERB
fnp-5842	81	20	further	further	ADJ
fnp-5842	81	21	investigation	investigation	NOUN
fnp-5842	81	22	.	.	PUNCT
fnp-5842	82	1	p05	p05	PROPN
fnp-5842	82	2	free	free	ADJ
fnp-5842	82	3	neuropathol	neuropathol	NOUN
fnp-5842	82	4	5:19:11	5:19:11	NUM
fnp-5842	82	5	nanopore	nanopore	ADV
fnp-5842	82	6	sequencing	sequence	VERB
fnp-5842	82	7	from	from	ADP
fnp-5842	82	8	formalin	formalin	NOUN
fnp-5842	82	9	-	-	PUNCT
fnp-5842	82	10	fixed	fix	VERB
fnp-5842	82	11	paraffin	paraffin	NOUN
fnp-5842	82	12	-	-	PUNCT
fnp-5842	82	13	embedded	embed	VERB
fnp-5842	82	14	specimens	specimen	NOUN
fnp-5842	82	15	for	for	ADP
fnp-5842	82	16	copy	copy	NOUN
fnp-5842	82	17	number	number	NOUN
fnp-5842	82	18	profiling	profiling	NOUN
fnp-5842	82	19	and	and	CCONJ
fnp-5842	82	20	methylation	methylation	NOUN
fnp-5842	82	21	-	-	PUNCT
fnp-5842	82	22	based	base	VERB
fnp-5842	82	23	cns	cns	NOUN
fnp-5842	82	24	tumor	tumor	PROPN
fnp-5842	82	25	classification	classification	PROPN
fnp-5842	82	26	ann	ann	PROPN
fnp-5842	82	27	-	-	PUNCT
fnp-5842	82	28	kristin	kristin	PROPN
fnp-5842	82	29	afflerbach1,2,3	afflerbach1,2,3	PROPN
fnp-5842	82	30	,	,	PUNCT
fnp-5842	82	31	anne	anne	PROPN
fnp-5842	82	32	albers4	albers4	PROPN
fnp-5842	82	33	,	,	PUNCT
fnp-5842	82	34	anton	anton	PROPN
fnp-5842	82	35	appelt1,2	appelt1,2	PROPN
fnp-5842	82	36	,	,	PUNCT
fnp-5842	82	37	leonille	leonille	PROPN
fnp-5842	82	38	schweizer5,6,7	schweizer5,6,7	PROPN
fnp-5842	82	39	,	,	PUNCT
fnp-5842	82	40	werner	werner	PROPN
fnp-5842	82	41	paulus4	paulus4	PROPN
fnp-5842	82	42	,	,	PUNCT
fnp-5842	82	43	michael	michael	PROPN
fnp-5842	82	44	bockmayr1,2,8	bockmayr1,2,8	PROPN
fnp-5842	82	45	,	,	PUNCT
fnp-5842	82	46	ulrich	ulrich	PROPN
fnp-5842	82	47	schüller1,2,9	schüller1,2,9	NOUN
fnp-5842	82	48	#	#	PROPN
fnp-5842	82	49	,	,	PUNCT
fnp-5842	82	50	christian	christian	ADJ
fnp-5842	82	51	thomas4	thomas4	PROPN
fnp-5842	82	52	#	#	NOUN
fnp-5842	82	53	1	1	NUM
fnp-5842	82	54	department	department	NOUN
fnp-5842	82	55	of	of	ADP
fnp-5842	82	56	pediatric	pediatric	ADJ
fnp-5842	82	57	hematology	hematology	NOUN
fnp-5842	82	58	and	and	CCONJ
fnp-5842	82	59	oncology	oncology	NOUN
fnp-5842	82	60	,	,	PUNCT
fnp-5842	82	61	university	university	NOUN
fnp-5842	82	62	medical	medical	ADJ
fnp-5842	82	63	center	center	PROPN
fnp-5842	82	64	hamburg	hamburg	PROPN
fnp-5842	82	65	-	-	PUNCT
fnp-5842	82	66	eppendorf	eppendorf	PROPN
fnp-5842	82	67	,	,	PUNCT
fnp-5842	82	68	hamburg	hamburg	PROPN
fnp-5842	82	69	,	,	PUNCT
fnp-5842	82	70	germany	germany	PROPN
fnp-5842	82	71	2	2	NUM
fnp-5842	82	72	research	research	NOUN
fnp-5842	82	73	institute	institute	NOUN
fnp-5842	82	74	children	child	NOUN
fnp-5842	82	75	’s	’s	PART
fnp-5842	82	76	cancer	cancer	NOUN
fnp-5842	82	77	center	center	PROPN
fnp-5842	82	78	hamburg	hamburg	PROPN
fnp-5842	82	79	,	,	PUNCT
fnp-5842	82	80	hamburg	hamburg	PROPN
fnp-5842	82	81	,	,	PUNCT
fnp-5842	82	82	germany	germany	PROPN
fnp-5842	82	83	3	3	PROPN
fnp-5842	82	84	institute	institute	PROPN
fnp-5842	82	85	for	for	ADP
fnp-5842	82	86	tumor	tumor	NOUN
fnp-5842	82	87	biology	biology	NOUN
fnp-5842	82	88	,	,	PUNCT
fnp-5842	82	89	university	university	NOUN
fnp-5842	82	90	medical	medical	ADJ
fnp-5842	82	91	center	center	PROPN
fnp-5842	82	92	hamburg	hamburg	PROPN
fnp-5842	82	93	-	-	PUNCT
fnp-5842	82	94	eppendorf	eppendorf	PROPN
fnp-5842	82	95	,	,	PUNCT
fnp-5842	82	96	hamburg	hamburg	PROPN
fnp-5842	82	97	,	,	PUNCT
fnp-5842	82	98	germany	germany	PROPN
fnp-5842	82	99	4	4	NUM
fnp-5842	82	100	institute	institute	PROPN
fnp-5842	82	101	of	of	ADP
fnp-5842	82	102	neuropathology	neuropathology	NOUN
fnp-5842	82	103	,	,	PUNCT
fnp-5842	82	104	university	university	NOUN
fnp-5842	82	105	hospital	hospital	NOUN
fnp-5842	82	106	münster	münster	NOUN
fnp-5842	82	107	,	,	PUNCT
fnp-5842	82	108	münster	münster	PROPN
fnp-5842	82	109	,	,	PUNCT
fnp-5842	82	110	germany	germany	PROPN
fnp-5842	82	111	5	5	NUM
fnp-5842	82	112	institute	institute	PROPN
fnp-5842	82	113	of	of	ADP
fnp-5842	82	114	neurology	neurology	NOUN
fnp-5842	82	115	(	(	PUNCT
fnp-5842	82	116	edinger	edinger	PROPN
fnp-5842	82	117	institute	institute	PROPN
fnp-5842	82	118	)	)	PUNCT
fnp-5842	82	119	,	,	PUNCT
fnp-5842	82	120	university	university	NOUN
fnp-5842	82	121	hospital	hospital	NOUN
fnp-5842	82	122	frankfurt	frankfurt	PROPN
fnp-5842	82	123	,	,	PUNCT
fnp-5842	82	124	goethe	goethe	PROPN
fnp-5842	82	125	university	university	PROPN
fnp-5842	82	126	,	,	PUNCT
fnp-5842	82	127	frankfurt	frankfurt	PROPN
fnp-5842	82	128	am	be	AUX
fnp-5842	82	129	main	main	ADJ
fnp-5842	82	130	,	,	PUNCT
fnp-5842	82	131	germany	germany	NOUN
fnp-5842	82	132	6	6	NUM
fnp-5842	82	133	german	german	ADJ
fnp-5842	82	134	cancer	cancer	NOUN
fnp-5842	82	135	consortium	consortium	NOUN
fnp-5842	82	136	(	(	PUNCT
fnp-5842	82	137	dktk	dktk	NOUN
fnp-5842	82	138	)	)	PUNCT
fnp-5842	82	139	,	,	PUNCT
fnp-5842	82	140	partner	partner	NOUN
fnp-5842	82	141	site	site	NOUN
fnp-5842	82	142	frankfurt	frankfurt	PROPN
fnp-5842	82	143	/	/	SYM
fnp-5842	82	144	mainz	mainz	PROPN
fnp-5842	82	145	,	,	PUNCT
fnp-5842	82	146	german	german	ADJ
fnp-5842	82	147	cancer	cancer	NOUN
fnp-5842	82	148	research	research	NOUN
fnp-5842	82	149	center	center	NOUN
fnp-5842	82	150	(	(	PUNCT
fnp-5842	82	151	dkfz	dkfz	PROPN
fnp-5842	82	152	)	)	PUNCT
fnp-5842	82	153	,	,	PUNCT
fnp-5842	82	154	heidelberg	heidelberg	PROPN
fnp-5842	82	155	,	,	PUNCT
fnp-5842	82	156	germany	germany	PROPN
fnp-5842	82	157	7	7	NUM
fnp-5842	82	158	frankfurt	frankfurt	PROPN
fnp-5842	82	159	cancer	cancer	PROPN
fnp-5842	82	160	institute	institute	PROPN
fnp-5842	82	161	(	(	PUNCT
fnp-5842	82	162	fci	fci	PROPN
fnp-5842	82	163	)	)	PUNCT
fnp-5842	82	164	,	,	PUNCT
fnp-5842	82	165	frankfurt	frankfurt	PROPN
fnp-5842	82	166	am	be	AUX
fnp-5842	82	167	main	main	ADJ
fnp-5842	82	168	,	,	PUNCT
fnp-5842	82	169	germany	germany	PROPN
fnp-5842	82	170	8	8	NUM
fnp-5842	82	171	baiome	baiome	PROPN
fnp-5842	82	172	center	center	NOUN
fnp-5842	82	173	for	for	ADP
fnp-5842	82	174	biomedical	biomedical	ADJ
fnp-5842	82	175	ai	ai	NOUN
fnp-5842	82	176	,	,	PUNCT
fnp-5842	82	177	university	university	NOUN
fnp-5842	82	178	medical	medical	ADJ
fnp-5842	82	179	center	center	PROPN
fnp-5842	82	180	hamburg	hamburg	PROPN
fnp-5842	82	181	-	-	PUNCT
fnp-5842	82	182	eppendorf	eppendorf	PROPN
fnp-5842	82	183	,	,	PUNCT
fnp-5842	82	184	hamburg	hamburg	PROPN
fnp-5842	82	185	,	,	PUNCT
fnp-5842	82	186	germany	germany	PROPN
fnp-5842	82	187	9	9	NUM
fnp-5842	82	188	institute	institute	PROPN
fnp-5842	82	189	of	of	ADP
fnp-5842	82	190	neuropathology	neuropathology	NOUN
fnp-5842	82	191	,	,	PUNCT
fnp-5842	82	192	university	university	NOUN
fnp-5842	82	193	medical	medical	ADJ
fnp-5842	82	194	center	center	PROPN
fnp-5842	82	195	hamburg	hamburg	PROPN
fnp-5842	82	196	-	-	PUNCT
fnp-5842	82	197	eppendorf	eppendorf	PROPN
fnp-5842	82	198	,	,	PUNCT
fnp-5842	82	199	hamburg	hamburg	PROPN
fnp-5842	82	200	,	,	PUNCT
fnp-5842	82	201	germany	germany	PROPN
fnp-5842	82	202	#	#	NOUN
fnp-5842	82	203	equal	equal	ADJ
fnp-5842	82	204	contribution	contribution	NOUN
fnp-5842	82	205	microarray	microarray	NOUN
fnp-5842	82	206	-	-	PUNCT
fnp-5842	82	207	based	base	VERB
fnp-5842	82	208	dna	dna	PROPN
fnp-5842	82	209	methylation	methylation	NOUN
fnp-5842	82	210	profiling	profiling	NOUN
fnp-5842	82	211	has	have	AUX
fnp-5842	82	212	emerged	emerge	VERB
fnp-5842	82	213	as	as	ADP
fnp-5842	82	214	a	a	DET
fnp-5842	82	215	powerful	powerful	ADJ
fnp-5842	82	216	tool	tool	NOUN
fnp-5842	82	217	for	for	ADP
fnp-5842	82	218	central	central	ADJ
fnp-5842	82	219	nervous	nervous	ADJ
fnp-5842	82	220	system	system	NOUN
fnp-5842	82	221	tumor	tumor	NOUN
fnp-5842	82	222	classification	classification	NOUN
fnp-5842	82	223	and	and	CCONJ
fnp-5842	82	224	investigation	investigation	NOUN
fnp-5842	82	225	of	of	ADP
fnp-5842	82	226	diagnostically	diagnostically	ADV
fnp-5842	82	227	relevant	relevant	ADJ
fnp-5842	82	228	copy	copy	NOUN
fnp-5842	82	229	-	-	PUNCT
fnp-5842	82	230	number	number	NOUN
fnp-5842	82	231	alterations	alteration	NOUN
fnp-5842	82	232	such	such	ADJ
fnp-5842	82	233	as	as	ADP
fnp-5842	82	234	1p/19q	1p/19q	NOUN
fnp-5842	82	235	-	-	PUNCT
fnp-5842	82	236	codeletion	codeletion	NOUN
fnp-5842	82	237	and	and	CCONJ
fnp-5842	82	238	the	the	DET
fnp-5842	82	239	+7/-10	+7/-10	PROPN
fnp-5842	82	240	signature	signature	NOUN
fnp-5842	82	241	.	.	PUNCT
fnp-5842	83	1	methylation	methylation	NOUN
fnp-5842	83	2	arrays	array	NOUN
fnp-5842	83	3	are	be	AUX
fnp-5842	83	4	well	well	ADV
fnp-5842	83	5	compatible	compatible	ADJ
fnp-5842	83	6	with	with	ADP
fnp-5842	83	7	formalin	formalin	NOUN
fnp-5842	83	8	-	-	PUNCT
fnp-5842	83	9	fixed	fix	VERB
fnp-5842	83	10	and	and	CCONJ
fnp-5842	83	11	paraffin	paraffin	NOUN
fnp-5842	83	12	-	-	PUNCT
fnp-5842	83	13	embedded	embed	VERB
fnp-5842	83	14	(	(	PUNCT
fnp-5842	83	15	ffpe	ffpe	NOUN
fnp-5842	83	16	)	)	PUNCT
fnp-5842	83	17	derived	derive	VERB
fnp-5842	83	18	dna	dna	NOUN
fnp-5842	83	19	but	but	CCONJ
fnp-5842	83	20	are	be	AUX
fnp-5842	83	21	time	time	NOUN
fnp-5842	83	22	-	-	PUNCT
fnp-5842	83	23	consuming	consume	VERB
fnp-5842	83	24	and	and	CCONJ
fnp-5842	83	25	requires	require	VERB
fnp-5842	83	26	batch	batch	NOUN
fnp-5842	83	27	processing	processing	NOUN
fnp-5842	83	28	.	.	PUNCT
fnp-5842	84	1	nanopore	nanopore	ADJ
fnp-5842	84	2	sequencing	sequencing	NOUN
fnp-5842	84	3	has	have	AUX
fnp-5842	84	4	emerged	emerge	VERB
fnp-5842	84	5	as	as	ADP
fnp-5842	84	6	a	a	DET
fnp-5842	84	7	rapid	rapid	ADJ
fnp-5842	84	8	and	and	CCONJ
fnp-5842	84	9	scalable	scalable	ADJ
fnp-5842	84	10	method	method	NOUN
fnp-5842	84	11	,	,	PUNCT
fnp-5842	84	12	enabling	enable	VERB
fnp-5842	84	13	measurement	measurement	NOUN
fnp-5842	84	14	of	of	ADP
fnp-5842	84	15	dna	dna	PROPN
fnp-5842	84	16	methylation	methylation	NOUN
fnp-5842	84	17	and	and	CCONJ
fnp-5842	84	18	generation	generation	NOUN
fnp-5842	84	19	of	of	ADP
fnp-5842	84	20	copy	copy	NOUN
fnp-5842	84	21	-	-	PUNCT
fnp-5842	84	22	number	number	NOUN
fnp-5842	84	23	profiles	profile	NOUN
fnp-5842	84	24	,	,	PUNCT
fnp-5842	84	25	but	but	CCONJ
fnp-5842	84	26	has	have	AUX
fnp-5842	84	27	been	be	AUX
fnp-5842	84	28	limited	limit	VERB
fnp-5842	84	29	to	to	ADP
fnp-5842	84	30	high	high	ADJ
fnp-5842	84	31	-	-	PUNCT
fnp-5842	84	32	quality	quality	NOUN
fnp-5842	84	33	dna	dna	NOUN
fnp-5842	84	34	from	from	ADP
fnp-5842	84	35	native	native	ADJ
fnp-5842	84	36	or	or	CCONJ
fnp-5842	84	37	cryopreserved	cryopreserved	ADJ
fnp-5842	84	38	samples	sample	NOUN
fnp-5842	84	39	so	so	ADV
fnp-5842	84	40	far	far	ADV
fnp-5842	84	41	.	.	PUNCT
fnp-5842	85	1	here	here	ADV
fnp-5842	85	2	,	,	PUNCT
fnp-5842	85	3	we	we	PRON
fnp-5842	85	4	demonstrate	demonstrate	VERB
fnp-5842	85	5	the	the	DET
fnp-5842	85	6	feasibility	feasibility	NOUN
fnp-5842	85	7	of	of	ADP
fnp-5842	85	8	nanopore	nanopore	ADJ
fnp-5842	85	9	sequencing	sequencing	NOUN
fnp-5842	85	10	from	from	ADP
fnp-5842	85	11	ffpe	ffpe	NOUN
fnp-5842	85	12	-	-	PUNCT
fnp-5842	85	13	derived	derive	VERB
fnp-5842	85	14	dna	dna	NOUN
fnp-5842	85	15	for	for	ADP
fnp-5842	85	16	methylation	methylation	NOUN
fnp-5842	85	17	-	-	PUNCT
fnp-5842	85	18	based	base	VERB
fnp-5842	85	19	classification	classification	NOUN
fnp-5842	85	20	and	and	CCONJ
fnp-5842	85	21	generation	generation	NOUN
fnp-5842	85	22	of	of	ADP
fnp-5842	85	23	genome	genome	NOUN
fnp-5842	85	24	-	-	PUNCT
fnp-5842	85	25	wide	wide	ADJ
fnp-5842	85	26	copy	copy	NOUN
fnp-5842	85	27	-	-	PUNCT
fnp-5842	85	28	number	number	NOUN
fnp-5842	85	29	profiles	profile	NOUN
fnp-5842	85	30	.	.	PUNCT
fnp-5842	86	1	ffpe	ffpe	NOUN
fnp-5842	86	2	-	-	PUNCT
fnp-5842	86	3	derived	derive	VERB
fnp-5842	86	4	dna	dna	NOUN
fnp-5842	86	5	was	be	AUX
fnp-5842	86	6	isolated	isolate	VERB
fnp-5842	86	7	from	from	ADP
fnp-5842	86	8	40	40	NUM
fnp-5842	86	9	cns	cns	NOUN
fnp-5842	86	10	tumors	tumor	NOUN
fnp-5842	86	11	(	(	PUNCT
fnp-5842	86	12	average	average	ADJ
fnp-5842	86	13	storage	storage	NOUN
fnp-5842	86	14	time	time	NOUN
fnp-5842	86	15	:	:	PUNCT
fnp-5842	86	16	19	19	NUM
fnp-5842	86	17	months	month	NOUN
fnp-5842	86	18	)	)	PUNCT
fnp-5842	86	19	including	include	VERB
fnp-5842	86	20	idh	idh	NOUN
fnp-5842	86	21	-	-	PUNCT
fnp-5842	86	22	wildtype	wildtype	NOUN
fnp-5842	86	23	glioblastomas	glioblastoma	NOUN
fnp-5842	86	24	(	(	PUNCT
fnp-5842	86	25	n	n	CCONJ
fnp-5842	86	26	 	 	SPACE
fnp-5842	86	27	=	=	NOUN
fnp-5842	86	28	 	 	SPACE
fnp-5842	86	29	8)	8)	NUM
fnp-5842	86	30	,	,	PUNCT
fnp-5842	86	31	oligodendrogliomas	oligodendroglioma	NOUN
fnp-5842	86	32	(	(	PUNCT
fnp-5842	86	33	n	n	CCONJ
fnp-5842	86	34	 	 	SPACE
fnp-5842	86	35	=	=	NOUN
fnp-5842	86	36	 	 	SPACE
fnp-5842	86	37	6	6	NUM
fnp-5842	86	38	)	)	PUNCT
fnp-5842	86	39	,	,	PUNCT
fnp-5842	86	40	posterior	posterior	ADJ
fnp-5842	86	41	fossa	fossa	ADJ
fnp-5842	86	42	ependymomas	ependymomas	PROPN
fnp-5842	86	43	(	(	PUNCT
fnp-5842	86	44	pfa	pfa	NOUN
fnp-5842	86	45	:	:	PUNCT
fnp-5842	86	46	n	n	CCONJ
fnp-5842	86	47	 	 	SPACE
fnp-5842	86	48	=	=	NOUN
fnp-5842	86	49	 	 	SPACE
fnp-5842	86	50	6	6	NUM
fnp-5842	86	51	,	,	PUNCT
fnp-5842	86	52	pfb	pfb	NOUN
fnp-5842	86	53	:	:	PUNCT
fnp-5842	86	54	n	n	CCONJ
fnp-5842	86	55	 	 	SPACE
fnp-5842	86	56	=	=	NOUN
fnp-5842	86	57	 	 	SPACE
fnp-5842	86	58	6	6	NUM
fnp-5842	86	59	)	)	PUNCT
fnp-5842	86	60	,	,	PUNCT
fnp-5842	86	61	medulloblastomas	medulloblastoma	NOUN
fnp-5842	86	62	(	(	PUNCT
fnp-5842	86	63	wnt	wnt	X
fnp-5842	86	64	:	:	PUNCT
fnp-5842	86	65	n	n	CCONJ
fnp-5842	86	66	 	 	SPACE
fnp-5842	86	67	=	=	NOUN
fnp-5842	86	68	 	 	SPACE
fnp-5842	86	69	4	4	NUM
fnp-5842	86	70	,	,	PUNCT
fnp-5842	86	71	shh	shh	NOUN
fnp-5842	86	72	:	:	PUNCT
fnp-5842	86	73	n	n	CCONJ
fnp-5842	86	74	 	 	SPACE
fnp-5842	86	75	=	=	NOUN
fnp-5842	86	76	 	 	SPACE
fnp-5842	86	77	5	5	NUM
fnp-5842	86	78	)	)	PUNCT
fnp-5842	86	79	,	,	PUNCT
fnp-5842	86	80	pilocytic	pilocytic	ADJ
fnp-5842	86	81	astrocytomas	astrocytoma	NOUN
fnp-5842	86	82	(	(	PUNCT
fnp-5842	86	83	n	n	CCONJ
fnp-5842	86	84	 	 	SPACE
fnp-5842	86	85	=	=	NOUN
fnp-5842	86	86	 	 	SPACE
fnp-5842	86	87	4	4	NUM
fnp-5842	86	88	)	)	PUNCT
fnp-5842	86	89	,	,	PUNCT
fnp-5842	86	90	and	and	CCONJ
fnp-5842	86	91	one	one	NUM
fnp-5842	86	92	meningioma	meningioma	NOUN
fnp-5842	86	93	.	.	PUNCT
fnp-5842	87	1	all	all	DET
fnp-5842	87	2	samples	sample	NOUN
fnp-5842	87	3	were	be	AUX
fnp-5842	87	4	analyzed	analyze	VERB
fnp-5842	87	5	with	with	ADP
fnp-5842	87	6	the	the	DET
fnp-5842	87	7	illumina	illumina	PROPN
fnp-5842	87	8	epic	epic	PROPN
fnp-5842	87	9	methylation	methylation	NOUN
fnp-5842	87	10	array	array	NOUN
fnp-5842	87	11	and	and	CCONJ
fnp-5842	87	12	nanopore	nanopore	ADV
fnp-5842	87	13	sequencing	sequence	VERB
fnp-5842	87	14	on	on	ADP
fnp-5842	87	15	minion	minion	NOUN
fnp-5842	87	16	devices	device	NOUN
fnp-5842	87	17	.	.	PUNCT
fnp-5842	88	1	on	on	ADP
fnp-5842	88	2	average	average	ADJ
fnp-5842	88	3	,	,	PUNCT
fnp-5842	88	4	sequencing	sequencing	NOUN
fnp-5842	88	5	runs	run	NOUN
fnp-5842	88	6	produced	produce	VERB
fnp-5842	88	7	205,000	205,000	NUM
fnp-5842	88	8	reads	read	NOUN
fnp-5842	88	9	and	and	CCONJ
fnp-5842	88	10	201	201	NUM
fnp-5842	88	11	mb	mb	NOUN
fnp-5842	88	12	per	per	ADP
fnp-5842	88	13	sample	sample	NOUN
fnp-5842	88	14	.	.	PUNCT
fnp-5842	89	1	methylation	methylation	NOUN
fnp-5842	89	2	-	-	PUNCT
fnp-5842	89	3	based	base	VERB
fnp-5842	89	4	analysis	analysis	NOUN
fnp-5842	89	5	using	use	VERB
fnp-5842	89	6	the	the	DET
fnp-5842	89	7	random	random	ADJ
fnp-5842	89	8	forest	forest	NOUN
fnp-5842	89	9	classifier	classifier	PROPN
fnp-5842	89	10	nanodx	nanodx	PROPN
fnp-5842	89	11	resulted	result	VERB
fnp-5842	89	12	in	in	ADP
fnp-5842	89	13	correct	correct	ADJ
fnp-5842	89	14	classification	classification	NOUN
fnp-5842	89	15	in	in	ADP
fnp-5842	89	16	25/40	25/40	NUM
fnp-5842	89	17	samples	sample	NOUN
fnp-5842	89	18	(	(	PUNCT
fnp-5842	89	19	63	63	NUM
fnp-5842	89	20	 	 	SPACE
fnp-5842	89	21	%	%	NOUN
fnp-5842	89	22	)	)	PUNCT
fnp-5842	89	23	,	,	PUNCT
fnp-5842	89	24	whereas	whereas	SCONJ
fnp-5842	89	25	sturgeon	sturgeon	NOUN
fnp-5842	89	26	classified	classify	VERB
fnp-5842	89	27	the	the	DET
fnp-5842	89	28	vast	vast	ADJ
fnp-5842	89	29	majority	majority	NOUN
fnp-5842	89	30	of	of	ADP
fnp-5842	89	31	samples	sample	NOUN
fnp-5842	89	32	correctly	correctly	ADV
fnp-5842	89	33	(	(	PUNCT
fnp-5842	89	34	37/40	37/40	NUM
fnp-5842	89	35	,	,	PUNCT
fnp-5842	89	36	93	93	NUM
fnp-5842	89	37	 	 	SPACE
fnp-5842	89	38	%	%	NOUN
fnp-5842	89	39	)	)	PUNCT
fnp-5842	89	40	,	,	PUNCT
fnp-5842	89	41	including	include	VERB
fnp-5842	89	42	14/16	14/16	NUM
fnp-5842	89	43	samples	sample	NOUN
fnp-5842	89	44	with	with	ADP
fnp-5842	89	45	poor	poor	ADJ
fnp-5842	89	46	dna	dna	NOUN
fnp-5842	89	47	quality	quality	NOUN
fnp-5842	89	48	(	(	PUNCT
fnp-5842	89	49	din	din	VERB
fnp-5842	89	50	 	 	SPACE
fnp-5842	89	51	<	<	NOUN
fnp-5842	89	52	 	 	SPACE
fnp-5842	89	53	5	5	NUM
fnp-5842	89	54	)	)	PUNCT
fnp-5842	89	55	.	.	PUNCT
fnp-5842	90	1	all	all	DET
fnp-5842	90	2	idh	idh	NOUN
fnp-5842	90	3	-	-	PUNCT
fnp-5842	90	4	wildtype	wildtype	NOUN
fnp-5842	90	5	glioblastomas	glioblastoma	NOUN
fnp-5842	90	6	showed	show	VERB
fnp-5842	90	7	the	the	DET
fnp-5842	90	8	+7/-10	+7/-10	PROPN
fnp-5842	90	9	signature	signature	NOUN
fnp-5842	90	10	,	,	PUNCT
fnp-5842	90	11	and	and	CCONJ
fnp-5842	90	12	all	all	DET
fnp-5842	90	13	oligodendrogliomas	oligodendroglioma	NOUN
fnp-5842	90	14	harbored	harbor	VERB
fnp-5842	90	15	a	a	DET
fnp-5842	90	16	1p/19q	1p/19q	NOUN
fnp-5842	90	17	-	-	PUNCT
fnp-5842	90	18	codeletion	codeletion	NOUN
fnp-5842	90	19	.	.	PUNCT
fnp-5842	91	1	taken	take	VERB
fnp-5842	91	2	together	together	ADV
fnp-5842	91	3	,	,	PUNCT
fnp-5842	91	4	our	our	PRON
fnp-5842	91	5	study	study	NOUN
fnp-5842	91	6	demonstrates	demonstrate	VERB
fnp-5842	91	7	the	the	DET
fnp-5842	91	8	feasibility	feasibility	NOUN
fnp-5842	91	9	of	of	ADP
fnp-5842	91	10	rapid	rapid	ADJ
fnp-5842	91	11	methylation	methylation	NOUN
fnp-5842	91	12	profiling	profiling	NOUN
fnp-5842	91	13	and	and	CCONJ
fnp-5842	91	14	copy	copy	NOUN
fnp-5842	91	15	-	-	PUNCT
fnp-5842	91	16	number	number	NOUN
fnp-5842	91	17	analysis	analysis	NOUN
fnp-5842	91	18	of	of	ADP
fnp-5842	91	19	ffpe	ffpe	NOUN
fnp-5842	91	20	specimens	specimen	NOUN
fnp-5842	91	21	using	use	VERB
fnp-5842	91	22	nanopore	nanopore	ADJ
fnp-5842	91	23	sequencing	sequencing	NOUN
fnp-5842	91	24	.	.	PUNCT
fnp-5842	92	1	sturgeon	sturgeon	NOUN
fnp-5842	92	2	,	,	PUNCT
fnp-5842	92	3	a	a	DET
fnp-5842	92	4	neural	neural	ADJ
fnp-5842	92	5	network	network	NOUN
fnp-5842	92	6	-	-	PUNCT
fnp-5842	92	7	based	base	VERB
fnp-5842	92	8	classifier	classifier	NOUN
fnp-5842	92	9	,	,	PUNCT
fnp-5842	92	10	performed	perform	VERB
fnp-5842	92	11	considerably	considerably	ADV
fnp-5842	92	12	better	well	ADJ
fnp-5842	92	13	than	than	ADP
fnp-5842	92	14	the	the	DET
fnp-5842	92	15	random	random	ADJ
fnp-5842	92	16	forest	forest	NOUN
fnp-5842	92	17	-	-	PUNCT
fnp-5842	92	18	based	base	VERB
fnp-5842	92	19	classifier	classifier	PROPN
fnp-5842	92	20	nanodx	nanodx	PROPN
fnp-5842	92	21	.	.	PUNCT
fnp-5842	93	1	p06	p06	VERB
fnp-5842	93	2	free	free	ADJ
fnp-5842	93	3	neuropathol	neuropathol	NOUN
fnp-5842	93	4	5:19:13	5:19:13	NUM
fnp-5842	93	5	epigenetic	epigenetic	ADJ
fnp-5842	93	6	profiling	profiling	NOUN
fnp-5842	93	7	can	can	AUX
fnp-5842	93	8	improve	improve	VERB
fnp-5842	93	9	diagnostics	diagnostic	NOUN
fnp-5842	93	10	of	of	ADP
fnp-5842	93	11	mpnst	mpnst	NOUN
fnp-5842	93	12	with	with	ADP
fnp-5842	93	13	intratumoral	intratumoral	ADJ
fnp-5842	93	14	histological	histological	ADJ
fnp-5842	93	15	heterogeneity	heterogeneity	NOUN
fnp-5842	93	16	tomas	toma	NOUN
fnp-5842	93	17	phan1	phan1	ADV
fnp-5842	93	18	,	,	PUNCT
fnp-5842	93	19	karoline	karoline	PROPN
fnp-5842	93	20	hack1,2	hack1,2	PROPN
fnp-5842	93	21	,	,	PUNCT
fnp-5842	93	22	lennart	lennart	PROPN
fnp-5842	93	23	well3,4	well3,4	PROPN
fnp-5842	93	24	,	,	PUNCT
fnp-5842	93	25	inka	inka	PROPN
fnp-5842	93	26	ristow3,4	ristow3,4	PROPN
fnp-5842	93	27	,	,	PUNCT
fnp-5842	93	28	lan	lan	PROPN
fnp-5842	93	29	kluwe5	kluwe5	PROPN
fnp-5842	93	30	,	,	PUNCT
fnp-5842	93	31	said	say	VERB
fnp-5842	93	32	farschtschi5	farschtschi5	NOUN
fnp-5842	93	33	,	,	PUNCT
fnp-5842	93	34	markus	markus	PROPN
fnp-5842	93	35	glatzel6	glatzel6	PROPN
fnp-5842	93	36	,	,	PUNCT
fnp-5842	93	37	victor	victor	PROPN
fnp-5842	93	38	-	-	PUNCT
fnp-5842	93	39	felix	felix	PROPN
fnp-5842	93	40	mautner5	mautner5	PROPN
fnp-5842	93	41	,	,	PUNCT
fnp-5842	93	42	ulrich	ulrich	PROPN
fnp-5842	93	43	schüller1,7	schüller1,7	PROPN
fnp-5842	93	44	,	,	PUNCT
fnp-5842	93	45	catena	catena	PROPN
fnp-5842	93	46	kresbach1,2,6,7	kresbach1,2,6,7	PROPN
fnp-5842	93	47	1	1	NUM
fnp-5842	93	48	research	research	PROPN
fnp-5842	93	49	institute	institute	NOUN
fnp-5842	93	50	children	child	NOUN
fnp-5842	93	51	's	's	PART
fnp-5842	93	52	cancer	cancer	NOUN
fnp-5842	93	53	center	center	NOUN
fnp-5842	93	54	,	,	PUNCT
fnp-5842	93	55	hamburg	hamburg	PROPN
fnp-5842	93	56	,	,	PUNCT
fnp-5842	93	57	germany	germany	PROPN
fnp-5842	93	58	2	2	NUM
fnp-5842	93	59	department	department	NOUN
fnp-5842	93	60	of	of	ADP
fnp-5842	93	61	pediatric	pediatric	ADJ
fnp-5842	93	62	hematology	hematology	NOUN
fnp-5842	93	63	and	and	CCONJ
fnp-5842	93	64	oncology	oncology	NOUN
fnp-5842	93	65	,	,	PUNCT
fnp-5842	93	66	university	university	NOUN
fnp-5842	93	67	medical	medical	ADJ
fnp-5842	93	68	center	center	PROPN
fnp-5842	93	69	hamburg	hamburg	PROPN
fnp-5842	93	70	-	-	PUNCT
fnp-5842	93	71	eppendorf	eppendorf	PROPN
fnp-5842	93	72	,	,	PUNCT
fnp-5842	93	73	hamburg	hamburg	PROPN
fnp-5842	93	74	,	,	PUNCT
fnp-5842	93	75	germany	germany	PROPN
fnp-5842	93	76	3	3	NUM
fnp-5842	93	77	lab	lab	NOUN
fnp-5842	93	78	of	of	ADP
fnp-5842	93	79	radiobiology	radiobiology	NOUN
fnp-5842	93	80	&	&	CCONJ
fnp-5842	93	81	experimental	experimental	ADJ
fnp-5842	93	82	radiation	radiation	NOUN
fnp-5842	93	83	oncology	oncology	NOUN
fnp-5842	93	84	,	,	PUNCT
fnp-5842	93	85	hubertus	hubertus	PROPN
fnp-5842	93	86	wald	wald	PROPN
fnp-5842	93	87	tumorzentrum	tumorzentrum	PROPN
fnp-5842	93	88	,	,	PUNCT
fnp-5842	93	89	university	university	NOUN
fnp-5842	93	90	cancer	cancer	NOUN
fnp-5842	93	91	center	center	PROPN
fnp-5842	93	92	hamburg	hamburg	PROPN
fnp-5842	93	93	,	,	PUNCT
fnp-5842	93	94	university	university	NOUN
fnp-5842	93	95	medical	medical	ADJ
fnp-5842	93	96	center	center	PROPN
fnp-5842	93	97	hamburg	hamburg	PROPN
fnp-5842	93	98	-	-	PUNCT
fnp-5842	93	99	eppendorf	eppendorf	PROPN
fnp-5842	93	100	,	,	PUNCT
fnp-5842	93	101	hamburg	hamburg	PROPN
fnp-5842	93	102	,	,	PUNCT
fnp-5842	93	103	germany	germany	PROPN
fnp-5842	93	104	4	4	NUM
fnp-5842	93	105	department	department	NOUN
fnp-5842	93	106	of	of	ADP
fnp-5842	93	107	diagnostic	diagnostic	ADJ
fnp-5842	93	108	and	and	CCONJ
fnp-5842	93	109	interventional	interventional	ADJ
fnp-5842	93	110	radiology	radiology	NOUN
fnp-5842	93	111	and	and	CCONJ
fnp-5842	93	112	nuclear	nuclear	ADJ
fnp-5842	93	113	medicine	medicine	NOUN
fnp-5842	93	114	,	,	PUNCT
fnp-5842	93	115	university	university	NOUN
fnp-5842	93	116	medical	medical	ADJ
fnp-5842	93	117	center	center	PROPN
fnp-5842	93	118	hamburg	hamburg	PROPN
fnp-5842	93	119	-	-	PUNCT
fnp-5842	93	120	eppendorf	eppendorf	PROPN
fnp-5842	93	121	,	,	PUNCT
fnp-5842	93	122	hamburg	hamburg	PROPN
fnp-5842	93	123	,	,	PUNCT
fnp-5842	93	124	germany	germany	PROPN
fnp-5842	93	125	5	5	NUM
fnp-5842	93	126	department	department	PROPN
fnp-5842	93	127	of	of	ADP
fnp-5842	93	128	neurology	neurology	NOUN
fnp-5842	93	129	,	,	PUNCT
fnp-5842	93	130	university	university	NOUN
fnp-5842	93	131	medical	medical	ADJ
fnp-5842	93	132	center	center	PROPN
fnp-5842	93	133	hamburg	hamburg	PROPN
fnp-5842	93	134	-	-	PUNCT
fnp-5842	93	135	eppendorf	eppendorf	PROPN
fnp-5842	93	136	,	,	PUNCT
fnp-5842	93	137	hamburg	hamburg	PROPN
fnp-5842	93	138	,	,	PUNCT
fnp-5842	93	139	germany	germany	PROPN
fnp-5842	93	140	6	6	NUM
fnp-5842	93	141	department	department	NOUN
fnp-5842	93	142	of	of	ADP
fnp-5842	93	143	diagnostics	diagnostic	NOUN
fnp-5842	93	144	,	,	PUNCT
fnp-5842	93	145	institute	institute	NOUN
fnp-5842	93	146	of	of	ADP
fnp-5842	93	147	neuropathology	neuropathology	NOUN
fnp-5842	93	148	,	,	PUNCT
fnp-5842	93	149	university	university	NOUN
fnp-5842	93	150	medical	medical	ADJ
fnp-5842	93	151	center	center	PROPN
fnp-5842	93	152	hamburg	hamburg	PROPN
fnp-5842	93	153	-	-	PUNCT
fnp-5842	93	154	eppendorf	eppendorf	PROPN
fnp-5842	93	155	,	,	PUNCT
fnp-5842	93	156	germany	germany	PROPN
fnp-5842	93	157	7	7	NUM
fnp-5842	93	158	mildred	mildred	PROPN
fnp-5842	93	159	scheel	scheel	PROPN
fnp-5842	93	160	cancer	cancer	NOUN
fnp-5842	93	161	career	career	NOUN
fnp-5842	93	162	center	center	NOUN
fnp-5842	93	163	hatrics4	hatrics4	NOUN
fnp-5842	93	164	,	,	PUNCT
fnp-5842	93	165	university	university	NOUN
fnp-5842	93	166	medical	medical	ADJ
fnp-5842	93	167	center	center	NOUN
fnp-5842	93	168	hamburgeppendorf	hamburgeppendorf	PROPN
fnp-5842	93	169	,	,	PUNCT
fnp-5842	93	170	hamburg	hamburg	PROPN
fnp-5842	93	171	,	,	PUNCT
fnp-5842	93	172	germany	germany	PROPN
fnp-5842	93	173	introduction	introduction	NOUN
fnp-5842	93	174	:	:	PUNCT
fnp-5842	93	175	approximately	approximately	ADV
fnp-5842	93	176	10	10	NUM
fnp-5842	93	177	 	 	SPACE
fnp-5842	93	178	%	%	NOUN
fnp-5842	93	179	of	of	ADP
fnp-5842	93	180	nf1	nf1	NOUN
fnp-5842	93	181	patients	patient	NOUN
fnp-5842	93	182	develop	develop	VERB
fnp-5842	93	183	malignant	malignant	ADJ
fnp-5842	93	184	peripheral	peripheral	ADJ
fnp-5842	93	185	nerve	nerve	NOUN
fnp-5842	93	186	sheath	sheath	NOUN
fnp-5842	93	187	tumors	tumor	NOUN
fnp-5842	93	188	(	(	PUNCT
fnp-5842	93	189	mpnst	mpnst	NOUN
fnp-5842	93	190	)	)	PUNCT
fnp-5842	93	191	with	with	ADP
fnp-5842	93	192	a	a	DET
fnp-5842	93	193	poor	poor	ADJ
fnp-5842	93	194	prognosis	prognosis	NOUN
fnp-5842	93	195	,	,	PUNCT
fnp-5842	93	196	making	make	VERB
fnp-5842	93	197	early	early	ADJ
fnp-5842	93	198	detection	detection	NOUN
fnp-5842	93	199	crucial	crucial	ADJ
fnp-5842	93	200	.	.	PUNCT
fnp-5842	94	1	mpnst	mpnst	NOUN
fnp-5842	94	2	exhibit	exhibit	PROPN
fnp-5842	94	3	pronounced	pronounce	VERB
fnp-5842	94	4	intratumoral	intratumoral	ADJ
fnp-5842	94	5	heterogeneity	heterogeneity	NOUN
fnp-5842	94	6	,	,	PUNCT
fnp-5842	94	7	often	often	ADV
fnp-5842	94	8	containing	contain	VERB
fnp-5842	94	9	areas	area	NOUN
fnp-5842	94	10	resembling	resemble	VERB
fnp-5842	94	11	plexiform	plexiform	NOUN
fnp-5842	94	12	neurofibroma	neurofibroma	NOUN
fnp-5842	94	13	(	(	PUNCT
fnp-5842	94	14	pnf	pnf	PROPN
fnp-5842	94	15	)	)	PUNCT
fnp-5842	94	16	,	,	PUNCT
fnp-5842	94	17	atypical	atypical	ADJ
fnp-5842	94	18	neurofibroma	neurofibroma	NOUN
fnp-5842	94	19	(	(	PUNCT
fnp-5842	94	20	annubp	annubp	ADJ
fnp-5842	94	21	)	)	PUNCT
fnp-5842	94	22	,	,	PUNCT
fnp-5842	94	23	and	and	CCONJ
fnp-5842	94	24	mpnst	mpnst	NOUN
fnp-5842	94	25	.	.	PUNCT
fnp-5842	95	1	consequently	consequently	ADV
fnp-5842	95	2	,	,	PUNCT
fnp-5842	95	3	ct	ct	NOUN
fnp-5842	95	4	-	-	PUNCT
fnp-5842	95	5	guided	guide	VERB
fnp-5842	95	6	biopsies	biopsy	NOUN
fnp-5842	95	7	may	may	AUX
fnp-5842	95	8	miss	miss	VERB
fnp-5842	95	9	critical	critical	ADJ
fnp-5842	95	10	tumor	tumor	NOUN
fnp-5842	95	11	features	feature	NOUN
fnp-5842	95	12	.	.	PUNCT
fnp-5842	96	1	this	this	DET
fnp-5842	96	2	study	study	NOUN
fnp-5842	96	3	aims	aim	VERB
fnp-5842	96	4	to	to	PART
fnp-5842	96	5	delineate	delineate	VERB
fnp-5842	96	6	mpnst	mpnst	NOUN
fnp-5842	96	7	heterogeneity	heterogeneity	NOUN
fnp-5842	96	8	histologically	histologically	ADV
fnp-5842	96	9	and	and	CCONJ
fnp-5842	96	10	molecularly	molecularly	ADV
fnp-5842	96	11	to	to	PART
fnp-5842	96	12	improve	improve	VERB
fnp-5842	96	13	diagnostic	diagnostic	ADJ
fnp-5842	96	14	precision	precision	NOUN
fnp-5842	96	15	and	and	CCONJ
fnp-5842	96	16	to	to	PART
fnp-5842	96	17	better	well	ADV
fnp-5842	96	18	understand	understand	VERB
fnp-5842	96	19	the	the	DET
fnp-5842	96	20	mechanisms	mechanism	NOUN
fnp-5842	96	21	of	of	ADP
fnp-5842	96	22	malignant	malignant	ADJ
fnp-5842	96	23	progression	progression	NOUN
fnp-5842	96	24	.	.	PUNCT
fnp-5842	97	1	methods	method	NOUN
fnp-5842	97	2	:	:	PUNCT
fnp-5842	97	3	evaluation	evaluation	NOUN
fnp-5842	97	4	of	of	ADP
fnp-5842	97	5	tissue	tissue	NOUN
fnp-5842	97	6	morphology	morphology	NOUN
fnp-5842	97	7	on	on	ADP
fnp-5842	97	8	h&e	h&e	PROPN
fnp-5842	97	9	-	-	PUNCT
fnp-5842	97	10	stained	stain	VERB
fnp-5842	97	11	sections	section	NOUN
fnp-5842	97	12	,	,	PUNCT
fnp-5842	97	13	immunohistochemistry	immunohistochemistry	NOUN
fnp-5842	97	14	,	,	PUNCT
fnp-5842	97	15	global	global	ADJ
fnp-5842	97	16	methylation	methylation	NOUN
fnp-5842	97	17	profiling	profiling	NOUN
fnp-5842	97	18	(	(	PUNCT
fnp-5842	97	19	850k	850k	PROPN
fnp-5842	97	20	illumina	illumina	PROPN
fnp-5842	97	21	epic	epic	PROPN
fnp-5842	97	22	arrays	array	NOUN
fnp-5842	97	23	)	)	PUNCT
fnp-5842	97	24	,	,	PUNCT
fnp-5842	97	25	and	and	CCONJ
fnp-5842	97	26	gene	gene	NOUN
fnp-5842	97	27	sequencing	sequence	VERB
fnp-5842	97	28	panels	panel	NOUN
fnp-5842	97	29	.	.	PUNCT
fnp-5842	98	1	results	result	NOUN
fnp-5842	98	2	:	:	PUNCT
fnp-5842	98	3	we	we	PRON
fnp-5842	98	4	chose	choose	VERB
fnp-5842	98	5	one	one	NUM
fnp-5842	98	6	area	area	NOUN
fnp-5842	98	7	with	with	ADP
fnp-5842	98	8	premalignant	premalignant	NOUN
fnp-5842	98	9	and	and	CCONJ
fnp-5842	98	10	one	one	NUM
fnp-5842	98	11	area	area	NOUN
fnp-5842	98	12	with	with	ADP
fnp-5842	98	13	mpnst	mpnst	NOUN
fnp-5842	98	14	morphology	morphology	NOUN
fnp-5842	98	15	per	per	ADP
fnp-5842	98	16	tumor	tumor	NOUN
fnp-5842	98	17	for	for	ADP
fnp-5842	98	18	molecular	molecular	ADJ
fnp-5842	98	19	analysis	analysis	NOUN
fnp-5842	98	20	.	.	PUNCT
fnp-5842	99	1	clustering	cluster	VERB
fnp-5842	99	2	analysis	analysis	NOUN
fnp-5842	99	3	showed	show	VERB
fnp-5842	99	4	similar	similar	ADJ
fnp-5842	99	5	epigenetic	epigenetic	ADJ
fnp-5842	99	6	characteristics	characteristic	NOUN
fnp-5842	99	7	in	in	ADP
fnp-5842	99	8	both	both	DET
fnp-5842	99	9	areas	area	NOUN
fnp-5842	99	10	in	in	ADP
fnp-5842	99	11	5/10	5/10	NUM
fnp-5842	99	12	cases	case	NOUN
fnp-5842	99	13	.	.	PUNCT
fnp-5842	100	1	the	the	DET
fnp-5842	100	2	remaining	remain	VERB
fnp-5842	100	3	5	5	NUM
fnp-5842	100	4	cases	case	NOUN
fnp-5842	100	5	displayed	display	VERB
fnp-5842	100	6	distinct	distinct	ADJ
fnp-5842	100	7	epigenetic	epigenetic	ADJ
fnp-5842	100	8	profiles	profile	NOUN
fnp-5842	100	9	,	,	PUNCT
fnp-5842	100	10	with	with	ADP
fnp-5842	100	11	premalignant	premalignant	ADJ
fnp-5842	100	12	areas	area	NOUN
fnp-5842	100	13	clustering	cluster	VERB
fnp-5842	100	14	with	with	ADP
fnp-5842	100	15	annubp	annubp	ADJ
fnp-5842	100	16	and	and	CCONJ
fnp-5842	100	17	malignant	malignant	ADJ
fnp-5842	100	18	areas	area	NOUN
fnp-5842	100	19	clustering	cluster	VERB
fnp-5842	100	20	with	with	ADP
fnp-5842	100	21	mpnst	mpnst	NOUN
fnp-5842	100	22	.	.	PUNCT
fnp-5842	101	1	copy	copy	NOUN
fnp-5842	101	2	number	number	NOUN
fnp-5842	101	3	profiles	profile	NOUN
fnp-5842	101	4	showed	show	VERB
fnp-5842	101	5	marked	mark	VERB
fnp-5842	101	6	alterations	alteration	NOUN
fnp-5842	101	7	not	not	PART
fnp-5842	101	8	only	only	ADV
fnp-5842	101	9	in	in	ADP
fnp-5842	101	10	the	the	DET
fnp-5842	101	11	high	high	ADJ
fnp-5842	101	12	-	-	PUNCT
fnp-5842	101	13	grade	grade	NOUN
fnp-5842	101	14	areas	area	NOUN
fnp-5842	101	15	but	but	CCONJ
fnp-5842	101	16	also	also	ADV
fnp-5842	101	17	in	in	ADP
fnp-5842	101	18	the	the	DET
fnp-5842	101	19	histologically	histologically	ADV
fnp-5842	101	20	benign	benign	ADJ
fnp-5842	101	21	areas	area	NOUN
fnp-5842	101	22	in	in	ADP
fnp-5842	101	23	8/10	8/10	NUM
fnp-5842	101	24	cases	case	NOUN
fnp-5842	101	25	.	.	PUNCT
fnp-5842	102	1	gene	gene	NOUN
fnp-5842	102	2	sequencing	sequence	VERB
fnp-5842	102	3	identified	identify	VERB
fnp-5842	102	4	identical	identical	ADJ
fnp-5842	102	5	mutations	mutation	NOUN
fnp-5842	102	6	in	in	ADP
fnp-5842	102	7	suz12	suz12	NOUN
fnp-5842	102	8	and	and	CCONJ
fnp-5842	102	9	tp53	tp53	PROPN
fnp-5842	102	10	in	in	ADP
fnp-5842	102	11	premalignant	premalignant	ADJ
fnp-5842	102	12	and	and	CCONJ
fnp-5842	102	13	malignant	malignant	ADJ
fnp-5842	102	14	areas	area	NOUN
fnp-5842	102	15	in	in	ADP
fnp-5842	102	16	2/10	2/10	NUM
fnp-5842	102	17	cases	case	NOUN
fnp-5842	102	18	,	,	PUNCT
fnp-5842	102	19	and	and	CCONJ
fnp-5842	102	20	mpnst	mpnst	NOUN
fnp-5842	102	21	-	-	PUNCT
fnp-5842	102	22	typical	typical	ADJ
fnp-5842	102	23	mutations	mutation	NOUN
fnp-5842	102	24	in	in	ADP
fnp-5842	102	25	tp53	tp53	PROPN
fnp-5842	102	26	and	and	CCONJ
fnp-5842	102	27	eed	ee	VERB
fnp-5842	102	28	observed	observe	VERB
fnp-5842	102	29	exclusively	exclusively	ADV
fnp-5842	102	30	in	in	ADP
fnp-5842	102	31	high	high	ADJ
fnp-5842	102	32	-	-	PUNCT
fnp-5842	102	33	grade	grade	NOUN
fnp-5842	102	34	areas	area	NOUN
fnp-5842	102	35	in	in	ADP
fnp-5842	102	36	3/10	3/10	NUM
fnp-5842	102	37	cases	case	NOUN
fnp-5842	102	38	.	.	PUNCT
fnp-5842	103	1	conclusions	conclusion	NOUN
fnp-5842	103	2	:	:	PUNCT
fnp-5842	103	3	our	our	PRON
fnp-5842	103	4	findings	finding	NOUN
fnp-5842	103	5	highlight	highlight	VERB
fnp-5842	103	6	that	that	SCONJ
fnp-5842	103	7	the	the	DET
fnp-5842	103	8	histology	histology	NOUN
fnp-5842	103	9	of	of	ADP
fnp-5842	103	10	mpnst	mpnst	NOUN
fnp-5842	103	11	biopsies	biopsy	NOUN
fnp-5842	103	12	may	may	AUX
fnp-5842	103	13	often	often	ADV
fnp-5842	103	14	not	not	PART
fnp-5842	103	15	fully	fully	ADV
fnp-5842	103	16	represent	represent	VERB
fnp-5842	103	17	the	the	DET
fnp-5842	103	18	underlying	underlie	VERB
fnp-5842	103	19	tumor	tumor	NOUN
fnp-5842	103	20	biology	biology	NOUN
fnp-5842	103	21	.	.	PUNCT
fnp-5842	104	1	we	we	PRON
fnp-5842	104	2	show	show	VERB
fnp-5842	104	3	that	that	SCONJ
fnp-5842	104	4	genetic	genetic	ADJ
fnp-5842	104	5	and	and	CCONJ
fnp-5842	104	6	epigenetic	epigenetic	ADJ
fnp-5842	104	7	changes	change	NOUN
fnp-5842	104	8	occur	occur	VERB
fnp-5842	104	9	before	before	SCONJ
fnp-5842	104	10	histological	histological	ADJ
fnp-5842	104	11	features	feature	NOUN
fnp-5842	104	12	of	of	ADP
fnp-5842	104	13	malignancy	malignancy	NOUN
fnp-5842	104	14	become	become	VERB
fnp-5842	104	15	apparent	apparent	ADJ
fnp-5842	104	16	.	.	PUNCT
fnp-5842	105	1	this	this	DET
fnp-5842	105	2	study	study	NOUN
fnp-5842	105	3	underscores	underscore	VERB
fnp-5842	105	4	the	the	DET
fnp-5842	105	5	diagnostic	diagnostic	ADJ
fnp-5842	105	6	relevance	relevance	NOUN
fnp-5842	105	7	of	of	ADP
fnp-5842	105	8	mpnst	mpnst	PROPN
fnp-5842	105	9	intratumoral	intratumoral	ADJ
fnp-5842	105	10	heterogeneity	heterogeneity	NOUN
fnp-5842	105	11	and	and	CCONJ
fnp-5842	105	12	the	the	DET
fnp-5842	105	13	need	need	NOUN
fnp-5842	105	14	for	for	ADP
fnp-5842	105	15	comprehensive	comprehensive	ADJ
fnp-5842	105	16	diagnostic	diagnostic	ADJ
fnp-5842	105	17	approaches	approach	NOUN
fnp-5842	105	18	especially	especially	ADV
fnp-5842	105	19	in	in	ADP
fnp-5842	105	20	needle	needle	NOUN
fnp-5842	105	21	biopsies	biopsy	NOUN
fnp-5842	105	22	.	.	PUNCT
fnp-5842	106	1	p07	p07	PROPN
fnp-5842	106	2	free	free	ADJ
fnp-5842	106	3	neuropathol	neuropathol	NOUN
fnp-5842	106	4	5:19:15	5:19:15	NUM
fnp-5842	106	5	anaplastic	anaplastic	ADJ
fnp-5842	106	6	histology	histology	NOUN
fnp-5842	106	7	and	and	CCONJ
fnp-5842	106	8	distinct	distinct	ADJ
fnp-5842	106	9	molecular	molecular	ADJ
fnp-5842	106	10	features	feature	NOUN
fnp-5842	106	11	in	in	ADP
fnp-5842	106	12	a	a	DET
fnp-5842	106	13	small	small	ADJ
fnp-5842	106	14	series	series	NOUN
fnp-5842	106	15	of	of	ADP
fnp-5842	106	16	spinal	spinal	PROPN
fnp-5842	106	17	cord	cord	NOUN
fnp-5842	106	18	ependymomas	ependymomas	PROPN
fnp-5842	106	19	ulrich	ulrich	PROPN
fnp-5842	106	20	schüller1,2,3	schüller1,2,3	PROPN
fnp-5842	106	21	,	,	PUNCT
fnp-5842	106	22	*	*	PROPN
fnp-5842	106	23	,	,	PUNCT
fnp-5842	106	24	antonia	antonia	PROPN
fnp-5842	106	25	gocke4,5	gocke4,5	PROPN
fnp-5842	106	26	,	,	PUNCT
fnp-5842	106	27	*	*	PROPN
fnp-5842	106	28	,	,	PUNCT
fnp-5842	106	29	karoline	karoline	PROPN
fnp-5842	106	30	hack1,2	hack1,2	PROPN
fnp-5842	106	31	,	,	PUNCT
fnp-5842	106	32	shweta	shweta	PROPN
fnp-5842	106	33	godbole4	godbole4	PROPN
fnp-5842	106	34	,	,	PUNCT
fnp-5842	106	35	claire	claire	PROPN
fnp-5842	106	36	delbridge6	delbridge6	PROPN
fnp-5842	106	37	,	,	PUNCT
fnp-5842	106	38	christian	christian	PROPN
fnp-5842	106	39	thomas7	thomas7	PROPN
fnp-5842	106	40	,	,	PUNCT
fnp-5842	106	41	julia	julia	PROPN
fnp-5842	106	42	e.	e.	PROPN
fnp-5842	106	43	neumann3,4	neumann3,4	PROPN
fnp-5842	106	44	1	1	NUM
fnp-5842	106	45	department	department	NOUN
fnp-5842	106	46	of	of	ADP
fnp-5842	106	47	pediatric	pediatric	ADJ
fnp-5842	106	48	hematology	hematology	NOUN
fnp-5842	106	49	and	and	CCONJ
fnp-5842	106	50	oncology	oncology	NOUN
fnp-5842	106	51	,	,	PUNCT
fnp-5842	106	52	university	university	NOUN
fnp-5842	106	53	medical	medical	ADJ
fnp-5842	106	54	center	center	PROPN
fnp-5842	106	55	hamburg	hamburg	PROPN
fnp-5842	106	56	-	-	PUNCT
fnp-5842	106	57	eppendorf	eppendorf	PROPN
fnp-5842	106	58	,	,	PUNCT
fnp-5842	106	59	hamburg	hamburg	PROPN
fnp-5842	106	60	,	,	PUNCT
fnp-5842	106	61	germany	germany	PROPN
fnp-5842	106	62	2	2	NUM
fnp-5842	106	63	research	research	NOUN
fnp-5842	106	64	institute	institute	NOUN
fnp-5842	106	65	children	child	NOUN
fnp-5842	106	66	's	's	PART
fnp-5842	106	67	cancer	cancer	NOUN
fnp-5842	106	68	center	center	NOUN
fnp-5842	106	69	hamburg	hamburg	PROPN
fnp-5842	106	70	,	,	PUNCT
fnp-5842	106	71	hamburg	hamburg	PROPN
fnp-5842	106	72	,	,	PUNCT
fnp-5842	106	73	germany	germany	PROPN
fnp-5842	106	74	3	3	NUM
fnp-5842	106	75	institute	institute	PROPN
fnp-5842	106	76	of	of	ADP
fnp-5842	106	77	neuropathology	neuropathology	NOUN
fnp-5842	106	78	,	,	PUNCT
fnp-5842	106	79	university	university	NOUN
fnp-5842	106	80	medical	medical	ADJ
fnp-5842	106	81	center	center	PROPN
fnp-5842	106	82	hamburg	hamburg	PROPN
fnp-5842	106	83	-	-	PUNCT
fnp-5842	106	84	eppendorf	eppendorf	PROPN
fnp-5842	106	85	,	,	PUNCT
fnp-5842	106	86	hamburg	hamburg	PROPN
fnp-5842	106	87	,	,	PUNCT
fnp-5842	106	88	germany	germany	PROPN
fnp-5842	106	89	4	4	NUM
fnp-5842	106	90	center	center	NOUN
fnp-5842	106	91	for	for	ADP
fnp-5842	106	92	molecular	molecular	ADJ
fnp-5842	106	93	neurobiology	neurobiology	NOUN
fnp-5842	106	94	hamburg	hamburg	PROPN
fnp-5842	106	95	(	(	PUNCT
fnp-5842	106	96	zmnh	zmnh	PROPN
fnp-5842	106	97	)	)	PUNCT
fnp-5842	106	98	,	,	PUNCT
fnp-5842	106	99	university	university	NOUN
fnp-5842	106	100	medical	medical	ADJ
fnp-5842	106	101	center	center	PROPN
fnp-5842	106	102	hamburg	hamburg	PROPN
fnp-5842	106	103	-	-	PUNCT
fnp-5842	106	104	eppendorf	eppendorf	PROPN
fnp-5842	106	105	,	,	PUNCT
fnp-5842	106	106	hamburg	hamburg	PROPN
fnp-5842	106	107	,	,	PUNCT
fnp-5842	106	108	germany	germany	PROPN
fnp-5842	106	109	5	5	NUM
fnp-5842	106	110	section	section	NOUN
fnp-5842	106	111	of	of	ADP
fnp-5842	106	112	mass	mass	ADJ
fnp-5842	106	113	spectrometric	spectrometric	ADJ
fnp-5842	106	114	proteomics	proteomic	NOUN
fnp-5842	106	115	,	,	PUNCT
fnp-5842	106	116	university	university	NOUN
fnp-5842	106	117	medical	medical	ADJ
fnp-5842	106	118	center	center	PROPN
fnp-5842	106	119	hamburg	hamburg	PROPN
fnp-5842	106	120	-	-	PUNCT
fnp-5842	106	121	eppendorf	eppendorf	PROPN
fnp-5842	106	122	,	,	PUNCT
fnp-5842	106	123	hamburg	hamburg	PROPN
fnp-5842	106	124	,	,	PUNCT
fnp-5842	106	125	germany	germany	PROPN
fnp-5842	106	126	6	6	NUM
fnp-5842	106	127	institute	institute	PROPN
fnp-5842	106	128	of	of	ADP
fnp-5842	106	129	pathology	pathology	PROPN
fnp-5842	106	130	,	,	PUNCT
fnp-5842	106	131	department	department	NOUN
fnp-5842	106	132	of	of	ADP
fnp-5842	106	133	neuropathology	neuropathology	NOUN
fnp-5842	106	134	,	,	PUNCT
fnp-5842	106	135	tum	tum	PROPN
fnp-5842	106	136	school	school	NOUN
fnp-5842	106	137	of	of	ADP
fnp-5842	106	138	medicine	medicine	NOUN
fnp-5842	106	139	and	and	CCONJ
fnp-5842	106	140	health	health	NOUN
fnp-5842	106	141	,	,	PUNCT
fnp-5842	106	142	technical	technical	PROPN
fnp-5842	106	143	university	university	PROPN
fnp-5842	106	144	munich	munich	PROPN
fnp-5842	106	145	,	,	PUNCT
fnp-5842	106	146	munich	munich	PROPN
fnp-5842	106	147	,	,	PUNCT
fnp-5842	106	148	germany	germany	PROPN
fnp-5842	106	149	7	7	NUM
fnp-5842	106	150	institute	institute	PROPN
fnp-5842	106	151	of	of	ADP
fnp-5842	106	152	neuropathology	neuropathology	NOUN
fnp-5842	106	153	,	,	PUNCT
fnp-5842	106	154	university	university	NOUN
fnp-5842	106	155	hospital	hospital	NOUN
fnp-5842	106	156	münster	münster	NOUN
fnp-5842	106	157	,	,	PUNCT
fnp-5842	106	158	münster	münster	NOUN
fnp-5842	106	159	,	,	PUNCT
fnp-5842	106	160	germany	germany	PROPN
fnp-5842	106	161	*	*	PUNCT
fnp-5842	106	162	these	these	DET
fnp-5842	106	163	authors	author	NOUN
fnp-5842	106	164	contributed	contribute	VERB
fnp-5842	106	165	equally	equally	ADV
fnp-5842	106	166	to	to	ADP
fnp-5842	106	167	this	this	DET
fnp-5842	106	168	work	work	NOUN
fnp-5842	106	169	ependymomas	ependymomas	PROPN
fnp-5842	106	170	(	(	PUNCT
fnp-5842	106	171	epn	epn	PROPN
fnp-5842	106	172	)	)	PUNCT
fnp-5842	106	173	of	of	ADP
fnp-5842	106	174	the	the	DET
fnp-5842	106	175	spinal	spinal	ADJ
fnp-5842	106	176	cord	cord	NOUN
fnp-5842	106	177	encompass	encompass	VERB
fnp-5842	106	178	multiple	multiple	ADJ
fnp-5842	106	179	types	type	NOUN
fnp-5842	106	180	and	and	CCONJ
fnp-5842	106	181	subtypes	subtype	NOUN
fnp-5842	106	182	with	with	ADP
fnp-5842	106	183	distinct	distinct	ADJ
fnp-5842	106	184	histological	histological	ADJ
fnp-5842	106	185	,	,	PUNCT
fnp-5842	106	186	molecular	molecular	ADJ
fnp-5842	106	187	and	and	CCONJ
fnp-5842	106	188	clinical	clinical	ADJ
fnp-5842	106	189	features	feature	NOUN
fnp-5842	106	190	.	.	PUNCT
fnp-5842	107	1	apart	apart	ADV
fnp-5842	107	2	from	from	ADP
fnp-5842	107	3	subependymomas	subependymomas	PROPN
fnp-5842	107	4	(	(	PUNCT
fnp-5842	107	5	cns	cns	X
fnp-5842	107	6	who	who	PRON
fnp-5842	107	7	 	 	SPACE
fnp-5842	107	8	1	1	NUM
fnp-5842	107	9	)	)	PUNCT
fnp-5842	107	10	,	,	PUNCT
fnp-5842	107	11	spinal	spinal	ADJ
fnp-5842	107	12	epn	epn	NOUN
fnp-5842	107	13	,	,	PUNCT
fnp-5842	107	14	and	and	CCONJ
fnp-5842	107	15	myxopapillary	myxopapillary	ADJ
fnp-5842	107	16	epn	epn	PROPN
fnp-5842	107	17	(	(	PUNCT
fnp-5842	107	18	both	both	CCONJ
fnp-5842	107	19	cns	cns	VERB
fnp-5842	107	20	who	who	PRON
fnp-5842	107	21	 	 	SPACE
fnp-5842	107	22	2	2	NUM
fnp-5842	107	23	)	)	PUNCT
fnp-5842	107	24	,	,	PUNCT
fnp-5842	107	25	spinal	spinal	ADJ
fnp-5842	107	26	epn	epn	PROPN
fnp-5842	107	27	with	with	ADP
fnp-5842	107	28	mycn	mycn	NOUN
fnp-5842	107	29	amplification	amplification	NOUN
fnp-5842	107	30	have	have	AUX
fnp-5842	107	31	been	be	AUX
fnp-5842	107	32	identified	identify	VERB
fnp-5842	107	33	as	as	ADP
fnp-5842	107	34	the	the	DET
fnp-5842	107	35	most	most	ADV
fnp-5842	107	36	aggressive	aggressive	ADJ
fnp-5842	107	37	type	type	NOUN
fnp-5842	107	38	in	in	ADP
fnp-5842	107	39	the	the	DET
fnp-5842	107	40	spinal	spinal	NOUN
fnp-5842	107	41	cord	cord	NOUN
fnp-5842	107	42	.	.	PUNCT
fnp-5842	108	1	the	the	DET
fnp-5842	108	2	latter	latter	ADJ
fnp-5842	108	3	include	include	VERB
fnp-5842	108	4	most	most	ADJ
fnp-5842	108	5	of	of	ADP
fnp-5842	108	6	the	the	DET
fnp-5842	108	7	spinal	spinal	ADJ
fnp-5842	108	8	tumors	tumor	NOUN
fnp-5842	108	9	that	that	PRON
fnp-5842	108	10	had	have	AUX
fnp-5842	108	11	been	be	AUX
fnp-5842	108	12	diagnosed	diagnose	VERB
fnp-5842	108	13	as	as	ADP
fnp-5842	108	14	‘	'	PUNCT
fnp-5842	108	15	anaplastic	anaplastic	ADJ
fnp-5842	108	16	ependymoma	ependymoma	NOUN
fnp-5842	108	17	(	(	PUNCT
fnp-5842	108	18	cns	cns	X
fnp-5842	108	19	who	who	PRON
fnp-5842	108	20	 	 	SPACE
fnp-5842	108	21	3	3	NUM
fnp-5842	108	22	)	)	PUNCT
fnp-5842	108	23	’	'	PUNCT
fnp-5842	108	24	in	in	ADP
fnp-5842	108	25	the	the	DET
fnp-5842	108	26	pre	pre	ADJ
fnp-5842	108	27	-	-	ADJ
fnp-5842	108	28	molecular	molecular	ADJ
fnp-5842	108	29	era	era	NOUN
fnp-5842	108	30	.	.	PUNCT
fnp-5842	109	1	while	while	SCONJ
fnp-5842	109	2	amplifications	amplification	NOUN
fnp-5842	109	3	of	of	ADP
fnp-5842	109	4	mycn	mycn	NOUN
fnp-5842	109	5	therefore	therefore	ADV
fnp-5842	109	6	need	need	VERB
fnp-5842	109	7	to	to	PART
fnp-5842	109	8	be	be	AUX
fnp-5842	109	9	investigated	investigate	VERB
fnp-5842	109	10	specifically	specifically	ADV
fnp-5842	109	11	,	,	PUNCT
fnp-5842	109	12	global	global	ADJ
fnp-5842	109	13	dna	dna	PROPN
fnp-5842	109	14	methylation	methylation	NOUN
fnp-5842	109	15	profiling	profiling	NOUN
fnp-5842	109	16	has	have	AUX
fnp-5842	109	17	emerged	emerge	VERB
fnp-5842	109	18	as	as	ADP
fnp-5842	109	19	a	a	DET
fnp-5842	109	20	valuable	valuable	ADJ
fnp-5842	109	21	tool	tool	NOUN
fnp-5842	109	22	to	to	PART
fnp-5842	109	23	classify	classify	VERB
fnp-5842	109	24	epn	epn	PROPN
fnp-5842	109	25	.	.	PUNCT
fnp-5842	110	1	here	here	ADV
fnp-5842	110	2	,	,	PUNCT
fnp-5842	110	3	in	in	ADP
fnp-5842	110	4	depth	depth	NOUN
fnp-5842	110	5	analysis	analysis	NOUN
fnp-5842	110	6	of	of	ADP
fnp-5842	110	7	the	the	DET
fnp-5842	110	8	methylome	methylome	NOUN
fnp-5842	110	9	and	and	CCONJ
fnp-5842	110	10	the	the	DET
fnp-5842	110	11	proteome	proteome	NOUN
fnp-5842	110	12	of	of	ADP
fnp-5842	110	13	spinal	spinal	ADJ
fnp-5842	110	14	cord	cord	NOUN
fnp-5842	110	15	epn	epn	PROPN
fnp-5842	110	16	revealed	reveal	VERB
fnp-5842	110	17	a	a	DET
fnp-5842	110	18	novel	novel	ADJ
fnp-5842	110	19	distinct	distinct	ADJ
fnp-5842	110	20	molecular	molecular	ADJ
fnp-5842	110	21	epn	epn	NOUN
fnp-5842	110	22	subtype	subtype	NOUN
fnp-5842	110	23	.	.	PUNCT
fnp-5842	111	1	unsupervised	unsupervised	ADJ
fnp-5842	111	2	clustering	clustering	NOUN
fnp-5842	111	3	of	of	ADP
fnp-5842	111	4	integrated	integrate	VERB
fnp-5842	111	5	methylation	methylation	NOUN
fnp-5842	111	6	data	datum	NOUN
fnp-5842	111	7	of	of	ADP
fnp-5842	111	8	epn	epn	PROPN
fnp-5842	111	9	revealed	reveal	VERB
fnp-5842	111	10	a	a	DET
fnp-5842	111	11	distinct	distinct	ADJ
fnp-5842	111	12	cluster	cluster	NOUN
fnp-5842	111	13	of	of	ADP
fnp-5842	111	14	cases	case	NOUN
fnp-5842	111	15	,	,	PUNCT
fnp-5842	111	16	that	that	SCONJ
fnp-5842	111	17	the	the	DET
fnp-5842	111	18	established	establish	VERB
fnp-5842	111	19	brain	brain	NOUN
fnp-5842	111	20	tumor	tumor	NOUN
fnp-5842	111	21	classifier	classifier	NOUN
fnp-5842	111	22	(	(	PUNCT
fnp-5842	111	23	capper	capper	NOUN
fnp-5842	111	24	et	et	PROPN
fnp-5842	111	25	al	al	PROPN
fnp-5842	111	26	.	.	PUNCT
fnp-5842	111	27	(	(	PUNCT
fnp-5842	111	28	2018	2018	NUM
fnp-5842	111	29	)	)	PUNCT
fnp-5842	111	30	)	)	PUNCT
fnp-5842	111	31	mainly	mainly	ADV
fnp-5842	111	32	defined	define	VERB
fnp-5842	111	33	as	as	ADP
fnp-5842	111	34	spinal	spinal	ADJ
fnp-5842	111	35	subependymomas	subependymoma	NOUN
fnp-5842	111	36	.	.	PUNCT
fnp-5842	112	1	further	further	ADJ
fnp-5842	112	2	liquid	liquid	ADJ
fnp-5842	112	3	chromatography	chromatography	NOUN
fnp-5842	112	4	mass	mass	NOUN
fnp-5842	112	5	spectrometry	spectrometry	NOUN
fnp-5842	112	6	-	-	PUNCT
fnp-5842	112	7	based	base	VERB
fnp-5842	112	8	proteomics	proteomic	NOUN
fnp-5842	112	9	measurements	measurement	NOUN
fnp-5842	112	10	were	be	AUX
fnp-5842	112	11	conducted	conduct	VERB
fnp-5842	112	12	and	and	CCONJ
fnp-5842	112	13	an	an	DET
fnp-5842	112	14	unsupervised	unsupervised	ADJ
fnp-5842	112	15	analyses	analysis	NOUN
fnp-5842	112	16	of	of	ADP
fnp-5842	112	17	matched	match	VERB
fnp-5842	112	18	proteome	proteome	PROPN
fnp-5842	112	19	data	datum	NOUN
fnp-5842	112	20	revealed	reveal	VERB
fnp-5842	112	21	a	a	DET
fnp-5842	112	22	similarity	similarity	NOUN
fnp-5842	112	23	of	of	ADP
fnp-5842	112	24	the	the	DET
fnp-5842	112	25	corresponding	correspond	VERB
fnp-5842	112	26	samples	sample	NOUN
fnp-5842	112	27	with	with	ADP
fnp-5842	112	28	spinal	spinal	ADJ
fnp-5842	112	29	epn	epn	NOUN
fnp-5842	112	30	,	,	PUNCT
fnp-5842	112	31	mycn	mycn	NOUN
fnp-5842	112	32	amplified	amplify	VERB
fnp-5842	112	33	.	.	PUNCT
fnp-5842	113	1	reevaluation	reevaluation	NOUN
fnp-5842	113	2	of	of	ADP
fnp-5842	113	3	histological	histological	ADJ
fnp-5842	113	4	features	feature	NOUN
fnp-5842	113	5	showed	show	VERB
fnp-5842	113	6	an	an	DET
fnp-5842	113	7	anaplastic	anaplastic	ADJ
fnp-5842	113	8	histology	histology	NOUN
fnp-5842	113	9	with	with	ADP
fnp-5842	113	10	high	high	ADJ
fnp-5842	113	11	ki67	ki67	PROPN
fnp-5842	113	12	indices	index	NOUN
fnp-5842	113	13	and	and	CCONJ
fnp-5842	113	14	positive	positive	ADJ
fnp-5842	113	15	nuclear	nuclear	ADJ
fnp-5842	113	16	staining	stain	VERB
fnp-5842	113	17	for	for	ADP
fnp-5842	113	18	mycn	mycn	NOUN
fnp-5842	113	19	and	and	CCONJ
fnp-5842	113	20	olig2	olig2	PROPN
fnp-5842	113	21	,	,	PUNCT
fnp-5842	113	22	which	which	PRON
fnp-5842	113	23	has	have	AUX
fnp-5842	113	24	not	not	PART
fnp-5842	113	25	been	be	AUX
fnp-5842	113	26	described	describe	VERB
fnp-5842	113	27	for	for	ADP
fnp-5842	113	28	subependymomas	subependymoma	NOUN
fnp-5842	113	29	before	before	ADV
fnp-5842	113	30	.	.	PUNCT
fnp-5842	114	1	although	although	SCONJ
fnp-5842	114	2	our	our	PRON
fnp-5842	114	3	cases	case	NOUN
fnp-5842	114	4	had	have	VERB
fnp-5842	114	5	anaplastic	anaplastic	ADJ
fnp-5842	114	6	features	feature	NOUN
fnp-5842	114	7	and	and	CCONJ
fnp-5842	114	8	showed	show	VERB
fnp-5842	114	9	expression	expression	NOUN
fnp-5842	114	10	of	of	ADP
fnp-5842	114	11	mycn	mycn	NOUN
fnp-5842	114	12	protein	protein	NOUN
fnp-5842	114	13	by	by	ADP
fnp-5842	114	14	immunohistochemistry	immunohistochemistry	NOUN
fnp-5842	114	15	,	,	PUNCT
fnp-5842	114	16	mycn	mycn	NOUN
fnp-5842	114	17	amplifications	amplification	NOUN
fnp-5842	114	18	were	be	AUX
fnp-5842	114	19	neither	neither	CCONJ
fnp-5842	114	20	detectable	detectable	ADJ
fnp-5842	114	21	by	by	ADP
fnp-5842	114	22	fish	fish	NOUN
fnp-5842	114	23	nor	nor	CCONJ
fnp-5842	114	24	by	by	ADP
fnp-5842	114	25	whole	whole	ADJ
fnp-5842	114	26	genome	genome	NOUN
fnp-5842	114	27	copy	copy	NOUN
fnp-5842	114	28	number	number	NOUN
fnp-5842	114	29	profiles	profile	NOUN
fnp-5842	114	30	.	.	PUNCT
fnp-5842	115	1	limited	limit	VERB
fnp-5842	115	2	follow	follow	VERB
fnp-5842	115	3	up	up	ADP
fnp-5842	115	4	data	datum	NOUN
fnp-5842	115	5	indicated	indicate	VERB
fnp-5842	115	6	that	that	SCONJ
fnp-5842	115	7	respective	respective	ADJ
fnp-5842	115	8	cases	case	NOUN
fnp-5842	115	9	may	may	AUX
fnp-5842	115	10	not	not	PART
fnp-5842	115	11	relapse	relapse	VERB
fnp-5842	115	12	as	as	ADV
fnp-5842	115	13	commonly	commonly	ADV
fnp-5842	115	14	as	as	SCONJ
fnp-5842	115	15	mycn	mycn	NOUN
fnp-5842	115	16	amplified	amplify	VERB
fnp-5842	115	17	epn	epn	NOUN
fnp-5842	115	18	.	.	PUNCT
fnp-5842	116	1	we	we	PRON
fnp-5842	116	2	report	report	VERB
fnp-5842	116	3	a	a	DET
fnp-5842	116	4	series	series	NOUN
fnp-5842	116	5	of	of	ADP
fnp-5842	116	6	spinal	spinal	ADJ
fnp-5842	116	7	epn	epn	NOUN
fnp-5842	116	8	displaying	display	VERB
fnp-5842	116	9	distinct	distinct	ADJ
fnp-5842	116	10	histomorphology	histomorphology	NOUN
fnp-5842	116	11	,	,	PUNCT
fnp-5842	116	12	epigenetic	epigenetic	ADJ
fnp-5842	116	13	and	and	CCONJ
fnp-5842	116	14	proteomic	proteomic	ADJ
fnp-5842	116	15	patterns	pattern	NOUN
fnp-5842	116	16	and	and	CCONJ
fnp-5842	116	17	propose	propose	VERB
fnp-5842	116	18	the	the	DET
fnp-5842	116	19	provisional	provisional	ADJ
fnp-5842	116	20	designation	designation	NOUN
fnp-5842	116	21	as	as	ADP
fnp-5842	116	22	mycn	mycn	NOUN
fnp-5842	116	23	-	-	PUNCT
fnp-5842	116	24	like	like	ADJ
fnp-5842	116	25	spinal	spinal	NOUN
fnp-5842	116	26	ependymoma	ependymoma	NOUN
fnp-5842	116	27	(	(	PUNCT
fnp-5842	116	28	sp	sp	NOUN
fnp-5842	116	29	-	-	PUNCT
fnp-5842	116	30	epn	epn	NOUN
fnp-5842	116	31	-	-	PUNCT
fnp-5842	116	32	mycn	mycn	NOUN
fnp-5842	116	33	-	-	PUNCT
fnp-5842	116	34	like	like	ADJ
fnp-5842	116	35	)	)	PUNCT
fnp-5842	116	36	.	.	PUNCT
fnp-5842	117	1	more	more	ADJ
fnp-5842	117	2	in	in	ADP
fnp-5842	117	3	-	-	PUNCT
fnp-5842	117	4	depth	depth	NOUN
fnp-5842	117	5	investigations	investigation	NOUN
fnp-5842	117	6	are	be	AUX
fnp-5842	117	7	warranted	warrant	VERB
fnp-5842	117	8	to	to	PART
fnp-5842	117	9	uncover	uncover	VERB
fnp-5842	117	10	e.g.	e.g.	ADJ
fnp-5842	117	11	genetic	genetic	ADJ
fnp-5842	117	12	drivers	driver	NOUN
fnp-5842	117	13	of	of	ADP
fnp-5842	117	14	the	the	DET
fnp-5842	117	15	tumors	tumor	NOUN
fnp-5842	117	16	and	and	CCONJ
fnp-5842	117	17	clinical	clinical	ADJ
fnp-5842	117	18	outcomes	outcome	NOUN
fnp-5842	117	19	of	of	ADP
fnp-5842	117	20	respective	respective	ADJ
fnp-5842	117	21	patients	patient	NOUN
fnp-5842	117	22	.	.	PUNCT
fnp-5842	118	1	p08	p08	PROPN
fnp-5842	118	2	free	free	ADJ
fnp-5842	118	3	neuropathol	neuropathol	NOUN
fnp-5842	118	4	5:19:17	5:19:17	NUM
fnp-5842	118	5	integrated	integrate	VERB
fnp-5842	118	6	analyses	analysis	NOUN
fnp-5842	118	7	reveal	reveal	VERB
fnp-5842	118	8	two	two	NUM
fnp-5842	118	9	molecularly	molecularly	ADV
fnp-5842	118	10	and	and	CCONJ
fnp-5842	118	11	clinically	clinically	ADV
fnp-5842	118	12	distinct	distinct	ADJ
fnp-5842	118	13	subtypes	subtype	NOUN
fnp-5842	118	14	of	of	ADP
fnp-5842	118	15	h3	h3	NOUN
fnp-5842	118	16	k27m	k27m	NOUN
fnp-5842	118	17	-	-	ADJ
fnp-5842	118	18	mutant	mutant	ADJ
fnp-5842	118	19	diffuse	diffuse	NOUN
fnp-5842	118	20	midline	midline	NOUN
fnp-5842	118	21	gliomas	glioma	NOUN
fnp-5842	118	22	with	with	ADP
fnp-5842	118	23	prognostic	prognostic	ADJ
fnp-5842	118	24	significance	significance	NOUN
fnp-5842	118	25	lotte	lotte	PROPN
fnp-5842	118	26	stegat1	stegat1	PROPN
fnp-5842	118	27	,	,	PUNCT
fnp-5842	118	28	alicia	alicia	PROPN
fnp-5842	118	29	eckhardt1,2	eckhardt1,2	PROPN
fnp-5842	118	30	,	,	PUNCT
fnp-5842	118	31	antonia	antonia	PROPN
fnp-5842	118	32	gocke3,4	gocke3,4	PROPN
fnp-5842	118	33	,	,	PUNCT
fnp-5842	118	34	sina	sina	PROPN
fnp-5842	118	35	neyazi2,5	neyazi2,5	PROPN
fnp-5842	118	36	,	,	PUNCT
fnp-5842	118	37	lara	lara	PROPN
fnp-5842	118	38	pohl2,5	pohl2,5	PROPN
fnp-5842	118	39	,	,	PUNCT
fnp-5842	118	40	simone	simone	PROPN
fnp-5842	118	41	schmid6,7	schmid6,7	PROPN
fnp-5842	118	42	,	,	PUNCT
fnp-5842	118	43	matthias	matthias	PROPN
fnp-5842	118	44	dottermusch1,3	dottermusch1,3	PROPN
fnp-5842	118	45	,	,	PUNCT
fnp-5842	118	46	stephan	stephan	PROPN
fnp-5842	118	47	frank8	frank8	PROPN
fnp-5842	118	48	,	,	PUNCT
fnp-5842	118	49	hans	hans	PROPN
fnp-5842	118	50	pinnschmidt9	pinnschmidt9	PROPN
fnp-5842	118	51	,	,	PUNCT
fnp-5842	118	52	jochen	jochen	PROPN
fnp-5842	118	53	herms10	herms10	PROPN
fnp-5842	118	54	,	,	PUNCT
fnp-5842	118	55	markus	markus	PROPN
fnp-5842	118	56	glatzel1	glatzel1	PROPN
fnp-5842	118	57	,	,	PUNCT
fnp-5842	118	58	matija	matija	NOUN
fnp-5842	118	59	snuderl11	snuderl11	NOUN
fnp-5842	118	60	,	,	PUNCT
fnp-5842	118	61	leonille	leonille	NOUN
fnp-5842	118	62	schweizer12,13,14	schweizer12,13,14	ADV
fnp-5842	118	63	,	,	PUNCT
fnp-5842	118	64	christian	christian	PROPN
fnp-5842	118	65	thomas15	thomas15	PROPN
fnp-5842	118	66	,	,	PUNCT
fnp-5842	118	67	julia	julia	PROPN
fnp-5842	118	68	neumann1,3	neumann1,3	PROPN
fnp-5842	118	69	,	,	PUNCT
fnp-5842	118	70	mario	mario	PROPN
fnp-5842	118	71	m.	m.	PROPN
fnp-5842	118	72	dorostkar10,16	dorostkar10,16	PROPN
fnp-5842	118	73	,	,	PUNCT
fnp-5842	118	74	ulrich	ulrich	PROPN
fnp-5842	118	75	schüller1,2,5	schüller1,2,5	NOUN
fnp-5842	118	76	,	,	PUNCT
fnp-5842	118	77	annika	annika	PROPN
fnp-5842	118	78	k.	k.	PROPN
fnp-5842	118	79	wefers1,17,18	wefers1,17,18	PROPN
fnp-5842	118	80	1	1	NUM
fnp-5842	118	81	institute	institute	PROPN
fnp-5842	118	82	of	of	ADP
fnp-5842	118	83	neuropathology	neuropathology	NOUN
fnp-5842	118	84	,	,	PUNCT
fnp-5842	118	85	university	university	NOUN
fnp-5842	118	86	medical	medical	ADJ
fnp-5842	118	87	center	center	PROPN
fnp-5842	118	88	hamburg	hamburg	PROPN
fnp-5842	118	89	-	-	PUNCT
fnp-5842	118	90	eppendorf	eppendorf	PROPN
fnp-5842	118	91	,	,	PUNCT
fnp-5842	118	92	hamburg	hamburg	PROPN
fnp-5842	118	93	,	,	PUNCT
fnp-5842	118	94	germany	germany	PROPN
fnp-5842	118	95	2	2	NUM
fnp-5842	118	96	research	research	NOUN
fnp-5842	118	97	institute	institute	NOUN
fnp-5842	118	98	children	child	NOUN
fnp-5842	118	99	’s	’s	PART
fnp-5842	118	100	cancer	cancer	NOUN
fnp-5842	118	101	center	center	PROPN
fnp-5842	118	102	hamburg	hamburg	PROPN
fnp-5842	118	103	,	,	PUNCT
fnp-5842	118	104	martinistrasse	martinistrasse	VERB
fnp-5842	118	105	52	52	NUM
fnp-5842	118	106	,	,	PUNCT
fnp-5842	118	107	n63	n63	PROPN
fnp-5842	118	108	(	(	PUNCT
fnp-5842	118	109	hpi	hpi	PROPN
fnp-5842	118	110	)	)	PUNCT
fnp-5842	118	111	,	,	PUNCT
fnp-5842	118	112	20251	20251	NUM
fnp-5842	118	113	hamburg	hamburg	PROPN
fnp-5842	118	114	,	,	PUNCT
fnp-5842	118	115	germany	germany	PROPN
fnp-5842	118	116	3	3	NUM
fnp-5842	118	117	center	center	NOUN
fnp-5842	118	118	for	for	ADP
fnp-5842	118	119	molecular	molecular	ADJ
fnp-5842	118	120	neurobiology	neurobiology	NOUN
fnp-5842	118	121	hamburg	hamburg	PROPN
fnp-5842	118	122	,	,	PUNCT
fnp-5842	118	123	university	university	NOUN
fnp-5842	118	124	medical	medical	ADJ
fnp-5842	118	125	center	center	PROPN
fnp-5842	118	126	hamburg	hamburg	PROPN
fnp-5842	118	127	-	-	PUNCT
fnp-5842	118	128	eppendorf	eppendorf	PROPN
fnp-5842	118	129	,	,	PUNCT
fnp-5842	118	130	hamburg	hamburg	PROPN
fnp-5842	118	131	,	,	PUNCT
fnp-5842	118	132	germany	germany	PROPN
fnp-5842	118	133	4	4	NUM
fnp-5842	118	134	section	section	NOUN
fnp-5842	118	135	of	of	ADP
fnp-5842	118	136	mass	mass	ADJ
fnp-5842	118	137	spectrometric	spectrometric	ADJ
fnp-5842	118	138	proteomics	proteomic	NOUN
fnp-5842	118	139	,	,	PUNCT
fnp-5842	118	140	university	university	NOUN
fnp-5842	118	141	medical	medical	ADJ
fnp-5842	118	142	center	center	PROPN
fnp-5842	118	143	hamburg	hamburg	PROPN
fnp-5842	118	144	-	-	PUNCT
fnp-5842	118	145	eppendorf	eppendorf	PROPN
fnp-5842	118	146	,	,	PUNCT
fnp-5842	118	147	hamburg	hamburg	PROPN
fnp-5842	118	148	,	,	PUNCT
fnp-5842	118	149	germany	germany	PROPN
fnp-5842	118	150	5	5	NUM
fnp-5842	118	151	department	department	NOUN
fnp-5842	118	152	of	of	ADP
fnp-5842	118	153	pediatric	pediatric	ADJ
fnp-5842	118	154	hematology	hematology	NOUN
fnp-5842	118	155	and	and	CCONJ
fnp-5842	118	156	oncology	oncology	NOUN
fnp-5842	118	157	,	,	PUNCT
fnp-5842	118	158	university	university	NOUN
fnp-5842	118	159	medical	medical	ADJ
fnp-5842	118	160	center	center	PROPN
fnp-5842	118	161	hamburg	hamburg	PROPN
fnp-5842	118	162	-	-	PUNCT
fnp-5842	118	163	eppendorf	eppendorf	PROPN
fnp-5842	118	164	,	,	PUNCT
fnp-5842	118	165	hamburg	hamburg	PROPN
fnp-5842	118	166	,	,	PUNCT
fnp-5842	118	167	germany	germany	PROPN
fnp-5842	118	168	6	6	NUM
fnp-5842	118	169	charité	charité	PROPN
fnp-5842	118	170	universitätsmedizin	universitätsmedizin	PROPN
fnp-5842	118	171	berlin	berlin	PROPN
fnp-5842	118	172	,	,	PUNCT
fnp-5842	118	173	corporate	corporate	ADJ
fnp-5842	118	174	member	member	NOUN
fnp-5842	118	175	of	of	ADP
fnp-5842	118	176	freie	freie	PROPN
fnp-5842	118	177	universität	universität	PROPN
fnp-5842	118	178	berlin	berlin	PROPN
fnp-5842	118	179	,	,	PUNCT
fnp-5842	118	180	humboldt	humboldt	PROPN
fnp-5842	118	181	-	-	PUNCT
fnp-5842	118	182	universität	universität	PROPN
fnp-5842	118	183	zu	zu	NOUN
fnp-5842	118	184	berlin	berlin	PROPN
fnp-5842	118	185	,	,	PUNCT
fnp-5842	118	186	and	and	CCONJ
fnp-5842	118	187	berlin	berlin	PROPN
fnp-5842	118	188	institute	institute	PROPN
fnp-5842	118	189	of	of	ADP
fnp-5842	118	190	health	health	PROPN
fnp-5842	118	191	,	,	PUNCT
fnp-5842	118	192	department	department	NOUN
fnp-5842	118	193	of	of	ADP
fnp-5842	118	194	neuropathology	neuropathology	NOUN
fnp-5842	118	195	,	,	PUNCT
fnp-5842	118	196	berlin	berlin	PROPN
fnp-5842	118	197	,	,	PUNCT
fnp-5842	118	198	germany	germany	PROPN
fnp-5842	118	199	7	7	NUM
fnp-5842	118	200	german	german	ADJ
fnp-5842	118	201	cancer	cancer	NOUN
fnp-5842	118	202	consortium	consortium	NOUN
fnp-5842	118	203	(	(	PUNCT
fnp-5842	118	204	dktk	dktk	NOUN
fnp-5842	118	205	)	)	PUNCT
fnp-5842	118	206	,	,	PUNCT
fnp-5842	118	207	partner	partner	NOUN
fnp-5842	118	208	site	site	NOUN
fnp-5842	118	209	berlin	berlin	PROPN
fnp-5842	118	210	,	,	PUNCT
fnp-5842	118	211	and	and	CCONJ
fnp-5842	118	212	german	german	ADJ
fnp-5842	118	213	cancer	cancer	NOUN
fnp-5842	118	214	research	research	NOUN
fnp-5842	118	215	center	center	NOUN
fnp-5842	118	216	(	(	PUNCT
fnp-5842	118	217	dkfz	dkfz	PROPN
fnp-5842	118	218	)	)	PUNCT
fnp-5842	118	219	,	,	PUNCT
fnp-5842	118	220	heidelberg	heidelberg	PROPN
fnp-5842	118	221	,	,	PUNCT
fnp-5842	118	222	germany	germany	PROPN
fnp-5842	118	223	8	8	NUM
fnp-5842	118	224	department	department	PROPN
fnp-5842	118	225	of	of	ADP
fnp-5842	118	226	neuropathology	neuropathology	NOUN
fnp-5842	118	227	,	,	PUNCT
fnp-5842	118	228	institute	institute	PROPN
fnp-5842	118	229	of	of	ADP
fnp-5842	118	230	pathology	pathology	PROPN
fnp-5842	118	231	,	,	PUNCT
fnp-5842	118	232	basel	basel	PROPN
fnp-5842	118	233	university	university	PROPN
fnp-5842	118	234	hospital	hospital	NOUN
fnp-5842	118	235	,	,	PUNCT
fnp-5842	118	236	basel	basel	PROPN
fnp-5842	118	237	,	,	PUNCT
fnp-5842	118	238	switzerland	switzerland	PROPN
fnp-5842	118	239	9	9	NUM
fnp-5842	118	240	institute	institute	PROPN
fnp-5842	118	241	of	of	ADP
fnp-5842	118	242	medical	medical	PROPN
fnp-5842	118	243	biometry	biometry	NOUN
fnp-5842	118	244	and	and	CCONJ
fnp-5842	118	245	epidemiology	epidemiology	NOUN
fnp-5842	118	246	,	,	PUNCT
fnp-5842	118	247	center	center	NOUN
fnp-5842	118	248	for	for	ADP
fnp-5842	118	249	experimental	experimental	ADJ
fnp-5842	118	250	medicine	medicine	NOUN
fnp-5842	118	251	,	,	PUNCT
fnp-5842	118	252	university	university	NOUN
fnp-5842	118	253	medical	medical	ADJ
fnp-5842	118	254	center	center	PROPN
fnp-5842	118	255	hamburg	hamburg	PROPN
fnp-5842	118	256	-	-	PUNCT
fnp-5842	118	257	eppendorf	eppendorf	PROPN
fnp-5842	118	258	,	,	PUNCT
fnp-5842	118	259	hamburg	hamburg	PROPN
fnp-5842	118	260	,	,	PUNCT
fnp-5842	118	261	germany	germany	PROPN
fnp-5842	118	262	10	10	NUM
fnp-5842	118	263	center	center	NOUN
fnp-5842	118	264	for	for	ADP
fnp-5842	118	265	neuropathology	neuropathology	NOUN
fnp-5842	118	266	and	and	CCONJ
fnp-5842	118	267	prion	prion	NOUN
fnp-5842	118	268	research	research	NOUN
fnp-5842	118	269	,	,	PUNCT
fnp-5842	118	270	ludwig	ludwig	PROPN
fnp-5842	118	271	-	-	PUNCT
fnp-5842	118	272	maximilians	maximilians	PROPN
fnp-5842	118	273	-	-	PUNCT
fnp-5842	118	274	university	university	NOUN
fnp-5842	118	275	,	,	PUNCT
fnp-5842	118	276	munich	munich	PROPN
fnp-5842	118	277	,	,	PUNCT
fnp-5842	118	278	germany	germany	PROPN
fnp-5842	118	279	11	11	NUM
fnp-5842	118	280	department	department	PROPN
fnp-5842	118	281	of	of	ADP
fnp-5842	118	282	pathology	pathology	PROPN
fnp-5842	118	283	,	,	PUNCT
fnp-5842	118	284	nyu	nyu	PROPN
fnp-5842	118	285	langone	langone	PROPN
fnp-5842	118	286	medical	medical	ADJ
fnp-5842	118	287	center	center	NOUN
fnp-5842	118	288	,	,	PUNCT
fnp-5842	118	289	new	new	PROPN
fnp-5842	118	290	york	york	PROPN
fnp-5842	118	291	,	,	PUNCT
fnp-5842	118	292	usa	usa	PROPN
fnp-5842	118	293	12	12	NUM
fnp-5842	118	294	edinger	edinger	PROPN
fnp-5842	118	295	institute	institute	PROPN
fnp-5842	118	296	(	(	PUNCT
fnp-5842	118	297	institute	institute	PROPN
fnp-5842	118	298	of	of	ADP
fnp-5842	118	299	neurology	neurology	NOUN
fnp-5842	118	300	)	)	PUNCT
fnp-5842	118	301	,	,	PUNCT
fnp-5842	118	302	university	university	NOUN
fnp-5842	118	303	hospital	hospital	NOUN
fnp-5842	118	304	frankfurt	frankfurt	PROPN
fnp-5842	118	305	,	,	PUNCT
fnp-5842	118	306	goethe	goethe	PROPN
fnp-5842	118	307	university	university	PROPN
fnp-5842	118	308	,	,	PUNCT
fnp-5842	118	309	frankfurt	frankfurt	PROPN
fnp-5842	118	310	am	be	AUX
fnp-5842	118	311	main	main	ADJ
fnp-5842	118	312	,	,	PUNCT
fnp-5842	118	313	germany	germany	PROPN
fnp-5842	118	314	13	13	NUM
fnp-5842	118	315	german	german	ADJ
fnp-5842	118	316	cancer	cancer	NOUN
fnp-5842	118	317	consortium	consortium	NOUN
fnp-5842	118	318	(	(	PUNCT
fnp-5842	118	319	dktk	dktk	NOUN
fnp-5842	118	320	)	)	PUNCT
fnp-5842	118	321	,	,	PUNCT
fnp-5842	118	322	partner	partner	NOUN
fnp-5842	118	323	site	site	NOUN
fnp-5842	118	324	frankfurt	frankfurt	PROPN
fnp-5842	118	325	-	-	PUNCT
fnp-5842	118	326	mainz	mainz	PROPN
fnp-5842	118	327	,	,	PUNCT
fnp-5842	118	328	german	german	ADJ
fnp-5842	118	329	cancer	cancer	NOUN
fnp-5842	118	330	research	research	NOUN
fnp-5842	118	331	center	center	NOUN
fnp-5842	118	332	(	(	PUNCT
fnp-5842	118	333	dkfz	dkfz	PROPN
fnp-5842	118	334	)	)	PUNCT
fnp-5842	118	335	,	,	PUNCT
fnp-5842	118	336	heidelberg	heidelberg	PROPN
fnp-5842	118	337	,	,	PUNCT
fnp-5842	118	338	germany	germany	PROPN
fnp-5842	118	339	14	14	NUM
fnp-5842	118	340	frankfurt	frankfurt	PROPN
fnp-5842	118	341	cancer	cancer	PROPN
fnp-5842	118	342	institute	institute	PROPN
fnp-5842	118	343	(	(	PUNCT
fnp-5842	118	344	fci	fci	PROPN
fnp-5842	118	345	)	)	PUNCT
fnp-5842	118	346	,	,	PUNCT
fnp-5842	118	347	frankfurt	frankfurt	PROPN
fnp-5842	118	348	am	be	AUX
fnp-5842	118	349	main	main	ADJ
fnp-5842	118	350	,	,	PUNCT
fnp-5842	118	351	germany	germany	PROPN
fnp-5842	118	352	15	15	NUM
fnp-5842	118	353	institute	institute	PROPN
fnp-5842	118	354	of	of	ADP
fnp-5842	118	355	neuropathology	neuropathology	NOUN
fnp-5842	118	356	,	,	PUNCT
fnp-5842	118	357	university	university	NOUN
fnp-5842	118	358	hospital	hospital	NOUN
fnp-5842	118	359	münster	münster	NOUN
fnp-5842	118	360	,	,	PUNCT
fnp-5842	118	361	münster	münster	NOUN
fnp-5842	118	362	,	,	PUNCT
fnp-5842	118	363	germany	germany	PROPN
fnp-5842	118	364	16	16	NUM
fnp-5842	118	365	karl	karl	PROPN
fnp-5842	118	366	landsteiner	landsteiner	PROPN
fnp-5842	118	367	privatuniversität	privatuniversität	PROPN
fnp-5842	118	368	für	für	PROPN
fnp-5842	118	369	gesundheitswissenschaften	gesundheitswissenschaften	VERB
fnp-5842	118	370	,	,	PUNCT
fnp-5842	118	371	st	st	PROPN
fnp-5842	118	372	.	.	PROPN
fnp-5842	118	373	pölten	pölten	PROPN
fnp-5842	118	374	,	,	PUNCT
fnp-5842	118	375	austria	austria	PROPN
fnp-5842	118	376	17	17	NUM
fnp-5842	118	377	mildred	mildre	VERB
fnp-5842	118	378	scheel	scheel	PROPN
fnp-5842	118	379	cancer	cancer	NOUN
fnp-5842	118	380	career	career	NOUN
fnp-5842	118	381	center	center	NOUN
fnp-5842	118	382	hatrics4	hatrics4	NOUN
fnp-5842	118	383	,	,	PUNCT
fnp-5842	118	384	university	university	NOUN
fnp-5842	118	385	medical	medical	ADJ
fnp-5842	118	386	center	center	PROPN
fnp-5842	118	387	hamburg	hamburg	PROPN
fnp-5842	118	388	-	-	PUNCT
fnp-5842	118	389	eppendorf	eppendorf	PROPN
fnp-5842	118	390	,	,	PUNCT
fnp-5842	118	391	hamburg	hamburg	PROPN
fnp-5842	118	392	,	,	PUNCT
fnp-5842	118	393	germany	germany	PROPN
fnp-5842	118	394	18	18	NUM
fnp-5842	118	395	present	present	ADJ
fnp-5842	118	396	address	address	NOUN
fnp-5842	118	397	:	:	PUNCT
fnp-5842	118	398	regensburg	regensburg	PROPN
fnp-5842	118	399	university	university	PROPN
fnp-5842	118	400	hospital	hospital	NOUN
fnp-5842	118	401	,	,	PUNCT
fnp-5842	118	402	department	department	NOUN
fnp-5842	118	403	of	of	ADP
fnp-5842	118	404	neuropathology	neuropathology	NOUN
fnp-5842	118	405	,	,	PUNCT
fnp-5842	118	406	regensburg	regensburg	PROPN
fnp-5842	118	407	,	,	PUNCT
fnp-5842	118	408	germany	germany	PROPN
fnp-5842	118	409	histone	histone	PROPN
fnp-5842	118	410	h3	h3	NOUN
fnp-5842	118	411	k27m	k27m	NOUN
fnp-5842	118	412	-	-	ADJ
fnp-5842	118	413	mutant	mutant	ADJ
fnp-5842	118	414	diffuse	diffuse	NOUN
fnp-5842	118	415	midline	midline	NOUN
fnp-5842	118	416	gliomas	glioma	NOUN
fnp-5842	118	417	(	(	PUNCT
fnp-5842	118	418	dmgs	dmgs	PROPN
fnp-5842	118	419	)	)	PUNCT
fnp-5842	118	420	are	be	AUX
fnp-5842	118	421	highly	highly	ADV
fnp-5842	118	422	malignant	malignant	ADJ
fnp-5842	118	423	tumours	tumour	NOUN
fnp-5842	118	424	arising	arise	VERB
fnp-5842	118	425	in	in	ADP
fnp-5842	118	426	the	the	DET
fnp-5842	118	427	midline	midline	NOUN
fnp-5842	118	428	structures	structure	NOUN
fnp-5842	118	429	of	of	ADP
fnp-5842	118	430	the	the	DET
fnp-5842	118	431	cns	cns	NOUN
fnp-5842	118	432	.	.	PUNCT
fnp-5842	119	1	recent	recent	ADJ
fnp-5842	119	2	studies	study	NOUN
fnp-5842	119	3	suggested	suggest	VERB
fnp-5842	119	4	that	that	SCONJ
fnp-5842	119	5	epigenetic	epigenetic	ADJ
fnp-5842	119	6	subgroups	subgroup	NOUN
fnp-5842	119	7	of	of	ADP
fnp-5842	119	8	dmgs	dmgs	NOUN
fnp-5842	119	9	can	can	AUX
fnp-5842	119	10	be	be	AUX
fnp-5842	119	11	distinguished	distinguish	VERB
fnp-5842	119	12	based	base	VERB
fnp-5842	119	13	on	on	ADP
fnp-5842	119	14	alterations	alteration	NOUN
fnp-5842	119	15	in	in	ADP
fnp-5842	119	16	the	the	DET
fnp-5842	119	17	mapk	mapk	NOUN
fnp-5842	119	18	-	-	PUNCT
fnp-5842	119	19	signalling	signal	VERB
fnp-5842	119	20	pathway	pathway	NOUN
fnp-5842	119	21	,	,	PUNCT
fnp-5842	119	22	tumour	tumour	NOUN
fnp-5842	119	23	localisation	localisation	NOUN
fnp-5842	119	24	,	,	PUNCT
fnp-5842	119	25	mutant	mutant	ADJ
fnp-5842	119	26	h3	h3	NOUN
fnp-5842	119	27	-	-	PUNCT
fnp-5842	119	28	gene	gene	NOUN
fnp-5842	119	29	,	,	PUNCT
fnp-5842	119	30	or	or	CCONJ
fnp-5842	119	31	overall	overall	ADJ
fnp-5842	119	32	survival	survival	NOUN
fnp-5842	119	33	.	.	PUNCT
fnp-5842	120	1	however	however	ADV
fnp-5842	120	2	,	,	PUNCT
fnp-5842	120	3	it	it	PRON
fnp-5842	120	4	is	be	AUX
fnp-5842	120	5	unclear	unclear	ADJ
fnp-5842	120	6	how	how	SCONJ
fnp-5842	120	7	these	these	DET
fnp-5842	120	8	parameters	parameter	NOUN
fnp-5842	120	9	collectively	collectively	ADV
fnp-5842	120	10	influence	influence	NOUN
fnp-5842	120	11	survival	survival	NOUN
fnp-5842	120	12	.	.	PUNCT
fnp-5842	121	1	hence	hence	ADV
fnp-5842	121	2	,	,	PUNCT
fnp-5842	121	3	we	we	PRON
fnp-5842	121	4	analysed	analyse	VERB
fnp-5842	121	5	dependencies	dependency	NOUN
fnp-5842	121	6	between	between	ADP
fnp-5842	121	7	different	different	ADJ
fnp-5842	121	8	parameters	parameter	NOUN
fnp-5842	121	9	,	,	PUNCT
fnp-5842	121	10	to	to	PART
fnp-5842	121	11	define	define	VERB
fnp-5842	121	12	novel	novel	ADJ
fnp-5842	121	13	epigenetic	epigenetic	ADJ
fnp-5842	121	14	,	,	PUNCT
fnp-5842	121	15	clinically	clinically	ADV
fnp-5842	121	16	meaningful	meaningful	ADJ
fnp-5842	121	17	subgroups	subgroup	NOUN
fnp-5842	121	18	of	of	ADP
fnp-5842	121	19	dmgs	dmgs	NOUN
fnp-5842	121	20	.	.	PUNCT
fnp-5842	122	1	we	we	PRON
fnp-5842	122	2	collected	collect	VERB
fnp-5842	122	3	a	a	DET
fnp-5842	122	4	cohort	cohort	NOUN
fnp-5842	122	5	of	of	ADP
fnp-5842	122	6	149	149	NUM
fnp-5842	122	7	h3	h3	NOUN
fnp-5842	122	8	k27m	k27m	NOUN
fnp-5842	122	9	-	-	ADJ
fnp-5842	122	10	mutant	mutant	ADJ
fnp-5842	122	11	dmgs	dmgs	NOUN
fnp-5842	122	12	,	,	PUNCT
fnp-5842	122	13	that	that	PRON
fnp-5842	122	14	could	could	AUX
fnp-5842	122	15	clearly	clearly	ADV
fnp-5842	122	16	be	be	AUX
fnp-5842	122	17	allocated	allocate	VERB
fnp-5842	122	18	to	to	ADP
fnp-5842	122	19	the	the	DET
fnp-5842	122	20	spinal	spinal	ADJ
fnp-5842	122	21	cord	cord	NOUN
fnp-5842	122	22	(	(	PUNCT
fnp-5842	122	23	n	n	CCONJ
fnp-5842	122	24	 	 	SPACE
fnp-5842	122	25	=	=	NOUN
fnp-5842	122	26	 	 	SPACE
fnp-5842	122	27	31	31	NUM
fnp-5842	122	28	;	;	PUNCT
fnp-5842	122	29	one	one	NUM
fnp-5842	122	30	patient	patient	NOUN
fnp-5842	122	31	with	with	ADP
fnp-5842	122	32	an	an	DET
fnp-5842	122	33	additional	additional	ADJ
fnp-5842	122	34	sellar	sellar	ADJ
fnp-5842	122	35	tumour	tumour	NOUN
fnp-5842	122	36	)	)	PUNCT
fnp-5842	122	37	,	,	PUNCT
fnp-5842	122	38	medulla	medulla	NOUN
fnp-5842	122	39	(	(	PUNCT
fnp-5842	122	40	n	n	CCONJ
fnp-5842	122	41	 	 	SPACE
fnp-5842	122	42	=	=	NOUN
fnp-5842	122	43	 	 	SPACE
fnp-5842	122	44	20	20	NUM
fnp-5842	122	45	)	)	PUNCT
fnp-5842	122	46	,	,	PUNCT
fnp-5842	122	47	pons	pon	NOUN
fnp-5842	122	48	(	(	PUNCT
fnp-5842	122	49	n	n	CCONJ
fnp-5842	122	50	 	 	SPACE
fnp-5842	122	51	=	=	NOUN
fnp-5842	122	52	 	 	SPACE
fnp-5842	122	53	64	64	NUM
fnp-5842	122	54	)	)	PUNCT
fnp-5842	122	55	or	or	CCONJ
fnp-5842	122	56	thalamus	thalamus	NOUN
fnp-5842	122	57	(	(	PUNCT
fnp-5842	122	58	n	n	CCONJ
fnp-5842	122	59	 	 	SPACE
fnp-5842	122	60	=	=	NOUN
fnp-5842	122	61	 	 	SPACE
fnp-5842	122	62	33	33	NUM
fnp-5842	122	63	)	)	PUNCT
fnp-5842	122	64	,	,	PUNCT
fnp-5842	122	65	including	include	VERB
fnp-5842	122	66	published	publish	VERB
fnp-5842	122	67	data	datum	NOUN
fnp-5842	122	68	.	.	PUNCT
fnp-5842	123	1	we	we	PRON
fnp-5842	123	2	then	then	ADV
fnp-5842	123	3	performed	perform	VERB
fnp-5842	123	4	dna	dna	PROPN
fnp-5842	123	5	methylation	methylation	NOUN
fnp-5842	123	6	profiling	profiling	NOUN
fnp-5842	123	7	and	and	CCONJ
fnp-5842	123	8	,	,	PUNCT
fnp-5842	123	9	for	for	ADP
fnp-5842	123	10	a	a	DET
fnp-5842	123	11	subset	subset	NOUN
fnp-5842	123	12	,	,	PUNCT
fnp-5842	123	13	dna	dna	NOUN
fnp-5842	123	14	sequencing	sequencing	NOUN
fnp-5842	123	15	and	and	CCONJ
fnp-5842	123	16	survival	survival	NOUN
fnp-5842	123	17	analyses	analysis	NOUN
fnp-5842	123	18	.	.	PUNCT
fnp-5842	124	1	unsupervised	unsupervised	ADJ
fnp-5842	124	2	hierarchical	hierarchical	ADJ
fnp-5842	124	3	clustering	clustering	NOUN
fnp-5842	124	4	of	of	ADP
fnp-5842	124	5	dna	dna	PROPN
fnp-5842	124	6	methylation	methylation	NOUN
fnp-5842	124	7	data	datum	NOUN
fnp-5842	124	8	indicated	indicate	VERB
fnp-5842	124	9	two	two	NUM
fnp-5842	124	10	clusters	cluster	NOUN
fnp-5842	124	11	of	of	ADP
fnp-5842	124	12	dmgs	dmgs	NOUN
fnp-5842	124	13	,	,	PUNCT
fnp-5842	124	14	i.e.	i.e.	X
fnp-5842	124	15	subtypes	subtype	NOUN
fnp-5842	124	16	dmg	dmg	VERB
fnp-5842	124	17	-	-	PUNCT
fnp-5842	124	18	a	a	PRON
fnp-5842	124	19	and	and	CCONJ
fnp-5842	124	20	dmg	dmg	PROPN
fnp-5842	124	21	-	-	PUNCT
fnp-5842	124	22	b.	b.	NOUN
fnp-5842	124	23	these	these	DET
fnp-5842	124	24	subtypes	subtype	NOUN
fnp-5842	124	25	differed	differ	VERB
fnp-5842	124	26	in	in	ADP
fnp-5842	124	27	mutational	mutational	ADJ
fnp-5842	124	28	spectrum	spectrum	NOUN
fnp-5842	124	29	,	,	PUNCT
fnp-5842	124	30	localisation	localisation	NOUN
fnp-5842	124	31	,	,	PUNCT
fnp-5842	124	32	age	age	NOUN
fnp-5842	124	33	at	at	ADP
fnp-5842	124	34	diagnosis	diagnosis	NOUN
fnp-5842	124	35	and	and	CCONJ
fnp-5842	124	36	overall	overall	ADJ
fnp-5842	124	37	survival	survival	NOUN
fnp-5842	124	38	.	.	PUNCT
fnp-5842	125	1	dmg	dmg	VERB
fnp-5842	125	2	-	-	PUNCT
fnp-5842	125	3	a	a	NOUN
fnp-5842	125	4	was	be	AUX
fnp-5842	125	5	enriched	enrich	VERB
fnp-5842	125	6	for	for	ADP
fnp-5842	125	7	mapk	mapk	NOUN
fnp-5842	125	8	-	-	PUNCT
fnp-5842	125	9	associated	associate	VERB
fnp-5842	125	10	mutations	mutation	NOUN
fnp-5842	125	11	,	,	PUNCT
fnp-5842	125	12	medullary	medullary	ADJ
fnp-5842	125	13	localisation	localisation	NOUN
fnp-5842	125	14	and	and	CCONJ
fnp-5842	125	15	adult	adult	NOUN
fnp-5842	125	16	age	age	NOUN
fnp-5842	125	17	.	.	PUNCT
fnp-5842	126	1	13	13	NUM
fnp-5842	126	2	 	 	SPACE
fnp-5842	126	3	%	%	NOUN
fnp-5842	126	4	had	have	VERB
fnp-5842	126	5	a	a	DET
fnp-5842	126	6	methylated	methylate	VERB
fnp-5842	126	7	mgmt	mgmt	NOUN
fnp-5842	126	8	promoter	promoter	NOUN
fnp-5842	126	9	.	.	PUNCT
fnp-5842	127	1	contrarily	contrarily	ADV
fnp-5842	127	2	,	,	PUNCT
fnp-5842	127	3	dmg	dmg	PROPN
fnp-5842	127	4	-	-	PUNCT
fnp-5842	127	5	b	b	NOUN
fnp-5842	127	6	was	be	AUX
fnp-5842	127	7	enriched	enrich	VERB
fnp-5842	127	8	for	for	ADP
fnp-5842	127	9	tp53	tp53	PROPN
fnp-5842	127	10	-	-	PUNCT
fnp-5842	127	11	mutations	mutation	NOUN
fnp-5842	127	12	,	,	PUNCT
fnp-5842	127	13	pdgfra	pdgfra	NOUN
fnp-5842	127	14	-	-	PUNCT
fnp-5842	127	15	amplifications	amplification	NOUN
fnp-5842	127	16	,	,	PUNCT
fnp-5842	127	17	pontine	pontine	ADJ
fnp-5842	127	18	localisation	localisation	NOUN
fnp-5842	127	19	and	and	CCONJ
fnp-5842	127	20	paediatric	paediatric	ADJ
fnp-5842	127	21	patients	patient	NOUN
fnp-5842	127	22	.	.	PUNCT
fnp-5842	128	1	in	in	ADP
fnp-5842	128	2	univariate	univariate	ADJ
fnp-5842	128	3	analyses	analysis	NOUN
fnp-5842	128	4	,	,	PUNCT
fnp-5842	128	5	the	the	DET
fnp-5842	128	6	features	feature	NOUN
fnp-5842	128	7	enriched	enrich	VERB
fnp-5842	128	8	in	in	ADP
fnp-5842	128	9	dmg	dmg	NOUN
fnp-5842	128	10	-	-	PUNCT
fnp-5842	128	11	b	b	NOUN
fnp-5842	128	12	were	be	AUX
fnp-5842	128	13	associated	associate	VERB
fnp-5842	128	14	with	with	ADP
fnp-5842	128	15	a	a	DET
fnp-5842	128	16	poorer	poor	ADJ
fnp-5842	128	17	survival	survival	NOUN
fnp-5842	128	18	.	.	PUNCT
fnp-5842	129	1	however	however	ADV
fnp-5842	129	2	,	,	PUNCT
fnp-5842	129	3	these	these	DET
fnp-5842	129	4	parameters	parameter	NOUN
fnp-5842	129	5	were	be	AUX
fnp-5842	129	6	dependent	dependent	ADJ
fnp-5842	129	7	on	on	ADP
fnp-5842	129	8	the	the	DET
fnp-5842	129	9	cluster	cluster	NOUN
fnp-5842	129	10	attribution	attribution	NOUN
fnp-5842	129	11	,	,	PUNCT
fnp-5842	129	12	which	which	PRON
fnp-5842	129	13	had	have	VERB
fnp-5842	129	14	the	the	DET
fnp-5842	129	15	largest	large	ADJ
fnp-5842	129	16	effect	effect	NOUN
fnp-5842	129	17	on	on	ADP
fnp-5842	129	18	survival	survival	NOUN
fnp-5842	129	19	:	:	PUNCT
fnp-5842	129	20	dmg	dmg	AUX
fnp-5842	129	21	-	-	PUNCT
fnp-5842	129	22	a	a	PRON
fnp-5842	129	23	had	have	VERB
fnp-5842	129	24	a	a	DET
fnp-5842	129	25	significantly	significantly	ADV
fnp-5842	129	26	better	well	ADJ
fnp-5842	129	27	survival	survival	NOUN
fnp-5842	129	28	compared	compare	VERB
fnp-5842	129	29	to	to	ADP
fnp-5842	129	30	dmg	dmg	VERB
fnp-5842	129	31	-	-	PUNCT
fnp-5842	129	32	b.	b.	NOUN
fnp-5842	129	33	hence	hence	ADV
fnp-5842	129	34	,	,	PUNCT
fnp-5842	129	35	the	the	DET
fnp-5842	129	36	subtype	subtype	NOUN
fnp-5842	129	37	attribution	attribution	NOUN
fnp-5842	129	38	based	base	VERB
fnp-5842	129	39	on	on	ADP
fnp-5842	129	40	two	two	NUM
fnp-5842	129	41	methylation	methylation	NOUN
fnp-5842	129	42	clusters	cluster	NOUN
fnp-5842	129	43	is	be	AUX
fnp-5842	129	44	best	well	ADV
fnp-5842	129	45	suited	suited	ADJ
fnp-5842	129	46	to	to	PART
fnp-5842	129	47	predict	predict	VERB
fnp-5842	129	48	survival	survival	NOUN
fnp-5842	129	49	as	as	SCONJ
fnp-5842	129	50	it	it	PRON
fnp-5842	129	51	integrates	integrate	VERB
fnp-5842	129	52	different	different	ADJ
fnp-5842	129	53	molecular	molecular	ADJ
fnp-5842	129	54	and	and	CCONJ
fnp-5842	129	55	clinical	clinical	ADJ
fnp-5842	129	56	parameters	parameter	NOUN
fnp-5842	129	57	.	.	PUNCT
fnp-5842	130	1	p09	p09	PROPN
fnp-5842	130	2	free	free	ADJ
fnp-5842	130	3	neuropathol	neuropathol	NOUN
fnp-5842	130	4	5:19:19	5:19:19	NUM
fnp-5842	130	5	spatial	spatial	ADJ
fnp-5842	130	6	multiomics	multiomics	NOUN
fnp-5842	130	7	profiling	profiling	NOUN
fnp-5842	130	8	reveals	reveal	VERB
fnp-5842	130	9	heterogeneity	heterogeneity	NOUN
fnp-5842	130	10	of	of	ADP
fnp-5842	130	11	b	b	NOUN
fnp-5842	130	12	:	:	PUNCT
fnp-5842	130	13	t	t	NOUN
fnp-5842	130	14	cell	cell	NOUN
fnp-5842	130	15	interactions	interaction	NOUN
fnp-5842	130	16	and	and	CCONJ
fnp-5842	130	17	plasma	plasma	NOUN
fnp-5842	130	18	cell	cell	NOUN
fnp-5842	130	19	formation	formation	NOUN
fnp-5842	130	20	in	in	ADP
fnp-5842	130	21	tertiary	tertiary	ADJ
fnp-5842	130	22	lymphoid	lymphoid	NOUN
fnp-5842	130	23	structures	structure	NOUN
fnp-5842	130	24	in	in	ADP
fnp-5842	130	25	human	human	ADJ
fnp-5842	130	26	gliomas	glioma	NOUN
fnp-5842	130	27	pinar	pinar	PROPN
fnp-5842	130	28	cakmak1,2	cakmak1,2	PROPN
fnp-5842	130	29	,	,	PUNCT
fnp-5842	130	30	*	*	PROPN
fnp-5842	130	31	,	,	PUNCT
fnp-5842	130	32	jennifer	jennifer	PROPN
fnp-5842	130	33	h.	h.	PROPN
fnp-5842	130	34	lun1,2	lun1,2	PROPN
fnp-5842	130	35	,	,	PUNCT
fnp-5842	130	36	*	*	PUNCT
fnp-5842	130	37	,	,	PUNCT
fnp-5842	130	38	aakanksha	aakanksha	PROPN
fnp-5842	130	39	singh1,2,3	singh1,2,3	PROPN
fnp-5842	130	40	,	,	PUNCT
fnp-5842	130	41	*	*	PUNCT
fnp-5842	130	42	,	,	PUNCT
fnp-5842	130	43	jadranka	jadranka	PROPN
fnp-5842	130	44	macas1,2	macas1,2	PROPN
fnp-5842	130	45	,	,	PUNCT
fnp-5842	130	46	*	*	PROPN
fnp-5842	130	47	,	,	PUNCT
fnp-5842	130	48	michael	michael	PROPN
fnp-5842	130	49	c.	c.	PROPN
fnp-5842	130	50	burger2,3,4	burger2,3,4	PROPN
fnp-5842	130	51	,	,	PUNCT
fnp-5842	130	52	lucie	lucie	PROPN
fnp-5842	130	53	marie	marie	PROPN
fnp-5842	130	54	hasse1,2,3	hasse1,2,3	PROPN
fnp-5842	130	55	,	,	PUNCT
fnp-5842	130	56	elke	elke	NOUN
fnp-5842	130	57	hattingen2,3,5,6	hattingen2,3,5,6	NOUN
fnp-5842	130	58	,	,	PUNCT
fnp-5842	130	59	miriam	miriam	PROPN
fnp-5842	130	60	köhler1	köhler1	PROPN
fnp-5842	130	61	,	,	PUNCT
fnp-5842	130	62	jonathan	jonathan	PROPN
fnp-5842	130	63	schupp1,2	schupp1,2	PROPN
fnp-5842	130	64	,	,	PUNCT
fnp-5842	130	65	tatjana	tatjana	PROPN
fnp-5842	130	66	starzetz1	starzetz1	PROPN
fnp-5842	130	67	,	,	PUNCT
fnp-5842	130	68	eike	eike	ADJ
fnp-5842	130	69	steidl5	steidl5	PROPN
fnp-5842	130	70	,	,	PUNCT
fnp-5842	130	71	karl	karl	PROPN
fnp-5842	130	72	h.	h.	PROPN
fnp-5842	130	73	plate1,2,3,6,ƚ	plate1,2,3,6,ƚ	PROPN
fnp-5842	130	74	,	,	PUNCT
fnp-5842	130	75	yvonne	yvonne	PROPN
fnp-5842	130	76	reiss1,2,6,ƚ	reiss1,2,6,ƚ	PROPN
fnp-5842	130	77	,	,	PUNCT
fnp-5842	130	78	katharina	katharina	PROPN
fnp-5842	130	79	imkeller1,2,3,ƚ	imkeller1,2,3,ƚ	PROPN
fnp-5842	130	80	1	1	NUM
fnp-5842	130	81	institute	institute	PROPN
fnp-5842	130	82	of	of	ADP
fnp-5842	130	83	neurology	neurology	NOUN
fnp-5842	130	84	(	(	PUNCT
fnp-5842	130	85	edinger	edinger	PROPN
fnp-5842	130	86	institute	institute	PROPN
fnp-5842	130	87	)	)	PUNCT
fnp-5842	130	88	,	,	PUNCT
fnp-5842	130	89	university	university	NOUN
fnp-5842	130	90	hospital	hospital	NOUN
fnp-5842	130	91	,	,	PUNCT
fnp-5842	130	92	goethe	goethe	PROPN
fnp-5842	130	93	university	university	PROPN
fnp-5842	130	94	,	,	PUNCT
fnp-5842	130	95	frankfurt	frankfurt	PROPN
fnp-5842	130	96	,	,	PUNCT
fnp-5842	130	97	germany	germany	PROPN
fnp-5842	130	98	2	2	NUM
fnp-5842	130	99	frankfurt	frankfurt	PROPN
fnp-5842	130	100	cancer	cancer	PROPN
fnp-5842	130	101	institute	institute	PROPN
fnp-5842	130	102	(	(	PUNCT
fnp-5842	130	103	fci	fci	PROPN
fnp-5842	130	104	)	)	PUNCT
fnp-5842	130	105	,	,	PUNCT
fnp-5842	130	106	frankfurt	frankfurt	PROPN
fnp-5842	130	107	,	,	PUNCT
fnp-5842	130	108	germany	germany	PROPN
fnp-5842	130	109	3	3	NUM
fnp-5842	130	110	university	university	NOUN
fnp-5842	130	111	cancer	cancer	NOUN
fnp-5842	130	112	center	center	NOUN
fnp-5842	130	113	(	(	PUNCT
fnp-5842	130	114	uct	uct	PROPN
fnp-5842	130	115	)	)	PUNCT
fnp-5842	130	116	,	,	PUNCT
fnp-5842	130	117	frankfurt	frankfurt	PROPN
fnp-5842	130	118	,	,	PUNCT
fnp-5842	130	119	germany	germany	PROPN
fnp-5842	130	120	4	4	NUM
fnp-5842	130	121	dr	dr	PROPN
fnp-5842	130	122	.	.	PROPN
fnp-5842	130	123	senckenberg	senckenberg	PROPN
fnp-5842	130	124	institute	institute	PROPN
fnp-5842	130	125	of	of	ADP
fnp-5842	130	126	neurooncology	neurooncology	PROPN
fnp-5842	130	127	,	,	PUNCT
fnp-5842	130	128	university	university	NOUN
fnp-5842	130	129	hospital	hospital	NOUN
fnp-5842	130	130	,	,	PUNCT
fnp-5842	130	131	goethe	goethe	PROPN
fnp-5842	130	132	university	university	PROPN
fnp-5842	130	133	,	,	PUNCT
fnp-5842	130	134	frankfurt	frankfurt	PROPN
fnp-5842	130	135	,	,	PUNCT
fnp-5842	130	136	germany	germany	PROPN
fnp-5842	130	137	5	5	NUM
fnp-5842	130	138	institute	institute	PROPN
fnp-5842	130	139	of	of	ADP
fnp-5842	130	140	neuroradiology	neuroradiology	NOUN
fnp-5842	130	141	,	,	PUNCT
fnp-5842	130	142	university	university	NOUN
fnp-5842	130	143	hospital	hospital	NOUN
fnp-5842	130	144	,	,	PUNCT
fnp-5842	130	145	goethe	goethe	PROPN
fnp-5842	130	146	university	university	PROPN
fnp-5842	130	147	,	,	PUNCT
fnp-5842	130	148	frankfurt	frankfurt	PROPN
fnp-5842	130	149	,	,	PUNCT
fnp-5842	130	150	germany	germany	PROPN
fnp-5842	130	151	6	6	NUM
fnp-5842	130	152	german	german	ADJ
fnp-5842	130	153	cancer	cancer	NOUN
fnp-5842	130	154	consortium	consortium	NOUN
fnp-5842	130	155	(	(	PUNCT
fnp-5842	130	156	dktk	dktk	NOUN
fnp-5842	130	157	)	)	PUNCT
fnp-5842	130	158	,	,	PUNCT
fnp-5842	130	159	partner	partner	NOUN
fnp-5842	130	160	site	site	NOUN
fnp-5842	130	161	frankfurt	frankfurt	PROPN
fnp-5842	130	162	/	/	SYM
fnp-5842	130	163	mainz	mainz	PROPN
fnp-5842	130	164	and	and	CCONJ
fnp-5842	130	165	german	german	ADJ
fnp-5842	130	166	cancer	cancer	NOUN
fnp-5842	130	167	research	research	NOUN
fnp-5842	130	168	center	center	NOUN
fnp-5842	130	169	(	(	PUNCT
fnp-5842	130	170	dkfz	dkfz	PROPN
fnp-5842	130	171	)	)	PUNCT
fnp-5842	130	172	,	,	PUNCT
fnp-5842	130	173	heidelberg	heidelberg	PROPN
fnp-5842	130	174	,	,	PUNCT
fnp-5842	130	175	germany	germany	PROPN
fnp-5842	130	176	*	*	PUNCT
fnp-5842	130	177	these	these	DET
fnp-5842	130	178	authors	author	NOUN
fnp-5842	130	179	contributed	contribute	VERB
fnp-5842	130	180	equally	equally	ADV
fnp-5842	130	181	ƚ	ƚ	ADP
fnp-5842	130	182	these	these	DET
fnp-5842	130	183	authors	author	NOUN
fnp-5842	130	184	contributed	contribute	VERB
fnp-5842	130	185	equally	equally	ADV
fnp-5842	130	186	adult	adult	NOUN
fnp-5842	130	187	-	-	PUNCT
fnp-5842	130	188	type	type	NOUN
fnp-5842	130	189	diffuse	diffuse	NOUN
fnp-5842	130	190	gliomas	glioma	NOUN
fnp-5842	130	191	,	,	PUNCT
fnp-5842	130	192	the	the	DET
fnp-5842	130	193	most	most	ADV
fnp-5842	130	194	common	common	ADJ
fnp-5842	130	195	primary	primary	ADJ
fnp-5842	130	196	brain	brain	NOUN
fnp-5842	130	197	tumors	tumor	NOUN
fnp-5842	130	198	,	,	PUNCT
fnp-5842	130	199	remain	remain	VERB
fnp-5842	130	200	a	a	DET
fnp-5842	130	201	clinical	clinical	ADJ
fnp-5842	130	202	challenge	challenge	NOUN
fnp-5842	130	203	in	in	ADP
fnp-5842	130	204	oncology	oncology	NOUN
fnp-5842	130	205	with	with	ADP
fnp-5842	130	206	limited	limited	ADJ
fnp-5842	130	207	treatment	treatment	NOUN
fnp-5842	130	208	options	option	NOUN
fnp-5842	130	209	,	,	PUNCT
fnp-5842	130	210	restricted	restrict	VERB
fnp-5842	130	211	anti	anti	ADJ
fnp-5842	130	212	-	-	ADJ
fnp-5842	130	213	tumor	tumor	ADJ
fnp-5842	130	214	immune	immune	ADJ
fnp-5842	130	215	response	response	NOUN
fnp-5842	130	216	and	and	CCONJ
fnp-5842	130	217	dismal	dismal	ADJ
fnp-5842	130	218	patient	patient	ADJ
fnp-5842	130	219	prognosis	prognosis	NOUN
fnp-5842	130	220	.	.	PUNCT
fnp-5842	131	1	despite	despite	SCONJ
fnp-5842	131	2	their	their	PRON
fnp-5842	131	3	immunosuppressive	immunosuppressive	ADJ
fnp-5842	131	4	microenvironment	microenvironment	NOUN
fnp-5842	131	5	,	,	PUNCT
fnp-5842	131	6	the	the	DET
fnp-5842	131	7	formation	formation	NOUN
fnp-5842	131	8	of	of	ADP
fnp-5842	131	9	lymphoid	lymphoid	ADJ
fnp-5842	131	10	aggregates	aggregate	NOUN
fnp-5842	131	11	containing	contain	VERB
fnp-5842	131	12	adaptive	adaptive	ADJ
fnp-5842	131	13	immune	immune	ADJ
fnp-5842	131	14	cells	cell	NOUN
fnp-5842	131	15	has	have	AUX
fnp-5842	131	16	been	be	AUX
fnp-5842	131	17	reported	report	VERB
fnp-5842	131	18	in	in	ADP
fnp-5842	131	19	gliomas	glioma	NOUN
fnp-5842	131	20	.	.	PUNCT
fnp-5842	132	1	however	however	ADV
fnp-5842	132	2	,	,	PUNCT
fnp-5842	132	3	the	the	DET
fnp-5842	132	4	cellular	cellular	ADJ
fnp-5842	132	5	composition	composition	NOUN
fnp-5842	132	6	,	,	PUNCT
fnp-5842	132	7	immunological	immunological	ADJ
fnp-5842	132	8	function	function	NOUN
fnp-5842	132	9	and	and	CCONJ
fnp-5842	132	10	relevance	relevance	NOUN
fnp-5842	132	11	of	of	ADP
fnp-5842	132	12	lymphoid	lymphoid	ADJ
fnp-5842	132	13	aggregates	aggregate	NOUN
fnp-5842	132	14	for	for	ADP
fnp-5842	132	15	adaptive	adaptive	ADJ
fnp-5842	132	16	anti	anti	ADJ
fnp-5842	132	17	-	-	ADJ
fnp-5842	132	18	glioma	glioma	ADJ
fnp-5842	132	19	immunity	immunity	NOUN
fnp-5842	132	20	is	be	AUX
fnp-5842	132	21	not	not	PART
fnp-5842	132	22	well	well	ADV
fnp-5842	132	23	understood	understand	VERB
fnp-5842	132	24	.	.	PUNCT
fnp-5842	133	1	therefore	therefore	ADV
fnp-5842	133	2	,	,	PUNCT
fnp-5842	133	3	we	we	PRON
fnp-5842	133	4	performed	perform	VERB
fnp-5842	133	5	a	a	DET
fnp-5842	133	6	comprehensive	comprehensive	ADJ
fnp-5842	133	7	,	,	PUNCT
fnp-5842	133	8	unbiased	unbiased	ADJ
fnp-5842	133	9	analysis	analysis	NOUN
fnp-5842	133	10	of	of	ADP
fnp-5842	133	11	lymphoid	lymphoid	ADJ
fnp-5842	133	12	aggregation	aggregation	NOUN
fnp-5842	133	13	in	in	ADP
fnp-5842	133	14	642	642	NUM
fnp-5842	133	15	adult	adult	NOUN
fnp-5842	133	16	-	-	PUNCT
fnp-5842	133	17	type	type	NOUN
fnp-5842	133	18	diffuse	diffuse	NOUN
fnp-5842	133	19	gliomas	glioma	NOUN
fnp-5842	133	20	using	use	VERB
fnp-5842	133	21	a	a	DET
fnp-5842	133	22	multi	multi	ADJ
fnp-5842	133	23	-	-	ADJ
fnp-5842	133	24	modal	modal	ADJ
fnp-5842	133	25	approach	approach	NOUN
fnp-5842	133	26	;	;	PUNCT
fnp-5842	133	27	combining	combine	VERB
fnp-5842	133	28	dna	dna	PROPN
fnp-5842	133	29	methylation	methylation	NOUN
fnp-5842	133	30	,	,	PUNCT
fnp-5842	133	31	rna	rna	NOUN
fnp-5842	133	32	sequencing	sequencing	NOUN
fnp-5842	133	33	with	with	ADP
fnp-5842	133	34	spatial	spatial	ADJ
fnp-5842	133	35	transcriptome	transcriptome	NOUN
fnp-5842	133	36	and	and	CCONJ
fnp-5842	133	37	proteome	proteome	ADJ
fnp-5842	133	38	profiling	profiling	NOUN
fnp-5842	133	39	.	.	PUNCT
fnp-5842	134	1	overall	overall	ADJ
fnp-5842	134	2	,	,	PUNCT
fnp-5842	134	3	b	b	NOUN
fnp-5842	134	4	cell	cell	NOUN
fnp-5842	134	5	aggregates	aggregate	NOUN
fnp-5842	134	6	and	and	CCONJ
fnp-5842	134	7	tertiary	tertiary	ADJ
fnp-5842	134	8	lymphoid	lymphoid	NOUN
fnp-5842	134	9	structures	structure	NOUN
fnp-5842	134	10	(	(	PUNCT
fnp-5842	134	11	tls	tls	PROPN
fnp-5842	134	12	)	)	PUNCT
fnp-5842	134	13	were	be	AUX
fnp-5842	134	14	observed	observe	VERB
fnp-5842	134	15	in	in	ADP
fnp-5842	134	16	15	15	NUM
fnp-5842	134	17	 	 	SPACE
fnp-5842	134	18	%	%	NOUN
fnp-5842	134	19	of	of	ADP
fnp-5842	134	20	tumors	tumor	NOUN
fnp-5842	134	21	and	and	CCONJ
fnp-5842	134	22	associated	associate	VERB
fnp-5842	134	23	with	with	ADP
fnp-5842	134	24	an	an	DET
fnp-5842	134	25	improved	improved	ADJ
fnp-5842	134	26	overall	overall	ADJ
fnp-5842	134	27	survival	survival	NOUN
fnp-5842	134	28	.	.	PUNCT
fnp-5842	135	1	gliomas	glioma	NOUN
fnp-5842	135	2	containing	contain	VERB
fnp-5842	135	3	tls	tls	PROPN
fnp-5842	135	4	displayed	display	VERB
fnp-5842	135	5	a	a	DET
fnp-5842	135	6	remodeled	remodeled	ADJ
fnp-5842	135	7	perivascular	perivascular	ADJ
fnp-5842	135	8	space	space	NOUN
fnp-5842	135	9	,	,	PUNCT
fnp-5842	135	10	characterized	characterize	VERB
fnp-5842	135	11	by	by	ADP
fnp-5842	135	12	transcriptional	transcriptional	ADJ
fnp-5842	135	13	upregulation	upregulation	NOUN
fnp-5842	135	14	and	and	CCONJ
fnp-5842	135	15	spatial	spatial	ADJ
fnp-5842	135	16	redistribution	redistribution	NOUN
fnp-5842	135	17	of	of	ADP
fnp-5842	135	18	collagens	collagen	NOUN
fnp-5842	135	19	associated	associate	VERB
fnp-5842	135	20	with	with	ADP
fnp-5842	135	21	barrier	barrier	NOUN
fnp-5842	135	22	functions	function	NOUN
fnp-5842	135	23	.	.	PUNCT
fnp-5842	136	1	spatial	spatial	ADJ
fnp-5842	136	2	transcriptome	transcriptome	NOUN
fnp-5842	136	3	and	and	CCONJ
fnp-5842	136	4	proteome	proteome	ADJ
fnp-5842	136	5	profiling	profiling	NOUN
fnp-5842	136	6	revealed	reveal	VERB
fnp-5842	136	7	heterogeneous	heterogeneous	ADJ
fnp-5842	136	8	b	b	NOUN
fnp-5842	136	9	:	:	PUNCT
fnp-5842	136	10	t	t	NOUN
fnp-5842	136	11	cell	cell	NOUN
fnp-5842	136	12	interactions	interaction	NOUN
fnp-5842	136	13	that	that	PRON
fnp-5842	136	14	were	be	AUX
fnp-5842	136	15	associated	associate	VERB
fnp-5842	136	16	with	with	ADP
fnp-5842	136	17	elevated	elevated	ADJ
fnp-5842	136	18	cd8	cd8	PROPN
fnp-5842	136	19	t	t	PROPN
fnp-5842	136	20	-	-	PUNCT
fnp-5842	136	21	cell	cell	NOUN
fnp-5842	136	22	numbers	number	NOUN
fnp-5842	136	23	and	and	CCONJ
fnp-5842	136	24	differences	difference	NOUN
fnp-5842	136	25	in	in	ADP
fnp-5842	136	26	iga	iga	PROPN
fnp-5842	136	27	and	and	CCONJ
fnp-5842	136	28	igg	igg	PROPN
fnp-5842	136	29	plasma	plasma	NOUN
fnp-5842	136	30	-	-	PUNCT
fnp-5842	136	31	cell	cell	NOUN
fnp-5842	136	32	forming	form	VERB
fnp-5842	136	33	capacity	capacity	NOUN
fnp-5842	136	34	,	,	PUNCT
fnp-5842	136	35	suggestive	suggestive	ADJ
fnp-5842	136	36	of	of	ADP
fnp-5842	136	37	dynamic	dynamic	ADJ
fnp-5842	136	38	adaptive	adaptive	ADJ
fnp-5842	136	39	immune	immune	ADJ
fnp-5842	136	40	responses	response	NOUN
fnp-5842	136	41	.	.	PUNCT
fnp-5842	137	1	p10	p10	NOUN
fnp-5842	137	2	free	free	ADJ
fnp-5842	137	3	neuropathol	neuropathol	NOUN
fnp-5842	137	4	5:19:20	5:19:20	NUM
fnp-5842	137	5	digital	digital	ADJ
fnp-5842	137	6	biomarkers	biomarker	NOUN
fnp-5842	137	7	for	for	ADP
fnp-5842	137	8	an	an	DET
fnp-5842	137	9	improved	improve	VERB
fnp-5842	137	10	clinical	clinical	ADJ
fnp-5842	137	11	stratification	stratification	NOUN
fnp-5842	137	12	of	of	ADP
fnp-5842	137	13	meningioma	meningioma	NOUN
fnp-5842	137	14	patients	patient	NOUN
fnp-5842	137	15	moritz	moritz	PROPN
fnp-5842	137	16	armbrust1	armbrust1	PROPN
fnp-5842	137	17	,	,	PUNCT
fnp-5842	137	18	eike	eike	ADJ
fnp-5842	137	19	steidl2,3,4	steidl2,3,4	PROPN
fnp-5842	137	20	,	,	PUNCT
fnp-5842	137	21	nadine	nadine	PROPN
fnp-5842	137	22	flinner2,5,6,7	flinner2,5,6,7	PROPN
fnp-5842	137	23	,	,	PUNCT
fnp-5842	137	24	lina	lina	PROPN
fnp-5842	137	25	-	-	PROPN
fnp-5842	137	26	elisabeth	elisabeth	PROPN
fnp-5842	137	27	qasem2,8	qasem2,8	PROPN
fnp-5842	137	28	,	,	PUNCT
fnp-5842	137	29	ali	ali	PROPN
fnp-5842	137	30	al	al	PROPN
fnp-5842	137	31	-	-	PUNCT
fnp-5842	137	32	hilou8	hilou8	PROPN
fnp-5842	137	33	,	,	PUNCT
fnp-5842	137	34	florian	florian	ADJ
fnp-5842	137	35	buettner4,7,9,10	buettner4,7,9,10	PROPN
fnp-5842	137	36	,	,	PUNCT
fnp-5842	137	37	karl	karl	PROPN
fnp-5842	137	38	h.	h.	PROPN
fnp-5842	137	39	plate1,2,4,7	plate1,2,4,7	PROPN
fnp-5842	137	40	,	,	PUNCT
fnp-5842	137	41	marcus	marcus	PROPN
fnp-5842	137	42	czabanka2,4,7,8	czabanka2,4,7,8	PROPN
fnp-5842	137	43	,	,	PUNCT
fnp-5842	137	44	katharina	katharina	PROPN
fnp-5842	137	45	j.	j.	PROPN
fnp-5842	137	46	weber1,2,4,7	weber1,2,4,7	PROPN
fnp-5842	137	47	1	1	NUM
fnp-5842	137	48	neurological	neurological	ADJ
fnp-5842	137	49	institute	institute	NOUN
fnp-5842	137	50	(	(	PUNCT
fnp-5842	137	51	edinger	edinger	PROPN
fnp-5842	137	52	institute	institute	PROPN
fnp-5842	137	53	)	)	PUNCT
fnp-5842	137	54	,	,	PUNCT
fnp-5842	137	55	university	university	NOUN
fnp-5842	137	56	hospital	hospital	NOUN
fnp-5842	137	57	,	,	PUNCT
fnp-5842	137	58	goethe	goethe	PROPN
fnp-5842	137	59	university	university	PROPN
fnp-5842	137	60	,	,	PUNCT
fnp-5842	137	61	frankfurt	frankfurt	PROPN
fnp-5842	137	62	am	be	AUX
fnp-5842	137	63	main	main	ADJ
fnp-5842	137	64	,	,	PUNCT
fnp-5842	137	65	germany	germany	PROPN
fnp-5842	137	66	2	2	NUM
fnp-5842	137	67	university	university	NOUN
fnp-5842	137	68	cancer	cancer	NOUN
fnp-5842	137	69	center	center	NOUN
fnp-5842	137	70	(	(	PUNCT
fnp-5842	137	71	uct	uct	PROPN
fnp-5842	137	72	)	)	PUNCT
fnp-5842	137	73	frankfurt	frankfurt	PROPN
fnp-5842	137	74	-	-	PUNCT
fnp-5842	137	75	marburg	marburg	PROPN
fnp-5842	137	76	,	,	PUNCT
fnp-5842	137	77	university	university	NOUN
fnp-5842	137	78	hospital	hospital	NOUN
fnp-5842	137	79	,	,	PUNCT
fnp-5842	137	80	goethe	goethe	PROPN
fnp-5842	137	81	university	university	PROPN
fnp-5842	137	82	,	,	PUNCT
fnp-5842	137	83	frankfurt	frankfurt	PROPN
fnp-5842	137	84	am	be	AUX
fnp-5842	137	85	main	main	ADJ
fnp-5842	137	86	,	,	PUNCT
fnp-5842	137	87	germany	germany	PROPN
fnp-5842	137	88	3	3	NUM
fnp-5842	137	89	institute	institute	PROPN
fnp-5842	137	90	of	of	ADP
fnp-5842	137	91	neuroradiology	neuroradiology	NOUN
fnp-5842	137	92	,	,	PUNCT
fnp-5842	137	93	university	university	NOUN
fnp-5842	137	94	hospital	hospital	NOUN
fnp-5842	137	95	,	,	PUNCT
fnp-5842	137	96	goethe	goethe	PROPN
fnp-5842	137	97	university	university	PROPN
fnp-5842	137	98	,	,	PUNCT
fnp-5842	137	99	frankfurt	frankfurt	PROPN
fnp-5842	137	100	am	be	AUX
fnp-5842	137	101	main	main	ADJ
fnp-5842	137	102	,	,	PUNCT
fnp-5842	137	103	germany	germany	NOUN
fnp-5842	137	104	4	4	NUM
fnp-5842	137	105	german	german	ADJ
fnp-5842	137	106	cancer	cancer	NOUN
fnp-5842	137	107	consortium	consortium	NOUN
fnp-5842	137	108	(	(	PUNCT
fnp-5842	137	109	dktk	dktk	NOUN
fnp-5842	137	110	)	)	PUNCT
fnp-5842	137	111	,	,	PUNCT
fnp-5842	137	112	partner	partner	NOUN
fnp-5842	137	113	site	site	NOUN
fnp-5842	137	114	frankfurt	frankfurt	PROPN
fnp-5842	137	115	/	/	SYM
fnp-5842	137	116	mainz	mainz	PROPN
fnp-5842	137	117	and	and	CCONJ
fnp-5842	137	118	german	german	ADJ
fnp-5842	137	119	cancer	cancer	NOUN
fnp-5842	137	120	research	research	NOUN
fnp-5842	137	121	center	center	NOUN
fnp-5842	137	122	(	(	PUNCT
fnp-5842	137	123	dkfz	dkfz	PROPN
fnp-5842	137	124	)	)	PUNCT
fnp-5842	137	125	,	,	PUNCT
fnp-5842	137	126	heidelberg	heidelberg	PROPN
fnp-5842	137	127	,	,	PUNCT
fnp-5842	137	128	germany	germany	PROPN
fnp-5842	137	129	5	5	NUM
fnp-5842	137	130	dr	dr	PROPN
fnp-5842	137	131	.	.	PROPN
fnp-5842	137	132	senckenberg	senckenberg	PROPN
fnp-5842	137	133	institute	institute	PROPN
fnp-5842	137	134	of	of	ADP
fnp-5842	137	135	pathology	pathology	PROPN
fnp-5842	137	136	,	,	PUNCT
fnp-5842	137	137	university	university	NOUN
fnp-5842	137	138	hospital	hospital	NOUN
fnp-5842	137	139	,	,	PUNCT
fnp-5842	137	140	goethe	goethe	PROPN
fnp-5842	137	141	university	university	PROPN
fnp-5842	137	142	,	,	PUNCT
fnp-5842	137	143	frankfurt	frankfurt	PROPN
fnp-5842	137	144	am	be	AUX
fnp-5842	137	145	main	main	ADJ
fnp-5842	137	146	,	,	PUNCT
fnp-5842	137	147	germany	germany	PROPN
fnp-5842	137	148	6	6	NUM
fnp-5842	137	149	frankfurt	frankfurt	PROPN
fnp-5842	137	150	institute	institute	NOUN
fnp-5842	137	151	for	for	ADP
fnp-5842	137	152	advanced	advanced	ADJ
fnp-5842	137	153	studies	study	NOUN
fnp-5842	137	154	(	(	PUNCT
fnp-5842	137	155	fias	fias	PROPN
fnp-5842	137	156	)	)	PUNCT
fnp-5842	137	157	,	,	PUNCT
fnp-5842	137	158	frankfurt	frankfurt	PROPN
fnp-5842	137	159	am	be	AUX
fnp-5842	137	160	main	main	ADJ
fnp-5842	137	161	,	,	PUNCT
fnp-5842	137	162	germany	germany	PROPN
fnp-5842	137	163	7	7	NUM
fnp-5842	137	164	frankfurt	frankfurt	PROPN
fnp-5842	137	165	cancer	cancer	PROPN
fnp-5842	137	166	institute	institute	PROPN
fnp-5842	137	167	(	(	PUNCT
fnp-5842	137	168	fci	fci	PROPN
fnp-5842	137	169	)	)	PUNCT
fnp-5842	137	170	,	,	PUNCT
fnp-5842	137	171	goethe	goethe	PROPN
fnp-5842	137	172	university	university	PROPN
fnp-5842	137	173	,	,	PUNCT
fnp-5842	137	174	frankfurt	frankfurt	PROPN
fnp-5842	137	175	am	be	AUX
fnp-5842	137	176	main	main	ADJ
fnp-5842	137	177	,	,	PUNCT
fnp-5842	137	178	germany	germany	PROPN
fnp-5842	137	179	8	8	NUM
fnp-5842	137	180	department	department	NOUN
fnp-5842	137	181	of	of	ADP
fnp-5842	137	182	neurosurgery	neurosurgery	NOUN
fnp-5842	137	183	,	,	PUNCT
fnp-5842	137	184	university	university	NOUN
fnp-5842	137	185	hospital	hospital	NOUN
fnp-5842	137	186	,	,	PUNCT
fnp-5842	137	187	goethe	goethe	PROPN
fnp-5842	137	188	university	university	PROPN
fnp-5842	137	189	,	,	PUNCT
fnp-5842	137	190	frankfurt	frankfurt	PROPN
fnp-5842	137	191	am	be	AUX
fnp-5842	137	192	main	main	ADJ
fnp-5842	137	193	,	,	PUNCT
fnp-5842	137	194	germany	germany	PROPN
fnp-5842	137	195	9	9	NUM
fnp-5842	137	196	department	department	NOUN
fnp-5842	137	197	of	of	ADP
fnp-5842	137	198	medicine	medicine	NOUN
fnp-5842	137	199	,	,	PUNCT
fnp-5842	137	200	goethe	goethe	PROPN
fnp-5842	137	201	university	university	PROPN
fnp-5842	137	202	,	,	PUNCT
fnp-5842	137	203	frankfurt	frankfurt	PROPN
fnp-5842	137	204	am	be	AUX
fnp-5842	137	205	main	main	ADJ
fnp-5842	137	206	,	,	PUNCT
fnp-5842	137	207	germany	germany	PROPN
fnp-5842	137	208	10	10	NUM
fnp-5842	137	209	department	department	PROPN
fnp-5842	137	210	of	of	ADP
fnp-5842	137	211	informatics	informatics	PROPN
fnp-5842	137	212	,	,	PUNCT
fnp-5842	137	213	goethe	goethe	PROPN
fnp-5842	137	214	university	university	PROPN
fnp-5842	137	215	,	,	PUNCT
fnp-5842	137	216	frankfurt	frankfurt	PROPN
fnp-5842	137	217	am	be	AUX
fnp-5842	137	218	main	main	ADJ
fnp-5842	137	219	,	,	PUNCT
fnp-5842	137	220	germany	germany	NOUN
fnp-5842	137	221	introduction	introduction	NOUN
fnp-5842	137	222	:	:	PUNCT
fnp-5842	137	223	postsurgical	postsurgical	ADJ
fnp-5842	137	224	therapy	therapy	NOUN
fnp-5842	137	225	concepts	concept	NOUN
fnp-5842	137	226	in	in	ADP
fnp-5842	137	227	meningiomas	meningioma	NOUN
fnp-5842	137	228	are	be	AUX
fnp-5842	137	229	influenced	influence	VERB
fnp-5842	137	230	by	by	ADP
fnp-5842	137	231	the	the	DET
fnp-5842	137	232	world	world	PROPN
fnp-5842	137	233	health	health	NOUN
fnp-5842	137	234	organisation	organisation	NOUN
fnp-5842	137	235	(	(	PUNCT
fnp-5842	137	236	who	who	PRON
fnp-5842	137	237	)	)	PUNCT
fnp-5842	137	238	three	three	NUM
fnp-5842	137	239	-	-	PUNCT
fnp-5842	137	240	tiered	tiere	VERB
fnp-5842	137	241	histomorphological	histomorphological	NOUN
fnp-5842	137	242	grading	grading	NOUN
fnp-5842	137	243	,	,	PUNCT
fnp-5842	137	244	which	which	PRON
fnp-5842	137	245	is	be	AUX
fnp-5842	137	246	subjected	subject	VERB
fnp-5842	137	247	to	to	ADP
fnp-5842	137	248	a	a	DET
fnp-5842	137	249	high	high	ADJ
fnp-5842	137	250	interobserver	interobserver	ADJ
fnp-5842	137	251	variability	variability	NOUN
fnp-5842	137	252	and	and	CCONJ
fnp-5842	137	253	low	low	ADJ
fnp-5842	137	254	reproducibility	reproducibility	NOUN
fnp-5842	137	255	.	.	PUNCT
fnp-5842	138	1	risk	risk	NOUN
fnp-5842	138	2	-	-	PUNCT
fnp-5842	138	3	of	of	ADP
fnp-5842	138	4	-	-	PUNCT
fnp-5842	138	5	recurrence	recurrence	NOUN
fnp-5842	138	6	models	model	NOUN
fnp-5842	138	7	,	,	PUNCT
fnp-5842	138	8	integrating	integrate	VERB
fnp-5842	138	9	histology	histology	NOUN
fnp-5842	138	10	and	and	CCONJ
fnp-5842	138	11	molecular	molecular	ADJ
fnp-5842	138	12	tumor	tumor	NOUN
fnp-5842	138	13	data	datum	NOUN
fnp-5842	138	14	,	,	PUNCT
fnp-5842	138	15	have	have	AUX
fnp-5842	138	16	been	be	AUX
fnp-5842	138	17	developed	develop	VERB
fnp-5842	138	18	to	to	PART
fnp-5842	138	19	improve	improve	VERB
fnp-5842	138	20	patient	patient	ADJ
fnp-5842	138	21	stratification	stratification	NOUN
fnp-5842	138	22	.	.	PUNCT
fnp-5842	139	1	however	however	ADV
fnp-5842	139	2	,	,	PUNCT
fnp-5842	139	3	the	the	DET
fnp-5842	139	4	distinguishment	distinguishment	NOUN
fnp-5842	139	5	between	between	ADP
fnp-5842	139	6	meningioma	meningioma	NOUN
fnp-5842	139	7	patients	patient	NOUN
fnp-5842	139	8	with	with	ADP
fnp-5842	139	9	a	a	DET
fnp-5842	139	10	low	low	ADJ
fnp-5842	139	11	risk	risk	NOUN
fnp-5842	139	12	of	of	ADP
fnp-5842	139	13	recurrence	recurrence	NOUN
fnp-5842	139	14	from	from	ADP
fnp-5842	139	15	those	those	PRON
fnp-5842	139	16	with	with	ADP
fnp-5842	139	17	an	an	DET
fnp-5842	139	18	intermediate	intermediate	ADJ
fnp-5842	139	19	risk	risk	NOUN
fnp-5842	139	20	remains	remain	VERB
fnp-5842	139	21	particularly	particularly	ADV
fnp-5842	139	22	challenging	challenging	ADJ
fnp-5842	139	23	.	.	PUNCT
fnp-5842	140	1	here	here	ADV
fnp-5842	140	2	,	,	PUNCT
fnp-5842	140	3	we	we	PRON
fnp-5842	140	4	propose	propose	VERB
fnp-5842	140	5	imageand	imageand	NOUN
fnp-5842	140	6	methylome	methylome	ADV
fnp-5842	140	7	-	-	PUNCT
fnp-5842	140	8	based	base	VERB
fnp-5842	140	9	biomarkers	biomarker	NOUN
fnp-5842	140	10	for	for	ADP
fnp-5842	140	11	a	a	DET
fnp-5842	140	12	refined	refined	ADJ
fnp-5842	140	13	outcome	outcome	NOUN
fnp-5842	140	14	prognostication	prognostication	NOUN
fnp-5842	140	15	.	.	PUNCT
fnp-5842	141	1	material	material	NOUN
fnp-5842	141	2	and	and	CCONJ
fnp-5842	141	3	methods	method	NOUN
fnp-5842	141	4	:	:	PUNCT
fnp-5842	141	5	whole	whole	ADJ
fnp-5842	141	6	slide	slide	NOUN
fnp-5842	141	7	images	image	NOUN
fnp-5842	141	8	(	(	PUNCT
fnp-5842	141	9	wsi	wsi	NOUN
fnp-5842	141	10	)	)	PUNCT
fnp-5842	141	11	of	of	ADP
fnp-5842	141	12	ki67	ki67	PROPN
fnp-5842	141	13	-	-	PUNCT
fnp-5842	141	14	stained	stain	VERB
fnp-5842	141	15	meningioma	meningioma	NOUN
fnp-5842	141	16	samples	sample	NOUN
fnp-5842	141	17	were	be	AUX
fnp-5842	141	18	generated	generate	VERB
fnp-5842	141	19	and	and	CCONJ
fnp-5842	141	20	dna	dna	PROPN
fnp-5842	141	21	methylomes	methylome	NOUN
fnp-5842	141	22	were	be	AUX
fnp-5842	141	23	collected	collect	VERB
fnp-5842	141	24	(	(	PUNCT
fnp-5842	141	25	n	n	CCONJ
fnp-5842	141	26	 	 	SPACE
fnp-5842	141	27	=	=	NOUN
fnp-5842	141	28	 	 	SPACE
fnp-5842	141	29	173	173	NUM
fnp-5842	141	30	)	)	PUNCT
fnp-5842	141	31	.	.	PUNCT
fnp-5842	142	1	a	a	DET
fnp-5842	142	2	random	random	NOUN
fnp-5842	142	3	-	-	PUNCT
fnp-5842	142	4	forest	forest	NOUN
fnp-5842	142	5	based	base	VERB
fnp-5842	142	6	pixel	pixel	PROPN
fnp-5842	142	7	classifier	classifier	NOUN
fnp-5842	142	8	for	for	ADP
fnp-5842	142	9	a	a	DET
fnp-5842	142	10	machine	machine	NOUN
fnp-5842	142	11	-	-	PUNCT
fnp-5842	142	12	learning	learn	VERB
fnp-5842	142	13	based	base	VERB
fnp-5842	142	14	tumor	tumor	NOUN
fnp-5842	142	15	segmentation	segmentation	NOUN
fnp-5842	142	16	was	be	AUX
fnp-5842	142	17	generated	generate	VERB
fnp-5842	142	18	on	on	ADP
fnp-5842	142	19	training	training	NOUN
fnp-5842	142	20	images	image	NOUN
fnp-5842	142	21	(	(	PUNCT
fnp-5842	142	22	n	n	CCONJ
fnp-5842	142	23	 	 	SPACE
fnp-5842	142	24	=	=	NOUN
fnp-5842	142	25	 	 	SPACE
fnp-5842	142	26	110	110	NUM
fnp-5842	142	27	)	)	PUNCT
fnp-5842	142	28	.	.	PUNCT
fnp-5842	143	1	in	in	ADP
fnp-5842	143	2	a	a	DET
fnp-5842	143	3	scripted	script	VERB
fnp-5842	143	4	batch	batch	NOUN
fnp-5842	143	5	processing	processing	NOUN
fnp-5842	143	6	,	,	PUNCT
fnp-5842	143	7	the	the	DET
fnp-5842	143	8	ki67	ki67	PROPN
fnp-5842	143	9	marker	marker	NOUN
fnp-5842	143	10	was	be	AUX
fnp-5842	143	11	spatially	spatially	ADV
fnp-5842	143	12	quantified	quantify	VERB
fnp-5842	143	13	within	within	ADP
fnp-5842	143	14	randomly	randomly	ADV
fnp-5842	143	15	distributed	distribute	VERB
fnp-5842	143	16	,	,	PUNCT
fnp-5842	143	17	segmented	segment	VERB
fnp-5842	143	18	image	image	NOUN
fnp-5842	143	19	tiles	tile	NOUN
fnp-5842	143	20	(	(	PUNCT
fnp-5842	143	21	10	10	NUM
fnp-5842	143	22	tiles	tile	NOUN
fnp-5842	143	23	,	,	PUNCT
fnp-5842	143	24	tumor	tumor	NOUN
fnp-5842	143	25	area	area	NOUN
fnp-5842	143	26	10	10	NUM
fnp-5842	143	27	 	 	SPACE
fnp-5842	143	28	mm2	mm2	NOUN
fnp-5842	143	29	)	)	PUNCT
fnp-5842	143	30	.	.	PUNCT
fnp-5842	144	1	further	far	ADV
fnp-5842	144	2	,	,	PUNCT
fnp-5842	144	3	samples	sample	NOUN
fnp-5842	144	4	were	be	AUX
fnp-5842	144	5	epigenetically	epigenetically	ADV
fnp-5842	144	6	subcharacterized	subcharacterize	VERB
fnp-5842	144	7	by	by	ADP
fnp-5842	144	8	reference	reference	NOUN
fnp-5842	144	9	-	-	PUNCT
fnp-5842	144	10	free	free	ADJ
fnp-5842	144	11	tumor	tumor	NOUN
fnp-5842	144	12	deconvolution	deconvolution	NOUN
fnp-5842	144	13	.	.	PUNCT
fnp-5842	145	1	results	result	NOUN
fnp-5842	145	2	:	:	PUNCT
fnp-5842	145	3	the	the	DET
fnp-5842	145	4	wsi	wsi	PROPN
fnp-5842	145	5	data	data	NOUN
fnp-5842	145	6	is	be	AUX
fnp-5842	145	7	assignable	assignable	ADJ
fnp-5842	145	8	to	to	ADP
fnp-5842	145	9	methylation	methylation	NOUN
fnp-5842	145	10	subclasses	subclass	NOUN
fnp-5842	145	11	within	within	ADP
fnp-5842	145	12	the	the	DET
fnp-5842	145	13	heidelberg	heidelberg	NOUN
fnp-5842	145	14	v12.8	v12.8	PROPN
fnp-5842	145	15	brain	brain	NOUN
fnp-5842	145	16	tumor	tumor	NOUN
fnp-5842	145	17	classifier	classifier	NOUN
fnp-5842	145	18	(	(	PUNCT
fnp-5842	145	19	median	median	PROPN
fnp-5842	145	20	ki67	ki67	PROPN
fnp-5842	145	21	grouped	group	VERB
fnp-5842	145	22	subclasses	subclass	NOUN
fnp-5842	145	23	benign	benign	ADJ
fnp-5842	145	24	1	1	NUM
fnp-5842	145	25	-	-	SYM
fnp-5842	145	26	3	3	NUM
fnp-5842	145	27	and	and	CCONJ
fnp-5842	145	28	intermediate	intermediate	ADJ
fnp-5842	145	29	-	-	PUNCT
fnp-5842	145	30	a	a	NOUN
fnp-5842	145	31	 	 	SPACE
fnp-5842	145	32	=	=	NOUN
fnp-5842	145	33	 	 	SPACE
fnp-5842	145	34	5.0	5.0	NUM
fnp-5842	145	35	 	 	SPACE
fnp-5842	145	36	%	%	NOUN
fnp-5842	145	37	;	;	PUNCT
fnp-5842	145	38	median	median	PROPN
fnp-5842	145	39	ki67	ki67	PROPN
fnp-5842	145	40	grouped	group	VERB
fnp-5842	145	41	subclasses	subclass	NOUN
fnp-5842	145	42	intermediate	intermediate	ADJ
fnp-5842	145	43	-	-	PUNCT
fnp-5842	145	44	b	b	NOUN
fnp-5842	145	45	and	and	CCONJ
fnp-5842	145	46	malignant	malignant	ADJ
fnp-5842	145	47	 	 	SPACE
fnp-5842	145	48	=	=	NOUN
fnp-5842	145	49	 	 	SPACE
fnp-5842	145	50	7.0	7.0	NUM
fnp-5842	145	51	 	 	SPACE
fnp-5842	145	52	%	%	NOUN
fnp-5842	145	53	;	;	PUNCT
fnp-5842	145	54	p	p	X
fnp-5842	145	55	 	 	SPACE
fnp-5842	145	56	=	=	PRON
fnp-5842	145	57	 	 	SPACE
fnp-5842	145	58	0.0096	0.0096	NUM
fnp-5842	145	59	;	;	PUNCT
fnp-5842	145	60	mann	mann	PROPN
fnp-5842	145	61	-	-	PUNCT
fnp-5842	145	62	whitney	whitney	PROPN
fnp-5842	145	63	u	u	PROPN
fnp-5842	145	64	test	test	NOUN
fnp-5842	145	65	;	;	PUNCT
fnp-5842	145	66	n	n	CCONJ
fnp-5842	145	67	 	 	SPACE
fnp-5842	145	68	=	=	NOUN
fnp-5842	145	69	 	 	SPACE
fnp-5842	145	70	135	135	NUM
fnp-5842	145	71	)	)	PUNCT
fnp-5842	145	72	.	.	PUNCT
fnp-5842	146	1	integrated	integrate	VERB
fnp-5842	146	2	risk	risk	NOUN
fnp-5842	146	3	-	-	PUNCT
fnp-5842	146	4	of	of	ADP
fnp-5842	146	5	-	-	PUNCT
fnp-5842	146	6	recurrence	recurrence	NOUN
fnp-5842	146	7	scores	score	NOUN
fnp-5842	146	8	(	(	PUNCT
fnp-5842	146	9	ints	int	NOUN
fnp-5842	146	10	,	,	PUNCT
fnp-5842	146	11	hielscher	hielscher	NOUN
fnp-5842	146	12	et	et	PROPN
fnp-5842	146	13	al	al	PROPN
fnp-5842	146	14	.	.	PROPN
fnp-5842	146	15	,	,	PUNCT
fnp-5842	146	16	2022	2022	NUM
fnp-5842	146	17	)	)	PUNCT
fnp-5842	146	18	are	be	AUX
fnp-5842	146	19	distinguishable	distinguishable	ADJ
fnp-5842	146	20	based	base	VERB
fnp-5842	146	21	on	on	ADP
fnp-5842	146	22	proliferation	proliferation	NOUN
fnp-5842	146	23	(	(	PUNCT
fnp-5842	146	24	median	median	PROPN
fnp-5842	146	25	ki67	ki67	PROPN
fnp-5842	146	26	ints	int	NOUN
fnp-5842	146	27	low	low	ADJ
fnp-5842	146	28	 	 	SPACE
fnp-5842	146	29	=	=	NOUN
fnp-5842	146	30	 	 	SPACE
fnp-5842	146	31	4.1	4.1	NUM
fnp-5842	146	32	 	 	SPACE
fnp-5842	146	33	%	%	NOUN
fnp-5842	146	34	;	;	PUNCT
fnp-5842	146	35	median	median	PROPN
fnp-5842	146	36	ki67	ki67	PROPN
fnp-5842	146	37	ints	int	NOUN
fnp-5842	146	38	intermediate	intermediate	ADJ
fnp-5842	146	39	/	/	SYM
fnp-5842	146	40	high	high	ADJ
fnp-5842	146	41	 	 	SPACE
fnp-5842	146	42	=	=	NOUN
fnp-5842	146	43	 	 	SPACE
fnp-5842	146	44	6.5	6.5	NUM
fnp-5842	146	45	 	 	SPACE
fnp-5842	146	46	%	%	NOUN
fnp-5842	146	47	;	;	PUNCT
fnp-5842	146	48	p	p	X
fnp-5842	146	49	 	 	SPACE
fnp-5842	146	50	<	<	X
fnp-5842	146	51	 	 	SPACE
fnp-5842	146	52	0.0001	0.0001	NUM
fnp-5842	146	53	;	;	PUNCT
fnp-5842	146	54	mann	mann	PROPN
fnp-5842	146	55	-	-	PUNCT
fnp-5842	146	56	whitney	whitney	PROPN
fnp-5842	146	57	u	u	PROPN
fnp-5842	146	58	test	test	NOUN
fnp-5842	146	59	;	;	PUNCT
fnp-5842	146	60	n	n	CCONJ
fnp-5842	146	61	 	 	SPACE
fnp-5842	146	62	=	=	NOUN
fnp-5842	146	63	 	 	SPACE
fnp-5842	146	64	118	118	NUM
fnp-5842	146	65	)	)	PUNCT
fnp-5842	146	66	.	.	PUNCT
fnp-5842	147	1	based	base	VERB
fnp-5842	147	2	on	on	ADP
fnp-5842	147	3	methylation	methylation	NOUN
fnp-5842	147	4	-	-	PUNCT
fnp-5842	147	5	based	base	VERB
fnp-5842	147	6	tumor	tumor	NOUN
fnp-5842	147	7	deconvolution	deconvolution	NOUN
fnp-5842	147	8	,	,	PUNCT
fnp-5842	147	9	a	a	DET
fnp-5842	147	10	meningioma	meningioma	NOUN
fnp-5842	147	11	clustering	cluster	VERB
fnp-5842	147	12	according	accord	VERB
fnp-5842	147	13	to	to	ADP
fnp-5842	147	14	histological	histological	ADJ
fnp-5842	147	15	who	who	PRON
fnp-5842	147	16	grades	grade	NOUN
fnp-5842	147	17	is	be	AUX
fnp-5842	147	18	identifiable	identifiable	ADJ
fnp-5842	147	19	(	(	PUNCT
fnp-5842	147	20	n	n	CCONJ
fnp-5842	147	21	 	 	SPACE
fnp-5842	147	22	=	=	NOUN
fnp-5842	147	23	 	 	SPACE
fnp-5842	147	24	107	107	NUM
fnp-5842	147	25	)	)	PUNCT
fnp-5842	147	26	.	.	PUNCT
fnp-5842	148	1	conclusion	conclusion	NOUN
fnp-5842	148	2	:	:	PUNCT
fnp-5842	148	3	ki67	ki67	PROPN
fnp-5842	148	4	-	-	PUNCT
fnp-5842	148	5	focused	focus	VERB
fnp-5842	148	6	wsi	wsi	NOUN
fnp-5842	148	7	and	and	CCONJ
fnp-5842	148	8	tumor	tumor	NOUN
fnp-5842	148	9	deconvolution	deconvolution	NOUN
fnp-5842	148	10	data	datum	NOUN
fnp-5842	148	11	translate	translate	VERB
fnp-5842	148	12	into	into	ADP
fnp-5842	148	13	different	different	ADJ
fnp-5842	148	14	patient	patient	NOUN
fnp-5842	148	15	outcome	outcome	NOUN
fnp-5842	148	16	groups	group	NOUN
fnp-5842	148	17	,	,	PUNCT
fnp-5842	148	18	representing	represent	VERB
fnp-5842	148	19	promising	promise	VERB
fnp-5842	148	20	novel	novel	ADJ
fnp-5842	148	21	biomarkers	biomarker	NOUN
fnp-5842	148	22	for	for	ADP
fnp-5842	148	23	future	future	ADJ
fnp-5842	148	24	integrated	integrate	VERB
fnp-5842	148	25	models	model	NOUN
fnp-5842	148	26	in	in	ADP
fnp-5842	148	27	disease	disease	NOUN
fnp-5842	148	28	course	course	NOUN
fnp-5842	148	29	prognostication	prognostication	NOUN
fnp-5842	148	30	of	of	ADP
fnp-5842	148	31	meningioma	meningioma	NOUN
fnp-5842	148	32	patients	patient	NOUN
fnp-5842	148	33	.	.	PUNCT
fnp-5842	149	1	p11	p11	ADJ
fnp-5842	149	2	free	free	ADJ
fnp-5842	149	3	neuropathol	neuropathol	NOUN
fnp-5842	149	4	5:19:22	5:19:22	NUM
fnp-5842	149	5	cellular	cellular	ADJ
fnp-5842	149	6	senescence	senescence	NOUN
fnp-5842	149	7	as	as	ADP
fnp-5842	149	8	a	a	DET
fnp-5842	149	9	shared	share	VERB
fnp-5842	149	10	contributor	contributor	NOUN
fnp-5842	149	11	to	to	PART
fnp-5842	149	12	disease	disease	NOUN
fnp-5842	149	13	progression	progression	NOUN
fnp-5842	149	14	in	in	ADP
fnp-5842	149	15	glioblastoma	glioblastoma	NOUN
fnp-5842	149	16	and	and	CCONJ
fnp-5842	149	17	alzheimer	alzheimer	PROPN
fnp-5842	149	18	's	's	PART
fnp-5842	149	19	disease	disease	NOUN
fnp-5842	149	20	elena	elena	PROPN
fnp-5842	149	21	krause1,2	krause1,2	PROPN
fnp-5842	149	22	,	,	PUNCT
fnp-5842	149	23	lisa	lisa	PROPN
fnp-5842	149	24	greutter1	greutter1	PROPN
fnp-5842	149	25	,	,	PUNCT
fnp-5842	149	26	daria	daria	PROPN
fnp-5842	149	27	romanovskaia3	romanovskaia3	PROPN
fnp-5842	149	28	,	,	PUNCT
fnp-5842	149	29	peter	peter	PROPN
fnp-5842	149	30	stepper3	stepper3	PROPN
fnp-5842	149	31	,	,	PUNCT
fnp-5842	149	32	felix	felix	PROPN
fnp-5842	149	33	sahm4	sahm4	PROPN
fnp-5842	149	34	,	,	PUNCT
fnp-5842	149	35	adelheid	adelheid	ADJ
fnp-5842	149	36	wöhrer1	wöhrer1	NOUN
fnp-5842	149	37	1	1	NUM
fnp-5842	149	38	medical	medical	ADJ
fnp-5842	149	39	university	university	PROPN
fnp-5842	149	40	of	of	ADP
fnp-5842	149	41	vienna	vienna	PROPN
fnp-5842	149	42	,	,	PUNCT
fnp-5842	149	43	department	department	NOUN
fnp-5842	149	44	of	of	ADP
fnp-5842	149	45	neurology	neurology	NOUN
fnp-5842	149	46	,	,	PUNCT
fnp-5842	149	47	division	division	NOUN
fnp-5842	149	48	of	of	ADP
fnp-5842	149	49	neuropathology	neuropathology	NOUN
fnp-5842	149	50	and	and	CCONJ
fnp-5842	149	51	neurochemistry	neurochemistry	NOUN
fnp-5842	149	52	,	,	PUNCT
fnp-5842	149	53	vienna	vienna	PROPN
fnp-5842	149	54	,	,	PUNCT
fnp-5842	149	55	austria	austria	PROPN
fnp-5842	149	56	2	2	NUM
fnp-5842	149	57	university	university	NOUN
fnp-5842	149	58	of	of	ADP
fnp-5842	149	59	heidelberg	heidelberg	PROPN
fnp-5842	149	60	,	,	PUNCT
fnp-5842	149	61	heidelberg	heidelberg	PROPN
fnp-5842	149	62	,	,	PUNCT
fnp-5842	149	63	germany	germany	PROPN
fnp-5842	149	64	3	3	NUM
fnp-5842	149	65	cemm	cemm	PROPN
fnp-5842	149	66	research	research	NOUN
fnp-5842	149	67	center	center	NOUN
fnp-5842	149	68	for	for	ADP
fnp-5842	149	69	molecular	molecular	ADJ
fnp-5842	149	70	medicine	medicine	NOUN
fnp-5842	149	71	of	of	ADP
fnp-5842	149	72	the	the	DET
fnp-5842	149	73	austrian	austrian	PROPN
fnp-5842	149	74	academy	academy	PROPN
fnp-5842	149	75	of	of	ADP
fnp-5842	149	76	sciences	sciences	PROPN
fnp-5842	149	77	,	,	PUNCT
fnp-5842	149	78	vienna	vienna	PROPN
fnp-5842	149	79	,	,	PUNCT
fnp-5842	149	80	austria	austria	PROPN
fnp-5842	149	81	4	4	NUM
fnp-5842	149	82	department	department	NOUN
fnp-5842	149	83	of	of	ADP
fnp-5842	149	84	neuropathology	neuropathology	NOUN
fnp-5842	149	85	,	,	PUNCT
fnp-5842	149	86	university	university	NOUN
fnp-5842	149	87	hospital	hospital	NOUN
fnp-5842	149	88	heidelberg	heidelberg	PROPN
fnp-5842	149	89	,	,	PUNCT
fnp-5842	149	90	heidelberg	heidelberg	PROPN
fnp-5842	149	91	,	,	PUNCT
fnp-5842	149	92	germany	germany	PROPN
fnp-5842	149	93	introduction	introduction	NOUN
fnp-5842	149	94	:	:	PUNCT
fnp-5842	149	95	neurodegenerative	neurodegenerative	ADJ
fnp-5842	149	96	disorders	disorder	NOUN
fnp-5842	149	97	and	and	CCONJ
fnp-5842	149	98	cancer	cancer	NOUN
fnp-5842	149	99	are	be	AUX
fnp-5842	149	100	increasingly	increasingly	ADV
fnp-5842	149	101	prevalent	prevalent	ADJ
fnp-5842	149	102	in	in	ADP
fnp-5842	149	103	aging	age	VERB
fnp-5842	149	104	populations	population	NOUN
fnp-5842	149	105	.	.	PUNCT
fnp-5842	150	1	over	over	ADP
fnp-5842	150	2	50	50	NUM
fnp-5842	150	3	 	 	SPACE
fnp-5842	150	4	%	%	NOUN
fnp-5842	150	5	of	of	ADP
fnp-5842	150	6	glioblastoma	glioblastoma	NOUN
fnp-5842	150	7	(	(	PUNCT
fnp-5842	150	8	gb	gb	NOUN
fnp-5842	150	9	)	)	PUNCT
fnp-5842	150	10	patients	patient	NOUN
fnp-5842	150	11	show	show	VERB
fnp-5842	150	12	alzheimer	alzheimer	PROPN
fnp-5842	150	13	's	's	PART
fnp-5842	150	14	disease	disease	NOUN
fnp-5842	150	15	neuropathological	neuropathological	ADJ
fnp-5842	150	16	changes	change	NOUN
fnp-5842	150	17	(	(	PUNCT
fnp-5842	150	18	adnc	adnc	ADJ
fnp-5842	150	19	)	)	PUNCT
fnp-5842	150	20	in	in	ADP
fnp-5842	150	21	tumor	tumor	NOUN
fnp-5842	150	22	-	-	PUNCT
fnp-5842	150	23	adjacent	adjacent	ADJ
fnp-5842	150	24	cortex	cortex	NOUN
fnp-5842	150	25	,	,	PUNCT
fnp-5842	150	26	but	but	CCONJ
fnp-5842	150	27	the	the	DET
fnp-5842	150	28	biological	biological	ADJ
fnp-5842	150	29	link	link	NOUN
fnp-5842	150	30	remains	remain	VERB
fnp-5842	150	31	unclear	unclear	ADJ
fnp-5842	150	32	.	.	PUNCT
fnp-5842	151	1	here	here	ADV
fnp-5842	151	2	,	,	PUNCT
fnp-5842	151	3	we	we	PRON
fnp-5842	151	4	investigate	investigate	VERB
fnp-5842	151	5	cellular	cellular	ADJ
fnp-5842	151	6	senescence	senescence	NOUN
fnp-5842	151	7	,	,	PUNCT
fnp-5842	151	8	one	one	NUM
fnp-5842	151	9	hallmark	hallmark	NOUN
fnp-5842	151	10	of	of	ADP
fnp-5842	151	11	aging	aging	NOUN
fnp-5842	151	12	,	,	PUNCT
fnp-5842	151	13	as	as	ADP
fnp-5842	151	14	a	a	DET
fnp-5842	151	15	shared	share	VERB
fnp-5842	151	16	mechanism	mechanism	NOUN
fnp-5842	151	17	of	of	ADP
fnp-5842	151	18	disease	disease	NOUN
fnp-5842	151	19	progression	progression	NOUN
fnp-5842	151	20	.	.	PUNCT
fnp-5842	152	1	methods	method	NOUN
fnp-5842	152	2	:	:	PUNCT
fnp-5842	152	3	we	we	PRON
fnp-5842	152	4	analyzed	analyze	VERB
fnp-5842	152	5	single	single	ADJ
fnp-5842	152	6	cell	cell	NOUN
fnp-5842	152	7	/	/	SYM
fnp-5842	152	8	nucleus	nucleus	NOUN
fnp-5842	152	9	rna	rna	NOUN
fnp-5842	152	10	sequencing	sequencing	NOUN
fnp-5842	152	11	datasets	dataset	NOUN
fnp-5842	152	12	from	from	ADP
fnp-5842	152	13	110	110	NUM
fnp-5842	152	14	gb	gb	NOUN
fnp-5842	152	15	patients	patient	NOUN
fnp-5842	152	16	(	(	PUNCT
fnp-5842	152	17	gbmap	gbmap	PROPN
fnp-5842	152	18	core	core	PROPN
fnp-5842	152	19	atlas	atlas	PROPN
fnp-5842	152	20	)	)	PUNCT
fnp-5842	152	21	and	and	CCONJ
fnp-5842	152	22	89	89	NUM
fnp-5842	152	23	ad	ad	NOUN
fnp-5842	152	24	individuals	individual	NOUN
fnp-5842	152	25	(	(	PUNCT
fnp-5842	152	26	sea	sea	NOUN
fnp-5842	152	27	-	-	PUNCT
fnp-5842	152	28	ad	ad	NOUN
fnp-5842	152	29	mtg	mtg	NOUN
fnp-5842	152	30	atlas	atlas	PROPN
fnp-5842	152	31	)	)	PUNCT
fnp-5842	152	32	.	.	PUNCT
fnp-5842	153	1	using	use	VERB
fnp-5842	153	2	established	establish	VERB
fnp-5842	153	3	senescence	senescence	NOUN
fnp-5842	153	4	gene	gene	NOUN
fnp-5842	153	5	lists	list	NOUN
fnp-5842	153	6	,	,	PUNCT
fnp-5842	153	7	gene	gene	NOUN
fnp-5842	153	8	set	set	VERB
fnp-5842	153	9	enrichment	enrichment	NOUN
fnp-5842	153	10	analysis	analysis	NOUN
fnp-5842	153	11	and	and	CCONJ
fnp-5842	153	12	machine	machine	NOUN
fnp-5842	153	13	learning	learn	VERB
fnp-5842	153	14	we	we	PRON
fnp-5842	153	15	identified	identify	VERB
fnp-5842	153	16	senescent	senescent	ADJ
fnp-5842	153	17	cells	cell	NOUN
fnp-5842	153	18	.	.	PUNCT
fnp-5842	154	1	this	this	PRON
fnp-5842	154	2	allowed	allow	VERB
fnp-5842	154	3	us	we	PRON
fnp-5842	154	4	to	to	PART
fnp-5842	154	5	compare	compare	VERB
fnp-5842	154	6	senescence	senescence	NOUN
fnp-5842	154	7	in	in	ADP
fnp-5842	154	8	cell	cell	NOUN
fnp-5842	154	9	types	type	NOUN
fnp-5842	154	10	,	,	PUNCT
fnp-5842	154	11	subclusters	subcluster	NOUN
fnp-5842	154	12	,	,	PUNCT
fnp-5842	154	13	and	and	CCONJ
fnp-5842	154	14	disease	disease	NOUN
fnp-5842	154	15	stages	stage	NOUN
fnp-5842	154	16	.	.	PUNCT
fnp-5842	155	1	weighted	weight	VERB
fnp-5842	155	2	gene	gene	NOUN
fnp-5842	155	3	co	co	NOUN
fnp-5842	155	4	-	-	NOUN
fnp-5842	155	5	expression	expression	ADJ
fnp-5842	155	6	network	network	NOUN
fnp-5842	155	7	analysis	analysis	NOUN
fnp-5842	155	8	(	(	PUNCT
fnp-5842	155	9	wgcna	wgcna	X
fnp-5842	155	10	)	)	PUNCT
fnp-5842	155	11	identified	identify	VERB
fnp-5842	155	12	senescence	senescence	NOUN
fnp-5842	155	13	-	-	PUNCT
fnp-5842	155	14	associated	associate	VERB
fnp-5842	155	15	co	co	NOUN
fnp-5842	155	16	-	-	NOUN
fnp-5842	155	17	expression	expression	ADJ
fnp-5842	155	18	modules	module	NOUN
fnp-5842	155	19	.	.	PUNCT
fnp-5842	156	1	quantitative	quantitative	ADJ
fnp-5842	156	2	neuropathological	neuropathological	ADJ
fnp-5842	156	3	analysis	analysis	NOUN
fnp-5842	156	4	of	of	ADP
fnp-5842	156	5	published	publish	VERB
fnp-5842	156	6	measurements	measurement	NOUN
fnp-5842	156	7	supported	support	VERB
fnp-5842	156	8	the	the	DET
fnp-5842	156	9	findings	finding	NOUN
fnp-5842	156	10	.	.	PUNCT
fnp-5842	157	1	results	result	NOUN
fnp-5842	157	2	:	:	PUNCT
fnp-5842	157	3	leveraging	leverage	VERB
fnp-5842	157	4	published	publish	VERB
fnp-5842	157	5	datasets	dataset	NOUN
fnp-5842	157	6	,	,	PUNCT
fnp-5842	157	7	we	we	PRON
fnp-5842	157	8	identified	identify	VERB
fnp-5842	157	9	senescent	senescent	ADJ
fnp-5842	157	10	cells	cell	NOUN
fnp-5842	157	11	in	in	ADP
fnp-5842	157	12	gb	gb	NOUN
fnp-5842	157	13	and	and	CCONJ
fnp-5842	157	14	ad	ad	NOUN
fnp-5842	157	15	.	.	PUNCT
fnp-5842	158	1	gb	gb	PRON
fnp-5842	158	2	showed	show	VERB
fnp-5842	158	3	higher	high	ADJ
fnp-5842	158	4	variance	variance	NOUN
fnp-5842	158	5	in	in	ADP
fnp-5842	158	6	senescence	senescence	NOUN
fnp-5842	158	7	scores	score	NOUN
fnp-5842	158	8	,	,	PUNCT
fnp-5842	158	9	indicating	indicate	VERB
fnp-5842	158	10	greater	great	ADJ
fnp-5842	158	11	inter	inter	ADJ
fnp-5842	158	12	-	-	ADJ
fnp-5842	158	13	patient	patient	ADJ
fnp-5842	158	14	variability	variability	NOUN
fnp-5842	158	15	.	.	PUNCT
fnp-5842	159	1	among	among	ADP
fnp-5842	159	2	glial	glial	ADJ
fnp-5842	159	3	cells	cell	NOUN
fnp-5842	159	4	,	,	PUNCT
fnp-5842	159	5	microglia	microglia	NOUN
fnp-5842	159	6	were	be	AUX
fnp-5842	159	7	enriched	enrich	VERB
fnp-5842	159	8	for	for	ADP
fnp-5842	159	9	senescence	senescence	NOUN
fnp-5842	159	10	gene	gene	NOUN
fnp-5842	159	11	sets	set	NOUN
fnp-5842	159	12	,	,	PUNCT
fnp-5842	159	13	with	with	ADP
fnp-5842	159	14	the	the	DET
fnp-5842	159	15	highest	high	ADJ
fnp-5842	159	16	scores	score	NOUN
fnp-5842	159	17	in	in	ADP
fnp-5842	159	18	proinflammatory	proinflammatory	ADJ
fnp-5842	159	19	subtypes	subtype	NOUN
fnp-5842	159	20	.	.	PUNCT
fnp-5842	160	1	using	use	VERB
fnp-5842	160	2	wgcna	wgcna	PROPN
fnp-5842	160	3	we	we	PRON
fnp-5842	160	4	found	find	VERB
fnp-5842	160	5	senescence	senescence	NOUN
fnp-5842	160	6	genes	gene	NOUN
fnp-5842	160	7	co	co	VERB
fnp-5842	160	8	-	-	VERB
fnp-5842	160	9	expressed	express	VERB
fnp-5842	160	10	with	with	ADP
fnp-5842	160	11	known	know	VERB
fnp-5842	160	12	disease	disease	NOUN
fnp-5842	160	13	-	-	PUNCT
fnp-5842	160	14	associated	associate	VERB
fnp-5842	160	15	genes	gene	NOUN
fnp-5842	160	16	like	like	VERB
fnp-5842	160	17	pten	pten	ADJ
fnp-5842	160	18	or	or	CCONJ
fnp-5842	160	19	spp1	spp1	NOUN
fnp-5842	160	20	in	in	ADP
fnp-5842	160	21	ad	ad	NOUN
fnp-5842	160	22	or	or	CCONJ
fnp-5842	160	23	gb	gb	NOUN
fnp-5842	160	24	,	,	PUNCT
fnp-5842	160	25	respectively	respectively	ADV
fnp-5842	160	26	.	.	PUNCT
fnp-5842	161	1	in	in	ADP
fnp-5842	161	2	both	both	DET
fnp-5842	161	3	diseases	disease	NOUN
fnp-5842	161	4	,	,	PUNCT
fnp-5842	161	5	microglia	microglia	ADJ
fnp-5842	161	6	senescence	senescence	NOUN
fnp-5842	161	7	correlated	correlate	VERB
fnp-5842	161	8	with	with	ADP
fnp-5842	161	9	disease	disease	NOUN
fnp-5842	161	10	progression	progression	NOUN
fnp-5842	161	11	.	.	PUNCT
fnp-5842	162	1	accordingly	accordingly	ADV
fnp-5842	162	2	,	,	PUNCT
fnp-5842	162	3	we	we	PRON
fnp-5842	162	4	identified	identify	VERB
fnp-5842	162	5	higher	high	ADJ
fnp-5842	162	6	adnc	adnc	ADJ
fnp-5842	162	7	and	and	CCONJ
fnp-5842	162	8	altered	alter	VERB
fnp-5842	162	9	microglia	microglia	ADJ
fnp-5842	162	10	morphology	morphology	NOUN
fnp-5842	162	11	with	with	ADP
fnp-5842	162	12	signs	sign	NOUN
fnp-5842	162	13	of	of	ADP
fnp-5842	162	14	functional	functional	ADJ
fnp-5842	162	15	exhaustion	exhaustion	NOUN
fnp-5842	162	16	in	in	ADP
fnp-5842	162	17	ad	ad	NOUN
fnp-5842	162	18	specimens	specimen	NOUN
fnp-5842	162	19	with	with	ADP
fnp-5842	162	20	high	high	ADJ
fnp-5842	162	21	senescence	senescence	NOUN
fnp-5842	162	22	scores	score	NOUN
fnp-5842	162	23	.	.	PUNCT
fnp-5842	163	1	conclusion	conclusion	NOUN
fnp-5842	163	2	:	:	PUNCT
fnp-5842	163	3	our	our	PRON
fnp-5842	163	4	atlas	atlas	NOUN
fnp-5842	163	5	-	-	PUNCT
fnp-5842	163	6	level	level	NOUN
fnp-5842	163	7	transcriptomic	transcriptomic	ADJ
fnp-5842	163	8	analysis	analysis	NOUN
fnp-5842	163	9	identifies	identify	VERB
fnp-5842	163	10	cellular	cellular	ADJ
fnp-5842	163	11	senescence	senescence	NOUN
fnp-5842	163	12	as	as	ADP
fnp-5842	163	13	a	a	DET
fnp-5842	163	14	shared	share	VERB
fnp-5842	163	15	mechanism	mechanism	NOUN
fnp-5842	163	16	in	in	ADP
fnp-5842	163	17	gb	gb	ADP
fnp-5842	163	18	and	and	CCONJ
fnp-5842	163	19	ad	ad	NOUN
fnp-5842	163	20	pathology	pathology	NOUN
fnp-5842	163	21	and	and	CCONJ
fnp-5842	163	22	disease	disease	NOUN
fnp-5842	163	23	progression	progression	NOUN
fnp-5842	163	24	,	,	PUNCT
fnp-5842	163	25	particularly	particularly	ADV
fnp-5842	163	26	enriched	enrich	VERB
fnp-5842	163	27	in	in	ADP
fnp-5842	163	28	microglia	microglia	NOUN
fnp-5842	163	29	.	.	PUNCT
fnp-5842	164	1	co	co	NOUN
fnp-5842	164	2	-	-	NOUN
fnp-5842	164	3	expression	expression	NOUN
fnp-5842	164	4	of	of	ADP
fnp-5842	164	5	senescence	senescence	NOUN
fnp-5842	164	6	-	-	PUNCT
fnp-5842	164	7	associated	associate	VERB
fnp-5842	164	8	and	and	CCONJ
fnp-5842	164	9	disease	disease	NOUN
fnp-5842	164	10	-	-	PUNCT
fnp-5842	164	11	specific	specific	ADJ
fnp-5842	164	12	genes	gene	NOUN
fnp-5842	164	13	in	in	ADP
fnp-5842	164	14	microglial	microglial	ADJ
fnp-5842	164	15	modules	module	NOUN
fnp-5842	164	16	highlights	highlight	VERB
fnp-5842	164	17	the	the	DET
fnp-5842	164	18	complex	complex	ADJ
fnp-5842	164	19	role	role	NOUN
fnp-5842	164	20	of	of	ADP
fnp-5842	164	21	senescence	senescence	NOUN
fnp-5842	164	22	in	in	ADP
fnp-5842	164	23	these	these	DET
fnp-5842	164	24	diseases	disease	NOUN
fnp-5842	164	25	.	.	PUNCT
fnp-5842	165	1	p12	p12	VERB
fnp-5842	165	2	free	free	ADJ
fnp-5842	165	3	neuropathol	neuropathol	NOUN
fnp-5842	165	4	5:19:23	5:19:23	NUM
fnp-5842	165	5	vopp1::egfr	vopp1::egfr	NUM
fnp-5842	165	6	gene	gene	NOUN
fnp-5842	165	7	fusion	fusion	NOUN
fnp-5842	165	8	as	as	ADP
fnp-5842	165	9	an	an	DET
fnp-5842	165	10	oncogenic	oncogenic	ADJ
fnp-5842	165	11	driver	driver	NOUN
fnp-5842	165	12	via	via	ADP
fnp-5842	165	13	nfκb	nfκb	ADJ
fnp-5842	165	14	pathway	pathway	NOUN
fnp-5842	165	15	activation	activation	NOUN
fnp-5842	165	16	in	in	ADP
fnp-5842	165	17	a	a	DET
fnp-5842	165	18	case	case	NOUN
fnp-5842	165	19	of	of	ADP
fnp-5842	165	20	ganglioglioma	ganglioglioma	ADJ
fnp-5842	165	21	max	max	PROPN
fnp-5842	165	22	braune1	braune1	PROPN
fnp-5842	165	23	,	,	PUNCT
fnp-5842	165	24	mathias	mathias	PROPN
fnp-5842	165	25	stiller2	stiller2	PROPN
fnp-5842	165	26	,	,	PUNCT
fnp-5842	165	27	cordula	cordula	NOUN
fnp-5842	165	28	scherlach3	scherlach3	PROPN
fnp-5842	165	29	,	,	PUNCT
fnp-5842	165	30	katja	katja	PROPN
fnp-5842	165	31	jähne4	jähne4	PROPN
fnp-5842	165	32	,	,	PUNCT
fnp-5842	165	33	alonso	alonso	PROPN
fnp-5842	165	34	barrantes	barrantes	PROPN
fnp-5842	165	35	-	-	PUNCT
fnp-5842	165	36	freer1	freer1	NOUN
fnp-5842	165	37	1	1	NUM
fnp-5842	165	38	paul	paul	PROPN
fnp-5842	165	39	-	-	PUNCT
fnp-5842	165	40	flechsig	flechsig	NOUN
fnp-5842	165	41	-	-	PUNCT
fnp-5842	165	42	institute	institute	NOUN
fnp-5842	165	43	of	of	ADP
fnp-5842	165	44	neuropathology	neuropathology	NOUN
fnp-5842	165	45	,	,	PUNCT
fnp-5842	165	46	university	university	NOUN
fnp-5842	165	47	hospital	hospital	NOUN
fnp-5842	165	48	leipzig	leipzig	PROPN
fnp-5842	165	49	,	,	PUNCT
fnp-5842	165	50	leipzig	leipzig	PROPN
fnp-5842	165	51	,	,	PUNCT
fnp-5842	165	52	germany	germany	PROPN
fnp-5842	165	53	.	.	PROPN
fnp-5842	166	1	2	2	NUM
fnp-5842	166	2	institute	institute	NOUN
fnp-5842	166	3	of	of	ADP
fnp-5842	166	4	pathology	pathology	PROPN
fnp-5842	166	5	,	,	PUNCT
fnp-5842	166	6	university	university	NOUN
fnp-5842	166	7	hospital	hospital	NOUN
fnp-5842	166	8	leipzig	leipzig	PROPN
fnp-5842	166	9	,	,	PUNCT
fnp-5842	166	10	leipzig	leipzig	PROPN
fnp-5842	166	11	,	,	PUNCT
fnp-5842	166	12	germany	germany	PROPN
fnp-5842	166	13	3	3	NUM
fnp-5842	166	14	institute	institute	PROPN
fnp-5842	166	15	of	of	ADP
fnp-5842	166	16	neuroradiology	neuroradiology	NOUN
fnp-5842	166	17	,	,	PUNCT
fnp-5842	166	18	university	university	NOUN
fnp-5842	166	19	hospital	hospital	NOUN
fnp-5842	166	20	leipzig	leipzig	PROPN
fnp-5842	166	21	,	,	PUNCT
fnp-5842	166	22	leipzig	leipzig	PROPN
fnp-5842	166	23	,	,	PUNCT
fnp-5842	166	24	germany	germany	PROPN
fnp-5842	166	25	4	4	NUM
fnp-5842	166	26	department	department	NOUN
fnp-5842	166	27	of	of	ADP
fnp-5842	166	28	neurosurgery	neurosurgery	NOUN
fnp-5842	166	29	,	,	PUNCT
fnp-5842	166	30	university	university	NOUN
fnp-5842	166	31	hospital	hospital	NOUN
fnp-5842	166	32	leipzig	leipzig	PROPN
fnp-5842	166	33	,	,	PUNCT
fnp-5842	166	34	germany	germany	PROPN
fnp-5842	166	35	ganglioglioma	ganglioglioma	PROPN
fnp-5842	166	36	is	be	AUX
fnp-5842	166	37	a	a	DET
fnp-5842	166	38	well	well	ADV
fnp-5842	166	39	-	-	PUNCT
fnp-5842	166	40	differentiated	differentiate	VERB
fnp-5842	166	41	glioneuronal	glioneuronal	ADJ
fnp-5842	166	42	tumor	tumor	NOUN
fnp-5842	166	43	characterized	characterize	VERB
fnp-5842	166	44	by	by	ADP
fnp-5842	166	45	a	a	DET
fnp-5842	166	46	combination	combination	NOUN
fnp-5842	166	47	of	of	ADP
fnp-5842	166	48	neoplastic	neoplastic	ADJ
fnp-5842	166	49	ganglion	ganglion	NOUN
fnp-5842	166	50	and	and	CCONJ
fnp-5842	166	51	glial	glial	ADJ
fnp-5842	166	52	cells	cell	NOUN
fnp-5842	166	53	.	.	PUNCT
fnp-5842	167	1	oncogenic	oncogenic	ADJ
fnp-5842	167	2	driver	driver	NOUN
fnp-5842	167	3	mutations	mutation	NOUN
fnp-5842	167	4	and	and	CCONJ
fnp-5842	167	5	gene	gene	NOUN
fnp-5842	167	6	fusions	fusion	NOUN
fnp-5842	167	7	have	have	AUX
fnp-5842	167	8	been	be	AUX
fnp-5842	167	9	shown	show	VERB
fnp-5842	167	10	to	to	PART
fnp-5842	167	11	be	be	AUX
fnp-5842	167	12	of	of	ADP
fnp-5842	167	13	prognostic	prognostic	ADJ
fnp-5842	167	14	significance	significance	NOUN
fnp-5842	167	15	in	in	ADP
fnp-5842	167	16	gangliogliomas	ganglioglioma	NOUN
fnp-5842	167	17	and	and	CCONJ
fnp-5842	167	18	can	can	AUX
fnp-5842	167	19	offer	offer	VERB
fnp-5842	167	20	potential	potential	ADJ
fnp-5842	167	21	therapeutic	therapeutic	ADJ
fnp-5842	167	22	targets	target	NOUN
fnp-5842	167	23	.	.	PUNCT
fnp-5842	168	1	typical	typical	ADJ
fnp-5842	168	2	molecular	molecular	ADJ
fnp-5842	168	3	alterations	alteration	NOUN
fnp-5842	168	4	are	be	AUX
fnp-5842	168	5	mapk	mapk	NOUN
fnp-5842	168	6	pathway	pathway	NOUN
fnp-5842	168	7	activations	activation	NOUN
fnp-5842	168	8	with	with	ADP
fnp-5842	168	9	braf	braf	NOUN
fnp-5842	168	10	p.v600e	p.v600e	NOUN
fnp-5842	168	11	being	be	AUX
fnp-5842	168	12	the	the	DET
fnp-5842	168	13	most	most	ADV
fnp-5842	168	14	frequent	frequent	ADJ
fnp-5842	168	15	one	one	NUM
fnp-5842	168	16	.	.	PUNCT
fnp-5842	169	1	here	here	ADV
fnp-5842	169	2	,	,	PUNCT
fnp-5842	169	3	we	we	PRON
fnp-5842	169	4	report	report	VERB
fnp-5842	169	5	for	for	ADP
fnp-5842	169	6	the	the	DET
fnp-5842	169	7	first	first	ADJ
fnp-5842	169	8	time	time	NOUN
fnp-5842	169	9	a	a	DET
fnp-5842	169	10	vopp1::egfr	vopp1::egfr	NOUN
fnp-5842	169	11	gene	gene	NOUN
fnp-5842	169	12	fusion	fusion	NOUN
fnp-5842	169	13	as	as	ADP
fnp-5842	169	14	the	the	DET
fnp-5842	169	15	single	single	ADJ
fnp-5842	169	16	oncogenic	oncogenic	ADJ
fnp-5842	169	17	driver	driver	NOUN
fnp-5842	169	18	in	in	ADP
fnp-5842	169	19	a	a	DET
fnp-5842	169	20	case	case	NOUN
fnp-5842	169	21	of	of	ADP
fnp-5842	169	22	ganglioglioma	ganglioglioma	NOUN
fnp-5842	169	23	leading	lead	VERB
fnp-5842	169	24	to	to	ADP
fnp-5842	169	25	activation	activation	NOUN
fnp-5842	169	26	of	of	ADP
fnp-5842	169	27	nfκb	nfκb	NOUN
fnp-5842	169	28	signaling	signal	VERB
fnp-5842	169	29	.	.	PUNCT
fnp-5842	170	1	we	we	PRON
fnp-5842	170	2	show	show	VERB
fnp-5842	170	3	the	the	DET
fnp-5842	170	4	respective	respective	ADJ
fnp-5842	170	5	histological	histological	ADJ
fnp-5842	170	6	and	and	CCONJ
fnp-5842	170	7	molecular	molecular	ADJ
fnp-5842	170	8	evidence	evidence	NOUN
fnp-5842	170	9	including	include	VERB
fnp-5842	170	10	gene	gene	NOUN
fnp-5842	170	11	fusion	fusion	NOUN
fnp-5842	170	12	and	and	CCONJ
fnp-5842	170	13	mutational	mutational	ADJ
fnp-5842	170	14	analysis	analysis	NOUN
fnp-5842	170	15	,	,	PUNCT
fnp-5842	170	16	methylation	methylation	NOUN
fnp-5842	170	17	profiling	profiling	NOUN
fnp-5842	170	18	and	and	CCONJ
fnp-5842	170	19	clinical	clinical	ADJ
fnp-5842	170	20	outcome	outcome	NOUN
fnp-5842	170	21	.	.	PUNCT
fnp-5842	171	1	the	the	DET
fnp-5842	171	2	case	case	NOUN
fnp-5842	171	3	expands	expand	VERB
fnp-5842	171	4	the	the	DET
fnp-5842	171	5	known	know	VERB
fnp-5842	171	6	molecular	molecular	ADJ
fnp-5842	171	7	spectrum	spectrum	NOUN
fnp-5842	171	8	of	of	ADP
fnp-5842	171	9	oncogenic	oncogenic	ADJ
fnp-5842	171	10	drivers	driver	NOUN
fnp-5842	171	11	in	in	ADP
fnp-5842	171	12	ganglioglioma	ganglioglioma	ADJ
fnp-5842	171	13	linking	link	VERB
fnp-5842	171	14	it	it	PRON
fnp-5842	171	15	with	with	ADP
fnp-5842	171	16	prognostic	prognostic	ADJ
fnp-5842	171	17	and	and	CCONJ
fnp-5842	171	18	potentially	potentially	ADV
fnp-5842	171	19	therapeutically	therapeutically	ADV
fnp-5842	171	20	relevant	relevant	ADJ
fnp-5842	171	21	data	datum	NOUN
fnp-5842	171	22	.	.	PUNCT
fnp-5842	172	1	p13	p13	PROPN
fnp-5842	172	2	free	free	ADJ
fnp-5842	172	3	neuropathol	neuropathol	NOUN
fnp-5842	172	4	5:19:24	5:19:24	NUM
fnp-5842	172	5	insights	insight	NOUN
fnp-5842	172	6	from	from	ADP
fnp-5842	172	7	the	the	DET
fnp-5842	172	8	additional	additional	ADJ
fnp-5842	172	9	immunohistochemical	immunohistochemical	ADJ
fnp-5842	172	10	work	work	NOUN
fnp-5842	172	11	-	-	PUNCT
fnp-5842	172	12	up	up	NOUN
fnp-5842	172	13	of	of	ADP
fnp-5842	172	14	molecular	molecular	ADJ
fnp-5842	172	15	tumor	tumor	NOUN
fnp-5842	172	16	board	board	NOUN
fnp-5842	172	17	patients	patient	NOUN
fnp-5842	172	18	from	from	ADP
fnp-5842	172	19	a	a	DET
fnp-5842	172	20	regional	regional	ADJ
fnp-5842	172	21	brain	brain	NOUN
fnp-5842	172	22	tumor	tumor	NOUN
fnp-5842	172	23	center	center	PROPN
fnp-5842	172	24	elena	elena	PROPN
fnp-5842	172	25	geitner1	geitner1	PROPN
fnp-5842	172	26	,	,	PUNCT
fnp-5842	172	27	tanja	tanja	PROPN
fnp-5842	172	28	rothhammer	rothhammer	PROPN
fnp-5842	172	29	-	-	PUNCT
fnp-5842	172	30	hampl1	hampl1	PROPN
fnp-5842	172	31	,	,	PUNCT
fnp-5842	172	32	christina	christina	PROPN
fnp-5842	172	33	mikolajek1	mikolajek1	PROPN
fnp-5842	172	34	,	,	PUNCT
fnp-5842	172	35	atik	atik	PROPN
fnp-5842	172	36	baborie1	baborie1	PROPN
fnp-5842	172	37	,	,	PUNCT
fnp-5842	172	38	martin	martin	PROPN
fnp-5842	172	39	proescholdt3	proescholdt3	PROPN
fnp-5842	172	40	,	,	PUNCT
fnp-5842	172	41	nils	nils	NOUN
fnp-5842	172	42	-	-	PUNCT
fnp-5842	172	43	ole	ole	NOUN
fnp-5842	172	44	schmidt3	schmidt3	NOUN
fnp-5842	172	45	,	,	PUNCT
fnp-5842	172	46	elisabeth	elisabeth	PROPN
fnp-5842	172	47	bumes2	bumes2	PROPN
fnp-5842	172	48	,	,	PUNCT
fnp-5842	172	49	peter	peter	PROPN
fnp-5842	172	50	hau2	hau2	PROPN
fnp-5842	172	51	,	,	PUNCT
fnp-5842	172	52	markus	markus	PROPN
fnp-5842	172	53	j.	j.	PROPN
fnp-5842	172	54	riemenschneider1	riemenschneider1	PROPN
fnp-5842	172	55	1	1	NUM
fnp-5842	172	56	department	department	NOUN
fnp-5842	172	57	of	of	ADP
fnp-5842	172	58	neuropathology	neuropathology	NOUN
fnp-5842	172	59	,	,	PUNCT
fnp-5842	172	60	regensburg	regensburg	PROPN
fnp-5842	172	61	university	university	PROPN
fnp-5842	172	62	hospital	hospital	NOUN
fnp-5842	172	63	,	,	PUNCT
fnp-5842	172	64	regensburg	regensburg	PROPN
fnp-5842	172	65	,	,	PUNCT
fnp-5842	172	66	germany	germany	PROPN
fnp-5842	172	67	2	2	NUM
fnp-5842	172	68	department	department	NOUN
fnp-5842	172	69	of	of	ADP
fnp-5842	172	70	neurology	neurology	NOUN
fnp-5842	172	71	and	and	CCONJ
fnp-5842	172	72	wilhelm	wilhelm	PROPN
fnp-5842	172	73	sander	sander	PROPN
fnp-5842	172	74	-	-	PUNCT
fnp-5842	172	75	neurooncology	neurooncology	NOUN
fnp-5842	172	76	unit	unit	NOUN
fnp-5842	172	77	,	,	PUNCT
fnp-5842	172	78	regensburg	regensburg	PROPN
fnp-5842	172	79	university	university	PROPN
fnp-5842	172	80	hospital	hospital	NOUN
fnp-5842	172	81	,	,	PUNCT
fnp-5842	172	82	regensburg	regensburg	PROPN
fnp-5842	172	83	,	,	PUNCT
fnp-5842	172	84	germany	germany	PROPN
fnp-5842	172	85	3	3	NUM
fnp-5842	172	86	department	department	NOUN
fnp-5842	172	87	of	of	ADP
fnp-5842	172	88	neurosurgery	neurosurgery	NOUN
fnp-5842	172	89	,	,	PUNCT
fnp-5842	172	90	regensburg	regensburg	PROPN
fnp-5842	172	91	university	university	NOUN
fnp-5842	172	92	hospital	hospital	NOUN
fnp-5842	172	93	,	,	PUNCT
fnp-5842	172	94	regensburg	regensburg	PROPN
fnp-5842	172	95	,	,	PUNCT
fnp-5842	172	96	germany	germany	PROPN
fnp-5842	172	97	patients	patient	NOUN
fnp-5842	172	98	with	with	ADP
fnp-5842	172	99	cns	cns	PROPN
fnp-5842	172	100	/	/	SYM
fnp-5842	172	101	pns	pns	PROPN
fnp-5842	172	102	tumors	tumor	NOUN
fnp-5842	172	103	are	be	AUX
fnp-5842	172	104	included	include	VERB
fnp-5842	172	105	into	into	ADP
fnp-5842	172	106	the	the	DET
fnp-5842	172	107	molecular	molecular	ADJ
fnp-5842	172	108	tumor	tumor	NOUN
fnp-5842	172	109	board	board	NOUN
fnp-5842	172	110	of	of	ADP
fnp-5842	172	111	our	our	PRON
fnp-5842	172	112	local	local	ADJ
fnp-5842	172	113	brain	brain	NOUN
fnp-5842	172	114	tumor	tumor	NOUN
fnp-5842	172	115	center	center	NOUN
fnp-5842	172	116	to	to	ADP
fnp-5842	172	117	defined	define	VERB
fnp-5842	172	118	criteria	criterion	NOUN
fnp-5842	172	119	and	and	CCONJ
fnp-5842	172	120	on	on	ADP
fnp-5842	172	121	a	a	DET
fnp-5842	172	122	regular	regular	ADJ
fnp-5842	172	123	basis	basis	NOUN
fnp-5842	172	124	.	.	PUNCT
fnp-5842	173	1	patients	patient	NOUN
fnp-5842	173	2	discussed	discuss	VERB
fnp-5842	173	3	in	in	ADP
fnp-5842	173	4	the	the	DET
fnp-5842	173	5	period	period	NOUN
fnp-5842	173	6	from	from	ADP
fnp-5842	173	7	22.06.2021	22.06.2021	NUM
fnp-5842	173	8	to	to	ADP
fnp-5842	173	9	30.06.2023	30.06.2023	NUM
fnp-5842	173	10	were	be	AUX
fnp-5842	173	11	selected	select	VERB
fnp-5842	173	12	for	for	ADP
fnp-5842	173	13	accompanying	accompany	VERB
fnp-5842	173	14	immunohistochemical	immunohistochemical	ADJ
fnp-5842	173	15	(	(	PUNCT
fnp-5842	173	16	ihc	ihc	PROPN
fnp-5842	173	17	)	)	PUNCT
fnp-5842	173	18	work	work	NOUN
fnp-5842	173	19	-	-	PUNCT
fnp-5842	173	20	up	up	NOUN
fnp-5842	173	21	in	in	ADP
fnp-5842	173	22	addition	addition	NOUN
fnp-5842	173	23	to	to	ADP
fnp-5842	173	24	comprehensive	comprehensive	ADJ
fnp-5842	173	25	molecular	molecular	ADJ
fnp-5842	173	26	analysis	analysis	NOUN
fnp-5842	173	27	.	.	PUNCT
fnp-5842	174	1	main	main	ADJ
fnp-5842	174	2	objectives	objective	NOUN
fnp-5842	174	3	were	be	AUX
fnp-5842	174	4	to	to	PART
fnp-5842	174	5	substantiate	substantiate	VERB
fnp-5842	174	6	signaling	signal	VERB
fnp-5842	174	7	pathway	pathway	NOUN
fnp-5842	174	8	activation	activation	NOUN
fnp-5842	174	9	and	and	CCONJ
fnp-5842	174	10	to	to	PART
fnp-5842	174	11	identify	identify	VERB
fnp-5842	174	12	biomarkers	biomarker	NOUN
fnp-5842	174	13	harboring	harbor	VERB
fnp-5842	174	14	predictive	predictive	ADJ
fnp-5842	174	15	value	value	NOUN
fnp-5842	174	16	.	.	PUNCT
fnp-5842	175	1	the	the	DET
fnp-5842	175	2	project	project	NOUN
fnp-5842	175	3	was	be	AUX
fnp-5842	175	4	approved	approve	VERB
fnp-5842	175	5	by	by	ADP
fnp-5842	175	6	the	the	DET
fnp-5842	175	7	local	local	ADJ
fnp-5842	175	8	ethics	ethic	NOUN
fnp-5842	175	9	committee	committee	NOUN
fnp-5842	175	10	,	,	PUNCT
fnp-5842	175	11	and	and	CCONJ
fnp-5842	175	12	informed	inform	VERB
fnp-5842	175	13	consent	consent	NOUN
fnp-5842	175	14	was	be	AUX
fnp-5842	175	15	obtained	obtain	VERB
fnp-5842	175	16	from	from	ADP
fnp-5842	175	17	all	all	DET
fnp-5842	175	18	patients	patient	NOUN
fnp-5842	175	19	.	.	PUNCT
fnp-5842	176	1	ffpe	ffpe	ADJ
fnp-5842	176	2	tumor	tumor	NOUN
fnp-5842	176	3	tissues	tissue	NOUN
fnp-5842	176	4	(	(	PUNCT
fnp-5842	176	5	same	same	ADJ
fnp-5842	176	6	material	material	NOUN
fnp-5842	176	7	as	as	SCONJ
fnp-5842	176	8	used	use	VERB
fnp-5842	176	9	for	for	ADP
fnp-5842	176	10	molecular	molecular	ADJ
fnp-5842	176	11	analyses	analysis	NOUN
fnp-5842	176	12	)	)	PUNCT
fnp-5842	176	13	from	from	ADP
fnp-5842	176	14	84	84	NUM
fnp-5842	176	15	patients	patient	NOUN
fnp-5842	176	16	were	be	AUX
fnp-5842	176	17	included	include	VERB
fnp-5842	176	18	on	on	ADP
fnp-5842	176	19	tissue	tissue	NOUN
fnp-5842	176	20	-	-	PUNCT
fnp-5842	176	21	microarrays	microarray	NOUN
fnp-5842	176	22	comprising	comprise	VERB
fnp-5842	176	23	the	the	DET
fnp-5842	176	24	following	follow	VERB
fnp-5842	176	25	entities	entity	NOUN
fnp-5842	176	26	:	:	PUNCT
fnp-5842	176	27	adult-/pediatric	adult-/pediatric	NUM
fnp-5842	176	28	-	-	PUNCT
fnp-5842	176	29	type	type	NOUN
fnp-5842	176	30	diffuse	diffuse	NOUN
fnp-5842	176	31	glioma	glioma	NOUN
fnp-5842	176	32	,	,	PUNCT
fnp-5842	176	33	circumscribed	circumscribed	ADJ
fnp-5842	176	34	glioma	glioma	NOUN
fnp-5842	176	35	,	,	PUNCT
fnp-5842	176	36	ependymoma	ependymoma	NOUN
fnp-5842	176	37	,	,	PUNCT
fnp-5842	176	38	meningioma	meningioma	NOUN
fnp-5842	176	39	,	,	PUNCT
fnp-5842	176	40	medulloblastoma	medulloblastoma	ADJ
fnp-5842	176	41	,	,	PUNCT
fnp-5842	176	42	peripheral	peripheral	ADJ
fnp-5842	176	43	nerve	nerve	NOUN
fnp-5842	176	44	sheath	sheath	NOUN
fnp-5842	176	45	and	and	CCONJ
fnp-5842	176	46	pineal	pineal	ADJ
fnp-5842	176	47	tumor	tumor	NOUN
fnp-5842	176	48	.	.	PUNCT
fnp-5842	177	1	tissue	tissue	NOUN
fnp-5842	177	2	-	-	PUNCT
fnp-5842	177	3	microarrays	microarray	NOUN
fnp-5842	177	4	were	be	AUX
fnp-5842	177	5	analyzed	analyze	VERB
fnp-5842	177	6	immunohistochemically	immunohistochemically	ADV
fnp-5842	177	7	using	use	VERB
fnp-5842	177	8	14	14	NUM
fnp-5842	177	9	different	different	ADJ
fnp-5842	177	10	antibodies	antibody	NOUN
fnp-5842	177	11	:	:	PUNCT
fnp-5842	177	12	p	p	X
fnp-5842	177	13	-	-	PUNCT
fnp-5842	177	14	akt	akt	PROPN
fnp-5842	177	15	,	,	PUNCT
fnp-5842	177	16	p	p	NOUN
fnp-5842	177	17	-	-	PUNCT
fnp-5842	177	18	mtor	mtor	NOUN
fnp-5842	177	19	,	,	PUNCT
fnp-5842	177	20	p	p	NOUN
fnp-5842	177	21	-	-	PUNCT
fnp-5842	177	22	tsc1	tsc1	NOUN
fnp-5842	177	23	,	,	PUNCT
fnp-5842	177	24	p	p	PROPN
fnp-5842	177	25	-	-	PUNCT
fnp-5842	177	26	tsc2	tsc2	NOUN
fnp-5842	177	27	,	,	PUNCT
fnp-5842	177	28	p	p	PROPN
fnp-5842	177	29	-	-	PUNCT
fnp-5842	177	30	s6	s6	PROPN
fnp-5842	177	31	-	-	PUNCT
fnp-5842	177	32	rp	rp	NOUN
fnp-5842	177	33	,	,	PUNCT
fnp-5842	177	34	p	p	NOUN
fnp-5842	177	35	-	-	PUNCT
fnp-5842	177	36	stat3	stat3	NOUN
fnp-5842	177	37	(	(	PUNCT
fnp-5842	177	38	ser727	ser727	PROPN
fnp-5842	177	39	and	and	CCONJ
fnp-5842	177	40	tyr705	tyr705	PROPN
fnp-5842	177	41	)	)	PUNCT
fnp-5842	177	42	,	,	PUNCT
fnp-5842	177	43	p	p	X
fnp-5842	177	44	-	-	PUNCT
fnp-5842	177	45	p42/44	p42/44	VERB
fnp-5842	177	46	mapk(erk1/2	mapk(erk1/2	NOUN
fnp-5842	177	47	)	)	PUNCT
fnp-5842	177	48	,	,	PUNCT
fnp-5842	177	49	p	p	PROPN
fnp-5842	177	50	-	-	PUNCT
fnp-5842	177	51	mek	mek	NOUN
fnp-5842	177	52	,	,	PUNCT
fnp-5842	177	53	p	p	NOUN
fnp-5842	177	54	-	-	PUNCT
fnp-5842	177	55	rb	rb	NOUN
fnp-5842	177	56	,	,	PUNCT
fnp-5842	177	57	mlh1	mlh1	PROPN
fnp-5842	177	58	,	,	PUNCT
fnp-5842	177	59	pms2	pms2	NOUN
fnp-5842	177	60	,	,	PUNCT
fnp-5842	177	61	msh2	msh2	NOUN
fnp-5842	177	62	and	and	CCONJ
fnp-5842	177	63	msh6	msh6	NOUN
fnp-5842	177	64	.	.	PUNCT
fnp-5842	178	1	the	the	DET
fnp-5842	178	2	h	h	NOUN
fnp-5842	178	3	-	-	PUNCT
fnp-5842	178	4	score	score	NOUN
fnp-5842	178	5	was	be	AUX
fnp-5842	178	6	used	use	VERB
fnp-5842	178	7	to	to	PART
fnp-5842	178	8	classify	classify	VERB
fnp-5842	178	9	results	result	NOUN
fnp-5842	178	10	semi	semi	ADJ
fnp-5842	178	11	-	-	ADJ
fnp-5842	178	12	quantitatively	quantitatively	ADV
fnp-5842	178	13	.	.	PUNCT
fnp-5842	179	1	immunohistochemical	immunohistochemical	ADJ
fnp-5842	179	2	results	result	NOUN
fnp-5842	179	3	were	be	AUX
fnp-5842	179	4	correlated	correlate	VERB
fnp-5842	179	5	to	to	ADP
fnp-5842	179	6	molecular	molecular	ADJ
fnp-5842	179	7	alterations	alteration	NOUN
fnp-5842	179	8	and	and	CCONJ
fnp-5842	179	9	revealed	reveal	VERB
fnp-5842	179	10	two	two	NUM
fnp-5842	179	11	significant	significant	ADJ
fnp-5842	179	12	associations	association	NOUN
fnp-5842	179	13	:	:	PUNCT
fnp-5842	179	14	(	(	PUNCT
fnp-5842	179	15	1	1	X
fnp-5842	179	16	)	)	PUNCT
fnp-5842	179	17	patients	patient	NOUN
fnp-5842	179	18	with	with	ADP
fnp-5842	179	19	at	at	ADV
fnp-5842	179	20	least	least	ADV
fnp-5842	179	21	one	one	NUM
fnp-5842	179	22	activating	activate	VERB
fnp-5842	179	23	egfr	egfr	ADJ
fnp-5842	179	24	alteration	alteration	NOUN
fnp-5842	179	25	exhibit	exhibit	NOUN
fnp-5842	179	26	significantly	significantly	ADV
fnp-5842	179	27	lower	low	ADJ
fnp-5842	179	28	phosphorylation	phosphorylation	NOUN
fnp-5842	179	29	and	and	CCONJ
fnp-5842	179	30	activation	activation	NOUN
fnp-5842	179	31	of	of	ADP
fnp-5842	179	32	tsc1	tsc1	NOUN
fnp-5842	179	33	than	than	ADP
fnp-5842	179	34	those	those	PRON
fnp-5842	179	35	without	without	ADP
fnp-5842	179	36	egfr	egfr	ADJ
fnp-5842	179	37	alterations	alteration	NOUN
fnp-5842	179	38	.	.	PUNCT
fnp-5842	180	1	(	(	PUNCT
fnp-5842	180	2	2	2	X
fnp-5842	180	3	)	)	PUNCT
fnp-5842	180	4	expression	expression	NOUN
fnp-5842	180	5	of	of	ADP
fnp-5842	180	6	the	the	DET
fnp-5842	180	7	mismatch	mismatch	ADJ
fnp-5842	180	8	-	-	PUNCT
fnp-5842	180	9	repair	repair	NOUN
fnp-5842	180	10	proteins	protein	NOUN
fnp-5842	180	11	msh2	msh2	NOUN
fnp-5842	180	12	,	,	PUNCT
fnp-5842	180	13	msh6	msh6	NOUN
fnp-5842	180	14	,	,	PUNCT
fnp-5842	180	15	mlh1	mlh1	PROPN
fnp-5842	180	16	and	and	CCONJ
fnp-5842	180	17	pms2	pms2	NOUN
fnp-5842	180	18	was	be	AUX
fnp-5842	180	19	reduced	reduce	VERB
fnp-5842	180	20	in	in	ADP
fnp-5842	180	21	patients	patient	NOUN
fnp-5842	180	22	with	with	ADP
fnp-5842	180	23	a	a	DET
fnp-5842	180	24	nf1	nf1	NOUN
fnp-5842	180	25	mutation	mutation	NOUN
fnp-5842	180	26	.	.	PUNCT
fnp-5842	181	1	in	in	ADP
fnp-5842	181	2	summary	summary	NOUN
fnp-5842	181	3	,	,	PUNCT
fnp-5842	181	4	additional	additional	ADJ
fnp-5842	181	5	ihc	ihc	PROPN
fnp-5842	181	6	work	work	NOUN
fnp-5842	181	7	-	-	PUNCT
fnp-5842	181	8	up	up	NOUN
fnp-5842	181	9	of	of	ADP
fnp-5842	181	10	molecular	molecular	ADJ
fnp-5842	181	11	tumor	tumor	NOUN
fnp-5842	181	12	board	board	NOUN
fnp-5842	181	13	patients	patient	NOUN
fnp-5842	181	14	generated	generate	VERB
fnp-5842	181	15	two	two	NUM
fnp-5842	181	16	interesting	interesting	ADJ
fnp-5842	181	17	scientific	scientific	ADJ
fnp-5842	181	18	findings	finding	NOUN
fnp-5842	181	19	:	:	PUNCT
fnp-5842	181	20	(	(	PUNCT
fnp-5842	181	21	1	1	X
fnp-5842	181	22	)	)	PUNCT
fnp-5842	181	23	p	p	NOUN
fnp-5842	181	24	-	-	PUNCT
fnp-5842	181	25	tsc1	tsc1	NOUN
fnp-5842	181	26	might	might	AUX
fnp-5842	181	27	serve	serve	VERB
fnp-5842	181	28	as	as	ADP
fnp-5842	181	29	a	a	DET
fnp-5842	181	30	surrogate	surrogate	ADJ
fnp-5842	181	31	marker	marker	NOUN
fnp-5842	181	32	for	for	ADP
fnp-5842	181	33	egfr	egfr	ADJ
fnp-5842	181	34	alterations	alteration	NOUN
fnp-5842	181	35	and	and	CCONJ
fnp-5842	181	36	(	(	PUNCT
fnp-5842	181	37	2	2	X
fnp-5842	181	38	)	)	PUNCT
fnp-5842	181	39	a	a	DET
fnp-5842	181	40	potential	potential	ADJ
fnp-5842	181	41	interrelation	interrelation	NOUN
fnp-5842	181	42	between	between	ADP
fnp-5842	181	43	mmr	mmr	PROPN
fnp-5842	181	44	-	-	PUNCT
fnp-5842	181	45	deficiency	deficiency	NOUN
fnp-5842	181	46	and	and	CCONJ
fnp-5842	181	47	mutational	mutational	ADJ
fnp-5842	181	48	inactivation	inactivation	NOUN
fnp-5842	181	49	of	of	ADP
fnp-5842	181	50	nf1	nf1	NOUN
fnp-5842	181	51	exists	exist	VERB
fnp-5842	181	52	.	.	PUNCT
fnp-5842	182	1	the	the	DET
fnp-5842	182	2	exact	exact	ADJ
fnp-5842	182	3	mechanisms	mechanism	NOUN
fnp-5842	182	4	of	of	ADP
fnp-5842	182	5	this	this	DET
fnp-5842	182	6	finding	finding	NOUN
fnp-5842	182	7	,	,	PUNCT
fnp-5842	182	8	however	however	ADV
fnp-5842	182	9	,	,	PUNCT
fnp-5842	182	10	need	need	VERB
fnp-5842	182	11	further	further	ADJ
fnp-5842	182	12	investigation	investigation	NOUN
fnp-5842	182	13	.	.	PUNCT
fnp-5842	183	1	p14	p14	PROPN
fnp-5842	183	2	free	free	ADJ
fnp-5842	183	3	neuropathol	neuropathol	NOUN
fnp-5842	183	4	5:19:25	5:19:25	NUM
fnp-5842	183	5	cytokine	cytokine	ADJ
fnp-5842	183	6	response	response	NOUN
fnp-5842	183	7	in	in	ADP
fnp-5842	183	8	the	the	DET
fnp-5842	183	9	cerebrospinal	cerebrospinal	ADJ
fnp-5842	183	10	fluid	fluid	NOUN
fnp-5842	183	11	after	after	ADP
fnp-5842	183	12	intraoperative	intraoperative	ADJ
fnp-5842	183	13	radiation	radiation	NOUN
fnp-5842	183	14	of	of	ADP
fnp-5842	183	15	primary	primary	ADJ
fnp-5842	183	16	and	and	CCONJ
fnp-5842	183	17	metastatic	metastatic	ADJ
fnp-5842	183	18	brain	brain	NOUN
fnp-5842	183	19	tumors	tumor	NOUN
fnp-5842	183	20	zuzanna	zuzanna	PROPN
fnp-5842	183	21	mielewczyk1,2	mielewczyk1,2	PROPN
fnp-5842	183	22	,	,	PUNCT
fnp-5842	183	23	philipp	philipp	PROPN
fnp-5842	183	24	krauss3	krauss3	PROPN
fnp-5842	183	25	,	,	PUNCT
fnp-5842	183	26	björn	björn	PROPN
fnp-5842	183	27	sommer3	sommer3	PROPN
fnp-5842	183	28	,	,	PUNCT
fnp-5842	183	29	klaus	klaus	PROPN
fnp-5842	183	30	-	-	PUNCT
fnp-5842	183	31	henning	henning	PROPN
fnp-5842	183	32	kahl4	kahl4	PROPN
fnp-5842	183	33	,	,	PUNCT
fnp-5842	183	34	tatiana	tatiana	PROPN
fnp-5842	183	35	mögele2	mögele2	PROPN
fnp-5842	183	36	,	,	PUNCT
fnp-5842	183	37	bruno	bruno	PROPN
fnp-5842	183	38	märkl2	märkl2	PROPN
fnp-5842	183	39	,	,	PUNCT
fnp-5842	183	40	ehab	ehab	PROPN
fnp-5842	183	41	shiban3	shiban3	PROPN
fnp-5842	183	42	,	,	PUNCT
fnp-5842	183	43	friederike	friederike	ADP
fnp-5842	183	44	liesche	liesche	NOUN
fnp-5842	183	45	-	-	PUNCT
fnp-5842	183	46	starnecker1,2	starnecker1,2	PROPN
fnp-5842	183	47	1	1	NUM
fnp-5842	183	48	department	department	NOUN
fnp-5842	183	49	of	of	ADP
fnp-5842	183	50	neuropathology	neuropathology	NOUN
fnp-5842	183	51	,	,	PUNCT
fnp-5842	183	52	pathology	pathology	NOUN
fnp-5842	183	53	,	,	PUNCT
fnp-5842	183	54	medical	medical	ADJ
fnp-5842	183	55	faculty	faculty	NOUN
fnp-5842	183	56	,	,	PUNCT
fnp-5842	183	57	university	university	NOUN
fnp-5842	183	58	of	of	ADP
fnp-5842	183	59	augsburg	augsburg	PROPN
fnp-5842	183	60	,	,	PUNCT
fnp-5842	183	61	germany	germany	PROPN
fnp-5842	183	62	2	2	NUM
fnp-5842	183	63	pathology	pathology	NOUN
fnp-5842	183	64	,	,	PUNCT
fnp-5842	183	65	medical	medical	ADJ
fnp-5842	183	66	faculty	faculty	NOUN
fnp-5842	183	67	,	,	PUNCT
fnp-5842	183	68	university	university	NOUN
fnp-5842	183	69	of	of	ADP
fnp-5842	183	70	augsburg	augsburg	PROPN
fnp-5842	183	71	,	,	PUNCT
fnp-5842	183	72	germany	germany	PROPN
fnp-5842	183	73	3	3	NUM
fnp-5842	183	74	department	department	NOUN
fnp-5842	183	75	of	of	ADP
fnp-5842	183	76	neurosurgery	neurosurgery	NOUN
fnp-5842	183	77	,	,	PUNCT
fnp-5842	183	78	medical	medical	ADJ
fnp-5842	183	79	faculty	faculty	NOUN
fnp-5842	183	80	,	,	PUNCT
fnp-5842	183	81	university	university	NOUN
fnp-5842	183	82	of	of	ADP
fnp-5842	183	83	augsburg	augsburg	PROPN
fnp-5842	183	84	,	,	PUNCT
fnp-5842	183	85	germany	germany	PROPN
fnp-5842	183	86	4	4	NUM
fnp-5842	183	87	department	department	NOUN
fnp-5842	183	88	of	of	ADP
fnp-5842	183	89	radiooncology	radiooncology	NOUN
fnp-5842	183	90	,	,	PUNCT
fnp-5842	183	91	medical	medical	ADJ
fnp-5842	183	92	faculty	faculty	NOUN
fnp-5842	183	93	,	,	PUNCT
fnp-5842	183	94	university	university	NOUN
fnp-5842	183	95	of	of	ADP
fnp-5842	183	96	augsburg	augsburg	PROPN
fnp-5842	183	97	,	,	PUNCT
fnp-5842	183	98	germany	germany	PROPN
fnp-5842	183	99	aim	aim	NOUN
fnp-5842	183	100	of	of	ADP
fnp-5842	183	101	our	our	PRON
fnp-5842	183	102	study	study	NOUN
fnp-5842	183	103	is	be	AUX
fnp-5842	183	104	to	to	PART
fnp-5842	183	105	characterize	characterize	VERB
fnp-5842	183	106	the	the	DET
fnp-5842	183	107	immunological	immunological	ADJ
fnp-5842	183	108	signature	signature	NOUN
fnp-5842	183	109	represented	represent	VERB
fnp-5842	183	110	by	by	ADP
fnp-5842	183	111	the	the	DET
fnp-5842	183	112	cytokine	cytokine	NOUN
fnp-5842	183	113	profile	profile	NOUN
fnp-5842	183	114	in	in	ADP
fnp-5842	183	115	the	the	DET
fnp-5842	183	116	cerebrospinal	cerebrospinal	ADJ
fnp-5842	183	117	fluid	fluid	NOUN
fnp-5842	183	118	(	(	PUNCT
fnp-5842	183	119	csf	csf	NOUN
fnp-5842	183	120	)	)	PUNCT
fnp-5842	183	121	after	after	ADP
fnp-5842	183	122	iort	iort	NOUN
fnp-5842	183	123	of	of	ADP
fnp-5842	183	124	primary	primary	ADJ
fnp-5842	183	125	and	and	CCONJ
fnp-5842	183	126	secondary	secondary	ADJ
fnp-5842	183	127	brain	brain	NOUN
fnp-5842	183	128	tumors	tumor	NOUN
fnp-5842	183	129	.	.	PUNCT
fnp-5842	184	1	for	for	ADP
fnp-5842	184	2	this	this	PRON
fnp-5842	184	3	,	,	PUNCT
fnp-5842	184	4	the	the	DET
fnp-5842	184	5	cytokine	cytokine	NOUN
fnp-5842	184	6	patterns	pattern	NOUN
fnp-5842	184	7	in	in	ADP
fnp-5842	184	8	67	67	NUM
fnp-5842	184	9	csf	csf	ADJ
fnp-5842	184	10	samples	sample	NOUN
fnp-5842	184	11	obtained	obtain	VERB
fnp-5842	184	12	from	from	ADP
fnp-5842	184	13	19	19	NUM
fnp-5842	184	14	patients	patient	NOUN
fnp-5842	184	15	with	with	ADP
fnp-5842	184	16	brain	brain	NOUN
fnp-5842	184	17	tumor	tumor	NOUN
fnp-5842	184	18	resection	resection	NOUN
fnp-5842	184	19	were	be	AUX
fnp-5842	184	20	analyzed	analyze	VERB
fnp-5842	184	21	.	.	PUNCT
fnp-5842	185	1	samples	sample	NOUN
fnp-5842	185	2	were	be	AUX
fnp-5842	185	3	collected	collect	VERB
fnp-5842	185	4	at	at	ADP
fnp-5842	185	5	four	four	NUM
fnp-5842	185	6	time	time	NOUN
fnp-5842	185	7	points	point	NOUN
fnp-5842	185	8	:	:	PUNCT
fnp-5842	186	1	1	1	X
fnp-5842	186	2	.	.	X
fnp-5842	186	3	intraoperatively	intraoperatively	ADV
fnp-5842	186	4	,	,	PUNCT
fnp-5842	186	5	before	before	ADP
fnp-5842	186	6	tumor	tumor	NOUN
fnp-5842	186	7	resection	resection	NOUN
fnp-5842	186	8	and	and	CCONJ
fnp-5842	186	9	iort	iort	NOUN
fnp-5842	186	10	,	,	PUNCT
fnp-5842	186	11	2	2	NUM
fnp-5842	186	12	.	.	PUNCT
fnp-5842	186	13	intraoperatively	intraoperatively	ADV
fnp-5842	186	14	,	,	PUNCT
fnp-5842	186	15	after	after	ADP
fnp-5842	186	16	tumor	tumor	NOUN
fnp-5842	186	17	resection	resection	NOUN
fnp-5842	186	18	,	,	PUNCT
fnp-5842	186	19	before	before	ADP
fnp-5842	186	20	iort	iort	NOUN
fnp-5842	186	21	,	,	PUNCT
fnp-5842	186	22	3	3	X
fnp-5842	186	23	.	.	PUNCT
fnp-5842	186	24	intraoperatively	intraoperatively	ADV
fnp-5842	186	25	,	,	PUNCT
fnp-5842	186	26	after	after	ADP
fnp-5842	186	27	tumor	tumor	NOUN
fnp-5842	186	28	resection	resection	NOUN
fnp-5842	186	29	,	,	PUNCT
fnp-5842	186	30	after	after	ADP
fnp-5842	186	31	iort	iort	NOUN
fnp-5842	186	32	and	and	CCONJ
fnp-5842	186	33	4	4	NUM
fnp-5842	186	34	.	.	X
fnp-5842	186	35	approx	approx	PROPN
fnp-5842	186	36	.	.	PUNCT
fnp-5842	187	1	24	24	NUM
fnp-5842	187	2	hours	hour	NOUN
fnp-5842	187	3	postoperatively	postoperatively	ADV
fnp-5842	187	4	from	from	ADP
fnp-5842	187	5	drainage	drainage	NOUN
fnp-5842	187	6	.	.	PUNCT
fnp-5842	188	1	multiplex	multiplex	PROPN
fnp-5842	188	2	immunoassay	immunoassay	PROPN
fnp-5842	188	3	codeplex	codeplex	PROPN
fnp-5842	188	4	secretome	secretome	NOUN
fnp-5842	188	5	for	for	ADP
fnp-5842	188	6	the	the	DET
fnp-5842	188	7	isospark	isospark	ADJ
fnp-5842	188	8	technology	technology	NOUN
fnp-5842	188	9	was	be	AUX
fnp-5842	188	10	used	use	VERB
fnp-5842	188	11	for	for	ADP
fnp-5842	188	12	level	level	NOUN
fnp-5842	188	13	determination	determination	NOUN
fnp-5842	188	14	of	of	ADP
fnp-5842	188	15	19	19	NUM
fnp-5842	188	16	cytokines	cytokine	NOUN
fnp-5842	188	17	involved	involve	VERB
fnp-5842	188	18	in	in	ADP
fnp-5842	188	19	the	the	DET
fnp-5842	188	20	innate	innate	ADJ
fnp-5842	188	21	immunoresponse	immunoresponse	NOUN
fnp-5842	188	22	.	.	PUNCT
fnp-5842	189	1	an	an	DET
fnp-5842	189	2	increase	increase	NOUN
fnp-5842	189	3	of	of	ADP
fnp-5842	189	4	signal	signal	ADJ
fnp-5842	189	5	intensity	intensity	NOUN
fnp-5842	189	6	was	be	AUX
fnp-5842	189	7	observed	observe	VERB
fnp-5842	189	8	for	for	ADP
fnp-5842	189	9	14	14	NUM
fnp-5842	189	10	of	of	ADP
fnp-5842	189	11	the	the	DET
fnp-5842	189	12	19	19	NUM
fnp-5842	189	13	analyzed	analyze	VERB
fnp-5842	189	14	cytokines	cytokine	NOUN
fnp-5842	189	15	(	(	PUNCT
fnp-5842	189	16	73	73	NUM
fnp-5842	189	17	 	 	SPACE
fnp-5842	189	18	%	%	NOUN
fnp-5842	189	19	)	)	PUNCT
fnp-5842	189	20	in	in	ADP
fnp-5842	189	21	the	the	DET
fnp-5842	189	22	iort	iort	NOUN
fnp-5842	189	23	group	group	NOUN
fnp-5842	189	24	,	,	PUNCT
fnp-5842	189	25	including	include	VERB
fnp-5842	189	26	egf	egf	PROPN
fnp-5842	189	27	,	,	PUNCT
fnp-5842	189	28	granzyme	granzyme	NOUN
fnp-5842	189	29	b	b	NUM
fnp-5842	189	30	,	,	PUNCT
fnp-5842	189	31	il-10	il-10	PRON
fnp-5842	189	32	,	,	PUNCT
fnp-5842	189	33	il-1β	il-1β	PROPN
fnp-5842	189	34	,	,	PUNCT
fnp-5842	189	35	il-6	il-6	PRON
fnp-5842	189	36	,	,	PUNCT
fnp-5842	189	37	il-7	il-7	X
fnp-5842	189	38	,	,	PUNCT
fnp-5842	189	39	il-8	il-8	NOUN
fnp-5842	189	40	,	,	PUNCT
fnp-5842	189	41	ip-10	ip-10	PRON
fnp-5842	189	42	,	,	PUNCT
fnp-5842	189	43	mcp-1	mcp-1	NOUN
fnp-5842	189	44	,	,	PUNCT
fnp-5842	189	45	mip-1α	mip-1α	PROPN
fnp-5842	189	46	,	,	PUNCT
fnp-5842	189	47	mip-1β	mip-1β	PROPN
fnp-5842	189	48	,	,	PUNCT
fnp-5842	189	49	pdgf	pdgf	NOUN
fnp-5842	189	50	-	-	PUNCT
fnp-5842	189	51	bb	bb	NOUN
fnp-5842	189	52	,	,	PUNCT
fnp-5842	189	53	scd137	scd137	NOUN
fnp-5842	189	54	and	and	CCONJ
fnp-5842	189	55	vegf	vegf	PROPN
fnp-5842	189	56	.	.	PUNCT
fnp-5842	190	1	seven	seven	NUM
fnp-5842	190	2	of	of	ADP
fnp-5842	190	3	those	those	DET
fnp-5842	190	4	cytokines	cytokine	NOUN
fnp-5842	190	5	(	(	PUNCT
fnp-5842	190	6	37	37	NUM
fnp-5842	190	7	 	 	SPACE
fnp-5842	190	8	%	%	NOUN
fnp-5842	190	9	)	)	PUNCT
fnp-5842	190	10	displayed	display	VERB
fnp-5842	190	11	a	a	DET
fnp-5842	190	12	significant	significant	ADJ
fnp-5842	190	13	increase	increase	NOUN
fnp-5842	190	14	.	.	PUNCT
fnp-5842	191	1	when	when	SCONJ
fnp-5842	191	2	comparing	compare	VERB
fnp-5842	191	3	the	the	DET
fnp-5842	191	4	time	time	NOUN
fnp-5842	191	5	points	point	NOUN
fnp-5842	191	6	1	1	NUM
fnp-5842	191	7	and	and	CCONJ
fnp-5842	191	8	4	4	NUM
fnp-5842	191	9	between	between	ADP
fnp-5842	191	10	iort	iort	NOUN
fnp-5842	191	11	and	and	CCONJ
fnp-5842	191	12	non	non	ADJ
fnp-5842	191	13	-	-	ADJ
fnp-5842	191	14	iort	iort	ADJ
fnp-5842	191	15	group	group	NOUN
fnp-5842	191	16	,	,	PUNCT
fnp-5842	191	17	the	the	DET
fnp-5842	191	18	increase	increase	NOUN
fnp-5842	191	19	in	in	ADP
fnp-5842	191	20	signal	signal	ADJ
fnp-5842	191	21	intensity	intensity	NOUN
fnp-5842	191	22	for	for	ADP
fnp-5842	191	23	il-1β	il-1β	PROPN
fnp-5842	191	24	,	,	PUNCT
fnp-5842	191	25	il-8	il-8	NOUN
fnp-5842	191	26	,	,	PUNCT
fnp-5842	191	27	ip-10	ip-10	PRON
fnp-5842	191	28	,	,	PUNCT
fnp-5842	191	29	mip-1β	mip-1β	PROPN
fnp-5842	191	30	,	,	PUNCT
fnp-5842	191	31	il-10	il-10	PRON
fnp-5842	191	32	,	,	PUNCT
fnp-5842	191	33	and	and	CCONJ
fnp-5842	191	34	tnf	tnf	PROPN
fnp-5842	191	35	-	-	PUNCT
fnp-5842	191	36	α	α	PROPN
fnp-5842	191	37	in	in	ADP
fnp-5842	191	38	the	the	DET
fnp-5842	191	39	iort	iort	NOUN
fnp-5842	191	40	group	group	NOUN
fnp-5842	191	41	is	be	AUX
fnp-5842	191	42	noticeably	noticeably	ADV
fnp-5842	191	43	greater	great	ADJ
fnp-5842	191	44	than	than	ADP
fnp-5842	191	45	in	in	ADP
fnp-5842	191	46	the	the	DET
fnp-5842	191	47	non	non	ADJ
fnp-5842	191	48	-	-	ADJ
fnp-5842	191	49	iort	iort	ADJ
fnp-5842	191	50	group	group	NOUN
fnp-5842	191	51	,	,	PUNCT
fnp-5842	191	52	although	although	SCONJ
fnp-5842	191	53	not	not	PART
fnp-5842	191	54	significantly	significantly	ADV
fnp-5842	191	55	.	.	PUNCT
fnp-5842	192	1	our	our	PRON
fnp-5842	192	2	results	result	NOUN
fnp-5842	192	3	allow	allow	VERB
fnp-5842	192	4	first	first	ADJ
fnp-5842	192	5	conclusions	conclusion	NOUN
fnp-5842	192	6	about	about	ADP
fnp-5842	192	7	changes	change	NOUN
fnp-5842	192	8	in	in	ADP
fnp-5842	192	9	the	the	DET
fnp-5842	192	10	cytokine	cytokine	ADJ
fnp-5842	192	11	profile	profile	NOUN
fnp-5842	192	12	of	of	ADP
fnp-5842	192	13	csf	csf	NOUN
fnp-5842	192	14	after	after	ADP
fnp-5842	192	15	iort	iort	NOUN
fnp-5842	192	16	of	of	ADP
fnp-5842	192	17	primary	primary	ADJ
fnp-5842	192	18	and	and	CCONJ
fnp-5842	192	19	secondary	secondary	ADJ
fnp-5842	192	20	brain	brain	NOUN
fnp-5842	192	21	tumors	tumor	NOUN
fnp-5842	192	22	.	.	PUNCT
fnp-5842	193	1	the	the	DET
fnp-5842	193	2	results	result	NOUN
fnp-5842	193	3	indicate	indicate	VERB
fnp-5842	193	4	that	that	SCONJ
fnp-5842	193	5	il-1β	il-1β	NOUN
fnp-5842	193	6	,	,	PUNCT
fnp-5842	193	7	il-8	il-8	NOUN
fnp-5842	193	8	,	,	PUNCT
fnp-5842	193	9	ip-10	ip-10	PRON
fnp-5842	193	10	,	,	PUNCT
fnp-5842	193	11	mip-1β	mip-1β	PROPN
fnp-5842	193	12	,	,	PUNCT
fnp-5842	193	13	il-10	il-10	PRON
fnp-5842	193	14	and	and	CCONJ
fnp-5842	193	15	tnf	tnf	PROPN
fnp-5842	193	16	-	-	PUNCT
fnp-5842	193	17	α	α	PROPN
fnp-5842	193	18	are	be	AUX
fnp-5842	193	19	involved	involve	VERB
fnp-5842	193	20	in	in	ADP
fnp-5842	193	21	the	the	DET
fnp-5842	193	22	inflammatory	inflammatory	ADJ
fnp-5842	193	23	response	response	NOUN
fnp-5842	193	24	induced	induce	VERB
fnp-5842	193	25	by	by	ADP
fnp-5842	193	26	exposure	exposure	NOUN
fnp-5842	193	27	to	to	ADP
fnp-5842	193	28	ionizing	ionize	VERB
fnp-5842	193	29	radiation	radiation	NOUN
fnp-5842	193	30	of	of	ADP
fnp-5842	193	31	the	the	DET
fnp-5842	193	32	tumor	tumor	NOUN
fnp-5842	193	33	bed	bed	NOUN
fnp-5842	193	34	during	during	ADP
fnp-5842	193	35	surgery	surgery	NOUN
fnp-5842	193	36	.	.	PUNCT
fnp-5842	194	1	ii	ii	PROPN
fnp-5842	194	2	.	.	PUNCT
fnp-5842	195	1	neuroimmunology	neuroimmunology	PROPN
fnp-5842	195	2	p15	p15	ADJ
fnp-5842	195	3	free	free	ADJ
fnp-5842	195	4	neuropathol	neuropathol	NOUN
fnp-5842	195	5	5:19:26	5:19:26	NUM
fnp-5842	195	6	in	in	ADP
fnp-5842	195	7	-	-	PUNCT
fnp-5842	195	8	depth	depth	NOUN
fnp-5842	195	9	analysis	analysis	NOUN
fnp-5842	195	10	of	of	ADP
fnp-5842	195	11	viral	viral	ADJ
fnp-5842	195	12	distribution	distribution	NOUN
fnp-5842	195	13	and	and	CCONJ
fnp-5842	195	14	immunological	immunological	ADJ
fnp-5842	195	15	profiling	profiling	NOUN
fnp-5842	195	16	in	in	ADP
fnp-5842	195	17	human	human	ADJ
fnp-5842	195	18	bornavirus	bornavirus	NOUN
fnp-5842	195	19	encephalitis	encephalitis	PROPN
fnp-5842	195	20	nicola	nicola	PROPN
fnp-5842	195	21	jungbäck1,2	jungbäck1,2	PROPN
fnp-5842	195	22	,	,	PUNCT
fnp-5842	195	23	tatiana	tatiana	PROPN
fnp-5842	195	24	mögele2	mögele2	PROPN
fnp-5842	195	25	,	,	PUNCT
fnp-5842	195	26	przemyslaw	przemyslaw	NOUN
fnp-5842	195	27	grochowski2	grochowski2	PROPN
fnp-5842	195	28	,	,	PUNCT
fnp-5842	195	29	patrick	patrick	PROPN
fnp-5842	195	30	adam3,4	adam3,4	PROPN
fnp-5842	195	31	,	,	PUNCT
fnp-5842	195	32	thomas	thomas	PROPN
fnp-5842	195	33	pfefferkorn5	pfefferkorn5	PROPN
fnp-5842	195	34	,	,	PUNCT
fnp-5842	195	35	frank	frank	ADJ
fnp-5842	195	36	lippek6	lippek6	PROPN
fnp-5842	195	37	,	,	PUNCT
fnp-5842	195	38	antonios	antonios	PROPN
fnp-5842	195	39	bayas7	bayas7	PROPN
fnp-5842	195	40	,	,	PUNCT
fnp-5842	195	41	thomas	thomas	PROPN
fnp-5842	195	42	richter8	richter8	PROPN
fnp-5842	195	43	,	,	PUNCT
fnp-5842	195	44	georg	georg	NOUN
fnp-5842	195	45	rieder9	rieder9	PROPN
fnp-5842	195	46	,	,	PUNCT
fnp-5842	195	47	bruno	bruno	PROPN
fnp-5842	195	48	märkl2	märkl2	PROPN
fnp-5842	195	49	,	,	PUNCT
fnp-5842	195	50	jürgen	jürgen	PROPN
fnp-5842	195	51	schlegel1,2,4	schlegel1,2,4	PROPN
fnp-5842	195	52	,	,	PUNCT
fnp-5842	195	53	dennis	dennis	PROPN
fnp-5842	195	54	tappe10	tappe10	PROPN
fnp-5842	195	55	,	,	PUNCT
fnp-5842	195	56	friederike	friederike	ADP
fnp-5842	195	57	liesche	liesche	NOUN
fnp-5842	195	58	-	-	PUNCT
fnp-5842	195	59	starnecker1,2	starnecker1,2	PROPN
fnp-5842	195	60	1	1	NUM
fnp-5842	195	61	department	department	NOUN
fnp-5842	195	62	of	of	ADP
fnp-5842	195	63	neuropathology	neuropathology	NOUN
fnp-5842	195	64	,	,	PUNCT
fnp-5842	195	65	pathology	pathology	NOUN
fnp-5842	195	66	,	,	PUNCT
fnp-5842	195	67	medical	medical	ADJ
fnp-5842	195	68	faculty	faculty	NOUN
fnp-5842	195	69	,	,	PUNCT
fnp-5842	195	70	university	university	NOUN
fnp-5842	195	71	of	of	ADP
fnp-5842	195	72	augsburg	augsburg	PROPN
fnp-5842	195	73	,	,	PUNCT
fnp-5842	195	74	augsburg	augsburg	PROPN
fnp-5842	195	75	,	,	PUNCT
fnp-5842	195	76	germany	germany	PROPN
fnp-5842	195	77	2	2	NUM
fnp-5842	195	78	pathology	pathology	NOUN
fnp-5842	195	79	,	,	PUNCT
fnp-5842	195	80	medical	medical	ADJ
fnp-5842	195	81	faculty	faculty	NOUN
fnp-5842	195	82	,	,	PUNCT
fnp-5842	195	83	university	university	NOUN
fnp-5842	195	84	of	of	ADP
fnp-5842	195	85	augsburg	augsburg	PROPN
fnp-5842	195	86	,	,	PUNCT
fnp-5842	195	87	augsburg	augsburg	PROPN
fnp-5842	195	88	,	,	PUNCT
fnp-5842	195	89	germany	germany	PROPN
fnp-5842	195	90	3	3	NUM
fnp-5842	195	91	pathology	pathology	PROPN
fnp-5842	195	92	,	,	PUNCT
fnp-5842	195	93	ingolstadt	ingolstadt	PROPN
fnp-5842	195	94	,	,	PUNCT
fnp-5842	195	95	germany	germany	PROPN
fnp-5842	195	96	4	4	NUM
fnp-5842	195	97	institute	institute	PROPN
fnp-5842	195	98	of	of	ADP
fnp-5842	195	99	pathology	pathology	PROPN
fnp-5842	195	100	,	,	PUNCT
fnp-5842	195	101	school	school	NOUN
fnp-5842	195	102	of	of	ADP
fnp-5842	195	103	medicine	medicine	NOUN
fnp-5842	195	104	and	and	CCONJ
fnp-5842	195	105	health	health	NOUN
fnp-5842	195	106	,	,	PUNCT
fnp-5842	195	107	technical	technical	ADJ
fnp-5842	195	108	university	university	PROPN
fnp-5842	195	109	of	of	ADP
fnp-5842	195	110	munich	munich	PROPN
fnp-5842	195	111	,	,	PUNCT
fnp-5842	195	112	munich	munich	PROPN
fnp-5842	195	113	,	,	PUNCT
fnp-5842	195	114	germany	germany	PROPN
fnp-5842	195	115	5	5	NUM
fnp-5842	195	116	department	department	PROPN
fnp-5842	195	117	of	of	ADP
fnp-5842	195	118	neurology	neurology	NOUN
fnp-5842	195	119	,	,	PUNCT
fnp-5842	195	120	ingolstadt	ingolstadt	NOUN
fnp-5842	195	121	hospital	hospital	NOUN
fnp-5842	195	122	,	,	PUNCT
fnp-5842	195	123	ingolstadt	ingolstadt	NOUN
fnp-5842	195	124	,	,	PUNCT
fnp-5842	195	125	germany	germany	PROPN
fnp-5842	195	126	6	6	NUM
fnp-5842	195	127	institute	institute	PROPN
fnp-5842	195	128	of	of	ADP
fnp-5842	195	129	pathology	pathology	PROPN
fnp-5842	195	130	and	and	CCONJ
fnp-5842	195	131	cytology	cytology	NOUN
fnp-5842	195	132	,	,	PUNCT
fnp-5842	195	133	university	university	NOUN
fnp-5842	195	134	hospital	hospital	NOUN
fnp-5842	195	135	ruppin	ruppin	NOUN
fnp-5842	195	136	-	-	PUNCT
fnp-5842	195	137	brandenburg	brandenburg	PROPN
fnp-5842	195	138	,	,	PUNCT
fnp-5842	195	139	neuruppin	neuruppin	NOUN
fnp-5842	195	140	,	,	PUNCT
fnp-5842	195	141	germany	germany	PROPN
fnp-5842	195	142	7	7	NUM
fnp-5842	195	143	clinic	clinic	NOUN
fnp-5842	195	144	for	for	ADP
fnp-5842	195	145	neurology	neurology	NOUN
fnp-5842	195	146	and	and	CCONJ
fnp-5842	195	147	clinical	clinical	ADJ
fnp-5842	195	148	neurophysiology	neurophysiology	NOUN
fnp-5842	195	149	,	,	PUNCT
fnp-5842	195	150	university	university	NOUN
fnp-5842	195	151	hospital	hospital	NOUN
fnp-5842	195	152	augsburg	augsburg	PROPN
fnp-5842	195	153	,	,	PUNCT
fnp-5842	195	154	augsburg	augsburg	PROPN
fnp-5842	195	155	,	,	PUNCT
fnp-5842	195	156	germany	germany	PROPN
fnp-5842	195	157	8	8	NUM
fnp-5842	195	158	pathology	pathology	NOUN
fnp-5842	195	159	rosenheim	rosenheim	NOUN
fnp-5842	195	160	,	,	PUNCT
fnp-5842	195	161	rosenheim	rosenheim	NOUN
fnp-5842	195	162	,	,	PUNCT
fnp-5842	195	163	germany	germany	PROPN
fnp-5842	195	164	9	9	NUM
fnp-5842	195	165	department	department	PROPN
fnp-5842	195	166	of	of	ADP
fnp-5842	195	167	neurology	neurology	NOUN
fnp-5842	195	168	,	,	PUNCT
fnp-5842	195	169	innklinikum	innklinikum	NOUN
fnp-5842	195	170	,	,	PUNCT
fnp-5842	195	171	altötting	altötting	NOUN
fnp-5842	195	172	,	,	PUNCT
fnp-5842	195	173	germany	germany	PROPN
fnp-5842	195	174	10	10	NUM
fnp-5842	195	175	bernhard	bernhard	PROPN
fnp-5842	195	176	nocht	nocht	PROPN
fnp-5842	195	177	institute	institute	PROPN
fnp-5842	195	178	for	for	ADP
fnp-5842	195	179	tropical	tropical	ADJ
fnp-5842	195	180	medicine	medicine	NOUN
fnp-5842	195	181	,	,	PUNCT
fnp-5842	195	182	national	national	ADJ
fnp-5842	195	183	reference	reference	NOUN
fnp-5842	195	184	centre	centre	NOUN
fnp-5842	195	185	for	for	ADP
fnp-5842	195	186	tropical	tropical	ADJ
fnp-5842	195	187	pathogens	pathogen	NOUN
fnp-5842	195	188	,	,	PUNCT
fnp-5842	195	189	hamburg	hamburg	PROPN
fnp-5842	195	190	,	,	PUNCT
fnp-5842	195	191	germany	germany	PROPN
fnp-5842	195	192	the	the	DET
fnp-5842	195	193	borna	borna	PROPN
fnp-5842	195	194	disease	disease	PROPN
fnp-5842	195	195	virus	virus	NOUN
fnp-5842	195	196	1	1	NUM
fnp-5842	195	197	(	(	PUNCT
fnp-5842	195	198	bodv-1	bodv-1	NOUN
fnp-5842	195	199	)	)	PUNCT
fnp-5842	195	200	has	have	AUX
fnp-5842	195	201	recently	recently	ADV
fnp-5842	195	202	been	be	AUX
fnp-5842	195	203	shown	show	VERB
fnp-5842	195	204	to	to	PART
fnp-5842	195	205	cause	cause	VERB
fnp-5842	195	206	a	a	DET
fnp-5842	195	207	usually	usually	ADV
fnp-5842	195	208	fatal	fatal	ADJ
fnp-5842	195	209	encephalitis	encephalitis	NOUN
fnp-5842	195	210	in	in	ADP
fnp-5842	195	211	humans	human	NOUN
fnp-5842	195	212	.	.	PUNCT
fnp-5842	196	1	to	to	ADP
fnp-5842	196	2	date	date	NOUN
fnp-5842	196	3	,	,	PUNCT
fnp-5842	196	4	little	little	ADJ
fnp-5842	196	5	is	be	AUX
fnp-5842	196	6	known	know	VERB
fnp-5842	196	7	about	about	ADP
fnp-5842	196	8	the	the	DET
fnp-5842	196	9	pathogenesis	pathogenesis	NOUN
fnp-5842	196	10	and	and	CCONJ
fnp-5842	196	11	distribution	distribution	NOUN
fnp-5842	196	12	pattern	pattern	NOUN
fnp-5842	196	13	of	of	ADP
fnp-5842	196	14	the	the	DET
fnp-5842	196	15	virus	virus	NOUN
fnp-5842	196	16	in	in	ADP
fnp-5842	196	17	human	human	ADJ
fnp-5842	196	18	diseases	disease	NOUN
fnp-5842	196	19	.	.	PUNCT
fnp-5842	197	1	aim	aim	NOUN
fnp-5842	197	2	of	of	ADP
fnp-5842	197	3	the	the	DET
fnp-5842	197	4	present	present	ADJ
fnp-5842	197	5	study	study	NOUN
fnp-5842	197	6	is	be	AUX
fnp-5842	197	7	to	to	PART
fnp-5842	197	8	characterize	characterize	VERB
fnp-5842	197	9	the	the	DET
fnp-5842	197	10	virus	virus	NOUN
fnp-5842	197	11	distribution	distribution	NOUN
fnp-5842	197	12	in	in	ADP
fnp-5842	197	13	the	the	DET
fnp-5842	197	14	cns	cns	NOUN
fnp-5842	197	15	and	and	CCONJ
fnp-5842	197	16	profile	profile	VERB
fnp-5842	197	17	the	the	DET
fnp-5842	197	18	immunological	immunological	ADJ
fnp-5842	197	19	processes	process	NOUN
fnp-5842	197	20	in	in	ADP
fnp-5842	197	21	human	human	ADJ
fnp-5842	197	22	bornavirus	bornavirus	NOUN
fnp-5842	197	23	encephalitis	encephalitis	X
fnp-5842	197	24	(	(	PUNCT
fnp-5842	197	25	bve	bve	PROPN
fnp-5842	197	26	)	)	PUNCT
fnp-5842	197	27	.	.	PUNCT
fnp-5842	198	1	complete	complete	ADJ
fnp-5842	198	2	sagittal	sagittal	ADJ
fnp-5842	198	3	and	and	CCONJ
fnp-5842	198	4	coronary	coronary	ADJ
fnp-5842	198	5	sections	section	NOUN
fnp-5842	198	6	of	of	ADP
fnp-5842	198	7	the	the	DET
fnp-5842	198	8	brains	brain	NOUN
fnp-5842	198	9	from	from	ADP
fnp-5842	198	10	four	four	NUM
fnp-5842	198	11	individuals	individual	NOUN
fnp-5842	198	12	who	who	PRON
fnp-5842	198	13	died	die	VERB
fnp-5842	198	14	of	of	ADP
fnp-5842	198	15	bve	bve	PROPN
fnp-5842	198	16	were	be	AUX
fnp-5842	198	17	embedded	embed	VERB
fnp-5842	198	18	and	and	CCONJ
fnp-5842	198	19	stained	stain	VERB
fnp-5842	198	20	immunohistochemically	immunohistochemically	ADV
fnp-5842	198	21	for	for	ADP
fnp-5842	198	22	the	the	DET
fnp-5842	198	23	bodv-1	bodv-1	PROPN
fnp-5842	198	24	nucleoprotein	nucleoprotein	NOUN
fnp-5842	198	25	(	(	PUNCT
fnp-5842	198	26	antibody	antibody	NOUN
fnp-5842	198	27	bo18	bo18	PROPN
fnp-5842	198	28	)	)	PUNCT
fnp-5842	198	29	.	.	PUNCT
fnp-5842	199	1	the	the	DET
fnp-5842	199	2	cross	cros	NOUN
fnp-5842	199	3	-	-	NOUN
fnp-5842	199	4	sections	section	NOUN
fnp-5842	199	5	were	be	AUX
fnp-5842	199	6	then	then	ADV
fnp-5842	199	7	digitally	digitally	ADV
fnp-5842	199	8	reconstructed	reconstruct	VERB
fnp-5842	199	9	,	,	PUNCT
fnp-5842	199	10	and	and	CCONJ
fnp-5842	199	11	the	the	DET
fnp-5842	199	12	amount	amount	NOUN
fnp-5842	199	13	of	of	ADP
fnp-5842	199	14	bodv-1	bodv-1	NOUN
fnp-5842	199	15	-	-	PUNCT
fnp-5842	199	16	positive	positive	ADJ
fnp-5842	199	17	cells	cell	NOUN
fnp-5842	199	18	quantified	quantify	VERB
fnp-5842	199	19	using	use	VERB
fnp-5842	199	20	the	the	DET
fnp-5842	199	21	software	software	NOUN
fnp-5842	199	22	cellquant	cellquant	NOUN
fnp-5842	199	23	.	.	PUNCT
fnp-5842	200	1	furthermore	furthermore	ADV
fnp-5842	200	2	,	,	PUNCT
fnp-5842	200	3	the	the	DET
fnp-5842	200	4	viral	viral	ADJ
fnp-5842	200	5	loads	load	NOUN
fnp-5842	200	6	were	be	AUX
fnp-5842	200	7	estimated	estimate	VERB
fnp-5842	200	8	for	for	ADP
fnp-5842	200	9	each	each	DET
fnp-5842	200	10	block	block	NOUN
fnp-5842	200	11	using	use	VERB
fnp-5842	200	12	qpcr	qpcr	ADV
fnp-5842	200	13	.	.	PUNCT
fnp-5842	201	1	immunological	immunological	ADJ
fnp-5842	201	2	profiling	profiling	NOUN
fnp-5842	201	3	was	be	AUX
fnp-5842	201	4	done	do	VERB
fnp-5842	201	5	using	use	VERB
fnp-5842	201	6	the	the	DET
fnp-5842	201	7	ncounter	ncounter	NOUN
fnp-5842	201	8	technology	technology	NOUN
fnp-5842	201	9	(	(	PUNCT
fnp-5842	201	10	nanostring	nanostre	VERB
fnp-5842	201	11	)	)	PUNCT
fnp-5842	201	12	.	.	PUNCT
fnp-5842	202	1	while	while	SCONJ
fnp-5842	202	2	most	most	ADJ
fnp-5842	202	3	cases	case	NOUN
fnp-5842	202	4	show	show	VERB
fnp-5842	202	5	relatively	relatively	ADV
fnp-5842	202	6	low	low	ADJ
fnp-5842	202	7	virus	virus	NOUN
fnp-5842	202	8	intensities	intensity	NOUN
fnp-5842	202	9	in	in	ADP
fnp-5842	202	10	the	the	DET
fnp-5842	202	11	cerebellum	cerebellum	NOUN
fnp-5842	202	12	,	,	PUNCT
fnp-5842	202	13	the	the	DET
fnp-5842	202	14	basal	basal	ADJ
fnp-5842	202	15	ganglia	ganglia	NOUN
fnp-5842	202	16	,	,	PUNCT
fnp-5842	202	17	brainstem	brainstem	NOUN
fnp-5842	202	18	and	and	CCONJ
fnp-5842	202	19	thalamus	thalamus	NOUN
fnp-5842	202	20	are	be	AUX
fnp-5842	202	21	frequently	frequently	ADV
fnp-5842	202	22	heavily	heavily	ADV
fnp-5842	202	23	affected	affect	VERB
fnp-5842	202	24	as	as	SCONJ
fnp-5842	202	25	estimated	estimate	VERB
fnp-5842	202	26	by	by	ADP
fnp-5842	202	27	both	both	PRON
fnp-5842	202	28	,	,	PUNCT
fnp-5842	202	29	immunohistochemistry	immunohistochemistry	NOUN
fnp-5842	202	30	and	and	CCONJ
fnp-5842	202	31	qpcr	qpcr	ADJ
fnp-5842	202	32	.	.	PUNCT
fnp-5842	203	1	the	the	DET
fnp-5842	203	2	immunological	immunological	ADJ
fnp-5842	203	3	profile	profile	NOUN
fnp-5842	203	4	was	be	AUX
fnp-5842	203	5	examined	examine	VERB
fnp-5842	203	6	for	for	ADP
fnp-5842	203	7	one	one	NUM
fnp-5842	203	8	bodv-1	bodv-1	NOUN
fnp-5842	203	9	case	case	NOUN
fnp-5842	203	10	based	base	VERB
fnp-5842	203	11	on	on	ADP
fnp-5842	203	12	low	low	ADJ
fnp-5842	203	13	,	,	PUNCT
fnp-5842	203	14	medium	medium	ADJ
fnp-5842	203	15	and	and	CCONJ
fnp-5842	203	16	high	high	ADJ
fnp-5842	203	17	viral	viral	ADJ
fnp-5842	203	18	loads	load	NOUN
fnp-5842	203	19	.	.	PUNCT
fnp-5842	204	1	cd56dim	cd56dim	PROPN
fnp-5842	204	2	natural	natural	ADJ
fnp-5842	204	3	killer	killer	NOUN
fnp-5842	204	4	cells	cell	NOUN
fnp-5842	204	5	have	have	VERB
fnp-5842	204	6	the	the	DET
fnp-5842	204	7	highest	high	ADJ
fnp-5842	204	8	scores	score	NOUN
fnp-5842	204	9	in	in	ADP
fnp-5842	204	10	areas	area	NOUN
fnp-5842	204	11	with	with	ADP
fnp-5842	204	12	high	high	ADJ
fnp-5842	204	13	viral	viral	ADJ
fnp-5842	204	14	loads	load	NOUN
fnp-5842	204	15	.	.	PUNCT
fnp-5842	205	1	interestingly	interestingly	ADV
fnp-5842	205	2	,	,	PUNCT
fnp-5842	205	3	regions	region	NOUN
fnp-5842	205	4	with	with	ADP
fnp-5842	205	5	medium	medium	ADJ
fnp-5842	205	6	viral	viral	ADJ
fnp-5842	205	7	loads	load	NOUN
fnp-5842	205	8	show	show	VERB
fnp-5842	205	9	the	the	DET
fnp-5842	205	10	highest	high	ADJ
fnp-5842	205	11	signatures	signature	NOUN
fnp-5842	205	12	for	for	ADP
fnp-5842	205	13	immunological	immunological	ADJ
fnp-5842	205	14	cells	cell	NOUN
fnp-5842	205	15	,	,	PUNCT
fnp-5842	205	16	like	like	ADP
fnp-5842	205	17	cytotoxic	cytotoxic	ADJ
fnp-5842	205	18	cells	cell	NOUN
fnp-5842	205	19	and	and	CCONJ
fnp-5842	205	20	macrophages	macrophage	NOUN
fnp-5842	205	21	.	.	PUNCT
fnp-5842	206	1	bve	bve	PROPN
fnp-5842	206	2	can	can	AUX
fnp-5842	206	3	be	be	AUX
fnp-5842	206	4	considered	consider	VERB
fnp-5842	206	5	a	a	DET
fnp-5842	206	6	model	model	NOUN
fnp-5842	206	7	disease	disease	NOUN
fnp-5842	206	8	for	for	ADP
fnp-5842	206	9	neurotropic	neurotropic	ADJ
fnp-5842	206	10	virus	virus	NOUN
fnp-5842	206	11	infections	infection	NOUN
fnp-5842	206	12	.	.	PUNCT
fnp-5842	207	1	understanding	understand	VERB
fnp-5842	207	2	the	the	DET
fnp-5842	207	3	pathogenesis	pathogenesis	NOUN
fnp-5842	207	4	and	and	CCONJ
fnp-5842	207	5	viral	viral	ADJ
fnp-5842	207	6	spread	spread	NOUN
fnp-5842	207	7	mechanisms	mechanism	NOUN
fnp-5842	207	8	is	be	AUX
fnp-5842	207	9	crucial	crucial	ADJ
fnp-5842	207	10	despite	despite	SCONJ
fnp-5842	207	11	the	the	DET
fnp-5842	207	12	rarity	rarity	NOUN
fnp-5842	207	13	of	of	ADP
fnp-5842	207	14	the	the	DET
fnp-5842	207	15	disease	disease	NOUN
fnp-5842	207	16	.	.	PUNCT
fnp-5842	208	1	a	a	DET
fnp-5842	208	2	standardized	standardized	ADJ
fnp-5842	208	3	,	,	PUNCT
fnp-5842	208	4	comprehensive	comprehensive	ADJ
fnp-5842	208	5	analysis	analysis	NOUN
fnp-5842	208	6	of	of	ADP
fnp-5842	208	7	autopsy	autopsy	ADJ
fnp-5842	208	8	cases	case	NOUN
fnp-5842	208	9	,	,	PUNCT
fnp-5842	208	10	including	include	VERB
fnp-5842	208	11	the	the	DET
fnp-5842	208	12	peripheral	peripheral	ADJ
fnp-5842	208	13	nervous	nervous	ADJ
fnp-5842	208	14	system	system	NOUN
fnp-5842	208	15	,	,	PUNCT
fnp-5842	208	16	is	be	AUX
fnp-5842	208	17	essential	essential	ADJ
fnp-5842	208	18	.	.	PUNCT
fnp-5842	209	1	this	this	PRON
fnp-5842	209	2	will	will	AUX
fnp-5842	209	3	significantly	significantly	ADV
fnp-5842	209	4	enhance	enhance	VERB
fnp-5842	209	5	our	our	PRON
fnp-5842	209	6	understanding	understanding	NOUN
fnp-5842	209	7	and	and	CCONJ
fnp-5842	209	8	management	management	NOUN
fnp-5842	209	9	of	of	ADP
fnp-5842	209	10	such	such	ADJ
fnp-5842	209	11	infections	infection	NOUN
fnp-5842	209	12	.	.	PUNCT
fnp-5842	210	1	p16	p16	PROPN
fnp-5842	210	2	free	free	ADJ
fnp-5842	210	3	neuropathol	neuropathol	NOUN
fnp-5842	210	4	5:19:28	5:19:28	NUM
fnp-5842	210	5	histopathological	histopathological	ADJ
fnp-5842	210	6	analysis	analysis	NOUN
fnp-5842	210	7	of	of	ADP
fnp-5842	210	8	bodv-1	bodv-1	NOUN
fnp-5842	210	9	distribution	distribution	NOUN
fnp-5842	210	10	in	in	ADP
fnp-5842	210	11	a	a	DET
fnp-5842	210	12	non	non	ADJ
fnp-5842	210	13	-	-	ADJ
fnp-5842	210	14	human	human	ADJ
fnp-5842	210	15	primate	primate	NOUN
fnp-5842	210	16	model	model	NOUN
fnp-5842	210	17	:	:	PUNCT
fnp-5842	210	18	comparing	compare	VERB
fnp-5842	210	19	intranasal	intranasal	NOUN
fnp-5842	210	20	and	and	CCONJ
fnp-5842	210	21	subcutaneous	subcutaneous	ADJ
fnp-5842	210	22	inoculation	inoculation	NOUN
fnp-5842	210	23	nicola	nicola	PROPN
fnp-5842	210	24	jungbäck1,2	jungbäck1,2	PROPN
fnp-5842	210	25	,	,	PUNCT
fnp-5842	210	26	przemyslaw	przemyslaw	NOUN
fnp-5842	210	27	grochowski2	grochowski2	PROPN
fnp-5842	210	28	,	,	PUNCT
fnp-5842	210	29	tatiana	tatiana	PROPN
fnp-5842	210	30	mögele2	mögele2	PROPN
fnp-5842	210	31	,	,	PUNCT
fnp-5842	210	32	friederike	friederike	PROPN
fnp-5842	210	33	feldmann3	feldmann3	NOUN
fnp-5842	210	34	,	,	PUNCT
fnp-5842	210	35	heinz	heinz	PROPN
fnp-5842	210	36	feldmann4	feldmann4	PROPN
fnp-5842	210	37	,	,	PUNCT
fnp-5842	210	38	greg	greg	PROPN
fnp-5842	210	39	saturday3	saturday3	PROPN
fnp-5842	210	40	,	,	PUNCT
fnp-5842	210	41	bruno	bruno	PROPN
fnp-5842	210	42	märkl2	märkl2	PROPN
fnp-5842	210	43	,	,	PUNCT
fnp-5842	210	44	martin	martin	PROPN
fnp-5842	210	45	beer5	beer5	PROPN
fnp-5842	210	46	,	,	PUNCT
fnp-5842	210	47	kore	kore	NOUN
fnp-5842	210	48	schlottau5	schlottau5	PROPN
fnp-5842	210	49	,	,	PUNCT
fnp-5842	210	50	friederike	friederike	ADP
fnp-5842	210	51	liesche	liesche	NOUN
fnp-5842	210	52	-	-	PUNCT
fnp-5842	210	53	starnecker1,2	starnecker1,2	PROPN
fnp-5842	210	54	1	1	NUM
fnp-5842	210	55	department	department	NOUN
fnp-5842	210	56	of	of	ADP
fnp-5842	210	57	neuropathology	neuropathology	NOUN
fnp-5842	210	58	,	,	PUNCT
fnp-5842	210	59	pathology	pathology	NOUN
fnp-5842	210	60	,	,	PUNCT
fnp-5842	210	61	medical	medical	ADJ
fnp-5842	210	62	faculty	faculty	NOUN
fnp-5842	210	63	,	,	PUNCT
fnp-5842	210	64	university	university	NOUN
fnp-5842	210	65	of	of	ADP
fnp-5842	210	66	augsburg	augsburg	PROPN
fnp-5842	210	67	,	,	PUNCT
fnp-5842	210	68	augsburg	augsburg	PROPN
fnp-5842	210	69	,	,	PUNCT
fnp-5842	210	70	germany	germany	PROPN
fnp-5842	210	71	2	2	NUM
fnp-5842	210	72	pathology	pathology	NOUN
fnp-5842	210	73	,	,	PUNCT
fnp-5842	210	74	medical	medical	ADJ
fnp-5842	210	75	faculty	faculty	NOUN
fnp-5842	210	76	,	,	PUNCT
fnp-5842	210	77	university	university	NOUN
fnp-5842	210	78	of	of	ADP
fnp-5842	210	79	augsburg	augsburg	PROPN
fnp-5842	210	80	,	,	PUNCT
fnp-5842	210	81	augsburg	augsburg	PROPN
fnp-5842	210	82	,	,	PUNCT
fnp-5842	210	83	germany	germany	PROPN
fnp-5842	210	84	3	3	NUM
fnp-5842	210	85	rocky	rocky	ADJ
fnp-5842	210	86	mountain	mountain	NOUN
fnp-5842	210	87	veterinary	veterinary	ADJ
fnp-5842	210	88	branch	branch	NOUN
fnp-5842	210	89	,	,	PUNCT
fnp-5842	210	90	division	division	NOUN
fnp-5842	210	91	of	of	ADP
fnp-5842	210	92	intramural	intramural	ADJ
fnp-5842	210	93	research	research	NOUN
fnp-5842	210	94	,	,	PUNCT
fnp-5842	210	95	national	national	PROPN
fnp-5842	210	96	institute	institute	PROPN
fnp-5842	210	97	of	of	ADP
fnp-5842	210	98	allergy	allergy	PROPN
fnp-5842	210	99	and	and	CCONJ
fnp-5842	210	100	infectious	infectious	ADJ
fnp-5842	210	101	diseases	disease	NOUN
fnp-5842	210	102	,	,	PUNCT
fnp-5842	210	103	national	national	ADJ
fnp-5842	210	104	institutes	institutes	PROPN
fnp-5842	210	105	of	of	ADP
fnp-5842	210	106	health	health	PROPN
fnp-5842	210	107	,	,	PUNCT
fnp-5842	210	108	hamilton	hamilton	PROPN
fnp-5842	210	109	,	,	PUNCT
fnp-5842	210	110	usa	usa	PROPN
fnp-5842	210	111	4	4	NUM
fnp-5842	210	112	laboratory	laboratory	NOUN
fnp-5842	210	113	of	of	ADP
fnp-5842	210	114	virology	virology	NOUN
fnp-5842	210	115	,	,	PUNCT
fnp-5842	210	116	division	division	NOUN
fnp-5842	210	117	of	of	ADP
fnp-5842	210	118	intramural	intramural	ADJ
fnp-5842	210	119	research	research	NOUN
fnp-5842	210	120	,	,	PUNCT
fnp-5842	210	121	national	national	PROPN
fnp-5842	210	122	institute	institute	PROPN
fnp-5842	210	123	of	of	ADP
fnp-5842	210	124	allergy	allergy	PROPN
fnp-5842	210	125	and	and	CCONJ
fnp-5842	210	126	infectious	infectious	ADJ
fnp-5842	210	127	diseases	disease	NOUN
fnp-5842	210	128	,	,	PUNCT
fnp-5842	210	129	national	national	ADJ
fnp-5842	210	130	institutes	institutes	PROPN
fnp-5842	210	131	of	of	ADP
fnp-5842	210	132	health	health	PROPN
fnp-5842	210	133	,	,	PUNCT
fnp-5842	210	134	hamilton	hamilton	PROPN
fnp-5842	210	135	,	,	PUNCT
fnp-5842	210	136	usa	usa	PROPN
fnp-5842	210	137	5	5	NUM
fnp-5842	210	138	institute	institute	PROPN
fnp-5842	210	139	of	of	ADP
fnp-5842	210	140	diagnostic	diagnostic	ADJ
fnp-5842	210	141	virology	virology	NOUN
fnp-5842	210	142	,	,	PUNCT
fnp-5842	210	143	friedrich	friedrich	NOUN
fnp-5842	210	144	-	-	PUNCT
fnp-5842	210	145	loeffler	loeffler	NOUN
fnp-5842	210	146	-	-	PUNCT
fnp-5842	210	147	institut	institut	PROPN
fnp-5842	210	148	,	,	PUNCT
fnp-5842	210	149	greifswald	greifswald	PROPN
fnp-5842	210	150	-	-	PUNCT
fnp-5842	210	151	insel	insel	PROPN
fnp-5842	210	152	riems	riem	NOUN
fnp-5842	210	153	,	,	PUNCT
fnp-5842	210	154	germany	germany	PROPN
fnp-5842	210	155	borna	borna	PROPN
fnp-5842	210	156	disease	disease	PROPN
fnp-5842	210	157	virus	virus	NOUN
fnp-5842	210	158	1	1	NUM
fnp-5842	210	159	(	(	PUNCT
fnp-5842	210	160	bodv-1	bodv-1	NOUN
fnp-5842	210	161	)	)	PUNCT
fnp-5842	210	162	is	be	AUX
fnp-5842	210	163	known	know	VERB
fnp-5842	210	164	to	to	PART
fnp-5842	210	165	cause	cause	VERB
fnp-5842	210	166	fatal	fatal	ADJ
fnp-5842	210	167	encephalitis	encephalitis	NOUN
fnp-5842	210	168	in	in	ADP
fnp-5842	210	169	humans	human	NOUN
fnp-5842	210	170	,	,	PUNCT
fnp-5842	210	171	yet	yet	CCONJ
fnp-5842	210	172	the	the	DET
fnp-5842	210	173	mechanisms	mechanism	NOUN
fnp-5842	210	174	and	and	CCONJ
fnp-5842	210	175	distribution	distribution	NOUN
fnp-5842	210	176	of	of	ADP
fnp-5842	210	177	the	the	DET
fnp-5842	210	178	virus	virus	NOUN
fnp-5842	210	179	within	within	ADP
fnp-5842	210	180	the	the	DET
fnp-5842	210	181	brain	brain	NOUN
fnp-5842	210	182	remain	remain	AUX
fnp-5842	210	183	poorly	poorly	ADV
fnp-5842	210	184	understood	understand	VERB
fnp-5842	210	185	.	.	PUNCT
fnp-5842	211	1	this	this	DET
fnp-5842	211	2	study	study	NOUN
fnp-5842	211	3	investigates	investigate	VERB
fnp-5842	211	4	the	the	DET
fnp-5842	211	5	histopathological	histopathological	ADJ
fnp-5842	211	6	impact	impact	NOUN
fnp-5842	211	7	of	of	ADP
fnp-5842	211	8	bodv-1	bodv-1	NUM
fnp-5842	211	9	in	in	ADP
fnp-5842	211	10	a	a	DET
fnp-5842	211	11	non	non	ADJ
fnp-5842	211	12	-	-	ADJ
fnp-5842	211	13	human	human	ADJ
fnp-5842	211	14	primate	primate	NOUN
fnp-5842	211	15	model	model	NOUN
fnp-5842	211	16	.	.	PUNCT
fnp-5842	212	1	twelve	twelve	NUM
fnp-5842	212	2	macaques	macaque	NOUN
fnp-5842	212	3	were	be	AUX
fnp-5842	212	4	infected	infect	VERB
fnp-5842	212	5	with	with	ADP
fnp-5842	212	6	bodv-1	bodv-1	PROPN
fnp-5842	212	7	,	,	PUNCT
fnp-5842	212	8	with	with	ADP
fnp-5842	212	9	six	six	NUM
fnp-5842	212	10	receiving	receive	VERB
fnp-5842	212	11	intranasal	intranasal	NOUN
fnp-5842	212	12	inoculation	inoculation	NOUN
fnp-5842	212	13	which	which	PRON
fnp-5842	212	14	reflects	reflect	VERB
fnp-5842	212	15	the	the	DET
fnp-5842	212	16	currently	currently	ADV
fnp-5842	212	17	hypothesized	hypothesize	VERB
fnp-5842	212	18	portal	portal	NOUN
fnp-5842	212	19	of	of	ADP
fnp-5842	212	20	entry	entry	NOUN
fnp-5842	212	21	,	,	PUNCT
fnp-5842	212	22	and	and	CCONJ
fnp-5842	212	23	six	six	NUM
fnp-5842	212	24	receiving	receive	VERB
fnp-5842	212	25	subcutaneous	subcutaneous	ADJ
fnp-5842	212	26	inoculation	inoculation	NOUN
fnp-5842	212	27	as	as	ADP
fnp-5842	212	28	setting	set	VERB
fnp-5842	212	29	for	for	ADP
fnp-5842	212	30	infection	infection	NOUN
fnp-5842	212	31	via	via	ADP
fnp-5842	212	32	the	the	DET
fnp-5842	212	33	peripheral	peripheral	ADJ
fnp-5842	212	34	nervous	nervous	ADJ
fnp-5842	212	35	system	system	NOUN
fnp-5842	212	36	.	.	PUNCT
fnp-5842	213	1	the	the	DET
fnp-5842	213	2	primary	primary	ADJ
fnp-5842	213	3	focus	focus	NOUN
fnp-5842	213	4	of	of	ADP
fnp-5842	213	5	this	this	DET
fnp-5842	213	6	project	project	NOUN
fnp-5842	213	7	is	be	AUX
fnp-5842	213	8	the	the	DET
fnp-5842	213	9	histopathological	histopathological	ADJ
fnp-5842	213	10	examination	examination	NOUN
fnp-5842	213	11	of	of	ADP
fnp-5842	213	12	the	the	DET
fnp-5842	213	13	brains	brain	NOUN
fnp-5842	213	14	to	to	PART
fnp-5842	213	15	determine	determine	VERB
fnp-5842	213	16	the	the	DET
fnp-5842	213	17	differences	difference	NOUN
fnp-5842	213	18	of	of	ADP
fnp-5842	213	19	the	the	DET
fnp-5842	213	20	viral	viral	ADJ
fnp-5842	213	21	distribution	distribution	NOUN
fnp-5842	213	22	in	in	ADP
fnp-5842	213	23	the	the	DET
fnp-5842	213	24	two	two	NUM
fnp-5842	213	25	settings	setting	NOUN
fnp-5842	213	26	of	of	ADP
fnp-5842	213	27	infection	infection	NOUN
fnp-5842	213	28	.	.	PUNCT
fnp-5842	214	1	complete	complete	ADJ
fnp-5842	214	2	sagittal	sagittal	ADJ
fnp-5842	214	3	sections	section	NOUN
fnp-5842	214	4	of	of	ADP
fnp-5842	214	5	the	the	DET
fnp-5842	214	6	brains	brain	NOUN
fnp-5842	214	7	were	be	AUX
fnp-5842	214	8	embedded	embed	VERB
fnp-5842	214	9	and	and	CCONJ
fnp-5842	214	10	immunohistochemically	immunohistochemically	ADV
fnp-5842	214	11	stained	stain	VERB
fnp-5842	214	12	targeting	target	VERB
fnp-5842	214	13	the	the	DET
fnp-5842	214	14	bodv-1	bodv-1	PROPN
fnp-5842	214	15	nucleoprotein	nucleoprotein	NOUN
fnp-5842	214	16	.	.	PUNCT
fnp-5842	215	1	the	the	DET
fnp-5842	215	2	stained	stained	ADJ
fnp-5842	215	3	sections	section	NOUN
fnp-5842	215	4	were	be	AUX
fnp-5842	215	5	digitally	digitally	ADV
fnp-5842	215	6	reconstructed	reconstruct	VERB
fnp-5842	215	7	,	,	PUNCT
fnp-5842	215	8	allowing	allow	VERB
fnp-5842	215	9	for	for	ADP
fnp-5842	215	10	a	a	DET
fnp-5842	215	11	detailed	detailed	ADJ
fnp-5842	215	12	analysis	analysis	NOUN
fnp-5842	215	13	of	of	ADP
fnp-5842	215	14	the	the	DET
fnp-5842	215	15	virus	virus	NOUN
fnp-5842	215	16	'	'	PART
fnp-5842	215	17	distribution	distribution	NOUN
fnp-5842	215	18	.	.	PUNCT
fnp-5842	216	1	quantitative	quantitative	ADJ
fnp-5842	216	2	assessment	assessment	NOUN
fnp-5842	216	3	was	be	AUX
fnp-5842	216	4	performed	perform	VERB
fnp-5842	216	5	using	use	VERB
fnp-5842	216	6	the	the	DET
fnp-5842	216	7	software	software	NOUN
fnp-5842	216	8	cellquant	cellquant	NOUN
fnp-5842	216	9	.	.	PUNCT
fnp-5842	217	1	preliminary	preliminary	ADJ
fnp-5842	217	2	results	result	NOUN
fnp-5842	217	3	indicate	indicate	VERB
fnp-5842	217	4	differential	differential	ADJ
fnp-5842	217	5	patterns	pattern	NOUN
fnp-5842	217	6	of	of	ADP
fnp-5842	217	7	viral	viral	ADJ
fnp-5842	217	8	spread	spread	NOUN
fnp-5842	217	9	and	and	CCONJ
fnp-5842	217	10	intensity	intensity	NOUN
fnp-5842	217	11	between	between	ADP
fnp-5842	217	12	the	the	DET
fnp-5842	217	13	two	two	NUM
fnp-5842	217	14	inoculation	inoculation	ADJ
fnp-5842	217	15	methods	method	NOUN
fnp-5842	217	16	.	.	PUNCT
fnp-5842	218	1	intranasally	intranasally	ADV
fnp-5842	218	2	infected	infect	VERB
fnp-5842	218	3	macaques	macaque	NOUN
fnp-5842	218	4	showed	show	VERB
fnp-5842	218	5	a	a	DET
fnp-5842	218	6	higher	high	ADJ
fnp-5842	218	7	concentration	concentration	NOUN
fnp-5842	218	8	of	of	ADP
fnp-5842	218	9	bodv-1	bodv-1	ADJ
fnp-5842	218	10	-	-	PUNCT
fnp-5842	218	11	positive	positive	ADJ
fnp-5842	218	12	cells	cell	NOUN
fnp-5842	218	13	in	in	ADP
fnp-5842	218	14	the	the	DET
fnp-5842	218	15	olfactory	olfactory	NOUN
fnp-5842	218	16	bulb	bulb	NOUN
fnp-5842	218	17	,	,	PUNCT
fnp-5842	218	18	spreading	spread	VERB
fnp-5842	218	19	to	to	ADP
fnp-5842	218	20	the	the	DET
fnp-5842	218	21	frontal	frontal	ADJ
fnp-5842	218	22	cortex	cortex	NOUN
fnp-5842	218	23	and	and	CCONJ
fnp-5842	218	24	deeper	deep	ADJ
fnp-5842	218	25	brain	brain	NOUN
fnp-5842	218	26	structures	structure	NOUN
fnp-5842	218	27	.	.	PUNCT
fnp-5842	219	1	subcutaneously	subcutaneously	ADV
fnp-5842	219	2	infected	infect	VERB
fnp-5842	219	3	macaques	macaque	NOUN
fnp-5842	219	4	demonstrated	demonstrate	VERB
fnp-5842	219	5	a	a	DET
fnp-5842	219	6	more	more	ADV
fnp-5842	219	7	dispersed	disperse	VERB
fnp-5842	219	8	viral	viral	ADJ
fnp-5842	219	9	distribution	distribution	NOUN
fnp-5842	219	10	with	with	ADP
fnp-5842	219	11	generally	generally	ADV
fnp-5842	219	12	lower	low	ADJ
fnp-5842	219	13	virus	virus	NOUN
fnp-5842	219	14	detection	detection	NOUN
fnp-5842	219	15	.	.	PUNCT
fnp-5842	220	1	this	this	DET
fnp-5842	220	2	study	study	NOUN
fnp-5842	220	3	provides	provide	VERB
fnp-5842	220	4	valuable	valuable	ADJ
fnp-5842	220	5	insights	insight	NOUN
fnp-5842	220	6	into	into	ADP
fnp-5842	220	7	the	the	DET
fnp-5842	220	8	pathogenesis	pathogenesis	NOUN
fnp-5842	220	9	of	of	ADP
fnp-5842	220	10	bodv-1	bodv-1	PROPN
fnp-5842	220	11	,	,	PUNCT
fnp-5842	220	12	highlighting	highlight	VERB
fnp-5842	220	13	the	the	DET
fnp-5842	220	14	importance	importance	NOUN
fnp-5842	220	15	of	of	ADP
fnp-5842	220	16	the	the	DET
fnp-5842	220	17	route	route	NOUN
fnp-5842	220	18	of	of	ADP
fnp-5842	220	19	infection	infection	NOUN
fnp-5842	220	20	in	in	ADP
fnp-5842	220	21	determining	determine	VERB
fnp-5842	220	22	viral	viral	ADJ
fnp-5842	220	23	spread	spread	NOUN
fnp-5842	220	24	within	within	ADP
fnp-5842	220	25	the	the	DET
fnp-5842	220	26	cns	cns	NOUN
fnp-5842	220	27	.	.	PUNCT
fnp-5842	221	1	the	the	DET
fnp-5842	221	2	findings	finding	NOUN
fnp-5842	221	3	emphasize	emphasize	VERB
fnp-5842	221	4	the	the	DET
fnp-5842	221	5	need	need	NOUN
fnp-5842	221	6	for	for	ADP
fnp-5842	221	7	comprehensive	comprehensive	ADJ
fnp-5842	221	8	histopathological	histopathological	ADJ
fnp-5842	221	9	analysis	analysis	NOUN
fnp-5842	221	10	to	to	PART
fnp-5842	221	11	enhance	enhance	VERB
fnp-5842	221	12	our	our	PRON
fnp-5842	221	13	understanding	understanding	NOUN
fnp-5842	221	14	of	of	ADP
fnp-5842	221	15	bodv-1	bodv-1	NUM
fnp-5842	221	16	and	and	CCONJ
fnp-5842	221	17	its	its	PRON
fnp-5842	221	18	implications	implication	NOUN
fnp-5842	221	19	for	for	ADP
fnp-5842	221	20	neurotropic	neurotropic	ADJ
fnp-5842	221	21	virus	virus	NOUN
fnp-5842	221	22	infections	infection	NOUN
fnp-5842	221	23	.	.	PUNCT
fnp-5842	222	1	p17	p17	ADJ
fnp-5842	222	2	free	free	ADJ
fnp-5842	222	3	neuropathol	neuropathol	NOUN
fnp-5842	222	4	5:19:29	5:19:29	NUM
fnp-5842	222	5	systematic	systematic	ADJ
fnp-5842	222	6	analysis	analysis	NOUN
fnp-5842	222	7	of	of	ADP
fnp-5842	222	8	virus	virus	NOUN
fnp-5842	222	9	spread	spread	VERB
fnp-5842	222	10	to	to	ADP
fnp-5842	222	11	the	the	DET
fnp-5842	222	12	peripheral	peripheral	ADJ
fnp-5842	222	13	nervous	nervous	ADJ
fnp-5842	222	14	system	system	NOUN
fnp-5842	222	15	in	in	ADP
fnp-5842	222	16	fatal	fatal	ADJ
fnp-5842	222	17	borna	borna	PROPN
fnp-5842	222	18	virus	virus	NOUN
fnp-5842	222	19	encephalitis	encephalitis	NOUN
fnp-5842	222	20	przemyslaw	przemyslaw	NOUN
fnp-5842	222	21	grochowski1	grochowski1	PROPN
fnp-5842	222	22	,	,	PUNCT
fnp-5842	222	23	nicola	nicola	PROPN
fnp-5842	222	24	jungbäck1,2	jungbäck1,2	PROPN
fnp-5842	222	25	,	,	PUNCT
fnp-5842	222	26	tina	tina	PROPN
fnp-5842	222	27	schaller1	schaller1	PROPN
fnp-5842	222	28	,	,	PUNCT
fnp-5842	222	29	frank	frank	PROPN
fnp-5842	222	30	lippek3	lippek3	PROPN
fnp-5842	222	31	,	,	PUNCT
fnp-5842	222	32	patrick	patrick	PROPN
fnp-5842	222	33	adam4,5	adam4,5	PROPN
fnp-5842	222	34	,	,	PUNCT
fnp-5842	222	35	thomas	thomas	PROPN
fnp-5842	222	36	pfefferkorn6	pfefferkorn6	PROPN
fnp-5842	222	37	,	,	PUNCT
fnp-5842	222	38	jürgen	jürgen	PROPN
fnp-5842	222	39	schlegel1,2,4	schlegel1,2,4	NOUN
fnp-5842	222	40	,	,	PUNCT
fnp-5842	222	41	bruno	bruno	PROPN
fnp-5842	222	42	märkl1	märkl1	PROPN
fnp-5842	222	43	,	,	PUNCT
fnp-5842	222	44	friederike	friederike	ADP
fnp-5842	222	45	liesche	liesche	NOUN
fnp-5842	222	46	-	-	PUNCT
fnp-5842	222	47	starnecker1,2	starnecker1,2	PROPN
fnp-5842	222	48	1	1	NUM
fnp-5842	222	49	pathology	pathology	NOUN
fnp-5842	222	50	,	,	PUNCT
fnp-5842	222	51	medical	medical	ADJ
fnp-5842	222	52	faculty	faculty	NOUN
fnp-5842	222	53	,	,	PUNCT
fnp-5842	222	54	university	university	NOUN
fnp-5842	222	55	of	of	ADP
fnp-5842	222	56	augsburg	augsburg	PROPN
fnp-5842	222	57	,	,	PUNCT
fnp-5842	222	58	augsburg	augsburg	PROPN
fnp-5842	222	59	,	,	PUNCT
fnp-5842	222	60	germany	germany	PROPN
fnp-5842	222	61	2	2	NUM
fnp-5842	222	62	department	department	NOUN
fnp-5842	222	63	of	of	ADP
fnp-5842	222	64	neuropathology	neuropathology	NOUN
fnp-5842	222	65	,	,	PUNCT
fnp-5842	222	66	pathology	pathology	NOUN
fnp-5842	222	67	,	,	PUNCT
fnp-5842	222	68	medical	medical	ADJ
fnp-5842	222	69	faculty	faculty	NOUN
fnp-5842	222	70	,	,	PUNCT
fnp-5842	222	71	university	university	NOUN
fnp-5842	222	72	of	of	ADP
fnp-5842	222	73	augsburg	augsburg	PROPN
fnp-5842	222	74	,	,	PUNCT
fnp-5842	222	75	augsburg	augsburg	PROPN
fnp-5842	222	76	,	,	PUNCT
fnp-5842	222	77	germany	germany	PROPN
fnp-5842	222	78	3	3	NUM
fnp-5842	222	79	university	university	NOUN
fnp-5842	222	80	hospital	hospital	NOUN
fnp-5842	222	81	ruppin	ruppin	NOUN
fnp-5842	222	82	-	-	PUNCT
fnp-5842	222	83	brandenburg	brandenburg	PROPN
fnp-5842	222	84	,	,	PUNCT
fnp-5842	222	85	institute	institute	NOUN
fnp-5842	222	86	of	of	ADP
fnp-5842	222	87	pathology	pathology	PROPN
fnp-5842	222	88	and	and	CCONJ
fnp-5842	222	89	cytology	cytology	NOUN
fnp-5842	222	90	,	,	PUNCT
fnp-5842	222	91	neuruppin	neuruppin	PROPN
fnp-5842	222	92	,	,	PUNCT
fnp-5842	222	93	germany	germany	PROPN
fnp-5842	222	94	4	4	NUM
fnp-5842	222	95	pathology	pathology	NOUN
fnp-5842	222	96	ingolstadt	ingolstadt	NOUN
fnp-5842	222	97	,	,	PUNCT
fnp-5842	222	98	ingolstadt	ingolstadt	NOUN
fnp-5842	222	99	,	,	PUNCT
fnp-5842	222	100	germany	germany	PROPN
fnp-5842	222	101	5	5	NUM
fnp-5842	222	102	technical	technical	PROPN
fnp-5842	222	103	university	university	PROPN
fnp-5842	222	104	of	of	ADP
fnp-5842	222	105	munich	munich	PROPN
fnp-5842	222	106	,	,	PUNCT
fnp-5842	222	107	school	school	NOUN
fnp-5842	222	108	of	of	ADP
fnp-5842	222	109	medicine	medicine	NOUN
fnp-5842	222	110	and	and	CCONJ
fnp-5842	222	111	health	health	PROPN
fnp-5842	222	112	institute	institute	PROPN
fnp-5842	222	113	of	of	ADP
fnp-5842	222	114	pathology	pathology	PROPN
fnp-5842	222	115	,	,	PUNCT
fnp-5842	222	116	munich	munich	PROPN
fnp-5842	222	117	,	,	PUNCT
fnp-5842	222	118	germany	germany	PROPN
fnp-5842	222	119	6	6	NUM
fnp-5842	222	120	klinikum	klinikum	NOUN
fnp-5842	222	121	ingolstadt	ingolstadt	NOUN
fnp-5842	222	122	,	,	PUNCT
fnp-5842	222	123	department	department	NOUN
fnp-5842	222	124	of	of	ADP
fnp-5842	222	125	neurology	neurology	NOUN
fnp-5842	222	126	,	,	PUNCT
fnp-5842	222	127	ingolstadt	ingolstadt	PROPN
fnp-5842	222	128	,	,	PUNCT
fnp-5842	222	129	germany	germany	PROPN
fnp-5842	222	130	borna	borna	PROPN
fnp-5842	222	131	disease	disease	PROPN
fnp-5842	222	132	virus	virus	NOUN
fnp-5842	222	133	1	1	NUM
fnp-5842	222	134	(	(	PUNCT
fnp-5842	222	135	bodv-1	bodv-1	NOUN
fnp-5842	222	136	)	)	PUNCT
fnp-5842	222	137	causes	cause	VERB
fnp-5842	222	138	fatal	fatal	ADJ
fnp-5842	222	139	encephalitis	encephalitis	NOUN
fnp-5842	222	140	in	in	ADP
fnp-5842	222	141	endemic	endemic	ADJ
fnp-5842	222	142	regions	region	NOUN
fnp-5842	222	143	.	.	PUNCT
fnp-5842	223	1	even	even	ADV
fnp-5842	223	2	if	if	SCONJ
fnp-5842	223	3	there	there	PRON
fnp-5842	223	4	are	be	VERB
fnp-5842	223	5	reports	report	NOUN
fnp-5842	223	6	on	on	ADP
fnp-5842	223	7	spread	spread	NOUN
fnp-5842	223	8	of	of	ADP
fnp-5842	223	9	this	this	DET
fnp-5842	223	10	highly	highly	ADV
fnp-5842	223	11	neurotropic	neurotropic	ADJ
fnp-5842	223	12	virus	virus	NOUN
fnp-5842	223	13	to	to	ADP
fnp-5842	223	14	the	the	DET
fnp-5842	223	15	peripheral	peripheral	ADJ
fnp-5842	223	16	nervous	nervous	ADJ
fnp-5842	223	17	system	system	NOUN
fnp-5842	223	18	,	,	PUNCT
fnp-5842	223	19	there	there	PRON
fnp-5842	223	20	is	be	VERB
fnp-5842	223	21	no	no	DET
fnp-5842	223	22	systematic	systematic	ADJ
fnp-5842	223	23	analysis	analysis	NOUN
fnp-5842	223	24	of	of	ADP
fnp-5842	223	25	the	the	DET
fnp-5842	223	26	virus	virus	NOUN
fnp-5842	223	27	distribution	distribution	NOUN
fnp-5842	223	28	aside	aside	ADV
fnp-5842	223	29	from	from	ADP
fnp-5842	223	30	the	the	DET
fnp-5842	223	31	central	central	ADJ
fnp-5842	223	32	nervous	nervous	ADJ
fnp-5842	223	33	system	system	NOUN
fnp-5842	223	34	yet	yet	ADV
fnp-5842	223	35	.	.	PUNCT
fnp-5842	224	1	we	we	PRON
fnp-5842	224	2	analyzed	analyze	VERB
fnp-5842	224	3	autopsy	autopsy	ADJ
fnp-5842	224	4	material	material	NOUN
fnp-5842	224	5	from	from	ADP
fnp-5842	224	6	four	four	NUM
fnp-5842	224	7	deceased	deceased	ADJ
fnp-5842	224	8	with	with	ADP
fnp-5842	224	9	bodv-1	bodv-1	NOUN
fnp-5842	224	10	infection	infection	NOUN
fnp-5842	224	11	regarding	regard	VERB
fnp-5842	224	12	the	the	DET
fnp-5842	224	13	presence	presence	NOUN
fnp-5842	224	14	of	of	ADP
fnp-5842	224	15	bodv-1	bodv-1	NOUN
fnp-5842	224	16	nucleoprotein	nucleoprotein	NOUN
fnp-5842	224	17	in	in	ADP
fnp-5842	224	18	visceral	visceral	ADJ
fnp-5842	224	19	organs	organ	NOUN
fnp-5842	224	20	(	(	PUNCT
fnp-5842	224	21	including	include	VERB
fnp-5842	224	22	heart	heart	NOUN
fnp-5842	224	23	,	,	PUNCT
fnp-5842	224	24	lung	lung	NOUN
fnp-5842	224	25	,	,	PUNCT
fnp-5842	224	26	liver	liver	NOUN
fnp-5842	224	27	,	,	PUNCT
fnp-5842	224	28	thyroid	thyroid	NOUN
fnp-5842	224	29	gland	gland	NOUN
fnp-5842	224	30	,	,	PUNCT
fnp-5842	224	31	pancreas	pancreas	NOUN
fnp-5842	224	32	,	,	PUNCT
fnp-5842	224	33	stomach	stomach	NOUN
fnp-5842	224	34	)	)	PUNCT
fnp-5842	224	35	with	with	ADP
fnp-5842	224	36	immunohistochemistry	immunohistochemistry	NOUN
fnp-5842	224	37	.	.	PUNCT
fnp-5842	225	1	additionally	additionally	ADV
fnp-5842	225	2	,	,	PUNCT
fnp-5842	225	3	we	we	PRON
fnp-5842	225	4	evaluated	evaluate	VERB
fnp-5842	225	5	the	the	DET
fnp-5842	225	6	tissue	tissue	NOUN
fnp-5842	225	7	morphology	morphology	NOUN
fnp-5842	225	8	considering	consider	VERB
fnp-5842	225	9	local	local	ADJ
fnp-5842	225	10	inflammatory	inflammatory	ADJ
fnp-5842	225	11	reaction	reaction	NOUN
fnp-5842	225	12	,	,	PUNCT
fnp-5842	225	13	which	which	PRON
fnp-5842	225	14	is	be	AUX
fnp-5842	225	15	commonly	commonly	ADV
fnp-5842	225	16	observed	observe	VERB
fnp-5842	225	17	in	in	ADP
fnp-5842	225	18	central	central	ADJ
fnp-5842	225	19	nervous	nervous	ADJ
fnp-5842	225	20	system	system	NOUN
fnp-5842	225	21	and	and	CCONJ
fnp-5842	225	22	contributes	contribute	VERB
fnp-5842	225	23	to	to	ADP
fnp-5842	225	24	the	the	DET
fnp-5842	225	25	fatal	fatal	ADJ
fnp-5842	225	26	outcome	outcome	NOUN
fnp-5842	225	27	.	.	PUNCT
fnp-5842	226	1	bodv-1	bodv-1	PROPN
fnp-5842	226	2	could	could	AUX
fnp-5842	226	3	be	be	AUX
fnp-5842	226	4	shown	show	VERB
fnp-5842	226	5	in	in	ADP
fnp-5842	226	6	small	small	ADJ
fnp-5842	226	7	peripheral	peripheral	ADJ
fnp-5842	226	8	nerves	nerve	NOUN
fnp-5842	226	9	in	in	ADP
fnp-5842	226	10	the	the	DET
fnp-5842	226	11	thyroid	thyroid	NOUN
fnp-5842	226	12	gland	gland	NOUN
fnp-5842	226	13	,	,	PUNCT
fnp-5842	226	14	pancreas	pancreas	NOUN
fnp-5842	226	15	,	,	PUNCT
fnp-5842	226	16	adrenal	adrenal	ADJ
fnp-5842	226	17	glands	gland	NOUN
fnp-5842	226	18	,	,	PUNCT
fnp-5842	226	19	left	leave	VERB
fnp-5842	226	20	side	side	NOUN
fnp-5842	226	21	heart	heart	NOUN
fnp-5842	226	22	and	and	CCONJ
fnp-5842	226	23	in	in	ADP
fnp-5842	226	24	the	the	DET
fnp-5842	226	25	stomach	stomach	NOUN
fnp-5842	226	26	,	,	PUNCT
fnp-5842	226	27	without	without	ADP
fnp-5842	226	28	spread	spread	NOUN
fnp-5842	226	29	outside	outside	ADP
fnp-5842	226	30	the	the	DET
fnp-5842	226	31	nerve	nerve	NOUN
fnp-5842	226	32	structures	structure	NOUN
fnp-5842	226	33	.	.	PUNCT
fnp-5842	227	1	one	one	NUM
fnp-5842	227	2	patient	patient	NOUN
fnp-5842	227	3	was	be	AUX
fnp-5842	227	4	a	a	DET
fnp-5842	227	5	transplant	transplant	NOUN
fnp-5842	227	6	recipient	recipient	NOUN
fnp-5842	227	7	from	from	ADP
fnp-5842	227	8	earliest	early	ADJ
fnp-5842	227	9	reported	report	VERB
fnp-5842	227	10	infection	infection	NOUN
fnp-5842	227	11	cluster	cluster	NOUN
fnp-5842	227	12	and	and	CCONJ
fnp-5842	227	13	showed	show	VERB
fnp-5842	227	14	additional	additional	ADJ
fnp-5842	227	15	infiltration	infiltration	NOUN
fnp-5842	227	16	in	in	ADP
fnp-5842	227	17	peripheral	peripheral	ADJ
fnp-5842	227	18	skeletal	skeletal	ADJ
fnp-5842	227	19	nerves	nerve	NOUN
fnp-5842	227	20	,	,	PUNCT
fnp-5842	227	21	esophagus	esophagus	NOUN
fnp-5842	227	22	,	,	PUNCT
fnp-5842	227	23	mediastinal	mediastinal	ADJ
fnp-5842	227	24	and	and	CCONJ
fnp-5842	227	25	retroperitoneal	retroperitoneal	ADJ
fnp-5842	227	26	adipose	adipose	ADP
fnp-5842	227	27	tissue	tissue	NOUN
fnp-5842	227	28	,	,	PUNCT
fnp-5842	227	29	lungs	lung	NOUN
fnp-5842	227	30	,	,	PUNCT
fnp-5842	227	31	liver	liver	NOUN
fnp-5842	227	32	as	as	ADV
fnp-5842	227	33	well	well	ADV
fnp-5842	227	34	as	as	ADP
fnp-5842	227	35	in	in	ADP
fnp-5842	227	36	the	the	DET
fnp-5842	227	37	implanted	implant	VERB
fnp-5842	227	38	but	but	CCONJ
fnp-5842	227	39	not	not	PART
fnp-5842	227	40	their	their	PRON
fnp-5842	227	41	own	own	ADJ
fnp-5842	227	42	kidney	kidney	NOUN
fnp-5842	227	43	.	.	PUNCT
fnp-5842	228	1	neither	neither	CCONJ
fnp-5842	228	2	inflammatory	inflammatory	ADJ
fnp-5842	228	3	nor	nor	CCONJ
fnp-5842	228	4	any	any	DET
fnp-5842	228	5	other	other	ADJ
fnp-5842	228	6	tissue	tissue	NOUN
fnp-5842	228	7	reaction	reaction	NOUN
fnp-5842	228	8	was	be	AUX
fnp-5842	228	9	observed	observe	VERB
fnp-5842	228	10	.	.	PUNCT
fnp-5842	229	1	in	in	ADP
fnp-5842	229	2	one	one	NUM
fnp-5842	229	3	case	case	NOUN
fnp-5842	229	4	,	,	PUNCT
fnp-5842	229	5	no	no	DET
fnp-5842	229	6	peripheral	peripheral	ADJ
fnp-5842	229	7	spread	spread	NOUN
fnp-5842	229	8	could	could	AUX
fnp-5842	229	9	be	be	AUX
fnp-5842	229	10	shown	show	VERB
fnp-5842	229	11	(	(	PUNCT
fnp-5842	229	12	with	with	ADP
fnp-5842	229	13	also	also	ADV
fnp-5842	229	14	atypical	atypical	ADJ
fnp-5842	229	15	brain	brain	NOUN
fnp-5842	229	16	distribution	distribution	NOUN
fnp-5842	229	17	due	due	ADP
fnp-5842	229	18	to	to	ADP
fnp-5842	229	19	high	high	ADJ
fnp-5842	229	20	-	-	PUNCT
fnp-5842	229	21	dose	dose	NOUN
fnp-5842	229	22	immunosuppression	immunosuppression	NOUN
fnp-5842	229	23	)	)	PUNCT
fnp-5842	229	24	.	.	PUNCT
fnp-5842	230	1	no	no	DET
fnp-5842	230	2	patient	patient	NOUN
fnp-5842	230	3	showed	show	VERB
fnp-5842	230	4	bodv-1	bodv-1	NOUN
fnp-5842	230	5	positivity	positivity	NOUN
fnp-5842	230	6	aside	aside	ADV
fnp-5842	230	7	of	of	ADP
fnp-5842	230	8	the	the	DET
fnp-5842	230	9	peripheral	peripheral	ADJ
fnp-5842	230	10	nerve	nerve	NOUN
fnp-5842	230	11	tissue	tissue	NOUN
fnp-5842	230	12	.	.	PUNCT
fnp-5842	231	1	we	we	PRON
fnp-5842	231	2	confirm	confirm	VERB
fnp-5842	231	3	that	that	SCONJ
fnp-5842	231	4	bodv-1	bodv-1	NOUN
fnp-5842	231	5	spreads	spread	VERB
fnp-5842	231	6	to	to	ADP
fnp-5842	231	7	small	small	ADJ
fnp-5842	231	8	peripheral	peripheral	ADJ
fnp-5842	231	9	nerves	nerve	NOUN
fnp-5842	231	10	,	,	PUNCT
fnp-5842	231	11	pronouncing	pronounce	VERB
fnp-5842	231	12	in	in	ADP
fnp-5842	231	13	organs	organ	NOUN
fnp-5842	231	14	innervated	innervate	VERB
fnp-5842	231	15	by	by	ADP
fnp-5842	231	16	the	the	DET
fnp-5842	231	17	vagus	vagus	NOUN
fnp-5842	231	18	nerve	nerve	NOUN
fnp-5842	231	19	.	.	PUNCT
fnp-5842	232	1	although	although	SCONJ
fnp-5842	232	2	neither	neither	CCONJ
fnp-5842	232	3	specific	specific	ADJ
fnp-5842	232	4	reaction	reaction	NOUN
fnp-5842	232	5	nor	nor	CCONJ
fnp-5842	232	6	local	local	ADJ
fnp-5842	232	7	damage	damage	NOUN
fnp-5842	232	8	was	be	AUX
fnp-5842	232	9	observed	observe	VERB
fnp-5842	232	10	,	,	PUNCT
fnp-5842	232	11	consecutive	consecutive	ADJ
fnp-5842	232	12	autonomic	autonomic	ADJ
fnp-5842	232	13	nerve	nerve	NOUN
fnp-5842	232	14	system	system	NOUN
fnp-5842	232	15	dysregulation	dysregulation	NOUN
fnp-5842	232	16	may	may	AUX
fnp-5842	232	17	occur	occur	VERB
fnp-5842	232	18	in	in	ADP
fnp-5842	232	19	some	some	DET
fnp-5842	232	20	patients	patient	NOUN
fnp-5842	232	21	.	.	PUNCT
fnp-5842	233	1	investigations	investigation	NOUN
fnp-5842	233	2	regarding	regard	VERB
fnp-5842	233	3	alternative	alternative	ADJ
fnp-5842	233	4	clinical	clinical	ADJ
fnp-5842	233	5	presentations	presentation	NOUN
fnp-5842	233	6	apart	apart	ADV
fnp-5842	233	7	from	from	ADP
fnp-5842	233	8	the	the	DET
fnp-5842	233	9	typical	typical	ADJ
fnp-5842	233	10	encephalitis	encephalitis	NOUN
fnp-5842	233	11	should	should	AUX
fnp-5842	233	12	be	be	AUX
fnp-5842	233	13	considered	consider	VERB
fnp-5842	233	14	.	.	PUNCT
fnp-5842	234	1	p18	p18	ADJ
fnp-5842	234	2	free	free	ADJ
fnp-5842	234	3	neuropathol	neuropathol	NOUN
fnp-5842	234	4	5:19:30	5:19:30	NUM
fnp-5842	234	5	global	global	ADJ
fnp-5842	234	6	cerebral	cerebral	ADJ
fnp-5842	234	7	hypoxia	hypoxia	NOUN
fnp-5842	234	8	-	-	PUNCT
fnp-5842	234	9	ischemia	ischemia	NOUN
fnp-5842	234	10	:	:	PUNCT
fnp-5842	234	11	ex	ex	X
fnp-5842	234	12	vivo	vivo	ADJ
fnp-5842	234	13	ultrahigh	ultrahigh	ADJ
fnp-5842	234	14	field	field	NOUN
fnp-5842	234	15	mri	mri	NOUN
fnp-5842	234	16	signals	signal	NOUN
fnp-5842	234	17	correlate	correlate	VERB
fnp-5842	234	18	with	with	ADP
fnp-5842	234	19	differential	differential	ADJ
fnp-5842	234	20	cortical	cortical	ADJ
fnp-5842	234	21	localization	localization	NOUN
fnp-5842	234	22	of	of	ADP
fnp-5842	234	23	microglia	microglia	NOUN
fnp-5842	234	24	and	and	CCONJ
fnp-5842	234	25	gemistocytes	gemistocyte	NOUN
fnp-5842	234	26	characterized	characterize	VERB
fnp-5842	234	27	by	by	ADP
fnp-5842	234	28	chit1	chit1	NOUN
fnp-5842	234	29	and	and	CCONJ
fnp-5842	234	30	chi3l1	chi3l1	NOUN
fnp-5842	234	31	(	(	PUNCT
fnp-5842	234	32	ykl	ykl	NOUN
fnp-5842	234	33	40	40	NUM
fnp-5842	234	34	)	)	PUNCT
fnp-5842	234	35	expression	expression	NOUN
fnp-5842	234	36	deniz	deniz	PROPN
fnp-5842	234	37	yilmazer	yilmazer	NOUN
fnp-5842	234	38	-	-	PUNCT
fnp-5842	234	39	hanke1	hanke1	PROPN
fnp-5842	234	40	,	,	PUNCT
fnp-5842	234	41	elisa	elisa	PROPN
fnp-5842	234	42	tuzzi1	tuzzi1	PROPN
fnp-5842	234	43	,	,	PUNCT
fnp-5842	234	44	najwa	najwa	PROPN
fnp-5842	234	45	ouali	ouali	PROPN
fnp-5842	234	46	alami1	alami1	PROPN
fnp-5842	234	47	,	,	PUNCT
fnp-5842	234	48	lubin	lubin	PROPN
fnp-5842	234	49	fang1	fang1	PROPN
fnp-5842	234	50	,	,	PUNCT
fnp-5842	234	51	sigrid	sigrid	VERB
fnp-5842	234	52	klotz2	klotz2	PROPN
fnp-5842	234	53	,	,	PUNCT
fnp-5842	234	54	ellen	ellen	PROPN
fnp-5842	234	55	gelpi2	gelpi2	PROPN
fnp-5842	234	56	,	,	PUNCT
fnp-5842	234	57	kelly	kelly	PROPN
fnp-5842	234	58	del	del	X
fnp-5842	234	59	tredici1	tredici1	PROPN
fnp-5842	234	60	1	1	NUM
fnp-5842	234	61	clinical	clinical	ADJ
fnp-5842	234	62	neuroanatomy	neuroanatomy	NOUN
fnp-5842	234	63	,	,	PUNCT
fnp-5842	234	64	neurology	neurology	NOUN
fnp-5842	234	65	,	,	PUNCT
fnp-5842	234	66	university	university	NOUN
fnp-5842	234	67	ulm	ulm	NOUN
fnp-5842	234	68	,	,	PUNCT
fnp-5842	234	69	university	university	NOUN
fnp-5842	234	70	hospital	hospital	NOUN
fnp-5842	234	71	ulm	ulm	PROPN
fnp-5842	234	72	,	,	PUNCT
fnp-5842	234	73	ulm	ulm	PROPN
fnp-5842	234	74	,	,	PUNCT
fnp-5842	234	75	germany	germany	PROPN
fnp-5842	234	76	2	2	NUM
fnp-5842	234	77	division	division	NOUN
fnp-5842	234	78	of	of	ADP
fnp-5842	234	79	neuropathology	neuropathology	NOUN
fnp-5842	234	80	and	and	CCONJ
fnp-5842	234	81	neurochemistry	neurochemistry	NOUN
fnp-5842	234	82	,	,	PUNCT
fnp-5842	234	83	department	department	NOUN
fnp-5842	234	84	of	of	ADP
fnp-5842	234	85	neurology	neurology	NOUN
fnp-5842	234	86	,	,	PUNCT
fnp-5842	234	87	medical	medical	ADJ
fnp-5842	234	88	university	university	PROPN
fnp-5842	234	89	of	of	ADP
fnp-5842	234	90	vienna	vienna	PROPN
fnp-5842	234	91	,	,	PUNCT
fnp-5842	234	92	vienna	vienna	PROPN
fnp-5842	234	93	,	,	PUNCT
fnp-5842	234	94	austria	austria	PROPN
fnp-5842	234	95	previously	previously	ADV
fnp-5842	234	96	,	,	PUNCT
fnp-5842	234	97	we	we	PRON
fnp-5842	234	98	have	have	AUX
fnp-5842	234	99	shown	show	VERB
fnp-5842	234	100	in	in	ADP
fnp-5842	234	101	survivors	survivor	NOUN
fnp-5842	234	102	of	of	ADP
fnp-5842	234	103	global	global	ADJ
fnp-5842	234	104	hypoxic	hypoxic	ADJ
fnp-5842	234	105	-	-	PUNCT
fnp-5842	234	106	ischemic	ischemic	ADJ
fnp-5842	234	107	brain	brain	NOUN
fnp-5842	234	108	injury	injury	NOUN
fnp-5842	234	109	(	(	PUNCT
fnp-5842	234	110	hibi	hibi	PROPN
fnp-5842	234	111	)	)	PUNCT
fnp-5842	234	112	that	that	SCONJ
fnp-5842	234	113	the	the	DET
fnp-5842	234	114	neuroinflammationand	neuroinflammationand	ADJ
fnp-5842	234	115	ischemia	ischemia	NOUN
fnp-5842	234	116	-	-	PUNCT
fnp-5842	234	117	related	relate	VERB
fnp-5842	234	118	glial	glial	ADJ
fnp-5842	234	119	markers	marker	NOUN
fnp-5842	234	120	chitotriosidase	chitotriosidase	NOUN
fnp-5842	234	121	1	1	NUM
fnp-5842	234	122	(	(	PUNCT
fnp-5842	234	123	chit1	chit1	PROPN
fnp-5842	234	124	)	)	PUNCT
fnp-5842	234	125	and	and	CCONJ
fnp-5842	234	126	chitinase-3	chitinase-3	NUM
fnp-5842	234	127	-	-	PUNCT
fnp-5842	234	128	like	like	ADJ
fnp-5842	234	129	protein	protein	NOUN
fnp-5842	234	130	1	1	NUM
fnp-5842	234	131	(	(	PUNCT
fnp-5842	234	132	chi3l1	chi3l1	NOUN
fnp-5842	234	133	,	,	PUNCT
fnp-5842	234	134	alias	alias	PROPN
fnp-5842	234	135	ykl-40	ykl-40	PROPN
fnp-5842	234	136	)	)	PUNCT
fnp-5842	234	137	are	be	AUX
fnp-5842	234	138	expressed	express	VERB
fnp-5842	234	139	by	by	ADP
fnp-5842	234	140	microglia	microglia	ADJ
fnp-5842	234	141	and	and	CCONJ
fnp-5842	234	142	astrocytic	astrocytic	ADJ
fnp-5842	234	143	gemistocytes	gemistocyte	NOUN
fnp-5842	234	144	,	,	PUNCT
fnp-5842	234	145	respectively	respectively	ADV
fnp-5842	234	146	(	(	PUNCT
fnp-5842	234	147	yilmazer	yilmazer	NOUN
fnp-5842	234	148	-	-	PUNCT
fnp-5842	234	149	hanke	hanke	PROPN
fnp-5842	234	150	et	et	PROPN
fnp-5842	234	151	al	al	PROPN
fnp-5842	234	152	.	.	PROPN
fnp-5842	234	153	,	,	PUNCT
fnp-5842	234	154	2022	2022	NUM
fnp-5842	234	155	,	,	PUNCT
fnp-5842	234	156	neuroscience	neuroscience	NOUN
fnp-5842	234	157	506:91–11	506:91–11	NUM
fnp-5842	234	158	)	)	PUNCT
fnp-5842	234	159	.	.	PUNCT
fnp-5842	235	1	in	in	ADP
fnp-5842	235	2	the	the	DET
fnp-5842	235	3	current	current	ADJ
fnp-5842	235	4	study	study	NOUN
fnp-5842	235	5	,	,	PUNCT
fnp-5842	235	6	we	we	PRON
fnp-5842	235	7	investigated	investigate	VERB
fnp-5842	235	8	the	the	DET
fnp-5842	235	9	distribution	distribution	NOUN
fnp-5842	235	10	of	of	ADP
fnp-5842	235	11	chit1	chit1	NOUN
fnp-5842	235	12	-	-	PUNCT
fnp-5842	235	13	positive	positive	ADJ
fnp-5842	235	14	microglia	microglia	NOUN
fnp-5842	235	15	and	and	CCONJ
fnp-5842	235	16	chi3l1	chi3l1	NOUN
fnp-5842	235	17	-	-	PUNCT
fnp-5842	235	18	positive	positive	ADJ
fnp-5842	235	19	gemistocytes	gemistocyte	NOUN
fnp-5842	235	20	in	in	ADP
fnp-5842	235	21	the	the	DET
fnp-5842	235	22	cerebral	cerebral	ADJ
fnp-5842	235	23	cortex	cortex	NOUN
fnp-5842	235	24	after	after	ADP
fnp-5842	235	25	hibi	hibi	NOUN
fnp-5842	235	26	.	.	PUNCT
fnp-5842	236	1	tissue	tissue	NOUN
fnp-5842	236	2	from	from	ADP
fnp-5842	236	3	hibi	hibi	PROPN
fnp-5842	236	4	cases	case	NOUN
fnp-5842	236	5	was	be	AUX
fnp-5842	236	6	scanned	scan	VERB
fnp-5842	236	7	using	use	VERB
fnp-5842	236	8	high	high	ADJ
fnp-5842	236	9	-	-	PUNCT
fnp-5842	236	10	resolution	resolution	NOUN
fnp-5842	236	11	ultrahigh	ultrahigh	ADJ
fnp-5842	236	12	field	field	NOUN
fnp-5842	236	13	mri	mri	NOUN
fnp-5842	236	14	(	(	PUNCT
fnp-5842	236	15	uhf	uhf	PROPN
fnp-5842	236	16	-	-	PUNCT
fnp-5842	236	17	mri	mri	NOUN
fnp-5842	236	18	)	)	PUNCT
fnp-5842	236	19	with	with	ADP
fnp-5842	236	20	ex	ex	PRON
fnp-5842	236	21	vivo	vivo	NOUN
fnp-5842	236	22	t1w	t1w	NOUN
fnp-5842	236	23	,	,	PUNCT
fnp-5842	236	24	t2w	t2w	PUNCT
fnp-5842	236	25	and	and	CCONJ
fnp-5842	236	26	t2*w	t2*w	PROPN
fnp-5842	236	27	sequences	sequence	NOUN
fnp-5842	236	28	.	.	PUNCT
fnp-5842	237	1	chit1	chit1	NOUN
fnp-5842	237	2	and	and	CCONJ
fnp-5842	237	3	chi3l1	chi3l1	NOUN
fnp-5842	237	4	expression	expression	NOUN
fnp-5842	237	5	was	be	AUX
fnp-5842	237	6	compared	compare	VERB
fnp-5842	237	7	to	to	ADP
fnp-5842	237	8	changes	change	NOUN
fnp-5842	237	9	in	in	ADP
fnp-5842	237	10	microglial	microglial	ADJ
fnp-5842	237	11	(	(	PUNCT
fnp-5842	237	12	e.g.	e.g.	ADV
fnp-5842	237	13	,	,	PUNCT
fnp-5842	237	14	iba1	iba1	PROPN
fnp-5842	237	15	,	,	PUNCT
fnp-5842	237	16	cd68	cd68	PROPN
fnp-5842	237	17	)	)	PUNCT
fnp-5842	237	18	and	and	CCONJ
fnp-5842	237	19	astrocytic	astrocytic	ADJ
fnp-5842	237	20	(	(	PUNCT
fnp-5842	237	21	e.g.	e.g.	ADJ
fnp-5842	237	22	,	,	PUNCT
fnp-5842	237	23	gfap	gfap	ADJ
fnp-5842	237	24	)	)	PUNCT
fnp-5842	237	25	markers	marker	NOUN
fnp-5842	237	26	using	use	VERB
fnp-5842	237	27	immunohistochemistry	immunohistochemistry	NOUN
fnp-5842	237	28	and	and	CCONJ
fnp-5842	237	29	multiple	multiple	ADJ
fnp-5842	237	30	-	-	PUNCT
fnp-5842	237	31	label	label	NOUN
fnp-5842	237	32	immunofluorescence	immunofluorescence	NOUN
fnp-5842	237	33	.	.	PUNCT
fnp-5842	238	1	results	result	NOUN
fnp-5842	238	2	indicated	indicate	VERB
fnp-5842	238	3	altered	altered	ADJ
fnp-5842	238	4	mri	mri	NOUN
fnp-5842	238	5	signals	signal	NOUN
fnp-5842	238	6	in	in	ADP
fnp-5842	238	7	different	different	ADJ
fnp-5842	238	8	cortical	cortical	ADJ
fnp-5842	238	9	layers	layer	NOUN
fnp-5842	238	10	.	.	PUNCT
fnp-5842	239	1	these	these	DET
fnp-5842	239	2	altered	alter	VERB
fnp-5842	239	3	mri	mri	NOUN
fnp-5842	239	4	signals	signal	NOUN
fnp-5842	239	5	correlated	correlate	VERB
fnp-5842	239	6	with	with	ADP
fnp-5842	239	7	severe	severe	ADJ
fnp-5842	239	8	neuronal	neuronal	ADJ
fnp-5842	239	9	cell	cell	NOUN
fnp-5842	239	10	loss	loss	NOUN
fnp-5842	239	11	,	,	PUNCT
fnp-5842	239	12	enhanced	enhance	VERB
fnp-5842	239	13	densities	density	NOUN
fnp-5842	239	14	of	of	ADP
fnp-5842	239	15	rounded	rounded	ADJ
fnp-5842	239	16	chit1	chit1	NOUN
fnp-5842	239	17	-	-	PUNCT
fnp-5842	239	18	positive	positive	ADJ
fnp-5842	239	19	microglia	microglia	NOUN
fnp-5842	239	20	in	in	ADP
fnp-5842	239	21	deep	deep	ADJ
fnp-5842	239	22	cortical	cortical	ADJ
fnp-5842	239	23	layers	layer	NOUN
fnp-5842	239	24	,	,	PUNCT
fnp-5842	239	25	and	and	CCONJ
fnp-5842	239	26	the	the	DET
fnp-5842	239	27	emergence	emergence	NOUN
fnp-5842	239	28	of	of	ADP
fnp-5842	239	29	chi3l1	chi3l1	NOUN
fnp-5842	239	30	-	-	PUNCT
fnp-5842	239	31	positive	positive	ADJ
fnp-5842	239	32	gemistocytes	gemistocyte	NOUN
fnp-5842	239	33	,	,	PUNCT
fnp-5842	239	34	which	which	PRON
fnp-5842	239	35	populated	populate	VERB
fnp-5842	239	36	superficial	superficial	ADJ
fnp-5842	239	37	cortical	cortical	ADJ
fnp-5842	239	38	layers	layer	NOUN
fnp-5842	239	39	and	and	CCONJ
fnp-5842	239	40	the	the	DET
fnp-5842	239	41	juxtacortical	juxtacortical	ADJ
fnp-5842	239	42	boundary	boundary	NOUN
fnp-5842	239	43	.	.	PUNCT
fnp-5842	240	1	further	further	ADJ
fnp-5842	240	2	analyses	analysis	NOUN
fnp-5842	240	3	revealed	reveal	VERB
fnp-5842	240	4	that	that	SCONJ
fnp-5842	240	5	chit1	chit1	NOUN
fnp-5842	240	6	-	-	PUNCT
fnp-5842	240	7	positive	positive	ADJ
fnp-5842	240	8	microglia	microglia	NOUN
fnp-5842	240	9	aggregated	aggregate	VERB
fnp-5842	240	10	around	around	ADP
fnp-5842	240	11	microvessels	microvessel	NOUN
fnp-5842	240	12	of	of	ADP
fnp-5842	240	13	deep	deep	ADJ
fnp-5842	240	14	cortical	cortical	ADJ
fnp-5842	240	15	layers	layer	NOUN
fnp-5842	240	16	.	.	PUNCT
fnp-5842	241	1	in	in	ADP
fnp-5842	241	2	conclusion	conclusion	NOUN
fnp-5842	241	3	,	,	PUNCT
fnp-5842	241	4	altered	alter	VERB
fnp-5842	241	5	cortical	cortical	ADJ
fnp-5842	241	6	mri	mri	NOUN
fnp-5842	241	7	signals	signal	NOUN
fnp-5842	241	8	that	that	PRON
fnp-5842	241	9	reflect	reflect	VERB
fnp-5842	241	10	the	the	DET
fnp-5842	241	11	cortical	cortical	ADJ
fnp-5842	241	12	damage	damage	NOUN
fnp-5842	241	13	as	as	ADV
fnp-5842	241	14	well	well	ADV
fnp-5842	241	15	as	as	ADP
fnp-5842	241	16	chit1and	chit1and	ADP
fnp-5842	241	17	chi3l1	chi3l1	NOUN
fnp-5842	241	18	-	-	PUNCT
fnp-5842	241	19	positive	positive	ADJ
fnp-5842	241	20	glial	glial	ADJ
fnp-5842	241	21	cell	cell	NOUN
fnp-5842	241	22	pathology	pathology	NOUN
fnp-5842	241	23	with	with	ADP
fnp-5842	241	24	a	a	DET
fnp-5842	241	25	differential	differential	ADJ
fnp-5842	241	26	cortical	cortical	ADJ
fnp-5842	241	27	distribution	distribution	NOUN
fnp-5842	241	28	could	could	AUX
fnp-5842	241	29	be	be	AUX
fnp-5842	241	30	a	a	DET
fnp-5842	241	31	valuable	valuable	ADJ
fnp-5842	241	32	in	in	ADP
fnp-5842	241	33	vivo	vivo	NOUN
fnp-5842	241	34	biomarker	biomarker	NOUN
fnp-5842	241	35	for	for	ADP
fnp-5842	241	36	monitoring	monitor	VERB
fnp-5842	241	37	the	the	DET
fnp-5842	241	38	outcome	outcome	NOUN
fnp-5842	241	39	of	of	ADP
fnp-5842	241	40	global	global	ADJ
fnp-5842	241	41	hibi	hibi	PROPN
fnp-5842	241	42	and	and	CCONJ
fnp-5842	241	43	for	for	ADP
fnp-5842	241	44	determining	determine	VERB
fnp-5842	241	45	the	the	DET
fnp-5842	241	46	prognosis	prognosis	NOUN
fnp-5842	241	47	of	of	ADP
fnp-5842	241	48	long	long	ADJ
fnp-5842	241	49	-	-	PUNCT
fnp-5842	241	50	term	term	NOUN
fnp-5842	241	51	hibi	hibi	NOUN
fnp-5842	241	52	survivors	survivor	NOUN
fnp-5842	241	53	.	.	PUNCT
fnp-5842	242	1	iii	iii	X
fnp-5842	242	2	.	.	PROPN
fnp-5842	242	3	muscle	muscle	PROPN
fnp-5842	242	4	/	/	SYM
fnp-5842	242	5	nerv	nerv	PROPN
fnp-5842	242	6	p19	p19	VERB
fnp-5842	242	7	free	free	ADJ
fnp-5842	242	8	neuropathol	neuropathol	NOUN
fnp-5842	242	9	5:19:31	5:19:31	NUM
fnp-5842	242	10	adipo	adipo	ADJ
fnp-5842	242	11	-	-	PUNCT
fnp-5842	242	12	glial	glial	ADJ
fnp-5842	242	13	signaling	signal	VERB
fnp-5842	242	14	mediates	mediate	NOUN
fnp-5842	242	15	metabolic	metabolic	NOUN
fnp-5842	242	16	adaptation	adaptation	NOUN
fnp-5842	242	17	in	in	ADP
fnp-5842	242	18	peripheral	peripheral	ADJ
fnp-5842	242	19	nerve	nerve	NOUN
fnp-5842	242	20	regeneration	regeneration	NOUN
fnp-5842	242	21	v.k	v.k	PROPN
fnp-5842	242	22	.	.	PROPN
fnp-5842	242	23	sundaram1	sundaram1	PROPN
fnp-5842	242	24	,	,	PUNCT
fnp-5842	242	25	v.	v.	PROPN
fnp-5842	242	26	schütza2	schütza2	PROPN
fnp-5842	242	27	,	,	PUNCT
fnp-5842	242	28	n.	n.	PROPN
fnp-5842	242	29	schröter2	schröter2	PROPN
fnp-5842	242	30	,	,	PUNCT
fnp-5842	242	31	e.	e.	PROPN
fnp-5842	242	32	ernst	ernst	PROPN
fnp-5842	242	33	sanchez2	sanchez2	PROPN
fnp-5842	242	34	,	,	PUNCT
fnp-5842	242	35	a.	a.	PROPN
fnp-5842	242	36	backhaus2	backhaus2	PROPN
fnp-5842	242	37	,	,	PUNCT
fnp-5842	242	38	a.	a.	PROPN
fnp-5842	242	39	bilsing2	bilsing2	PROPN
fnp-5842	242	40	,	,	PUNCT
fnp-5842	242	41	l.	l.	PROPN
fnp-5842	242	42	joneck2	joneck2	PROPN
fnp-5842	242	43	,	,	PUNCT
fnp-5842	242	44	a.	a.	NOUN
fnp-5842	242	45	seelbach1	seelbach1	PROPN
fnp-5842	242	46	,	,	PUNCT
fnp-5842	242	47	jose	jose	PROPN
fnp-5842	242	48	a	a	DET
fnp-5842	242	49	gomez	gomez	PROPN
fnp-5842	242	50	-	-	PUNCT
fnp-5842	242	51	sanchez	sanchez	PROPN
fnp-5842	242	52	3	3	NUM
fnp-5842	242	53	,	,	PUNCT
fnp-5842	242	54	d.	d.	PROPN
fnp-5842	242	55	akkermann1	akkermann1	PROPN
fnp-5842	242	56	,	,	PUNCT
fnp-5842	242	57	t.	t.	PROPN
fnp-5842	242	58	kungl2	kungl2	PROPN
fnp-5842	242	59	,	,	PUNCT
fnp-5842	242	60	m.	m.	NOUN
fnp-5842	242	61	ost2	ost2	PROPN
fnp-5842	242	62	,	,	PUNCT
fnp-5842	242	63	peter	peter	PROPN
fnp-5842	242	64	arthur	arthur	PROPN
fnp-5842	242	65	-	-	PUNCT
fnp-5842	242	66	farraj4	farraj4	PROPN
fnp-5842	242	67	,	,	PUNCT
fnp-5842	242	68	r.	r.	PROPN
fnp-5842	242	69	stassart1	stassart1	PROPN
fnp-5842	242	70	,	,	PUNCT
fnp-5842	242	71	r.	r.	PROPN
fnp-5842	242	72	fledrich2	fledrich2	PROPN
fnp-5842	242	73	1	1	NUM
fnp-5842	242	74	paul	paul	PROPN
fnp-5842	242	75	flechsig	flechsig	PROPN
fnp-5842	242	76	institute	institute	PROPN
fnp-5842	242	77	center	center	PROPN
fnp-5842	242	78	of	of	ADP
fnp-5842	242	79	neuropathology	neuropathology	NOUN
fnp-5842	242	80	and	and	CCONJ
fnp-5842	242	81	brain	brain	NOUN
fnp-5842	242	82	research	research	NOUN
fnp-5842	242	83	,	,	PUNCT
fnp-5842	242	84	leipzig	leipzig	PROPN
fnp-5842	242	85	university	university	PROPN
fnp-5842	242	86	,	,	PUNCT
fnp-5842	242	87	leipzig	leipzig	PROPN
fnp-5842	242	88	,	,	PUNCT
fnp-5842	242	89	germany	germany	PROPN
fnp-5842	242	90	2	2	NUM
fnp-5842	242	91	institute	institute	PROPN
fnp-5842	242	92	of	of	ADP
fnp-5842	242	93	anatomy	anatomy	PROPN
fnp-5842	242	94	,	,	PUNCT
fnp-5842	242	95	leipzig	leipzig	PROPN
fnp-5842	242	96	university	university	PROPN
fnp-5842	242	97	,	,	PUNCT
fnp-5842	242	98	leipzig	leipzig	PROPN
fnp-5842	242	99	,	,	PUNCT
fnp-5842	242	100	germany	germany	PROPN
fnp-5842	242	101	3	3	NUM
fnp-5842	242	102	instituto	instituto	PROPN
fnp-5842	242	103	de	de	PROPN
fnp-5842	242	104	investigación	investigación	PROPN
fnp-5842	242	105	sanitaria	sanitaria	PROPN
fnp-5842	242	106	y	y	PROPN
fnp-5842	242	107	biomédica	biomédica	PROPN
fnp-5842	242	108	de	de	PROPN
fnp-5842	242	109	alicante	alicante	PROPN
fnp-5842	242	110	(	(	PUNCT
fnp-5842	242	111	isabial	isabial	ADJ
fnp-5842	242	112	)	)	PUNCT
fnp-5842	242	113	,	,	PUNCT
fnp-5842	242	114	alicante	alicante	PROPN
fnp-5842	242	115	,	,	PUNCT
fnp-5842	242	116	spain	spain	PROPN
fnp-5842	242	117	;	;	PUNCT
fnp-5842	242	118	instituto	instituto	PROPN
fnp-5842	242	119	de	de	PROPN
fnp-5842	242	120	neurociencias	neurociencias	PROPN
fnp-5842	242	121	csic	csic	PROPN
fnp-5842	242	122	-	-	PUNCT
fnp-5842	242	123	umh	umh	PROPN
fnp-5842	242	124	,	,	PUNCT
fnp-5842	242	125	san	san	PROPN
fnp-5842	242	126	juan	juan	PROPN
fnp-5842	242	127	de	de	PROPN
fnp-5842	242	128	alicante	alicante	PROPN
fnp-5842	242	129	,	,	PUNCT
fnp-5842	242	130	spain	spain	PROPN
fnp-5842	242	131	4	4	NUM
fnp-5842	242	132	john	john	PROPN
fnp-5842	242	133	van	van	PROPN
fnp-5842	242	134	geest	geest	PROPN
fnp-5842	242	135	centre	centre	PROPN
fnp-5842	242	136	for	for	ADP
fnp-5842	242	137	brain	brain	NOUN
fnp-5842	242	138	repair	repair	NOUN
fnp-5842	242	139	,	,	PUNCT
fnp-5842	242	140	department	department	NOUN
fnp-5842	242	141	of	of	ADP
fnp-5842	242	142	clinical	clinical	ADJ
fnp-5842	242	143	neurosciences	neuroscience	NOUN
fnp-5842	242	144	,	,	PUNCT
fnp-5842	242	145	university	university	NOUN
fnp-5842	242	146	of	of	ADP
fnp-5842	242	147	cambridge	cambridge	PROPN
fnp-5842	242	148	,	,	PUNCT
fnp-5842	242	149	cambridge	cambridge	PROPN
fnp-5842	242	150	cb2	cb2	PROPN
fnp-5842	242	151	0py	0py	PROPN
fnp-5842	242	152	,	,	PUNCT
fnp-5842	242	153	uk	uk	PROPN
fnp-5842	242	154	the	the	DET
fnp-5842	242	155	peripheral	peripheral	ADJ
fnp-5842	242	156	nervous	nervous	ADJ
fnp-5842	242	157	system	system	NOUN
fnp-5842	242	158	exhibits	exhibit	VERB
fnp-5842	242	159	an	an	DET
fnp-5842	242	160	impressive	impressive	ADJ
fnp-5842	242	161	potential	potential	NOUN
fnp-5842	242	162	to	to	PART
fnp-5842	242	163	regenerate	regenerate	VERB
fnp-5842	242	164	following	follow	VERB
fnp-5842	242	165	acute	acute	ADJ
fnp-5842	242	166	nerve	nerve	NOUN
fnp-5842	242	167	injury	injury	NOUN
fnp-5842	242	168	.	.	PUNCT
fnp-5842	243	1	however	however	ADV
fnp-5842	243	2	,	,	PUNCT
fnp-5842	243	3	complete	complete	ADJ
fnp-5842	243	4	functional	functional	ADJ
fnp-5842	243	5	recovery	recovery	NOUN
fnp-5842	243	6	is	be	AUX
fnp-5842	243	7	uncommon	uncommon	ADJ
fnp-5842	243	8	and	and	CCONJ
fnp-5842	243	9	heavily	heavily	ADV
fnp-5842	243	10	relies	rely	VERB
fnp-5842	243	11	on	on	ADP
fnp-5842	243	12	peripheral	peripheral	ADJ
fnp-5842	243	13	nerve	nerve	NOUN
fnp-5842	243	14	schwann	schwann	PROPN
fnp-5842	243	15	cells	cell	NOUN
fnp-5842	243	16	,	,	PUNCT
fnp-5842	243	17	which	which	PRON
fnp-5842	243	18	orchestrate	orchestrate	VERB
fnp-5842	243	19	both	both	CCONJ
fnp-5842	243	20	the	the	DET
fnp-5842	243	21	degradation	degradation	NOUN
fnp-5842	243	22	and	and	CCONJ
fnp-5842	243	23	re	re	NOUN
fnp-5842	243	24	-	-	NOUN
fnp-5842	243	25	synthesis	synthesis	NOUN
fnp-5842	243	26	of	of	ADP
fnp-5842	243	27	myelin	myelin	NOUN
fnp-5842	243	28	while	while	SCONJ
fnp-5842	243	29	also	also	ADV
fnp-5842	243	30	supporting	support	VERB
fnp-5842	243	31	axonal	axonal	ADJ
fnp-5842	243	32	regrowth	regrowth	NOUN
fnp-5842	243	33	.	.	PUNCT
fnp-5842	244	1	these	these	DET
fnp-5842	244	2	cellular	cellular	ADJ
fnp-5842	244	3	processes	process	NOUN
fnp-5842	244	4	elicit	elicit	VERB
fnp-5842	244	5	a	a	DET
fnp-5842	244	6	substantial	substantial	ADJ
fnp-5842	244	7	metabolic	metabolic	NOUN
fnp-5842	244	8	demand	demand	NOUN
fnp-5842	244	9	and	and	CCONJ
fnp-5842	244	10	the	the	DET
fnp-5842	244	11	exact	exact	ADJ
fnp-5842	244	12	mechanisms	mechanism	NOUN
fnp-5842	244	13	by	by	ADP
fnp-5842	244	14	which	which	PRON
fnp-5842	244	15	schwann	schwann	PROPN
fnp-5842	244	16	cells	cell	NOUN
fnp-5842	244	17	cater	cater	VERB
fnp-5842	244	18	to	to	ADP
fnp-5842	244	19	the	the	DET
fnp-5842	244	20	high	high	ADJ
fnp-5842	244	21	metabolic	metabolic	NOUN
fnp-5842	244	22	demands	demand	NOUN
fnp-5842	244	23	of	of	ADP
fnp-5842	244	24	nerve	nerve	NOUN
fnp-5842	244	25	repair	repair	NOUN
fnp-5842	244	26	are	be	AUX
fnp-5842	244	27	still	still	ADV
fnp-5842	244	28	not	not	PART
fnp-5842	244	29	well	well	ADV
fnp-5842	244	30	understood	understand	VERB
fnp-5842	244	31	.	.	PUNCT
fnp-5842	245	1	in	in	ADP
fnp-5842	245	2	this	this	DET
fnp-5842	245	3	study	study	NOUN
fnp-5842	245	4	,	,	PUNCT
fnp-5842	245	5	we	we	PRON
fnp-5842	245	6	demonstrate	demonstrate	VERB
fnp-5842	245	7	that	that	SCONJ
fnp-5842	245	8	nerve	nerve	NOUN
fnp-5842	245	9	injury	injury	NOUN
fnp-5842	245	10	triggers	trigger	NOUN
fnp-5842	245	11	signaling	signal	VERB
fnp-5842	245	12	from	from	ADP
fnp-5842	245	13	adipocytes	adipocyte	NOUN
fnp-5842	245	14	to	to	ADP
fnp-5842	245	15	glial	glial	ADJ
fnp-5842	245	16	cells	cell	NOUN
fnp-5842	245	17	and	and	CCONJ
fnp-5842	245	18	we	we	PRON
fnp-5842	245	19	identify	identify	VERB
fnp-5842	245	20	the	the	DET
fnp-5842	245	21	adipokine	adipokine	ADJ
fnp-5842	245	22	,	,	PUNCT
fnp-5842	245	23	leptin	leptin	NOUN
fnp-5842	245	24	,	,	PUNCT
fnp-5842	245	25	as	as	ADP
fnp-5842	245	26	a	a	DET
fnp-5842	245	27	key	key	ADJ
fnp-5842	245	28	regulator	regulator	NOUN
fnp-5842	245	29	of	of	ADP
fnp-5842	245	30	glial	glial	ADJ
fnp-5842	245	31	metabolic	metabolic	NOUN
fnp-5842	245	32	adaptation	adaptation	NOUN
fnp-5842	245	33	during	during	ADP
fnp-5842	245	34	regeneration	regeneration	NOUN
fnp-5842	245	35	.	.	PUNCT
fnp-5842	246	1	using	use	VERB
fnp-5842	246	2	conditional	conditional	ADJ
fnp-5842	246	3	mutagenesis	mutagenesis	NOUN
fnp-5842	246	4	in	in	ADP
fnp-5842	246	5	mice	mouse	NOUN
fnp-5842	246	6	,	,	PUNCT
fnp-5842	246	7	we	we	PRON
fnp-5842	246	8	demonstrate	demonstrate	VERB
fnp-5842	246	9	that	that	SCONJ
fnp-5842	246	10	leptin	leptin	NOUN
fnp-5842	246	11	receptor	receptor	NOUN
fnp-5842	246	12	ablation	ablation	NOUN
fnp-5842	246	13	in	in	ADP
fnp-5842	246	14	schwann	schwann	PROPN
fnp-5842	246	15	cells	cell	NOUN
fnp-5842	246	16	or	or	CCONJ
fnp-5842	246	17	leptin	leptin	NOUN
fnp-5842	246	18	ablation	ablation	NOUN
fnp-5842	246	19	in	in	ADP
fnp-5842	246	20	adipocytes	adipocyte	NOUN
fnp-5842	246	21	renders	render	VERB
fnp-5842	246	22	a	a	DET
fnp-5842	246	23	congruent	congruent	ADJ
fnp-5842	246	24	phenotype	phenotype	NOUN
fnp-5842	246	25	characterized	characterize	VERB
fnp-5842	246	26	by	by	ADP
fnp-5842	246	27	abrogated	abrogate	VERB
fnp-5842	246	28	injury	injury	NOUN
fnp-5842	246	29	-	-	PUNCT
fnp-5842	246	30	specific	specific	ADJ
fnp-5842	246	31	catabolic	catabolic	NOUN
fnp-5842	246	32	processes	process	NOUN
fnp-5842	246	33	such	such	ADJ
fnp-5842	246	34	as	as	ADP
fnp-5842	246	35	myelin	myelin	NOUN
fnp-5842	246	36	autophagy	autophagy	NOUN
fnp-5842	246	37	and	and	CCONJ
fnp-5842	246	38	mitochondrial	mitochondrial	ADJ
fnp-5842	246	39	respiration	respiration	NOUN
fnp-5842	246	40	in	in	ADP
fnp-5842	246	41	schwann	schwann	PROPN
fnp-5842	246	42	cells	cell	NOUN
fnp-5842	246	43	during	during	ADP
fnp-5842	246	44	nerve	nerve	NOUN
fnp-5842	246	45	repair	repair	NOUN
fnp-5842	246	46	.	.	PUNCT
fnp-5842	247	1	our	our	PRON
fnp-5842	247	2	research	research	NOUN
fnp-5842	247	3	thus	thus	ADV
fnp-5842	247	4	proposes	propose	VERB
fnp-5842	247	5	a	a	DET
fnp-5842	247	6	model	model	NOUN
fnp-5842	247	7	wherein	wherein	ADJ
fnp-5842	247	8	acute	acute	PROPN
fnp-5842	247	9	nerve	nerve	NOUN
fnp-5842	247	10	injury	injury	NOUN
fnp-5842	247	11	initiates	initiate	VERB
fnp-5842	247	12	an	an	DET
fnp-5842	247	13	adipo	adipo	ADJ
fnp-5842	247	14	-	-	PUNCT
fnp-5842	247	15	glial	glial	ADJ
fnp-5842	247	16	communication	communication	NOUN
fnp-5842	247	17	that	that	PRON
fnp-5842	247	18	can	can	AUX
fnp-5842	247	19	be	be	AUX
fnp-5842	247	20	therapeutically	therapeutically	ADV
fnp-5842	247	21	targeted	target	VERB
fnp-5842	247	22	to	to	PART
fnp-5842	247	23	modulate	modulate	VERB
fnp-5842	247	24	glial	glial	ADJ
fnp-5842	247	25	metabolism	metabolism	NOUN
fnp-5842	247	26	,	,	PUNCT
fnp-5842	247	27	ensuring	ensure	VERB
fnp-5842	247	28	sufficient	sufficient	ADJ
fnp-5842	247	29	energy	energy	NOUN
fnp-5842	247	30	for	for	ADP
fnp-5842	247	31	effective	effective	ADJ
fnp-5842	247	32	nerve	nerve	NOUN
fnp-5842	247	33	repair	repair	NOUN
fnp-5842	247	34	.	.	PUNCT
fnp-5842	248	1	iv	iv	X
fnp-5842	248	2	.	.	PUNCT
fnp-5842	248	3	neurodegeneration	neurodegeneration	NOUN
fnp-5842	248	4	p20	p20	NOUN
fnp-5842	248	5	free	free	ADJ
fnp-5842	248	6	neuropathol	neuropathol	NOUN
fnp-5842	248	7	5:19:32	5:19:32	NUM
fnp-5842	248	8	alpha	alpha	NOUN
fnp-5842	248	9	-	-	PUNCT
fnp-5842	248	10	synuclein	synuclein	NOUN
fnp-5842	248	11	co	co	NOUN
fnp-5842	248	12	-	-	NOUN
fnp-5842	248	13	pathology	pathology	NOUN
fnp-5842	248	14	in	in	ADP
fnp-5842	248	15	alzheimer	alzheimer	PROPN
fnp-5842	248	16	’s	’s	PART
fnp-5842	248	17	disease	disease	NOUN
fnp-5842	248	18	drives	drive	VERB
fnp-5842	249	1	tau	tau	PROPN
fnp-5842	249	2	accumulation	accumulation	NOUN
fnp-5842	249	3	felix	felix	PROPN
fnp-5842	249	4	l.	l.	PROPN
fnp-5842	249	5	struebing1,2	struebing1,2	PROPN
fnp-5842	249	6	,	,	PUNCT
fnp-5842	249	7	teodoro	teodoro	PROPN
fnp-5842	249	8	de	de	X
fnp-5842	249	9	vecchi1,2	vecchi1,2	PROPN
fnp-5842	249	10	,	,	PUNCT
fnp-5842	249	11	jeannine	jeannine	PROPN
fnp-5842	249	12	widmann1,2	widmann1,2	PROPN
fnp-5842	249	13	,	,	PUNCT
fnp-5842	249	14	xiaoxuan	xiaoxuan	PROPN
fnp-5842	249	15	song1,2	song1,2	PROPN
fnp-5842	249	16	,	,	PUNCT
fnp-5842	249	17	federico	federico	PROPN
fnp-5842	249	18	fierli1,2	fierli1,2	PROPN
fnp-5842	249	19	,	,	PUNCT
fnp-5842	249	20	viktoria	viktoria	PROPN
fnp-5842	249	21	ruf1,2	ruf1,2	PROPN
fnp-5842	249	22	,	,	PUNCT
fnp-5842	249	23	qilin	qilin	PROPN
fnp-5842	249	24	tang2,4	tang2,4	PROPN
fnp-5842	249	25	,	,	PUNCT
fnp-5842	249	26	thomas	thomas	PROPN
fnp-5842	249	27	arzberger1	arzberger1	PROPN
fnp-5842	249	28	,	,	PUNCT
fnp-5842	249	29	sigrun	sigrun	PROPN
fnp-5842	249	30	roeber1	roeber1	PROPN
fnp-5842	249	31	,	,	PUNCT
fnp-5842	249	32	thomas	thomas	PROPN
fnp-5842	249	33	koeglsperger2,4	koeglsperger2,4	PROPN
fnp-5842	249	34	,	,	PUNCT
fnp-5842	249	35	otto	otto	PROPN
fnp-5842	249	36	windl1	windl1	PROPN
fnp-5842	249	37	,	,	PUNCT
fnp-5842	249	38	christian	christian	PROPN
fnp-5842	249	39	haass2,3	haass2,3	PROPN
fnp-5842	249	40	,	,	PUNCT
fnp-5842	249	41	juliane	juliane	PROPN
fnp-5842	249	42	winkelmann3	winkelmann3	PROPN
fnp-5842	249	43	,	,	PUNCT
fnp-5842	249	44	jochen	jochen	PROPN
fnp-5842	249	45	herms1,2,3	herms1,2,3	PROPN
fnp-5842	249	46	1	1	NUM
fnp-5842	249	47	center	center	NOUN
fnp-5842	249	48	for	for	ADP
fnp-5842	249	49	neuropathology	neuropathology	NOUN
fnp-5842	249	50	and	and	CCONJ
fnp-5842	249	51	prion	prion	NOUN
fnp-5842	249	52	research	research	NOUN
fnp-5842	249	53	,	,	PUNCT
fnp-5842	249	54	ludwig	ludwig	PROPN
fnp-5842	249	55	maximilian	maximilian	PROPN
fnp-5842	249	56	university	university	PROPN
fnp-5842	249	57	of	of	ADP
fnp-5842	249	58	munich	munich	PROPN
fnp-5842	249	59	,	,	PUNCT
fnp-5842	249	60	munich	munich	PROPN
fnp-5842	249	61	,	,	PUNCT
fnp-5842	249	62	germany	germany	PROPN
fnp-5842	249	63	2	2	NUM
fnp-5842	249	64	german	german	ADJ
fnp-5842	249	65	center	center	NOUN
fnp-5842	249	66	for	for	ADP
fnp-5842	249	67	neurodegenerative	neurodegenerative	ADJ
fnp-5842	249	68	diseases	disease	NOUN
fnp-5842	249	69	(	(	PUNCT
fnp-5842	249	70	dzne	dzne	NOUN
fnp-5842	249	71	)	)	PUNCT
fnp-5842	249	72	,	,	PUNCT
fnp-5842	249	73	munich	munich	PROPN
fnp-5842	249	74	,	,	PUNCT
fnp-5842	249	75	germany	germany	PROPN
fnp-5842	249	76	3	3	NUM
fnp-5842	249	77	munich	munich	PROPN
fnp-5842	249	78	cluster	cluster	NOUN
fnp-5842	249	79	of	of	ADP
fnp-5842	249	80	systems	system	NOUN
fnp-5842	249	81	neurology	neurology	NOUN
fnp-5842	249	82	(	(	PUNCT
fnp-5842	249	83	synergy	synergy	NOUN
fnp-5842	249	84	)	)	PUNCT
fnp-5842	249	85	,	,	PUNCT
fnp-5842	249	86	munich	munich	PROPN
fnp-5842	249	87	,	,	PUNCT
fnp-5842	249	88	germany	germany	PROPN
fnp-5842	249	89	4	4	NUM
fnp-5842	249	90	department	department	PROPN
fnp-5842	249	91	of	of	ADP
fnp-5842	249	92	neurology	neurology	NOUN
fnp-5842	249	93	,	,	PUNCT
fnp-5842	249	94	ludwig	ludwig	PROPN
fnp-5842	249	95	maximilian	maximilian	PROPN
fnp-5842	249	96	university	university	PROPN
fnp-5842	249	97	,	,	PUNCT
fnp-5842	249	98	munich	munich	PROPN
fnp-5842	249	99	,	,	PUNCT
fnp-5842	249	100	germany	germany	PROPN
fnp-5842	249	101	background	background	NOUN
fnp-5842	249	102	:	:	PUNCT
fnp-5842	249	103	the	the	DET
fnp-5842	249	104	molecular	molecular	ADJ
fnp-5842	249	105	basis	basis	NOUN
fnp-5842	249	106	for	for	ADP
fnp-5842	249	107	accelerated	accelerated	ADJ
fnp-5842	249	108	cognitive	cognitive	ADJ
fnp-5842	249	109	decline	decline	NOUN
fnp-5842	249	110	seen	see	VERB
fnp-5842	249	111	in	in	ADP
fnp-5842	249	112	alzheimer	alzheimer	PROPN
fnp-5842	249	113	’s	’s	PART
fnp-5842	249	114	disease	disease	NOUN
fnp-5842	249	115	(	(	PUNCT
fnp-5842	249	116	ad	ad	NOUN
fnp-5842	249	117	)	)	PUNCT
fnp-5842	249	118	cases	case	NOUN
fnp-5842	249	119	presenting	present	VERB
fnp-5842	249	120	with	with	ADP
fnp-5842	249	121	cortical	cortical	ADJ
fnp-5842	249	122	alpha	alpha	NOUN
fnp-5842	249	123	-	-	PUNCT
fnp-5842	249	124	synuclein	synuclein	NOUN
fnp-5842	249	125	co	co	NOUN
fnp-5842	249	126	-	-	NOUN
fnp-5842	249	127	pathology	pathology	NOUN
fnp-5842	249	128	is	be	AUX
fnp-5842	249	129	not	not	PART
fnp-5842	249	130	well	well	ADV
fnp-5842	249	131	understood	understand	VERB
fnp-5842	249	132	.	.	PUNCT
fnp-5842	250	1	mouse	mouse	NOUN
fnp-5842	250	2	experiments	experiment	NOUN
fnp-5842	250	3	have	have	AUX
fnp-5842	250	4	shown	show	VERB
fnp-5842	250	5	adverse	adverse	ADJ
fnp-5842	250	6	interactions	interaction	NOUN
fnp-5842	250	7	between	between	ADP
fnp-5842	250	8	tau	tau	PROPN
fnp-5842	250	9	and	and	CCONJ
fnp-5842	250	10	alpha	alpha	NOUN
fnp-5842	250	11	-	-	PUNCT
fnp-5842	250	12	synuclein	synuclein	NOUN
fnp-5842	250	13	,	,	PUNCT
fnp-5842	250	14	but	but	CCONJ
fnp-5842	250	15	how	how	SCONJ
fnp-5842	250	16	this	this	DET
fnp-5842	250	17	finding	finding	NOUN
fnp-5842	250	18	translates	translate	VERB
fnp-5842	250	19	to	to	ADP
fnp-5842	250	20	humans	human	NOUN
fnp-5842	250	21	from	from	ADP
fnp-5842	250	22	a	a	DET
fnp-5842	250	23	genome	genome	NOUN
fnp-5842	250	24	-	-	PUNCT
fnp-5842	250	25	centered	center	VERB
fnp-5842	250	26	point	point	NOUN
fnp-5842	250	27	of	of	ADP
fnp-5842	250	28	view	view	NOUN
fnp-5842	250	29	remains	remain	VERB
fnp-5842	250	30	unknown	unknown	ADJ
fnp-5842	250	31	.	.	PUNCT
fnp-5842	251	1	materials	material	NOUN
fnp-5842	251	2	and	and	CCONJ
fnp-5842	251	3	methods	method	NOUN
fnp-5842	251	4	:	:	PUNCT
fnp-5842	251	5	whole	whole	ADJ
fnp-5842	251	6	genome	genome	NOUN
fnp-5842	251	7	sequencing	sequencing	NOUN
fnp-5842	251	8	was	be	AUX
fnp-5842	251	9	performed	perform	VERB
fnp-5842	251	10	on	on	ADP
fnp-5842	251	11	137	137	NUM
fnp-5842	251	12	neuropathologically	neuropathologically	ADV
fnp-5842	251	13	defined	define	VERB
fnp-5842	251	14	ad	ad	NOUN
fnp-5842	251	15	cases	case	NOUN
fnp-5842	251	16	,	,	PUNCT
fnp-5842	251	17	36	36	NUM
fnp-5842	251	18	of	of	ADP
fnp-5842	251	19	which	which	PRON
fnp-5842	251	20	presented	present	VERB
fnp-5842	251	21	with	with	ADP
fnp-5842	251	22	neocortical	neocortical	ADJ
fnp-5842	251	23	alpha	alpha	NOUN
fnp-5842	251	24	-	-	PUNCT
fnp-5842	251	25	synuclein	synuclein	NOUN
fnp-5842	251	26	co	co	NOUN
fnp-5842	251	27	-	-	NOUN
fnp-5842	251	28	pathology	pathology	NOUN
fnp-5842	251	29	(	(	PUNCT
fnp-5842	251	30	braak	braak	NOUN
fnp-5842	251	31	stage	stage	VERB
fnp-5842	251	32	6	6	NUM
fnp-5842	251	33	)	)	PUNCT
fnp-5842	251	34	.	.	PUNCT
fnp-5842	252	1	polygenic	polygenic	ADJ
fnp-5842	252	2	risk	risk	NOUN
fnp-5842	252	3	scores	score	NOUN
fnp-5842	252	4	were	be	AUX
fnp-5842	252	5	calculated	calculate	VERB
fnp-5842	252	6	.	.	PUNCT
fnp-5842	253	1	single	single	ADJ
fnp-5842	253	2	-	-	PUNCT
fnp-5842	253	3	nucleus	nucleus	NOUN
fnp-5842	253	4	rna	rna	NOUN
fnp-5842	253	5	sequencing	sequencing	NOUN
fnp-5842	253	6	and	and	CCONJ
fnp-5842	253	7	western	western	ADJ
fnp-5842	253	8	blot	blot	NOUN
fnp-5842	253	9	data	datum	NOUN
fnp-5842	253	10	were	be	AUX
fnp-5842	253	11	collected	collect	VERB
fnp-5842	253	12	from	from	ADP
fnp-5842	253	13	post	post	ADJ
fnp-5842	253	14	-	-	ADJ
fnp-5842	253	15	mortem	mortem	ADJ
fnp-5842	253	16	tissue	tissue	NOUN
fnp-5842	253	17	.	.	PUNCT
fnp-5842	254	1	bioinformatic	bioinformatic	ADJ
fnp-5842	254	2	analysis	analysis	NOUN
fnp-5842	254	3	of	of	ADP
fnp-5842	254	4	a	a	DET
fnp-5842	254	5	large	large	ADJ
fnp-5842	254	6	external	external	ADJ
fnp-5842	254	7	dataset	dataset	NOUN
fnp-5842	254	8	(	(	PUNCT
fnp-5842	254	9	n	n	CCONJ
fnp-5842	254	10	 	 	SPACE
fnp-5842	254	11	>	>	PUNCT
fnp-5842	254	12	 	 	SPACE
fnp-5842	254	13	300	300	NUM
fnp-5842	254	14	)	)	PUNCT
fnp-5842	254	15	served	serve	VERB
fnp-5842	254	16	as	as	ADP
fnp-5842	254	17	external	external	ADJ
fnp-5842	254	18	validation	validation	NOUN
fnp-5842	254	19	.	.	PUNCT
fnp-5842	255	1	transcriptomic	transcriptomic	ADJ
fnp-5842	255	2	and	and	CCONJ
fnp-5842	255	3	proteomic	proteomic	ADJ
fnp-5842	255	4	experiments	experiment	NOUN
fnp-5842	255	5	were	be	AUX
fnp-5842	255	6	carried	carry	VERB
fnp-5842	255	7	out	out	ADP
fnp-5842	255	8	in	in	ADP
fnp-5842	255	9	cell	cell	NOUN
fnp-5842	255	10	lines	line	NOUN
fnp-5842	255	11	and	and	CCONJ
fnp-5842	255	12	cortical	cortical	ADJ
fnp-5842	255	13	organoids	organoid	NOUN
fnp-5842	255	14	derived	derive	VERB
fnp-5842	255	15	from	from	ADP
fnp-5842	255	16	ipscs	ipsc	NOUN
fnp-5842	255	17	.	.	PUNCT
fnp-5842	256	1	results	result	NOUN
fnp-5842	256	2	:	:	PUNCT
fnp-5842	256	3	ad	ad	NOUN
fnp-5842	256	4	brains	brain	NOUN
fnp-5842	256	5	with	with	ADP
fnp-5842	256	6	alpha	alpha	NOUN
fnp-5842	256	7	-	-	PUNCT
fnp-5842	256	8	synuclein	synuclein	NOUN
fnp-5842	256	9	co	co	NOUN
fnp-5842	256	10	-	-	NOUN
fnp-5842	256	11	pathology	pathology	NOUN
fnp-5842	256	12	had	have	AUX
fnp-5842	256	13	significantly	significantly	ADV
fnp-5842	256	14	higher	high	ADJ
fnp-5842	256	15	polygenic	polygenic	ADJ
fnp-5842	256	16	risk	risk	NOUN
fnp-5842	256	17	scores	score	NOUN
fnp-5842	256	18	for	for	ADP
fnp-5842	256	19	parkinson	parkinson	NOUN
fnp-5842	256	20	’s	’s	PART
fnp-5842	256	21	disease	disease	NOUN
fnp-5842	256	22	,	,	PUNCT
fnp-5842	256	23	which	which	PRON
fnp-5842	256	24	could	could	AUX
fnp-5842	256	25	be	be	AUX
fnp-5842	256	26	partially	partially	ADV
fnp-5842	256	27	explained	explain	VERB
fnp-5842	256	28	by	by	ADP
fnp-5842	256	29	variants	variant	NOUN
fnp-5842	256	30	associated	associate	VERB
fnp-5842	256	31	with	with	ADP
fnp-5842	256	32	higher	high	ADJ
fnp-5842	256	33	expression	expression	NOUN
fnp-5842	256	34	of	of	ADP
fnp-5842	256	35	snca	snca	NOUN
fnp-5842	256	36	(	(	PUNCT
fnp-5842	256	37	the	the	DET
fnp-5842	256	38	gene	gene	NOUN
fnp-5842	256	39	symbol	symbol	NOUN
fnp-5842	256	40	for	for	ADP
fnp-5842	256	41	alpha	alpha	NOUN
fnp-5842	256	42	-	-	PUNCT
fnp-5842	256	43	synuclein	synuclein	NOUN
fnp-5842	256	44	)	)	PUNCT
fnp-5842	256	45	.	.	PUNCT
fnp-5842	257	1	single	single	ADJ
fnp-5842	257	2	-	-	PUNCT
fnp-5842	257	3	nucleus	nucleus	NOUN
fnp-5842	257	4	rna	rna	NOUN
fnp-5842	257	5	sequencing	sequencing	NOUN
fnp-5842	257	6	revealed	reveal	VERB
fnp-5842	257	7	a	a	DET
fnp-5842	257	8	higher	high	ADJ
fnp-5842	257	9	expression	expression	NOUN
fnp-5842	257	10	of	of	ADP
fnp-5842	257	11	mapt	mapt	NOUN
fnp-5842	257	12	,	,	PUNCT
fnp-5842	257	13	the	the	DET
fnp-5842	257	14	gene	gene	NOUN
fnp-5842	257	15	encoding	encode	VERB
fnp-5842	257	16	microtubule	microtubule	NOUN
fnp-5842	257	17	-	-	PUNCT
fnp-5842	257	18	associated	associate	VERB
fnp-5842	257	19	protein	protein	NOUN
fnp-5842	257	20	tau	tau	NOUN
fnp-5842	257	21	,	,	PUNCT
fnp-5842	257	22	in	in	ADP
fnp-5842	257	23	co	co	NOUN
fnp-5842	257	24	-	-	NOUN
fnp-5842	257	25	pathology	pathology	NOUN
fnp-5842	257	26	cases	case	NOUN
fnp-5842	257	27	.	.	PUNCT
fnp-5842	258	1	protein	protein	NOUN
fnp-5842	258	2	and	and	CCONJ
fnp-5842	258	3	mrna	mrna	PROPN
fnp-5842	258	4	expression	expression	NOUN
fnp-5842	258	5	of	of	ADP
fnp-5842	258	6	mapt	mapt	NOUN
fnp-5842	258	7	and	and	CCONJ
fnp-5842	258	8	snca	snca	NOUN
fnp-5842	258	9	were	be	AUX
fnp-5842	258	10	positively	positively	ADV
fnp-5842	258	11	correlated	correlate	VERB
fnp-5842	258	12	in	in	ADP
fnp-5842	258	13	an	an	DET
fnp-5842	258	14	external	external	ADJ
fnp-5842	258	15	cohort	cohort	NOUN
fnp-5842	258	16	.	.	PUNCT
fnp-5842	259	1	ultimately	ultimately	ADV
fnp-5842	259	2	,	,	PUNCT
fnp-5842	259	3	cell	cell	NOUN
fnp-5842	259	4	culture	culture	NOUN
fnp-5842	259	5	experiments	experiment	NOUN
fnp-5842	259	6	demonstrated	demonstrate	VERB
fnp-5842	259	7	that	that	SCONJ
fnp-5842	259	8	overexpression	overexpression	NOUN
fnp-5842	259	9	of	of	ADP
fnp-5842	259	10	snca	snca	NOUN
fnp-5842	259	11	was	be	AUX
fnp-5842	259	12	sufficient	sufficient	ADJ
fnp-5842	259	13	to	to	PART
fnp-5842	259	14	drive	drive	VERB
fnp-5842	259	15	accumulation	accumulation	NOUN
fnp-5842	259	16	of	of	ADP
fnp-5842	259	17	soluble	soluble	ADJ
fnp-5842	259	18	tau	tau	PROPN
fnp-5842	259	19	.	.	PUNCT
fnp-5842	260	1	conclusion	conclusion	NOUN
fnp-5842	260	2	:	:	PUNCT
fnp-5842	260	3	we	we	PRON
fnp-5842	260	4	show	show	VERB
fnp-5842	260	5	that	that	SCONJ
fnp-5842	260	6	alpha	alpha	NOUN
fnp-5842	260	7	-	-	PUNCT
fnp-5842	260	8	synuclein	synuclein	NOUN
fnp-5842	260	9	co	co	NOUN
fnp-5842	260	10	-	-	NOUN
fnp-5842	260	11	pathology	pathology	NOUN
fnp-5842	260	12	brains	brain	NOUN
fnp-5842	260	13	are	be	AUX
fnp-5842	260	14	characterized	characterize	VERB
fnp-5842	260	15	by	by	ADP
fnp-5842	260	16	higher	high	ADJ
fnp-5842	260	17	tau	tau	PROPN
fnp-5842	260	18	levels	level	NOUN
fnp-5842	260	19	and	and	CCONJ
fnp-5842	260	20	that	that	SCONJ
fnp-5842	260	21	increasing	increase	VERB
fnp-5842	260	22	alpha	alpha	NOUN
fnp-5842	260	23	-	-	PUNCT
fnp-5842	260	24	synuclein	synuclein	NOUN
fnp-5842	260	25	expression	expression	NOUN
fnp-5842	260	26	is	be	AUX
fnp-5842	260	27	sufficient	sufficient	ADJ
fnp-5842	260	28	to	to	PART
fnp-5842	260	29	drive	drive	VERB
fnp-5842	260	30	tau	tau	PROPN
fnp-5842	260	31	accumulation	accumulation	NOUN
fnp-5842	260	32	.	.	PUNCT
fnp-5842	261	1	our	our	PRON
fnp-5842	261	2	results	result	NOUN
fnp-5842	261	3	reveal	reveal	VERB
fnp-5842	261	4	that	that	SCONJ
fnp-5842	261	5	tau	tau	PROPN
fnp-5842	261	6	and	and	CCONJ
fnp-5842	261	7	alpha	alpha	NOUN
fnp-5842	261	8	-	-	PUNCT
fnp-5842	261	9	synuclein	synuclein	NOUN
fnp-5842	261	10	can	can	AUX
fnp-5842	261	11	synergistically	synergistically	ADV
fnp-5842	261	12	drive	drive	VERB
fnp-5842	261	13	dementia	dementia	NOUN
fnp-5842	261	14	-	-	PUNCT
fnp-5842	261	15	related	relate	VERB
fnp-5842	261	16	pathology	pathology	NOUN
fnp-5842	261	17	.	.	PUNCT
fnp-5842	262	1	p21	p21	PROPN
fnp-5842	262	2	free	free	ADJ
fnp-5842	262	3	neuropathol	neuropathol	NOUN
fnp-5842	262	4	5:19:33	5:19:33	NUM
fnp-5842	262	5	frontotemporal	frontotemporal	ADJ
fnp-5842	262	6	dementia	dementia	NOUN
fnp-5842	262	7	patient	patient	NOUN
fnp-5842	262	8	neurons	neuron	NOUN
fnp-5842	262	9	with	with	ADP
fnp-5842	262	10	the	the	DET
fnp-5842	262	11	mapt	mapt	NOUN
fnp-5842	262	12	-	-	PUNCT
fnp-5842	262	13	n279k	n279k	NOUN
fnp-5842	262	14	mutation	mutation	NOUN
fnp-5842	262	15	are	be	AUX
fnp-5842	262	16	responsive	responsive	ADJ
fnp-5842	262	17	to	to	ADP
fnp-5842	262	18	tau	tau	PROPN
fnp-5842	262	19	filaments	filament	NOUN
fnp-5842	262	20	and	and	CCONJ
fnp-5842	262	21	contribute	contribute	VERB
fnp-5842	262	22	to	to	ADP
fnp-5842	262	23	neuroinflammation	neuroinflammation	NOUN
fnp-5842	262	24	in	in	ADP
fnp-5842	262	25	vivo	vivo	PROPN
fnp-5842	262	26	julie	julie	PROPN
fnp-5842	262	27	j.	j.	PROPN
fnp-5842	262	28	mcinvale1	mcinvale1	PROPN
fnp-5842	262	29	,	,	PUNCT
fnp-5842	262	30	matti	matti	PROPN
fnp-5842	262	31	lam2	lam2	PROPN
fnp-5842	262	32	,	,	PUNCT
fnp-5842	262	33	river	river	NOUN
fnp-5842	262	34	kim1	kim1	PROPN
fnp-5842	262	35	,	,	PUNCT
fnp-5842	262	36	markus	markus	PROPN
fnp-5842	262	37	d.	d.	PROPN
fnp-5842	262	38	siegelin1	siegelin1	PROPN
fnp-5842	262	39	,	,	PUNCT
fnp-5842	262	40	james	james	PROPN
fnp-5842	262	41	e.	e.	PROPN
fnp-5842	262	42	goldman1,3	goldman1,3	PROPN
fnp-5842	262	43	,	,	PUNCT
fnp-5842	262	44	dennis	dennis	PROPN
fnp-5842	262	45	w.	w.	PROPN
fnp-5842	262	46	dickson4	dickson4	PROPN
fnp-5842	262	47	,	,	PUNCT
fnp-5842	262	48	vilas	vilas	PROPN
fnp-5842	262	49	menon2,3	menon2,3	PROPN
fnp-5842	262	50	,	,	PUNCT
fnp-5842	262	51	peter	peter	PROPN
fnp-5842	262	52	canoll1	canoll1	PROPN
fnp-5842	262	53	,	,	PUNCT
fnp-5842	262	54	gunnar	gunnar	VERB
fnp-5842	262	55	hargus1,3	hargus1,3	PROPN
fnp-5842	262	56	1	1	NUM
fnp-5842	262	57	department	department	NOUN
fnp-5842	262	58	of	of	ADP
fnp-5842	262	59	pathology	pathology	PROPN
fnp-5842	262	60	&	&	CCONJ
fnp-5842	262	61	cell	cell	NOUN
fnp-5842	262	62	biology	biology	NOUN
fnp-5842	262	63	,	,	PUNCT
fnp-5842	262	64	columbia	columbia	PROPN
fnp-5842	262	65	university	university	PROPN
fnp-5842	262	66	,	,	PUNCT
fnp-5842	262	67	new	new	PROPN
fnp-5842	262	68	york	york	PROPN
fnp-5842	262	69	,	,	PUNCT
fnp-5842	262	70	ny	ny	PROPN
fnp-5842	262	71	,	,	PUNCT
fnp-5842	262	72	10032	10032	NUM
fnp-5842	262	73	,	,	PUNCT
fnp-5842	262	74	usa	usa	PROPN
fnp-5842	262	75	2	2	NUM
fnp-5842	262	76	center	center	NOUN
fnp-5842	262	77	for	for	ADP
fnp-5842	262	78	translational	translational	ADJ
fnp-5842	262	79	&	&	CCONJ
fnp-5842	262	80	computational	computational	ADJ
fnp-5842	262	81	neuroimmunology	neuroimmunology	PROPN
fnp-5842	262	82	,	,	PUNCT
fnp-5842	262	83	department	department	NOUN
fnp-5842	262	84	of	of	ADP
fnp-5842	262	85	neurology	neurology	NOUN
fnp-5842	262	86	,	,	PUNCT
fnp-5842	262	87	columbia	columbia	PROPN
fnp-5842	262	88	university	university	PROPN
fnp-5842	262	89	irving	irving	PROPN
fnp-5842	262	90	medical	medical	ADJ
fnp-5842	262	91	center	center	NOUN
fnp-5842	262	92	,	,	PUNCT
fnp-5842	262	93	new	new	PROPN
fnp-5842	262	94	york	york	PROPN
fnp-5842	262	95	,	,	PUNCT
fnp-5842	262	96	ny	ny	PROPN
fnp-5842	262	97	,	,	PUNCT
fnp-5842	262	98	10032	10032	NUM
fnp-5842	262	99	,	,	PUNCT
fnp-5842	262	100	usa	usa	PROPN
fnp-5842	262	101	3	3	NUM
fnp-5842	262	102	taub	taub	PROPN
fnp-5842	262	103	institute	institute	PROPN
fnp-5842	262	104	for	for	ADP
fnp-5842	262	105	research	research	NOUN
fnp-5842	262	106	on	on	ADP
fnp-5842	262	107	alzheimer	alzheimer	PROPN
fnp-5842	262	108	's	's	PART
fnp-5842	262	109	disease	disease	NOUN
fnp-5842	262	110	&	&	CCONJ
fnp-5842	262	111	the	the	DET
fnp-5842	262	112	aging	age	VERB
fnp-5842	262	113	brain	brain	NOUN
fnp-5842	262	114	,	,	PUNCT
fnp-5842	262	115	columbia	columbia	PROPN
fnp-5842	262	116	university	university	PROPN
fnp-5842	262	117	,	,	PUNCT
fnp-5842	262	118	new	new	PROPN
fnp-5842	262	119	york	york	PROPN
fnp-5842	262	120	,	,	PUNCT
fnp-5842	262	121	ny	ny	PROPN
fnp-5842	262	122	,	,	PUNCT
fnp-5842	262	123	10032	10032	NUM
fnp-5842	262	124	,	,	PUNCT
fnp-5842	262	125	usa	usa	PROPN
fnp-5842	262	126	4	4	NUM
fnp-5842	262	127	department	department	NOUN
fnp-5842	262	128	of	of	ADP
fnp-5842	262	129	neuroscience	neuroscience	NOUN
fnp-5842	262	130	,	,	PUNCT
fnp-5842	262	131	the	the	DET
fnp-5842	262	132	mayo	mayo	PROPN
fnp-5842	262	133	clinic	clinic	PROPN
fnp-5842	262	134	florida	florida	PROPN
fnp-5842	262	135	,	,	PUNCT
fnp-5842	262	136	jacksonville	jacksonville	PROPN
fnp-5842	262	137	,	,	PUNCT
fnp-5842	262	138	fl	fl	PROPN
fnp-5842	262	139	,	,	PUNCT
fnp-5842	262	140	32224	32224	NUM
fnp-5842	262	141	,	,	PUNCT
fnp-5842	262	142	usa	usa	PROPN
fnp-5842	262	143	frontotemporal	frontotemporal	ADJ
fnp-5842	262	144	dementia	dementia	NOUN
fnp-5842	262	145	(	(	PUNCT
fnp-5842	262	146	ftd	ftd	NOUN
fnp-5842	262	147	)	)	PUNCT
fnp-5842	262	148	is	be	AUX
fnp-5842	262	149	a	a	DET
fnp-5842	262	150	heterogeneous	heterogeneous	ADJ
fnp-5842	262	151	group	group	NOUN
fnp-5842	262	152	of	of	ADP
fnp-5842	262	153	early	early	ADJ
fnp-5842	262	154	-	-	PUNCT
fnp-5842	262	155	onset	onset	NOUN
fnp-5842	262	156	dementias	dementia	NOUN
fnp-5842	262	157	leading	lead	VERB
fnp-5842	262	158	to	to	ADP
fnp-5842	262	159	impairment	impairment	NOUN
fnp-5842	262	160	of	of	ADP
fnp-5842	262	161	cognition	cognition	NOUN
fnp-5842	262	162	,	,	PUNCT
fnp-5842	262	163	language	language	NOUN
fnp-5842	262	164	and	and	CCONJ
fnp-5842	262	165	behavior	behavior	NOUN
fnp-5842	262	166	.	.	PUNCT
fnp-5842	263	1	ftd	ftd	PROPN
fnp-5842	263	2	can	can	AUX
fnp-5842	263	3	be	be	AUX
fnp-5842	263	4	caused	cause	VERB
fnp-5842	263	5	by	by	ADP
fnp-5842	263	6	deposition	deposition	NOUN
fnp-5842	263	7	of	of	ADP
fnp-5842	263	8	hyperphosphorylated	hyperphosphorylated	ADJ
fnp-5842	263	9	tau	tau	PROPN
fnp-5842	263	10	(	(	PUNCT
fnp-5842	263	11	p	p	PROPN
fnp-5842	263	12	-	-	PUNCT
fnp-5842	263	13	tau	tau	NOUN
fnp-5842	263	14	)	)	PUNCT
fnp-5842	263	15	in	in	ADP
fnp-5842	263	16	neurons	neuron	NOUN
fnp-5842	263	17	and	and	CCONJ
fnp-5842	263	18	glial	glial	ADJ
fnp-5842	263	19	cells	cell	NOUN
fnp-5842	263	20	in	in	ADP
fnp-5842	263	21	various	various	ADJ
fnp-5842	263	22	brain	brain	NOUN
fnp-5842	263	23	regions	region	NOUN
fnp-5842	263	24	throughout	throughout	ADP
fnp-5842	263	25	the	the	DET
fnp-5842	263	26	patient	patient	ADJ
fnp-5842	263	27	brains	brain	NOUN
fnp-5842	263	28	.	.	PUNCT
fnp-5842	264	1	however	however	ADV
fnp-5842	264	2	,	,	PUNCT
fnp-5842	264	3	the	the	DET
fnp-5842	264	4	mechanisms	mechanism	NOUN
fnp-5842	264	5	leading	lead	VERB
fnp-5842	264	6	to	to	ADP
fnp-5842	264	7	neurodegeneration	neurodegeneration	NOUN
fnp-5842	264	8	are	be	AUX
fnp-5842	264	9	still	still	ADV
fnp-5842	264	10	largely	largely	ADV
fnp-5842	264	11	unknown	unknown	ADJ
fnp-5842	264	12	and	and	CCONJ
fnp-5842	264	13	a	a	DET
fnp-5842	264	14	curative	curative	ADJ
fnp-5842	264	15	therapy	therapy	NOUN
fnp-5842	264	16	does	do	AUX
fnp-5842	264	17	not	not	PART
fnp-5842	264	18	exist	exist	VERB
fnp-5842	264	19	.	.	PUNCT
fnp-5842	265	1	here	here	ADV
fnp-5842	265	2	,	,	PUNCT
fnp-5842	265	3	we	we	PRON
fnp-5842	265	4	applied	apply	VERB
fnp-5842	265	5	a	a	DET
fnp-5842	265	6	stem	stem	NOUN
fnp-5842	265	7	cell	cell	NOUN
fnp-5842	265	8	-	-	PUNCT
fnp-5842	265	9	based	base	VERB
fnp-5842	265	10	approach	approach	NOUN
fnp-5842	265	11	combined	combine	VERB
fnp-5842	265	12	with	with	ADP
fnp-5842	265	13	single	single	ADJ
fnp-5842	265	14	-	-	PUNCT
fnp-5842	265	15	cell	cell	NOUN
fnp-5842	265	16	analyses	analysis	NOUN
fnp-5842	265	17	of	of	ADP
fnp-5842	265	18	ftd	ftd	NOUN
fnp-5842	265	19	patient	patient	ADJ
fnp-5842	265	20	brains	brain	NOUN
fnp-5842	265	21	and	and	CCONJ
fnp-5842	265	22	differentiated	differentiate	VERB
fnp-5842	265	23	ftd	ftd	NOUN
fnp-5842	265	24	patient	patient	NOUN
fnp-5842	265	25	-	-	PUNCT
fnp-5842	265	26	derived	derive	VERB
fnp-5842	265	27	induced	induce	VERB
fnp-5842	265	28	pluripotent	pluripotent	ADJ
fnp-5842	265	29	stem	stem	NOUN
fnp-5842	265	30	cells	cell	NOUN
fnp-5842	265	31	(	(	PUNCT
fnp-5842	265	32	ipscs	ipsc	NOUN
fnp-5842	265	33	)	)	PUNCT
fnp-5842	265	34	carrying	carry	VERB
fnp-5842	265	35	the	the	DET
fnp-5842	265	36	mapt	mapt	NOUN
fnp-5842	265	37	-	-	PUNCT
fnp-5842	265	38	n279k	n279k	NOUN
fnp-5842	265	39	mutation	mutation	NOUN
fnp-5842	265	40	and	and	CCONJ
fnp-5842	265	41	healthy	healthy	ADJ
fnp-5842	265	42	control	control	NOUN
fnp-5842	265	43	ipscs	ipsc	NOUN
fnp-5842	265	44	into	into	ADP
fnp-5842	265	45	neurons	neuron	NOUN
fnp-5842	265	46	.	.	PUNCT
fnp-5842	266	1	we	we	PRON
fnp-5842	266	2	found	find	VERB
fnp-5842	266	3	disease	disease	NOUN
fnp-5842	266	4	-	-	PUNCT
fnp-5842	266	5	relevant	relevant	ADJ
fnp-5842	266	6	changes	change	NOUN
fnp-5842	266	7	in	in	ADP
fnp-5842	266	8	ftd	ftd	NOUN
fnp-5842	266	9	neurons	neuron	NOUN
fnp-5842	266	10	associated	associate	VERB
fnp-5842	266	11	with	with	ADP
fnp-5842	266	12	mis	mi	NOUN
fnp-5842	266	13	-	-	NOUN
fnp-5842	266	14	splicing	splicing	NOUN
fnp-5842	266	15	of	of	ADP
fnp-5842	266	16	tau	tau	PROPN
fnp-5842	266	17	,	,	PUNCT
fnp-5842	266	18	p	p	PROPN
fnp-5842	266	19	-	-	PUNCT
fnp-5842	266	20	tau	tau	PROPN
fnp-5842	266	21	pathology	pathology	NOUN
fnp-5842	266	22	,	,	PUNCT
fnp-5842	266	23	neurite	neurite	ADJ
fnp-5842	266	24	outgrowth	outgrowth	NOUN
fnp-5842	266	25	deficits	deficit	NOUN
fnp-5842	266	26	,	,	PUNCT
fnp-5842	266	27	and	and	CCONJ
fnp-5842	266	28	increased	increase	VERB
fnp-5842	266	29	oxidative	oxidative	ADJ
fnp-5842	266	30	stress	stress	NOUN
fnp-5842	266	31	and	and	CCONJ
fnp-5842	266	32	neuroinflammation	neuroinflammation	NOUN
fnp-5842	266	33	with	with	ADP
fnp-5842	266	34	an	an	DET
fnp-5842	266	35	upregulation	upregulation	NOUN
fnp-5842	266	36	of	of	ADP
fnp-5842	266	37	pro	pro	ADJ
fnp-5842	266	38	-	-	ADJ
fnp-5842	266	39	inflammatory	inflammatory	ADJ
fnp-5842	266	40	genes	gene	NOUN
fnp-5842	266	41	,	,	PUNCT
fnp-5842	266	42	several	several	ADJ
fnp-5842	266	43	of	of	ADP
fnp-5842	266	44	which	which	PRON
fnp-5842	266	45	were	be	AUX
fnp-5842	266	46	also	also	ADV
fnp-5842	266	47	upregulated	upregulate	VERB
fnp-5842	266	48	in	in	ADP
fnp-5842	266	49	neurons	neuron	NOUN
fnp-5842	266	50	in	in	ADP
fnp-5842	266	51	ftd	ftd	PROPN
fnp-5842	266	52	patient	patient	NOUN
fnp-5842	266	53	brains	brain	NOUN
fnp-5842	266	54	carrying	carry	VERB
fnp-5842	266	55	the	the	DET
fnp-5842	266	56	same	same	ADJ
fnp-5842	266	57	mapt	mapt	NOUN
fnp-5842	266	58	-	-	PUNCT
fnp-5842	266	59	n279k	n279k	PROPN
fnp-5842	266	60	mutation	mutation	NOUN
fnp-5842	266	61	.	.	PUNCT
fnp-5842	267	1	tau	tau	PROPN
fnp-5842	267	2	filaments	filament	NOUN
fnp-5842	267	3	isolated	isolate	VERB
fnp-5842	267	4	from	from	ADP
fnp-5842	267	5	ftd	ftd	PROPN
fnp-5842	267	6	patient	patient	NOUN
fnp-5842	267	7	brains	brain	NOUN
fnp-5842	267	8	with	with	ADP
fnp-5842	267	9	mapt	mapt	NOUN
fnp-5842	267	10	-	-	PUNCT
fnp-5842	267	11	n279k	n279k	NOUN
fnp-5842	267	12	further	far	ADV
fnp-5842	267	13	upregulated	upregulate	VERB
fnp-5842	267	14	expression	expression	NOUN
fnp-5842	267	15	of	of	ADP
fnp-5842	267	16	the	the	DET
fnp-5842	267	17	pro	pro	ADJ
fnp-5842	267	18	-	-	ADJ
fnp-5842	267	19	inflammatory	inflammatory	ADJ
fnp-5842	267	20	marker	marker	NOUN
fnp-5842	267	21	osteopontin	osteopontin	NOUN
fnp-5842	267	22	in	in	ADP
fnp-5842	267	23	ftd	ftd	PROPN
fnp-5842	267	24	neurons	neuron	NOUN
fnp-5842	267	25	and	and	CCONJ
fnp-5842	267	26	altered	alter	VERB
fnp-5842	267	27	pathways	pathway	NOUN
fnp-5842	267	28	related	relate	VERB
fnp-5842	267	29	to	to	ADP
fnp-5842	267	30	the	the	DET
fnp-5842	267	31	unfolded	unfolded	ADJ
fnp-5842	267	32	protein	protein	NOUN
fnp-5842	267	33	response	response	NOUN
fnp-5842	267	34	and	and	CCONJ
fnp-5842	267	35	proteasomal	proteasomal	ADJ
fnp-5842	267	36	function	function	NOUN
fnp-5842	267	37	.	.	PUNCT
fnp-5842	268	1	when	when	SCONJ
fnp-5842	268	2	injected	inject	VERB
fnp-5842	268	3	into	into	ADP
fnp-5842	268	4	the	the	DET
fnp-5842	268	5	mouse	mouse	NOUN
fnp-5842	268	6	brains	brain	NOUN
fnp-5842	268	7	,	,	PUNCT
fnp-5842	268	8	ftd	ftd	PROPN
fnp-5842	268	9	neurons	neuron	NOUN
fnp-5842	268	10	showed	show	VERB
fnp-5842	268	11	decreased	decrease	VERB
fnp-5842	268	12	survival	survival	NOUN
fnp-5842	268	13	and	and	CCONJ
fnp-5842	268	14	induced	induce	VERB
fnp-5842	268	15	an	an	DET
fnp-5842	268	16	increased	increase	VERB
fnp-5842	268	17	microglial	microglial	ADJ
fnp-5842	268	18	response	response	NOUN
fnp-5842	268	19	.	.	PUNCT
fnp-5842	269	1	decreased	decrease	VERB
fnp-5842	269	2	survival	survival	NOUN
fnp-5842	269	3	of	of	ADP
fnp-5842	269	4	ftd	ftd	PROPN
fnp-5842	269	5	neurons	neuron	NOUN
fnp-5842	269	6	was	be	AUX
fnp-5842	269	7	also	also	ADV
fnp-5842	269	8	noted	note	VERB
fnp-5842	269	9	when	when	SCONJ
fnp-5842	269	10	cells	cell	NOUN
fnp-5842	269	11	were	be	AUX
fnp-5842	269	12	co	co	VERB
fnp-5842	269	13	-	-	VERB
fnp-5842	269	14	injected	inject	VERB
fnp-5842	269	15	with	with	ADP
fnp-5842	269	16	ftd	ftd	PROPN
fnp-5842	269	17	tau	tau	PROPN
fnp-5842	269	18	filaments	filament	VERB
fnp-5842	269	19	into	into	ADP
fnp-5842	269	20	mouse	mouse	NOUN
fnp-5842	269	21	brains	brain	NOUN
fnp-5842	269	22	.	.	PUNCT
fnp-5842	270	1	interestingly	interestingly	ADV
fnp-5842	270	2	,	,	PUNCT
fnp-5842	270	3	alterations	alteration	NOUN
fnp-5842	270	4	of	of	ADP
fnp-5842	270	5	inflammatory	inflammatory	ADJ
fnp-5842	270	6	gene	gene	NOUN
fnp-5842	270	7	expression	expression	NOUN
fnp-5842	270	8	in	in	ADP
fnp-5842	270	9	engrafted	engraft	VERB
fnp-5842	270	10	neurons	neuron	NOUN
fnp-5842	270	11	resulted	result	VERB
fnp-5842	270	12	in	in	ADP
fnp-5842	270	13	altered	altered	ADJ
fnp-5842	270	14	engraftment	engraftment	NOUN
fnp-5842	270	15	and	and	CCONJ
fnp-5842	270	16	microglial	microglial	ADJ
fnp-5842	270	17	infiltration	infiltration	NOUN
fnp-5842	270	18	.	.	PUNCT
fnp-5842	271	1	these	these	DET
fnp-5842	271	2	findings	finding	NOUN
fnp-5842	271	3	point	point	VERB
fnp-5842	271	4	towards	towards	ADP
fnp-5842	271	5	an	an	DET
fnp-5842	271	6	immune	immune	ADJ
fnp-5842	271	7	-	-	PUNCT
fnp-5842	271	8	modulatory	modulatory	NOUN
fnp-5842	271	9	role	role	NOUN
fnp-5842	271	10	of	of	ADP
fnp-5842	271	11	neurons	neuron	NOUN
fnp-5842	271	12	in	in	ADP
fnp-5842	271	13	ftd	ftd	PROPN
fnp-5842	271	14	and	and	CCONJ
fnp-5842	271	15	indicate	indicate	VERB
fnp-5842	271	16	that	that	SCONJ
fnp-5842	271	17	its	its	PRON
fnp-5842	271	18	alteration	alteration	NOUN
fnp-5842	271	19	may	may	AUX
fnp-5842	271	20	represent	represent	VERB
fnp-5842	271	21	a	a	DET
fnp-5842	271	22	potential	potential	ADJ
fnp-5842	271	23	therapeutic	therapeutic	ADJ
fnp-5842	271	24	target	target	NOUN
fnp-5842	271	25	in	in	ADP
fnp-5842	271	26	ftd	ftd	PROPN
fnp-5842	271	27	.	.	PUNCT
fnp-5842	272	1	p22	p22	VERB
fnp-5842	272	2	free	free	ADJ
fnp-5842	272	3	neuropathol	neuropathol	NOUN
fnp-5842	272	4	5:19:34	5:19:34	NUM
fnp-5842	272	5	alterations	alteration	NOUN
fnp-5842	272	6	of	of	ADP
fnp-5842	272	7	er	er	INTJ
fnp-5842	272	8	-	-	PUNCT
fnp-5842	272	9	co	co	ADJ
fnp-5842	272	10	-	-	ADJ
fnp-5842	272	11	chaperone	chaperone	ADJ
fnp-5842	272	12	sil1	sil1	NOUN
fnp-5842	272	13	in	in	ADP
fnp-5842	272	14	amyotrophic	amyotrophic	ADJ
fnp-5842	272	15	lateral	lateral	ADJ
fnp-5842	272	16	sclerosis	sclerosis	NOUN
fnp-5842	272	17	(	(	PUNCT
fnp-5842	272	18	als	als	NOUN
fnp-5842	272	19	)	)	PUNCT
fnp-5842	272	20	haihong	haihong	PROPN
fnp-5842	272	21	guo1	guo1	PROPN
fnp-5842	272	22	,	,	PUNCT
fnp-5842	272	23	alfred	alfred	PROPN
fnp-5842	272	24	yamoah1,2,3	yamoah1,2,3	PROPN
fnp-5842	272	25	,	,	PUNCT
fnp-5842	272	26	priyanka	priyanka	PROPN
fnp-5842	272	27	tripathi1,2,3	tripathi1,2,3	PROPN
fnp-5842	272	28	,	,	PUNCT
fnp-5842	272	29	antonio	antonio	PROPN
fnp-5842	272	30	sechi4	sechi4	PROPN
fnp-5842	272	31	,	,	PUNCT
fnp-5842	272	32	istvan	istvan	PROPN
fnp-5842	272	33	katona1,5	katona1,5	PROPN
fnp-5842	272	34	,	,	PUNCT
fnp-5842	272	35	eleonora	eleonora	PROPN
fnp-5842	272	36	aronica6	aronica6	PROPN
fnp-5842	272	37	,	,	PUNCT
fnp-5842	272	38	marcel	marcel	PROPN
fnp-5842	272	39	naumann7	naumann7	PROPN
fnp-5842	272	40	,	,	PUNCT
fnp-5842	272	41	andreas	andreas	PROPN
fnp-5842	272	42	hermann7,8	hermann7,8	PROPN
fnp-5842	272	43	,	,	PUNCT
fnp-5842	272	44	harry	harry	PROPN
fnp-5842	272	45	steinbusch2,3	steinbusch2,3	PROPN
fnp-5842	272	46	,	,	PUNCT
fnp-5842	272	47	andreas	andreas	PROPN
fnp-5842	272	48	roos9,10	roos9,10	PROPN
fnp-5842	272	49	,	,	PUNCT
fnp-5842	272	50	joachim	joachim	PROPN
fnp-5842	272	51	weis1	weis1	PROPN
fnp-5842	272	52	,	,	PUNCT
fnp-5842	272	53	*	*	PROPN
fnp-5842	272	54	,	,	PUNCT
fnp-5842	272	55	anand	anand	PROPN
fnp-5842	272	56	goswami1	goswami1	PROPN
fnp-5842	272	57	,	,	PUNCT
fnp-5842	272	58	11	11	NUM
fnp-5842	272	59	,	,	PUNCT
fnp-5842	272	60	12	12	NUM
fnp-5842	272	61	,	,	PUNCT
fnp-5842	272	62	*	*	PROPN
fnp-5842	272	63	1	1	NUM
fnp-5842	272	64	institute	institute	NOUN
fnp-5842	272	65	of	of	ADP
fnp-5842	272	66	neuropathology	neuropathology	NOUN
fnp-5842	272	67	,	,	PUNCT
fnp-5842	272	68	rwth	rwth	PROPN
fnp-5842	272	69	aachen	aachen	PROPN
fnp-5842	272	70	university	university	PROPN
fnp-5842	272	71	hospital	hospital	NOUN
fnp-5842	272	72	,	,	PUNCT
fnp-5842	272	73	52074	52074	NUM
fnp-5842	272	74	aachen	aachen	PROPN
fnp-5842	272	75	,	,	PUNCT
fnp-5842	272	76	germany	germany	PROPN
fnp-5842	272	77	2	2	NUM
fnp-5842	272	78	department	department	NOUN
fnp-5842	272	79	of	of	ADP
fnp-5842	272	80	psychiatry	psychiatry	NOUN
fnp-5842	272	81	and	and	CCONJ
fnp-5842	272	82	neuropsychology	neuropsychology	NOUN
fnp-5842	272	83	,	,	PUNCT
fnp-5842	272	84	school	school	NOUN
fnp-5842	272	85	for	for	ADP
fnp-5842	272	86	mental	mental	ADJ
fnp-5842	272	87	health	health	NOUN
fnp-5842	272	88	and	and	CCONJ
fnp-5842	272	89	neuroscience	neuroscience	NOUN
fnp-5842	272	90	,	,	PUNCT
fnp-5842	272	91	maastricht	maastricht	PROPN
fnp-5842	272	92	university	university	PROPN
fnp-5842	272	93	,	,	PUNCT
fnp-5842	272	94	6229	6229	NUM
fnp-5842	272	95	er	er	INTJ
fnp-5842	272	96	maastricht	maastricht	PROPN
fnp-5842	272	97	,	,	PUNCT
fnp-5842	272	98	the	the	DET
fnp-5842	272	99	netherlands	netherlands	PROPN
fnp-5842	272	100	3	3	NUM
fnp-5842	272	101	euron	euron	PROPN
fnp-5842	272	102	european	european	PROPN
fnp-5842	272	103	graduate	graduate	PROPN
fnp-5842	272	104	school	school	NOUN
fnp-5842	272	105	of	of	ADP
fnp-5842	272	106	neuroscience	neuroscience	NOUN
fnp-5842	272	107	,	,	PUNCT
fnp-5842	272	108	maastricht	maastricht	PROPN
fnp-5842	272	109	university	university	PROPN
fnp-5842	272	110	,	,	PUNCT
fnp-5842	272	111	6229	6229	NUM
fnp-5842	272	112	er	er	INTJ
fnp-5842	272	113	maastricht	maastricht	PROPN
fnp-5842	272	114	,	,	PUNCT
fnp-5842	272	115	the	the	DET
fnp-5842	272	116	netherlands	netherlands	PROPN
fnp-5842	272	117	4	4	NUM
fnp-5842	272	118	institute	institute	PROPN
fnp-5842	272	119	of	of	ADP
fnp-5842	272	120	cell	cell	NOUN
fnp-5842	272	121	and	and	CCONJ
fnp-5842	272	122	tumorbiology	tumorbiology	NOUN
fnp-5842	272	123	,	,	PUNCT
fnp-5842	272	124	rwth	rwth	PROPN
fnp-5842	272	125	aachen	aachen	PROPN
fnp-5842	272	126	university	university	PROPN
fnp-5842	272	127	hospital	hospital	NOUN
fnp-5842	272	128	,	,	PUNCT
fnp-5842	272	129	52074	52074	NUM
fnp-5842	272	130	aachen	aachen	PROPN
fnp-5842	272	131	,	,	PUNCT
fnp-5842	272	132	germany	germany	PROPN
fnp-5842	272	133	5	5	NUM
fnp-5842	272	134	department	department	PROPN
fnp-5842	272	135	of	of	ADP
fnp-5842	272	136	neurology	neurology	NOUN
fnp-5842	272	137	,	,	PUNCT
fnp-5842	272	138	houston	houston	PROPN
fnp-5842	272	139	methodist	methodist	PROPN
fnp-5842	272	140	research	research	PROPN
fnp-5842	272	141	institute	institute	PROPN
fnp-5842	272	142	,	,	PUNCT
fnp-5842	272	143	tx	tx	PROPN
fnp-5842	272	144	77030	77030	NUM
fnp-5842	272	145	houston	houston	PROPN
fnp-5842	272	146	,	,	PUNCT
fnp-5842	272	147	united	united	PROPN
fnp-5842	272	148	states	states	PROPN
fnp-5842	272	149	6	6	NUM
fnp-5842	272	150	division	division	NOUN
fnp-5842	272	151	of	of	ADP
fnp-5842	272	152	neuropathology	neuropathology	NOUN
fnp-5842	272	153	,	,	PUNCT
fnp-5842	272	154	department	department	NOUN
fnp-5842	272	155	of	of	ADP
fnp-5842	272	156	pathology	pathology	PROPN
fnp-5842	272	157	,	,	PUNCT
fnp-5842	272	158	academic	academic	ADJ
fnp-5842	272	159	medical	medical	ADJ
fnp-5842	272	160	centre	centre	NOUN
fnp-5842	272	161	,	,	PUNCT
fnp-5842	272	162	1105	1105	NUM
fnp-5842	272	163	az	az	PROPN
fnp-5842	272	164	,	,	PUNCT
fnp-5842	272	165	amsterdam	amsterdam	PROPN
fnp-5842	272	166	,	,	PUNCT
fnp-5842	272	167	the	the	DET
fnp-5842	272	168	netherlands	netherlands	PROPN
fnp-5842	272	169	7	7	NUM
fnp-5842	272	170	translational	translational	ADJ
fnp-5842	272	171	neurodegeneration	neurodegeneration	NOUN
fnp-5842	272	172	section	section	NOUN
fnp-5842	272	173	“	"	PUNCT
fnp-5842	272	174	albrecht	albrecht	PROPN
fnp-5842	272	175	-	-	PUNCT
fnp-5842	272	176	kossel	kossel	NOUN
fnp-5842	272	177	’’	’'	PUNCT
fnp-5842	272	178	,	,	PUNCT
fnp-5842	272	179	department	department	NOUN
fnp-5842	272	180	of	of	ADP
fnp-5842	272	181	neurology	neurology	NOUN
fnp-5842	272	182	and	and	CCONJ
fnp-5842	272	183	centre	centre	NOUN
fnp-5842	272	184	for	for	ADP
fnp-5842	272	185	transdisciplinary	transdisciplinary	ADJ
fnp-5842	272	186	neurosciences	neuroscience	NOUN
fnp-5842	272	187	rostock	rostock	NOUN
fnp-5842	272	188	(	(	PUNCT
fnp-5842	272	189	ctnr	ctnr	PROPN
fnp-5842	272	190	)	)	PUNCT
fnp-5842	272	191	,	,	PUNCT
fnp-5842	272	192	university	university	NOUN
fnp-5842	272	193	medical	medical	ADJ
fnp-5842	272	194	centre	centre	PROPN
fnp-5842	272	195	rostock	rostock	PROPN
fnp-5842	272	196	,	,	PUNCT
fnp-5842	272	197	18147	18147	NUM
fnp-5842	272	198	rostock	rostock	PROPN
fnp-5842	272	199	,	,	PUNCT
fnp-5842	272	200	germany	germany	PROPN
fnp-5842	272	201	8	8	NUM
fnp-5842	272	202	german	german	ADJ
fnp-5842	272	203	centre	centre	NOUN
fnp-5842	272	204	for	for	ADP
fnp-5842	272	205	neurodegenerative	neurodegenerative	ADJ
fnp-5842	272	206	diseases	disease	NOUN
fnp-5842	272	207	(	(	PUNCT
fnp-5842	272	208	dzne	dzne	NOUN
fnp-5842	272	209	)	)	PUNCT
fnp-5842	272	210	rostock	rostock	PROPN
fnp-5842	272	211	/	/	SYM
fnp-5842	272	212	greifswald	greifswald	PROPN
fnp-5842	272	213	,	,	PUNCT
fnp-5842	272	214	18147	18147	NUM
fnp-5842	272	215	rostock	rostock	PROPN
fnp-5842	272	216	,	,	PUNCT
fnp-5842	272	217	germany	germany	PROPN
fnp-5842	272	218	9	9	NUM
fnp-5842	272	219	department	department	PROPN
fnp-5842	272	220	of	of	ADP
fnp-5842	272	221	neurology	neurology	NOUN
fnp-5842	272	222	,	,	PUNCT
fnp-5842	272	223	heimer	heimer	PROPN
fnp-5842	272	224	institute	institute	PROPN
fnp-5842	272	225	for	for	ADP
fnp-5842	272	226	muscle	muscle	NOUN
fnp-5842	272	227	research	research	NOUN
fnp-5842	272	228	,	,	PUNCT
fnp-5842	272	229	university	university	NOUN
fnp-5842	272	230	hospital	hospital	NOUN
fnp-5842	272	231	bergmannsheil	bergmannsheil	NOUN
fnp-5842	272	232	,	,	PUNCT
fnp-5842	272	233	ruhr	ruhr	PROPN
fnp-5842	272	234	university	university	PROPN
fnp-5842	272	235	bochum	bochum	NOUN
fnp-5842	272	236	,	,	PUNCT
fnp-5842	272	237	44789	44789	NUM
fnp-5842	272	238	bochum	bochum	NOUN
fnp-5842	272	239	,	,	PUNCT
fnp-5842	272	240	germany	germany	PROPN
fnp-5842	272	241	10	10	NUM
fnp-5842	272	242	department	department	PROPN
fnp-5842	272	243	of	of	ADP
fnp-5842	272	244	neuropediatrics	neuropediatric	NOUN
fnp-5842	272	245	and	and	CCONJ
fnp-5842	272	246	neuromuscular	neuromuscular	ADJ
fnp-5842	272	247	centre	centre	NOUN
fnp-5842	272	248	for	for	ADP
fnp-5842	272	249	children	child	NOUN
fnp-5842	272	250	and	and	CCONJ
fnp-5842	272	251	adolescents	adolescent	NOUN
fnp-5842	272	252	,	,	PUNCT
fnp-5842	272	253	centre	centre	NOUN
fnp-5842	272	254	for	for	ADP
fnp-5842	272	255	translational	translational	ADJ
fnp-5842	272	256	neuroand	neuroand	ADJ
fnp-5842	272	257	behavioural	behavioural	ADJ
fnp-5842	272	258	sciences	sciences	PROPN
fnp-5842	272	259	,	,	PUNCT
fnp-5842	272	260	university	university	NOUN
fnp-5842	272	261	duisburg	duisburg	PROPN
fnp-5842	272	262	-	-	PUNCT
fnp-5842	272	263	essen	essen	NOUN
fnp-5842	272	264	,	,	PUNCT
fnp-5842	272	265	45147	45147	NUM
fnp-5842	272	266	essen	essen	PROPN
fnp-5842	272	267	,	,	PUNCT
fnp-5842	272	268	germany	germany	PROPN
fnp-5842	272	269	11	11	NUM
fnp-5842	272	270	department	department	PROPN
fnp-5842	272	271	of	of	ADP
fnp-5842	272	272	neurology	neurology	NOUN
fnp-5842	272	273	,	,	PUNCT
fnp-5842	272	274	centre	centre	NOUN
fnp-5842	272	275	for	for	ADP
fnp-5842	272	276	motor	motor	NOUN
fnp-5842	272	277	neuron	neuron	PROPN
fnp-5842	272	278	biology	biology	NOUN
fnp-5842	272	279	and	and	CCONJ
fnp-5842	272	280	disease	disease	PROPN
fnp-5842	272	281	,	,	PUNCT
fnp-5842	272	282	columbia	columbia	PROPN
fnp-5842	272	283	university	university	PROPN
fnp-5842	272	284	,	,	PUNCT
fnp-5842	272	285	10032	10032	NUM
fnp-5842	272	286	new	new	PROPN
fnp-5842	272	287	york	york	PROPN
fnp-5842	272	288	,	,	PUNCT
fnp-5842	272	289	united	united	PROPN
fnp-5842	272	290	states	states	PROPN
fnp-5842	272	291	12	12	NUM
fnp-5842	272	292	department	department	NOUN
fnp-5842	272	293	of	of	ADP
fnp-5842	272	294	neurology	neurology	NOUN
fnp-5842	272	295	,	,	PUNCT
fnp-5842	272	296	eleanor	eleanor	NOUN
fnp-5842	272	297	and	and	CCONJ
fnp-5842	272	298	lou	lou	PROPN
fnp-5842	272	299	gehrig	gehrig	PROPN
fnp-5842	272	300	als	als	PROPN
fnp-5842	272	301	centre	centre	PROPN
fnp-5842	272	302	,	,	PUNCT
fnp-5842	272	303	columbia	columbia	PROPN
fnp-5842	272	304	university	university	PROPN
fnp-5842	272	305	,	,	PUNCT
fnp-5842	272	306	10032	10032	NUM
fnp-5842	272	307	new	new	PROPN
fnp-5842	272	308	york	york	PROPN
fnp-5842	272	309	,	,	PUNCT
fnp-5842	272	310	united	united	PROPN
fnp-5842	272	311	states	states	PROPN
fnp-5842	272	312	*	*	PUNCT
fnp-5842	272	313	equal	equal	ADJ
fnp-5842	272	314	contribution	contribution	NOUN
fnp-5842	272	315	amyotrophic	amyotrophic	ADJ
fnp-5842	272	316	lateral	lateral	ADJ
fnp-5842	272	317	sclerosis	sclerosis	NOUN
fnp-5842	272	318	(	(	PUNCT
fnp-5842	272	319	als	als	NOUN
fnp-5842	272	320	)	)	PUNCT
fnp-5842	272	321	is	be	AUX
fnp-5842	272	322	a	a	DET
fnp-5842	272	323	devastating	devastating	ADJ
fnp-5842	272	324	disease	disease	NOUN
fnp-5842	272	325	characterized	characterize	VERB
fnp-5842	272	326	by	by	ADP
fnp-5842	272	327	progressive	progressive	ADJ
fnp-5842	272	328	loss	loss	NOUN
fnp-5842	272	329	of	of	ADP
fnp-5842	272	330	upper	upper	ADJ
fnp-5842	272	331	and	and	CCONJ
fnp-5842	272	332	lower	low	ADJ
fnp-5842	272	333	motor	motor	NOUN
fnp-5842	272	334	neurons	neuron	NOUN
fnp-5842	272	335	(	(	PUNCT
fnp-5842	272	336	mns	mns	PROPN
fnp-5842	272	337	)	)	PUNCT
fnp-5842	272	338	.	.	PUNCT
fnp-5842	273	1	recent	recent	ADJ
fnp-5842	273	2	studies	study	NOUN
fnp-5842	273	3	showed	show	VERB
fnp-5842	273	4	that	that	SCONJ
fnp-5842	273	5	selectively	selectively	ADV
fnp-5842	273	6	viable	viable	ADJ
fnp-5842	273	7	neurons	neuron	NOUN
fnp-5842	273	8	are	be	AUX
fnp-5842	273	9	often	often	ADV
fnp-5842	273	10	equipped	equip	VERB
fnp-5842	273	11	with	with	ADP
fnp-5842	273	12	protective	protective	ADJ
fnp-5842	273	13	factors	factor	NOUN
fnp-5842	273	14	,	,	PUNCT
fnp-5842	273	15	while	while	SCONJ
fnp-5842	273	16	vulnerable	vulnerable	ADJ
fnp-5842	273	17	neurons	neuron	NOUN
fnp-5842	273	18	lack	lack	VERB
fnp-5842	273	19	them	they	PRON
fnp-5842	273	20	.	.	PUNCT
fnp-5842	274	1	among	among	ADP
fnp-5842	274	2	others	other	NOUN
fnp-5842	274	3	,	,	PUNCT
fnp-5842	274	4	the	the	DET
fnp-5842	274	5	er	er	INTJ
fnp-5842	274	6	co	co	NOUN
fnp-5842	274	7	-	-	ADJ
fnp-5842	274	8	chaperone	chaperone	ADJ
fnp-5842	274	9	sil1	sil1	NOUN
fnp-5842	274	10	,	,	PUNCT
fnp-5842	274	11	mutated	mutate	VERB
fnp-5842	274	12	in	in	ADP
fnp-5842	274	13	marinesco	marinesco	ADJ
fnp-5842	274	14	-	-	PUNCT
fnp-5842	274	15	sjögren	sjögren	NOUN
fnp-5842	274	16	syndrome	syndrome	NOUN
fnp-5842	274	17	(	(	PUNCT
fnp-5842	274	18	mss	mss	PROPN
fnp-5842	274	19	)	)	PUNCT
fnp-5842	274	20	,	,	PUNCT
fnp-5842	274	21	supports	support	VERB
fnp-5842	274	22	such	such	ADJ
fnp-5842	274	23	selective	selective	ADJ
fnp-5842	274	24	mn	mn	PROPN
fnp-5842	274	25	viability	viability	NOUN
fnp-5842	274	26	not	not	PART
fnp-5842	274	27	only	only	ADV
fnp-5842	274	28	in	in	ADP
fnp-5842	274	29	mss	mss	PROPN
fnp-5842	274	30	pathology	pathology	NOUN
fnp-5842	274	31	but	but	CCONJ
fnp-5842	274	32	also	also	ADV
fnp-5842	274	33	in	in	ADP
fnp-5842	274	34	als	als	NOUN
fnp-5842	274	35	pathology	pathology	NOUN
fnp-5842	274	36	.	.	PUNCT
fnp-5842	275	1	however	however	ADV
fnp-5842	275	2	,	,	PUNCT
fnp-5842	275	3	the	the	DET
fnp-5842	275	4	precise	precise	ADJ
fnp-5842	275	5	molecular	molecular	ADJ
fnp-5842	275	6	mechanism(s	mechanism(s	NOUN
fnp-5842	275	7	)	)	PUNCT
fnp-5842	275	8	of	of	ADP
fnp-5842	275	9	such	such	ADJ
fnp-5842	275	10	neuroprotection	neuroprotection	NOUN
fnp-5842	275	11	as	as	ADV
fnp-5842	275	12	well	well	ADV
fnp-5842	275	13	as	as	ADP
fnp-5842	275	14	its	its	PRON
fnp-5842	275	15	role	role	NOUN
fnp-5842	275	16	in	in	ADP
fnp-5842	275	17	maintaining	maintain	VERB
fnp-5842	275	18	neuronal	neuronal	ADJ
fnp-5842	275	19	proteostasis	proteostasis	NOUN
fnp-5842	275	20	is	be	AUX
fnp-5842	275	21	largely	largely	ADV
fnp-5842	275	22	unclear	unclear	ADJ
fnp-5842	275	23	.	.	PUNCT
fnp-5842	276	1	we	we	PRON
fnp-5842	276	2	aimed	aim	VERB
fnp-5842	276	3	to	to	PART
fnp-5842	276	4	validate	validate	VERB
fnp-5842	276	5	the	the	DET
fnp-5842	276	6	correlation	correlation	NOUN
fnp-5842	276	7	between	between	ADP
fnp-5842	276	8	sil1	sil1	NOUN
fnp-5842	276	9	and	and	CCONJ
fnp-5842	276	10	als	al	NOUN
fnp-5842	276	11	-	-	PUNCT
fnp-5842	276	12	associated	associate	VERB
fnp-5842	276	13	protein	protein	NOUN
fnp-5842	276	14	aggregates	aggregate	NOUN
fnp-5842	276	15	in	in	ADP
fnp-5842	276	16	human	human	ADJ
fnp-5842	276	17	als	als	NOUN
fnp-5842	276	18	together	together	ADV
fnp-5842	276	19	with	with	ADP
fnp-5842	276	20	investigating	investigate	VERB
fnp-5842	276	21	the	the	DET
fnp-5842	276	22	neuroprotective	neuroprotective	ADJ
fnp-5842	276	23	role	role	NOUN
fnp-5842	276	24	of	of	ADP
fnp-5842	276	25	sil1	sil1	NOUN
fnp-5842	276	26	associated	associate	VERB
fnp-5842	276	27	with	with	ADP
fnp-5842	276	28	the	the	DET
fnp-5842	276	29	protein	protein	NOUN
fnp-5842	276	30	quality	quality	NOUN
fnp-5842	276	31	control	control	NOUN
fnp-5842	276	32	(	(	PUNCT
fnp-5842	276	33	pqc	pqc	NOUN
fnp-5842	276	34	)	)	PUNCT
fnp-5842	276	35	mechanism	mechanism	NOUN
fnp-5842	276	36	.	.	PUNCT
fnp-5842	277	1	we	we	PRON
fnp-5842	277	2	used	use	VERB
fnp-5842	277	3	als	als	NOUN
fnp-5842	277	4	postmortem	postmortem	NOUN
fnp-5842	277	5	autopsy	autopsy	ADJ
fnp-5842	277	6	materials	material	NOUN
fnp-5842	277	7	and	and	CCONJ
fnp-5842	277	8	compared	compare	VERB
fnp-5842	277	9	them	they	PRON
fnp-5842	277	10	with	with	ADP
fnp-5842	277	11	als	als	NOUN
fnp-5842	277	12	cell	cell	NOUN
fnp-5842	277	13	models	model	NOUN
fnp-5842	277	14	expressing	express	VERB
fnp-5842	277	15	als	als	NOUN
fnp-5842	277	16	-	-	PUNCT
fnp-5842	277	17	causing	cause	VERB
fnp-5842	277	18	mutant	mutant	ADJ
fnp-5842	277	19	proteins	protein	NOUN
fnp-5842	277	20	.	.	PUNCT
fnp-5842	278	1	our	our	PRON
fnp-5842	278	2	results	result	NOUN
fnp-5842	278	3	confirmed	confirm	VERB
fnp-5842	278	4	that	that	SCONJ
fnp-5842	278	5	in	in	ADP
fnp-5842	278	6	the	the	DET
fnp-5842	278	7	als	als	NOUN
fnp-5842	278	8	mns	mn	NOUN
fnp-5842	278	9	,	,	PUNCT
fnp-5842	278	10	sil1	sil1	NOUN
fnp-5842	278	11	protein	protein	NOUN
fnp-5842	278	12	levels	level	NOUN
fnp-5842	278	13	were	be	AUX
fnp-5842	278	14	specifically	specifically	ADV
fnp-5842	278	15	elevated	elevate	VERB
fnp-5842	278	16	in	in	ADP
fnp-5842	278	17	slow	slow	ADJ
fnp-5842	278	18	fatigue	fatigue	NOUN
fnp-5842	278	19	-	-	PUNCT
fnp-5842	278	20	resistant	resistant	ADJ
fnp-5842	278	21	mns	mns	PROPN
fnp-5842	278	22	(	(	PUNCT
fnp-5842	278	23	smns	smn	NOUN
fnp-5842	278	24	)	)	PUNCT
fnp-5842	278	25	,	,	PUNCT
fnp-5842	278	26	and	and	CCONJ
fnp-5842	278	27	reduced	reduced	ADJ
fnp-5842	278	28	sil1	sil1	NOUN
fnp-5842	278	29	levels	level	NOUN
fnp-5842	278	30	were	be	AUX
fnp-5842	278	31	linked	link	VERB
fnp-5842	278	32	to	to	ADP
fnp-5842	278	33	als	al	NOUN
fnp-5842	278	34	-	-	PUNCT
fnp-5842	278	35	associated	associate	VERB
fnp-5842	278	36	protein	protein	NOUN
fnp-5842	278	37	aggregates	aggregate	NOUN
fnp-5842	278	38	.	.	PUNCT
fnp-5842	279	1	besides	besides	SCONJ
fnp-5842	279	2	,	,	PUNCT
fnp-5842	279	3	sil1	sil1	NOUN
fnp-5842	279	4	was	be	AUX
fnp-5842	279	5	found	find	VERB
fnp-5842	279	6	to	to	PART
fnp-5842	279	7	be	be	AUX
fnp-5842	279	8	sequestered	sequester	VERB
fnp-5842	279	9	with	with	ADP
fnp-5842	279	10	various	various	ADJ
fnp-5842	279	11	forms	form	NOUN
fnp-5842	279	12	of	of	ADP
fnp-5842	279	13	ptdp-43	ptdp-43	PROPN
fnp-5842	279	14	and	and	CCONJ
fnp-5842	279	15	other	other	ADJ
fnp-5842	279	16	aggregates	aggregate	NOUN
fnp-5842	279	17	in	in	ADP
fnp-5842	279	18	als	als	NOUN
fnp-5842	279	19	spinal	spinal	ADJ
fnp-5842	279	20	mns	mns	PROPN
fnp-5842	279	21	as	as	ADV
fnp-5842	279	22	well	well	ADV
fnp-5842	279	23	as	as	ADP
fnp-5842	279	24	als	als	NOUN
fnp-5842	279	25	cell	cell	NOUN
fnp-5842	279	26	culture	culture	NOUN
fnp-5842	279	27	models	model	NOUN
fnp-5842	279	28	.	.	PUNCT
fnp-5842	280	1	overexpression	overexpression	NOUN
fnp-5842	280	2	of	of	ADP
fnp-5842	280	3	sil1	sil1	NOUN
fnp-5842	280	4	facilitated	facilitate	VERB
fnp-5842	280	5	the	the	DET
fnp-5842	280	6	clearance	clearance	NOUN
fnp-5842	280	7	of	of	ADP
fnp-5842	280	8	the	the	DET
fnp-5842	280	9	above	above	ADV
fnp-5842	280	10	-	-	PUNCT
fnp-5842	280	11	mentioned	mention	VERB
fnp-5842	280	12	pathogenic	pathogenic	ADJ
fnp-5842	280	13	aggregates	aggregate	NOUN
fnp-5842	280	14	in	in	ADP
fnp-5842	280	15	these	these	DET
fnp-5842	280	16	models	model	NOUN
fnp-5842	280	17	.	.	PUNCT
fnp-5842	281	1	furthermore	furthermore	ADV
fnp-5842	281	2	,	,	PUNCT
fnp-5842	281	3	sil1	sil1	NOUN
fnp-5842	281	4	could	could	AUX
fnp-5842	281	5	activate	activate	VERB
fnp-5842	281	6	autophagy	autophagy	ADJ
fnp-5842	281	7	pathways	pathway	NOUN
fnp-5842	281	8	by	by	ADP
fnp-5842	281	9	promoting	promote	VERB
fnp-5842	281	10	fusion	fusion	NOUN
fnp-5842	281	11	of	of	ADP
fnp-5842	281	12	autophagosomes	autophagosome	NOUN
fnp-5842	281	13	with	with	ADP
fnp-5842	281	14	lysosomes	lysosome	NOUN
fnp-5842	281	15	.	.	PUNCT
fnp-5842	282	1	in	in	ADP
fnp-5842	282	2	summary	summary	NOUN
fnp-5842	282	3	,	,	PUNCT
fnp-5842	282	4	our	our	PRON
fnp-5842	282	5	results	result	NOUN
fnp-5842	282	6	suggest	suggest	VERB
fnp-5842	282	7	that	that	SCONJ
fnp-5842	282	8	sil1	sil1	NOUN
fnp-5842	282	9	is	be	AUX
fnp-5842	282	10	promoting	promote	VERB
fnp-5842	282	11	neuronal	neuronal	ADJ
fnp-5842	282	12	pqc	pqc	NOUN
fnp-5842	282	13	and	and	CCONJ
fnp-5842	282	14	survival	survival	NOUN
fnp-5842	282	15	.	.	PUNCT
fnp-5842	283	1	conversely	conversely	ADV
fnp-5842	283	2	,	,	PUNCT
fnp-5842	283	3	disturbed	disturbed	ADJ
fnp-5842	283	4	sil1	sil1	NOUN
fnp-5842	283	5	function	function	NOUN
fnp-5842	283	6	could	could	AUX
fnp-5842	283	7	be	be	AUX
fnp-5842	283	8	detrimental	detrimental	ADJ
fnp-5842	283	9	to	to	ADP
fnp-5842	283	10	neurons	neuron	NOUN
fnp-5842	283	11	.	.	PUNCT
fnp-5842	284	1	p23	p23	NOUN
fnp-5842	284	2	free	free	ADJ
fnp-5842	284	3	neuropathol	neuropathol	NOUN
fnp-5842	285	1	5:19:36	5:19:36	NUM
fnp-5842	285	2	characterizing	characterize	VERB
fnp-5842	285	3	granular	granular	ADJ
fnp-5842	285	4	tau	tau	NOUN
fnp-5842	285	5	aggregates	aggregate	NOUN
fnp-5842	285	6	in	in	ADP
fnp-5842	285	7	astrocytes	astrocyte	NOUN
fnp-5842	285	8	in	in	ADP
fnp-5842	285	9	multiple	multiple	ADJ
fnp-5842	285	10	system	system	NOUN
fnp-5842	285	11	atrophy	atrophy	NOUN
fnp-5842	285	12	viktoria	viktoria	PROPN
fnp-5842	285	13	c.	c.	PROPN
fnp-5842	285	14	ruf1	ruf1	PROPN
fnp-5842	285	15	,	,	PUNCT
fnp-5842	285	16	doris	doris	PROPN
fnp-5842	285	17	weissenbrunner1,2	weissenbrunner1,2	PROPN
fnp-5842	285	18	,	,	PUNCT
fnp-5842	285	19	paul	paul	PROPN
fnp-5842	285	20	feyen1,2	feyen1,2	PROPN
fnp-5842	285	21	,	,	PUNCT
fnp-5842	285	22	jochen	jochen	PROPN
fnp-5842	285	23	herms1,2,3	herms1,2,3	PROPN
fnp-5842	285	24	1	1	NUM
fnp-5842	285	25	center	center	NOUN
fnp-5842	285	26	for	for	ADP
fnp-5842	285	27	neuropathology	neuropathology	NOUN
fnp-5842	285	28	and	and	CCONJ
fnp-5842	285	29	prion	prion	NOUN
fnp-5842	285	30	research	research	NOUN
fnp-5842	285	31	,	,	PUNCT
fnp-5842	285	32	faculty	faculty	NOUN
fnp-5842	285	33	of	of	ADP
fnp-5842	285	34	medicine	medicine	NOUN
fnp-5842	285	35	,	,	PUNCT
fnp-5842	285	36	lmu	lmu	PROPN
fnp-5842	285	37	munich	munich	PROPN
fnp-5842	285	38	,	,	PUNCT
fnp-5842	285	39	munich	munich	PROPN
fnp-5842	285	40	,	,	PUNCT
fnp-5842	285	41	germany	germany	PROPN
fnp-5842	285	42	2	2	NUM
fnp-5842	285	43	german	german	ADJ
fnp-5842	285	44	center	center	NOUN
fnp-5842	285	45	for	for	ADP
fnp-5842	285	46	neurodegenerative	neurodegenerative	ADJ
fnp-5842	285	47	diseases	disease	NOUN
fnp-5842	285	48	(	(	PUNCT
fnp-5842	285	49	dzne	dzne	NOUN
fnp-5842	285	50	)	)	PUNCT
fnp-5842	286	1	e.	e.	PROPN
fnp-5842	286	2	v.	v.	PROPN
fnp-5842	286	3	,	,	PUNCT
fnp-5842	286	4	site	site	NOUN
fnp-5842	286	5	munich	munich	PROPN
fnp-5842	286	6	,	,	PUNCT
fnp-5842	286	7	munich	munich	PROPN
fnp-5842	286	8	,	,	PUNCT
fnp-5842	286	9	germany	germany	PROPN
fnp-5842	286	10	3	3	NUM
fnp-5842	286	11	ludwig	ludwig	PROPN
fnp-5842	286	12	-	-	PUNCT
fnp-5842	286	13	maximilians	maximilians	PROPN
fnp-5842	286	14	-	-	PUNCT
fnp-5842	286	15	university	university	NOUN
fnp-5842	286	16	,	,	PUNCT
fnp-5842	286	17	munich	munich	PROPN
fnp-5842	286	18	cluster	cluster	NOUN
fnp-5842	286	19	of	of	ADP
fnp-5842	286	20	systems	system	NOUN
fnp-5842	286	21	neurology	neurology	NOUN
fnp-5842	286	22	(	(	PUNCT
fnp-5842	286	23	synergy	synergy	NOUN
fnp-5842	286	24	)	)	PUNCT
fnp-5842	286	25	,	,	PUNCT
fnp-5842	286	26	munich	munich	PROPN
fnp-5842	286	27	,	,	PUNCT
fnp-5842	286	28	germany	germany	PROPN
fnp-5842	286	29	introduction	introduction	NOUN
fnp-5842	286	30	:	:	PUNCT
fnp-5842	286	31	multiple	multiple	ADJ
fnp-5842	286	32	system	system	NOUN
fnp-5842	286	33	atrophy	atrophy	NOUN
fnp-5842	286	34	(	(	PUNCT
fnp-5842	286	35	msa	msa	PROPN
fnp-5842	286	36	)	)	PUNCT
fnp-5842	286	37	is	be	AUX
fnp-5842	286	38	a	a	DET
fnp-5842	286	39	rare	rare	ADJ
fnp-5842	286	40	adult	adult	NOUN
fnp-5842	286	41	-	-	PUNCT
fnp-5842	286	42	onset	onset	VERB
fnp-5842	286	43	fatal	fatal	ADJ
fnp-5842	286	44	neurodegenerative	neurodegenerative	ADJ
fnp-5842	286	45	disorder	disorder	NOUN
fnp-5842	286	46	characterized	characterize	VERB
fnp-5842	286	47	by	by	ADP
fnp-5842	286	48	alpha	alpha	NOUN
fnp-5842	286	49	-	-	PUNCT
fnp-5842	286	50	synuclein	synuclein	NOUN
fnp-5842	286	51	aggregation	aggregation	NOUN
fnp-5842	286	52	in	in	ADP
fnp-5842	286	53	oligodendrocytes	oligodendrocyte	NOUN
fnp-5842	286	54	.	.	PUNCT
fnp-5842	287	1	moreover	moreover	ADV
fnp-5842	287	2	,	,	PUNCT
fnp-5842	287	3	small	small	ADJ
fnp-5842	287	4	granular	granular	ADJ
fnp-5842	287	5	tau	tau	NOUN
fnp-5842	287	6	inclusions	inclusion	NOUN
fnp-5842	287	7	in	in	ADP
fnp-5842	287	8	the	the	DET
fnp-5842	287	9	white	white	ADJ
fnp-5842	287	10	matter	matter	NOUN
fnp-5842	287	11	were	be	AUX
fnp-5842	287	12	occasionally	occasionally	ADV
fnp-5842	287	13	,	,	PUNCT
fnp-5842	287	14	but	but	CCONJ
fnp-5842	287	15	not	not	PART
fnp-5842	287	16	extensively	extensively	ADV
fnp-5842	287	17	described	describe	VERB
fnp-5842	287	18	in	in	ADP
fnp-5842	287	19	the	the	DET
fnp-5842	287	20	literature	literature	NOUN
fnp-5842	287	21	and	and	CCONJ
fnp-5842	287	22	have	have	AUX
fnp-5842	287	23	been	be	AUX
fnp-5842	287	24	controversially	controversially	ADV
fnp-5842	287	25	discussed	discuss	VERB
fnp-5842	287	26	.	.	PUNCT
fnp-5842	288	1	based	base	VERB
fnp-5842	288	2	on	on	ADP
fnp-5842	288	3	the	the	DET
fnp-5842	288	4	finding	finding	NOUN
fnp-5842	288	5	from	from	ADP
fnp-5842	288	6	our	our	PRON
fnp-5842	288	7	snrna	snrna	ADJ
fnp-5842	288	8	-	-	PUNCT
fnp-5842	288	9	seq	seq	NOUN
fnp-5842	288	10	dataset	dataset	NOUN
fnp-5842	288	11	that	that	SCONJ
fnp-5842	288	12	mapt	mapt	NOUN
fnp-5842	288	13	is	be	AUX
fnp-5842	288	14	significantly	significantly	ADV
fnp-5842	288	15	upregulated	upregulate	VERB
fnp-5842	288	16	in	in	ADP
fnp-5842	288	17	astrocytes	astrocyte	NOUN
fnp-5842	288	18	in	in	ADP
fnp-5842	288	19	the	the	DET
fnp-5842	288	20	frontal	frontal	ADJ
fnp-5842	288	21	white	white	ADJ
fnp-5842	288	22	matter	matter	NOUN
fnp-5842	288	23	of	of	ADP
fnp-5842	288	24	msa	msa	PROPN
fnp-5842	288	25	patients	patient	NOUN
fnp-5842	288	26	,	,	PUNCT
fnp-5842	288	27	we	we	PRON
fnp-5842	288	28	sought	seek	VERB
fnp-5842	288	29	to	to	PART
fnp-5842	288	30	better	well	ADV
fnp-5842	288	31	and	and	CCONJ
fnp-5842	288	32	more	more	ADV
fnp-5842	288	33	comprehensively	comprehensively	ADV
fnp-5842	288	34	characterize	characterize	VERB
fnp-5842	288	35	the	the	DET
fnp-5842	288	36	observation	observation	NOUN
fnp-5842	288	37	of	of	ADP
fnp-5842	288	38	granular	granular	ADJ
fnp-5842	288	39	tau	tau	NOUN
fnp-5842	288	40	inclusions	inclusion	NOUN
fnp-5842	288	41	in	in	ADP
fnp-5842	288	42	msa	msa	PROPN
fnp-5842	288	43	.	.	PUNCT
fnp-5842	288	44	materials	material	NOUN
fnp-5842	288	45	and	and	CCONJ
fnp-5842	288	46	methods	method	NOUN
fnp-5842	288	47	:	:	PUNCT
fnp-5842	288	48	immunohistochemistry	immunohistochemistry	NOUN
fnp-5842	288	49	and	and	CCONJ
fnp-5842	288	50	immunofluorescence	immunofluorescence	NOUN
fnp-5842	288	51	as	as	ADV
fnp-5842	288	52	well	well	ADV
fnp-5842	288	53	as	as	ADP
fnp-5842	288	54	rnascope	rnascope	NOUN
fnp-5842	288	55	were	be	AUX
fnp-5842	288	56	applied	apply	VERB
fnp-5842	288	57	.	.	PUNCT
fnp-5842	289	1	results	result	NOUN
fnp-5842	289	2	:	:	PUNCT
fnp-5842	289	3	at8	at8	NOUN
fnp-5842	289	4	-	-	ADJ
fnp-5842	289	5	positive	positive	ADJ
fnp-5842	289	6	granules	granule	NOUN
fnp-5842	289	7	were	be	AUX
fnp-5842	289	8	a	a	DET
fnp-5842	289	9	common	common	ADJ
fnp-5842	289	10	finding	finding	NOUN
fnp-5842	289	11	although	although	SCONJ
fnp-5842	289	12	to	to	ADP
fnp-5842	289	13	a	a	DET
fnp-5842	289	14	highly	highly	ADV
fnp-5842	289	15	variable	variable	ADJ
fnp-5842	289	16	extent	extent	NOUN
fnp-5842	289	17	in	in	ADP
fnp-5842	289	18	the	the	DET
fnp-5842	289	19	white	white	ADJ
fnp-5842	289	20	matter	matter	NOUN
fnp-5842	289	21	of	of	ADP
fnp-5842	289	22	msa	msa	PROPN
fnp-5842	289	23	patients	patient	NOUN
fnp-5842	289	24	,	,	PUNCT
fnp-5842	289	25	whereas	whereas	SCONJ
fnp-5842	289	26	no	no	DET
fnp-5842	289	27	such	such	ADJ
fnp-5842	289	28	staining	stain	VERB
fnp-5842	289	29	was	be	AUX
fnp-5842	289	30	observed	observe	VERB
fnp-5842	289	31	in	in	ADP
fnp-5842	289	32	a	a	DET
fnp-5842	289	33	series	series	NOUN
fnp-5842	289	34	of	of	ADP
fnp-5842	289	35	non	non	ADJ
fnp-5842	289	36	-	-	ADJ
fnp-5842	289	37	neurodegenerative	neurodegenerative	ADJ
fnp-5842	289	38	controls	control	NOUN
fnp-5842	289	39	or	or	CCONJ
fnp-5842	289	40	patients	patient	NOUN
fnp-5842	289	41	with	with	ADP
fnp-5842	289	42	lbd	lbd	PROPN
fnp-5842	289	43	.	.	PUNCT
fnp-5842	290	1	the	the	DET
fnp-5842	290	2	granules	granule	NOUN
fnp-5842	290	3	partially	partially	ADV
fnp-5842	290	4	colocalized	colocalize	VERB
fnp-5842	290	5	with	with	ADP
fnp-5842	290	6	ptau	ptau	ADV
fnp-5842	290	7	-	-	PUNCT
fnp-5842	290	8	thr231	thr231	PROPN
fnp-5842	290	9	and	and	CCONJ
fnp-5842	290	10	ptau	ptau	ADV
fnp-5842	290	11	-	-	PUNCT
fnp-5842	290	12	ser396	ser396	NOUN
fnp-5842	290	13	as	as	ADV
fnp-5842	290	14	well	well	ADV
fnp-5842	290	15	as	as	ADP
fnp-5842	290	16	with	with	ADP
fnp-5842	290	17	rd3	rd3	PROPN
fnp-5842	290	18	or	or	CCONJ
fnp-5842	290	19	rd4	rd4	PROPN
fnp-5842	290	20	.	.	PUNCT
fnp-5842	291	1	co	co	VERB
fnp-5842	291	2	-	-	VERB
fnp-5842	291	3	staining	staining	ADJ
fnp-5842	291	4	of	of	ADP
fnp-5842	291	5	at8	at8	PROPN
fnp-5842	291	6	with	with	ADP
fnp-5842	291	7	gfap	gfap	PROPN
fnp-5842	291	8	revealed	reveal	VERB
fnp-5842	291	9	an	an	DET
fnp-5842	291	10	association	association	NOUN
fnp-5842	291	11	with	with	ADP
fnp-5842	291	12	astrocytes	astrocyte	NOUN
fnp-5842	291	13	without	without	ADP
fnp-5842	291	14	any	any	DET
fnp-5842	291	15	obvious	obvious	ADJ
fnp-5842	291	16	association	association	NOUN
fnp-5842	291	17	with	with	ADP
fnp-5842	291	18	oligodendrocytes	oligodendrocyte	NOUN
fnp-5842	291	19	or	or	CCONJ
fnp-5842	291	20	microglia	microglia	NOUN
fnp-5842	291	21	.	.	PUNCT
fnp-5842	292	1	while	while	SCONJ
fnp-5842	292	2	there	there	PRON
fnp-5842	292	3	was	be	VERB
fnp-5842	292	4	no	no	DET
fnp-5842	292	5	noticeable	noticeable	ADJ
fnp-5842	292	6	colocalization	colocalization	NOUN
fnp-5842	292	7	of	of	ADP
fnp-5842	292	8	ptau	ptau	PROPN
fnp-5842	292	9	and	and	CCONJ
fnp-5842	292	10	alpha	alpha	NOUN
fnp-5842	292	11	-	-	PUNCT
fnp-5842	292	12	synuclein	synuclein	NOUN
fnp-5842	292	13	inclusions	inclusion	NOUN
fnp-5842	292	14	,	,	PUNCT
fnp-5842	292	15	we	we	PRON
fnp-5842	292	16	find	find	VERB
fnp-5842	292	17	a	a	DET
fnp-5842	292	18	positive	positive	ADJ
fnp-5842	292	19	relationship	relationship	NOUN
fnp-5842	292	20	between	between	ADP
fnp-5842	292	21	the	the	DET
fnp-5842	292	22	load	load	NOUN
fnp-5842	292	23	of	of	ADP
fnp-5842	292	24	alpha	alpha	NOUN
fnp-5842	292	25	-	-	PUNCT
fnp-5842	292	26	synuclein	synuclein	NOUN
fnp-5842	292	27	pathology	pathology	NOUN
fnp-5842	292	28	and	and	CCONJ
fnp-5842	292	29	granular	granular	ADJ
fnp-5842	292	30	tau	tau	NOUN
fnp-5842	292	31	inclusions	inclusion	NOUN
fnp-5842	292	32	.	.	PUNCT
fnp-5842	293	1	conclusion	conclusion	NOUN
fnp-5842	293	2	:	:	PUNCT
fnp-5842	293	3	granular	granular	ADJ
fnp-5842	293	4	tau	tau	PROPN
fnp-5842	293	5	accumulations	accumulation	NOUN
fnp-5842	293	6	are	be	AUX
fnp-5842	293	7	a	a	DET
fnp-5842	293	8	common	common	ADJ
fnp-5842	293	9	feature	feature	NOUN
fnp-5842	293	10	in	in	ADP
fnp-5842	293	11	msa	msa	PROPN
fnp-5842	293	12	.	.	PUNCT
fnp-5842	294	1	the	the	DET
fnp-5842	294	2	inclusions	inclusion	NOUN
fnp-5842	294	3	,	,	PUNCT
fnp-5842	294	4	however	however	ADV
fnp-5842	294	5	,	,	PUNCT
fnp-5842	294	6	seem	seem	VERB
fnp-5842	294	7	to	to	PART
fnp-5842	294	8	be	be	AUX
fnp-5842	294	9	different	different	ADJ
fnp-5842	294	10	from	from	ADP
fnp-5842	294	11	other	other	ADJ
fnp-5842	294	12	known	know	VERB
fnp-5842	294	13	tau	tau	PROPN
fnp-5842	294	14	aggregates	aggregate	NOUN
fnp-5842	294	15	.	.	PUNCT
fnp-5842	295	1	while	while	SCONJ
fnp-5842	295	2	it	it	PRON
fnp-5842	295	3	is	be	AUX
fnp-5842	295	4	generally	generally	ADV
fnp-5842	295	5	assumed	assume	VERB
fnp-5842	295	6	that	that	SCONJ
fnp-5842	295	7	glial	glial	ADJ
fnp-5842	295	8	cells	cell	NOUN
fnp-5842	295	9	take	take	VERB
fnp-5842	295	10	up	up	ADP
fnp-5842	295	11	misfolded	misfolde	VERB
fnp-5842	295	12	tau	tau	PROPN
fnp-5842	295	13	from	from	ADP
fnp-5842	295	14	neurons	neuron	NOUN
fnp-5842	295	15	,	,	PUNCT
fnp-5842	295	16	the	the	DET
fnp-5842	295	17	upregulation	upregulation	NOUN
fnp-5842	295	18	of	of	ADP
fnp-5842	295	19	mapt	mapt	NOUN
fnp-5842	295	20	in	in	ADP
fnp-5842	295	21	astrocytes	astrocyte	NOUN
fnp-5842	295	22	may	may	AUX
fnp-5842	295	23	indicate	indicate	VERB
fnp-5842	295	24	that	that	SCONJ
fnp-5842	295	25	in	in	ADP
fnp-5842	295	26	this	this	DET
fnp-5842	295	27	case	case	NOUN
fnp-5842	295	28	tau	tau	NOUN
fnp-5842	295	29	accumulation	accumulation	NOUN
fnp-5842	295	30	may	may	AUX
fnp-5842	295	31	be	be	AUX
fnp-5842	295	32	a	a	DET
fnp-5842	295	33	consequence	consequence	NOUN
fnp-5842	295	34	of	of	ADP
fnp-5842	295	35	an	an	DET
fnp-5842	295	36	increased	increase	VERB
fnp-5842	295	37	expression	expression	NOUN
fnp-5842	295	38	of	of	ADP
fnp-5842	295	39	endogenous	endogenous	ADJ
fnp-5842	295	40	tau	tau	NOUN
fnp-5842	295	41	.	.	PUNCT
fnp-5842	296	1	v.	v.	ADP
fnp-5842	296	2	methods	method	NOUN
fnp-5842	296	3	and	and	CCONJ
fnp-5842	296	4	free	free	ADJ
fnp-5842	296	5	topics	topic	NOUN
fnp-5842	297	1	p24	p24	VERB
fnp-5842	297	2	free	free	ADJ
fnp-5842	297	3	neuropathol	neuropathol	NOUN
fnp-5842	297	4	5:19:37	5:19:37	NUM
fnp-5842	297	5	ultra	ultra	ADJ
fnp-5842	297	6	-	-	ADJ
fnp-5842	297	7	rapid	rapid	ADJ
fnp-5842	297	8	bacterial	bacterial	ADJ
fnp-5842	297	9	detection	detection	NOUN
fnp-5842	297	10	from	from	ADP
fnp-5842	297	11	neuropathology	neuropathology	NOUN
fnp-5842	297	12	specimens	specimen	NOUN
fnp-5842	297	13	using	use	VERB
fnp-5842	297	14	next	next	ADJ
fnp-5842	297	15	-	-	PUNCT
fnp-5842	297	16	generation	generation	NOUN
fnp-5842	297	17	pcr	pcr	NOUN
fnp-5842	297	18	and	and	CCONJ
fnp-5842	297	19	nanopore	nanopore	ADV
fnp-5842	297	20	sequencing	sequence	VERB
fnp-5842	297	21	daan	daan	PROPN
fnp-5842	297	22	brackel1	brackel1	PROPN
fnp-5842	297	23	,	,	PUNCT
fnp-5842	297	24	sander	sander	NOUN
fnp-5842	297	25	boden1	boden1	PROPN
fnp-5842	297	26	,	,	PUNCT
fnp-5842	297	27	anne	anne	PROPN
fnp-5842	297	28	albers2	albers2	PROPN
fnp-5842	297	29	,	,	PUNCT
fnp-5842	297	30	robin	robin	PROPN
fnp-5842	297	31	struijk3	struijk3	PROPN
fnp-5842	297	32	,	,	PUNCT
fnp-5842	297	33	christian	christian	PROPN
fnp-5842	297	34	thomas2	thomas2	PROPN
fnp-5842	297	35	,	,	PUNCT
fnp-5842	297	36	eefje	eefje	NOUN
fnp-5842	297	37	schrauwen1	schrauwen1	NOUN
fnp-5842	297	38	1	1	NUM
fnp-5842	297	39	centre	centre	NOUN
fnp-5842	297	40	of	of	ADP
fnp-5842	297	41	expertise	expertise	NOUN
fnp-5842	297	42	perspectives	perspective	NOUN
fnp-5842	297	43	in	in	ADP
fnp-5842	297	44	health	health	NOUN
fnp-5842	297	45	,	,	PUNCT
fnp-5842	297	46	research	research	NOUN
fnp-5842	297	47	group	group	NOUN
fnp-5842	297	48	analytical	analytical	ADJ
fnp-5842	297	49	techniques	technique	NOUN
fnp-5842	297	50	in	in	ADP
fnp-5842	297	51	the	the	DET
fnp-5842	297	52	life	life	NOUN
fnp-5842	297	53	sciences	science	NOUN
fnp-5842	297	54	,	,	PUNCT
fnp-5842	297	55	avans	avan	NOUN
fnp-5842	297	56	university	university	PROPN
fnp-5842	297	57	of	of	ADP
fnp-5842	297	58	applied	apply	VERB
fnp-5842	297	59	sciences	science	NOUN
fnp-5842	297	60	,	,	PUNCT
fnp-5842	297	61	breda	breda	PROPN
fnp-5842	297	62	,	,	PUNCT
fnp-5842	297	63	netherlands	netherlands	PROPN
fnp-5842	297	64	2	2	NUM
fnp-5842	297	65	institute	institute	PROPN
fnp-5842	297	66	of	of	ADP
fnp-5842	297	67	neuropathology	neuropathology	NOUN
fnp-5842	297	68	,	,	PUNCT
fnp-5842	297	69	university	university	NOUN
fnp-5842	297	70	hospital	hospital	NOUN
fnp-5842	297	71	münster	münster	NOUN
fnp-5842	297	72	,	,	PUNCT
fnp-5842	297	73	münster	münster	PROPN
fnp-5842	297	74	,	,	PUNCT
fnp-5842	297	75	germany	germany	PROPN
fnp-5842	297	76	3	3	NUM
fnp-5842	297	77	department	department	PROPN
fnp-5842	297	78	of	of	ADP
fnp-5842	297	79	research	research	PROPN
fnp-5842	297	80	&	&	CCONJ
fnp-5842	297	81	development	development	NOUN
fnp-5842	297	82	,	,	PUNCT
fnp-5842	297	83	molecular	molecular	ADJ
fnp-5842	297	84	biology	biology	NOUN
fnp-5842	297	85	systems	system	NOUN
fnp-5842	297	86	b.v	b.v	PROPN
fnp-5842	297	87	.	.	PROPN
fnp-5842	297	88	,	,	PUNCT
fnp-5842	297	89	goes	go	VERB
fnp-5842	297	90	,	,	PUNCT
fnp-5842	297	91	the	the	DET
fnp-5842	297	92	netherlands	netherlands	PROPN
fnp-5842	297	93	bacterial	bacterial	ADJ
fnp-5842	297	94	infections	infection	NOUN
fnp-5842	297	95	of	of	ADP
fnp-5842	297	96	the	the	DET
fnp-5842	297	97	central	central	ADJ
fnp-5842	297	98	nervous	nervous	ADJ
fnp-5842	297	99	system	system	NOUN
fnp-5842	297	100	(	(	PUNCT
fnp-5842	297	101	cns	cns	NOUN
fnp-5842	297	102	)	)	PUNCT
fnp-5842	297	103	are	be	AUX
fnp-5842	297	104	severe	severe	ADJ
fnp-5842	297	105	and	and	CCONJ
fnp-5842	297	106	potentially	potentially	ADV
fnp-5842	297	107	fatal	fatal	ADJ
fnp-5842	297	108	diseases	disease	NOUN
fnp-5842	297	109	.	.	PUNCT
fnp-5842	298	1	early	early	ADJ
fnp-5842	298	2	detection	detection	NOUN
fnp-5842	298	3	of	of	ADP
fnp-5842	298	4	causative	causative	ADJ
fnp-5842	298	5	pathogens	pathogen	NOUN
fnp-5842	298	6	is	be	AUX
fnp-5842	298	7	crucial	crucial	ADJ
fnp-5842	298	8	for	for	ADP
fnp-5842	298	9	the	the	DET
fnp-5842	298	10	rapid	rapid	ADJ
fnp-5842	298	11	administration	administration	NOUN
fnp-5842	298	12	of	of	ADP
fnp-5842	298	13	a	a	DET
fnp-5842	298	14	tailored	tailor	VERB
fnp-5842	298	15	antibiotic	antibiotic	ADJ
fnp-5842	298	16	regime	regime	NOUN
fnp-5842	298	17	.	.	PUNCT
fnp-5842	299	1	routine	routine	ADJ
fnp-5842	299	2	neuropathology	neuropathology	NOUN
fnp-5842	299	3	diagnostics	diagnostic	NOUN
fnp-5842	299	4	is	be	AUX
fnp-5842	299	5	typically	typically	ADV
fnp-5842	299	6	limited	limit	VERB
fnp-5842	299	7	to	to	ADP
fnp-5842	299	8	histological	histological	ADJ
fnp-5842	299	9	staining	stain	VERB
fnp-5842	299	10	and	and	CCONJ
fnp-5842	299	11	microbiological	microbiological	ADJ
fnp-5842	299	12	culture	culture	NOUN
fnp-5842	299	13	,	,	PUNCT
fnp-5842	299	14	which	which	PRON
fnp-5842	299	15	are	be	AUX
fnp-5842	299	16	time	time	NOUN
fnp-5842	299	17	consuming	consume	VERB
fnp-5842	299	18	and	and	CCONJ
fnp-5842	299	19	result	result	VERB
fnp-5842	299	20	in	in	ADP
fnp-5842	299	21	false	false	ADJ
fnp-5842	299	22	-	-	PUNCT
fnp-5842	299	23	negative	negative	ADJ
fnp-5842	299	24	results	result	NOUN
fnp-5842	299	25	in	in	ADP
fnp-5842	299	26	one	one	NUM
fnp-5842	299	27	-	-	PUNCT
fnp-5842	299	28	third	third	NOUN
fnp-5842	299	29	of	of	ADP
fnp-5842	299	30	cases	case	NOUN
fnp-5842	299	31	.	.	PUNCT
fnp-5842	300	1	metagenomic	metagenomic	ADJ
fnp-5842	300	2	sequencing	sequencing	NOUN
fnp-5842	300	3	of	of	ADP
fnp-5842	300	4	the	the	DET
fnp-5842	300	5	bacterial	bacterial	ADJ
fnp-5842	300	6	16s	16s	PROPN
fnp-5842	300	7	rrna	rrna	PROPN
fnp-5842	300	8	gene	gene	NOUN
fnp-5842	300	9	offers	offer	VERB
fnp-5842	300	10	a	a	DET
fnp-5842	300	11	rapid	rapid	ADJ
fnp-5842	300	12	and	and	CCONJ
fnp-5842	300	13	unbiased	unbiased	ADJ
fnp-5842	300	14	alternative	alternative	NOUN
fnp-5842	300	15	.	.	PUNCT
fnp-5842	301	1	in	in	ADP
fnp-5842	301	2	this	this	DET
fnp-5842	301	3	study	study	NOUN
fnp-5842	301	4	,	,	PUNCT
fnp-5842	301	5	we	we	PRON
fnp-5842	301	6	present	present	VERB
fnp-5842	301	7	a	a	DET
fnp-5842	301	8	method	method	NOUN
fnp-5842	301	9	for	for	ADP
fnp-5842	301	10	detecting	detect	VERB
fnp-5842	301	11	bacterial	bacterial	ADJ
fnp-5842	301	12	pathogens	pathogen	NOUN
fnp-5842	301	13	in	in	ADP
fnp-5842	301	14	neuropathology	neuropathology	NOUN
fnp-5842	301	15	specimens	specimen	NOUN
fnp-5842	301	16	using	use	VERB
fnp-5842	301	17	ultra	ultra	ADJ
fnp-5842	301	18	-	-	ADJ
fnp-5842	301	19	rapid	rapid	ADJ
fnp-5842	301	20	pcr	pcr	NOUN
fnp-5842	301	21	combined	combine	VERB
fnp-5842	301	22	with	with	ADP
fnp-5842	301	23	nanopore	nanopore	ADJ
fnp-5842	301	24	sequencing	sequencing	NOUN
fnp-5842	301	25	of	of	ADP
fnp-5842	301	26	16s	16	NOUN
fnp-5842	301	27	rdna	rdna	NOUN
fnp-5842	301	28	amplicons	amplicon	NOUN
fnp-5842	301	29	.	.	PUNCT
fnp-5842	302	1	for	for	ADP
fnp-5842	302	2	protocol	protocol	NOUN
fnp-5842	302	3	optimization	optimization	NOUN
fnp-5842	302	4	,	,	PUNCT
fnp-5842	302	5	a	a	DET
fnp-5842	302	6	microbial	microbial	ADJ
fnp-5842	302	7	community	community	NOUN
fnp-5842	302	8	standard	standard	NOUN
fnp-5842	302	9	and	and	CCONJ
fnp-5842	302	10	varying	vary	VERB
fnp-5842	302	11	concentrations	concentration	NOUN
fnp-5842	302	12	(	(	PUNCT
fnp-5842	302	13	5	5	NUM
fnp-5842	302	14	 	 	SPACE
fnp-5842	302	15	pg	pg	NOUN
fnp-5842	302	16	to	to	ADP
fnp-5842	302	17	5	5	NUM
fnp-5842	302	18	 	 	SPACE
fnp-5842	302	19	ng	ng	PROPN
fnp-5842	302	20	)	)	PUNCT
fnp-5842	302	21	of	of	ADP
fnp-5842	302	22	gdna	gdna	ADV
fnp-5842	302	23	from	from	ADP
fnp-5842	302	24	e.	e.	PROPN
fnp-5842	302	25	coli	coli	PROPN
fnp-5842	302	26	and	and	CCONJ
fnp-5842	302	27	s.	s.	PROPN
fnp-5842	302	28	aureus	aureus	PROPN
fnp-5842	302	29	were	be	AUX
fnp-5842	302	30	used	use	VERB
fnp-5842	302	31	.	.	PUNCT
fnp-5842	303	1	ten	ten	NUM
fnp-5842	303	2	ffpe	ffpe	NOUN
fnp-5842	303	3	samples	sample	NOUN
fnp-5842	303	4	with	with	ADP
fnp-5842	303	5	known	know	VERB
fnp-5842	303	6	bacterial	bacterial	ADJ
fnp-5842	303	7	cns	cns	NOUN
fnp-5842	303	8	infections	infection	NOUN
fnp-5842	303	9	were	be	AUX
fnp-5842	303	10	retrieved	retrieve	VERB
fnp-5842	303	11	from	from	ADP
fnp-5842	303	12	the	the	DET
fnp-5842	303	13	institute	institute	PROPN
fnp-5842	303	14	of	of	ADP
fnp-5842	303	15	neuropathology	neuropathology	NOUN
fnp-5842	303	16	münster	münster	NOUN
fnp-5842	303	17	.	.	PUNCT
fnp-5842	304	1	after	after	ADP
fnp-5842	304	2	dna	dna	PROPN
fnp-5842	304	3	isolation	isolation	NOUN
fnp-5842	304	4	,	,	PUNCT
fnp-5842	304	5	library	library	ADJ
fnp-5842	304	6	preparation	preparation	NOUN
fnp-5842	304	7	was	be	AUX
fnp-5842	304	8	performed	perform	VERB
fnp-5842	304	9	using	use	VERB
fnp-5842	304	10	classic	classic	ADJ
fnp-5842	304	11	pcr	pcr	NOUN
fnp-5842	304	12	and	and	CCONJ
fnp-5842	304	13	nextgenpcr	nextgenpcr	ADV
fnp-5842	304	14	with	with	ADP
fnp-5842	304	15	four	four	NUM
fnp-5842	304	16	primer	primer	NOUN
fnp-5842	304	17	pairs	pair	NOUN
fnp-5842	304	18	covering	cover	VERB
fnp-5842	304	19	the	the	DET
fnp-5842	304	20	variable	variable	ADJ
fnp-5842	304	21	regions	region	NOUN
fnp-5842	304	22	v3	v3	PROPN
fnp-5842	304	23	–	–	PUNCT
fnp-5842	304	24	v7	v7	NOUN
fnp-5842	304	25	of	of	ADP
fnp-5842	304	26	the	the	DET
fnp-5842	304	27	16s	16s	PROPN
fnp-5842	304	28	rrna	rrna	PROPN
fnp-5842	304	29	gene	gene	NOUN
fnp-5842	304	30	.	.	PUNCT
fnp-5842	305	1	amplicons	amplicon	NOUN
fnp-5842	305	2	were	be	AUX
fnp-5842	305	3	sequenced	sequence	VERB
fnp-5842	305	4	on	on	ADP
fnp-5842	305	5	a	a	DET
fnp-5842	305	6	minion	minion	NOUN
fnp-5842	305	7	device	device	NOUN
fnp-5842	305	8	and	and	CCONJ
fnp-5842	305	9	data	datum	NOUN
fnp-5842	305	10	was	be	AUX
fnp-5842	305	11	analysed	analyse	VERB
fnp-5842	305	12	with	with	ADP
fnp-5842	305	13	epi2me	epi2me	PROPN
fnp-5842	305	14	,	,	PUNCT
fnp-5842	305	15	maba16s	maba16	NOUN
fnp-5842	305	16	and	and	CCONJ
fnp-5842	305	17	emu	emu	PROPN
fnp-5842	305	18	.	.	PROPN
fnp-5842	306	1	nextgenpcr	nextgenpcr	ADV
fnp-5842	306	2	followed	follow	VERB
fnp-5842	306	3	by	by	ADP
fnp-5842	306	4	nanopore	nanopore	ADV
fnp-5842	306	5	sequencing	sequencing	NOUN
fnp-5842	306	6	identified	identify	VERB
fnp-5842	306	7	bacterial	bacterial	ADJ
fnp-5842	306	8	taxa	taxa	NOUN
fnp-5842	306	9	more	more	ADV
fnp-5842	306	10	accurately	accurately	ADV
fnp-5842	306	11	(	(	PUNCT
fnp-5842	306	12	64	64	NUM
fnp-5842	306	13	 	 	SPACE
fnp-5842	306	14	%	%	NOUN
fnp-5842	306	15	vs.	vs.	ADP
fnp-5842	306	16	26	26	NUM
fnp-5842	306	17	 	 	SPACE
fnp-5842	306	18	%	%	NOUN
fnp-5842	306	19	correct	correct	ADJ
fnp-5842	306	20	hits	hit	NOUN
fnp-5842	306	21	,	,	PUNCT
fnp-5842	306	22	p	p	X
fnp-5842	306	23	 	 	SPACE
fnp-5842	306	24	<	<	X
fnp-5842	306	25	 	 	SPACE
fnp-5842	306	26	0.001	0.001	NUM
fnp-5842	306	27	,	,	PUNCT
fnp-5842	306	28	t	t	NOUN
fnp-5842	306	29	-	-	PUNCT
fnp-5842	306	30	test	test	NOUN
fnp-5842	306	31	)	)	PUNCT
fnp-5842	306	32	.	.	PUNCT
fnp-5842	307	1	compared	compare	VERB
fnp-5842	307	2	to	to	ADP
fnp-5842	307	3	classic	classic	ADJ
fnp-5842	307	4	pcr	pcr	NOUN
fnp-5842	307	5	,	,	PUNCT
fnp-5842	307	6	the	the	DET
fnp-5842	307	7	optimized	optimize	VERB
fnp-5842	307	8	nextgenpcr	nextgenpcr	ADJ
fnp-5842	307	9	protocol	protocol	NOUN
fnp-5842	307	10	significantly	significantly	ADV
fnp-5842	307	11	reduced	reduce	VERB
fnp-5842	307	12	the	the	DET
fnp-5842	307	13	amplification	amplification	NOUN
fnp-5842	307	14	time	time	NOUN
fnp-5842	307	15	from	from	ADP
fnp-5842	307	16	165	165	NUM
fnp-5842	307	17	to	to	PART
fnp-5842	307	18	35	35	NUM
fnp-5842	307	19	minutes	minute	NOUN
fnp-5842	307	20	.	.	PUNCT
fnp-5842	308	1	in	in	ADP
fnp-5842	308	2	conclusion	conclusion	NOUN
fnp-5842	308	3	,	,	PUNCT
fnp-5842	308	4	nextgenpcr	nextgenpcr	ADV
fnp-5842	308	5	of	of	ADP
fnp-5842	308	6	16s	16s	PROPN
fnp-5842	308	7	rdna	rdna	PROPN
fnp-5842	308	8	followed	follow	VERB
fnp-5842	308	9	by	by	ADP
fnp-5842	308	10	nanopore	nanopore	ADJ
fnp-5842	308	11	sequencing	sequencing	NOUN
fnp-5842	308	12	offers	offer	VERB
fnp-5842	308	13	an	an	DET
fnp-5842	308	14	ultra	ultra	ADJ
fnp-5842	308	15	-	-	ADJ
fnp-5842	308	16	rapid	rapid	ADJ
fnp-5842	308	17	method	method	NOUN
fnp-5842	308	18	for	for	ADP
fnp-5842	308	19	detecting	detect	VERB
fnp-5842	308	20	bacteria	bacteria	NOUN
fnp-5842	308	21	in	in	ADP
fnp-5842	308	22	neuropathology	neuropathology	NOUN
fnp-5842	308	23	specimens	specimen	NOUN
fnp-5842	308	24	.	.	PUNCT
fnp-5842	309	1	further	further	ADJ
fnp-5842	309	2	investigation	investigation	NOUN
fnp-5842	309	3	of	of	ADP
fnp-5842	309	4	a	a	DET
fnp-5842	309	5	larger	large	ADJ
fnp-5842	309	6	cohort	cohort	NOUN
fnp-5842	309	7	including	include	VERB
fnp-5842	309	8	cerebrospinal	cerebrospinal	ADJ
fnp-5842	309	9	fluid	fluid	NOUN
fnp-5842	309	10	samples	sample	NOUN
fnp-5842	309	11	is	be	AUX
fnp-5842	309	12	warranted	warrant	VERB
fnp-5842	309	13	.	.	PUNCT
fnp-5842	310	1	p25	p25	PROPN
fnp-5842	310	2	free	free	ADJ
fnp-5842	310	3	neuropathol	neuropathol	NOUN
fnp-5842	310	4	5:19:38	5:19:38	NUM
fnp-5842	310	5	ccnv	ccnv	NOUN
fnp-5842	310	6	:	:	PUNCT
fnp-5842	310	7	r	r	NOUN
fnp-5842	310	8	package	package	NOUN
fnp-5842	310	9	for	for	ADP
fnp-5842	310	10	enhanced	enhanced	ADJ
fnp-5842	310	11	cumulative	cumulative	ADJ
fnp-5842	310	12	copy	copy	NOUN
fnp-5842	310	13	number	number	NOUN
fnp-5842	310	14	variation	variation	NOUN
fnp-5842	310	15	analysis	analysis	NOUN
fnp-5842	310	16	antonia	antonia	PROPN
fnp-5842	310	17	gocke1,2	gocke1,2	PROPN
fnp-5842	310	18	,	,	PUNCT
fnp-5842	310	19	yannis	yannis	PROPN
fnp-5842	310	20	schumann3	schumann3	PROPN
fnp-5842	310	21	,	,	PUNCT
fnp-5842	310	22	jelena	jelena	PROPN
fnp-5842	310	23	navolic1	navolic1	PROPN
fnp-5842	310	24	,	,	PUNCT
fnp-5842	310	25	melanie	melanie	PROPN
fnp-5842	310	26	schoof4,5	schoof4,5	PROPN
fnp-5842	310	27	,	,	PUNCT
fnp-5842	310	28	matthias	matthias	PROPN
fnp-5842	310	29	dottermusch1,6	dottermusch1,6	PROPN
fnp-5842	310	30	,	,	PUNCT
fnp-5842	310	31	julia	julia	PROPN
fnp-5842	310	32	e.	e.	PROPN
fnp-5842	310	33	neumann1,6	neumann1,6	PROPN
fnp-5842	310	34	1	1	NUM
fnp-5842	310	35	center	center	NOUN
fnp-5842	310	36	for	for	ADP
fnp-5842	310	37	molecular	molecular	ADJ
fnp-5842	310	38	neurobiology	neurobiology	NOUN
fnp-5842	310	39	hamburg	hamburg	PROPN
fnp-5842	310	40	(	(	PUNCT
fnp-5842	310	41	zmnh	zmnh	PROPN
fnp-5842	310	42	)	)	PUNCT
fnp-5842	310	43	,	,	PUNCT
fnp-5842	310	44	university	university	NOUN
fnp-5842	310	45	medical	medical	ADJ
fnp-5842	310	46	center	center	PROPN
fnp-5842	310	47	hamburg	hamburg	PROPN
fnp-5842	310	48	-	-	PUNCT
fnp-5842	310	49	eppendorf	eppendorf	PROPN
fnp-5842	310	50	,	,	PUNCT
fnp-5842	310	51	hamburg	hamburg	PROPN
fnp-5842	310	52	,	,	PUNCT
fnp-5842	310	53	germany	germany	PROPN
fnp-5842	310	54	2	2	NUM
fnp-5842	310	55	section	section	NOUN
fnp-5842	310	56	of	of	ADP
fnp-5842	310	57	mass	mass	ADJ
fnp-5842	310	58	spectrometric	spectrometric	ADJ
fnp-5842	310	59	proteomics	proteomic	NOUN
fnp-5842	310	60	,	,	PUNCT
fnp-5842	310	61	university	university	NOUN
fnp-5842	310	62	medical	medical	ADJ
fnp-5842	310	63	center	center	PROPN
fnp-5842	310	64	hamburg	hamburg	PROPN
fnp-5842	310	65	-	-	PUNCT
fnp-5842	310	66	eppendorf	eppendorf	PROPN
fnp-5842	310	67	,	,	PUNCT
fnp-5842	310	68	hamburg	hamburg	PROPN
fnp-5842	310	69	,	,	PUNCT
fnp-5842	310	70	germany	germany	PROPN
fnp-5842	310	71	3	3	NUM
fnp-5842	310	72	chair	chair	NOUN
fnp-5842	310	73	for	for	ADP
fnp-5842	310	74	high	high	ADJ
fnp-5842	310	75	performance	performance	NOUN
fnp-5842	310	76	computing	computing	NOUN
fnp-5842	310	77	,	,	PUNCT
fnp-5842	310	78	helmut	helmut	PROPN
fnp-5842	310	79	-	-	PUNCT
fnp-5842	310	80	schmidt	schmidt	PROPN
fnp-5842	310	81	university	university	PROPN
fnp-5842	310	82	,	,	PUNCT
fnp-5842	310	83	hamburg	hamburg	PROPN
fnp-5842	310	84	,	,	PUNCT
fnp-5842	310	85	germany	germany	PROPN
fnp-5842	310	86	4	4	NUM
fnp-5842	310	87	research	research	PROPN
fnp-5842	310	88	institute	institute	NOUN
fnp-5842	310	89	children	child	NOUN
fnp-5842	310	90	’s	’s	PART
fnp-5842	310	91	cancer	cancer	NOUN
fnp-5842	310	92	center	center	PROPN
fnp-5842	310	93	hamburg	hamburg	PROPN
fnp-5842	310	94	,	,	PUNCT
fnp-5842	310	95	hamburg	hamburg	PROPN
fnp-5842	310	96	,	,	PUNCT
fnp-5842	310	97	germany	germany	PROPN
fnp-5842	310	98	5	5	NUM
fnp-5842	310	99	department	department	NOUN
fnp-5842	310	100	of	of	ADP
fnp-5842	310	101	pediatric	pediatric	ADJ
fnp-5842	310	102	hematology	hematology	NOUN
fnp-5842	310	103	and	and	CCONJ
fnp-5842	310	104	oncology	oncology	NOUN
fnp-5842	310	105	,	,	PUNCT
fnp-5842	310	106	university	university	NOUN
fnp-5842	310	107	medical	medical	ADJ
fnp-5842	310	108	center	center	PROPN
fnp-5842	310	109	hamburg	hamburg	PROPN
fnp-5842	310	110	-	-	PUNCT
fnp-5842	310	111	eppendorf	eppendorf	PROPN
fnp-5842	310	112	,	,	PUNCT
fnp-5842	310	113	hamburg	hamburg	PROPN
fnp-5842	310	114	,	,	PUNCT
fnp-5842	310	115	germany	germany	PROPN
fnp-5842	310	116	6	6	NUM
fnp-5842	310	117	institute	institute	PROPN
fnp-5842	310	118	of	of	ADP
fnp-5842	310	119	neuropathology	neuropathology	NOUN
fnp-5842	310	120	,	,	PUNCT
fnp-5842	310	121	university	university	NOUN
fnp-5842	310	122	medical	medical	ADJ
fnp-5842	310	123	center	center	PROPN
fnp-5842	310	124	hamburg	hamburg	PROPN
fnp-5842	310	125	-	-	PUNCT
fnp-5842	310	126	eppendorf	eppendorf	PROPN
fnp-5842	310	127	,	,	PUNCT
fnp-5842	310	128	hamburg	hamburg	PROPN
fnp-5842	310	129	,	,	PUNCT
fnp-5842	310	130	germany	germany	PROPN
fnp-5842	310	131	copy	copy	VERB
fnp-5842	310	132	number	number	NOUN
fnp-5842	310	133	variation	variation	NOUN
fnp-5842	310	134	(	(	PUNCT
fnp-5842	310	135	cnv	cnv	NOUN
fnp-5842	310	136	)	)	PUNCT
fnp-5842	310	137	analysis	analysis	NOUN
fnp-5842	310	138	is	be	AUX
fnp-5842	310	139	the	the	DET
fnp-5842	310	140	study	study	NOUN
fnp-5842	310	141	of	of	ADP
fnp-5842	310	142	genomic	genomic	NOUN
fnp-5842	310	143	alterations	alteration	NOUN
fnp-5842	310	144	resulting	result	VERB
fnp-5842	310	145	in	in	ADP
fnp-5842	310	146	an	an	DET
fnp-5842	310	147	abnormal	abnormal	ADJ
fnp-5842	310	148	copy	copy	NOUN
fnp-5842	310	149	number	number	NOUN
fnp-5842	310	150	of	of	ADP
fnp-5842	310	151	genes	gene	NOUN
fnp-5842	310	152	,	,	PUNCT
fnp-5842	310	153	chromosomal	chromosomal	ADJ
fnp-5842	310	154	segments	segment	NOUN
fnp-5842	310	155	or	or	CCONJ
fnp-5842	310	156	whole	whole	ADJ
fnp-5842	310	157	chromosomes	chromosome	NOUN
fnp-5842	310	158	.	.	PUNCT
fnp-5842	311	1	the	the	DET
fnp-5842	311	2	identification	identification	NOUN
fnp-5842	311	3	of	of	ADP
fnp-5842	311	4	chromosomal	chromosomal	ADJ
fnp-5842	311	5	aberrations	aberration	NOUN
fnp-5842	311	6	can	can	AUX
fnp-5842	311	7	help	help	AUX
fnp-5842	311	8	identify	identify	VERB
fnp-5842	311	9	targetable	targetable	ADJ
fnp-5842	311	10	proteins	protein	NOUN
fnp-5842	311	11	or	or	CCONJ
fnp-5842	311	12	markers	marker	NOUN
fnp-5842	311	13	for	for	ADP
fnp-5842	311	14	specific	specific	ADJ
fnp-5842	311	15	tumour	tumour	NOUN
fnp-5842	311	16	entities	entity	NOUN
fnp-5842	311	17	(	(	PUNCT
fnp-5842	311	18	e.g.	e.g.	ADV
fnp-5842	311	19	the	the	DET
fnp-5842	311	20	mycn	mycn	NOUN
fnp-5842	311	21	amplification	amplification	NOUN
fnp-5842	311	22	in	in	ADP
fnp-5842	311	23	spinal	spinal	ADJ
fnp-5842	311	24	ependymomas	ependymoma	NOUN
fnp-5842	311	25	,	,	PUNCT
fnp-5842	311	26	mycn	mycn	NOUN
fnp-5842	311	27	-	-	PUNCT
fnp-5842	311	28	amplified	amplify	VERB
fnp-5842	311	29	or	or	CCONJ
fnp-5842	311	30	the	the	DET
fnp-5842	311	31	loss	loss	NOUN
fnp-5842	311	32	of	of	ADP
fnp-5842	311	33	smarcb1	smarcb1	NOUN
fnp-5842	311	34	in	in	ADP
fnp-5842	311	35	atypical	atypical	ADJ
fnp-5842	311	36	teratoid	teratoid	NOUN
fnp-5842	311	37	/	/	SYM
fnp-5842	311	38	rhabdoid	rhabdoid	NOUN
fnp-5842	311	39	tumours	tumours	PROPN
fnp-5842	311	40	)	)	PUNCT
fnp-5842	311	41	.	.	PUNCT
fnp-5842	312	1	cnv	cnv	PROPN
fnp-5842	312	2	information	information	NOUN
fnp-5842	312	3	can	can	AUX
fnp-5842	312	4	be	be	AUX
fnp-5842	312	5	derived	derive	VERB
fnp-5842	312	6	from	from	ADP
fnp-5842	312	7	global	global	ADJ
fnp-5842	312	8	dna	dna	PROPN
fnp-5842	312	9	methylation	methylation	PROPN
fnp-5842	312	10	data	datum	NOUN
fnp-5842	312	11	,	,	PUNCT
fnp-5842	312	12	which	which	PRON
fnp-5842	312	13	has	have	AUX
fnp-5842	312	14	become	become	VERB
fnp-5842	312	15	an	an	DET
fnp-5842	312	16	integral	integral	ADJ
fnp-5842	312	17	part	part	NOUN
fnp-5842	312	18	of	of	ADP
fnp-5842	312	19	tumor	tumor	NOUN
fnp-5842	312	20	diagnostics	diagnostic	NOUN
fnp-5842	312	21	.	.	PUNCT
fnp-5842	313	1	cnvs	cnvs	PROPN
fnp-5842	313	2	can	can	AUX
fnp-5842	313	3	help	help	VERB
fnp-5842	313	4	in	in	ADP
fnp-5842	313	5	or	or	CCONJ
fnp-5842	313	6	even	even	ADV
fnp-5842	313	7	guide	guide	VERB
fnp-5842	313	8	tumor	tumor	NOUN
fnp-5842	313	9	classification	classification	NOUN
fnp-5842	313	10	and	and	CCONJ
fnp-5842	313	11	the	the	DET
fnp-5842	313	12	number	number	NOUN
fnp-5842	313	13	of	of	ADP
fnp-5842	313	14	available	available	ADJ
fnp-5842	313	15	data	datum	NOUN
fnp-5842	313	16	constantly	constantly	ADV
fnp-5842	313	17	increases	increase	VERB
fnp-5842	313	18	.	.	PUNCT
fnp-5842	314	1	in	in	ADP
fnp-5842	314	2	order	order	NOUN
fnp-5842	314	3	to	to	PART
fnp-5842	314	4	characterize	characterize	VERB
fnp-5842	314	5	cnvs	cnvs	NOUN
fnp-5842	314	6	in	in	ADP
fnp-5842	314	7	large	large	ADJ
fnp-5842	314	8	datasets	dataset	NOUN
fnp-5842	314	9	comprising	comprise	VERB
fnp-5842	314	10	tumor	tumor	NOUN
fnp-5842	314	11	subgroups	subgroup	NOUN
fnp-5842	314	12	or	or	CCONJ
fnp-5842	314	13	types	type	NOUN
fnp-5842	314	14	we	we	PRON
fnp-5842	314	15	developed	develop	VERB
fnp-5842	314	16	ccnv	ccnv	NOUN
fnp-5842	314	17	,	,	PUNCT
fnp-5842	314	18	a	a	DET
fnp-5842	314	19	tool	tool	NOUN
fnp-5842	314	20	for	for	ADP
fnp-5842	314	21	fast	fast	ADJ
fnp-5842	314	22	,	,	PUNCT
fnp-5842	314	23	accurate	accurate	ADJ
fnp-5842	314	24	and	and	CCONJ
fnp-5842	314	25	efficient	efficient	ADJ
fnp-5842	314	26	cumulative	cumulative	ADJ
fnp-5842	314	27	cnv	cnv	PROPN
fnp-5842	314	28	analyses	analysis	NOUN
fnp-5842	314	29	.	.	PUNCT
fnp-5842	315	1	ccnv	ccnv	NOUN
fnp-5842	315	2	is	be	AUX
fnp-5842	315	3	an	an	DET
fnp-5842	315	4	r	r	NOUN
fnp-5842	315	5	package	package	NOUN
fnp-5842	315	6	that	that	PRON
fnp-5842	315	7	integrates	integrate	VERB
fnp-5842	315	8	two	two	NUM
fnp-5842	315	9	main	main	ADJ
fnp-5842	315	10	algorithms	algorithm	NOUN
fnp-5842	315	11	for	for	ADP
fnp-5842	315	12	the	the	DET
fnp-5842	315	13	segmentation	segmentation	NOUN
fnp-5842	315	14	of	of	ADP
fnp-5842	315	15	inferred	infer	VERB
fnp-5842	315	16	copy	copy	NOUN
fnp-5842	315	17	number	number	NOUN
fnp-5842	315	18	data	datum	NOUN
fnp-5842	315	19	from	from	ADP
fnp-5842	315	20	methylation	methylation	NOUN
fnp-5842	315	21	data	datum	NOUN
fnp-5842	315	22	;	;	PUNCT
fnp-5842	315	23	the	the	DET
fnp-5842	315	24	circular	circular	ADJ
fnp-5842	315	25	binary	binary	ADJ
fnp-5842	315	26	segmentation	segmentation	NOUN
fnp-5842	315	27	integrated	integrate	VERB
fnp-5842	315	28	in	in	ADP
fnp-5842	315	29	conumee	conumee	PROPN
fnp-5842	315	30	/	/	SYM
fnp-5842	315	31	conumee2.0	conumee2.0	PROPN
fnp-5842	315	32	(	(	PUNCT
fnp-5842	315	33	hovestadt	hovestadt	NOUN
fnp-5842	315	34	,	,	PUNCT
fnp-5842	315	35	zapatka	zapatka	PROPN
fnp-5842	315	36	(	(	PUNCT
fnp-5842	315	37	2015	2015	NUM
fnp-5842	315	38	)	)	PUNCT
fnp-5842	315	39	,	,	PUNCT
fnp-5842	315	40	daekanas	daekana	NOUN
fnp-5842	315	41	(	(	PUNCT
fnp-5842	315	42	2024	2024	NUM
fnp-5842	315	43	)	)	PUNCT
fnp-5842	315	44	)	)	PUNCT
fnp-5842	315	45	and	and	CCONJ
fnp-5842	315	46	the	the	DET
fnp-5842	315	47	piecewise	piecewise	NOUN
fnp-5842	315	48	curve	curve	NOUN
fnp-5842	315	49	fit	fit	ADJ
fnp-5842	315	50	algorithm	algorithm	NOUN
fnp-5842	315	51	(	(	PUNCT
fnp-5842	315	52	nilsen	nilsen	PROPN
fnp-5842	315	53	(	(	PUNCT
fnp-5842	315	54	2012	2012	NUM
fnp-5842	315	55	)	)	PUNCT
fnp-5842	315	56	)	)	PUNCT
fnp-5842	315	57	.	.	PUNCT
fnp-5842	316	1	the	the	DET
fnp-5842	316	2	package	package	NOUN
fnp-5842	316	3	is	be	AUX
fnp-5842	316	4	compatible	compatible	ADJ
fnp-5842	316	5	with	with	ADP
fnp-5842	316	6	all	all	DET
fnp-5842	316	7	major	major	ADJ
fnp-5842	316	8	available	available	ADJ
fnp-5842	316	9	dna	dna	PROPN
fnp-5842	316	10	methylation	methylation	NOUN
fnp-5842	316	11	chips	chip	NOUN
fnp-5842	316	12	(	(	PUNCT
fnp-5842	316	13	450k	450k	NOUN
fnp-5842	316	14	,	,	PUNCT
fnp-5842	316	15	epic	epic	ADJ
fnp-5842	316	16	;	;	PUNCT
fnp-5842	316	17	epicv2	epicv2	PROPN
fnp-5842	316	18	,	,	PUNCT
fnp-5842	316	19	mouse	mouse	NOUN
fnp-5842	316	20	chip	chip	NOUN
fnp-5842	316	21	)	)	PUNCT
fnp-5842	316	22	and	and	CCONJ
fnp-5842	316	23	can	can	AUX
fnp-5842	316	24	automatically	automatically	ADV
fnp-5842	316	25	read	read	VERB
fnp-5842	316	26	array	array	NOUN
fnp-5842	316	27	data	datum	NOUN
fnp-5842	316	28	from	from	ADP
fnp-5842	316	29	.idat	.idat	NOUN
fnp-5842	316	30	files	file	NOUN
fnp-5842	316	31	.	.	PUNCT
fnp-5842	317	1	each	each	DET
fnp-5842	317	2	segmentation	segmentation	NOUN
fnp-5842	317	3	algorithm	algorithm	NOUN
fnp-5842	317	4	produces	produce	VERB
fnp-5842	317	5	one	one	NUM
fnp-5842	317	6	intensity	intensity	NOUN
fnp-5842	317	7	plot	plot	NOUN
fnp-5842	317	8	,	,	PUNCT
fnp-5842	317	9	representing	represent	VERB
fnp-5842	317	10	how	how	SCONJ
fnp-5842	317	11	strong	strong	ADJ
fnp-5842	317	12	aberrations	aberration	NOUN
fnp-5842	317	13	are	be	AUX
fnp-5842	317	14	across	across	ADP
fnp-5842	317	15	the	the	DET
fnp-5842	317	16	cohort	cohort	NOUN
fnp-5842	317	17	,	,	PUNCT
fnp-5842	317	18	and	and	CCONJ
fnp-5842	317	19	one	one	NUM
fnp-5842	317	20	frequency	frequency	NOUN
fnp-5842	317	21	plot	plot	NOUN
fnp-5842	317	22	,	,	PUNCT
fnp-5842	317	23	representing	represent	VERB
fnp-5842	317	24	how	how	SCONJ
fnp-5842	317	25	often	often	ADV
fnp-5842	317	26	an	an	DET
fnp-5842	317	27	aberration	aberration	NOUN
fnp-5842	317	28	occurs	occur	VERB
fnp-5842	317	29	.	.	PUNCT
fnp-5842	318	1	while	while	SCONJ
fnp-5842	318	2	the	the	DET
fnp-5842	318	3	circular	circular	ADJ
fnp-5842	318	4	binary	binary	ADJ
fnp-5842	318	5	segmentation	segmentation	NOUN
fnp-5842	318	6	is	be	AUX
fnp-5842	318	7	applied	apply	VERB
fnp-5842	318	8	consecutively	consecutively	ADV
fnp-5842	318	9	to	to	ADP
fnp-5842	318	10	each	each	DET
fnp-5842	318	11	sample	sample	NOUN
fnp-5842	318	12	,	,	PUNCT
fnp-5842	318	13	the	the	DET
fnp-5842	318	14	piecewise	piecewise	NOUN
fnp-5842	318	15	curve	curve	NOUN
fnp-5842	318	16	fit	fit	ADJ
fnp-5842	318	17	algorithm	algorithm	NOUN
fnp-5842	318	18	can	can	AUX
fnp-5842	318	19	be	be	AUX
fnp-5842	318	20	applied	apply	VERB
fnp-5842	318	21	to	to	ADP
fnp-5842	318	22	all	all	DET
fnp-5842	318	23	samples	sample	NOUN
fnp-5842	318	24	simultaneously	simultaneously	ADV
fnp-5842	318	25	,	,	PUNCT
fnp-5842	318	26	achieving	achieve	VERB
fnp-5842	318	27	a	a	DET
fnp-5842	318	28	significant	significant	ADJ
fnp-5842	318	29	decrease	decrease	NOUN
fnp-5842	318	30	in	in	ADP
fnp-5842	318	31	runtime	runtime	NOUN
fnp-5842	318	32	.	.	PUNCT
fnp-5842	319	1	the	the	DET
fnp-5842	319	2	latter	latter	ADJ
fnp-5842	319	3	further	further	ADJ
fnp-5842	319	4	extracts	extract	NOUN
fnp-5842	319	5	the	the	DET
fnp-5842	319	6	main	main	ADJ
fnp-5842	319	7	aberrations	aberration	NOUN
fnp-5842	319	8	of	of	ADP
fnp-5842	319	9	the	the	DET
fnp-5842	319	10	investigated	investigate	VERB
fnp-5842	319	11	samples	sample	NOUN
fnp-5842	319	12	,	,	PUNCT
fnp-5842	319	13	making	make	VERB
fnp-5842	319	14	it	it	PRON
fnp-5842	319	15	particularly	particularly	ADV
fnp-5842	319	16	suitable	suitable	ADJ
fnp-5842	319	17	for	for	ADP
fnp-5842	319	18	large	large	ADJ
fnp-5842	319	19	datasets	dataset	NOUN
fnp-5842	319	20	.	.	PUNCT
fnp-5842	320	1	with	with	ADP
fnp-5842	320	2	different	different	ADJ
fnp-5842	320	3	selectable	selectable	ADJ
fnp-5842	320	4	segmentation	segmentation	NOUN
fnp-5842	320	5	algorithms	algorithm	NOUN
fnp-5842	320	6	and	and	CCONJ
fnp-5842	320	7	parameters	parameter	NOUN
fnp-5842	320	8	the	the	DET
fnp-5842	320	9	ccnv	ccnv	PROPN
fnp-5842	320	10	package	package	NOUN
fnp-5842	320	11	is	be	AUX
fnp-5842	320	12	a	a	DET
fnp-5842	320	13	flexible	flexible	ADJ
fnp-5842	320	14	and	and	CCONJ
fnp-5842	320	15	efficient	efficient	ADJ
fnp-5842	320	16	tool	tool	NOUN
fnp-5842	320	17	to	to	PART
fnp-5842	320	18	generate	generate	VERB
fnp-5842	320	19	cumulative	cumulative	ADJ
fnp-5842	320	20	cnv	cnv	NOUN
fnp-5842	320	21	plots	plot	NOUN
fnp-5842	320	22	from	from	ADP
fnp-5842	320	23	big	big	ADJ
fnp-5842	320	24	datasets	dataset	NOUN
fnp-5842	320	25	.	.	PUNCT
fnp-5842	321	1	p26	p26	NOUN
fnp-5842	321	2	free	free	ADJ
fnp-5842	321	3	neuropathol	neuropathol	NOUN
fnp-5842	321	4	5:19:39	5:19:39	NUM
fnp-5842	321	5	rapid	rapid	ADJ
fnp-5842	321	6	slice	slice	NOUN
fnp-5842	321	7	-	-	PUNCT
fnp-5842	321	8	free	free	ADJ
fnp-5842	321	9	intraoperative	intraoperative	ADJ
fnp-5842	321	10	histology	histology	NOUN
fnp-5842	321	11	in	in	ADP
fnp-5842	321	12	neurooncology	neurooncology	NOUN
fnp-5842	321	13	using	use	VERB
fnp-5842	321	14	multiphoton	multiphoton	NOUN
fnp-5842	321	15	microscopy	microscopy	NOUN
fnp-5842	321	16	–	–	PUNCT
fnp-5842	321	17	first	first	ADJ
fnp-5842	321	18	study	study	NOUN
fnp-5842	321	19	results	result	VERB
fnp-5842	321	20	jessica	jessica	PROPN
fnp-5842	321	21	kren1	kren1	PROPN
fnp-5842	321	22	,	,	PUNCT
fnp-5842	321	23	jan	jan	PROPN
fnp-5842	321	24	philip	philip	PROPN
fnp-5842	321	25	kolb2	kolb2	PROPN
fnp-5842	321	26	,	,	PUNCT
fnp-5842	321	27	matthias	matthias	PROPN
fnp-5842	321	28	strauch2	strauch2	PROPN
fnp-5842	321	29	,	,	PUNCT
fnp-5842	321	30	niloofar	niloofar	ADJ
fnp-5842	321	31	khosravi2	khosravi2	PROPN
fnp-5842	321	32	,	,	PUNCT
fnp-5842	321	33	alvaro	alvaro	PROPN
fnp-5842	321	34	vega	vega	PROPN
fnp-5842	321	35	perez2	perez2	PROPN
fnp-5842	321	36	,	,	PUNCT
fnp-5842	321	37	matteo	matteo	PROPN
fnp-5842	321	38	m.	m.	PROPN
fnp-5842	321	39	bonsanto1	bonsanto1	PROPN
fnp-5842	321	40	,	,	PUNCT
fnp-5842	321	41	julia	julia	PROPN
fnp-5842	321	42	e.	e.	PROPN
fnp-5842	321	43	neumann3,4	neumann3,4	PROPN
fnp-5842	321	44	1	1	NUM
fnp-5842	321	45	university	university	NOUN
fnp-5842	321	46	hospital	hospital	NOUN
fnp-5842	321	47	schleswig	schleswig	PROPN
fnp-5842	321	48	-	-	PUNCT
fnp-5842	321	49	holstein	holstein	PROPN
fnp-5842	321	50	,	,	PUNCT
fnp-5842	321	51	lubeck	lubeck	PROPN
fnp-5842	321	52	clinic	clinic	NOUN
fnp-5842	321	53	for	for	ADP
fnp-5842	321	54	neurosurgery	neurosurgery	NOUN
fnp-5842	321	55	,	,	PUNCT
fnp-5842	321	56	lübeck	lübeck	PROPN
fnp-5842	321	57	,	,	PUNCT
fnp-5842	321	58	germany	germany	PROPN
fnp-5842	321	59	2	2	NUM
fnp-5842	321	60	histolution	histolution	NOUN
fnp-5842	321	61	gmbh	gmbh	NOUN
fnp-5842	321	62	,	,	PUNCT
fnp-5842	321	63	lübeck	lübeck	PROPN
fnp-5842	321	64	,	,	PUNCT
fnp-5842	321	65	germany	germany	PROPN
fnp-5842	321	66	3	3	NUM
fnp-5842	321	67	institute	institute	PROPN
fnp-5842	321	68	for	for	ADP
fnp-5842	321	69	neuropathology	neuropathology	NOUN
fnp-5842	321	70	,	,	PUNCT
fnp-5842	321	71	university	university	NOUN
fnp-5842	321	72	hospital	hospital	NOUN
fnp-5842	321	73	hamburg	hamburg	PROPN
fnp-5842	321	74	-	-	PUNCT
fnp-5842	321	75	eppendorf	eppendorf	PROPN
fnp-5842	321	76	,	,	PUNCT
fnp-5842	321	77	hamburg	hamburg	PROPN
fnp-5842	321	78	,	,	PUNCT
fnp-5842	321	79	germany	germany	PROPN
fnp-5842	321	80	4	4	NUM
fnp-5842	321	81	center	center	NOUN
fnp-5842	321	82	for	for	ADP
fnp-5842	321	83	molecular	molecular	ADJ
fnp-5842	321	84	neurobiology	neurobiology	NOUN
fnp-5842	321	85	hamburg	hamburg	PROPN
fnp-5842	321	86	(	(	PUNCT
fnp-5842	321	87	zmnh	zmnh	PROPN
fnp-5842	321	88	)	)	PUNCT
fnp-5842	321	89	,	,	PUNCT
fnp-5842	321	90	university	university	NOUN
fnp-5842	321	91	hospital	hospital	NOUN
fnp-5842	321	92	hamburg	hamburg	PROPN
fnp-5842	321	93	-	-	PUNCT
fnp-5842	321	94	eppendorf	eppendorf	PROPN
fnp-5842	321	95	,	,	PUNCT
fnp-5842	321	96	hamburg	hamburg	PROPN
fnp-5842	321	97	,	,	PUNCT
fnp-5842	321	98	germany	germany	PROPN
fnp-5842	321	99	multiphoton	multiphoton	PROPN
fnp-5842	321	100	microscopy	microscopy	PROPN
fnp-5842	321	101	(	(	PUNCT
fnp-5842	321	102	mpm	mpm	NOUN
fnp-5842	321	103	)	)	PUNCT
fnp-5842	321	104	enables	enable	VERB
fnp-5842	321	105	histological	histological	ADJ
fnp-5842	321	106	examination	examination	NOUN
fnp-5842	321	107	of	of	ADP
fnp-5842	321	108	tissue	tissue	NOUN
fnp-5842	321	109	samples	sample	NOUN
fnp-5842	321	110	without	without	ADP
fnp-5842	321	111	the	the	DET
fnp-5842	321	112	prior	prior	ADJ
fnp-5842	321	113	production	production	NOUN
fnp-5842	321	114	of	of	ADP
fnp-5842	321	115	thin	thin	ADJ
fnp-5842	321	116	sections	section	NOUN
fnp-5842	321	117	using	use	VERB
fnp-5842	321	118	paraffin	paraffin	NOUN
fnp-5842	321	119	or	or	CCONJ
fnp-5842	321	120	frozen	frozen	ADJ
fnp-5842	321	121	preparation	preparation	NOUN
fnp-5842	321	122	.	.	PUNCT
fnp-5842	322	1	it	it	PRON
fnp-5842	322	2	can	can	AUX
fnp-5842	322	3	be	be	AUX
fnp-5842	322	4	applied	apply	VERB
fnp-5842	322	5	in	in	ADP
fnp-5842	322	6	the	the	DET
fnp-5842	322	7	operating	operating	NOUN
fnp-5842	322	8	room	room	NOUN
fnp-5842	322	9	(	(	PUNCT
fnp-5842	322	10	or	or	CCONJ
fnp-5842	322	11	)	)	PUNCT
fnp-5842	322	12	with	with	ADP
fnp-5842	322	13	less	less	ADJ
fnp-5842	322	14	effort	effort	NOUN
fnp-5842	322	15	and	and	CCONJ
fnp-5842	322	16	in	in	ADP
fnp-5842	322	17	just	just	ADV
fnp-5842	322	18	a	a	DET
fnp-5842	322	19	few	few	ADJ
fnp-5842	322	20	minutes	minute	NOUN
fnp-5842	322	21	.	.	PUNCT
fnp-5842	323	1	in	in	ADP
fnp-5842	323	2	a	a	DET
fnp-5842	323	3	proof	proof	NOUN
fnp-5842	323	4	of	of	ADP
fnp-5842	323	5	concept	concept	NOUN
fnp-5842	323	6	study	study	NOUN
fnp-5842	323	7	,	,	PUNCT
fnp-5842	323	8	we	we	PRON
fnp-5842	323	9	evaluated	evaluate	VERB
fnp-5842	323	10	mpm	mpm	NOUN
fnp-5842	323	11	on	on	ADP
fnp-5842	323	12	neurosurgical	neurosurgical	ADJ
fnp-5842	323	13	tumor	tumor	NOUN
fnp-5842	323	14	samples	sample	NOUN
fnp-5842	323	15	and	and	CCONJ
fnp-5842	323	16	compared	compare	VERB
fnp-5842	323	17	the	the	DET
fnp-5842	323	18	diagnostic	diagnostic	ADJ
fnp-5842	323	19	results	result	NOUN
fnp-5842	323	20	to	to	ADP
fnp-5842	323	21	the	the	DET
fnp-5842	323	22	routine	routine	ADJ
fnp-5842	323	23	histology	histology	NOUN
fnp-5842	323	24	.	.	PUNCT
fnp-5842	324	1	mpm	mpm	PROPN
fnp-5842	324	2	uses	use	VERB
fnp-5842	324	3	a	a	DET
fnp-5842	324	4	laser	laser	NOUN
fnp-5842	324	5	to	to	PART
fnp-5842	324	6	create	create	VERB
fnp-5842	324	7	non	non	ADJ
fnp-5842	324	8	-	-	ADJ
fnp-5842	324	9	linear	linear	ADJ
fnp-5842	324	10	optical	optical	ADJ
fnp-5842	324	11	effects	effect	NOUN
fnp-5842	324	12	that	that	PRON
fnp-5842	324	13	allow	allow	VERB
fnp-5842	324	14	tissue	tissue	NOUN
fnp-5842	324	15	blocks	block	NOUN
fnp-5842	324	16	to	to	PART
fnp-5842	324	17	be	be	AUX
fnp-5842	324	18	scanned	scan	VERB
fnp-5842	324	19	at	at	ADP
fnp-5842	324	20	adjustable	adjustable	ADJ
fnp-5842	324	21	depths	depth	NOUN
fnp-5842	324	22	.	.	PUNCT
fnp-5842	325	1	after	after	ADP
fnp-5842	325	2	a	a	DET
fnp-5842	325	3	2:30	2:30	NUM
fnp-5842	325	4	mins	min	NOUN
fnp-5842	325	5	long	long	ADJ
fnp-5842	325	6	staining	stain	VERB
fnp-5842	325	7	process	process	NOUN
fnp-5842	325	8	the	the	DET
fnp-5842	325	9	mpm	mpm	NOUN
fnp-5842	325	10	scanned	scan	VERB
fnp-5842	325	11	the	the	DET
fnp-5842	325	12	tissue	tissue	NOUN
fnp-5842	325	13	at	at	ADP
fnp-5842	325	14	a	a	DET
fnp-5842	325	15	speed	speed	NOUN
fnp-5842	325	16	of	of	ADP
fnp-5842	325	17	4	4	NUM
fnp-5842	325	18	 	 	SPACE
fnp-5842	325	19	min	min	NOUN
fnp-5842	325	20	/	/	SYM
fnp-5842	325	21	cm²	cm²	PROPN
fnp-5842	325	22	,	,	PUNCT
fnp-5842	325	23	with	with	ADP
fnp-5842	325	24	the	the	DET
fnp-5842	325	25	potential	potential	NOUN
fnp-5842	325	26	for	for	ADP
fnp-5842	325	27	further	further	ADJ
fnp-5842	325	28	acceleration	acceleration	NOUN
fnp-5842	325	29	to	to	ADP
fnp-5842	325	30	30	30	NUM
fnp-5842	325	31	 	 	SPACE
fnp-5842	325	32	s	s	PART
fnp-5842	325	33	/	/	SYM
fnp-5842	325	34	cm²	cm²	PROPN
fnp-5842	325	35	.	.	PUNCT
fnp-5842	326	1	the	the	DET
fnp-5842	326	2	results	result	NOUN
fnp-5842	326	3	are	be	AUX
fnp-5842	326	4	digital	digital	ADJ
fnp-5842	326	5	images	image	NOUN
fnp-5842	326	6	with	with	ADP
fnp-5842	326	7	high	high	ADJ
fnp-5842	326	8	similarity	similarity	NOUN
fnp-5842	326	9	to	to	ADP
fnp-5842	326	10	standard	standard	ADJ
fnp-5842	326	11	h&e	h&e	PROPN
fnp-5842	326	12	-	-	PUNCT
fnp-5842	326	13	stained	stain	VERB
fnp-5842	326	14	slides	slide	NOUN
fnp-5842	326	15	.	.	PUNCT
fnp-5842	327	1	12	12	NUM
fnp-5842	327	2	tissue	tissue	NOUN
fnp-5842	327	3	samples	sample	NOUN
fnp-5842	327	4	were	be	AUX
fnp-5842	327	5	collected	collect	VERB
fnp-5842	327	6	at	at	ADP
fnp-5842	327	7	the	the	DET
fnp-5842	327	8	clinic	clinic	NOUN
fnp-5842	327	9	for	for	ADP
fnp-5842	327	10	neurosurgery	neurosurgery	NOUN
fnp-5842	327	11	at	at	ADP
fnp-5842	327	12	uksh	uksh	PROPN
fnp-5842	327	13	lübeck	lübeck	PROPN
fnp-5842	327	14	.	.	PUNCT
fnp-5842	328	1	the	the	DET
fnp-5842	328	2	digital	digital	ADJ
fnp-5842	328	3	images	image	NOUN
fnp-5842	328	4	were	be	AUX
fnp-5842	328	5	evaluated	evaluate	VERB
fnp-5842	328	6	in	in	ADP
fnp-5842	328	7	a	a	DET
fnp-5842	328	8	blinded	blind	VERB
fnp-5842	328	9	manner	manner	NOUN
fnp-5842	328	10	by	by	ADP
fnp-5842	328	11	a	a	DET
fnp-5842	328	12	board	board	NOUN
fnp-5842	328	13	-	-	PUNCT
fnp-5842	328	14	certified	certify	VERB
fnp-5842	328	15	neuropathologist	neuropathologist	NOUN
fnp-5842	328	16	with	with	ADP
fnp-5842	328	17	no	no	DET
fnp-5842	328	18	prior	prior	ADJ
fnp-5842	328	19	training	training	NOUN
fnp-5842	328	20	in	in	ADP
fnp-5842	328	21	mpm	mpm	NOUN
fnp-5842	328	22	image	image	NOUN
fnp-5842	328	23	diagnosis	diagnosis	NOUN
fnp-5842	328	24	.	.	PUNCT
fnp-5842	329	1	only	only	ADV
fnp-5842	329	2	minimal	minimal	ADJ
fnp-5842	329	3	clinical	clinical	ADJ
fnp-5842	329	4	input	input	NOUN
fnp-5842	329	5	data	datum	NOUN
fnp-5842	329	6	was	be	AUX
fnp-5842	329	7	provided	provide	VERB
fnp-5842	329	8	(	(	PUNCT
fnp-5842	329	9	patient	patient	NOUN
fnp-5842	329	10	's	's	PART
fnp-5842	329	11	age	age	NOUN
fnp-5842	329	12	,	,	PUNCT
fnp-5842	329	13	sex	sex	NOUN
fnp-5842	329	14	,	,	PUNCT
fnp-5842	329	15	and	and	CCONJ
fnp-5842	329	16	sample	sample	NOUN
fnp-5842	329	17	localization	localization	NOUN
fnp-5842	329	18	)	)	PUNCT
fnp-5842	329	19	.	.	PUNCT
fnp-5842	330	1	in	in	ADP
fnp-5842	330	2	11	11	NUM
fnp-5842	330	3	of	of	ADP
fnp-5842	330	4	the	the	DET
fnp-5842	330	5	12	12	NUM
fnp-5842	330	6	cases	case	NOUN
fnp-5842	330	7	the	the	DET
fnp-5842	330	8	diagnosis	diagnosis	NOUN
fnp-5842	330	9	was	be	AUX
fnp-5842	330	10	consistent	consistent	ADJ
fnp-5842	330	11	with	with	ADP
fnp-5842	330	12	the	the	DET
fnp-5842	330	13	result	result	NOUN
fnp-5842	330	14	of	of	ADP
fnp-5842	330	15	the	the	DET
fnp-5842	330	16	routine	routine	ADJ
fnp-5842	330	17	analysis	analysis	NOUN
fnp-5842	330	18	.	.	PUNCT
fnp-5842	331	1	tissue	tissue	NOUN
fnp-5842	331	2	histomorphology	histomorphology	NOUN
fnp-5842	331	3	assessment	assessment	NOUN
fnp-5842	331	4	revealed	reveal	VERB
fnp-5842	331	5	a	a	DET
fnp-5842	331	6	good	good	ADJ
fnp-5842	331	7	assessability	assessability	NOUN
fnp-5842	331	8	of	of	ADP
fnp-5842	331	9	the	the	DET
fnp-5842	331	10	cell	cell	NOUN
fnp-5842	331	11	morphology	morphology	NOUN
fnp-5842	331	12	and	and	CCONJ
fnp-5842	331	13	tissue	tissue	NOUN
fnp-5842	331	14	texture	texture	NOUN
fnp-5842	331	15	compared	compare	VERB
fnp-5842	331	16	to	to	ADP
fnp-5842	331	17	standard	standard	ADJ
fnp-5842	331	18	slides	slide	NOUN
fnp-5842	331	19	.	.	PUNCT
fnp-5842	332	1	the	the	DET
fnp-5842	332	2	initial	initial	ADJ
fnp-5842	332	3	results	result	NOUN
fnp-5842	332	4	show	show	VERB
fnp-5842	332	5	that	that	SCONJ
fnp-5842	332	6	the	the	DET
fnp-5842	332	7	mpm	mpm	NOUN
fnp-5842	332	8	is	be	AUX
fnp-5842	332	9	a	a	DET
fnp-5842	332	10	valuable	valuable	ADJ
fnp-5842	332	11	tool	tool	NOUN
fnp-5842	332	12	for	for	ADP
fnp-5842	332	13	accelerating	accelerate	VERB
fnp-5842	332	14	and	and	CCONJ
fnp-5842	332	15	simplifying	simplify	VERB
fnp-5842	332	16	intraoperative	intraoperative	ADJ
fnp-5842	332	17	histological	histological	ADJ
fnp-5842	332	18	examinations	examination	NOUN
fnp-5842	332	19	in	in	ADP
fnp-5842	332	20	neurosurgery	neurosurgery	NOUN
fnp-5842	332	21	without	without	ADP
fnp-5842	332	22	the	the	DET
fnp-5842	332	23	need	need	NOUN
fnp-5842	332	24	for	for	ADP
fnp-5842	332	25	device	device	NOUN
fnp-5842	332	26	-	-	PUNCT
fnp-5842	332	27	specific	specific	ADJ
fnp-5842	332	28	training	training	NOUN
fnp-5842	332	29	of	of	ADP
fnp-5842	332	30	the	the	DET
fnp-5842	332	31	neuropathologist	neuropathologist	NOUN
fnp-5842	332	32	.	.	PUNCT
fnp-5842	333	1	in	in	ADP
fnp-5842	333	2	ongoing	ongoing	ADJ
fnp-5842	333	3	research	research	NOUN
fnp-5842	333	4	,	,	PUNCT
fnp-5842	333	5	we	we	PRON
fnp-5842	333	6	will	will	AUX
fnp-5842	333	7	further	far	ADV
fnp-5842	333	8	optimize	optimize	VERB
fnp-5842	333	9	the	the	DET
fnp-5842	333	10	technical	technical	ADJ
fnp-5842	333	11	settings	setting	NOUN
fnp-5842	333	12	and	and	CCONJ
fnp-5842	333	13	increase	increase	VERB
fnp-5842	333	14	the	the	DET
fnp-5842	333	15	cohort	cohort	NOUN
fnp-5842	333	16	size	size	NOUN
fnp-5842	333	17	to	to	PART
fnp-5842	333	18	validate	validate	VERB
fnp-5842	333	19	a	a	DET
fnp-5842	333	20	broad	broad	ADJ
fnp-5842	333	21	applicability	applicability	NOUN
fnp-5842	333	22	in	in	ADP
fnp-5842	333	23	neurooncology	neurooncology	NOUN
fnp-5842	333	24	.	.	PUNCT
fnp-5842	334	1	p27	p27	PROPN
fnp-5842	334	2	free	free	ADJ
fnp-5842	334	3	neuropathol	neuropathol	NOUN
fnp-5842	334	4	5:19:40	5:19:40	NUM
fnp-5842	334	5	predicting	predict	VERB
fnp-5842	334	6	epigenetic	epigenetic	ADJ
fnp-5842	334	7	ependymoma	ependymoma	NOUN
fnp-5842	334	8	types	type	NOUN
fnp-5842	334	9	from	from	ADP
fnp-5842	334	10	histological	histological	ADJ
fnp-5842	334	11	whole	whole	ADJ
fnp-5842	334	12	-	-	PUNCT
fnp-5842	334	13	slide	slide	NOUN
fnp-5842	334	14	images	image	NOUN
fnp-5842	334	15	using	use	VERB
fnp-5842	334	16	neural	neural	ADJ
fnp-5842	334	17	networks	network	NOUN
fnp-5842	334	18	maximillian	maximillian	PROPN
fnp-5842	334	19	middelkamp1	middelkamp1	PROPN
fnp-5842	334	20	,	,	PUNCT
fnp-5842	334	21	*	*	PROPN
fnp-5842	334	22	,	,	PUNCT
fnp-5842	334	23	yannis	yannis	PROPN
fnp-5842	334	24	schumann2	schumann2	PROPN
fnp-5842	334	25	,	,	PUNCT
fnp-5842	334	26	*	*	PUNCT
fnp-5842	334	27	,	,	PUNCT
fnp-5842	334	28	matthias	matthias	PROPN
fnp-5842	334	29	dottermusch3,4	dottermusch3,4	PROPN
fnp-5842	334	30	,	,	PUNCT
fnp-5842	334	31	leonille	leonille	PROPN
fnp-5842	334	32	schweizer5,6,7	schweizer5,6,7	PROPN
fnp-5842	334	33	,	,	PUNCT
fnp-5842	334	34	maja	maja	PROPN
fnp-5842	334	35	krech8	krech8	PROPN
fnp-5842	334	36	,	,	PUNCT
fnp-5842	334	37	tasja	tasja	PROPN
fnp-5842	334	38	lempertz2,3	lempertz2,3	PROPN
fnp-5842	334	39	,	,	PUNCT
fnp-5842	334	40	jens	jens	PROPN
fnp-5842	334	41	gempt1	gempt1	PROPN
fnp-5842	334	42	,	,	PUNCT
fnp-5842	334	43	ulrich	ulrich	PROPN
fnp-5842	334	44	schüller3,9,10	schüller3,9,10	PROPN
fnp-5842	334	45	,	,	PUNCT
fnp-5842	334	46	philipp	philipp	PROPN
fnp-5842	334	47	neumann2	neumann2	PROPN
fnp-5842	334	48	,	,	PUNCT
fnp-5842	334	49	julia	julia	PROPN
fnp-5842	334	50	e.	e.	PROPN
fnp-5842	334	51	neumann3,4	neumann3,4	PROPN
fnp-5842	334	52	1	1	NUM
fnp-5842	334	53	department	department	NOUN
fnp-5842	334	54	of	of	ADP
fnp-5842	334	55	neurosurgery	neurosurgery	NOUN
fnp-5842	334	56	,	,	PUNCT
fnp-5842	334	57	university	university	NOUN
fnp-5842	334	58	medical	medical	ADJ
fnp-5842	334	59	center	center	PROPN
fnp-5842	334	60	hamburg	hamburg	PROPN
fnp-5842	334	61	-	-	PUNCT
fnp-5842	334	62	eppendorf	eppendorf	PROPN
fnp-5842	334	63	,	,	PUNCT
fnp-5842	334	64	20246	20246	NUM
fnp-5842	334	65	hamburg	hamburg	PROPN
fnp-5842	334	66	,	,	PUNCT
fnp-5842	334	67	germany	germany	PROPN
fnp-5842	334	68	2	2	NUM
fnp-5842	334	69	chair	chair	NOUN
fnp-5842	334	70	for	for	ADP
fnp-5842	334	71	high	high	ADJ
fnp-5842	334	72	performance	performance	NOUN
fnp-5842	334	73	computing	computing	NOUN
fnp-5842	334	74	,	,	PUNCT
fnp-5842	334	75	helmut	helmut	NOUN
fnp-5842	334	76	-	-	PUNCT
fnp-5842	334	77	schmidt	schmidt	NOUN
fnp-5842	334	78	-	-	PUNCT
fnp-5842	334	79	university	university	NOUN
fnp-5842	334	80	/	/	SYM
fnp-5842	334	81	university	university	NOUN
fnp-5842	334	82	of	of	ADP
fnp-5842	334	83	the	the	DET
fnp-5842	334	84	federal	federal	ADJ
fnp-5842	334	85	armed	armed	ADJ
fnp-5842	334	86	forces	force	NOUN
fnp-5842	334	87	hamburg	hamburg	PROPN
fnp-5842	334	88	,	,	PUNCT
fnp-5842	334	89	holstenhofweg	holstenhofweg	NOUN
fnp-5842	334	90	85	85	NUM
fnp-5842	334	91	,	,	PUNCT
fnp-5842	334	92	22043	22043	NUM
fnp-5842	334	93	hamburg	hamburg	PROPN
fnp-5842	334	94	,	,	PUNCT
fnp-5842	334	95	germany	germany	PROPN
fnp-5842	334	96	3	3	NUM
fnp-5842	334	97	institute	institute	PROPN
fnp-5842	334	98	for	for	ADP
fnp-5842	334	99	neuropathology	neuropathology	NOUN
fnp-5842	334	100	,	,	PUNCT
fnp-5842	334	101	university	university	NOUN
fnp-5842	334	102	medical	medical	ADJ
fnp-5842	334	103	center	center	PROPN
fnp-5842	334	104	hamburg	hamburg	PROPN
fnp-5842	334	105	-	-	PUNCT
fnp-5842	334	106	eppendorf	eppendorf	PROPN
fnp-5842	334	107	,	,	PUNCT
fnp-5842	334	108	martinistrasse	martinistrasse	VERB
fnp-5842	334	109	52	52	NUM
fnp-5842	334	110	20246	20246	NUM
fnp-5842	334	111	hamburg	hamburg	PROPN
fnp-5842	334	112	,	,	PUNCT
fnp-5842	334	113	germany	germany	PROPN
fnp-5842	334	114	4	4	NUM
fnp-5842	334	115	center	center	NOUN
fnp-5842	334	116	for	for	ADP
fnp-5842	334	117	molecular	molecular	ADJ
fnp-5842	334	118	neurobiology	neurobiology	NOUN
fnp-5842	334	119	hamburg	hamburg	PROPN
fnp-5842	334	120	,	,	PUNCT
fnp-5842	334	121	university	university	NOUN
fnp-5842	334	122	medical	medical	ADJ
fnp-5842	334	123	center	center	PROPN
fnp-5842	334	124	hamburg	hamburg	PROPN
fnp-5842	334	125	-	-	PUNCT
fnp-5842	334	126	eppendorf	eppendorf	PROPN
fnp-5842	334	127	,	,	PUNCT
fnp-5842	334	128	falkenried	falkenrie	VERB
fnp-5842	334	129	94	94	NUM
fnp-5842	334	130	,	,	PUNCT
fnp-5842	334	131	20251	20251	NUM
fnp-5842	334	132	hamburg	hamburg	PROPN
fnp-5842	334	133	,	,	PUNCT
fnp-5842	334	134	germany	germany	PROPN
fnp-5842	334	135	5	5	NUM
fnp-5842	334	136	institute	institute	PROPN
fnp-5842	334	137	of	of	ADP
fnp-5842	334	138	neurology	neurology	NOUN
fnp-5842	334	139	(	(	PUNCT
fnp-5842	334	140	edinger	edinger	PROPN
fnp-5842	334	141	institute	institute	PROPN
fnp-5842	334	142	)	)	PUNCT
fnp-5842	334	143	,	,	PUNCT
fnp-5842	334	144	university	university	NOUN
fnp-5842	334	145	hospital	hospital	NOUN
fnp-5842	334	146	frankfurt	frankfurt	PROPN
fnp-5842	334	147	,	,	PUNCT
fnp-5842	334	148	theodor	theodor	NOUN
fnp-5842	334	149	-	-	PUNCT
fnp-5842	334	150	stern	stern	ADJ
fnp-5842	334	151	-	-	PUNCT
fnp-5842	334	152	kai	kai	NOUN
fnp-5842	334	153	7	7	NUM
fnp-5842	334	154	,	,	PUNCT
fnp-5842	334	155	60590	60590	NUM
fnp-5842	334	156	frankfurt	frankfurt	NOUN
fnp-5842	334	157	am	be	AUX
fnp-5842	334	158	main	main	ADJ
fnp-5842	334	159	,	,	PUNCT
fnp-5842	334	160	germany	germany	NOUN
fnp-5842	334	161	6	6	NUM
fnp-5842	334	162	german	german	ADJ
fnp-5842	334	163	cancer	cancer	NOUN
fnp-5842	334	164	consortium	consortium	NOUN
fnp-5842	334	165	(	(	PUNCT
fnp-5842	334	166	dktk	dktk	NOUN
fnp-5842	334	167	)	)	PUNCT
fnp-5842	334	168	,	,	PUNCT
fnp-5842	334	169	partner	partner	NOUN
fnp-5842	334	170	site	site	NOUN
fnp-5842	334	171	frankfurt	frankfurt	PROPN
fnp-5842	334	172	/	/	SYM
fnp-5842	334	173	mainz	mainz	PROPN
fnp-5842	334	174	,	,	PUNCT
fnp-5842	334	175	german	german	ADJ
fnp-5842	334	176	cancer	cancer	NOUN
fnp-5842	334	177	research	research	NOUN
fnp-5842	334	178	center	center	NOUN
fnp-5842	334	179	(	(	PUNCT
fnp-5842	334	180	dkfz	dkfz	PROPN
fnp-5842	334	181	)	)	PUNCT
fnp-5842	334	182	,	,	PUNCT
fnp-5842	334	183	heidelberg	heidelberg	PROPN
fnp-5842	334	184	,	,	PUNCT
fnp-5842	334	185	germany	germany	PROPN
fnp-5842	334	186	7	7	NUM
fnp-5842	334	187	frankfurt	frankfurt	PROPN
fnp-5842	334	188	cancer	cancer	PROPN
fnp-5842	334	189	institute	institute	PROPN
fnp-5842	334	190	(	(	PUNCT
fnp-5842	334	191	fci	fci	PROPN
fnp-5842	334	192	)	)	PUNCT
fnp-5842	334	193	,	,	PUNCT
fnp-5842	334	194	paul	paul	PROPN
fnp-5842	334	195	-	-	PUNCT
fnp-5842	334	196	ehrlich	ehrlich	NOUN
fnp-5842	334	197	-	-	PUNCT
fnp-5842	334	198	str	str	NOUN
fnp-5842	334	199	.	.	PUNCT
fnp-5842	335	1	42–44	42–44	NUM
fnp-5842	335	2	,	,	PUNCT
fnp-5842	335	3	60596	60596	NUM
fnp-5842	335	4	frankfurt	frankfurt	PROPN
fnp-5842	335	5	am	be	AUX
fnp-5842	335	6	main	main	ADJ
fnp-5842	335	7	,	,	PUNCT
fnp-5842	335	8	germany	germany	PROPN
fnp-5842	335	9	8	8	NUM
fnp-5842	335	10	institute	institute	PROPN
fnp-5842	335	11	for	for	ADP
fnp-5842	335	12	neuropathology	neuropathology	NOUN
fnp-5842	335	13	,	,	PUNCT
fnp-5842	335	14	charité	charité	PROPN
fnp-5842	335	15	berlin	berlin	PROPN
fnp-5842	335	16	,	,	PUNCT
fnp-5842	335	17	charitéplatz	charitéplatz	PROPN
fnp-5842	335	18	1	1	NUM
fnp-5842	335	19	,	,	PUNCT
fnp-5842	335	20	virchowweg	virchowweg	VERB
fnp-5842	335	21	15	15	NUM
fnp-5842	335	22	,	,	PUNCT
fnp-5842	335	23	10117	10117	NUM
fnp-5842	335	24	berlin	berlin	PROPN
fnp-5842	335	25	,	,	PUNCT
fnp-5842	335	26	germany	germany	PROPN
fnp-5842	335	27	9	9	NUM
fnp-5842	335	28	research	research	PROPN
fnp-5842	335	29	institute	institute	NOUN
fnp-5842	335	30	children	child	NOUN
fnp-5842	335	31	’s	’s	PART
fnp-5842	335	32	cancer	cancer	NOUN
fnp-5842	335	33	center	center	PROPN
fnp-5842	335	34	hamburg	hamburg	PROPN
fnp-5842	335	35	,	,	PUNCT
fnp-5842	335	36	uke	uke	PROPN
fnp-5842	335	37	,	,	PUNCT
fnp-5842	335	38	martinistrasse	martinistrasse	VERB
fnp-5842	335	39	52	52	NUM
fnp-5842	335	40	,	,	PUNCT
fnp-5842	335	41	20246	20246	NUM
fnp-5842	335	42	hamburg	hamburg	PROPN
fnp-5842	335	43	,	,	PUNCT
fnp-5842	335	44	germany	germany	PROPN
fnp-5842	335	45	10	10	NUM
fnp-5842	335	46	department	department	PROPN
fnp-5842	335	47	of	of	ADP
fnp-5842	335	48	pediatric	pediatric	ADJ
fnp-5842	335	49	hematology	hematology	NOUN
fnp-5842	335	50	and	and	CCONJ
fnp-5842	335	51	oncology	oncology	NOUN
fnp-5842	335	52	,	,	PUNCT
fnp-5842	335	53	uke	uke	PROPN
fnp-5842	335	54	,	,	PUNCT
fnp-5842	335	55	martinistrasse	martinistrasse	VERB
fnp-5842	335	56	52	52	NUM
fnp-5842	335	57	,	,	PUNCT
fnp-5842	335	58	20246	20246	NUM
fnp-5842	335	59	hamburg	hamburg	PROPN
fnp-5842	335	60	,	,	PUNCT
fnp-5842	335	61	germany	germany	PROPN
fnp-5842	335	62	*	*	PUNCT
fnp-5842	336	1	authors	author	NOUN
fnp-5842	336	2	contributed	contribute	VERB
fnp-5842	336	3	equally	equally	ADV
fnp-5842	336	4	keywords	keyword	NOUN
fnp-5842	336	5	:	:	PUNCT
fnp-5842	336	6	neuropathology	neuropathology	NOUN
fnp-5842	336	7	,	,	PUNCT
fnp-5842	336	8	cancer	cancer	NOUN
fnp-5842	336	9	,	,	PUNCT
fnp-5842	336	10	multiple	multiple	ADJ
fnp-5842	336	11	instance	instance	NOUN
fnp-5842	336	12	learning	learning	NOUN
fnp-5842	336	13	,	,	PUNCT
fnp-5842	336	14	self	self	NOUN
fnp-5842	336	15	-	-	PUNCT
fnp-5842	336	16	supervised	supervise	VERB
fnp-5842	336	17	learning	learning	NOUN
fnp-5842	336	18	,	,	PUNCT
fnp-5842	336	19	attention	attention	NOUN
fnp-5842	336	20	ependymomas	ependymomas	PROPN
fnp-5842	336	21	are	be	AUX
fnp-5842	336	22	neuroepithelial	neuroepithelial	ADJ
fnp-5842	336	23	neoplasms	neoplasm	NOUN
fnp-5842	336	24	of	of	ADP
fnp-5842	336	25	the	the	DET
fnp-5842	336	26	central	central	ADJ
fnp-5842	336	27	nervous	nervous	ADJ
fnp-5842	336	28	system	system	NOUN
fnp-5842	336	29	and	and	CCONJ
fnp-5842	336	30	comprise	comprise	VERB
fnp-5842	336	31	(	(	PUNCT
fnp-5842	336	32	at	at	ADP
fnp-5842	336	33	least	least	ADJ
fnp-5842	336	34	)	)	PUNCT
fnp-5842	336	35	10	10	NUM
fnp-5842	336	36	main	main	ADJ
fnp-5842	336	37	clinically	clinically	ADV
fnp-5842	336	38	distinct	distinct	ADJ
fnp-5842	336	39	types	type	NOUN
fnp-5842	336	40	based	base	VERB
fnp-5842	336	41	on	on	ADP
fnp-5842	336	42	epigenetic	epigenetic	ADJ
fnp-5842	336	43	(	(	PUNCT
fnp-5842	336	44	dna	dna	NOUN
fnp-5842	336	45	methylation	methylation	NOUN
fnp-5842	336	46	)	)	PUNCT
fnp-5842	336	47	profiles	profile	NOUN
fnp-5842	336	48	.	.	PUNCT
fnp-5842	337	1	for	for	ADP
fnp-5842	337	2	their	their	PRON
fnp-5842	337	3	diagnosis	diagnosis	NOUN
fnp-5842	337	4	,	,	PUNCT
fnp-5842	337	5	the	the	DET
fnp-5842	337	6	current	current	ADJ
fnp-5842	337	7	standard	standard	ADJ
fnp-5842	337	8	practice	practice	NOUN
fnp-5842	337	9	is	be	AUX
fnp-5842	337	10	to	to	PART
fnp-5842	337	11	integrate	integrate	VERB
fnp-5842	337	12	time	time	NOUN
fnp-5842	337	13	consuming	consume	VERB
fnp-5842	337	14	epigenetic	epigenetic	ADJ
fnp-5842	337	15	analyses	analysis	NOUN
fnp-5842	337	16	with	with	ADP
fnp-5842	337	17	histological	histological	ADJ
fnp-5842	337	18	assessment	assessment	NOUN
fnp-5842	337	19	.	.	PUNCT
fnp-5842	338	1	we	we	PRON
fnp-5842	338	2	asked	ask	VERB
fnp-5842	338	3	whether	whether	SCONJ
fnp-5842	338	4	neural	neural	ADJ
fnp-5842	338	5	networks	network	NOUN
fnp-5842	338	6	can	can	AUX
fnp-5842	338	7	predict	predict	VERB
fnp-5842	338	8	the	the	DET
fnp-5842	338	9	dna	dna	PROPN
fnp-5842	338	10	methylation	methylation	NOUN
fnp-5842	338	11	class	class	NOUN
fnp-5842	338	12	of	of	ADP
fnp-5842	338	13	ependymoma	ependymoma	NOUN
fnp-5842	338	14	types	type	NOUN
fnp-5842	338	15	from	from	ADP
fnp-5842	338	16	hematoxylin	hematoxylin	NOUN
fnp-5842	338	17	and	and	CCONJ
fnp-5842	338	18	eosin	eosin	NOUN
fnp-5842	338	19	stained	stain	VERB
fnp-5842	338	20	whole	whole	ADJ
fnp-5842	338	21	-	-	PUNCT
fnp-5842	338	22	slide	slide	NOUN
fnp-5842	338	23	images	image	NOUN
fnp-5842	338	24	.	.	PUNCT
fnp-5842	339	1	using	use	VERB
fnp-5842	339	2	explainable	explainable	ADJ
fnp-5842	339	3	ai	ai	NOUN
fnp-5842	339	4	,	,	PUNCT
fnp-5842	339	5	we	we	PRON
fnp-5842	339	6	further	far	ADV
fnp-5842	339	7	aimed	aim	VERB
fnp-5842	339	8	to	to	PART
fnp-5842	339	9	prospectively	prospectively	ADV
fnp-5842	339	10	improve	improve	VERB
fnp-5842	339	11	the	the	DET
fnp-5842	339	12	consistency	consistency	NOUN
fnp-5842	339	13	of	of	ADP
fnp-5842	339	14	histology	histology	NOUN
fnp-5842	339	15	-	-	PUNCT
fnp-5842	339	16	based	base	VERB
fnp-5842	339	17	diagnoses	diagnosis	NOUN
fnp-5842	339	18	with	with	ADP
fnp-5842	339	19	dna	dna	PROPN
fnp-5842	339	20	methylation	methylation	NOUN
fnp-5842	339	21	profiling	profiling	NOUN
fnp-5842	339	22	by	by	ADP
fnp-5842	339	23	identifying	identify	VERB
fnp-5842	339	24	and	and	CCONJ
fnp-5842	339	25	quantifying	quantify	VERB
fnp-5842	339	26	distinct	distinct	ADJ
fnp-5842	339	27	morphological	morphological	ADJ
fnp-5842	339	28	patterns	pattern	NOUN
fnp-5842	339	29	of	of	ADP
fnp-5842	339	30	these	these	DET
fnp-5842	339	31	molecular	molecular	ADJ
fnp-5842	339	32	ependymoma	ependymoma	NOUN
fnp-5842	339	33	types	type	NOUN
fnp-5842	339	34	.	.	PUNCT
fnp-5842	340	1	we	we	PRON
fnp-5842	340	2	collected	collect	VERB
fnp-5842	340	3	sample	sample	NOUN
fnp-5842	340	4	-	-	PUNCT
fnp-5842	340	5	matched	match	VERB
fnp-5842	340	6	epigenetic	epigenetic	ADJ
fnp-5842	340	7	profiles	profile	NOUN
fnp-5842	340	8	and	and	CCONJ
fnp-5842	340	9	whole	whole	ADJ
fnp-5842	340	10	-	-	PUNCT
fnp-5842	340	11	slide	slide	NOUN
fnp-5842	340	12	images	image	NOUN
fnp-5842	340	13	(	(	PUNCT
fnp-5842	340	14	hematoxylinand	hematoxylinand	NOUN
fnp-5842	340	15	eosin	eosin	NOUN
fnp-5842	340	16	stain	stain	NOUN
fnp-5842	340	17	)	)	PUNCT
fnp-5842	340	18	of	of	ADP
fnp-5842	340	19	>	>	PUNCT
fnp-5842	340	20	 	 	SPACE
fnp-5842	340	21	500	500	NUM
fnp-5842	340	22	ependymomas	ependymoma	NOUN
fnp-5842	340	23	from	from	ADP
fnp-5842	340	24	different	different	ADJ
fnp-5842	340	25	anatomical	anatomical	ADJ
fnp-5842	340	26	compartments	compartment	NOUN
fnp-5842	340	27	.	.	PUNCT
fnp-5842	341	1	attention	attention	NOUN
fnp-5842	341	2	-	-	PUNCT
fnp-5842	341	3	based	base	VERB
fnp-5842	341	4	classification	classification	NOUN
fnp-5842	341	5	models	model	NOUN
fnp-5842	341	6	(	(	PUNCT
fnp-5842	341	7	clam	clam	PROPN
fnp-5842	341	8	)	)	PUNCT
fnp-5842	341	9	or	or	CCONJ
fnp-5842	341	10	multi	multi	ADJ
fnp-5842	341	11	-	-	ADJ
fnp-5842	341	12	grid	grid	ADJ
fnp-5842	341	13	vision	vision	NOUN
fnp-5842	341	14	transformers	transformer	NOUN
fnp-5842	341	15	(	(	PUNCT
fnp-5842	341	16	vits	vit	NOUN
fnp-5842	341	17	)	)	PUNCT
fnp-5842	341	18	were	be	AUX
fnp-5842	341	19	trained	train	VERB
fnp-5842	341	20	to	to	PART
fnp-5842	341	21	predict	predict	VERB
fnp-5842	341	22	the	the	DET
fnp-5842	341	23	epigenetic	epigenetic	ADJ
fnp-5842	341	24	ependymoma	ependymoma	NOUN
fnp-5842	341	25	types	type	NOUN
fnp-5842	341	26	from	from	ADP
fnp-5842	341	27	the	the	DET
fnp-5842	341	28	slide	slide	NOUN
fnp-5842	341	29	images	image	NOUN
fnp-5842	341	30	and	and	CCONJ
fnp-5842	341	31	the	the	DET
fnp-5842	341	32	models	model	NOUN
fnp-5842	341	33	were	be	AUX
fnp-5842	341	34	compared	compare	VERB
fnp-5842	341	35	the	the	DET
fnp-5842	341	36	results	result	NOUN
fnp-5842	341	37	from	from	ADP
fnp-5842	341	38	histological	histological	ADJ
fnp-5842	341	39	annotations	annotation	NOUN
fnp-5842	341	40	by	by	ADP
fnp-5842	341	41	neuropathologists	neuropathologist	NOUN
fnp-5842	341	42	for	for	ADP
fnp-5842	341	43	a	a	DET
fnp-5842	341	44	fraction	fraction	NOUN
fnp-5842	341	45	of	of	ADP
fnp-5842	341	46	cases	case	NOUN
fnp-5842	341	47	.	.	PUNCT
fnp-5842	342	1	our	our	PRON
fnp-5842	342	2	approach	approach	NOUN
fnp-5842	342	3	yielded	yield	VERB
fnp-5842	342	4	reliable	reliable	ADJ
fnp-5842	342	5	predictions	prediction	NOUN
fnp-5842	342	6	of	of	ADP
fnp-5842	342	7	the	the	DET
fnp-5842	342	8	epigenetic	epigenetic	ADJ
fnp-5842	342	9	types	type	NOUN
fnp-5842	342	10	based	base	VERB
fnp-5842	342	11	on	on	ADP
fnp-5842	342	12	histomorphological	histomorphological	ADJ
fnp-5842	342	13	data	datum	NOUN
fnp-5842	342	14	.	.	PUNCT
fnp-5842	343	1	self	self	NOUN
fnp-5842	343	2	-	-	PUNCT
fnp-5842	343	3	supervised	supervise	VERB
fnp-5842	343	4	encoder	encoder	NOUN
fnp-5842	343	5	training	training	NOUN
fnp-5842	343	6	was	be	AUX
fnp-5842	343	7	crucial	crucial	ADJ
fnp-5842	343	8	for	for	ADP
fnp-5842	343	9	classification	classification	NOUN
fnp-5842	343	10	performance	performance	NOUN
fnp-5842	343	11	.	.	PUNCT
fnp-5842	344	1	the	the	DET
fnp-5842	344	2	classifiers	classifier	NOUN
fnp-5842	344	3	improved	improve	VERB
fnp-5842	344	4	over	over	ADP
fnp-5842	344	5	board	board	NOUN
fnp-5842	344	6	-	-	PUNCT
fnp-5842	344	7	certified	certify	VERB
fnp-5842	344	8	neuropathologists	neuropathologist	NOUN
fnp-5842	344	9	and	and	CCONJ
fnp-5842	344	10	its	its	PRON
fnp-5842	344	11	attentions	attention	NOUN
fnp-5842	344	12	scores	score	NOUN
fnp-5842	344	13	were	be	AUX
fnp-5842	344	14	leveraged	leverage	VERB
fnp-5842	344	15	to	to	PART
fnp-5842	344	16	correlate	correlate	VERB
fnp-5842	344	17	epigenetic	epigenetic	ADJ
fnp-5842	344	18	and	and	CCONJ
fnp-5842	344	19	morphological	morphological	ADJ
fnp-5842	344	20	ependymoma	ependymoma	NOUN
fnp-5842	344	21	characteristics	characteristic	NOUN
fnp-5842	344	22	.	.	PUNCT
fnp-5842	345	1	image	image	NOUN
fnp-5842	345	2	normalization	normalization	NOUN
fnp-5842	345	3	and	and	CCONJ
fnp-5842	345	4	augmentation	augmentation	NOUN
fnp-5842	345	5	facilitated	facilitate	VERB
fnp-5842	345	6	domain	domain	NOUN
fnp-5842	345	7	adaptation	adaptation	NOUN
fnp-5842	345	8	towards	towards	ADP
fnp-5842	345	9	whole	whole	ADJ
fnp-5842	345	10	-	-	PUNCT
fnp-5842	345	11	slide	slide	NOUN
fnp-5842	345	12	images	image	NOUN
fnp-5842	345	13	from	from	ADP
fnp-5842	345	14	other	other	ADJ
fnp-5842	345	15	medical	medical	ADJ
fnp-5842	345	16	facilities	facility	NOUN
fnp-5842	345	17	and	and	CCONJ
fnp-5842	345	18	brightfield	brightfield	NOUN
fnp-5842	345	19	microscopy	microscopy	NOUN
fnp-5842	345	20	images	image	NOUN
fnp-5842	345	21	.	.	PUNCT
fnp-5842	346	1	we	we	PRON
fnp-5842	346	2	established	establish	VERB
fnp-5842	346	3	an	an	DET
fnp-5842	346	4	interpretable	interpretable	ADJ
fnp-5842	346	5	method	method	NOUN
fnp-5842	346	6	to	to	PART
fnp-5842	346	7	reliably	reliably	ADV
fnp-5842	346	8	predict	predict	VERB
fnp-5842	346	9	epigenetic	epigenetic	ADJ
fnp-5842	346	10	ependymoma	ependymoma	NOUN
fnp-5842	346	11	types	type	NOUN
fnp-5842	346	12	from	from	ADP
fnp-5842	346	13	histological	histological	ADJ
fnp-5842	346	14	whole	whole	ADJ
fnp-5842	346	15	-	-	PUNCT
fnp-5842	346	16	slide	slide	NOUN
fnp-5842	346	17	images	image	NOUN
fnp-5842	346	18	.	.	PUNCT
fnp-5842	347	1	our	our	PRON
fnp-5842	347	2	approach	approach	NOUN
fnp-5842	347	3	provides	provide	VERB
fnp-5842	347	4	a	a	DET
fnp-5842	347	5	fast	fast	ADJ
fnp-5842	347	6	and	and	CCONJ
fnp-5842	347	7	inexpensive	inexpensive	ADJ
fnp-5842	347	8	way	way	NOUN
fnp-5842	347	9	for	for	ADP
fnp-5842	347	10	first	first	ADJ
fnp-5842	347	11	assessment	assessment	NOUN
fnp-5842	347	12	of	of	ADP
fnp-5842	347	13	molecular	molecular	ADJ
fnp-5842	347	14	ependymoma	ependymoma	NOUN
fnp-5842	347	15	classification	classification	NOUN
fnp-5842	347	16	,	,	PUNCT
fnp-5842	347	17	provides	provide	VERB
fnp-5842	347	18	morphological	morphological	ADJ
fnp-5842	347	19	interpretability	interpretability	NOUN
fnp-5842	347	20	and	and	CCONJ
fnp-5842	347	21	may	may	AUX
fnp-5842	347	22	prospectively	prospectively	ADV
fnp-5842	347	23	enable	enable	VERB
fnp-5842	347	24	rapid	rapid	ADJ
fnp-5842	347	25	decisions	decision	NOUN
fnp-5842	347	26	on	on	ADP
fnp-5842	347	27	patient	patient	NOUN
fnp-5842	347	28	-	-	PUNCT
fnp-5842	347	29	specific	specific	ADJ
fnp-5842	347	30	treatment	treatment	NOUN
fnp-5842	347	31	in	in	ADP
fnp-5842	347	32	the	the	DET
fnp-5842	347	33	upcoming	upcoming	ADJ
fnp-5842	347	34	era	era	NOUN
fnp-5842	347	35	of	of	ADP
fnp-5842	347	36	digital	digital	ADJ
fnp-5842	347	37	pathology	pathology	NOUN
fnp-5842	347	38	.	.	PUNCT
fnp-5842	348	1	p28	p28	NOUN
fnp-5842	348	2	free	free	ADJ
fnp-5842	348	3	neuropathol	neuropathol	NOUN
fnp-5842	348	4	5:19:42	5:19:42	NUM
fnp-5842	348	5	established	establish	VERB
fnp-5842	348	6	in	in	ADP
fnp-5842	348	7	1902	1902	NUM
fnp-5842	348	8	:	:	PUNCT
fnp-5842	348	9	a	a	DET
fnp-5842	348	10	brief	brief	ADJ
fnp-5842	348	11	history	history	NOUN
fnp-5842	348	12	of	of	ADP
fnp-5842	348	13	the	the	DET
fnp-5842	348	14	institute	institute	PROPN
fnp-5842	348	15	of	of	ADP
fnp-5842	348	16	neurology	neurology	NOUN
fnp-5842	348	17	(	(	PUNCT
fnp-5842	348	18	edinger	edinger	PROPN
fnp-5842	348	19	institute	institute	PROPN
fnp-5842	348	20	)	)	PUNCT
fnp-5842	348	21	in	in	ADP
fnp-5842	348	22	frankfurt	frankfurt	PROPN
fnp-5842	348	23	,	,	PUNCT
fnp-5842	348	24	germany	germany	PROPN
fnp-5842	348	25	karl	karl	PROPN
fnp-5842	348	26	h.	h.	PROPN
fnp-5842	348	27	plate1	plate1	PROPN
fnp-5842	348	28	1	1	NUM
fnp-5842	348	29	goethe	goethe	PROPN
fnp-5842	348	30	university	university	NOUN
fnp-5842	348	31	,	,	PUNCT
fnp-5842	348	32	university	university	NOUN
fnp-5842	348	33	hospital	hospital	NOUN
fnp-5842	348	34	,	,	PUNCT
fnp-5842	348	35	institute	institute	NOUN
fnp-5842	348	36	of	of	ADP
fnp-5842	348	37	neurology	neurology	NOUN
fnp-5842	348	38	(	(	PUNCT
fnp-5842	348	39	edinger	edinger	PROPN
fnp-5842	348	40	institute	institute	PROPN
fnp-5842	348	41	)	)	PUNCT
fnp-5842	348	42	,	,	PUNCT
fnp-5842	348	43	frankfurt	frankfurt	PROPN
fnp-5842	348	44	,	,	PUNCT
fnp-5842	348	45	germany	germany	PROPN
fnp-5842	348	46	the	the	DET
fnp-5842	348	47	institute	institute	PROPN
fnp-5842	348	48	of	of	ADP
fnp-5842	348	49	neurology	neurology	NOUN
fnp-5842	348	50	was	be	AUX
fnp-5842	348	51	established	establish	VERB
fnp-5842	348	52	by	by	ADP
fnp-5842	348	53	the	the	DET
fnp-5842	348	54	jewish	jewish	ADJ
fnp-5842	348	55	neuroscientist	neuroscientist	NOUN
fnp-5842	348	56	ludwig	ludwig	PROPN
fnp-5842	348	57	edinger	edinger	NOUN
fnp-5842	348	58	on	on	ADP
fnp-5842	348	59	the	the	DET
fnp-5842	348	60	premises	premise	NOUN
fnp-5842	348	61	of	of	ADP
fnp-5842	348	62	the	the	DET
fnp-5842	348	63	dr	dr	PROPN
fnp-5842	348	64	.	.	PROPN
fnp-5842	348	65	senckenberg	senckenberg	PROPN
fnp-5842	348	66	institute	institute	PROPN
fnp-5842	348	67	of	of	ADP
fnp-5842	348	68	pathology	pathology	PROPN
fnp-5842	348	69	in	in	ADP
fnp-5842	348	70	frankfurt	frankfurt	PROPN
fnp-5842	348	71	,	,	PUNCT
fnp-5842	348	72	headed	head	VERB
fnp-5842	348	73	by	by	ADP
fnp-5842	348	74	carl	carl	PROPN
fnp-5842	348	75	weigert	weigert	PROPN
fnp-5842	348	76	.	.	PUNCT
fnp-5842	349	1	edinger	edinger	NOUN
fnp-5842	349	2	was	be	AUX
fnp-5842	349	3	considered	consider	VERB
fnp-5842	349	4	to	to	PART
fnp-5842	349	5	be	be	AUX
fnp-5842	349	6	the	the	DET
fnp-5842	349	7	leader	leader	NOUN
fnp-5842	349	8	in	in	ADP
fnp-5842	349	9	comparative	comparative	ADJ
fnp-5842	349	10	neuroscience	neuroscience	NOUN
fnp-5842	349	11	of	of	ADP
fnp-5842	349	12	its	its	PRON
fnp-5842	349	13	time	time	NOUN
fnp-5842	349	14	by	by	ADP
fnp-5842	349	15	the	the	DET
fnp-5842	349	16	spanish	spanish	ADJ
fnp-5842	349	17	nobel	nobel	PROPN
fnp-5842	349	18	prize	prize	PROPN
fnp-5842	349	19	winner	winner	NOUN
fnp-5842	349	20	ramon	ramon	PROPN
fnp-5842	349	21	y	y	PROPN
fnp-5842	349	22	cajal	cajal	PROPN
fnp-5842	349	23	.	.	PUNCT
fnp-5842	350	1	edinger	edinger	ADV
fnp-5842	350	2	was	be	AUX
fnp-5842	350	3	among	among	ADP
fnp-5842	350	4	the	the	DET
fnp-5842	350	5	founders	founder	NOUN
fnp-5842	350	6	of	of	ADP
fnp-5842	350	7	the	the	DET
fnp-5842	350	8	“	"	PUNCT
fnp-5842	350	9	königliche	königliche	X
fnp-5842	350	10	universität	universität	PROPN
fnp-5842	350	11	zu	zu	PROPN
fnp-5842	350	12	frankfurt	frankfurt	PROPN
fnp-5842	350	13	”	"	PUNCT
fnp-5842	350	14	(	(	PUNCT
fnp-5842	350	15	later	later	ADV
fnp-5842	350	16	renamed	rename	VERB
fnp-5842	350	17	as	as	ADP
fnp-5842	350	18	goethe	goethe	PROPN
fnp-5842	350	19	university	university	NOUN
fnp-5842	350	20	)	)	PUNCT
fnp-5842	350	21	in	in	ADP
fnp-5842	350	22	1914	1914	NUM
fnp-5842	350	23	and	and	CCONJ
fnp-5842	350	24	was	be	AUX
fnp-5842	350	25	appointed	appoint	VERB
fnp-5842	350	26	as	as	ADP
fnp-5842	350	27	the	the	DET
fnp-5842	350	28	first	first	ADJ
fnp-5842	350	29	professor	professor	NOUN
fnp-5842	350	30	of	of	ADP
fnp-5842	350	31	neurology	neurology	NOUN
fnp-5842	350	32	in	in	ADP
fnp-5842	350	33	germany	germany	PROPN
fnp-5842	350	34	.	.	PUNCT
fnp-5842	351	1	during	during	ADP
fnp-5842	351	2	the	the	DET
fnp-5842	351	3	“	"	PUNCT
fnp-5842	351	4	third	third	ADJ
fnp-5842	351	5	reich	reich	NOUN
fnp-5842	351	6	”	"	PUNCT
fnp-5842	351	7	,	,	PUNCT
fnp-5842	351	8	jewish	jewish	ADJ
fnp-5842	351	9	scientists	scientist	NOUN
fnp-5842	351	10	,	,	PUNCT
fnp-5842	351	11	including	include	VERB
fnp-5842	351	12	edinger	edinger	NOUN
fnp-5842	351	13	's	's	PART
fnp-5842	351	14	successor	successor	NOUN
fnp-5842	351	15	kurt	kurt	PROPN
fnp-5842	351	16	goldstein	goldstein	PROPN
fnp-5842	351	17	,	,	PUNCT
fnp-5842	351	18	were	be	AUX
fnp-5842	351	19	forced	force	VERB
fnp-5842	351	20	to	to	PART
fnp-5842	351	21	leave	leave	VERB
fnp-5842	351	22	the	the	DET
fnp-5842	351	23	institute	institute	NOUN
fnp-5842	351	24	.	.	PUNCT
fnp-5842	352	1	as	as	ADP
fnp-5842	352	2	a	a	DET
fnp-5842	352	3	consequence	consequence	NOUN
fnp-5842	352	4	,	,	PUNCT
fnp-5842	352	5	scientific	scientific	ADJ
fnp-5842	352	6	activities	activity	NOUN
fnp-5842	352	7	in	in	ADP
fnp-5842	352	8	the	the	DET
fnp-5842	352	9	institute	institute	PROPN
fnp-5842	352	10	of	of	ADP
fnp-5842	352	11	neurology	neurology	NOUN
fnp-5842	352	12	ceased	cease	VERB
fnp-5842	352	13	almost	almost	ADV
fnp-5842	352	14	completely	completely	ADV
fnp-5842	352	15	.	.	PUNCT
fnp-5842	353	1	after	after	ADP
fnp-5842	353	2	wwii	wwii	PROPN
fnp-5842	353	3	,	,	PUNCT
fnp-5842	353	4	wilhelm	wilhelm	PROPN
fnp-5842	353	5	krücke	krücke	PROPN
fnp-5842	353	6	,	,	PUNCT
fnp-5842	353	7	an	an	DET
fnp-5842	353	8	expert	expert	NOUN
fnp-5842	353	9	on	on	ADP
fnp-5842	353	10	peripheral	peripheral	ADJ
fnp-5842	353	11	neuropathies	neuropathy	NOUN
fnp-5842	353	12	,	,	PUNCT
fnp-5842	353	13	became	become	VERB
fnp-5842	353	14	the	the	DET
fnp-5842	353	15	director	director	NOUN
fnp-5842	353	16	of	of	ADP
fnp-5842	353	17	the	the	DET
fnp-5842	353	18	institute	institute	NOUN
fnp-5842	353	19	and	and	CCONJ
fnp-5842	353	20	founder	founder	NOUN
fnp-5842	353	21	of	of	ADP
fnp-5842	353	22	the	the	DET
fnp-5842	353	23	german	german	ADJ
fnp-5842	353	24	society	society	NOUN
fnp-5842	353	25	of	of	ADP
fnp-5842	353	26	neuropathology	neuropathology	NOUN
fnp-5842	353	27	in	in	ADP
fnp-5842	353	28	1950	1950	NUM
fnp-5842	353	29	.	.	PUNCT
fnp-5842	354	1	in	in	ADP
fnp-5842	354	2	1960	1960	NUM
fnp-5842	354	3	,	,	PUNCT
fnp-5842	354	4	the	the	DET
fnp-5842	354	5	edinger	edinger	PROPN
fnp-5842	354	6	institute	institute	NOUN
fnp-5842	354	7	served	serve	VERB
fnp-5842	354	8	as	as	ADP
fnp-5842	354	9	founder	founder	NOUN
fnp-5842	354	10	for	for	ADP
fnp-5842	354	11	the	the	DET
fnp-5842	354	12	max	max	PROPN
fnp-5842	354	13	-	-	PUNCT
fnp-5842	354	14	planck	planck	NOUN
fnp-5842	354	15	institute	institute	NOUN
fnp-5842	354	16	for	for	ADP
fnp-5842	354	17	brain	brain	NOUN
fnp-5842	354	18	research	research	NOUN
fnp-5842	354	19	,	,	PUNCT
fnp-5842	354	20	the	the	DET
fnp-5842	354	21	legal	legal	ADJ
fnp-5842	354	22	successor	successor	NOUN
fnp-5842	354	23	of	of	ADP
fnp-5842	354	24	the	the	DET
fnp-5842	354	25	kaiser	kaiser	PROPN
fnp-5842	354	26	-	-	PUNCT
fnp-5842	354	27	wilhelm	wilhelm	PROPN
fnp-5842	354	28	institute	institute	PROPN
fnp-5842	354	29	for	for	ADP
fnp-5842	354	30	brain	brain	NOUN
fnp-5842	354	31	research	research	NOUN
fnp-5842	354	32	(	(	PUNCT
fnp-5842	354	33	kwih	kwih	PROPN
fnp-5842	354	34	,	,	PUNCT
fnp-5842	354	35	established	establish	VERB
fnp-5842	354	36	1914	1914	NUM
fnp-5842	354	37	)	)	PUNCT
fnp-5842	354	38	.	.	PUNCT
fnp-5842	355	1	as	as	ADP
fnp-5842	355	2	a	a	DET
fnp-5842	355	3	consequence	consequence	NOUN
fnp-5842	355	4	of	of	ADP
fnp-5842	355	5	the	the	DET
fnp-5842	355	6	merger	merger	NOUN
fnp-5842	355	7	of	of	ADP
fnp-5842	355	8	edinger	edinger	NOUN
fnp-5842	355	9	's	's	PART
fnp-5842	355	10	institute	institute	NOUN
fnp-5842	355	11	with	with	ADP
fnp-5842	355	12	the	the	DET
fnp-5842	355	13	department	department	PROPN
fnp-5842	355	14	of	of	ADP
fnp-5842	355	15	histopathology	histopathology	NOUN
fnp-5842	355	16	of	of	ADP
fnp-5842	355	17	the	the	DET
fnp-5842	355	18	former	former	ADJ
fnp-5842	355	19	kwih	kwih	NOUN
fnp-5842	355	20	,	,	PUNCT
fnp-5842	355	21	previously	previously	ADV
fnp-5842	355	22	unrecognized	unrecognize	VERB
fnp-5842	355	23	specimens	specimen	NOUN
fnp-5842	355	24	of	of	ADP
fnp-5842	355	25	victims	victim	NOUN
fnp-5842	355	26	of	of	ADP
fnp-5842	355	27	the	the	DET
fnp-5842	355	28	nazi	nazi	NOUN
fnp-5842	355	29	-	-	PUNCT
fnp-5842	355	30	regime	regime	NOUN
fnp-5842	355	31	were	be	AUX
fnp-5842	355	32	detected	detect	VERB
fnp-5842	355	33	.	.	PUNCT
fnp-5842	356	1	wolfgang	wolfgang	PROPN
fnp-5842	356	2	schlote	schlote	PROPN
fnp-5842	356	3	became	become	VERB
fnp-5842	356	4	the	the	DET
fnp-5842	356	5	director	director	NOUN
fnp-5842	356	6	of	of	ADP
fnp-5842	356	7	the	the	DET
fnp-5842	356	8	institute	institute	NOUN
fnp-5842	356	9	in	in	ADP
fnp-5842	356	10	1984	1984	NUM
fnp-5842	356	11	until	until	ADP
fnp-5842	356	12	his	his	PRON
fnp-5842	356	13	retirement	retirement	NOUN
fnp-5842	356	14	in	in	ADP
fnp-5842	356	15	1999	1999	NUM
fnp-5842	356	16	.	.	PUNCT
fnp-5842	357	1	this	this	DET
fnp-5842	357	2	position	position	NOUN
fnp-5842	357	3	was	be	AUX
fnp-5842	357	4	carried	carry	VERB
fnp-5842	357	5	on	on	ADP
fnp-5842	357	6	by	by	ADP
fnp-5842	357	7	karl	karl	PROPN
fnp-5842	357	8	h.	h.	PROPN
fnp-5842	357	9	plate	plate	PROPN
fnp-5842	357	10	in	in	ADP
fnp-5842	357	11	2001	2001	NUM
fnp-5842	357	12	.	.	PUNCT
fnp-5842	358	1	the	the	DET
fnp-5842	358	2	year	year	NOUN
fnp-5842	358	3	2002	2002	NUM
fnp-5842	358	4	marked	mark	VERB
fnp-5842	358	5	the	the	DET
fnp-5842	358	6	100th	100th	ADJ
fnp-5842	358	7	anniversary	anniversary	NOUN
fnp-5842	358	8	of	of	ADP
fnp-5842	358	9	the	the	DET
fnp-5842	358	10	edinger	edinger	PROPN
fnp-5842	358	11	institute	institute	NOUN
fnp-5842	358	12	.	.	PUNCT
fnp-5842	359	1	several	several	ADJ
fnp-5842	359	2	members	member	NOUN
fnp-5842	359	3	of	of	ADP
fnp-5842	359	4	the	the	DET
fnp-5842	359	5	edinger	edinger	ADJ
fnp-5842	359	6	family	family	NOUN
fnp-5842	359	7	returned	return	VERB
fnp-5842	359	8	to	to	ADP
fnp-5842	359	9	germany	germany	PROPN
fnp-5842	359	10	for	for	ADP
fnp-5842	359	11	the	the	DET
fnp-5842	359	12	first	first	ADJ
fnp-5842	359	13	time	time	NOUN
fnp-5842	359	14	after	after	ADP
fnp-5842	359	15	wwii	wwii	PROPN
fnp-5842	359	16	on	on	ADP
fnp-5842	359	17	this	this	DET
fnp-5842	359	18	occasion	occasion	NOUN
fnp-5842	359	19	.	.	PUNCT
fnp-5842	360	1	122	122	NUM
fnp-5842	360	2	years	year	NOUN
fnp-5842	360	3	after	after	ADP
fnp-5842	360	4	its	its	PRON
fnp-5842	360	5	foundation	foundation	NOUN
fnp-5842	360	6	,	,	PUNCT
fnp-5842	360	7	the	the	DET
fnp-5842	360	8	institute	institute	PROPN
fnp-5842	360	9	of	of	ADP
fnp-5842	360	10	neurology	neurology	NOUN
fnp-5842	360	11	continues	continue	VERB
fnp-5842	360	12	to	to	PART
fnp-5842	360	13	serve	serve	VERB
fnp-5842	360	14	as	as	ADP
fnp-5842	360	15	the	the	DET
fnp-5842	360	16	department	department	NOUN
fnp-5842	360	17	of	of	ADP
fnp-5842	360	18	neuropathology	neuropathology	NOUN
fnp-5842	360	19	of	of	ADP
fnp-5842	360	20	frankfurt	frankfurt	PROPN
fnp-5842	360	21	university	university	PROPN
fnp-5842	360	22	hospital	hospital	NOUN
fnp-5842	360	23	,	,	PUNCT
fnp-5842	360	24	hosting	host	VERB
fnp-5842	360	25	three	three	NUM
fnp-5842	360	26	professors	professor	NOUN
fnp-5842	360	27	and	and	CCONJ
fnp-5842	360	28	six	six	NUM
fnp-5842	360	29	research	research	NOUN
fnp-5842	360	30	groups	group	NOUN
fnp-5842	360	31	,	,	PUNCT
fnp-5842	360	32	consisting	consist	VERB
fnp-5842	360	33	of	of	ADP
fnp-5842	360	34	neuropathologists	neuropathologist	NOUN
fnp-5842	360	35	,	,	PUNCT
fnp-5842	360	36	molecular	molecular	ADJ
fnp-5842	360	37	biologists	biologist	NOUN
fnp-5842	360	38	,	,	PUNCT
fnp-5842	360	39	developmental	developmental	ADJ
fnp-5842	360	40	biologists	biologist	NOUN
fnp-5842	360	41	,	,	PUNCT
fnp-5842	360	42	bioinformaticians	bioinformatician	NOUN
fnp-5842	360	43	and	and	CCONJ
fnp-5842	360	44	research	research	NOUN
fnp-5842	360	45	staff	staff	NOUN
fnp-5842	360	46	to	to	PART
fnp-5842	360	47	provide	provide	VERB
fnp-5842	360	48	a	a	DET
fnp-5842	360	49	unique	unique	ADJ
fnp-5842	360	50	,	,	PUNCT
fnp-5842	360	51	lively	lively	ADJ
fnp-5842	360	52	environment	environment	NOUN
fnp-5842	360	53	for	for	ADP
fnp-5842	360	54	translational	translational	ADJ
fnp-5842	360	55	neuropathology	neuropathology	NOUN
fnp-5842	360	56	,	,	PUNCT
fnp-5842	360	57	coming	come	VERB
fnp-5842	360	58	close	close	ADV
fnp-5842	360	59	to	to	ADP
fnp-5842	360	60	how	how	SCONJ
fnp-5842	360	61	it	it	PRON
fnp-5842	360	62	was	be	AUX
fnp-5842	360	63	initially	initially	ADV
fnp-5842	360	64	intended	intend	VERB
fnp-5842	360	65	by	by	ADP
fnp-5842	360	66	its	its	PRON
fnp-5842	360	67	founder	founder	NOUN
fnp-5842	360	68	ludwig	ludwig	PROPN
fnp-5842	360	69	edinger	edinger	PROPN
fnp-5842	360	70	.	.	PUNCT
fnp-5842	361	1	p29	p29	PROPN
fnp-5842	361	2	free	free	ADJ
fnp-5842	361	3	neuropathol	neuropathol	NOUN
fnp-5842	361	4	5:19:43	5:19:43	NUM
fnp-5842	361	5	paving	pave	VERB
fnp-5842	361	6	the	the	DET
fnp-5842	361	7	path	path	NOUN
fnp-5842	361	8	:	:	PUNCT
fnp-5842	361	9	the	the	DET
fnp-5842	361	10	powerful	powerful	ADJ
fnp-5842	361	11	effect	effect	NOUN
fnp-5842	361	12	of	of	ADP
fnp-5842	361	13	substrate	substrate	NOUN
fnp-5842	361	14	topography	topography	NOUN
fnp-5842	361	15	on	on	ADP
fnp-5842	361	16	axon	axon	NOUN
fnp-5842	361	17	-	-	PUNCT
fnp-5842	361	18	repulsive	repulsive	ADJ
fnp-5842	361	19	schwann	schwann	PROPN
fnp-5842	361	20	cell	cell	NOUN
fnp-5842	361	21	-	-	PUNCT
fnp-5842	361	22	astrocyte	astrocyte	NOUN
fnp-5842	361	23	barrier	barrier	NOUN
fnp-5842	361	24	formation	formation	NOUN
fnp-5842	361	25	for	for	ADP
fnp-5842	361	26	spinal	spinal	ADJ
fnp-5842	361	27	cord	cord	NOUN
fnp-5842	361	28	injury	injury	NOUN
fnp-5842	361	29	repair	repair	PROPN
fnp-5842	361	30	pascal	pascal	PROPN
fnp-5842	361	31	achenbach1	achenbach1	PROPN
fnp-5842	361	32	,	,	PUNCT
fnp-5842	361	33	laura	laura	PROPN
fnp-5842	361	34	hillerbrand2	hillerbrand2	PROPN
fnp-5842	361	35	,	,	PUNCT
fnp-5842	361	36	josé	josé	PROPN
fnp-5842	361	37	l.	l.	PROPN
fnp-5842	361	38	gerardo	gerardo	PROPN
fnp-5842	361	39	-	-	PUNCT
fnp-5842	361	40	nava3,4	nava3,4	PROPN
fnp-5842	361	41	,	,	PUNCT
fnp-5842	361	42	axel	axel	PROPN
fnp-5842	361	43	dievernich5,6	dievernich5,6	PROPN
fnp-5842	361	44	,	,	PUNCT
fnp-5842	361	45	dorothee	dorothee	PROPN
fnp-5842	361	46	hodde1,7	hodde1,7	PROPN
fnp-5842	361	47	,	,	PUNCT
fnp-5842	361	48	antonio	antonio	PROPN
fnp-5842	361	49	sechi8	sechi8	PROPN
fnp-5842	361	50	,	,	PUNCT
fnp-5842	361	51	paul	paul	PROPN
fnp-5842	361	52	d.	d.	PROPN
fnp-5842	361	53	dalton9	dalton9	PROPN
fnp-5842	361	54	,	,	PUNCT
fnp-5842	361	55	andrij	andrij	PROPN
fnp-5842	361	56	pich3,10	pich3,10	PROPN
fnp-5842	361	57	,	,	PUNCT
fnp-5842	361	58	joachim	joachim	PROPN
fnp-5842	361	59	weis1	weis1	PROPN
fnp-5842	361	60	,	,	PUNCT
fnp-5842	361	61	haktan	haktan	PROPN
fnp-5842	361	62	altinova1,11,12	altinova1,11,12	PROPN
fnp-5842	361	63	,	,	PUNCT
fnp-5842	361	64	gary	gary	PROPN
fnp-5842	361	65	a.	a.	PROPN
fnp-5842	361	66	brook1	brook1	PROPN
fnp-5842	361	67	1	1	NUM
fnp-5842	361	68	institute	institute	PROPN
fnp-5842	361	69	of	of	ADP
fnp-5842	361	70	neuropathology	neuropathology	NOUN
fnp-5842	361	71	,	,	PUNCT
fnp-5842	361	72	rwth	rwth	PROPN
fnp-5842	361	73	aachen	aachen	PROPN
fnp-5842	361	74	university	university	PROPN
fnp-5842	361	75	hospital	hospital	NOUN
fnp-5842	361	76	,	,	PUNCT
fnp-5842	361	77	aachen	aachen	PROPN
fnp-5842	361	78	,	,	PUNCT
fnp-5842	361	79	germany	germany	PROPN
fnp-5842	361	80	2	2	NUM
fnp-5842	361	81	department	department	NOUN
fnp-5842	361	82	of	of	ADP
fnp-5842	361	83	functional	functional	ADJ
fnp-5842	361	84	materials	material	NOUN
fnp-5842	361	85	in	in	ADP
fnp-5842	361	86	medicine	medicine	NOUN
fnp-5842	361	87	and	and	CCONJ
fnp-5842	361	88	dentistry	dentistry	NOUN
fnp-5842	361	89	,	,	PUNCT
fnp-5842	361	90	university	university	NOUN
fnp-5842	361	91	hospital	hospital	NOUN
fnp-5842	361	92	würzburg	würzburg	NOUN
fnp-5842	361	93	,	,	PUNCT
fnp-5842	361	94	würzburg	würzburg	NOUN
fnp-5842	361	95	,	,	PUNCT
fnp-5842	361	96	germany	germany	PROPN
fnp-5842	361	97	3	3	NUM
fnp-5842	361	98	dwi	dwi	PROPN
fnp-5842	361	99	leibniz	leibniz	PROPN
fnp-5842	361	100	institute	institute	PROPN
fnp-5842	361	101	for	for	ADP
fnp-5842	361	102	interactive	interactive	ADJ
fnp-5842	361	103	materials	material	NOUN
fnp-5842	361	104	,	,	PUNCT
fnp-5842	361	105	aachen	aachen	PROPN
fnp-5842	361	106	,	,	PUNCT
fnp-5842	361	107	germany	germany	PROPN
fnp-5842	361	108	4	4	NUM
fnp-5842	361	109	advanced	advanced	ADJ
fnp-5842	361	110	materials	material	NOUN
fnp-5842	361	111	for	for	ADP
fnp-5842	361	112	biomedicine	biomedicine	NOUN
fnp-5842	361	113	(	(	PUNCT
fnp-5842	361	114	amb	amb	PROPN
fnp-5842	361	115	)	)	PUNCT
fnp-5842	361	116	,	,	PUNCT
fnp-5842	361	117	institute	institute	NOUN
fnp-5842	361	118	of	of	ADP
fnp-5842	361	119	applied	apply	VERB
fnp-5842	361	120	medical	medical	ADJ
fnp-5842	361	121	engineering	engineering	NOUN
fnp-5842	361	122	(	(	PUNCT
fnp-5842	361	123	ame	ame	PROPN
fnp-5842	361	124	)	)	PUNCT
fnp-5842	361	125	,	,	PUNCT
fnp-5842	361	126	rwth	rwth	NOUN
fnp-5842	361	127	aachen	aachen	PROPN
fnp-5842	361	128	university	university	PROPN
fnp-5842	361	129	hospital	hospital	NOUN
fnp-5842	361	130	,	,	PUNCT
fnp-5842	361	131	aachen	aachen	PROPN
fnp-5842	361	132	,	,	PUNCT
fnp-5842	361	133	germany	germany	PROPN
fnp-5842	361	134	5	5	NUM
fnp-5842	361	135	feg	feg	PROPN
fnp-5842	361	136	textiltechnik	textiltechnik	PROPN
fnp-5842	361	137	forschungsund	forschungsund	PROPN
fnp-5842	361	138	entwicklungsgesellschaft	entwicklungsgesellschaft	PROPN
fnp-5842	361	139	mbh	mbh	PROPN
fnp-5842	361	140	,	,	PUNCT
fnp-5842	361	141	aachen	aachen	PROPN
fnp-5842	361	142	,	,	PUNCT
fnp-5842	361	143	germany	germany	PROPN
fnp-5842	361	144	6	6	NUM
fnp-5842	361	145	institute	institute	PROPN
fnp-5842	361	146	of	of	ADP
fnp-5842	361	147	laboratory	laboratory	NOUN
fnp-5842	361	148	animal	animal	NOUN
fnp-5842	361	149	science	science	NOUN
fnp-5842	361	150	,	,	PUNCT
fnp-5842	361	151	rwth	rwth	PROPN
fnp-5842	361	152	aachen	aachen	PROPN
fnp-5842	361	153	university	university	PROPN
fnp-5842	361	154	hospital	hospital	NOUN
fnp-5842	361	155	,	,	PUNCT
fnp-5842	361	156	aachen	aachen	PROPN
fnp-5842	361	157	,	,	PUNCT
fnp-5842	361	158	germany	germany	PROPN
fnp-5842	361	159	7	7	NUM
fnp-5842	361	160	hospital	hospital	NOUN
fnp-5842	361	161	of	of	ADP
fnp-5842	361	162	the	the	DET
fnp-5842	361	163	ludwig	ludwig	PROPN
fnp-5842	361	164	maximilians	maximilians	PROPN
fnp-5842	361	165	university	university	PROPN
fnp-5842	361	166	munich	munich	PROPN
fnp-5842	361	167	,	,	PUNCT
fnp-5842	361	168	munich	munich	PROPN
fnp-5842	361	169	,	,	PUNCT
fnp-5842	361	170	germany	germany	PROPN
fnp-5842	361	171	8	8	NUM
fnp-5842	361	172	department	department	NOUN
fnp-5842	361	173	of	of	ADP
fnp-5842	361	174	cell	cell	NOUN
fnp-5842	361	175	and	and	CCONJ
fnp-5842	361	176	tumor	tumor	NOUN
fnp-5842	361	177	biology	biology	NOUN
fnp-5842	361	178	,	,	PUNCT
fnp-5842	361	179	rwth	rwth	NOUN
fnp-5842	361	180	aachen	aachen	PROPN
fnp-5842	361	181	university	university	PROPN
fnp-5842	361	182	hospital	hospital	NOUN
fnp-5842	361	183	,	,	PUNCT
fnp-5842	361	184	aachen	aachen	PROPN
fnp-5842	361	185	,	,	PUNCT
fnp-5842	361	186	germany	germany	PROPN
fnp-5842	361	187	9	9	NUM
fnp-5842	361	188	phil	phil	NOUN
fnp-5842	361	189	and	and	CCONJ
fnp-5842	361	190	penny	penny	NOUN
fnp-5842	361	191	knight	knight	NOUN
fnp-5842	361	192	campus	campus	NOUN
fnp-5842	361	193	for	for	ADP
fnp-5842	361	194	accelerating	accelerate	VERB
fnp-5842	361	195	scientific	scientific	ADJ
fnp-5842	361	196	impact	impact	NOUN
fnp-5842	361	197	,	,	PUNCT
fnp-5842	361	198	university	university	NOUN
fnp-5842	361	199	of	of	ADP
fnp-5842	361	200	oregon	oregon	PROPN
fnp-5842	361	201	,	,	PUNCT
fnp-5842	361	202	eugene	eugene	NOUN
fnp-5842	361	203	,	,	PUNCT
fnp-5842	361	204	oregon	oregon	PROPN
fnp-5842	361	205	,	,	PUNCT
fnp-5842	361	206	united	united	PROPN
fnp-5842	361	207	states	states	PROPN
fnp-5842	361	208	10	10	NUM
fnp-5842	361	209	institute	institute	PROPN
fnp-5842	361	210	of	of	ADP
fnp-5842	361	211	technical	technical	ADJ
fnp-5842	361	212	and	and	CCONJ
fnp-5842	361	213	macromolecular	macromolecular	ADJ
fnp-5842	361	214	chemistry	chemistry	NOUN
fnp-5842	361	215	,	,	PUNCT
fnp-5842	361	216	rwth	rwth	PROPN
fnp-5842	361	217	aachen	aachen	PROPN
fnp-5842	361	218	university	university	PROPN
fnp-5842	361	219	,	,	PUNCT
fnp-5842	361	220	aachen	aachen	PROPN
fnp-5842	361	221	,	,	PUNCT
fnp-5842	361	222	germany	germany	PROPN
fnp-5842	361	223	11	11	NUM
fnp-5842	361	224	department	department	NOUN
fnp-5842	361	225	of	of	ADP
fnp-5842	361	226	neurosurgery	neurosurgery	NOUN
fnp-5842	361	227	,	,	PUNCT
fnp-5842	361	228	rwth	rwth	PROPN
fnp-5842	361	229	aachen	aachen	PROPN
fnp-5842	361	230	university	university	PROPN
fnp-5842	361	231	hospital	hospital	NOUN
fnp-5842	361	232	,	,	PUNCT
fnp-5842	361	233	aachen	aachen	PROPN
fnp-5842	361	234	,	,	PUNCT
fnp-5842	361	235	germany	germany	PROPN
fnp-5842	361	236	12	12	NUM
fnp-5842	361	237	berlin	berlin	PROPN
fnp-5842	361	238	state	state	NOUN
fnp-5842	361	239	office	office	NOUN
fnp-5842	361	240	for	for	ADP
fnp-5842	361	241	health	health	NOUN
fnp-5842	361	242	and	and	CCONJ
fnp-5842	361	243	social	social	ADJ
fnp-5842	361	244	affairs	affair	NOUN
fnp-5842	361	245	(	(	PUNCT
fnp-5842	361	246	lageso	lageso	PROPN
fnp-5842	361	247	)	)	PUNCT
fnp-5842	361	248	,	,	PUNCT
fnp-5842	361	249	berlin	berlin	PROPN
fnp-5842	361	250	,	,	PUNCT
fnp-5842	361	251	germany	germany	PROPN
fnp-5842	361	252	spinal	spinal	PROPN
fnp-5842	361	253	cord	cord	NOUN
fnp-5842	361	254	injury	injury	NOUN
fnp-5842	361	255	is	be	AUX
fnp-5842	361	256	a	a	DET
fnp-5842	361	257	devastating	devastating	ADJ
fnp-5842	361	258	condition	condition	NOUN
fnp-5842	361	259	that	that	PRON
fnp-5842	361	260	leads	lead	VERB
fnp-5842	361	261	to	to	ADP
fnp-5842	361	262	permanent	permanent	ADJ
fnp-5842	361	263	impairment	impairment	NOUN
fnp-5842	361	264	of	of	ADP
fnp-5842	361	265	sensory	sensory	NOUN
fnp-5842	361	266	,	,	PUNCT
fnp-5842	361	267	motor	motor	NOUN
fnp-5842	361	268	and	and	CCONJ
fnp-5842	361	269	autonomous	autonomous	ADJ
fnp-5842	361	270	functions	function	NOUN
fnp-5842	361	271	.	.	PUNCT
fnp-5842	362	1	the	the	DET
fnp-5842	362	2	severely	severely	ADV
fnp-5842	362	3	limited	limit	VERB
fnp-5842	362	4	regenerative	regenerative	ADJ
fnp-5842	362	5	capacity	capacity	NOUN
fnp-5842	362	6	of	of	ADP
fnp-5842	362	7	the	the	DET
fnp-5842	362	8	lesioned	lesione	VERB
fnp-5842	362	9	central	central	ADJ
fnp-5842	362	10	nervous	nervous	ADJ
fnp-5842	362	11	system	system	NOUN
fnp-5842	362	12	(	(	PUNCT
fnp-5842	362	13	cns	cns	NOUN
fnp-5842	362	14	)	)	PUNCT
fnp-5842	362	15	is	be	AUX
fnp-5842	362	16	mainly	mainly	ADV
fnp-5842	362	17	attributed	attribute	VERB
fnp-5842	362	18	to	to	ADP
fnp-5842	362	19	the	the	DET
fnp-5842	362	20	formation	formation	NOUN
fnp-5842	362	21	of	of	ADP
fnp-5842	362	22	a	a	DET
fnp-5842	362	23	glial	glial	ADJ
fnp-5842	362	24	scar	scar	NOUN
fnp-5842	362	25	,	,	PUNCT
fnp-5842	362	26	a	a	DET
fnp-5842	362	27	process	process	NOUN
fnp-5842	362	28	that	that	PRON
fnp-5842	362	29	is	be	AUX
fnp-5842	362	30	mediated	mediate	VERB
fnp-5842	362	31	by	by	ADP
fnp-5842	362	32	reactive	reactive	ADJ
fnp-5842	362	33	astrocytes	astrocyte	NOUN
fnp-5842	362	34	(	(	PUNCT
fnp-5842	362	35	acs	acs	PROPN
fnp-5842	362	36	)	)	PUNCT
fnp-5842	362	37	.	.	PUNCT
fnp-5842	363	1	transplantation	transplantation	NOUN
fnp-5842	363	2	of	of	ADP
fnp-5842	363	3	schwann	schwann	PROPN
fnp-5842	363	4	cells	cell	NOUN
fnp-5842	363	5	(	(	PUNCT
fnp-5842	363	6	scs	scs	PROPN
fnp-5842	363	7	)	)	PUNCT
fnp-5842	363	8	into	into	ADP
fnp-5842	363	9	the	the	DET
fnp-5842	363	10	severed	sever	VERB
fnp-5842	363	11	spinal	spinal	NOUN
fnp-5842	363	12	cord	cord	NOUN
fnp-5842	363	13	represents	represent	VERB
fnp-5842	363	14	a	a	DET
fnp-5842	363	15	promising	promising	ADJ
fnp-5842	363	16	therapeutic	therapeutic	ADJ
fnp-5842	363	17	approach	approach	NOUN
fnp-5842	363	18	to	to	PART
fnp-5842	363	19	support	support	VERB
fnp-5842	363	20	tissue	tissue	NOUN
fnp-5842	363	21	regeneration	regeneration	NOUN
fnp-5842	363	22	but	but	CCONJ
fnp-5842	363	23	is	be	AUX
fnp-5842	363	24	limited	limit	VERB
fnp-5842	363	25	by	by	ADP
fnp-5842	363	26	mutually	mutually	ADV
fnp-5842	363	27	repulsive	repulsive	ADJ
fnp-5842	363	28	interactions	interaction	NOUN
fnp-5842	363	29	with	with	ADP
fnp-5842	363	30	resident	resident	ADJ
fnp-5842	363	31	acs	acs	PROPN
fnp-5842	363	32	,	,	PUNCT
fnp-5842	363	33	resulting	result	VERB
fnp-5842	363	34	in	in	ADP
fnp-5842	363	35	the	the	DET
fnp-5842	363	36	formation	formation	NOUN
fnp-5842	363	37	of	of	ADP
fnp-5842	363	38	well	well	ADV
fnp-5842	363	39	-	-	PUNCT
fnp-5842	363	40	defined	define	VERB
fnp-5842	363	41	interfaces	interface	NOUN
fnp-5842	363	42	.	.	PUNCT
fnp-5842	364	1	such	such	ADJ
fnp-5842	364	2	interfaces	interface	NOUN
fnp-5842	364	3	act	act	VERB
fnp-5842	364	4	as	as	ADP
fnp-5842	364	5	effective	effective	ADJ
fnp-5842	364	6	barriers	barrier	NOUN
fnp-5842	364	7	for	for	ADP
fnp-5842	364	8	regenerating	regenerate	VERB
fnp-5842	364	9	axons	axon	NOUN
fnp-5842	364	10	,	,	PUNCT
fnp-5842	364	11	allowing	allow	VERB
fnp-5842	364	12	the	the	DET
fnp-5842	364	13	transition	transition	NOUN
fnp-5842	364	14	from	from	ADP
fnp-5842	364	15	the	the	DET
fnp-5842	364	16	ac	ac	PROPN
fnp-5842	364	17	-	-	PUNCT
fnp-5842	364	18	dominated	dominate	VERB
fnp-5842	364	19	cns	cns	NOUN
fnp-5842	364	20	environment	environment	NOUN
fnp-5842	364	21	into	into	ADP
fnp-5842	364	22	the	the	DET
fnp-5842	364	23	sc	sc	PROPN
fnp-5842	364	24	compartment	compartment	NOUN
fnp-5842	364	25	but	but	CCONJ
fnp-5842	364	26	not	not	PART
fnp-5842	364	27	vice	vice	ADV
fnp-5842	364	28	versa	versa	ADV
fnp-5842	364	29	,	,	PUNCT
fnp-5842	364	30	leaving	leave	VERB
fnp-5842	364	31	regenerated	regenerated	ADJ
fnp-5842	364	32	axons	axon	NOUN
fnp-5842	364	33	trapped	trap	VERB
fnp-5842	364	34	within	within	ADP
fnp-5842	364	35	the	the	DET
fnp-5842	364	36	sc	sc	PROPN
fnp-5842	364	37	graft	graft	NOUN
fnp-5842	364	38	.	.	PUNCT
fnp-5842	365	1	for	for	ADP
fnp-5842	365	2	this	this	DET
fnp-5842	365	3	investigation	investigation	NOUN
fnp-5842	365	4	,	,	PUNCT
fnp-5842	365	5	the	the	DET
fnp-5842	365	6	well	well	ADV
fnp-5842	365	7	-	-	PUNCT
fnp-5842	365	8	established	establish	VERB
fnp-5842	365	9	confrontation	confrontation	NOUN
fnp-5842	365	10	assay	assay	NOUN
fnp-5842	365	11	model	model	NOUN
fnp-5842	365	12	was	be	AUX
fnp-5842	365	13	adapted	adapt	VERB
fnp-5842	365	14	to	to	PART
fnp-5842	365	15	study	study	VERB
fnp-5842	365	16	the	the	DET
fnp-5842	365	17	effect	effect	NOUN
fnp-5842	365	18	of	of	ADP
fnp-5842	365	19	topographical	topographical	ADJ
fnp-5842	365	20	cues	cue	NOUN
fnp-5842	365	21	derived	derive	VERB
fnp-5842	365	22	from	from	ADP
fnp-5842	365	23	substrate	substrate	NOUN
fnp-5842	365	24	-	-	PUNCT
fnp-5842	365	25	bound	bind	VERB
fnp-5842	365	26	,	,	PUNCT
fnp-5842	365	27	highly	highly	ADV
fnp-5842	365	28	oriented	orient	VERB
fnp-5842	365	29	poly(ε	poly(ε	NOUN
fnp-5842	365	30	-	-	PUNCT
fnp-5842	365	31	caprolactone	caprolactone	NOUN
fnp-5842	365	32	)	)	PUNCT
fnp-5842	365	33	nanofibers	nanofiber	NOUN
fnp-5842	365	34	on	on	ADP
fnp-5842	365	35	such	such	ADJ
fnp-5842	365	36	devastating	devastating	ADJ
fnp-5842	365	37	sc	sc	ADJ
fnp-5842	365	38	-	-	PUNCT
fnp-5842	365	39	ac	ac	PROPN
fnp-5842	365	40	interactions	interaction	NOUN
fnp-5842	365	41	as	as	ADV
fnp-5842	365	42	well	well	ADV
fnp-5842	365	43	as	as	ADP
fnp-5842	365	44	axon	axon	NOUN
fnp-5842	365	45	regeneration	regeneration	NOUN
fnp-5842	365	46	in	in	ADP
fnp-5842	365	47	vitro	vitro	X
fnp-5842	365	48	.	.	PUNCT
fnp-5842	366	1	immunocytochemistry	immunocytochemistry	NOUN
fnp-5842	366	2	was	be	AUX
fnp-5842	366	3	performed	perform	VERB
fnp-5842	366	4	to	to	PART
fnp-5842	366	5	quantify	quantify	VERB
fnp-5842	366	6	the	the	DET
fnp-5842	366	7	extent	extent	NOUN
fnp-5842	366	8	of	of	ADP
fnp-5842	366	9	sc	sc	PROPN
fnp-5842	366	10	-	-	PUNCT
fnp-5842	366	11	ac	ac	PROPN
fnp-5842	366	12	intermingling	intermingle	VERB
fnp-5842	366	13	and	and	CCONJ
fnp-5842	366	14	the	the	DET
fnp-5842	366	15	success	success	NOUN
fnp-5842	366	16	of	of	ADP
fnp-5842	366	17	axon	axon	NOUN
fnp-5842	366	18	regeneration	regeneration	NOUN
fnp-5842	366	19	across	across	ADP
fnp-5842	366	20	the	the	DET
fnp-5842	366	21	modified	modify	VERB
fnp-5842	366	22	sc	sc	PROPN
fnp-5842	366	23	-	-	PUNCT
fnp-5842	366	24	ac	ac	PROPN
fnp-5842	366	25	interface	interface	NOUN
fnp-5842	366	26	.	.	PUNCT
fnp-5842	367	1	our	our	PRON
fnp-5842	367	2	study	study	NOUN
fnp-5842	367	3	demonstrates	demonstrate	VERB
fnp-5842	367	4	the	the	DET
fnp-5842	367	5	powerful	powerful	ADJ
fnp-5842	367	6	effect	effect	NOUN
fnp-5842	367	7	of	of	ADP
fnp-5842	367	8	oriented	orient	VERB
fnp-5842	367	9	substrate	substrate	NOUN
fnp-5842	367	10	topography	topography	NOUN
fnp-5842	367	11	on	on	ADP
fnp-5842	367	12	sc	sc	PROPN
fnp-5842	367	13	-	-	PUNCT
fnp-5842	367	14	ac	ac	PROPN
fnp-5842	367	15	interactions	interaction	NOUN
fnp-5842	367	16	,	,	PUNCT
fnp-5842	367	17	preventing	prevent	VERB
fnp-5842	367	18	the	the	DET
fnp-5842	367	19	formation	formation	NOUN
fnp-5842	367	20	of	of	ADP
fnp-5842	367	21	barrier	barrier	NOUN
fnp-5842	367	22	-	-	PUNCT
fnp-5842	367	23	forming	form	VERB
fnp-5842	367	24	sc	sc	PROPN
fnp-5842	367	25	-	-	PUNCT
fnp-5842	367	26	ac	ac	PROPN
fnp-5842	367	27	interfaces	interface	NOUN
fnp-5842	367	28	and	and	CCONJ
fnp-5842	367	29	enabling	enable	VERB
fnp-5842	367	30	substantial	substantial	ADJ
fnp-5842	367	31	directed	direct	VERB
fnp-5842	367	32	and	and	CCONJ
fnp-5842	367	33	long	long	ADJ
fnp-5842	367	34	-	-	PUNCT
fnp-5842	367	35	distance	distance	NOUN
fnp-5842	367	36	axon	axon	NOUN
fnp-5842	367	37	outgrowth	outgrowth	VERB
fnp-5842	367	38	across	across	ADP
fnp-5842	367	39	the	the	DET
fnp-5842	367	40	sc	sc	PROPN
fnp-5842	367	41	-	-	PUNCT
fnp-5842	367	42	ac	ac	PROPN
fnp-5842	367	43	interface	interface	NOUN
fnp-5842	367	44	and	and	CCONJ
fnp-5842	367	45	into	into	ADP
fnp-5842	367	46	the	the	DET
fnp-5842	367	47	ac	ac	PROPN
fnp-5842	367	48	compartment	compartment	NOUN
fnp-5842	367	49	.	.	PUNCT
fnp-5842	368	1	this	this	PRON
fnp-5842	368	2	is	be	AUX
fnp-5842	368	3	the	the	DET
fnp-5842	368	4	first	first	ADJ
fnp-5842	368	5	demonstration	demonstration	NOUN
fnp-5842	368	6	of	of	ADP
fnp-5842	368	7	non	non	ADJ
fnp-5842	368	8	-	-	ADJ
fnp-5842	368	9	functionalized	functionalized	ADJ
fnp-5842	368	10	nanofibers	nanofiber	NOUN
fnp-5842	368	11	providing	provide	VERB
fnp-5842	368	12	a	a	DET
fnp-5842	368	13	substrate	substrate	NOUN
fnp-5842	368	14	that	that	PRON
fnp-5842	368	15	can	can	AUX
fnp-5842	368	16	override	override	VERB
fnp-5842	368	17	such	such	ADJ
fnp-5842	368	18	mutually	mutually	ADV
fnp-5842	368	19	repulsive	repulsive	ADJ
fnp-5842	368	20	cell	cell	NOUN
fnp-5842	368	21	-	-	PUNCT
fnp-5842	368	22	cell	cell	NOUN
fnp-5842	368	23	interactions	interaction	NOUN
fnp-5842	368	24	.	.	PUNCT
fnp-5842	369	1	it	it	PRON
fnp-5842	369	2	is	be	AUX
fnp-5842	369	3	anticipated	anticipate	VERB
fnp-5842	369	4	that	that	SCONJ
fnp-5842	369	5	these	these	DET
fnp-5842	369	6	findings	finding	NOUN
fnp-5842	369	7	will	will	AUX
fnp-5842	369	8	profoundly	profoundly	ADV
fnp-5842	369	9	influence	influence	VERB
fnp-5842	369	10	the	the	DET
fnp-5842	369	11	design	design	NOUN
fnp-5842	369	12	of	of	ADP
fnp-5842	369	13	biomaterial	biomaterial	NOUN
fnp-5842	369	14	-	-	PUNCT
fnp-5842	369	15	based	base	VERB
fnp-5842	369	16	scaffolds	scaffold	NOUN
fnp-5842	369	17	for	for	ADP
fnp-5842	369	18	spinal	spinal	ADJ
fnp-5842	369	19	cord	cord	NOUN
fnp-5842	369	20	injury	injury	NOUN
fnp-5842	369	21	repair	repair	NOUN
fnp-5842	369	22	.	.	PUNCT
fnp-5842	370	1	p30	p30	NOUN
fnp-5842	370	2	free	free	ADJ
fnp-5842	370	3	neuropathol	neuropathol	NOUN
fnp-5842	371	1	5:19:45	5:19:45	NUM
fnp-5842	371	2	using	use	VERB
fnp-5842	371	3	eye	eye	NOUN
fnp-5842	371	4	-	-	PUNCT
fnp-5842	371	5	tracking	tracking	NOUN
fnp-5842	371	6	to	to	PART
fnp-5842	371	7	find	find	VERB
fnp-5842	371	8	differences	difference	NOUN
fnp-5842	371	9	in	in	ADP
fnp-5842	371	10	the	the	DET
fnp-5842	371	11	analysis	analysis	NOUN
fnp-5842	371	12	of	of	ADP
fnp-5842	371	13	whole	whole	ADJ
fnp-5842	371	14	-	-	PUNCT
fnp-5842	371	15	slide	slide	NOUN
fnp-5842	371	16	images	image	NOUN
fnp-5842	371	17	between	between	ADP
fnp-5842	371	18	physicians	physician	NOUN
fnp-5842	371	19	and	and	CCONJ
fnp-5842	371	20	machine	machine	NOUN
fnp-5842	371	21	learning	learning	NOUN
fnp-5842	371	22	models	model	NOUN
fnp-5842	371	23	–	–	PUNCT
fnp-5842	371	24	a	a	DET
fnp-5842	371	25	study	study	NOUN
fnp-5842	371	26	design	design	NOUN
fnp-5842	371	27	daniel	daniel	PROPN
fnp-5842	371	28	hieber1,2,3,4	hieber1,2,3,4	PROPN
fnp-5842	371	29	,	,	PUNCT
fnp-5842	371	30	nicola	nicola	PROPN
fnp-5842	371	31	jungbäck1,3	jungbäck1,3	PROPN
fnp-5842	371	32	,	,	PUNCT
fnp-5842	371	33	felix	felix	PROPN
fnp-5842	371	34	holl2	holl2	PROPN
fnp-5842	371	35	,	,	PUNCT
fnp-5842	371	36	bruno	bruno	PROPN
fnp-5842	371	37	märkl3	märkl3	PROPN
fnp-5842	371	38	,	,	PUNCT
fnp-5842	371	39	rüdiger	rüdiger	ADJ
fnp-5842	371	40	pryss4	pryss4	PROPN
fnp-5842	371	41	,	,	PUNCT
fnp-5842	371	42	johannes	johanne	NOUN
fnp-5842	371	43	schobel2	schobel2	PROPN
fnp-5842	371	44	,	,	PUNCT
fnp-5842	371	45	friederike	friederike	ADJ
fnp-5842	371	46	liesche	liesche	NOUN
fnp-5842	371	47	starnecker1,3	starnecker1,3	PROPN
fnp-5842	371	48	1	1	NUM
fnp-5842	371	49	department	department	NOUN
fnp-5842	371	50	of	of	ADP
fnp-5842	371	51	neuropathology	neuropathology	NOUN
fnp-5842	371	52	,	,	PUNCT
fnp-5842	371	53	pathology	pathology	NOUN
fnp-5842	371	54	,	,	PUNCT
fnp-5842	371	55	medical	medical	ADJ
fnp-5842	371	56	faculty	faculty	NOUN
fnp-5842	371	57	,	,	PUNCT
fnp-5842	371	58	university	university	NOUN
fnp-5842	371	59	of	of	ADP
fnp-5842	371	60	augsburg	augsburg	PROPN
fnp-5842	371	61	,	,	PUNCT
fnp-5842	371	62	augsburg	augsburg	PROPN
fnp-5842	371	63	,	,	PUNCT
fnp-5842	371	64	germany	germany	PROPN
fnp-5842	371	65	2	2	NUM
fnp-5842	371	66	digihealth	digihealth	PROPN
fnp-5842	371	67	institute	institute	PROPN
fnp-5842	371	68	,	,	PUNCT
fnp-5842	371	69	neu	neu	PROPN
fnp-5842	371	70	-	-	PUNCT
fnp-5842	371	71	ulm	ulm	PROPN
fnp-5842	371	72	university	university	PROPN
fnp-5842	371	73	of	of	ADP
fnp-5842	371	74	applied	apply	VERB
fnp-5842	371	75	sciences	science	NOUN
fnp-5842	371	76	,	,	PUNCT
fnp-5842	371	77	neu	neu	PROPN
fnp-5842	371	78	-	-	PUNCT
fnp-5842	371	79	ulm	ulm	PROPN
fnp-5842	371	80	,	,	PUNCT
fnp-5842	371	81	germany	germany	PROPN
fnp-5842	371	82	3	3	NUM
fnp-5842	371	83	pathology	pathology	PROPN
fnp-5842	371	84	,	,	PUNCT
fnp-5842	371	85	medical	medical	ADJ
fnp-5842	371	86	faculty	faculty	NOUN
fnp-5842	371	87	,	,	PUNCT
fnp-5842	371	88	university	university	NOUN
fnp-5842	371	89	of	of	ADP
fnp-5842	371	90	augsburg	augsburg	PROPN
fnp-5842	371	91	,	,	PUNCT
fnp-5842	371	92	augsburg	augsburg	PROPN
fnp-5842	371	93	,	,	PUNCT
fnp-5842	371	94	germany	germany	PROPN
fnp-5842	371	95	4	4	NUM
fnp-5842	371	96	institute	institute	PROPN
fnp-5842	371	97	of	of	ADP
fnp-5842	371	98	medical	medical	ADJ
fnp-5842	371	99	data	datum	NOUN
fnp-5842	371	100	science	science	NOUN
fnp-5842	371	101	,	,	PUNCT
fnp-5842	371	102	university	university	NOUN
fnp-5842	371	103	hospital	hospital	NOUN
fnp-5842	371	104	würzburg	würzburg	PROPN
fnp-5842	371	105	,	,	PUNCT
fnp-5842	371	106	würzburg	würzburg	PROPN
fnp-5842	371	107	,	,	PUNCT
fnp-5842	371	108	germany	germany	PROPN
fnp-5842	371	109	neuropathologists	neuropathologist	NOUN
fnp-5842	371	110	are	be	AUX
fnp-5842	371	111	experts	expert	NOUN
fnp-5842	371	112	in	in	ADP
fnp-5842	371	113	their	their	PRON
fnp-5842	371	114	field	field	NOUN
fnp-5842	371	115	,	,	PUNCT
fnp-5842	371	116	quickly	quickly	ADV
fnp-5842	371	117	detecting	detect	VERB
fnp-5842	371	118	and	and	CCONJ
fnp-5842	371	119	classifying	classify	VERB
fnp-5842	371	120	tumors	tumor	NOUN
fnp-5842	371	121	in	in	ADP
fnp-5842	371	122	whole	whole	ADJ
fnp-5842	371	123	-	-	PUNCT
fnp-5842	371	124	slide	slide	NOUN
fnp-5842	371	125	images	image	NOUN
fnp-5842	371	126	(	(	PUNCT
fnp-5842	371	127	wsis	wsis	NOUN
fnp-5842	371	128	)	)	PUNCT
fnp-5842	371	129	.	.	PUNCT
fnp-5842	372	1	however	however	ADV
fnp-5842	372	2	,	,	PUNCT
fnp-5842	372	3	it	it	PRON
fnp-5842	372	4	is	be	AUX
fnp-5842	372	5	often	often	ADV
fnp-5842	372	6	unclear	unclear	ADJ
fnp-5842	372	7	what	what	PRON
fnp-5842	372	8	features	feature	VERB
fnp-5842	372	9	they	they	PRON
fnp-5842	372	10	focus	focus	VERB
fnp-5842	372	11	on	on	ADP
fnp-5842	372	12	and	and	CCONJ
fnp-5842	372	13	which	which	DET
fnp-5842	372	14	aspects	aspect	VERB
fnp-5842	372	15	they	they	PRON
fnp-5842	372	16	rely	rely	VERB
fnp-5842	372	17	on	on	ADP
fnp-5842	372	18	for	for	ADP
fnp-5842	372	19	their	their	PRON
fnp-5842	372	20	decision	decision	NOUN
fnp-5842	372	21	.	.	PUNCT
fnp-5842	373	1	machine	machine	NOUN
fnp-5842	373	2	learning	learning	NOUN
fnp-5842	373	3	(	(	PUNCT
fnp-5842	373	4	ml	ml	NOUN
fnp-5842	373	5	)	)	PUNCT
fnp-5842	373	6	is	be	AUX
fnp-5842	373	7	also	also	ADV
fnp-5842	373	8	increasingly	increasingly	ADV
fnp-5842	373	9	used	use	VERB
fnp-5842	373	10	in	in	ADP
fnp-5842	373	11	pathology	pathology	NOUN
fnp-5842	373	12	,	,	PUNCT
fnp-5842	373	13	but	but	CCONJ
fnp-5842	373	14	its	its	PRON
fnp-5842	373	15	decision	decision	NOUN
fnp-5842	373	16	-	-	PUNCT
fnp-5842	373	17	making	make	VERB
fnp-5842	373	18	process	process	NOUN
fnp-5842	373	19	is	be	AUX
fnp-5842	373	20	similarly	similarly	ADV
fnp-5842	373	21	opaque	opaque	ADJ
fnp-5842	373	22	.	.	PUNCT
fnp-5842	374	1	to	to	PART
fnp-5842	374	2	better	well	ADV
fnp-5842	374	3	understand	understand	VERB
fnp-5842	374	4	expert	expert	ADJ
fnp-5842	374	5	analysis	analysis	NOUN
fnp-5842	374	6	and	and	CCONJ
fnp-5842	374	7	evaluate	evaluate	VERB
fnp-5842	374	8	ml	ml	NOUN
fnp-5842	374	9	reasoning	reasoning	NOUN
fnp-5842	374	10	,	,	PUNCT
fnp-5842	374	11	an	an	DET
fnp-5842	374	12	eye	eye	NOUN
fnp-5842	374	13	-	-	PUNCT
fnp-5842	374	14	tracking	track	VERB
fnp-5842	374	15	study	study	NOUN
fnp-5842	374	16	will	will	AUX
fnp-5842	374	17	compare	compare	VERB
fnp-5842	374	18	detection	detection	NOUN
fnp-5842	374	19	accuracy	accuracy	NOUN
fnp-5842	374	20	and	and	CCONJ
fnp-5842	374	21	region	region	NOUN
fnp-5842	374	22	of	of	ADP
fnp-5842	374	23	interest	interest	NOUN
fnp-5842	374	24	(	(	PUNCT
fnp-5842	374	25	roi	roi	NOUN
fnp-5842	374	26	)	)	PUNCT
fnp-5842	374	27	selection	selection	NOUN
fnp-5842	374	28	among	among	ADP
fnp-5842	374	29	neuropathologists	neuropathologist	NOUN
fnp-5842	374	30	,	,	PUNCT
fnp-5842	374	31	pathologists	pathologist	NOUN
fnp-5842	374	32	in	in	ADP
fnp-5842	374	33	general	general	ADJ
fnp-5842	374	34	,	,	PUNCT
fnp-5842	374	35	medical	medical	ADJ
fnp-5842	374	36	students	student	NOUN
fnp-5842	374	37	,	,	PUNCT
fnp-5842	374	38	and	and	CCONJ
fnp-5842	374	39	ml	ml	ADP
fnp-5842	374	40	models	model	NOUN
fnp-5842	374	41	.	.	PUNCT
fnp-5842	375	1	the	the	DET
fnp-5842	375	2	study	study	NOUN
fnp-5842	375	3	involves	involve	VERB
fnp-5842	375	4	experts	expert	NOUN
fnp-5842	375	5	(	(	PUNCT
fnp-5842	375	6	neuropathologists	neuropathologist	NOUN
fnp-5842	375	7	and	and	CCONJ
fnp-5842	375	8	pathologists	pathologist	NOUN
fnp-5842	375	9	with	with	ADP
fnp-5842	375	10	high	high	ADJ
fnp-5842	375	11	experience	experience	NOUN
fnp-5842	375	12	in	in	ADP
fnp-5842	375	13	brain	brain	NOUN
fnp-5842	375	14	tumor	tumor	NOUN
fnp-5842	375	15	diagnostics	diagnostic	NOUN
fnp-5842	375	16	)	)	PUNCT
fnp-5842	375	17	,	,	PUNCT
fnp-5842	375	18	intermediates	intermediate	NOUN
fnp-5842	375	19	(	(	PUNCT
fnp-5842	375	20	pathologists	pathologist	NOUN
fnp-5842	375	21	without	without	ADP
fnp-5842	375	22	any	any	DET
fnp-5842	375	23	particular	particular	ADJ
fnp-5842	375	24	expertise	expertise	NOUN
fnp-5842	375	25	in	in	ADP
fnp-5842	375	26	brain	brain	NOUN
fnp-5842	375	27	tumor	tumor	NOUN
fnp-5842	375	28	diagnosis	diagnosis	NOUN
fnp-5842	375	29	)	)	PUNCT
fnp-5842	375	30	,	,	PUNCT
fnp-5842	375	31	and	and	CCONJ
fnp-5842	375	32	beginners	beginner	NOUN
fnp-5842	375	33	(	(	PUNCT
fnp-5842	375	34	students	student	NOUN
fnp-5842	375	35	,	,	PUNCT
fnp-5842	375	36	physicians	physician	NOUN
fnp-5842	375	37	from	from	ADP
fnp-5842	375	38	other	other	ADJ
fnp-5842	375	39	domains	domain	NOUN
fnp-5842	375	40	)	)	PUNCT
fnp-5842	375	41	analyzing	analyze	VERB
fnp-5842	375	42	hematoxylin	hematoxylin	NOUN
fnp-5842	375	43	-	-	PUNCT
fnp-5842	375	44	and	and	CCONJ
fnp-5842	375	45	-	-	PUNCT
fnp-5842	375	46	eosin	eosin	NOUN
fnp-5842	375	47	(	(	PUNCT
fnp-5842	375	48	he	he	PRON
fnp-5842	375	49	)	)	PUNCT
fnp-5842	375	50	stained	stain	VERB
fnp-5842	375	51	sections	section	NOUN
fnp-5842	375	52	of	of	ADP
fnp-5842	375	53	50	50	NUM
fnp-5842	375	54	glioblastoma	glioblastoma	NOUN
fnp-5842	375	55	(	(	PUNCT
fnp-5842	375	56	gbm	gbm	NOUN
fnp-5842	375	57	)	)	PUNCT
fnp-5842	375	58	wsis	wsis	NOUN
fnp-5842	375	59	.	.	PUNCT
fnp-5842	376	1	participants	participant	NOUN
fnp-5842	376	2	must	must	AUX
fnp-5842	376	3	determine	determine	VERB
fnp-5842	376	4	whether	whether	SCONJ
fnp-5842	376	5	neoplastic	neoplastic	ADJ
fnp-5842	376	6	tissue	tissue	NOUN
fnp-5842	376	7	is	be	AUX
fnp-5842	376	8	present	present	ADJ
fnp-5842	376	9	in	in	ADP
fnp-5842	376	10	the	the	DET
fnp-5842	376	11	section	section	NOUN
fnp-5842	376	12	and	and	CCONJ
fnp-5842	376	13	,	,	PUNCT
fnp-5842	376	14	if	if	SCONJ
fnp-5842	376	15	so	so	ADV
fnp-5842	376	16	,	,	PUNCT
fnp-5842	376	17	mark	mark	VERB
fnp-5842	376	18	the	the	DET
fnp-5842	376	19	most	most	ADV
fnp-5842	376	20	relevant	relevant	ADJ
fnp-5842	376	21	regions	region	NOUN
fnp-5842	376	22	for	for	ADP
fnp-5842	376	23	their	their	PRON
fnp-5842	376	24	analysis	analysis	NOUN
fnp-5842	376	25	.	.	PUNCT
fnp-5842	377	1	the	the	DET
fnp-5842	377	2	eyelogic	eyelogic	ADJ
fnp-5842	377	3	logicone	logicone	NOUN
fnp-5842	377	4	eye	eye	NOUN
fnp-5842	377	5	-	-	PUNCT
fnp-5842	377	6	tracking	track	VERB
fnp-5842	377	7	device	device	NOUN
fnp-5842	377	8	records	record	VERB
fnp-5842	377	9	their	their	PRON
fnp-5842	377	10	gaze	gaze	NOUN
fnp-5842	377	11	during	during	ADP
fnp-5842	377	12	this	this	DET
fnp-5842	377	13	process	process	NOUN
fnp-5842	377	14	.	.	PUNCT
fnp-5842	378	1	post	post	ADJ
fnp-5842	378	2	-	-	ADJ
fnp-5842	378	3	study	study	ADJ
fnp-5842	378	4	,	,	PUNCT
fnp-5842	378	5	gaze	gaze	NOUN
fnp-5842	378	6	data	datum	NOUN
fnp-5842	378	7	from	from	ADP
fnp-5842	378	8	different	different	ADJ
fnp-5842	378	9	participant	participant	ADJ
fnp-5842	378	10	groups	group	NOUN
fnp-5842	378	11	will	will	AUX
fnp-5842	378	12	be	be	AUX
fnp-5842	378	13	compared	compare	VERB
fnp-5842	378	14	with	with	ADP
fnp-5842	378	15	ml	ml	NOUN
fnp-5842	378	16	probability	probability	NOUN
fnp-5842	378	17	masks	mask	NOUN
fnp-5842	378	18	to	to	PART
fnp-5842	378	19	identify	identify	VERB
fnp-5842	378	20	differences	difference	NOUN
fnp-5842	378	21	and	and	CCONJ
fnp-5842	378	22	similarities	similarity	NOUN
fnp-5842	378	23	between	between	ADP
fnp-5842	378	24	human	human	ADJ
fnp-5842	378	25	and	and	CCONJ
fnp-5842	378	26	artificial	artificial	ADJ
fnp-5842	378	27	analysts	analyst	NOUN
fnp-5842	378	28	.	.	PUNCT
fnp-5842	379	1	the	the	DET
fnp-5842	379	2	study	study	NOUN
fnp-5842	379	3	will	will	AUX
fnp-5842	379	4	also	also	ADV
fnp-5842	379	5	correlate	correlate	VERB
fnp-5842	379	6	selected	select	VERB
fnp-5842	379	7	rois	rois	NOUN
fnp-5842	379	8	with	with	ADP
fnp-5842	379	9	ml	ml	NOUN
fnp-5842	379	10	probabilities	probability	NOUN
fnp-5842	379	11	and	and	CCONJ
fnp-5842	379	12	gaze	gaze	VERB
fnp-5842	379	13	duration	duration	NOUN
fnp-5842	379	14	to	to	PART
fnp-5842	379	15	see	see	VERB
fnp-5842	379	16	if	if	SCONJ
fnp-5842	379	17	the	the	DET
fnp-5842	379	18	most	most	ADV
fnp-5842	379	19	critical	critical	ADJ
fnp-5842	379	20	areas	area	NOUN
fnp-5842	379	21	are	be	AUX
fnp-5842	379	22	those	those	PRON
fnp-5842	379	23	most	most	ADV
fnp-5842	379	24	viewed	view	VERB
fnp-5842	379	25	by	by	ADP
fnp-5842	379	26	humans	human	NOUN
fnp-5842	379	27	and	and	CCONJ
fnp-5842	379	28	deemed	deem	VERB
fnp-5842	379	29	most	most	ADV
fnp-5842	379	30	important	important	ADJ
fnp-5842	379	31	by	by	ADP
fnp-5842	379	32	ml	ml	NOUN
fnp-5842	379	33	.	.	PUNCT
fnp-5842	380	1	an	an	DET
fnp-5842	380	2	eye	eye	NOUN
fnp-5842	380	3	-	-	PUNCT
fnp-5842	380	4	tracking	track	VERB
fnp-5842	380	5	study	study	NOUN
fnp-5842	380	6	is	be	AUX
fnp-5842	380	7	planned	plan	VERB
fnp-5842	380	8	for	for	ADP
fnp-5842	380	9	october	october	PROPN
fnp-5842	380	10	2024	2024	NUM
fnp-5842	380	11	,	,	PUNCT
fnp-5842	380	12	comparing	compare	VERB
fnp-5842	380	13	the	the	DET
fnp-5842	380	14	analysis	analysis	NOUN
fnp-5842	380	15	of	of	ADP
fnp-5842	380	16	he	he	PRON
fnp-5842	380	17	-	-	PUNCT
fnp-5842	380	18	stained	stain	VERB
fnp-5842	380	19	wsis	wsis	NOUN
fnp-5842	380	20	of	of	ADP
fnp-5842	380	21	gbms	gbms	NOUN
fnp-5842	380	22	between	between	ADP
fnp-5842	380	23	human	human	ADJ
fnp-5842	380	24	analysts	analyst	NOUN
fnp-5842	380	25	and	and	CCONJ
fnp-5842	380	26	ml	ml	NOUN
fnp-5842	380	27	models	model	NOUN
fnp-5842	380	28	.	.	PUNCT
fnp-5842	381	1	the	the	DET
fnp-5842	381	2	study	study	NOUN
fnp-5842	381	3	is	be	AUX
fnp-5842	381	4	currently	currently	ADV
fnp-5842	381	5	in	in	ADP
fnp-5842	381	6	the	the	DET
fnp-5842	381	7	recruitment	recruitment	NOUN
fnp-5842	381	8	phase	phase	NOUN
fnp-5842	381	9	,	,	PUNCT
fnp-5842	381	10	with	with	ADP
fnp-5842	381	11	results	result	NOUN
fnp-5842	381	12	expected	expect	VERB
fnp-5842	381	13	by	by	ADP
fnp-5842	381	14	end	end	NOUN
fnp-5842	381	15	of	of	ADP
fnp-5842	381	16	the	the	DET
fnp-5842	381	17	year	year	NOUN
fnp-5842	381	18	.	.	PUNCT
fnp-5842	382	1	p31	p31	PROPN
fnp-5842	382	2	free	free	ADJ
fnp-5842	382	3	neuropathol	neuropathol	NOUN
fnp-5842	382	4	5:19:46	5:19:46	NUM
fnp-5842	382	5	why	why	SCONJ
fnp-5842	382	6	we	we	PRON
fnp-5842	382	7	do	do	AUX
fnp-5842	382	8	n’t	not	PART
fnp-5842	382	9	save	save	VERB
fnp-5842	382	10	whole	whole	ADJ
fnp-5842	382	11	-	-	PUNCT
fnp-5842	382	12	slide	slide	NOUN
fnp-5842	382	13	images	image	NOUN
fnp-5842	382	14	as	as	ADP
fnp-5842	382	15	lego	lego	NOUN
fnp-5842	382	16	mosaics	mosaic	NOUN
fnp-5842	382	17	–	–	PUNCT
fnp-5842	382	18	putting	put	VERB
fnp-5842	382	19	the	the	DET
fnp-5842	382	20	scale	scale	NOUN
fnp-5842	382	21	of	of	ADP
fnp-5842	382	22	whole	whole	ADJ
fnp-5842	382	23	-	-	PUNCT
fnp-5842	382	24	slide	slide	NOUN
fnp-5842	382	25	images	image	NOUN
fnp-5842	382	26	into	into	ADP
fnp-5842	382	27	perspective	perspective	NOUN
fnp-5842	382	28	daniel	daniel	PROPN
fnp-5842	382	29	hieber1,2,3	hieber1,2,3	PROPN
fnp-5842	382	30	,	,	PUNCT
fnp-5842	382	31	nicola	nicola	PROPN
fnp-5842	382	32	jungbäck1	jungbäck1	PROPN
fnp-5842	382	33	,	,	PUNCT
fnp-5842	382	34	felix	felix	PROPN
fnp-5842	382	35	holl2	holl2	PROPN
fnp-5842	382	36	,	,	PUNCT
fnp-5842	382	37	bruno	bruno	PROPN
fnp-5842	382	38	märkl4	märkl4	PROPN
fnp-5842	382	39	,	,	PUNCT
fnp-5842	382	40	rüdiger	rüdiger	ADJ
fnp-5842	382	41	pryss3	pryss3	PROPN
fnp-5842	382	42	,	,	PUNCT
fnp-5842	382	43	johannes	johanne	NOUN
fnp-5842	382	44	schobel2	schobel2	NOUN
fnp-5842	382	45	,	,	PUNCT
fnp-5842	382	46	friederike	friederike	ADJ
fnp-5842	382	47	liesche	liesche	NOUN
fnp-5842	382	48	starnecker1	starnecker1	NOUN
fnp-5842	382	49	1	1	NUM
fnp-5842	382	50	department	department	NOUN
fnp-5842	382	51	of	of	ADP
fnp-5842	382	52	neuropathology	neuropathology	NOUN
fnp-5842	382	53	,	,	PUNCT
fnp-5842	382	54	pathology	pathology	NOUN
fnp-5842	382	55	,	,	PUNCT
fnp-5842	382	56	medical	medical	ADJ
fnp-5842	382	57	faculty	faculty	NOUN
fnp-5842	382	58	,	,	PUNCT
fnp-5842	382	59	university	university	NOUN
fnp-5842	382	60	of	of	ADP
fnp-5842	382	61	augsburg	augsburg	PROPN
fnp-5842	382	62	,	,	PUNCT
fnp-5842	382	63	augsburg	augsburg	PROPN
fnp-5842	382	64	,	,	PUNCT
fnp-5842	382	65	germany	germany	PROPN
fnp-5842	382	66	2	2	NUM
fnp-5842	382	67	digihealth	digihealth	PROPN
fnp-5842	382	68	institute	institute	PROPN
fnp-5842	382	69	,	,	PUNCT
fnp-5842	382	70	neu	neu	PROPN
fnp-5842	382	71	-	-	PUNCT
fnp-5842	382	72	ulm	ulm	PROPN
fnp-5842	382	73	university	university	PROPN
fnp-5842	382	74	of	of	ADP
fnp-5842	382	75	applied	apply	VERB
fnp-5842	382	76	sciences	science	NOUN
fnp-5842	382	77	,	,	PUNCT
fnp-5842	382	78	neu	neu	PROPN
fnp-5842	382	79	-	-	PUNCT
fnp-5842	382	80	ulm	ulm	PROPN
fnp-5842	382	81	,	,	PUNCT
fnp-5842	382	82	germany	germany	PROPN
fnp-5842	382	83	3	3	NUM
fnp-5842	382	84	institute	institute	PROPN
fnp-5842	382	85	of	of	ADP
fnp-5842	382	86	medical	medical	ADJ
fnp-5842	382	87	data	datum	NOUN
fnp-5842	382	88	science	science	NOUN
fnp-5842	382	89	,	,	PUNCT
fnp-5842	382	90	university	university	NOUN
fnp-5842	382	91	hospital	hospital	NOUN
fnp-5842	382	92	würzburg	würzburg	PROPN
fnp-5842	382	93	,	,	PUNCT
fnp-5842	382	94	würzburg	würzburg	PROPN
fnp-5842	382	95	,	,	PUNCT
fnp-5842	382	96	germany	germany	PROPN
fnp-5842	382	97	4	4	NUM
fnp-5842	382	98	pathology	pathology	NOUN
fnp-5842	382	99	,	,	PUNCT
fnp-5842	382	100	medical	medical	ADJ
fnp-5842	382	101	faculty	faculty	NOUN
fnp-5842	382	102	,	,	PUNCT
fnp-5842	382	103	university	university	NOUN
fnp-5842	382	104	of	of	ADP
fnp-5842	382	105	augsburg	augsburg	PROPN
fnp-5842	382	106	,	,	PUNCT
fnp-5842	382	107	augsburg	augsburg	PROPN
fnp-5842	382	108	,	,	PUNCT
fnp-5842	382	109	germany	germany	PROPN
fnp-5842	382	110	why	why	SCONJ
fnp-5842	382	111	do	do	AUX
fnp-5842	382	112	we	we	PRON
fnp-5842	382	113	save	save	VERB
fnp-5842	382	114	whole	whole	ADJ
fnp-5842	382	115	-	-	PUNCT
fnp-5842	382	116	slide	slide	NOUN
fnp-5842	382	117	images	image	NOUN
fnp-5842	382	118	(	(	PUNCT
fnp-5842	382	119	wsis	wsis	NOUN
fnp-5842	382	120	)	)	PUNCT
fnp-5842	382	121	as	as	SCONJ
fnp-5842	382	122	dicom	dicom	NOUN
fnp-5842	382	123	-	-	PUNCT
fnp-5842	382	124	wsi	wsi	PROPN
fnp-5842	382	125	,	,	PUNCT
fnp-5842	382	126	tiff	tiff	NOUN
fnp-5842	382	127	,	,	PUNCT
fnp-5842	382	128	svs	svs	NOUN
fnp-5842	382	129	,	,	PUNCT
fnp-5842	382	130	...	...	PUNCT
fnp-5842	382	131	and	and	CCONJ
fnp-5842	382	132	not	not	PART
fnp-5842	382	133	as	as	ADP
fnp-5842	382	134	lego	lego	NOUN
fnp-5842	382	135	mosaics	mosaic	NOUN
fnp-5842	382	136	?	?	PUNCT
fnp-5842	383	1	while	while	SCONJ
fnp-5842	383	2	the	the	DET
fnp-5842	383	3	answer	answer	NOUN
fnp-5842	383	4	to	to	ADP
fnp-5842	383	5	this	this	DET
fnp-5842	383	6	question	question	NOUN
fnp-5842	383	7	might	might	AUX
fnp-5842	383	8	be	be	AUX
fnp-5842	383	9	pretty	pretty	ADV
fnp-5842	383	10	obvious	obvious	ADJ
fnp-5842	383	11	(	(	PUNCT
fnp-5842	383	12	working	work	VERB
fnp-5842	383	13	with	with	ADP
fnp-5842	383	14	digital	digital	ADJ
fnp-5842	383	15	data	datum	NOUN
fnp-5842	383	16	is	be	AUX
fnp-5842	383	17	much	much	ADV
fnp-5842	383	18	easier	easy	ADJ
fnp-5842	383	19	,	,	PUNCT
fnp-5842	383	20	and	and	CCONJ
fnp-5842	383	21	the	the	DET
fnp-5842	383	22	staining	stain	VERB
fnp-5842	383	23	is	be	AUX
fnp-5842	383	24	closer	close	ADJ
fnp-5842	383	25	to	to	ADP
fnp-5842	383	26	the	the	DET
fnp-5842	383	27	original	original	NOUN
fnp-5842	383	28	)	)	PUNCT
fnp-5842	383	29	,	,	PUNCT
fnp-5842	383	30	we	we	PRON
fnp-5842	383	31	want	want	VERB
fnp-5842	383	32	to	to	PART
fnp-5842	383	33	use	use	VERB
fnp-5842	383	34	the	the	DET
fnp-5842	383	35	latter	latter	ADJ
fnp-5842	383	36	to	to	PART
fnp-5842	383	37	put	put	VERB
fnp-5842	383	38	the	the	DET
fnp-5842	383	39	scale	scale	NOUN
fnp-5842	383	40	of	of	ADP
fnp-5842	383	41	wsis	wsis	NOUN
fnp-5842	383	42	into	into	ADP
fnp-5842	383	43	perspective	perspective	NOUN
fnp-5842	383	44	.	.	PUNCT
fnp-5842	384	1	wsis	wsis	NOUN
fnp-5842	384	2	typically	typically	ADV
fnp-5842	384	3	scale	scale	VERB
fnp-5842	384	4	up	up	ADP
fnp-5842	384	5	to	to	PART
fnp-5842	384	6	80,000	80,000	NUM
fnp-5842	384	7	x	x	SYM
fnp-5842	384	8	60,000	60,000	NUM
fnp-5842	384	9	pixels	pixel	NOUN
fnp-5842	384	10	(	(	PUNCT
fnp-5842	384	11	larger	large	ADJ
fnp-5842	384	12	sizes	size	NOUN
fnp-5842	384	13	are	be	AUX
fnp-5842	384	14	possible	possible	ADJ
fnp-5842	384	15	)	)	PUNCT
fnp-5842	384	16	.	.	PUNCT
fnp-5842	385	1	when	when	SCONJ
fnp-5842	385	2	transforming	transform	VERB
fnp-5842	385	3	such	such	ADJ
fnp-5842	385	4	images	image	NOUN
fnp-5842	385	5	into	into	ADP
fnp-5842	385	6	lego	lego	NOUN
fnp-5842	385	7	,	,	PUNCT
fnp-5842	385	8	we	we	PRON
fnp-5842	385	9	need	need	VERB
fnp-5842	385	10	4.8	4.8	NUM
fnp-5842	385	11	billion	billion	NUM
fnp-5842	385	12	1	1	NUM
fnp-5842	385	13	 	 	SPACE
fnp-5842	385	14	x	x	SYM
fnp-5842	385	15	 	 	SPACE
fnp-5842	385	16	1	1	NUM
fnp-5842	385	17	lego	lego	NOUN
fnp-5842	385	18	plates	plate	NOUN
fnp-5842	385	19	and	and	CCONJ
fnp-5842	385	20	4,687,500	4,687,500	NUM
fnp-5842	385	21	32	32	NUM
fnp-5842	385	22	 	 	SPACE
fnp-5842	385	23	x	x	SYM
fnp-5842	385	24	 	 	SPACE
fnp-5842	385	25	32	32	NUM
fnp-5842	385	26	lego	lego	NOUN
fnp-5842	385	27	base	base	NOUN
fnp-5842	385	28	plates	plate	NOUN
fnp-5842	385	29	.	.	PUNCT
fnp-5842	386	1	this	this	PRON
fnp-5842	386	2	would	would	AUX
fnp-5842	386	3	accumulate	accumulate	VERB
fnp-5842	386	4	to	to	ADP
fnp-5842	386	5	a	a	DET
fnp-5842	386	6	total	total	ADJ
fnp-5842	386	7	cost	cost	NOUN
fnp-5842	386	8	of	of	ADP
fnp-5842	386	9	330	330	NUM
fnp-5842	386	10	million	million	NUM
fnp-5842	386	11	euros	euro	NOUN
fnp-5842	386	12	for	for	ADP
fnp-5842	386	13	a	a	DET
fnp-5842	386	14	single	single	ADJ
fnp-5842	386	15	wsi	wsi	NOUN
fnp-5842	386	16	using	use	VERB
fnp-5842	386	17	original	original	ADJ
fnp-5842	386	18	lego	lego	NOUN
fnp-5842	386	19	blocks	block	NOUN
fnp-5842	386	20	.	.	PUNCT
fnp-5842	387	1	the	the	DET
fnp-5842	387	2	final	final	ADJ
fnp-5842	387	3	mosaic	mosaic	NOUN
fnp-5842	387	4	would	would	AUX
fnp-5842	387	5	result	result	VERB
fnp-5842	387	6	in	in	ADP
fnp-5842	387	7	a	a	DET
fnp-5842	387	8	size	size	NOUN
fnp-5842	387	9	of	of	ADP
fnp-5842	387	10	625	625	NUM
fnp-5842	387	11	 	 	SPACE
fnp-5842	387	12	m	m	NOUN
fnp-5842	387	13	by	by	ADP
fnp-5842	387	14	468.75	468.75	NUM
fnp-5842	387	15	 	 	SPACE
fnp-5842	387	16	m	m	PROPN
fnp-5842	387	17	,	,	PUNCT
fnp-5842	387	18	a	a	DET
fnp-5842	387	19	total	total	ADJ
fnp-5842	387	20	area	area	NOUN
fnp-5842	387	21	of	of	ADP
fnp-5842	387	22	292,968.75	292,968.75	NUM
fnp-5842	387	23	 	 	SPACE
fnp-5842	387	24	m2	m2	PROPN
fnp-5842	387	25	(	(	PUNCT
fnp-5842	387	26	41.03	41.03	NUM
fnp-5842	387	27	soccer	soccer	NOUN
fnp-5842	387	28	fields	field	NOUN
fnp-5842	387	29	or	or	CCONJ
fnp-5842	387	30	approx	approx	NOUN
fnp-5842	387	31	.	.	PUNCT
fnp-5842	388	1	2.09	2.09	NUM
fnp-5842	388	2	times	time	NOUN
fnp-5842	388	3	legoland	legoland	PROPN
fnp-5842	388	4	germany	germany	PROPN
fnp-5842	388	5	)	)	PUNCT
fnp-5842	388	6	.	.	PUNCT
fnp-5842	389	1	since	since	SCONJ
fnp-5842	389	2	lego	lego	NOUN
fnp-5842	389	3	currently	currently	ADV
fnp-5842	389	4	offers	offer	VERB
fnp-5842	389	5	only	only	ADV
fnp-5842	389	6	40	40	NUM
fnp-5842	389	7	different	different	ADJ
fnp-5842	389	8	colors	color	NOUN
fnp-5842	389	9	for	for	ADP
fnp-5842	389	10	its	its	PRON
fnp-5842	389	11	plates	plate	NOUN
fnp-5842	389	12	–	–	PUNCT
fnp-5842	389	13	of	of	ADP
fnp-5842	389	14	which	which	PRON
fnp-5842	389	15	only	only	ADV
fnp-5842	389	16	about	about	ADV
fnp-5842	389	17	10	10	NUM
fnp-5842	389	18	to	to	PART
fnp-5842	389	19	20	20	NUM
fnp-5842	389	20	are	be	AUX
fnp-5842	389	21	relevant	relevant	ADJ
fnp-5842	389	22	for	for	ADP
fnp-5842	389	23	pathology	pathology	NOUN
fnp-5842	389	24	(	(	PUNCT
fnp-5842	389	25	depending	depend	VERB
fnp-5842	389	26	on	on	ADP
fnp-5842	389	27	the	the	DET
fnp-5842	389	28	staining	stain	VERB
fnp-5842	389	29	method	method	NOUN
fnp-5842	389	30	)	)	PUNCT
fnp-5842	389	31	–	–	PUNCT
fnp-5842	389	32	the	the	DET
fnp-5842	389	33	conversion	conversion	NOUN
fnp-5842	389	34	to	to	ADP
fnp-5842	389	35	a	a	DET
fnp-5842	389	36	lego	lego	NOUN
fnp-5842	389	37	mosaic	mosaic	NOUN
fnp-5842	389	38	would	would	AUX
fnp-5842	389	39	result	result	VERB
fnp-5842	389	40	in	in	ADP
fnp-5842	389	41	a	a	DET
fnp-5842	389	42	significant	significant	ADJ
fnp-5842	389	43	loss	loss	NOUN
fnp-5842	389	44	of	of	ADP
fnp-5842	389	45	information	information	NOUN
fnp-5842	389	46	.	.	PUNCT
fnp-5842	390	1	while	while	SCONJ
fnp-5842	390	2	these	these	DET
fnp-5842	390	3	numbers	number	NOUN
fnp-5842	390	4	may	may	AUX
fnp-5842	390	5	seem	seem	VERB
fnp-5842	390	6	absurdly	absurdly	ADV
fnp-5842	390	7	large	large	ADJ
fnp-5842	390	8	,	,	PUNCT
fnp-5842	390	9	processing	process	VERB
fnp-5842	390	10	a	a	DET
fnp-5842	390	11	digital	digital	ADJ
fnp-5842	390	12	wsi	wsi	NOUN
fnp-5842	390	13	with	with	ADP
fnp-5842	390	14	all	all	DET
fnp-5842	390	15	its	its	PRON
fnp-5842	390	16	information	information	NOUN
fnp-5842	390	17	at	at	ADP
fnp-5842	390	18	once	once	ADV
fnp-5842	390	19	using	use	VERB
fnp-5842	390	20	a	a	DET
fnp-5842	390	21	machine	machine	NOUN
fnp-5842	390	22	learning	learning	NOUN
fnp-5842	390	23	model	model	NOUN
fnp-5842	390	24	would	would	AUX
fnp-5842	390	25	result	result	VERB
fnp-5842	390	26	in	in	ADP
fnp-5842	390	27	14.4	14.4	NUM
fnp-5842	390	28	billion	billion	NUM
fnp-5842	390	29	input	input	NOUN
fnp-5842	390	30	parameters	parameter	NOUN
fnp-5842	390	31	.	.	PUNCT
fnp-5842	391	1	while	while	SCONJ
fnp-5842	391	2	converting	convert	VERB
fnp-5842	391	3	a	a	DET
fnp-5842	391	4	wsi	wsi	NOUN
fnp-5842	391	5	to	to	ADP
fnp-5842	391	6	lego	lego	NOUN
fnp-5842	391	7	does	do	AUX
fnp-5842	391	8	not	not	PART
fnp-5842	391	9	make	make	VERB
fnp-5842	391	10	sense	sense	NOUN
fnp-5842	391	11	from	from	ADP
fnp-5842	391	12	a	a	DET
fnp-5842	391	13	practical	practical	ADJ
fnp-5842	391	14	view	view	NOUN
fnp-5842	391	15	point	point	NOUN
fnp-5842	391	16	,	,	PUNCT
fnp-5842	391	17	it	it	PRON
fnp-5842	391	18	illustrates	illustrate	VERB
fnp-5842	391	19	the	the	DET
fnp-5842	391	20	enormous	enormous	ADJ
fnp-5842	391	21	amount	amount	NOUN
fnp-5842	391	22	of	of	ADP
fnp-5842	391	23	data	datum	NOUN
fnp-5842	391	24	in	in	ADP
fnp-5842	391	25	such	such	ADJ
fnp-5842	391	26	images	image	NOUN
fnp-5842	391	27	.	.	PUNCT
fnp-5842	392	1	these	these	DET
fnp-5842	392	2	numbers	number	NOUN
fnp-5842	392	3	further	far	ADV
fnp-5842	392	4	demonstrate	demonstrate	VERB
fnp-5842	392	5	the	the	DET
fnp-5842	392	6	immense	immense	ADJ
fnp-5842	392	7	value	value	NOUN
fnp-5842	392	8	of	of	ADP
fnp-5842	392	9	digital	digital	ADJ
fnp-5842	392	10	pathology	pathology	NOUN
fnp-5842	392	11	,	,	PUNCT
fnp-5842	392	12	allowing	allow	VERB
fnp-5842	392	13	computers	computer	NOUN
fnp-5842	392	14	to	to	PART
fnp-5842	392	15	process	process	VERB
fnp-5842	392	16	such	such	ADJ
fnp-5842	392	17	data	datum	NOUN
fnp-5842	392	18	quantities	quantity	NOUN
fnp-5842	392	19	for	for	ADP
fnp-5842	392	20	diagnostic	diagnostic	ADJ
fnp-5842	392	21	uses	use	NOUN
fnp-5842	392	22	.	.	PUNCT
fnp-5842	393	1	copyright	copyright	NOUN
fnp-5842	393	2	:	:	PUNCT
fnp-5842	393	3	©	©	PROPN
fnp-5842	393	4	2024	2024	NUM
fnp-5842	393	5	the	the	DET
fnp-5842	393	6	author(s	author(s	NOUN
fnp-5842	393	7	)	)	PUNCT
fnp-5842	393	8	.	.	PUNCT
fnp-5842	394	1	this	this	PRON
fnp-5842	394	2	is	be	AUX
fnp-5842	394	3	an	an	DET
fnp-5842	394	4	open	open	ADJ
fnp-5842	394	5	access	access	NOUN
fnp-5842	394	6	article	article	NOUN
fnp-5842	394	7	distributed	distribute	VERB
fnp-5842	394	8	under	under	ADP
fnp-5842	394	9	the	the	DET
fnp-5842	394	10	terms	term	NOUN
fnp-5842	394	11	of	of	ADP
fnp-5842	394	12	the	the	DET
fnp-5842	394	13	creative	creative	ADJ
fnp-5842	394	14	commons	common	NOUN
fnp-5842	394	15	attribution	attribution	NOUN
fnp-5842	394	16	4.0	4.0	NUM
fnp-5842	394	17	international	international	ADJ
fnp-5842	394	18	license	license	NOUN
fnp-5842	394	19	(	(	PUNCT
fnp-5842	394	20	https://creativecommons.org/licenses/by/4.0/	https://creativecommons.org/licenses/by/4.0/	PROPN
fnp-5842	394	21	)	)	PUNCT
fnp-5842	394	22	,	,	PUNCT
fnp-5842	394	23	which	which	PRON
fnp-5842	394	24	permits	permit	VERB
fnp-5842	394	25	unrestricted	unrestricted	ADJ
fnp-5842	394	26	use	use	NOUN
fnp-5842	394	27	,	,	PUNCT
fnp-5842	394	28	distribution	distribution	NOUN
fnp-5842	394	29	,	,	PUNCT
fnp-5842	394	30	and	and	CCONJ
fnp-5842	394	31	reproduction	reproduction	NOUN
fnp-5842	394	32	in	in	ADP
fnp-5842	394	33	any	any	DET
fnp-5842	394	34	medium	medium	NOUN
fnp-5842	394	35	,	,	PUNCT
fnp-5842	394	36	provided	provide	VERB
fnp-5842	394	37	the	the	DET
fnp-5842	394	38	original	original	ADJ
fnp-5842	394	39	author	author	NOUN
fnp-5842	394	40	and	and	CCONJ
fnp-5842	394	41	source	source	NOUN
fnp-5842	394	42	are	be	AUX
fnp-5842	394	43	credited	credit	VERB
fnp-5842	394	44	,	,	PUNCT
fnp-5842	394	45	a	a	DET
fnp-5842	394	46	link	link	NOUN
fnp-5842	394	47	to	to	ADP
fnp-5842	394	48	the	the	DET
fnp-5842	394	49	creative	creative	ADJ
fnp-5842	394	50	commons	common	NOUN
fnp-5842	394	51	license	license	NOUN
fnp-5842	394	52	is	be	AUX
fnp-5842	394	53	provided	provide	VERB
fnp-5842	394	54	,	,	PUNCT
fnp-5842	394	55	and	and	CCONJ
fnp-5842	394	56	any	any	DET
fnp-5842	394	57	changes	change	NOUN
fnp-5842	394	58	are	be	AUX
fnp-5842	394	59	indicated	indicate	VERB
fnp-5842	394	60	.	.	PUNCT
fnp-5842	395	1	the	the	DET
fnp-5842	395	2	creative	creative	ADJ
fnp-5842	395	3	commons	common	NOUN
fnp-5842	395	4	public	public	ADJ
fnp-5842	395	5	domain	domain	NOUN
fnp-5842	395	6	dedication	dedication	NOUN
fnp-5842	395	7	waiver	waiver	NOUN
fnp-5842	395	8	(	(	PUNCT
fnp-5842	395	9	https://creativecommons.org/publicdomain/zero/1.0/	https://creativecommons.org/publicdomain/zero/1.0/	PROPN
fnp-5842	395	10	)	)	PUNCT
fnp-5842	395	11	applies	apply	VERB
fnp-5842	395	12	to	to	ADP
fnp-5842	395	13	the	the	DET
fnp-5842	395	14	data	datum	NOUN
fnp-5842	395	15	made	make	VERB
fnp-5842	395	16	available	available	ADJ
fnp-5842	395	17	in	in	ADP
fnp-5842	395	18	this	this	DET
fnp-5842	395	19	article	article	NOUN
fnp-5842	395	20	,	,	PUNCT
fnp-5842	395	21	unless	unless	SCONJ
fnp-5842	395	22	otherwise	otherwise	ADV
fnp-5842	395	23	stated	state	VERB
fnp-5842	395	24	.	.	PUNCT